ID annotation.Assigned_by annotation.DB annotation.DB:Reference annotation.DB_Object_ID annotation.DB_Object_Name annotation.DB_Object_Type annotation.Date annotation.Evidence annotation.GO BIOLOGICAL_PROCESS annotation.GO CELLULAR_COMPONENT annotation.GO MOLECULAR_FUNCTION annotation.Qualifier annotation.Taxon annotation.With (or) From A1BG UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005576=PMID:3458201} P04217 Alpha-1B-glycoprotein protein 20070222 {GO:0008150=ND, GO:0003674=ND, GO:0005576=IDA} biological_process extracellular region molecular_function Human A1CF HPA UniProtKB {GO:0006397=GO_REF:0000037, GO:0030895=PMID:10781591, GO:0005515=PMID:12896982, GO:0003725=PMID:11871661, GO:0010467=Reactome:REACT_71, GO:0003727=PMID:11871661, GO:0016556=Reactome:REACT_1757, GO:0005783=GO_REF:0000039, GO:0003723=PMID:10669759, GO:0016554=Reactome:REACT_167, GO:0050821=PMID:12881431, GO:0003676=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0000166=GO_REF:0000002, GO:0005654=Reactome:REACT_1850} Q9NQ94 APOBEC1 complementation factor protein 20110516 {GO:0006397=IEA, GO:0030895=IDA, GO:0005515=IPI, GO:0003725=IDA, GO:0010467=TAS, GO:0003727=IDA, GO:0016556=TAS, GO:0005783=IEA, GO:0003723=TAS, GO:0016554=TAS, GO:0050821=IDA, GO:0003676=IEA, GO:0005737=IDA, GO:0000166=IEA, GO:0005654=TAS} cytidine to uridine editing, gene expression, mRNA modification, mRNA processing, protein stabilization apolipoprotein B mRNA editing enzyme complex, cytoplasm, endoplasmic reticulum, nucleoplasm RNA binding, double-stranded RNA binding, nucleic acid binding, nucleotide binding, protein binding, single-stranded RNA binding Human A2M Reactome UniProtKB {GO:0005515=PMID:14687906, GO:0051056=Reactome:REACT_11051, GO:0001869=PMID:12538697, GO:0004866=GO_REF:0000002, GO:0043120=PMID:9714181, GO:0007264=Reactome:REACT_11044, GO:0004867=PMID:12538697, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_21351, GO:0019959=PMID:10880251, GO:0005615=GO_REF:0000002, GO:0005829=Reactome:REACT_9982, GO:0048863=GO_REF:0000019, GO:0019966=PMID:9714181, GO:0019838=PMID:9398211, GO:0007596=Reactome:REACT_2051, GO:0007597=Reactome:REACT_326, GO:0002576=Reactome:REACT_318, GO:0031093=Reactome:REACT_21351, GO:0019899=PMID:11435418} P01023 Alpha-2-macroglobulin protein 20130301 {GO:0005515=IPI, GO:0051056=TAS, GO:0001869=IDA, GO:0004866=IEA, GO:0043120=IDA, GO:0007264=TAS, GO:0004867=IDA, GO:0030168=TAS, GO:0005576=TAS, GO:0019959=IPI, GO:0005615=IEA, GO:0005829=TAS, GO:0048863=IEA, GO:0019966=IDA, GO:0019838=IDA, GO:0007596=TAS, GO:0007597=TAS, GO:0002576=TAS, GO:0031093=TAS, GO:0019899=IPI} blood coagulation, blood coagulation, intrinsic pathway, negative regulation of complement activation, lectin pathway, platelet activation, platelet degranulation, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction, stem cell differentiation cytosol, extracellular region, extracellular space, platelet alpha granule lumen endopeptidase inhibitor activity, enzyme binding, growth factor binding, interleukin-1 binding, interleukin-8 binding, protein binding, serine-type endopeptidase inhibitor activity, tumor necrosis factor binding Human A4GALT MGI UniProtKB {GO:0007009=PMID:10747952, GO:0030173=PMID:10748143, GO:0050512=GO_REF:0000003, GO:0016020=PMID:10748143, GO:0005795=GO_REF:0000002, GO:0006688=PMID:10748143, GO:0006486=GO_REF:0000041, GO:0008378=PMID:10748143} Q9NPC4 Lactosylceramide 4-alpha-galactosyltransferase protein 20120514 {GO:0007009=IDA, GO:0030173=NAS, GO:0050512=IEA, GO:0016020=IDA, GO:0005795=IEA, GO:0006688=NAS, GO:0006486=IEA, GO:0008378=IDA} glycosphingolipid biosynthetic process, plasma membrane organization, protein glycosylation Golgi stack, integral to Golgi membrane, membrane galactosyltransferase activity, lactosylceramide 4-alpha-galactosyltransferase activity Human AAAS HPA UniProtKB {GO:0022415=Reactome:REACT_6361, GO:0005813=GO_REF:0000052, GO:0031965=GO_REF:0000052, GO:0005975=Reactome:REACT_474, GO:0019221=Reactome:REACT_25229, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0005635=Reactome:REACT_115827, GO:0055085=Reactome:REACT_19118, GO:0010827=Reactome:REACT_6804, GO:0008645=Reactome:REACT_9441, GO:0006913=PMID:12730363, GO:0009566=GO_REF:0000019, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0015758=Reactome:REACT_212, GO:0005643=PMID:12730363, GO:0016032=Reactome:REACT_6256, GO:0007612=GO_REF:0000019, GO:0046822=PMID:12730363} Q9NRG9 Aladin protein 20110516 {GO:0022415=TAS, GO:0005813=IDA, GO:0031965=IDA, GO:0005975=TAS, GO:0019221=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0005635=TAS, GO:0055085=TAS, GO:0010827=TAS, GO:0008645=TAS, GO:0006913=IDA, GO:0009566=IEA, GO:0003674=ND, GO:0005737=IDA, GO:0015758=TAS, GO:0005643=IDA, GO:0016032=TAS, GO:0007612=IEA, GO:0046822=NAS} carbohydrate metabolic process, cytokine-mediated signaling pathway, fertilization, glucose transport, hexose transport, learning, nucleocytoplasmic transport, regulation of glucose transport, regulation of nucleocytoplasmic transport, small molecule metabolic process, transmembrane transport, viral reproduction, viral reproductive process centrosome, cytoplasm, nuclear envelope, nuclear membrane, nuclear pore, nucleolus, nucleus molecular_function Human AACS UniProtKB UniProtKB {GO:0007584=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0034201=GO_REF:0000019, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0014074=GO_REF:0000019, GO:0047760=GO_REF:0000019, GO:0005829=GO_REF:0000039, GO:0001889=GO_REF:0000019, GO:0071397=GO_REF:0000019, GO:0042594=GO_REF:0000019, GO:0071394=GO_REF:0000019, GO:0050872=GO_REF:0000019, GO:0006631=GO_REF:0000037, GO:0032024=GO_REF:0000019, GO:0071333=GO_REF:0000019, GO:0060612=GO_REF:0000019, GO:0030729=GO_REF:0000003} Q86V21 Acetoacetyl-CoA synthetase protein 20130413 {GO:0007584=IEA, GO:0042493=IEA, GO:0045471=IEA, GO:0034201=IEA, GO:0003824=IEA, GO:0005524=IEA, GO:0014074=IEA, GO:0047760=IEA, GO:0005829=IEA, GO:0001889=IEA, GO:0071397=IEA, GO:0042594=IEA, GO:0071394=IEA, GO:0050872=IEA, GO:0006631=IEA, GO:0032024=IEA, GO:0071333=IEA, GO:0060612=IEA, GO:0030729=IEA} adipose tissue development, cellular response to cholesterol, cellular response to glucose stimulus, cellular response to testosterone stimulus, fatty acid metabolic process, liver development, positive regulation of insulin secretion, response to drug, response to ethanol, response to nutrient, response to oleic acid, response to purine-containing compound, response to starvation, white fat cell differentiation cytosol ATP binding, acetoacetate-CoA ligase activity, butyrate-CoA ligase activity, catalytic activity Human UniProtKB-SubCell:SL-0091 AADAC PINC UniProtKB {GO:0004091=GO_REF:0000002, GO:0004806=GO_REF:0000024, GO:0016787=GO_REF:0000002, GO:0005789=PMID:19339378, GO:0019213=PMID:9665742, GO:0010898=GO_REF:0000024, GO:0017171=PMID:17936933, GO:0050253=GO_REF:0000003, GO:0016021=GO_REF:0000037, GO:0003824=PMID:8063807, GO:0016298=PMID:11481320} P22760 Arylacetamide deacetylase protein 20030904 {GO:0004091=IEA, GO:0004806=ISS, GO:0016787=IEA, GO:0005789=IDA, GO:0019213=IDA, GO:0010898=ISS, GO:0017171=IDA, GO:0050253=IEA, GO:0016021=IEA, GO:0003824=TAS, GO:0016298=TAS} positive regulation of triglyceride catabolic process endoplasmic reticulum membrane, integral to membrane carboxylesterase activity, catalytic activity, deacetylase activity, hydrolase activity, lipase activity, retinyl-palmitate esterase activity, serine hydrolase activity, triglyceride lipase activity Human AADAT Reactome UniProtKB {GO:0006569=Reactome:REACT_916, GO:0070189=PMID:18620547, GO:0009058=GO_REF:0000002, GO:0006536=PMID:18620547, GO:0033512=GO_REF:0000041, GO:0047536=Reactome:REACT_21297, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0042803=PMID:18620547, GO:0005739=GO_REF:0000019, GO:0034641=Reactome:REACT_13, GO:0019441=GO_REF:0000019, GO:0005759=Reactome:REACT_25131, GO:0030170=GO_REF:0000019, GO:0006103=PMID:18620547, GO:0016212=Reactome:REACT_25131, GO:0006554=Reactome:REACT_1298} Q8N5Z0 Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial protein 20100701 {GO:0006569=TAS, GO:0070189=IDA, GO:0009058=IEA, GO:0006536=IDA, GO:0033512=IEA, GO:0047536=EXP, GO:0044281=TAS, GO:0003824=IEA, GO:0042803=IPI, GO:0005739=IEA, GO:0034641=TAS, GO:0019441=IEA, GO:0005759=TAS, GO:0030170=IEA, GO:0006103=IDA, GO:0016212=TAS, GO:0006554=TAS} 2-oxoglutarate metabolic process, L-lysine catabolic process to acetyl-CoA via saccharopine, biosynthetic process, cellular nitrogen compound metabolic process, glutamate metabolic process, kynurenine metabolic process, lysine catabolic process, small molecule metabolic process, tryptophan catabolic process, tryptophan catabolic process to kynurenine mitochondrial matrix, mitochondrion 2-aminoadipate transaminase activity, catalytic activity, kynurenine-oxoglutarate transaminase activity, protein homodimerization activity, pyridoxal phosphate binding Human AAGAB LIFEdb UniProtKB {GO:0005737=GO_REF:0000054, GO:0015031=GO_REF:0000037, GO:0005829=GO_REF:0000039} Q6PD74 Alpha- and gamma-adaptin-binding protein p34 protein 20100607 {GO:0005737=IDA, GO:0015031=IEA, GO:0005829=IEA} protein transport cytoplasm, cytosol Human AAK1 IntAct UniProtKB {GO:0005515=PMID:22645275, GO:0045747=PMID:21464124, GO:0035612=PMID:17494869, GO:0030136=GO_REF:0000024, GO:0050821=PMID:21464124, GO:0005112=PMID:21464124, GO:0005524=GO_REF:0000037, GO:0006897=GO_REF:0000037, GO:0032880=PMID:18657069, GO:0005905=GO_REF:0000039, GO:0046777=GO_REF:0000024, GO:0004674=GO_REF:0000024, GO:0043195=GO_REF:0000024, GO:2000369=PMID:17494869, GO:0006468=PMID:17494869, GO:0031252=GO_REF:0000024, GO:0019897=GO_REF:0000024} Q2M2I8 AP2-associated protein kinase 1 protein 20130415 {GO:0005515=IPI, GO:0045747=IDA, GO:0035612=IDA, GO:0030136=ISS, GO:0050821=IDA, GO:0005112=IDA, GO:0005524=IEA, GO:0006897=IEA, GO:0032880=IDA, GO:0005905=IEA, GO:0046777=ISS, GO:0004674=ISS, GO:0043195=ISS, GO:2000369=IMP, GO:0006468=IDA, GO:0031252=ISS, GO:0019897=ISS} endocytosis, positive regulation of Notch signaling pathway, protein autophosphorylation, protein phosphorylation, protein stabilization, regulation of clathrin-mediated endocytosis, regulation of protein localization cell leading edge, clathrin-coated vesicle, coated pit, extrinsic to plasma membrane, terminal bouton AP-2 adaptor complex binding, ATP binding, Notch binding, protein binding, protein serine/threonine kinase activity Human UniProtKB:Q9NQ11 AAMP PINC UniProtKB {GO:0010595=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0009986=PMID:10329261, GO:0005886=GO_REF:0000039, GO:0014909=PMID:18634987, GO:0001525=PMID:10329261, GO:0008201=PMID:7743515, GO:0030154=GO_REF:0000037} Q13685 Angio-associated migratory cell protein protein 20030904 {GO:0010595=ISS, GO:0005737=IEA, GO:0009986=IDA, GO:0005886=IEA, GO:0014909=IEP, GO:0001525=NAS, GO:0008201=TAS, GO:0030154=IEA} angiogenesis, cell differentiation, positive regulation of endothelial cell migration, smooth muscle cell migration cell surface, cytoplasm, plasma membrane heparin binding Human AANAT Reactome UniProtKB {GO:0032868=GO_REF:0000019, GO:0051412=GO_REF:0000019, GO:0048471=PMID:11313340, GO:0030187=PMID:11313340, GO:0044281=Reactome:REACT_111217, GO:0010043=GO_REF:0000019, GO:0051591=GO_REF:0000019, GO:0005829=Reactome:REACT_15290, GO:0034641=Reactome:REACT_13, GO:0071889=GO_REF:0000019, GO:0051592=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0046219=Reactome:REACT_15439, GO:0034695=GO_REF:0000019, GO:0004060=GO_REF:0000019, GO:0007623=PMID:12736803, GO:0009416=GO_REF:0000019, GO:0004059=PMID:8661026, GO:0071320=PMID:11313340, GO:0034097=GO_REF:0000019, GO:0046688=GO_REF:0000019, GO:0006474=PMID:11313340} Q16613 Serotonin N-acetyltransferase protein 20130301 {GO:0032868=IEA, GO:0051412=IEA, GO:0048471=IDA, GO:0030187=IDA, GO:0044281=TAS, GO:0010043=IEA, GO:0051591=IEA, GO:0005829=TAS, GO:0034641=TAS, GO:0071889=IEA, GO:0051592=IEA, GO:0005737=IEA, GO:0046219=TAS, GO:0034695=IEA, GO:0004060=IEA, GO:0007623=IMP, GO:0009416=IEA, GO:0004059=NAS, GO:0071320=IDA, GO:0034097=IEA, GO:0046688=IEA, GO:0006474=IDA} N-terminal protein amino acid acetylation, cellular nitrogen compound metabolic process, cellular response to cAMP, circadian rhythm, indolalkylamine biosynthetic process, melatonin biosynthetic process, response to cAMP, response to calcium ion, response to copper ion, response to corticosterone stimulus, response to cytokine stimulus, response to insulin stimulus, response to light stimulus, response to prostaglandin E stimulus, response to zinc ion, small molecule metabolic process cytoplasm, cytosol, perinuclear region of cytoplasm 14-3-3 protein binding, aralkylamine N-acetyltransferase activity, arylamine N-acetyltransferase activity Human AARS Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0002161=GO_REF:0000019, GO:0000049=GO_REF:0000019, GO:0006419=GO_REF:0000019, GO:0004813=GO_REF:0000003, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000019, GO:0008033=PMID:7654687, GO:0046872=GO_REF:0000037, GO:0006400=GO_REF:0000019, GO:0006418=Reactome:REACT_15482, GO:0005829=Reactome:REACT_15409, GO:0030968=GO_REF:0000019, GO:0043524=GO_REF:0000019, GO:0005737=PMID:7654687, GO:0006457=GO_REF:0000019, GO:0021680=GO_REF:0000019, GO:0050885=GO_REF:0000019, GO:0043588=GO_REF:0000019, GO:0043200=GO_REF:0000019, GO:0001942=GO_REF:0000019, GO:0016597=GO_REF:0000019} P49588 Alanine--tRNA ligase, cytoplasmic protein 20130301 {GO:0010467=TAS, GO:0002161=IEA, GO:0000049=IEA, GO:0006419=IEA, GO:0004813=IEA, GO:0003676=IEA, GO:0005524=IEA, GO:0008033=TAS, GO:0046872=IEA, GO:0006400=IEA, GO:0006418=TAS, GO:0005829=TAS, GO:0030968=IEA, GO:0043524=IEA, GO:0005737=TAS, GO:0006457=IEA, GO:0021680=IEA, GO:0050885=IEA, GO:0043588=IEA, GO:0043200=IEA, GO:0001942=IEA, GO:0016597=IEA} alanyl-tRNA aminoacylation, cerebellar Purkinje cell layer development, endoplasmic reticulum unfolded protein response, gene expression, hair follicle development, negative regulation of neuron apoptotic process, neuromuscular process controlling balance, protein folding, response to amino acid stimulus, skin development, tRNA aminoacylation for protein translation, tRNA modification, tRNA processing cytoplasm, cytosol ATP binding, alanine-tRNA ligase activity, amino acid binding, aminoacyl-tRNA editing activity, metal ion binding, nucleic acid binding, tRNA binding Human AARS2 BHF-UCL UniProtKB {GO:0005739=GO_REF:0000052, GO:0010467=Reactome:REACT_71, GO:0000049=GO_REF:0000037, GO:0033108=PMID:21549344, GO:0070143=PMID:21549344, GO:0004813=PMID:21549344, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0006418=Reactome:REACT_15482} Q5JTZ9 Alanine--tRNA ligase, mitochondrial protein 20120510 {GO:0005739=IDA, GO:0010467=TAS, GO:0000049=IEA, GO:0033108=IMP, GO:0070143=IMP, GO:0004813=IMP, GO:0005524=IEA, GO:0046872=IEA, GO:0006418=TAS} gene expression, mitochondrial alanyl-tRNA aminoacylation, mitochondrial respiratory chain complex assembly, tRNA aminoacylation for protein translation mitochondrion ATP binding, alanine-tRNA ligase activity, metal ion binding, tRNA binding Human AARSD1 BHF-UCL UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0006419=GO_REF:0000002, GO:0004813=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0003676=GO_REF:0000002, GO:0043039=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0016876=GO_REF:0000002} Q9BTE6 Alanyl-tRNA editing protein Aarsd1 protein 20120510 {GO:0003674=ND, GO:0008150=ND, GO:0005737=IEA, GO:0000166=IEA, GO:0006419=IEA, GO:0004813=IEA, GO:0005575=ND, GO:0003676=IEA, GO:0043039=IEA, GO:0005524=IEA, GO:0046872=IEA, GO:0016876=IEA} alanyl-tRNA aminoacylation, biological_process, tRNA aminoacylation cellular_component, cytoplasm ATP binding, alanine-tRNA ligase activity, ligase activity, forming aminoacyl-tRNA and related compounds, metal ion binding, molecular_function, nucleic acid binding, nucleotide binding Human AASDHPPT Reactome UniProtKB {GO:0005515=PMID:18022563, GO:0000287=PMID:18022563, GO:0015939=Reactome:REACT_11172, GO:0006766=Reactome:REACT_11193, GO:0009059=GO_REF:0000002, GO:0006767=Reactome:REACT_11238, GO:0006633=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0008897=PMID:18022563, GO:0005829=Reactome:REACT_11175} Q9NRN7 L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase protein 20130301 {GO:0005515=IPI, GO:0000287=IDA, GO:0015939=TAS, GO:0006766=TAS, GO:0009059=IEA, GO:0006767=TAS, GO:0006633=IEA, GO:0044281=TAS, GO:0008897=IDA, GO:0005829=TAS} fatty acid biosynthetic process, macromolecule biosynthetic process, pantothenate metabolic process, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cytosol "holo-acyl-carrier-protein"" synthase activity, magnesium ion binding, protein binding""" Human AASS HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000052, GO:0051262=PMID:10567240, GO:0033512=GO_REF:0000041, GO:0005759=Reactome:REACT_2132, GO:0016491=GO_REF:0000002, GO:0047130=Reactome:REACT_75, GO:0047131=Reactome:REACT_2132, GO:0044281=Reactome:REACT_111217, GO:0006554=Reactome:REACT_1298, GO:0043231=GO_REF:0000052} Q9UDR5 Alpha-aminoadipic semialdehyde synthase, mitochondrial protein 20101115 {GO:0005739=IDA, GO:0034641=TAS, GO:0005737=IDA, GO:0051262=TAS, GO:0033512=IEA, GO:0005759=TAS, GO:0016491=IEA, GO:0047130=EXP, GO:0047131=EXP, GO:0044281=TAS, GO:0006554=TAS, GO:0043231=IDA} L-lysine catabolic process to acetyl-CoA via saccharopine, cellular nitrogen compound metabolic process, lysine catabolic process, protein tetramerization, small molecule metabolic process cytoplasm, intracellular membrane-bounded organelle, mitochondrial matrix, mitochondrion oxidoreductase activity, saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity, saccharopine dehydrogenase (NADP+, L-lysine-forming) activity Human AATF HPA UniProtKB {GO:0005515=PMID:17157788, GO:0005813=GO_REF:0000052, GO:0048011=Reactome:REACT_13776, GO:0043066=PMID:15207272, GO:0005794=GO_REF:0000019, GO:0003700=PMID:10580117, GO:0042254=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0048156=GO_REF:0000019, GO:0006915=Reactome:REACT_13638, GO:0032929=PMID:15207272, GO:0005634=GO_REF:0000052, GO:0097190=Reactome:REACT_13720, GO:0042985=GO_REF:0000019, GO:0006974=PMID:18049476, GO:0043522=PMID:14627703, GO:0007346=GO_REF:0000019, GO:0005737=PMID:15207272, GO:0040016=GO_REF:0000019, GO:0045944=PMID:18049476, GO:2000378=PMID:15207272, GO:0007155=GO_REF:0000019, GO:0005925=GO_REF:0000052} Q9NY61 Protein AATF protein 20101115 {GO:0005515=IPI, GO:0005813=IDA, GO:0048011=TAS, GO:0043066=IMP, GO:0005794=IEA, GO:0003700=IDA, GO:0042254=IEA, GO:0005730=IDA, GO:0048156=IEA, GO:0006915=TAS, GO:0032929=IDA, GO:0005634=IDA, GO:0097190=TAS, GO:0042985=IEA, GO:0006974=IEP, GO:0043522=IPI, GO:0007346=IEA, GO:0005737=IDA, GO:0040016=IEA, GO:0045944=IDA, GO:2000378=IDA, GO:0007155=IEA, GO:0005925=IDA} apoptotic process, apoptotic signaling pathway, cell adhesion, embryonic cleavage, negative regulation of amyloid precursor protein biosynthetic process, negative regulation of apoptotic process, negative regulation of reactive oxygen species metabolic process, negative regulation of superoxide anion generation, neurotrophin TRK receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, regulation of mitotic cell cycle, response to DNA damage stimulus, ribosome biogenesis Golgi apparatus, centrosome, cytoplasm, focal adhesion, nucleolus, nucleus leucine zipper domain binding, protein binding, sequence-specific DNA binding transcription factor activity, tau protein binding Human AATK HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0048471=GO_REF:0000039, GO:0046777=GO_REF:0000019, GO:0004674=GO_REF:0000037, GO:0006915=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0004713=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q6ZMQ8 Serine/threonine-protein kinase LMTK1 protein 20080205 {GO:0005739=IDA, GO:0048471=IEA, GO:0046777=IEA, GO:0004674=IEA, GO:0006915=IEA, GO:0016021=IEA, GO:0004713=IEA, GO:0005524=IEA} apoptotic process, protein autophosphorylation integral to membrane, mitochondrion, perinuclear region of cytoplasm ATP binding, protein serine/threonine kinase activity, protein tyrosine kinase activity Human ABAT LIFEdb UniProtKB {GO:0001666=GO_REF:0000019, GO:0043005=GO_REF:0000019, GO:0003867=Reactome:REACT_23980, GO:0042493=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0048148=GO_REF:0000024, GO:0045776=GO_REF:0000019, GO:0047298=GO_REF:0000003, GO:0007269=Reactome:REACT_13723, GO:0042803=PMID:15528998, GO:0005739=GO_REF:0000054, GO:0032145=GO_REF:0000024, GO:0032144=PMID:15528998, GO:0005759=Reactome:REACT_23980, GO:0030170=PMID:15650327, GO:0010039=GO_REF:0000019, GO:0007610=PMID:11918424, GO:0009450=PMID:15528998, GO:0007626=GO_REF:0000019, GO:0042135=PMID:15528998, GO:0007620=GO_REF:0000019, GO:0009448=GO_REF:0000002, GO:0035094=GO_REF:0000019} P80404 4-aminobutyrate aminotransferase, mitochondrial protein 20100607 {GO:0001666=IEA, GO:0043005=IEA, GO:0003867=TAS, GO:0042493=IEA, GO:0045471=IEA, GO:0007268=TAS, GO:0048148=ISS, GO:0045776=IEA, GO:0047298=IEA, GO:0007269=TAS, GO:0042803=IPI, GO:0005739=IDA, GO:0032145=ISS, GO:0032144=IDA, GO:0005759=TAS, GO:0030170=IDA, GO:0010039=IEA, GO:0007610=NAS, GO:0009450=NAS, GO:0007626=IEA, GO:0042135=NAS, GO:0007620=IEA, GO:0009448=IEA, GO:0035094=IEA} behavior, behavioral response to cocaine, copulation, gamma-aminobutyric acid catabolic process, gamma-aminobutyric acid metabolic process, locomotory behavior, negative regulation of blood pressure, neurotransmitter catabolic process, neurotransmitter secretion, response to drug, response to ethanol, response to hypoxia, response to iron ion, response to nicotine, synaptic transmission 4-aminobutyrate transaminase complex, mitochondrial matrix, mitochondrion, neuron projection (S)-3-amino-2-methylpropionate transaminase activity, 4-aminobutyrate transaminase activity, protein homodimerization activity, pyridoxal phosphate binding, succinate-semialdehyde dehydrogenase binding Human ABCA1 GOC UniProtKB {GO:0005515=PMID:12084722, GO:0008509=GO_REF:0000024, GO:0031267=PMID:16443932, GO:0071300=GO_REF:0000019, GO:0006497=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0042632=PMID:10431236, GO:0019905=PMID:15469992, GO:0033344=PMID:11162594, GO:0005794=GO_REF:0000019, GO:0010745=PMID:18490524, GO:0050702=PMID:11855831, GO:0043691=PMID:10431236, GO:0005548=PMID:16702602, GO:0038027=PMID:16443932, GO:0055098=PMID:15358760, GO:0007186=PMID:16443932, GO:0005887=PMID:10525055, GO:0042157=Reactome:REACT_13621, GO:0055091=PMID:16702602, GO:0045121=PMID:15469992, GO:0007040=PMID:15163665, GO:0032367=PMID:10431236, GO:0006629=Reactome:REACT_602, GO:0005886=Reactome:REACT_115994, GO:0030819=PMID:14701824, GO:0017127=PMID:12084722, GO:0030139=PMID:14747463, GO:0044281=Reactome:REACT_111217, GO:0010875=GO_REF:0000019, GO:0045332=GO_REF:0000019, GO:0005543=PMID:16702602, GO:0015485=PMID:12084722, GO:0016197=PMID:14747463, GO:0034380=PMID:17305370, GO:0016887=GO_REF:0000002, GO:0008203=PMID:14747463, GO:0002790=GO_REF:0000019, GO:0032489=PMID:16443932, GO:0005524=PMID:11700048, GO:0006911=GO_REF:0000019, GO:0010887=PMID:18490524, GO:0045335=PMID:15469992, GO:0033700=PMID:11162594, GO:0071222=GO_REF:0000019, GO:0034616=PMID:15358760, GO:0060155=PMID:15163665, GO:0034185=PMID:11162594, GO:0034186=PMID:11162594, GO:0034188=PMID:16443932} O95477 ATP-binding cassette sub-family A member 1 protein 20130413 {GO:0005515=IPI, GO:0008509=ISS, GO:0031267=IPI, GO:0071300=IEA, GO:0006497=IEA, GO:0044255=TAS, GO:0042632=IDA, GO:0019905=IPI, GO:0033344=IDA, GO:0005794=IEA, GO:0010745=TAS, GO:0050702=IMP, GO:0043691=IMP, GO:0005548=IDA, GO:0038027=IDA, GO:0055098=IEP, GO:0007186=IMP, GO:0005887=IDA, GO:0042157=TAS, GO:0055091=IMP, GO:0045121=IDA, GO:0007040=IDA, GO:0032367=IMP, GO:0006629=TAS, GO:0005886=TAS, GO:0030819=IMP, GO:0017127=IDA, GO:0030139=IDA, GO:0044281=TAS, GO:0010875=IEA, GO:0045332=IEA, GO:0005543=IC, GO:0015485=IC, GO:0016197=IDA, GO:0034380=IMP, GO:0016887=IEA, GO:0008203=IDA, GO:0002790=IEA, GO:0032489=IMP, GO:0005524=IDA, GO:0006911=IEA, GO:0010887=TAS, GO:0045335=IDA, GO:0033700=IDA, GO:0071222=IEA, GO:0034616=IEP, GO:0060155=IMP, GO:0034185=IPI, GO:0034186=IPI, GO:0034188=IDA} G-protein coupled receptor signaling pathway, apolipoprotein A-I-mediated signaling pathway, cellular lipid metabolic process, cellular response to lipopolysaccharide, cellular response to retinoic acid, cholesterol efflux, cholesterol homeostasis, cholesterol metabolic process, endosomal transport, high-density lipoprotein particle assembly, interleukin-1 beta secretion, intracellular cholesterol transport, lipid metabolic process, lipoprotein metabolic process, lysosome organization, negative regulation of cholesterol storage, negative regulation of macrophage derived foam cell differentiation, peptide secretion, phagocytosis, engulfment, phospholipid efflux, phospholipid homeostasis, phospholipid translocation, platelet dense granule organization, positive regulation of cAMP biosynthetic process, positive regulation of cholesterol efflux, protein lipidation, regulation of Cdc42 protein signal transduction, response to laminar fluid shear stress, response to low-density lipoprotein particle stimulus, reverse cholesterol transport, small molecule metabolic process Golgi apparatus, endocytic vesicle, integral to plasma membrane, membrane raft, phagocytic vesicle, plasma membrane ATP binding, ATPase activity, anion transmembrane transporter activity, apolipoprotein A-I binding, apolipoprotein A-I receptor activity, apolipoprotein binding, cholesterol binding, cholesterol transporter activity, phospholipid binding, phospholipid transporter activity, protein binding, small GTPase binding, syntaxin binding Human ABCA10 UniProtKB UniProtKB {GO:0006810=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002} Q8WWZ4 ATP-binding cassette sub-family A member 10 protein 20130413 {GO:0006810=IEA, GO:0016021=IEA, GO:0005524=IEA, GO:0016887=IEA} transport integral to membrane ATP binding, ATPase activity Human UniProtKB-KW:KW-0812 ABCA12 UniProtKB UniProtKB {GO:0019725=PMID:12697999, GO:0035627=GO_REF:0000019, GO:0048286=GO_REF:0000019, GO:0005743=GO_REF:0000019, GO:0031424=GO_REF:0000019, GO:0055088=GO_REF:0000019, GO:0061436=GO_REF:0000019, GO:0005524=PMID:12697999, GO:0005829=GO_REF:0000019, GO:0006869=PMID:12915478, GO:0043129=GO_REF:0000019, GO:0016021=PMID:12697999, GO:0016887=GO_REF:0000002} Q86UK0 ATP-binding cassette sub-family A member 12 protein 20050704 {GO:0019725=NAS, GO:0035627=IEA, GO:0048286=IEA, GO:0005743=IEA, GO:0031424=IEA, GO:0055088=IEA, GO:0061436=IEA, GO:0005524=NAS, GO:0005829=IEA, GO:0006869=NAS, GO:0043129=IEA, GO:0016021=NAS, GO:0016887=IEA} cellular homeostasis, ceramide transport, establishment of skin barrier, keratinization, lipid homeostasis, lipid transport, lung alveolus development, surfactant homeostasis cytosol, integral to membrane, mitochondrial inner membrane ATP binding, ATPase activity Human ABCA13 UniProtKB UniProtKB {GO:0006810=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002} Q86UQ4 ATP-binding cassette sub-family A member 13 protein 20130413 {GO:0006810=IEA, GO:0016021=IEA, GO:0005524=IEA, GO:0016887=IEA} transport integral to membrane ATP binding, ATPase activity Human UniProtKB-KW:KW-0812 ABCA2 GOC UniProtKB {GO:0042632=PMID:15238223, GO:0006629=PMID:11178988, GO:0006200=PMID:15999530, GO:0005815=GO_REF:0000024, GO:0006357=PMID:15238223, GO:0042493=PMID:12363033, GO:0042626=PMID:7766993, GO:0048545=PMID:15238223, GO:0005765=PMID:11309290, GO:0005764=PMID:11309290, GO:0005524=GO_REF:0000024, GO:0000166=PMID:12363033, GO:0006810=PMID:7766993, GO:0016023=GO_REF:0000024, GO:0016021=PMID:12363033, GO:0032383=PMID:15238223, GO:0016887=PMID:15999530, GO:0043190=PMID:11178988, GO:0010008=GO_REF:0000039, GO:0005768=PMID:11309290} Q9BZC7 ATP-binding cassette sub-family A member 2 protein 20130413 {GO:0042632=IEP, GO:0006629=NAS, GO:0006200=IDA, GO:0005815=ISS, GO:0006357=IDA, GO:0042493=TAS, GO:0042626=NAS, GO:0048545=IEP, GO:0005765=RCA, GO:0005764=IDA, GO:0005524=ISS, GO:0000166=RCA, GO:0006810=NAS, GO:0016023=ISS, GO:0016021=RCA, GO:0032383=IMP, GO:0016887=IDA, GO:0043190=NAS, GO:0010008=IEA, GO:0005768=IDA} ATP catabolic process, cholesterol homeostasis, lipid metabolic process, regulation of intracellular cholesterol transport, regulation of transcription from RNA polymerase II promoter, response to drug, response to steroid hormone stimulus, transport ATP-binding cassette (ABC) transporter complex, cytoplasmic membrane-bounded vesicle, endosome, endosome membrane, integral to membrane, lysosomal membrane, lysosome, microtubule organizing center ATP binding, ATPase activity, ATPase activity, coupled to transmembrane movement of substances, nucleotide binding Human ABCA3 Reactome UniProtKB {GO:0005215=PMID:9027511, GO:0097233=GO_REF:0000019, GO:0005886=Reactome:REACT_111169, GO:0016020=PMID:9027511, GO:0097208=PMID:11718719, GO:0042493=PMID:8706931, GO:0006810=PMID:15531465, GO:0042626=PMID:9027511, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002} Q99758 ATP-binding cassette sub-family A member 3 protein 20130301 {GO:0005215=TAS, GO:0097233=IEA, GO:0005886=TAS, GO:0016020=TAS, GO:0097208=IDA, GO:0042493=TAS, GO:0006810=IDA, GO:0042626=TAS, GO:0016021=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0016887=IEA} response to drug, transmembrane transport, transport alveolar lamellar body, alveolar lamellar body membrane, integral to membrane, membrane, plasma membrane ATP binding, ATPase activity, ATPase activity, coupled to transmembrane movement of substances, transporter activity Human ABCA4 Reactome UniProtKB {GO:0005215=PMID:9054934, GO:0006649=GO_REF:0000019, GO:0007603=Reactome:REACT_160125, GO:0042626=GO_REF:0000002, GO:0045494=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0001523=Reactome:REACT_160156, GO:0097381=Reactome:REACT_111189, GO:0016020=PMID:9054934, GO:0005887=GO_REF:0000002, GO:0004012=GO_REF:0000019, GO:0006810=PMID:9054934, GO:0016887=GO_REF:0000002, GO:0007601=PMID:9425888} P78363 Retinal-specific ATP-binding cassette transporter protein 20121026 {GO:0005215=TAS, GO:0006649=IEA, GO:0007603=TAS, GO:0042626=IEA, GO:0045494=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0001523=TAS, GO:0097381=TAS, GO:0016020=TAS, GO:0005887=IEA, GO:0004012=IEA, GO:0006810=TAS, GO:0016887=IEA, GO:0007601=TAS} phospholipid transfer to membrane, photoreceptor cell maintenance, phototransduction, visible light, retinoid metabolic process, transmembrane transport, transport, visual perception integral to plasma membrane, membrane, photoreceptor disc membrane ATP binding, ATPase activity, ATPase activity, coupled to transmembrane movement of substances, phospholipid-translocating ATPase activity, transporter activity Human ABCA5 BHF-UCL UniProtKB {GO:0033344=PMID:20382126, GO:0010745=PMID:20382126, GO:0000139=GO_REF:0000039, GO:0005770=PMID:15870284, GO:0043691=PMID:20382126, GO:0034375=PMID:20382126, GO:0031902=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0005765=GO_REF:0000039, GO:0005764=PMID:15870284, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002} Q8WWZ7 ATP-binding cassette sub-family A member 5 protein 20100601 {GO:0033344=ISS, GO:0010745=ISS, GO:0000139=IEA, GO:0005770=ISS, GO:0043691=IC, GO:0034375=ISS, GO:0031902=IEA, GO:0016021=IEA, GO:0005765=IEA, GO:0005764=ISS, GO:0005524=IEA, GO:0016887=IEA} cholesterol efflux, high-density lipoprotein particle remodeling, negative regulation of macrophage derived foam cell differentiation, reverse cholesterol transport Golgi membrane, integral to membrane, late endosome, late endosome membrane, lysosomal membrane, lysosome ATP binding, ATPase activity Human GO:0034375 ABCA6 UniProtKB UniProtKB {GO:0006810=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002} Q8N139 ATP-binding cassette sub-family A member 6 protein 20130413 {GO:0006810=IEA, GO:0016021=IEA, GO:0005524=IEA, GO:0016887=IEA} transport integral to membrane ATP binding, ATPase activity Human UniProtKB-KW:KW-0812 ABCA7 HPA UniProtKB {GO:0006909=GO_REF:0000037, GO:0005215=PMID:10873640, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005548=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0005622=GO_REF:0000019, GO:0033700=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0016324=GO_REF:0000019, GO:0000139=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0016887=GO_REF:0000002, GO:0043190=PMID:10873640, GO:0010008=GO_REF:0000039} Q8IZY2 ATP-binding cassette sub-family A member 7 protein 20110516 {GO:0006909=IEA, GO:0005215=TAS, GO:0005794=IDA, GO:0005886=IDA, GO:0005548=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0005622=IEA, GO:0033700=IEA, GO:0005737=IDA, GO:0016324=IEA, GO:0000139=IEA, GO:0016021=IEA, GO:0016887=IEA, GO:0043190=TAS, GO:0010008=IEA} phagocytosis, phospholipid efflux, transmembrane transport ATP-binding cassette (ABC) transporter complex, Golgi apparatus, Golgi membrane, apical plasma membrane, cytoplasm, endosome membrane, integral to membrane, intracellular, plasma membrane ATP binding, ATPase activity, phospholipid transporter activity, transporter activity Human ABCA9 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0006810=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002} Q8IUA7 ATP-binding cassette sub-family A member 9 protein 20130413 {GO:0005739=IEA, GO:0006810=IEA, GO:0016021=IEA, GO:0005524=IEA, GO:0016887=IEA} transport integral to membrane, mitochondrion ATP binding, ATPase activity Human Ensembl:ENSMUSP00000036338 ABCB1 IntAct UniProtKB {GO:0005515=PMID:20711237, GO:0005215=PMID:3022150, GO:0005886=Reactome:REACT_111164, GO:0009986=PMID:12493773, GO:0042493=PMID:3022150, GO:0072089=PMID:19384922, GO:0042626=GO_REF:0000033, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0008559=GO_REF:0000003, GO:0016324=GO_REF:0000033, GO:0046581=GO_REF:0000033, GO:0000139=GO_REF:0000033, GO:0016020=PMID:3022150, GO:0006855=Reactome:REACT_120801, GO:0000086=PMID:19384922, GO:0006810=PMID:3022150, GO:0016021=GO_REF:0000033} P08183 Multidrug resistance protein 1 protein 20130415 {GO:0005515=IPI, GO:0005215=TAS, GO:0005886=TAS, GO:0009986=IDA, GO:0042493=TAS, GO:0072089=IMP, GO:0042626=IBA, GO:0044281=TAS, GO:0005524=IEA, GO:0055085=TAS, GO:0008559=IEA, GO:0016324=IBA, GO:0046581=IBA, GO:0000139=IBA, GO:0016020=TAS, GO:0006855=TAS, GO:0000086=IDA, GO:0006810=TAS, GO:0016021=IBA} G2/M transition of mitotic cell cycle, drug transmembrane transport, response to drug, small molecule metabolic process, stem cell proliferation, transmembrane transport, transport Golgi membrane, apical plasma membrane, cell surface, integral to membrane, intercellular canaliculus, membrane, plasma membrane ATP binding, ATPase activity, coupled to transmembrane movement of substances, protein binding, transporter activity, xenobiotic-transporting ATPase activity Human UniProtKB:Q86VI4 ABCB10 UniProtKB UniProtKB {GO:0005215=PMID:10922475, GO:0005886=GO_REF:0000033, GO:0032592=PMID:10922475, GO:0006810=PMID:10922475, GO:0005743=GO_REF:0000033, GO:0055085=GO_REF:0000033, GO:0005524=GO_REF:0000037, GO:0015421=GO_REF:0000033, GO:0042803=GO_REF:0000019} Q9NRK6 ATP-binding cassette sub-family B member 10, mitochondrial protein 20100208 {GO:0005215=NAS, GO:0005886=IRD, GO:0032592=IDA, GO:0006810=NAS, GO:0005743=IBA, GO:0055085=IBA, GO:0005524=IEA, GO:0015421=IBA, GO:0042803=IEA} transmembrane transport, transport integral to mitochondrial membrane, mitochondrial inner membrane, plasma membrane ATP binding, oligopeptide-transporting ATPase activity, protein homodimerization activity, transporter activity Human ABCB11 Reactome UniProtKB {GO:0005215=PMID:9806540, GO:0005886=Reactome:REACT_10101, GO:0006699=Reactome:REACT_11054, GO:0042626=GO_REF:0000033, GO:0015126=GO_REF:0000033, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0055085=GO_REF:0000033, GO:0016324=GO_REF:0000033, GO:0046581=GO_REF:0000033, GO:0016020=PMID:9806540, GO:0000139=GO_REF:0000033, GO:0005887=PMID:9806540, GO:0015721=Reactome:REACT_11042, GO:0015722=GO_REF:0000033, GO:0008554=PMID:9806540, GO:0015432=PMID:9806540, GO:0006810=PMID:9806540, GO:0008206=Reactome:REACT_11040, GO:0016021=GO_REF:0000033} O95342 Bile salt export pump protein 20130301 {GO:0005215=TAS, GO:0005886=TAS, GO:0006699=TAS, GO:0042626=IBA, GO:0015126=IBA, GO:0044281=TAS, GO:0005524=IEA, GO:0055085=IBA, GO:0016324=IBA, GO:0046581=IBA, GO:0016020=TAS, GO:0000139=IBA, GO:0005887=TAS, GO:0015721=TAS, GO:0015722=IBA, GO:0008554=TAS, GO:0015432=TAS, GO:0006810=TAS, GO:0008206=TAS, GO:0016021=IBA} bile acid and bile salt transport, bile acid biosynthetic process, bile acid metabolic process, canalicular bile acid transport, small molecule metabolic process, transmembrane transport, transport Golgi membrane, apical plasma membrane, integral to membrane, integral to plasma membrane, intercellular canaliculus, membrane, plasma membrane ATP binding, ATPase activity, coupled to transmembrane movement of substances, bile acid-exporting ATPase activity, canalicular bile acid transmembrane transporter activity, sodium-exporting ATPase activity, phosphorylative mechanism, transporter activity Human ABCB4 Reactome UniProtKB {GO:0006629=PMID:7912658, GO:0005886=Reactome:REACT_115807, GO:0042493=PMID:7912658, GO:0042626=GO_REF:0000033, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0055085=GO_REF:0000033, GO:0046581=GO_REF:0000033, GO:0008559=GO_REF:0000003, GO:0016324=GO_REF:0000033, GO:0016020=PMID:7912658, GO:0000139=GO_REF:0000033, GO:0005887=PMID:7912658, GO:0006810=PMID:8106172, GO:0016021=GO_REF:0000033, GO:0044255=Reactome:REACT_22279} P21439 Multidrug resistance protein 3 protein 20130301 {GO:0006629=TAS, GO:0005886=TAS, GO:0042493=TAS, GO:0042626=IBA, GO:0044281=TAS, GO:0005524=IEA, GO:0055085=IBA, GO:0046581=IBA, GO:0008559=IEA, GO:0016324=IBA, GO:0016020=TAS, GO:0000139=IBA, GO:0005887=TAS, GO:0006810=TAS, GO:0016021=IBA, GO:0044255=TAS} cellular lipid metabolic process, lipid metabolic process, response to drug, small molecule metabolic process, transmembrane transport, transport Golgi membrane, apical plasma membrane, integral to membrane, integral to plasma membrane, intercellular canaliculus, membrane, plasma membrane ATP binding, ATPase activity, coupled to transmembrane movement of substances, xenobiotic-transporting ATPase activity Human ABCB5 Reactome UniProtKB {GO:0046581=GO_REF:0000033, GO:0016324=GO_REF:0000033, GO:0005886=Reactome:REACT_111164, GO:0015562=PMID:12960149, GO:0000139=GO_REF:0000033, GO:0005887=PMID:12960149, GO:0042391=PMID:12960149, GO:0042626=GO_REF:0000033, GO:0016021=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037} Q2M3G0 ATP-binding cassette sub-family B member 5 protein 20130301 {GO:0046581=IBA, GO:0016324=IBA, GO:0005886=TAS, GO:0015562=IDA, GO:0000139=IBA, GO:0005887=IDA, GO:0042391=IDA, GO:0042626=IBA, GO:0016021=IEA, GO:0055085=TAS, GO:0005524=IEA} regulation of membrane potential, transmembrane transport Golgi membrane, apical plasma membrane, integral to membrane, integral to plasma membrane, intercellular canaliculus, plasma membrane ATP binding, ATPase activity, coupled to transmembrane movement of substances, efflux transmembrane transporter activity Human ABCB6 Reactome UniProtKB {GO:0015886=PMID:17661442, GO:0015439=PMID:17006453, GO:0005886=PMID:17661442, GO:0015562=PMID:17661442, GO:0015232=Reactome:REACT_111156, GO:0005783=PMID:22226084, GO:0071585=GO_REF:0000033, GO:0042626=GO_REF:0000002, GO:0005741=Reactome:REACT_111156, GO:0005740=PMID:10837493, GO:0006879=PMID:11977179, GO:0005739=PMID:18279659, GO:0070574=GO_REF:0000033, GO:0006810=PMID:10837493, GO:0043190=PMID:11955620, GO:0005774=GO_REF:0000033, GO:0005794=PMID:22226084, GO:0005524=PMID:10837493, GO:0055085=Reactome:REACT_15518, GO:0006779=PMID:17006453, GO:0007420=PMID:22100072, GO:0043588=PMID:22100072, GO:0016021=GO_REF:0000002, GO:0031307=PMID:17661442, GO:0020037=PMID:17006453} Q9NP58 ATP-binding cassette sub-family B member 6, mitochondrial protein 20110704 {GO:0015886=IDA, GO:0015439=IMP, GO:0005886=IDA, GO:0015562=IDA, GO:0015232=TAS, GO:0005783=IDA, GO:0071585=IBA, GO:0042626=IEA, GO:0005741=TAS, GO:0005740=IDA, GO:0006879=NAS, GO:0005739=IDA, GO:0070574=IBA, GO:0006810=IDA, GO:0043190=NAS, GO:0005774=IBA, GO:0005794=IDA, GO:0005524=IDA, GO:0055085=TAS, GO:0006779=IDA, GO:0007420=IMP, GO:0043588=IMP, GO:0016021=IEA, GO:0031307=IDA, GO:0020037=IDA} brain development, cadmium ion transmembrane transport, cellular iron ion homeostasis, detoxification of cadmium ion, heme transport, porphyrin-containing compound biosynthetic process, skin development, transmembrane transport, transport ATP-binding cassette (ABC) transporter complex, Golgi apparatus, endoplasmic reticulum, integral to membrane, integral to mitochondrial outer membrane, mitochondrial envelope, mitochondrial outer membrane, mitochondrion, plasma membrane, vacuolar membrane ATP binding, ATPase activity, coupled to transmembrane movement of substances, efflux transmembrane transporter activity, heme binding, heme transporter activity, heme-transporting ATPase activity Human ABCB7 GOC UniProtKB {GO:0006879=GO_REF:0000033, GO:0005739=GO_REF:0000052, GO:0015886=PMID:9621516, GO:0005737=GO_REF:0000052, GO:0015232=PMID:9621516, GO:0006810=PMID:9621516, GO:0005743=Reactome:REACT_22342, GO:0042626=GO_REF:0000033, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000033, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037} O75027 ATP-binding cassette sub-family B member 7, mitochondrial protein 20130413 {GO:0006879=IBA, GO:0005739=IDA, GO:0015886=TAS, GO:0005737=IDA, GO:0015232=TAS, GO:0006810=TAS, GO:0005743=TAS, GO:0042626=IBA, GO:0044281=TAS, GO:0016021=IBA, GO:0055085=TAS, GO:0005524=IEA} cellular iron ion homeostasis, heme transport, small molecule metabolic process, transmembrane transport, transport cytoplasm, integral to membrane, mitochondrial inner membrane, mitochondrion ATP binding, ATPase activity, coupled to transmembrane movement of substances, heme transporter activity Human ABCB8 HPA UniProtKB {GO:0005215=PMID:9878413, GO:0005730=GO_REF:0000052, GO:0005743=GO_REF:0000039, GO:0042626=GO_REF:0000033, GO:0005634=GO_REF:0000052, GO:0005740=PMID:9878413, GO:0005524=GO_REF:0000037, GO:0055085=GO_REF:0000033, GO:0005739=GO_REF:0000052, GO:0016020=PMID:9878413, GO:0006810=PMID:9878413, GO:0016021=GO_REF:0000033, GO:0043190=PMID:9878413} Q9NUT2 ATP-binding cassette sub-family B member 8, mitochondrial protein 20111111 {GO:0005215=TAS, GO:0005730=IDA, GO:0005743=IEA, GO:0042626=IBA, GO:0005634=IDA, GO:0005740=TAS, GO:0005524=IEA, GO:0055085=IBA, GO:0005739=IDA, GO:0016020=TAS, GO:0006810=TAS, GO:0016021=IBA, GO:0043190=TAS} transmembrane transport, transport ATP-binding cassette (ABC) transporter complex, integral to membrane, membrane, mitochondrial envelope, mitochondrial inner membrane, mitochondrion, nucleolus, nucleus ATP binding, ATPase activity, coupled to transmembrane movement of substances, transporter activity Human ABCB9 UniProtKB UniProtKB {GO:0002474=PMID:17977821, GO:0042288=GO_REF:0000033, GO:0042825=GO_REF:0000033, GO:0005886=GO_REF:0000033, GO:0005783=PMID:17977821, GO:0046980=GO_REF:0000033, GO:0005743=GO_REF:0000033, GO:0042626=GO_REF:0000002, GO:0030176=PMID:11011155, GO:0005765=PMID:17977821, GO:0015031=GO_REF:0000037, GO:0055085=GO_REF:0000033, GO:0005524=PMID:15863492, GO:0042803=PMID:18952056, GO:0015833=PMID:17977821, GO:0022891=PMID:18434309, GO:0001916=GO_REF:0000033, GO:0042605=GO_REF:0000033, GO:0016021=PMID:18434309, GO:0046978=GO_REF:0000033, GO:0015440=PMID:17977821, GO:0046979=GO_REF:0000033, GO:0005769=PMID:17977821, GO:0015421=GO_REF:0000033} Q9NP78 ATP-binding cassette sub-family B member 9 protein 20100212 {GO:0002474=IDA, GO:0042288=IBA, GO:0042825=IBA, GO:0005886=IBA, GO:0005783=IDA, GO:0046980=IBA, GO:0005743=IRD, GO:0042626=IEA, GO:0030176=IDA, GO:0005765=IDA, GO:0015031=IEA, GO:0055085=IBA, GO:0005524=IDA, GO:0042803=IPI, GO:0015833=IDA, GO:0022891=IDA, GO:0001916=IBA, GO:0042605=IBA, GO:0016021=IDA, GO:0046978=IBA, GO:0015440=IDA, GO:0046979=IBA, GO:0005769=IDA, GO:0015421=IBA} antigen processing and presentation of peptide antigen via MHC class I, peptide transport, positive regulation of T cell mediated cytotoxicity, protein transport, transmembrane transport TAP complex, early endosome, endoplasmic reticulum, integral to endoplasmic reticulum membrane, integral to membrane, lysosomal membrane, mitochondrial inner membrane, plasma membrane ATP binding, ATPase activity, coupled to transmembrane movement of substances, MHC class I protein binding, TAP1 binding, TAP2 binding, oligopeptide-transporting ATPase activity, peptide antigen binding, peptide-transporting ATPase activity, protein homodimerization activity, substrate-specific transmembrane transporter activity, tapasin binding Human UniProtKB:Q9NP78 ABCC1 GOC UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0005215=PMID:1360704, GO:0005794=GO_REF:0000052, GO:0006200=PMID:15999530, GO:0005886=GO_REF:0000052, GO:0042493=PMID:1360704, GO:0005730=GO_REF:0000052, GO:0042626=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0006691=Reactome:REACT_150420, GO:0016020=PMID:1360704, GO:0005887=GO_REF:0000019, GO:0006810=PMID:1360704, GO:0016021=GO_REF:0000002, GO:0016887=PMID:15999530} P33527 Multidrug resistance-associated protein 1 protein 20130413 {GO:0019369=TAS, GO:0005215=TAS, GO:0005794=IDA, GO:0006200=IDA, GO:0005886=IDA, GO:0042493=TAS, GO:0005730=IDA, GO:0042626=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0055085=TAS, GO:0005524=IEA, GO:0006691=TAS, GO:0016020=TAS, GO:0005887=IEA, GO:0006810=TAS, GO:0016021=IEA, GO:0016887=IDA} ATP catabolic process, arachidonic acid metabolic process, leukotriene metabolic process, response to drug, small molecule metabolic process, transmembrane transport, transport Golgi apparatus, integral to membrane, integral to plasma membrane, membrane, nucleolus, nucleus, plasma membrane ATP binding, ATPase activity, ATPase activity, coupled to transmembrane movement of substances, transporter activity Human ABCC10 Reactome UniProtKB {GO:0005886=Reactome:REACT_111162, GO:0042626=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0016887=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q5T3U5 Multidrug resistance-associated protein 7 protein 20130301 {GO:0005886=TAS, GO:0042626=IEA, GO:0016021=IEA, GO:0055085=TAS, GO:0016887=IEA, GO:0005524=IEA} transmembrane transport integral to membrane, plasma membrane ATP binding, ATPase activity, ATPase activity, coupled to transmembrane movement of substances Human ABCC12 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0042626=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q96J65 Multidrug resistance-associated protein 9 protein 20130413 {GO:0005739=IEA, GO:0042626=IEA, GO:0016021=IEA, GO:0005524=IEA} integral to membrane, mitochondrion ATP binding, ATPase activity, coupled to transmembrane movement of substances Human Ensembl:ENSMUSP00000122402 ABCC2 GOC UniProtKB {GO:0005515=PMID:21988832, GO:0016324=GO_REF:0000024, GO:0046581=GO_REF:0000019, GO:0005886=Reactome:REACT_111162, GO:0005887=GO_REF:0000019, GO:0015711=PMID:7559771, GO:0006810=PMID:7559771, GO:0042626=GO_REF:0000002, GO:0008514=PMID:7559771, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037} Q92887 Canalicular multispecific organic anion transporter 1 protein 20130413 {GO:0005515=IPI, GO:0016324=ISS, GO:0046581=IEA, GO:0005886=TAS, GO:0005887=IEA, GO:0015711=TAS, GO:0006810=TAS, GO:0042626=IEA, GO:0008514=TAS, GO:0055085=TAS, GO:0005524=IEA} organic anion transport, transmembrane transport, transport apical plasma membrane, integral to plasma membrane, intercellular canaliculus, plasma membrane ATP binding, ATPase activity, coupled to transmembrane movement of substances, organic anion transmembrane transporter activity, protein binding Human ABCC3 Reactome UniProtKB {GO:0005886=Reactome:REACT_111162, GO:0016020=PMID:9813153, GO:0005887=GO_REF:0000019, GO:0015721=Reactome:REACT_11042, GO:0006810=PMID:9813153, GO:0042626=GO_REF:0000002, GO:0008206=Reactome:REACT_11040, GO:0008514=PMID:9738950, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037} O15438 Canalicular multispecific organic anion transporter 2 protein 20130301 {GO:0005886=TAS, GO:0016020=TAS, GO:0005887=IEA, GO:0015721=TAS, GO:0006810=TAS, GO:0042626=IEA, GO:0008206=TAS, GO:0008514=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0055085=TAS, GO:0005524=IEA} bile acid and bile salt transport, bile acid metabolic process, small molecule metabolic process, transmembrane transport, transport integral to membrane, integral to plasma membrane, membrane, plasma membrane ATP binding, ATPase activity, coupled to transmembrane movement of substances, organic anion transmembrane transporter activity Human ABCC4 UniProtKB UniProtKB {GO:0031088=Reactome:REACT_23865, GO:0008150=GO_REF:0000015, GO:0016020=PMID:15297306, GO:0005886=Reactome:REACT_111162, GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0030168=Reactome:REACT_798, GO:0042626=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000038, GO:0016404=PMID:7557451} Q8IUA3 Multidrug resistance-associated protein 4 protein 20130413 {GO:0031088=TAS, GO:0008150=ND, GO:0016020=IDA, GO:0005886=TAS, GO:0007596=TAS, GO:0002576=TAS, GO:0030168=TAS, GO:0042626=IEA, GO:0016021=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0016404=NAS} biological_process, blood coagulation, platelet activation, platelet degranulation, transmembrane transport integral to membrane, membrane, plasma membrane, platelet dense granule membrane 15-hydroxyprostaglandin dehydrogenase (NAD+) activity, ATP binding, ATPase activity, coupled to transmembrane movement of substances Human UniProtKB-KW:KW-0067 ABCC5 UniProtKB UniProtKB {GO:0005886=Reactome:REACT_121051, GO:0005975=Reactome:REACT_474, GO:0042626=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000038, GO:0016020=PMID:15297306, GO:0005887=PMID:9827529, GO:0015711=PMID:9827529, GO:0006810=PMID:9827529, GO:0030213=Reactome:REACT_121301, GO:0030212=Reactome:REACT_121083, GO:0008514=PMID:9827529, GO:0016021=GO_REF:0000002, GO:0030203=Reactome:REACT_121315} Q86UX3 ATP-binding cassette C5 splicing variant A protein 20130413 {GO:0005886=TAS, GO:0005975=TAS, GO:0042626=IEA, GO:0044281=TAS, GO:0055085=TAS, GO:0005524=IEA, GO:0016020=IDA, GO:0005887=TAS, GO:0015711=TAS, GO:0006810=TAS, GO:0030213=TAS, GO:0030212=TAS, GO:0008514=TAS, GO:0016021=IEA, GO:0030203=TAS} carbohydrate metabolic process, glycosaminoglycan metabolic process, hyaluronan biosynthetic process, hyaluronan metabolic process, organic anion transport, small molecule metabolic process, transmembrane transport, transport integral to membrane, integral to plasma membrane, membrane, plasma membrane ATP binding, ATPase activity, coupled to transmembrane movement of substances, organic anion transmembrane transporter activity Human UniProtKB-KW:KW-0067 ABCC6 Reactome UniProtKB {GO:0005215=PMID:8912525, GO:0016324=GO_REF:0000019, GO:0005886=Reactome:REACT_111162, GO:0042493=PMID:8912525, GO:0006810=PMID:8912525, GO:0042626=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0016328=GO_REF:0000019, GO:0007601=GO_REF:0000037, GO:0005524=GO_REF:0000019} O95255 Multidrug resistance-associated protein 6 protein 20130301 {GO:0005215=TAS, GO:0016324=IEA, GO:0005886=TAS, GO:0042493=TAS, GO:0006810=TAS, GO:0042626=IEA, GO:0016021=IEA, GO:0055085=TAS, GO:0016328=IEA, GO:0007601=IEA, GO:0005524=IEA} response to drug, transmembrane transport, transport, visual perception apical plasma membrane, integral to membrane, lateral plasma membrane, plasma membrane ATP binding, ATPase activity, coupled to transmembrane movement of substances, transporter activity Human ABCC8 GOC UniProtKB {GO:0015079=PMID:7502040, GO:0005886=Reactome:REACT_111162, GO:0005975=PMID:7716548, GO:0008281=GO_REF:0000002, GO:0042626=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0044325=PMID:20610380, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0008076=PMID:20610380, GO:0016021=GO_REF:0000002, GO:0006813=PMID:7502040, GO:0071805=PMID:7502040} Q09428 ATP-binding cassette sub-family C member 8 protein 20130413 {GO:0015079=TAS, GO:0005886=TAS, GO:0005975=NAS, GO:0008281=IEA, GO:0042626=IEA, GO:0007268=TAS, GO:0044281=TAS, GO:0005524=IEA, GO:0055085=TAS, GO:0044325=IPI, GO:0006112=TAS, GO:0050796=TAS, GO:0008076=IDA, GO:0016021=IEA, GO:0006813=TAS, GO:0071805=TAS} carbohydrate metabolic process, energy reserve metabolic process, potassium ion transmembrane transport, potassium ion transport, regulation of insulin secretion, small molecule metabolic process, synaptic transmission, transmembrane transport integral to membrane, plasma membrane, voltage-gated potassium channel complex ATP binding, ATPase activity, coupled to transmembrane movement of substances, ion channel binding, potassium ion transmembrane transporter activity, sulfonylurea receptor activity Human ABCC9 InterPro UniProtKB {GO:0005215=PMID:8826984, GO:0005886=Reactome:REACT_111162, GO:0008282=GO_REF:0000024, GO:0008281=GO_REF:0000002, GO:0015459=GO_REF:0000024, GO:0010107=GO_REF:0000024, GO:0042626=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0005524=GO_REF:0000002, GO:0030017=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0044325=PMID:20610380, GO:0051607=PMID:18026101, GO:0016020=GO_REF:0000002, GO:0008076=PMID:20610380, GO:0016021=GO_REF:0000002, GO:0006813=GO_REF:0000002} Q8N4N7 ATP-binding cassette sub-family C member 9 protein 20130413 {GO:0005215=TAS, GO:0005886=TAS, GO:0008282=ISS, GO:0008281=IEA, GO:0015459=ISS, GO:0010107=ISS, GO:0042626=IEA, GO:0007268=TAS, GO:0005524=IEA, GO:0030017=IEA, GO:0055085=TAS, GO:0044325=IPI, GO:0051607=IMP, GO:0016020=IEA, GO:0008076=IDA, GO:0016021=IEA, GO:0006813=IEA} defense response to virus, potassium ion import, potassium ion transport, synaptic transmission, transmembrane transport ATP-sensitive potassium channel complex, integral to membrane, membrane, plasma membrane, sarcomere, voltage-gated potassium channel complex ATP binding, ATPase activity, coupled to transmembrane movement of substances, ion channel binding, potassium channel regulator activity, sulfonylurea receptor activity, transporter activity Human InterPro:IPR000388 ABCD1 GOC UniProtKB {GO:0005515=PMID:10551832, GO:0005215=PMID:8441467, GO:0006200=PMID:11248239, GO:0042626=PMID:8441467, GO:0044281=Reactome:REACT_111217, GO:0042803=PMID:17609205, GO:0042802=PMID:10551832, GO:0005829=Reactome:REACT_15396, GO:0005739=GO_REF:0000019, GO:0015910=PMID:18757502, GO:0006810=GO_REF:0000002, GO:0007031=PMID:8441467, GO:0015919=PMID:8441467, GO:0016887=PMID:11248239, GO:0005779=PMID:8441467, GO:0044255=Reactome:REACT_16957, GO:0042760=PMID:9425230, GO:0005778=Reactome:REACT_121197, GO:0005777=PMID:10777694, GO:0006635=PMID:21145416, GO:0005325=Reactome:REACT_16917, GO:0036109=Reactome:REACT_121147, GO:0055085=Reactome:REACT_15518, GO:0005524=PMID:11248239, GO:0033559=Reactome:REACT_121284, GO:0043651=Reactome:REACT_121100, GO:0016020=GO_REF:0000002, GO:0042758=PMID:18757502, GO:0033540=Reactome:REACT_17062, GO:0019899=PMID:16781659} P33897 ATP-binding cassette sub-family D member 1 protein 20130413 {GO:0005515=IPI, GO:0005215=NAS, GO:0006200=IDA, GO:0042626=NAS, GO:0044281=TAS, GO:0042803=IDA, GO:0042802=IPI, GO:0005829=TAS, GO:0005739=IEA, GO:0015910=IGI, GO:0006810=IEA, GO:0007031=NAS, GO:0015919=NAS, GO:0016887=IDA, GO:0005779=NAS, GO:0044255=TAS, GO:0042760=IDA, GO:0005778=TAS, GO:0005777=IDA, GO:0006635=IGI, GO:0005325=TAS, GO:0036109=TAS, GO:0055085=TAS, GO:0005524=IDA, GO:0033559=TAS, GO:0043651=TAS, GO:0016020=IEA, GO:0042758=IGI, GO:0033540=TAS, GO:0019899=IPI} ATP catabolic process, alpha-linolenic acid metabolic process, cellular lipid metabolic process, fatty acid beta-oxidation, fatty acid beta-oxidation using acyl-CoA oxidase, linoleic acid metabolic process, long-chain fatty acid catabolic process, peroxisomal long-chain fatty acid import, peroxisomal membrane transport, peroxisome organization, small molecule metabolic process, transmembrane transport, transport, unsaturated fatty acid metabolic process, very long-chain fatty acid catabolic process cytosol, integral to peroxisomal membrane, membrane, mitochondrion, peroxisomal membrane, peroxisome ATP binding, ATPase activity, ATPase activity, coupled to transmembrane movement of substances, enzyme binding, identical protein binding, peroxisomal fatty-acyl-CoA transporter activity, protein binding, protein homodimerization activity, transporter activity Human ABCD2 HPA UniProtKB {GO:0005515=PMID:10777694, GO:0006635=PMID:21145416, GO:0005524=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0042803=PMID:21145416, GO:0043231=GO_REF:0000052, GO:0005829=Reactome:REACT_15396, GO:0005739=GO_REF:0000019, GO:0032000=PMID:10196381, GO:0016021=GO_REF:0000037, GO:0016887=GO_REF:0000002, GO:0042760=PMID:21145416, GO:0005778=Reactome:REACT_15396, GO:0005777=PMID:21145416} Q9UBJ2 ATP-binding cassette sub-family D member 2 protein 20110516 {GO:0005515=IPI, GO:0006635=IGI, GO:0005524=IEA, GO:0055085=TAS, GO:0042803=IDA, GO:0043231=IDA, GO:0005829=TAS, GO:0005739=IEA, GO:0032000=IDA, GO:0016021=IEA, GO:0016887=IEA, GO:0042760=IGI, GO:0005778=TAS, GO:0005777=IDA} fatty acid beta-oxidation, positive regulation of fatty acid beta-oxidation, transmembrane transport, very long-chain fatty acid catabolic process cytosol, integral to membrane, intracellular membrane-bounded organelle, mitochondrion, peroxisomal membrane, peroxisome ATP binding, ATPase activity, protein binding, protein homodimerization activity Human ABCD3 GOC UniProtKB {GO:0005515=PMID:14709540, GO:0006200=PMID:11248239, GO:0005782=PMID:9765053, GO:0005743=GO_REF:0000019, GO:0042626=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0005524=PMID:11248239, GO:0042803=PMID:17609205, GO:0005829=Reactome:REACT_15396, GO:0043231=GO_REF:0000052, GO:0006810=GO_REF:0000002, GO:0007031=PMID:9765053, GO:0016021=GO_REF:0000037, GO:0016887=PMID:11248239, GO:0042760=PMID:9425230, GO:0005778=Reactome:REACT_15396, GO:0005777=PMID:9922452} P28288 ATP-binding cassette sub-family D member 3 protein 20130413 {GO:0005515=IPI, GO:0006200=IDA, GO:0005782=IDA, GO:0005743=IEA, GO:0042626=IEA, GO:0055085=TAS, GO:0005524=IDA, GO:0042803=IDA, GO:0005829=TAS, GO:0043231=IDA, GO:0006810=IEA, GO:0007031=IMP, GO:0016021=IEA, GO:0016887=IDA, GO:0042760=IGI, GO:0005778=TAS, GO:0005777=IDA} ATP catabolic process, peroxisome organization, transmembrane transport, transport, very long-chain fatty acid catabolic process cytosol, integral to membrane, intracellular membrane-bounded organelle, mitochondrial inner membrane, peroxisomal matrix, peroxisomal membrane, peroxisome ATP binding, ATPase activity, ATPase activity, coupled to transmembrane movement of substances, protein binding, protein homodimerization activity Human ABCD4 UniProtKB UniProtKB {GO:0009235=PMID:22922874, GO:0016020=GO_REF:0000002, GO:0005789=GO_REF:0000019, GO:0006810=GO_REF:0000002, GO:0042626=PMID:9266848, GO:0016021=PMID:9266848, GO:0043190=PMID:9266848, GO:0055085=PMID:9266848, GO:0005524=PMID:9266848, GO:0016887=GO_REF:0000002, GO:0005778=GO_REF:0000039, GO:0005777=PMID:14533738} O14678 ATP-binding cassette sub-family D member 4 protein 20120426 {GO:0009235=IMP, GO:0016020=IEA, GO:0005789=IEA, GO:0006810=IEA, GO:0042626=NAS, GO:0016021=NAS, GO:0043190=NAS, GO:0055085=NAS, GO:0005524=NAS, GO:0016887=IEA, GO:0005778=IEA, GO:0005777=IDA} cobalamin metabolic process, transmembrane transport, transport ATP-binding cassette (ABC) transporter complex, endoplasmic reticulum membrane, integral to membrane, membrane, peroxisomal membrane, peroxisome ATP binding, ATPase activity, ATPase activity, coupled to transmembrane movement of substances Human ABCE1 PINC UniProtKB {GO:0005739=PMID:11585831, GO:0005737=PMID:11585831, GO:0051539=GO_REF:0000038, GO:0008428=PMID:7539425, GO:0051536=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0009055=GO_REF:0000002, GO:0009615=PMID:7539425, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002, GO:0046872=GO_REF:0000038, GO:0006401=PMID:7539425} P61221 ATP-binding cassette sub-family E member 1 protein 20061116 {GO:0005739=IDA, GO:0005737=IDA, GO:0051539=IEA, GO:0008428=TAS, GO:0051536=IEA, GO:0019048=IEA, GO:0009055=IEA, GO:0009615=TAS, GO:0005524=IEA, GO:0016887=IEA, GO:0046872=IEA, GO:0006401=TAS} RNA catabolic process, response to virus, virus-host interaction cytoplasm, mitochondrion 4 iron, 4 sulfur cluster binding, ATP binding, ATPase activity, electron carrier activity, iron-sulfur cluster binding, metal ion binding, ribonuclease inhibitor activity Human ABCF1 PINC UniProtKB {GO:0005515=PMID:17894550, GO:0006954=PMID:9790762, GO:0005840=GO_REF:0000019, GO:0005654=GO_REF:0000039, GO:0005635=GO_REF:0000039, GO:0006412=PMID:9790762, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002, GO:0008135=PMID:9790762} Q8NE71 ATP-binding cassette sub-family F member 1 protein 20050308 {GO:0005515=IPI, GO:0006954=TAS, GO:0005840=IEA, GO:0005654=IEA, GO:0005635=IEA, GO:0006412=TAS, GO:0005524=IEA, GO:0016887=IEA, GO:0008135=TAS} inflammatory response, translation nuclear envelope, nucleoplasm, ribosome ATP binding, ATPase activity, protein binding, translation factor activity, nucleic acid binding Human ABCF2 PINC UniProtKB {GO:0005739=GO_REF:0000019, GO:0005215=PMID:9878413, GO:0006810=PMID:9878413, GO:0005740=PMID:9878413, GO:0043190=PMID:9878413, GO:0016887=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q9UG63 ATP-binding cassette sub-family F member 2 protein 20030904 {GO:0005739=IEA, GO:0005215=TAS, GO:0006810=TAS, GO:0005740=TAS, GO:0043190=TAS, GO:0016887=IEA, GO:0005524=IEA} transport ATP-binding cassette (ABC) transporter complex, mitochondrial envelope, mitochondrion ATP binding, ATPase activity, transporter activity Human ABCF3 UniProtKB UniProtKB {GO:0051607=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002} Q9NUQ8 ATP-binding cassette sub-family F member 3 protein 20130413 {GO:0051607=IEA, GO:0005524=IEA, GO:0016887=IEA} defense response to virus ATP binding, ATPase activity Human UniProtKB-KW:KW-0051 ABCG1 GOC UniProtKB {GO:0019534=PMID:17408620, GO:0042803=PMID:16870176, GO:0046983=PMID:11500512, GO:0006810=GO_REF:0000002, GO:0042632=PMID:15994327, GO:0033344=PMID:15994327, GO:0005794=PMID:16780588, GO:0046982=PMID:16870176, GO:0010745=PMID:18490524, GO:0043691=GO_REF:0000024, GO:0005548=PMID:16702602, GO:0055099=GO_REF:0000019, GO:0043531=PMID:16702602, GO:0034374=PMID:16556852, GO:0005887=PMID:11500512, GO:0034375=PMID:16556852, GO:0042157=Reactome:REACT_13621, GO:0005789=GO_REF:0000039, GO:0055091=PMID:16702602, GO:0034436=PMID:17293612, GO:0034437=PMID:17293612, GO:0045542=GO_REF:0000024, GO:0032367=PMID:15994327, GO:0009897=PMID:16556852, GO:0006629=Reactome:REACT_602, GO:0005886=Reactome:REACT_13681, GO:0017127=PMID:15994327, GO:0033993=PMID:16556852, GO:0010872=PMID:16556852, GO:0044281=Reactome:REACT_111217, GO:0010875=GO_REF:0000019, GO:0005739=PMID:22042635, GO:0005543=PMID:16702602, GO:0015485=PMID:15994327, GO:0016887=GO_REF:0000002, GO:1901998=PMID:17408620, GO:0009720=PMID:11500512, GO:0008203=PMID:15994327, GO:0042987=PMID:17293612, GO:0006355=GO_REF:0000024, GO:0010033=PMID:11500512, GO:0055085=Reactome:REACT_15518, GO:0005524=PMID:16702602, GO:0010887=PMID:18490524, GO:0033700=PMID:16702602, GO:0000139=GO_REF:0000039, GO:0034041=PMID:17408620, GO:0016021=GO_REF:0000002, GO:0055037=PMID:16556852, GO:0005768=GO_REF:0000024} P45844 ATP-binding cassette sub-family G member 1 protein 20130413 {GO:0019534=IDA, GO:0042803=IDA, GO:0046983=NAS, GO:0006810=IEA, GO:0042632=IDA, GO:0033344=IDA, GO:0005794=IDA, GO:0046982=IPI, GO:0010745=TAS, GO:0043691=ISS, GO:0005548=IDA, GO:0055099=IEA, GO:0043531=IDA, GO:0034374=ISS, GO:0005887=IC, GO:0034375=ISS, GO:0042157=TAS, GO:0005789=IEA, GO:0055091=IMP, GO:0034436=IDA, GO:0034437=IDA, GO:0045542=ISS, GO:0032367=IMP, GO:0009897=IDA, GO:0006629=TAS, GO:0005886=TAS, GO:0017127=IDA, GO:0033993=IDA, GO:0010872=ISS, GO:0044281=TAS, GO:0010875=IEA, GO:0005739=IDA, GO:0005543=IC, GO:0015485=IC, GO:0016887=IEA, GO:1901998=IDA, GO:0009720=NAS, GO:0008203=IDA, GO:0042987=IDA, GO:0006355=ISS, GO:0010033=IDA, GO:0055085=TAS, GO:0005524=IDA, GO:0010887=TAS, GO:0033700=IMP, GO:0000139=IEA, GO:0034041=IDA, GO:0016021=IEA, GO:0055037=ISS, GO:0005768=ISS} amyloid precursor protein catabolic process, cholesterol efflux, cholesterol homeostasis, cholesterol metabolic process, detection of hormone stimulus, glycoprotein transport, high-density lipoprotein particle remodeling, intracellular cholesterol transport, lipid metabolic process, lipoprotein metabolic process, low-density lipoprotein particle remodeling, negative regulation of cholesterol storage, negative regulation of macrophage derived foam cell differentiation, phospholipid efflux, phospholipid homeostasis, positive regulation of cholesterol biosynthetic process, positive regulation of cholesterol efflux, regulation of cholesterol esterification, regulation of transcription, DNA-dependent, response to high density lipoprotein particle stimulus, response to lipid, response to organic substance, reverse cholesterol transport, small molecule metabolic process, toxin transport, transmembrane transport, transport Golgi apparatus, Golgi membrane, endoplasmic reticulum membrane, endosome, external side of plasma membrane, integral to membrane, integral to plasma membrane, mitochondrion, plasma membrane, recycling endosome ADP binding, ATP binding, ATPase activity, cholesterol binding, cholesterol transporter activity, glycoprotein transporter activity, phospholipid binding, phospholipid transporter activity, protein dimerization activity, protein heterodimerization activity, protein homodimerization activity, sterol-transporting ATPase activity, toxin transporter activity Human ABCG2 GOC UniProtKB {GO:0015886=Reactome:REACT_25155, GO:0005215=PMID:9861027, GO:0005886=Reactome:REACT_25155, GO:0015232=Reactome:REACT_25155, GO:0042493=PMID:9861027, GO:0042626=PMID:9850061, GO:0044281=Reactome:REACT_111217, GO:0046415=PMID:19503597, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0042803=PMID:16870176, GO:0006879=Reactome:REACT_25060, GO:0008559=PMID:9861027, GO:0006855=Reactome:REACT_120801, GO:0006810=PMID:9850061, GO:0016021=GO_REF:0000037} Q9UNQ0 ATP-binding cassette sub-family G member 2 protein 20130413 {GO:0015886=TAS, GO:0005215=TAS, GO:0005886=TAS, GO:0015232=TAS, GO:0042493=TAS, GO:0042626=TAS, GO:0044281=TAS, GO:0046415=IMP, GO:0055085=TAS, GO:0005524=IEA, GO:0042803=IDA, GO:0006879=TAS, GO:0008559=TAS, GO:0006855=TAS, GO:0006810=TAS, GO:0016021=IEA} cellular iron ion homeostasis, drug transmembrane transport, heme transport, response to drug, small molecule metabolic process, transmembrane transport, transport, urate metabolic process integral to membrane, plasma membrane ATP binding, ATPase activity, coupled to transmembrane movement of substances, heme transporter activity, protein homodimerization activity, transporter activity, xenobiotic-transporting ATPase activity Human ABCG4 BHF-UCL UniProtKB {GO:0033344=PMID:16682745, GO:0046982=PMID:16870176, GO:0005886=Reactome:REACT_111034, GO:0017127=Reactome:REACT_111034, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0016887=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0042803=PMID:16870176} Q9H172 ATP-binding cassette sub-family G member 4 protein 20090507 {GO:0033344=TAS, GO:0046982=IPI, GO:0005886=TAS, GO:0017127=TAS, GO:0016021=IEA, GO:0055085=TAS, GO:0016887=IEA, GO:0005524=IEA, GO:0042803=IDA} cholesterol efflux, transmembrane transport integral to membrane, plasma membrane ATP binding, ATPase activity, cholesterol transporter activity, protein heterodimerization activity, protein homodimerization activity Human ABCG5 GOC UniProtKB {GO:0042632=PMID:11099417, GO:0005515=PMID:17474147, GO:0006629=Reactome:REACT_602, GO:0007588=PMID:14504269, GO:0033344=PMID:14504269, GO:0006200=PMID:16893193, GO:0046982=PMID:16870176, GO:0005886=Reactome:REACT_13440, GO:0007584=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0017127=PMID:14504269, GO:0044281=Reactome:REACT_111217, GO:0045796=PMID:11099417, GO:0055085=Reactome:REACT_15518, GO:0005524=PMID:16893193, GO:0030299=PMID:12208868, GO:0016324=PMID:14504269, GO:0016020=GO_REF:0000002, GO:0010949=PMID:11099417, GO:0010212=GO_REF:0000019, GO:0015918=Reactome:REACT_13781, GO:0016021=GO_REF:0000037, GO:0016887=PMID:16893193} Q9H222 ATP-binding cassette sub-family G member 5 protein 20130413 {GO:0042632=IMP, GO:0005515=IPI, GO:0006629=TAS, GO:0007588=IGI, GO:0033344=IGI, GO:0006200=IDA, GO:0046982=IPI, GO:0005886=TAS, GO:0007584=IEA, GO:0042493=IEA, GO:0017127=IGI, GO:0044281=TAS, GO:0045796=IMP, GO:0055085=TAS, GO:0005524=IDA, GO:0030299=IC, GO:0016324=IMP, GO:0016020=IEA, GO:0010949=IMP, GO:0010212=IEA, GO:0015918=TAS, GO:0016021=IEA, GO:0016887=IDA} ATP catabolic process, cholesterol efflux, cholesterol homeostasis, excretion, intestinal cholesterol absorption, lipid metabolic process, negative regulation of intestinal cholesterol absorption, negative regulation of intestinal phytosterol absorption, response to drug, response to ionizing radiation, response to nutrient, small molecule metabolic process, sterol transport, transmembrane transport apical plasma membrane, integral to membrane, membrane, plasma membrane ATP binding, ATPase activity, cholesterol transporter activity, protein binding, protein heterodimerization activity Human ABCG8 GOC UniProtKB {GO:0006629=Reactome:REACT_602, GO:0042632=PMID:11099417, GO:0007588=PMID:14504269, GO:0033344=PMID:14504269, GO:0006200=PMID:16893193, GO:0005886=Reactome:REACT_13440, GO:0046982=PMID:16870176, GO:0007584=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0017127=PMID:14504269, GO:0044281=Reactome:REACT_111217, GO:0055085=Reactome:REACT_15518, GO:0045796=PMID:11099417, GO:0005524=PMID:16893193, GO:0030299=PMID:12208868, GO:0016324=PMID:14504269, GO:0015914=GO_REF:0000019, GO:0010949=PMID:11099417, GO:0015918=Reactome:REACT_13781, GO:0016021=GO_REF:0000037, GO:0016887=PMID:16893193} Q9H221 ATP-binding cassette sub-family G member 8 protein 20130413 {GO:0006629=TAS, GO:0042632=IMP, GO:0007588=IGI, GO:0033344=IGI, GO:0006200=IDA, GO:0005886=TAS, GO:0046982=IPI, GO:0007584=IEA, GO:0042493=IEA, GO:0017127=IGI, GO:0044281=TAS, GO:0055085=TAS, GO:0045796=IMP, GO:0005524=IDA, GO:0030299=IC, GO:0016324=IMP, GO:0015914=IEA, GO:0010949=IMP, GO:0015918=TAS, GO:0016021=IEA, GO:0016887=IDA} ATP catabolic process, cholesterol efflux, cholesterol homeostasis, excretion, intestinal cholesterol absorption, lipid metabolic process, negative regulation of intestinal cholesterol absorption, negative regulation of intestinal phytosterol absorption, phospholipid transport, response to drug, response to nutrient, small molecule metabolic process, sterol transport, transmembrane transport apical plasma membrane, integral to membrane, plasma membrane ATP binding, ATPase activity, cholesterol transporter activity, protein heterodimerization activity Human ABHD10 BHF-UCL UniProtKB {GO:0005739=GO_REF:0000054, GO:0016787=GO_REF:0000038, GO:0005829=PMID:22294686} Q9NUJ1 Mycophenolic acid acyl-glucuronide esterase, mitochondrial protein 20120510 {GO:0005739=IDA, GO:0016787=IEA, GO:0005829=IDA} cytosol, mitochondrion hydrolase activity Human ABHD11 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0016787=GO_REF:0000037, GO:0005575=GO_REF:0000015} Q8NFV4 Alpha/beta hydrolase domain-containing protein 11 protein 20080407 {GO:0005739=IEA, GO:0008150=ND, GO:0003674=ND, GO:0016787=IEA, GO:0005575=ND} biological_process cellular_component, mitochondrion hydrolase activity, molecular_function Human ABHD12 UniProtKB UniProtKB {GO:0047372=GO_REF:0000003, GO:0016021=GO_REF:0000037} Q8N2K0 Monoacylglycerol lipase ABHD12 protein 20130413 {GO:0047372=IEA, GO:0016021=IEA} integral to membrane acylglycerol lipase activity Human EC:3.1.1.23 ABHD14A UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0016787=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q9BUJ0 Alpha/beta hydrolase domain-containing protein 14A protein 20130413 {GO:0005737=IEA, GO:0016787=IEA, GO:0016021=IEA} cytoplasm, integral to membrane hydrolase activity Human UniProtKB-SubCell:SL-0086 ABHD14B HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0016787=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q96IU4 Alpha/beta hydrolase domain-containing protein 14B protein 20110516 {GO:0005737=IDA, GO:0016787=IEA, GO:0005730=IDA, GO:0005634=IDA} cytoplasm, nucleolus, nucleus hydrolase activity Human ABHD16A UniProtKB UniProtKB {GO:0016787=GO_REF:0000037, GO:0016021=GO_REF:0000037} O95870 Abhydrolase domain-containing protein 16A protein 20130413 {GO:0016787=IEA, GO:0016021=IEA} integral to membrane hydrolase activity Human UniProtKB-KW:KW-0378 ABHD2 UniProtKB UniProtKB {GO:0004091=GO_REF:0000037, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0030336=GO_REF:0000019, GO:0009611=GO_REF:0000019, GO:0016021=GO_REF:0000029} P08910 Abhydrolase domain-containing protein 2 protein 20060502 {GO:0004091=IEA, GO:0003674=ND, GO:0008150=ND, GO:0030336=IEA, GO:0009611=IEA, GO:0016021=NAS} biological_process, negative regulation of cell migration, response to wounding integral to membrane carboxylesterase activity, molecular_function Human ABHD3 UniProtKB UniProtKB {GO:0004091=GO_REF:0000037, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0016787=GO_REF:0000038, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} Q8WU67 Abhydrolase domain-containing protein 3 protein 20080407 {GO:0004091=IEA, GO:0008150=ND, GO:0003674=ND, GO:0016787=IEA, GO:0005575=ND, GO:0016021=IEA} biological_process cellular_component, integral to membrane carboxylesterase activity, hydrolase activity, molecular_function Human ABHD4 UniProtKB UniProtKB {GO:0016042=GO_REF:0000037, GO:0016787=GO_REF:0000037} Q8TB40 Abhydrolase domain-containing protein 4 protein 20130413 {GO:0016042=IEA, GO:0016787=IEA} lipid catabolic process hydrolase activity Human UniProtKB-KW:KW-0378 ABHD5 Reactome UniProtKB {GO:0005811=GO_REF:0000024, GO:0006629=Reactome:REACT_602, GO:0042171=PMID:18606822, GO:0004806=GO_REF:0000024, GO:0010898=PMID:16679289, GO:0044281=Reactome:REACT_111217, GO:0003841=GO_REF:0000003, GO:0030154=GO_REF:0000037, GO:0005829=GO_REF:0000024, GO:0010891=PMID:16679289, GO:0006508=GO_REF:0000002, GO:0006631=GO_REF:0000037, GO:0008233=GO_REF:0000002, GO:0019433=Reactome:REACT_494, GO:0006654=PMID:18606822, GO:0051006=GO_REF:0000019} Q8WTS1 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 protein 20130213 {GO:0005811=ISS, GO:0006629=TAS, GO:0042171=IDA, GO:0004806=ISS, GO:0010898=IDA, GO:0044281=TAS, GO:0003841=IEA, GO:0030154=IEA, GO:0005829=ISS, GO:0010891=IDA, GO:0006508=IEA, GO:0006631=IEA, GO:0008233=IEA, GO:0019433=TAS, GO:0006654=IDA, GO:0051006=IEA} cell differentiation, fatty acid metabolic process, lipid metabolic process, negative regulation of sequestering of triglyceride, phosphatidic acid biosynthetic process, positive regulation of lipoprotein lipase activity, positive regulation of triglyceride catabolic process, proteolysis, small molecule metabolic process, triglyceride catabolic process cytosol, lipid particle 1-acylglycerol-3-phosphate O-acyltransferase activity, lysophosphatidic acid acyltransferase activity, peptidase activity, triglyceride lipase activity Human ABHD6 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0030336=GO_REF:0000019, GO:0047372=GO_REF:0000003, GO:0016021=GO_REF:0000037, GO:0060292=GO_REF:0000019, GO:2000124=GO_REF:0000019} Q9BV23 Monoacylglycerol lipase ABHD6 protein 20130413 {GO:0005739=IEA, GO:0030336=IEA, GO:0047372=IEA, GO:0016021=IEA, GO:0060292=IEA, GO:2000124=IEA} long term synaptic depression, negative regulation of cell migration, regulation of endocannabinoid signaling pathway integral to membrane, mitochondrion acylglycerol lipase activity Human Ensembl:ENSMUSP00000129169 ABHD8 UniProtKB UniProtKB {GO:0016787=GO_REF:0000037} Q96I13 Abhydrolase domain-containing protein 8 protein 20130413 {GO:0016787=IEA} hydrolase activity Human UniProtKB-KW:KW-0378 ABI1 IntAct UniProtKB {GO:0008092=PMID:9593709, GO:0005515=PMID:21078624, GO:0008285=PMID:9010225, GO:0030054=GO_REF:0000037, GO:0005783=PMID:9593709, GO:0001756=GO_REF:0000019, GO:0045202=GO_REF:0000037, GO:0006928=PMID:11516653, GO:0018108=PMID:17101133, GO:0005634=GO_REF:0000039, GO:0030175=PMID:11516653, GO:0030027=PMID:17101133, GO:0005829=Reactome:REACT_160291, GO:0030426=GO_REF:0000039, GO:0005622=PMID:17101133, GO:0005737=GO_REF:0000002, GO:0030296=GO_REF:0000019, GO:0008154=PMID:11516653, GO:0045087=Reactome:REACT_6802, GO:0005856=GO_REF:0000039, GO:0038096=Reactome:REACT_160123, GO:0007169=PMID:9010225} Q8IZP0 Abl interactor 1 protein 20130415 {GO:0008092=TAS, GO:0005515=IPI, GO:0008285=TAS, GO:0030054=IEA, GO:0005783=TAS, GO:0001756=IEA, GO:0045202=IEA, GO:0006928=IDA, GO:0018108=IDA, GO:0005634=IEA, GO:0030175=IDA, GO:0030027=IDA, GO:0005829=TAS, GO:0030426=IEA, GO:0005622=IDA, GO:0005737=IEA, GO:0030296=IEA, GO:0008154=NAS, GO:0045087=TAS, GO:0005856=IEA, GO:0038096=TAS, GO:0007169=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, actin polymerization or depolymerization, cellular component movement, innate immune response, negative regulation of cell proliferation, peptidyl-tyrosine phosphorylation, somitogenesis, transmembrane receptor protein tyrosine kinase signaling pathway cell junction, cytoplasm, cytoskeleton, cytosol, endoplasmic reticulum, filopodium, growth cone, intracellular, lamellipodium, nucleus, synapse cytoskeletal protein binding, protein binding, protein tyrosine kinase activator activity Human UniProtKB:O00555 ABI2 BHF-UCL UniProtKB {GO:0017124=PMID:7590236, GO:0006928=PMID:11516653, GO:0018108=PMID:17101133, GO:0030175=PMID:11516653, GO:0003677=PMID:7590236, GO:0030027=PMID:11516653, GO:0016358=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0005829=PMID:18632609, GO:0005737=PMID:8649853, GO:0005913=GO_REF:0000019, GO:0016477=PMID:12011975, GO:0008154=PMID:11516653, GO:0007010=PMID:12011975, GO:0007611=GO_REF:0000019, GO:0043010=GO_REF:0000019, GO:0005856=GO_REF:0000039, GO:0019900=PMID:8649853, GO:0070064=PMID:7590236, GO:0031625=PMID:18632609, GO:0008093=PMID:12011975} Q9NYB9 Abl interactor 2 protein 20110401 {GO:0017124=IPI, GO:0006928=IDA, GO:0018108=IDA, GO:0030175=IDA, GO:0003677=TAS, GO:0030027=IDA, GO:0016358=IEA, GO:0030425=IEA, GO:0005829=IDA, GO:0005737=TAS, GO:0005913=IEA, GO:0016477=TAS, GO:0008154=NAS, GO:0007010=TAS, GO:0007611=IEA, GO:0043010=IEA, GO:0005856=IEA, GO:0019900=NAS, GO:0070064=IPI, GO:0031625=IPI, GO:0008093=TAS} actin polymerization or depolymerization, camera-type eye development, cell migration, cellular component movement, cytoskeleton organization, dendrite development, learning or memory, peptidyl-tyrosine phosphorylation cell-cell adherens junction, cytoplasm, cytoskeleton, cytosol, dendrite, filopodium, lamellipodium DNA binding, SH3 domain binding, cytoskeletal adaptor activity, kinase binding, proline-rich region binding, ubiquitin protein ligase binding Human ABI3 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0030334=PMID:11956071, GO:0005622=PMID:17101133, GO:0005737=GO_REF:0000054, GO:0006928=PMID:11956071, GO:0018108=PMID:17101133, GO:0030027=PMID:17101133} Q9P2A4 ABI gene family member 3 protein 20130415 {GO:0005515=IPI, GO:0030334=IDA, GO:0005622=IDA, GO:0005737=IDA, GO:0006928=NAS, GO:0018108=IDA, GO:0030027=IDA} cellular component movement, peptidyl-tyrosine phosphorylation, regulation of cell migration cytoplasm, intracellular, lamellipodium protein binding Human UniProtKB:O15372 ABI3BP ENSEMBL UniProtKB {GO:0030198=GO_REF:0000019, GO:0010811=GO_REF:0000019, GO:0005518=GO_REF:0000019, GO:0005614=GO_REF:0000019, GO:0008201=GO_REF:0000019} Q7Z7G0 Target of Nesh-SH3 protein 20130413 {GO:0030198=IEA, GO:0010811=IEA, GO:0005518=IEA, GO:0005614=IEA, GO:0008201=IEA} extracellular matrix organization, positive regulation of cell-substrate adhesion interstitial matrix collagen binding, heparin binding Human Ensembl:ENSMUSP00000036257 ABL1 HPA UniProtKB {GO:0005515=PMID:12893824, GO:0051353=PMID:12893824, GO:2001020=PMID:9461559, GO:2000145=PMID:20841568, GO:0050731=PMID:15657060, GO:0030155=PMID:20841568, GO:0042692=Reactome:REACT_21303, GO:2000249=PMID:20841568, GO:0030100=PMID:20841568, GO:0007411=Reactome:REACT_18266, GO:0006298=PMID:10391249, GO:0070064=PMID:15657060, GO:0051019=PMID:11121037, GO:0031965=GO_REF:0000039, GO:0000287=PMID:9144171, GO:0018108=PMID:11121037, GO:0042770=PMID:15657060, GO:0051149=Reactome:REACT_21402, GO:0000115=PMID:8242749, GO:0045087=Reactome:REACT_6802, GO:0004515=PMID:20841568, GO:0010506=PMID:20841568, GO:0038096=Reactome:REACT_160123, GO:0017124=PMID:7590236, GO:0048471=PMID:17888034, GO:0030036=GO_REF:0000024, GO:0071901=PMID:11121037, GO:0005634=GO_REF:0000052, GO:0015629=PMID:20841568, GO:0005829=Reactome:REACT_160185, GO:0005739=GO_REF:0000039, GO:0005737=PMID:20841568, GO:0051726=GO_REF:0000019, GO:0007155=GO_REF:0000037, GO:0031252=GO_REF:0000019, GO:0006355=PMID:8242749, GO:0043065=PMID:9037071, GO:0030145=PMID:9144171, GO:0008630=PMID:20841568, GO:0006914=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0008022=PMID:11971963, GO:0005524=PMID:9144171, GO:0003677=PMID:8242749, GO:0006974=PMID:15657060, GO:0006975=PMID:18280240, GO:0003785=PMID:20841568, GO:0007596=Reactome:REACT_604, GO:0048008=GO_REF:0000019, GO:0004713=PMID:11121037, GO:0004715=PMID:9461559, GO:0006464=PMID:8242749} P00519 Tyrosine-protein kinase ABL1 protein 20101115 {GO:0005515=IPI, GO:0051353=IDA, GO:2001020=IDA, GO:2000145=TAS, GO:0050731=IDA, GO:0030155=TAS, GO:0042692=TAS, GO:2000249=TAS, GO:0030100=TAS, GO:0007411=TAS, GO:0006298=TAS, GO:0070064=IDA, GO:0051019=IPI, GO:0031965=IEA, GO:0000287=IDA, GO:0018108=IDA, GO:0042770=IDA, GO:0051149=TAS, GO:0000115=TAS, GO:0045087=TAS, GO:0004515=TAS, GO:0010506=TAS, GO:0038096=TAS, GO:0017124=IPI, GO:0048471=IDA, GO:0030036=ISS, GO:0071901=IDA, GO:0005634=IDA, GO:0015629=TAS, GO:0005829=TAS, GO:0005739=IEA, GO:0005737=TAS, GO:0051726=IEA, GO:0007155=IEA, GO:0031252=IEA, GO:0006355=TAS, GO:0043065=IDA, GO:0030145=IDA, GO:0008630=TAS, GO:0006914=IEA, GO:0005730=IDA, GO:0008022=IPI, GO:0005524=IDA, GO:0003677=NAS, GO:0006974=IDA, GO:0006975=IDA, GO:0003785=TAS, GO:0007596=TAS, GO:0048008=IEA, GO:0004713=IDA, GO:0004715=IDA, GO:0006464=NAS} DNA damage induced protein phosphorylation, Fc-gamma receptor signaling pathway involved in phagocytosis, actin cytoskeleton organization, autophagy, axon guidance, blood coagulation, cell adhesion, cellular protein modification process, innate immune response, intrinsic apoptotic signaling pathway in response to DNA damage, mismatch repair, muscle cell differentiation, negative regulation of protein serine/threonine kinase activity, peptidyl-tyrosine phosphorylation, platelet-derived growth factor receptor signaling pathway, positive regulation of apoptotic process, positive regulation of muscle cell differentiation, positive regulation of oxidoreductase activity, positive regulation of peptidyl-tyrosine phosphorylation, regulation of actin cytoskeleton reorganization, regulation of autophagy, regulation of cell adhesion, regulation of cell cycle, regulation of cell motility, regulation of endocytosis, regulation of response to DNA damage stimulus, regulation of transcription involved in S phase of mitotic cell cycle, regulation of transcription, DNA-dependent, response to DNA damage stimulus, signal transduction in response to DNA damage actin cytoskeleton, cell leading edge, cytoplasm, cytosol, mitochondrion, nuclear membrane, nucleolus, nucleus, perinuclear region of cytoplasm ATP binding, DNA binding, SH3 domain binding, actin monomer binding, magnesium ion binding, manganese ion binding, mitogen-activated protein kinase binding, nicotinate-nucleotide adenylyltransferase activity, non-membrane spanning protein tyrosine kinase activity, proline-rich region binding, protein C-terminus binding, protein binding, protein tyrosine kinase activity NOT Human ABL2 BHF-UCL UniProtKB {GO:0005515=PMID:12893824, GO:0051353=PMID:12893824, GO:0071300=PMID:17910947, GO:2000145=PMID:20841568, GO:0015629=PMID:20841568, GO:0030155=PMID:20841568, GO:0005829=Reactome:REACT_19396, GO:2000249=PMID:20841568, GO:0051015=PMID:20841568, GO:0030100=PMID:20841568, GO:0007411=Reactome:REACT_18266, GO:0007155=GO_REF:0000037, GO:0051017=GO_REF:0000019, GO:0000287=PMID:15886098, GO:0030145=PMID:15886098, GO:0018108=PMID:15886098, GO:0005524=GO_REF:0000037, GO:0003785=PMID:20841568, GO:0007165=PMID:2198571, GO:0004672=PMID:2198571, GO:0010976=PMID:17910947, GO:0010506=PMID:20841568, GO:0004713=PMID:15886098, GO:0004715=PMID:20841568, GO:0006464=PMID:2198571} P42684 Abelson tyrosine-protein kinase 2 protein 20071108 {GO:0005515=IPI, GO:0051353=IDA, GO:0071300=IMP, GO:2000145=TAS, GO:0015629=TAS, GO:0030155=TAS, GO:0005829=TAS, GO:2000249=TAS, GO:0051015=TAS, GO:0030100=TAS, GO:0007411=TAS, GO:0007155=IEA, GO:0051017=IEA, GO:0000287=IDA, GO:0030145=IDA, GO:0018108=IDA, GO:0005524=IEA, GO:0003785=TAS, GO:0007165=TAS, GO:0004672=TAS, GO:0010976=IMP, GO:0010506=TAS, GO:0004713=IDA, GO:0004715=TAS, GO:0006464=TAS} actin filament bundle assembly, axon guidance, cell adhesion, cellular protein modification process, cellular response to retinoic acid, peptidyl-tyrosine phosphorylation, positive regulation of neuron projection development, positive regulation of oxidoreductase activity, regulation of actin cytoskeleton reorganization, regulation of autophagy, regulation of cell adhesion, regulation of cell motility, regulation of endocytosis, signal transduction actin cytoskeleton, cytosol ATP binding, actin filament binding, actin monomer binding, magnesium ion binding, manganese ion binding, non-membrane spanning protein tyrosine kinase activity, protein binding, protein kinase activity, protein tyrosine kinase activity Human ABLIM1 InterPro UniProtKB {GO:0005515=PMID:16189514, GO:0005737=GO_REF:0000039, GO:0007411=Reactome:REACT_18266, GO:0045944=GO_REF:0000019, GO:0007010=GO_REF:0000002, GO:0009887=PMID:9245787, GO:0008270=GO_REF:0000002, GO:0003779=GO_REF:0000002, GO:0015629=GO_REF:0000019, GO:0007601=PMID:9245787} Q5T6N4 Actin-binding LIM protein 1 protein 20130413 {GO:0005515=IPI, GO:0005737=IEA, GO:0007411=TAS, GO:0045944=IEA, GO:0007010=IEA, GO:0009887=TAS, GO:0008270=IEA, GO:0003779=IEA, GO:0015629=IEA, GO:0007601=TAS} axon guidance, cytoskeleton organization, organ morphogenesis, positive regulation of transcription from RNA polymerase II promoter, visual perception actin cytoskeleton, cytoplasm actin binding, protein binding, zinc ion binding Human InterPro:IPR001781 ABLIM2 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0007411=Reactome:REACT_18266, GO:0045944=GO_REF:0000019, GO:0007010=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000029, GO:0003779=GO_REF:0000002, GO:0045111=GO_REF:0000052, GO:0015629=PMID:17194709, GO:0030016=GO_REF:0000019} Q6H8Q1 Actin-binding LIM protein 2 protein 20101115 {GO:0005737=IDA, GO:0007411=TAS, GO:0045944=IEA, GO:0007010=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=NAS, GO:0003779=IEA, GO:0045111=IDA, GO:0015629=IDA, GO:0030016=IEA} axon guidance, cytoskeleton organization, positive regulation of transcription from RNA polymerase II promoter actin cytoskeleton, cytoplasm, intermediate filament cytoskeleton, myofibril, nucleolus, nucleus actin binding, zinc ion binding Human ABLIM3 Reactome UniProtKB {GO:0005737=GO_REF:0000029, GO:0007411=Reactome:REACT_18266, GO:0045944=GO_REF:0000019, GO:0007010=GO_REF:0000002, GO:0003779=GO_REF:0000002, GO:0008270=GO_REF:0000029} O94929 Actin-binding LIM protein 3 protein 20130301 {GO:0005737=NAS, GO:0007411=TAS, GO:0045944=IEA, GO:0007010=IEA, GO:0003779=IEA, GO:0008270=NAS} axon guidance, cytoskeleton organization, positive regulation of transcription from RNA polymerase II promoter cytoplasm actin binding, zinc ion binding Human ABP1 MGI UniProtKB {GO:0071280=PMID:9399025, GO:0097185=PMID:16846222, GO:0005886=PMID:2217167, GO:0005272=PMID:2217167, GO:0005615=PMID:12072962, GO:0032403=PMID:19764817, GO:0042803=PMID:19764817, GO:0008144=PMID:2217167, GO:0004872=PMID:2217167, GO:0035725=PMID:2217167, GO:0008201=PMID:12072962, GO:0052600=GO_REF:0000003, GO:0046677=PMID:19764817, GO:0005777=PMID:1356107, GO:0005261=PMID:19764817, GO:0048038=PMID:12072962, GO:0005507=PMID:12072962, GO:0042493=PMID:8144586, GO:0005509=PMID:12072962, GO:0052599=GO_REF:0000003, GO:0052598=GO_REF:0000003, GO:0052597=PMID:9399025, GO:0008131=PMID:8144586, GO:0035874=PMID:9399025, GO:0071504=PMID:19764817, GO:0009308=GO_REF:0000002, GO:0008270=PMID:12072962, GO:0005923=GO_REF:0000024, GO:0055114=PMID:8144586, GO:0071420=PMID:12072962} P19801 "Amiloride-sensitive amine oxidase ""copper-containing""" protein 20060110 {GO:0071280=IDA, GO:0097185=IDA, GO:0005886=IDA, GO:0005272=TAS, GO:0005615=IDA, GO:0032403=IDA, GO:0042803=IPI, GO:0008144=IDA, GO:0004872=IDA, GO:0035725=TAS, GO:0008201=IDA, GO:0052600=IEA, GO:0046677=IDA, GO:0005777=NAS, GO:0005261=IDA, GO:0048038=IDA, GO:0005507=IDA, GO:0042493=IDA, GO:0005509=IDA, GO:0052599=IEA, GO:0052598=IEA, GO:0052597=IDA, GO:0008131=IDA, GO:0035874=IDA, GO:0071504=TAS, GO:0009308=IEA, GO:0008270=IDA, GO:0005923=ISS, GO:0055114=IDA, GO:0071420=IDA} amine metabolic process, cellular response to azide, cellular response to copper ion, cellular response to copper ion starvation, cellular response to heparin, cellular response to histamine, oxidation-reduction process, response to antibiotic, response to drug, sodium ion transmembrane transport extracellular space, peroxisome, plasma membrane, tight junction calcium ion binding, cation channel activity, copper ion binding, diamine oxidase activity, drug binding, heparin binding, histamine oxidase activity, methylputrescine oxidase activity, primary amine oxidase activity, propane-1,3-diamine oxidase activity, protein complex binding, protein homodimerization activity, quinone binding, receptor activity, sodium channel activity, zinc ion binding Human ABR Reactome UniProtKB {GO:0043314=GO_REF:0000019, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0030336=GO_REF:0000019, GO:0042472=GO_REF:0000019, GO:0030036=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0007264=Reactome:REACT_11044, GO:0035023=GO_REF:0000002, GO:0006915=Reactome:REACT_13638, GO:0097190=Reactome:REACT_13720, GO:0005829=Reactome:REACT_19216, GO:0035556=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0050766=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0007420=GO_REF:0000019, GO:0050728=GO_REF:0000019, GO:0050885=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0005089=GO_REF:0000002, GO:0030675=GO_REF:0000019, GO:0005096=PMID:8262969} Q12979 Active breakpoint cluster region-related protein protein 20130301 {GO:0043314=IEA, GO:0051056=TAS, GO:0048011=TAS, GO:0030336=IEA, GO:0042472=IEA, GO:0030036=IEA, GO:0005886=IEA, GO:0007264=TAS, GO:0035023=IEA, GO:0006915=TAS, GO:0097190=TAS, GO:0005829=TAS, GO:0035556=IEA, GO:0005622=IEA, GO:0007165=IEA, GO:0050766=IEA, GO:0005543=IEA, GO:0007420=IEA, GO:0050728=IEA, GO:0050885=IEA, GO:0032496=IEA, GO:0005089=IEA, GO:0030675=IEA, GO:0005096=TAS} actin cytoskeleton organization, apoptotic process, apoptotic signaling pathway, brain development, inner ear morphogenesis, intracellular signal transduction, negative regulation of cell migration, negative regulation of inflammatory response, negative regulation of neutrophil degranulation, neuromuscular process controlling balance, neurotrophin TRK receptor signaling pathway, positive regulation of phagocytosis, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, response to lipopolysaccharide, signal transduction, small GTPase mediated signal transduction cytosol, intracellular, plasma membrane GTPase activator activity, Rac GTPase activator activity, Rho guanyl-nucleotide exchange factor activity, phospholipid binding Human ABRA LIFEdb UniProtKB {GO:0051091=GO_REF:0000024, GO:0005886=GO_REF:0000054, GO:0045944=GO_REF:0000019, GO:0035025=GO_REF:0000024, GO:0003713=GO_REF:0000019, GO:0003779=GO_REF:0000024, GO:0015629=GO_REF:0000024, GO:0030017=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0000060=GO_REF:0000019} Q8N0Z2 Actin-binding Rho-activating protein protein 20100607 {GO:0051091=ISS, GO:0005886=IDA, GO:0045944=IEA, GO:0035025=ISS, GO:0003713=IEA, GO:0003779=ISS, GO:0015629=ISS, GO:0030017=ISS, GO:0006351=IEA, GO:0000060=IEA} positive regulation of Rho protein signal transduction, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, protein import into nucleus, translocation, transcription, DNA-dependent actin cytoskeleton, plasma membrane, sarcomere actin binding, transcription coactivator activity Human ABT1 PINC UniProtKB {GO:0005515=PMID:19299493, GO:0005667=GO_REF:0000019, GO:0021522=GO_REF:0000019, GO:0006366=GO_REF:0000019, GO:0006357=GO_REF:0000019, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0003713=PMID:10648625, GO:0005730=GO_REF:0000039, GO:0005634=PMID:10648625, GO:0003677=GO_REF:0000037} Q9ULW3 Activator of basal transcription 1 protein 20030904 {GO:0005515=IPI, GO:0005667=IEA, GO:0021522=IEA, GO:0006366=IEA, GO:0006357=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0003713=TAS, GO:0005730=IEA, GO:0005634=TAS, GO:0003677=IEA} regulation of transcription from RNA polymerase II promoter, spinal cord motor neuron differentiation, transcription from RNA polymerase II promoter nucleolus, nucleus, transcription factor complex DNA binding, RNA binding, nucleotide binding, protein binding, transcription coactivator activity Human ABTB1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0003746=GO_REF:0000037} Q969K4 Ankyrin repeat and BTB/POZ domain-containing protein 1 protein 20101115 {GO:0005737=IDA, GO:0005886=IDA, GO:0005730=IDA, GO:0003746=IEA} cytoplasm, nucleolus, plasma membrane translation elongation factor activity Human ABTB2 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0046982=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0001558=GO_REF:0000029} Q8N961 Ankyrin repeat and BTB/POZ domain-containing protein 2 protein 20061026 {GO:0003674=ND, GO:0046982=IEA, GO:0005575=ND, GO:0001558=NAS} regulation of cell growth cellular_component molecular_function, protein heterodimerization activity Human ACAA1 HPA UniProtKB {GO:0005515=PMID:18281296, GO:0000038=PMID:2318981, GO:0016747=GO_REF:0000002, GO:0006635=PMID:2882519, GO:0005782=Reactome:REACT_121028, GO:0036109=Reactome:REACT_121147, GO:0044281=Reactome:REACT_111217, GO:0033559=Reactome:REACT_121284, GO:0043231=GO_REF:0000052, GO:0008206=PMID:2318981, GO:0033540=Reactome:REACT_17062, GO:0003988=GO_REF:0000003, GO:0044255=Reactome:REACT_16957} P09110 3-ketoacyl-CoA thiolase, peroxisomal protein 20110516 {GO:0005515=IPI, GO:0000038=IMP, GO:0016747=IEA, GO:0006635=IMP, GO:0005782=TAS, GO:0036109=TAS, GO:0044281=TAS, GO:0033559=TAS, GO:0043231=IDA, GO:0008206=IMP, GO:0033540=TAS, GO:0003988=IEA, GO:0044255=TAS} alpha-linolenic acid metabolic process, bile acid metabolic process, cellular lipid metabolic process, fatty acid beta-oxidation, fatty acid beta-oxidation using acyl-CoA oxidase, small molecule metabolic process, unsaturated fatty acid metabolic process, very long-chain fatty acid metabolic process intracellular membrane-bounded organelle, peroxisomal matrix acetyl-CoA C-acyltransferase activity, protein binding, transferase activity, transferring acyl groups other than amino-acyl groups Human ACAA2 UniProtKB UniProtKB {GO:0005515=PMID:18371312, GO:0005739=PMID:18371312, GO:0006695=PMID:8241273, GO:0043066=PMID:18371312, GO:0016747=GO_REF:0000002, GO:0006631=GO_REF:0000041, GO:0005743=GO_REF:0000019, GO:0003988=PMID:8241273} P42765 3-ketoacyl-CoA thiolase, mitochondrial protein 20101215 {GO:0005515=IPI, GO:0005739=IDA, GO:0006695=NAS, GO:0043066=IDA, GO:0016747=IEA, GO:0006631=IEA, GO:0005743=IEA, GO:0003988=NAS} cholesterol biosynthetic process, fatty acid metabolic process, negative regulation of apoptotic process mitochondrial inner membrane, mitochondrion acetyl-CoA C-acyltransferase activity, protein binding, transferase activity, transferring acyl groups other than amino-acyl groups Human UniProtKB:Q12983 ACACA InterPro UniProtKB {GO:0005515=PMID:16794074, GO:0006853=Reactome:REACT_11082, GO:0016874=GO_REF:0000002, GO:0055088=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0035338=Reactome:REACT_1319, GO:2001295=GO_REF:0000041, GO:0006084=GO_REF:0000024, GO:0005524=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_147816, GO:0005739=GO_REF:0000019, GO:0031325=Reactome:REACT_2122, GO:0006112=Reactome:REACT_1505, GO:0001894=GO_REF:0000019, GO:0051289=GO_REF:0000024, GO:0019432=Reactome:REACT_1190, GO:0004075=GO_REF:0000003, GO:0006633=GO_REF:0000002, GO:0003989=GO_REF:0000002, GO:0044255=Reactome:REACT_22279, GO:0044268=GO_REF:0000019} Q59FY4 Acetyl-Coenzyme A carboxylase alpha isoform 2 variant protein 20130413 {GO:0005515=IPI, GO:0006853=TAS, GO:0016874=IEA, GO:0055088=IEA, GO:0044281=TAS, GO:0035338=TAS, GO:2001295=IEA, GO:0006084=ISS, GO:0005524=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0031325=TAS, GO:0006112=TAS, GO:0001894=IEA, GO:0051289=ISS, GO:0019432=TAS, GO:0004075=IEA, GO:0006633=IEA, GO:0003989=IEA, GO:0044255=TAS, GO:0044268=IEA} acetyl-CoA metabolic process, carnitine shuttle, cellular lipid metabolic process, energy reserve metabolic process, fatty acid biosynthetic process, lipid homeostasis, long-chain fatty-acyl-CoA biosynthetic process, malonyl-CoA biosynthetic process, multicellular organismal protein metabolic process, positive regulation of cellular metabolic process, protein homotetramerization, small molecule metabolic process, tissue homeostasis, triglyceride biosynthetic process cytosol, mitochondrion ATP binding, acetyl-CoA carboxylase activity, biotin carboxylase activity, ligase activity, metal ion binding, protein binding Human InterPro:IPR013537 ACACB HPA UniProtKB {GO:0005515=PMID:16794074, GO:0006853=Reactome:REACT_11082, GO:0044281=Reactome:REACT_111217, GO:2001295=GO_REF:0000041, GO:0005524=GO_REF:0000037, GO:0006084=PMID:20952656, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_147743, GO:0012505=GO_REF:0000039, GO:0005739=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0031325=Reactome:REACT_2122, GO:0006112=Reactome:REACT_1505, GO:0016020=GO_REF:0000037, GO:0051289=PMID:20952656, GO:0004075=GO_REF:0000003, GO:0006633=GO_REF:0000019, GO:0003989=PMID:20952656, GO:0044255=Reactome:REACT_22279} O00763 Acetyl-CoA carboxylase 2 protein 20120912 {GO:0005515=IPI, GO:0006853=TAS, GO:0044281=TAS, GO:2001295=IEA, GO:0005524=IEA, GO:0006084=IDA, GO:0046872=IEA, GO:0005829=TAS, GO:0012505=IEA, GO:0005739=IEA, GO:0005737=IDA, GO:0031325=TAS, GO:0006112=TAS, GO:0016020=IEA, GO:0051289=IDA, GO:0004075=IEA, GO:0006633=IEA, GO:0003989=IDA, GO:0044255=TAS} acetyl-CoA metabolic process, carnitine shuttle, cellular lipid metabolic process, energy reserve metabolic process, fatty acid biosynthetic process, malonyl-CoA biosynthetic process, positive regulation of cellular metabolic process, protein homotetramerization, small molecule metabolic process cytoplasm, cytosol, endomembrane system, membrane, mitochondrion ATP binding, acetyl-CoA carboxylase activity, biotin carboxylase activity, metal ion binding, protein binding Human ACAD10 UniProtKB UniProtKB {GO:0005739=PMID:21237683, GO:0016787=GO_REF:0000002, GO:0050660=GO_REF:0000002, GO:0003995=GO_REF:0000002, GO:0016627=GO_REF:0000002, GO:0016772=GO_REF:0000002} Q6JQN1 Acyl-CoA dehydrogenase family member 10 protein 20111024 {GO:0005739=NAS, GO:0016787=IEA, GO:0050660=IEA, GO:0003995=IEA, GO:0016627=IEA, GO:0016772=IEA} mitochondrion acyl-CoA dehydrogenase activity, flavin adenine dinucleotide binding, hydrolase activity, oxidoreductase activity, acting on the CH-CH group of donors, transferase activity, transferring phosphorus-containing groups Human ACAD11 HGNC UniProtKB {GO:0005739=GO_REF:0000019, GO:0017099=PMID:21237683, GO:0031966=PMID:21237683, GO:0050660=GO_REF:0000002, GO:0005634=PMID:21237683, GO:0003995=GO_REF:0000002, GO:0070991=PMID:21237683, GO:0033539=PMID:21237683, GO:0016627=GO_REF:0000002, GO:0004466=PMID:21237683, GO:0005777=GO_REF:0000024, GO:0016772=GO_REF:0000002} Q709F0 Acyl-CoA dehydrogenase family member 11 protein 20111020 {GO:0005739=IEA, GO:0017099=IDA, GO:0031966=IDA, GO:0050660=IEA, GO:0005634=IDA, GO:0003995=IEA, GO:0070991=IDA, GO:0033539=IDA, GO:0016627=IEA, GO:0004466=IDA, GO:0005777=ISS, GO:0016772=IEA} fatty acid beta-oxidation using acyl-CoA dehydrogenase mitochondrial membrane, mitochondrion, nucleus, peroxisome acyl-CoA dehydrogenase activity, flavin adenine dinucleotide binding, long-chain-acyl-CoA dehydrogenase activity, medium-chain-acyl-CoA dehydrogenase activity, oxidoreductase activity, acting on the CH-CH group of donors, transferase activity, transferring phosphorus-containing groups, very-long-chain-acyl-CoA dehydrogenase activity Human UniProtKB:B3DMA2 ACAD8 Reactome UniProtKB {GO:0006629=PMID:10524212, GO:0034641=Reactome:REACT_13, GO:0006355=GO_REF:0000037, GO:0005759=Reactome:REACT_630, GO:0050660=GO_REF:0000002, GO:0006574=GO_REF:0000041, GO:0009083=Reactome:REACT_197, GO:0003995=Reactome:REACT_630, GO:0044281=Reactome:REACT_111217, GO:0016627=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q9UKU7 Isobutyryl-CoA dehydrogenase, mitochondrial protein 20100212 {GO:0006629=TAS, GO:0034641=TAS, GO:0006355=IEA, GO:0005759=TAS, GO:0050660=IEA, GO:0006574=IEA, GO:0009083=TAS, GO:0003995=EXP, GO:0044281=TAS, GO:0016627=IEA, GO:0006351=IEA} branched-chain amino acid catabolic process, cellular nitrogen compound metabolic process, lipid metabolic process, regulation of transcription, DNA-dependent, small molecule metabolic process, transcription, DNA-dependent, valine catabolic process mitochondrial matrix acyl-CoA dehydrogenase activity, flavin adenine dinucleotide binding, oxidoreductase activity, acting on the CH-CH group of donors Human ACAD9 LIFEdb UniProtKB {GO:0005739=GO_REF:0000054, GO:0050660=GO_REF:0000002, GO:0005634=PMID:21237683, GO:0003995=GO_REF:0000002, GO:0030425=PMID:21237683} Q9H845 Acyl-CoA dehydrogenase family member 9, mitochondrial protein 20100607 {GO:0005739=IDA, GO:0050660=IEA, GO:0005634=IDA, GO:0003995=IEA, GO:0030425=IDA} dendrite, mitochondrion, nucleus acyl-CoA dehydrogenase activity, flavin adenine dinucleotide binding Human ACADL HPA UniProtKB {GO:0090181=GO_REF:0000024, GO:0001659=GO_REF:0000024, GO:0031966=GO_REF:0000019, GO:0006635=Reactome:REACT_1473, GO:0016401=GO_REF:0000024, GO:0044242=GO_REF:0000024, GO:0050660=GO_REF:0000019, GO:0045717=GO_REF:0000024, GO:0046322=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0033539=GO_REF:0000024, GO:0019254=GO_REF:0000024, GO:0004466=GO_REF:0000024, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0051289=GO_REF:0000019, GO:0005759=Reactome:REACT_2238, GO:0042758=GO_REF:0000019, GO:0003995=Reactome:REACT_2238, GO:0000062=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0042413=GO_REF:0000024, GO:0055114=GO_REF:0000024} P28330 Long-chain specific acyl-CoA dehydrogenase, mitochondrial protein 20081203 {GO:0090181=ISS, GO:0001659=ISS, GO:0031966=IEA, GO:0006635=TAS, GO:0016401=ISS, GO:0044242=ISS, GO:0050660=IEA, GO:0045717=ISS, GO:0046322=ISS, GO:0044281=TAS, GO:0033539=ISS, GO:0019254=ISS, GO:0004466=ISS, GO:0005739=IDA, GO:0005737=IDA, GO:0051289=IEA, GO:0005759=TAS, GO:0042758=IEA, GO:0003995=TAS, GO:0000062=IEA, GO:0044255=TAS, GO:0042413=ISS, GO:0055114=ISS} carnitine catabolic process, carnitine metabolic process, CoA-linked, cellular lipid catabolic process, cellular lipid metabolic process, fatty acid beta-oxidation, fatty acid beta-oxidation using acyl-CoA dehydrogenase, long-chain fatty acid catabolic process, negative regulation of fatty acid biosynthetic process, negative regulation of fatty acid oxidation, oxidation-reduction process, protein homotetramerization, regulation of cholesterol metabolic process, small molecule metabolic process, temperature homeostasis cytoplasm, mitochondrial matrix, mitochondrial membrane, mitochondrion acyl-CoA dehydrogenase activity, fatty-acyl-CoA binding, flavin adenine dinucleotide binding, long-chain-acyl-CoA dehydrogenase activity, palmitoyl-CoA oxidase activity Human ACADM HPA UniProtKB {GO:0030424=PMID:21237683, GO:0006635=Reactome:REACT_1473, GO:0005978=GO_REF:0000019, GO:0050660=GO_REF:0000002, GO:0009409=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0009791=GO_REF:0000019, GO:0019254=PMID:16972171, GO:0033539=PMID:1902818, GO:0016627=GO_REF:0000002, GO:0042802=PMID:19224950, GO:0001889=GO_REF:0000019, GO:0005739=GO_REF:0000052, GO:0006111=GO_REF:0000019, GO:0042594=GO_REF:0000019, GO:0005759=Reactome:REACT_116020, GO:0045329=PMID:16972171, GO:0051793=PMID:1970566, GO:0003995=GO_REF:0000002, GO:0051791=PMID:1970566, GO:0070991=PMID:1970566, GO:0055007=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0055114=PMID:1902818} Q5T4U5 Acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain, isoform CRA_a protein 20080205 {GO:0030424=IDA, GO:0006635=TAS, GO:0005978=IEA, GO:0050660=IEA, GO:0009409=IEA, GO:0044281=TAS, GO:0009791=IEA, GO:0019254=IMP, GO:0033539=IDA, GO:0016627=IEA, GO:0042802=IDA, GO:0001889=IEA, GO:0005739=IDA, GO:0006111=IEA, GO:0042594=IEA, GO:0005759=TAS, GO:0045329=IMP, GO:0051793=IDA, GO:0003995=IEA, GO:0051791=IDA, GO:0070991=IDA, GO:0055007=IEA, GO:0044255=TAS, GO:0055114=IDA} cardiac muscle cell differentiation, carnitine biosynthetic process, carnitine metabolic process, CoA-linked, cellular lipid metabolic process, fatty acid beta-oxidation, fatty acid beta-oxidation using acyl-CoA dehydrogenase, glycogen biosynthetic process, liver development, medium-chain fatty acid catabolic process, medium-chain fatty acid metabolic process, oxidation-reduction process, post-embryonic development, regulation of gluconeogenesis, response to cold, response to starvation, small molecule metabolic process axon, mitochondrial matrix, mitochondrion acyl-CoA dehydrogenase activity, flavin adenine dinucleotide binding, identical protein binding, medium-chain-acyl-CoA dehydrogenase activity, oxidoreductase activity, acting on the CH-CH group of donors Human ACADS Reactome UniProtKB {GO:0031966=GO_REF:0000019, GO:0006635=Reactome:REACT_1473, GO:0050660=GO_REF:0000002, GO:0004085=GO_REF:0000003, GO:0051384=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0033539=GO_REF:0000019, GO:0005739=PMID:16729965, GO:0042594=GO_REF:0000019, GO:0051289=GO_REF:0000019, GO:0005759=Reactome:REACT_1592, GO:0003995=Reactome:REACT_1742, GO:0000062=GO_REF:0000019, GO:0046359=GO_REF:0000019, GO:0044255=Reactome:REACT_22279} P16219 Short-chain specific acyl-CoA dehydrogenase, mitochondrial protein 20130213 {GO:0031966=IEA, GO:0006635=TAS, GO:0050660=IEA, GO:0004085=IEA, GO:0051384=IEA, GO:0044281=TAS, GO:0033539=IEA, GO:0005739=IDA, GO:0042594=IEA, GO:0051289=IEA, GO:0005759=TAS, GO:0003995=TAS, GO:0000062=IEA, GO:0046359=IEA, GO:0044255=TAS} butyrate catabolic process, cellular lipid metabolic process, fatty acid beta-oxidation, fatty acid beta-oxidation using acyl-CoA dehydrogenase, protein homotetramerization, response to glucocorticoid stimulus, response to starvation, small molecule metabolic process mitochondrial matrix, mitochondrial membrane, mitochondrion acyl-CoA dehydrogenase activity, butyryl-CoA dehydrogenase activity, fatty-acyl-CoA binding, flavin adenine dinucleotide binding Human ACADSB Reactome UniProtKB {GO:0005739=PMID:7698750, GO:0034641=Reactome:REACT_13, GO:0005759=Reactome:REACT_1285, GO:0050660=GO_REF:0000002, GO:0006631=GO_REF:0000037, GO:0009083=Reactome:REACT_197, GO:0003995=Reactome:REACT_1285, GO:0044281=Reactome:REACT_111217} P45954 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial protein 20100211 {GO:0005739=TAS, GO:0034641=TAS, GO:0005759=TAS, GO:0050660=IEA, GO:0006631=IEA, GO:0009083=TAS, GO:0003995=EXP, GO:0044281=TAS} branched-chain amino acid catabolic process, cellular nitrogen compound metabolic process, fatty acid metabolic process, small molecule metabolic process mitochondrial matrix, mitochondrion acyl-CoA dehydrogenase activity, flavin adenine dinucleotide binding Human ACADVL BHF-UCL UniProtKB {GO:0042645=PMID:18063578, GO:0090181=GO_REF:0000024, GO:0001659=GO_REF:0000024, GO:0006635=Reactome:REACT_1473, GO:0050660=GO_REF:0000002, GO:0045717=GO_REF:0000024, GO:0005743=GO_REF:0000039, GO:0046322=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0033539=GO_REF:0000024, GO:0016627=GO_REF:0000002, GO:0004466=PMID:8466512, GO:0030968=Reactome:REACT_18356, GO:0005739=GO_REF:0000024, GO:0005759=Reactome:REACT_115600, GO:0003995=Reactome:REACT_398, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0015980=PMID:7479827, GO:0044255=Reactome:REACT_22279} P49748 Very long-chain specific acyl-CoA dehydrogenase, mitochondrial protein 20100304 {GO:0042645=IDA, GO:0090181=ISS, GO:0001659=ISS, GO:0006635=TAS, GO:0050660=IEA, GO:0045717=ISS, GO:0005743=IEA, GO:0046322=ISS, GO:0044281=TAS, GO:0033539=ISS, GO:0016627=IEA, GO:0004466=TAS, GO:0030968=TAS, GO:0005739=ISS, GO:0005759=TAS, GO:0003995=TAS, GO:0006987=TAS, GO:0044267=TAS, GO:0015980=TAS, GO:0044255=TAS} activation of signaling protein activity involved in unfolded protein response, cellular lipid metabolic process, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, energy derivation by oxidation of organic compounds, fatty acid beta-oxidation, fatty acid beta-oxidation using acyl-CoA dehydrogenase, negative regulation of fatty acid biosynthetic process, negative regulation of fatty acid oxidation, regulation of cholesterol metabolic process, small molecule metabolic process, temperature homeostasis mitochondrial inner membrane, mitochondrial matrix, mitochondrial nucleoid, mitochondrion acyl-CoA dehydrogenase activity, flavin adenine dinucleotide binding, long-chain-acyl-CoA dehydrogenase activity, oxidoreductase activity, acting on the CH-CH group of donors Human UniProtKB:P50544 ACAN InterPro UniProtKB {GO:0005515=PMID:17588949, GO:0005975=Reactome:REACT_474, GO:0005796=Reactome:REACT_121317, GO:0005509=GO_REF:0000002, GO:0005578=GO_REF:0000039, GO:0005576=Reactome:REACT_121303, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0042339=Reactome:REACT_121288, GO:0005604=GO_REF:0000019, GO:0030166=GO_REF:0000019, GO:0001501=PMID:1569188, GO:0005540=GO_REF:0000002, GO:0002063=GO_REF:0000019, GO:0018146=Reactome:REACT_121120, GO:0001502=GO_REF:0000019, GO:0030199=GO_REF:0000019, GO:0042340=Reactome:REACT_121313, GO:0006508=PMID:1569188, GO:0030246=GO_REF:0000002, GO:0007155=GO_REF:0000002, GO:0030203=Reactome:REACT_121315, GO:0043202=Reactome:REACT_121303, GO:0005201=PMID:1569188} Q6PID9 Aggrecan protein 20130413 {GO:0005515=IPI, GO:0005975=TAS, GO:0005796=TAS, GO:0005509=IEA, GO:0005578=IEA, GO:0005576=TAS, GO:0044281=TAS, GO:0046872=IEA, GO:0042339=TAS, GO:0005604=IEA, GO:0030166=IEA, GO:0001501=NAS, GO:0005540=IEA, GO:0002063=IEA, GO:0018146=TAS, GO:0001502=IEA, GO:0030199=IEA, GO:0042340=TAS, GO:0006508=NAS, GO:0030246=IEA, GO:0007155=IEA, GO:0030203=TAS, GO:0043202=TAS, GO:0005201=TAS} carbohydrate metabolic process, cartilage condensation, cell adhesion, chondrocyte development, collagen fibril organization, glycosaminoglycan metabolic process, keratan sulfate biosynthetic process, keratan sulfate catabolic process, keratan sulfate metabolic process, proteoglycan biosynthetic process, proteolysis, skeletal system development, small molecule metabolic process Golgi lumen, basement membrane, extracellular region, lysosomal lumen, proteinaceous extracellular matrix calcium ion binding, carbohydrate binding, extracellular matrix structural constituent, hyaluronic acid binding, metal ion binding, protein binding Human InterPro:IPR000538 ACAP1 UniProtKB UniProtKB {GO:0008060=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0032312=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0015031=GO_REF:0000037} Q15027 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 protein 20130413 {GO:0008060=IEA, GO:0005543=IEA, GO:0032312=IEA, GO:0008270=IEA, GO:0015031=IEA} protein transport, regulation of ARF GTPase activity ARF GTPase activator activity, phospholipid binding, zinc ion binding Human UniProtKB-KW:KW-0653 ACAP2 InterPro UniProtKB {GO:0008060=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0032312=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q15057 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 protein 20130413 {GO:0008060=IEA, GO:0005543=IEA, GO:0032312=IEA, GO:0008270=IEA} regulation of ARF GTPase activity ARF GTPase activator activity, phospholipid binding, zinc ion binding Human InterPro:IPR001164 ACAP3 InterPro UniProtKB {GO:0008060=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0032312=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q96P50 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 protein 20130413 {GO:0008060=IEA, GO:0005543=IEA, GO:0032312=IEA, GO:0008270=IEA} regulation of ARF GTPase activity ARF GTPase activator activity, phospholipid binding, zinc ion binding Human InterPro:IPR001164 ACAT1 HPA UniProtKB {GO:0014070=GO_REF:0000019, GO:0050662=GO_REF:0000019, GO:0016747=GO_REF:0000002, GO:0072229=GO_REF:0000019, GO:0005743=GO_REF:0000019, GO:0009083=Reactome:REACT_197, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0042803=GO_REF:0000019, GO:0005739=GO_REF:0000052, GO:0001889=GO_REF:0000019, GO:0034641=Reactome:REACT_13, GO:0042594=GO_REF:0000019, GO:0046952=Reactome:REACT_59, GO:0007420=GO_REF:0000019, GO:0046951=Reactome:REACT_1464, GO:0005759=Reactome:REACT_1478, GO:0046950=Reactome:REACT_1861, GO:0003985=Reactome:REACT_1478, GO:0051260=GO_REF:0000019, GO:0009725=GO_REF:0000019, GO:0019899=GO_REF:0000019, GO:0060612=GO_REF:0000019, GO:0044255=Reactome:REACT_22279} P24752 Acetyl-CoA acetyltransferase, mitochondrial protein 20080818 {GO:0014070=IEA, GO:0050662=IEA, GO:0016747=IEA, GO:0072229=IEA, GO:0005743=IEA, GO:0009083=TAS, GO:0044281=TAS, GO:0046872=IEA, GO:0042803=IEA, GO:0005739=IDA, GO:0001889=IEA, GO:0034641=TAS, GO:0042594=IEA, GO:0046952=TAS, GO:0007420=IEA, GO:0046951=TAS, GO:0005759=TAS, GO:0046950=TAS, GO:0003985=EXP, GO:0051260=IEA, GO:0009725=IEA, GO:0019899=IEA, GO:0060612=IEA, GO:0044255=TAS} adipose tissue development, brain development, branched-chain amino acid catabolic process, cellular ketone body metabolic process, cellular lipid metabolic process, cellular nitrogen compound metabolic process, ketone body biosynthetic process, ketone body catabolic process, liver development, metanephric proximal convoluted tubule development, protein homooligomerization, response to hormone stimulus, response to organic cyclic compound, response to starvation, small molecule metabolic process mitochondrial inner membrane, mitochondrial matrix, mitochondrion acetyl-CoA C-acetyltransferase activity, coenzyme binding, enzyme binding, metal ion binding, protein homodimerization activity, transferase activity, transferring acyl groups other than amino-acyl groups Human ACAT2 HPA UniProtKB {GO:0006629=PMID:7911016, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0016747=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0003985=PMID:7911016, GO:0005634=GO_REF:0000052} Q9BWD1 Acetyl-CoA acetyltransferase, cytosolic protein 20101115 {GO:0006629=IC, GO:0005739=IDA, GO:0005737=IDA, GO:0016747=IEA, GO:0005730=IDA, GO:0003985=IDA, GO:0005634=IDA} lipid metabolic process cytoplasm, mitochondrion, nucleolus, nucleus acetyl-CoA C-acetyltransferase activity, transferase activity, transferring acyl groups other than amino-acyl groups Human ACBD3 HPA UniProtKB {GO:0005739=GO_REF:0000039, GO:0006694=GO_REF:0000037, GO:0005794=GO_REF:0000052, GO:0000139=GO_REF:0000039, GO:0006810=GO_REF:0000002, GO:0016021=GO_REF:0000002, GO:0000062=GO_REF:0000002} Q9H3P7 Golgi resident protein GCP60 protein 20090616 {GO:0005739=IEA, GO:0006694=IEA, GO:0005794=IDA, GO:0000139=IEA, GO:0006810=IEA, GO:0016021=IEA, GO:0000062=IEA} steroid biosynthetic process, transport Golgi apparatus, Golgi membrane, integral to membrane, mitochondrion fatty-acyl-CoA binding Human ACBD4 UniProtKB UniProtKB {GO:0000062=GO_REF:0000002, GO:0008289=GO_REF:0000037} Q8NC06 Acyl-CoA-binding domain-containing protein 4 protein 20130413 {GO:0000062=IEA, GO:0008289=IEA} fatty-acyl-CoA binding, lipid binding Human UniProtKB-KW:KW-0446 ACBD5 InterPro UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0006810=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0000062=GO_REF:0000002, GO:0005778=GO_REF:0000039, GO:0008289=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q5T8E0 Acyl-CoA-binding domain-containing protein 5 protein 20130413 {GO:0003674=ND, GO:0008150=ND, GO:0006810=IEA, GO:0016021=IEA, GO:0000062=IEA, GO:0005778=IEA, GO:0008289=IEA, GO:0043231=IDA} biological_process, transport integral to membrane, intracellular membrane-bounded organelle, peroxisomal membrane fatty-acyl-CoA binding, lipid binding, molecular_function Human InterPro:IPR000582 ACBD6 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000062=GO_REF:0000002, GO:0008289=GO_REF:0000037} Q9BR61 Acyl-CoA-binding domain-containing protein 6 protein 20101115 {GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0000062=IEA, GO:0008289=IEA} cytoplasm, nucleolus, nucleus fatty-acyl-CoA binding, lipid binding Human ACCS UniProtKB UniProtKB {GO:0016847=PMID:11470512, GO:0030170=PMID:11470512, GO:0042803=PMID:11470512} Q96QU6 1-aminocyclopropane-1-carboxylate synthase-like protein 1 protein 20080109 {GO:0016847=IDA, GO:0030170=NAS, GO:0042803=NAS} 1-aminocyclopropane-1-carboxylate synthase activity, protein homodimerization activity, pyridoxal phosphate binding Human ACD BHF-UCL UniProtKB {GO:0005515=PMID:15380063, GO:0000781=PMID:15380063, GO:0016233=PMID:17237767, GO:0070182=PMID:17237767, GO:0001655=GO_REF:0000019, GO:0030326=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0006886=PMID:15181449, GO:0031848=PMID:18185984, GO:0051973=PMID:17237768, GO:0032211=PMID:15380063, GO:0001501=GO_REF:0000019, GO:0060381=PMID:17237767, GO:0035282=GO_REF:0000019, GO:0000723=Reactome:REACT_7970, GO:0005654=Reactome:REACT_8031, GO:0070198=PMID:15181449, GO:0032202=PMID:16880378, GO:0000783=PMID:16880378} Q96AP0 Adrenocortical dysplasia protein homolog protein 20081205 {GO:0005515=IPI, GO:0000781=IDA, GO:0016233=NAS, GO:0070182=IPI, GO:0001655=IEA, GO:0030326=IEA, GO:0003677=IEA, GO:0006886=IMP, GO:0031848=ISS, GO:0051973=IDA, GO:0032211=IMP, GO:0001501=IEA, GO:0060381=IDA, GO:0035282=IEA, GO:0000723=TAS, GO:0005654=TAS, GO:0070198=IMP, GO:0032202=IMP, GO:0000783=IDA} embryonic limb morphogenesis, intracellular protein transport, negative regulation of telomere maintenance via telomerase, positive regulation of single-stranded telomeric DNA binding, positive regulation of telomerase activity, protection from non-homologous end joining at telomere, protein localization to chromosome, telomeric region, segmentation, skeletal system development, telomere assembly, telomere capping, telomere maintenance, urogenital system development chromosome, telomeric region, nuclear telomere cap complex, nucleoplasm DNA binding, DNA polymerase binding, protein binding Human ACE BHF-UCL UniProtKB {GO:0031404=PMID:12540854, GO:0005886=PMID:17077303, GO:0002003=Reactome:REACT_147707, GO:0014910=GO_REF:0000024, GO:0005615=PMID:4322742, GO:0019229=PMID:1668266, GO:0042312=PMID:4322742, GO:0003081=PMID:1668266, GO:0002019=PMID:1668266, GO:0008144=PMID:1320019, GO:0008241=PMID:11303049, GO:0004180=GO_REF:0000037, GO:0006508=GO_REF:0000037, GO:0043171=PMID:4322742, GO:0050482=PMID:17077303, GO:0031711=PMID:17077303, GO:0001822=PMID:16116425, GO:0005576=Reactome:REACT_147705, GO:0060218=PMID:7876104, GO:0016020=GO_REF:0000002, GO:0001974=PMID:1668266, GO:0042447=PMID:7876104, GO:0008217=PMID:11303049, GO:0002005=PMID:1668266, GO:0008270=PMID:12540854, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0009897=PMID:9449382, GO:0032943=PMID:7876104, GO:0008237=GO_REF:0000024, GO:0005768=PMID:17077303} P12821 Angiotensin-converting enzyme protein 20080903 {GO:0031404=IDA, GO:0005886=IDA, GO:0002003=TAS, GO:0014910=ISS, GO:0005615=IDA, GO:0019229=IC, GO:0042312=IC, GO:0003081=IC, GO:0002019=IC, GO:0008144=IDA, GO:0008241=ISS, GO:0004180=IEA, GO:0006508=IEA, GO:0043171=IDA, GO:0050482=IDA, GO:0031711=IPI, GO:0001822=IMP, GO:0005576=TAS, GO:0060218=IC, GO:0016020=IEA, GO:0001974=IC, GO:0042447=IDA, GO:0008217=ISS, GO:0002005=IC, GO:0008270=IDA, GO:0016021=IEA, GO:0044267=TAS, GO:0009897=IDA, GO:0032943=IC, GO:0008237=ISS, GO:0005768=IDA} angiotensin catabolic process in blood, angiotensin maturation, arachidonic acid secretion, blood vessel remodeling, cellular protein metabolic process, hematopoietic stem cell differentiation, hormone catabolic process, kidney development, mononuclear cell proliferation, peptide catabolic process, proteolysis, regulation of blood pressure, regulation of renal output by angiotensin, regulation of smooth muscle cell migration, regulation of systemic arterial blood pressure by renin-angiotensin, regulation of vasoconstriction, regulation of vasodilation endosome, external side of plasma membrane, extracellular region, extracellular space, integral to membrane, membrane, plasma membrane bradykinin receptor binding, carboxypeptidase activity, chloride ion binding, drug binding, metallopeptidase activity, peptidyl-dipeptidase activity, zinc ion binding Human ACE2 GOC UniProtKB {GO:0005886=Reactome:REACT_147889, GO:0002003=Reactome:REACT_147707, GO:0046718=PMID:15165741, GO:0001817=PMID:15380922, GO:0005615=PMID:18258853, GO:0019229=PMID:15380922, GO:0003081=PMID:18258853, GO:0042312=PMID:15380922, GO:0001948=PMID:18343844, GO:0001618=PMID:18343844, GO:0042127=PMID:17703127, GO:0006508=GO_REF:0000019, GO:0008241=PMID:10924499, GO:0004180=PMID:18258853, GO:0009986=PMID:18343844, GO:0050727=PMID:15380922, GO:0005576=PMID:10969042, GO:0009615=PMID:18343844, GO:0002005=PMID:10924499, GO:0032800=PMID:18258853, GO:0008270=PMID:10924499, GO:0045121=PMID:18279660, GO:0016021=GO_REF:0000037, GO:0017046=GO_REF:0000019, GO:2000379=PMID:15380922, GO:0046813=PMID:18343844, GO:0044267=Reactome:REACT_17015, GO:0003051=PMID:18258853, GO:0008237=PMID:10924499} Q9BYF1 Angiotensin-converting enzyme 2 protein 20130413 {GO:0005886=TAS, GO:0002003=TAS, GO:0046718=TAS, GO:0001817=IC, GO:0005615=IDA, GO:0019229=IC, GO:0003081=IMP, GO:0042312=IC, GO:0001948=IPI, GO:0001618=IDA, GO:0042127=TAS, GO:0006508=IEA, GO:0008241=IDA, GO:0004180=IDA, GO:0009986=IDA, GO:0050727=IC, GO:0005576=IDA, GO:0009615=IDA, GO:0002005=IC, GO:0032800=IMP, GO:0008270=TAS, GO:0045121=TAS, GO:0016021=IEA, GO:0017046=IEA, GO:2000379=IC, GO:0046813=IDA, GO:0044267=TAS, GO:0003051=IMP, GO:0008237=IDA} angiotensin catabolic process in blood, angiotensin maturation, angiotensin-mediated drinking behavior, cellular protein metabolic process, positive regulation of reactive oxygen species metabolic process, proteolysis, receptor biosynthetic process, regulation of cell proliferation, regulation of cytokine production, regulation of inflammatory response, regulation of systemic arterial blood pressure by renin-angiotensin, regulation of vasoconstriction, regulation of vasodilation, response to virus, viral entry into host cell, virion attachment, binding of host cell surface receptor cell surface, extracellular region, extracellular space, integral to membrane, membrane raft, plasma membrane carboxypeptidase activity, glycoprotein binding, metallopeptidase activity, peptide hormone binding, peptidyl-dipeptidase activity, viral receptor activity, zinc ion binding Human ACER3 Reactome UniProtKB {GO:0070774=PMID:20068046, GO:0006665=Reactome:REACT_19323, GO:0008284=PMID:20068046, GO:0016811=GO_REF:0000002, GO:0006672=GO_REF:0000002, GO:0030148=Reactome:REACT_115810, GO:0071602=PMID:20068046, GO:0030176=PMID:11356846, GO:0044281=Reactome:REACT_111217, GO:0030173=PMID:11356846, GO:0005789=Reactome:REACT_19134, GO:0016021=GO_REF:0000002, GO:0046512=PMID:20068046} Q9NUN7 Alkaline ceramidase 3 protein 20130301 {GO:0070774=IDA, GO:0006665=TAS, GO:0008284=IMP, GO:0016811=IEA, GO:0006672=IEA, GO:0030148=TAS, GO:0071602=IDA, GO:0030176=IDA, GO:0044281=TAS, GO:0030173=IDA, GO:0005789=TAS, GO:0016021=IEA, GO:0046512=IDA} ceramide metabolic process, phytosphingosine biosynthetic process, positive regulation of cell proliferation, small molecule metabolic process, sphingolipid biosynthetic process, sphingolipid metabolic process, sphingosine biosynthetic process endoplasmic reticulum membrane, integral to Golgi membrane, integral to endoplasmic reticulum membrane, integral to membrane hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides, phytoceramidase activity Human ACHE BHF-UCL UniProtKB {GO:0004091=GO_REF:0000033, GO:0005515=PMID:18194455, GO:0003990=PMID:1517212, GO:0030054=GO_REF:0000037, GO:0031594=GO_REF:0000033, GO:0060041=GO_REF:0000019, GO:0005518=PMID:12524166, GO:0045202=PMID:8460160, GO:0031225=GO_REF:0000037, GO:0043621=GO_REF:0000019, GO:0005615=GO_REF:0000033, GO:0042803=PMID:12524166, GO:0031623=GO_REF:0000019, GO:0045211=GO_REF:0000033, GO:0042166=PMID:8349597, GO:0006656=Reactome:REACT_121238, GO:0005794=PMID:15454088, GO:0009986=GO_REF:0000033, GO:0005605=PMID:16289501, GO:0045212=GO_REF:0000019, GO:0007416=PMID:11283752, GO:0007271=GO_REF:0000033, GO:0042734=GO_REF:0000033, GO:0007517=PMID:11283752, GO:0032223=PMID:1517212, GO:0002076=PMID:15454088, GO:0043236=PMID:12524166, GO:0001507=PMID:1517212, GO:0005788=GO_REF:0000033, GO:0006581=PMID:1517212, GO:0006644=Reactome:REACT_120870, GO:0050770=GO_REF:0000033, GO:0030424=GO_REF:0000033, GO:0048471=PMID:14766237, GO:0005886=Reactome:REACT_14816, GO:0008283=PMID:11283752, GO:0004104=PMID:1517212, GO:0050714=PMID:11283752, GO:0007268=Reactome:REACT_13685, GO:0005634=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0019695=GO_REF:0000033, GO:0030425=GO_REF:0000033, GO:0001540=PMID:11283752, GO:0017171=PMID:3954986, GO:0007155=PMID:15454088, GO:0051262=GO_REF:0000019, GO:0009611=PMID:11283752, GO:0005576=PMID:1517212, GO:0042982=PMID:12769797, GO:0007399=PMID:11283752, GO:0048814=GO_REF:0000033, GO:0006260=PMID:11283752, GO:0001919=GO_REF:0000019, GO:0016020=PMID:16262697, GO:0016787=PMID:1517212, GO:0042136=Reactome:REACT_13583, GO:0046474=Reactome:REACT_121401} P22303 Acetylcholinesterase protein 20120102 {GO:0004091=IBA, GO:0005515=IPI, GO:0003990=IDA, GO:0030054=IEA, GO:0031594=IBA, GO:0060041=IEA, GO:0005518=IDA, GO:0045202=IDA, GO:0031225=IEA, GO:0043621=IEA, GO:0005615=IBA, GO:0042803=IPI, GO:0031623=IEA, GO:0045211=IBA, GO:0042166=IDA, GO:0006656=TAS, GO:0005794=IDA, GO:0009986=IBA, GO:0005605=NAS, GO:0045212=IEA, GO:0007416=TAS, GO:0007271=IBA, GO:0042734=IBA, GO:0007517=TAS, GO:0032223=IC, GO:0002076=IEP, GO:0043236=IDA, GO:0001507=NAS, GO:0005788=IBA, GO:0006581=IDA, GO:0006644=TAS, GO:0050770=IBA, GO:0030424=IBA, GO:0048471=IDA, GO:0005886=TAS, GO:0008283=TAS, GO:0004104=IDA, GO:0050714=TAS, GO:0007268=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0019695=IBA, GO:0030425=IBA, GO:0001540=TAS, GO:0017171=IDA, GO:0007155=IDA, GO:0051262=IEA, GO:0009611=TAS, GO:0005576=IDA, GO:0042982=TAS, GO:0007399=TAS, GO:0048814=IBA, GO:0006260=TAS, GO:0001919=IEA, GO:0016020=IDA, GO:0016787=IDA, GO:0042136=TAS, GO:0046474=TAS} DNA replication, acetylcholine catabolic process, acetylcholine catabolic process in synaptic cleft, amyloid precursor protein metabolic process, cell adhesion, cell proliferation, choline metabolic process, glycerophospholipid biosynthetic process, muscle organ development, negative regulation of synaptic transmission, cholinergic, nervous system development, neurotransmitter biosynthetic process, neurotransmitter receptor biosynthetic process, osteoblast development, phosphatidylcholine biosynthetic process, phospholipid metabolic process, positive regulation of protein secretion, protein tetramerization, receptor internalization, regulation of axonogenesis, regulation of dendrite morphogenesis, regulation of receptor recycling, response to wounding, retina development in camera-type eye, small molecule metabolic process, synapse assembly, synaptic transmission, synaptic transmission, cholinergic Golgi apparatus, anchored to membrane, axon, basal lamina, cell junction, cell surface, dendrite, endoplasmic reticulum lumen, extracellular region, extracellular space, membrane, neuromuscular junction, nucleus, perinuclear region of cytoplasm, plasma membrane, postsynaptic membrane, presynaptic membrane, synapse acetylcholine binding, acetylcholinesterase activity, beta-amyloid binding, carboxylesterase activity, cholinesterase activity, collagen binding, hydrolase activity, laminin binding, protein binding, protein homodimerization activity, protein self-association, serine hydrolase activity Human ACIN1 GOC UniProtKB {GO:0005515=PMID:20195357, GO:0006200=PMID:10490026, GO:0005730=GO_REF:0000052, GO:0006915=Reactome:REACT_578, GO:0005634=GO_REF:0000052, GO:0003676=PMID:10490026, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_12450, GO:0005737=GO_REF:0000052, GO:0000166=GO_REF:0000002, GO:0016607=GO_REF:0000039, GO:0045657=PMID:12393560, GO:0030218=PMID:11208865, GO:0030263=PMID:10490026, GO:0019899=PMID:10490026, GO:0016887=PMID:10490026} Q9UKV3 Apoptotic chromatin condensation inducer in the nucleus protein 20130413 {GO:0005515=IPI, GO:0006200=NAS, GO:0005730=IDA, GO:0006915=TAS, GO:0005634=IDA, GO:0003676=NAS, GO:0006921=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0000166=IEA, GO:0016607=IEA, GO:0045657=IEP, GO:0030218=IEP, GO:0030263=IDA, GO:0019899=NAS, GO:0016887=NAS} ATP catabolic process, apoptotic chromosome condensation, apoptotic process, cellular component disassembly involved in execution phase of apoptosis, erythrocyte differentiation, positive regulation of monocyte differentiation cytoplasm, cytosol, nuclear speck, nucleolus, nucleus ATPase activity, enzyme binding, nucleic acid binding, nucleotide binding, protein binding Human ACLY HPA UniProtKB {GO:0048037=GO_REF:0000002, GO:0044262=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0006200=PMID:1371749, GO:0003878=Reactome:REACT_1141, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0035338=Reactome:REACT_1319, GO:0015936=PMID:1371749, GO:0005524=GO_REF:0000037, GO:0009346=PMID:1371749, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_1577, GO:0005739=GO_REF:0000019, GO:0006101=PMID:1371749, GO:0005737=GO_REF:0000052, GO:0031325=Reactome:REACT_2122, GO:0006112=Reactome:REACT_1505, GO:0019432=Reactome:REACT_1190, GO:0004775=GO_REF:0000002, GO:0044255=Reactome:REACT_22279} P53396 ATP-citrate synthase protein 20111111 {GO:0048037=IEA, GO:0044262=IEA, GO:0005886=IDA, GO:0006200=TAS, GO:0003878=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0035338=TAS, GO:0015936=TAS, GO:0005524=IEA, GO:0009346=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0006101=TAS, GO:0005737=IDA, GO:0031325=TAS, GO:0006112=TAS, GO:0019432=TAS, GO:0004775=IEA, GO:0044255=TAS} ATP catabolic process, cellular carbohydrate metabolic process, cellular lipid metabolic process, citrate metabolic process, coenzyme A metabolic process, energy reserve metabolic process, long-chain fatty-acyl-CoA biosynthetic process, positive regulation of cellular metabolic process, small molecule metabolic process, triglyceride biosynthetic process citrate lyase complex, cytoplasm, cytosol, mitochondrion, nucleolus, nucleus, plasma membrane ATP binding, ATP citrate synthase activity, cofactor binding, metal ion binding, succinate-CoA ligase (ADP-forming) activity Human ACMSD Reactome UniProtKB {GO:0034641=Reactome:REACT_13, GO:0006569=Reactome:REACT_916, GO:0046874=PMID:12140278, GO:0044281=Reactome:REACT_111217, GO:0001760=PMID:12140278, GO:0046872=GO_REF:0000037, GO:0005829=PMID:12140278} Q8TDX5 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase protein 20130213 {GO:0034641=TAS, GO:0006569=TAS, GO:0046874=IDA, GO:0044281=TAS, GO:0001760=IDA, GO:0046872=IEA, GO:0005829=IDA} cellular nitrogen compound metabolic process, quinolinate metabolic process, small molecule metabolic process, tryptophan catabolic process cytosol aminocarboxymuconate-semialdehyde decarboxylase activity, metal ion binding Human ACO1 InterPro UniProtKB {GO:0005515=PMID:19762596, GO:0005794=PMID:16144863, GO:0051539=PMID:16407072, GO:0006099=GO_REF:0000037, GO:0005783=PMID:16144863, GO:0003994=PMID:8041788, GO:0003723=PMID:1946430, GO:0010040=PMID:8041788, GO:0009791=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0006417=GO_REF:0000019, GO:0005829=PMID:16527810, GO:0005739=GO_REF:0000052, GO:0006879=GO_REF:0000019, GO:0006101=PMID:16527810, GO:0050892=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0052633=GO_REF:0000003, GO:0008152=GO_REF:0000002, GO:0052632=GO_REF:0000003, GO:0030350=PMID:8041788} Q5VZA6 Cytoplasmic aconitate hydratase protein 20130413 {GO:0005515=IPI, GO:0005794=IDA, GO:0051539=IDA, GO:0006099=IEA, GO:0005783=IDA, GO:0003994=IDA, GO:0003723=IDA, GO:0010040=IDA, GO:0009791=IEA, GO:0046872=IEA, GO:0006417=IEA, GO:0005829=IDA, GO:0005739=IDA, GO:0006879=IEA, GO:0006101=IDA, GO:0050892=IEA, GO:0005737=IDA, GO:0052633=IEA, GO:0008152=IEA, GO:0052632=IEA, GO:0030350=IDA} cellular iron ion homeostasis, citrate metabolic process, intestinal absorption, metabolic process, post-embryonic development, regulation of translation, response to iron(II) ion, tricarboxylic acid cycle Golgi apparatus, cytoplasm, cytosol, endoplasmic reticulum, mitochondrion 4 iron, 4 sulfur cluster binding, RNA binding, aconitate hydratase activity, citrate hydro-lyase (cis-aconitate-forming) activity, iron-responsive element binding, isocitrate hydro-lyase (cis-aconitate-forming) activity, metal ion binding, protein binding Human InterPro:IPR001030|InterPro:IPR015931|InterPro:IPR015932|InterPro:IPR015934|InterPro:IPR015937 ACO2 HPA UniProtKB {GO:0008219=GO_REF:0000037, GO:0051538=GO_REF:0000019, GO:0006099=Reactome:REACT_1785, GO:0051539=GO_REF:0000019, GO:0005506=PMID:9630632, GO:0003994=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0006091=PMID:9630632, GO:0005739=GO_REF:0000052, GO:0006102=GO_REF:0000019, GO:0006101=PMID:9630632, GO:0005759=Reactome:REACT_21262, GO:0052633=GO_REF:0000003, GO:0052632=GO_REF:0000003} Q99798 Aconitate hydratase, mitochondrial protein 20101115 {GO:0008219=IEA, GO:0051538=IEA, GO:0006099=TAS, GO:0051539=IEA, GO:0005506=IDA, GO:0003994=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0006091=TAS, GO:0005739=IDA, GO:0006102=IEA, GO:0006101=IDA, GO:0005759=TAS, GO:0052633=IEA, GO:0052632=IEA} cell death, citrate metabolic process, generation of precursor metabolites and energy, isocitrate metabolic process, small molecule metabolic process, tricarboxylic acid cycle mitochondrial matrix, mitochondrion, nucleus 3 iron, 4 sulfur cluster binding, 4 iron, 4 sulfur cluster binding, aconitate hydratase activity, citrate hydro-lyase (cis-aconitate-forming) activity, iron ion binding, isocitrate hydro-lyase (cis-aconitate-forming) activity Human ACOT1 HPA UniProtKB {GO:0047617=PMID:16940157, GO:0004091=GO_REF:0000037, GO:0005739=GO_REF:0000052, GO:0000038=PMID:16940157, GO:0006637=PMID:16940157, GO:0001676=PMID:16940157, GO:0016290=GO_REF:0000003, GO:0016790=GO_REF:0000002, GO:0005829=PMID:16940157} Q86TX2 Acyl-coenzyme A thioesterase 1 protein 20111111 {GO:0047617=IDA, GO:0004091=IEA, GO:0005739=IDA, GO:0000038=IDA, GO:0006637=IDA, GO:0001676=IDA, GO:0016290=IEA, GO:0016790=IEA, GO:0005829=IDA} acyl-CoA metabolic process, long-chain fatty acid metabolic process, very long-chain fatty acid metabolic process cytosol, mitochondrion acyl-CoA hydrolase activity, carboxylesterase activity, palmitoyl-CoA hydrolase activity, thiolester hydrolase activity Human ACOT13 UniProtKB UniProtKB {GO:0047617=PMID:16934754, GO:0005739=GO_REF:0000039, GO:0051289=PMID:16934754} Q9NPJ3 Acyl-coenzyme A thioesterase 13 protein 20090521 {GO:0047617=IDA, GO:0005739=IEA, GO:0051289=IPI} protein homotetramerization mitochondrion acyl-CoA hydrolase activity Human ACOT2 HPA UniProtKB {GO:0047617=PMID:16940157, GO:0004091=GO_REF:0000037, GO:0005739=GO_REF:0000052, GO:0000038=PMID:16940157, GO:0006637=PMID:16940157, GO:0001676=PMID:16940157, GO:0016290=GO_REF:0000003, GO:0005102=PMID:20178365} P49753 Acyl-coenzyme A thioesterase 2, mitochondrial protein 20111111 {GO:0047617=IDA, GO:0004091=IEA, GO:0005739=IDA, GO:0000038=IDA, GO:0006637=IDA, GO:0001676=IDA, GO:0016290=IEA, GO:0005102=IPI} acyl-CoA metabolic process, long-chain fatty acid metabolic process, very long-chain fatty acid metabolic process mitochondrion acyl-CoA hydrolase activity, carboxylesterase activity, palmitoyl-CoA hydrolase activity, receptor binding Human ACOT4 HGNC UniProtKB {GO:0004091=GO_REF:0000037, GO:0004778=PMID:16141203, GO:0000038=PMID:16940157, GO:0006637=PMID:16940157, GO:0001676=PMID:16940157, GO:0046459=PMID:16940157, GO:0043648=PMID:16940157, GO:0016290=GO_REF:0000003, GO:0043649=PMID:16141203, GO:0005102=PMID:20178365, GO:0047617=PMID:16940157, GO:0032789=PMID:16940157, GO:0032788=PMID:16940157, GO:0006104=PMID:16940157, GO:0019605=PMID:16940157, GO:0005777=PMID:16940157} Q8N9L9 Acyl-coenzyme A thioesterase 4 protein 20061213 {GO:0004091=IEA, GO:0004778=IDA, GO:0000038=IDA, GO:0006637=IDA, GO:0001676=IDA, GO:0046459=IDA, GO:0043648=IDA, GO:0016290=IEA, GO:0043649=IDA, GO:0005102=IPI, GO:0047617=IDA, GO:0032789=IDA, GO:0032788=IDA, GO:0006104=IDA, GO:0019605=IDA, GO:0005777=IDA} acyl-CoA metabolic process, butyrate metabolic process, dicarboxylic acid catabolic process, dicarboxylic acid metabolic process, long-chain fatty acid metabolic process, saturated monocarboxylic acid metabolic process, short-chain fatty acid metabolic process, succinyl-CoA metabolic process, unsaturated monocarboxylic acid metabolic process, very long-chain fatty acid metabolic process peroxisome acyl-CoA hydrolase activity, carboxylesterase activity, palmitoyl-CoA hydrolase activity, receptor binding, succinyl-CoA hydrolase activity Human ACOT7 PINC UniProtKB {GO:0006629=PMID:10578051, GO:0005739=GO_REF:0000039, GO:0004091=GO_REF:0000037, GO:0043005=GO_REF:0000019, GO:0005737=PMID:10578051, GO:0016290=GO_REF:0000003, GO:0003824=PMID:10578051, GO:0000062=PMID:10578051, GO:0044297=GO_REF:0000019, GO:0009062=GO_REF:0000019, GO:0005829=GO_REF:0000019} O00154 Cytosolic acyl coenzyme A thioester hydrolase protein 20030904 {GO:0006629=TAS, GO:0005739=IEA, GO:0004091=IEA, GO:0043005=IEA, GO:0005737=TAS, GO:0016290=IEA, GO:0003824=TAS, GO:0000062=TAS, GO:0044297=IEA, GO:0009062=IEA, GO:0005829=IEA} fatty acid catabolic process, lipid metabolic process cell body, cytoplasm, cytosol, mitochondrion, neuron projection carboxylesterase activity, catalytic activity, fatty-acyl-CoA binding, palmitoyl-CoA hydrolase activity Human ACOT8 InterPro UniProtKB {GO:0004091=GO_REF:0000037, GO:0005515=PMID:22190034, GO:0052815=PMID:9299485, GO:0006637=GO_REF:0000002, GO:0005782=Reactome:REACT_120988, GO:0006699=Reactome:REACT_11054, GO:0043649=PMID:16141203, GO:0016290=PMID:9299485, GO:0005102=PMID:20178365, GO:0044281=Reactome:REACT_111217, GO:0036109=Reactome:REACT_121147, GO:0033559=Reactome:REACT_121284, GO:0047617=GO_REF:0000002, GO:0005739=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0008206=Reactome:REACT_11040, GO:0033540=Reactome:REACT_17062, GO:0044255=Reactome:REACT_16957, GO:0033882=GO_REF:0000003} Q9BR14 Acyl-coenzyme A thioesterase 8 protein 20130413 {GO:0004091=IEA, GO:0005515=IPI, GO:0052815=IDA, GO:0006637=IEA, GO:0005782=TAS, GO:0006699=TAS, GO:0043649=IDA, GO:0016290=IDA, GO:0005102=IPI, GO:0044281=TAS, GO:0036109=TAS, GO:0033559=TAS, GO:0047617=IEA, GO:0005739=IEA, GO:0019048=IEA, GO:0008206=TAS, GO:0033540=TAS, GO:0044255=TAS, GO:0033882=IEA} acyl-CoA metabolic process, alpha-linolenic acid metabolic process, bile acid biosynthetic process, bile acid metabolic process, cellular lipid metabolic process, dicarboxylic acid catabolic process, fatty acid beta-oxidation using acyl-CoA oxidase, small molecule metabolic process, unsaturated fatty acid metabolic process, virus-host interaction mitochondrion, peroxisomal matrix acyl-CoA hydrolase activity, carboxylesterase activity, choloyl-CoA hydrolase activity, medium-chain acyl-CoA hydrolase activity, palmitoyl-CoA hydrolase activity, protein binding, receptor binding Human InterPro:IPR003703 ACOT9 HGNC UniProtKB {GO:0005739=GO_REF:0000024, GO:0004091=GO_REF:0000037, GO:0006637=GO_REF:0000024, GO:0003986=GO_REF:0000024} Q9Y305 Acyl-coenzyme A thioesterase 9, mitochondrial protein 20050921 {GO:0005739=ISS, GO:0004091=IEA, GO:0006637=ISS, GO:0003986=ISS} acyl-CoA metabolic process mitochondrion acetyl-CoA hydrolase activity, carboxylesterase activity Human UniProtKB:Q9R0X4 ACOX1 BHF-UCL UniProtKB {GO:0006629=PMID:8117268, GO:0000038=PMID:18536048, GO:0019395=PMID:7876265, GO:0005504=GO_REF:0000019, GO:0006693=PMID:7876265, GO:0006635=GO_REF:0000002, GO:0016401=GO_REF:0000019, GO:0005782=Reactome:REACT_120938, GO:0050660=GO_REF:0000002, GO:0005102=PMID:20178365, GO:0006091=PMID:7876265, GO:0007283=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0036109=Reactome:REACT_121147, GO:0033559=Reactome:REACT_121284, GO:0005739=GO_REF:0000019, GO:0047485=PMID:18281296, GO:0003997=PMID:18536048, GO:0006631=GO_REF:0000002, GO:0003995=GO_REF:0000002, GO:0033540=PMID:18536048, GO:0044255=Reactome:REACT_22279, GO:0005778=GO_REF:0000019, GO:0005777=PMID:8117268} Q15067 Peroxisomal acyl-coenzyme A oxidase 1 protein 20091126 {GO:0006629=IDA, GO:0000038=IMP, GO:0019395=IMP, GO:0005504=IEA, GO:0006693=IMP, GO:0006635=IEA, GO:0016401=IEA, GO:0005782=TAS, GO:0050660=IEA, GO:0005102=IPI, GO:0006091=IMP, GO:0007283=IEA, GO:0044281=TAS, GO:0036109=TAS, GO:0033559=TAS, GO:0005739=IEA, GO:0047485=IPI, GO:0003997=IMP, GO:0006631=IEA, GO:0003995=IEA, GO:0033540=IMP, GO:0044255=TAS, GO:0005778=IEA, GO:0005777=IDA} alpha-linolenic acid metabolic process, cellular lipid metabolic process, fatty acid beta-oxidation, fatty acid beta-oxidation using acyl-CoA oxidase, fatty acid metabolic process, fatty acid oxidation, generation of precursor metabolites and energy, lipid metabolic process, prostaglandin metabolic process, small molecule metabolic process, spermatogenesis, unsaturated fatty acid metabolic process, very long-chain fatty acid metabolic process mitochondrion, peroxisomal matrix, peroxisomal membrane, peroxisome acyl-CoA dehydrogenase activity, acyl-CoA oxidase activity, fatty acid binding, flavin adenine dinucleotide binding, palmitoyl-CoA oxidase activity, protein N-terminus binding, receptor binding Human ACOX2 Reactome UniProtKB {GO:0016402=Reactome:REACT_17014, GO:0006635=GO_REF:0000002, GO:0005782=Reactome:REACT_17014, GO:0006699=Reactome:REACT_11054, GO:0033791=GO_REF:0000003, GO:0050660=GO_REF:0000002, GO:0005102=PMID:20178365, GO:0044281=Reactome:REACT_111217, GO:0003997=Reactome:REACT_10074, GO:0006631=GO_REF:0000002, GO:0003995=GO_REF:0000002, GO:0008206=Reactome:REACT_11040, GO:0033540=Reactome:REACT_17017, GO:0044255=Reactome:REACT_16957, GO:0005777=GO_REF:0000002} Q99424 Peroxisomal acyl-coenzyme A oxidase 2 protein 20130213 {GO:0016402=TAS, GO:0006635=IEA, GO:0005782=TAS, GO:0006699=TAS, GO:0033791=IEA, GO:0050660=IEA, GO:0005102=IPI, GO:0044281=TAS, GO:0003997=TAS, GO:0006631=IEA, GO:0003995=IEA, GO:0008206=TAS, GO:0033540=TAS, GO:0044255=TAS, GO:0005777=IEA} bile acid biosynthetic process, bile acid metabolic process, cellular lipid metabolic process, fatty acid beta-oxidation, fatty acid beta-oxidation using acyl-CoA oxidase, fatty acid metabolic process, small molecule metabolic process peroxisomal matrix, peroxisome 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity, acyl-CoA dehydrogenase activity, acyl-CoA oxidase activity, flavin adenine dinucleotide binding, pristanoyl-CoA oxidase activity, receptor binding Human ACOX3 Reactome UniProtKB {GO:0005739=GO_REF:0000019, GO:0016402=Reactome:REACT_16962, GO:0005782=Reactome:REACT_16962, GO:0050660=GO_REF:0000002, GO:0005102=PMID:20178365, GO:0006631=GO_REF:0000002, GO:0003997=GO_REF:0000002, GO:0003995=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0033540=Reactome:REACT_17017, GO:0044255=Reactome:REACT_16957, GO:0005777=GO_REF:0000002} O15254 Peroxisomal acyl-coenzyme A oxidase 3 protein 20130213 {GO:0005739=IEA, GO:0016402=TAS, GO:0005782=TAS, GO:0050660=IEA, GO:0005102=IPI, GO:0006631=IEA, GO:0003997=IEA, GO:0003995=IEA, GO:0044281=TAS, GO:0033540=TAS, GO:0044255=TAS, GO:0005777=IEA} cellular lipid metabolic process, fatty acid beta-oxidation using acyl-CoA oxidase, fatty acid metabolic process, small molecule metabolic process mitochondrion, peroxisomal matrix, peroxisome acyl-CoA dehydrogenase activity, acyl-CoA oxidase activity, flavin adenine dinucleotide binding, pristanoyl-CoA oxidase activity, receptor binding Human ACOXL BHF-UCL UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0006635=GO_REF:0000002, GO:0050660=GO_REF:0000002, GO:0006631=GO_REF:0000002, GO:0003997=GO_REF:0000002, GO:0003995=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0016627=GO_REF:0000002, GO:0005777=GO_REF:0000002} Q9NUZ1 Acyl-coenzyme A oxidase-like protein protein 20120516 {GO:0003674=ND, GO:0008150=ND, GO:0006635=IEA, GO:0050660=IEA, GO:0006631=IEA, GO:0003997=IEA, GO:0003995=IEA, GO:0005575=ND, GO:0016627=IEA, GO:0005777=IEA} biological_process, fatty acid beta-oxidation, fatty acid metabolic process cellular_component, peroxisome acyl-CoA dehydrogenase activity, acyl-CoA oxidase activity, flavin adenine dinucleotide binding, molecular_function, oxidoreductase activity, acting on the CH-CH group of donors Human ACP1 HPA UniProtKB {GO:0005515=PMID:9499402, GO:0043005=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0017124=GO_REF:0000019, GO:0003993=GO_REF:0000003, GO:0009898=PMID:10940933, GO:0007268=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0004725=GO_REF:0000002, GO:0004726=GO_REF:0000002} P24666 Low molecular weight phosphotyrosine protein phosphatase protein 20090616 {GO:0005515=IPI, GO:0043005=IEA, GO:0005737=IDA, GO:0017124=IEA, GO:0003993=IEA, GO:0009898=IDA, GO:0007268=IEA, GO:0005634=IDA, GO:0004725=IEA, GO:0004726=IEA} synaptic transmission cytoplasm, internal side of plasma membrane, neuron projection, nucleus SH3 domain binding, acid phosphatase activity, non-membrane spanning protein tyrosine phosphatase activity, protein binding, protein tyrosine phosphatase activity Human ACP2 MGI UniProtKB {GO:0001501=GO_REF:0000019, GO:0003993=GO_REF:0000003, GO:0016021=GO_REF:0000037, GO:0005765=GO_REF:0000039, GO:0007040=GO_REF:0000019, GO:0005764=PMID:3160696, GO:0043202=GO_REF:0000039} P11117 Lysosomal acid phosphatase protein 20091111 {GO:0001501=IEA, GO:0003993=IEA, GO:0016021=IEA, GO:0005765=IEA, GO:0007040=IEA, GO:0005764=IDA, GO:0043202=IEA} lysosome organization, skeletal system development integral to membrane, lysosomal lumen, lysosomal membrane, lysosome acid phosphatase activity Human ACP5 Reactome UniProtKB {GO:0006771=Reactome:REACT_11070, GO:0016787=GO_REF:0000002, GO:0006766=Reactome:REACT_11193, GO:0003993=Reactome:REACT_11171, GO:0006767=Reactome:REACT_11238, GO:0044281=Reactome:REACT_111217, GO:0016021=PMID:2338077, GO:0005764=GO_REF:0000039, GO:0008198=PMID:15993892, GO:0005829=Reactome:REACT_11171, GO:0008199=PMID:15993892} P13686 Tartrate-resistant acid phosphatase type 5 protein 20071129 {GO:0006771=TAS, GO:0016787=IEA, GO:0006766=TAS, GO:0003993=TAS, GO:0006767=TAS, GO:0044281=TAS, GO:0016021=TAS, GO:0005764=IEA, GO:0008198=IDA, GO:0005829=TAS, GO:0008199=IDA} riboflavin metabolic process, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cytosol, integral to membrane, lysosome acid phosphatase activity, ferric iron binding, ferrous iron binding, hydrolase activity Human ACP6 MGI UniProtKB {GO:0006629=PMID:10506173, GO:0005739=GO_REF:0000019, GO:0005737=PMID:12010880, GO:0003993=GO_REF:0000003, GO:0005576=GO_REF:0000039} Q9NPH0 Lysophosphatidic acid phosphatase type 6 protein 20121231 {GO:0006629=TAS, GO:0005739=IEA, GO:0005737=IDA, GO:0003993=IEA, GO:0005576=IEA} lipid metabolic process cytoplasm, extracellular region, mitochondrion acid phosphatase activity Human ACPL2 UniProtKB UniProtKB {GO:0003993=GO_REF:0000003, GO:0005576=GO_REF:0000039} Q8TE99 Acid phosphatase-like protein 2 protein 20130413 {GO:0003993=IEA, GO:0005576=IEA} extracellular region acid phosphatase activity Human UniProtKB-SubCell:SL-0243 ACPP InterPro UniProtKB {GO:0033265=GO_REF:0000019, GO:0005886=PMID:17658863, GO:0005771=GO_REF:0000019, GO:0003993=GO_REF:0000002, GO:0031985=GO_REF:0000019, GO:0046085=GO_REF:0000019, GO:0045177=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0030175=GO_REF:0000019, GO:0005765=GO_REF:0000039, GO:0042803=GO_REF:0000019, GO:0042802=PMID:18083097, GO:0005622=PMID:17658863, GO:0006144=GO_REF:0000019, GO:0008253=GO_REF:0000003, GO:0016021=GO_REF:0000019, GO:0030141=GO_REF:0000019, GO:0009117=GO_REF:0000019} Q5FBY0 Prostatic acid phosphatase protein 20130413 {GO:0033265=IEA, GO:0005886=IDA, GO:0005771=IEA, GO:0003993=IEA, GO:0031985=IEA, GO:0046085=IEA, GO:0045177=IEA, GO:0005576=IEA, GO:0030175=IEA, GO:0005765=IEA, GO:0042803=IEA, GO:0042802=IPI, GO:0005622=IDA, GO:0006144=IEA, GO:0008253=IEA, GO:0016021=IEA, GO:0030141=IEA, GO:0009117=IEA} adenosine metabolic process, nucleotide metabolic process, purine nucleobase metabolic process Golgi cisterna, apical part of cell, extracellular region, filopodium, integral to membrane, intracellular, lysosomal membrane, multivesicular body, plasma membrane, secretory granule 5'-nucleotidase activity, acid phosphatase activity, choline binding, identical protein binding, protein homodimerization activity Human InterPro:IPR000560 ACR HGNC UniProtKB {GO:0005515=PMID:15950651, GO:0043159=PMID:12398221, GO:0004252=PMID:6802470, GO:0005507=PMID:6815104, GO:0005798=GO_REF:0000019, GO:0042806=GO_REF:0000024, GO:0007339=GO_REF:0000019, GO:0048545=GO_REF:0000019, GO:0003677=PMID:1937464, GO:0005537=PMID:15950652, GO:0007338=GO_REF:0000024, GO:0009607=GO_REF:0000019, GO:0007190=PMID:3880736, GO:0043234=PMID:7521127, GO:0004040=GO_REF:0000024, GO:0002077=PMID:10418103, GO:0008144=GO_REF:0000024, GO:0006508=GO_REF:0000002, GO:0007341=PMID:10369396, GO:0008270=PMID:6815104, GO:0007340=PMID:2550339} P10323 Acrosin protein 20060428 {GO:0005515=IPI, GO:0043159=TAS, GO:0004252=IDA, GO:0005507=NAS, GO:0005798=IEA, GO:0042806=ISS, GO:0007339=IEA, GO:0048545=IEA, GO:0003677=NAS, GO:0005537=IDA, GO:0007338=ISS, GO:0009607=IEA, GO:0007190=IDA, GO:0043234=IDA, GO:0004040=ISS, GO:0002077=NAS, GO:0008144=ISS, GO:0006508=IEA, GO:0007341=IDA, GO:0008270=NAS, GO:0007340=IMP} acrosome matrix dispersal, acrosome reaction, activation of adenylate cyclase activity, binding of sperm to zona pellucida, penetration of zona pellucida, proteolysis, response to biotic stimulus, response to steroid hormone stimulus, single fertilization Golgi-associated vesicle, acrosomal matrix, protein complex DNA binding, amidase activity, copper ion binding, drug binding, fucose binding, mannose binding, protein binding, serine-type endopeptidase activity, zinc ion binding Human ACRBP UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0001669=GO_REF:0000039, GO:0005576=GO_REF:0000039, GO:0005575=GO_REF:0000015} Q8NEB7 Acrosin-binding protein protein 20061114 {GO:0003674=ND, GO:0008150=ND, GO:0001669=IEA, GO:0005576=IEA, GO:0005575=ND} biological_process acrosomal vesicle, cellular_component, extracellular region molecular_function Human ACSBG1 HGNC UniProtKB {GO:0000038=PMID:10954726, GO:0001676=PMID:10954726, GO:0005737=PMID:10954726, GO:0001552=GO_REF:0000019, GO:0005783=GO_REF:0000039, GO:0042552=PMID:10954726, GO:0016023=GO_REF:0000039, GO:0051384=GO_REF:0000019, GO:0031957=PMID:10954726, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0004467=PMID:10954726} Q96GR2 Long-chain-fatty-acid--CoA ligase ACSBG1 protein 20090803 {GO:0000038=IDA, GO:0001676=IDA, GO:0005737=IDA, GO:0001552=IEA, GO:0005783=IEA, GO:0042552=NAS, GO:0016023=IEA, GO:0051384=IEA, GO:0031957=IDA, GO:0003824=IEA, GO:0005524=IEA, GO:0004467=IDA} long-chain fatty acid metabolic process, myelination, ovarian follicle atresia, response to glucocorticoid stimulus, very long-chain fatty acid metabolic process cytoplasm, cytoplasmic membrane-bounded vesicle, endoplasmic reticulum ATP binding, catalytic activity, long-chain fatty acid-CoA ligase activity, very long-chain fatty acid-CoA ligase activity Human ACSBG2 GOC UniProtKB {GO:0047617=PMID:16762313, GO:0005739=PMID:16762313, GO:0001676=PMID:16371355, GO:0005737=GO_REF:0000052, GO:0016020=GO_REF:0000039, GO:0006631=PMID:16762313, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0004467=PMID:16371355} Q5FVE4 Long-chain-fatty-acid--CoA ligase ACSBG2 protein 20130413 {GO:0047617=IDA, GO:0005739=IDA, GO:0001676=IDA, GO:0005737=IDA, GO:0016020=IEA, GO:0006631=IDA, GO:0007275=IEA, GO:0007283=IEA, GO:0003824=IEA, GO:0005524=IEA, GO:0030154=IEA, GO:0004467=IDA} cell differentiation, fatty acid metabolic process, long-chain fatty acid metabolic process, multicellular organismal development, spermatogenesis cytoplasm, membrane, mitochondrion ATP binding, acyl-CoA hydrolase activity, catalytic activity, long-chain fatty acid-CoA ligase activity Human ACSF2 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0016874=GO_REF:0000037, GO:0006631=GO_REF:0000037, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q96CM8 Acyl-CoA synthetase family member 2, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0016874=IEA, GO:0006631=IEA, GO:0003824=IEA, GO:0005524=IEA} fatty acid metabolic process mitochondrion ATP binding, catalytic activity, ligase activity Human UniProtKB-SubCell:SL-0173 ACSF3 UniProtKB UniProtKB {GO:0005739=PMID:21846720, GO:0090409=PMID:21642549, GO:0006631=PMID:17762044, GO:0006633=PMID:21846720, GO:0090410=PMID:21642549, GO:0003824=GO_REF:0000002, GO:0016878=PMID:17762044, GO:0005524=GO_REF:0000037} Q4G176 Acyl-CoA synthetase family member 3, mitochondrial protein 20120112 {GO:0005739=IDA, GO:0090409=IDA, GO:0006631=IDA, GO:0006633=IDA, GO:0090410=IDA, GO:0003824=IEA, GO:0016878=IDA, GO:0005524=IEA} fatty acid biosynthetic process, fatty acid metabolic process, malonate catabolic process mitochondrion ATP binding, acid-thiol ligase activity, catalytic activity, malonyl-CoA synthetase activity Human ACSL1 Reactome UniProtKB {GO:0014070=GO_REF:0000019, GO:0001676=PMID:22022213, GO:0005886=GO_REF:0000019, GO:0071902=GO_REF:0000019, GO:0033211=GO_REF:0000019, GO:0005783=GO_REF:0000019, GO:0016874=GO_REF:0000038, GO:0005741=Reactome:REACT_115978, GO:0044281=Reactome:REACT_111217, GO:0035338=Reactome:REACT_1319, GO:0003824=GO_REF:0000002, GO:0005739=PMID:22022213, GO:0019432=Reactome:REACT_1190, GO:0044539=PMID:22022213, GO:0044255=Reactome:REACT_22279, GO:0005778=GO_REF:0000039, GO:0008610=PMID:21242590, GO:0007584=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0042178=GO_REF:0000019, GO:0034201=GO_REF:0000019, GO:0036109=Reactome:REACT_121147, GO:0005524=GO_REF:0000037, GO:0004467=Reactome:REACT_121204, GO:0033559=Reactome:REACT_121284, GO:0043651=Reactome:REACT_121100, GO:0005789=Reactome:REACT_121204, GO:0006641=GO_REF:0000019, GO:0015908=GO_REF:0000019, GO:0016021=GO_REF:0000037} P33121 Long-chain-fatty-acid--CoA ligase 1 protein 20130213 {GO:0014070=IEA, GO:0001676=IDA, GO:0005886=IEA, GO:0071902=IEA, GO:0033211=IEA, GO:0005783=IEA, GO:0016874=IEA, GO:0005741=TAS, GO:0044281=TAS, GO:0035338=TAS, GO:0003824=IEA, GO:0005739=IDA, GO:0019432=TAS, GO:0044539=IDA, GO:0044255=TAS, GO:0005778=IEA, GO:0008610=IDA, GO:0007584=IEA, GO:0042493=IEA, GO:0042178=IEA, GO:0034201=IEA, GO:0036109=TAS, GO:0005524=IEA, GO:0004467=TAS, GO:0033559=TAS, GO:0043651=TAS, GO:0005789=TAS, GO:0006641=IEA, GO:0015908=IEA, GO:0016021=IEA} adiponectin-mediated signaling pathway, alpha-linolenic acid metabolic process, cellular lipid metabolic process, fatty acid transport, linoleic acid metabolic process, lipid biosynthetic process, long-chain fatty acid import, long-chain fatty acid metabolic process, long-chain fatty-acyl-CoA biosynthetic process, positive regulation of protein serine/threonine kinase activity, response to drug, response to nutrient, response to oleic acid, response to organic cyclic compound, small molecule metabolic process, triglyceride biosynthetic process, triglyceride metabolic process, unsaturated fatty acid metabolic process, xenobiotic catabolic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, mitochondrial outer membrane, mitochondrion, peroxisomal membrane, plasma membrane ATP binding, catalytic activity, ligase activity, long-chain fatty acid-CoA ligase activity Human ACSL3 UniProtKB UniProtKB {GO:0014070=GO_REF:0000019, GO:0048471=PMID:20605918, GO:0005794=PMID:20605918, GO:0019901=PMID:20605918, GO:0005783=PMID:20605918, GO:0007584=GO_REF:0000019, GO:0019904=PMID:20605918, GO:0005741=GO_REF:0000039, GO:0034379=PMID:18003621, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:2001247=PMID:18003621, GO:0004467=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0006633=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0044539=PMID:20219900, GO:0005778=GO_REF:0000039} O95573 Long-chain-fatty-acid--CoA ligase 3 protein 20121022 {GO:0014070=IEA, GO:0048471=IDA, GO:0005794=IDA, GO:0019901=IPI, GO:0005783=IDA, GO:0007584=IEA, GO:0019904=IPI, GO:0005741=IEA, GO:0034379=IMP, GO:0003824=IEA, GO:0005524=IEA, GO:2001247=IMP, GO:0004467=IEA, GO:0007420=IEA, GO:0005789=IEA, GO:0006633=IEA, GO:0016021=IEA, GO:0044539=IDA, GO:0005778=IEA} brain development, fatty acid biosynthetic process, long-chain fatty acid import, positive regulation of phosphatidylcholine biosynthetic process, response to nutrient, response to organic cyclic compound, very-low-density lipoprotein particle assembly Golgi apparatus, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, mitochondrial outer membrane, perinuclear region of cytoplasm, peroxisomal membrane ATP binding, catalytic activity, long-chain fatty acid-CoA ligase activity, protein domain specific binding, protein kinase binding Human ACSL4 Reactome UniProtKB {GO:0006629=PMID:9598324, GO:0047676=PMID:9598324, GO:0031966=GO_REF:0000019, GO:0007584=GO_REF:0000019, GO:0060136=GO_REF:0000019, GO:0005741=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0035338=Reactome:REACT_1319, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0004467=PMID:10669417, GO:0005737=PMID:11889465, GO:0019432=Reactome:REACT_1190, GO:0005789=Reactome:REACT_22376, GO:0043025=GO_REF:0000019, GO:0006641=GO_REF:0000019, GO:0060996=GO_REF:0000019, GO:0070672=GO_REF:0000019, GO:0015908=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0044255=Reactome:REACT_22279, GO:0005778=GO_REF:0000039, GO:0005777=GO_REF:0000019} O60488 Long-chain-fatty-acid--CoA ligase 4 protein 20130301 {GO:0006629=IDA, GO:0047676=IDA, GO:0031966=IEA, GO:0007584=IEA, GO:0060136=IEA, GO:0005741=IEA, GO:0044281=TAS, GO:0035338=TAS, GO:0003824=IEA, GO:0005524=IEA, GO:0004467=IDA, GO:0005737=IDA, GO:0019432=TAS, GO:0005789=TAS, GO:0043025=IEA, GO:0006641=IEA, GO:0060996=IEA, GO:0070672=IEA, GO:0015908=IEA, GO:0016021=IEA, GO:0044255=TAS, GO:0005778=IEA, GO:0005777=IEA} cellular lipid metabolic process, dendritic spine development, embryonic process involved in female pregnancy, fatty acid transport, lipid metabolic process, long-chain fatty-acyl-CoA biosynthetic process, response to interleukin-15, response to nutrient, small molecule metabolic process, triglyceride biosynthetic process, triglyceride metabolic process cytoplasm, endoplasmic reticulum membrane, integral to membrane, mitochondrial membrane, mitochondrial outer membrane, neuronal cell body, peroxisomal membrane, peroxisome ATP binding, arachidonate-CoA ligase activity, catalytic activity, long-chain fatty acid-CoA ligase activity Human ACSL5 Reactome UniProtKB {GO:0016874=GO_REF:0000038, GO:0019432=Reactome:REACT_1190, GO:0005789=Reactome:REACT_22410, GO:0005743=GO_REF:0000019, GO:0005741=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0035338=Reactome:REACT_1319, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0044255=Reactome:REACT_22279, GO:0004467=GO_REF:0000003} Q9ULC5 Long-chain-fatty-acid--CoA ligase 5 protein 20130301 {GO:0016874=IEA, GO:0019432=TAS, GO:0005789=TAS, GO:0005743=IEA, GO:0005741=IEA, GO:0044281=TAS, GO:0035338=TAS, GO:0016021=IEA, GO:0005524=IEA, GO:0044255=TAS, GO:0004467=IEA} cellular lipid metabolic process, long-chain fatty-acyl-CoA biosynthetic process, small molecule metabolic process, triglyceride biosynthetic process endoplasmic reticulum membrane, integral to membrane, mitochondrial inner membrane, mitochondrial outer membrane ATP binding, ligase activity, long-chain fatty acid-CoA ligase activity Human ACSL6 Reactome UniProtKB {GO:0005886=PMID:10548543, GO:0005634=GO_REF:0000019, GO:0005741=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0035338=Reactome:REACT_1319, GO:0003824=GO_REF:0000002, GO:0042803=PMID:20429931, GO:0007405=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0048666=GO_REF:0000019, GO:0019432=Reactome:REACT_1190, GO:0044255=Reactome:REACT_22279, GO:0005778=GO_REF:0000039, GO:0001666=GO_REF:0000019, GO:0006637=PMID:10548543, GO:0032869=GO_REF:0000019, GO:0010867=GO_REF:0000019, GO:0007584=GO_REF:0000019, GO:0010747=GO_REF:0000019, GO:0008654=GO_REF:0000019, GO:0048545=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0004467=PMID:10548543, GO:0009629=GO_REF:0000019, GO:0010976=GO_REF:0000019, GO:0005789=Reactome:REACT_22247, GO:0006641=GO_REF:0000019, GO:0015908=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q9UKU0 Long-chain-fatty-acid--CoA ligase 6 protein 20130301 {GO:0005886=NAS, GO:0005634=IEA, GO:0005741=IEA, GO:0044281=TAS, GO:0035338=TAS, GO:0003824=IEA, GO:0042803=IDA, GO:0007405=IEA, GO:0005739=IEA, GO:0048666=IEA, GO:0019432=TAS, GO:0044255=TAS, GO:0005778=IEA, GO:0001666=IEA, GO:0006637=NAS, GO:0032869=IEA, GO:0010867=IEA, GO:0007584=IEA, GO:0010747=IEA, GO:0008654=IEA, GO:0048545=IEA, GO:0005524=IEA, GO:0004467=NAS, GO:0009629=IEA, GO:0010976=IEA, GO:0005789=TAS, GO:0006641=IEA, GO:0015908=IEA, GO:0016021=IEA} acyl-CoA metabolic process, cellular lipid metabolic process, cellular response to insulin stimulus, fatty acid transport, long-chain fatty-acyl-CoA biosynthetic process, neuroblast proliferation, neuron development, phospholipid biosynthetic process, positive regulation of neuron projection development, positive regulation of plasma membrane long-chain fatty acid transport, positive regulation of triglyceride biosynthetic process, response to gravity, response to hypoxia, response to nutrient, response to steroid hormone stimulus, small molecule metabolic process, triglyceride biosynthetic process, triglyceride metabolic process endoplasmic reticulum membrane, integral to membrane, mitochondrial outer membrane, mitochondrion, nucleus, peroxisomal membrane, plasma membrane ATP binding, catalytic activity, long-chain fatty acid-CoA ligase activity, protein homodimerization activity Human ACSM1 BHF-UCL UniProtKB {GO:0042632=PMID:15361761, GO:0019395=PMID:11470804, GO:0006805=Reactome:REACT_13433, GO:0044281=Reactome:REACT_111217, GO:0018874=PMID:11470804, GO:0003824=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0047760=PMID:11470804, GO:0005739=GO_REF:0000019, GO:0015645=GO_REF:0000019, GO:0005759=Reactome:REACT_6972, GO:0006633=GO_REF:0000019, GO:0003996=PMID:11470804, GO:0019605=PMID:11470804, GO:0015980=PMID:11470804} Q08AH1 Acyl-coenzyme A synthetase ACSM1, mitochondrial protein 20120516 {GO:0042632=NAS, GO:0019395=NAS, GO:0006805=TAS, GO:0044281=TAS, GO:0018874=NAS, GO:0003824=IEA, GO:0005525=IEA, GO:0005524=IEA, GO:0046872=IEA, GO:0047760=IDA, GO:0005739=IEA, GO:0015645=IEA, GO:0005759=TAS, GO:0006633=IEA, GO:0003996=IDA, GO:0019605=NAS, GO:0015980=NAS} benzoate metabolic process, butyrate metabolic process, cholesterol homeostasis, energy derivation by oxidation of organic compounds, fatty acid biosynthetic process, fatty acid oxidation, small molecule metabolic process, xenobiotic metabolic process mitochondrial matrix, mitochondrion ATP binding, GTP binding, acyl-CoA ligase activity, butyrate-CoA ligase activity, catalytic activity, fatty acid ligase activity, metal ion binding Human ACSM2B BHF-UCL UniProtKB {GO:0005739=PMID:19634011, GO:0003674=GO_REF:0000015, GO:0006805=Reactome:REACT_13433, GO:0005759=Reactome:REACT_6972, GO:0006631=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0047760=GO_REF:0000003, GO:0046872=GO_REF:0000037} Q68CK6 Acyl-coenzyme A synthetase ACSM2B, mitochondrial protein 20120516 {GO:0005739=NAS, GO:0003674=ND, GO:0006805=TAS, GO:0005759=TAS, GO:0006631=IEA, GO:0044281=TAS, GO:0003824=IEA, GO:0005524=IEA, GO:0047760=IEA, GO:0046872=IEA} fatty acid metabolic process, small molecule metabolic process, xenobiotic metabolic process mitochondrial matrix, mitochondrion ATP binding, butyrate-CoA ligase activity, catalytic activity, metal ion binding, molecular_function Human ACSM3 BHF-UCL UniProtKB {GO:0042632=PMID:15361761, GO:0003674=GO_REF:0000015, GO:0015645=GO_REF:0000019, GO:0005759=GO_REF:0000039, GO:0008217=PMID:7907320, GO:0006633=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0047760=GO_REF:0000003, GO:0046872=GO_REF:0000037} Q53FZ2 Acyl-coenzyme A synthetase ACSM3, mitochondrial protein 20120516 {GO:0042632=NAS, GO:0003674=ND, GO:0015645=IEA, GO:0005759=IEA, GO:0008217=NAS, GO:0006633=IEA, GO:0005575=ND, GO:0003824=IEA, GO:0005524=IEA, GO:0047760=IEA, GO:0046872=IEA} cholesterol homeostasis, fatty acid biosynthetic process, regulation of blood pressure cellular_component, mitochondrial matrix ATP binding, butyrate-CoA ligase activity, catalytic activity, fatty acid ligase activity, metal ion binding, molecular_function Human ACSM5 UniProtKB UniProtKB {GO:0005759=GO_REF:0000039, GO:0006631=GO_REF:0000037, GO:0005525=GO_REF:0000037, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0047760=GO_REF:0000003, GO:0046872=GO_REF:0000037} Q6NUN0 Acyl-coenzyme A synthetase ACSM5, mitochondrial protein 20130413 {GO:0005759=IEA, GO:0006631=IEA, GO:0005525=IEA, GO:0003824=IEA, GO:0005524=IEA, GO:0047760=IEA, GO:0046872=IEA} fatty acid metabolic process mitochondrial matrix ATP binding, GTP binding, butyrate-CoA ligase activity, catalytic activity, metal ion binding Human UniProtKB-SubCell:SL-0170 ACSS1 Reactome UniProtKB {GO:0005515=PMID:16788062, GO:0006805=Reactome:REACT_13705, GO:0016208=GO_REF:0000002, GO:0006069=Reactome:REACT_34, GO:0005759=Reactome:REACT_21284, GO:0019542=GO_REF:0000019, GO:0019427=GO_REF:0000002, GO:0019413=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0003987=PMID:16788062, GO:0006085=PMID:16788062, GO:0005524=GO_REF:0000037} Q9NUB1 Acetyl-coenzyme A synthetase 2-like, mitochondrial protein 20130301 {GO:0005515=IPI, GO:0006805=TAS, GO:0016208=IEA, GO:0006069=TAS, GO:0005759=TAS, GO:0019542=IEA, GO:0019427=IEA, GO:0019413=IEA, GO:0044281=TAS, GO:0003987=IDA, GO:0006085=IDA, GO:0005524=IEA} acetate biosynthetic process, acetyl-CoA biosynthetic process, acetyl-CoA biosynthetic process from acetate, ethanol oxidation, propionate biosynthetic process, small molecule metabolic process, xenobiotic metabolic process mitochondrial matrix AMP binding, ATP binding, acetate-CoA ligase activity, protein binding Human ACSS2 HPA UniProtKB {GO:0008610=PMID:10843999, GO:0006805=Reactome:REACT_13705, GO:0016208=PMID:10843999, GO:0006069=Reactome:REACT_34, GO:0019542=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0006085=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_553, GO:0043231=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0019427=GO_REF:0000002, GO:0019413=GO_REF:0000019, GO:0003987=PMID:10843999} Q9NR19 Acetyl-coenzyme A synthetase, cytoplasmic protein 20080818 {GO:0008610=IMP, GO:0006805=TAS, GO:0016208=IC, GO:0006069=TAS, GO:0019542=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0003824=IEA, GO:0006085=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0043231=IDA, GO:0005737=IDA, GO:0019427=IEA, GO:0019413=IEA, GO:0003987=IDA} acetate biosynthetic process, acetyl-CoA biosynthetic process, acetyl-CoA biosynthetic process from acetate, ethanol oxidation, lipid biosynthetic process, propionate biosynthetic process, small molecule metabolic process, xenobiotic metabolic process cytoplasm, cytosol, intracellular membrane-bounded organelle, nucleolus, nucleus AMP binding, ATP binding, acetate-CoA ligase activity, catalytic activity Human ACSS3 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0003987=GO_REF:0000003, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q9H6R3 Acyl-CoA synthetase short-chain family member 3, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0003987=IEA, GO:0003824=IEA, GO:0005524=IEA} mitochondrion ATP binding, acetate-CoA ligase activity, catalytic activity Human UniProtKB-SubCell:SL-0173 ACTA1 UniProtKB UniProtKB {GO:0005515=PMID:12849983, GO:0030240=PMID:11333380, GO:0001725=PMID:15198992, GO:0030049=Reactome:REACT_16969, GO:0005884=PMID:12849983, GO:0009991=GO_REF:0000019, GO:0048741=GO_REF:0000024, GO:0015629=PMID:15198992, GO:0048545=GO_REF:0000019, GO:0030017=PMID:1423520, GO:0005524=GO_REF:0000038, GO:0005829=Reactome:REACT_17057, GO:0009612=GO_REF:0000019, GO:0005737=GO_REF:0000038, GO:0010226=GO_REF:0000019, GO:0006936=PMID:10508519, GO:0043531=PMID:10508519, GO:0043503=GO_REF:0000019, GO:0005865=PMID:15198992, GO:0005200=PMID:10508519, GO:0016049=GO_REF:0000019, GO:0017022=PMID:10508519, GO:0005856=GO_REF:0000038} Q5T8M8 Actin, alpha skeletal muscle protein 20130413 {GO:0005515=IPI, GO:0030240=IMP, GO:0001725=IDA, GO:0030049=TAS, GO:0005884=IDA, GO:0009991=IEA, GO:0048741=ISS, GO:0015629=IMP, GO:0048545=IEA, GO:0030017=IDA, GO:0005524=IEA, GO:0005829=TAS, GO:0009612=IEA, GO:0005737=IEA, GO:0010226=IEA, GO:0006936=TAS, GO:0043531=TAS, GO:0043503=IEA, GO:0005865=IDA, GO:0005200=TAS, GO:0016049=IEA, GO:0017022=TAS, GO:0005856=IEA} cell growth, muscle contraction, muscle filament sliding, response to extracellular stimulus, response to lithium ion, response to mechanical stimulus, response to steroid hormone stimulus, skeletal muscle fiber adaptation, skeletal muscle fiber development, skeletal muscle thin filament assembly actin cytoskeleton, actin filament, cytoplasm, cytoskeleton, cytosol, sarcomere, stress fiber, striated muscle thin filament ADP binding, ATP binding, myosin binding, protein binding, structural constituent of cytoskeleton Human UniProtKB-KW:KW-0206 ACTA2 Reactome UniProtKB {GO:0043234=PMID:18468998, GO:0005737=PMID:12355421, GO:0006936=Reactome:REACT_20558, GO:0008217=GO_REF:0000019, GO:0009615=PMID:16548883, GO:0015629=GO_REF:0000019, GO:0072144=PMID:17464107, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_20663, GO:0030485=GO_REF:0000019, GO:0014829=GO_REF:0000019} P62736 Actin, aortic smooth muscle protein 20130301 {GO:0043234=IDA, GO:0005737=IDA, GO:0006936=TAS, GO:0008217=IEA, GO:0009615=IEP, GO:0015629=IEA, GO:0072144=IEP, GO:0005524=IEA, GO:0005829=TAS, GO:0030485=IEA, GO:0014829=IEA} glomerular mesangial cell development, muscle contraction, regulation of blood pressure, response to virus, vascular smooth muscle contraction actin cytoskeleton, cytoplasm, cytosol, protein complex, smooth muscle contractile fiber ATP binding Human ACTB BHF-UCL UniProtKB {GO:0050998=PMID:17502619, GO:0005515=PMID:21577206, GO:0030424=GO_REF:0000019, GO:0006928=PMID:16130169, GO:0007409=GO_REF:0000019, GO:0005829=Reactome:REACT_160291, GO:0005737=PMID:16130169, GO:0006457=Reactome:REACT_17004, GO:0007411=Reactome:REACT_18266, GO:0035267=PMID:10966108, GO:0005856=PMID:16130169, GO:0019901=GO_REF:0000019, GO:0034329=Reactome:REACT_20676, GO:0014069=GO_REF:0000019, GO:0030957=PMID:16687403, GO:0005524=GO_REF:0000037, GO:0045216=Reactome:REACT_19331, GO:0043234=GO_REF:0000019, GO:0070688=PMID:19377461, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0030529=PMID:17289661, GO:0005200=PMID:6202424, GO:0051084=Reactome:REACT_16952, GO:0030863=GO_REF:0000019, GO:0019894=PMID:18680169, GO:0038096=Reactome:REACT_160123, GO:0044267=Reactome:REACT_17015, GO:0016044=Reactome:REACT_11123, GO:0034332=Reactome:REACT_19195} P60709 Actin, cytoplasmic 1 protein 20110811 {GO:0050998=IPI, GO:0005515=IPI, GO:0030424=IEA, GO:0006928=TAS, GO:0007409=IEA, GO:0005829=TAS, GO:0005737=TAS, GO:0006457=TAS, GO:0007411=TAS, GO:0035267=IDA, GO:0005856=TAS, GO:0019901=IEA, GO:0034329=TAS, GO:0014069=IEA, GO:0030957=IPI, GO:0005524=IEA, GO:0045216=TAS, GO:0043234=IEA, GO:0070688=IDA, GO:0007596=TAS, GO:0045087=TAS, GO:0030529=IDA, GO:0005200=TAS, GO:0051084=TAS, GO:0030863=IEA, GO:0019894=IPI, GO:0038096=TAS, GO:0044267=TAS, GO:0016044=TAS, GO:0034332=TAS} 'de novo' posttranslational protein folding, Fc-gamma receptor signaling pathway involved in phagocytosis, adherens junction organization, axon guidance, axonogenesis, blood coagulation, cell junction assembly, cell-cell junction organization, cellular component movement, cellular membrane organization, cellular protein metabolic process, innate immune response, protein folding MLL5-L complex, NuA4 histone acetyltransferase complex, axon, cortical cytoskeleton, cytoplasm, cytoskeleton, cytosol, postsynaptic density, protein complex, ribonucleoprotein complex ATP binding, Tat protein binding, kinesin binding, nitric-oxide synthase binding, protein binding, protein kinase binding, structural constituent of cytoskeleton Human UniProtKB:P04608 ACTBL2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0005856=GO_REF:0000039, GO:0005524=GO_REF:0000037} Q562R1 Beta-actin-like protein 2 protein 20130413 {GO:0005737=IEA, GO:0005856=IEA, GO:0005524=IEA} cytoplasm, cytoskeleton ATP binding Human UniProtKB-SubCell:SL-0090 ACTC1 GOC UniProtKB {GO:0030048=PMID:16611632, GO:0030240=GO_REF:0000024, GO:0060047=PMID:17947298, GO:0042643=PMID:16611632, GO:0030049=Reactome:REACT_16969, GO:0006200=PMID:17765196, GO:0042493=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0005884=PMID:19799913, GO:0006915=GO_REF:0000024, GO:0031032=GO_REF:0000024, GO:0060048=GO_REF:0000019, GO:0030017=PMID:16288873, GO:0005524=PMID:16611632, GO:0033275=PMID:19799913, GO:0005829=Reactome:REACT_17057, GO:0005737=PMID:20962418, GO:0055003=GO_REF:0000024, GO:0017022=PMID:19799913, GO:0016887=PMID:16611632, GO:0055008=GO_REF:0000024, GO:0031674=GO_REF:0000024} P68032 Actin, alpha cardiac muscle 1 protein 20130413 {GO:0030048=IDA, GO:0030240=ISS, GO:0060047=IMP, GO:0042643=IDA, GO:0030049=TAS, GO:0006200=IDA, GO:0042493=IEA, GO:0045471=IEA, GO:0005884=IDA, GO:0006915=ISS, GO:0031032=ISS, GO:0060048=IEA, GO:0030017=IDA, GO:0005524=IDA, GO:0033275=IMP, GO:0005829=TAS, GO:0005737=IDA, GO:0055003=ISS, GO:0017022=IDA, GO:0016887=IDA, GO:0055008=ISS, GO:0031674=ISS} ATP catabolic process, actin filament-based movement, actin-myosin filament sliding, actomyosin structure organization, apoptotic process, cardiac muscle contraction, cardiac muscle tissue morphogenesis, cardiac myofibril assembly, heart contraction, muscle filament sliding, response to drug, response to ethanol, skeletal muscle thin filament assembly I band, actin filament, actomyosin, actin part, cytoplasm, cytosol, sarcomere ATP binding, ATPase activity, myosin binding Human ACTG1 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0034329=Reactome:REACT_20676, GO:0045214=GO_REF:0000019, GO:0006928=PMID:16130169, GO:0030016=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0045216=Reactome:REACT_19331, GO:0042802=PMID:16189514, GO:0005829=Reactome:REACT_160291, GO:0005737=GO_REF:0000038, GO:0031941=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0045087=Reactome:REACT_6802, GO:0005200=PMID:16130169, GO:0005856=PMID:16130169, GO:0038096=Reactome:REACT_160123, GO:0016044=Reactome:REACT_11123, GO:0034332=Reactome:REACT_19195, GO:0070062=PMID:21557262} P63261 Actin, cytoplasmic 2 protein 20130415 {GO:0005515=IPI, GO:0034329=TAS, GO:0045214=IEA, GO:0006928=TAS, GO:0030016=IEA, GO:0005524=IEA, GO:0045216=TAS, GO:0042802=IPI, GO:0005829=TAS, GO:0005737=IEA, GO:0031941=IEA, GO:0007411=TAS, GO:0045087=TAS, GO:0005200=IC, GO:0005856=TAS, GO:0038096=TAS, GO:0016044=TAS, GO:0034332=TAS, GO:0070062=IDA} Fc-gamma receptor signaling pathway involved in phagocytosis, adherens junction organization, axon guidance, cell junction assembly, cell-cell junction organization, cellular component movement, cellular membrane organization, innate immune response, sarcomere organization cytoplasm, cytoskeleton, cytosol, extracellular vesicular exosome, filamentous actin, myofibril ATP binding, identical protein binding, protein binding, structural constituent of cytoskeleton Human UniProtKB:P63261 ACTG2 Reactome UniProtKB {GO:0005737=GO_REF:0000038, GO:0006936=Reactome:REACT_20558, GO:0005856=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_20663, GO:0071944=GO_REF:0000019} P63267 Actin, gamma-enteric smooth muscle protein 20130301 {GO:0005737=IEA, GO:0006936=TAS, GO:0005856=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0071944=IEA} muscle contraction cell periphery, cytoplasm, cytoskeleton, cytosol ATP binding Human ACTL6A BHF-UCL UniProtKB {GO:0005515=PMID:18026119, GO:0003407=PMID:18816825, GO:0006357=PMID:8804307, GO:0005886=GO_REF:0000054, GO:0003713=PMID:8804307, GO:0005634=PMID:18026119, GO:0006310=GO_REF:0000037, GO:0071564=PMID:18816825, GO:0005524=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0007399=GO_REF:0000019, GO:0007165=PMID:9845365, GO:0031011=PMID:21303910, GO:0006281=GO_REF:0000037, GO:0016514=PMID:8804307, GO:0043967=PMID:14966270, GO:0003682=GO_REF:0000019, GO:0043968=PMID:14966270, GO:0035267=PMID:14966270, GO:0006338=PMID:18816825, GO:0040008=GO_REF:0000037} O96019 Actin-like protein 6A protein 20110811 {GO:0005515=IPI, GO:0003407=IEP, GO:0006357=NAS, GO:0005886=IDA, GO:0003713=NAS, GO:0005634=IDA, GO:0006310=IEA, GO:0071564=IDA, GO:0005524=IEA, GO:0006351=IEA, GO:0007399=IEA, GO:0007165=TAS, GO:0031011=IDA, GO:0006281=IEA, GO:0016514=IDA, GO:0043967=IDA, GO:0003682=IEA, GO:0043968=IDA, GO:0035267=IDA, GO:0006338=IC, GO:0040008=IEA} DNA recombination, DNA repair, chromatin remodeling, histone H2A acetylation, histone H4 acetylation, nervous system development, neural retina development, regulation of growth, regulation of transcription from RNA polymerase II promoter, signal transduction, transcription, DNA-dependent Ino80 complex, NuA4 histone acetyltransferase complex, SWI/SNF complex, npBAF complex, nucleus, plasma membrane ATP binding, chromatin binding, protein binding, transcription coactivator activity Human GO:0071564 ACTL6B HPA UniProtKB {GO:0071565=GO_REF:0000024, GO:0006357=PMID:8804307, GO:0016514=PMID:8804307, GO:0003713=PMID:8804307, GO:0005730=GO_REF:0000052, GO:0005200=PMID:10380635, GO:0006325=PMID:10380635, GO:0006338=PMID:11726552, GO:0005634=PMID:10380635, GO:0005524=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0007399=GO_REF:0000019} O94805 Actin-like protein 6B protein 20111111 {GO:0071565=ISS, GO:0006357=NAS, GO:0016514=IDA, GO:0003713=NAS, GO:0005730=IDA, GO:0005200=TAS, GO:0006325=NAS, GO:0006338=IDA, GO:0005634=IDA, GO:0005524=IEA, GO:0006351=IEA, GO:0007399=IEA} chromatin organization, chromatin remodeling, nervous system development, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent SWI/SNF complex, nBAF complex, nucleolus, nucleus ATP binding, structural constituent of cytoskeleton, transcription coactivator activity Human ACTL7A PINC UniProtKB {GO:0043234=PMID:21278383, GO:0005737=GO_REF:0000024, GO:0005794=GO_REF:0000024, GO:0005200=PMID:10373328, GO:0005856=GO_REF:0000039, GO:0001673=GO_REF:0000019} Q9Y615 Actin-like protein 7A protein 20030904 {GO:0043234=IDA, GO:0005737=ISS, GO:0005794=ISS, GO:0005200=TAS, GO:0005856=IEA, GO:0001673=IEA} Golgi apparatus, cytoplasm, cytoskeleton, male germ cell nucleus, protein complex structural constituent of cytoskeleton Human ACTL7B PINC UniProtKB {GO:0005737=GO_REF:0000019, GO:0005200=PMID:10373328, GO:0015629=PMID:10373328} Q9Y614 Actin-like protein 7B protein 20030904 {GO:0005737=IEA, GO:0005200=TAS, GO:0015629=TAS} actin cytoskeleton, cytoplasm structural constituent of cytoskeleton Human ACTL8 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005856=GO_REF:0000039} Q9H568 Actin-like protein 8 protein 20100326 {GO:0005737=IDA, GO:0005856=IEA} cytoplasm, cytoskeleton Human ACTN1 BHF-UCL UniProtKB {GO:0005515=PMID:16291744, GO:0030018=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0005634=GO_REF:0000019, GO:0042995=PMID:16464232, GO:0005829=Reactome:REACT_20671, GO:0031143=PMID:1629252, GO:0005916=GO_REF:0000019, GO:0005737=PMID:16464232, GO:0051015=GO_REF:0000019, GO:0043197=GO_REF:0000019, GO:0048041=PMID:16807302, GO:0031093=Reactome:REACT_21351, GO:0051764=GO_REF:0000002, GO:0005856=GO_REF:0000039, GO:0051017=GO_REF:0000019, GO:0034329=Reactome:REACT_20676, GO:0019904=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0030168=Reactome:REACT_798, GO:0003779=GO_REF:0000038, GO:0042981=PMID:16807302, GO:0005576=Reactome:REACT_21351, GO:0001726=GO_REF:0000039, GO:0044325=PMID:17944866, GO:0005178=PMID:7983147, GO:0007596=Reactome:REACT_604, GO:0017166=PMID:15988023, GO:0002576=Reactome:REACT_318, GO:0051271=PMID:7983147, GO:0005925=PMID:16807302} P12814 Alpha-actinin-1 protein 20120119 {GO:0005515=IPI, GO:0030018=IEA, GO:0005886=IEA, GO:0005634=IEA, GO:0042995=IDA, GO:0005829=TAS, GO:0031143=TAS, GO:0005916=IEA, GO:0005737=IDA, GO:0051015=IEA, GO:0043197=IEA, GO:0048041=IMP, GO:0031093=TAS, GO:0051764=IEA, GO:0005856=IEA, GO:0051017=IEA, GO:0034329=TAS, GO:0019904=IEA, GO:0005509=IEA, GO:0030168=TAS, GO:0003779=IEA, GO:0042981=NAS, GO:0005576=TAS, GO:0001726=IEA, GO:0044325=IPI, GO:0005178=IDA, GO:0007596=TAS, GO:0017166=IPI, GO:0002576=TAS, GO:0051271=IMP, GO:0005925=IMP} actin crosslink formation, actin filament bundle assembly, blood coagulation, cell junction assembly, focal adhesion assembly, negative regulation of cellular component movement, platelet activation, platelet degranulation, regulation of apoptotic process Z disc, cell projection, cytoplasm, cytoskeleton, cytosol, dendritic spine, extracellular region, fascia adherens, focal adhesion, nucleus, plasma membrane, platelet alpha granule lumen, pseudopodium, ruffle actin binding, actin filament binding, calcium ion binding, integrin binding, ion channel binding, protein binding, protein domain specific binding, vinculin binding Human UniProtKB:Q9P0L9 ACTN2 BHF-UCL UniProtKB {GO:0005515=PMID:11309420, GO:0008092=PMID:10427098, GO:0030018=PMID:19932097, GO:0030035=PMID:12356918, GO:0005884=PMID:1339456, GO:0043267=PMID:10812072, GO:0043268=PMID:17110593, GO:0007268=Reactome:REACT_13685, GO:0030175=PMID:12356918, GO:0051373=PMID:11699871, GO:0042802=PMID:11101506, GO:0005829=Reactome:REACT_20670, GO:0031143=PMID:1629252, GO:0030375=GO_REF:0000019, GO:0006936=GO_REF:0000019, GO:0051015=GO_REF:0000019, GO:0043197=PMID:15841212, GO:0051289=PMID:9501083, GO:0048041=PMID:16807302, GO:0042391=PMID:10812072, GO:0046983=PMID:9501083, GO:0031093=Reactome:REACT_21351, GO:0051764=GO_REF:0000002, GO:0005856=PMID:12809483, GO:0008307=PMID:1339456, GO:0007155=PMID:10656685, GO:0051017=GO_REF:0000002, GO:0030049=Reactome:REACT_16969, GO:0005509=GO_REF:0000002, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_21351, GO:0003779=GO_REF:0000038, GO:0042981=PMID:16807302, GO:0044325=PMID:10812072, GO:0031432=PMID:11846417, GO:0005178=PMID:8104223, GO:0007596=Reactome:REACT_604, GO:1901018=PMID:17110593, GO:0002576=Reactome:REACT_318, GO:0005925=PMID:16807302, GO:0070080=PMID:11846417} P35609 Alpha-actinin-2 protein 20120919 {GO:0005515=IPI, GO:0008092=IDA, GO:0030018=IDA, GO:0030035=IDA, GO:0005884=TAS, GO:0043267=IMP, GO:0043268=IDA, GO:0007268=TAS, GO:0030175=IDA, GO:0051373=IDA, GO:0042802=IPI, GO:0005829=TAS, GO:0031143=TAS, GO:0030375=IEA, GO:0006936=IEA, GO:0051015=IEA, GO:0043197=TAS, GO:0051289=IDA, GO:0048041=IMP, GO:0042391=IMP, GO:0046983=IDA, GO:0031093=TAS, GO:0051764=IEA, GO:0005856=NAS, GO:0008307=TAS, GO:0007155=TAS, GO:0051017=IEA, GO:0030049=TAS, GO:0005509=IEA, GO:0030168=TAS, GO:0005576=TAS, GO:0003779=IEA, GO:0042981=NAS, GO:0044325=IPI, GO:0031432=IPI, GO:0005178=TAS, GO:0007596=TAS, GO:1901018=IDA, GO:0002576=TAS, GO:0005925=IMP, GO:0070080=IPI} actin crosslink formation, actin filament bundle assembly, blood coagulation, cell adhesion, focal adhesion assembly, microspike assembly, muscle contraction, muscle filament sliding, negative regulation of potassium ion transport, platelet activation, platelet degranulation, positive regulation of potassium ion transmembrane transporter activity, positive regulation of potassium ion transport, protein homotetramerization, regulation of apoptotic process, regulation of membrane potential, synaptic transmission Z disc, actin filament, cytoskeleton, cytosol, dendritic spine, extracellular region, filopodium, focal adhesion, platelet alpha granule lumen, pseudopodium FATZ binding, actin binding, actin filament binding, calcium ion binding, cytoskeletal protein binding, identical protein binding, integrin binding, ion channel binding, protein binding, protein dimerization activity, structural constituent of muscle, thyroid hormone receptor coactivator activity, titin Z domain binding, titin binding Human ACTN3 BHF-UCL UniProtKB {GO:0005515=PMID:11309420, GO:0030049=Reactome:REACT_16969, GO:0005884=PMID:1339456, GO:0005509=GO_REF:0000002, GO:0003779=GO_REF:0000037, GO:0042981=PMID:16807302, GO:0042803=PMID:15841212, GO:0005829=Reactome:REACT_17057, GO:0031143=PMID:1629252, GO:0005178=PMID:8104223, GO:0048041=PMID:16807302, GO:0051764=GO_REF:0000002, GO:0008307=PMID:1339456, GO:0051017=GO_REF:0000002, GO:0005925=PMID:16807302} Q08043 Alpha-actinin-3 protein 20110808 {GO:0005515=IPI, GO:0030049=TAS, GO:0005884=TAS, GO:0005509=IEA, GO:0003779=IEA, GO:0042981=NAS, GO:0042803=TAS, GO:0005829=TAS, GO:0031143=TAS, GO:0005178=TAS, GO:0048041=IMP, GO:0051764=IEA, GO:0008307=TAS, GO:0051017=IEA, GO:0005925=IMP} actin crosslink formation, actin filament bundle assembly, focal adhesion assembly, muscle filament sliding, regulation of apoptotic process actin filament, cytosol, focal adhesion, pseudopodium actin binding, calcium ion binding, integrin binding, protein binding, protein homodimerization activity, structural constituent of muscle Human UniProtKB:Q86TC9 ACTN4 IntAct UniProtKB {GO:0005515=PMID:16944923, GO:0030018=GO_REF:0000019, GO:0048471=PMID:15619032, GO:0032417=PMID:11948184, GO:0005634=PMID:9508771, GO:0015031=GO_REF:0000037, GO:0042803=PMID:15841212, GO:0031143=PMID:1629252, GO:0005737=PMID:9508771, GO:0051015=PMID:12411747, GO:0001882=PMID:12411747, GO:0031093=Reactome:REACT_21351, GO:0051764=GO_REF:0000002, GO:0051017=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0048549=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_21351, GO:0003779=PMID:8104223, GO:0042981=PMID:16807302, GO:0043234=PMID:11948184, GO:0047485=GO_REF:0000019, GO:0005178=PMID:8104223, GO:0007596=Reactome:REACT_604, GO:0030529=PMID:17289661, GO:0002576=Reactome:REACT_318, GO:0030863=GO_REF:0000019, GO:0051271=GO_REF:0000019, GO:0051272=PMID:15048094} O43707 Alpha-actinin-4 protein 20130415 {GO:0005515=IPI, GO:0030018=IEA, GO:0048471=IDA, GO:0032417=NAS, GO:0005634=IDA, GO:0015031=IEA, GO:0042803=TAS, GO:0031143=TAS, GO:0005737=IDA, GO:0051015=IDA, GO:0001882=IDA, GO:0031093=TAS, GO:0051764=IEA, GO:0051017=IEA, GO:0001666=IEA, GO:0005509=IEA, GO:0048549=IEA, GO:0030168=TAS, GO:0005576=TAS, GO:0003779=TAS, GO:0042981=NAS, GO:0043234=IDA, GO:0047485=IEA, GO:0005178=TAS, GO:0007596=TAS, GO:0030529=IDA, GO:0002576=TAS, GO:0030863=IEA, GO:0051271=IEA, GO:0051272=IMP} actin crosslink formation, actin filament bundle assembly, blood coagulation, negative regulation of cellular component movement, platelet activation, platelet degranulation, positive regulation of cellular component movement, positive regulation of pinocytosis, positive regulation of sodium:hydrogen antiporter activity, protein transport, regulation of apoptotic process, response to hypoxia Z disc, cortical cytoskeleton, cytoplasm, extracellular region, nucleus, perinuclear region of cytoplasm, platelet alpha granule lumen, protein complex, pseudopodium, ribonucleoprotein complex actin binding, actin filament binding, calcium ion binding, integrin binding, nucleoside binding, protein N-terminus binding, protein binding, protein homodimerization activity Human UniProtKB:Q07157 ACTR10 ENSEMBL UniProtKB {GO:0005737=GO_REF:0000037, GO:0005869=GO_REF:0000019, GO:0007018=GO_REF:0000019} Q9NZ32 Actin-related protein 10 protein 20130413 {GO:0005737=IEA, GO:0005869=IEA, GO:0007018=IEA} microtubule-based movement cytoplasm, dynactin complex Human Ensembl:ENSMUSP00000021479 ACTR1A LIFEdb UniProtKB {GO:0019886=Reactome:REACT_121399, GO:0005813=PMID:21399614, GO:0005737=GO_REF:0000054, GO:0000086=Reactome:REACT_2203, GO:0005875=PMID:7696711, GO:0000278=Reactome:REACT_152, GO:0016192=PMID:1528266, GO:0005869=PMID:7696711, GO:0005856=GO_REF:0000038, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_120995} P61163 Alpha-centractin protein 20100607 {GO:0019886=TAS, GO:0005813=IDA, GO:0005737=IDA, GO:0000086=TAS, GO:0005875=TAS, GO:0000278=TAS, GO:0016192=TAS, GO:0005869=TAS, GO:0005856=IEA, GO:0005524=IEA, GO:0005829=TAS} G2/M transition of mitotic cell cycle, antigen processing and presentation of exogenous peptide antigen via MHC class II, mitotic cell cycle, vesicle-mediated transport centrosome, cytoplasm, cytoskeleton, cytosol, dynactin complex, microtubule associated complex ATP binding Human ACTR1B IntAct UniProtKB {GO:0005515=PMID:12857853, GO:0019886=Reactome:REACT_121399, GO:0005737=GO_REF:0000054, GO:0005813=PMID:21399614, GO:0005869=PMID:7696711, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_120995} P42025 Beta-centractin protein 20130415 {GO:0005515=IPI, GO:0019886=TAS, GO:0005737=IDA, GO:0005813=IDA, GO:0005869=TAS, GO:0005524=IEA, GO:0005829=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II centrosome, cytoplasm, cytosol, dynactin complex ATP binding, protein binding Human UniProtKB:Q9QZB7 ACTR2 Reactome UniProtKB {GO:0034314=GO_REF:0000002, GO:0005885=PMID:19641626, GO:0045087=Reactome:REACT_6802, GO:0006928=PMID:9230079, GO:0003779=GO_REF:0000037, GO:0042995=GO_REF:0000039, GO:0015629=PMID:9230079, GO:0038096=Reactome:REACT_160123, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_160291} P61160 Actin-related protein 2 protein 20130213 {GO:0034314=IEA, GO:0005885=RCA, GO:0045087=TAS, GO:0006928=TAS, GO:0003779=IEA, GO:0042995=IEA, GO:0015629=TAS, GO:0038096=TAS, GO:0005524=IEA, GO:0005829=TAS} Arp2/3 complex-mediated actin nucleation, Fc-gamma receptor signaling pathway involved in phagocytosis, cellular component movement, innate immune response Arp2/3 protein complex, actin cytoskeleton, cell projection, cytosol ATP binding, actin binding Human ACTR3 IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0034314=GO_REF:0000002, GO:0030056=GO_REF:0000019, GO:0005885=PMID:9230079, GO:0002102=GO_REF:0000019, GO:0051491=GO_REF:0000019, GO:0006928=PMID:9230079, GO:0015629=PMID:9230079, GO:0005829=Reactome:REACT_160291, GO:0010592=GO_REF:0000019, GO:0009743=GO_REF:0000019, GO:0046677=GO_REF:0000019, GO:0008356=GO_REF:0000019, GO:0033206=GO_REF:0000019, GO:0051321=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0060076=GO_REF:0000019, GO:0030027=GO_REF:0000019, GO:0051653=GO_REF:0000019, GO:0007163=GO_REF:0000019, GO:0000139=GO_REF:0000019, GO:0045666=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0050775=GO_REF:0000019, GO:0060271=PMID:20393563, GO:0038096=Reactome:REACT_160123, GO:0043519=GO_REF:0000019} P61158 Actin-related protein 3 protein 20130415 {GO:0005515=IPI, GO:0034314=IEA, GO:0030056=IEA, GO:0005885=TAS, GO:0002102=IEA, GO:0051491=IEA, GO:0006928=TAS, GO:0015629=TAS, GO:0005829=TAS, GO:0010592=IEA, GO:0009743=IEA, GO:0046677=IEA, GO:0008356=IEA, GO:0033206=IEA, GO:0051321=IEA, GO:0003779=IEA, GO:0005524=IEA, GO:0060076=IEA, GO:0030027=IEA, GO:0051653=IEA, GO:0007163=IEA, GO:0000139=IEA, GO:0045666=IEA, GO:0045087=TAS, GO:0050775=IEA, GO:0060271=IMP, GO:0038096=TAS, GO:0043519=IEA} Arp2/3 complex-mediated actin nucleation, Fc-gamma receptor signaling pathway involved in phagocytosis, asymmetric cell division, cellular component movement, cilium morphogenesis, cytokinesis after meiosis, establishment or maintenance of cell polarity, innate immune response, meiotic cell cycle, positive regulation of dendrite morphogenesis, positive regulation of filopodium assembly, positive regulation of lamellipodium assembly, positive regulation of neuron differentiation, regulation of myosin II filament organization, response to antibiotic, response to carbohydrate stimulus, spindle localization Arp2/3 protein complex, Golgi membrane, actin cytoskeleton, cytosol, excitatory synapse, hemidesmosome, lamellipodium, podosome ATP binding, actin binding, protein binding Human UniProtKB:P17535 ACTR3B UniProtKB UniProtKB {GO:0034314=GO_REF:0000002, GO:0005737=GO_REF:0000037, GO:0005885=GO_REF:0000002, GO:0003779=GO_REF:0000037, GO:0042995=GO_REF:0000039, GO:0005524=GO_REF:0000037} Q9P1U1 Actin-related protein 3B protein 20130413 {GO:0034314=IEA, GO:0005737=IEA, GO:0005885=IEA, GO:0003779=IEA, GO:0042995=IEA, GO:0005524=IEA} Arp2/3 complex-mediated actin nucleation Arp2/3 protein complex, cell projection, cytoplasm ATP binding, actin binding Human UniProtKB-SubCell:SL-0280 ACTR5 IntAct UniProtKB {GO:0005515=PMID:20855601, GO:0031011=PMID:21303910, GO:0005737=PMID:19014934, GO:0006355=GO_REF:0000037, GO:0070914=PMID:20855601, GO:0005634=PMID:19014934, GO:0006310=GO_REF:0000037, GO:0005524=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0006302=PMID:19014934} Q9H9F9 Actin-related protein 5 protein 20130415 {GO:0005515=IPI, GO:0031011=IDA, GO:0005737=IDA, GO:0006355=IEA, GO:0070914=IMP, GO:0005634=IDA, GO:0006310=IEA, GO:0005524=IEA, GO:0006351=IEA, GO:0006302=IMP} DNA recombination, UV-damage excision repair, double-strand break repair, regulation of transcription, DNA-dependent, transcription, DNA-dependent Ino80 complex, cytoplasm, nucleus ATP binding, protein binding Human UniProtKB:Q16531 ACTR6 UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0005856=GO_REF:0000039} Q9GZN1 Actin-related protein 6 protein 20130413 {GO:0005737=IEA, GO:0005856=IEA} cytoplasm, cytoskeleton Human UniProtKB-SubCell:SL-0090 ACTR8 IntAct UniProtKB {GO:0005515=PMID:18163988, GO:0031011=PMID:21303910, GO:0007067=GO_REF:0000037, GO:0006355=GO_REF:0000037, GO:0006281=GO_REF:0000037, GO:0005634=PMID:18026119, GO:0006310=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0051301=GO_REF:0000037} Q9H981 Actin-related protein 8 protein 20130415 {GO:0005515=IPI, GO:0031011=IDA, GO:0007067=IEA, GO:0006355=IEA, GO:0006281=IEA, GO:0005634=IDA, GO:0006310=IEA, GO:0005524=IEA, GO:0006351=IEA, GO:0051301=IEA} DNA recombination, DNA repair, cell division, mitosis, regulation of transcription, DNA-dependent, transcription, DNA-dependent Ino80 complex, nucleus ATP binding, protein binding Human UniProtKB:Q9H9F9 ACVR1 BHF-UCL UniProtKB {GO:0005515=PMID:18436533, GO:0003289=PMID:19506109, GO:0001655=GO_REF:0000019, GO:0001755=GO_REF:0000019, GO:0003183=PMID:19506109, GO:0046332=PMID:12065756, GO:0007281=GO_REF:0000019, GO:0042803=PMID:18436533, GO:0007507=GO_REF:0000019, GO:0003143=PMID:19506109, GO:0004702=GO_REF:0000019, GO:0007179=PMID:8242742, GO:0009968=PMID:9884026, GO:0002526=GO_REF:0000019, GO:0001707=GO_REF:0000019, GO:0030501=PMID:18436533, GO:0032926=PMID:9884026, GO:0030509=PMID:18436533, GO:0032924=PMID:19506109, GO:0001701=GO_REF:0000019, GO:0060923=PMID:19506109, GO:0001702=GO_REF:0000019, GO:0060037=GO_REF:0000019, GO:0048641=GO_REF:0000019, GO:0071385=GO_REF:0000019, GO:0005887=PMID:8242742, GO:0048179=PMID:8242742, GO:0060389=PMID:19736306, GO:0045893=PMID:8242742, GO:0051145=GO_REF:0000019, GO:0016361=PMID:8242742, GO:0007368=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0000082=PMID:9884026, GO:0030278=PMID:16642017, GO:0048185=PMID:8242742, GO:0045944=PMID:19506109, GO:0005025=GO_REF:0000019, GO:0050431=PMID:8242742, GO:0001569=GO_REF:0000019, GO:0043066=PMID:9884026, GO:0061445=PMID:19506109, GO:2000017=PMID:19506109, GO:0010862=PMID:19506109, GO:0045177=GO_REF:0000019, GO:0005524=PMID:12065756, GO:0045669=PMID:18436533, GO:0004674=PMID:12065756, GO:0004675=PMID:8242742, GO:0006468=PMID:19506109, GO:0017046=PMID:12702211} Q04771 Activin receptor type-1 protein 20120312 {GO:0005515=IPI, GO:0003289=IMP, GO:0001655=IEA, GO:0001755=IEA, GO:0003183=IMP, GO:0046332=IDA, GO:0007281=IEA, GO:0042803=IDA, GO:0007507=IEA, GO:0003143=IMP, GO:0004702=IEA, GO:0007179=IDA, GO:0009968=IMP, GO:0002526=IEA, GO:0001707=IEA, GO:0030501=IMP, GO:0032926=IMP, GO:0030509=IDA, GO:0032924=IDA, GO:0001701=IEA, GO:0060923=IMP, GO:0001702=IEA, GO:0060037=IEA, GO:0048641=IEA, GO:0071385=IEA, GO:0005887=IDA, GO:0048179=IDA, GO:0060389=IDA, GO:0045893=IDA, GO:0051145=IEA, GO:0016361=IDA, GO:0007368=IEA, GO:0046872=IEA, GO:0000082=IMP, GO:0030278=IMP, GO:0048185=IDA, GO:0045944=IDA, GO:0005025=IEA, GO:0050431=IDA, GO:0001569=IEA, GO:0043066=IMP, GO:0061445=IMP, GO:2000017=IDA, GO:0010862=IDA, GO:0045177=IEA, GO:0005524=IDA, GO:0045669=IMP, GO:0004674=IDA, GO:0004675=RCA, GO:0006468=IDA, GO:0017046=NAS} BMP signaling pathway, G1/S transition of mitotic cell cycle, activin receptor signaling pathway, acute inflammatory response, atrial septum primum morphogenesis, cardiac muscle cell fate commitment, cellular response to glucocorticoid stimulus, determination of left/right symmetry, embryonic heart tube morphogenesis, endocardial cushion cell fate commitment, gastrulation with mouth forming second, germ cell development, heart development, in utero embryonic development, mesoderm formation, mitral valve morphogenesis, negative regulation of activin receptor signaling pathway, negative regulation of apoptotic process, negative regulation of signal transduction, neural crest cell migration, pathway-restricted SMAD protein phosphorylation, patterning of blood vessels, pharyngeal system development, positive regulation of bone mineralization, positive regulation of determination of dorsal identity, positive regulation of osteoblast differentiation, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein phosphorylation, regulation of ossification, regulation of skeletal muscle tissue development, smooth muscle cell differentiation, transforming growth factor beta receptor signaling pathway, urogenital system development activin receptor complex, apical part of cell, integral to plasma membrane ATP binding, SMAD binding, activin binding, activin receptor activity, type I, metal ion binding, peptide hormone binding, protein binding, protein homodimerization activity, protein serine/threonine kinase activity, receptor signaling protein serine/threonine kinase activity, transforming growth factor beta binding, transforming growth factor beta receptor activity, type I, transmembrane receptor protein serine/threonine kinase activity Human ACVR1B BHF-UCL UniProtKB {GO:0005515=PMID:16720724, GO:0016361=PMID:8622651, GO:0030308=PMID:11117535, GO:0005886=Reactome:REACT_150345, GO:0046332=PMID:12065756, GO:0046872=GO_REF:0000037, GO:0000082=PMID:11117535, GO:0046777=PMID:18039968, GO:0019838=PMID:14517293, GO:0004702=GO_REF:0000019, GO:0048185=PMID:12665502, GO:0045944=GO_REF:0000019, GO:0018107=PMID:18039968, GO:0007178=PMID:8397373, GO:0005024=GO_REF:0000002, GO:0001942=GO_REF:0000019, GO:0031625=PMID:16720724, GO:1901165=PMID:21356369, GO:0046545=GO_REF:0000019, GO:0006355=PMID:8622651, GO:0009986=PMID:12665502, GO:0010862=GO_REF:0000019, GO:0032927=PMID:16720724, GO:0006917=PMID:9884026, GO:0007417=GO_REF:0000019, GO:0032924=PMID:9892009, GO:0001701=GO_REF:0000019, GO:0005524=PMID:12065756, GO:0007165=PMID:12665502, GO:0016020=GO_REF:0000002, GO:0045648=PMID:9032295, GO:0004674=Reactome:REACT_111058, GO:0005887=PMID:9032295, GO:0034711=PMID:7890768, GO:0004675=PMID:9032295, GO:0038092=PMID:11389842, GO:0006468=PMID:12065756, GO:0017002=PMID:12665502} P36896 Activin receptor type-1B protein 20120719 {GO:0005515=IPI, GO:0016361=TAS, GO:0030308=IDA, GO:0005886=TAS, GO:0046332=IDA, GO:0046872=IEA, GO:0000082=IDA, GO:0046777=IDA, GO:0019838=IPI, GO:0004702=IEA, GO:0048185=IDA, GO:0045944=IEA, GO:0018107=IDA, GO:0007178=TAS, GO:0005024=IEA, GO:0001942=IEA, GO:0031625=IPI, GO:1901165=IDA, GO:0046545=IEA, GO:0006355=IDA, GO:0009986=IDA, GO:0010862=IEA, GO:0032927=IDA, GO:0006917=IMP, GO:0007417=IEA, GO:0032924=IDA, GO:0001701=IEA, GO:0005524=IDA, GO:0007165=IDA, GO:0016020=IEA, GO:0045648=IDA, GO:0004674=EXP, GO:0005887=IDA, GO:0034711=IPI, GO:0004675=NAS, GO:0038092=IGI, GO:0006468=IDA, GO:0017002=IDA} G1/S transition of mitotic cell cycle, activin receptor signaling pathway, central nervous system development, development of primary female sexual characteristics, hair follicle development, in utero embryonic development, induction of apoptosis, negative regulation of cell growth, nodal signaling pathway, peptidyl-threonine phosphorylation, positive regulation of activin receptor signaling pathway, positive regulation of erythrocyte differentiation, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of trophoblast cell migration, protein autophosphorylation, protein phosphorylation, regulation of transcription, DNA-dependent, signal transduction, transmembrane receptor protein serine/threonine kinase signaling pathway cell surface, integral to plasma membrane, membrane, plasma membrane ATP binding, SMAD binding, activin binding, activin receptor activity, type I, activin-activated receptor activity, growth factor binding, inhibin binding, metal ion binding, protein binding, protein serine/threonine kinase activity, receptor signaling protein serine/threonine kinase activity, transforming growth factor beta-activated receptor activity, transmembrane receptor protein serine/threonine kinase activity, ubiquitin protein ligase binding Human ACVR1C BHF-UCL UniProtKB {GO:0016361=PMID:12063393, GO:0032868=GO_REF:0000019, GO:0005886=Reactome:REACT_150345, GO:0019915=GO_REF:0000019, GO:0042981=PMID:15531507, GO:1901383=PMID:15150278, GO:0005524=GO_REF:0000037, GO:0002021=GO_REF:0000019, GO:0046872=PMID:12063393, GO:0030154=PMID:15531507, GO:0009749=GO_REF:0000019, GO:0048179=PMID:15531507, GO:0038092=PMID:15150278, GO:0005024=GO_REF:0000002, GO:0038100=PMID:21356369, GO:0006468=PMID:12063393, GO:0046676=GO_REF:0000019} Q8NER5 Activin receptor type-1C protein 20120517 {GO:0016361=IDA, GO:0032868=IEA, GO:0005886=TAS, GO:0019915=IEA, GO:0042981=IDA, GO:1901383=IMP, GO:0005524=IEA, GO:0002021=IEA, GO:0046872=IC, GO:0030154=IDA, GO:0009749=IEA, GO:0048179=IDA, GO:0038092=IMP, GO:0005024=IEA, GO:0038100=IMP, GO:0006468=IC, GO:0046676=IEA} cell differentiation, lipid storage, negative regulation of chorionic trophoblast cell proliferation, negative regulation of insulin secretion, nodal signaling pathway, protein phosphorylation, regulation of apoptotic process, response to dietary excess, response to glucose stimulus, response to insulin stimulus activin receptor complex, plasma membrane ATP binding, activin receptor activity, type I, metal ion binding, nodal binding, transforming growth factor beta-activated receptor activity Human ACVR2A BHF-UCL UniProtKB {GO:0005515=PMID:10746731, GO:0007368=GO_REF:0000019, GO:0005886=Reactome:REACT_150345, GO:0050999=GO_REF:0000019, GO:0048706=GO_REF:0000019, GO:0034673=PMID:10746731, GO:0007283=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0043621=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005737=PMID:14738881, GO:0004702=GO_REF:0000002, GO:0019838=GO_REF:0000019, GO:0048185=PMID:9032295, GO:0007178=PMID:1314589, GO:0005024=GO_REF:0000002, GO:0030510=GO_REF:0000019, GO:0030501=PMID:18436533, GO:0009986=GO_REF:0000019, GO:0032927=PMID:12665502, GO:0030509=PMID:19366699, GO:0043084=GO_REF:0000019, GO:0015026=PMID:10746731, GO:0030165=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0001702=GO_REF:0000019, GO:0042713=GO_REF:0000019, GO:0045669=PMID:18436533, GO:0016020=GO_REF:0000002, GO:0004674=Reactome:REACT_111068, GO:0045648=PMID:9032295, GO:0005887=PMID:1314589, GO:0004675=PMID:1314589, GO:0034711=GO_REF:0000019, GO:0001934=PMID:17472960, GO:0007498=GO_REF:0000019, GO:0017002=PMID:12665502, GO:0060011=GO_REF:0000019} P27037 Activin receptor type-2A protein 20120314 {GO:0005515=IPI, GO:0007368=IEA, GO:0005886=TAS, GO:0050999=IEA, GO:0048706=IEA, GO:0034673=IDA, GO:0007283=IEA, GO:0009952=IEA, GO:0043621=IEA, GO:0046872=IEA, GO:0005737=IDA, GO:0004702=IEA, GO:0019838=IEA, GO:0048185=IPI, GO:0007178=TAS, GO:0005024=IEA, GO:0030510=IEA, GO:0030501=IMP, GO:0009986=IEA, GO:0032927=IDA, GO:0030509=IMP, GO:0043084=IEA, GO:0015026=IDA, GO:0030165=IEA, GO:0005524=IEA, GO:0001702=IEA, GO:0042713=IEA, GO:0045669=IMP, GO:0016020=IEA, GO:0004674=EXP, GO:0045648=IDA, GO:0005887=TAS, GO:0004675=TAS, GO:0034711=IEA, GO:0001934=IMP, GO:0007498=IEA, GO:0017002=IDA, GO:0060011=IEA} BMP signaling pathway, Sertoli cell proliferation, anterior/posterior pattern specification, determination of left/right symmetry, embryonic skeletal system development, gastrulation with mouth forming second, mesoderm development, penile erection, positive regulation of activin receptor signaling pathway, positive regulation of bone mineralization, positive regulation of erythrocyte differentiation, positive regulation of osteoblast differentiation, positive regulation of protein phosphorylation, regulation of BMP signaling pathway, regulation of nitric-oxide synthase activity, sperm ejaculation, spermatogenesis, transmembrane receptor protein serine/threonine kinase signaling pathway cell surface, cytoplasm, inhibin-betaglycan-ActRII complex, integral to plasma membrane, membrane, plasma membrane ATP binding, PDZ domain binding, activin binding, activin-activated receptor activity, coreceptor activity, growth factor binding, inhibin binding, metal ion binding, protein binding, protein self-association, protein serine/threonine kinase activity, receptor signaling protein serine/threonine kinase activity, transforming growth factor beta-activated receptor activity, transmembrane receptor protein serine/threonine kinase activity Human ACVR2B BHF-UCL UniProtKB {GO:0005515=PMID:9872992, GO:0007368=GO_REF:0000019, GO:0005886=Reactome:REACT_150345, GO:0030324=GO_REF:0000019, GO:0061298=GO_REF:0000024, GO:0048705=GO_REF:0000019, GO:0009952=PMID:9916847, GO:0009791=GO_REF:0000019, GO:0060836=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0016362=PMID:8622651, GO:0007507=GO_REF:0000019, GO:0032147=GO_REF:0000019, GO:0001946=GO_REF:0000024, GO:0005737=PMID:14738881, GO:0019838=PMID:14517293, GO:0004702=GO_REF:0000002, GO:0035265=GO_REF:0000019, GO:0048185=GO_REF:0000019, GO:0007178=PMID:8161782, GO:0005024=GO_REF:0000002, GO:0042475=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:0006355=PMID:8622651, GO:0030501=PMID:18436533, GO:0009986=PMID:12493773, GO:0001822=GO_REF:0000019, GO:0030509=PMID:19903896, GO:0032927=PMID:8622651, GO:0005524=GO_REF:0000037, GO:0001702=GO_REF:0000019, GO:0009749=GO_REF:0000019, GO:0045669=PMID:18436533, GO:0007165=PMID:8622651, GO:0031016=GO_REF:0000019, GO:0004674=Reactome:REACT_111068, GO:0005887=PMID:8161782, GO:0034711=GO_REF:0000019, GO:0048617=GO_REF:0000019, GO:0007498=GO_REF:0000019, GO:0004712=GO_REF:0000019, GO:0030073=GO_REF:0000019} Q13705 Activin receptor type-2B protein 20120319 {GO:0005515=IPI, GO:0007368=IEA, GO:0005886=TAS, GO:0030324=IEA, GO:0061298=ISS, GO:0048705=IEA, GO:0009952=IMP, GO:0009791=IEA, GO:0060836=ISS, GO:0046872=IEA, GO:0016362=TAS, GO:0007507=IEA, GO:0032147=IEA, GO:0001946=ISS, GO:0005737=IDA, GO:0019838=IPI, GO:0004702=IEA, GO:0035265=IEA, GO:0048185=IEA, GO:0007178=TAS, GO:0005024=IEA, GO:0042475=IEA, GO:0060021=IEA, GO:0006355=IDA, GO:0030501=IMP, GO:0009986=IDA, GO:0001822=IEA, GO:0030509=IMP, GO:0032927=IDA, GO:0005524=IEA, GO:0001702=IEA, GO:0009749=IEA, GO:0045669=IMP, GO:0007165=IDA, GO:0031016=IEA, GO:0004674=EXP, GO:0005887=TAS, GO:0034711=IEA, GO:0048617=IEA, GO:0007498=IEA, GO:0004712=IEA, GO:0030073=IEA} BMP signaling pathway, activation of protein kinase activity, anterior/posterior pattern specification, determination of left/right symmetry, embryonic foregut morphogenesis, gastrulation with mouth forming second, heart development, insulin secretion, kidney development, lung development, lymphangiogenesis, lymphatic endothelial cell differentiation, mesoderm development, odontogenesis of dentin-containing tooth, organ growth, palate development, pancreas development, positive regulation of activin receptor signaling pathway, positive regulation of bone mineralization, positive regulation of osteoblast differentiation, post-embryonic development, regulation of transcription, DNA-dependent, response to glucose stimulus, retina vasculature development in camera-type eye, signal transduction, skeletal system morphogenesis, transmembrane receptor protein serine/threonine kinase signaling pathway cell surface, cytoplasm, integral to plasma membrane, plasma membrane ATP binding, activin binding, activin receptor activity, type II, growth factor binding, inhibin binding, metal ion binding, protein binding, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity, receptor signaling protein serine/threonine kinase activity, transforming growth factor beta-activated receptor activity Human UniProtKB:P27040 ACVRL1 BHF-UCL UniProtKB {GO:0005515=PMID:18974388, GO:0030308=PMID:17068149, GO:0008015=PMID:16752392, GO:0046332=PMID:12065756, GO:0001946=GO_REF:0000024, GO:0004702=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0007179=PMID:15702480, GO:0030336=PMID:12453878, GO:0009986=PMID:8242742, GO:0030509=PMID:19366699, GO:0001701=GO_REF:0000019, GO:0043535=PMID:20406889, GO:0010596=PMID:17068149, GO:0061154=PMID:19592636, GO:0005887=PMID:8242742, GO:0045893=PMID:12393874, GO:0045603=GO_REF:0000019, GO:0001955=PMID:20406889, GO:0043537=PMID:19592636, GO:0045602=GO_REF:0000019, GO:0016361=PMID:8242742, GO:0008285=PMID:12453878, GO:0035313=PMID:12453878, GO:0061298=GO_REF:0000024, GO:0002043=PMID:20406889, GO:0051291=GO_REF:0000019, GO:0060836=PMID:19903896, GO:0030425=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0051895=PMID:12453878, GO:0030513=PMID:17068149, GO:0048185=PMID:8242742, GO:0005024=PMID:8242742, GO:0032332=PMID:19494318, GO:0005025=PMID:8242742, GO:0006275=PMID:20406889, GO:0050431=PMID:8242742, GO:0006355=PMID:15702480, GO:0060841=GO_REF:0000019, GO:0060840=GO_REF:0000019, GO:0001525=PMID:16752392, GO:0005524=PMID:12065756, GO:0007165=PMID:15702480, GO:0007162=PMID:12453878, GO:0004672=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0001938=GO_REF:0000019, GO:0001974=GO_REF:0000019, GO:0004674=PMID:12065756, GO:0001937=GO_REF:0000019, GO:0004675=PMID:8242742, GO:0001936=PMID:20406889, GO:0008217=PMID:14684682, GO:0006468=PMID:12065756} P37023 Serine/threonine-protein kinase receptor R3 protein 20120314 {GO:0005515=IPI, GO:0030308=IDA, GO:0008015=IMP, GO:0046332=IDA, GO:0001946=ISS, GO:0004702=IEA, GO:0043025=IEA, GO:0007179=IDA, GO:0030336=IMP, GO:0009986=IDA, GO:0030509=IMP, GO:0001701=IEA, GO:0043535=TAS, GO:0010596=IDA, GO:0061154=IMP, GO:0005887=IDA, GO:0045893=IDA, GO:0045603=IEA, GO:0001955=TAS, GO:0043537=IMP, GO:0045602=IEA, GO:0016361=IDA, GO:0008285=IMP, GO:0035313=IMP, GO:0061298=ISS, GO:0002043=TAS, GO:0051291=IEA, GO:0060836=IMP, GO:0030425=IEA, GO:0046872=IEA, GO:0051895=IMP, GO:0030513=IDA, GO:0048185=IDA, GO:0005024=IDA, GO:0032332=TAS, GO:0005025=IDA, GO:0006275=TAS, GO:0050431=IPI, GO:0006355=IMP, GO:0060841=IEA, GO:0060840=IEA, GO:0001525=IMP, GO:0005524=IDA, GO:0007165=IDA, GO:0007162=IMP, GO:0004672=IEA, GO:0016020=IEA, GO:0001938=IEA, GO:0001974=IEA, GO:0004674=IDA, GO:0001937=IEA, GO:0004675=RCA, GO:0001936=TAS, GO:0008217=IMP, GO:0006468=IDA} BMP signaling pathway, angiogenesis, artery development, blood circulation, blood vessel endothelial cell proliferation involved in sprouting angiogenesis, blood vessel maturation, blood vessel remodeling, endothelial tube morphogenesis, in utero embryonic development, lymphangiogenesis, lymphatic endothelial cell differentiation, negative regulation of blood vessel endothelial cell migration, negative regulation of cell adhesion, negative regulation of cell growth, negative regulation of cell migration, negative regulation of cell proliferation, negative regulation of endothelial cell differentiation, negative regulation of endothelial cell migration, negative regulation of endothelial cell proliferation, negative regulation of focal adhesion assembly, positive regulation of BMP signaling pathway, positive regulation of chondrocyte differentiation, positive regulation of endothelial cell differentiation, positive regulation of endothelial cell proliferation, positive regulation of transcription, DNA-dependent, protein heterooligomerization, protein phosphorylation, regulation of DNA replication, regulation of blood pressure, regulation of blood vessel endothelial cell migration, regulation of endothelial cell proliferation, regulation of transcription, DNA-dependent, retina vasculature development in camera-type eye, signal transduction, transforming growth factor beta receptor signaling pathway, venous blood vessel development, wound healing, spreading of epidermal cells cell surface, dendrite, integral to plasma membrane, membrane, neuronal cell body ATP binding, SMAD binding, activin binding, activin receptor activity, type I, metal ion binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, receptor signaling protein serine/threonine kinase activity, transforming growth factor beta binding, transforming growth factor beta receptor activity, type I, transforming growth factor beta-activated receptor activity, transmembrane receptor protein serine/threonine kinase activity Human ACY1 PINC UniProtKB {GO:0006520=GO_REF:0000002, GO:0005737=GO_REF:0000002, GO:0006508=GO_REF:0000002, GO:0004046=GO_REF:0000003, GO:0046872=GO_REF:0000037, GO:0008237=GO_REF:0000002, GO:0005829=PMID:8394326} Q03154 Aminoacylase-1 protein 20030904 {GO:0006520=IEA, GO:0005737=IEA, GO:0006508=IEA, GO:0004046=IEA, GO:0046872=IEA, GO:0008237=IEA, GO:0005829=TAS} cellular amino acid metabolic process, proteolysis cytoplasm, cytosol aminoacylase activity, metal ion binding, metallopeptidase activity Human ACY3 UniProtKB UniProtKB {GO:0016324=GO_REF:0000039, GO:0005737=GO_REF:0000039, GO:0019048=GO_REF:0000037, GO:0016788=GO_REF:0000002, GO:0004046=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0042802=GO_REF:0000019} Q96HD9 Aspartoacylase-2 protein 20130413 {GO:0016324=IEA, GO:0005737=IEA, GO:0019048=IEA, GO:0016788=IEA, GO:0004046=IEA, GO:0046872=IEA, GO:0042802=IEA} virus-host interaction apical plasma membrane, cytoplasm aminoacylase activity, hydrolase activity, acting on ester bonds, identical protein binding, metal ion binding Human UniProtKB-SubCell:SL-0015 ACYP1 PINC UniProtKB {GO:0003998=GO_REF:0000003, GO:0006796=PMID:3026468} P07311 Acylphosphatase-1 protein 20030904 {GO:0003998=IEA, GO:0006796=TAS} phosphate-containing compound metabolic process acylphosphatase activity Human ACYP2 PINC UniProtKB {GO:0005739=GO_REF:0000019, GO:0003998=GO_REF:0000003, GO:0006796=PMID:8268218} P14621 Acylphosphatase-2 protein 20030904 {GO:0005739=IEA, GO:0003998=IEA, GO:0006796=TAS} phosphate-containing compound metabolic process mitochondrion acylphosphatase activity Human ADA HPA UniProtKB {GO:0046638=GO_REF:0000019, GO:0005515=PMID:8101391, GO:0042542=GO_REF:0000019, GO:0033089=GO_REF:0000019, GO:0046061=GO_REF:0000019, GO:0030054=GO_REF:0000039, GO:0060407=GO_REF:0000019, GO:0060205=GO_REF:0000039, GO:0005764=PMID:8452534, GO:0005615=GO_REF:0000019, GO:0048541=GO_REF:0000019, GO:0002906=GO_REF:0000019, GO:0032261=PMID:9361033, GO:0006157=GO_REF:0000019, GO:0006154=PMID:8894685, GO:0043025=GO_REF:0000019, GO:0048286=GO_REF:0000019, GO:0009986=PMID:11772392, GO:0007568=GO_REF:0000019, GO:0070244=GO_REF:0000019, GO:0043278=GO_REF:0000019, GO:0001890=GO_REF:0000019, GO:0001889=GO_REF:0000019, GO:0042110=PMID:7594462, GO:0006144=Reactome:REACT_522, GO:0001883=GO_REF:0000019, GO:0008270=GO_REF:0000024, GO:0010460=GO_REF:0000019, GO:0009897=PMID:16670267, GO:0002314=GO_REF:0000019, GO:0009168=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0030890=GO_REF:0000019, GO:0046103=PMID:8894685, GO:0032839=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0070256=GO_REF:0000019, GO:0005829=Reactome:REACT_2135, GO:0050850=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0046111=GO_REF:0000019, GO:0004000=PMID:8894685, GO:0060169=PMID:16670267, GO:0045987=GO_REF:0000019, GO:0043101=Reactome:REACT_1923, GO:0002636=GO_REF:0000019, GO:0043103=GO_REF:0000033, GO:0007155=GO_REF:0000037, GO:0001666=PMID:16670267, GO:0001821=GO_REF:0000019, GO:0019239=GO_REF:0000002, GO:0055086=Reactome:REACT_1698, GO:0033632=PMID:11772392, GO:0048566=GO_REF:0000019, GO:0001829=GO_REF:0000019, GO:0050862=GO_REF:0000019, GO:0042323=GO_REF:0000019, GO:0016020=PMID:11999881, GO:0002686=GO_REF:0000019, GO:0050728=GO_REF:0000019} P00813 Adenosine deaminase protein 20101115 {GO:0046638=IEA, GO:0005515=IPI, GO:0042542=IEA, GO:0033089=IEA, GO:0046061=IEA, GO:0030054=IEA, GO:0060407=IEA, GO:0060205=IEA, GO:0005764=IDA, GO:0005615=IEA, GO:0048541=IEA, GO:0002906=IEA, GO:0032261=IMP, GO:0006157=IEA, GO:0006154=IDA, GO:0043025=IEA, GO:0048286=IEA, GO:0009986=IDA, GO:0007568=IEA, GO:0070244=IEA, GO:0043278=IEA, GO:0001890=IEA, GO:0001889=IEA, GO:0042110=IDA, GO:0006144=TAS, GO:0001883=IEA, GO:0008270=ISS, GO:0010460=IEA, GO:0009897=IDA, GO:0002314=IEA, GO:0009168=IEA, GO:0005886=IDA, GO:0030890=IEA, GO:0046103=IDA, GO:0032839=IEA, GO:0044281=TAS, GO:0070256=IEA, GO:0005829=TAS, GO:0050850=IEA, GO:0005737=IDA, GO:0046111=IEA, GO:0004000=IDA, GO:0060169=IDA, GO:0045987=IEA, GO:0043101=TAS, GO:0002636=IEA, GO:0043103=IBA, GO:0007155=IEA, GO:0001666=IDA, GO:0001821=IEA, GO:0019239=IEA, GO:0055086=TAS, GO:0033632=IDA, GO:0048566=IEA, GO:0001829=IEA, GO:0050862=IEA, GO:0042323=IEA, GO:0016020=IDA, GO:0002686=IEA, GO:0050728=IEA} Peyer's patch development, T cell activation, adenosine catabolic process, aging, cell adhesion, dATP catabolic process, deoxyadenosine catabolic process, embryonic digestive tract development, germinal center B cell differentiation, histamine secretion, hypoxanthine salvage, inosine biosynthetic process, liver development, lung alveolus development, negative regulation of adenosine receptor signaling pathway, negative regulation of circadian sleep/wake cycle, non-REM sleep, negative regulation of inflammatory response, negative regulation of leukocyte migration, negative regulation of mature B cell apoptotic process, negative regulation of mucus secretion, negative regulation of penile erection, negative regulation of thymocyte apoptotic process, nucleobase-containing small molecule metabolic process, placenta development, positive regulation of B cell proliferation, positive regulation of T cell differentiation in thymus, positive regulation of T cell receptor signaling pathway, positive regulation of alpha-beta T cell differentiation, positive regulation of calcium-mediated signaling, positive regulation of germinal center formation, positive regulation of heart rate, positive regulation of smooth muscle contraction, purine nucleobase metabolic process, purine nucleotide salvage, purine ribonucleoside monophosphate biosynthetic process, purine-containing compound salvage, regulation of cell-cell adhesion mediated by integrin, response to hydrogen peroxide, response to hypoxia, response to morphine, small molecule metabolic process, trophectodermal cell differentiation, xanthine biosynthetic process cell junction, cell surface, cytoplasm, cytoplasmic membrane-bounded vesicle lumen, cytosol, dendrite cytoplasm, external side of plasma membrane, extracellular space, lysosome, membrane, neuronal cell body, plasma membrane adenosine deaminase activity, deaminase activity, protein binding, purine nucleoside binding, zinc ion binding Human ADAD2 InterPro UniProtKB {GO:0003725=GO_REF:0000002, GO:0006396=GO_REF:0000002, GO:0004000=GO_REF:0000002} Q8NCV1 Adenosine deaminase domain-containing protein 2 protein 20130413 {GO:0003725=IEA, GO:0006396=IEA, GO:0004000=IEA} RNA processing adenosine deaminase activity, double-stranded RNA binding Human InterPro:IPR002466 ADAM10 BHF-UCL UniProtKB {GO:0005515=PMID:10527948, GO:0008284=PMID:18373975, GO:0017124=GO_REF:0000037, GO:0007220=Reactome:REACT_2001, GO:0005886=Reactome:REACT_160218, GO:0030307=PMID:18373975, GO:0007267=PMID:12714508, GO:0005634=GO_REF:0000024, GO:0051089=PMID:12714508, GO:0051088=PMID:18676862, GO:0042803=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0022617=Reactome:REACT_118572, GO:0007173=Reactome:REACT_9417, GO:0007219=Reactome:REACT_118862, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0006509=PMID:19114711, GO:0030335=PMID:18373975, GO:0005794=PMID:12475894, GO:0019901=GO_REF:0000024, GO:0009986=PMID:12475894, GO:0010820=PMID:18373975, GO:0005798=PMID:12475894, GO:0005102=PMID:12176995, GO:0014069=GO_REF:0000019, GO:0001701=GO_REF:0000024, GO:0012505=GO_REF:0000039, GO:0007162=PMID:12714508, GO:0005178=PMID:8694785, GO:0004175=GO_REF:0000024, GO:0042117=PMID:11831872, GO:0007229=PMID:8694785, GO:0034612=PMID:11831872, GO:0006468=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0016021=PMID:8694785, GO:0004222=PMID:19114711, GO:0008237=PMID:12535668} O14672 Disintegrin and metalloproteinase domain-containing protein 10 protein 20101126 {GO:0005515=IPI, GO:0008284=IMP, GO:0017124=IEA, GO:0007220=TAS, GO:0005886=TAS, GO:0030307=IMP, GO:0007267=NAS, GO:0005634=ISS, GO:0051089=IDA, GO:0051088=IMP, GO:0042803=ISS, GO:0005737=ISS, GO:0022617=TAS, GO:0007173=TAS, GO:0007219=TAS, GO:0030198=TAS, GO:0030574=TAS, GO:0006509=IDA, GO:0030335=IMP, GO:0005794=IDA, GO:0019901=ISS, GO:0009986=IDA, GO:0010820=IMP, GO:0005798=IDA, GO:0005102=NAS, GO:0014069=IEA, GO:0001701=ISS, GO:0012505=IEA, GO:0007162=IDA, GO:0005178=NAS, GO:0004175=ISS, GO:0042117=IMP, GO:0007229=NAS, GO:0034612=IDA, GO:0006468=ISS, GO:0008270=IEA, GO:0016021=NAS, GO:0004222=IMP, GO:0008237=IMP} Notch receptor processing, Notch signaling pathway, PMA-inducible membrane protein ectodomain proteolysis, cell-cell signaling, collagen catabolic process, constitutive protein ectodomain proteolysis, epidermal growth factor receptor signaling pathway, extracellular matrix disassembly, extracellular matrix organization, in utero embryonic development, integrin-mediated signaling pathway, membrane protein ectodomain proteolysis, monocyte activation, negative regulation of cell adhesion, positive regulation of T cell chemotaxis, positive regulation of cell growth, positive regulation of cell migration, positive regulation of cell proliferation, protein phosphorylation, response to tumor necrosis factor Golgi apparatus, Golgi-associated vesicle, cell surface, cytoplasm, endomembrane system, integral to membrane, nucleus, plasma membrane, postsynaptic density SH3 domain binding, endopeptidase activity, integrin binding, metalloendopeptidase activity, metallopeptidase activity, protein binding, protein homodimerization activity, protein kinase binding, receptor binding, zinc ion binding Human UniProtKB:Q9UI95 ADAM11 BHF-UCL UniProtKB {GO:0031012=PMID:22261194, GO:0005178=PMID:9693107, GO:0005886=PMID:9693107, GO:0007229=PMID:8252040, GO:0006508=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0004222=GO_REF:0000002, GO:0008237=PMID:9693107} O75078 Disintegrin and metalloproteinase domain-containing protein 11 protein 20120228 {GO:0031012=ISS, GO:0005178=TAS, GO:0005886=TAS, GO:0007229=TAS, GO:0006508=IEA, GO:0008270=IEA, GO:0016021=IEA, GO:0004222=IEA, GO:0008237=TAS} integrin-mediated signaling pathway, proteolysis extracellular matrix, integral to membrane, plasma membrane integrin binding, metalloendopeptidase activity, metallopeptidase activity, zinc ion binding colocalizes_with Human UniProtKB:F1RQZ7 ADAM12 UniProtKB UniProtKB {GO:0017124=PMID:15280379, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005576=GO_REF:0000038, GO:0007520=PMID:7566181, GO:0005634=GO_REF:0000052, GO:0005739=GO_REF:0000052, GO:0007173=Reactome:REACT_9417, GO:0006508=GO_REF:0000038, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0004222=GO_REF:0000002, GO:0007155=GO_REF:0000037, GO:0008237=PMID:9417060} Q5JRP2 Disintegrin and metalloproteinase domain-containing protein 12 protein 20130413 {GO:0017124=IPI, GO:0005886=IDA, GO:0005730=IDA, GO:0005576=IEA, GO:0007520=TAS, GO:0005634=IDA, GO:0005739=IDA, GO:0007173=TAS, GO:0006508=IEA, GO:0008270=IEA, GO:0016021=IEA, GO:0004222=IEA, GO:0007155=IEA, GO:0008237=TAS} cell adhesion, epidermal growth factor receptor signaling pathway, myoblast fusion, proteolysis extracellular region, integral to membrane, mitochondrion, nucleolus, nucleus, plasma membrane SH3 domain binding, metalloendopeptidase activity, metallopeptidase activity, zinc ion binding Human UniProtKB-KW:KW-0645 ADAM15 BHF-UCL UniProtKB {GO:0005515=PMID:15280379, GO:0017124=PMID:10531379, GO:0001669=GO_REF:0000039, GO:0001525=GO_REF:0000037, GO:0042995=GO_REF:0000037, GO:0042246=GO_REF:0000019, GO:0012505=GO_REF:0000039, GO:0060317=GO_REF:0000019, GO:0005912=GO_REF:0000039, GO:0007160=PMID:9516430, GO:0030574=GO_REF:0000037, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0004222=GO_REF:0000002, GO:0008237=PMID:12777399} Q13444 Disintegrin and metalloproteinase domain-containing protein 15 protein 20110220 {GO:0005515=IPI, GO:0017124=IPI, GO:0001669=IEA, GO:0001525=IEA, GO:0042995=IEA, GO:0042246=IEA, GO:0012505=IEA, GO:0060317=IEA, GO:0005912=IEA, GO:0007160=TAS, GO:0030574=IEA, GO:0006508=IEA, GO:0008270=IEA, GO:0016021=IEA, GO:0004222=IEA, GO:0008237=IDA} angiogenesis, cardiac epithelial to mesenchymal transition, cell-matrix adhesion, collagen catabolic process, proteolysis, tissue regeneration acrosomal vesicle, adherens junction, cell projection, endomembrane system, integral to membrane SH3 domain binding, metalloendopeptidase activity, metallopeptidase activity, protein binding, zinc ion binding Human ADAM17 BHF-UCL UniProtKB {GO:0005515=PMID:10527948, GO:0032717=PMID:16034137, GO:0033025=PMID:10433800, GO:0030307=PMID:18373975, GO:0048536=PMID:10433800, GO:0007219=GO_REF:0000037, GO:0007173=PMID:12743035, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0006508=GO_REF:0000002, GO:0032496=PMID:18383040, GO:0006509=PMID:18676862, GO:0002467=PMID:10433800, GO:0033077=PMID:10433800, GO:0030335=PMID:18373975, GO:0009986=PMID:18625725, GO:0035625=PMID:17655843, GO:0045741=PMID:18483258, GO:0032722=PMID:16034137, GO:0030165=PMID:12207026, GO:0055099=PMID:17786981, GO:0005178=PMID:14970227, GO:0005887=PMID:17786981, GO:0045121=PMID:17010968, GO:0008270=GO_REF:0000002, GO:0004222=PMID:9920899, GO:0005925=PMID:14970227, GO:0008237=PMID:12777399, GO:0005138=PMID:16034137, GO:0008284=PMID:18373975, GO:0017124=GO_REF:0000037, GO:0033627=PMID:14970227, GO:0035313=PMID:14970227, GO:0005886=Reactome:REACT_150205, GO:0031293=Reactome:REACT_13443, GO:0060397=Reactome:REACT_111133, GO:0051088=PMID:18676862, GO:0015629=PMID:17010968, GO:0005737=GO_REF:0000019, GO:0016324=PMID:16034137, GO:0022617=Reactome:REACT_118572, GO:0005911=PMID:14970227, GO:0048870=PMID:10433800, GO:0030183=PMID:10433800, GO:0007155=PMID:14970227, GO:0030511=PMID:10433800, GO:0001666=PMID:18276953, GO:0048011=Reactome:REACT_13776, GO:0002446=PMID:16034137, GO:0042493=PMID:10433800, GO:0010820=PMID:18373975, GO:0032587=PMID:14970227, GO:0002690=PMID:16034137, GO:0031659=PMID:18483258, GO:0001934=PMID:18625725, GO:0051272=PMID:10433800} P78536 Disintegrin and metalloproteinase domain-containing protein 17 protein 20110110 {GO:0005515=IPI, GO:0032717=IMP, GO:0033025=ISS, GO:0030307=IMP, GO:0048536=ISS, GO:0007219=IEA, GO:0007173=IDA, GO:0030198=TAS, GO:0030574=TAS, GO:0006508=IEA, GO:0032496=IDA, GO:0006509=IDA, GO:0002467=ISS, GO:0033077=ISS, GO:0030335=IMP, GO:0009986=IDA, GO:0035625=IMP, GO:0045741=IDA, GO:0032722=IMP, GO:0030165=IPI, GO:0055099=IDA, GO:0005178=IPI, GO:0005887=IDA, GO:0045121=IDA, GO:0008270=IEA, GO:0004222=IDA, GO:0005925=IDA, GO:0008237=IDA, GO:0005138=IPI, GO:0008284=IMP, GO:0017124=IEA, GO:0033627=IDA, GO:0035313=IEP, GO:0005886=TAS, GO:0031293=TAS, GO:0060397=TAS, GO:0051088=IMP, GO:0015629=IDA, GO:0005737=IEA, GO:0016324=IDA, GO:0022617=TAS, GO:0005911=IDA, GO:0048870=ISS, GO:0030183=ISS, GO:0007155=IDA, GO:0030511=ISS, GO:0001666=IDA, GO:0048011=TAS, GO:0002446=IC, GO:0042493=ISS, GO:0010820=IMP, GO:0032587=IDA, GO:0002690=IC, GO:0031659=IDA, GO:0001934=IMP, GO:0051272=ISS} B cell differentiation, JAK-STAT cascade involved in growth hormone signaling pathway, Notch signaling pathway, PMA-inducible membrane protein ectodomain proteolysis, T cell differentiation in thymus, cell adhesion, cell adhesion mediated by integrin, cell motility, collagen catabolic process, epidermal growth factor receptor signaling pathway, epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway, extracellular matrix disassembly, extracellular matrix organization, germinal center formation, membrane protein ectodomain proteolysis, membrane protein intracellular domain proteolysis, negative regulation of interleukin-8 production, neurotrophin TRK receptor signaling pathway, neutrophil mediated immunity, positive regulation of T cell chemotaxis, positive regulation of cell growth, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of cellular component movement, positive regulation of chemokine production, positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S, positive regulation of epidermal growth factor-activated receptor activity, positive regulation of leukocyte chemotaxis, positive regulation of protein phosphorylation, positive regulation of transforming growth factor beta receptor signaling pathway, proteolysis, regulation of mast cell apoptotic process, response to drug, response to high density lipoprotein particle stimulus, response to hypoxia, response to lipopolysaccharide, spleen development, wound healing, spreading of epidermal cells actin cytoskeleton, apical plasma membrane, cell surface, cell-cell junction, cytoplasm, focal adhesion, integral to plasma membrane, membrane raft, plasma membrane, ruffle membrane PDZ domain binding, SH3 domain binding, integrin binding, interleukin-6 receptor binding, metalloendopeptidase activity, metallopeptidase activity, protein binding, zinc ion binding Human ADAM19 ENSEMBL UniProtKB {GO:0007507=GO_REF:0000019, GO:0017124=GO_REF:0000037, GO:0006508=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0006509=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0004222=GO_REF:0000002} Q9H013 Disintegrin and metalloproteinase domain-containing protein 19 protein 20130413 {GO:0007507=IEA, GO:0017124=IEA, GO:0006508=IEA, GO:0008270=IEA, GO:0006509=IEA, GO:0016021=IEA, GO:0004222=IEA} heart development, membrane protein ectodomain proteolysis, proteolysis integral to membrane SH3 domain binding, metalloendopeptidase activity, zinc ion binding Human Ensembl:ENSMUSP00000011400 ADAM2 PINC UniProtKB {GO:0005178=PMID:9041139, GO:0007342=PMID:9041139, GO:0005887=PMID:9041139, GO:0007229=GO_REF:0000038, GO:0008542=GO_REF:0000019, GO:0006508=GO_REF:0000002, GO:0030534=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0007155=GO_REF:0000019, GO:0004222=GO_REF:0000002, GO:0008237=PMID:9041139} Q99965 Disintegrin and metalloproteinase domain-containing protein 2 protein 20030904 {GO:0005178=TAS, GO:0007342=TAS, GO:0005887=TAS, GO:0007229=IEA, GO:0008542=IEA, GO:0006508=IEA, GO:0030534=IEA, GO:0008270=IEA, GO:0007155=IEA, GO:0004222=IEA, GO:0008237=TAS} adult behavior, cell adhesion, fusion of sperm to egg plasma membrane, integrin-mediated signaling pathway, proteolysis, visual learning integral to plasma membrane integrin binding, metalloendopeptidase activity, metallopeptidase activity, zinc ion binding Human ADAM20 PINC UniProtKB {GO:0007338=PMID:9469942, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0004222=GO_REF:0000002, GO:0008237=PMID:9469942} O43506 Disintegrin and metalloproteinase domain-containing protein 20 protein 20030904 {GO:0007338=TAS, GO:0006508=IEA, GO:0008270=IEA, GO:0016021=IEA, GO:0004222=IEA, GO:0008237=TAS} proteolysis, single fertilization integral to membrane metalloendopeptidase activity, metallopeptidase activity, zinc ion binding Human ADAM22 PINC UniProtKB {GO:0005515=PMID:20463223, GO:0008344=GO_REF:0000019, GO:0007162=PMID:9693107, GO:0005178=PMID:9693107, GO:0022011=GO_REF:0000019, GO:0006508=GO_REF:0000002, GO:0005576=GO_REF:0000038, GO:0008270=GO_REF:0000002, GO:0016021=PMID:9693107, GO:0007417=PMID:9693107, GO:0007155=GO_REF:0000037, GO:0004222=GO_REF:0000002} Q9P0K1 Disintegrin and metalloproteinase domain-containing protein 22 protein 20050308 {GO:0005515=IPI, GO:0008344=IEA, GO:0007162=NAS, GO:0005178=NAS, GO:0022011=IEA, GO:0006508=IEA, GO:0005576=IEA, GO:0008270=IEA, GO:0016021=NAS, GO:0007417=TAS, GO:0007155=IEA, GO:0004222=IEA} adult locomotory behavior, cell adhesion, central nervous system development, myelination in peripheral nervous system, negative regulation of cell adhesion, proteolysis extracellular region, integral to membrane integrin binding, metalloendopeptidase activity, protein binding, zinc ion binding Human ADAM23 PINC UniProtKB {GO:0005515=PMID:20463223, GO:0005178=PMID:9693107, GO:0005887=PMID:9693107, GO:0006508=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0007417=PMID:9693107, GO:0007155=GO_REF:0000037, GO:0004222=GO_REF:0000002, GO:0008237=PMID:9693107} O75077 Disintegrin and metalloproteinase domain-containing protein 23 protein 20030904 {GO:0005515=IPI, GO:0005178=TAS, GO:0005887=TAS, GO:0006508=IEA, GO:0005576=IEA, GO:0008270=IEA, GO:0007417=TAS, GO:0007155=IEA, GO:0004222=IEA, GO:0008237=TAS} cell adhesion, central nervous system development, proteolysis extracellular region, integral to plasma membrane integrin binding, metalloendopeptidase activity, metallopeptidase activity, protein binding, zinc ion binding Human ADAM28 BHF-UCL UniProtKB {GO:0005886=GO_REF:0000039, GO:0007229=GO_REF:0000038, GO:0006508=GO_REF:0000037, GO:0005576=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0007283=PMID:10587367, GO:0016021=GO_REF:0000037, GO:0004222=GO_REF:0000002, GO:0008237=PMID:12777399} Q9UKQ2 Disintegrin and metalloproteinase domain-containing protein 28 protein 20110220 {GO:0005886=IEA, GO:0007229=IEA, GO:0006508=IEA, GO:0005576=IEA, GO:0008270=IEA, GO:0007283=TAS, GO:0016021=IEA, GO:0004222=IEA, GO:0008237=IDA} integrin-mediated signaling pathway, proteolysis, spermatogenesis extracellular region, integral to membrane, plasma membrane metalloendopeptidase activity, metallopeptidase activity, zinc ion binding Human ADAM29 PINC UniProtKB {GO:0005887=PMID:10512762, GO:0006508=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0007283=PMID:10512762, GO:0004222=GO_REF:0000002, GO:0008237=PMID:10512762} Q9UKF5 Disintegrin and metalloproteinase domain-containing protein 29 protein 20030904 {GO:0005887=TAS, GO:0006508=IEA, GO:0008270=IEA, GO:0007283=TAS, GO:0004222=IEA, GO:0008237=TAS} proteolysis, spermatogenesis integral to plasma membrane metalloendopeptidase activity, metallopeptidase activity, zinc ion binding Human ADAM33 UniProtKB UniProtKB {GO:0006508=PMID:11814695, GO:0008270=PMID:11814695, GO:0016021=PMID:11814695, GO:0004222=PMID:11814695} Q9BZ11 Disintegrin and metalloproteinase domain-containing protein 33 protein 20020812 {GO:0006508=NAS, GO:0008270=NAS, GO:0016021=NAS, GO:0004222=NAS} proteolysis integral to membrane metalloendopeptidase activity, zinc ion binding Human ADAM8 BHF-UCL UniProtKB {GO:0005515=PMID:12777399, GO:2000391=PMID:17548643, GO:0051897=GO_REF:0000024, GO:0033089=GO_REF:0000024, GO:0051044=PMID:15220135, GO:0005886=PMID:17548643, GO:2000418=GO_REF:0000024, GO:0035419=GO_REF:0000024, GO:2000415=GO_REF:0000024, GO:0071133=GO_REF:0000024, GO:0042581=PMID:17548643, GO:0050714=PMID:17548643, GO:0002102=PMID:15220135, GO:0032127=PMID:17548643, GO:0043621=PMID:12777399, GO:0043524=GO_REF:0000024, GO:0005737=PMID:18397961, GO:0016337=GO_REF:0000019, GO:0051092=GO_REF:0000024, GO:0006954=PMID:17548643, GO:0002675=GO_REF:0000024, GO:0045780=GO_REF:0000024, GO:0006508=GO_REF:0000037, GO:0032010=PMID:17548643, GO:0050839=PMID:12777399, GO:0022407=PMID:17548643, GO:0009986=PMID:17548643, GO:0002523=GO_REF:0000024, GO:0005509=GO_REF:0000024, GO:2000309=GO_REF:0000024, GO:0070245=GO_REF:0000024, GO:0071456=PMID:18566576, GO:0001525=GO_REF:0000024, GO:0045785=GO_REF:0000024, GO:0000902=GO_REF:0000024, GO:0010954=PMID:17548643, GO:0071065=PMID:15220135, GO:0005887=PMID:18397961, GO:0048247=GO_REF:0000024, GO:0008270=PMID:18397961, GO:0070820=PMID:17548643, GO:0004222=GO_REF:0000002, GO:0008237=PMID:12777399} P78325 Disintegrin and metalloproteinase domain-containing protein 8 protein 20110220 {GO:0005515=IPI, GO:2000391=IDA, GO:0051897=ISS, GO:0033089=ISS, GO:0051044=IDA, GO:0005886=IDA, GO:2000418=ISS, GO:0035419=ISS, GO:2000415=ISS, GO:0071133=ISS, GO:0042581=IDA, GO:0050714=IC, GO:0002102=IDA, GO:0032127=IDA, GO:0043621=TAS, GO:0043524=ISS, GO:0005737=IDA, GO:0016337=IEA, GO:0051092=ISS, GO:0006954=IDA, GO:0002675=ISS, GO:0045780=ISS, GO:0006508=IEA, GO:0032010=IDA, GO:0050839=IPI, GO:0022407=IDA, GO:0009986=IDA, GO:0002523=ISS, GO:0005509=ISS, GO:2000309=ISS, GO:0070245=ISS, GO:0071456=IDA, GO:0001525=ISS, GO:0045785=ISS, GO:0000902=ISS, GO:0010954=NAS, GO:0071065=IDA, GO:0005887=IDA, GO:0048247=ISS, GO:0008270=TAS, GO:0070820=IDA, GO:0004222=IEA, GO:0008237=IDA} activation of MAPK activity involved in innate immune response, angiogenesis, cell morphogenesis, cell-cell adhesion, cellular response to hypoxia, inflammatory response, leukocyte migration involved in inflammatory response, lymphocyte chemotaxis, negative regulation of neuron apoptotic process, positive regulation of NF-kappaB transcription factor activity, positive regulation of T cell differentiation in thymus, positive regulation of acute inflammatory response, positive regulation of bone resorption, positive regulation of cell adhesion, positive regulation of eosinophil migration, positive regulation of fibronectin-dependent thymocyte migration, positive regulation of membrane protein ectodomain proteolysis, positive regulation of neutrophil extravasation, positive regulation of protein kinase B signaling cascade, positive regulation of protein processing, positive regulation of protein secretion, positive regulation of thymocyte apoptotic process, positive regulation of tumor necrosis factor (ligand) superfamily member 11 production, proteolysis, regulation of cell-cell adhesion alpha9-beta1 integrin-ADAM8 complex, alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex, cell surface, cytoplasm, dense core granule membrane, integral to plasma membrane, phagolysosome, plasma membrane, podosome, specific granule, tertiary granule calcium ion binding, cell adhesion molecule binding, metalloendopeptidase activity, metallopeptidase activity, protein binding, protein self-association, zinc ion binding Human UniProtKB:Q05910 ADAM9 BHF-UCL UniProtKB {GO:0005515=PMID:15280379, GO:0042542=PMID:17018608, GO:0051044=PMID:8647900, GO:0017124=PMID:10531379, GO:0051549=PMID:17704059, GO:0005518=PMID:15361064, GO:0051088=PMID:9920899, GO:0005615=PMID:8647900, GO:0010042=PMID:11162558, GO:0005737=GO_REF:0000019, GO:0000186=PMID:17704059, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0005080=PMID:8647900, GO:0030574=Reactome:REACT_150401, GO:0006508=GO_REF:0000002, GO:0007179=PMID:8647900, GO:0006509=PMID:22480688, GO:0007155=PMID:11162558, GO:0034241=PMID:11831872, GO:0009986=PMID:8647900, GO:0051384=PMID:8647900, GO:0033631=PMID:17704059, GO:0031233=PMID:8647900, GO:0051592=PMID:11162558, GO:0071222=PMID:22480688, GO:0005178=PMID:11162558, GO:0007160=PMID:15361064, GO:0007229=PMID:11162558, GO:0030216=PMID:17704059, GO:0042117=PMID:11831872, GO:0043236=PMID:15361064, GO:0034612=PMID:11831872, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0004222=PMID:22480688, GO:0008237=PMID:12535668} Q13443 Disintegrin and metalloproteinase domain-containing protein 9 protein 20120704 {GO:0005515=IPI, GO:0042542=IMP, GO:0051044=ISS, GO:0017124=IPI, GO:0051549=IMP, GO:0005518=IMP, GO:0051088=TAS, GO:0005615=ISS, GO:0010042=IMP, GO:0005737=IEA, GO:0000186=IDA, GO:0022617=TAS, GO:0030198=TAS, GO:0005080=ISS, GO:0030574=TAS, GO:0006508=IEA, GO:0007179=ISS, GO:0006509=IMP, GO:0007155=IMP, GO:0034241=IMP, GO:0009986=ISS, GO:0051384=ISS, GO:0033631=IEP, GO:0031233=ISS, GO:0051592=IMP, GO:0071222=IMP, GO:0005178=IC, GO:0007160=IMP, GO:0007229=IC, GO:0030216=IEP, GO:0042117=IMP, GO:0043236=IMP, GO:0034612=IDA, GO:0008270=IEA, GO:0016021=IEA, GO:0004222=IMP, GO:0008237=IMP} PMA-inducible membrane protein ectodomain proteolysis, activation of MAPKK activity, cell adhesion, cell-cell adhesion mediated by integrin, cell-matrix adhesion, cellular response to lipopolysaccharide, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, integrin-mediated signaling pathway, keratinocyte differentiation, membrane protein ectodomain proteolysis, monocyte activation, positive regulation of keratinocyte migration, positive regulation of macrophage fusion, positive regulation of membrane protein ectodomain proteolysis, proteolysis, response to calcium ion, response to glucocorticoid stimulus, response to hydrogen peroxide, response to manganese ion, response to tumor necrosis factor, transforming growth factor beta receptor signaling pathway cell surface, cytoplasm, extracellular space, integral to membrane, intrinsic to external side of plasma membrane SH3 domain binding, collagen binding, integrin binding, laminin binding, metalloendopeptidase activity, metallopeptidase activity, protein binding, protein kinase C binding, zinc ion binding Human ADAMDEC1 UniProtKB UniProtKB {GO:0006955=PMID:12037602, GO:0007162=PMID:9271581, GO:0006508=GO_REF:0000037, GO:0008270=PMID:12037602, GO:0005576=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0004222=PMID:12037602} O15204 ADAM DEC1 protein 20111004 {GO:0006955=NAS, GO:0007162=NAS, GO:0006508=IEA, GO:0008270=NAS, GO:0005576=IEA, GO:0005575=ND, GO:0004222=NAS} immune response, negative regulation of cell adhesion, proteolysis cellular_component, extracellular region metalloendopeptidase activity, zinc ion binding Human ADAMTS1 PINC UniProtKB {GO:0060347=GO_REF:0000019, GO:0008285=PMID:10438512, GO:0007229=PMID:8995297, GO:0001822=GO_REF:0000019, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0001542=GO_REF:0000019, GO:0031410=GO_REF:0000019, GO:0004222=GO_REF:0000019, GO:0008201=GO_REF:0000019, GO:0008237=PMID:10438512, GO:0005604=GO_REF:0000019} Q9UHI8 A disintegrin and metalloproteinase with thrombospondin motifs 1 protein 20030904 {GO:0060347=IEA, GO:0008285=TAS, GO:0007229=TAS, GO:0001822=IEA, GO:0006508=IEA, GO:0008270=IEA, GO:0001542=IEA, GO:0031410=IEA, GO:0004222=IEA, GO:0008201=IEA, GO:0008237=TAS, GO:0005604=IEA} heart trabecula formation, integrin-mediated signaling pathway, kidney development, negative regulation of cell proliferation, ovulation from ovarian follicle, proteolysis basement membrane, cytoplasmic vesicle heparin binding, metalloendopeptidase activity, metallopeptidase activity, zinc ion binding Human ADAMTS10 UniProtKB UniProtKB {GO:0005515=PMID:21402694, GO:0031012=PMID:21402694, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005578=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0001527=PMID:21402694, GO:0008270=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0004222=GO_REF:0000002} Q9H324 A disintegrin and metalloproteinase with thrombospondin motifs 10 protein 20120620 {GO:0005515=IPI, GO:0031012=IDA, GO:0003674=ND, GO:0008150=ND, GO:0005578=IEA, GO:0006508=IEA, GO:0001527=IDA, GO:0008270=IEA, GO:0005575=ND, GO:0004222=IEA} biological_process, proteolysis cellular_component, extracellular matrix, microfibril, proteinaceous extracellular matrix metalloendopeptidase activity, molecular_function, protein binding, zinc ion binding Human UniProtKB:P35555 ADAMTS13 IntAct UniProtKB {GO:0005515=PMID:16221672, GO:0009986=PMID:11557746, GO:0005509=PMID:11557746, GO:0005578=PMID:11557746, GO:0030168=PMID:11557746, GO:0005615=GO_REF:0000019, GO:0009100=PMID:11557746, GO:0005178=PMID:11557746, GO:0007160=PMID:11557746, GO:0007229=PMID:11557746, GO:0016485=PMID:11557746, GO:0006508=PMID:11535495, GO:0008270=PMID:11557746, GO:0004222=GO_REF:0000002, GO:0043171=PMID:11535495, GO:0008237=PMID:11557746} Q76LX8 A disintegrin and metalloproteinase with thrombospondin motifs 13 protein 20130415 {GO:0005515=IPI, GO:0009986=NAS, GO:0005509=TAS, GO:0005578=TAS, GO:0030168=NAS, GO:0005615=IEA, GO:0009100=NAS, GO:0005178=TAS, GO:0007160=NAS, GO:0007229=NAS, GO:0016485=TAS, GO:0006508=IDA, GO:0008270=TAS, GO:0004222=IEA, GO:0043171=IDA, GO:0008237=TAS} cell-matrix adhesion, glycoprotein metabolic process, integrin-mediated signaling pathway, peptide catabolic process, platelet activation, protein processing, proteolysis cell surface, extracellular space, proteinaceous extracellular matrix calcium ion binding, integrin binding, metalloendopeptidase activity, metallopeptidase activity, protein binding, zinc ion binding Human UniProtKB:P04275 ADAMTS17 UniProtKB UniProtKB {GO:0006508=GO_REF:0000037, GO:0005578=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0004222=GO_REF:0000002} Q8TE56 A disintegrin and metalloproteinase with thrombospondin motifs 17 protein 20130413 {GO:0006508=IEA, GO:0005578=IEA, GO:0008270=IEA, GO:0004222=IEA} proteolysis proteinaceous extracellular matrix metalloendopeptidase activity, zinc ion binding Human UniProtKB-SubCell:SL-0111 ADAMTS2 Reactome UniProtKB {GO:0030324=GO_REF:0000019, GO:0005578=GO_REF:0000039, GO:0005576=Reactome:REACT_121172, GO:0007283=GO_REF:0000019, GO:0016485=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0030199=GO_REF:0000019, GO:0030574=GO_REF:0000037, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0043588=GO_REF:0000019, GO:0004222=GO_REF:0000002, GO:0008237=PMID:10417273} O95450 A disintegrin and metalloproteinase with thrombospondin motifs 2 protein 20130301 {GO:0030324=IEA, GO:0005578=IEA, GO:0005576=TAS, GO:0007283=IEA, GO:0016485=IEA, GO:0030198=TAS, GO:0030199=IEA, GO:0030574=IEA, GO:0006508=IEA, GO:0008270=IEA, GO:0043588=IEA, GO:0004222=IEA, GO:0008237=TAS} collagen catabolic process, collagen fibril organization, extracellular matrix organization, lung development, protein processing, proteolysis, skin development, spermatogenesis extracellular region, proteinaceous extracellular matrix metalloendopeptidase activity, metallopeptidase activity, zinc ion binding Human ADAMTS4 InterPro UniProtKB {GO:0005515=PMID:18718938, GO:0001501=PMID:10356395, GO:0005578=GO_REF:0000039, GO:0006508=GO_REF:0000002, GO:0008233=PMID:10751421, GO:0008270=GO_REF:0000002, GO:0002020=PMID:14744861, GO:0004222=GO_REF:0000002, GO:0005615=PMID:14744861, GO:0008237=PMID:10356395} Q5VTW1 A disintegrin and metalloproteinase with thrombospondin motifs 4 protein 20130413 {GO:0005515=IPI, GO:0001501=TAS, GO:0005578=IEA, GO:0006508=IEA, GO:0008233=TAS, GO:0008270=IEA, GO:0002020=IPI, GO:0004222=IEA, GO:0005615=IDA, GO:0008237=TAS} proteolysis, skeletal system development extracellular space, proteinaceous extracellular matrix metalloendopeptidase activity, metallopeptidase activity, peptidase activity, protease binding, protein binding, zinc ion binding Human InterPro:IPR002870 ADAMTS5 HPA UniProtKB {GO:0005515=PMID:22406378, GO:0005737=GO_REF:0000052, GO:0005178=PMID:10438522, GO:0005730=GO_REF:0000052, GO:0005578=GO_REF:0000039, GO:0006508=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0004222=GO_REF:0000002, GO:0008237=PMID:10438522} Q9UNA0 A disintegrin and metalloproteinase with thrombospondin motifs 5 protein 20120912 {GO:0005515=IPI, GO:0005737=IDA, GO:0005178=TAS, GO:0005730=IDA, GO:0005578=IEA, GO:0006508=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0004222=IEA, GO:0008237=TAS} proteolysis cytoplasm, nucleolus, nucleus, proteinaceous extracellular matrix integrin binding, metalloendopeptidase activity, metallopeptidase activity, protein binding, zinc ion binding Human ADAMTSL2 BHF-UCL UniProtKB {GO:0005515=PMID:18677313, GO:0005578=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0004222=GO_REF:0000002, GO:0030512=PMID:18677313} Q86TH1 ADAMTS-like protein 2 protein 20101031 {GO:0005515=IPI, GO:0005578=IEA, GO:0008270=IEA, GO:0004222=IEA, GO:0030512=IMP} negative regulation of transforming growth factor beta receptor signaling pathway proteinaceous extracellular matrix metalloendopeptidase activity, protein binding, zinc ion binding Human ADAMTSL4 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0031012=GO_REF:0000002, GO:0043065=PMID:16364318, GO:0030198=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0005575=GO_REF:0000015, GO:0002020=PMID:16364318, GO:0005614=GO_REF:0000019, GO:0004222=GO_REF:0000002} Q6UY14 ADAMTS-like protein 4 protein 20130415 {GO:0005515=IPI, GO:0031012=IEA, GO:0043065=IDA, GO:0030198=IEA, GO:0006915=IEA, GO:0005575=ND, GO:0002020=IPI, GO:0005614=IEA, GO:0004222=IEA} apoptotic process, extracellular matrix organization, positive regulation of apoptotic process cellular_component, extracellular matrix, interstitial matrix metalloendopeptidase activity, protease binding, protein binding Human UniProtKB:O75716 ADAMTSL5 InterPro UniProtKB {GO:0031012=GO_REF:0000002, GO:0005578=GO_REF:0000002, GO:0005576=GO_REF:0000038, GO:0008270=GO_REF:0000002, GO:0004222=GO_REF:0000002} Q6ZMM2 ADAMTS-like protein 5 protein 20130413 {GO:0031012=IEA, GO:0005578=IEA, GO:0005576=IEA, GO:0008270=IEA, GO:0004222=IEA} extracellular matrix, extracellular region, proteinaceous extracellular matrix metalloendopeptidase activity, zinc ion binding Human InterPro:IPR013273 ADAP1 HPA UniProtKB {GO:0005515=PMID:12893243, GO:0008060=PMID:10448098, GO:0043533=PMID:12018390, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0005886=PMID:10448098, GO:0032312=GO_REF:0000002, GO:0005634=PMID:10448098, GO:0008270=GO_REF:0000002, GO:0007166=PMID:10333475, GO:0043087=PMID:10333475} O75689 Arf-GAP with dual PH domain-containing protein 1 protein 20080205 {GO:0005515=IPI, GO:0008060=IDA, GO:0043533=TAS, GO:0005737=IDA, GO:0005543=IEA, GO:0005886=IDA, GO:0032312=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0007166=TAS, GO:0043087=IMP} cell surface receptor signaling pathway, regulation of ARF GTPase activity, regulation of GTPase activity cytoplasm, nucleus, plasma membrane ARF GTPase activator activity, inositol 1,3,4,5 tetrakisphosphate binding, phospholipid binding, protein binding, zinc ion binding Human ADAP2 GOC UniProtKB {GO:0005515=PMID:20098747, GO:0005886=PMID:14690521, GO:0043325=PMID:12018390, GO:0005547=PMID:14690521, GO:0005546=PMID:12018390, GO:0005740=PMID:12018390, GO:0043547=GO_REF:0000029, GO:0007507=PMID:16138909, GO:0008060=GO_REF:0000002, GO:0005737=PMID:14690521, GO:0043533=PMID:14690521, GO:0005543=GO_REF:0000002, GO:0032312=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0030674=PMID:14690521, GO:0005096=GO_REF:0000029} Q9NPF8 Arf-GAP with dual PH domain-containing protein 2 protein 20130413 {GO:0005515=IPI, GO:0005886=IDA, GO:0043325=ISS, GO:0005547=IDA, GO:0005546=ISS, GO:0005740=ISS, GO:0043547=NAS, GO:0007507=IEP, GO:0008060=IEA, GO:0005737=IDA, GO:0043533=IDA, GO:0005543=IEA, GO:0032312=IEA, GO:0008270=IEA, GO:0030674=NAS, GO:0005096=NAS} heart development, positive regulation of GTPase activity, regulation of ARF GTPase activity cytoplasm, mitochondrial envelope, plasma membrane ARF GTPase activator activity, GTPase activator activity, inositol 1,3,4,5 tetrakisphosphate binding, phosphatidylinositol-3,4,5-trisphosphate binding, phosphatidylinositol-3,4-bisphosphate binding, phosphatidylinositol-4,5-bisphosphate binding, phospholipid binding, protein binding, protein binding, bridging, zinc ion binding Human ADAR HPA UniProtKB {GO:0003725=GO_REF:0000002, GO:0005515=PMID:18362360, GO:0010467=Reactome:REACT_71, GO:0003726=PMID:9020165, GO:0035455=PMID:16475990, GO:0019221=Reactome:REACT_25229, GO:0005634=GO_REF:0000052, GO:0031047=GO_REF:0000037, GO:0006382=Reactome:REACT_18, GO:0046872=GO_REF:0000037, GO:0005737=PMID:7565688, GO:0051607=GO_REF:0000037, GO:0060337=Reactome:REACT_25162, GO:0044530=PMID:18362360, GO:0045070=PMID:19651874, GO:0006397=GO_REF:0000037, GO:0006396=GO_REF:0000002, GO:0043066=GO_REF:0000019, GO:0016556=Reactome:REACT_1757, GO:0016553=PMID:9020165, GO:0005730=GO_REF:0000039, GO:0009615=PMID:15858013, GO:0003677=GO_REF:0000037, GO:0044387=PMID:18362360, GO:0045087=PMID:16475990, GO:0005654=Reactome:REACT_25192} P55265 Double-stranded RNA-specific adenosine deaminase protein 20101115 {GO:0003725=IEA, GO:0005515=IPI, GO:0010467=TAS, GO:0003726=IDA, GO:0035455=IDA, GO:0019221=TAS, GO:0005634=IDA, GO:0031047=IEA, GO:0006382=TAS, GO:0046872=IEA, GO:0005737=TAS, GO:0051607=IEA, GO:0060337=TAS, GO:0044530=IDA, GO:0045070=IDA, GO:0006397=IEA, GO:0006396=IEA, GO:0043066=IEA, GO:0016556=TAS, GO:0016553=IDA, GO:0005730=IEA, GO:0009615=IMP, GO:0003677=IEA, GO:0044387=IMP, GO:0045087=TAS, GO:0005654=TAS} RNA processing, adenosine to inosine editing, base conversion or substitution editing, cytokine-mediated signaling pathway, defense response to virus, gene expression, gene silencing by RNA, innate immune response, mRNA modification, mRNA processing, negative regulation of apoptotic process, negative regulation of protein kinase activity by regulation of protein phosphorylation, positive regulation of viral genome replication, response to interferon-alpha, response to virus, type I interferon-mediated signaling pathway cytoplasm, nucleolus, nucleoplasm, nucleus, supraspliceosomal complex DNA binding, double-stranded RNA adenosine deaminase activity, double-stranded RNA binding, metal ion binding, protein binding Human ADARB1 BHF-UCL UniProtKB {GO:0003725=GO_REF:0000002, GO:0006397=GO_REF:0000037, GO:0010467=Reactome:REACT_71, GO:0006396=GO_REF:0000002, GO:0030336=PMID:18178553, GO:0008285=PMID:18178553, GO:0016556=Reactome:REACT_1757, GO:0005730=PMID:18178553, GO:0003729=PMID:9149227, GO:0006382=Reactome:REACT_18, GO:0046872=GO_REF:0000037, GO:0051607=GO_REF:0000037, GO:0004000=GO_REF:0000002, GO:0044387=PMID:21289159, GO:0045087=GO_REF:0000037, GO:0051726=PMID:18178553, GO:0005654=Reactome:REACT_990, GO:0045070=PMID:21289159} P78563 Double-stranded RNA-specific editase 1 protein 20090928 {GO:0003725=IEA, GO:0006397=IEA, GO:0010467=TAS, GO:0006396=IEA, GO:0030336=IDA, GO:0008285=IDA, GO:0016556=TAS, GO:0005730=IDA, GO:0003729=TAS, GO:0006382=TAS, GO:0046872=IEA, GO:0051607=IEA, GO:0004000=IEA, GO:0044387=IDA, GO:0045087=IEA, GO:0051726=IDA, GO:0005654=TAS, GO:0045070=IMP} RNA processing, adenosine to inosine editing, defense response to virus, gene expression, innate immune response, mRNA modification, mRNA processing, negative regulation of cell migration, negative regulation of cell proliferation, negative regulation of protein kinase activity by regulation of protein phosphorylation, positive regulation of viral genome replication, regulation of cell cycle nucleolus, nucleoplasm adenosine deaminase activity, double-stranded RNA binding, mRNA binding, metal ion binding Human ADARB2 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0006397=GO_REF:0000037, GO:0003725=GO_REF:0000002, GO:0006396=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0003727=PMID:10836796, GO:0004000=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0046872=GO_REF:0000037} Q9NS39 Double-stranded RNA-specific editase B2 protein 20101115 {GO:0005739=IDA, GO:0006397=IEA, GO:0003725=IEA, GO:0006396=IEA, GO:0005737=IDA, GO:0003727=TAS, GO:0004000=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0046872=IEA} RNA processing, mRNA processing cytoplasm, mitochondrion, nucleolus, nucleus RNA binding, adenosine deaminase activity, double-stranded RNA binding, metal ion binding, single-stranded RNA binding Human ADAT1 UniProtKB UniProtKB {GO:0006396=GO_REF:0000002, GO:0004000=GO_REF:0000002, GO:0003723=PMID:10430867, GO:0008251=PMID:10430867, GO:0008033=PMID:10430867, GO:0046872=GO_REF:0000037} Q9BUB4 tRNA-specific adenosine deaminase 1 protein 20080312 {GO:0006396=IEA, GO:0004000=IEA, GO:0003723=IMP, GO:0008251=IMP, GO:0008033=IMP, GO:0046872=IEA} RNA processing, tRNA processing RNA binding, adenosine deaminase activity, metal ion binding, tRNA-specific adenosine deaminase activity Human ADAT2 UniProtKB UniProtKB {GO:0016787=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0008033=GO_REF:0000037} Q7Z6V5 tRNA-specific adenosine deaminase 2 protein 20130413 {GO:0016787=IEA, GO:0008270=IEA, GO:0008033=IEA} tRNA processing hydrolase activity, zinc ion binding Human UniProtKB-KW:KW-0378 ADAT3 UniProtKB UniProtKB {GO:0016787=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0008033=GO_REF:0000037} Q96EY9 Probable inactive tRNA-specific adenosine deaminase-like protein 3 protein 20130413 {GO:0016787=IEA, GO:0008270=IEA, GO:0008033=IEA} tRNA processing hydrolase activity, zinc ion binding Human UniProtKB-KW:KW-0819 ADCK1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0016301=GO_REF:0000038, GO:0004674=GO_REF:0000037, GO:0005576=GO_REF:0000039, GO:0005524=GO_REF:0000037} Q9UIE6 Uncharacterized aarF domain-containing protein kinase 1 protein 20130413 {GO:0005739=IEA, GO:0016301=IEA, GO:0004674=IEA, GO:0005576=IEA, GO:0005524=IEA} extracellular region, mitochondrion ATP binding, kinase activity, protein serine/threonine kinase activity Human UniProtKB-KW:KW-0418 ADCK2 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q7Z695 Uncharacterized aarF domain-containing protein kinase 2 protein 20130413 {GO:0005739=IEA, GO:0004672=IEA, GO:0004674=IEA, GO:0016021=IEA, GO:0005524=IEA} integral to membrane, mitochondrion ATP binding, protein kinase activity, protein serine/threonine kinase activity Human Ensembl:ENSMUSP00000123563 ADCK3 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0008219=GO_REF:0000037, GO:0004674=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0016772=GO_REF:0000002} Q8NI60 Chaperone activity of bc1 complex-like, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0008219=IEA, GO:0004674=IEA, GO:0005524=IEA, GO:0016772=IEA} cell death mitochondrion ATP binding, protein serine/threonine kinase activity, transferase activity, transferring phosphorus-containing groups Human UniProtKB-SubCell:SL-0173 ADCK4 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0004674=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q96D53 Uncharacterized aarF domain-containing protein kinase 4 protein 20130413 {GO:0005739=IEA, GO:0004674=IEA, GO:0016021=IEA} integral to membrane, mitochondrion protein serine/threonine kinase activity Human Ensembl:ENSMUSP00000104015 ADCK5 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0004674=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q3MIX3 Uncharacterized aarF domain-containing protein kinase 5 protein 20130413 {GO:0005739=IEA, GO:0004674=IEA, GO:0016021=IEA} integral to membrane, mitochondrion protein serine/threonine kinase activity Human Ensembl:ENSMUSP00000125055 ADCY1 Reactome UniProtKB {GO:0005516=GO_REF:0000029, GO:0005886=Reactome:REACT_20564, GO:0007268=Reactome:REACT_13685, GO:0005634=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0007409=GO_REF:0000019, GO:0007202=Reactome:REACT_12079, GO:0007193=Reactome:REACT_15333, GO:0046872=GO_REF:0000037, GO:0035556=GO_REF:0000002, GO:0000166=GO_REF:0000038, GO:0007173=Reactome:REACT_9417, GO:0071377=Reactome:REACT_1665, GO:0006171=GO_REF:0000029, GO:0006833=Reactome:REACT_24023, GO:0034199=Reactome:REACT_15530, GO:0048011=Reactome:REACT_11061, GO:0007616=GO_REF:0000019, GO:0016849=GO_REF:0000002, GO:0042493=GO_REF:0000019, GO:0008294=PMID:8314585, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0007165=Reactome:REACT_12478, GO:0010226=GO_REF:0000019, GO:0006112=Reactome:REACT_1505, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0007623=GO_REF:0000019, GO:0016021=GO_REF:0000029, GO:0007189=Reactome:REACT_15312, GO:0009190=GO_REF:0000002} Q08828 Adenylate cyclase type 1 protein 20130301 {GO:0005516=NAS, GO:0005886=TAS, GO:0007268=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0007409=IEA, GO:0007202=TAS, GO:0007193=TAS, GO:0046872=IEA, GO:0035556=IEA, GO:0000166=IEA, GO:0007173=TAS, GO:0071377=TAS, GO:0006171=NAS, GO:0006833=TAS, GO:0034199=TAS, GO:0048011=TAS, GO:0007616=IEA, GO:0016849=IEA, GO:0042493=IEA, GO:0008294=NAS, GO:0055085=TAS, GO:0005524=IEA, GO:0007165=TAS, GO:0010226=IEA, GO:0006112=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0007623=IEA, GO:0016021=NAS, GO:0007189=TAS, GO:0009190=IEA} activation of phospholipase C activity, activation of protein kinase A activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, axonogenesis, cAMP biosynthetic process, cellular response to glucagon stimulus, circadian rhythm, cyclic nucleotide biosynthetic process, energy reserve metabolic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, intracellular signal transduction, long-term memory, neurotrophin TRK receptor signaling pathway, response to drug, response to lithium ion, signal transduction, small molecule metabolic process, synaptic transmission, transmembrane transport, water transport integral to membrane, nucleus, plasma membrane ATP binding, calcium- and calmodulin-responsive adenylate cyclase activity, calmodulin binding, metal ion binding, nucleotide binding, phosphorus-oxygen lyase activity Human ADCY10 PINC UniProtKB {GO:0030424=GO_REF:0000019, GO:0048471=GO_REF:0000039, GO:0000287=GO_REF:0000002, GO:0030145=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0045178=GO_REF:0000019, GO:0045177=GO_REF:0000019, GO:0007283=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0030425=GO_REF:0000019, GO:0005829=PMID:9874775, GO:0030426=GO_REF:0000019, GO:0035556=GO_REF:0000002, GO:0005737=PMID:9874775, GO:0004016=PMID:9874775, GO:0043025=GO_REF:0000019, GO:0006171=PMID:9874775, GO:0051117=GO_REF:0000019, GO:0005856=GO_REF:0000039} Q96PN6 Adenylate cyclase type 10 protein 20030904 {GO:0030424=IEA, GO:0048471=IEA, GO:0000287=IEA, GO:0030145=IEA, GO:0043065=IEA, GO:0005886=IEA, GO:0045178=IEA, GO:0045177=IEA, GO:0007283=IEA, GO:0005524=IEA, GO:0030425=IEA, GO:0005829=NAS, GO:0030426=IEA, GO:0035556=IEA, GO:0005737=TAS, GO:0004016=NAS, GO:0043025=IEA, GO:0006171=NAS, GO:0051117=IEA, GO:0005856=IEA} cAMP biosynthetic process, intracellular signal transduction, positive regulation of apoptotic process, spermatogenesis apical part of cell, axon, basal part of cell, cytoplasm, cytoskeleton, cytosol, dendrite, growth cone, neuronal cell body, perinuclear region of cytoplasm, plasma membrane ATP binding, ATPase binding, adenylate cyclase activity, magnesium ion binding, manganese ion binding Human ADCY2 BHF-UCL UniProtKB {GO:0005886=Reactome:REACT_19147, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0007202=Reactome:REACT_12079, GO:0007193=Reactome:REACT_15333, GO:0030425=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0005622=GO_REF:0000024, GO:0035556=GO_REF:0000002, GO:0005737=PMID:11549699, GO:0000166=GO_REF:0000038, GO:0007173=Reactome:REACT_9417, GO:0071377=Reactome:REACT_1665, GO:0006171=GO_REF:0000024, GO:0006833=Reactome:REACT_24023, GO:0034199=Reactome:REACT_15530, GO:0048011=Reactome:REACT_11061, GO:0046982=GO_REF:0000024, GO:0008179=GO_REF:0000024, GO:0008294=GO_REF:0000019, GO:0031683=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0043234=GO_REF:0000019, GO:0007165=Reactome:REACT_12478, GO:0004016=GO_REF:0000024, GO:0006112=Reactome:REACT_1505, GO:0016020=GO_REF:0000024, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0045121=GO_REF:0000024, GO:0007188=GO_REF:0000024, GO:0016021=GO_REF:0000029, GO:0007189=Reactome:REACT_15312} Q08462 Adenylate cyclase type 2 protein 20120516 {GO:0005886=TAS, GO:0007268=TAS, GO:0044281=TAS, GO:0007202=TAS, GO:0007193=TAS, GO:0030425=ISS, GO:0046872=IEA, GO:0005622=ISS, GO:0035556=IEA, GO:0005737=IDA, GO:0000166=IEA, GO:0007173=TAS, GO:0071377=TAS, GO:0006171=ISS, GO:0006833=TAS, GO:0034199=TAS, GO:0048011=TAS, GO:0046982=ISS, GO:0008179=ISS, GO:0008294=IEA, GO:0031683=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0043234=IEA, GO:0007165=TAS, GO:0004016=ISS, GO:0006112=TAS, GO:0016020=ISS, GO:0008543=TAS, GO:0045087=TAS, GO:0045121=ISS, GO:0007188=ISS, GO:0016021=NAS, GO:0007189=TAS} activation of phospholipase C activity, activation of protein kinase A activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, cAMP biosynthetic process, cellular response to glucagon stimulus, energy reserve metabolic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, signal transduction, small molecule metabolic process, synaptic transmission, transmembrane transport, water transport cytoplasm, dendrite, integral to membrane, intracellular, membrane, membrane raft, plasma membrane, protein complex ATP binding, G-protein beta/gamma-subunit complex binding, adenylate cyclase activity, adenylate cyclase binding, calcium- and calmodulin-responsive adenylate cyclase activity, metal ion binding, nucleotide binding, protein heterodimerization activity Human UniProtKB:G0TC75 ADCY3 Reactome UniProtKB {GO:0007608=GO_REF:0000037, GO:0005516=GO_REF:0000037, GO:0005886=Reactome:REACT_20564, GO:0007268=Reactome:REACT_13685, GO:0007202=Reactome:REACT_12079, GO:0044281=Reactome:REACT_111217, GO:0007193=Reactome:REACT_15333, GO:0046872=GO_REF:0000037, GO:0035556=GO_REF:0000002, GO:0005737=PMID:11549699, GO:0000166=GO_REF:0000038, GO:0007173=Reactome:REACT_9417, GO:0071377=Reactome:REACT_1665, GO:0006833=Reactome:REACT_24023, GO:0034199=Reactome:REACT_15530, GO:0048011=Reactome:REACT_11061, GO:0016849=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0007165=Reactome:REACT_12478, GO:0006112=Reactome:REACT_1505, GO:0004016=GO_REF:0000003, GO:0005887=PMID:9920776, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0007189=Reactome:REACT_15312, GO:0009190=GO_REF:0000002} O60266 Adenylate cyclase type 3 protein 20130301 {GO:0007608=IEA, GO:0005516=IEA, GO:0005886=TAS, GO:0007268=TAS, GO:0007202=TAS, GO:0044281=TAS, GO:0007193=TAS, GO:0046872=IEA, GO:0035556=IEA, GO:0005737=IDA, GO:0000166=IEA, GO:0007173=TAS, GO:0071377=TAS, GO:0006833=TAS, GO:0034199=TAS, GO:0048011=TAS, GO:0016849=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0007165=TAS, GO:0006112=TAS, GO:0004016=IEA, GO:0005887=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0007189=TAS, GO:0009190=IEA} activation of phospholipase C activity, activation of protein kinase A activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, cellular response to glucagon stimulus, cyclic nucleotide biosynthetic process, energy reserve metabolic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, sensory perception of smell, signal transduction, small molecule metabolic process, synaptic transmission, transmembrane transport, water transport cytoplasm, integral to plasma membrane, plasma membrane ATP binding, adenylate cyclase activity, calmodulin binding, metal ion binding, nucleotide binding, phosphorus-oxygen lyase activity Human ADCY4 BHF-UCL UniProtKB {GO:0005515=PMID:17081159, GO:0005886=Reactome:REACT_19147, GO:0007268=Reactome:REACT_13685, GO:0007202=Reactome:REACT_12079, GO:0044281=Reactome:REACT_111217, GO:0007193=Reactome:REACT_15333, GO:0046872=GO_REF:0000037, GO:0030425=GO_REF:0000019, GO:0005622=GO_REF:0000019, GO:0035556=GO_REF:0000002, GO:0005737=PMID:11549699, GO:0000166=GO_REF:0000038, GO:0007173=Reactome:REACT_9417, GO:0071377=Reactome:REACT_1665, GO:0006171=GO_REF:0000024, GO:0006833=Reactome:REACT_24023, GO:0034199=Reactome:REACT_15530, GO:0048011=Reactome:REACT_11061, GO:0016849=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0007165=Reactome:REACT_12478, GO:0004016=GO_REF:0000024, GO:0006112=Reactome:REACT_1505, GO:0016020=GO_REF:0000024, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0007188=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0007189=Reactome:REACT_15312, GO:0009190=GO_REF:0000002} Q8NFM4 Adenylate cyclase type 4 protein 20120516 {GO:0005515=IPI, GO:0005886=TAS, GO:0007268=TAS, GO:0007202=TAS, GO:0044281=TAS, GO:0007193=TAS, GO:0046872=IEA, GO:0030425=IEA, GO:0005622=IEA, GO:0035556=IEA, GO:0005737=IDA, GO:0000166=IEA, GO:0007173=TAS, GO:0071377=TAS, GO:0006171=ISS, GO:0006833=TAS, GO:0034199=TAS, GO:0048011=TAS, GO:0016849=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0007165=TAS, GO:0004016=ISS, GO:0006112=TAS, GO:0016020=ISS, GO:0008543=TAS, GO:0045087=TAS, GO:0007188=ISS, GO:0016021=IEA, GO:0007189=TAS, GO:0009190=IEA} activation of phospholipase C activity, activation of protein kinase A activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, cAMP biosynthetic process, cellular response to glucagon stimulus, cyclic nucleotide biosynthetic process, energy reserve metabolic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, signal transduction, small molecule metabolic process, synaptic transmission, transmembrane transport, water transport cytoplasm, dendrite, integral to membrane, intracellular, membrane, plasma membrane ATP binding, adenylate cyclase activity, metal ion binding, nucleotide binding, phosphorus-oxygen lyase activity, protein binding Human UniProtKB:P26770 ADCY5 BHF-UCL UniProtKB {GO:0005886=GO_REF:0000024, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0007195=GO_REF:0000019, GO:0007202=Reactome:REACT_12079, GO:0007193=Reactome:REACT_15333, GO:0046872=GO_REF:0000037, GO:0007191=GO_REF:0000019, GO:0035556=GO_REF:0000002, GO:0000166=GO_REF:0000038, GO:0007173=Reactome:REACT_9417, GO:0071377=Reactome:REACT_1665, GO:0050885=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0006833=Reactome:REACT_24023, GO:0034199=Reactome:REACT_15530, GO:0048011=Reactome:REACT_11061, GO:0046982=GO_REF:0000024, GO:0008179=GO_REF:0000024, GO:0072372=GO_REF:0000024, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0007165=Reactome:REACT_12478, GO:0004016=GO_REF:0000003, GO:0006112=Reactome:REACT_1505, GO:0001973=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0016021=GO_REF:0000037, GO:0007189=Reactome:REACT_15312} O95622 Adenylate cyclase type 5 protein 20120323 {GO:0005886=ISS, GO:0007268=TAS, GO:0044281=TAS, GO:0007195=IEA, GO:0007202=TAS, GO:0007193=TAS, GO:0046872=IEA, GO:0007191=IEA, GO:0035556=IEA, GO:0000166=IEA, GO:0007173=TAS, GO:0071377=TAS, GO:0050885=IEA, GO:0007626=IEA, GO:0006833=TAS, GO:0034199=TAS, GO:0048011=TAS, GO:0046982=ISS, GO:0008179=ISS, GO:0072372=ISS, GO:0055085=TAS, GO:0005524=IEA, GO:0007165=TAS, GO:0004016=IEA, GO:0006112=TAS, GO:0001973=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:0016021=IEA, GO:0007189=TAS} activation of phospholipase C activity, activation of protein kinase A activity, adenosine receptor signaling pathway, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-activating dopamine receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, adenylate cyclase-inhibiting dopamine receptor signaling pathway, cellular response to glucagon stimulus, energy reserve metabolic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, intracellular signal transduction, locomotory behavior, neuromuscular process controlling balance, neurotrophin TRK receptor signaling pathway, signal transduction, small molecule metabolic process, synaptic transmission, transmembrane transport, water transport integral to membrane, plasma membrane, primary cilium ATP binding, adenylate cyclase activity, adenylate cyclase binding, metal ion binding, nucleotide binding, protein heterodimerization activity Human UniProtKB:P84309 ADCY6 BHF-UCL UniProtKB {GO:0005515=PMID:17081159, GO:0005886=Reactome:REACT_19147, GO:0007268=Reactome:REACT_13685, GO:0007202=Reactome:REACT_12079, GO:0044281=Reactome:REACT_111217, GO:0071380=PMID:18403039, GO:0007193=Reactome:REACT_15333, GO:0046872=GO_REF:0000037, GO:0035556=GO_REF:0000002, GO:0007173=Reactome:REACT_9417, GO:0071377=Reactome:REACT_1665, GO:0006171=PMID:18403039, GO:0006833=Reactome:REACT_24023, GO:0034199=Reactome:REACT_15530, GO:0048011=Reactome:REACT_11061, GO:0019901=GO_REF:0000024, GO:0007212=PMID:18403039, GO:0005524=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0007165=Reactome:REACT_12478, GO:0005929=GO_REF:0000039, GO:0004016=PMID:18403039, GO:0006112=Reactome:REACT_1505, GO:0016020=GO_REF:0000024, GO:0008543=Reactome:REACT_9470, GO:0071870=PMID:18403039, GO:0045087=Reactome:REACT_6802, GO:0016021=GO_REF:0000037, GO:0007189=Reactome:REACT_15312} O43306 Adenylate cyclase type 6 protein 20120329 {GO:0005515=IPI, GO:0005886=TAS, GO:0007268=TAS, GO:0007202=TAS, GO:0044281=TAS, GO:0071380=IDA, GO:0007193=TAS, GO:0046872=IEA, GO:0035556=IEA, GO:0007173=TAS, GO:0071377=TAS, GO:0006171=IDA, GO:0006833=TAS, GO:0034199=TAS, GO:0048011=TAS, GO:0019901=ISS, GO:0007212=IDA, GO:0005524=IEA, GO:0055085=TAS, GO:0007165=TAS, GO:0005929=IEA, GO:0004016=IDA, GO:0006112=TAS, GO:0016020=ISS, GO:0008543=TAS, GO:0071870=IDA, GO:0045087=TAS, GO:0016021=IEA, GO:0007189=TAS} activation of phospholipase C activity, activation of protein kinase A activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, cAMP biosynthetic process, cellular response to catecholamine stimulus, cellular response to glucagon stimulus, cellular response to prostaglandin E stimulus, dopamine receptor signaling pathway, energy reserve metabolic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, signal transduction, small molecule metabolic process, synaptic transmission, transmembrane transport, water transport cilium, integral to membrane, membrane, plasma membrane ATP binding, adenylate cyclase activity, metal ion binding, protein binding, protein kinase binding Human ADCY7 Reactome UniProtKB {GO:0005886=Reactome:REACT_19147, GO:0030819=PMID:11113152, GO:0007268=Reactome:REACT_13685, GO:0007202=Reactome:REACT_12079, GO:0044281=Reactome:REACT_111217, GO:0007193=Reactome:REACT_15333, GO:0046872=GO_REF:0000037, GO:0035556=GO_REF:0000002, GO:0007173=Reactome:REACT_9417, GO:0071377=Reactome:REACT_1665, GO:0006833=Reactome:REACT_24023, GO:0034199=Reactome:REACT_15530, GO:0048011=Reactome:REACT_11061, GO:0016849=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0007165=Reactome:REACT_12478, GO:0071361=PMID:17760784, GO:0006112=Reactome:REACT_1505, GO:0004016=PMID:11113152, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0007189=Reactome:REACT_15312, GO:0016021=PMID:11113152, GO:0009190=GO_REF:0000002} P51828 Adenylate cyclase type 7 protein 20130301 {GO:0005886=TAS, GO:0030819=IDA, GO:0007268=TAS, GO:0007202=TAS, GO:0044281=TAS, GO:0007193=TAS, GO:0046872=IEA, GO:0035556=IEA, GO:0007173=TAS, GO:0071377=TAS, GO:0006833=TAS, GO:0034199=TAS, GO:0048011=TAS, GO:0016849=IEA, GO:0005524=IEA, GO:0055085=TAS, GO:0007165=TAS, GO:0071361=IDA, GO:0006112=TAS, GO:0004016=IDA, GO:0008543=TAS, GO:0045087=TAS, GO:0007189=TAS, GO:0016021=IDA, GO:0009190=IEA} activation of phospholipase C activity, activation of protein kinase A activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, cellular response to ethanol, cellular response to glucagon stimulus, cyclic nucleotide biosynthetic process, energy reserve metabolic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, positive regulation of cAMP biosynthetic process, signal transduction, small molecule metabolic process, synaptic transmission, transmembrane transport, water transport integral to membrane, plasma membrane ATP binding, adenylate cyclase activity, metal ion binding, phosphorus-oxygen lyase activity Human ADCY8 Reactome UniProtKB {GO:0005886=Reactome:REACT_20564, GO:0007268=Reactome:REACT_13685, GO:0007202=Reactome:REACT_12079, GO:0044281=Reactome:REACT_111217, GO:0007193=Reactome:REACT_15333, GO:0046872=GO_REF:0000037, GO:0035556=GO_REF:0000002, GO:0007173=Reactome:REACT_9417, GO:0000166=GO_REF:0000038, GO:0071377=Reactome:REACT_1665, GO:0007611=PMID:8076676, GO:0006833=Reactome:REACT_24023, GO:0034199=Reactome:REACT_15530, GO:0048011=Reactome:REACT_11061, GO:0007616=GO_REF:0000019, GO:0008294=PMID:8163524, GO:0005524=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0007165=Reactome:REACT_12478, GO:0006112=Reactome:REACT_1505, GO:0004016=PMID:8076676, GO:0016020=PMID:8163524, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0016021=GO_REF:0000037, GO:0007189=Reactome:REACT_15312} P40145 Adenylate cyclase type 8 protein 20130301 {GO:0005886=TAS, GO:0007268=TAS, GO:0007202=TAS, GO:0044281=TAS, GO:0007193=TAS, GO:0046872=IEA, GO:0035556=IEA, GO:0007173=TAS, GO:0000166=IEA, GO:0071377=TAS, GO:0007611=TAS, GO:0006833=TAS, GO:0034199=TAS, GO:0048011=TAS, GO:0007616=IEA, GO:0008294=TAS, GO:0005524=IEA, GO:0055085=TAS, GO:0007165=TAS, GO:0006112=TAS, GO:0004016=TAS, GO:0016020=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0016021=IEA, GO:0007189=TAS} activation of phospholipase C activity, activation of protein kinase A activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, cellular response to glucagon stimulus, energy reserve metabolic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, intracellular signal transduction, learning or memory, long-term memory, neurotrophin TRK receptor signaling pathway, signal transduction, small molecule metabolic process, synaptic transmission, transmembrane transport, water transport integral to membrane, membrane, plasma membrane ATP binding, adenylate cyclase activity, calcium- and calmodulin-responsive adenylate cyclase activity, metal ion binding, nucleotide binding Human ADCY9 Reactome UniProtKB {GO:0048011=Reactome:REACT_11061, GO:0016849=GO_REF:0000002, GO:0005886=Reactome:REACT_19147, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0007202=Reactome:REACT_12079, GO:0055085=Reactome:REACT_15518, GO:0007193=Reactome:REACT_15333, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0035556=GO_REF:0000002, GO:0007165=Reactome:REACT_12478, GO:0004016=GO_REF:0000003, GO:0006112=Reactome:REACT_1505, GO:0007173=Reactome:REACT_9417, GO:0071377=Reactome:REACT_1665, GO:0008543=Reactome:REACT_9470, GO:0005887=PMID:9628827, GO:0045087=Reactome:REACT_6802, GO:0006833=Reactome:REACT_24023, GO:0007189=Reactome:REACT_15312, GO:0034199=Reactome:REACT_15530, GO:0009190=GO_REF:0000002} O60503 Adenylate cyclase type 9 protein 20130301 {GO:0048011=TAS, GO:0016849=IEA, GO:0005886=TAS, GO:0007268=TAS, GO:0044281=TAS, GO:0007202=TAS, GO:0055085=TAS, GO:0007193=TAS, GO:0005524=IEA, GO:0046872=IEA, GO:0035556=IEA, GO:0007165=TAS, GO:0004016=IEA, GO:0006112=TAS, GO:0007173=TAS, GO:0071377=TAS, GO:0008543=TAS, GO:0005887=TAS, GO:0045087=TAS, GO:0006833=TAS, GO:0007189=TAS, GO:0034199=TAS, GO:0009190=IEA} activation of phospholipase C activity, activation of protein kinase A activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, cellular response to glucagon stimulus, cyclic nucleotide biosynthetic process, energy reserve metabolic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, signal transduction, small molecule metabolic process, synaptic transmission, transmembrane transport, water transport integral to plasma membrane, plasma membrane ATP binding, adenylate cyclase activity, metal ion binding, phosphorus-oxygen lyase activity Human ADCYAP1 BHF-UCL UniProtKB {GO:0032755=GO_REF:0000019, GO:0060124=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0070445=GO_REF:0000019, GO:0034259=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0021983=GO_REF:0000019, GO:0002865=GO_REF:0000019, GO:0016521=PMID:9603988, GO:0007267=PMID:2302217, GO:0043267=GO_REF:0000019, GO:0031858=GO_REF:0000019, GO:0051428=PMID:17470806, GO:0007204=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0032880=PMID:9603988, GO:0007190=Reactome:REACT_11046, GO:0001541=GO_REF:0000019, GO:0042594=GO_REF:0000019, GO:0043195=GO_REF:0000019, GO:0045909=GO_REF:0000019, GO:0001662=GO_REF:0000019, GO:0005184=PMID:2302217, GO:0048011=Reactome:REACT_11061, GO:0007565=PMID:10698193, GO:0046034=GO_REF:0000019, GO:0001821=GO_REF:0000019, GO:0002878=GO_REF:0000019, GO:0051968=GO_REF:0000019, GO:0005102=PMID:7680413, GO:0090274=GO_REF:0000019, GO:0010579=PMID:9603988, GO:0005576=Reactome:REACT_22268, GO:0060078=GO_REF:0000019, GO:0060253=GO_REF:0000019, GO:0045786=GO_REF:0000019, GO:0019233=GO_REF:0000019, GO:0071385=GO_REF:0000019, GO:0008277=PMID:11175907, GO:0010976=GO_REF:0000019, GO:0005057=GO_REF:0000019, GO:0007169=Reactome:REACT_11064} P18509 Pituitary adenylate cyclase-activating polypeptide protein 20120323 {GO:0032755=IEA, GO:0060124=IEA, GO:0008284=IEA, GO:0070445=IEA, GO:0034259=IEA, GO:0045471=IEA, GO:0021983=IEA, GO:0002865=IEA, GO:0016521=IDA, GO:0007267=TAS, GO:0043267=IEA, GO:0031858=IEA, GO:0051428=IPI, GO:0007204=IEA, GO:0005615=IEA, GO:0032880=IDA, GO:0007190=TAS, GO:0001541=IEA, GO:0042594=IEA, GO:0043195=IEA, GO:0045909=IEA, GO:0001662=IEA, GO:0005184=TAS, GO:0048011=TAS, GO:0007565=TAS, GO:0046034=IEA, GO:0001821=IEA, GO:0002878=IEA, GO:0051968=IEA, GO:0005102=IPI, GO:0090274=IEA, GO:0010579=IDA, GO:0005576=TAS, GO:0060078=IEA, GO:0060253=IEA, GO:0045786=IEA, GO:0019233=IEA, GO:0071385=IEA, GO:0008277=IDA, GO:0010976=IEA, GO:0005057=IEA, GO:0007169=TAS} ATP metabolic process, activation of adenylate cyclase activity, behavioral fear response, cell-cell signaling, cellular response to glucocorticoid stimulus, elevation of cytosolic calcium ion concentration, female pregnancy, histamine secretion, negative regulation of Rho GTPase activity, negative regulation of acute inflammatory response to antigenic stimulus, negative regulation of acute inflammatory response to non-antigenic stimulus, negative regulation of cell cycle, negative regulation of glial cell proliferation, negative regulation of potassium ion transport, neurotrophin TRK receptor signaling pathway, ovarian follicle development, pituitary gland development, positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway, positive regulation of cell proliferation, positive regulation of growth hormone secretion, positive regulation of interleukin-6 production, positive regulation of neuron projection development, positive regulation of somatostatin secretion, positive regulation of synaptic transmission, glutamatergic, positive regulation of vasodilation, regulation of G-protein coupled receptor protein signaling pathway, regulation of oligodendrocyte progenitor proliferation, regulation of postsynaptic membrane potential, regulation of protein localization, response to ethanol, response to starvation, sensory perception of pain, transmembrane receptor protein tyrosine kinase signaling pathway extracellular region, extracellular space, terminal bouton neuropeptide hormone activity, peptide hormone receptor binding, pituitary adenylate cyclase activating polypeptide activity, pituitary adenylate cyclase-activating polypeptide receptor binding, receptor binding, receptor signaling protein activity Human ADCYAP1R1 Reactome UniProtKB {GO:0005515=PMID:17470806, GO:0043005=GO_REF:0000019, GO:0030306=GO_REF:0000019, GO:0005886=Reactome:REACT_22268, GO:0010524=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0030819=GO_REF:0000019, GO:0060732=GO_REF:0000019, GO:0007202=GO_REF:0000019, GO:0007283=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0007190=Reactome:REACT_11046, GO:0004999=GO_REF:0000002, GO:0060548=GO_REF:0000019, GO:0004872=PMID:7902709, GO:0032355=GO_REF:0000019, GO:0005791=GO_REF:0000019, GO:0046545=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0009986=GO_REF:0000019, GO:0008179=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0033555=GO_REF:0000019, GO:0042923=GO_REF:0000019, GO:0005887=PMID:7902709, GO:0005901=GO_REF:0000019, GO:0019933=GO_REF:0000019, GO:0005923=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0007169=Reactome:REACT_11064, GO:0007166=PMID:7902709, GO:0005768=GO_REF:0000019} P41586 Pituitary adenylate cyclase-activating polypeptide type I receptor protein 20060921 {GO:0005515=IPI, GO:0043005=IEA, GO:0030306=IEA, GO:0005886=TAS, GO:0010524=IEA, GO:0045471=IEA, GO:0030819=IEA, GO:0060732=IEA, GO:0007202=IEA, GO:0007283=IEA, GO:0030154=IEA, GO:0007190=TAS, GO:0004999=IEA, GO:0060548=IEA, GO:0004872=TAS, GO:0032355=IEA, GO:0005791=IEA, GO:0046545=IEA, GO:0048011=TAS, GO:0009986=IEA, GO:0008179=IEA, GO:0042493=IEA, GO:0033555=IEA, GO:0042923=IEA, GO:0005887=TAS, GO:0005901=IEA, GO:0019933=IEA, GO:0005923=IEA, GO:0016021=IEA, GO:0007169=TAS, GO:0007166=TAS, GO:0005768=IEA} activation of adenylate cyclase activity, activation of phospholipase C activity, cAMP-mediated signaling, cell differentiation, cell surface receptor signaling pathway, development of primary female sexual characteristics, multicellular organismal response to stress, negative regulation of cell death, neurotrophin TRK receptor signaling pathway, positive regulation of cAMP biosynthetic process, positive regulation of calcium ion transport into cytosol, positive regulation of inositol phosphate biosynthetic process, response to drug, response to estradiol stimulus, response to ethanol, spermatogenesis, transmembrane receptor protein tyrosine kinase signaling pathway caveola, cell surface, endosome, integral to membrane, integral to plasma membrane, neuron projection, plasma membrane, rough endoplasmic reticulum, tight junction ADP-ribosylation factor binding, adenylate cyclase binding, neuropeptide binding, protein binding, receptor activity, vasoactive intestinal polypeptide receptor activity Human ADD1 InterPro UniProtKB {GO:0005516=GO_REF:0000037, GO:0048471=GO_REF:0000019, GO:0030036=PMID:3693401, GO:0020027=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0071300=GO_REF:0000019, GO:0005634=PMID:16289097, GO:0042803=PMID:7642559, GO:0046872=GO_REF:0000002, GO:0006921=Reactome:REACT_995, GO:0032092=PMID:7642559, GO:0006884=GO_REF:0000019, GO:0005829=Reactome:REACT_115808, GO:0030968=Reactome:REACT_18356, GO:0045807=GO_REF:0000019, GO:0051016=PMID:8626479, GO:0042608=GO_REF:0000019, GO:0051015=PMID:7642559, GO:0048873=GO_REF:0000019, GO:0035264=GO_REF:0000019, GO:0051017=PMID:3693401, GO:0046982=PMID:7642559, GO:0030507=PMID:7642559, GO:0014069=GO_REF:0000019, GO:0006915=Reactome:REACT_578, GO:0003779=PMID:1840603, GO:0001701=GO_REF:0000019, GO:0045766=GO_REF:0000019, GO:0000902=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0005198=GO_REF:0000019, GO:0030218=GO_REF:0000019, GO:0008290=PMID:8626479, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0008134=PMID:16289097} Q86XM2 ADD1 protein protein 20130413 {GO:0005516=IEA, GO:0048471=IEA, GO:0030036=IC, GO:0020027=IEA, GO:0005886=IEA, GO:0071300=IEA, GO:0005634=IDA, GO:0042803=IPI, GO:0046872=IEA, GO:0006921=TAS, GO:0032092=IDA, GO:0006884=IEA, GO:0005829=TAS, GO:0030968=TAS, GO:0045807=IEA, GO:0051016=IDA, GO:0042608=IEA, GO:0051015=IDA, GO:0048873=IEA, GO:0035264=IEA, GO:0051017=IDA, GO:0046982=IPI, GO:0030507=IDA, GO:0014069=IEA, GO:0006915=TAS, GO:0003779=TAS, GO:0001701=IEA, GO:0045766=IEA, GO:0000902=IEA, GO:0016020=IEA, GO:0005198=IEA, GO:0030218=IEA, GO:0008290=IDA, GO:0006987=TAS, GO:0044267=TAS, GO:0008134=IPI} actin cytoskeleton organization, actin filament bundle assembly, activation of signaling protein activity involved in unfolded protein response, apoptotic process, barbed-end actin filament capping, cell morphogenesis, cell volume homeostasis, cellular component disassembly involved in execution phase of apoptosis, cellular protein metabolic process, cellular response to retinoic acid, endoplasmic reticulum unfolded protein response, erythrocyte differentiation, hemoglobin metabolic process, homeostasis of number of cells within a tissue, in utero embryonic development, multicellular organism growth, positive regulation of angiogenesis, positive regulation of endocytosis, positive regulation of protein binding F-actin capping protein complex, cytosol, membrane, nucleus, perinuclear region of cytoplasm, plasma membrane, postsynaptic density T cell receptor binding, actin binding, actin filament binding, calmodulin binding, metal ion binding, protein heterodimerization activity, protein homodimerization activity, spectrin binding, structural molecule activity, transcription factor binding Human InterPro:IPR001303 ADD2 BHF-UCL UniProtKB {GO:0030097=GO_REF:0000019, GO:0005516=GO_REF:0000037, GO:0030036=PMID:3693401, GO:0005886=GO_REF:0000039, GO:0046982=PMID:7642559, GO:0030507=PMID:7642559, GO:0003779=PMID:1840603, GO:0042803=PMID:7642559, GO:0046872=GO_REF:0000002, GO:0032092=PMID:7642559, GO:0005737=GO_REF:0000037, GO:0051016=PMID:8626479, GO:0051015=PMID:7642559, GO:0016020=GO_REF:0000019, GO:0005198=GO_REF:0000019, GO:0008290=PMID:8626479, GO:0051017=PMID:3693401} P35612 Beta-adducin protein 20090205 {GO:0030097=IEA, GO:0005516=IEA, GO:0030036=IC, GO:0005886=IEA, GO:0046982=IPI, GO:0030507=IDA, GO:0003779=TAS, GO:0042803=IPI, GO:0046872=IEA, GO:0032092=IDA, GO:0005737=IEA, GO:0051016=IDA, GO:0051015=IDA, GO:0016020=IEA, GO:0005198=IEA, GO:0008290=IDA, GO:0051017=IDA} actin cytoskeleton organization, actin filament bundle assembly, barbed-end actin filament capping, hemopoiesis, positive regulation of protein binding F-actin capping protein complex, cytoplasm, membrane, plasma membrane actin binding, actin filament binding, calmodulin binding, metal ion binding, protein heterodimerization activity, protein homodimerization activity, spectrin binding, structural molecule activity Human ADD3 PINC UniProtKB {GO:0005516=GO_REF:0000037, GO:0000794=GO_REF:0000019, GO:0016020=PMID:8893809, GO:0005886=GO_REF:0000039, GO:0005911=GO_REF:0000019, GO:0005200=PMID:8893809, GO:0003779=GO_REF:0000037, GO:0005856=GO_REF:0000039, GO:0005938=GO_REF:0000019, GO:0046872=GO_REF:0000002} Q9UEY8 Gamma-adducin protein 20030904 {GO:0005516=IEA, GO:0000794=IEA, GO:0016020=TAS, GO:0005886=IEA, GO:0005911=IEA, GO:0005200=TAS, GO:0003779=IEA, GO:0005856=IEA, GO:0005938=IEA, GO:0046872=IEA} cell cortex, cell-cell junction, condensed nuclear chromosome, cytoskeleton, membrane, plasma membrane actin binding, calmodulin binding, metal ion binding, structural constituent of cytoskeleton Human ADH1A Reactome UniProtKB {GO:0004022=Reactome:REACT_121302, GO:0005515=PMID:16153155, GO:0006805=Reactome:REACT_13705, GO:0017144=Reactome:REACT_121388, GO:0006066=PMID:2347582, GO:0006069=Reactome:REACT_34, GO:0004024=PMID:9982, GO:0008270=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_121302} P07327 Alcohol dehydrogenase 1A protein 20130213 {GO:0004022=TAS, GO:0005515=IPI, GO:0006805=TAS, GO:0017144=TAS, GO:0006066=NAS, GO:0006069=TAS, GO:0004024=IDA, GO:0008270=IEA, GO:0044281=TAS, GO:0005829=TAS} alcohol metabolic process, drug metabolic process, ethanol oxidation, small molecule metabolic process, xenobiotic metabolic process cytosol alcohol dehydrogenase (NAD) activity, alcohol dehydrogenase activity, zinc-dependent, protein binding, zinc ion binding Human ADH1B Reactome UniProtKB {GO:0006805=Reactome:REACT_13705, GO:0004024=PMID:9982, GO:0006069=Reactome:REACT_34, GO:0016491=GO_REF:0000038, GO:0008270=PMID:9982, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_1431} P00325 Alcohol dehydrogenase 1B protein 20130213 {GO:0006805=TAS, GO:0004024=IDA, GO:0006069=TAS, GO:0016491=IEA, GO:0008270=IDA, GO:0044281=TAS, GO:0005829=TAS} ethanol oxidation, small molecule metabolic process, xenobiotic metabolic process cytosol alcohol dehydrogenase activity, zinc-dependent, oxidoreductase activity, zinc ion binding Human ADH1C Reactome UniProtKB {GO:0004022=PMID:6391957, GO:0006805=Reactome:REACT_13705, GO:0006069=Reactome:REACT_34, GO:0008270=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_1431} P00326 Alcohol dehydrogenase 1C protein 20130213 {GO:0004022=IDA, GO:0006805=TAS, GO:0006069=TAS, GO:0008270=IEA, GO:0044281=TAS, GO:0005829=TAS} ethanol oxidation, small molecule metabolic process, xenobiotic metabolic process cytosol alcohol dehydrogenase (NAD) activity, zinc ion binding Human ADH4 HPA UniProtKB {GO:0005503=PMID:15369820, GO:0006805=Reactome:REACT_13705, GO:0006066=PMID:3466164, GO:0006069=Reactome:REACT_34, GO:0006081=PMID:3466164, GO:0044281=Reactome:REACT_111217, GO:0046164=GO_REF:0000024, GO:0003960=GO_REF:0000024, GO:0001523=PMID:15369820, GO:0019841=PMID:10407146, GO:0042375=GO_REF:0000024, GO:0005829=Reactome:REACT_1431, GO:0004022=PMID:3466164, GO:0004032=GO_REF:0000019, GO:0051287=PMID:10407146, GO:0019115=PMID:3466164, GO:0004024=PMID:10407146, GO:0015630=GO_REF:0000052, GO:0042572=PMID:16787387, GO:0016620=PMID:3466164, GO:0016491=GO_REF:0000002, GO:0008270=PMID:10407146, GO:0004745=PMID:15369820} P08319 Alcohol dehydrogenase 4 protein 20100326 {GO:0005503=IDA, GO:0006805=TAS, GO:0006066=IDA, GO:0006069=TAS, GO:0006081=IDA, GO:0044281=TAS, GO:0046164=ISS, GO:0003960=ISS, GO:0001523=IDA, GO:0019841=IDA, GO:0042375=ISS, GO:0005829=TAS, GO:0004022=IDA, GO:0004032=IEA, GO:0051287=IDA, GO:0019115=IDA, GO:0004024=IDA, GO:0015630=IDA, GO:0042572=IDA, GO:0016620=IDA, GO:0016491=IEA, GO:0008270=IDA, GO:0004745=IDA} alcohol catabolic process, alcohol metabolic process, cellular aldehyde metabolic process, ethanol oxidation, quinone cofactor metabolic process, retinoid metabolic process, retinol metabolic process, small molecule metabolic process, xenobiotic metabolic process cytosol, microtubule cytoskeleton NAD binding, NADPH:quinone reductase activity, alcohol dehydrogenase (NAD) activity, alcohol dehydrogenase activity, zinc-dependent, alditol:NADP+ 1-oxidoreductase activity, all-trans retinal binding, benzaldehyde dehydrogenase activity, oxidoreductase activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, retinol binding, retinol dehydrogenase activity, zinc ion binding Human ADH5 UniProtKB UniProtKB {GO:0005504=PMID:8460164, GO:0006069=GO_REF:0000002, GO:0006068=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0009055=PMID:8460164, GO:0005634=GO_REF:0000019, GO:0051409=GO_REF:0000019, GO:0018119=GO_REF:0000019, GO:0045777=GO_REF:0000019, GO:0001523=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0004022=GO_REF:0000003, GO:0005739=GO_REF:0000019, GO:0003016=GO_REF:0000019, GO:0046294=GO_REF:0000019, GO:0051903=PMID:8460164, GO:0016491=GO_REF:0000038, GO:0032496=GO_REF:0000019, GO:0051775=PMID:8460164, GO:0018467=PMID:8460164, GO:0008270=PMID:6375718} P11766 Alcohol dehydrogenase class-3 protein 20080612 {GO:0005504=IDA, GO:0006069=IEA, GO:0006068=IEA, GO:0007568=IEA, GO:0009055=TAS, GO:0005634=IEA, GO:0051409=IEA, GO:0018119=IEA, GO:0045777=IEA, GO:0001523=IEA, GO:0042803=IEA, GO:0004022=IEA, GO:0005739=IEA, GO:0003016=IEA, GO:0046294=IEA, GO:0051903=TAS, GO:0016491=IEA, GO:0032496=IEA, GO:0051775=IDA, GO:0018467=IDA, GO:0008270=IDA} aging, ethanol catabolic process, ethanol oxidation, formaldehyde catabolic process, peptidyl-cysteine S-nitrosylation, positive regulation of blood pressure, respiratory system process, response to lipopolysaccharide, response to nitrosative stress, response to redox state, retinoid metabolic process mitochondrion, nucleus S-(hydroxymethyl)glutathione dehydrogenase activity, alcohol dehydrogenase (NAD) activity, electron carrier activity, fatty acid binding, formaldehyde dehydrogenase activity, oxidoreductase activity, protein homodimerization activity, zinc ion binding Human ADH6 Reactome UniProtKB {GO:0004022=PMID:1755855, GO:0006805=Reactome:REACT_13705, GO:0006069=Reactome:REACT_34, GO:0045471=PMID:1755855, GO:0016491=GO_REF:0000002, GO:0008270=PMID:1593644, GO:0044281=Reactome:REACT_111217, GO:0005575=GO_REF:0000015, GO:0005829=Reactome:REACT_1431} P28332 Alcohol dehydrogenase 6 protein 20130213 {GO:0004022=IDA, GO:0006805=TAS, GO:0006069=TAS, GO:0045471=IDA, GO:0016491=IEA, GO:0008270=NAS, GO:0044281=TAS, GO:0005575=ND, GO:0005829=TAS} ethanol oxidation, response to ethanol, small molecule metabolic process, xenobiotic metabolic process cellular_component, cytosol alcohol dehydrogenase (NAD) activity, oxidoreductase activity, zinc ion binding Human ADH7 GOC UniProtKB {GO:0006805=Reactome:REACT_13705, GO:0045471=PMID:9600267, GO:0044281=Reactome:REACT_111217, GO:0019841=PMID:9228021, GO:0005829=Reactome:REACT_1431, GO:0004022=PMID:8074657, GO:0005622=GO_REF:0000019, GO:0009617=PMID:11410738, GO:0005737=GO_REF:0000052, GO:0042573=GO_REF:0000019, GO:0004024=PMID:7876099, GO:0042572=GO_REF:0000019, GO:0004745=PMID:7876099, GO:0048019=PMID:9600267, GO:0010430=PMID:9600267, GO:0006069=Reactome:REACT_34, GO:0006068=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005576=PMID:9600267, GO:0001523=PMID:9600267, GO:0004031=PMID:9600267, GO:0035276=PMID:9228021, GO:1900116=PMID:9600267, GO:0008270=GO_REF:0000002, GO:0055114=PMID:7876099} P40394 Alcohol dehydrogenase class 4 mu/sigma chain protein 20130413 {GO:0006805=TAS, GO:0045471=IDA, GO:0044281=TAS, GO:0019841=IDA, GO:0005829=TAS, GO:0004022=TAS, GO:0005622=IEA, GO:0009617=IDA, GO:0005737=IDA, GO:0042573=IEA, GO:0004024=IDA, GO:0042572=IEA, GO:0004745=IDA, GO:0048019=IDA, GO:0010430=IDA, GO:0006069=TAS, GO:0006068=IEA, GO:0005730=IDA, GO:0005576=IDA, GO:0001523=IDA, GO:0004031=IDA, GO:0035276=IDA, GO:1900116=IDA, GO:0008270=IEA, GO:0055114=IDA} ethanol catabolic process, ethanol oxidation, extracellular negative regulation of signal transduction, fatty acid omega-oxidation, oxidation-reduction process, response to bacterium, response to ethanol, retinoic acid metabolic process, retinoid metabolic process, retinol metabolic process, small molecule metabolic process, xenobiotic metabolic process cytoplasm, cytosol, extracellular region, intracellular, nucleolus alcohol dehydrogenase (NAD) activity, alcohol dehydrogenase activity, zinc-dependent, aldehyde oxidase activity, ethanol binding, receptor antagonist activity, retinol binding, retinol dehydrogenase activity, zinc ion binding Human ADHFE1 Reactome UniProtKB {GO:0005739=GO_REF:0000024, GO:0047988=PMID:16435184, GO:0005759=Reactome:REACT_25102, GO:0006103=Reactome:REACT_25367, GO:0016491=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0015993=PMID:16435184, GO:0046872=GO_REF:0000002} Q8IWW8 Hydroxyacid-oxoacid transhydrogenase, mitochondrial protein 20130301 {GO:0005739=ISS, GO:0047988=IDA, GO:0005759=TAS, GO:0006103=TAS, GO:0016491=IEA, GO:0044281=TAS, GO:0015993=IDA, GO:0046872=IEA} 2-oxoglutarate metabolic process, molecular hydrogen transport, small molecule metabolic process mitochondrial matrix, mitochondrion hydroxyacid-oxoacid transhydrogenase activity, metal ion binding, oxidoreductase activity Human ADI1 HPA UniProtKB {GO:0005515=PMID:14718544, GO:0005794=GO_REF:0000052, GO:0005886=PMID:14718544, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_75861, GO:0034641=Reactome:REACT_13, GO:0005737=PMID:11602742, GO:0000096=Reactome:REACT_115639, GO:0019509=Reactome:REACT_75881, GO:0006595=Reactome:REACT_14820, GO:0016491=PMID:15938715, GO:0010309=Reactome:REACT_75861} Q9BV57 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase protein 20110516 {GO:0005515=IPI, GO:0005794=IDA, GO:0005886=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0034641=TAS, GO:0005737=IDA, GO:0000096=TAS, GO:0019509=TAS, GO:0006595=TAS, GO:0016491=IDA, GO:0010309=TAS} L-methionine salvage from methylthioadenosine, cellular nitrogen compound metabolic process, polyamine metabolic process, small molecule metabolic process, sulfur amino acid metabolic process Golgi apparatus, cytoplasm, cytosol, nucleolus, nucleus, plasma membrane "acireductone dioxygenase iron(II)-requiring"" activity, metal ion binding, oxidoreductase activity, protein binding""" Human ADIPOQ BHF-UCL UniProtKB {GO:0005515=PMID:12070119, GO:0043499=PMID:10982546, GO:0045599=PMID:12021245, GO:0033211=GO_REF:0000019, GO:0050731=GO_REF:0000019, GO:0006091=PMID:10095105, GO:0010739=PMID:10982546, GO:0005615=PMID:10403784, GO:0042803=PMID:12021245, GO:0010906=PMID:17327472, GO:0032757=PMID:19524870, GO:0042802=PMID:10961870, GO:0070208=GO_REF:0000019, GO:0046888=GO_REF:0000019, GO:0045923=PMID:12368907, GO:0071639=PMID:19524870, GO:0009744=GO_REF:0000019, GO:0046326=PMID:12368907, GO:0034115=PMID:10604883, GO:2000461=PMID:12070119, GO:0051260=GO_REF:0000024, GO:0070373=PMID:12070119, GO:0033691=PMID:19855092, GO:0033034=PMID:10961870, GO:0043123=GO_REF:0000024, GO:0043124=PMID:10982546, GO:2000481=PMID:19524870, GO:2000467=GO_REF:0000024, GO:0030336=GO_REF:0000024, GO:0019395=GO_REF:0000024, GO:0032869=GO_REF:0000024, GO:0006635=PMID:12368907, GO:0010745=PMID:11222466, GO:0032720=PMID:10961870, GO:0051384=GO_REF:0000019, GO:0005125=PMID:12611609, GO:0010804=PMID:10604883, GO:0045650=PMID:10961870, GO:0032270=PMID:18703020, GO:0070543=GO_REF:0000019, GO:0060081=GO_REF:0000019, GO:0070994=GO_REF:0000024, GO:0005179=PMID:11222466, GO:0071872=GO_REF:0000019, GO:0050873=GO_REF:0000024, GO:0090317=PMID:18431508, GO:0050805=PMID:17327472, GO:2000279=PMID:12070119, GO:0007623=GO_REF:0000019, GO:2000478=GO_REF:0000024, GO:0045892=PMID:18431508, GO:0005581=GO_REF:0000037, GO:0051899=GO_REF:0000019, GO:0005783=GO_REF:0000024, GO:0045471=GO_REF:0000019, GO:2000534=PMID:18431508, GO:0045776=PMID:17327472, GO:0045777=GO_REF:0000019, GO:0010875=PMID:18703020, GO:0014912=PMID:12070119, GO:0031953=PMID:12070119, GO:0050765=PMID:10961870, GO:0034383=PMID:11222466, GO:0043407=GO_REF:0000024, GO:0030853=PMID:10961870, GO:0006006=PMID:12368907, GO:0010642=PMID:12070119, GO:0045721=PMID:12368907, GO:0001666=GO_REF:0000019, GO:0014823=GO_REF:0000019, GO:2000584=GO_REF:0000024, GO:0007584=GO_REF:0000019, GO:0005102=PMID:12368907, GO:0009967=PMID:12368907, GO:0045715=PMID:11222466, GO:0005576=Reactome:REACT_27292, GO:0048662=PMID:12070119, GO:0042593=PMID:12368907, GO:0035690=GO_REF:0000024, GO:0072659=PMID:18431508, GO:0009749=PMID:12368907, GO:0050728=PMID:12611609, GO:2000590=GO_REF:0000024, GO:0001934=PMID:18431508, GO:0034612=PMID:10604883, GO:0071320=GO_REF:0000019} Q15848 Adiponectin protein 20090424 {GO:0005515=IPI, GO:0043499=IDA, GO:0045599=IDA, GO:0033211=IEA, GO:0050731=IEA, GO:0006091=TAS, GO:0010739=IDA, GO:0005615=IDA, GO:0042803=IPI, GO:0010906=IDA, GO:0032757=IDA, GO:0042802=TAS, GO:0070208=IEA, GO:0046888=IEA, GO:0045923=ISS, GO:0071639=IDA, GO:0009744=IEA, GO:0046326=ISS, GO:0034115=IDA, GO:2000461=IDA, GO:0051260=ISS, GO:0070373=IDA, GO:0033691=IDA, GO:0033034=IDA, GO:0043123=ISS, GO:0043124=IDA, GO:2000481=IDA, GO:2000467=ISS, GO:0030336=ISS, GO:0019395=ISS, GO:0032869=ISS, GO:0006635=ISS, GO:0010745=IDA, GO:0032720=IDA, GO:0051384=IEA, GO:0005125=NAS, GO:0010804=IDA, GO:0045650=IDA, GO:0032270=IDA, GO:0070543=IEA, GO:0060081=IEA, GO:0070994=ISS, GO:0005179=IDA, GO:0071872=IEA, GO:0050873=ISS, GO:0090317=IDA, GO:0050805=IDA, GO:2000279=IDA, GO:0007623=IEA, GO:2000478=ISS, GO:0045892=IDA, GO:0005581=IEA, GO:0051899=IEA, GO:0005783=ISS, GO:0045471=IEA, GO:2000534=IDA, GO:0045776=IDA, GO:0045777=IEA, GO:0010875=IDA, GO:0014912=IDA, GO:0031953=IDA, GO:0050765=IDA, GO:0034383=IDA, GO:0043407=ISS, GO:0030853=IDA, GO:0006006=ISS, GO:0010642=IDA, GO:0045721=ISS, GO:0001666=IEA, GO:0014823=IEA, GO:2000584=ISS, GO:0007584=IEA, GO:0005102=ISS, GO:0009967=ISS, GO:0045715=IDA, GO:0005576=TAS, GO:0048662=IDA, GO:0042593=ISS, GO:0035690=ISS, GO:0072659=IDA, GO:0009749=ISS, GO:0050728=NAS, GO:2000590=ISS, GO:0001934=IDA, GO:0034612=IDA, GO:0071320=IEA} adiponectin-mediated signaling pathway, brown fat cell differentiation, cellular response to cAMP, cellular response to drug, cellular response to epinephrine stimulus, cellular response to insulin stimulus, circadian rhythm, detection of oxidative stress, fatty acid beta-oxidation, fatty acid oxidation, generation of precursor metabolites and energy, glucose homeostasis, glucose metabolic process, low-density lipoprotein particle clearance, membrane depolarization, membrane hyperpolarization, negative regulation of DNA biosynthetic process, negative regulation of ERK1 and ERK2 cascade, negative regulation of I-kappaB kinase/NF-kappaB cascade, negative regulation of MAP kinase activity, negative regulation of blood pressure, negative regulation of cell migration, negative regulation of eukaryotic cell surface binding, negative regulation of fat cell differentiation, negative regulation of gluconeogenesis, negative regulation of granulocyte differentiation, negative regulation of heterotypic cell-cell adhesion, negative regulation of hormone secretion, negative regulation of inflammatory response, negative regulation of intracellular protein transport, negative regulation of low-density lipoprotein particle receptor biosynthetic process, negative regulation of macrophage derived foam cell differentiation, negative regulation of macrophage differentiation, negative regulation of metanephric mesenchymal cell migration, negative regulation of phagocytosis, negative regulation of platelet-derived growth factor receptor signaling pathway, negative regulation of platelet-derived growth factor receptor-alpha signaling pathway, negative regulation of protein autophosphorylation, negative regulation of smooth muscle cell migration, negative regulation of smooth muscle cell proliferation, negative regulation of synaptic transmission, negative regulation of transcription, DNA-dependent, negative regulation of tumor necrosis factor production, negative regulation of tumor necrosis factor-mediated signaling pathway, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of blood pressure, positive regulation of cAMP-dependent protein kinase activity, positive regulation of cellular protein metabolic process, positive regulation of cholesterol efflux, positive regulation of fatty acid metabolic process, positive regulation of glucose import, positive regulation of glycogen (starch) synthase activity, positive regulation of interleukin-8 production, positive regulation of metanephric glomerular visceral epithelial cell development, positive regulation of monocyte chemotactic protein-1 production, positive regulation of myeloid cell apoptotic process, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of protein kinase A signaling cascade, positive regulation of protein phosphorylation, positive regulation of renal albumin absorption, positive regulation of signal transduction, protein heterotrimerization, protein homooligomerization, protein localization to plasma membrane, regulation of glucose metabolic process, response to activity, response to ethanol, response to glucocorticoid stimulus, response to glucose stimulus, response to hypoxia, response to linoleic acid, response to nutrient, response to sucrose stimulus, response to tumor necrosis factor collagen, endoplasmic reticulum, extracellular region, extracellular space cytokine activity, eukaryotic cell surface binding, hormone activity, identical protein binding, protein binding, protein homodimerization activity, receptor binding, sialic acid binding Human ADIPOR1 BHF-UCL UniProtKB {GO:0019395=PMID:12802337, GO:0009755=PMID:12802337, GO:0019901=PMID:19233263, GO:0005886=PMID:19233263, GO:0046982=GO_REF:0000019, GO:0042562=PMID:12802337, GO:0004872=GO_REF:0000019, GO:0016021=PMID:12802337, GO:0042802=GO_REF:0000019} Q96A54 Adiponectin receptor protein 1 protein 20100202 {GO:0019395=IDA, GO:0009755=IDA, GO:0019901=IPI, GO:0005886=IDA, GO:0046982=IEA, GO:0042562=IDA, GO:0004872=IEA, GO:0016021=NAS, GO:0042802=IEA} fatty acid oxidation, hormone-mediated signaling pathway integral to membrane, plasma membrane hormone binding, identical protein binding, protein heterodimerization activity, protein kinase binding, receptor activity Human UniProtKB:P67870 ADIPOR2 UniProtKB UniProtKB {GO:0019395=PMID:12802337, GO:0009755=PMID:12802337, GO:0046982=GO_REF:0000019, GO:0042562=PMID:12802337, GO:0004872=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0042802=GO_REF:0000019} Q86V24 Adiponectin receptor protein 2 protein 20041006 {GO:0019395=ISS, GO:0009755=ISS, GO:0046982=IEA, GO:0042562=ISS, GO:0004872=IEA, GO:0016021=IEA, GO:0042802=IEA} fatty acid oxidation, hormone-mediated signaling pathway integral to membrane hormone binding, identical protein binding, protein heterodimerization activity, receptor activity Human UniProtKB:Q96A54 ADK Reactome UniProtKB {GO:0046085=GO_REF:0000019, GO:0055086=Reactome:REACT_1698, GO:0005634=GO_REF:0000019, GO:0044209=GO_REF:0000041, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0009156=PMID:9070863, GO:0046872=GO_REF:0000037, GO:0032922=GO_REF:0000019, GO:0005829=Reactome:REACT_1728, GO:0006166=GO_REF:0000019, GO:0044342=GO_REF:0000019, GO:0006144=Reactome:REACT_522, GO:0004001=Reactome:REACT_1728, GO:0042102=GO_REF:0000019, GO:0043101=Reactome:REACT_1923, GO:0016773=GO_REF:0000002, GO:0006175=GO_REF:0000019, GO:0010613=GO_REF:0000019} P55263 Adenosine kinase protein 20130213 {GO:0046085=IEA, GO:0055086=TAS, GO:0005634=IEA, GO:0044209=IEA, GO:0044281=TAS, GO:0005524=IEA, GO:0009156=TAS, GO:0046872=IEA, GO:0032922=IEA, GO:0005829=TAS, GO:0006166=IEA, GO:0044342=IEA, GO:0006144=TAS, GO:0004001=EXP, GO:0042102=IEA, GO:0043101=TAS, GO:0016773=IEA, GO:0006175=IEA, GO:0010613=IEA} AMP salvage, adenosine metabolic process, circadian regulation of gene expression, dATP biosynthetic process, nucleobase-containing small molecule metabolic process, positive regulation of T cell proliferation, positive regulation of cardiac muscle hypertrophy, purine nucleobase metabolic process, purine ribonucleoside salvage, purine-containing compound salvage, ribonucleoside monophosphate biosynthetic process, small molecule metabolic process, type B pancreatic cell proliferation cytosol, nucleus ATP binding, adenosine kinase activity, metal ion binding, phosphotransferase activity, alcohol group as acceptor Human ADM BHF-UCL UniProtKB {GO:0005515=PMID:20074556, GO:0008284=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0031700=GO_REF:0000019, GO:0006701=PMID:10822232, GO:2001214=GO_REF:0000019, GO:0060712=GO_REF:0000019, GO:0031102=GO_REF:0000019, GO:0008015=PMID:8074714, GO:0060670=GO_REF:0000019, GO:0009409=GO_REF:0000019, GO:0031100=GO_REF:0000019, GO:0007267=PMID:8074714, GO:0007204=GO_REF:0000019, GO:0005615=PMID:12379507, GO:0031623=PMID:15613468, GO:0007507=GO_REF:0000019, GO:0005737=PMID:12379507, GO:0048589=GO_REF:0000019, GO:0042594=GO_REF:0000019, GO:0045906=PMID:11410113, GO:0045909=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0006171=PMID:20074556, GO:0042475=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0032868=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:0008209=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0005102=PMID:8524787, GO:0009611=GO_REF:0000019, GO:0001843=GO_REF:0000019, GO:0005576=Reactome:REACT_22268, GO:0051384=GO_REF:0000019, GO:0045766=GO_REF:0000019, GO:0046879=GO_REF:0000019, GO:0007165=PMID:10822232, GO:0005179=GO_REF:0000037, GO:0002026=GO_REF:0000019, GO:0019933=GO_REF:0000019, GO:0010460=GO_REF:0000019, GO:0097084=GO_REF:0000019, GO:0001570=PMID:16964401, GO:0043116=GO_REF:0000019} P35318 ADM protein 20080215 {GO:0005515=IPI, GO:0008284=IEA, GO:0008285=IEA, GO:0031700=IEA, GO:0006701=TAS, GO:2001214=IEA, GO:0060712=IEA, GO:0031102=IEA, GO:0008015=TAS, GO:0060670=IEA, GO:0009409=IEA, GO:0031100=IEA, GO:0007267=TAS, GO:0007204=IEA, GO:0005615=IDA, GO:0031623=IDA, GO:0007507=IEA, GO:0005737=IDA, GO:0048589=IEA, GO:0042594=IEA, GO:0045906=IDA, GO:0045909=IEA, GO:0032496=IEA, GO:0006171=IDA, GO:0042475=IEA, GO:0001666=IEA, GO:0032868=IEA, GO:0007565=IEA, GO:0008209=IEA, GO:0007568=IEA, GO:0005102=TAS, GO:0009611=IEA, GO:0001843=IEA, GO:0005576=TAS, GO:0051384=IEA, GO:0045766=IEA, GO:0046879=IEA, GO:0007165=TAS, GO:0005179=IEA, GO:0002026=IEA, GO:0019933=IEA, GO:0010460=IEA, GO:0097084=IEA, GO:0001570=IDA, GO:0043116=IEA} aging, androgen metabolic process, blood circulation, branching involved in labyrinthine layer morphogenesis, cAMP biosynthetic process, cAMP-mediated signaling, cell-cell signaling, developmental growth, elevation of cytosolic calcium ion concentration, female pregnancy, heart development, hormone secretion, negative regulation of cell proliferation, negative regulation of vascular permeability, negative regulation of vasoconstriction, neural tube closure, neuron projection regeneration, odontogenesis of dentin-containing tooth, organ regeneration, positive regulation of angiogenesis, positive regulation of cell proliferation, positive regulation of heart rate, positive regulation of vasculogenesis, positive regulation of vasodilation, progesterone biosynthetic process, receptor internalization, regulation of the force of heart contraction, response to cold, response to glucocorticoid stimulus, response to hypoxia, response to insulin stimulus, response to lipopolysaccharide, response to starvation, response to wounding, signal transduction, spongiotrophoblast layer development, vascular smooth muscle cell development, vasculogenesis cytoplasm, extracellular region, extracellular space adrenomedullin receptor binding, hormone activity, protein binding, receptor binding Human ADM2 Reactome UniProtKB {GO:0007631=GO_REF:0000019, GO:0005179=GO_REF:0000037, GO:0007586=GO_REF:0000019, GO:0005576=Reactome:REACT_22268, GO:0001525=PMID:20596610, GO:0045776=GO_REF:0000019, GO:0007189=GO_REF:0000019, GO:0032403=PMID:20596610, GO:0045766=PMID:19592612} Q7Z4H4 ADM2 protein 20130213 {GO:0007631=IEA, GO:0005179=IEA, GO:0007586=IEA, GO:0005576=TAS, GO:0001525=IDA, GO:0045776=IEA, GO:0007189=IEA, GO:0032403=IDA, GO:0045766=IDA} adenylate cyclase-activating G-protein coupled receptor signaling pathway, angiogenesis, digestion, feeding behavior, negative regulation of blood pressure, positive regulation of angiogenesis extracellular region hormone activity, protein complex binding Human ADNP HPA UniProtKB {GO:0005515=PMID:21888893, GO:0043565=GO_REF:0000002, GO:0043524=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0003682=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0005615=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q9H2P0 Activity-dependent neuroprotector homeobox protein protein 20080818 {GO:0005515=IPI, GO:0043565=IEA, GO:0043524=IEA, GO:0003700=IEA, GO:0003682=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0005615=IEA, GO:0006351=IEA} negative regulation of neuron apoptotic process, transcription, DNA-dependent extracellular space, nucleolus, nucleus chromatin binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding NOT Human ADNP2 IntAct UniProtKB {GO:0005515=PMID:21888893, GO:0003700=GO_REF:0000002, GO:0030307=GO_REF:0000024, GO:0071300=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0030182=GO_REF:0000024, GO:0060548=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0034599=GO_REF:0000024} Q6IQ32 ADNP homeobox protein 2 protein 20130415 {GO:0005515=IPI, GO:0003700=IEA, GO:0030307=ISS, GO:0071300=ISS, GO:0005634=IEA, GO:0005575=ND, GO:0006351=IEA, GO:0043565=IEA, GO:0003674=ND, GO:0030182=ISS, GO:0060548=ISS, GO:0008270=IEA, GO:0034599=ISS} cellular response to oxidative stress, cellular response to retinoic acid, negative regulation of cell death, neuron differentiation, positive regulation of cell growth, transcription, DNA-dependent cellular_component, nucleus molecular_function, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB:P83916 ADO ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0047800=GO_REF:0000003, GO:0046872=GO_REF:0000037} Q96SZ5 2-aminoethanethiol dioxygenase protein 20130413 {GO:0005739=IEA, GO:0047800=IEA, GO:0046872=IEA} mitochondrion cysteamine dioxygenase activity, metal ion binding Human Ensembl:ENSMUSP00000075107 ADORA1 IntAct UniProtKB {GO:0005515=PMID:16481441, GO:0006909=PMID:8360491, GO:0001659=GO_REF:0000019, GO:0043268=GO_REF:0000019, GO:0060087=GO_REF:0000019, GO:0046888=GO_REF:0000019, GO:0048167=GO_REF:0000019, GO:0006612=GO_REF:0000019, GO:0045211=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0030673=GO_REF:0000019, GO:0045822=GO_REF:0000019, GO:0048786=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0051967=GO_REF:0000019, GO:0045741=GO_REF:0000019, GO:0060079=GO_REF:0000019, GO:0014069=GO_REF:0000019, GO:0031683=GO_REF:0000019, GO:0002674=GO_REF:0000019, GO:0016042=GO_REF:0000019, GO:0001609=GO_REF:0000002, GO:0042734=GO_REF:0000019, GO:0005887=PMID:1530647, GO:0001883=GO_REF:0000019, GO:0035814=GO_REF:0000019, GO:0032229=GO_REF:0000019, GO:0055118=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0050995=GO_REF:0000019, GO:0005886=Reactome:REACT_22289, GO:0005783=GO_REF:0000019, GO:0014050=GO_REF:0000019, GO:0007267=PMID:7818494, GO:0045776=GO_REF:0000019, GO:0045777=GO_REF:0000019, GO:0007193=GO_REF:0000019, GO:0070256=GO_REF:0000019, GO:0032279=GO_REF:0000019, GO:0016323=GO_REF:0000019, GO:0004629=GO_REF:0000019, GO:0000186=GO_REF:0000019, GO:0002087=GO_REF:0000019, GO:0006954=PMID:8360491, GO:0043195=GO_REF:0000019, GO:0045908=GO_REF:0000019, GO:0050965=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0001664=GO_REF:0000019, GO:0002793=GO_REF:0000019, GO:0035307=GO_REF:0000019, GO:0032900=GO_REF:0000019, GO:0097190=PMID:7818494, GO:0007399=PMID:8450977, GO:0012505=GO_REF:0000019, GO:0007165=PMID:1530647, GO:0032795=GO_REF:0000019, GO:0042323=GO_REF:0000019, GO:0032244=GO_REF:0000019, GO:0050890=GO_REF:0000019, GO:0003093=GO_REF:0000019, GO:0002686=GO_REF:0000019} P30542 Adenosine receptor A1 protein 20130415 {GO:0005515=IPI, GO:0006909=TAS, GO:0001659=IEA, GO:0043268=IEA, GO:0060087=IEA, GO:0046888=IEA, GO:0048167=IEA, GO:0006612=IEA, GO:0045211=IEA, GO:0043025=IEA, GO:0030673=IEA, GO:0045822=IEA, GO:0048786=IEA, GO:0046982=IEA, GO:0051967=IEA, GO:0045741=IEA, GO:0060079=IEA, GO:0014069=IEA, GO:0031683=IEA, GO:0002674=IEA, GO:0016042=IEA, GO:0001609=IEA, GO:0042734=IEA, GO:0005887=TAS, GO:0001883=IEA, GO:0035814=IEA, GO:0032229=IEA, GO:0055118=IEA, GO:0008285=IEA, GO:0050995=IEA, GO:0005886=TAS, GO:0005783=IEA, GO:0014050=IEA, GO:0007267=TAS, GO:0045776=IEA, GO:0045777=IEA, GO:0007193=IEA, GO:0070256=IEA, GO:0032279=IEA, GO:0016323=IEA, GO:0004629=IEA, GO:0000186=IEA, GO:0002087=IEA, GO:0006954=TAS, GO:0043195=IEA, GO:0045908=IEA, GO:0050965=IEA, GO:0001666=IEA, GO:0043066=IEA, GO:0001664=IEA, GO:0002793=IEA, GO:0035307=IEA, GO:0032900=IEA, GO:0097190=TAS, GO:0007399=TAS, GO:0012505=IEA, GO:0007165=TAS, GO:0032795=IEA, GO:0042323=IEA, GO:0032244=IEA, GO:0050890=IEA, GO:0003093=IEA, GO:0002686=IEA} activation of MAPKK activity, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, apoptotic signaling pathway, cell-cell signaling, cognition, detection of temperature stimulus involved in sensory perception of pain, inflammatory response, lipid catabolic process, negative regulation of acute inflammatory response, negative regulation of apoptotic process, negative regulation of blood pressure, negative regulation of cardiac muscle contraction, negative regulation of cell proliferation, negative regulation of circadian sleep/wake cycle, non-REM sleep, negative regulation of glutamate secretion, negative regulation of heart contraction, negative regulation of hormone secretion, negative regulation of leukocyte migration, negative regulation of lipid catabolic process, negative regulation of mucus secretion, negative regulation of neurotrophin production, negative regulation of renal sodium excretion, negative regulation of synaptic transmission, GABAergic, negative regulation of synaptic transmission, glutamatergic, negative regulation of vasodilation, nervous system development, phagocytosis, positive regulation of blood pressure, positive regulation of epidermal growth factor-activated receptor activity, positive regulation of nucleoside transport, positive regulation of peptide secretion, positive regulation of potassium ion transport, positive regulation of protein dephosphorylation, protein targeting to membrane, regulation of excitatory postsynaptic membrane potential, regulation of glomerular filtration, regulation of respiratory gaseous exchange by neurological system process, regulation of synaptic plasticity, relaxation of vascular smooth muscle, response to hypoxia, signal transduction, temperature homeostasis asymmetric synapse, axolemma, basolateral plasma membrane, endomembrane system, endoplasmic reticulum, integral to plasma membrane, neuronal cell body, plasma membrane, postsynaptic density, postsynaptic membrane, presynaptic active zone, presynaptic membrane, terminal bouton G-protein beta/gamma-subunit complex binding, G-protein coupled adenosine receptor activity, G-protein coupled receptor binding, heterotrimeric G-protein binding, phospholipase C activity, protein binding, protein heterodimerization activity, purine nucleoside binding Human UniProtKB:P29274 ADORA2A IntAct UniProtKB {GO:0006909=PMID:8360491, GO:0005515=PMID:19632986, GO:0046636=GO_REF:0000019, GO:0008015=PMID:9262401, GO:0043524=GO_REF:0000019, GO:0048167=GO_REF:0000019, GO:0045211=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0051924=GO_REF:0000019, GO:0030673=GO_REF:0000019, GO:0014061=GO_REF:0000019, GO:0048786=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0060134=GO_REF:0000019, GO:0051968=GO_REF:0000019, GO:0060079=GO_REF:0000019, GO:0014069=GO_REF:0000019, GO:0007417=PMID:10945659, GO:0032230=GO_REF:0000019, GO:0007271=GO_REF:0000019, GO:0001609=GO_REF:0000019, GO:0042734=GO_REF:0000019, GO:0060080=GO_REF:0000019, GO:0005887=PMID:8794889, GO:0051393=GO_REF:0000019, GO:0035815=GO_REF:0000019, GO:0007188=PMID:10899090, GO:0007189=GO_REF:0000019, GO:0019899=PMID:16339847, GO:0035810=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0005886=Reactome:REACT_22268, GO:2001235=GO_REF:0000019, GO:0030819=GO_REF:0000019, GO:0007267=PMID:7818494, GO:0050714=GO_REF:0000019, GO:0014057=GO_REF:0000019, GO:0048143=GO_REF:0000019, GO:0007205=GO_REF:0000019, GO:0032279=GO_REF:0000019, GO:0014049=GO_REF:0000019, GO:0007190=Reactome:REACT_11046, GO:0006954=PMID:8360491, GO:0031000=GO_REF:0000019, GO:0040013=GO_REF:0000019, GO:0042311=GO_REF:0000019, GO:0001963=GO_REF:0000019, GO:0006171=PMID:10899090, GO:0007626=GO_REF:0000019, GO:0043154=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0006355=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0035249=GO_REF:0000019, GO:0051881=GO_REF:0000019, GO:0006915=PMID:7818494, GO:0012505=GO_REF:0000019, GO:0006968=PMID:10051547, GO:0001975=GO_REF:0000019, GO:0031802=GO_REF:0000019, GO:0016020=PMID:10051547, GO:0007596=PMID:10899090, GO:0048812=GO_REF:0000019, GO:0050728=GO_REF:0000019, GO:0044446=PMID:16339847, GO:0042755=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0006469=GO_REF:0000019, GO:0007169=Reactome:REACT_11064, GO:0007600=PMID:9262401, GO:0043116=GO_REF:0000019} P29274 Adenosine receptor A2a protein 20130415 {GO:0006909=TAS, GO:0005515=IPI, GO:0046636=IEA, GO:0008015=TAS, GO:0043524=IEA, GO:0048167=IEA, GO:0045211=IEA, GO:0043025=IEA, GO:0051924=IEA, GO:0030673=IEA, GO:0014061=IEA, GO:0048786=IEA, GO:0046982=IEA, GO:0060134=IEA, GO:0051968=IEA, GO:0060079=IEA, GO:0014069=IEA, GO:0007417=TAS, GO:0032230=IEA, GO:0007271=IEA, GO:0001609=IEA, GO:0042734=IEA, GO:0060080=IEA, GO:0005887=TAS, GO:0051393=IEA, GO:0035815=IEA, GO:0007188=TAS, GO:0007189=IEA, GO:0019899=IPI, GO:0035810=IEA, GO:0008285=IEA, GO:0005886=TAS, GO:2001235=IEA, GO:0030819=IEA, GO:0007267=TAS, GO:0050714=IEA, GO:0014057=IEA, GO:0048143=IEA, GO:0007205=IEA, GO:0032279=IEA, GO:0014049=IEA, GO:0007190=TAS, GO:0006954=TAS, GO:0031000=IEA, GO:0040013=IEA, GO:0042311=IEA, GO:0001963=IEA, GO:0006171=TAS, GO:0007626=IEA, GO:0043154=IEA, GO:0048011=TAS, GO:0006355=IEA, GO:0042493=IEA, GO:0035249=IEA, GO:0051881=IEA, GO:0006915=TAS, GO:0012505=IEA, GO:0006968=TAS, GO:0001975=IEA, GO:0031802=IEA, GO:0016020=TAS, GO:0007596=TAS, GO:0048812=IEA, GO:0050728=IEA, GO:0044446=IDA, GO:0042755=IEA, GO:0016021=IEA, GO:0006469=IEA, GO:0007169=TAS, GO:0007600=TAS, GO:0043116=IEA} activation of adenylate cyclase activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, apoptotic process, astrocyte activation, blood circulation, blood coagulation, cAMP biosynthetic process, cell-cell signaling, cellular defense response, central nervous system development, eating behavior, inflammatory response, locomotory behavior, negative regulation of alpha-beta T cell activation, negative regulation of cell proliferation, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of inflammatory response, negative regulation of locomotion, negative regulation of neuron apoptotic process, negative regulation of protein kinase activity, negative regulation of vascular permeability, neuron projection morphogenesis, neurotrophin TRK receptor signaling pathway, phagocytosis, positive regulation of acetylcholine secretion, positive regulation of apoptotic signaling pathway, positive regulation of cAMP biosynthetic process, positive regulation of glutamate secretion, positive regulation of protein secretion, positive regulation of renal sodium excretion, positive regulation of synaptic transmission, GABAergic, positive regulation of synaptic transmission, glutamatergic, positive regulation of urine volume, prepulse inhibition, protein kinase C-activating G-protein coupled receptor signaling pathway, regulation of calcium ion transport, regulation of excitatory postsynaptic membrane potential, regulation of inhibitory postsynaptic membrane potential, regulation of mitochondrial membrane potential, regulation of norepinephrine secretion, regulation of synaptic plasticity, regulation of transcription, DNA-dependent, response to amphetamine, response to caffeine, response to drug, sensory perception, synaptic transmission, cholinergic, synaptic transmission, dopaminergic, synaptic transmission, glutamatergic, transmembrane receptor protein tyrosine kinase signaling pathway, vasodilation asymmetric synapse, axolemma, endomembrane system, integral to membrane, integral to plasma membrane, intracellular organelle part, membrane, neuronal cell body, plasma membrane, postsynaptic density, postsynaptic membrane, presynaptic active zone, presynaptic membrane G-protein coupled adenosine receptor activity, alpha-actinin binding, enzyme binding, protein binding, protein heterodimerization activity, type 5 metabotropic glutamate receptor binding Human UniProtKB:P14416 ADORA2B Reactome UniProtKB {GO:0032755=GO_REF:0000019, GO:0007588=PMID:7836474, GO:0005886=Reactome:REACT_22268, GO:0007254=PMID:10101031, GO:0032722=GO_REF:0000019, GO:0010575=GO_REF:0000019, GO:0043306=GO_REF:0000019, GO:0060087=GO_REF:0000019, GO:0007190=PMID:8022409, GO:0001609=GO_REF:0000002, GO:0000187=PMID:10101031, GO:0006968=PMID:10101031, GO:0007186=PMID:7558011, GO:0005887=PMID:7558011, GO:0031668=GO_REF:0000019, GO:0030828=GO_REF:0000019, GO:0031284=GO_REF:0000019, GO:0007189=GO_REF:0000019, GO:0002882=GO_REF:0000019} P29275 Adenosine receptor A2b protein 20090427 {GO:0032755=IEA, GO:0007588=TAS, GO:0005886=TAS, GO:0007254=TAS, GO:0032722=IEA, GO:0010575=IEA, GO:0043306=IEA, GO:0060087=IEA, GO:0007190=TAS, GO:0001609=IEA, GO:0000187=TAS, GO:0006968=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0031668=IEA, GO:0030828=IEA, GO:0031284=IEA, GO:0007189=IEA, GO:0002882=IEA} G-protein coupled receptor signaling pathway, JNK cascade, activation of MAPK activity, activation of adenylate cyclase activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, cellular defense response, cellular response to extracellular stimulus, excretion, positive regulation of cGMP biosynthetic process, positive regulation of chemokine production, positive regulation of chronic inflammatory response to non-antigenic stimulus, positive regulation of guanylate cyclase activity, positive regulation of interleukin-6 production, positive regulation of mast cell degranulation, positive regulation vascular endothelial growth factor production, relaxation of vascular smooth muscle integral to plasma membrane, plasma membrane G-protein coupled adenosine receptor activity Human ADORA3 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0008016=PMID:9837869, GO:0009611=PMID:9837869, GO:0014068=GO_REF:0000019, GO:0043306=GO_REF:0000019, GO:0050850=GO_REF:0000019, GO:0070257=GO_REF:0000019, GO:0001609=GO_REF:0000019, GO:0007165=PMID:9380026, GO:0007190=PMID:9380026, GO:0006954=PMID:9164961, GO:0002553=GO_REF:0000019, GO:0005887=GO_REF:0000019, GO:0002687=GO_REF:0000019, GO:0050729=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q6P2N6 Protein ADORA3, isoform 3 protein 20130413 {GO:0005886=IEA, GO:0008016=TAS, GO:0009611=TAS, GO:0014068=IEA, GO:0043306=IEA, GO:0050850=IEA, GO:0070257=IEA, GO:0001609=IEA, GO:0007165=TAS, GO:0007190=TAS, GO:0006954=TAS, GO:0002553=IEA, GO:0005887=IEA, GO:0002687=IEA, GO:0050729=IEA, GO:0016021=IEA} activation of adenylate cyclase activity, histamine secretion by mast cell, inflammatory response, positive regulation of calcium-mediated signaling, positive regulation of inflammatory response, positive regulation of leukocyte migration, positive regulation of mast cell degranulation, positive regulation of mucus secretion, positive regulation of phosphatidylinositol 3-kinase cascade, regulation of heart contraction, response to wounding, signal transduction integral to membrane, integral to plasma membrane, plasma membrane G-protein coupled adenosine receptor activity Human UniProtKB-SubCell:SL-0039 ADPGK UniPathway UniProtKB {GO:0043843=GO_REF:0000003, GO:0016301=GO_REF:0000038, GO:0005975=GO_REF:0000002, GO:0016773=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0006096=GO_REF:0000041, GO:0046872=GO_REF:0000037} Q9BRR6 ADP-dependent glucokinase protein 20130413 {GO:0043843=IEA, GO:0016301=IEA, GO:0005975=IEA, GO:0016773=IEA, GO:0005576=IEA, GO:0006096=IEA, GO:0046872=IEA} carbohydrate metabolic process, glycolysis extracellular region ADP-specific glucokinase activity, kinase activity, metal ion binding, phosphotransferase activity, alcohol group as acceptor Human UniPathway:UPA00109 ADPRH UniProtKB UniProtKB {GO:0000287=GO_REF:0000002, GO:0003875=PMID:8349667, GO:0051725=GO_REF:0000002, GO:0006464=PMID:8349667} P54922 Protein ADP-ribosylarginine hydrolase protein 20080311 {GO:0000287=IEA, GO:0003875=IMP, GO:0051725=IEA, GO:0006464=IMP} cellular protein modification process, protein de-ADP-ribosylation ADP-ribosylarginine hydrolase activity, magnesium ion binding Human ADPRHL2 HPA UniProtKB {GO:0005759=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0004649=GO_REF:0000003, GO:0005634=GO_REF:0000052, GO:0046872=GO_REF:0000037} Q9NX46 Poly(ADP-ribose) glycohydrolase ARH3 protein 20101115 {GO:0005759=IEA, GO:0005730=IDA, GO:0004649=IEA, GO:0005634=IDA, GO:0046872=IEA} mitochondrial matrix, nucleolus, nucleus metal ion binding, poly(ADP-ribose) glycohydrolase activity NOT Human ADRA1A BHF-UCL UniProtKB {GO:0030018=GO_REF:0000019, GO:0060402=GO_REF:0000024, GO:0008285=PMID:10860850, GO:0005886=Reactome:REACT_22436, GO:0035024=GO_REF:0000024, GO:0007267=PMID:8396931, GO:0007200=GO_REF:0000019, GO:0005634=PMID:22120526, GO:0007202=GO_REF:0000024, GO:0007204=GO_REF:0000024, GO:0007243=PMID:10671514, GO:0007512=GO_REF:0000019, GO:0006939=PMID:8183249, GO:0003084=GO_REF:0000019, GO:0001985=GO_REF:0000019, GO:0045907=GO_REF:0000024, GO:0090037=GO_REF:0000024, GO:0060452=GO_REF:0000024, GO:0035265=GO_REF:0000019, GO:0045987=GO_REF:0000019, GO:0045760=GO_REF:0000024, GO:0009725=GO_REF:0000024, GO:0070374=GO_REF:0000024, GO:0031965=PMID:22120526, GO:0004937=GO_REF:0000024, GO:0046982=PMID:22120526, GO:0042493=GO_REF:0000024, GO:0007568=GO_REF:0000024, GO:0006950=GO_REF:0000024, GO:0097195=GO_REF:0000019, GO:0030315=GO_REF:0000019, GO:0006915=PMID:10671514, GO:0060073=GO_REF:0000019, GO:0001996=GO_REF:0000019, GO:0007165=PMID:8396931, GO:0001994=GO_REF:0000019, GO:0007186=PMID:10860850, GO:0005887=PMID:8396931, GO:0001997=GO_REF:0000019, GO:0032229=GO_REF:0000024, GO:0016049=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0043410=PMID:22120526} P35348 Alpha-1A adrenergic receptor protein 20100202 {GO:0030018=IEA, GO:0060402=ISS, GO:0008285=TAS, GO:0005886=TAS, GO:0035024=ISS, GO:0007267=TAS, GO:0007200=IEA, GO:0005634=IDA, GO:0007202=ISS, GO:0007204=ISS, GO:0007243=TAS, GO:0007512=IEA, GO:0006939=TAS, GO:0003084=IEA, GO:0001985=IEA, GO:0045907=ISS, GO:0090037=ISS, GO:0060452=ISS, GO:0035265=IEA, GO:0045987=IEA, GO:0045760=ISS, GO:0009725=ISS, GO:0070374=ISS, GO:0031965=IDA, GO:0004937=ISS, GO:0046982=IDA, GO:0042493=ISS, GO:0007568=ISS, GO:0006950=ISS, GO:0097195=IEA, GO:0030315=IEA, GO:0006915=TAS, GO:0060073=IEA, GO:0001996=IEA, GO:0007165=TAS, GO:0001994=IEA, GO:0007186=TAS, GO:0005887=TAS, GO:0001997=IEA, GO:0032229=ISS, GO:0016049=IEA, GO:0016021=IEA, GO:0043410=IDA} G-protein coupled receptor signaling pathway, activation of phospholipase C activity, adult heart development, aging, apoptotic process, calcium ion transport into cytosol, cell growth, cell-cell signaling, elevation of cytosolic calcium ion concentration, intracellular protein kinase cascade, micturition, negative regulation of Rho protein signal transduction, negative regulation of cell proliferation, negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure, negative regulation of synaptic transmission, GABAergic, norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure, organ growth, phospholipase C-activating G-protein coupled receptor signaling pathway, pilomotor reflex, positive regulation of ERK1 and ERK2 cascade, positive regulation of MAPK cascade, positive regulation of action potential, positive regulation of cardiac muscle contraction, positive regulation of heart rate by epinephrine-norepinephrine, positive regulation of protein kinase C signaling cascade, positive regulation of smooth muscle contraction, positive regulation of systemic arterial blood pressure, positive regulation of the force of heart contraction by epinephrine-norepinephrine, positive regulation of vasoconstriction, response to drug, response to hormone stimulus, response to stress, signal transduction, smooth muscle contraction T-tubule, Z disc, integral to membrane, integral to plasma membrane, nuclear membrane, nucleus, plasma membrane alpha1-adrenergic receptor activity, protein heterodimerization activity Human UniProtKB:P43140 ADRA1B Reactome UniProtKB {GO:0005886=Reactome:REACT_22436, GO:0008283=PMID:10820200, GO:0007267=PMID:1328250, GO:0048148=GO_REF:0000019, GO:0005634=PMID:22120526, GO:0007243=PMID:10820200, GO:0007512=GO_REF:0000019, GO:0001987=GO_REF:0000019, GO:0035265=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0004937=GO_REF:0000019, GO:0031965=PMID:22120526, GO:0046982=PMID:22120526, GO:0043278=GO_REF:0000019, GO:0007275=PMID:10820200, GO:0042593=GO_REF:0000019, GO:0001996=GO_REF:0000019, GO:0001975=GO_REF:0000019, GO:0045818=GO_REF:0000019, GO:0045819=GO_REF:0000019, GO:0007186=PMID:2154750, GO:0005887=PMID:1328250, GO:0001974=GO_REF:0000019, GO:0008542=GO_REF:0000019, GO:0001997=GO_REF:0000019, GO:0016049=GO_REF:0000019, GO:0007188=PMID:10820200, GO:0043410=PMID:22120526} P35368 Alpha-1B adrenergic receptor protein 20090210 {GO:0005886=TAS, GO:0008283=TAS, GO:0007267=TAS, GO:0048148=IEA, GO:0005634=IDA, GO:0007243=TAS, GO:0007512=IEA, GO:0001987=IEA, GO:0035265=IEA, GO:0007626=IEA, GO:0004937=IEA, GO:0031965=IDA, GO:0046982=IDA, GO:0043278=IEA, GO:0007275=TAS, GO:0042593=IEA, GO:0001996=IEA, GO:0001975=IEA, GO:0045818=IEA, GO:0045819=IEA, GO:0007186=TAS, GO:0005887=TAS, GO:0001974=IEA, GO:0008542=IEA, GO:0001997=IEA, GO:0016049=IEA, GO:0007188=TAS, GO:0043410=IDA} G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, adult heart development, behavioral response to cocaine, blood vessel remodeling, cell growth, cell proliferation, cell-cell signaling, glucose homeostasis, intracellular protein kinase cascade, locomotory behavior, multicellular organismal development, negative regulation of glycogen catabolic process, organ growth, positive regulation of MAPK cascade, positive regulation of glycogen catabolic process, positive regulation of heart rate by epinephrine-norepinephrine, positive regulation of the force of heart contraction by epinephrine-norepinephrine, response to amphetamine, response to morphine, vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure, visual learning integral to plasma membrane, nuclear membrane, nucleus, plasma membrane alpha1-adrenergic receptor activity, protein heterodimerization activity Human ADRA1D Reactome UniProtKB {GO:0008284=PMID:10860850, GO:0004937=GO_REF:0000019, GO:0001994=GO_REF:0000019, GO:0005886=Reactome:REACT_22436, GO:0007186=PMID:1656955, GO:0001986=GO_REF:0000019, GO:0008283=PMID:10820200, GO:0005887=PMID:7746284, GO:0007267=PMID:1656955, GO:0007275=PMID:10820200, GO:0007188=PMID:10820200, GO:0006259=PMID:10969806} P25100 Alpha-1D adrenergic receptor protein 20090210 {GO:0008284=TAS, GO:0004937=IEA, GO:0001994=IEA, GO:0005886=TAS, GO:0007186=TAS, GO:0001986=IEA, GO:0008283=TAS, GO:0005887=TAS, GO:0007267=TAS, GO:0007275=TAS, GO:0007188=TAS, GO:0006259=TAS} DNA metabolic process, G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, cell proliferation, cell-cell signaling, multicellular organismal development, negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure, norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure, positive regulation of cell proliferation integral to plasma membrane, plasma membrane alpha1-adrenergic receptor activity Human ADRA2A BHF-UCL UniProtKB {GO:0005515=PMID:16531006, GO:0032811=PMID:16531006, GO:0045202=GO_REF:0000019, GO:0043268=PMID:1354394, GO:0001819=PMID:17655843, GO:0031696=PMID:16605244, GO:0042803=PMID:16605244, GO:0042596=GO_REF:0000019, GO:0070473=GO_REF:0000019, GO:0051926=GO_REF:0000024, GO:0046676=PMID:10952463, GO:0002526=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:0030335=PMID:17655843, GO:0046982=GO_REF:0000024, GO:0019901=PMID:15653687, GO:0045741=PMID:17655843, GO:0035625=PMID:17215105, GO:0030168=Reactome:REACT_798, GO:0010700=PMID:19477270, GO:0004938=PMID:10948191, GO:0043235=PMID:10948191, GO:0031692=GO_REF:0000024, GO:0007186=PMID:19965390, GO:0005887=PMID:10948191, GO:0071878=GO_REF:0000024, GO:0008284=PMID:10896916, GO:0051044=PMID:17655843, GO:0050995=PMID:10948198, GO:0030036=PMID:9624180, GO:0005886=Reactome:REACT_22380, GO:1901020=PMID:1354394, GO:0090303=PMID:17655843, GO:0030818=PMID:16531006, GO:0006928=PMID:9624180, GO:0031996=PMID:19477270, GO:0051379=PMID:10948191, GO:0007265=PMID:8226727, GO:0044281=Reactome:REACT_111217, GO:0007266=PMID:9624180, GO:0007194=PMID:1354394, GO:0032870=PMID:10948198, GO:0032147=PMID:15653687, GO:0051380=PMID:2823383, GO:0016323=PMID:17655843, GO:0005737=PMID:19477270, GO:0043406=PMID:19477270, GO:0045909=GO_REF:0000019, GO:0032148=PMID:17215105, GO:0071881=PMID:10948191, GO:0071882=PMID:10948191, GO:0071883=PMID:10948191, GO:0042593=PMID:10952463, GO:0006260=GO_REF:0000019, GO:0007165=PMID:2823383, GO:0050892=PMID:17655843, GO:0032795=PMID:10948191, GO:0006112=Reactome:REACT_1505, GO:0045955=PMID:19965390, GO:0050796=Reactome:REACT_18325, GO:0007596=Reactome:REACT_604, GO:0050955=GO_REF:0000019, GO:0061179=PMID:19965390} P08913 Alpha-2A adrenergic receptor protein 20120917 {GO:0005515=IPI, GO:0032811=NAS, GO:0045202=IEA, GO:0043268=ISS, GO:0001819=IDA, GO:0031696=IPI, GO:0042803=IDA, GO:0042596=IEA, GO:0070473=IEA, GO:0051926=ISS, GO:0046676=IMP, GO:0002526=IEA, GO:0007565=IEA, GO:0030335=IMP, GO:0046982=ISS, GO:0019901=IPI, GO:0045741=IDA, GO:0035625=IDA, GO:0030168=TAS, GO:0010700=TAS, GO:0004938=IDA, GO:0043235=IDA, GO:0031692=ISS, GO:0007186=ISS, GO:0005887=IDA, GO:0071878=ISS, GO:0008284=TAS, GO:0051044=IDA, GO:0050995=IGI, GO:0030036=TAS, GO:0005886=TAS, GO:1901020=ISS, GO:0090303=IMP, GO:0030818=IDA, GO:0006928=TAS, GO:0031996=IPI, GO:0051379=IDA, GO:0007265=TAS, GO:0044281=TAS, GO:0007266=TAS, GO:0007194=ISS, GO:0032870=IGI, GO:0032147=IDA, GO:0051380=IDA, GO:0016323=TAS, GO:0005737=IDA, GO:0043406=IDA, GO:0045909=IEA, GO:0032148=IDA, GO:0071881=IDA, GO:0071882=IDA, GO:0071883=IDA, GO:0042593=IMP, GO:0006260=IEA, GO:0007165=TAS, GO:0050892=TAS, GO:0032795=IDA, GO:0006112=TAS, GO:0045955=IC, GO:0050796=TAS, GO:0007596=TAS, GO:0050955=IEA, GO:0061179=IMP} DNA replication, G-protein coupled receptor signaling pathway, Ras protein signal transduction, Rho protein signal transduction, actin cytoskeleton organization, activation of MAPK activity by adrenergic receptor signaling pathway, activation of protein kinase B activity, activation of protein kinase activity, acute inflammatory response, adenylate cyclase-inhibiting adrenergic receptor signaling pathway, blood coagulation, cellular component movement, cellular response to hormone stimulus, energy reserve metabolic process, epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway, fear response, female pregnancy, glucose homeostasis, intestinal absorption, negative regulation of adenylate cyclase activity, negative regulation of adrenergic receptor signaling pathway, negative regulation of cAMP biosynthetic process, negative regulation of calcium ion transmembrane transporter activity, negative regulation of calcium ion transport, negative regulation of calcium ion-dependent exocytosis, negative regulation of epinephrine secretion, negative regulation of insulin secretion, negative regulation of insulin secretion involved in cellular response to glucose stimulus, negative regulation of lipid catabolic process, negative regulation of norepinephrine secretion, negative regulation of uterine smooth muscle contraction, phospholipase C-activating adrenergic receptor signaling pathway, platelet activation, positive regulation of MAP kinase activity, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of cytokine production, positive regulation of epidermal growth factor-activated receptor activity, positive regulation of membrane protein ectodomain proteolysis, positive regulation of potassium ion transport, positive regulation of vasodilation, positive regulation of wound healing, regulation of insulin secretion, signal transduction, small molecule metabolic process, thermoception basolateral plasma membrane, cytoplasm, integral to plasma membrane, plasma membrane, receptor complex, synapse alpha-1B adrenergic receptor binding, alpha-2C adrenergic receptor binding, alpha2-adrenergic receptor activity, epinephrine binding, heterotrimeric G-protein binding, norepinephrine binding, protein binding, protein heterodimerization activity, protein homodimerization activity, protein kinase binding, thioesterase binding Human UniProtKB:P18871 ADRA2B BHF-UCL UniProtKB {GO:0005515=PMID:16531006, GO:0007565=GO_REF:0000019, GO:0032811=PMID:16531006, GO:0005886=Reactome:REACT_22380, GO:0035625=PMID:17215105, GO:0007267=PMID:2164221, GO:0030168=Reactome:REACT_798, GO:0051379=PMID:17215105, GO:0001525=GO_REF:0000019, GO:0010700=PMID:19477270, GO:0045777=GO_REF:0000019, GO:0004938=PMID:17215105, GO:0070474=GO_REF:0000019, GO:0007186=PMID:2164221, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:2164221, GO:0000165=GO_REF:0000019, GO:0045666=PMID:17215105, GO:0003056=GO_REF:0000019, GO:0032148=PMID:17215105, GO:0071883=PMID:17215105} P18089 Alpha-2B adrenergic receptor protein 20100624 {GO:0005515=IPI, GO:0007565=IEA, GO:0032811=NAS, GO:0005886=TAS, GO:0035625=IDA, GO:0007267=TAS, GO:0030168=TAS, GO:0051379=IDA, GO:0001525=IEA, GO:0010700=TAS, GO:0045777=IEA, GO:0004938=IDA, GO:0070474=IEA, GO:0007186=TAS, GO:0007596=TAS, GO:0005887=TAS, GO:0000165=IEA, GO:0045666=IDA, GO:0003056=IEA, GO:0032148=IDA, GO:0071883=IDA} G-protein coupled receptor signaling pathway, MAPK cascade, activation of MAPK activity by adrenergic receptor signaling pathway, activation of protein kinase B activity, angiogenesis, blood coagulation, cell-cell signaling, epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway, female pregnancy, negative regulation of epinephrine secretion, negative regulation of norepinephrine secretion, platelet activation, positive regulation of blood pressure, positive regulation of neuron differentiation, positive regulation of uterine smooth muscle contraction, regulation of vascular smooth muscle contraction integral to plasma membrane, plasma membrane alpha2-adrenergic receptor activity, epinephrine binding, protein binding Human ADRA2C BHF-UCL UniProtKB {GO:0005515=PMID:16531006, GO:0032811=PMID:16531006, GO:0005886=Reactome:REACT_22380, GO:0007267=PMID:9371698, GO:0051379=PMID:17215105, GO:0044281=Reactome:REACT_111217, GO:0031694=PMID:16605244, GO:0042803=PMID:16605244, GO:0005737=PMID:16605244, GO:0045907=GO_REF:0000019, GO:0070473=GO_REF:0000019, GO:0032148=PMID:17215105, GO:0043679=GO_REF:0000019, GO:0071883=PMID:17215105, GO:0007565=GO_REF:0000019, GO:0046982=PMID:16605244, GO:0035625=PMID:17215105, GO:0030168=Reactome:REACT_798, GO:0010700=PMID:19477270, GO:0004938=PMID:17215105, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0007186=PMID:9371698, GO:0045666=PMID:17215105, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:16605244, GO:0016021=GO_REF:0000038, GO:0005768=PMID:10196213, GO:0051930=GO_REF:0000019} P18825 Alpha-2C adrenergic receptor protein 20100624 {GO:0005515=IPI, GO:0032811=NAS, GO:0005886=TAS, GO:0007267=TAS, GO:0051379=IDA, GO:0044281=TAS, GO:0031694=IPI, GO:0042803=IDA, GO:0005737=IDA, GO:0045907=IEA, GO:0070473=IEA, GO:0032148=IDA, GO:0043679=IEA, GO:0071883=IDA, GO:0007565=IEA, GO:0046982=IPI, GO:0035625=IDA, GO:0030168=TAS, GO:0010700=TAS, GO:0004938=IDA, GO:0006112=TAS, GO:0050796=TAS, GO:0007186=TAS, GO:0045666=IDA, GO:0007596=TAS, GO:0005887=IDA, GO:0016021=IEA, GO:0005768=TAS, GO:0051930=IEA} G-protein coupled receptor signaling pathway, activation of MAPK activity by adrenergic receptor signaling pathway, activation of protein kinase B activity, blood coagulation, cell-cell signaling, energy reserve metabolic process, epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway, female pregnancy, negative regulation of epinephrine secretion, negative regulation of norepinephrine secretion, negative regulation of uterine smooth muscle contraction, platelet activation, positive regulation of neuron differentiation, positive regulation of vasoconstriction, regulation of insulin secretion, regulation of sensory perception of pain, small molecule metabolic process axon terminus, cytoplasm, endosome, integral to membrane, integral to plasma membrane, plasma membrane alpha-2A adrenergic receptor binding, alpha2-adrenergic receptor activity, epinephrine binding, protein binding, protein heterodimerization activity, protein homodimerization activity Human ADRB1 BHF-UCL UniProtKB {GO:0005515=PMID:16316992, GO:0005886=Reactome:REACT_22268, GO:0030819=PMID:12529373, GO:0009409=GO_REF:0000019, GO:0002024=GO_REF:0000019, GO:0002025=GO_REF:0000019, GO:0051379=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0007266=GO_REF:0000019, GO:2001259=GO_REF:0000019, GO:0031694=PMID:12529373, GO:0061051=GO_REF:0000019, GO:0007190=PMID:10212248, GO:0031649=GO_REF:0000019, GO:0051380=GO_REF:0000019, GO:0042596=GO_REF:0000019, GO:0003084=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0040015=GO_REF:0000019, GO:0045986=GO_REF:0000019, GO:0008144=GO_REF:0000019, GO:0051924=GO_REF:0000019, GO:0007613=GO_REF:0000019, GO:0086004=GO_REF:0000019, GO:0003061=GO_REF:0000019, GO:0046982=PMID:12529373, GO:0033365=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0055088=GO_REF:0000019, GO:0035240=GO_REF:0000019, GO:0006915=GO_REF:0000019, GO:0004939=PMID:8892658, GO:0030165=PMID:11526121, GO:0019233=GO_REF:0000019, GO:0001996=GO_REF:0000019, GO:0060080=GO_REF:0000019, GO:0046878=GO_REF:0000019, GO:0005887=PMID:10212248, GO:0050873=GO_REF:0000019, GO:0042060=GO_REF:0000019, GO:0035811=GO_REF:0000019, GO:0004940=GO_REF:0000019, GO:0007189=GO_REF:0000019, GO:0005980=GO_REF:0000019} P08588 Beta-1 adrenergic receptor protein 20100628 {GO:0005515=IPI, GO:0005886=TAS, GO:0030819=IDA, GO:0009409=IEA, GO:0002024=IEA, GO:0002025=IEA, GO:0051379=IEA, GO:0005634=IEA, GO:0007266=IEA, GO:2001259=IEA, GO:0031694=IPI, GO:0061051=IEA, GO:0007190=TAS, GO:0031649=IEA, GO:0051380=IEA, GO:0042596=IEA, GO:0003084=IEA, GO:0005737=IEA, GO:0040015=IEA, GO:0045986=IEA, GO:0008144=IEA, GO:0051924=IEA, GO:0007613=IEA, GO:0086004=IEA, GO:0003061=IEA, GO:0046982=IPI, GO:0033365=IEA, GO:0007568=IEA, GO:0055088=IEA, GO:0035240=IEA, GO:0006915=IEA, GO:0004939=TAS, GO:0030165=IPI, GO:0019233=IEA, GO:0001996=IEA, GO:0060080=IEA, GO:0046878=IEA, GO:0005887=TAS, GO:0050873=IEA, GO:0042060=IEA, GO:0035811=IEA, GO:0004940=IEA, GO:0007189=IEA, GO:0005980=IEA} Rho protein signal transduction, activation of adenylate cyclase activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, aging, apoptotic process, brown fat cell differentiation, diet induced thermogenesis, fear response, glycogen catabolic process, heat generation, lipid homeostasis, memory, negative regulation of multicellular organism growth, negative regulation of smooth muscle contraction, negative regulation of urine volume, positive regulation of cAMP biosynthetic process, positive regulation of cation channel activity, positive regulation of cell growth involved in cardiac muscle cell development, positive regulation of heart rate by epinephrine-norepinephrine, positive regulation of saliva secretion, positive regulation of systemic arterial blood pressure, positive regulation of the force of heart contraction by norepinephrine, protein localization to organelle, regulation of calcium ion transport, regulation of cardiac muscle cell contraction, regulation of inhibitory postsynaptic membrane potential, response to cold, sensory perception of pain, vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure, wound healing cytoplasm, integral to plasma membrane, nucleus, plasma membrane PDZ domain binding, alpha-2A adrenergic receptor binding, beta-adrenergic receptor activity, beta1-adrenergic receptor activity, dopamine binding, drug binding, epinephrine binding, norepinephrine binding, protein binding, protein heterodimerization activity Human UniProtKB:P18871 ADRB2 BHF-UCL UniProtKB {GO:0005515=PMID:15123695, GO:0005886=Reactome:REACT_22268, GO:0045453=GO_REF:0000019, GO:0004941=PMID:15123695, GO:0009409=GO_REF:0000019, GO:0002024=GO_REF:0000019, GO:0015459=PMID:12297500, GO:0002025=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0005764=PMID:9507004, GO:0042803=PMID:15123695, GO:0051380=PMID:15123695, GO:0031649=GO_REF:0000019, GO:0007190=PMID:15123695, GO:0016324=GO_REF:0000019, GO:0007171=PMID:10734107, GO:0040015=GO_REF:0000019, GO:0045986=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0031398=PMID:19372219, GO:0030501=GO_REF:0000019, GO:0008179=GO_REF:0000019, GO:0008333=PMID:9507004, GO:0006898=PMID:15123695, GO:0002032=PMID:15123695, GO:0043235=PMID:15123695, GO:0005887=PMID:12297500, GO:0050873=GO_REF:0000019, GO:0002028=GO_REF:0000019, GO:0007188=PMID:2823249, GO:0007189=GO_REF:0000019, GO:0043410=PMID:15123695, GO:0007166=PMID:1371121, GO:0005768=PMID:10734107} P07550 Beta-2 adrenergic receptor protein 20120316 {GO:0005515=IPI, GO:0005886=TAS, GO:0045453=IEA, GO:0004941=IDA, GO:0009409=IEA, GO:0002024=IEA, GO:0015459=IDA, GO:0002025=IEA, GO:0005634=IEA, GO:0005764=TAS, GO:0042803=IDA, GO:0051380=IDA, GO:0031649=IEA, GO:0007190=IDA, GO:0016324=IEA, GO:0007171=TAS, GO:0040015=IEA, GO:0045986=IEA, GO:0045944=IEA, GO:0031398=IMP, GO:0030501=IEA, GO:0008179=IEA, GO:0008333=TAS, GO:0006898=IDA, GO:0002032=IDA, GO:0043235=IDA, GO:0005887=IDA, GO:0050873=IEA, GO:0002028=IEA, GO:0007188=TAS, GO:0007189=IEA, GO:0043410=IDA, GO:0007166=TAS, GO:0005768=TAS} activation of adenylate cyclase activity, activation of transmembrane receptor protein tyrosine kinase activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, bone resorption, brown fat cell differentiation, cell surface receptor signaling pathway, desensitization of G-protein coupled receptor protein signaling pathway by arrestin, diet induced thermogenesis, endosome to lysosome transport, heat generation, negative regulation of multicellular organism growth, negative regulation of smooth muscle contraction, positive regulation of MAPK cascade, positive regulation of bone mineralization, positive regulation of protein ubiquitination, positive regulation of transcription from RNA polymerase II promoter, receptor-mediated endocytosis, regulation of sodium ion transport, response to cold, vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure apical plasma membrane, endosome, integral to plasma membrane, lysosome, nucleus, plasma membrane, receptor complex adenylate cyclase binding, beta2-adrenergic receptor activity, norepinephrine binding, potassium channel regulator activity, protein binding, protein homodimerization activity Human ADRB3 Reactome UniProtKB {GO:0005515=PMID:15123695, GO:0005886=Reactome:REACT_22268, GO:0009409=GO_REF:0000019, GO:0002024=GO_REF:0000019, GO:0031699=GO_REF:0000019, GO:0002025=GO_REF:0000019, GO:0051379=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0006091=PMID:2570461, GO:0015052=PMID:9892244, GO:0042803=PMID:15123695, GO:0051380=PMID:15123695, GO:0031649=GO_REF:0000019, GO:0007190=PMID:15123695, GO:0040015=GO_REF:0000019, GO:0046677=GO_REF:0000019, GO:0005975=PMID:2570461, GO:0007568=GO_REF:0000019, GO:0004939=PMID:15123695, GO:0006898=PMID:15123695, GO:0002032=PMID:15123695, GO:0043235=PMID:15123695, GO:0006112=PMID:1718744, GO:0005887=PMID:1718744, GO:0007187=PMID:2570461, GO:0050873=GO_REF:0000019, GO:0042755=GO_REF:0000019, GO:0007188=PMID:1718744, GO:0007189=GO_REF:0000019, GO:0043410=PMID:15123695} P13945 Beta-3 adrenergic receptor protein 20090210 {GO:0005515=IPI, GO:0005886=TAS, GO:0009409=IEA, GO:0002024=IEA, GO:0031699=IEA, GO:0002025=IEA, GO:0051379=IEA, GO:0005634=IEA, GO:0006091=TAS, GO:0015052=IMP, GO:0042803=IDA, GO:0051380=IDA, GO:0031649=IEA, GO:0007190=IDA, GO:0040015=IEA, GO:0046677=IEA, GO:0005975=TAS, GO:0007568=IEA, GO:0004939=IDA, GO:0006898=IDA, GO:0002032=IDA, GO:0043235=IDA, GO:0006112=TAS, GO:0005887=TAS, GO:0007187=TAS, GO:0050873=IEA, GO:0042755=IEA, GO:0007188=TAS, GO:0007189=IEA, GO:0043410=IDA} G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, activation of adenylate cyclase activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, aging, brown fat cell differentiation, carbohydrate metabolic process, desensitization of G-protein coupled receptor protein signaling pathway by arrestin, diet induced thermogenesis, eating behavior, energy reserve metabolic process, generation of precursor metabolites and energy, heat generation, negative regulation of multicellular organism growth, positive regulation of MAPK cascade, receptor-mediated endocytosis, response to antibiotic, response to cold, vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure integral to plasma membrane, nucleus, plasma membrane, receptor complex beta-3 adrenergic receptor binding, beta-adrenergic receptor activity, beta3-adrenergic receptor activity, epinephrine binding, norepinephrine binding, protein binding, protein homodimerization activity Human ADRBK1 BHF-UCL UniProtKB {GO:0005515=PMID:17986524, GO:0005886=Reactome:REACT_19213, GO:0038032=GO_REF:0000002, GO:0007202=Reactome:REACT_12079, GO:0060048=PMID:15051637, GO:0031694=GO_REF:0000024, GO:0005829=Reactome:REACT_15534, GO:0031623=PMID:20074556, GO:0007507=GO_REF:0000019, GO:0005737=PMID:17986524, GO:0005543=GO_REF:0000002, GO:0004703=GO_REF:0000024, GO:0007173=Reactome:REACT_9417, GO:0018105=GO_REF:0000024, GO:0018107=GO_REF:0000019, GO:0045988=PMID:15051637, GO:0048011=Reactome:REACT_11061, GO:0003108=PMID:15051637, GO:0007217=PMID:17986524, GO:0007213=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0033605=GO_REF:0000024, GO:0007165=Reactome:REACT_12478, GO:0004672=GO_REF:0000024, GO:0016020=GO_REF:0000024, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0002029=GO_REF:0000024, GO:0047696=GO_REF:0000003, GO:0031755=PMID:19306925} P25098 Beta-adrenergic receptor kinase 1 protein 20080208 {GO:0005515=IPI, GO:0005886=TAS, GO:0038032=IEA, GO:0007202=TAS, GO:0060048=IMP, GO:0031694=ISS, GO:0005829=TAS, GO:0031623=IDA, GO:0007507=IEA, GO:0005737=IDA, GO:0005543=IEA, GO:0004703=ISS, GO:0007173=TAS, GO:0018105=ISS, GO:0018107=IEA, GO:0045988=IMP, GO:0048011=TAS, GO:0003108=IMP, GO:0007217=IDA, GO:0007213=ISS, GO:0005524=IEA, GO:0033605=ISS, GO:0007165=TAS, GO:0004672=ISS, GO:0016020=ISS, GO:0008543=TAS, GO:0045087=TAS, GO:0002029=ISS, GO:0047696=IEA, GO:0031755=IDA} G-protein coupled acetylcholine receptor signaling pathway, activation of phospholipase C activity, cardiac muscle contraction, desensitization of G-protein coupled receptor protein signaling pathway, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, heart development, innate immune response, negative regulation of striated muscle contraction, negative regulation of the force of heart contraction by chemical signal, neurotrophin TRK receptor signaling pathway, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, positive regulation of catecholamine secretion, receptor internalization, signal transduction, tachykinin receptor signaling pathway, termination of G-protein coupled receptor signaling pathway cytoplasm, cytosol, membrane, plasma membrane ATP binding, Edg-2 lysophosphatidic acid receptor binding, G-protein coupled receptor kinase activity, alpha-2A adrenergic receptor binding, beta-adrenergic receptor kinase activity, phospholipid binding, protein binding, protein kinase activity Human UniProtKB:P26817 ADRBK2 PINC UniProtKB {GO:0031623=PMID:20074556, GO:0007165=GO_REF:0000002, GO:0004672=PMID:8427589, GO:0004703=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0047696=GO_REF:0000003, GO:0038032=GO_REF:0000002, GO:0005524=GO_REF:0000037} P35626 Beta-adrenergic receptor kinase 2 protein 20030904 {GO:0031623=IDA, GO:0007165=IEA, GO:0004672=TAS, GO:0004703=IEA, GO:0005543=IEA, GO:0047696=IEA, GO:0038032=IEA, GO:0005524=IEA} receptor internalization, signal transduction, termination of G-protein coupled receptor signaling pathway ATP binding, G-protein coupled receptor kinase activity, beta-adrenergic receptor kinase activity, phospholipid binding, protein kinase activity Human ADRM1 GOC UniProtKB {GO:0000502=PMID:16990800, GO:0006368=PMID:11818576, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0002020=PMID:18922472, GO:0043248=PMID:16990800, GO:0005737=GO_REF:0000052, GO:0016020=PMID:8033103, GO:0005887=PMID:8033103, GO:0061133=PMID:16990800, GO:0010950=PMID:16990800, GO:0070628=PMID:18162577} Q16186 Proteasomal ubiquitin receptor ADRM1 protein 20130413 {GO:0000502=IDA, GO:0006368=IMP, GO:0005886=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0002020=IPI, GO:0043248=IDA, GO:0005737=IDA, GO:0016020=TAS, GO:0005887=TAS, GO:0061133=IDA, GO:0010950=IDA, GO:0070628=IDA} positive regulation of endopeptidase activity, proteasome assembly, transcription elongation from RNA polymerase II promoter cytoplasm, integral to plasma membrane, membrane, nucleolus, nucleus, plasma membrane, proteasome complex endopeptidase activator activity, protease binding, proteasome binding Human ADSL HPA UniProtKB {GO:0001666=GO_REF:0000019, GO:0009168=Reactome:REACT_1776, GO:0051262=PMID:16973378, GO:0007584=GO_REF:0000019, GO:0014850=GO_REF:0000019, GO:0070626=GO_REF:0000003, GO:0055086=Reactome:REACT_1698, GO:0004018=Reactome:REACT_1463, GO:0009152=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0044208=GO_REF:0000041, GO:0005829=Reactome:REACT_1463, GO:0005739=GO_REF:0000019, GO:0009060=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0006167=PMID:11428554, GO:0042594=GO_REF:0000019, GO:0006144=Reactome:REACT_522, GO:0006164=PMID:10888601, GO:0006189=GO_REF:0000041} P30566 Adenylosuccinate lyase protein 20080205 {GO:0001666=IEA, GO:0009168=TAS, GO:0051262=IDA, GO:0007584=IEA, GO:0014850=IEA, GO:0070626=IEA, GO:0055086=TAS, GO:0004018=TAS, GO:0009152=IEA, GO:0044281=TAS, GO:0044208=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0009060=IEA, GO:0005737=IDA, GO:0006167=IDA, GO:0042594=IEA, GO:0006144=TAS, GO:0006164=IC, GO:0006189=IEA} 'de novo' AMP biosynthetic process, 'de novo' IMP biosynthetic process, AMP biosynthetic process, aerobic respiration, nucleobase-containing small molecule metabolic process, protein tetramerization, purine nucleobase metabolic process, purine nucleotide biosynthetic process, purine ribonucleoside monophosphate biosynthetic process, purine ribonucleotide biosynthetic process, response to hypoxia, response to muscle activity, response to nutrient, response to starvation, small molecule metabolic process cytoplasm, cytosol, mitochondrion (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity, N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity Human ADSS HPA UniProtKB {GO:0046040=GO_REF:0000019, GO:0009168=Reactome:REACT_1776, GO:0000287=GO_REF:0000020, GO:0006531=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0004019=PMID:1592113, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0044208=GO_REF:0000041, GO:0005525=PMID:1592113, GO:0014074=GO_REF:0000019, GO:0005829=Reactome:REACT_1719, GO:0006184=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0071257=GO_REF:0000019, GO:0006167=PMID:1592113, GO:0006144=Reactome:REACT_522, GO:0042301=PMID:1592113, GO:0060359=GO_REF:0000019, GO:0002376=PMID:15786719} P30520 Adenylosuccinate synthetase isozyme 2 protein 20101115 {GO:0046040=IEA, GO:0009168=TAS, GO:0000287=IEA, GO:0006531=IEA, GO:0005886=IDA, GO:0004019=NAS, GO:0055086=TAS, GO:0044281=TAS, GO:0044208=IEA, GO:0005525=NAS, GO:0014074=IEA, GO:0005829=TAS, GO:0006184=IEA, GO:0005737=IDA, GO:0071257=IEA, GO:0006167=NAS, GO:0006144=TAS, GO:0042301=NAS, GO:0060359=IEA, GO:0002376=NAS} 'de novo' AMP biosynthetic process, AMP biosynthetic process, GTP catabolic process, IMP metabolic process, aspartate metabolic process, cellular response to electrical stimulus, immune system process, nucleobase-containing small molecule metabolic process, purine nucleobase metabolic process, purine ribonucleoside monophosphate biosynthetic process, response to ammonium ion, response to purine-containing compound, small molecule metabolic process cytoplasm, cytosol, plasma membrane GTP binding, adenylosuccinate synthase activity, magnesium ion binding, phosphate ion binding Human ADSSL1 Reactome UniProtKB {GO:0000287=GO_REF:0000020, GO:0009168=Reactome:REACT_1776, GO:0004019=PMID:15786719, GO:0055086=Reactome:REACT_1698, GO:0044208=GO_REF:0000041, GO:0044281=Reactome:REACT_111217, GO:0005525=PMID:15786719, GO:0005829=Reactome:REACT_1719, GO:0005737=PMID:15786719, GO:0006167=PMID:15786719, GO:0006144=Reactome:REACT_522, GO:0042301=PMID:15786719, GO:0006164=GO_REF:0000002, GO:0002376=PMID:15786719} Q8N142 Adenylosuccinate synthetase isozyme 1 protein 20130213 {GO:0000287=IEA, GO:0009168=TAS, GO:0004019=IDA, GO:0055086=TAS, GO:0044208=IEA, GO:0044281=TAS, GO:0005525=NAS, GO:0005829=TAS, GO:0005737=IDA, GO:0006167=IDA, GO:0006144=TAS, GO:0042301=NAS, GO:0006164=IEA, GO:0002376=NAS} 'de novo' AMP biosynthetic process, AMP biosynthetic process, immune system process, nucleobase-containing small molecule metabolic process, purine nucleobase metabolic process, purine nucleotide biosynthetic process, purine ribonucleoside monophosphate biosynthetic process, small molecule metabolic process cytoplasm, cytosol GTP binding, adenylosuccinate synthase activity, magnesium ion binding, phosphate ion binding Human AEBP1 PINC UniProtKB {GO:0005516=GO_REF:0000037, GO:0003700=PMID:8920928, GO:0003714=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0001501=PMID:8920928, GO:0007517=PMID:9624159, GO:0006508=GO_REF:0000002, GO:0004180=PMID:8920928, GO:0008270=GO_REF:0000002, GO:0007155=GO_REF:0000002, GO:0004181=GO_REF:0000002} Q8IUX7 Adipocyte enhancer-binding protein 1 protein 20090721 {GO:0005516=IEA, GO:0003700=TAS, GO:0003714=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0005737=IEA, GO:0001501=TAS, GO:0007517=TAS, GO:0006508=IEA, GO:0004180=TAS, GO:0008270=IEA, GO:0007155=IEA, GO:0004181=IEA} cell adhesion, muscle organ development, proteolysis, skeletal system development, transcription, DNA-dependent cytoplasm, nucleus DNA binding, calmodulin binding, carboxypeptidase activity, metallocarboxypeptidase activity, sequence-specific DNA binding transcription factor activity, transcription corepressor activity, zinc ion binding Human AEBP2 UniProtKB UniProtKB {GO:0006355=GO_REF:0000019, GO:0035098=PMID:20075857, GO:0003714=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q6ZN18 Zinc finger protein AEBP2 protein 20100127 {GO:0006355=IEA, GO:0035098=IDA, GO:0003714=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0016568=IEA} chromatin modification, regulation of transcription, DNA-dependent, transcription, DNA-dependent ESC/E(Z) complex DNA binding, transcription corepressor activity, zinc ion binding Human AEN HPA UniProtKB {GO:0042771=PMID:18264133, GO:0004527=PMID:18264133, GO:0010212=PMID:16171785, GO:0005730=GO_REF:0000052, GO:0005654=PMID:16171785, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002} Q8WTP8 Apoptosis-enhancing nuclease protein 20120912 {GO:0042771=IDA, GO:0004527=IDA, GO:0010212=IDA, GO:0005730=IDA, GO:0005654=IDA, GO:0005634=IDA, GO:0003676=IEA} intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, response to ionizing radiation nucleolus, nucleoplasm, nucleus exonuclease activity, nucleic acid binding Human AES BHF-UCL UniProtKB {GO:0005515=PMID:22952044, GO:0032091=PMID:15489227, GO:0060761=PMID:15489227, GO:0003714=PMID:10660609, GO:0007275=PMID:8365415, GO:0000122=PMID:10660609, GO:0006351=GO_REF:0000037, GO:0001501=GO_REF:0000019, GO:0031668=GO_REF:0000019, GO:0009887=PMID:9809752, GO:0016055=GO_REF:0000037, GO:0045892=PMID:19460168, GO:0090090=PMID:19460168, GO:0070555=PMID:15489227, GO:0040008=GO_REF:0000019} Q08117 Amino-terminal enhancer of split protein 20090629 {GO:0005515=IPI, GO:0032091=IDA, GO:0060761=IMP, GO:0003714=IPI, GO:0007275=TAS, GO:0000122=IMP, GO:0006351=IEA, GO:0001501=IEA, GO:0031668=IEA, GO:0009887=TAS, GO:0016055=IEA, GO:0045892=IDA, GO:0090090=IDA, GO:0070555=IDA, GO:0040008=IEA} Wnt receptor signaling pathway, cellular response to extracellular stimulus, multicellular organismal development, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of protein binding, negative regulation of response to cytokine stimulus, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, organ morphogenesis, regulation of growth, response to interleukin-1, skeletal system development, transcription, DNA-dependent protein binding, transcription corepressor activity Human AFAP1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0003779=GO_REF:0000037, GO:0015629=GO_REF:0000052, GO:0005925=GO_REF:0000052} Q8N556 Actin filament-associated protein 1 protein 20101115 {GO:0005737=IDA, GO:0005543=IEA, GO:0003779=IEA, GO:0015629=IDA, GO:0005925=IDA} actin cytoskeleton, cytoplasm, focal adhesion actin binding, phospholipid binding Human AFAP1L1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0005543=GO_REF:0000002, GO:0071437=GO_REF:0000039, GO:0002102=GO_REF:0000039} Q8TED9 Actin filament-associated protein 1-like 1 protein 20130413 {GO:0005737=IEA, GO:0030054=IEA, GO:0005543=IEA, GO:0071437=IEA, GO:0002102=IEA} cell junction, cytoplasm, invadopodium, podosome phospholipid binding Human UniProtKB-SubCell:SL-0148 AFAP1L2 HPA UniProtKB {GO:0017124=PMID:17412687, GO:0005886=GO_REF:0000052, GO:0016235=GO_REF:0000052, GO:0045742=PMID:17412687, GO:0061098=PMID:17412687, GO:0005634=GO_REF:0000052, GO:0032757=PMID:17412687, GO:0007346=PMID:17412687, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0006954=PMID:17412687, GO:0030296=PMID:17412687, GO:0032675=PMID:17412687, GO:0045893=PMID:17412687, GO:0042169=PMID:17412687} Q8N4X5 Actin filament-associated protein 1-like 2 protein 20110516 {GO:0017124=IPI, GO:0005886=IDA, GO:0016235=IDA, GO:0045742=IDA, GO:0061098=IDA, GO:0005634=IDA, GO:0032757=IDA, GO:0007346=IDA, GO:0005737=IDA, GO:0005543=IEA, GO:0006954=IDA, GO:0030296=IDA, GO:0032675=IDA, GO:0045893=IDA, GO:0042169=IPI} inflammatory response, positive regulation of epidermal growth factor receptor signaling pathway, positive regulation of interleukin-8 production, positive regulation of protein tyrosine kinase activity, positive regulation of transcription, DNA-dependent, regulation of interleukin-6 production, regulation of mitotic cell cycle aggresome, cytoplasm, nucleus, plasma membrane SH2 domain binding, SH3 domain binding, phospholipid binding, protein tyrosine kinase activator activity Human AFF1 GOC UniProtKB {GO:0005515=PMID:22190034, GO:0006355=PMID:7689231, GO:0003700=PMID:7689231, GO:0005634=GO_REF:0000039, GO:0045893=GO_REF:0000019} P51825 AF4/FMR2 family member 1 protein 20130413 {GO:0005515=IPI, GO:0006355=TAS, GO:0003700=TAS, GO:0005634=IEA, GO:0045893=IEA} positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent nucleus protein binding, sequence-specific DNA binding transcription factor activity Human AFF2 PINC UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0016607=PMID:19136466, GO:0007420=PMID:8673086, GO:0002151=GO_REF:0000024, GO:0007611=GO_REF:0000019, GO:0043484=PMID:19136466} P51816 AF4/FMR2 family member 2 protein 20031120 {GO:0008380=IEA, GO:0006397=IEA, GO:0016607=IDA, GO:0007420=TAS, GO:0002151=ISS, GO:0007611=IEA, GO:0043484=IMP} RNA splicing, brain development, learning or memory, mRNA processing, regulation of RNA splicing nuclear speck G-quadruplex RNA binding Human AFF3 HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0003690=PMID:8555498, GO:0005730=GO_REF:0000052, GO:0035116=PMID:18616733, GO:0034612=PMID:20444755, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037} P51826 AF4/FMR2 family member 3 protein 20111111 {GO:0006355=IEA, GO:0003690=IDA, GO:0005730=IDA, GO:0035116=IMP, GO:0034612=IMP, GO:0005634=IDA, GO:0006351=IEA} embryonic hindlimb morphogenesis, regulation of transcription, DNA-dependent, response to tumor necrosis factor, transcription, DNA-dependent nucleolus, nucleus double-stranded DNA binding Human AFF4 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005515=PMID:22190034, GO:0003700=PMID:10588740, GO:0006366=PMID:10588740, GO:0005730=GO_REF:0000052, GO:0007286=GO_REF:0000019, GO:0005634=GO_REF:0000052} Q9UHB7 AF4/FMR2 family member 4 protein 20101115 {GO:0005739=IDA, GO:0005515=IPI, GO:0003700=TAS, GO:0006366=TAS, GO:0005730=IDA, GO:0007286=IEA, GO:0005634=IDA} spermatid development, transcription from RNA polymerase II promoter mitochondrion, nucleolus, nucleus protein binding, sequence-specific DNA binding transcription factor activity Human AFG3L2 HPA UniProtKB {GO:0005515=PMID:14623864, GO:0008219=GO_REF:0000037, GO:0017111=GO_REF:0000002, GO:0034982=GO_REF:0000019, GO:0042552=GO_REF:0000019, GO:0005743=GO_REF:0000019, GO:0021675=GO_REF:0000019, GO:0007409=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0005739=GO_REF:0000052, GO:0030163=GO_REF:0000002, GO:0008053=GO_REF:0000019, GO:0007528=GO_REF:0000019, GO:0040014=GO_REF:0000019, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0051082=PMID:10395799, GO:0016021=GO_REF:0000037, GO:0004222=GO_REF:0000002, GO:0042407=GO_REF:0000019, GO:0060013=GO_REF:0000019} Q9Y4W6 AFG3-like protein 2 protein 20101115 {GO:0005515=IPI, GO:0008219=IEA, GO:0017111=IEA, GO:0034982=IEA, GO:0042552=IEA, GO:0005743=IEA, GO:0021675=IEA, GO:0007409=IEA, GO:0005524=IEA, GO:0005739=IDA, GO:0030163=IEA, GO:0008053=IEA, GO:0007528=IEA, GO:0040014=IEA, GO:0006508=IEA, GO:0008270=IEA, GO:0051082=TAS, GO:0016021=IEA, GO:0004222=IEA, GO:0042407=IEA, GO:0060013=IEA} axonogenesis, cell death, cristae formation, mitochondrial fusion, mitochondrial protein processing, myelination, nerve development, neuromuscular junction development, protein catabolic process, proteolysis, regulation of multicellular organism growth, righting reflex integral to membrane, mitochondrial inner membrane, mitochondrion ATP binding, metalloendopeptidase activity, nucleoside-triphosphatase activity, protein binding, unfolded protein binding, zinc ion binding Human AFMID Reactome UniProtKB {GO:0034641=Reactome:REACT_13, GO:0006569=Reactome:REACT_916, GO:0019441=GO_REF:0000041, GO:0016787=GO_REF:0000002, GO:0004061=GO_REF:0000003, GO:0005634=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0005829=GO_REF:0000039} Q63HM1 Kynurenine formamidase protein 20130301 {GO:0034641=TAS, GO:0006569=TAS, GO:0019441=IEA, GO:0016787=IEA, GO:0004061=IEA, GO:0005634=IEA, GO:0044281=TAS, GO:0005829=IEA} cellular nitrogen compound metabolic process, small molecule metabolic process, tryptophan catabolic process, tryptophan catabolic process to kynurenine cytosol, nucleus arylformamidase activity, hydrolase activity Human AFP ENSEMBL UniProtKB {GO:0005737=GO_REF:0000019, GO:0042448=GO_REF:0000019, GO:0006810=GO_REF:0000002, GO:0001542=GO_REF:0000019, GO:0060395=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0046872=GO_REF:0000037} P02771 Alpha-fetoprotein protein 20130413 {GO:0005737=IEA, GO:0042448=IEA, GO:0006810=IEA, GO:0001542=IEA, GO:0060395=IEA, GO:0005615=IEA, GO:0046872=IEA} SMAD protein signal transduction, ovulation from ovarian follicle, progesterone metabolic process, transport cytoplasm, extracellular space metal ion binding Human Ensembl:ENSMUSP00000041006 AFTPH HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0030121=PMID:15758025, GO:0030276=PMID:15758025, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0015031=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0005829=PMID:15758025} Q6ULP2 Aftiphilin protein 20101115 {GO:0005737=IDA, GO:0005794=IDA, GO:0030121=IDA, GO:0030276=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0015031=IEA, GO:0043231=IDA, GO:0005829=IDA} protein transport AP-1 adaptor complex, Golgi apparatus, cytoplasm, cytosol, intracellular membrane-bounded organelle, nucleolus, nucleus clathrin binding Human AGA UniProtKB UniProtKB {GO:0051604=GO_REF:0000019, GO:0016787=GO_REF:0000002, GO:0005783=PMID:8776587, GO:0006517=PMID:1281977, GO:0006508=GO_REF:0000037, GO:0003948=PMID:1281977, GO:0008233=GO_REF:0000037, GO:0043621=GO_REF:0000019, GO:0005764=PMID:8776587} P20933 N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase protein 20100514 {GO:0051604=IEA, GO:0016787=IEA, GO:0005783=IDA, GO:0006517=IDA, GO:0006508=IEA, GO:0003948=IDA, GO:0008233=IEA, GO:0043621=IEA, GO:0005764=IDA} protein deglycosylation, protein maturation, proteolysis endoplasmic reticulum, lysosome N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity, hydrolase activity, peptidase activity, protein self-association Human AGAP1 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0008060=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0032312=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0015031=GO_REF:0000037, GO:0005525=GO_REF:0000037} Q9UPQ3 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 protein 20130413 {GO:0005622=IEA, GO:0008060=IEA, GO:0005737=IEA, GO:0005543=IEA, GO:0032312=IEA, GO:0007264=IEA, GO:0008270=IEA, GO:0015031=IEA, GO:0005525=IEA} protein transport, regulation of ARF GTPase activity, small GTPase mediated signal transduction cytoplasm, intracellular ARF GTPase activator activity, GTP binding, phospholipid binding, zinc ion binding Human UniProtKB-SubCell:SL-0086 AGAP2 HPA UniProtKB {GO:0043066=GO_REF:0000019, GO:0019901=GO_REF:0000019, GO:0042177=PMID:18374643, GO:0007264=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0030295=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0005525=GO_REF:0000037, GO:0046427=GO_REF:0000019, GO:0005622=GO_REF:0000002, GO:0005739=GO_REF:0000052, GO:0008060=GO_REF:0000002, GO:0043524=PMID:18374643, GO:0005543=GO_REF:0000002, GO:0007411=Reactome:REACT_18266, GO:0032312=GO_REF:0000002, GO:0045944=GO_REF:0000019, GO:2001240=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0033601=GO_REF:0000019, GO:0060749=GO_REF:0000019} Q99490 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 protein 20101115 {GO:0043066=IEA, GO:0019901=IEA, GO:0042177=IDA, GO:0007264=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0030295=IEA, GO:0015031=IEA, GO:0005525=IEA, GO:0046427=IEA, GO:0005622=IEA, GO:0005739=IDA, GO:0008060=IEA, GO:0043524=IGI, GO:0005543=IEA, GO:0007411=TAS, GO:0032312=IEA, GO:0045944=IEA, GO:2001240=IEA, GO:0008270=IEA, GO:0033601=IEA, GO:0060749=IEA} axon guidance, mammary gland alveolus development, negative regulation of apoptotic process, negative regulation of extrinsic apoptotic signaling pathway in absence of ligand, negative regulation of neuron apoptotic process, negative regulation of protein catabolic process, positive regulation of JAK-STAT cascade, positive regulation of mammary gland epithelial cell proliferation, positive regulation of transcription from RNA polymerase II promoter, protein transport, regulation of ARF GTPase activity, small GTPase mediated signal transduction intracellular, mitochondrion, nucleolus, nucleus ARF GTPase activator activity, GTP binding, phospholipid binding, protein kinase activator activity, protein kinase binding, zinc ion binding Human AGAP3 UniProtKB UniProtKB {GO:0007264=GO_REF:0000002, GO:0003924=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0005525=GO_REF:0000037, GO:0071944=GO_REF:0000019, GO:0005622=GO_REF:0000002, GO:0008060=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0032312=GO_REF:0000002, GO:0034614=GO_REF:0000019, GO:0043161=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0000060=GO_REF:0000019, GO:0031593=GO_REF:0000019} Q96P47 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 protein 20130413 {GO:0007264=IEA, GO:0003924=IEA, GO:0005634=IEA, GO:0005525=IEA, GO:0071944=IEA, GO:0005622=IEA, GO:0008060=IEA, GO:0007165=IEA, GO:0005737=IEA, GO:0005543=IEA, GO:0016020=IEA, GO:0032312=IEA, GO:0034614=IEA, GO:0043161=IEA, GO:0008270=IEA, GO:0000060=IEA, GO:0031593=IEA} cellular response to reactive oxygen species, proteasomal ubiquitin-dependent protein catabolic process, protein import into nucleus, translocation, regulation of ARF GTPase activity, signal transduction, small GTPase mediated signal transduction cell periphery, cytoplasm, intracellular, membrane, nucleus ARF GTPase activator activity, GTP binding, GTPase activity, phospholipid binding, polyubiquitin binding, zinc ion binding Human UniProtKB-SubCell:SL-0086 AGAP4 InterPro UniProtKB {GO:0008060=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0032312=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q96P64 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4 protein 20130413 {GO:0008060=IEA, GO:0005543=IEA, GO:0032312=IEA, GO:0008270=IEA} regulation of ARF GTPase activity ARF GTPase activator activity, phospholipid binding, zinc ion binding Human InterPro:IPR001164 AGBL2 UniProtKB UniProtKB {GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0004181=GO_REF:0000002, GO:0005829=GO_REF:0000024} Q5U5Z8 Cytosolic carboxypeptidase 2 protein 20101123 {GO:0006508=IEA, GO:0008270=IEA, GO:0004181=IEA, GO:0005829=ISS} proteolysis cytosol metallocarboxypeptidase activity, zinc ion binding Human UniProtKB:Q8CDK2 AGBL5 LIFEdb UniProtKB {GO:0005737=GO_REF:0000054, GO:0015631=GO_REF:0000024, GO:0035611=GO_REF:0000024, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000024, GO:0035608=GO_REF:0000024, GO:0005829=GO_REF:0000024, GO:0004181=GO_REF:0000024} Q8NDL9 Cytosolic carboxypeptidase-like protein 5 protein 20100607 {GO:0005737=IDA, GO:0015631=ISS, GO:0035611=ISS, GO:0006508=IEA, GO:0008270=IEA, GO:0005634=ISS, GO:0035608=ISS, GO:0005829=ISS, GO:0004181=ISS} protein branching point deglutamylation, protein deglutamylation, proteolysis cytoplasm, cytosol, nucleus metallocarboxypeptidase activity, tubulin binding, zinc ion binding Human AGER UniProtKB UniProtKB {GO:0005515=PMID:21706016, GO:0005886=Reactome:REACT_25382, GO:0009611=PMID:10399917, GO:0005576=GO_REF:0000039, GO:0031175=PMID:10391939, GO:0050930=GO_REF:0000019, GO:0044548=PMID:15033494, GO:0006954=GO_REF:0000037, GO:0051092=PMID:10391939, GO:0016020=GO_REF:0000038, GO:0005887=PMID:1378843, GO:0045087=Reactome:REACT_6802, GO:0004872=PMID:8751438, GO:0007166=PMID:10835680, GO:0004888=PMID:1378843} Q5SSZ2 Advanced glycosylation end product-specific receptor protein 20130413 {GO:0005515=IPI, GO:0005886=TAS, GO:0009611=TAS, GO:0005576=IEA, GO:0031175=IGI, GO:0050930=IEA, GO:0044548=IPI, GO:0006954=IEA, GO:0051092=IDA, GO:0016020=IEA, GO:0005887=TAS, GO:0045087=TAS, GO:0004872=TAS, GO:0007166=TAS, GO:0004888=TAS} cell surface receptor signaling pathway, induction of positive chemotaxis, inflammatory response, innate immune response, neuron projection development, positive regulation of NF-kappaB transcription factor activity, response to wounding extracellular region, integral to plasma membrane, membrane, plasma membrane S100 protein binding, protein binding, receptor activity, transmembrane signaling receptor activity Human UniProtKB-KW:KW-0472 AGFG1 HPA UniProtKB {GO:0005515=PMID:18775314, GO:0005794=GO_REF:0000052, GO:0003723=PMID:7634337, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0008060=GO_REF:0000002, GO:0006406=PMID:7634337, GO:0032312=GO_REF:0000002, GO:0005643=PMID:7637788, GO:0016023=GO_REF:0000039, GO:0008270=GO_REF:0000002} P52594 Arf-GAP domain and FG repeat-containing protein 1 protein 20081203 {GO:0005515=IPI, GO:0005794=IDA, GO:0003723=TAS, GO:0007275=IEA, GO:0007283=IEA, GO:0003677=IEA, GO:0030154=IEA, GO:0043231=IDA, GO:0008060=IEA, GO:0006406=TAS, GO:0032312=IEA, GO:0005643=TAS, GO:0016023=IEA, GO:0008270=IEA} cell differentiation, mRNA export from nucleus, multicellular organismal development, regulation of ARF GTPase activity, spermatogenesis Golgi apparatus, cytoplasmic membrane-bounded vesicle, intracellular membrane-bounded organelle, nuclear pore ARF GTPase activator activity, DNA binding, RNA binding, protein binding, zinc ion binding Human AGFG2 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0008060=GO_REF:0000002, GO:0032312=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0005575=GO_REF:0000015} O95081 Arf-GAP domain and FG repeat-containing protein 2 protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0008060=IEA, GO:0032312=IEA, GO:0008270=IEA, GO:0005575=ND} biological_process, regulation of ARF GTPase activity cellular_component ARF GTPase activator activity, molecular_function, zinc ion binding Human AGGF1 UniProtKB UniProtKB {GO:0005515=PMID:14961121, GO:0006396=PMID:15486042, GO:0005737=PMID:14961121, GO:0048471=PMID:14961121, GO:0043499=PMID:14961121, GO:0001938=PMID:14961121, GO:0005576=PMID:14961121, GO:0001525=GO_REF:0000037, GO:0007155=PMID:14961121, GO:0003676=GO_REF:0000002, GO:0001570=PMID:15905966, GO:0045766=PMID:14961121} Q8N302 Angiogenic factor with G patch and FHA domains 1 protein 20051122 {GO:0005515=IPI, GO:0006396=TAS, GO:0005737=IDA, GO:0048471=IDA, GO:0043499=IDA, GO:0001938=IDA, GO:0005576=IDA, GO:0001525=IEA, GO:0007155=IDA, GO:0003676=IEA, GO:0001570=TAS, GO:0045766=IDA} RNA processing, angiogenesis, cell adhesion, positive regulation of angiogenesis, positive regulation of endothelial cell proliferation, vasculogenesis cytoplasm, extracellular region, perinuclear region of cytoplasm eukaryotic cell surface binding, nucleic acid binding, protein binding Human AGK UniPathway UniProtKB {GO:0031966=GO_REF:0000039, GO:0004143=GO_REF:0000003, GO:0047620=GO_REF:0000003, GO:0046486=GO_REF:0000041, GO:0046513=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0001729=GO_REF:0000019, GO:0007205=GO_REF:0000002} Q53H12 Acylglycerol kinase, mitochondrial protein 20130413 {GO:0031966=IEA, GO:0004143=IEA, GO:0047620=IEA, GO:0046486=IEA, GO:0046513=IEA, GO:0005524=IEA, GO:0001729=IEA, GO:0007205=IEA} ceramide biosynthetic process, glycerolipid metabolic process, protein kinase C-activating G-protein coupled receptor signaling pathway mitochondrial membrane ATP binding, acylglycerol kinase activity, ceramide kinase activity, diacylglycerol kinase activity Human UniPathway:UPA00230 AGL HPA UniProtKB {GO:0005515=PMID:17908927, GO:0043033=PMID:1374391, GO:0005975=Reactome:REACT_474, GO:0007584=GO_REF:0000019, GO:0016234=GO_REF:0000019, GO:0005978=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0051384=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_1507, GO:0005737=GO_REF:0000052, GO:0016529=GO_REF:0000019, GO:0004134=GO_REF:0000033, GO:0006006=Reactome:REACT_723, GO:0004135=GO_REF:0000033, GO:0030247=GO_REF:0000019, GO:0005980=Reactome:REACT_1008, GO:0031593=GO_REF:0000019, GO:0004133=PMID:1374391} P35573 Glycogen debranching enzyme protein 20100326 {GO:0005515=IPI, GO:0043033=TAS, GO:0005975=TAS, GO:0007584=IEA, GO:0016234=IEA, GO:0005978=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0051384=IEA, GO:0044281=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0016529=IEA, GO:0004134=IBA, GO:0006006=TAS, GO:0004135=IBA, GO:0030247=IEA, GO:0005980=TAS, GO:0031593=IEA, GO:0004133=TAS} carbohydrate metabolic process, glucose metabolic process, glycogen biosynthetic process, glycogen catabolic process, response to glucocorticoid stimulus, response to nutrient, small molecule metabolic process cytoplasm, cytosol, inclusion body, isoamylase complex, nucleolus, nucleus, sarcoplasmic reticulum 4-alpha-glucanotransferase activity, amylo-alpha-1,6-glucosidase activity, glycogen debranching enzyme activity, polysaccharide binding, polyubiquitin binding, protein binding Human AGMAT Reactome UniProtKB {GO:0005739=Reactome:REACT_14815, GO:0008295=GO_REF:0000037, GO:0034641=Reactome:REACT_13, GO:0008783=GO_REF:0000003, GO:0006595=Reactome:REACT_14820, GO:0033388=GO_REF:0000041, GO:0044281=Reactome:REACT_111217, GO:0097055=Reactome:REACT_14800, GO:0046872=GO_REF:0000037} Q9BSE5 Agmatinase, mitochondrial protein 20130301 {GO:0005739=TAS, GO:0008295=IEA, GO:0034641=TAS, GO:0008783=IEA, GO:0006595=TAS, GO:0033388=IEA, GO:0044281=TAS, GO:0097055=TAS, GO:0046872=IEA} agmatine biosynthetic process, cellular nitrogen compound metabolic process, polyamine metabolic process, putrescine biosynthetic process from arginine, small molecule metabolic process, spermidine biosynthetic process mitochondrion agmatinase activity, metal ion binding Human AGPAT1 ENSEMBL UniProtKB {GO:0005783=PMID:9461603, GO:0001819=PMID:9212163, GO:0044281=Reactome:REACT_111217, GO:0003841=GO_REF:0000019, GO:0006112=Reactome:REACT_1505, GO:0031325=Reactome:REACT_2122, GO:0001961=PMID:9212163, GO:0016024=GO_REF:0000041, GO:0005789=Reactome:REACT_2042, GO:0019432=Reactome:REACT_1190, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0006654=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0046474=Reactome:REACT_121401} Q9HBM8 cDNA, FLJ78849, highly similar to 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (EC 2.3.1.51) protein 20130413 {GO:0005783=TAS, GO:0001819=IMP, GO:0044281=TAS, GO:0003841=IEA, GO:0006112=TAS, GO:0031325=TAS, GO:0001961=IC, GO:0016024=IEA, GO:0005789=TAS, GO:0019432=TAS, GO:0016021=IEA, GO:0006644=TAS, GO:0006654=IEA, GO:0044255=TAS, GO:0046474=TAS} CDP-diacylglycerol biosynthetic process, cellular lipid metabolic process, energy reserve metabolic process, glycerophospholipid biosynthetic process, phosphatidic acid biosynthetic process, phospholipid metabolic process, positive regulation of cellular metabolic process, positive regulation of cytokine production, positive regulation of cytokine-mediated signaling pathway, small molecule metabolic process, triglyceride biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane 1-acylglycerol-3-phosphate O-acyltransferase activity Human Ensembl:ENSMUSP00000048573 AGPAT2 BHF-UCL UniProtKB {GO:0005783=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0001819=PMID:9212163, GO:0003841=PMID:9212163, GO:0001961=PMID:9212163, GO:0016024=GO_REF:0000041, GO:0005789=Reactome:REACT_2042, GO:0019432=Reactome:REACT_1190, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0006654=PMID:9212163, GO:0044255=Reactome:REACT_22279, GO:0046474=Reactome:REACT_121401} O15120 1-acyl-sn-glycerol-3-phosphate acyltransferase beta protein 20090403 {GO:0005783=ISS, GO:0044281=TAS, GO:0001819=IMP, GO:0003841=IGI, GO:0001961=IC, GO:0016024=IEA, GO:0005789=TAS, GO:0019432=TAS, GO:0016021=IEA, GO:0006644=TAS, GO:0006654=IGI, GO:0044255=TAS, GO:0046474=TAS} CDP-diacylglycerol biosynthetic process, cellular lipid metabolic process, glycerophospholipid biosynthetic process, phosphatidic acid biosynthetic process, phospholipid metabolic process, positive regulation of cytokine production, positive regulation of cytokine-mediated signaling pathway, small molecule metabolic process, triglyceride biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane 1-acylglycerol-3-phosphate O-acyltransferase activity Human AGPAT3 Reactome UniProtKB {GO:0016746=GO_REF:0000002, GO:0005886=PMID:16780588, GO:0005783=PMID:16780588, GO:0044281=Reactome:REACT_111217, GO:0005635=GO_REF:0000039, GO:0008654=PMID:15367102, GO:0003841=PMID:15367102, GO:0016024=GO_REF:0000041, GO:0005789=Reactome:REACT_2042, GO:0019432=Reactome:REACT_1190, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0006654=Reactome:REACT_120906, GO:0044255=Reactome:REACT_22279, GO:0046474=Reactome:REACT_121401} Q9NRZ7 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma protein 20130301 {GO:0016746=IEA, GO:0005886=IDA, GO:0005783=IDA, GO:0044281=TAS, GO:0005635=IEA, GO:0008654=NAS, GO:0003841=NAS, GO:0016024=IEA, GO:0005789=TAS, GO:0019432=TAS, GO:0016021=IEA, GO:0006644=TAS, GO:0006654=TAS, GO:0044255=TAS, GO:0046474=TAS} CDP-diacylglycerol biosynthetic process, cellular lipid metabolic process, glycerophospholipid biosynthetic process, phosphatidic acid biosynthetic process, phospholipid biosynthetic process, phospholipid metabolic process, small molecule metabolic process, triglyceride biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, nuclear envelope, plasma membrane 1-acylglycerol-3-phosphate O-acyltransferase activity, transferase activity, transferring acyl groups Human AGPAT4 Reactome UniProtKB {GO:0016746=GO_REF:0000038, GO:0019432=Reactome:REACT_1190, GO:0005789=Reactome:REACT_2042, GO:0016024=GO_REF:0000041, GO:0044281=Reactome:REACT_111217, GO:0008654=PMID:15367102, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0006654=Reactome:REACT_120906, GO:0003841=PMID:15367102, GO:0044255=Reactome:REACT_22279, GO:0046474=Reactome:REACT_121401} Q9NRZ5 1-acyl-sn-glycerol-3-phosphate acyltransferase delta protein 20130301 {GO:0016746=IEA, GO:0019432=TAS, GO:0005789=TAS, GO:0016024=IEA, GO:0044281=TAS, GO:0008654=NAS, GO:0016021=IEA, GO:0006644=TAS, GO:0006654=TAS, GO:0003841=NAS, GO:0044255=TAS, GO:0046474=TAS} CDP-diacylglycerol biosynthetic process, cellular lipid metabolic process, glycerophospholipid biosynthetic process, phosphatidic acid biosynthetic process, phospholipid biosynthetic process, phospholipid metabolic process, small molecule metabolic process, triglyceride biosynthetic process endoplasmic reticulum membrane, integral to membrane 1-acylglycerol-3-phosphate O-acyltransferase activity, transferase activity, transferring acyl groups Human AGPAT5 Reactome UniProtKB {GO:0005741=Reactome:REACT_121245, GO:0005635=GO_REF:0000039, GO:0008654=PMID:15367102, GO:0044281=Reactome:REACT_111217, GO:0003841=PMID:15367102, GO:0005739=GO_REF:0000054, GO:0016024=GO_REF:0000041, GO:0005789=Reactome:REACT_2042, GO:0019432=Reactome:REACT_1190, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0006654=Reactome:REACT_120906, GO:0044255=Reactome:REACT_22279, GO:0046474=Reactome:REACT_121401} Q9NUQ2 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon protein 20130301 {GO:0005741=TAS, GO:0005635=IEA, GO:0008654=NAS, GO:0044281=TAS, GO:0003841=NAS, GO:0005739=IDA, GO:0016024=IEA, GO:0005789=TAS, GO:0019432=TAS, GO:0016021=IEA, GO:0006644=TAS, GO:0006654=TAS, GO:0044255=TAS, GO:0046474=TAS} CDP-diacylglycerol biosynthetic process, cellular lipid metabolic process, glycerophospholipid biosynthetic process, phosphatidic acid biosynthetic process, phospholipid biosynthetic process, phospholipid metabolic process, small molecule metabolic process, triglyceride biosynthetic process endoplasmic reticulum membrane, integral to membrane, mitochondrial outer membrane, mitochondrion, nuclear envelope 1-acylglycerol-3-phosphate O-acyltransferase activity Human AGPAT6 Reactome UniProtKB {GO:0006637=PMID:18238778, GO:0008610=GO_REF:0000024, GO:0005783=PMID:18238778, GO:0004366=PMID:18238778, GO:0044281=Reactome:REACT_111217, GO:0003841=PMID:18238778, GO:0007595=GO_REF:0000024, GO:0016020=PMID:18238778, GO:0040014=GO_REF:0000019, GO:0005789=Reactome:REACT_22419, GO:0006631=GO_REF:0000019, GO:0019432=Reactome:REACT_1190, GO:0016024=GO_REF:0000041, GO:0002071=GO_REF:0000019, GO:0016021=PMID:18238778, GO:0006644=Reactome:REACT_120870, GO:0006654=Reactome:REACT_120906, GO:0044255=Reactome:REACT_22279, GO:0046474=Reactome:REACT_121401, GO:0006656=PMID:18238778, GO:0046339=GO_REF:0000019} Q86UL3 Glycerol-3-phosphate acyltransferase 4 protein 20130301 {GO:0006637=IDA, GO:0008610=ISS, GO:0005783=IDA, GO:0004366=IDA, GO:0044281=TAS, GO:0003841=IDA, GO:0007595=ISS, GO:0016020=IDA, GO:0040014=IEA, GO:0005789=TAS, GO:0006631=IEA, GO:0019432=TAS, GO:0016024=IEA, GO:0002071=IEA, GO:0016021=NAS, GO:0006644=TAS, GO:0006654=TAS, GO:0044255=TAS, GO:0046474=TAS, GO:0006656=IDA, GO:0046339=IEA} CDP-diacylglycerol biosynthetic process, acyl-CoA metabolic process, cellular lipid metabolic process, diacylglycerol metabolic process, fatty acid metabolic process, glandular epithelial cell maturation, glycerophospholipid biosynthetic process, lactation, lipid biosynthetic process, phosphatidic acid biosynthetic process, phosphatidylcholine biosynthetic process, phospholipid metabolic process, regulation of multicellular organism growth, small molecule metabolic process, triglyceride biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, membrane 1-acylglycerol-3-phosphate O-acyltransferase activity, glycerol-3-phosphate O-acyltransferase activity Human AGPAT9 Reactome UniProtKB {GO:0032006=PMID:17002884, GO:0005783=PMID:17170135, GO:0016024=GO_REF:0000041, GO:0019432=Reactome:REACT_1190, GO:0005789=Reactome:REACT_2042, GO:0004366=PMID:17170135, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0006654=Reactome:REACT_120906, GO:0044255=Reactome:REACT_22279, GO:0046474=Reactome:REACT_121401} Q53EU6 Glycerol-3-phosphate acyltransferase 3 protein 20130301 {GO:0032006=IDA, GO:0005783=IDA, GO:0016024=IEA, GO:0019432=TAS, GO:0005789=TAS, GO:0004366=IDA, GO:0044281=TAS, GO:0016021=IEA, GO:0006644=TAS, GO:0006654=TAS, GO:0044255=TAS, GO:0046474=TAS} CDP-diacylglycerol biosynthetic process, cellular lipid metabolic process, glycerophospholipid biosynthetic process, phosphatidic acid biosynthetic process, phospholipid metabolic process, regulation of TOR signaling cascade, small molecule metabolic process, triglyceride biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane glycerol-3-phosphate O-acyltransferase activity Human AGPHD1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0047992=GO_REF:0000003} A2RU49 Hydroxylysine kinase protein 20130413 {GO:0005737=IEA, GO:0047992=IEA} cytoplasm hydroxylysine kinase activity Human UniProtKB-SubCell:SL-0086 AGPS HPA UniProtKB {GO:0008610=PMID:9553082, GO:0008762=GO_REF:0000002, GO:0005782=Reactome:REACT_16930, GO:0008611=Reactome:REACT_1407, GO:0050660=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0043231=GO_REF:0000052, GO:0005739=GO_REF:0000019, GO:0071949=GO_REF:0000024, GO:0008609=PMID:9553082, GO:0005778=PMID:21525035, GO:0044255=Reactome:REACT_16957, GO:0005777=PMID:9553082} O00116 Alkyldihydroxyacetonephosphate synthase, peroxisomal protein 20111111 {GO:0008610=IDA, GO:0008762=IEA, GO:0005782=TAS, GO:0008611=TAS, GO:0050660=IEA, GO:0044281=TAS, GO:0043231=IDA, GO:0005739=IEA, GO:0071949=ISS, GO:0008609=IDA, GO:0005778=IDA, GO:0044255=TAS, GO:0005777=IDA} cellular lipid metabolic process, ether lipid biosynthetic process, lipid biosynthetic process, small molecule metabolic process intracellular membrane-bounded organelle, mitochondrion, peroxisomal matrix, peroxisomal membrane, peroxisome FAD binding, UDP-N-acetylmuramate dehydrogenase activity, alkylglycerone-phosphate synthase activity, flavin adenine dinucleotide binding Human AGR2 UniProtKB UniProtKB {GO:0005515=PMID:12592373, GO:0070254=GO_REF:0000024, GO:0005739=GO_REF:0000019, GO:0002162=PMID:12592373, GO:0005783=GO_REF:0000024, GO:0005576=GO_REF:0000039} O95994 Anterior gradient protein 2 homolog protein 20120708 {GO:0005515=IPI, GO:0070254=ISS, GO:0005739=IEA, GO:0002162=IDA, GO:0005783=ISS, GO:0005576=IEA} mucus secretion endoplasmic reticulum, extracellular region, mitochondrion dystroglycan binding, protein binding Human UniProtKB:Q14118 AGR3 UniProtKB UniProtKB {GO:0005515=PMID:12592373, GO:0002162=PMID:12592373, GO:0005576=GO_REF:0000039} Q8TD06 Anterior gradient protein 3 homolog protein 20120708 {GO:0005515=IPI, GO:0002162=IDA, GO:0005576=IEA} extracellular region dystroglycan binding, protein binding Human UniProtKB:Q14118 AGRN IntAct UniProtKB {GO:0005515=PMID:21078624, GO:0002162=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0007603=Reactome:REACT_160125, GO:0005886=Reactome:REACT_160272, GO:0045202=GO_REF:0000024, GO:0051491=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0035374=GO_REF:0000024, GO:0007411=Reactome:REACT_18266, GO:0045944=GO_REF:0000024, GO:0033691=GO_REF:0000024, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408, GO:0043202=Reactome:REACT_121392, GO:0005975=Reactome:REACT_474, GO:0005796=Reactome:REACT_121320, GO:0045887=GO_REF:0000024, GO:0005509=GO_REF:0000024, GO:0005605=PMID:9405491, GO:0006027=Reactome:REACT_120752, GO:0043395=GO_REF:0000024, GO:0007213=PMID:9405491, GO:0001523=Reactome:REACT_24968, GO:0006024=Reactome:REACT_121248, GO:0031012=PMID:17628813, GO:0007165=PMID:9652404, GO:0045162=PMID:9405491, GO:0050808=PMID:9652404, GO:0032321=GO_REF:0000024, GO:0043236=PMID:9652404, GO:0005200=PMID:9652404, GO:0043113=PMID:15340048, GO:0016021=GO_REF:0000037} O00468 Agrin protein 20130415 {GO:0005515=IPI, GO:0002162=ISS, GO:0030054=IEA, GO:0007603=TAS, GO:0005886=TAS, GO:0045202=ISS, GO:0051491=ISS, GO:0044281=TAS, GO:0035374=ISS, GO:0007411=TAS, GO:0045944=ISS, GO:0033691=ISS, GO:0030204=TAS, GO:0030203=TAS, GO:0043202=TAS, GO:0005975=TAS, GO:0005796=TAS, GO:0045887=ISS, GO:0005509=ISS, GO:0005605=IDA, GO:0006027=TAS, GO:0043395=ISS, GO:0007213=TAS, GO:0001523=TAS, GO:0006024=TAS, GO:0031012=IDA, GO:0007165=TAS, GO:0045162=TAS, GO:0050808=TAS, GO:0032321=ISS, GO:0043236=TAS, GO:0005200=TAS, GO:0043113=IDA, GO:0016021=IEA} G-protein coupled acetylcholine receptor signaling pathway, axon guidance, carbohydrate metabolic process, chondroitin sulfate metabolic process, clustering of voltage-gated sodium channels, glycosaminoglycan biosynthetic process, glycosaminoglycan catabolic process, glycosaminoglycan metabolic process, phototransduction, visible light, positive regulation of Rho GTPase activity, positive regulation of filopodium assembly, positive regulation of synaptic growth at neuromuscular junction, positive regulation of transcription from RNA polymerase II promoter, receptor clustering, retinoid metabolic process, signal transduction, small molecule metabolic process, synapse organization Golgi lumen, basal lamina, cell junction, extracellular matrix, integral to membrane, lysosomal lumen, plasma membrane, synapse calcium ion binding, chondroitin sulfate binding, dystroglycan binding, heparan sulfate proteoglycan binding, laminin binding, protein binding, sialic acid binding, structural constituent of cytoskeleton Human UniProtKB:O15265 AGRP PINC UniProtKB {GO:0008343=GO_REF:0000019, GO:0007631=PMID:9751529, GO:0060259=PMID:15927146, GO:0009755=GO_REF:0000002, GO:0005796=PMID:15927146, GO:0007218=PMID:15927146, GO:0005102=PMID:10318826, GO:0005184=PMID:15927146, GO:0005615=PMID:15927146} O00253 Agouti-related protein protein 20030904 {GO:0008343=IEA, GO:0007631=TAS, GO:0060259=IDA, GO:0009755=IEA, GO:0005796=IDA, GO:0007218=IDA, GO:0005102=TAS, GO:0005184=IDA, GO:0005615=IDA} adult feeding behavior, feeding behavior, hormone-mediated signaling pathway, neuropeptide signaling pathway, regulation of feeding behavior Golgi lumen, extracellular space neuropeptide hormone activity, receptor binding Human AGT BHF-UCL UniProtKB {GO:0030308=GO_REF:0000019, GO:0001658=GO_REF:0000019, GO:0009651=GO_REF:0000019, GO:0009409=GO_REF:0000019, GO:0006883=GO_REF:0000019, GO:0050731=PMID:15652490, GO:0001819=PMID:17906677, GO:0005615=GO_REF:0000024, GO:0001558=PMID:17159080, GO:0051403=GO_REF:0000019, GO:0019229=PMID:17159080, GO:0030162=GO_REF:0000033, GO:0043524=GO_REF:0000019, GO:0002019=PMID:17159080, GO:0002018=PMID:17159080, GO:0030198=GO_REF:0000019, GO:0042127=PMID:17159080, GO:0002016=PMID:17159080, GO:0048169=GO_REF:0000019, GO:0051924=GO_REF:0000019, GO:0061049=GO_REF:0000019, GO:0070371=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0014061=GO_REF:0000019, GO:0045742=PMID:15652490, GO:0010744=PMID:18971559, GO:0007568=GO_REF:0000019, GO:0002034=PMID:10406457, GO:0014068=PMID:15652490, GO:0001543=GO_REF:0000019, GO:0030432=GO_REF:0000019, GO:0051387=PMID:10406457, GO:0010595=PMID:15652490, GO:0032270=PMID:18971559, GO:0010698=PMID:18971559, GO:0034374=PMID:17069818, GO:0005179=GO_REF:0000024, GO:0007186=PMID:10406457, GO:0001999=GO_REF:0000019, GO:0035815=GO_REF:0000019, GO:0001998=GO_REF:0000019, GO:0035813=PMID:17159080, GO:0045893=PMID:15153556, GO:0008083=PMID:10406457, GO:2000379=PMID:17906677, GO:0044267=Reactome:REACT_17015, GO:0051145=GO_REF:0000019, GO:0050663=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0007263=PMID:17159080, GO:0002003=Reactome:REACT_147707, GO:0004867=GO_REF:0000033, GO:0061098=PMID:15153556, GO:0007199=PMID:17159080, GO:0010873=PMID:18971559, GO:0007267=PMID:8513325, GO:0007200=PMID:17159080, GO:0048146=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0007202=GO_REF:0000019, GO:0048143=GO_REF:0000019, GO:0031702=PMID:1378723, GO:0048144=GO_REF:0000019, GO:0031703=PMID:10406457, GO:0035411=GO_REF:0000019, GO:0003331=GO_REF:0000019, GO:0051092=PMID:17906677, GO:0042311=GO_REF:0000019, GO:0040018=GO_REF:0000019, GO:0010613=GO_REF:0000024, GO:0090190=PMID:18607644, GO:0032930=GO_REF:0000019, GO:0033864=PMID:17159080, GO:0014873=GO_REF:0000024, GO:0010535=PMID:15153556, GO:0014824=GO_REF:0000019, GO:0007588=GO_REF:0000019, GO:0043065=PMID:10406457, GO:0001568=GO_REF:0000019, GO:0046622=GO_REF:0000019, GO:0007250=GO_REF:0000019, GO:0001822=PMID:16116425, GO:0045723=GO_REF:0000019, GO:0005576=Reactome:REACT_147891, GO:0006917=GO_REF:0000019, GO:0010951=GO_REF:0000033, GO:0044444=GO_REF:0000019, GO:0048659=GO_REF:0000019, GO:0008065=GO_REF:0000019, GO:0007160=GO_REF:0000019, GO:0001974=PMID:10406457, GO:0050729=PMID:17159080, GO:0034104=GO_REF:0000019, GO:0043410=GO_REF:0000019, GO:0071260=GO_REF:0000019, GO:0003051=GO_REF:0000019} P01019 Angiotensinogen protein 20090115 {GO:0030308=IEA, GO:0001658=IEA, GO:0009651=IEA, GO:0009409=IEA, GO:0006883=IEA, GO:0050731=IDA, GO:0001819=TAS, GO:0005615=ISS, GO:0001558=NAS, GO:0051403=IEA, GO:0019229=NAS, GO:0030162=IBA, GO:0043524=IEA, GO:0002019=NAS, GO:0002018=NAS, GO:0030198=IEA, GO:0042127=NAS, GO:0002016=NAS, GO:0048169=IEA, GO:0051924=IEA, GO:0061049=IEA, GO:0070371=IEA, GO:0044255=TAS, GO:0014061=IEA, GO:0045742=IDA, GO:0010744=IC, GO:0007568=IEA, GO:0002034=TAS, GO:0014068=IDA, GO:0001543=IEA, GO:0030432=IEA, GO:0051387=IDA, GO:0010595=IDA, GO:0032270=IDA, GO:0010698=IDA, GO:0034374=NAS, GO:0005179=ISS, GO:0007186=IDA, GO:0001999=IEA, GO:0035815=IEA, GO:0001998=IEA, GO:0035813=NAS, GO:0045893=IDA, GO:0008083=TAS, GO:2000379=TAS, GO:0044267=TAS, GO:0051145=IEA, GO:0050663=IEA, GO:0008285=IEA, GO:0007263=TAS, GO:0002003=TAS, GO:0004867=IBA, GO:0061098=IMP, GO:0007199=TAS, GO:0010873=IDA, GO:0007267=TAS, GO:0007200=NAS, GO:0048146=ISS, GO:0044281=TAS, GO:0007202=IEA, GO:0048143=IEA, GO:0031702=IPI, GO:0048144=IEA, GO:0031703=IPI, GO:0035411=IEA, GO:0003331=IEA, GO:0051092=TAS, GO:0042311=IEA, GO:0040018=IEA, GO:0010613=ISS, GO:0090190=IDA, GO:0032930=IEA, GO:0033864=TAS, GO:0014873=ISS, GO:0010535=IMP, GO:0014824=IEA, GO:0007588=IEA, GO:0043065=IDA, GO:0001568=IEA, GO:0046622=IEA, GO:0007250=IEA, GO:0001822=IMP, GO:0045723=IEA, GO:0005576=TAS, GO:0006917=IEA, GO:0010951=IBA, GO:0044444=IEA, GO:0048659=IEA, GO:0008065=IEA, GO:0007160=IEA, GO:0001974=TAS, GO:0050729=TAS, GO:0034104=IEA, GO:0043410=IEA, GO:0071260=IEA, GO:0003051=IEA} ERK1 and ERK2 cascade, G-protein coupled receptor signaling pathway, G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger, activation of NF-kappaB-inducing kinase activity, activation of phospholipase C activity, aging, angiotensin maturation, angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure, angiotensin-mediated drinking behavior, artery smooth muscle contraction, astrocyte activation, blood vessel development, blood vessel remodeling, branching involved in ureteric bud morphogenesis, catenin import into nucleus, cell growth involved in cardiac muscle cell development, cell-cell signaling, cell-matrix adhesion, cellular lipid metabolic process, cellular protein metabolic process, cellular response to mechanical stimulus, cellular sodium ion homeostasis, cytokine secretion, establishment of blood-nerve barrier, excretion, extracellular matrix organization, fibroblast proliferation, induction of apoptosis, kidney development, low-density lipoprotein particle remodeling, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of endopeptidase activity, negative regulation of neuron apoptotic process, negative regulation of neurotrophin TRK receptor signaling pathway, negative regulation of tissue remodeling, nitric oxide mediated signal transduction, ovarian follicle rupture, peristalsis, phospholipase C-activating G-protein coupled receptor signaling pathway, positive regulation of MAPK cascade, positive regulation of NAD(P)H oxidase activity, positive regulation of NF-kappaB transcription factor activity, positive regulation of activation of JAK2 kinase activity, positive regulation of apoptotic process, positive regulation of branching involved in ureteric bud morphogenesis, positive regulation of cardiac muscle hypertrophy, positive regulation of cellular protein metabolic process, positive regulation of cholesterol esterification, positive regulation of cytokine production, positive regulation of endothelial cell migration, positive regulation of epidermal growth factor receptor signaling pathway, positive regulation of extracellular matrix constituent secretion, positive regulation of fatty acid biosynthetic process, positive regulation of fibroblast proliferation, positive regulation of inflammatory response, positive regulation of macrophage derived foam cell differentiation, positive regulation of multicellular organism growth, positive regulation of organ growth, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of protein tyrosine kinase activity, positive regulation of reactive oxygen species metabolic process, positive regulation of renal sodium excretion, positive regulation of superoxide anion generation, positive regulation of transcription, DNA-dependent, regulation of blood vessel size by renin-angiotensin, regulation of blood volume by renin-angiotensin, regulation of calcium ion transport, regulation of cell growth, regulation of cell proliferation, regulation of long-term neuronal synaptic plasticity, regulation of norepinephrine secretion, regulation of proteolysis, regulation of renal output by angiotensin, regulation of renal sodium excretion, regulation of vasoconstriction, renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure, renin-angiotensin regulation of aldosterone production, response to cold, response to muscle activity involved in regulation of muscle adaptation, response to salt stress, small molecule metabolic process, smooth muscle cell differentiation, smooth muscle cell proliferation, stress-activated MAPK cascade, vasodilation cytoplasmic part, extracellular region, extracellular space acetyltransferase activator activity, growth factor activity, hormone activity, serine-type endopeptidase inhibitor activity, type 1 angiotensin receptor binding, type 2 angiotensin receptor binding Human AGTPBP1 UniProtKB UniProtKB {GO:0001754=GO_REF:0000024, GO:0035610=GO_REF:0000024, GO:0060041=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0035609=GO_REF:0000024, GO:0005829=GO_REF:0000024, GO:0005739=GO_REF:0000024, GO:0050905=GO_REF:0000024, GO:0015631=GO_REF:0000024, GO:0021772=GO_REF:0000024, GO:0021702=GO_REF:0000024, GO:0006508=GO_REF:0000037, GO:0007628=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0007005=GO_REF:0000024, GO:0042133=GO_REF:0000019, GO:0004181=GO_REF:0000024} Q9UPW5 Cytosolic carboxypeptidase 1 protein 20101123 {GO:0001754=ISS, GO:0035610=ISS, GO:0060041=IEA, GO:0005634=IEA, GO:0035609=ISS, GO:0005829=ISS, GO:0005739=ISS, GO:0050905=ISS, GO:0015631=ISS, GO:0021772=ISS, GO:0021702=ISS, GO:0006508=IEA, GO:0007628=IEA, GO:0008270=IEA, GO:0007005=ISS, GO:0042133=IEA, GO:0004181=ISS} C-terminal protein deglutamylation, adult walking behavior, cerebellar Purkinje cell differentiation, eye photoreceptor cell differentiation, mitochondrion organization, neuromuscular process, neurotransmitter metabolic process, olfactory bulb development, protein side chain deglutamylation, proteolysis, retina development in camera-type eye cytosol, mitochondrion, nucleus metallocarboxypeptidase activity, tubulin binding, zinc ion binding Human UniProtKB:Q641K1 AGTR1 GOC UniProtKB {GO:0005515=PMID:19023134, GO:0004945=PMID:1567413, GO:0019722=PMID:1567413, GO:0005886=Reactome:REACT_22436, GO:0010873=PMID:18971559, GO:0007200=PMID:17159080, GO:0086097=PMID:1378723, GO:0007266=PMID:15611106, GO:0001558=PMID:17159080, GO:0007204=PMID:1567413, GO:0032430=PMID:17069818, GO:0019229=PMID:1378723, GO:0042312=PMID:1378723, GO:0003081=PMID:1378723, GO:0002018=PMID:17159080, GO:0042127=PMID:17159080, GO:0051482=PMID:1567413, GO:0033864=PMID:17159080, GO:0031711=PMID:10993080, GO:0046982=PMID:10993080, GO:0010744=PMID:18971559, GO:0001822=PMID:16116425, GO:0050727=PMID:1378723, GO:0002034=PMID:10993080, GO:0032270=PMID:18971559, GO:0010698=PMID:18971559, GO:0034374=PMID:17069818, GO:0007186=PMID:1378723, GO:0005887=PMID:1378723, GO:0060326=PMID:15635042, GO:0050729=PMID:17159080, GO:0035813=PMID:17159080, GO:0016021=PMID:8135787, GO:2000379=PMID:17159080, GO:0001596=PMID:10993080} P30556 Type-1 angiotensin II receptor protein 20130413 {GO:0005515=IPI, GO:0004945=IDA, GO:0019722=IDA, GO:0005886=TAS, GO:0010873=IMP, GO:0007200=NAS, GO:0086097=IPI, GO:0007266=IDA, GO:0001558=NAS, GO:0007204=IDA, GO:0032430=IMP, GO:0019229=IC, GO:0042312=IC, GO:0003081=IC, GO:0002018=NAS, GO:0042127=NAS, GO:0051482=IDA, GO:0033864=TAS, GO:0031711=IPI, GO:0046982=IPI, GO:0010744=IC, GO:0001822=IMP, GO:0050727=IC, GO:0002034=IC, GO:0032270=IMP, GO:0010698=IMP, GO:0034374=NAS, GO:0007186=IDA, GO:0005887=IC, GO:0060326=IDA, GO:0050729=TAS, GO:0035813=NAS, GO:0016021=NAS, GO:2000379=TAS, GO:0001596=IDA} G-protein coupled receptor signaling pathway, Rho protein signal transduction, calcium-mediated signaling, cell chemotaxis, elevation of cytosolic calcium ion concentration, elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway, kidney development, low-density lipoprotein particle remodeling, phospholipase C-activating G-protein coupled receptor signaling pathway, phospholipase C-activating angiotensin-mediated signaling pathway, positive regulation of NAD(P)H oxidase activity, positive regulation of cellular protein metabolic process, positive regulation of cholesterol esterification, positive regulation of inflammatory response, positive regulation of macrophage derived foam cell differentiation, positive regulation of phospholipase A2 activity, positive regulation of reactive oxygen species metabolic process, regulation of blood vessel size by renin-angiotensin, regulation of cell growth, regulation of cell proliferation, regulation of inflammatory response, regulation of renal sodium excretion, regulation of systemic arterial blood pressure by renin-angiotensin, regulation of vasoconstriction, regulation of vasodilation, renin-angiotensin regulation of aldosterone production integral to membrane, integral to plasma membrane, plasma membrane acetyltransferase activator activity, angiotensin type I receptor activity, angiotensin type II receptor activity, bradykinin receptor binding, protein binding, protein heterodimerization activity Human UniProtKB:P01019 AGTR2 GOC UniProtKB {GO:0005515=PMID:18344519, GO:0030308=PMID:17159080, GO:0004945=PMID:10406457, GO:0021695=GO_REF:0000019, GO:0006883=GO_REF:0000019, GO:0042990=GO_REF:0000019, GO:0007243=PMID:17000928, GO:0001991=GO_REF:0000024, GO:0002018=GO_REF:0000019, GO:0061049=GO_REF:0000019, GO:0007610=PMID:12089445, GO:0072300=GO_REF:0000019, GO:0048019=PMID:17159079, GO:0010459=GO_REF:0000024, GO:0002033=GO_REF:0000019, GO:0010243=GO_REF:0000019, GO:0002035=GO_REF:0000019, GO:0010700=GO_REF:0000019, GO:0051387=PMID:10406457, GO:0007186=PMID:10406457, GO:1900116=PMID:17159079, GO:0007420=PMID:12089445, GO:0005887=PMID:10406457, GO:0051000=PMID:17000928, GO:0035815=GO_REF:0000019, GO:0035566=GO_REF:0000019, GO:0045893=GO_REF:0000019, GO:0043537=PMID:15710780, GO:0008134=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0005886=Reactome:REACT_22289, GO:0007263=PMID:17159080, GO:0007199=PMID:17000928, GO:0048147=GO_REF:0000019, GO:0050715=GO_REF:0000019, GO:0045429=PMID:17000928, GO:0042416=GO_REF:0000019, GO:0006954=GO_REF:0000019, GO:0045909=PMID:17159079, GO:0090190=GO_REF:0000019, GO:0035932=GO_REF:0000019, GO:0043065=PMID:10406457, GO:0005576=PMID:17159079, GO:0001974=PMID:17159080, GO:0008217=PMID:7477266, GO:0032516=PMID:10406457, GO:0017046=GO_REF:0000019, GO:0007166=PMID:10406457, GO:0071549=GO_REF:0000019} P50052 Type-2 angiotensin II receptor protein 20130413 {GO:0005515=IPI, GO:0030308=TAS, GO:0004945=IPI, GO:0021695=IEA, GO:0006883=IEA, GO:0042990=IEA, GO:0007243=ISS, GO:0001991=ISS, GO:0002018=IEA, GO:0061049=IEA, GO:0007610=IMP, GO:0072300=IEA, GO:0048019=TAS, GO:0010459=ISS, GO:0002033=IEA, GO:0010243=IEA, GO:0002035=IEA, GO:0010700=IEA, GO:0051387=IMP, GO:0007186=IC, GO:1900116=TAS, GO:0007420=NAS, GO:0005887=IC, GO:0051000=ISS, GO:0035815=IEA, GO:0035566=IEA, GO:0045893=IEA, GO:0043537=NAS, GO:0008134=IEA, GO:0048471=IEA, GO:0008284=IEA, GO:0005886=TAS, GO:0007263=TAS, GO:0007199=ISS, GO:0048147=IEA, GO:0050715=IEA, GO:0045429=IC, GO:0042416=IEA, GO:0006954=IEA, GO:0045909=IDA, GO:0090190=IEA, GO:0035932=IEA, GO:0043065=IMP, GO:0005576=TAS, GO:0001974=TAS, GO:0008217=TAS, GO:0032516=IDA, GO:0017046=IEA, GO:0007166=IDA, GO:0071549=IEA} G-protein coupled receptor signaling pathway, G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger, aldosterone secretion, behavior, blood vessel remodeling, brain development, brain renin-angiotensin system, cell growth involved in cardiac muscle cell development, cell surface receptor signaling pathway, cellular response to dexamethasone stimulus, cellular sodium ion homeostasis, cerebellar cortex development, dopamine biosynthetic process, extracellular negative regulation of signal transduction, inflammatory response, intracellular protein kinase cascade, negative regulation of blood vessel endothelial cell migration, negative regulation of cell growth, negative regulation of fibroblast proliferation, negative regulation of heart rate, negative regulation of neurotrophin TRK receptor signaling pathway, negative regulation of norepinephrine secretion, nitric oxide mediated signal transduction, positive regulation of apoptotic process, positive regulation of branching involved in ureteric bud morphogenesis, positive regulation of cell proliferation, positive regulation of cytokine secretion, positive regulation of metanephric glomerulus development, positive regulation of nitric oxide biosynthetic process, positive regulation of nitric-oxide synthase activity, positive regulation of phosphoprotein phosphatase activity, positive regulation of renal sodium excretion, positive regulation of transcription, DNA-dependent, positive regulation of vasodilation, regulation of blood pressure, regulation of metanephros size, regulation of systemic arterial blood pressure by circulatory renin-angiotensin, regulation of transcription factor import into nucleus, renin-angiotensin regulation of aldosterone production, response to organic nitrogen, vasodilation by angiotensin involved in regulation of systemic arterial blood pressure extracellular region, integral to plasma membrane, perinuclear region of cytoplasm, plasma membrane angiotensin type II receptor activity, peptide hormone binding, protein binding, receptor antagonist activity, transcription factor binding Human AGTRAP HPA UniProtKB {GO:0005515=PMID:19060904, GO:0001666=GO_REF:0000019, GO:0004945=GO_REF:0000019, GO:0000139=GO_REF:0000039, GO:0005886=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0008217=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0005938=GO_REF:0000019, GO:0030659=GO_REF:0000039, GO:0043231=GO_REF:0000052} Q6RW13 Type-1 angiotensin II receptor-associated protein protein 20111111 {GO:0005515=IPI, GO:0001666=IEA, GO:0004945=IEA, GO:0000139=IEA, GO:0005886=IEA, GO:0005789=IEA, GO:0008217=IEA, GO:0016021=IEA, GO:0005938=IEA, GO:0030659=IEA, GO:0043231=IDA} regulation of blood pressure, response to hypoxia Golgi membrane, cell cortex, cytoplasmic vesicle membrane, endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle, plasma membrane angiotensin type II receptor activity, protein binding Human AGXT HGNC UniProtKB {GO:0005515=PMID:15911627, GO:0046724=GO_REF:0000019, GO:0006625=PMID:1703535, GO:0005782=Reactome:REACT_16972, GO:0005102=PMID:20178365, GO:0008483=PMID:20133649, GO:0051384=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0051591=GO_REF:0000019, GO:0042803=PMID:12899834, GO:0019265=PMID:22198249, GO:0008453=Reactome:REACT_16972, GO:0034641=Reactome:REACT_13, GO:0005759=GO_REF:0000039, GO:0030170=PMID:15802217, GO:0042853=PMID:17696873, GO:0046487=PMID:3709805, GO:0042866=GO_REF:0000019, GO:0009436=PMID:22198249, GO:0019448=PMID:18492492, GO:0004760=GO_REF:0000003, GO:0005777=PMID:7813517} P21549 Serine--pyruvate aminotransferase protein 20061208 {GO:0005515=IPI, GO:0046724=IEA, GO:0006625=IMP, GO:0005782=TAS, GO:0005102=IPI, GO:0008483=IDA, GO:0051384=IEA, GO:0044281=TAS, GO:0051591=IEA, GO:0042803=IDA, GO:0019265=IDA, GO:0008453=TAS, GO:0034641=TAS, GO:0005759=IEA, GO:0030170=IMP, GO:0042853=IDA, GO:0046487=IMP, GO:0042866=IEA, GO:0009436=IDA, GO:0019448=IDA, GO:0004760=IEA, GO:0005777=IDA} L-alanine catabolic process, L-cysteine catabolic process, cellular nitrogen compound metabolic process, glycine biosynthetic process, by transamination of glyoxylate, glyoxylate catabolic process, glyoxylate metabolic process, oxalic acid secretion, protein targeting to peroxisome, pyruvate biosynthetic process, response to cAMP, response to glucocorticoid stimulus, small molecule metabolic process mitochondrial matrix, peroxisomal matrix, peroxisome alanine-glyoxylate transaminase activity, protein binding, protein homodimerization activity, pyridoxal phosphate binding, receptor binding, serine-pyruvate transaminase activity, transaminase activity Human AGXT2 BHF-UCL UniProtKB {GO:0016223=GO_REF:0000019, GO:0008483=GO_REF:0000002, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0019265=PMID:20018850, GO:0008453=Reactome:REACT_25087, GO:0045429=PMID:20018850, GO:0005739=PMID:20018850, GO:0034641=Reactome:REACT_13, GO:0046135=Reactome:REACT_1023, GO:0005759=Reactome:REACT_25087, GO:0019481=PMID:20018850, GO:0030170=GO_REF:0000002, GO:0047305=GO_REF:0000003, GO:0046487=Reactome:REACT_16925, GO:0009436=PMID:20018850, GO:0006206=Reactome:REACT_957} Q9BYV1 Alanine--glyoxylate aminotransferase 2, mitochondrial protein 20120523 {GO:0016223=IEA, GO:0008483=IEA, GO:0055086=TAS, GO:0044281=TAS, GO:0019265=IDA, GO:0008453=TAS, GO:0045429=IDA, GO:0005739=IDA, GO:0034641=TAS, GO:0046135=TAS, GO:0005759=TAS, GO:0019481=IDA, GO:0030170=IEA, GO:0047305=IEA, GO:0046487=TAS, GO:0009436=IDA, GO:0006206=TAS} L-alanine catabolic process, by transamination, cellular nitrogen compound metabolic process, glycine biosynthetic process, by transamination of glyoxylate, glyoxylate catabolic process, glyoxylate metabolic process, nucleobase-containing small molecule metabolic process, positive regulation of nitric oxide biosynthetic process, pyrimidine nucleobase metabolic process, pyrimidine nucleoside catabolic process, small molecule metabolic process mitochondrial matrix, mitochondrion (R)-3-amino-2-methylpropionate-pyruvate transaminase activity, alanine-glyoxylate transaminase activity, beta-alanine-pyruvate transaminase activity, pyridoxal phosphate binding, transaminase activity Human AGXT2L1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0006520=GO_REF:0000029, GO:0030170=GO_REF:0000002, GO:0050459=GO_REF:0000003, GO:0008483=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0008453=GO_REF:0000029} Q8TBG4 Ethanolamine-phosphate phospho-lyase protein 20070906 {GO:0005739=IEA, GO:0006520=NAS, GO:0030170=IEA, GO:0050459=IEA, GO:0008483=IEA, GO:0005575=ND, GO:0008453=NAS} cellular amino acid metabolic process cellular_component, mitochondrion alanine-glyoxylate transaminase activity, ethanolamine-phosphate phospho-lyase activity, pyridoxal phosphate binding, transaminase activity Human AGXT2L2 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0030170=GO_REF:0000002, GO:0008483=GO_REF:0000037, GO:0016829=GO_REF:0000037} Q8IUZ5 5-phosphohydroxy-L-lysine phospho-lyase protein 20130413 {GO:0005739=IEA, GO:0030170=IEA, GO:0008483=IEA, GO:0016829=IEA} mitochondrion lyase activity, pyridoxal phosphate binding, transaminase activity Human UniProtKB-SubCell:SL-0173 AHCTF1 HPA UniProtKB {GO:0000236=Reactome:REACT_682, GO:0031965=GO_REF:0000052, GO:0003700=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0015031=GO_REF:0000037, GO:0051292=PMID:17098863, GO:0003677=GO_REF:0000037, GO:0016363=GO_REF:0000039, GO:0005829=Reactome:REACT_150414, GO:0000910=PMID:17098863, GO:0005737=GO_REF:0000019, GO:0005643=PMID:17098863, GO:0000087=Reactome:REACT_910, GO:0031080=PMID:17098863, GO:0000777=PMID:17098863, GO:0005654=GO_REF:0000039, GO:0051028=GO_REF:0000037, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0000785=PMID:17098863} Q8WYP5 Protein ELYS protein 20101115 {GO:0000236=TAS, GO:0031965=IDA, GO:0003700=IEA, GO:0005634=IDA, GO:0015031=IEA, GO:0051292=IMP, GO:0003677=IEA, GO:0016363=IEA, GO:0005829=TAS, GO:0000910=IMP, GO:0005737=IEA, GO:0005643=IDA, GO:0000087=TAS, GO:0031080=IDA, GO:0000777=IDA, GO:0005654=IEA, GO:0051028=IEA, GO:0000278=TAS, GO:0000090=TAS, GO:0000785=IDA} M phase of mitotic cell cycle, cytokinesis, mRNA transport, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, nuclear pore complex assembly, protein transport chromatin, condensed chromosome kinetochore, cytoplasm, cytosol, nuclear matrix, nuclear membrane, nuclear pore, nuclear pore outer ring, nucleoplasm, nucleus DNA binding, sequence-specific DNA binding transcription factor activity Human AHCY Reactome UniProtKB {GO:0004013=Reactome:REACT_6756, GO:0034641=Reactome:REACT_13, GO:0042470=GO_REF:0000039, GO:0005737=GO_REF:0000029, GO:0006805=Reactome:REACT_13433, GO:0000096=Reactome:REACT_115639, GO:0044281=Reactome:REACT_111217, GO:0032259=Reactome:REACT_6946, GO:0006730=GO_REF:0000029, GO:0005829=Reactome:REACT_6756} P23526 Adenosylhomocysteinase protein 20130213 {GO:0004013=TAS, GO:0034641=TAS, GO:0042470=IEA, GO:0005737=NAS, GO:0006805=TAS, GO:0000096=TAS, GO:0044281=TAS, GO:0032259=TAS, GO:0006730=NAS, GO:0005829=TAS} cellular nitrogen compound metabolic process, methylation, one-carbon metabolic process, small molecule metabolic process, sulfur amino acid metabolic process, xenobiotic metabolic process cytoplasm, cytosol, melanosome adenosylhomocysteinase activity Human AHCYL1 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0004013=GO_REF:0000003, GO:0006378=GO_REF:0000019, GO:0044070=GO_REF:0000019, GO:0005783=GO_REF:0000039, GO:0010765=GO_REF:0000019, GO:0006611=GO_REF:0000019, GO:0031440=GO_REF:0000019, GO:0006730=GO_REF:0000037, GO:0032412=GO_REF:0000019} O43865 Putative adenosylhomocysteinase 2 protein 20130415 {GO:0005515=IPI, GO:0004013=IEA, GO:0006378=IEA, GO:0044070=IEA, GO:0005783=IEA, GO:0010765=IEA, GO:0006611=IEA, GO:0031440=IEA, GO:0006730=IEA, GO:0032412=IEA} mRNA polyadenylation, one-carbon metabolic process, positive regulation of sodium ion transport, protein export from nucleus, regulation of anion transport, regulation of ion transmembrane transporter activity, regulation of mRNA 3'-end processing endoplasmic reticulum adenosylhomocysteinase activity, protein binding Human UniProtKB:P04608 AHCYL2 UniProtKB UniProtKB {GO:0004013=GO_REF:0000003, GO:0006730=GO_REF:0000037} Q96HN2 Putative adenosylhomocysteinase 3 protein 20130413 {GO:0004013=IEA, GO:0006730=IEA} one-carbon metabolic process adenosylhomocysteinase activity Human EC:3.3.1.1 AHDC1 UniProtKB UniProtKB {GO:0003677=GO_REF:0000037} Q5TGY3 AT-hook DNA-binding motif-containing protein 1 protein 20130413 {GO:0003677=IEA} DNA binding Human UniProtKB-KW:KW-0238 AHI1 IntAct UniProtKB {GO:0005515=PMID:22623184, GO:0036038=GO_REF:0000024, GO:0070986=GO_REF:0000024, GO:0001738=GO_REF:0000024, GO:0035844=GO_REF:0000024, GO:0001947=GO_REF:0000024, GO:0035845=GO_REF:0000024, GO:0045944=GO_REF:0000024, GO:0039008=GO_REF:0000024, GO:0016192=GO_REF:0000024, GO:0043066=GO_REF:0000024, GO:0033365=GO_REF:0000019, GO:0005814=GO_REF:0000024, GO:0071599=GO_REF:0000024, GO:0039023=GO_REF:0000024, GO:0031513=GO_REF:0000024, GO:0010842=GO_REF:0000024, GO:0007417=GO_REF:0000024, GO:0070121=GO_REF:0000024, GO:0065001=GO_REF:0000024, GO:0005929=GO_REF:0000024, GO:0042384=GO_REF:0000024, GO:0050795=GO_REF:0000024, GO:0060271=GO_REF:0000024, GO:0030862=GO_REF:0000024, GO:0034613=GO_REF:0000024, GO:0030902=GO_REF:0000024, GO:0007169=GO_REF:0000024, GO:0002092=GO_REF:0000024} Q8N157 Jouberin protein 20130415 {GO:0005515=IPI, GO:0036038=ISS, GO:0070986=ISS, GO:0001738=ISS, GO:0035844=ISS, GO:0001947=ISS, GO:0035845=ISS, GO:0045944=ISS, GO:0039008=ISS, GO:0016192=ISS, GO:0043066=ISS, GO:0033365=IEA, GO:0005814=ISS, GO:0071599=ISS, GO:0039023=ISS, GO:0031513=ISS, GO:0010842=ISS, GO:0007417=ISS, GO:0070121=ISS, GO:0065001=ISS, GO:0005929=ISS, GO:0042384=ISS, GO:0050795=ISS, GO:0060271=ISS, GO:0030862=ISS, GO:0034613=ISS, GO:0030902=ISS, GO:0007169=ISS, GO:0002092=ISS} Kupffer's vesicle development, cellular protein localization, central nervous system development, cilium assembly, cilium morphogenesis, cloaca development, heart looping, hindbrain development, left/right axis specification, morphogenesis of a polarized epithelium, negative regulation of apoptotic process, otic vesicle development, photoreceptor cell outer segment organization, positive regulation of polarized epithelial cell differentiation, positive regulation of receptor internalization, positive regulation of transcription from RNA polymerase II promoter, pronephric duct morphogenesis, pronephric nephron tubule morphogenesis, protein localization to organelle, regulation of behavior, retina layer formation, specification of axis polarity, transmembrane receptor protein tyrosine kinase signaling pathway, vesicle-mediated transport TCTN-B9D complex, centriole, cilium, nonmotile primary cilium protein binding Human UniProtKB:P50570 AHNAK UniProtKB UniProtKB {GO:0005515=PMID:16417406, GO:0005634=PMID:1608957, GO:0007399=GO_REF:0000029} Q09666 Neuroblast differentiation-associated protein AHNAK protein 20101006 {GO:0005515=IPI, GO:0005634=NAS, GO:0007399=NAS} nervous system development nucleus protein binding Human UniProtKB:P55160 AHNAK2 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039} Q8IVF2 Protein AHNAK2 protein 20130413 {GO:0005634=IEA} nucleus Human UniProtKB-SubCell:SL-0191 AHR GOC UniProtKB {GO:0005515=PMID:9079689, GO:0010468=PMID:15681594, GO:0003700=PMID:11782478, GO:0006805=PMID:19538249, GO:0044212=PMID:15681594, GO:0006366=PMID:10395741, GO:0045899=GO_REF:0000019, GO:0003705=GO_REF:0000019, GO:0051879=PMID:9079689, GO:0005634=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0046983=PMID:19538249, GO:0030850=GO_REF:0000019, GO:0004879=PMID:10395741, GO:0009410=PMID:7961644, GO:0005667=PMID:19538249, GO:0006355=PMID:10395741, GO:0001568=PMID:19538249, GO:0006357=PMID:15681594, GO:0046982=PMID:19538249, GO:0005730=GO_REF:0000052, GO:0006950=PMID:7961644, GO:0006915=PMID:12213388, GO:0030888=PMID:15681594, GO:0000122=GO_REF:0000019, GO:0003677=PMID:19538249, GO:0043565=GO_REF:0000019, GO:0007049=PMID:12213388, GO:0034752=PMID:19538249, GO:0030522=PMID:10395741, GO:0008134=PMID:9079689} P35869 Aryl hydrocarbon receptor protein 20130413 {GO:0005515=IPI, GO:0010468=IDA, GO:0003700=IDA, GO:0006805=TAS, GO:0044212=IDA, GO:0006366=IDA, GO:0045899=IEA, GO:0003705=IEA, GO:0051879=IDA, GO:0005634=IDA, GO:0005737=IDA, GO:0046983=TAS, GO:0030850=IEA, GO:0004879=IDA, GO:0009410=IDA, GO:0005667=TAS, GO:0006355=IDA, GO:0001568=NAS, GO:0006357=IDA, GO:0046982=TAS, GO:0005730=IDA, GO:0006950=IDA, GO:0006915=TAS, GO:0030888=IDA, GO:0000122=IEA, GO:0003677=TAS, GO:0043565=IEA, GO:0007049=TAS, GO:0034752=TAS, GO:0030522=IDA, GO:0008134=IPI} apoptotic process, blood vessel development, cell cycle, intracellular receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, positive regulation of RNA polymerase II transcriptional preinitiation complex assembly, prostate gland development, regulation of B cell proliferation, regulation of gene expression, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, response to stress, response to xenobiotic stimulus, transcription from RNA polymerase II promoter, xenobiotic metabolic process cytoplasm, cytosolic aryl hydrocarbon receptor complex, nucleolus, nucleus, transcription factor complex DNA binding, Hsp90 protein binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, protein binding, protein dimerization activity, protein heterodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding Human AHRR InterPro UniProtKB {GO:0005737=GO_REF:0000039, GO:0033235=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0004871=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} G3V143 Aryl hydrocarbon receptor repressor protein 20130413 {GO:0005737=IEA, GO:0033235=IEA, GO:0046983=IEA, GO:0005634=IEA, GO:0000122=IEA, GO:0004871=IEA, GO:0003677=IEA, GO:0006351=IEA} negative regulation of transcription from RNA polymerase II promoter, positive regulation of protein sumoylation, transcription, DNA-dependent cytoplasm, nucleus DNA binding, protein dimerization activity, signal transducer activity Human InterPro:IPR011598 AHSA1 GOC UniProtKB {GO:0005515=PMID:19875381, GO:0005737=GO_REF:0000052, GO:0006457=GO_REF:0000024, GO:0005783=GO_REF:0000039, GO:0006950=GO_REF:0000024, GO:0051087=PMID:12504007, GO:0032781=PMID:12504007, GO:0001671=PMID:12504007, GO:0005829=GO_REF:0000039} O95433 Activator of 90 kDa heat shock protein ATPase homolog 1 protein 20130413 {GO:0005515=IPI, GO:0005737=IDA, GO:0006457=ISS, GO:0005783=IEA, GO:0006950=ISS, GO:0051087=IDA, GO:0032781=IDA, GO:0001671=IDA, GO:0005829=IEA} positive regulation of ATPase activity, protein folding, response to stress cytoplasm, cytosol, endoplasmic reticulum ATPase activator activity, chaperone binding, protein binding Human AHSA2 UniProtKB UniProtKB {GO:0006950=GO_REF:0000037, GO:0051087=GO_REF:0000002, GO:0001671=GO_REF:0000002} Q719I0 Activator of 90 kDa heat shock protein ATPase homolog 2 protein 20130413 {GO:0006950=IEA, GO:0051087=IEA, GO:0001671=IEA} response to stress ATPase activator activity, chaperone binding Human UniProtKB-KW:KW-0346 AHSG GOC UniProtKB {GO:0030500=PMID:3474608, GO:0006907=PMID:12773197, GO:0004869=GO_REF:0000002, GO:0019210=PMID:12203945, GO:0046627=PMID:12153747, GO:0050727=PMID:12642050, GO:0005576=PMID:14718574, GO:0006953=PMID:12153747, GO:0030502=GO_REF:0000024, GO:0005615=PMID:11922920, GO:0042326=PMID:12203945, GO:0050766=PMID:12725640, GO:0001501=PMID:12153747, GO:0001503=GO_REF:0000019} P02765 Alpha-2-HS-glycoprotein protein 20130413 {GO:0030500=NAS, GO:0006907=NAS, GO:0004869=IEA, GO:0019210=NAS, GO:0046627=NAS, GO:0050727=IMP, GO:0005576=NAS, GO:0006953=IDA, GO:0030502=ISS, GO:0005615=NAS, GO:0042326=NAS, GO:0050766=IDA, GO:0001501=NAS, GO:0001503=IEA} acute-phase response, negative regulation of bone mineralization, negative regulation of insulin receptor signaling pathway, negative regulation of phosphorylation, ossification, pinocytosis, positive regulation of phagocytosis, regulation of bone mineralization, regulation of inflammatory response, skeletal system development extracellular region, extracellular space cysteine-type endopeptidase inhibitor activity, kinase inhibitor activity Human AHSP UniProtKB UniProtKB {GO:0030097=PMID:12066189, GO:0030492=PMID:12066189, GO:0020027=PMID:12066189, GO:0005833=PMID:12066189, GO:0006457=GO_REF:0000002, GO:0050821=GO_REF:0000002, GO:0051082=PMID:12066189} Q9NZD4 Alpha-hemoglobin-stabilizing protein protein 20040806 {GO:0030097=NAS, GO:0030492=NAS, GO:0020027=NAS, GO:0005833=NAS, GO:0006457=IEA, GO:0050821=IEA, GO:0051082=NAS} hemoglobin metabolic process, hemopoiesis, protein folding, protein stabilization hemoglobin complex hemoglobin binding, unfolded protein binding Human AICDA IntAct UniProtKB {GO:0016814=GO_REF:0000002, GO:0006397=GO_REF:0000037, GO:0005515=PMID:21722948, GO:0045190=GO_REF:0000019, GO:0005634=PMID:14769937, GO:0016445=PMID:18722174, GO:0090310=PMID:21496894, GO:0000178=PMID:21255825, GO:0005737=GO_REF:0000054, GO:0071222=GO_REF:0000019, GO:0030183=PMID:11007475, GO:0080111=PMID:21496894, GO:0004126=PMID:18722174, GO:0008270=GO_REF:0000002} Q9GZX7 Activation-induced cytidine deaminase protein 20130415 {GO:0016814=IEA, GO:0006397=IEA, GO:0005515=IPI, GO:0045190=IEA, GO:0005634=IDA, GO:0016445=IDA, GO:0090310=IDA, GO:0000178=IDA, GO:0005737=IDA, GO:0071222=IEA, GO:0030183=NAS, GO:0080111=IDA, GO:0004126=IDA, GO:0008270=IEA} B cell differentiation, DNA demethylation, cellular response to lipopolysaccharide, isotype switching, mRNA processing, negative regulation of methylation-dependent chromatin silencing, somatic diversification of immunoglobulins cytoplasm, exosome (RNase complex), nucleus cytidine deaminase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines, protein binding, zinc ion binding Human UniProtKB:Q13569 AIDA MGI UniProtKB {GO:0043496=GO_REF:0000024, GO:0044444=GO_REF:0000019, GO:0046329=GO_REF:0000024, GO:0019904=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0009953=GO_REF:0000024, GO:0043508=PMID:17681137} Q96BJ3 Axin interactor, dorsalization-associated protein protein 20110406 {GO:0043496=ISS, GO:0044444=IEA, GO:0046329=ISS, GO:0019904=IEA, GO:0005575=ND, GO:0009953=ISS, GO:0043508=IDA} dorsal/ventral pattern formation, negative regulation of JNK cascade, negative regulation of JUN kinase activity, regulation of protein homodimerization activity cellular_component, cytoplasmic part protein domain specific binding Human AIF1 InterPro UniProtKB {GO:2000406=PMID:16049345, GO:1900087=PMID:15117732, GO:0005884=PMID:18699778, GO:0005509=GO_REF:0000002, GO:0032587=PMID:18699778, GO:0001891=GO_REF:0000024, GO:0005634=PMID:22116621, GO:0006911=GO_REF:0000024, GO:0030027=GO_REF:0000024, GO:0005829=PMID:22116621, GO:0003674=GO_REF:0000015, GO:0016601=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0051015=PMID:16049345, GO:0006954=GO_REF:0000024, GO:0071346=GO_REF:0000024, GO:0042102=PMID:16049345, GO:0030041=PMID:16049345, GO:0097178=PMID:17011575, GO:0090026=PMID:15117732, GO:0001774=PMID:17011575, GO:0051017=PMID:18699778} Q5STX8 Allograft inflammatory factor 1 protein 20130413 {GO:2000406=IDA, GO:1900087=IDA, GO:0005884=IDA, GO:0005509=IEA, GO:0032587=IDA, GO:0001891=ISS, GO:0005634=IDA, GO:0006911=ISS, GO:0030027=ISS, GO:0005829=IDA, GO:0003674=ND, GO:0016601=ISS, GO:0005737=ISS, GO:0051015=IDA, GO:0006954=ISS, GO:0071346=ISS, GO:0042102=IDA, GO:0030041=IDA, GO:0097178=NAS, GO:0090026=IDA, GO:0001774=NAS, GO:0051017=IDA} Rac protein signal transduction, actin filament bundle assembly, actin filament polymerization, cellular response to interferon-gamma, inflammatory response, microglial cell activation, phagocytosis, engulfment, positive regulation of G1/S transition of mitotic cell cycle, positive regulation of T cell migration, positive regulation of T cell proliferation, positive regulation of monocyte chemotaxis, ruffle assembly actin filament, cytoplasm, cytosol, lamellipodium, nucleus, phagocytic cup, ruffle membrane actin filament binding, calcium ion binding, molecular_function Human InterPro:IPR002048|InterPro:IPR011992 AIF1L LIFEdb UniProtKB {GO:0043234=GO_REF:0000019, GO:0005737=GO_REF:0000037, GO:0051015=PMID:18699778, GO:0005884=PMID:18699778, GO:0005509=GO_REF:0000002, GO:0032587=GO_REF:0000039, GO:0015629=GO_REF:0000054, GO:0005925=GO_REF:0000054} Q9BQI0 Allograft inflammatory factor 1-like protein 20100607 {GO:0043234=IEA, GO:0005737=IEA, GO:0051015=IDA, GO:0005884=IDA, GO:0005509=IEA, GO:0032587=IEA, GO:0015629=IDA, GO:0005925=IDA} actin cytoskeleton, actin filament, cytoplasm, focal adhesion, protein complex, ruffle membrane actin filament binding, calcium ion binding Human AIFM1 IntAct UniProtKB {GO:0005515=PMID:22371500, GO:0048471=GO_REF:0000039, GO:0006919=PMID:17094969, GO:0050660=GO_REF:0000002, GO:0005743=GO_REF:0000039, GO:0009055=PMID:9989411, GO:0005634=GO_REF:0000024, GO:0051402=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0005829=GO_REF:0000024, GO:0005739=PMID:9989411, GO:0005758=PMID:15775970, GO:0006309=GO_REF:0000019, GO:0070059=GO_REF:0000024, GO:0016491=GO_REF:0000037, GO:0045454=GO_REF:0000002} O95831 Apoptosis-inducing factor 1, mitochondrial protein 20130415 {GO:0005515=IPI, GO:0048471=IEA, GO:0006919=IDA, GO:0050660=IEA, GO:0005743=IEA, GO:0009055=TAS, GO:0005634=ISS, GO:0051402=IEA, GO:0003677=IEA, GO:0005829=ISS, GO:0005739=TAS, GO:0005758=IDA, GO:0006309=IEA, GO:0070059=ISS, GO:0016491=IEA, GO:0045454=IEA} activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic DNA fragmentation, cell redox homeostasis, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, neuron apoptotic process cytosol, mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrion, nucleus, perinuclear region of cytoplasm DNA binding, electron carrier activity, flavin adenine dinucleotide binding, oxidoreductase activity, protein binding Human UniProtKB:Q63ZY3-2 AIFM2 MGI UniProtKB {GO:0005739=PMID:11980907, GO:0005737=PMID:12135761, GO:0008637=PMID:11980907, GO:0030261=PMID:11980907, GO:0004174=PMID:15958387, GO:0050660=PMID:15958387, GO:0005741=PMID:11980907, GO:0006917=PMID:11980907, GO:0016021=GO_REF:0000037, GO:0003677=PMID:15958387, GO:0005829=PMID:11980907} Q9BRQ8 Apoptosis-inducing factor 2 protein 20060110 {GO:0005739=IDA, GO:0005737=IDA, GO:0008637=NAS, GO:0030261=IDA, GO:0004174=IDA, GO:0050660=IDA, GO:0005741=IDA, GO:0006917=IDA, GO:0016021=IEA, GO:0003677=IDA, GO:0005829=IDA} apoptotic mitochondrial changes, chromosome condensation, induction of apoptosis cytoplasm, cytosol, integral to membrane, mitochondrial outer membrane, mitochondrion DNA binding, electron-transferring-flavoprotein dehydrogenase activity, flavin adenine dinucleotide binding Human AIFM3 HPA UniProtKB {GO:0008635=PMID:15764604, GO:0005886=PMID:15764604, GO:0051537=GO_REF:0000037, GO:0005783=PMID:15764604, GO:0050660=GO_REF:0000002, GO:0005743=PMID:15764604, GO:0005634=PMID:15764604, GO:0006917=PMID:15764604, GO:0008656=PMID:15764604, GO:0046872=GO_REF:0000037, GO:0051882=PMID:15764604, GO:0005829=PMID:15764604, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0016491=GO_REF:0000037, GO:0045454=GO_REF:0000002, GO:0022900=GO_REF:0000037} Q96NN9 Apoptosis-inducing factor 3 protein 20101115 {GO:0008635=IDA, GO:0005886=IDA, GO:0051537=IEA, GO:0005783=IDA, GO:0050660=IEA, GO:0005743=IDA, GO:0005634=IDA, GO:0006917=IDA, GO:0008656=IDA, GO:0046872=IEA, GO:0051882=IDA, GO:0005829=IDA, GO:0005739=IDA, GO:0005737=IDA, GO:0016491=IEA, GO:0045454=IEA, GO:0022900=IEA} activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c, cell redox homeostasis, electron transport chain, induction of apoptosis, mitochondrial depolarization cytoplasm, cytosol, endoplasmic reticulum, mitochondrial inner membrane, mitochondrion, nucleus, plasma membrane 2 iron, 2 sulfur cluster binding, cysteine-type endopeptidase activator activity involved in apoptotic process, flavin adenine dinucleotide binding, metal ion binding, oxidoreductase activity Human AIG1 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0016021=GO_REF:0000037} Q9NVV5 Androgen-induced gene 1 protein protein 20130415 {GO:0005515=IPI, GO:0016021=IEA} integral to membrane protein binding Human UniProtKB:Q96PM5 AIM1 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q9Y4K1 Absent in melanoma 1 protein protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human AIM1L null null {} null null null null {} null null null AIM2 HPA UniProtKB {GO:0005515=PMID:22286270, GO:2001056=GO_REF:0000019, GO:0035458=GO_REF:0000019, GO:0032731=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0002218=GO_REF:0000019, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_75821, GO:0042802=GO_REF:0000019, GO:0005739=GO_REF:0000052, GO:0005737=PMID:19158679, GO:0006955=PMID:9242382, GO:0003690=GO_REF:0000019, GO:0051092=PMID:19158675, GO:0006954=GO_REF:0000037, GO:0050718=PMID:19158679, GO:0032461=PMID:19158676, GO:0050702=PMID:19158679, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0032088=PMID:16432157, GO:0035690=PMID:19158679, GO:0070269=GO_REF:0000019, GO:0033209=PMID:16432157, GO:0044444=PMID:19158679, GO:0002230=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0097169=PMID:19158676} Q5T3W0 Interferon-inducible protein AIM2 protein 20101115 {GO:0005515=IPI, GO:2001056=IEA, GO:0035458=IEA, GO:0032731=IEA, GO:0005634=IDA, GO:0002218=IEA, GO:0035872=TAS, GO:0005829=TAS, GO:0042802=IEA, GO:0005739=IDA, GO:0005737=IDA, GO:0006955=TAS, GO:0003690=IEA, GO:0051092=IDA, GO:0006954=IEA, GO:0050718=IDA, GO:0032461=IDA, GO:0050702=IMP, GO:0005730=IDA, GO:0006915=IEA, GO:0032088=IDA, GO:0035690=IDA, GO:0070269=IEA, GO:0033209=IDA, GO:0044444=IDA, GO:0002230=IEA, GO:0045087=TAS, GO:0097169=IDA} activation of innate immune response, apoptotic process, cellular response to drug, cellular response to interferon-beta, immune response, inflammatory response, innate immune response, interleukin-1 beta secretion, negative regulation of NF-kappaB transcription factor activity, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, positive regulation of NF-kappaB transcription factor activity, positive regulation of cysteine-type endopeptidase activity, positive regulation of defense response to virus by host, positive regulation of interleukin-1 beta production, positive regulation of interleukin-1 beta secretion, positive regulation of protein oligomerization, pyroptosis, tumor necrosis factor-mediated signaling pathway AIM2 inflammasome complex, cytoplasm, cytoplasmic part, cytosol, mitochondrion, nucleolus, nucleus double-stranded DNA binding, identical protein binding, protein binding Human AIMP1 IntAct UniProtKB {GO:0030133=GO_REF:0000039, GO:0005515=PMID:22190034, GO:0010467=Reactome:REACT_71, GO:0043498=PMID:11741979, GO:0005783=GO_REF:0000039, GO:0007267=PMID:11741979, GO:0005634=GO_REF:0000039, GO:0050900=PMID:11306575, GO:0005615=GO_REF:0000037, GO:0017101=PMID:14500886, GO:0042803=PMID:11306575, GO:0005829=Reactome:REACT_15516, GO:0006954=GO_REF:0000037, GO:0006935=PMID:7545917, GO:0006006=GO_REF:0000037, GO:0007155=GO_REF:0000037, GO:0005794=GO_REF:0000039, GO:0000049=PMID:11306575, GO:0009611=PMID:7545917, GO:0006915=GO_REF:0000037, GO:0001525=GO_REF:0000037, GO:0005125=PMID:11306575, GO:0006418=Reactome:REACT_15482, GO:0007165=PMID:9405472, GO:0001937=PMID:11741979} Q12904 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 protein 20130415 {GO:0030133=IEA, GO:0005515=IPI, GO:0010467=TAS, GO:0043498=IDA, GO:0005783=IEA, GO:0007267=IDA, GO:0005634=IEA, GO:0050900=IDA, GO:0005615=IEA, GO:0017101=IDA, GO:0042803=IDA, GO:0005829=TAS, GO:0006954=IEA, GO:0006935=TAS, GO:0006006=IEA, GO:0007155=IEA, GO:0005794=IEA, GO:0000049=IDA, GO:0009611=TAS, GO:0006915=IEA, GO:0001525=IEA, GO:0005125=ISS, GO:0006418=TAS, GO:0007165=NAS, GO:0001937=IDA} angiogenesis, apoptotic process, cell adhesion, cell-cell signaling, chemotaxis, gene expression, glucose metabolic process, inflammatory response, leukocyte migration, negative regulation of endothelial cell proliferation, response to wounding, signal transduction, tRNA aminoacylation for protein translation Golgi apparatus, aminoacyl-tRNA synthetase multienzyme complex, cytosol, endoplasmic reticulum, extracellular space, nucleus, transport vesicle cell surface binding, cytokine activity, protein binding, protein homodimerization activity, tRNA binding Human UniProtKB:P04591:PRO_0000038593 AIMP2 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0010467=Reactome:REACT_71, GO:0008285=GO_REF:0000019, GO:0031398=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0060510=GO_REF:0000019, GO:0006418=Reactome:REACT_15482, GO:0005829=Reactome:REACT_15516} Q13155 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0008285=IEA, GO:0031398=IEA, GO:0006915=IEA, GO:0005634=IEA, GO:0060510=IEA, GO:0006418=TAS, GO:0005829=TAS} Type II pneumocyte differentiation, apoptotic process, gene expression, negative regulation of cell proliferation, positive regulation of protein ubiquitination, tRNA aminoacylation for protein translation cytosol, nucleus protein binding Human UniProtKB:P04591:PRO_0000038593 AIP GOC UniProtKB {GO:0005515=PMID:21903422, GO:0006805=GO_REF:0000019, GO:0005886=PMID:17329248, GO:0006626=PMID:14557246, GO:0051344=GO_REF:0000019, GO:0003713=PMID:9447995, GO:0003755=GO_REF:0000038, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0010738=GO_REF:0000019, GO:0022417=PMID:14557246, GO:0005829=PMID:14557246, GO:0044445=GO_REF:0000019, GO:0007165=PMID:9111057, GO:0005737=GO_REF:0000052, GO:0006457=GO_REF:0000038, GO:0051082=PMID:14557246, GO:0004871=PMID:9111057, GO:0036004=PMID:17329248, GO:0008134=PMID:9447995} O00170 AH receptor-interacting protein protein 20130413 {GO:0005515=IPI, GO:0006805=IEA, GO:0005886=IDA, GO:0006626=IDA, GO:0051344=IEA, GO:0003713=TAS, GO:0003755=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0010738=IEA, GO:0022417=IDA, GO:0005829=TAS, GO:0044445=IEA, GO:0007165=TAS, GO:0005737=IDA, GO:0006457=IEA, GO:0051082=IDA, GO:0004871=TAS, GO:0036004=IDA, GO:0008134=TAS} negative regulation of cyclic-nucleotide phosphodiesterase activity, protein folding, protein maturation by protein folding, protein targeting to mitochondrion, regulation of protein kinase A signaling cascade, signal transduction, xenobiotic metabolic process cytoplasm, cytosol, cytosolic part, nucleolus, nucleus, plasma membrane GAF domain binding, peptidyl-prolyl cis-trans isomerase activity, protein binding, signal transducer activity, transcription coactivator activity, transcription factor binding, unfolded protein binding Human AIPL1 MGI UniProtKB {GO:0018343=PMID:14555765, GO:0001918=PMID:14555765, GO:0001917=GO_REF:0000019, GO:0005737=PMID:12374762, GO:0043066=GO_REF:0000019, GO:0007603=GO_REF:0000019, GO:0001895=GO_REF:0000019, GO:0006457=GO_REF:0000002, GO:0005634=PMID:12374762, GO:0051082=PMID:10615133, GO:0007601=GO_REF:0000037, GO:0030823=GO_REF:0000019} Q9NZN9 Aryl-hydrocarbon-interacting protein-like 1 protein 20101102 {GO:0018343=IDA, GO:0001918=IDA, GO:0001917=IEA, GO:0005737=IDA, GO:0043066=IEA, GO:0007603=IEA, GO:0001895=IEA, GO:0006457=IEA, GO:0005634=IDA, GO:0051082=TAS, GO:0007601=IEA, GO:0030823=IEA} negative regulation of apoptotic process, phototransduction, visible light, protein farnesylation, protein folding, regulation of cGMP metabolic process, retina homeostasis, visual perception cytoplasm, nucleus, photoreceptor inner segment farnesylated protein binding, unfolded protein binding Human AIRE HPA UniProtKB {GO:0005515=PMID:20085707, GO:0006355=PMID:18292755, GO:0005886=GO_REF:0000052, GO:0044212=PMID:18292755, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0015629=GO_REF:0000052, GO:0045182=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0042802=GO_REF:0000019, GO:0042393=PMID:18292755, GO:0005737=GO_REF:0000052, GO:0006955=PMID:9398840, GO:0045944=GO_REF:0000019, GO:0003682=PMID:18292755, GO:0006959=GO_REF:0000019, GO:0008270=PMID:19446523, GO:0045893=PMID:18292755} O43918 Autoimmune regulator protein 20110516 {GO:0005515=IPI, GO:0006355=IDA, GO:0005886=IDA, GO:0044212=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0015629=IDA, GO:0045182=IEA, GO:0006351=IEA, GO:0042802=IEA, GO:0042393=IDA, GO:0005737=IDA, GO:0006955=TAS, GO:0045944=IEA, GO:0003682=IDA, GO:0006959=IEA, GO:0008270=IDA, GO:0045893=IDA} humoral immune response, immune response, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent actin cytoskeleton, cytoplasm, nucleolus, nucleus, plasma membrane chromatin binding, histone binding, identical protein binding, protein binding, transcription regulatory region DNA binding, translation regulator activity, zinc ion binding Human AJAP1 UniProtKB UniProtKB {GO:0016323=GO_REF:0000039, GO:0016324=GO_REF:0000039, GO:0005912=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037} Q9UKB5 Adherens junction-associated protein 1 protein 20130413 {GO:0016323=IEA, GO:0016324=IEA, GO:0005912=IEA, GO:0016021=IEA, GO:0007155=IEA} cell adhesion adherens junction, apical plasma membrane, basolateral plasma membrane, integral to membrane Human UniProtKB-SubCell:SL-0015 AJUBA MGI UniProtKB {GO:0005515=PMID:18805794, GO:0035313=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0030032=GO_REF:0000019, GO:2000637=PMID:20616046, GO:0005634=PMID:18805794, GO:0005829=GO_REF:0000019, GO:0016339=GO_REF:0000019, GO:0031334=PMID:15870274, GO:0051015=GO_REF:0000019, GO:0000932=PMID:20616046, GO:0005911=PMID:12417594, GO:0043406=GO_REF:0000019, GO:0048041=GO_REF:0000019, GO:0043123=GO_REF:0000019, GO:0030334=GO_REF:0000019, GO:0033673=GO_REF:0000019, GO:0001666=PMID:22286099, GO:0005667=GO_REF:0000019, GO:0005815=GO_REF:0000039, GO:0045294=PMID:12417594, GO:0003714=PMID:18805794, GO:0000122=GO_REF:0000019, GO:0030027=GO_REF:0000019, GO:0043087=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0035331=PMID:20303269, GO:1900037=PMID:22286099, GO:0007049=GO_REF:0000037, GO:0035195=PMID:20616046, GO:0003682=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0034613=GO_REF:0000019, GO:0031328=GO_REF:0000019, GO:0005925=GO_REF:0000019, GO:0046474=GO_REF:0000019} Q96IF1 LIM domain-containing protein ajuba protein 20110107 {GO:0005515=IPI, GO:0035313=IEA, GO:0005886=IEA, GO:0030032=IEA, GO:2000637=IMP, GO:0005634=IDA, GO:0005829=IEA, GO:0016339=IEA, GO:0031334=IDA, GO:0051015=IEA, GO:0000932=IDA, GO:0005911=IDA, GO:0043406=IEA, GO:0048041=IEA, GO:0043123=IEA, GO:0030334=IEA, GO:0033673=IEA, GO:0001666=IDA, GO:0005667=IEA, GO:0005815=IEA, GO:0045294=IDA, GO:0003714=IDA, GO:0000122=IEA, GO:0030027=IEA, GO:0043087=IEA, GO:0006351=IEA, GO:0035331=IDA, GO:1900037=IDA, GO:0007049=IEA, GO:0035195=IMP, GO:0003682=IEA, GO:0008270=IEA, GO:0034613=IEA, GO:0031328=IEA, GO:0005925=IEA, GO:0046474=IEA} calcium-dependent cell-cell adhesion, cell cycle, cellular protein localization, focal adhesion assembly, gene silencing by miRNA, glycerophospholipid biosynthetic process, lamellipodium assembly, negative regulation of hippo signaling cascade, negative regulation of kinase activity, negative regulation of transcription from RNA polymerase II promoter, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of MAP kinase activity, positive regulation of cellular biosynthetic process, positive regulation of gene silencing by miRNA, positive regulation of protein complex assembly, regulation of GTPase activity, regulation of cell migration, regulation of cellular response to hypoxia, response to hypoxia, transcription, DNA-dependent, wound healing, spreading of epidermal cells cell-cell junction, cytoplasmic mRNA processing body, cytosol, focal adhesion, lamellipodium, microtubule organizing center, nucleus, plasma membrane, transcription factor complex actin filament binding, alpha-catenin binding, chromatin binding, protein binding, transcription corepressor activity, zinc ion binding Human AK1 HPA UniProtKB {GO:0046034=GO_REF:0000002, GO:0015949=Reactome:REACT_21330, GO:0005886=GO_REF:0000019, GO:0055086=Reactome:REACT_1698, GO:0036126=GO_REF:0000019, GO:0004017=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000002, GO:0001520=GO_REF:0000019, GO:0019205=GO_REF:0000002, GO:0005829=Reactome:REACT_763, GO:0006139=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0007050=GO_REF:0000019} Q5T9B7 Adenylate kinase isoenzyme 1 protein 20101115 {GO:0046034=IEA, GO:0015949=TAS, GO:0005886=IEA, GO:0055086=TAS, GO:0036126=IEA, GO:0004017=IEA, GO:0044281=TAS, GO:0005524=IEA, GO:0001520=IEA, GO:0019205=IEA, GO:0005829=TAS, GO:0006139=IEA, GO:0005737=IDA, GO:0007050=IEA} ATP metabolic process, cell cycle arrest, nucleobase-containing compound metabolic process, nucleobase-containing small molecule interconversion, nucleobase-containing small molecule metabolic process, small molecule metabolic process cytoplasm, cytosol, outer dense fiber, plasma membrane, sperm flagellum ATP binding, adenylate kinase activity, nucleobase-containing compound kinase activity Human AK2 Reactome UniProtKB {GO:0046033=GO_REF:0000019, GO:0015949=Reactome:REACT_21330, GO:0097066=GO_REF:0000019, GO:0046060=GO_REF:0000019, GO:0046034=GO_REF:0000019, GO:0097226=GO_REF:0000019, GO:0005743=GO_REF:0000019, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0004017=GO_REF:0000003, GO:0005524=GO_REF:0000037, GO:0005829=GO_REF:0000019, GO:0006119=GO_REF:0000019, GO:0019205=GO_REF:0000002, GO:0001889=GO_REF:0000019, GO:0005758=Reactome:REACT_2031, GO:0006139=GO_REF:0000002, GO:0007420=GO_REF:0000019, GO:0006172=GO_REF:0000019} P54819 Adenylate kinase 2, mitochondrial protein 20130301 {GO:0046033=IEA, GO:0015949=TAS, GO:0097066=IEA, GO:0046060=IEA, GO:0046034=IEA, GO:0097226=IEA, GO:0005743=IEA, GO:0055086=TAS, GO:0044281=TAS, GO:0004017=IEA, GO:0005524=IEA, GO:0005829=IEA, GO:0006119=IEA, GO:0019205=IEA, GO:0001889=IEA, GO:0005758=TAS, GO:0006139=IEA, GO:0007420=IEA, GO:0006172=IEA} ADP biosynthetic process, AMP metabolic process, ATP metabolic process, brain development, dATP metabolic process, liver development, nucleobase-containing compound metabolic process, nucleobase-containing small molecule interconversion, nucleobase-containing small molecule metabolic process, oxidative phosphorylation, response to thyroid hormone stimulus, small molecule metabolic process cytosol, mitochondrial inner membrane, mitochondrial intermembrane space, sperm mitochondrial sheath ATP binding, adenylate kinase activity, nucleobase-containing compound kinase activity Human AK3 BHF-UCL UniProtKB {GO:0005739=GO_REF:0000024, GO:0046041=PMID:11485571, GO:0046033=PMID:11485571, GO:0046051=PMID:11485571, GO:0007596=Reactome:REACT_604, GO:0005759=PMID:11485571, GO:0046039=PMID:11485571, GO:0004017=PMID:11485571, GO:0005525=GO_REF:0000037, GO:0046899=PMID:11485571, GO:0005524=GO_REF:0000002} Q9UIJ7 GTP:AMP phosphotransferase AK3, mitochondrial protein 20120528 {GO:0005739=ISS, GO:0046041=IDA, GO:0046033=IDA, GO:0046051=IDA, GO:0007596=TAS, GO:0005759=ISS, GO:0046039=IDA, GO:0004017=IDA, GO:0005525=IEA, GO:0046899=IDA, GO:0005524=IEA} AMP metabolic process, GTP metabolic process, ITP metabolic process, UTP metabolic process, blood coagulation mitochondrial matrix, mitochondrion ATP binding, GTP binding, adenylate kinase activity, nucleoside triphosphate adenylate kinase activity Human AK4 BHF-UCL UniProtKB {GO:0046033=PMID:19766732, GO:0046034=PMID:19766732, GO:0042493=GO_REF:0000019, GO:0043643=GO_REF:0000019, GO:0004017=PMID:19766732, GO:0005525=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0046899=PMID:19766732, GO:0005739=PMID:19766732, GO:0001889=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0005759=PMID:11485571, GO:0018885=GO_REF:0000019, GO:0046039=PMID:19766732} P27144 GTP:AMP phosphotransferase AK4, mitochondrial protein 20120528 {GO:0046033=IDA, GO:0046034=IDA, GO:0042493=IEA, GO:0043643=IEA, GO:0004017=IDA, GO:0005525=IEA, GO:0005524=IEA, GO:0046899=IDA, GO:0005739=IDA, GO:0001889=IEA, GO:0007420=IEA, GO:0005759=ISS, GO:0018885=IEA, GO:0046039=IDA} AMP metabolic process, ATP metabolic process, GTP metabolic process, brain development, carbon tetrachloride metabolic process, liver development, response to drug, tetracycline metabolic process mitochondrial matrix, mitochondrion ATP binding, GTP binding, adenylate kinase activity, nucleoside triphosphate adenylate kinase activity Human AK5 HPA UniProtKB {GO:0005813=GO_REF:0000052, GO:0046034=GO_REF:0000002, GO:0015949=Reactome:REACT_21330, GO:0008603=GO_REF:0000002, GO:0009220=PMID:10215863, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0004017=GO_REF:0000003, GO:0019206=Reactome:REACT_1716, GO:0005524=GO_REF:0000037, GO:0019205=GO_REF:0000002, GO:0005829=Reactome:REACT_1716, GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0006139=GO_REF:0000002, GO:0006172=PMID:10215863, GO:0006173=PMID:10215863} Q9Y6K8 Adenylate kinase isoenzyme 5 protein 20100326 {GO:0005813=IDA, GO:0046034=IEA, GO:0015949=TAS, GO:0008603=IEA, GO:0009220=TAS, GO:0055086=TAS, GO:0044281=TAS, GO:0004017=IEA, GO:0019206=EXP, GO:0005524=IEA, GO:0019205=IEA, GO:0005829=TAS, GO:0007165=IEA, GO:0005737=IDA, GO:0006139=IEA, GO:0006172=TAS, GO:0006173=TAS} ADP biosynthetic process, ATP metabolic process, dADP biosynthetic process, nucleobase-containing compound metabolic process, nucleobase-containing small molecule interconversion, nucleobase-containing small molecule metabolic process, pyrimidine ribonucleotide biosynthetic process, signal transduction, small molecule metabolic process centrosome, cytoplasm, cytosol ATP binding, adenylate kinase activity, cAMP-dependent protein kinase regulator activity, nucleobase-containing compound kinase activity, nucleoside kinase activity Human AK7 UniProtKB UniProtKB {GO:0002437=GO_REF:0000019, GO:0035083=GO_REF:0000019, GO:0003351=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0004127=PMID:21080915, GO:0007283=GO_REF:0000019, GO:0004017=PMID:21080915, GO:0005524=GO_REF:0000037, GO:0005829=GO_REF:0000039} Q96M32 Adenylate kinase 7 protein 20110120 {GO:0002437=IEA, GO:0035083=IEA, GO:0003351=IEA, GO:0007420=IEA, GO:0004127=IDA, GO:0007283=IEA, GO:0004017=IDA, GO:0005524=IEA, GO:0005829=IEA} brain development, cilium axoneme assembly, epithelial cilium movement, inflammatory response to antigenic stimulus, spermatogenesis cytosol ATP binding, adenylate kinase activity, cytidylate kinase activity Human AKAP1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0007596=Reactome:REACT_604, GO:0003723=GO_REF:0000037, GO:0005741=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0005829=Reactome:REACT_24992} Q92667 A-kinase anchor protein 1, mitochondrial protein 20101115 {GO:0005739=IDA, GO:0007596=TAS, GO:0003723=IEA, GO:0005741=IEA, GO:0016021=IEA, GO:0005829=TAS} blood coagulation cytosol, integral to membrane, mitochondrial outer membrane, mitochondrion RNA binding Human AKAP10 HPA UniProtKB {GO:0005739=GO_REF:0000039, GO:0007165=PMID:9326583, GO:0005737=GO_REF:0000052, GO:0008104=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0007596=Reactome:REACT_604, GO:0038032=GO_REF:0000002, GO:0005829=Reactome:REACT_24992} O43572 A-kinase anchor protein 10, mitochondrial protein 20101115 {GO:0005739=IEA, GO:0007165=TAS, GO:0005737=IDA, GO:0008104=IEA, GO:0005886=IDA, GO:0007596=TAS, GO:0038032=IEA, GO:0005829=TAS} blood coagulation, protein localization, signal transduction, termination of G-protein coupled receptor signaling pathway cytoplasm, cytosol, mitochondrion, plasma membrane Human AKAP11 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005815=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0008157=PMID:10209101, GO:0051018=PMID:10209101, GO:0007243=PMID:10209101} Q9UKA4 A-kinase anchor protein 11 protein 20111111 {GO:0005737=IDA, GO:0005886=IDA, GO:0005815=IEA, GO:0005730=IDA, GO:0008157=TAS, GO:0051018=TAS, GO:0007243=TAS} intracellular protein kinase cascade cytoplasm, microtubule organizing center, nucleolus, plasma membrane protein kinase A binding, protein phosphatase 1 binding Human AKAP12 HPA UniProtKB {GO:0005515=PMID:20029029, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0007186=PMID:10858453, GO:0008179=PMID:17081159, GO:0030819=PMID:17081159, GO:0006605=GO_REF:0000002, GO:0051018=PMID:10858453, GO:0005856=GO_REF:0000039, GO:0010739=PMID:17081159, GO:0005938=GO_REF:0000039} Q02952 A-kinase anchor protein 12 protein 20080205 {GO:0005515=IPI, GO:0005737=IDA, GO:0005886=IDA, GO:0007186=TAS, GO:0008179=IPI, GO:0030819=IMP, GO:0006605=IEA, GO:0051018=TAS, GO:0005856=IEA, GO:0010739=IMP, GO:0005938=IEA} G-protein coupled receptor signaling pathway, positive regulation of cAMP biosynthetic process, positive regulation of protein kinase A signaling cascade, protein targeting cell cortex, cytoplasm, cytoskeleton, plasma membrane adenylate cyclase binding, protein binding, protein kinase A binding Human AKAP13 HPA UniProtKB {GO:0005515=PMID:9627117, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0007264=Reactome:REACT_11044, GO:0035023=GO_REF:0000002, GO:0006915=Reactome:REACT_13638, GO:0005634=GO_REF:0000039, GO:0097190=Reactome:REACT_13720, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_19216, GO:0035556=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0016301=GO_REF:0000038, GO:1900169=GO_REF:0000019, GO:0004871=PMID:8290273, GO:0005089=GO_REF:0000002, GO:0004691=PMID:1618839} Q12802 A-kinase anchor protein 13 protein 20100326 {GO:0005515=IPI, GO:0051056=TAS, GO:0048011=TAS, GO:0007264=TAS, GO:0035023=IEA, GO:0006915=TAS, GO:0005634=IEA, GO:0097190=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0035556=IEA, GO:0005737=IDA, GO:0005543=IEA, GO:0016020=IEA, GO:0016301=IEA, GO:1900169=IEA, GO:0004871=TAS, GO:0005089=IEA, GO:0004691=NAS} apoptotic process, apoptotic signaling pathway, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, regulation of Rho protein signal transduction, regulation of glucocorticoid mediated signaling pathway, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytoplasm, cytosol, membrane, nucleus Rho guanyl-nucleotide exchange factor activity, cAMP-dependent protein kinase activity, kinase activity, metal ion binding, phospholipid binding, protein binding, signal transducer activity Human AKAP14 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0007283=GO_REF:0000019, GO:0051018=GO_REF:0000019} Q86UN6 A-kinase anchor protein 14 protein 20130413 {GO:0005737=IEA, GO:0007283=IEA, GO:0051018=IEA} spermatogenesis cytoplasm protein kinase A binding Human UniProtKB-SubCell:SL-0086 AKAP17A UniProtKB UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0007165=PMID:1438229, GO:0042113=PMID:1438229, GO:0006355=PMID:1438229, GO:0016607=PMID:16982639, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005634=PMID:19840947, GO:0043484=PMID:19840947, GO:0005681=GO_REF:0000037, GO:0051018=PMID:19840947} Q02040 A-kinase anchor protein 17A protein 20111206 {GO:0008380=IEA, GO:0006397=IEA, GO:0007165=NAS, GO:0042113=NAS, GO:0006355=NAS, GO:0016607=IDA, GO:0000166=IEA, GO:0003723=IEA, GO:0005634=IDA, GO:0043484=IMP, GO:0005681=IEA, GO:0051018=IDA} B cell activation, RNA splicing, mRNA processing, regulation of RNA splicing, regulation of transcription, DNA-dependent, signal transduction nuclear speck, nucleus, spliceosomal complex RNA binding, nucleotide binding, protein kinase A binding Human AKAP2 UniProtKB UniProtKB {GO:0019899=GO_REF:0000029} Q9Y2D5 A-kinase anchor protein 2 protein 20040301 {GO:0019899=NAS} enzyme binding Human AKAP3 BHF-UCL UniProtKB {GO:0005515=PMID:18421703, GO:0007338=PMID:10334916, GO:0008104=GO_REF:0000019, GO:0001669=GO_REF:0000039, GO:0007178=GO_REF:0000019, GO:0006928=GO_REF:0000019, GO:0007340=PMID:10319321, GO:0051018=GO_REF:0000019} O75969 A-kinase anchor protein 3 protein 20110221 {GO:0005515=IPI, GO:0007338=TAS, GO:0008104=IEA, GO:0001669=IEA, GO:0007178=IEA, GO:0006928=IEA, GO:0007340=TAS, GO:0051018=IEA} acrosome reaction, cellular component movement, protein localization, single fertilization, transmembrane receptor protein serine/threonine kinase signaling pathway acrosomal vesicle protein binding, protein kinase A binding Human UniProtKB:Q96C74 AKAP4 PINC UniProtKB {GO:0030018=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0005952=PMID:9822690, GO:0031514=PMID:9822690, GO:0006928=PMID:9822690, GO:0097228=GO_REF:0000019, GO:0030317=PMID:9822690, GO:0007338=PMID:9822690, GO:0007165=PMID:9822690, GO:0008104=GO_REF:0000019, GO:0030030=GO_REF:0000037, GO:0007178=GO_REF:0000019, GO:0051018=GO_REF:0000024, GO:0005856=PMID:9822690} Q5JQC9 A-kinase anchor protein 4 protein 20061106 {GO:0030018=IEA, GO:0048471=IEA, GO:0005952=NAS, GO:0031514=IDA, GO:0006928=TAS, GO:0097228=IEA, GO:0030317=IMP, GO:0007338=TAS, GO:0007165=TAS, GO:0008104=IEA, GO:0030030=IEA, GO:0007178=IEA, GO:0051018=ISS, GO:0005856=TAS} cell projection organization, cellular component movement, protein localization, signal transduction, single fertilization, sperm motility, transmembrane receptor protein serine/threonine kinase signaling pathway Z disc, cAMP-dependent protein kinase complex, cytoskeleton, motile cilium, perinuclear region of cytoplasm, sperm principal piece protein kinase A binding Human AKAP5 IntAct UniProtKB {GO:0005515=PMID:11287423, GO:0005516=GO_REF:0000037, GO:0005886=Reactome:REACT_18393, GO:0008179=PMID:17081159, GO:0030819=PMID:17081159, GO:0007268=Reactome:REACT_13685, GO:0006605=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0010739=PMID:17081159, GO:0005829=Reactome:REACT_18393, GO:0007165=GO_REF:0000002, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0051018=PMID:1512224} P24588 A-kinase anchor protein 5 protein 20130415 {GO:0005515=IPI, GO:0005516=IEA, GO:0005886=TAS, GO:0008179=IPI, GO:0030819=IMP, GO:0007268=TAS, GO:0006605=IEA, GO:0044281=TAS, GO:0010739=IMP, GO:0005829=TAS, GO:0007165=IEA, GO:0006112=TAS, GO:0050796=TAS, GO:0051018=TAS} energy reserve metabolic process, positive regulation of cAMP biosynthetic process, positive regulation of protein kinase A signaling cascade, protein targeting, regulation of insulin secretion, signal transduction, small molecule metabolic process, synaptic transmission cytosol, plasma membrane adenylate cyclase binding, calmodulin binding, protein binding, protein kinase A binding Human UniProtKB:P35561 AKAP6 BHF-UCL UniProtKB {GO:0005515=PMID:17923693, GO:0031965=GO_REF:0000039, GO:0016529=PMID:10830164, GO:0005102=PMID:10830164, GO:0034704=PMID:10830164, GO:0006605=PMID:10413680, GO:0005635=PMID:10413680, GO:0051018=PMID:10830164} Q13023 A-kinase anchor protein 6 protein 20090226 {GO:0005515=IPI, GO:0031965=IEA, GO:0016529=IDA, GO:0005102=IPI, GO:0034704=IDA, GO:0006605=NAS, GO:0005635=IDA, GO:0051018=TAS} protein targeting calcium channel complex, nuclear envelope, nuclear membrane, sarcoplasmic reticulum protein binding, protein kinase A binding, receptor binding Human UniProtKB:Q92736 AKAP7 UniProtKB UniProtKB {GO:0005515=PMID:17244820, GO:0034237=GO_REF:0000019, GO:0005886=PMID:10613906, GO:0010738=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0003824=GO_REF:0000002, GO:0005829=PMID:10613906, GO:0005622=GO_REF:0000002, GO:0035556=PMID:10613906, GO:0016324=GO_REF:0000019, GO:0008104=PMID:9545239, GO:0051018=PMID:10613906, GO:0006811=PMID:9545239, GO:0019901=GO_REF:0000019, GO:0016208=GO_REF:0000019, GO:0016070=GO_REF:0000002, GO:0019904=GO_REF:0000019, GO:0030315=GO_REF:0000019, GO:0008022=GO_REF:0000019, GO:0016328=PMID:10613906, GO:0043234=GO_REF:0000019, GO:0008150=GO_REF:0000015, GO:0032947=GO_REF:0000019, GO:0016529=GO_REF:0000019, GO:0070382=GO_REF:0000019} Q9P0M2 A-kinase anchor protein 7 isoform gamma protein 20120817 {GO:0005515=IPI, GO:0034237=IEA, GO:0005886=TAS, GO:0010738=IEA, GO:0005634=IEA, GO:0003824=IEA, GO:0005829=IDA, GO:0005622=IEA, GO:0035556=TAS, GO:0016324=IEA, GO:0008104=IC, GO:0051018=IDA, GO:0006811=TAS, GO:0019901=IEA, GO:0016208=IEA, GO:0016070=IEA, GO:0019904=IEA, GO:0030315=IEA, GO:0008022=IEA, GO:0016328=IDA, GO:0043234=IEA, GO:0008150=ND, GO:0032947=IEA, GO:0016529=IEA, GO:0070382=IEA} RNA metabolic process, biological_process, intracellular signal transduction, ion transport, protein localization, regulation of protein kinase A signaling cascade T-tubule, apical plasma membrane, cytosol, exocytic vesicle, intracellular, lateral plasma membrane, nucleus, plasma membrane, protein complex, sarcoplasmic reticulum AMP binding, catalytic activity, protein C-terminus binding, protein binding, protein complex scaffold, protein domain specific binding, protein kinase A binding, protein kinase A regulatory subunit binding, protein kinase binding Human UniProtKB:P17252 AKAP8 HPA UniProtKB {GO:0000793=GO_REF:0000019, GO:0007076=GO_REF:0000019, GO:0034237=GO_REF:0000019, GO:0005794=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000002, GO:0016363=GO_REF:0000024, GO:0005739=GO_REF:0000019, GO:0007165=PMID:9473338, GO:0007067=PMID:9473338, GO:0001939=GO_REF:0000019, GO:0003690=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0006810=GO_REF:0000002, GO:0008270=GO_REF:0000019} O43823 A-kinase anchor protein 8 protein 20080818 {GO:0000793=IEA, GO:0007076=IEA, GO:0034237=IEA, GO:0005794=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0016363=ISS, GO:0005739=IEA, GO:0007165=TAS, GO:0007067=TAS, GO:0001939=IEA, GO:0003690=IEA, GO:0016020=IEA, GO:0006810=IEA, GO:0008270=IEA} mitosis, mitotic chromosome condensation, signal transduction, transport Golgi apparatus, condensed chromosome, female pronucleus, membrane, mitochondrion, nuclear matrix, nucleolus, nucleus DNA binding, double-stranded DNA binding, protein kinase A regulatory subunit binding, zinc ion binding NOT Human AKAP8L IntAct UniProtKB {GO:0005515=PMID:18313049, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000039, GO:0017151=PMID:10748171, GO:0005634=PMID:10761695, GO:0003677=GO_REF:0000002, GO:0016363=PMID:16391387, GO:0046872=GO_REF:0000037} Q9ULX6 A-kinase anchor protein 8-like protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0005737=IEA, GO:0017151=TAS, GO:0005634=TAS, GO:0003677=IEA, GO:0016363=IDA, GO:0046872=IEA} biological_process cytoplasm, nuclear matrix, nucleus DEAD/H-box RNA helicase binding, DNA binding, metal ion binding, protein binding Human UniProtKB:Q68DV7 AKAP9 HPA UniProtKB {GO:0005515=PMID:12163479, GO:0005813=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0005102=PMID:9482789, GO:0007268=PMID:9482789, GO:0043231=GO_REF:0000052, GO:0005829=Reactome:REACT_15470, GO:0007165=PMID:10390370, GO:0016301=GO_REF:0000038, GO:0000086=Reactome:REACT_2203, GO:0006810=PMID:10390370, GO:0005856=PMID:9482789, GO:0000278=Reactome:REACT_152, GO:0000242=GO_REF:0000019} Q99996 A-kinase anchor protein 9 protein 20120912 {GO:0005515=IPI, GO:0005813=IDA, GO:0005794=IDA, GO:0005102=TAS, GO:0007268=TAS, GO:0043231=IDA, GO:0005829=TAS, GO:0007165=TAS, GO:0016301=IEA, GO:0000086=TAS, GO:0006810=TAS, GO:0005856=TAS, GO:0000278=TAS, GO:0000242=IEA} G2/M transition of mitotic cell cycle, mitotic cell cycle, signal transduction, synaptic transmission, transport Golgi apparatus, centrosome, cytoskeleton, cytosol, intracellular membrane-bounded organelle, pericentriolar material kinase activity, protein binding, receptor binding Human AKD1 InterPro UniProtKB {GO:0017111=GO_REF:0000002, GO:0006139=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0019205=GO_REF:0000002} Q5TCS8 Adenylate kinase domain-containing protein 1 protein 20130413 {GO:0017111=IEA, GO:0006139=IEA, GO:0005524=IEA, GO:0019205=IEA} nucleobase-containing compound metabolic process ATP binding, nucleobase-containing compound kinase activity, nucleoside-triphosphatase activity Human InterPro:IPR000850 AKIP1 IntAct UniProtKB {GO:0005515=PMID:15630084, GO:0034446=GO_REF:0000019, GO:0005634=GO_REF:0000039} Q9NQ31 A-kinase-interacting protein 1 protein 20130415 {GO:0005515=IPI, GO:0034446=IEA, GO:0005634=IEA} substrate adhesion-dependent cell spreading nucleus protein binding Human UniProtKB:P17612 AKIRIN1 HPA UniProtKB {GO:0031965=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0043231=GO_REF:0000052} Q9H9L7 Akirin-1 protein 20120912 {GO:0031965=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0043231=IDA} intracellular membrane-bounded organelle, nuclear membrane, nucleolus, nucleus Human AKIRIN2 UniProtKB UniProtKB {GO:0032755=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0017053=GO_REF:0000024, GO:0045944=GO_REF:0000019, GO:0045087=GO_REF:0000037, GO:0010950=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0005634=PMID:18066067, GO:0009790=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q53H80 Akirin-2 protein 20080923 {GO:0032755=IEA, GO:0008284=IEA, GO:0017053=ISS, GO:0045944=IEA, GO:0045087=IEA, GO:0010950=IEA, GO:0032496=IEA, GO:0005634=IDA, GO:0009790=IEA, GO:0000122=IEA, GO:0006351=IEA} embryo development, innate immune response, negative regulation of transcription from RNA polymerase II promoter, positive regulation of cell proliferation, positive regulation of endopeptidase activity, positive regulation of interleukin-6 production, positive regulation of transcription from RNA polymerase II promoter, response to lipopolysaccharide, transcription, DNA-dependent nucleus, transcriptional repressor complex Human AKNA UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q7Z591 AT-hook-containing transcription factor protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding Human UniProtKB-SubCell:SL-0191 AKNAD1 HPA UniProtKB {GO:0005737=GO_REF:0000052} Q5T1N2 Protein AKNAD1 protein 20101115 {GO:0005737=IDA} cytoplasm Human AKR1A1 ENSEMBL UniProtKB {GO:0004032=PMID:2498333, GO:0016324=GO_REF:0000019, GO:0046185=GO_REF:0000019, GO:0019853=GO_REF:0000019, GO:0006081=PMID:2498333, GO:0042840=GO_REF:0000019, GO:0006006=PMID:2498333, GO:0009055=PMID:2498333, GO:0047939=GO_REF:0000019, GO:0005829=GO_REF:0000019} Q5T621 "Alcohol dehydrogenase ""NADP(+)""" protein 20130413 {GO:0004032=TAS, GO:0016324=IEA, GO:0046185=IEA, GO:0019853=IEA, GO:0006081=TAS, GO:0042840=IEA, GO:0006006=TAS, GO:0009055=TAS, GO:0047939=IEA, GO:0005829=IEA} D-glucuronate catabolic process, L-ascorbic acid biosynthetic process, aldehyde catabolic process, cellular aldehyde metabolic process, glucose metabolic process apical plasma membrane, cytosol L-glucuronate reductase activity, alditol:NADP+ 1-oxidoreductase activity, electron carrier activity Human Ensembl:ENSMUSP00000030455 AKR1B1 HPA UniProtKB {GO:0044598=PMID:20837989, GO:0044597=PMID:20837989, GO:0005975=PMID:2112546, GO:0043795=PMID:20837989, GO:0005730=GO_REF:0000052, GO:0006950=PMID:8435445, GO:0009055=PMID:2112546, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0005615=PMID:2112546, GO:0005829=Reactome:REACT_9986, GO:0004032=GO_REF:0000003, GO:0005737=GO_REF:0000052, GO:0004033=PMID:8435445, GO:0006700=Reactome:REACT_11038, GO:0016491=GO_REF:0000002, GO:0008202=Reactome:REACT_11057} P15121 Aldose reductase protein 20100326 {GO:0044598=IMP, GO:0044597=IMP, GO:0005975=TAS, GO:0043795=IDA, GO:0005730=IDA, GO:0006950=TAS, GO:0009055=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0005615=TAS, GO:0005829=TAS, GO:0004032=IEA, GO:0005737=IDA, GO:0004033=TAS, GO:0006700=TAS, GO:0016491=IEA, GO:0008202=TAS} C21-steroid hormone biosynthetic process, carbohydrate metabolic process, daunorubicin metabolic process, doxorubicin metabolic process, response to stress, small molecule metabolic process, steroid metabolic process cytoplasm, cytosol, extracellular space, nucleolus, nucleus alditol:NADP+ 1-oxidoreductase activity, aldo-keto reductase (NADP) activity, electron carrier activity, glyceraldehyde oxidoreductase activity, oxidoreductase activity Human AKR1B10 Reactome UniProtKB {GO:0044598=PMID:20837989, GO:0047718=PMID:20837989, GO:0045550=PMID:21187079, GO:0044597=PMID:20837989, GO:0007603=Reactome:REACT_160125, GO:0001758=PMID:21851338, GO:0007586=PMID:9565553, GO:0006081=PMID:9565553, GO:0005576=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0001523=Reactome:REACT_24968, GO:0005764=GO_REF:0000039, GO:0005829=Reactome:REACT_160311, GO:0004033=PMID:9565553, GO:0016488=PMID:21187079, GO:0008202=PMID:9565553} O60218 Aldo-keto reductase family 1 member B10 protein 20130301 {GO:0044598=IMP, GO:0047718=IDA, GO:0045550=IDA, GO:0044597=IMP, GO:0007603=TAS, GO:0001758=IDA, GO:0007586=TAS, GO:0006081=TAS, GO:0005576=IEA, GO:0005575=ND, GO:0001523=TAS, GO:0005764=IEA, GO:0005829=TAS, GO:0004033=TAS, GO:0016488=IDA, GO:0008202=TAS} cellular aldehyde metabolic process, daunorubicin metabolic process, digestion, doxorubicin metabolic process, farnesol catabolic process, phototransduction, visible light, retinoid metabolic process, steroid metabolic process cellular_component, cytosol, extracellular region, lysosome aldo-keto reductase (NADP) activity, geranylgeranyl reductase activity, indanol dehydrogenase activity, retinal dehydrogenase activity Human AKR1C1 Reactome UniProtKB {GO:0044598=PMID:20837989, GO:0031406=PMID:8486699, GO:0046683=PMID:16079077, GO:0032052=PMID:8486699, GO:0006805=PMID:8486699, GO:0044597=PMID:20837989, GO:0007603=Reactome:REACT_160125, GO:0047086=PMID:21232532, GO:0005829=Reactome:REACT_160311, GO:0030299=PMID:8486699, GO:0016655=PMID:20837989, GO:0042574=PMID:21851338, GO:0071395=PMID:19487289, GO:0047115=PMID:8486699, GO:0008206=PMID:8486699, GO:0051260=PMID:8486699, GO:0047042=PMID:8486699, GO:0042632=PMID:8486699, GO:0047718=GO_REF:0000003, GO:0007586=PMID:8486699, GO:0047006=GO_REF:0000003, GO:0001523=Reactome:REACT_24968, GO:0004032=PMID:21232532, GO:0004033=PMID:7789999, GO:0015721=PMID:8486699, GO:0042448=PMID:21232532, GO:0016491=GO_REF:0000002, GO:0018636=PMID:21851338, GO:0055114=PMID:21232532} Q04828 Aldo-keto reductase family 1 member C1 protein 20130301 {GO:0044598=IMP, GO:0031406=IDA, GO:0046683=IEP, GO:0032052=IDA, GO:0006805=NAS, GO:0044597=IMP, GO:0007603=TAS, GO:0047086=IDA, GO:0005829=TAS, GO:0030299=TAS, GO:0016655=IDA, GO:0042574=IDA, GO:0071395=IDA, GO:0047115=IDA, GO:0008206=IDA, GO:0051260=IDA, GO:0047042=IDA, GO:0042632=TAS, GO:0047718=IEA, GO:0007586=IDA, GO:0047006=IEA, GO:0001523=TAS, GO:0004032=IDA, GO:0004033=TAS, GO:0015721=TAS, GO:0042448=IDA, GO:0016491=IEA, GO:0018636=IDA, GO:0055114=IDA} bile acid and bile salt transport, bile acid metabolic process, cellular response to jasmonic acid stimulus, cholesterol homeostasis, daunorubicin metabolic process, digestion, doxorubicin metabolic process, intestinal cholesterol absorption, oxidation-reduction process, phototransduction, visible light, progesterone metabolic process, protein homooligomerization, response to organophosphorus, retinal metabolic process, retinoid metabolic process, xenobiotic metabolic process cytosol 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity, alditol:NADP+ 1-oxidoreductase activity, aldo-keto reductase (NADP) activity, androsterone dehydrogenase (B-specific) activity, bile acid binding, carboxylic acid binding, indanol dehydrogenase activity, ketosteroid monooxygenase activity, oxidoreductase activity, oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor, phenanthrene 9,10-monooxygenase activity, trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity Human AKR1C2 UniProtKB UniProtKB {GO:0044598=PMID:20837989, GO:0031406=PMID:8573067, GO:0032052=PMID:8573067, GO:0006693=PMID:8573067, GO:0044597=PMID:20837989, GO:0047086=PMID:21232532, GO:0007586=PMID:8573067, GO:0004032=PMID:21232532, GO:0005737=GO_REF:0000039, GO:0016655=PMID:20837989, GO:0007186=PMID:18508192, GO:0071395=PMID:19487289, GO:0047026=GO_REF:0000003, GO:0047115=PMID:8573067, GO:0042448=PMID:21232532, GO:0016491=GO_REF:0000002, GO:0018636=PMID:21851338, GO:0008202=PMID:8573067, GO:0055114=PMID:21232532} P52895 Aldo-keto reductase family 1 member C2 protein 20120508 {GO:0044598=IMP, GO:0031406=IDA, GO:0032052=IDA, GO:0006693=IDA, GO:0044597=IMP, GO:0047086=IDA, GO:0007586=IDA, GO:0004032=IDA, GO:0005737=IEA, GO:0016655=IDA, GO:0007186=IDA, GO:0071395=IDA, GO:0047026=IEA, GO:0047115=IDA, GO:0042448=IDA, GO:0016491=IEA, GO:0018636=IDA, GO:0008202=IDA, GO:0055114=IDA} G-protein coupled receptor signaling pathway, cellular response to jasmonic acid stimulus, daunorubicin metabolic process, digestion, doxorubicin metabolic process, oxidation-reduction process, progesterone metabolic process, prostaglandin metabolic process, steroid metabolic process cytoplasm alditol:NADP+ 1-oxidoreductase activity, androsterone dehydrogenase (A-specific) activity, bile acid binding, carboxylic acid binding, ketosteroid monooxygenase activity, oxidoreductase activity, oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor, phenanthrene 9,10-monooxygenase activity, trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity Human AKR1C3 LIFEdb UniProtKB {GO:0044598=PMID:20837989, GO:0019369=Reactome:REACT_147851, GO:0044597=PMID:20837989, GO:0006693=PMID:20036328, GO:0001758=PMID:21851338, GO:0007603=Reactome:REACT_160125, GO:0047017=GO_REF:0000003, GO:0005622=GO_REF:0000054, GO:0016488=PMID:21187079, GO:0047020=PMID:22170488, GO:0047026=GO_REF:0000003, GO:0071395=PMID:19487289, GO:0047023=PMID:16983398, GO:0047115=GO_REF:0000003, GO:0044259=PMID:18641923, GO:0004745=PMID:21851338, GO:0010942=PMID:21787718, GO:0045550=PMID:21187079, GO:1900053=PMID:21851338, GO:0061370=PMID:16983398, GO:0004032=PMID:21232532, GO:0004033=PMID:9792917, GO:0048385=PMID:21851338, GO:0007186=PMID:18508192, GO:0042448=PMID:21232532, GO:0016491=GO_REF:0000002, GO:2000379=PMID:19442656, GO:0055114=PMID:19442656, GO:0008284=PMID:21851338, GO:0047086=PMID:21232532, GO:0044281=Reactome:REACT_111217, GO:0070293=PMID:16157291, GO:0005829=Reactome:REACT_160311, GO:0016655=PMID:20837989, GO:0042574=PMID:21851338, GO:0071277=PMID:22170488, GO:0047787=PMID:16983398, GO:0047045=GO_REF:0000003, GO:0071276=PMID:21787718, GO:0071379=PMID:22170488, GO:0008202=PMID:20036328, GO:0019371=Reactome:REACT_150149, GO:0047718=GO_REF:0000003, GO:0001523=Reactome:REACT_24968, GO:0036131=GO_REF:0000003, GO:0035410=PMID:16983398, GO:0047035=GO_REF:0000003, GO:0034614=PMID:21787718, GO:0018636=PMID:21851338, GO:2000353=PMID:19442656, GO:0008584=PMID:19942269} P42330 Aldo-keto reductase family 1 member C3 protein 20100607 {GO:0044598=IMP, GO:0019369=TAS, GO:0044597=IMP, GO:0006693=IEP, GO:0001758=IDA, GO:0007603=TAS, GO:0047017=IEA, GO:0005622=IDA, GO:0016488=IDA, GO:0047020=IDA, GO:0047026=IEA, GO:0071395=IDA, GO:0047023=IDA, GO:0047115=IEA, GO:0044259=IEP, GO:0004745=IDA, GO:0010942=IDA, GO:0045550=IDA, GO:1900053=IDA, GO:0061370=IMP, GO:0004032=IDA, GO:0004033=TAS, GO:0048385=IDA, GO:0007186=IDA, GO:0042448=IDA, GO:0016491=IEA, GO:2000379=IDA, GO:0055114=IDA, GO:0008284=IMP, GO:0047086=IDA, GO:0044281=TAS, GO:0070293=NAS, GO:0005829=TAS, GO:0016655=IDA, GO:0042574=IDA, GO:0071277=IDA, GO:0047787=IDA, GO:0047045=IEA, GO:0071276=IDA, GO:0071379=IDA, GO:0008202=IEP, GO:0019371=TAS, GO:0047718=IEA, GO:0001523=TAS, GO:0036131=IEA, GO:0035410=IDA, GO:0047035=IEA, GO:0034614=IDA, GO:0018636=IDA, GO:2000353=IDA, GO:0008584=IEP} G-protein coupled receptor signaling pathway, arachidonic acid metabolic process, cellular response to cadmium ion, cellular response to calcium ion, cellular response to jasmonic acid stimulus, cellular response to prostaglandin stimulus, cellular response to reactive oxygen species, cyclooxygenase pathway, daunorubicin metabolic process, doxorubicin metabolic process, farnesol catabolic process, male gonad development, multicellular organismal macromolecule metabolic process, negative regulation of retinoic acid biosynthetic process, oxidation-reduction process, phototransduction, visible light, positive regulation of cell death, positive regulation of cell proliferation, positive regulation of endothelial cell apoptotic process, positive regulation of reactive oxygen species metabolic process, progesterone metabolic process, prostaglandin metabolic process, regulation of retinoic acid receptor signaling pathway, renal absorption, retinal metabolic process, retinoid metabolic process, small molecule metabolic process, steroid metabolic process, testosterone biosynthetic process cytosol, intracellular 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity, alditol:NADP+ 1-oxidoreductase activity, aldo-keto reductase (NADP) activity, androsterone dehydrogenase (A-specific) activity, androsterone dehydrogenase activity, delta4-3-oxosteroid 5beta-reductase activity, dihydrotestosterone 17-beta-dehydrogenase activity, geranylgeranyl reductase activity, indanol dehydrogenase activity, ketosteroid monooxygenase activity, oxidoreductase activity, oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor, phenanthrene 9,10-monooxygenase activity, prostaglandin D2 11-ketoreductase activity, prostaglandin-F synthase activity, retinal dehydrogenase activity, retinol dehydrogenase activity, testosterone 17-beta-dehydrogenase (NADP+) activity, testosterone dehydrogenase (NAD+) activity, trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity Human AKR1C4 Reactome UniProtKB {GO:0044598=PMID:20837989, GO:0044597=PMID:20837989, GO:0007603=Reactome:REACT_160125, GO:0001758=PMID:21851338, GO:0006699=Reactome:REACT_11054, GO:0008209=PMID:7650035, GO:0009055=PMID:8172617, GO:0044281=Reactome:REACT_111217, GO:0015125=PMID:8172617, GO:0001523=Reactome:REACT_24968, GO:0005829=Reactome:REACT_160311, GO:0047743=GO_REF:0000003, GO:0005737=PMID:2187532, GO:0004033=PMID:7650035, GO:0016655=PMID:20837989, GO:0071395=PMID:19487289, GO:0015721=PMID:8172617, GO:0047023=PMID:21851338, GO:0008206=Reactome:REACT_11040, GO:0047042=GO_REF:0000003, GO:0008202=PMID:8274401} P17516 Aldo-keto reductase family 1 member C4 protein 20130301 {GO:0044598=IMP, GO:0044597=IMP, GO:0007603=TAS, GO:0001758=IDA, GO:0006699=TAS, GO:0008209=TAS, GO:0009055=TAS, GO:0044281=TAS, GO:0015125=TAS, GO:0001523=TAS, GO:0005829=TAS, GO:0047743=IEA, GO:0005737=TAS, GO:0004033=TAS, GO:0016655=IDA, GO:0071395=IDA, GO:0015721=TAS, GO:0047023=IDA, GO:0008206=TAS, GO:0047042=IEA, GO:0008202=TAS} androgen metabolic process, bile acid and bile salt transport, bile acid biosynthetic process, bile acid metabolic process, cellular response to jasmonic acid stimulus, daunorubicin metabolic process, doxorubicin metabolic process, phototransduction, visible light, retinoid metabolic process, small molecule metabolic process, steroid metabolic process cytoplasm, cytosol aldo-keto reductase (NADP) activity, androsterone dehydrogenase (B-specific) activity, androsterone dehydrogenase activity, bile acid transmembrane transporter activity, chlordecone reductase activity, electron carrier activity, oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor, retinal dehydrogenase activity Human AKR1D1 Reactome UniProtKB {GO:0006707=PMID:7508385, GO:0006699=Reactome:REACT_11054, GO:0008209=PMID:7508385, GO:0030573=GO_REF:0000037, GO:0007586=PMID:7508385, GO:0047787=GO_REF:0000003, GO:0008206=Reactome:REACT_11040, GO:0044281=Reactome:REACT_111217, GO:0008207=PMID:7508385, GO:0005496=PMID:7508385, GO:0005829=Reactome:REACT_10131, GO:0055114=PMID:7508385} P51857 3-oxo-5-beta-steroid 4-dehydrogenase protein 20130301 {GO:0006707=IDA, GO:0006699=TAS, GO:0008209=IDA, GO:0030573=IEA, GO:0007586=IDA, GO:0047787=IEA, GO:0008206=TAS, GO:0044281=TAS, GO:0008207=IDA, GO:0005496=TAS, GO:0005829=TAS, GO:0055114=IDA} C21-steroid hormone metabolic process, androgen metabolic process, bile acid biosynthetic process, bile acid catabolic process, bile acid metabolic process, cholesterol catabolic process, digestion, oxidation-reduction process, small molecule metabolic process cytosol delta4-3-oxosteroid 5beta-reductase activity, steroid binding Human AKR7A2 PINC UniProtKB {GO:0044598=PMID:20837989, GO:0019119=PMID:20837989, GO:0005739=GO_REF:0000019, GO:0004032=GO_REF:0000019, GO:0044597=PMID:20837989, GO:0005794=GO_REF:0000039, GO:0005975=PMID:9576847, GO:0006081=PMID:9576847, GO:0009055=PMID:9576847} O43488 Aflatoxin B1 aldehyde reductase member 2 protein 20030904 {GO:0044598=IMP, GO:0019119=IDA, GO:0005739=IEA, GO:0004032=IEA, GO:0044597=IMP, GO:0005794=IEA, GO:0005975=TAS, GO:0006081=TAS, GO:0009055=TAS} carbohydrate metabolic process, cellular aldehyde metabolic process, daunorubicin metabolic process, doxorubicin metabolic process Golgi apparatus, mitochondrion alditol:NADP+ 1-oxidoreductase activity, electron carrier activity, phenanthrene-9,10-epoxide hydrolase activity Human AKR7A3 PINC UniProtKB {GO:0004032=GO_REF:0000019, GO:0004033=PMID:10383892, GO:0006081=PMID:10383892, GO:0009055=PMID:10383892, GO:0046223=GO_REF:0000019, GO:0005829=PMID:10383892} O95154 Aflatoxin B1 aldehyde reductase member 3 protein 20030904 {GO:0004032=IEA, GO:0004033=TAS, GO:0006081=TAS, GO:0009055=TAS, GO:0046223=IEA, GO:0005829=TAS} aflatoxin catabolic process, cellular aldehyde metabolic process cytosol alditol:NADP+ 1-oxidoreductase activity, aldo-keto reductase (NADP) activity, electron carrier activity Human AKR7L UniProtKB UniProtKB {GO:0016491=GO_REF:0000037} Q8NHP1 Aflatoxin B1 aldehyde reductase member 4 protein 20130413 {GO:0016491=IEA} oxidoreductase activity Human UniProtKB-KW:KW-0560 AKT1 BHF-UCL UniProtKB {GO:0005515=PMID:19162005, GO:0042640=GO_REF:0000019, GO:0030307=PMID:19203586, GO:0007281=GO_REF:0000019, GO:0030154=PMID:21432781, GO:0046889=PMID:8940145, GO:0030163=GO_REF:0000019, GO:0046329=GO_REF:0000019, GO:0046777=PMID:16280327, GO:1901976=PMID:21432781, GO:1900740=Reactome:REACT_697, GO:0008637=GO_REF:0000019, GO:0060644=PMID:21432781, GO:0015758=GO_REF:0000019, GO:0018105=PMID:16139227, GO:0046326=PMID:8940145, GO:0005080=GO_REF:0000019, GO:0060716=GO_REF:0000019, GO:0000060=PMID:16280327, GO:0005979=PMID:8940145, GO:0032869=GO_REF:0000024, GO:0005978=GO_REF:0000019, GO:0005819=GO_REF:0000019, GO:0001893=GO_REF:0000019, GO:0010748=PMID:16814735, GO:0030168=Reactome:REACT_798, GO:0070141=PMID:18483258, GO:0032270=GO_REF:0000024, GO:0051000=PMID:10376603, GO:0045087=Reactome:REACT_6802, GO:0051146=GO_REF:0000019, GO:0016044=Reactome:REACT_11123, GO:0016567=GO_REF:0000019, GO:0050999=Reactome:REACT_12477, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0032094=GO_REF:0000019, GO:0005829=Reactome:REACT_160114, GO:0032880=GO_REF:0000019, GO:0051091=PMID:19057511, GO:0033138=PMID:19667065, GO:0006954=GO_REF:0000019, GO:0045907=GO_REF:0000019, GO:0006006=GO_REF:0000019, GO:0046209=Reactome:REACT_12508, GO:0030235=PMID:10376603, GO:0043154=GO_REF:0000024, GO:0048011=Reactome:REACT_11061, GO:0045725=PMID:17925406, GO:0043325=PMID:19203586, GO:0048015=Reactome:REACT_12464, GO:0071456=GO_REF:0000019, GO:0042593=GO_REF:0000019, GO:0032287=GO_REF:0000019, GO:0006417=GO_REF:0000037, GO:0045861=PMID:18387192, GO:0004672=PMID:10570282, GO:0071364=GO_REF:0000019, GO:0004674=PMID:19667065, GO:0007596=Reactome:REACT_604, GO:0048009=PMID:8978681, GO:0010467=Reactome:REACT_71, GO:0009408=PMID:10958679, GO:0034405=PMID:10376603, GO:0006412=GO_REF:0000019, GO:0010907=PMID:16814735, GO:0006809=PMID:10376602, GO:0042802=PMID:16280327, GO:0007173=Reactome:REACT_9417, GO:0010765=GO_REF:0000019, GO:0016301=PMID:14749367, GO:0030334=PMID:21432781, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0007568=GO_REF:0000019, GO:0005547=PMID:19203586, GO:0030027=GO_REF:0000019, GO:0001649=GO_REF:0000019, GO:0043536=PMID:20011604, GO:0016310=PMID:20333297, GO:0045792=GO_REF:0000019, GO:0007186=PMID:10570282, GO:0008543=Reactome:REACT_9470, GO:0010975=GO_REF:0000024, GO:0030030=GO_REF:0000019, GO:0010507=PMID:18387192, GO:0045600=PMID:8940145, GO:0043491=GO_REF:0000019, GO:0005654=Reactome:REACT_147870, GO:0019899=GO_REF:0000024, GO:0008286=PMID:8978681, GO:0005886=Reactome:REACT_147896, GO:0031999=PMID:16814735, GO:0008283=PMID:21432781, GO:0031295=Reactome:REACT_19344, GO:0032436=GO_REF:0000019, GO:0006924=PMID:14749367, GO:0045429=PMID:10376603, GO:0035556=PMID:14749367, GO:0005737=GO_REF:0000024, GO:0005543=GO_REF:0000002, GO:0090201=GO_REF:0000024, GO:0045944=GO_REF:0000019, GO:0015630=GO_REF:0000052, GO:0060709=GO_REF:0000019, GO:0043066=PMID:16604263, GO:0043065=GO_REF:0000019, GO:0006915=Reactome:REACT_578, GO:0005524=PMID:16540465, GO:0097193=Reactome:REACT_964, GO:0010951=PMID:18387192, GO:0007165=PMID:21432781, GO:0031659=PMID:18483258, GO:0031018=Reactome:REACT_13819, GO:0001934=PMID:19057511, GO:0006468=PMID:14749367, GO:0006469=GO_REF:0000024, GO:0006464=PMID:10570282, GO:0090004=PMID:8940145} P31749 RAC-alpha serine/threonine-protein kinase protein 20110127 {GO:0005515=IPI, GO:0042640=IEA, GO:0030307=IDA, GO:0007281=IEA, GO:0030154=TAS, GO:0046889=IMP, GO:0030163=IEA, GO:0046329=IEA, GO:0046777=TAS, GO:1901976=TAS, GO:1900740=TAS, GO:0008637=IEA, GO:0060644=TAS, GO:0015758=IEA, GO:0018105=IDA, GO:0046326=IMP, GO:0005080=IEA, GO:0060716=IEA, GO:0000060=IMP, GO:0005979=IMP, GO:0032869=ISS, GO:0005978=IEA, GO:0005819=IEA, GO:0001893=IEA, GO:0010748=IMP, GO:0030168=TAS, GO:0070141=IDA, GO:0032270=ISS, GO:0051000=IMP, GO:0045087=TAS, GO:0051146=IEA, GO:0016044=TAS, GO:0016567=IEA, GO:0050999=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0032094=IEA, GO:0005829=TAS, GO:0032880=IEA, GO:0051091=IDA, GO:0033138=IDA, GO:0006954=IEA, GO:0045907=IEA, GO:0006006=IEA, GO:0046209=TAS, GO:0030235=IMP, GO:0043154=ISS, GO:0048011=TAS, GO:0045725=NAS, GO:0043325=IDA, GO:0048015=TAS, GO:0071456=IEA, GO:0042593=IEA, GO:0032287=IEA, GO:0006417=IEA, GO:0045861=IMP, GO:0004672=TAS, GO:0071364=IEA, GO:0004674=IDA, GO:0007596=TAS, GO:0048009=IMP, GO:0010467=TAS, GO:0009408=TAS, GO:0034405=IMP, GO:0006412=IEA, GO:0010907=IMP, GO:0006809=TAS, GO:0042802=IPI, GO:0007173=TAS, GO:0010765=IEA, GO:0016301=IDA, GO:0030334=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0007568=IEA, GO:0005547=IDA, GO:0030027=IEA, GO:0001649=IEA, GO:0043536=IDA, GO:0016310=IDA, GO:0045792=IEA, GO:0007186=TAS, GO:0008543=TAS, GO:0010975=ISS, GO:0030030=IEA, GO:0010507=IMP, GO:0045600=IMP, GO:0043491=IEA, GO:0005654=TAS, GO:0019899=ISS, GO:0008286=IMP, GO:0005886=TAS, GO:0031999=IMP, GO:0008283=TAS, GO:0031295=TAS, GO:0032436=IEA, GO:0006924=IMP, GO:0045429=IMP, GO:0035556=IDA, GO:0005737=ISS, GO:0005543=IEA, GO:0090201=ISS, GO:0045944=IEA, GO:0015630=IDA, GO:0060709=IEA, GO:0043066=NAS, GO:0043065=IEA, GO:0006915=TAS, GO:0005524=IDA, GO:0097193=TAS, GO:0010951=IMP, GO:0007165=TAS, GO:0031659=IDA, GO:0031018=TAS, GO:0001934=IDA, GO:0006468=IDA, GO:0006469=ISS, GO:0006464=TAS, GO:0090004=IMP} G-protein coupled receptor signaling pathway, RNA metabolic process, T cell costimulation, activation-induced cell death of T cells, aging, anagen, apoptotic mitochondrial changes, apoptotic process, blood coagulation, cell differentiation, cell projection organization, cell proliferation, cellular membrane organization, cellular protein modification process, cellular response to epidermal growth factor stimulus, cellular response to hypoxia, cellular response to insulin stimulus, endocrine pancreas development, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, gene expression, germ cell development, glucose homeostasis, glucose metabolic process, glucose transport, glycogen biosynthetic process, glycogen cell differentiation involved in embryonic placenta development, inflammatory response, innate immune response, insulin receptor signaling pathway, insulin-like growth factor receptor signaling pathway, intracellular signal transduction, intrinsic apoptotic signaling pathway, labyrinthine layer blood vessel development, mRNA metabolic process, mammary gland epithelial cell differentiation, maternal placenta development, negative regulation of JNK cascade, negative regulation of apoptotic process, negative regulation of autophagy, negative regulation of cell size, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of endopeptidase activity, negative regulation of fatty acid beta-oxidation, negative regulation of plasma membrane long-chain fatty acid transport, negative regulation of protein kinase activity, negative regulation of proteolysis, negative regulation of release of cytochrome c from mitochondria, neurotrophin TRK receptor signaling pathway, nitric oxide biosynthetic process, nitric oxide metabolic process, osteoblast differentiation, peptidyl-serine phosphorylation, peripheral nervous system myelin maintenance, phosphatidylinositol-mediated signaling, phosphorylation, platelet activation, positive regulation of apoptotic process, positive regulation of blood vessel endothelial cell migration, positive regulation of cell growth, positive regulation of cellular protein metabolic process, positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S, positive regulation of establishment of protein localization to plasma membrane, positive regulation of fat cell differentiation, positive regulation of glucose import, positive regulation of glucose metabolic process, positive regulation of glycogen biosynthetic process, positive regulation of lipid biosynthetic process, positive regulation of nitric oxide biosynthetic process, positive regulation of nitric-oxide synthase activity, positive regulation of peptidyl-serine phosphorylation, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, positive regulation of protein phosphorylation, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of sodium ion transport, positive regulation of transcription from RNA polymerase II promoter, positive regulation of vasoconstriction, protein autophosphorylation, protein catabolic process, protein import into nucleus, translocation, protein kinase B signaling cascade, protein phosphorylation, protein ubiquitination, regulation of cell cycle checkpoint, regulation of cell migration, regulation of glycogen biosynthetic process, regulation of neuron projection development, regulation of nitric-oxide synthase activity, regulation of protein localization, regulation of translation, response to UV-A, response to fluid shear stress, response to food, response to heat, signal transduction, small molecule metabolic process, striated muscle cell differentiation, translation cytoplasm, cytosol, lamellipodium, microtubule cytoskeleton, nucleoplasm, nucleus, plasma membrane, spindle ATP binding, enzyme binding, identical protein binding, kinase activity, nitric-oxide synthase regulator activity, phosphatidylinositol-3,4,5-trisphosphate binding, phosphatidylinositol-3,4-bisphosphate binding, phospholipid binding, protein binding, protein kinase C binding, protein kinase activity, protein serine/threonine kinase activity Human AKT1S1 Reactome UniProtKB {GO:0005515=PMID:17386266, GO:0032007=PMID:17386266, GO:0048011=Reactome:REACT_11061, GO:0048015=Reactome:REACT_12464, GO:0005634=GO_REF:0000019, GO:0005829=Reactome:REACT_147737, GO:0044445=GO_REF:0000024, GO:0043234=GO_REF:0000019, GO:0043523=GO_REF:0000024, GO:0045792=PMID:17386266, GO:0031931=PMID:17386266, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0006469=PMID:17386266} Q96B36 Proline-rich AKT1 substrate 1 protein 20130301 {GO:0005515=IPI, GO:0032007=IDA, GO:0048011=TAS, GO:0048015=TAS, GO:0005634=IEA, GO:0005829=TAS, GO:0044445=ISS, GO:0043234=IEA, GO:0043523=ISS, GO:0045792=IDA, GO:0031931=IDA, GO:0007173=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0006469=IDA} epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, negative regulation of TOR signaling cascade, negative regulation of cell size, negative regulation of protein kinase activity, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, regulation of neuron apoptotic process TORC1 complex, cytosol, cytosolic part, nucleus, protein complex protein binding Human AKT2 UniProtKB UniProtKB {GO:0008286=PMID:16814735, GO:0005515=PMID:22939624, GO:0071156=PMID:21432781, GO:0032859=GO_REF:0000019, GO:0005886=GO_REF:0000024, GO:0031340=GO_REF:0000024, GO:0008643=GO_REF:0000037, GO:0005634=PMID:21432781, GO:2000147=PMID:17332325, GO:0010907=PMID:16814735, GO:0005829=Reactome:REACT_6952, GO:0046328=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0060644=PMID:21432781, GO:0016301=Reactome:REACT_6952, GO:0046326=PMID:16814735, GO:0006006=GO_REF:0000037, GO:0045444=PMID:21432781, GO:0005938=GO_REF:0000024, GO:0030334=PMID:21432781, GO:0032869=PMID:16814735, GO:0045725=PMID:16814735, GO:0005978=GO_REF:0000037, GO:0090314=GO_REF:0000024, GO:0006915=GO_REF:0000037, GO:0010748=PMID:16814735, GO:0032587=GO_REF:0000024, GO:0005524=GO_REF:0000038, GO:0072659=GO_REF:0000019, GO:0006417=GO_REF:0000037, GO:0032287=GO_REF:0000019, GO:0030027=GO_REF:0000019, GO:0065002=GO_REF:0000024, GO:2001275=GO_REF:0000019, GO:0007165=PMID:21432781, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000038, GO:0032000=PMID:16814735, GO:0001934=GO_REF:0000024, GO:0016044=Reactome:REACT_11123, GO:0006464=PMID:1409633} Q0VAN0 RAC-beta serine/threonine-protein kinase protein 20130413 {GO:0008286=IMP, GO:0005515=IPI, GO:0071156=TAS, GO:0032859=IEA, GO:0005886=ISS, GO:0031340=ISS, GO:0008643=IEA, GO:0005634=TAS, GO:2000147=IMP, GO:0010907=IMP, GO:0005829=TAS, GO:0046328=IEA, GO:0005543=IEA, GO:0060644=TAS, GO:0016301=TAS, GO:0046326=IMP, GO:0006006=IEA, GO:0045444=TAS, GO:0005938=ISS, GO:0030334=TAS, GO:0032869=IMP, GO:0045725=IMP, GO:0005978=IEA, GO:0090314=ISS, GO:0006915=IEA, GO:0010748=IMP, GO:0032587=ISS, GO:0005524=IEA, GO:0072659=IEA, GO:0006417=IEA, GO:0032287=IEA, GO:0030027=IEA, GO:0065002=ISS, GO:2001275=IEA, GO:0007165=TAS, GO:0004672=IEA, GO:0004674=IEA, GO:0032000=IMP, GO:0001934=ISS, GO:0016044=TAS, GO:0006464=TAS} activation of Ral GTPase activity, apoptotic process, carbohydrate transport, cellular membrane organization, cellular protein modification process, cellular response to insulin stimulus, fat cell differentiation, glucose metabolic process, glycogen biosynthetic process, insulin receptor signaling pathway, intracellular protein transmembrane transport, mammary gland epithelial cell differentiation, negative regulation of plasma membrane long-chain fatty acid transport, peripheral nervous system myelin maintenance, positive regulation of cell motility, positive regulation of fatty acid beta-oxidation, positive regulation of glucose import, positive regulation of glucose import in response to insulin stimulus, positive regulation of glucose metabolic process, positive regulation of glycogen biosynthetic process, positive regulation of protein phosphorylation, positive regulation of protein targeting to membrane, positive regulation of vesicle fusion, protein localization to plasma membrane, regulation of JNK cascade, regulation of cell cycle arrest, regulation of cell migration, regulation of translation, signal transduction cell cortex, cytosol, lamellipodium, nucleus, plasma membrane, ruffle membrane ATP binding, kinase activity, phospholipid binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB-KW:KW-0067 AKT3 HPA UniProtKB {GO:0005515=PMID:19713527, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005524=PMID:16540465, GO:0007165=PMID:18524868, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0004672=PMID:10092583, GO:0004674=PMID:16540465, GO:0006468=PMID:10092583, GO:0000002=PMID:18524868} Q9Y243 RAC-gamma serine/threonine-protein kinase protein 20101115 {GO:0005515=IPI, GO:0005794=IDA, GO:0005886=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0005524=IDA, GO:0007165=IMP, GO:0005737=IDA, GO:0005543=IEA, GO:0004672=TAS, GO:0004674=IDA, GO:0006468=TAS, GO:0000002=IMP} mitochondrial genome maintenance, protein phosphorylation, signal transduction Golgi apparatus, cytoplasm, nucleolus, nucleus, plasma membrane ATP binding, phospholipid binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human AKTIP HPA UniProtKB {GO:0005515=PMID:18799622, GO:0030897=PMID:18799622, GO:0005794=GO_REF:0000052, GO:0016881=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0008333=PMID:18799622, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0045022=PMID:18799622, GO:0032092=PMID:14749367, GO:0005737=GO_REF:0000052, GO:0019787=PMID:18799622, GO:0001934=PMID:14749367, GO:0007032=PMID:18799622, GO:0007040=PMID:18799622, GO:0070695=PMID:18799622} Q9H8T0 AKT-interacting protein protein 20120912 {GO:0005515=IPI, GO:0030897=IDA, GO:0005794=IDA, GO:0016881=IEA, GO:0005886=IDA, GO:0008333=IMP, GO:0005730=IDA, GO:0006915=IEA, GO:0015031=IEA, GO:0045022=IMP, GO:0032092=IDA, GO:0005737=IDA, GO:0019787=NAS, GO:0001934=IDA, GO:0007032=IMP, GO:0007040=IMP, GO:0070695=IDA} apoptotic process, early endosome to late endosome transport, endosome organization, endosome to lysosome transport, lysosome organization, positive regulation of protein binding, positive regulation of protein phosphorylation, protein transport FHF complex, Golgi apparatus, HOPS complex, cytoplasm, nucleolus, plasma membrane acid-amino acid ligase activity, protein binding, small conjugating protein ligase activity Human ALAD Reactome UniProtKB {GO:0032791=PMID:11032836, GO:0044281=Reactome:REACT_111217, GO:0004655=Reactome:REACT_9430, GO:0033014=GO_REF:0000002, GO:0006782=GO_REF:0000041, GO:0003824=PMID:2063868, GO:0046872=GO_REF:0000002, GO:0042802=PMID:11032836, GO:0006783=Reactome:REACT_9465, GO:0005829=Reactome:REACT_9437, GO:0006778=Reactome:REACT_9431, GO:0006779=GO_REF:0000038, GO:0008270=PMID:11032836, GO:0051260=PMID:11032836} P13716 Delta-aminolevulinic acid dehydratase protein 20080604 {GO:0032791=IDA, GO:0044281=TAS, GO:0004655=TAS, GO:0033014=IEA, GO:0006782=IEA, GO:0003824=TAS, GO:0046872=IEA, GO:0042802=IPI, GO:0006783=TAS, GO:0005829=TAS, GO:0006778=TAS, GO:0006779=IEA, GO:0008270=IDA, GO:0051260=IPI} heme biosynthetic process, porphyrin-containing compound biosynthetic process, porphyrin-containing compound metabolic process, protein homooligomerization, protoporphyrinogen IX biosynthetic process, small molecule metabolic process, tetrapyrrole biosynthetic process cytosol catalytic activity, identical protein binding, lead ion binding, metal ion binding, porphobilinogen synthase activity, zinc ion binding Human ALAS1 HPA UniProtKB {GO:0009058=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0006782=GO_REF:0000041, GO:0006783=Reactome:REACT_9465, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0006778=Reactome:REACT_9431, GO:0005759=Reactome:REACT_115949, GO:0030170=GO_REF:0000002, GO:0003870=GO_REF:0000003, GO:0044255=Reactome:REACT_22279} P13196 5-aminolevulinate synthase, nonspecific, mitochondrial protein 20110516 {GO:0009058=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0003824=IEA, GO:0006782=IEA, GO:0006783=TAS, GO:0005739=IDA, GO:0005737=IDA, GO:0006778=TAS, GO:0005759=TAS, GO:0030170=IEA, GO:0003870=IEA, GO:0044255=TAS} biosynthetic process, cellular lipid metabolic process, heme biosynthetic process, porphyrin-containing compound metabolic process, protoporphyrinogen IX biosynthetic process, small molecule metabolic process cytoplasm, mitochondrial matrix, mitochondrion, nucleolus, nucleus 5-aminolevulinate synthase activity, catalytic activity, pyridoxal phosphate binding Human ALAS2 InterPro UniProtKB {GO:0042541=GO_REF:0000024, GO:0005515=PMID:14643893, GO:0050662=GO_REF:0000024, GO:0001666=PMID:16234850, GO:0009058=GO_REF:0000002, GO:0005743=PMID:14643893, GO:0044281=Reactome:REACT_111217, GO:0033014=GO_REF:0000002, GO:0006782=GO_REF:0000041, GO:0006783=Reactome:REACT_9465, GO:0006879=GO_REF:0000024, GO:0005739=PMID:10727444, GO:0006778=GO_REF:0000002, GO:0005759=GO_REF:0000002, GO:0030170=GO_REF:0000002, GO:0030218=PMID:2050125, GO:0016594=GO_REF:0000024, GO:0003870=GO_REF:0000002, GO:0032364=PMID:16234850} Q5JZF5 Aminolevulinate, delta-, synthase 2 (Sideroblastic/hypochromic anemia), isoform CRA_a protein 20130413 {GO:0042541=ISS, GO:0005515=IPI, GO:0050662=ISS, GO:0001666=IDA, GO:0009058=IEA, GO:0005743=IDA, GO:0044281=TAS, GO:0033014=IEA, GO:0006782=IEA, GO:0006783=TAS, GO:0006879=ISS, GO:0005739=IDA, GO:0006778=IEA, GO:0005759=IEA, GO:0030170=IEA, GO:0030218=NAS, GO:0016594=ISS, GO:0003870=IEA, GO:0032364=NAS} biosynthetic process, cellular iron ion homeostasis, erythrocyte differentiation, heme biosynthetic process, hemoglobin biosynthetic process, oxygen homeostasis, porphyrin-containing compound metabolic process, protoporphyrinogen IX biosynthetic process, response to hypoxia, small molecule metabolic process, tetrapyrrole biosynthetic process mitochondrial inner membrane, mitochondrial matrix, mitochondrion 5-aminolevulinate synthase activity, coenzyme binding, glycine binding, protein binding, pyridoxal phosphate binding Human InterPro:IPR010961 ALB BHF-UCL UniProtKB {GO:0006629=Reactome:REACT_602, GO:0005515=PMID:16099937, GO:0043498=GO_REF:0000019, GO:0051087=PMID:19996109, GO:0043252=Reactome:REACT_23988, GO:0044281=Reactome:REACT_111217, GO:0005615=PMID:19996109, GO:0043069=PMID:14726550, GO:0019836=PMID:16394536, GO:0008144=PMID:10940303, GO:0006810=PMID:12617161, GO:0031093=Reactome:REACT_21351, GO:0008206=Reactome:REACT_11040, GO:0046010=GO_REF:0000019, GO:0009267=PMID:16245148, GO:0005504=PMID:9731778, GO:0043066=PMID:16153637, GO:0010033=GO_REF:0000019, GO:0016209=PMID:14726550, GO:0005507=PMID:14726550, GO:0007584=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_160182, GO:0055085=Reactome:REACT_19118, GO:0003677=PMID:16405401, GO:0005604=GO_REF:0000019, GO:0043234=PMID:16283771, GO:0019825=PMID:16283771, GO:0007596=Reactome:REACT_604, GO:0015721=Reactome:REACT_11042, GO:0030170=PMID:16201370, GO:0015643=PMID:16169013, GO:0002576=Reactome:REACT_318, GO:0042157=Reactome:REACT_13621, GO:0008270=GO_REF:0000019, GO:0051659=PMID:16153637, GO:0070541=GO_REF:0000019, GO:0019899=GO_REF:0000019, GO:0046689=GO_REF:0000019} P02768 Serum albumin protein 20100113 {GO:0006629=TAS, GO:0005515=IPI, GO:0043498=IEA, GO:0051087=IPI, GO:0043252=TAS, GO:0044281=TAS, GO:0005615=IDA, GO:0043069=NAS, GO:0019836=IDA, GO:0008144=NAS, GO:0006810=TAS, GO:0031093=TAS, GO:0008206=TAS, GO:0046010=IEA, GO:0009267=IDA, GO:0005504=NAS, GO:0043066=IDA, GO:0010033=IEA, GO:0016209=NAS, GO:0005507=NAS, GO:0007584=IEA, GO:0030168=TAS, GO:0005576=TAS, GO:0055085=TAS, GO:0003677=IDA, GO:0005604=IEA, GO:0043234=IDA, GO:0019825=IDA, GO:0007596=TAS, GO:0015721=TAS, GO:0030170=IDA, GO:0015643=IDA, GO:0002576=TAS, GO:0042157=TAS, GO:0008270=IEA, GO:0051659=IDA, GO:0070541=IEA, GO:0019899=IEA, GO:0046689=IEA} bile acid and bile salt transport, bile acid metabolic process, blood coagulation, cellular response to starvation, hemolysis by symbiont of host erythrocytes, lipid metabolic process, lipoprotein metabolic process, maintenance of mitochondrion location, negative regulation of apoptotic process, negative regulation of programmed cell death, platelet activation, platelet degranulation, positive regulation of circadian sleep/wake cycle, non-REM sleep, response to mercury ion, response to nutrient, response to organic substance, response to platinum ion, small molecule metabolic process, sodium-independent organic anion transport, transmembrane transport, transport basement membrane, extracellular region, extracellular space, platelet alpha granule lumen, protein complex DNA binding, antioxidant activity, cell surface binding, chaperone binding, copper ion binding, drug binding, enzyme binding, fatty acid binding, oxygen binding, protein binding, pyridoxal phosphate binding, toxic substance binding, zinc ion binding Human ALCAM UniProtKB UniProtKB {GO:0007165=PMID:7760007, GO:0030424=GO_REF:0000019, GO:0008045=GO_REF:0000019, GO:0016020=GO_REF:0000038, GO:0007411=Reactome:REACT_18266, GO:0005102=PMID:7760007, GO:0043025=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037, GO:0009897=GO_REF:0000019} Q6ZS95 cDNA FLJ45715 fis, clone FELNG2000720, highly similar to CD166 antigen protein 20130413 {GO:0007165=TAS, GO:0030424=IEA, GO:0008045=IEA, GO:0016020=IEA, GO:0007411=TAS, GO:0005102=TAS, GO:0043025=IEA, GO:0016021=IEA, GO:0007155=IEA, GO:0009897=IEA} axon guidance, cell adhesion, motor neuron axon guidance, signal transduction axon, external side of plasma membrane, integral to membrane, membrane, neuronal cell body receptor binding Human UniProtKB-KW:KW-0472 ALDH16A1 InterPro UniProtKB {GO:0016620=GO_REF:0000002} Q8IZ83 Aldehyde dehydrogenase family 16 member A1 protein 20130413 {GO:0016620=IEA} oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Human InterPro:IPR016163 ALDH18A1 HPA UniProtKB {GO:0019240=PMID:11092761, GO:0006536=PMID:11092761, GO:0055129=GO_REF:0000041, GO:0005743=Reactome:REACT_21319, GO:0004349=PMID:11092761, GO:0008652=Reactome:REACT_238, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0005739=GO_REF:0000052, GO:0034641=Reactome:REACT_13, GO:0004350=PMID:11092761, GO:0005737=GO_REF:0000052, GO:0006592=PMID:11092761, GO:0006561=PMID:11092761} P54886 Delta-1-pyrroline-5-carboxylate synthase protein 20090616 {GO:0019240=IMP, GO:0006536=IMP, GO:0055129=IEA, GO:0005743=TAS, GO:0004349=IDA, GO:0008652=TAS, GO:0044281=TAS, GO:0005524=IEA, GO:0005739=IDA, GO:0034641=TAS, GO:0004350=IDA, GO:0005737=IDA, GO:0006592=IMP, GO:0006561=IMP} L-proline biosynthetic process, cellular amino acid biosynthetic process, cellular nitrogen compound metabolic process, citrulline biosynthetic process, glutamate metabolic process, ornithine biosynthetic process, proline biosynthetic process, small molecule metabolic process cytoplasm, mitochondrial inner membrane, mitochondrion ATP binding, glutamate 5-kinase activity, glutamate-5-semialdehyde dehydrogenase activity Human ALDH1A1 InterPro UniProtKB {GO:0006805=Reactome:REACT_13705, GO:0001758=GO_REF:0000003, GO:0006069=Reactome:REACT_34, GO:0006081=PMID:1709013, GO:0004029=Reactome:REACT_2127, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_2127, GO:0005099=PMID:1709013, GO:0005737=PMID:2987944, GO:0032320=PMID:1709013, GO:0042572=GO_REF:0000041, GO:0016491=GO_REF:0000002, GO:0005497=PMID:1709013} Q5SYQ9 Retinal dehydrogenase 1 protein 20130413 {GO:0006805=TAS, GO:0001758=IEA, GO:0006069=TAS, GO:0006081=TAS, GO:0004029=EXP, GO:0044281=TAS, GO:0005829=TAS, GO:0005099=TAS, GO:0005737=TAS, GO:0032320=TAS, GO:0042572=IEA, GO:0016491=IEA, GO:0005497=TAS} cellular aldehyde metabolic process, ethanol oxidation, positive regulation of Ras GTPase activity, retinol metabolic process, small molecule metabolic process, xenobiotic metabolic process cytoplasm, cytosol Ras GTPase activator activity, aldehyde dehydrogenase (NAD) activity, androgen binding, oxidoreductase activity, retinal dehydrogenase activity Human InterPro:IPR015590|InterPro:IPR016161|InterPro:IPR016162 ALDH1A2 HPA UniProtKB {GO:0048471=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0008285=PMID:16166285, GO:0001758=GO_REF:0000024, GO:0071300=GO_REF:0000019, GO:0030324=GO_REF:0000019, GO:0033189=GO_REF:0000019, GO:0021983=GO_REF:0000019, GO:0016918=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0009954=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0031076=GO_REF:0000019, GO:0014032=GO_REF:0000019, GO:0042574=GO_REF:0000019, GO:0006776=PMID:8663198, GO:0042573=GO_REF:0000024, GO:0030182=GO_REF:0000019, GO:0042572=GO_REF:0000041, GO:0034097=PMID:18495959, GO:0032355=GO_REF:0000019, GO:0035799=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0001568=GO_REF:0000019, GO:0001822=GO_REF:0000019, GO:0004028=GO_REF:0000024, GO:0048566=GO_REF:0000019, GO:0048384=GO_REF:0000019, GO:0048738=GO_REF:0000019, GO:0010628=GO_REF:0000019, GO:0001889=GO_REF:0000019, GO:0003007=GO_REF:0000019, GO:0016331=GO_REF:0000019, GO:0031016=GO_REF:0000019, GO:0007494=GO_REF:0000019, GO:0001936=GO_REF:0000019, GO:0016620=GO_REF:0000002, GO:0060324=GO_REF:0000019, GO:0042904=GO_REF:0000019, GO:0021915=PMID:16237707, GO:0035115=GO_REF:0000019, GO:0030902=GO_REF:0000019, GO:0009855=GO_REF:0000019} O94788 Retinal dehydrogenase 2 protein 20101115 {GO:0048471=IEA, GO:0008284=IEA, GO:0008285=IDA, GO:0001758=ISS, GO:0071300=IEA, GO:0030324=IEA, GO:0033189=IEA, GO:0021983=IEA, GO:0016918=ISS, GO:0005634=IDA, GO:0009954=IEA, GO:0009952=IEA, GO:0005829=IEA, GO:0005737=IDA, GO:0031076=IEA, GO:0014032=IEA, GO:0042574=IEA, GO:0006776=NAS, GO:0042573=ISS, GO:0030182=IEA, GO:0042572=IEA, GO:0034097=IDA, GO:0032355=IEA, GO:0035799=IEA, GO:0043065=IEA, GO:0001568=IEA, GO:0001822=IEA, GO:0004028=ISS, GO:0048566=IEA, GO:0048384=IEA, GO:0048738=IEA, GO:0010628=IEA, GO:0001889=IEA, GO:0003007=IEA, GO:0016331=IEA, GO:0031016=IEA, GO:0007494=IEA, GO:0001936=IEA, GO:0016620=IEA, GO:0060324=IEA, GO:0042904=IEA, GO:0021915=IMP, GO:0035115=IEA, GO:0030902=IEA, GO:0009855=IEA} 9-cis-retinoic acid biosynthetic process, anterior/posterior pattern specification, blood vessel development, cardiac muscle tissue development, cellular response to retinoic acid, determination of bilateral symmetry, embryonic camera-type eye development, embryonic digestive tract development, embryonic forelimb morphogenesis, face development, heart morphogenesis, hindbrain development, kidney development, liver development, lung development, midgut development, morphogenesis of embryonic epithelium, negative regulation of cell proliferation, neural crest cell development, neural tube development, neuron differentiation, pancreas development, pituitary gland development, positive regulation of apoptotic process, positive regulation of cell proliferation, positive regulation of gene expression, proximal/distal pattern formation, regulation of endothelial cell proliferation, response to cytokine stimulus, response to estradiol stimulus, response to vitamin A, retinal metabolic process, retinoic acid metabolic process, retinoic acid receptor signaling pathway, retinol metabolic process, ureter maturation, vitamin A metabolic process cytoplasm, cytosol, nucleus, perinuclear region of cytoplasm 3-chloroallyl aldehyde dehydrogenase activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, retinal binding, retinal dehydrogenase activity Human ALDH1A3 UniProtKB UniProtKB {GO:0043065=GO_REF:0000019, GO:0004029=GO_REF:0000019, GO:0070403=GO_REF:0000019, GO:0070324=GO_REF:0000019, GO:0042803=PMID:11585737, GO:0005737=PMID:11585737, GO:0042574=PMID:11585737, GO:0042573=PMID:11585737, GO:0016620=GO_REF:0000002, GO:0060324=GO_REF:0000019, GO:0042572=GO_REF:0000041, GO:0060166=GO_REF:0000019, GO:0016491=GO_REF:0000002, GO:0002072=GO_REF:0000019, GO:0002138=GO_REF:0000019, GO:0048048=GO_REF:0000024, GO:0004030=PMID:11585737, GO:0021768=GO_REF:0000019} P47895 Aldehyde dehydrogenase family 1 member A3 protein 20090316 {GO:0043065=IEA, GO:0004029=IEA, GO:0070403=IEA, GO:0070324=IEA, GO:0042803=IDA, GO:0005737=IDA, GO:0042574=IDA, GO:0042573=IDA, GO:0016620=IEA, GO:0060324=IEA, GO:0042572=IEA, GO:0060166=IEA, GO:0016491=IEA, GO:0002072=IEA, GO:0002138=IEA, GO:0048048=ISS, GO:0004030=IDA, GO:0021768=IEA} embryonic eye morphogenesis, face development, nucleus accumbens development, olfactory pit development, optic cup morphogenesis involved in camera-type eye development, positive regulation of apoptotic process, retinal metabolic process, retinoic acid biosynthetic process, retinoic acid metabolic process, retinol metabolic process cytoplasm "NAD+ binding, aldehyde dehydrogenase (NAD) activity, aldehyde dehydrogenase NAD(P)+"" activity, oxidoreductase activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, protein homodimerization activity, thyroid hormone binding""" Human UniProtKB:Q9JHW9 ALDH1B1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005975=PMID:1306115, GO:0005759=GO_REF:0000039, GO:0006068=GO_REF:0000041, GO:0005730=GO_REF:0000052, GO:0004029=GO_REF:0000003, GO:0005634=GO_REF:0000052, GO:0043231=GO_REF:0000052} P30837 Aldehyde dehydrogenase X, mitochondrial protein 20101115 {GO:0005739=IDA, GO:0005975=NAS, GO:0005759=IEA, GO:0006068=IEA, GO:0005730=IDA, GO:0004029=IEA, GO:0005634=IDA, GO:0043231=IDA} carbohydrate metabolic process, ethanol catabolic process intracellular membrane-bounded organelle, mitochondrial matrix, mitochondrion, nucleolus, nucleus aldehyde dehydrogenase (NAD) activity Human ALDH1L1 InterPro UniProtKB {GO:0005739=GO_REF:0000019, GO:0016155=GO_REF:0000003, GO:0009058=GO_REF:0000002, GO:0016620=GO_REF:0000002, GO:0008168=GO_REF:0000002, GO:0016491=GO_REF:0000002, GO:0003824=PMID:10204077, GO:0016742=GO_REF:0000002, GO:0006730=GO_REF:0000037, GO:0009258=GO_REF:0000002} Q8TBP8 Cytosolic 10-formyltetrahydrofolate dehydrogenase protein 20130413 {GO:0005739=IEA, GO:0016155=IEA, GO:0009058=IEA, GO:0016620=IEA, GO:0008168=IEA, GO:0016491=IEA, GO:0003824=TAS, GO:0016742=IEA, GO:0006730=IEA, GO:0009258=IEA} 10-formyltetrahydrofolate catabolic process, biosynthetic process, one-carbon metabolic process mitochondrion catalytic activity, formyltetrahydrofolate dehydrogenase activity, hydroxymethyl-, formyl- and related transferase activity, methyltransferase activity, oxidoreductase activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Human InterPro:IPR002376|InterPro:IPR005793 ALDH1L2 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0016155=GO_REF:0000003, GO:0009058=GO_REF:0000002, GO:0008168=GO_REF:0000002, GO:0016620=GO_REF:0000002, GO:0016742=GO_REF:0000002, GO:0006730=GO_REF:0000037, GO:0009258=GO_REF:0000002} Q3SY69 Mitochondrial 10-formyltetrahydrofolate dehydrogenase protein 20111111 {GO:0005739=IDA, GO:0016155=IEA, GO:0009058=IEA, GO:0008168=IEA, GO:0016620=IEA, GO:0016742=IEA, GO:0006730=IEA, GO:0009258=IEA} 10-formyltetrahydrofolate catabolic process, biosynthetic process, one-carbon metabolic process mitochondrion formyltetrahydrofolate dehydrogenase activity, hydroxymethyl-, formyl- and related transferase activity, methyltransferase activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Human ALDH2 Reactome UniProtKB {GO:0006805=Reactome:REACT_13705, GO:0005975=PMID:8903321, GO:0006066=PMID:1306115, GO:0006069=Reactome:REACT_34, GO:0006068=GO_REF:0000041, GO:0004029=Reactome:REACT_15407, GO:0009055=PMID:8903321, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0005759=Reactome:REACT_15407, GO:0016620=GO_REF:0000002, GO:0042136=Reactome:REACT_13583, GO:0004030=PMID:8903321} P05091 Aldehyde dehydrogenase, mitochondrial protein 20130213 {GO:0006805=TAS, GO:0005975=TAS, GO:0006066=TAS, GO:0006069=TAS, GO:0006068=IEA, GO:0004029=EXP, GO:0009055=TAS, GO:0007268=TAS, GO:0044281=TAS, GO:0005759=TAS, GO:0016620=IEA, GO:0042136=TAS, GO:0004030=TAS} alcohol metabolic process, carbohydrate metabolic process, ethanol catabolic process, ethanol oxidation, neurotransmitter biosynthetic process, small molecule metabolic process, synaptic transmission, xenobiotic metabolic process mitochondrial matrix "aldehyde dehydrogenase (NAD) activity, aldehyde dehydrogenase NAD(P)+"" activity, electron carrier activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor""" Human ALDH3A1 LIFEdb UniProtKB {GO:0001666=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0005783=GO_REF:0000054, GO:0007584=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0006081=PMID:1737758, GO:0004029=PMID:1737758, GO:0004028=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0051591=GO_REF:0000019, GO:0005829=GO_REF:0000024, GO:0008106=PMID:1737758, GO:0055114=PMID:1737758, GO:0004030=GO_REF:0000003} P30838 Aldehyde dehydrogenase, dimeric NADP-preferring protein 20100607 {GO:0001666=IEA, GO:0008284=IEA, GO:0005783=IDA, GO:0007584=IEA, GO:0042493=IEA, GO:0007568=IEA, GO:0006081=IDA, GO:0004029=IDA, GO:0004028=IEA, GO:0051384=IEA, GO:0051591=IEA, GO:0005829=ISS, GO:0008106=IDA, GO:0055114=IDA, GO:0004030=IEA} aging, cellular aldehyde metabolic process, oxidation-reduction process, positive regulation of cell proliferation, response to cAMP, response to drug, response to glucocorticoid stimulus, response to hypoxia, response to nutrient cytosol, endoplasmic reticulum "3-chloroallyl aldehyde dehydrogenase activity, alcohol dehydrogenase (NADP+) activity, aldehyde dehydrogenase (NAD) activity, aldehyde dehydrogenase NAD(P)+"" activity""" Human ALDH3A2 UniProtKB UniProtKB {GO:0005783=GO_REF:0000019, GO:0006081=PMID:8528251, GO:0005743=GO_REF:0000019, GO:0004029=PMID:9133646, GO:0046577=PMID:18035827, GO:0007417=PMID:8528251, GO:0043231=PMID:9133646, GO:0008544=PMID:8528251, GO:0007422=PMID:8528251, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0033306=PMID:15110319, GO:0004030=GO_REF:0000002, GO:0055114=PMID:9133646} P51648 Fatty aldehyde dehydrogenase protein 20120416 {GO:0005783=IEA, GO:0006081=NAS, GO:0005743=IEA, GO:0004029=IDA, GO:0046577=IDA, GO:0007417=IMP, GO:0043231=IDA, GO:0008544=IMP, GO:0007422=IMP, GO:0005789=IEA, GO:0016021=IEA, GO:0033306=IMP, GO:0004030=IEA, GO:0055114=IDA} cellular aldehyde metabolic process, central nervous system development, epidermis development, oxidation-reduction process, peripheral nervous system development, phytol metabolic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle, mitochondrial inner membrane "aldehyde dehydrogenase (NAD) activity, aldehyde dehydrogenase NAD(P)+"" activity, long-chain-alcohol oxidase activity""" Human ALDH3B1 MGI UniProtKB {GO:0006629=PMID:7828891, GO:0005737=PMID:20699116, GO:0006066=PMID:7828891, GO:0046185=PMID:20699116, GO:0006068=GO_REF:0000041, GO:0004028=PMID:7828891, GO:0034599=PMID:20699116, GO:0055114=PMID:20699116, GO:0004030=PMID:20699116} P43353 Aldehyde dehydrogenase family 3 member B1 protein 20120109 {GO:0006629=TAS, GO:0005737=IDA, GO:0006066=TAS, GO:0046185=IDA, GO:0006068=IEA, GO:0004028=TAS, GO:0034599=IDA, GO:0055114=IDA, GO:0004030=IDA} alcohol metabolic process, aldehyde catabolic process, cellular response to oxidative stress, ethanol catabolic process, lipid metabolic process, oxidation-reduction process cytoplasm "3-chloroallyl aldehyde dehydrogenase activity, aldehyde dehydrogenase NAD(P)+"" activity""" Human ALDH3B2 PINC UniProtKB {GO:0006629=PMID:8890755, GO:0006066=PMID:8890755, GO:0006068=GO_REF:0000041, GO:0006081=GO_REF:0000002, GO:0004028=PMID:8890755, GO:0004030=GO_REF:0000003} P48448 Aldehyde dehydrogenase family 3 member B2 protein 20030904 {GO:0006629=TAS, GO:0006066=TAS, GO:0006068=IEA, GO:0006081=IEA, GO:0004028=TAS, GO:0004030=IEA} alcohol metabolic process, cellular aldehyde metabolic process, ethanol catabolic process, lipid metabolic process "3-chloroallyl aldehyde dehydrogenase activity, aldehyde dehydrogenase NAD(P)+"" activity""" Human ALDH4A1 InterPro UniProtKB {GO:0004029=PMID:8621661, GO:0009055=PMID:8621661, GO:0044281=Reactome:REACT_111217, GO:0003842=Reactome:REACT_2180, GO:0042802=PMID:22516612, GO:0034641=Reactome:REACT_13, GO:0019470=PMID:21998747, GO:0006560=PMID:8621661, GO:0005759=Reactome:REACT_2180, GO:0016620=GO_REF:0000002, GO:0010133=GO_REF:0000041, GO:0016491=GO_REF:0000002, GO:0006562=Reactome:REACT_1002, GO:0006561=GO_REF:0000002} Q5TF55 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial protein 20130413 {GO:0004029=TAS, GO:0009055=TAS, GO:0044281=TAS, GO:0003842=EXP, GO:0042802=IPI, GO:0034641=TAS, GO:0019470=TAS, GO:0006560=TAS, GO:0005759=TAS, GO:0016620=IEA, GO:0010133=IEA, GO:0016491=IEA, GO:0006562=TAS, GO:0006561=IEA} 4-hydroxyproline catabolic process, cellular nitrogen compound metabolic process, proline biosynthetic process, proline catabolic process, proline catabolic process to glutamate, proline metabolic process, small molecule metabolic process mitochondrial matrix 1-pyrroline-5-carboxylate dehydrogenase activity, aldehyde dehydrogenase (NAD) activity, electron carrier activity, identical protein binding, oxidoreductase activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Human InterPro:IPR015590|InterPro:IPR016161|InterPro:IPR016162 ALDH5A1 HPA UniProtKB {GO:0009013=GO_REF:0000002, GO:0004777=PMID:7814412, GO:0006536=GO_REF:0000024, GO:0046459=GO_REF:0000024, GO:0007268=Reactome:REACT_13685, GO:0006749=GO_REF:0000024, GO:0006083=GO_REF:0000024, GO:0007417=PMID:9683595, GO:0007269=Reactome:REACT_13723, GO:0006681=GO_REF:0000024, GO:0042803=PMID:16199352, GO:0022904=GO_REF:0000024, GO:0005739=GO_REF:0000052, GO:0051289=PMID:16199352, GO:0006105=GO_REF:0000024, GO:0005759=Reactome:REACT_24017, GO:0006006=GO_REF:0000024, GO:0006650=GO_REF:0000024, GO:0009450=PMID:15037717, GO:0042135=GO_REF:0000024, GO:0006541=GO_REF:0000024} P51649 Succinate-semialdehyde dehydrogenase, mitochondrial protein 20111111 {GO:0009013=IEA, GO:0004777=ISS, GO:0006536=ISS, GO:0046459=ISS, GO:0007268=TAS, GO:0006749=ISS, GO:0006083=ISS, GO:0007417=IMP, GO:0007269=TAS, GO:0006681=ISS, GO:0042803=IC, GO:0022904=ISS, GO:0005739=IDA, GO:0051289=IDA, GO:0006105=ISS, GO:0005759=TAS, GO:0006006=ISS, GO:0006650=ISS, GO:0009450=IMP, GO:0042135=ISS, GO:0006541=ISS} acetate metabolic process, central nervous system development, galactosylceramide metabolic process, gamma-aminobutyric acid catabolic process, glucose metabolic process, glutamate metabolic process, glutamine metabolic process, glutathione metabolic process, glycerophospholipid metabolic process, neurotransmitter catabolic process, neurotransmitter secretion, protein homotetramerization, respiratory electron transport chain, short-chain fatty acid metabolic process, succinate metabolic process, synaptic transmission mitochondrial matrix, mitochondrion "protein homodimerization activity, succinate-semialdehyde dehydrogenase (NAD+) activity, succinate-semialdehyde dehydrogenase NAD(P)+"" activity""" Human ALDH6A1 HPA UniProtKB {GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0019859=GO_REF:0000024, GO:0009083=Reactome:REACT_197, GO:0044281=Reactome:REACT_111217, GO:0005739=GO_REF:0000052, GO:0034641=Reactome:REACT_13, GO:0050873=GO_REF:0000019, GO:0005759=Reactome:REACT_1077, GO:0018478=GO_REF:0000024, GO:0006573=GO_REF:0000024, GO:0004491=GO_REF:0000024, GO:0000062=GO_REF:0000024} Q02252 "Methylmalonate-semialdehyde dehydrogenase ""acylating"", mitochondrial" protein 20101115 {GO:0005730=IDA, GO:0005634=IDA, GO:0019859=ISS, GO:0009083=TAS, GO:0044281=TAS, GO:0005739=IDA, GO:0034641=TAS, GO:0050873=IEA, GO:0005759=TAS, GO:0018478=ISS, GO:0006573=ISS, GO:0004491=ISS, GO:0000062=ISS} branched-chain amino acid catabolic process, brown fat cell differentiation, cellular nitrogen compound metabolic process, small molecule metabolic process, thymine metabolic process, valine metabolic process mitochondrial matrix, mitochondrion, nucleolus, nucleus fatty-acyl-CoA binding, malonate-semialdehyde dehydrogenase (acetylating) activity, methylmalonate-semialdehyde dehydrogenase (acylating) activity Human ALDH7A1 HPA UniProtKB {GO:0005515=PMID:21988832, GO:0007605=PMID:9417906, GO:0019285=GO_REF:0000041, GO:0004029=GO_REF:0000024, GO:0006081=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0005829=GO_REF:0000039, GO:0005739=GO_REF:0000052, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000052, GO:0008802=GO_REF:0000003, GO:0005759=Reactome:REACT_1540, GO:0016620=GO_REF:0000002, GO:0016491=GO_REF:0000002, GO:0006554=Reactome:REACT_1298, GO:0004043=Reactome:REACT_1540} P49419 Alpha-aminoadipic semialdehyde dehydrogenase protein 20100326 {GO:0005515=IPI, GO:0007605=TAS, GO:0019285=IEA, GO:0004029=ISS, GO:0006081=ISS, GO:0005634=IEA, GO:0044281=TAS, GO:0005829=IEA, GO:0005739=IDA, GO:0034641=TAS, GO:0005737=IDA, GO:0008802=IEA, GO:0005759=TAS, GO:0016620=IEA, GO:0016491=IEA, GO:0006554=TAS, GO:0004043=EXP} cellular aldehyde metabolic process, cellular nitrogen compound metabolic process, glycine betaine biosynthetic process from choline, lysine catabolic process, sensory perception of sound, small molecule metabolic process cytoplasm, cytosol, mitochondrial matrix, mitochondrion, nucleus L-aminoadipate-semialdehyde dehydrogenase activity, aldehyde dehydrogenase (NAD) activity, betaine-aldehyde dehydrogenase activity, oxidoreductase activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, protein binding Human ALDH8A1 UniProtKB UniProtKB {GO:0005622=PMID:11007799, GO:0005737=GO_REF:0000039, GO:0001758=PMID:11007799, GO:0042574=PMID:11007799, GO:0042573=PMID:11007799, GO:0042904=GO_REF:0000019, GO:0016620=GO_REF:0000002} Q9H2A2 Aldehyde dehydrogenase family 8 member A1 protein 20031216 {GO:0005622=IDA, GO:0005737=IEA, GO:0001758=IDA, GO:0042574=IDA, GO:0042573=IDA, GO:0042904=IEA, GO:0016620=IEA} 9-cis-retinoic acid biosynthetic process, retinal metabolic process, retinoic acid metabolic process cytoplasm, intracellular oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, retinal dehydrogenase activity Human ALDH9A1 HPA UniProtKB {GO:0005886=GO_REF:0000052, GO:0006081=PMID:8645224, GO:0004029=PMID:2925663, GO:0004028=Reactome:REACT_220, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_220, GO:0005739=GO_REF:0000019, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000052, GO:0047105=GO_REF:0000003, GO:0016620=GO_REF:0000019, GO:0045329=Reactome:REACT_2125, GO:0019145=PMID:8645224, GO:0042445=PMID:2925663, GO:0033737=GO_REF:0000003, GO:0042136=PMID:2925663, GO:0009437=GO_REF:0000019, GO:0055114=PMID:2925663} P49189 4-trimethylaminobutyraldehyde dehydrogenase protein 20101115 {GO:0005886=IDA, GO:0006081=IDA, GO:0004029=IDA, GO:0004028=TAS, GO:0044281=TAS, GO:0005829=TAS, GO:0005739=IEA, GO:0034641=TAS, GO:0005737=IDA, GO:0047105=IEA, GO:0016620=IEA, GO:0045329=TAS, GO:0019145=IDA, GO:0042445=TAS, GO:0033737=IEA, GO:0042136=IDA, GO:0009437=IEA, GO:0055114=IDA} carnitine biosynthetic process, carnitine metabolic process, cellular aldehyde metabolic process, cellular nitrogen compound metabolic process, hormone metabolic process, neurotransmitter biosynthetic process, oxidation-reduction process, small molecule metabolic process cytoplasm, cytosol, mitochondrion, plasma membrane 1-pyrroline dehydrogenase activity, 3-chloroallyl aldehyde dehydrogenase activity, 4-trimethylammoniobutyraldehyde dehydrogenase activity, aldehyde dehydrogenase (NAD) activity, aminobutyraldehyde dehydrogenase activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Human ALDOA BHF-UCL UniProtKB {GO:0008092=PMID:9244396, GO:0008360=PMID:9244396, GO:0006094=Reactome:REACT_1520, GO:0006941=PMID:14615364, GO:0044281=Reactome:REACT_111217, GO:0015629=PMID:9244396, GO:0006096=PMID:14615364, GO:0046716=PMID:14615364, GO:0005829=Reactome:REACT_1602, GO:0042802=PMID:14766013, GO:0004332=PMID:9244396, GO:0006754=PMID:14615364, GO:0015631=PMID:17329259, GO:0051289=GO_REF:0000024, GO:0006006=Reactome:REACT_723, GO:0007015=PMID:1008835, GO:0031093=Reactome:REACT_21351, GO:0070061=PMID:14766013, GO:0006000=PMID:14615364, GO:0070062=PMID:17641064, GO:0005975=Reactome:REACT_474, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_21351, GO:0003779=PMID:1008835, GO:0030388=PMID:9244396, GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0031674=PMID:1008835} P04075 Fructose-bisphosphate aldolase A protein 20081006 {GO:0008092=IDA, GO:0008360=IDA, GO:0006094=TAS, GO:0006941=IMP, GO:0044281=TAS, GO:0015629=IDA, GO:0006096=IMP, GO:0046716=IMP, GO:0005829=TAS, GO:0042802=TAS, GO:0004332=IDA, GO:0006754=IMP, GO:0015631=TAS, GO:0051289=ISS, GO:0006006=TAS, GO:0007015=TAS, GO:0031093=TAS, GO:0070061=IDA, GO:0006000=IMP, GO:0070062=IDA, GO:0005975=TAS, GO:0030168=TAS, GO:0005576=TAS, GO:0003779=TAS, GO:0030388=IDA, GO:0007596=TAS, GO:0002576=TAS, GO:0031674=TAS} ATP biosynthetic process, actin filament organization, blood coagulation, carbohydrate metabolic process, fructose 1,6-bisphosphate metabolic process, fructose metabolic process, gluconeogenesis, glucose metabolic process, glycolysis, muscle cell homeostasis, platelet activation, platelet degranulation, protein homotetramerization, regulation of cell shape, small molecule metabolic process, striated muscle contraction I band, actin cytoskeleton, cytosol, extracellular region, extracellular vesicular exosome, platelet alpha granule lumen actin binding, cytoskeletal protein binding, fructose binding, fructose-bisphosphate aldolase activity, identical protein binding, tubulin binding Human ALDOB InterPro UniProtKB {GO:0008092=PMID:9244396, GO:0005515=PMID:18000879, GO:0070072=PMID:17576770, GO:0005815=PMID:18000879, GO:0005975=Reactome:REACT_474, GO:0034451=PMID:18000879, GO:0006094=Reactome:REACT_1520, GO:0044281=Reactome:REACT_111217, GO:0032781=PMID:17576770, GO:0006096=GO_REF:0000002, GO:0042802=PMID:10625657, GO:0005829=Reactome:REACT_2013, GO:0004332=GO_REF:0000002, GO:0030388=PMID:10625657, GO:0006116=PMID:17576770, GO:0051117=PMID:17576770, GO:0006006=Reactome:REACT_723, GO:0070061=PMID:10625657, GO:0006001=Reactome:REACT_1571, GO:0006000=PMID:3383242} Q5T7D5 Fructose-bisphosphate aldolase B protein 20130413 {GO:0008092=IDA, GO:0005515=IPI, GO:0070072=IGI, GO:0005815=IDA, GO:0005975=TAS, GO:0034451=IDA, GO:0006094=TAS, GO:0044281=TAS, GO:0032781=IGI, GO:0006096=IEA, GO:0042802=IPI, GO:0005829=TAS, GO:0004332=IEA, GO:0030388=IDA, GO:0006116=IDA, GO:0051117=IDA, GO:0006006=TAS, GO:0070061=IMP, GO:0006001=TAS, GO:0006000=IMP} NADH oxidation, carbohydrate metabolic process, fructose 1,6-bisphosphate metabolic process, fructose catabolic process, fructose metabolic process, gluconeogenesis, glucose metabolic process, glycolysis, positive regulation of ATPase activity, small molecule metabolic process, vacuolar proton-transporting V-type ATPase complex assembly centriolar satellite, cytosol, microtubule organizing center ATPase binding, cytoskeletal protein binding, fructose binding, fructose-bisphosphate aldolase activity, identical protein binding, protein binding Human InterPro:IPR000741 ALDOC BHF-UCL UniProtKB {GO:0008092=PMID:9244396, GO:0005515=PMID:11399750, GO:0001666=GO_REF:0000019, GO:0014070=GO_REF:0000019, GO:0030424=GO_REF:0000019, GO:0005975=Reactome:REACT_474, GO:0007568=GO_REF:0000019, GO:0031100=GO_REF:0000019, GO:0006094=Reactome:REACT_1520, GO:0006915=GO_REF:0000019, GO:0010243=GO_REF:0000019, GO:0051290=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0006096=Reactome:REACT_1383, GO:0005829=Reactome:REACT_1602, GO:0005739=GO_REF:0000019, GO:0004332=PMID:9244396, GO:0030388=PMID:9244396, GO:0051289=GO_REF:0000019, GO:0006006=Reactome:REACT_723, GO:0005856=PMID:9244396, GO:0006000=PMID:3105602} P09972 Fructose-bisphosphate aldolase C protein 20081007 {GO:0008092=IDA, GO:0005515=IPI, GO:0001666=IEA, GO:0014070=IEA, GO:0030424=IEA, GO:0005975=TAS, GO:0007568=IEA, GO:0031100=IEA, GO:0006094=TAS, GO:0006915=IEA, GO:0010243=IEA, GO:0051290=IEA, GO:0044281=TAS, GO:0006096=TAS, GO:0005829=TAS, GO:0005739=IEA, GO:0004332=IDA, GO:0030388=IDA, GO:0051289=IEA, GO:0006006=TAS, GO:0005856=IC, GO:0006000=TAS} aging, apoptotic process, carbohydrate metabolic process, fructose 1,6-bisphosphate metabolic process, fructose metabolic process, gluconeogenesis, glucose metabolic process, glycolysis, organ regeneration, protein heterotetramerization, protein homotetramerization, response to hypoxia, response to organic cyclic compound, response to organic nitrogen, small molecule metabolic process axon, cytoskeleton, cytosol, mitochondrion cytoskeletal protein binding, fructose-bisphosphate aldolase activity, protein binding Human ALG1 Reactome UniProtKB {GO:0000030=PMID:10704531, GO:0005783=PMID:10704531, GO:0016757=GO_REF:0000002, GO:0005789=Reactome:REACT_22214, GO:0004578=GO_REF:0000003, GO:0006486=PMID:10704531, GO:0016021=GO_REF:0000037, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0009103=PMID:10704531, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q9BT22 Chitobiosyldiphosphodolichol beta-mannosyltransferase protein 20130301 {GO:0000030=TAS, GO:0005783=TAS, GO:0016757=IEA, GO:0005789=TAS, GO:0004578=IEA, GO:0006486=TAS, GO:0016021=IEA, GO:0006488=TAS, GO:0044267=TAS, GO:0009103=TAS, GO:0043687=TAS, GO:0018279=TAS} cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, lipopolysaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine, protein glycosylation endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane chitobiosyldiphosphodolichol beta-mannosyltransferase activity, mannosyltransferase activity, transferase activity, transferring glycosyl groups Human ALG10 Reactome UniProtKB {GO:0016758=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q5BKT4 Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase protein 20130301 {GO:0016758=IEA, GO:0005789=IEA, GO:0016021=IEA, GO:0006488=TAS, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS} cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine endoplasmic reticulum membrane, integral to membrane transferase activity, transferring hexosyl groups Human ALG10B Reactome UniProtKB {GO:0005886=GO_REF:0000039, GO:0016758=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q5I7T1 Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase protein 20130301 {GO:0005886=IEA, GO:0016758=IEA, GO:0016021=IEA, GO:0006488=TAS, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS} cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine integral to membrane, plasma membrane transferase activity, transferring hexosyl groups Human ALG11 Reactome UniProtKB {GO:0005789=GO_REF:0000039, GO:0004377=GO_REF:0000003, GO:0016021=GO_REF:0000037, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q2TAA5 GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase protein 20130301 {GO:0005789=IEA, GO:0004377=IEA, GO:0016021=IEA, GO:0006488=TAS, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS} cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine endoplasmic reticulum membrane, integral to membrane GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity Human ALG12 Reactome UniProtKB {GO:0016757=GO_REF:0000002, GO:0005783=PMID:12217961, GO:0031227=GO_REF:0000002, GO:0006457=PMID:12217961, GO:0000009=PMID:12217961, GO:0005789=Reactome:REACT_22117, GO:0016021=GO_REF:0000037, GO:0006487=PMID:12217961, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0006506=GO_REF:0000002, GO:0018279=Reactome:REACT_22426, GO:0043687=Reactome:REACT_22161, GO:0052917=GO_REF:0000003} Q9BV10 Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase protein 20130301 {GO:0016757=IEA, GO:0005783=NAS, GO:0031227=IEA, GO:0006457=NAS, GO:0000009=IC, GO:0005789=TAS, GO:0016021=IEA, GO:0006487=IGI, GO:0006488=TAS, GO:0044267=TAS, GO:0006506=IEA, GO:0018279=TAS, GO:0043687=TAS, GO:0052917=IEA} GPI anchor biosynthetic process, cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation, protein N-linked glycosylation via asparagine, protein folding endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, intrinsic to endoplasmic reticulum membrane alpha-1,6-mannosyltransferase activity, dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity, transferase activity, transferring glycosyl groups Human ALG13 Reactome UniProtKB {GO:0004577=GO_REF:0000003, GO:0016758=GO_REF:0000002, GO:0005789=Reactome:REACT_22332, GO:0030246=GO_REF:0000002, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0030259=GO_REF:0000002, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q9NP73 UDP-N-acetylglucosamine transferase subunit ALG13 homolog protein 20130301 {GO:0004577=IEA, GO:0016758=IEA, GO:0005789=TAS, GO:0030246=IEA, GO:0006488=TAS, GO:0044267=TAS, GO:0030259=IEA, GO:0043687=TAS, GO:0018279=TAS} cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, lipid glycosylation, post-translational protein modification, protein N-linked glycosylation via asparagine endoplasmic reticulum membrane N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity, carbohydrate binding, transferase activity, transferring hexosyl groups Human ALG14 Reactome UniProtKB {GO:0005789=Reactome:REACT_22332, GO:0016021=GO_REF:0000037, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q96F25 UDP-N-acetylglucosamine transferase subunit ALG14 homolog protein 20130301 {GO:0005789=TAS, GO:0016021=IEA, GO:0006488=TAS, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS} cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine endoplasmic reticulum membrane, integral to membrane Human ALG1L UniProtKB UniProtKB {GO:0016757=GO_REF:0000037} Q6GMV1 Putative glycosyltransferase ALG1-like protein 20130413 {GO:0016757=IEA} transferase activity, transferring glycosyl groups Human UniProtKB-KW:KW-0328 ALG2 Reactome UniProtKB {GO:0005515=PMID:11883939, GO:0048471=PMID:17196169, GO:0000033=PMID:12684507, GO:0046982=PMID:11278427, GO:0033164=GO_REF:0000002, GO:0005634=PMID:17196169, GO:0004378=GO_REF:0000003, GO:0033577=PMID:12684507, GO:0051592=PMID:17196169, GO:0005737=PMID:17196169, GO:0047485=PMID:12445460, GO:0016020=PMID:16996505, GO:0005789=Reactome:REACT_22347, GO:0016021=GO_REF:0000037, GO:0006488=Reactome:REACT_22433, GO:0043495=PMID:16957052, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426, GO:0048306=PMID:14999017} Q9H553 Alpha-1,3/1,6-mannosyltransferase ALG2 protein 20130301 {GO:0005515=IPI, GO:0048471=IDA, GO:0000033=IDA, GO:0046982=IPI, GO:0033164=IEA, GO:0005634=IDA, GO:0004378=IEA, GO:0033577=IGI, GO:0051592=IDA, GO:0005737=IDA, GO:0047485=IPI, GO:0016020=IDA, GO:0005789=TAS, GO:0016021=IEA, GO:0006488=TAS, GO:0043495=IMP, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS, GO:0048306=IMP} cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine, protein glycosylation in endoplasmic reticulum, response to calcium ion cytoplasm, endoplasmic reticulum membrane, integral to membrane, membrane, nucleus, perinuclear region of cytoplasm GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity, alpha-1,3-mannosyltransferase activity, calcium-dependent protein binding, glycolipid 6-alpha-mannosyltransferase activity, protein N-terminus binding, protein anchor, protein binding, protein heterodimerization activity Human ALG3 Reactome UniProtKB {GO:0052925=GO_REF:0000003, GO:0000033=PMID:10581255, GO:0016758=GO_REF:0000002, GO:0005783=GO_REF:0000002, GO:0005789=Reactome:REACT_22415, GO:0006486=PMID:10581255, GO:0016021=GO_REF:0000037, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q92685 Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase protein 20130301 {GO:0052925=IEA, GO:0000033=IDA, GO:0016758=IEA, GO:0005783=IEA, GO:0005789=TAS, GO:0006486=NAS, GO:0016021=IEA, GO:0006488=TAS, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS} cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine, protein glycosylation endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane alpha-1,3-mannosyltransferase activity, dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity, transferase activity, transferring hexosyl groups Human ALG5 Reactome UniProtKB {GO:0004576=PMID:10359825, GO:0004581=GO_REF:0000003, GO:0007368=GO_REF:0000019, GO:0016757=GO_REF:0000038, GO:0005789=Reactome:REACT_22143, GO:0006486=PMID:10359825, GO:0016021=GO_REF:0000037, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q9Y673 Dolichyl-phosphate beta-glucosyltransferase protein 20130301 {GO:0004576=TAS, GO:0004581=IEA, GO:0007368=IEA, GO:0016757=IEA, GO:0005789=TAS, GO:0006486=TAS, GO:0016021=IEA, GO:0006488=TAS, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS} cellular protein metabolic process, determination of left/right symmetry, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine, protein glycosylation endoplasmic reticulum membrane, integral to membrane dolichyl-phosphate beta-glucosyltransferase activity, oligosaccharyl transferase activity, transferase activity, transferring glycosyl groups Human ALG8 Reactome UniProtKB {GO:0000033=PMID:12480927, GO:0016758=GO_REF:0000002, GO:0005789=Reactome:REACT_22158, GO:0006487=PMID:12480927, GO:0016021=GO_REF:0000037, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q9BVK2 Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase protein 20130301 {GO:0000033=IMP, GO:0016758=IEA, GO:0005789=TAS, GO:0006487=IMP, GO:0016021=IEA, GO:0006488=TAS, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS} cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation, protein N-linked glycosylation via asparagine endoplasmic reticulum membrane, integral to membrane alpha-1,3-mannosyltransferase activity, transferase activity, transferring hexosyl groups Human ALG9 Reactome UniProtKB {GO:0052926=GO_REF:0000003, GO:0016757=GO_REF:0000002, GO:0005789=Reactome:REACT_22307, GO:0031227=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0052918=GO_REF:0000003, GO:0006506=GO_REF:0000002, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q9H6U8 Alpha-1,2-mannosyltransferase ALG9 protein 20130301 {GO:0052926=IEA, GO:0016757=IEA, GO:0005789=TAS, GO:0031227=IEA, GO:0016021=IEA, GO:0006488=TAS, GO:0044267=TAS, GO:0052918=IEA, GO:0006506=IEA, GO:0043687=TAS, GO:0018279=TAS} GPI anchor biosynthetic process, cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine endoplasmic reticulum membrane, integral to membrane, intrinsic to endoplasmic reticulum membrane dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity, dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity, transferase activity, transferring glycosyl groups Human ALK GOC UniProtKB {GO:0005515=PMID:22939624, GO:0008283=PMID:19459784, GO:0042981=PMID:19459784, GO:0005524=GO_REF:0000037, GO:0038061=PMID:19459784, GO:0000187=PMID:19459784, GO:0016310=PMID:19459784, GO:0007165=PMID:19459784, GO:0004704=PMID:19459784, GO:0046777=PMID:19459784, GO:0051092=PMID:19459784, GO:0048666=PMID:19459784, GO:0005887=PMID:19459784, GO:0004714=PMID:19459784, GO:0007169=GO_REF:0000002} Q9UM73 ALK tyrosine kinase receptor protein 20130413 {GO:0005515=IPI, GO:0008283=TAS, GO:0042981=TAS, GO:0005524=IEA, GO:0038061=TAS, GO:0000187=TAS, GO:0016310=TAS, GO:0007165=TAS, GO:0004704=TAS, GO:0046777=TAS, GO:0051092=TAS, GO:0048666=TAS, GO:0005887=TAS, GO:0004714=TAS, GO:0007169=IEA} NIK/NF-kappaB cascade, activation of MAPK activity, cell proliferation, neuron development, phosphorylation, positive regulation of NF-kappaB transcription factor activity, protein autophosphorylation, regulation of apoptotic process, signal transduction, transmembrane receptor protein tyrosine kinase signaling pathway integral to plasma membrane ATP binding, NF-kappaB-inducing kinase activity, protein binding, transmembrane receptor protein tyrosine kinase activity Human ALKBH1 UniProtKB UniProtKB {GO:0003906=PMID:19959401, GO:0005719=GO_REF:0000019, GO:0070989=PMID:18603530, GO:0042245=PMID:18603530, GO:0001890=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0042056=GO_REF:0000019, GO:0031175=GO_REF:0000019, GO:0008198=PMID:18603530, GO:0005739=PMID:18603530, GO:0043524=GO_REF:0000019, GO:0006307=PMID:18603530, GO:0006281=PMID:19959401, GO:0048589=GO_REF:0000019, GO:0080111=PMID:18603530, GO:0070579=PMID:18603530, GO:0016702=GO_REF:0000037, GO:0001764=GO_REF:0000019} Q13686 Alkylated DNA repair protein alkB homolog 1 protein 20100429 {GO:0003906=IDA, GO:0005719=IEA, GO:0070989=IDA, GO:0042245=IDA, GO:0001890=IEA, GO:0001701=IEA, GO:0042056=IEA, GO:0031175=IEA, GO:0008198=IDA, GO:0005739=IDA, GO:0043524=IEA, GO:0006307=IDA, GO:0006281=IDA, GO:0048589=IEA, GO:0080111=IDA, GO:0070579=IDA, GO:0016702=IEA, GO:0001764=IEA} DNA dealkylation involved in DNA repair, DNA demethylation, DNA repair, RNA repair, developmental growth, in utero embryonic development, negative regulation of neuron apoptotic process, neuron migration, neuron projection development, oxidative demethylation, placenta development mitochondrion, nuclear euchromatin DNA-(apurinic or apyrimidinic site) lyase activity, chemoattractant activity, ferrous iron binding, methylcytosine dioxygenase activity, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Human ALKBH2 BHF-UCL UniProtKB {GO:0006281=Reactome:REACT_216, GO:0006307=PMID:18775698, GO:0070989=PMID:18775698, GO:0080111=PMID:18775698, GO:0035511=PMID:18432238, GO:0043734=PMID:18432238, GO:0016706=GO_REF:0000019, GO:0005654=Reactome:REACT_2185, GO:0016702=GO_REF:0000037, GO:0051747=PMID:18775698, GO:0008198=PMID:18432238} Q6NS38 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2 protein 20100115 {GO:0006281=TAS, GO:0006307=TAS, GO:0070989=TAS, GO:0080111=TAS, GO:0035511=IDA, GO:0043734=IDA, GO:0016706=IEA, GO:0005654=TAS, GO:0016702=IEA, GO:0051747=TAS, GO:0008198=IDA} DNA dealkylation involved in DNA repair, DNA demethylation, DNA repair, oxidative DNA demethylation, oxidative demethylation nucleoplasm DNA-N1-methyladenine dioxygenase activity, cytosine C-5 DNA demethylase activity, ferrous iron binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Human ALKBH3 HPA UniProtKB {GO:0005515=PMID:22055184, GO:0031418=GO_REF:0000037, GO:0008283=PMID:22055184, GO:0043734=PMID:22055184, GO:0005634=GO_REF:0000052, GO:0008198=PMID:16858410, GO:0035552=PMID:22055184, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0006307=Reactome:REACT_2020, GO:0006281=Reactome:REACT_216, GO:0016706=GO_REF:0000002, GO:0005654=Reactome:REACT_1934, GO:0016702=GO_REF:0000037, GO:0051747=GO_REF:0000019} Q96Q83 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 protein 20101115 {GO:0005515=IPI, GO:0031418=IEA, GO:0008283=IMP, GO:0043734=IMP, GO:0005634=IDA, GO:0008198=IDA, GO:0035552=IMP, GO:0005739=IDA, GO:0005737=IDA, GO:0006307=TAS, GO:0006281=TAS, GO:0016706=IEA, GO:0005654=TAS, GO:0016702=IEA, GO:0051747=IEA} DNA dealkylation involved in DNA repair, DNA repair, cell proliferation, oxidative single-stranded DNA demethylation cytoplasm, mitochondrion, nucleoplasm, nucleus DNA-N1-methyladenine dioxygenase activity, L-ascorbic acid binding, cytosine C-5 DNA demethylase activity, ferrous iron binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, protein binding Human ALKBH5 UniProtKB UniProtKB {GO:0006397=PMID:23177736, GO:0001666=PMID:21264265, GO:0006406=PMID:23177736, GO:0016607=PMID:23177736, GO:0016706=PMID:21264265, GO:0005634=PMID:21264265, GO:0007283=GO_REF:0000024, GO:0035515=PMID:23177736, GO:0016702=GO_REF:0000037, GO:0035553=PMID:23177736, GO:0046872=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q6P6C2 RNA demethylase ALKBH5 protein 20130118 {GO:0006397=IMP, GO:0001666=IDA, GO:0006406=IMP, GO:0016607=IDA, GO:0016706=IDA, GO:0005634=IDA, GO:0007283=ISS, GO:0035515=IDA, GO:0016702=IEA, GO:0035553=IDA, GO:0046872=IEA, GO:0030154=IEA} cell differentiation, mRNA export from nucleus, mRNA processing, oxidative single-stranded RNA demethylation, response to hypoxia, spermatogenesis nuclear speck, nucleus metal ion binding, oxidative RNA demethylase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Human UniProtKB:Q3TSG4 ALKBH7 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0005576=GO_REF:0000039, GO:0016702=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q9BT30 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7 protein 20130413 {GO:0005739=IEA, GO:0005634=IEA, GO:0005576=IEA, GO:0016702=IEA, GO:0046872=IEA} extracellular region, mitochondrion, nucleus metal ion binding, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Human UniProtKB-SubCell:SL-0191 ALMS1 HPA UniProtKB {GO:0001736=GO_REF:0000019, GO:0019722=GO_REF:0000019, GO:0060122=GO_REF:0000019, GO:0045598=GO_REF:0000019, GO:0007605=GO_REF:0000019, GO:0051492=PMID:22693585, GO:0007286=GO_REF:0000019, GO:0005829=Reactome:REACT_15470, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0048589=GO_REF:0000019, GO:0040015=GO_REF:0000019, GO:0000086=Reactome:REACT_2203, GO:0016197=PMID:22693585, GO:0045444=GO_REF:0000019, GO:0005932=GO_REF:0000039, GO:0042632=GO_REF:0000019, GO:0005813=PMID:15855349, GO:0005814=PMID:20844083, GO:0046548=GO_REF:0000019, GO:0006915=GO_REF:0000019, GO:0042593=GO_REF:0000019, GO:0050673=GO_REF:0000019, GO:0008150=GO_REF:0000015, GO:0005929=GO_REF:0000037, GO:0042384=GO_REF:0000019, GO:0000922=GO_REF:0000039, GO:0006641=GO_REF:0000019, GO:0000278=Reactome:REACT_152, GO:0030728=GO_REF:0000019} Q8TCU4 Alstrom syndrome protein 1 protein 20111111 {GO:0001736=IEA, GO:0019722=IEA, GO:0060122=IEA, GO:0045598=IEA, GO:0007605=IEA, GO:0051492=IMP, GO:0007286=IEA, GO:0005829=TAS, GO:0003674=ND, GO:0005737=IDA, GO:0048589=IEA, GO:0040015=IEA, GO:0000086=TAS, GO:0016197=IMP, GO:0045444=IEA, GO:0005932=IEA, GO:0042632=IEA, GO:0005813=IDA, GO:0005814=IDA, GO:0046548=IEA, GO:0006915=IEA, GO:0042593=IEA, GO:0050673=IEA, GO:0008150=ND, GO:0005929=IEA, GO:0042384=IEA, GO:0000922=IEA, GO:0006641=IEA, GO:0000278=TAS, GO:0030728=IEA} G2/M transition of mitotic cell cycle, apoptotic process, biological_process, calcium-mediated signaling, cholesterol homeostasis, cilium assembly, developmental growth, endosomal transport, epithelial cell proliferation, establishment of planar polarity, fat cell differentiation, glucose homeostasis, inner ear receptor stereocilium organization, mitotic cell cycle, negative regulation of multicellular organism growth, ovulation, regulation of fat cell differentiation, regulation of stress fiber assembly, retinal rod cell development, sensory perception of sound, spermatid development, triglyceride metabolic process centriole, centrosome, cilium, cytoplasm, cytosol, microtubule basal body, spindle pole molecular_function Human ALOX12 Reactome UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0008284=GO_REF:0000024, GO:0030307=PMID:14767568, GO:0006928=PMID:14669797, GO:0044281=Reactome:REACT_111217, GO:0006691=GO_REF:0000002, GO:0005829=Reactome:REACT_150433, GO:0071396=GO_REF:0000019, GO:0051901=GO_REF:0000019, GO:0045909=GO_REF:0000019, GO:2001300=Reactome:REACT_150320, GO:0042554=PMID:15107407, GO:0019370=GO_REF:0000037, GO:0043066=GO_REF:0000024, GO:0019395=PMID:15111312, GO:0043065=GO_REF:0000019, GO:0005506=GO_REF:0000002, GO:0019372=Reactome:REACT_150201, GO:0007568=GO_REF:0000019, GO:0072593=PMID:12858336, GO:0048661=GO_REF:0000019, GO:0045785=PMID:14669797, GO:0043280=GO_REF:0000019, GO:0010628=GO_REF:0000019, GO:0010595=GO_REF:0000019, GO:0042383=PMID:15107407, GO:0004052=Reactome:REACT_150327, GO:0016165=GO_REF:0000002, GO:0047977=GO_REF:0000024, GO:0016702=Reactome:REACT_150303, GO:0051121=Reactome:REACT_150292, GO:0045603=GO_REF:0000019, GO:0051120=Reactome:REACT_150129} P18054 Arachidonate 12-lipoxygenase, 12S-type protein 20120224 {GO:0019369=TAS, GO:0008284=ISS, GO:0030307=IMP, GO:0006928=IMP, GO:0044281=TAS, GO:0006691=IEA, GO:0005829=TAS, GO:0071396=IEA, GO:0051901=IEA, GO:0045909=IEA, GO:2001300=TAS, GO:0042554=NAS, GO:0019370=IEA, GO:0043066=ISS, GO:0019395=IMP, GO:0043065=IEA, GO:0005506=IEA, GO:0019372=TAS, GO:0007568=IEA, GO:0072593=NAS, GO:0048661=IEA, GO:0045785=IMP, GO:0043280=IEA, GO:0010628=IEA, GO:0010595=IEA, GO:0042383=IDA, GO:0004052=TAS, GO:0016165=IEA, GO:0047977=ISS, GO:0016702=TAS, GO:0051121=TAS, GO:0045603=IEA, GO:0051120=TAS} aging, arachidonic acid metabolic process, cellular component movement, cellular response to lipid, fatty acid oxidation, hepoxilin metabolic process, leukotriene biosynthetic process, leukotriene metabolic process, lipoxin metabolic process, lipoxygenase pathway, negative regulation of apoptotic process, positive regulation of apoptotic process, positive regulation of cell adhesion, positive regulation of cell growth, positive regulation of cell proliferation, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of endothelial cell differentiation, positive regulation of endothelial cell migration, positive regulation of gene expression, positive regulation of mitochondrial depolarization, positive regulation of smooth muscle cell proliferation, positive regulation of vasodilation, reactive oxygen species metabolic process, small molecule metabolic process, superoxide anion generation cytosol, sarcolemma arachidonate 12-lipoxygenase activity, hepoxilin A3 synthase activity, hepoxilin-epoxide hydrolase activity, iron ion binding, lipoxygenase activity, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Human ALOX12B Reactome UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0006629=PMID:9618483, GO:0019370=GO_REF:0000037, GO:0004052=Reactome:REACT_150226, GO:0008544=PMID:9618483, GO:0005506=GO_REF:0000002, GO:0016165=GO_REF:0000002, GO:0019372=Reactome:REACT_150201, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_150226} O75342 Arachidonate 12-lipoxygenase, 12R-type protein 20120224 {GO:0019369=TAS, GO:0006629=TAS, GO:0019370=IEA, GO:0004052=TAS, GO:0008544=TAS, GO:0005506=IEA, GO:0016165=IEA, GO:0019372=TAS, GO:0044281=TAS, GO:0005829=TAS} arachidonic acid metabolic process, epidermis development, leukotriene biosynthetic process, lipid metabolic process, lipoxygenase pathway, small molecule metabolic process cytosol arachidonate 12-lipoxygenase activity, iron ion binding, lipoxygenase activity Human ALOX15B Reactome UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0006629=PMID:11839751, GO:0019370=GO_REF:0000037, GO:0030336=PMID:11839751, GO:0008285=PMID:11839751, GO:0005506=GO_REF:0000002, GO:0019372=Reactome:REACT_150422, GO:0044281=Reactome:REACT_111217, GO:0006917=PMID:11839751, GO:0045786=PMID:11839751, GO:0006691=GO_REF:0000002, GO:0005829=Reactome:REACT_150130, GO:0005622=PMID:11839751, GO:0030856=PMID:11839751, GO:0016165=GO_REF:0000002, GO:0006631=PMID:9177185, GO:0030850=PMID:11839751, GO:0045926=PMID:11839751, GO:0050473=PMID:11839751} O15296 Arachidonate 15-lipoxygenase B protein 20120224 {GO:0019369=TAS, GO:0006629=TAS, GO:0019370=IEA, GO:0030336=TAS, GO:0008285=IDA, GO:0005506=IEA, GO:0019372=TAS, GO:0044281=TAS, GO:0006917=TAS, GO:0045786=IDA, GO:0006691=IEA, GO:0005829=TAS, GO:0005622=IDA, GO:0030856=NAS, GO:0016165=IEA, GO:0006631=TAS, GO:0030850=NAS, GO:0045926=IDA, GO:0050473=IDA} arachidonic acid metabolic process, fatty acid metabolic process, induction of apoptosis, leukotriene biosynthetic process, leukotriene metabolic process, lipid metabolic process, lipoxygenase pathway, negative regulation of cell cycle, negative regulation of cell migration, negative regulation of cell proliferation, negative regulation of growth, prostate gland development, regulation of epithelial cell differentiation, small molecule metabolic process cytosol, intracellular arachidonate 15-lipoxygenase activity, iron ion binding, lipoxygenase activity Human ALOX5 IntAct UniProtKB {GO:0005515=PMID:11297527, GO:0019369=Reactome:REACT_147851, GO:0019370=PMID:21233389, GO:0031965=PMID:8245774, GO:0005506=PMID:21233389, GO:0019372=Reactome:REACT_150209, GO:0044281=Reactome:REACT_111217, GO:0005635=Reactome:REACT_150273, GO:0006691=Reactome:REACT_150420, GO:0016363=PMID:19233132, GO:0005829=Reactome:REACT_22105, GO:0004051=PMID:21233389, GO:0002540=GO_REF:0000019, GO:0016165=GO_REF:0000002, GO:0005641=PMID:8245774, GO:2001300=Reactome:REACT_150320} P09917 Arachidonate 5-lipoxygenase protein 20130415 {GO:0005515=IPI, GO:0019369=TAS, GO:0019370=IDA, GO:0031965=IDA, GO:0005506=IDA, GO:0019372=TAS, GO:0044281=TAS, GO:0005635=TAS, GO:0006691=TAS, GO:0016363=IDA, GO:0005829=TAS, GO:0004051=IDA, GO:0002540=IEA, GO:0016165=IEA, GO:0005641=IDA, GO:2001300=TAS} arachidonic acid metabolic process, leukotriene biosynthetic process, leukotriene metabolic process, leukotriene production involved in inflammatory response, lipoxin metabolic process, lipoxygenase pathway, small molecule metabolic process cytosol, nuclear envelope, nuclear envelope lumen, nuclear matrix, nuclear membrane arachidonate 5-lipoxygenase activity, iron ion binding, lipoxygenase activity, protein binding Human UniProtKB:Q14019 ALOX5AP Reactome UniProtKB {GO:0005515=PMID:19233132, GO:0019369=Reactome:REACT_147851, GO:0050544=PMID:8440384, GO:0005783=PMID:19233132, GO:0044281=Reactome:REACT_111217, GO:0005635=Reactome:REACT_150273, GO:0006691=Reactome:REACT_150420, GO:0042803=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0004602=GO_REF:0000033, GO:0070207=PMID:17600184, GO:0002675=GO_REF:0000019, GO:0002540=GO_REF:0000019, GO:0006750=GO_REF:0000033, GO:0071277=PMID:2300173, GO:2001300=Reactome:REACT_150320, GO:0019370=PMID:2300173, GO:0031965=PMID:8245774, GO:0046982=GO_REF:0000019, GO:0019372=Reactome:REACT_150209, GO:0004464=GO_REF:0000033, GO:0004364=GO_REF:0000033, GO:0004051=GO_REF:0000033, GO:0047485=PMID:19233132, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0019899=GO_REF:0000019, GO:0008047=GO_REF:0000002} P20292 Arachidonate 5-lipoxygenase-activating protein protein 20130213 {GO:0005515=IPI, GO:0019369=TAS, GO:0050544=IDA, GO:0005783=IDA, GO:0044281=TAS, GO:0005635=TAS, GO:0006691=TAS, GO:0042803=IEA, GO:0005829=IEA, GO:0004602=IBA, GO:0070207=IPI, GO:0002675=IEA, GO:0002540=IEA, GO:0006750=IBA, GO:0071277=IDA, GO:2001300=TAS, GO:0019370=IDA, GO:0031965=IDA, GO:0046982=IEA, GO:0019372=TAS, GO:0004464=IBA, GO:0004364=IBA, GO:0004051=IBA, GO:0047485=IPI, GO:0005789=IEA, GO:0016021=IEA, GO:0019899=IEA, GO:0008047=IEA} arachidonic acid metabolic process, cellular response to calcium ion, glutathione biosynthetic process, leukotriene biosynthetic process, leukotriene metabolic process, leukotriene production involved in inflammatory response, lipoxin metabolic process, lipoxygenase pathway, positive regulation of acute inflammatory response, protein homotrimerization, small molecule metabolic process cytosol, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, nuclear envelope, nuclear membrane arachidonate 5-lipoxygenase activity, arachidonic acid binding, enzyme activator activity, enzyme binding, glutathione peroxidase activity, glutathione transferase activity, leukotriene-C4 synthase activity, protein N-terminus binding, protein binding, protein heterodimerization activity, protein homodimerization activity Human ALOXE3 UniProtKB UniProtKB {GO:0019370=GO_REF:0000037, GO:0005506=GO_REF:0000002, GO:0016165=GO_REF:0000002, GO:0016702=GO_REF:0000038, GO:0046872=GO_REF:0000038} Q9BYJ1 Epidermis-type lipoxygenase 3 protein 20130413 {GO:0019370=IEA, GO:0005506=IEA, GO:0016165=IEA, GO:0016702=IEA, GO:0046872=IEA} leukotriene biosynthetic process iron ion binding, lipoxygenase activity, metal ion binding, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Human UniProtKB-KW:KW-0434 ALPI UniProtKB UniProtKB {GO:0016310=GO_REF:0000029, GO:0016020=GO_REF:0000029, GO:0004035=PMID:2841341, GO:0005886=GO_REF:0000039, GO:0031225=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0046872=GO_REF:0000037} P09923 Intestinal-type alkaline phosphatase protein 20021104 {GO:0016310=NAS, GO:0016020=NAS, GO:0004035=NAS, GO:0005886=IEA, GO:0031225=IEA, GO:0016021=IEA, GO:0046872=IEA} phosphorylation anchored to membrane, integral to membrane, membrane, plasma membrane alkaline phosphatase activity, metal ion binding Human ALPK1 UniProtKB UniProtKB {GO:0004674=GO_REF:0000037, GO:0016301=GO_REF:0000038, GO:0005524=GO_REF:0000002} Q96QP1 Alpha-protein kinase 1 protein 20130413 {GO:0004674=IEA, GO:0016301=IEA, GO:0005524=IEA} ATP binding, kinase activity, protein serine/threonine kinase activity Human UniProtKB-KW:KW-0723 ALPK2 UniProtKB UniProtKB {GO:0004674=GO_REF:0000037, GO:0005524=GO_REF:0000002} Q86TB3 Alpha-protein kinase 2 protein 20130413 {GO:0004674=IEA, GO:0005524=IEA} ATP binding, protein serine/threonine kinase activity Human UniProtKB-KW:KW-0723 ALPL BHF-UCL UniProtKB {GO:0005886=GO_REF:0000039, GO:0071529=GO_REF:0000019, GO:0033280=PMID:17023519, GO:0051384=GO_REF:0000019, GO:0031225=GO_REF:0000037, GO:0005615=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0003006=GO_REF:0000019, GO:0001501=PMID:9781036, GO:0001958=GO_REF:0000019, GO:0016462=PMID:19874193, GO:0071407=GO_REF:0000019, GO:0004035=GO_REF:0000003, GO:0032496=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0044420=GO_REF:0000019, GO:0046677=GO_REF:0000019} P05186 Alkaline phosphatase, tissue-nonspecific isozyme protein 20090507 {GO:0005886=IEA, GO:0071529=IEA, GO:0033280=IEP, GO:0051384=IEA, GO:0031225=IEA, GO:0005615=IEA, GO:0046872=IEA, GO:0003006=IEA, GO:0001501=TAS, GO:0001958=IEA, GO:0016462=IDA, GO:0071407=IEA, GO:0004035=IEA, GO:0032496=IEA, GO:0016021=IEA, GO:0044420=IEA, GO:0046677=IEA} cellular response to organic cyclic compound, cementum mineralization, developmental process involved in reproduction, endochondral ossification, response to antibiotic, response to glucocorticoid stimulus, response to lipopolysaccharide, response to vitamin D, skeletal system development anchored to membrane, extracellular matrix part, extracellular space, integral to membrane, plasma membrane alkaline phosphatase activity, metal ion binding, pyrophosphatase activity Human ALPP MGI UniProtKB {GO:0004035=PMID:2133555, GO:0009986=PMID:12493773, GO:0005886=GO_REF:0000039, GO:0031225=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0046872=GO_REF:0000037} P05187 Alkaline phosphatase, placental type protein 20100113 {GO:0004035=IDA, GO:0009986=IDA, GO:0005886=IEA, GO:0031225=IEA, GO:0016021=IEA, GO:0046872=IEA} anchored to membrane, cell surface, integral to membrane, plasma membrane alkaline phosphatase activity, metal ion binding Human ALPPL2 UniProtKB UniProtKB {GO:0016310=GO_REF:0000029, GO:0016020=GO_REF:0000029, GO:0004035=PMID:2162249, GO:0005886=GO_REF:0000039, GO:0031225=GO_REF:0000037, GO:0046872=GO_REF:0000037} P10696 Alkaline phosphatase, placental-like protein 20021104 {GO:0016310=NAS, GO:0016020=NAS, GO:0004035=NAS, GO:0005886=IEA, GO:0031225=IEA, GO:0046872=IEA} phosphorylation anchored to membrane, membrane, plasma membrane alkaline phosphatase activity, metal ion binding Human ALS2 GOC UniProtKB {GO:0008219=GO_REF:0000019, GO:0030424=GO_REF:0000019, GO:0071902=PMID:16049005, GO:0035022=PMID:16049005, GO:0035023=GO_REF:0000002, GO:0007409=GO_REF:0000019, GO:0032855=PMID:16049005, GO:0042803=PMID:15247254, GO:0030425=PMID:15371724, GO:0005829=PMID:12837691, GO:0043231=GO_REF:0000019, GO:0030426=GO_REF:0000024, GO:0005085=PMID:15247254, GO:0005622=GO_REF:0000002, GO:0016050=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0032313=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0008104=GO_REF:0000019, GO:0051036=PMID:15247254, GO:0001881=GO_REF:0000019, GO:0007528=GO_REF:0000019, GO:0045860=PMID:16049005, GO:0016197=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0001662=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0007032=PMID:17239822, GO:0005089=GO_REF:0000002, GO:0006979=GO_REF:0000019, GO:0030676=PMID:16049005, GO:0005087=PMID:11586298, GO:0017112=PMID:12837691, GO:0017137=PMID:16670179, GO:0005813=PMID:16085057, GO:0035249=GO_REF:0000019, GO:0014069=GO_REF:0000019, GO:0031982=PMID:12837691, GO:0001726=GO_REF:0000024, GO:0001701=GO_REF:0000019, GO:0030027=GO_REF:0000024, GO:0043234=PMID:15247254, GO:0016601=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0048812=PMID:16049005, GO:0043539=PMID:16049005, GO:0005769=PMID:12837691} Q96Q42 Alsin protein 20130413 {GO:0008219=IEA, GO:0030424=IEA, GO:0071902=IDA, GO:0035022=IC, GO:0035023=IEA, GO:0007409=IEA, GO:0032855=IDA, GO:0042803=IPI, GO:0030425=IDA, GO:0005829=IDA, GO:0043231=IEA, GO:0030426=ISS, GO:0005085=IDA, GO:0005622=IEA, GO:0016050=IEA, GO:0005737=IEA, GO:0032313=IEA, GO:0005543=IEA, GO:0008104=IEA, GO:0051036=IEP, GO:0001881=IEA, GO:0007528=IEA, GO:0045860=IDA, GO:0016197=IEA, GO:0043025=IEA, GO:0001662=IEA, GO:0007626=IEA, GO:0007032=IGI, GO:0005089=IEA, GO:0006979=IEA, GO:0030676=IDA, GO:0005087=NAS, GO:0017112=IDA, GO:0017137=NAS, GO:0005813=IDA, GO:0035249=IEA, GO:0014069=IEA, GO:0031982=IDA, GO:0001726=ISS, GO:0001701=IEA, GO:0030027=ISS, GO:0043234=IDA, GO:0016601=IEA, GO:0016020=IEA, GO:0048812=IDA, GO:0043539=IDA, GO:0005769=IDA} Rac protein signal transduction, axonogenesis, behavioral fear response, cell death, endosomal transport, endosome organization, in utero embryonic development, locomotory behavior, neuromuscular junction development, neuron projection morphogenesis, positive regulation of Rac GTPase activity, positive regulation of Rac protein signal transduction, positive regulation of protein kinase activity, positive regulation of protein serine/threonine kinase activity, protein localization, receptor recycling, regulation of Rab GTPase activity, regulation of Rho protein signal transduction, regulation of endosome size, response to oxidative stress, synaptic transmission, glutamatergic, vesicle organization axon, centrosome, cytoplasm, cytosol, dendrite, early endosome, growth cone, intracellular, intracellular membrane-bounded organelle, lamellipodium, membrane, neuronal cell body, postsynaptic density, protein complex, ruffle, vesicle Rab GTPase binding, Rab guanyl-nucleotide exchange factor activity, Rac guanyl-nucleotide exchange factor activity, Ran guanyl-nucleotide exchange factor activity, Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, phospholipid binding, protein homodimerization activity, protein serine/threonine kinase activator activity Human ALS2CL MGI UniProtKB {GO:0005622=GO_REF:0000002, GO:0017137=GO_REF:0000019, GO:0008104=GO_REF:0000019, GO:0035023=GO_REF:0000002, GO:0016023=GO_REF:0000019, GO:0007032=PMID:17239822, GO:0005089=GO_REF:0000002, GO:0042802=PMID:17239822, GO:0005096=GO_REF:0000037} Q60I27 ALS2 C-terminal-like protein protein 20070418 {GO:0005622=IEA, GO:0017137=IEA, GO:0008104=IEA, GO:0035023=IEA, GO:0016023=IEA, GO:0007032=IGI, GO:0005089=IEA, GO:0042802=IPI, GO:0005096=IEA} endosome organization, protein localization, regulation of Rho protein signal transduction cytoplasmic membrane-bounded vesicle, intracellular GTPase activator activity, Rab GTPase binding, Rho guanyl-nucleotide exchange factor activity, identical protein binding Human UniProtKB:Q60I27 ALS2CR11 null null {} null null null null {} null null null ALS2CR12 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0043087=PMID:11586298} Q96Q35 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein protein 20130415 {GO:0005515=IPI, GO:0003674=ND, GO:0005737=IEA, GO:0005575=ND, GO:0043087=NAS} regulation of GTPase activity cellular_component, cytoplasm molecular_function, protein binding Human UniProtKB:O00204 ALS2CR8 ENSEMBL UniProtKB {GO:0003700=GO_REF:0000019, GO:0005730=GO_REF:0000019, GO:0005654=GO_REF:0000019} Q8N187 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein protein 20130413 {GO:0003700=IEA, GO:0005730=IEA, GO:0005654=IEA} nucleolus, nucleoplasm sequence-specific DNA binding transcription factor activity Human Ensembl:ENSMUSP00000027171 ALX1 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0005667=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0006366=PMID:8756334, GO:0046982=GO_REF:0000019, GO:0003714=PMID:8756334, GO:0001843=GO_REF:0000019, GO:0007275=PMID:8756334, GO:0048704=GO_REF:0000019, GO:0005634=PMID:9753625, GO:0000122=PMID:8756334, GO:0030326=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0007420=PMID:8673125, GO:0001502=PMID:8756334, GO:0045944=GO_REF:0000019, GO:0014031=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:0045893=PMID:9753625} Q15699 ALX homeobox protein 1 protein 20130415 {GO:0005515=IPI, GO:0005667=IEA, GO:0003700=IEA, GO:0006366=TAS, GO:0046982=IEA, GO:0003714=TAS, GO:0001843=IEA, GO:0007275=TAS, GO:0048704=IEA, GO:0005634=IDA, GO:0000122=IDA, GO:0030326=IEA, GO:0009952=IEA, GO:0043565=IEA, GO:0007420=TAS, GO:0001502=TAS, GO:0045944=IEA, GO:0014031=IEA, GO:0060021=IEA, GO:0045893=IDA} anterior/posterior pattern specification, brain development, cartilage condensation, embryonic limb morphogenesis, embryonic skeletal system morphogenesis, mesenchymal cell development, multicellular organismal development, negative regulation of transcription from RNA polymerase II promoter, neural tube closure, palate development, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter nucleus, transcription factor complex protein binding, protein heterodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human UniProtKB:O94829 ALX4 UniProtKB UniProtKB {GO:0005667=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0005634=PMID:19692347, GO:0048704=GO_REF:0000019, GO:0048565=GO_REF:0000019, GO:0042981=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0003677=PMID:11137991, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000019, GO:0001501=PMID:11106354, GO:0007517=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0035116=GO_REF:0000019, GO:0071837=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:0035115=GO_REF:0000019, GO:0001942=PMID:19692347, GO:0042733=GO_REF:0000019} Q9H161 Homeobox protein aristaless-like 4 protein 20100901 {GO:0005667=IEA, GO:0003700=IEA, GO:0046982=IEA, GO:0005634=IDA, GO:0048704=IEA, GO:0048565=IEA, GO:0042981=IEA, GO:0009791=IEA, GO:0009952=IEA, GO:0003677=NAS, GO:0006351=IEA, GO:0043565=IEA, GO:0001501=NAS, GO:0007517=IEA, GO:0045944=IEA, GO:0035116=IEA, GO:0071837=IEA, GO:0060021=IEA, GO:0035115=IEA, GO:0001942=IMP, GO:0042733=IEA} anterior/posterior pattern specification, digestive tract development, embryonic digit morphogenesis, embryonic forelimb morphogenesis, embryonic hindlimb morphogenesis, embryonic skeletal system morphogenesis, hair follicle development, muscle organ development, palate development, positive regulation of transcription from RNA polymerase II promoter, post-embryonic development, regulation of apoptotic process, skeletal system development, transcription, DNA-dependent nucleus, transcription factor complex DNA binding, HMG box domain binding, protein heterodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human AMACR Reactome UniProtKB {GO:0005739=PMID:7649182, GO:0005782=Reactome:REACT_17018, GO:0006699=Reactome:REACT_11054, GO:0005102=PMID:20178365, GO:0008206=Reactome:REACT_11040, GO:0044281=Reactome:REACT_111217, GO:0033540=Reactome:REACT_17017, GO:0003824=GO_REF:0000002, GO:0044255=Reactome:REACT_16957, GO:0005777=PMID:7649182} Q9UHK6 Alpha-methylacyl-CoA racemase protein 20130301 {GO:0005739=IDA, GO:0005782=TAS, GO:0006699=TAS, GO:0005102=IPI, GO:0008206=TAS, GO:0044281=TAS, GO:0033540=TAS, GO:0003824=IEA, GO:0044255=TAS, GO:0005777=IDA} bile acid biosynthetic process, bile acid metabolic process, cellular lipid metabolic process, fatty acid beta-oxidation using acyl-CoA oxidase, small molecule metabolic process mitochondrion, peroxisomal matrix, peroxisome catalytic activity, receptor binding Human AMBN BHF-UCL UniProtKB {GO:0030345=GO_REF:0000029, GO:0008283=GO_REF:0000024, GO:0005578=GO_REF:0000029, GO:0042475=GO_REF:0000002, GO:0030282=GO_REF:0000029, GO:0007155=GO_REF:0000024, GO:0008083=GO_REF:0000024} Q9NP70 Ameloblastin protein 20081126 {GO:0030345=NAS, GO:0008283=ISS, GO:0005578=NAS, GO:0042475=IEA, GO:0030282=NAS, GO:0007155=ISS, GO:0008083=ISS} bone mineralization, cell adhesion, cell proliferation, odontogenesis of dentin-containing tooth proteinaceous extracellular matrix growth factor activity, structural constituent of tooth enamel Human UniProtKB:O55189 AMBP Reactome UniProtKB {GO:0007565=PMID:10097787, GO:0009986=GO_REF:0000019, GO:0005886=PMID:12817471, GO:0004867=PMID:12817471, GO:0036094=GO_REF:0000002, GO:0005576=Reactome:REACT_160303, GO:0005615=GO_REF:0000019, GO:0042803=PMID:11883904, GO:0046904=PMID:14516400, GO:0043231=GO_REF:0000019, GO:0018298=GO_REF:0000037, GO:0030163=GO_REF:0000019, GO:0046329=PMID:12817471, GO:0019862=PMID:11877257, GO:0050777=PMID:10097787, GO:0019855=PMID:12817471, GO:0019048=GO_REF:0000037, GO:0042167=PMID:11877257, GO:0007155=PMID:9570066, GO:0020037=PMID:11877257} P02760 Protein AMBP protein 20120423 {GO:0007565=NAS, GO:0009986=IEA, GO:0005886=IDA, GO:0004867=TAS, GO:0036094=IEA, GO:0005576=TAS, GO:0005615=IEA, GO:0042803=IPI, GO:0046904=NAS, GO:0043231=IEA, GO:0018298=IEA, GO:0030163=IEA, GO:0046329=TAS, GO:0019862=IDA, GO:0050777=NAS, GO:0019855=NAS, GO:0019048=IEA, GO:0042167=NAS, GO:0007155=NAS, GO:0020037=IDA} cell adhesion, female pregnancy, heme catabolic process, negative regulation of JNK cascade, negative regulation of immune response, protein catabolic process, protein-chromophore linkage, virus-host interaction cell surface, extracellular region, extracellular space, intracellular membrane-bounded organelle, plasma membrane IgA binding, calcium channel inhibitor activity, calcium oxalate binding, heme binding, protein homodimerization activity, serine-type endopeptidase inhibitor activity, small molecule binding Human AMBRA1 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0005737=PMID:17589504, GO:0005776=GO_REF:0000039, GO:0043065=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0021915=GO_REF:0000019, GO:0006914=GO_REF:0000019, GO:0031410=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q9C0C7 Activating molecule in BECN1-regulated autophagy protein 1 protein 20130415 {GO:0005515=IPI, GO:0005737=IDA, GO:0005776=IEA, GO:0043065=IEA, GO:0008285=IEA, GO:0021915=IEA, GO:0006914=IEA, GO:0031410=IEA, GO:0030154=IEA} autophagy, cell differentiation, negative regulation of cell proliferation, neural tube development, positive regulation of apoptotic process autophagic vacuole, cytoplasm, cytoplasmic vesicle protein binding Human UniProtKB:P12504 AMD1 InterPro UniProtKB {GO:0008295=GO_REF:0000002, GO:0034641=Reactome:REACT_13, GO:0004014=GO_REF:0000002, GO:0006597=GO_REF:0000002, GO:0006595=Reactome:REACT_14820, GO:0006557=GO_REF:0000041, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_14840} Q5VXN5 cDNA, FLJ79370, highly similar to S-adenosylmethionine decarboxylase proenzyme (EC 4.1.1.50) protein 20130413 {GO:0008295=IEA, GO:0034641=TAS, GO:0004014=IEA, GO:0006597=IEA, GO:0006595=TAS, GO:0006557=IEA, GO:0044281=TAS, GO:0005829=TAS} S-adenosylmethioninamine biosynthetic process, cellular nitrogen compound metabolic process, polyamine metabolic process, small molecule metabolic process, spermidine biosynthetic process, spermine biosynthetic process cytosol adenosylmethionine decarboxylase activity Human InterPro:IPR001985|InterPro:IPR016067 AMDHD1 BHF-UCL UniProtKB {GO:0003674=GO_REF:0000015, GO:0034641=Reactome:REACT_13, GO:0050480=GO_REF:0000003, GO:0019557=GO_REF:0000041, GO:0019556=GO_REF:0000041, GO:0006548=Reactome:REACT_1249, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_573} Q96NU7 Probable imidazolonepropionase protein 20120523 {GO:0003674=ND, GO:0034641=TAS, GO:0050480=IEA, GO:0019557=IEA, GO:0019556=IEA, GO:0006548=TAS, GO:0044281=TAS, GO:0046872=IEA, GO:0005829=TAS} cellular nitrogen compound metabolic process, histidine catabolic process, histidine catabolic process to glutamate and formamide, histidine catabolic process to glutamate and formate, small molecule metabolic process cytosol imidazolonepropionase activity, metal ion binding, molecular_function Human AMDHD2 UniProtKB UniProtKB {GO:0016787=GO_REF:0000002, GO:0016810=GO_REF:0000002, GO:0005975=GO_REF:0000037, GO:0006044=GO_REF:0000002, GO:0008448=PMID:22692205, GO:0019262=PMID:22692205, GO:0046872=GO_REF:0000037} Q9Y303 Putative N-acetylglucosamine-6-phosphate deacetylase protein 20121102 {GO:0016787=IEA, GO:0016810=IEA, GO:0005975=IEA, GO:0006044=IEA, GO:0008448=IDA, GO:0019262=TAS, GO:0046872=IEA} N-acetylglucosamine metabolic process, N-acetylneuraminate catabolic process, carbohydrate metabolic process N-acetylglucosamine-6-phosphate deacetylase activity, hydrolase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, metal ion binding Human AMELX BHF-UCL UniProtKB {GO:0005515=PMID:18434575, GO:0030345=PMID:2509010, GO:0043498=PMID:1734713, GO:0034505=PMID:1483698, GO:0008283=PMID:1734713, GO:0070172=PMID:2509010, GO:0070166=PMID:1916828, GO:0005578=PMID:2509010, GO:0050801=PMID:2509010, GO:0001837=PMID:1734713, GO:0031214=PMID:2509010, GO:0001649=PMID:1734713, GO:0042802=PMID:1734713, GO:0007165=PMID:16674683, GO:0032967=PMID:1734713, GO:0046848=PMID:1734713, GO:0002062=PMID:1734713, GO:0042475=PMID:1734713, GO:0007155=PMID:1734713, GO:0008083=PMID:1734713} Q99217 Amelogenin, X isoform protein 20081126 {GO:0005515=IPI, GO:0030345=IDA, GO:0043498=ISS, GO:0034505=IMP, GO:0008283=ISS, GO:0070172=TAS, GO:0070166=IMP, GO:0005578=IDA, GO:0050801=TAS, GO:0001837=ISS, GO:0031214=TAS, GO:0001649=ISS, GO:0042802=ISS, GO:0007165=TAS, GO:0032967=ISS, GO:0046848=ISS, GO:0002062=ISS, GO:0042475=ISS, GO:0007155=ISS, GO:0008083=ISS} biomineral tissue development, cell adhesion, cell proliferation, chondrocyte differentiation, enamel mineralization, epithelial to mesenchymal transition, ion homeostasis, odontogenesis of dentin-containing tooth, osteoblast differentiation, positive regulation of collagen biosynthetic process, positive regulation of tooth mineralization, signal transduction, tooth mineralization proteinaceous extracellular matrix cell surface binding, growth factor activity, hydroxyapatite binding, identical protein binding, protein binding, structural constituent of tooth enamel Human AMFR PINC UniProtKB {GO:0005515=PMID:17681147, GO:0000209=PMID:19103148, GO:0006511=PMID:17043353, GO:0004842=PMID:19103148, GO:0006928=PMID:1649192, GO:0030176=PMID:11724934, GO:0030433=PMID:16168377, GO:0051259=PMID:17310145, GO:0030968=PMID:17157811, GO:0007165=PMID:1649192, GO:0008270=GO_REF:0000002, GO:0004872=PMID:1649192, GO:0016021=PMID:1649192} Q9UKV5 E3 ubiquitin-protein ligase AMFR protein 20030904 {GO:0005515=IPI, GO:0000209=IDA, GO:0006511=IMP, GO:0004842=IDA, GO:0006928=TAS, GO:0030176=IDA, GO:0030433=IMP, GO:0051259=IDA, GO:0030968=IMP, GO:0007165=TAS, GO:0008270=IEA, GO:0004872=IPI, GO:0016021=NAS} ER-associated protein catabolic process, cellular component movement, endoplasmic reticulum unfolded protein response, protein oligomerization, protein polyubiquitination, signal transduction, ubiquitin-dependent protein catabolic process integral to endoplasmic reticulum membrane, integral to membrane protein binding, receptor activity, ubiquitin-protein ligase activity, zinc ion binding Human AMH PINC UniProtKB {GO:0008406=GO_REF:0000002, GO:0014070=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0001655=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0007267=PMID:3754790, GO:0005102=PMID:14750901, GO:0005576=PMID:14750901, GO:0005160=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0030154=GO_REF:0000037, GO:0001546=GO_REF:0000019, GO:0007530=PMID:3754790, GO:0010628=PMID:14695376, GO:0007506=GO_REF:0000037, GO:0005737=GO_REF:0000019, GO:0051092=GO_REF:0000019, GO:0005179=PMID:3754790, GO:0001880=PMID:14695376, GO:0007548=PMID:12834017, GO:0008083=GO_REF:0000037} P03971 Muellerian-inhibiting factor protein 20030904 {GO:0008406=IEA, GO:0014070=IEA, GO:0042493=IEA, GO:0001655=IEA, GO:0007568=IEA, GO:0007267=TAS, GO:0005102=IPI, GO:0005576=NAS, GO:0005160=IEA, GO:0005615=IEA, GO:0030154=IEA, GO:0001546=IEA, GO:0007530=TAS, GO:0010628=IMP, GO:0007506=IEA, GO:0005737=IEA, GO:0051092=IEA, GO:0005179=TAS, GO:0001880=IDA, GO:0007548=TAS, GO:0008083=IEA} Mullerian duct regression, aging, cell differentiation, cell-cell signaling, gonad development, gonadal mesoderm development, positive regulation of NF-kappaB transcription factor activity, positive regulation of gene expression, preantral ovarian follicle growth, response to drug, response to organic cyclic compound, sex determination, sex differentiation, urogenital system development cytoplasm, extracellular region, extracellular space growth factor activity, hormone activity, receptor binding, transforming growth factor beta receptor binding Human AMHR2 IntAct UniProtKB {GO:0005515=PMID:22939624, GO:0007165=PMID:7493017, GO:0005887=GO_REF:0000019, GO:0042562=PMID:14750901, GO:0001880=PMID:14750901, GO:0004872=PMID:7493017, GO:0007548=PMID:12834017, GO:0007179=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0005026=GO_REF:0000019} Q16671 Anti-Muellerian hormone type-2 receptor protein 20130415 {GO:0005515=IPI, GO:0007165=IMP, GO:0005887=IEA, GO:0042562=IPI, GO:0001880=NAS, GO:0004872=IMP, GO:0007548=TAS, GO:0007179=IEA, GO:0005524=IEA, GO:0046872=IEA, GO:0005026=IEA} Mullerian duct regression, sex differentiation, signal transduction, transforming growth factor beta receptor signaling pathway integral to plasma membrane ATP binding, hormone binding, metal ion binding, protein binding, receptor activity, transforming growth factor beta receptor activity, type II Human UniProtKB:P08238 AMICA1 Reactome UniProtKB {GO:0005886=Reactome:REACT_12064, GO:0007596=Reactome:REACT_604, GO:0050776=Reactome:REACT_11152, GO:0030593=PMID:15800062, GO:0005923=PMID:15800062, GO:0016021=GO_REF:0000037, GO:0050900=Reactome:REACT_12051, GO:0050839=PMID:15800062, GO:0070633=PMID:15800062, GO:0007157=PMID:15800062} Q86YT9 Junctional adhesion molecule-like protein 20110826 {GO:0005886=TAS, GO:0007596=TAS, GO:0050776=TAS, GO:0030593=IMP, GO:0005923=IDA, GO:0016021=IEA, GO:0050900=TAS, GO:0050839=IPI, GO:0070633=IMP, GO:0007157=IDA} blood coagulation, heterophilic cell-cell adhesion, leukocyte migration, neutrophil chemotaxis, regulation of immune response, transepithelial transport integral to membrane, plasma membrane, tight junction cell adhesion molecule binding Human AMIGO1 UniProtKB UniProtKB {GO:0030424=GO_REF:0000039, GO:0007413=PMID:12629050, GO:0005886=GO_REF:0000039, GO:0042552=PMID:12629050, GO:0050772=PMID:12629050, GO:0016021=GO_REF:0000019, GO:0007156=PMID:12629050, GO:0007157=PMID:12629050} Q86WK6 Amphoterin-induced protein 1 protein 20050517 {GO:0030424=IEA, GO:0007413=ISS, GO:0005886=IEA, GO:0042552=ISS, GO:0050772=ISS, GO:0016021=IEA, GO:0007156=ISS, GO:0007157=ISS} axonal fasciculation, heterophilic cell-cell adhesion, homophilic cell adhesion, myelination, positive regulation of axonogenesis axon, integral to membrane, plasma membrane Human UniProtKB:Q80ZD7 AMIGO2 IntAct UniProtKB {GO:0005515=PMID:21078624, GO:0043069=PMID:12843293, GO:0043066=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0007156=PMID:12629050, GO:0007157=PMID:12629050} Q86SJ2 Amphoterin-induced protein 2 protein 20130415 {GO:0005515=IPI, GO:0043069=ISS, GO:0043066=IEA, GO:0005886=IEA, GO:0005634=IEA, GO:0016021=IEA, GO:0007156=ISS, GO:0007157=ISS} heterophilic cell-cell adhesion, homophilic cell adhesion, negative regulation of apoptotic process, negative regulation of programmed cell death integral to membrane, nucleus, plasma membrane protein binding Human UniProtKB:O00555 AMIGO3 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0007157=PMID:12629050} Q86WK7 Amphoterin-induced protein 3 protein 20050517 {GO:0016021=IEA, GO:0007157=ISS} heterophilic cell-cell adhesion integral to membrane Human UniProtKB:Q80ZD5 AMMECR1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q9Y4X0 AMME syndrome candidate gene 1 protein protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human AMMECR1L null null {} null null null null {} null null null AMN Reactome UniProtKB {GO:0006629=Reactome:REACT_602, GO:0007588=GO_REF:0000019, GO:0008104=GO_REF:0000019, GO:0005886=Reactome:REACT_13688, GO:0042157=Reactome:REACT_13621, GO:0045177=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037} Q9BXJ7 Protein amnionless protein 20080410 {GO:0006629=TAS, GO:0007588=IEA, GO:0008104=IEA, GO:0005886=TAS, GO:0042157=TAS, GO:0045177=IEA, GO:0007275=IEA, GO:0044281=TAS, GO:0016021=IEA} excretion, lipid metabolic process, lipoprotein metabolic process, multicellular organismal development, protein localization, small molecule metabolic process apical part of cell, integral to membrane, plasma membrane Human AMOT IntAct UniProtKB {GO:0005515=PMID:21481793, GO:0030036=PMID:16043488, GO:0005884=PMID:11257124, GO:0030139=PMID:11257124, GO:0005829=Reactome:REACT_118821, GO:0042074=GO_REF:0000019, GO:0006935=GO_REF:0000019, GO:0008180=PMID:18850735, GO:0040019=GO_REF:0000019, GO:0004872=PMID:11257124, GO:0034260=GO_REF:0000019, GO:0030334=PMID:11257124, GO:0003365=GO_REF:0000019, GO:0051056=GO_REF:0000019, GO:0031410=GO_REF:0000019, GO:0035329=Reactome:REACT_118607, GO:0001701=GO_REF:0000019, GO:0001726=PMID:11257124, GO:0030027=PMID:11257124, GO:0001702=GO_REF:0000019, GO:0043534=GO_REF:0000019, GO:0043532=PMID:11257124, GO:0016525=PMID:11257124, GO:0005923=GO_REF:0000039, GO:0034613=PMID:21205866, GO:0001570=GO_REF:0000019, GO:0009897=PMID:11257124} Q4VCS5 Angiomotin protein 20130415 {GO:0005515=IPI, GO:0030036=TAS, GO:0005884=IDA, GO:0030139=IDA, GO:0005829=TAS, GO:0042074=IEA, GO:0006935=IEA, GO:0008180=IDA, GO:0040019=IEA, GO:0004872=IDA, GO:0034260=IEA, GO:0030334=IDA, GO:0003365=IEA, GO:0051056=IEA, GO:0031410=IEA, GO:0035329=TAS, GO:0001701=IEA, GO:0001726=IDA, GO:0030027=IDA, GO:0001702=IEA, GO:0043534=IEA, GO:0043532=IDA, GO:0016525=IDA, GO:0005923=IEA, GO:0034613=IDA, GO:0001570=IEA, GO:0009897=IDA} actin cytoskeleton organization, blood vessel endothelial cell migration, cell migration involved in gastrulation, cellular protein localization, chemotaxis, establishment of cell polarity involved in ameboidal cell migration, gastrulation with mouth forming second, hippo signaling cascade, in utero embryonic development, negative regulation of GTPase activity, negative regulation of angiogenesis, positive regulation of embryonic development, regulation of cell migration, regulation of small GTPase mediated signal transduction, vasculogenesis actin filament, cytoplasmic vesicle, cytosol, endocytic vesicle, external side of plasma membrane, lamellipodium, ruffle, signalosome, tight junction angiostatin binding, protein binding, receptor activity Human UniProtKB:Q68EM7 AMOTL1 HPA UniProtKB {GO:0005515=PMID:21187284, GO:0003365=GO_REF:0000019, GO:0030054=GO_REF:0000052, GO:0035329=Reactome:REACT_118607, GO:0031410=GO_REF:0000019, GO:0030027=GO_REF:0000019, GO:0042802=PMID:16019084, GO:0005829=Reactome:REACT_118821, GO:0043536=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0016324=GO_REF:0000019, GO:0008180=PMID:18850735, GO:0005923=PMID:16019084, GO:0016055=GO_REF:0000037} Q8IY63 Angiomotin-like protein 1 protein 20080818 {GO:0005515=IPI, GO:0003365=IEA, GO:0030054=IDA, GO:0035329=TAS, GO:0031410=IEA, GO:0030027=IEA, GO:0042802=IDA, GO:0005829=TAS, GO:0043536=IEA, GO:0005737=IDA, GO:0016324=IEA, GO:0008180=IDA, GO:0005923=IDA, GO:0016055=IEA} Wnt receptor signaling pathway, establishment of cell polarity involved in ameboidal cell migration, hippo signaling cascade, positive regulation of blood vessel endothelial cell migration apical plasma membrane, cell junction, cytoplasm, cytoplasmic vesicle, cytosol, lamellipodium, signalosome, tight junction identical protein binding, protein binding Human AMOTL2 Reactome UniProtKB {GO:0005515=PMID:21187284, GO:0016324=GO_REF:0000019, GO:0035329=Reactome:REACT_118607, GO:0031410=GO_REF:0000019, GO:0005923=GO_REF:0000019, GO:0055037=GO_REF:0000039, GO:0016055=GO_REF:0000037, GO:0005829=Reactome:REACT_118821, GO:0042802=GO_REF:0000019} Q9Y2J4 Angiomotin-like protein 2 protein 20130301 {GO:0005515=IPI, GO:0016324=IEA, GO:0035329=TAS, GO:0031410=IEA, GO:0005923=IEA, GO:0055037=IEA, GO:0016055=IEA, GO:0005829=TAS, GO:0042802=IEA} Wnt receptor signaling pathway, hippo signaling cascade apical plasma membrane, cytoplasmic vesicle, cytosol, recycling endosome, tight junction identical protein binding, protein binding Human AMPD1 Reactome UniProtKB {GO:0003876=GO_REF:0000003, GO:0010033=GO_REF:0000019, GO:0006144=Reactome:REACT_522, GO:0032264=GO_REF:0000041, GO:0043101=Reactome:REACT_1923, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_700, GO:0032036=GO_REF:0000019} P23109 AMP deaminase 1 protein 20130213 {GO:0003876=IEA, GO:0010033=IEA, GO:0006144=TAS, GO:0032264=IEA, GO:0043101=TAS, GO:0055086=TAS, GO:0044281=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0032036=IEA} IMP salvage, nucleobase-containing small molecule metabolic process, purine nucleobase metabolic process, purine-containing compound salvage, response to organic substance, small molecule metabolic process cytosol AMP deaminase activity, metal ion binding, myosin heavy chain binding Human AMPD2 Reactome UniProtKB {GO:0003876=PMID:8764830, GO:0006144=Reactome:REACT_522, GO:0032264=GO_REF:0000041, GO:0043101=Reactome:REACT_1923, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0005575=GO_REF:0000015, GO:0006188=GO_REF:0000002, GO:0006163=GO_REF:0000029, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_700} Q01433 AMP deaminase 2 protein 20130213 {GO:0003876=NAS, GO:0006144=TAS, GO:0032264=IEA, GO:0043101=TAS, GO:0055086=TAS, GO:0044281=TAS, GO:0005575=ND, GO:0006188=IEA, GO:0006163=NAS, GO:0046872=IEA, GO:0005829=TAS} IMP biosynthetic process, IMP salvage, nucleobase-containing small molecule metabolic process, purine nucleobase metabolic process, purine nucleotide metabolic process, purine-containing compound salvage, small molecule metabolic process cellular_component, cytosol AMP deaminase activity, metal ion binding Human AMPD3 Reactome UniProtKB {GO:0003876=GO_REF:0000003, GO:0006196=PMID:9291127, GO:0006144=Reactome:REACT_522, GO:0032264=GO_REF:0000041, GO:0043101=Reactome:REACT_1923, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0006188=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_700} Q01432 AMP deaminase 3 protein 20130213 {GO:0003876=IEA, GO:0006196=TAS, GO:0006144=TAS, GO:0032264=IEA, GO:0043101=TAS, GO:0055086=TAS, GO:0044281=TAS, GO:0006188=IEA, GO:0046872=IEA, GO:0005829=TAS} AMP catabolic process, IMP biosynthetic process, IMP salvage, nucleobase-containing small molecule metabolic process, purine nucleobase metabolic process, purine-containing compound salvage, small molecule metabolic process cytosol AMP deaminase activity, metal ion binding Human AMPH PINC UniProtKB {GO:0005515=PMID:20946875, GO:0005737=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0007268=PMID:9182667, GO:0030672=GO_REF:0000039, GO:0048488=GO_REF:0000019, GO:0007612=GO_REF:0000019, GO:0015629=PMID:9182667, GO:0008021=PMID:1628617, GO:0006897=PMID:9182667} P49418 Amphiphysin protein 20030904 {GO:0005515=IPI, GO:0005737=IEA, GO:0030054=IEA, GO:0007268=TAS, GO:0030672=IEA, GO:0048488=IEA, GO:0007612=IEA, GO:0015629=TAS, GO:0008021=TAS, GO:0006897=TAS} endocytosis, learning, synaptic transmission, synaptic vesicle endocytosis actin cytoskeleton, cell junction, cytoplasm, synaptic vesicle, synaptic vesicle membrane protein binding Human AMY1A InterPro UniProtKB {GO:0005515=PMID:16203048, GO:0005975=GO_REF:0000002, GO:0007586=PMID:2423416, GO:0005576=GO_REF:0000039, GO:0003824=GO_REF:0000002, GO:0004556=GO_REF:0000003, GO:0046872=GO_REF:0000037} Q5T084 Alpha-amylase 1 protein 20130413 {GO:0005515=IPI, GO:0005975=IEA, GO:0007586=TAS, GO:0005576=IEA, GO:0003824=IEA, GO:0004556=IEA, GO:0046872=IEA} carbohydrate metabolic process, digestion extracellular region alpha-amylase activity, catalytic activity, metal ion binding, protein binding Human InterPro:IPR013781 AMY1B InterPro UniProtKB {GO:0043169=GO_REF:0000002, GO:0005975=GO_REF:0000002, GO:0003824=GO_REF:0000002} Q5T085 Alpha-amylase 1 protein 20130413 {GO:0043169=IEA, GO:0005975=IEA, GO:0003824=IEA} carbohydrate metabolic process catalytic activity, cation binding Human InterPro:IPR006046|InterPro:IPR006047 AMY1C null null {} null null null null {} null null null AMY2A Reactome UniProtKB {GO:0031404=PMID:10769135, GO:0016052=PMID:10769135, GO:0043169=GO_REF:0000002, GO:0005975=Reactome:REACT_474, GO:0005509=PMID:10769135, GO:0044245=Reactome:REACT_9472, GO:0005576=Reactome:REACT_9475, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0004556=PMID:10769135, GO:0005615=PMID:10769135} P04746 Pancreatic alpha-amylase protein 20130301 {GO:0031404=IDA, GO:0016052=IDA, GO:0043169=IEA, GO:0005975=TAS, GO:0005509=IDA, GO:0044245=TAS, GO:0005576=TAS, GO:0044281=TAS, GO:0003824=IEA, GO:0004556=IDA, GO:0005615=IDA} carbohydrate catabolic process, carbohydrate metabolic process, polysaccharide digestion, small molecule metabolic process extracellular region, extracellular space alpha-amylase activity, calcium ion binding, catalytic activity, cation binding, chloride ion binding Human AMZ2 UniProtKB UniProtKB {GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0008237=GO_REF:0000037} Q86W34 Archaemetzincin-2 protein 20130413 {GO:0006508=IEA, GO:0008270=IEA, GO:0008237=IEA} proteolysis metallopeptidase activity, zinc ion binding Human UniProtKB-KW:KW-0482 ANAPC1 Reactome UniProtKB {GO:0007094=Reactome:REACT_2137, GO:0051437=Reactome:REACT_6904, GO:0051436=Reactome:REACT_6785, GO:0031145=Reactome:REACT_6871, GO:0051439=Reactome:REACT_6867, GO:0005829=Reactome:REACT_9035, GO:0070979=PMID:18485873, GO:0005680=PMID:16364912, GO:0000087=Reactome:REACT_910, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9051, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q9H1A4 Anaphase-promoting complex subunit 1 protein 20130301 {GO:0007094=TAS, GO:0051437=TAS, GO:0051436=TAS, GO:0031145=TAS, GO:0051439=TAS, GO:0005829=TAS, GO:0070979=IDA, GO:0005680=IDA, GO:0000087=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle checkpoint, cell division, mitotic anaphase, mitotic cell cycle, mitotic spindle assembly checkpoint, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K11-linked ubiquitination, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle anaphase-promoting complex, cytosol, nucleoplasm Human ANAPC10 Reactome UniProtKB {GO:0007094=Reactome:REACT_2137, GO:0006511=PMID:10318877, GO:0004842=PMID:10318877, GO:0051437=Reactome:REACT_6904, GO:0051436=Reactome:REACT_6785, GO:0031145=Reactome:REACT_6871, GO:0051439=Reactome:REACT_6867, GO:0005829=Reactome:REACT_9035, GO:0005737=GO_REF:0000019, GO:0007067=PMID:10318877, GO:0070979=PMID:18485873, GO:0005680=PMID:21926987, GO:0000086=PMID:10318877, GO:0000087=Reactome:REACT_910, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9051, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q9UM13 Anaphase-promoting complex subunit 10 protein 20130301 {GO:0007094=TAS, GO:0006511=TAS, GO:0004842=TAS, GO:0051437=TAS, GO:0051436=TAS, GO:0031145=TAS, GO:0051439=TAS, GO:0005829=TAS, GO:0005737=IEA, GO:0007067=NAS, GO:0070979=IDA, GO:0005680=IDA, GO:0000086=TAS, GO:0000087=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle checkpoint, cell division, mitosis, mitotic anaphase, mitotic cell cycle, mitotic spindle assembly checkpoint, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K11-linked ubiquitination, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, ubiquitin-dependent protein catabolic process anaphase-promoting complex, cytoplasm, cytosol, nucleoplasm ubiquitin-protein ligase activity Human ANAPC11 Reactome UniProtKB {GO:0007094=Reactome:REACT_2137, GO:0004842=PMID:11739784, GO:0016567=PMID:11739784, GO:0051437=Reactome:REACT_6904, GO:0051436=Reactome:REACT_6785, GO:0031145=Reactome:REACT_6871, GO:0051439=Reactome:REACT_6867, GO:0005829=Reactome:REACT_9035, GO:0007067=PMID:11739784, GO:0070979=PMID:18485873, GO:0005680=PMID:21926987, GO:0000087=Reactome:REACT_910, GO:0000075=Reactome:REACT_1538, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_9051, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q9NYG5 Anaphase-promoting complex subunit 11 protein 20130301 {GO:0007094=TAS, GO:0004842=IDA, GO:0016567=IDA, GO:0051437=TAS, GO:0051436=TAS, GO:0031145=TAS, GO:0051439=TAS, GO:0005829=TAS, GO:0007067=TAS, GO:0070979=IDA, GO:0005680=IDA, GO:0000087=TAS, GO:0000075=TAS, GO:0008270=IEA, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle checkpoint, cell division, mitosis, mitotic anaphase, mitotic cell cycle, mitotic spindle assembly checkpoint, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K11-linked ubiquitination, protein ubiquitination, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle anaphase-promoting complex, cytosol, nucleoplasm ubiquitin-protein ligase activity, zinc ion binding Human ANAPC13 UniProtKB UniProtKB {GO:0007067=GO_REF:0000037, GO:0070979=PMID:18485873, GO:0005680=PMID:16364912, GO:0051301=GO_REF:0000037} Q9BS18 Anaphase-promoting complex subunit 13 protein 20091027 {GO:0007067=IEA, GO:0070979=IDA, GO:0005680=IDA, GO:0051301=IEA} cell division, mitosis, protein K11-linked ubiquitination anaphase-promoting complex Human ANAPC16 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0007067=GO_REF:0000037, GO:0016567=PMID:20360068, GO:0005680=PMID:20360068, GO:0051301=GO_REF:0000037} Q96DE5 Anaphase-promoting complex subunit 16 protein 20110516 {GO:0005737=IDA, GO:0007067=IEA, GO:0016567=IDA, GO:0005680=IDA, GO:0051301=IEA} cell division, mitosis, protein ubiquitination anaphase-promoting complex, cytoplasm Human ANAPC2 Reactome UniProtKB {GO:0007094=Reactome:REACT_2137, GO:0006511=PMID:9469815, GO:0090129=GO_REF:0000024, GO:0004842=PMID:9469815, GO:0051437=Reactome:REACT_6904, GO:0051436=Reactome:REACT_6785, GO:0000079=PMID:9469815, GO:0031145=Reactome:REACT_6871, GO:0051439=Reactome:REACT_6867, GO:0030154=GO_REF:0000037, GO:0005829=Reactome:REACT_9035, GO:0007399=GO_REF:0000037, GO:0008054=PMID:9469815, GO:0031915=GO_REF:0000024, GO:0070979=PMID:18485873, GO:0005680=PMID:16364912, GO:0000087=Reactome:REACT_910, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9051, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0031625=GO_REF:0000002, GO:0051301=GO_REF:0000037} Q9UJX6 Anaphase-promoting complex subunit 2 protein 20130301 {GO:0007094=TAS, GO:0006511=TAS, GO:0090129=ISS, GO:0004842=TAS, GO:0051437=TAS, GO:0051436=TAS, GO:0000079=TAS, GO:0031145=TAS, GO:0051439=TAS, GO:0030154=IEA, GO:0005829=TAS, GO:0007399=IEA, GO:0008054=TAS, GO:0031915=ISS, GO:0070979=IDA, GO:0005680=IDA, GO:0000087=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0031625=IEA, GO:0051301=IEA} M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle checkpoint, cell differentiation, cell division, cyclin catabolic process, mitotic anaphase, mitotic cell cycle, mitotic spindle assembly checkpoint, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, nervous system development, positive regulation of synapse maturation, positive regulation of synaptic plasticity, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K11-linked ubiquitination, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, ubiquitin-dependent protein catabolic process anaphase-promoting complex, cytosol, nucleoplasm ubiquitin protein ligase binding, ubiquitin-protein ligase activity Human ANAPC4 BHF-UCL UniProtKB {GO:0007094=Reactome:REACT_2137, GO:0006511=PMID:9469815, GO:0004842=PMID:6180011, GO:0019903=PMID:21241890, GO:0051437=Reactome:REACT_6904, GO:0005634=PMID:21241890, GO:0051436=Reactome:REACT_6785, GO:0031145=Reactome:REACT_6871, GO:0051439=Reactome:REACT_6867, GO:0005829=Reactome:REACT_9035, GO:0007067=PMID:9469815, GO:0070979=PMID:18485873, GO:0005680=PMID:21926987, GO:0000086=PMID:9469815, GO:0000087=Reactome:REACT_910, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9051, GO:0030071=GO_REF:0000002, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q9UJX5 Anaphase-promoting complex subunit 4 protein 20110421 {GO:0007094=TAS, GO:0006511=TAS, GO:0004842=TAS, GO:0019903=IPI, GO:0051437=TAS, GO:0005634=IDA, GO:0051436=TAS, GO:0031145=TAS, GO:0051439=TAS, GO:0005829=TAS, GO:0007067=TAS, GO:0070979=IDA, GO:0005680=IDA, GO:0000086=TAS, GO:0000087=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0030071=IEA, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle checkpoint, cell division, mitosis, mitotic anaphase, mitotic cell cycle, mitotic spindle assembly checkpoint, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K11-linked ubiquitination, regulation of mitotic metaphase/anaphase transition, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, ubiquitin-dependent protein catabolic process anaphase-promoting complex, cytosol, nucleoplasm, nucleus protein phosphatase binding, ubiquitin-protein ligase activity Human ANAPC5 BHF-UCL UniProtKB {GO:0006511=PMID:9469815, GO:0007094=Reactome:REACT_2137, GO:0004842=PMID:9469815, GO:0019903=PMID:21241890, GO:0051437=Reactome:REACT_6904, GO:0005634=PMID:21241890, GO:0051436=Reactome:REACT_6785, GO:0031145=Reactome:REACT_6871, GO:0051439=Reactome:REACT_6867, GO:0005829=Reactome:REACT_9035, GO:0070979=PMID:18485873, GO:0005680=PMID:16364912, GO:0000086=PMID:9469815, GO:0000087=Reactome:REACT_910, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9051, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q9UJX4 Anaphase-promoting complex subunit 5 protein 20110421 {GO:0006511=TAS, GO:0007094=TAS, GO:0004842=TAS, GO:0019903=IPI, GO:0051437=TAS, GO:0005634=IDA, GO:0051436=TAS, GO:0031145=TAS, GO:0051439=TAS, GO:0005829=TAS, GO:0070979=IDA, GO:0005680=IDA, GO:0000086=TAS, GO:0000087=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle checkpoint, cell division, mitotic anaphase, mitotic cell cycle, mitotic spindle assembly checkpoint, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K11-linked ubiquitination, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, ubiquitin-dependent protein catabolic process anaphase-promoting complex, cytosol, nucleoplasm, nucleus protein phosphatase binding, ubiquitin-protein ligase activity Human ANAPC7 BHF-UCL UniProtKB {GO:0007094=Reactome:REACT_2137, GO:0019903=PMID:21241890, GO:0051437=Reactome:REACT_6904, GO:0005634=PMID:21241890, GO:0051436=Reactome:REACT_6785, GO:0031145=Reactome:REACT_6871, GO:0051439=Reactome:REACT_6867, GO:0005829=Reactome:REACT_9035, GO:0070979=PMID:18485873, GO:0005680=PMID:21926987, GO:0000087=Reactome:REACT_910, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9051, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q9UJX3 Anaphase-promoting complex subunit 7 protein 20110421 {GO:0007094=TAS, GO:0019903=IPI, GO:0051437=TAS, GO:0005634=IDA, GO:0051436=TAS, GO:0031145=TAS, GO:0051439=TAS, GO:0005829=TAS, GO:0070979=IDA, GO:0005680=IDA, GO:0000087=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle checkpoint, cell division, mitotic anaphase, mitotic cell cycle, mitotic spindle assembly checkpoint, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K11-linked ubiquitination, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle anaphase-promoting complex, cytosol, nucleoplasm, nucleus protein phosphatase binding Human ANG IntAct UniProtKB {GO:0005515=PMID:15737636, GO:0017148=GO_REF:0000037, GO:0008219=GO_REF:0000037, GO:0009303=PMID:15735021, GO:0050714=PMID:2646638, GO:0005634=PMID:10649442, GO:0019843=PMID:2457905, GO:0007202=PMID:2457905, GO:0001556=PMID:11438326, GO:0005615=PMID:16490744, GO:0032431=PMID:2646638, GO:0030426=GO_REF:0000024, GO:0001541=PMID:12770725, GO:0007154=PMID:10103013, GO:0032311=PMID:3470787, GO:0032148=PMID:17125737, GO:0030041=GO_REF:0000024, GO:0043025=GO_REF:0000024, GO:0006651=PMID:2457905, GO:0009725=PMID:10999833, GO:0008201=PMID:10103013, GO:0001666=PMID:15776477, GO:0042277=PMID:11782452, GO:0005507=PMID:9245697, GO:0005102=PMID:9122172, GO:0005605=PMID:15166501, GO:0005730=GO_REF:0000024, GO:0042592=PMID:15166501, GO:0048662=PMID:10103013, GO:0004522=GO_REF:0000002, GO:0003779=PMID:7679494, GO:0004540=PMID:2730651, GO:0001890=PMID:11984825, GO:0001525=PMID:8448182, GO:0003677=PMID:10649442, GO:0004519=PMID:10103013, GO:0016477=PMID:17125737, GO:0001938=PMID:9707554, GO:0042327=PMID:17125737} P03950 Angiogenin protein 20130415 {GO:0005515=IPI, GO:0017148=IEA, GO:0008219=IEA, GO:0009303=IMP, GO:0050714=IDA, GO:0005634=IDA, GO:0019843=TAS, GO:0007202=IMP, GO:0001556=NAS, GO:0005615=IDA, GO:0032431=IMP, GO:0030426=ISS, GO:0001541=NAS, GO:0007154=NAS, GO:0032311=IPI, GO:0032148=IMP, GO:0030041=ISS, GO:0043025=ISS, GO:0006651=IDA, GO:0009725=IDA, GO:0008201=IDA, GO:0001666=NAS, GO:0042277=IDA, GO:0005507=IDA, GO:0005102=IDA, GO:0005605=IDA, GO:0005730=ISS, GO:0042592=NAS, GO:0048662=IDA, GO:0004522=IEA, GO:0003779=IDA, GO:0004540=IDA, GO:0001890=NAS, GO:0001525=IDA, GO:0003677=IC, GO:0004519=TAS, GO:0016477=IMP, GO:0001938=IDA, GO:0042327=IDA} actin filament polymerization, activation of phospholipase A2 activity, activation of phospholipase C activity, activation of protein kinase B activity, angiogenesis, cell communication, cell death, cell migration, diacylglycerol biosynthetic process, homeostatic process, negative regulation of smooth muscle cell proliferation, negative regulation of translation, oocyte maturation, ovarian follicle development, placenta development, positive regulation of endothelial cell proliferation, positive regulation of phosphorylation, positive regulation of protein secretion, rRNA transcription, response to hormone stimulus, response to hypoxia angiogenin-PRI complex, basal lamina, extracellular space, growth cone, neuronal cell body, nucleolus, nucleus DNA binding, actin binding, copper ion binding, endonuclease activity, heparin binding, pancreatic ribonuclease activity, peptide binding, protein binding, rRNA binding, receptor binding, ribonuclease activity Human UniProtKB:P35609 ANGEL1 null null {} null null null null {} null null null ANGEL2 null null {} null null null null {} null null null ANGPT1 Reactome UniProtKB {GO:0051897=PMID:18425120, GO:0072012=GO_REF:0000024, GO:0050731=PMID:19689429, GO:0002040=PMID:10218485, GO:0050900=Reactome:REACT_12051, GO:0005615=PMID:8980223, GO:0030154=GO_REF:0000037, GO:0033138=GO_REF:0000019, GO:0007171=PMID:19424712, GO:0031398=PMID:19689429, GO:0070374=PMID:18425120, GO:0030097=GO_REF:0000019, GO:0030971=PMID:19922791, GO:0043066=PMID:10218485, GO:0048014=PMID:19922791, GO:0031589=GO_REF:0000019, GO:0005102=GO_REF:0000019, GO:0005576=Reactome:REACT_16914, GO:0014068=GO_REF:0000019, GO:0001525=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0045785=GO_REF:0000019, GO:0010595=PMID:12958144, GO:0007162=PMID:19674970, GO:0007596=Reactome:REACT_604, GO:0001936=PMID:8980223, GO:0034394=PMID:19615361, GO:0045121=PMID:19615361, GO:0014842=PMID:19733541, GO:2000352=PMID:19674970, GO:0007169=GO_REF:0000019, GO:0043116=PMID:14978158, GO:0002092=PMID:19424712, GO:0030210=PMID:19297368} Q15389 Angiopoietin-1 protein 20071203 {GO:0051897=IDA, GO:0072012=ISS, GO:0050731=IDA, GO:0002040=IDA, GO:0050900=TAS, GO:0005615=IDA, GO:0030154=IEA, GO:0033138=IEA, GO:0007171=IDA, GO:0031398=IDA, GO:0070374=IDA, GO:0030097=IEA, GO:0030971=IPI, GO:0043066=IDA, GO:0048014=IDA, GO:0031589=IEA, GO:0005102=IEA, GO:0005576=TAS, GO:0014068=IEA, GO:0001525=IEA, GO:0001701=IEA, GO:0045785=IEA, GO:0010595=IDA, GO:0007162=IDA, GO:0007596=TAS, GO:0001936=IDA, GO:0034394=IDA, GO:0045121=IDA, GO:0014842=IDA, GO:2000352=IDA, GO:0007169=IEA, GO:0043116=IDA, GO:0002092=IDA, GO:0030210=IDA} Tie signaling pathway, activation of transmembrane receptor protein tyrosine kinase activity, angiogenesis, blood coagulation, cell differentiation, cell-substrate adhesion, glomerulus vasculature development, hemopoiesis, heparin biosynthetic process, in utero embryonic development, leukocyte migration, negative regulation of apoptotic process, negative regulation of cell adhesion, negative regulation of endothelial cell apoptotic process, negative regulation of vascular permeability, positive regulation of ERK1 and ERK2 cascade, positive regulation of cell adhesion, positive regulation of endothelial cell migration, positive regulation of peptidyl-serine phosphorylation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of protein kinase B signaling cascade, positive regulation of protein ubiquitination, positive regulation of receptor internalization, protein localization to cell surface, regulation of endothelial cell proliferation, regulation of satellite cell proliferation, sprouting angiogenesis, transmembrane receptor protein tyrosine kinase signaling pathway extracellular region, extracellular space, membrane raft receptor binding, receptor tyrosine kinase binding Human ANGPT2 IntAct UniProtKB {GO:0005515=PMID:20708158, GO:0014070=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0031100=GO_REF:0000019, GO:0072012=GO_REF:0000024, GO:0010812=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0042995=GO_REF:0000019, GO:0050900=Reactome:REACT_12051, GO:0007281=GO_REF:0000019, GO:0005615=PMID:9660821, GO:0046872=GO_REF:0000037, GO:0009314=GO_REF:0000019, GO:0014823=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0030971=PMID:19922791, GO:0048014=PMID:19922791, GO:0060135=GO_REF:0000019, GO:0005102=PMID:10766762, GO:0005576=Reactome:REACT_12547, GO:0001525=GO_REF:0000019, GO:0045766=GO_REF:0000019, GO:0009749=GO_REF:0000019, GO:0009612=GO_REF:0000019, GO:0007165=PMID:10766762, GO:0071363=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0016525=GO_REF:0000019, GO:0043537=PMID:9660821} O15123 Angiopoietin-2 protein 20130415 {GO:0005515=IPI, GO:0014070=IEA, GO:0005886=IEA, GO:0031100=IEA, GO:0072012=ISS, GO:0010812=IEA, GO:0005634=IEA, GO:0042995=IEA, GO:0050900=TAS, GO:0007281=IEA, GO:0005615=IDA, GO:0046872=IEA, GO:0009314=IEA, GO:0014823=IEA, GO:0001666=IEA, GO:0030971=IPI, GO:0048014=IDA, GO:0060135=IEA, GO:0005102=TAS, GO:0005576=TAS, GO:0001525=IEA, GO:0045766=IEA, GO:0009749=IEA, GO:0009612=IEA, GO:0007165=TAS, GO:0071363=IEA, GO:0007596=TAS, GO:0016525=IEA, GO:0043537=IDA} Tie signaling pathway, angiogenesis, blood coagulation, cellular response to growth factor stimulus, germ cell development, glomerulus vasculature development, leukocyte migration, maternal process involved in female pregnancy, negative regulation of angiogenesis, negative regulation of blood vessel endothelial cell migration, negative regulation of cell-substrate adhesion, organ regeneration, positive regulation of angiogenesis, response to activity, response to glucose stimulus, response to hypoxia, response to mechanical stimulus, response to organic cyclic compound, response to radiation, signal transduction cell projection, extracellular region, extracellular space, nucleus, plasma membrane metal ion binding, protein binding, receptor binding, receptor tyrosine kinase binding Human UniProtKB:Q02763 ANGPT4 GOC UniProtKB {GO:0030971=PMID:10051567, GO:0043066=PMID:12958144, GO:0050731=PMID:15851516, GO:0071456=PMID:12958144, GO:0005576=Reactome:REACT_12598, GO:0001525=GO_REF:0000037, GO:0050900=Reactome:REACT_12051, GO:0005615=PMID:10025962, GO:0045766=PMID:15284220, GO:0010595=PMID:12958144, GO:0043536=PMID:15284220, GO:0007171=PMID:15851516, GO:0030297=PMID:10051567, GO:0007596=Reactome:REACT_604, GO:0001935=PMID:10025962, GO:0016525=PMID:16790085, GO:0043537=PMID:16790085} Q9Y264 Angiopoietin-4 protein 20130413 {GO:0030971=IDA, GO:0043066=IDA, GO:0050731=IDA, GO:0071456=IEP, GO:0005576=TAS, GO:0001525=IEA, GO:0050900=TAS, GO:0005615=IDA, GO:0045766=IDA, GO:0010595=IDA, GO:0043536=IDA, GO:0007171=IDA, GO:0030297=IDA, GO:0007596=TAS, GO:0001935=IDA, GO:0016525=IDA, GO:0043537=IDA} activation of transmembrane receptor protein tyrosine kinase activity, angiogenesis, blood coagulation, cellular response to hypoxia, endothelial cell proliferation, leukocyte migration, negative regulation of angiogenesis, negative regulation of apoptotic process, negative regulation of blood vessel endothelial cell migration, positive regulation of angiogenesis, positive regulation of blood vessel endothelial cell migration, positive regulation of endothelial cell migration, positive regulation of peptidyl-tyrosine phosphorylation extracellular region, extracellular space receptor tyrosine kinase binding, transmembrane receptor protein tyrosine kinase activator activity Human ANGPTL1 MGI UniProtKB {GO:0005102=GO_REF:0000019, GO:0005615=PMID:10025962, GO:0007169=GO_REF:0000019} O95841 Angiopoietin-related protein 1 protein 20060110 {GO:0005102=IEA, GO:0005615=IDA, GO:0007169=IEA} transmembrane receptor protein tyrosine kinase signaling pathway extracellular space receptor binding Human ANGPTL3 BHF-UCL UniProtKB {GO:0043498=PMID:12565906, GO:0050996=PMID:12565906, GO:0019915=PMID:12565906, GO:0070328=GO_REF:0000024, GO:0048844=GO_REF:0000024, GO:0006071=PMID:12565906, GO:0005615=PMID:17110602, GO:0006631=PMID:12565906, GO:0009725=GO_REF:0000019, GO:0008203=PMID:17110602, GO:0004857=GO_REF:0000024, GO:0042632=PMID:17110602, GO:0004859=PMID:17110602, GO:0030335=PMID:11877390, GO:0055088=PMID:17110602, GO:0045766=PMID:11877390, GO:0010519=PMID:17110602, GO:0051005=PMID:17110602, GO:0007165=PMID:11877390, GO:0005178=PMID:11877390, GO:0007160=PMID:11877390, GO:0007229=PMID:11877390, GO:0055091=PMID:17110602, GO:0055090=PMID:17110602, GO:0006644=PMID:17110602, GO:0008083=PMID:11877390, GO:0009395=PMID:17110602} Q9Y5C1 Angiopoietin-related protein 3 protein 20080121 {GO:0043498=IDA, GO:0050996=IDA, GO:0019915=IDA, GO:0070328=ISS, GO:0048844=ISS, GO:0006071=IDA, GO:0005615=IDA, GO:0006631=IDA, GO:0009725=IEA, GO:0008203=IDA, GO:0004857=ISS, GO:0042632=IDA, GO:0004859=IDA, GO:0030335=IDA, GO:0055088=IDA, GO:0045766=IDA, GO:0010519=IDA, GO:0051005=IDA, GO:0007165=IDA, GO:0005178=IPI, GO:0007160=IPI, GO:0007229=NAS, GO:0055091=IDA, GO:0055090=IDA, GO:0006644=IDA, GO:0008083=IDA, GO:0009395=IDA} acylglycerol homeostasis, artery morphogenesis, cell-matrix adhesion, cholesterol homeostasis, cholesterol metabolic process, fatty acid metabolic process, glycerol metabolic process, integrin-mediated signaling pathway, lipid homeostasis, lipid storage, negative regulation of lipoprotein lipase activity, negative regulation of phospholipase activity, phospholipid catabolic process, phospholipid homeostasis, phospholipid metabolic process, positive regulation of angiogenesis, positive regulation of cell migration, positive regulation of lipid catabolic process, response to hormone stimulus, signal transduction, triglyceride homeostasis extracellular space cell surface binding, enzyme inhibitor activity, growth factor activity, integrin binding, phospholipase inhibitor activity Human ANGPTL4 BHF-UCL UniProtKB {GO:0005515=PMID:21397862, GO:0004857=GO_REF:0000024, GO:0001666=PMID:12707035, GO:0043066=PMID:10698685, GO:0005578=GO_REF:0000039, GO:0070328=GO_REF:0000024, GO:0005576=Reactome:REACT_27173, GO:0044281=Reactome:REACT_111217, GO:0001525=GO_REF:0000037, GO:0005615=PMID:10698685, GO:0030154=GO_REF:0000037, GO:0045766=PMID:11953136, GO:0051005=PMID:19542565, GO:0051260=GO_REF:0000019, GO:0044255=Reactome:REACT_22279} Q9BY76 Angiopoietin-related protein 4 protein 20100506 {GO:0005515=IPI, GO:0004857=ISS, GO:0001666=NAS, GO:0043066=IDA, GO:0005578=IEA, GO:0070328=ISS, GO:0005576=TAS, GO:0044281=TAS, GO:0001525=IEA, GO:0005615=IDA, GO:0030154=IEA, GO:0045766=TAS, GO:0051005=IDA, GO:0051260=IEA, GO:0044255=TAS} angiogenesis, cell differentiation, cellular lipid metabolic process, negative regulation of apoptotic process, negative regulation of lipoprotein lipase activity, positive regulation of angiogenesis, protein homooligomerization, response to hypoxia, small molecule metabolic process, triglyceride homeostasis extracellular region, extracellular space, proteinaceous extracellular matrix enzyme inhibitor activity, protein binding Human UniProtKB:Q9Z1P8 ANGPTL7 PINC UniProtKB {GO:0005576=GO_REF:0000039, GO:0006979=PMID:8026862} O43827 Angiopoietin-related protein 7 protein 20030904 {GO:0005576=IEA, GO:0006979=TAS} response to oxidative stress extracellular region Human ANK1 BHF-UCL UniProtKB {GO:0005515=PMID:379653, GO:0005886=PMID:379653, GO:0072661=PMID:18768923, GO:0006887=PMID:1833445, GO:0005829=Reactome:REACT_22248, GO:0016323=PMID:12409278, GO:0007411=Reactome:REACT_18266, GO:0048821=GO_REF:0000019, GO:0007010=PMID:9430667, GO:0051117=PMID:8159688, GO:0005856=PMID:1833445, GO:0008093=PMID:379653, GO:0030507=PMID:8159688, GO:0014731=PMID:379653, GO:0031430=GO_REF:0000039, GO:0045199=PMID:11427698, GO:0015672=GO_REF:0000019, GO:0006888=PMID:18768923, GO:0007165=GO_REF:0000002, GO:0016529=GO_REF:0000039, GO:0006779=GO_REF:0000019, GO:0005198=PMID:9430667, GO:0005200=PMID:8640229, GO:0030863=GO_REF:0000019, GO:0019899=PMID:21177872} P16157 Ankyrin-1 protein 20120607 {GO:0005515=IPI, GO:0005886=IDA, GO:0072661=IMP, GO:0006887=NAS, GO:0005829=TAS, GO:0016323=NAS, GO:0007411=TAS, GO:0048821=IEA, GO:0007010=NAS, GO:0051117=IPI, GO:0005856=NAS, GO:0008093=IDA, GO:0030507=IPI, GO:0014731=IDA, GO:0031430=IEA, GO:0045199=TAS, GO:0015672=IEA, GO:0006888=IDA, GO:0007165=IEA, GO:0016529=IEA, GO:0006779=IEA, GO:0005198=NAS, GO:0005200=TAS, GO:0030863=IEA, GO:0019899=IPI} ER to Golgi vesicle-mediated transport, axon guidance, cytoskeleton organization, erythrocyte development, exocytosis, maintenance of epithelial cell apical/basal polarity, monovalent inorganic cation transport, porphyrin-containing compound biosynthetic process, protein targeting to plasma membrane, signal transduction M band, basolateral plasma membrane, cortical cytoskeleton, cytoskeleton, cytosol, plasma membrane, sarcoplasmic reticulum, spectrin-associated cytoskeleton ATPase binding, cytoskeletal adaptor activity, enzyme binding, protein binding, spectrin binding, structural constituent of cytoskeleton, structural molecule activity Human ANK2 BHF-UCL UniProtKB {GO:0005515=PMID:21859974, GO:0030018=GO_REF:0000024, GO:0003283=PMID:18832177, GO:0051928=GO_REF:0000024, GO:0043268=GO_REF:0000019, GO:0015459=GO_REF:0000019, GO:0086070=PMID:21859974, GO:0060307=PMID:18832177, GO:2001259=GO_REF:0000019, GO:0060048=GO_REF:0000019, GO:0086066=GO_REF:0000024, GO:0007411=Reactome:REACT_18266, GO:0045211=GO_REF:0000039, GO:0051924=PMID:12571597, GO:0051117=GO_REF:0000019, GO:0030674=GO_REF:0000019, GO:0005856=GO_REF:0000039, GO:0086004=PMID:17242276, GO:0086005=PMID:17242276, GO:0019901=PMID:18782775, GO:0030507=PMID:15262991, GO:0031430=GO_REF:0000019, GO:0033292=GO_REF:0000019, GO:0044325=PMID:21859974, GO:0002027=PMID:18832177, GO:0005887=GO_REF:0000019, GO:1901018=GO_REF:0000019, GO:0055117=PMID:15178757, GO:0043034=GO_REF:0000019, GO:0086014=PMID:21859974, GO:0019899=PMID:21177872, GO:0031672=GO_REF:0000024, GO:0086015=GO_REF:0000024, GO:0048471=GO_REF:0000019, GO:1901021=GO_REF:0000019, GO:0005886=GO_REF:0000024, GO:0072661=GO_REF:0000019, GO:0070296=PMID:19098452, GO:0086091=PMID:21859974, GO:0005829=Reactome:REACT_22229, GO:0016323=PMID:15611082, GO:0016324=GO_REF:0000039, GO:0031647=PMID:18832177, GO:0014704=GO_REF:0000019, GO:0086046=PMID:19098452, GO:0033365=PMID:15178757, GO:0006874=GO_REF:0000024, GO:0010882=PMID:12571597, GO:0050821=GO_REF:0000019, GO:0010881=PMID:21859974, GO:0030315=GO_REF:0000019, GO:0070972=PMID:15178757, GO:0072659=GO_REF:0000024, GO:0010628=GO_REF:0000019, GO:0007165=GO_REF:0000002, GO:0034394=GO_REF:0000024} Q01484 Ankyrin-2 protein 20120608 {GO:0005515=IPI, GO:0030018=ISS, GO:0003283=IMP, GO:0051928=ISS, GO:0043268=IEA, GO:0015459=IEA, GO:0086070=IMP, GO:0060307=IMP, GO:2001259=IEA, GO:0060048=IEA, GO:0086066=ISS, GO:0007411=TAS, GO:0045211=IEA, GO:0051924=IGI, GO:0051117=IEA, GO:0030674=IEA, GO:0005856=IEA, GO:0086004=IGI, GO:0086005=IMP, GO:0019901=IPI, GO:0030507=IPI, GO:0031430=IEA, GO:0033292=IEA, GO:0044325=IPI, GO:0002027=IMP, GO:0005887=IEA, GO:1901018=IEA, GO:0055117=IMP, GO:0043034=IEA, GO:0086014=IMP, GO:0019899=IPI, GO:0031672=ISS, GO:0086015=ISS, GO:0048471=IEA, GO:1901021=IEA, GO:0005886=ISS, GO:0072661=IEA, GO:0070296=TAS, GO:0086091=IMP, GO:0005829=TAS, GO:0016323=IDA, GO:0016324=IEA, GO:0031647=IC, GO:0014704=IEA, GO:0086046=TAS, GO:0033365=IGI, GO:0006874=ISS, GO:0010882=IMP, GO:0050821=IEA, GO:0010881=ISS, GO:0030315=IEA, GO:0070972=IGI, GO:0072659=ISS, GO:0010628=IEA, GO:0007165=IEA, GO:0034394=ISS} SA node cell to atrial cardiac muscle cell communication, T-tubule organization, atrial cardiac muscle cell to AV node cell communication, atrial septum development, axon guidance, cardiac muscle contraction, cellular calcium ion homeostasis, membrane depolarization involved in regulation of SA node cell action potential, positive regulation of calcium ion transmembrane transporter activity, positive regulation of calcium ion transport, positive regulation of cation channel activity, positive regulation of gene expression, positive regulation of potassium ion transmembrane transporter activity, positive regulation of potassium ion transport, protein localization to cell surface, protein localization to endoplasmic reticulum, protein localization to organelle, protein localization to plasma membrane, protein stabilization, protein targeting to plasma membrane, regulation of SA node cell action potential, regulation of atrial cardiac muscle cell action potential, regulation of calcium ion transport, regulation of cardiac muscle cell contraction, regulation of cardiac muscle contraction, regulation of cardiac muscle contraction by calcium ion signaling, regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion, regulation of heart rate, regulation of heart rate by cardiac conduction, regulation of protein stability, regulation of ventricular cardiac muscle cell action potential, regulation of ventricular cardiac muscle cell membrane repolarization, sarcoplasmic reticulum calcium ion transport, signal transduction A band, M band, T-tubule, Z disc, apical plasma membrane, basolateral plasma membrane, costamere, cytoskeleton, cytosol, integral to plasma membrane, intercalated disc, perinuclear region of cytoplasm, plasma membrane, postsynaptic membrane ATPase binding, enzyme binding, ion channel binding, potassium channel regulator activity, protein binding, protein binding, bridging, protein kinase binding, spectrin binding Human UniProtKB:Q8C8R3 ANK3 BHF-UCL UniProtKB {GO:0005515=PMID:15611082, GO:0008092=PMID:21223964, GO:0007009=PMID:17620337, GO:0072660=PMID:17620337, GO:0005886=GO_REF:0000024, GO:2000651=PMID:18180363, GO:0043001=PMID:17620337, GO:0072661=GO_REF:0000019, GO:0045202=GO_REF:0000019, GO:0007409=GO_REF:0000024, GO:0043266=GO_REF:0000024, GO:0005764=GO_REF:0000039, GO:0019228=GO_REF:0000024, GO:0045184=PMID:15611082, GO:0043194=GO_REF:0000024, GO:0016323=PMID:15611082, GO:0009925=PMID:21223964, GO:0014704=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0045211=GO_REF:0000039, GO:0030674=GO_REF:0000024, GO:0045296=GO_REF:0000024, GO:0009986=PMID:21223964, GO:0000281=PMID:17620337, GO:0030507=GO_REF:0000024, GO:0014731=GO_REF:0000024, GO:0044325=GO_REF:0000024, GO:0042383=PMID:21223964, GO:0010628=PMID:18180363, GO:0007165=GO_REF:0000002, GO:0033268=GO_REF:0000024, GO:0050808=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0043034=PMID:21223964, GO:0005200=PMID:17620337} Q12955 Ankyrin-3 protein 20120607 {GO:0005515=IPI, GO:0008092=ISS, GO:0007009=IMP, GO:0072660=IGI, GO:0005886=ISS, GO:2000651=ISS, GO:0043001=IMP, GO:0072661=IEA, GO:0045202=IEA, GO:0007409=ISS, GO:0043266=ISS, GO:0005764=IEA, GO:0019228=ISS, GO:0045184=IMP, GO:0043194=ISS, GO:0016323=IDA, GO:0009925=IDA, GO:0014704=IEA, GO:0007411=IEA, GO:0045211=IEA, GO:0030674=ISS, GO:0045296=ISS, GO:0009986=ISS, GO:0000281=IMP, GO:0030507=ISS, GO:0014731=ISS, GO:0044325=ISS, GO:0042383=IDA, GO:0010628=ISS, GO:0007165=IEA, GO:0033268=ISS, GO:0050808=IEA, GO:0016020=IEA, GO:0043034=TAS, GO:0005200=IMP} Golgi to plasma membrane protein transport, axon guidance, axonogenesis, cytokinesis after mitosis, establishment of protein localization, maintenance of protein location in plasma membrane, plasma membrane organization, positive regulation of gene expression, positive regulation of sodium ion transmembrane transporter activity, protein targeting to plasma membrane, regulation of action potential in neuron, regulation of potassium ion transport, signal transduction, synapse organization axon initial segment, basal plasma membrane, basolateral plasma membrane, cell surface, costamere, intercalated disc, lysosome, membrane, node of Ranvier, plasma membrane, postsynaptic membrane, sarcolemma, spectrin-associated cytoskeleton, synapse cadherin binding, cytoskeletal protein binding, ion channel binding, protein binding, protein binding, bridging, spectrin binding, structural constituent of cytoskeleton Human UniProtKB:G5E8K5 ANKAR UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q7Z5J8 Ankyrin and armadillo repeat-containing protein protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 ANKFY1 HPA UniProtKB {GO:0005515=PMID:20562859, GO:0046872=GO_REF:0000037, GO:0010008=GO_REF:0000024, GO:0043231=GO_REF:0000052} Q9P2R3 Ankyrin repeat and FYVE domain-containing protein 1 protein 20101115 {GO:0005515=IPI, GO:0046872=IEA, GO:0010008=ISS, GO:0043231=IDA} endosome membrane, intracellular membrane-bounded organelle metal ion binding, protein binding Human ANKH GOC UniProtKB {GO:0001501=PMID:10894769, GO:0030500=GO_REF:0000024, GO:0005886=GO_REF:0000024, GO:0005887=GO_REF:0000024, GO:0019867=PMID:11326272, GO:0015114=GO_REF:0000002, GO:0007626=PMID:10894769, GO:0005315=PMID:11326272, GO:0016021=PMID:11326272, GO:0030504=PMID:11326272, GO:0030505=PMID:11326272} Q9HCJ1 Progressive ankylosis protein homolog protein 20130413 {GO:0001501=NAS, GO:0030500=ISS, GO:0005886=ISS, GO:0005887=ISS, GO:0019867=TAS, GO:0015114=IEA, GO:0007626=NAS, GO:0005315=IDA, GO:0016021=IDA, GO:0030504=IDA, GO:0030505=IDA} inorganic diphosphate transport, locomotory behavior, regulation of bone mineralization, skeletal system development integral to membrane, integral to plasma membrane, outer membrane, plasma membrane inorganic diphosphate transmembrane transporter activity, inorganic phosphate transmembrane transporter activity, phosphate ion transmembrane transporter activity Human ANKHD1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q8IWZ3 Ankyrin repeat and KH domain-containing protein 1 protein 20100326 {GO:0005737=IDA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA} cytoplasm, nucleolus, nucleus RNA binding Human ANKIB1 IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0008270=GO_REF:0000002} Q9P2G1 Ankyrin repeat and IBR domain-containing protein 1 protein 20130415 {GO:0005515=IPI, GO:0008270=IEA} protein binding, zinc ion binding Human UniProtKB:P22736 ANKLE1 null null {} null null null null {} null null null ANKLE2 HPA UniProtKB {GO:0005515=PMID:22770216, GO:0007084=Reactome:REACT_160113, GO:0035307=PMID:22770216, GO:0008601=PMID:22770216, GO:0030176=PMID:22770216, GO:0042326=PMID:22770216, GO:0005737=GO_REF:0000052, GO:0050790=PMID:22770216, GO:0000087=Reactome:REACT_910, GO:0005789=Reactome:REACT_160159, GO:0000278=Reactome:REACT_152, GO:0051721=PMID:22770216, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q86XL3 Ankyrin repeat and LEM domain-containing protein 2 protein 20080818 {GO:0005515=IPI, GO:0007084=TAS, GO:0035307=IDA, GO:0008601=TAS, GO:0030176=IDA, GO:0042326=IDA, GO:0005737=IDA, GO:0050790=TAS, GO:0000087=TAS, GO:0005789=TAS, GO:0000278=TAS, GO:0051721=IDA, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, cell division, mitotic anaphase, mitotic cell cycle, mitotic nuclear envelope reassembly, negative regulation of phosphorylation, positive regulation of protein dephosphorylation, regulation of catalytic activity cytoplasm, endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane protein binding, protein phosphatase 2A binding, protein phosphatase type 2A regulator activity Human ANKMY2 UniProtKB UniProtKB {GO:0005929=GO_REF:0000039, GO:0008270=GO_REF:0000002} Q8IV38 Ankyrin repeat and MYND domain-containing protein 2 protein 20130413 {GO:0005929=IEA, GO:0008270=IEA} cilium zinc ion binding Human UniProtKB-SubCell:SL-0066 ANKRA2 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0016020=PMID:11095640, GO:0042826=GO_REF:0000019, GO:0030169=PMID:11095640, GO:0005634=GO_REF:0000019, GO:0005856=GO_REF:0000039, GO:0005829=PMID:11095640} Q9H9E1 Ankyrin repeat family A protein 2 protein 20061026 {GO:0008150=ND, GO:0016020=IDA, GO:0042826=IEA, GO:0030169=IDA, GO:0005634=IEA, GO:0005856=IEA, GO:0005829=IDA} biological_process cytoskeleton, cytosol, membrane, nucleus histone deacetylase binding, low-density lipoprotein particle binding Human ANKRD1 GOC UniProtKB {GO:0005515=PMID:19608030, GO:0042826=PMID:20599664, GO:0071560=PMID:11139470, GO:0005634=PMID:19608030, GO:0044281=Reactome:REACT_111217, GO:0005829=PMID:19608030, GO:0002039=PMID:20599664, GO:0005737=PMID:12054667, GO:0045944=PMID:20599664, GO:0071356=PMID:7730328, GO:0001085=PMID:20599664, GO:0055008=PMID:19608030, GO:0044255=Reactome:REACT_22279, GO:0005667=GO_REF:0000019, GO:0001105=PMID:20599664, GO:0043065=PMID:15805281, GO:0003714=PMID:20599664, GO:0045214=PMID:11309420, GO:0071456=GO_REF:0000019, GO:0035994=PMID:19608030, GO:0070412=PMID:20599664, GO:0000122=GO_REF:0000019, GO:0035690=GO_REF:0000019, GO:0003677=PMID:7730328, GO:0031432=PMID:14583192, GO:0071407=GO_REF:0000019, GO:0071222=PMID:7730328, GO:0010976=GO_REF:0000019, GO:0071347=PMID:7730328, GO:0043517=PMID:20599664, GO:2000279=PMID:11139470, GO:0005654=Reactome:REACT_115878, GO:0031674=PMID:19525294} Q15327 Ankyrin repeat domain-containing protein 1 protein 20130413 {GO:0005515=IPI, GO:0042826=IPI, GO:0071560=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0005829=IDA, GO:0002039=IPI, GO:0005737=IDA, GO:0045944=IDA, GO:0071356=IDA, GO:0001085=IPI, GO:0055008=IMP, GO:0044255=TAS, GO:0005667=IEA, GO:0001105=IDA, GO:0043065=IMP, GO:0003714=TAS, GO:0045214=NAS, GO:0071456=IEA, GO:0035994=IMP, GO:0070412=IPI, GO:0000122=IEA, GO:0035690=IEA, GO:0003677=IDA, GO:0031432=IPI, GO:0071407=IEA, GO:0071222=IDA, GO:0010976=IEA, GO:0071347=IDA, GO:0043517=IDA, GO:2000279=IMP, GO:0005654=TAS, GO:0031674=ISS} cardiac muscle tissue morphogenesis, cellular lipid metabolic process, cellular response to drug, cellular response to hypoxia, cellular response to interleukin-1, cellular response to lipopolysaccharide, cellular response to organic cyclic compound, cellular response to transforming growth factor beta stimulus, cellular response to tumor necrosis factor, negative regulation of DNA biosynthetic process, negative regulation of transcription from RNA polymerase II promoter, positive regulation of DNA damage response, signal transduction by p53 class mediator, positive regulation of apoptotic process, positive regulation of neuron projection development, positive regulation of transcription from RNA polymerase II promoter, response to muscle stretch, sarcomere organization, small molecule metabolic process I band, cytoplasm, cytosol, nucleoplasm, nucleus, transcription factor complex DNA binding, R-SMAD binding, RNA polymerase II transcription coactivator activity, RNA polymerase II transcription factor binding, histone deacetylase binding, p53 binding, protein binding, titin binding, transcription corepressor activity Human ANKRD10 null null {} null null null null {} null null null ANKRD11 MGI UniProtKB {GO:0060348=GO_REF:0000019, GO:0060325=PMID:21782149, GO:0035264=GO_REF:0000019, GO:0001894=GO_REF:0000019, GO:0048705=PMID:21782149, GO:0042475=PMID:21782149, GO:0005634=PMID:21782149, GO:0001701=GO_REF:0000019} Q6UB99 Ankyrin repeat domain-containing protein 11 protein 20121106 {GO:0060348=IEA, GO:0060325=IMP, GO:0035264=IEA, GO:0001894=IEA, GO:0048705=IMP, GO:0042475=IMP, GO:0005634=IDA, GO:0001701=IEA} bone development, face morphogenesis, in utero embryonic development, multicellular organism growth, odontogenesis of dentin-containing tooth, skeletal system morphogenesis, tissue homeostasis nucleus Human ANKRD12 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q6UB98 Ankyrin repeat domain-containing protein 12 protein 20110516 {GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA} cytoplasm, nucleolus, nucleus Human ANKRD13A null null {} null null null null {} null null null ANKRD13B null null {} null null null null {} null null null ANKRD13C BHF-UCL UniProtKB {GO:0010869=PMID:20959461, GO:0048471=PMID:20959461, GO:0005783=PMID:20959461, GO:0005102=PMID:20959461, GO:0005789=GO_REF:0000039, GO:2000209=PMID:20959461, GO:0006621=PMID:20959461} Q8N6S4 Ankyrin repeat domain-containing protein 13C protein 20101028 {GO:0010869=IDA, GO:0048471=IDA, GO:0005783=IDA, GO:0005102=IPI, GO:0005789=IEA, GO:2000209=IDA, GO:0006621=IMP} protein retention in ER lumen, regulation of anoikis, regulation of receptor biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, perinuclear region of cytoplasm receptor binding Human ANKRD13D null null {} null null null null {} null null null ANKRD17 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0051151=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0001955=GO_REF:0000019} O75179 Ankyrin repeat domain-containing protein 17 protein 20111111 {GO:0005737=IDA, GO:0051151=IEA, GO:0019048=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0001955=IEA} blood vessel maturation, negative regulation of smooth muscle cell differentiation, virus-host interaction cytoplasm, nucleus RNA binding Human ANKRD18A null null {} null null null null {} null null null ANKRD18B null null {} null null null null {} null null null ANKRD2 HPA UniProtKB {GO:0007517=PMID:11444853, GO:0006936=PMID:10873377, GO:0008307=PMID:11444853, GO:0031674=GO_REF:0000019, GO:0031432=GO_REF:0000019, GO:0043231=GO_REF:0000052} Q9GZV1 Ankyrin repeat domain-containing protein 2 protein 20111111 {GO:0007517=NAS, GO:0006936=NAS, GO:0008307=NAS, GO:0031674=IEA, GO:0031432=IEA, GO:0043231=IDA} muscle contraction, muscle organ development I band, intracellular membrane-bounded organelle structural constituent of muscle, titin binding Human ANKRD22 null null {} null null null null {} null null null ANKRD23 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0006631=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0015629=GO_REF:0000052, GO:0031432=PMID:14583192, GO:0031674=GO_REF:0000019} Q86SG2 Ankyrin repeat domain-containing protein 23 protein 20110516 {GO:0005737=IDA, GO:0005730=IDA, GO:0006631=IEA, GO:0005634=IDA, GO:0015629=IDA, GO:0031432=IPI, GO:0031674=IEA} fatty acid metabolic process I band, actin cytoskeleton, cytoplasm, nucleolus, nucleus titin binding Human ANKRD24 null null {} null null null null {} null null null ANKRD26 UniProtKB UniProtKB {GO:0005813=PMID:21399614} Q9UPS8 Ankyrin repeat domain-containing protein 26 protein 20110517 {GO:0005813=IDA} centrosome Human ANKRD27 IntAct UniProtKB {GO:0005515=PMID:22705394, GO:0005085=PMID:16525121, GO:0045022=PMID:16525121, GO:0005764=GO_REF:0000054, GO:0005769=PMID:16525121, GO:0005096=GO_REF:0000037} Q96NW4 Ankyrin repeat domain-containing protein 27 protein 20130415 {GO:0005515=IPI, GO:0005085=IDA, GO:0045022=IDA, GO:0005764=IDA, GO:0005769=IDA, GO:0005096=IEA} early endosome to late endosome transport early endosome, lysosome GTPase activator activity, guanyl-nucleotide exchange factor activity, protein binding Human UniProtKB:Q13439 ANKRD28 IntAct UniProtKB {GO:0005515=PMID:18186651, GO:0005654=GO_REF:0000039} O15084 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A protein 20130415 {GO:0005515=IPI, GO:0005654=IEA} nucleoplasm protein binding Human UniProtKB:Q9UPN7 ANKRD30A UniProtKB UniProtKB {GO:0006355=PMID:11280766, GO:0003700=PMID:11280766, GO:0005634=PMID:11280766, GO:0003677=PMID:11280766} Q9BXX3 Ankyrin repeat domain-containing protein 30A protein 20010919 {GO:0006355=NAS, GO:0003700=NAS, GO:0005634=NAS, GO:0003677=NAS} regulation of transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity Human ANKRD32 ENSEMBL UniProtKB {GO:0005813=GO_REF:0000019, GO:0005634=GO_REF:0000019} Q9BQI6 Ankyrin repeat domain-containing protein 32 protein 20130413 {GO:0005813=IEA, GO:0005634=IEA} centrosome, nucleus Human Ensembl:ENSMUSP00000118312 ANKRD34A HPA UniProtKB {GO:0005737=GO_REF:0000052} Q69YU3 Ankyrin repeat domain-containing protein 34A protein 20101115 {GO:0005737=IDA} cytoplasm Human ANKRD35 null null {} null null null null {} null null null ANKRD36C UniProtKB UniProtKB {GO:0008200=PMID:8608414} Q5JPF3 Ankyrin repeat domain-containing protein 36C protein 20090723 {GO:0008200=NAS} ion channel inhibitor activity Human ANKRD37 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039} Q7Z713 Ankyrin repeat domain-containing protein 37 protein 20130413 {GO:0005737=IEA, GO:0005634=IEA} cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 ANKRD39 BHF-UCL UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q53RE8 Ankyrin repeat domain-containing protein 39 protein 20120523 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human ANKRD40 BHF-UCL UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q6AI12 Ankyrin repeat domain-containing protein 40 protein 20120523 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human ANKRD42 ENSEMBL UniProtKB {GO:1900017=GO_REF:0000019, GO:0051092=GO_REF:0000019, GO:0051059=GO_REF:0000019, GO:0005634=GO_REF:0000019} Q8N9B4 Ankyrin repeat domain-containing protein 42 protein 20130413 {GO:1900017=IEA, GO:0051092=IEA, GO:0051059=IEA, GO:0005634=IEA} positive regulation of NF-kappaB transcription factor activity, positive regulation of cytokine production involved in inflammatory response nucleus NF-kappaB binding Human Ensembl:ENSMUSP00000113767 ANKRD44 null null {} null null null null {} null null null ANKRD45 BHF-UCL UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q5TZF3 Ankyrin repeat domain-containing protein 45 protein 20120523 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human ANKRD46 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q86W74 Ankyrin repeat domain-containing protein 46 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 ANKRD50 null null {} null null null null {} null null null ANKRD52 null null {} null null null null {} null null null ANKRD53 null null {} null null null null {} null null null ANKRD55 null null {} null null null null {} null null null ANKRD6 ENSEMBL UniProtKB {GO:0005737=GO_REF:0000019, GO:2000096=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0090090=GO_REF:0000019} Q9Y2G4 Ankyrin repeat domain-containing protein 6 protein 20130413 {GO:0005737=IEA, GO:2000096=IEA, GO:0005634=IEA, GO:0090090=IEA} negative regulation of canonical Wnt receptor signaling pathway, positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway cytoplasm, nucleus Human Ensembl:ENSMUSP00000041300 ANKRD7 PINC UniProtKB {GO:0005634=GO_REF:0000019, GO:0008584=PMID:8812458} Q92527 Ankyrin repeat domain-containing protein 7 protein 20030904 {GO:0005634=IEA, GO:0008584=TAS} male gonad development nucleus Human ANKS1A HPA UniProtKB {GO:0016322=GO_REF:0000024, GO:0043005=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0048013=GO_REF:0000024, GO:0046875=GO_REF:0000019, GO:0006929=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q92625 Ankyrin repeat and SAM domain-containing protein 1A protein 20110516 {GO:0016322=ISS, GO:0043005=ISS, GO:0005737=IDA, GO:0048013=ISS, GO:0046875=IEA, GO:0006929=ISS, GO:0005730=IDA, GO:0005634=IDA} ephrin receptor signaling pathway, neuron remodeling, substrate-dependent cell migration cytoplasm, neuron projection, nucleolus, nucleus ephrin receptor binding Human ANKS1B UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0015030=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0046875=PMID:17875921, GO:0005886=GO_REF:0000037, GO:0045211=GO_REF:0000037, GO:0014069=GO_REF:0000039} Q7Z6G8 Ankyrin repeat and sterile alpha motif domain-containing protein 1B protein 20110826 {GO:0005737=IEA, GO:0015030=IEA, GO:0030054=IEA, GO:0046875=IPI, GO:0005886=IEA, GO:0045211=IEA, GO:0014069=IEA} Cajal body, cell junction, cytoplasm, plasma membrane, postsynaptic density, postsynaptic membrane ephrin receptor binding Human UniProtKB:O09127 ANKS3 null null {} null null null null {} null null null ANKS4B ENSEMBL UniProtKB {GO:0005886=GO_REF:0000019} Q8N8V4 Ankyrin repeat and SAM domain-containing protein 4B protein 20130413 {GO:0005886=IEA} plasma membrane Human Ensembl:ENSMUSP00000033201 ANKS6 ENSEMBL UniProtKB {GO:0005737=GO_REF:0000019, GO:0042803=GO_REF:0000019} Q68DC2 Ankyrin repeat and SAM domain-containing protein 6 protein 20130413 {GO:0005737=IEA, GO:0042803=IEA} cytoplasm protein homodimerization activity Human Ensembl:ENSRNOP00000056754 ANKZF1 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0008270=GO_REF:0000002} Q9H8Y5 Ankyrin repeat and zinc finger domain-containing protein 1 protein 20130415 {GO:0005515=IPI, GO:0008270=IEA} protein binding, zinc ion binding Human UniProtKB:Q9Q2G4 ANLN PINC UniProtKB {GO:0000910=PMID:10931866, GO:0005826=PMID:10931866, GO:0007067=GO_REF:0000037, GO:0000921=PMID:10931866, GO:0005543=GO_REF:0000002, GO:0007096=PMID:10931866, GO:0003779=PMID:10931866, GO:0005634=GO_REF:0000039, GO:0015629=PMID:10931866} Q9NQW6 Actin-binding protein anillin protein 20061106 {GO:0000910=IDA, GO:0005826=IDA, GO:0007067=IEA, GO:0000921=TAS, GO:0005543=IEA, GO:0007096=TAS, GO:0003779=IDA, GO:0005634=IEA, GO:0015629=IDA} cytokinesis, mitosis, regulation of exit from mitosis, septin ring assembly actin cytoskeleton, actomyosin contractile ring, nucleus actin binding, phospholipid binding Human ANO1 Reactome UniProtKB {GO:0005515=PMID:22178883, GO:0006821=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_160277, GO:0034707=GO_REF:0000037, GO:0005229=PMID:21984732, GO:0007275=GO_REF:0000037, GO:0016021=GO_REF:0000038, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000038} Q5XXA6 Anoctamin-1 protein 20130301 {GO:0005515=IPI, GO:0006821=ISS, GO:0005737=IEA, GO:0034220=TAS, GO:0005886=TAS, GO:0034707=IEA, GO:0005229=IDA, GO:0007275=IEA, GO:0016021=IEA, GO:0055085=TAS, GO:0005254=IEA} chloride transport, ion transmembrane transport, multicellular organismal development, transmembrane transport chloride channel complex, cytoplasm, integral to membrane, plasma membrane chloride channel activity, intracellular calcium activated chloride channel activity, protein binding Human ANO10 Reactome UniProtKB {GO:0005622=PMID:22075693, GO:0008219=GO_REF:0000037, GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_160277, GO:0034707=GO_REF:0000038, GO:0005229=PMID:21984732, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000038} Q9NW15 Anoctamin-10 protein 20130301 {GO:0005622=IDA, GO:0008219=IEA, GO:0034220=TAS, GO:0005886=TAS, GO:0034707=IEA, GO:0005229=IDA, GO:0016021=IEA, GO:0055085=TAS, GO:0005254=IEA} cell death, ion transmembrane transport, transmembrane transport chloride channel complex, integral to membrane, intracellular, plasma membrane chloride channel activity, intracellular calcium activated chloride channel activity Human ANO2 HPA UniProtKB {GO:0034220=Reactome:REACT_25300, GO:0005886=GO_REF:0000052, GO:0034707=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005229=PMID:21984732, GO:0005634=GO_REF:0000052, GO:0016021=GO_REF:0000038, GO:0055085=Reactome:REACT_15518} Q9NQ90 Anoctamin-2 protein 20110516 {GO:0034220=TAS, GO:0005886=IDA, GO:0034707=IEA, GO:0005730=IDA, GO:0005229=IDA, GO:0005634=IDA, GO:0016021=IEA, GO:0055085=TAS} ion transmembrane transport, transmembrane transport chloride channel complex, integral to membrane, nucleolus, nucleus, plasma membrane intracellular calcium activated chloride channel activity Human ANO5 Reactome UniProtKB {GO:0005622=PMID:22075693, GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_160277, GO:0005789=GO_REF:0000039, GO:0005229=PMID:22075693, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_15518} Q75V66 Anoctamin-5 protein 20130301 {GO:0005622=IDA, GO:0034220=TAS, GO:0005886=TAS, GO:0005789=IEA, GO:0005229=IDA, GO:0016021=IEA, GO:0055085=TAS} ion transmembrane transport, transmembrane transport endoplasmic reticulum membrane, integral to membrane, intracellular, plasma membrane intracellular calcium activated chloride channel activity Human ANO6 Reactome UniProtKB {GO:0017121=GO_REF:0000024, GO:0005244=GO_REF:0000024, GO:0005886=Reactome:REACT_160277, GO:0034707=GO_REF:0000037, GO:0002543=PMID:21107324, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000038, GO:0097045=PMID:21107324, GO:0005622=PMID:22075693, GO:0034220=Reactome:REACT_25300, GO:0007596=GO_REF:0000024, GO:0005229=PMID:21984732, GO:0016021=GO_REF:0000038, GO:0005227=GO_REF:0000024} Q4KMQ2 Anoctamin-6 protein 20130301 {GO:0017121=ISS, GO:0005244=ISS, GO:0005886=TAS, GO:0034707=IEA, GO:0002543=IMP, GO:0055085=TAS, GO:0005254=IEA, GO:0097045=IMP, GO:0005622=IDA, GO:0034220=TAS, GO:0007596=ISS, GO:0005229=IDA, GO:0016021=IEA, GO:0005227=ISS} activation of blood coagulation via clotting cascade, blood coagulation, ion transmembrane transport, phosphatidylserine exposure on blood platelet, phospholipid scrambling, transmembrane transport chloride channel complex, integral to membrane, intracellular, plasma membrane calcium activated cation channel activity, chloride channel activity, intracellular calcium activated chloride channel activity, voltage-gated ion channel activity Human ANO8 Reactome UniProtKB {GO:0005622=GO_REF:0000019, GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_160277, GO:0005229=PMID:21984732, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_15518} Q9HCE9 Anoctamin-8 protein 20130301 {GO:0005622=IEA, GO:0034220=TAS, GO:0005886=TAS, GO:0005229=IDA, GO:0016021=IEA, GO:0055085=TAS} ion transmembrane transport, transmembrane transport integral to membrane, intracellular, plasma membrane intracellular calcium activated chloride channel activity Human ANP32A IntAct UniProtKB {GO:0005515=PMID:16169070, GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000037, GO:0048471=PMID:12524539, GO:0016070=Reactome:REACT_21257, GO:0005783=PMID:12524539, GO:0016071=Reactome:REACT_20605, GO:0005634=PMID:11729309, GO:0006351=GO_REF:0000037, GO:0006913=PMID:11729309, GO:0035556=PMID:8192856, GO:0005737=PMID:12524539, GO:0005654=Reactome:REACT_25286} P39687 Acidic leucine-rich nuclear phosphoprotein 32 family member A protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0006355=IEA, GO:0048471=IDA, GO:0016070=TAS, GO:0005783=IDA, GO:0016071=TAS, GO:0005634=IDA, GO:0006351=IEA, GO:0006913=IDA, GO:0035556=TAS, GO:0005737=IDA, GO:0005654=TAS} RNA metabolic process, gene expression, intracellular signal transduction, mRNA metabolic process, nucleocytoplasmic transport, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, endoplasmic reticulum, nucleoplasm, nucleus, perinuclear region of cytoplasm protein binding Human UniProtKB:O15169 ANP32B UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039} Q92688 Acidic leucine-rich nuclear phosphoprotein 32 family member B protein 20130413 {GO:0005737=IEA, GO:0005634=IEA} cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 ANP32D null null {} null null null null {} null null null ANP32E LIFEdb UniProtKB {GO:0016023=GO_REF:0000024, GO:0005634=GO_REF:0000054, GO:0019212=GO_REF:0000024} Q9BTT0 Acidic leucine-rich nuclear phosphoprotein 32 family member E protein 20100607 {GO:0016023=ISS, GO:0005634=IDA, GO:0019212=ISS} cytoplasmic membrane-bounded vesicle, nucleus phosphatase inhibitor activity Human ANPEP Reactome UniProtKB {GO:0005793=PMID:15308636, GO:0002003=Reactome:REACT_147707, GO:0001525=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0005829=GO_REF:0000039, GO:0005887=PMID:2564851, GO:0004177=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0004872=PMID:1350662, GO:0044267=Reactome:REACT_17015, GO:0009897=GO_REF:0000019, GO:0008237=GO_REF:0000037} P15144 Aminopeptidase N protein 20111129 {GO:0005793=IDA, GO:0002003=TAS, GO:0001525=IEA, GO:0030154=IEA, GO:0005829=IEA, GO:0005887=TAS, GO:0004177=IEA, GO:0019048=IEA, GO:0006508=IEA, GO:0008270=IEA, GO:0004872=TAS, GO:0044267=TAS, GO:0009897=IEA, GO:0008237=IEA} angiogenesis, angiotensin maturation, cell differentiation, cellular protein metabolic process, proteolysis, virus-host interaction cytosol, endoplasmic reticulum-Golgi intermediate compartment, external side of plasma membrane, integral to plasma membrane aminopeptidase activity, metallopeptidase activity, receptor activity, zinc ion binding Human ANTXR1 IntAct UniProtKB {GO:0005515=PMID:16564009, GO:0022414=GO_REF:0000019, GO:0051015=PMID:16762926, GO:0031532=PMID:16762926, GO:0031258=PMID:16762926, GO:0005518=PMID:16762926, GO:0031527=PMID:16762926, GO:0034446=PMID:16762926, GO:0004872=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0004888=PMID:16762926} Q9H6X2 Anthrax toxin receptor 1 protein 20130415 {GO:0005515=IPI, GO:0022414=IEA, GO:0051015=IDA, GO:0031532=IDA, GO:0031258=IDA, GO:0005518=IDA, GO:0031527=IDA, GO:0034446=IDA, GO:0004872=IEA, GO:0016021=IEA, GO:0046872=IEA, GO:0004888=IDA} actin cytoskeleton reorganization, reproductive process, substrate adhesion-dependent cell spreading filopodium membrane, integral to membrane, lamellipodium membrane actin filament binding, collagen binding, metal ion binding, protein binding, receptor activity, transmembrane signaling receptor activity Human UniProtKB:O75581 ANTXR2 IntAct UniProtKB {GO:0005515=PMID:15326297, GO:0022414=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0005576=GO_REF:0000039, GO:0004872=GO_REF:0000002, GO:0016021=GO_REF:0000019, GO:0046872=GO_REF:0000037} P58335 Anthrax toxin receptor 2 protein 20130415 {GO:0005515=IPI, GO:0022414=IEA, GO:0005886=IEA, GO:0005789=IEA, GO:0005576=IEA, GO:0004872=IEA, GO:0016021=IEA, GO:0046872=IEA} reproductive process endoplasmic reticulum membrane, extracellular region, integral to membrane, plasma membrane metal ion binding, protein binding, receptor activity Human UniProtKB:P13423 ANXA1 HPA UniProtKB {GO:0070301=GO_REF:0000019, GO:0046632=GO_REF:0000019, GO:0060206=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0030674=PMID:10908733, GO:0032355=GO_REF:0000019, GO:0033031=GO_REF:0000019, GO:0031966=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0031394=GO_REF:0000019, GO:0002674=GO_REF:0000019, GO:0042063=GO_REF:0000019, GO:0071385=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0005929=GO_REF:0000039, GO:0007049=GO_REF:0000019, GO:0050709=GO_REF:0000019, GO:0030073=GO_REF:0000019, GO:0001780=GO_REF:0000019, GO:0010165=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0043434=GO_REF:0000019, GO:0031340=PMID:2138016, GO:0006928=PMID:10882119, GO:0005634=GO_REF:0000019, GO:0001533=PMID:10908733, GO:0005544=GO_REF:0000002, GO:0016323=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0005543=PMID:2967291, GO:0006954=PMID:10882119, GO:0070555=GO_REF:0000019, GO:0050482=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0004859=GO_REF:0000002, GO:0042493=GO_REF:0000019, GO:0005102=PMID:10882119, GO:0005576=Reactome:REACT_22436, GO:0019834=GO_REF:0000019, GO:0042383=GO_REF:0000019, GO:0007165=PMID:16130169, GO:0018149=PMID:10908733, GO:0005198=PMID:10908733, GO:0030216=PMID:10908733, GO:0031018=GO_REF:0000019, GO:0007166=GO_REF:0000019, GO:0070365=GO_REF:0000019} Q5T3N1 Annexin A1 protein 20081203 {GO:0070301=IEA, GO:0046632=IEA, GO:0060206=IEA, GO:0005615=IEA, GO:0042803=IEA, GO:0042127=IEA, GO:0030674=IDA, GO:0032355=IEA, GO:0033031=IEA, GO:0031966=IEA, GO:0005509=IEA, GO:0031394=IEA, GO:0002674=IEA, GO:0042063=IEA, GO:0071385=IEA, GO:0043234=IEA, GO:0005929=IEA, GO:0007049=IEA, GO:0050709=IEA, GO:0030073=IEA, GO:0001780=IEA, GO:0010165=IEA, GO:0005886=IDA, GO:0043434=IEA, GO:0031340=IDA, GO:0006928=TAS, GO:0005634=IEA, GO:0001533=IDA, GO:0005544=IEA, GO:0016323=IEA, GO:0005737=IDA, GO:0005543=TAS, GO:0006954=TAS, GO:0070555=IEA, GO:0050482=IEA, GO:0043066=IEA, GO:0004859=IEA, GO:0042493=IEA, GO:0005102=TAS, GO:0005576=TAS, GO:0019834=IEA, GO:0042383=IEA, GO:0007165=TAS, GO:0018149=IDA, GO:0005198=IDA, GO:0030216=IDA, GO:0031018=IEA, GO:0007166=IEA, GO:0070365=IEA} alpha-beta T cell differentiation, arachidonic acid secretion, cell cycle, cell surface receptor signaling pathway, cellular component movement, cellular response to glucocorticoid stimulus, cellular response to hydrogen peroxide, endocrine pancreas development, estrous cycle phase, gliogenesis, hepatocyte differentiation, inflammatory response, insulin secretion, keratinocyte differentiation, negative regulation of acute inflammatory response, negative regulation of apoptotic process, negative regulation of protein secretion, neutrophil homeostasis, peptide cross-linking, positive regulation of neutrophil apoptotic process, positive regulation of prostaglandin biosynthetic process, positive regulation of vesicle fusion, regulation of cell proliferation, response to X-ray, response to drug, response to estradiol stimulus, response to interleukin-1, response to peptide hormone stimulus, signal transduction basolateral plasma membrane, cilium, cornified envelope, cytoplasm, extracellular region, extracellular space, mitochondrial membrane, nucleus, plasma membrane, protein complex, sarcolemma calcium ion binding, calcium-dependent phospholipid binding, phospholipase A2 inhibitor activity, phospholipase inhibitor activity, phospholipid binding, protein binding, bridging, protein homodimerization activity, receptor binding, structural molecule activity Human ANXA10 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0005544=GO_REF:0000002, GO:0005509=GO_REF:0000002} Q9UJ72 Annexin A10 protein 20130413 {GO:0005739=IEA, GO:0005544=IEA, GO:0005509=IEA} mitochondrion calcium ion binding, calcium-dependent phospholipid binding Human Ensembl:ENSMUSP00000034052 ANXA11 ENSEMBL UniProtKB {GO:0006909=PMID:9188810, GO:0005515=PMID:9268363, GO:0042470=GO_REF:0000039, GO:0008429=GO_REF:0000019, GO:0005509=GO_REF:0000019, GO:0005819=PMID:12805373, GO:0030496=PMID:15197175, GO:0005635=PMID:12601007, GO:0007109=PMID:15197175, GO:0005544=GO_REF:0000019, GO:0051592=PMID:9188810, GO:0044548=PMID:19724273, GO:0005737=GO_REF:0000019, GO:0007049=GO_REF:0000037, GO:0005654=PMID:7508441, GO:0048306=PMID:11883939} Q5T0G9 Annexin A11 protein 20130413 {GO:0006909=IEP, GO:0005515=IPI, GO:0042470=IEA, GO:0008429=IEA, GO:0005509=IEA, GO:0005819=IDA, GO:0030496=IDA, GO:0005635=IDA, GO:0007109=IMP, GO:0005544=IEA, GO:0051592=IDA, GO:0044548=IPI, GO:0005737=IEA, GO:0007049=IEA, GO:0005654=IDA, GO:0048306=IPI} cell cycle, cytokinesis, completion of separation, phagocytosis, response to calcium ion cytoplasm, melanosome, midbody, nuclear envelope, nucleoplasm, spindle S100 protein binding, calcium ion binding, calcium-dependent phospholipid binding, calcium-dependent protein binding, phosphatidylethanolamine binding, protein binding Human Ensembl:ENSMUSP00000022416 ANXA13 HPA UniProtKB {GO:0005544=GO_REF:0000029, GO:0005886=GO_REF:0000052, GO:0005509=GO_REF:0000002, GO:0030154=PMID:1530946} P27216 Annexin A13 protein 20101115 {GO:0005544=NAS, GO:0005886=IDA, GO:0005509=IEA, GO:0030154=NAS} cell differentiation plasma membrane calcium ion binding, calcium-dependent phospholipid binding Human ANXA2 BHF-UCL UniProtKB {GO:0008092=GO_REF:0000002, GO:0005515=PMID:20706999, GO:0048471=GO_REF:0000019, GO:0005886=PMID:10809787, GO:0031340=PMID:2138016, GO:0005544=PMID:2138016, GO:0035749=GO_REF:0000019, GO:0030199=GO_REF:0000019, GO:0007589=GO_REF:0000019, GO:0043220=GO_REF:0000019, GO:0042470=GO_REF:0000039, GO:0017137=GO_REF:0000019, GO:0004859=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0005546=GO_REF:0000019, GO:0051099=GO_REF:0000019, GO:0030496=PMID:15166316, GO:0001525=PMID:11866539, GO:0005604=GO_REF:0000039, GO:0031012=PMID:22261194, GO:0042383=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0001501=PMID:7961821, GO:0071229=GO_REF:0000019, GO:0042730=GO_REF:0000019, GO:0019897=GO_REF:0000019, GO:0005769=GO_REF:0000019} P07355 Annexin A2 protein 20120228 {GO:0008092=IEA, GO:0005515=IPI, GO:0048471=IEA, GO:0005886=TAS, GO:0031340=IDA, GO:0005544=IDA, GO:0035749=IEA, GO:0030199=IEA, GO:0007589=IEA, GO:0043220=IEA, GO:0042470=IEA, GO:0017137=IEA, GO:0004859=IEA, GO:0005509=IEA, GO:0005546=IEA, GO:0051099=IEA, GO:0030496=IDA, GO:0001525=IEP, GO:0005604=IEA, GO:0031012=ISS, GO:0042383=IEA, GO:0043234=IEA, GO:0001501=TAS, GO:0071229=IEA, GO:0042730=IEA, GO:0019897=IEA, GO:0005769=IEA} angiogenesis, body fluid secretion, cellular response to acid, collagen fibril organization, fibrinolysis, positive regulation of binding, positive regulation of vesicle fusion, skeletal system development Schmidt-Lanterman incisure, basement membrane, early endosome, extracellular matrix, extrinsic to plasma membrane, melanosome, midbody, myelin sheath adaxonal region, perinuclear region of cytoplasm, plasma membrane, protein complex, sarcolemma Rab GTPase binding, calcium ion binding, calcium-dependent phospholipid binding, cytoskeletal protein binding, phosphatidylinositol-4,5-bisphosphate binding, phospholipase inhibitor activity, protein binding colocalizes_with Human UniProtKB:P19620 ANXA3 HPA UniProtKB {GO:0006909=PMID:9497492, GO:0004859=GO_REF:0000002, GO:0005886=PMID:7526843, GO:0043312=PMID:9550422, GO:0005509=GO_REF:0000002, GO:0042581=PMID:7526843, GO:0019834=GO_REF:0000037, GO:0045766=PMID:16236264, GO:0005544=PMID:2138632, GO:0010595=PMID:16236264, GO:0005737=GO_REF:0000052, GO:0051091=PMID:16236264, GO:0016020=PMID:17205602, GO:0030670=PMID:7526843, GO:0042742=PMID:9497492} P12429 Annexin A3 protein 20101115 {GO:0006909=IDA, GO:0004859=IEA, GO:0005886=IDA, GO:0043312=IDA, GO:0005509=IEA, GO:0042581=IDA, GO:0019834=IEA, GO:0045766=IDA, GO:0005544=IDA, GO:0010595=IDA, GO:0005737=IDA, GO:0051091=IDA, GO:0016020=IDA, GO:0030670=IDA, GO:0042742=IDA} defense response to bacterium, neutrophil degranulation, phagocytosis, positive regulation of angiogenesis, positive regulation of endothelial cell migration, positive regulation of sequence-specific DNA binding transcription factor activity cytoplasm, membrane, phagocytic vesicle membrane, plasma membrane, specific granule calcium ion binding, calcium-dependent phospholipid binding, phospholipase A2 inhibitor activity, phospholipase inhibitor activity Human ANXA4 UniProtKB UniProtKB {GO:0005544=GO_REF:0000038, GO:0007165=PMID:16130169, GO:0005737=PMID:16130169, GO:0043066=PMID:16130169, GO:0004859=PMID:2970257, GO:0050819=GO_REF:0000002, GO:0005509=GO_REF:0000002} Q6P452 Annexin protein 20130413 {GO:0005544=IEA, GO:0007165=TAS, GO:0005737=TAS, GO:0043066=TAS, GO:0004859=NAS, GO:0050819=IEA, GO:0005509=IEA} negative regulation of apoptotic process, negative regulation of coagulation, signal transduction cytoplasm calcium ion binding, calcium-dependent phospholipid binding, phospholipase inhibitor activity Human UniProtKB-KW:KW-0111 ANXA5 LIFEdb UniProtKB {GO:0043066=PMID:16130169, GO:0004859=PMID:2967495, GO:0010033=GO_REF:0000019, GO:0043499=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0072563=GO_REF:0000019, GO:0005622=GO_REF:0000054, GO:0005544=PMID:2138016, GO:0007165=PMID:16130169, GO:0050819=GO_REF:0000002, GO:0005737=PMID:16130169, GO:0005543=PMID:2967291, GO:0007596=GO_REF:0000037, GO:0009897=GO_REF:0000019} P08758 Annexin A5 protein 20100607 {GO:0043066=TAS, GO:0004859=TAS, GO:0010033=IEA, GO:0043499=IEA, GO:0005509=IEA, GO:0072563=IEA, GO:0005622=IDA, GO:0005544=IDA, GO:0007165=TAS, GO:0050819=IEA, GO:0005737=TAS, GO:0005543=TAS, GO:0007596=IEA, GO:0009897=IEA} blood coagulation, negative regulation of apoptotic process, negative regulation of coagulation, response to organic substance, signal transduction cytoplasm, endothelial microparticle, external side of plasma membrane, intracellular calcium ion binding, calcium-dependent phospholipid binding, eukaryotic cell surface binding, phospholipase inhibitor activity, phospholipid binding Human ANXA6 UniProtKB UniProtKB {GO:0005515=PMID:15576473, GO:0005544=PMID:2138016, GO:0042470=GO_REF:0000039, GO:0048471=GO_REF:0000019, GO:0006937=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0006816=GO_REF:0000019} P08133 Annexin A6 protein 20100208 {GO:0005515=IPI, GO:0005544=IDA, GO:0042470=IEA, GO:0048471=IEA, GO:0006937=IEA, GO:0005509=IEA, GO:0006816=IEA} calcium ion transport, regulation of muscle contraction melanosome, perinuclear region of cytoplasm calcium ion binding, calcium-dependent phospholipid binding, protein binding Human ANXA7 BHF-UCL UniProtKB {GO:0005515=PMID:9268363, GO:0009651=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:0008360=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0006874=GO_REF:0000019, GO:0009992=GO_REF:0000019, GO:0005634=PMID:10672515, GO:0005635=GO_REF:0000019, GO:0031982=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0005544=GO_REF:0000037, GO:0007599=GO_REF:0000019, GO:0042584=PMID:9268363, GO:0035176=PMID:21531385, GO:0005789=PMID:10672515, GO:0048306=PMID:12445460} P20073 Annexin A7 protein 20130128 {GO:0005515=IPI, GO:0009651=IEA, GO:0005886=IEA, GO:0008283=IEA, GO:0008360=IEA, GO:0005509=IEA, GO:0006874=IEA, GO:0009992=IEA, GO:0005634=IDA, GO:0005635=IEA, GO:0031982=IEA, GO:0005829=IEA, GO:0005544=IEA, GO:0007599=IEA, GO:0042584=IDA, GO:0035176=IEP, GO:0005789=IDA, GO:0048306=IPI} cell proliferation, cellular calcium ion homeostasis, cellular water homeostasis, hemostasis, regulation of cell shape, response to salt stress, social behavior chromaffin granule membrane, cytosol, endoplasmic reticulum membrane, nuclear envelope, nucleus, plasma membrane, vesicle calcium ion binding, calcium-dependent phospholipid binding, calcium-dependent protein binding, protein binding colocalizes_with Human ANXA8 InterPro UniProtKB {GO:0005544=GO_REF:0000002, GO:0007596=GO_REF:0000037, GO:0005509=GO_REF:0000002} Q5VTM3 Annexin A8 protein 20130413 {GO:0005544=IEA, GO:0007596=IEA, GO:0005509=IEA} blood coagulation calcium ion binding, calcium-dependent phospholipid binding Human InterPro:IPR001464|InterPro:IPR009115|InterPro:IPR018252|InterPro:IPR018502 ANXA8L1 UniProtKB UniProtKB {GO:0005544=GO_REF:0000037, GO:0005509=GO_REF:0000002} Q5T2P8 Annexin A8-like protein 1 protein 20130413 {GO:0005544=IEA, GO:0005509=IEA} calcium ion binding, calcium-dependent phospholipid binding Human UniProtKB-KW:KW-0111 ANXA8L2 UniProtKB UniProtKB {GO:0005544=GO_REF:0000037, GO:0005509=GO_REF:0000002} Q5VT79 Annexin A8-like protein 2 protein 20130413 {GO:0005544=IEA, GO:0005509=IEA} calcium ion binding, calcium-dependent phospholipid binding Human UniProtKB-KW:KW-0111 ANXA9 UniProtKB UniProtKB {GO:0005544=GO_REF:0000002, GO:0016337=PMID:10899159, GO:0005543=PMID:10899159, GO:0009986=PMID:10899159, GO:0015464=PMID:10899159, GO:0005509=GO_REF:0000002, GO:0001786=PMID:12832069, GO:0042803=PMID:10899159, GO:0005829=PMID:12832069} O76027 Annexin A9 protein 20050704 {GO:0005544=IEA, GO:0016337=IDA, GO:0005543=IDA, GO:0009986=IDA, GO:0015464=IDA, GO:0005509=IEA, GO:0001786=IDA, GO:0042803=TAS, GO:0005829=IDA} cell-cell adhesion cell surface, cytosol acetylcholine receptor activity, calcium ion binding, calcium-dependent phospholipid binding, phosphatidylserine binding, phospholipid binding, protein homodimerization activity Human AOC3 UniProtKB UniProtKB {GO:0005261=PMID:19764817, GO:0048038=PMID:9653080, GO:0009986=PMID:9653080, GO:0005886=PMID:9653080, GO:0005507=PMID:19764817, GO:0005509=PMID:19764817, GO:0052596=GO_REF:0000003, GO:0052595=GO_REF:0000003, GO:0052594=GO_REF:0000003, GO:0052593=GO_REF:0000003, GO:0042803=PMID:9653080, GO:0008131=PMID:19764817, GO:0006954=PMID:9653080, GO:0009308=PMID:9653080, GO:0016021=PMID:9653080, GO:0007155=PMID:9653080, GO:0046677=PMID:19764817} Q16853 Membrane primary amine oxidase protein 20111111 {GO:0005261=IDA, GO:0048038=IDA, GO:0009986=IDA, GO:0005886=IDA, GO:0005507=IDA, GO:0005509=IDA, GO:0052596=IEA, GO:0052595=IEA, GO:0052594=IEA, GO:0052593=IEA, GO:0042803=TAS, GO:0008131=IDA, GO:0006954=TAS, GO:0009308=IDA, GO:0016021=IDA, GO:0007155=IDA, GO:0046677=IDA} amine metabolic process, cell adhesion, inflammatory response, response to antibiotic cell surface, integral to membrane, plasma membrane aliphatic-amine oxidase activity, aminoacetone:oxygen oxidoreductase(deaminating) activity, calcium ion binding, cation channel activity, copper ion binding, phenethylamine:oxygen oxidoreductase (deaminating) activity, primary amine oxidase activity, protein homodimerization activity, quinone binding, tryptamine:oxygen oxidoreductase (deaminating) activity Human AOX1 HPA UniProtKB {GO:0008762=GO_REF:0000002, GO:0005506=GO_REF:0000002, GO:0051537=GO_REF:0000037, GO:0004854=PMID:8248161, GO:0050660=GO_REF:0000002, GO:0072593=PMID:7570184, GO:0009055=GO_REF:0000002, GO:0046872=GO_REF:0000002, GO:0004031=GO_REF:0000003, GO:0043546=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0051287=GO_REF:0000002, GO:0006954=PMID:8248161, GO:0016491=GO_REF:0000002} Q06278 Aldehyde oxidase protein 20111111 {GO:0008762=IEA, GO:0005506=IEA, GO:0051537=IEA, GO:0004854=TAS, GO:0050660=IEA, GO:0072593=TAS, GO:0009055=IEA, GO:0046872=IEA, GO:0004031=IEA, GO:0043546=IEA, GO:0005737=IDA, GO:0051287=IEA, GO:0006954=TAS, GO:0016491=IEA} inflammatory response, reactive oxygen species metabolic process cytoplasm 2 iron, 2 sulfur cluster binding, NAD binding, UDP-N-acetylmuramate dehydrogenase activity, aldehyde oxidase activity, electron carrier activity, flavin adenine dinucleotide binding, iron ion binding, metal ion binding, molybdopterin cofactor binding, oxidoreductase activity, xanthine dehydrogenase activity Human AP1AR HPA UniProtKB {GO:0030133=GO_REF:0000054, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0005770=GO_REF:0000039, GO:1900025=PMID:22689987, GO:0034315=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:2000146=GO_REF:0000019, GO:0034613=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0005769=GO_REF:0000039} Q63HQ0 AP-1 complex-associated regulatory protein protein 20110516 {GO:0030133=IDA, GO:0005737=IDA, GO:0005794=IDA, GO:0005770=IEA, GO:1900025=IMP, GO:0034315=IEA, GO:0005730=IDA, GO:2000146=IEA, GO:0034613=IEA, GO:0015031=IEA, GO:0005769=IEA} cellular protein localization, negative regulation of cell motility, negative regulation of substrate adhesion-dependent cell spreading, protein transport, regulation of Arp2/3 complex-mediated actin nucleation Golgi apparatus, cytoplasm, early endosome, late endosome, nucleolus, transport vesicle Human AP1B1 Reactome UniProtKB {GO:0005515=PMID:9733768, GO:0005215=PMID:7987321, GO:0030131=GO_REF:0000002, GO:0006892=Reactome:REACT_11235, GO:0005765=Reactome:REACT_19206, GO:0032588=Reactome:REACT_121003, GO:0006886=GO_REF:0000002, GO:0030117=GO_REF:0000002, GO:0050690=Reactome:REACT_11149, GO:0006897=GO_REF:0000037, GO:0005829=Reactome:REACT_121003, GO:0019886=Reactome:REACT_121399, GO:0030665=GO_REF:0000039, GO:0000139=Reactome:REACT_19391, GO:0008565=GO_REF:0000002, GO:0016032=Reactome:REACT_6185, GO:0016192=GO_REF:0000002, GO:0030659=Reactome:REACT_19255, GO:0016044=Reactome:REACT_11123} Q10567 AP-1 complex subunit beta-1 protein 20130213 {GO:0005515=IPI, GO:0005215=TAS, GO:0030131=IEA, GO:0006892=TAS, GO:0005765=TAS, GO:0032588=TAS, GO:0006886=IEA, GO:0030117=IEA, GO:0050690=TAS, GO:0006897=IEA, GO:0005829=TAS, GO:0019886=TAS, GO:0030665=IEA, GO:0000139=TAS, GO:0008565=IEA, GO:0016032=TAS, GO:0016192=IEA, GO:0030659=TAS, GO:0016044=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, cellular membrane organization, endocytosis, intracellular protein transport, post-Golgi vesicle-mediated transport, regulation of defense response to virus by virus, vesicle-mediated transport, viral reproduction Golgi membrane, clathrin adaptor complex, clathrin-coated vesicle membrane, cytoplasmic vesicle membrane, cytosol, lysosomal membrane, membrane coat, trans-Golgi network membrane protein binding, protein transporter activity, transporter activity Human AP1G1 BHF-UCL UniProtKB {GO:0005515=PMID:12505986, GO:0005802=GO_REF:0000019, GO:0005215=PMID:9733768, GO:0048471=GO_REF:0000019, GO:0030131=GO_REF:0000002, GO:0030136=PMID:12536145, GO:0030119=PMID:9653655, GO:0005765=Reactome:REACT_19206, GO:0006886=GO_REF:0000002, GO:0030117=GO_REF:0000002, GO:0005829=Reactome:REACT_121003, GO:0019886=Reactome:REACT_121399, GO:0005737=PMID:9733768, GO:0016032=Reactome:REACT_6185, GO:0016192=GO_REF:0000002, GO:0030659=Reactome:REACT_19255, GO:0005794=PMID:9733768, GO:0006892=Reactome:REACT_11235, GO:0032588=Reactome:REACT_121003, GO:0050690=Reactome:REACT_11149, GO:0006897=GO_REF:0000037, GO:0030665=GO_REF:0000024, GO:0000139=Reactome:REACT_19391, GO:0008565=GO_REF:0000002, GO:0019894=PMID:19841138, GO:0055037=PMID:19841138, GO:0016044=Reactome:REACT_11123} O43747 AP-1 complex subunit gamma-1 protein 20110308 {GO:0005515=IPI, GO:0005802=IEA, GO:0005215=TAS, GO:0048471=IEA, GO:0030131=IEA, GO:0030136=IDA, GO:0030119=TAS, GO:0005765=TAS, GO:0006886=IEA, GO:0030117=IEA, GO:0005829=TAS, GO:0019886=TAS, GO:0005737=TAS, GO:0016032=TAS, GO:0016192=IEA, GO:0030659=TAS, GO:0005794=IDA, GO:0006892=TAS, GO:0032588=TAS, GO:0050690=TAS, GO:0006897=IEA, GO:0030665=ISS, GO:0000139=TAS, GO:0008565=IEA, GO:0019894=IPI, GO:0055037=IDA, GO:0016044=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, cellular membrane organization, endocytosis, intracellular protein transport, post-Golgi vesicle-mediated transport, regulation of defense response to virus by virus, vesicle-mediated transport, viral reproduction AP-type membrane coat adaptor complex, Golgi apparatus, Golgi membrane, clathrin adaptor complex, clathrin-coated vesicle, clathrin-coated vesicle membrane, cytoplasm, cytoplasmic vesicle membrane, cytosol, lysosomal membrane, membrane coat, perinuclear region of cytoplasm, recycling endosome, trans-Golgi network, trans-Golgi network membrane kinesin binding, protein binding, protein transporter activity, transporter activity Human UniProtKB:Q8R525 AP1G2 UniProtKB UniProtKB {GO:0030133=GO_REF:0000024, GO:0005515=PMID:12505986, GO:0030131=GO_REF:0000002, GO:0005794=PMID:9762922, GO:0030121=PMID:9733768, GO:0005798=GO_REF:0000024, GO:0006886=GO_REF:0000002, GO:0030117=GO_REF:0000002, GO:0016020=GO_REF:0000024, GO:0019048=GO_REF:0000037, GO:0008565=GO_REF:0000002, GO:0016192=GO_REF:0000002, GO:0010008=GO_REF:0000039} Q86V28 AP1G2 protein protein 20041006 {GO:0030133=ISS, GO:0005515=IPI, GO:0030131=IEA, GO:0005794=TAS, GO:0030121=TAS, GO:0005798=ISS, GO:0006886=IEA, GO:0030117=IEA, GO:0016020=ISS, GO:0019048=IEA, GO:0008565=IEA, GO:0016192=IEA, GO:0010008=IEA} intracellular protein transport, vesicle-mediated transport, virus-host interaction AP-1 adaptor complex, Golgi apparatus, Golgi-associated vesicle, clathrin adaptor complex, endosome membrane, membrane, membrane coat, transport vesicle protein binding, protein transporter activity Human UniProtKB:O75843 AP1M1 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0030131=GO_REF:0000002, GO:0032438=PMID:19841138, GO:0006892=Reactome:REACT_11235, GO:0005765=Reactome:REACT_19206, GO:0032588=Reactome:REACT_121003, GO:0006886=GO_REF:0000002, GO:0050690=Reactome:REACT_11149, GO:0005829=Reactome:REACT_121003, GO:0019886=Reactome:REACT_121399, GO:0030665=GO_REF:0000039, GO:0000139=Reactome:REACT_19391, GO:0019048=GO_REF:0000037, GO:0006810=GO_REF:0000002, GO:0035646=PMID:19841138, GO:0016032=Reactome:REACT_6185, GO:0016192=GO_REF:0000002, GO:0030659=Reactome:REACT_19255, GO:0016044=Reactome:REACT_11123} Q9BXS5 AP-1 complex subunit mu-1 protein 20130415 {GO:0005515=IPI, GO:0030131=IEA, GO:0032438=IMP, GO:0006892=TAS, GO:0005765=TAS, GO:0032588=TAS, GO:0006886=IEA, GO:0050690=TAS, GO:0005829=TAS, GO:0019886=TAS, GO:0030665=IEA, GO:0000139=TAS, GO:0019048=IEA, GO:0006810=IEA, GO:0035646=IMP, GO:0016032=TAS, GO:0016192=IEA, GO:0030659=TAS, GO:0016044=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, cellular membrane organization, endosome to melanosome transport, intracellular protein transport, melanosome organization, post-Golgi vesicle-mediated transport, regulation of defense response to virus by virus, transport, vesicle-mediated transport, viral reproduction, virus-host interaction Golgi membrane, clathrin adaptor complex, clathrin-coated vesicle membrane, cytoplasmic vesicle membrane, cytosol, lysosomal membrane, trans-Golgi network membrane protein binding Human UniProtKB:Q14872 AP1M2 Reactome UniProtKB {GO:0030131=GO_REF:0000002, GO:0006892=Reactome:REACT_11235, GO:0006605=PMID:10338135, GO:0005765=Reactome:REACT_19206, GO:0032588=Reactome:REACT_121003, GO:0006886=GO_REF:0000002, GO:0006903=PMID:10338135, GO:0050690=Reactome:REACT_11149, GO:0005829=Reactome:REACT_121003, GO:0030665=GO_REF:0000039, GO:0019886=Reactome:REACT_121399, GO:0000139=Reactome:REACT_19391, GO:0016032=Reactome:REACT_6185, GO:0016192=GO_REF:0000002, GO:0030659=Reactome:REACT_19255, GO:0016044=Reactome:REACT_11123} Q9Y6Q5 AP-1 complex subunit mu-2 protein 20070808 {GO:0030131=IEA, GO:0006892=TAS, GO:0006605=TAS, GO:0005765=TAS, GO:0032588=TAS, GO:0006886=IEA, GO:0006903=TAS, GO:0050690=TAS, GO:0005829=TAS, GO:0030665=IEA, GO:0019886=TAS, GO:0000139=TAS, GO:0016032=TAS, GO:0016192=IEA, GO:0030659=TAS, GO:0016044=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, cellular membrane organization, intracellular protein transport, post-Golgi vesicle-mediated transport, protein targeting, regulation of defense response to virus by virus, vesicle targeting, vesicle-mediated transport, viral reproduction Golgi membrane, clathrin adaptor complex, clathrin-coated vesicle membrane, cytoplasmic vesicle membrane, cytosol, lysosomal membrane, trans-Golgi network membrane Human AP1S1 Reactome UniProtKB {GO:0030121=PMID:9733768, GO:0006892=Reactome:REACT_11235, GO:0009615=PMID:16548883, GO:0005765=Reactome:REACT_19206, GO:0032588=Reactome:REACT_121003, GO:0006886=GO_REF:0000002, GO:0030117=GO_REF:0000002, GO:0006898=PMID:9733768, GO:0050690=Reactome:REACT_11149, GO:0005829=Reactome:REACT_121003, GO:0019886=Reactome:REACT_121399, GO:0005905=GO_REF:0000039, GO:0000139=Reactome:REACT_19391, GO:0008565=GO_REF:0000002, GO:0016032=Reactome:REACT_6185, GO:0030130=GO_REF:0000029, GO:0016192=GO_REF:0000002, GO:0030659=Reactome:REACT_19255, GO:0016044=Reactome:REACT_11123} P61966 AP-1 complex subunit sigma-1A protein 20070808 {GO:0030121=TAS, GO:0006892=TAS, GO:0009615=IEP, GO:0005765=TAS, GO:0032588=TAS, GO:0006886=IEA, GO:0030117=IEA, GO:0006898=TAS, GO:0050690=TAS, GO:0005829=TAS, GO:0019886=TAS, GO:0005905=IEA, GO:0000139=TAS, GO:0008565=IEA, GO:0016032=TAS, GO:0030130=NAS, GO:0016192=IEA, GO:0030659=TAS, GO:0016044=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, cellular membrane organization, intracellular protein transport, post-Golgi vesicle-mediated transport, receptor-mediated endocytosis, regulation of defense response to virus by virus, response to virus, vesicle-mediated transport, viral reproduction AP-1 adaptor complex, Golgi membrane, clathrin coat of trans-Golgi network vesicle, coated pit, cytoplasmic vesicle membrane, cytosol, lysosomal membrane, membrane coat, trans-Golgi network membrane protein transporter activity Human AP1S2 Reactome UniProtKB {GO:0006892=Reactome:REACT_11235, GO:0030119=PMID:9733768, GO:0005765=Reactome:REACT_19206, GO:0032588=Reactome:REACT_121003, GO:0006886=GO_REF:0000002, GO:0030117=GO_REF:0000002, GO:0050690=Reactome:REACT_11149, GO:0006897=GO_REF:0000037, GO:0005829=Reactome:REACT_121003, GO:0019886=Reactome:REACT_121399, GO:0005905=GO_REF:0000039, GO:0000139=Reactome:REACT_19391, GO:0008565=GO_REF:0000002, GO:0016032=Reactome:REACT_6185, GO:0016192=GO_REF:0000002, GO:0030659=Reactome:REACT_19255, GO:0016044=Reactome:REACT_11123} P56377 AP-1 complex subunit sigma-2 protein 20070808 {GO:0006892=TAS, GO:0030119=TAS, GO:0005765=TAS, GO:0032588=TAS, GO:0006886=IEA, GO:0030117=IEA, GO:0050690=TAS, GO:0006897=IEA, GO:0005829=TAS, GO:0019886=TAS, GO:0005905=IEA, GO:0000139=TAS, GO:0008565=IEA, GO:0016032=TAS, GO:0016192=IEA, GO:0030659=TAS, GO:0016044=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, cellular membrane organization, endocytosis, intracellular protein transport, post-Golgi vesicle-mediated transport, regulation of defense response to virus by virus, vesicle-mediated transport, viral reproduction AP-type membrane coat adaptor complex, Golgi membrane, coated pit, cytoplasmic vesicle membrane, cytosol, lysosomal membrane, membrane coat, trans-Golgi network membrane protein transporter activity Human AP1S3 Reactome UniProtKB {GO:0006892=Reactome:REACT_11235, GO:0005765=Reactome:REACT_19206, GO:0006886=GO_REF:0000002, GO:0032588=Reactome:REACT_120943, GO:0030117=GO_REF:0000002, GO:0006897=GO_REF:0000037, GO:0050690=Reactome:REACT_11149, GO:0005829=Reactome:REACT_121003, GO:0019886=Reactome:REACT_121399, GO:0005905=GO_REF:0000039, GO:0000139=Reactome:REACT_19391, GO:0008565=GO_REF:0000002, GO:0016032=Reactome:REACT_6185, GO:0016192=GO_REF:0000002, GO:0030659=Reactome:REACT_19255, GO:0016044=Reactome:REACT_11123} Q96PC3 AP-1 complex subunit sigma-3 protein 20130213 {GO:0006892=TAS, GO:0005765=TAS, GO:0006886=IEA, GO:0032588=TAS, GO:0030117=IEA, GO:0006897=IEA, GO:0050690=TAS, GO:0005829=TAS, GO:0019886=TAS, GO:0005905=IEA, GO:0000139=TAS, GO:0008565=IEA, GO:0016032=TAS, GO:0016192=IEA, GO:0030659=TAS, GO:0016044=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, cellular membrane organization, endocytosis, intracellular protein transport, post-Golgi vesicle-mediated transport, regulation of defense response to virus by virus, vesicle-mediated transport, viral reproduction Golgi membrane, coated pit, cytoplasmic vesicle membrane, cytosol, lysosomal membrane, membrane coat, trans-Golgi network membrane protein transporter activity Human AP2A1 Reactome UniProtKB {GO:0005515=PMID:19116314, GO:0048011=Reactome:REACT_11061, GO:0005886=Reactome:REACT_121177, GO:0030122=PMID:12036598, GO:0042059=Reactome:REACT_12484, GO:0007268=Reactome:REACT_13685, GO:0008022=GO_REF:0000019, GO:0006895=PMID:12036598, GO:0006886=PMID:12036598, GO:0050690=Reactome:REACT_11200, GO:0006897=PMID:12036598, GO:0005829=Reactome:REACT_11177, GO:0030666=Reactome:REACT_18330, GO:0019886=Reactome:REACT_121399, GO:0016323=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0007411=Reactome:REACT_18266, GO:0008565=GO_REF:0000002, GO:0016032=Reactome:REACT_6185, GO:0030130=PMID:12036598} O95782 AP-2 complex subunit alpha-1 protein 20070808 {GO:0005515=IPI, GO:0048011=TAS, GO:0005886=TAS, GO:0030122=NAS, GO:0042059=TAS, GO:0007268=TAS, GO:0008022=IEA, GO:0006895=NAS, GO:0006886=NAS, GO:0050690=TAS, GO:0006897=NAS, GO:0005829=TAS, GO:0030666=TAS, GO:0019886=TAS, GO:0016323=IEA, GO:0016324=IEA, GO:0007173=TAS, GO:0007411=TAS, GO:0008565=IEA, GO:0016032=TAS, GO:0030130=NAS} Golgi to endosome transport, antigen processing and presentation of exogenous peptide antigen via MHC class II, axon guidance, endocytosis, epidermal growth factor receptor signaling pathway, intracellular protein transport, negative regulation of epidermal growth factor receptor signaling pathway, neurotrophin TRK receptor signaling pathway, regulation of defense response to virus by virus, synaptic transmission, viral reproduction AP-2 adaptor complex, apical plasma membrane, basolateral plasma membrane, clathrin coat of trans-Golgi network vesicle, cytosol, endocytic vesicle membrane, plasma membrane protein C-terminus binding, protein binding, protein transporter activity Human AP2A2 IntAct UniProtKB {GO:0005515=PMID:22323290, GO:0048011=Reactome:REACT_11061, GO:0030131=GO_REF:0000002, GO:0005886=Reactome:REACT_121177, GO:0030122=GO_REF:0000029, GO:0042059=Reactome:REACT_12484, GO:0007268=Reactome:REACT_13685, GO:0006886=GO_REF:0000029, GO:0030117=GO_REF:0000002, GO:0050690=Reactome:REACT_11200, GO:0006897=GO_REF:0000037, GO:0008289=GO_REF:0000037, GO:0005829=Reactome:REACT_11177, GO:0030666=Reactome:REACT_18330, GO:0019886=Reactome:REACT_121399, GO:0003674=GO_REF:0000015, GO:0007173=Reactome:REACT_9417, GO:0007411=Reactome:REACT_18266, GO:0008565=GO_REF:0000002, GO:0016032=Reactome:REACT_6185, GO:0016192=GO_REF:0000002} O94973 AP-2 complex subunit alpha-2 protein 20130415 {GO:0005515=IPI, GO:0048011=TAS, GO:0030131=IEA, GO:0005886=TAS, GO:0030122=NAS, GO:0042059=TAS, GO:0007268=TAS, GO:0006886=NAS, GO:0030117=IEA, GO:0050690=TAS, GO:0006897=IEA, GO:0008289=IEA, GO:0005829=TAS, GO:0030666=TAS, GO:0019886=TAS, GO:0003674=ND, GO:0007173=TAS, GO:0007411=TAS, GO:0008565=IEA, GO:0016032=TAS, GO:0016192=IEA} antigen processing and presentation of exogenous peptide antigen via MHC class II, axon guidance, endocytosis, epidermal growth factor receptor signaling pathway, intracellular protein transport, negative regulation of epidermal growth factor receptor signaling pathway, neurotrophin TRK receptor signaling pathway, regulation of defense response to virus by virus, synaptic transmission, vesicle-mediated transport, viral reproduction AP-2 adaptor complex, clathrin adaptor complex, cytosol, endocytic vesicle membrane, membrane coat, plasma membrane lipid binding, molecular_function, protein binding, protein transporter activity Human UniProtKB:P98078 AP2B1 InterPro UniProtKB {GO:0005515=PMID:12221107, GO:0005802=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0030131=GO_REF:0000002, GO:0005886=Reactome:REACT_120835, GO:0042059=Reactome:REACT_12484, GO:0007268=Reactome:REACT_13685, GO:0006886=GO_REF:0000002, GO:0032403=GO_REF:0000019, GO:0030117=GO_REF:0000002, GO:0050690=Reactome:REACT_11200, GO:0005829=Reactome:REACT_11177, GO:0030666=Reactome:REACT_18330, GO:0019886=Reactome:REACT_121399, GO:0005905=GO_REF:0000039, GO:0007173=Reactome:REACT_9417, GO:0007411=Reactome:REACT_18266, GO:0030276=PMID:19509056, GO:0008565=GO_REF:0000002, GO:0016032=Reactome:REACT_6185, GO:0016192=GO_REF:0000002, GO:0030669=Reactome:REACT_121177, GO:0048268=GO_REF:0000019} Q7Z451 AP-2 complex subunit beta protein 20130413 {GO:0005515=IPI, GO:0005802=IEA, GO:0048011=TAS, GO:0030131=IEA, GO:0005886=TAS, GO:0042059=TAS, GO:0007268=TAS, GO:0006886=IEA, GO:0032403=IEA, GO:0030117=IEA, GO:0050690=TAS, GO:0005829=TAS, GO:0030666=TAS, GO:0019886=TAS, GO:0005905=IEA, GO:0007173=TAS, GO:0007411=TAS, GO:0030276=IPI, GO:0008565=IEA, GO:0016032=TAS, GO:0016192=IEA, GO:0030669=TAS, GO:0048268=IEA} antigen processing and presentation of exogenous peptide antigen via MHC class II, axon guidance, clathrin coat assembly, epidermal growth factor receptor signaling pathway, intracellular protein transport, negative regulation of epidermal growth factor receptor signaling pathway, neurotrophin TRK receptor signaling pathway, regulation of defense response to virus by virus, synaptic transmission, vesicle-mediated transport, viral reproduction clathrin adaptor complex, clathrin-coated endocytic vesicle membrane, coated pit, cytosol, endocytic vesicle membrane, membrane coat, plasma membrane, trans-Golgi network clathrin binding, protein binding, protein complex binding, protein transporter activity Human InterPro:IPR008152|InterPro:IPR013037|InterPro:IPR015151 AP2M1 Reactome UniProtKB {GO:0005515=PMID:19419997, GO:0005215=PMID:8595912, GO:0048011=Reactome:REACT_11061, GO:0030131=GO_REF:0000002, GO:0030132=GO_REF:0000002, GO:0005886=Reactome:REACT_120835, GO:0042059=Reactome:REACT_12484, GO:0007268=Reactome:REACT_13685, GO:0005765=Reactome:REACT_10083, GO:0006886=GO_REF:0000002, GO:0050690=Reactome:REACT_11200, GO:0008289=GO_REF:0000037, GO:0005829=Reactome:REACT_11177, GO:0030666=Reactome:REACT_18330, GO:0005739=GO_REF:0000019, GO:0019886=Reactome:REACT_121399, GO:0007173=Reactome:REACT_9417, GO:0007411=Reactome:REACT_18266, GO:0016032=Reactome:REACT_6185, GO:0016192=GO_REF:0000002, GO:0030669=Reactome:REACT_121177, GO:0016044=Reactome:REACT_11123} Q96CW1 AP-2 complex subunit mu protein 20130213 {GO:0005515=IPI, GO:0005215=TAS, GO:0048011=TAS, GO:0030131=IEA, GO:0030132=IEA, GO:0005886=TAS, GO:0042059=TAS, GO:0007268=TAS, GO:0005765=TAS, GO:0006886=IEA, GO:0050690=TAS, GO:0008289=IEA, GO:0005829=TAS, GO:0030666=TAS, GO:0005739=IEA, GO:0019886=TAS, GO:0007173=TAS, GO:0007411=TAS, GO:0016032=TAS, GO:0016192=IEA, GO:0030669=TAS, GO:0016044=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, axon guidance, cellular membrane organization, epidermal growth factor receptor signaling pathway, intracellular protein transport, negative regulation of epidermal growth factor receptor signaling pathway, neurotrophin TRK receptor signaling pathway, regulation of defense response to virus by virus, synaptic transmission, vesicle-mediated transport, viral reproduction clathrin adaptor complex, clathrin coat of coated pit, clathrin-coated endocytic vesicle membrane, cytosol, endocytic vesicle membrane, lysosomal membrane, mitochondrion, plasma membrane lipid binding, protein binding, transporter activity Human AP2S1 Reactome UniProtKB {GO:0005215=PMID:9040778, GO:0048011=Reactome:REACT_11061, GO:0005886=Reactome:REACT_120835, GO:0030122=PMID:10753805, GO:0042059=Reactome:REACT_12484, GO:0007268=Reactome:REACT_13685, GO:0006886=GO_REF:0000002, GO:0050690=Reactome:REACT_11200, GO:0005829=Reactome:REACT_11177, GO:0030666=Reactome:REACT_18330, GO:0019886=Reactome:REACT_121399, GO:0007173=Reactome:REACT_9417, GO:0030100=PMID:10753805, GO:0007411=Reactome:REACT_18266, GO:0008565=PMID:10753805, GO:0016032=Reactome:REACT_6185, GO:0016192=GO_REF:0000002, GO:0030669=Reactome:REACT_121177, GO:0048268=PMID:10753805} P53680 AP-2 complex subunit sigma protein 20130213 {GO:0005215=NAS, GO:0048011=TAS, GO:0005886=TAS, GO:0030122=TAS, GO:0042059=TAS, GO:0007268=TAS, GO:0006886=IEA, GO:0050690=TAS, GO:0005829=TAS, GO:0030666=TAS, GO:0019886=TAS, GO:0007173=TAS, GO:0030100=TAS, GO:0007411=TAS, GO:0008565=NAS, GO:0016032=TAS, GO:0016192=IEA, GO:0030669=TAS, GO:0048268=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, axon guidance, clathrin coat assembly, epidermal growth factor receptor signaling pathway, intracellular protein transport, negative regulation of epidermal growth factor receptor signaling pathway, neurotrophin TRK receptor signaling pathway, regulation of defense response to virus by virus, regulation of endocytosis, synaptic transmission, vesicle-mediated transport, viral reproduction AP-2 adaptor complex, clathrin-coated endocytic vesicle membrane, cytosol, endocytic vesicle membrane, plasma membrane protein transporter activity, transporter activity Human AP3B1 PINC UniProtKB {GO:0048490=GO_REF:0000024, GO:0005794=GO_REF:0000039, GO:0019903=PMID:17622474, GO:0032438=PMID:19841138, GO:0030123=GO_REF:0000002, GO:0006886=PMID:9931340, GO:0006897=GO_REF:0000037, GO:0030665=GO_REF:0000039, GO:0007596=GO_REF:0000019, GO:0051138=GO_REF:0000019, GO:0006622=GO_REF:0000019, GO:0048007=GO_REF:0000019, GO:0008089=GO_REF:0000024, GO:0016192=GO_REF:0000002} O00203 AP-3 complex subunit beta-1 protein 20030904 {GO:0048490=ISS, GO:0005794=IEA, GO:0019903=IPI, GO:0032438=IMP, GO:0030123=IEA, GO:0006886=TAS, GO:0006897=IEA, GO:0030665=IEA, GO:0007596=IEA, GO:0051138=IEA, GO:0006622=IEA, GO:0048007=IEA, GO:0008089=ISS, GO:0016192=IEA} anterograde axon cargo transport, anterograde synaptic vesicle transport, antigen processing and presentation, exogenous lipid antigen via MHC class Ib, blood coagulation, endocytosis, intracellular protein transport, melanosome organization, positive regulation of NK T cell differentiation, protein targeting to lysosome, vesicle-mediated transport AP-3 adaptor complex, Golgi apparatus, clathrin-coated vesicle membrane protein phosphatase binding Human AP3B2 HPA UniProtKB {GO:0005215=PMID:7671305, GO:0048490=GO_REF:0000024, GO:0005794=GO_REF:0000052, GO:0030137=PMID:7671305, GO:0030123=GO_REF:0000002, GO:0006892=PMID:7671305, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006886=GO_REF:0000002, GO:0030117=GO_REF:0000002, GO:0006897=GO_REF:0000037, GO:0030665=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0008089=GO_REF:0000024, GO:0016192=GO_REF:0000002} Q13367 AP-3 complex subunit beta-2 protein 20111111 {GO:0005215=TAS, GO:0048490=ISS, GO:0005794=IDA, GO:0030137=TAS, GO:0030123=IEA, GO:0006892=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0006886=IEA, GO:0030117=IEA, GO:0006897=IEA, GO:0030665=IEA, GO:0005737=IDA, GO:0008089=ISS, GO:0016192=IEA} anterograde axon cargo transport, anterograde synaptic vesicle transport, endocytosis, intracellular protein transport, post-Golgi vesicle-mediated transport, vesicle-mediated transport AP-3 adaptor complex, COPI-coated vesicle, Golgi apparatus, clathrin-coated vesicle membrane, cytoplasm, membrane coat, nucleolus, nucleus transporter activity Human AP3D1 BHF-UCL UniProtKB {GO:0005215=PMID:9303295, GO:0048490=GO_REF:0000024, GO:0006726=PMID:9303295, GO:0005794=PMID:9151686, GO:0033365=GO_REF:0000019, GO:0061088=PMID:17349999, GO:0048499=GO_REF:0000019, GO:0006886=GO_REF:0000019, GO:0030117=GO_REF:0000002, GO:0000139=GO_REF:0000039, GO:0051138=GO_REF:0000019, GO:0043195=GO_REF:0000019, GO:0008565=GO_REF:0000002, GO:0048007=GO_REF:0000019, GO:0008089=GO_REF:0000024, GO:0016192=GO_REF:0000002, GO:0010008=PMID:16162817} O14617 AP-3 complex subunit delta-1 protein 20100505 {GO:0005215=TAS, GO:0048490=ISS, GO:0006726=TAS, GO:0005794=TAS, GO:0033365=IEA, GO:0061088=IMP, GO:0048499=IEA, GO:0006886=IEA, GO:0030117=IEA, GO:0000139=IEA, GO:0051138=IEA, GO:0043195=IEA, GO:0008565=IEA, GO:0048007=IEA, GO:0008089=ISS, GO:0016192=IEA, GO:0010008=IDA} anterograde axon cargo transport, anterograde synaptic vesicle transport, antigen processing and presentation, exogenous lipid antigen via MHC class Ib, eye pigment biosynthetic process, intracellular protein transport, positive regulation of NK T cell differentiation, protein localization to organelle, regulation of sequestering of zinc ion, synaptic vesicle membrane organization, vesicle-mediated transport Golgi apparatus, Golgi membrane, endosome membrane, membrane coat, terminal bouton protein transporter activity, transporter activity Human AP3M1 PINC UniProtKB {GO:0005515=PMID:19116314, GO:0048490=GO_REF:0000024, GO:0030131=GO_REF:0000002, GO:0005794=GO_REF:0000039, GO:0006622=PMID:10024875, GO:0008089=GO_REF:0000024, GO:0005764=PMID:10024875} Q9Y2T2 AP-3 complex subunit mu-1 protein 20030904 {GO:0005515=IPI, GO:0048490=ISS, GO:0030131=IEA, GO:0005794=IEA, GO:0006622=TAS, GO:0008089=ISS, GO:0005764=TAS} anterograde axon cargo transport, anterograde synaptic vesicle transport, protein targeting to lysosome Golgi apparatus, clathrin adaptor complex, lysosome protein binding Human AP3M2 InterPro UniProtKB {GO:0048490=GO_REF:0000024, GO:0030131=GO_REF:0000002, GO:0005794=GO_REF:0000039, GO:0006810=GO_REF:0000002, GO:0008089=GO_REF:0000024, GO:0030119=PMID:8076832, GO:0016192=GO_REF:0000002, GO:0006886=GO_REF:0000002} Q7Z472 AP3M2 protein protein 20130413 {GO:0048490=ISS, GO:0030131=IEA, GO:0005794=IEA, GO:0006810=IEA, GO:0008089=ISS, GO:0030119=TAS, GO:0016192=IEA, GO:0006886=IEA} anterograde axon cargo transport, anterograde synaptic vesicle transport, intracellular protein transport, transport, vesicle-mediated transport AP-type membrane coat adaptor complex, Golgi apparatus, clathrin adaptor complex Human InterPro:IPR001392|InterPro:IPR008968|InterPro:IPR018240 AP3S1 PINC UniProtKB {GO:0005515=PMID:16162817, GO:0030133=PMID:9118953, GO:0008286=PMID:9792713, GO:0005215=PMID:9118953, GO:0048490=GO_REF:0000024, GO:0005794=GO_REF:0000039, GO:0030123=PMID:9118953, GO:0030119=PMID:8697810, GO:0006886=GO_REF:0000002, GO:0008565=GO_REF:0000002, GO:0008089=GO_REF:0000024, GO:0016192=GO_REF:0000002, GO:0030659=GO_REF:0000039} Q92572 AP-3 complex subunit sigma-1 protein 20030904 {GO:0005515=IPI, GO:0030133=TAS, GO:0008286=TAS, GO:0005215=NAS, GO:0048490=ISS, GO:0005794=IEA, GO:0030123=IDA, GO:0030119=TAS, GO:0006886=IEA, GO:0008565=IEA, GO:0008089=ISS, GO:0016192=IEA, GO:0030659=IEA} anterograde axon cargo transport, anterograde synaptic vesicle transport, insulin receptor signaling pathway, intracellular protein transport, vesicle-mediated transport AP-3 adaptor complex, AP-type membrane coat adaptor complex, Golgi apparatus, cytoplasmic vesicle membrane, transport vesicle protein binding, protein transporter activity, transporter activity Human AP3S2 UniProtKB UniProtKB {GO:0048490=GO_REF:0000024, GO:0005794=GO_REF:0000039, GO:0030123=PMID:9118953, GO:0008565=GO_REF:0000002, GO:0006810=GO_REF:0000002, GO:0008089=GO_REF:0000024, GO:0016192=GO_REF:0000002, GO:0006886=GO_REF:0000002, GO:0030659=GO_REF:0000039} P59780 AP-3 complex subunit sigma-2 protein 20120810 {GO:0048490=ISS, GO:0005794=IEA, GO:0030123=IDA, GO:0008565=IEA, GO:0006810=IEA, GO:0008089=ISS, GO:0016192=IEA, GO:0006886=IEA, GO:0030659=IEA} anterograde axon cargo transport, anterograde synaptic vesicle transport, intracellular protein transport, transport, vesicle-mediated transport AP-3 adaptor complex, Golgi apparatus, cytoplasmic vesicle membrane protein transporter activity Human UniProtKB:Q8BSZ2 AP4B1 PINC UniProtKB {GO:0005802=GO_REF:0000019, GO:0005215=PMID:10066790, GO:0030131=GO_REF:0000002, GO:0005794=GO_REF:0000039, GO:0008565=GO_REF:0000002, GO:0016192=GO_REF:0000002, GO:0006886=GO_REF:0000002, GO:0030117=GO_REF:0000002} Q9Y6B7 AP-4 complex subunit beta-1 protein 20030904 {GO:0005802=IEA, GO:0005215=TAS, GO:0030131=IEA, GO:0005794=IEA, GO:0008565=IEA, GO:0016192=IEA, GO:0006886=IEA, GO:0030117=IEA} intracellular protein transport, vesicle-mediated transport Golgi apparatus, clathrin adaptor complex, membrane coat, trans-Golgi network protein transporter activity, transporter activity Human AP4E1 InterPro UniProtKB {GO:0030126=GO_REF:0000002, GO:0005198=GO_REF:0000002, GO:0016192=GO_REF:0000002, GO:0006886=GO_REF:0000002, GO:0030117=GO_REF:0000002} Q9UPM8 AP-4 complex subunit epsilon-1 protein 20130413 {GO:0030126=IEA, GO:0005198=IEA, GO:0016192=IEA, GO:0006886=IEA, GO:0030117=IEA} intracellular protein transport, vesicle-mediated transport COPI vesicle coat, membrane coat structural molecule activity Human InterPro:IPR011710 AP4M1 PINC UniProtKB {GO:0005802=PMID:20230749, GO:0005215=PMID:10066790, GO:0005905=GO_REF:0000039, GO:0030131=GO_REF:0000002, GO:0000138=PMID:10066790, GO:0006810=GO_REF:0000002, GO:0030119=PMID:10066790, GO:0016192=PMID:10066790, GO:0006895=PMID:20230749, GO:0006886=PMID:20230749} O00189 AP-4 complex subunit mu-1 protein 20030904 {GO:0005802=IDA, GO:0005215=TAS, GO:0005905=IEA, GO:0030131=IEA, GO:0000138=TAS, GO:0006810=IEA, GO:0030119=TAS, GO:0016192=TAS, GO:0006895=IMP, GO:0006886=IMP} Golgi to endosome transport, intracellular protein transport, transport, vesicle-mediated transport AP-type membrane coat adaptor complex, Golgi trans cisterna, clathrin adaptor complex, coated pit, trans-Golgi network transporter activity Human AP4S1 PINC UniProtKB {GO:0005215=PMID:10436028, GO:0005905=GO_REF:0000039, GO:0005794=GO_REF:0000039, GO:0008565=GO_REF:0000002} Q9Y587 AP-4 complex subunit sigma-1 protein 20030904 {GO:0005215=TAS, GO:0005905=IEA, GO:0005794=IEA, GO:0008565=IEA} Golgi apparatus, coated pit protein transporter activity, transporter activity Human APAF1 HPA UniProtKB {GO:0005515=PMID:17274640, GO:0008635=Reactome:REACT_607, GO:0005794=GO_REF:0000052, GO:0006919=PMID:21827945, GO:0005730=GO_REF:0000052, GO:0006915=Reactome:REACT_578, GO:0001843=GO_REF:0000019, GO:0006952=GO_REF:0000002, GO:0042981=PMID:10441496, GO:0005634=GO_REF:0000052, GO:0051402=GO_REF:0000019, GO:0008656=PMID:15009102, GO:0005524=GO_REF:0000037, GO:0097193=Reactome:REACT_964, GO:0005829=Reactome:REACT_2165, GO:0007399=PMID:9753320, GO:0042802=GO_REF:0000019, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0043293=PMID:21827945, GO:0000166=PMID:10383829, GO:0043531=GO_REF:0000002, GO:0006309=GO_REF:0000019, GO:0030900=GO_REF:0000019} O14727 Apoptotic protease-activating factor 1 protein 20101115 {GO:0005515=IPI, GO:0008635=TAS, GO:0005794=IDA, GO:0006919=IDA, GO:0005730=IDA, GO:0006915=TAS, GO:0001843=IEA, GO:0006952=IEA, GO:0042981=TAS, GO:0005634=IDA, GO:0051402=IEA, GO:0008656=NAS, GO:0005524=IEA, GO:0097193=TAS, GO:0005829=TAS, GO:0007399=TAS, GO:0042802=IEA, GO:0005622=IEA, GO:0005737=IDA, GO:0043293=IDA, GO:0000166=TAS, GO:0043531=IEA, GO:0006309=IEA, GO:0030900=IEA} activation of cysteine-type endopeptidase activity involved in apoptotic process, activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c, apoptotic DNA fragmentation, apoptotic process, defense response, forebrain development, intrinsic apoptotic signaling pathway, nervous system development, neural tube closure, neuron apoptotic process, regulation of apoptotic process Golgi apparatus, apoptosome, cytoplasm, cytosol, intracellular, nucleolus, nucleus ADP binding, ATP binding, cysteine-type endopeptidase activator activity involved in apoptotic process, identical protein binding, nucleotide binding, protein binding Human APBA1 IntAct UniProtKB {GO:0005515=PMID:8887653, GO:0010468=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0014051=GO_REF:0000019, GO:0005546=GO_REF:0000019, GO:0007268=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0030165=GO_REF:0000019, GO:0006886=GO_REF:0000019, GO:0014047=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0008021=PMID:9753324, GO:0007399=PMID:9753324, GO:0043234=GO_REF:0000019, GO:0006461=PMID:9753324, GO:0001540=GO_REF:0000019, GO:0035264=GO_REF:0000019, GO:0008088=PMID:9822620, GO:0007626=GO_REF:0000019, GO:0007155=PMID:9753324} Q02410 Amyloid beta A4 precursor protein-binding family A member 1 protein 20130415 {GO:0005515=IPI, GO:0010468=IEA, GO:0005886=IEA, GO:0014051=IEA, GO:0005546=IEA, GO:0007268=IEA, GO:0005634=IEA, GO:0030165=IEA, GO:0006886=IEA, GO:0014047=IEA, GO:0032403=IEA, GO:0001701=IEA, GO:0008021=TAS, GO:0007399=TAS, GO:0043234=IEA, GO:0006461=TAS, GO:0001540=IEA, GO:0035264=IEA, GO:0008088=TAS, GO:0007626=IEA, GO:0007155=TAS} axon cargo transport, cell adhesion, gamma-aminobutyric acid secretion, glutamate secretion, in utero embryonic development, intracellular protein transport, locomotory behavior, multicellular organism growth, nervous system development, protein complex assembly, regulation of gene expression, synaptic transmission nucleus, plasma membrane, protein complex, synaptic vesicle PDZ domain binding, beta-amyloid binding, phosphatidylinositol-4,5-bisphosphate binding, protein binding, protein complex binding Human UniProtKB:P05067 APBA2 PINC UniProtKB {GO:0005515=PMID:10833507, GO:0010468=GO_REF:0000019, GO:0001540=GO_REF:0000019, GO:0035264=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0007268=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0001701=GO_REF:0000019, GO:0007399=PMID:9890987} Q99767 Amyloid beta A4 precursor protein-binding family A member 2 protein 20030904 {GO:0005515=IPI, GO:0010468=IEA, GO:0001540=IEA, GO:0035264=IEA, GO:0005886=IEA, GO:0007268=IEA, GO:0007626=IEA, GO:0015031=IEA, GO:0001701=IEA, GO:0007399=TAS} in utero embryonic development, locomotory behavior, multicellular organism growth, nervous system development, protein transport, regulation of gene expression, synaptic transmission plasma membrane beta-amyloid binding, protein binding Human APBA3 IntAct UniProtKB {GO:0004857=PMID:19726677, GO:0035556=GO_REF:0000029, GO:0005515=PMID:21903422, GO:0010468=GO_REF:0000019, GO:0048471=PMID:19726677, GO:0001540=GO_REF:0000019, GO:0016020=GO_REF:0000029, GO:0007268=GO_REF:0000019, GO:0019899=PMID:19726677, GO:0015031=GO_REF:0000037, GO:0043086=PMID:19726677, GO:0001701=GO_REF:0000019} O96018 Amyloid beta A4 precursor protein-binding family A member 3 protein 20130415 {GO:0004857=IDA, GO:0035556=NAS, GO:0005515=IPI, GO:0010468=IEA, GO:0048471=IDA, GO:0001540=IEA, GO:0016020=NAS, GO:0007268=IEA, GO:0019899=IPI, GO:0015031=IEA, GO:0043086=IDA, GO:0001701=IEA} in utero embryonic development, intracellular signal transduction, negative regulation of catalytic activity, protein transport, regulation of gene expression, synaptic transmission membrane, perinuclear region of cytoplasm beta-amyloid binding, enzyme binding, enzyme inhibitor activity, protein binding Human UniProtKB:Q9QYP6 APBB1 IntAct UniProtKB {GO:0005515=PMID:16049941, GO:0030308=GO_REF:0000024, GO:0005886=PMID:18468999, GO:0045202=PMID:12843239, GO:0005634=PMID:19343227, GO:0045739=GO_REF:0000019, GO:0007409=PMID:12843239, GO:0006302=GO_REF:0000019, GO:0030426=PMID:12843239, GO:0042393=PMID:19234442, GO:0005737=PMID:18468999, GO:0001540=PMID:18468999, GO:0030198=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0007050=GO_REF:0000024, GO:0050760=GO_REF:0000024, GO:0070064=PMID:17686488, GO:0006355=GO_REF:0000024, GO:0043065=PMID:18468999, GO:0006915=GO_REF:0000037, GO:0045749=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0030027=PMID:12843239, GO:0006974=PMID:18468999, GO:0007165=PMID:8894693, GO:0016607=GO_REF:0000039, GO:0045665=GO_REF:0000019, GO:0043967=GO_REF:0000024, GO:0003682=PMID:19343227, GO:0008542=GO_REF:0000019, GO:0045893=PMID:19343227, GO:0001764=GO_REF:0000019, GO:0008134=GO_REF:0000024} O00213 Amyloid beta A4 precursor protein-binding family B member 1 protein 20130415 {GO:0005515=IPI, GO:0030308=ISS, GO:0005886=IDA, GO:0045202=IDA, GO:0005634=IDA, GO:0045739=IEA, GO:0007409=NAS, GO:0006302=IEA, GO:0030426=IDA, GO:0042393=IPI, GO:0005737=IDA, GO:0001540=IPI, GO:0030198=IEA, GO:0007411=IEA, GO:0007050=ISS, GO:0050760=ISS, GO:0070064=IPI, GO:0006355=ISS, GO:0043065=IDA, GO:0006915=IEA, GO:0045749=ISS, GO:0006351=IEA, GO:0030027=IDA, GO:0006974=IDA, GO:0007165=NAS, GO:0016607=IEA, GO:0045665=IEA, GO:0043967=ISS, GO:0003682=IDA, GO:0008542=IEA, GO:0045893=IDA, GO:0001764=IEA, GO:0008134=ISS} apoptotic process, axon guidance, axonogenesis, cell cycle arrest, double-strand break repair, extracellular matrix organization, histone H4 acetylation, negative regulation of S phase of mitotic cell cycle, negative regulation of cell growth, negative regulation of neuron differentiation, negative regulation of thymidylate synthase biosynthetic process, neuron migration, positive regulation of DNA repair, positive regulation of apoptotic process, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, response to DNA damage stimulus, signal transduction, transcription, DNA-dependent, visual learning cytoplasm, growth cone, lamellipodium, nuclear speck, nucleus, plasma membrane, synapse beta-amyloid binding, chromatin binding, histone binding, proline-rich region binding, protein binding, transcription factor binding Human UniProtKB:P05067 APBB1IP InterPro UniProtKB {GO:0007165=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0007596=Reactome:REACT_604, GO:0030168=Reactome:REACT_798, GO:0005856=GO_REF:0000039, GO:0005925=GO_REF:0000039, GO:0030027=GO_REF:0000039, GO:0005829=Reactome:REACT_23931} Q9NWJ6 cDNA FLJ20805 fis, clone ADSE02009 protein 20130413 {GO:0007165=IEA, GO:0005543=IEA, GO:0005886=IEA, GO:0007596=TAS, GO:0030168=TAS, GO:0005856=IEA, GO:0005925=IEA, GO:0030027=IEA, GO:0005829=TAS} blood coagulation, platelet activation, signal transduction cytoskeleton, cytosol, focal adhesion, lamellipodium, plasma membrane phospholipid binding Human InterPro:IPR000159 APBB2 IntAct UniProtKB {GO:0005515=PMID:8855266, GO:0006355=GO_REF:0000024, GO:0030308=GO_REF:0000024, GO:0043066=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0045202=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0030027=GO_REF:0000024, GO:0045749=GO_REF:0000024, GO:0030426=GO_REF:0000024, GO:0035556=PMID:8855266, GO:0005737=GO_REF:0000019, GO:0001540=GO_REF:0000024, GO:0016020=PMID:8855266, GO:0007411=GO_REF:0000019, GO:0030198=GO_REF:0000019, GO:0007050=GO_REF:0000024, GO:0001764=GO_REF:0000019, GO:0008134=GO_REF:0000024} Q92870 Amyloid beta A4 precursor protein-binding family B member 2 protein 20130415 {GO:0005515=IPI, GO:0006355=ISS, GO:0030308=ISS, GO:0043066=IEA, GO:0043065=IEA, GO:0045202=ISS, GO:0005634=ISS, GO:0030027=ISS, GO:0045749=ISS, GO:0030426=ISS, GO:0035556=NAS, GO:0005737=IEA, GO:0001540=ISS, GO:0016020=NAS, GO:0007411=IEA, GO:0030198=IEA, GO:0007050=ISS, GO:0001764=IEA, GO:0008134=ISS} axon guidance, cell cycle arrest, extracellular matrix organization, intracellular signal transduction, negative regulation of S phase of mitotic cell cycle, negative regulation of apoptotic process, negative regulation of cell growth, neuron migration, positive regulation of apoptotic process, regulation of transcription, DNA-dependent cytoplasm, growth cone, lamellipodium, membrane, nucleus, synapse beta-amyloid binding, protein binding, transcription factor binding Human UniProtKB:P05067 APBB3 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0015629=GO_REF:0000052} O95704 Amyloid beta A4 precursor protein-binding family B member 3 protein 20080818 {GO:0005737=IDA, GO:0015629=IDA} actin cytoskeleton, cytoplasm Human APC BHF-UCL UniProtKB {GO:0008017=PMID:16188939, GO:0005515=PMID:22682247, GO:0009798=GO_REF:0000019, GO:0008013=PMID:7890674, GO:0051171=GO_REF:0000019, GO:0060041=GO_REF:0000019, GO:0030877=PMID:16188939, GO:0031122=GO_REF:0000019, GO:0035371=GO_REF:0000019, GO:0048538=GO_REF:0000019, GO:0007409=GO_REF:0000019, GO:0070830=PMID:18502210, GO:0051010=PMID:19632184, GO:0031274=PMID:17192415, GO:0051781=GO_REF:0000019, GO:0016055=GO_REF:0000002, GO:0001942=GO_REF:0000019, GO:0005813=PMID:11283619, GO:0033077=GO_REF:0000019, GO:0045296=PMID:7890674, GO:0030335=PMID:17192415, GO:0045295=PMID:7890674, GO:0019901=PMID:8638126, GO:0000281=PMID:17570218, GO:0030027=PMID:19151759, GO:0045785=GO_REF:0000019, GO:0000776=PMID:11283619, GO:0043588=GO_REF:0000019, GO:0005923=PMID:18502210, GO:0060770=GO_REF:0000019, GO:0007094=PMID:17227893, GO:0005881=GO_REF:0000019, GO:0045732=PMID:16188939, GO:0051276=GO_REF:0000019, GO:0008285=PMID:8521819, GO:0005886=PMID:16611247, GO:0042483=GO_REF:0000019, GO:0045736=PMID:8521819, GO:0030178=GO_REF:0000002, GO:0009954=GO_REF:0000019, GO:0005634=PMID:12072559, GO:0009953=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0006921=Reactome:REACT_995, GO:0046716=GO_REF:0000019, GO:0005829=Reactome:REACT_12012, GO:0019887=PMID:11972058, GO:0043409=GO_REF:0000019, GO:0030858=GO_REF:0000019, GO:0005737=PMID:20937854, GO:0005913=PMID:16611247, GO:0007050=PMID:8521819, GO:0007155=PMID:8259518, GO:0090090=PMID:12952940, GO:0060070=PMID:9601641, GO:0007091=GO_REF:0000019, GO:0035019=GO_REF:0000019, GO:0031253=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0031116=GO_REF:0000019, GO:0043065=PMID:17227893, GO:0001822=GO_REF:0000019, GO:0051988=PMID:17227893, GO:0006915=Reactome:REACT_578, GO:0032886=PMID:20937854, GO:0032587=PMID:19151759, GO:0045670=GO_REF:0000019, GO:0044295=GO_REF:0000019, GO:0016328=PMID:12072559, GO:0006974=PMID:14728717, GO:0045667=GO_REF:0000019, GO:0006461=PMID:16188939, GO:0016477=PMID:19151759, GO:0007026=PMID:17192415} P25054 Adenomatous polyposis coli protein protein 20100825 {GO:0008017=IDA, GO:0005515=IPI, GO:0009798=IEA, GO:0008013=IPI, GO:0051171=IEA, GO:0060041=IEA, GO:0030877=IDA, GO:0031122=IEA, GO:0035371=IEA, GO:0048538=IEA, GO:0007409=IEA, GO:0070830=NAS, GO:0051010=IDA, GO:0031274=IMP, GO:0051781=IEA, GO:0016055=IEA, GO:0001942=IEA, GO:0005813=IDA, GO:0033077=IEA, GO:0045296=IDA, GO:0030335=IMP, GO:0045295=IPI, GO:0019901=IPI, GO:0000281=IMP, GO:0030027=IDA, GO:0045785=IEA, GO:0000776=IDA, GO:0043588=IEA, GO:0005923=IDA, GO:0060770=IEA, GO:0007094=IMP, GO:0005881=IEA, GO:0045732=IC, GO:0051276=IEA, GO:0008285=IDA, GO:0005886=IDA, GO:0042483=IEA, GO:0045736=IDA, GO:0030178=IEA, GO:0009954=IEA, GO:0005634=IDA, GO:0009953=IEA, GO:0009952=IEA, GO:0006921=TAS, GO:0046716=IEA, GO:0005829=TAS, GO:0019887=IDA, GO:0043409=IEA, GO:0030858=IEA, GO:0005737=IDA, GO:0005913=IDA, GO:0007050=IDA, GO:0007155=NAS, GO:0090090=IGI, GO:0060070=IC, GO:0007091=IEA, GO:0035019=IEA, GO:0031253=IEA, GO:0043066=IEA, GO:0031116=IEA, GO:0043065=IMP, GO:0001822=IEA, GO:0051988=IMP, GO:0006915=TAS, GO:0032886=IMP, GO:0032587=IDA, GO:0045670=IEA, GO:0044295=IEA, GO:0016328=IDA, GO:0006974=IDA, GO:0045667=IEA, GO:0006461=IDA, GO:0016477=IMP, GO:0007026=IMP} T cell differentiation in thymus, Wnt receptor signaling pathway, anterior/posterior pattern specification, apoptotic process, axis specification, axonogenesis, canonical Wnt receptor signaling pathway, cell adhesion, cell cycle arrest, cell migration, cellular component disassembly involved in execution phase of apoptosis, chromosome organization, cytokinesis after mitosis, cytoplasmic microtubule organization, dorsal/ventral pattern formation, hair follicle development, kidney development, metaphase/anaphase transition of mitotic cell cycle, mitotic spindle assembly checkpoint, muscle cell homeostasis, negative regulation of MAPK cascade, negative regulation of Wnt receptor signaling pathway, negative regulation of apoptotic process, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cell proliferation, negative regulation of cyclin-dependent protein serine/threonine kinase activity, negative regulation of epithelial cell proliferation involved in prostate gland development, negative regulation of microtubule depolymerization, negative regulation of odontogenesis, positive regulation of apoptotic process, positive regulation of cell adhesion, positive regulation of cell division, positive regulation of cell migration, positive regulation of epithelial cell differentiation, positive regulation of microtubule polymerization, positive regulation of protein catabolic process, positive regulation of pseudopodium assembly, protein complex assembly, proximal/distal pattern formation, regulation of attachment of spindle microtubules to kinetochore, regulation of microtubule-based process, regulation of nitrogen compound metabolic process, regulation of osteoblast differentiation, regulation of osteoclast differentiation, response to DNA damage stimulus, retina development in camera-type eye, skin development, somatic stem cell maintenance, thymus development, tight junction assembly axonal growth cone, beta-catenin destruction complex, cell projection membrane, cell-cell adherens junction, centrosome, cytoplasm, cytoplasmic microtubule, cytosol, kinetochore, lamellipodium, lateral plasma membrane, microtubule plus end, nucleus, plasma membrane, ruffle membrane, tight junction beta-catenin binding, cadherin binding, gamma-catenin binding, microtubule binding, microtubule plus-end binding, protein binding, protein kinase binding, protein kinase regulator activity colocalizes_with Human APC2 BHF-UCL UniProtKB {GO:0008017=GO_REF:0000002, GO:0005515=PMID:10646860, GO:0005881=PMID:11691822, GO:0048471=PMID:10646860, GO:0005794=PMID:11691822, GO:0031258=PMID:11691822, GO:0008013=PMID:9823329, GO:0005884=PMID:11691822, GO:0016342=PMID:9823329, GO:0035414=PMID:10021369, GO:0005737=PMID:11691822, GO:0000139=GO_REF:0000039, GO:0016055=GO_REF:0000037, GO:0090090=PMID:10021369} O95996 Adenomatous polyposis coli protein 2 protein 20101014 {GO:0008017=IEA, GO:0005515=IPI, GO:0005881=IMP, GO:0048471=IDA, GO:0005794=IDA, GO:0031258=IDA, GO:0008013=IDA, GO:0005884=IDA, GO:0016342=IDA, GO:0035414=IDA, GO:0005737=IDA, GO:0000139=IEA, GO:0016055=IEA, GO:0090090=IDA} Wnt receptor signaling pathway, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of catenin import into nucleus Golgi apparatus, Golgi membrane, actin filament, catenin complex, cytoplasm, cytoplasmic microtubule, lamellipodium membrane, perinuclear region of cytoplasm beta-catenin binding, microtubule binding, protein binding Human APCDD1 UniProtKB UniProtKB {GO:0017147=PMID:20393562, GO:0005887=PMID:20393562, GO:0030178=PMID:20393562, GO:0016055=GO_REF:0000037, GO:0001942=PMID:20393562} Q8J025 Protein APCDD1 protein 20100423 {GO:0017147=IDA, GO:0005887=IDA, GO:0030178=IDA, GO:0016055=IEA, GO:0001942=IMP} Wnt receptor signaling pathway, hair follicle development, negative regulation of Wnt receptor signaling pathway integral to plasma membrane Wnt-protein binding Human APCS Reactome UniProtKB {GO:0043234=GO_REF:0000019, GO:0006457=PMID:10812074, GO:0005576=Reactome:REACT_75905, GO:0051082=PMID:10812074, GO:0006953=PMID:2987268, GO:0051131=PMID:10972085, GO:0046872=GO_REF:0000037} P02743 Serum amyloid P-component protein 20101013 {GO:0043234=IEA, GO:0006457=TAS, GO:0005576=TAS, GO:0051082=TAS, GO:0006953=TAS, GO:0051131=TAS, GO:0046872=IEA} acute-phase response, chaperone-mediated protein complex assembly, protein folding extracellular region, protein complex metal ion binding, unfolded protein binding Human APEH HPA UniProtKB {GO:0031965=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0004252=GO_REF:0000002, GO:0006508=GO_REF:0000002} P13798 Acylamino-acid-releasing enzyme protein 20101115 {GO:0031965=IDA, GO:0005737=IDA, GO:0004252=IEA, GO:0006508=IEA} proteolysis cytoplasm, nuclear membrane serine-type endopeptidase activity Human APEX1 GOC UniProtKB {GO:0005515=PMID:20856196, GO:0003906=PMID:19188445, GO:0004844=PMID:10805771, GO:0008408=PMID:11832948, GO:0070301=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0005622=GO_REF:0000002, GO:0004528=PMID:9119221, GO:0004523=PMID:11286553, GO:0080111=PMID:21496894, GO:0043488=PMID:19401441, GO:0005813=GO_REF:0000052, GO:0008081=PMID:11478795, GO:0003714=PMID:7961715, GO:0007568=GO_REF:0000019, GO:0003713=PMID:9119221, GO:0004520=PMID:1722334, GO:0004521=GO_REF:0000019, GO:0031490=PMID:11809897, GO:0004519=PMID:11478795, GO:0006281=Reactome:REACT_216, GO:0006284=Reactome:REACT_1104, GO:0016491=PMID:12524539, GO:0045750=GO_REF:0000019, GO:0045454=GO_REF:0000019, GO:0005654=Reactome:REACT_2224, GO:0055114=PMID:9119221, GO:0048471=PMID:12524539, GO:0016890=PMID:19188445, GO:0005783=PMID:12524539, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0045739=PMID:9207062, GO:0014912=GO_REF:0000019, GO:0046872=PMID:11286553, GO:0005739=PMID:20231292, GO:0005737=PMID:9560228, GO:0071375=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0051059=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0005730=PMID:17148573, GO:0006310=GO_REF:0000037, GO:0003677=PMID:11286553, GO:0006351=GO_REF:0000037, GO:0003684=PMID:12524539, GO:0016607=PMID:17148573, GO:0005840=PMID:12524539, GO:0071320=GO_REF:0000019} P27695 DNA-(apurinic or apyrimidinic site) lyase protein 20130413 {GO:0005515=IPI, GO:0003906=IDA, GO:0004844=TAS, GO:0008408=IDA, GO:0070301=IEA, GO:0032403=IEA, GO:0005622=IEA, GO:0004528=TAS, GO:0004523=TAS, GO:0080111=IDA, GO:0043488=IMP, GO:0005813=IDA, GO:0008081=IDA, GO:0003714=TAS, GO:0007568=IEA, GO:0003713=IDA, GO:0004520=TAS, GO:0004521=IEA, GO:0031490=IDA, GO:0004519=IDA, GO:0006281=TAS, GO:0006284=TAS, GO:0016491=IDA, GO:0045750=IEA, GO:0045454=IEA, GO:0005654=TAS, GO:0055114=IDA, GO:0048471=IDA, GO:0016890=IDA, GO:0005783=TAS, GO:0003723=IEA, GO:0005634=IDA, GO:0045739=IDA, GO:0014912=IEA, GO:0046872=IDA, GO:0005739=IDA, GO:0005737=IDA, GO:0071375=IEA, GO:0005667=IEA, GO:0006355=IEA, GO:0051059=IEA, GO:0042493=IEA, GO:0005730=IDA, GO:0006310=IEA, GO:0003677=IDA, GO:0006351=IEA, GO:0003684=IDA, GO:0016607=IDA, GO:0005840=TAS, GO:0071320=IEA} DNA demethylation, DNA recombination, DNA repair, aging, base-excision repair, cell redox homeostasis, cellular response to cAMP, cellular response to hydrogen peroxide, cellular response to peptide hormone stimulus, negative regulation of smooth muscle cell migration, oxidation-reduction process, positive regulation of DNA repair, positive regulation of S phase of mitotic cell cycle, regulation of mRNA stability, regulation of transcription, DNA-dependent, response to drug, transcription, DNA-dependent centrosome, cytoplasm, endoplasmic reticulum, intracellular, mitochondrion, nuclear speck, nucleolus, nucleoplasm, nucleus, perinuclear region of cytoplasm, ribosome, transcription factor complex 3'-5' exonuclease activity, DNA binding, DNA-(apurinic or apyrimidinic site) lyase activity, NF-kappaB binding, RNA binding, chromatin DNA binding, damaged DNA binding, endodeoxyribonuclease activity, endonuclease activity, endoribonuclease activity, metal ion binding, oxidoreductase activity, phosphodiesterase I activity, phosphoric diester hydrolase activity, protein binding, protein complex binding, ribonuclease H activity, site-specific endodeoxyribonuclease activity, specific for altered base, transcription coactivator activity, transcription corepressor activity, uracil DNA N-glycosylase activity Human APEX2 UniProtKB UniProtKB {GO:0003906=GO_REF:0000003, GO:0007049=GO_REF:0000037, GO:0004527=GO_REF:0000037, GO:0006281=GO_REF:0000037, GO:0004519=GO_REF:0000037, GO:0005743=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0006310=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037} Q9UBZ4 DNA-(apurinic or apyrimidinic site) lyase 2 protein 20130413 {GO:0003906=IEA, GO:0007049=IEA, GO:0004527=IEA, GO:0006281=IEA, GO:0004519=IEA, GO:0005743=IEA, GO:0005634=IEA, GO:0006310=IEA, GO:0008270=IEA, GO:0003677=IEA} DNA recombination, DNA repair, cell cycle mitochondrial inner membrane, nucleus DNA binding, DNA-(apurinic or apyrimidinic site) lyase activity, endonuclease activity, exonuclease activity, zinc ion binding Human UniProtKB-SubCell:SL-0191 APH1A Reactome UniProtKB {GO:0001656=GO_REF:0000019, GO:0005515=PMID:12297508, GO:0042987=PMID:15274632, GO:0048011=Reactome:REACT_13776, GO:0007220=Reactome:REACT_691, GO:0005794=PMID:15274632, GO:0005886=Reactome:REACT_160171, GO:0031293=Reactome:REACT_13443, GO:0005783=PMID:15274632, GO:0006915=Reactome:REACT_13643, GO:0043085=PMID:15274632, GO:0097190=Reactome:REACT_13720, GO:0007219=Reactome:REACT_118862, GO:0004175=GO_REF:0000019, GO:0005887=PMID:15274632, GO:0016485=PMID:15274632, GO:0032580=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0006509=PMID:15274632, GO:0016021=GO_REF:0000002} Q96BI3 Gamma-secretase subunit APH-1A protein 20130301 {GO:0001656=IEA, GO:0005515=IPI, GO:0042987=TAS, GO:0048011=TAS, GO:0007220=TAS, GO:0005794=IDA, GO:0005886=TAS, GO:0031293=TAS, GO:0005783=IDA, GO:0006915=TAS, GO:0043085=IDA, GO:0097190=TAS, GO:0007219=TAS, GO:0004175=IEA, GO:0005887=IDA, GO:0016485=IDA, GO:0032580=IEA, GO:0005789=IEA, GO:0006509=IDA, GO:0016021=IEA} Notch receptor processing, Notch signaling pathway, amyloid precursor protein catabolic process, apoptotic process, apoptotic signaling pathway, membrane protein ectodomain proteolysis, membrane protein intracellular domain proteolysis, metanephros development, neurotrophin TRK receptor signaling pathway, positive regulation of catalytic activity, protein processing Golgi apparatus, Golgi cisterna membrane, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, integral to plasma membrane, plasma membrane endopeptidase activity, protein binding Human APH1B Reactome UniProtKB {GO:0005515=PMID:12297508, GO:0030133=GO_REF:0000054, GO:0048011=Reactome:REACT_13776, GO:0007220=Reactome:REACT_691, GO:0005886=Reactome:REACT_160171, GO:0031293=Reactome:REACT_13443, GO:0006915=Reactome:REACT_13643, GO:0043085=GO_REF:0000002, GO:0097190=Reactome:REACT_13720, GO:0007219=Reactome:REACT_118862, GO:0016485=PMID:12297508, GO:0008233=PMID:12297508, GO:0016021=PMID:12297508} Q8WW43 Gamma-secretase subunit APH-1B protein 20130301 {GO:0005515=IPI, GO:0030133=IDA, GO:0048011=TAS, GO:0007220=TAS, GO:0005886=TAS, GO:0031293=TAS, GO:0006915=TAS, GO:0043085=IEA, GO:0097190=TAS, GO:0007219=TAS, GO:0016485=IDA, GO:0008233=IDA, GO:0016021=IDA} Notch receptor processing, Notch signaling pathway, apoptotic process, apoptotic signaling pathway, membrane protein intracellular domain proteolysis, neurotrophin TRK receptor signaling pathway, positive regulation of catalytic activity, protein processing integral to membrane, plasma membrane, transport vesicle peptidase activity, protein binding Human API5 HPA UniProtKB {GO:0005737=PMID:11075807, GO:0043066=PMID:10780674, GO:0017134=PMID:11075807, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0005681=PMID:11555636, GO:0005634=GO_REF:0000052} Q9BZZ5 Apoptosis inhibitor 5 protein 20100326 {GO:0005737=NAS, GO:0043066=NAS, GO:0017134=IPI, GO:0005730=IDA, GO:0006915=IEA, GO:0005681=ISS, GO:0005634=IDA} apoptotic process, negative regulation of apoptotic process cytoplasm, nucleolus, nucleus, spliceosomal complex fibroblast growth factor binding NOT Human APIP IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0043066=PMID:22837397, GO:0006915=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0042802=PMID:19060904, GO:0005829=Reactome:REACT_75828, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000002, GO:0000096=Reactome:REACT_115639, GO:0019509=Reactome:REACT_75881, GO:0006595=Reactome:REACT_14820, GO:0070372=GO_REF:0000024, GO:0046570=Reactome:REACT_75828} Q96GX9 Methylthioribulose-1-phosphate dehydratase protein 20130415 {GO:0005515=IPI, GO:0043066=IMP, GO:0006915=IEA, GO:0044281=TAS, GO:0046872=IEA, GO:0042802=IPI, GO:0005829=TAS, GO:0034641=TAS, GO:0005737=IEA, GO:0000096=TAS, GO:0019509=TAS, GO:0006595=TAS, GO:0070372=ISS, GO:0046570=TAS} L-methionine salvage from methylthioadenosine, apoptotic process, cellular nitrogen compound metabolic process, negative regulation of apoptotic process, polyamine metabolic process, regulation of ERK1 and ERK2 cascade, small molecule metabolic process, sulfur amino acid metabolic process cytoplasm, cytosol identical protein binding, metal ion binding, methylthioribulose 1-phosphate dehydratase activity, protein binding Human UniProtKB:Q96GX9 APITD1 IntAct UniProtKB {GO:0005515=PMID:22304917, GO:0000236=Reactome:REACT_682, GO:0006352=GO_REF:0000002, GO:0071821=PMID:20347428, GO:0046982=GO_REF:0000002, GO:0003677=PMID:20347429, GO:0006974=PMID:20347428, GO:0005829=Reactome:REACT_150414, GO:0043240=PMID:20347428, GO:0003690=PMID:20347428, GO:0006281=PMID:20347429, GO:0003682=PMID:20347429, GO:0000712=PMID:20347428, GO:0000087=Reactome:REACT_910, GO:0031398=PMID:20347428, GO:0000777=GO_REF:0000039, GO:0031297=PMID:20347428, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q8N2Z9 Centromere protein S protein 20130415 {GO:0005515=IPI, GO:0000236=TAS, GO:0006352=IEA, GO:0071821=IDA, GO:0046982=IEA, GO:0003677=IDA, GO:0006974=IMP, GO:0005829=TAS, GO:0043240=IDA, GO:0003690=IDA, GO:0006281=IDA, GO:0003682=IDA, GO:0000712=IMP, GO:0000087=TAS, GO:0031398=TAS, GO:0000777=IEA, GO:0031297=IMP, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} DNA repair, DNA-dependent transcription, initiation, M phase of mitotic cell cycle, cell division, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, positive regulation of protein ubiquitination, replication fork processing, resolution of meiotic recombination intermediates, response to DNA damage stimulus FANCM-MHF complex, Fanconi anaemia nuclear complex, condensed chromosome kinetochore, cytosol DNA binding, chromatin binding, double-stranded DNA binding, protein binding, protein heterodimerization activity Human UniProtKB:A8MT69 APLF UniProtKB UniProtKB {GO:0003906=PMID:17396150, GO:0005515=PMID:17396150, GO:0000012=PMID:17396150, GO:0008408=PMID:17396150, GO:0000166=PMID:18172500, GO:0004520=PMID:17396150, GO:0005634=PMID:17396150, GO:0006974=PMID:17396150, GO:0046872=GO_REF:0000037, GO:0006302=PMID:17396150, GO:0005829=GO_REF:0000039} Q8IW19 Aprataxin and PNK-like factor protein 20090814 {GO:0003906=IDA, GO:0005515=IPI, GO:0000012=IMP, GO:0008408=IDA, GO:0000166=IDA, GO:0004520=IDA, GO:0005634=IDA, GO:0006974=IDA, GO:0046872=IEA, GO:0006302=IMP, GO:0005829=IEA} double-strand break repair, response to DNA damage stimulus, single strand break repair cytosol, nucleus 3'-5' exonuclease activity, DNA-(apurinic or apyrimidinic site) lyase activity, endodeoxyribonuclease activity, metal ion binding, nucleotide binding, protein binding Human UniProtKB:P09874 APLN Reactome UniProtKB {GO:0048471=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0005102=PMID:9792798, GO:0005576=Reactome:REACT_22289, GO:0045776=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0031704=GO_REF:0000019, GO:0007165=GO_REF:0000002, GO:0006955=PMID:10525157, GO:0043576=GO_REF:0000019, GO:0007595=PMID:10525157, GO:0005179=GO_REF:0000037, GO:0042756=GO_REF:0000019, GO:0045906=GO_REF:0000019, GO:0002026=GO_REF:0000019, GO:0045909=GO_REF:0000019, GO:0051461=GO_REF:0000019, GO:0031652=GO_REF:0000019, GO:0051466=GO_REF:0000019, GO:0042327=GO_REF:0000019} Q9ULZ1 Apelin protein 20080729 {GO:0048471=IEA, GO:0008284=IEA, GO:0005102=TAS, GO:0005576=TAS, GO:0045776=IEA, GO:0005615=IEA, GO:0031704=IEA, GO:0007165=IEA, GO:0006955=TAS, GO:0043576=IEA, GO:0007595=TAS, GO:0005179=IEA, GO:0042756=IEA, GO:0045906=IEA, GO:0002026=IEA, GO:0045909=IEA, GO:0051461=IEA, GO:0031652=IEA, GO:0051466=IEA, GO:0042327=IEA} drinking behavior, immune response, lactation, negative regulation of blood pressure, negative regulation of vasoconstriction, positive regulation of cell proliferation, positive regulation of corticotropin secretion, positive regulation of corticotropin-releasing hormone secretion, positive regulation of heat generation, positive regulation of phosphorylation, positive regulation of vasodilation, regulation of respiratory gaseous exchange, regulation of the force of heart contraction, signal transduction extracellular region, extracellular space, perinuclear region of cytoplasm apelin receptor binding, hormone activity, receptor binding Human APLNR Reactome UniProtKB {GO:0005886=Reactome:REACT_22289, GO:0007186=PMID:9792798, GO:0005887=PMID:8294032, GO:0004930=GO_REF:0000037, GO:0004872=PMID:9792798, GO:0050878=GO_REF:0000019} P35414 Apelin receptor protein 20080728 {GO:0005886=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0004930=IEA, GO:0004872=TAS, GO:0050878=IEA} G-protein coupled receptor signaling pathway, regulation of body fluid levels integral to plasma membrane, plasma membrane G-protein coupled receptor activity, receptor activity Human APLP1 BHF-UCL UniProtKB {GO:0005515=PMID:16193067, GO:0006378=GO_REF:0000019, GO:0048471=PMID:16531006, GO:0005794=GO_REF:0000019, GO:0005886=PMID:16531006, GO:0030818=PMID:16531006, GO:0046914=GO_REF:0000002, GO:0006915=GO_REF:0000037, GO:0031696=PMID:16531006, GO:0007193=PMID:16531006, GO:0031695=PMID:16531006, GO:0031694=PMID:16531006, GO:0006417=GO_REF:0000019, GO:0005604=PMID:9521588, GO:0006897=GO_REF:0000037, GO:0007399=PMID:9521588, GO:0042802=PMID:16193067, GO:0030198=GO_REF:0000019, GO:0009887=PMID:9521588, GO:0071874=PMID:16531006, GO:0016021=GO_REF:0000037, GO:0030900=GO_REF:0000019, GO:0007155=GO_REF:0000037, GO:0008201=GO_REF:0000037} P51693 Amyloid-like protein 1 protein 20110110 {GO:0005515=IPI, GO:0006378=IEA, GO:0048471=IDA, GO:0005794=IEA, GO:0005886=IDA, GO:0030818=IDA, GO:0046914=IEA, GO:0006915=IEA, GO:0031696=IPI, GO:0007193=IC, GO:0031695=IPI, GO:0031694=IPI, GO:0006417=IEA, GO:0005604=TAS, GO:0006897=IEA, GO:0007399=TAS, GO:0042802=IPI, GO:0030198=IEA, GO:0009887=TAS, GO:0071874=IDA, GO:0016021=IEA, GO:0030900=IEA, GO:0007155=IEA, GO:0008201=IEA} adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, apoptotic process, cell adhesion, cellular response to norepinephrine stimulus, endocytosis, extracellular matrix organization, forebrain development, mRNA polyadenylation, negative regulation of cAMP biosynthetic process, nervous system development, organ morphogenesis, regulation of translation Golgi apparatus, basement membrane, integral to membrane, perinuclear region of cytoplasm, plasma membrane alpha-2A adrenergic receptor binding, alpha-2B adrenergic receptor binding, alpha-2C adrenergic receptor binding, heparin binding, identical protein binding, protein binding, transition metal ion binding Human APLP2 ENSEMBL UniProtKB {GO:0005515=PMID:20936779, GO:0005886=GO_REF:0000039, GO:0004867=GO_REF:0000037, GO:0007617=GO_REF:0000019, GO:0046914=GO_REF:0000002, GO:0043393=GO_REF:0000019, GO:0005634=PMID:7702756, GO:0009790=GO_REF:0000019, GO:0003677=PMID:7702756, GO:0042802=PMID:16193067, GO:0001967=GO_REF:0000019, GO:0006878=GO_REF:0000019, GO:0007186=PMID:8220435, GO:0030198=GO_REF:0000019, GO:0007176=GO_REF:0000019, GO:0050885=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0030901=GO_REF:0000019, GO:0016021=PMID:8485127, GO:0030900=GO_REF:0000019, GO:0008201=GO_REF:0000002, GO:0008203=GO_REF:0000019} Q9UED0 Amyloid-like protein 2 protein 20130413 {GO:0005515=IPI, GO:0005886=IEA, GO:0004867=IEA, GO:0007617=IEA, GO:0046914=IEA, GO:0043393=IEA, GO:0005634=IDA, GO:0009790=IEA, GO:0003677=NAS, GO:0042802=IPI, GO:0001967=IEA, GO:0006878=IEA, GO:0007186=NAS, GO:0030198=IEA, GO:0007176=IEA, GO:0050885=IEA, GO:0007626=IEA, GO:0030901=IEA, GO:0016021=NAS, GO:0030900=IEA, GO:0008201=IEA, GO:0008203=IEA} G-protein coupled receptor signaling pathway, cellular copper ion homeostasis, cholesterol metabolic process, embryo development, extracellular matrix organization, forebrain development, locomotory behavior, mating behavior, midbrain development, neuromuscular process controlling balance, regulation of epidermal growth factor-activated receptor activity, regulation of protein binding, suckling behavior integral to membrane, nucleus, plasma membrane DNA binding, heparin binding, identical protein binding, protein binding, serine-type endopeptidase inhibitor activity, transition metal ion binding Human Ensembl:ENSMUSP00000072428 APOA1 BHF-UCL UniProtKB {GO:0005515=PMID:12084722, GO:0006695=GO_REF:0000019, GO:0043627=GO_REF:0000019, GO:0007603=Reactome:REACT_160125, GO:0019915=GO_REF:0000019, GO:0060192=GO_REF:0000019, GO:0030300=GO_REF:0000019, GO:0018206=PMID:12576517, GO:0010903=PMID:14967812, GO:0030301=PMID:10559507, GO:0005615=PMID:22261194, GO:0042802=PMID:8049247, GO:0034361=PMID:17154273, GO:0034364=PMID:21571275, GO:0034115=PMID:21571275, GO:0055102=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0006656=PMID:4335615, GO:0042632=PMID:21571275, GO:0033344=PMID:11162594, GO:0060761=PMID:21571275, GO:0051345=PMID:7638166, GO:0043691=PMID:15464323, GO:0034366=PMID:16682745, GO:0030168=Reactome:REACT_798, GO:0051347=GO_REF:0000019, GO:0005548=GO_REF:0000019, GO:0010804=PMID:21571275, GO:0070508=PMID:14718538, GO:0043534=GO_REF:0000019, GO:0007186=PMID:16443932, GO:0034375=PMID:4335615, GO:0042157=Reactome:REACT_13621, GO:0055091=PMID:21571275, GO:0005788=Reactome:REACT_6915, GO:0019899=PMID:1587806, GO:0034774=Reactome:REACT_21324, GO:0042158=GO_REF:0000019, GO:0008035=GO_REF:0000019, GO:0006629=Reactome:REACT_602, GO:0030325=GO_REF:0000019, GO:0005886=Reactome:REACT_15367, GO:0031100=GO_REF:0000019, GO:0017127=PMID:9651324, GO:0010873=PMID:4335615, GO:0070328=PMID:21571275, GO:0050713=PMID:12458630, GO:0030139=PMID:14747463, GO:0005634=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0060228=PMID:4335615, GO:0005829=Reactome:REACT_160215, GO:0008289=GO_REF:0000002, GO:0002740=PMID:12458630, GO:0034384=PMID:12651854, GO:0005543=PMID:12810715, GO:0001540=PMID:11297421, GO:0034191=PMID:16443932, GO:0015485=PMID:15464323, GO:0014012=GO_REF:0000019, GO:0034190=PMID:11162594, GO:0034380=PMID:190223, GO:0018158=PMID:12576517, GO:0070653=PMID:10764676, GO:0008203=PMID:15464323, GO:0032489=PMID:16443932, GO:0007584=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0050821=PMID:17655203, GO:0005576=Reactome:REACT_160272, GO:0031410=PMID:14703508, GO:0001523=Reactome:REACT_24968, GO:0055085=Reactome:REACT_15518, GO:0033700=PMID:11162594, GO:0007596=Reactome:REACT_604, GO:0050728=PMID:21571275, GO:0001935=GO_REF:0000019, GO:0002576=Reactome:REACT_318, GO:0006869=GO_REF:0000038, GO:0001932=GO_REF:0000019, GO:0008211=GO_REF:0000019, GO:0005769=Reactome:REACT_160272} P02647 Apolipoprotein A-I protein 20120601 {GO:0005515=IPI, GO:0006695=IEA, GO:0043627=IEA, GO:0007603=TAS, GO:0019915=IEA, GO:0060192=IEA, GO:0030300=IEA, GO:0018206=IDA, GO:0010903=IDA, GO:0030301=IDA, GO:0005615=ISS, GO:0042802=IPI, GO:0034361=IDA, GO:0034364=IDA, GO:0034115=IDA, GO:0055102=IEA, GO:0044255=TAS, GO:0006656=IDA, GO:0042632=IDA, GO:0033344=IDA, GO:0060761=IDA, GO:0051345=IDA, GO:0043691=IMP, GO:0034366=IDA, GO:0030168=TAS, GO:0051347=IEA, GO:0005548=IEA, GO:0010804=IDA, GO:0070508=IMP, GO:0043534=IEA, GO:0007186=IDA, GO:0034375=IC, GO:0042157=TAS, GO:0055091=IDA, GO:0005788=TAS, GO:0019899=IPI, GO:0034774=TAS, GO:0042158=IEA, GO:0008035=IEA, GO:0006629=TAS, GO:0030325=IEA, GO:0005886=TAS, GO:0031100=IEA, GO:0017127=IDA, GO:0010873=IDA, GO:0070328=IDA, GO:0050713=IDA, GO:0030139=IDA, GO:0005634=IEA, GO:0044281=TAS, GO:0060228=IDA, GO:0005829=TAS, GO:0008289=IEA, GO:0002740=IDA, GO:0034384=IC, GO:0005543=IDA, GO:0001540=IDA, GO:0034191=IPI, GO:0015485=IDA, GO:0014012=IEA, GO:0034190=IPI, GO:0034380=IDA, GO:0018158=IDA, GO:0070653=IPI, GO:0008203=IMP, GO:0032489=IDA, GO:0007584=IEA, GO:0042493=IEA, GO:0050821=IDA, GO:0005576=TAS, GO:0031410=IDA, GO:0001523=TAS, GO:0055085=TAS, GO:0033700=IDA, GO:0007596=TAS, GO:0050728=IDA, GO:0001935=IEA, GO:0002576=TAS, GO:0006869=IEA, GO:0001932=IEA, GO:0008211=IEA, GO:0005769=TAS} G-protein coupled receptor signaling pathway, adrenal gland development, blood coagulation, blood vessel endothelial cell migration, cellular lipid metabolic process, cholesterol biosynthetic process, cholesterol efflux, cholesterol homeostasis, cholesterol import, cholesterol metabolic process, cholesterol transport, endothelial cell proliferation, glucocorticoid metabolic process, high-density lipoprotein particle assembly, high-density lipoprotein particle clearance, high-density lipoprotein particle remodeling, lipid metabolic process, lipid storage, lipid transport, lipoprotein biosynthetic process, lipoprotein metabolic process, negative regulation of cytokine secretion involved in immune response, negative regulation of heterotypic cell-cell adhesion, negative regulation of inflammatory response, negative regulation of interleukin-1 beta secretion, negative regulation of lipase activity, negative regulation of response to cytokine stimulus, negative regulation of tumor necrosis factor-mediated signaling pathway, negative regulation of very-low-density lipoprotein particle remodeling, organ regeneration, peptidyl-methionine modification, peripheral nervous system axon regeneration, phosphatidylcholine biosynthetic process, phospholipid efflux, phospholipid homeostasis, phototransduction, visible light, platelet activation, platelet degranulation, positive regulation of cholesterol esterification, positive regulation of hydrolase activity, positive regulation of transferase activity, protein oxidation, protein stabilization, regulation of Cdc42 protein signal transduction, regulation of intestinal cholesterol absorption, regulation of protein phosphorylation, response to drug, response to estrogen stimulus, response to nutrient, retinoid metabolic process, reverse cholesterol transport, small molecule metabolic process, transmembrane transport, triglyceride homeostasis cytoplasmic vesicle, cytosol, early endosome, endocytic vesicle, endoplasmic reticulum lumen, extracellular region, extracellular space, high-density lipoprotein particle, nucleus, plasma membrane, secretory granule lumen, spherical high-density lipoprotein particle, very-low-density lipoprotein particle apolipoprotein A-I receptor binding, apolipoprotein receptor binding, beta-amyloid binding, cholesterol binding, cholesterol transporter activity, enzyme binding, high-density lipoprotein particle binding, high-density lipoprotein particle receptor binding, identical protein binding, lipase inhibitor activity, lipid binding, phosphatidylcholine-sterol O-acyltransferase activator activity, phospholipid binding, phospholipid transporter activity, protein binding Human APOA1BP BHF-UCL UniProtKB {GO:0005515=PMID:11991719, GO:0005739=GO_REF:0000039, GO:0008150=GO_REF:0000015, GO:0000166=GO_REF:0000037, GO:0051289=GO_REF:0000019, GO:0005576=PMID:11991719, GO:0005615=PMID:22261194, GO:0044297=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0052856=GO_REF:0000020, GO:0046872=GO_REF:0000037} Q8NCW5 NAD(P)H-hydrate epimerase protein 20120228 {GO:0005515=IPI, GO:0005739=IEA, GO:0008150=ND, GO:0000166=IEA, GO:0051289=IEA, GO:0005576=IDA, GO:0005615=ISS, GO:0044297=IEA, GO:0042803=IEA, GO:0052856=IEA, GO:0046872=IEA} biological_process, protein homotetramerization cell body, extracellular region, extracellular space, mitochondrion NADHX epimerase activity, metal ion binding, nucleotide binding, protein binding, protein homodimerization activity Human UniProtKB:Q0PIT9 APOA2 BHF-UCL UniProtKB {GO:0005515=PMID:17786215, GO:0043627=GO_REF:0000019, GO:0007603=Reactome:REACT_160125, GO:0060192=PMID:14967812, GO:0018206=PMID:12576517, GO:0030300=GO_REF:0000019, GO:0010903=PMID:14967812, GO:0042803=PMID:17264082, GO:0034361=PMID:8245722, GO:0034364=PMID:17264082, GO:0006457=PMID:14967812, GO:0055102=PMID:14967812, GO:0044255=Reactome:REACT_22279, GO:0006656=PMID:14967812, GO:0042632=PMID:14967812, GO:0033344=PMID:11162594, GO:0002526=GO_REF:0000019, GO:0046982=PMID:8245722, GO:0043691=PMID:14967812, GO:0045416=PMID:11591715, GO:0034366=PMID:16682745, GO:0051384=GO_REF:0000019, GO:0034370=PMID:14967812, GO:0034374=PMID:8106353, GO:0034375=PMID:14967812, GO:0042157=Reactome:REACT_6841, GO:0005788=Reactome:REACT_6915, GO:0006641=PMID:11551871, GO:0005319=PMID:1606170, GO:0006629=Reactome:REACT_602, GO:0008035=GO_REF:0000019, GO:0032375=PMID:8636092, GO:0050996=PMID:8640403, GO:0050995=PMID:14967812, GO:0060695=PMID:8106353, GO:0031100=GO_REF:0000019, GO:0017127=PMID:9651324, GO:0042627=PMID:8245722, GO:0010873=PMID:14967812, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_160215, GO:0002740=PMID:12458630, GO:0060228=PMID:14967812, GO:0008289=PMID:14967812, GO:0031647=PMID:14967812, GO:0005543=PMID:218942, GO:0034384=PMID:10764676, GO:0015485=PMID:218942, GO:0018158=PMID:12576517, GO:0034380=PMID:218942, GO:0034190=PMID:11162594, GO:0070653=PMID:10764676, GO:0060621=PMID:10764676, GO:0008203=GO_REF:0000019, GO:0046340=PMID:14967812, GO:0042493=GO_REF:0000019, GO:0031210=PMID:17264082, GO:0005576=Reactome:REACT_160272, GO:0001523=Reactome:REACT_24968, GO:0009749=PMID:14988251, GO:0033700=PMID:11162594, GO:0019048=GO_REF:0000037, GO:0009395=PMID:14967812, GO:0005769=Reactome:REACT_160272} P02652 Apolipoprotein A-II protein 20080402 {GO:0005515=IPI, GO:0043627=IEA, GO:0007603=TAS, GO:0060192=IDA, GO:0018206=IDA, GO:0030300=IEA, GO:0010903=IDA, GO:0042803=IDA, GO:0034361=IDA, GO:0034364=IDA, GO:0006457=IDA, GO:0055102=IDA, GO:0044255=TAS, GO:0006656=IDA, GO:0042632=IDA, GO:0033344=IDA, GO:0002526=IEA, GO:0046982=IPI, GO:0043691=IDA, GO:0045416=IDA, GO:0034366=IDA, GO:0051384=IEA, GO:0034370=IDA, GO:0034374=IDA, GO:0034375=IDA, GO:0042157=TAS, GO:0005788=TAS, GO:0006641=TAS, GO:0005319=IDA, GO:0006629=TAS, GO:0008035=IEA, GO:0032375=IMP, GO:0050996=IDA, GO:0050995=IDA, GO:0060695=IDA, GO:0031100=IEA, GO:0017127=IDA, GO:0042627=IDA, GO:0010873=IDA, GO:0044281=TAS, GO:0005829=TAS, GO:0002740=IDA, GO:0060228=IDA, GO:0008289=IDA, GO:0031647=IDA, GO:0005543=IDA, GO:0034384=IDA, GO:0015485=IDA, GO:0018158=IDA, GO:0034380=IDA, GO:0034190=IPI, GO:0070653=IPI, GO:0060621=IDA, GO:0008203=IEA, GO:0046340=IDA, GO:0042493=IEA, GO:0031210=IDA, GO:0005576=TAS, GO:0001523=TAS, GO:0009749=IDA, GO:0033700=IDA, GO:0019048=IEA, GO:0009395=IDA, GO:0005769=TAS} acute inflammatory response, cellular lipid metabolic process, cholesterol efflux, cholesterol homeostasis, cholesterol metabolic process, diacylglycerol catabolic process, high-density lipoprotein particle assembly, high-density lipoprotein particle clearance, high-density lipoprotein particle remodeling, lipid metabolic process, lipoprotein metabolic process, low-density lipoprotein particle remodeling, negative regulation of cholesterol import, negative regulation of cholesterol transport, negative regulation of cholesterol transporter activity, negative regulation of cytokine secretion involved in immune response, negative regulation of lipase activity, negative regulation of lipid catabolic process, negative regulation of very-low-density lipoprotein particle remodeling, organ regeneration, peptidyl-methionine modification, phosphatidylcholine biosynthetic process, phospholipid catabolic process, phospholipid efflux, phototransduction, visible light, positive regulation of cholesterol esterification, positive regulation of interleukin-8 biosynthetic process, positive regulation of lipid catabolic process, protein folding, protein oxidation, regulation of intestinal cholesterol absorption, regulation of protein stability, response to drug, response to estrogen stimulus, response to glucocorticoid stimulus, response to glucose stimulus, retinoid metabolic process, reverse cholesterol transport, small molecule metabolic process, triglyceride metabolic process, triglyceride-rich lipoprotein particle remodeling, virus-host interaction chylomicron, cytosol, early endosome, endoplasmic reticulum lumen, extracellular region, high-density lipoprotein particle, spherical high-density lipoprotein particle, very-low-density lipoprotein particle apolipoprotein receptor binding, cholesterol binding, cholesterol transporter activity, high-density lipoprotein particle binding, high-density lipoprotein particle receptor binding, lipase inhibitor activity, lipid binding, lipid transporter activity, phosphatidylcholine binding, phosphatidylcholine-sterol O-acyltransferase activator activity, phospholipid binding, protein binding, protein heterodimerization activity, protein homodimerization activity Human APOA4 BHF-UCL UniProtKB {GO:0035634=GO_REF:0000019, GO:0043499=PMID:1935934, GO:0007603=Reactome:REACT_160125, GO:0006982=PMID:16945374, GO:0010898=PMID:2307668, GO:0030300=GO_REF:0000019, GO:0005615=PMID:1935934, GO:0042803=PMID:1935934, GO:0034361=PMID:3095477, GO:0034364=PMID:3095477, GO:0019430=PMID:16945374, GO:0034445=PMID:16945374, GO:0042744=PMID:16945374, GO:0042632=PMID:1935934, GO:0033344=PMID:11162594, GO:0016209=PMID:16945374, GO:0032374=PMID:11940599, GO:0009986=PMID:1935934, GO:0005507=PMID:16945374, GO:0043691=PMID:3095477, GO:0065005=PMID:16159879, GO:0002227=PMID:15254593, GO:0034372=PMID:2307668, GO:0034371=PMID:2307668, GO:0034375=PMID:1935934, GO:0042157=Reactome:REACT_6841, GO:0005788=Reactome:REACT_6915, GO:0005319=PMID:3080432, GO:0051006=PMID:2307668, GO:0006629=Reactome:REACT_602, GO:0017127=PMID:1935934, GO:0044240=PMID:3095477, GO:0010873=PMID:1935934, GO:0042627=PMID:3095477, GO:0044281=Reactome:REACT_111217, GO:0034378=PMID:16159879, GO:0005829=Reactome:REACT_160215, GO:0008289=PMID:16159879, GO:0060228=PMID:1935934, GO:0007159=PMID:15254593, GO:0008203=PMID:1935934, GO:0045723=PMID:2307668, GO:0055088=PMID:3095477, GO:0031210=PMID:1935934, GO:0005576=Reactome:REACT_160272, GO:0001523=Reactome:REACT_24968, GO:0033700=PMID:11162594, GO:0006869=PMID:1935934, GO:0046470=PMID:1935934, GO:0005769=Reactome:REACT_160272} P06727 Apolipoprotein A-IV protein 20100511 {GO:0035634=IEA, GO:0043499=IDA, GO:0007603=TAS, GO:0006982=IDA, GO:0010898=IDA, GO:0030300=IEA, GO:0005615=IDA, GO:0042803=IDA, GO:0034361=IDA, GO:0034364=IDA, GO:0019430=IDA, GO:0034445=IDA, GO:0042744=IDA, GO:0042632=IDA, GO:0033344=IDA, GO:0016209=IDA, GO:0032374=IDA, GO:0009986=IDA, GO:0005507=IDA, GO:0043691=IDA, GO:0065005=IMP, GO:0002227=IDA, GO:0034372=IDA, GO:0034371=IC, GO:0034375=IC, GO:0042157=TAS, GO:0005788=TAS, GO:0005319=TAS, GO:0051006=IDA, GO:0006629=TAS, GO:0017127=IDA, GO:0044240=IDA, GO:0010873=IDA, GO:0042627=IDA, GO:0044281=TAS, GO:0034378=TAS, GO:0005829=TAS, GO:0008289=IMP, GO:0060228=IDA, GO:0007159=IDA, GO:0008203=IDA, GO:0045723=IDA, GO:0055088=IDA, GO:0031210=IDA, GO:0005576=TAS, GO:0001523=TAS, GO:0033700=IDA, GO:0006869=IDA, GO:0046470=IDA, GO:0005769=TAS} cholesterol efflux, cholesterol homeostasis, cholesterol metabolic process, chylomicron assembly, chylomicron remodeling, high-density lipoprotein particle remodeling, hydrogen peroxide catabolic process, innate immune response in mucosa, leukocyte cell-cell adhesion, lipid homeostasis, lipid metabolic process, lipid transport, lipoprotein metabolic process, multicellular organismal lipid catabolic process, negative regulation of plasma lipoprotein particle oxidation, phosphatidylcholine metabolic process, phospholipid efflux, phototransduction, visible light, positive regulation of cholesterol esterification, positive regulation of fatty acid biosynthetic process, positive regulation of lipoprotein lipase activity, positive regulation of triglyceride catabolic process, protein-lipid complex assembly, regulation of cholesterol transport, regulation of intestinal cholesterol absorption, removal of superoxide radicals, response to lipid hydroperoxide, response to stilbenoid, retinoid metabolic process, reverse cholesterol transport, small molecule metabolic process, very-low-density lipoprotein particle remodeling cell surface, chylomicron, cytosol, early endosome, endoplasmic reticulum lumen, extracellular region, extracellular space, high-density lipoprotein particle, very-low-density lipoprotein particle antioxidant activity, cholesterol transporter activity, copper ion binding, eukaryotic cell surface binding, lipid binding, lipid transporter activity, phosphatidylcholine binding, phosphatidylcholine-sterol O-acyltransferase activator activity, protein homodimerization activity colocalizes_with Human APOA5 BHF-UCL UniProtKB {GO:0005515=PMID:17997385, GO:0050996=PMID:16806135, GO:0031100=GO_REF:0000019, GO:0042627=PMID:15528295, GO:0070328=PMID:19121291, GO:0010898=PMID:18635818, GO:0010902=PMID:18635818, GO:0044281=Reactome:REACT_111217, GO:0042246=PMID:11577099, GO:0070325=PMID:18635818, GO:0005615=PMID:19121291, GO:0060229=PMID:15178420, GO:0008289=PMID:12810715, GO:0034361=PMID:15528295, GO:0005543=PMID:12810715, GO:0034364=PMID:15528295, GO:0034362=PMID:15528295, GO:0019433=PMID:15178420, GO:0009725=GO_REF:0000019, GO:0008201=PMID:17326667, GO:0044255=Reactome:REACT_22279, GO:0042632=PMID:19121291, GO:0045723=PMID:18635818, GO:0031210=PMID:16806135, GO:0005576=Reactome:REACT_115631, GO:0060230=PMID:18635818, GO:0034370=GO_REF:0000019, GO:0006869=PMID:15178420, GO:0048260=PMID:18635818, GO:0042157=GO_REF:0000002, GO:0006641=PMID:11588264, GO:0055090=PMID:11588264, GO:0035473=PMID:15178420, GO:0008047=PMID:16806135, GO:0019899=PMID:15178420, GO:0050750=PMID:17326667, GO:0051006=PMID:16806135} Q6Q788 Apolipoprotein A-V protein 20121031 {GO:0005515=IPI, GO:0050996=IDA, GO:0031100=IEA, GO:0042627=IDA, GO:0070328=IDA, GO:0010898=IDA, GO:0010902=IDA, GO:0044281=TAS, GO:0042246=IEP, GO:0070325=IPI, GO:0005615=IDA, GO:0060229=IMP, GO:0008289=IDA, GO:0034361=IDA, GO:0005543=IDA, GO:0034364=IDA, GO:0034362=IDA, GO:0019433=IMP, GO:0009725=IEA, GO:0008201=IDA, GO:0044255=TAS, GO:0042632=IDA, GO:0045723=IDA, GO:0031210=IDA, GO:0005576=TAS, GO:0060230=IDA, GO:0034370=IEA, GO:0006869=IDA, GO:0048260=TAS, GO:0042157=IEA, GO:0006641=IDA, GO:0055090=IDA, GO:0035473=IPI, GO:0008047=IDA, GO:0019899=IDA, GO:0050750=IPI, GO:0051006=IDA} acylglycerol homeostasis, cellular lipid metabolic process, cholesterol homeostasis, lipid transport, lipoprotein metabolic process, organ regeneration, positive regulation of fatty acid biosynthetic process, positive regulation of lipid catabolic process, positive regulation of lipoprotein lipase activity, positive regulation of receptor-mediated endocytosis, positive regulation of triglyceride catabolic process, positive regulation of very-low-density lipoprotein particle remodeling, response to hormone stimulus, small molecule metabolic process, tissue regeneration, triglyceride catabolic process, triglyceride homeostasis, triglyceride metabolic process, triglyceride-rich lipoprotein particle remodeling chylomicron, extracellular region, extracellular space, high-density lipoprotein particle, low-density lipoprotein particle, very-low-density lipoprotein particle enzyme activator activity, enzyme binding, heparin binding, lipase activator activity, lipase binding, lipid binding, lipoprotein lipase activator activity, lipoprotein particle receptor binding, low-density lipoprotein particle receptor binding, phosphatidylcholine binding, phospholipid binding, protein binding Human UniProtKB:P06858 APOB BHF-UCL UniProtKB {GO:0005515=PMID:22580899, GO:0007603=Reactome:REACT_160125, GO:0048844=GO_REF:0000019, GO:0030301=PMID:2563166, GO:0007283=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0050900=Reactome:REACT_12051, GO:0005615=PMID:22261194, GO:0034359=PMID:4363408, GO:0043231=PMID:7853698, GO:0034361=PMID:15308631, GO:0034360=PMID:6099394, GO:0042953=GO_REF:0000019, GO:0009743=GO_REF:0000019, GO:0034363=PMID:1917954, GO:0034362=PMID:4363408, GO:0071356=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0019433=GO_REF:0000019, GO:0042632=PMID:2563166, GO:0033344=GO_REF:0000019, GO:0046982=PMID:8245722, GO:0010744=PMID:17244792, GO:0001701=GO_REF:0000019, GO:0006898=Reactome:REACT_6934, GO:0009566=GO_REF:0000019, GO:0034374=PMID:15797858, GO:0005789=Reactome:REACT_6908, GO:0042157=Reactome:REACT_6841, GO:0005788=Reactome:REACT_6915, GO:0019899=PMID:9685400, GO:0006642=GO_REF:0000019, GO:0005319=GO_REF:0000002, GO:0042159=GO_REF:0000019, GO:0010008=Reactome:REACT_6901, GO:0042158=GO_REF:0000019, GO:0006629=Reactome:REACT_602, GO:0005886=Reactome:REACT_6940, GO:0017127=PMID:15797858, GO:0045540=GO_REF:0000019, GO:0042627=PMID:8245722, GO:0044281=Reactome:REACT_111217, GO:0034379=PMID:15308631, GO:0005829=Reactome:REACT_160215, GO:0005737=PMID:22580899, GO:0005543=PMID:7126555, GO:0034383=PMID:2563166, GO:0071379=GO_REF:0000019, GO:0008201=PMID:16233946, GO:0008203=PMID:2563166, GO:0010269=GO_REF:0000019, GO:0005576=Reactome:REACT_160272, GO:0010884=PMID:18322245, GO:0031983=GO_REF:0000019, GO:0030317=GO_REF:0000019, GO:0009615=PMID:16548883, GO:0010886=PMID:19114110, GO:0001523=Reactome:REACT_24968, GO:0007399=GO_REF:0000019, GO:0031904=Reactome:REACT_6775, GO:0007596=Reactome:REACT_604, GO:0030669=Reactome:REACT_6924, GO:0005769=Reactome:REACT_160272, GO:0050750=PMID:15797858} P04114 Apolipoprotein B-100 protein 20080423 {GO:0005515=IPI, GO:0007603=TAS, GO:0048844=IEA, GO:0030301=IMP, GO:0007283=IEA, GO:0009791=IEA, GO:0050900=TAS, GO:0005615=ISS, GO:0034359=IDA, GO:0043231=TAS, GO:0034361=IDA, GO:0034360=TAS, GO:0042953=IEA, GO:0009743=IEA, GO:0034363=IDA, GO:0034362=IDA, GO:0071356=IEA, GO:0032496=IEA, GO:0019433=IEA, GO:0042632=IMP, GO:0033344=IEA, GO:0046982=IPI, GO:0010744=IDA, GO:0001701=IEA, GO:0006898=TAS, GO:0009566=IEA, GO:0034374=IMP, GO:0005789=TAS, GO:0042157=TAS, GO:0005788=TAS, GO:0019899=IPI, GO:0006642=IEA, GO:0005319=IEA, GO:0042159=IEA, GO:0010008=TAS, GO:0042158=IEA, GO:0006629=TAS, GO:0005886=TAS, GO:0017127=IMP, GO:0045540=IEA, GO:0042627=IDA, GO:0044281=TAS, GO:0034379=IC, GO:0005829=TAS, GO:0005737=IDA, GO:0005543=IDA, GO:0034383=IMP, GO:0071379=IEA, GO:0008201=IDA, GO:0008203=IMP, GO:0010269=IEA, GO:0005576=TAS, GO:0010884=IDA, GO:0031983=IEA, GO:0030317=IEA, GO:0009615=IEP, GO:0010886=IDA, GO:0001523=TAS, GO:0007399=IEA, GO:0031904=TAS, GO:0007596=TAS, GO:0030669=TAS, GO:0005769=TAS, GO:0050750=IMP} artery morphogenesis, blood coagulation, cellular response to prostaglandin stimulus, cellular response to tumor necrosis factor, cholesterol efflux, cholesterol homeostasis, cholesterol metabolic process, cholesterol transport, fertilization, in utero embryonic development, leukocyte migration, lipid metabolic process, lipoprotein biosynthetic process, lipoprotein catabolic process, lipoprotein metabolic process, lipoprotein transport, low-density lipoprotein particle clearance, low-density lipoprotein particle remodeling, nervous system development, phototransduction, visible light, positive regulation of cholesterol storage, positive regulation of lipid storage, positive regulation of macrophage derived foam cell differentiation, post-embryonic development, receptor-mediated endocytosis, regulation of cholesterol biosynthetic process, response to carbohydrate stimulus, response to lipopolysaccharide, response to selenium ion, response to virus, retinoid metabolic process, small molecule metabolic process, sperm motility, spermatogenesis, triglyceride catabolic process, triglyceride mobilization, very-low-density lipoprotein particle assembly chylomicron, chylomicron remnant, clathrin-coated endocytic vesicle membrane, cytoplasm, cytosol, early endosome, endoplasmic reticulum lumen, endoplasmic reticulum membrane, endosome lumen, endosome membrane, extracellular region, extracellular space, intermediate-density lipoprotein particle, intracellular membrane-bounded organelle, low-density lipoprotein particle, mature chylomicron, plasma membrane, very-low-density lipoprotein particle, vesicle lumen cholesterol transporter activity, enzyme binding, heparin binding, lipid transporter activity, low-density lipoprotein particle receptor binding, phospholipid binding, protein binding, protein heterodimerization activity Human APOBEC1 GOC UniProtKB {GO:0005515=PMID:10669759, GO:0006629=PMID:8078915, GO:0010467=Reactome:REACT_71, GO:0009972=PMID:7736571, GO:0045471=GO_REF:0000019, GO:0003723=PMID:7736571, GO:0010043=GO_REF:0000019, GO:0005737=PMID:22580899, GO:0042953=GO_REF:0000019, GO:0051607=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0080111=GO_REF:0000024, GO:0017091=GO_REF:0000019, GO:0004126=PMID:7736571, GO:0048255=GO_REF:0000019, GO:0010332=GO_REF:0000019, GO:0006397=GO_REF:0000037, GO:0006396=PMID:7736571, GO:0032869=GO_REF:0000019, GO:0016556=Reactome:REACT_1757, GO:0042493=GO_REF:0000019, GO:0016554=Reactome:REACT_167, GO:0006970=GO_REF:0000019, GO:0090310=GO_REF:0000024, GO:0051592=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_869, GO:0042158=GO_REF:0000019} P41238 C->U-editing enzyme APOBEC-1 protein 20130413 {GO:0005515=IPI, GO:0006629=TAS, GO:0010467=TAS, GO:0009972=TAS, GO:0045471=IEA, GO:0003723=TAS, GO:0010043=IEA, GO:0005737=IDA, GO:0042953=IEA, GO:0051607=IEA, GO:0042127=IEA, GO:0080111=ISS, GO:0017091=IEA, GO:0004126=TAS, GO:0048255=IEA, GO:0010332=IEA, GO:0006397=IEA, GO:0006396=TAS, GO:0032869=IEA, GO:0016556=TAS, GO:0042493=IEA, GO:0016554=TAS, GO:0006970=IEA, GO:0090310=ISS, GO:0051592=IEA, GO:0008270=IEA, GO:0005654=TAS, GO:0042158=IEA} DNA demethylation, RNA processing, cellular response to insulin stimulus, cytidine deamination, cytidine to uridine editing, defense response to virus, gene expression, lipid metabolic process, lipoprotein biosynthetic process, lipoprotein transport, mRNA modification, mRNA processing, mRNA stabilization, negative regulation of methylation-dependent chromatin silencing, regulation of cell proliferation, response to calcium ion, response to drug, response to ethanol, response to gamma radiation, response to osmotic stress, response to zinc ion cytoplasm, nucleoplasm AU-rich element binding, RNA binding, cytidine deaminase activity, protein binding, zinc ion binding Human APOBEC2 GOC UniProtKB {GO:0006397=GO_REF:0000037, GO:0009972=PMID:10403781, GO:0016556=GO_REF:0000019, GO:0003723=PMID:10403781, GO:0080111=PMID:21496894, GO:0004126=PMID:10403781, GO:0008270=GO_REF:0000002} Q9Y235 Probable C->U-editing enzyme APOBEC-2 protein 20130413 {GO:0006397=IEA, GO:0009972=TAS, GO:0016556=IEA, GO:0003723=TAS, GO:0080111=IDA, GO:0004126=TAS, GO:0008270=IEA} DNA demethylation, cytidine deamination, mRNA modification, mRNA processing RNA binding, cytidine deaminase activity, zinc ion binding Human APOBEC3A GOC UniProtKB {GO:0005515=PMID:22915799, GO:0009972=PMID:21123384, GO:0047844=PMID:22457529, GO:0005634=PMID:21835787, GO:0010529=PMID:20062055, GO:0071466=PMID:20062055, GO:0044356=PMID:20062055, GO:0051607=PMID:22457529, GO:0005737=PMID:21835787, GO:0045087=PMID:21123384, GO:0080111=PMID:21496894, GO:0004126=PMID:20062055, GO:0008270=GO_REF:0000002, GO:0045071=PMID:16527742, GO:0070383=PMID:21123384} P31941 DNA dC->dU-editing enzyme APOBEC-3A protein 20130413 {GO:0005515=IPI, GO:0009972=IDA, GO:0047844=IMP, GO:0005634=IDA, GO:0010529=IDA, GO:0071466=IDA, GO:0044356=IDA, GO:0051607=IDA, GO:0005737=IDA, GO:0045087=IDA, GO:0080111=IDA, GO:0004126=IMP, GO:0008270=IEA, GO:0045071=IDA, GO:0070383=IDA} DNA cytosine deamination, DNA demethylation, cellular response to xenobiotic stimulus, clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine, cytidine deamination, defense response to virus, innate immune response, negative regulation of transposition, negative regulation of viral genome replication cytoplasm, nucleus cytidine deaminase activity, deoxycytidine deaminase activity, protein binding, zinc ion binding Human APOBEC3B UniProtKB UniProtKB {GO:0016814=GO_REF:0000002, GO:0051607=PMID:22915799, GO:0047844=PMID:22457529, GO:0003723=GO_REF:0000037, GO:0045087=GO_REF:0000037, GO:0005634=PMID:21835787, GO:0008270=GO_REF:0000002, GO:0010529=PMID:20062055} Q9UH17 DNA dC->dU-editing enzyme APOBEC-3B protein 20130130 {GO:0016814=IEA, GO:0051607=IDA, GO:0047844=IMP, GO:0003723=IEA, GO:0045087=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0010529=IDA} defense response to virus, innate immune response, negative regulation of transposition nucleus RNA binding, deoxycytidine deaminase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines, zinc ion binding Human APOBEC3C UniProtKB UniProtKB {GO:0005515=PMID:22915799, GO:0016814=GO_REF:0000002, GO:0005737=PMID:21835787, GO:0051607=GO_REF:0000037, GO:0009972=PMID:21632763, GO:0045087=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0080111=PMID:21496894, GO:0005634=PMID:21835787, GO:0008270=GO_REF:0000002, GO:0010529=PMID:20062055, GO:0045071=PMID:21632763} Q9NRW3 DNA dC->dU-editing enzyme APOBEC-3C protein 20130130 {GO:0005515=IPI, GO:0016814=IEA, GO:0005737=IDA, GO:0051607=IEA, GO:0009972=IDA, GO:0045087=IEA, GO:0019048=IEA, GO:0080111=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0010529=IDA, GO:0045071=IDA} DNA demethylation, cytidine deamination, defense response to virus, innate immune response, negative regulation of transposition, negative regulation of viral genome replication, virus-host interaction cytoplasm, nucleus hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines, protein binding, zinc ion binding Human APOBEC3D UniProtKB UniProtKB {GO:0016814=GO_REF:0000002, GO:0005737=PMID:21835787, GO:0051607=PMID:21835787, GO:0000932=PMID:22915799, GO:0045087=GO_REF:0000037, GO:0045869=PMID:21835787, GO:0008270=GO_REF:0000002, GO:0010529=PMID:20062055, GO:0070383=PMID:21835787} Q96AK3 DNA dC->dU-editing enzyme APOBEC-3D protein 20130130 {GO:0016814=IEA, GO:0005737=IDA, GO:0051607=IDA, GO:0000932=IDA, GO:0045087=IEA, GO:0045869=IDA, GO:0008270=IEA, GO:0010529=IDA, GO:0070383=IDA} DNA cytosine deamination, defense response to virus, innate immune response, negative regulation of retroviral genome replication, negative regulation of transposition cytoplasm, cytoplasmic mRNA processing body hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines, zinc ion binding Human APOBEC3F GOC UniProtKB {GO:0030895=PMID:17121840, GO:0005515=PMID:22915799, GO:0009972=PMID:17121840, GO:0016553=PMID:17121840, GO:0003723=PMID:11863358, GO:0045869=PMID:17121840, GO:0048525=PMID:17121840, GO:0010529=PMID:20062055, GO:0005737=PMID:21835787, GO:0051607=PMID:22915799, GO:0000932=PMID:22915799, GO:0030529=PMID:16699599, GO:0002230=PMID:17121840, GO:0045087=PMID:17121840, GO:0080111=PMID:21496894, GO:0004126=PMID:17121840, GO:0008270=PMID:11863358, GO:0045071=PMID:17121840, GO:0070383=PMID:21835787} Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F protein 20130413 {GO:0030895=TAS, GO:0005515=IPI, GO:0009972=IDA, GO:0016553=IDA, GO:0003723=IDA, GO:0045869=IDA, GO:0048525=IDA, GO:0010529=IDA, GO:0005737=IDA, GO:0051607=IDA, GO:0000932=IDA, GO:0030529=IDA, GO:0002230=IDA, GO:0045087=IDA, GO:0080111=IDA, GO:0004126=IDA, GO:0008270=IDA, GO:0045071=IDA, GO:0070383=IDA} DNA cytosine deamination, DNA demethylation, base conversion or substitution editing, cytidine deamination, defense response to virus, innate immune response, negative regulation of retroviral genome replication, negative regulation of transposition, negative regulation of viral genome replication, negative regulation of viral reproduction, positive regulation of defense response to virus by host apolipoprotein B mRNA editing enzyme complex, cytoplasm, cytoplasmic mRNA processing body, ribonucleoprotein complex RNA binding, cytidine deaminase activity, protein binding, zinc ion binding Human APOBEC3G HPA UniProtKB {GO:0030895=PMID:17121840, GO:0005515=PMID:22915799, GO:0009972=PMID:16378963, GO:0047844=PMID:12808465, GO:0016553=PMID:17121840, GO:0003723=PMID:11863358, GO:0045869=PMID:17121840, GO:0048525=PMID:17121840, GO:0010529=PMID:16527742, GO:0042803=PMID:11863358, GO:0005829=Reactome:REACT_9471, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0051607=PMID:22915799, GO:0000932=PMID:22915799, GO:0045087=PMID:17121840, GO:0019048=GO_REF:0000037, GO:0030529=PMID:16699599, GO:0002230=PMID:17121840, GO:0016032=Reactome:REACT_6185, GO:0004126=PMID:17121840, GO:0008270=PMID:11863358, GO:0045071=PMID:17121840, GO:0070383=PMID:21835787} Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G protein 20101115 {GO:0030895=TAS, GO:0005515=IPI, GO:0009972=IDA, GO:0047844=IDA, GO:0016553=TAS, GO:0003723=IDA, GO:0045869=IDA, GO:0048525=IDA, GO:0010529=IDA, GO:0042803=NAS, GO:0005829=TAS, GO:0005739=IDA, GO:0005737=IDA, GO:0051607=IDA, GO:0000932=IDA, GO:0045087=IDA, GO:0019048=IEA, GO:0030529=IDA, GO:0002230=IDA, GO:0016032=TAS, GO:0004126=TAS, GO:0008270=IDA, GO:0045071=IDA, GO:0070383=IDA} DNA cytosine deamination, base conversion or substitution editing, cytidine deamination, defense response to virus, innate immune response, negative regulation of retroviral genome replication, negative regulation of transposition, negative regulation of viral genome replication, negative regulation of viral reproduction, positive regulation of defense response to virus by host, viral reproduction, virus-host interaction apolipoprotein B mRNA editing enzyme complex, cytoplasm, cytoplasmic mRNA processing body, cytosol, mitochondrion, ribonucleoprotein complex RNA binding, cytidine deaminase activity, deoxycytidine deaminase activity, protein binding, protein homodimerization activity, zinc ion binding Human APOBEC4 UniProtKB UniProtKB {GO:0006397=GO_REF:0000037, GO:0016814=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q8WW27 Putative C->U-editing enzyme APOBEC-4 protein 20130413 {GO:0006397=IEA, GO:0016814=IEA, GO:0008270=IEA} mRNA processing hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines, zinc ion binding Human UniProtKB-KW:KW-0507 APOC1 BHF-UCL UniProtKB {GO:0006629=PMID:2897845, GO:0032375=PMID:10978346, GO:0050995=PMID:15576844, GO:0005783=GO_REF:0000054, GO:0010900=PMID:2302419, GO:0010873=PMID:18992221, GO:0042627=PMID:18992221, GO:0034379=PMID:18992221, GO:0060228=PMID:18992221, GO:0034361=PMID:15576844, GO:0034364=PMID:15576844, GO:0034382=PMID:4020294, GO:0055102=PMID:15576844, GO:0034447=PMID:15576844, GO:0033344=PMID:11162594, GO:0004859=PMID:2302419, GO:0005504=PMID:17339654, GO:0032374=PMID:15576844, GO:0045717=PMID:15576844, GO:0031210=PMID:2302419, GO:0005576=GO_REF:0000002, GO:0034369=PMID:10978346, GO:0051005=PMID:15576844, GO:0010916=PMID:1917954, GO:0033700=PMID:11162594, GO:0048261=PMID:1917954, GO:0034375=PMID:18992221, GO:0042157=GO_REF:0000002, GO:0045833=PMID:182536} P02654 Apolipoprotein C-I protein 20080402 {GO:0006629=TAS, GO:0032375=IDA, GO:0050995=IDA, GO:0005783=IDA, GO:0010900=IDA, GO:0010873=TAS, GO:0042627=TAS, GO:0034379=TAS, GO:0060228=TAS, GO:0034361=IDA, GO:0034364=IDA, GO:0034382=IDA, GO:0055102=IDA, GO:0034447=IGI, GO:0033344=IDA, GO:0004859=IDA, GO:0005504=IDA, GO:0032374=IC, GO:0045717=IDA, GO:0031210=TAS, GO:0005576=IEA, GO:0034369=IDA, GO:0051005=IDA, GO:0010916=IDA, GO:0033700=IDA, GO:0048261=IDA, GO:0034375=TAS, GO:0042157=IEA, GO:0045833=IDA} cholesterol efflux, chylomicron remnant clearance, high-density lipoprotein particle remodeling, lipid metabolic process, lipoprotein metabolic process, negative regulation of cholesterol transport, negative regulation of fatty acid biosynthetic process, negative regulation of lipid catabolic process, negative regulation of lipid metabolic process, negative regulation of lipoprotein lipase activity, negative regulation of phosphatidylcholine catabolic process, negative regulation of receptor-mediated endocytosis, negative regulation of very-low-density lipoprotein particle clearance, phospholipid efflux, plasma lipoprotein particle remodeling, positive regulation of cholesterol esterification, regulation of cholesterol transport, very-low-density lipoprotein particle assembly, very-low-density lipoprotein particle clearance chylomicron, endoplasmic reticulum, extracellular region, high-density lipoprotein particle, very-low-density lipoprotein particle fatty acid binding, lipase inhibitor activity, phosphatidylcholine binding, phosphatidylcholine-sterol O-acyltransferase activator activity, phospholipase inhibitor activity Human APOC2 ENSEMBL UniProtKB {GO:0032375=PMID:15778093, GO:0006629=GO_REF:0000002, GO:0007603=Reactome:REACT_160125, GO:0042627=GO_REF:0000002, GO:0060697=PMID:10727238, GO:0070328=PMID:17018885, GO:0010898=PMID:10727238, GO:0010902=PMID:10727238, GO:0044281=Reactome:REACT_111217, GO:0005615=PMID:10727238, GO:0042803=PMID:8245722, GO:0008289=PMID:10727238, GO:0034361=PMID:8245722, GO:0042953=GO_REF:0000019, GO:0034384=PMID:15778093, GO:0034382=PMID:4020294, GO:0043274=PMID:10727238, GO:0034363=PMID:17336988, GO:0034362=PMID:8245722, GO:0055102=PMID:182536, GO:0042632=PMID:15778093, GO:0033344=PMID:11162594, GO:0042493=GO_REF:0000019, GO:0045723=PMID:10727238, GO:0043691=PMID:15778093, GO:0034366=PMID:16682745, GO:0010518=PMID:10727238, GO:0005576=Reactome:REACT_160272, GO:0001523=Reactome:REACT_24968, GO:0060230=PMID:10727238, GO:0034370=PMID:17018885, GO:0016042=GO_REF:0000037, GO:0010916=PMID:1917954, GO:0033700=PMID:11162594, GO:0034372=PMID:15778093, GO:0034371=PMID:10727238, GO:0016004=PMID:10727238, GO:0048261=PMID:1917954, GO:0006869=GO_REF:0000002, GO:0042157=Reactome:REACT_13621, GO:0008047=GO_REF:0000002, GO:0005769=Reactome:REACT_160272, GO:0051006=PMID:15878877, GO:0045833=PMID:182536} Q6P163 APOC2 protein protein 20130413 {GO:0032375=IMP, GO:0006629=IEA, GO:0007603=TAS, GO:0042627=IEA, GO:0060697=IDA, GO:0070328=IMP, GO:0010898=IDA, GO:0010902=IC, GO:0044281=TAS, GO:0005615=IDA, GO:0042803=IMP, GO:0008289=IDA, GO:0034361=IDA, GO:0042953=IEA, GO:0034384=IMP, GO:0034382=IDA, GO:0043274=IPI, GO:0034363=IDA, GO:0034362=IDA, GO:0055102=IDA, GO:0042632=IC, GO:0033344=IDA, GO:0042493=IEA, GO:0045723=IDA, GO:0043691=IC, GO:0034366=IDA, GO:0010518=IDA, GO:0005576=TAS, GO:0001523=TAS, GO:0060230=IDA, GO:0034370=TAS, GO:0016042=IEA, GO:0010916=IDA, GO:0033700=IDA, GO:0034372=TAS, GO:0034371=IC, GO:0016004=IDA, GO:0048261=IDA, GO:0006869=IEA, GO:0042157=TAS, GO:0008047=IEA, GO:0005769=TAS, GO:0051006=IDA, GO:0045833=IDA} cholesterol efflux, cholesterol homeostasis, chylomicron remnant clearance, chylomicron remodeling, high-density lipoprotein particle clearance, lipid catabolic process, lipid metabolic process, lipid transport, lipoprotein metabolic process, lipoprotein transport, negative regulation of cholesterol transport, negative regulation of lipid metabolic process, negative regulation of receptor-mediated endocytosis, negative regulation of very-low-density lipoprotein particle clearance, phospholipid efflux, phototransduction, visible light, positive regulation of fatty acid biosynthetic process, positive regulation of lipoprotein lipase activity, positive regulation of phospholipase activity, positive regulation of phospholipid catabolic process, positive regulation of triglyceride catabolic process, positive regulation of very-low-density lipoprotein particle remodeling, response to drug, retinoid metabolic process, reverse cholesterol transport, small molecule metabolic process, triglyceride homeostasis, triglyceride-rich lipoprotein particle remodeling, very-low-density lipoprotein particle remodeling chylomicron, early endosome, extracellular region, extracellular space, intermediate-density lipoprotein particle, low-density lipoprotein particle, spherical high-density lipoprotein particle, very-low-density lipoprotein particle enzyme activator activity, lipase inhibitor activity, lipid binding, lipoprotein lipase activator activity, phospholipase activator activity, phospholipase binding, protein homodimerization activity Human Ensembl:ENSRNOP00000024800 APOC3 BHF-UCL UniProtKB {GO:0007603=Reactome:REACT_160125, GO:0010897=PMID:3973011, GO:0010903=PMID:18635818, GO:0005615=PMID:11060345, GO:0034361=PMID:17154273, GO:0042953=GO_REF:0000019, GO:0010987=PMID:15778093, GO:0034363=PMID:17336988, GO:0019433=PMID:11060345, GO:0010989=PMID:15778093, GO:0055102=PMID:3973011, GO:0042632=PMID:18767813, GO:0033344=PMID:11162594, GO:0043691=PMID:15778093, GO:0034366=PMID:17438339, GO:0051005=PMID:11060345, GO:0007186=PMID:16443932, GO:0034375=PMID:17438339, GO:0042157=Reactome:REACT_13621, GO:0006641=PMID:17142127, GO:0006642=GO_REF:0000019, GO:0045833=PMID:182536, GO:0006629=Reactome:REACT_602, GO:0050995=PMID:15576844, GO:0042627=PMID:8245722, GO:0043434=GO_REF:0000019, GO:0070328=PMID:18767813, GO:0044281=Reactome:REACT_111217, GO:0034379=PMID:18399797, GO:0008289=GO_REF:0000002, GO:0006954=GO_REF:0000019, GO:0005543=PMID:11060345, GO:0034382=PMID:4020294, GO:0015485=PMID:11162594, GO:0070653=PMID:9254056, GO:0030234=PMID:11060345, GO:0060621=PMID:15778093, GO:0008203=GO_REF:0000019, GO:0032489=PMID:16443932, GO:0007584=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0045717=PMID:11060345, GO:0005576=Reactome:REACT_160272, GO:0001523=Reactome:REACT_24968, GO:0010916=PMID:1917954, GO:0033700=PMID:11162594, GO:0048261=PMID:1917954, GO:0006869=GO_REF:0000002, GO:0005769=Reactome:REACT_160272} P02656 Apolipoprotein C-III protein 20080402 {GO:0007603=TAS, GO:0010897=IDA, GO:0010903=IC, GO:0005615=IDA, GO:0034361=IDA, GO:0042953=IEA, GO:0010987=IMP, GO:0034363=IDA, GO:0019433=IDA, GO:0010989=IMP, GO:0055102=IDA, GO:0042632=IMP, GO:0033344=IDA, GO:0043691=IC, GO:0034366=IDA, GO:0051005=IDA, GO:0007186=IDA, GO:0034375=IMP, GO:0042157=TAS, GO:0006641=IMP, GO:0006642=IEA, GO:0045833=IDA, GO:0006629=TAS, GO:0050995=IDA, GO:0042627=IDA, GO:0043434=IEA, GO:0070328=IMP, GO:0044281=TAS, GO:0034379=TAS, GO:0008289=IEA, GO:0006954=IEA, GO:0005543=IDA, GO:0034382=IDA, GO:0015485=IC, GO:0070653=IPI, GO:0030234=IDA, GO:0060621=IMP, GO:0008203=IEA, GO:0032489=IDA, GO:0007584=IEA, GO:0042493=IEA, GO:0045717=IDA, GO:0005576=TAS, GO:0001523=TAS, GO:0010916=IDA, GO:0033700=IDA, GO:0048261=IDA, GO:0006869=IEA, GO:0005769=TAS} G-protein coupled receptor signaling pathway, cholesterol efflux, cholesterol homeostasis, cholesterol metabolic process, chylomicron remnant clearance, high-density lipoprotein particle remodeling, inflammatory response, lipid metabolic process, lipid transport, lipoprotein metabolic process, lipoprotein transport, negative regulation of cholesterol import, negative regulation of fatty acid biosynthetic process, negative regulation of high-density lipoprotein particle clearance, negative regulation of lipid catabolic process, negative regulation of lipid metabolic process, negative regulation of lipoprotein lipase activity, negative regulation of low-density lipoprotein particle clearance, negative regulation of receptor-mediated endocytosis, negative regulation of triglyceride catabolic process, negative regulation of very-low-density lipoprotein particle clearance, negative regulation of very-low-density lipoprotein particle remodeling, phospholipid efflux, phototransduction, visible light, regulation of Cdc42 protein signal transduction, response to drug, response to nutrient, response to peptide hormone stimulus, retinoid metabolic process, reverse cholesterol transport, small molecule metabolic process, triglyceride catabolic process, triglyceride homeostasis, triglyceride metabolic process, triglyceride mobilization, very-low-density lipoprotein particle assembly chylomicron, early endosome, extracellular region, extracellular space, intermediate-density lipoprotein particle, spherical high-density lipoprotein particle, very-low-density lipoprotein particle cholesterol binding, enzyme regulator activity, high-density lipoprotein particle receptor binding, lipase inhibitor activity, lipid binding, phospholipid binding Human APOC4 BHF-UCL UniProtKB {GO:0034361=PMID:12700345, GO:0006629=PMID:8530039, GO:0034364=PMID:12700345, GO:0010890=PMID:18809223, GO:0070328=PMID:8827523, GO:0005319=PMID:8530039} P55056 Apolipoprotein C-IV protein 20090528 {GO:0034361=IDA, GO:0006629=TAS, GO:0034364=IDA, GO:0010890=IMP, GO:0070328=IMP, GO:0005319=TAS} lipid metabolic process, positive regulation of sequestering of triglyceride, triglyceride homeostasis high-density lipoprotein particle, very-low-density lipoprotein particle lipid transporter activity Human APOD GOC UniProtKB {GO:0006629=PMID:19176353, GO:0005515=PMID:7918467, GO:0005215=GO_REF:0000002, GO:0048471=PMID:14551159, GO:0005783=GO_REF:0000024, GO:0042246=GO_REF:0000024, GO:0048678=GO_REF:0000024, GO:0071638=PMID:18842892, GO:0005615=PMID:21705670, GO:0030425=GO_REF:0000024, GO:0008289=GO_REF:0000002, GO:0051895=PMID:21705670, GO:0005622=GO_REF:0000019, GO:0015485=PMID:9278274, GO:0014012=GO_REF:0000024, GO:0043025=GO_REF:0000024, GO:0006006=PMID:19176353, GO:0010642=PMID:14551159, GO:2000405=PMID:18842892, GO:0060588=GO_REF:0000019, GO:0042493=GO_REF:0000024, GO:0007568=PMID:20023409, GO:0036094=GO_REF:0000002, GO:0005576=PMID:14718574, GO:0001525=PMID:21705670, GO:0022626=GO_REF:0000024, GO:0007420=GO_REF:0000024, GO:0006869=PMID:3453108, GO:1900016=PMID:18842892, GO:0000302=PMID:18419796, GO:0005319=PMID:3453108} P05090 Apolipoprotein D protein 20130413 {GO:0006629=IDA, GO:0005515=IPI, GO:0005215=IEA, GO:0048471=IDA, GO:0005783=ISS, GO:0042246=ISS, GO:0048678=ISS, GO:0071638=IDA, GO:0005615=IDA, GO:0030425=ISS, GO:0008289=IEA, GO:0051895=IMP, GO:0005622=IEA, GO:0015485=IDA, GO:0014012=ISS, GO:0043025=ISS, GO:0006006=IDA, GO:0010642=IDA, GO:2000405=IDA, GO:0060588=IEA, GO:0042493=ISS, GO:0007568=NAS, GO:0036094=IEA, GO:0005576=NAS, GO:0001525=NAS, GO:0022626=ISS, GO:0007420=ISS, GO:0006869=NAS, GO:1900016=IDA, GO:0000302=IDA, GO:0005319=NAS} aging, angiogenesis, brain development, glucose metabolic process, lipid metabolic process, lipid transport, negative regulation of T cell migration, negative regulation of cytokine production involved in inflammatory response, negative regulation of focal adhesion assembly, negative regulation of lipoprotein lipid oxidation, negative regulation of monocyte chemotactic protein-1 production, negative regulation of platelet-derived growth factor receptor signaling pathway, peripheral nervous system axon regeneration, response to axon injury, response to drug, response to reactive oxygen species, tissue regeneration cytosolic ribosome, dendrite, endoplasmic reticulum, extracellular region, extracellular space, intracellular, neuronal cell body, perinuclear region of cytoplasm cholesterol binding, lipid binding, lipid transporter activity, protein binding, small molecule binding, transporter activity Human APOE BHF-UCL UniProtKB {GO:0005515=PMID:21593558, GO:0048709=GO_REF:0000019, GO:0046911=PMID:9685360, GO:0048844=GO_REF:0000019, GO:0034361=PMID:17154273, GO:0071397=GO_REF:0000019, GO:0034364=PMID:210174, GO:0034363=PMID:17336988, GO:0034362=PMID:8245722, GO:0034447=PMID:9649566, GO:0042632=PMID:9649566, GO:0032868=GO_REF:0000019, GO:0005794=GO_REF:0000019, GO:0046982=PMID:8245722, GO:0007271=PMID:9622609, GO:0034372=PMID:12401887, GO:0034374=GO_REF:0000019, GO:0051000=PMID:8995232, GO:0034375=PMID:12401887, GO:0006641=PMID:9649566, GO:0005319=PMID:17305370, GO:0010544=PMID:8995232, GO:0006629=Reactome:REACT_602, GO:0045471=GO_REF:0000019, GO:0045541=PMID:1917954, GO:0010873=PMID:15654758, GO:0042627=PMID:16935699, GO:0044281=Reactome:REACT_111217, GO:0070326=PMID:1384047, GO:0019934=PMID:8995232, GO:0030425=PMID:8083695, GO:0010875=PMID:12401887, GO:0034384=PMID:210175, GO:0034382=PMID:7175379, GO:0014012=GO_REF:0000019, GO:0042311=GO_REF:0000019, GO:0007010=PMID:9622609, GO:0034380=PMID:17305370, GO:0032526=GO_REF:0000019, GO:0032489=PMID:16443932, GO:0005770=GO_REF:0000019, GO:0048156=PMID:7566652, GO:0046907=PMID:9622609, GO:0005576=Reactome:REACT_160272, GO:0032805=PMID:15950758, GO:0071363=GO_REF:0000019, GO:0050728=PMID:8995232, GO:0030195=PMID:8995232, GO:0030828=PMID:8995232, GO:0005769=Reactome:REACT_160272, GO:0010468=GO_REF:0000019, GO:0008219=GO_REF:0000037, GO:0006707=GO_REF:0000019, GO:0007603=Reactome:REACT_160125, GO:0002021=GO_REF:0000019, GO:0042803=PMID:8245722, GO:0042802=PMID:4066713, GO:0043524=GO_REF:0000019, GO:0048168=PMID:9622609, GO:0046848=GO_REF:0000019, GO:0043025=PMID:8083695, GO:0006979=GO_REF:0000019, GO:0033344=PMID:11162594, GO:0016209=PMID:9685360, GO:0007568=GO_REF:0000019, GO:0043691=PMID:8127890, GO:0031232=GO_REF:0000019, GO:0006898=PMID:1917954, GO:0051651=GO_REF:0000019, GO:0007186=PMID:16443932, GO:0071347=GO_REF:0000019, GO:0042157=Reactome:REACT_13621, GO:0000302=PMID:11743999, GO:0042159=GO_REF:0000019, GO:0043537=PMID:9685360, GO:0042158=GO_REF:0000019, GO:0051044=PMID:15950758, GO:0005886=Reactome:REACT_6849, GO:0007263=PMID:8995232, GO:0017127=GO_REF:0000019, GO:0045773=GO_REF:0000019, GO:0008289=PMID:4066713, GO:0060228=PMID:15654758, GO:0005737=PMID:8083695, GO:0030516=PMID:9622609, GO:0001540=PMID:11305869, GO:0005543=PMID:4066713, GO:0043407=PMID:9685360, GO:0008201=PMID:2745454, GO:0008203=PMID:9649566, GO:0071813=GO_REF:0000019, GO:0043066=PMID:9685360, GO:0006874=GO_REF:0000019, GO:0006917=PMID:12753088, GO:0001523=Reactome:REACT_24968, GO:0033700=PMID:11162594, GO:0001937=PMID:9685360, GO:0006869=GO_REF:0000038, GO:0050750=PMID:17326667} P02649 Apolipoprotein E protein 20080402 {GO:0005515=IPI, GO:0048709=IEA, GO:0046911=IDA, GO:0048844=IEA, GO:0034361=IDA, GO:0071397=IEA, GO:0034364=IDA, GO:0034363=IDA, GO:0034362=IDA, GO:0034447=IMP, GO:0042632=IDA, GO:0032868=IEA, GO:0005794=IEA, GO:0046982=IPI, GO:0007271=TAS, GO:0034372=IGI, GO:0034374=IEA, GO:0051000=IDA, GO:0034375=IGI, GO:0006641=IDA, GO:0005319=IDA, GO:0010544=IDA, GO:0006629=TAS, GO:0045471=IEA, GO:0045541=IDA, GO:0010873=IDA, GO:0042627=IDA, GO:0044281=TAS, GO:0070326=IDA, GO:0019934=IDA, GO:0030425=NAS, GO:0010875=IGI, GO:0034384=IDA, GO:0034382=IMP, GO:0014012=IEA, GO:0042311=IEA, GO:0007010=TAS, GO:0034380=IDA, GO:0032526=IEA, GO:0032489=IDA, GO:0005770=IEA, GO:0048156=IPI, GO:0046907=TAS, GO:0005576=TAS, GO:0032805=IDA, GO:0071363=IEA, GO:0050728=IC, GO:0030195=IDA, GO:0030828=IDA, GO:0005769=TAS, GO:0010468=IEA, GO:0008219=IEA, GO:0006707=IEA, GO:0007603=TAS, GO:0002021=IEA, GO:0042803=IDA, GO:0042802=IDA, GO:0043524=IEA, GO:0048168=TAS, GO:0046848=IEA, GO:0043025=NAS, GO:0006979=IEA, GO:0033344=IDA, GO:0016209=IDA, GO:0007568=IEA, GO:0043691=IDA, GO:0031232=IEA, GO:0006898=IDA, GO:0051651=IEA, GO:0007186=IDA, GO:0071347=IEA, GO:0042157=TAS, GO:0000302=NAS, GO:0042159=IEA, GO:0043537=IDA, GO:0042158=IEA, GO:0051044=IDA, GO:0005886=TAS, GO:0007263=IDA, GO:0017127=IEA, GO:0045773=IEA, GO:0008289=IDA, GO:0060228=IDA, GO:0005737=NAS, GO:0030516=TAS, GO:0001540=IDA, GO:0005543=IDA, GO:0043407=IDA, GO:0008201=IDA, GO:0008203=IDA, GO:0071813=IEA, GO:0043066=IDA, GO:0006874=IEA, GO:0006917=IDA, GO:0001523=TAS, GO:0033700=IDA, GO:0001937=IDA, GO:0006869=IEA, GO:0050750=IPI} G-protein coupled receptor signaling pathway, aging, artery morphogenesis, cGMP-mediated signaling, cell death, cellular calcium ion homeostasis, cellular response to cholesterol, cellular response to growth factor stimulus, cellular response to interleukin-1, cholesterol catabolic process, cholesterol efflux, cholesterol homeostasis, cholesterol metabolic process, chylomicron remnant clearance, cytoskeleton organization, high-density lipoprotein particle assembly, high-density lipoprotein particle clearance, high-density lipoprotein particle remodeling, induction of apoptosis, intracellular transport, lipid metabolic process, lipid transport, lipoprotein biosynthetic process, lipoprotein catabolic process, lipoprotein metabolic process, low-density lipoprotein particle remodeling, maintenance of location in cell, negative regulation of MAP kinase activity, negative regulation of apoptotic process, negative regulation of blood coagulation, negative regulation of blood vessel endothelial cell migration, negative regulation of cholesterol biosynthetic process, negative regulation of endothelial cell proliferation, negative regulation of inflammatory response, negative regulation of neuron apoptotic process, negative regulation of platelet activation, nitric oxide mediated signal transduction, oligodendrocyte differentiation, peripheral nervous system axon regeneration, phospholipid efflux, phototransduction, visible light, positive regulation of axon extension, positive regulation of cGMP biosynthetic process, positive regulation of cholesterol efflux, positive regulation of cholesterol esterification, positive regulation of low-density lipoprotein particle receptor catabolic process, positive regulation of membrane protein ectodomain proteolysis, positive regulation of nitric-oxide synthase activity, receptor-mediated endocytosis, regulation of Cdc42 protein signal transduction, regulation of axon extension, regulation of gene expression, regulation of neuronal synaptic plasticity, response to dietary excess, response to ethanol, response to insulin stimulus, response to oxidative stress, response to reactive oxygen species, response to retinoic acid, retinoid metabolic process, reverse cholesterol transport, small molecule metabolic process, synaptic transmission, cholinergic, triglyceride metabolic process, vasodilation, very-low-density lipoprotein particle clearance, very-low-density lipoprotein particle remodeling Golgi apparatus, chylomicron, cytoplasm, dendrite, early endosome, extracellular region, extrinsic to external side of plasma membrane, high-density lipoprotein particle, intermediate-density lipoprotein particle, late endosome, low-density lipoprotein particle, neuronal cell body, plasma membrane, very-low-density lipoprotein particle antioxidant activity, beta-amyloid binding, cholesterol transporter activity, heparin binding, hydroxyapatite binding, identical protein binding, lipid binding, lipid transporter activity, lipoprotein particle binding, low-density lipoprotein particle receptor binding, metal chelating activity, phosphatidylcholine-sterol O-acyltransferase activator activity, phospholipid binding, protein binding, protein heterodimerization activity, protein homodimerization activity, tau protein binding, very-low-density lipoprotein particle receptor binding Human APOF PINC UniProtKB {GO:0006629=PMID:8093033, GO:0033344=GO_REF:0000019, GO:0015485=PMID:6816269, GO:0034364=GO_REF:0000037, GO:0006869=PMID:6816269, GO:0034362=GO_REF:0000037, GO:0005102=PMID:8093033, GO:0006641=GO_REF:0000019, GO:0005576=PMID:14718574, GO:0005319=PMID:6816269, GO:0008203=GO_REF:0000019} Q13790 Apolipoprotein F protein 20030904 {GO:0006629=TAS, GO:0033344=IEA, GO:0015485=TAS, GO:0034364=IEA, GO:0006869=TAS, GO:0034362=IEA, GO:0005102=TAS, GO:0006641=IEA, GO:0005576=NAS, GO:0005319=TAS, GO:0008203=IEA} cholesterol efflux, cholesterol metabolic process, lipid metabolic process, lipid transport, triglyceride metabolic process extracellular region, high-density lipoprotein particle, low-density lipoprotein particle cholesterol binding, lipid transporter activity, receptor binding Human APOH BHF-UCL UniProtKB {GO:0005515=PMID:16480936, GO:0043499=PMID:16480936, GO:0042627=PMID:222615, GO:0005615=PMID:15486070, GO:0008289=PMID:222615, GO:0034361=PMID:222615, GO:0005543=PMID:15486070, GO:0001948=PMID:9269765, GO:0034364=PMID:222615, GO:0008201=GO_REF:0000037, GO:0033033=PMID:15534879, GO:0034197=PMID:7078428, GO:0009986=PMID:16480936, GO:0051918=PMID:14726399, GO:0051917=PMID:16480936, GO:0060230=PMID:7417307, GO:0010596=PMID:17872974, GO:0034392=PMID:15534879, GO:0030193=GO_REF:0000019, GO:0030194=PMID:16480936, GO:0001937=PMID:17872974, GO:0007597=PMID:4052628, GO:0030195=PMID:4052628, GO:0016525=PMID:17872974, GO:0006641=PMID:7417307, GO:0031639=PMID:16480936, GO:0051006=PMID:7417307} P02749 Beta-2-glycoprotein 1 protein 20080402 {GO:0005515=IPI, GO:0043499=IDA, GO:0042627=IDA, GO:0005615=IDA, GO:0008289=IDA, GO:0034361=IDA, GO:0005543=IDA, GO:0001948=IPI, GO:0034364=IDA, GO:0008201=IEA, GO:0033033=IDA, GO:0034197=ISS, GO:0009986=IDA, GO:0051918=IDA, GO:0051917=IDA, GO:0060230=IDA, GO:0010596=IDA, GO:0034392=IDA, GO:0030193=IEA, GO:0030194=TAS, GO:0001937=IDA, GO:0007597=IDA, GO:0030195=IDA, GO:0016525=IDA, GO:0006641=IDA, GO:0031639=IDA, GO:0051006=IDA} blood coagulation, intrinsic pathway, negative regulation of angiogenesis, negative regulation of blood coagulation, negative regulation of endothelial cell migration, negative regulation of endothelial cell proliferation, negative regulation of fibrinolysis, negative regulation of myeloid cell apoptotic process, negative regulation of smooth muscle cell apoptotic process, plasminogen activation, positive regulation of blood coagulation, positive regulation of lipoprotein lipase activity, regulation of blood coagulation, regulation of fibrinolysis, triglyceride metabolic process, triglyceride transport cell surface, chylomicron, extracellular space, high-density lipoprotein particle, very-low-density lipoprotein particle eukaryotic cell surface binding, glycoprotein binding, heparin binding, lipid binding, lipoprotein lipase activator activity, phospholipid binding, protein binding Human APOL1 BHF-UCL UniProtKB {GO:0005515=PMID:12621437, GO:0006821=PMID:16020735, GO:0031224=PMID:16020735, GO:0005576=Reactome:REACT_160200, GO:0005615=PMID:17192540, GO:0005254=PMID:16020735, GO:0008289=PMID:16020735, GO:0034361=PMID:17154273, GO:0034364=PMID:9325276, GO:0045087=PMID:17192540, GO:0006869=GO_REF:0000037, GO:0019835=PMID:12621437, GO:0042157=GO_REF:0000002, GO:0031640=PMID:12621437, GO:0008203=GO_REF:0000037} O14791 Apolipoprotein L1 protein 20080403 {GO:0005515=IPI, GO:0006821=IDA, GO:0031224=IC, GO:0005576=TAS, GO:0005615=IDA, GO:0005254=IDA, GO:0008289=IDA, GO:0034361=IDA, GO:0034364=IDA, GO:0045087=IDA, GO:0006869=IEA, GO:0019835=IDA, GO:0042157=IEA, GO:0031640=IDA, GO:0008203=IEA} chloride transport, cholesterol metabolic process, cytolysis, innate immune response, killing of cells of other organism, lipid transport, lipoprotein metabolic process extracellular region, extracellular space, high-density lipoprotein particle, intrinsic to membrane, very-low-density lipoprotein particle chloride channel activity, lipid binding, protein binding Human GO:0005254 APOL2 UniProtKB UniProtKB {GO:0006629=PMID:11944986, GO:0008035=PMID:11374903, GO:0060135=PMID:11374903, GO:0006869=PMID:11374903, GO:0005789=PMID:11374903, GO:0005102=PMID:11374903, GO:0042157=GO_REF:0000002, GO:0007275=PMID:11374903, GO:0005576=GO_REF:0000002, GO:0006953=PMID:11374903, GO:0008203=PMID:11374903, GO:0008289=PMID:11374903} Q9BQE5 Apolipoprotein L2 protein 20080408 {GO:0006629=NAS, GO:0008035=NAS, GO:0060135=NAS, GO:0006869=NAS, GO:0005789=NAS, GO:0005102=NAS, GO:0042157=IEA, GO:0007275=NAS, GO:0005576=IEA, GO:0006953=NAS, GO:0008203=NAS, GO:0008289=NAS} acute-phase response, cholesterol metabolic process, lipid metabolic process, lipid transport, lipoprotein metabolic process, maternal process involved in female pregnancy, multicellular organismal development endoplasmic reticulum membrane, extracellular region high-density lipoprotein particle binding, lipid binding, receptor binding Human APOL5 UniProtKB UniProtKB {GO:0008035=PMID:11374903, GO:0006629=PMID:11374903, GO:0005737=GO_REF:0000039, GO:0006869=GO_REF:0000037, GO:0042157=GO_REF:0000002, GO:0005576=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0008289=GO_REF:0000002} Q9BWW9 Apolipoprotein L5 protein 20061026 {GO:0008035=NAS, GO:0006629=NAS, GO:0005737=IEA, GO:0006869=IEA, GO:0042157=IEA, GO:0005576=IEA, GO:0005575=ND, GO:0008289=IEA} lipid metabolic process, lipid transport, lipoprotein metabolic process cellular_component, cytoplasm, extracellular region high-density lipoprotein particle binding, lipid binding Human APOL6 UniProtKB UniProtKB {GO:0005737=GO_REF:0000029, GO:0006869=GO_REF:0000029, GO:0042157=GO_REF:0000002, GO:0005576=GO_REF:0000002, GO:0005319=GO_REF:0000029, GO:0008289=GO_REF:0000002} Q9BWW8 Apolipoprotein L6 protein 20021105 {GO:0005737=NAS, GO:0006869=NAS, GO:0042157=IEA, GO:0005576=IEA, GO:0005319=NAS, GO:0008289=IEA} lipid transport, lipoprotein metabolic process cytoplasm, extracellular region lipid binding, lipid transporter activity Human APOLD1 UniProtKB UniProtKB {GO:0001666=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0006869=GO_REF:0000002, GO:0042157=GO_REF:0000002, GO:0042118=GO_REF:0000019, GO:0005576=GO_REF:0000002, GO:0001525=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0045601=GO_REF:0000019, GO:0008289=GO_REF:0000002} Q96LR9 Apolipoprotein L domain-containing protein 1 protein 20130413 {GO:0001666=IEA, GO:0005886=IEA, GO:0006869=IEA, GO:0042157=IEA, GO:0042118=IEA, GO:0005576=IEA, GO:0001525=IEA, GO:0016021=IEA, GO:0030154=IEA, GO:0045601=IEA, GO:0008289=IEA} angiogenesis, cell differentiation, endothelial cell activation, lipid transport, lipoprotein metabolic process, regulation of endothelial cell differentiation, response to hypoxia extracellular region, integral to membrane, plasma membrane lipid binding Human UniProtKB-SubCell:SL-0039 APOM BHF-UCL UniProtKB {GO:0042632=PMID:15793583, GO:0033344=PMID:15793583, GO:0016209=PMID:22204862, GO:0043691=PMID:15793583, GO:0034366=PMID:16682745, GO:0009749=GO_REF:0000019, GO:0034361=PMID:17154273, GO:0005543=PMID:22204862, GO:0034384=PMID:15793583, GO:0034365=PMID:15793583, GO:0034364=PMID:22204862, GO:0005887=PMID:10531326, GO:0034375=PMID:18006500, GO:0034362=PMID:16682745, GO:0034380=PMID:15793583, GO:0034445=PMID:22204862, GO:0042157=GO_REF:0000019, GO:0005319=PMID:16682745} O95445 Apolipoprotein M protein 20120531 {GO:0042632=IC, GO:0033344=IMP, GO:0016209=IDA, GO:0043691=ISS, GO:0034366=IDA, GO:0009749=IEA, GO:0034361=IDA, GO:0005543=IDA, GO:0034384=ISS, GO:0034365=IDA, GO:0034364=IDA, GO:0005887=TAS, GO:0034375=IMP, GO:0034362=IDA, GO:0034380=ISS, GO:0034445=IDA, GO:0042157=IEA, GO:0005319=IDA} cholesterol efflux, cholesterol homeostasis, high-density lipoprotein particle assembly, high-density lipoprotein particle clearance, high-density lipoprotein particle remodeling, lipoprotein metabolic process, negative regulation of plasma lipoprotein particle oxidation, response to glucose stimulus, reverse cholesterol transport discoidal high-density lipoprotein particle, high-density lipoprotein particle, integral to plasma membrane, low-density lipoprotein particle, spherical high-density lipoprotein particle, very-low-density lipoprotein particle antioxidant activity, lipid transporter activity, phospholipid binding Human APOO BHF-UCL UniProtKB {GO:0034361=GO_REF:0000037, GO:0034364=GO_REF:0000037, GO:0034362=GO_REF:0000037, GO:0006869=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005615=PMID:22261194} Q9BUR5 Apolipoprotein O protein 20120228 {GO:0034361=IEA, GO:0034364=IEA, GO:0034362=IEA, GO:0006869=IEA, GO:0016021=IEA, GO:0005615=ISS} lipid transport extracellular space, high-density lipoprotein particle, integral to membrane, low-density lipoprotein particle, very-low-density lipoprotein particle Human UniProtKB:F1SPZ9 APOOL UniProtKB UniProtKB {GO:0005743=GO_REF:0000019, GO:0005576=GO_REF:0000039} Q6UXV4 Apolipoprotein O-like protein 20130413 {GO:0005743=IEA, GO:0005576=IEA} extracellular region, mitochondrial inner membrane Human UniProtKB-SubCell:SL-0243 APOPT1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0043280=GO_REF:0000019, GO:0090200=GO_REF:0000019, GO:0034393=GO_REF:0000019, GO:0097193=GO_REF:0000019} Q96IL0 Apoptogenic protein 1, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0043280=IEA, GO:0090200=IEA, GO:0034393=IEA, GO:0097193=IEA} intrinsic apoptotic signaling pathway, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of release of cytochrome c from mitochondria, positive regulation of smooth muscle cell apoptotic process mitochondrion Human UniProtKB-SubCell:SL-0173 APP BHF-UCL UniProtKB {GO:0005515=PMID:19849849, GO:0031594=GO_REF:0000019, GO:0046914=GO_REF:0000002, GO:0045202=PMID:11988176, GO:0007409=GO_REF:0000024, GO:0051402=PMID:19225519, GO:0031175=GO_REF:0000024, GO:0043231=GO_REF:0000052, GO:0006878=GO_REF:0000024, GO:0007219=GO_REF:0000037, GO:0030198=GO_REF:0000024, GO:0007176=GO_REF:0000024, GO:0050885=GO_REF:0000019, GO:0006979=GO_REF:0000019, GO:0006378=GO_REF:0000024, GO:0005794=GO_REF:0000052, GO:0009986=PMID:7593229, GO:0007617=GO_REF:0000024, GO:0043393=GO_REF:0000019, GO:0050803=GO_REF:0000024, GO:0030168=Reactome:REACT_798, GO:0016358=GO_REF:0000024, GO:0006897=GO_REF:0000024, GO:0016504=GO_REF:0000019, GO:0035235=GO_REF:0000024, GO:0045931=GO_REF:0000024, GO:0005887=PMID:10806211, GO:0045087=Reactome:REACT_6802, GO:0008542=GO_REF:0000024, GO:0008088=GO_REF:0000024, GO:0008344=GO_REF:0000024, GO:0030424=GO_REF:0000024, GO:0048471=GO_REF:0000019, GO:0005886=PMID:12805363, GO:0004867=PMID:10652580, GO:0051425=PMID:12805363, GO:0051233=GO_REF:0000019, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_75877, GO:0016322=GO_REF:0000024, GO:0000085=GO_REF:0000024, GO:0005737=PMID:18509662, GO:0051563=GO_REF:0000019, GO:0001967=GO_REF:0000019, GO:0070851=GO_REF:0000019, GO:0043197=PMID:11988176, GO:0043198=PMID:11988176, GO:0016199=GO_REF:0000024, GO:0048669=GO_REF:0000024, GO:0045944=GO_REF:0000019, GO:0040014=GO_REF:0000024, GO:0031093=Reactome:REACT_21351, GO:0007626=GO_REF:0000024, GO:0007155=GO_REF:0000037, GO:0008201=GO_REF:0000037, GO:0008203=GO_REF:0000019, GO:0005102=PMID:19849849, GO:0045177=GO_REF:0000019, GO:0005576=Reactome:REACT_75905, GO:0006917=GO_REF:0000019, GO:0003677=GO_REF:0000024, GO:0006417=GO_REF:0000024, GO:0005905=GO_REF:0000039, GO:0045665=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0035253=GO_REF:0000019, GO:0002576=Reactome:REACT_318, GO:0051124=GO_REF:0000019, GO:0006468=GO_REF:0000024, GO:0030900=GO_REF:0000019, GO:0016021=GO_REF:0000024} P05067 Amyloid beta A4 protein protein 20101122 {GO:0005515=IPI, GO:0031594=IEA, GO:0046914=IEA, GO:0045202=IDA, GO:0007409=ISS, GO:0051402=IMP, GO:0031175=ISS, GO:0043231=IDA, GO:0006878=ISS, GO:0007219=IEA, GO:0030198=ISS, GO:0007176=ISS, GO:0050885=IEA, GO:0006979=IEA, GO:0006378=ISS, GO:0005794=IDA, GO:0009986=IDA, GO:0007617=ISS, GO:0043393=IEA, GO:0050803=ISS, GO:0030168=TAS, GO:0016358=ISS, GO:0006897=ISS, GO:0016504=IEA, GO:0035235=ISS, GO:0045931=ISS, GO:0005887=TAS, GO:0045087=TAS, GO:0008542=ISS, GO:0008088=ISS, GO:0008344=ISS, GO:0030424=ISS, GO:0048471=IEA, GO:0005886=IDA, GO:0004867=IDA, GO:0051425=IPI, GO:0051233=IEA, GO:0035872=TAS, GO:0005829=TAS, GO:0016322=ISS, GO:0000085=ISS, GO:0005737=IDA, GO:0051563=IEA, GO:0001967=IEA, GO:0070851=IEA, GO:0043197=IDA, GO:0043198=IDA, GO:0016199=ISS, GO:0048669=ISS, GO:0045944=IEA, GO:0040014=ISS, GO:0031093=TAS, GO:0007626=ISS, GO:0007155=IEA, GO:0008201=IEA, GO:0008203=IEA, GO:0005102=IPI, GO:0045177=IEA, GO:0005576=TAS, GO:0006917=IEA, GO:0003677=ISS, GO:0006417=ISS, GO:0005905=IEA, GO:0045665=IEA, GO:0007596=TAS, GO:0035253=IEA, GO:0002576=TAS, GO:0051124=IEA, GO:0006468=ISS, GO:0030900=IEA, GO:0016021=ISS} G2 phase of mitotic cell cycle, Notch signaling pathway, adult locomotory behavior, axon cargo transport, axon midline choice point recognition, axonogenesis, blood coagulation, cell adhesion, cellular copper ion homeostasis, cholesterol metabolic process, collateral sprouting in absence of injury, dendrite development, endocytosis, extracellular matrix organization, forebrain development, induction of apoptosis, innate immune response, ionotropic glutamate receptor signaling pathway, locomotory behavior, mRNA polyadenylation, mating behavior, negative regulation of neuron differentiation, neuromuscular process controlling balance, neuron apoptotic process, neuron projection development, neuron remodeling, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, platelet activation, platelet degranulation, positive regulation of mitotic cell cycle, positive regulation of transcription from RNA polymerase II promoter, protein phosphorylation, regulation of epidermal growth factor-activated receptor activity, regulation of multicellular organism growth, regulation of protein binding, regulation of synapse structure and activity, regulation of translation, response to oxidative stress, smooth endoplasmic reticulum calcium ion homeostasis, suckling behavior, synaptic growth at neuromuscular junction, visual learning Golgi apparatus, apical part of cell, axon, cell surface, ciliary rootlet, coated pit, cytoplasm, cytosol, dendritic shaft, dendritic spine, extracellular region, integral to membrane, integral to plasma membrane, intracellular membrane-bounded organelle, neuromuscular junction, perinuclear region of cytoplasm, plasma membrane, platelet alpha granule lumen, spindle midzone, synapse DNA binding, PTB domain binding, growth factor receptor binding, heparin binding, peptidase activator activity, protein binding, receptor binding, serine-type endopeptidase inhibitor activity, transition metal ion binding Human APPBP2 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0005737=PMID:11742091, GO:0005875=PMID:9843960, GO:0005874=GO_REF:0000037, GO:0046907=PMID:9843960, GO:0005634=PMID:11742091, GO:0003777=PMID:9843960, GO:0006886=PMID:9843960, GO:0030659=PMID:9843960} Q92624 Amyloid protein-binding protein 2 protein 20130415 {GO:0005515=IPI, GO:0005737=NAS, GO:0005875=TAS, GO:0005874=IEA, GO:0046907=IDA, GO:0005634=NAS, GO:0003777=TAS, GO:0006886=TAS, GO:0030659=IDA} intracellular protein transport, intracellular transport cytoplasm, cytoplasmic vesicle membrane, microtubule, microtubule associated complex, nucleus microtubule motor activity, protein binding Human UniProtKB:Q9BT88 APPL1 BHF-UCL UniProtKB {GO:0008286=PMID:17848569, GO:0005515=PMID:16622416, GO:0012506=PMID:17848569, GO:0008283=PMID:15016378, GO:0006915=Reactome:REACT_578, GO:0005634=PMID:15016378, GO:0042981=Reactome:REACT_13648, GO:0043422=PMID:17848569, GO:0005829=PMID:17848569, GO:0007165=PMID:10490823, GO:0007049=GO_REF:0000037, GO:0005737=PMID:10490823, GO:0005543=GO_REF:0000002, GO:0046324=PMID:17848569, GO:0016581=PMID:15016378, GO:0031901=GO_REF:0000039, GO:0090003=PMID:17848569, GO:0010008=Reactome:REACT_22412} Q9UKG1 DCC-interacting protein 13-alpha protein 20090227 {GO:0008286=TAS, GO:0005515=IPI, GO:0012506=IDA, GO:0008283=IDA, GO:0006915=TAS, GO:0005634=IDA, GO:0042981=TAS, GO:0043422=IPI, GO:0005829=IDA, GO:0007165=TAS, GO:0007049=IEA, GO:0005737=IC, GO:0005543=IEA, GO:0046324=IMP, GO:0016581=IDA, GO:0031901=IEA, GO:0090003=IMP, GO:0010008=TAS} apoptotic process, cell cycle, cell proliferation, insulin receptor signaling pathway, regulation of apoptotic process, regulation of establishment of protein localization to plasma membrane, regulation of glucose import, signal transduction NuRD complex, cytoplasm, cytosol, early endosome membrane, endosome membrane, nucleus, vesicle membrane phospholipid binding, protein binding, protein kinase B binding Human UniProtKB:P47197 APPL2 HGNC UniProtKB {GO:0005515=PMID:17030088, GO:0007165=PMID:15016378, GO:0005737=PMID:15016378, GO:0007049=GO_REF:0000037, GO:0005543=GO_REF:0000002, GO:0016581=PMID:15016378, GO:0008283=PMID:15016378, GO:0031901=GO_REF:0000039, GO:0005634=PMID:15016378, GO:0010008=PMID:15016378} Q8NEU8 DCC-interacting protein 13-beta protein 20070503 {GO:0005515=IPI, GO:0007165=TAS, GO:0005737=IC, GO:0007049=IEA, GO:0005543=IEA, GO:0016581=IDA, GO:0008283=IDA, GO:0031901=IEA, GO:0005634=IDA, GO:0010008=IDA} cell cycle, cell proliferation, signal transduction NuRD complex, cytoplasm, early endosome membrane, endosome membrane, nucleus phospholipid binding, protein binding Human UniProtKB:Q9UKG1 APRT HPA UniProtKB {GO:0032869=GO_REF:0000019, GO:0016208=PMID:15196008, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0055086=Reactome:REACT_1698, GO:0044209=GO_REF:0000041, GO:0044281=Reactome:REACT_111217, GO:0002055=GO_REF:0000019, GO:0005829=Reactome:REACT_165, GO:0006166=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0006168=GO_REF:0000019, GO:0007595=GO_REF:0000019, GO:0006144=Reactome:REACT_522, GO:0043101=Reactome:REACT_1923, GO:0009116=GO_REF:0000002, GO:0007625=GO_REF:0000019, GO:0016740=GO_REF:0000038, GO:0003999=Reactome:REACT_165} P07741 Adenine phosphoribosyltransferase protein 20100326 {GO:0032869=IEA, GO:0016208=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0055086=TAS, GO:0044209=IEA, GO:0044281=TAS, GO:0002055=IEA, GO:0005829=TAS, GO:0006166=IEA, GO:0005737=IDA, GO:0006168=IEA, GO:0007595=IEA, GO:0006144=TAS, GO:0043101=TAS, GO:0009116=IEA, GO:0007625=IEA, GO:0016740=IEA, GO:0003999=TAS} AMP salvage, adenine salvage, cellular response to insulin stimulus, grooming behavior, lactation, nucleobase-containing small molecule metabolic process, nucleoside metabolic process, purine nucleobase metabolic process, purine ribonucleoside salvage, purine-containing compound salvage, small molecule metabolic process cytoplasm, cytosol, nucleolus, nucleus AMP binding, adenine binding, adenine phosphoribosyltransferase activity, transferase activity Human APTX IntAct UniProtKB {GO:0051219=PMID:20008512, GO:0003725=PMID:16547001, GO:0005515=PMID:15044383, GO:0008967=PMID:17519253, GO:0033699=PMID:16547001, GO:0042542=PMID:15044383, GO:0008219=GO_REF:0000037, GO:0000012=PMID:17519253, GO:0000790=PMID:20008512, GO:0005730=PMID:15044383, GO:0003824=GO_REF:0000002, GO:0006974=PMID:15044383, GO:0003684=PMID:14755728, GO:0005737=GO_REF:0000039, GO:0003690=PMID:16547001, GO:0047485=PMID:16777843, GO:0031647=PMID:16777843, GO:0003682=PMID:15044383, GO:0008270=GO_REF:0000002, GO:0005654=PMID:16777843, GO:0000785=PMID:15044383, GO:0006266=GO_REF:0000019} Q7Z2E3 Aprataxin protein 20130415 {GO:0051219=IPI, GO:0003725=IDA, GO:0005515=IPI, GO:0008967=IDA, GO:0033699=IDA, GO:0042542=IDA, GO:0008219=IEA, GO:0000012=IDA, GO:0000790=IDA, GO:0005730=IDA, GO:0003824=IEA, GO:0006974=IMP, GO:0003684=IDA, GO:0005737=IEA, GO:0003690=IDA, GO:0047485=IPI, GO:0031647=IMP, GO:0003682=IDA, GO:0008270=IEA, GO:0005654=IDA, GO:0000785=IDA, GO:0006266=IEA} DNA ligation, cell death, regulation of protein stability, response to DNA damage stimulus, response to hydrogen peroxide, single strand break repair chromatin, cytoplasm, nuclear chromatin, nucleolus, nucleoplasm DNA 5'-adenosine monophosphate hydrolase activity, catalytic activity, chromatin binding, damaged DNA binding, double-stranded DNA binding, double-stranded RNA binding, phosphoglycolate phosphatase activity, phosphoprotein binding, protein N-terminus binding, protein binding, zinc ion binding Human UniProtKB:P09874 AQP1 GOC UniProtKB {GO:0005515=PMID:19447967, GO:0015079=GO_REF:0000024, GO:0005215=GO_REF:0000002, GO:0020003=GO_REF:0000024, GO:0070301=PMID:19424603, GO:0071732=PMID:14561230, GO:0071300=PMID:19424603, GO:0020005=PMID:18665841, GO:0031526=PMID:9013443, GO:0030157=PMID:12801959, GO:0035377=PMID:12766090, GO:0006884=PMID:11922632, GO:0034644=PMID:19424603, GO:0009925=PMID:17409744, GO:0015793=PMID:8584435, GO:0006833=Reactome:REACT_24023, GO:0005223=PMID:14561230, GO:0071474=PMID:11922632, GO:0031965=PMID:17645239, GO:0030950=PMID:19584911, GO:0071288=PMID:9321919, GO:0015696=PMID:19273840, GO:0071472=PMID:18509662, GO:0005267=PMID:11914159, GO:0033554=PMID:19268465, GO:0035378=PMID:17012249, GO:0035379=Reactome:REACT_121218, GO:0046878=PMID:15727941, GO:0005887=PMID:1722319, GO:0006182=PMID:14561230, GO:0085018=PMID:18665841, GO:0015701=Reactome:REACT_121380, GO:0071241=PMID:14561230, GO:0071280=PMID:8584435, GO:0005886=GO_REF:0000052, GO:0005634=PMID:17645239, GO:0044281=Reactome:REACT_111217, GO:0048146=PMID:16565507, GO:0016323=PMID:12801959, GO:0005737=PMID:18509662, GO:0016324=PMID:12801959, GO:0030184=PMID:16682607, GO:0030185=PMID:16682607, GO:0015250=Reactome:REACT_23841, GO:0042476=PMID:12522663, GO:0005372=PMID:9321919, GO:0006813=GO_REF:0000024, GO:0071805=PMID:11914159, GO:0043066=PMID:16565507, GO:0019725=PMID:19268465, GO:0042493=PMID:12172703, GO:0022857=PMID:17012249, GO:0071456=PMID:18275976, GO:0045177=PMID:14675051, GO:0015670=PMID:12745312, GO:0055085=Reactome:REACT_15518, GO:0045766=PMID:18275976, GO:0005903=PMID:16133142, GO:0042383=PMID:17409744, GO:0015168=PMID:8584435, GO:0021670=PMID:16133142, GO:0050891=PMID:17645239, GO:0051739=PMID:19273840, GO:0003097=PMID:9096382, GO:0033326=PMID:16814974, GO:0016021=GO_REF:0000038, GO:0071260=PMID:19268465, GO:0071320=PMID:18538351, GO:0071549=PMID:16711029} P29972 Aquaporin-1 protein 20130413 {GO:0005515=IPI, GO:0015079=ISS, GO:0005215=IEA, GO:0020003=ISS, GO:0070301=IDA, GO:0071732=IDA, GO:0071300=IDA, GO:0020005=IDA, GO:0031526=IDA, GO:0030157=IEP, GO:0035377=IDA, GO:0006884=IMP, GO:0034644=IDA, GO:0009925=IDA, GO:0015793=IDA, GO:0006833=TAS, GO:0005223=IDA, GO:0071474=IMP, GO:0031965=IDA, GO:0030950=IMP, GO:0071288=IDA, GO:0015696=IDA, GO:0071472=IDA, GO:0005267=IMP, GO:0033554=IDA, GO:0035378=IDA, GO:0035379=TAS, GO:0046878=IMP, GO:0005887=TAS, GO:0006182=IDA, GO:0085018=IMP, GO:0015701=TAS, GO:0071241=IDA, GO:0071280=IDA, GO:0005886=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0048146=IDA, GO:0016323=IDA, GO:0005737=IDA, GO:0016324=IDA, GO:0030184=IDA, GO:0030185=IDA, GO:0015250=EXP, GO:0042476=IEP, GO:0005372=IDA, GO:0006813=ISS, GO:0071805=IMP, GO:0043066=IDA, GO:0019725=IDA, GO:0042493=IDA, GO:0022857=IDA, GO:0071456=IDA, GO:0045177=IDA, GO:0015670=IDA, GO:0055085=TAS, GO:0045766=IMP, GO:0005903=IDA, GO:0042383=IDA, GO:0015168=IDA, GO:0021670=IEP, GO:0050891=IEP, GO:0051739=IDA, GO:0003097=IDA, GO:0033326=IEP, GO:0016021=IEA, GO:0071260=IDA, GO:0071320=IDA, GO:0071549=IDA} ammonium transport, bicarbonate transport, cGMP biosynthetic process, carbon dioxide transmembrane transport, carbon dioxide transport, cell volume homeostasis, cellular homeostasis, cellular hyperosmotic response, cellular response to UV, cellular response to cAMP, cellular response to copper ion, cellular response to dexamethasone stimulus, cellular response to hydrogen peroxide, cellular response to hypoxia, cellular response to inorganic substance, cellular response to mechanical stimulus, cellular response to mercury ion, cellular response to nitric oxide, cellular response to retinoic acid, cellular response to salt stress, cellular response to stress, cerebrospinal fluid secretion, establishment or maintenance of actin cytoskeleton polarity, glycerol transport, lateral ventricle development, maintenance of symbiont-containing vacuole by host, multicellular organismal water homeostasis, negative regulation of apoptotic process, nitric oxide transport, odontogenesis, pancreatic juice secretion, positive regulation of angiogenesis, positive regulation of fibroblast proliferation, positive regulation of saliva secretion, potassium ion transmembrane transport, potassium ion transport, renal water transport, response to drug, small molecule metabolic process, transepithelial water transport, transmembrane transport, water transport apical part of cell, apical plasma membrane, basal plasma membrane, basolateral plasma membrane, brush border, brush border membrane, cytoplasm, integral to membrane, integral to plasma membrane, nuclear membrane, nucleus, plasma membrane, sarcolemma, symbiont-containing vacuole, symbiont-containing vacuole membrane ammonia transmembrane transporter activity, carbon dioxide transmembrane transporter activity, glycerol transmembrane transporter activity, intracellular cGMP activated cation channel activity, nitric oxide transmembrane transporter activity, potassium channel activity, potassium ion transmembrane transporter activity, protein binding, transmembrane transporter activity, transporter activity, water channel activity, water transmembrane transporter activity Human AQP11 Reactome UniProtKB {GO:0005215=GO_REF:0000002, GO:0005886=Reactome:REACT_23858, GO:0009986=PMID:16650285, GO:0001822=GO_REF:0000019, GO:0005783=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0030425=GO_REF:0000019, GO:0015840=PMID:16650285, GO:0005829=GO_REF:0000019, GO:0003674=GO_REF:0000015, GO:0048388=GO_REF:0000019, GO:0015793=PMID:16650285, GO:0051260=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0006833=Reactome:REACT_23887, GO:0006811=PMID:16650285} Q8NBQ7 Aquaporin-11 protein 20090808 {GO:0005215=IEA, GO:0005886=TAS, GO:0009986=IDA, GO:0001822=IEA, GO:0005783=IEA, GO:0055085=TAS, GO:0030425=IEA, GO:0015840=IDA, GO:0005829=IEA, GO:0003674=ND, GO:0048388=IEA, GO:0015793=IDA, GO:0051260=IEA, GO:0016021=IEA, GO:0006833=TAS, GO:0006811=IDA} endosomal lumen acidification, glycerol transport, ion transport, kidney development, protein homooligomerization, transmembrane transport, urea transport, water transport cell surface, cytosol, dendrite, endoplasmic reticulum, integral to membrane, plasma membrane molecular_function, transporter activity Human AQP2 Reactome UniProtKB {GO:0005802=GO_REF:0000019, GO:0071280=PMID:8584435, GO:0005215=GO_REF:0000002, GO:0009651=GO_REF:0000019, GO:0005886=Reactome:REACT_23863, GO:0051928=GO_REF:0000019, GO:0030136=GO_REF:0000019, GO:0005764=GO_REF:0000019, GO:0006884=GO_REF:0000019, GO:0016323=GO_REF:0000039, GO:0016324=GO_REF:0000024, GO:0042594=GO_REF:0000019, GO:0033762=GO_REF:0000019, GO:0015250=Reactome:REACT_23788, GO:0015793=PMID:8584435, GO:0005372=PMID:9321919, GO:0032496=GO_REF:0000019, GO:0030042=GO_REF:0000019, GO:0006833=Reactome:REACT_24023, GO:0030658=Reactome:REACT_23863, GO:0005791=GO_REF:0000019, GO:0007588=PMID:7532304, GO:0042631=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:0005794=GO_REF:0000039, GO:0071288=PMID:8584435, GO:0007568=GO_REF:0000019, GO:0006915=GO_REF:0000019, GO:0003779=GO_REF:0000019, GO:0006972=GO_REF:0000019, GO:0030165=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0072205=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0051592=GO_REF:0000019, GO:0015168=PMID:8584435, GO:0010226=GO_REF:0000019, GO:0003097=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0055037=GO_REF:0000019, GO:0070382=GO_REF:0000019, GO:0005769=GO_REF:0000019} P41181 Aquaporin-2 protein 20090812 {GO:0005802=IEA, GO:0071280=IDA, GO:0005215=IEA, GO:0009651=IEA, GO:0005886=TAS, GO:0051928=IEA, GO:0030136=IEA, GO:0005764=IEA, GO:0006884=IEA, GO:0016323=IEA, GO:0016324=ISS, GO:0042594=IEA, GO:0033762=IEA, GO:0015250=EXP, GO:0015793=IDA, GO:0005372=IDA, GO:0032496=IEA, GO:0030042=IEA, GO:0006833=TAS, GO:0030658=TAS, GO:0005791=IEA, GO:0007588=TAS, GO:0042631=IEA, GO:0007565=IEA, GO:0005794=IEA, GO:0071288=IDA, GO:0007568=IEA, GO:0006915=IEA, GO:0003779=IEA, GO:0006972=IEA, GO:0030165=IEA, GO:0055085=TAS, GO:0072205=IEA, GO:0043234=IEA, GO:0051592=IEA, GO:0015168=IDA, GO:0010226=IEA, GO:0003097=IEA, GO:0016021=IEA, GO:0055037=IEA, GO:0070382=IEA, GO:0005769=IEA} actin filament depolymerization, aging, apoptotic process, cell volume homeostasis, cellular response to copper ion, cellular response to mercury ion, cellular response to water deprivation, excretion, female pregnancy, glycerol transport, hyperosmotic response, metanephric collecting duct development, positive regulation of calcium ion transport, renal water transport, response to calcium ion, response to glucagon stimulus, response to lipopolysaccharide, response to lithium ion, response to salt stress, response to starvation, transmembrane transport, water transport Golgi apparatus, apical plasma membrane, basolateral plasma membrane, clathrin-coated vesicle, early endosome, exocytic vesicle, integral to membrane, lysosome, plasma membrane, protein complex, recycling endosome, rough endoplasmic reticulum, trans-Golgi network, transport vesicle membrane PDZ domain binding, actin binding, glycerol transmembrane transporter activity, transporter activity, water channel activity, water transmembrane transporter activity Human AQP3 BHF-UCL UniProtKB {GO:0005215=PMID:7543093, GO:0007588=PMID:7543093, GO:0005886=Reactome:REACT_23921, GO:0033280=PMID:17943189, GO:0002684=PMID:17943189, GO:0070295=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0015840=GO_REF:0000019, GO:0051592=PMID:17943189, GO:0045616=PMID:17943189, GO:0016323=GO_REF:0000039, GO:0005737=PMID:18718702, GO:0005911=PMID:18718702, GO:0015250=PMID:17943189, GO:0042476=PMID:12522663, GO:0006810=PMID:7543093, GO:0016021=PMID:17943189, GO:0015254=PMID:17943189, GO:0032526=PMID:17943189, GO:0006833=PMID:17943189} Q92482 Aquaporin-3 protein 20080625 {GO:0005215=NAS, GO:0007588=TAS, GO:0005886=TAS, GO:0033280=TAS, GO:0002684=IDA, GO:0070295=IEA, GO:0055085=TAS, GO:0015840=IEA, GO:0051592=TAS, GO:0045616=TAS, GO:0016323=IEA, GO:0005737=IDA, GO:0005911=IDA, GO:0015250=TAS, GO:0042476=IEP, GO:0006810=NAS, GO:0016021=IC, GO:0015254=IDA, GO:0032526=IDA, GO:0006833=TAS} excretion, odontogenesis, positive regulation of immune system process, regulation of keratinocyte differentiation, renal water absorption, response to calcium ion, response to retinoic acid, response to vitamin D, transmembrane transport, transport, urea transport, water transport basolateral plasma membrane, cell-cell junction, cytoplasm, integral to membrane, plasma membrane glycerol channel activity, transporter activity, water channel activity Human AQP4 Reactome UniProtKB {GO:0005215=GO_REF:0000002, GO:0005886=Reactome:REACT_24005, GO:0007605=GO_REF:0000019, GO:0070295=GO_REF:0000019, GO:0016323=GO_REF:0000019, GO:0005737=PMID:18392839, GO:0005911=GO_REF:0000019, GO:0071392=GO_REF:0000019, GO:0015250=Reactome:REACT_24005, GO:0006810=PMID:7559426, GO:0005372=PMID:7559426, GO:0051260=GO_REF:0000019, GO:0006833=Reactome:REACT_24023, GO:0009314=GO_REF:0000019, GO:0007588=PMID:7528931, GO:0007565=GO_REF:0000019, GO:0030315=GO_REF:0000019, GO:0042538=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0015670=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0007399=PMID:7528931, GO:0043234=GO_REF:0000019, GO:0071346=PMID:17645239, GO:0005887=GO_REF:0000019, GO:0050891=PMID:16814974, GO:0015288=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0009897=PMID:17645239} P55087 Aquaporin-4 protein 20090808 {GO:0005215=IEA, GO:0005886=TAS, GO:0007605=IEA, GO:0070295=IEA, GO:0016323=IEA, GO:0005737=IDA, GO:0005911=IEA, GO:0071392=IEA, GO:0015250=EXP, GO:0006810=TAS, GO:0005372=TAS, GO:0051260=IEA, GO:0006833=TAS, GO:0009314=IEA, GO:0007588=TAS, GO:0007565=IEA, GO:0030315=IEA, GO:0042538=IEA, GO:0051384=IEA, GO:0015670=IEA, GO:0055085=TAS, GO:0007399=TAS, GO:0043234=IEA, GO:0071346=IDA, GO:0005887=IEA, GO:0050891=IEP, GO:0015288=IEA, GO:0016021=IEA, GO:0009897=IDA} carbon dioxide transport, cellular response to estradiol stimulus, cellular response to interferon-gamma, excretion, female pregnancy, hyperosmotic salinity response, multicellular organismal water homeostasis, nervous system development, protein homooligomerization, renal water absorption, response to glucocorticoid stimulus, response to radiation, sensory perception of sound, transmembrane transport, transport, water transport T-tubule, basolateral plasma membrane, cell-cell junction, cytoplasm, external side of plasma membrane, integral to membrane, integral to plasma membrane, plasma membrane, protein complex porin activity, transporter activity, water channel activity, water transmembrane transporter activity Human AQP5 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0007588=PMID:8621489, GO:0005886=Reactome:REACT_23858, GO:0005783=GO_REF:0000019, GO:0048593=GO_REF:0000019, GO:0030157=PMID:12801959, GO:0015670=PMID:19273840, GO:0055085=Reactome:REACT_15518, GO:0005902=GO_REF:0000019, GO:0016324=PMID:12801959, GO:0009925=GO_REF:0000019, GO:0005887=PMID:8621489, GO:0015250=PMID:12801959, GO:0042476=PMID:12522663, GO:0006833=Reactome:REACT_23887, GO:0046541=GO_REF:0000019} P55064 Aquaporin-5 protein 20130415 {GO:0005515=IPI, GO:0007588=TAS, GO:0005886=TAS, GO:0005783=IEA, GO:0048593=IEA, GO:0030157=IEP, GO:0015670=IDA, GO:0055085=TAS, GO:0005902=IEA, GO:0016324=IDA, GO:0009925=IEA, GO:0005887=TAS, GO:0015250=IDA, GO:0042476=IEP, GO:0006833=TAS, GO:0046541=IEA} camera-type eye morphogenesis, carbon dioxide transport, excretion, odontogenesis, pancreatic juice secretion, saliva secretion, transmembrane transport, water transport apical plasma membrane, basal plasma membrane, endoplasmic reticulum, integral to plasma membrane, microvillus, plasma membrane protein binding, water channel activity Human UniProtKB:Q99750 AQP9 GOC UniProtKB {GO:0005886=Reactome:REACT_23966, GO:0006863=PMID:9733774, GO:0005275=PMID:9733774, GO:0043231=PMID:18718702, GO:0016323=GO_REF:0000019, GO:0030104=PMID:9733774, GO:0006955=PMID:9514918, GO:0046942=PMID:9733774, GO:0046943=PMID:9733774, GO:0005350=PMID:9733774, GO:0015791=PMID:9733774, GO:0015793=Reactome:REACT_23809, GO:0015250=PMID:9733774, GO:0015837=PMID:9733774, GO:0006810=PMID:9733774, GO:0005372=PMID:9733774, GO:0015254=Reactome:REACT_23966, GO:0006833=Reactome:REACT_23887, GO:0015855=PMID:9733774, GO:0007588=PMID:9733774, GO:0010033=PMID:9733774, GO:0006970=PMID:9733774, GO:0055085=Reactome:REACT_15518, GO:0072531=PMID:9733774, GO:0005887=PMID:9514918, GO:0015166=PMID:9733774, GO:0015722=GO_REF:0000019, GO:0008152=PMID:9733774, GO:0005345=PMID:9733774, GO:0015288=PMID:9733774, GO:0016021=PMID:9733774, GO:0071320=PMID:17636236, GO:0046689=PMID:9733774} O43315 Aquaporin-9 protein 20130413 {GO:0005886=TAS, GO:0006863=IDA, GO:0005275=TAS, GO:0043231=IDA, GO:0016323=IEA, GO:0030104=NAS, GO:0006955=TAS, GO:0046942=TAS, GO:0046943=TAS, GO:0005350=IDA, GO:0015791=IDA, GO:0015793=TAS, GO:0015250=IDA, GO:0015837=IDA, GO:0006810=TAS, GO:0005372=TAS, GO:0015254=EXP, GO:0006833=TAS, GO:0015855=IDA, GO:0007588=TAS, GO:0010033=IDA, GO:0006970=TAS, GO:0055085=TAS, GO:0072531=IDA, GO:0005887=TAS, GO:0015166=TAS, GO:0015722=IEA, GO:0008152=TAS, GO:0005345=IDA, GO:0015288=NAS, GO:0016021=NAS, GO:0071320=IEP, GO:0046689=IDA} amine transport, canalicular bile acid transport, carboxylic acid transport, cellular response to cAMP, excretion, glycerol transport, immune response, metabolic process, polyol transport, purine nucleobase transport, pyrimidine nucleobase transport, pyrimidine-containing compound transmembrane transport, response to mercury ion, response to organic substance, response to osmotic stress, transmembrane transport, transport, water homeostasis, water transport basolateral plasma membrane, integral to membrane, integral to plasma membrane, intracellular membrane-bounded organelle, plasma membrane amine transmembrane transporter activity, carboxylic acid transmembrane transporter activity, glycerol channel activity, polyol transmembrane transporter activity, porin activity, purine nucleobase transmembrane transporter activity, pyrimidine nucleobase transmembrane transporter activity, water channel activity, water transmembrane transporter activity Human AQR UniProtKB UniProtKB {GO:0000398=PMID:11991638, GO:0005681=GO_REF:0000002, GO:0071013=PMID:11991638, GO:0097157=GO_REF:0000002} O60306 Intron-binding protein aquarius protein 20110302 {GO:0000398=IC, GO:0005681=IEA, GO:0071013=IDA, GO:0097157=IEA} mRNA splicing, via spliceosome catalytic step 2 spliceosome, spliceosomal complex pre-mRNA intronic binding Human GO:0071013 AR BHF-UCL UniProtKB {GO:0005515=PMID:18487222, GO:0010467=Reactome:REACT_71, GO:0008219=GO_REF:0000037, GO:0000790=PMID:17505061, GO:0004882=PMID:12799378, GO:0006367=Reactome:REACT_15525, GO:0003700=PMID:11477070, GO:0008013=PMID:12799378, GO:0044212=PMID:18487222, GO:0050680=GO_REF:0000019, GO:0060571=GO_REF:0000019, GO:0050681=GO_REF:0000019, GO:0051259=PMID:18468998, GO:0048645=GO_REF:0000019, GO:0006810=PMID:10835690, GO:0046983=PMID:10075738, GO:0048808=GO_REF:0000019, GO:0007548=PMID:10075738, GO:0004879=PMID:17277772, GO:0005497=PMID:10075738, GO:0005496=GO_REF:0000002, GO:0032868=GO_REF:0000019, GO:0060685=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0003073=GO_REF:0000019, GO:0043234=PMID:18468998, GO:0048638=GO_REF:0000019, GO:0016049=PMID:15572661, GO:0005654=Reactome:REACT_19207, GO:0033148=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0019899=PMID:17277772, GO:0045893=PMID:12799378, GO:0008134=PMID:12799378, GO:0030424=GO_REF:0000019, GO:0008284=PMID:17277772, GO:0060736=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0008283=PMID:10075738, GO:0007267=PMID:10835690, GO:0005634=PMID:19345326, GO:0060599=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0005737=PMID:15572661, GO:0051092=PMID:21310825, GO:0060520=GO_REF:0000019, GO:0045944=PMID:17505061, GO:0001085=PMID:16120611, GO:0045945=PMID:18487222, GO:0030850=PMID:10075738, GO:0060748=GO_REF:0000019, GO:0045720=PMID:21310825, GO:0043066=PMID:21310825, GO:0060742=GO_REF:0000019, GO:0060740=GO_REF:0000019, GO:0005102=PMID:11875111, GO:0045726=PMID:21310825, GO:0003677=PMID:10075738, GO:0070974=GO_REF:0000019, GO:0006351=PMID:15572661, GO:0043565=GO_REF:0000019, GO:0019102=GO_REF:0000019, GO:0007165=PMID:10835690, GO:0050790=GO_REF:0000019, GO:0043568=GO_REF:0000019, GO:0003682=PMID:21730289, GO:0043410=GO_REF:0000019, GO:0030522=PMID:17277772, GO:0090003=PMID:21310825, GO:0030521=PMID:19886863, GO:0008584=GO_REF:0000019, GO:0060749=GO_REF:0000019, GO:0042327=PMID:21310825} P10275 Androgen receptor protein 20120516 {GO:0005515=IPI, GO:0010467=TAS, GO:0008219=IEA, GO:0000790=IDA, GO:0004882=IDA, GO:0006367=TAS, GO:0003700=IDA, GO:0008013=IDA, GO:0044212=IDA, GO:0050680=IEA, GO:0060571=IEA, GO:0050681=IEA, GO:0051259=IDA, GO:0048645=IEA, GO:0006810=TAS, GO:0046983=NAS, GO:0048808=IEA, GO:0007548=NAS, GO:0004879=IDA, GO:0005497=NAS, GO:0005496=IEA, GO:0032868=IEA, GO:0060685=IEA, GO:0001701=IEA, GO:0003073=IEA, GO:0043234=IDA, GO:0048638=IEA, GO:0016049=NAS, GO:0005654=TAS, GO:0033148=IEA, GO:0008270=IEA, GO:0019899=IPI, GO:0045893=IDA, GO:0008134=IPI, GO:0030424=IEA, GO:0008284=IDA, GO:0060736=IEA, GO:0005886=IEA, GO:0008283=NAS, GO:0007267=TAS, GO:0005634=IDA, GO:0060599=IEA, GO:0030425=IEA, GO:0005737=IDA, GO:0051092=IMP, GO:0060520=IEA, GO:0045944=IDA, GO:0001085=IPI, GO:0045945=IDA, GO:0030850=NAS, GO:0060748=IEA, GO:0045720=IDA, GO:0043066=IDA, GO:0060742=IEA, GO:0060740=IEA, GO:0005102=IPI, GO:0045726=IDA, GO:0003677=NAS, GO:0070974=IEA, GO:0006351=IDA, GO:0043565=IEA, GO:0019102=IEA, GO:0007165=TAS, GO:0050790=IEA, GO:0043568=IEA, GO:0003682=IDA, GO:0043410=IEA, GO:0030522=IDA, GO:0090003=IDA, GO:0030521=IDA, GO:0008584=IEA, GO:0060749=IEA, GO:0042327=IMP} activation of prostate induction by androgen receptor signaling pathway, androgen receptor signaling pathway, cell death, cell growth, cell proliferation, cell-cell signaling, epithelial cell differentiation involved in prostate gland development, gene expression, in utero embryonic development, intracellular receptor signaling pathway, lateral sprouting involved in mammary gland duct morphogenesis, male genitalia morphogenesis, male gonad development, male somatic sex determination, mammary gland alveolus development, morphogenesis of an epithelial fold, negative regulation of apoptotic process, negative regulation of epithelial cell proliferation, negative regulation of integrin biosynthetic process, organ formation, positive regulation of MAPK cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of cell proliferation, positive regulation of insulin-like growth factor receptor signaling pathway, positive regulation of integrin biosynthetic process, positive regulation of intracellular estrogen receptor signaling pathway, positive regulation of phosphorylation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase III promoter, positive regulation of transcription, DNA-dependent, prostate gland development, prostate gland epithelium morphogenesis, prostate gland growth, protein oligomerization, regulation of catalytic activity, regulation of developmental growth, regulation of establishment of protein localization to plasma membrane, regulation of prostatic bud formation, regulation of systemic arterial blood pressure, response to insulin stimulus, sex differentiation, signal transduction, tertiary branching involved in mammary gland duct morphogenesis, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transport axon, cytoplasm, dendrite, nuclear chromatin, nucleoplasm, nucleus, plasma membrane, protein complex DNA binding, POU domain binding, RNA polymerase II transcription factor binding, androgen binding, androgen receptor activity, androgen receptor binding, beta-catenin binding, chromatin binding, enzyme binding, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, protein binding, protein dimerization activity, receptor binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid binding, transcription factor binding, transcription regulatory region DNA binding, zinc ion binding Human UniProtKB:O75593 ARAF IntAct UniProtKB {GO:0005515=PMID:22939624, GO:0043066=PMID:19667065, GO:0005575=GO_REF:0000015, GO:0005524=GO_REF:0000029, GO:0046872=GO_REF:0000037, GO:0035556=GO_REF:0000002, GO:0005739=GO_REF:0000019, GO:0033138=PMID:19667065, GO:0004672=PMID:3029685, GO:0016301=GO_REF:0000038, GO:0004674=PMID:19667065, GO:0006468=GO_REF:0000029, GO:0005057=GO_REF:0000002, GO:0006464=PMID:3029685} P10398 Serine/threonine-protein kinase A-Raf protein 20130415 {GO:0005515=IPI, GO:0043066=IDA, GO:0005575=ND, GO:0005524=NAS, GO:0046872=IEA, GO:0035556=IEA, GO:0005739=IEA, GO:0033138=IDA, GO:0004672=TAS, GO:0016301=IEA, GO:0004674=IDA, GO:0006468=NAS, GO:0005057=IEA, GO:0006464=TAS} cellular protein modification process, intracellular signal transduction, negative regulation of apoptotic process, positive regulation of peptidyl-serine phosphorylation, protein phosphorylation cellular_component, mitochondrion ATP binding, kinase activity, metal ion binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, receptor signaling protein activity Human UniProtKB:P08238 ARAP1 IntAct UniProtKB {GO:0005515=PMID:16169070, GO:0051056=Reactome:REACT_11051, GO:0030037=PMID:11804590, GO:0005794=PMID:11804590, GO:0005886=GO_REF:0000039, GO:0007264=Reactome:REACT_11044, GO:0008360=PMID:11804590, GO:0005547=PMID:11804589, GO:0051491=PMID:11804590, GO:0005100=PMID:11804590, GO:0005829=Reactome:REACT_9982, GO:0051497=PMID:11804590, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0008060=PMID:11804590, GO:0005543=GO_REF:0000002, GO:0032312=GO_REF:0000002, GO:0032580=GO_REF:0000039, GO:0043089=PMID:11804590, GO:0008270=GO_REF:0000002, GO:0005096=GO_REF:0000038, GO:0051270=PMID:11804590} Q96P48 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 protein 20130415 {GO:0005515=IPI, GO:0051056=TAS, GO:0030037=TAS, GO:0005794=IDA, GO:0005886=IEA, GO:0007264=TAS, GO:0008360=IMP, GO:0005547=IDA, GO:0051491=IMP, GO:0005100=IDA, GO:0005829=TAS, GO:0051497=IMP, GO:0005622=IEA, GO:0007165=IEA, GO:0008060=IDA, GO:0005543=IEA, GO:0032312=IEA, GO:0032580=IEA, GO:0043089=IDA, GO:0008270=IEA, GO:0005096=IEA, GO:0051270=IMP} actin filament reorganization involved in cell cycle, negative regulation of stress fiber assembly, positive regulation of Cdc42 GTPase activity, positive regulation of filopodium assembly, regulation of ARF GTPase activity, regulation of cell shape, regulation of cellular component movement, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction Golgi apparatus, Golgi cisterna membrane, cytosol, intracellular, plasma membrane ARF GTPase activator activity, GTPase activator activity, Rho GTPase activator activity, phosphatidylinositol-3,4,5-trisphosphate binding, phospholipid binding, protein binding, zinc ion binding Human UniProtKB:P12956 ARAP2 Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0008060=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0032312=GO_REF:0000002, GO:0005547=PMID:11804589, GO:0008270=GO_REF:0000002, GO:0005829=Reactome:REACT_9982} Q8WZ64 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 protein 20130301 {GO:0051056=TAS, GO:0008060=IEA, GO:0007264=TAS, GO:0032312=IEA, GO:0005547=IDA, GO:0008270=IEA, GO:0005829=TAS} regulation of ARF GTPase activity, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol ARF GTPase activator activity, phosphatidylinositol-3,4,5-trisphosphate binding, zinc ion binding Human ARAP3 Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0030336=GO_REF:0000024, GO:0035021=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0007264=Reactome:REACT_11044, GO:0043325=PMID:11804589, GO:0008360=GO_REF:0000024, GO:0035024=GO_REF:0000024, GO:0005547=PMID:11804589, GO:0001726=GO_REF:0000024, GO:0005100=GO_REF:0000024, GO:0030027=GO_REF:0000024, GO:0005829=Reactome:REACT_9982, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0008060=GO_REF:0000024, GO:0005737=PMID:11804589, GO:0005543=GO_REF:0000002, GO:0032312=GO_REF:0000002, GO:0007010=PMID:15569923, GO:0008270=GO_REF:0000002, GO:0016192=PMID:15569923, GO:0005856=GO_REF:0000039, GO:0030675=GO_REF:0000024} Q8WWN8 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 protein 20130301 {GO:0051056=TAS, GO:0030336=ISS, GO:0035021=IEA, GO:0005886=IEA, GO:0007264=TAS, GO:0043325=IDA, GO:0008360=ISS, GO:0035024=ISS, GO:0005547=IDA, GO:0001726=ISS, GO:0005100=ISS, GO:0030027=ISS, GO:0005829=TAS, GO:0005622=IEA, GO:0007165=IEA, GO:0008060=ISS, GO:0005737=IC, GO:0005543=IEA, GO:0032312=IEA, GO:0007010=TAS, GO:0008270=IEA, GO:0016192=TAS, GO:0005856=IEA, GO:0030675=ISS} cytoskeleton organization, negative regulation of Rac protein signal transduction, negative regulation of Rho protein signal transduction, negative regulation of cell migration, regulation of ARF GTPase activity, regulation of cell shape, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction, vesicle-mediated transport cytoplasm, cytoskeleton, cytosol, intracellular, lamellipodium, plasma membrane, ruffle ARF GTPase activator activity, Rac GTPase activator activity, Rho GTPase activator activity, phosphatidylinositol-3,4,5-trisphosphate binding, phosphatidylinositol-3,4-bisphosphate binding, phospholipid binding, zinc ion binding Human ARC UniProtKB UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=PMID:21834987, GO:0001669=GO_REF:0000039, GO:0014069=GO_REF:0000039, GO:0009952=GO_REF:0000019, GO:0015629=GO_REF:0000019, GO:0006897=GO_REF:0000037, GO:0005737=PMID:21834987, GO:0007492=GO_REF:0000019, GO:0048168=GO_REF:0000019, GO:0016477=PMID:21834987, GO:0045211=GO_REF:0000037, GO:0022604=PMID:21834987, GO:0007010=PMID:21834987, GO:0007612=GO_REF:0000019, GO:0005768=GO_REF:0000039} Q7LC44 Activity-regulated cytoskeleton-associated protein protein 20110926 {GO:0030054=IEA, GO:0005886=IDA, GO:0001669=IEA, GO:0014069=IEA, GO:0009952=IEA, GO:0015629=IEA, GO:0006897=IEA, GO:0005737=IDA, GO:0007492=IEA, GO:0048168=IEA, GO:0016477=IMP, GO:0045211=IEA, GO:0022604=IMP, GO:0007010=IMP, GO:0007612=IEA, GO:0005768=IEA} anterior/posterior pattern specification, cell migration, cytoskeleton organization, endocytosis, endoderm development, learning, regulation of cell morphogenesis, regulation of neuronal synaptic plasticity acrosomal vesicle, actin cytoskeleton, cell junction, cytoplasm, endosome, plasma membrane, postsynaptic density, postsynaptic membrane Human ARCN1 Reactome UniProtKB {GO:0030131=GO_REF:0000002, GO:0030126=GO_REF:0000024, GO:0006890=Reactome:REACT_11208, GO:0006886=GO_REF:0000002, GO:0048205=Reactome:REACT_11096, GO:0016044=Reactome:REACT_11123, GO:0005829=Reactome:REACT_11243} P48444 Coatomer subunit delta protein 20130213 {GO:0030131=IEA, GO:0030126=ISS, GO:0006890=TAS, GO:0006886=IEA, GO:0048205=TAS, GO:0016044=TAS, GO:0005829=TAS} COPI coating of Golgi vesicle, cellular membrane organization, intracellular protein transport, retrograde vesicle-mediated transport, Golgi to ER COPI vesicle coat, clathrin adaptor complex, cytosol Human AREG BHF-UCL UniProtKB {GO:0009986=PMID:12743035, GO:0007186=PMID:12743035, GO:0007173=PMID:12743035, GO:0008283=PMID:2466334, GO:0045740=PMID:12743035, GO:0007267=PMID:2466334, GO:0016021=GO_REF:0000037, GO:0005615=PMID:12743035, GO:0008083=GO_REF:0000037, GO:0005125=GO_REF:0000037} P15514 Amphiregulin protein 20081121 {GO:0009986=IDA, GO:0007186=IDA, GO:0007173=IDA, GO:0008283=TAS, GO:0045740=IMP, GO:0007267=TAS, GO:0016021=IEA, GO:0005615=IDA, GO:0008083=IEA, GO:0005125=IEA} G-protein coupled receptor signaling pathway, cell proliferation, cell-cell signaling, epidermal growth factor receptor signaling pathway, positive regulation of DNA replication cell surface, extracellular space, integral to membrane cytokine activity, growth factor activity Human ARF1 GOC UniProtKB {GO:0005515=PMID:14654833, GO:0048471=GO_REF:0000039, GO:0005886=PMID:8529647, GO:0006661=Reactome:REACT_120836, GO:0007264=GO_REF:0000002, GO:0006890=Reactome:REACT_11208, GO:0006892=Reactome:REACT_11235, GO:0003924=PMID:1577740, GO:0044281=Reactome:REACT_111217, GO:0005525=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0030017=GO_REF:0000019, GO:0048205=Reactome:REACT_11096, GO:0050690=Reactome:REACT_11166, GO:0005829=Reactome:REACT_121003, GO:0006184=PMID:1577740, GO:0019886=Reactome:REACT_121399, GO:0006878=PMID:21034850, GO:0000139=Reactome:REACT_121296, GO:0016032=Reactome:REACT_6185, GO:0005057=PMID:8529647, GO:0006644=Reactome:REACT_121175, GO:0016044=Reactome:REACT_11123} P84077 ADP-ribosylation factor 1 protein 20130413 {GO:0005515=IPI, GO:0048471=IEA, GO:0005886=TAS, GO:0006661=TAS, GO:0007264=IEA, GO:0006890=TAS, GO:0006892=TAS, GO:0003924=TAS, GO:0044281=TAS, GO:0005525=IEA, GO:0015031=IEA, GO:0030017=IEA, GO:0048205=TAS, GO:0050690=TAS, GO:0005829=TAS, GO:0006184=TAS, GO:0019886=TAS, GO:0006878=IMP, GO:0000139=TAS, GO:0016032=TAS, GO:0005057=TAS, GO:0006644=TAS, GO:0016044=TAS} COPI coating of Golgi vesicle, GTP catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class II, cellular copper ion homeostasis, cellular membrane organization, phosphatidylinositol biosynthetic process, phospholipid metabolic process, post-Golgi vesicle-mediated transport, protein transport, regulation of defense response to virus by virus, retrograde vesicle-mediated transport, Golgi to ER, small GTPase mediated signal transduction, small molecule metabolic process, viral reproduction Golgi membrane, cytosol, perinuclear region of cytoplasm, plasma membrane, sarcomere GTP binding, GTPase activity, protein binding, receptor signaling protein activity Human ARF3 GOC UniProtKB {GO:0048471=GO_REF:0000039, GO:0005794=GO_REF:0000019, GO:0006661=Reactome:REACT_120836, GO:0007264=GO_REF:0000002, GO:0003924=PMID:1744102, GO:0044281=Reactome:REACT_111217, GO:0005525=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0005622=GO_REF:0000002, GO:0006184=PMID:1744102, GO:0000139=Reactome:REACT_121296, GO:0016192=GO_REF:0000037, GO:0006644=Reactome:REACT_121175} P61204 ADP-ribosylation factor 3 protein 20130413 {GO:0048471=IEA, GO:0005794=IEA, GO:0006661=TAS, GO:0007264=IEA, GO:0003924=TAS, GO:0044281=TAS, GO:0005525=IEA, GO:0015031=IEA, GO:0005622=IEA, GO:0006184=TAS, GO:0000139=TAS, GO:0016192=IEA, GO:0006644=TAS} GTP catabolic process, phosphatidylinositol biosynthetic process, phospholipid metabolic process, protein transport, small GTPase mediated signal transduction, small molecule metabolic process, vesicle-mediated transport Golgi apparatus, Golgi membrane, intracellular, perinuclear region of cytoplasm GTP binding, GTPase activity Human ARF4 GOC UniProtKB {GO:0005515=PMID:21988832, GO:0005794=GO_REF:0000039, GO:0005886=GO_REF:0000019, GO:0007264=GO_REF:0000002, GO:0003924=PMID:2107548, GO:0005525=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0048678=GO_REF:0000019, GO:0006184=PMID:2107548, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000019, GO:0007173=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0016192=GO_REF:0000037} P18085 ADP-ribosylation factor 4 protein 20130413 {GO:0005515=IPI, GO:0005794=IEA, GO:0005886=IEA, GO:0007264=IEA, GO:0003924=TAS, GO:0005525=IEA, GO:0015031=IEA, GO:0048678=IEA, GO:0006184=TAS, GO:0005622=IEA, GO:0005737=IEA, GO:0007173=IEA, GO:0007420=IEA, GO:0016192=IEA} GTP catabolic process, brain development, epidermal growth factor receptor signaling pathway, protein transport, response to axon injury, small GTPase mediated signal transduction, vesicle-mediated transport Golgi apparatus, cytoplasm, intracellular, plasma membrane GTP binding, GTPase activity, protein binding Human ARF5 GOC UniProtKB {GO:0006184=PMID:1993656, GO:0005515=PMID:17030804, GO:0005622=GO_REF:0000002, GO:0048471=GO_REF:0000039, GO:0005794=GO_REF:0000039, GO:0005886=GO_REF:0000019, GO:0007264=GO_REF:0000002, GO:0003924=PMID:1993656, GO:0016192=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0005525=GO_REF:0000037} P84085 ADP-ribosylation factor 5 protein 20130413 {GO:0006184=TAS, GO:0005515=IPI, GO:0005622=IEA, GO:0048471=IEA, GO:0005794=IEA, GO:0005886=IEA, GO:0007264=IEA, GO:0003924=TAS, GO:0016192=IEA, GO:0015031=IEA, GO:0005525=IEA} GTP catabolic process, protein transport, small GTPase mediated signal transduction, vesicle-mediated transport Golgi apparatus, intracellular, perinuclear region of cytoplasm, plasma membrane GTP binding, GTPase activity, protein binding Human ARF6 GOC UniProtKB {GO:0090162=GO_REF:0000019, GO:0005515=PMID:16415858, GO:0035020=PMID:10036235, GO:0005886=PMID:19948740, GO:0007264=GO_REF:0000002, GO:0003924=PMID:1993656, GO:0031527=PMID:14978216, GO:0006928=PMID:10036235, GO:0030139=PMID:19948740, GO:0031996=PMID:15509780, GO:0015031=GO_REF:0000037, GO:0031529=PMID:10036235, GO:0051489=PMID:14978216, GO:0030838=PMID:10036235, GO:0016192=PMID:10913182, GO:0007155=PMID:10036235, GO:0060998=GO_REF:0000024, GO:0005938=PMID:10913182, GO:0005794=GO_REF:0000039, GO:0006915=GO_REF:0000019, GO:0005525=PMID:10913182, GO:0001726=PMID:9312003, GO:0006184=PMID:1993656, GO:0001889=GO_REF:0000019, GO:0016020=PMID:8702973, GO:0030866=PMID:10913182, GO:0034394=GO_REF:0000024, GO:0048261=PMID:9312003, GO:0055037=GO_REF:0000019, GO:0010008=GO_REF:0000039, GO:0005769=GO_REF:0000019, GO:0090004=GO_REF:0000024, GO:0005768=PMID:20682791} P62330 ADP-ribosylation factor 6 protein 20130413 {GO:0090162=IEA, GO:0005515=IPI, GO:0035020=IDA, GO:0005886=IDA, GO:0007264=IEA, GO:0003924=TAS, GO:0031527=IDA, GO:0006928=TAS, GO:0030139=IDA, GO:0031996=IPI, GO:0015031=IEA, GO:0031529=IDA, GO:0051489=IDA, GO:0030838=IMP, GO:0016192=TAS, GO:0007155=TAS, GO:0060998=ISS, GO:0005938=IDA, GO:0005794=IEA, GO:0006915=IEA, GO:0005525=TAS, GO:0001726=IDA, GO:0006184=TAS, GO:0001889=IEA, GO:0016020=TAS, GO:0030866=IMP, GO:0034394=ISS, GO:0048261=TAS, GO:0055037=IEA, GO:0010008=IEA, GO:0005769=IEA, GO:0090004=ISS, GO:0005768=IDA} GTP catabolic process, apoptotic process, cell adhesion, cellular component movement, cortical actin cytoskeleton organization, establishment of epithelial cell polarity, liver development, negative regulation of receptor-mediated endocytosis, positive regulation of actin filament polymerization, positive regulation of establishment of protein localization to plasma membrane, protein localization to cell surface, protein transport, regulation of Rac protein signal transduction, regulation of dendritic spine development, regulation of filopodium assembly, ruffle organization, small GTPase mediated signal transduction, vesicle-mediated transport Golgi apparatus, cell cortex, early endosome, endocytic vesicle, endosome, endosome membrane, filopodium membrane, membrane, plasma membrane, recycling endosome, ruffle GTP binding, GTPase activity, protein binding, thioesterase binding Human ARFGAP1 HPA UniProtKB {GO:0031965=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005783=GO_REF:0000052, GO:0006890=Reactome:REACT_11208, GO:0045202=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0048205=Reactome:REACT_11096, GO:0030968=Reactome:REACT_18356, GO:0043231=GO_REF:0000052, GO:0005829=Reactome:REACT_115613, GO:0043547=PMID:22423108, GO:0008060=GO_REF:0000002, GO:0000139=GO_REF:0000019, GO:0032312=GO_REF:0000002, GO:0030660=Reactome:REACT_11138, GO:0008270=GO_REF:0000002, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0016044=Reactome:REACT_11123, GO:0005096=PMID:22423108} Q8N6T3 ADP-ribosylation factor GTPase-activating protein 1 protein 20120912 {GO:0031965=IDA, GO:0005886=IDA, GO:0005783=IDA, GO:0006890=TAS, GO:0045202=IEA, GO:0015031=IEA, GO:0048205=TAS, GO:0030968=TAS, GO:0043231=IDA, GO:0005829=TAS, GO:0043547=IDA, GO:0008060=IEA, GO:0000139=IEA, GO:0032312=IEA, GO:0030660=TAS, GO:0008270=IEA, GO:0006987=TAS, GO:0044267=TAS, GO:0016044=TAS, GO:0005096=IDA} COPI coating of Golgi vesicle, activation of signaling protein activity involved in unfolded protein response, cellular membrane organization, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, positive regulation of GTPase activity, protein transport, regulation of ARF GTPase activity, retrograde vesicle-mediated transport, Golgi to ER Golgi membrane, Golgi-associated vesicle membrane, cytosol, endoplasmic reticulum, intracellular membrane-bounded organelle, nuclear membrane, plasma membrane, synapse ARF GTPase activator activity, GTPase activator activity, zinc ion binding Human ARFGAP2 HPA UniProtKB {GO:0008060=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0000139=GO_REF:0000039, GO:0005886=GO_REF:0000052, GO:0032312=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0016192=GO_REF:0000037, GO:0015031=GO_REF:0000037} Q8N6H7 ADP-ribosylation factor GTPase-activating protein 2 protein 20101115 {GO:0008060=IEA, GO:0005737=IDA, GO:0005794=IDA, GO:0000139=IEA, GO:0005886=IDA, GO:0032312=IEA, GO:0005730=IDA, GO:0008270=IEA, GO:0016192=IEA, GO:0015031=IEA} protein transport, regulation of ARF GTPase activity, vesicle-mediated transport Golgi apparatus, Golgi membrane, cytoplasm, nucleolus, plasma membrane ARF GTPase activator activity, zinc ion binding Human ARFGAP3 HPA UniProtKB {GO:0008060=PMID:11172815, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0009306=PMID:11172815, GO:0000139=GO_REF:0000039, GO:0032312=GO_REF:0000002, GO:0008565=PMID:11172815, GO:0008270=GO_REF:0000002, GO:0016192=PMID:11172815, GO:0006886=PMID:11172815, GO:0005829=PMID:11172815} Q9NP61 ADP-ribosylation factor GTPase-activating protein 3 protein 20101115 {GO:0008060=IDA, GO:0005737=IDA, GO:0005794=IDA, GO:0009306=IEP, GO:0000139=IEA, GO:0032312=IEA, GO:0008565=NAS, GO:0008270=IEA, GO:0016192=NAS, GO:0006886=NAS, GO:0005829=IDA} intracellular protein transport, protein secretion, regulation of ARF GTPase activity, vesicle-mediated transport Golgi apparatus, Golgi membrane, cytoplasm, cytosol ARF GTPase activator activity, protein transporter activity, zinc ion binding Human ARFGEF1 HPA UniProtKB {GO:0005515=PMID:19020088, GO:0005802=GO_REF:0000024, GO:0034237=PMID:12571360, GO:0048471=PMID:22084092, GO:0034259=PMID:15644318, GO:0090303=PMID:22084092, GO:0090284=PMID:17227842, GO:0005634=GO_REF:0000052, GO:0015031=GO_REF:0000037, GO:0006887=PMID:10212200, GO:0010256=PMID:20360857, GO:0016363=GO_REF:0000039, GO:0005829=PMID:10716990, GO:0005085=PMID:15644318, GO:0005086=GO_REF:0000033, GO:0005737=GO_REF:0000052, GO:0030837=PMID:22084092, GO:0007030=PMID:20360857, GO:0030532=PMID:18292223, GO:0016192=GO_REF:0000033, GO:0005794=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:2000114=PMID:22084092, GO:0008060=PMID:15644318, GO:0000139=PMID:10716990, GO:0032012=GO_REF:0000002, GO:0017022=PMID:15644318} Q9Y6D6 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 protein 20100326 {GO:0005515=IPI, GO:0005802=ISS, GO:0034237=IDA, GO:0048471=IDA, GO:0034259=IDA, GO:0090303=IMP, GO:0090284=IMP, GO:0005634=IDA, GO:0015031=IEA, GO:0006887=TAS, GO:0010256=IMP, GO:0016363=IEA, GO:0005829=IDA, GO:0005085=IDA, GO:0005086=IBA, GO:0005737=IDA, GO:0030837=IMP, GO:0007030=IMP, GO:0030532=IDA, GO:0016192=IBA, GO:0005794=IDA, GO:0005730=IDA, GO:2000114=IMP, GO:0008060=IDA, GO:0000139=IDA, GO:0032012=IEA, GO:0017022=IPI} Golgi organization, endomembrane system organization, exocytosis, negative regulation of Rho GTPase activity, negative regulation of actin filament polymerization, positive regulation of protein glycosylation in Golgi, positive regulation of wound healing, protein transport, regulation of ARF protein signal transduction, regulation of establishment of cell polarity, vesicle-mediated transport Golgi apparatus, Golgi membrane, cytoplasm, cytosol, nuclear matrix, nucleolus, nucleus, perinuclear region of cytoplasm, small nuclear ribonucleoprotein complex, trans-Golgi network ARF GTPase activator activity, ARF guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, myosin binding, protein binding, protein kinase A regulatory subunit binding Human ARFGEF2 IntAct UniProtKB {GO:0005515=PMID:15705715, GO:0005802=GO_REF:0000024, GO:0034237=PMID:12571360, GO:0048471=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0050811=GO_REF:0000024, GO:0006887=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0010256=PMID:20360857, GO:0005829=PMID:12571360, GO:0032279=GO_REF:0000024, GO:0035556=PMID:12571360, GO:0005085=PMID:10212200, GO:0005086=PMID:15385626, GO:0001881=PMID:16477018, GO:0032280=GO_REF:0000024, GO:0043197=GO_REF:0000024, GO:0005879=GO_REF:0000024, GO:0007032=PMID:20360857, GO:0016192=GO_REF:0000033, GO:0005815=PMID:15705715, GO:0032760=PMID:17276987, GO:0006893=PMID:17276987, GO:0031410=GO_REF:0000024, GO:0016020=PMID:12571360, GO:0000139=PMID:12571360, GO:0016023=GO_REF:0000039, GO:0032012=GO_REF:0000002, GO:0017022=GO_REF:0000019, GO:0055037=PMID:15385626} Q9Y6D5 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 protein 20130415 {GO:0005515=IPI, GO:0005802=ISS, GO:0034237=IDA, GO:0048471=IEA, GO:0030054=IEA, GO:0050811=ISS, GO:0006887=IEA, GO:0015031=IEA, GO:0010256=IMP, GO:0005829=IDA, GO:0032279=ISS, GO:0035556=IDA, GO:0005085=IDA, GO:0005086=IDA, GO:0001881=IDA, GO:0032280=ISS, GO:0043197=ISS, GO:0005879=ISS, GO:0007032=IMP, GO:0016192=IBA, GO:0005815=IDA, GO:0032760=IMP, GO:0006893=IMP, GO:0031410=ISS, GO:0016020=IDA, GO:0000139=IDA, GO:0016023=IEA, GO:0032012=IEA, GO:0017022=IEA, GO:0055037=IDA} Golgi to plasma membrane transport, endomembrane system organization, endosome organization, exocytosis, intracellular signal transduction, positive regulation of tumor necrosis factor production, protein transport, receptor recycling, regulation of ARF protein signal transduction, vesicle-mediated transport Golgi membrane, asymmetric synapse, axonemal microtubule, cell junction, cytoplasmic membrane-bounded vesicle, cytoplasmic vesicle, cytosol, dendritic spine, membrane, microtubule organizing center, perinuclear region of cytoplasm, recycling endosome, symmetric synapse, trans-Golgi network ARF guanyl-nucleotide exchange factor activity, GABA receptor binding, guanyl-nucleotide exchange factor activity, myosin binding, protein binding, protein kinase A regulatory subunit binding Human UniProtKB:Q9UPT5-1 ARFIP1 MGI UniProtKB {GO:0003674=GO_REF:0000015, GO:0000139=PMID:9038142, GO:0019904=GO_REF:0000002, GO:0050708=PMID:12606037, GO:0006886=PMID:12606037, GO:0005829=PMID:9038142, GO:0042802=GO_REF:0000019} P53367 Arfaptin-1 protein 20060110 {GO:0003674=ND, GO:0000139=IDA, GO:0019904=IEA, GO:0050708=IDA, GO:0006886=IDA, GO:0005829=IDA, GO:0042802=IEA} intracellular protein transport, regulation of protein secretion Golgi membrane, cytosol identical protein binding, molecular_function, protein domain specific binding Human ARFIP2 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0030036=PMID:9312003, GO:0005886=PMID:9312003, GO:0007264=PMID:8670882, GO:0019904=GO_REF:0000002, GO:0030032=PMID:9312003, GO:0006928=PMID:8670882, GO:0005525=PMID:8670882, GO:0001726=PMID:8670882, GO:0031529=PMID:9312003, GO:0048365=PMID:9312003, GO:0030742=PMID:9312003, GO:0005737=PMID:9312003, GO:0005938=PMID:9312003} P53365 Arfaptin-2 protein 20130415 {GO:0005515=IPI, GO:0030036=IMP, GO:0005886=TAS, GO:0007264=TAS, GO:0019904=IEA, GO:0030032=TAS, GO:0006928=TAS, GO:0005525=TAS, GO:0001726=IMP, GO:0031529=TAS, GO:0048365=TAS, GO:0030742=IPI, GO:0005737=TAS, GO:0005938=IDA} actin cytoskeleton organization, cellular component movement, lamellipodium assembly, ruffle organization, small GTPase mediated signal transduction cell cortex, cytoplasm, plasma membrane, ruffle GTP binding, GTP-dependent protein binding, Rac GTPase binding, protein binding, protein domain specific binding Human UniProtKB:P63000 ARFRP1 GOC UniProtKB {GO:0005802=PMID:16129887, GO:0005515=PMID:11438518, GO:0007369=GO_REF:0000019, GO:0005794=PMID:19224922, GO:0007264=GO_REF:0000002, GO:0043001=PMID:16129887, GO:0003924=PMID:8530503, GO:0005525=GO_REF:0000037, GO:0006184=PMID:8530503, GO:0007165=PMID:8530503, GO:0016020=GO_REF:0000019, GO:0034067=PMID:19224922, GO:0042147=PMID:16129887} Q13795 ADP-ribosylation factor-related protein 1 protein 20130413 {GO:0005802=IDA, GO:0005515=IPI, GO:0007369=IEA, GO:0005794=IDA, GO:0007264=IEA, GO:0043001=IMP, GO:0003924=TAS, GO:0005525=IEA, GO:0006184=TAS, GO:0007165=TAS, GO:0016020=IEA, GO:0034067=IMP, GO:0042147=IMP} GTP catabolic process, Golgi to plasma membrane protein transport, gastrulation, protein localization to Golgi apparatus, retrograde transport, endosome to Golgi, signal transduction, small GTPase mediated signal transduction Golgi apparatus, membrane, trans-Golgi network GTP binding, GTPase activity, protein binding Human ARG1 Reactome UniProtKB {GO:0043005=GO_REF:0000019, GO:0070301=GO_REF:0000019, GO:0030324=GO_REF:0000019, GO:0033189=GO_REF:0000019, GO:0071560=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0014075=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0048678=GO_REF:0000019, GO:0010043=GO_REF:0000019, GO:0010042=GO_REF:0000019, GO:0005829=Reactome:REACT_394, GO:0034641=Reactome:REACT_13, GO:0070207=GO_REF:0000019, GO:0005737=PMID:3540966, GO:0010963=GO_REF:0000019, GO:0071377=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0033197=GO_REF:0000019, GO:0006527=PMID:3540966, GO:0043200=GO_REF:0000019, GO:0030145=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0060056=GO_REF:0000019, GO:0060135=GO_REF:0000019, GO:0010269=GO_REF:0000019, GO:0009635=GO_REF:0000019, GO:0001889=GO_REF:0000019, GO:0071222=GO_REF:0000019, GO:0001938=GO_REF:0000019, GO:0051597=GO_REF:0000019, GO:0000050=Reactome:REACT_847, GO:0032964=GO_REF:0000019, GO:0004053=Reactome:REACT_394, GO:0046686=GO_REF:0000019, GO:0071549=GO_REF:0000019} P05089 Arginase-1 protein 20130213 {GO:0043005=IEA, GO:0070301=IEA, GO:0030324=IEA, GO:0033189=IEA, GO:0071560=IEA, GO:0044281=TAS, GO:0014075=IEA, GO:0005615=IEA, GO:0048678=IEA, GO:0010043=IEA, GO:0010042=IEA, GO:0005829=TAS, GO:0034641=TAS, GO:0070207=IEA, GO:0005737=TAS, GO:0010963=IEA, GO:0071377=IEA, GO:0043025=IEA, GO:0033197=IEA, GO:0006527=TAS, GO:0043200=IEA, GO:0030145=IEA, GO:0042493=IEA, GO:0060056=IEA, GO:0060135=IEA, GO:0010269=IEA, GO:0009635=IEA, GO:0001889=IEA, GO:0071222=IEA, GO:0001938=IEA, GO:0051597=IEA, GO:0000050=TAS, GO:0032964=IEA, GO:0004053=EXP, GO:0046686=IEA, GO:0071549=IEA} arginine catabolic process, cellular nitrogen compound metabolic process, cellular response to dexamethasone stimulus, cellular response to glucagon stimulus, cellular response to hydrogen peroxide, cellular response to lipopolysaccharide, cellular response to transforming growth factor beta stimulus, collagen biosynthetic process, liver development, lung development, mammary gland involution, maternal process involved in female pregnancy, positive regulation of endothelial cell proliferation, protein homotrimerization, regulation of L-arginine import, response to amine stimulus, response to amino acid stimulus, response to axon injury, response to cadmium ion, response to drug, response to herbicide, response to manganese ion, response to methylmercury, response to selenium ion, response to vitamin A, response to vitamin E, response to zinc ion, small molecule metabolic process, urea cycle cytoplasm, cytosol, extracellular space, neuron projection, neuronal cell body arginase activity, manganese ion binding Human ARG2 Reactome UniProtKB {GO:0005739=PMID:8898077, GO:0034641=Reactome:REACT_13, GO:0001657=GO_REF:0000019, GO:0005759=Reactome:REACT_21325, GO:0000050=Reactome:REACT_847, GO:0006941=GO_REF:0000019, GO:0006525=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0004053=Reactome:REACT_21325, GO:0046872=GO_REF:0000037, GO:0006809=PMID:8898077} P78540 Arginase-2, mitochondrial protein 20130213 {GO:0005739=TAS, GO:0034641=TAS, GO:0001657=IEA, GO:0005759=TAS, GO:0000050=TAS, GO:0006941=IEA, GO:0006525=IEA, GO:0044281=TAS, GO:0004053=EXP, GO:0046872=IEA, GO:0006809=TAS} arginine metabolic process, cellular nitrogen compound metabolic process, nitric oxide biosynthetic process, small molecule metabolic process, striated muscle contraction, urea cycle, ureteric bud development mitochondrial matrix, mitochondrion arginase activity, metal ion binding Human ARGLU1 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q9NWB6 Arginine and glutamate-rich protein 1 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus Human UniProtKB-SubCell:SL-0191 ARHGAP1 HPA UniProtKB {GO:0005515=PMID:16189514, GO:0051056=Reactome:REACT_11051, GO:0017124=GO_REF:0000037, GO:0005886=GO_REF:0000019, GO:0007264=Reactome:REACT_11044, GO:0007266=PMID:8253717, GO:0001726=GO_REF:0000019, GO:0005100=PMID:8288572, GO:0043231=GO_REF:0000052, GO:0005829=Reactome:REACT_9982, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0005070=PMID:8253717, GO:0030675=GO_REF:0000019} Q07960 Rho GTPase-activating protein 1 protein 20101115 {GO:0005515=IPI, GO:0051056=TAS, GO:0017124=IEA, GO:0005886=IEA, GO:0007264=TAS, GO:0007266=TAS, GO:0001726=IEA, GO:0005100=IDA, GO:0043231=IDA, GO:0005829=TAS, GO:0005622=IEA, GO:0007165=IEA, GO:0005070=TAS, GO:0030675=IEA} Rho protein signal transduction, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular, intracellular membrane-bounded organelle, plasma membrane, ruffle Rac GTPase activator activity, Rho GTPase activator activity, SH3 domain binding, SH3/SH2 adaptor activity, protein binding Human ARHGAP10 UniProtKB UniProtKB {GO:0005515=PMID:11432776, GO:0051056=Reactome:REACT_11051, GO:0043066=GO_REF:0000019, GO:0048471=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0007264=Reactome:REACT_11044, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0005100=GO_REF:0000019, GO:0005829=Reactome:REACT_9982, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0007010=GO_REF:0000019, GO:0005096=GO_REF:0000038} H0Y8W5 Rho GTPase-activating protein 10 protein 20130413 {GO:0005515=IPI, GO:0051056=TAS, GO:0043066=IEA, GO:0048471=IEA, GO:0005886=IEA, GO:0007264=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0005100=IEA, GO:0005829=TAS, GO:0005622=IEA, GO:0007165=IEA, GO:0005543=IEA, GO:0007010=IEA, GO:0005096=IEA} apoptotic process, cytoskeleton organization, negative regulation of apoptotic process, regulation of apoptotic process, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular, perinuclear region of cytoplasm, plasma membrane GTPase activator activity, Rho GTPase activator activity, phospholipid binding, protein binding Human UniProtKB-KW:KW-0343 ARHGAP11A Reactome UniProtKB {GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} Q6P4F7 Rho GTPase-activating protein 11A protein 20130301 {GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0007264=TAS, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular GTPase activator activity Human ARHGAP11B Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0007264=Reactome:REACT_11044, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} Q3KRB8 Rho GTPase-activating protein 11B protein 20130301 {GO:0051056=TAS, GO:0007264=TAS, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol GTPase activator activity Human ARHGAP12 Reactome UniProtKB {GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} Q8IWW6 Rho GTPase-activating protein 12 protein 20130301 {GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0005543=IEA, GO:0007264=TAS, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular GTPase activator activity, phospholipid binding Human ARHGAP15 GOC UniProtKB {GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0007264=Reactome:REACT_11044, GO:0008360=PMID:12650940, GO:0032855=PMID:12650940, GO:0030675=PMID:12650940, GO:0005829=Reactome:REACT_9982} Q53QZ3 Rho GTPase-activating protein 15 protein 20130413 {GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0005543=IEA, GO:0016020=IEA, GO:0007264=TAS, GO:0008360=IDA, GO:0032855=IDA, GO:0030675=IDA, GO:0005829=TAS} positive regulation of Rac GTPase activity, regulation of cell shape, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular, membrane Rac GTPase activator activity, phospholipid binding Human ARHGAP17 IntAct UniProtKB {GO:0005515=PMID:21481793, GO:0051056=Reactome:REACT_11051, GO:0017124=GO_REF:0000037, GO:0005737=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0007264=Reactome:REACT_11044, GO:0005923=GO_REF:0000039, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} Q68EM7 Rho GTPase-activating protein 17 protein 20130415 {GO:0005515=IPI, GO:0051056=TAS, GO:0017124=IEA, GO:0005737=IEA, GO:0016020=IEA, GO:0007264=TAS, GO:0005923=IEA, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytoplasm, cytosol, membrane, tight junction GTPase activator activity, SH3 domain binding, protein binding Human UniProtKB:Q4VCS5-2 ARHGAP18 Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0007264=Reactome:REACT_11044, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} Q8N392 Rho GTPase-activating protein 18 protein 20130301 {GO:0051056=TAS, GO:0007264=TAS, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol GTPase activator activity Human ARHGAP19 Reactome UniProtKB {GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0005634=GO_REF:0000039, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} Q14CB8 Rho GTPase-activating protein 19 protein 20130301 {GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0007264=TAS, GO:0005634=IEA, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular, nucleus GTPase activator activity Human ARHGAP20 Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0005543=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} Q9P2F6 Rho GTPase-activating protein 20 protein 20130301 {GO:0051056=TAS, GO:0005543=IEA, GO:0007264=TAS, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol GTPase activator activity, phospholipid binding Human ARHGAP21 BHF-UCL UniProtKB {GO:0005515=PMID:20195357, GO:0030054=GO_REF:0000039, GO:0005794=PMID:20525016, GO:0072384=PMID:20525016, GO:0051684=PMID:20525016, GO:0051683=PMID:20525016, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0000139=GO_REF:0000039, GO:0007030=PMID:20525016, GO:0005856=GO_REF:0000039, GO:0030659=GO_REF:0000039, GO:0005096=GO_REF:0000037} Q5T5U3 Rho GTPase-activating protein 21 protein 20120322 {GO:0005515=IPI, GO:0030054=IEA, GO:0005794=IDA, GO:0072384=IMP, GO:0051684=IMP, GO:0051683=IDA, GO:0005622=IEA, GO:0007165=IEA, GO:0005543=IEA, GO:0000139=IEA, GO:0007030=IMP, GO:0005856=IEA, GO:0030659=IEA, GO:0005096=IEA} Golgi organization, establishment of Golgi localization, maintenance of Golgi location, organelle transport along microtubule, signal transduction Golgi apparatus, Golgi membrane, cell junction, cytoplasmic vesicle membrane, cytoskeleton, intracellular GTPase activator activity, phospholipid binding, protein binding Human ARHGAP22 IntAct UniProtKB {GO:0005515=PMID:21078624, GO:0051056=Reactome:REACT_11051, GO:0006355=GO_REF:0000037, GO:0007264=Reactome:REACT_11044, GO:0005634=GO_REF:0000039, GO:0001525=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0005829=Reactome:REACT_9982, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0005096=GO_REF:0000037} Q7Z5H3 Rho GTPase-activating protein 22 protein 20130415 {GO:0005515=IPI, GO:0051056=TAS, GO:0006355=IEA, GO:0007264=TAS, GO:0005634=IEA, GO:0001525=IEA, GO:0006351=IEA, GO:0030154=IEA, GO:0005829=TAS, GO:0005622=IEA, GO:0007165=IEA, GO:0005543=IEA, GO:0005096=IEA} angiogenesis, cell differentiation, regulation of small GTPase mediated signal transduction, regulation of transcription, DNA-dependent, signal transduction, small GTPase mediated signal transduction, transcription, DNA-dependent cytosol, intracellular, nucleus GTPase activator activity, phospholipid binding, protein binding Human UniProtKB:O00555 ARHGAP23 Reactome UniProtKB {GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} Q9P227 Rho GTPase-activating protein 23 protein 20130301 {GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0005543=IEA, GO:0007264=TAS, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular GTPase activator activity, phospholipid binding Human ARHGAP24 HPA UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0005886=GO_REF:0000052, GO:0007264=Reactome:REACT_11044, GO:0001525=GO_REF:0000037, GO:0042995=GO_REF:0000039, GO:0030154=GO_REF:0000037, GO:0005829=Reactome:REACT_9982, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0005856=GO_REF:0000039, GO:0005925=GO_REF:0000039, GO:0005096=GO_REF:0000037} Q8N264 Rho GTPase-activating protein 24 protein 20100326 {GO:0051056=TAS, GO:0005886=IDA, GO:0007264=TAS, GO:0001525=IEA, GO:0042995=IEA, GO:0030154=IEA, GO:0005829=TAS, GO:0005622=IEA, GO:0007165=IEA, GO:0005737=IDA, GO:0005543=IEA, GO:0005856=IEA, GO:0005925=IEA, GO:0005096=IEA} angiogenesis, cell differentiation, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cell projection, cytoplasm, cytoskeleton, cytosol, focal adhesion, intracellular, plasma membrane GTPase activator activity, phospholipid binding Human ARHGAP25 Reactome UniProtKB {GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} P42331 Rho GTPase-activating protein 25 protein 20130301 {GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0005543=IEA, GO:0007264=TAS, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular GTPase activator activity, phospholipid binding Human ARHGAP26 GOC UniProtKB {GO:0005515=PMID:11432776, GO:0051056=Reactome:REACT_11051, GO:0017124=GO_REF:0000002, GO:0030036=PMID:11998687, GO:0007264=Reactome:REACT_11044, GO:0005575=GO_REF:0000015, GO:0005100=PMID:10908648, GO:0007399=PMID:9582072, GO:0005829=Reactome:REACT_9982, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0032321=PMID:10908648, GO:0046847=GO_REF:0000002, GO:0005856=GO_REF:0000039, GO:0005925=GO_REF:0000039, GO:0008093=GO_REF:0000002} Q9UNA1 Rho GTPase-activating protein 26 protein 20130413 {GO:0005515=IPI, GO:0051056=TAS, GO:0017124=IEA, GO:0030036=NAS, GO:0007264=TAS, GO:0005575=ND, GO:0005100=NAS, GO:0007399=NAS, GO:0005829=TAS, GO:0005622=IEA, GO:0007165=IEA, GO:0005543=IEA, GO:0032321=NAS, GO:0046847=IEA, GO:0005856=IEA, GO:0005925=IEA, GO:0008093=IEA} actin cytoskeleton organization, filopodium assembly, nervous system development, positive regulation of Rho GTPase activity, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cellular_component, cytoskeleton, cytosol, focal adhesion, intracellular Rho GTPase activator activity, SH3 domain binding, cytoskeletal adaptor activity, phospholipid binding, protein binding Human ARHGAP27 GOC UniProtKB {GO:0005622=GO_REF:0000024, GO:0007165=GO_REF:0000002, GO:0017124=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0043089=GO_REF:0000024, GO:0032855=GO_REF:0000024, GO:0030675=GO_REF:0000024, GO:0006898=GO_REF:0000024, GO:0005096=GO_REF:0000038} Q6ZUM4 Rho GTPase-activating protein 27 protein 20130413 {GO:0005622=ISS, GO:0007165=IEA, GO:0017124=ISS, GO:0005737=IEA, GO:0005543=IEA, GO:0016020=IEA, GO:0043089=ISS, GO:0032855=ISS, GO:0030675=ISS, GO:0006898=ISS, GO:0005096=IEA} positive regulation of Cdc42 GTPase activity, positive regulation of Rac GTPase activity, receptor-mediated endocytosis, signal transduction cytoplasm, intracellular, membrane GTPase activator activity, Rac GTPase activator activity, SH3 domain binding, phospholipid binding Human UniProtKB:Q6TLK4 ARHGAP28 HPA UniProtKB {GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} Q9P2N2 Rho GTPase-activating protein 28 protein 20101115 {GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0007264=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular, nucleolus, nucleus GTPase activator activity NOT Human ARHGAP29 GOC UniProtKB {GO:0035556=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0032321=PMID:9305890, GO:0007264=Reactome:REACT_11044, GO:0007266=PMID:9305890, GO:0005100=PMID:9305890, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_9982} Q52LW3 Rho GTPase-activating protein 29 protein 20130413 {GO:0035556=IEA, GO:0005622=IEA, GO:0051056=TAS, GO:0032321=TAS, GO:0007264=TAS, GO:0007266=TAS, GO:0005100=TAS, GO:0046872=IEA, GO:0005829=TAS} Rho protein signal transduction, intracellular signal transduction, positive regulation of Rho GTPase activity, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol, intracellular Rho GTPase activator activity, metal ion binding Human ARHGAP30 Reactome UniProtKB {GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0016023=GO_REF:0000039, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} Q7Z6I6 Rho GTPase-activating protein 30 protein 20130301 {GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0007264=TAS, GO:0016023=IEA, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytoplasmic membrane-bounded vesicle, cytosol, intracellular GTPase activator activity Human ARHGAP31 Reactome UniProtKB {GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0017124=GO_REF:0000019, GO:0007264=Reactome:REACT_11044, GO:0005925=GO_REF:0000039, GO:0030027=GO_REF:0000039, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000019} Q2M1Z3 Rho GTPase-activating protein 31 protein 20130301 {GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0017124=IEA, GO:0007264=TAS, GO:0005925=IEA, GO:0030027=IEA, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, focal adhesion, intracellular, lamellipodium GTPase activator activity, SH3 domain binding Human ARHGAP32 InterPro UniProtKB {GO:0005515=PMID:12788081, GO:0051056=Reactome:REACT_11051, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000037, GO:0007264=Reactome:REACT_11044, GO:0014069=GO_REF:0000039, GO:0015629=GO_REF:0000019, GO:0005829=Reactome:REACT_9982, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0007154=GO_REF:0000002, GO:0000139=GO_REF:0000039, GO:0045211=GO_REF:0000037, GO:0005789=GO_REF:0000039, GO:0035091=GO_REF:0000002, GO:0005938=GO_REF:0000039, GO:0010008=GO_REF:0000039, GO:0005096=GO_REF:0000037} G3V174 Rho GTPase-activating protein, isoform CRA_b protein 20130413 {GO:0005515=IPI, GO:0051056=TAS, GO:0030054=IEA, GO:0005886=IEA, GO:0007264=TAS, GO:0014069=IEA, GO:0015629=IEA, GO:0005829=TAS, GO:0005622=IEA, GO:0007165=IEA, GO:0007154=IEA, GO:0000139=IEA, GO:0045211=IEA, GO:0005789=IEA, GO:0035091=IEA, GO:0005938=IEA, GO:0010008=IEA, GO:0005096=IEA} cell communication, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction Golgi membrane, actin cytoskeleton, cell cortex, cell junction, cytosol, endoplasmic reticulum membrane, endosome membrane, intracellular, plasma membrane, postsynaptic density, postsynaptic membrane GTPase activator activity, phosphatidylinositol binding, protein binding Human InterPro:IPR001683 ARHGAP33 IntAct UniProtKB {GO:0005515=PMID:16777849, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0035091=GO_REF:0000002, GO:0030675=GO_REF:0000019} O14559 Rho GTPase-activating protein 33 protein 20130415 {GO:0005515=IPI, GO:0005622=IEA, GO:0007165=IEA, GO:0005737=IEA, GO:0005886=IEA, GO:0015031=IEA, GO:0035091=IEA, GO:0030675=IEA} protein transport, signal transduction cytoplasm, intracellular, plasma membrane Rac GTPase activator activity, phosphatidylinositol binding, protein binding Human UniProtKB:P06241 ARHGAP35 GOC UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0007264=Reactome:REACT_11044, GO:0008360=GO_REF:0000019, GO:0003714=PMID:1894621, GO:0001843=GO_REF:0000019, GO:0005634=PMID:1894621, GO:0005525=GO_REF:0000002, GO:0015629=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0005100=Reactome:REACT_19242, GO:0005829=Reactome:REACT_19356, GO:0032321=Reactome:REACT_19242, GO:0007411=Reactome:REACT_18266, GO:0043010=GO_REF:0000019, GO:0030900=GO_REF:0000019, GO:0045892=PMID:1894621, GO:0043116=GO_REF:0000019} Q9NRY4 Rho GTPase-activating protein 35 protein 20130413 {GO:0051056=TAS, GO:0007264=TAS, GO:0008360=IEA, GO:0003714=TAS, GO:0001843=IEA, GO:0005634=IC, GO:0005525=IEA, GO:0015629=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0005100=TAS, GO:0005829=TAS, GO:0032321=TAS, GO:0007411=TAS, GO:0043010=IEA, GO:0030900=IEA, GO:0045892=IDA, GO:0043116=IEA} axon guidance, camera-type eye development, forebrain development, negative regulation of transcription, DNA-dependent, negative regulation of vascular permeability, neural tube closure, positive regulation of Rho GTPase activity, regulation of cell shape, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction, transcription, DNA-dependent actin cytoskeleton, cytosol, nucleus DNA binding, GTP binding, Rho GTPase activator activity, transcription corepressor activity Human ARHGAP39 Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0007411=Reactome:REACT_18266, GO:0007264=Reactome:REACT_11044, GO:0005634=GO_REF:0000039, GO:0005856=GO_REF:0000002, GO:0005829=Reactome:REACT_9982} Q9C0H5 Rho GTPase-activating protein 39 protein 20130301 {GO:0051056=TAS, GO:0007411=TAS, GO:0007264=TAS, GO:0005634=IEA, GO:0005856=IEA, GO:0005829=TAS} axon guidance, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytoskeleton, cytosol, nucleus Human ARHGAP4 GOC UniProtKB {GO:0005515=PMID:16417406, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0007264=Reactome:REACT_11044, GO:0005730=GO_REF:0000052, GO:0006915=Reactome:REACT_13638, GO:0005634=GO_REF:0000052, GO:0007266=PMID:8570618, GO:0097190=Reactome:REACT_13720, GO:0005100=PMID:8570618, GO:0005829=Reactome:REACT_19216, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0032321=PMID:8570618, GO:0005070=PMID:8570618, GO:0007010=PMID:8570618, GO:0005925=GO_REF:0000052} P98171 Rho GTPase-activating protein 4 protein 20130413 {GO:0005515=IPI, GO:0051056=TAS, GO:0048011=TAS, GO:0007264=TAS, GO:0005730=IDA, GO:0006915=TAS, GO:0005634=IDA, GO:0007266=TAS, GO:0097190=TAS, GO:0005100=TAS, GO:0005829=TAS, GO:0005622=IEA, GO:0007165=IEA, GO:0005737=IDA, GO:0032321=TAS, GO:0005070=TAS, GO:0007010=TAS, GO:0005925=IDA} Rho protein signal transduction, apoptotic process, apoptotic signaling pathway, cytoskeleton organization, neurotrophin TRK receptor signaling pathway, positive regulation of Rho GTPase activity, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytoplasm, cytosol, focal adhesion, intracellular, nucleolus, nucleus Rho GTPase activator activity, SH3/SH2 adaptor activity, protein binding Human ARHGAP44 Reactome UniProtKB {GO:0005515=PMID:19273615, GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} Q17R89 Rho GTPase-activating protein 44 protein 20130301 {GO:0005515=IPI, GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0005737=IEA, GO:0007264=TAS, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytoplasm, cytosol, intracellular GTPase activator activity, protein binding Human ARHGAP5 GOC UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0008361=GO_REF:0000019, GO:0030335=GO_REF:0000019, GO:0007264=Reactome:REACT_11044, GO:0003924=PMID:8537347, GO:0002053=GO_REF:0000019, GO:0007266=PMID:8537347, GO:0005525=GO_REF:0000002, GO:0005100=PMID:8537347, GO:0005829=Reactome:REACT_9982, GO:0006184=PMID:8537347, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0005737=PMID:8537347, GO:0016020=GO_REF:0000039, GO:0032321=PMID:8537347, GO:0007155=PMID:8537347, GO:0042169=PMID:1689011} Q13017 Rho GTPase-activating protein 5 protein 20130413 {GO:0051056=TAS, GO:0008361=IEA, GO:0030335=IEA, GO:0007264=TAS, GO:0003924=TAS, GO:0002053=IEA, GO:0007266=TAS, GO:0005525=IEA, GO:0005100=TAS, GO:0005829=TAS, GO:0006184=TAS, GO:0005622=IEA, GO:0007165=IEA, GO:0005737=TAS, GO:0016020=IEA, GO:0032321=TAS, GO:0007155=TAS, GO:0042169=IPI} GTP catabolic process, Rho protein signal transduction, cell adhesion, positive regulation of Rho GTPase activity, positive regulation of cell migration, positive regulation of mesenchymal cell proliferation, regulation of cell size, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytoplasm, cytosol, intracellular, membrane GTP binding, GTPase activity, Rho GTPase activator activity, SH2 domain binding Human ARHGAP6 BHF-UCL UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0017124=GO_REF:0000037, GO:0007264=Reactome:REACT_11044, GO:0005884=PMID:10699171, GO:0007266=PMID:10699171, GO:0015629=PMID:10699171, GO:0043087=PMID:10699171, GO:0005100=PMID:10699171, GO:0051895=PMID:10699171, GO:0005829=Reactome:REACT_9982, GO:0051497=PMID:10699171, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0005737=PMID:10699171, GO:0048041=GO_REF:0000019, GO:0005070=PMID:8570618, GO:0030041=PMID:10699171} O43182 Rho GTPase-activating protein 6 protein 20081126 {GO:0051056=TAS, GO:0017124=IEA, GO:0007264=TAS, GO:0005884=NAS, GO:0007266=NAS, GO:0015629=ISS, GO:0043087=ISS, GO:0005100=ISS, GO:0051895=IMP, GO:0005829=TAS, GO:0051497=IMP, GO:0005622=IEA, GO:0007165=IEA, GO:0005737=IMP, GO:0048041=IEA, GO:0005070=TAS, GO:0030041=NAS} Rho protein signal transduction, actin filament polymerization, focal adhesion assembly, negative regulation of focal adhesion assembly, negative regulation of stress fiber assembly, regulation of GTPase activity, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction actin cytoskeleton, actin filament, cytoplasm, cytosol, intracellular Rho GTPase activator activity, SH3 domain binding, SH3/SH2 adaptor activity Human ARHGAP8 GOC UniProtKB {GO:0005515=PMID:20179103, GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0032321=PMID:20179103, GO:0007264=Reactome:REACT_11044, GO:0070374=PMID:20179103, GO:0005100=PMID:20179103, GO:0005829=Reactome:REACT_9982} P85298 Rho GTPase-activating protein 8 protein 20130413 {GO:0005515=IPI, GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0032321=IDA, GO:0007264=TAS, GO:0070374=IDA, GO:0005100=IDA, GO:0005829=TAS} positive regulation of ERK1 and ERK2 cascade, positive regulation of Rho GTPase activity, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular Rho GTPase activator activity, protein binding Human ARHGAP9 GOC UniProtKB {GO:0043547=PMID:11396949, GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0005829=Reactome:REACT_9982, GO:0005096=PMID:11396949} Q9BRR9 Rho GTPase-activating protein 9 protein 20130413 {GO:0043547=IDA, GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0005543=IEA, GO:0007264=TAS, GO:0005829=TAS, GO:0005096=IDA} positive regulation of GTPase activity, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular GTPase activator activity, phospholipid binding Human ARHGDIA IntAct UniProtKB {GO:0005515=PMID:20711218, GO:0001772=GO_REF:0000019, GO:0051056=Reactome:REACT_11051, GO:0043066=PMID:16130169, GO:0048011=Reactome:REACT_13776, GO:0007264=Reactome:REACT_11044, GO:0006928=PMID:16130169, GO:0007266=GO_REF:0000019, GO:0005829=Reactome:REACT_13771, GO:0032880=GO_REF:0000019, GO:0005737=GO_REF:0000002, GO:0007162=PMID:8262133, GO:0050771=Reactome:REACT_13815, GO:0050772=Reactome:REACT_13779, GO:0005856=PMID:16130169, GO:0050770=Reactome:REACT_13620, GO:0005094=GO_REF:0000019, GO:0005096=GO_REF:0000037} P52565 Rho GDP-dissociation inhibitor 1 protein 20130415 {GO:0005515=IPI, GO:0001772=IEA, GO:0051056=TAS, GO:0043066=TAS, GO:0048011=TAS, GO:0007264=TAS, GO:0006928=TAS, GO:0007266=IEA, GO:0005829=TAS, GO:0032880=IEA, GO:0005737=IEA, GO:0007162=TAS, GO:0050771=TAS, GO:0050772=TAS, GO:0005856=TAS, GO:0050770=TAS, GO:0005094=IEA, GO:0005096=IEA} Rho protein signal transduction, cellular component movement, negative regulation of apoptotic process, negative regulation of axonogenesis, negative regulation of cell adhesion, neurotrophin TRK receptor signaling pathway, positive regulation of axonogenesis, regulation of axonogenesis, regulation of protein localization, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytoplasm, cytoskeleton, cytosol, immunological synapse GTPase activator activity, Rho GDP-dissociation inhibitor activity, protein binding Human UniProtKB:P61586 ARHGDIB Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0030036=PMID:8262133, GO:0007264=Reactome:REACT_11044, GO:0006928=PMID:16130169, GO:0007275=PMID:8434008, GO:0007266=PMID:8356058, GO:0005829=Reactome:REACT_10055, GO:0005737=PMID:16130169, GO:0006955=PMID:8356058, GO:0007162=PMID:9113980, GO:0016023=PMID:9113980, GO:0005856=PMID:16130169, GO:0005094=GO_REF:0000002, GO:0005096=GO_REF:0000037} P52566 Rho GDP-dissociation inhibitor 2 protein 20130301 {GO:0051056=TAS, GO:0030036=TAS, GO:0007264=TAS, GO:0006928=TAS, GO:0007275=TAS, GO:0007266=TAS, GO:0005829=TAS, GO:0005737=TAS, GO:0006955=TAS, GO:0007162=TAS, GO:0016023=TAS, GO:0005856=TAS, GO:0005094=IEA, GO:0005096=IEA} Rho protein signal transduction, actin cytoskeleton organization, cellular component movement, immune response, multicellular organismal development, negative regulation of cell adhesion, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytoplasm, cytoplasmic membrane-bounded vesicle, cytoskeleton, cytosol GTPase activator activity, Rho GDP-dissociation inhibitor activity Human ARHGDIG Reactome UniProtKB {GO:0032880=GO_REF:0000019, GO:0051056=Reactome:REACT_11051, GO:0007162=PMID:9113980, GO:0005737=GO_REF:0000002, GO:0016020=GO_REF:0000019, GO:0007264=Reactome:REACT_11044, GO:0016023=PMID:9113980, GO:0007266=PMID:9113980, GO:0005094=GO_REF:0000002, GO:0005829=Reactome:REACT_10055, GO:0005096=GO_REF:0000037} Q99819 Rho GDP-dissociation inhibitor 3 protein 20130301 {GO:0032880=IEA, GO:0051056=TAS, GO:0007162=TAS, GO:0005737=IEA, GO:0016020=IEA, GO:0007264=TAS, GO:0016023=TAS, GO:0007266=TAS, GO:0005094=IEA, GO:0005829=TAS, GO:0005096=IEA} Rho protein signal transduction, negative regulation of cell adhesion, regulation of protein localization, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytoplasm, cytoplasmic membrane-bounded vesicle, cytosol, membrane GTPase activator activity, Rho GDP-dissociation inhibitor activity Human ARHGEF1 HPA UniProtKB {GO:0005515=PMID:12681510, GO:0048011=Reactome:REACT_13776, GO:0005886=Reactome:REACT_56, GO:0035023=GO_REF:0000002, GO:0008283=PMID:8810315, GO:0038032=GO_REF:0000002, GO:0007266=PMID:10747909, GO:0005829=Reactome:REACT_56, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0050771=Reactome:REACT_13815, GO:0005089=GO_REF:0000002, GO:0050770=Reactome:REACT_13620, GO:0005096=GO_REF:0000037} Q92888 Rho guanine nucleotide exchange factor 1 protein 20081203 {GO:0005515=IPI, GO:0048011=TAS, GO:0005886=TAS, GO:0035023=IEA, GO:0008283=TAS, GO:0038032=IEA, GO:0007266=TAS, GO:0005829=TAS, GO:0005622=IEA, GO:0005737=IDA, GO:0005543=IEA, GO:0050771=TAS, GO:0005089=IEA, GO:0050770=TAS, GO:0005096=IEA} Rho protein signal transduction, cell proliferation, negative regulation of axonogenesis, neurotrophin TRK receptor signaling pathway, regulation of Rho protein signal transduction, regulation of axonogenesis, termination of G-protein coupled receptor signaling pathway cytoplasm, cytosol, intracellular, plasma membrane GTPase activator activity, Rho guanyl-nucleotide exchange factor activity, phospholipid binding, protein binding Human ARHGEF10 BHF-UCL UniProtKB {GO:0005622=GO_REF:0000002, GO:0051298=PMID:19635168, GO:0005813=PMID:19635168, GO:0035023=GO_REF:0000002, GO:0022011=PMID:14508709, GO:0051496=PMID:16896804, GO:0033126=PMID:19635168, GO:0019894=PMID:19635168, GO:0090307=PMID:19635168, GO:0005089=PMID:20042462, GO:0005829=PMID:16896804} O15013 Rho guanine nucleotide exchange factor 10 protein 20110614 {GO:0005622=IEA, GO:0051298=IMP, GO:0005813=IDA, GO:0035023=IEA, GO:0022011=IMP, GO:0051496=IMP, GO:0033126=IDA, GO:0019894=IPI, GO:0090307=IMP, GO:0005089=IDA, GO:0005829=NAS} centrosome duplication, myelination in peripheral nervous system, positive regulation of GTP catabolic process, positive regulation of stress fiber assembly, regulation of Rho protein signal transduction, spindle assembly involved in mitosis centrosome, cytosol, intracellular Rho guanyl-nucleotide exchange factor activity, kinesin binding Human ARHGEF10L UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0032933=PMID:16112081, GO:0032321=PMID:16112081, GO:0035023=GO_REF:0000002, GO:0051496=PMID:16112081, GO:0005089=GO_REF:0000002, GO:0005100=PMID:16112081, GO:0005829=PMID:16112081} Q9HCE6 Rho guanine nucleotide exchange factor 10-like protein protein 20130413 {GO:0005622=IEA, GO:0005737=IEA, GO:0032933=IDA, GO:0032321=IDA, GO:0035023=IEA, GO:0051496=IDA, GO:0005089=IEA, GO:0005100=IDA, GO:0005829=IDA} SREBP signaling pathway, positive regulation of Rho GTPase activity, positive regulation of stress fiber assembly, regulation of Rho protein signal transduction cytoplasm, cytosol, intracellular Rho GTPase activator activity, Rho guanyl-nucleotide exchange factor activity Human UniProtKB-SubCell:SL-0086 ARHGEF11 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0030036=PMID:10026210, GO:0035023=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0006941=PMID:10026210, GO:0038032=GO_REF:0000002, GO:0006928=PMID:10026210, GO:0030010=PMID:10026210, GO:0007266=PMID:10026210, GO:0001558=PMID:10026210, GO:0005829=Reactome:REACT_19216, GO:0005622=PMID:10026210, GO:0000910=PMID:10026210, GO:0005737=PMID:15755723, GO:0005543=GO_REF:0000002, GO:0007411=Reactome:REACT_18266, GO:0005089=PMID:10026210, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0001664=PMID:15755723, GO:0006915=Reactome:REACT_13638, GO:0097190=Reactome:REACT_13720, GO:0016020=GO_REF:0000039, GO:0007186=PMID:15755723, GO:0045893=PMID:10026210, GO:0005096=GO_REF:0000037} O15085 Rho guanine nucleotide exchange factor 11 protein 20130415 {GO:0005515=IPI, GO:0030036=NAS, GO:0035023=IEA, GO:0007264=TAS, GO:0006941=NAS, GO:0038032=IEA, GO:0006928=NAS, GO:0030010=NAS, GO:0007266=IDA, GO:0001558=NAS, GO:0005829=TAS, GO:0005622=IC, GO:0000910=NAS, GO:0005737=IDA, GO:0005543=IEA, GO:0007411=TAS, GO:0005089=TAS, GO:0051056=TAS, GO:0048011=TAS, GO:0001664=IDA, GO:0006915=TAS, GO:0097190=TAS, GO:0016020=IEA, GO:0007186=IDA, GO:0045893=IDA, GO:0005096=IEA} G-protein coupled receptor signaling pathway, Rho protein signal transduction, actin cytoskeleton organization, apoptotic process, apoptotic signaling pathway, axon guidance, cellular component movement, cytokinesis, establishment of cell polarity, neurotrophin TRK receptor signaling pathway, positive regulation of transcription, DNA-dependent, regulation of Rho protein signal transduction, regulation of cell growth, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction, striated muscle contraction, termination of G-protein coupled receptor signaling pathway cytoplasm, cytosol, intracellular, membrane G-protein coupled receptor binding, GTPase activator activity, Rho guanyl-nucleotide exchange factor activity, phospholipid binding, protein binding Human UniProtKB:P61586 ARHGEF12 Reactome UniProtKB {GO:0005515=PMID:20844236, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0001664=PMID:15755723, GO:0007264=Reactome:REACT_11044, GO:0035023=GO_REF:0000002, GO:0038032=GO_REF:0000002, GO:0006915=Reactome:REACT_13638, GO:0097190=Reactome:REACT_13720, GO:0005829=Reactome:REACT_19360, GO:0035556=GO_REF:0000002, GO:0005737=PMID:15755723, GO:0005543=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0007186=PMID:15755723, GO:0007411=Reactome:REACT_18266, GO:0005089=GO_REF:0000002, GO:0005096=GO_REF:0000037} Q9NZN5 Rho guanine nucleotide exchange factor 12 protein 20130301 {GO:0005515=IPI, GO:0051056=TAS, GO:0048011=TAS, GO:0001664=IDA, GO:0007264=TAS, GO:0035023=IEA, GO:0038032=IEA, GO:0006915=TAS, GO:0097190=TAS, GO:0005829=TAS, GO:0035556=IEA, GO:0005737=IDA, GO:0005543=IEA, GO:0016020=IEA, GO:0007186=IDA, GO:0007411=TAS, GO:0005089=IEA, GO:0005096=IEA} G-protein coupled receptor signaling pathway, apoptotic process, apoptotic signaling pathway, axon guidance, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction, termination of G-protein coupled receptor signaling pathway cytoplasm, cytosol, membrane G-protein coupled receptor binding, GTPase activator activity, Rho guanyl-nucleotide exchange factor activity, phospholipid binding, protein binding Human ARHGEF15 UniProtKB UniProtKB {GO:0005515=PMID:12775584, GO:0005622=GO_REF:0000002, GO:0050790=PMID:12775584, GO:0035023=GO_REF:0000002, GO:2000297=GO_REF:0000024, GO:0005089=PMID:12775584, GO:0030425=GO_REF:0000024, GO:0005096=GO_REF:0000037} O94989 Rho guanine nucleotide exchange factor 15 protein 20110923 {GO:0005515=IPI, GO:0005622=IEA, GO:0050790=IDA, GO:0035023=IEA, GO:2000297=ISS, GO:0005089=IDA, GO:0030425=ISS, GO:0005096=IEA} negative regulation of synapse maturation, regulation of Rho protein signal transduction, regulation of catalytic activity dendrite, intracellular GTPase activator activity, Rho guanyl-nucleotide exchange factor activity, protein binding Human ARHGEF16 BHF-UCL UniProtKB {GO:0005515=PMID:20679435, GO:0051056=Reactome:REACT_11051, GO:0030971=PMID:20679435, GO:0048011=Reactome:REACT_13776, GO:0035023=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0006915=Reactome:REACT_13638, GO:0030165=PMID:21139582, GO:0032863=PMID:20679435, GO:0032864=PMID:21139582, GO:0097190=Reactome:REACT_13720, GO:0005829=Reactome:REACT_19216, GO:0005622=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0060326=PMID:20679435, GO:0017048=PMID:20679435, GO:0005089=PMID:20679435, GO:0090004=PMID:20679435} Q5VV41 Rho guanine nucleotide exchange factor 16 protein 20101230 {GO:0005515=IPI, GO:0051056=TAS, GO:0030971=IPI, GO:0048011=TAS, GO:0035023=IEA, GO:0007264=TAS, GO:0006915=TAS, GO:0030165=IPI, GO:0032863=IMP, GO:0032864=IDA, GO:0097190=TAS, GO:0005829=TAS, GO:0005622=IEA, GO:0005543=IEA, GO:0060326=IMP, GO:0017048=IPI, GO:0005089=IDA, GO:0090004=IMP} activation of Cdc42 GTPase activity, activation of Rac GTPase activity, apoptotic process, apoptotic signaling pathway, cell chemotaxis, neurotrophin TRK receptor signaling pathway, positive regulation of establishment of protein localization to plasma membrane, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol, intracellular PDZ domain binding, Rho GTPase binding, Rho guanyl-nucleotide exchange factor activity, phospholipid binding, protein binding, receptor tyrosine kinase binding Human UniProtKB:O14907 ARHGEF17 Reactome UniProtKB {GO:0005085=PMID:12071859, GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0030036=PMID:12071859, GO:0007264=Reactome:REACT_11044, GO:0035023=GO_REF:0000002, GO:0006915=Reactome:REACT_13638, GO:0005089=GO_REF:0000002, GO:0097190=Reactome:REACT_13720, GO:0005829=Reactome:REACT_19216} Q96PE2 Rho guanine nucleotide exchange factor 17 protein 20130301 {GO:0005085=IDA, GO:0005622=IEA, GO:0051056=TAS, GO:0048011=TAS, GO:0030036=IDA, GO:0007264=TAS, GO:0035023=IEA, GO:0006915=TAS, GO:0005089=IEA, GO:0097190=TAS, GO:0005829=TAS} actin cytoskeleton organization, apoptotic process, apoptotic signaling pathway, neurotrophin TRK receptor signaling pathway, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol, intracellular Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity Human ARHGEF18 HPA UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0030036=PMID:14512443, GO:0030054=Reactome:REACT_121319, GO:0005886=GO_REF:0000052, GO:0035023=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0008360=PMID:14512443, GO:0045177=PMID:22006950, GO:0006915=Reactome:REACT_13638, GO:0097190=Reactome:REACT_13720, GO:0005829=Reactome:REACT_19216, GO:0005622=GO_REF:0000002, GO:0005085=PMID:14512443, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0007179=Reactome:REACT_120726, GO:0005089=GO_REF:0000002} Q6ZSZ5 Rho guanine nucleotide exchange factor 18 protein 20111111 {GO:0051056=TAS, GO:0048011=TAS, GO:0030036=IDA, GO:0030054=TAS, GO:0005886=IDA, GO:0035023=IEA, GO:0007264=TAS, GO:0008360=IDA, GO:0045177=IDA, GO:0006915=TAS, GO:0097190=TAS, GO:0005829=TAS, GO:0005622=IEA, GO:0005085=IDA, GO:0005737=IDA, GO:0005543=IEA, GO:0007179=TAS, GO:0005089=IEA} actin cytoskeleton organization, apoptotic process, apoptotic signaling pathway, neurotrophin TRK receptor signaling pathway, regulation of Rho protein signal transduction, regulation of cell shape, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction, transforming growth factor beta receptor signaling pathway apical part of cell, cell junction, cytoplasm, cytosol, intracellular, plasma membrane Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, phospholipid binding Human ARHGEF19 MGI UniProtKB {GO:0005622=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0032321=GO_REF:0000019, GO:0035023=GO_REF:0000002, GO:0032956=PMID:20643356, GO:0042060=GO_REF:0000019, GO:0005089=GO_REF:0000002, GO:0005096=GO_REF:0000037} Q8IW93 Rho guanine nucleotide exchange factor 19 protein 20101206 {GO:0005622=IEA, GO:0005543=IEA, GO:0032321=IEA, GO:0035023=IEA, GO:0032956=IGI, GO:0042060=IEA, GO:0005089=IEA, GO:0005096=IEA} positive regulation of Rho GTPase activity, regulation of Rho protein signal transduction, regulation of actin cytoskeleton organization, wound healing intracellular GTPase activator activity, Rho guanyl-nucleotide exchange factor activity, phospholipid binding Human UniProtKB:Q8TE85 ARHGEF2 BHF-UCL UniProtKB {GO:0005515=PMID:19043560, GO:0008017=PMID:9857026, GO:0007264=Reactome:REACT_11044, GO:0035023=PMID:11912491, GO:0000132=GO_REF:0000019, GO:0006886=PMID:9857026, GO:0046872=GO_REF:0000038, GO:0005829=Reactome:REACT_19216, GO:0035556=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0051092=PMID:19043560, GO:0005543=GO_REF:0000002, GO:0050768=GO_REF:0000019, GO:0043198=GO_REF:0000019, GO:0042127=PMID:9857026, GO:0071356=GO_REF:0000024, GO:0043025=GO_REF:0000019, GO:0060547=GO_REF:0000024, GO:0007015=PMID:9857026, GO:0005089=PMID:9857026, GO:0030676=PMID:9857026, GO:0071474=GO_REF:0000024, GO:0051056=Reactome:REACT_11051, GO:0043066=GO_REF:0000024, GO:0048011=Reactome:REACT_13776, GO:0005794=GO_REF:0000039, GO:0005874=PMID:9857026, GO:0005819=GO_REF:0000039, GO:0006915=Reactome:REACT_13638, GO:0032587=PMID:19043560, GO:0097190=Reactome:REACT_13720, GO:0048365=PMID:9857026, GO:0000902=PMID:11912491, GO:0007067=GO_REF:0000037, GO:0007026=PMID:11912491, GO:0008270=PMID:11912491, GO:0017048=PMID:9857026, GO:0005923=GO_REF:0000039, GO:0008134=GO_REF:0000024, GO:0051301=GO_REF:0000037} Q92974 Rho guanine nucleotide exchange factor 2 protein 20130114 {GO:0005515=IPI, GO:0008017=IDA, GO:0007264=TAS, GO:0035023=NAS, GO:0000132=IEA, GO:0006886=NAS, GO:0046872=IEA, GO:0005829=TAS, GO:0035556=IEA, GO:0005622=IEA, GO:0051092=IDA, GO:0005543=IEA, GO:0050768=IEA, GO:0043198=IEA, GO:0042127=TAS, GO:0071356=ISS, GO:0043025=IEA, GO:0060547=ISS, GO:0007015=IMP, GO:0005089=IDA, GO:0030676=IDA, GO:0071474=ISS, GO:0051056=TAS, GO:0043066=ISS, GO:0048011=TAS, GO:0005794=IEA, GO:0005874=IDA, GO:0005819=IEA, GO:0006915=TAS, GO:0032587=IDA, GO:0097190=TAS, GO:0048365=IDA, GO:0000902=IMP, GO:0007067=IEA, GO:0007026=IMP, GO:0008270=NAS, GO:0017048=IDA, GO:0005923=IEA, GO:0008134=ISS, GO:0051301=IEA} actin filament organization, apoptotic process, apoptotic signaling pathway, cell division, cell morphogenesis, cellular hyperosmotic response, cellular response to tumor necrosis factor, establishment of mitotic spindle orientation, intracellular protein transport, intracellular signal transduction, mitosis, negative regulation of apoptotic process, negative regulation of microtubule depolymerization, negative regulation of necrotic cell death, negative regulation of neurogenesis, neurotrophin TRK receptor signaling pathway, positive regulation of NF-kappaB transcription factor activity, regulation of Rho protein signal transduction, regulation of cell proliferation, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction Golgi apparatus, cytosol, dendritic shaft, intracellular, microtubule, neuronal cell body, ruffle membrane, spindle, tight junction Rac GTPase binding, Rac guanyl-nucleotide exchange factor activity, Rho GTPase binding, Rho guanyl-nucleotide exchange factor activity, metal ion binding, microtubule binding, phospholipid binding, protein binding, transcription factor binding, zinc ion binding Human UniProtKB:Q865S3 ARHGEF25 Reactome UniProtKB {GO:0005622=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0005886=GO_REF:0000024, GO:0035023=GO_REF:0000002, GO:0030016=GO_REF:0000024, GO:0005089=GO_REF:0000002, GO:0030017=GO_REF:0000039, GO:0005829=Reactome:REACT_19301} Q86VW2 Rho guanine nucleotide exchange factor 25 protein 20090911 {GO:0005622=IEA, GO:0005543=IEA, GO:0005886=ISS, GO:0035023=IEA, GO:0030016=ISS, GO:0005089=IEA, GO:0030017=IEA, GO:0005829=TAS} regulation of Rho protein signal transduction cytosol, intracellular, myofibril, plasma membrane, sarcomere Rho guanyl-nucleotide exchange factor activity, phospholipid binding Human ARHGEF3 LIFEdb UniProtKB {GO:0035556=GO_REF:0000002, GO:0005622=GO_REF:0000054, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0005543=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0035023=GO_REF:0000002, GO:0006915=Reactome:REACT_13638, GO:0007266=PMID:10873612, GO:0005089=GO_REF:0000002, GO:0097190=Reactome:REACT_13720, GO:0005829=Reactome:REACT_19216} Q9NR81 Rho guanine nucleotide exchange factor 3 protein 20100607 {GO:0035556=IEA, GO:0005622=IDA, GO:0051056=TAS, GO:0048011=TAS, GO:0005543=IEA, GO:0007264=TAS, GO:0035023=IEA, GO:0006915=TAS, GO:0007266=TAS, GO:0005089=IEA, GO:0097190=TAS, GO:0005829=TAS} Rho protein signal transduction, apoptotic process, apoptotic signaling pathway, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol, intracellular Rho guanyl-nucleotide exchange factor activity, phospholipid binding Human ARHGEF35 null null {} null null null null {} null null null ARHGEF4 Reactome UniProtKB {GO:0005515=PMID:17588722, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0007264=Reactome:REACT_11044, GO:0035023=GO_REF:0000002, GO:0019904=PMID:10947987, GO:0030032=PMID:17599059, GO:0006915=Reactome:REACT_13638, GO:0032587=GO_REF:0000039, GO:0097190=Reactome:REACT_13720, GO:0005829=Reactome:REACT_19216, GO:0035556=GO_REF:0000029, GO:0005085=PMID:17599059, GO:0005622=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0046847=PMID:17599059, GO:0005089=GO_REF:0000029, GO:0030676=PMID:17599059} Q9NR80 Rho guanine nucleotide exchange factor 4 protein 20130301 {GO:0005515=IPI, GO:0051056=TAS, GO:0048011=TAS, GO:0007264=TAS, GO:0035023=IEA, GO:0019904=IPI, GO:0030032=IMP, GO:0006915=TAS, GO:0032587=IEA, GO:0097190=TAS, GO:0005829=TAS, GO:0035556=NAS, GO:0005085=IMP, GO:0005622=IEA, GO:0005543=IEA, GO:0046847=IMP, GO:0005089=NAS, GO:0030676=IMP} apoptotic process, apoptotic signaling pathway, filopodium assembly, intracellular signal transduction, lamellipodium assembly, neurotrophin TRK receptor signaling pathway, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol, intracellular, ruffle membrane Rac guanyl-nucleotide exchange factor activity, Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, phospholipid binding, protein binding, protein domain specific binding Human ARHGEF40 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0035023=GO_REF:0000002, GO:0005089=GO_REF:0000002} Q8TER5 Rho guanine nucleotide exchange factor 40 protein 20130413 {GO:0005737=IEA, GO:0005543=IEA, GO:0035023=IEA, GO:0005089=IEA} regulation of Rho protein signal transduction cytoplasm Rho guanyl-nucleotide exchange factor activity, phospholipid binding Human UniProtKB-SubCell:SL-0086 ARHGEF5 HPA UniProtKB {GO:0035556=GO_REF:0000002, GO:0071803=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0030036=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0032321=GO_REF:0000019, GO:0035023=GO_REF:0000002, GO:0002408=GO_REF:0000019, GO:0005525=PMID:8134109, GO:0032319=PMID:21525037, GO:0005089=GO_REF:0000002} Q12774 Rho guanine nucleotide exchange factor 5 protein 20101115 {GO:0035556=IEA, GO:0071803=IEA, GO:0005737=IDA, GO:0030036=IEA, GO:0005543=IEA, GO:0005886=IDA, GO:0032321=IEA, GO:0035023=IEA, GO:0002408=IEA, GO:0005525=TAS, GO:0032319=IDA, GO:0005089=IEA} actin cytoskeleton organization, intracellular signal transduction, myeloid dendritic cell chemotaxis, positive regulation of Rho GTPase activity, positive regulation of podosome assembly, regulation of Rho GTPase activity, regulation of Rho protein signal transduction cytoplasm, plasma membrane GTP binding, Rho guanyl-nucleotide exchange factor activity, phospholipid binding Human ARHGEF6 GOC UniProtKB {GO:0005515=PMID:21295525, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0035023=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0034329=Reactome:REACT_20676, GO:0030032=GO_REF:0000024, GO:0007254=PMID:11564864, GO:0006915=Reactome:REACT_13638, GO:0097190=Reactome:REACT_13720, GO:0030027=GO_REF:0000024, GO:0005829=Reactome:REACT_20672, GO:0043547=PMID:9582122, GO:0005622=PMID:11017088, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0005089=PMID:11017088, GO:0005096=PMID:9582122} Q15052 Rho guanine nucleotide exchange factor 6 protein 20130413 {GO:0005515=IPI, GO:0051056=TAS, GO:0048011=TAS, GO:0035023=IEA, GO:0007264=TAS, GO:0034329=TAS, GO:0030032=ISS, GO:0007254=NAS, GO:0006915=TAS, GO:0097190=TAS, GO:0030027=ISS, GO:0005829=TAS, GO:0043547=NAS, GO:0005622=IC, GO:0005737=IDA, GO:0005543=IEA, GO:0005089=NAS, GO:0005096=NAS} JNK cascade, apoptotic process, apoptotic signaling pathway, cell junction assembly, lamellipodium assembly, neurotrophin TRK receptor signaling pathway, positive regulation of GTPase activity, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytoplasm, cytosol, intracellular, lamellipodium GTPase activator activity, Rho guanyl-nucleotide exchange factor activity, phospholipid binding, protein binding Human ARHGEF7 BHF-UCL UniProtKB {GO:0005515=PMID:21295525, GO:0043005=PMID:21048939, GO:0035023=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0030032=GO_REF:0000024, GO:0005829=Reactome:REACT_19216, GO:0005085=PMID:21048939, GO:0035556=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0007173=Reactome:REACT_9417, GO:0043025=PMID:21048939, GO:0005089=GO_REF:0000002, GO:0005938=GO_REF:0000039, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0043065=PMID:19041750, GO:0019901=PMID:21048939, GO:0042059=Reactome:REACT_12484, GO:0006915=Reactome:REACT_13638, GO:0001726=GO_REF:0000039, GO:0097190=Reactome:REACT_13720, GO:0030027=GO_REF:0000024, GO:0007399=GO_REF:0000037, GO:0043547=PMID:21048939, GO:0043234=PMID:11864573, GO:0007165=PMID:9659915, GO:0005925=GO_REF:0000039} Q14155 Rho guanine nucleotide exchange factor 7 protein 20120315 {GO:0005515=IPI, GO:0043005=IDA, GO:0035023=IEA, GO:0007264=TAS, GO:0030032=ISS, GO:0005829=TAS, GO:0005085=IDA, GO:0035556=IEA, GO:0005622=IEA, GO:0005543=IEA, GO:0007173=TAS, GO:0043025=IDA, GO:0005089=IEA, GO:0005938=IEA, GO:0051056=TAS, GO:0048011=TAS, GO:0043065=IMP, GO:0019901=IPI, GO:0042059=TAS, GO:0006915=TAS, GO:0001726=IEA, GO:0097190=TAS, GO:0030027=ISS, GO:0007399=IEA, GO:0043547=IDA, GO:0043234=IDA, GO:0007165=TAS, GO:0005925=IEA} apoptotic process, apoptotic signaling pathway, epidermal growth factor receptor signaling pathway, intracellular signal transduction, lamellipodium assembly, negative regulation of epidermal growth factor receptor signaling pathway, nervous system development, neurotrophin TRK receptor signaling pathway, positive regulation of GTPase activity, positive regulation of apoptotic process, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cell cortex, cytosol, focal adhesion, intracellular, lamellipodium, neuron projection, neuronal cell body, protein complex, ruffle Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, phospholipid binding, protein binding, protein kinase binding Human ARHGEF9 Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0035023=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0006915=Reactome:REACT_13638, GO:0007268=Reactome:REACT_13685, GO:0055085=Reactome:REACT_15518, GO:0097190=Reactome:REACT_13720, GO:0005829=Reactome:REACT_25130, GO:0005622=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0034220=Reactome:REACT_25387, GO:0005089=GO_REF:0000002} O43307 Rho guanine nucleotide exchange factor 9 protein 20130301 {GO:0051056=TAS, GO:0048011=TAS, GO:0035023=IEA, GO:0007264=TAS, GO:0006915=TAS, GO:0007268=TAS, GO:0055085=TAS, GO:0097190=TAS, GO:0005829=TAS, GO:0005622=IEA, GO:0005543=IEA, GO:0034220=TAS, GO:0005089=IEA} apoptotic process, apoptotic signaling pathway, ion transmembrane transport, neurotrophin TRK receptor signaling pathway, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction, synaptic transmission, transmembrane transport cytosol, intracellular Rho guanyl-nucleotide exchange factor activity, phospholipid binding Human ARID1A ENSEMBL UniProtKB {GO:0005515=PMID:17363140, GO:0016922=PMID:17363140, GO:0000790=PMID:17363140, GO:0071565=GO_REF:0000019, GO:0006357=PMID:8804307, GO:0003713=PMID:8804307, GO:0006325=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006337=PMID:8895581, GO:0071564=GO_REF:0000019, GO:0003677=PMID:10757798, GO:0006351=GO_REF:0000037, GO:0007399=GO_REF:0000037, GO:0016514=GO_REF:0000019, GO:0042921=PMID:12200431, GO:0042766=PMID:12200431, GO:0006338=PMID:11726552, GO:0045893=PMID:12200431, GO:0048096=PMID:12200431, GO:0030521=PMID:12200431, GO:0030520=PMID:12200431} Q96SM7 AT-rich interactive domain-containing protein 1A protein 20130413 {GO:0005515=IPI, GO:0016922=IPI, GO:0000790=IDA, GO:0071565=IEA, GO:0006357=NAS, GO:0003713=NAS, GO:0006325=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006337=IDA, GO:0071564=IEA, GO:0003677=NAS, GO:0006351=IEA, GO:0007399=IEA, GO:0016514=IEA, GO:0042921=IDA, GO:0042766=TAS, GO:0006338=IDA, GO:0045893=IDA, GO:0048096=TAS, GO:0030521=IDA, GO:0030520=IDA} androgen receptor signaling pathway, chromatin organization, chromatin remodeling, chromatin-mediated maintenance of transcription, glucocorticoid receptor signaling pathway, intracellular estrogen receptor signaling pathway, nervous system development, nucleosome disassembly, nucleosome mobilization, positive regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent SWI/SNF complex, nBAF complex, npBAF complex, nuclear chromatin, nucleolus, nucleus DNA binding, ligand-dependent nuclear receptor binding, protein binding, transcription coactivator activity Human Ensembl:ENSMUSP00000101517 ARID1B HPA UniProtKB {GO:0016514=PMID:11734557, GO:0003713=PMID:11734557, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0048096=PMID:11734557, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0007399=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q8NFD5 AT-rich interactive domain-containing protein 1B protein 20101115 {GO:0016514=IDA, GO:0003713=NAS, GO:0005730=IDA, GO:0005634=IDA, GO:0048096=NAS, GO:0003677=IEA, GO:0006351=IEA, GO:0007399=IEA, GO:0043231=IDA} chromatin-mediated maintenance of transcription, nervous system development, transcription, DNA-dependent SWI/SNF complex, intracellular membrane-bounded organelle, nucleolus, nucleus DNA binding, transcription coactivator activity Human ARID2 BHF-UCL UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0006337=PMID:8895581, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q68CP9 AT-rich interactive domain-containing protein 2 protein 20110811 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0006337=IDA, GO:0003677=IEA, GO:0006351=IEA, GO:0016568=IEA} chromatin modification, nucleosome disassembly, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human ARID3A MGI UniProtKB {GO:0006355=GO_REF:0000029, GO:0005737=GO_REF:0000039, GO:0003700=GO_REF:0000029, GO:0045944=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0045121=PMID:21955986, GO:0005634=GO_REF:0000029, GO:0003677=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q99856 AT-rich interactive domain-containing protein 3A protein 20120319 {GO:0006355=NAS, GO:0005737=IEA, GO:0003700=NAS, GO:0045944=IEA, GO:0003682=IEA, GO:0045121=IDA, GO:0005634=NAS, GO:0003677=IEA, GO:0042803=IEA, GO:0006351=IEA} positive regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, membrane raft, nucleus DNA binding, chromatin binding, protein homodimerization activity, sequence-specific DNA binding transcription factor activity Human ARID3B UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0006355=GO_REF:0000037, GO:0005634=PMID:10446990, GO:0003677=PMID:10446990, GO:0006351=GO_REF:0000037} Q8IVW6 AT-rich interactive domain-containing protein 3B protein 20070906 {GO:0008150=ND, GO:0006355=IEA, GO:0005634=NAS, GO:0003677=NAS, GO:0006351=IEA} biological_process, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding Human ARID4A GDB UniProtKB {GO:0003700=PMID:8414517, GO:0006366=PMID:8414517, GO:0017053=PMID:11283269, GO:0005634=PMID:11283269, GO:0045892=PMID:12724404, GO:0003677=GO_REF:0000002} P29374 AT-rich interactive domain-containing protein 4A protein 20050428 {GO:0003700=TAS, GO:0006366=TAS, GO:0017053=IDA, GO:0005634=IDA, GO:0045892=IDA, GO:0003677=IEA} negative regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter nucleus, transcriptional repressor complex DNA binding, sequence-specific DNA binding transcription factor activity Human ARID4B IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000039, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q4LE39 AT-rich interactive domain-containing protein 4B protein 20130415 {GO:0005515=IPI, GO:0003674=ND, GO:0008150=ND, GO:0005737=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0005575=ND, GO:0003677=IEA, GO:0006351=IEA} biological_process, regulation of transcription, DNA-dependent, transcription, DNA-dependent cellular_component, cytoplasm, nucleus DNA binding, molecular_function, protein binding Human UniProtKB:P14921 ARID5A HPA UniProtKB {GO:0005515=PMID:23275563, GO:0005667=GO_REF:0000019, GO:0002062=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0045892=PMID:15640446, GO:0035066=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0008134=GO_REF:0000019} Q03989 AT-rich interactive domain-containing protein 5A protein 20100326 {GO:0005515=IPI, GO:0005667=IEA, GO:0002062=IEA, GO:0045944=IEA, GO:0003682=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0045892=TAS, GO:0035066=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0008134=IEA} chondrocyte differentiation, negative regulation of transcription, DNA-dependent, positive regulation of histone acetylation, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleolus, nucleus, transcription factor complex DNA binding, chromatin binding, protein binding, transcription factor binding Human ARID5B GDB UniProtKB {GO:0005515=PMID:21532585, GO:0030325=GO_REF:0000019, GO:0044212=PMID:21532585, GO:0048705=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0009791=GO_REF:0000019, GO:0048644=GO_REF:0000019, GO:0010761=GO_REF:0000019, GO:0051091=PMID:21532585, GO:0035264=GO_REF:0000019, GO:0045444=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:0048468=GO_REF:0000019, GO:0001822=GO_REF:0000019, GO:0003713=PMID:21532585, GO:0003677=PMID:10329386, GO:0006351=GO_REF:0000037, GO:0001889=PMID:21532585, GO:0008585=GO_REF:0000019, GO:0060325=GO_REF:0000019, GO:0060613=GO_REF:0000019, GO:0048008=GO_REF:0000019, GO:0060612=GO_REF:0000024, GO:0045892=PMID:15640446, GO:0008584=GO_REF:0000019} Q14865 AT-rich interactive domain-containing protein 5B protein 20050428 {GO:0005515=IPI, GO:0030325=IEA, GO:0044212=IDA, GO:0048705=IEA, GO:0005634=IEA, GO:0009791=IEA, GO:0048644=IEA, GO:0010761=IEA, GO:0051091=IDA, GO:0035264=IEA, GO:0045444=IEA, GO:0060021=IEA, GO:0048468=IEA, GO:0001822=IEA, GO:0003713=IDA, GO:0003677=IDA, GO:0006351=IEA, GO:0001889=TAS, GO:0008585=IEA, GO:0060325=IEA, GO:0060613=IEA, GO:0048008=IEA, GO:0060612=ISS, GO:0045892=TAS, GO:0008584=IEA} adipose tissue development, adrenal gland development, cell development, face morphogenesis, fat cell differentiation, fat pad development, female gonad development, fibroblast migration, kidney development, liver development, male gonad development, multicellular organism growth, muscle organ morphogenesis, negative regulation of transcription, DNA-dependent, palate development, platelet-derived growth factor receptor signaling pathway, positive regulation of sequence-specific DNA binding transcription factor activity, post-embryonic development, skeletal system morphogenesis, transcription, DNA-dependent nucleus DNA binding, protein binding, transcription coactivator activity, transcription regulatory region DNA binding Human ARIH1 Reactome UniProtKB {GO:0005515=PMID:14623119, GO:0006511=PMID:10521492, GO:0005737=PMID:11278816, GO:0004842=PMID:21532592, GO:0016567=PMID:21532592, GO:0019787=PMID:10521492, GO:0019221=Reactome:REACT_25229, GO:0000151=PMID:10521492, GO:0008270=PMID:15236971, GO:0031625=PMID:21532592, GO:0005829=Reactome:REACT_116157} Q9Y4X5 E3 ubiquitin-protein ligase ARIH1 protein 20130301 {GO:0005515=IPI, GO:0006511=TAS, GO:0005737=IDA, GO:0004842=IDA, GO:0016567=IDA, GO:0019787=TAS, GO:0019221=TAS, GO:0000151=TAS, GO:0008270=IDA, GO:0031625=IPI, GO:0005829=TAS} cytokine-mediated signaling pathway, protein ubiquitination, ubiquitin-dependent protein catabolic process cytoplasm, cytosol, ubiquitin ligase complex protein binding, small conjugating protein ligase activity, ubiquitin protein ligase binding, ubiquitin-protein ligase activity, zinc ion binding Human ARIH2 IntAct UniProtKB {GO:0000209=PMID:19340006, GO:0005515=PMID:19549727, GO:0006511=GO_REF:0000019, GO:0004842=PMID:16118314, GO:0007275=PMID:10422847, GO:0005634=PMID:16118314, GO:0003676=GO_REF:0000002, GO:0048588=PMID:19340006, GO:0005737=PMID:19340006, GO:0070534=PMID:19340006, GO:0071425=PMID:16118314, GO:0042787=PMID:16118314, GO:0008270=GO_REF:0000002, GO:0070936=PMID:19340006} O95376 E3 ubiquitin-protein ligase ARIH2 protein 20130415 {GO:0000209=IDA, GO:0005515=IPI, GO:0006511=IEA, GO:0004842=IDA, GO:0007275=TAS, GO:0005634=IDA, GO:0003676=IEA, GO:0048588=IDA, GO:0005737=IDA, GO:0070534=IDA, GO:0071425=IDA, GO:0042787=IDA, GO:0008270=IEA, GO:0070936=IDA} developmental cell growth, hematopoietic stem cell proliferation, multicellular organismal development, protein K48-linked ubiquitination, protein K63-linked ubiquitination, protein polyubiquitination, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, ubiquitin-dependent protein catabolic process cytoplasm, nucleus nucleic acid binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:P68036 ARL1 LIFEdb UniProtKB {GO:0005802=GO_REF:0000024, GO:0031584=PMID:9624189, GO:0005794=GO_REF:0000054, GO:0007264=GO_REF:0000002, GO:0019904=PMID:14580338, GO:0003924=PMID:8798635, GO:0005525=PMID:9624189, GO:0046872=GO_REF:0000037, GO:0006184=PMID:8798635, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000024, GO:0000139=GO_REF:0000039, GO:0034067=PMID:19224922, GO:0007030=GO_REF:0000024, GO:0042147=PMID:19224922, GO:0048193=GO_REF:0000019, GO:0009404=PMID:9624189, GO:0008047=PMID:9624189} P40616 ADP-ribosylation factor-like protein 1 protein 20100607 {GO:0005802=ISS, GO:0031584=IDA, GO:0005794=IDA, GO:0007264=IEA, GO:0019904=IPI, GO:0003924=IDA, GO:0005525=IDA, GO:0046872=IEA, GO:0006184=IDA, GO:0005622=IEA, GO:0005737=ISS, GO:0000139=IEA, GO:0034067=IMP, GO:0007030=ISS, GO:0042147=IMP, GO:0048193=IEA, GO:0009404=IDA, GO:0008047=IDA} GTP catabolic process, Golgi organization, Golgi vesicle transport, activation of phospholipase D activity, protein localization to Golgi apparatus, retrograde transport, endosome to Golgi, small GTPase mediated signal transduction, toxin metabolic process Golgi apparatus, Golgi membrane, cytoplasm, intracellular, trans-Golgi network GTP binding, GTPase activity, enzyme activator activity, metal ion binding, protein domain specific binding Human ARL10 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q8N8L6 ADP-ribosylation factor-like protein 10 protein 20130413 {GO:0005622=IEA, GO:0007264=IEA, GO:0005525=IEA} small GTPase mediated signal transduction intracellular GTP binding Human UniProtKB-KW:KW-0342 ARL11 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0005622=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q969Q4 ADP-ribosylation factor-like protein 11 protein 20130415 {GO:0005515=IPI, GO:0005622=IEA, GO:0007264=IEA, GO:0005525=IEA} small GTPase mediated signal transduction intracellular GTP binding, protein binding Human UniProtKB:Q15645 ARL13A UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q5H913 ADP-ribosylation factor-like protein 13A protein 20130413 {GO:0005622=IEA, GO:0007264=IEA, GO:0005525=IEA} small GTPase mediated signal transduction intracellular GTP binding Human UniProtKB-KW:KW-0342 ARL13B UniProtKB UniProtKB {GO:0005515=PMID:20643351, GO:0005929=GO_REF:0000019, GO:0007368=GO_REF:0000019, GO:0007264=GO_REF:0000002, GO:0009953=GO_REF:0000019, GO:0005525=GO_REF:0000037} Q3SXY8 ADP-ribosylation factor-like protein 13B protein 20120708 {GO:0005515=IPI, GO:0005929=IEA, GO:0007368=IEA, GO:0007264=IEA, GO:0009953=IEA, GO:0005525=IEA} determination of left/right symmetry, dorsal/ventral pattern formation, small GTPase mediated signal transduction cilium GTP binding, protein binding Human UniProtKB:Q9D9W1 ARL14 IntAct UniProtKB {GO:0005515=PMID:21458045, GO:0007264=GO_REF:0000002, GO:0016023=GO_REF:0000039, GO:0005525=GO_REF:0000037} Q8N4G2 ADP-ribosylation factor-like protein 14 protein 20130415 {GO:0005515=IPI, GO:0007264=IEA, GO:0016023=IEA, GO:0005525=IEA} small GTPase mediated signal transduction cytoplasmic membrane-bounded vesicle GTP binding, protein binding Human UniProtKB:Q8N8R7 ARL15 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q9NXU5 ADP-ribosylation factor-like protein 15 protein 20130413 {GO:0005622=IEA, GO:0007264=IEA, GO:0005525=IEA} small GTPase mediated signal transduction intracellular GTP binding Human UniProtKB-KW:KW-0342 ARL16 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q0P5N6 ADP-ribosylation factor-like protein 16 protein 20130413 {GO:0005622=IEA, GO:0007264=IEA, GO:0005525=IEA} small GTPase mediated signal transduction intracellular GTP binding Human UniProtKB-KW:KW-0342 ARL17A UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0005794=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0016192=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0005525=GO_REF:0000037} Q8IVW1 ADP-ribosylation factor-like protein 17 protein 20130413 {GO:0005622=IEA, GO:0005794=IEA, GO:0007264=IEA, GO:0016192=IEA, GO:0015031=IEA, GO:0005525=IEA} protein transport, small GTPase mediated signal transduction, vesicle-mediated transport Golgi apparatus, intracellular GTP binding Human UniProtKB-SubCell:SL-0132 ARL17B UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0005525=GO_REF:0000038} I3L3L1 ADP-ribosylation factor-like protein 17 protein 20130413 {GO:0005622=IEA, GO:0007264=IEA, GO:0005525=IEA} small GTPase mediated signal transduction intracellular GTP binding Human UniProtKB-KW:KW-0342 ARL2 GOC UniProtKB {GO:0005515=PMID:19368893, GO:0031116=PMID:20740604, GO:0005813=PMID:16525022, GO:0007264=GO_REF:0000002, GO:0010811=GO_REF:0000024, GO:0031113=PMID:16525022, GO:0003924=PMID:10831612, GO:0005634=PMID:18234692, GO:0005525=PMID:10831612, GO:0016328=GO_REF:0000024, GO:0006184=PMID:10831612, GO:0051297=PMID:16525022, GO:0005622=GO_REF:0000002, GO:0005758=PMID:11809823, GO:0007049=GO_REF:0000037, GO:0070830=GO_REF:0000024, GO:0007021=PMID:10831612, GO:0051457=PMID:18234692, GO:0005095=PMID:10831612, GO:0019003=GO_REF:0000019, GO:0034260=PMID:10831612} P36404 ADP-ribosylation factor-like protein 2 protein 20130413 {GO:0005515=IPI, GO:0031116=IDA, GO:0005813=IDA, GO:0007264=IEA, GO:0010811=ISS, GO:0031113=IMP, GO:0003924=IMP, GO:0005634=IDA, GO:0005525=IMP, GO:0016328=ISS, GO:0006184=IMP, GO:0051297=IMP, GO:0005622=IEA, GO:0005758=IDA, GO:0007049=IEA, GO:0070830=ISS, GO:0007021=TAS, GO:0051457=IDA, GO:0005095=TAS, GO:0019003=IEA, GO:0034260=IDA} GTP catabolic process, cell cycle, centrosome organization, maintenance of protein location in nucleus, negative regulation of GTPase activity, positive regulation of cell-substrate adhesion, positive regulation of microtubule polymerization, regulation of microtubule polymerization, small GTPase mediated signal transduction, tight junction assembly, tubulin complex assembly centrosome, intracellular, lateral plasma membrane, mitochondrial intermembrane space, nucleus GDP binding, GTP binding, GTPase activity, GTPase inhibitor activity, protein binding Human ARL2BP PINC UniProtKB {GO:0005515=PMID:19368893, GO:0007165=PMID:10488091, GO:0005758=PMID:11809823, GO:0005083=PMID:10488091, GO:0005813=PMID:16525022, GO:0051457=PMID:18234692, GO:0042517=PMID:18234692, GO:0003713=PMID:18234692, GO:0005819=GO_REF:0000039, GO:0030496=PMID:16525022, GO:0005634=GO_REF:0000039} Q9Y2Y0 ADP-ribosylation factor-like protein 2-binding protein protein 20030904 {GO:0005515=IPI, GO:0007165=TAS, GO:0005758=IDA, GO:0005083=TAS, GO:0005813=IDA, GO:0051457=IMP, GO:0042517=IMP, GO:0003713=IMP, GO:0005819=IEA, GO:0030496=IDA, GO:0005634=IEA} maintenance of protein location in nucleus, positive regulation of tyrosine phosphorylation of Stat3 protein, signal transduction centrosome, midbody, mitochondrial intermembrane space, nucleus, spindle protein binding, small GTPase regulator activity, transcription coactivator activity Human ARL3 HPA UniProtKB {GO:0005515=PMID:22085962, GO:0008017=PMID:12417528, GO:0005881=PMID:12417528, GO:0042461=GO_REF:0000024, GO:0005886=GO_REF:0000052, GO:0007264=PMID:22085962, GO:0003924=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0015031=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0000910=PMID:16525022, GO:0005737=GO_REF:0000052, GO:0042073=GO_REF:0000019, GO:0005876=PMID:16525022, GO:0005813=PMID:16525022, GO:0005794=GO_REF:0000052, GO:0001822=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0030496=PMID:16525022, GO:0072372=PMID:16525022, GO:0005525=PMID:22085962, GO:0007049=GO_REF:0000037, GO:0000139=GO_REF:0000039, GO:0060271=PMID:22085962, GO:0032391=PMID:12417528, GO:0019003=PMID:18588884} P36405 ADP-ribosylation factor-like protein 3 protein 20110516 {GO:0005515=IPI, GO:0008017=IDA, GO:0005881=IDA, GO:0042461=ISS, GO:0005886=IDA, GO:0007264=IDA, GO:0003924=IEA, GO:0005634=IDA, GO:0015031=IEA, GO:0046872=IEA, GO:0000910=IMP, GO:0005737=IDA, GO:0042073=IEA, GO:0005876=IDA, GO:0005813=IDA, GO:0005794=IDA, GO:0001822=ISS, GO:0005730=IDA, GO:0030496=IDA, GO:0072372=IDA, GO:0005525=IDA, GO:0007049=IEA, GO:0000139=IEA, GO:0060271=IMP, GO:0032391=IDA, GO:0019003=IDA} cell cycle, cilium morphogenesis, cytokinesis, intraflagellar transport, kidney development, photoreceptor cell development, protein transport, small GTPase mediated signal transduction Golgi apparatus, Golgi membrane, centrosome, cytoplasm, cytoplasmic microtubule, midbody, nucleolus, nucleus, photoreceptor connecting cilium, plasma membrane, primary cilium, spindle microtubule GDP binding, GTP binding, GTPase activity, metal ion binding, microtubule binding, protein binding Human ARL4A UniProtKB UniProtKB {GO:0005515=PMID:17398095, GO:0005737=GO_REF:0000039, GO:0005886=PMID:17398095, GO:0007264=GO_REF:0000002, GO:0050873=GO_REF:0000019, GO:0005730=PMID:10980193, GO:0005634=PMID:10980193, GO:0005525=PMID:10980193} P40617 ADP-ribosylation factor-like protein 4A protein 20101220 {GO:0005515=IPI, GO:0005737=IEA, GO:0005886=IDA, GO:0007264=IEA, GO:0050873=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005525=IDA} brown fat cell differentiation, small GTPase mediated signal transduction cytoplasm, nucleolus, nucleus, plasma membrane GTP binding, protein binding Human UniProtKB:Q99418 ARL4C GOC UniProtKB {GO:0006184=PMID:10462049, GO:0005515=PMID:17398095, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0043014=PMID:19409876, GO:0007264=GO_REF:0000002, GO:0032456=PMID:19409876, GO:0003924=PMID:10462049, GO:0005634=PMID:10462049, GO:0030175=GO_REF:0000039, GO:0005525=GO_REF:0000037} P56559 ADP-ribosylation factor-like protein 4C protein 20130413 {GO:0006184=TAS, GO:0005515=IPI, GO:0005737=IDA, GO:0005886=IDA, GO:0043014=IDA, GO:0007264=IEA, GO:0032456=IDA, GO:0003924=TAS, GO:0005634=TAS, GO:0030175=IEA, GO:0005525=IEA} GTP catabolic process, endocytic recycling, small GTPase mediated signal transduction cytoplasm, filopodium, nucleus, plasma membrane GTP binding, GTPase activity, alpha-tubulin binding, protein binding Human ARL4D GOC UniProtKB {GO:0006184=PMID:7590735, GO:0005515=PMID:17398095, GO:0005737=PMID:17398095, GO:0009306=PMID:7590735, GO:0005886=PMID:17398095, GO:0007264=GO_REF:0000002, GO:0003924=PMID:7590735, GO:0005730=GO_REF:0000039, GO:0005525=GO_REF:0000037} P49703 ADP-ribosylation factor-like protein 4D protein 20130413 {GO:0006184=TAS, GO:0005515=IPI, GO:0005737=IDA, GO:0009306=TAS, GO:0005886=IDA, GO:0007264=IEA, GO:0003924=TAS, GO:0005730=IEA, GO:0005525=IEA} GTP catabolic process, protein secretion, small GTPase mediated signal transduction cytoplasm, nucleolus, plasma membrane GTP binding, GTPase activity, protein binding Human ARL5A UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q9Y689 ADP-ribosylation factor-like protein 5A protein 20130413 {GO:0005622=IEA, GO:0007264=IEA, GO:0005525=IEA} small GTPase mediated signal transduction intracellular GTP binding Human UniProtKB-KW:KW-0342 ARL5B UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q96KC2 ADP-ribosylation factor-like protein 5B protein 20130413 {GO:0005622=IEA, GO:0007264=IEA, GO:0005525=IEA} small GTPase mediated signal transduction intracellular GTP binding Human UniProtKB-KW:KW-0342 ARL6 BHF-UCL UniProtKB {GO:0007368=GO_REF:0000024, GO:0051258=GO_REF:0000024, GO:0060170=GO_REF:0000039, GO:0034464=GO_REF:0000024, GO:0007264=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0035085=GO_REF:0000024, GO:0032402=GO_REF:0000024, GO:0030117=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0042384=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0005543=GO_REF:0000024, GO:0016020=GO_REF:0000024, GO:0006612=GO_REF:0000024, GO:0005879=GO_REF:0000024, GO:0045444=GO_REF:0000019, GO:0005932=GO_REF:0000039, GO:0016055=PMID:20207729, GO:0007601=GO_REF:0000037} Q9H0F7 ADP-ribosylation factor-like protein 6 protein 20080517 {GO:0007368=ISS, GO:0051258=ISS, GO:0060170=IEA, GO:0034464=ISS, GO:0007264=IEA, GO:0005525=IEA, GO:0035085=ISS, GO:0032402=ISS, GO:0030117=ISS, GO:0046872=IEA, GO:0042384=ISS, GO:0005737=ISS, GO:0005543=ISS, GO:0016020=ISS, GO:0006612=ISS, GO:0005879=ISS, GO:0045444=IEA, GO:0005932=IEA, GO:0016055=IMP, GO:0007601=IEA} Wnt receptor signaling pathway, cilium assembly, determination of left/right symmetry, fat cell differentiation, melanosome transport, protein polymerization, protein targeting to membrane, small GTPase mediated signal transduction, visual perception BBSome, axonemal microtubule, cilium axoneme, cilium membrane, cytoplasm, membrane, membrane coat, microtubule basal body GTP binding, metal ion binding, phospholipid binding Human UniProtKB:Q5M9P8 ARL6IP1 HPA UniProtKB {GO:0005515=PMID:19060904, GO:0005784=GO_REF:0000019, GO:0005783=GO_REF:0000052, GO:0006613=GO_REF:0000019, GO:0016021=GO_REF:0000019, GO:0005829=GO_REF:0000019} Q15041 ADP-ribosylation factor-like protein 6-interacting protein 1 protein 20111111 {GO:0005515=IPI, GO:0005784=IEA, GO:0005783=IDA, GO:0006613=IEA, GO:0016021=IEA, GO:0005829=IEA} cotranslational protein targeting to membrane Sec61 translocon complex, cytosol, endoplasmic reticulum, integral to membrane protein binding Human ARL6IP4 IntAct UniProtKB {GO:0005515=PMID:20098747, GO:0008380=PMID:10708573, GO:0005634=PMID:10708573} Q66PJ3 ADP-ribosylation factor-like protein 6-interacting protein 4 protein 20130415 {GO:0005515=IPI, GO:0008380=TAS, GO:0005634=TAS} RNA splicing nucleus protein binding Human UniProtKB:Q9Y6K9 ARL6IP5 HPA UniProtKB {GO:0015813=GO_REF:0000024, GO:0005737=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0005783=GO_REF:0000052, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0008022=GO_REF:0000019, GO:0051051=GO_REF:0000019} O75915 PRA1 family protein 3 protein 20101115 {GO:0015813=ISS, GO:0005737=IEA, GO:0016020=IEA, GO:0005783=IDA, GO:0005789=IEA, GO:0016021=IEA, GO:0008022=IEA, GO:0051051=IEA} L-glutamate transport, negative regulation of transport cytoplasm, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, membrane protein C-terminus binding Human ARL6IP6 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8N6S5 ADP-ribosylation factor-like protein 6-interacting protein 6 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 ARL8A GOC UniProtKB {GO:0007264=GO_REF:0000002, GO:0043014=PMID:15331635, GO:0003924=PMID:15331635, GO:0048487=PMID:15331635, GO:0030496=PMID:15331635, GO:0005765=GO_REF:0000039, GO:0005525=PMID:15331635, GO:0051233=PMID:15331635, GO:0006184=PMID:15331635, GO:0007067=GO_REF:0000037, GO:0005737=PMID:15331635, GO:0007059=PMID:14871887, GO:0031902=GO_REF:0000039, GO:0051301=GO_REF:0000037} Q96BM9 ADP-ribosylation factor-like protein 8A protein 20130413 {GO:0007264=IEA, GO:0043014=ISS, GO:0003924=NAS, GO:0048487=ISS, GO:0030496=IDA, GO:0005765=IEA, GO:0005525=IDA, GO:0051233=IDA, GO:0006184=NAS, GO:0007067=IEA, GO:0005737=IDA, GO:0007059=ISS, GO:0031902=IEA, GO:0051301=IEA} GTP catabolic process, cell division, chromosome segregation, mitosis, small GTPase mediated signal transduction cytoplasm, late endosome membrane, lysosomal membrane, midbody, spindle midzone GTP binding, GTPase activity, alpha-tubulin binding, beta-tubulin binding Human ARL8B GOC UniProtKB {GO:0007264=GO_REF:0000002, GO:0043014=PMID:15331635, GO:0048487=PMID:15331635, GO:0003924=PMID:15331635, GO:0030496=PMID:15331635, GO:0005525=PMID:15331635, GO:0005765=GO_REF:0000039, GO:0051233=PMID:15331635, GO:0006184=PMID:15331635, GO:0005622=GO_REF:0000002, GO:0007049=GO_REF:0000037, GO:0005737=PMID:15331635, GO:0007059=PMID:14871887, GO:0031902=GO_REF:0000039, GO:0019003=PMID:15331635, GO:0051301=GO_REF:0000037} Q9NVJ2 ADP-ribosylation factor-like protein 8B protein 20130413 {GO:0007264=IEA, GO:0043014=IDA, GO:0048487=IDA, GO:0003924=NAS, GO:0030496=IDA, GO:0005525=IDA, GO:0005765=IEA, GO:0051233=IDA, GO:0006184=NAS, GO:0005622=IEA, GO:0007049=IEA, GO:0005737=IDA, GO:0007059=IMP, GO:0031902=IEA, GO:0019003=IDA, GO:0051301=IEA} GTP catabolic process, cell cycle, cell division, chromosome segregation, small GTPase mediated signal transduction cytoplasm, intracellular, late endosome membrane, lysosomal membrane, midbody, spindle midzone GDP binding, GTP binding, GTPase activity, alpha-tubulin binding, beta-tubulin binding Human ARMC1 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0046872=GO_REF:0000002, GO:0030001=GO_REF:0000002} Q9NVT9 Armadillo repeat-containing protein 1 protein 20130413 {GO:0005739=IEA, GO:0046872=IEA, GO:0030001=IEA} metal ion transport mitochondrion metal ion binding Human Ensembl:ENSMUSP00000029125 ARMC10 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0040008=GO_REF:0000037} Q8N2F6 Armadillo repeat-containing protein 10 protein 20130413 {GO:0005739=IEA, GO:0005789=IEA, GO:0016021=IEA, GO:0040008=IEA} regulation of growth endoplasmic reticulum membrane, integral to membrane, mitochondrion Human UniProtKB-SubCell:SL-0097 ARMC4 null null {} null null null null {} null null null ARMC5 null null {} null null null null {} null null null ARMC6 null null {} null null null null {} null null null ARMC7 null null {} null null null null {} null null null ARMC8 null null {} null null null null {} null null null ARMC9 null null {} null null null null {} null null null ARMCX1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9P291 Armadillo repeat-containing X-linked protein 1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 ARMCX2 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q7L311 Armadillo repeat-containing X-linked protein 2 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 ARMCX3 ENSEMBL UniProtKB {GO:0045944=GO_REF:0000019, GO:0034613=GO_REF:0000019, GO:0031307=GO_REF:0000019} Q9UH62 Armadillo repeat-containing X-linked protein 3 protein 20130413 {GO:0045944=IEA, GO:0034613=IEA, GO:0031307=IEA} cellular protein localization, positive regulation of transcription from RNA polymerase II promoter integral to mitochondrial outer membrane Human Ensembl:ENSMUSP00000084097 ARMCX5 null null {} null null null null {} null null null ARNT BHF-UCL UniProtKB {GO:0005515=PMID:21620138, GO:0030949=PMID:8756616, GO:0003700=PMID:1317062, GO:0003705=PMID:7539918, GO:0061418=Reactome:REACT_120815, GO:0005634=GO_REF:0000052, GO:0030154=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0046886=PMID:1448077, GO:0045944=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0033235=GO_REF:0000019, GO:0004874=GO_REF:0000019, GO:0042789=PMID:7539918, GO:0004871=GO_REF:0000002, GO:0045821=PMID:8089148, GO:0005667=GO_REF:0000002, GO:0001666=PMID:8756616, GO:0046982=PMID:9079689, GO:0003713=GO_REF:0000019, GO:0001892=GO_REF:0000019, GO:0071456=Reactome:REACT_121311, GO:0043619=PMID:8089148, GO:0033554=Reactome:REACT_120956, GO:0010575=PMID:8756616, GO:0003677=GO_REF:0000038, GO:0006351=PMID:1317062, GO:0043565=PMID:7539918, GO:0001938=PMID:8756616, GO:0045648=PMID:1448077, GO:0005654=Reactome:REACT_121202, GO:0017162=PMID:9079689, GO:0045893=PMID:8089148, GO:0008134=PMID:10692439} P27540 Aryl hydrocarbon receptor nuclear translocator protein 20110609 {GO:0005515=IPI, GO:0030949=IC, GO:0003700=TAS, GO:0003705=IDA, GO:0061418=TAS, GO:0005634=IDA, GO:0030154=IEA, GO:0005737=IEA, GO:0046886=IDA, GO:0045944=IEA, GO:0046983=IEA, GO:0033235=IEA, GO:0004874=IEA, GO:0042789=IC, GO:0004871=IEA, GO:0045821=IC, GO:0005667=IEA, GO:0001666=IDA, GO:0046982=IPI, GO:0003713=IEA, GO:0001892=IEA, GO:0071456=TAS, GO:0043619=IDA, GO:0033554=TAS, GO:0010575=IDA, GO:0003677=IEA, GO:0006351=TAS, GO:0043565=IDA, GO:0001938=IC, GO:0045648=IC, GO:0005654=TAS, GO:0017162=IPI, GO:0045893=IDA, GO:0008134=IPI} cell differentiation, cellular response to hypoxia, cellular response to stress, embryonic placenta development, mRNA transcription from RNA polymerase II promoter, positive regulation of endothelial cell proliferation, positive regulation of erythrocyte differentiation, positive regulation of glycolysis, positive regulation of hormone biosynthetic process, positive regulation of protein sumoylation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of vascular endothelial growth factor receptor signaling pathway, positive regulation vascular endothelial growth factor production, regulation of transcription from RNA polymerase II promoter in response to hypoxia, regulation of transcription from RNA polymerase II promoter in response to oxidative stress, response to hypoxia, transcription, DNA-dependent cytoplasm, nucleoplasm, nucleus, transcription factor complex DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, aryl hydrocarbon receptor activity, aryl hydrocarbon receptor binding, protein binding, protein dimerization activity, protein heterodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, signal transducer activity, transcription coactivator activity, transcription factor binding Human UniProtKB:Q9Y5J3 ARNT2 MGI UniProtKB {GO:0001666=PMID:12239177, GO:0005667=GO_REF:0000019, GO:0006355=PMID:11782478, GO:0008284=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0003700=GO_REF:0000024, GO:0046982=PMID:12239177, GO:0005634=PMID:12239177, GO:0007417=GO_REF:0000024, GO:0001701=GO_REF:0000024, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0005737=GO_REF:0000002, GO:0045944=GO_REF:0000019, GO:0004871=GO_REF:0000002, GO:0017162=GO_REF:0000024, GO:0045893=GO_REF:0000024, GO:0032355=GO_REF:0000019} Q9HBZ2 Aryl hydrocarbon receptor nuclear translocator 2 protein 20031023 {GO:0001666=IDA, GO:0005667=IEA, GO:0006355=IDA, GO:0008284=IEA, GO:0043066=IEA, GO:0003700=ISS, GO:0046982=IPI, GO:0005634=IDA, GO:0007417=ISS, GO:0001701=ISS, GO:0003677=IEA, GO:0006351=IEA, GO:0005737=IEA, GO:0045944=IEA, GO:0004871=IEA, GO:0017162=ISS, GO:0045893=ISS, GO:0032355=IEA} central nervous system development, in utero embryonic development, negative regulation of apoptotic process, positive regulation of cell proliferation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, response to estradiol stimulus, response to hypoxia, transcription, DNA-dependent cytoplasm, nucleus, transcription factor complex DNA binding, aryl hydrocarbon receptor binding, protein heterodimerization activity, sequence-specific DNA binding transcription factor activity, signal transducer activity Human ARNTL BHF-UCL UniProtKB {GO:0005667=PMID:9576906, GO:0006355=GO_REF:0000024, GO:0003700=GO_REF:0000002, GO:0001190=GO_REF:0000019, GO:0042176=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0000982=GO_REF:0000024, GO:0051879=PMID:9079689, GO:0043425=GO_REF:0000019, GO:0003677=PMID:9576906, GO:0006351=GO_REF:0000038, GO:0032922=GO_REF:0000024, GO:0016604=GO_REF:0000019, GO:0005737=GO_REF:0000002, GO:0045944=PMID:20093779, GO:0046983=GO_REF:0000002, GO:0007623=PMID:9616112, GO:0017162=PMID:9079689, GO:0004871=GO_REF:0000002, GO:0000060=GO_REF:0000019} O00327 Aryl hydrocarbon receptor nuclear translocator-like protein 1 protein 20111105 {GO:0005667=IPI, GO:0006355=ISS, GO:0003700=IEA, GO:0001190=IEA, GO:0042176=IEA, GO:0046982=IEA, GO:0000982=ISS, GO:0051879=IDA, GO:0043425=IEA, GO:0003677=IGI, GO:0006351=IEA, GO:0032922=ISS, GO:0016604=IEA, GO:0005737=IEA, GO:0045944=IDA, GO:0046983=IEA, GO:0007623=TAS, GO:0017162=IPI, GO:0004871=IEA, GO:0000060=IEA} circadian regulation of gene expression, circadian rhythm, positive regulation of transcription from RNA polymerase II promoter, protein import into nucleus, translocation, regulation of protein catabolic process, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nuclear body, transcription factor complex DNA binding, Hsp90 protein binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription, aryl hydrocarbon receptor binding, bHLH transcription factor binding, protein dimerization activity, protein heterodimerization activity, sequence-specific DNA binding transcription factor activity, signal transducer activity Human UniProtKB:Q9WTL8 ARNTL2 BHF-UCL UniProtKB {GO:0005667=GO_REF:0000002, GO:0006355=PMID:11018023, GO:0003700=PMID:12055078, GO:0006357=PMID:12055078, GO:0000982=PMID:15147242, GO:0005634=PMID:12055078, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000038, GO:0005737=GO_REF:0000002, GO:0009649=PMID:11018023, GO:0045944=PMID:15147242, GO:0046983=GO_REF:0000002, GO:0007623=PMID:10864977, GO:0004871=GO_REF:0000002} Q8WYA1 Aryl hydrocarbon receptor nuclear translocator-like protein 2 protein 20111104 {GO:0005667=IEA, GO:0006355=NAS, GO:0003700=IDA, GO:0006357=IDA, GO:0000982=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA, GO:0005737=IEA, GO:0009649=NAS, GO:0045944=IDA, GO:0046983=IEA, GO:0007623=IDA, GO:0004871=IEA} circadian rhythm, entrainment of circadian clock, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus, transcription factor complex DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, protein dimerization activity, sequence-specific DNA binding transcription factor activity, signal transducer activity Human ARPC1A Reactome UniProtKB {GO:0030036=PMID:8978670, GO:0030833=GO_REF:0000002, GO:0045087=Reactome:REACT_6802, GO:0003779=GO_REF:0000037, GO:0015629=PMID:8978670, GO:0005856=GO_REF:0000002, GO:0038096=Reactome:REACT_160123, GO:0005829=Reactome:REACT_160291} Q92747 Actin-related protein 2/3 complex subunit 1A protein 20130213 {GO:0030036=TAS, GO:0030833=IEA, GO:0045087=TAS, GO:0003779=IEA, GO:0015629=TAS, GO:0005856=IEA, GO:0038096=TAS, GO:0005829=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, actin cytoskeleton organization, innate immune response, regulation of actin filament polymerization actin cytoskeleton, cytoskeleton, cytosol actin binding Human ARPC1B PINC UniProtKB {GO:0005737=GO_REF:0000037, GO:0030833=GO_REF:0000002, GO:0005885=PMID:9230079, GO:0005200=PMID:9230079, GO:0006928=PMID:9230079, GO:0003779=GO_REF:0000037, GO:0015629=PMID:9230079, GO:0005856=GO_REF:0000002} O15143 Actin-related protein 2/3 complex subunit 1B protein 20030904 {GO:0005737=IEA, GO:0030833=IEA, GO:0005885=TAS, GO:0005200=TAS, GO:0006928=TAS, GO:0003779=IEA, GO:0015629=TAS, GO:0005856=IEA} cellular component movement, regulation of actin filament polymerization Arp2/3 protein complex, actin cytoskeleton, cytoplasm, cytoskeleton actin binding, structural constituent of cytoskeleton Human ARPC2 HPA UniProtKB {GO:0005515=PMID:17350576, GO:0035650=GO_REF:0000019, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000019, GO:0005885=PMID:9230079, GO:0006928=PMID:9230079, GO:0071933=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0042995=GO_REF:0000039, GO:0015629=PMID:9230079, GO:0005829=Reactome:REACT_160291, GO:0005737=GO_REF:0000052, GO:0030833=GO_REF:0000002, GO:0030838=GO_REF:0000019, GO:1900026=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0005200=PMID:9230079, GO:0019894=GO_REF:0000019, GO:0005856=GO_REF:0000002, GO:0038096=Reactome:REACT_160123, GO:0005925=GO_REF:0000019, GO:0031252=GO_REF:0000019, GO:0005768=GO_REF:0000019} O15144 Actin-related protein 2/3 complex subunit 2 protein 20080818 {GO:0005515=IPI, GO:0035650=IEA, GO:0005794=IDA, GO:0005886=IEA, GO:0005885=TAS, GO:0006928=TAS, GO:0071933=IEA, GO:0003779=IEA, GO:0042995=IEA, GO:0015629=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0030833=IEA, GO:0030838=IEA, GO:1900026=IEA, GO:0045087=TAS, GO:0005200=TAS, GO:0019894=IEA, GO:0005856=IEA, GO:0038096=TAS, GO:0005925=IEA, GO:0031252=IEA, GO:0005768=IEA} Fc-gamma receptor signaling pathway involved in phagocytosis, cellular component movement, innate immune response, positive regulation of actin filament polymerization, positive regulation of substrate adhesion-dependent cell spreading, regulation of actin filament polymerization Arp2/3 protein complex, Golgi apparatus, actin cytoskeleton, cell leading edge, cell projection, cytoplasm, cytoskeleton, cytosol, endosome, focal adhesion, plasma membrane AP-1 adaptor complex binding, Arp2/3 complex binding, actin binding, kinesin binding, protein binding, structural constituent of cytoskeleton Human ARPC3 Reactome UniProtKB {GO:0005515=PMID:11162547, GO:0034314=GO_REF:0000002, GO:0005885=GO_REF:0000002, GO:0045087=Reactome:REACT_6802, GO:0005200=PMID:9230079, GO:0006928=PMID:9230079, GO:0003779=GO_REF:0000037, GO:0015629=PMID:9230079, GO:0038096=Reactome:REACT_160123, GO:0030027=GO_REF:0000019, GO:0005829=Reactome:REACT_160291} O15145 Actin-related protein 2/3 complex subunit 3 protein 20130213 {GO:0005515=IPI, GO:0034314=IEA, GO:0005885=IEA, GO:0045087=TAS, GO:0005200=TAS, GO:0006928=TAS, GO:0003779=IEA, GO:0015629=TAS, GO:0038096=TAS, GO:0030027=IEA, GO:0005829=TAS} Arp2/3 complex-mediated actin nucleation, Fc-gamma receptor signaling pathway involved in phagocytosis, cellular component movement, innate immune response Arp2/3 protein complex, actin cytoskeleton, cytosol, lamellipodium actin binding, protein binding, structural constituent of cytoskeleton Human ARPC4 Reactome UniProtKB {GO:0005515=PMID:11162547, GO:0034314=GO_REF:0000002, GO:0051015=PMID:11162547, GO:0005885=PMID:11162547, GO:0045087=Reactome:REACT_6802, GO:0030041=GO_REF:0000002, GO:0042995=GO_REF:0000039, GO:0030674=PMID:11162547, GO:0038096=Reactome:REACT_160123, GO:0005829=Reactome:REACT_160291, GO:0045010=PMID:11162547} P59998 Actin-related protein 2/3 complex subunit 4 protein 20130213 {GO:0005515=IPI, GO:0034314=IEA, GO:0051015=NAS, GO:0005885=IDA, GO:0045087=TAS, GO:0030041=IEA, GO:0042995=IEA, GO:0030674=IPI, GO:0038096=TAS, GO:0005829=TAS, GO:0045010=NAS} Arp2/3 complex-mediated actin nucleation, Fc-gamma receptor signaling pathway involved in phagocytosis, actin filament polymerization, actin nucleation, innate immune response Arp2/3 protein complex, cell projection, cytosol actin filament binding, protein binding, protein binding, bridging Human ARPC5 Reactome UniProtKB {GO:0005515=PMID:11162547, GO:0030036=PMID:9359840, GO:0005885=PMID:9230079, GO:0006928=PMID:9230079, GO:0003779=GO_REF:0000037, GO:0015629=PMID:9230079, GO:0030027=GO_REF:0000019, GO:0005829=Reactome:REACT_160291, GO:0005737=PMID:9359840, GO:0030833=GO_REF:0000002, GO:0045087=Reactome:REACT_6802, GO:0005200=PMID:9230079, GO:0005856=GO_REF:0000002, GO:0038096=Reactome:REACT_160123} O15511 Actin-related protein 2/3 complex subunit 5 protein 20130213 {GO:0005515=IPI, GO:0030036=TAS, GO:0005885=TAS, GO:0006928=TAS, GO:0003779=IEA, GO:0015629=TAS, GO:0030027=IEA, GO:0005829=TAS, GO:0005737=TAS, GO:0030833=IEA, GO:0045087=TAS, GO:0005200=TAS, GO:0005856=IEA, GO:0038096=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, actin cytoskeleton organization, cellular component movement, innate immune response, regulation of actin filament polymerization Arp2/3 protein complex, actin cytoskeleton, cytoplasm, cytoskeleton, cytosol, lamellipodium actin binding, protein binding, structural constituent of cytoskeleton Human ARPC5L UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0030833=GO_REF:0000002, GO:0003779=GO_REF:0000037, GO:0005856=GO_REF:0000039} Q9BPX5 Actin-related protein 2/3 complex subunit 5-like protein protein 20130413 {GO:0005737=IEA, GO:0030833=IEA, GO:0003779=IEA, GO:0005856=IEA} regulation of actin filament polymerization cytoplasm, cytoskeleton actin binding Human UniProtKB-SubCell:SL-0090 ARPP19 Reactome UniProtKB {GO:0004864=GO_REF:0000037, GO:0008601=GO_REF:0000024, GO:0045722=PMID:9653196, GO:0005102=PMID:9653196, GO:0015459=PMID:9653196, GO:0019212=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0007067=PMID:21164014, GO:0000088=Reactome:REACT_765, GO:0046326=PMID:9653196, GO:0000086=PMID:21164014, GO:0000087=Reactome:REACT_910, GO:0005654=Reactome:REACT_150326, GO:0000278=Reactome:REACT_152, GO:0051721=GO_REF:0000024, GO:0051301=GO_REF:0000037} P56211 cAMP-regulated phosphoprotein 19 protein 20130301 {GO:0004864=IEA, GO:0008601=ISS, GO:0045722=IDA, GO:0005102=IDA, GO:0015459=IDA, GO:0019212=ISS, GO:0005737=IEA, GO:0007067=IMP, GO:0000088=TAS, GO:0046326=NAS, GO:0000086=IMP, GO:0000087=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0051721=ISS, GO:0051301=IEA} G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, cell division, mitosis, mitotic cell cycle, mitotic prophase, positive regulation of gluconeogenesis, positive regulation of glucose import cytoplasm, nucleoplasm phosphatase inhibitor activity, potassium channel regulator activity, protein phosphatase 2A binding, protein phosphatase inhibitor activity, protein phosphatase type 2A regulator activity, receptor binding Human ARPP21 UniProtKB UniProtKB {GO:0034605=GO_REF:0000019, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005516=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0003676=GO_REF:0000002} Q9UBL0 cAMP-regulated phosphoprotein 21 protein 20061026 {GO:0034605=IEA, GO:0003674=ND, GO:0008150=ND, GO:0005516=IEA, GO:0005737=IEA, GO:0005575=ND, GO:0003676=IEA} biological_process, cellular response to heat cellular_component, cytoplasm calmodulin binding, molecular_function, nucleic acid binding Human ARR3 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0051219=GO_REF:0000019, GO:0007165=GO_REF:0000002, GO:0005737=PMID:8224247, GO:0045202=GO_REF:0000019, GO:0001932=GO_REF:0000019, GO:0002046=GO_REF:0000019, GO:0007601=GO_REF:0000037, GO:0006897=GO_REF:0000019, GO:0001750=GO_REF:0000019} P36575 Arrestin-C protein 20130415 {GO:0005515=IPI, GO:0051219=IEA, GO:0007165=IEA, GO:0005737=TAS, GO:0045202=IEA, GO:0001932=IEA, GO:0002046=IEA, GO:0007601=IEA, GO:0006897=IEA, GO:0001750=IEA} endocytosis, regulation of protein phosphorylation, signal transduction, visual perception cytoplasm, photoreceptor outer segment, synapse opsin binding, phosphoprotein binding, protein binding Human UniProtKB:Q96IT1 ARRB1 GOC UniProtKB {GO:0005515=PMID:21988832, GO:0032717=PMID:16378096, GO:0006366=PMID:16325578, GO:0044212=PMID:16325578, GO:0032715=PMID:16378096, GO:0005159=PMID:15878855, GO:0015031=GO_REF:0000037, GO:0005765=Reactome:REACT_19206, GO:0007219=Reactome:REACT_118859, GO:0031397=PMID:16378096, GO:0070374=PMID:10644702, GO:0000785=PMID:16325578, GO:0043027=GO_REF:0000019, GO:0031625=PMID:15878855, GO:0006892=Reactome:REACT_11235, GO:0031434=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0002031=PMID:10521508, GO:0043547=PMID:15611106, GO:0016044=Reactome:REACT_11123, GO:0008134=PMID:16325578, GO:0090240=PMID:16325578, GO:0016567=PMID:15878855, GO:0005886=PMID:9924018, GO:0035025=PMID:15611106, GO:0043149=PMID:15611106, GO:0005634=PMID:16325578, GO:0031701=PMID:15611106, GO:0035066=PMID:16325578, GO:0032092=GO_REF:0000019, GO:0031143=GO_REF:0000039, GO:0005829=Reactome:REACT_23958, GO:0005737=PMID:15611106, GO:0033138=GO_REF:0000019, GO:0045944=PMID:16325578, GO:0030659=Reactome:REACT_19255, GO:0004402=PMID:16325578, GO:0004857=PMID:2163110, GO:0035774=GO_REF:0000019, GO:0005834=PMID:10823817, GO:0032088=PMID:16378096, GO:0031410=PMID:15611106, GO:0007165=GO_REF:0000002, GO:0005905=GO_REF:0000039, GO:0000139=Reactome:REACT_19391, GO:0007596=Reactome:REACT_604, GO:0043161=PMID:15878855, GO:0007602=GO_REF:0000019, GO:0005096=PMID:15611106} P49407 Beta-arrestin-1 protein 20130413 {GO:0005515=IPI, GO:0032717=IDA, GO:0006366=IMP, GO:0044212=IMP, GO:0032715=IDA, GO:0005159=IPI, GO:0015031=IEA, GO:0005765=TAS, GO:0007219=TAS, GO:0031397=IDA, GO:0070374=IDA, GO:0000785=IDA, GO:0043027=IEA, GO:0031625=IPI, GO:0006892=TAS, GO:0031434=IEA, GO:0030168=TAS, GO:0002031=IMP, GO:0043547=IMP, GO:0016044=TAS, GO:0008134=IPI, GO:0090240=IMP, GO:0016567=IMP, GO:0005886=TAS, GO:0035025=IMP, GO:0043149=IMP, GO:0005634=IDA, GO:0031701=IPI, GO:0035066=IMP, GO:0032092=IEA, GO:0031143=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0033138=IEA, GO:0045944=IMP, GO:0030659=TAS, GO:0004402=IDA, GO:0004857=TAS, GO:0035774=IEA, GO:0005834=TAS, GO:0032088=IDA, GO:0031410=IDA, GO:0007165=IEA, GO:0005905=IEA, GO:0000139=TAS, GO:0007596=TAS, GO:0043161=IMP, GO:0007602=IEA, GO:0005096=IMP} G-protein coupled receptor internalization, Notch signaling pathway, blood coagulation, cellular membrane organization, negative regulation of NF-kappaB transcription factor activity, negative regulation of interleukin-6 production, negative regulation of interleukin-8 production, negative regulation of protein ubiquitination, phototransduction, platelet activation, positive regulation of ERK1 and ERK2 cascade, positive regulation of GTPase activity, positive regulation of Rho protein signal transduction, positive regulation of histone H4 acetylation, positive regulation of histone acetylation, positive regulation of insulin secretion involved in cellular response to glucose stimulus, positive regulation of peptidyl-serine phosphorylation, positive regulation of protein binding, positive regulation of transcription from RNA polymerase II promoter, post-Golgi vesicle-mediated transport, proteasomal ubiquitin-dependent protein catabolic process, protein transport, protein ubiquitination, signal transduction, stress fiber assembly, transcription from RNA polymerase II promoter Golgi membrane, chromatin, coated pit, cytoplasm, cytoplasmic vesicle, cytoplasmic vesicle membrane, cytosol, heterotrimeric G-protein complex, lysosomal membrane, nucleus, plasma membrane, pseudopodium GTPase activator activity, angiotensin receptor binding, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, enzyme inhibitor activity, histone acetyltransferase activity, insulin-like growth factor receptor binding, mitogen-activated protein kinase kinase binding, protein binding, transcription factor binding, transcription regulatory region DNA binding, ubiquitin protein ligase binding Human ARRB2 BHF-UCL UniProtKB {GO:0005515=PMID:19372219, GO:0006366=PMID:16820410, GO:0034122=GO_REF:0000019, GO:0032715=GO_REF:0000019, GO:0051928=GO_REF:0000019, GO:0032691=GO_REF:0000019, GO:0042699=GO_REF:0000019, GO:0050731=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0032403=GO_REF:0000019, GO:0031623=PMID:12958365, GO:0031762=GO_REF:0000019, GO:0007219=Reactome:REACT_118859, GO:0045211=GO_REF:0000019, GO:0031398=PMID:19372219, GO:0007179=PMID:12958365, GO:0031397=PMID:16378096, GO:0070374=PMID:12582207, GO:0034260=GO_REF:0000019, GO:0031625=PMID:19372219, GO:0051019=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0060765=PMID:19372219, GO:0030168=Reactome:REACT_798, GO:0032720=GO_REF:0000019, GO:0014069=GO_REF:0000019, GO:0002031=PMID:10644702, GO:0002032=PMID:12582207, GO:0031826=GO_REF:0000019, GO:0031691=GO_REF:0000019, GO:0031692=GO_REF:0000019, GO:0032226=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0051897=GO_REF:0000019, GO:0016567=PMID:15878855, GO:0005886=PMID:18604210, GO:0005634=PMID:16820410, GO:0031701=PMID:15611106, GO:0031702=GO_REF:0000019, GO:0005829=Reactome:REACT_23960, GO:0016323=GO_REF:0000019, GO:0071889=GO_REF:0000019, GO:0005737=PMID:12958365, GO:0031748=GO_REF:0000019, GO:0007628=GO_REF:0000019, GO:0050965=GO_REF:0000019, GO:0001664=PMID:10644702, GO:0005102=PMID:18604210, GO:0032088=PMID:16378096, GO:0031410=PMID:12958365, GO:0043422=GO_REF:0000019, GO:0007165=GO_REF:0000002, GO:0032947=PMID:19372219, GO:0005905=GO_REF:0000039, GO:0034392=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0060326=PMID:15635042, GO:0032695=GO_REF:0000019, GO:0045953=PMID:18604210, GO:0016023=GO_REF:0000039, GO:0043161=PMID:15878855, GO:0002092=GO_REF:0000019} P32121 Beta-arrestin-2 protein 20120316 {GO:0005515=IPI, GO:0006366=IDA, GO:0034122=IEA, GO:0032715=IEA, GO:0051928=IEA, GO:0032691=IEA, GO:0042699=IEA, GO:0050731=IEA, GO:0015031=IEA, GO:0032403=IEA, GO:0031623=IDA, GO:0031762=IEA, GO:0007219=TAS, GO:0045211=IEA, GO:0031398=IGI, GO:0007179=IDA, GO:0031397=IDA, GO:0070374=IMP, GO:0034260=IEA, GO:0031625=IPI, GO:0051019=IEA, GO:0019904=IEA, GO:0060765=IDA, GO:0030168=TAS, GO:0032720=IEA, GO:0014069=IEA, GO:0002031=IDA, GO:0002032=IMP, GO:0031826=IEA, GO:0031691=IEA, GO:0031692=IEA, GO:0032226=IEA, GO:0007420=IEA, GO:0051897=IEA, GO:0016567=IMP, GO:0005886=IDA, GO:0005634=IDA, GO:0031701=IPI, GO:0031702=IEA, GO:0005829=TAS, GO:0016323=IEA, GO:0071889=IEA, GO:0005737=IDA, GO:0031748=IEA, GO:0007628=IEA, GO:0050965=IEA, GO:0001664=IPI, GO:0005102=IPI, GO:0032088=IDA, GO:0031410=IDA, GO:0043422=IEA, GO:0007165=IEA, GO:0032947=IDA, GO:0005905=IEA, GO:0034392=IEA, GO:0007596=TAS, GO:0060326=IMP, GO:0032695=IEA, GO:0045953=IMP, GO:0016023=IEA, GO:0043161=IMP, GO:0002092=IEA} G-protein coupled receptor internalization, Notch signaling pathway, adult walking behavior, blood coagulation, brain development, cell chemotaxis, desensitization of G-protein coupled receptor protein signaling pathway by arrestin, detection of temperature stimulus involved in sensory perception of pain, follicle-stimulating hormone signaling pathway, negative regulation of GTPase activity, negative regulation of NF-kappaB transcription factor activity, negative regulation of interleukin-1 beta production, negative regulation of interleukin-12 production, negative regulation of interleukin-6 production, negative regulation of natural killer cell mediated cytotoxicity, negative regulation of protein ubiquitination, negative regulation of smooth muscle cell apoptotic process, negative regulation of toll-like receptor signaling pathway, negative regulation of tumor necrosis factor production, platelet activation, positive regulation of ERK1 and ERK2 cascade, positive regulation of calcium ion transport, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of protein kinase B signaling cascade, positive regulation of protein ubiquitination, positive regulation of receptor internalization, positive regulation of synaptic transmission, dopaminergic, proteasomal ubiquitin-dependent protein catabolic process, protein transport, protein ubiquitination, receptor internalization, regulation of androgen receptor signaling pathway, signal transduction, transcription from RNA polymerase II promoter, transforming growth factor beta receptor signaling pathway basolateral plasma membrane, coated pit, cytoplasm, cytoplasmic membrane-bounded vesicle, cytoplasmic vesicle, cytosol, nucleus, plasma membrane, postsynaptic density, postsynaptic membrane 14-3-3 protein binding, D1 dopamine receptor binding, G-protein coupled receptor binding, alpha-1A adrenergic receptor binding, alpha-1B adrenergic receptor binding, angiotensin receptor binding, follicle-stimulating hormone receptor binding, mitogen-activated protein kinase binding, protein binding, protein complex binding, protein complex scaffold, protein domain specific binding, protein kinase B binding, receptor binding, type 1 angiotensin receptor binding, type 2A serotonin receptor binding, ubiquitin protein ligase binding Human UniProtKB:Q08499-6 ARRDC1 null null {} null null null null {} null null null ARRDC2 InterPro UniProtKB {GO:0007165=GO_REF:0000002} Q8TBH0 Arrestin domain-containing protein 2 protein 20130413 {GO:0007165=IEA} signal transduction Human InterPro:IPR014752 ARRDC3 MGI UniProtKB {GO:0005737=GO_REF:0000039, GO:0001659=GO_REF:0000019, GO:0044252=GO_REF:0000019, GO:0031699=PMID:21982743, GO:0090327=GO_REF:0000019, GO:0060613=GO_REF:0000019, GO:0031651=GO_REF:0000019, GO:0071879=GO_REF:0000019} Q96B67 Arrestin domain-containing protein 3 protein 20121004 {GO:0005737=IEA, GO:0001659=IEA, GO:0044252=IEA, GO:0031699=IDA, GO:0090327=IEA, GO:0060613=IEA, GO:0031651=IEA, GO:0071879=IEA} fat pad development, negative regulation of heat generation, negative regulation of locomotion involved in locomotory behavior, negative regulation of multicellular organismal metabolic process, positive regulation of adrenergic receptor signaling pathway, temperature homeostasis cytoplasm beta-3 adrenergic receptor binding Human ARRDC4 null null {} null null null null {} null null null ARSA Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0006687=Reactome:REACT_116105, GO:0005509=PMID:12888274, GO:0005788=Reactome:REACT_121176, GO:0004065=PMID:2562955, GO:0044281=Reactome:REACT_111217, GO:0004098=Reactome:REACT_115556, GO:0008484=PMID:15962010, GO:0044267=Reactome:REACT_17015, GO:0005764=PMID:2562955, GO:0043687=Reactome:REACT_22161, GO:0043202=Reactome:REACT_121176} P15289 Arylsulfatase A protein 20110928 {GO:0006665=TAS, GO:0006687=TAS, GO:0005509=IDA, GO:0005788=TAS, GO:0004065=TAS, GO:0044281=TAS, GO:0004098=TAS, GO:0008484=IDA, GO:0044267=TAS, GO:0005764=TAS, GO:0043687=TAS, GO:0043202=TAS} cellular protein metabolic process, glycosphingolipid metabolic process, post-translational protein modification, small molecule metabolic process, sphingolipid metabolic process endoplasmic reticulum lumen, lysosomal lumen, lysosome arylsulfatase activity, calcium ion binding, cerebroside-sulfatase activity, sulfuric ester hydrolase activity Human ARSB Reactome UniProtKB {GO:0043627=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0005764=PMID:2303452, GO:0046872=GO_REF:0000037, GO:0005739=GO_REF:0000019, GO:0030207=Reactome:REACT_120888, GO:0003943=Reactome:REACT_121276, GO:0004065=GO_REF:0000019, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121315, GO:0009268=GO_REF:0000019, GO:0043202=Reactome:REACT_121276, GO:0005791=GO_REF:0000019, GO:0006665=Reactome:REACT_19323, GO:0005794=GO_REF:0000019, GO:0006687=Reactome:REACT_116105, GO:0007584=GO_REF:0000019, GO:0005975=Reactome:REACT_474, GO:0006914=GO_REF:0000019, GO:0007417=GO_REF:0000019, GO:0051597=GO_REF:0000019, GO:0005788=Reactome:REACT_121125, GO:0007041=PMID:2303452, GO:0007040=PMID:1718978, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} P15848 Arylsulfatase B protein 20110928 {GO:0043627=IEA, GO:0044281=TAS, GO:0005764=TAS, GO:0046872=IEA, GO:0005739=IEA, GO:0030207=TAS, GO:0003943=TAS, GO:0004065=IEA, GO:0030204=TAS, GO:0030203=TAS, GO:0009268=IEA, GO:0043202=TAS, GO:0005791=IEA, GO:0006665=TAS, GO:0005794=IEA, GO:0006687=TAS, GO:0007584=IEA, GO:0005975=TAS, GO:0006914=IEA, GO:0007417=IEA, GO:0051597=IEA, GO:0005788=TAS, GO:0007041=TAS, GO:0007040=TAS, GO:0044267=TAS, GO:0043687=TAS} autophagy, carbohydrate metabolic process, cellular protein metabolic process, central nervous system development, chondroitin sulfate catabolic process, chondroitin sulfate metabolic process, glycosaminoglycan metabolic process, glycosphingolipid metabolic process, lysosomal transport, lysosome organization, post-translational protein modification, response to estrogen stimulus, response to methylmercury, response to nutrient, response to pH, small molecule metabolic process, sphingolipid metabolic process Golgi apparatus, endoplasmic reticulum lumen, lysosomal lumen, lysosome, mitochondrion, rough endoplasmic reticulum N-acetylgalactosamine-4-sulfatase activity, arylsulfatase activity, metal ion binding Human ARSE Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0001501=PMID:7720070, GO:0006687=Reactome:REACT_116105, GO:0005795=GO_REF:0000039, GO:0005788=Reactome:REACT_121125, GO:0004065=PMID:9192838, GO:0044281=Reactome:REACT_111217, GO:0008484=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0046872=GO_REF:0000037, GO:0043687=Reactome:REACT_22161} P51690 Arylsulfatase E protein 20130301 {GO:0006665=TAS, GO:0001501=TAS, GO:0006687=TAS, GO:0005795=IEA, GO:0005788=TAS, GO:0004065=TAS, GO:0044281=TAS, GO:0008484=IEA, GO:0044267=TAS, GO:0046872=IEA, GO:0043687=TAS} cellular protein metabolic process, glycosphingolipid metabolic process, post-translational protein modification, skeletal system development, small molecule metabolic process, sphingolipid metabolic process Golgi stack, endoplasmic reticulum lumen arylsulfatase activity, metal ion binding, sulfuric ester hydrolase activity Human ARSF Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0006687=Reactome:REACT_116105, GO:0005788=Reactome:REACT_121125, GO:0004065=PMID:9192838, GO:0005576=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0044267=Reactome:REACT_17015, GO:0046872=GO_REF:0000037, GO:0043687=Reactome:REACT_22161} P54793 Arylsulfatase F protein 20130301 {GO:0006665=TAS, GO:0006687=TAS, GO:0005788=TAS, GO:0004065=TAS, GO:0005576=IEA, GO:0044281=TAS, GO:0044267=TAS, GO:0046872=IEA, GO:0043687=TAS} cellular protein metabolic process, glycosphingolipid metabolic process, post-translational protein modification, small molecule metabolic process, sphingolipid metabolic process endoplasmic reticulum lumen, extracellular region arylsulfatase activity, metal ion binding Human ART1 Reactome UniProtKB {GO:0006471=GO_REF:0000002, GO:0005886=Reactome:REACT_115620, GO:0009986=GO_REF:0000019, GO:0005887=PMID:7947688, GO:0045087=Reactome:REACT_6802, GO:0003956=GO_REF:0000003, GO:0033017=GO_REF:0000039, GO:0031225=GO_REF:0000037, GO:0003950=GO_REF:0000019} P52961 GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 protein 20130301 {GO:0006471=IEA, GO:0005886=TAS, GO:0009986=IEA, GO:0005887=TAS, GO:0045087=TAS, GO:0003956=IEA, GO:0033017=IEA, GO:0031225=IEA, GO:0003950=IEA} innate immune response, protein ADP-ribosylation anchored to membrane, cell surface, integral to plasma membrane, plasma membrane, sarcoplasmic reticulum membrane NAD(P)+-protein-arginine ADP-ribosyltransferase activity, NAD+ ADP-ribosyltransferase activity Human ART3 InterPro UniProtKB {GO:0006471=GO_REF:0000002, GO:0005887=PMID:9119374, GO:0003956=GO_REF:0000002, GO:0031225=GO_REF:0000037, GO:0003950=PMID:9119374} Q5J1K9 Mono-ADP-ribosyltransferase 3 variant Ia protein 20130413 {GO:0006471=IEA, GO:0005887=TAS, GO:0003956=IEA, GO:0031225=IEA, GO:0003950=TAS} protein ADP-ribosylation anchored to membrane, integral to plasma membrane NAD(P)+-protein-arginine ADP-ribosyltransferase activity, NAD+ ADP-ribosyltransferase activity Human InterPro:IPR000768 ART4 UniProtKB UniProtKB {GO:0006471=PMID:9119374, GO:0016020=PMID:9119374, GO:0005886=GO_REF:0000039, GO:0003956=PMID:9119374, GO:0006525=PMID:11001920, GO:0031225=GO_REF:0000037} Q93070 Ecto-ADP-ribosyltransferase 4 protein 20010921 {GO:0006471=NAS, GO:0016020=NAS, GO:0005886=IEA, GO:0003956=NAS, GO:0006525=NAS, GO:0031225=IEA} arginine metabolic process, protein ADP-ribosylation anchored to membrane, membrane, plasma membrane NAD(P)+-protein-arginine ADP-ribosyltransferase activity Human ARTN Reactome UniProtKB {GO:0050930=GO_REF:0000019, GO:0007165=PMID:9883723, GO:0061146=GO_REF:0000019, GO:0097021=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0007422=GO_REF:0000019, GO:0005102=PMID:9883723, GO:0008083=GO_REF:0000037, GO:0005615=GO_REF:0000019, GO:0007405=PMID:9883723} Q5T4W7 Artemin protein 20130301 {GO:0050930=IEA, GO:0007165=TAS, GO:0061146=IEA, GO:0097021=IEA, GO:0007411=TAS, GO:0007422=IEA, GO:0005102=TAS, GO:0008083=IEA, GO:0005615=IEA, GO:0007405=TAS} Peyer's patch morphogenesis, axon guidance, induction of positive chemotaxis, lymphocyte migration into lymphoid organs, neuroblast proliferation, peripheral nervous system development, signal transduction extracellular space growth factor activity, receptor binding Human ARV1 ENSEMBL UniProtKB {GO:0006665=GO_REF:0000037, GO:0090181=GO_REF:0000019, GO:0008206=GO_REF:0000019, GO:0030301=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q9H2C2 Protein ARV1 protein 20130413 {GO:0006665=IEA, GO:0090181=IEA, GO:0008206=IEA, GO:0030301=IEA, GO:0016021=IEA} bile acid metabolic process, cholesterol transport, regulation of cholesterol metabolic process, sphingolipid metabolic process integral to membrane Human Ensembl:ENSMUSP00000034463 ARVCF PINC UniProtKB {GO:0005622=PMID:9126485, GO:0005515=PMID:19706687, GO:0005737=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0007275=PMID:9126485, GO:0005634=GO_REF:0000019, GO:0007155=GO_REF:0000037} O00192 Armadillo repeat protein deleted in velo-cardio-facial syndrome protein 20030904 {GO:0005622=TAS, GO:0005515=IPI, GO:0005737=IEA, GO:0005886=IEA, GO:0007275=TAS, GO:0005634=IEA, GO:0007155=IEA} cell adhesion, multicellular organismal development cytoplasm, intracellular, nucleus, plasma membrane protein binding Human AS3MT UniProtKB UniProtKB {GO:0030791=GO_REF:0000024, GO:0005739=GO_REF:0000019, GO:0030792=GO_REF:0000024, GO:0009404=GO_REF:0000024, GO:0018872=GO_REF:0000024, GO:0005829=GO_REF:0000024} Q9HBK9 Arsenite methyltransferase protein 20041006 {GO:0030791=ISS, GO:0005739=IEA, GO:0030792=ISS, GO:0009404=ISS, GO:0018872=ISS, GO:0005829=ISS} arsonoacetate metabolic process, toxin metabolic process cytosol, mitochondrion arsenite methyltransferase activity, methylarsonite methyltransferase activity Human UniProtKB:Q8VHT6 ASAH1 Reactome UniProtKB {GO:0006629=GO_REF:0000002, GO:0006665=Reactome:REACT_19323, GO:0008219=GO_REF:0000037, GO:0010033=GO_REF:0000019, GO:0006687=Reactome:REACT_116105, GO:0030324=GO_REF:0000019, GO:0006672=PMID:8955159, GO:0044281=Reactome:REACT_111217, GO:0003824=PMID:8955159, GO:0005764=GO_REF:0000002, GO:0017040=Reactome:REACT_115911, GO:0016787=GO_REF:0000002, GO:0043202=Reactome:REACT_115911} Q13510 Acid ceramidase protein 20110923 {GO:0006629=IEA, GO:0006665=TAS, GO:0008219=IEA, GO:0010033=IEA, GO:0006687=TAS, GO:0030324=IEA, GO:0006672=TAS, GO:0044281=TAS, GO:0003824=TAS, GO:0005764=IEA, GO:0017040=TAS, GO:0016787=IEA, GO:0043202=TAS} cell death, ceramide metabolic process, glycosphingolipid metabolic process, lipid metabolic process, lung development, response to organic substance, small molecule metabolic process, sphingolipid metabolic process lysosomal lumen, lysosome catalytic activity, ceramidase activity, hydrolase activity Human ASAH2 Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0005739=PMID:10781606, GO:0007165=PMID:10781606, GO:0017040=GO_REF:0000003, GO:0006687=Reactome:REACT_116105, GO:0005886=Reactome:REACT_115894, GO:0006672=PMID:10781606, GO:0006915=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037} Q9NR71 Neutral ceramidase protein 20130301 {GO:0006665=TAS, GO:0005739=TAS, GO:0007165=TAS, GO:0017040=IEA, GO:0006687=TAS, GO:0005886=TAS, GO:0006672=TAS, GO:0006915=IEA, GO:0044281=TAS, GO:0016021=IEA} apoptotic process, ceramide metabolic process, glycosphingolipid metabolic process, signal transduction, small molecule metabolic process, sphingolipid metabolic process integral to membrane, mitochondrion, plasma membrane ceramidase activity Human ASAH2B null null {} null null null null {} null null null ASAP1 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0008060=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0032312=GO_REF:0000002, GO:0060271=PMID:20393563, GO:0008270=GO_REF:0000002} Q9ULH1 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 protein 20130415 {GO:0005515=IPI, GO:0008060=IEA, GO:0005737=IEA, GO:0005543=IEA, GO:0016020=IEA, GO:0032312=IEA, GO:0060271=IMP, GO:0008270=IEA} cilium morphogenesis, regulation of ARF GTPase activity cytoplasm, membrane ARF GTPase activator activity, phospholipid binding, protein binding, zinc ion binding Human UniProtKB:P62993 ASAP2 GOC UniProtKB {GO:0005515=PMID:21706016, GO:0008060=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0032312=GO_REF:0000002, GO:0032580=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0043085=PMID:9819391, GO:0008047=PMID:9819391} O43150 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 protein 20130413 {GO:0005515=IPI, GO:0008060=IEA, GO:0005543=IEA, GO:0005886=IEA, GO:0032312=IEA, GO:0032580=IEA, GO:0008270=IEA, GO:0043085=TAS, GO:0008047=TAS} positive regulation of catalytic activity, regulation of ARF GTPase activity Golgi cisterna membrane, plasma membrane ARF GTPase activator activity, enzyme activator activity, phospholipid binding, protein binding, zinc ion binding Human ASAP3 UniProtKB UniProtKB {GO:0008060=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0032312=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q8TDY4 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 protein 20130413 {GO:0008060=IEA, GO:0005737=IEA, GO:0005543=IEA, GO:0032312=IEA, GO:0008270=IEA} regulation of ARF GTPase activity cytoplasm ARF GTPase activator activity, phospholipid binding, zinc ion binding Human UniProtKB-SubCell:SL-0086 ASB1 UniProtKB UniProtKB {GO:0005622=PMID:11111040, GO:0042036=PMID:11111040, GO:0035556=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0030539=GO_REF:0000019, GO:0016567=GO_REF:0000041} Q9Y576 Ankyrin repeat and SOCS box protein 1 protein 20040225 {GO:0005622=IC, GO:0042036=NAS, GO:0035556=IEA, GO:0003674=ND, GO:0030539=IEA, GO:0016567=IEA} intracellular signal transduction, male genitalia development, negative regulation of cytokine biosynthetic process, protein ubiquitination intracellular molecular_function Human GO:0042036 ASB10 UniPathway UniProtKB {GO:0035556=GO_REF:0000002, GO:0016567=GO_REF:0000041} Q8WXI3 Ankyrin repeat and SOCS box protein 10 protein 20130413 {GO:0035556=IEA, GO:0016567=IEA} intracellular signal transduction, protein ubiquitination Human UniPathway:UPA00143 ASB12 UniPathway UniProtKB {GO:0035556=GO_REF:0000002, GO:0016567=GO_REF:0000041} Q8WXK4 Ankyrin repeat and SOCS box protein 12 protein 20130413 {GO:0035556=IEA, GO:0016567=IEA} intracellular signal transduction, protein ubiquitination Human UniPathway:UPA00143 ASB13 IntAct UniProtKB {GO:0005515=PMID:16169070, GO:0035556=GO_REF:0000002, GO:0016567=GO_REF:0000041} Q8WXK3 Ankyrin repeat and SOCS box protein 13 protein 20130415 {GO:0005515=IPI, GO:0035556=IEA, GO:0016567=IEA} intracellular signal transduction, protein ubiquitination protein binding Human UniProtKB:P27448 ASB16 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0035556=GO_REF:0000002, GO:0016567=GO_REF:0000041} Q96NS5 Ankyrin repeat and SOCS box protein 16 protein 20130415 {GO:0005515=IPI, GO:0035556=IEA, GO:0016567=IEA} intracellular signal transduction, protein ubiquitination protein binding Human UniProtKB:P16333 ASB17 UniPathway UniProtKB {GO:0035556=GO_REF:0000002, GO:0016567=GO_REF:0000041} Q8WXJ9 Ankyrin repeat and SOCS box protein 17 protein 20130413 {GO:0035556=IEA, GO:0016567=IEA} intracellular signal transduction, protein ubiquitination Human UniPathway:UPA00143 ASB2 PINC UniProtKB {GO:0035556=GO_REF:0000002, GO:0007165=PMID:9419338, GO:0016567=GO_REF:0000041} Q96Q27 Ankyrin repeat and SOCS box protein 2 protein 20050308 {GO:0035556=IEA, GO:0007165=TAS, GO:0016567=IEA} intracellular signal transduction, protein ubiquitination, signal transduction Human ASB3 UniPathway UniProtKB {GO:0035556=GO_REF:0000002, GO:0016567=GO_REF:0000041} Q9Y575 Ankyrin repeat and SOCS box protein 3 protein 20130413 {GO:0035556=IEA, GO:0016567=IEA} intracellular signal transduction, protein ubiquitination Human UniPathway:UPA00143 ASB4 UniProtKB UniProtKB {GO:0035556=GO_REF:0000002, GO:0004842=GO_REF:0000019, GO:2001214=GO_REF:0000024, GO:0031462=PMID:17636018, GO:0031466=PMID:17636018, GO:0031625=GO_REF:0000019, GO:0051865=GO_REF:0000019} Q9Y574 Ankyrin repeat and SOCS box protein 4 protein 20120313 {GO:0035556=IEA, GO:0004842=IEA, GO:2001214=ISS, GO:0031462=IDA, GO:0031466=IDA, GO:0031625=IEA, GO:0051865=IEA} intracellular signal transduction, positive regulation of vasculogenesis, protein autoubiquitination Cul2-RING ubiquitin ligase complex, Cul5-RING ubiquitin ligase complex ubiquitin protein ligase binding, ubiquitin-protein ligase activity Human UniProtKB:Q9WV71 ASB6 UniPathway UniProtKB {GO:0035556=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0016567=GO_REF:0000041} Q9NWX5 Ankyrin repeat and SOCS box protein 6 protein 20130413 {GO:0035556=IEA, GO:0005737=IEA, GO:0016567=IEA} intracellular signal transduction, protein ubiquitination cytoplasm Human UniPathway:UPA00143 ASB7 UniPathway UniProtKB {GO:0035556=GO_REF:0000002, GO:0016567=GO_REF:0000041} Q9H672 Ankyrin repeat and SOCS box protein 7 protein 20130413 {GO:0035556=IEA, GO:0016567=IEA} intracellular signal transduction, protein ubiquitination Human UniPathway:UPA00143 ASB8 HPA UniProtKB {GO:0035556=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0016567=GO_REF:0000041, GO:0005634=GO_REF:0000052} Q9H765 Ankyrin repeat and SOCS box protein 8 protein 20080205 {GO:0035556=IEA, GO:0005737=IDA, GO:0016567=IEA, GO:0005634=IDA} intracellular signal transduction, protein ubiquitination cytoplasm, nucleus Human ASB9 HPA UniProtKB {GO:0005515=PMID:19060904, GO:0005739=GO_REF:0000039, GO:0035556=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0045732=PMID:17148442, GO:0016567=PMID:17148442, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q96DX5 Ankyrin repeat and SOCS box protein 9 protein 20101115 {GO:0005515=IPI, GO:0005739=IEA, GO:0035556=IEA, GO:0005737=IDA, GO:0045732=IDA, GO:0016567=IDA, GO:0005730=IDA, GO:0005634=IDA} intracellular signal transduction, positive regulation of protein catabolic process, protein ubiquitination cytoplasm, mitochondrion, nucleolus, nucleus protein binding Human ASCC1 MGI UniProtKB {GO:0005667=PMID:12077347, GO:0006355=PMID:12077347, GO:0005737=GO_REF:0000039, GO:0016070=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0003824=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q8N9N2 Activating signal cointegrator 1 complex subunit 1 protein 20091020 {GO:0005667=IDA, GO:0006355=IDA, GO:0005737=IEA, GO:0016070=IEA, GO:0003723=IEA, GO:0003824=IEA, GO:0006351=IEA} RNA metabolic process, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, transcription factor complex RNA binding, catalytic activity Human ASCC2 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9H1I8 Activating signal cointegrator 1 complex subunit 2 protein 20130413 {GO:0006355=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent Human UniProtKB-KW:KW-0805 ASCC3 LIFEdb UniProtKB {GO:0005515=PMID:22055184, GO:0006355=GO_REF:0000037, GO:0043140=PMID:22055184, GO:0005794=GO_REF:0000052, GO:0008283=PMID:22055184, GO:0005634=PMID:22055184, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0005622=GO_REF:0000054, GO:0005737=GO_REF:0000039, GO:0006307=PMID:22055184, GO:0032508=PMID:22055184} Q8N3C0 Activating signal cointegrator 1 complex subunit 3 protein 20100607 {GO:0005515=IPI, GO:0006355=IEA, GO:0043140=IDA, GO:0005794=IDA, GO:0008283=IMP, GO:0005634=TAS, GO:0003676=IEA, GO:0005524=IEA, GO:0006351=IEA, GO:0005622=IDA, GO:0005737=IEA, GO:0006307=IDA, GO:0032508=IDA} DNA dealkylation involved in DNA repair, DNA duplex unwinding, cell proliferation, regulation of transcription, DNA-dependent, transcription, DNA-dependent Golgi apparatus, cytoplasm, intracellular, nucleus ATP binding, ATP-dependent 3'-5' DNA helicase activity, nucleic acid binding, protein binding Human ASCL1 IntAct UniProtKB {GO:0005515=PMID:10903890, GO:0007389=GO_REF:0000019, GO:0003700=PMID:10903890, GO:0061104=GO_REF:0000019, GO:0061103=GO_REF:0000019, GO:0061102=GO_REF:0000019, GO:0061100=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0000989=GO_REF:0000024, GO:0007405=GO_REF:0000019, GO:0071259=GO_REF:0000019, GO:0003690=GO_REF:0000019, GO:0043525=GO_REF:0000019, GO:0007219=PMID:16160079, GO:0043025=GO_REF:0000019, GO:0021892=PMID:12050665, GO:0045747=GO_REF:0000019, GO:2000179=GO_REF:0000019, GO:0021879=GO_REF:0000019, GO:0070888=PMID:11736660, GO:0045787=GO_REF:0000019, GO:0048485=PMID:10903890, GO:0070849=GO_REF:0000019, GO:0051593=GO_REF:0000019, GO:0060487=PMID:12858003, GO:0003359=PMID:14532329, GO:0021987=GO_REF:0000019, GO:0021530=GO_REF:0000019, GO:0005634=PMID:18311112, GO:0050769=GO_REF:0000019, GO:0045944=PMID:10903890, GO:0060166=GO_REF:0000019, GO:0060165=GO_REF:0000019, GO:0032526=PMID:12000752, GO:0060163=GO_REF:0000019, GO:0022008=PMID:19008346, GO:0043066=PMID:17507989, GO:0021954=GO_REF:0000019, GO:0048665=GO_REF:0000019, GO:0043425=PMID:10903890, GO:0003677=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0021527=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0010226=GO_REF:0000019, GO:0007400=GO_REF:0000019, GO:0045665=PMID:12000752, GO:0045666=GO_REF:0000024, GO:0014003=GO_REF:0000019, GO:0021750=GO_REF:0000019, GO:0001764=GO_REF:0000019} P50553 Achaete-scute homolog 1 protein 20130415 {GO:0005515=IPI, GO:0007389=IEA, GO:0003700=IDA, GO:0061104=IEA, GO:0061103=IEA, GO:0061102=IEA, GO:0061100=IEA, GO:0042803=IEA, GO:0000989=ISS, GO:0007405=IEA, GO:0071259=IEA, GO:0003690=IEA, GO:0043525=IEA, GO:0007219=IDA, GO:0043025=IEA, GO:0021892=IEP, GO:0045747=IEA, GO:2000179=IEA, GO:0021879=IEA, GO:0070888=IDA, GO:0045787=IEA, GO:0048485=NAS, GO:0070849=IEA, GO:0051593=IEA, GO:0060487=NAS, GO:0003359=IMP, GO:0021987=IEA, GO:0021530=IEA, GO:0005634=IDA, GO:0050769=IEA, GO:0045944=IDA, GO:0060166=IEA, GO:0060165=IEA, GO:0032526=IEP, GO:0060163=IEA, GO:0022008=IDA, GO:0043066=IMP, GO:0021954=IEA, GO:0048665=IEA, GO:0043425=IPI, GO:0003677=ISS, GO:0006351=IEA, GO:0021527=IEA, GO:0043565=IEA, GO:0010226=IEA, GO:0007400=IEA, GO:0045665=IDA, GO:0045666=ISS, GO:0014003=IEA, GO:0021750=IEA, GO:0001764=IEA} Notch signaling pathway, adrenal chromaffin cell differentiation, carotid body glomus cell differentiation, cellular response to magnetism, central nervous system neuron development, cerebral cortex GABAergic interneuron differentiation, cerebral cortex development, forebrain neuron differentiation, lung epithelial cell differentiation, lung neuroendocrine cell differentiation, negative regulation of apoptotic process, negative regulation of neuron differentiation, neuroblast fate determination, neuroblast proliferation, neurogenesis, neuron fate specification, neuron migration, noradrenergic neuron fate commitment, olfactory pit development, oligodendrocyte development, pattern specification process, positive regulation of Notch signaling pathway, positive regulation of cell cycle, positive regulation of neural precursor cell proliferation, positive regulation of neurogenesis, positive regulation of neuron apoptotic process, positive regulation of neuron differentiation, positive regulation of transcription from RNA polymerase II promoter, regulation of timing of subpallium neuron differentiation, response to epidermal growth factor stimulus, response to folic acid, response to lithium ion, response to retinoic acid, spinal cord association neuron differentiation, spinal cord oligodendrocyte cell fate specification, stomach neuroendocrine cell differentiation, subpallium neuron fate commitment, sympathetic nervous system development, transcription, DNA-dependent, vestibular nucleus development neuronal cell body, nucleus DNA binding, E-box binding, bHLH transcription factor binding, double-stranded DNA binding, protein binding, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding transcription factor activity Human UniProtKB:P15923 ASCL2 UniProtKB UniProtKB {GO:0001666=PMID:14561729, GO:0006355=PMID:8751384, GO:0003700=PMID:8751384, GO:0060712=PMID:12917334, GO:0060708=GO_REF:0000019, GO:0070888=PMID:14561729, GO:0005634=PMID:11440538, GO:0000122=PMID:14561729, GO:0001890=PMID:14561729, GO:0007417=GO_REF:0000029, GO:0006351=PMID:14561729, GO:0043565=GO_REF:0000019, GO:0010626=GO_REF:0000019, GO:0007422=GO_REF:0000029, GO:0046983=GO_REF:0000002, GO:0035019=GO_REF:0000019} Q99929 Achaete-scute homolog 2 protein 20011002 {GO:0001666=IEP, GO:0006355=NAS, GO:0003700=NAS, GO:0060712=IEP, GO:0060708=IEA, GO:0070888=IDA, GO:0005634=IDA, GO:0000122=IDA, GO:0001890=NAS, GO:0007417=NAS, GO:0006351=IDA, GO:0043565=IEA, GO:0010626=IEA, GO:0007422=NAS, GO:0046983=IEA, GO:0035019=IEA} central nervous system development, negative regulation of Schwann cell proliferation, negative regulation of transcription from RNA polymerase II promoter, peripheral nervous system development, placenta development, regulation of transcription, DNA-dependent, response to hypoxia, somatic stem cell maintenance, spongiotrophoblast differentiation, spongiotrophoblast layer development, transcription, DNA-dependent nucleus E-box binding, protein dimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human ASCL3 HPA UniProtKB {GO:0005667=GO_REF:0000019, GO:0006357=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000024, GO:0006351=GO_REF:0000024, GO:0043231=GO_REF:0000052} Q9NQ33 Achaete-scute homolog 3 protein 20101115 {GO:0005667=IEA, GO:0006357=ISS, GO:0005730=IDA, GO:0046983=IEA, GO:0005634=IDA, GO:0003677=ISS, GO:0006351=ISS, GO:0043231=IDA} regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent intracellular membrane-bounded organelle, nucleolus, nucleus, transcription factor complex DNA binding, protein dimerization activity Human ASCL4 UniProtKB UniProtKB {GO:0006357=PMID:15475265, GO:0046983=GO_REF:0000002, GO:0043588=PMID:15475265, GO:0005634=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6XD76 Achaete-scute homolog 4 protein 20110107 {GO:0006357=NAS, GO:0046983=IEA, GO:0043588=NAS, GO:0005634=IEA, GO:0005575=ND, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription from RNA polymerase II promoter, skin development, transcription, DNA-dependent cellular_component, nucleus DNA binding, protein dimerization activity Human ASF1A IntAct UniProtKB {GO:0005515=PMID:21217774, GO:0042692=GO_REF:0000019, GO:0042393=PMID:10759893, GO:0006281=PMID:11897662, GO:0003682=PMID:10759893, GO:0006334=PMID:11897662, GO:0005634=GO_REF:0000054, GO:0001649=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0031936=PMID:10759893, GO:0016568=GO_REF:0000037} Q9Y294 Histone chaperone ASF1A protein 20130415 {GO:0005515=IPI, GO:0042692=IEA, GO:0042393=IDA, GO:0006281=IDA, GO:0003682=NAS, GO:0006334=IDA, GO:0005634=IDA, GO:0001649=IEA, GO:0006351=IEA, GO:0031936=NAS, GO:0016568=IEA} DNA repair, chromatin modification, muscle cell differentiation, negative regulation of chromatin silencing, nucleosome assembly, osteoblast differentiation, transcription, DNA-dependent nucleus chromatin binding, histone binding, protein binding Human UniProtKB:P03372 ASF1B UniProtKB UniProtKB {GO:0005515=PMID:22407294, GO:0042393=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0006334=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0007283=GO_REF:0000037, GO:0000785=GO_REF:0000019, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037, GO:0006333=GO_REF:0000002} Q9NVP2 Histone chaperone ASF1B protein 20121123 {GO:0005515=IPI, GO:0042393=IEA, GO:0006355=IEA, GO:0006334=IEA, GO:0007275=IEA, GO:0005634=IEA, GO:0007283=IEA, GO:0000785=IEA, GO:0030154=IEA, GO:0006351=IEA, GO:0016568=IEA, GO:0006333=IEA} cell differentiation, chromatin assembly or disassembly, chromatin modification, multicellular organismal development, nucleosome assembly, regulation of transcription, DNA-dependent, spermatogenesis, transcription, DNA-dependent chromatin, nucleus histone binding, protein binding Human UniProtKB:Q8IWY9 ASGR1 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0005887=PMID:10734069, GO:0031668=GO_REF:0000019, GO:0004873=GO_REF:0000019, GO:0030246=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0006898=PMID:8439566, GO:0046872=GO_REF:0000037, GO:0042803=GO_REF:0000019} P07306 Asialoglycoprotein receptor 1 protein 20130415 {GO:0005515=IPI, GO:0005887=TAS, GO:0031668=IEA, GO:0004873=IEA, GO:0030246=IEA, GO:0005576=IEA, GO:0006898=TAS, GO:0046872=IEA, GO:0042803=IEA} cellular response to extracellular stimulus, receptor-mediated endocytosis extracellular region, integral to plasma membrane asialoglycoprotein receptor activity, carbohydrate binding, metal ion binding, protein binding, protein homodimerization activity Human UniProtKB:Q96G23 ASGR2 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0009100=GO_REF:0000019, GO:0031647=GO_REF:0000019, GO:0055088=GO_REF:0000019, GO:0004873=PMID:3863106, GO:0030246=GO_REF:0000002, GO:0030282=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007166=PMID:3863106} P07307 Asialoglycoprotein receptor 2 protein 20130415 {GO:0005515=IPI, GO:0009100=IEA, GO:0031647=IEA, GO:0055088=IEA, GO:0004873=TAS, GO:0030246=IEA, GO:0030282=IEA, GO:0016021=IEA, GO:0007166=TAS} bone mineralization, cell surface receptor signaling pathway, glycoprotein metabolic process, lipid homeostasis, regulation of protein stability integral to membrane asialoglycoprotein receptor activity, carbohydrate binding, protein binding Human UniProtKB:Q96G23 ASH1L HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0005794=GO_REF:0000052, GO:0006366=PMID:10860993, GO:0005694=GO_REF:0000039, GO:0007267=PMID:10860993, GO:0005730=GO_REF:0000052, GO:0006323=PMID:10860993, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000002, GO:0018024=GO_REF:0000003, GO:0005737=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0005923=GO_REF:0000039} Q9NR48 Histone-lysine N-methyltransferase ASH1L protein 20101115 {GO:0006355=IEA, GO:0005794=IDA, GO:0006366=TAS, GO:0005694=IEA, GO:0007267=TAS, GO:0005730=IDA, GO:0006323=TAS, GO:0005634=IDA, GO:0003677=IEA, GO:0018024=IEA, GO:0005737=IDA, GO:0008270=IEA, GO:0005923=IEA} DNA packaging, cell-cell signaling, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter Golgi apparatus, chromosome, cytoplasm, nucleolus, nucleus, tight junction DNA binding, histone-lysine N-methyltransferase activity, zinc ion binding Human ASH2L IntAct UniProtKB {GO:0005515=PMID:19556245, GO:0030097=PMID:11466562, GO:0008284=PMID:18245475, GO:0006355=PMID:10393421, GO:0043627=PMID:16603732, GO:0006366=PMID:10393421, GO:0044212=PMID:16603732, GO:0005634=PMID:17500065, GO:0042800=PMID:17355966, GO:0003677=PMID:10393421, GO:0006974=PMID:17500065, GO:0046872=GO_REF:0000037, GO:0006351=PMID:10393421, GO:0035097=PMID:14992727, GO:0045944=GO_REF:0000019, GO:0048188=PMID:18838538, GO:0051568=PMID:17355966} Q9UBL3 Set1/Ash2 histone methyltransferase complex subunit ASH2 protein 20130415 {GO:0005515=IPI, GO:0030097=NAS, GO:0008284=IMP, GO:0006355=NAS, GO:0043627=IDA, GO:0006366=TAS, GO:0044212=IDA, GO:0005634=IDA, GO:0042800=IDA, GO:0003677=IC, GO:0006974=IDA, GO:0046872=IEA, GO:0006351=NAS, GO:0035097=IPI, GO:0045944=IEA, GO:0048188=IDA, GO:0051568=IDA} hemopoiesis, histone H3-K4 methylation, positive regulation of cell proliferation, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, response to DNA damage stimulus, response to estrogen stimulus, transcription from RNA polymerase II promoter, transcription, DNA-dependent Set1C/COMPASS complex, histone methyltransferase complex, nucleus DNA binding, histone methyltransferase activity (H3-K4 specific), metal ion binding, protein binding, transcription regulatory region DNA binding Human UniProtKB:Q9C005 ASIP PINC UniProtKB {GO:0008343=GO_REF:0000019, GO:0032438=GO_REF:0000019, GO:0007267=PMID:7757071, GO:0005102=PMID:7757071, GO:0006091=GO_REF:0000019, GO:0005615=PMID:7937887, GO:0032402=GO_REF:0000019, GO:0040030=GO_REF:0000019, GO:0007165=PMID:7757071, GO:0009755=GO_REF:0000002, GO:0042438=GO_REF:0000019, GO:0031781=GO_REF:0000019, GO:0071514=GO_REF:0000019, GO:0031782=GO_REF:0000019} P42127 Agouti-signaling protein protein 20030904 {GO:0008343=IEA, GO:0032438=IEA, GO:0007267=TAS, GO:0005102=TAS, GO:0006091=IEA, GO:0005615=TAS, GO:0032402=IEA, GO:0040030=IEA, GO:0007165=TAS, GO:0009755=IEA, GO:0042438=IEA, GO:0031781=IEA, GO:0071514=IEA, GO:0031782=IEA} adult feeding behavior, cell-cell signaling, generation of precursor metabolites and energy, genetic imprinting, hormone-mediated signaling pathway, melanin biosynthetic process, melanosome organization, melanosome transport, regulation of molecular function, epigenetic, signal transduction extracellular space receptor binding, type 3 melanocortin receptor binding, type 4 melanocortin receptor binding Human ASL Reactome UniProtKB {GO:0034641=Reactome:REACT_13, GO:0042450=GO_REF:0000002, GO:0005737=PMID:282632, GO:0000050=Reactome:REACT_847, GO:0044281=Reactome:REACT_111217, GO:0006527=PMID:282632, GO:0006475=PMID:20167786, GO:0004056=Reactome:REACT_1378, GO:0005829=Reactome:REACT_1378} P04424 Argininosuccinate lyase protein 20130213 {GO:0034641=TAS, GO:0042450=IEA, GO:0005737=TAS, GO:0000050=TAS, GO:0044281=TAS, GO:0006527=TAS, GO:0006475=IDA, GO:0004056=EXP, GO:0005829=TAS} arginine biosynthetic process via ornithine, arginine catabolic process, cellular nitrogen compound metabolic process, internal protein amino acid acetylation, small molecule metabolic process, urea cycle cytoplasm, cytosol argininosuccinate lyase activity Human ASMTL HPA UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0008171=GO_REF:0000002} O95671 N-acetylserotonin O-methyltransferase-like protein protein 20080205 {GO:0003674=ND, GO:0008150=ND, GO:0005737=IDA, GO:0008171=IEA} biological_process cytoplasm O-methyltransferase activity, molecular_function Human ASNA1 PINC UniProtKB {GO:0005215=PMID:9736449, GO:0005737=PMID:9736449, GO:0005783=GO_REF:0000039, GO:0015105=PMID:8884272, GO:0006810=PMID:9736449, GO:0005730=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002, GO:0046872=GO_REF:0000037} O43681 ATPase ASNA1 protein 20030904 {GO:0005215=TAS, GO:0005737=TAS, GO:0005783=IEA, GO:0015105=TAS, GO:0006810=TAS, GO:0005730=IEA, GO:0005524=IEA, GO:0016887=IEA, GO:0046872=IEA} transport cytoplasm, endoplasmic reticulum, nucleolus ATP binding, ATPase activity, arsenite transmembrane transporter activity, metal ion binding, transporter activity Human ASNS Reactome UniProtKB {GO:0070981=GO_REF:0000041, GO:0031427=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0042803=GO_REF:0000019, GO:0032870=GO_REF:0000019, GO:0005829=Reactome:REACT_115759, GO:0030968=Reactome:REACT_18356, GO:0034641=Reactome:REACT_13, GO:0004066=Reactome:REACT_277, GO:0009416=GO_REF:0000019, GO:0042149=PMID:10085239, GO:0043200=GO_REF:0000019, GO:0006529=PMID:2573597, GO:0032354=GO_REF:0000019, GO:0048037=GO_REF:0000019, GO:0043066=PMID:17409444, GO:0009636=GO_REF:0000019, GO:0008652=Reactome:REACT_238, GO:0005524=GO_REF:0000037, GO:0009612=GO_REF:0000019, GO:0001889=GO_REF:0000019, GO:0045931=PMID:2569668, GO:0006987=Reactome:REACT_18277, GO:0044267=Reactome:REACT_17015, GO:0006541=GO_REF:0000037} P08243 "Asparagine synthetase ""glutamine-hydrolyzing""" protein 20130213 {GO:0070981=IEA, GO:0031427=IEA, GO:0044281=TAS, GO:0042803=IEA, GO:0032870=IEA, GO:0005829=TAS, GO:0030968=TAS, GO:0034641=TAS, GO:0004066=EXP, GO:0009416=IEA, GO:0042149=IDA, GO:0043200=IEA, GO:0006529=IDA, GO:0032354=IEA, GO:0048037=IEA, GO:0043066=IMP, GO:0009636=IEA, GO:0008652=TAS, GO:0005524=IEA, GO:0009612=IEA, GO:0001889=IEA, GO:0045931=IDA, GO:0006987=TAS, GO:0044267=TAS, GO:0006541=IEA} L-asparagine biosynthetic process, activation of signaling protein activity involved in unfolded protein response, asparagine biosynthetic process, cellular amino acid biosynthetic process, cellular nitrogen compound metabolic process, cellular protein metabolic process, cellular response to glucose starvation, cellular response to hormone stimulus, endoplasmic reticulum unfolded protein response, glutamine metabolic process, liver development, negative regulation of apoptotic process, positive regulation of mitotic cell cycle, response to amino acid stimulus, response to follicle-stimulating hormone stimulus, response to light stimulus, response to mechanical stimulus, response to methotrexate, response to toxic substance, small molecule metabolic process cytosol ATP binding, asparagine synthase (glutamine-hydrolyzing) activity, cofactor binding, protein homodimerization activity Human ASNSD1 BHF-UCL UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0004066=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0006529=GO_REF:0000037, GO:0006541=GO_REF:0000037} Q9NWL6 Asparagine synthetase domain-containing protein 1 protein 20120601 {GO:0008150=ND, GO:0003674=ND, GO:0004066=IEA, GO:0005575=ND, GO:0006529=IEA, GO:0006541=IEA} asparagine biosynthetic process, biological_process, glutamine metabolic process cellular_component asparagine synthase (glutamine-hydrolyzing) activity, molecular_function Human ASPA HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0019807=GO_REF:0000003, GO:0006533=PMID:8252036, GO:0022010=GO_REF:0000019, GO:0048714=GO_REF:0000019, GO:0016788=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0004046=PMID:8252036, GO:0046872=GO_REF:0000037} P45381 Aspartoacylase protein 20100326 {GO:0005737=IDA, GO:0019807=IEA, GO:0006533=TAS, GO:0022010=IEA, GO:0048714=IEA, GO:0016788=IEA, GO:0005634=IEA, GO:0004046=TAS, GO:0046872=IEA} aspartate catabolic process, central nervous system myelination, positive regulation of oligodendrocyte differentiation cytoplasm, nucleus aminoacylase activity, aspartoacylase activity, hydrolase activity, acting on ester bonds, metal ion binding Human ASPH BHF-UCL UniProtKB {GO:0005515=PMID:22586105, GO:0032541=PMID:21062895, GO:0007389=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0005886=PMID:21062895, GO:0005783=PMID:11007777, GO:0042264=GO_REF:0000019, GO:0005509=PMID:11007777, GO:0004597=GO_REF:0000003, GO:0009055=PMID:7821814, GO:0097202=PMID:18387192, GO:0045862=PMID:18387192, GO:0008150=GO_REF:0000015, GO:0006936=PMID:10974562, GO:0016020=GO_REF:0000002, GO:0060325=GO_REF:0000019, GO:0005198=PMID:11007777, GO:0018193=GO_REF:0000002, GO:0005789=PMID:11007777, GO:0060021=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0008307=PMID:11007777, GO:0016702=GO_REF:0000037, GO:0035108=GO_REF:0000019} Q12797 Aspartyl/asparaginyl beta-hydroxylase protein 20130219 {GO:0005515=IPI, GO:0032541=IDA, GO:0007389=IEA, GO:0008285=IEA, GO:0005886=IDA, GO:0005783=TAS, GO:0042264=IEA, GO:0005509=NAS, GO:0004597=IEA, GO:0009055=TAS, GO:0097202=IDA, GO:0045862=IDA, GO:0008150=ND, GO:0006936=TAS, GO:0016020=IEA, GO:0060325=IEA, GO:0005198=TAS, GO:0018193=IEA, GO:0005789=NAS, GO:0060021=IEA, GO:0016021=IEA, GO:0008307=TAS, GO:0016702=IEA, GO:0035108=IEA} activation of cysteine-type endopeptidase activity, biological_process, face morphogenesis, limb morphogenesis, muscle contraction, negative regulation of cell proliferation, palate development, pattern specification process, peptidyl-amino acid modification, peptidyl-aspartic acid hydroxylation, positive regulation of proteolysis cortical endoplasmic reticulum, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, membrane, plasma membrane calcium ion binding, electron carrier activity, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, peptide-aspartate beta-dioxygenase activity, protein binding, structural constituent of muscle, structural molecule activity Human ASPM UniProtKB UniProtKB {GO:0005516=GO_REF:0000037, GO:0048477=GO_REF:0000019, GO:0090263=GO_REF:0000019, GO:0002052=GO_REF:0000019, GO:0030496=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0007283=GO_REF:0000019, GO:0021873=GO_REF:0000019, GO:0045769=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0007067=GO_REF:0000037, GO:0000922=GO_REF:0000019, GO:0048589=GO_REF:0000019, GO:0051661=GO_REF:0000019, GO:0045665=GO_REF:0000019, GO:0001764=GO_REF:0000019} Q8IZT6 Abnormal spindle-like microcephaly-associated protein protein 20130413 {GO:0005516=IEA, GO:0048477=IEA, GO:0090263=IEA, GO:0002052=IEA, GO:0030496=IEA, GO:0005634=IEA, GO:0007283=IEA, GO:0021873=IEA, GO:0045769=IEA, GO:0005737=IEA, GO:0007067=IEA, GO:0000922=IEA, GO:0048589=IEA, GO:0051661=IEA, GO:0045665=IEA, GO:0001764=IEA} developmental growth, forebrain neuroblast division, maintenance of centrosome location, mitosis, negative regulation of asymmetric cell division, negative regulation of neuron differentiation, neuron migration, oogenesis, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of neuroblast proliferation, spermatogenesis cytoplasm, midbody, nucleus, spindle pole calmodulin binding Human UniProtKB-SubCell:SL-0086 ASPRV1 UniProtKB UniProtKB {GO:0016485=PMID:16098038, GO:0006508=GO_REF:0000037, GO:0043588=GO_REF:0000024, GO:0016021=PMID:16098038, GO:0004190=PMID:16098038} Q53RT3 Retroviral-like aspartic protease 1 protein 20061121 {GO:0016485=IDA, GO:0006508=IEA, GO:0043588=ISS, GO:0016021=RCA, GO:0004190=IDA} protein processing, proteolysis, skin development integral to membrane aspartic-type endopeptidase activity Human UniProtKB:Q09PK2 ASPSCR1 IntAct UniProtKB {GO:0012506=GO_REF:0000019, GO:0005515=PMID:18775313, GO:0048471=GO_REF:0000019, GO:0042593=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0006886=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0046324=GO_REF:0000019, GO:0009898=GO_REF:0000019, GO:0016044=Reactome:REACT_11123, GO:0019898=GO_REF:0000019} Q9BZE9 Tether containing UBX domain for GLUT4 protein 20130415 {GO:0012506=IEA, GO:0005515=IPI, GO:0048471=IEA, GO:0042593=IEA, GO:0005575=ND, GO:0006886=IEA, GO:0005829=IEA, GO:0008150=ND, GO:0003674=ND, GO:0046324=IEA, GO:0009898=IEA, GO:0016044=TAS, GO:0019898=IEA} biological_process, cellular membrane organization, glucose homeostasis, intracellular protein transport, regulation of glucose import cellular_component, cytosol, extrinsic to membrane, internal side of plasma membrane, perinuclear region of cytoplasm, vesicle membrane molecular_function, protein binding Human UniProtKB:P55072 ASRGL1 HPA UniProtKB {GO:0008798=PMID:19839645, GO:0005737=GO_REF:0000024, GO:0033345=PMID:19839645, GO:0016787=GO_REF:0000002, GO:0015630=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0004067=PMID:19839645, GO:0006508=GO_REF:0000037, GO:0003948=PMID:19839645, GO:0005634=GO_REF:0000052} Q7L266 Isoaspartyl peptidase/L-asparaginase protein 20101115 {GO:0008798=IDA, GO:0005737=ISS, GO:0033345=IDA, GO:0016787=IEA, GO:0015630=IDA, GO:0005730=IDA, GO:0004067=IDA, GO:0006508=IEA, GO:0003948=IDA, GO:0005634=IDA} asparagine catabolic process via L-aspartate, proteolysis cytoplasm, microtubule cytoskeleton, nucleolus, nucleus N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity, asparaginase activity, beta-aspartyl-peptidase activity, hydrolase activity Human ASS1 InterPro UniProtKB {GO:0005515=PMID:12620389, GO:0034641=Reactome:REACT_13, GO:0005737=PMID:6194510, GO:0006526=GO_REF:0000002, GO:0000050=Reactome:REACT_847, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000002, GO:0005829=Reactome:REACT_482, GO:0004055=GO_REF:0000002} Q5T6L7 Argininosuccinate synthase protein 20130413 {GO:0005515=IPI, GO:0034641=TAS, GO:0005737=TAS, GO:0006526=IEA, GO:0000050=TAS, GO:0044281=TAS, GO:0005524=IEA, GO:0005829=TAS, GO:0004055=IEA} arginine biosynthetic process, cellular nitrogen compound metabolic process, small molecule metabolic process, urea cycle cytoplasm, cytosol ATP binding, argininosuccinate synthase activity, protein binding Human InterPro:IPR001518 ASTL MGI UniProtKB {GO:0030133=GO_REF:0000039, GO:2000360=PMID:22472438, GO:0005886=PMID:22206759, GO:0009566=PMID:22206759, GO:0005737=PMID:22206759, GO:0010954=PMID:22472438, GO:0070002=PMID:22472438, GO:0070001=PMID:22472438, GO:0006508=PMID:15087446, GO:0060468=PMID:22472438, GO:0060473=PMID:22472438, GO:0008233=PMID:15087446, GO:0008270=GO_REF:0000002, GO:0004222=PMID:15087446, GO:0007155=PMID:22206759} Q6HA08 Astacin-like metalloendopeptidase protein 20041210 {GO:0030133=IEA, GO:2000360=ISS, GO:0005886=ISS, GO:0009566=ISS, GO:0005737=ISS, GO:0010954=ISS, GO:0070002=ISS, GO:0070001=ISS, GO:0006508=IDA, GO:0060468=ISS, GO:0060473=ISS, GO:0008233=IDA, GO:0008270=IEA, GO:0004222=IDA, GO:0007155=ISS} cell adhesion, fertilization, negative regulation of binding of sperm to zona pellucida, positive regulation of protein processing, prevention of polyspermy, proteolysis cortical granule, cytoplasm, plasma membrane, transport vesicle aspartic-type peptidase activity, glutamic-type peptidase activity, metalloendopeptidase activity, peptidase activity, zinc ion binding Human ASTN1 UniProtKB UniProtKB {GO:0016477=GO_REF:0000029, GO:0007626=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037, GO:0007158=GO_REF:0000029} O14525 Astrotactin-1 protein 20021104 {GO:0016477=NAS, GO:0007626=IEA, GO:0005575=ND, GO:0016021=IEA, GO:0007158=NAS} cell migration, locomotory behavior, neuron cell-cell adhesion cellular_component, integral to membrane Human ASUN IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0007346=PMID:15737938, GO:0005737=GO_REF:0000024, GO:0007067=GO_REF:0000037, GO:0080154=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0030317=GO_REF:0000024, GO:0051301=GO_REF:0000037} Q9NVM9 Protein asunder homolog protein 20130415 {GO:0005515=IPI, GO:0007346=IMP, GO:0005737=ISS, GO:0007067=IEA, GO:0080154=ISS, GO:0005634=ISS, GO:0030317=ISS, GO:0051301=IEA} cell division, mitosis, regulation of fertilization, regulation of mitotic cell cycle, sperm motility cytoplasm, nucleus protein binding Human UniProtKB:Q13951 ASXL1 IntAct UniProtKB {GO:0005515=PMID:22897849, GO:0000790=GO_REF:0000024, GO:0045599=GO_REF:0000024, GO:0003714=GO_REF:0000024, GO:0003713=GO_REF:0000024, GO:0035359=GO_REF:0000024, GO:0000122=GO_REF:0000024, GO:0042974=GO_REF:0000024, GO:0042975=GO_REF:0000024, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0035517=PMID:20436459, GO:0048386=GO_REF:0000024, GO:0035522=PMID:20436459, GO:0048387=GO_REF:0000024, GO:0045944=GO_REF:0000024, GO:0032526=GO_REF:0000024} Q8IXJ9 Putative Polycomb group protein ASXL1 protein 20130415 {GO:0005515=IPI, GO:0000790=ISS, GO:0045599=ISS, GO:0003714=ISS, GO:0003713=ISS, GO:0035359=ISS, GO:0000122=ISS, GO:0042974=ISS, GO:0042975=ISS, GO:0003677=IEA, GO:0006351=IEA, GO:0046872=IEA, GO:0035517=IDA, GO:0048386=ISS, GO:0035522=IDA, GO:0048387=ISS, GO:0045944=ISS, GO:0032526=ISS} monoubiquitinated histone H2A deubiquitination, negative regulation of fat cell differentiation, negative regulation of peroxisome proliferator activated receptor signaling pathway, negative regulation of retinoic acid receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, positive regulation of retinoic acid receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, response to retinoic acid, transcription, DNA-dependent PR-DUB complex, nuclear chromatin DNA binding, metal ion binding, peroxisome proliferator activated receptor binding, protein binding, retinoic acid receptor binding, transcription coactivator activity, transcription corepressor activity Human UniProtKB:Q92560 ASXL2 UniProtKB UniProtKB {GO:0035360=PMID:21047783, GO:0045944=PMID:21047783, GO:0045600=PMID:21047783, GO:0005634=GO_REF:0000039, GO:0042975=PMID:21047783, GO:0003677=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q76L83 Putative Polycomb group protein ASXL2 protein 20120308 {GO:0035360=IDA, GO:0045944=IDA, GO:0045600=IDA, GO:0005634=IEA, GO:0042975=IDA, GO:0003677=IEA, GO:0046872=IEA, GO:0006351=IEA} positive regulation of fat cell differentiation, positive regulation of peroxisome proliferator activated receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding, metal ion binding, peroxisome proliferator activated receptor binding Human ASZ1 GOC UniProtKB {GO:0007165=PMID:12040005, GO:0005737=GO_REF:0000024, GO:0034587=GO_REF:0000024, GO:0007275=GO_REF:0000037, GO:0071546=GO_REF:0000024, GO:0004871=PMID:12040005, GO:0031047=GO_REF:0000037, GO:0007283=GO_REF:0000024, GO:0030154=GO_REF:0000037, GO:0043046=GO_REF:0000024, GO:0007140=GO_REF:0000024} Q8WWH4 Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 protein 20130413 {GO:0007165=NAS, GO:0005737=ISS, GO:0034587=ISS, GO:0007275=IEA, GO:0071546=ISS, GO:0004871=NAS, GO:0031047=IEA, GO:0007283=ISS, GO:0030154=IEA, GO:0043046=ISS, GO:0007140=ISS} DNA methylation involved in gamete generation, cell differentiation, gene silencing by RNA, male meiosis, multicellular organismal development, piRNA metabolic process, signal transduction, spermatogenesis cytoplasm, pi-body signal transducer activity Human ATAD1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0017111=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000037, GO:0051967=GO_REF:0000024, GO:0045211=GO_REF:0000024, GO:0007613=GO_REF:0000024, GO:0007612=GO_REF:0000024, GO:0016887=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0005778=PMID:21525035, GO:0002092=GO_REF:0000024} Q8NBU5 ATPase family AAA domain-containing protein 1 protein 20120217 {GO:0005739=IEA, GO:0017111=IEA, GO:0030054=IEA, GO:0005886=IEA, GO:0051967=ISS, GO:0045211=ISS, GO:0007613=ISS, GO:0007612=ISS, GO:0016887=ISS, GO:0005524=IEA, GO:0005778=IDA, GO:0002092=ISS} learning, memory, negative regulation of synaptic transmission, glutamatergic, positive regulation of receptor internalization cell junction, mitochondrion, peroxisomal membrane, plasma membrane, postsynaptic membrane ATP binding, ATPase activity, nucleoside-triphosphatase activity Human UniProtKB:Q9D5T0 ATAD2 HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0016887=GO_REF:0000003, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6PL18 ATPase family AAA domain-containing protein 2 protein 20111111 {GO:0006355=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0016887=IEA, GO:0005524=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus, nucleus ATP binding, ATPase activity NOT Human ATAD2B UniProtKB UniProtKB {GO:0017111=GO_REF:0000002, GO:0070577=PMID:22464331, GO:0005524=GO_REF:0000037} Q9ULI0 ATPase family AAA domain-containing protein 2B protein 20120706 {GO:0017111=IEA, GO:0070577=IDA, GO:0005524=IEA} ATP binding, histone acetyl-lysine binding, nucleoside-triphosphatase activity Human ATAD3A UniProtKB UniProtKB {GO:0005739=PMID:20332122, GO:0042645=GO_REF:0000039, GO:0043066=PMID:20332122, GO:0017111=GO_REF:0000002, GO:0005743=GO_REF:0000039, GO:0016049=PMID:20332122, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q9NVI7 ATPase family AAA domain-containing protein 3A protein 20111221 {GO:0005739=IDA, GO:0042645=IEA, GO:0043066=IMP, GO:0017111=IEA, GO:0005743=IEA, GO:0016049=IMP, GO:0016021=IEA, GO:0005524=IEA} cell growth, negative regulation of apoptotic process integral to membrane, mitochondrial inner membrane, mitochondrial nucleoid, mitochondrion ATP binding, nucleoside-triphosphatase activity Human ATAD3B UniProtKB UniProtKB {GO:0017111=GO_REF:0000002, GO:0005743=GO_REF:0000039, GO:0005524=GO_REF:0000037} Q5T9A4 ATPase family AAA domain-containing protein 3B protein 20130413 {GO:0017111=IEA, GO:0005743=IEA, GO:0005524=IEA} mitochondrial inner membrane ATP binding, nucleoside-triphosphatase activity Human UniProtKB-SubCell:SL-0168 ATAD3C UniProtKB UniProtKB {GO:0017111=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q5T2N8 ATPase family AAA domain-containing protein 3C protein 20130413 {GO:0017111=IEA, GO:0005524=IEA} ATP binding, nucleoside-triphosphatase activity Human UniProtKB-KW:KW-0067 ATAD5 UniProtKB UniProtKB {GO:0017111=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0006974=GO_REF:0000037} Q96QE3 ATPase family AAA domain-containing protein 5 protein 20130413 {GO:0017111=IEA, GO:0005634=IEA, GO:0005524=IEA, GO:0006974=IEA} response to DNA damage stimulus nucleus ATP binding, nucleoside-triphosphatase activity Human UniProtKB-SubCell:SL-0191 ATAT1 UniProtKB UniProtKB {GO:0019799=PMID:20829795, GO:0071929=GO_REF:0000002} Q5SQI0 Alpha-tubulin N-acetyltransferase protein 20100915 {GO:0019799=IMP, GO:0071929=IEA} alpha-tubulin acetylation tubulin N-acetyltransferase activity Human ATCAY IntAct UniProtKB {GO:0005515=PMID:16275660, GO:0048311=GO_REF:0000024, GO:0043005=PMID:16899818, GO:0030424=GO_REF:0000024, GO:0031966=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0045202=GO_REF:0000024, GO:0031175=GO_REF:0000024, GO:0030425=GO_REF:0000024, GO:0005739=PMID:16899818, GO:0032880=PMID:16899818, GO:0005737=PMID:16899818, GO:2000212=PMID:16899818, GO:0006810=GO_REF:0000037, GO:0019894=PMID:19861499} Q86WG3 Caytaxin protein 20130415 {GO:0005515=IPI, GO:0048311=ISS, GO:0043005=IDA, GO:0030424=ISS, GO:0031966=ISS, GO:0030054=IEA, GO:0045202=ISS, GO:0031175=ISS, GO:0030425=ISS, GO:0005739=IDA, GO:0032880=IDA, GO:0005737=IDA, GO:2000212=IDA, GO:0006810=IEA, GO:0019894=IPI} mitochondrion distribution, negative regulation of glutamate metabolic process, neuron projection development, regulation of protein localization, transport axon, cell junction, cytoplasm, dendrite, mitochondrial membrane, mitochondrion, neuron projection, synapse kinesin binding, protein binding Human UniProtKB:Q9UNE7 ATE1 InterPro UniProtKB {GO:0005737=PMID:9858543, GO:0004057=GO_REF:0000002, GO:0005634=PMID:9858543, GO:0016598=GO_REF:0000002} Q5SQQ1 Arginyl-tRNA--protein transferase 1 protein 20130413 {GO:0005737=IDA, GO:0004057=IEA, GO:0005634=IDA, GO:0016598=IEA} protein arginylation cytoplasm, nucleus arginyltransferase activity Human InterPro:IPR007471 ATF1 Reactome UniProtKB {GO:0005667=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0038124=Reactome:REACT_8006, GO:0003700=GO_REF:0000002, GO:0034142=Reactome:REACT_6894, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0005634=PMID:8798441, GO:0002224=Reactome:REACT_9020, GO:0051403=Reactome:REACT_21308, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0002756=Reactome:REACT_6809, GO:0045087=Reactome:REACT_6802, GO:0002755=Reactome:REACT_27215, GO:0034166=Reactome:REACT_9027, GO:0005654=Reactome:REACT_12437, GO:0035666=Reactome:REACT_25281, GO:0034146=Reactome:REACT_9061, GO:0034138=Reactome:REACT_6783, GO:0034162=Reactome:REACT_9047} P18846 Cyclic AMP-dependent transcription factor ATF-1 protein 20130301 {GO:0005667=IEA, GO:0048011=TAS, GO:0038124=TAS, GO:0003700=IEA, GO:0034142=TAS, GO:0038123=TAS, GO:0034134=TAS, GO:0005634=IDA, GO:0002224=TAS, GO:0051403=TAS, GO:0003677=IEA, GO:0006351=IEA, GO:0043565=IEA, GO:0002756=TAS, GO:0045087=TAS, GO:0002755=TAS, GO:0034166=TAS, GO:0005654=TAS, GO:0035666=TAS, GO:0034146=TAS, GO:0034138=TAS, GO:0034162=TAS} MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, innate immune response, neurotrophin TRK receptor signaling pathway, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, transcription, DNA-dependent nucleoplasm, nucleus, transcription factor complex DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human ATF2 HPA UniProtKB {GO:0005515=PMID:22439931, GO:0034142=Reactome:REACT_6894, GO:0003700=GO_REF:0000002, GO:0006366=PMID:19861239, GO:0035497=PMID:19861239, GO:0003705=PMID:19861239, GO:0032915=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0051403=Reactome:REACT_21308, GO:0051090=Reactome:REACT_21326, GO:0002756=Reactome:REACT_6809, GO:0008140=PMID:19861239, GO:0002755=Reactome:REACT_27215, GO:0045444=GO_REF:0000019, GO:0034138=Reactome:REACT_6783, GO:0001102=PMID:19861239, GO:0038124=Reactome:REACT_8006, GO:0006357=PMID:19861239, GO:0038123=Reactome:REACT_8005, GO:0046982=GO_REF:0000019, GO:0019901=PMID:21098032, GO:0034134=Reactome:REACT_7980, GO:0003713=PMID:2529117, GO:0005730=GO_REF:0000052, GO:0006970=PMID:21098032, GO:0003676=GO_REF:0000002, GO:0002224=Reactome:REACT_9020, GO:0003151=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0001077=GO_REF:0000019, GO:0001076=PMID:19861239, GO:0016020=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0003682=GO_REF:0000019, GO:0000980=PMID:19861239, GO:0008270=GO_REF:0000002, GO:0035666=Reactome:REACT_25281, GO:0034166=Reactome:REACT_9027, GO:0005654=Reactome:REACT_6839, GO:0034146=Reactome:REACT_9061, GO:0060612=GO_REF:0000019, GO:0034162=Reactome:REACT_9047} Q3B7B7 Cyclic AMP-dependent transcription factor ATF-2 protein 20100326 {GO:0005515=IPI, GO:0034142=TAS, GO:0003700=IEA, GO:0006366=IC, GO:0035497=IDA, GO:0003705=IC, GO:0032915=IEA, GO:0005634=IDA, GO:0051403=TAS, GO:0051090=TAS, GO:0002756=TAS, GO:0008140=IDA, GO:0002755=TAS, GO:0045444=IEA, GO:0034138=TAS, GO:0001102=IPI, GO:0038124=TAS, GO:0006357=IC, GO:0038123=TAS, GO:0046982=IEA, GO:0019901=IPI, GO:0034134=TAS, GO:0003713=TAS, GO:0005730=IDA, GO:0006970=IDA, GO:0003676=IEA, GO:0002224=TAS, GO:0003151=IEA, GO:0043565=IEA, GO:0001077=IEA, GO:0001076=IC, GO:0016020=IEA, GO:0045087=TAS, GO:0003682=IEA, GO:0000980=IDA, GO:0008270=IEA, GO:0035666=TAS, GO:0034166=TAS, GO:0005654=TAS, GO:0034146=TAS, GO:0060612=IEA, GO:0034162=TAS} MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, adipose tissue development, fat cell differentiation, innate immune response, outflow tract morphogenesis, positive regulation of transforming growth factor beta2 production, regulation of sequence-specific DNA binding transcription factor activity, regulation of transcription from RNA polymerase II promoter, response to osmotic stress, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, transcription from RNA polymerase II promoter membrane, nucleolus, nucleoplasm, nucleus RNA polymerase II activating transcription factor binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II distal enhancer sequence-specific DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, RNA polymerase II transcription factor binding transcription factor activity, cAMP response element binding, cAMP response element binding protein binding, chromatin binding, nucleic acid binding, protein binding, protein heterodimerization activity, protein kinase binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, zinc ion binding NOT Human ATF3 HPA UniProtKB {GO:0005515=PMID:18255255, GO:0008284=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0003714=PMID:7515060, GO:0006950=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0006094=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037, GO:0030968=Reactome:REACT_18356, GO:0042802=PMID:18255255, GO:0043565=GO_REF:0000002, GO:0005654=Reactome:REACT_115743, GO:0006987=Reactome:REACT_18277, GO:0045892=GO_REF:0000019, GO:0044267=Reactome:REACT_17015} Q5VTZ4 Cyclic AMP-dependent transcription factor ATF-3 protein 20080818 {GO:0005515=IPI, GO:0008284=IEA, GO:0003700=IEA, GO:0003714=TAS, GO:0006950=IEA, GO:0005730=IDA, GO:0006094=IEA, GO:0005634=IDA, GO:0006351=IEA, GO:0030968=TAS, GO:0042802=IPI, GO:0043565=IEA, GO:0005654=TAS, GO:0006987=TAS, GO:0045892=IEA, GO:0044267=TAS} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, gluconeogenesis, negative regulation of transcription, DNA-dependent, positive regulation of cell proliferation, response to stress, transcription, DNA-dependent nucleolus, nucleoplasm, nucleus identical protein binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human ATF4 BHF-UCL UniProtKB {GO:0005515=PMID:12812986, GO:0034976=PMID:19061639, GO:0003700=PMID:12689582, GO:0006366=GO_REF:0000024, GO:0006094=GO_REF:0000024, GO:0043267=GO_REF:0000019, GO:0005634=PMID:16682973, GO:0030968=Reactome:REACT_18356, GO:0005737=GO_REF:0000024, GO:0043525=GO_REF:0000024, GO:0045944=PMID:15788408, GO:0005667=GO_REF:0000019, GO:0006520=PMID:12689582, GO:0006355=GO_REF:0000024, GO:0005815=GO_REF:0000039, GO:0007214=GO_REF:0000019, GO:0008022=GO_REF:0000019, GO:0003677=PMID:18940792, GO:0043565=GO_REF:0000002, GO:0032590=GO_REF:0000019, GO:0070059=GO_REF:0000024, GO:0005654=Reactome:REACT_18270, GO:0045893=PMID:15775988, GO:0006987=Reactome:REACT_18277, GO:0044267=Reactome:REACT_17015} P18848 Cyclic AMP-dependent transcription factor ATF-4 protein 20090601 {GO:0005515=IPI, GO:0034976=IDA, GO:0003700=TAS, GO:0006366=ISS, GO:0006094=ISS, GO:0043267=IEA, GO:0005634=IDA, GO:0030968=TAS, GO:0005737=ISS, GO:0043525=ISS, GO:0045944=IMP, GO:0005667=IEA, GO:0006520=TAS, GO:0006355=ISS, GO:0005815=IEA, GO:0007214=IEA, GO:0008022=IEA, GO:0003677=IDA, GO:0043565=IEA, GO:0032590=IEA, GO:0070059=ISS, GO:0005654=TAS, GO:0045893=IDA, GO:0006987=TAS, GO:0044267=TAS} activation of signaling protein activity involved in unfolded protein response, cellular amino acid metabolic process, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, gamma-aminobutyric acid signaling pathway, gluconeogenesis, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, negative regulation of potassium ion transport, positive regulation of neuron apoptotic process, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, response to endoplasmic reticulum stress, transcription from RNA polymerase II promoter cytoplasm, dendrite membrane, microtubule organizing center, nucleoplasm, nucleus, transcription factor complex DNA binding, protein C-terminus binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human ATF5 HPA UniProtKB {GO:0005515=PMID:10373550, GO:0005667=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0006357=GO_REF:0000019, GO:0003714=PMID:10373550, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0048712=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0031072=GO_REF:0000019} Q9Y2D1 Cyclic AMP-dependent transcription factor ATF-5 protein 20101115 {GO:0005515=IPI, GO:0005667=IEA, GO:0043066=IEA, GO:0003700=IEA, GO:0006357=IEA, GO:0003714=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0006351=IEA, GO:0043565=IEA, GO:0048712=IEA, GO:0005737=IDA, GO:0031072=IEA} negative regulation of apoptotic process, negative regulation of astrocyte differentiation, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, nucleolus, nucleus, transcription factor complex heat shock protein binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human ATF6 BHF-UCL UniProtKB {GO:0005515=PMID:16469704, GO:0003700=GO_REF:0000002, GO:0006357=PMID:10564271, GO:0006990=PMID:9837962, GO:0003713=PMID:10866666, GO:0006950=PMID:10866666, GO:0005634=PMID:10564271, GO:0005635=PMID:10866666, GO:0006351=GO_REF:0000037, GO:0030968=PMID:19816510, GO:0043565=GO_REF:0000002, GO:0007165=PMID:9271374, GO:0000139=Reactome:REACT_18431, GO:0006457=PMID:10564271, GO:0005789=Reactome:REACT_18431, GO:0005654=Reactome:REACT_18286, GO:0016021=GO_REF:0000037, GO:0006987=Reactome:REACT_18348, GO:0044267=Reactome:REACT_17015} P18850 Cyclic AMP-dependent transcription factor ATF-6 alpha protein 20100107 {GO:0005515=IPI, GO:0003700=IEA, GO:0006357=TAS, GO:0006990=TAS, GO:0003713=TAS, GO:0006950=TAS, GO:0005634=TAS, GO:0005635=TAS, GO:0006351=IEA, GO:0030968=TAS, GO:0043565=IEA, GO:0007165=TAS, GO:0000139=TAS, GO:0006457=TAS, GO:0005789=TAS, GO:0005654=TAS, GO:0016021=IEA, GO:0006987=TAS, GO:0044267=TAS} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response, protein folding, regulation of transcription from RNA polymerase II promoter, response to stress, signal transduction, transcription, DNA-dependent Golgi membrane, endoplasmic reticulum membrane, integral to membrane, nuclear envelope, nucleoplasm, nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity Human ATF6B HPA UniProtKB {GO:0005622=PMID:8870652, GO:0006986=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0007165=PMID:8586413, GO:0003700=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005789=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0016021=GO_REF:0000037, GO:0005925=GO_REF:0000052, GO:0006351=GO_REF:0000037} Q99941 Cyclic AMP-dependent transcription factor ATF-6 beta protein 20120912 {GO:0005622=IDA, GO:0006986=IEA, GO:0043565=IEA, GO:0007165=TAS, GO:0003700=IEA, GO:0005730=IDA, GO:0005789=IEA, GO:0005634=IDA, GO:0016021=IEA, GO:0005925=IDA, GO:0006351=IEA} response to unfolded protein, signal transduction, transcription, DNA-dependent endoplasmic reticulum membrane, focal adhesion, integral to membrane, intracellular, nucleolus, nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human ATF7 HPA UniProtKB {GO:0005515=PMID:20195357, GO:0006355=PMID:8288576, GO:0003700=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0034399=PMID:17264123, GO:0019048=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0005654=GO_REF:0000039, GO:0051019=PMID:10376527, GO:0008134=PMID:10376527} P17544 Cyclic AMP-dependent transcription factor ATF-7 protein 20101115 {GO:0005515=IPI, GO:0006355=IDA, GO:0003700=IEA, GO:0005634=IDA, GO:0003676=IEA, GO:0006351=IEA, GO:0043565=IEA, GO:0005737=IDA, GO:0034399=IDA, GO:0019048=IEA, GO:0008270=IEA, GO:0005654=IEA, GO:0051019=IDA, GO:0008134=IDA} regulation of transcription, DNA-dependent, transcription, DNA-dependent, virus-host interaction cytoplasm, nuclear periphery, nucleoplasm, nucleus mitogen-activated protein kinase binding, nucleic acid binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, zinc ion binding Human ATF7IP IntAct UniProtKB {GO:0006306=PMID:12665582, GO:0005515=PMID:12812986, GO:0005667=GO_REF:0000019, GO:0045898=PMID:12665582, GO:0019048=GO_REF:0000037, GO:0003714=GO_REF:0000019, GO:0005634=PMID:12665582, GO:0000122=GO_REF:0000019, GO:0045893=PMID:12665582, GO:0045892=PMID:12665582, GO:0016887=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q6VMQ6 Activating transcription factor 7-interacting protein 1 protein 20130415 {GO:0006306=IDA, GO:0005515=IPI, GO:0005667=IEA, GO:0045898=IDA, GO:0019048=IEA, GO:0003714=IEA, GO:0005634=IDA, GO:0000122=IEA, GO:0045893=IDA, GO:0045892=IDA, GO:0016887=IEA, GO:0006351=IEA} DNA methylation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of transcription, DNA-dependent, regulation of RNA polymerase II transcriptional preinitiation complex assembly, transcription, DNA-dependent, virus-host interaction nucleus, transcription factor complex ATPase activity, protein binding, transcription corepressor activity Human UniProtKB:Q9NRI5 ATF7IP2 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037} Q5U623 Activating transcription factor 7-interacting protein 2 protein 20111111 {GO:0005737=IDA, GO:0006355=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleolus, nucleus Human ATG10 LIFEdb UniProtKB {GO:0005622=GO_REF:0000054, GO:0005737=GO_REF:0000039, GO:0019777=PMID:20723759, GO:0006914=PMID:15657430, GO:0006497=GO_REF:0000024, GO:0032446=PMID:16963840, GO:0034263=PMID:17256008, GO:0015031=GO_REF:0000037, GO:0031401=GO_REF:0000024} Q9H0Y0 Ubiquitin-like-conjugating enzyme ATG10 protein 20100607 {GO:0005622=IDA, GO:0005737=IEA, GO:0019777=ISS, GO:0006914=IMP, GO:0006497=ISS, GO:0032446=IDA, GO:0034263=IMP, GO:0015031=IEA, GO:0031401=ISS} autophagy, autophagy in response to ER overload, positive regulation of protein modification process, protein lipidation, protein modification by small protein conjugation, protein transport cytoplasm, intracellular Atg12 ligase activity Human ATG12 Reactome UniProtKB {GO:0005515=PMID:11096062, GO:0043234=GO_REF:0000019, GO:0034045=GO_REF:0000024, GO:0005737=GO_REF:0000002, GO:0045087=Reactome:REACT_6802, GO:0000045=GO_REF:0000024, GO:0032480=Reactome:REACT_25271} O94817 Ubiquitin-like protein ATG12 protein 20100819 {GO:0005515=IPI, GO:0043234=IEA, GO:0034045=ISS, GO:0005737=IEA, GO:0045087=TAS, GO:0000045=ISS, GO:0032480=TAS} autophagic vacuole assembly, innate immune response, negative regulation of type I interferon production cytoplasm, pre-autophagosomal structure membrane, protein complex protein binding Human ATG13 IntAct UniProtKB {GO:0005515=PMID:20562859, GO:0070969=PMID:19211835, GO:0019901=PMID:18936157, GO:0000407=GO_REF:0000024, GO:0000045=PMID:19211835, GO:0005829=GO_REF:0000039} O75143 Autophagy-related protein 13 protein 20130415 {GO:0005515=IPI, GO:0070969=IPI, GO:0019901=IPI, GO:0000407=ISS, GO:0000045=IMP, GO:0005829=IEA} autophagic vacuole assembly ULK1-ATG13-FIP200 complex, cytosol, pre-autophagosomal structure protein binding, protein kinase binding Human UniProtKB:Q9H0R8 ATG14 UniProtKB UniProtKB {GO:0005515=PMID:19270696, GO:0034045=PMID:19270696, GO:0005776=PMID:19270696, GO:0005783=GO_REF:0000039, GO:0000045=PMID:19270696, GO:0010508=GO_REF:0000002} Q6ZNE5 Beclin 1-associated autophagy-related key regulator protein 20100625 {GO:0005515=IPI, GO:0034045=IDA, GO:0005776=IDA, GO:0005783=IEA, GO:0000045=IMP, GO:0010508=IEA} autophagic vacuole assembly, positive regulation of autophagy autophagic vacuole, endoplasmic reticulum, pre-autophagosomal structure membrane protein binding Human UniProtKB:Q99570 ATG16L1 IntAct UniProtKB {GO:0005515=PMID:20562859, GO:0034045=GO_REF:0000039, GO:0005776=PMID:15620219, GO:0000421=GO_REF:0000019, GO:0051260=PMID:15620219, GO:0000045=PMID:15620219, GO:0015031=GO_REF:0000037} Q676U5 Autophagy-related protein 16-1 protein 20130415 {GO:0005515=IPI, GO:0034045=IEA, GO:0005776=ISS, GO:0000421=IEA, GO:0051260=NAS, GO:0000045=NAS, GO:0015031=IEA} autophagic vacuole assembly, protein homooligomerization, protein transport autophagic vacuole, autophagic vacuole membrane, pre-autophagosomal structure membrane protein binding Human UniProtKB:Q9GZQ8 ATG16L2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0006914=GO_REF:0000037, GO:0015031=GO_REF:0000037} Q8NAA4 Autophagy-related protein 16-2 protein 20130413 {GO:0005737=IEA, GO:0006914=IEA, GO:0015031=IEA} autophagy, protein transport cytoplasm Human UniProtKB-SubCell:SL-0086 ATG2A IntAct UniProtKB {GO:0005515=PMID:20562859, GO:0006914=GO_REF:0000002} Q2TAZ0 Autophagy-related protein 2 homolog A protein 20130415 {GO:0005515=IPI, GO:0006914=IEA} autophagy protein binding Human UniProtKB:Q9H0R8 ATG2B InterPro UniProtKB {GO:0006914=GO_REF:0000002} Q96BY7 Autophagy-related protein 2 homolog B protein 20130413 {GO:0006914=IEA} autophagy Human InterPro:IPR026849 ATG3 IntAct UniProtKB {GO:0005515=PMID:20562859, GO:0016567=PMID:11825910, GO:0019787=PMID:11825910, GO:0006612=GO_REF:0000024, GO:0019776=GO_REF:0000024, GO:0019777=GO_REF:0000024, GO:0019899=PMID:11825910, GO:0000045=GO_REF:0000024, GO:0043653=GO_REF:0000024, GO:0006464=PMID:11825910, GO:0000153=PMID:11825910, GO:0005829=PMID:11825910} Q9NT62 Ubiquitin-like-conjugating enzyme ATG3 protein 20130415 {GO:0005515=IPI, GO:0016567=IDA, GO:0019787=IDA, GO:0006612=ISS, GO:0019776=ISS, GO:0019777=ISS, GO:0019899=IPI, GO:0000045=ISS, GO:0043653=ISS, GO:0006464=IDA, GO:0000153=IPI, GO:0005829=IDA} autophagic vacuole assembly, cellular protein modification process, mitochondrial fragmentation involved in apoptotic process, protein targeting to membrane, protein ubiquitination cytoplasmic ubiquitin ligase complex, cytosol Atg12 ligase activity, Atg8 ligase activity, enzyme binding, protein binding, small conjugating protein ligase activity Human UniProtKB:Q9H0R8 ATG4A MGI UniProtKB {GO:0005737=PMID:12446702, GO:0006914=GO_REF:0000037, GO:0006508=PMID:12473658, GO:0008234=PMID:12473658, GO:0015031=GO_REF:0000037} Q8WYN0 Cysteine protease ATG4A protein 20060110 {GO:0005737=ISS, GO:0006914=IEA, GO:0006508=IDA, GO:0008234=IDA, GO:0015031=IEA} autophagy, protein transport, proteolysis cytoplasm cysteine-type peptidase activity Human ATG4B BHF-UCL UniProtKB {GO:0005515=PMID:20562859, GO:0005737=PMID:12446702, GO:0004175=PMID:18387192, GO:0006914=PMID:12446702, GO:0006508=PMID:18387192, GO:0008234=PMID:15169837, GO:0000045=PMID:12446702, GO:0015031=GO_REF:0000037, GO:0010508=PMID:18387192} Q9Y4P1 Cysteine protease ATG4B protein 20130219 {GO:0005515=IPI, GO:0005737=ISS, GO:0004175=IDA, GO:0006914=IGI, GO:0006508=IDA, GO:0008234=IDA, GO:0000045=IGI, GO:0015031=IEA, GO:0010508=IDA} autophagic vacuole assembly, autophagy, positive regulation of autophagy, protein transport, proteolysis cytoplasm cysteine-type peptidase activity, endopeptidase activity, protein binding Human ATG4C UniProtKB UniProtKB {GO:0004197=PMID:12446702, GO:0005737=PMID:12446702, GO:0006612=PMID:12446702, GO:0006914=PMID:12446702, GO:0006508=PMID:12446702, GO:0005576=PMID:12446702, GO:0008233=PMID:12446702, GO:0008234=GO_REF:0000038, GO:0000045=PMID:12446702, GO:0015031=GO_REF:0000038, GO:0005829=PMID:12446702} Q96DT6 Cysteine protease ATG4C protein 20090421 {GO:0004197=IMP, GO:0005737=ISS, GO:0006612=ISS, GO:0006914=IGI, GO:0006508=IDA, GO:0005576=IDA, GO:0008233=IDA, GO:0008234=IEA, GO:0000045=IGI, GO:0015031=IEA, GO:0005829=ISS} autophagic vacuole assembly, autophagy, protein targeting to membrane, protein transport, proteolysis cytoplasm, cytosol, extracellular region cysteine-type endopeptidase activity, cysteine-type peptidase activity, peptidase activity Human UniProtKB:P53867 ATG4D UniProtKB UniProtKB {GO:0004197=PMID:12446702, GO:0005737=GO_REF:0000038, GO:0006914=GO_REF:0000038, GO:0006508=GO_REF:0000038, GO:0008234=GO_REF:0000038, GO:0015031=GO_REF:0000038} Q969K0 Cysteine protease ATG4D protein 20130413 {GO:0004197=ISS, GO:0005737=IEA, GO:0006914=IEA, GO:0006508=IEA, GO:0008234=IEA, GO:0015031=IEA} autophagy, protein transport, proteolysis cytoplasm cysteine-type endopeptidase activity, cysteine-type peptidase activity Human UniProtKB-KW:KW-0653 ATG5 IntAct UniProtKB {GO:0005515=PMID:20562859, GO:0043066=GO_REF:0000019, GO:0060047=GO_REF:0000019, GO:0005776=PMID:15292400, GO:0042493=GO_REF:0000019, GO:0006914=GO_REF:0000024, GO:0006915=GO_REF:0000037, GO:0005737=GO_REF:0000024, GO:0034045=GO_REF:0000024, GO:0001974=GO_REF:0000019, GO:0048840=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0042311=GO_REF:0000019, GO:0055015=GO_REF:0000019, GO:0031397=GO_REF:0000019, GO:0000045=GO_REF:0000024, GO:0032480=Reactome:REACT_25271, GO:0043687=GO_REF:0000024} Q9H1Y0 Autophagy protein 5 protein 20130415 {GO:0005515=IPI, GO:0043066=IEA, GO:0060047=IEA, GO:0005776=IDA, GO:0042493=IEA, GO:0006914=ISS, GO:0006915=IEA, GO:0005737=ISS, GO:0034045=ISS, GO:0001974=IEA, GO:0048840=IEA, GO:0045087=TAS, GO:0042311=IEA, GO:0055015=IEA, GO:0031397=IEA, GO:0000045=ISS, GO:0032480=TAS, GO:0043687=ISS} apoptotic process, autophagic vacuole assembly, autophagy, blood vessel remodeling, heart contraction, innate immune response, negative regulation of apoptotic process, negative regulation of protein ubiquitination, negative regulation of type I interferon production, otolith development, post-translational protein modification, response to drug, vasodilation, ventricular cardiac muscle cell development autophagic vacuole, cytoplasm, pre-autophagosomal structure membrane protein binding Human UniProtKB:Q9GZQ8 ATG7 BHF-UCL UniProtKB {GO:0005515=PMID:21903422, GO:0021987=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0021860=GO_REF:0000019, GO:0042803=PMID:11096062, GO:0031401=PMID:12890687, GO:0030163=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0042594=GO_REF:0000019, GO:0021680=GO_REF:0000019, GO:0006497=PMID:12890687, GO:0007628=GO_REF:0000019, GO:0031396=GO_REF:0000019, GO:0016239=PMID:22354037, GO:0006520=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0006996=GO_REF:0000019, GO:0021955=GO_REF:0000019, GO:0006914=GO_REF:0000019, GO:0004839=GO_REF:0000019, GO:0032446=GO_REF:0000019, GO:0001889=GO_REF:0000019, GO:0006944=PMID:10233149, GO:0019778=PMID:20723759, GO:0050877=GO_REF:0000019, GO:0055013=GO_REF:0000019, GO:0006464=PMID:10233149, GO:0016044=GO_REF:0000019} O95352 Ubiquitin-like modifier-activating enzyme ATG7 protein 20120531 {GO:0005515=IPI, GO:0021987=IEA, GO:0009791=IEA, GO:0015031=IEA, GO:0021860=IEA, GO:0042803=IDA, GO:0031401=IDA, GO:0030163=IEA, GO:0005737=IDA, GO:0042594=IEA, GO:0021680=IEA, GO:0006497=IDA, GO:0007628=IEA, GO:0031396=IEA, GO:0016239=IMP, GO:0006520=IEA, GO:0043066=IEA, GO:0006996=IEA, GO:0021955=IEA, GO:0006914=IEA, GO:0004839=IEA, GO:0032446=IEA, GO:0001889=IEA, GO:0006944=TAS, GO:0019778=ISS, GO:0050877=IEA, GO:0055013=IEA, GO:0006464=TAS, GO:0016044=IEA} adult walking behavior, autophagy, cardiac muscle cell development, cellular amino acid metabolic process, cellular membrane fusion, cellular membrane organization, cellular protein modification process, central nervous system neuron axonogenesis, cerebellar Purkinje cell layer development, cerebral cortex development, liver development, negative regulation of apoptotic process, neurological system process, organelle organization, positive regulation of macroautophagy, positive regulation of protein modification process, post-embryonic development, protein catabolic process, protein lipidation, protein modification by small protein conjugation, protein transport, pyramidal neuron development, regulation of protein ubiquitination, response to starvation cytoplasm APG12 activating enzyme activity, protein binding, protein homodimerization activity, ubiquitin activating enzyme activity Human ATG9A IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0005776=GO_REF:0000019, GO:0005794=GO_REF:0000039, GO:0005770=GO_REF:0000019, GO:0000421=GO_REF:0000039, GO:0006914=GO_REF:0000019, GO:0031410=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0034067=GO_REF:0000019, GO:0045087=GO_REF:0000019, GO:0031902=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0000045=PMID:15755735} Q7Z3C6 Autophagy-related protein 9A protein 20130415 {GO:0005515=IPI, GO:0005776=IEA, GO:0005794=IEA, GO:0005770=IEA, GO:0000421=IEA, GO:0006914=IEA, GO:0031410=IEA, GO:0015031=IEA, GO:0034067=IEA, GO:0045087=IEA, GO:0031902=IEA, GO:0016021=IEA, GO:0000045=IMP} autophagic vacuole assembly, autophagy, innate immune response, protein localization to Golgi apparatus, protein transport Golgi apparatus, autophagic vacuole, autophagic vacuole membrane, cytoplasmic vesicle, integral to membrane, late endosome, late endosome membrane protein binding Human UniProtKB:Q9UHD2 ATG9B MGI UniProtKB {GO:0000421=GO_REF:0000039, GO:0031410=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0000045=PMID:15755735} Q674R7 Autophagy-related protein 9B protein 20060210 {GO:0000421=IEA, GO:0031410=IEA, GO:0016021=IEA, GO:0000045=IDA} autophagic vacuole assembly autophagic vacuole membrane, cytoplasmic vesicle, integral to membrane Human ATHL1 UniProtKB UniProtKB {GO:0005975=GO_REF:0000002, GO:0016798=GO_REF:0000037, GO:0003824=GO_REF:0000002} Q32M88 Acid trehalase-like protein 1 protein 20130413 {GO:0005975=IEA, GO:0016798=IEA, GO:0003824=IEA} carbohydrate metabolic process catalytic activity, hydrolase activity, acting on glycosyl bonds Human UniProtKB-KW:KW-0326 ATIC Reactome UniProtKB {GO:0009168=Reactome:REACT_1776, GO:0021987=GO_REF:0000019, GO:0003360=GO_REF:0000019, GO:0003937=Reactome:REACT_263, GO:0031100=GO_REF:0000019, GO:0055086=Reactome:REACT_1698, GO:0021549=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0042803=PMID:14966129, GO:0005829=Reactome:REACT_812, GO:0005739=GO_REF:0000019, GO:0004643=Reactome:REACT_812, GO:0006139=PMID:8567683, GO:0046452=GO_REF:0000019, GO:0010035=GO_REF:0000019, GO:0006144=Reactome:REACT_522, GO:0009116=GO_REF:0000019, GO:0046654=GO_REF:0000019, GO:0009259=GO_REF:0000019, GO:0006189=GO_REF:0000041, GO:0006164=GO_REF:0000002} P31939 Bifunctional purine biosynthesis protein PURH protein 20130213 {GO:0009168=TAS, GO:0021987=IEA, GO:0003360=IEA, GO:0003937=TAS, GO:0031100=IEA, GO:0055086=TAS, GO:0021549=IEA, GO:0044281=TAS, GO:0042803=IPI, GO:0005829=TAS, GO:0005739=IEA, GO:0004643=TAS, GO:0006139=TAS, GO:0046452=IEA, GO:0010035=IEA, GO:0006144=TAS, GO:0009116=IEA, GO:0046654=IEA, GO:0009259=IEA, GO:0006189=IEA, GO:0006164=IEA} 'de novo' IMP biosynthetic process, brainstem development, cerebellum development, cerebral cortex development, dihydrofolate metabolic process, nucleobase-containing compound metabolic process, nucleobase-containing small molecule metabolic process, nucleoside metabolic process, organ regeneration, purine nucleobase metabolic process, purine nucleotide biosynthetic process, purine ribonucleoside monophosphate biosynthetic process, response to inorganic substance, ribonucleotide metabolic process, small molecule metabolic process, tetrahydrofolate biosynthetic process cytosol, mitochondrion IMP cyclohydrolase activity, phosphoribosylaminoimidazolecarboxamide formyltransferase activity, protein homodimerization activity Human ATL1 GOC UniProtKB {GO:0005515=PMID:19665976, GO:0008219=GO_REF:0000037, GO:0030424=GO_REF:0000039, GO:0005794=GO_REF:0000024, GO:0005783=PMID:19665976, GO:0003924=PMID:14506257, GO:0007409=GO_REF:0000024, GO:0005525=GO_REF:0000024, GO:0042802=PMID:14506257, GO:0006184=PMID:14506257, GO:0000137=GO_REF:0000024, GO:0000139=GO_REF:0000039, GO:0005789=GO_REF:0000024, GO:0051260=PMID:14506257, GO:0016021=PMID:14506257, GO:0007029=PMID:19665976} Q8WXF7 Atlastin-1 protein 20130413 {GO:0005515=IPI, GO:0008219=IEA, GO:0030424=IEA, GO:0005794=ISS, GO:0005783=IDA, GO:0003924=IDA, GO:0007409=ISS, GO:0005525=ISS, GO:0042802=IDA, GO:0006184=IDA, GO:0000137=ISS, GO:0000139=IEA, GO:0005789=ISS, GO:0051260=IDA, GO:0016021=IDA, GO:0007029=IDA} GTP catabolic process, axonogenesis, cell death, endoplasmic reticulum organization, protein homooligomerization Golgi apparatus, Golgi cis cisterna, Golgi membrane, axon, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane GTP binding, GTPase activity, identical protein binding, protein binding Human ATL2 GOC UniProtKB {GO:0006184=PMID:18270207, GO:0006888=PMID:18270207, GO:0005515=PMID:19665976, GO:0005783=PMID:18270207, GO:0007030=PMID:18270207, GO:0005789=GO_REF:0000039, GO:0003924=PMID:18270207, GO:0051260=PMID:18270207, GO:0016021=PMID:18270207, GO:0005525=GO_REF:0000037, GO:0007029=PMID:19665976, GO:0042802=PMID:18270207} Q8NHH9 Atlastin-2 protein 20130413 {GO:0006184=NAS, GO:0006888=IMP, GO:0005515=IPI, GO:0005783=IDA, GO:0007030=IMP, GO:0005789=IEA, GO:0003924=NAS, GO:0051260=IDA, GO:0016021=IDA, GO:0005525=IEA, GO:0007029=IMP, GO:0042802=IDA} ER to Golgi vesicle-mediated transport, GTP catabolic process, Golgi organization, endoplasmic reticulum organization, protein homooligomerization endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane GTP binding, GTPase activity, identical protein binding, protein binding Human ATL3 GOC UniProtKB {GO:0006184=PMID:18270207, GO:0006888=PMID:18270207, GO:0005783=PMID:18270207, GO:0007030=PMID:18270207, GO:0005789=GO_REF:0000039, GO:0003924=PMID:18270207, GO:0051260=PMID:18270207, GO:0016021=PMID:18270207, GO:0005525=GO_REF:0000037, GO:0007029=PMID:19665976, GO:0042802=PMID:18270207} Q6DD88 Atlastin-3 protein 20130413 {GO:0006184=NAS, GO:0006888=IMP, GO:0005783=IDA, GO:0007030=IMP, GO:0005789=IEA, GO:0003924=NAS, GO:0051260=IDA, GO:0016021=IDA, GO:0005525=IEA, GO:0007029=IMP, GO:0042802=IDA} ER to Golgi vesicle-mediated transport, GTP catabolic process, Golgi organization, endoplasmic reticulum organization, protein homooligomerization endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane GTP binding, GTPase activity, identical protein binding Human ATM GOC UniProtKB {GO:0005515=PMID:20810650, GO:0002331=GO_REF:0000024, GO:0001756=GO_REF:0000019, GO:0004677=PMID:15790808, GO:0051402=GO_REF:0000019, GO:0032403=PMID:15790808, GO:0007507=GO_REF:0000019, GO:0043525=GO_REF:0000019, GO:0046777=PMID:9733515, GO:0018105=PMID:9733515, GO:0016303=PMID:11375976, GO:0046983=PMID:15790808, GO:0007131=PMID:7792600, GO:0006977=Reactome:REACT_1625, GO:0000781=PMID:15149599, GO:0036092=PMID:11375976, GO:0005819=GO_REF:0000019, GO:0030889=PMID:17875758, GO:0035174=GO_REF:0000019, GO:0006281=Reactome:REACT_216, GO:0007420=GO_REF:0000019, GO:0071044=PMID:16086026, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_20543, GO:0000077=GO_REF:0000002, GO:0090399=PMID:15149599, GO:0042159=GO_REF:0000019, GO:0007094=PMID:11943150, GO:0031572=PMID:15149599, GO:0005634=GO_REF:0000019, GO:0071480=PMID:9925639, GO:0006302=Reactome:REACT_2054, GO:0005737=GO_REF:0000019, GO:0000723=GO_REF:0000002, GO:0000724=Reactome:REACT_1874, GO:0010212=PMID:9733515, GO:0051726=GO_REF:0000019, GO:0007050=PMID:15149599, GO:0001666=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0043065=PMID:17875758, GO:0008630=GO_REF:0000019, GO:0016572=GO_REF:0000002, GO:0007292=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0006974=PMID:15790808, GO:0006975=PMID:9733515, GO:0007165=PMID:7792600, GO:0047485=PMID:11375976, GO:0004674=PMID:9733515, GO:0043517=PMID:9733515, GO:0016023=GO_REF:0000039} Q13315 Serine-protein kinase ATM protein 20130413 {GO:0005515=IPI, GO:0002331=ISS, GO:0001756=IEA, GO:0004677=IDA, GO:0051402=IEA, GO:0032403=IDA, GO:0007507=IEA, GO:0043525=IEA, GO:0046777=IDA, GO:0018105=IDA, GO:0016303=IMP, GO:0046983=IDA, GO:0007131=TAS, GO:0006977=TAS, GO:0000781=IDA, GO:0036092=IMP, GO:0005819=IEA, GO:0030889=IMP, GO:0035174=IEA, GO:0006281=TAS, GO:0007420=IEA, GO:0071044=IDA, GO:0000075=TAS, GO:0005654=TAS, GO:0000077=IEA, GO:0090399=IMP, GO:0042159=IEA, GO:0007094=IMP, GO:0031572=IMP, GO:0005634=IEA, GO:0071480=IDA, GO:0006302=TAS, GO:0005737=IEA, GO:0000723=IEA, GO:0000724=TAS, GO:0010212=IDA, GO:0051726=IEA, GO:0007050=IMP, GO:0001666=IEA, GO:0043066=IEA, GO:0043065=IMP, GO:0008630=IEA, GO:0016572=IEA, GO:0007292=IEA, GO:0003677=IEA, GO:0005524=IEA, GO:0006974=IMP, GO:0006975=IDA, GO:0007165=TAS, GO:0047485=IDA, GO:0004674=IDA, GO:0043517=IMP, GO:0016023=IEA} DNA damage checkpoint, DNA damage induced protein phosphorylation, DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, DNA repair, G2 DNA damage checkpoint, brain development, cell cycle arrest, cell cycle checkpoint, cellular response to gamma radiation, double-strand break repair, double-strand break repair via homologous recombination, female gamete generation, heart development, histone mRNA catabolic process, histone phosphorylation, intrinsic apoptotic signaling pathway in response to DNA damage, lipoprotein catabolic process, mitotic spindle assembly checkpoint, negative regulation of B cell proliferation, negative regulation of apoptotic process, neuron apoptotic process, peptidyl-serine phosphorylation, phosphatidylinositol-3-phosphate biosynthetic process, positive regulation of DNA damage response, signal transduction by p53 class mediator, positive regulation of apoptotic process, positive regulation of neuron apoptotic process, pre-B cell allelic exclusion, protein autophosphorylation, reciprocal meiotic recombination, regulation of cell cycle, replicative senescence, response to DNA damage stimulus, response to hypoxia, response to ionizing radiation, signal transduction, somitogenesis, telomere maintenance chromosome, telomeric region, cytoplasm, cytoplasmic membrane-bounded vesicle, nucleoplasm, nucleus, spindle 1-phosphatidylinositol-3-kinase activity, ATP binding, DNA binding, DNA-dependent protein kinase activity, histone serine kinase activity, protein N-terminus binding, protein binding, protein complex binding, protein dimerization activity, protein serine/threonine kinase activity Human ATMIN UniProtKB UniProtKB {GO:0045502=PMID:22167198, GO:0044212=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0045893=PMID:22167198, GO:0006974=GO_REF:0000037, GO:0006351=GO_REF:0000037} O43313 ATM interactor protein 20120706 {GO:0045502=IPI, GO:0044212=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0045893=IDA, GO:0006974=IEA, GO:0006351=IEA} positive regulation of transcription, DNA-dependent, response to DNA damage stimulus, transcription, DNA-dependent nucleus dynein binding, transcription regulatory region DNA binding, zinc ion binding Human UniProtKB:P63167 ATN1 IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0048471=GO_REF:0000039, GO:0030054=GO_REF:0000039, GO:0003714=PMID:10973986, GO:0019904=PMID:11984006, GO:0005634=PMID:10085113, GO:0030011=GO_REF:0000019, GO:0000122=PMID:10973986, GO:0007417=PMID:7647802, GO:0051402=PMID:10085113, GO:0016363=PMID:10973986, GO:0006351=GO_REF:0000037, GO:0005737=PMID:7647802, GO:0050827=GO_REF:0000019, GO:0016477=GO_REF:0000019, GO:0009404=GO_REF:0000019} P54259 Atrophin-1 protein 20130415 {GO:0005515=IPI, GO:0048471=IEA, GO:0030054=IEA, GO:0003714=IDA, GO:0019904=IPI, GO:0005634=IDA, GO:0030011=IEA, GO:0000122=IDA, GO:0007417=TAS, GO:0051402=IDA, GO:0016363=IDA, GO:0006351=IEA, GO:0005737=TAS, GO:0050827=IEA, GO:0016477=IEA, GO:0009404=IEA} cell migration, central nervous system development, maintenance of cell polarity, negative regulation of transcription from RNA polymerase II promoter, neuron apoptotic process, toxin metabolic process, transcription, DNA-dependent cell junction, cytoplasm, nuclear matrix, nucleus, perinuclear region of cytoplasm protein binding, protein domain specific binding, toxin receptor binding, transcription corepressor activity Human UniProtKB:Q9P2R6 ATOH1 PINC UniProtKB {GO:0042668=GO_REF:0000019, GO:0003700=PMID:8872459, GO:0021987=GO_REF:0000019, GO:0042472=GO_REF:0000019, GO:0006366=PMID:8872459, GO:0006915=GO_REF:0000019, GO:0005634=GO_REF:0000024, GO:0007417=PMID:8872459, GO:0042667=GO_REF:0000019, GO:0031490=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0045666=GO_REF:0000024, GO:0045944=GO_REF:0000019, GO:0045609=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0001764=GO_REF:0000019} Q92858 Protein atonal homolog 1 protein 20030904 {GO:0042668=IEA, GO:0003700=TAS, GO:0021987=IEA, GO:0042472=IEA, GO:0006366=TAS, GO:0006915=IEA, GO:0005634=ISS, GO:0007417=TAS, GO:0042667=IEA, GO:0031490=IEA, GO:0043565=IEA, GO:0007411=IEA, GO:0045666=ISS, GO:0045944=IEA, GO:0045609=IEA, GO:0046983=IEA, GO:0001764=IEA} apoptotic process, auditory receptor cell fate determination, auditory receptor cell fate specification, axon guidance, central nervous system development, cerebral cortex development, inner ear morphogenesis, neuron migration, positive regulation of auditory receptor cell differentiation, positive regulation of neuron differentiation, positive regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter nucleus chromatin DNA binding, protein dimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human ATOH8 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0007399=GO_REF:0000037} Q96SQ7 Protein atonal homolog 8 protein 20130413 {GO:0006355=IEA, GO:0046983=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0030154=IEA, GO:0006351=IEA, GO:0007399=IEA} cell differentiation, nervous system development, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, protein dimerization activity Human UniProtKB-SubCell:SL-0191 ATOX1 UniProtKB UniProtKB {GO:0032767=PMID:10497213, GO:0006878=GO_REF:0000019, GO:0005507=PMID:12029094, GO:0016531=PMID:12029094, GO:0016530=PMID:15670166, GO:0006979=GO_REF:0000019, GO:0046872=GO_REF:0000002, GO:0030001=GO_REF:0000002, GO:0006825=PMID:15670166, GO:0005829=PMID:12029094} O00244 Copper transport protein ATOX1 protein 20061212 {GO:0032767=IPI, GO:0006878=IEA, GO:0005507=IDA, GO:0016531=IDA, GO:0016530=TAS, GO:0006979=IEA, GO:0046872=IEA, GO:0030001=IEA, GO:0006825=TAS, GO:0005829=TAS} cellular copper ion homeostasis, copper ion transport, metal ion transport, response to oxidative stress cytosol copper chaperone activity, copper ion binding, copper-dependent protein binding, metal ion binding, metallochaperone activity Human UniProtKB:Q04656 ATP10D Reactome UniProtKB {GO:0005515=PMID:21914794, GO:0000287=PMID:12532265, GO:0005886=Reactome:REACT_115892, GO:0005783=PMID:21914794, GO:0005524=PMID:12532265, GO:0055085=Reactome:REACT_15518, GO:0045332=PMID:21914794, GO:0019829=GO_REF:0000002, GO:0034220=Reactome:REACT_25300, GO:0004012=PMID:12532265, GO:0005789=GO_REF:0000039, GO:0016021=PMID:12532265, GO:0006812=PMID:12532265} Q9P241 Probable phospholipid-transporting ATPase VD protein 20130301 {GO:0005515=IPI, GO:0000287=NAS, GO:0005886=TAS, GO:0005783=IDA, GO:0005524=NAS, GO:0055085=TAS, GO:0045332=NAS, GO:0019829=IEA, GO:0034220=TAS, GO:0004012=NAS, GO:0005789=IEA, GO:0016021=NAS, GO:0006812=NAS} cation transport, ion transmembrane transport, phospholipid translocation, transmembrane transport endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, plasma membrane ATP binding, cation-transporting ATPase activity, magnesium ion binding, phospholipid-translocating ATPase activity, protein binding Human ATP11A UniProtKB UniProtKB {GO:0005515=PMID:21914794, GO:0019829=GO_REF:0000002, GO:0000287=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0005783=PMID:21914794, GO:0004012=GO_REF:0000003, GO:0016021=GO_REF:0000037, GO:0055037=PMID:21914794, GO:0005524=GO_REF:0000037, GO:0045332=PMID:21914794, GO:0005769=GO_REF:0000039} P98196 Probable phospholipid-transporting ATPase IH protein 20110922 {GO:0005515=IPI, GO:0019829=IEA, GO:0000287=IEA, GO:0005886=IEA, GO:0005783=IDA, GO:0004012=IEA, GO:0016021=IEA, GO:0055037=IDA, GO:0005524=IEA, GO:0045332=NAS, GO:0005769=IEA} phospholipid translocation early endosome, endoplasmic reticulum, integral to membrane, plasma membrane, recycling endosome ATP binding, cation-transporting ATPase activity, magnesium ion binding, phospholipid-translocating ATPase activity, protein binding Human ATP11B Reactome UniProtKB {GO:0005515=PMID:21914794, GO:0000287=GO_REF:0000002, GO:0005886=Reactome:REACT_115892, GO:0005783=PMID:21914794, GO:0015075=PMID:11790799, GO:0005637=PMID:11790799, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0045332=PMID:21914794, GO:0019829=GO_REF:0000002, GO:0034220=Reactome:REACT_25300, GO:0004012=PMID:11015572, GO:0016021=GO_REF:0000037, GO:0015917=PMID:11015572, GO:0055037=PMID:21914794, GO:0055038=GO_REF:0000039, GO:0005769=GO_REF:0000039, GO:0006811=PMID:11790799} Q9Y2G3 Probable phospholipid-transporting ATPase IF protein 20130301 {GO:0005515=IPI, GO:0000287=IEA, GO:0005886=TAS, GO:0005783=IDA, GO:0015075=NAS, GO:0005637=NAS, GO:0055085=TAS, GO:0005524=IEA, GO:0045332=NAS, GO:0019829=IEA, GO:0034220=TAS, GO:0004012=TAS, GO:0016021=IEA, GO:0015917=TAS, GO:0055037=IDA, GO:0055038=IEA, GO:0005769=IEA, GO:0006811=NAS} aminophospholipid transport, ion transmembrane transport, ion transport, phospholipid translocation, transmembrane transport early endosome, endoplasmic reticulum, integral to membrane, nuclear inner membrane, plasma membrane, recycling endosome, recycling endosome membrane ATP binding, cation-transporting ATPase activity, ion transmembrane transporter activity, magnesium ion binding, phospholipid-translocating ATPase activity, protein binding Human ATP11C Reactome UniProtKB {GO:0005515=PMID:21914794, GO:0019829=GO_REF:0000002, GO:0034220=Reactome:REACT_25300, GO:0000287=GO_REF:0000002, GO:0005886=Reactome:REACT_115892, GO:0005783=PMID:21914794, GO:0004012=GO_REF:0000003, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0045332=PMID:21914794} Q8NB49 Probable phospholipid-transporting ATPase IG protein 20130301 {GO:0005515=IPI, GO:0019829=IEA, GO:0034220=TAS, GO:0000287=IEA, GO:0005886=TAS, GO:0005783=IDA, GO:0004012=IEA, GO:0005789=IEA, GO:0016021=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0045332=NAS} ion transmembrane transport, phospholipid translocation, transmembrane transport endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, plasma membrane ATP binding, cation-transporting ATPase activity, magnesium ion binding, phospholipid-translocating ATPase activity, protein binding Human ATP12A Reactome UniProtKB {GO:0016323=GO_REF:0000019, GO:0006754=GO_REF:0000002, GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_25173, GO:0005889=PMID:8838794, GO:0055075=GO_REF:0000019, GO:0008900=GO_REF:0000003, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0006885=GO_REF:0000019, GO:0046872=GO_REF:0000037} P54707 Potassium-transporting ATPase alpha chain 2 protein 20130301 {GO:0016323=IEA, GO:0006754=IEA, GO:0034220=TAS, GO:0005886=TAS, GO:0005889=TAS, GO:0055075=IEA, GO:0008900=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0006885=IEA, GO:0046872=IEA} ATP biosynthetic process, ion transmembrane transport, potassium ion homeostasis, regulation of pH, transmembrane transport basolateral plasma membrane, hydrogen:potassium-exchanging ATPase complex, plasma membrane ATP binding, hydrogen:potassium-exchanging ATPase activity, metal ion binding Human ATP13A1 BHF-UCL UniProtKB {GO:0019829=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q9HD20 Probable cation-transporting ATPase 13A1 protein 20090331 {GO:0019829=IEA, GO:0003674=ND, GO:0008150=ND, GO:0005575=ND, GO:0016021=IEA, GO:0005524=IEA, GO:0046872=IEA} biological_process cellular_component, integral to membrane ATP binding, cation-transporting ATPase activity, metal ion binding, molecular_function Human ATP13A2 IntAct UniProtKB {GO:0005515=PMID:22645275, GO:0019829=GO_REF:0000002, GO:0000166=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005764=PMID:21542062, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q9NQ11 Probable cation-transporting ATPase 13A2 protein 20130415 {GO:0005515=IPI, GO:0019829=IEA, GO:0000166=IEA, GO:0016021=IEA, GO:0005764=IDA, GO:0005524=IEA, GO:0046872=IEA} integral to membrane, lysosome ATP binding, cation-transporting ATPase activity, metal ion binding, nucleotide binding, protein binding Human UniProtKB:Q9UBN7 ATP13A3 UniProtKB UniProtKB {GO:0019829=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q9H7F0 Probable cation-transporting ATPase 13A3 protein 20130413 {GO:0019829=IEA, GO:0016021=IEA, GO:0005524=IEA, GO:0046872=IEA} integral to membrane ATP binding, cation-transporting ATPase activity, metal ion binding Human UniProtKB-KW:KW-0479 ATP13A4 UniProtKB UniProtKB {GO:0019829=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q4VNC1 Probable cation-transporting ATPase 13A4 protein 20130413 {GO:0019829=IEA, GO:0016021=IEA, GO:0005524=IEA, GO:0046872=IEA} integral to membrane ATP binding, cation-transporting ATPase activity, metal ion binding Human UniProtKB-KW:KW-0479 ATP1A1 InterPro UniProtKB {GO:0005515=PMID:11027149, GO:0005886=Reactome:REACT_25287, GO:0005783=GO_REF:0000019, GO:0003869=GO_REF:0000019, GO:0051087=GO_REF:0000019, GO:0031402=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0016323=GO_REF:0000019, GO:0006754=GO_REF:0000002, GO:0034220=Reactome:REACT_25300, GO:0045989=GO_REF:0000019, GO:0045822=GO_REF:0000019, GO:0086004=GO_REF:0000019, GO:0045823=GO_REF:0000019, GO:0005391=GO_REF:0000019, GO:0042470=GO_REF:0000039, GO:0005794=GO_REF:0000019, GO:0019901=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0030506=GO_REF:0000019, GO:0010107=GO_REF:0000019, GO:0030315=GO_REF:0000019, GO:0030955=GO_REF:0000019, GO:0005890=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000019, GO:0019829=GO_REF:0000002, GO:0060081=GO_REF:0000019, GO:0016020=PMID:1975705, GO:0043531=GO_REF:0000019, GO:0002026=GO_REF:0000019, GO:0005901=GO_REF:0000019, GO:0002028=GO_REF:0000019, GO:0008217=GO_REF:0000019, GO:0031947=GO_REF:0000019, GO:0016021=GO_REF:0000002, GO:0071260=GO_REF:0000019, GO:0005768=GO_REF:0000019, GO:0043548=GO_REF:0000019} Q5TC05 Sodium/potassium-transporting ATPase subunit alpha-1 protein 20130413 {GO:0005515=IPI, GO:0005886=TAS, GO:0005783=IEA, GO:0003869=IEA, GO:0051087=IEA, GO:0031402=IEA, GO:0046872=IEA, GO:0016323=IEA, GO:0006754=IEA, GO:0034220=TAS, GO:0045989=IEA, GO:0045822=IEA, GO:0086004=IEA, GO:0045823=IEA, GO:0005391=IEA, GO:0042470=IEA, GO:0005794=IEA, GO:0019901=IEA, GO:0042493=IEA, GO:0019904=IEA, GO:0030506=IEA, GO:0010107=IEA, GO:0030315=IEA, GO:0030955=IEA, GO:0005890=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0019829=IEA, GO:0060081=IEA, GO:0016020=TAS, GO:0043531=IEA, GO:0002026=IEA, GO:0005901=IEA, GO:0002028=IEA, GO:0008217=IEA, GO:0031947=IEA, GO:0016021=IEA, GO:0071260=IEA, GO:0005768=IEA, GO:0043548=IEA} ATP biosynthetic process, cellular response to mechanical stimulus, ion transmembrane transport, membrane hyperpolarization, negative regulation of glucocorticoid biosynthetic process, negative regulation of heart contraction, positive regulation of heart contraction, positive regulation of striated muscle contraction, potassium ion import, regulation of blood pressure, regulation of cardiac muscle cell contraction, regulation of sodium ion transport, regulation of the force of heart contraction, response to drug, transmembrane transport Golgi apparatus, T-tubule, basolateral plasma membrane, caveola, endoplasmic reticulum, endosome, integral to membrane, melanosome, membrane, plasma membrane, sodium:potassium-exchanging ATPase complex 4-nitrophenylphosphatase activity, ADP binding, ATP binding, ankyrin binding, cation-transporting ATPase activity, chaperone binding, metal ion binding, phosphatidylinositol 3-kinase binding, potassium ion binding, protein binding, protein domain specific binding, protein kinase binding, sodium ion binding, sodium:potassium-exchanging ATPase activity Human InterPro:IPR001757 ATP1A2 Reactome UniProtKB {GO:0008344=GO_REF:0000019, GO:0005886=Reactome:REACT_25287, GO:0015077=GO_REF:0000002, GO:0006942=PMID:10642400, GO:0045202=GO_REF:0000019, GO:0006940=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0019229=GO_REF:0000019, GO:0040011=GO_REF:0000019, GO:0005737=PMID:12539047, GO:0002087=GO_REF:0000019, GO:0006754=GO_REF:0000002, GO:0034220=Reactome:REACT_25300, GO:0043197=GO_REF:0000019, GO:0045988=GO_REF:0000019, GO:0006814=PMID:10642400, GO:0006813=PMID:10642400, GO:0045822=GO_REF:0000019, GO:0086004=GO_REF:0000019, GO:0005391=PMID:12539047, GO:0051481=GO_REF:0000019, GO:0030315=GO_REF:0000019, GO:0005890=PMID:12539047, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000019, GO:0019829=GO_REF:0000002, GO:0002026=GO_REF:0000019, GO:0005901=GO_REF:0000019, GO:0008542=GO_REF:0000019, GO:0001504=GO_REF:0000019, GO:0008217=GO_REF:0000019, GO:0015991=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0071260=GO_REF:0000019, GO:0005768=GO_REF:0000019, GO:0035094=GO_REF:0000019} P50993 Sodium/potassium-transporting ATPase subunit alpha-2 protein 20130301 {GO:0008344=IEA, GO:0005886=TAS, GO:0015077=IEA, GO:0006942=NAS, GO:0045202=IEA, GO:0006940=IEA, GO:0046872=IEA, GO:0019229=IEA, GO:0040011=IEA, GO:0005737=IDA, GO:0002087=IEA, GO:0006754=IEA, GO:0034220=TAS, GO:0043197=IEA, GO:0045988=IEA, GO:0006814=NAS, GO:0006813=NAS, GO:0045822=IEA, GO:0086004=IEA, GO:0005391=IMP, GO:0051481=IEA, GO:0030315=IEA, GO:0005890=IC, GO:0055085=TAS, GO:0005524=IEA, GO:0019829=IEA, GO:0002026=IEA, GO:0005901=IEA, GO:0008542=IEA, GO:0001504=IEA, GO:0008217=IEA, GO:0015991=IEA, GO:0016021=IEA, GO:0071260=IEA, GO:0005768=IEA, GO:0035094=IEA} ATP biosynthetic process, ATP hydrolysis coupled proton transport, adult locomotory behavior, cellular response to mechanical stimulus, ion transmembrane transport, locomotion, negative regulation of heart contraction, negative regulation of striated muscle contraction, neurotransmitter uptake, potassium ion transport, reduction of cytosolic calcium ion concentration, regulation of blood pressure, regulation of cardiac muscle cell contraction, regulation of respiratory gaseous exchange by neurological system process, regulation of smooth muscle contraction, regulation of striated muscle contraction, regulation of the force of heart contraction, regulation of vasoconstriction, response to nicotine, sodium ion transport, transmembrane transport, visual learning T-tubule, caveola, cytoplasm, dendritic spine, endosome, integral to membrane, plasma membrane, sodium:potassium-exchanging ATPase complex, synapse ATP binding, cation-transporting ATPase activity, metal ion binding, monovalent inorganic cation transmembrane transporter activity, sodium:potassium-exchanging ATPase activity Human ATP1A3 Reactome UniProtKB {GO:0008344=GO_REF:0000019, GO:0030424=GO_REF:0000019, GO:0005794=PMID:15260953, GO:0005886=Reactome:REACT_25287, GO:0005783=PMID:15260953, GO:0042493=GO_REF:0000019, GO:0015077=GO_REF:0000002, GO:0045202=GO_REF:0000024, GO:0005634=GO_REF:0000019, GO:0005890=PMID:15260953, GO:0055085=Reactome:REACT_15518, GO:0005524=PMID:15260953, GO:0046872=GO_REF:0000037, GO:0019829=GO_REF:0000002, GO:0006754=GO_REF:0000002, GO:0035235=GO_REF:0000019, GO:0034220=Reactome:REACT_25300, GO:0000166=GO_REF:0000002, GO:0043209=GO_REF:0000019, GO:0008542=GO_REF:0000019, GO:0007613=GO_REF:0000019, GO:0016021=PMID:15260953, GO:0005391=PMID:15260953} P13637 Sodium/potassium-transporting ATPase subunit alpha-3 protein 20130301 {GO:0008344=IEA, GO:0030424=IEA, GO:0005794=IDA, GO:0005886=TAS, GO:0005783=IDA, GO:0042493=IEA, GO:0015077=IEA, GO:0045202=ISS, GO:0005634=IEA, GO:0005890=IC, GO:0055085=TAS, GO:0005524=NAS, GO:0046872=IEA, GO:0019829=IEA, GO:0006754=IEA, GO:0035235=IEA, GO:0034220=TAS, GO:0000166=IEA, GO:0043209=IEA, GO:0008542=IEA, GO:0007613=IEA, GO:0016021=NAS, GO:0005391=IMP} ATP biosynthetic process, adult locomotory behavior, ion transmembrane transport, ionotropic glutamate receptor signaling pathway, memory, response to drug, transmembrane transport, visual learning Golgi apparatus, axon, endoplasmic reticulum, integral to membrane, myelin sheath, nucleus, plasma membrane, sodium:potassium-exchanging ATPase complex, synapse ATP binding, cation-transporting ATPase activity, metal ion binding, monovalent inorganic cation transmembrane transporter activity, nucleotide binding, sodium:potassium-exchanging ATPase activity Human ATP1A4 Reactome UniProtKB {GO:0005886=Reactome:REACT_25287, GO:0007283=GO_REF:0000019, GO:0030317=PMID:12112599, GO:0005890=PMID:7809153, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0019829=GO_REF:0000002, GO:0009566=GO_REF:0000019, GO:0006754=GO_REF:0000002, GO:0034220=Reactome:REACT_25300, GO:0005887=PMID:7809153, GO:0030641=PMID:12112599, GO:0042391=GO_REF:0000019, GO:0015991=PMID:7809153, GO:0016021=GO_REF:0000038, GO:0006814=PMID:7809153, GO:0006813=PMID:7809153, GO:0005391=PMID:7809153} Q13733 Sodium/potassium-transporting ATPase subunit alpha-4 protein 20130301 {GO:0005886=TAS, GO:0007283=IEA, GO:0030317=IDA, GO:0005890=TAS, GO:0055085=TAS, GO:0005524=IEA, GO:0046872=IEA, GO:0019829=IEA, GO:0009566=IEA, GO:0006754=IEA, GO:0034220=TAS, GO:0005887=NAS, GO:0030641=IDA, GO:0042391=IEA, GO:0015991=TAS, GO:0016021=IEA, GO:0006814=TAS, GO:0006813=TAS, GO:0005391=TAS} ATP biosynthetic process, ATP hydrolysis coupled proton transport, fertilization, ion transmembrane transport, potassium ion transport, regulation of cellular pH, regulation of membrane potential, sodium ion transport, sperm motility, spermatogenesis, transmembrane transport integral to membrane, integral to plasma membrane, plasma membrane, sodium:potassium-exchanging ATPase complex ATP binding, cation-transporting ATPase activity, metal ion binding, sodium:potassium-exchanging ATPase activity Human ATP1B1 BHF-UCL UniProtKB {GO:0005515=PMID:17947299, GO:0001666=GO_REF:0000019, GO:0005886=Reactome:REACT_25287, GO:0050900=Reactome:REACT_12051, GO:0005890=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0016323=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0034220=Reactome:REACT_25300, GO:0007596=Reactome:REACT_604, GO:0005901=GO_REF:0000019, GO:0006810=PMID:2559024, GO:0006814=GO_REF:0000002, GO:0007155=GO_REF:0000037, GO:0006813=GO_REF:0000002, GO:0005391=GO_REF:0000019} P05026 Sodium/potassium-transporting ATPase subunit beta-1 protein 20080507 {GO:0005515=IPI, GO:0001666=IEA, GO:0005886=TAS, GO:0050900=TAS, GO:0005890=IEA, GO:0055085=TAS, GO:0016323=IEA, GO:0016324=IEA, GO:0034220=TAS, GO:0007596=TAS, GO:0005901=IEA, GO:0006810=TAS, GO:0006814=IEA, GO:0007155=IEA, GO:0006813=IEA, GO:0005391=IEA} blood coagulation, cell adhesion, ion transmembrane transport, leukocyte migration, potassium ion transport, response to hypoxia, sodium ion transport, transmembrane transport, transport apical plasma membrane, basolateral plasma membrane, caveola, plasma membrane, sodium:potassium-exchanging ATPase complex protein binding, sodium:potassium-exchanging ATPase activity Human UniProtKB:O76024 ATP1B2 Reactome UniProtKB {GO:0005515=PMID:11027149, GO:0005886=Reactome:REACT_25287, GO:0005890=GO_REF:0000002, GO:0050900=Reactome:REACT_12051, GO:0055085=Reactome:REACT_15518, GO:0005737=GO_REF:0000019, GO:0034220=Reactome:REACT_25300, GO:0007596=Reactome:REACT_604, GO:0006810=PMID:2538450, GO:0006814=GO_REF:0000002, GO:0007155=GO_REF:0000037, GO:0006813=GO_REF:0000002, GO:0005391=PMID:2538450} P14415 Sodium/potassium-transporting ATPase subunit beta-2 protein 20130301 {GO:0005515=IPI, GO:0005886=TAS, GO:0005890=IEA, GO:0050900=TAS, GO:0055085=TAS, GO:0005737=IEA, GO:0034220=TAS, GO:0007596=TAS, GO:0006810=TAS, GO:0006814=IEA, GO:0007155=IEA, GO:0006813=IEA, GO:0005391=TAS} blood coagulation, cell adhesion, ion transmembrane transport, leukocyte migration, potassium ion transport, sodium ion transport, transmembrane transport, transport cytoplasm, plasma membrane, sodium:potassium-exchanging ATPase complex protein binding, sodium:potassium-exchanging ATPase activity Human ATP1B3 Reactome UniProtKB {GO:0042470=GO_REF:0000039, GO:0005886=Reactome:REACT_25287, GO:0005890=GO_REF:0000019, GO:0050900=Reactome:REACT_12051, GO:0055085=Reactome:REACT_15518, GO:0005737=GO_REF:0000019, GO:0034220=Reactome:REACT_25300, GO:0007596=Reactome:REACT_604, GO:0005901=GO_REF:0000019, GO:0006810=PMID:8798450, GO:0006814=GO_REF:0000002, GO:0006813=GO_REF:0000002, GO:0005391=GO_REF:0000019} P54709 Sodium/potassium-transporting ATPase subunit beta-3 protein 20130301 {GO:0042470=IEA, GO:0005886=TAS, GO:0005890=IEA, GO:0050900=TAS, GO:0055085=TAS, GO:0005737=IEA, GO:0034220=TAS, GO:0007596=TAS, GO:0005901=IEA, GO:0006810=TAS, GO:0006814=IEA, GO:0006813=IEA, GO:0005391=IEA} blood coagulation, ion transmembrane transport, leukocyte migration, potassium ion transport, sodium ion transport, transmembrane transport, transport caveola, cytoplasm, melanosome, plasma membrane, sodium:potassium-exchanging ATPase complex sodium:potassium-exchanging ATPase activity Human ATP2A1 BHF-UCL UniProtKB {GO:0005515=PMID:9295312, GO:0034976=PMID:19061639, GO:0046872=GO_REF:0000002, GO:0042803=PMID:11402072, GO:0034220=Reactome:REACT_25300, GO:0008637=PMID:19061639, GO:0000166=GO_REF:0000002, GO:0051561=PMID:19061639, GO:0006816=PMID:9405806, GO:0031095=Reactome:REACT_23784, GO:0090076=PMID:8841193, GO:0005509=PMID:9405806, GO:0033017=PMID:8040329, GO:0034704=PMID:11402072, GO:0005524=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0019829=GO_REF:0000002, GO:0005388=PMID:8729696, GO:0070509=PMID:8040329, GO:0016529=PMID:8841193, GO:0007596=Reactome:REACT_604, GO:0031448=PMID:12479237, GO:0070059=PMID:19061639, GO:0005789=Reactome:REACT_25316, GO:0051659=PMID:19061639, GO:0016021=PMID:9405806, GO:0032470=PMID:11402072, GO:0032471=PMID:11402072} O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 protein 20100524 {GO:0005515=IPI, GO:0034976=IMP, GO:0046872=IEA, GO:0042803=IPI, GO:0034220=TAS, GO:0008637=IMP, GO:0000166=IEA, GO:0051561=IMP, GO:0006816=IMP, GO:0031095=TAS, GO:0090076=IDA, GO:0005509=IMP, GO:0033017=IC, GO:0034704=IC, GO:0005524=IEA, GO:0055085=TAS, GO:0019829=IEA, GO:0005388=IDA, GO:0070509=IMP, GO:0016529=NAS, GO:0007596=TAS, GO:0031448=IDA, GO:0070059=IMP, GO:0005789=TAS, GO:0051659=IMP, GO:0016021=NAS, GO:0032470=IMP, GO:0032471=IMP} apoptotic mitochondrial changes, blood coagulation, calcium ion import, calcium ion transport, elevation of endoplasmic reticulum calcium ion concentration, elevation of mitochondrial calcium ion concentration, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, ion transmembrane transport, maintenance of mitochondrion location, positive regulation of fast-twitch skeletal muscle fiber contraction, reduction of endoplasmic reticulum calcium ion concentration, relaxation of skeletal muscle, response to endoplasmic reticulum stress, transmembrane transport calcium channel complex, endoplasmic reticulum membrane, integral to membrane, platelet dense tubular network membrane, sarcoplasmic reticulum, sarcoplasmic reticulum membrane ATP binding, calcium ion binding, calcium-transporting ATPase activity, cation-transporting ATPase activity, metal ion binding, nucleotide binding, protein binding, protein homodimerization activity Human ATP2A2 BHF-UCL UniProtKB {GO:0006984=GO_REF:0000019, GO:0070296=PMID:19095005, GO:0046872=GO_REF:0000037, GO:0043231=PMID:2844796, GO:0034220=Reactome:REACT_25300, GO:0000166=GO_REF:0000002, GO:0006810=PMID:2844796, GO:0007155=PMID:10080178, GO:0031095=Reactome:REACT_23784, GO:0045822=GO_REF:0000019, GO:0006874=GO_REF:0000019, GO:0033017=PMID:19095005, GO:0005524=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0019829=GO_REF:0000002, GO:0044548=PMID:12804600, GO:0005388=PMID:2844796, GO:0016529=PMID:12804600, GO:0008544=PMID:10080178, GO:0016020=PMID:2844796, GO:0002026=GO_REF:0000019, GO:0005887=PMID:2844796, GO:0007596=Reactome:REACT_604, GO:0086039=PMID:22679139, GO:0005789=Reactome:REACT_25316, GO:0055119=PMID:22679139, GO:0010460=PMID:22679139, GO:0016021=GO_REF:0000002, GO:0086036=PMID:22679139} P16615 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 protein 20130206 {GO:0006984=IEA, GO:0070296=TAS, GO:0046872=IEA, GO:0043231=TAS, GO:0034220=TAS, GO:0000166=IEA, GO:0006810=TAS, GO:0007155=TAS, GO:0031095=TAS, GO:0045822=IEA, GO:0006874=IEA, GO:0033017=TAS, GO:0005524=IEA, GO:0055085=TAS, GO:0019829=IEA, GO:0044548=IPI, GO:0005388=TAS, GO:0016529=IDA, GO:0008544=TAS, GO:0016020=TAS, GO:0002026=IEA, GO:0005887=TAS, GO:0007596=TAS, GO:0086039=TAS, GO:0005789=TAS, GO:0055119=TAS, GO:0010460=TAS, GO:0016021=IEA, GO:0086036=TAS} ER-nucleus signaling pathway, blood coagulation, cell adhesion, cellular calcium ion homeostasis, epidermis development, ion transmembrane transport, negative regulation of heart contraction, positive regulation of heart rate, regulation of cardiac muscle cell membrane potential, regulation of the force of heart contraction, relaxation of cardiac muscle, sarcoplasmic reticulum calcium ion transport, transmembrane transport, transport endoplasmic reticulum membrane, integral to membrane, integral to plasma membrane, intracellular membrane-bounded organelle, membrane, platelet dense tubular network membrane, sarcoplasmic reticulum, sarcoplasmic reticulum membrane ATP binding, S100 protein binding, calcium-transporting ATPase activity, calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential, cation-transporting ATPase activity, metal ion binding, nucleotide binding Human ATP2A3 Reactome UniProtKB {GO:0031965=GO_REF:0000039, GO:0005783=PMID:8809064, GO:0033017=GO_REF:0000039, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0019829=GO_REF:0000002, GO:0005388=GO_REF:0000003, GO:0034220=Reactome:REACT_25300, GO:0016529=PMID:8809064, GO:0007596=Reactome:REACT_604, GO:0006810=PMID:8809064, GO:0005789=Reactome:REACT_25316, GO:0006816=PMID:8809064, GO:0016021=GO_REF:0000037, GO:0031095=Reactome:REACT_23784} Q93084 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 protein 20130301 {GO:0031965=IEA, GO:0005783=IDA, GO:0033017=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0046872=IEA, GO:0019829=IEA, GO:0005388=IEA, GO:0034220=TAS, GO:0016529=IDA, GO:0007596=TAS, GO:0006810=TAS, GO:0005789=TAS, GO:0006816=TAS, GO:0016021=IEA, GO:0031095=TAS} blood coagulation, calcium ion transport, ion transmembrane transport, transmembrane transport, transport endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, nuclear membrane, platelet dense tubular network membrane, sarcoplasmic reticulum, sarcoplasmic reticulum membrane ATP binding, calcium-transporting ATPase activity, cation-transporting ATPase activity, metal ion binding Human ATP2B1 Reactome UniProtKB {GO:0019829=GO_REF:0000002, GO:0005516=GO_REF:0000037, GO:0005388=GO_REF:0000003, GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_23956, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:8396145, GO:0006810=PMID:8396145, GO:0016021=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037} P20020 Plasma membrane calcium-transporting ATPase 1 protein 20130301 {GO:0019829=IEA, GO:0005516=IEA, GO:0005388=IEA, GO:0034220=TAS, GO:0005886=TAS, GO:0007596=TAS, GO:0005887=TAS, GO:0006810=TAS, GO:0016021=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0046872=IEA} blood coagulation, ion transmembrane transport, transmembrane transport, transport integral to membrane, integral to plasma membrane, plasma membrane ATP binding, calcium-transporting ATPase activity, calmodulin binding, cation-transporting ATPase activity, metal ion binding Human ATP2B2 Reactome UniProtKB {GO:0008361=GO_REF:0000019, GO:0005516=GO_REF:0000037, GO:0005886=Reactome:REACT_23956, GO:0005783=GO_REF:0000019, GO:0051928=GO_REF:0000019, GO:0007605=PMID:15829536, GO:0060088=GO_REF:0000019, GO:0046068=GO_REF:0000019, GO:0030899=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0021707=GO_REF:0000019, GO:0040011=GO_REF:0000019, GO:0005737=PMID:15765049, GO:0016324=GO_REF:0000019, GO:0034220=Reactome:REACT_25300, GO:0021702=GO_REF:0000019, GO:0048167=GO_REF:0000019, GO:0030182=PMID:11259493, GO:0006810=PMID:1313367, GO:0090102=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0050885=GO_REF:0000019, GO:0006816=PMID:17234811, GO:0007626=GO_REF:0000019, GO:0045299=GO_REF:0000019, GO:0006996=GO_REF:0000019, GO:0051480=PMID:17234811, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0042428=GO_REF:0000019, GO:0005929=GO_REF:0000019, GO:0005388=PMID:1313367, GO:0007595=GO_REF:0000019, GO:0050808=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0050910=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q01814 Plasma membrane calcium-transporting ATPase 2 protein 20130301 {GO:0008361=IEA, GO:0005516=IEA, GO:0005886=TAS, GO:0005783=IEA, GO:0051928=IEA, GO:0007605=IMP, GO:0060088=IEA, GO:0046068=IEA, GO:0030899=IEA, GO:0046872=IEA, GO:0021707=IEA, GO:0040011=IEA, GO:0005737=IDA, GO:0016324=IEA, GO:0034220=TAS, GO:0021702=IEA, GO:0048167=IEA, GO:0030182=IDA, GO:0006810=NAS, GO:0090102=IEA, GO:0043025=IEA, GO:0050885=IEA, GO:0006816=IMP, GO:0007626=IEA, GO:0045299=IEA, GO:0006996=IEA, GO:0051480=IMP, GO:0055085=TAS, GO:0005524=IEA, GO:0042428=IEA, GO:0005929=IEA, GO:0005388=NAS, GO:0007595=IEA, GO:0050808=IEA, GO:0007596=TAS, GO:0050910=IEA, GO:0016021=IEA} auditory receptor cell stereocilium organization, blood coagulation, cGMP metabolic process, calcium ion transport, cerebellar Purkinje cell differentiation, cerebellar granule cell differentiation, cochlea development, cytosolic calcium ion homeostasis, detection of mechanical stimulus involved in sensory perception of sound, ion transmembrane transport, lactation, locomotion, locomotory behavior, neuromuscular process controlling balance, neuron differentiation, organelle organization, otolith mineralization, positive regulation of calcium ion transport, regulation of cell size, regulation of synaptic plasticity, sensory perception of sound, serotonin metabolic process, synapse organization, transmembrane transport, transport apical plasma membrane, cilium, cytoplasm, endoplasmic reticulum, integral to membrane, neuronal cell body, plasma membrane ATP binding, calcium-dependent ATPase activity, calcium-transporting ATPase activity, calmodulin binding, metal ion binding Human ATP2B3 Reactome UniProtKB {GO:0005388=GO_REF:0000003, GO:0005516=GO_REF:0000037, GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_23956, GO:0007596=Reactome:REACT_604, GO:0006810=PMID:8765088, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q16720 Plasma membrane calcium-transporting ATPase 3 protein 20130301 {GO:0005388=IEA, GO:0005516=IEA, GO:0034220=TAS, GO:0005886=TAS, GO:0007596=TAS, GO:0006810=TAS, GO:0016021=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0046872=IEA} blood coagulation, ion transmembrane transport, transmembrane transport, transport integral to membrane, plasma membrane ATP binding, calcium-transporting ATPase activity, calmodulin binding, metal ion binding Human ATP2B4 Reactome UniProtKB {GO:0005516=GO_REF:0000037, GO:0005388=GO_REF:0000003, GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_23956, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:2137451, GO:0006810=PMID:2137451, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037} P23634 Plasma membrane calcium-transporting ATPase 4 protein 20130301 {GO:0005516=IEA, GO:0005388=IEA, GO:0034220=TAS, GO:0005886=TAS, GO:0007596=TAS, GO:0005887=TAS, GO:0006810=TAS, GO:0055085=TAS, GO:0005524=IEA, GO:0046872=IEA} blood coagulation, ion transmembrane transport, transmembrane transport, transport integral to plasma membrane, plasma membrane ATP binding, calcium-transporting ATPase activity, calmodulin binding, metal ion binding Human ATP2C1 GOC UniProtKB {GO:0005802=PMID:14632183, GO:0005794=PMID:11741891, GO:0031532=PMID:14632182, GO:0032468=PMID:14632183, GO:0006874=PMID:12810057, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0019829=GO_REF:0000002, GO:0016339=PMID:14632182, GO:0007165=PMID:12761501, GO:0005388=PMID:12810057, GO:0034220=Reactome:REACT_25300, GO:0000139=Reactome:REACT_25301, GO:0008544=PMID:10615129, GO:0006816=PMID:12810057, GO:0016021=PMID:10615129, GO:0004871=PMID:12761501, GO:0043123=PMID:12761501, GO:0032472=PMID:14632183} P98194 Calcium-transporting ATPase type 2C member 1 protein 20130413 {GO:0005802=IDA, GO:0005794=IDA, GO:0031532=IMP, GO:0032468=IMP, GO:0006874=IDA, GO:0055085=TAS, GO:0005524=IEA, GO:0046872=IEA, GO:0019829=IEA, GO:0016339=IMP, GO:0007165=IMP, GO:0005388=IDA, GO:0034220=TAS, GO:0000139=TAS, GO:0008544=IMP, GO:0006816=IDA, GO:0016021=NAS, GO:0004871=IMP, GO:0043123=IMP, GO:0032472=IMP} Golgi calcium ion homeostasis, Golgi calcium ion transport, actin cytoskeleton reorganization, calcium ion transport, calcium-dependent cell-cell adhesion, cellular calcium ion homeostasis, epidermis development, ion transmembrane transport, positive regulation of I-kappaB kinase/NF-kappaB cascade, signal transduction, transmembrane transport Golgi apparatus, Golgi membrane, integral to membrane, trans-Golgi network ATP binding, calcium-transporting ATPase activity, cation-transporting ATPase activity, metal ion binding, signal transducer activity Human ATP2C2 Reactome UniProtKB {GO:0019829=GO_REF:0000002, GO:0005388=GO_REF:0000003, GO:0034220=Reactome:REACT_25300, GO:0000139=Reactome:REACT_25301, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037} O75185 Calcium-transporting ATPase type 2C member 2 protein 20130301 {GO:0019829=IEA, GO:0005388=IEA, GO:0034220=TAS, GO:0000139=TAS, GO:0016021=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0046872=IEA} ion transmembrane transport, transmembrane transport Golgi membrane, integral to membrane ATP binding, calcium-transporting ATPase activity, cation-transporting ATPase activity, metal ion binding Human ATP4A Reactome UniProtKB {GO:0000287=GO_REF:0000002, GO:0005886=Reactome:REACT_25173, GO:0046982=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0045851=GO_REF:0000019, GO:0008900=GO_REF:0000003, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0019829=GO_REF:0000002, GO:0006754=GO_REF:0000002, GO:0034220=Reactome:REACT_25300, GO:0005887=PMID:2160952, GO:0015991=GO_REF:0000002, GO:0006810=PMID:2160952, GO:0010155=GO_REF:0000019, GO:0016021=GO_REF:0000002} P20648 Potassium-transporting ATPase alpha chain 1 protein 20130301 {GO:0000287=IEA, GO:0005886=TAS, GO:0046982=IEA, GO:0042493=IEA, GO:0045851=IEA, GO:0008900=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0019829=IEA, GO:0006754=IEA, GO:0034220=TAS, GO:0005887=TAS, GO:0015991=IEA, GO:0006810=TAS, GO:0010155=IEA, GO:0016021=IEA} ATP biosynthetic process, ATP hydrolysis coupled proton transport, ion transmembrane transport, pH reduction, regulation of proton transport, response to drug, transmembrane transport, transport integral to membrane, integral to plasma membrane, plasma membrane ATP binding, cation-transporting ATPase activity, hydrogen:potassium-exchanging ATPase activity, magnesium ion binding, protein heterodimerization activity Human ATP4B Reactome UniProtKB {GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_25173, GO:0032496=GO_REF:0000019, GO:0010243=GO_REF:0000019, GO:0008900=PMID:1656976, GO:0007155=GO_REF:0000037, GO:0006814=GO_REF:0000002, GO:0005890=GO_REF:0000002, GO:0055085=Reactome:REACT_15518} P51164 Potassium-transporting ATPase subunit beta protein 20121219 {GO:0034220=TAS, GO:0005886=TAS, GO:0032496=IEA, GO:0010243=IEA, GO:0008900=TAS, GO:0007155=IEA, GO:0006814=IEA, GO:0005890=IEA, GO:0055085=TAS} cell adhesion, ion transmembrane transport, response to lipopolysaccharide, response to organic nitrogen, sodium ion transport, transmembrane transport plasma membrane, sodium:potassium-exchanging ATPase complex hydrogen:potassium-exchanging ATPase activity Human ATP5A1 GOC UniProtKB {GO:0006629=GO_REF:0000024, GO:0005515=PMID:22309213, GO:0043499=PMID:10077593, GO:0042288=PMID:17643490, GO:0006200=PMID:12110673, GO:0005886=PMID:10077593, GO:0005743=PMID:19016746, GO:0044281=Reactome:REACT_111217, GO:0009790=GO_REF:0000024, GO:0005739=PMID:1830491, GO:0006754=PMID:1830491, GO:0008180=PMID:18850735, GO:0046961=GO_REF:0000002, GO:0005759=Reactome:REACT_1985, GO:0016887=PMID:12110673, GO:0015986=GO_REF:0000002, GO:0046034=GO_REF:0000002, GO:0022857=PMID:12110673, GO:0005524=GO_REF:0000024, GO:0005753=PMID:12110673, GO:0022904=Reactome:REACT_6305, GO:0001937=PMID:10077593, GO:0046933=GO_REF:0000024, GO:0042776=Reactome:REACT_6759, GO:0045261=GO_REF:0000037, GO:0015991=GO_REF:0000002, GO:0015992=GO_REF:0000002} P25705 ATP synthase subunit alpha, mitochondrial protein 20130413 {GO:0006629=ISS, GO:0005515=IPI, GO:0043499=IDA, GO:0042288=IDA, GO:0006200=IDA, GO:0005886=IDA, GO:0005743=IDA, GO:0044281=TAS, GO:0009790=ISS, GO:0005739=NAS, GO:0006754=NAS, GO:0008180=IDA, GO:0046961=IEA, GO:0005759=TAS, GO:0016887=IDA, GO:0015986=IEA, GO:0046034=IEA, GO:0022857=IC, GO:0005524=ISS, GO:0005753=IDA, GO:0022904=TAS, GO:0001937=IMP, GO:0046933=ISS, GO:0042776=TAS, GO:0045261=IEA, GO:0015991=IEA, GO:0015992=IEA} ATP biosynthetic process, ATP catabolic process, ATP hydrolysis coupled proton transport, ATP metabolic process, ATP synthesis coupled proton transport, embryo development, lipid metabolic process, mitochondrial ATP synthesis coupled proton transport, negative regulation of endothelial cell proliferation, proton transport, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial matrix, mitochondrial proton-transporting ATP synthase complex, mitochondrion, plasma membrane, proton-transporting ATP synthase complex, catalytic core F(1), signalosome ATP binding, ATPase activity, MHC class I protein binding, eukaryotic cell surface binding, protein binding, proton-transporting ATP synthase activity, rotational mechanism, proton-transporting ATPase activity, rotational mechanism, transmembrane transporter activity Human ATP5B GOC UniProtKB {GO:0042645=PMID:18063578, GO:0005515=PMID:10077593, GO:0006629=GO_REF:0000019, GO:0005215=PMID:2870059, GO:0043499=PMID:10077593, GO:0042288=PMID:17643490, GO:0006200=PMID:12110673, GO:0005886=PMID:10077593, GO:0044281=Reactome:REACT_111217, GO:0006091=PMID:2870059, GO:0005739=GO_REF:0000052, GO:0006754=PMID:17510399, GO:0046961=PMID:17510399, GO:0005759=Reactome:REACT_1985, GO:0006933=GO_REF:0000019, GO:0016887=PMID:12110673, GO:0031966=PMID:8006588, GO:0015986=GO_REF:0000002, GO:0009986=PMID:17510399, GO:0022857=PMID:12110673, GO:0001525=PMID:17510399, GO:0005524=GO_REF:0000037, GO:0005754=PMID:2870059, GO:0005753=PMID:12110673, GO:0022904=Reactome:REACT_6305, GO:0046933=GO_REF:0000002, GO:0042776=Reactome:REACT_6759, GO:0045261=GO_REF:0000002, GO:0015991=GO_REF:0000002, GO:0051453=PMID:17510399, GO:0015992=PMID:17510399} P06576 ATP synthase subunit beta, mitochondrial protein 20130413 {GO:0042645=IDA, GO:0005515=IPI, GO:0006629=IEA, GO:0005215=NAS, GO:0043499=IDA, GO:0042288=IDA, GO:0006200=IDA, GO:0005886=IDA, GO:0044281=TAS, GO:0006091=NAS, GO:0005739=IDA, GO:0006754=IMP, GO:0046961=IMP, GO:0005759=TAS, GO:0006933=IEA, GO:0016887=IDA, GO:0031966=IDA, GO:0015986=IEA, GO:0009986=IDA, GO:0022857=IC, GO:0001525=IMP, GO:0005524=IEA, GO:0005754=NAS, GO:0005753=IDA, GO:0022904=TAS, GO:0046933=IEA, GO:0042776=TAS, GO:0045261=IEA, GO:0015991=IEA, GO:0051453=IMP, GO:0015992=IMP} ATP biosynthetic process, ATP catabolic process, ATP hydrolysis coupled proton transport, ATP synthesis coupled proton transport, angiogenesis, generation of precursor metabolites and energy, lipid metabolic process, mitochondrial ATP synthesis coupled proton transport, negative regulation of cell adhesion involved in substrate-bound cell migration, proton transport, regulation of intracellular pH, respiratory electron transport chain, small molecule metabolic process cell surface, mitochondrial matrix, mitochondrial membrane, mitochondrial nucleoid, mitochondrial proton-transporting ATP synthase complex, mitochondrial proton-transporting ATP synthase, catalytic core, mitochondrion, plasma membrane, proton-transporting ATP synthase complex, catalytic core F(1) ATP binding, ATPase activity, MHC class I protein binding, eukaryotic cell surface binding, protein binding, proton-transporting ATP synthase activity, rotational mechanism, proton-transporting ATPase activity, rotational mechanism, transmembrane transporter activity, transporter activity Human ATP5C1 GOC UniProtKB {GO:0015986=GO_REF:0000002, GO:0006200=PMID:8227057, GO:0022857=PMID:12110673, GO:0005743=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0006119=PMID:8227057, GO:0005753=PMID:12110673, GO:0022904=Reactome:REACT_6305, GO:0005739=PMID:12887009, GO:0006754=PMID:8227057, GO:0046961=GO_REF:0000002, GO:0042776=Reactome:REACT_6759, GO:0005759=Reactome:REACT_1985, GO:0046933=GO_REF:0000002, GO:0045261=GO_REF:0000038, GO:0000275=PMID:8227057, GO:0016887=PMID:12110673} P36542 ATP synthase subunit gamma, mitochondrial protein 20130413 {GO:0015986=IEA, GO:0006200=NAS, GO:0022857=IC, GO:0005743=ISS, GO:0044281=TAS, GO:0006119=NAS, GO:0005753=IDA, GO:0022904=TAS, GO:0005739=NAS, GO:0006754=NAS, GO:0046961=IEA, GO:0042776=TAS, GO:0005759=TAS, GO:0046933=IEA, GO:0045261=IEA, GO:0000275=NAS, GO:0016887=IDA} ATP biosynthetic process, ATP catabolic process, ATP synthesis coupled proton transport, mitochondrial ATP synthesis coupled proton transport, oxidative phosphorylation, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial matrix, mitochondrial proton-transporting ATP synthase complex, mitochondrial proton-transporting ATP synthase complex, catalytic core F(1), mitochondrion, proton-transporting ATP synthase complex, catalytic core F(1) ATPase activity, proton-transporting ATP synthase activity, rotational mechanism, proton-transporting ATPase activity, rotational mechanism, transmembrane transporter activity Human ATP5D Reactome UniProtKB {GO:0005215=PMID:1531933, GO:0006200=PMID:12539966, GO:0022857=PMID:12110673, GO:0005743=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0005524=PMID:12539966, GO:0005753=PMID:12110673, GO:0006119=PMID:12539966, GO:0022904=Reactome:REACT_6305, GO:0005739=PMID:12887009, GO:0006754=PMID:12539966, GO:0043531=PMID:12539966, GO:0046961=GO_REF:0000002, GO:0005759=Reactome:REACT_1985, GO:0046933=GO_REF:0000002, GO:0042776=Reactome:REACT_6759, GO:0000275=PMID:12539966, GO:0046688=PMID:12539966, GO:0016887=PMID:12110673} P30049 ATP synthase subunit delta, mitochondrial protein 20050630 {GO:0005215=NAS, GO:0006200=NAS, GO:0022857=IC, GO:0005743=ISS, GO:0044281=TAS, GO:0005524=NAS, GO:0005753=IDA, GO:0006119=NAS, GO:0022904=TAS, GO:0005739=NAS, GO:0006754=NAS, GO:0043531=NAS, GO:0046961=IEA, GO:0005759=TAS, GO:0046933=IEA, GO:0042776=TAS, GO:0000275=NAS, GO:0046688=NAS, GO:0016887=IDA} ATP biosynthetic process, ATP catabolic process, mitochondrial ATP synthesis coupled proton transport, oxidative phosphorylation, respiratory electron transport chain, response to copper ion, small molecule metabolic process mitochondrial inner membrane, mitochondrial matrix, mitochondrial proton-transporting ATP synthase complex, mitochondrial proton-transporting ATP synthase complex, catalytic core F(1), mitochondrion ADP binding, ATP binding, ATPase activity, proton-transporting ATP synthase activity, rotational mechanism, proton-transporting ATPase activity, rotational mechanism, transmembrane transporter activity, transporter activity Human ATP5E GOC UniProtKB {GO:0022904=Reactome:REACT_6305, GO:0006200=PMID:12110673, GO:0046961=GO_REF:0000002, GO:0005759=Reactome:REACT_1985, GO:0042776=Reactome:REACT_6759, GO:0046933=GO_REF:0000002, GO:0022857=PMID:12110673, GO:0044281=Reactome:REACT_111217, GO:0000275=GO_REF:0000002, GO:0016887=PMID:12110673, GO:0005753=PMID:12110673} P56381 ATP synthase subunit epsilon, mitochondrial protein 20130413 {GO:0022904=TAS, GO:0006200=IDA, GO:0046961=IEA, GO:0005759=TAS, GO:0042776=TAS, GO:0046933=IEA, GO:0022857=IC, GO:0044281=TAS, GO:0000275=IEA, GO:0016887=IDA, GO:0005753=IDA} ATP catabolic process, mitochondrial ATP synthesis coupled proton transport, respiratory electron transport chain, small molecule metabolic process mitochondrial matrix, mitochondrial proton-transporting ATP synthase complex, mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) ATPase activity, proton-transporting ATP synthase activity, rotational mechanism, proton-transporting ATPase activity, rotational mechanism, transmembrane transporter activity Human ATP5F1 InterPro UniProtKB {GO:0005515=PMID:19016746, GO:0015986=GO_REF:0000002, GO:0006200=PMID:12110673, GO:0015078=GO_REF:0000002, GO:0022857=PMID:12110673, GO:0005743=Reactome:REACT_1985, GO:0044281=Reactome:REACT_111217, GO:0005753=PMID:12110673, GO:0022904=Reactome:REACT_6305, GO:0046933=GO_REF:0000033, GO:0005759=PMID:1831354, GO:0042776=Reactome:REACT_6759, GO:0000276=GO_REF:0000002, GO:0016887=PMID:12110673} Q5QNZ2 ATP synthase subunit b, mitochondrial protein 20130413 {GO:0005515=IPI, GO:0015986=IEA, GO:0006200=IDA, GO:0015078=IEA, GO:0022857=IC, GO:0005743=TAS, GO:0044281=TAS, GO:0005753=IDA, GO:0022904=TAS, GO:0046933=IBA, GO:0005759=NAS, GO:0042776=TAS, GO:0000276=IEA, GO:0016887=IDA} ATP catabolic process, ATP synthesis coupled proton transport, mitochondrial ATP synthesis coupled proton transport, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial matrix, mitochondrial proton-transporting ATP synthase complex, mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ATPase activity, hydrogen ion transmembrane transporter activity, protein binding, proton-transporting ATP synthase activity, rotational mechanism, transmembrane transporter activity Human InterPro:IPR008688|InterPro:IPR013837 ATP5G1 LIFEdb UniProtKB {GO:0005215=PMID:8328972, GO:0015986=GO_REF:0000002, GO:0015078=GO_REF:0000002, GO:0005743=Reactome:REACT_1985, GO:0044281=Reactome:REACT_111217, GO:0008289=GO_REF:0000037, GO:0005753=GO_REF:0000024, GO:0022904=Reactome:REACT_6305, GO:0005739=GO_REF:0000054, GO:0042776=Reactome:REACT_6759, GO:0015991=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0045263=GO_REF:0000037} P05496 ATP synthase lipid-binding protein, mitochondrial protein 20100607 {GO:0005215=NAS, GO:0015986=IEA, GO:0015078=IEA, GO:0005743=TAS, GO:0044281=TAS, GO:0008289=IEA, GO:0005753=ISS, GO:0022904=TAS, GO:0005739=IDA, GO:0042776=TAS, GO:0015991=IEA, GO:0016021=IEA, GO:0045263=IEA} ATP hydrolysis coupled proton transport, ATP synthesis coupled proton transport, mitochondrial ATP synthesis coupled proton transport, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane, mitochondrial proton-transporting ATP synthase complex, mitochondrion, proton-transporting ATP synthase complex, coupling factor F(o) hydrogen ion transmembrane transporter activity, lipid binding, transporter activity Human ATP5G2 PINC UniProtKB {GO:0005215=PMID:8328972, GO:0015986=GO_REF:0000002, GO:0045471=GO_REF:0000019, GO:0015078=GO_REF:0000002, GO:0015991=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0045263=GO_REF:0000037, GO:0005753=PMID:8328972, GO:0008289=GO_REF:0000037} Q06055 ATP synthase lipid-binding protein, mitochondrial protein 20040811 {GO:0005215=NAS, GO:0015986=IEA, GO:0045471=IEA, GO:0015078=IEA, GO:0015991=IEA, GO:0016021=IEA, GO:0045263=IEA, GO:0005753=TAS, GO:0008289=IEA} ATP hydrolysis coupled proton transport, ATP synthesis coupled proton transport, response to ethanol integral to membrane, mitochondrial proton-transporting ATP synthase complex, proton-transporting ATP synthase complex, coupling factor F(o) hydrogen ion transmembrane transporter activity, lipid binding, transporter activity Human ATP5G3 PINC UniProtKB {GO:0005215=PMID:7698763, GO:0015986=GO_REF:0000002, GO:0015078=GO_REF:0000002, GO:0015991=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0045263=GO_REF:0000037, GO:0005753=PMID:7698763, GO:0008289=GO_REF:0000037} P48201 ATP synthase lipid-binding protein, mitochondrial protein 20030904 {GO:0005215=NAS, GO:0015986=IEA, GO:0015078=IEA, GO:0015991=IEA, GO:0016021=IEA, GO:0045263=IEA, GO:0005753=TAS, GO:0008289=IEA} ATP hydrolysis coupled proton transport, ATP synthesis coupled proton transport integral to membrane, mitochondrial proton-transporting ATP synthase complex, proton-transporting ATP synthase complex, coupling factor F(o) hydrogen ion transmembrane transporter activity, lipid binding, transporter activity Human ATP5H GOC UniProtKB {GO:0022904=Reactome:REACT_6305, GO:0015986=GO_REF:0000002, GO:0006200=PMID:12110673, GO:0042776=Reactome:REACT_6759, GO:0015078=GO_REF:0000002, GO:0022857=PMID:12110673, GO:0005743=Reactome:REACT_1985, GO:0000276=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0016887=PMID:12110673, GO:0005753=PMID:12110673} O75947 ATP synthase subunit d, mitochondrial protein 20130413 {GO:0022904=TAS, GO:0015986=IEA, GO:0006200=IDA, GO:0042776=TAS, GO:0015078=IEA, GO:0022857=IC, GO:0005743=TAS, GO:0000276=IEA, GO:0044281=TAS, GO:0016887=IDA, GO:0005753=IDA} ATP catabolic process, ATP synthesis coupled proton transport, mitochondrial ATP synthesis coupled proton transport, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial proton-transporting ATP synthase complex, mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ATPase activity, hydrogen ion transmembrane transporter activity, transmembrane transporter activity Human ATP5I GOC UniProtKB {GO:0005739=GO_REF:0000052, GO:0022904=Reactome:REACT_6305, GO:0006200=PMID:12110673, GO:0042776=Reactome:REACT_6759, GO:0015078=GO_REF:0000002, GO:0022857=PMID:12110673, GO:0005743=Reactome:REACT_1985, GO:0000276=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0016887=PMID:12110673, GO:0005753=PMID:12110673} P56385 ATP synthase subunit e, mitochondrial protein 20130413 {GO:0005739=IDA, GO:0022904=TAS, GO:0006200=IDA, GO:0042776=TAS, GO:0015078=IEA, GO:0022857=IC, GO:0005743=TAS, GO:0000276=IEA, GO:0044281=TAS, GO:0016887=IDA, GO:0005753=IDA} ATP catabolic process, mitochondrial ATP synthesis coupled proton transport, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial proton-transporting ATP synthase complex, mitochondrial proton-transporting ATP synthase complex, coupling factor F(o), mitochondrion ATPase activity, hydrogen ion transmembrane transporter activity, transmembrane transporter activity Human ATP5J GOC UniProtKB {GO:0005215=PMID:1830479, GO:0015986=GO_REF:0000002, GO:0006200=PMID:12110673, GO:0015078=GO_REF:0000002, GO:0022857=PMID:12110673, GO:0005743=Reactome:REACT_1985, GO:0044281=Reactome:REACT_111217, GO:0005753=PMID:12110673, GO:0005739=GO_REF:0000052, GO:0022904=Reactome:REACT_6305, GO:0042776=Reactome:REACT_6759, GO:0000276=GO_REF:0000002, GO:0016887=PMID:12110673} P18859 ATP synthase-coupling factor 6, mitochondrial protein 20130413 {GO:0005215=NAS, GO:0015986=IEA, GO:0006200=IDA, GO:0015078=IEA, GO:0022857=IC, GO:0005743=TAS, GO:0044281=TAS, GO:0005753=IDA, GO:0005739=IDA, GO:0022904=TAS, GO:0042776=TAS, GO:0000276=IEA, GO:0016887=IDA} ATP catabolic process, ATP synthesis coupled proton transport, mitochondrial ATP synthesis coupled proton transport, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial proton-transporting ATP synthase complex, mitochondrial proton-transporting ATP synthase complex, coupling factor F(o), mitochondrion ATPase activity, hydrogen ion transmembrane transporter activity, transmembrane transporter activity, transporter activity Human ATP5J2 GOC UniProtKB {GO:0022904=Reactome:REACT_6305, GO:0006200=PMID:12110673, GO:0042776=Reactome:REACT_6759, GO:0022857=PMID:12110673, GO:0005743=Reactome:REACT_1985, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0016887=PMID:12110673, GO:0045263=GO_REF:0000037, GO:0015992=PMID:11959398, GO:0005753=PMID:12110673} P56134 ATP synthase subunit f, mitochondrial protein 20130413 {GO:0022904=TAS, GO:0006200=IDA, GO:0042776=TAS, GO:0022857=IC, GO:0005743=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0016887=IDA, GO:0045263=IEA, GO:0015992=NAS, GO:0005753=IDA} ATP catabolic process, mitochondrial ATP synthesis coupled proton transport, proton transport, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane, mitochondrial proton-transporting ATP synthase complex, proton-transporting ATP synthase complex, coupling factor F(o) ATPase activity, transmembrane transporter activity Human ATP5L GOC UniProtKB {GO:0005739=GO_REF:0000054, GO:0022904=Reactome:REACT_6305, GO:0015986=GO_REF:0000002, GO:0006200=PMID:12110673, GO:0042776=Reactome:REACT_6759, GO:0015078=GO_REF:0000002, GO:0022857=PMID:12110673, GO:0005743=Reactome:REACT_1985, GO:0000276=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0016887=PMID:12110673, GO:0005753=PMID:12110673} O75964 ATP synthase subunit g, mitochondrial protein 20130413 {GO:0005739=IDA, GO:0022904=TAS, GO:0015986=IEA, GO:0006200=IDA, GO:0042776=TAS, GO:0015078=IEA, GO:0022857=IC, GO:0005743=TAS, GO:0000276=IEA, GO:0044281=TAS, GO:0016887=IDA, GO:0005753=IDA} ATP catabolic process, ATP synthesis coupled proton transport, mitochondrial ATP synthesis coupled proton transport, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial proton-transporting ATP synthase complex, mitochondrial proton-transporting ATP synthase complex, coupling factor F(o), mitochondrion ATPase activity, hydrogen ion transmembrane transporter activity, transmembrane transporter activity Human ATP5O Reactome UniProtKB {GO:0005215=PMID:7490082, GO:0015986=GO_REF:0000002, GO:0005886=PMID:17851741, GO:0006200=PMID:12110673, GO:0022857=PMID:12110673, GO:0005743=Reactome:REACT_1985, GO:0044281=Reactome:REACT_111217, GO:0032403=GO_REF:0000019, GO:0005753=PMID:7490082, GO:0022904=Reactome:REACT_6305, GO:0005739=PMID:17851741, GO:0006754=PMID:17851741, GO:0008144=PMID:15850986, GO:0046933=GO_REF:0000002, GO:0042776=Reactome:REACT_6759, GO:0000276=GO_REF:0000019, GO:0005496=GO_REF:0000019, GO:0016887=PMID:12110673, GO:0015992=PMID:17851741} P48047 ATP synthase subunit O, mitochondrial protein 20050526 {GO:0005215=NAS, GO:0015986=IEA, GO:0005886=IDA, GO:0006200=IDA, GO:0022857=IC, GO:0005743=TAS, GO:0044281=TAS, GO:0032403=IEA, GO:0005753=NAS, GO:0022904=TAS, GO:0005739=IDA, GO:0006754=NAS, GO:0008144=IDA, GO:0046933=IEA, GO:0042776=TAS, GO:0000276=IEA, GO:0005496=IEA, GO:0016887=IDA, GO:0015992=NAS} ATP biosynthetic process, ATP catabolic process, ATP synthesis coupled proton transport, mitochondrial ATP synthesis coupled proton transport, proton transport, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial proton-transporting ATP synthase complex, mitochondrial proton-transporting ATP synthase complex, coupling factor F(o), mitochondrion, plasma membrane ATPase activity, drug binding, protein complex binding, proton-transporting ATP synthase activity, rotational mechanism, steroid binding, transmembrane transporter activity, transporter activity Human ATP5S UniProtKB UniProtKB {GO:0006754=GO_REF:0000037, GO:0015078=PMID:6143319, GO:0005743=GO_REF:0000039, GO:0046872=GO_REF:0000037, GO:0045263=GO_REF:0000037, GO:0015992=PMID:6143319} Q99766 ATP synthase subunit s, mitochondrial protein 20021112 {GO:0006754=IEA, GO:0015078=NAS, GO:0005743=IEA, GO:0046872=IEA, GO:0045263=IEA, GO:0015992=NAS} ATP biosynthetic process, proton transport mitochondrial inner membrane, proton-transporting ATP synthase complex, coupling factor F(o) hydrogen ion transmembrane transporter activity, metal ion binding Human ATP6AP1 PINC UniProtKB {GO:0005215=PMID:8733135, GO:0005774=GO_REF:0000039, GO:0046961=GO_REF:0000002, GO:0046933=GO_REF:0000002, GO:0016469=PMID:8733135, GO:0015991=GO_REF:0000002, GO:0033180=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0015992=PMID:8733135} Q15904 V-type proton ATPase subunit S1 protein 20030904 {GO:0005215=TAS, GO:0005774=IEA, GO:0046961=IEA, GO:0046933=IEA, GO:0016469=TAS, GO:0015991=IEA, GO:0033180=IEA, GO:0016021=IEA, GO:0005524=IEA, GO:0015992=TAS} ATP hydrolysis coupled proton transport, proton transport integral to membrane, proton-transporting V-type ATPase, V1 domain, proton-transporting two-sector ATPase complex, vacuolar membrane ATP binding, proton-transporting ATP synthase activity, rotational mechanism, proton-transporting ATPase activity, rotational mechanism, transporter activity Human ATP6AP2 HGNC UniProtKB {GO:0005515=PMID:12045255, GO:0043005=GO_REF:0000019, GO:0002003=PMID:15746149, GO:0005886=Reactome:REACT_147891, GO:0044297=GO_REF:0000019, GO:0032914=PMID:16374430, GO:0043408=PMID:15746149, GO:0004872=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0004190=Reactome:REACT_147891, GO:0019899=GO_REF:0000019, GO:0044267=Reactome:REACT_17015, GO:0009897=PMID:15746149} O75787 Renin receptor protein 20070129 {GO:0005515=IPI, GO:0043005=IEA, GO:0002003=IDA, GO:0005886=TAS, GO:0044297=IEA, GO:0032914=IDA, GO:0043408=IDA, GO:0004872=IEA, GO:0016021=IEA, GO:0004190=EXP, GO:0019899=IEA, GO:0044267=TAS, GO:0009897=IDA} angiotensin maturation, cellular protein metabolic process, positive regulation of transforming growth factor beta1 production, regulation of MAPK cascade cell body, external side of plasma membrane, integral to membrane, neuron projection, plasma membrane aspartic-type endopeptidase activity, enzyme binding, protein binding, receptor activity Human ATP6V0A1 HPA UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005515=PMID:12649290, GO:0042470=GO_REF:0000039, GO:0005794=GO_REF:0000052, GO:0051701=Reactome:REACT_121237, GO:0005886=PMID:17360703, GO:0015078=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0055085=Reactome:REACT_15518, GO:0043231=GO_REF:0000052, GO:0006879=Reactome:REACT_25060, GO:0000220=GO_REF:0000002, GO:0033572=Reactome:REACT_25283, GO:0005737=GO_REF:0000052, GO:0030670=Reactome:REACT_121163, GO:0015991=GO_REF:0000002, GO:0051117=PMID:17360703, GO:0016021=GO_REF:0000037, GO:0090382=Reactome:REACT_121256, GO:0010008=Reactome:REACT_25268, GO:0033179=GO_REF:0000002} Q93050 V-type proton ATPase 116 kDa subunit a isoform 1 protein 20101115 {GO:0008286=TAS, GO:0005515=IPI, GO:0042470=IEA, GO:0005794=IDA, GO:0051701=TAS, GO:0005886=IDA, GO:0015078=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0055085=TAS, GO:0043231=IDA, GO:0006879=TAS, GO:0000220=IEA, GO:0033572=TAS, GO:0005737=IDA, GO:0030670=TAS, GO:0015991=IEA, GO:0051117=IPI, GO:0016021=IEA, GO:0090382=TAS, GO:0010008=TAS, GO:0033179=IEA} ATP hydrolysis coupled proton transport, cellular iron ion homeostasis, insulin receptor signaling pathway, interaction with host, phagosome maturation, transferrin transport, transmembrane transport Golgi apparatus, cytoplasm, endosome membrane, integral to membrane, intracellular membrane-bounded organelle, melanosome, nucleolus, nucleus, phagocytic vesicle membrane, plasma membrane, proton-transporting V-type ATPase, V0 domain, vacuolar proton-transporting V-type ATPase, V0 domain ATPase binding, hydrogen ion transmembrane transporter activity, protein binding Human ATP6V0A2 HPA UniProtKB {GO:0005515=PMID:16415858, GO:0008286=Reactome:REACT_498, GO:0005886=GO_REF:0000052, GO:0001669=GO_REF:0000019, GO:0051701=Reactome:REACT_121237, GO:0015078=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0000220=GO_REF:0000002, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0005737=GO_REF:0000052, GO:0006955=PMID:2247090, GO:0015991=GO_REF:0000002, GO:0030670=Reactome:REACT_121163, GO:0016021=GO_REF:0000037, GO:0090382=Reactome:REACT_121256, GO:0033179=GO_REF:0000002, GO:0010008=Reactome:REACT_25268} Q9Y487 V-type proton ATPase 116 kDa subunit a isoform 2 protein 20111111 {GO:0005515=IPI, GO:0008286=TAS, GO:0005886=IDA, GO:0001669=IEA, GO:0051701=TAS, GO:0015078=IEA, GO:0055085=TAS, GO:0000220=IEA, GO:0006879=TAS, GO:0033572=TAS, GO:0005737=IDA, GO:0006955=TAS, GO:0015991=IEA, GO:0030670=TAS, GO:0016021=IEA, GO:0090382=TAS, GO:0033179=IEA, GO:0010008=TAS} ATP hydrolysis coupled proton transport, cellular iron ion homeostasis, immune response, insulin receptor signaling pathway, interaction with host, phagosome maturation, transferrin transport, transmembrane transport acrosomal vesicle, cytoplasm, endosome membrane, integral to membrane, phagocytic vesicle membrane, plasma membrane, proton-transporting V-type ATPase, V0 domain, vacuolar proton-transporting V-type ATPase, V0 domain hydrogen ion transmembrane transporter activity, protein binding Human ATP6V0A4 Reactome UniProtKB {GO:0005515=PMID:12649290, GO:0008286=Reactome:REACT_498, GO:0005886=PMID:17360703, GO:0015078=GO_REF:0000002, GO:0007605=PMID:12414817, GO:0031526=PMID:14638902, GO:0006885=PMID:10973252, GO:0000220=GO_REF:0000002, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0016324=PMID:10973252, GO:0030670=Reactome:REACT_121163, GO:0051117=PMID:17360703, GO:0090382=Reactome:REACT_121256, GO:0007588=PMID:12414817, GO:0051701=Reactome:REACT_121237, GO:0045177=PMID:14638902, GO:0055085=Reactome:REACT_15518, GO:0001503=PMID:10973252, GO:0015991=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0016471=PMID:10973252, GO:0010008=Reactome:REACT_25268, GO:0005768=GO_REF:0000024, GO:0015992=PMID:10973252} Q9HBG4 V-type proton ATPase 116 kDa subunit a isoform 4 protein 20110228 {GO:0005515=IPI, GO:0008286=TAS, GO:0005886=IDA, GO:0015078=IEA, GO:0007605=IMP, GO:0031526=IDA, GO:0006885=IMP, GO:0000220=IEA, GO:0006879=TAS, GO:0033572=TAS, GO:0016324=IDA, GO:0030670=TAS, GO:0051117=IPI, GO:0090382=TAS, GO:0007588=IMP, GO:0051701=TAS, GO:0045177=IDA, GO:0055085=TAS, GO:0001503=IMP, GO:0015991=IEA, GO:0016021=IEA, GO:0016471=IDA, GO:0010008=TAS, GO:0005768=ISS, GO:0015992=IMP} ATP hydrolysis coupled proton transport, cellular iron ion homeostasis, excretion, insulin receptor signaling pathway, interaction with host, ossification, phagosome maturation, proton transport, regulation of pH, sensory perception of sound, transferrin transport, transmembrane transport apical part of cell, apical plasma membrane, brush border membrane, endosome, endosome membrane, integral to membrane, phagocytic vesicle membrane, plasma membrane, vacuolar proton-transporting V-type ATPase complex, vacuolar proton-transporting V-type ATPase, V0 domain ATPase binding, hydrogen ion transmembrane transporter activity, protein binding Human ATP6V0B Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005774=GO_REF:0000039, GO:0005215=PMID:9653649, GO:0051701=Reactome:REACT_121237, GO:0015078=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0015991=GO_REF:0000002, GO:0030670=Reactome:REACT_121163, GO:0016021=GO_REF:0000019, GO:0090382=Reactome:REACT_121256, GO:0033179=GO_REF:0000002, GO:0010008=Reactome:REACT_25268, GO:0005768=GO_REF:0000019, GO:0015992=PMID:9653649} Q99437 V-type proton ATPase 21 kDa proteolipid subunit protein 20110228 {GO:0008286=TAS, GO:0005774=IEA, GO:0005215=TAS, GO:0051701=TAS, GO:0015078=IEA, GO:0055085=TAS, GO:0006879=TAS, GO:0033572=TAS, GO:0015991=IEA, GO:0030670=TAS, GO:0016021=IEA, GO:0090382=TAS, GO:0033179=IEA, GO:0010008=TAS, GO:0005768=IEA, GO:0015992=TAS} ATP hydrolysis coupled proton transport, cellular iron ion homeostasis, insulin receptor signaling pathway, interaction with host, phagosome maturation, proton transport, transferrin transport, transmembrane transport endosome, endosome membrane, integral to membrane, phagocytic vesicle membrane, proton-transporting V-type ATPase, V0 domain, vacuolar membrane hydrogen ion transmembrane transporter activity, transporter activity Human ATP6V0C IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0008286=Reactome:REACT_498, GO:0005774=GO_REF:0000039, GO:0051701=Reactome:REACT_121237, GO:0015078=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0046961=PMID:1709739, GO:0019048=GO_REF:0000037, GO:0046933=PMID:1709739, GO:0030670=Reactome:REACT_121163, GO:0015991=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0090382=Reactome:REACT_121256, GO:0031625=PMID:18298843, GO:0010008=Reactome:REACT_25268, GO:0033179=GO_REF:0000002, GO:0015992=PMID:1709739} P27449 V-type proton ATPase 16 kDa proteolipid subunit protein 20130415 {GO:0005515=IPI, GO:0008286=TAS, GO:0005774=IEA, GO:0051701=TAS, GO:0015078=IEA, GO:0055085=TAS, GO:0006879=TAS, GO:0033572=TAS, GO:0046961=TAS, GO:0019048=IEA, GO:0046933=TAS, GO:0030670=TAS, GO:0015991=IEA, GO:0016021=IEA, GO:0090382=TAS, GO:0031625=IPI, GO:0010008=TAS, GO:0033179=IEA, GO:0015992=TAS} ATP hydrolysis coupled proton transport, cellular iron ion homeostasis, insulin receptor signaling pathway, interaction with host, phagosome maturation, proton transport, transferrin transport, transmembrane transport, virus-host interaction endosome membrane, integral to membrane, phagocytic vesicle membrane, proton-transporting V-type ATPase, V0 domain, vacuolar membrane hydrogen ion transmembrane transporter activity, protein binding, proton-transporting ATP synthase activity, rotational mechanism, proton-transporting ATPase activity, rotational mechanism, ubiquitin protein ligase binding Human UniProtKB:Q96G23 ATP6V0D1 Reactome UniProtKB {GO:0005515=PMID:18752060, GO:0008286=Reactome:REACT_498, GO:0015078=GO_REF:0000002, GO:0032403=GO_REF:0000019, GO:0030968=Reactome:REACT_18356, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0016324=GO_REF:0000019, GO:0008553=GO_REF:0000019, GO:0030670=Reactome:REACT_121163, GO:0043679=GO_REF:0000019, GO:0090382=Reactome:REACT_121256, GO:0033179=GO_REF:0000002, GO:0051701=Reactome:REACT_121237, GO:0055085=Reactome:REACT_15518, GO:0008021=GO_REF:0000019, GO:0016020=PMID:18752060, GO:0007420=GO_REF:0000019, GO:0015991=GO_REF:0000002, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0016471=PMID:18752060, GO:0005769=GO_REF:0000019, GO:0010008=Reactome:REACT_115786, GO:0015992=PMID:11118322} P61421 V-type proton ATPase subunit d 1 protein 20110228 {GO:0005515=IPI, GO:0008286=TAS, GO:0015078=IEA, GO:0032403=IEA, GO:0030968=TAS, GO:0006879=TAS, GO:0033572=TAS, GO:0016324=IEA, GO:0008553=IEA, GO:0030670=TAS, GO:0043679=IEA, GO:0090382=TAS, GO:0033179=IEA, GO:0051701=TAS, GO:0055085=TAS, GO:0008021=IEA, GO:0016020=IDA, GO:0007420=IEA, GO:0015991=IEA, GO:0006987=TAS, GO:0044267=TAS, GO:0016471=IDA, GO:0005769=IEA, GO:0010008=TAS, GO:0015992=NAS} ATP hydrolysis coupled proton transport, activation of signaling protein activity involved in unfolded protein response, brain development, cellular iron ion homeostasis, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, insulin receptor signaling pathway, interaction with host, phagosome maturation, proton transport, transferrin transport, transmembrane transport apical plasma membrane, axon terminus, early endosome, endosome membrane, membrane, phagocytic vesicle membrane, proton-transporting V-type ATPase, V0 domain, synaptic vesicle, vacuolar proton-transporting V-type ATPase complex hydrogen ion transmembrane transporter activity, hydrogen-exporting ATPase activity, phosphorylative mechanism, protein binding, protein complex binding Human ATP6V0D2 Reactome UniProtKB {GO:0005515=PMID:18752060, GO:0008286=Reactome:REACT_498, GO:0051701=Reactome:REACT_121237, GO:0015078=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0016324=PMID:15800125, GO:0016020=PMID:18752060, GO:0015991=GO_REF:0000002, GO:0030670=Reactome:REACT_121163, GO:0090382=Reactome:REACT_121256, GO:0010008=Reactome:REACT_25268, GO:0016471=PMID:18752060, GO:0005769=GO_REF:0000019, GO:0033179=GO_REF:0000002} Q8N8Y2 V-type proton ATPase subunit d 2 protein 20110228 {GO:0005515=IPI, GO:0008286=TAS, GO:0051701=TAS, GO:0015078=IEA, GO:0055085=TAS, GO:0006879=TAS, GO:0033572=TAS, GO:0016324=IDA, GO:0016020=IDA, GO:0015991=IEA, GO:0030670=TAS, GO:0090382=TAS, GO:0010008=TAS, GO:0016471=IDA, GO:0005769=IEA, GO:0033179=IEA} ATP hydrolysis coupled proton transport, cellular iron ion homeostasis, insulin receptor signaling pathway, interaction with host, phagosome maturation, transferrin transport, transmembrane transport apical plasma membrane, early endosome, endosome membrane, membrane, phagocytic vesicle membrane, proton-transporting V-type ATPase, V0 domain, vacuolar proton-transporting V-type ATPase complex hydrogen ion transmembrane transporter activity, protein binding Human ATP6V0E1 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005215=PMID:9556572, GO:0051701=Reactome:REACT_121237, GO:0015078=GO_REF:0000002, GO:0042625=GO_REF:0000024, GO:0055085=Reactome:REACT_15518, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0016020=PMID:9556572, GO:0007035=GO_REF:0000024, GO:0046961=PMID:9556572, GO:0030670=Reactome:REACT_121163, GO:0015991=GO_REF:0000002, GO:0016049=PMID:17350184, GO:0016021=GO_REF:0000037, GO:0090382=Reactome:REACT_121256, GO:0043200=GO_REF:0000019, GO:0010008=Reactome:REACT_25268, GO:0033179=GO_REF:0000002, GO:0015992=PMID:9556572} O15342 V-type proton ATPase subunit e 1 protein 20110228 {GO:0008286=TAS, GO:0005215=NAS, GO:0051701=TAS, GO:0015078=IEA, GO:0042625=ISS, GO:0055085=TAS, GO:0006879=TAS, GO:0033572=TAS, GO:0016020=TAS, GO:0007035=ISS, GO:0046961=TAS, GO:0030670=TAS, GO:0015991=IEA, GO:0016049=IGI, GO:0016021=IEA, GO:0090382=TAS, GO:0043200=IEA, GO:0010008=TAS, GO:0033179=IEA, GO:0015992=TAS} ATP hydrolysis coupled proton transport, cell growth, cellular iron ion homeostasis, insulin receptor signaling pathway, interaction with host, phagosome maturation, proton transport, response to amino acid stimulus, transferrin transport, transmembrane transport, vacuolar acidification endosome membrane, integral to membrane, membrane, phagocytic vesicle membrane, proton-transporting V-type ATPase, V0 domain ATPase activity, coupled to transmembrane movement of ions, hydrogen ion transmembrane transporter activity, proton-transporting ATPase activity, rotational mechanism, transporter activity Human ATP6V1A Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0046034=GO_REF:0000002, GO:0051701=Reactome:REACT_121237, GO:0005886=GO_REF:0000024, GO:0016469=PMID:8463241, GO:0033180=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_121163, GO:0006879=Reactome:REACT_25060, GO:0005739=GO_REF:0000019, GO:0033572=Reactome:REACT_25283, GO:0005902=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0046961=GO_REF:0000002, GO:0005887=PMID:8463241, GO:0006810=PMID:8463241, GO:0015991=GO_REF:0000002, GO:0090382=Reactome:REACT_121256, GO:0015992=GO_REF:0000002} P38606 V-type proton ATPase catalytic subunit A protein 20100712 {GO:0008286=TAS, GO:0046034=IEA, GO:0051701=TAS, GO:0005886=ISS, GO:0016469=TAS, GO:0033180=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0005829=TAS, GO:0006879=TAS, GO:0005739=IEA, GO:0033572=TAS, GO:0005902=IEA, GO:0016324=IEA, GO:0046961=IEA, GO:0005887=TAS, GO:0006810=TAS, GO:0015991=IEA, GO:0090382=TAS, GO:0015992=IEA} ATP hydrolysis coupled proton transport, ATP metabolic process, cellular iron ion homeostasis, insulin receptor signaling pathway, interaction with host, phagosome maturation, proton transport, transferrin transport, transmembrane transport, transport apical plasma membrane, cytosol, integral to plasma membrane, microvillus, mitochondrion, plasma membrane, proton-transporting V-type ATPase, V1 domain, proton-transporting two-sector ATPase complex ATP binding, proton-transporting ATPase activity, rotational mechanism Human ATP6V1B1 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0015078=PMID:14585495, GO:0007605=PMID:9916796, GO:0045851=PMID:19478356, GO:0033180=GO_REF:0000002, GO:0032403=GO_REF:0000019, GO:0006885=PMID:12414817, GO:0055074=PMID:19478356, GO:0005829=Reactome:REACT_121163, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0016323=PMID:14585495, GO:0016324=PMID:16928804, GO:0005737=PMID:14585495, GO:0016820=GO_REF:0000002, GO:0090382=Reactome:REACT_121256, GO:0033178=GO_REF:0000002, GO:0007588=PMID:12414817, GO:0046034=GO_REF:0000002, GO:0042472=PMID:19639346, GO:0051701=Reactome:REACT_121237, GO:0055085=Reactome:REACT_15518, GO:0016328=PMID:14585495, GO:0005524=GO_REF:0000002, GO:0012505=GO_REF:0000039, GO:0005902=PMID:14585495, GO:0001503=PMID:16433694, GO:0015991=GO_REF:0000002, GO:0016471=PMID:12414817, GO:0015992=PMID:12414817} P15313 V-type proton ATPase subunit B, kidney isoform protein 20130301 {GO:0008286=TAS, GO:0015078=ISS, GO:0007605=IMP, GO:0045851=IMP, GO:0033180=IEA, GO:0032403=IEA, GO:0006885=IMP, GO:0055074=IMP, GO:0005829=TAS, GO:0006879=TAS, GO:0033572=TAS, GO:0016323=ISS, GO:0016324=IDA, GO:0005737=ISS, GO:0016820=IEA, GO:0090382=TAS, GO:0033178=IEA, GO:0007588=IMP, GO:0046034=IEA, GO:0042472=IMP, GO:0051701=TAS, GO:0055085=TAS, GO:0016328=ISS, GO:0005524=IEA, GO:0012505=IEA, GO:0005902=ISS, GO:0001503=IMP, GO:0015991=IEA, GO:0016471=IMP, GO:0015992=IMP} ATP hydrolysis coupled proton transport, ATP metabolic process, calcium ion homeostasis, cellular iron ion homeostasis, excretion, inner ear morphogenesis, insulin receptor signaling pathway, interaction with host, ossification, pH reduction, phagosome maturation, proton transport, regulation of pH, sensory perception of sound, transferrin transport, transmembrane transport apical plasma membrane, basolateral plasma membrane, cytoplasm, cytosol, endomembrane system, lateral plasma membrane, microvillus, proton-transporting V-type ATPase, V1 domain, proton-transporting two-sector ATPase complex, catalytic domain, vacuolar proton-transporting V-type ATPase complex ATP binding, hydrogen ion transmembrane transporter activity, hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances, protein complex binding Human ATP6V1B2 HPA UniProtKB {GO:0008286=Reactome:REACT_498, GO:0042470=GO_REF:0000039, GO:0046034=GO_REF:0000002, GO:0005794=GO_REF:0000052, GO:0051701=Reactome:REACT_121237, GO:0005886=GO_REF:0000024, GO:0015078=PMID:2145275, GO:0033180=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000002, GO:0005829=Reactome:REACT_121163, GO:0043231=GO_REF:0000052, GO:0012505=GO_REF:0000039, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0005902=GO_REF:0000019, GO:0046961=PMID:2145275, GO:0015991=GO_REF:0000002, GO:0016820=GO_REF:0000002, GO:0016021=GO_REF:0000019, GO:0090382=Reactome:REACT_121256, GO:0015992=PMID:2145275, GO:0033178=GO_REF:0000002} P21281 V-type proton ATPase subunit B, brain isoform protein 20090616 {GO:0008286=TAS, GO:0042470=IEA, GO:0046034=IEA, GO:0005794=IDA, GO:0051701=TAS, GO:0005886=ISS, GO:0015078=TAS, GO:0033180=IEA, GO:0055085=TAS, GO:0005524=IEA, GO:0005829=TAS, GO:0043231=IDA, GO:0012505=IEA, GO:0006879=TAS, GO:0033572=TAS, GO:0005902=IEA, GO:0046961=TAS, GO:0015991=IEA, GO:0016820=IEA, GO:0016021=IEA, GO:0090382=TAS, GO:0015992=TAS, GO:0033178=IEA} ATP hydrolysis coupled proton transport, ATP metabolic process, cellular iron ion homeostasis, insulin receptor signaling pathway, interaction with host, phagosome maturation, proton transport, transferrin transport, transmembrane transport Golgi apparatus, cytosol, endomembrane system, integral to membrane, intracellular membrane-bounded organelle, melanosome, microvillus, plasma membrane, proton-transporting V-type ATPase, V1 domain, proton-transporting two-sector ATPase complex, catalytic domain ATP binding, hydrogen ion transmembrane transporter activity, hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances, proton-transporting ATPase activity, rotational mechanism Human ATP6V1C1 IntAct UniProtKB {GO:0005515=PMID:16415858, GO:0008286=Reactome:REACT_498, GO:0005215=PMID:8250920, GO:0051701=Reactome:REACT_121237, GO:0005886=GO_REF:0000024, GO:0016469=PMID:8250920, GO:0033180=GO_REF:0000002, GO:0045177=GO_REF:0000019, GO:0031410=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0005829=Reactome:REACT_121163, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0008553=GO_REF:0000019, GO:0046961=PMID:8250920, GO:0015991=GO_REF:0000002, GO:0090382=Reactome:REACT_121256, GO:0015992=PMID:8250920} P21283 V-type proton ATPase subunit C 1 protein 20130415 {GO:0005515=IPI, GO:0008286=TAS, GO:0005215=NAS, GO:0051701=TAS, GO:0005886=ISS, GO:0016469=TAS, GO:0033180=IEA, GO:0045177=IEA, GO:0031410=IEA, GO:0055085=TAS, GO:0005829=TAS, GO:0006879=TAS, GO:0033572=TAS, GO:0008553=IEA, GO:0046961=TAS, GO:0015991=IEA, GO:0090382=TAS, GO:0015992=TAS} ATP hydrolysis coupled proton transport, cellular iron ion homeostasis, insulin receptor signaling pathway, interaction with host, phagosome maturation, proton transport, transferrin transport, transmembrane transport apical part of cell, cytoplasmic vesicle, cytosol, plasma membrane, proton-transporting V-type ATPase, V1 domain, proton-transporting two-sector ATPase complex hydrogen-exporting ATPase activity, phosphorylative mechanism, protein binding, proton-transporting ATPase activity, rotational mechanism, transporter activity Human UniProtKB:P62330 ATP6V1D Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0006879=Reactome:REACT_25060, GO:0005515=PMID:18752060, GO:0033572=Reactome:REACT_25283, GO:0051701=Reactome:REACT_121237, GO:0016020=PMID:18752060, GO:0042626=GO_REF:0000002, GO:0090382=Reactome:REACT_121256, GO:0055085=Reactome:REACT_15518, GO:0016471=PMID:18752060, GO:0005829=Reactome:REACT_121163, GO:0015992=GO_REF:0000037} Q9Y5K8 V-type proton ATPase subunit D protein 20100712 {GO:0008286=TAS, GO:0006879=TAS, GO:0005515=IPI, GO:0033572=TAS, GO:0051701=TAS, GO:0016020=IDA, GO:0042626=IEA, GO:0090382=TAS, GO:0055085=TAS, GO:0016471=IDA, GO:0005829=TAS, GO:0015992=IEA} cellular iron ion homeostasis, insulin receptor signaling pathway, interaction with host, phagosome maturation, proton transport, transferrin transport, transmembrane transport cytosol, membrane, vacuolar proton-transporting V-type ATPase complex ATPase activity, coupled to transmembrane movement of substances, protein binding Human ATP6V1E1 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005515=PMID:21784977, GO:0051701=Reactome:REACT_121237, GO:0016469=PMID:8250920, GO:0055085=Reactome:REACT_15518, GO:0005829=Reactome:REACT_121163, GO:0005739=GO_REF:0000019, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0005902=GO_REF:0000019, GO:0016324=GO_REF:0000024, GO:0008553=GO_REF:0000019, GO:0046961=GO_REF:0000002, GO:0015991=GO_REF:0000019, GO:0090382=Reactome:REACT_121256, GO:0005768=GO_REF:0000024, GO:0015992=PMID:8250920, GO:0033178=GO_REF:0000002} P36543 V-type proton ATPase subunit E 1 protein 20130301 {GO:0008286=TAS, GO:0005515=IPI, GO:0051701=TAS, GO:0016469=TAS, GO:0055085=TAS, GO:0005829=TAS, GO:0005739=IEA, GO:0006879=TAS, GO:0033572=TAS, GO:0005902=IEA, GO:0016324=ISS, GO:0008553=IEA, GO:0046961=IEA, GO:0015991=IEA, GO:0090382=TAS, GO:0005768=ISS, GO:0015992=TAS, GO:0033178=IEA} ATP hydrolysis coupled proton transport, cellular iron ion homeostasis, insulin receptor signaling pathway, interaction with host, phagosome maturation, proton transport, transferrin transport, transmembrane transport apical plasma membrane, cytosol, endosome, microvillus, mitochondrion, proton-transporting two-sector ATPase complex, proton-transporting two-sector ATPase complex, catalytic domain hydrogen-exporting ATPase activity, phosphorylative mechanism, protein binding, proton-transporting ATPase activity, rotational mechanism Human ATP6V1E2 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0051701=Reactome:REACT_121237, GO:0008553=GO_REF:0000019, GO:0001669=GO_REF:0000019, GO:0046961=GO_REF:0000002, GO:0015991=GO_REF:0000019, GO:0090382=Reactome:REACT_121256, GO:0055085=Reactome:REACT_15518, GO:0005829=Reactome:REACT_121163, GO:0033178=GO_REF:0000002} Q96A05 V-type proton ATPase subunit E 2 protein 20130301 {GO:0008286=TAS, GO:0006879=TAS, GO:0033572=TAS, GO:0051701=TAS, GO:0008553=IEA, GO:0001669=IEA, GO:0046961=IEA, GO:0015991=IEA, GO:0090382=TAS, GO:0055085=TAS, GO:0005829=TAS, GO:0033178=IEA} ATP hydrolysis coupled proton transport, cellular iron ion homeostasis, insulin receptor signaling pathway, interaction with host, phagosome maturation, transferrin transport, transmembrane transport acrosomal vesicle, cytosol, proton-transporting two-sector ATPase complex, catalytic domain hydrogen-exporting ATPase activity, phosphorylative mechanism, proton-transporting ATPase activity, rotational mechanism Human ATP6V1F Reactome UniProtKB {GO:0005515=PMID:18752060, GO:0008286=Reactome:REACT_498, GO:0051701=Reactome:REACT_121237, GO:0015078=PMID:8581736, GO:0016469=PMID:8581736, GO:0033180=GO_REF:0000002, GO:0042624=PMID:8581736, GO:0055085=Reactome:REACT_15518, GO:0005829=Reactome:REACT_121163, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0016020=PMID:18752060, GO:0046961=GO_REF:0000002, GO:0015991=GO_REF:0000002, GO:0090382=Reactome:REACT_121256, GO:0016471=PMID:18752060, GO:0015992=PMID:8581736} Q16864 V-type proton ATPase subunit F protein 20130213 {GO:0005515=IPI, GO:0008286=TAS, GO:0051701=TAS, GO:0015078=NAS, GO:0016469=NAS, GO:0033180=IEA, GO:0042624=NAS, GO:0055085=TAS, GO:0005829=TAS, GO:0006879=TAS, GO:0033572=TAS, GO:0016020=IDA, GO:0046961=IEA, GO:0015991=IEA, GO:0090382=TAS, GO:0016471=IDA, GO:0015992=NAS} ATP hydrolysis coupled proton transport, cellular iron ion homeostasis, insulin receptor signaling pathway, interaction with host, phagosome maturation, proton transport, transferrin transport, transmembrane transport cytosol, membrane, proton-transporting V-type ATPase, V1 domain, proton-transporting two-sector ATPase complex, vacuolar proton-transporting V-type ATPase complex ATPase activity, uncoupled, hydrogen ion transmembrane transporter activity, protein binding, proton-transporting ATPase activity, rotational mechanism Human ATP6V1G1 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0051701=Reactome:REACT_121237, GO:0005886=GO_REF:0000024, GO:0051117=PMID:17360703, GO:0016820=GO_REF:0000002, GO:0090382=Reactome:REACT_121256, GO:0055085=Reactome:REACT_15518, GO:0016471=GO_REF:0000002, GO:0005829=Reactome:REACT_121163, GO:0015992=GO_REF:0000037} O75348 V-type proton ATPase subunit G 1 protein 20130301 {GO:0008286=TAS, GO:0006879=TAS, GO:0033572=TAS, GO:0051701=TAS, GO:0005886=ISS, GO:0051117=IPI, GO:0016820=IEA, GO:0090382=TAS, GO:0055085=TAS, GO:0016471=IEA, GO:0005829=TAS, GO:0015992=IEA} cellular iron ion homeostasis, insulin receptor signaling pathway, interaction with host, phagosome maturation, proton transport, transferrin transport, transmembrane transport cytosol, plasma membrane, vacuolar proton-transporting V-type ATPase complex ATPase binding, hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances Human ATP6V1G2 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0042470=GO_REF:0000039, GO:0051701=Reactome:REACT_121237, GO:0016820=GO_REF:0000002, GO:0090382=Reactome:REACT_121256, GO:0055085=Reactome:REACT_15518, GO:0016471=GO_REF:0000002, GO:0005829=Reactome:REACT_121163, GO:0015992=GO_REF:0000037} O95670 V-type proton ATPase subunit G 2 protein 20130301 {GO:0008286=TAS, GO:0006879=TAS, GO:0033572=TAS, GO:0042470=IEA, GO:0051701=TAS, GO:0016820=IEA, GO:0090382=TAS, GO:0055085=TAS, GO:0016471=IEA, GO:0005829=TAS, GO:0015992=IEA} cellular iron ion homeostasis, insulin receptor signaling pathway, interaction with host, phagosome maturation, proton transport, transferrin transport, transmembrane transport cytosol, melanosome, vacuolar proton-transporting V-type ATPase complex hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances Human ATP6V1H GOC UniProtKB {GO:0005515=PMID:9620685, GO:0008286=Reactome:REACT_498, GO:0006200=PMID:9442887, GO:0051701=Reactome:REACT_121237, GO:0005886=Reactome:REACT_11160, GO:0055085=Reactome:REACT_15518, GO:0050690=Reactome:REACT_11200, GO:0006897=PMID:12032142, GO:0005829=Reactome:REACT_121163, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0000221=PMID:9442887, GO:0050790=PMID:9442887, GO:0046961=GO_REF:0000002, GO:0007035=PMID:9442887, GO:0019048=GO_REF:0000037, GO:0015991=PMID:9442887, GO:0016032=Reactome:REACT_6185, GO:0030234=PMID:9442887, GO:0090382=Reactome:REACT_121256, GO:0016887=PMID:9442887} Q9UI12 V-type proton ATPase subunit H protein 20130413 {GO:0005515=IPI, GO:0008286=TAS, GO:0006200=NAS, GO:0051701=TAS, GO:0005886=TAS, GO:0055085=TAS, GO:0050690=TAS, GO:0006897=IDA, GO:0005829=TAS, GO:0006879=TAS, GO:0033572=TAS, GO:0000221=NAS, GO:0050790=NAS, GO:0046961=IEA, GO:0007035=NAS, GO:0019048=IEA, GO:0015991=NAS, GO:0016032=TAS, GO:0030234=NAS, GO:0090382=TAS, GO:0016887=NAS} ATP catabolic process, ATP hydrolysis coupled proton transport, cellular iron ion homeostasis, endocytosis, insulin receptor signaling pathway, interaction with host, phagosome maturation, regulation of catalytic activity, regulation of defense response to virus by virus, transferrin transport, transmembrane transport, vacuolar acidification, viral reproduction, virus-host interaction cytosol, plasma membrane, vacuolar proton-transporting V-type ATPase, V1 domain ATPase activity, enzyme regulator activity, protein binding, proton-transporting ATPase activity, rotational mechanism Human ATP7A Reactome UniProtKB {GO:0005515=PMID:16884690, GO:0005802=PMID:12812980, GO:0010468=GO_REF:0000019, GO:0051353=PMID:11092760, GO:0051216=GO_REF:0000024, GO:0031526=GO_REF:0000019, GO:0018205=GO_REF:0000024, GO:0051542=GO_REF:0000024, GO:0010043=GO_REF:0000019, GO:0021860=GO_REF:0000024, GO:0010041=GO_REF:0000019, GO:0031069=GO_REF:0000024, GO:0043524=GO_REF:0000019, GO:0034220=Reactome:REACT_25300, GO:0006878=PMID:16397091, GO:0030198=GO_REF:0000024, GO:0019430=GO_REF:0000024, GO:0030199=GO_REF:0000024, GO:0043025=GO_REF:0000024, GO:0060003=GO_REF:0000024, GO:0048251=GO_REF:0000024, GO:0032767=PMID:10497213, GO:0005794=PMID:9467005, GO:0048286=GO_REF:0000024, GO:0005507=PMID:15670166, GO:0043085=GO_REF:0000024, GO:0001701=GO_REF:0000019, GO:0048553=GO_REF:0000024, GO:0048554=GO_REF:0000024, GO:0006584=GO_REF:0000024, GO:0043588=GO_REF:0000024, GO:0007005=GO_REF:0000024, GO:0043005=GO_REF:0000024, GO:0048471=PMID:16397091, GO:0005886=Reactome:REACT_25071, GO:0005783=GO_REF:0000039, GO:0001836=GO_REF:0000019, GO:0005829=GO_REF:0000039, GO:0016323=PMID:16397091, GO:0042093=GO_REF:0000024, GO:0042415=GO_REF:0000024, GO:0042417=GO_REF:0000024, GO:0006570=GO_REF:0000019, GO:0005375=GO_REF:0000024, GO:0021702=GO_REF:0000024, GO:0015677=GO_REF:0000024, GO:0007626=GO_REF:0000024, GO:0030141=GO_REF:0000019, GO:0030140=PMID:9817923, GO:0042414=GO_REF:0000024, GO:0002082=GO_REF:0000024, GO:0001568=GO_REF:0000024, GO:0005770=PMID:8943055, GO:0021954=GO_REF:0000024, GO:0016532=GO_REF:0000024, GO:0055085=Reactome:REACT_15518, GO:0005524=PMID:9817923, GO:0004008=GO_REF:0000024, GO:0010273=GO_REF:0000024, GO:0042428=GO_REF:0000024, GO:0048813=GO_REF:0000019, GO:0001974=GO_REF:0000024, GO:0048812=GO_REF:0000024, GO:0043473=GO_REF:0000024, GO:0042421=GO_REF:0000019, GO:0016021=GO_REF:0000019, GO:0006825=PMID:11092760, GO:0006568=GO_REF:0000024} Q04656 Copper-transporting ATPase 1 protein 20130301 {GO:0005515=IPI, GO:0005802=IDA, GO:0010468=IEA, GO:0051353=IDA, GO:0051216=ISS, GO:0031526=IEA, GO:0018205=ISS, GO:0051542=ISS, GO:0010043=IEA, GO:0021860=ISS, GO:0010041=IEA, GO:0031069=ISS, GO:0043524=IEA, GO:0034220=TAS, GO:0006878=IMP, GO:0030198=ISS, GO:0019430=ISS, GO:0030199=ISS, GO:0043025=ISS, GO:0060003=ISS, GO:0048251=ISS, GO:0032767=IPI, GO:0005794=IDA, GO:0048286=ISS, GO:0005507=IDA, GO:0043085=ISS, GO:0001701=IEA, GO:0048553=ISS, GO:0048554=ISS, GO:0006584=ISS, GO:0043588=ISS, GO:0007005=ISS, GO:0043005=ISS, GO:0048471=IDA, GO:0005886=TAS, GO:0005783=IEA, GO:0001836=IEA, GO:0005829=IEA, GO:0016323=IDA, GO:0042093=ISS, GO:0042415=ISS, GO:0042417=ISS, GO:0006570=IEA, GO:0005375=ISS, GO:0021702=ISS, GO:0015677=ISS, GO:0007626=ISS, GO:0030141=IEA, GO:0030140=IMP, GO:0042414=ISS, GO:0002082=ISS, GO:0001568=ISS, GO:0005770=IDA, GO:0021954=ISS, GO:0016532=ISS, GO:0055085=TAS, GO:0005524=TAS, GO:0004008=ISS, GO:0010273=ISS, GO:0042428=ISS, GO:0048813=IEA, GO:0001974=ISS, GO:0048812=ISS, GO:0043473=ISS, GO:0042421=IEA, GO:0016021=IEA, GO:0006825=IMP, GO:0006568=ISS} T-helper cell differentiation, blood vessel development, blood vessel remodeling, cartilage development, catecholamine metabolic process, cellular copper ion homeostasis, central nervous system neuron development, cerebellar Purkinje cell differentiation, collagen fibril organization, copper ion export, copper ion import, copper ion transport, dendrite morphogenesis, detoxification of copper ion, dopamine metabolic process, elastic fiber assembly, elastin biosynthetic process, epinephrine metabolic process, extracellular matrix organization, hair follicle morphogenesis, in utero embryonic development, ion transmembrane transport, locomotory behavior, lung alveolus development, mitochondrion organization, negative regulation of metalloenzyme activity, negative regulation of neuron apoptotic process, neuron projection morphogenesis, norepinephrine biosynthetic process, norepinephrine metabolic process, peptidyl-lysine modification, pigmentation, positive regulation of catalytic activity, positive regulation of metalloenzyme activity, positive regulation of oxidoreductase activity, pyramidal neuron development, regulation of gene expression, regulation of oxidative phosphorylation, release of cytochrome c from mitochondria, removal of superoxide radicals, response to iron(III) ion, response to zinc ion, serotonin metabolic process, skin development, transmembrane transport, tryptophan metabolic process, tyrosine metabolic process Golgi apparatus, basolateral plasma membrane, brush border membrane, cytosol, endoplasmic reticulum, integral to membrane, late endosome, neuron projection, neuronal cell body, perinuclear region of cytoplasm, plasma membrane, secretory granule, trans-Golgi network, trans-Golgi network transport vesicle ATP binding, copper ion binding, copper ion transmembrane transporter activity, copper-dependent protein binding, copper-exporting ATPase activity, protein binding, superoxide dismutase copper chaperone activity Human ATP7B Reactome UniProtKB {GO:0005802=PMID:15269005, GO:0005515=PMID:16554302, GO:0048471=PMID:16939419, GO:0006882=GO_REF:0000019, GO:0046872=GO_REF:0000002, GO:0015680=GO_REF:0000019, GO:0005739=GO_REF:0000039, GO:0016323=PMID:15269005, GO:0006878=PMID:16554302, GO:0034220=Reactome:REACT_25300, GO:0000166=GO_REF:0000002, GO:0015677=PMID:16472602, GO:0051208=PMID:16472602, GO:0005507=PMID:14709553, GO:0005770=PMID:15681833, GO:0055085=Reactome:REACT_15518, GO:0005524=PMID:15205462, GO:0004008=PMID:12763797, GO:0019829=GO_REF:0000002, GO:0007595=GO_REF:0000019, GO:0000139=Reactome:REACT_24963, GO:0005887=PMID:8298641, GO:0016023=PMID:16472602, GO:0016021=GO_REF:0000038, GO:0046688=PMID:15269005, GO:0006825=PMID:12572677} P35670 Copper-transporting ATPase 2 protein 20130301 {GO:0005802=IDA, GO:0005515=IPI, GO:0048471=IDA, GO:0006882=IEA, GO:0046872=IEA, GO:0015680=IEA, GO:0005739=IEA, GO:0016323=IDA, GO:0006878=TAS, GO:0034220=TAS, GO:0000166=IEA, GO:0015677=IDA, GO:0051208=IDA, GO:0005507=IDA, GO:0005770=IDA, GO:0055085=TAS, GO:0005524=IDA, GO:0004008=NAS, GO:0019829=IEA, GO:0007595=IEA, GO:0000139=TAS, GO:0005887=TAS, GO:0016023=IDA, GO:0016021=IEA, GO:0046688=IDA, GO:0006825=IGI} cellular copper ion homeostasis, cellular zinc ion homeostasis, copper ion import, copper ion transport, intracellular copper ion transport, ion transmembrane transport, lactation, response to copper ion, sequestering of calcium ion, transmembrane transport Golgi membrane, basolateral plasma membrane, cytoplasmic membrane-bounded vesicle, integral to membrane, integral to plasma membrane, late endosome, mitochondrion, perinuclear region of cytoplasm, trans-Golgi network ATP binding, cation-transporting ATPase activity, copper ion binding, copper-exporting ATPase activity, metal ion binding, nucleotide binding, protein binding Human ATP8A1 Reactome UniProtKB {GO:0005515=PMID:21914794, GO:0015247=GO_REF:0000029, GO:0000287=GO_REF:0000002, GO:0005886=Reactome:REACT_115892, GO:0005783=PMID:21914794, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000029, GO:0045332=PMID:21914794, GO:0019829=PMID:10198212, GO:0034220=Reactome:REACT_25300, GO:0042584=GO_REF:0000039, GO:0004012=GO_REF:0000003, GO:0016021=GO_REF:0000029, GO:0015917=GO_REF:0000029} Q9Y2Q0 Probable phospholipid-transporting ATPase IA protein 20130301 {GO:0005515=IPI, GO:0015247=NAS, GO:0000287=IEA, GO:0005886=TAS, GO:0005783=IDA, GO:0055085=TAS, GO:0005524=NAS, GO:0045332=NAS, GO:0019829=NAS, GO:0034220=TAS, GO:0042584=IEA, GO:0004012=IEA, GO:0016021=NAS, GO:0015917=NAS} aminophospholipid transport, ion transmembrane transport, phospholipid translocation, transmembrane transport chromaffin granule membrane, endoplasmic reticulum, integral to membrane, plasma membrane ATP binding, aminophospholipid transporter activity, cation-transporting ATPase activity, magnesium ion binding, phospholipid-translocating ATPase activity, protein binding Human ATP8A2 PINC UniProtKB {GO:0019829=GO_REF:0000002, GO:0008285=PMID:10551800, GO:0000287=GO_REF:0000002, GO:0004012=GO_REF:0000003, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0031175=GO_REF:0000019} Q9NTI2 Probable phospholipid-transporting ATPase IB protein 20050308 {GO:0019829=IEA, GO:0008285=TAS, GO:0000287=IEA, GO:0004012=IEA, GO:0016021=IEA, GO:0005524=IEA, GO:0031175=IEA} negative regulation of cell proliferation, neuron projection development integral to membrane ATP binding, cation-transporting ATPase activity, magnesium ion binding, phospholipid-translocating ATPase activity Human ATP8B2 GOC UniProtKB {GO:0019829=GO_REF:0000002, GO:0034220=Reactome:REACT_25300, GO:0000287=GO_REF:0000002, GO:0006200=PMID:12880872, GO:0005886=Reactome:REACT_115892, GO:0004012=GO_REF:0000003, GO:0016021=PMID:12880872, GO:0055085=Reactome:REACT_15518, GO:0016887=PMID:12880872, GO:0005524=GO_REF:0000037} P98198 Probable phospholipid-transporting ATPase ID protein 20130413 {GO:0019829=IEA, GO:0034220=TAS, GO:0000287=IEA, GO:0006200=RCA, GO:0005886=TAS, GO:0004012=IEA, GO:0016021=RCA, GO:0055085=TAS, GO:0016887=RCA, GO:0005524=IEA} ATP catabolic process, ion transmembrane transport, transmembrane transport integral to membrane, plasma membrane ATP binding, ATPase activity, cation-transporting ATPase activity, magnesium ion binding, phospholipid-translocating ATPase activity Human ATP8B3 GOC UniProtKB {GO:0019829=GO_REF:0000002, GO:0000287=GO_REF:0000002, GO:0006200=PMID:12880872, GO:0001669=GO_REF:0000019, GO:0004012=GO_REF:0000003, GO:0016021=PMID:12880872, GO:0007339=GO_REF:0000019, GO:0016887=PMID:12880872, GO:0005524=GO_REF:0000037, GO:0045332=GO_REF:0000019} O60423 Probable phospholipid-transporting ATPase IK protein 20130413 {GO:0019829=IEA, GO:0000287=IEA, GO:0006200=RCA, GO:0001669=IEA, GO:0004012=IEA, GO:0016021=RCA, GO:0007339=IEA, GO:0016887=RCA, GO:0005524=IEA, GO:0045332=IEA} ATP catabolic process, binding of sperm to zona pellucida, phospholipid translocation acrosomal vesicle, integral to membrane ATP binding, ATPase activity, cation-transporting ATPase activity, magnesium ion binding, phospholipid-translocating ATPase activity Human ATP9A UniProtKB UniProtKB {GO:0005802=PMID:21914794, GO:0019829=GO_REF:0000002, GO:0048471=PMID:21914794, GO:0005794=GO_REF:0000039, GO:0000287=GO_REF:0000002, GO:0031901=GO_REF:0000039, GO:0004012=GO_REF:0000003, GO:0016021=GO_REF:0000037, GO:0055037=PMID:21914794, GO:0005524=GO_REF:0000037, GO:0045332=PMID:21914794, GO:0005769=PMID:21914794} O75110 Probable phospholipid-transporting ATPase IIA protein 20110922 {GO:0005802=IDA, GO:0019829=IEA, GO:0048471=IDA, GO:0005794=IEA, GO:0000287=IEA, GO:0031901=IEA, GO:0004012=IEA, GO:0016021=IEA, GO:0055037=IDA, GO:0005524=IEA, GO:0045332=NAS, GO:0005769=IDA} phospholipid translocation Golgi apparatus, early endosome, early endosome membrane, integral to membrane, perinuclear region of cytoplasm, recycling endosome, trans-Golgi network ATP binding, cation-transporting ATPase activity, magnesium ion binding, phospholipid-translocating ATPase activity Human ATP9B UniProtKB UniProtKB {GO:0005802=PMID:21914794, GO:0019829=GO_REF:0000029, GO:0048471=PMID:21914794, GO:0015247=GO_REF:0000029, GO:0005794=GO_REF:0000039, GO:0000287=GO_REF:0000002, GO:0004012=GO_REF:0000003, GO:0072600=PMID:21914794, GO:0015917=GO_REF:0000029, GO:0016021=GO_REF:0000029, GO:0005524=GO_REF:0000029, GO:0045332=PMID:21914794} O43861 Probable phospholipid-transporting ATPase IIB protein 20110922 {GO:0005802=IDA, GO:0019829=NAS, GO:0048471=IDA, GO:0015247=NAS, GO:0005794=IEA, GO:0000287=IEA, GO:0004012=IEA, GO:0072600=IMP, GO:0015917=NAS, GO:0016021=NAS, GO:0005524=NAS, GO:0045332=NAS} aminophospholipid transport, establishment of protein localization to Golgi, phospholipid translocation Golgi apparatus, integral to membrane, perinuclear region of cytoplasm, trans-Golgi network ATP binding, aminophospholipid transporter activity, cation-transporting ATPase activity, magnesium ion binding, phospholipid-translocating ATPase activity Human ATPAF1 UniProtKB UniProtKB {GO:0005515=PMID:11410595, GO:0005739=GO_REF:0000039, GO:0006461=GO_REF:0000002} Q5TC12 ATP synthase mitochondrial F1 complex assembly factor 1 protein 20091116 {GO:0005515=IPI, GO:0005739=IEA, GO:0006461=IEA} protein complex assembly mitochondrion protein binding Human UniProtKB:P06576 ATPAF2 LIFEdb UniProtKB {GO:0005515=PMID:11410595, GO:0005739=GO_REF:0000039, GO:0016607=GO_REF:0000054, GO:0043461=PMID:14757859} Q8N5M1 ATP synthase mitochondrial F1 complex assembly factor 2 protein 20100607 {GO:0005515=IPI, GO:0005739=IEA, GO:0016607=IDA, GO:0043461=NAS} proton-transporting ATP synthase complex assembly mitochondrion, nuclear speck protein binding Human ATPBD4 UniProtKB UniProtKB {GO:0017178=PMID:23169644, GO:0005524=GO_REF:0000037, GO:0017183=PMID:23169644} Q7L8W6 Diphthine--ammonia ligase protein 20130118 {GO:0017178=TAS, GO:0005524=IEA, GO:0017183=TAS} peptidyl-diphthamide biosynthetic process from peptidyl-histidine ATP binding, diphthine-ammonia ligase activity Human ATPIF1 HPA UniProtKB {GO:0004857=PMID:10664857, GO:0005516=GO_REF:0000024, GO:0009986=PMID:15528193, GO:0051346=GO_REF:0000024, GO:0072593=GO_REF:0000019, GO:0045980=GO_REF:0000002, GO:0042030=PMID:12110673, GO:0042981=GO_REF:0000019, GO:0006091=PMID:10664857, GO:0001525=PMID:15528193, GO:0042803=GO_REF:0000024, GO:0006783=PMID:23135403, GO:0005753=PMID:12110673, GO:0005739=GO_REF:0000052, GO:0001937=PMID:15528193, GO:0043532=PMID:15528193, GO:0051289=GO_REF:0000024, GO:0030218=PMID:23135403, GO:0051117=PMID:15528193, GO:0051260=GO_REF:0000024} Q9UII2 ATPase inhibitor, mitochondrial protein 20101115 {GO:0004857=TAS, GO:0005516=ISS, GO:0009986=IDA, GO:0051346=ISS, GO:0072593=IEA, GO:0045980=IEA, GO:0042030=IDA, GO:0042981=IEA, GO:0006091=TAS, GO:0001525=TAS, GO:0042803=ISS, GO:0006783=IMP, GO:0005753=IDA, GO:0005739=IDA, GO:0001937=IDA, GO:0043532=IDA, GO:0051289=ISS, GO:0030218=IMP, GO:0051117=IDA, GO:0051260=ISS} angiogenesis, erythrocyte differentiation, generation of precursor metabolites and energy, heme biosynthetic process, negative regulation of endothelial cell proliferation, negative regulation of hydrolase activity, negative regulation of nucleotide metabolic process, protein homooligomerization, protein homotetramerization, reactive oxygen species metabolic process, regulation of apoptotic process cell surface, mitochondrial proton-transporting ATP synthase complex, mitochondrion ATPase binding, ATPase inhibitor activity, angiostatin binding, calmodulin binding, enzyme inhibitor activity, protein homodimerization activity Human ATR BHF-UCL UniProtKB {GO:0005515=PMID:20810650, GO:0032407=PMID:16713580, GO:0032405=PMID:16713580, GO:0071480=PMID:9925639, GO:0034644=PMID:9925639, GO:0046777=PMID:9733515, GO:0018105=PMID:9733515, GO:0016301=GO_REF:0000038, GO:0016773=GO_REF:0000002, GO:0001741=GO_REF:0000019, GO:0005694=GO_REF:0000024, GO:0043393=GO_REF:0000019, GO:0007275=PMID:9590286, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0006974=PMID:15538388, GO:0006260=Reactome:REACT_6769, GO:0007049=PMID:9590286, GO:0004672=PMID:14657349, GO:0006281=Reactome:REACT_216, GO:0004674=PMID:9733515, GO:0016605=GO_REF:0000039, GO:0043517=PMID:9925639, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_18335, GO:0008156=PMID:14657349, GO:0000077=PMID:14657349, GO:0090399=PMID:15149599} Q13535 Serine/threonine-protein kinase ATR protein 20110209 {GO:0005515=IPI, GO:0032407=IDA, GO:0032405=IDA, GO:0071480=IDA, GO:0034644=IMP, GO:0046777=IDA, GO:0018105=IDA, GO:0016301=IEA, GO:0016773=IEA, GO:0001741=IEA, GO:0005694=ISS, GO:0043393=IEA, GO:0007275=TAS, GO:0003677=IEA, GO:0005524=IEA, GO:0006974=TAS, GO:0006260=TAS, GO:0007049=TAS, GO:0004672=IDA, GO:0006281=TAS, GO:0004674=IDA, GO:0016605=IEA, GO:0043517=IMP, GO:0000075=TAS, GO:0005654=TAS, GO:0008156=IMP, GO:0000077=IDA, GO:0090399=IMP} DNA damage checkpoint, DNA repair, DNA replication, cell cycle, cell cycle checkpoint, cellular response to UV, cellular response to gamma radiation, multicellular organismal development, negative regulation of DNA replication, peptidyl-serine phosphorylation, positive regulation of DNA damage response, signal transduction by p53 class mediator, protein autophosphorylation, regulation of protein binding, replicative senescence, response to DNA damage stimulus PML body, XY body, chromosome, nucleoplasm ATP binding, DNA binding, MutLalpha complex binding, MutSalpha complex binding, kinase activity, phosphotransferase activity, alcohol group as acceptor, protein binding, protein kinase activity, protein serine/threonine kinase activity Human ATRIP Reactome UniProtKB {GO:0006260=Reactome:REACT_6769, GO:0005515=PMID:14657349, GO:0006281=GO_REF:0000037, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_6939, GO:0000077=PMID:14657349} Q8WXE1 ATR-interacting protein protein 20130213 {GO:0006260=TAS, GO:0005515=IPI, GO:0006281=IEA, GO:0000075=TAS, GO:0005654=TAS, GO:0000077=TAS} DNA damage checkpoint, DNA repair, DNA replication, cell cycle checkpoint nucleoplasm protein binding Human ATRN PINC UniProtKB {GO:0005737=GO_REF:0000019, GO:0006954=GO_REF:0000037, GO:0005886=PMID:9736737, GO:0005887=PMID:10086356, GO:0040014=GO_REF:0000019, GO:0030246=GO_REF:0000002, GO:0004872=GO_REF:0000019, GO:0005615=PMID:17261078, GO:0006979=GO_REF:0000019} O75882 Attractin protein 20030904 {GO:0005737=IEA, GO:0006954=IEA, GO:0005886=NAS, GO:0005887=TAS, GO:0040014=IEA, GO:0030246=IEA, GO:0004872=IEA, GO:0005615=IDA, GO:0006979=IEA} inflammatory response, regulation of multicellular organism growth, response to oxidative stress cytoplasm, extracellular space, integral to plasma membrane, plasma membrane carbohydrate binding, receptor activity Human ATRNL1 ENSEMBL UniProtKB {GO:0007186=GO_REF:0000019, GO:0030246=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q5VV63 Attractin-like protein 1 protein 20130413 {GO:0007186=IEA, GO:0030246=IEA, GO:0016021=IEA} G-protein coupled receptor signaling pathway integral to membrane carbohydrate binding Human Ensembl:ENSMUSP00000076514 ATRX GOC UniProtKB {GO:0005515=PMID:12953102, GO:0006355=PMID:7697714, GO:0070087=PMID:15882967, GO:0004386=PMID:7874112, GO:0005634=PMID:7874112, GO:0006310=PMID:7697714, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0003678=PMID:7697714, GO:0006306=PMID:10742099, GO:0005720=PMID:10570185, GO:0006281=GO_REF:0000037, GO:0003682=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0032508=PMID:7697714, GO:0030900=GO_REF:0000019} P46100 Transcriptional regulator ATRX protein 20130413 {GO:0005515=IPI, GO:0006355=TAS, GO:0070087=IPI, GO:0004386=TAS, GO:0005634=TAS, GO:0006310=TAS, GO:0003677=IEA, GO:0005524=IEA, GO:0003678=TAS, GO:0006306=TAS, GO:0005720=TAS, GO:0006281=IEA, GO:0003682=IEA, GO:0008270=IEA, GO:0032508=TAS, GO:0030900=IEA} DNA duplex unwinding, DNA methylation, DNA recombination, DNA repair, forebrain development, regulation of transcription, DNA-dependent nuclear heterochromatin, nucleus ATP binding, DNA binding, DNA helicase activity, chromatin binding, chromo shadow domain binding, helicase activity, protein binding, zinc ion binding Human ATXN1 HPA UniProtKB {GO:0005515=PMID:23275563, GO:0008344=GO_REF:0000019, GO:0008219=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0043621=PMID:9097953, GO:0016363=PMID:9353120, GO:0043231=GO_REF:0000052, GO:0042802=PMID:16713569, GO:0008266=PMID:11136710, GO:0005737=GO_REF:0000052, GO:0045944=GO_REF:0000019, GO:0042272=PMID:15615787, GO:0051168=PMID:15615787, GO:0006396=PMID:15615787, GO:0060079=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0008022=PMID:15016912, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0042326=GO_REF:0000019, GO:0034046=PMID:11136710, GO:0043569=GO_REF:0000019, GO:0008542=GO_REF:0000019, GO:0005654=PMID:12757932, GO:0045892=PMID:15016912, GO:0042405=PMID:15615787} P54253 Ataxin-1 protein 20080818 {GO:0005515=IPI, GO:0008344=IEA, GO:0008219=IEA, GO:0005634=IDA, GO:0043621=IDA, GO:0016363=IDA, GO:0043231=IDA, GO:0042802=IPI, GO:0008266=IDA, GO:0005737=IDA, GO:0045944=IEA, GO:0042272=IDA, GO:0051168=IDA, GO:0006396=NAS, GO:0060079=IEA, GO:0005730=IDA, GO:0008022=IPI, GO:0003677=IEA, GO:0006351=IEA, GO:0042326=IEA, GO:0034046=IDA, GO:0043569=IEA, GO:0008542=IEA, GO:0005654=IDA, GO:0045892=IDA, GO:0042405=IDA} RNA processing, adult locomotory behavior, cell death, negative regulation of insulin-like growth factor receptor signaling pathway, negative regulation of phosphorylation, negative regulation of transcription, DNA-dependent, nuclear export, positive regulation of transcription from RNA polymerase II promoter, regulation of excitatory postsynaptic membrane potential, transcription, DNA-dependent, visual learning cytoplasm, intracellular membrane-bounded organelle, nuclear RNA export factor complex, nuclear inclusion body, nuclear matrix, nucleolus, nucleoplasm, nucleus DNA binding, identical protein binding, poly(G) RNA binding, poly(U) RNA binding, protein C-terminus binding, protein binding, protein self-association Human ATXN10 LIFEdb UniProtKB {GO:0005515=PMID:21565611, GO:0008219=GO_REF:0000037, GO:0048471=PMID:16498633, GO:0005737=GO_REF:0000054, GO:0043025=PMID:15201271, GO:0031175=PMID:16498633, GO:0030425=PMID:15201271, GO:0007399=PMID:16385455, GO:0042802=GO_REF:0000019, GO:0005829=GO_REF:0000019} Q9UBB4 Ataxin-10 protein 20100607 {GO:0005515=IPI, GO:0008219=IEA, GO:0048471=IDA, GO:0005737=IDA, GO:0043025=IDA, GO:0031175=IDA, GO:0030425=IDA, GO:0007399=IMP, GO:0042802=IEA, GO:0005829=IEA} cell death, nervous system development, neuron projection development cytoplasm, cytosol, dendrite, neuronal cell body, perinuclear region of cytoplasm identical protein binding, protein binding Human ATXN1L UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0003723=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0030425=GO_REF:0000039, GO:0006351=GO_REF:0000037} P0C7T5 Ataxin-1-like protein 20130413 {GO:0006355=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0030425=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent dendrite, nucleus DNA binding, RNA binding Human UniProtKB-SubCell:SL-0283 ATXN2 HPA UniProtKB {GO:0005515=PMID:23209657, GO:0008219=GO_REF:0000037, GO:0005154=PMID:18602463, GO:0048471=PMID:17097639, GO:0005794=PMID:12812977, GO:0033962=PMID:17392519, GO:0016070=PMID:15663938, GO:0010494=PMID:17392519, GO:0003723=PMID:10814712, GO:0005730=GO_REF:0000052, GO:0050658=PMID:10814712, GO:0005634=GO_REF:0000052, GO:0008022=PMID:15663938, GO:0006417=PMID:16835262, GO:0048872=GO_REF:0000019, GO:0050905=GO_REF:0000019, GO:0034063=PMID:17392519, GO:0005737=GO_REF:0000052, GO:0040015=GO_REF:0000019, GO:0021702=GO_REF:0000019, GO:0030529=PMID:16835262, GO:0048812=GO_REF:0000019, GO:0005844=PMID:16835262, GO:0002091=PMID:18602463} Q99700 Ataxin-2 protein 20100326 {GO:0005515=IPI, GO:0008219=IEA, GO:0005154=IPI, GO:0048471=IDA, GO:0005794=IDA, GO:0033962=IMP, GO:0016070=NAS, GO:0010494=IDA, GO:0003723=NAS, GO:0005730=IDA, GO:0050658=NAS, GO:0005634=IDA, GO:0008022=IPI, GO:0006417=NAS, GO:0048872=IEA, GO:0050905=IEA, GO:0034063=IMP, GO:0005737=IDA, GO:0040015=IEA, GO:0021702=IEA, GO:0030529=IDA, GO:0048812=IEA, GO:0005844=IDA, GO:0002091=IMP} RNA metabolic process, RNA transport, cell death, cerebellar Purkinje cell differentiation, cytoplasmic mRNA processing body assembly, homeostasis of number of cells, negative regulation of multicellular organism growth, negative regulation of receptor internalization, neuromuscular process, neuron projection morphogenesis, regulation of translation, stress granule assembly Golgi apparatus, cytoplasm, cytoplasmic stress granule, nucleolus, nucleus, perinuclear region of cytoplasm, polysome, ribonucleoprotein complex RNA binding, epidermal growth factor receptor binding, protein C-terminus binding, protein binding Human ATXN2L IntAct UniProtKB {GO:0005515=PMID:23209657, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0034063=PMID:23209657, GO:0016020=PMID:11784712, GO:0016607=PMID:23209657, GO:0010494=PMID:23209657, GO:0010603=PMID:23209657} Q8WWM7 Ataxin-2-like protein protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0003674=ND, GO:0034063=IMP, GO:0016020=IDA, GO:0016607=IDA, GO:0010494=IDA, GO:0010603=IDA} biological_process, regulation of cytoplasmic mRNA processing body assembly, stress granule assembly cytoplasmic stress granule, membrane, nuclear speck molecular_function, protein binding Human UniProtKB:Q13283 ATXN3 IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0008219=GO_REF:0000037, GO:0030036=PMID:20637808, GO:0004843=GO_REF:0000024, GO:0045104=PMID:20637808, GO:0010810=PMID:20637808, GO:0007268=PMID:7655453, GO:0016363=GO_REF:0000039, GO:0034605=GO_REF:0000019, GO:0005737=PMID:9124802, GO:0005759=GO_REF:0000019, GO:0035520=GO_REF:0000024, GO:0008242=GO_REF:0000002, GO:0035640=GO_REF:0000019, GO:0031625=GO_REF:0000024, GO:0071218=GO_REF:0000024, GO:0070932=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0031966=GO_REF:0000019, GO:0000226=PMID:20637808, GO:0006351=GO_REF:0000037, GO:0007399=PMID:9124802, GO:0005654=PMID:9580663, GO:0006515=GO_REF:0000024, GO:0043161=GO_REF:0000024, GO:0004221=GO_REF:0000024, GO:0006289=PMID:10915768, GO:0001012=GO_REF:0000019, GO:0042405=GO_REF:0000019} P54252 Ataxin-3 protein 20130415 {GO:0005515=IPI, GO:0008219=IEA, GO:0030036=IMP, GO:0004843=ISS, GO:0045104=IMP, GO:0010810=IMP, GO:0007268=TAS, GO:0016363=IEA, GO:0034605=IEA, GO:0005737=TAS, GO:0005759=IEA, GO:0035520=ISS, GO:0008242=IEA, GO:0035640=IEA, GO:0031625=ISS, GO:0071218=ISS, GO:0070932=IEA, GO:0006355=IEA, GO:0031966=IEA, GO:0000226=IMP, GO:0006351=IEA, GO:0007399=TAS, GO:0005654=TAS, GO:0006515=ISS, GO:0043161=ISS, GO:0004221=ISS, GO:0006289=TAS, GO:0001012=IEA, GO:0042405=IEA} actin cytoskeleton organization, cell death, cellular response to heat, cellular response to misfolded protein, exploration behavior, histone H3 deacetylation, intermediate filament cytoskeleton organization, microtubule cytoskeleton organization, misfolded or incompletely synthesized protein catabolic process, monoubiquitinated protein deubiquitination, nervous system development, nucleotide-excision repair, proteasomal ubiquitin-dependent protein catabolic process, regulation of cell-substrate adhesion, regulation of transcription, DNA-dependent, synaptic transmission, transcription, DNA-dependent cytoplasm, mitochondrial matrix, mitochondrial membrane, nuclear inclusion body, nuclear matrix, nucleoplasm RNA polymerase II regulatory region DNA binding, omega peptidase activity, protein binding, ubiquitin protein ligase binding, ubiquitin thiolesterase activity, ubiquitin-specific protease activity Human UniProtKB:Q9BSU1 ATXN3L UniProtKB UniProtKB {GO:0016579=PMID:21118805, GO:0006355=GO_REF:0000037, GO:0004843=PMID:21118805, GO:0006508=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008242=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q9H3M9 Putative ataxin-3-like protein protein 20110218 {GO:0016579=IDA, GO:0006355=IEA, GO:0004843=IDA, GO:0006508=IEA, GO:0005634=IEA, GO:0008242=IEA, GO:0006351=IEA} protein deubiquitination, proteolysis, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus omega peptidase activity, ubiquitin-specific protease activity Human ATXN7 HPA UniProtKB {GO:0005515=PMID:21078624, GO:0008219=GO_REF:0000037, GO:0016578=PMID:18206972, GO:0006997=PMID:10441328, GO:0005730=GO_REF:0000052, GO:0000226=PMID:22100762, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037, GO:0016363=GO_REF:0000039, GO:0042326=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0043569=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0015630=PMID:22100762, GO:0007601=PMID:9288099} O15265 Ataxin-7 protein 20101115 {GO:0005515=IPI, GO:0008219=IEA, GO:0016578=IDA, GO:0006997=TAS, GO:0005730=IDA, GO:0000226=IMP, GO:0005634=IDA, GO:0006351=IEA, GO:0016363=IEA, GO:0042326=IEA, GO:0005737=IDA, GO:0043569=IEA, GO:0003682=IEA, GO:0045944=IEA, GO:0015630=IDA, GO:0007601=TAS} cell death, histone deubiquitination, microtubule cytoskeleton organization, negative regulation of insulin-like growth factor receptor signaling pathway, negative regulation of phosphorylation, nucleus organization, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent, visual perception cytoplasm, microtubule cytoskeleton, nuclear matrix, nucleolus, nucleus chromatin binding, protein binding Human ATXN7L1 null null {} null null null null {} null null null ATXN7L2 null null {} null null null null {} null null null ATXN7L3 UniProtKB UniProtKB {GO:0005515=PMID:18206972, GO:0016578=PMID:18206972, GO:0030374=PMID:18206972, GO:0000124=PMID:18206972, GO:0003713=PMID:18206972, GO:0045893=PMID:18206972, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q14CW9 Ataxin-7-like protein 3 protein 20090427 {GO:0005515=IPI, GO:0016578=IDA, GO:0030374=IDA, GO:0000124=IDA, GO:0003713=IDA, GO:0045893=IDA, GO:0046872=IEA, GO:0006351=IEA} histone deubiquitination, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent SAGA complex ligand-dependent nuclear receptor transcription coactivator activity, metal ion binding, protein binding, transcription coactivator activity Human ATXN7L3B null null {} null null null null {} null null null AUH Reactome UniProtKB {GO:0005739=GO_REF:0000024, GO:0034641=Reactome:REACT_13, GO:0005759=Reactome:REACT_1157, GO:0004490=Reactome:REACT_1157, GO:0009083=Reactome:REACT_197, GO:0044281=Reactome:REACT_111217, GO:0003730=PMID:7892223, GO:0004300=PMID:7892223, GO:0006402=PMID:7892223, GO:0003824=GO_REF:0000002, GO:0006552=GO_REF:0000041} Q13825 Methylglutaconyl-CoA hydratase, mitochondrial protein 20100211 {GO:0005739=ISS, GO:0034641=TAS, GO:0005759=TAS, GO:0004490=EXP, GO:0009083=TAS, GO:0044281=TAS, GO:0003730=IDA, GO:0004300=IDA, GO:0006402=IDA, GO:0003824=IEA, GO:0006552=IEA} branched-chain amino acid catabolic process, cellular nitrogen compound metabolic process, leucine catabolic process, mRNA catabolic process, small molecule metabolic process mitochondrial matrix, mitochondrion catalytic activity, enoyl-CoA hydratase activity, mRNA 3'-UTR binding, methylglutaconyl-CoA hydratase activity Human AUP1 HPA UniProtKB {GO:0005783=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005789=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0016021=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q9Y679 Ancient ubiquitous protein 1 protein 20110516 {GO:0005783=IDA, GO:0005730=IDA, GO:0005789=IEA, GO:0005634=IDA, GO:0016021=IEA, GO:0043231=IDA} endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle, nucleolus, nucleus Human AURKA ENSEMBL UniProtKB {GO:0005515=PMID:19801554, GO:0048471=PMID:20531406, GO:0005634=PMID:20531406, GO:0031145=Reactome:REACT_6828, GO:0005829=Reactome:REACT_6974, GO:0046777=PMID:19774610, GO:0031647=PMID:15987997, GO:0005876=PMID:19801554, GO:0007051=PMID:15504738, GO:0031625=GO_REF:0000019, GO:0005813=PMID:21399614, GO:0019901=PMID:18615013, GO:0048015=PMID:15504738, GO:0005819=PMID:19774610, GO:0030496=PMID:19774610, GO:0045840=PMID:19774610, GO:0046605=PMID:19774610, GO:0005524=GO_REF:0000002, GO:0007049=PMID:15504738, GO:0007067=GO_REF:0000037, GO:0004672=PMID:19801554, GO:0004674=GO_REF:0000002, GO:0030030=GO_REF:0000037, GO:0004712=PMID:19774610, GO:0006468=PMID:9153231, GO:0031616=PMID:19801554, GO:0000278=GO_REF:0000019, GO:0051301=GO_REF:0000037} Q5QPD4 Aurora kinase A protein 20130413 {GO:0005515=IPI, GO:0048471=IDA, GO:0005634=IDA, GO:0031145=TAS, GO:0005829=TAS, GO:0046777=TAS, GO:0031647=IMP, GO:0005876=IDA, GO:0007051=NAS, GO:0031625=IEA, GO:0005813=IDA, GO:0019901=IPI, GO:0048015=NAS, GO:0005819=TAS, GO:0030496=TAS, GO:0045840=TAS, GO:0046605=TAS, GO:0005524=IEA, GO:0007049=NAS, GO:0007067=IEA, GO:0004672=IDA, GO:0004674=IEA, GO:0030030=IEA, GO:0004712=TAS, GO:0006468=TAS, GO:0031616=IDA, GO:0000278=IEA, GO:0051301=IEA} anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle, cell division, cell projection organization, mitosis, mitotic cell cycle, phosphatidylinositol-mediated signaling, positive regulation of mitosis, protein autophosphorylation, protein phosphorylation, regulation of centrosome cycle, regulation of protein stability, spindle organization centrosome, cytosol, midbody, nucleus, perinuclear region of cytoplasm, spindle, spindle microtubule, spindle pole centrosome ATP binding, protein binding, protein kinase activity, protein kinase binding, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity, ubiquitin protein ligase binding Human Ensembl:ENSMUSP00000028997 AURKAIP1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005515=PMID:12244051, GO:0045839=PMID:12244051, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0045862=PMID:12244051, GO:0043231=GO_REF:0000052} Q9NWT8 Aurora kinase A-interacting protein protein 20101115 {GO:0005739=IDA, GO:0005515=IPI, GO:0045839=NAS, GO:0005730=IDA, GO:0005634=IDA, GO:0045862=IDA, GO:0043231=IDA} negative regulation of mitosis, positive regulation of proteolysis intracellular membrane-bounded organelle, mitochondrion, nucleolus, nucleus protein binding Human AURKB BHF-UCL UniProtKB {GO:0005515=PMID:22939624, GO:0051256=PMID:16103226, GO:0000236=Reactome:REACT_682, GO:0008283=GO_REF:0000019, GO:0034501=PMID:19468067, GO:0005634=PMID:20959462, GO:0031145=Reactome:REACT_6828, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_150414, GO:0036089=PMID:16103226, GO:0000910=GO_REF:0000019, GO:0034644=PMID:20959462, GO:0046777=PMID:19774610, GO:0002903=PMID:20959462, GO:0000087=Reactome:REACT_910, GO:0000780=PMID:18195732, GO:0010369=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0005819=PMID:19774610, GO:0051983=PMID:19774610, GO:0030496=PMID:19774610, GO:0016570=PMID:19774610, GO:0000122=PMID:20959462, GO:0005524=GO_REF:0000037, GO:0032133=PMID:19774610, GO:0007049=GO_REF:0000019, GO:0004672=GO_REF:0000019, GO:0004674=GO_REF:0000037, GO:0000779=PMID:19465021, GO:0004712=PMID:19774610, GO:0000278=Reactome:REACT_152, GO:0008608=PMID:19774610, GO:0000090=Reactome:REACT_1275} Q96GD4 Aurora kinase B protein 20100107 {GO:0005515=IPI, GO:0051256=IMP, GO:0000236=TAS, GO:0008283=IEA, GO:0034501=IMP, GO:0005634=IDA, GO:0031145=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0036089=IDA, GO:0000910=IEA, GO:0034644=IDA, GO:0046777=TAS, GO:0002903=IDA, GO:0000087=TAS, GO:0000780=IDA, GO:0010369=IEA, GO:0007568=IEA, GO:0005819=TAS, GO:0051983=TAS, GO:0030496=TAS, GO:0016570=TAS, GO:0000122=IDA, GO:0005524=IEA, GO:0032133=TAS, GO:0007049=IEA, GO:0004672=IEA, GO:0004674=IEA, GO:0000779=IDA, GO:0004712=TAS, GO:0000278=TAS, GO:0008608=TAS, GO:0000090=TAS} M phase of mitotic cell cycle, aging, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, attachment of spindle microtubules to kinetochore, cell cycle, cell proliferation, cellular response to UV, cleavage furrow formation, cytokinesis, histone modification, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, negative regulation of B cell apoptotic process, negative regulation of transcription from RNA polymerase II promoter, protein autophosphorylation, protein localization to kinetochore, regulation of chromosome segregation, spindle midzone assembly involved in mitosis chromocenter, chromosome passenger complex, condensed chromosome, centromeric region, condensed nuclear chromosome, centromeric region, cytosol, midbody, nucleus, spindle ATP binding, metal ion binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity Human AURKC PINC UniProtKB {GO:0051256=PMID:19774610, GO:0000793=PMID:15670791, GO:0005819=PMID:19774610, GO:0016570=PMID:19774610, GO:0030496=PMID:19774610, GO:0005634=GO_REF:0000039, GO:0051233=PMID:15670791, GO:0005524=GO_REF:0000037, GO:0000910=PMID:10066797, GO:0032133=PMID:19774610, GO:0005737=GO_REF:0000037, GO:0004672=PMID:15670791, GO:0007126=GO_REF:0000037, GO:0004674=GO_REF:0000037, GO:0004712=PMID:19774610, GO:0006468=PMID:15670791, GO:0008608=PMID:19774610, GO:0000775=GO_REF:0000039} Q9UQB9 Aurora kinase C protein 20050308 {GO:0051256=TAS, GO:0000793=IDA, GO:0005819=TAS, GO:0016570=TAS, GO:0030496=TAS, GO:0005634=IEA, GO:0051233=IDA, GO:0005524=IEA, GO:0000910=TAS, GO:0032133=TAS, GO:0005737=IEA, GO:0004672=IDA, GO:0007126=IEA, GO:0004674=IEA, GO:0004712=TAS, GO:0006468=IDA, GO:0008608=TAS, GO:0000775=IEA} attachment of spindle microtubules to kinetochore, cytokinesis, histone modification, meiosis, protein phosphorylation, spindle midzone assembly involved in mitosis chromosome passenger complex, chromosome, centromeric region, condensed chromosome, cytoplasm, midbody, nucleus, spindle, spindle midzone ATP binding, protein kinase activity, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity Human AUTS2 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q8WXX7 Autism susceptibility gene 2 protein protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human AVEN UniProtKB UniProtKB {GO:0005622=PMID:10949025, GO:0005515=PMID:10949025, GO:0043066=PMID:10949025, GO:0016020=PMID:10949025, GO:0006915=GO_REF:0000037, GO:0012505=GO_REF:0000039} Q9NQS1 Cell death regulator Aven protein 20040128 {GO:0005622=IDA, GO:0005515=IPI, GO:0043066=IDA, GO:0016020=IDA, GO:0006915=IEA, GO:0012505=IEA} apoptotic process, negative regulation of apoptotic process endomembrane system, intracellular, membrane protein binding Human AVIL PINC UniProtKB {GO:0043005=GO_REF:0000024, GO:0030424=GO_REF:0000039, GO:0005737=GO_REF:0000037, GO:0060271=PMID:20393563, GO:0007010=GO_REF:0000002, GO:0010976=GO_REF:0000024, GO:0006950=GO_REF:0000019, GO:0003779=GO_REF:0000024, GO:0042995=GO_REF:0000024, GO:0015629=PMID:9664034, GO:0007399=PMID:9664034, GO:0051693=GO_REF:0000037} O75366 Advillin protein 20030904 {GO:0043005=ISS, GO:0030424=IEA, GO:0005737=IEA, GO:0060271=IMP, GO:0007010=IEA, GO:0010976=ISS, GO:0006950=IEA, GO:0003779=ISS, GO:0042995=ISS, GO:0015629=TAS, GO:0007399=TAS, GO:0051693=IEA} actin filament capping, cilium morphogenesis, cytoskeleton organization, nervous system development, positive regulation of neuron projection development, response to stress actin cytoskeleton, axon, cell projection, cytoplasm, neuron projection actin binding Human AVL9 UniProtKB UniProtKB {GO:0016477=PMID:22595670, GO:0016021=GO_REF:0000037, GO:0055037=PMID:22595670} Q8NBF6 Late secretory pathway protein AVL9 homolog protein 20121001 {GO:0016477=IDA, GO:0016021=IEA, GO:0055037=IDA} cell migration integral to membrane, recycling endosome Human AVP GOC UniProtKB {GO:0030307=GO_REF:0000019, GO:0006091=PMID:1740104, GO:0051970=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0003084=GO_REF:0000019, GO:0006833=Reactome:REACT_24023, GO:0070371=PMID:18402937, GO:0005184=PMID:1740104, GO:0005185=GO_REF:0000002, GO:0043027=PMID:18402937, GO:0031394=GO_REF:0000019, GO:0042538=GO_REF:0000019, GO:0043084=GO_REF:0000019, GO:0002125=GO_REF:0000019, GO:0035176=GO_REF:0000019, GO:0035813=GO_REF:0000019, GO:0007621=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0030819=GO_REF:0000019, GO:0007267=PMID:1740104, GO:0031894=PMID:18402937, GO:0043252=Reactome:REACT_23988, GO:0031895=GO_REF:0000019, GO:0007204=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0005829=Reactome:REACT_23822, GO:0014049=GO_REF:0000019, GO:0033138=PMID:18402937, GO:0045907=GO_REF:0000019, GO:0090201=PMID:18402937, GO:0042310=GO_REF:0000037, GO:0007626=GO_REF:0000019, GO:0007625=GO_REF:0000019, GO:0004871=PMID:18402937, GO:0030141=GO_REF:0000019, GO:0043154=PMID:18402937, GO:0042711=GO_REF:0000019, GO:0043066=PMID:18402937, GO:0005102=PMID:1740104, GO:0032849=GO_REF:0000019, GO:0005576=Reactome:REACT_23926, GO:0055085=Reactome:REACT_19118, GO:0070528=PMID:18402937, GO:0010628=PMID:18538351, GO:0007165=PMID:18402937, GO:0004672=PMID:18402937, GO:0050891=GO_REF:0000019, GO:0006468=PMID:18402937, GO:0035094=GO_REF:0000019} P01185 Vasopressin-neurophysin 2-copeptin protein 20130413 {GO:0030307=IEA, GO:0006091=TAS, GO:0051970=IEA, GO:0005615=IEA, GO:0003084=IEA, GO:0006833=TAS, GO:0070371=IDA, GO:0005184=TAS, GO:0005185=IEA, GO:0043027=IDA, GO:0031394=IEA, GO:0042538=IEA, GO:0043084=IEA, GO:0002125=IEA, GO:0035176=IEA, GO:0035813=IEA, GO:0007621=IEA, GO:0008284=IEA, GO:0045471=IEA, GO:0030819=IEA, GO:0007267=TAS, GO:0031894=IPI, GO:0043252=TAS, GO:0031895=IEA, GO:0007204=IEA, GO:0030425=IEA, GO:0005829=TAS, GO:0014049=IEA, GO:0033138=IDA, GO:0045907=IEA, GO:0090201=IDA, GO:0042310=IEA, GO:0007626=IEA, GO:0007625=IEA, GO:0004871=IDA, GO:0030141=IEA, GO:0043154=IDA, GO:0042711=IEA, GO:0043066=IDA, GO:0005102=TAS, GO:0032849=IEA, GO:0005576=TAS, GO:0055085=TAS, GO:0070528=IDA, GO:0010628=IDA, GO:0007165=IDA, GO:0004672=IDA, GO:0050891=IEA, GO:0006468=IDA, GO:0035094=IEA} ERK1 and ERK2 cascade, cell-cell signaling, elevation of cytosolic calcium ion concentration, generation of precursor metabolites and energy, grooming behavior, hyperosmotic salinity response, locomotory behavior, maternal aggressive behavior, maternal behavior, multicellular organismal water homeostasis, negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of female receptivity, negative regulation of release of cytochrome c from mitochondria, negative regulation of transmission of nerve impulse, penile erection, positive regulation of cAMP biosynthetic process, positive regulation of cell growth, positive regulation of cell proliferation, positive regulation of cellular pH reduction, positive regulation of gene expression, positive regulation of glutamate secretion, positive regulation of peptidyl-serine phosphorylation, positive regulation of prostaglandin biosynthetic process, positive regulation of systemic arterial blood pressure, positive regulation of vasoconstriction, protein kinase C signaling cascade, protein phosphorylation, regulation of renal sodium excretion, response to ethanol, response to nicotine, signal transduction, social behavior, sodium-independent organic anion transport, transmembrane transport, vasoconstriction, water transport cytosol, dendrite, extracellular region, extracellular space, secretory granule V1A vasopressin receptor binding, V1B vasopressin receptor binding, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, neurohypophyseal hormone activity, neuropeptide hormone activity, protein kinase activity, receptor binding, signal transducer activity Human AVPI1 ENSEMBL UniProtKB {GO:0000187=GO_REF:0000019, GO:0007049=GO_REF:0000037} Q5T686 Arginine vasopressin-induced protein 1 protein 20130413 {GO:0000187=IEA, GO:0007049=IEA} activation of MAPK activity, cell cycle Human Ensembl:ENSMUSP00000018965 AVPR1A Reactome UniProtKB {GO:0005515=PMID:18402937, GO:0008284=GO_REF:0000019, GO:0019722=GO_REF:0000019, GO:0005886=Reactome:REACT_22436, GO:0030307=GO_REF:0000019, GO:0008015=PMID:8106369, GO:0031894=GO_REF:0000019, GO:0006091=PMID:8106369, GO:0007202=PMID:8106369, GO:0051970=GO_REF:0000019, GO:0007204=GO_REF:0000019, GO:0021537=GO_REF:0000019, GO:0001992=GO_REF:0000019, GO:0014049=GO_REF:0000019, GO:0003084=GO_REF:0000019, GO:0045907=GO_REF:0000019, GO:0005000=GO_REF:0000002, GO:0005080=PMID:10858434, GO:0007625=GO_REF:0000019, GO:0051412=GO_REF:0000019, GO:0042631=GO_REF:0000019, GO:0042711=GO_REF:0000019, GO:0014902=GO_REF:0000019, GO:0031394=GO_REF:0000019, GO:0032849=GO_REF:0000019, GO:0043084=GO_REF:0000019, GO:0031410=GO_REF:0000019, GO:0042713=GO_REF:0000019, GO:0002125=GO_REF:0000019, GO:0007186=PMID:10858434, GO:0005887=PMID:8838314, GO:0035176=GO_REF:0000019, GO:0035815=GO_REF:0000019, GO:0007621=GO_REF:0000019, GO:0010460=GO_REF:0000019, GO:0016021=GO_REF:0000002, GO:0017046=GO_REF:0000019, GO:0005768=PMID:10858434} P37288 Vasopressin V1a receptor protein 20081212 {GO:0005515=IPI, GO:0008284=IEA, GO:0019722=IEA, GO:0005886=TAS, GO:0030307=IEA, GO:0008015=TAS, GO:0031894=IEA, GO:0006091=TAS, GO:0007202=TAS, GO:0051970=IEA, GO:0007204=IEA, GO:0021537=IEA, GO:0001992=IEA, GO:0014049=IEA, GO:0003084=IEA, GO:0045907=IEA, GO:0005000=IEA, GO:0005080=TAS, GO:0007625=IEA, GO:0051412=IEA, GO:0042631=IEA, GO:0042711=IEA, GO:0014902=IEA, GO:0031394=IEA, GO:0032849=IEA, GO:0043084=IEA, GO:0031410=IEA, GO:0042713=IEA, GO:0002125=IEA, GO:0007186=TAS, GO:0005887=TAS, GO:0035176=IEA, GO:0035815=IEA, GO:0007621=IEA, GO:0010460=IEA, GO:0016021=IEA, GO:0017046=IEA, GO:0005768=TAS} G-protein coupled receptor signaling pathway, activation of phospholipase C activity, blood circulation, calcium-mediated signaling, cellular response to water deprivation, elevation of cytosolic calcium ion concentration, generation of precursor metabolites and energy, grooming behavior, maternal aggressive behavior, maternal behavior, myotube differentiation, negative regulation of female receptivity, negative regulation of transmission of nerve impulse, penile erection, positive regulation of cell growth, positive regulation of cell proliferation, positive regulation of cellular pH reduction, positive regulation of glutamate secretion, positive regulation of heart rate, positive regulation of prostaglandin biosynthetic process, positive regulation of renal sodium excretion, positive regulation of systemic arterial blood pressure, positive regulation of vasoconstriction, regulation of systemic arterial blood pressure by vasopressin, response to corticosterone stimulus, social behavior, sperm ejaculation, telencephalon development cytoplasmic vesicle, endosome, integral to membrane, integral to plasma membrane, plasma membrane V1A vasopressin receptor binding, peptide hormone binding, protein binding, protein kinase C binding, vasopressin receptor activity Human AVPR1B Reactome UniProtKB {GO:0005886=Reactome:REACT_22436, GO:0007186=PMID:10858434, GO:0005887=PMID:7805841, GO:0005000=GO_REF:0000002, GO:0005080=PMID:10858434, GO:0007202=PMID:7805841, GO:0007204=PMID:7929452, GO:0001992=GO_REF:0000019, GO:0005768=PMID:10858434} P47901 Vasopressin V1b receptor protein 20081212 {GO:0005886=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0005000=IEA, GO:0005080=TAS, GO:0007202=TAS, GO:0007204=TAS, GO:0001992=IEA, GO:0005768=TAS} G-protein coupled receptor signaling pathway, activation of phospholipase C activity, elevation of cytosolic calcium ion concentration, regulation of systemic arterial blood pressure by vasopressin endosome, integral to plasma membrane, plasma membrane protein kinase C binding, vasopressin receptor activity Human AVPR2 BHF-UCL UniProtKB {GO:0007588=PMID:1303257, GO:0008284=GO_REF:0000019, GO:0005794=PMID:10880054, GO:0005886=Reactome:REACT_23926, GO:0005783=PMID:10880054, GO:0007249=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0021537=GO_REF:0000019, GO:0007599=PMID:10880054, GO:0010628=GO_REF:0000024, GO:0007190=PMID:9224808, GO:0003084=GO_REF:0000019, GO:0005887=PMID:1303257, GO:0005000=PMID:8882880, GO:0031398=PMID:19372219, GO:0035814=GO_REF:0000019, GO:0007188=PMID:10880054, GO:0006833=Reactome:REACT_24023, GO:0016021=PMID:8882880, GO:0035811=GO_REF:0000019, GO:0032609=GO_REF:0000019, GO:0034097=GO_REF:0000019, GO:0005768=PMID:10858434} P30518 Vasopressin V2 receptor protein 20120316 {GO:0007588=TAS, GO:0008284=IEA, GO:0005794=TAS, GO:0005886=TAS, GO:0005783=TAS, GO:0007249=IEA, GO:0055085=TAS, GO:0021537=IEA, GO:0007599=TAS, GO:0010628=ISS, GO:0007190=TAS, GO:0003084=IEA, GO:0005887=TAS, GO:0005000=TAS, GO:0031398=NAS, GO:0035814=IEA, GO:0007188=TAS, GO:0006833=TAS, GO:0016021=NAS, GO:0035811=IEA, GO:0032609=IEA, GO:0034097=IEA, GO:0005768=TAS} I-kappaB kinase/NF-kappaB cascade, activation of adenylate cyclase activity, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, excretion, hemostasis, interferon-gamma production, negative regulation of renal sodium excretion, negative regulation of urine volume, positive regulation of cell proliferation, positive regulation of gene expression, positive regulation of protein ubiquitination, positive regulation of systemic arterial blood pressure, response to cytokine stimulus, telencephalon development, transmembrane transport, water transport Golgi apparatus, endoplasmic reticulum, endosome, integral to membrane, integral to plasma membrane, plasma membrane vasopressin receptor activity Human AXIN1 GOC UniProtKB {GO:0005515=PMID:10644691, GO:0008219=GO_REF:0000033, GO:0008013=PMID:16890161, GO:0045599=GO_REF:0000033, GO:0007605=GO_REF:0000019, GO:0030877=PMID:16188939, GO:0046330=GO_REF:0000024, GO:0038032=GO_REF:0000002, GO:0046332=PMID:18593713, GO:0031122=GO_REF:0000033, GO:0043621=GO_REF:0000019, GO:0043623=PMID:16601693, GO:0042803=GO_REF:0000024, GO:0042802=GO_REF:0000024, GO:0005622=GO_REF:0000002, GO:0030163=GO_REF:0000019, GO:0021797=GO_REF:0000033, GO:0031398=PMID:18593713, GO:0051443=PMID:16601693, GO:0051260=GO_REF:0000019, GO:0005938=GO_REF:0000033, GO:0031625=PMID:16601693, GO:0000209=GO_REF:0000019, GO:0010800=PMID:18593713, GO:0030910=GO_REF:0000033, GO:0001743=GO_REF:0000033, GO:0019901=GO_REF:0000024, GO:0014069=GO_REF:0000033, GO:0007275=GO_REF:0000002, GO:0001701=GO_REF:0000019, GO:0051248=GO_REF:0000019, GO:0043547=GO_REF:0000033, GO:0060823=GO_REF:0000033, GO:0060272=GO_REF:0000033, GO:0045893=PMID:16601693, GO:0019899=PMID:21478859, GO:0021881=GO_REF:0000033, GO:0070016=GO_REF:0000024, GO:0005881=GO_REF:0000033, GO:0048471=PMID:19038973, GO:0045732=PMID:9601641, GO:0007368=GO_REF:0000033, GO:0005886=PMID:16890161, GO:0030178=PMID:10644691, GO:0032436=GO_REF:0000019, GO:0005634=PMID:12072559, GO:0090244=GO_REF:0000033, GO:0009950=GO_REF:0000033, GO:0035412=GO_REF:0000033, GO:0071944=PMID:19038973, GO:0005829=Reactome:REACT_10134, GO:0032147=PMID:9601641, GO:0002039=PMID:15526030, GO:0033138=PMID:18593713, GO:0005737=PMID:17569865, GO:0071514=GO_REF:0000019, GO:0004871=PMID:9601641, GO:0034244=GO_REF:0000019, GO:0060070=PMID:9601641, GO:0090090=GO_REF:0000033, GO:0030511=GO_REF:0000019, GO:0048048=GO_REF:0000033, GO:0070411=PMID:16601693, GO:0006915=GO_REF:0000037, GO:0070412=GO_REF:0000019, GO:0031410=GO_REF:0000024, GO:0007257=GO_REF:0000033, GO:0008022=GO_REF:0000019, GO:0016328=PMID:12072559, GO:0036342=GO_REF:0000019, GO:0006913=GO_REF:0000019, GO:2000060=GO_REF:0000024, GO:0032947=PMID:9601641, GO:0071407=GO_REF:0000033, GO:0001934=PMID:9601641, GO:0016023=GO_REF:0000033, GO:0055001=GO_REF:0000033, GO:0005096=GO_REF:0000033, GO:0048320=GO_REF:0000033} O15169 Axin-1 protein 20130413 {GO:0005515=IPI, GO:0008219=IBA, GO:0008013=IPI, GO:0045599=IBA, GO:0007605=IEA, GO:0030877=IDA, GO:0046330=ISS, GO:0038032=IEA, GO:0046332=IPI, GO:0031122=IBA, GO:0043621=IEA, GO:0043623=IDA, GO:0042803=ISS, GO:0042802=ISS, GO:0005622=IEA, GO:0030163=IEA, GO:0021797=IBA, GO:0031398=IDA, GO:0051443=IMP, GO:0051260=IEA, GO:0005938=IBA, GO:0031625=IPI, GO:0000209=IEA, GO:0010800=IDA, GO:0030910=IBA, GO:0001743=IBA, GO:0019901=ISS, GO:0014069=IBA, GO:0007275=IEA, GO:0001701=IEA, GO:0051248=IEA, GO:0043547=IBA, GO:0060823=IBA, GO:0060272=IBA, GO:0045893=IMP, GO:0019899=IPI, GO:0021881=IBA, GO:0070016=ISS, GO:0005881=IBA, GO:0048471=IDA, GO:0045732=IDA, GO:0007368=IBA, GO:0005886=IDA, GO:0030178=IDA, GO:0032436=IEA, GO:0005634=IDA, GO:0090244=IBA, GO:0009950=IBA, GO:0035412=IBA, GO:0071944=IDA, GO:0005829=TAS, GO:0032147=IDA, GO:0002039=IDA, GO:0033138=IDA, GO:0005737=IDA, GO:0071514=IEA, GO:0004871=IDA, GO:0034244=IEA, GO:0060070=IC, GO:0090090=IBA, GO:0030511=IEA, GO:0048048=IBA, GO:0070411=IPI, GO:0006915=IEA, GO:0070412=IEA, GO:0031410=ISS, GO:0007257=IBA, GO:0008022=IEA, GO:0016328=IDA, GO:0036342=IEA, GO:0006913=IEA, GO:2000060=ISS, GO:0032947=IDA, GO:0071407=IBA, GO:0001934=IDA, GO:0016023=IBA, GO:0055001=IBA, GO:0005096=IBA, GO:0048320=IBA} Wnt receptor signaling pathway involved in forebrain neuron fate commitment, Wnt receptor signaling pathway involved in somitogenesis, activation of JUN kinase activity, activation of protein kinase activity, apoptotic process, axial mesoderm formation, canonical Wnt receptor signaling pathway, canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation, cell death, cellular protein complex assembly, cellular response to organic cyclic compound, cytoplasmic microtubule organization, determination of left/right symmetry, dorsal/ventral axis specification, embryonic eye morphogenesis, embryonic skeletal joint morphogenesis, forebrain anterior/posterior pattern specification, genetic imprinting, in utero embryonic development, multicellular organismal development, muscle cell development, negative regulation of Wnt receptor signaling pathway, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of fat cell differentiation, negative regulation of protein metabolic process, negative regulation of transcription elongation from RNA polymerase II promoter, nucleocytoplasmic transport, olfactory placode formation, optic placode formation, positive regulation of GTPase activity, positive regulation of JNK cascade, positive regulation of peptidyl-serine phosphorylation, positive regulation of peptidyl-threonine phosphorylation, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of protein catabolic process, positive regulation of protein phosphorylation, positive regulation of protein ubiquitination, positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process, positive regulation of transcription, DNA-dependent, positive regulation of transforming growth factor beta receptor signaling pathway, positive regulation of ubiquitin-protein ligase activity, post-anal tail morphogenesis, protein catabolic process, protein homooligomerization, protein polyubiquitination, regulation of catenin import into nucleus, sensory perception of sound, termination of G-protein coupled receptor signaling pathway beta-catenin destruction complex, cell cortex, cell periphery, cytoplasm, cytoplasmic membrane-bounded vesicle, cytoplasmic microtubule, cytoplasmic vesicle, cytosol, intracellular, lateral plasma membrane, nucleus, perinuclear region of cytoplasm, plasma membrane, postsynaptic density GTPase activator activity, I-SMAD binding, R-SMAD binding, SMAD binding, armadillo repeat domain binding, beta-catenin binding, enzyme binding, identical protein binding, p53 binding, protein C-terminus binding, protein binding, protein complex scaffold, protein homodimerization activity, protein kinase binding, protein self-association, signal transducer activity, ubiquitin protein ligase binding Human PANTHER:PTN000090250 AXIN2 GOC UniProtKB {GO:0008219=GO_REF:0000019, GO:0005881=GO_REF:0000033, GO:0008285=PMID:16247484, GO:0008013=PMID:11017067, GO:0005886=GO_REF:0000033, GO:0008283=GO_REF:0000019, GO:0003413=GO_REF:0000019, GO:0001756=GO_REF:0000019, GO:0030877=PMID:11017067, GO:0010718=PMID:17072303, GO:0038032=GO_REF:0000002, GO:0005634=PMID:12072559, GO:0030282=GO_REF:0000019, GO:0090244=GO_REF:0000033, GO:0035414=PMID:11017067, GO:0009950=GO_REF:0000033, GO:0005622=GO_REF:0000002, GO:2000054=GO_REF:0000019, GO:0005737=PMID:21383061, GO:0045860=GO_REF:0000019, GO:0042476=PMID:15042511, GO:0048255=PMID:17072303, GO:0004871=GO_REF:0000002, GO:0090090=PMID:11017067, GO:0010942=PMID:16247484, GO:0005938=GO_REF:0000033, GO:0031625=PMID:21478859, GO:0070602=PMID:20300119, GO:0005813=PMID:20300119, GO:0019901=GO_REF:0000033, GO:0061181=GO_REF:0000019, GO:0014069=GO_REF:0000033, GO:0070411=GO_REF:0000019, GO:0007275=GO_REF:0000002, GO:0032423=PMID:11017067, GO:0043570=PMID:18755497, GO:0043547=GO_REF:0000033, GO:0043234=GO_REF:0000019, GO:0071407=GO_REF:0000033, GO:0001957=GO_REF:0000033, GO:0045668=GO_REF:0000033, GO:0001934=PMID:20300119, GO:0016023=GO_REF:0000033, GO:0034613=PMID:17072303, GO:0019899=PMID:19759537, GO:0070016=GO_REF:0000033, GO:0005096=GO_REF:0000033} Q9Y2T1 Axin-2 protein 20130413 {GO:0008219=IEA, GO:0005881=IBA, GO:0008285=IMP, GO:0008013=NAS, GO:0005886=IBA, GO:0008283=IEA, GO:0003413=IEA, GO:0001756=IEA, GO:0030877=NAS, GO:0010718=IMP, GO:0038032=IEA, GO:0005634=IDA, GO:0030282=IEA, GO:0090244=IBA, GO:0035414=IMP, GO:0009950=IBA, GO:0005622=IEA, GO:2000054=IEA, GO:0005737=IDA, GO:0045860=IEA, GO:0042476=IMP, GO:0048255=IMP, GO:0004871=IEA, GO:0090090=IMP, GO:0010942=IMP, GO:0005938=IBA, GO:0031625=IPI, GO:0070602=IMP, GO:0005813=IDA, GO:0019901=IBA, GO:0061181=IEA, GO:0014069=IBA, GO:0070411=IEA, GO:0007275=IEA, GO:0032423=IMP, GO:0043570=IMP, GO:0043547=IBA, GO:0043234=IEA, GO:0071407=IBA, GO:0001957=IBA, GO:0045668=IBA, GO:0001934=IMP, GO:0016023=IBA, GO:0034613=IDA, GO:0019899=IPI, GO:0070016=IBA, GO:0005096=IBA} Wnt receptor signaling pathway involved in somitogenesis, bone mineralization, cell death, cell proliferation, cellular protein localization, cellular response to organic cyclic compound, chondrocyte differentiation involved in endochondral bone morphogenesis, dorsal/ventral axis specification, intramembranous ossification, mRNA stabilization, maintenance of DNA repeat elements, multicellular organismal development, negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of catenin import into nucleus, negative regulation of cell proliferation, negative regulation of osteoblast differentiation, odontogenesis, positive regulation of GTPase activity, positive regulation of cell death, positive regulation of epithelial to mesenchymal transition, positive regulation of protein kinase activity, positive regulation of protein phosphorylation, regulation of centromeric sister chromatid cohesion, regulation of chondrocyte development, regulation of mismatch repair, somitogenesis, termination of G-protein coupled receptor signaling pathway beta-catenin destruction complex, cell cortex, centrosome, cytoplasm, cytoplasmic membrane-bounded vesicle, cytoplasmic microtubule, intracellular, nucleus, plasma membrane, postsynaptic density, protein complex GTPase activator activity, I-SMAD binding, armadillo repeat domain binding, beta-catenin binding, enzyme binding, protein kinase binding, signal transducer activity, ubiquitin protein ligase binding Human PANTHER:PTN000090250 AXL PINC UniProtKB {GO:0006909=PMID:21501828, GO:0005515=PMID:20088931, GO:0051897=GO_REF:0000019, GO:0060068=GO_REF:0000019, GO:0034101=GO_REF:0000019, GO:0042698=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0005615=PMID:20088931, GO:0043524=GO_REF:0000019, GO:0006954=GO_REF:0000019, GO:0031668=GO_REF:0000019, GO:0034446=GO_REF:0000019, GO:0001779=GO_REF:0000019, GO:0009986=PMID:19657094, GO:0046982=GO_REF:0000019, GO:0030168=GO_REF:0000019, GO:0032720=GO_REF:0000019, GO:0043277=GO_REF:0000019, GO:2000669=PMID:19657094, GO:0005524=GO_REF:0000037, GO:0007165=PMID:1656220, GO:0071222=PMID:19657094, GO:0005887=PMID:1656220, GO:0001974=GO_REF:0000019, GO:0045087=GO_REF:0000037, GO:0001786=PMID:21501828, GO:0043491=GO_REF:0000019, GO:0051250=GO_REF:0000019, GO:0021885=GO_REF:0000019, GO:0004713=GO_REF:0000002, GO:0001764=GO_REF:0000019, GO:0004714=GO_REF:0000003, GO:0032940=GO_REF:0000019, GO:0007167=GO_REF:0000019} P30530 Tyrosine-protein kinase receptor UFO protein 20030904 {GO:0006909=IDA, GO:0005515=IPI, GO:0051897=IEA, GO:0060068=IEA, GO:0034101=IEA, GO:0042698=IEA, GO:0007283=IEA, GO:0005615=IDA, GO:0043524=IEA, GO:0006954=IEA, GO:0031668=IEA, GO:0034446=IEA, GO:0001779=IEA, GO:0009986=IDA, GO:0046982=IEA, GO:0030168=IEA, GO:0032720=IEA, GO:0043277=IEA, GO:2000669=IDA, GO:0005524=IEA, GO:0007165=TAS, GO:0071222=IDA, GO:0005887=TAS, GO:0001974=IEA, GO:0045087=IEA, GO:0001786=IDA, GO:0043491=IEA, GO:0051250=IEA, GO:0021885=IEA, GO:0004713=IEA, GO:0001764=IEA, GO:0004714=IEA, GO:0032940=IEA, GO:0007167=IEA} apoptotic cell clearance, blood vessel remodeling, cellular response to extracellular stimulus, cellular response to lipopolysaccharide, enzyme linked receptor protein signaling pathway, erythrocyte homeostasis, forebrain cell migration, inflammatory response, innate immune response, natural killer cell differentiation, negative regulation of dendritic cell apoptotic process, negative regulation of lymphocyte activation, negative regulation of neuron apoptotic process, negative regulation of tumor necrosis factor production, neuron migration, ovulation cycle, phagocytosis, platelet activation, positive regulation of protein kinase B signaling cascade, protein kinase B signaling cascade, secretion by cell, signal transduction, spermatogenesis, substrate adhesion-dependent cell spreading, vagina development cell surface, extracellular space, integral to plasma membrane ATP binding, phosphatidylserine binding, protein binding, protein heterodimerization activity, protein tyrosine kinase activity, transmembrane receptor protein tyrosine kinase activity Human AZGP1 UniProtKB UniProtKB {GO:0006955=GO_REF:0000002, GO:0008285=PMID:10462714, GO:0019882=GO_REF:0000002, GO:0042612=GO_REF:0000002, GO:0004540=PMID:10462714, GO:0005576=PMID:14718574, GO:0008320=PMID:6896906, GO:0007155=GO_REF:0000024} P25311 Zinc-alpha-2-glycoprotein protein 20040512 {GO:0006955=IEA, GO:0008285=NAS, GO:0019882=IEA, GO:0042612=IEA, GO:0004540=NAS, GO:0005576=NAS, GO:0008320=NAS, GO:0007155=ISS} antigen processing and presentation, cell adhesion, immune response, negative regulation of cell proliferation MHC class I protein complex, extracellular region protein transmembrane transporter activity, ribonuclease activity Human AZI1 HPA UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005813=GO_REF:0000052, GO:0000086=Reactome:REACT_2203, GO:0015630=GO_REF:0000052, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0000278=Reactome:REACT_152, GO:0030154=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0005829=Reactome:REACT_15470} Q9UPN4 5-azacytidine-induced protein 1 protein 20101115 {GO:0003674=ND, GO:0008150=ND, GO:0005813=IDA, GO:0000086=TAS, GO:0015630=IDA, GO:0007275=IEA, GO:0007283=IEA, GO:0000278=TAS, GO:0030154=IEA, GO:0043231=IDA, GO:0005829=TAS} G2/M transition of mitotic cell cycle, biological_process, cell differentiation, mitotic cell cycle, multicellular organismal development, spermatogenesis centrosome, cytosol, intracellular membrane-bounded organelle, microtubule cytoskeleton molecular_function Human AZI2 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0007249=GO_REF:0000019} Q9H6S1 5-azacytidine-induced protein 2 protein 20101115 {GO:0005739=IDA, GO:0005737=IDA, GO:0005886=IDA, GO:0007249=IEA} I-kappaB kinase/NF-kappaB cascade cytoplasm, mitochondrion, plasma membrane Human AZIN1 GOC UniProtKB {GO:0004857=PMID:9349715, GO:0042978=GO_REF:0000019, GO:0034641=Reactome:REACT_13, GO:0006596=GO_REF:0000037, GO:0006521=Reactome:REACT_13565, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0043086=PMID:9349715, GO:0005829=Reactome:REACT_13578} O14977 Antizyme inhibitor 1 protein 20130413 {GO:0004857=TAS, GO:0042978=IEA, GO:0034641=TAS, GO:0006596=IEA, GO:0006521=TAS, GO:0044281=TAS, GO:0003824=IEA, GO:0043086=TAS, GO:0005829=TAS} cellular nitrogen compound metabolic process, negative regulation of catalytic activity, polyamine biosynthetic process, regulation of cellular amino acid metabolic process, small molecule metabolic process cytosol catalytic activity, enzyme inhibitor activity, ornithine decarboxylase activator activity Human AZU1 UniProtKB UniProtKB {GO:0043066=PMID:10510329, GO:0004252=GO_REF:0000002, GO:0008347=PMID:12465046, GO:0042535=PMID:12465046, GO:0042582=PMID:11861296, GO:0050725=PMID:12465046, GO:0005576=PMID:11861296, GO:0007205=PMID:12465046, GO:0045785=PMID:12826073, GO:0050930=PMID:12465046, GO:0045348=PMID:12465046, GO:0050829=PMID:12465046, GO:0050766=PMID:12465046, GO:0050754=PMID:12465046, GO:0006954=PMID:12678126, GO:0042117=PMID:12465046, GO:0015643=PMID:10534120, GO:0045123=PMID:11861296, GO:0006508=GO_REF:0000002, GO:0043114=PMID:11861296, GO:0048246=PMID:1919011, GO:0001774=PMID:12465046, GO:0008201=PMID:11994286} P20160 Azurocidin protein 20031111 {GO:0043066=NAS, GO:0004252=IEA, GO:0008347=IDA, GO:0042535=IDA, GO:0042582=IDA, GO:0050725=IDA, GO:0005576=NAS, GO:0007205=TAS, GO:0045785=IDA, GO:0050930=NAS, GO:0045348=IEP, GO:0050829=TAS, GO:0050766=IDA, GO:0050754=IDA, GO:0006954=NAS, GO:0042117=TAS, GO:0015643=NAS, GO:0045123=NAS, GO:0006508=IEA, GO:0043114=NAS, GO:0048246=NAS, GO:0001774=IEP, GO:0008201=NAS} cellular extravasation, defense response to Gram-negative bacterium, glial cell migration, induction of positive chemotaxis, inflammatory response, macrophage chemotaxis, microglial cell activation, monocyte activation, negative regulation of apoptotic process, positive regulation of MHC class II biosynthetic process, positive regulation of cell adhesion, positive regulation of fractalkine biosynthetic process, positive regulation of interleukin-1 beta biosynthetic process, positive regulation of phagocytosis, positive regulation of tumor necrosis factor biosynthetic process, protein kinase C-activating G-protein coupled receptor signaling pathway, proteolysis, regulation of vascular permeability azurophil granule, extracellular region heparin binding, serine-type endopeptidase activity, toxic substance binding Human B2M IntAct UniProtKB {GO:0005515=PMID:15723809, GO:0002474=Reactome:REACT_75820, GO:0005886=Reactome:REACT_147879, GO:0019221=Reactome:REACT_25229, GO:0002237=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0042026=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0006955=GO_REF:0000002, GO:0030670=Reactome:REACT_111215, GO:0016032=Reactome:REACT_6185, GO:0060333=Reactome:REACT_25078, GO:0012507=Reactome:REACT_75894, GO:0033077=GO_REF:0000019, GO:0002480=Reactome:REACT_111168, GO:0002481=GO_REF:0000019, GO:0005794=GO_REF:0000052, GO:0042612=GO_REF:0000037, GO:0042493=GO_REF:0000019, GO:0042590=Reactome:REACT_111119, GO:0005576=Reactome:REACT_75876, GO:0050690=Reactome:REACT_11149, GO:0031905=Reactome:REACT_111222, GO:0000139=Reactome:REACT_75894, GO:0001916=GO_REF:0000019, GO:0031901=Reactome:REACT_11229, GO:0045087=Reactome:REACT_6802, GO:0050776=Reactome:REACT_11152, GO:0002479=Reactome:REACT_111178, GO:0005788=Reactome:REACT_75922, GO:0009897=GO_REF:0000019, GO:0046686=GO_REF:0000019} P61769 Beta-2-microglobulin protein 20130415 {GO:0005515=IPI, GO:0002474=TAS, GO:0005886=TAS, GO:0019221=TAS, GO:0002237=IEA, GO:0005615=IEA, GO:0042026=IEA, GO:0005737=IDA, GO:0006955=IEA, GO:0030670=TAS, GO:0016032=TAS, GO:0060333=TAS, GO:0012507=TAS, GO:0033077=IEA, GO:0002480=TAS, GO:0002481=IEA, GO:0005794=IDA, GO:0042612=IEA, GO:0042493=IEA, GO:0042590=TAS, GO:0005576=TAS, GO:0050690=TAS, GO:0031905=TAS, GO:0000139=TAS, GO:0001916=IEA, GO:0031901=TAS, GO:0045087=TAS, GO:0050776=TAS, GO:0002479=TAS, GO:0005788=TAS, GO:0009897=IEA, GO:0046686=IEA} T cell differentiation in thymus, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent, antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, cytokine-mediated signaling pathway, immune response, innate immune response, interferon-gamma-mediated signaling pathway, positive regulation of T cell mediated cytotoxicity, protein refolding, regulation of defense response to virus by virus, regulation of immune response, response to cadmium ion, response to drug, response to molecule of bacterial origin, viral reproduction ER to Golgi transport vesicle membrane, Golgi apparatus, Golgi membrane, MHC class I protein complex, cytoplasm, early endosome lumen, early endosome membrane, endoplasmic reticulum lumen, external side of plasma membrane, extracellular region, extracellular space, phagocytic vesicle membrane, plasma membrane protein binding Human UniProtKB:P06126 B3GALNT1 UniPathway UniProtKB {GO:0009312=GO_REF:0000019, GO:0000139=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0008499=GO_REF:0000019, GO:0006486=GO_REF:0000041, GO:0016021=GO_REF:0000037, GO:0047273=GO_REF:0000003, GO:0008378=GO_REF:0000002} O75752 UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 protein 20130413 {GO:0009312=IEA, GO:0000139=IEA, GO:0016020=IEA, GO:0008499=IEA, GO:0006486=IEA, GO:0016021=IEA, GO:0047273=IEA, GO:0008378=IEA} oligosaccharide biosynthetic process, protein glycosylation Golgi membrane, integral to membrane, membrane UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity, galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity, galactosyltransferase activity Human UniPathway:UPA00378 B3GALNT2 UniPathway UniProtKB {GO:0000139=GO_REF:0000039, GO:0006486=GO_REF:0000041, GO:0016021=GO_REF:0000037, GO:0008378=GO_REF:0000002} Q8NCR0 UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2 protein 20130413 {GO:0000139=IEA, GO:0006486=IEA, GO:0016021=IEA, GO:0008378=IEA} protein glycosylation Golgi membrane, integral to membrane galactosyltransferase activity Human UniPathway:UPA00378 B3GALT1 UniProtKB UniProtKB {GO:0009312=GO_REF:0000019, GO:0000139=GO_REF:0000039, GO:0008499=PMID:9582303, GO:0006486=GO_REF:0000041, GO:0016021=PMID:9582303, GO:0030259=GO_REF:0000029} Q9Y5Z6 Beta-1,3-galactosyltransferase 1 protein 20021106 {GO:0009312=IEA, GO:0000139=IEA, GO:0008499=IDA, GO:0006486=IEA, GO:0016021=NAS, GO:0030259=NAS} lipid glycosylation, oligosaccharide biosynthetic process, protein glycosylation Golgi membrane, integral to membrane UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity Human B3GALT2 UniPathway UniProtKB {GO:0009312=GO_REF:0000019, GO:0000139=GO_REF:0000039, GO:0008499=GO_REF:0000019, GO:0006486=GO_REF:0000041, GO:0016021=GO_REF:0000037} O43825 Beta-1,3-galactosyltransferase 2 protein 20130413 {GO:0009312=IEA, GO:0000139=IEA, GO:0008499=IEA, GO:0006486=IEA, GO:0016021=IEA} oligosaccharide biosynthetic process, protein glycosylation Golgi membrane, integral to membrane UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity Human UniPathway:UPA00378 B3GALT4 PINC UniProtKB {GO:0000139=GO_REF:0000039, GO:0008499=PMID:9582303, GO:0047915=GO_REF:0000003, GO:0006486=GO_REF:0000041, GO:0016021=GO_REF:0000037} O96024 Beta-1,3-galactosyltransferase 4 protein 20030904 {GO:0000139=IEA, GO:0008499=TAS, GO:0047915=IEA, GO:0006486=IEA, GO:0016021=IEA} protein glycosylation Golgi membrane, integral to membrane UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity, ganglioside galactosyltransferase activity Human B3GALT6 Reactome UniProtKB {GO:0008499=GO_REF:0000019, GO:0005975=Reactome:REACT_474, GO:0005797=PMID:11551958, GO:0044281=Reactome:REACT_111217, GO:0015012=GO_REF:0000041, GO:0006024=PMID:11551958, GO:0030206=GO_REF:0000041, GO:0035250=PMID:11551958, GO:0000139=Reactome:REACT_121213, GO:0032580=GO_REF:0000039, GO:0006486=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408, GO:0047220=GO_REF:0000003} Q96L58 Beta-1,3-galactosyltransferase 6 protein 20130301 {GO:0008499=IEA, GO:0005975=TAS, GO:0005797=IDA, GO:0044281=TAS, GO:0015012=IEA, GO:0006024=IMP, GO:0030206=IEA, GO:0035250=IDA, GO:0000139=TAS, GO:0032580=IEA, GO:0006486=IEA, GO:0016021=IEA, GO:0030204=TAS, GO:0030203=TAS, GO:0047220=IEA} carbohydrate metabolic process, chondroitin sulfate biosynthetic process, chondroitin sulfate metabolic process, glycosaminoglycan biosynthetic process, glycosaminoglycan metabolic process, heparan sulfate proteoglycan biosynthetic process, protein glycosylation, small molecule metabolic process Golgi cisterna membrane, Golgi medial cisterna, Golgi membrane, integral to membrane UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity, UDP-galactosyltransferase activity, galactosylxylosylprotein 3-beta-galactosyltransferase activity Human B3GALTL UniPathway UniProtKB {GO:0016757=GO_REF:0000037, GO:0005789=GO_REF:0000039, GO:0006486=GO_REF:0000041, GO:0016021=GO_REF:0000037, GO:0006004=GO_REF:0000037} Q6Y288 Beta-1,3-glucosyltransferase protein 20130413 {GO:0016757=IEA, GO:0005789=IEA, GO:0006486=IEA, GO:0016021=IEA, GO:0006004=IEA} fucose metabolic process, protein glycosylation endoplasmic reticulum membrane, integral to membrane transferase activity, transferring glycosyl groups Human UniPathway:UPA00378 B3GAT1 Reactome UniProtKB {GO:0015018=GO_REF:0000003, GO:0000139=Reactome:REACT_120897, GO:0016020=GO_REF:0000002, GO:0005975=Reactome:REACT_474, GO:0008499=GO_REF:0000019, GO:0006486=GO_REF:0000041, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408, GO:0046872=GO_REF:0000037} Q9P2W7 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 protein 20111101 {GO:0015018=IEA, GO:0000139=TAS, GO:0016020=IEA, GO:0005975=TAS, GO:0008499=IEA, GO:0006486=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0030204=TAS, GO:0030203=TAS, GO:0046872=IEA} carbohydrate metabolic process, chondroitin sulfate metabolic process, glycosaminoglycan metabolic process, protein glycosylation, small molecule metabolic process Golgi membrane, integral to membrane, membrane UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity, galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity, metal ion binding Human B3GAT3 Reactome UniProtKB {GO:0005801=PMID:21763480, GO:0050650=PMID:21763480, GO:0030145=GO_REF:0000029, GO:0005794=PMID:21763480, GO:0050651=PMID:21763480, GO:0005975=Reactome:REACT_474, GO:0015020=PMID:21763480, GO:0044281=Reactome:REACT_111217, GO:0015012=PMID:21763480, GO:0006024=PMID:10842173, GO:0015018=PMID:10842173, GO:0016020=GO_REF:0000002, GO:0000139=Reactome:REACT_120897, GO:0006486=GO_REF:0000041, GO:0016021=PMID:10842173, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408} O94766 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 protein 20111101 {GO:0005801=IDA, GO:0050650=IDA, GO:0030145=NAS, GO:0005794=IDA, GO:0050651=IDA, GO:0005975=TAS, GO:0015020=IMP, GO:0044281=TAS, GO:0015012=IDA, GO:0006024=NAS, GO:0015018=NAS, GO:0016020=IEA, GO:0000139=TAS, GO:0006486=IEA, GO:0016021=NAS, GO:0030204=TAS, GO:0030203=TAS} carbohydrate metabolic process, chondroitin sulfate metabolic process, chondroitin sulfate proteoglycan biosynthetic process, dermatan sulfate proteoglycan biosynthetic process, glycosaminoglycan biosynthetic process, glycosaminoglycan metabolic process, heparan sulfate proteoglycan biosynthetic process, protein glycosylation, small molecule metabolic process Golgi apparatus, Golgi membrane, cis-Golgi network, integral to membrane, membrane galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity, glucuronosyltransferase activity, manganese ion binding Human B3GNT1 Reactome UniProtKB {GO:0030173=PMID:9405606, GO:0008532=PMID:9405606, GO:0018146=Reactome:REACT_121120, GO:0000139=Reactome:REACT_121143, GO:0005975=Reactome:REACT_474, GO:0030311=PMID:9405606, GO:0006486=GO_REF:0000041, GO:0044281=Reactome:REACT_111217, GO:0030203=Reactome:REACT_121315, GO:0042339=Reactome:REACT_121288} O43505 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase protein 20130301 {GO:0030173=NAS, GO:0008532=IDA, GO:0018146=TAS, GO:0000139=TAS, GO:0005975=TAS, GO:0030311=IDA, GO:0006486=IEA, GO:0044281=TAS, GO:0030203=TAS, GO:0042339=TAS} carbohydrate metabolic process, glycosaminoglycan metabolic process, keratan sulfate biosynthetic process, keratan sulfate metabolic process, poly-N-acetyllactosamine biosynthetic process, protein glycosylation, small molecule metabolic process Golgi membrane, integral to Golgi membrane N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity Human B3GNT2 Reactome UniProtKB {GO:0007608=GO_REF:0000019, GO:0008499=GO_REF:0000029, GO:0005975=Reactome:REACT_474, GO:0016266=Reactome:REACT_115606, GO:0044281=Reactome:REACT_111217, GO:0042339=Reactome:REACT_121288, GO:0008150=GO_REF:0000015, GO:0000139=Reactome:REACT_121143, GO:0018146=Reactome:REACT_121120, GO:0007411=GO_REF:0000019, GO:0016021=GO_REF:0000029, GO:0030203=Reactome:REACT_121315, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q9NY97 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 protein 20130301 {GO:0007608=IEA, GO:0008499=NAS, GO:0005975=TAS, GO:0016266=TAS, GO:0044281=TAS, GO:0042339=TAS, GO:0008150=ND, GO:0000139=TAS, GO:0018146=TAS, GO:0007411=IEA, GO:0016021=NAS, GO:0030203=TAS, GO:0044267=TAS, GO:0043687=TAS} O-glycan processing, axon guidance, biological_process, carbohydrate metabolic process, cellular protein metabolic process, glycosaminoglycan metabolic process, keratan sulfate biosynthetic process, keratan sulfate metabolic process, post-translational protein modification, sensory perception of smell, small molecule metabolic process Golgi membrane, integral to membrane UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity Human B3GNT4 Reactome UniProtKB {GO:0018146=Reactome:REACT_121120, GO:0000139=Reactome:REACT_121143, GO:0005975=Reactome:REACT_474, GO:0016266=Reactome:REACT_115606, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0030203=Reactome:REACT_121315, GO:0008378=GO_REF:0000002, GO:0043687=Reactome:REACT_22161, GO:0042339=Reactome:REACT_121288} Q9C0J1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 protein 20130301 {GO:0018146=TAS, GO:0000139=TAS, GO:0005975=TAS, GO:0016266=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0044267=TAS, GO:0030203=TAS, GO:0008378=IEA, GO:0043687=TAS, GO:0042339=TAS} O-glycan processing, carbohydrate metabolic process, cellular protein metabolic process, glycosaminoglycan metabolic process, keratan sulfate biosynthetic process, keratan sulfate metabolic process, post-translational protein modification, small molecule metabolic process Golgi membrane, integral to membrane galactosyltransferase activity Human B3GNT5 Reactome UniProtKB {GO:0009247=PMID:11384981, GO:0047256=GO_REF:0000003, GO:0016266=Reactome:REACT_115606, GO:0008457=PMID:11384981, GO:0007417=PMID:11384981, GO:0008378=GO_REF:0000002, GO:0005622=PMID:11384981, GO:0016020=GO_REF:0000002, GO:0000139=Reactome:REACT_116000, GO:0006486=PMID:11384981, GO:0016021=GO_REF:0000037, GO:0008917=GO_REF:0000019, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q9BYG0 Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase protein 20130301 {GO:0009247=TAS, GO:0047256=IEA, GO:0016266=TAS, GO:0008457=IDA, GO:0007417=IDA, GO:0008378=IEA, GO:0005622=IDA, GO:0016020=IEA, GO:0000139=TAS, GO:0006486=TAS, GO:0016021=IEA, GO:0008917=IEA, GO:0044267=TAS, GO:0043687=TAS} O-glycan processing, cellular protein metabolic process, central nervous system development, glycolipid biosynthetic process, post-translational protein modification, protein glycosylation Golgi membrane, integral to membrane, intracellular, membrane beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity, galactosyltransferase activity, lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity, lipopolysaccharide N-acetylglucosaminyltransferase activity Human B3GNT9 UniProtKB UniProtKB {GO:0000139=GO_REF:0000039, GO:0006486=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0008378=GO_REF:0000002} Q6UX72 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 protein 20130413 {GO:0000139=IEA, GO:0006486=IEA, GO:0016021=IEA, GO:0008378=IEA} protein glycosylation Golgi membrane, integral to membrane galactosyltransferase activity Human UniProtKB-SubCell:SL-0134 B3GNTL1 UniProtKB UniProtKB {GO:0016757=GO_REF:0000037} Q67FW5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 protein 20130413 {GO:0016757=IEA} transferase activity, transferring glycosyl groups Human UniProtKB-KW:KW-0328 B4GALNT1 PINC UniProtKB {GO:0005886=GO_REF:0000019, GO:0006687=PMID:1601877, GO:0016757=GO_REF:0000038, GO:0019915=GO_REF:0000019, GO:0005975=PMID:1601877, GO:0007283=GO_REF:0000019, GO:0008376=GO_REF:0000019, GO:0030173=GO_REF:0000002, GO:0016020=PMID:1601877, GO:0003947=GO_REF:0000003, GO:0001574=GO_REF:0000019, GO:0006486=GO_REF:0000041, GO:0030259=GO_REF:0000002} Q00973 Beta-1,4 N-acetylgalactosaminyltransferase 1 protein 20030904 {GO:0005886=IEA, GO:0006687=TAS, GO:0016757=IEA, GO:0019915=IEA, GO:0005975=TAS, GO:0007283=IEA, GO:0008376=IEA, GO:0030173=IEA, GO:0016020=TAS, GO:0003947=IEA, GO:0001574=IEA, GO:0006486=IEA, GO:0030259=IEA} carbohydrate metabolic process, ganglioside biosynthetic process, glycosphingolipid metabolic process, lipid glycosylation, lipid storage, protein glycosylation, spermatogenesis integral to Golgi membrane, membrane, plasma membrane (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity, acetylgalactosaminyltransferase activity, transferase activity, transferring glycosyl groups Human B4GALT1 HPA UniProtKB {GO:0008092=GO_REF:0000019, GO:0030057=PMID:3917437, GO:0060046=GO_REF:0000019, GO:0030112=PMID:3917437, GO:0030879=GO_REF:0000019, GO:0031526=PMID:3917437, GO:0050900=GO_REF:0000019, GO:0009101=GO_REF:0000019, GO:0003945=PMID:2120039, GO:0007219=Reactome:REACT_299, GO:0030198=GO_REF:0000019, GO:0002064=GO_REF:0000019, GO:0030203=Reactome:REACT_121315, GO:0018279=Reactome:REACT_22426, GO:0002526=GO_REF:0000019, GO:0005794=GO_REF:0000052, GO:0009986=GO_REF:0000019, GO:0016757=GO_REF:0000002, GO:0005975=GO_REF:0000002, GO:0004461=PMID:33805, GO:0008378=PMID:7540104, GO:0044267=Reactome:REACT_17015, GO:0009897=PMID:3917437, GO:0043687=Reactome:REACT_22161, GO:0005989=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0016323=PMID:3917437, GO:0032580=GO_REF:0000039, GO:0007155=GO_REF:0000019, GO:0060054=GO_REF:0000019, GO:0009312=PMID:2120039, GO:0060058=GO_REF:0000019, GO:0060055=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0003831=PMID:33805, GO:0045136=GO_REF:0000019, GO:0007339=GO_REF:0000019, GO:0042339=Reactome:REACT_121288, GO:0035250=PMID:3917437, GO:0000139=Reactome:REACT_120962, GO:0018146=Reactome:REACT_121120, GO:0000138=PMID:6121819, GO:0007341=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0048754=GO_REF:0000019, GO:0006012=GO_REF:0000019, GO:0051270=GO_REF:0000019} Q86XA6 Lactose synthase A protein protein 20080205 {GO:0008092=IEA, GO:0030057=IDA, GO:0060046=IEA, GO:0030112=IDA, GO:0030879=IEA, GO:0031526=IDA, GO:0050900=IEA, GO:0009101=IEA, GO:0003945=IDA, GO:0007219=TAS, GO:0030198=IEA, GO:0002064=IEA, GO:0030203=TAS, GO:0018279=TAS, GO:0002526=IEA, GO:0005794=IDA, GO:0009986=IEA, GO:0016757=IEA, GO:0005975=IEA, GO:0004461=IDA, GO:0008378=NAS, GO:0044267=TAS, GO:0009897=IDA, GO:0043687=TAS, GO:0005989=IEA, GO:0008285=IEA, GO:0005886=IEA, GO:0044281=TAS, GO:0046872=IEA, GO:0016323=IDA, GO:0032580=IEA, GO:0007155=IEA, GO:0060054=IEA, GO:0009312=IDA, GO:0060058=IEA, GO:0060055=IEA, GO:0005576=IEA, GO:0003831=IDA, GO:0045136=IEA, GO:0007339=IEA, GO:0042339=TAS, GO:0035250=IDA, GO:0000139=TAS, GO:0018146=TAS, GO:0000138=IDA, GO:0007341=IEA, GO:0016021=IEA, GO:0048754=IEA, GO:0006012=IEA, GO:0051270=IEA} Notch signaling pathway, acute inflammatory response, angiogenesis involved in wound healing, binding of sperm to zona pellucida, branching morphogenesis of an epithelial tube, carbohydrate metabolic process, cell adhesion, cellular protein metabolic process, development of secondary sexual characteristics, epithelial cell development, extracellular matrix organization, galactose metabolic process, glycoprotein biosynthetic process, glycosaminoglycan metabolic process, keratan sulfate biosynthetic process, keratan sulfate metabolic process, lactose biosynthetic process, leukocyte migration, mammary gland development, negative regulation of cell proliferation, oligosaccharide biosynthetic process, penetration of zona pellucida, positive regulation of apoptotic process involved in mammary gland involution, positive regulation of epithelial cell proliferation involved in wound healing, post-translational protein modification, protein N-linked glycosylation via asparagine, regulation of acrosome reaction, regulation of cellular component movement, small molecule metabolic process Golgi apparatus, Golgi cisterna membrane, Golgi membrane, Golgi trans cisterna, basolateral plasma membrane, brush border membrane, cell surface, desmosome, external side of plasma membrane, extracellular region, glycocalyx, integral to membrane, plasma membrane N-acetyllactosamine synthase activity, UDP-galactosyltransferase activity, beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity, cytoskeletal protein binding, galactosyltransferase activity, lactose synthase activity, metal ion binding, transferase activity, transferring glycosyl groups Human B4GALT2 Reactome UniProtKB {GO:0005975=Reactome:REACT_474, GO:0004461=GO_REF:0000003, GO:0003831=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0008378=PMID:9405390, GO:0046872=GO_REF:0000037, GO:0042339=Reactome:REACT_121288, GO:0003945=GO_REF:0000003, GO:0000139=Reactome:REACT_120962, GO:0018146=Reactome:REACT_121120, GO:0032580=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0030203=Reactome:REACT_121315, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} O60909 Beta-1,4-galactosyltransferase 2 protein 20101008 {GO:0005975=TAS, GO:0004461=IEA, GO:0003831=IEA, GO:0044281=TAS, GO:0008378=TAS, GO:0046872=IEA, GO:0042339=TAS, GO:0003945=IEA, GO:0000139=TAS, GO:0018146=TAS, GO:0032580=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0030203=TAS, GO:0043687=TAS, GO:0018279=TAS} carbohydrate metabolic process, cellular protein metabolic process, glycosaminoglycan metabolic process, keratan sulfate biosynthetic process, keratan sulfate metabolic process, post-translational protein modification, protein N-linked glycosylation via asparagine, small molecule metabolic process Golgi cisterna membrane, Golgi membrane, integral to membrane N-acetyllactosamine synthase activity, beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity, galactosyltransferase activity, lactose synthase activity, metal ion binding Human B4GALT3 HPA UniProtKB {GO:0005794=GO_REF:0000052, GO:0005975=Reactome:REACT_474, GO:0003831=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0008378=PMID:9405390, GO:0046872=GO_REF:0000037, GO:0042339=Reactome:REACT_121288, GO:0005737=GO_REF:0000052, GO:0003945=GO_REF:0000003, GO:0000139=Reactome:REACT_120962, GO:0018146=Reactome:REACT_121120, GO:0032580=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0030203=Reactome:REACT_121315, GO:0018279=Reactome:REACT_22426, GO:0043687=Reactome:REACT_22161} O60512 Beta-1,4-galactosyltransferase 3 protein 20080205 {GO:0005794=IDA, GO:0005975=TAS, GO:0003831=IEA, GO:0044281=TAS, GO:0008378=TAS, GO:0046872=IEA, GO:0042339=TAS, GO:0005737=IDA, GO:0003945=IEA, GO:0000139=TAS, GO:0018146=TAS, GO:0032580=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0030203=TAS, GO:0018279=TAS, GO:0043687=TAS} carbohydrate metabolic process, cellular protein metabolic process, glycosaminoglycan metabolic process, keratan sulfate biosynthetic process, keratan sulfate metabolic process, post-translational protein modification, protein N-linked glycosylation via asparagine, small molecule metabolic process Golgi apparatus, Golgi cisterna membrane, Golgi membrane, cytoplasm, integral to membrane N-acetyllactosamine synthase activity, beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity, galactosyltransferase activity, metal ion binding Human B4GALT5 Reactome UniProtKB {GO:0005975=Reactome:REACT_474, GO:0016266=Reactome:REACT_115606, GO:0044281=Reactome:REACT_111217, GO:0008378=PMID:9597550, GO:0046872=GO_REF:0000037, GO:0042339=Reactome:REACT_121288, GO:0000139=Reactome:REACT_120962, GO:0018146=Reactome:REACT_121120, GO:0032580=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0030203=Reactome:REACT_121315, GO:0044267=Reactome:REACT_17015, GO:0018279=Reactome:REACT_22426, GO:0043687=Reactome:REACT_22161} O43286 Beta-1,4-galactosyltransferase 5 protein 20101115 {GO:0005975=TAS, GO:0016266=TAS, GO:0044281=TAS, GO:0008378=TAS, GO:0046872=IEA, GO:0042339=TAS, GO:0000139=TAS, GO:0018146=TAS, GO:0032580=IEA, GO:0016021=IEA, GO:0030203=TAS, GO:0044267=TAS, GO:0018279=TAS, GO:0043687=TAS} O-glycan processing, carbohydrate metabolic process, cellular protein metabolic process, glycosaminoglycan metabolic process, keratan sulfate biosynthetic process, keratan sulfate metabolic process, post-translational protein modification, protein N-linked glycosylation via asparagine, small molecule metabolic process Golgi cisterna membrane, Golgi membrane, integral to membrane galactosyltransferase activity, metal ion binding Human B9D1 UniProtKB UniProtKB {GO:0042384=GO_REF:0000024, GO:0005813=PMID:19208769, GO:0035869=GO_REF:0000024, GO:0060271=GO_REF:0000024, GO:0036038=GO_REF:0000024, GO:0008158=GO_REF:0000024, GO:0005932=PMID:19208769, GO:0035085=GO_REF:0000039, GO:0007224=GO_REF:0000024} Q9UPM9 B9 domain-containing protein 1 protein 20110125 {GO:0042384=ISS, GO:0005813=IDA, GO:0035869=ISS, GO:0060271=ISS, GO:0036038=ISS, GO:0008158=ISS, GO:0005932=IDA, GO:0035085=IEA, GO:0007224=ISS} cilium assembly, cilium morphogenesis, smoothened signaling pathway TCTN-B9D complex, centrosome, ciliary transition zone, cilium axoneme, microtubule basal body hedgehog receptor activity Human UniProtKB:Q9NXB0 B9D2 Reactome UniProtKB {GO:0000236=Reactome:REACT_682, GO:0042384=GO_REF:0000024, GO:0005813=PMID:19208769, GO:0043015=GO_REF:0000024, GO:0000087=Reactome:REACT_910, GO:0036038=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0005932=PMID:19208769, GO:0000278=Reactome:REACT_152, GO:0035085=GO_REF:0000039, GO:0000090=Reactome:REACT_1275, GO:0005829=Reactome:REACT_150414} Q9BPU9 B9 domain-containing protein 2 protein 20130213 {GO:0000236=TAS, GO:0042384=ISS, GO:0005813=IDA, GO:0043015=ISS, GO:0000087=TAS, GO:0036038=ISS, GO:0005634=IEA, GO:0005932=IDA, GO:0000278=TAS, GO:0035085=IEA, GO:0000090=TAS, GO:0005829=TAS} M phase of mitotic cell cycle, cilium assembly, mitotic anaphase, mitotic cell cycle, mitotic prometaphase TCTN-B9D complex, centrosome, cilium axoneme, cytosol, microtubule basal body, nucleus gamma-tubulin binding Human BAALC HPA UniProtKB {GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0016020=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q8WXS3 Brain and acute leukemia cytoplasmic protein protein 20101115 {GO:0005813=IDA, GO:0005737=IDA, GO:0016020=IEA, GO:0005730=IDA, GO:0005634=IDA} centrosome, cytoplasm, membrane, nucleolus, nucleus Human BAAT Reactome UniProtKB {GO:0004091=GO_REF:0000037, GO:0052815=PMID:12810727, GO:0006637=PMID:12810727, GO:0052817=PMID:12810727, GO:0016410=PMID:12239217, GO:0052816=PMID:12810727, GO:0005782=Reactome:REACT_9974, GO:0006699=Reactome:REACT_11054, GO:0019530=PMID:8034703, GO:0016290=GO_REF:0000003, GO:0002152=PMID:8034703, GO:0031100=GO_REF:0000019, GO:0005102=PMID:20178365, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_9991, GO:0001889=GO_REF:0000019, GO:0015721=Reactome:REACT_11042, GO:0006631=GO_REF:0000037, GO:0006544=PMID:8034703, GO:0008206=Reactome:REACT_11040, GO:0047963=PMID:8034703} Q14032 Bile acid-CoA:amino acid N-acyltransferase protein 20130301 {GO:0004091=IEA, GO:0052815=IDA, GO:0006637=IDA, GO:0052817=IDA, GO:0016410=IDA, GO:0052816=IDA, GO:0005782=TAS, GO:0006699=TAS, GO:0019530=IDA, GO:0016290=IEA, GO:0002152=IDA, GO:0031100=IEA, GO:0005102=IPI, GO:0044281=TAS, GO:0005829=TAS, GO:0001889=IEA, GO:0015721=TAS, GO:0006631=IEA, GO:0006544=IDA, GO:0008206=TAS, GO:0047963=IDA} acyl-CoA metabolic process, bile acid and bile salt transport, bile acid biosynthetic process, bile acid conjugation, bile acid metabolic process, fatty acid metabolic process, glycine metabolic process, liver development, organ regeneration, small molecule metabolic process, taurine metabolic process cytosol, peroxisomal matrix N-acyltransferase activity, carboxylesterase activity, glycine N-choloyltransferase activity, long-chain acyl-CoA hydrolase activity, medium-chain acyl-CoA hydrolase activity, palmitoyl-CoA hydrolase activity, receptor binding, very long chain acyl-CoA hydrolase activity Human BABAM1 IntAct UniProtKB {GO:0005515=PMID:22153077, GO:0070531=PMID:19261748, GO:0005737=PMID:19261749, GO:0070552=PMID:19214193, GO:0070536=PMID:19261746, GO:0010212=PMID:19261748, GO:0031572=PMID:19261748, GO:0005634=PMID:19261748, GO:0045739=PMID:19261748, GO:0006302=PMID:19261748, GO:0016568=GO_REF:0000037} Q9NWV8 BRISC and BRCA1-A complex member 1 protein 20130415 {GO:0005515=IPI, GO:0070531=IDA, GO:0005737=IDA, GO:0070552=IDA, GO:0070536=IMP, GO:0010212=IMP, GO:0031572=IMP, GO:0005634=IDA, GO:0045739=IMP, GO:0006302=IMP, GO:0016568=IEA} G2 DNA damage checkpoint, chromatin modification, double-strand break repair, positive regulation of DNA repair, protein K63-linked deubiquitination, response to ionizing radiation BRCA1-A complex, BRISC complex, cytoplasm, nucleus protein binding Human UniProtKB:Q9H2K2 BACE1 PINC UniProtKB {GO:0008798=PMID:10591214, GO:0005802=PMID:11466313, GO:0030424=GO_REF:0000019, GO:0005794=PMID:12586838, GO:0009986=GO_REF:0000039, GO:0005783=GO_REF:0000039, GO:0050435=PMID:15080893, GO:0005887=PMID:12586838, GO:0006508=PMID:10531052, GO:0004190=PMID:10531052, GO:0006509=PMID:12354787, GO:0016021=PMID:10531052, GO:0019899=PMID:12586838, GO:0030659=GO_REF:0000039, GO:0005768=PMID:10531052} P56817 Beta-secretase 1 protein 20030904 {GO:0008798=TAS, GO:0005802=IDA, GO:0030424=IEA, GO:0005794=IDA, GO:0009986=IEA, GO:0005783=IEA, GO:0050435=IDA, GO:0005887=IDA, GO:0006508=IDA, GO:0004190=IDA, GO:0006509=TAS, GO:0016021=NAS, GO:0019899=IPI, GO:0030659=IEA, GO:0005768=IDA} beta-amyloid metabolic process, membrane protein ectodomain proteolysis, proteolysis Golgi apparatus, axon, cell surface, cytoplasmic vesicle membrane, endoplasmic reticulum, endosome, integral to membrane, integral to plasma membrane, trans-Golgi network aspartic-type endopeptidase activity, beta-aspartyl-peptidase activity, enzyme binding Human BACE2 UniProtKB UniProtKB {GO:0005794=PMID:11423558, GO:0016486=PMID:10749877, GO:0009986=GO_REF:0000039, GO:0005783=GO_REF:0000039, GO:0006508=PMID:10749877, GO:0006509=PMID:10591213, GO:0004190=PMID:10591213, GO:0016021=PMID:10749877, GO:0042985=PMID:12801932, GO:0005768=GO_REF:0000039} Q9Y5Z0 Beta-secretase 2 protein 20040526 {GO:0005794=IDA, GO:0016486=NAS, GO:0009986=IEA, GO:0005783=IEA, GO:0006508=NAS, GO:0006509=IDA, GO:0004190=IDA, GO:0016021=NAS, GO:0042985=IMP, GO:0005768=IEA} membrane protein ectodomain proteolysis, negative regulation of amyloid precursor protein biosynthetic process, peptide hormone processing, proteolysis Golgi apparatus, cell surface, endoplasmic reticulum, endosome, integral to membrane aspartic-type endopeptidase activity Human BACH1 UniProtKB UniProtKB {GO:0000117=PMID:21555518, GO:0043565=GO_REF:0000002, GO:0001078=PMID:12511571, GO:0006355=GO_REF:0000024, GO:0000083=PMID:21555518, GO:0003700=GO_REF:0000024, GO:0061418=PMID:12511571, GO:0005634=PMID:12511571, GO:0000122=PMID:21555518, GO:0003677=GO_REF:0000019, GO:0020037=PMID:21555518, GO:0005829=PMID:16780588} O14867 Transcription regulator protein BACH1 protein 20110831 {GO:0000117=IMP, GO:0043565=IEA, GO:0001078=IDA, GO:0006355=ISS, GO:0000083=IMP, GO:0003700=ISS, GO:0061418=IDA, GO:0005634=IDA, GO:0000122=IMP, GO:0003677=IEA, GO:0020037=NAS, GO:0005829=IDA} negative regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter in response to hypoxia, regulation of transcription involved in G1/S phase of mitotic cell cycle, regulation of transcription involved in G2/M-phase of mitotic cell cycle, regulation of transcription, DNA-dependent cytosol, nucleus DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, heme binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human BACH2 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q9BYV9 Transcription regulator protein BACH2 protein 20130413 {GO:0043565=IEA, GO:0003700=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0191 BAD HPA UniProtKB {GO:0005515=PMID:20603619, GO:0042542=GO_REF:0000019, GO:0030346=GO_REF:0000019, GO:0019221=GO_REF:0000019, GO:0097202=PMID:18387192, GO:0071396=GO_REF:0000019, GO:1900740=Reactome:REACT_697, GO:0007173=Reactome:REACT_9417, GO:0032024=GO_REF:0000024, GO:0032355=GO_REF:0000019, GO:0050679=PMID:19593445, GO:0046034=GO_REF:0000024, GO:0046982=GO_REF:0000019, GO:0019901=PMID:17270021, GO:0046031=GO_REF:0000024, GO:2001244=Reactome:REACT_330, GO:0051384=GO_REF:0000019, GO:0071316=PMID:18676776, GO:0008656=PMID:18402937, GO:0043280=PMID:18402937, GO:0046931=PMID:21081150, GO:0051592=GO_REF:0000019, GO:0071247=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:2000078=GO_REF:0000024, GO:0032570=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0045579=GO_REF:0000019, GO:0005741=Reactome:REACT_21278, GO:0005829=Reactome:REACT_147775, GO:0008289=PMID:19667065, GO:0005739=GO_REF:0000052, GO:0005543=PMID:21081150, GO:0044342=GO_REF:0000024, GO:0006007=GO_REF:0000019, GO:0043200=GO_REF:0000019, GO:0045582=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0046902=PMID:20700721, GO:0048011=Reactome:REACT_13776, GO:0043065=PMID:9388232, GO:0035774=GO_REF:0000019, GO:0006919=GO_REF:0000024, GO:0048015=Reactome:REACT_12464, GO:0042493=GO_REF:0000019, GO:0034201=GO_REF:0000019, GO:0006915=Reactome:REACT_13638, GO:0071456=PMID:20810912, GO:0033133=GO_REF:0000024, GO:0042593=GO_REF:0000024, GO:0006917=PMID:19667065, GO:0033574=GO_REF:0000019, GO:0097191=PMID:18852119, GO:0043422=GO_REF:0000019, GO:0097190=Reactome:REACT_13720, GO:0045862=PMID:18387192, GO:0097193=Reactome:REACT_964, GO:0009749=GO_REF:0000019, GO:0010918=GO_REF:0000024, GO:0060154=GO_REF:0000019, GO:0071260=PMID:19593445} Q92934 Bcl2 antagonist of cell death protein 20101115 {GO:0005515=IPI, GO:0042542=IEA, GO:0030346=IEA, GO:0019221=IEA, GO:0097202=IDA, GO:0071396=IEA, GO:1900740=TAS, GO:0007173=TAS, GO:0032024=ISS, GO:0032355=IEA, GO:0050679=IMP, GO:0046034=ISS, GO:0046982=IEA, GO:0019901=IPI, GO:0046031=ISS, GO:2001244=TAS, GO:0051384=IEA, GO:0071316=IDA, GO:0008656=IDA, GO:0043280=IDA, GO:0046931=IDA, GO:0051592=IEA, GO:0071247=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:2000078=ISS, GO:0032570=IEA, GO:0045471=IEA, GO:0045579=IEA, GO:0005741=TAS, GO:0005829=TAS, GO:0008289=IDA, GO:0005739=IDA, GO:0005543=IMP, GO:0044342=ISS, GO:0006007=IEA, GO:0043200=IEA, GO:0045582=IEA, GO:0001666=IEA, GO:0046902=IMP, GO:0048011=TAS, GO:0043065=IDA, GO:0035774=IEA, GO:0006919=ISS, GO:0048015=TAS, GO:0042493=IEA, GO:0034201=IEA, GO:0006915=TAS, GO:0071456=IEP, GO:0033133=ISS, GO:0042593=ISS, GO:0006917=IDA, GO:0033574=IEA, GO:0097191=IMP, GO:0043422=IEA, GO:0097190=TAS, GO:0045862=IDA, GO:0097193=TAS, GO:0009749=IEA, GO:0010918=ISS, GO:0060154=IEA, GO:0071260=IEP} ADP metabolic process, ATP metabolic process, activation of cysteine-type endopeptidase activity, activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, apoptotic signaling pathway, cellular process regulating host cell cycle in response to virus, cellular response to chromate, cellular response to hypoxia, cellular response to lipid, cellular response to mechanical stimulus, cellular response to nicotine, cytokine-mediated signaling pathway, epidermal growth factor receptor signaling pathway, extrinsic apoptotic signaling pathway, fibroblast growth factor receptor signaling pathway, glucose catabolic process, glucose homeostasis, induction of apoptosis, innate immune response, intrinsic apoptotic signaling pathway, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, pore complex assembly, positive regulation of B cell differentiation, positive regulation of T cell differentiation, positive regulation of apoptotic process, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of epithelial cell proliferation, positive regulation of glucokinase activity, positive regulation of insulin secretion, positive regulation of insulin secretion involved in cellular response to glucose stimulus, positive regulation of intrinsic apoptotic signaling pathway, positive regulation of mitochondrial membrane potential, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, positive regulation of proteolysis, positive regulation of type B pancreatic cell development, regulation of mitochondrial membrane permeability, response to amino acid stimulus, response to calcium ion, response to drug, response to estradiol stimulus, response to ethanol, response to glucocorticoid stimulus, response to glucose stimulus, response to hydrogen peroxide, response to hypoxia, response to oleic acid, response to progesterone stimulus, response to testosterone stimulus, type B pancreatic cell proliferation cytosol, mitochondrial outer membrane, mitochondrion cysteine-type endopeptidase activator activity involved in apoptotic process, lipid binding, phospholipid binding, protein binding, protein heterodimerization activity, protein kinase B binding, protein kinase binding, protein phosphatase 2B binding Human BAG1 LIFEdb UniProtKB {GO:0051219=GO_REF:0000019, GO:0005515=PMID:9305631, GO:0043066=PMID:8947043, GO:0051087=GO_REF:0000002, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000054, GO:0005829=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0043525=GO_REF:0000019, GO:0070389=PMID:12853476, GO:0030182=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0005057=PMID:8947043, GO:0007166=PMID:8947043} Q99933 BAG family molecular chaperone regulator 1 protein 20100607 {GO:0051219=IEA, GO:0005515=IPI, GO:0043066=TAS, GO:0051087=IEA, GO:0006915=IEA, GO:0005634=IDA, GO:0005829=IEA, GO:0005737=IEA, GO:0043525=IEA, GO:0070389=IDA, GO:0030182=IEA, GO:0045944=IEA, GO:0005057=TAS, GO:0007166=TAS} apoptotic process, cell surface receptor signaling pathway, chaperone cofactor-dependent protein refolding, negative regulation of apoptotic process, neuron differentiation, positive regulation of neuron apoptotic process, positive regulation of transcription from RNA polymerase II promoter cytoplasm, cytosol, nucleus chaperone binding, phosphoprotein binding, protein binding, receptor signaling protein activity Human BAG2 MGI UniProtKB {GO:0006457=PMID:9873016, GO:0051087=GO_REF:0000002, GO:0019538=PMID:9873015} O95816 BAG family molecular chaperone regulator 2 protein 20060110 {GO:0006457=TAS, GO:0051087=IEA, GO:0019538=IDA} protein folding, protein metabolic process chaperone binding Human BAG3 HPA UniProtKB {GO:0005515=PMID:22366786, GO:0043005=GO_REF:0000019, GO:0043066=PMID:10597216, GO:0005737=GO_REF:0000052, GO:0021510=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0006457=PMID:9873016, GO:0007420=GO_REF:0000019, GO:0051087=GO_REF:0000002, GO:0006915=GO_REF:0000037, GO:0032403=GO_REF:0000019, GO:0005829=PMID:10597216} O95817 BAG family molecular chaperone regulator 3 protein 20100326 {GO:0005515=IPI, GO:0043005=IEA, GO:0043066=NAS, GO:0005737=IDA, GO:0021510=IEA, GO:0005886=IDA, GO:0006457=NAS, GO:0007420=IEA, GO:0051087=IEA, GO:0006915=IEA, GO:0032403=IEA, GO:0005829=IDA} apoptotic process, brain development, negative regulation of apoptotic process, protein folding, spinal cord development cytoplasm, cytosol, neuron projection, plasma membrane chaperone binding, protein binding, protein complex binding Human BAG4 HPA UniProtKB {GO:0051897=GO_REF:0000019, GO:0043066=PMID:9915703, GO:2001145=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0051087=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0072659=GO_REF:0000019, GO:0045785=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0033138=GO_REF:0000019, GO:0010763=GO_REF:0000019, GO:0030838=GO_REF:0000019, GO:0006457=PMID:9873016, GO:0071364=GO_REF:0000019, GO:0051496=GO_REF:0000019, GO:0071356=PMID:21712384, GO:0097178=GO_REF:0000019, GO:0005057=PMID:9915703} O95429 BAG family molecular chaperone regulator 4 protein 20100326 {GO:0051897=IEA, GO:0043066=TAS, GO:2001145=IEA, GO:0005730=IDA, GO:0051087=IEA, GO:0005634=IDA, GO:0072659=IEA, GO:0045785=IEA, GO:0005737=IDA, GO:0033138=IEA, GO:0010763=IEA, GO:0030838=IEA, GO:0006457=TAS, GO:0071364=IEA, GO:0051496=IEA, GO:0071356=IDA, GO:0097178=IEA, GO:0005057=TAS} cellular response to epidermal growth factor stimulus, cellular response to tumor necrosis factor, negative regulation of apoptotic process, negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity, positive regulation of actin filament polymerization, positive regulation of cell adhesion, positive regulation of fibroblast migration, positive regulation of peptidyl-serine phosphorylation, positive regulation of protein kinase B signaling cascade, positive regulation of stress fiber assembly, protein folding, protein localization to plasma membrane, ruffle assembly cytoplasm, nucleolus, nucleus chaperone binding, receptor signaling protein activity Human BAG5 BHF-UCL UniProtKB {GO:0090083=PMID:15603737, GO:0048471=PMID:15603737, GO:0016234=PMID:15603737, GO:0006457=PMID:9873016, GO:0070997=PMID:15603737, GO:0051087=PMID:15603737, GO:0061084=PMID:15603737, GO:0051444=PMID:15603737, GO:0031397=PMID:15603737, GO:0031625=PMID:15603737} Q9UL15 BAG family molecular chaperone regulator 5 protein 20100429 {GO:0090083=IMP, GO:0048471=IDA, GO:0016234=IDA, GO:0006457=TAS, GO:0070997=ISS, GO:0051087=IPI, GO:0061084=ISS, GO:0051444=ISS, GO:0031397=ISS, GO:0031625=ISS} negative regulation of protein refolding, negative regulation of protein ubiquitination, negative regulation of ubiquitin-protein ligase activity, neuron death, protein folding, regulation of inclusion body assembly inclusion body, perinuclear region of cytoplasm chaperone binding, ubiquitin protein ligase binding Human UniProtKB:Q5QJC9 BAG6 IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0006511=GO_REF:0000024, GO:0030324=GO_REF:0000024, GO:0005634=PMID:17403783, GO:0032435=GO_REF:0000024, GO:0009790=GO_REF:0000024, GO:0007283=GO_REF:0000024, GO:0030154=GO_REF:0000037, GO:0005829=PMID:17403783, GO:0005737=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0006810=GO_REF:0000037, GO:0007130=GO_REF:0000024, GO:0001822=GO_REF:0000024, GO:0050821=GO_REF:0000024, GO:0045861=GO_REF:0000024, GO:0018393=PMID:17403783, GO:0042771=PMID:17403783, GO:0007420=GO_REF:0000024, GO:0070059=GO_REF:0000024, GO:0070628=GO_REF:0000024, GO:0030544=GO_REF:0000019, GO:0043022=PMID:20676083, GO:0071816=PMID:20676083, GO:0071818=PMID:20676083, GO:0031593=GO_REF:0000024, GO:0016568=GO_REF:0000037} P46379 Large proline-rich protein BAG6 protein 20130415 {GO:0005515=IPI, GO:0006511=ISS, GO:0030324=ISS, GO:0005634=IDA, GO:0032435=ISS, GO:0009790=ISS, GO:0007283=ISS, GO:0030154=IEA, GO:0005829=IDA, GO:0005737=IEA, GO:0042127=IEA, GO:0006810=IEA, GO:0007130=ISS, GO:0001822=ISS, GO:0050821=ISS, GO:0045861=ISS, GO:0018393=IDA, GO:0042771=IMP, GO:0007420=ISS, GO:0070059=ISS, GO:0070628=ISS, GO:0030544=IEA, GO:0043022=IDA, GO:0071816=IDA, GO:0071818=IDA, GO:0031593=ISS, GO:0016568=IEA} brain development, cell differentiation, chromatin modification, embryo development, internal peptidyl-lysine acetylation, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, kidney development, lung development, negative regulation of proteasomal ubiquitin-dependent protein catabolic process, negative regulation of proteolysis, protein stabilization, regulation of cell proliferation, spermatogenesis, synaptonemal complex assembly, tail-anchored membrane protein insertion into ER membrane, transport, ubiquitin-dependent protein catabolic process BAT3 complex, cytoplasm, cytosol, nucleus Hsp70 protein binding, polyubiquitin binding, proteasome binding, protein binding, ribosome binding Human UniProtKB:Q7Z434 BAGE3 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q86Y29 B melanoma antigen 3 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 BAHCC1 InterPro UniProtKB {GO:0003677=GO_REF:0000002} Q9P281 BAH and coiled-coil domain-containing protein 1 protein 20130413 {GO:0003677=IEA} DNA binding Human InterPro:IPR001025 BAHD1 UniProtKB UniProtKB {GO:0005515=PMID:19666599, GO:0031507=PMID:19666599, GO:0005694=GO_REF:0000039, GO:0003682=PMID:19666599, GO:0045892=PMID:19666599, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0005677=PMID:19666599} Q8TBE0 Bromo adjacent homology domain-containing 1 protein protein 20091029 {GO:0005515=IPI, GO:0031507=IMP, GO:0005694=IEA, GO:0003682=IDA, GO:0045892=IMP, GO:0003677=IEA, GO:0006351=IEA, GO:0005677=IDA} heterochromatin assembly, negative regulation of transcription, DNA-dependent, transcription, DNA-dependent chromatin silencing complex, chromosome DNA binding, chromatin binding, protein binding Human BAI1 GDB UniProtKB {GO:0008285=PMID:7531056, GO:0005886=PMID:9647739, GO:0004930=GO_REF:0000037, GO:0007409=PMID:10343108, GO:0007165=PMID:9647739, GO:0007186=PMID:15203201, GO:0007218=GO_REF:0000002, GO:0005887=PMID:9647739, GO:0005911=PMID:9647739, GO:0016525=GO_REF:0000002, GO:0007422=PMID:10343108, GO:0016021=PMID:15203201, GO:0007155=GO_REF:0000037} O14514 Brain-specific angiogenesis inhibitor 1 protein 20050509 {GO:0008285=TAS, GO:0005886=TAS, GO:0004930=IEA, GO:0007409=TAS, GO:0007165=TAS, GO:0007186=TAS, GO:0007218=IEA, GO:0005887=TAS, GO:0005911=TAS, GO:0016525=IEA, GO:0007422=TAS, GO:0016021=TAS, GO:0007155=IEA} G-protein coupled receptor signaling pathway, axonogenesis, cell adhesion, negative regulation of angiogenesis, negative regulation of cell proliferation, neuropeptide signaling pathway, peripheral nervous system development, signal transduction cell-cell junction, integral to membrane, integral to plasma membrane, plasma membrane G-protein coupled receptor activity Human BAI2 GDB UniProtKB {GO:0007186=PMID:15203201, GO:0016020=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0007218=GO_REF:0000002, GO:0004930=GO_REF:0000037, GO:0007422=GO_REF:0000019, GO:0016525=GO_REF:0000002, GO:0016021=GO_REF:0000037} O60241 Brain-specific angiogenesis inhibitor 2 protein 20050509 {GO:0007186=TAS, GO:0016020=IEA, GO:0005886=IEA, GO:0007218=IEA, GO:0004930=IEA, GO:0007422=IEA, GO:0016525=IEA, GO:0016021=IEA} G-protein coupled receptor signaling pathway, negative regulation of angiogenesis, neuropeptide signaling pathway, peripheral nervous system development integral to membrane, membrane, plasma membrane G-protein coupled receptor activity Human BAI3 GDB UniProtKB {GO:0007186=PMID:15203201, GO:0005886=GO_REF:0000039, GO:0007218=GO_REF:0000002, GO:0004930=GO_REF:0000037, GO:0016525=GO_REF:0000002, GO:0016021=GO_REF:0000037} O60242 Brain-specific angiogenesis inhibitor 3 protein 20050509 {GO:0007186=TAS, GO:0005886=IEA, GO:0007218=IEA, GO:0004930=IEA, GO:0016525=IEA, GO:0016021=IEA} G-protein coupled receptor signaling pathway, negative regulation of angiogenesis, neuropeptide signaling pathway integral to membrane, plasma membrane G-protein coupled receptor activity Human BAIAP2 HPA UniProtKB {GO:0008286=PMID:10343108, GO:0005515=PMID:19171758, GO:0043005=GO_REF:0000019, GO:0017124=GO_REF:0000002, GO:0030054=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0008360=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0030175=GO_REF:0000039, GO:0007409=PMID:10343108, GO:0015629=PMID:19366662, GO:0042802=PMID:14752106, GO:0005829=Reactome:REACT_160291, GO:0009617=PMID:19366662, GO:0005737=GO_REF:0000052, GO:0048167=GO_REF:0000019, GO:0032956=PMID:19366662, GO:0046847=GO_REF:0000002, GO:0051764=GO_REF:0000024, GO:0051017=GO_REF:0000024, GO:0070064=PMID:19366662, GO:0008093=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0008022=PMID:10343108, GO:0001726=GO_REF:0000039, GO:0016358=GO_REF:0000019, GO:0007165=GO_REF:0000002, GO:0045087=Reactome:REACT_6802, GO:0038096=Reactome:REACT_160123} Q9UQB8 Brain-specific angiogenesis inhibitor 1-associated protein 2 protein 20101115 {GO:0008286=TAS, GO:0005515=IPI, GO:0043005=IEA, GO:0017124=IEA, GO:0030054=IDA, GO:0005886=IDA, GO:0008360=ISS, GO:0005634=IDA, GO:0030175=IEA, GO:0007409=TAS, GO:0015629=IDA, GO:0042802=IPI, GO:0005829=TAS, GO:0009617=IMP, GO:0005737=IDA, GO:0048167=IEA, GO:0032956=IMP, GO:0046847=IEA, GO:0051764=ISS, GO:0051017=ISS, GO:0070064=IDA, GO:0008093=IEA, GO:0005730=IDA, GO:0008022=TAS, GO:0001726=IEA, GO:0016358=IEA, GO:0007165=IEA, GO:0045087=TAS, GO:0038096=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, actin crosslink formation, actin filament bundle assembly, axonogenesis, dendrite development, filopodium assembly, innate immune response, insulin receptor signaling pathway, regulation of actin cytoskeleton organization, regulation of cell shape, regulation of synaptic plasticity, response to bacterium, signal transduction actin cytoskeleton, cell junction, cytoplasm, cytosol, filopodium, neuron projection, nucleolus, nucleus, plasma membrane, ruffle SH3 domain binding, cytoskeletal adaptor activity, identical protein binding, proline-rich region binding, protein C-terminus binding, protein binding Human BAIAP2L1 HPA UniProtKB {GO:0017124=GO_REF:0000002, GO:0030054=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:2000251=PMID:19366662, GO:0003779=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0015629=PMID:19366662, GO:0005829=PMID:19366662, GO:0007165=GO_REF:0000002, GO:0009617=PMID:19366662, GO:0005737=GO_REF:0000052, GO:0030838=PMID:21098279, GO:0046847=GO_REF:0000002, GO:0070064=PMID:21098279, GO:0008093=GO_REF:0000002} Q9UHR4 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 protein 20090616 {GO:0017124=IEA, GO:0030054=IDA, GO:0005886=IDA, GO:0005730=IDA, GO:2000251=IMP, GO:0003779=IEA, GO:0005634=IDA, GO:0015629=IDA, GO:0005829=IDA, GO:0007165=IEA, GO:0009617=IDA, GO:0005737=IDA, GO:0030838=IDA, GO:0046847=IEA, GO:0070064=IDA, GO:0008093=IEA} filopodium assembly, positive regulation of actin cytoskeleton reorganization, positive regulation of actin filament polymerization, response to bacterium, signal transduction actin cytoskeleton, cell junction, cytoplasm, cytosol, nucleolus, nucleus, plasma membrane SH3 domain binding, actin binding, cytoskeletal adaptor activity, proline-rich region binding Human BAIAP2L2 InterPro UniProtKB {GO:0012506=PMID:21743456, GO:0007165=GO_REF:0000002, GO:0017124=GO_REF:0000002, GO:0005543=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0071439=PMID:21401524, GO:0044291=PMID:21743456, GO:0046847=GO_REF:0000002, GO:0016044=GO_REF:0000024, GO:0030659=GO_REF:0000039, GO:0008093=GO_REF:0000002} Q9H661 BAI1-associated protein 2-like 2, isoform CRA_b protein 20130413 {GO:0012506=IDA, GO:0007165=IEA, GO:0017124=IEA, GO:0005543=ISS, GO:0005886=IEA, GO:0071439=IDA, GO:0044291=IDA, GO:0046847=IEA, GO:0016044=ISS, GO:0030659=IEA, GO:0008093=IEA} cellular membrane organization, filopodium assembly, signal transduction cell-cell contact zone, clathrin complex, cytoplasmic vesicle membrane, plasma membrane, vesicle membrane SH3 domain binding, cytoskeletal adaptor activity, phospholipid binding Human InterPro:IPR013606 BAIAP3 MGI UniProtKB {GO:0007186=PMID:9790924, GO:0008022=PMID:9790924, GO:0007269=PMID:9790924} O94812 BAI1-associated protein 3 protein 20091111 {GO:0007186=IPI, GO:0008022=TAS, GO:0007269=TAS} G-protein coupled receptor signaling pathway, neurotransmitter secretion protein C-terminus binding Human UniProtKB:O14514 BAK1 BHF-UCL UniProtKB {GO:0005515=PMID:10950869, GO:0043496=PMID:9111042, GO:0014070=GO_REF:0000019, GO:0042542=GO_REF:0000019, GO:0043497=PMID:9111042, GO:0051400=GO_REF:0000019, GO:0010524=GO_REF:0000019, GO:0097202=PMID:18387192, GO:0042803=GO_REF:0000019, GO:0042802=PMID:21041309, GO:0048597=GO_REF:0000019, GO:0034644=GO_REF:0000024, GO:0008053=GO_REF:0000019, GO:0031072=GO_REF:0000019, GO:0002262=GO_REF:0000019, GO:0010332=GO_REF:0000019, GO:0046982=PMID:10837489, GO:0007568=GO_REF:0000019, GO:0010248=PMID:9843949, GO:0046930=PMID:9843949, GO:0010046=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0070059=GO_REF:0000019, GO:0031307=GO_REF:0000024, GO:0032471=GO_REF:0000019, GO:0001783=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0001782=GO_REF:0000019, GO:0005783=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0031100=GO_REF:0000019, GO:0060068=GO_REF:0000019, GO:0009620=GO_REF:0000019, GO:0051087=GO_REF:0000019, GO:0005741=Reactome:REACT_6153, GO:0001836=PMID:21041309, GO:0046872=GO_REF:0000037, GO:0005829=GO_REF:0000019, GO:0005739=PMID:9843949, GO:0033137=GO_REF:0000019, GO:0090200=GO_REF:0000019, GO:0051726=GO_REF:0000019, GO:0035108=GO_REF:0000019, GO:0046902=PMID:21041309, GO:0008635=GO_REF:0000019, GO:0043065=PMID:17289999, GO:1901030=Reactome:REACT_707, GO:0042493=GO_REF:0000019, GO:0051881=PMID:9843949, GO:0006915=Reactome:REACT_578, GO:0097190=PMID:15901672, GO:0045862=PMID:18387192, GO:0097193=Reactome:REACT_964, GO:0010225=GO_REF:0000019, GO:0001974=GO_REF:0000019, GO:0031018=GO_REF:0000019, GO:0010629=GO_REF:0000019, GO:0002352=GO_REF:0000019, GO:0071260=PMID:19593445} Q16611 Bcl-2 homologous antagonist/killer protein 20120404 {GO:0005515=IPI, GO:0043496=IDA, GO:0014070=IEA, GO:0042542=IEA, GO:0043497=IDA, GO:0051400=IEA, GO:0010524=IEA, GO:0097202=IDA, GO:0042803=IEA, GO:0042802=IPI, GO:0048597=IEA, GO:0034644=ISS, GO:0008053=IEA, GO:0031072=IEA, GO:0002262=IEA, GO:0010332=IEA, GO:0046982=IPI, GO:0007568=IEA, GO:0010248=IDA, GO:0046930=IDA, GO:0010046=IEA, GO:0007420=IEA, GO:0070059=IEA, GO:0031307=ISS, GO:0032471=IEA, GO:0001783=IEA, GO:0008285=IEA, GO:0001782=IEA, GO:0005783=IEA, GO:0008283=IEA, GO:0045471=IEA, GO:0031100=IEA, GO:0060068=IEA, GO:0009620=IEA, GO:0051087=IEA, GO:0005741=TAS, GO:0001836=IGI, GO:0046872=IEA, GO:0005829=IEA, GO:0005739=IDA, GO:0033137=IEA, GO:0090200=IEA, GO:0051726=IEA, GO:0035108=IEA, GO:0046902=IDA, GO:0008635=IEA, GO:0043065=IMP, GO:1901030=TAS, GO:0042493=IEA, GO:0051881=IDA, GO:0006915=TAS, GO:0097190=IMP, GO:0045862=IDA, GO:0097193=TAS, GO:0010225=IEA, GO:0001974=IEA, GO:0031018=IEA, GO:0010629=IEA, GO:0002352=IEA, GO:0071260=IEP} B cell apoptotic process, B cell homeostasis, B cell negative selection, activation of cysteine-type endopeptidase activity, activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c, aging, apoptotic process, apoptotic signaling pathway, blood vessel remodeling, brain development, cell proliferation, cellular response to UV, cellular response to mechanical stimulus, endocrine pancreas development, establishment or maintenance of transmembrane electrochemical gradient, intrinsic apoptotic signaling pathway, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, limb morphogenesis, mitochondrial fusion, myeloid cell homeostasis, negative regulation of cell proliferation, negative regulation of gene expression, negative regulation of peptidyl-serine phosphorylation, organ regeneration, positive regulation of apoptotic process, positive regulation of calcium ion transport into cytosol, positive regulation of mitochondrial outer membrane permeabilization, positive regulation of proteolysis, positive regulation of release of cytochrome c from mitochondria, post-embryonic camera-type eye morphogenesis, reduction of endoplasmic reticulum calcium ion concentration, regulation of cell cycle, regulation of mitochondrial membrane permeability, regulation of mitochondrial membrane potential, regulation of protein heterodimerization activity, regulation of protein homodimerization activity, release of cytochrome c from mitochondria, response to UV-C, response to drug, response to ethanol, response to fungus, response to gamma radiation, response to hydrogen peroxide, response to mycotoxin, response to organic cyclic compound, vagina development cytosol, endoplasmic reticulum, integral to mitochondrial outer membrane, mitochondrial outer membrane, mitochondrion, pore complex BH domain binding, chaperone binding, heat shock protein binding, identical protein binding, metal ion binding, protein binding, protein heterodimerization activity, protein homodimerization activity Human BAMBI BHF-UCL UniProtKB {GO:0008284=PMID:18838381, GO:0005886=PMID:18756595, GO:0008360=PMID:19328798, GO:0090263=PMID:18838381, GO:0010718=PMID:19328798, GO:0035413=PMID:18838381, GO:0032092=PMID:18838381, GO:0005114=PMID:18756595, GO:0005109=PMID:18838381, GO:0005737=PMID:18756595, GO:0016477=PMID:19328798, GO:0007179=Reactome:REACT_120850, GO:0016021=GO_REF:0000037, GO:0045893=PMID:18838381, GO:0030512=PMID:19328798} Q13145 BMP and activin membrane-bound inhibitor homolog protein 20100903 {GO:0008284=IMP, GO:0005886=IDA, GO:0008360=IMP, GO:0090263=IDA, GO:0010718=IMP, GO:0035413=IMP, GO:0032092=IMP, GO:0005114=TAS, GO:0005109=IPI, GO:0005737=IDA, GO:0016477=IDA, GO:0007179=TAS, GO:0016021=IEA, GO:0045893=IDA, GO:0030512=IMP} cell migration, negative regulation of transforming growth factor beta receptor signaling pathway, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of catenin import into nucleus, positive regulation of cell proliferation, positive regulation of epithelial to mesenchymal transition, positive regulation of protein binding, positive regulation of transcription, DNA-dependent, regulation of cell shape, transforming growth factor beta receptor signaling pathway cytoplasm, integral to membrane, plasma membrane frizzled binding, type II transforming growth factor beta receptor binding Human BANF1 Reactome UniProtKB {GO:0005515=PMID:22770216, GO:0007077=Reactome:REACT_160255, GO:0022415=Reactome:REACT_6266, GO:0005694=GO_REF:0000039, GO:0007084=Reactome:REACT_160113, GO:0015074=GO_REF:0000019, GO:0009615=PMID:9465049, GO:0003677=GO_REF:0000037, GO:0005829=Reactome:REACT_160246, GO:0000088=Reactome:REACT_765, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6256, GO:0005654=Reactome:REACT_160221, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0075713=Reactome:REACT_8990} O75531 Barrier-to-autointegration factor protein 20130121 {GO:0005515=IPI, GO:0007077=TAS, GO:0022415=TAS, GO:0005694=IEA, GO:0007084=TAS, GO:0015074=IEA, GO:0009615=TAS, GO:0003677=IEA, GO:0005829=TAS, GO:0000088=TAS, GO:0000087=TAS, GO:0016032=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0075713=TAS} DNA integration, M phase of mitotic cell cycle, establishment of integrated proviral latency, mitotic anaphase, mitotic cell cycle, mitotic nuclear envelope disassembly, mitotic nuclear envelope reassembly, mitotic prophase, response to virus, viral reproduction, viral reproductive process chromosome, cytosol, nucleoplasm DNA binding, protein binding Human BANK1 UniProtKB UniProtKB {GO:0042113=GO_REF:0000037} Q8NDB2 B-cell scaffold protein with ankyrin repeats protein 20130413 {GO:0042113=IEA} B cell activation Human UniProtKB-KW:KW-0075 BANP UniProtKB UniProtKB {GO:0002039=GO_REF:0000019, GO:0007049=GO_REF:0000037, GO:0006355=GO_REF:0000037, GO:0034504=GO_REF:0000019, GO:0042177=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q8N9N5 Protein BANP protein 20130413 {GO:0002039=IEA, GO:0007049=IEA, GO:0006355=IEA, GO:0034504=IEA, GO:0042177=IEA, GO:0007275=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0016568=IEA} cell cycle, chromatin modification, multicellular organismal development, negative regulation of protein catabolic process, protein localization to nucleus, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, p53 binding Human UniProtKB-SubCell:SL-0191 BAP1 HPA UniProtKB {GO:0005515=PMID:22897849, GO:0071108=PMID:19188440, GO:0006511=GO_REF:0000002, GO:0016579=PMID:18757409, GO:0008285=PMID:9528852, GO:0004843=PMID:18757409, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0001558=PMID:19815555, GO:0035517=PMID:20436459, GO:0043231=GO_REF:0000052, GO:0005622=GO_REF:0000002, GO:0005737=PMID:19188440, GO:0035522=PMID:20436459, GO:0003682=PMID:19815555, GO:0051726=PMID:19188440, GO:0008233=PMID:9528852, GO:0004221=PMID:19815555, GO:0006464=PMID:9528852} Q92560 Ubiquitin carboxyl-terminal hydrolase BAP1 protein 20120912 {GO:0005515=IPI, GO:0071108=IMP, GO:0006511=IEA, GO:0016579=IDA, GO:0008285=TAS, GO:0004843=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0001558=IMP, GO:0035517=IDA, GO:0043231=IDA, GO:0005622=IEA, GO:0005737=IDA, GO:0035522=IDA, GO:0003682=IDA, GO:0051726=IMP, GO:0008233=NAS, GO:0004221=IMP, GO:0006464=NAS} cellular protein modification process, monoubiquitinated histone H2A deubiquitination, negative regulation of cell proliferation, protein K48-linked deubiquitination, protein deubiquitination, regulation of cell cycle, regulation of cell growth, ubiquitin-dependent protein catabolic process PR-DUB complex, cytoplasm, intracellular, intracellular membrane-bounded organelle, nucleolus, nucleus chromatin binding, peptidase activity, protein binding, ubiquitin thiolesterase activity, ubiquitin-specific protease activity Human BARD1 IntAct UniProtKB {GO:0005515=PMID:15383276, GO:0085020=PMID:12890688, GO:0043066=PMID:15265711, GO:0045732=PMID:15905410, GO:0004842=PMID:20351172, GO:0043065=PMID:15782130, GO:0016567=PMID:15905410, GO:0046982=PMID:15265711, GO:0003723=PMID:12419249, GO:0000151=PMID:14976165, GO:0005634=PMID:15632137, GO:0031436=PMID:19117993, GO:0042803=PMID:15265711, GO:0006974=PMID:15905410, GO:0070531=PMID:19261749, GO:0042325=PMID:15782130, GO:0046826=PMID:15265711, GO:0005737=PMID:15265711, GO:0006281=GO_REF:0000037, GO:0001894=PMID:15782130, GO:0007050=PMID:15632137, GO:0008270=GO_REF:0000002, GO:0019900=PMID:15782130, GO:0031441=PMID:15905410} Q99728 BRCA1-associated RING domain protein 1 protein 20130415 {GO:0005515=IPI, GO:0085020=IDA, GO:0043066=IMP, GO:0045732=NAS, GO:0004842=IDA, GO:0043065=IMP, GO:0016567=NAS, GO:0046982=IPI, GO:0003723=IDA, GO:0000151=NAS, GO:0005634=IMP, GO:0031436=IDA, GO:0042803=IPI, GO:0006974=NAS, GO:0070531=IDA, GO:0042325=IMP, GO:0046826=IDA, GO:0005737=IDA, GO:0006281=IEA, GO:0001894=TAS, GO:0007050=NAS, GO:0008270=IEA, GO:0019900=NAS, GO:0031441=NAS} DNA repair, cell cycle arrest, negative regulation of apoptotic process, negative regulation of mRNA 3'-end processing, negative regulation of protein export from nucleus, positive regulation of apoptotic process, positive regulation of protein catabolic process, protein K6-linked ubiquitination, protein ubiquitination, regulation of phosphorylation, response to DNA damage stimulus, tissue homeostasis BRCA1-A complex, BRCA1-BARD1 complex, cytoplasm, nucleus, ubiquitin ligase complex RNA binding, kinase binding, protein binding, protein heterodimerization activity, protein homodimerization activity, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q9Y2X7 BARHL1 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0043524=GO_REF:0000019, GO:0001077=GO_REF:0000019, GO:0007605=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0030901=GO_REF:0000019, GO:0001764=GO_REF:0000019} Q9BZE3 BarH-like 1 homeobox protein protein 20130413 {GO:0043565=IEA, GO:0043524=IEA, GO:0001077=IEA, GO:0007605=IEA, GO:0005634=IEA, GO:0030901=IEA, GO:0001764=IEA} midbrain development, negative regulation of neuron apoptotic process, neuron migration, sensory perception of sound nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, sequence-specific DNA binding Human UniProtKB-SubCell:SL-0191 BARX1 UniProtKB UniProtKB {GO:0055123=GO_REF:0000019, GO:0006355=GO_REF:0000029, GO:0000976=GO_REF:0000002, GO:0003700=PMID:10995576, GO:0030855=GO_REF:0000019, GO:0030178=GO_REF:0000019, GO:0007267=GO_REF:0000019, GO:0007275=GO_REF:0000029, GO:0000228=GO_REF:0000029, GO:0048536=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q9HBU1 Homeobox protein BarH-like 1 protein 20021104 {GO:0055123=IEA, GO:0006355=NAS, GO:0000976=IEA, GO:0003700=NAS, GO:0030855=IEA, GO:0030178=IEA, GO:0007267=IEA, GO:0007275=NAS, GO:0000228=NAS, GO:0048536=IEA, GO:0009952=IEA, GO:0006351=IEA} anterior/posterior pattern specification, cell-cell signaling, digestive system development, epithelial cell differentiation, multicellular organismal development, negative regulation of Wnt receptor signaling pathway, regulation of transcription, DNA-dependent, spleen development, transcription, DNA-dependent nuclear chromosome sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding Human BARX2 MGI UniProtKB {GO:0005667=GO_REF:0000019, GO:0014902=GO_REF:0000019, GO:0000976=GO_REF:0000002, GO:0003700=GO_REF:0000019, GO:0001502=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0005634=GO_REF:0000040, GO:0000122=GO_REF:0000019, GO:0003677=PMID:10854790, GO:0006351=GO_REF:0000037, GO:0042637=GO_REF:0000019} Q9UMQ3 Homeobox protein BarH-like 2 protein 20080305 {GO:0005667=IEA, GO:0014902=IEA, GO:0000976=IEA, GO:0003700=IEA, GO:0001502=IEA, GO:0045944=IEA, GO:0003682=IEA, GO:0005634=IEA, GO:0000122=IEA, GO:0003677=IDA, GO:0006351=IEA, GO:0042637=IEA} cartilage condensation, catagen, myotube differentiation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus, transcription factor complex DNA binding, chromatin binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding Human BASP1 PINC UniProtKB {GO:0008406=GO_REF:0000024, GO:0005515=PMID:19050011, GO:0072112=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0044212=GO_REF:0000024, GO:0003714=PMID:14701728, GO:0019904=PMID:14701728, GO:0007356=GO_REF:0000024, GO:0060231=GO_REF:0000024, GO:0060421=GO_REF:0000024, GO:0005634=PMID:14701728, GO:0072075=GO_REF:0000024, GO:0030426=GO_REF:0000039, GO:0005737=PMID:14701728, GO:0008180=PMID:18850735, GO:0016607=GO_REF:0000024, GO:0060539=GO_REF:0000024, GO:2001076=GO_REF:0000024, GO:0005856=PMID:9749536, GO:0045892=PMID:19050011} P80723 Brain acid soluble protein 1 protein 20030904 {GO:0008406=ISS, GO:0005515=IPI, GO:0072112=ISS, GO:0005886=IEA, GO:0044212=ISS, GO:0003714=IMP, GO:0019904=IPI, GO:0007356=ISS, GO:0060231=ISS, GO:0060421=ISS, GO:0005634=IDA, GO:0072075=ISS, GO:0030426=IEA, GO:0005737=IDA, GO:0008180=IDA, GO:0016607=ISS, GO:0060539=ISS, GO:2001076=ISS, GO:0005856=TAS, GO:0045892=IDA} diaphragm development, glomerular visceral epithelial cell differentiation, gonad development, mesenchymal to epithelial transition, metanephric mesenchyme development, negative regulation of transcription, DNA-dependent, positive regulation of heart growth, positive regulation of metanephric ureteric bud development, thorax and anterior abdomen determination cytoplasm, cytoskeleton, growth cone, nuclear speck, nucleus, plasma membrane, signalosome protein binding, protein domain specific binding, transcription corepressor activity, transcription regulatory region DNA binding Human BATF UniProtKB UniProtKB {GO:0005515=PMID:8954125, GO:0002320=GO_REF:0000024, GO:0003700=GO_REF:0000024, GO:0030330=GO_REF:0000024, GO:0072539=GO_REF:0000024, GO:0045190=GO_REF:0000024, GO:0042832=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0001816=GO_REF:0000024, GO:0060218=GO_REF:0000024, GO:0072540=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0006974=GO_REF:0000024, GO:0043565=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0045064=GO_REF:0000024, GO:0043011=GO_REF:0000024} Q16520 Basic leucine zipper transcriptional factor ATF-like protein 20121102 {GO:0005515=IPI, GO:0002320=ISS, GO:0003700=ISS, GO:0030330=ISS, GO:0072539=ISS, GO:0045190=ISS, GO:0042832=ISS, GO:0005634=ISS, GO:0001816=ISS, GO:0060218=ISS, GO:0072540=ISS, GO:0006351=IEA, GO:0006974=ISS, GO:0043565=ISS, GO:0005737=ISS, GO:0045064=ISS, GO:0043011=ISS} DNA damage response, signal transduction by p53 class mediator, T-helper 17 cell differentiation, T-helper 17 cell lineage commitment, T-helper 2 cell differentiation, cytokine production, defense response to protozoan, hematopoietic stem cell differentiation, isotype switching, lymphoid progenitor cell differentiation, myeloid dendritic cell differentiation, response to DNA damage stimulus, transcription, DNA-dependent cytoplasm, nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:O35284 BATF2 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0042832=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0043011=GO_REF:0000024, GO:0006351=GO_REF:0000037} Q8N1L9 Basic leucine zipper transcriptional factor ATF-like 2 protein 20130415 {GO:0005515=IPI, GO:0043565=IEA, GO:0003700=IEA, GO:0042832=ISS, GO:0005634=IEA, GO:0043011=ISS, GO:0006351=IEA} defense response to protozoan, myeloid dendritic cell differentiation, transcription, DNA-dependent nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:P17275 BATF3 PINC UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0006366=PMID:10878360, GO:0003714=PMID:10878360, GO:0005634=GO_REF:0000039, GO:0043011=GO_REF:0000024, GO:0097028=GO_REF:0000024, GO:0009615=GO_REF:0000024} Q9NR55 Basic leucine zipper transcriptional factor ATF-like 3 protein 20030904 {GO:0043565=IEA, GO:0003700=IEA, GO:0006366=TAS, GO:0003714=TAS, GO:0005634=IEA, GO:0043011=ISS, GO:0097028=ISS, GO:0009615=ISS} dendritic cell differentiation, myeloid dendritic cell differentiation, response to virus, transcription from RNA polymerase II promoter nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human BAX BHF-UCL UniProtKB {GO:0043496=PMID:9111042, GO:0005515=PMID:16113678, GO:0002358=GO_REF:0000019, GO:0043497=PMID:9111042, GO:0009651=GO_REF:0000019, GO:0060041=GO_REF:0000019, GO:0051402=GO_REF:0000019, GO:0007281=GO_REF:0000019, GO:0048678=GO_REF:0000019, GO:0042803=PMID:9111042, GO:0006808=GO_REF:0000019, GO:0035234=GO_REF:0000019, GO:0042802=PMID:16113678, GO:0048597=GO_REF:0000019, GO:0005757=PMID:9843949, GO:0034644=GO_REF:0000019, GO:0043524=GO_REF:0000019, GO:0008053=PMID:14769861, GO:0008637=PMID:9843949, GO:0043525=PMID:15637643, GO:0097136=PMID:21199865, GO:0002904=GO_REF:0000019, GO:0051260=PMID:14522999, GO:0002262=GO_REF:0000019, GO:0010332=GO_REF:0000019, GO:0046982=PMID:9111042, GO:0006687=GO_REF:0000019, GO:0071310=GO_REF:0000019, GO:0001844=GO_REF:0000019, GO:0009636=PMID:16307838, GO:2001244=PMID:14963330, GO:0010248=PMID:9843949, GO:0009566=GO_REF:0000019, GO:0033599=GO_REF:0000019, GO:0046930=PMID:9219694, GO:0070059=PMID:16645094, GO:0005789=PMID:16424160, GO:0030264=PMID:11350920, GO:1990009=PMID:10702418, GO:0032471=GO_REF:0000019, GO:0032091=PMID:9388232, GO:0001783=PMID:16424160, GO:0021987=GO_REF:0000019, GO:0001782=GO_REF:0000019, GO:0005783=PMID:16424160, GO:0060068=GO_REF:0000019, GO:0006927=PMID:10739008, GO:0048147=GO_REF:0000019, GO:0048515=GO_REF:0000019, GO:0005634=PMID:15102863, GO:0005741=Reactome:REACT_1286, GO:0001836=PMID:9843949, GO:0006922=PMID:11350920, GO:0008289=PMID:14522999, GO:0005829=PMID:17823127, GO:0005739=PMID:17823127, GO:0048087=GO_REF:0000019, GO:0001541=GO_REF:0000019, GO:0048873=GO_REF:0000019, GO:0032976=PMID:9843949, GO:0033137=GO_REF:0000019, GO:0001777=GO_REF:0000019, GO:0051726=GO_REF:0000019, GO:0001101=GO_REF:0000019, GO:0042475=GO_REF:0000019, GO:0051281=GO_REF:0000019, GO:0035108=GO_REF:0000019, GO:0008635=PMID:15214043, GO:0043065=PMID:17289999, GO:0060058=GO_REF:0000019, GO:0006919=PMID:11912183, GO:0051434=PMID:17052454, GO:0001822=GO_REF:0000019, GO:1901030=Reactome:REACT_584, GO:0051881=PMID:9843949, GO:0006915=PMID:9219694, GO:0045136=GO_REF:0000019, GO:0006917=PMID:11912183, GO:0021854=GO_REF:0000019, GO:0043653=PMID:12499352, GO:0097190=PMID:16424160, GO:0097193=Reactome:REACT_964, GO:0006974=GO_REF:0000019, GO:0044445=GO_REF:0000019, GO:0006309=PMID:11350920, GO:0001974=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0046666=GO_REF:0000019, GO:0002352=GO_REF:0000019, GO:0001764=GO_REF:0000019, GO:0060011=GO_REF:0000019, GO:0015267=PMID:9219694} Q07812 Apoptosis regulator BAX protein 20080718 {GO:0043496=IDA, GO:0005515=IPI, GO:0002358=IEA, GO:0043497=IPI, GO:0009651=IEA, GO:0060041=IEA, GO:0051402=IEA, GO:0007281=IEA, GO:0048678=IEA, GO:0042803=IPI, GO:0006808=IEA, GO:0035234=IEA, GO:0042802=IPI, GO:0048597=IEA, GO:0005757=IDA, GO:0034644=IEA, GO:0043524=IEA, GO:0008053=IDA, GO:0008637=IDA, GO:0043525=IDA, GO:0097136=IDA, GO:0002904=IEA, GO:0051260=IDA, GO:0002262=IEA, GO:0010332=IEA, GO:0046982=IPI, GO:0006687=IEA, GO:0071310=IEA, GO:0001844=IEA, GO:0009636=IDA, GO:2001244=IMP, GO:0010248=IDA, GO:0009566=IEA, GO:0033599=IEA, GO:0046930=IDA, GO:0070059=IMP, GO:0005789=IDA, GO:0030264=IMP, GO:1990009=IMP, GO:0032471=IEA, GO:0032091=IDA, GO:0001783=IDA, GO:0021987=IEA, GO:0001782=IEA, GO:0005783=IDA, GO:0060068=IEA, GO:0006927=IMP, GO:0048147=IEA, GO:0048515=IEA, GO:0005634=IMP, GO:0005741=TAS, GO:0001836=IDA, GO:0006922=IMP, GO:0008289=IDA, GO:0005829=IDA, GO:0005739=IDA, GO:0048087=IEA, GO:0001541=IEA, GO:0048873=IEA, GO:0032976=IDA, GO:0033137=IEA, GO:0001777=IEA, GO:0051726=IEA, GO:0001101=IEA, GO:0042475=IEA, GO:0051281=IEA, GO:0035108=IEA, GO:0008635=IDA, GO:0043065=IMP, GO:0060058=IEA, GO:0006919=IDA, GO:0051434=IPI, GO:0001822=IEA, GO:1901030=TAS, GO:0051881=IDA, GO:0006915=IDA, GO:0045136=IEA, GO:0006917=IDA, GO:0021854=IEA, GO:0043653=IDA, GO:0097190=IDA, GO:0097193=TAS, GO:0006974=IEA, GO:0044445=IEA, GO:0006309=IMP, GO:0001974=IEA, GO:0019048=IEA, GO:0046666=IEA, GO:0002352=IEA, GO:0001764=IEA, GO:0060011=IEA, GO:0015267=IDA} B cell apoptotic process, B cell homeostasis, B cell homeostatic proliferation, B cell negative selection, Sertoli cell proliferation, T cell homeostatic proliferation, activation of cysteine-type endopeptidase activity involved in apoptotic process, activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c, apoptotic DNA fragmentation, apoptotic mitochondrial changes, apoptotic process, apoptotic signaling pathway, blood vessel remodeling, cellular response to UV, cellular response to organic substance, cerebral cortex development, cleavage of lamin involved in execution phase of apoptosis, development of secondary sexual characteristics, establishment or maintenance of transmembrane electrochemical gradient, fertilization, germ cell development, germ cell programmed cell death, glycosphingolipid metabolic process, homeostasis of number of cells within a tissue, hypothalamus development, induction of apoptosis, intrinsic apoptotic signaling pathway, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, kidney development, limb morphogenesis, mitochondrial fragmentation involved in apoptotic process, mitochondrial fusion, myeloid cell homeostasis, negative regulation of fibroblast proliferation, negative regulation of neuron apoptotic process, negative regulation of peptidyl-serine phosphorylation, negative regulation of protein binding, neuron apoptotic process, neuron migration, nuclear fragmentation involved in apoptotic nuclear change, odontogenesis of dentin-containing tooth, ovarian follicle development, positive regulation of B cell apoptotic process, positive regulation of apoptotic process, positive regulation of apoptotic process involved in mammary gland involution, positive regulation of developmental pigmentation, positive regulation of intrinsic apoptotic signaling pathway, positive regulation of mitochondrial outer membrane permeabilization, positive regulation of neuron apoptotic process, positive regulation of release of sequestered calcium ion into cytosol, post-embryonic camera-type eye morphogenesis, protein homooligomerization, protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, reduction of endoplasmic reticulum calcium ion concentration, regulation of cell cycle, regulation of mammary gland epithelial cell proliferation, regulation of mitochondrial membrane potential, regulation of nitrogen utilization, regulation of protein heterodimerization activity, regulation of protein homodimerization activity, release of cytochrome c from mitochondria, release of matrix enzymes from mitochondria, response to DNA damage stimulus, response to acid, response to axon injury, response to gamma radiation, response to salt stress, response to toxic substance, retina development in camera-type eye, retinal cell apoptotic process, retinal cell programmed cell death, spermatid differentiation, transformed cell apoptotic process, vagina development, virus-host interaction Bcl-2 family protein complex, cytosol, cytosolic part, endoplasmic reticulum, endoplasmic reticulum membrane, mitochondrial outer membrane, mitochondrial permeability transition pore complex, mitochondrion, nucleus, pore complex BH3 domain binding, channel activity, identical protein binding, lipid binding, protein binding, protein heterodimerization activity, protein homodimerization activity Human BAZ1A BHF-UCL UniProtKB {GO:0005515=PMID:17519354, GO:0006261=PMID:12434153, GO:0006355=PMID:10662543, GO:0008623=PMID:10880450, GO:0016590=PMID:10662543, GO:0006338=PMID:10662543, GO:0008270=GO_REF:0000002, GO:0000228=GO_REF:0000019, GO:0006351=PMID:10662543, GO:0004402=PMID:10662543} Q9NRL2 Bromodomain adjacent to zinc finger domain protein 1A protein 20100527 {GO:0005515=IPI, GO:0006261=IDA, GO:0006355=NAS, GO:0008623=IDA, GO:0016590=TAS, GO:0006338=TAS, GO:0008270=IEA, GO:0000228=IEA, GO:0006351=NAS, GO:0004402=TAS} DNA-dependent DNA replication, chromatin remodeling, regulation of transcription, DNA-dependent, transcription, DNA-dependent ACF complex, CHRAC, nuclear chromosome histone acetyltransferase activity, protein binding, zinc ion binding Human BAZ1B BHF-UCL UniProtKB {GO:0005515=PMID:19776015, GO:0000793=GO_REF:0000019, GO:0071778=PMID:12837248, GO:0006302=GO_REF:0000024, GO:0071884=PMID:12837248, GO:0042809=PMID:12837248, GO:0034725=PMID:12837248, GO:0070577=PMID:16252006, GO:0043596=PMID:15543136, GO:0006355=GO_REF:0000024, GO:0043044=PMID:12837248, GO:0016572=PMID:19092802, GO:0006337=PMID:12837248, GO:0005524=GO_REF:0000037, GO:0006974=PMID:19092802, GO:0006351=PMID:10662543, GO:0003007=GO_REF:0000024, GO:0032947=PMID:12837248, GO:0035173=PMID:19092802, GO:0005721=GO_REF:0000019, GO:0003682=PMID:16252006, GO:0008270=PMID:11124022, GO:0004713=PMID:19092802, GO:0004715=GO_REF:0000003, GO:0048096=GO_REF:0000024} Q9UIG0 Tyrosine-protein kinase BAZ1B protein 20100624 {GO:0005515=IPI, GO:0000793=IEA, GO:0071778=IDA, GO:0006302=ISS, GO:0071884=IMP, GO:0042809=IPI, GO:0034725=IMP, GO:0070577=IDA, GO:0043596=IDA, GO:0006355=ISS, GO:0043044=IDA, GO:0016572=IDA, GO:0006337=IDA, GO:0005524=IEA, GO:0006974=IDA, GO:0006351=NAS, GO:0003007=ISS, GO:0032947=IDA, GO:0035173=IDA, GO:0005721=IEA, GO:0003682=IDA, GO:0008270=NAS, GO:0004713=IDA, GO:0004715=IEA, GO:0048096=ISS} ATP-dependent chromatin remodeling, DNA replication-dependent nucleosome disassembly, chromatin-mediated maintenance of transcription, double-strand break repair, heart morphogenesis, histone phosphorylation, nucleosome disassembly, regulation of transcription, DNA-dependent, response to DNA damage stimulus, transcription, DNA-dependent WINAC complex, centromeric heterochromatin, condensed chromosome, nuclear replication fork ATP binding, chromatin binding, histone acetyl-lysine binding, histone kinase activity, non-membrane spanning protein tyrosine kinase activity, protein binding, protein complex scaffold, protein tyrosine kinase activity, vitamin D receptor activator activity, vitamin D receptor binding, zinc ion binding Human UniProtKB:Q9Z277 BAZ2A BHF-UCL UniProtKB {GO:0005515=PMID:17474147, GO:0016922=PMID:10662543, GO:0016575=GO_REF:0000024, GO:0070933=GO_REF:0000019, GO:0006355=PMID:10662543, GO:0034770=GO_REF:0000019, GO:0003723=GO_REF:0000024, GO:0005730=GO_REF:0000024, GO:0033553=GO_REF:0000024, GO:0070869=GO_REF:0000019, GO:0005634=GO_REF:0000002, GO:0003677=GO_REF:0000019, GO:0006351=PMID:10662543, GO:0006306=GO_REF:0000024, GO:0000183=GO_REF:0000024, GO:0006338=PMID:11532953, GO:0070577=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0005677=GO_REF:0000024, GO:0051567=GO_REF:0000019} Q9UIF9 Bromodomain adjacent to zinc finger domain protein 2A protein 20100527 {GO:0005515=IPI, GO:0016922=NAS, GO:0016575=ISS, GO:0070933=IEA, GO:0006355=NAS, GO:0034770=IEA, GO:0003723=ISS, GO:0005730=ISS, GO:0033553=ISS, GO:0070869=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=NAS, GO:0006306=ISS, GO:0000183=ISS, GO:0006338=NAS, GO:0070577=ISS, GO:0008270=IEA, GO:0005677=ISS, GO:0051567=IEA} DNA methylation, chromatin remodeling, chromatin silencing at rDNA, heterochromatin assembly involved in chromatin silencing, histone H3-K9 methylation, histone H4 deacetylation, histone H4-K20 methylation, histone deacetylation, regulation of transcription, DNA-dependent, transcription, DNA-dependent chromatin silencing complex, nucleolus, nucleus, rDNA heterochromatin DNA binding, RNA binding, histone acetyl-lysine binding, ligand-dependent nuclear receptor binding, protein binding, zinc ion binding Human BAZ2B BHF-UCL UniProtKB {GO:0005515=PMID:10662543, GO:0006355=PMID:10662543, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=PMID:10662543} Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B protein 20100527 {GO:0005515=IPI, GO:0006355=NAS, GO:0008270=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=NAS} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, protein binding, zinc ion binding Human BBC3 BHF-UCL UniProtKB {GO:0005515=PMID:22516262, GO:0032464=PMID:21041309, GO:0034976=PMID:22761832, GO:2001056=GO_REF:0000024, GO:0051209=PMID:17024184, GO:0006919=PMID:17024184, GO:0070245=GO_REF:0000024, GO:0006915=Reactome:REACT_578, GO:0071456=PMID:20810912, GO:0005741=Reactome:REACT_21389, GO:0001836=PMID:11463392, GO:2001244=Reactome:REACT_330, GO:0006917=PMID:16608847, GO:0008340=GO_REF:0000024, GO:0097193=Reactome:REACT_964, GO:0005829=Reactome:REACT_1555, GO:0005739=PMID:11463392, GO:0042771=GO_REF:0000024, GO:0043525=GO_REF:0000024, GO:1900740=Reactome:REACT_697, GO:0070059=GO_REF:0000024, GO:0090200=PMID:21041309, GO:0032471=PMID:17024184, GO:0045926=PMID:11463392} Q9BXH1 Bcl-2-binding component 3 protein 20110317 {GO:0005515=IPI, GO:0032464=IDA, GO:0034976=IDA, GO:2001056=ISS, GO:0051209=IDA, GO:0006919=IDA, GO:0070245=ISS, GO:0006915=TAS, GO:0071456=IEP, GO:0005741=TAS, GO:0001836=IDA, GO:2001244=TAS, GO:0006917=IDA, GO:0008340=ISS, GO:0097193=TAS, GO:0005829=TAS, GO:0005739=IDA, GO:0042771=ISS, GO:0043525=ISS, GO:1900740=TAS, GO:0070059=ISS, GO:0090200=IGI, GO:0032471=IDA, GO:0045926=IMP} activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, cellular response to hypoxia, determination of adult lifespan, induction of apoptosis, intrinsic apoptotic signaling pathway, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, negative regulation of growth, positive regulation of cysteine-type endopeptidase activity, positive regulation of intrinsic apoptotic signaling pathway, positive regulation of neuron apoptotic process, positive regulation of protein homooligomerization, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, positive regulation of release of cytochrome c from mitochondria, positive regulation of thymocyte apoptotic process, reduction of endoplasmic reticulum calcium ion concentration, release of cytochrome c from mitochondria, release of sequestered calcium ion into cytosol, response to endoplasmic reticulum stress cytosol, mitochondrial outer membrane, mitochondrion protein binding Human BBOX1 HPA UniProtKB {GO:0005739=GO_REF:0000019, GO:0034641=Reactome:REACT_13, GO:0008336=Reactome:REACT_417, GO:0005506=GO_REF:0000002, GO:0045329=Reactome:REACT_2125, GO:0008270=PMID:20599753, GO:0044281=Reactome:REACT_111217, GO:0015629=GO_REF:0000052, GO:0016702=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0005829=Reactome:REACT_417} O75936 Gamma-butyrobetaine dioxygenase protein 20101115 {GO:0005739=IEA, GO:0034641=TAS, GO:0008336=TAS, GO:0005506=IEA, GO:0045329=TAS, GO:0008270=IDA, GO:0044281=TAS, GO:0015629=IDA, GO:0016702=IEA, GO:0043231=IDA, GO:0005829=TAS} carnitine biosynthetic process, cellular nitrogen compound metabolic process, small molecule metabolic process actin cytoskeleton, cytosol, intracellular membrane-bounded organelle, mitochondrion gamma-butyrobetaine dioxygenase activity, iron ion binding, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, zinc ion binding Human BBS1 BHF-UCL UniProtKB {GO:0005515=PMID:17574030, GO:0042384=PMID:17574030, GO:0034464=PMID:17574030, GO:0060170=GO_REF:0000039, GO:0005737=GO_REF:0000039, GO:0001895=PMID:17980398, GO:0043001=PMID:19150989, GO:0045494=PMID:17980398, GO:0035058=PMID:17980398, GO:0050896=GO_REF:0000037} Q8NFJ9 Bardet-Biedl syndrome 1 protein protein 20080521 {GO:0005515=IPI, GO:0042384=IMP, GO:0034464=IDA, GO:0060170=IEA, GO:0005737=IEA, GO:0001895=IMP, GO:0043001=IMP, GO:0045494=IMP, GO:0035058=IMP, GO:0050896=IEA} Golgi to plasma membrane protein transport, cilium assembly, nonmotile primary cilium assembly, photoreceptor cell maintenance, response to stimulus, retina homeostasis BBSome, cilium membrane, cytoplasm protein binding Human BBS10 BHF-UCL UniProtKB {GO:0005515=PMID:20080638, GO:0005929=GO_REF:0000039, GO:0001895=PMID:17980398, GO:0043254=PMID:22500027, GO:0045494=PMID:17980398, GO:0035058=PMID:17980398, GO:0051131=PMID:20080638, GO:0005524=GO_REF:0000037, GO:0044267=GO_REF:0000002, GO:0050896=GO_REF:0000037} Q8TAM1 Bardet-Biedl syndrome 10 protein protein 20080514 {GO:0005515=IPI, GO:0005929=IEA, GO:0001895=IMP, GO:0043254=IMP, GO:0045494=IMP, GO:0035058=IMP, GO:0051131=IMP, GO:0005524=IEA, GO:0044267=IEA, GO:0050896=IEA} cellular protein metabolic process, chaperone-mediated protein complex assembly, nonmotile primary cilium assembly, photoreceptor cell maintenance, regulation of protein complex assembly, response to stimulus, retina homeostasis cilium ATP binding, protein binding Human BBS2 BHF-UCL UniProtKB {GO:0005515=PMID:18000879, GO:0038108=GO_REF:0000024, GO:0060170=GO_REF:0000039, GO:0034464=PMID:17574030, GO:0021987=GO_REF:0000024, GO:0033365=GO_REF:0000024, GO:0043001=PMID:19150989, GO:0031514=PMID:18299575, GO:0007288=GO_REF:0000024, GO:0045494=GO_REF:0000024, GO:0032402=GO_REF:0000024, GO:0048854=GO_REF:0000024, GO:0060296=GO_REF:0000024, GO:0021756=GO_REF:0000024, GO:0021766=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0008104=GO_REF:0000024, GO:0040015=GO_REF:0000024, GO:0060271=GO_REF:0000024, GO:0010629=GO_REF:0000019, GO:0045444=GO_REF:0000024, GO:0030534=GO_REF:0000024, GO:0005932=PMID:18299575, GO:0040018=GO_REF:0000019} Q9BXC9 Bardet-Biedl syndrome 2 protein protein 20080903 {GO:0005515=IPI, GO:0038108=ISS, GO:0060170=IEA, GO:0034464=IDA, GO:0021987=ISS, GO:0033365=ISS, GO:0043001=IMP, GO:0031514=IDA, GO:0007288=ISS, GO:0045494=ISS, GO:0032402=ISS, GO:0048854=ISS, GO:0060296=ISS, GO:0021756=ISS, GO:0021766=ISS, GO:0005737=IEA, GO:0008104=ISS, GO:0040015=ISS, GO:0060271=ISS, GO:0010629=IEA, GO:0045444=ISS, GO:0030534=ISS, GO:0005932=IDA, GO:0040018=IEA} Golgi to plasma membrane protein transport, adult behavior, brain morphogenesis, cerebral cortex development, cilium morphogenesis, fat cell differentiation, hippocampus development, melanosome transport, negative regulation of appetite by leptin-mediated signaling pathway, negative regulation of gene expression, negative regulation of multicellular organism growth, photoreceptor cell maintenance, positive regulation of multicellular organism growth, protein localization, protein localization to organelle, regulation of cilium beat frequency involved in ciliary motility, sperm axoneme assembly, striatum development BBSome, cilium membrane, cytoplasm, microtubule basal body, motile cilium protein binding Human UniProtKB:Q98SP7 BBS4 HPA UniProtKB {GO:0005515=PMID:17574030, GO:0007608=GO_REF:0000024, GO:0034452=PMID:15107855, GO:0034451=PMID:15107855, GO:0007286=GO_REF:0000024, GO:0045494=GO_REF:0000024, GO:0032402=GO_REF:0000024, GO:0051877=GO_REF:0000024, GO:0001947=GO_REF:0000024, GO:0001895=GO_REF:0000024, GO:0045444=GO_REF:0000024, GO:0030534=GO_REF:0000024, GO:0005932=PMID:15107855, GO:0003085=GO_REF:0000019, GO:0000242=PMID:15107855, GO:0005813=PMID:14520415, GO:0032465=PMID:15107855, GO:0005814=PMID:15107855, GO:0046548=GO_REF:0000024, GO:0048487=PMID:17574030, GO:0001843=GO_REF:0000024, GO:0016358=GO_REF:0000024, GO:0019216=GO_REF:0000024, GO:0051457=PMID:15107855, GO:0060271=GO_REF:0000024, GO:0038108=GO_REF:0000024, GO:0060170=PMID:17574030, GO:0021987=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0060027=GO_REF:0000024, GO:0040018=GO_REF:0000019, GO:0034464=PMID:17574030, GO:0033365=GO_REF:0000024, GO:0043014=PMID:17574030, GO:0031514=PMID:18299575, GO:0045724=GO_REF:0000024, GO:0000226=GO_REF:0000024, GO:0031513=PMID:17574030, GO:0046907=GO_REF:0000024, GO:0035058=GO_REF:0000024, GO:0003777=PMID:15107855, GO:0048854=GO_REF:0000024, GO:0060296=GO_REF:0000024, GO:0051297=PMID:15107855, GO:0021756=GO_REF:0000024, GO:0021766=GO_REF:0000024, GO:0042384=GO_REF:0000024, GO:0050893=PMID:14520415, GO:0010629=GO_REF:0000019, GO:0034454=PMID:15107855} Q96RK4 Bardet-Biedl syndrome 4 protein protein 20111111 {GO:0005515=IPI, GO:0007608=ISS, GO:0034452=IDA, GO:0034451=IDA, GO:0007286=ISS, GO:0045494=ISS, GO:0032402=ISS, GO:0051877=ISS, GO:0001947=ISS, GO:0001895=ISS, GO:0045444=ISS, GO:0030534=ISS, GO:0005932=IDA, GO:0003085=IEA, GO:0000242=IDA, GO:0005813=IDA, GO:0032465=IMP, GO:0005814=IDA, GO:0046548=ISS, GO:0048487=IDA, GO:0001843=ISS, GO:0016358=ISS, GO:0019216=ISS, GO:0051457=IGI, GO:0060271=ISS, GO:0038108=ISS, GO:0060170=IDA, GO:0021987=ISS, GO:0005737=IDA, GO:0060027=ISS, GO:0040018=IEA, GO:0034464=IDA, GO:0033365=ISS, GO:0043014=IDA, GO:0031514=IDA, GO:0045724=ISS, GO:0000226=ISS, GO:0031513=IDA, GO:0046907=ISS, GO:0035058=ISS, GO:0003777=IMP, GO:0048854=ISS, GO:0060296=ISS, GO:0051297=IMP, GO:0021756=ISS, GO:0021766=ISS, GO:0042384=ISS, GO:0050893=TAS, GO:0010629=IEA, GO:0034454=IMP} adult behavior, brain morphogenesis, centrosome organization, cerebral cortex development, cilium assembly, cilium morphogenesis, convergent extension involved in gastrulation, dendrite development, fat cell differentiation, heart looping, hippocampus development, intracellular transport, maintenance of protein location in nucleus, melanosome transport, microtubule anchoring at centrosome, microtubule cytoskeleton organization, negative regulation of appetite by leptin-mediated signaling pathway, negative regulation of gene expression, negative regulation of systemic arterial blood pressure, neural tube closure, nonmotile primary cilium assembly, photoreceptor cell maintenance, pigment granule aggregation in cell center, positive regulation of cilium assembly, positive regulation of multicellular organism growth, protein localization to organelle, regulation of cilium beat frequency involved in ciliary motility, regulation of cytokinesis, regulation of lipid metabolic process, retina homeostasis, retinal rod cell development, sensory perception of smell, sensory processing, spermatid development, striatum development BBSome, centriolar satellite, centriole, centrosome, cilium membrane, cytoplasm, microtubule basal body, motile cilium, nonmotile primary cilium, pericentriolar material alpha-tubulin binding, beta-tubulin binding, dynactin binding, microtubule motor activity, protein binding Human BBS5 BHF-UCL UniProtKB {GO:0005515=PMID:20080638, GO:0060170=GO_REF:0000039, GO:0034464=PMID:17574030, GO:0032266=PMID:17574030, GO:0032402=GO_REF:0000024, GO:0005622=GO_REF:0000054, GO:0001947=GO_REF:0000024, GO:0042384=PMID:17574030, GO:0005737=GO_REF:0000039, GO:0009296=GO_REF:0000024, GO:0005932=GO_REF:0000024, GO:0007601=GO_REF:0000037, GO:0050896=GO_REF:0000037} Q8N3I7 Bardet-Biedl syndrome 5 protein protein 20080812 {GO:0005515=IPI, GO:0060170=IEA, GO:0034464=IDA, GO:0032266=IDA, GO:0032402=ISS, GO:0005622=IDA, GO:0001947=ISS, GO:0042384=IMP, GO:0005737=IEA, GO:0009296=ISS, GO:0005932=ISS, GO:0007601=IEA, GO:0050896=IEA} cilium assembly, flagellum assembly, heart looping, melanosome transport, response to stimulus, visual perception BBSome, cilium membrane, cytoplasm, intracellular, microtubule basal body phosphatidylinositol-3-phosphate binding, protein binding Human UniProtKB:Q7ZWB7 BBS7 BHF-UCL UniProtKB {GO:0005515=PMID:18000879, GO:0034464=PMID:17574030, GO:0060170=GO_REF:0000039, GO:0005813=PMID:21399614, GO:0007368=GO_REF:0000024, GO:0048546=GO_REF:0000024, GO:0051877=GO_REF:0000024, GO:0032402=GO_REF:0000024, GO:0001947=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0060271=GO_REF:0000024, GO:0045444=GO_REF:0000024, GO:0007601=GO_REF:0000037, GO:0050896=GO_REF:0000037} Q8IWZ6 Bardet-Biedl syndrome 7 protein protein 20080812 {GO:0005515=IPI, GO:0034464=IDA, GO:0060170=IEA, GO:0005813=IDA, GO:0007368=ISS, GO:0048546=ISS, GO:0051877=ISS, GO:0032402=ISS, GO:0001947=ISS, GO:0005737=IEA, GO:0060271=ISS, GO:0045444=ISS, GO:0007601=IEA, GO:0050896=IEA} cilium morphogenesis, determination of left/right symmetry, digestive tract morphogenesis, fat cell differentiation, heart looping, melanosome transport, pigment granule aggregation in cell center, response to stimulus, visual perception BBSome, centrosome, cilium membrane, cytoplasm protein binding Human UniProtKB:Q08C18 BBS9 HPA UniProtKB {GO:0005515=PMID:22500027, GO:0003674=GO_REF:0000015, GO:0060170=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0034464=PMID:17574030, GO:0005815=GO_REF:0000039, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0045444=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0007601=GO_REF:0000037, GO:0050896=GO_REF:0000037} Q3SYG4 Protein PTHB1 protein 20101115 {GO:0005515=IPI, GO:0003674=ND, GO:0060170=IEA, GO:0005737=IDA, GO:0034464=IDA, GO:0005815=IEA, GO:0005886=IDA, GO:0005730=IDA, GO:0045444=ISS, GO:0005634=IDA, GO:0007601=IEA, GO:0050896=IEA} fat cell differentiation, response to stimulus, visual perception BBSome, cilium membrane, cytoplasm, microtubule organizing center, nucleolus, nucleus, plasma membrane molecular_function, protein binding Human BBX UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8WY36 HMG box transcription factor BBX protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding Human UniProtKB-SubCell:SL-0191 BCAM BHF-UCL UniProtKB {GO:0007165=PMID:7777537, GO:0007160=PMID:16236823, GO:0005886=PMID:9166867, GO:0009986=PMID:12493773, GO:0016020=GO_REF:0000038, GO:0005887=PMID:7777537, GO:0043236=PMID:16236823, GO:0005055=PMID:16236823, GO:0007155=PMID:7954395, GO:0009897=PMID:16236823, GO:0004888=PMID:7777537} P50895 Basal cell adhesion molecule protein 20090408 {GO:0007165=TAS, GO:0007160=IMP, GO:0005886=TAS, GO:0009986=IDA, GO:0016020=IEA, GO:0005887=TAS, GO:0043236=IMP, GO:0005055=IMP, GO:0007155=TAS, GO:0009897=IC, GO:0004888=TAS} cell adhesion, cell-matrix adhesion, signal transduction cell surface, external side of plasma membrane, integral to plasma membrane, membrane, plasma membrane laminin binding, laminin receptor activity, transmembrane signaling receptor activity Human BCAN Reactome UniProtKB {GO:0005796=Reactome:REACT_121341, GO:0005975=Reactome:REACT_474, GO:0005578=GO_REF:0000039, GO:0005576=Reactome:REACT_121341, GO:0044281=Reactome:REACT_111217, GO:0031225=GO_REF:0000037, GO:0030208=Reactome:REACT_120800, GO:0021766=GO_REF:0000019, GO:0030207=Reactome:REACT_120888, GO:0030206=Reactome:REACT_120989, GO:0005540=GO_REF:0000037, GO:0030246=GO_REF:0000002, GO:0007155=GO_REF:0000002, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408, GO:0043202=Reactome:REACT_121272} Q96GW7 Brevican core protein protein 20130301 {GO:0005796=TAS, GO:0005975=TAS, GO:0005578=IEA, GO:0005576=TAS, GO:0044281=TAS, GO:0031225=IEA, GO:0030208=TAS, GO:0021766=IEA, GO:0030207=TAS, GO:0030206=TAS, GO:0005540=IEA, GO:0030246=IEA, GO:0007155=IEA, GO:0030204=TAS, GO:0030203=TAS, GO:0043202=TAS} carbohydrate metabolic process, cell adhesion, chondroitin sulfate biosynthetic process, chondroitin sulfate catabolic process, chondroitin sulfate metabolic process, dermatan sulfate biosynthetic process, glycosaminoglycan metabolic process, hippocampus development, small molecule metabolic process Golgi lumen, anchored to membrane, extracellular region, lysosomal lumen, proteinaceous extracellular matrix carbohydrate binding, hyaluronic acid binding Human BCAP29 UniProtKB UniProtKB {GO:0005783=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0016192=GO_REF:0000037, GO:0006886=GO_REF:0000002} Q9UHQ4 B-cell receptor-associated protein 29 protein 20130413 {GO:0005783=IEA, GO:0005789=IEA, GO:0006915=IEA, GO:0016021=IEA, GO:0016192=IEA, GO:0006886=IEA} apoptotic process, intracellular protein transport, vesicle-mediated transport endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane Human UniProtKB-SubCell:SL-0097 BCAP31 HPA UniProtKB {GO:0005515=PMID:21183955, GO:0002474=Reactome:REACT_75820, GO:0035584=PMID:21183955, GO:0005886=GO_REF:0000019, GO:0005783=GO_REF:0000052, GO:0005102=GO_REF:0000029, GO:0006915=Reactome:REACT_578, GO:0007283=GO_REF:0000019, GO:0006886=GO_REF:0000002, GO:0007204=PMID:21183955, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_13554, GO:0043280=PMID:21183955, GO:0006955=GO_REF:0000029, GO:0000139=GO_REF:0000019, GO:0051561=PMID:21183955, GO:0005887=PMID:8706661, GO:0033116=GO_REF:0000039, GO:0005789=Reactome:REACT_13554, GO:0071556=Reactome:REACT_75922, GO:0016021=GO_REF:0000002, GO:0016192=GO_REF:0000037, GO:0032471=PMID:21183955} P51572 B-cell receptor-associated protein 31 protein 20080205 {GO:0005515=IPI, GO:0002474=TAS, GO:0035584=IMP, GO:0005886=IEA, GO:0005783=IDA, GO:0005102=NAS, GO:0006915=TAS, GO:0007283=IEA, GO:0006886=IEA, GO:0007204=IMP, GO:0006921=TAS, GO:0005829=TAS, GO:0043280=IMP, GO:0006955=NAS, GO:0000139=IEA, GO:0051561=IMP, GO:0005887=IDA, GO:0033116=IEA, GO:0005789=TAS, GO:0071556=TAS, GO:0016021=IEA, GO:0016192=IEA, GO:0032471=IMP} antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, calcium-mediated signaling using intracellular calcium source, cellular component disassembly involved in execution phase of apoptosis, elevation of cytosolic calcium ion concentration, elevation of mitochondrial calcium ion concentration, immune response, intracellular protein transport, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, reduction of endoplasmic reticulum calcium ion concentration, spermatogenesis, vesicle-mediated transport Golgi membrane, cytosol, endoplasmic reticulum, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment membrane, integral to lumenal side of endoplasmic reticulum membrane, integral to membrane, integral to plasma membrane, plasma membrane protein binding, receptor binding Human BCAR1 BHF-UCL UniProtKB {GO:0008286=GO_REF:0000024, GO:0005515=PMID:19732724, GO:0050853=PMID:9020138, GO:0050852=PMID:9295052, GO:0017124=GO_REF:0000037, GO:0005886=PMID:21245381, GO:0008283=PMID:10639512, GO:0001558=PMID:11607844, GO:0050851=PMID:10587647, GO:0005829=Reactome:REACT_16951, GO:0005737=PMID:8070403, GO:0007173=GO_REF:0000024, GO:0035729=PMID:21245381, GO:0007015=PMID:16105984, GO:0004871=PMID:8070403, GO:0007155=GO_REF:0000037, GO:0048010=PMID:21245381, GO:0048011=GO_REF:0000024, GO:0048012=PMID:21245381, GO:0030335=PMID:9472046, GO:0019901=PMID:9020138, GO:0030168=Reactome:REACT_798, GO:0042981=PMID:11607844, GO:0001726=PMID:9472046, GO:0030027=GO_REF:0000019, GO:0010595=PMID:21245381, GO:0007186=PMID:10092204, GO:0016477=PMID:9425168, GO:0060326=PMID:21245381, GO:0007596=Reactome:REACT_604, GO:0007229=PMID:8649368, GO:0048008=GO_REF:0000024, GO:0005925=PMID:21245381, GO:0051301=PMID:10675905} P56945 Breast cancer anti-estrogen resistance protein 1 protein 20121127 {GO:0008286=ISS, GO:0005515=IPI, GO:0050853=IDA, GO:0050852=NAS, GO:0017124=IEA, GO:0005886=IDA, GO:0008283=TAS, GO:0001558=TAS, GO:0050851=IDA, GO:0005829=TAS, GO:0005737=IDA, GO:0007173=ISS, GO:0035729=IMP, GO:0007015=IDA, GO:0004871=TAS, GO:0007155=IEA, GO:0048010=IMP, GO:0048011=ISS, GO:0048012=IMP, GO:0030335=IDA, GO:0019901=IPI, GO:0030168=TAS, GO:0042981=TAS, GO:0001726=IDA, GO:0030027=IEA, GO:0010595=IDA, GO:0007186=NAS, GO:0016477=IDA, GO:0060326=IMP, GO:0007596=TAS, GO:0007229=IDA, GO:0048008=ISS, GO:0005925=IDA, GO:0051301=NAS} B cell receptor signaling pathway, G-protein coupled receptor signaling pathway, T cell receptor signaling pathway, actin filament organization, antigen receptor-mediated signaling pathway, blood coagulation, cell adhesion, cell chemotaxis, cell division, cell migration, cell proliferation, cellular response to hepatocyte growth factor stimulus, epidermal growth factor receptor signaling pathway, hepatocyte growth factor receptor signaling pathway, insulin receptor signaling pathway, integrin-mediated signaling pathway, neurotrophin TRK receptor signaling pathway, platelet activation, platelet-derived growth factor receptor signaling pathway, positive regulation of cell migration, positive regulation of endothelial cell migration, regulation of apoptotic process, regulation of cell growth, vascular endothelial growth factor receptor signaling pathway cytoplasm, cytosol, focal adhesion, lamellipodium, plasma membrane, ruffle SH3 domain binding, protein binding, protein kinase binding, signal transducer activity Human BCAR3 InterPro UniProtKB {GO:0005085=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0007165=PMID:9582273, GO:0007264=GO_REF:0000002, GO:0042493=PMID:9582273} Q5TEW3 Breast cancer anti-estrogen resistance protein 3 protein 20130413 {GO:0005085=IEA, GO:0005622=IEA, GO:0007165=TAS, GO:0007264=IEA, GO:0042493=TAS} response to drug, signal transduction, small GTPase mediated signal transduction intracellular guanyl-nucleotide exchange factor activity Human InterPro:IPR001895 BCAS1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} O75363 Breast carcinoma-amplified sequence 1 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 BCAS2 MGI UniProtKB {GO:0005515=PMID:20176811, GO:0008380=PMID:9731529, GO:0006397=GO_REF:0000037, GO:0000375=PMID:9731529, GO:0005730=GO_REF:0000039, GO:0005681=PMID:12169396} O75934 Pre-mRNA-splicing factor SPF27 protein 20060110 {GO:0005515=IPI, GO:0008380=TAS, GO:0006397=IEA, GO:0000375=TAS, GO:0005730=IEA, GO:0005681=IDA} RNA splicing, RNA splicing, via transesterification reactions, mRNA processing nucleolus, spliceosomal complex protein binding Human BCAS3 IntAct UniProtKB {GO:0005515=PMID:22300583, GO:0005737=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0071944=GO_REF:0000019} Q9H6U6 Breast carcinoma-amplified sequence 3 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0005634=IEA, GO:0071944=IEA} cell periphery, cytoplasm, nucleus protein binding Human UniProtKB:P08670 BCAS4 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q8TDM0 Breast carcinoma-amplified sequence 4 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 BCAT1 Reactome UniProtKB {GO:0034641=Reactome:REACT_13, GO:0000082=PMID:8692959, GO:0009082=GO_REF:0000037, GO:0008283=PMID:6933702, GO:0004084=Reactome:REACT_21283, GO:0052656=GO_REF:0000003, GO:0052654=GO_REF:0000003, GO:0052655=GO_REF:0000003, GO:0009083=Reactome:REACT_197, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0005829=Reactome:REACT_21283} P54687 Branched-chain-amino-acid aminotransferase, cytosolic protein 20130213 {GO:0034641=TAS, GO:0000082=TAS, GO:0009082=IEA, GO:0008283=TAS, GO:0004084=EXP, GO:0052656=IEA, GO:0052654=IEA, GO:0052655=IEA, GO:0009083=TAS, GO:0044281=TAS, GO:0003824=IEA, GO:0005829=TAS} G1/S transition of mitotic cell cycle, branched-chain amino acid biosynthetic process, branched-chain amino acid catabolic process, cell proliferation, cellular nitrogen compound metabolic process, small molecule metabolic process cytosol L-isoleucine transaminase activity, L-leucine transaminase activity, L-valine transaminase activity, branched-chain-amino-acid transaminase activity, catalytic activity Human BCAT2 Reactome UniProtKB {GO:0052656=GO_REF:0000003, GO:0004084=Reactome:REACT_21409, GO:0052654=GO_REF:0000003, GO:0052655=GO_REF:0000003, GO:0009083=Reactome:REACT_197, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0010817=GO_REF:0000019, GO:0005739=PMID:9165094, GO:0034641=Reactome:REACT_13, GO:0009082=GO_REF:0000037, GO:0009081=GO_REF:0000002, GO:0005759=Reactome:REACT_21409, GO:0006573=GO_REF:0000019, GO:0006551=GO_REF:0000019, GO:0006550=GO_REF:0000019} O15382 Branched-chain-amino-acid aminotransferase, mitochondrial protein 20130213 {GO:0052656=IEA, GO:0004084=EXP, GO:0052654=IEA, GO:0052655=IEA, GO:0009083=TAS, GO:0044281=TAS, GO:0003824=IEA, GO:0010817=IEA, GO:0005739=TAS, GO:0034641=TAS, GO:0009082=IEA, GO:0009081=IEA, GO:0005759=TAS, GO:0006573=IEA, GO:0006551=IEA, GO:0006550=IEA} branched-chain amino acid biosynthetic process, branched-chain amino acid catabolic process, branched-chain amino acid metabolic process, cellular nitrogen compound metabolic process, isoleucine catabolic process, leucine metabolic process, regulation of hormone levels, small molecule metabolic process, valine metabolic process mitochondrial matrix, mitochondrion L-isoleucine transaminase activity, L-leucine transaminase activity, L-valine transaminase activity, branched-chain-amino-acid transaminase activity, catalytic activity Human BCCIP MGI UniProtKB {GO:0005515=PMID:18440304, GO:0007049=GO_REF:0000037, GO:0019908=PMID:10878006, GO:0006281=GO_REF:0000037, GO:0005634=PMID:10878006, GO:0061101=PMID:18440304, GO:0000079=PMID:10878006, GO:0019207=PMID:10878006} Q9P287 BRCA2 and CDKN1A-interacting protein protein 20091019 {GO:0005515=IPI, GO:0007049=IEA, GO:0019908=IDA, GO:0006281=IEA, GO:0005634=TAS, GO:0061101=IDA, GO:0000079=IDA, GO:0019207=IDA} DNA repair, cell cycle, neuroendocrine cell differentiation, regulation of cyclin-dependent protein serine/threonine kinase activity nuclear cyclin-dependent protein kinase holoenzyme complex, nucleus kinase regulator activity, protein binding Human BCDIN3D UniProtKB UniProtKB {GO:0001510=PMID:23063121, GO:0005737=PMID:23063121, GO:2000632=PMID:23063121, GO:0008171=PMID:23063121, GO:0008173=PMID:23063121, GO:0010586=PMID:23063121} Q7Z5W3 Pre-miRNA 5'-monophosphate methyltransferase protein 20121022 {GO:0001510=IDA, GO:0005737=IDA, GO:2000632=IDA, GO:0008171=IDA, GO:0008173=IDA, GO:0010586=IDA} RNA methylation, miRNA metabolic process, negative regulation of pre-miRNA processing cytoplasm O-methyltransferase activity, RNA methyltransferase activity Human BCHE ENSEMBL UniProtKB {GO:0004091=GO_REF:0000002, GO:0003990=GO_REF:0000024, GO:0005783=GO_REF:0000019, GO:0004104=PMID:19452557, GO:0005576=Reactome:REACT_19294, GO:0003824=PMID:11569538, GO:0005615=GO_REF:0000033, GO:0019695=GO_REF:0000033, GO:0007271=GO_REF:0000033, GO:0001540=PMID:11569538, GO:0016020=GO_REF:0000002, GO:0005641=GO_REF:0000019, GO:0050783=PMID:8622553, GO:0005788=GO_REF:0000033, GO:0019899=PMID:11569538, GO:0044267=Reactome:REACT_17015} Q96HL2 Cholinesterase protein 20130413 {GO:0004091=IEA, GO:0003990=ISS, GO:0005783=IEA, GO:0004104=IDA, GO:0005576=TAS, GO:0003824=NAS, GO:0005615=IBA, GO:0019695=IBA, GO:0007271=IBA, GO:0001540=NAS, GO:0016020=IEA, GO:0005641=IEA, GO:0050783=TAS, GO:0005788=IBA, GO:0019899=NAS, GO:0044267=TAS} cellular protein metabolic process, choline metabolic process, cocaine metabolic process, synaptic transmission, cholinergic endoplasmic reticulum, endoplasmic reticulum lumen, extracellular region, extracellular space, membrane, nuclear envelope lumen acetylcholinesterase activity, beta-amyloid binding, carboxylesterase activity, catalytic activity, cholinesterase activity, enzyme binding Human Ensembl:ENSMUSP00000029367 BCKDHA IntAct UniProtKB {GO:0005515=PMID:15576032, GO:0005739=PMID:11839747, GO:0003863=GO_REF:0000003, GO:0034641=Reactome:REACT_13, GO:0005759=Reactome:REACT_1813, GO:0016831=PMID:11839747, GO:0016624=GO_REF:0000002, GO:0005947=PMID:7883996, GO:0009083=Reactome:REACT_197, GO:0044281=Reactome:REACT_111217, GO:0003826=PMID:7883996, GO:0046872=GO_REF:0000037} P12694 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial protein 20130415 {GO:0005515=IPI, GO:0005739=TAS, GO:0003863=IEA, GO:0034641=TAS, GO:0005759=TAS, GO:0016831=TAS, GO:0016624=IEA, GO:0005947=IDA, GO:0009083=TAS, GO:0044281=TAS, GO:0003826=IDA, GO:0046872=IEA} branched-chain amino acid catabolic process, cellular nitrogen compound metabolic process, small molecule metabolic process mitochondrial alpha-ketoglutarate dehydrogenase complex, mitochondrial matrix, mitochondrion 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity, alpha-ketoacid dehydrogenase activity, carboxy-lyase activity, metal ion binding, oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor, protein binding Human UniProtKB:P21953 BCKDHB IntAct UniProtKB {GO:0005515=PMID:15576032, GO:0003863=GO_REF:0000003, GO:0007584=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0009083=Reactome:REACT_197, GO:0044281=Reactome:REACT_111217, GO:0032403=GO_REF:0000019, GO:0051591=GO_REF:0000019, GO:0003826=GO_REF:0000019, GO:0005739=PMID:2022752, GO:0034641=Reactome:REACT_13, GO:0005759=Reactome:REACT_1813, GO:0016831=PMID:11839747, GO:0005947=PMID:2022752} P21953 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial protein 20130415 {GO:0005515=IPI, GO:0003863=IEA, GO:0007584=IEA, GO:0051384=IEA, GO:0009083=TAS, GO:0044281=TAS, GO:0032403=IEA, GO:0051591=IEA, GO:0003826=IEA, GO:0005739=IMP, GO:0034641=TAS, GO:0005759=TAS, GO:0016831=TAS, GO:0005947=IMP} branched-chain amino acid catabolic process, cellular nitrogen compound metabolic process, response to cAMP, response to glucocorticoid stimulus, response to nutrient, small molecule metabolic process mitochondrial alpha-ketoglutarate dehydrogenase complex, mitochondrial matrix, mitochondrion 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity, alpha-ketoacid dehydrogenase activity, carboxy-lyase activity, protein binding, protein complex binding Human UniProtKB:P12694 BCKDK UniProtKB UniProtKB {GO:0005515=PMID:21988832, GO:0005739=PMID:11839747, GO:0016310=GO_REF:0000024, GO:0016301=GO_REF:0000038, GO:0004674=GO_REF:0000024, GO:0047323=GO_REF:0000003, GO:0005947=GO_REF:0000024, GO:0009083=GO_REF:0000024, GO:0009063=PMID:2403034, GO:0005524=GO_REF:0000002} Q96G95 BCKDK protein protein 20130413 {GO:0005515=IPI, GO:0005739=TAS, GO:0016310=ISS, GO:0016301=IEA, GO:0004674=ISS, GO:0047323=IEA, GO:0005947=ISS, GO:0009083=ISS, GO:0009063=NAS, GO:0005524=IEA} branched-chain amino acid catabolic process, cellular amino acid catabolic process, phosphorylation mitochondrial alpha-ketoglutarate dehydrogenase complex, mitochondrion "ATP binding, 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)"" kinase activity, kinase activity, protein binding, protein serine/threonine kinase activity""" Human UniProtKB-KW:KW-0418 BCL10 BHF-UCL UniProtKB {GO:0005515=PMID:16280327, GO:0008219=PMID:10400625, GO:0043130=PMID:15082780, GO:0016064=GO_REF:0000019, GO:0042226=PMID:16647297, GO:0002020=PMID:18223652, GO:0043621=PMID:15125833, GO:0005764=PMID:15082780, GO:0042221=PMID:17095757, GO:0051259=PMID:14695475, GO:0002906=PMID:15878976, GO:0031398=PMID:14695475, GO:0051260=PMID:16831874, GO:0043123=PMID:12761501, GO:0031625=PMID:16395405, GO:0046696=PMID:16831874, GO:0032765=PMID:16647297, GO:0019901=PMID:17052756, GO:0003713=PMID:15207693, GO:0045416=PMID:17095757, GO:0001843=PMID:11163238, GO:0002224=PMID:16831874, GO:0043234=PMID:14695475, GO:0019209=PMID:15125833, GO:0045087=PMID:16831874, GO:0050870=GO_REF:0000019, GO:0045121=GO_REF:0000039, GO:0045893=PMID:15207693, GO:0019899=PMID:14695475, GO:0008134=PMID:15207693, GO:0005881=PMID:23264731, GO:0050852=Reactome:REACT_12526, GO:0048471=PMID:16127295, GO:0005886=Reactome:REACT_118777, GO:0050856=GO_REF:0000019, GO:0002237=PMID:16831874, GO:0009620=GO_REF:0000019, GO:0005634=PMID:16280327, GO:0005829=Reactome:REACT_118777, GO:0005737=PMID:15082780, GO:0051092=PMID:14695475, GO:0042101=PMID:12154360, GO:0019900=PMID:17052756, GO:0042109=PMID:16647297, GO:0001772=GO_REF:0000019, GO:0051059=PMID:16280327, GO:0032449=PMID:15125833, GO:0006915=PMID:11466612, GO:0008022=PMID:11053425, GO:0043422=PMID:16280327, GO:0002250=PMID:16831874, GO:0006968=GO_REF:0000019, GO:0071260=PMID:19593445, GO:0042327=PMID:15125833} O95999 B-cell lymphoma/leukemia 10 protein 20110201 {GO:0005515=IPI, GO:0008219=IDA, GO:0043130=IDA, GO:0016064=IEA, GO:0042226=NAS, GO:0002020=IPI, GO:0043621=IPI, GO:0005764=IDA, GO:0042221=IDA, GO:0051259=IPI, GO:0002906=IDA, GO:0031398=IDA, GO:0051260=TAS, GO:0043123=IEP, GO:0031625=IPI, GO:0046696=IDA, GO:0032765=NAS, GO:0019901=IDA, GO:0003713=IDA, GO:0045416=IMP, GO:0001843=ISS, GO:0002224=IC, GO:0043234=IDA, GO:0019209=IDA, GO:0045087=IEP, GO:0050870=IEA, GO:0045121=IEA, GO:0045893=IDA, GO:0019899=IPI, GO:0008134=IPI, GO:0005881=IDA, GO:0050852=TAS, GO:0048471=IDA, GO:0005886=TAS, GO:0050856=IEA, GO:0002237=IEP, GO:0009620=IEA, GO:0005634=IDA, GO:0005829=TAS, GO:0005737=IDA, GO:0051092=IDA, GO:0042101=IDA, GO:0019900=IPI, GO:0042109=NAS, GO:0001772=IEA, GO:0051059=IDA, GO:0032449=NAS, GO:0006915=IDA, GO:0008022=IPI, GO:0043422=IPI, GO:0002250=TAS, GO:0006968=IEA, GO:0071260=IEP, GO:0042327=IDA} T cell receptor signaling pathway, adaptive immune response, apoptotic process, cell death, cellular defense response, cellular response to mechanical stimulus, immunoglobulin mediated immune response, innate immune response, interleukin-6 biosynthetic process, lymphotoxin A biosynthetic process, negative regulation of mature B cell apoptotic process, neural tube closure, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of T cell activation, positive regulation of interleukin-8 biosynthetic process, positive regulation of mast cell cytokine production, positive regulation of phosphorylation, positive regulation of protein ubiquitination, positive regulation of transcription, DNA-dependent, protein homooligomerization, protein oligomerization, regulation of T cell receptor signaling pathway, response to chemical stimulus, response to fungus, response to molecule of bacterial origin, toll-like receptor signaling pathway CBM complex, T cell receptor complex, cytoplasm, cytoplasmic microtubule, cytosol, immunological synapse, lipopolysaccharide receptor complex, lysosome, membrane raft, nucleus, perinuclear region of cytoplasm, plasma membrane, protein complex NF-kappaB binding, enzyme binding, kinase activator activity, kinase binding, protease binding, protein C-terminus binding, protein binding, protein kinase B binding, protein kinase binding, protein self-association, transcription coactivator activity, transcription factor binding, ubiquitin binding, ubiquitin protein ligase binding Human UniProtKB:Q9UDY8 BCL11A UniProtKB UniProtKB {GO:0030097=GO_REF:0000029, GO:0005737=GO_REF:0000029, GO:0006355=GO_REF:0000037, GO:0030217=GO_REF:0000019, GO:0016925=GO_REF:0000024, GO:0003714=GO_REF:0000019, GO:0030183=GO_REF:0000019, GO:0010629=GO_REF:0000019, GO:0005634=GO_REF:0000029, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q9H165 B-cell lymphoma/leukemia 11A protein 20100802 {GO:0030097=NAS, GO:0005737=NAS, GO:0006355=IEA, GO:0030217=IEA, GO:0016925=ISS, GO:0003714=IEA, GO:0030183=IEA, GO:0010629=IEA, GO:0005634=NAS, GO:0008270=IEA, GO:0003676=IEA, GO:0006351=IEA} B cell differentiation, T cell differentiation, hemopoiesis, negative regulation of gene expression, protein sumoylation, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus nucleic acid binding, transcription corepressor activity, zinc ion binding Human UniProtKB:Q9QYE3 BCL11B MGI UniProtKB {GO:0071678=GO_REF:0000019, GO:0003382=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0033077=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0033153=GO_REF:0000019, GO:0046632=GO_REF:0000019, GO:0010837=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0048538=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0000978=GO_REF:0000019, GO:0003334=GO_REF:0000019, GO:0043368=GO_REF:0000019, GO:0031077=GO_REF:0000019, GO:0019216=GO_REF:0000019, GO:0001077=GO_REF:0000019, GO:0045944=PMID:16809611, GO:0045664=GO_REF:0000019, GO:0021773=GO_REF:0000019, GO:0042475=GO_REF:0000019, GO:0043588=GO_REF:0000019, GO:0008270=GO_REF:0000002} Q9C0K0 B-cell lymphoma/leukemia 11B protein 20101118 {GO:0071678=IEA, GO:0003382=IEA, GO:0043066=IEA, GO:0033077=IEA, GO:0008285=IEA, GO:0033153=IEA, GO:0046632=IEA, GO:0010837=IEA, GO:0005634=IEA, GO:0048538=IEA, GO:0003676=IEA, GO:0000978=IEA, GO:0003334=IEA, GO:0043368=IEA, GO:0031077=IEA, GO:0019216=IEA, GO:0001077=IEA, GO:0045944=IMP, GO:0045664=IEA, GO:0021773=IEA, GO:0042475=IEA, GO:0043588=IEA, GO:0008270=IEA} T cell differentiation in thymus, T cell receptor V(D)J recombination, alpha-beta T cell differentiation, epithelial cell morphogenesis, keratinocyte development, negative regulation of apoptotic process, negative regulation of cell proliferation, odontogenesis of dentin-containing tooth, olfactory bulb axon guidance, positive T cell selection, positive regulation of transcription from RNA polymerase II promoter, post-embryonic camera-type eye development, regulation of keratinocyte proliferation, regulation of lipid metabolic process, regulation of neuron differentiation, skin development, striatal medium spiny neuron differentiation, thymus development nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, nucleic acid binding, zinc ion binding Human BCL2 BHF-UCL UniProtKB {GO:0005515=PMID:21454712, GO:0030308=GO_REF:0000019, GO:0030307=PMID:8022822, GO:0010523=GO_REF:0000019, GO:0045069=GO_REF:0000019, GO:0051402=PMID:16167175, GO:0009791=GO_REF:0000019, GO:0048599=GO_REF:0000019, GO:0031069=GO_REF:0000019, GO:0016337=GO_REF:0000019, GO:0051607=PMID:10620603, GO:1900740=Reactome:REACT_697, GO:0048589=GO_REF:0000019, GO:0018105=GO_REF:0000019, GO:0018107=GO_REF:0000019, GO:0014031=GO_REF:0000019, GO:0002326=GO_REF:0000019, GO:0033033=GO_REF:0000019, GO:0010332=GO_REF:0000019, GO:0031625=PMID:20889974, GO:0000209=PMID:16717086, GO:0002320=GO_REF:0000019, GO:0046982=PMID:9111042, GO:0071310=GO_REF:0000019, GO:0032469=GO_REF:0000019, GO:0009636=PMID:16307838, GO:2001244=Reactome:REACT_330, GO:0043085=GO_REF:0000019, GO:0001503=GO_REF:0000019, GO:0070059=PMID:15776018, GO:0045087=Reactome:REACT_6802, GO:0005789=GO_REF:0000039, GO:0016049=GO_REF:0000019, GO:0008134=GO_REF:0000019, GO:0050853=PMID:17875758, GO:0001782=GO_REF:0000019, GO:0005783=PMID:8402648, GO:0030890=PMID:17875758, GO:0005634=PMID:7896880, GO:0001836=PMID:9843949, GO:0005829=GO_REF:0000019, GO:0033138=GO_REF:0000019, GO:0048873=GO_REF:0000019, GO:0042100=PMID:1373874, GO:0051902=PMID:9027314, GO:0043209=GO_REF:0000019, GO:0006959=PMID:1908951, GO:0001101=GO_REF:0000019, GO:0007015=GO_REF:0000019, GO:0040018=GO_REF:0000019, GO:0051721=GO_REF:0000019, GO:0009314=PMID:15799693, GO:0046902=PMID:9843949, GO:0051434=PMID:9111042, GO:0042493=PMID:36599, GO:0046671=GO_REF:0000019, GO:0072593=GO_REF:0000019, GO:0006974=PMID:17875758, GO:0009605=GO_REF:0000019, GO:0016020=PMID:7896880, GO:0010224=GO_REF:0000019, GO:0015267=PMID:9219694, GO:0035094=PMID:12421819, GO:0001656=GO_REF:0000019, GO:0043496=PMID:9111042, GO:0008219=PMID:8022822, GO:0042542=GO_REF:0000019, GO:0043497=PMID:9111042, GO:0001658=GO_REF:0000019, GO:0033689=GO_REF:0000019, GO:0048538=GO_REF:0000019, GO:0048753=GO_REF:0000019, GO:0048536=GO_REF:0000019, GO:0002020=PMID:10620603, GO:0006808=GO_REF:0000019, GO:0042803=PMID:9111042, GO:0042802=PMID:18835031, GO:0043524=PMID:7546744, GO:0048743=GO_REF:0000019, GO:0010039=PMID:11264898, GO:0051924=PMID:8022822, GO:0001662=GO_REF:0000019, GO:0043029=GO_REF:0000019, GO:0033077=GO_REF:0000019, GO:0030336=GO_REF:0000019, GO:0007565=PMID:11530860, GO:0031965=PMID:8402648, GO:0010559=GO_REF:0000019, GO:0007569=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0048546=GO_REF:0000019, GO:0046930=PMID:9219694, GO:0045930=GO_REF:0000019, GO:0001952=GO_REF:0000019, GO:0006582=GO_REF:0000019, GO:0031103=GO_REF:0000019, GO:2001234=PMID:20097879, GO:0043375=GO_REF:0000019, GO:0005741=Reactome:REACT_75844, GO:0035872=Reactome:REACT_75913, GO:0032835=GO_REF:0000019, GO:0043583=GO_REF:0000019, GO:0014911=GO_REF:0000019, GO:0005739=PMID:7896880, GO:0001541=GO_REF:0000019, GO:0030279=GO_REF:0000019, GO:0005737=PMID:7546744, GO:0000082=GO_REF:0000019, GO:0031647=GO_REF:0000019, GO:0006470=GO_REF:0000019, GO:0035265=GO_REF:0000019, GO:0048041=GO_REF:0000019, GO:0022612=GO_REF:0000019, GO:0045636=GO_REF:0000019, GO:0034097=PMID:9184696, GO:0021747=GO_REF:0000019, GO:0043066=PMID:9219694, GO:0022898=PMID:9219694, GO:0051881=PMID:9843949, GO:0006915=Reactome:REACT_578, GO:0030318=GO_REF:0000019, GO:0014042=GO_REF:0000019, GO:0097193=Reactome:REACT_964, GO:0032848=PMID:10506221, GO:0003014=GO_REF:0000019, GO:0043565=PMID:12086670, GO:0008584=GO_REF:0000019} P10415 Apoptosis regulator Bcl-2 protein 20110325 {GO:0005515=IPI, GO:0030308=IEA, GO:0030307=IDA, GO:0010523=IEA, GO:0045069=IEA, GO:0051402=TAS, GO:0009791=IEA, GO:0048599=IEA, GO:0031069=IEA, GO:0016337=IEA, GO:0051607=IDA, GO:1900740=TAS, GO:0048589=IEA, GO:0018105=IEA, GO:0018107=IEA, GO:0014031=IEA, GO:0002326=IEA, GO:0033033=IEA, GO:0010332=IEA, GO:0031625=IPI, GO:0000209=IDA, GO:0002320=IEA, GO:0046982=IPI, GO:0071310=IEA, GO:0032469=IEA, GO:0009636=IDA, GO:2001244=TAS, GO:0043085=IEA, GO:0001503=IEA, GO:0070059=IDA, GO:0045087=TAS, GO:0005789=IEA, GO:0016049=IEA, GO:0008134=IEA, GO:0050853=IMP, GO:0001782=IEA, GO:0005783=IDA, GO:0030890=IMP, GO:0005634=IDA, GO:0001836=ISS, GO:0005829=IEA, GO:0033138=IEA, GO:0048873=IEA, GO:0042100=IDA, GO:0051902=TAS, GO:0043209=IEA, GO:0006959=TAS, GO:0001101=IEA, GO:0007015=IEA, GO:0040018=IEA, GO:0051721=IEA, GO:0009314=NAS, GO:0046902=ISS, GO:0051434=IPI, GO:0042493=IDA, GO:0046671=IEA, GO:0072593=IEA, GO:0006974=IMP, GO:0009605=IEA, GO:0016020=IDA, GO:0010224=IEA, GO:0015267=IDA, GO:0035094=IDA, GO:0001656=IEA, GO:0043496=IDA, GO:0008219=IDA, GO:0042542=IEA, GO:0043497=IDA, GO:0001658=IEA, GO:0033689=IEA, GO:0048538=IEA, GO:0048753=IEA, GO:0048536=IEA, GO:0002020=IDA, GO:0006808=IEA, GO:0042803=IPI, GO:0042802=IPI, GO:0043524=IDA, GO:0048743=IEA, GO:0010039=IDA, GO:0051924=IDA, GO:0001662=IEA, GO:0043029=IEA, GO:0033077=IEA, GO:0030336=IEA, GO:0007565=NAS, GO:0031965=IDA, GO:0010559=IEA, GO:0007569=IEA, GO:0051384=IEA, GO:0048546=IEA, GO:0046930=IDA, GO:0045930=IEA, GO:0001952=IEA, GO:0006582=IEA, GO:0031103=IEA, GO:2001234=IMP, GO:0043375=IEA, GO:0005741=TAS, GO:0035872=TAS, GO:0032835=IEA, GO:0043583=IEA, GO:0014911=IEA, GO:0005739=IDA, GO:0001541=IEA, GO:0030279=IEA, GO:0005737=IDA, GO:0000082=IEA, GO:0031647=IEA, GO:0006470=IEA, GO:0035265=IEA, GO:0048041=IEA, GO:0022612=IEA, GO:0045636=IEA, GO:0034097=IDA, GO:0021747=IEA, GO:0043066=IDA, GO:0022898=IDA, GO:0051881=ISS, GO:0006915=TAS, GO:0030318=IEA, GO:0014042=IEA, GO:0097193=TAS, GO:0032848=IDA, GO:0003014=IEA, GO:0043565=IDA, GO:0008584=IEA} B cell homeostasis, B cell lineage commitment, B cell proliferation, B cell receptor signaling pathway, CD8-positive, alpha-beta T cell lineage commitment, G1/S transition of mitotic cell cycle, T cell differentiation in thymus, T cell homeostasis, actin filament organization, apoptotic process, axon regeneration, behavioral fear response, branching involved in ureteric bud morphogenesis, cell aging, cell death, cell growth, cell-cell adhesion, cellular response to organic substance, cochlear nucleus development, defense response to virus, developmental growth, digestive tract morphogenesis, ear development, endoplasmic reticulum calcium ion homeostasis, female pregnancy, focal adhesion assembly, gland morphogenesis, glomerulus development, hair follicle morphogenesis, homeostasis of number of cells within a tissue, humoral immune response, innate immune response, intrinsic apoptotic signaling pathway, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, lymphoid progenitor cell differentiation, male gonad development, melanin metabolic process, melanocyte differentiation, mesenchymal cell development, metanephros development, negative regulation of apoptotic process, negative regulation of apoptotic signaling pathway, negative regulation of calcium ion transport into cytosol, negative regulation of cell growth, negative regulation of cell migration, negative regulation of cellular pH reduction, negative regulation of mitochondrial depolarization, negative regulation of mitotic cell cycle, negative regulation of myeloid cell apoptotic process, negative regulation of neuron apoptotic process, negative regulation of ossification, negative regulation of osteoblast proliferation, negative regulation of retinal cell programmed cell death, neuron apoptotic process, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, oocyte development, organ growth, ossification, ovarian follicle development, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, pigment granule organization, positive regulation of B cell proliferation, positive regulation of catalytic activity, positive regulation of cell growth, positive regulation of intrinsic apoptotic signaling pathway, positive regulation of melanocyte differentiation, positive regulation of multicellular organism growth, positive regulation of neuron maturation, positive regulation of peptidyl-serine phosphorylation, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, positive regulation of skeletal muscle fiber development, positive regulation of smooth muscle cell migration, post-embryonic development, protein dephosphorylation, protein polyubiquitination, reactive oxygen species metabolic process, regulation of calcium ion transport, regulation of cell-matrix adhesion, regulation of glycoprotein biosynthetic process, regulation of mitochondrial membrane permeability, regulation of mitochondrial membrane potential, regulation of nitrogen utilization, regulation of protein heterodimerization activity, regulation of protein homodimerization activity, regulation of protein stability, regulation of transmembrane transporter activity, regulation of viral genome replication, release of cytochrome c from mitochondria, renal system process, response to DNA damage stimulus, response to UV-B, response to acid, response to cytokine stimulus, response to drug, response to external stimulus, response to gamma radiation, response to glucocorticoid stimulus, response to hydrogen peroxide, response to iron ion, response to nicotine, response to radiation, response to toxic substance, spleen development, thymus development cytoplasm, cytosol, endoplasmic reticulum, endoplasmic reticulum membrane, membrane, mitochondrial outer membrane, mitochondrion, myelin sheath, nuclear membrane, nucleus, pore complex BH3 domain binding, channel activity, identical protein binding, protease binding, protein binding, protein heterodimerization activity, protein homodimerization activity, protein phosphatase 2A binding, sequence-specific DNA binding, transcription factor binding, ubiquitin protein ligase binding Human BCL2A1 HGNC UniProtKB {GO:0005515=PMID:10753914, GO:0005737=GO_REF:0000039, GO:0043066=GO_REF:0000002, GO:0006915=GO_REF:0000037} Q16548 Bcl-2-related protein A1 protein 20070302 {GO:0005515=IPI, GO:0005737=IEA, GO:0043066=IEA, GO:0006915=IEA} apoptotic process, negative regulation of apoptotic process cytoplasm protein binding Human UniProtKB:Q07812 BCL2L1 ENSEMBL UniProtKB {GO:0005515=PMID:19060904, GO:0007093=PMID:21840391, GO:0008284=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:0001836=GO_REF:0000019, GO:0005741=Reactome:REACT_75844, GO:0007283=GO_REF:0000019, GO:0071480=GO_REF:0000019, GO:0007281=GO_REF:0000019, GO:0035872=Reactome:REACT_75913, GO:0005829=GO_REF:0000019, GO:0005739=PMID:12011449, GO:0000910=PMID:21840391, GO:0043524=GO_REF:0000019, GO:0001541=GO_REF:0000019, GO:0005737=PMID:20673843, GO:0008637=PMID:9393856, GO:0090201=PMID:21041309, GO:0071230=GO_REF:0000019, GO:0097136=PMID:21199865, GO:0034097=PMID:9184696, GO:0046902=PMID:9843949, GO:0031965=GO_REF:0000039, GO:0043066=PMID:12011449, GO:0005813=PMID:21840391, GO:0031966=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0019901=PMID:21840391, GO:0046982=GO_REF:0000019, GO:0051881=PMID:9843949, GO:0071312=GO_REF:0000019, GO:0006915=Reactome:REACT_578, GO:2001244=Reactome:REACT_330, GO:0046898=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0097193=Reactome:REACT_964, GO:0009566=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0090005=PMID:21041309, GO:0016021=GO_REF:0000037, GO:0060154=GO_REF:0000019, GO:0040007=GO_REF:0000019, GO:0008584=GO_REF:0000019} Q9H1R6 Bcl-2-like protein 1 protein 20130413 {GO:0005515=IPI, GO:0007093=IMP, GO:0008284=IEA, GO:0008283=IEA, GO:0001836=IEA, GO:0005741=TAS, GO:0007283=IEA, GO:0071480=IEA, GO:0007281=IEA, GO:0035872=TAS, GO:0005829=IEA, GO:0005739=IDA, GO:0000910=IMP, GO:0043524=IEA, GO:0001541=IEA, GO:0005737=IDA, GO:0008637=TAS, GO:0090201=IC, GO:0071230=IEA, GO:0097136=IDA, GO:0034097=IDA, GO:0046902=IDA, GO:0031965=IEA, GO:0043066=IDA, GO:0005813=IDA, GO:0031966=IEA, GO:0043065=IEA, GO:0019901=IPI, GO:0046982=IEA, GO:0051881=IDA, GO:0071312=IEA, GO:0006915=TAS, GO:2001244=TAS, GO:0046898=IEA, GO:0001701=IEA, GO:0097193=TAS, GO:0009566=IEA, GO:0045087=TAS, GO:0090005=IDA, GO:0016021=IEA, GO:0060154=IEA, GO:0040007=IEA, GO:0008584=IEA} apoptotic mitochondrial changes, apoptotic process, cell proliferation, cellular process regulating host cell cycle in response to virus, cellular response to alkaloid, cellular response to amino acid stimulus, cellular response to gamma radiation, cytokinesis, fertilization, germ cell development, growth, in utero embryonic development, innate immune response, intrinsic apoptotic signaling pathway, male gonad development, mitotic cell cycle checkpoint, negative regulation of apoptotic process, negative regulation of establishment of protein localization to plasma membrane, negative regulation of neuron apoptotic process, negative regulation of release of cytochrome c from mitochondria, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, ovarian follicle development, positive regulation of apoptotic process, positive regulation of cell proliferation, positive regulation of intrinsic apoptotic signaling pathway, regulation of mitochondrial membrane permeability, regulation of mitochondrial membrane potential, release of cytochrome c from mitochondria, response to cycloheximide, response to cytokine stimulus, spermatogenesis Bcl-2 family protein complex, centrosome, cytoplasm, cytosol, integral to membrane, mitochondrial membrane, mitochondrial outer membrane, mitochondrion, nuclear membrane protein binding, protein heterodimerization activity, protein kinase binding Human Ensembl:ENSMUSP00000105445 BCL2L10 HGNC UniProtKB {GO:0005739=PMID:11278245, GO:0005515=PMID:11278245, GO:0031965=GO_REF:0000039, GO:0043066=PMID:11278245, GO:0016020=PMID:9878060, GO:0006919=PMID:9829980, GO:0007292=PMID:9878060, GO:0007283=PMID:9878060, GO:0016021=GO_REF:0000037, GO:0005829=PMID:11278245} Q9HD36 Bcl-2-like protein 10 protein 20070302 {GO:0005739=IDA, GO:0005515=IPI, GO:0031965=IEA, GO:0043066=IDA, GO:0016020=TAS, GO:0006919=TAS, GO:0007292=TAS, GO:0007283=TAS, GO:0016021=IEA, GO:0005829=IDA} activation of cysteine-type endopeptidase activity involved in apoptotic process, female gamete generation, negative regulation of apoptotic process, spermatogenesis cytosol, integral to membrane, membrane, mitochondrion, nuclear membrane protein binding Human BCL2L11 BHF-UCL UniProtKB {GO:0005515=PMID:23245996, GO:0008017=GO_REF:0000019, GO:0001783=GO_REF:0000019, GO:0034976=PMID:22761832, GO:0001782=GO_REF:0000019, GO:0005741=Reactome:REACT_21389, GO:0048538=GO_REF:0000019, GO:0030879=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0048536=GO_REF:0000019, GO:0005829=Reactome:REACT_13777, GO:0043583=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:1900740=Reactome:REACT_1650, GO:0043525=GO_REF:0000019, GO:0090200=PMID:21041309, GO:0042475=GO_REF:0000019, GO:0043029=GO_REF:0000019, GO:0002262=GO_REF:0000019, GO:0048066=GO_REF:0000019, GO:0032464=PMID:21041309, GO:0046620=GO_REF:0000019, GO:0048011=Reactome:REACT_13776, GO:0046982=GO_REF:0000019, GO:0001822=GO_REF:0000019, GO:0035148=GO_REF:0000019, GO:0048563=GO_REF:0000019, GO:0006915=Reactome:REACT_13638, GO:2001244=Reactome:REACT_330, GO:0006917=PMID:10381623, GO:0097190=Reactome:REACT_13720, GO:0001701=GO_REF:0000019, GO:0045787=GO_REF:0000019, GO:0097193=Reactome:REACT_964, GO:0012505=GO_REF:0000039, GO:0048070=GO_REF:0000019, GO:0007160=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0060154=GO_REF:0000019, GO:0008584=GO_REF:0000019, GO:0019898=GO_REF:0000019} O43521 Bcl-2-like protein 11 protein 20110317 {GO:0005515=IPI, GO:0008017=IEA, GO:0001783=IEA, GO:0034976=IDA, GO:0001782=IEA, GO:0005741=TAS, GO:0048538=IEA, GO:0030879=IEA, GO:0007283=IEA, GO:0048536=IEA, GO:0005829=TAS, GO:0043583=IEA, GO:0005739=IEA, GO:1900740=TAS, GO:0043525=IEA, GO:0090200=IGI, GO:0042475=IEA, GO:0043029=IEA, GO:0002262=IEA, GO:0048066=IEA, GO:0032464=IDA, GO:0046620=IEA, GO:0048011=TAS, GO:0046982=IEA, GO:0001822=IEA, GO:0035148=IEA, GO:0048563=IEA, GO:0006915=TAS, GO:2001244=TAS, GO:0006917=TAS, GO:0097190=TAS, GO:0001701=IEA, GO:0045787=IEA, GO:0097193=TAS, GO:0012505=IEA, GO:0048070=IEA, GO:0007160=IEA, GO:0007420=IEA, GO:0060154=IEA, GO:0008584=IEA, GO:0019898=IEA} B cell apoptotic process, B cell homeostasis, T cell homeostasis, apoptotic process, apoptotic signaling pathway, brain development, cell-matrix adhesion, cellular process regulating host cell cycle in response to virus, developmental pigmentation, ear development, in utero embryonic development, induction of apoptosis, intrinsic apoptotic signaling pathway, kidney development, male gonad development, mammary gland development, myeloid cell homeostasis, neurotrophin TRK receptor signaling pathway, odontogenesis of dentin-containing tooth, positive regulation of cell cycle, positive regulation of intrinsic apoptotic signaling pathway, positive regulation of neuron apoptotic process, positive regulation of protein homooligomerization, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, positive regulation of release of cytochrome c from mitochondria, post-embryonic organ morphogenesis, regulation of developmental pigmentation, regulation of organ growth, response to endoplasmic reticulum stress, spermatogenesis, spleen development, thymus development, tube formation cytosol, endomembrane system, extrinsic to membrane, mitochondrial outer membrane, mitochondrion microtubule binding, protein binding, protein heterodimerization activity Human UniProtKB:P70444 BCL2L12 UniProtKB UniProtKB {GO:0006915=GO_REF:0000037} Q9HB09 Bcl-2-like protein 12 protein 20130413 {GO:0006915=IEA} apoptotic process Human UniProtKB-KW:KW-0053 BCL2L13 UniProtKB UniProtKB {GO:0005739=PMID:11262395, GO:0031966=GO_REF:0000039, GO:0006919=PMID:11262395, GO:0005634=GO_REF:0000039, GO:0042981=GO_REF:0000002, GO:0006917=PMID:11262395, GO:0016021=PMID:11262395, GO:0008656=PMID:11262395} Q9BXK5 Bcl-2-like protein 13 protein 20040129 {GO:0005739=NAS, GO:0031966=IEA, GO:0006919=NAS, GO:0005634=IEA, GO:0042981=IEA, GO:0006917=NAS, GO:0016021=IDA, GO:0008656=NAS} activation of cysteine-type endopeptidase activity involved in apoptotic process, induction of apoptosis, regulation of apoptotic process integral to membrane, mitochondrial membrane, mitochondrion, nucleus cysteine-type endopeptidase activator activity involved in apoptotic process Human BCL2L14 HPA UniProtKB {GO:0005515=PMID:17280616, GO:0005737=GO_REF:0000052, GO:0019901=PMID:17280616, GO:0016020=GO_REF:0000037, GO:0043229=PMID:11054413, GO:0006915=PMID:17280616, GO:0042981=GO_REF:0000002, GO:0005829=PMID:11054413, GO:0012505=GO_REF:0000039} Q9BZR8 Apoptosis facilitator Bcl-2-like protein 14 protein 20110516 {GO:0005515=IPI, GO:0005737=IDA, GO:0019901=IPI, GO:0016020=IEA, GO:0043229=IDA, GO:0006915=IDA, GO:0042981=IEA, GO:0005829=IDA, GO:0012505=IEA} apoptotic process, regulation of apoptotic process cytoplasm, cytosol, endomembrane system, intracellular organelle, membrane protein binding, protein kinase binding Human BCL2L2 IntAct UniProtKB {GO:0005515=PMID:21199865, GO:0031966=GO_REF:0000039, GO:0006915=GO_REF:0000019, GO:0042981=GO_REF:0000002, GO:0007283=PMID:8761287, GO:0060011=GO_REF:0000019, GO:0005829=GO_REF:0000019} Q92843 Bcl-2-like protein 2 protein 20130415 {GO:0005515=IPI, GO:0031966=IEA, GO:0006915=IEA, GO:0042981=IEA, GO:0007283=TAS, GO:0060011=IEA, GO:0005829=IEA} Sertoli cell proliferation, apoptotic process, regulation of apoptotic process, spermatogenesis cytosol, mitochondrial membrane protein binding Human UniProtKB:Q07812 BCL2L2-PABPN1 InterPro UniProtKB {GO:0042981=GO_REF:0000002} G3V2X3 Protein BCL2L2-PABPN1 protein 20130413 {GO:0042981=IEA} regulation of apoptotic process Human InterPro:IPR002475|InterPro:IPR003093|InterPro:IPR013280|InterPro:IPR020717|InterPro:IPR020731|InterPro:IPR026298 BCL3 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0042345=PMID:8196632, GO:0048471=GO_REF:0000039, GO:0003700=GO_REF:0000019, GO:0007249=PMID:8196632, GO:0042088=GO_REF:0000019, GO:0005634=PMID:8196632, GO:0048536=GO_REF:0000019, GO:0005737=PMID:11387332, GO:0032996=PMID:16280327, GO:0030198=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0030674=PMID:16306601, GO:0033257=PMID:9407099, GO:0002467=GO_REF:0000019, GO:0042742=GO_REF:0000019, GO:0000060=PMID:16280327, GO:0032729=GO_REF:0000019, GO:0043066=PMID:16384933, GO:0030330=PMID:16384933, GO:0045415=PMID:16306601, GO:0002268=GO_REF:0000019, GO:0042536=GO_REF:0000019, GO:0042832=GO_REF:0000019, GO:0045727=PMID:16384933, GO:0042981=PMID:16732314, GO:0009615=PMID:16306601, GO:0003677=GO_REF:0000019, GO:0006974=PMID:16384933, GO:0006351=PMID:16306601, GO:0042771=PMID:16384933, GO:0043234=PMID:16280327, GO:0010225=PMID:16384933, GO:0051457=PMID:8196632, GO:0045064=GO_REF:0000019, GO:0051101=PMID:9407099, GO:0019730=GO_REF:0000019, GO:0045893=PMID:16384933, GO:0045082=GO_REF:0000019, GO:0045892=PMID:16306601, GO:0002315=GO_REF:0000019, GO:0008134=PMID:8196632, GO:0002455=GO_REF:0000019} P20749 B-cell lymphoma 3 protein protein 20130415 {GO:0005515=IPI, GO:0042345=IEP, GO:0048471=IEA, GO:0003700=IEA, GO:0007249=IDA, GO:0042088=IEA, GO:0005634=IDA, GO:0048536=IEA, GO:0005737=IDA, GO:0032996=IDA, GO:0030198=IEA, GO:0045944=IEA, GO:0030674=TAS, GO:0033257=IDA, GO:0002467=IEA, GO:0042742=IEA, GO:0000060=IMP, GO:0032729=IEA, GO:0043066=IDA, GO:0030330=IMP, GO:0045415=IMP, GO:0002268=IEA, GO:0042536=IEA, GO:0042832=IEA, GO:0045727=IMP, GO:0042981=IDA, GO:0009615=IDA, GO:0003677=IEA, GO:0006974=IDA, GO:0006351=IDA, GO:0042771=IMP, GO:0043234=IDA, GO:0010225=IDA, GO:0051457=NAS, GO:0045064=IEA, GO:0051101=IEP, GO:0019730=IEA, GO:0045893=IDA, GO:0045082=IEA, GO:0045892=IDA, GO:0002315=IEA, GO:0008134=IPI, GO:0002455=IEA} DNA damage response, signal transduction by p53 class mediator, I-kappaB kinase/NF-kappaB cascade, T-helper 1 type immune response, T-helper 2 cell differentiation, antimicrobial humoral response, defense response to bacterium, defense response to protozoan, extracellular matrix organization, follicular dendritic cell differentiation, germinal center formation, humoral immune response mediated by circulating immunoglobulin, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, maintenance of protein location in nucleus, marginal zone B cell differentiation, negative regulation of apoptotic process, negative regulation of interleukin-8 biosynthetic process, negative regulation of transcription, DNA-dependent, negative regulation of tumor necrosis factor biosynthetic process, positive regulation of interferon-gamma production, positive regulation of interleukin-10 biosynthetic process, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of translation, protein import into nucleus, translocation, regulation of DNA binding, regulation of NF-kappaB import into nucleus, regulation of apoptotic process, response to DNA damage stimulus, response to UV-C, response to virus, spleen development, transcription, DNA-dependent Bcl3-Bcl10 complex, Bcl3/NF-kappaB2 complex, cytoplasm, nucleus, perinuclear region of cytoplasm, protein complex DNA binding, protein binding, protein binding, bridging, sequence-specific DNA binding transcription factor activity, transcription factor binding Human UniProtKB:P56545 BCL6 HPA UniProtKB {GO:0005515=PMID:16147992, GO:0030308=PMID:10490843, GO:0003700=PMID:15577913, GO:0030036=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0030890=GO_REF:0000019, GO:0005657=PMID:10490843, GO:0035024=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0007283=GO_REF:0000019, GO:0007266=GO_REF:0000019, GO:0048294=GO_REF:0000019, GO:0042092=GO_REF:0000019, GO:0008104=GO_REF:0000019, GO:0043380=GO_REF:0000019, GO:0002829=GO_REF:0000019, GO:0002903=PMID:15577913, GO:0048821=GO_REF:0000019, GO:0030183=GO_REF:0000019, GO:0002467=GO_REF:0000019, GO:0032319=GO_REF:0000019, GO:0002634=PMID:7795255, GO:0000060=PMID:11821949, GO:0032764=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0043065=PMID:10490843, GO:0005730=GO_REF:0000052, GO:0050727=GO_REF:0000019, GO:0000122=PMID:11929873, GO:0006974=PMID:15577913, GO:0045749=PMID:10490843, GO:0006351=GO_REF:0000037, GO:0031490=GO_REF:0000019, GO:0043565=PMID:15577913, GO:0000902=GO_REF:0000019, GO:0045629=GO_REF:0000019, GO:0003682=PMID:12097386, GO:0050776=PMID:16455075, GO:0008270=GO_REF:0000002, GO:0045892=PMID:15577913, GO:0051272=GO_REF:0000019, GO:0001953=GO_REF:0000019} P41182 B-cell lymphoma 6 protein protein 20100326 {GO:0005515=IPI, GO:0030308=IDA, GO:0003700=IMP, GO:0030036=IEA, GO:0008285=IEA, GO:0030890=IEA, GO:0005657=IDA, GO:0035024=IEA, GO:0005634=IDA, GO:0007283=IEA, GO:0007266=IEA, GO:0048294=IEA, GO:0042092=IEA, GO:0008104=IEA, GO:0043380=IEA, GO:0002829=IEA, GO:0002903=NAS, GO:0048821=IEA, GO:0030183=IEA, GO:0002467=IEA, GO:0032319=IEA, GO:0002634=NAS, GO:0000060=IGI, GO:0032764=IEA, GO:0043066=IEA, GO:0043065=IDA, GO:0005730=IDA, GO:0050727=IEA, GO:0000122=IDA, GO:0006974=IDA, GO:0045749=NAS, GO:0006351=IEA, GO:0031490=IEA, GO:0043565=IDA, GO:0000902=IEA, GO:0045629=IEA, GO:0003682=IDA, GO:0050776=NAS, GO:0008270=IEA, GO:0045892=IMP, GO:0051272=IEA, GO:0001953=IEA} B cell differentiation, Rho protein signal transduction, actin cytoskeleton organization, cell morphogenesis, erythrocyte development, germinal center formation, negative regulation of B cell apoptotic process, negative regulation of Rho protein signal transduction, negative regulation of S phase of mitotic cell cycle, negative regulation of T-helper 2 cell differentiation, negative regulation of apoptotic process, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of cell-matrix adhesion, negative regulation of isotype switching to IgE isotypes, negative regulation of mast cell cytokine production, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, negative regulation of type 2 immune response, positive regulation of B cell proliferation, positive regulation of apoptotic process, positive regulation of cellular component movement, protein import into nucleus, translocation, protein localization, regulation of Rho GTPase activity, regulation of germinal center formation, regulation of immune response, regulation of inflammatory response, regulation of memory T cell differentiation, response to DNA damage stimulus, spermatogenesis, transcription, DNA-dependent, type 2 immune response nucleolus, nucleus, replication fork chromatin DNA binding, chromatin binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding NOT Human BCL6B UniProtKB UniProtKB {GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0000122=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000019} Q8N143 B-cell CLL/lymphoma 6 member B protein protein 20130413 {GO:0005634=IEA, GO:0008270=IEA, GO:0000122=IEA, GO:0003676=IEA, GO:0003677=IEA} negative regulation of transcription from RNA polymerase II promoter nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 BCL7A UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0045892=PMID:15897551} Q4VC05 B-cell CLL/lymphoma 7 protein family member A protein 20070622 {GO:0003674=ND, GO:0005575=ND, GO:0045892=NAS} negative regulation of transcription, DNA-dependent cellular_component molecular_function Human BCL7B UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003779=PMID:8605326, GO:0005575=GO_REF:0000015} Q9BQE9 B-cell CLL/lymphoma 7 protein family member B protein 20061106 {GO:0008150=ND, GO:0003779=NAS, GO:0005575=ND} biological_process cellular_component actin binding Human BCL7C UniProtKB UniProtKB {GO:0006915=GO_REF:0000037} Q8WUZ0 B-cell CLL/lymphoma 7 protein family member C protein 20130413 {GO:0006915=IEA} apoptotic process Human UniProtKB-KW:KW-0053 BCL9 BHF-UCL UniProtKB {GO:0005515=PMID:18498752, GO:0005737=GO_REF:0000019, GO:0008013=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0014908=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0017015=PMID:19328798, GO:0060070=GO_REF:0000019, GO:0035019=GO_REF:0000019} O00512 B-cell CLL/lymphoma 9 protein protein 20091029 {GO:0005515=IPI, GO:0005737=IEA, GO:0008013=IEA, GO:0045944=IEA, GO:0014908=IEA, GO:0005634=IEA, GO:0017015=IMP, GO:0060070=IEA, GO:0035019=IEA} canonical Wnt receptor signaling pathway, myotube differentiation involved in skeletal muscle regeneration, positive regulation of transcription from RNA polymerase II promoter, regulation of transforming growth factor beta receptor signaling pathway, somatic stem cell maintenance cytoplasm, nucleus beta-catenin binding, protein binding NOT Human BCL9L HPA UniProtKB {GO:0008013=PMID:15574752, GO:0045944=PMID:19328798, GO:0003713=PMID:19328798, GO:0022604=PMID:19328798, GO:0010718=PMID:19328798, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0035914=GO_REF:0000019, GO:0060070=GO_REF:0000019, GO:0035019=GO_REF:0000019, GO:0030512=PMID:19328798, GO:0006351=GO_REF:0000037} Q86UU0 B-cell CLL/lymphoma 9-like protein protein 20120912 {GO:0008013=IDA, GO:0045944=IMP, GO:0003713=NAS, GO:0022604=IMP, GO:0010718=IMP, GO:0005730=IDA, GO:0005634=IDA, GO:0035914=IEA, GO:0060070=IEA, GO:0035019=IEA, GO:0030512=IMP, GO:0006351=IEA} canonical Wnt receptor signaling pathway, negative regulation of transforming growth factor beta receptor signaling pathway, positive regulation of epithelial to mesenchymal transition, positive regulation of transcription from RNA polymerase II promoter, regulation of cell morphogenesis, skeletal muscle cell differentiation, somatic stem cell maintenance, transcription, DNA-dependent nucleolus, nucleus beta-catenin binding, transcription coactivator activity NOT Human BCLAF1 HPA UniProtKB {GO:0005515=PMID:15009215, GO:0005737=GO_REF:0000039, GO:0043065=PMID:10330179, GO:2001022=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006917=PMID:10330179, GO:0003677=PMID:10330179, GO:0045892=PMID:10330179, GO:0006351=GO_REF:0000037} Q9NYF8 Bcl-2-associated transcription factor 1 protein 20111111 {GO:0005515=IPI, GO:0005737=IEA, GO:0043065=IDA, GO:2001022=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006917=TAS, GO:0003677=IDA, GO:0045892=IDA, GO:0006351=IEA} induction of apoptosis, negative regulation of transcription, DNA-dependent, positive regulation of apoptotic process, positive regulation of response to DNA damage stimulus, transcription, DNA-dependent cytoplasm, nucleolus, nucleus DNA binding, protein binding NOT Human BCMO1 BHF-UCL UniProtKB {GO:0035238=PMID:15983114, GO:0004497=GO_REF:0000037, GO:0007603=Reactome:REACT_160125, GO:0042574=PMID:15983114, GO:0042572=GO_REF:0000041, GO:0001523=Reactome:REACT_24968, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_25117, GO:0003834=Reactome:REACT_25117} Q9HAY6 Beta,beta-carotene 15,15'-monooxygenase protein 20120626 {GO:0035238=NAS, GO:0004497=IEA, GO:0007603=TAS, GO:0042574=NAS, GO:0042572=IEA, GO:0001523=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0003834=TAS} phototransduction, visible light, retinal metabolic process, retinoid metabolic process, retinol metabolic process, vitamin A biosynthetic process cytosol beta-carotene 15,15'-monooxygenase activity, metal ion binding, monooxygenase activity Human BCOR IntAct UniProtKB {GO:0031519=PMID:16943429, GO:0005515=PMID:16943429, GO:0035518=PMID:16943429, GO:0000415=PMID:19578371, GO:0004842=PMID:16943429, GO:0044212=PMID:19578371, GO:0042826=PMID:10898795, GO:0003714=PMID:15878880, GO:0070171=PMID:19578371, GO:0005634=PMID:10898795, GO:0000122=PMID:19578371, GO:0030502=PMID:19578371, GO:0006351=GO_REF:0000037, GO:0065001=PMID:17517692, GO:0007507=PMID:17517692, GO:0031072=PMID:16943429, GO:0051572=PMID:19578371, GO:0042476=PMID:17517692, GO:0060021=PMID:17517692, GO:0045892=PMID:15878880, GO:0008134=PMID:10898795} Q6W2J9 BCL-6 corepressor protein 20130415 {GO:0031519=IDA, GO:0005515=IPI, GO:0035518=IDA, GO:0000415=IMP, GO:0004842=IDA, GO:0044212=IMP, GO:0042826=IPI, GO:0003714=IMP, GO:0070171=IMP, GO:0005634=IDA, GO:0000122=IMP, GO:0030502=IMP, GO:0006351=IEA, GO:0065001=IMP, GO:0007507=IMP, GO:0031072=IDA, GO:0051572=IMP, GO:0042476=IMP, GO:0060021=IMP, GO:0045892=IMP, GO:0008134=IPI} heart development, histone H2A monoubiquitination, negative regulation of bone mineralization, negative regulation of histone H3-K36 methylation, negative regulation of histone H3-K4 methylation, negative regulation of tooth mineralization, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, odontogenesis, palate development, specification of axis polarity, transcription, DNA-dependent PcG protein complex, nucleus heat shock protein binding, histone deacetylase binding, protein binding, transcription corepressor activity, transcription factor binding, transcription regulatory region DNA binding, ubiquitin-protein ligase activity Human UniProtKB:Q9BSM1 BCORL1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q5H9F3 BCL-6 corepressor-like protein 1 protein 20110516 {GO:0005737=IDA, GO:0006355=IEA, GO:0005886=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0006351=IEA, GO:0016568=IEA} chromatin modification, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleolus, nucleus, plasma membrane Human BCR IntAct UniProtKB {GO:0005515=PMID:22153077, GO:0043314=GO_REF:0000019, GO:0030036=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0007264=Reactome:REACT_11044, GO:0035023=GO_REF:0000002, GO:0005829=Reactome:REACT_121389, GO:0035556=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0050766=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0046777=GO_REF:0000019, GO:0016301=Reactome:REACT_120831, GO:0032496=GO_REF:0000019, GO:0050885=GO_REF:0000019, GO:0051726=GO_REF:0000019, GO:0005089=GO_REF:0000002, GO:0030675=GO_REF:0000019, GO:0051056=Reactome:REACT_11051, GO:0030336=GO_REF:0000019, GO:0042472=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0007165=PMID:1657398, GO:0007420=GO_REF:0000019, GO:0004674=GO_REF:0000037, GO:0050728=GO_REF:0000019, GO:0006468=PMID:1657398, GO:0004713=Reactome:REACT_121389, GO:0048008=GO_REF:0000019, GO:0019899=GO_REF:0000019, GO:0005096=PMID:1903516} P11274 Breakpoint cluster region protein protein 20130415 {GO:0005515=IPI, GO:0043314=IEA, GO:0030036=IEA, GO:0005886=IEA, GO:0007264=TAS, GO:0035023=IEA, GO:0005829=TAS, GO:0035556=IEA, GO:0005622=IEA, GO:0050766=IEA, GO:0005543=IEA, GO:0046777=IEA, GO:0016301=TAS, GO:0032496=IEA, GO:0050885=IEA, GO:0051726=IEA, GO:0005089=IEA, GO:0030675=IEA, GO:0051056=TAS, GO:0030336=IEA, GO:0042472=IEA, GO:0005524=IEA, GO:0007165=TAS, GO:0007420=IEA, GO:0004674=IEA, GO:0050728=IEA, GO:0006468=TAS, GO:0004713=TAS, GO:0048008=IEA, GO:0019899=IEA, GO:0005096=TAS} actin cytoskeleton organization, brain development, inner ear morphogenesis, intracellular signal transduction, negative regulation of cell migration, negative regulation of inflammatory response, negative regulation of neutrophil degranulation, neuromuscular process controlling balance, platelet-derived growth factor receptor signaling pathway, positive regulation of phagocytosis, protein autophosphorylation, protein phosphorylation, regulation of Rho protein signal transduction, regulation of cell cycle, regulation of small GTPase mediated signal transduction, response to lipopolysaccharide, signal transduction, small GTPase mediated signal transduction cytosol, intracellular, plasma membrane ATP binding, GTPase activator activity, Rac GTPase activator activity, Rho guanyl-nucleotide exchange factor activity, enzyme binding, kinase activity, phospholipid binding, protein binding, protein serine/threonine kinase activity, protein tyrosine kinase activity Human UniProtKB:Q9H2K2 BCS1L PINC UniProtKB {GO:0005515=PMID:18628306, GO:0033617=PMID:18628306, GO:0005739=PMID:18628306, GO:0032981=PMID:18628306, GO:0017111=GO_REF:0000002, GO:0034551=PMID:18628306, GO:0005750=PMID:9878253, GO:0007005=PMID:18628306, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q9Y276 Mitochondrial chaperone BCS1 protein 20030904 {GO:0005515=IPI, GO:0033617=IMP, GO:0005739=IDA, GO:0032981=IMP, GO:0017111=IEA, GO:0034551=IMP, GO:0005750=TAS, GO:0007005=IMP, GO:0016021=IEA, GO:0005524=IEA} mitochondrial respiratory chain complex I assembly, mitochondrial respiratory chain complex III assembly, mitochondrial respiratory chain complex IV assembly, mitochondrion organization integral to membrane, mitochondrial respiratory chain complex III, mitochondrion ATP binding, nucleoside-triphosphatase activity, protein binding Human BDH1 HPA UniProtKB {GO:0045471=GO_REF:0000019, GO:0005743=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0005739=GO_REF:0000052, GO:0042594=GO_REF:0000019, GO:0005543=GO_REF:0000019, GO:0005759=Reactome:REACT_1493, GO:0032355=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0051412=GO_REF:0000019, GO:0032868=GO_REF:0000019, GO:0060416=GO_REF:0000019, GO:0007584=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0009636=GO_REF:0000019, GO:0003858=Reactome:REACT_1493, GO:0001889=GO_REF:0000019, GO:0046952=Reactome:REACT_59, GO:0007420=GO_REF:0000019, GO:0046951=Reactome:REACT_1464, GO:0008152=GO_REF:0000029, GO:0046950=Reactome:REACT_1861, GO:0016491=GO_REF:0000038, GO:0060612=GO_REF:0000019, GO:0046686=GO_REF:0000019} Q02338 D-beta-hydroxybutyrate dehydrogenase, mitochondrial protein 20101115 {GO:0045471=IEA, GO:0005743=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0005739=IDA, GO:0042594=IEA, GO:0005543=IEA, GO:0005759=TAS, GO:0032355=IEA, GO:0044255=TAS, GO:0051412=IEA, GO:0032868=IEA, GO:0060416=IEA, GO:0007584=IEA, GO:0042493=IEA, GO:0005730=IDA, GO:0009636=IEA, GO:0003858=TAS, GO:0001889=IEA, GO:0046952=TAS, GO:0007420=IEA, GO:0046951=TAS, GO:0008152=TAS, GO:0046950=TAS, GO:0016491=IEA, GO:0060612=IEA, GO:0046686=IEA} adipose tissue development, brain development, cellular ketone body metabolic process, cellular lipid metabolic process, ketone body biosynthetic process, ketone body catabolic process, liver development, metabolic process, response to cadmium ion, response to corticosterone stimulus, response to drug, response to estradiol stimulus, response to ethanol, response to growth hormone stimulus, response to insulin stimulus, response to nutrient, response to starvation, response to toxic substance, small molecule metabolic process mitochondrial inner membrane, mitochondrial matrix, mitochondrion, nucleolus, nucleus 3-hydroxybutyrate dehydrogenase activity, oxidoreductase activity, phospholipid binding Human BDH2 HGNC UniProtKB {GO:0005739=PMID:16380372, GO:0005737=PMID:16380372, GO:0051287=PMID:16380372, GO:0006635=PMID:16380372, GO:0016491=GO_REF:0000002, GO:0003858=PMID:16380372, GO:0042168=GO_REF:0000024, GO:0008667=GO_REF:0000002, GO:0016628=GO_REF:0000024, GO:0055072=GO_REF:0000024, GO:0019290=GO_REF:0000024} Q9BUT1 3-hydroxybutyrate dehydrogenase type 2 protein 20060116 {GO:0005739=IDA, GO:0005737=IDA, GO:0051287=IDA, GO:0006635=IDA, GO:0016491=IEA, GO:0003858=IDA, GO:0042168=ISS, GO:0008667=IEA, GO:0016628=ISS, GO:0055072=ISS, GO:0019290=ISS} fatty acid beta-oxidation, heme metabolic process, iron ion homeostasis, siderophore biosynthetic process cytoplasm, mitochondrion 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity, 3-hydroxybutyrate dehydrogenase activity, NAD binding, oxidoreductase activity, oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor NOT Human BDKRB1 Reactome UniProtKB {GO:0043005=GO_REF:0000019, GO:0004947=GO_REF:0000019, GO:0042277=GO_REF:0000019, GO:0030308=GO_REF:0000019, GO:0005886=Reactome:REACT_22436, GO:0005783=PMID:9930991, GO:0006950=GO_REF:0000002, GO:0045776=GO_REF:0000019, GO:0007204=GO_REF:0000002, GO:0007205=GO_REF:0000019, GO:0019233=GO_REF:0000019, GO:0006954=GO_REF:0000019, GO:0016477=GO_REF:0000019, GO:0005887=PMID:8063797, GO:0002687=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0001933=GO_REF:0000019, GO:0016021=GO_REF:0000002, GO:0051281=GO_REF:0000019} P46663 B1 bradykinin receptor protein 20080728 {GO:0043005=IEA, GO:0004947=IEA, GO:0042277=IEA, GO:0030308=IEA, GO:0005886=TAS, GO:0005783=TAS, GO:0006950=IEA, GO:0045776=IEA, GO:0007204=IEA, GO:0007205=IEA, GO:0019233=IEA, GO:0006954=IEA, GO:0016477=IEA, GO:0005887=TAS, GO:0002687=IEA, GO:0032496=IEA, GO:0001933=IEA, GO:0016021=IEA, GO:0051281=IEA} cell migration, elevation of cytosolic calcium ion concentration, inflammatory response, negative regulation of blood pressure, negative regulation of cell growth, negative regulation of protein phosphorylation, positive regulation of leukocyte migration, positive regulation of release of sequestered calcium ion into cytosol, protein kinase C-activating G-protein coupled receptor signaling pathway, response to lipopolysaccharide, response to stress, sensory perception of pain endoplasmic reticulum, integral to membrane, integral to plasma membrane, neuron projection, plasma membrane bradykinin receptor activity, peptide binding Human BDKRB2 BHF-UCL UniProtKB {GO:0005515=PMID:18672896, GO:0004947=PMID:17077303, GO:0043066=GO_REF:0000019, GO:0009651=GO_REF:0000019, GO:0046982=PMID:10993080, GO:0005886=PMID:17077303, GO:0008015=PMID:7835885, GO:0002020=PMID:17077303, GO:0031702=PMID:10993080, GO:0007204=GO_REF:0000002, GO:0019229=PMID:17077303, GO:0006939=PMID:17077303, GO:0006954=PMID:17077303, GO:0007186=PMID:1314587, GO:0005887=PMID:7916737, GO:0004435=PMID:8302267, GO:0033137=GO_REF:0000019, GO:0043114=PMID:17077303, GO:0007169=PMID:10653985, GO:0007166=PMID:7916737, GO:0050482=PMID:17077303, GO:0005768=PMID:17077303} P30411 B2 bradykinin receptor protein 20080519 {GO:0005515=IPI, GO:0004947=IDA, GO:0043066=IEA, GO:0009651=IEA, GO:0046982=IPI, GO:0005886=IDA, GO:0008015=NAS, GO:0002020=IPI, GO:0031702=IPI, GO:0007204=IEA, GO:0019229=IC, GO:0006939=IC, GO:0006954=IC, GO:0007186=TAS, GO:0005887=TAS, GO:0004435=TAS, GO:0033137=IEA, GO:0043114=IC, GO:0007169=TAS, GO:0007166=TAS, GO:0050482=IDA, GO:0005768=IDA} G-protein coupled receptor signaling pathway, arachidonic acid secretion, blood circulation, cell surface receptor signaling pathway, elevation of cytosolic calcium ion concentration, inflammatory response, negative regulation of apoptotic process, negative regulation of peptidyl-serine phosphorylation, regulation of vascular permeability, regulation of vasoconstriction, response to salt stress, smooth muscle contraction, transmembrane receptor protein tyrosine kinase signaling pathway endosome, integral to plasma membrane, plasma membrane bradykinin receptor activity, phosphatidylinositol phospholipase C activity, protease binding, protein binding, protein heterodimerization activity, type 1 angiotensin receptor binding Human UniProtKB:P30556 BDNF UniProtKB UniProtKB {GO:0007631=GO_REF:0000019, GO:0001657=GO_REF:0000019, GO:0048471=GO_REF:0000024, GO:0008038=GO_REF:0000019, GO:0033189=GO_REF:0000019, GO:0019222=GO_REF:0000019, GO:0021675=GO_REF:0000019, GO:0007406=GO_REF:0000019, GO:0014076=GO_REF:0000019, GO:0042596=GO_REF:0000019, GO:0005737=GO_REF:0000024, GO:0007412=GO_REF:0000019, GO:0043524=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0007611=GO_REF:0000019, GO:0006120=GO_REF:0000019, GO:0072347=GO_REF:0000019, GO:0009725=GO_REF:0000019, GO:0051965=PMID:19036963, GO:0001666=GO_REF:0000019, GO:0048839=GO_REF:0000019, GO:0042490=GO_REF:0000019, GO:0005169=GO_REF:0000019, GO:0060079=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0002544=GO_REF:0000019, GO:0014047=GO_REF:0000019, GO:0016358=GO_REF:0000019, GO:0007399=PMID:2236018, GO:0008021=GO_REF:0000019, GO:0045843=GO_REF:0000019, GO:0045666=GO_REF:0000019, GO:0055093=GO_REF:0000019, GO:0048172=GO_REF:0000019, GO:0008083=GO_REF:0000038, GO:0046668=GO_REF:0000019, GO:0048170=GO_REF:0000019} Q6YNR1 Brain-derived neurotrophic factor BDNF7 protein 20130413 {GO:0007631=IEA, GO:0001657=IEA, GO:0048471=ISS, GO:0008038=IEA, GO:0033189=IEA, GO:0019222=IEA, GO:0021675=IEA, GO:0007406=IEA, GO:0014076=IEA, GO:0042596=IEA, GO:0005737=ISS, GO:0007412=IEA, GO:0043524=IEA, GO:0007411=IEA, GO:0007611=IEA, GO:0006120=IEA, GO:0072347=IEA, GO:0009725=IEA, GO:0051965=IDA, GO:0001666=IEA, GO:0048839=IEA, GO:0042490=IEA, GO:0005169=IEA, GO:0060079=IEA, GO:0005576=IEA, GO:0002544=IEA, GO:0014047=IEA, GO:0016358=IEA, GO:0007399=TAS, GO:0008021=IEA, GO:0045843=IEA, GO:0045666=IEA, GO:0055093=IEA, GO:0048172=IEA, GO:0008083=IEA, GO:0046668=IEA, GO:0048170=IEA} axon guidance, axon target recognition, chronic inflammatory response, dendrite development, fear response, feeding behavior, glutamate secretion, inner ear development, learning or memory, mechanoreceptor differentiation, mitochondrial electron transport, NADH to ubiquinone, negative regulation of neuroblast proliferation, negative regulation of neuron apoptotic process, negative regulation of striated muscle tissue development, nerve development, nervous system development, neuron recognition, positive regulation of long-term neuronal synaptic plasticity, positive regulation of neuron differentiation, positive regulation of synapse assembly, regulation of excitatory postsynaptic membrane potential, regulation of metabolic process, regulation of retinal cell programmed cell death, regulation of short-term neuronal synaptic plasticity, response to anesthetic, response to fluoxetine, response to hormone stimulus, response to hyperoxia, response to hypoxia, response to vitamin A, ureteric bud development cytoplasm, extracellular region, perinuclear region of cytoplasm, synaptic vesicle growth factor activity, neurotrophin TRKB receptor binding Human UniProtKB-KW:KW-0339 BDP1 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000037, GO:0003682=GO_REF:0000002, GO:0005654=Reactome:REACT_1779, GO:0006383=Reactome:REACT_1371, GO:0003677=GO_REF:0000002} A6H8Y1 Transcription factor TFIIIB component B'' homolog protein 20130213 {GO:0010467=TAS, GO:0006355=IEA, GO:0003682=IEA, GO:0005654=TAS, GO:0006383=TAS, GO:0003677=IEA} gene expression, regulation of transcription, DNA-dependent, transcription from RNA polymerase III promoter nucleoplasm DNA binding, chromatin binding Human BEAN1 UniProtKB UniProtKB {GO:0008219=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q3B7T3 Protein BEAN1 protein 20130413 {GO:0008219=IEA, GO:0016021=IEA} cell death integral to membrane Human UniProtKB-KW:KW-0812 BECN1 IntAct UniProtKB {GO:0005802=GO_REF:0000019, GO:0005515=PMID:21241894, GO:0008285=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0000910=PMID:20208530, GO:0051607=GO_REF:0000037, GO:0048666=GO_REF:0000019, GO:0033197=GO_REF:0000019, GO:0071275=GO_REF:0000019, GO:0000045=GO_REF:0000019, GO:0016239=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0043066=PMID:9765397, GO:0005794=GO_REF:0000039, GO:0042493=GO_REF:0000019, GO:0006914=GO_REF:0000002, GO:0050435=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0007049=GO_REF:0000037, GO:0006968=PMID:9765397, GO:0016020=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0016023=GO_REF:0000019, GO:0007040=GO_REF:0000019} Q14457 Beclin-1 protein 20130415 {GO:0005802=IEA, GO:0005515=IPI, GO:0008285=IEA, GO:0005634=IEA, GO:0030425=IEA, GO:0000910=IMP, GO:0051607=IEA, GO:0048666=IEA, GO:0033197=IEA, GO:0071275=IEA, GO:0000045=IEA, GO:0016239=IEA, GO:0001666=IEA, GO:0043066=TAS, GO:0005794=IEA, GO:0042493=IEA, GO:0006914=IEA, GO:0050435=IEA, GO:0043234=IEA, GO:0007049=IEA, GO:0006968=TAS, GO:0016020=IEA, GO:0019048=IEA, GO:0016023=IEA, GO:0007040=IEA} autophagic vacuole assembly, autophagy, beta-amyloid metabolic process, cell cycle, cellular defense response, cellular response to aluminum ion, cytokinesis, defense response to virus, lysosome organization, negative regulation of apoptotic process, negative regulation of cell proliferation, neuron development, positive regulation of macroautophagy, response to drug, response to hypoxia, response to vitamin E, virus-host interaction Golgi apparatus, cytoplasmic membrane-bounded vesicle, dendrite, membrane, nucleus, protein complex, trans-Golgi network protein binding Human UniProtKB:Q8IYI6 BEGAIN IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0005737=GO_REF:0000039, GO:0016020=GO_REF:0000039, GO:0016301=GO_REF:0000038, GO:0043025=GO_REF:0000019, GO:0030425=GO_REF:0000019} Q9BUH8 Brain-enriched guanylate kinase-associated protein protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0016020=IEA, GO:0016301=IEA, GO:0043025=IEA, GO:0030425=IEA} cytoplasm, dendrite, membrane, neuronal cell body kinase activity, protein binding Human UniProtKB:P28749 BEND2 null null {} null null null null {} null null null BEND3 null null {} null null null null {} null null null BEND5 ENSEMBL UniProtKB {GO:0005794=GO_REF:0000019} Q7L4P6 BEN domain-containing protein 5 protein 20130413 {GO:0005794=IEA} Golgi apparatus Human Ensembl:ENSMUSP00000030274 BEND7 IntAct UniProtKB {GO:0005515=PMID:19060904} Q8N7W2 BEN domain-containing protein 7 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:Q9GZT8 BEST1 HGNC UniProtKB {GO:0030321=PMID:17003041, GO:0006821=PMID:17003041, GO:0005886=Reactome:REACT_160220, GO:0034707=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0005254=PMID:17003041, GO:0005829=PMID:17003041, GO:0016323=PMID:19853238, GO:0034220=Reactome:REACT_25300, GO:0016020=PMID:10737974, GO:0050908=GO_REF:0000019, GO:0051924=GO_REF:0000019, GO:0016021=PMID:10737974, GO:0007601=PMID:9662395} O76090 Bestrophin-1 protein 20071022 {GO:0030321=IDA, GO:0006821=IDA, GO:0005886=TAS, GO:0034707=IEA, GO:0055085=TAS, GO:0005254=IDA, GO:0005829=TAS, GO:0016323=IDA, GO:0034220=TAS, GO:0016020=TAS, GO:0050908=IEA, GO:0051924=IEA, GO:0016021=TAS, GO:0007601=TAS} chloride transport, detection of light stimulus involved in visual perception, ion transmembrane transport, regulation of calcium ion transport, transepithelial chloride transport, transmembrane transport, visual perception basolateral plasma membrane, chloride channel complex, cytosol, integral to membrane, membrane, plasma membrane chloride channel activity Human BEST4 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005886=GO_REF:0000039, GO:0034707=GO_REF:0000037, GO:0005254=GO_REF:0000037} Q8NFU0 Bestrophin-4 protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0005886=IEA, GO:0034707=IEA, GO:0005254=IEA} biological_process chloride channel complex, plasma membrane chloride channel activity, molecular_function Human BET1 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0006888=GO_REF:0000019, GO:0005801=GO_REF:0000019, GO:0000139=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0031985=GO_REF:0000019, GO:0048280=GO_REF:0000019, GO:0016021=GO_REF:0000019, GO:0015031=GO_REF:0000037} O15155 BET1 homolog protein 20130415 {GO:0005515=IPI, GO:0006888=IEA, GO:0005801=IEA, GO:0000139=IEA, GO:0005789=IEA, GO:0031985=IEA, GO:0048280=IEA, GO:0016021=IEA, GO:0015031=IEA} ER to Golgi vesicle-mediated transport, protein transport, vesicle fusion with Golgi apparatus Golgi cisterna, Golgi membrane, cis-Golgi network, endoplasmic reticulum membrane, integral to membrane protein binding Human UniProtKB:Q8N6Y0 BET1L HPA UniProtKB {GO:0005484=PMID:15215310, GO:0030173=GO_REF:0000019, GO:0005794=GO_REF:0000052, GO:0005795=GO_REF:0000019, GO:0042147=PMID:15215310, GO:0031201=PMID:15215310, GO:0005634=GO_REF:0000052, GO:0015031=GO_REF:0000037, GO:0005768=PMID:15215310} Q9NYM9 BET1-like protein protein 20110516 {GO:0005484=IDA, GO:0030173=IEA, GO:0005794=IDA, GO:0005795=IEA, GO:0042147=IDA, GO:0031201=TAS, GO:0005634=IDA, GO:0015031=IEA, GO:0005768=IDA} protein transport, retrograde transport, endosome to Golgi Golgi apparatus, Golgi stack, SNARE complex, endosome, integral to Golgi membrane, nucleus SNAP receptor activity Human BET3L UniProtKB UniProtKB {GO:0005794=GO_REF:0000039, GO:0005783=GO_REF:0000039, GO:0016192=GO_REF:0000037} Q5T215 Trafficking protein particle complex subunit 3-like protein protein 20130413 {GO:0005794=IEA, GO:0005783=IEA, GO:0016192=IEA} vesicle-mediated transport Golgi apparatus, endoplasmic reticulum Human UniProtKB-SubCell:SL-0132 BEX1 BHF-UCL UniProtKB {GO:0005667=PMID:16314316, GO:0001102=PMID:16314316, GO:0051091=PMID:16314316, GO:0005737=GO_REF:0000039, GO:0045944=PMID:16314316, GO:0030154=GO_REF:0000037, GO:0007399=GO_REF:0000037} Q9HBH7 Protein BEX1 protein 20111208 {GO:0005667=IDA, GO:0001102=IPI, GO:0051091=IDA, GO:0005737=IEA, GO:0045944=IDA, GO:0030154=IEA, GO:0007399=IEA} cell differentiation, nervous system development, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter cytoplasm, transcription factor complex RNA polymerase II activating transcription factor binding Human BEX2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0007049=GO_REF:0000037, GO:0051726=PMID:19711341, GO:0006915=GO_REF:0000037, GO:0042981=PMID:19711341, GO:0005634=GO_REF:0000039} Q9BXY8 Protein BEX2 protein 20100201 {GO:0005737=IEA, GO:0007049=IEA, GO:0051726=IDA, GO:0006915=IEA, GO:0042981=IDA, GO:0005634=IEA} apoptotic process, cell cycle, regulation of apoptotic process, regulation of cell cycle cytoplasm, nucleus Human BEX4 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039} Q9NWD9 Protein BEX4 protein 20130413 {GO:0005737=IEA, GO:0005634=IEA} cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 BFAR MGI UniProtKB {GO:0043066=PMID:10716992, GO:0016020=PMID:10716992, GO:0005887=PMID:10716992, GO:0005198=PMID:10716992, GO:0005789=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0008270=GO_REF:0000002} Q9NZS9 Bifunctional apoptosis regulator protein 20060110 {GO:0043066=IDA, GO:0016020=IDA, GO:0005887=TAS, GO:0005198=TAS, GO:0005789=IEA, GO:0006915=IEA, GO:0008270=IEA} apoptotic process, negative regulation of apoptotic process endoplasmic reticulum membrane, integral to plasma membrane, membrane structural molecule activity, zinc ion binding Human BFSP1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005882=GO_REF:0000019, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0005212=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0070307=GO_REF:0000019, GO:0005200=PMID:9628810, GO:0048469=GO_REF:0000019, GO:0015629=GO_REF:0000052} Q12934 Filensin protein 20111111 {GO:0005739=IDA, GO:0005882=IEA, GO:0008150=ND, GO:0005737=IDA, GO:0005212=IEA, GO:0005886=IDA, GO:0070307=IEA, GO:0005200=TAS, GO:0048469=IEA, GO:0015629=IDA} biological_process, cell maturation, lens fiber cell development actin cytoskeleton, cytoplasm, intermediate filament, mitochondrion, plasma membrane structural constituent of cytoskeleton, structural constituent of eye lens Human BFSP2 HPA UniProtKB {GO:0005882=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0005212=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0070307=GO_REF:0000019, GO:0045104=GO_REF:0000019, GO:0005200=PMID:9628810, GO:0048469=GO_REF:0000019, GO:0007601=GO_REF:0000037, GO:0050896=GO_REF:0000037} Q13515 Phakinin protein 20110516 {GO:0005882=IEA, GO:0005737=IDA, GO:0005212=IEA, GO:0005886=IDA, GO:0070307=IEA, GO:0045104=IEA, GO:0005200=TAS, GO:0048469=IEA, GO:0007601=IEA, GO:0050896=IEA} cell maturation, intermediate filament cytoskeleton organization, lens fiber cell development, response to stimulus, visual perception cytoplasm, intermediate filament, plasma membrane structural constituent of cytoskeleton, structural constituent of eye lens Human BGLAP BHF-UCL UniProtKB {GO:0043627=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0045124=PMID:10486212, GO:0033280=PMID:17023519, GO:0030282=PMID:10486212, GO:0010043=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0033594=GO_REF:0000019, GO:0071305=GO_REF:0000019, GO:0046848=PMID:10486212, GO:0042476=PMID:11856645, GO:0043204=GO_REF:0000019, GO:0008147=PMID:12467198, GO:0007155=PMID:12202187, GO:0005791=GO_REF:0000019, GO:0014823=GO_REF:0000019, GO:0030500=GO_REF:0000002, GO:0005794=GO_REF:0000019, GO:0007569=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0031988=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0005576=PMID:11856645, GO:0051384=GO_REF:0000019, GO:0045670=PMID:10486212, GO:0033574=GO_REF:0000019, GO:0001649=PMID:17023519, GO:0009612=GO_REF:0000019, GO:0060348=GO_REF:0000019, GO:0001501=PMID:10865224, GO:0002076=GO_REF:0000019, GO:0071363=GO_REF:0000019, GO:0009629=GO_REF:0000019, GO:0005198=PMID:10486212, GO:0032571=GO_REF:0000019} P02818 Osteocalcin protein 20090507 {GO:0043627=IEA, GO:0045471=IEA, GO:0045124=NAS, GO:0033280=IEP, GO:0030282=NAS, GO:0010043=IEA, GO:0005615=IEA, GO:0030425=IEA, GO:0033594=IEA, GO:0071305=IEA, GO:0046848=NAS, GO:0042476=NAS, GO:0043204=IEA, GO:0008147=NAS, GO:0007155=NAS, GO:0005791=IEA, GO:0014823=IEA, GO:0030500=IEA, GO:0005794=IEA, GO:0007569=IEA, GO:0042493=IEA, GO:0031988=IEA, GO:0005509=IEA, GO:0005576=NAS, GO:0051384=IEA, GO:0045670=NAS, GO:0033574=IEA, GO:0001649=IEP, GO:0009612=IEA, GO:0060348=IEA, GO:0001501=TAS, GO:0002076=IEA, GO:0071363=IEA, GO:0009629=IEA, GO:0005198=NAS, GO:0032571=IEA} bone development, bone mineralization, cell adhesion, cell aging, cellular response to growth factor stimulus, cellular response to vitamin D, odontogenesis, osteoblast development, osteoblast differentiation, regulation of bone mineralization, regulation of bone resorption, regulation of osteoclast differentiation, response to activity, response to drug, response to estrogen stimulus, response to ethanol, response to glucocorticoid stimulus, response to gravity, response to hydroxyisoflavone, response to mechanical stimulus, response to testosterone stimulus, response to vitamin D, response to vitamin K, response to zinc ion, skeletal system development Golgi apparatus, dendrite, extracellular region, extracellular space, membrane-bounded vesicle, perikaryon, rough endoplasmic reticulum calcium ion binding, hydroxyapatite binding, structural constituent of bone, structural molecule activity Human BGN BHF-UCL UniProtKB {GO:0030133=GO_REF:0000054, GO:0019800=GO_REF:0000019, GO:0009986=PMID:2212616, GO:0005975=Reactome:REACT_474, GO:0005796=Reactome:REACT_121341, GO:0050840=GO_REF:0000019, GO:0005578=PMID:1860845, GO:0005576=Reactome:REACT_121341, GO:0044281=Reactome:REACT_111217, GO:0005539=GO_REF:0000019, GO:0030208=Reactome:REACT_120800, GO:0031012=PMID:22261194, GO:0042383=GO_REF:0000019, GO:0030207=Reactome:REACT_120888, GO:0008150=GO_REF:0000015, GO:0030206=Reactome:REACT_120989, GO:0001974=GO_REF:0000019, GO:0044424=GO_REF:0000019, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408, GO:0043202=Reactome:REACT_121272, GO:0005201=PMID:1860845} P21810 Biglycan protein 20120228 {GO:0030133=IDA, GO:0019800=IEA, GO:0009986=IDA, GO:0005975=TAS, GO:0005796=TAS, GO:0050840=IEA, GO:0005578=NAS, GO:0005576=TAS, GO:0044281=TAS, GO:0005539=IEA, GO:0030208=TAS, GO:0031012=ISS, GO:0042383=IEA, GO:0030207=TAS, GO:0008150=ND, GO:0030206=TAS, GO:0001974=IEA, GO:0044424=IEA, GO:0030204=TAS, GO:0030203=TAS, GO:0043202=TAS, GO:0005201=NAS} biological_process, blood vessel remodeling, carbohydrate metabolic process, chondroitin sulfate biosynthetic process, chondroitin sulfate catabolic process, chondroitin sulfate metabolic process, dermatan sulfate biosynthetic process, glycosaminoglycan metabolic process, peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan, small molecule metabolic process Golgi lumen, cell surface, extracellular matrix, extracellular region, intracellular part, lysosomal lumen, proteinaceous extracellular matrix, sarcolemma, transport vesicle extracellular matrix binding, extracellular matrix structural constituent, glycosaminoglycan binding colocalizes_with Human UniProtKB:Q9GKQ6 BHLHA15 UniProtKB UniProtKB {GO:0019722=GO_REF:0000019, GO:0048312=GO_REF:0000019, GO:0006851=GO_REF:0000019, GO:0007267=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0042593=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0042803=GO_REF:0000019, GO:0007186=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0007030=GO_REF:0000019, GO:0048469=GO_REF:0000019} Q7RTS1 Class A basic helix-loop-helix protein 15 protein 20130413 {GO:0019722=IEA, GO:0048312=IEA, GO:0006851=IEA, GO:0007267=IEA, GO:0005634=IEA, GO:0042593=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0042803=IEA, GO:0007186=IEA, GO:0045944=IEA, GO:0007030=IEA, GO:0048469=IEA} G-protein coupled receptor signaling pathway, Golgi organization, calcium-mediated signaling, cell maturation, cell-cell signaling, glucose homeostasis, intracellular distribution of mitochondria, mitochondrial calcium ion transport, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding, protein homodimerization activity Human UniProtKB-SubCell:SL-0191 BHLHB9 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039} Q6PI77 Protein BHLHb9 protein 20130413 {GO:0005737=IEA, GO:0005634=IEA} cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 BHLHE40 GOC UniProtKB {GO:0005515=PMID:11278694, GO:0001191=PMID:18411297, GO:0001102=GO_REF:0000024, GO:0006355=PMID:9240428, GO:0005794=GO_REF:0000052, GO:0003700=PMID:9240428, GO:0006366=PMID:12397359, GO:0046982=PMID:15193144, GO:0003705=GO_REF:0000024, GO:0000981=PMID:12397359, GO:0019904=PMID:15560782, GO:0005730=GO_REF:0000052, GO:0043426=GO_REF:0000024, GO:0043425=PMID:15193144, GO:0005634=GO_REF:0000052, GO:0070888=PMID:15193144, GO:0000122=PMID:12397359, GO:0032922=PMID:18411297, GO:0043433=PMID:18411297, GO:0042803=PMID:15560782, GO:0001078=PMID:15193144, GO:0043153=PMID:18411297} O14503 Class E basic helix-loop-helix protein 40 protein 20130413 {GO:0005515=IPI, GO:0001191=IDA, GO:0001102=ISS, GO:0006355=NAS, GO:0005794=IDA, GO:0003700=NAS, GO:0006366=IDA, GO:0046982=IPI, GO:0003705=ISS, GO:0000981=IDA, GO:0019904=IPI, GO:0005730=IDA, GO:0043426=ISS, GO:0043425=IPI, GO:0005634=IDA, GO:0070888=IDA, GO:0000122=IDA, GO:0032922=IDA, GO:0043433=IDA, GO:0042803=IDA, GO:0001078=IDA, GO:0043153=ISS} circadian regulation of gene expression, entrainment of circadian clock by photoperiod, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter Golgi apparatus, nucleolus, nucleus E-box binding, MRF binding, RNA polymerase II activating transcription factor binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription, bHLH transcription factor binding, protein binding, protein domain specific binding, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity Human BHLHE41 BHF-UCL UniProtKB {GO:0001191=GO_REF:0000024, GO:0001102=GO_REF:0000024, GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000029, GO:0046982=PMID:15193144, GO:0042826=GO_REF:0000024, GO:0008283=PMID:11162494, GO:0003705=GO_REF:0000024, GO:0043426=GO_REF:0000024, GO:0043425=PMID:15193144, GO:0005634=GO_REF:0000029, GO:0070888=PMID:15193144, GO:0000122=PMID:14672706, GO:0010832=GO_REF:0000024, GO:0000978=GO_REF:0000024, GO:0042803=GO_REF:0000024, GO:0032922=GO_REF:0000019, GO:0030154=PMID:11162494, GO:0001078=GO_REF:0000024, GO:0010944=GO_REF:0000024, GO:0009887=PMID:11162494} Q9C0J9 Class E basic helix-loop-helix protein 41 protein 20120613 {GO:0001191=ISS, GO:0001102=ISS, GO:0006355=NAS, GO:0003700=NAS, GO:0046982=IPI, GO:0042826=ISS, GO:0008283=NAS, GO:0003705=ISS, GO:0043426=ISS, GO:0043425=IPI, GO:0005634=NAS, GO:0070888=IDA, GO:0000122=IDA, GO:0010832=ISS, GO:0000978=ISS, GO:0042803=ISS, GO:0032922=IEA, GO:0030154=NAS, GO:0001078=ISS, GO:0010944=ISS, GO:0009887=NAS} cell differentiation, cell proliferation, circadian regulation of gene expression, negative regulation of myotube differentiation, negative regulation of transcription by competitive promoter binding, negative regulation of transcription from RNA polymerase II promoter, organ morphogenesis, regulation of transcription, DNA-dependent nucleus E-box binding, MRF binding, RNA polymerase II activating transcription factor binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription, bHLH transcription factor binding, histone deacetylase binding, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding transcription factor activity Human UniProtKB:O14503 BHMT HPA UniProtKB {GO:0009086=GO_REF:0000019, GO:0047150=Reactome:REACT_115861, GO:0044281=Reactome:REACT_111217, GO:0032403=GO_REF:0000019, GO:0050666=PMID:10075673, GO:0005829=Reactome:REACT_115861, GO:0043234=GO_REF:0000019, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000052, GO:0000096=Reactome:REACT_115639, GO:0006479=PMID:10075673, GO:0008270=GO_REF:0000002, GO:0006579=GO_REF:0000041, GO:0008898=GO_REF:0000002} Q93088 Betaine--homocysteine S-methyltransferase 1 protein 20110516 {GO:0009086=IEA, GO:0047150=TAS, GO:0044281=TAS, GO:0032403=IEA, GO:0050666=NAS, GO:0005829=TAS, GO:0043234=IEA, GO:0034641=TAS, GO:0005737=IDA, GO:0000096=TAS, GO:0006479=NAS, GO:0008270=IEA, GO:0006579=IEA, GO:0008898=IEA} amino-acid betaine catabolic process, cellular nitrogen compound metabolic process, methionine biosynthetic process, protein methylation, regulation of homocysteine metabolic process, small molecule metabolic process, sulfur amino acid metabolic process cytoplasm, cytosol, protein complex betaine-homocysteine S-methyltransferase activity, homocysteine S-methyltransferase activity, protein complex binding, zinc ion binding Human BHMT2 UniPathway UniProtKB {GO:0005737=GO_REF:0000002, GO:0009086=GO_REF:0000002, GO:0047150=GO_REF:0000003, GO:0008270=GO_REF:0000002, GO:0006579=GO_REF:0000041, GO:0008898=GO_REF:0000002} Q9H2M3 S-methylmethionine--homocysteine S-methyltransferase BHMT2 protein 20130413 {GO:0005737=IEA, GO:0009086=IEA, GO:0047150=IEA, GO:0008270=IEA, GO:0006579=IEA, GO:0008898=IEA} amino-acid betaine catabolic process, methionine biosynthetic process cytoplasm betaine-homocysteine S-methyltransferase activity, homocysteine S-methyltransferase activity, zinc ion binding Human UniPathway:UPA00291 BICD1 BHF-UCL UniProtKB {GO:0005515=PMID:20089649, GO:0005802=PMID:20089649, GO:0005881=PMID:20089649, GO:0048471=PMID:20089649, GO:0034452=PMID:12447383, GO:0031871=PMID:20164183, GO:1900737=GO_REF:0000024, GO:0005634=GO_REF:0000002, GO:0072385=PMID:12447383, GO:0009653=PMID:9367685, GO:0005829=PMID:12447383, GO:0006810=GO_REF:0000002, GO:0016032=PMID:20089649, GO:0005856=PMID:9367685, GO:0072517=PMID:20089649, GO:0008093=PMID:12447383, GO:0045298=PMID:20164183, GO:0006396=PMID:9367685, GO:0017137=PMID:12447383, GO:0006355=GO_REF:0000002, GO:0008298=PMID:9367685, GO:0005794=GO_REF:0000039, GO:0033365=PMID:20089649, GO:0031410=PMID:20089649, GO:0003677=GO_REF:0000002, GO:1900275=GO_REF:0000024, GO:0072393=PMID:19825938, GO:1900276=GO_REF:0000024, GO:0034063=GO_REF:0000024, GO:0045502=PMID:12447383, GO:0016020=PMID:12447383, GO:0019048=GO_REF:0000037, GO:0048260=PMID:20164183, GO:0005200=PMID:9367685} Q96G01 Protein bicaudal D homolog 1 protein 20120404 {GO:0005515=IPI, GO:0005802=IDA, GO:0005881=IDA, GO:0048471=IDA, GO:0034452=IDA, GO:0031871=ISS, GO:1900737=ISS, GO:0005634=IEA, GO:0072385=IMP, GO:0009653=TAS, GO:0005829=IDA, GO:0006810=IEA, GO:0016032=IMP, GO:0005856=NAS, GO:0072517=IDA, GO:0008093=IDA, GO:0045298=TAS, GO:0006396=TAS, GO:0017137=IPI, GO:0006355=IEA, GO:0008298=NAS, GO:0005794=IEA, GO:0033365=IDA, GO:0031410=IDA, GO:0003677=IEA, GO:1900275=ISS, GO:0072393=ISS, GO:1900276=ISS, GO:0034063=ISS, GO:0045502=IDA, GO:0016020=IDA, GO:0019048=IEA, GO:0048260=IMP, GO:0005200=TAS} RNA processing, anatomical structure morphogenesis, intracellular mRNA localization, microtubule anchoring at microtubule organizing center, minus-end-directed organelle transport along microtubule, negative regulation of phospholipase C activity, negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway, positive regulation of receptor-mediated endocytosis, protein localization to organelle, regulation of proteinase activated receptor activity, regulation of transcription, DNA-dependent, stress granule assembly, transport, viral reproduction, virus-host interaction Golgi apparatus, cytoplasmic microtubule, cytoplasmic vesicle, cytoskeleton, cytosol, host cell viral assembly compartment, membrane, nucleus, perinuclear region of cytoplasm, trans-Golgi network, tubulin complex DNA binding, Rab GTPase binding, cytoskeletal adaptor activity, dynactin binding, dynein binding, protein binding, proteinase activated receptor binding, structural constituent of cytoskeleton Human UniProtKB:Q8BR07 BICD2 HPA UniProtKB {GO:0005515=PMID:16417406, GO:0005737=GO_REF:0000052, GO:0017137=GO_REF:0000024, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0031410=GO_REF:0000024, GO:0072385=GO_REF:0000024, GO:0005856=GO_REF:0000039, GO:0072393=GO_REF:0000024} Q8TD16 Protein bicaudal D homolog 2 protein 20101115 {GO:0005515=IPI, GO:0005737=IDA, GO:0017137=ISS, GO:0005794=IDA, GO:0005886=IDA, GO:0031410=ISS, GO:0072385=ISS, GO:0005856=IEA, GO:0072393=ISS} microtubule anchoring at microtubule organizing center, minus-end-directed organelle transport along microtubule Golgi apparatus, cytoplasm, cytoplasmic vesicle, cytoskeleton, plasma membrane Rab GTPase binding, protein binding Human BID BHF-UCL UniProtKB {GO:0005515=PMID:21036904, GO:0008625=PMID:9727491, GO:2001238=PMID:21459798, GO:0006626=GO_REF:0000019, GO:0001836=PMID:17052454, GO:0005741=Reactome:REACT_21389, GO:0051402=PMID:16167175, GO:2000045=GO_REF:0000019, GO:0005829=Reactome:REACT_6160, GO:0005739=PMID:9727491, GO:0008637=PMID:9727492, GO:1900740=Reactome:REACT_701, GO:0042127=GO_REF:0000019, GO:0090200=PMID:21041309, GO:0051260=GO_REF:0000019, GO:0032355=GO_REF:0000019, GO:0031625=GO_REF:0000019, GO:0032464=PMID:21041309, GO:0034349=GO_REF:0000019, GO:0046902=GO_REF:0000019, GO:0043065=PMID:21525171, GO:0090150=PMID:21041309, GO:1901030=Reactome:REACT_707, GO:0006915=Reactome:REACT_578, GO:2001244=Reactome:REACT_330, GO:0005123=PMID:8918887, GO:0097193=Reactome:REACT_964, GO:0016020=PMID:8918887, GO:0032592=GO_REF:0000019, GO:0007420=GO_REF:0000019} P55957 BH3-interacting domain death agonist protein 20110317 {GO:0005515=IPI, GO:0008625=TAS, GO:2001238=IMP, GO:0006626=IEA, GO:0001836=IDA, GO:0005741=TAS, GO:0051402=TAS, GO:2000045=IEA, GO:0005829=TAS, GO:0005739=TAS, GO:0008637=TAS, GO:1900740=TAS, GO:0042127=IEA, GO:0090200=IGI, GO:0051260=IEA, GO:0032355=IEA, GO:0031625=IEA, GO:0032464=IDA, GO:0034349=IEA, GO:0046902=IEA, GO:0043065=IMP, GO:0090150=IDA, GO:1901030=TAS, GO:0006915=TAS, GO:2001244=TAS, GO:0005123=TAS, GO:0097193=TAS, GO:0016020=TAS, GO:0032592=IEA, GO:0007420=IEA} apoptotic mitochondrial changes, apoptotic process, brain development, establishment of protein localization to membrane, extrinsic apoptotic signaling pathway via death domain receptors, glial cell apoptotic process, intrinsic apoptotic signaling pathway, neuron apoptotic process, positive regulation of apoptotic process, positive regulation of extrinsic apoptotic signaling pathway, positive regulation of intrinsic apoptotic signaling pathway, positive regulation of mitochondrial outer membrane permeabilization, positive regulation of protein homooligomerization, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, positive regulation of release of cytochrome c from mitochondria, protein homooligomerization, protein targeting to mitochondrion, regulation of G1/S transition of mitotic cell cycle, regulation of cell proliferation, regulation of mitochondrial membrane permeability, release of cytochrome c from mitochondria, response to estradiol stimulus cytosol, integral to mitochondrial membrane, membrane, mitochondrial outer membrane, mitochondrion death receptor binding, protein binding, ubiquitin protein ligase binding Human BIK BHF-UCL UniProtKB {GO:0032464=PMID:21041309, GO:0005515=PMID:17289999, GO:0051400=GO_REF:0000019, GO:0031966=GO_REF:0000039, GO:0046982=GO_REF:0000019, GO:0090200=PMID:21041309, GO:0006915=GO_REF:0000037, GO:0006917=PMID:10381623, GO:0007283=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0008584=GO_REF:0000019, GO:0012505=GO_REF:0000039} Q13323 Bcl-2-interacting killer protein 20110317 {GO:0032464=IDA, GO:0005515=IPI, GO:0051400=IEA, GO:0031966=IEA, GO:0046982=IEA, GO:0090200=IDA, GO:0006915=IEA, GO:0006917=TAS, GO:0007283=IEA, GO:0016021=IEA, GO:0008584=IEA, GO:0012505=IEA} apoptotic process, induction of apoptosis, male gonad development, positive regulation of protein homooligomerization, positive regulation of release of cytochrome c from mitochondria, spermatogenesis endomembrane system, integral to membrane, mitochondrial membrane BH domain binding, protein binding, protein heterodimerization activity Human BIN1 HPA UniProtKB {GO:0005515=PMID:16275660, GO:0046982=GO_REF:0000019, GO:0008283=PMID:8782822, GO:0044300=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0015629=PMID:9182667, GO:0032403=GO_REF:0000019, GO:0006897=GO_REF:0000037, GO:0008021=GO_REF:0000019, GO:0042692=GO_REF:0000019, GO:0043547=GO_REF:0000019, GO:0045807=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0051020=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0043196=GO_REF:0000019, GO:0043679=GO_REF:0000019} O00499 Myc box-dependent-interacting protein 1 protein 20080205 {GO:0005515=IPI, GO:0046982=IEA, GO:0008283=TAS, GO:0044300=IEA, GO:0005634=IEA, GO:0007275=IEA, GO:0015629=TAS, GO:0032403=IEA, GO:0006897=IEA, GO:0008021=IEA, GO:0042692=IEA, GO:0043547=IEA, GO:0045807=IEA, GO:0005737=IDA, GO:0051020=IEA, GO:0019048=IEA, GO:0043196=IEA, GO:0043679=IEA} cell proliferation, endocytosis, multicellular organismal development, muscle cell differentiation, positive regulation of GTPase activity, positive regulation of endocytosis, virus-host interaction actin cytoskeleton, axon terminus, cerebellar mossy fiber, cytoplasm, nucleus, synaptic vesicle, varicosity GTPase binding, protein binding, protein complex binding, protein heterodimerization activity Human BIN2 IntAct UniProtKB {GO:0005515=PMID:10903846, GO:0071800=PMID:23285027, GO:0005737=GO_REF:0000002, GO:0005543=PMID:23285027, GO:0030054=GO_REF:0000037, GO:0060326=PMID:23285027, GO:0097320=PMID:23285027, GO:0002102=PMID:23285027, GO:0001891=PMID:23285027, GO:0042995=GO_REF:0000037, GO:0006911=PMID:23285027, GO:0005938=GO_REF:0000039} Q9UBW5 Bridging integrator 2 protein 20130415 {GO:0005515=IPI, GO:0071800=IMP, GO:0005737=IEA, GO:0005543=IDA, GO:0030054=IEA, GO:0060326=IMP, GO:0097320=IDA, GO:0002102=IDA, GO:0001891=IDA, GO:0042995=IEA, GO:0006911=IMP, GO:0005938=IEA} cell chemotaxis, membrane tubulation, phagocytosis, engulfment, podosome assembly cell cortex, cell junction, cell projection, cytoplasm, phagocytic cup, podosome phospholipid binding, protein binding Human UniProtKB:O00499 BIN3 IntAct UniProtKB {GO:0005515=PMID:18654987, GO:0000910=PMID:11274158, GO:0007049=GO_REF:0000037, GO:0005737=GO_REF:0000037, GO:0008104=PMID:11274158, GO:0007015=PMID:11274158, GO:0000917=GO_REF:0000037, GO:0005856=GO_REF:0000039, GO:0009826=PMID:11274158, GO:0008093=PMID:11274158} Q9NQY0 Bridging integrator 3 protein 20130415 {GO:0005515=IPI, GO:0000910=NAS, GO:0007049=IEA, GO:0005737=IEA, GO:0008104=IMP, GO:0007015=NAS, GO:0000917=IEA, GO:0005856=IEA, GO:0009826=IMP, GO:0008093=NAS} actin filament organization, barrier septum assembly, cell cycle, cytokinesis, protein localization, unidimensional cell growth cytoplasm, cytoskeleton cytoskeletal adaptor activity, protein binding Human UniProtKB:Q6XZF7 BIRC2 BHF-UCL UniProtKB {GO:0005515=PMID:21988832, GO:0035631=GO_REF:0000024, GO:0004842=PMID:11907583, GO:0034142=Reactome:REACT_6894, GO:0034121=PMID:20888210, GO:0070424=PMID:20888210, GO:0005634=PMID:15665297, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_12045, GO:0005622=GO_REF:0000002, GO:0002756=Reactome:REACT_6809, GO:0042127=PMID:18414036, GO:0051726=PMID:15665297, GO:0043123=PMID:12761501, GO:0034138=Reactome:REACT_6783, GO:0000209=PMID:11907583, GO:0006355=GO_REF:0000037, GO:0043066=PMID:21525013, GO:0070266=GO_REF:0000019, GO:0003713=PMID:21653699, GO:0050727=PMID:21447281, GO:0006915=Reactome:REACT_578, GO:0042981=GO_REF:0000019, GO:2000116=PMID:20651737, GO:0001890=GO_REF:0000019, GO:0039535=PMID:20888210, GO:0002224=Reactome:REACT_6966, GO:0006351=GO_REF:0000037, GO:0038061=PMID:20651737, GO:0047485=PMID:19153467, GO:0045087=Reactome:REACT_6802, GO:0045088=PMID:21447281, GO:0009898=GO_REF:0000024, GO:0035666=Reactome:REACT_25281, GO:0043161=PMID:11907583, GO:0008270=PMID:19153467, GO:0045595=PMID:18414036, GO:0007166=PMID:8548810} Q13490 Baculoviral IAP repeat-containing protein 2 protein 20110110 {GO:0005515=IPI, GO:0035631=ISS, GO:0004842=IDA, GO:0034142=TAS, GO:0034121=TAS, GO:0070424=TAS, GO:0005634=IDA, GO:0006921=TAS, GO:0005829=TAS, GO:0005622=IEA, GO:0002756=TAS, GO:0042127=TAS, GO:0051726=IDA, GO:0043123=IEP, GO:0034138=TAS, GO:0000209=IDA, GO:0006355=IEA, GO:0043066=IDA, GO:0070266=IEA, GO:0003713=IMP, GO:0050727=TAS, GO:0006915=TAS, GO:0042981=IEA, GO:2000116=TAS, GO:0001890=IEA, GO:0039535=TAS, GO:0002224=TAS, GO:0006351=IEA, GO:0038061=TAS, GO:0047485=IPI, GO:0045087=TAS, GO:0045088=TAS, GO:0009898=ISS, GO:0035666=TAS, GO:0043161=IDA, GO:0008270=IDA, GO:0045595=TAS, GO:0007166=TAS} MyD88-independent toll-like receptor signaling pathway, NIK/NF-kappaB cascade, TRIF-dependent toll-like receptor signaling pathway, apoptotic process, cell surface receptor signaling pathway, cellular component disassembly involved in execution phase of apoptosis, innate immune response, necroptosis, negative regulation of apoptotic process, placenta development, positive regulation of I-kappaB kinase/NF-kappaB cascade, proteasomal ubiquitin-dependent protein catabolic process, protein polyubiquitination, regulation of RIG-I signaling pathway, regulation of apoptotic process, regulation of cell cycle, regulation of cell differentiation, regulation of cell proliferation, regulation of cysteine-type endopeptidase activity, regulation of inflammatory response, regulation of innate immune response, regulation of nucleotide-binding oligomerization domain containing signaling pathway, regulation of toll-like receptor signaling pathway, regulation of transcription, DNA-dependent, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor signaling pathway, transcription, DNA-dependent CD40 receptor complex, cytosol, internal side of plasma membrane, intracellular, nucleus protein N-terminus binding, protein binding, transcription coactivator activity, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q62210 BIRC3 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0004842=PMID:16395405, GO:0034142=Reactome:REACT_6894, GO:0034121=PMID:20888210, GO:0070424=PMID:20888210, GO:0005634=PMID:15665297, GO:0005829=Reactome:REACT_6884, GO:0005622=GO_REF:0000002, GO:0002756=Reactome:REACT_6809, GO:0005737=PMID:15665297, GO:0043123=PMID:20651737, GO:0034138=Reactome:REACT_6783, GO:0060546=GO_REF:0000019, GO:0043066=PMID:8552191, GO:0070266=GO_REF:0000019, GO:0050727=PMID:21447281, GO:0006915=GO_REF:0000037, GO:0042981=GO_REF:0000002, GO:2000116=PMID:20651737, GO:0039535=PMID:20888210, GO:0002224=Reactome:REACT_6966, GO:0038061=PMID:20651737, GO:0042326=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0045088=PMID:21447281, GO:0035666=Reactome:REACT_25281, GO:0008270=GO_REF:0000002, GO:2000378=GO_REF:0000019, GO:0007166=PMID:8548810} Q13489 Baculoviral IAP repeat-containing protein 3 protein 20130415 {GO:0005515=IPI, GO:0004842=IDA, GO:0034142=TAS, GO:0034121=TAS, GO:0070424=TAS, GO:0005634=IDA, GO:0005829=TAS, GO:0005622=IEA, GO:0002756=TAS, GO:0005737=IDA, GO:0043123=TAS, GO:0034138=TAS, GO:0060546=IEA, GO:0043066=TAS, GO:0070266=IEA, GO:0050727=TAS, GO:0006915=IEA, GO:0042981=IEA, GO:2000116=TAS, GO:0039535=TAS, GO:0002224=TAS, GO:0038061=TAS, GO:0042326=IEA, GO:0045087=TAS, GO:0045088=TAS, GO:0035666=TAS, GO:0008270=IEA, GO:2000378=IEA, GO:0007166=TAS} MyD88-independent toll-like receptor signaling pathway, NIK/NF-kappaB cascade, TRIF-dependent toll-like receptor signaling pathway, apoptotic process, cell surface receptor signaling pathway, innate immune response, necroptosis, negative regulation of apoptotic process, negative regulation of necroptosis, negative regulation of phosphorylation, negative regulation of reactive oxygen species metabolic process, positive regulation of I-kappaB kinase/NF-kappaB cascade, regulation of RIG-I signaling pathway, regulation of apoptotic process, regulation of cysteine-type endopeptidase activity, regulation of inflammatory response, regulation of innate immune response, regulation of nucleotide-binding oligomerization domain containing signaling pathway, regulation of toll-like receptor signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor signaling pathway cytoplasm, cytosol, intracellular, nucleus protein binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q12933 BIRC5 LIFEdb UniProtKB {GO:0008017=PMID:21536684, GO:0005515=PMID:18243099, GO:0000236=Reactome:REACT_682, GO:0008284=PMID:16344111, GO:0004869=GO_REF:0000037, GO:0031503=PMID:16239925, GO:0051087=PMID:18086682, GO:0005634=PMID:20826784, GO:0009790=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_150414, GO:0005737=GO_REF:0000054, GO:0043524=GO_REF:0000019, GO:0007059=GO_REF:0000037, GO:0000087=Reactome:REACT_910, GO:0008536=PMID:18591255, GO:0005874=GO_REF:0000037, GO:0005819=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0000226=GO_REF:0000019, GO:0030496=PMID:11084331, GO:0042981=PMID:21536684, GO:0000228=PMID:16322459, GO:0006351=GO_REF:0000037, GO:0032133=PMID:18591255, GO:0000777=PMID:15665297, GO:0006468=PMID:21252625, GO:0000278=Reactome:REACT_152, GO:0019899=PMID:16322459, GO:0000090=Reactome:REACT_1275, GO:0045892=PMID:20826784, GO:0000775=PMID:11084331, GO:0051301=GO_REF:0000037} O15392 Baculoviral IAP repeat-containing protein 5 protein 20100607 {GO:0008017=TAS, GO:0005515=IPI, GO:0000236=TAS, GO:0008284=TAS, GO:0004869=IEA, GO:0031503=IMP, GO:0051087=IPI, GO:0005634=IDA, GO:0009790=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0043524=IEA, GO:0007059=IEA, GO:0000087=TAS, GO:0008536=IPI, GO:0005874=IEA, GO:0005819=IEA, GO:0006915=IEA, GO:0000226=IEA, GO:0030496=IDA, GO:0042981=IMP, GO:0000228=IDA, GO:0006351=IEA, GO:0032133=IPI, GO:0000777=IDA, GO:0006468=IDA, GO:0000278=TAS, GO:0019899=IPI, GO:0000090=TAS, GO:0045892=IMP, GO:0000775=IDA, GO:0051301=IEA} M phase of mitotic cell cycle, apoptotic process, cell division, chromosome segregation, embryo development, microtubule cytoskeleton organization, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, negative regulation of neuron apoptotic process, negative regulation of transcription, DNA-dependent, positive regulation of cell proliferation, protein complex localization, protein phosphorylation, regulation of apoptotic process, transcription, DNA-dependent chromosome passenger complex, chromosome, centromeric region, condensed chromosome kinetochore, cytoplasm, cytosol, microtubule, midbody, nuclear chromosome, nucleus, spindle Ran GTPase binding, chaperone binding, cysteine-type endopeptidase inhibitor activity, enzyme binding, metal ion binding, microtubule binding, protein binding Human BIRC6 IntAct UniProtKB {GO:0005802=PMID:18329369, GO:0005515=PMID:18329369, GO:0008284=GO_REF:0000019, GO:0060711=GO_REF:0000019, GO:0043066=PMID:15200957, GO:0004842=PMID:15200957, GO:0016567=PMID:18329369, GO:0032465=PMID:18329369, GO:0004869=PMID:15200957, GO:0005794=GO_REF:0000039, GO:0005815=PMID:18329369, GO:0060712=GO_REF:0000019, GO:0030496=PMID:18329369, GO:0006915=GO_REF:0000037, GO:0005575=GO_REF:0000015, GO:0000922=PMID:18329369, GO:0007067=GO_REF:0000037, GO:0016020=GO_REF:0000019, GO:0042127=PMID:18414036, GO:0006468=PMID:18329369, GO:0005768=PMID:18329369, GO:0051301=GO_REF:0000037} Q9NR09 Baculoviral IAP repeat-containing protein 6 protein 20130415 {GO:0005802=IDA, GO:0005515=IPI, GO:0008284=IEA, GO:0060711=IEA, GO:0043066=IMP, GO:0004842=IDA, GO:0016567=TAS, GO:0032465=IMP, GO:0004869=IMP, GO:0005794=IEA, GO:0005815=IDA, GO:0060712=IEA, GO:0030496=IDA, GO:0006915=IEA, GO:0005575=ND, GO:0000922=IDA, GO:0007067=IEA, GO:0016020=IEA, GO:0042127=TAS, GO:0006468=TAS, GO:0005768=IDA, GO:0051301=IEA} apoptotic process, cell division, labyrinthine layer development, mitosis, negative regulation of apoptotic process, positive regulation of cell proliferation, protein phosphorylation, protein ubiquitination, regulation of cell proliferation, regulation of cytokinesis, spongiotrophoblast layer development Golgi apparatus, cellular_component, endosome, membrane, microtubule organizing center, midbody, spindle pole, trans-Golgi network cysteine-type endopeptidase inhibitor activity, protein binding, ubiquitin-protein ligase activity Human UniProtKB:Q02750 BIRC7 IntAct UniProtKB {GO:0005515=PMID:11801603, GO:0043066=PMID:16729033, GO:0004842=PMID:16729033, GO:0016567=PMID:16729033, GO:0005794=PMID:17294084, GO:0004869=PMID:21617971, GO:0005634=PMID:17294084, GO:0070247=PMID:18034418, GO:0007257=PMID:11865055, GO:0005737=PMID:17294084, GO:0006309=PMID:11024045, GO:0042127=PMID:21617971, GO:0008270=GO_REF:0000002, GO:0019899=PMID:11801603} Q96CA5 Baculoviral IAP repeat-containing protein 7 protein 20130415 {GO:0005515=IPI, GO:0043066=IMP, GO:0004842=IDA, GO:0016567=IDA, GO:0005794=IDA, GO:0004869=TAS, GO:0005634=IDA, GO:0070247=IDA, GO:0007257=NAS, GO:0005737=IDA, GO:0006309=NAS, GO:0042127=IDA, GO:0008270=IEA, GO:0019899=NAS} activation of JUN kinase activity, apoptotic DNA fragmentation, negative regulation of apoptotic process, protein ubiquitination, regulation of cell proliferation, regulation of natural killer cell apoptotic process Golgi apparatus, cytoplasm, nucleus cysteine-type endopeptidase inhibitor activity, enzyme binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q9NR28 BIRC8 ENSEMBL UniProtKB {GO:0043234=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0043524=GO_REF:0000019, GO:0097110=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0043154=GO_REF:0000019, GO:0002020=GO_REF:0000019, GO:0005829=GO_REF:0000019} Q96P09 Baculoviral IAP repeat-containing protein 8 protein 20130413 {GO:0043234=IEA, GO:0048471=IEA, GO:0043524=IEA, GO:0097110=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0043154=IEA, GO:0002020=IEA, GO:0005829=IEA} negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of neuron apoptotic process cytosol, nucleus, perinuclear region of cytoplasm, protein complex protease binding, scaffold protein binding, zinc ion binding Human Ensembl:ENSRNOP00000009336 BIVM UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039} Q86UB2 Basic immunoglobulin-like variable motif-containing protein protein 20130413 {GO:0005737=IEA, GO:0005634=IEA} cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 BLCAP IntAct UniProtKB {GO:0005515=PMID:21217774, GO:0007049=GO_REF:0000037, GO:0006915=PMID:17031575, GO:0016021=GO_REF:0000037} P62952 Bladder cancer-associated protein protein 20130415 {GO:0005515=IPI, GO:0007049=IEA, GO:0006915=IDA, GO:0016021=IEA} apoptotic process, cell cycle integral to membrane protein binding Human UniProtKB:P03372 BLID UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0006915=GO_REF:0000037} Q8IZY5 BH3-like motif-containing cell death inducer protein 20130413 {GO:0005739=IEA, GO:0006915=IEA} apoptotic process mitochondrion Human UniProtKB-SubCell:SL-0173 BLK PINC UniProtKB {GO:0050853=PMID:876631, GO:0004672=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0032024=PMID:19667185, GO:0004713=PMID:7845672, GO:0004715=PMID:876631, GO:0005524=GO_REF:0000037, GO:0007243=PMID:2404338} P51451 Tyrosine-protein kinase Blk protein 20030904 {GO:0050853=IDA, GO:0004672=IEA, GO:0005886=IEA, GO:0032024=IMP, GO:0004713=TAS, GO:0004715=IDA, GO:0005524=IEA, GO:0007243=TAS} B cell receptor signaling pathway, intracellular protein kinase cascade, positive regulation of insulin secretion plasma membrane ATP binding, non-membrane spanning protein tyrosine kinase activity, protein kinase activity, protein tyrosine kinase activity Human BLM GOC UniProtKB {GO:0005515=PMID:16030011, GO:0006200=PMID:17878217, GO:0010165=PMID:11309417, GO:0048478=PMID:10779560, GO:0005657=GO_REF:0000019, GO:0046632=GO_REF:0000019, GO:0031572=PMID:11309417, GO:0005634=GO_REF:0000052, GO:0000079=PMID:15604258, GO:0051259=PMID:10359700, GO:0016363=PMID:11309417, GO:0000085=PMID:11309417, GO:0002039=PMID:11781842, GO:0005737=GO_REF:0000052, GO:0004003=PMID:21325134, GO:0000723=GO_REF:0000019, GO:0003697=PMID:12818200, GO:0000724=PMID:11309417, GO:0046641=GO_REF:0000019, GO:0051782=PMID:11781842, GO:0016887=PMID:17878217, GO:0000729=PMID:21325134, GO:0008026=PMID:12818200, GO:0000781=PMID:10779560, GO:0043140=GO_REF:0000019, GO:0000405=PMID:11433031, GO:0005730=PMID:10779560, GO:0004386=PMID:17878217, GO:0051880=PMID:11433031, GO:0006310=PMID:7585968, GO:0051098=GO_REF:0000019, GO:0000800=PMID:10728666, GO:0005524=PMID:17878217, GO:0003677=GO_REF:0000002, GO:0006974=PMID:12818200, GO:0006260=GO_REF:0000002, GO:0000733=PMID:17878217, GO:0036310=PMID:17878217, GO:0045950=GO_REF:0000019, GO:0006281=PMID:7585968, GO:0009378=PMID:11433031, GO:0016605=PMID:10728666, GO:0031297=PMID:17115688, GO:0045120=GO_REF:0000019, GO:0045893=PMID:11781842, GO:0001673=GO_REF:0000019, GO:0045910=PMID:9671747} P54132 Bloom syndrome protein protein 20130413 {GO:0005515=IPI, GO:0006200=IDA, GO:0010165=IDA, GO:0048478=NAS, GO:0005657=IEA, GO:0046632=IEA, GO:0031572=NAS, GO:0005634=IDA, GO:0000079=IMP, GO:0051259=IDA, GO:0016363=IDA, GO:0000085=NAS, GO:0002039=IPI, GO:0005737=IDA, GO:0004003=IMP, GO:0000723=IEA, GO:0003697=IDA, GO:0000724=NAS, GO:0046641=IEA, GO:0051782=IMP, GO:0016887=IDA, GO:0000729=IDA, GO:0008026=IDA, GO:0000781=IDA, GO:0043140=IEA, GO:0000405=IDA, GO:0005730=IDA, GO:0004386=IDA, GO:0051880=IDA, GO:0006310=NAS, GO:0051098=IEA, GO:0000800=IDA, GO:0005524=IDA, GO:0003677=IEA, GO:0006974=IMP, GO:0006260=IEA, GO:0000733=IDA, GO:0036310=IDA, GO:0045950=IEA, GO:0006281=NAS, GO:0009378=IDA, GO:0016605=IDA, GO:0031297=IDA, GO:0045120=IEA, GO:0045893=IDA, GO:0001673=IEA, GO:0045910=IMP} ATP catabolic process, DNA double-strand break processing, DNA recombination, DNA repair, DNA replication, DNA strand renaturation, G2 DNA damage checkpoint, G2 phase of mitotic cell cycle, alpha-beta T cell differentiation, double-strand break repair via homologous recombination, negative regulation of DNA recombination, negative regulation of cell division, negative regulation of mitotic recombination, positive regulation of alpha-beta T cell proliferation, positive regulation of transcription, DNA-dependent, protein oligomerization, regulation of binding, regulation of cyclin-dependent protein serine/threonine kinase activity, replication fork processing, replication fork protection, response to DNA damage stimulus, response to X-ray, telomere maintenance PML body, chromosome, telomeric region, cytoplasm, lateral element, male germ cell nucleus, nuclear matrix, nucleolus, nucleus, pronucleus, replication fork ATP binding, ATP-dependent 3'-5' DNA helicase activity, ATP-dependent DNA helicase activity, ATP-dependent helicase activity, ATPase activity, DNA binding, G-quadruplex DNA binding, annealing helicase activity, bubble DNA binding, four-way junction helicase activity, helicase activity, p53 binding, protein binding, single-stranded DNA binding Human BLMH HPA UniProtKB {GO:0000209=Reactome:REACT_75842, GO:0005515=PMID:11350084, GO:0002474=Reactome:REACT_75820, GO:0042493=GO_REF:0000019, GO:0009636=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0005829=Reactome:REACT_75931, GO:0004197=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0004177=PMID:9546396, GO:0006508=GO_REF:0000037, GO:0004180=PMID:9546396, GO:0008234=PMID:8639621} Q13867 Bleomycin hydrolase protein 20110516 {GO:0000209=TAS, GO:0005515=IPI, GO:0002474=TAS, GO:0042493=IEA, GO:0009636=IEA, GO:0005634=IDA, GO:0005829=TAS, GO:0004197=IEA, GO:0005737=IDA, GO:0004177=TAS, GO:0006508=IEA, GO:0004180=TAS, GO:0008234=TAS} antigen processing and presentation of peptide antigen via MHC class I, protein polyubiquitination, proteolysis, response to drug, response to toxic substance cytoplasm, cytosol, nucleus aminopeptidase activity, carboxypeptidase activity, cysteine-type endopeptidase activity, cysteine-type peptidase activity, protein binding Human BLNK GOC UniProtKB {GO:0005515=PMID:21930792, GO:0005622=PMID:9341187, GO:0035556=PMID:9341187, GO:0006954=PMID:9697839, GO:0005886=Reactome:REACT_118834, GO:0006959=PMID:9697839, GO:0005070=PMID:19641626, GO:0030183=PMID:10583958, GO:0005068=PMID:9697839, GO:0007169=PMID:9697839, GO:0005829=Reactome:REACT_118834} Q8WV28 B-cell linker protein protein 20130413 {GO:0005515=IPI, GO:0005622=NAS, GO:0035556=IDA, GO:0006954=TAS, GO:0005886=TAS, GO:0006959=TAS, GO:0005070=RCA, GO:0030183=NAS, GO:0005068=TAS, GO:0007169=TAS, GO:0005829=TAS} B cell differentiation, humoral immune response, inflammatory response, intracellular signal transduction, transmembrane receptor protein tyrosine kinase signaling pathway cytosol, intracellular, plasma membrane SH3/SH2 adaptor activity, protein binding, transmembrane receptor protein tyrosine kinase adaptor activity Human BLOC1S1 IntAct UniProtKB {GO:0005515=PMID:22309213, GO:0048490=GO_REF:0000024, GO:0032438=PMID:22203680, GO:0006892=Reactome:REACT_11235, GO:0005765=Reactome:REACT_19390, GO:0018394=PMID:22309213, GO:0031175=GO_REF:0000024, GO:0005829=PMID:22309213, GO:0009060=PMID:22309213, GO:0005758=PMID:22309213, GO:0031083=PMID:22203680, GO:0005759=PMID:22309213, GO:0060155=PMID:15102850, GO:0008089=GO_REF:0000024, GO:0016044=Reactome:REACT_11123} P78537 Biogenesis of lysosome-related organelles complex 1 subunit 1 protein 20130415 {GO:0005515=IPI, GO:0048490=ISS, GO:0032438=NAS, GO:0006892=TAS, GO:0005765=TAS, GO:0018394=IMP, GO:0031175=ISS, GO:0005829=IDA, GO:0009060=IMP, GO:0005758=IDA, GO:0031083=IDA, GO:0005759=IDA, GO:0060155=NAS, GO:0008089=ISS, GO:0016044=TAS} aerobic respiration, anterograde axon cargo transport, anterograde synaptic vesicle transport, cellular membrane organization, melanosome organization, neuron projection development, peptidyl-lysine acetylation, platelet dense granule organization, post-Golgi vesicle-mediated transport BLOC-1 complex, cytosol, lysosomal membrane, mitochondrial intermembrane space, mitochondrial matrix protein binding Human UniProtKB:Q16795 BLOC1S2 IntAct UniProtKB {GO:0005515=PMID:18188704, GO:0005813=GO_REF:0000019, GO:0048490=GO_REF:0000024, GO:0043015=PMID:15381421, GO:0032438=PMID:22203680, GO:0005634=GO_REF:0000019, GO:0042981=PMID:18188704, GO:0008022=GO_REF:0000019, GO:0031175=GO_REF:0000024, GO:0031083=PMID:22203680, GO:0045944=GO_REF:0000033, GO:0000930=PMID:15381421, GO:0060155=PMID:15102850, GO:0008089=GO_REF:0000024, GO:0055037=GO_REF:0000019} Q6QNY1 Biogenesis of lysosome-related organelles complex 1 subunit 2 protein 20130415 {GO:0005515=IPI, GO:0005813=IEA, GO:0048490=ISS, GO:0043015=IDA, GO:0032438=NAS, GO:0005634=IEA, GO:0042981=IMP, GO:0008022=IEA, GO:0031175=ISS, GO:0031083=IDA, GO:0045944=IBA, GO:0000930=IDA, GO:0060155=NAS, GO:0008089=ISS, GO:0055037=IEA} anterograde axon cargo transport, anterograde synaptic vesicle transport, melanosome organization, neuron projection development, platelet dense granule organization, positive regulation of transcription from RNA polymerase II promoter, regulation of apoptotic process BLOC-1 complex, centrosome, gamma-tubulin complex, nucleus, recycling endosome gamma-tubulin binding, protein C-terminus binding, protein binding Human UniProtKB:Q9NWB7 BLOC1S3 Reactome UniProtKB {GO:0030133=PMID:17182842, GO:0048490=GO_REF:0000024, GO:0042493=GO_REF:0000019, GO:0032438=PMID:22203680, GO:0001654=PMID:16385460, GO:0006892=Reactome:REACT_11235, GO:0030168=PMID:16385460, GO:0032402=PMID:17182842, GO:0031175=GO_REF:0000024, GO:0005829=Reactome:REACT_19390, GO:0032816=GO_REF:0000019, GO:0003674=GO_REF:0000015, GO:0031083=PMID:22203680, GO:0033299=GO_REF:0000019, GO:0035646=PMID:17182842, GO:0043473=PMID:16385460, GO:0060155=PMID:15102850, GO:0008089=GO_REF:0000024, GO:0016044=Reactome:REACT_11123} Q6QNY0 Biogenesis of lysosome-related organelles complex 1 subunit 3 protein 20090721 {GO:0030133=IDA, GO:0048490=ISS, GO:0042493=IEA, GO:0032438=NAS, GO:0001654=IMP, GO:0006892=TAS, GO:0030168=IMP, GO:0032402=IDA, GO:0031175=ISS, GO:0005829=TAS, GO:0032816=IEA, GO:0003674=ND, GO:0031083=IDA, GO:0033299=IEA, GO:0035646=IDA, GO:0043473=IMP, GO:0060155=NAS, GO:0008089=ISS, GO:0016044=TAS} anterograde axon cargo transport, anterograde synaptic vesicle transport, cellular membrane organization, endosome to melanosome transport, eye development, melanosome organization, melanosome transport, neuron projection development, pigmentation, platelet activation, platelet dense granule organization, positive regulation of natural killer cell activation, post-Golgi vesicle-mediated transport, response to drug, secretion of lysosomal enzymes BLOC-1 complex, cytosol, transport vesicle molecular_function Human BLVRA Reactome UniProtKB {GO:0006778=Reactome:REACT_9431, GO:0004074=PMID:10858451, GO:0016491=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0042167=Reactome:REACT_22297, GO:0005829=Reactome:REACT_22177, GO:0055114=PMID:10858451} P53004 Biliverdin reductase A protein 20061120 {GO:0006778=TAS, GO:0004074=IDA, GO:0016491=IEA, GO:0008270=IEA, GO:0044281=TAS, GO:0042167=TAS, GO:0005829=TAS, GO:0055114=IDA} heme catabolic process, oxidation-reduction process, porphyrin-containing compound metabolic process, small molecule metabolic process cytosol biliverdin reductase activity, oxidoreductase activity, zinc ion binding Human BLVRB HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0006778=Reactome:REACT_9431, GO:0042602=PMID:11224564, GO:0004074=PMID:7929092, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0042167=Reactome:REACT_22297, GO:0005829=Reactome:REACT_22177} P30043 Flavin reductase (NADPH) protein 20120912 {GO:0005737=IDA, GO:0005886=IDA, GO:0006778=TAS, GO:0042602=IDA, GO:0004074=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0042167=TAS, GO:0005829=TAS} heme catabolic process, porphyrin-containing compound metabolic process, small molecule metabolic process cytoplasm, cytosol, nucleolus, nucleus, plasma membrane biliverdin reductase activity, riboflavin reductase (NADPH) activity Human BLZF1 HPA UniProtKB {GO:0003700=PMID:9129147, GO:0006357=PMID:9129147, GO:0008283=PMID:9129147, GO:0043001=PMID:11739401, GO:0005796=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0001558=PMID:9129147, GO:0003677=PMID:9129147, GO:0005737=PMID:11056056, GO:0000088=Reactome:REACT_765, GO:0000139=Reactome:REACT_147850, GO:0000087=Reactome:REACT_910, GO:0007030=PMID:11739401, GO:0000278=Reactome:REACT_152, GO:0019899=PMID:21478859, GO:0031625=PMID:21478859} Q9H2G9 Golgin-45 protein 20100326 {GO:0003700=NAS, GO:0006357=TAS, GO:0008283=TAS, GO:0043001=IDA, GO:0005796=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0001558=NAS, GO:0003677=NAS, GO:0005737=NAS, GO:0000088=TAS, GO:0000139=TAS, GO:0000087=TAS, GO:0007030=IDA, GO:0000278=TAS, GO:0019899=IPI, GO:0031625=IPI} Golgi organization, Golgi to plasma membrane protein transport, M phase of mitotic cell cycle, cell proliferation, mitotic cell cycle, mitotic prophase, regulation of cell growth, regulation of transcription from RNA polymerase II promoter Golgi lumen, Golgi membrane, cytoplasm, nucleolus, nucleus DNA binding, enzyme binding, sequence-specific DNA binding transcription factor activity, ubiquitin protein ligase binding NOT Human BMF BHF-UCL UniProtKB {GO:0005515=PMID:11546872, GO:0032464=GO_REF:0000024, GO:1900740=Reactome:REACT_2100, GO:0005886=Reactome:REACT_1981, GO:0001669=GO_REF:0000019, GO:0090200=GO_REF:0000024, GO:0006915=Reactome:REACT_578, GO:2001244=Reactome:REACT_330, GO:0005741=Reactome:REACT_21389, GO:0016459=PMID:11546872, GO:0097193=Reactome:REACT_964, GO:0005829=Reactome:REACT_1981} Q96LC9 Bcl-2-modifying factor protein 20110317 {GO:0005515=IPI, GO:0032464=ISS, GO:1900740=TAS, GO:0005886=TAS, GO:0001669=IEA, GO:0090200=ISS, GO:0006915=TAS, GO:2001244=TAS, GO:0005741=TAS, GO:0016459=ISS, GO:0097193=TAS, GO:0005829=TAS} apoptotic process, intrinsic apoptotic signaling pathway, positive regulation of intrinsic apoptotic signaling pathway, positive regulation of protein homooligomerization, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, positive regulation of release of cytochrome c from mitochondria acrosomal vesicle, cytosol, mitochondrial outer membrane, myosin complex, plasma membrane protein binding Human UniProtKB:Q91ZE9 BMI1 ENSEMBL UniProtKB {GO:0010468=PMID:17420273, GO:0005515=PMID:22897849, GO:0048103=GO_REF:0000019, GO:0004842=GO_REF:0000019, GO:0030890=GO_REF:0000019, GO:0000151=GO_REF:0000019, GO:0048704=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0048146=PMID:17420273, GO:0005737=GO_REF:0000039, GO:0006959=GO_REF:0000019, GO:0051443=PMID:16714294, GO:0071535=PMID:16714294, GO:0021903=GO_REF:0000019, GO:0031519=GO_REF:0000019, GO:0030097=PMID:15334543, GO:0035102=PMID:19636380, GO:0043066=GO_REF:0000019, GO:0007379=PMID:7715727, GO:0016573=GO_REF:0000019, GO:0016574=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0000122=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0033092=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0016604=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0008270=GO_REF:0000002} Q5T8Z6 Polycomb complex protein BMI-1 protein 20130413 {GO:0010468=IMP, GO:0005515=IPI, GO:0048103=IEA, GO:0004842=IEA, GO:0030890=IEA, GO:0000151=IEA, GO:0048704=IEA, GO:0005634=IDA, GO:0048146=IMP, GO:0005737=IEA, GO:0006959=IEA, GO:0051443=IDA, GO:0071535=IPI, GO:0021903=IEA, GO:0031519=IEA, GO:0030097=IEP, GO:0035102=IDA, GO:0043066=IEA, GO:0007379=TAS, GO:0016573=IEA, GO:0016574=IEA, GO:0005730=IDA, GO:0000122=IEA, GO:0001701=IEA, GO:0006351=IEA, GO:0033092=IEA, GO:0043565=IEA, GO:0016604=IEA, GO:0007420=IEA, GO:0003682=IEA, GO:0008270=IEA} brain development, embryonic skeletal system morphogenesis, hemopoiesis, histone acetylation, histone ubiquitination, humoral immune response, in utero embryonic development, negative regulation of apoptotic process, negative regulation of transcription from RNA polymerase II promoter, positive regulation of B cell proliferation, positive regulation of fibroblast proliferation, positive regulation of immature T cell proliferation in thymus, positive regulation of ubiquitin-protein ligase activity, regulation of gene expression, rostrocaudal neural tube patterning, segment specification, somatic stem cell division, transcription, DNA-dependent PRC1 complex, PcG protein complex, cytoplasm, nuclear body, nucleolus, nucleus, ubiquitin ligase complex RING-like zinc finger domain binding, chromatin binding, protein binding, sequence-specific DNA binding, ubiquitin-protein ligase activity, zinc ion binding Human Ensembl:ENSMUSP00000028071 BMP1 UniProtKB UniProtKB {GO:0006629=Reactome:REACT_602, GO:0005794=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0005578=GO_REF:0000039, GO:0005576=Reactome:REACT_150462, GO:0007275=PMID:7798260, GO:0044281=Reactome:REACT_111217, GO:0005125=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0001501=PMID:7798260, GO:0001503=GO_REF:0000037, GO:0030198=Reactome:REACT_118779, GO:0001502=PMID:3201241, GO:0042157=Reactome:REACT_13621, GO:0061036=PMID:3201241, GO:0006508=GO_REF:0000038, GO:0008270=GO_REF:0000002, GO:0008233=PMID:12393877, GO:0004222=GO_REF:0000002, GO:0008083=GO_REF:0000037, GO:0008237=PMID:7798260} Q3MIM8 Bone morphogenetic protein 1 protein 20130413 {GO:0006629=TAS, GO:0005794=IEA, GO:0005509=IEA, GO:0005578=IEA, GO:0005576=TAS, GO:0007275=TAS, GO:0044281=TAS, GO:0005125=IEA, GO:0005615=IEA, GO:0030154=IEA, GO:0001501=NAS, GO:0001503=IEA, GO:0030198=TAS, GO:0001502=TAS, GO:0042157=TAS, GO:0061036=IDA, GO:0006508=IEA, GO:0008270=IEA, GO:0008233=IDA, GO:0004222=IEA, GO:0008083=IEA, GO:0008237=NAS} cartilage condensation, cell differentiation, extracellular matrix organization, lipid metabolic process, lipoprotein metabolic process, multicellular organismal development, ossification, positive regulation of cartilage development, proteolysis, skeletal system development, small molecule metabolic process Golgi apparatus, extracellular region, extracellular space, proteinaceous extracellular matrix calcium ion binding, cytokine activity, growth factor activity, metalloendopeptidase activity, metallopeptidase activity, peptidase activity, zinc ion binding Human UniProtKB-KW:KW-0645 BMP10 BHF-UCL UniProtKB {GO:0005515=PMID:17068149, GO:0060045=PMID:10072785, GO:0030018=PMID:17921333, GO:0030308=PMID:17068149, GO:0055010=PMID:10072785, GO:0005615=PMID:17921333, GO:0007512=PMID:10072785, GO:0010614=GO_REF:0000024, GO:0030198=Reactome:REACT_118779, GO:0014898=PMID:17921333, GO:0010613=PMID:17921333, GO:0033612=PMID:17068149, GO:0055009=PMID:10072785, GO:0030336=PMID:17068149, GO:0009986=PMID:17921333, GO:0010862=PMID:16049014, GO:0045214=GO_REF:0000024, GO:0005576=Reactome:REACT_150165, GO:0030509=PMID:17068149, GO:0032924=PMID:17068149, GO:0005125=GO_REF:0000037, GO:2000138=GO_REF:0000024, GO:0060038=GO_REF:0000024, GO:0060347=GO_REF:0000024, GO:0010596=PMID:17068149, GO:0055117=PMID:17921333, GO:0055015=PMID:10072785, GO:0060389=PMID:17068149, GO:0045893=PMID:17068149, GO:0008083=GO_REF:0000037} O95393 Bone morphogenetic protein 10 protein 20120927 {GO:0005515=IPI, GO:0060045=ISS, GO:0030018=IDA, GO:0030308=IDA, GO:0055010=ISS, GO:0005615=IDA, GO:0007512=ISS, GO:0010614=ISS, GO:0030198=TAS, GO:0014898=IC, GO:0010613=IMP, GO:0033612=IDA, GO:0055009=ISS, GO:0030336=IDA, GO:0009986=IDA, GO:0010862=IDA, GO:0045214=ISS, GO:0005576=TAS, GO:0030509=IDA, GO:0032924=IDA, GO:0005125=IEA, GO:2000138=ISS, GO:0060038=ISS, GO:0060347=ISS, GO:0010596=IDA, GO:0055117=IMP, GO:0055015=ISS, GO:0060389=IDA, GO:0045893=IDA, GO:0008083=IEA} BMP signaling pathway, activin receptor signaling pathway, adult heart development, atrial cardiac muscle tissue morphogenesis, cardiac muscle cell proliferation, cardiac muscle hypertrophy in response to stress, extracellular matrix organization, heart trabecula formation, negative regulation of cardiac muscle hypertrophy, negative regulation of cell growth, negative regulation of cell migration, negative regulation of endothelial cell migration, pathway-restricted SMAD protein phosphorylation, positive regulation of cardiac muscle cell proliferation, positive regulation of cardiac muscle hypertrophy, positive regulation of cell proliferation involved in heart morphogenesis, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of transcription, DNA-dependent, regulation of cardiac muscle contraction, sarcomere organization, ventricular cardiac muscle cell development, ventricular cardiac muscle tissue morphogenesis Z disc, cell surface, extracellular region, extracellular space cytokine activity, growth factor activity, protein binding, receptor serine/threonine kinase binding Human BMP15 PINC UniProtKB {GO:0060016=GO_REF:0000002, GO:0001541=GO_REF:0000002, GO:0007292=PMID:9849956, GO:0008083=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037} O95972 Bone morphogenetic protein 15 protein 20030904 {GO:0060016=IEA, GO:0001541=IEA, GO:0007292=TAS, GO:0008083=IEA, GO:0005615=IEA, GO:0005125=IEA} female gamete generation, granulosa cell development, ovarian follicle development extracellular space cytokine activity, growth factor activity Human BMP2 BHF-UCL UniProtKB {GO:0071773=PMID:20843790, GO:0005515=PMID:18184661, GO:0001658=GO_REF:0000024, GO:0003181=GO_REF:0000024, GO:0046332=PMID:18184661, GO:0009790=GO_REF:0000024, GO:0010894=PMID:19584291, GO:0005615=GO_REF:0000019, GO:0003308=PMID:18545679, GO:0007507=GO_REF:0000024, GO:0072138=GO_REF:0000024, GO:1900745=PMID:22540193, GO:0007219=GO_REF:0000024, GO:0030198=Reactome:REACT_118779, GO:0002062=PMID:16194878, GO:0009887=GO_REF:0000024, GO:0070374=PMID:19664780, GO:0033690=GO_REF:0000024, GO:0004745=GO_REF:0000024, GO:0055007=PMID:21311046, GO:0055008=GO_REF:0000024, GO:0048839=GO_REF:0000024, GO:0030501=PMID:18436533, GO:0030335=GO_REF:0000024, GO:0046982=PMID:7811286, GO:0009986=PMID:22227436, GO:2000726=PMID:18545679, GO:0019211=PMID:9213002, GO:0030509=PMID:20843790, GO:0000122=PMID:19736317, GO:0021978=GO_REF:0000024, GO:0045786=PMID:11502704, GO:0001701=GO_REF:0000024, GO:0005125=GO_REF:0000037, GO:0060039=GO_REF:0000024, GO:0001649=PMID:22705305, GO:0003130=PMID:19736317, GO:0001501=PMID:2315314, GO:0045165=GO_REF:0000024, GO:0070700=PMID:7811286, GO:0045600=GO_REF:0000024, GO:0060485=PMID:20890042, GO:0060389=PMID:16049014, GO:0045893=PMID:16049014, GO:0035630=PMID:16433617, GO:0045892=PMID:15254224, GO:0040007=GO_REF:0000002, GO:0008083=GO_REF:0000037, GO:0051042=PMID:16194878, GO:0008285=PMID:19584291, GO:0042482=GO_REF:0000024, GO:0010718=PMID:20890042, GO:0007267=PMID:2315314, GO:0030177=GO_REF:0000024, GO:0060129=GO_REF:0000024, GO:0001837=PMID:18184661, GO:0030282=GO_REF:0000024, GO:0060395=PMID:17244894, GO:0060128=GO_REF:0000024, GO:0045778=PMID:9213002, GO:0021537=PMID:9187146, GO:0031648=GO_REF:0000019, GO:0060317=PMID:18184661, GO:0000187=PMID:17202865, GO:0006954=GO_REF:0000024, GO:0045944=PMID:16433617, GO:0010922=PMID:9213002, GO:0042475=GO_REF:0000024, GO:1901522=PMID:20843790, GO:0090090=PMID:17202865, GO:0001666=GO_REF:0000024, GO:0006355=PMID:15671031, GO:0043065=PMID:9187146, GO:0048762=PMID:9693150, GO:0010862=PMID:19664780, GO:0035054=GO_REF:0000024, GO:0005102=PMID:2315314, GO:0003203=GO_REF:0000024, GO:0060804=GO_REF:0000024, GO:0005576=Reactome:REACT_150165, GO:0035051=PMID:19736317, GO:0006029=GO_REF:0000019, GO:0045669=PMID:16433617, GO:0010628=PMID:16243309, GO:0071407=GO_REF:0000019, GO:0048711=GO_REF:0000024, GO:0043569=PMID:19584291, GO:0001938=PMID:17992660, GO:0045666=GO_REF:0000024, GO:2000065=PMID:19584291, GO:0061036=PMID:3201241, GO:0001934=PMID:17472960, GO:0042487=GO_REF:0000019, GO:0006468=PMID:22540193, GO:0043410=PMID:22540193, GO:0032348=PMID:19584291} P12643 Bone morphogenetic protein 2 protein 20110120 {GO:0071773=IDA, GO:0005515=IPI, GO:0001658=ISS, GO:0003181=ISS, GO:0046332=IDA, GO:0009790=ISS, GO:0010894=IDA, GO:0005615=IEA, GO:0003308=IDA, GO:0007507=ISS, GO:0072138=ISS, GO:1900745=IDA, GO:0007219=ISS, GO:0030198=TAS, GO:0002062=IDA, GO:0009887=ISS, GO:0070374=IMP, GO:0033690=ISS, GO:0004745=ISS, GO:0055007=IMP, GO:0055008=ISS, GO:0048839=ISS, GO:0030501=IDA, GO:0030335=ISS, GO:0046982=IDA, GO:0009986=IDA, GO:2000726=IDA, GO:0019211=IDA, GO:0030509=IDA, GO:0000122=IDA, GO:0021978=ISS, GO:0045786=IDA, GO:0001701=ISS, GO:0005125=IEA, GO:0060039=ISS, GO:0001649=IDA, GO:0003130=IDA, GO:0001501=TAS, GO:0045165=ISS, GO:0070700=IDA, GO:0045600=ISS, GO:0060485=IMP, GO:0060389=IDA, GO:0045893=IDA, GO:0035630=IDA, GO:0045892=IDA, GO:0040007=IEA, GO:0008083=IEA, GO:0051042=IDA, GO:0008285=IDA, GO:0042482=ISS, GO:0010718=IDA, GO:0007267=TAS, GO:0030177=ISS, GO:0060129=ISS, GO:0001837=IDA, GO:0030282=ISS, GO:0060395=IDA, GO:0060128=ISS, GO:0045778=IDA, GO:0021537=IDA, GO:0031648=IEA, GO:0060317=IDA, GO:0000187=IDA, GO:0006954=ISS, GO:0045944=IDA, GO:0010922=IDA, GO:0042475=ISS, GO:1901522=IDA, GO:0090090=IEP, GO:0001666=ISS, GO:0006355=IDA, GO:0043065=IDA, GO:0048762=IDA, GO:0010862=IMP, GO:0035054=ISS, GO:0005102=TAS, GO:0003203=ISS, GO:0060804=ISS, GO:0005576=TAS, GO:0035051=IMP, GO:0006029=IEA, GO:0045669=IDA, GO:0010628=IDA, GO:0071407=IEA, GO:0048711=ISS, GO:0043569=IDA, GO:0001938=IDA, GO:0045666=ISS, GO:2000065=IDA, GO:0061036=IDA, GO:0001934=IDA, GO:0042487=IEA, GO:0006468=IDA, GO:0043410=IDA, GO:0032348=IDA} BMP signaling pathway, BMP signaling pathway involved in heart induction, Notch signaling pathway, SMAD protein signal transduction, activation of MAPK activity, atrioventricular valve morphogenesis, bone mineralization, bone mineralization involved in bone maturation, branching involved in ureteric bud morphogenesis, cardiac epithelial to mesenchymal transition, cardiac muscle cell differentiation, cardiac muscle tissue morphogenesis, cardiocyte differentiation, cell fate commitment, cell-cell signaling, cellular response to BMP stimulus, cellular response to organic cyclic compound, chondrocyte differentiation, corticotropin hormone secreting cell differentiation, embryo development, embryonic heart tube anterior/posterior pattern specification, endocardial cushion morphogenesis, epithelial to mesenchymal transition, extracellular matrix organization, growth, heart development, in utero embryonic development, inflammatory response, inner ear development, mesenchymal cell differentiation, mesenchymal cell proliferation involved in ureteric bud development, mesenchyme development, negative regulation of Wnt receptor signaling pathway involved in heart development, negative regulation of aldosterone biosynthetic process, negative regulation of calcium-independent cell-cell adhesion, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cardiac muscle cell differentiation, negative regulation of cell cycle, negative regulation of cell proliferation, negative regulation of cortisol biosynthetic process, negative regulation of insulin-like growth factor receptor signaling pathway, negative regulation of steroid biosynthetic process, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, odontogenesis of dentin-containing tooth, organ morphogenesis, osteoblast differentiation, pathway-restricted SMAD protein phosphorylation, pericardium development, positive regulation of ERK1 and ERK2 cascade, positive regulation of MAPK cascade, positive regulation of Wnt receptor signaling pathway, positive regulation of Wnt receptor signaling pathway by BMP signaling pathway, positive regulation of apoptotic process, positive regulation of astrocyte differentiation, positive regulation of bone mineralization, positive regulation of cartilage development, positive regulation of cell migration, positive regulation of endothelial cell proliferation, positive regulation of epithelial to mesenchymal transition, positive regulation of fat cell differentiation, positive regulation of gene expression, positive regulation of neuron differentiation, positive regulation of odontogenesis, positive regulation of ossification, positive regulation of osteoblast differentiation, positive regulation of osteoblast proliferation, positive regulation of p38MAPK cascade, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of phosphatase activity, positive regulation of protein phosphorylation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus, positive regulation of transcription, DNA-dependent, protein destabilization, protein phosphorylation, proteoglycan metabolic process, regulation of odontogenesis of dentin-containing tooth, regulation of transcription, DNA-dependent, response to hypoxia, skeletal system development, telencephalon development, telencephalon regionalization, thyroid-stimulating hormone-secreting cell differentiation cell surface, extracellular region, extracellular space BMP receptor binding, SMAD binding, cytokine activity, growth factor activity, phosphatase activator activity, protein binding, protein heterodimerization activity, receptor binding, retinol dehydrogenase activity Human BMP2K HPA UniProtKB {GO:0030500=GO_REF:0000019, GO:0019208=GO_REF:0000019, GO:0004674=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037} Q9NSY1 BMP-2-inducible protein kinase protein 20120912 {GO:0030500=IEA, GO:0019208=IEA, GO:0004674=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005524=IEA} regulation of bone mineralization nucleolus, nucleus ATP binding, phosphatase regulator activity, protein serine/threonine kinase activity NOT Human BMP3 MGI UniProtKB {GO:0001501=PMID:3201241, GO:0001503=GO_REF:0000037, GO:0070700=PMID:7811286, GO:0051216=GO_REF:0000037, GO:0045944=GO_REF:0000019, GO:0007267=PMID:3201241, GO:0005102=PMID:3201241, GO:0008083=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037, GO:0040007=GO_REF:0000002, GO:0030154=GO_REF:0000037} P12645 Bone morphogenetic protein 3 protein 20100311 {GO:0001501=TAS, GO:0001503=IEA, GO:0070700=IPI, GO:0051216=IEA, GO:0045944=IEA, GO:0007267=TAS, GO:0005102=TAS, GO:0008083=IEA, GO:0005615=IEA, GO:0005125=IEA, GO:0040007=IEA, GO:0030154=IEA} cartilage development, cell differentiation, cell-cell signaling, growth, ossification, positive regulation of transcription from RNA polymerase II promoter, skeletal system development extracellular space BMP receptor binding, cytokine activity, growth factor activity, receptor binding Human BMP4 GOC UniProtKB {GO:0005515=PMID:8752214, GO:2000007=PMID:12141440, GO:0034504=PMID:17244894, GO:2000005=PMID:12141440, GO:0003139=PMID:20702560, GO:0009791=PMID:8674409, GO:0048701=GO_REF:0000019, GO:0007281=GO_REF:0000019, GO:0005615=GO_REF:0000024, GO:0045662=PMID:14749725, GO:0002062=GO_REF:0000024, GO:0035990=GO_REF:0000024, GO:0035993=GO_REF:0000024, GO:0060548=PMID:12631064, GO:0060438=PMID:8674409, GO:0090191=PMID:17118062, GO:0090194=PMID:12141440, GO:0060433=PMID:8674409, GO:0010942=PMID:8674409, GO:0061149=GO_REF:0000024, GO:0048392=PMID:10021330, GO:0002320=PMID:12421925, GO:0030501=PMID:18436533, GO:0060235=GO_REF:0000019, GO:0051150=GO_REF:0000019, GO:0070244=PMID:12421925, GO:0072101=PMID:17118062, GO:0003323=PMID:11865031, GO:0072104=GO_REF:0000024, GO:0030509=PMID:18436533, GO:0021978=GO_REF:0000019, GO:0072192=GO_REF:0000024, GO:2000137=PMID:20702560, GO:0005125=PMID:14749725, GO:0042056=PMID:12631064, GO:0045843=PMID:14749725, GO:0072193=GO_REF:0000024, GO:0003130=PMID:20702560, GO:0010595=PMID:17992660, GO:0060442=GO_REF:0000019, GO:0061155=PMID:17992660, GO:0060440=GO_REF:0000019, GO:0060441=PMID:8674409, GO:0032967=PMID:17720811, GO:0061151=GO_REF:0000024, GO:0060449=GO_REF:0000019, GO:0040007=GO_REF:0000002, GO:0072015=GO_REF:0000019, GO:0060592=GO_REF:0000019, GO:0021983=GO_REF:0000019, GO:0021537=PMID:9187146, GO:0060395=PMID:17244894, GO:0060393=PMID:18787191, GO:0000186=PMID:17600318, GO:0072198=GO_REF:0000019, GO:0042476=PMID:11023873, GO:0042475=GO_REF:0000019, GO:0030225=PMID:21149635, GO:0021904=GO_REF:0000019, GO:0030224=PMID:21149635, GO:0072125=PMID:17244894, GO:0060113=GO_REF:0000019, GO:0003197=PMID:18076106, GO:0001822=PMID:18305125, GO:0001823=PMID:18437684, GO:0005578=GO_REF:0000039, GO:0010862=PMID:9389648, GO:0005576=Reactome:REACT_150165, GO:0048663=GO_REF:0000019, GO:0048660=GO_REF:0000019, GO:0048661=PMID:10706139, GO:0050918=PMID:12631064, GO:0045669=PMID:18436533, GO:0042326=PMID:17244894, GO:0003337=PMID:10706139, GO:0071363=GO_REF:0000019, GO:0060197=GO_REF:0000019, GO:0045666=GO_REF:0000019, GO:0030218=GO_REF:0000019, GO:0061036=PMID:3201241, GO:0035116=GO_REF:0000019, GO:0042487=GO_REF:0000019, GO:0048754=PMID:10706139, GO:0033088=PMID:12421925, GO:0001657=PMID:12141440, GO:0001658=PMID:12631064, GO:0033085=PMID:12421925, GO:0050680=GO_REF:0000019, GO:0001759=GO_REF:0000019, GO:0007224=PMID:17850284, GO:0060503=PMID:8674409, GO:0072138=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0048745=GO_REF:0000024, GO:0060502=PMID:8674409, GO:0061047=GO_REF:0000024, GO:0070374=GO_REF:0000019, GO:0055007=GO_REF:0000019, GO:0060684=GO_REF:0000019, GO:0003279=PMID:18076106, GO:0072200=PMID:12399320, GO:0048286=PMID:8674409, GO:0055020=PMID:20702560, GO:0001843=GO_REF:0000019, GO:0000122=PMID:9187146, GO:0045786=PMID:11502704, GO:0072097=PMID:10706139, GO:0060391=PMID:9389648, GO:0072205=GO_REF:0000024, GO:0001649=PMID:17720811, GO:0060686=GO_REF:0000019, GO:0060687=GO_REF:0000019, GO:0045839=PMID:17244894, GO:0001958=GO_REF:0000024, GO:0070700=PMID:7811286, GO:0060272=GO_REF:0000019, GO:0072001=PMID:17850284, GO:0045893=PMID:17992660, GO:0008083=GO_REF:0000037, GO:0045892=PMID:17244894, GO:0045603=GO_REF:0000019, GO:0042733=GO_REF:0000019, GO:0072161=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0008285=PMID:9187146, GO:0090184=PMID:10021330, GO:0060425=PMID:8674409, GO:0002043=PMID:18787191, GO:0045778=PMID:14749725, GO:0030513=GO_REF:0000024, GO:0009948=GO_REF:0000019, GO:0002244=PMID:15451575, GO:0043407=PMID:17244894, GO:0045944=PMID:9187146, GO:0043401=PMID:17244894, GO:0032331=GO_REF:0000019, GO:0008201=GO_REF:0000019, GO:0010159=GO_REF:0000019, GO:0043066=PMID:17992660, GO:0043065=PMID:9187146, GO:0001525=GO_REF:0000019, GO:0003014=GO_REF:0000019, GO:0060363=GO_REF:0000019, GO:0007500=GO_REF:0000019, GO:0001938=PMID:17992660, GO:0010629=GO_REF:0000019, GO:0001934=PMID:14749725, GO:0071893=PMID:10021330, GO:2000105=PMID:15516325} P12644 Bone morphogenetic protein 4 protein 20130413 {GO:0005515=IPI, GO:2000007=IDA, GO:0034504=IDA, GO:2000005=IDA, GO:0003139=IMP, GO:0009791=IDA, GO:0048701=IEA, GO:0007281=IEA, GO:0005615=ISS, GO:0045662=IDA, GO:0002062=ISS, GO:0035990=ISS, GO:0035993=ISS, GO:0060548=IDA, GO:0060438=IDA, GO:0090191=IDA, GO:0090194=IDA, GO:0060433=IDA, GO:0010942=IDA, GO:0061149=ISS, GO:0048392=IDA, GO:0002320=IMP, GO:0030501=IDA, GO:0060235=IEA, GO:0051150=IEA, GO:0070244=IMP, GO:0072101=IDA, GO:0003323=IDA, GO:0072104=ISS, GO:0030509=IDA, GO:0021978=IEA, GO:0072192=ISS, GO:2000137=IMP, GO:0005125=IDA, GO:0042056=IDA, GO:0045843=IDA, GO:0072193=ISS, GO:0003130=IMP, GO:0010595=IDA, GO:0060442=IEA, GO:0061155=IDA, GO:0060440=IEA, GO:0060441=IDA, GO:0032967=IDA, GO:0061151=ISS, GO:0060449=IEA, GO:0040007=IEA, GO:0072015=IEA, GO:0060592=IEA, GO:0021983=IEA, GO:0021537=IDA, GO:0060395=IDA, GO:0060393=IDA, GO:0000186=IDA, GO:0072198=IEA, GO:0042476=IGI, GO:0042475=IEA, GO:0030225=IDA, GO:0021904=IEA, GO:0030224=IDA, GO:0072125=IDA, GO:0060113=IEA, GO:0003197=TAS, GO:0001822=IMP, GO:0001823=IEP, GO:0005578=IEA, GO:0010862=IDA, GO:0005576=TAS, GO:0048663=IEA, GO:0048660=IEA, GO:0048661=IDA, GO:0050918=IDA, GO:0045669=IDA, GO:0042326=IDA, GO:0003337=IDA, GO:0071363=IEA, GO:0060197=IEA, GO:0045666=IEA, GO:0030218=IEA, GO:0061036=IDA, GO:0035116=IEA, GO:0042487=IEA, GO:0048754=IDA, GO:0033088=IMP, GO:0001657=IDA, GO:0001658=IDA, GO:0033085=IMP, GO:0050680=IEA, GO:0001759=IEA, GO:0007224=IEP, GO:0060503=IDA, GO:0072138=IEA, GO:0030198=TAS, GO:0048745=ISS, GO:0060502=IDA, GO:0061047=ISS, GO:0070374=IEA, GO:0055007=IEA, GO:0060684=IEA, GO:0003279=TAS, GO:0072200=IDA, GO:0048286=IDA, GO:0055020=IMP, GO:0001843=IEA, GO:0000122=IDA, GO:0045786=IDA, GO:0072097=IDA, GO:0060391=IDA, GO:0072205=ISS, GO:0001649=IDA, GO:0060686=IEA, GO:0060687=IEA, GO:0045839=IDA, GO:0001958=ISS, GO:0070700=IDA, GO:0060272=IEA, GO:0072001=IEP, GO:0045893=IDA, GO:0008083=IEA, GO:0045892=IDA, GO:0045603=IEA, GO:0042733=IEA, GO:0072161=IEA, GO:0008284=IEA, GO:0008285=IDA, GO:0090184=IDA, GO:0060425=IDA, GO:0002043=IDA, GO:0045778=IDA, GO:0030513=ISS, GO:0009948=IEA, GO:0002244=IDA, GO:0043407=IDA, GO:0045944=IDA, GO:0043401=IMP, GO:0032331=IEA, GO:0008201=IEA, GO:0010159=IEA, GO:0043066=IDA, GO:0043065=IDA, GO:0001525=IEA, GO:0003014=IEA, GO:0060363=IEA, GO:0007500=IEA, GO:0001938=IDA, GO:0010629=IEA, GO:0001934=IDA, GO:0071893=IDA, GO:2000105=IDA} BMP signaling pathway, BMP signaling pathway involved in heart induction, BMP signaling pathway involved in nephric duct formation, BMP signaling pathway involved in renal system segmentation, BMP signaling pathway involved in ureter morphogenesis, SMAD protein signal transduction, activation of MAPKK activity, angiogenesis, anterior/posterior axis specification, blood vessel endothelial cell proliferation involved in sprouting angiogenesis, branching involved in prostate gland morphogenesis, branching involved in ureteric bud morphogenesis, branching morphogenesis of an epithelial tube, bronchus development, bud dilation involved in lung branching, bud elongation involved in lung branching, cardiac muscle cell differentiation, cardiac septum development, cellular response to growth factor stimulus, chondrocyte differentiation, cloacal septation, cranial suture morphogenesis, deltoid tuberosity development, dorsal/ventral neural tube patterning, embryonic cranial skeleton morphogenesis, embryonic digit morphogenesis, embryonic hindlimb morphogenesis, embryonic skeletal joint morphogenesis, endocardial cushion development, endochondral ossification, epithelial cell proliferation involved in lung morphogenesis, epithelial tube branching involved in lung morphogenesis, epithelial-mesenchymal cell signaling, erythrocyte differentiation, extracellular matrix organization, germ cell development, glomerular capillary formation, glomerular visceral epithelial cell development, growth, hematopoietic progenitor cell differentiation, inner ear receptor cell differentiation, intermediate mesodermal cell differentiation, kidney development, lens induction in camera-type eye, lung alveolus development, lung morphogenesis, lymphoid progenitor cell differentiation, macrophage differentiation, mammary gland formation, mesenchymal cell differentiation involved in kidney development, mesenchymal cell proliferation involved in ureter development, mesenchymal cell proliferation involved in ureteric bud development, mesenchymal to epithelial transition involved in metanephros morphogenesis, mesodermal cell fate determination, mesonephros development, metanephric collecting duct development, monocyte differentiation, negative regulation of MAP kinase activity, negative regulation of T cell differentiation in thymus, negative regulation of apoptotic process, negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway, negative regulation of branching involved in ureteric bud morphogenesis, negative regulation of cell cycle, negative regulation of cell death, negative regulation of cell proliferation, negative regulation of cell proliferation involved in heart morphogenesis, negative regulation of chondrocyte differentiation, negative regulation of epithelial cell proliferation, negative regulation of gene expression, negative regulation of glomerular mesangial cell proliferation, negative regulation of glomerulus development, negative regulation of immature T cell proliferation in thymus, negative regulation of mesenchymal cell proliferation involved in ureter development, negative regulation of metanephric S-shaped body morphogenesis, negative regulation of metanephric comma-shaped body morphogenesis, negative regulation of mitosis, negative regulation of myoblast differentiation, negative regulation of phosphorylation, negative regulation of prostatic bud formation, negative regulation of striated muscle tissue development, negative regulation of thymocyte apoptotic process, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, neural tube closure, neuron fate commitment, odontogenesis, odontogenesis of dentin-containing tooth, organ induction, osteoblast differentiation, pituitary gland development, positive chemotaxis, positive regulation of BMP signaling pathway, positive regulation of DNA-dependent DNA replication, positive regulation of ERK1 and ERK2 cascade, positive regulation of SMAD protein import into nucleus, positive regulation of apoptotic process, positive regulation of bone mineralization, positive regulation of branching involved in lung morphogenesis, positive regulation of cardiac muscle fiber development, positive regulation of cartilage development, positive regulation of cell death, positive regulation of cell proliferation, positive regulation of collagen biosynthetic process, positive regulation of endothelial cell differentiation, positive regulation of endothelial cell migration, positive regulation of endothelial cell proliferation, positive regulation of kidney development, positive regulation of neuron differentiation, positive regulation of ossification, positive regulation of osteoblast differentiation, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of protein phosphorylation, positive regulation of smooth muscle cell proliferation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, post-embryonic development, protein localization to nucleus, pulmonary artery endothelial tube morphogenesis, regulation of branching involved in prostate gland morphogenesis, regulation of odontogenesis of dentin-containing tooth, regulation of pathway-restricted SMAD protein phosphorylation, regulation of smooth muscle cell differentiation, regulation of smooth muscle cell proliferation, renal system development, renal system process, secondary heart field specification, smooth muscle tissue development, smoothened signaling pathway, specification of organ position, specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway, steroid hormone mediated signaling pathway, telencephalon development, telencephalon regionalization, tendon cell differentiation, trachea development, trachea formation, type B pancreatic cell development, ureter epithelial cell differentiation, ureter smooth muscle cell differentiation, ureteric bud development extracellular region, extracellular space, proteinaceous extracellular matrix BMP receptor binding, chemoattractant activity, cytokine activity, growth factor activity, heparin binding, protein binding Human BMP5 BHF-UCL UniProtKB {GO:0008285=PMID:19584291, GO:0051216=GO_REF:0000037, GO:0031988=GO_REF:0000024, GO:0003323=PMID:11865031, GO:0005576=GO_REF:0000038, GO:0010719=PMID:21319131, GO:0005575=GO_REF:0000015, GO:0005615=GO_REF:0000024, GO:0010894=PMID:19584291, GO:0005125=GO_REF:0000029, GO:0001501=PMID:2263636, GO:0001503=GO_REF:0000037, GO:0043569=PMID:19584291, GO:0070700=PMID:7811286, GO:2000065=PMID:19584291, GO:2000105=PMID:15516325, GO:0040007=GO_REF:0000002, GO:0008083=GO_REF:0000037, GO:0032348=PMID:19584291} P22003 Bone morphogenetic protein 5 protein 20120503 {GO:0008285=IDA, GO:0051216=IEA, GO:0031988=ISS, GO:0003323=IDA, GO:0005576=IEA, GO:0010719=NAS, GO:0005575=ND, GO:0005615=ISS, GO:0010894=IDA, GO:0005125=NAS, GO:0001501=NAS, GO:0001503=IEA, GO:0043569=IDA, GO:0070700=IPI, GO:2000065=IDA, GO:2000105=IDA, GO:0040007=IEA, GO:0008083=IEA, GO:0032348=IDA} cartilage development, growth, negative regulation of aldosterone biosynthetic process, negative regulation of cell proliferation, negative regulation of cortisol biosynthetic process, negative regulation of epithelial to mesenchymal transition, negative regulation of insulin-like growth factor receptor signaling pathway, negative regulation of steroid biosynthetic process, ossification, positive regulation of DNA-dependent DNA replication, skeletal system development, type B pancreatic cell development cellular_component, extracellular region, extracellular space, membrane-bounded vesicle BMP receptor binding, cytokine activity, growth factor activity Human UniProtKB:D4A7P9 BMP6 BHF-UCL UniProtKB {GO:0051216=GO_REF:0000037, GO:0001654=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0060395=PMID:17244894, GO:0030539=GO_REF:0000019, GO:0006955=PMID:16886151, GO:0005737=GO_REF:0000019, GO:0006954=GO_REF:0000019, GO:0045944=PMID:16527843, GO:0032526=GO_REF:0000019, GO:0030501=PMID:18436533, GO:0046982=PMID:7811286, GO:0001822=GO_REF:0000019, GO:0031988=GO_REF:0000019, GO:0010862=PMID:17244894, GO:0003323=PMID:11865031, GO:0051384=GO_REF:0000019, GO:0030509=PMID:18436533, GO:0005125=GO_REF:0000037, GO:0001649=GO_REF:0000019, GO:0045669=PMID:18436533, GO:0001501=PMID:8089189, GO:0001958=GO_REF:0000019, GO:0001938=GO_REF:0000019, GO:0045666=GO_REF:0000019, GO:0070700=PMID:7811286, GO:2000105=PMID:15516325, GO:0040007=GO_REF:0000002, GO:0045603=GO_REF:0000019, GO:0008083=GO_REF:0000037, GO:0032349=PMID:16527843} P22004 Bone morphogenetic protein 6 protein 20120501 {GO:0051216=IEA, GO:0001654=IEA, GO:0005615=IEA, GO:0060395=IDA, GO:0030539=IEA, GO:0006955=IMP, GO:0005737=IEA, GO:0006954=IEA, GO:0045944=IDA, GO:0032526=IEA, GO:0030501=IDA, GO:0046982=IDA, GO:0001822=IEA, GO:0031988=IEA, GO:0010862=IDA, GO:0003323=IDA, GO:0051384=IEA, GO:0030509=IDA, GO:0005125=IEA, GO:0001649=IEA, GO:0045669=IDA, GO:0001501=TAS, GO:0001958=IEA, GO:0001938=IEA, GO:0045666=IEA, GO:0070700=IPI, GO:2000105=NAS, GO:0040007=IEA, GO:0045603=IEA, GO:0008083=IEA, GO:0032349=IDA} BMP signaling pathway, SMAD protein signal transduction, cartilage development, endochondral ossification, eye development, growth, immune response, inflammatory response, kidney development, male genitalia development, osteoblast differentiation, positive regulation of DNA-dependent DNA replication, positive regulation of aldosterone biosynthetic process, positive regulation of bone mineralization, positive regulation of endothelial cell differentiation, positive regulation of endothelial cell proliferation, positive regulation of neuron differentiation, positive regulation of osteoblast differentiation, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of transcription from RNA polymerase II promoter, response to glucocorticoid stimulus, response to retinoic acid, skeletal system development, type B pancreatic cell development cytoplasm, extracellular space, membrane-bounded vesicle BMP receptor binding, cytokine activity, growth factor activity, protein heterodimerization activity Human BMP7 BHF-UCL UniProtKB {GO:0005515=PMID:18184661, GO:0001656=PMID:18437684, GO:0001657=GO_REF:0000024, GO:0034504=PMID:17244894, GO:0051216=GO_REF:0000037, GO:0005615=PMID:17977014, GO:0048596=GO_REF:0000019, GO:0009880=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0007411=GO_REF:0000019, GO:0060548=PMID:12631064, GO:0072040=GO_REF:0000019, GO:0034116=PMID:15100360, GO:0072136=GO_REF:0000019, GO:0072134=GO_REF:0000019, GO:0010664=GO_REF:0000024, GO:0072133=GO_REF:0000019, GO:0045746=GO_REF:0000019, GO:0030501=PMID:18436533, GO:0001707=GO_REF:0000019, GO:0030509=PMID:18436533, GO:0045786=PMID:11502704, GO:0005125=GO_REF:0000037, GO:0060686=GO_REF:0000019, GO:0060687=GO_REF:0000019, GO:0045839=PMID:17244894, GO:0001501=PMID:2357959, GO:0001503=GO_REF:0000037, GO:0060272=GO_REF:0000019, GO:0070487=PMID:15100360, GO:0060485=GO_REF:0000024, GO:0045893=PMID:16049014, GO:0040007=GO_REF:0000002, GO:0008083=GO_REF:0000037, GO:0045892=PMID:17244894, GO:0060445=GO_REF:0000019, GO:0042347=GO_REF:0000024, GO:0030326=GO_REF:0000019, GO:0001837=PMID:14679171, GO:0060395=PMID:17244894, GO:2000121=GO_REF:0000024, GO:0060393=PMID:16049014, GO:1900106=PMID:15100360, GO:0050768=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0043407=PMID:17244894, GO:0030855=GO_REF:0000019, GO:0043401=PMID:17244894, GO:0042475=GO_REF:0000019, GO:0072125=PMID:17244894, GO:0043065=GO_REF:0000019, GO:0001823=PMID:18437684, GO:0048762=PMID:9693150, GO:0010862=PMID:19736306, GO:0071456=GO_REF:0000024, GO:0032088=GO_REF:0000024, GO:0005576=Reactome:REACT_150165, GO:0045669=PMID:18436533, GO:0042326=PMID:17244894, GO:0045665=PMID:16325379, GO:0045666=GO_REF:0000019, GO:0048812=PMID:16325379, GO:0048754=GO_REF:0000019} P18075 Bone morphogenetic protein 7 protein 20120312 {GO:0005515=IPI, GO:0001656=IEP, GO:0001657=ISS, GO:0034504=IDA, GO:0051216=IEA, GO:0005615=IDA, GO:0048596=IEA, GO:0009880=IEA, GO:0030198=TAS, GO:0007411=IEA, GO:0060548=IDA, GO:0072040=IEA, GO:0034116=IDA, GO:0072136=IEA, GO:0072134=IEA, GO:0010664=ISS, GO:0072133=IEA, GO:0045746=IEA, GO:0030501=IDA, GO:0001707=IEA, GO:0030509=IDA, GO:0045786=IDA, GO:0005125=IEA, GO:0060686=IEA, GO:0060687=IEA, GO:0045839=IDA, GO:0001501=TAS, GO:0001503=IEA, GO:0060272=IEA, GO:0070487=IDA, GO:0060485=ISS, GO:0045893=IDA, GO:0040007=IEA, GO:0008083=IEA, GO:0045892=IDA, GO:0060445=IEA, GO:0042347=ISS, GO:0030326=IEA, GO:0001837=TAS, GO:0060395=IDA, GO:2000121=ISS, GO:0060393=IDA, GO:1900106=IDA, GO:0050768=IEA, GO:0045944=IEA, GO:0043407=IDA, GO:0030855=IEA, GO:0043401=IMP, GO:0042475=IEA, GO:0072125=IDA, GO:0043065=IEA, GO:0001823=IEP, GO:0048762=IDA, GO:0010862=IDA, GO:0071456=ISS, GO:0032088=ISS, GO:0005576=TAS, GO:0045669=IDA, GO:0042326=IDA, GO:0045665=IDA, GO:0045666=IEA, GO:0048812=IDA, GO:0048754=IEA} BMP signaling pathway, SMAD protein signal transduction, axon guidance, branching involved in salivary gland morphogenesis, branching morphogenesis of an epithelial tube, cartilage development, cellular response to hypoxia, embryonic camera-type eye morphogenesis, embryonic limb morphogenesis, embryonic pattern specification, embryonic skeletal joint morphogenesis, epithelial cell differentiation, epithelial to mesenchymal transition, extracellular matrix organization, growth, mesenchymal cell differentiation, mesenchyme development, mesoderm formation, mesonephros development, metanephric mesenchymal cell proliferation involved in metanephros development, metanephric mesenchyme morphogenesis, metanephros development, monocyte aggregation, negative regulation of MAP kinase activity, negative regulation of NF-kappaB import into nucleus, negative regulation of NF-kappaB transcription factor activity, negative regulation of Notch signaling pathway, negative regulation of cell cycle, negative regulation of cell death, negative regulation of glomerular mesangial cell proliferation, negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis, negative regulation of mitosis, negative regulation of neurogenesis, negative regulation of neuron differentiation, negative regulation of phosphorylation, negative regulation of prostatic bud formation, negative regulation of striated muscle cell apoptotic process, negative regulation of transcription, DNA-dependent, nephrogenic mesenchyme morphogenesis, neuron projection morphogenesis, odontogenesis of dentin-containing tooth, ossification, positive regulation of apoptotic process, positive regulation of bone mineralization, positive regulation of heterotypic cell-cell adhesion, positive regulation of hyaluranon cable assembly, positive regulation of neuron differentiation, positive regulation of osteoblast differentiation, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein localization to nucleus, regulation of branching involved in prostate gland morphogenesis, regulation of pathway-restricted SMAD protein phosphorylation, regulation of removal of superoxide radicals, skeletal system development, steroid hormone mediated signaling pathway, ureteric bud development extracellular region, extracellular space cytokine activity, growth factor activity, protein binding Human BMP8A UniProtKB UniProtKB {GO:0001503=GO_REF:0000037, GO:0051216=GO_REF:0000037, GO:0008083=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037, GO:0040007=GO_REF:0000002, GO:0030154=GO_REF:0000037} Q7Z5Y6 Bone morphogenetic protein 8A protein 20130413 {GO:0001503=IEA, GO:0051216=IEA, GO:0008083=IEA, GO:0005615=IEA, GO:0005125=IEA, GO:0040007=IEA, GO:0030154=IEA} cartilage development, cell differentiation, growth, ossification extracellular space cytokine activity, growth factor activity Human UniProtKB-KW:KW-0891 BMP8B PINC UniProtKB {GO:0001501=PMID:1460021, GO:0001503=GO_REF:0000037, GO:0051216=GO_REF:0000037, GO:0005576=GO_REF:0000038, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037, GO:0008083=GO_REF:0000037, GO:0040007=GO_REF:0000002, GO:0030154=GO_REF:0000037} P34820 Bone morphogenetic protein 8B protein 20030904 {GO:0001501=TAS, GO:0001503=IEA, GO:0051216=IEA, GO:0005576=IEA, GO:0005615=IEA, GO:0005125=IEA, GO:0008083=IEA, GO:0040007=IEA, GO:0030154=IEA} cartilage development, cell differentiation, growth, ossification, skeletal system development extracellular region, extracellular space cytokine activity, growth factor activity Human BMPER BHF-UCL UniProtKB {GO:0030514=PMID:18787191, GO:0001657=GO_REF:0000019, GO:0048839=GO_REF:0000019, GO:0010594=PMID:18787191, GO:0002043=PMID:18787191, GO:0042118=PMID:18787191, GO:0070374=PMID:18787191, GO:0005615=PMID:18787191, GO:0060393=PMID:18787191} Q8N8U9 BMP-binding endothelial regulator protein protein 20100520 {GO:0030514=TAS, GO:0001657=IEA, GO:0048839=IEA, GO:0010594=IDA, GO:0002043=IDA, GO:0042118=IDA, GO:0070374=IDA, GO:0005615=IDA, GO:0060393=IDA} blood vessel endothelial cell proliferation involved in sprouting angiogenesis, endothelial cell activation, inner ear development, negative regulation of BMP signaling pathway, positive regulation of ERK1 and ERK2 cascade, regulation of endothelial cell migration, regulation of pathway-restricted SMAD protein phosphorylation, ureteric bud development extracellular space Human BMPR1A BHF-UCL UniProtKB {GO:0035137=GO_REF:0000019, GO:0005515=PMID:18184661, GO:0051216=GO_REF:0000019, GO:0000981=GO_REF:0000019, GO:0001756=GO_REF:0000019, GO:0046332=PMID:12065756, GO:0042803=PMID:18436533, GO:0048589=GO_REF:0000019, GO:0060914=GO_REF:0000019, GO:0014032=GO_REF:0000019, GO:0048352=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0007179=PMID:8397373, GO:0050679=GO_REF:0000019, GO:0001707=GO_REF:0000019, GO:0030501=PMID:18436533, GO:0003272=GO_REF:0000024, GO:0030509=PMID:18436533, GO:0001701=GO_REF:0000019, GO:0060391=PMID:9389648, GO:0045893=GO_REF:0000019, GO:0042733=GO_REF:0000019, GO:0048382=GO_REF:0000019, GO:0005886=PMID:15657086, GO:0030324=GO_REF:0000019, GO:0021983=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0009950=GO_REF:0000019, GO:0048378=GO_REF:0000019, GO:0006955=PMID:16886151, GO:0050768=GO_REF:0000019, GO:0048568=GO_REF:0000019, GO:0001880=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:0042475=GO_REF:0000019, GO:0005024=GO_REF:0000002, GO:0021998=GO_REF:0000019, GO:0010862=PMID:9389648, GO:0002053=GO_REF:0000019, GO:0007398=GO_REF:0000019, GO:0005524=PMID:12065756, GO:0045669=PMID:18436533, GO:0048368=GO_REF:0000019, GO:0004674=PMID:12065756, GO:0019827=GO_REF:0000019, GO:0004675=Reactome:REACT_12052, GO:0005901=PMID:15657086, GO:0006468=PMID:12065756, GO:0016021=GO_REF:0000037} P36894 Bone morphogenetic protein receptor type-1A protein 20120925 {GO:0035137=IEA, GO:0005515=IPI, GO:0051216=IEA, GO:0000981=IEA, GO:0001756=IEA, GO:0046332=IDA, GO:0042803=IDA, GO:0048589=IEA, GO:0060914=IEA, GO:0014032=IEA, GO:0048352=IEA, GO:0043025=IEA, GO:0007179=TAS, GO:0050679=IEA, GO:0001707=IEA, GO:0030501=IMP, GO:0003272=ISS, GO:0030509=IDA, GO:0001701=IEA, GO:0060391=IDA, GO:0045893=IEA, GO:0042733=IEA, GO:0048382=IEA, GO:0005886=IDA, GO:0030324=IEA, GO:0021983=IEA, GO:0030425=IEA, GO:0046872=IEA, GO:0009950=IEA, GO:0048378=IEA, GO:0006955=IMP, GO:0050768=IEA, GO:0048568=IEA, GO:0001880=IEA, GO:0060021=IEA, GO:0042475=IEA, GO:0005024=IEA, GO:0021998=IEA, GO:0010862=IDA, GO:0002053=IEA, GO:0007398=IEA, GO:0005524=IDA, GO:0045669=IMP, GO:0048368=IEA, GO:0004674=IDA, GO:0019827=IEA, GO:0004675=TAS, GO:0005901=IMP, GO:0006468=IDA, GO:0016021=IEA} BMP signaling pathway, Mullerian duct regression, cartilage development, developmental growth, dorsal/ventral axis specification, ectoderm development, embryonic digit morphogenesis, embryonic organ development, endocardial cushion formation, heart formation, hindlimb morphogenesis, immune response, in utero embryonic development, lateral mesoderm development, lung development, mesendoderm development, mesoderm formation, negative regulation of neurogenesis, neural crest cell development, neural plate mediolateral regionalization, odontogenesis of dentin-containing tooth, palate development, paraxial mesoderm structural organization, pituitary gland development, positive regulation of SMAD protein import into nucleus, positive regulation of bone mineralization, positive regulation of epithelial cell proliferation, positive regulation of mesenchymal cell proliferation, positive regulation of osteoblast differentiation, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of transcription, DNA-dependent, protein phosphorylation, regulation of lateral mesodermal cell fate specification, somitogenesis, stem cell maintenance, transforming growth factor beta receptor signaling pathway caveola, dendrite, integral to membrane, neuronal cell body, plasma membrane ATP binding, SMAD binding, metal ion binding, protein binding, protein homodimerization activity, protein serine/threonine kinase activity, sequence-specific DNA binding RNA polymerase II transcription factor activity, transforming growth factor beta-activated receptor activity, transmembrane receptor protein serine/threonine kinase activity Human UniProtKB:P36895 BMPR1B BHF-UCL UniProtKB {GO:0031290=GO_REF:0000019, GO:0005515=PMID:18184661, GO:0060041=GO_REF:0000019, GO:0005886=Reactome:REACT_115888, GO:0001654=GO_REF:0000024, GO:0045597=PMID:14523231, GO:0042698=GO_REF:0000024, GO:0046332=PMID:12065756, GO:0009953=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0006954=GO_REF:0000019, GO:0004702=GO_REF:0000002, GO:0005024=GO_REF:0000002, GO:0035108=PMID:14523231, GO:0005025=GO_REF:0000019, GO:0030501=PMID:18436533, GO:0030509=PMID:18436533, GO:0005524=PMID:12065756, GO:0045669=PMID:18436533, GO:0043235=PMID:14523231, GO:0001501=PMID:14523231, GO:0016020=GO_REF:0000002, GO:0001502=PMID:14523231, GO:0005887=PMID:14523231, GO:0004674=PMID:12065756, GO:0004675=PMID:14523231, GO:0001550=GO_REF:0000024, GO:0006468=PMID:12065756} O00238 Bone morphogenetic protein receptor type-1B protein 20080822 {GO:0031290=IEA, GO:0005515=IPI, GO:0060041=IEA, GO:0005886=TAS, GO:0001654=ISS, GO:0045597=IMP, GO:0042698=ISS, GO:0046332=IDA, GO:0009953=IEA, GO:0046872=IEA, GO:0006954=IEA, GO:0004702=IEA, GO:0005024=IEA, GO:0035108=IMP, GO:0005025=IEA, GO:0030501=IMP, GO:0030509=IDA, GO:0005524=IDA, GO:0045669=IMP, GO:0043235=TAS, GO:0001501=IMP, GO:0016020=IEA, GO:0001502=NAS, GO:0005887=IC, GO:0004674=IDA, GO:0004675=IMP, GO:0001550=ISS, GO:0006468=IDA} BMP signaling pathway, cartilage condensation, dorsal/ventral pattern formation, eye development, inflammatory response, limb morphogenesis, ovarian cumulus expansion, ovulation cycle, positive regulation of bone mineralization, positive regulation of cell differentiation, positive regulation of osteoblast differentiation, protein phosphorylation, retina development in camera-type eye, retinal ganglion cell axon guidance, skeletal system development integral to plasma membrane, membrane, plasma membrane, receptor complex ATP binding, SMAD binding, metal ion binding, protein binding, protein serine/threonine kinase activity, receptor signaling protein serine/threonine kinase activity, transforming growth factor beta receptor activity, type I, transforming growth factor beta-activated receptor activity, transmembrane receptor protein serine/threonine kinase activity Human UniProtKB:P12643 BMPR2 BHF-UCL UniProtKB {GO:0005515=PMID:12045205, GO:0030308=PMID:12819188, GO:0014916=PMID:18364108, GO:0005886=PMID:15657086, GO:0006366=PMID:12045205, GO:0061298=GO_REF:0000024, GO:0009952=GO_REF:0000024, GO:0060836=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0016362=Reactome:REACT_12070, GO:0001946=GO_REF:0000024, GO:0030513=PMID:17992660, GO:0045906=GO_REF:0000024, GO:0042127=PMID:11502704, GO:0007178=PMID:12045205, GO:0005024=GO_REF:0000002, GO:0003085=PMID:18364108, GO:0009267=PMID:15657086, GO:0048010=GO_REF:0000024, GO:0030501=PMID:18436533, GO:0001707=GO_REF:0000024, GO:0048286=GO_REF:0000024, GO:0009986=GO_REF:0000019, GO:0010862=PMID:17992660, GO:0030509=PMID:19366699, GO:0005524=GO_REF:0000037, GO:0045669=PMID:18436533, GO:0010595=PMID:17992660, GO:0001938=PMID:17992660, GO:0016020=GO_REF:0000002, GO:0005887=PMID:12045205, GO:0005901=PMID:15657086, GO:0001934=PMID:17472960, GO:0010634=PMID:12819188} Q13873 Bone morphogenetic protein receptor type-2 protein 20120319 {GO:0005515=IPI, GO:0030308=IDA, GO:0014916=IMP, GO:0005886=IDA, GO:0006366=IMP, GO:0061298=ISS, GO:0009952=ISS, GO:0060836=ISS, GO:0046872=IEA, GO:0016362=TAS, GO:0001946=ISS, GO:0030513=IMP, GO:0045906=ISS, GO:0042127=IMP, GO:0007178=IDA, GO:0005024=IEA, GO:0003085=IMP, GO:0009267=IEP, GO:0048010=ISS, GO:0030501=IMP, GO:0001707=ISS, GO:0048286=ISS, GO:0009986=IEA, GO:0010862=IMP, GO:0030509=IMP, GO:0005524=IEA, GO:0045669=IMP, GO:0010595=IMP, GO:0001938=IMP, GO:0016020=IEA, GO:0005887=IDA, GO:0005901=IMP, GO:0001934=IMP, GO:0010634=IDA} BMP signaling pathway, anterior/posterior pattern specification, cellular response to starvation, lung alveolus development, lymphangiogenesis, lymphatic endothelial cell differentiation, mesoderm formation, negative regulation of cell growth, negative regulation of systemic arterial blood pressure, negative regulation of vasoconstriction, positive regulation of BMP signaling pathway, positive regulation of bone mineralization, positive regulation of endothelial cell migration, positive regulation of endothelial cell proliferation, positive regulation of epithelial cell migration, positive regulation of osteoblast differentiation, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of protein phosphorylation, regulation of cell proliferation, regulation of lung blood pressure, retina vasculature development in camera-type eye, transcription from RNA polymerase II promoter, transmembrane receptor protein serine/threonine kinase signaling pathway, vascular endothelial growth factor receptor signaling pathway caveola, cell surface, integral to plasma membrane, membrane, plasma membrane ATP binding, activin receptor activity, type II, metal ion binding, protein binding, transforming growth factor beta-activated receptor activity Human UniProtKB:O35607 BMS1 HPA UniProtKB {GO:0042255=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0003924=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0005525=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q14692 Ribosome biogenesis protein BMS1 homolog protein 20110516 {GO:0042255=ISS, GO:0005730=IDA, GO:0003924=IEA, GO:0005634=IDA, GO:0005525=IEA, GO:0005524=IEA} ribosome assembly nucleolus, nucleus ATP binding, GTP binding, GTPase activity Human BMX IntAct UniProtKB {GO:0005515=PMID:16186805, GO:0006950=GO_REF:0000037, GO:0006915=Reactome:REACT_578, GO:0032587=PMID:11331870, GO:0005524=GO_REF:0000037, GO:0006921=Reactome:REACT_995, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_13417, GO:0035556=GO_REF:0000002, GO:0007165=PMID:11331870, GO:0005543=GO_REF:0000002, GO:0046777=PMID:11331870, GO:0006468=PMID:7970727, GO:0007498=PMID:9520419, GO:0004871=PMID:9520419, GO:0004713=PMID:7970727, GO:0007155=GO_REF:0000037, GO:0004715=PMID:11331870} P51813 Cytoplasmic tyrosine-protein kinase BMX protein 20130415 {GO:0005515=IPI, GO:0006950=IEA, GO:0006915=TAS, GO:0032587=IDA, GO:0005524=IEA, GO:0006921=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0035556=IEA, GO:0007165=IDA, GO:0005543=IEA, GO:0046777=IDA, GO:0006468=TAS, GO:0007498=TAS, GO:0004871=TAS, GO:0004713=TAS, GO:0007155=IEA, GO:0004715=IDA} apoptotic process, cell adhesion, cellular component disassembly involved in execution phase of apoptosis, intracellular signal transduction, mesoderm development, protein autophosphorylation, protein phosphorylation, response to stress, signal transduction cytosol, ruffle membrane ATP binding, metal ion binding, non-membrane spanning protein tyrosine kinase activity, phospholipid binding, protein binding, protein tyrosine kinase activity, signal transducer activity Human UniProtKB:P11309 BNC1 PINC UniProtKB {GO:0050679=GO_REF:0000019, GO:0051276=GO_REF:0000019, GO:0008284=PMID:8034748, GO:0003700=PMID:9099851, GO:0006357=GO_REF:0000019, GO:0006356=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0008544=PMID:1332044, GO:0042060=GO_REF:0000019, GO:0008270=GO_REF:0000002} Q01954 Zinc finger protein basonuclin-1 protein 20030904 {GO:0050679=IEA, GO:0051276=IEA, GO:0008284=TAS, GO:0003700=TAS, GO:0006357=IEA, GO:0006356=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0005737=IEA, GO:0008544=TAS, GO:0042060=IEA, GO:0008270=IEA} chromosome organization, epidermis development, positive regulation of cell proliferation, positive regulation of epithelial cell proliferation, regulation of transcription from RNA polymerase I promoter, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent, wound healing cytoplasm, nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human BNC2 HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q6ZN30 Zinc finger protein basonuclin-2 protein 20090616 {GO:0006355=IEA, GO:0005737=IDA, GO:0005886=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus, plasma membrane DNA binding, zinc ion binding Human BNIP1 HGNC UniProtKB {GO:0005515=PMID:15272311, GO:0043066=PMID:7954800, GO:0005783=PMID:15272311, GO:0006914=GO_REF:0000037, GO:0031201=PMID:15272311, GO:0006915=PMID:7954800, GO:0030176=PMID:15272311, GO:0005635=PMID:7954800, GO:0006917=PMID:15272311, GO:0043231=PMID:7954800, GO:0005739=GO_REF:0000039, GO:0005737=PMID:7954800, GO:0016320=PMID:15272311, GO:0016192=GO_REF:0000037, GO:0007029=PMID:15272311} Q12981 Vesicle transport protein SEC20 protein 20060522 {GO:0005515=IPI, GO:0043066=TAS, GO:0005783=IDA, GO:0006914=IEA, GO:0031201=IDA, GO:0006915=IPI, GO:0030176=TAS, GO:0005635=IDA, GO:0006917=IMP, GO:0043231=IDA, GO:0005739=IEA, GO:0005737=IDA, GO:0016320=IMP, GO:0016192=IEA, GO:0007029=IMP} apoptotic process, autophagy, endoplasmic reticulum membrane fusion, endoplasmic reticulum organization, induction of apoptosis, negative regulation of apoptotic process, vesicle-mediated transport SNARE complex, cytoplasm, endoplasmic reticulum, integral to endoplasmic reticulum membrane, intracellular membrane-bounded organelle, mitochondrion, nuclear envelope protein binding Human UniProtKB:Q9P2W9 BNIP2 GOC UniProtKB {GO:0005515=PMID:10381623, GO:0043066=PMID:7954800, GO:0048471=GO_REF:0000039, GO:0005814=GO_REF:0000019, GO:0051057=GO_REF:0000019, GO:0001824=GO_REF:0000019, GO:0005509=PMID:7954800, GO:0006915=PMID:7954800, GO:0005635=PMID:7954800, GO:0005829=Reactome:REACT_21288, GO:0043231=PMID:7954800, GO:0043547=PMID:10799524, GO:0042692=Reactome:REACT_21303, GO:0005737=PMID:7954800, GO:0051149=Reactome:REACT_21402, GO:0045666=GO_REF:0000019, GO:0031616=GO_REF:0000019, GO:0043410=GO_REF:0000019, GO:0051300=GO_REF:0000019, GO:0051146=GO_REF:0000019, GO:0005096=PMID:10799524} Q12982 BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 protein 20130413 {GO:0005515=IPI, GO:0043066=TAS, GO:0048471=IEA, GO:0005814=IEA, GO:0051057=IEA, GO:0001824=IEA, GO:0005509=TAS, GO:0006915=IPI, GO:0005635=IDA, GO:0005829=TAS, GO:0043231=IDA, GO:0043547=TAS, GO:0042692=TAS, GO:0005737=IDA, GO:0051149=TAS, GO:0045666=IEA, GO:0031616=IEA, GO:0043410=IEA, GO:0051300=IEA, GO:0051146=IEA, GO:0005096=TAS} apoptotic process, blastocyst development, muscle cell differentiation, negative regulation of apoptotic process, positive regulation of GTPase activity, positive regulation of MAPK cascade, positive regulation of muscle cell differentiation, positive regulation of neuron differentiation, positive regulation of small GTPase mediated signal transduction, spindle pole body organization, striated muscle cell differentiation centriole, cytoplasm, cytosol, intracellular membrane-bounded organelle, nuclear envelope, perinuclear region of cytoplasm, spindle pole centrosome GTPase activator activity, calcium ion binding, protein binding Human BNIP3 BHF-UCL UniProtKB {GO:0005515=PMID:19060904, GO:0008219=PMID:10891486, GO:0048102=GO_REF:0000019, GO:0070301=GO_REF:0000019, GO:0005741=PMID:22292033, GO:0005634=GO_REF:0000052, GO:0005635=PMID:7954800, GO:0005740=GO_REF:0000002, GO:0090141=PMID:20436456, GO:0051402=GO_REF:0000024, GO:0042803=PMID:9396766, GO:0030425=GO_REF:0000024, GO:0042802=PMID:16189514, GO:0005739=GO_REF:0000052, GO:0051607=PMID:9973195, GO:0005737=GO_REF:0000024, GO:0043243=PMID:20436456, GO:0071279=PMID:20436456, GO:0090200=PMID:20436456, GO:0006338=PMID:10891486, GO:0001666=GO_REF:0000024, GO:0046902=PMID:10891486, GO:0043066=PMID:7954800, GO:0043065=GO_REF:0000002, GO:0031966=PMID:9396766, GO:0046982=PMID:10381623, GO:0072593=PMID:10891486, GO:0071456=PMID:20436456, GO:0035694=PMID:22292033, GO:0006915=PMID:7954800, GO:0006917=PMID:9396766, GO:0043653=PMID:20436456, GO:0097193=GO_REF:0000019, GO:0051020=PMID:20436456, GO:0010637=PMID:20436456, GO:0045837=PMID:10891486, GO:0050873=GO_REF:0000019, GO:0006309=PMID:10891486, GO:0019048=GO_REF:0000037, GO:0055093=GO_REF:0000019, GO:0005654=GO_REF:0000024, GO:0016021=GO_REF:0000002, GO:0031307=PMID:10891486, GO:0071260=PMID:19593445} Q12983 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 protein 20110404 {GO:0005515=IPI, GO:0008219=IDA, GO:0048102=IEA, GO:0070301=IEA, GO:0005741=IDA, GO:0005634=IDA, GO:0005635=IDA, GO:0005740=IEA, GO:0090141=IDA, GO:0051402=ISS, GO:0042803=IDA, GO:0030425=ISS, GO:0042802=IPI, GO:0005739=IDA, GO:0051607=IDA, GO:0005737=ISS, GO:0043243=IDA, GO:0071279=IMP, GO:0090200=IDA, GO:0006338=IDA, GO:0001666=ISS, GO:0046902=IDA, GO:0043066=TAS, GO:0043065=IEA, GO:0031966=IMP, GO:0046982=IDA, GO:0072593=IDA, GO:0071456=IMP, GO:0035694=IMP, GO:0006915=IPI, GO:0006917=IDA, GO:0043653=IDA, GO:0097193=IEA, GO:0051020=IPI, GO:0010637=IDA, GO:0045837=IDA, GO:0050873=IEA, GO:0006309=IDA, GO:0019048=IEA, GO:0055093=IEA, GO:0005654=ISS, GO:0016021=IEA, GO:0031307=IDA, GO:0071260=IEP} apoptotic DNA fragmentation, apoptotic process, autophagic cell death, brown fat cell differentiation, cell death, cellular response to cobalt ion, cellular response to hydrogen peroxide, cellular response to hypoxia, cellular response to mechanical stimulus, chromatin remodeling, defense response to virus, induction of apoptosis, intrinsic apoptotic signaling pathway, mitochondrial fragmentation involved in apoptotic process, mitochondrial protein catabolic process, negative regulation of apoptotic process, negative regulation of membrane potential, negative regulation of mitochondrial fusion, neuron apoptotic process, positive regulation of apoptotic process, positive regulation of mitochondrial fission, positive regulation of protein complex disassembly, positive regulation of release of cytochrome c from mitochondria, reactive oxygen species metabolic process, regulation of mitochondrial membrane permeability, response to hyperoxia, response to hypoxia, virus-host interaction cytoplasm, dendrite, integral to membrane, integral to mitochondrial outer membrane, mitochondrial envelope, mitochondrial membrane, mitochondrial outer membrane, mitochondrion, nuclear envelope, nucleoplasm, nucleus GTPase binding, identical protein binding, protein binding, protein heterodimerization activity, protein homodimerization activity Human UniProtKB:O60313 BNIP3L IntAct UniProtKB {GO:0005515=PMID:22645275, GO:0043066=PMID:10381623, GO:0043065=GO_REF:0000002, GO:0046982=PMID:10381623, GO:0005783=PMID:10381623, GO:0035694=PMID:21264228, GO:0006915=GO_REF:0000037, GO:0005741=PMID:21264228, GO:0031224=PMID:10381623, GO:0006917=PMID:9973195, GO:0005740=GO_REF:0000002, GO:0005635=PMID:10381623, GO:0042803=PMID:10381623, GO:0042802=PMID:16189514, GO:0005739=PMID:9973195, GO:0051607=PMID:9973195, GO:0019048=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005521=PMID:10381623} O60238 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like protein 20130415 {GO:0005515=IPI, GO:0043066=IDA, GO:0043065=IEA, GO:0046982=IDA, GO:0005783=IDA, GO:0035694=IMP, GO:0006915=IEA, GO:0005741=IMP, GO:0031224=TAS, GO:0006917=IDA, GO:0005740=IEA, GO:0005635=IDA, GO:0042803=IDA, GO:0042802=IPI, GO:0005739=IDA, GO:0051607=IDA, GO:0019048=IEA, GO:0016021=IEA, GO:0005521=IDA} apoptotic process, defense response to virus, induction of apoptosis, mitochondrial protein catabolic process, negative regulation of apoptotic process, positive regulation of apoptotic process, virus-host interaction endoplasmic reticulum, integral to membrane, intrinsic to membrane, mitochondrial envelope, mitochondrial outer membrane, mitochondrion, nuclear envelope identical protein binding, lamin binding, protein binding, protein heterodimerization activity, protein homodimerization activity Human UniProtKB:O60238 BNIPL MGI UniProtKB {GO:0005515=PMID:12681488, GO:0008285=PMID:12681488, GO:0006915=PMID:12901880, GO:0005634=PMID:11741952, GO:0006917=PMID:11741952, GO:0040009=PMID:12681488, GO:0042802=PMID:12901880, GO:0005829=PMID:11741952} Q7Z465 Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein protein 20091109 {GO:0005515=IPI, GO:0008285=IDA, GO:0006915=IDA, GO:0005634=IDA, GO:0006917=IDA, GO:0040009=IDA, GO:0042802=IPI, GO:0005829=IDA} apoptotic process, induction of apoptosis, negative regulation of cell proliferation, regulation of growth rate cytosol, nucleus identical protein binding, protein binding Human BOC Reactome UniProtKB {GO:0042692=Reactome:REACT_21303, GO:0005515=PMID:11782431, GO:0051149=Reactome:REACT_21402, GO:0005886=Reactome:REACT_21377, GO:0007411=GO_REF:0000019, GO:0045663=GO_REF:0000024, GO:0043025=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037, GO:0044295=GO_REF:0000019, GO:0007224=GO_REF:0000019} Q9BWV1 Brother of CDO protein 20091030 {GO:0042692=TAS, GO:0005515=IPI, GO:0051149=TAS, GO:0005886=TAS, GO:0007411=IEA, GO:0045663=ISS, GO:0043025=IEA, GO:0016021=IEA, GO:0007155=IEA, GO:0044295=IEA, GO:0007224=IEA} axon guidance, cell adhesion, muscle cell differentiation, positive regulation of muscle cell differentiation, positive regulation of myoblast differentiation, smoothened signaling pathway axonal growth cone, integral to membrane, neuronal cell body, plasma membrane protein binding Human BOD1 UniProtKB UniProtKB {GO:0007067=GO_REF:0000037, GO:0005737=GO_REF:0000037, GO:0005815=GO_REF:0000039, GO:0000777=GO_REF:0000039, GO:0051301=GO_REF:0000037} Q96IK1 Biorientation of chromosomes in cell division protein 1 protein 20130413 {GO:0007067=IEA, GO:0005737=IEA, GO:0005815=IEA, GO:0000777=IEA, GO:0051301=IEA} cell division, mitosis condensed chromosome kinetochore, cytoplasm, microtubule organizing center Human UniProtKB-SubCell:SL-0048 BOK UniProtKB UniProtKB {GO:0005515=PMID:15868100, GO:0051400=GO_REF:0000019, GO:0031966=PMID:15868100, GO:0046982=GO_REF:0000019, GO:0008283=PMID:19095301, GO:0048709=GO_REF:0000019, GO:0006919=PMID:20673843, GO:0006915=PMID:15102863, GO:0005634=PMID:19095301, GO:0006917=PMID:20673843, GO:0005739=PMID:19095301, GO:0005737=PMID:20673843, GO:0072332=PMID:15102863, GO:0007420=GO_REF:0000019, GO:0008584=GO_REF:0000019} Q9UMX3 Bcl-2-related ovarian killer protein protein 20110328 {GO:0005515=IPI, GO:0051400=IEA, GO:0031966=IDA, GO:0046982=IEA, GO:0008283=IEP, GO:0048709=IEA, GO:0006919=IMP, GO:0006915=IDA, GO:0005634=IDA, GO:0006917=IMP, GO:0005739=IDA, GO:0005737=IDA, GO:0072332=IMP, GO:0007420=IEA, GO:0008584=IEA} activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, brain development, cell proliferation, induction of apoptosis, intrinsic apoptotic signaling pathway by p53 class mediator, male gonad development, oligodendrocyte differentiation cytoplasm, mitochondrial membrane, mitochondrion, nucleus BH domain binding, protein binding, protein heterodimerization activity Human BOLA1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0005576=GO_REF:0000039} Q9Y3E2 BolA-like protein 1 protein 20130413 {GO:0005739=IEA, GO:0005576=IEA} extracellular region, mitochondrion Human UniProtKB-SubCell:SL-0243 BOLA2 null null {} null null null null {} null null null BOLA2B null null {} null null null null {} null null null BOLL MGI UniProtKB {GO:0005515=PMID:16001084, GO:0005737=PMID:11390979, GO:0007126=PMID:12499397, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0045948=PMID:16001084, GO:0008494=PMID:16001084, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0030154=GO_REF:0000037} Q8N9W6 Protein boule-like protein 20060110 {GO:0005515=IPI, GO:0005737=IDA, GO:0007126=IDA, GO:0000166=IEA, GO:0003723=IEA, GO:0045948=IDA, GO:0008494=IDA, GO:0007275=IEA, GO:0007283=IEA, GO:0003676=IEA, GO:0030154=IEA} cell differentiation, meiosis, multicellular organismal development, positive regulation of translational initiation, spermatogenesis cytoplasm RNA binding, nucleic acid binding, nucleotide binding, protein binding, translation activator activity Human BOP1 IntAct UniProtKB {GO:0005515=PMID:16043514, GO:0070545=PMID:16738141, GO:0000463=PMID:17353269, GO:0008283=PMID:16043514, GO:0030529=PMID:18809582, GO:0042254=PMID:16043514, GO:0006364=GO_REF:0000002, GO:0051726=PMID:16043514, GO:0005654=GO_REF:0000039} Q14137 Ribosome biogenesis protein BOP1 protein 20130415 {GO:0005515=IPI, GO:0070545=IDA, GO:0000463=IMP, GO:0008283=NAS, GO:0030529=IDA, GO:0042254=NAS, GO:0006364=IEA, GO:0051726=IMP, GO:0005654=IEA} cell proliferation, maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), rRNA processing, regulation of cell cycle, ribosome biogenesis PeBoW complex, nucleoplasm, ribonucleoprotein complex protein binding Human UniProtKB:Q9GZL7 BORA UniProtKB UniProtKB {GO:0032880=PMID:18521620, GO:0005515=PMID:18521620, GO:0007088=PMID:18521620, GO:0007067=GO_REF:0000037, GO:0019901=PMID:18615013, GO:0060236=PMID:18521620, GO:0051301=GO_REF:0000037} Q6PGQ7 Protein aurora borealis protein 20100301 {GO:0032880=IMP, GO:0005515=IPI, GO:0007088=IMP, GO:0007067=IEA, GO:0019901=IPI, GO:0060236=IMP, GO:0051301=IEA} cell division, mitosis, regulation of mitosis, regulation of mitotic spindle organization, regulation of protein localization protein binding, protein kinase binding Human UniProtKB:P53350 BPGM PINC UniProtKB {GO:0007585=PMID:2542247, GO:0004082=GO_REF:0000003, GO:0005975=PMID:2542247, GO:0004083=GO_REF:0000003, GO:0004619=GO_REF:0000003, GO:0006096=GO_REF:0000037} P07738 Bisphosphoglycerate mutase protein 20030904 {GO:0007585=TAS, GO:0004082=IEA, GO:0005975=NAS, GO:0004083=IEA, GO:0004619=IEA, GO:0006096=IEA} carbohydrate metabolic process, glycolysis, respiratory gaseous exchange bisphosphoglycerate 2-phosphatase activity, bisphosphoglycerate mutase activity, phosphoglycerate mutase activity Human BPHL PINC UniProtKB {GO:0005739=GO_REF:0000024, GO:0006520=PMID:7759552, GO:0016787=GO_REF:0000037, GO:0009636=PMID:7759552} Q86WA6 Valacyclovir hydrolase protein 20050308 {GO:0005739=ISS, GO:0006520=TAS, GO:0016787=IEA, GO:0009636=TAS} cellular amino acid metabolic process, response to toxic substance mitochondrion hydrolase activity Human BPI BHF-UCL UniProtKB {GO:0001530=PMID:8409400, GO:0051636=GO_REF:0000019, GO:0006955=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0032717=PMID:8409400, GO:0032715=PMID:8409400, GO:0005887=PMID:2722846, GO:0043031=PMID:8409400, GO:0032720=PMID:8409400, GO:0005576=GO_REF:0000039, GO:0042742=GO_REF:0000019, GO:0008289=GO_REF:0000002} P17213 Bactericidal permeability-increasing protein protein 20080707 {GO:0001530=IDA, GO:0051636=IEA, GO:0006955=IEA, GO:0005737=IEA, GO:0032717=IDA, GO:0032715=IDA, GO:0005887=TAS, GO:0043031=IDA, GO:0032720=IDA, GO:0005576=IEA, GO:0042742=IEA, GO:0008289=IEA} defense response to bacterium, immune response, negative regulation of interleukin-6 production, negative regulation of interleukin-8 production, negative regulation of macrophage activation, negative regulation of tumor necrosis factor production cytoplasm, extracellular region, integral to plasma membrane Gram-negative bacterial cell surface binding, lipid binding, lipopolysaccharide binding Human BPIFA1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0045087=PMID:11971875, GO:0005576=PMID:11425234, GO:0008289=GO_REF:0000002} Q9NP55 BPI fold-containing family A member 1 protein 20061026 {GO:0003674=ND, GO:0045087=NAS, GO:0005576=IDA, GO:0008289=IEA} innate immune response extracellular region lipid binding, molecular_function Human BPIFB1 InterPro UniProtKB {GO:0005615=GO_REF:0000002, GO:0008289=GO_REF:0000002} Q8TDL5 BPI fold-containing family B member 1 protein 20130413 {GO:0005615=IEA, GO:0008289=IEA} extracellular space lipid binding Human InterPro:IPR001124|InterPro:IPR017942|InterPro:IPR017943 BPIFB3 UniProtKB UniProtKB {GO:0005737=PMID:12837268, GO:0045087=PMID:11971875, GO:0005576=GO_REF:0000039, GO:0008289=GO_REF:0000002} P59826 BPI fold-containing family B member 3 protein 20051025 {GO:0005737=IDA, GO:0045087=NAS, GO:0005576=IEA, GO:0008289=IEA} innate immune response cytoplasm, extracellular region lipid binding Human BPNT1 Reactome UniProtKB {GO:0046854=GO_REF:0000002, GO:0006139=PMID:10224133, GO:0006805=Reactome:REACT_13433, GO:0008441=GO_REF:0000003, GO:0000287=GO_REF:0000019, GO:0050427=Reactome:REACT_6913, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_6763, GO:0007399=PMID:10224133, GO:0004441=GO_REF:0000019} O95861 3'(2'),5'-bisphosphate nucleotidase 1 protein 20130301 {GO:0046854=IEA, GO:0006139=TAS, GO:0006805=TAS, GO:0008441=IEA, GO:0000287=IEA, GO:0050427=TAS, GO:0044281=TAS, GO:0005829=TAS, GO:0007399=TAS, GO:0004441=IEA} 3'-phosphoadenosine 5'-phosphosulfate metabolic process, nervous system development, nucleobase-containing compound metabolic process, phosphatidylinositol phosphorylation, small molecule metabolic process, xenobiotic metabolic process cytosol 3'(2'),5'-bisphosphate nucleotidase activity, inositol-1,4-bisphosphate 1-phosphatase activity, magnesium ion binding Human BPTF HPA UniProtKB {GO:0005515=PMID:21596426, GO:0006355=PMID:10575013, GO:0005730=GO_REF:0000052, GO:0001892=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0000122=PMID:10727212, GO:0009952=GO_REF:0000019, GO:0006351=PMID:14609955, GO:0043565=PMID:10575013, GO:0005737=GO_REF:0000039, GO:0007492=GO_REF:0000019, GO:0007420=PMID:14609955, GO:0008270=GO_REF:0000002, GO:0006338=PMID:14609955, GO:0045893=PMID:14609955, GO:0016589=PMID:20850016, GO:0008134=PMID:10727212, GO:0008094=PMID:14609955} Q12830 Nucleosome-remodeling factor subunit BPTF protein 20101115 {GO:0005515=IPI, GO:0006355=IMP, GO:0005730=IDA, GO:0001892=IEA, GO:0005634=IDA, GO:0000122=IDA, GO:0009952=IEA, GO:0006351=IMP, GO:0043565=IMP, GO:0005737=IEA, GO:0007492=IEA, GO:0007420=IMP, GO:0008270=IEA, GO:0006338=IDA, GO:0045893=IMP, GO:0016589=IDA, GO:0008134=IDA, GO:0008094=IDA} anterior/posterior pattern specification, brain development, chromatin remodeling, embryonic placenta development, endoderm development, negative regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent NURF complex, cytoplasm, nucleolus, nucleus DNA-dependent ATPase activity, protein binding, sequence-specific DNA binding, transcription factor binding, zinc ion binding NOT Human BPY2 IntAct UniProtKB {GO:0005515=PMID:14627543, GO:0007338=PMID:9381176, GO:0032399=PMID:12207887, GO:0005634=PMID:12724276, GO:0007283=PMID:12724276} O14599 Testis-specific basic protein Y 2 protein 20130415 {GO:0005515=IPI, GO:0007338=TAS, GO:0032399=IPI, GO:0005634=IDA, GO:0007283=IMP} single fertilization, spermatogenesis nucleus HECT domain binding, protein binding Human UniProtKB:Q66K74 BPY2B null null {} null null null null {} null null null BPY2C null null {} null null null null {} null null null BRAF BHF-UCL UniProtKB {GO:0005515=PMID:17563371, GO:0048011=Reactome:REACT_11061, GO:0043066=PMID:19667065, GO:0005886=Reactome:REACT_20578, GO:0007264=Reactome:REACT_12077, GO:0005509=PMID:18567582, GO:0007268=Reactome:REACT_13685, GO:0005634=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_111121, GO:0010628=PMID:22065586, GO:0033138=PMID:19667065, GO:0000186=Reactome:REACT_12005, GO:0004672=PMID:17563371, GO:0008543=Reactome:REACT_9470, GO:0004674=PMID:19667065, GO:0009887=PMID:9207797, GO:0006468=PMID:17563371, GO:0070374=PMID:22065586, GO:0005057=GO_REF:0000002} P15056 Serine/threonine-protein kinase B-raf protein 20120621 {GO:0005515=IPI, GO:0048011=TAS, GO:0043066=IDA, GO:0005886=TAS, GO:0007264=TAS, GO:0005509=IDA, GO:0007268=TAS, GO:0005634=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0010628=IMP, GO:0033138=IDA, GO:0000186=TAS, GO:0004672=IDA, GO:0008543=TAS, GO:0004674=IDA, GO:0009887=TAS, GO:0006468=IDA, GO:0070374=IDA, GO:0005057=IEA} activation of MAPKK activity, fibroblast growth factor receptor signaling pathway, negative regulation of apoptotic process, neurotrophin TRK receptor signaling pathway, organ morphogenesis, positive regulation of ERK1 and ERK2 cascade, positive regulation of gene expression, positive regulation of peptidyl-serine phosphorylation, protein phosphorylation, small GTPase mediated signal transduction, synaptic transmission cytosol, nucleus, plasma membrane ATP binding, calcium ion binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, receptor signaling protein activity Human BRAP IntAct UniProtKB {GO:0005515=PMID:14724641, GO:0005737=PMID:9497340, GO:0004842=PMID:14724641, GO:0000166=GO_REF:0000002, GO:0000165=PMID:14724641, GO:0000151=PMID:14724641, GO:0008139=PMID:9497340, GO:0007265=PMID:14724641, GO:0008270=GO_REF:0000002, GO:0009968=PMID:14724641} Q7Z569 BRCA1-associated protein protein 20130415 {GO:0005515=IPI, GO:0005737=IDA, GO:0004842=IDA, GO:0000166=IEA, GO:0000165=IDA, GO:0000151=IDA, GO:0008139=IDA, GO:0007265=IDA, GO:0008270=IEA, GO:0009968=IDA} MAPK cascade, Ras protein signal transduction, negative regulation of signal transduction cytoplasm, ubiquitin ligase complex nuclear localization sequence binding, nucleotide binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:P01112 BRAT1 UniProtKB UniProtKB {GO:0005515=PMID:16452482, GO:0010212=PMID:16452482, GO:0005634=PMID:16452482} Q6PJG6 BRCA1-associated ATM activator 1 protein 20100510 {GO:0005515=IPI, GO:0010212=IMP, GO:0005634=IDA} response to ionizing radiation nucleus protein binding Human UniProtKB:P38398 BRCA1 ENSEMBL UniProtKB {GO:0005515=PMID:21282464, GO:0004842=PMID:17349954, GO:0043627=PMID:8895509, GO:0044212=GO_REF:0000019, GO:2000145=PMID:21282464, GO:0009048=GO_REF:0000019, GO:0050681=PMID:15572661, GO:0071158=PMID:21102443, GO:2000617=GO_REF:0000019, GO:0070531=PMID:19261749, GO:0042127=PMID:10918303, GO:0044030=GO_REF:0000019, GO:0031398=PMID:15965487, GO:0034446=PMID:21282464, GO:0006978=PMID:10918303, GO:0031625=PMID:17873885, GO:0085020=PMID:12890688, GO:0005694=GO_REF:0000024, GO:0003713=PMID:15572661, GO:0031436=PMID:19117993, GO:0046600=PMID:12214252, GO:0051865=PMID:12890688, GO:0043234=PMID:9774970, GO:0006281=GO_REF:0000002, GO:0005654=Reactome:REACT_21405, GO:0008270=GO_REF:0000002, GO:2000620=GO_REF:0000019, GO:0045893=PMID:15572661, GO:0019899=PMID:15965487, GO:0005925=PMID:21282464, GO:0045892=PMID:16288014, GO:0008274=PMID:12214252, GO:0016567=PMID:17349954, GO:0005886=PMID:21282464, GO:0007098=GO_REF:0000019, GO:0003723=PMID:12419249, GO:0031572=PMID:19261748, GO:0000151=PMID:14976165, GO:0005634=PMID:17643121, GO:0045739=PMID:19261748, GO:0035067=GO_REF:0000019, GO:0035066=PMID:20820192, GO:0043009=GO_REF:0000019, GO:0006301=PMID:17349954, GO:0006302=Reactome:REACT_2054, GO:0071681=PMID:10868478, GO:0005737=GO_REF:0000019, GO:0007059=PMID:15965487, GO:0015631=PMID:12214252, GO:0000724=Reactome:REACT_1874, GO:0045944=GO_REF:0000019, GO:0010212=PMID:19261748, GO:0070512=GO_REF:0000019, GO:0006633=GO_REF:0000037, GO:0000794=GO_REF:0000019, GO:0008630=PMID:14654789, GO:0006357=PMID:10910365, GO:0006359=PMID:10918303, GO:0045717=PMID:16326698, GO:0006915=PMID:10918303, GO:0042981=PMID:10918303, GO:0001726=PMID:21282464, GO:0003677=PMID:9662397, GO:0006974=PMID:10910365, GO:0003684=GO_REF:0000019, GO:0006260=GO_REF:0000019, GO:0051574=GO_REF:0000019, GO:0031941=PMID:21282464, GO:0051571=GO_REF:0000019, GO:0030529=PMID:18809582, GO:0051573=GO_REF:0000019, GO:0051572=GO_REF:0000019, GO:0006349=GO_REF:0000019, GO:0030521=PMID:15572661} Q3B891 Breast cancer type 1 susceptibility protein protein 20130413 {GO:0005515=IPI, GO:0004842=IDA, GO:0043627=IDA, GO:0044212=IEA, GO:2000145=IDA, GO:0009048=IEA, GO:0050681=NAS, GO:0071158=IDA, GO:2000617=IEA, GO:0070531=IDA, GO:0042127=TAS, GO:0044030=IEA, GO:0031398=IDA, GO:0034446=IDA, GO:0006978=TAS, GO:0031625=IPI, GO:0085020=IDA, GO:0005694=ISS, GO:0003713=NAS, GO:0031436=IDA, GO:0046600=NAS, GO:0051865=IDA, GO:0043234=IDA, GO:0006281=IEA, GO:0005654=TAS, GO:0008270=IEA, GO:2000620=IEA, GO:0045893=NAS, GO:0019899=IPI, GO:0005925=IDA, GO:0045892=IDA, GO:0008274=NAS, GO:0016567=IDA, GO:0005886=IDA, GO:0007098=IEA, GO:0003723=IDA, GO:0031572=IMP, GO:0000151=NAS, GO:0005634=IDA, GO:0045739=IMP, GO:0035067=IEA, GO:0035066=IDA, GO:0043009=IEA, GO:0006301=IDA, GO:0006302=TAS, GO:0071681=IDA, GO:0005737=IEA, GO:0007059=IMP, GO:0015631=NAS, GO:0000724=TAS, GO:0045944=IEA, GO:0010212=IMP, GO:0070512=IEA, GO:0006633=IEA, GO:0000794=IEA, GO:0008630=IDA, GO:0006357=TAS, GO:0006359=TAS, GO:0045717=IMP, GO:0006915=TAS, GO:0042981=TAS, GO:0001726=IDA, GO:0003677=TAS, GO:0006974=TAS, GO:0003684=IEA, GO:0006260=IEA, GO:0051574=IEA, GO:0031941=IDA, GO:0051571=IEA, GO:0030529=IDA, GO:0051573=IEA, GO:0051572=IEA, GO:0006349=IEA, GO:0030521=NAS} DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, DNA repair, DNA replication, G2 DNA damage checkpoint, androgen receptor signaling pathway, apoptotic process, cellular response to indole-3-methanol, centrosome cycle, chordate embryonic development, chromosome segregation, dosage compensation by inactivation of X chromosome, double-strand break repair, double-strand break repair via homologous recombination, fatty acid biosynthetic process, intrinsic apoptotic signaling pathway in response to DNA damage, negative regulation of centriole replication, negative regulation of fatty acid biosynthetic process, negative regulation of histone H3-K4 methylation, negative regulation of histone H3-K9 methylation, negative regulation of histone acetylation, negative regulation of transcription, DNA-dependent, positive regulation of DNA repair, positive regulation of cell cycle arrest, positive regulation of histone H3-K4 methylation, positive regulation of histone H3-K9 acetylation, positive regulation of histone H3-K9 methylation, positive regulation of histone H4-K16 acetylation, positive regulation of histone H4-K20 methylation, positive regulation of histone acetylation, positive regulation of protein ubiquitination, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, postreplication repair, protein K6-linked ubiquitination, protein autoubiquitination, protein ubiquitination, regulation of DNA methylation, regulation of apoptotic process, regulation of cell motility, regulation of cell proliferation, regulation of gene expression by genetic imprinting, regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase III promoter, response to DNA damage stimulus, response to estrogen stimulus, response to ionizing radiation, substrate adhesion-dependent cell spreading BRCA1-A complex, BRCA1-BARD1 complex, chromosome, condensed nuclear chromosome, cytoplasm, filamentous actin, focal adhesion, gamma-tubulin ring complex, nucleoplasm, nucleus, plasma membrane, protein complex, ribonucleoprotein complex, ruffle, ubiquitin ligase complex DNA binding, RNA binding, androgen receptor binding, damaged DNA binding, enzyme binding, protein binding, transcription coactivator activity, transcription regulatory region DNA binding, tubulin binding, ubiquitin protein ligase binding, ubiquitin-protein ligase activity, zinc ion binding Human Ensembl:ENSMUSP00000017290 BRCA2 HPA UniProtKB {GO:0005515=PMID:21399666, GO:0010165=GO_REF:0000019, GO:0048478=GO_REF:0000019, GO:0001833=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0007283=GO_REF:0000019, GO:0001556=GO_REF:0000019, GO:0002020=PMID:15314155, GO:0033593=PMID:15930293, GO:0006302=Reactome:REACT_2054, GO:0005737=GO_REF:0000052, GO:0003697=PMID:20729832, GO:0000724=Reactome:REACT_1874, GO:0010485=PMID:9619837, GO:0006978=GO_REF:0000019, GO:0007090=GO_REF:0000002, GO:0030141=PMID:8589722, GO:0010332=GO_REF:0000019, GO:0004402=PMID:9824164, GO:0030097=GO_REF:0000019, GO:0005813=PMID:17286961, GO:0032465=GO_REF:0000019, GO:0043015=PMID:17286961, GO:0010484=PMID:9619837, GO:0007569=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0008585=GO_REF:0000019, GO:0042771=GO_REF:0000019, GO:0051298=PMID:17286961, GO:0043234=PMID:9774970, GO:0010225=GO_REF:0000019, GO:0045931=GO_REF:0000019, GO:0006281=Reactome:REACT_216, GO:0043966=PMID:9619837, GO:0043967=PMID:9619837, GO:0007420=GO_REF:0000019, GO:0005654=Reactome:REACT_1612, GO:0006289=PMID:16845393, GO:0045893=PMID:9126734, GO:0033600=PMID:15930293, GO:0007141=GO_REF:0000019} P51587 Breast cancer type 2 susceptibility protein protein 20101115 {GO:0005515=IPI, GO:0010165=IEA, GO:0048478=IEA, GO:0001833=IEA, GO:0005634=IDA, GO:0007283=IEA, GO:0001556=IEA, GO:0002020=IPI, GO:0033593=IDA, GO:0006302=TAS, GO:0005737=IDA, GO:0003697=IDA, GO:0000724=TAS, GO:0010485=IDA, GO:0006978=IEA, GO:0007090=IEA, GO:0030141=IDA, GO:0010332=IEA, GO:0004402=IDA, GO:0030097=IEA, GO:0005813=IDA, GO:0032465=IEA, GO:0043015=IPI, GO:0010484=IDA, GO:0007569=IEA, GO:0005730=IDA, GO:0008585=IEA, GO:0042771=IEA, GO:0051298=IMP, GO:0043234=IDA, GO:0010225=IEA, GO:0045931=IEA, GO:0006281=TAS, GO:0043966=IDA, GO:0043967=IDA, GO:0007420=IEA, GO:0005654=TAS, GO:0006289=IMP, GO:0045893=IDA, GO:0033600=IDA, GO:0007141=IEA} DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, DNA repair, brain development, cell aging, centrosome duplication, double-strand break repair, double-strand break repair via homologous recombination, female gonad development, hemopoiesis, histone H3 acetylation, histone H4 acetylation, inner cell mass cell proliferation, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, male meiosis I, negative regulation of mammary gland epithelial cell proliferation, nucleotide-excision repair, oocyte maturation, positive regulation of mitotic cell cycle, positive regulation of transcription, DNA-dependent, regulation of S phase of mitotic cell cycle, regulation of cytokinesis, replication fork protection, response to UV-C, response to X-ray, response to gamma radiation, spermatogenesis BRCA2-MAGE-D1 complex, centrosome, cytoplasm, nucleolus, nucleoplasm, nucleus, protein complex, secretory granule H3 histone acetyltransferase activity, H4 histone acetyltransferase activity, gamma-tubulin binding, histone acetyltransferase activity, protease binding, protein binding, single-stranded DNA binding Human BRCC3 GOC UniProtKB {GO:0005515=PMID:14636569, GO:0004843=PMID:19261746, GO:0010165=PMID:14636569, GO:0031572=PMID:17525341, GO:0000151=PMID:14636569, GO:0005634=PMID:19202061, GO:0045739=PMID:19261746, GO:0000152=PMID:14636569, GO:0046872=GO_REF:0000037, GO:0006302=PMID:19261748, GO:0070531=PMID:19261746, GO:0050790=PMID:14636569, GO:0070552=PMID:19214193, GO:0070536=PMID:17525341, GO:0010212=PMID:19261746, GO:0070537=PMID:19202061, GO:0006508=GO_REF:0000037, GO:0030234=PMID:14636569, GO:0004221=PMID:19214193, GO:0008237=PMID:19261746, GO:0031593=PMID:19261749} P46736 Lys-63-specific deubiquitinase BRCC36 protein 20130413 {GO:0005515=IPI, GO:0004843=IMP, GO:0010165=IDA, GO:0031572=IMP, GO:0000151=IDA, GO:0005634=IDA, GO:0045739=IMP, GO:0000152=IDA, GO:0046872=IEA, GO:0006302=IMP, GO:0070531=IDA, GO:0050790=IDA, GO:0070552=IDA, GO:0070536=IDA, GO:0010212=IMP, GO:0070537=IDA, GO:0006508=IEA, GO:0030234=IDA, GO:0004221=IMP, GO:0008237=IMP, GO:0031593=IDA} G2 DNA damage checkpoint, double-strand break repair, histone H2A K63-linked deubiquitination, positive regulation of DNA repair, protein K63-linked deubiquitination, proteolysis, regulation of catalytic activity, response to X-ray, response to ionizing radiation BRCA1-A complex, BRISC complex, nuclear ubiquitin ligase complex, nucleus, ubiquitin ligase complex enzyme regulator activity, metal ion binding, metallopeptidase activity, polyubiquitin binding, protein binding, ubiquitin thiolesterase activity, ubiquitin-specific protease activity Human BRD1 HPA UniProtKB {GO:0042393=PMID:21880731, GO:0070776=PMID:16387653, GO:0043966=PMID:16387653, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002} O95696 Bromodomain-containing protein 1 protein 20080205 {GO:0042393=IDA, GO:0070776=IDA, GO:0043966=IDA, GO:0005634=IDA, GO:0008270=IEA} histone H3 acetylation MOZ/MORF histone acetyltransferase complex, nucleus histone binding, zinc ion binding Human BRD2 PINC UniProtKB {GO:0005737=GO_REF:0000019, GO:0006357=PMID:18406326, GO:0003682=PMID:18406326, GO:0006334=PMID:18406326, GO:0070577=PMID:18406326, GO:0005634=GO_REF:0000039, GO:0007283=PMID:9693039, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} P25440 Bromodomain-containing protein 2 protein 20030904 {GO:0005737=IEA, GO:0006357=IDA, GO:0003682=IDA, GO:0006334=IMP, GO:0070577=IDA, GO:0005634=IEA, GO:0007283=TAS, GO:0006351=IEA, GO:0016568=IEA} chromatin modification, nucleosome assembly, regulation of transcription from RNA polymerase II promoter, spermatogenesis, transcription, DNA-dependent cytoplasm, nucleus chromatin binding, histone acetyl-lysine binding Human BRD3 IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0006357=PMID:18406326, GO:0003682=PMID:18406326, GO:0070577=PMID:22464331, GO:0005634=GO_REF:0000029, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q15059 Bromodomain-containing protein 3 protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0003674=ND, GO:0006357=IDA, GO:0003682=IDA, GO:0070577=IDA, GO:0005634=NAS, GO:0006351=IEA, GO:0016568=IEA} biological_process, chromatin modification, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus chromatin binding, histone acetyl-lysine binding, molecular_function, protein binding Human UniProtKB:P01106 BRD4 HPA UniProtKB {GO:0005515=PMID:17474147, GO:0000790=GO_REF:0000019, GO:0000794=PMID:10938129, GO:0001833=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0043983=GO_REF:0000019, GO:0010971=PMID:10938129, GO:0007059=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0043388=GO_REF:0000019, GO:0000114=PMID:18039861, GO:0032968=PMID:18039861, GO:0006468=GO_REF:0000019, GO:0044154=GO_REF:0000019} O60885 Bromodomain-containing protein 4 protein 20090616 {GO:0005515=IPI, GO:0000790=IEA, GO:0000794=IDA, GO:0001833=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0005737=IDA, GO:0043983=IEA, GO:0010971=IMP, GO:0007059=IEA, GO:0019048=IEA, GO:0043388=IEA, GO:0000114=IMP, GO:0032968=IMP, GO:0006468=IEA, GO:0044154=IEA} chromosome segregation, histone H3-K14 acetylation, histone H4-K12 acetylation, inner cell mass cell proliferation, positive regulation of DNA binding, positive regulation of G2/M transition of mitotic cell cycle, positive regulation of transcription elongation from RNA polymerase II promoter, protein phosphorylation, regulation of transcription involved in G1 phase of mitotic cell cycle, virus-host interaction condensed nuclear chromosome, cytoplasm, nuclear chromatin, nucleolus, nucleus DNA binding, protein binding Human BRD7 IntAct UniProtKB {GO:0005515=PMID:20228809, GO:0008285=PMID:20228809, GO:0006357=PMID:12489984, GO:0044212=PMID:20228809, GO:0003714=PMID:16265664, GO:0003713=PMID:20228809, GO:2000134=PMID:16265664, GO:0005634=PMID:12489984, GO:0035066=PMID:20228809, GO:0006351=GO_REF:0000037, GO:0042393=PMID:12489984, GO:0002039=PMID:20228809, GO:0005737=PMID:10526152, GO:0007049=GO_REF:0000037, GO:0070577=PMID:16265664, GO:0016055=GO_REF:0000037, GO:0045893=PMID:20228809, GO:0045892=PMID:16265664, GO:0008134=PMID:11025449} Q9NPI1 Bromodomain-containing protein 7 protein 20130415 {GO:0005515=IPI, GO:0008285=IDA, GO:0006357=IDA, GO:0044212=IDA, GO:0003714=IDA, GO:0003713=IDA, GO:2000134=IDA, GO:0005634=IDA, GO:0035066=IDA, GO:0006351=IEA, GO:0042393=IDA, GO:0002039=IPI, GO:0005737=TAS, GO:0007049=IEA, GO:0070577=IDA, GO:0016055=IEA, GO:0045893=IDA, GO:0045892=IDA, GO:0008134=IDA} Wnt receptor signaling pathway, cell cycle, negative regulation of G1/S transition of mitotic cell cycle, negative regulation of cell proliferation, negative regulation of transcription, DNA-dependent, positive regulation of histone acetylation, positive regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, nucleus histone acetyl-lysine binding, histone binding, p53 binding, protein binding, transcription coactivator activity, transcription corepressor activity, transcription factor binding, transcription regulatory region DNA binding Human UniProtKB:Q09472 BRD8 HPA UniProtKB {GO:0006355=PMID:8611617, GO:0003700=PMID:8611617, GO:0006357=PMID:9368056, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005739=GO_REF:0000052, GO:0007165=PMID:9368056, GO:0043967=PMID:14966270, GO:0043968=PMID:14966270, GO:0035267=PMID:14966270, GO:0004887=PMID:9368056, GO:0040008=GO_REF:0000037, GO:0007166=PMID:9368056} Q9H0E9 Bromodomain-containing protein 8 protein 20080818 {GO:0006355=NAS, GO:0003700=NAS, GO:0006357=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0005739=IDA, GO:0007165=TAS, GO:0043967=IDA, GO:0043968=IDA, GO:0035267=IDA, GO:0004887=TAS, GO:0040008=IEA, GO:0007166=TAS} cell surface receptor signaling pathway, histone H2A acetylation, histone H4 acetylation, regulation of growth, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, signal transduction NuA4 histone acetyltransferase complex, mitochondrion, nucleolus, nucleus sequence-specific DNA binding transcription factor activity, thyroid hormone receptor activity Human BRD9 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0006355=GO_REF:0000037, GO:0070577=PMID:22464331, GO:0005575=GO_REF:0000015, GO:0003676=PMID:18559093, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q9H8M2 Bromodomain-containing protein 9 protein 20120706 {GO:0008150=ND, GO:0006355=IEA, GO:0070577=IDA, GO:0005575=ND, GO:0003676=NAS, GO:0006351=IEA, GO:0016568=IEA} biological_process, chromatin modification, regulation of transcription, DNA-dependent, transcription, DNA-dependent cellular_component histone acetyl-lysine binding, nucleic acid binding Human BRDT UniProtKB UniProtKB {GO:0006397=GO_REF:0000037, GO:0008380=GO_REF:0000037, GO:0003713=PMID:10365964, GO:0005634=GO_REF:0000024, GO:0001207=GO_REF:0000024, GO:0007283=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0042393=PMID:22464331, GO:0051039=GO_REF:0000024, GO:0070577=GO_REF:0000024, GO:0006338=GO_REF:0000024, GO:0043484=GO_REF:0000024, GO:0007141=GO_REF:0000024, GO:0007140=GO_REF:0000024} Q58F21 Bromodomain testis-specific protein protein 20121022 {GO:0006397=IEA, GO:0008380=IEA, GO:0003713=TAS, GO:0005634=ISS, GO:0001207=ISS, GO:0007283=ISS, GO:0006351=IEA, GO:0030154=IEA, GO:0042393=IDA, GO:0051039=ISS, GO:0070577=ISS, GO:0006338=ISS, GO:0043484=ISS, GO:0007141=ISS, GO:0007140=ISS} RNA splicing, cell differentiation, chromatin remodeling, histone displacement, mRNA processing, male meiosis, male meiosis I, positive regulation of transcription during meiosis, regulation of RNA splicing, spermatogenesis, transcription, DNA-dependent nucleus histone acetyl-lysine binding, histone binding, transcription coactivator activity Human UniProtKB:Q91Y44 BRE HPA UniProtKB {GO:0005515=PMID:19615732, GO:0005164=PMID:15465831, GO:0000268=PMID:11676476, GO:0031572=PMID:19261748, GO:0006915=GO_REF:0000037, GO:0005634=PMID:15465831, GO:0045739=PMID:19261748, GO:0000152=PMID:14636569, GO:0006974=PMID:7826398, GO:0006302=PMID:19261748, GO:0007165=PMID:9737713, GO:0070531=PMID:19261746, GO:0005737=GO_REF:0000052, GO:0070552=PMID:19214193, GO:0010212=PMID:19261749, GO:0016568=GO_REF:0000037, GO:0031593=PMID:19261749} Q9NXR7 BRCA1-A complex subunit BRE protein 20100326 {GO:0005515=IPI, GO:0005164=IDA, GO:0000268=TAS, GO:0031572=IMP, GO:0006915=IEA, GO:0005634=IDA, GO:0045739=IMP, GO:0000152=IDA, GO:0006974=IEP, GO:0006302=IMP, GO:0007165=TAS, GO:0070531=IDA, GO:0005737=IDA, GO:0070552=IDA, GO:0010212=IMP, GO:0016568=IEA, GO:0031593=IDA} G2 DNA damage checkpoint, apoptotic process, chromatin modification, double-strand break repair, positive regulation of DNA repair, response to DNA damage stimulus, response to ionizing radiation, signal transduction BRCA1-A complex, BRISC complex, cytoplasm, nuclear ubiquitin ligase complex, nucleus peroxisome targeting sequence binding, polyubiquitin binding, protein binding, tumor necrosis factor receptor binding Human BRF1 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0006352=GO_REF:0000002, GO:0043488=GO_REF:0000019, GO:0009304=PMID:8943358, GO:0006355=GO_REF:0000002, GO:0009303=PMID:7624363, GO:0005634=GO_REF:0000002, GO:0006384=PMID:7624363, GO:0006383=Reactome:REACT_1371, GO:0000126=PMID:8943358, GO:0017025=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_1779, GO:0045893=GO_REF:0000002} Q92994 Transcription factor IIIB 90 kDa subunit protein 20130213 {GO:0010467=TAS, GO:0006352=IEA, GO:0043488=IEA, GO:0009304=TAS, GO:0006355=IEA, GO:0009303=TAS, GO:0005634=IEA, GO:0006384=TAS, GO:0006383=TAS, GO:0000126=NAS, GO:0017025=IEA, GO:0008270=IEA, GO:0005654=TAS, GO:0045893=IEA} DNA-dependent transcription, initiation, gene expression, positive regulation of transcription, DNA-dependent, rRNA transcription, regulation of mRNA stability, regulation of transcription, DNA-dependent, tRNA transcription, transcription from RNA polymerase III promoter, transcription initiation from RNA polymerase III promoter nucleoplasm, nucleus, transcription factor TFIIIB complex TBP-class protein binding, zinc ion binding Human BRF2 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0006352=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005654=Reactome:REACT_328, GO:0008270=GO_REF:0000002, GO:0006383=Reactome:REACT_1371} Q9HAW0 Transcription factor IIIB 50 kDa subunit protein 20130213 {GO:0010467=TAS, GO:0006352=IEA, GO:0006355=IEA, GO:0005654=TAS, GO:0008270=IEA, GO:0006383=TAS} DNA-dependent transcription, initiation, gene expression, regulation of transcription, DNA-dependent, transcription from RNA polymerase III promoter nucleoplasm zinc ion binding Human BRI3 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} O95415 Brain protein I3 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 BRI3BP UniProtKB UniProtKB {GO:0005741=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q8WY22 BRI3-binding protein protein 20130413 {GO:0005741=IEA, GO:0016021=IEA} integral to membrane, mitochondrial outer membrane Human UniProtKB-SubCell:SL-0172 BRIP1 HPA UniProtKB {GO:0008026=GO_REF:0000002, GO:0005515=PMID:17525340, GO:0031965=GO_REF:0000052, GO:0016817=GO_REF:0000002, GO:0051539=GO_REF:0000037, GO:0006357=PMID:14504288, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0003677=PMID:15878853, GO:0046872=GO_REF:0000037, GO:0006302=PMID:11301010, GO:0005737=PMID:14504288, GO:0004003=PMID:11301010, GO:0000077=PMID:14576433} Q9BX63 Fanconi anemia group J protein protein 20090616 {GO:0008026=IEA, GO:0005515=IPI, GO:0031965=IDA, GO:0016817=IEA, GO:0051539=IEA, GO:0006357=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0003676=IEA, GO:0005524=IEA, GO:0003677=NAS, GO:0046872=IEA, GO:0006302=NAS, GO:0005737=IDA, GO:0004003=NAS, GO:0000077=NAS} DNA damage checkpoint, double-strand break repair, regulation of transcription from RNA polymerase II promoter, small molecule metabolic process cytoplasm, nuclear membrane, nucleus 4 iron, 4 sulfur cluster binding, ATP binding, ATP-dependent DNA helicase activity, ATP-dependent helicase activity, DNA binding, hydrolase activity, acting on acid anhydrides, metal ion binding, nucleic acid binding, protein binding Human BRIX1 HPA UniProtKB {GO:0003674=GO_REF:0000015, GO:0042254=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q8TDN6 Ribosome biogenesis protein BRX1 homolog protein 20110516 {GO:0003674=ND, GO:0042254=IEA, GO:0005730=IDA, GO:0005634=IDA} ribosome biogenesis nucleolus, nucleus molecular_function Human BRK1 Reactome UniProtKB {GO:0008284=GO_REF:0000019, GO:0030036=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0048870=GO_REF:0000019, GO:0005856=GO_REF:0000039, GO:0038096=Reactome:REACT_160123, GO:0001701=GO_REF:0000019, GO:0005829=Reactome:REACT_160291} Q8WUW1 Protein BRICK1 protein 20111015 {GO:0008284=IEA, GO:0030036=IEA, GO:0045087=TAS, GO:0048870=IEA, GO:0005856=IEA, GO:0038096=TAS, GO:0001701=IEA, GO:0005829=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, actin cytoskeleton organization, cell motility, in utero embryonic development, innate immune response, positive regulation of cell proliferation cytoskeleton, cytosol Human BRMS1 IntAct UniProtKB {GO:0005515=PMID:21258344, GO:0005737=PMID:20830743, GO:0051059=PMID:17000776, GO:0009987=GO_REF:0000019, GO:2000210=PMID:17000776, GO:0006915=GO_REF:0000037, GO:0032088=PMID:17000776, GO:0005634=PMID:17000776, GO:0045892=PMID:20830743, GO:0006351=GO_REF:0000037, GO:0090312=PMID:17000776} Q9HCU9 Breast cancer metastasis-suppressor 1 protein 20130415 {GO:0005515=IPI, GO:0005737=IDA, GO:0051059=IDA, GO:0009987=IEA, GO:2000210=IMP, GO:0006915=IEA, GO:0032088=IDA, GO:0005634=IDA, GO:0045892=IDA, GO:0006351=IEA, GO:0090312=IDA} apoptotic process, cellular process, negative regulation of NF-kappaB transcription factor activity, negative regulation of transcription, DNA-dependent, positive regulation of anoikis, positive regulation of protein deacetylation, transcription, DNA-dependent cytoplasm, nucleus NF-kappaB binding, protein binding Human UniProtKB:Q92769 BRMS1L UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0040008=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q5PSV4 Breast cancer metastasis-suppressor 1-like protein protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0040008=IEA, GO:0006351=IEA} regulation of growth, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus Human UniProtKB-SubCell:SL-0191 BROX UniProtKB UniProtKB {GO:0016020=GO_REF:0000039} Q5VW32 BRO1 domain-containing protein BROX protein 20130413 {GO:0016020=IEA} membrane Human UniProtKB-SubCell:SL-0162 BRPF1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0070776=PMID:18794358, GO:0005886=GO_REF:0000052, GO:0043966=PMID:16387653, GO:0005634=PMID:18794358, GO:0008270=GO_REF:0000002, GO:0045893=PMID:18794358, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P55201 Peregrin protein 20101115 {GO:0005737=IDA, GO:0070776=IDA, GO:0005886=IDA, GO:0043966=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0045893=IDA, GO:0003677=IEA, GO:0006351=IEA} histone H3 acetylation, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent MOZ/MORF histone acetyltransferase complex, cytoplasm, nucleus, plasma membrane DNA binding, zinc ion binding Human BRPF3 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0070776=PMID:16387653, GO:0043966=PMID:16387653, GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_21347, GO:0008270=GO_REF:0000002, GO:0005829=Reactome:REACT_21347} Q9ULD4 Bromodomain and PHD finger-containing protein 3 protein 20130415 {GO:0005515=IPI, GO:0070776=IDA, GO:0043966=IDA, GO:0007596=TAS, GO:0002576=TAS, GO:0030168=TAS, GO:0005576=TAS, GO:0008270=IEA, GO:0005829=TAS} blood coagulation, histone H3 acetylation, platelet activation, platelet degranulation MOZ/MORF histone acetyltransferase complex, cytosol, extracellular region protein binding, zinc ion binding Human UniProtKB:P16333 BRSK1 HPA UniProtKB {GO:0005813=GO_REF:0000024, GO:0030054=GO_REF:0000052, GO:0000287=PMID:14976552, GO:0005886=GO_REF:0000052, GO:0019901=GO_REF:0000019, GO:0043015=GO_REF:0000024, GO:0031572=PMID:15150265, GO:0005730=GO_REF:0000052, GO:0050321=PMID:21985311, GO:0005634=GO_REF:0000052, GO:0030010=GO_REF:0000024, GO:0007409=GO_REF:0000024, GO:0005524=PMID:15150265, GO:0006974=PMID:15150265, GO:0007269=GO_REF:0000024, GO:0008021=GO_REF:0000024, GO:0051298=GO_REF:0000024, GO:0005737=PMID:15150265, GO:0004672=GO_REF:0000002, GO:0004674=PMID:15150265, GO:0010212=PMID:15150265, GO:0030182=GO_REF:0000024, GO:0006468=PMID:15150265, GO:0009411=PMID:15150265} Q8TDC3 Serine/threonine-protein kinase BRSK1 protein 20101115 {GO:0005813=ISS, GO:0030054=IDA, GO:0000287=IDA, GO:0005886=IDA, GO:0019901=IEA, GO:0043015=ISS, GO:0031572=IDA, GO:0005730=IDA, GO:0050321=IDA, GO:0005634=IDA, GO:0030010=ISS, GO:0007409=ISS, GO:0005524=IC, GO:0006974=IDA, GO:0007269=ISS, GO:0008021=ISS, GO:0051298=ISS, GO:0005737=IDA, GO:0004672=IEA, GO:0004674=IDA, GO:0010212=IDA, GO:0030182=ISS, GO:0006468=IDA, GO:0009411=IDA} G2 DNA damage checkpoint, axonogenesis, centrosome duplication, establishment of cell polarity, neuron differentiation, neurotransmitter secretion, protein phosphorylation, response to DNA damage stimulus, response to UV, response to ionizing radiation cell junction, centrosome, cytoplasm, nucleolus, nucleus, plasma membrane, synaptic vesicle ATP binding, gamma-tubulin binding, magnesium ion binding, protein kinase activity, protein kinase binding, protein serine/threonine kinase activity, tau-protein kinase activity Human BRSK2 UniProtKB UniProtKB {GO:0005813=PMID:23029325, GO:0048471=GO_REF:0000039, GO:0000287=PMID:14976552, GO:0031532=PMID:22669945, GO:0019901=GO_REF:0000019, GO:0005783=GO_REF:0000039, GO:0050321=PMID:21985311, GO:0030010=GO_REF:0000024, GO:0007409=GO_REF:0000024, GO:0006887=GO_REF:0000037, GO:0005524=PMID:14976552, GO:0005737=PMID:22713462, GO:0007067=GO_REF:0000037, GO:0018105=GO_REF:0000019, GO:0070059=PMID:22713462, GO:0016301=GO_REF:0000038, GO:0004674=PMID:14976552, GO:0000086=PMID:23029325, GO:0030182=GO_REF:0000024, GO:0006468=PMID:14976552, GO:0061178=GO_REF:0000024, GO:0051301=GO_REF:0000037} Q8IWQ3 Serine/threonine-protein kinase BRSK2 protein 20121011 {GO:0005813=IDA, GO:0048471=IEA, GO:0000287=IDA, GO:0031532=IMP, GO:0019901=IEA, GO:0005783=IEA, GO:0050321=IDA, GO:0030010=ISS, GO:0007409=ISS, GO:0006887=IEA, GO:0005524=IDA, GO:0005737=IDA, GO:0007067=IEA, GO:0018105=IEA, GO:0070059=IMP, GO:0016301=IEA, GO:0004674=IDA, GO:0000086=IMP, GO:0030182=ISS, GO:0006468=IDA, GO:0061178=ISS, GO:0051301=IEA} G2/M transition of mitotic cell cycle, actin cytoskeleton reorganization, axonogenesis, cell division, establishment of cell polarity, exocytosis, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, mitosis, neuron differentiation, peptidyl-serine phosphorylation, protein phosphorylation, regulation of insulin secretion involved in cellular response to glucose stimulus centrosome, cytoplasm, endoplasmic reticulum, perinuclear region of cytoplasm ATP binding, kinase activity, magnesium ion binding, protein kinase binding, protein serine/threonine kinase activity, tau-protein kinase activity Human BRWD1 HPA UniProtKB {GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0006357=GO_REF:0000019, GO:0008360=PMID:21834987, GO:0007010=PMID:21834987, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037} Q9NSI6 Bromodomain and WD repeat-containing protein 1 protein 20110516 {GO:0003674=ND, GO:0005737=IDA, GO:0006357=IEA, GO:0008360=IMP, GO:0007010=IMP, GO:0005730=IDA, GO:0005634=IDA, GO:0006351=IEA} cytoskeleton organization, regulation of cell shape, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, nucleolus, nucleus molecular_function Human BRWD3 UniProtKB UniProtKB {GO:0008360=PMID:21834987, GO:0007010=PMID:21834987} Q6RI45 Bromodomain and WD repeat-containing protein 3 protein 20110926 {GO:0008360=IMP, GO:0007010=IMP} cytoskeleton organization, regulation of cell shape Human BSCL2 UniProtKB UniProtKB {GO:0016042=GO_REF:0000037, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0008219=GO_REF:0000037, GO:0050995=GO_REF:0000024, GO:0019915=PMID:19278620, GO:0045444=GO_REF:0000024, GO:0030176=PMID:14981520, GO:0034389=PMID:19278620} Q96G97 Seipin protein 20120618 {GO:0016042=IEA, GO:0008150=ND, GO:0003674=ND, GO:0008219=IEA, GO:0050995=ISS, GO:0019915=IMP, GO:0045444=ISS, GO:0030176=IDA, GO:0034389=IMP} biological_process, cell death, fat cell differentiation, lipid catabolic process, lipid particle organization, lipid storage, negative regulation of lipid catabolic process integral to endoplasmic reticulum membrane molecular_function Human BSDC1 null null {} null null null null {} null null null BSG Reactome UniProtKB {GO:0042470=GO_REF:0000039, GO:0005886=Reactome:REACT_16988, GO:0007566=GO_REF:0000019, GO:0043434=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0050900=Reactome:REACT_12051, GO:0005537=GO_REF:0000037, GO:0051591=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0042383=GO_REF:0000019, GO:0046697=GO_REF:0000019, GO:0000139=Reactome:REACT_12637, GO:0016020=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0006090=Reactome:REACT_2071, GO:0042475=GO_REF:0000019, GO:0045121=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0002080=GO_REF:0000019, GO:0046689=GO_REF:0000019, GO:0007166=PMID:9767135} P35613 Basigin protein 20071128 {GO:0042470=IEA, GO:0005886=TAS, GO:0007566=IEA, GO:0043434=IEA, GO:0044281=TAS, GO:0050900=TAS, GO:0005537=IEA, GO:0051591=IEA, GO:0005739=IEA, GO:0042383=IEA, GO:0046697=IEA, GO:0000139=TAS, GO:0016020=IEA, GO:0007596=TAS, GO:0006090=TAS, GO:0042475=IEA, GO:0045121=IEA, GO:0016021=IEA, GO:0002080=IEA, GO:0046689=IEA, GO:0007166=TAS} blood coagulation, cell surface receptor signaling pathway, decidualization, embryo implantation, leukocyte migration, odontogenesis of dentin-containing tooth, pyruvate metabolic process, response to cAMP, response to mercury ion, response to peptide hormone stimulus, small molecule metabolic process Golgi membrane, acrosomal membrane, integral to membrane, melanosome, membrane, membrane raft, mitochondrion, plasma membrane, sarcolemma mannose binding Human BSN HPA UniProtKB {GO:0048786=GO_REF:0000019, GO:0044306=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0030054=GO_REF:0000037, GO:0015630=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0007268=PMID:10329005, GO:0005634=GO_REF:0000052, GO:0030425=GO_REF:0000024, GO:0046872=GO_REF:0000037} Q9UPA5 Protein bassoon protein 20110516 {GO:0048786=IEA, GO:0044306=IEA, GO:0005737=IDA, GO:0030054=IEA, GO:0015630=IDA, GO:0005730=IDA, GO:0007268=TAS, GO:0005634=IDA, GO:0030425=ISS, GO:0046872=IEA} synaptic transmission cell junction, cytoplasm, dendrite, microtubule cytoskeleton, neuron projection terminus, nucleolus, nucleus, presynaptic active zone metal ion binding Human BSND Reactome UniProtKB {GO:0016323=GO_REF:0000024, GO:0043234=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_160109, GO:0005887=GO_REF:0000024, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000024, GO:0017081=GO_REF:0000019} Q8WZ55 Barttin protein 20121214 {GO:0016323=ISS, GO:0043234=ISS, GO:0005737=IEA, GO:0034220=TAS, GO:0005886=TAS, GO:0005887=ISS, GO:0055085=TAS, GO:0005254=ISS, GO:0017081=IEA} ion transmembrane transport, transmembrane transport basolateral plasma membrane, cytoplasm, integral to plasma membrane, plasma membrane, protein complex chloride channel activity, chloride channel regulator activity Human BSPRY HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0048471=GO_REF:0000019, GO:0016020=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006816=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0005925=GO_REF:0000052, GO:0031252=GO_REF:0000019} Q5W0U4 B box and SPRY domain-containing protein protein 20111111 {GO:0005737=IDA, GO:0048471=IEA, GO:0016020=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006816=IEA, GO:0008270=IEA, GO:0005925=IDA, GO:0031252=IEA} calcium ion transport cell leading edge, cytoplasm, focal adhesion, membrane, nucleolus, nucleus, perinuclear region of cytoplasm zinc ion binding Human BST1 PINC UniProtKB {GO:0003953=GO_REF:0000003, GO:0005886=GO_REF:0000039, GO:0006959=PMID:8202488, GO:0007275=PMID:8202488, GO:0031225=GO_REF:0000037, GO:0019898=PMID:8202488} Q10588 ADP-ribosyl cyclase 2 protein 20031119 {GO:0003953=IEA, GO:0005886=IEA, GO:0006959=TAS, GO:0007275=TAS, GO:0031225=IEA, GO:0019898=TAS} humoral immune response, multicellular organismal development anchored to membrane, extrinsic to membrane, plasma membrane NAD+ nucleosidase activity Human BST2 GOC UniProtKB {GO:0005515=PMID:19564354, GO:0030308=PMID:22065321, GO:0005886=PMID:19036818, GO:0008283=PMID:7607676, GO:0035456=GO_REF:0000024, GO:0035455=GO_REF:0000024, GO:0007267=PMID:7607676, GO:0031225=GO_REF:0000037, GO:0042803=PMID:20399176, GO:0051607=PMID:20399176, GO:0016324=GO_REF:0000024, GO:0005737=PMID:22065321, GO:0044459=PMID:20399176, GO:0006959=PMID:7607676, GO:0002737=PMID:19564354, GO:0032956=GO_REF:0000024, GO:0004871=PMID:12761501, GO:0034341=GO_REF:0000024, GO:0043123=PMID:12761501, GO:0045071=PMID:20943977, GO:0030336=PMID:22065321, GO:0005794=GO_REF:0000039, GO:0009986=GO_REF:0000024, GO:0005770=GO_REF:0000039, GO:0007275=PMID:7607676, GO:0009615=PMID:19036818, GO:1901253=PMID:20686043, GO:0007165=PMID:12761501, GO:0042113=GO_REF:0000037, GO:0005887=PMID:7607676, GO:0045087=PMID:19036818, GO:0008191=PMID:22065321, GO:0045121=GO_REF:0000039} Q10589 Bone marrow stromal antigen 2 protein 20130413 {GO:0005515=IPI, GO:0030308=IDA, GO:0005886=IDA, GO:0008283=TAS, GO:0035456=ISS, GO:0035455=ISS, GO:0007267=TAS, GO:0031225=IEA, GO:0042803=IPI, GO:0051607=IDA, GO:0016324=ISS, GO:0005737=IDA, GO:0044459=IDA, GO:0006959=TAS, GO:0002737=IDA, GO:0032956=ISS, GO:0004871=IMP, GO:0034341=ISS, GO:0043123=IMP, GO:0045071=IDA, GO:0030336=IDA, GO:0005794=IEA, GO:0009986=ISS, GO:0005770=IEA, GO:0007275=TAS, GO:0009615=IDA, GO:1901253=IDA, GO:0007165=IMP, GO:0042113=IEA, GO:0005887=TAS, GO:0045087=IDA, GO:0008191=IDA, GO:0045121=IEA} B cell activation, cell proliferation, cell-cell signaling, defense response to virus, humoral immune response, innate immune response, multicellular organismal development, negative regulation of cell growth, negative regulation of cell migration, negative regulation of egress of virus within host cell, negative regulation of plasmacytoid dendritic cell cytokine production, negative regulation of viral genome replication, positive regulation of I-kappaB kinase/NF-kappaB cascade, regulation of actin cytoskeleton organization, response to interferon-alpha, response to interferon-beta, response to interferon-gamma, response to virus, signal transduction Golgi apparatus, anchored to membrane, apical plasma membrane, cell surface, cytoplasm, integral to plasma membrane, late endosome, membrane raft, plasma membrane, plasma membrane part metalloendopeptidase inhibitor activity, protein binding, protein homodimerization activity, signal transducer activity Human BTAF1 UniProtKB UniProtKB {GO:0003700=PMID:9342322, GO:0004386=GO_REF:0000037, GO:0005634=GO_REF:0000029, GO:0045892=PMID:9488487, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000037} O14981 TATA-binding protein-associated factor 172 protein 20020606 {GO:0003700=NAS, GO:0004386=IEA, GO:0005634=NAS, GO:0045892=NAS, GO:0005524=IEA, GO:0003677=IEA} negative regulation of transcription, DNA-dependent nucleus ATP binding, DNA binding, helicase activity, sequence-specific DNA binding transcription factor activity Human BTBD1 LIFEdb UniProtKB {GO:0005515=PMID:12878161, GO:0043234=GO_REF:0000054, GO:0016567=GO_REF:0000041, GO:0000932=PMID:12878161, GO:0043393=PMID:11179693} Q9H0C5 BTB/POZ domain-containing protein 1 protein 20100607 {GO:0005515=IPI, GO:0043234=IDA, GO:0016567=IEA, GO:0000932=IDA, GO:0043393=NAS} protein ubiquitination, regulation of protein binding cytoplasmic mRNA processing body, protein complex protein binding Human BTBD10 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9BSF8 BTB/POZ domain-containing protein 10 protein 20111111 {GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA} cytoplasm, nucleolus, nucleus Human BTBD16 null null {} null null null null {} null null null BTBD2 IntAct UniProtKB {GO:0005515=PMID:19615732, GO:0000932=PMID:12878161} Q9BX70 BTB/POZ domain-containing protein 2 protein 20130415 {GO:0005515=IPI, GO:0000932=IDA} cytoplasmic mRNA processing body protein binding Human UniProtKB:Q7L5N1 BTBD3 null null {} null null null null {} null null null BTBD6 UniProtKB UniProtKB {GO:0000932=GO_REF:0000039} Q96KE9 BTB/POZ domain-containing protein 6 protein 20130413 {GO:0000932=IEA} cytoplasmic mRNA processing body Human UniProtKB-SubCell:SL-0230 BTBD7 null null {} null null null null {} null null null BTBD8 HPA UniProtKB {GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q5XKL5 BTB/POZ domain-containing protein 8 protein 20101115 {GO:0005730=IDA, GO:0005634=IDA} nucleolus, nucleus NOT Human BTBD9 InterPro UniProtKB {GO:0007155=GO_REF:0000002} Q96Q07 BTB/POZ domain-containing protein 9 protein 20130413 {GO:0007155=IEA} cell adhesion Human InterPro:IPR000421 BTC Reactome UniProtKB {GO:0008284=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0005154=PMID:8144591, GO:0048011=Reactome:REACT_11061, GO:0005886=GO_REF:0000039, GO:0048015=Reactome:REACT_12464, GO:0005576=Reactome:REACT_147854, GO:0005615=GO_REF:0000039, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0051781=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0008083=GO_REF:0000037} P35070 Probetacellulin protein 20130301 {GO:0008284=IEA, GO:0043066=IEA, GO:0005154=TAS, GO:0048011=TAS, GO:0005886=IEA, GO:0048015=TAS, GO:0005576=TAS, GO:0005615=IEA, GO:0007173=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0051781=IEA, GO:0016021=IEA, GO:0008083=IEA} epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, negative regulation of apoptotic process, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of cell division, positive regulation of cell proliferation extracellular region, extracellular space, integral to membrane, plasma membrane epidermal growth factor receptor binding, growth factor activity Human BTD PINC UniProtKB {GO:0047708=GO_REF:0000003, GO:0006807=GO_REF:0000002, GO:0008544=PMID:7550325, GO:0016811=GO_REF:0000002, GO:0005730=GO_REF:0000019, GO:0004075=PMID:7509806, GO:0045177=GO_REF:0000019, GO:0043204=GO_REF:0000019, GO:0007417=PMID:7550325, GO:0005615=GO_REF:0000039} P43251 Biotinidase protein 20030904 {GO:0047708=IEA, GO:0006807=IEA, GO:0008544=TAS, GO:0016811=IEA, GO:0005730=IEA, GO:0004075=TAS, GO:0045177=IEA, GO:0043204=IEA, GO:0007417=TAS, GO:0005615=IEA} central nervous system development, epidermis development, nitrogen compound metabolic process apical part of cell, extracellular space, nucleolus, perikaryon biotin carboxylase activity, biotinidase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides Human BTF3 PINC UniProtKB {GO:0006355=GO_REF:0000037, GO:0006366=PMID:2320128, GO:0005634=GO_REF:0000039, GO:0001701=GO_REF:0000019} P20290 Transcription factor BTF3 protein 20030904 {GO:0006355=IEA, GO:0006366=TAS, GO:0005634=IEA, GO:0001701=IEA} in utero embryonic development, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter nucleus Human BTF3L4 null null {} null null null null {} null null null BTG1 IntAct UniProtKB {GO:0003712=PMID:11420681, GO:0005515=PMID:16189514, GO:0006355=PMID:11420681, GO:0030308=PMID:15033446, GO:0008285=PMID:11420681, GO:0005634=PMID:11420681, GO:0042981=PMID:9690562, GO:0045766=PMID:15033446, GO:0005737=PMID:11420681, GO:0016477=PMID:15033446, GO:0045663=PMID:11420681, GO:0019899=PMID:8663146, GO:0019900=PMID:9820826, GO:0045603=PMID:15033446} P62324 Protein BTG1 protein 20130415 {GO:0003712=NAS, GO:0005515=IPI, GO:0006355=NAS, GO:0030308=NAS, GO:0008285=IDA, GO:0005634=IDA, GO:0042981=IMP, GO:0045766=IMP, GO:0005737=IDA, GO:0016477=NAS, GO:0045663=IDA, GO:0019899=IPI, GO:0019900=NAS, GO:0045603=IMP} cell migration, negative regulation of cell growth, negative regulation of cell proliferation, positive regulation of angiogenesis, positive regulation of endothelial cell differentiation, positive regulation of myoblast differentiation, regulation of apoptotic process, regulation of transcription, DNA-dependent cytoplasm, nucleus enzyme binding, kinase binding, protein binding, transcription cofactor activity Human UniProtKB:Q9UFF9 BTG2 IntAct UniProtKB {GO:0005515=PMID:11136725, GO:0017148=PMID:23236473, GO:0008306=GO_REF:0000019, GO:0014070=GO_REF:0000019, GO:0021542=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:2000178=GO_REF:0000019, GO:0008285=PMID:23236473, GO:0021954=GO_REF:0000019, GO:0060213=PMID:18337750, GO:0043434=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0006974=PMID:8944033, GO:0031175=PMID:18773938, GO:0009612=GO_REF:0000019, GO:0001077=GO_REF:0000019, GO:0006281=PMID:8944033, GO:0051602=GO_REF:0000019, GO:0006479=GO_REF:0000019} P78543 Protein BTG2 protein 20130415 {GO:0005515=IPI, GO:0017148=IDA, GO:0008306=IEA, GO:0014070=IEA, GO:0021542=IEA, GO:0043066=IEA, GO:2000178=IEA, GO:0008285=IMP, GO:0021954=IEA, GO:0060213=IDA, GO:0043434=IEA, GO:0009952=IEA, GO:0006974=IDA, GO:0031175=IMP, GO:0009612=IEA, GO:0001077=IEA, GO:0006281=TAS, GO:0051602=IEA, GO:0006479=IEA} DNA repair, anterior/posterior pattern specification, associative learning, central nervous system neuron development, dentate gyrus development, negative regulation of apoptotic process, negative regulation of cell proliferation, negative regulation of neural precursor cell proliferation, negative regulation of translation, neuron projection development, positive regulation of nuclear-transcribed mRNA poly(A) tail shortening, protein methylation, response to DNA damage stimulus, response to electrical stimulus, response to mechanical stimulus, response to organic cyclic compound, response to peptide hormone stimulus RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, protein binding Human UniProtKB:Q9UIV1 BTG3 PINC UniProtKB {GO:0005737=PMID:9632145, GO:0008285=PMID:9632145, GO:0045930=PMID:9632145} Q14201 Protein BTG3 protein 20030904 {GO:0005737=IDA, GO:0008285=TAS, GO:0045930=IDA} negative regulation of cell proliferation, negative regulation of mitotic cell cycle cytoplasm Human BTG4 UniProtKB UniProtKB {GO:0008285=PMID:10995567, GO:0045930=GO_REF:0000019, GO:0030182=PMID:10995567, GO:0007050=PMID:10995567, GO:0005575=GO_REF:0000015} Q9NY30 Protein BTG4 protein 20011002 {GO:0008285=TAS, GO:0045930=IEA, GO:0030182=TAS, GO:0007050=TAS, GO:0005575=ND} cell cycle arrest, negative regulation of cell proliferation, negative regulation of mitotic cell cycle, neuron differentiation cellular_component Human BTK HPA UniProtKB {GO:0005515=PMID:22939624, GO:0050853=PMID:19290921, GO:0034142=Reactome:REACT_6894, GO:0019722=PMID:15046600, GO:0005886=Reactome:REACT_118781, GO:0045579=PMID:19290921, GO:0007249=GO_REF:0000019, GO:0005634=PMID:19290921, GO:0046872=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0042802=PMID:11577348, GO:0005829=Reactome:REACT_150418, GO:0035556=GO_REF:0000002, GO:0005737=PMID:15046600, GO:0005543=GO_REF:0000002, GO:0051092=PMID:19290921, GO:0002755=Reactome:REACT_6788, GO:0002902=PMID:19290921, GO:0048469=GO_REF:0000019, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0005547=PMID:17823121, GO:0018108=GO_REF:0000019, GO:0031410=GO_REF:0000019, GO:0002224=Reactome:REACT_6966, GO:0097190=PMID:8688094, GO:0005524=GO_REF:0000038, GO:0006351=GO_REF:0000037, GO:0002721=PMID:19290921, GO:0002250=PMID:19290921, GO:0042113=PMID:19290921, GO:0045087=Reactome:REACT_6802, GO:0007498=PMID:8013627, GO:0006468=PMID:11913944, GO:0045121=PMID:15046600, GO:0004713=GO_REF:0000038, GO:0004715=PMID:19290921} Q5JY90 Tyrosine-protein kinase BTK protein 20101115 {GO:0005515=IPI, GO:0050853=TAS, GO:0034142=TAS, GO:0019722=TAS, GO:0005886=TAS, GO:0045579=TAS, GO:0007249=IEA, GO:0005634=TAS, GO:0046872=IEA, GO:0043231=IDA, GO:0042802=IPI, GO:0005829=TAS, GO:0035556=IEA, GO:0005737=TAS, GO:0005543=IEA, GO:0051092=TAS, GO:0002755=TAS, GO:0002902=TAS, GO:0048469=IEA, GO:0038124=TAS, GO:0038123=TAS, GO:0034134=TAS, GO:0005547=IDA, GO:0018108=IEA, GO:0031410=IEA, GO:0002224=TAS, GO:0097190=TAS, GO:0005524=IEA, GO:0006351=IEA, GO:0002721=TAS, GO:0002250=TAS, GO:0042113=TAS, GO:0045087=TAS, GO:0007498=TAS, GO:0006468=TAS, GO:0045121=IDA, GO:0004713=IEA, GO:0004715=TAS} B cell activation, B cell receptor signaling pathway, I-kappaB kinase/NF-kappaB cascade, MyD88-dependent toll-like receptor signaling pathway, adaptive immune response, apoptotic signaling pathway, calcium-mediated signaling, cell maturation, innate immune response, intracellular signal transduction, mesoderm development, peptidyl-tyrosine phosphorylation, positive regulation of B cell differentiation, positive regulation of NF-kappaB transcription factor activity, protein phosphorylation, regulation of B cell apoptotic process, regulation of B cell cytokine production, toll-like receptor 2 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, transcription, DNA-dependent cytoplasm, cytoplasmic vesicle, cytosol, intracellular membrane-bounded organelle, membrane raft, nucleus, plasma membrane ATP binding, identical protein binding, metal ion binding, non-membrane spanning protein tyrosine kinase activity, phosphatidylinositol-3,4,5-trisphosphate binding, phospholipid binding, protein binding, protein tyrosine kinase activity Human BTLA Reactome UniProtKB {GO:0002768=GO_REF:0000019, GO:0005886=Reactome:REACT_19406, GO:0046642=GO_REF:0000019, GO:0005887=GO_REF:0000019, GO:0031295=Reactome:REACT_19344, GO:0030889=GO_REF:0000019, GO:0004872=GO_REF:0000019, GO:0009897=GO_REF:0000019} Q7Z6A9 B- and T-lymphocyte attenuator protein 20070515 {GO:0002768=IEA, GO:0005886=TAS, GO:0046642=IEA, GO:0005887=IEA, GO:0031295=TAS, GO:0030889=IEA, GO:0004872=IEA, GO:0009897=IEA} T cell costimulation, immune response-regulating cell surface receptor signaling pathway, negative regulation of B cell proliferation, negative regulation of alpha-beta T cell proliferation external side of plasma membrane, integral to plasma membrane, plasma membrane receptor activity Human BTN1A1 PINC UniProtKB {GO:0005887=PMID:8611614, GO:0004872=PMID:8611614, GO:0005576=GO_REF:0000039} Q13410 Butyrophilin subfamily 1 member A1 protein 20030904 {GO:0005887=TAS, GO:0004872=TAS, GO:0005576=IEA} extracellular region, integral to plasma membrane receptor activity Human BTN2A1 PINC UniProtKB {GO:0006629=PMID:9382921, GO:0003674=GO_REF:0000015, GO:0005887=PMID:9382921} Q7KYR7 Butyrophilin subfamily 2 member A1 protein 20050308 {GO:0006629=TAS, GO:0003674=ND, GO:0005887=TAS} lipid metabolic process integral to plasma membrane molecular_function Human BTN2A2 UniProtKB UniProtKB {GO:0031324=GO_REF:0000024, GO:0046007=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0050710=GO_REF:0000024} Q8WVV5 Butyrophilin subfamily 2 member A2 protein 20110401 {GO:0031324=ISS, GO:0046007=ISS, GO:0016021=IEA, GO:0050710=ISS} negative regulation of activated T cell proliferation, negative regulation of cellular metabolic process, negative regulation of cytokine secretion integral to membrane Human UniProtKB:A4QPC6 BTN3A1 IntAct UniProtKB {GO:0005515=PMID:21982860, GO:0072643=PMID:21918970, GO:0050852=PMID:21918970, GO:0050663=PMID:21918970, GO:0005886=PMID:21918970, GO:0050798=PMID:21918970, GO:0016021=GO_REF:0000037} O00481 Butyrophilin subfamily 3 member A1 protein 20130415 {GO:0005515=IPI, GO:0072643=IMP, GO:0050852=IDA, GO:0050663=IDA, GO:0005886=IDA, GO:0050798=IMP, GO:0016021=IEA} T cell receptor signaling pathway, activated T cell proliferation, cytokine secretion, interferon-gamma secretion integral to membrane, plasma membrane protein binding Human UniProtKB:P04155 BTN3A2 UniProtKB UniProtKB {GO:0072643=PMID:21918970, GO:0005886=PMID:22767497, GO:0016021=GO_REF:0000037, GO:0002456=PMID:22767497} P78410 Butyrophilin subfamily 3 member A2 protein 20121030 {GO:0072643=IMP, GO:0005886=IDA, GO:0016021=IEA, GO:0002456=IMP} T cell mediated immunity, interferon-gamma secretion integral to membrane, plasma membrane Human BTN3A3 UniProtKB UniProtKB {GO:0005886=PMID:22767497, GO:0016021=GO_REF:0000037, GO:0002456=PMID:22767497} O00478 Butyrophilin subfamily 3 member A3 protein 20121030 {GO:0005886=IDA, GO:0016021=IEA, GO:0002456=IMP} T cell mediated immunity integral to membrane, plasma membrane Human BTNL2 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9UIR0 Butyrophilin-like protein 2 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 BTRC BHF-UCL UniProtKB {GO:0005515=PMID:20708156, GO:0006511=PMID:15448698, GO:0004842=PMID:15448698, GO:0016567=PMID:16885022, GO:0008013=GO_REF:0000019, GO:0045309=GO_REF:0000019, GO:0045879=PMID:11001584, GO:0005634=GO_REF:0000039, GO:0031145=Reactome:REACT_6828, GO:0005829=Reactome:REACT_118856, GO:0031648=PMID:16885022, GO:0030163=GO_REF:0000019, GO:0006470=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0051726=GO_REF:0000019, GO:0016032=Reactome:REACT_6185, GO:0016055=GO_REF:0000037, GO:0043122=GO_REF:0000019, GO:0000209=GO_REF:0000019, GO:0051437=Reactome:REACT_6821, GO:0051439=Reactome:REACT_6837, GO:0045862=PMID:16885022, GO:0007165=PMID:9990853, GO:0033598=GO_REF:0000019, GO:0071407=GO_REF:0000019, GO:0061136=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0042753=GO_REF:0000019, GO:0000278=Reactome:REACT_152, GO:0045893=GO_REF:0000019, GO:0045892=PMID:19966869, GO:0060444=GO_REF:0000019, GO:0019005=PMID:19966869} Q9Y297 F-box/WD repeat-containing protein 1A protein 20111117 {GO:0005515=IPI, GO:0006511=IDA, GO:0004842=IDA, GO:0016567=IDA, GO:0008013=IEA, GO:0045309=IEA, GO:0045879=TAS, GO:0005634=IEA, GO:0031145=TAS, GO:0005829=TAS, GO:0031648=IMP, GO:0030163=IEA, GO:0006470=IEA, GO:0046983=IEA, GO:0051726=IEA, GO:0016032=TAS, GO:0016055=IEA, GO:0043122=IEA, GO:0000209=IEA, GO:0051437=TAS, GO:0051439=TAS, GO:0045862=IMP, GO:0007165=TAS, GO:0033598=IEA, GO:0071407=IEA, GO:0061136=IEA, GO:0019048=IEA, GO:0042753=IEA, GO:0000278=TAS, GO:0045893=IEA, GO:0045892=IMP, GO:0060444=IEA, GO:0019005=IDA} Wnt receptor signaling pathway, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, branching involved in mammary gland duct morphogenesis, cellular response to organic cyclic compound, mammary gland epithelial cell proliferation, mitotic cell cycle, negative regulation of smoothened signaling pathway, negative regulation of transcription, DNA-dependent, positive regulation of circadian rhythm, positive regulation of proteolysis, positive regulation of transcription, DNA-dependent, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein catabolic process, protein dephosphorylation, protein destabilization, protein polyubiquitination, protein ubiquitination, regulation of I-kappaB kinase/NF-kappaB cascade, regulation of cell cycle, regulation of proteasomal protein catabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, signal transduction, ubiquitin-dependent protein catabolic process, viral reproduction, virus-host interaction SCF ubiquitin ligase complex, cytosol, nucleus beta-catenin binding, protein binding, protein dimerization activity, protein phosphorylated amino acid binding, ubiquitin-protein ligase activity Human BUB1 Reactome UniProtKB {GO:0005515=PMID:17981135, GO:0000236=Reactome:REACT_682, GO:0007094=PMID:9790499, GO:0000780=GO_REF:0000019, GO:0007093=PMID:9521327, GO:0008283=GO_REF:0000019, GO:0051983=PMID:19487456, GO:0006915=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_150414, GO:0004672=PMID:10198256, GO:0007059=GO_REF:0000037, GO:0004674=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0000087=Reactome:REACT_910, GO:0071173=PMID:15525512, GO:0000777=PMID:19465021, GO:0000776=PMID:22331848, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0007063=PMID:15723797, GO:0016772=GO_REF:0000002, GO:0051301=GO_REF:0000037} O43683 Mitotic checkpoint serine/threonine-protein kinase BUB1 protein 20120924 {GO:0005515=IPI, GO:0000236=TAS, GO:0007094=TAS, GO:0000780=IEA, GO:0007093=TAS, GO:0008283=IEA, GO:0051983=IMP, GO:0006915=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0004672=TAS, GO:0007059=IEA, GO:0004674=IEA, GO:0019048=IEA, GO:0000087=TAS, GO:0071173=IDA, GO:0000777=IDA, GO:0000776=IDA, GO:0000278=TAS, GO:0000090=TAS, GO:0007063=IDA, GO:0016772=IEA, GO:0051301=IEA} M phase of mitotic cell cycle, apoptotic process, cell division, cell proliferation, chromosome segregation, mitotic anaphase, mitotic cell cycle, mitotic cell cycle checkpoint, mitotic prometaphase, mitotic spindle assembly checkpoint, regulation of chromosome segregation, regulation of sister chromatid cohesion, spindle assembly checkpoint, virus-host interaction condensed chromosome kinetochore, condensed nuclear chromosome, centromeric region, cytosol, kinetochore ATP binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, transferase activity, transferring phosphorus-containing groups Human BUB1B BHF-UCL UniProtKB {GO:0005515=PMID:20360068, GO:0007094=Reactome:REACT_2137, GO:0000236=Reactome:REACT_682, GO:0048471=PMID:20531406, GO:0007093=PMID:10477750, GO:0008283=PMID:10477750, GO:0034501=PMID:9660858, GO:0051233=PMID:9763420, GO:0031145=Reactome:REACT_6850, GO:0005829=Reactome:REACT_150414, GO:0005737=GO_REF:0000054, GO:0005680=PMID:10477750, GO:0000087=Reactome:REACT_910, GO:0007051=PMID:15504738, GO:0007091=GO_REF:0000019, GO:0005815=GO_REF:0000039, GO:0048015=PMID:15504738, GO:0006915=GO_REF:0000037, GO:0051436=Reactome:REACT_1041, GO:0071459=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0051439=Reactome:REACT_6837, GO:0007049=PMID:15504738, GO:0007067=PMID:9763420, GO:0000940=PMID:19468067, GO:0004672=PMID:9763420, GO:0004674=GO_REF:0000037, GO:0000777=PMID:19465021, GO:0000776=PMID:22331848, GO:0000075=Reactome:REACT_1538, GO:0000778=GO_REF:0000019, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} O60566 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta protein 20101105 {GO:0005515=IPI, GO:0007094=TAS, GO:0000236=TAS, GO:0048471=IDA, GO:0007093=TAS, GO:0008283=TAS, GO:0034501=IPI, GO:0051233=NAS, GO:0031145=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0005680=TAS, GO:0000087=TAS, GO:0007051=NAS, GO:0007091=IEA, GO:0005815=IEA, GO:0048015=NAS, GO:0006915=IEA, GO:0051436=TAS, GO:0071459=IEA, GO:0005524=IEA, GO:0051439=TAS, GO:0007049=NAS, GO:0007067=NAS, GO:0000940=IDA, GO:0004672=NAS, GO:0004674=IEA, GO:0000777=IDA, GO:0000776=IDA, GO:0000075=TAS, GO:0000778=IEA, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, apoptotic process, cell cycle, cell cycle checkpoint, cell division, cell proliferation, metaphase/anaphase transition of mitotic cell cycle, mitosis, mitotic anaphase, mitotic cell cycle, mitotic cell cycle checkpoint, mitotic prometaphase, mitotic spindle assembly checkpoint, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, phosphatidylinositol-mediated signaling, protein localization to chromosome, centromeric region, protein localization to kinetochore, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, spindle organization anaphase-promoting complex, condensed chromosome kinetochore, condensed chromosome outer kinetochore, condensed nuclear chromosome kinetochore, cytoplasm, cytosol, kinetochore, microtubule organizing center, perinuclear region of cytoplasm, spindle midzone ATP binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human BUB3 HPA UniProtKB {GO:0005515=PMID:17289665, GO:0007094=Reactome:REACT_2137, GO:0000236=Reactome:REACT_682, GO:0051983=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0051436=Reactome:REACT_1041, GO:0031145=Reactome:REACT_6850, GO:0051439=Reactome:REACT_6837, GO:0005829=Reactome:REACT_150414, GO:0000070=GO_REF:0000019, GO:0007126=GO_REF:0000037, GO:0000087=Reactome:REACT_910, GO:0071173=PMID:15525512, GO:0000777=GO_REF:0000039, GO:0000776=PMID:9660858, GO:0000075=Reactome:REACT_1538, GO:0000278=Reactome:REACT_152, GO:0008608=PMID:18199686, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} O43684 Mitotic checkpoint protein BUB3 protein 20080205 {GO:0005515=IPI, GO:0007094=TAS, GO:0000236=TAS, GO:0051983=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0051436=TAS, GO:0031145=TAS, GO:0051439=TAS, GO:0005829=TAS, GO:0000070=IEA, GO:0007126=IEA, GO:0000087=TAS, GO:0071173=IDA, GO:0000777=IEA, GO:0000776=IDA, GO:0000075=TAS, GO:0000278=TAS, GO:0008608=IDA, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, attachment of spindle microtubules to kinetochore, cell cycle checkpoint, cell division, meiosis, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, mitotic sister chromatid segregation, mitotic spindle assembly checkpoint, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, regulation of chromosome segregation, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, spindle assembly checkpoint condensed chromosome kinetochore, cytosol, kinetochore, nucleolus, nucleus protein binding NOT Human BUD13 BHF-UCL UniProtKB {GO:0006406=PMID:15565172, GO:0000398=PMID:15565172, GO:0070274=PMID:15565172} Q9BRD0 BUD13 homolog protein 20111208 {GO:0006406=ISS, GO:0000398=ISS, GO:0070274=ISS} mRNA export from nucleus, mRNA splicing, via spliceosome RES complex Human UniProtKB:P46947 BUD31 PINC UniProtKB {GO:0003700=PMID:7841202, GO:0006357=PMID:7841202, GO:0005634=GO_REF:0000039} P41223 Protein BUD31 homolog protein 20030904 {GO:0003700=TAS, GO:0006357=TAS, GO:0005634=IEA} regulation of transcription from RNA polymerase II promoter nucleus sequence-specific DNA binding transcription factor activity Human BYSL HPA UniProtKB {GO:0005515=PMID:9560222, GO:0007565=PMID:9560222, GO:0005737=GO_REF:0000039, GO:0042254=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0007155=PMID:9560222, GO:0043231=GO_REF:0000052} Q13895 Bystin protein 20101115 {GO:0005515=IPI, GO:0007565=TAS, GO:0005737=IEA, GO:0042254=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0007155=TAS, GO:0043231=IDA} cell adhesion, female pregnancy, ribosome biogenesis cytoplasm, intracellular membrane-bounded organelle, nucleolus, nucleus protein binding Human BZRAP1 IntAct UniProtKB {GO:0005515=PMID:21078624, GO:0005739=PMID:9915832, GO:0008150=GO_REF:0000015, GO:0005737=PMID:9915832, GO:0030156=PMID:9915832} O95153 Peripheral-type benzodiazepine receptor-associated protein 1 protein 20130415 {GO:0005515=IPI, GO:0005739=IDA, GO:0008150=ND, GO:0005737=IDA, GO:0030156=IPI} biological_process cytoplasm, mitochondrion benzodiazepine receptor binding, protein binding Human UniProtKB:O00555 BZW1 UniProtKB UniProtKB {GO:0005737=PMID:10942595, GO:0006355=GO_REF:0000037, GO:0016070=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q7L1Q6 Basic leucine zipper and W2 domain-containing protein 1 protein 20060117 {GO:0005737=IDA, GO:0006355=IEA, GO:0016070=IEA, GO:0006351=IEA} RNA metabolic process, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm Human BZW2 UniProtKB UniProtKB {GO:0016070=GO_REF:0000002, GO:0030154=GO_REF:0000037, GO:0007399=GO_REF:0000037} Q9Y6E2 Basic leucine zipper and W2 domain-containing protein 2 protein 20130413 {GO:0016070=IEA, GO:0030154=IEA, GO:0007399=IEA} RNA metabolic process, cell differentiation, nervous system development Human UniProtKB-KW:KW-0221 C10orf10 null null {} null null null null {} null null null C10orf114 null null {} null null null null {} null null null C10orf118 null null {} null null null null {} null null null C10orf12 null null {} null null null null {} null null null C10orf137 null null {} null null null null {} null null null C10orf2 null null {} null null null null {} null null null C10orf32 null null {} null null null null {} null null null C10orf35 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q96D05 Uncharacterized protein C10orf35 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C10orf54 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9H7M9 Platelet receptor Gi24 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C10orf55 null null {} null null null null {} null null null C10orf62 IntAct UniProtKB {GO:0005515=PMID:19447967} Q5T681 Uncharacterized protein C10orf62 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:Q99750 C10orf76 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q5T2E6 UPF0668 protein C10orf76 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C10orf82 null null {} null null null null {} null null null C10orf88 ENSEMBL UniProtKB {GO:0042802=GO_REF:0000019} Q9H8K7 Uncharacterized protein C10orf88 protein 20130413 {GO:0042802=IEA} identical protein binding Human Ensembl:ENSMUSP00000050128 C10orf90 UniProtKB UniProtKB {GO:0007095=GO_REF:0000019, GO:0005813=PMID:20844083, GO:0005737=PMID:20844083, GO:0030308=GO_REF:0000019, GO:0042826=GO_REF:0000019, GO:0010212=GO_REF:0000019, GO:0050821=GO_REF:0000019, GO:0015629=PMID:20844083, GO:0009411=GO_REF:0000019} Q96M02 Centrosomal protein C10orf90 protein 20110817 {GO:0007095=IEA, GO:0005813=IDA, GO:0005737=IDA, GO:0030308=IEA, GO:0042826=IEA, GO:0010212=IEA, GO:0050821=IEA, GO:0015629=IDA, GO:0009411=IEA} mitotic G2 DNA damage checkpoint, negative regulation of cell growth, protein stabilization, response to UV, response to ionizing radiation actin cytoskeleton, centrosome, cytoplasm histone deacetylase binding Human C11orf1 HPA UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005634=GO_REF:0000052} Q9H5F2 UPF0686 protein C11orf1 protein 20110516 {GO:0003674=ND, GO:0008150=ND, GO:0005634=IDA} biological_process nucleus molecular_function Human C11orf16 null null {} null null null null {} null null null C11orf30 null null {} null null null null {} null null null C11orf45 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q8TAV5 Putative uncharacterized protein C11orf45 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 C11orf48 null null {} null null null null {} null null null C11orf49 HPA UniProtKB {GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9H6J7 UPF0705 protein C11orf49 protein 20111111 {GO:0005730=IDA, GO:0005634=IDA} nucleolus, nucleus NOT Human C11orf52 null null {} null null null null {} null null null C11orf53 null null {} null null null null {} null null null C11orf54 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0016788=PMID:16522806, GO:0008270=PMID:16522806, GO:0005634=GO_REF:0000054} Q9H0W9 Ester hydrolase C11orf54 protein 20130415 {GO:0005515=IPI, GO:0016788=IDA, GO:0008270=IDA, GO:0005634=IDA} nucleus hydrolase activity, acting on ester bonds, protein binding, zinc ion binding Human UniProtKB:Q15645 C11orf57 null null {} null null null null {} null null null C11orf58 null null {} null null null null {} null null null C11orf63 null null {} null null null null {} null null null C11orf65 null null {} null null null null {} null null null C11orf68 null null {} null null null null {} null null null C11orf70 null null {} null null null null {} null null null C11orf71 null null {} null null null null {} null null null C11orf73 UniProtKB UniProtKB {GO:0005622=PMID:22541429, GO:0034605=PMID:22541429, GO:0030324=GO_REF:0000019, GO:0008565=PMID:22541429, GO:0007030=GO_REF:0000019, GO:0030544=PMID:22541429, GO:0005634=PMID:22541429, GO:0015031=PMID:22541429, GO:0006606=PMID:22541429, GO:0005829=PMID:22541429} Q53FT3 Protein Hikeshi protein 20120503 {GO:0005622=IDA, GO:0034605=IDA, GO:0030324=IEA, GO:0008565=IDA, GO:0007030=IEA, GO:0030544=IDA, GO:0005634=IDA, GO:0015031=IDA, GO:0006606=IDA, GO:0005829=IDA} Golgi organization, cellular response to heat, lung development, protein import into nucleus, protein transport cytosol, intracellular, nucleus Hsp70 protein binding, protein transporter activity Human C11orf74 null null {} null null null null {} null null null C11orf80 null null {} null null null null {} null null null C11orf82 ENSEMBL UniProtKB {GO:0071850=GO_REF:0000019, GO:0030097=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:2000270=GO_REF:0000019, GO:0007286=GO_REF:0000019, GO:0033554=GO_REF:0000019, GO:0005634=GO_REF:0000019} E9PQP9 Protein C11orf82 protein 20130413 {GO:0071850=IEA, GO:0030097=IEA, GO:0005737=IEA, GO:2000270=IEA, GO:0007286=IEA, GO:0033554=IEA, GO:0005634=IEA} cellular response to stress, hemopoiesis, mitotic cell cycle arrest, negative regulation of fibroblast apoptotic process, spermatid development cytoplasm, nucleus Human Ensembl:ENSMUSP00000032877 C11orf83 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q6UW78 UPF0723 protein C11orf83 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 C11orf84 null null {} null null null null {} null null null C12orf10 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0003674=GO_REF:0000015, GO:0043473=PMID:16996721, GO:0005634=GO_REF:0000039, GO:0005575=GO_REF:0000015} Q9HB07 UPF0160 protein MYG1, mitochondrial protein 20080604 {GO:0005739=IEA, GO:0003674=ND, GO:0043473=NAS, GO:0005634=IEA, GO:0005575=ND} pigmentation cellular_component, mitochondrion, nucleus molecular_function Human C12orf23 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8WUH6 UPF0444 transmembrane protein C12orf23 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C12orf29 null null {} null null null null {} null null null C12orf39 HPA UniProtKB {GO:0030133=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005576=GO_REF:0000039, GO:0043231=GO_REF:0000052} Q9BT56 Spexin protein 20081203 {GO:0030133=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005576=IEA, GO:0043231=IDA} extracellular region, intracellular membrane-bounded organelle, nucleolus, nucleus, transport vesicle Human C12orf4 null null {} null null null null {} null null null C12orf43 null null {} null null null null {} null null null C12orf44 null null {} null null null null {} null null null C12orf45 null null {} null null null null {} null null null C12orf49 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q9H741 UPF0454 protein C12orf49 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 C12orf5 null null {} null null null null {} null null null C12orf52 null null {} null null null null {} null null null C12orf57 null null {} null null null null {} null null null C12orf63 null null {} null null null null {} null null null C12orf65 UniProtKB UniProtKB {GO:0005739=PMID:20186120, GO:0003747=GO_REF:0000002} Q9H3J6 Probable peptide chain release factor C12orf65, mitochondrial protein 20100305 {GO:0005739=NAS, GO:0003747=IEA} mitochondrion translation release factor activity Human C12orf68 LIFEdb UniProtKB {GO:0005737=GO_REF:0000054} Q52MB2 Uncharacterized protein C12orf68 protein 20100607 {GO:0005737=IDA} cytoplasm Human C12orf75 null null {} null null null null {} null null null C14orf1 LIFEdb UniProtKB {GO:0030133=GO_REF:0000054, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005789=GO_REF:0000039, GO:0016126=GO_REF:0000037, GO:0016021=PMID:10449901} Q9UKR5 Probable ergosterol biosynthetic protein 28 protein 20100607 {GO:0030133=IDA, GO:0003674=ND, GO:0008150=ND, GO:0005789=IEA, GO:0016126=IEA, GO:0016021=NAS} biological_process, sterol biosynthetic process endoplasmic reticulum membrane, integral to membrane, transport vesicle molecular_function Human C14orf119 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039} Q9NWQ9 Uncharacterized protein C14orf119 protein 20130413 {GO:0005739=IEA} mitochondrion Human UniProtKB-SubCell:SL-0173 C14orf142 null null {} null null null null {} null null null C14orf159 BHF-UCL UniProtKB {GO:0005739=GO_REF:0000039, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q7Z3D6 UPF0317 protein C14orf159, mitochondrial protein 20120710 {GO:0005739=IEA, GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component, mitochondrion molecular_function Human C14orf166 HPA UniProtKB {GO:0005515=PMID:11507205, GO:0048471=GO_REF:0000039, GO:0005815=GO_REF:0000039, GO:0045944=PMID:16950395, GO:0019048=GO_REF:0000037, GO:0000993=PMID:16950395, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0072669=PMID:21311021, GO:0006351=GO_REF:0000037, GO:0042802=PMID:15147888} Q9Y224 UPF0568 protein C14orf166 protein 20111111 {GO:0005515=IPI, GO:0048471=IEA, GO:0005815=IEA, GO:0045944=IMP, GO:0019048=IEA, GO:0000993=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0072669=IDA, GO:0006351=IEA, GO:0042802=IPI} positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent, virus-host interaction microtubule organizing center, nucleolus, nucleus, perinuclear region of cytoplasm, tRNA-splicing ligase complex RNA polymerase II core binding, identical protein binding, protein binding NOT Human C14orf169 null null {} null null null null {} null null null C14orf2 InterPro UniProtKB {GO:0005739=GO_REF:0000002} G3V5Q3 Chromosome 14 open reading frame 2, isoform CRA_a protein 20130413 {GO:0005739=IEA} mitochondrion Human InterPro:IPR012574 C14orf80 null null {} null null null null {} null null null C14orf93 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q9H972 Uncharacterized protein C14orf93 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 C15orf38 null null {} null null null null {} null null null C15orf39 null null {} null null null null {} null null null C15orf40 null null {} null null null null {} null null null C15orf41 null null {} null null null null {} null null null C15orf43 null null {} null null null null {} null null null C15orf48 null null {} null null null null {} null null null C15orf57 null null {} null null null null {} null null null C15orf59 null null {} null null null null {} null null null C16orf13 null null {} null null null null {} null null null C16orf45 null null {} null null null null {} null null null C16orf54 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q6UWD8 Transmembrane protein C16orf54 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C16orf58 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q96GQ5 UPF0420 protein C16orf58 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C16orf59 null null {} null null null null {} null null null C16orf62 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q7Z3J2 UPF0505 protein C16orf62 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C16orf70 IntAct UniProtKB {GO:0005515=PMID:16713569} Q9BSU1 UPF0183 protein C16orf70 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:P54252 C16orf72 null null {} null null null null {} null null null C16orf74 null null {} null null null null {} null null null C16orf78 null null {} null null null null {} null null null C16orf80 PINC UniProtKB {GO:0005929=GO_REF:0000019, GO:0007275=PMID:8688464} Q9Y6A4 UPF0468 protein C16orf80 protein 20030904 {GO:0005929=IEA, GO:0007275=TAS} multicellular organismal development cilium Human C16orf87 null null {} null null null null {} null null null C16orf89 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q6UX73 UPF0764 protein C16orf89 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 C17orf49 InterPro UniProtKB {GO:0003682=GO_REF:0000002, GO:0003677=GO_REF:0000002} F8W1H0 Protein C17orf49 protein 20130413 {GO:0003682=IEA, GO:0003677=IEA} DNA binding, chromatin binding Human InterPro:IPR001005 C17orf53 null null {} null null null null {} null null null C17orf59 null null {} null null null null {} null null null C17orf62 IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0016021=GO_REF:0000037} Q9BQA9 Uncharacterized protein C17orf62 protein 20130415 {GO:0005515=IPI, GO:0016021=IEA} integral to membrane protein binding Human UniProtKB:P14921 C17orf70 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0045111=GO_REF:0000052} E7EVV8 Protein C17orf70 protein 20100326 {GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0045111=IDA} cytoplasm, intermediate filament cytoskeleton, nucleolus, nucleus Human C17orf75 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0007283=GO_REF:0000029} Q9HAS0 Protein Njmu-R1 protein 20061026 {GO:0003674=ND, GO:0005575=ND, GO:0007283=NAS} spermatogenesis cellular_component molecular_function Human C17orf85 InterPro UniProtKB {GO:0000166=GO_REF:0000002} Q53F19 Uncharacterized protein C17orf85 protein 20130413 {GO:0000166=IEA} nucleotide binding Human InterPro:IPR012677 C18orf21 null null {} null null null null {} null null null C18orf25 null null {} null null null null {} null null null C18orf32 GOC UniProtKB {GO:0007165=PMID:12761501, GO:0004871=PMID:12761501, GO:0043123=PMID:12761501} Q8TCD1 UPF0729 protein C18orf32 protein 20130413 {GO:0007165=IMP, GO:0004871=IMP, GO:0043123=IMP} positive regulation of I-kappaB kinase/NF-kappaB cascade, signal transduction signal transducer activity Human C18orf54 null null {} null null null null {} null null null C18orf56 null null {} null null null null {} null null null C18orf8 null null {} null null null null {} null null null C19orf10 Reactome UniProtKB {GO:0005793=GO_REF:0000039, GO:0005788=Reactome:REACT_115959, GO:0005576=GO_REF:0000039, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0030968=Reactome:REACT_18356} Q969H8 UPF0556 protein C19orf10 protein 20130301 {GO:0005793=IEA, GO:0005788=TAS, GO:0005576=IEA, GO:0006987=TAS, GO:0044267=TAS, GO:0030968=TAS} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response endoplasmic reticulum lumen, endoplasmic reticulum-Golgi intermediate compartment, extracellular region Human C19orf12 UniProtKB UniProtKB {GO:0008219=GO_REF:0000037, GO:0031966=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q9NSK7 Protein C19orf12 protein 20130413 {GO:0008219=IEA, GO:0031966=IEA, GO:0016021=IEA} cell death integral to membrane, mitochondrial membrane Human UniProtKB-SubCell:SL-0171 C19orf18 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8NEA5 Uncharacterized protein C19orf18 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C19orf21 null null {} null null null null {} null null null C19orf25 IntAct UniProtKB {GO:0005515=PMID:16189514} Q9UFG5 UPF0449 protein C19orf25 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:Q15834 C19orf33 InterPro UniProtKB {GO:0005634=GO_REF:0000002} K7EQG3 Protein C19orf33 protein 20130413 {GO:0005634=IEA} nucleus Human InterPro:IPR026621 C19orf40 InterPro UniProtKB {GO:0006281=GO_REF:0000002, GO:0043240=GO_REF:0000002} K7EKQ4 Protein C19orf40 protein 20130413 {GO:0006281=IEA, GO:0043240=IEA} DNA repair Fanconi anaemia nuclear complex Human InterPro:IPR026985 C19orf43 null null {} null null null null {} null null null C19orf44 null null {} null null null null {} null null null C19orf47 null null {} null null null null {} null null null C19orf52 null null {} null null null null {} null null null C19orf53 null null {} null null null null {} null null null C19orf54 null null {} null null null null {} null null null C19orf55 null null {} null null null null {} null null null C19orf57 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0003674=GO_REF:0000015, GO:0007275=PMID:8228263, GO:0005575=GO_REF:0000015} Q0VDD7 Uncharacterized protein C19orf57 protein 20130415 {GO:0005515=IPI, GO:0003674=ND, GO:0007275=NAS, GO:0005575=ND} multicellular organismal development cellular_component molecular_function, protein binding Human UniProtKB:Q13155 C19orf60 IntAct UniProtKB {GO:0005515=PMID:19060904} Q96EN9 Uncharacterized protein C19orf60 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:Q99750 C19orf66 null null {} null null null null {} null null null C19orf68 IntAct UniProtKB {GO:0005515=PMID:20195357} Q86XI8 Uncharacterized protein C19orf68 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:P17275 C19orf70 null null {} null null null null {} null null null C19orf80 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0010954=PMID:23150577, GO:0070328=PMID:23150577, GO:0005576=GO_REF:0000039, GO:0050746=PMID:23150577} Q6UXH0 Hepatocellular carcinoma-associated protein TD26 protein 20130415 {GO:0005515=IPI, GO:0010954=IDA, GO:0070328=IGI, GO:0005576=IEA, GO:0050746=IMP} positive regulation of protein processing, regulation of lipoprotein metabolic process, triglyceride homeostasis extracellular region protein binding Human UniProtKB:Q96PM5 C1D HPA UniProtKB {GO:0005515=PMID:17412707, GO:0016922=GO_REF:0000019, GO:0000460=PMID:17412707, GO:0003714=GO_REF:0000019, GO:0003723=PMID:17412707, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0005739=GO_REF:0000052, GO:0017053=GO_REF:0000019, GO:0000176=PMID:17412707, GO:0045892=GO_REF:0000019} Q13901 Nuclear nucleic acid-binding protein C1D protein 20111111 {GO:0005515=IPI, GO:0016922=IEA, GO:0000460=IMP, GO:0003714=IEA, GO:0003723=IDA, GO:0005730=IDA, GO:0006915=IEA, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA, GO:0005739=IDA, GO:0017053=IEA, GO:0000176=TAS, GO:0045892=IEA} apoptotic process, maturation of 5.8S rRNA, negative regulation of transcription, DNA-dependent, transcription, DNA-dependent mitochondrion, nuclear exosome (RNase complex), nucleolus, nucleus, transcriptional repressor complex DNA binding, RNA binding, ligand-dependent nuclear receptor binding, protein binding, transcription corepressor activity Human C1GALT1 Reactome UniProtKB {GO:0000139=Reactome:REACT_116072, GO:0001822=PMID:17228361, GO:0016266=Reactome:REACT_115606, GO:0016263=PMID:11677243, GO:0016021=PMID:11677243, GO:0001525=PMID:17228361, GO:0044267=Reactome:REACT_17015, GO:0046872=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0043687=Reactome:REACT_22161} Q9NS00 Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 protein 20111104 {GO:0000139=TAS, GO:0001822=IMP, GO:0016266=TAS, GO:0016263=IDA, GO:0016021=IDA, GO:0001525=IMP, GO:0044267=TAS, GO:0046872=IEA, GO:0030154=IEA, GO:0043687=TAS} O-glycan processing, angiogenesis, cell differentiation, cellular protein metabolic process, kidney development, post-translational protein modification Golgi membrane, integral to membrane glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity, metal ion binding Human C1GALT1C1 Reactome UniProtKB {GO:0004653=Reactome:REACT_115586, GO:0000139=Reactome:REACT_116072, GO:0016266=Reactome:REACT_115606, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q96EU7 C1GALT1-specific chaperone 1 protein 20100721 {GO:0004653=TAS, GO:0000139=TAS, GO:0016266=TAS, GO:0016021=IEA, GO:0044267=TAS, GO:0043687=TAS} O-glycan processing, cellular protein metabolic process, post-translational protein modification Golgi membrane, integral to membrane polypeptide N-acetylgalactosaminyltransferase activity Human C1orf105 null null {} null null null null {} null null null C1orf109 null null {} null null null null {} null null null C1orf110 null null {} null null null null {} null null null C1orf111 null null {} null null null null {} null null null C1orf112 null null {} null null null null {} null null null C1orf115 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9H7X2 Uncharacterized protein C1orf115 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C1orf116 null null {} null null null null {} null null null C1orf122 null null {} null null null null {} null null null C1orf123 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q9NWV4 UPF0587 protein C1orf123 protein 20080829 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human C1orf131 null null {} null null null null {} null null null C1orf174 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039} Q8IYL3 UPF0688 protein C1orf174 protein 20130413 {GO:0005634=IEA} nucleus Human UniProtKB-SubCell:SL-0191 C1orf198 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q9H425 Uncharacterized protein C1orf198 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 C1orf216 null null {} null null null null {} null null null C1orf27 null null {} null null null null {} null null null C1orf35 null null {} null null null null {} null null null C1orf43 UniProtKB UniProtKB {GO:0050662=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0016616=GO_REF:0000002} Q9BWL3 Uncharacterized protein C1orf43 protein 20130413 {GO:0050662=IEA, GO:0016021=IEA, GO:0016616=IEA} integral to membrane coenzyme binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Human UniProtKB-KW:KW-0812 C1orf50 null null {} null null null null {} null null null C1orf51 null null {} null null null null {} null null null C1orf52 null null {} null null null null {} null null null C1orf61 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039} Q13536 Protein CROC-4 protein 20130413 {GO:0005634=IEA} nucleus Human UniProtKB-SubCell:SL-0191 C1orf63 null null {} null null null null {} null null null C1orf64 null null {} null null null null {} null null null C1orf65 null null {} null null null null {} null null null C1orf68 null null {} null null null null {} null null null C1orf74 null null {} null null null null {} null null null C1orf86 null null {} null null null null {} null null null C1orf87 InterPro UniProtKB {GO:0005509=GO_REF:0000002} Q8N0U7 Uncharacterized protein C1orf87 protein 20130413 {GO:0005509=IEA} calcium ion binding Human InterPro:IPR011992 C1orf94 IntAct UniProtKB {GO:0005515=PMID:23088713} Q6P1W5 Uncharacterized protein C1orf94 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:P09022 C1QA IntAct UniProtKB {GO:0005515=PMID:12960167, GO:0006956=Reactome:REACT_8024, GO:0005581=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0006958=Reactome:REACT_7956, GO:0007267=PMID:9461517, GO:0005576=Reactome:REACT_8002, GO:0005602=PMID:9461517} P02745 Complement C1q subcomponent subunit A protein 20130415 {GO:0005515=IPI, GO:0006956=TAS, GO:0005581=IEA, GO:0045087=TAS, GO:0006958=TAS, GO:0007267=TAS, GO:0005576=TAS, GO:0005602=TAS} cell-cell signaling, complement activation, complement activation, classical pathway, innate immune response collagen, complement component C1 complex, extracellular region protein binding Human UniProtKB:P02746 C1QB IntAct UniProtKB {GO:0005515=PMID:12960167, GO:0006956=Reactome:REACT_8024, GO:0048839=GO_REF:0000019, GO:0005581=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0006958=Reactome:REACT_7956, GO:0005576=Reactome:REACT_8002, GO:0005602=PMID:1706597, GO:0042803=GO_REF:0000019} P02746 Complement C1q subcomponent subunit B protein 20130415 {GO:0005515=IPI, GO:0006956=TAS, GO:0048839=IEA, GO:0005581=IEA, GO:0045087=TAS, GO:0006958=TAS, GO:0005576=TAS, GO:0005602=TAS, GO:0042803=IEA} complement activation, complement activation, classical pathway, innate immune response, inner ear development collagen, complement component C1 complex, extracellular region protein binding, protein homodimerization activity Human UniProtKB:P02745 C1QBP IntAct UniProtKB {GO:0008380=GO_REF:0000037, GO:0005515=PMID:22238231, GO:0050687=PMID:19164550, GO:0051897=PMID:16177118, GO:0030449=PMID:8195709, GO:0030984=PMID:8662673, GO:0048025=PMID:10022843, GO:0005886=Reactome:REACT_2239, GO:0070131=GO_REF:0000024, GO:0005634=PMID:15243141, GO:0003729=GO_REF:0000024, GO:0005615=GO_REF:0000019, GO:2000510=PMID:16140380, GO:0005829=PMID:15243141, GO:0005739=PMID:19164550, GO:0006955=PMID:8195709, GO:0005737=GO_REF:0000024, GO:1900026=PMID:11859136, GO:0005540=PMID:8567680, GO:0005759=GO_REF:0000039, GO:0039536=PMID:19164550, GO:0006958=GO_REF:0000037, GO:0005080=GO_REF:0000019, GO:0097177=GO_REF:0000024, GO:0032689=PMID:17881511, GO:1901165=PMID:20810993, GO:0006397=GO_REF:0000037, GO:0043065=PMID:15031724, GO:0042256=PMID:21536856, GO:0009986=PMID:17881511, GO:0003714=PMID:15243141, GO:0001849=PMID:8195709, GO:0005730=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0039534=PMID:19164550, GO:0000122=PMID:15243141, GO:0014065=PMID:16177118, GO:0006351=GO_REF:0000037, GO:0045785=PMID:20810993, GO:0031690=GO_REF:0000024, GO:0016020=PMID:8662673, GO:0007596=Reactome:REACT_2051, GO:0032695=PMID:17881511, GO:0007597=Reactome:REACT_326, GO:0045087=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0090023=PMID:9461517, GO:0008134=PMID:15243141} Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial protein 20130415 {GO:0008380=IEA, GO:0005515=IPI, GO:0050687=IMP, GO:0051897=IMP, GO:0030449=IDA, GO:0030984=IDA, GO:0048025=IDA, GO:0005886=TAS, GO:0070131=ISS, GO:0005634=IDA, GO:0003729=ISS, GO:0005615=IEA, GO:2000510=IMP, GO:0005829=IDA, GO:0005739=IDA, GO:0006955=TAS, GO:0005737=ISS, GO:1900026=IMP, GO:0005540=IDA, GO:0005759=IEA, GO:0039536=IDA, GO:0006958=IEA, GO:0005080=IEA, GO:0097177=ISS, GO:0032689=IDA, GO:1901165=IMP, GO:0006397=IEA, GO:0043065=IMP, GO:0042256=IMP, GO:0009986=IDA, GO:0003714=IDA, GO:0001849=IDA, GO:0005730=IEA, GO:0006915=IEA, GO:0039534=IDA, GO:0000122=IDA, GO:0014065=IMP, GO:0006351=IEA, GO:0045785=IMP, GO:0031690=ISS, GO:0016020=IDA, GO:0007596=TAS, GO:0032695=IDA, GO:0007597=TAS, GO:0045087=IEA, GO:0019048=IEA, GO:0090023=IDA, GO:0008134=IDA} RNA splicing, apoptotic process, blood coagulation, blood coagulation, intrinsic pathway, complement activation, classical pathway, immune response, innate immune response, mRNA processing, mature ribosome assembly, negative regulation of MDA-5 signaling pathway, negative regulation of RIG-I signaling pathway, negative regulation of defense response to virus, negative regulation of interferon-gamma production, negative regulation of interleukin-12 production, negative regulation of mRNA splicing, via spliceosome, negative regulation of transcription from RNA polymerase II promoter, phosphatidylinositol 3-kinase cascade, positive regulation of apoptotic process, positive regulation of cell adhesion, positive regulation of dendritic cell chemotaxis, positive regulation of mitochondrial translation, positive regulation of neutrophil chemotaxis, positive regulation of protein kinase B signaling cascade, positive regulation of substrate adhesion-dependent cell spreading, positive regulation of trophoblast cell migration, regulation of complement activation, transcription, DNA-dependent, virus-host interaction cell surface, cytoplasm, cytosol, extracellular space, membrane, mitochondrial matrix, mitochondrion, nucleolus, nucleus, plasma membrane adrenergic receptor binding, complement component C1q binding, hyaluronic acid binding, kininogen binding, mRNA binding, mitochondrial ribosome binding, protein binding, protein kinase C binding, transcription corepressor activity, transcription factor binding Human UniProtKB:O40955:PRO_0000240177 C1QC BHF-UCL UniProtKB {GO:0006956=Reactome:REACT_8024, GO:0006955=PMID:9777412, GO:0005581=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0006958=Reactome:REACT_7956, GO:0030853=PMID:10961870, GO:0005576=Reactome:REACT_8002, GO:0045650=PMID:10961870} P02747 Complement C1q subcomponent subunit C protein 20080926 {GO:0006956=TAS, GO:0006955=NAS, GO:0005581=IEA, GO:0045087=TAS, GO:0006958=TAS, GO:0030853=IDA, GO:0005576=TAS, GO:0045650=IDA} complement activation, complement activation, classical pathway, immune response, innate immune response, negative regulation of granulocyte differentiation, negative regulation of macrophage differentiation collagen, extracellular region Human C1QL1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000019, GO:0005581=GO_REF:0000037, GO:0007626=PMID:9878755, GO:0005575=GO_REF:0000015} O75973 C1q-related factor protein 20061026 {GO:0003674=ND, GO:0005737=IEA, GO:0005581=IEA, GO:0007626=NAS, GO:0005575=ND} locomotory behavior cellular_component, collagen, cytoplasm molecular_function Human C1QL3 ENSEMBL UniProtKB {GO:0005581=GO_REF:0000037, GO:0050807=GO_REF:0000019} Q5VWW1 Complement C1q-like protein 3 protein 20130413 {GO:0005581=IEA, GO:0050807=IEA} regulation of synapse organization collagen Human Ensembl:ENSMUSP00000056188 C1QTNF1 ENSEMBL UniProtKB {GO:0070208=GO_REF:0000019, GO:0051897=GO_REF:0000019, GO:0005581=GO_REF:0000037, GO:0051260=GO_REF:0000019, GO:0043410=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0010906=GO_REF:0000019} Q9BXJ1 Complement C1q tumor necrosis factor-related protein 1 protein 20130413 {GO:0070208=IEA, GO:0051897=IEA, GO:0005581=IEA, GO:0051260=IEA, GO:0043410=IEA, GO:0005615=IEA, GO:0010906=IEA} positive regulation of MAPK cascade, positive regulation of protein kinase B signaling cascade, protein heterotrimerization, protein homooligomerization, regulation of glucose metabolic process collagen, extracellular space Human Ensembl:ENSMUSP00000017590 C1QTNF5 UniProtKB UniProtKB {GO:0005581=GO_REF:0000037} Q9BXJ0 Complement C1q tumor necrosis factor-related protein 5 protein 20130413 {GO:0005581=IEA} collagen Human UniProtKB-KW:KW-0176 C1R IntAct UniProtKB {GO:0005515=PMID:12788922, GO:0006956=Reactome:REACT_8024, GO:0006955=PMID:737019, GO:0004252=Reactome:REACT_7978, GO:0045087=Reactome:REACT_6802, GO:0006958=Reactome:REACT_7956, GO:0005509=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0008236=PMID:2834284, GO:0005576=Reactome:REACT_8002} P00736 Complement C1r subcomponent protein 20130415 {GO:0005515=IPI, GO:0006956=TAS, GO:0006955=TAS, GO:0004252=EXP, GO:0045087=TAS, GO:0006958=TAS, GO:0005509=IEA, GO:0006508=IEA, GO:0008236=TAS, GO:0005576=TAS} complement activation, complement activation, classical pathway, immune response, innate immune response, proteolysis extracellular region calcium ion binding, protein binding, serine-type endopeptidase activity, serine-type peptidase activity Human UniProtKB:P09871 C1RL ENSEMBL UniProtKB {GO:0004252=GO_REF:0000002, GO:0045087=GO_REF:0000037, GO:0006958=GO_REF:0000037, GO:0006508=GO_REF:0000037, GO:0005615=GO_REF:0000019} Q9NZP8 Complement C1r subcomponent-like protein protein 20130413 {GO:0004252=IEA, GO:0045087=IEA, GO:0006958=IEA, GO:0006508=IEA, GO:0005615=IEA} complement activation, classical pathway, innate immune response, proteolysis extracellular space serine-type endopeptidase activity Human Ensembl:ENSMUSP00000042883 C1S IntAct UniProtKB {GO:0005515=PMID:12788922, GO:0006956=Reactome:REACT_8024, GO:0004252=PMID:11527969, GO:0045087=Reactome:REACT_6802, GO:0006958=Reactome:REACT_7956, GO:0005509=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0005576=Reactome:REACT_8002, GO:0042802=PMID:12788922} P09871 Complement C1s subcomponent protein 20130415 {GO:0005515=IPI, GO:0006956=TAS, GO:0004252=IDA, GO:0045087=TAS, GO:0006958=TAS, GO:0005509=IEA, GO:0006508=IEA, GO:0005576=TAS, GO:0042802=IPI} complement activation, complement activation, classical pathway, innate immune response, proteolysis extracellular region calcium ion binding, identical protein binding, protein binding, serine-type endopeptidase activity Human UniProtKB:P09871 C2 Reactome UniProtKB {GO:0030449=Reactome:REACT_118707, GO:0006956=Reactome:REACT_8024, GO:0004252=GO_REF:0000002, GO:0045087=Reactome:REACT_6802, GO:0006958=GO_REF:0000037, GO:0006508=GO_REF:0000037, GO:0005576=Reactome:REACT_118782, GO:0005615=PMID:8621452} P06681 Complement C2 protein 20101026 {GO:0030449=TAS, GO:0006956=TAS, GO:0004252=IEA, GO:0045087=TAS, GO:0006958=IEA, GO:0006508=IEA, GO:0005576=TAS, GO:0005615=TAS} complement activation, complement activation, classical pathway, innate immune response, proteolysis, regulation of complement activation extracellular region, extracellular space serine-type endopeptidase activity Human C20orf111 null null {} null null null null {} null null null C20orf194 null null {} null null null null {} null null null C20orf195 null null {} null null null null {} null null null C20orf196 null null {} null null null null {} null null null C20orf24 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q9BUV8 Uncharacterized protein C20orf24 protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human C20orf26 null null {} null null null null {} null null null C20orf27 BHF-UCL UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q9GZN8 UPF0687 protein C20orf27 protein 20120716 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human C20orf96 null null {} null null null null {} null null null C21orf2 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005737=PMID:21834987, GO:0005886=PMID:21834987, GO:0008360=PMID:21834987, GO:0007010=PMID:21834987, GO:0060271=GO_REF:0000019} O43822 Protein C21orf2 protein 20110926 {GO:0008150=ND, GO:0003674=ND, GO:0005737=IDA, GO:0005886=IDA, GO:0008360=IMP, GO:0007010=IMP, GO:0060271=IEA} biological_process, cilium morphogenesis, cytoskeleton organization, regulation of cell shape cytoplasm, plasma membrane molecular_function Human C21orf33 RefGenome UniProtKB {GO:0005739=GO_REF:0000033} P30042 ES1 protein homolog, mitochondrial protein 20110112 {GO:0005739=IBA} mitochondrion Human PANTHER:PTN000027433 C21orf58 null null {} null null null null {} null null null C21orf59 UniProtKB UniProtKB {GO:0005634=PMID:16780588, GO:0005829=PMID:16780588} P57076 Uncharacterized protein C21orf59 protein 20081007 {GO:0005634=IDA, GO:0005829=IDA} cytosol, nucleus Human C21orf91 null null {} null null null null {} null null null C22orf28 UniProtKB UniProtKB {GO:0006388=PMID:21311021, GO:0005737=GO_REF:0000039, GO:0007160=PMID:15163412, GO:0017166=PMID:15163412, GO:0034446=PMID:15163412, GO:0003972=PMID:21311021, GO:0001890=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0072669=PMID:21311021, GO:0046872=GO_REF:0000037} Q9Y3I0 tRNA-splicing ligase RtcB homolog protein 20110222 {GO:0006388=IDA, GO:0005737=IEA, GO:0007160=NAS, GO:0017166=IPI, GO:0034446=NAS, GO:0003972=IDA, GO:0001890=IEA, GO:0001701=IEA, GO:0005524=IEA, GO:0072669=IDA, GO:0046872=IEA} cell-matrix adhesion, in utero embryonic development, placenta development, substrate adhesion-dependent cell spreading, tRNA splicing, via endonucleolytic cleavage and ligation cytoplasm, tRNA-splicing ligase complex ATP binding, RNA ligase (ATP) activity, metal ion binding, vinculin binding Human C22orf39 null null {} null null null null {} null null null C22orf46 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} C9J442 Uncharacterized protein C22orf46 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 C2CD2 UniProtKB UniProtKB {GO:0005634=PMID:16780588, GO:0005576=GO_REF:0000039, GO:0005829=PMID:16780588} Q9Y426 C2 domain-containing protein 2 protein 20081007 {GO:0005634=IDA, GO:0005576=IEA, GO:0005829=IDA} cytosol, extracellular region, nucleus Human C2CD2L UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} O14523 C2 domain-containing protein 2-like protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND, GO:0016021=IEA} biological_process cellular_component, integral to membrane molecular_function Human C2CD3 UniProtKB UniProtKB {GO:0030162=GO_REF:0000019, GO:0021997=GO_REF:0000019, GO:0001947=GO_REF:0000019, GO:0042384=GO_REF:0000019, GO:0005813=PMID:21399614, GO:0016485=GO_REF:0000019, GO:0008589=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0021915=GO_REF:0000019, GO:0005932=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0042733=GO_REF:0000019} Q4AC94 C2 domain-containing protein 3 protein 20110517 {GO:0030162=IEA, GO:0021997=IEA, GO:0001947=IEA, GO:0042384=IEA, GO:0005813=IDA, GO:0016485=IEA, GO:0008589=IEA, GO:0007420=IEA, GO:0021915=IEA, GO:0005932=IEA, GO:0001701=IEA, GO:0042733=IEA} brain development, cilium assembly, embryonic digit morphogenesis, heart looping, in utero embryonic development, neural plate axis specification, neural tube development, protein processing, regulation of proteolysis, regulation of smoothened signaling pathway centrosome, microtubule basal body Human C2orf27B null null {} null null null null {} null null null C2orf42 null null {} null null null null {} null null null C2orf43 null null {} null null null null {} null null null C2orf44 null null {} null null null null {} null null null C2orf47 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039} Q8WWC4 Uncharacterized protein C2orf47, mitochondrial protein 20130413 {GO:0005739=IEA} mitochondrion Human UniProtKB-SubCell:SL-0173 C2orf49 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0048598=GO_REF:0000002, GO:0072669=PMID:21311021} Q9BVC5 Ashwin protein 20110222 {GO:0003674=ND, GO:0008150=ND, GO:0048598=IEA, GO:0072669=IDA} biological_process, embryonic morphogenesis tRNA-splicing ligase complex molecular_function Human C2orf50 null null {} null null null null {} null null null C2orf57 null null {} null null null null {} null null null C2orf62 null null {} null null null null {} null null null C2orf68 null null {} null null null null {} null null null C2orf73 null null {} null null null null {} null null null C2orf74 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} A8MZ97 Uncharacterized protein C2orf74 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C2orf76 null null {} null null null null {} null null null C2orf88 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039} Q9BSF0 Small membrane A-kinase anchor protein protein 20130413 {GO:0005886=IEA} plasma membrane Human UniProtKB-SubCell:SL-0039 C3 BHF-UCL UniProtKB {GO:0005515=PMID:16530040, GO:0030449=Reactome:REACT_118707, GO:0004866=GO_REF:0000002, GO:0005886=Reactome:REACT_118841, GO:0001970=GO_REF:0000019, GO:0005615=GO_REF:0000002, GO:0006957=Reactome:REACT_8001, GO:0006956=Reactome:REACT_8024, GO:0050766=GO_REF:0000019, GO:0006955=PMID:4097977, GO:0006954=GO_REF:0000037, GO:0006958=GO_REF:0000037, GO:0006631=GO_REF:0000037, GO:0001798=GO_REF:0000019, GO:0045745=PMID:15833747, GO:0005102=PMID:9164946, GO:0010884=PMID:9555951, GO:0005576=Reactome:REACT_118844, GO:0010866=PMID:10432298, GO:0010575=PMID:16452172, GO:0031715=PMID:15833747, GO:0045766=GO_REF:0000019, GO:0010828=PMID:15833747, GO:0007165=PMID:10085065, GO:0007186=PMID:9164946, GO:0045087=Reactome:REACT_6802, GO:0050776=Reactome:REACT_11152, GO:0001934=PMID:15833747} P01024 Complement C3 protein 20100104 {GO:0005515=IPI, GO:0030449=TAS, GO:0004866=IEA, GO:0005886=TAS, GO:0001970=IEA, GO:0005615=IEA, GO:0006957=TAS, GO:0006956=TAS, GO:0050766=IEA, GO:0006955=TAS, GO:0006954=IEA, GO:0006958=IEA, GO:0006631=IEA, GO:0001798=IEA, GO:0045745=IDA, GO:0005102=TAS, GO:0010884=IDA, GO:0005576=TAS, GO:0010866=IDA, GO:0010575=IDA, GO:0031715=IDA, GO:0045766=IEA, GO:0010828=IDA, GO:0007165=TAS, GO:0007186=TAS, GO:0045087=TAS, GO:0050776=TAS, GO:0001934=IDA} G-protein coupled receptor signaling pathway, complement activation, complement activation, alternative pathway, complement activation, classical pathway, fatty acid metabolic process, immune response, inflammatory response, innate immune response, positive regulation of G-protein coupled receptor protein signaling pathway, positive regulation of activation of membrane attack complex, positive regulation of angiogenesis, positive regulation of glucose transport, positive regulation of lipid storage, positive regulation of phagocytosis, positive regulation of protein phosphorylation, positive regulation of type IIa hypersensitivity, positive regulation vascular endothelial growth factor production, regulation of complement activation, regulation of immune response, regulation of triglyceride biosynthetic process, signal transduction extracellular region, extracellular space, plasma membrane C5L2 anaphylatoxin chemotactic receptor binding, endopeptidase inhibitor activity, protein binding, receptor binding Human C3AR1 Reactome UniProtKB {GO:0005886=Reactome:REACT_22289, GO:0004943=GO_REF:0000002, GO:0004930=PMID:10571060, GO:0008015=PMID:8765043, GO:0010575=GO_REF:0000019, GO:0007204=PMID:10571060, GO:0045766=GO_REF:0000019, GO:0004982=GO_REF:0000002, GO:0006954=PMID:8765043, GO:0007186=PMID:8898085, GO:0006935=GO_REF:0000037, GO:0004435=PMID:8765043, GO:0005887=PMID:8702752, GO:0010759=GO_REF:0000019, GO:0090023=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0004876=PMID:8765043} Q16581 C3a anaphylatoxin chemotactic receptor protein 20091026 {GO:0005886=TAS, GO:0004943=IEA, GO:0004930=IGI, GO:0008015=TAS, GO:0010575=IEA, GO:0007204=IGI, GO:0045766=IEA, GO:0004982=IEA, GO:0006954=TAS, GO:0007186=TAS, GO:0006935=IEA, GO:0004435=TAS, GO:0005887=TAS, GO:0010759=IEA, GO:0090023=IEA, GO:0016021=IEA, GO:0004876=TAS} G-protein coupled receptor signaling pathway, blood circulation, chemotaxis, elevation of cytosolic calcium ion concentration, inflammatory response, positive regulation of angiogenesis, positive regulation of macrophage chemotaxis, positive regulation of neutrophil chemotaxis, positive regulation vascular endothelial growth factor production integral to membrane, integral to plasma membrane, plasma membrane C3a anaphylatoxin receptor activity, G-protein coupled receptor activity, N-formyl peptide receptor activity, complement component C3a receptor activity, phosphatidylinositol phospholipase C activity Human C3orf17 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q6NW34 Uncharacterized protein C3orf17 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C3orf20 LIFEdb UniProtKB {GO:0005737=GO_REF:0000054, GO:0016021=GO_REF:0000037} Q8ND61 Uncharacterized protein C3orf20 protein 20100607 {GO:0005737=IDA, GO:0016021=IEA} cytoplasm, integral to membrane Human C3orf33 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0003676=GO_REF:0000002} Q6P1S2 Uncharacterized protein C3orf33 protein 20130413 {GO:0016021=IEA, GO:0003676=IEA} integral to membrane nucleic acid binding Human UniProtKB-KW:KW-0812 C3orf36 null null {} null null null null {} null null null C3orf37 null null {} null null null null {} null null null C3orf38 UniProtKB UniProtKB {GO:0006915=GO_REF:0000037} Q5JPI3 Uncharacterized protein C3orf38 protein 20130413 {GO:0006915=IEA} apoptotic process Human UniProtKB-KW:KW-0053 C3orf52 null null {} null null null null {} null null null C3orf62 null null {} null null null null {} null null null C4A Reactome UniProtKB {GO:0030449=Reactome:REACT_118707, GO:0006956=Reactome:REACT_8024, GO:0006954=GO_REF:0000037, GO:0005886=Reactome:REACT_118719, GO:0004866=GO_REF:0000002, GO:0045087=Reactome:REACT_6802, GO:0006958=GO_REF:0000037, GO:0005576=Reactome:REACT_118782, GO:0005615=GO_REF:0000002} P0C0L4 Complement C4-A protein 20101026 {GO:0030449=TAS, GO:0006956=TAS, GO:0006954=IEA, GO:0005886=TAS, GO:0004866=IEA, GO:0045087=TAS, GO:0006958=IEA, GO:0005576=TAS, GO:0005615=IEA} complement activation, complement activation, classical pathway, inflammatory response, innate immune response, regulation of complement activation extracellular region, extracellular space, plasma membrane endopeptidase inhibitor activity Human C4B Reactome UniProtKB {GO:0030449=Reactome:REACT_118707, GO:0006956=Reactome:REACT_8024, GO:0006954=GO_REF:0000037, GO:0005886=Reactome:REACT_118719, GO:0004866=GO_REF:0000002, GO:0045087=Reactome:REACT_6802, GO:0006958=GO_REF:0000037, GO:0005576=Reactome:REACT_118782, GO:0005615=GO_REF:0000002} P0C0L5 Complement C4-B protein 20101026 {GO:0030449=TAS, GO:0006956=TAS, GO:0006954=IEA, GO:0005886=TAS, GO:0004866=IEA, GO:0045087=TAS, GO:0006958=IEA, GO:0005576=TAS, GO:0005615=IEA} complement activation, complement activation, classical pathway, inflammatory response, innate immune response, regulation of complement activation extracellular region, extracellular space, plasma membrane endopeptidase inhibitor activity Human C4BPA HPA UniProtKB {GO:0005515=PMID:16330538, GO:0030449=Reactome:REACT_118707, GO:0005737=GO_REF:0000052, GO:0005886=Reactome:REACT_118836, GO:0045087=Reactome:REACT_6802, GO:0006958=GO_REF:0000037, GO:0005576=PMID:14718574} P04003 C4b-binding protein alpha chain protein 20101115 {GO:0005515=IPI, GO:0030449=TAS, GO:0005737=IDA, GO:0005886=TAS, GO:0045087=TAS, GO:0006958=IEA, GO:0005576=NAS} complement activation, classical pathway, innate immune response, regulation of complement activation cytoplasm, extracellular region, plasma membrane protein binding Human C4BPB Reactome UniProtKB {GO:0030449=Reactome:REACT_118707, GO:0005886=Reactome:REACT_118836, GO:0007596=PMID:8325877, GO:0045087=Reactome:REACT_6802, GO:0006958=GO_REF:0000037, GO:0005576=PMID:14718574} P20851 C4b-binding protein beta chain protein 20101026 {GO:0030449=TAS, GO:0005886=TAS, GO:0007596=TAS, GO:0045087=TAS, GO:0006958=IEA, GO:0005576=NAS} blood coagulation, complement activation, classical pathway, innate immune response, regulation of complement activation extracellular region, plasma membrane Human C4orf17 null null {} null null null null {} null null null C4orf21 InterPro UniProtKB {GO:0008270=GO_REF:0000002} I3L0G6 Uncharacterized protein C4orf21 protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR010666 C4orf22 null null {} null null null null {} null null null C4orf27 LIFEdb UniProtKB {GO:0005634=GO_REF:0000054} Q9NWY4 UPF0609 protein C4orf27 protein 20100607 {GO:0005634=IDA} nucleus Human C4orf29 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q0P651 Uncharacterized protein C4orf29 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 C4orf32 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8N8J7 Uncharacterized protein C4orf32 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C4orf36 null null {} null null null null {} null null null C4orf46 null null {} null null null null {} null null null C5 BHF-UCL UniProtKB {GO:0004866=GO_REF:0000002, GO:0005615=GO_REF:0000002, GO:0010760=PMID:14566334, GO:0006957=GO_REF:0000037, GO:0006956=Reactome:REACT_7972, GO:0000187=PMID:7649993, GO:0006954=PMID:8759757, GO:0050921=GO_REF:0000019, GO:0006935=GO_REF:0000019, GO:0005579=GO_REF:0000037, GO:0019835=GO_REF:0000037, GO:0006958=GO_REF:0000037, GO:0090197=PMID:14566334, GO:0008009=PMID:10820279, GO:0002523=GO_REF:0000019, GO:0006874=GO_REF:0000019, GO:0005102=PMID:9590258, GO:0006950=PMID:9590258, GO:0005576=Reactome:REACT_24998, GO:0006917=GO_REF:0000019, GO:0042593=GO_REF:0000019, GO:0031714=GO_REF:0000019, GO:0010700=GO_REF:0000019, GO:0010575=PMID:16452172, GO:0001701=GO_REF:0000019, GO:0045766=GO_REF:0000019, GO:0007186=PMID:8898085, GO:0045087=Reactome:REACT_6802, GO:0033602=GO_REF:0000019, GO:0007166=PMID:10820279} P01031 Complement C5 protein 20100104 {GO:0004866=IEA, GO:0005615=IEA, GO:0010760=IDA, GO:0006957=IEA, GO:0006956=TAS, GO:0000187=TAS, GO:0006954=TAS, GO:0050921=IEA, GO:0006935=IEA, GO:0005579=IEA, GO:0019835=IEA, GO:0006958=IEA, GO:0090197=IDA, GO:0008009=TAS, GO:0002523=IEA, GO:0006874=IEA, GO:0005102=TAS, GO:0006950=TAS, GO:0005576=TAS, GO:0006917=IEA, GO:0042593=IEA, GO:0031714=IEA, GO:0010700=IEA, GO:0010575=IDA, GO:0001701=IEA, GO:0045766=IEA, GO:0007186=TAS, GO:0045087=TAS, GO:0033602=IEA, GO:0007166=TAS} G-protein coupled receptor signaling pathway, activation of MAPK activity, cell surface receptor signaling pathway, cellular calcium ion homeostasis, chemotaxis, complement activation, complement activation, alternative pathway, complement activation, classical pathway, cytolysis, glucose homeostasis, in utero embryonic development, induction of apoptosis, inflammatory response, innate immune response, leukocyte migration involved in inflammatory response, negative regulation of dopamine secretion, negative regulation of macrophage chemotaxis, negative regulation of norepinephrine secretion, positive regulation of angiogenesis, positive regulation of chemokine secretion, positive regulation of chemotaxis, positive regulation vascular endothelial growth factor production, response to stress extracellular region, extracellular space, membrane attack complex C5a anaphylatoxin chemotactic receptor binding, chemokine activity, endopeptidase inhibitor activity, receptor binding Human C5AR1 GOC UniProtKB {GO:0021534=GO_REF:0000019, GO:0005886=Reactome:REACT_22289, GO:0004944=PMID:22496247, GO:0050830=GO_REF:0000019, GO:0007606=PMID:9590258, GO:0031100=GO_REF:0000019, GO:0001856=GO_REF:0000019, GO:0007202=PMID:7649993, GO:0007204=GO_REF:0000019, GO:0038178=PMID:22496247, GO:0016323=PMID:22960554, GO:0000187=PMID:7649993, GO:0043524=GO_REF:0000019, GO:0006955=PMID:9590258, GO:0006954=GO_REF:0000019, GO:0006935=PMID:10352266, GO:0032496=GO_REF:0000019, GO:0042789=PMID:22496247, GO:0070374=PMID:22496247, GO:0004878=PMID:22496247, GO:0050679=PMID:22496247, GO:0009986=GO_REF:0000019, GO:0030593=GO_REF:0000019, GO:0006915=GO_REF:0000019, GO:0045177=PMID:22496247, GO:0004982=GO_REF:0000002, GO:0007165=PMID:8702752, GO:0006968=PMID:8779720, GO:0005887=PMID:2007135, GO:0032494=GO_REF:0000019} P21730 C5a anaphylatoxin chemotactic receptor protein 20130413 {GO:0021534=IEA, GO:0005886=TAS, GO:0004944=IDA, GO:0050830=IEA, GO:0007606=TAS, GO:0031100=IEA, GO:0001856=IEA, GO:0007202=TAS, GO:0007204=IEA, GO:0038178=IDA, GO:0016323=IDA, GO:0000187=TAS, GO:0043524=IEA, GO:0006955=TAS, GO:0006954=IEA, GO:0006935=TAS, GO:0032496=IEA, GO:0042789=IDA, GO:0070374=IDA, GO:0004878=IDA, GO:0050679=IDA, GO:0009986=IEA, GO:0030593=IEA, GO:0006915=IEA, GO:0045177=IDA, GO:0004982=IEA, GO:0007165=TAS, GO:0006968=TAS, GO:0005887=TAS, GO:0032494=IEA} activation of MAPK activity, activation of phospholipase C activity, apoptotic process, cell proliferation in hindbrain, cellular defense response, chemotaxis, complement component C5a signaling pathway, defense response to Gram-positive bacterium, elevation of cytosolic calcium ion concentration, immune response, inflammatory response, mRNA transcription from RNA polymerase II promoter, negative regulation of neuron apoptotic process, neutrophil chemotaxis, organ regeneration, positive regulation of ERK1 and ERK2 cascade, positive regulation of epithelial cell proliferation, response to lipopolysaccharide, response to peptidoglycan, sensory perception of chemical stimulus, signal transduction apical part of cell, basolateral plasma membrane, cell surface, integral to plasma membrane, plasma membrane C5a anaphylatoxin receptor activity, N-formyl peptide receptor activity, complement component C5a binding, complement component C5a receptor activity Human C5orf15 null null {} null null null null {} null null null C5orf17 null null {} null null null null {} null null null C5orf22 null null {} null null null null {} null null null C5orf24 null null {} null null null null {} null null null C5orf28 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q0VDI3 Transmembrane protein C5orf28 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C5orf30 UniProtKB UniProtKB {GO:0005515=PMID:22085962, GO:0005737=PMID:22085962, GO:0060271=GO_REF:0000024, GO:0035869=PMID:22085962, GO:0015031=GO_REF:0000037} Q96GV9 UNC119-binding protein C5orf30 protein 20120113 {GO:0005515=IPI, GO:0005737=IDA, GO:0060271=ISS, GO:0035869=IDA, GO:0015031=IEA} cilium morphogenesis, protein transport ciliary transition zone, cytoplasm protein binding Human UniProtKB:Q13432 C5orf34 null null {} null null null null {} null null null C5orf42 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9H799 Uncharacterized protein C5orf42 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C5orf51 null null {} null null null null {} null null null C5orf54 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019} Q8IZ13 Transposon-derived Buster3 transposase-like protein protein 20130413 {GO:0005739=IEA} mitochondrion Human Ensembl:ENSMUSP00000044533 C5orf55 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q8N2X6 Uncharacterized protein C5orf55 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 C6 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0006956=PMID:2808363, GO:0005579=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0019835=GO_REF:0000037, GO:0006958=GO_REF:0000037, GO:0005576=Reactome:REACT_7988, GO:0001970=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0045766=GO_REF:0000019} P13671 Complement component C6 protein 20130415 {GO:0005515=IPI, GO:0006956=TAS, GO:0005579=IEA, GO:0045087=TAS, GO:0019835=IEA, GO:0006958=IEA, GO:0005576=TAS, GO:0001970=IEA, GO:0001701=IEA, GO:0045766=IEA} complement activation, complement activation, classical pathway, cytolysis, in utero embryonic development, innate immune response, positive regulation of activation of membrane attack complex, positive regulation of angiogenesis extracellular region, membrane attack complex protein binding Human UniProtKB:P16333 C6orf10 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q5SRN2 Uncharacterized protein C6orf10 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C6orf106 BHF-UCL UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q9H6K1 Uncharacterized protein C6orf106 protein 20110401 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human C6orf118 null null {} null null null null {} null null null C6orf136 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019} Q0P5T2 Uncharacterized protein C6orf136 protein 20130413 {GO:0005739=IEA} mitochondrion Human Ensembl:ENSMUSP00000116278 C6orf15 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005540=GO_REF:0000019, GO:0030198=GO_REF:0000019, GO:0043236=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0005614=GO_REF:0000019, GO:0001968=GO_REF:0000019, GO:0008201=GO_REF:0000019, GO:0070052=GO_REF:0000019} Q6UXA7 Uncharacterized protein C6orf15 protein 20061107 {GO:0003674=ND, GO:0008150=ND, GO:0005540=IEA, GO:0030198=IEA, GO:0043236=IEA, GO:0005575=ND, GO:0005614=IEA, GO:0001968=IEA, GO:0008201=IEA, GO:0070052=IEA} biological_process, extracellular matrix organization cellular_component, interstitial matrix collagen V binding, fibronectin binding, heparin binding, hyaluronic acid binding, laminin binding, molecular_function Human C6orf165 null null {} null null null null {} null null null C6orf170 null null {} null null null null {} null null null C6orf201 null null {} null null null null {} null null null C6orf203 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019} J3KQ88 Uncharacterized protein C6orf203 protein 20130413 {GO:0005739=IEA} mitochondrion Human Ensembl:ENSMUSP00000019932 C6orf211 null null {} null null null null {} null null null C6orf25 null null {} null null null null {} null null null C6orf47 null null {} null null null null {} null null null C6orf62 LIFEdb UniProtKB {GO:0005622=GO_REF:0000054, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015} Q9GZU0 Uncharacterized protein C6orf62 protein 20100607 {GO:0005622=IDA, GO:0003674=ND, GO:0008150=ND} biological_process intracellular molecular_function Human C6orf89 UniProtKB UniProtKB {GO:0005737=PMID:21857995, GO:0005886=PMID:21857995, GO:0000139=GO_REF:0000039, GO:0042060=PMID:21857995, GO:0005730=GO_REF:0000039, GO:0030496=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0045787=PMID:21857995, GO:0050673=PMID:21857995} Q6UWU4 Bombesin receptor-activated protein C6orf89 protein 20110831 {GO:0005737=IDA, GO:0005886=IDA, GO:0000139=IEA, GO:0042060=IDA, GO:0005730=IEA, GO:0030496=IEA, GO:0016021=IEA, GO:0045787=IDA, GO:0050673=IDA} epithelial cell proliferation, positive regulation of cell cycle, wound healing Golgi membrane, cytoplasm, integral to membrane, midbody, nucleolus, plasma membrane Human C7 Reactome UniProtKB {GO:0006957=GO_REF:0000037, GO:0006956=PMID:3335508, GO:0005579=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0019835=GO_REF:0000037, GO:0006958=GO_REF:0000037, GO:0005576=Reactome:REACT_7988} P10643 Complement component C7 protein 20060216 {GO:0006957=IEA, GO:0006956=TAS, GO:0005579=IEA, GO:0045087=TAS, GO:0019835=IEA, GO:0006958=IEA, GO:0005576=TAS} complement activation, complement activation, alternative pathway, complement activation, classical pathway, cytolysis, innate immune response extracellular region, membrane attack complex Human C7orf25 null null {} null null null null {} null null null C7orf26 null null {} null null null null {} null null null C7orf29 null null {} null null null null {} null null null C7orf31 null null {} null null null null {} null null null C7orf34 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q96L11 Uncharacterized protein C7orf34 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 C7orf41 null null {} null null null null {} null null null C7orf43 null null {} null null null null {} null null null C7orf50 null null {} null null null null {} null null null C7orf55 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019} Q96HJ9 UPF0562 protein C7orf55 protein 20130413 {GO:0005739=IEA} mitochondrion Human Ensembl:ENSMUSP00000019833 C8A Reactome UniProtKB {GO:0006957=GO_REF:0000037, GO:0006956=PMID:12413696, GO:0006955=PMID:6771072, GO:0005579=PMID:12413696, GO:0016020=PMID:2820471, GO:0045087=Reactome:REACT_6802, GO:0019835=GO_REF:0000037, GO:0006958=GO_REF:0000037, GO:0005576=Reactome:REACT_7988, GO:0005615=PMID:6771072} P07357 Complement component C8 alpha chain protein 20060216 {GO:0006957=IEA, GO:0006956=IDA, GO:0006955=TAS, GO:0005579=IDA, GO:0016020=TAS, GO:0045087=TAS, GO:0019835=IEA, GO:0006958=IEA, GO:0005576=TAS, GO:0005615=TAS} complement activation, complement activation, alternative pathway, complement activation, classical pathway, cytolysis, immune response, innate immune response extracellular region, extracellular space, membrane, membrane attack complex Human C8B Reactome UniProtKB {GO:0006957=GO_REF:0000037, GO:0006956=PMID:8098723, GO:0006955=PMID:8098723, GO:0016020=PMID:2820472, GO:0005579=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0006958=GO_REF:0000037, GO:0019835=GO_REF:0000019, GO:0005576=Reactome:REACT_7988, GO:0032403=GO_REF:0000019, GO:0005615=GO_REF:0000019} P07358 Complement component C8 beta chain protein 20060216 {GO:0006957=IEA, GO:0006956=TAS, GO:0006955=TAS, GO:0016020=TAS, GO:0005579=IEA, GO:0045087=TAS, GO:0006958=IEA, GO:0019835=IEA, GO:0005576=TAS, GO:0032403=IEA, GO:0005615=IEA} complement activation, complement activation, alternative pathway, complement activation, classical pathway, cytolysis, immune response, innate immune response extracellular region, extracellular space, membrane, membrane attack complex protein complex binding Human C8G UniProtKB UniProtKB {GO:0006957=GO_REF:0000037, GO:0001848=GO_REF:0000019, GO:0005579=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0019835=GO_REF:0000019, GO:0006958=GO_REF:0000037, GO:0005576=GO_REF:0000038, GO:0032403=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0019841=GO_REF:0000037} Q5SQ08 Complement component C8 gamma chain protein 20130413 {GO:0006957=IEA, GO:0001848=IEA, GO:0005579=IEA, GO:0045087=TAS, GO:0019835=IEA, GO:0006958=IEA, GO:0005576=IEA, GO:0032403=IEA, GO:0005615=IEA, GO:0019841=IEA} complement activation, alternative pathway, complement activation, classical pathway, cytolysis, innate immune response extracellular region, extracellular space, membrane attack complex complement binding, protein complex binding, retinol binding Human UniProtKB-KW:KW-0964 C8orf33 null null {} null null null null {} null null null C8orf34 InterPro UniProtKB {GO:0007165=GO_REF:0000002, GO:0008603=GO_REF:0000002} Q49A92 Uncharacterized protein C8orf34 protein 20130413 {GO:0007165=IEA, GO:0008603=IEA} signal transduction cAMP-dependent protein kinase regulator activity Human InterPro:IPR003117 C8orf4 UniProtKB UniProtKB {GO:0006915=GO_REF:0000037} Q9NR00 Uncharacterized protein C8orf4 protein 20130413 {GO:0006915=IEA} apoptotic process Human UniProtKB-KW:KW-0053 C8orf47 null null {} null null null null {} null null null C8orf48 IntAct UniProtKB {GO:0005515=PMID:19060904} Q96LL4 Uncharacterized protein C8orf48 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:Q99750 C8orf59 null null {} null null null null {} null null null C8orf76 null null {} null null null null {} null null null C9 HPA UniProtKB {GO:0006957=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005579=GO_REF:0000037, GO:0005887=PMID:2426252, GO:0045087=Reactome:REACT_6802, GO:0019836=PMID:2426252, GO:0019835=GO_REF:0000037, GO:0006958=GO_REF:0000037, GO:0005576=Reactome:REACT_7988} P02748 Complement component C9 protein 20120912 {GO:0006957=IEA, GO:0005737=IDA, GO:0005886=IDA, GO:0005579=IEA, GO:0005887=TAS, GO:0045087=TAS, GO:0019836=TAS, GO:0019835=IEA, GO:0006958=IEA, GO:0005576=TAS} complement activation, alternative pathway, complement activation, classical pathway, cytolysis, hemolysis by symbiont of host erythrocytes, innate immune response cytoplasm, extracellular region, integral to plasma membrane, membrane attack complex, plasma membrane Human C9orf106 null null {} null null null null {} null null null C9orf114 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q5T280 Uncharacterized protein C9orf114 protein 20081126 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human C9orf117 null null {} null null null null {} null null null C9orf123 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q96GE9 Transmembrane protein C9orf123 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 C9orf142 null null {} null null null null {} null null null C9orf156 UniProtKB UniProtKB {GO:0016787=GO_REF:0000037, GO:0019048=GO_REF:0000037} Q9BU70 Nef-associated protein 1 protein 20130413 {GO:0016787=IEA, GO:0019048=IEA} virus-host interaction hydrolase activity Human UniProtKB-KW:KW-0945 C9orf16 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q9BUW7 UPF0184 protein C9orf16 protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human C9orf163 null null {} null null null null {} null null null C9orf169 null null {} null null null null {} null null null C9orf24 null null {} null null null null {} null null null C9orf3 InterPro UniProtKB {GO:0019370=GO_REF:0000002, GO:0004177=GO_REF:0000038, GO:0006508=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0008237=GO_REF:0000002} H0YCM2 Protein C9orf3 protein 20130413 {GO:0019370=IEA, GO:0004177=IEA, GO:0006508=IEA, GO:0008270=IEA, GO:0008237=IEA} leukotriene biosynthetic process, proteolysis aminopeptidase activity, metallopeptidase activity, zinc ion binding Human InterPro:IPR015211 C9orf40 null null {} null null null null {} null null null C9orf41 null null {} null null null null {} null null null C9orf43 null null {} null null null null {} null null null C9orf50 null null {} null null null null {} null null null C9orf64 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q5T6V5 UPF0553 protein C9orf64 protein 20080604 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human C9orf72 UniProtKB UniProtKB {GO:0008219=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039} Q96LT7 Protein C9orf72 protein 20130413 {GO:0008219=IEA, GO:0005737=IEA, GO:0005634=IEA} cell death cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 C9orf78 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9NZ63 Uncharacterized protein C9orf78 protein 20100326 {GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA} cytoplasm, nucleolus, nucleus Human C9orf89 UniProtKB UniProtKB {GO:0050700=PMID:15637807, GO:0005634=PMID:15637807, GO:0043124=PMID:15637807, GO:0005829=PMID:15637807} Q96LW7 Bcl10-interacting CARD protein protein 20050818 {GO:0050700=NAS, GO:0005634=NAS, GO:0043124=NAS, GO:0005829=NAS} negative regulation of I-kappaB kinase/NF-kappaB cascade cytosol, nucleus CARD domain binding Human C9orf9 UniProtKB UniProtKB {GO:0005881=PMID:23264731} Q96E40 Uncharacterized protein C9orf9 protein 20130311 {GO:0005881=IDA} cytoplasmic microtubule Human C9orf91 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q5VZI3 Transmembrane protein C9orf91 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 CA1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0015701=Reactome:REACT_121380, GO:0008270=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0004089=GO_REF:0000003, GO:0006730=GO_REF:0000002, GO:0005829=Reactome:REACT_121371} P00915 Carbonic anhydrase 1 protein 20080818 {GO:0005737=IDA, GO:0005794=IDA, GO:0015701=TAS, GO:0008270=IEA, GO:0044281=TAS, GO:0004089=IEA, GO:0006730=IEA, GO:0005829=TAS} bicarbonate transport, one-carbon metabolic process, small molecule metabolic process Golgi apparatus, cytoplasm, cytosol carbonate dehydratase activity, zinc ion binding Human CA11 UniProtKB UniProtKB {GO:0016323=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0004089=PMID:9878252} O75493 Carbonic anhydrase-related protein 11 protein 20081212 {GO:0016323=IEA, GO:0005576=IEA, GO:0004089=TAS} basolateral plasma membrane, extracellular region carbonate dehydratase activity NOT Human CA12 Reactome UniProtKB {GO:0005886=Reactome:REACT_121310, GO:0015701=Reactome:REACT_121123, GO:0008270=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0004089=GO_REF:0000003, GO:0006730=GO_REF:0000002} O43570 Carbonic anhydrase 12 protein 20110807 {GO:0005886=TAS, GO:0015701=TAS, GO:0008270=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0004089=IEA, GO:0006730=IEA} bicarbonate transport, one-carbon metabolic process, small molecule metabolic process integral to membrane, plasma membrane carbonate dehydratase activity, zinc ion binding Human CA14 Reactome UniProtKB {GO:0005886=Reactome:REACT_121310, GO:0015701=Reactome:REACT_121123, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0004089=GO_REF:0000003, GO:0046872=GO_REF:0000037} Q9ULX7 Carbonic anhydrase 14 protein 20110807 {GO:0005886=TAS, GO:0015701=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0004089=IEA, GO:0046872=IEA} bicarbonate transport, small molecule metabolic process integral to membrane, plasma membrane carbonate dehydratase activity, metal ion binding Human CA2 HPA UniProtKB {GO:0030424=GO_REF:0000019, GO:0043627=GO_REF:0000019, GO:0001822=GO_REF:0000019, GO:0006950=GO_REF:0000019, GO:0045177=PMID:14675051, GO:0045672=GO_REF:0000019, GO:0032849=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0004089=GO_REF:0000003, GO:0015670=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0010043=GO_REF:0000019, GO:0046903=GO_REF:0000019, GO:0005829=Reactome:REACT_121371, GO:0005902=GO_REF:0000019, GO:0016323=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0045780=GO_REF:0000019, GO:0015701=Reactome:REACT_121380, GO:0042475=GO_REF:0000019, GO:0008270=PMID:3151020, GO:0006730=GO_REF:0000002, GO:0002009=GO_REF:0000019, GO:0009268=GO_REF:0000019} P00918 Carbonic anhydrase 2 protein 20101115 {GO:0030424=IEA, GO:0043627=IEA, GO:0001822=IEA, GO:0006950=IEA, GO:0045177=IDA, GO:0045672=IEA, GO:0032849=IEA, GO:0044281=TAS, GO:0004089=IEA, GO:0015670=IEA, GO:0005615=IEA, GO:0010043=IEA, GO:0046903=IEA, GO:0005829=TAS, GO:0005902=IEA, GO:0016323=IEA, GO:0005737=IDA, GO:0045780=IEA, GO:0015701=TAS, GO:0042475=IEA, GO:0008270=IDA, GO:0006730=IEA, GO:0002009=IEA, GO:0009268=IEA} bicarbonate transport, carbon dioxide transport, kidney development, morphogenesis of an epithelium, odontogenesis of dentin-containing tooth, one-carbon metabolic process, positive regulation of bone resorption, positive regulation of cellular pH reduction, positive regulation of osteoclast differentiation, response to estrogen stimulus, response to pH, response to stress, response to zinc ion, secretion, small molecule metabolic process apical part of cell, axon, basolateral plasma membrane, cytoplasm, cytosol, extracellular space, microvillus carbonate dehydratase activity, zinc ion binding Human CA3 Reactome UniProtKB {GO:0015701=Reactome:REACT_121123, GO:0008270=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0004089=GO_REF:0000003, GO:0006730=GO_REF:0000002, GO:0006979=GO_REF:0000019, GO:0005829=Reactome:REACT_120951, GO:0016151=GO_REF:0000019} P07451 Carbonic anhydrase 3 protein 20110807 {GO:0015701=TAS, GO:0008270=IEA, GO:0044281=TAS, GO:0004089=IEA, GO:0006730=IEA, GO:0006979=IEA, GO:0005829=TAS, GO:0016151=IEA} bicarbonate transport, one-carbon metabolic process, response to oxidative stress, small molecule metabolic process cytosol carbonate dehydratase activity, nickel cation binding, zinc ion binding Human CA4 Reactome UniProtKB {GO:0005515=PMID:15563508, GO:0005802=PMID:17409381, GO:0048471=PMID:17409381, GO:0005886=Reactome:REACT_121310, GO:0044281=Reactome:REACT_111217, GO:0048513=GO_REF:0000019, GO:0031225=GO_REF:0000002, GO:0031526=PMID:17409381, GO:0031362=PMID:17409381, GO:0016323=PMID:17409381, GO:0016324=PMID:17409381, GO:0044459=PMID:15563508, GO:0006730=GO_REF:0000002, GO:0030658=PMID:17409381, GO:0005791=PMID:17409381, GO:0005793=PMID:17409381, GO:0005794=PMID:17409381, GO:0009986=PMID:15563508, GO:0042493=GO_REF:0000019, GO:0004089=Reactome:REACT_120877, GO:0048545=GO_REF:0000019, GO:0042383=GO_REF:0000019, GO:0016529=GO_REF:0000019, GO:0016020=PMID:6811592, GO:0015701=Reactome:REACT_121380, GO:0008270=GO_REF:0000002, GO:0030667=PMID:17409381} P22748 Carbonic anhydrase 4 protein 20110807 {GO:0005515=IPI, GO:0005802=IDA, GO:0048471=IDA, GO:0005886=TAS, GO:0044281=TAS, GO:0048513=IEA, GO:0031225=IEA, GO:0031526=IDA, GO:0031362=IDA, GO:0016323=IDA, GO:0016324=IDA, GO:0044459=IDA, GO:0006730=IEA, GO:0030658=IDA, GO:0005791=IDA, GO:0005793=IDA, GO:0005794=IDA, GO:0009986=IDA, GO:0042493=IEA, GO:0004089=TAS, GO:0048545=IEA, GO:0042383=IEA, GO:0016529=IEA, GO:0016020=TAS, GO:0015701=TAS, GO:0008270=IEA, GO:0030667=IDA} bicarbonate transport, one-carbon metabolic process, organ development, response to drug, response to steroid hormone stimulus, small molecule metabolic process Golgi apparatus, anchored to external side of plasma membrane, anchored to membrane, apical plasma membrane, basolateral plasma membrane, brush border membrane, cell surface, endoplasmic reticulum-Golgi intermediate compartment, membrane, perinuclear region of cytoplasm, plasma membrane, plasma membrane part, rough endoplasmic reticulum, sarcolemma, sarcoplasmic reticulum, secretory granule membrane, trans-Golgi network, transport vesicle membrane carbonate dehydratase activity, protein binding, zinc ion binding Human CA5A Reactome UniProtKB {GO:0005739=PMID:8356065, GO:0005759=Reactome:REACT_120942, GO:0015701=Reactome:REACT_121123, GO:0008270=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0004089=GO_REF:0000003, GO:0006730=GO_REF:0000002} P35218 Carbonic anhydrase 5A, mitochondrial protein 20110807 {GO:0005739=TAS, GO:0005759=TAS, GO:0015701=TAS, GO:0008270=IEA, GO:0044281=TAS, GO:0004089=IEA, GO:0006730=IEA} bicarbonate transport, one-carbon metabolic process, small molecule metabolic process mitochondrial matrix, mitochondrion carbonate dehydratase activity, zinc ion binding Human CA5B Reactome UniProtKB {GO:0005739=PMID:10409679, GO:0005759=Reactome:REACT_120942, GO:0015701=Reactome:REACT_121123, GO:0008270=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0004089=GO_REF:0000003, GO:0006730=GO_REF:0000002} Q9Y2D0 Carbonic anhydrase 5B, mitochondrial protein 20110807 {GO:0005739=TAS, GO:0005759=TAS, GO:0015701=TAS, GO:0008270=IEA, GO:0044281=TAS, GO:0004089=IEA, GO:0006730=IEA} bicarbonate transport, one-carbon metabolic process, small molecule metabolic process mitochondrial matrix, mitochondrion carbonate dehydratase activity, zinc ion binding Human CA6 Reactome UniProtKB {GO:0005737=GO_REF:0000019, GO:0015701=Reactome:REACT_121123, GO:0005576=Reactome:REACT_120867, GO:0008270=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0004089=Reactome:REACT_120867, GO:0005615=GO_REF:0000019, GO:0006730=GO_REF:0000002} P23280 Carbonic anhydrase 6 protein 20110807 {GO:0005737=IEA, GO:0015701=TAS, GO:0005576=TAS, GO:0008270=IEA, GO:0044281=TAS, GO:0004089=TAS, GO:0005615=IEA, GO:0006730=IEA} bicarbonate transport, one-carbon metabolic process, small molecule metabolic process cytoplasm, extracellular region, extracellular space carbonate dehydratase activity, zinc ion binding Human CA8 ENSEMBL UniProtKB {GO:0005737=GO_REF:0000019, GO:0048015=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0004089=GO_REF:0000002, GO:0006730=GO_REF:0000002} P35219 Carbonic anhydrase-related protein protein 20130413 {GO:0005737=IEA, GO:0048015=IEA, GO:0008270=IEA, GO:0004089=IEA, GO:0006730=IEA} one-carbon metabolic process, phosphatidylinositol-mediated signaling cytoplasm carbonate dehydratase activity, zinc ion binding Human Ensembl:ENSMUSP00000063511 CA9 Reactome UniProtKB {GO:0005886=Reactome:REACT_121310, GO:0005730=GO_REF:0000039, GO:0071456=Reactome:REACT_121311, GO:0031528=GO_REF:0000039, GO:0061418=Reactome:REACT_120815, GO:0033554=Reactome:REACT_120956, GO:0004089=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0046903=GO_REF:0000019, GO:0015701=Reactome:REACT_121123, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0006730=GO_REF:0000002, GO:0002009=GO_REF:0000019} Q16790 Carbonic anhydrase 9 protein 20130301 {GO:0005886=TAS, GO:0005730=IEA, GO:0071456=TAS, GO:0031528=IEA, GO:0061418=TAS, GO:0033554=TAS, GO:0004089=IEA, GO:0044281=TAS, GO:0046903=IEA, GO:0015701=TAS, GO:0008270=IEA, GO:0016021=IEA, GO:0006730=IEA, GO:0002009=IEA} bicarbonate transport, cellular response to hypoxia, cellular response to stress, morphogenesis of an epithelium, one-carbon metabolic process, regulation of transcription from RNA polymerase II promoter in response to hypoxia, secretion, small molecule metabolic process integral to membrane, microvillus membrane, nucleolus, plasma membrane carbonate dehydratase activity, zinc ion binding Human CAB39 GOC UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005515=PMID:20562859, GO:0004674=PMID:19892943, GO:0045860=PMID:19892943, GO:0007050=Reactome:REACT_21387, GO:0030295=PMID:19892943, GO:0019900=PMID:19892943, GO:0005829=Reactome:REACT_21345} Q9Y376 Calcium-binding protein 39 protein 20130413 {GO:0008286=TAS, GO:0005515=IPI, GO:0004674=IDA, GO:0045860=IDA, GO:0007050=TAS, GO:0030295=IDA, GO:0019900=IPI, GO:0005829=TAS} cell cycle arrest, insulin receptor signaling pathway, positive regulation of protein kinase activity cytosol kinase binding, protein binding, protein kinase activator activity, protein serine/threonine kinase activity Human CAB39L Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0007050=Reactome:REACT_21387, GO:0005829=Reactome:REACT_21345} Q9H9S4 Calcium-binding protein 39-like protein 20130301 {GO:0008286=TAS, GO:0007050=TAS, GO:0005829=TAS} cell cycle arrest, insulin receptor signaling pathway cytosol Human CABIN1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0016235=GO_REF:0000052, GO:0004864=PMID:9655484, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0007166=PMID:9655484, GO:0016568=GO_REF:0000037} Q9Y6J0 Calcineurin-binding protein cabin-1 protein 20111111 {GO:0005737=IDA, GO:0016235=IDA, GO:0004864=NAS, GO:0005730=IDA, GO:0005634=IDA, GO:0007166=NAS, GO:0016568=IEA} cell surface receptor signaling pathway, chromatin modification aggresome, cytoplasm, nucleolus, nucleus protein phosphatase inhibitor activity Human CABLES1 Reactome UniProtKB {GO:0007049=GO_REF:0000037, GO:0007596=Reactome:REACT_604, GO:0051726=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0016538=GO_REF:0000002, GO:0051302=GO_REF:0000002, GO:0005829=PMID:17101133, GO:0007399=GO_REF:0000019, GO:0051301=GO_REF:0000037} Q8TDN4 CDK5 and ABL1 enzyme substrate 1 protein 20101112 {GO:0007049=IEA, GO:0007596=TAS, GO:0051726=IEA, GO:0005634=IEA, GO:0016538=IEA, GO:0051302=IEA, GO:0005829=IDA, GO:0007399=IEA, GO:0051301=IEA} blood coagulation, cell cycle, cell division, nervous system development, regulation of cell cycle, regulation of cell division cytosol, nucleus cyclin-dependent protein serine/threonine kinase regulator activity Human CABLES2 UniProtKB UniProtKB {GO:0007049=GO_REF:0000037, GO:0051726=GO_REF:0000002, GO:0016538=GO_REF:0000002, GO:0051302=GO_REF:0000002, GO:0051301=GO_REF:0000037} Q9BTV7 CDK5 and ABL1 enzyme substrate 2 protein 20130413 {GO:0007049=IEA, GO:0051726=IEA, GO:0016538=IEA, GO:0051302=IEA, GO:0051301=IEA} cell cycle, cell division, regulation of cell cycle, regulation of cell division cyclin-dependent protein serine/threonine kinase regulator activity Human UniProtKB-KW:KW-0132 CABP1 GOC UniProtKB {GO:0005515=PMID:15140941, GO:0004857=PMID:9920909, GO:0048471=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0005886=PMID:19338761, GO:0005509=GO_REF:0000002, GO:0014069=PMID:15140941, GO:0005634=GO_REF:0000019, GO:0043086=PMID:9920909, GO:0000139=PMID:19338761, GO:0045211=GO_REF:0000037, GO:0043025=GO_REF:0000019, GO:0042308=GO_REF:0000024, GO:0008139=GO_REF:0000024, GO:0005938=GO_REF:0000039, GO:0048306=PMID:15980432} Q9NZU7 Calcium-binding protein 1 protein 20130413 {GO:0005515=IPI, GO:0004857=TAS, GO:0048471=IEA, GO:0030054=IEA, GO:0005886=IDA, GO:0005509=IEA, GO:0014069=IDA, GO:0005634=IEA, GO:0043086=TAS, GO:0000139=IDA, GO:0045211=IEA, GO:0043025=IEA, GO:0042308=ISS, GO:0008139=ISS, GO:0005938=IEA, GO:0048306=IPI} negative regulation of catalytic activity, negative regulation of protein import into nucleus Golgi membrane, cell cortex, cell junction, neuronal cell body, nucleus, perinuclear region of cytoplasm, plasma membrane, postsynaptic density, postsynaptic membrane calcium ion binding, calcium-dependent protein binding, enzyme inhibitor activity, nuclear localization sequence binding, protein binding Human CABP2 MGI UniProtKB {GO:0007165=PMID:10625670, GO:0048471=GO_REF:0000039, GO:0005794=PMID:19338761, GO:0005886=PMID:19338761, GO:0005509=GO_REF:0000002} Q9NPB3 Calcium-binding protein 2 protein 20120319 {GO:0007165=TAS, GO:0048471=IEA, GO:0005794=IDA, GO:0005886=IDA, GO:0005509=IEA} signal transduction Golgi apparatus, perinuclear region of cytoplasm, plasma membrane calcium ion binding Human CABP4 MGI UniProtKB {GO:0007165=PMID:10625670, GO:0046549=GO_REF:0000019, GO:0060040=GO_REF:0000019, GO:0043195=PMID:15452577, GO:0005509=PMID:15452577, GO:0045202=PMID:16960802, GO:0005576=PMID:16960802, GO:0007602=GO_REF:0000019, GO:0007601=PMID:16960802, GO:0008594=GO_REF:0000019, GO:0005829=PMID:19338761} P57796 Calcium-binding protein 4 protein 20120604 {GO:0007165=NAS, GO:0046549=IEA, GO:0060040=IEA, GO:0043195=TAS, GO:0005509=TAS, GO:0045202=TAS, GO:0005576=NAS, GO:0007602=IEA, GO:0007601=IMP, GO:0008594=IEA, GO:0005829=IDA} photoreceptor cell morphogenesis, phototransduction, retinal bipolar neuron differentiation, retinal cone cell development, signal transduction, visual perception cytosol, extracellular region, synapse, terminal bouton calcium ion binding Human CABP5 HPA UniProtKB {GO:0007165=PMID:10625670, GO:0005737=GO_REF:0000052, GO:0015630=GO_REF:0000052, GO:0005509=PMID:10625670, GO:0005575=GO_REF:0000015, GO:0005829=PMID:19338761} Q9NP86 Calcium-binding protein 5 protein 20110516 {GO:0007165=NAS, GO:0005737=IDA, GO:0015630=IDA, GO:0005509=NAS, GO:0005575=ND, GO:0005829=IDA} signal transduction cellular_component, cytoplasm, cytosol, microtubule cytoskeleton calcium ion binding Human CABYR BHF-UCL UniProtKB {GO:0017124=PMID:11820818, GO:0008603=GO_REF:0000002, GO:0019901=GO_REF:0000019, GO:0046982=PMID:20731842, GO:0001539=PMID:18421703, GO:0019904=PMID:18421703, GO:0005509=PMID:11820818, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0007165=GO_REF:0000002, GO:0005737=PMID:11820818, GO:0035686=PMID:11820818, GO:0005856=GO_REF:0000039, GO:0048240=PMID:11820818} O75952 Calcium-binding tyrosine phosphorylation-regulated protein protein 20110222 {GO:0017124=NAS, GO:0008603=IEA, GO:0019901=IEA, GO:0046982=ISS, GO:0001539=IDA, GO:0019904=TAS, GO:0005509=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0007165=IEA, GO:0005737=IDA, GO:0035686=IDA, GO:0005856=IEA, GO:0048240=NAS} ciliary or flagellar motility, signal transduction, sperm capacitation cytoplasm, cytoskeleton, nucleolus, nucleus, sperm fibrous sheath SH3 domain binding, cAMP-dependent protein kinase regulator activity, calcium ion binding, protein domain specific binding, protein heterodimerization activity, protein kinase binding Human UniProtKB:Q9D424 CACHD1 UniProtKB UniProtKB {GO:0006816=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q5VU97 VWFA and cache domain-containing protein 1 protein 20130413 {GO:0006816=IEA, GO:0016021=IEA} calcium ion transport integral to membrane Human UniProtKB-KW:KW-0812 CACNA1A IntAct UniProtKB {GO:0005515=PMID:21078624, GO:0019905=PMID:8692999, GO:0008219=PMID:16595610, GO:0051899=Reactome:REACT_13606, GO:0005245=PMID:12451115, GO:0005886=Reactome:REACT_16913, GO:0007268=Reactome:REACT_13685, GO:0005634=PMID:16595610, GO:0044281=Reactome:REACT_111217, GO:0042995=PMID:16595610, GO:0005891=GO_REF:0000002, GO:0007204=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0005737=PMID:16595610, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0016021=PMID:16595610} O00555 Voltage-dependent P/Q-type calcium channel subunit alpha-1A protein 20130415 {GO:0005515=IPI, GO:0019905=IDA, GO:0008219=IDA, GO:0051899=TAS, GO:0005245=IDA, GO:0005886=TAS, GO:0007268=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0042995=IDA, GO:0005891=IEA, GO:0007204=ISS, GO:0046872=IEA, GO:0005737=IDA, GO:0006112=TAS, GO:0050796=TAS, GO:0016021=TAS} cell death, elevation of cytosolic calcium ion concentration, energy reserve metabolic process, membrane depolarization, regulation of insulin secretion, small molecule metabolic process, synaptic transmission cell projection, cytoplasm, integral to membrane, nucleus, plasma membrane, voltage-gated calcium channel complex metal ion binding, protein binding, syntaxin binding, voltage-gated calcium channel activity Human UniProtKB:Q9UHX1 CACNA1B InterPro UniProtKB {GO:0005515=PMID:20195357, GO:0051899=Reactome:REACT_13606, GO:0005886=Reactome:REACT_12594, GO:0005245=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0008016=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0008022=PMID:15728831, GO:0005891=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0007269=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0051924=GO_REF:0000019, GO:0006810=PMID:1321501, GO:0008217=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0048265=GO_REF:0000019} Q9HBH2 Calcium channel alpha12.2 subunit protein 20130413 {GO:0005515=IPI, GO:0051899=TAS, GO:0005886=TAS, GO:0005245=IEA, GO:0005509=IEA, GO:0008016=IEA, GO:0007268=TAS, GO:0008022=IPI, GO:0005891=IEA, GO:0005524=IEA, GO:0007269=IEA, GO:0030425=IEA, GO:0043025=IEA, GO:0051924=IEA, GO:0006810=TAS, GO:0008217=IEA, GO:0007626=IEA, GO:0048265=IEA} locomotory behavior, membrane depolarization, neurotransmitter secretion, regulation of blood pressure, regulation of calcium ion transport, regulation of heart contraction, response to pain, synaptic transmission, transport dendrite, neuronal cell body, plasma membrane, voltage-gated calcium channel complex ATP binding, calcium ion binding, protein C-terminus binding, protein binding, voltage-gated calcium channel activity Human InterPro:IPR005447 CACNA1C BHF-UCL UniProtKB {GO:0035585=PMID:11576544, GO:0005515=PMID:15140941, GO:0005516=PMID:15140941, GO:0030018=GO_REF:0000024, GO:0060402=PMID:19095005, GO:0005886=Reactome:REACT_16913, GO:0007268=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0007204=PMID:12130699, GO:0046872=GO_REF:0000037, GO:0019229=GO_REF:0000019, GO:0005737=PMID:11206130, GO:0007411=Reactome:REACT_18266, GO:0043198=GO_REF:0000019, GO:0017156=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0007628=GO_REF:0000019, GO:0030252=GO_REF:0000019, GO:0046620=GO_REF:0000019, GO:0005245=PMID:8392192, GO:0010881=PMID:11576544, GO:0008331=PMID:11576544, GO:0014069=PMID:14140941, GO:0042593=GO_REF:0000019, GO:0086064=PMID:11576544, GO:0005891=PMID:12130699, GO:0060083=GO_REF:0000019, GO:0002095=GO_REF:0000019, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0008542=GO_REF:0000019, GO:0008217=GO_REF:0000019, GO:0016021=PMID:8392192, GO:0030073=GO_REF:0000019} Q13936 Voltage-dependent L-type calcium channel subunit alpha-1C protein 20130213 {GO:0035585=TAS, GO:0005515=IPI, GO:0005516=IPI, GO:0030018=ISS, GO:0060402=TAS, GO:0005886=TAS, GO:0007268=IEA, GO:0044281=TAS, GO:0007204=IDA, GO:0046872=IEA, GO:0019229=IEA, GO:0005737=IDA, GO:0007411=TAS, GO:0043198=IEA, GO:0017156=IEA, GO:0043025=IEA, GO:0007628=IEA, GO:0030252=IEA, GO:0046620=IEA, GO:0005245=IDA, GO:0010881=TAS, GO:0008331=TAS, GO:0014069=IDA, GO:0042593=IEA, GO:0086064=TAS, GO:0005891=IDA, GO:0060083=IEA, GO:0002095=IEA, GO:0006112=TAS, GO:0050796=TAS, GO:0008542=IEA, GO:0008217=IEA, GO:0016021=IDA, GO:0030073=IEA} adult walking behavior, axon guidance, calcium ion transport into cytosol, calcium ion-dependent exocytosis, calcium-mediated signaling using extracellular calcium source, cell communication by electrical coupling involved in cardiac conduction, elevation of cytosolic calcium ion concentration, energy reserve metabolic process, glucose homeostasis, growth hormone secretion, insulin secretion, regulation of blood pressure, regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion, regulation of insulin secretion, regulation of organ growth, regulation of vasoconstriction, small molecule metabolic process, smooth muscle contraction involved in micturition, synaptic transmission, visual learning Z disc, caveolar macromolecular signaling complex, cytoplasm, dendritic shaft, integral to membrane, neuronal cell body, plasma membrane, postsynaptic density, voltage-gated calcium channel complex calmodulin binding, high voltage-gated calcium channel activity, metal ion binding, protein binding, voltage-gated calcium channel activity Human CACNA1D InterPro UniProtKB {GO:0086052=PMID:21131953, GO:0005245=GO_REF:0000002, GO:0005886=PMID:21859974, GO:0051928=PMID:1309651, GO:0007605=PMID:21131953, GO:0030506=PMID:21859974, GO:0044281=Reactome:REACT_111217, GO:0086091=PMID:21131953, GO:0005891=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0070509=PMID:1309651, GO:0060372=GO_REF:0000024, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0007411=Reactome:REACT_18266, GO:0086059=PMID:21131953, GO:0007188=GO_REF:0000024, GO:0006816=PMID:11160515, GO:0086012=PMID:21859974, GO:0086007=PMID:21859974} Q59GD8 Voltage-dependent L-type calcium channel subunit alpha-1D protein 20130413 {GO:0086052=IMP, GO:0005245=IEA, GO:0005886=ISS, GO:0051928=IDA, GO:0007605=IMP, GO:0030506=ISS, GO:0044281=TAS, GO:0086091=IMP, GO:0005891=IEA, GO:0046872=IEA, GO:0070509=IDA, GO:0060372=ISS, GO:0006112=TAS, GO:0050796=TAS, GO:0007411=TAS, GO:0086059=IMP, GO:0007188=ISS, GO:0006816=IDA, GO:0086012=IC, GO:0086007=IC} adenylate cyclase-modulating G-protein coupled receptor signaling pathway, axon guidance, calcium ion import, calcium ion transport, energy reserve metabolic process, membrane depolarization involved in regulation of cardiac muscle cell action potential, membrane repolarization involved in regulation of SA node cell action potential, positive regulation of calcium ion transport, regulation of atrial cardiac muscle cell membrane repolarization, regulation of heart rate by cardiac conduction, regulation of insulin secretion, sensory perception of sound, small molecule metabolic process plasma membrane, voltage-gated calcium channel complex ankyrin binding, metal ion binding, voltage-gated calcium channel activity, voltage-gated calcium channel activity involved in regulation of SA node cell action potential, voltage-gated calcium channel activity involved in regulation of cardiac muscle cell action potential Human InterPro:IPR002077|InterPro:IPR005452 CACNA1E Reactome UniProtKB {GO:0051899=Reactome:REACT_13606, GO:0005886=Reactome:REACT_16913, GO:0005245=PMID:8071363, GO:0005509=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0030317=GO_REF:0000019, GO:0042593=GO_REF:0000019, GO:0090273=GO_REF:0000019, GO:0019226=GO_REF:0000019, GO:0005891=GO_REF:0000002, GO:0019233=GO_REF:0000019, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0002027=GO_REF:0000019, GO:0008542=GO_REF:0000019, GO:0006810=PMID:8071363, GO:0001662=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0048266=GO_REF:0000019, GO:0061178=GO_REF:0000019} Q15878 Voltage-dependent R-type calcium channel subunit alpha-1E protein 20130213 {GO:0051899=TAS, GO:0005886=TAS, GO:0005245=IDA, GO:0005509=IEA, GO:0007268=TAS, GO:0044281=TAS, GO:0030317=IEA, GO:0042593=IEA, GO:0090273=IEA, GO:0019226=IEA, GO:0005891=IEA, GO:0019233=IEA, GO:0006112=TAS, GO:0050796=TAS, GO:0002027=IEA, GO:0008542=IEA, GO:0006810=TAS, GO:0001662=IEA, GO:0007626=IEA, GO:0048266=IEA, GO:0061178=IEA} behavioral fear response, behavioral response to pain, energy reserve metabolic process, glucose homeostasis, locomotory behavior, membrane depolarization, regulation of heart rate, regulation of insulin secretion, regulation of insulin secretion involved in cellular response to glucose stimulus, regulation of somatostatin secretion, sensory perception of pain, small molecule metabolic process, sperm motility, synaptic transmission, transmission of nerve impulse, transport, visual learning plasma membrane, voltage-gated calcium channel complex calcium ion binding, voltage-gated calcium channel activity Human CACNA1F UniProtKB UniProtKB {GO:0048813=GO_REF:0000019, GO:0005245=PMID:15897456, GO:0060041=GO_REF:0000019, GO:0050908=PMID:7571473, GO:0006874=GO_REF:0000019, GO:0016021=PMID:15897456, GO:0007409=GO_REF:0000019, GO:0005891=PMID:15897456, GO:0007601=PMID:9662400, GO:0046872=GO_REF:0000037} O60840 Voltage-dependent L-type calcium channel subunit alpha-1F protein 20070122 {GO:0048813=IEA, GO:0005245=IDA, GO:0060041=IEA, GO:0050908=IMP, GO:0006874=IEA, GO:0016021=IDA, GO:0007409=IEA, GO:0005891=IDA, GO:0007601=IMP, GO:0046872=IEA} axonogenesis, cellular calcium ion homeostasis, dendrite morphogenesis, detection of light stimulus involved in visual perception, retina development in camera-type eye, visual perception integral to membrane, voltage-gated calcium channel complex metal ion binding, voltage-gated calcium channel activity Human CACNA1G InterPro UniProtKB {GO:0005245=GO_REF:0000002, GO:0008332=PMID:21084288, GO:0007268=GO_REF:0000019, GO:0005891=GO_REF:0000002, GO:0010045=GO_REF:0000019, GO:0060371=GO_REF:0000019, GO:0070509=PMID:21084288, GO:0002027=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0097110=PMID:21084288, GO:0042391=PMID:21084288, GO:0006810=PMID:9495342, GO:0016021=GO_REF:0000038, GO:0005216=GO_REF:0000002} Q19R18 Voltage-dependent T-type calcium channel subunit alpha-1G protein 20130413 {GO:0005245=IEA, GO:0008332=IDA, GO:0007268=IEA, GO:0005891=IEA, GO:0010045=IEA, GO:0060371=IEA, GO:0070509=IDA, GO:0002027=IEA, GO:0007411=TAS, GO:0097110=IPI, GO:0042391=IDA, GO:0006810=TAS, GO:0016021=IEA, GO:0005216=IEA} axon guidance, calcium ion import, regulation of atrial cardiac muscle cell membrane depolarization, regulation of heart rate, regulation of membrane potential, response to nickel cation, synaptic transmission, transport integral to membrane, voltage-gated calcium channel complex ion channel activity, low voltage-gated calcium channel activity, scaffold protein binding, voltage-gated calcium channel activity Human InterPro:IPR005445 CACNA1H BHF-UCL UniProtKB {GO:0008332=PMID:21084288, GO:0008016=PMID:9670923, GO:0007520=PMID:10861024, GO:0005891=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0032870=PMID:19342457, GO:2000344=PMID:20394732, GO:0034651=PMID:19342457, GO:0042383=GO_REF:0000019, GO:0070509=PMID:21084288, GO:0007517=PMID:9670923, GO:0035865=PMID:19342457, GO:0006936=PMID:9670923, GO:0007411=Reactome:REACT_18266, GO:0005901=GO_REF:0000019, GO:0042391=PMID:21084288, GO:0097110=PMID:21084288, GO:0006810=PMID:9670923, GO:0032342=PMID:19342457, GO:0016021=PMID:21084288, GO:0005216=GO_REF:0000002} O95180 Voltage-dependent T-type calcium channel subunit alpha-1H protein 20120801 {GO:0008332=IDA, GO:0008016=TAS, GO:0007520=TAS, GO:0005891=IEA, GO:0046872=IEA, GO:0032870=IEP, GO:2000344=IMP, GO:0034651=IMP, GO:0042383=IEA, GO:0070509=IDA, GO:0007517=NAS, GO:0035865=IEP, GO:0006936=TAS, GO:0007411=TAS, GO:0005901=IEA, GO:0042391=IDA, GO:0097110=IPI, GO:0006810=TAS, GO:0032342=IMP, GO:0016021=IDA, GO:0005216=IEA} aldosterone biosynthetic process, axon guidance, calcium ion import, cellular response to hormone stimulus, cellular response to potassium ion, cortisol biosynthetic process, muscle contraction, muscle organ development, myoblast fusion, positive regulation of acrosome reaction, regulation of heart contraction, regulation of membrane potential, transport caveola, integral to membrane, sarcolemma, voltage-gated calcium channel complex ion channel activity, low voltage-gated calcium channel activity, metal ion binding, scaffold protein binding Human CACNA1I IntAct UniProtKB {GO:0005515=PMID:16740636, GO:0007165=PMID:10454147, GO:0005245=PMID:10454147, GO:0007411=Reactome:REACT_18266, GO:0008332=GO_REF:0000029, GO:0006810=PMID:10454147, GO:0006816=GO_REF:0000029, GO:0005891=GO_REF:0000029} Q9P0X4 Voltage-dependent T-type calcium channel subunit alpha-1I protein 20130415 {GO:0005515=IPI, GO:0007165=TAS, GO:0005245=TAS, GO:0007411=TAS, GO:0008332=NAS, GO:0006810=TAS, GO:0006816=NAS, GO:0005891=NAS} axon guidance, calcium ion transport, signal transduction, transport voltage-gated calcium channel complex low voltage-gated calcium channel activity, protein binding, voltage-gated calcium channel activity Human UniProtKB:Q96P56 CACNA1S Reactome UniProtKB {GO:0005886=PMID:11206130, GO:0005245=PMID:9852570, GO:0006941=GO_REF:0000019, GO:0030315=PMID:17204937, GO:0008331=PMID:9852570, GO:0007520=GO_REF:0000019, GO:0005891=PMID:9852570, GO:0046872=GO_REF:0000037, GO:0005737=PMID:11206130, GO:0001501=GO_REF:0000019, GO:0016529=GO_REF:0000019, GO:0006936=PMID:17418573, GO:0007411=Reactome:REACT_18266, GO:0007528=GO_REF:0000019, GO:0043501=GO_REF:0000019, GO:0002074=GO_REF:0000019, GO:0006816=PMID:9852570, GO:0007029=GO_REF:0000019, GO:0031674=PMID:11206130} Q13698 Voltage-dependent L-type calcium channel subunit alpha-1S protein 20130301 {GO:0005886=IDA, GO:0005245=IDA, GO:0006941=IEA, GO:0030315=IDA, GO:0008331=IDA, GO:0007520=IEA, GO:0005891=IDA, GO:0046872=IEA, GO:0005737=IDA, GO:0001501=IEA, GO:0016529=IEA, GO:0006936=IMP, GO:0007411=TAS, GO:0007528=IEA, GO:0043501=IEA, GO:0002074=IEA, GO:0006816=IDA, GO:0007029=IEA, GO:0031674=IDA} axon guidance, calcium ion transport, endoplasmic reticulum organization, extraocular skeletal muscle development, muscle contraction, myoblast fusion, neuromuscular junction development, skeletal muscle adaptation, skeletal system development, striated muscle contraction I band, T-tubule, cytoplasm, plasma membrane, sarcoplasmic reticulum, voltage-gated calcium channel complex high voltage-gated calcium channel activity, metal ion binding, voltage-gated calcium channel activity Human CACNA2D1 BHF-UCL UniProtKB {GO:0016529=GO_REF:0000019, GO:0005245=PMID:1309651, GO:0051924=PMID:1309651, GO:0030315=GO_REF:0000019, GO:0006816=PMID:1309651, GO:0005891=PMID:1309651, GO:0046872=GO_REF:0000037} P54289 Voltage-dependent calcium channel subunit alpha-2/delta-1 protein 20120917 {GO:0016529=IEA, GO:0005245=IDA, GO:0051924=IDA, GO:0030315=IEA, GO:0006816=IDA, GO:0005891=IDA, GO:0046872=IEA} calcium ion transport, regulation of calcium ion transport T-tubule, sarcoplasmic reticulum, voltage-gated calcium channel complex metal ion binding, voltage-gated calcium channel activity Human CACNA2D2 Reactome UniProtKB {GO:0006112=Reactome:REACT_1505, GO:0046622=GO_REF:0000019, GO:0050796=Reactome:REACT_18325, GO:0005886=Reactome:REACT_16913, GO:0005245=GO_REF:0000019, GO:0007528=GO_REF:0000019, GO:0040014=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0060024=GO_REF:0000019, GO:0005891=GO_REF:0000019, GO:0046872=GO_REF:0000037} Q9NY47 Voltage-dependent calcium channel subunit alpha-2/delta-2 protein 20130213 {GO:0006112=TAS, GO:0046622=IEA, GO:0050796=TAS, GO:0005886=TAS, GO:0005245=IEA, GO:0007528=IEA, GO:0040014=IEA, GO:0044281=TAS, GO:0060024=IEA, GO:0005891=IEA, GO:0046872=IEA} energy reserve metabolic process, neuromuscular junction development, positive regulation of organ growth, regulation of insulin secretion, regulation of multicellular organism growth, rhythmic synaptic transmission, small molecule metabolic process plasma membrane, voltage-gated calcium channel complex metal ion binding, voltage-gated calcium channel activity Human CACNA2D3 ENSEMBL UniProtKB {GO:0005245=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q8IZS8 Voltage-dependent calcium channel subunit alpha-2/delta-3 protein 20130413 {GO:0005245=IEA, GO:0016021=IEA, GO:0046872=IEA} integral to membrane metal ion binding, voltage-gated calcium channel activity Human Ensembl:ENSRNOP00000042602 CACNA2D4 UniProtKB UniProtKB {GO:0005262=GO_REF:0000037, GO:0005244=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q7Z3S7 Voltage-dependent calcium channel subunit alpha-2/delta-4 protein 20130413 {GO:0005262=IEA, GO:0005244=IEA, GO:0016021=IEA, GO:0046872=IEA} integral to membrane calcium channel activity, metal ion binding, voltage-gated ion channel activity Human UniProtKB-KW:KW-0107 CACNB1 Reactome UniProtKB {GO:0016529=GO_REF:0000019, GO:0005245=PMID:1385409, GO:0007411=Reactome:REACT_18266, GO:0006612=GO_REF:0000019, GO:0006810=PMID:1385409, GO:0030315=GO_REF:0000019, GO:0008331=GO_REF:0000019, GO:0005891=GO_REF:0000019} Q02641 Voltage-dependent L-type calcium channel subunit beta-1 protein 20130301 {GO:0016529=IEA, GO:0005245=TAS, GO:0007411=TAS, GO:0006612=IEA, GO:0006810=TAS, GO:0030315=IEA, GO:0008331=IEA, GO:0005891=IEA} axon guidance, protein targeting to membrane, transport T-tubule, sarcoplasmic reticulum, voltage-gated calcium channel complex high voltage-gated calcium channel activity, voltage-gated calcium channel activity Human CACNB2 BHF-UCL UniProtKB {GO:0005515=PMID:17525370, GO:0005262=PMID:9594024, GO:0005245=PMID:1309651, GO:0051928=PMID:1309651, GO:0007268=GO_REF:0000019, GO:0005891=PMID:1309651, GO:0042383=GO_REF:0000039, GO:0070509=PMID:1309651, GO:0005887=PMID:9594024, GO:0007528=PMID:8494331, GO:0007411=Reactome:REACT_18266, GO:0006810=PMID:9254841, GO:0006816=GO_REF:0000029, GO:0007601=GO_REF:0000019} Q08289 Voltage-dependent L-type calcium channel subunit beta-2 protein 20120917 {GO:0005515=IPI, GO:0005262=NAS, GO:0005245=IDA, GO:0051928=IDA, GO:0007268=IEA, GO:0005891=IDA, GO:0042383=IEA, GO:0070509=IDA, GO:0005887=NAS, GO:0007528=TAS, GO:0007411=TAS, GO:0006810=TAS, GO:0006816=NAS, GO:0007601=IEA} axon guidance, calcium ion import, calcium ion transport, neuromuscular junction development, positive regulation of calcium ion transport, synaptic transmission, transport, visual perception integral to plasma membrane, sarcolemma, voltage-gated calcium channel complex calcium channel activity, protein binding, voltage-gated calcium channel activity Human CACNB3 Reactome UniProtKB {GO:0050852=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0051899=Reactome:REACT_13606, GO:0016020=PMID:16525042, GO:0005245=PMID:11160515, GO:0007411=Reactome:REACT_18266, GO:0006810=PMID:8119293, GO:0007268=Reactome:REACT_13685, GO:0006816=PMID:11160515, GO:0005891=PMID:11160515, GO:0005829=Reactome:REACT_12594} P54284 Voltage-dependent L-type calcium channel subunit beta-3 protein 20130213 {GO:0050852=IEA, GO:0016324=IEA, GO:0051899=TAS, GO:0016020=IDA, GO:0005245=IDA, GO:0007411=TAS, GO:0006810=TAS, GO:0007268=TAS, GO:0006816=IDA, GO:0005891=IDA, GO:0005829=TAS} T cell receptor signaling pathway, axon guidance, calcium ion transport, membrane depolarization, synaptic transmission, transport apical plasma membrane, cytosol, membrane, voltage-gated calcium channel complex voltage-gated calcium channel activity Human CACNB4 Reactome UniProtKB {GO:0050852=GO_REF:0000019, GO:0051899=Reactome:REACT_13606, GO:0005245=PMID:16525042, GO:0046058=GO_REF:0000019, GO:0014051=GO_REF:0000019, GO:0006874=GO_REF:0000019, GO:0035249=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0007214=GO_REF:0000019, GO:0048538=GO_REF:0000019, GO:0048536=GO_REF:0000019, GO:0005891=PMID:16525042, GO:0019227=GO_REF:0000019, GO:0005829=Reactome:REACT_12594, GO:0048541=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0050908=GO_REF:0000019, GO:0007528=GO_REF:0000019, GO:0006810=PMID:9628818, GO:0007628=GO_REF:0000019, GO:0009898=PMID:16385006} O00305 Voltage-dependent L-type calcium channel subunit beta-4 protein 20130213 {GO:0050852=IEA, GO:0051899=TAS, GO:0005245=IDA, GO:0046058=IEA, GO:0014051=IEA, GO:0006874=IEA, GO:0035249=IEA, GO:0007268=TAS, GO:0007214=IEA, GO:0048538=IEA, GO:0048536=IEA, GO:0005891=IDA, GO:0019227=IEA, GO:0005829=TAS, GO:0048541=IEA, GO:0007411=TAS, GO:0050908=IEA, GO:0007528=IEA, GO:0006810=TAS, GO:0007628=IEA, GO:0009898=TAS} Peyer's patch development, T cell receptor signaling pathway, adult walking behavior, axon guidance, cAMP metabolic process, cellular calcium ion homeostasis, detection of light stimulus involved in visual perception, gamma-aminobutyric acid secretion, gamma-aminobutyric acid signaling pathway, membrane depolarization, neuromuscular junction development, neuronal action potential propagation, spleen development, synaptic transmission, synaptic transmission, glutamatergic, thymus development, transport cytosol, internal side of plasma membrane, voltage-gated calcium channel complex voltage-gated calcium channel activity Human CACNG2 Reactome UniProtKB {GO:0005515=PMID:20805473, GO:0051899=Reactome:REACT_13606, GO:0005245=GO_REF:0000019, GO:0005886=Reactome:REACT_18393, GO:2000311=GO_REF:0000024, GO:0007268=Reactome:REACT_13685, GO:0005891=GO_REF:0000002, GO:0030666=Reactome:REACT_18393, GO:0060081=GO_REF:0000019, GO:0035255=GO_REF:0000019, GO:0007528=GO_REF:0000019, GO:0032281=GO_REF:0000024, GO:0006810=PMID:10221464} Q9Y698 Voltage-dependent calcium channel gamma-2 subunit protein 20130213 {GO:0005515=IPI, GO:0051899=TAS, GO:0005245=IEA, GO:0005886=TAS, GO:2000311=ISS, GO:0007268=TAS, GO:0005891=IEA, GO:0030666=TAS, GO:0060081=IEA, GO:0035255=IEA, GO:0007528=IEA, GO:0032281=ISS, GO:0006810=TAS} membrane depolarization, membrane hyperpolarization, neuromuscular junction development, regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity, synaptic transmission, transport alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex, endocytic vesicle membrane, plasma membrane, voltage-gated calcium channel complex ionotropic glutamate receptor binding, protein binding, voltage-gated calcium channel activity Human CACNG3 Reactome UniProtKB {GO:0030666=Reactome:REACT_18393, GO:0005886=Reactome:REACT_18393, GO:0005245=PMID:10221464, GO:0032281=GO_REF:0000024, GO:2000311=GO_REF:0000024, GO:0007268=Reactome:REACT_13685, GO:0006816=PMID:10221464, GO:0005891=PMID:10221464} O60359 Voltage-dependent calcium channel gamma-3 subunit protein 20130213 {GO:0030666=TAS, GO:0005886=TAS, GO:0005245=NAS, GO:0032281=ISS, GO:2000311=ISS, GO:0007268=TAS, GO:0006816=NAS, GO:0005891=NAS} calcium ion transport, regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity, synaptic transmission alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex, endocytic vesicle membrane, plasma membrane, voltage-gated calcium channel complex voltage-gated calcium channel activity Human CACNG4 Reactome UniProtKB {GO:0030666=Reactome:REACT_18393, GO:0051899=Reactome:REACT_13606, GO:0005886=Reactome:REACT_18393, GO:0005245=GO_REF:0000002, GO:0005887=PMID:10613843, GO:0032281=GO_REF:0000024, GO:0006810=PMID:10613843, GO:2000311=PMID:21172611, GO:0007268=Reactome:REACT_13685, GO:0005891=GO_REF:0000002} Q9UBN1 Voltage-dependent calcium channel gamma-4 subunit protein 20130213 {GO:0030666=TAS, GO:0051899=TAS, GO:0005886=TAS, GO:0005245=IEA, GO:0005887=TAS, GO:0032281=ISS, GO:0006810=TAS, GO:2000311=IDA, GO:0007268=TAS, GO:0005891=IEA} membrane depolarization, regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity, synaptic transmission, transport alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex, endocytic vesicle membrane, integral to plasma membrane, plasma membrane, voltage-gated calcium channel complex voltage-gated calcium channel activity Human CACNG7 UniProtKB UniProtKB {GO:0005245=PMID:11170751, GO:0032281=GO_REF:0000024, GO:2000311=PMID:21172611, GO:0006816=PMID:11170751, GO:0005891=PMID:11170751} P62955 Voltage-dependent calcium channel gamma-7 subunit protein 20110331 {GO:0005245=NAS, GO:0032281=ISS, GO:2000311=IDA, GO:0006816=NAS, GO:0005891=NAS} calcium ion transport, regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex, voltage-gated calcium channel complex voltage-gated calcium channel activity Human CACYBP HPA UniProtKB {GO:0005515=PMID:16085652, GO:0043005=GO_REF:0000019, GO:0060416=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0045740=GO_REF:0000019, GO:0030877=PMID:16085652, GO:0044297=GO_REF:0000019, GO:0042803=PMID:16085652, GO:0005737=GO_REF:0000052, GO:0005641=GO_REF:0000019, GO:0060548=GO_REF:0000019, GO:0071277=GO_REF:0000019, GO:0055007=GO_REF:0000019} Q9HB71 Calcyclin-binding protein protein 20100326 {GO:0005515=IPI, GO:0043005=IEA, GO:0060416=IEA, GO:0007568=IEA, GO:0045740=IEA, GO:0030877=IDA, GO:0044297=IEA, GO:0042803=IPI, GO:0005737=IDA, GO:0005641=IEA, GO:0060548=IEA, GO:0071277=IEA, GO:0055007=IEA} aging, cardiac muscle cell differentiation, cellular response to calcium ion, negative regulation of cell death, positive regulation of DNA replication, response to growth hormone stimulus beta-catenin destruction complex, cell body, cytoplasm, neuron projection, nuclear envelope lumen protein binding, protein homodimerization activity Human CAD BHF-UCL UniProtKB {GO:0017144=GO_REF:0000024, GO:0016810=GO_REF:0000002, GO:0016812=GO_REF:0000002, GO:0031100=GO_REF:0000019, GO:0005634=PMID:15890648, GO:0042995=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0009790=GO_REF:0000019, GO:0014075=GO_REF:0000019, GO:0016363=PMID:9525610, GO:0046872=GO_REF:0000037, GO:0042802=GO_REF:0000024, GO:0005829=PMID:15890648, GO:0046777=GO_REF:0000024, GO:0046134=Reactome:REACT_21376, GO:0031000=GO_REF:0000019, GO:0070409=GO_REF:0000002, GO:0043195=GO_REF:0000024, GO:0018107=GO_REF:0000024, GO:0043025=GO_REF:0000024, GO:0006520=GO_REF:0000002, GO:0007565=GO_REF:0000019, GO:0044205=GO_REF:0000041, GO:0055086=Reactome:REACT_1698, GO:0004088=GO_REF:0000024, GO:0070335=GO_REF:0000024, GO:0033574=GO_REF:0000019, GO:0005524=GO_REF:0000024, GO:0035690=GO_REF:0000019, GO:0051414=GO_REF:0000019, GO:0006228=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0004070=GO_REF:0000024, GO:0004672=GO_REF:0000024, GO:0007595=GO_REF:0000019, GO:0071364=GO_REF:0000019, GO:0004151=GO_REF:0000024, GO:0006543=GO_REF:0000002, GO:0006207=GO_REF:0000024, GO:0019899=PMID:15326225, GO:0006206=Reactome:REACT_957, GO:0016743=GO_REF:0000002, GO:0016597=GO_REF:0000002, GO:0006541=GO_REF:0000024} P27708 CAD protein protein 20110624 {GO:0017144=ISS, GO:0016810=IEA, GO:0016812=IEA, GO:0031100=IEA, GO:0005634=IDA, GO:0042995=ISS, GO:0044281=TAS, GO:0009790=IEA, GO:0014075=IEA, GO:0016363=IDA, GO:0046872=IEA, GO:0042802=ISS, GO:0005829=IDA, GO:0046777=ISS, GO:0046134=TAS, GO:0031000=IEA, GO:0070409=IEA, GO:0043195=ISS, GO:0018107=ISS, GO:0043025=ISS, GO:0006520=IEA, GO:0007565=IEA, GO:0044205=IEA, GO:0055086=TAS, GO:0004088=ISS, GO:0070335=ISS, GO:0033574=IEA, GO:0005524=ISS, GO:0035690=IEA, GO:0051414=IEA, GO:0006228=IEA, GO:0043234=IEA, GO:0004070=ISS, GO:0004672=ISS, GO:0007595=IEA, GO:0071364=IEA, GO:0004151=ISS, GO:0006543=IEA, GO:0006207=ISS, GO:0019899=IPI, GO:0006206=TAS, GO:0016743=IEA, GO:0016597=IEA, GO:0006541=ISS} 'de novo' UMP biosynthetic process, 'de novo' pyrimidine nucleobase biosynthetic process, UTP biosynthetic process, carbamoyl phosphate biosynthetic process, cellular amino acid metabolic process, cellular response to drug, cellular response to epidermal growth factor stimulus, drug metabolic process, embryo development, female pregnancy, glutamine catabolic process, glutamine metabolic process, lactation, nucleobase-containing small molecule metabolic process, organ regeneration, peptidyl-threonine phosphorylation, protein autophosphorylation, pyrimidine nucleobase metabolic process, pyrimidine nucleoside biosynthetic process, response to amine stimulus, response to caffeine, response to cortisol stimulus, response to testosterone stimulus, small molecule metabolic process cell projection, cytosol, neuronal cell body, nuclear matrix, nucleus, protein complex, terminal bouton ATP binding, amino acid binding, aspartate binding, aspartate carbamoyltransferase activity, carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity, carboxyl- or carbamoyltransferase activity, dihydroorotase activity, enzyme binding, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides, identical protein binding, metal ion binding, protein kinase activity Human UniProtKB:D4A8A0 CADM1 Reactome UniProtKB {GO:0005515=PMID:12234973, GO:0030424=GO_REF:0000019, GO:0008037=PMID:15811952, GO:0005886=Reactome:REACT_19220, GO:0050715=PMID:15811952, GO:0007283=GO_REF:0000037, GO:0030425=GO_REF:0000019, GO:0042803=PMID:12826663, GO:0030154=GO_REF:0000037, GO:0016323=PMID:12826663, GO:0016338=GO_REF:0000019, GO:0051606=PMID:12826663, GO:0005911=PMID:12826663, GO:0042271=PMID:15811952, GO:0007156=PMID:12826663, GO:0050839=GO_REF:0000019, GO:0007157=PMID:12826663, GO:0034329=Reactome:REACT_20676, GO:0005102=PMID:15811952, GO:0006915=GO_REF:0000037, GO:0008022=PMID:12826663, GO:0030165=PMID:12826663, GO:0007416=GO_REF:0000019, GO:0045216=Reactome:REACT_19331, GO:0009826=GO_REF:0000019, GO:0008021=GO_REF:0000019, GO:0001889=GO_REF:0000019, GO:0001913=PMID:15811952, GO:0007420=GO_REF:0000019, GO:0045954=PMID:15811952, GO:0050798=PMID:15811952, GO:0016021=GO_REF:0000037, GO:0034332=Reactome:REACT_19195} Q9BY67 Cell adhesion molecule 1 protein 20090512 {GO:0005515=IPI, GO:0030424=IEA, GO:0008037=IDA, GO:0005886=TAS, GO:0050715=IDA, GO:0007283=IEA, GO:0030425=IEA, GO:0042803=ISS, GO:0030154=IEA, GO:0016323=ISS, GO:0016338=IEA, GO:0051606=ISS, GO:0005911=ISS, GO:0042271=IDA, GO:0007156=ISS, GO:0050839=IEA, GO:0007157=ISS, GO:0034329=TAS, GO:0005102=IPI, GO:0006915=IEA, GO:0008022=ISS, GO:0030165=ISS, GO:0007416=IEA, GO:0045216=TAS, GO:0009826=IEA, GO:0008021=IEA, GO:0001889=IEA, GO:0001913=IDA, GO:0007420=IEA, GO:0045954=IDA, GO:0050798=IDA, GO:0016021=IEA, GO:0034332=TAS} T cell mediated cytotoxicity, activated T cell proliferation, adherens junction organization, apoptotic process, brain development, calcium-independent cell-cell adhesion, cell differentiation, cell junction assembly, cell recognition, cell-cell junction organization, detection of stimulus, heterophilic cell-cell adhesion, homophilic cell adhesion, liver development, positive regulation of cytokine secretion, positive regulation of natural killer cell mediated cytotoxicity, spermatogenesis, susceptibility to natural killer cell mediated cytotoxicity, synapse assembly, unidimensional cell growth axon, basolateral plasma membrane, cell-cell junction, dendrite, integral to membrane, plasma membrane, synaptic vesicle PDZ domain binding, cell adhesion molecule binding, protein C-terminus binding, protein binding, protein homodimerization activity, receptor binding Human CADM3 Reactome UniProtKB {GO:0008104=GO_REF:0000019, GO:0005886=Reactome:REACT_19267, GO:0005911=PMID:12826663, GO:0034329=Reactome:REACT_20676, GO:0016021=GO_REF:0000037, GO:0007156=PMID:12826663, GO:0045216=Reactome:REACT_19331, GO:0042803=PMID:12826663, GO:0007157=PMID:12826663, GO:0034332=Reactome:REACT_19195} Q8N126 Cell adhesion molecule 3 protein 20090512 {GO:0008104=IEA, GO:0005886=TAS, GO:0005911=ISS, GO:0034329=TAS, GO:0016021=IEA, GO:0007156=ISS, GO:0045216=TAS, GO:0042803=ISS, GO:0007157=ISS, GO:0034332=TAS} adherens junction organization, cell junction assembly, cell-cell junction organization, heterophilic cell-cell adhesion, homophilic cell adhesion, protein localization cell-cell junction, integral to membrane, plasma membrane protein homodimerization activity Human CADM4 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037} Q8NFZ8 Cell adhesion molecule 4 protein 20130413 {GO:0016021=IEA, GO:0007155=IEA} cell adhesion integral to membrane Human UniProtKB-KW:KW-0812 CADPS PINC UniProtKB {GO:0005515=PMID:17984325, GO:0050432=GO_REF:0000019, GO:0016050=GO_REF:0000019, GO:0016082=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005543=GO_REF:0000002, GO:0045202=GO_REF:0000039, GO:0006887=PMID:1516133, GO:0015031=GO_REF:0000037, GO:0030659=GO_REF:0000039, GO:0046872=GO_REF:0000037, GO:0005829=PMID:1516133} Q9ULU8 Calcium-dependent secretion activator 1 protein 20061106 {GO:0005515=IPI, GO:0050432=IEA, GO:0016050=IEA, GO:0016082=IEA, GO:0030054=IEA, GO:0005543=IEA, GO:0045202=IEA, GO:0006887=TAS, GO:0015031=IEA, GO:0030659=IEA, GO:0046872=IEA, GO:0005829=TAS} catecholamine secretion, exocytosis, protein transport, synaptic vesicle priming, vesicle organization cell junction, cytoplasmic vesicle membrane, cytosol, synapse metal ion binding, phospholipid binding, protein binding Human CADPS2 UniProtKB UniProtKB {GO:0045921=GO_REF:0000019, GO:0042734=GO_REF:0000019, GO:0016082=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005543=GO_REF:0000002, GO:0045211=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0030659=GO_REF:0000039, GO:0046872=GO_REF:0000037} Q86UW7 Calcium-dependent secretion activator 2 protein 20130413 {GO:0045921=IEA, GO:0042734=IEA, GO:0016082=IEA, GO:0030054=IEA, GO:0005543=IEA, GO:0045211=IEA, GO:0015031=IEA, GO:0030659=IEA, GO:0046872=IEA} positive regulation of exocytosis, protein transport, synaptic vesicle priming cell junction, cytoplasmic vesicle membrane, postsynaptic membrane, presynaptic membrane metal ion binding, phospholipid binding Human UniProtKB-SubCell:SL-0089 CALB1 BHF-UCL UniProtKB {GO:0005515=PMID:20098747, GO:0030424=GO_REF:0000024, GO:0071310=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0035502=GO_REF:0000019, GO:0005634=PMID:16928804, GO:0010842=GO_REF:0000019, GO:0072205=GO_REF:0000019, GO:0072221=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0048167=GO_REF:0000019, GO:0072286=GO_REF:0000019, GO:0007611=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0005499=GO_REF:0000037, GO:0007626=GO_REF:0000019} P05937 Calbindin protein 20120607 {GO:0005515=IPI, GO:0030424=ISS, GO:0071310=IEA, GO:0005509=IEA, GO:0035502=IEA, GO:0005634=IDA, GO:0010842=IEA, GO:0072205=IEA, GO:0072221=IEA, GO:0030425=IEA, GO:0005829=IEA, GO:0048167=IEA, GO:0072286=IEA, GO:0007611=IEA, GO:0043025=IEA, GO:0005499=IEA, GO:0007626=IEA} cellular response to organic substance, learning or memory, locomotory behavior, metanephric collecting duct development, metanephric connecting tubule development, metanephric distal convoluted tubule development, metanephric part of ureteric bud development, regulation of synaptic plasticity, retina layer formation axon, cytosol, dendrite, neuronal cell body, nucleus calcium ion binding, protein binding, vitamin D binding Human UniProtKB:P07171 CALB2 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005509=GO_REF:0000002, GO:0005921=GO_REF:0000019} P22676 Calretinin protein 20101115 {GO:0005737=IDA, GO:0005509=IEA, GO:0005921=IEA} cytoplasm, gap junction calcium ion binding Human CALCA Reactome UniProtKB {GO:0005515=PMID:9620797, GO:0009408=GO_REF:0000019, GO:0010523=PMID:16014619, GO:0005615=PMID:2408883, GO:0032403=PMID:14722252, GO:0032757=PMID:16904178, GO:0001984=GO_REF:0000019, GO:0007218=GO_REF:0000019, GO:0051482=PMID:9685362, GO:0043025=GO_REF:0000019, GO:0001944=PMID:17267696, GO:0007566=PMID:17983652, GO:0007568=GO_REF:0000019, GO:0045651=PMID:10822112, GO:0005179=GO_REF:0000037, GO:0002027=GO_REF:0000019, GO:0043542=PMID:17267696, GO:0007189=GO_REF:0000019, GO:0045892=PMID:11014233, GO:0007631=GO_REF:0000019, GO:0032730=PMID:16904178, GO:0030819=PMID:14722252, GO:0007267=PMID:2408883, GO:0005634=GO_REF:0000019, GO:0045778=GO_REF:0000019, GO:0007204=PMID:17983652, GO:0045779=PMID:10822112, GO:0032147=PMID:17983652, GO:0007190=PMID:16014619, GO:0005737=PMID:17267696, GO:0030279=GO_REF:0000019, GO:0006954=GO_REF:0000019, GO:0045986=GO_REF:0000019, GO:0043195=GO_REF:0000019, GO:0042311=GO_REF:0000002, GO:0045909=PMID:3266556, GO:0007159=PMID:1326102, GO:0050965=GO_REF:0000019, GO:0031645=GO_REF:0000019, GO:0051480=PMID:9685362, GO:0050727=GO_REF:0000019, GO:0005102=PMID:16014619, GO:0031716=PMID:8940110, GO:0005576=Reactome:REACT_22268, GO:0045762=PMID:8078488, GO:0045671=PMID:10822112, GO:0002548=PMID:15248232, GO:0001935=PMID:17267696, GO:0008217=PMID:1318039, GO:0048265=GO_REF:0000019} P06881 Calcitonin gene-related peptide 1 protein 20090507 {GO:0005515=IPI, GO:0009408=IEA, GO:0010523=IDA, GO:0005615=IDA, GO:0032403=IDA, GO:0032757=IDA, GO:0001984=IEA, GO:0007218=IEA, GO:0051482=IDA, GO:0043025=IEA, GO:0001944=IDA, GO:0007566=IDA, GO:0007568=IEA, GO:0045651=IDA, GO:0005179=IEA, GO:0002027=IEA, GO:0043542=IDA, GO:0007189=IEA, GO:0045892=IDA, GO:0007631=IEA, GO:0032730=IDA, GO:0030819=IDA, GO:0007267=TAS, GO:0005634=IEA, GO:0045778=IEA, GO:0007204=IDA, GO:0045779=IDA, GO:0032147=IDA, GO:0007190=IDA, GO:0005737=IDA, GO:0030279=IEA, GO:0006954=IEA, GO:0045986=IEA, GO:0043195=IEA, GO:0042311=IEA, GO:0045909=IDA, GO:0007159=IDA, GO:0050965=IEA, GO:0031645=IEA, GO:0051480=IDA, GO:0050727=IEA, GO:0005102=IDA, GO:0031716=IPI, GO:0005576=TAS, GO:0045762=IDA, GO:0045671=IDA, GO:0002548=IDA, GO:0001935=IDA, GO:0008217=NAS, GO:0048265=IEA} activation of adenylate cyclase activity, activation of protein kinase activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, aging, cell-cell signaling, cytosolic calcium ion homeostasis, detection of temperature stimulus involved in sensory perception of pain, elevation of cytosolic calcium ion concentration, elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway, embryo implantation, endothelial cell migration, endothelial cell proliferation, feeding behavior, inflammatory response, leukocyte cell-cell adhesion, monocyte chemotaxis, negative regulation of bone resorption, negative regulation of calcium ion transport into cytosol, negative regulation of neurological system process, negative regulation of ossification, negative regulation of osteoclast differentiation, negative regulation of smooth muscle contraction, negative regulation of transcription, DNA-dependent, neuropeptide signaling pathway, positive regulation of adenylate cyclase activity, positive regulation of cAMP biosynthetic process, positive regulation of interleukin-1 alpha production, positive regulation of interleukin-8 production, positive regulation of macrophage differentiation, positive regulation of ossification, positive regulation of vasodilation, regulation of blood pressure, regulation of heart rate, regulation of inflammatory response, response to heat, response to pain, vasculature development, vasodilation, vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure cytoplasm, extracellular region, extracellular space, neuronal cell body, nucleus, terminal bouton calcitonin receptor binding, hormone activity, protein binding, protein complex binding, receptor binding Human CALCOCO1 HPA UniProtKB {GO:0003712=PMID:16344550, GO:0005515=PMID:16344550, GO:0000790=GO_REF:0000019, GO:0008013=PMID:16344550, GO:0044212=PMID:16344550, GO:0003713=GO_REF:0000024, GO:0005634=GO_REF:0000054, GO:0008022=PMID:16344550, GO:0006351=GO_REF:0000024, GO:0043231=GO_REF:0000052, GO:0043565=PMID:16344550, GO:0007165=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0030374=PMID:16344550, GO:0030518=GO_REF:0000024, GO:0003682=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0016055=GO_REF:0000037, GO:0045893=PMID:16344550, GO:0070016=PMID:16344550} Q9P1Z2 Calcium-binding and coiled-coil domain-containing protein 1 protein 20111111 {GO:0003712=IDA, GO:0005515=IPI, GO:0000790=IEA, GO:0008013=IPI, GO:0044212=IDA, GO:0003713=ISS, GO:0005634=IDA, GO:0008022=IPI, GO:0006351=ISS, GO:0043231=IDA, GO:0043565=IDA, GO:0007165=ISS, GO:0005737=IDA, GO:0030374=IDA, GO:0030518=ISS, GO:0003682=IEA, GO:0045944=IEA, GO:0016055=IEA, GO:0045893=IMP, GO:0070016=IPI} Wnt receptor signaling pathway, intracellular steroid hormone receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, signal transduction, transcription, DNA-dependent cytoplasm, intracellular membrane-bounded organelle, nuclear chromatin, nucleus armadillo repeat domain binding, beta-catenin binding, chromatin binding, ligand-dependent nuclear receptor transcription coactivator activity, protein C-terminus binding, protein binding, sequence-specific DNA binding, transcription coactivator activity, transcription cofactor activity, transcription regulatory region DNA binding Human CALCOCO2 HPA UniProtKB {GO:0005515=PMID:21903422, GO:0048471=PMID:9230084, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0016032=PMID:7540613, GO:0005634=GO_REF:0000052, GO:0034341=PMID:9230084, GO:0005856=GO_REF:0000039, GO:0042803=PMID:9230084, GO:0043231=GO_REF:0000052} Q13137 Calcium-binding and coiled-coil domain-containing protein 2 protein 20101115 {GO:0005515=IPI, GO:0048471=IDA, GO:0005737=IDA, GO:0005794=IEA, GO:0005730=IDA, GO:0016032=TAS, GO:0005634=IDA, GO:0034341=IDA, GO:0005856=IEA, GO:0042803=IPI, GO:0043231=IDA} response to interferon-gamma, viral reproduction Golgi apparatus, cytoplasm, cytoskeleton, intracellular membrane-bounded organelle, nucleolus, nucleus, perinuclear region of cytoplasm protein binding, protein homodimerization activity Human CALCR Reactome UniProtKB {GO:0005515=PMID:7588285, GO:0004948=GO_REF:0000002, GO:0030424=GO_REF:0000019, GO:0032841=PMID:8078488, GO:0043488=GO_REF:0000019, GO:0005886=Reactome:REACT_22268, GO:0001669=GO_REF:0000019, GO:0030819=PMID:14722252, GO:0030316=GO_REF:0000019, GO:0051384=PMID:11250927, GO:0045762=PMID:15563840, GO:0015031=PMID:14722252, GO:0007204=GO_REF:0000019, GO:0031623=PMID:10882736, GO:0030279=GO_REF:0000019, GO:0005887=PMID:7588285, GO:0008565=PMID:14722252, GO:0043025=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0007189=PMID:7619207} P30988 Calcitonin receptor protein 20090507 {GO:0005515=IPI, GO:0004948=IEA, GO:0030424=IEA, GO:0032841=IDA, GO:0043488=IEA, GO:0005886=TAS, GO:0001669=IEA, GO:0030819=IDA, GO:0030316=IEA, GO:0051384=IDA, GO:0045762=IDA, GO:0015031=IDA, GO:0007204=IEA, GO:0031623=IDA, GO:0030279=IEA, GO:0005887=NAS, GO:0008565=IDA, GO:0043025=IEA, GO:0016021=IEA, GO:0007189=IDA} adenylate cyclase-activating G-protein coupled receptor signaling pathway, elevation of cytosolic calcium ion concentration, negative regulation of ossification, osteoclast differentiation, positive regulation of adenylate cyclase activity, positive regulation of cAMP biosynthetic process, protein transport, receptor internalization, regulation of mRNA stability, response to glucocorticoid stimulus acrosomal vesicle, axon, integral to membrane, integral to plasma membrane, neuronal cell body, plasma membrane calcitonin binding, calcitonin receptor activity, protein binding, protein transporter activity Human CALCRL BHF-UCL UniProtKB {GO:0004948=GO_REF:0000019, GO:0005515=PMID:9620797, GO:0005886=PMID:18039931, GO:0004930=PMID:7818539, GO:0005783=PMID:10882736, GO:0001525=PMID:20596610, GO:0015031=PMID:9620797, GO:0048661=GO_REF:0000019, GO:0007507=GO_REF:0000019, GO:0031623=PMID:20074556, GO:0006937=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0007187=PMID:7818539, GO:0005887=PMID:7818539, GO:0001605=PMID:22102369, GO:0050728=GO_REF:0000019, GO:0071329=PMID:10882736, GO:0008565=PMID:9620797, GO:0006171=PMID:20074556, GO:0006816=PMID:10882736, GO:0007189=GO_REF:0000019, GO:0001635=GO_REF:0000019} Q16602 Calcitonin gene-related peptide type 1 receptor protein 20080908 {GO:0004948=IEA, GO:0005515=IPI, GO:0005886=IDA, GO:0004930=TAS, GO:0005783=IDA, GO:0001525=IDA, GO:0015031=IDA, GO:0048661=IEA, GO:0007507=IEA, GO:0031623=IDA, GO:0006937=IEA, GO:0016020=IEA, GO:0007187=TAS, GO:0005887=TAS, GO:0001605=IDA, GO:0050728=IEA, GO:0071329=IDA, GO:0008565=IDA, GO:0006171=IDA, GO:0006816=IDA, GO:0007189=IEA, GO:0001635=IEA} G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, adenylate cyclase-activating G-protein coupled receptor signaling pathway, angiogenesis, cAMP biosynthetic process, calcium ion transport, cellular response to sucrose stimulus, heart development, negative regulation of inflammatory response, positive regulation of smooth muscle cell proliferation, protein transport, receptor internalization, regulation of muscle contraction endoplasmic reticulum, integral to plasma membrane, membrane, plasma membrane G-protein coupled receptor activity, adrenomedullin receptor activity, calcitonin gene-related polypeptide receptor activity, calcitonin receptor activity, protein binding, protein transporter activity Human CALD1 HPA UniProtKB {GO:0005516=GO_REF:0000037, GO:0005886=GO_REF:0000052, GO:0030478=GO_REF:0000019, GO:0006928=PMID:16130169, GO:0003779=GO_REF:0000037, GO:0015629=GO_REF:0000052, GO:0030016=GO_REF:0000039, GO:0005829=Reactome:REACT_20663, GO:0006936=Reactome:REACT_20558, GO:0016020=GO_REF:0000019, GO:0017022=GO_REF:0000002, GO:0005856=PMID:16130169, GO:0005523=PMID:1555769} Q05682 Caldesmon protein 20110516 {GO:0005516=IEA, GO:0005886=IDA, GO:0030478=IEA, GO:0006928=TAS, GO:0003779=IEA, GO:0015629=IDA, GO:0030016=IEA, GO:0005829=TAS, GO:0006936=TAS, GO:0016020=IEA, GO:0017022=IEA, GO:0005856=TAS, GO:0005523=TAS} cellular component movement, muscle contraction actin cap, actin cytoskeleton, cytoskeleton, cytosol, membrane, myofibril, plasma membrane actin binding, calmodulin binding, myosin binding, tropomyosin binding Human CALM1 BHF-UCL UniProtKB {GO:0005515=PMID:21167176, GO:0005513=PMID:23040497, GO:0072542=PMID:8631777, GO:0006936=Reactome:REACT_20558, GO:0007173=Reactome:REACT_9417, GO:0043274=PMID:12821674, GO:0005813=PMID:16760425, GO:0032465=PMID:16760425, GO:0005975=Reactome:REACT_474, GO:0051343=PMID:8631777, GO:0005509=PMID:8631777, GO:0019904=PMID:11984006, GO:0030168=Reactome:REACT_798, GO:0031432=PMID:7607248, GO:0044325=PMID:23040497, GO:0051592=PMID:7607248, GO:0000922=PMID:16760425, GO:0007186=PMID:10899953, GO:0002027=PMID:23040497, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0055117=PMID:23040497, GO:0005654=Reactome:REACT_20666, GO:0030801=PMID:8631777, GO:0005980=Reactome:REACT_1008, GO:0016044=Reactome:REACT_11123, GO:0005886=Reactome:REACT_12620, GO:0043647=Reactome:REACT_150312, GO:0050999=Reactome:REACT_12477, GO:0007268=Reactome:REACT_13685, GO:0031996=PMID:16127172, GO:0007202=Reactome:REACT_12079, GO:0031997=PMID:15632291, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_150282, GO:0005737=PMID:10899953, GO:0060315=GO_REF:0000024, GO:0006006=Reactome:REACT_723, GO:0005876=PMID:16760425, GO:0046209=Reactome:REACT_12508, GO:0048011=Reactome:REACT_11061, GO:0035307=PMID:8631777, GO:1901844=GO_REF:0000036, GO:0010881=GO_REF:0000036, GO:0005576=Reactome:REACT_21347, GO:0034704=PMID:23040497, GO:0007165=Reactome:REACT_12478, GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0032516=PMID:8631777} P62158 Calmodulin protein 20130211 {GO:0005515=IPI, GO:0005513=IMP, GO:0072542=IDA, GO:0006936=TAS, GO:0007173=TAS, GO:0043274=IPI, GO:0005813=IDA, GO:0032465=IMP, GO:0005975=TAS, GO:0051343=IDA, GO:0005509=IDA, GO:0019904=IPI, GO:0030168=TAS, GO:0031432=IPI, GO:0044325=IPI, GO:0051592=IDA, GO:0000922=IDA, GO:0007186=TAS, GO:0002027=IMP, GO:0008543=TAS, GO:0045087=TAS, GO:0055117=IMP, GO:0005654=TAS, GO:0030801=IDA, GO:0005980=TAS, GO:0016044=TAS, GO:0005886=TAS, GO:0043647=TAS, GO:0050999=TAS, GO:0007268=TAS, GO:0031996=IPI, GO:0007202=TAS, GO:0031997=IPI, GO:0044281=TAS, GO:0005829=TAS, GO:0005737=TAS, GO:0060315=ISS, GO:0006006=TAS, GO:0005876=IDA, GO:0046209=TAS, GO:0048011=TAS, GO:0035307=IDA, GO:1901844=IC, GO:0010881=IC, GO:0005576=TAS, GO:0034704=IDA, GO:0007165=TAS, GO:0007596=TAS, GO:0002576=TAS, GO:0032516=IDA} G-protein coupled receptor signaling pathway, activation of phospholipase C activity, blood coagulation, carbohydrate metabolic process, cellular membrane organization, detection of calcium ion, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, glucose metabolic process, glycogen catabolic process, innate immune response, inositol phosphate metabolic process, muscle contraction, negative regulation of ryanodine-sensitive calcium-release channel activity, neurotrophin TRK receptor signaling pathway, nitric oxide metabolic process, platelet activation, platelet degranulation, positive regulation of cyclic nucleotide metabolic process, positive regulation of cyclic-nucleotide phosphodiesterase activity, positive regulation of phosphoprotein phosphatase activity, positive regulation of protein dephosphorylation, regulation of cardiac muscle contraction, regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion, regulation of cell communication by electrical coupling involved in cardiac conduction, regulation of cytokinesis, regulation of heart rate, regulation of nitric-oxide synthase activity, response to calcium ion, signal transduction, small molecule metabolic process, synaptic transmission calcium channel complex, centrosome, cytoplasm, cytosol, extracellular region, nucleoplasm, plasma membrane, spindle microtubule, spindle pole N-terminal myristoylation domain binding, calcium ion binding, ion channel binding, phospholipase binding, protein binding, protein domain specific binding, protein phosphatase activator activity, thioesterase binding, titin binding Human GO:0055117|GO:0060316 CALM2 InterPro UniProtKB {GO:0005509=GO_REF:0000002} H0Y7A7 Calmodulin protein 20130413 {GO:0005509=IEA} calcium ion binding Human InterPro:IPR001125|InterPro:IPR002048|InterPro:IPR011992 CALM3 UniProtKB UniProtKB {GO:0016301=GO_REF:0000038, GO:0005509=GO_REF:0000002} Q96HY3 Calmodulin 3 (Phosphorylase kinase, delta), isoform CRA_a protein 20130413 {GO:0016301=IEA, GO:0005509=IEA} calcium ion binding, kinase activity Human UniProtKB-KW:KW-0418 CALML3 InterPro UniProtKB {GO:0005509=GO_REF:0000002} P27482 Calmodulin-like protein 3 protein 20130413 {GO:0005509=IEA} calcium ion binding Human InterPro:IPR002048|InterPro:IPR011992 CALML5 PINC UniProtKB {GO:0007165=PMID:10777582, GO:0008544=PMID:10777582, GO:0005509=GO_REF:0000019} Q9NZT1 Calmodulin-like protein 5 protein 20030904 {GO:0007165=TAS, GO:0008544=TAS, GO:0005509=IEA} epidermis development, signal transduction calcium ion binding Human CALR BHF-UCL UniProtKB {GO:0017148=PMID:12242300, GO:0005515=PMID:17055437, GO:0002474=Reactome:REACT_75820, GO:0034504=PMID:15998798, GO:0050681=PMID:8107809, GO:0007283=GO_REF:0000019, GO:2000510=PMID:16140380, GO:0030968=Reactome:REACT_18356, GO:0005622=PMID:7841019, GO:1900026=PMID:11859136, GO:0006457=PMID:15474971, GO:0006611=PMID:11149926, GO:0055007=GO_REF:0000019, GO:0032355=GO_REF:0000019, GO:0031625=PMID:8666824, GO:0018279=Reactome:REACT_22426, GO:0071285=GO_REF:0000019, GO:0051208=PMID:15474971, GO:0005794=GO_REF:0000019, GO:0009986=PMID:15474971, GO:0005506=GO_REF:0000019, GO:0001849=PMID:15474971, GO:0045740=PMID:14726956, GO:0005509=GO_REF:0000024, GO:0000122=PMID:8107809, GO:0045787=PMID:14726956, GO:0005178=PMID:1911778, GO:0048387=PMID:8107809, GO:0042921=PMID:8107809, GO:0005788=Reactome:REACT_116001, GO:0008270=PMID:15474971, GO:0051082=PMID:15474971, GO:0006987=Reactome:REACT_18348, GO:0005844=PMID:14726956, GO:0044267=Reactome:REACT_17015, GO:0045892=PMID:8107809, GO:0009897=GO_REF:0000019, GO:0090398=PMID:14726956, GO:0043687=Reactome:REACT_22161, GO:0048471=PMID:1911778, GO:0042824=PMID:11825569, GO:0008284=PMID:14726956, GO:0005783=PMID:16130169, GO:0042562=GO_REF:0000019, GO:0051087=PMID:15474971, GO:0033144=PMID:8107809, GO:0005634=PMID:8107809, GO:0003729=PMID:14726956, GO:0005829=PMID:11149926, GO:0022417=PMID:17563366, GO:0005737=PMID:1911778, GO:0050766=GO_REF:0000024, GO:0071556=Reactome:REACT_75922, GO:0007050=PMID:14726956, GO:0002502=PMID:11825569, GO:0042277=GO_REF:0000019, GO:0006355=PMID:8107808, GO:0001669=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0005578=GO_REF:0000039, GO:0042590=Reactome:REACT_111119, GO:0050821=PMID:10581245, GO:0033018=GO_REF:0000039, GO:0006874=PMID:11149926, GO:0042981=PMID:16130169, GO:0033574=GO_REF:0000019, GO:0003677=PMID:11149926, GO:0040020=GO_REF:0000019, GO:0010628=GO_REF:0000019, GO:0045665=PMID:8107809, GO:0044183=PMID:15474971, GO:0030866=GO_REF:0000019, GO:0030246=PMID:15474971, GO:0002479=Reactome:REACT_111178} P27797 Calreticulin protein 20100524 {GO:0017148=TAS, GO:0005515=IPI, GO:0002474=TAS, GO:0034504=IDA, GO:0050681=IDA, GO:0007283=IEA, GO:2000510=IMP, GO:0030968=TAS, GO:0005622=TAS, GO:1900026=IMP, GO:0006457=TAS, GO:0006611=IDA, GO:0055007=IEA, GO:0032355=IEA, GO:0031625=IPI, GO:0018279=TAS, GO:0071285=IEA, GO:0051208=TAS, GO:0005794=IEA, GO:0009986=TAS, GO:0005506=IEA, GO:0001849=TAS, GO:0045740=IGI, GO:0005509=ISS, GO:0000122=IDA, GO:0045787=IGI, GO:0005178=IPI, GO:0048387=IDA, GO:0042921=TAS, GO:0005788=TAS, GO:0008270=TAS, GO:0051082=TAS, GO:0006987=TAS, GO:0005844=ISS, GO:0044267=TAS, GO:0045892=IDA, GO:0009897=IEA, GO:0090398=IGI, GO:0043687=TAS, GO:0048471=IDA, GO:0042824=ISS, GO:0008284=IGI, GO:0005783=TAS, GO:0042562=IEA, GO:0051087=TAS, GO:0033144=IDA, GO:0005634=IDA, GO:0003729=IDA, GO:0005829=IDA, GO:0022417=TAS, GO:0005737=IDA, GO:0050766=ISS, GO:0071556=TAS, GO:0007050=IGI, GO:0002502=ISS, GO:0042277=IEA, GO:0006355=TAS, GO:0001669=IEA, GO:0042493=IEA, GO:0005578=IEA, GO:0042590=TAS, GO:0050821=TAS, GO:0033018=IEA, GO:0006874=TAS, GO:0042981=TAS, GO:0033574=IEA, GO:0003677=NAS, GO:0040020=IEA, GO:0010628=IEA, GO:0045665=IDA, GO:0044183=TAS, GO:0030866=IEA, GO:0030246=TAS, GO:0002479=TAS} activation of signaling protein activity involved in unfolded protein response, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, cardiac muscle cell differentiation, cell cycle arrest, cellular calcium ion homeostasis, cellular protein metabolic process, cellular response to lithium ion, cellular senescence, cortical actin cytoskeleton organization, endoplasmic reticulum unfolded protein response, glucocorticoid receptor signaling pathway, negative regulation of intracellular steroid hormone receptor signaling pathway, negative regulation of neuron differentiation, negative regulation of retinoic acid receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, negative regulation of translation, peptide antigen assembly with MHC class I protein complex, positive regulation of DNA replication, positive regulation of cell cycle, positive regulation of cell proliferation, positive regulation of dendritic cell chemotaxis, positive regulation of gene expression, positive regulation of phagocytosis, positive regulation of substrate adhesion-dependent cell spreading, post-translational protein modification, protein N-linked glycosylation via asparagine, protein export from nucleus, protein folding, protein localization to nucleus, protein maturation by protein folding, protein stabilization, regulation of apoptotic process, regulation of meiosis, regulation of transcription, DNA-dependent, response to drug, response to estradiol stimulus, response to testosterone stimulus, sequestering of calcium ion, spermatogenesis Golgi apparatus, MHC class I peptide loading complex, acrosomal vesicle, cell surface, cytoplasm, cytosol, endoplasmic reticulum, endoplasmic reticulum lumen, external side of plasma membrane, integral to lumenal side of endoplasmic reticulum membrane, intracellular, nucleus, perinuclear region of cytoplasm, polysome, proteinaceous extracellular matrix, sarcoplasmic reticulum lumen DNA binding, androgen receptor binding, calcium ion binding, carbohydrate binding, chaperone binding, complement component C1q binding, hormone binding, integrin binding, iron ion binding, mRNA binding, peptide binding, protein binding, protein binding involved in protein folding, ubiquitin protein ligase binding, unfolded protein binding, zinc ion binding Human CALR3 UniProtKB UniProtKB {GO:0006457=GO_REF:0000002, GO:0005783=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0005788=GO_REF:0000039, GO:0007283=GO_REF:0000037, GO:0051082=GO_REF:0000002, GO:0030154=GO_REF:0000037} Q96L12 Calreticulin-3 protein 20130413 {GO:0006457=IEA, GO:0005783=IEA, GO:0005509=IEA, GO:0005788=IEA, GO:0007283=IEA, GO:0051082=IEA, GO:0030154=IEA} cell differentiation, protein folding, spermatogenesis endoplasmic reticulum, endoplasmic reticulum lumen calcium ion binding, unfolded protein binding Human UniProtKB-SubCell:SL-0096 CALU HPA UniProtKB {GO:0005515=PMID:18688696, GO:0008150=GO_REF:0000015, GO:0042470=GO_REF:0000039, GO:0005794=PMID:9218460, GO:0007596=Reactome:REACT_604, GO:0005783=GO_REF:0000052, GO:0002576=Reactome:REACT_318, GO:0005509=PMID:10094503, GO:0033018=GO_REF:0000039, GO:0030168=Reactome:REACT_798, GO:0005576=GO_REF:0000039} O43852 Calumenin protein 20080205 {GO:0005515=IPI, GO:0008150=ND, GO:0042470=IEA, GO:0005794=TAS, GO:0007596=TAS, GO:0005783=IDA, GO:0002576=TAS, GO:0005509=IDA, GO:0033018=IEA, GO:0030168=TAS, GO:0005576=IEA} biological_process, blood coagulation, platelet activation, platelet degranulation Golgi apparatus, endoplasmic reticulum, extracellular region, melanosome, sarcoplasmic reticulum lumen calcium ion binding, protein binding Human CALY UniProtKB UniProtKB {GO:0045807=PMID:16595675, GO:0032051=PMID:16595675, GO:0005887=PMID:14534309, GO:0031410=PMID:16595675, GO:0007212=GO_REF:0000002, GO:0030659=GO_REF:0000039, GO:0048268=PMID:16595675, GO:0006897=GO_REF:0000037} Q9NYX4 Neuron-specific vesicular protein calcyon protein 20080527 {GO:0045807=IMP, GO:0032051=IDA, GO:0005887=IDA, GO:0031410=IDA, GO:0007212=IEA, GO:0030659=IEA, GO:0048268=IDA, GO:0006897=IEA} clathrin coat assembly, dopamine receptor signaling pathway, endocytosis, positive regulation of endocytosis cytoplasmic vesicle, cytoplasmic vesicle membrane, integral to plasma membrane clathrin light chain binding Human CAMK1 BHF-UCL UniProtKB {GO:0005515=PMID:17442826, GO:0005516=GO_REF:0000037, GO:0071902=PMID:17442826, GO:0043393=PMID:11114197, GO:0005634=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0006913=GO_REF:0000019, GO:0046827=GO_REF:0000019, GO:0032880=PMID:11114197, GO:0007165=GO_REF:0000019, GO:0007049=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0051149=PMID:11081517, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000038, GO:0051835=PMID:18184567, GO:0010976=PMID:17442826, GO:0006468=PMID:11114197, GO:0004683=GO_REF:0000024, GO:0060999=PMID:18184567, GO:0051147=PMID:11114197} Q14012 Calcium/calmodulin-dependent protein kinase type 1 protein 20090805 {GO:0005515=IPI, GO:0005516=IEA, GO:0071902=IDA, GO:0043393=IDA, GO:0005634=IEA, GO:0005524=IEA, GO:0006913=IEA, GO:0046827=IEA, GO:0032880=IDA, GO:0007165=IEA, GO:0007049=IEA, GO:0005737=IEA, GO:0051149=IMP, GO:0004672=IEA, GO:0004674=IEA, GO:0051835=IMP, GO:0010976=IDA, GO:0006468=IDA, GO:0004683=ISS, GO:0060999=IMP, GO:0051147=IDA} cell cycle, nucleocytoplasmic transport, positive regulation of dendritic spine development, positive regulation of muscle cell differentiation, positive regulation of neuron projection development, positive regulation of protein export from nucleus, positive regulation of protein serine/threonine kinase activity, positive regulation of synapse structural plasticity, protein phosphorylation, regulation of muscle cell differentiation, regulation of protein binding, regulation of protein localization, signal transduction cytoplasm, nucleus ATP binding, calmodulin binding, calmodulin-dependent protein kinase activity, protein binding, protein kinase activity, protein serine/threonine kinase activity Human CAMK1D UniProtKB UniProtKB {GO:0005516=GO_REF:0000037, GO:0042981=GO_REF:0000019, GO:0071622=PMID:15840691, GO:0005634=PMID:16324104, GO:0005524=GO_REF:0000037, GO:0060267=PMID:15840691, GO:0032793=PMID:16324104, GO:0050766=PMID:15840691, GO:0005737=PMID:16324104, GO:0006954=GO_REF:0000037, GO:0010976=GO_REF:0000024, GO:0090023=GO_REF:0000024, GO:0050773=PMID:17056143, GO:0004683=GO_REF:0000003, GO:0005954=PMID:11264466} Q8IU85 Calcium/calmodulin-dependent protein kinase type 1D protein 20110913 {GO:0005516=IEA, GO:0042981=IEA, GO:0071622=IMP, GO:0005634=IDA, GO:0005524=IEA, GO:0060267=IMP, GO:0032793=IDA, GO:0050766=IMP, GO:0005737=IDA, GO:0006954=IEA, GO:0010976=ISS, GO:0090023=ISS, GO:0050773=IMP, GO:0004683=IEA, GO:0005954=TAS} inflammatory response, positive regulation of CREB transcription factor activity, positive regulation of neuron projection development, positive regulation of neutrophil chemotaxis, positive regulation of phagocytosis, positive regulation of respiratory burst, regulation of apoptotic process, regulation of dendrite development, regulation of granulocyte chemotaxis calcium- and calmodulin-dependent protein kinase complex, cytoplasm, nucleus ATP binding, calmodulin binding, calmodulin-dependent protein kinase activity Human UniProtKB:Q8BW96 CAMK1G UniProtKB UniProtKB {GO:0043005=GO_REF:0000019, GO:0005516=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0000139=GO_REF:0000039, GO:0004674=GO_REF:0000038, GO:0004683=GO_REF:0000003, GO:0005524=GO_REF:0000037, GO:0005954=GO_REF:0000019} Q96NX5 Calcium/calmodulin-dependent protein kinase type 1G protein 20130413 {GO:0043005=IEA, GO:0005516=IEA, GO:0005886=IEA, GO:0000139=IEA, GO:0004674=IEA, GO:0004683=IEA, GO:0005524=IEA, GO:0005954=IEA} Golgi membrane, calcium- and calmodulin-dependent protein kinase complex, neuron projection, plasma membrane ATP binding, calmodulin binding, calmodulin-dependent protein kinase activity, protein serine/threonine kinase activity Human UniProtKB-SubCell:SL-0039 CAMK2A Reactome UniProtKB {GO:0005515=PMID:17052756, GO:0005516=GO_REF:0000037, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_20670, GO:0019221=Reactome:REACT_25229, GO:0007268=Reactome:REACT_13685, GO:0046928=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_25369, GO:0030666=Reactome:REACT_18393, GO:0042734=GO_REF:0000039, GO:0000082=GO_REF:0000019, GO:0051092=PMID:17052756, GO:0046777=GO_REF:0000019, GO:0048168=GO_REF:0000019, GO:0016301=PMID:17052756, GO:0004674=GO_REF:0000019, GO:0035254=GO_REF:0000019, GO:0005654=Reactome:REACT_20634, GO:0006468=PMID:17052756, GO:0006816=GO_REF:0000019, GO:0004683=GO_REF:0000003, GO:0060333=Reactome:REACT_25078} Q9UQM7 Calcium/calmodulin-dependent protein kinase type II subunit alpha protein 20130228 {GO:0005515=IPI, GO:0005516=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0019221=TAS, GO:0007268=TAS, GO:0046928=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0030666=TAS, GO:0042734=IEA, GO:0000082=IEA, GO:0051092=IMP, GO:0046777=IEA, GO:0048168=IEA, GO:0016301=IDA, GO:0004674=IEA, GO:0035254=IEA, GO:0005654=TAS, GO:0006468=IDA, GO:0006816=IEA, GO:0004683=IEA, GO:0060333=TAS} G1/S transition of mitotic cell cycle, calcium ion transport, cytokine-mediated signaling pathway, interferon-gamma-mediated signaling pathway, positive regulation of NF-kappaB transcription factor activity, protein autophosphorylation, protein phosphorylation, regulation of neuronal synaptic plasticity, regulation of neurotransmitter secretion, synaptic transmission cell junction, cytosol, endocytic vesicle membrane, nucleoplasm, plasma membrane, presynaptic membrane ATP binding, calmodulin binding, calmodulin-dependent protein kinase activity, glutamate receptor binding, kinase activity, protein binding, protein serine/threonine kinase activity Human CAMK2B Reactome UniProtKB {GO:0005516=GO_REF:0000037, GO:0090129=GO_REF:0000024, GO:0005886=Reactome:REACT_20670, GO:0019221=Reactome:REACT_25229, GO:2001235=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0051233=GO_REF:0000019, GO:0005829=Reactome:REACT_25369, GO:0000082=GO_REF:0000019, GO:0051823=PMID:18817731, GO:0046777=PMID:18817731, GO:0018105=GO_REF:0000019, GO:0048169=PMID:18817731, GO:0050885=GO_REF:0000019, GO:0051924=PMID:15294044, GO:0006816=GO_REF:0000019, GO:0004683=GO_REF:0000003, GO:0060998=PMID:18817731, GO:0061003=GO_REF:0000024, GO:0060333=Reactome:REACT_25078, GO:0005815=GO_REF:0000039, GO:0033017=GO_REF:0000039, GO:0014733=PMID:15294044, GO:0003779=GO_REF:0000037, GO:0002030=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0030666=Reactome:REACT_18393, GO:0032222=GO_REF:0000019, GO:0007165=PMID:9060999, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000038, GO:0010976=GO_REF:0000024, GO:0005654=Reactome:REACT_20634, GO:0006468=PMID:9060999, GO:0060466=GO_REF:0000019, GO:0046686=GO_REF:0000019} Q13554 Calcium/calmodulin-dependent protein kinase type II subunit beta protein 20130228 {GO:0005516=IEA, GO:0090129=ISS, GO:0005886=TAS, GO:0019221=TAS, GO:2001235=IEA, GO:0007268=TAS, GO:0051233=IEA, GO:0005829=TAS, GO:0000082=IEA, GO:0051823=TAS, GO:0046777=IDA, GO:0018105=IEA, GO:0048169=TAS, GO:0050885=IEA, GO:0051924=TAS, GO:0006816=IEA, GO:0004683=IEA, GO:0060998=TAS, GO:0061003=ISS, GO:0060333=TAS, GO:0005815=IEA, GO:0033017=IEA, GO:0014733=TAS, GO:0003779=IEA, GO:0002030=IEA, GO:0005524=IEA, GO:0030666=TAS, GO:0032222=IEA, GO:0007165=TAS, GO:0004672=IEA, GO:0004674=IEA, GO:0010976=ISS, GO:0005654=TAS, GO:0006468=TAS, GO:0060466=IEA, GO:0046686=IEA} G1/S transition of mitotic cell cycle, activation of meiosis involved in egg activation, calcium ion transport, cytokine-mediated signaling pathway, inhibitory G-protein coupled receptor phosphorylation, interferon-gamma-mediated signaling pathway, neuromuscular process controlling balance, peptidyl-serine phosphorylation, positive regulation of apoptotic signaling pathway, positive regulation of dendritic spine morphogenesis, positive regulation of neuron projection development, positive regulation of synapse maturation, protein autophosphorylation, protein phosphorylation, regulation of calcium ion transport, regulation of dendritic spine development, regulation of long-term neuronal synaptic plasticity, regulation of skeletal muscle adaptation, regulation of synapse structural plasticity, regulation of synaptic transmission, cholinergic, response to cadmium ion, signal transduction, synaptic transmission cytosol, endocytic vesicle membrane, microtubule organizing center, nucleoplasm, plasma membrane, sarcoplasmic reticulum membrane, spindle midzone ATP binding, actin binding, calmodulin binding, calmodulin-dependent protein kinase activity, protein kinase activity, protein serine/threonine kinase activity Human CAMK2D Reactome UniProtKB {GO:0005516=GO_REF:0000037, GO:0031594=GO_REF:0000019, GO:0005886=Reactome:REACT_20670, GO:0019221=Reactome:REACT_25229, GO:0008016=PMID:17157285, GO:0007268=Reactome:REACT_13685, GO:0060048=GO_REF:0000019, GO:0001558=PMID:9060999, GO:0005829=Reactome:REACT_25369, GO:0043194=GO_REF:0000019, GO:0000082=GO_REF:0000019, GO:0046777=GO_REF:0000019, GO:0018105=GO_REF:0000019, GO:0014704=GO_REF:0000019, GO:0060314=PMID:19482609, GO:0043025=GO_REF:0000019, GO:0006816=GO_REF:0000019, GO:0004683=GO_REF:0000003, GO:0010613=PMID:17179159, GO:0060333=Reactome:REACT_25078, GO:0005954=PMID:11264466, GO:0030315=GO_REF:0000019, GO:0033017=GO_REF:0000039, GO:0010881=PMID:17157285, GO:0005524=GO_REF:0000029, GO:0030666=Reactome:REACT_18393, GO:0002028=GO_REF:0000019, GO:0006468=PMID:17179159, GO:0005654=Reactome:REACT_20634, GO:0060341=PMID:17179159} Q13557 Calcium/calmodulin-dependent protein kinase type II subunit delta protein 20130228 {GO:0005516=IEA, GO:0031594=IEA, GO:0005886=TAS, GO:0019221=TAS, GO:0008016=TAS, GO:0007268=TAS, GO:0060048=IEA, GO:0001558=NAS, GO:0005829=TAS, GO:0043194=IEA, GO:0000082=IEA, GO:0046777=IEA, GO:0018105=IEA, GO:0014704=IEA, GO:0060314=TAS, GO:0043025=IEA, GO:0006816=IEA, GO:0004683=IEA, GO:0010613=IMP, GO:0060333=TAS, GO:0005954=TAS, GO:0030315=IEA, GO:0033017=IEA, GO:0010881=TAS, GO:0005524=NAS, GO:0030666=TAS, GO:0002028=IEA, GO:0006468=IDA, GO:0005654=TAS, GO:0060341=IMP} G1/S transition of mitotic cell cycle, calcium ion transport, cardiac muscle contraction, cytokine-mediated signaling pathway, interferon-gamma-mediated signaling pathway, peptidyl-serine phosphorylation, positive regulation of cardiac muscle hypertrophy, protein autophosphorylation, protein phosphorylation, regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion, regulation of cell growth, regulation of cellular localization, regulation of heart contraction, regulation of ryanodine-sensitive calcium-release channel activity, regulation of sodium ion transport, synaptic transmission T-tubule, axon initial segment, calcium- and calmodulin-dependent protein kinase complex, cytosol, endocytic vesicle membrane, intercalated disc, neuromuscular junction, neuronal cell body, nucleoplasm, plasma membrane, sarcoplasmic reticulum membrane ATP binding, calmodulin binding, calmodulin-dependent protein kinase activity Human CAMK2G UniProtKB UniProtKB {GO:0005515=PMID:22939624, GO:0005516=GO_REF:0000002, GO:0005886=Reactome:REACT_20670, GO:0019221=Reactome:REACT_25229, GO:0007268=Reactome:REACT_13685, GO:0014733=PMID:15294044, GO:0033017=GO_REF:0000039, GO:0005524=GO_REF:0000038, GO:0030154=GO_REF:0000037, GO:0005829=Reactome:REACT_25369, GO:0007399=GO_REF:0000037, GO:0030666=Reactome:REACT_18393, GO:0000082=GO_REF:0000019, GO:0004672=GO_REF:0000002, GO:0046777=GO_REF:0000019, GO:0051924=PMID:15294044, GO:0004723=PMID:9060999, GO:0005654=Reactome:REACT_20634, GO:0006816=GO_REF:0000019, GO:0006468=GO_REF:0000029, GO:0004683=GO_REF:0000002, GO:0030073=PMID:9240463, GO:0060333=Reactome:REACT_25078, GO:0005954=PMID:11264466} Q8WU40 CAMK2G protein protein 20130413 {GO:0005515=IPI, GO:0005516=IEA, GO:0005886=TAS, GO:0019221=TAS, GO:0007268=TAS, GO:0014733=TAS, GO:0033017=IEA, GO:0005524=IEA, GO:0030154=IEA, GO:0005829=TAS, GO:0007399=IEA, GO:0030666=TAS, GO:0000082=IEA, GO:0004672=IEA, GO:0046777=IEA, GO:0051924=TAS, GO:0004723=NAS, GO:0005654=TAS, GO:0006816=IEA, GO:0006468=NAS, GO:0004683=IEA, GO:0030073=NAS, GO:0060333=TAS, GO:0005954=TAS} G1/S transition of mitotic cell cycle, calcium ion transport, cell differentiation, cytokine-mediated signaling pathway, insulin secretion, interferon-gamma-mediated signaling pathway, nervous system development, protein autophosphorylation, protein phosphorylation, regulation of calcium ion transport, regulation of skeletal muscle adaptation, synaptic transmission calcium- and calmodulin-dependent protein kinase complex, cytosol, endocytic vesicle membrane, nucleoplasm, plasma membrane, sarcoplasmic reticulum membrane ATP binding, calcium-dependent protein serine/threonine phosphatase activity, calmodulin binding, calmodulin-dependent protein kinase activity, protein binding, protein kinase activity Human UniProtKB-KW:KW-0067 CAMK2N1 UniProtKB UniProtKB {GO:0030054=GO_REF:0000037, GO:0019901=GO_REF:0000019, GO:0005886=GO_REF:0000037, GO:0045211=GO_REF:0000037, GO:0043025=GO_REF:0000019, GO:0008427=GO_REF:0000019, GO:0014069=GO_REF:0000039} Q7Z7J9 Calcium/calmodulin-dependent protein kinase II inhibitor 1 protein 20130413 {GO:0030054=IEA, GO:0019901=IEA, GO:0005886=IEA, GO:0045211=IEA, GO:0043025=IEA, GO:0008427=IEA, GO:0014069=IEA} cell junction, neuronal cell body, plasma membrane, postsynaptic density, postsynaptic membrane calcium-dependent protein kinase inhibitor activity, protein kinase binding Human UniProtKB-SubCell:SL-0297 CAMK2N2 UniProtKB UniProtKB {GO:0019901=GO_REF:0000019, GO:0008427=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0005829=GO_REF:0000039} Q96S95 Calcium/calmodulin-dependent protein kinase II inhibitor 2 protein 20130413 {GO:0019901=IEA, GO:0008427=IEA, GO:0005634=IEA, GO:0005829=IEA} cytosol, nucleus calcium-dependent protein kinase inhibitor activity, protein kinase binding Human UniProtKB-SubCell:SL-0091 CAMK4 HPA UniProtKB {GO:0005516=GO_REF:0000037, GO:0033081=PMID:18930438, GO:0007268=Reactome:REACT_13685, GO:0005634=GO_REF:0000052, GO:0007202=Reactome:REACT_12079, GO:0005829=Reactome:REACT_15332, GO:0046827=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0006954=GO_REF:0000037, GO:0007173=Reactome:REACT_9417, GO:0043011=PMID:17909078, GO:0004683=GO_REF:0000003, GO:0048011=Reactome:REACT_11061, GO:0007616=PMID:18829949, GO:0005730=GO_REF:0000052, GO:0045670=PMID:18930438, GO:0005524=GO_REF:0000037, GO:0007270=GO_REF:0000019, GO:0006913=GO_REF:0000019, GO:0007165=Reactome:REACT_12478, GO:0004672=GO_REF:0000002, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0006468=PMID:8089075, GO:0005654=Reactome:REACT_20666, GO:0002372=PMID:17909078, GO:0045893=PMID:8855261} Q16566 Calcium/calmodulin-dependent protein kinase type IV protein 20120912 {GO:0005516=IEA, GO:0033081=TAS, GO:0007268=TAS, GO:0005634=IDA, GO:0007202=TAS, GO:0005829=TAS, GO:0046827=IEA, GO:0005737=IEA, GO:0006954=IEA, GO:0007173=TAS, GO:0043011=IMP, GO:0004683=IEA, GO:0048011=TAS, GO:0007616=IGI, GO:0005730=IDA, GO:0045670=TAS, GO:0005524=IEA, GO:0007270=IEA, GO:0006913=IEA, GO:0007165=TAS, GO:0004672=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:0006468=TAS, GO:0005654=TAS, GO:0002372=IMP, GO:0045893=IDA} activation of phospholipase C activity, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, inflammatory response, innate immune response, long-term memory, myeloid dendritic cell cytokine production, myeloid dendritic cell differentiation, neuron-neuron synaptic transmission, neurotrophin TRK receptor signaling pathway, nucleocytoplasmic transport, positive regulation of protein export from nucleus, positive regulation of transcription, DNA-dependent, protein phosphorylation, regulation of T cell differentiation in thymus, regulation of osteoclast differentiation, signal transduction, synaptic transmission cytoplasm, cytosol, nucleolus, nucleoplasm, nucleus ATP binding, calmodulin binding, calmodulin-dependent protein kinase activity, protein kinase activity NOT Human CAMKK1 Reactome UniProtKB {GO:0005516=GO_REF:0000037, GO:0004674=GO_REF:0000038, GO:0007268=Reactome:REACT_13685, GO:0005634=GO_REF:0000039, GO:0004683=GO_REF:0000003, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_20635} Q8N5S9 Calcium/calmodulin-dependent protein kinase kinase 1 protein 20130301 {GO:0005516=IEA, GO:0004674=IEA, GO:0007268=TAS, GO:0005634=IEA, GO:0004683=IEA, GO:0005524=IEA, GO:0005829=TAS} synaptic transmission cytosol, nucleus ATP binding, calmodulin binding, calmodulin-dependent protein kinase activity, protein serine/threonine kinase activity Human CAMKK2 HPA UniProtKB {GO:0045859=PMID:11395482, GO:0005516=PMID:11395482, GO:0019722=PMID:11395482, GO:0005509=PMID:11395482, GO:0005634=GO_REF:0000039, GO:0042995=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0005622=PMID:11395482, GO:0005737=GO_REF:0000052, GO:0004672=GO_REF:0000002, GO:0046777=PMID:11395482, GO:0000165=PMID:11395482, GO:0004674=GO_REF:0000038, GO:0006468=PMID:11395482, GO:0004713=PMID:11395482, GO:0004683=GO_REF:0000003, GO:0045893=PMID:11395482} Q96RR4 Calcium/calmodulin-dependent protein kinase kinase 2 protein 20090616 {GO:0045859=TAS, GO:0005516=TAS, GO:0019722=TAS, GO:0005509=IDA, GO:0005634=IEA, GO:0042995=IEA, GO:0005524=IEA, GO:0005622=TAS, GO:0005737=IDA, GO:0004672=IEA, GO:0046777=IDA, GO:0000165=TAS, GO:0004674=IEA, GO:0006468=IDA, GO:0004713=TAS, GO:0004683=IEA, GO:0045893=TAS} MAPK cascade, calcium-mediated signaling, positive regulation of transcription, DNA-dependent, protein autophosphorylation, protein phosphorylation, regulation of protein kinase activity cell projection, cytoplasm, intracellular, nucleus ATP binding, calcium ion binding, calmodulin binding, calmodulin-dependent protein kinase activity, protein kinase activity, protein serine/threonine kinase activity, protein tyrosine kinase activity Human CAMKMT UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0018025=GO_REF:0000003} Q7Z624 Calmodulin-lysine N-methyltransferase protein 20130413 {GO:0005737=IEA, GO:0018025=IEA} cytoplasm calmodulin-lysine N-methyltransferase activity Human UniProtKB-SubCell:SL-0086 CAMKV UniProtKB UniProtKB {GO:0005516=GO_REF:0000037, GO:0004672=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0005524=GO_REF:0000002, GO:0030659=GO_REF:0000039} Q8NCB2 CaM kinase-like vesicle-associated protein protein 20130413 {GO:0005516=IEA, GO:0004672=IEA, GO:0005886=IEA, GO:0005524=IEA, GO:0030659=IEA} cytoplasmic vesicle membrane, plasma membrane ATP binding, calmodulin binding, protein kinase activity Human UniProtKB-SubCell:SL-0089 CAMLG IntAct UniProtKB {GO:0005515=PMID:15451437, GO:0007165=PMID:7522304, GO:0007173=GO_REF:0000019, GO:0001881=GO_REF:0000019, GO:0005783=PMID:12919676, GO:0006952=PMID:7522304, GO:0016021=GO_REF:0000037} P49069 Calcium signal-modulating cyclophilin ligand protein 20130415 {GO:0005515=IPI, GO:0007165=TAS, GO:0007173=IEA, GO:0001881=IEA, GO:0005783=IDA, GO:0006952=TAS, GO:0016021=IEA} defense response, epidermal growth factor receptor signaling pathway, receptor recycling, signal transduction endoplasmic reticulum, integral to membrane protein binding Human UniProtKB:P46695 CAMP Reactome UniProtKB {GO:0050829=GO_REF:0000019, GO:0051873=PMID:16177355, GO:0051701=Reactome:REACT_121237, GO:0050830=GO_REF:0000019, GO:0005618=Reactome:REACT_121346, GO:0042581=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0044130=GO_REF:0000019, GO:0090382=Reactome:REACT_121256, GO:0044140=PMID:16177355, GO:0042742=PMID:8681941, GO:0005829=Reactome:REACT_121346} P49913 Cathelicidin antimicrobial peptide protein 20130301 {GO:0050829=IEA, GO:0051873=IDA, GO:0051701=TAS, GO:0050830=IEA, GO:0005618=TAS, GO:0042581=IEA, GO:0005576=IEA, GO:0044130=IEA, GO:0090382=TAS, GO:0044140=IDA, GO:0042742=TAS, GO:0005829=TAS} defense response to Gram-negative bacterium, defense response to Gram-positive bacterium, defense response to bacterium, interaction with host, killing by host of symbiont cells, negative regulation of growth of symbiont in host, negative regulation of growth of symbiont on or near host surface, phagosome maturation cell wall, cytosol, extracellular region, specific granule Human CAMSAP1 UniProtKB UniProtKB {GO:0008017=GO_REF:0000002, GO:0005737=GO_REF:0000037, GO:0022604=PMID:21834987, GO:0007010=PMID:21834987, GO:0005874=GO_REF:0000037} Q5T5Y3 Calmodulin-regulated spectrin-associated protein 1 protein 20110926 {GO:0008017=IEA, GO:0005737=IEA, GO:0022604=IMP, GO:0007010=IMP, GO:0005874=IEA} cytoskeleton organization, regulation of cell morphogenesis cytoplasm, microtubule microtubule binding Human CAMSAP2 IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0008017=GO_REF:0000002, GO:0005737=GO_REF:0000037, GO:0005874=GO_REF:0000037} Q08AD1 Calmodulin-regulated spectrin-associated protein 2 protein 20130415 {GO:0005515=IPI, GO:0008017=IEA, GO:0005737=IEA, GO:0005874=IEA} cytoplasm, microtubule microtubule binding, protein binding Human UniProtKB:P29692 CAMSAP3 UniProtKB UniProtKB {GO:0070507=PMID:19041755, GO:0090136=PMID:19041755, GO:0005915=PMID:19041755, GO:0005737=PMID:19041755, GO:0034453=PMID:19041755, GO:0010923=PMID:19389623, GO:0051011=PMID:19041755, GO:0005874=GO_REF:0000037, GO:0045218=PMID:19041755} Q9P1Y5 Calmodulin-regulated spectrin-associated protein 3 protein 20111103 {GO:0070507=IMP, GO:0090136=IMP, GO:0005915=IDA, GO:0005737=IDA, GO:0034453=IMP, GO:0010923=IDA, GO:0051011=IDA, GO:0005874=IEA, GO:0045218=IMP} epithelial cell-cell adhesion, microtubule anchoring, negative regulation of phosphatase activity, regulation of microtubule cytoskeleton organization, zonula adherens maintenance cytoplasm, microtubule, zonula adherens microtubule minus-end binding Human CAMTA1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q9Y6Y1 Calmodulin-binding transcription activator 1 protein 20110516 {GO:0005737=IDA, GO:0006355=IEA, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus DNA binding Human CAMTA2 IntAct UniProtKB {GO:0005515=PMID:16678093, GO:0042826=PMID:16678093, GO:0006357=PMID:16678093, GO:0045944=PMID:16678093, GO:0003682=PMID:16678093, GO:0014898=PMID:16678093, GO:0005634=PMID:16678093, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0008134=PMID:16678093} O94983 Calmodulin-binding transcription activator 2 protein 20130415 {GO:0005515=IPI, GO:0042826=IDA, GO:0006357=IDA, GO:0045944=IGI, GO:0003682=IDA, GO:0014898=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA, GO:0008134=IGI} cardiac muscle hypertrophy in response to stress, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding, chromatin binding, histone deacetylase binding, protein binding, transcription factor binding Human UniProtKB:P42582 CAND1 MGI UniProtKB {GO:0005515=PMID:18826954, GO:0031461=PMID:22405651, GO:0005737=PMID:21249194, GO:0016567=PMID:21249194, GO:0045899=GO_REF:0000019, GO:0000151=PMID:12609982, GO:0017025=GO_REF:0000019, GO:0005634=PMID:21249194, GO:0010265=PMID:21249194, GO:0043086=PMID:12609982, GO:0030154=PMID:10581176} Q86VP6 Cullin-associated NEDD8-dissociated protein 1 protein 20121116 {GO:0005515=IPI, GO:0031461=IDA, GO:0005737=IDA, GO:0016567=IDA, GO:0045899=IEA, GO:0000151=IDA, GO:0017025=IEA, GO:0005634=IDA, GO:0010265=IDA, GO:0043086=IDA, GO:0030154=IDA} SCF complex assembly, cell differentiation, negative regulation of catalytic activity, positive regulation of RNA polymerase II transcriptional preinitiation complex assembly, protein ubiquitination cullin-RING ubiquitin ligase complex, cytoplasm, nucleus, ubiquitin ligase complex TBP-class protein binding, protein binding Human CAND2 UniProtKB UniProtKB {GO:0005515=PMID:12692129, GO:0005622=PMID:12692129, GO:0017025=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0045893=GO_REF:0000024, GO:0006351=GO_REF:0000037} O75155 Cullin-associated NEDD8-dissociated protein 2 protein 20040420 {GO:0005515=IPI, GO:0005622=IDA, GO:0017025=IEA, GO:0005634=IEA, GO:0045893=ISS, GO:0006351=IEA} positive regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus TBP-class protein binding, protein binding Human UniProtKB:Q15386 CANT1 GOC UniProtKB {GO:0007165=PMID:12761501, GO:0016462=GO_REF:0000002, GO:0032580=GO_REF:0000039, GO:0045134=GO_REF:0000003, GO:0005509=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0004871=PMID:12761501, GO:0016021=GO_REF:0000037, GO:0043123=PMID:12761501, GO:0030166=PMID:22539336} Q8WVQ1 Soluble calcium-activated nucleotidase 1 protein 20130413 {GO:0007165=IMP, GO:0016462=IEA, GO:0032580=IEA, GO:0045134=IEA, GO:0005509=IEA, GO:0005789=IEA, GO:0004871=IMP, GO:0016021=IEA, GO:0043123=IMP, GO:0030166=IMP} positive regulation of I-kappaB kinase/NF-kappaB cascade, proteoglycan biosynthetic process, signal transduction Golgi cisterna membrane, endoplasmic reticulum membrane, integral to membrane calcium ion binding, pyrophosphatase activity, signal transducer activity, uridine-diphosphatase activity Human CANX HPA UniProtKB {GO:0072583=GO_REF:0000024, GO:0005515=PMID:17220478, GO:0030424=GO_REF:0000019, GO:0002474=Reactome:REACT_75820, GO:0009306=PMID:8055875, GO:0005783=GO_REF:0000052, GO:0032839=GO_REF:0000019, GO:0019886=Reactome:REACT_121399, GO:0043197=GO_REF:0000019, GO:0006457=Reactome:REACT_23878, GO:0043025=GO_REF:0000019, GO:0071556=Reactome:REACT_75898, GO:0018279=Reactome:REACT_22426, GO:0042470=GO_REF:0000039, GO:0007568=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0048488=GO_REF:0000024, GO:0035255=GO_REF:0000019, GO:0005789=PMID:19723497, GO:0005840=GO_REF:0000019, GO:0005788=Reactome:REACT_121334, GO:0051082=GO_REF:0000029, GO:0034185=GO_REF:0000019, GO:0016021=GO_REF:0000019, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} P27824 Calnexin protein 20080205 {GO:0072583=ISS, GO:0005515=IPI, GO:0030424=IEA, GO:0002474=TAS, GO:0009306=TAS, GO:0005783=IDA, GO:0032839=IEA, GO:0019886=TAS, GO:0043197=IEA, GO:0006457=TAS, GO:0043025=IEA, GO:0071556=TAS, GO:0018279=TAS, GO:0042470=IEA, GO:0007568=IEA, GO:0005509=IEA, GO:0048488=ISS, GO:0035255=IEA, GO:0005789=IDA, GO:0005840=IEA, GO:0005788=TAS, GO:0051082=NAS, GO:0034185=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0043687=TAS} aging, antigen processing and presentation of exogenous peptide antigen via MHC class II, antigen processing and presentation of peptide antigen via MHC class I, cellular protein metabolic process, clathrin-mediated endocytosis, post-translational protein modification, protein N-linked glycosylation via asparagine, protein folding, protein secretion, synaptic vesicle endocytosis axon, dendrite cytoplasm, dendritic spine, endoplasmic reticulum, endoplasmic reticulum lumen, endoplasmic reticulum membrane, integral to lumenal side of endoplasmic reticulum membrane, integral to membrane, melanosome, neuronal cell body, ribosome apolipoprotein binding, calcium ion binding, ionotropic glutamate receptor binding, protein binding, unfolded protein binding Human CAP1 InterPro UniProtKB {GO:0030036=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0001667=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0003779=GO_REF:0000002, GO:0006898=GO_REF:0000019, GO:0000902=GO_REF:0000019, GO:0007190=PMID:7962207, GO:0007165=PMID:1406678, GO:0007163=PMID:1406678, GO:0007411=Reactome:REACT_18266, GO:0007596=Reactome:REACT_604, GO:0007010=GO_REF:0000002, GO:0002576=Reactome:REACT_318, GO:0030864=GO_REF:0000019} Q5T0S3 Adenylyl cyclase-associated protein 1 protein 20130413 {GO:0030036=IEA, GO:0005886=IEA, GO:0001667=IEA, GO:0030168=TAS, GO:0003779=IEA, GO:0006898=IEA, GO:0000902=IEA, GO:0007190=TAS, GO:0007165=TAS, GO:0007163=TAS, GO:0007411=TAS, GO:0007596=TAS, GO:0007010=IEA, GO:0002576=TAS, GO:0030864=IEA} actin cytoskeleton organization, activation of adenylate cyclase activity, ameboidal cell migration, axon guidance, blood coagulation, cell morphogenesis, cytoskeleton organization, establishment or maintenance of cell polarity, platelet activation, platelet degranulation, receptor-mediated endocytosis, signal transduction cortical actin cytoskeleton, plasma membrane actin binding Human InterPro:IPR001837|InterPro:IPR013992|InterPro:IPR018106 CAP2 Reactome UniProtKB {GO:0007190=PMID:7962207, GO:0007165=PMID:7962207, GO:0000902=GO_REF:0000002, GO:0007163=PMID:7962207, GO:0005886=GO_REF:0000039, GO:0007411=Reactome:REACT_18266, GO:0007010=GO_REF:0000002, GO:0003779=GO_REF:0000002} P40123 Adenylyl cyclase-associated protein 2 protein 20130301 {GO:0007190=TAS, GO:0007165=TAS, GO:0000902=IEA, GO:0007163=TAS, GO:0005886=IEA, GO:0007411=TAS, GO:0007010=IEA, GO:0003779=IEA} activation of adenylate cyclase activity, axon guidance, cell morphogenesis, cytoskeleton organization, establishment or maintenance of cell polarity, signal transduction plasma membrane actin binding Human CAPG HPA UniProtKB {GO:0042470=GO_REF:0000039, GO:0051016=PMID:1322908, GO:0031965=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0006461=PMID:1322908, GO:0030031=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0008290=PMID:1322908, GO:0005634=GO_REF:0000052, GO:0003779=GO_REF:0000037} P40121 Macrophage-capping protein protein 20101115 {GO:0042470=IEA, GO:0051016=TAS, GO:0031965=IDA, GO:0005737=IDA, GO:0006461=NAS, GO:0030031=IEA, GO:0005730=IDA, GO:0008290=TAS, GO:0005634=IDA, GO:0003779=IEA} barbed-end actin filament capping, cell projection assembly, protein complex assembly F-actin capping protein complex, cytoplasm, melanosome, nuclear membrane, nucleolus, nucleus actin binding Human CAPN1 HPA UniProtKB {GO:0005515=PMID:21988832, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0008284=PMID:8702541, GO:0004198=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0032801=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0006508=GO_REF:0000037} P07384 Calpain-1 catalytic subunit protein 20080205 {GO:0005515=IPI, GO:0005622=IEA, GO:0005737=IDA, GO:0008284=TAS, GO:0004198=IEA, GO:0005886=IEA, GO:0032801=IEA, GO:0005509=IEA, GO:0006508=IEA} positive regulation of cell proliferation, proteolysis, receptor catabolic process cytoplasm, intracellular, plasma membrane calcium ion binding, calcium-dependent cysteine-type endopeptidase activity, protein binding Human CAPN10 BHF-UCL UniProtKB {GO:0032388=PMID:12974673, GO:0008092=GO_REF:0000024, GO:0032869=PMID:17572128, GO:0043065=PMID:15044459, GO:0031532=PMID:12974673, GO:0005886=GO_REF:0000024, GO:0005623=PMID:17572128, GO:0005829=GO_REF:0000024, GO:0005622=GO_REF:0000002, GO:0004198=PMID:15044459, GO:0046326=PMID:17572128, GO:0000149=GO_REF:0000024, GO:0006508=PMID:15044459, GO:0032024=PMID:15471947} Q9HC96 Calpain-10 protein 20080214 {GO:0032388=ISS, GO:0008092=ISS, GO:0032869=IMP, GO:0043065=IMP, GO:0031532=ISS, GO:0005886=ISS, GO:0005623=IDA, GO:0005829=ISS, GO:0005622=IEA, GO:0004198=IMP, GO:0046326=IMP, GO:0000149=ISS, GO:0006508=IMP, GO:0032024=IMP} actin cytoskeleton reorganization, cellular response to insulin stimulus, positive regulation of apoptotic process, positive regulation of glucose import, positive regulation of insulin secretion, positive regulation of intracellular transport, proteolysis cell, cytosol, intracellular, plasma membrane SNARE binding, calcium-dependent cysteine-type endopeptidase activity, cytoskeletal protein binding Human CAPN11 PINC UniProtKB {GO:0005622=GO_REF:0000002, GO:0004198=GO_REF:0000002, GO:0001669=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0008233=PMID:10409436} Q9UMQ6 Calpain-11 protein 20030904 {GO:0005622=IEA, GO:0004198=IEA, GO:0001669=IEA, GO:0005509=IEA, GO:0006508=IEA, GO:0008233=TAS} proteolysis acrosomal vesicle, intracellular calcium ion binding, calcium-dependent cysteine-type endopeptidase activity, peptidase activity Human CAPN2 IntAct UniProtKB {GO:0005515=PMID:10639123, GO:0008092=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0016540=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0046982=GO_REF:0000019, GO:0001824=GO_REF:0000019, GO:0005509=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0007520=GO_REF:0000019, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0004198=GO_REF:0000019, GO:0006508=GO_REF:0000037, GO:0008234=PMID:2209092, GO:0000785=GO_REF:0000019} P17655 Calpain-2 catalytic subunit protein 20130415 {GO:0005515=IPI, GO:0008092=IEA, GO:0001666=IEA, GO:0016540=IEA, GO:0005886=IEA, GO:0046982=IEA, GO:0001824=IEA, GO:0005509=IEA, GO:0005634=IEA, GO:0007520=IEA, GO:0005622=IEA, GO:0005737=IEA, GO:0004198=IEA, GO:0006508=IEA, GO:0008234=TAS, GO:0000785=IEA} blastocyst development, myoblast fusion, protein autoprocessing, proteolysis, response to hypoxia chromatin, cytoplasm, intracellular, nucleus, plasma membrane calcium ion binding, calcium-dependent cysteine-type endopeptidase activity, cysteine-type peptidase activity, cytoskeletal protein binding, protein binding, protein heterodimerization activity Human UniProtKB:P04632 CAPN3 GOC UniProtKB {GO:0030018=GO_REF:0000024, GO:0005886=GO_REF:0000024, GO:0005634=PMID:19386580, GO:0030016=GO_REF:0000024, GO:0003824=PMID:9642272, GO:0031402=GO_REF:0000024, GO:0046716=PMID:19386580, GO:0005829=GO_REF:0000024, GO:0045661=GO_REF:0000019, GO:0005622=PMID:9642272, GO:0005737=PMID:19386580, GO:0051092=PMID:18073330, GO:0001896=GO_REF:0000019, GO:0030239=GO_REF:0000024, GO:0006508=PMID:19386580, GO:0071277=GO_REF:0000024, GO:0004871=PMID:7720071, GO:0033234=PMID:20694146, GO:0008307=GO_REF:0000024, GO:0043122=PMID:18073330, GO:0051281=GO_REF:0000024, GO:0043066=PMID:18073330, GO:0014850=GO_REF:0000024, GO:0014718=GO_REF:0000024, GO:0005509=GO_REF:0000024, GO:0071472=GO_REF:0000024, GO:0045214=GO_REF:0000024, GO:0030315=GO_REF:0000024, GO:0006915=PMID:19386580, GO:0070315=GO_REF:0000019, GO:0072657=GO_REF:0000024, GO:0061061=GO_REF:0000024, GO:0045862=GO_REF:0000024, GO:0031432=PMID:18310072, GO:0007165=PMID:7720071, GO:0051592=GO_REF:0000024, GO:0043234=GO_REF:0000024, GO:0050790=PMID:20694146, GO:0032947=GO_REF:0000024, GO:0007517=PMID:9642272, GO:0006461=GO_REF:0000024, GO:0004198=GO_REF:0000024, GO:0008233=PMID:9642272, GO:0008234=PMID:2555341, GO:0045893=GO_REF:0000019, GO:0045892=GO_REF:0000024} P20807 Calpain-3 protein 20130413 {GO:0030018=ISS, GO:0005886=ISS, GO:0005634=IDA, GO:0030016=ISS, GO:0003824=IDA, GO:0031402=ISS, GO:0046716=TAS, GO:0005829=ISS, GO:0045661=IEA, GO:0005622=TAS, GO:0005737=IDA, GO:0051092=IMP, GO:0001896=IEA, GO:0030239=ISS, GO:0006508=IDA, GO:0071277=ISS, GO:0004871=TAS, GO:0033234=IDA, GO:0008307=ISS, GO:0043122=IMP, GO:0051281=ISS, GO:0043066=IMP, GO:0014850=ISS, GO:0014718=ISS, GO:0005509=ISS, GO:0071472=ISS, GO:0045214=ISS, GO:0030315=ISS, GO:0006915=TAS, GO:0070315=IEA, GO:0072657=ISS, GO:0061061=ISS, GO:0045862=ISS, GO:0031432=IPI, GO:0007165=TAS, GO:0051592=ISS, GO:0043234=ISS, GO:0050790=IDA, GO:0032947=ISS, GO:0007517=TAS, GO:0006461=ISS, GO:0004198=ISS, GO:0008233=IDA, GO:0008234=TAS, GO:0045893=IEA, GO:0045892=ISS} G1 to G0 transition involved in cell differentiation, apoptotic process, autolysis, cellular response to calcium ion, cellular response to salt stress, muscle cell homeostasis, muscle organ development, muscle structure development, myofibril assembly, negative regulation of apoptotic process, negative regulation of protein sumoylation, negative regulation of transcription, DNA-dependent, positive regulation of NF-kappaB transcription factor activity, positive regulation of proteolysis, positive regulation of release of sequestered calcium ion into cytosol, positive regulation of satellite cell activation involved in skeletal muscle regeneration, positive regulation of transcription, DNA-dependent, protein complex assembly, protein localization to membrane, proteolysis, regulation of I-kappaB kinase/NF-kappaB cascade, regulation of catalytic activity, regulation of myoblast differentiation, response to calcium ion, response to muscle activity, sarcomere organization, signal transduction T-tubule, Z disc, cytoplasm, cytosol, intracellular, myofibril, nucleus, plasma membrane, protein complex calcium ion binding, calcium-dependent cysteine-type endopeptidase activity, catalytic activity, cysteine-type peptidase activity, peptidase activity, protein complex scaffold, signal transducer activity, sodium ion binding, structural constituent of muscle, titin binding Human CAPN5 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0007165=PMID:9339374, GO:0004198=GO_REF:0000002, GO:0009986=PMID:23055945, GO:0006508=GO_REF:0000037} O15484 Calpain-5 protein 20130318 {GO:0005622=IEA, GO:0007165=TAS, GO:0004198=IEA, GO:0009986=IDA, GO:0006508=IEA} proteolysis, signal transduction cell surface, intracellular calcium-dependent cysteine-type endopeptidase activity Human CAPN6 UniProtKB UniProtKB {GO:0008017=GO_REF:0000024, GO:0048471=PMID:17210638, GO:0004198=GO_REF:0000002, GO:0051493=GO_REF:0000024, GO:0001578=GO_REF:0000024, GO:0005874=GO_REF:0000019, GO:0006508=GO_REF:0000002, GO:0005876=PMID:17210638} Q9Y6Q1 Calpain-6 protein 20110321 {GO:0008017=ISS, GO:0048471=IDA, GO:0004198=IEA, GO:0051493=ISS, GO:0001578=ISS, GO:0005874=IEA, GO:0006508=IEA, GO:0005876=IDA} microtubule bundle formation, proteolysis, regulation of cytoskeleton organization microtubule, perinuclear region of cytoplasm, spindle microtubule calcium-dependent cysteine-type endopeptidase activity, microtubule binding Human UniProtKB:O35646 CAPN7 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0090541=PMID:20849418, GO:0004198=GO_REF:0000002, GO:0097264=PMID:20849418, GO:0006508=GO_REF:0000002, GO:0005634=GO_REF:0000039} Q9Y6W3 Calpain-7 protein 20130215 {GO:0005622=IEA, GO:0090541=IPI, GO:0004198=IEA, GO:0097264=IDA, GO:0006508=IEA, GO:0005634=IEA} proteolysis, self proteolysis intracellular, nucleus MIT domain binding, calcium-dependent cysteine-type endopeptidase activity Human CAPNS1 IntAct UniProtKB {GO:0005515=PMID:10639123, GO:0008284=PMID:8702541, GO:0005737=GO_REF:0000039, GO:0004198=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002} P04632 Calpain small subunit 1 protein 20130415 {GO:0005515=IPI, GO:0008284=TAS, GO:0005737=IEA, GO:0004198=IEA, GO:0005886=IEA, GO:0005509=IEA} positive regulation of cell proliferation cytoplasm, plasma membrane calcium ion binding, calcium-dependent cysteine-type endopeptidase activity, protein binding Human UniProtKB:P17655 CAPNS2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002} Q96L46 Calpain small subunit 2 protein 20130413 {GO:0005737=IEA, GO:0005886=IEA, GO:0005509=IEA} cytoplasm, plasma membrane calcium ion binding Human UniProtKB-SubCell:SL-0039 CAPRIN1 HPA UniProtKB {GO:0017148=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0005887=PMID:7657653, GO:0010494=GO_REF:0000024, GO:0000932=GO_REF:0000024, GO:0050775=GO_REF:0000024, GO:0003723=GO_REF:0000024, GO:0030425=GO_REF:0000039, GO:0061003=GO_REF:0000024, GO:0005829=GO_REF:0000039} Q14444 Caprin-1 protein 20100326 {GO:0017148=ISS, GO:0005737=IDA, GO:0005887=TAS, GO:0010494=ISS, GO:0000932=ISS, GO:0050775=ISS, GO:0003723=ISS, GO:0030425=IEA, GO:0061003=ISS, GO:0005829=IEA} negative regulation of translation, positive regulation of dendrite morphogenesis, positive regulation of dendritic spine morphogenesis cytoplasm, cytoplasmic mRNA processing body, cytoplasmic stress granule, cytosol, dendrite, integral to plasma membrane RNA binding Human CAPRIN2 BHF-UCL UniProtKB {GO:0017148=GO_REF:0000037, GO:0030308=PMID:14593112, GO:0003723=GO_REF:0000037, GO:0090263=PMID:18762581, GO:0005102=PMID:18762581, GO:0032092=PMID:18762581, GO:0005739=PMID:14593112, GO:0043235=PMID:18762581, GO:0005737=PMID:14593112, GO:0033138=PMID:18762581, GO:0050775=GO_REF:0000024, GO:0045944=PMID:18762581, GO:0061003=GO_REF:0000024} Q6IMN6 Caprin-2 protein 20110203 {GO:0017148=IEA, GO:0030308=IDA, GO:0003723=IEA, GO:0090263=IDA, GO:0005102=IPI, GO:0032092=IDA, GO:0005739=IDA, GO:0043235=IDA, GO:0005737=IDA, GO:0033138=IDA, GO:0050775=ISS, GO:0045944=IDA, GO:0061003=ISS} negative regulation of cell growth, negative regulation of translation, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of dendrite morphogenesis, positive regulation of dendritic spine morphogenesis, positive regulation of peptidyl-serine phosphorylation, positive regulation of protein binding, positive regulation of transcription from RNA polymerase II promoter cytoplasm, mitochondrion, receptor complex RNA binding, receptor binding Human CAPSL UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005509=GO_REF:0000002} Q8WWF8 Calcyphosin-like protein protein 20130413 {GO:0005737=IEA, GO:0005509=IEA} cytoplasm calcium ion binding Human UniProtKB-SubCell:SL-0086 CAPZA1 Reactome UniProtKB {GO:0030036=GO_REF:0000002, GO:0006928=PMID:16130169, GO:0003779=GO_REF:0000037, GO:0005576=Reactome:REACT_25219, GO:0015629=PMID:7665558, GO:0051693=GO_REF:0000037, GO:0005829=Reactome:REACT_25363, GO:0006461=PMID:9331217, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0071203=PMID:19922875, GO:0008290=GO_REF:0000002, GO:0005856=PMID:16130169} P52907 F-actin-capping protein subunit alpha-1 protein 20130301 {GO:0030036=IEA, GO:0006928=TAS, GO:0003779=IEA, GO:0005576=TAS, GO:0015629=TAS, GO:0051693=IEA, GO:0005829=TAS, GO:0006461=TAS, GO:0007596=TAS, GO:0045087=TAS, GO:0071203=IDA, GO:0008290=IEA, GO:0005856=TAS} actin cytoskeleton organization, actin filament capping, blood coagulation, cellular component movement, innate immune response, protein complex assembly F-actin capping protein complex, WASH complex, actin cytoskeleton, cytoskeleton, cytosol, extracellular region actin binding Human CAPZA2 HPA UniProtKB {GO:0030036=GO_REF:0000002, GO:0006928=PMID:9331217, GO:0003779=GO_REF:0000037, GO:0005576=Reactome:REACT_25219, GO:0015629=PMID:9331217, GO:0051693=GO_REF:0000037, GO:0005829=Reactome:REACT_25363, GO:0005737=GO_REF:0000052, GO:0006461=PMID:9331217, GO:0016020=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0008290=GO_REF:0000002, GO:0030863=GO_REF:0000019} P47755 F-actin-capping protein subunit alpha-2 protein 20080818 {GO:0030036=IEA, GO:0006928=TAS, GO:0003779=IEA, GO:0005576=TAS, GO:0015629=TAS, GO:0051693=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0006461=TAS, GO:0016020=IEA, GO:0007596=TAS, GO:0045087=TAS, GO:0008290=IEA, GO:0030863=IEA} actin cytoskeleton organization, actin filament capping, blood coagulation, cellular component movement, innate immune response, protein complex assembly F-actin capping protein complex, actin cytoskeleton, cortical cytoskeleton, cytoplasm, cytosol, extracellular region, membrane actin binding Human CAPZA3 ENSEMBL UniProtKB {GO:0030036=GO_REF:0000002, GO:0016020=GO_REF:0000019, GO:0030863=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0008290=GO_REF:0000002, GO:0051693=GO_REF:0000037} Q96KX2 F-actin-capping protein subunit alpha-3 protein 20130413 {GO:0030036=IEA, GO:0016020=IEA, GO:0030863=IEA, GO:0003779=IEA, GO:0008290=IEA, GO:0051693=IEA} actin cytoskeleton organization, actin filament capping F-actin capping protein complex, cortical cytoskeleton, membrane actin binding Human Ensembl:ENSMUSP00000038562 CAPZB Reactome UniProtKB {GO:0030036=GO_REF:0000002, GO:0030032=GO_REF:0000019, GO:0006928=PMID:16130169, GO:0003779=GO_REF:0000037, GO:0015629=PMID:7665558, GO:0030027=GO_REF:0000019, GO:0005829=Reactome:REACT_25363, GO:0051693=GO_REF:0000037, GO:0016020=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0007010=PMID:21834987, GO:0022604=PMID:21834987, GO:0071203=PMID:19922875, GO:0008290=GO_REF:0000002, GO:0030863=GO_REF:0000019, GO:0005856=PMID:16130169} P47756 F-actin-capping protein subunit beta protein 20100617 {GO:0030036=IEA, GO:0030032=IEA, GO:0006928=TAS, GO:0003779=IEA, GO:0015629=TAS, GO:0030027=IEA, GO:0005829=TAS, GO:0051693=IEA, GO:0016020=IEA, GO:0007596=TAS, GO:0007010=IMP, GO:0022604=IMP, GO:0071203=IDA, GO:0008290=IEA, GO:0030863=IEA, GO:0005856=TAS} actin cytoskeleton organization, actin filament capping, blood coagulation, cellular component movement, cytoskeleton organization, lamellipodium assembly, regulation of cell morphogenesis F-actin capping protein complex, WASH complex, actin cytoskeleton, cortical cytoskeleton, cytoskeleton, cytosol, lamellipodium, membrane actin binding Human CARD10 UniProtKB UniProtKB {GO:0005515=PMID:11259443, GO:0005737=PMID:11259443, GO:0006461=PMID:11259443, GO:0032449=PMID:15125833, GO:0007250=PMID:11259443, GO:0030159=PMID:11259443, GO:0042981=GO_REF:0000002} Q9BWT7 Caspase recruitment domain-containing protein 10 protein 20061124 {GO:0005515=IPI, GO:0005737=NAS, GO:0006461=NAS, GO:0032449=NAS, GO:0007250=IDA, GO:0030159=NAS, GO:0042981=IEA} activation of NF-kappaB-inducing kinase activity, protein complex assembly, regulation of apoptotic process CBM complex, cytoplasm protein binding, receptor signaling complex scaffold activity Human CARD11 Reactome UniProtKB {GO:0005515=PMID:17287217, GO:0050700=PMID:11278692, GO:0050852=Reactome:REACT_12526, GO:0045577=GO_REF:0000019, GO:0005886=Reactome:REACT_118777, GO:0030890=GO_REF:0000019, GO:0031295=PMID:17287217, GO:0004385=PMID:11278692, GO:0042981=GO_REF:0000002, GO:0001819=PMID:12154360, GO:0005829=Reactome:REACT_118598, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000019, GO:0045086=GO_REF:0000019, GO:0005737=PMID:12154360, GO:0051092=PMID:12154360, GO:0042101=PMID:12154360, GO:0045061=GO_REF:0000019, GO:0042102=GO_REF:0000019, GO:0050776=GO_REF:0000019, GO:0045580=GO_REF:0000019, GO:0045121=PMID:17287217, GO:0043123=GO_REF:0000019} Q9BXL7 Caspase recruitment domain-containing protein 11 protein 20071029 {GO:0005515=IPI, GO:0050700=IPI, GO:0050852=TAS, GO:0045577=IEA, GO:0005886=TAS, GO:0030890=IEA, GO:0031295=IDA, GO:0004385=NAS, GO:0042981=IEA, GO:0001819=IMP, GO:0005829=TAS, GO:0005622=IEA, GO:0007165=IEA, GO:0045086=IEA, GO:0005737=IDA, GO:0051092=IMP, GO:0042101=IDA, GO:0045061=IEA, GO:0042102=IEA, GO:0050776=IEA, GO:0045580=IEA, GO:0045121=IDA, GO:0043123=IEA} T cell costimulation, T cell receptor signaling pathway, positive regulation of B cell proliferation, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of T cell proliferation, positive regulation of cytokine production, positive regulation of interleukin-2 biosynthetic process, regulation of B cell differentiation, regulation of T cell differentiation, regulation of apoptotic process, regulation of immune response, signal transduction, thymic T cell selection T cell receptor complex, cytoplasm, cytosol, intracellular, membrane raft, plasma membrane CARD domain binding, guanylate kinase activity, protein binding Human CARD14 HPA UniProtKB {GO:0050700=PMID:11278692, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0005886=PMID:11278692, GO:0007250=PMID:11278692, GO:0016235=GO_REF:0000052, GO:0001934=PMID:11278692, GO:0042981=GO_REF:0000002} Q9BXL6 Caspase recruitment domain-containing protein 14 protein 20100326 {GO:0050700=IPI, GO:0005622=IEA, GO:0005737=IDA, GO:0005886=NAS, GO:0007250=NAS, GO:0016235=IDA, GO:0001934=IDA, GO:0042981=IEA} activation of NF-kappaB-inducing kinase activity, positive regulation of protein phosphorylation, regulation of apoptotic process aggresome, cytoplasm, intracellular, plasma membrane CARD domain binding Human CARD16 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0004869=GO_REF:0000037, GO:0042981=GO_REF:0000002} Q5EG05 Caspase recruitment domain-containing protein 16 protein 20130413 {GO:0005622=IEA, GO:0004869=IEA, GO:0042981=IEA} regulation of apoptotic process intracellular cysteine-type endopeptidase inhibitor activity Human UniProtKB-KW:KW-0789 CARD17 UniProtKB UniProtKB {GO:0004197=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0004869=GO_REF:0000037, GO:0006508=GO_REF:0000002, GO:0042981=GO_REF:0000002} Q5XLA6 Caspase recruitment domain-containing protein 17 protein 20130413 {GO:0004197=IEA, GO:0005737=IEA, GO:0004869=IEA, GO:0006508=IEA, GO:0042981=IEA} proteolysis, regulation of apoptotic process cytoplasm cysteine-type endopeptidase activity, cysteine-type endopeptidase inhibitor activity Human UniProtKB-SubCell:SL-0086 CARD18 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006954=PMID:11051551, GO:0004869=GO_REF:0000037, GO:0042981=GO_REF:0000002, GO:0005575=GO_REF:0000015} P57730 Caspase recruitment domain-containing protein 18 protein 20061026 {GO:0005622=IEA, GO:0006954=NAS, GO:0004869=IEA, GO:0042981=IEA, GO:0005575=ND} inflammatory response, regulation of apoptotic process cellular_component, intracellular cysteine-type endopeptidase inhibitor activity Human CARD6 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006915=GO_REF:0000037, GO:0042981=GO_REF:0000002} Q9BX69 Caspase recruitment domain-containing protein 6 protein 20130413 {GO:0005622=IEA, GO:0006915=IEA, GO:0042981=IEA} apoptotic process, regulation of apoptotic process intracellular Human UniProtKB-KW:KW-0053 CARD8 GOC UniProtKB {GO:0043280=PMID:15030775, GO:0005515=PMID:11551959, GO:0072559=PMID:15030775, GO:0005737=PMID:15030775, GO:0006919=PMID:15030775, GO:0050718=PMID:15030775, GO:0032089=PMID:15030775, GO:0005634=PMID:11551959, GO:0008656=PMID:15030775, GO:0042803=PMID:15030775, GO:0043124=PMID:11551959} Q9Y2G2 Caspase recruitment domain-containing protein 8 protein 20130413 {GO:0043280=IDA, GO:0005515=IPI, GO:0072559=IDA, GO:0005737=IDA, GO:0006919=IDA, GO:0050718=IDA, GO:0032089=IPI, GO:0005634=IDA, GO:0008656=IDA, GO:0042803=IDA, GO:0043124=IDA} activation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of interleukin-1 beta secretion NLRP3 inflammasome complex, cytoplasm, nucleus NACHT domain binding, cysteine-type endopeptidase activator activity involved in apoptotic process, protein binding, protein homodimerization activity Human CARD9 Reactome UniProtKB {GO:0050700=PMID:11053425, GO:0032755=GO_REF:0000019, GO:0032760=GO_REF:0000019, GO:0050830=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0042534=GO_REF:0000019, GO:0070423=Reactome:REACT_75776, GO:0046330=PMID:17187069, GO:0009620=GO_REF:0000019, GO:0032874=PMID:17187069, GO:0042981=GO_REF:0000002, GO:0045408=GO_REF:0000019, GO:0035872=Reactome:REACT_75913, GO:0042803=PMID:11053425, GO:0005737=PMID:11053425, GO:0051607=GO_REF:0000019, GO:0045076=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0032494=GO_REF:0000019, GO:0032495=GO_REF:0000019, GO:0043123=PMID:11053425, GO:0043330=GO_REF:0000019} Q9H257 Caspase recruitment domain-containing protein 9 protein 20100330 {GO:0050700=IPI, GO:0032755=IEA, GO:0032760=IEA, GO:0050830=IEA, GO:0042493=IEA, GO:0042534=IEA, GO:0070423=TAS, GO:0046330=IDA, GO:0009620=IEA, GO:0032874=IDA, GO:0042981=IEA, GO:0045408=IEA, GO:0035872=TAS, GO:0042803=IPI, GO:0005737=IDA, GO:0051607=IEA, GO:0045076=IEA, GO:0045087=TAS, GO:0032494=IEA, GO:0032495=IEA, GO:0043123=IEP, GO:0043330=IEA} defense response to Gram-positive bacterium, defense response to virus, innate immune response, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, nucleotide-binding oligomerization domain containing signaling pathway, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of JNK cascade, positive regulation of interleukin-6 production, positive regulation of stress-activated MAPK cascade, positive regulation of tumor necrosis factor production, regulation of apoptotic process, regulation of interleukin-2 biosynthetic process, regulation of interleukin-6 biosynthetic process, regulation of tumor necrosis factor biosynthetic process, response to drug, response to exogenous dsRNA, response to fungus, response to muramyl dipeptide, response to peptidoglycan cytoplasm CARD domain binding, protein homodimerization activity Human CARHSP1 PINC UniProtKB {GO:0035556=PMID:9712905, GO:0043488=GO_REF:0000024, GO:0005737=GO_REF:0000019, GO:0006355=GO_REF:0000002, GO:0019902=PMID:12801884, GO:0000932=GO_REF:0000039, GO:0000177=GO_REF:0000024, GO:0043186=GO_REF:0000024, GO:0003730=PMID:21078874, GO:0003677=GO_REF:0000002, GO:0005829=GO_REF:0000024} Q9Y2V2 Calcium-regulated heat stable protein 1 protein 20030904 {GO:0035556=TAS, GO:0043488=ISS, GO:0005737=IEA, GO:0006355=IEA, GO:0019902=NAS, GO:0000932=IEA, GO:0000177=ISS, GO:0043186=ISS, GO:0003730=IDA, GO:0003677=IEA, GO:0005829=ISS} intracellular signal transduction, regulation of mRNA stability, regulation of transcription, DNA-dependent P granule, cytoplasm, cytoplasmic exosome (RNase complex), cytoplasmic mRNA processing body, cytosol DNA binding, mRNA 3'-UTR binding, phosphatase binding Human CARKD UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0046496=GO_REF:0000020, GO:0047453=GO_REF:0000003, GO:0005524=GO_REF:0000037} Q8IW45 ATP-dependent (S)-NAD(P)H-hydrate dehydratase protein 20080829 {GO:0005739=IEA, GO:0008150=ND, GO:0003674=ND, GO:0005575=ND, GO:0046496=IEA, GO:0047453=IEA, GO:0005524=IEA} biological_process, nicotinamide nucleotide metabolic process cellular_component, mitochondrion ATP binding, ATP-dependent NAD(P)H-hydrate dehydratase activity, molecular_function Human CARM1 Reactome UniProtKB {GO:0032091=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0008013=PMID:16344550, GO:0044212=GO_REF:0000024, GO:0034971=GO_REF:0000024, GO:0008168=GO_REF:0000038, GO:0005634=PMID:15221992, GO:0044281=Reactome:REACT_111217, GO:0051591=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0042054=PMID:19405910, GO:0005829=GO_REF:0000024, GO:0005737=PMID:15221992, GO:0030374=GO_REF:0000024, GO:0060350=GO_REF:0000019, GO:0006479=GO_REF:0000002, GO:0070577=GO_REF:0000024, GO:0003420=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0006355=GO_REF:0000024, GO:0016571=PMID:19405910, GO:0003713=GO_REF:0000024, GO:0016274=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0035242=GO_REF:0000024, GO:0019048=GO_REF:0000037, GO:0033146=GO_REF:0000024, GO:0009405=GO_REF:0000002, GO:0045600=GO_REF:0000024, GO:0005654=Reactome:REACT_19175, GO:0035642=GO_REF:0000024, GO:0008276=GO_REF:0000024, GO:0030520=GO_REF:0000019, GO:0034970=PMID:17898714} Q86X55 Histone-arginine methyltransferase CARM1 protein 20130301 {GO:0032091=IEA, GO:0008284=IEA, GO:0008013=TAS, GO:0044212=ISS, GO:0034971=ISS, GO:0008168=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0051591=IEA, GO:0042803=IEA, GO:0042054=IDA, GO:0005829=ISS, GO:0005737=IDA, GO:0030374=ISS, GO:0060350=IEA, GO:0006479=IEA, GO:0070577=ISS, GO:0003420=IEA, GO:0044255=TAS, GO:0006355=ISS, GO:0016571=IDA, GO:0003713=ISS, GO:0016274=ISS, GO:0006351=IEA, GO:0035242=ISS, GO:0019048=IEA, GO:0033146=ISS, GO:0009405=IEA, GO:0045600=ISS, GO:0005654=TAS, GO:0035642=ISS, GO:0008276=ISS, GO:0030520=IEA, GO:0034970=IMP} cellular lipid metabolic process, endochondral bone morphogenesis, histone H3-R17 methylation, histone H3-R2 methylation, histone methylation, intracellular estrogen receptor signaling pathway, negative regulation of protein binding, pathogenesis, positive regulation of cell proliferation, positive regulation of fat cell differentiation, protein methylation, regulation of growth plate cartilage chondrocyte proliferation, regulation of intracellular estrogen receptor signaling pathway, regulation of transcription, DNA-dependent, response to cAMP, small molecule metabolic process, transcription, DNA-dependent, virus-host interaction cytoplasm, cytosol, nucleoplasm, nucleus beta-catenin binding, histone acetyl-lysine binding, histone methyltransferase activity, histone methyltransferase activity (H3-R17 specific), ligand-dependent nuclear receptor transcription coactivator activity, methyltransferase activity, protein homodimerization activity, protein methyltransferase activity, protein-arginine N-methyltransferase activity, protein-arginine omega-N asymmetric methyltransferase activity, transcription coactivator activity, transcription regulatory region DNA binding Human CARNS1 ENSEMBL UniProtKB {GO:0047730=GO_REF:0000019, GO:0006200=PMID:20097752, GO:0035499=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0016887=GO_REF:0000019, GO:0005524=GO_REF:0000002, GO:0046872=GO_REF:0000002} F5H427 Carnosine synthase 1 protein 20130413 {GO:0047730=IEA, GO:0006200=IDA, GO:0035499=IEA, GO:0005575=ND, GO:0016887=IEA, GO:0005524=IEA, GO:0046872=IEA} ATP catabolic process, carnosine biosynthetic process cellular_component ATP binding, ATPase activity, carnosine synthase activity, metal ion binding Human Ensembl:ENSMUSP00000131624 CARS HPA UniProtKB {GO:0005515=PMID:10908348, GO:0006423=PMID:10908348, GO:0010467=Reactome:REACT_71, GO:0005737=GO_REF:0000052, GO:0000049=PMID:7987009, GO:0004817=Reactome:REACT_15527, GO:0005524=PMID:17303165, GO:0042803=PMID:17303165, GO:0046872=GO_REF:0000037, GO:0006418=Reactome:REACT_15482, GO:0005829=Reactome:REACT_15527} P49589 Cysteine--tRNA ligase, cytoplasmic protein 20080205 {GO:0005515=IPI, GO:0006423=IDA, GO:0010467=TAS, GO:0005737=IDA, GO:0000049=NAS, GO:0004817=TAS, GO:0005524=IDA, GO:0042803=IMP, GO:0046872=IEA, GO:0006418=TAS, GO:0005829=TAS} cysteinyl-tRNA aminoacylation, gene expression, tRNA aminoacylation for protein translation cytoplasm, cytosol ATP binding, cysteine-tRNA ligase activity, metal ion binding, protein binding, protein homodimerization activity, tRNA binding Human CARS2 Reactome UniProtKB {GO:0006423=GO_REF:0000033, GO:0010467=Reactome:REACT_71, GO:0004817=GO_REF:0000033, GO:0005759=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0006418=Reactome:REACT_15482, GO:0005829=GO_REF:0000033} Q9HA77 Probable cysteine--tRNA ligase, mitochondrial protein 20130301 {GO:0006423=IBA, GO:0010467=TAS, GO:0004817=IBA, GO:0005759=IEA, GO:0005524=IEA, GO:0046872=IEA, GO:0006418=TAS, GO:0005829=IBA} cysteinyl-tRNA aminoacylation, gene expression, tRNA aminoacylation for protein translation cytosol, mitochondrial matrix ATP binding, cysteine-tRNA ligase activity, metal ion binding Human CASC1 ENSEMBL UniProtKB {GO:0008017=GO_REF:0000019, GO:0005881=GO_REF:0000019, GO:0048487=GO_REF:0000019} G3V3G6 Cancer susceptibility candidate protein 1 protein 20130413 {GO:0008017=IEA, GO:0005881=IEA, GO:0048487=IEA} cytoplasmic microtubule beta-tubulin binding, microtubule binding Human Ensembl:ENSMUSP00000062279 CASC3 HPA UniProtKB {GO:0005515=PMID:23084401, GO:0006397=GO_REF:0000037, GO:0008380=GO_REF:0000037, GO:0010467=Reactome:REACT_71, GO:0048471=GO_REF:0000039, GO:0008298=GO_REF:0000019, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0006950=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0006417=GO_REF:0000037, GO:0005829=Reactome:REACT_75910, GO:0042802=PMID:12080473, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0000184=Reactome:REACT_75886, GO:0016607=GO_REF:0000039, GO:0030529=GO_REF:0000019, GO:0051028=GO_REF:0000037, GO:0019899=PMID:21478859, GO:0031625=PMID:21478859, GO:0035145=PMID:16601204} O15234 Protein CASC3 protein 20101115 {GO:0005515=IPI, GO:0006397=IEA, GO:0008380=IEA, GO:0010467=TAS, GO:0048471=IEA, GO:0008298=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=IEA, GO:0005730=IDA, GO:0006950=IEA, GO:0005634=IDA, GO:0006417=IEA, GO:0005829=TAS, GO:0042802=IDA, GO:0008150=ND, GO:0005737=IDA, GO:0000184=TAS, GO:0016607=IEA, GO:0030529=IEA, GO:0051028=IEA, GO:0019899=IPI, GO:0031625=IPI, GO:0035145=IDA} RNA metabolic process, RNA splicing, biological_process, gene expression, intracellular mRNA localization, mRNA metabolic process, mRNA processing, mRNA transport, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, regulation of translation, response to stress cytoplasm, cytosol, exon-exon junction complex, nuclear speck, nucleolus, nucleus, perinuclear region of cytoplasm, ribonucleoprotein complex RNA binding, enzyme binding, identical protein binding, protein binding, ubiquitin protein ligase binding Human CASC4 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q6P4E1 Protein CASC4 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 CASC5 HPA UniProtKB {GO:0005515=PMID:17981135, GO:0000236=Reactome:REACT_682, GO:0001675=PMID:15579588, GO:0001669=PMID:15579588, GO:0034501=PMID:22331848, GO:0006334=Reactome:REACT_22344, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005829=Reactome:REACT_150414, GO:0034080=Reactome:REACT_22186, GO:0010923=PMID:19389623, GO:0000087=Reactome:REACT_910, GO:0000777=GO_REF:0000039, GO:0071173=PMID:17981135, GO:0005654=Reactome:REACT_22217, GO:0000278=Reactome:REACT_152, GO:0008608=PMID:17981135, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q8NG31 Protein CASC5 protein 20111111 {GO:0005515=IPI, GO:0000236=TAS, GO:0001675=NAS, GO:0001669=IDA, GO:0034501=IDA, GO:0006334=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0005829=TAS, GO:0034080=TAS, GO:0010923=IDA, GO:0000087=TAS, GO:0000777=IEA, GO:0071173=IDA, GO:0005654=TAS, GO:0000278=TAS, GO:0008608=IDA, GO:0000090=TAS, GO:0051301=IEA} CENP-A containing nucleosome assembly at centromere, M phase of mitotic cell cycle, acrosome assembly, attachment of spindle microtubules to kinetochore, cell division, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, negative regulation of phosphatase activity, nucleosome assembly, protein localization to kinetochore, spindle assembly checkpoint acrosomal vesicle, condensed chromosome kinetochore, cytosol, nucleolus, nucleoplasm, nucleus protein binding NOT Human CASD1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q96PB1 CAS1 domain-containing protein 1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 CASK InterPro UniProtKB {GO:0005515=PMID:15694377, GO:0010839=PMID:18664494, GO:0005516=GO_REF:0000037, GO:0060170=GO_REF:0000024, GO:0005886=PMID:9660868, GO:0090288=PMID:18664494, GO:0015629=PMID:9660868, GO:0090280=GO_REF:0000019, GO:0016363=PMID:18664494, GO:0005829=GO_REF:0000019, GO:0016323=GO_REF:0000019, GO:0005737=PMID:18664494, GO:0061045=PMID:18664494, GO:0005911=PMID:18664494, GO:0045944=GO_REF:0000019, GO:0007155=PMID:9660868, GO:0005730=PMID:18664494, GO:0004385=PMID:9660868, GO:0042043=GO_REF:0000019, GO:0005524=GO_REF:0000002, GO:0005604=PMID:18664494, GO:0042734=GO_REF:0000024, GO:0070509=GO_REF:0000019, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000037, GO:0005652=PMID:18664494, GO:0001953=PMID:18664494} Q5JS74 Peripheral plasma membrane protein CASK protein 20130413 {GO:0005515=IPI, GO:0010839=IMP, GO:0005516=IEA, GO:0060170=ISS, GO:0005886=TAS, GO:0090288=IMP, GO:0015629=TAS, GO:0090280=IEA, GO:0016363=IDA, GO:0005829=IEA, GO:0016323=IEA, GO:0005737=IDA, GO:0061045=IMP, GO:0005911=IDA, GO:0045944=IEA, GO:0007155=TAS, GO:0005730=IDA, GO:0004385=TAS, GO:0042043=IEA, GO:0005524=IEA, GO:0005604=IDA, GO:0042734=ISS, GO:0070509=IEA, GO:0004672=IEA, GO:0004674=IEA, GO:0005652=IDA, GO:0001953=IMP} calcium ion import, cell adhesion, negative regulation of cell-matrix adhesion, negative regulation of cellular response to growth factor stimulus, negative regulation of keratinocyte proliferation, negative regulation of wound healing, positive regulation of calcium ion import, positive regulation of transcription from RNA polymerase II promoter actin cytoskeleton, basement membrane, basolateral plasma membrane, cell-cell junction, cilium membrane, cytoplasm, cytosol, nuclear lamina, nuclear matrix, nucleolus, plasma membrane, presynaptic membrane ATP binding, calmodulin binding, guanylate kinase activity, neurexin family protein binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human InterPro:IPR000719|InterPro:IPR002290 CASKIN1 UniProtKB UniProtKB {GO:0007165=PMID:12040031, GO:0005737=PMID:12040031} Q8WXD9 Caskin-1 protein 20050408 {GO:0007165=ISS, GO:0005737=ISS} signal transduction cytoplasm Human UniProtKB:Q8VHK2 CASKIN2 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005737=PMID:12040031} Q8WXE0 Caskin-2 protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0005737=ISS} biological_process cytoplasm molecular_function Human CASP1 InterPro UniProtKB {GO:0005515=PMID:18329368, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_75834, GO:0005622=GO_REF:0000002, GO:0050717=GO_REF:0000019, GO:0050718=GO_REF:0000019, GO:0016485=GO_REF:0000019, GO:0006508=PMID:12888622, GO:0033198=GO_REF:0000019, GO:0043123=PMID:12761501, GO:0072559=PMID:15030775, GO:0001666=GO_REF:0000019, GO:0006919=PMID:10799503, GO:0072557=GO_REF:0000024, GO:0071310=PMID:19158679, GO:0072558=PMID:12191486, GO:0006915=PMID:7876192, GO:0005576=GO_REF:0000019, GO:0042981=GO_REF:0000002, GO:0006917=GO_REF:0000019, GO:0008656=PMID:10799503, GO:0004197=Reactome:REACT_23804, GO:0007165=PMID:1373520, GO:0045087=Reactome:REACT_6802, GO:0032611=GO_REF:0000019, GO:0071260=PMID:19593445, GO:0097169=PMID:19158676} Q5FBZ0 Caspase-1 subunit p20 protein 20130413 {GO:0005515=IPI, GO:0035872=TAS, GO:0005829=TAS, GO:0005622=IEA, GO:0050717=IEA, GO:0050718=IEA, GO:0016485=IEA, GO:0006508=IDA, GO:0033198=IEA, GO:0043123=IEP, GO:0072559=IDA, GO:0001666=IEA, GO:0006919=TAS, GO:0072557=ISS, GO:0071310=IDA, GO:0072558=IDA, GO:0006915=TAS, GO:0005576=IEA, GO:0042981=IEA, GO:0006917=IEA, GO:0008656=TAS, GO:0004197=TAS, GO:0007165=TAS, GO:0045087=TAS, GO:0032611=IEA, GO:0071260=IEP, GO:0097169=IDA} activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, cellular response to mechanical stimulus, cellular response to organic substance, induction of apoptosis, innate immune response, interleukin-1 beta production, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of interleukin-1 alpha secretion, positive regulation of interleukin-1 beta secretion, protein processing, proteolysis, regulation of apoptotic process, response to ATP, response to hypoxia, signal transduction AIM2 inflammasome complex, IPAF inflammasome complex, NLRP1 inflammasome complex, NLRP3 inflammasome complex, cytosol, extracellular region, intracellular cysteine-type endopeptidase activator activity involved in apoptotic process, cysteine-type endopeptidase activity, protein binding Human InterPro:IPR001315 CASP10 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0004197=GO_REF:0000002, GO:0005886=Reactome:REACT_1418, GO:0045087=Reactome:REACT_6802, GO:0006508=GO_REF:0000037, GO:0006915=Reactome:REACT_578, GO:0042981=GO_REF:0000002, GO:0006917=PMID:10412980, GO:0043123=PMID:19641626, GO:0097190=Reactome:REACT_1619, GO:0005829=Reactome:REACT_25167} Q92851 Caspase-10 protein 20130415 {GO:0005515=IPI, GO:0004197=IEA, GO:0005886=TAS, GO:0045087=TAS, GO:0006508=IEA, GO:0006915=TAS, GO:0042981=IEA, GO:0006917=TAS, GO:0043123=RCA, GO:0097190=TAS, GO:0005829=TAS} apoptotic process, apoptotic signaling pathway, induction of apoptosis, innate immune response, positive regulation of I-kappaB kinase/NF-kappaB cascade, proteolysis, regulation of apoptotic process cytosol, plasma membrane cysteine-type endopeptidase activity, protein binding Human UniProtKB:O14730 CASP12 ENSEMBL UniProtKB {GO:0005622=GO_REF:0000002, GO:0004197=GO_REF:0000002, GO:0070059=GO_REF:0000019, GO:0006508=GO_REF:0000002, GO:0006915=GO_REF:0000002, GO:0042981=GO_REF:0000002, GO:0006926=GO_REF:0000019, GO:0030968=GO_REF:0000019} Q6UXS9 Inactive caspase-12 protein 20130413 {GO:0005622=IEA, GO:0004197=IEA, GO:0070059=IEA, GO:0006508=IEA, GO:0006915=IEA, GO:0042981=IEA, GO:0006926=IEA, GO:0030968=IEA} apoptotic process, endoplasmic reticulum unfolded protein response, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, proteolysis, regulation of apoptotic process, virus-infected cell apoptotic process intracellular cysteine-type endopeptidase activity Human Ensembl:ENSMUSP00000027009 CASP14 PINC UniProtKB {GO:0004197=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0008544=PMID:10203698, GO:0006508=GO_REF:0000037, GO:0006915=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0045095=GO_REF:0000019, GO:0030154=GO_REF:0000037} P31944 Caspase-14 protein 20030904 {GO:0004197=IEA, GO:0005737=IEA, GO:0008544=TAS, GO:0006508=IEA, GO:0006915=IEA, GO:0005634=IEA, GO:0045095=IEA, GO:0030154=IEA} apoptotic process, cell differentiation, epidermis development, proteolysis cytoplasm, keratin filament, nucleus cysteine-type endopeptidase activity Human CASP2 BHF-UCL UniProtKB {GO:0005515=PMID:16652156, GO:0048011=Reactome:REACT_13776, GO:0043065=PMID:10980123, GO:0003407=GO_REF:0000019, GO:0019904=PMID:9044836, GO:0007568=GO_REF:0000019, GO:0097194=PMID:18309324, GO:0006915=Reactome:REACT_13526, GO:0001554=GO_REF:0000019, GO:0042981=GO_REF:0000002, GO:0005634=GO_REF:0000019, GO:0006917=GO_REF:0000019, GO:0097190=Reactome:REACT_13720, GO:0005829=Reactome:REACT_13533, GO:0004197=PMID:9044836, GO:0005622=GO_REF:0000002, GO:0005739=GO_REF:0000019, GO:0043525=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0016485=PMID:9044836, GO:0007420=GO_REF:0000019, GO:0006508=GO_REF:0000037, GO:0071260=PMID:19593445, GO:0019899=PMID:11076957} P42575 Caspase-2 protein 20090323 {GO:0005515=IPI, GO:0048011=TAS, GO:0043065=IDA, GO:0003407=IEA, GO:0019904=IPI, GO:0007568=IEA, GO:0097194=TAS, GO:0006915=TAS, GO:0001554=IEA, GO:0042981=IEA, GO:0005634=IEA, GO:0006917=IEA, GO:0097190=TAS, GO:0005829=TAS, GO:0004197=IDA, GO:0005622=IEA, GO:0005739=IEA, GO:0043525=IEA, GO:0016020=IEA, GO:0016485=IDA, GO:0007420=IEA, GO:0006508=IEA, GO:0071260=IEP, GO:0019899=ISS} aging, apoptotic process, apoptotic signaling pathway, brain development, cellular response to mechanical stimulus, execution phase of apoptosis, induction of apoptosis, luteolysis, neural retina development, neurotrophin TRK receptor signaling pathway, positive regulation of apoptotic process, positive regulation of neuron apoptotic process, protein processing, proteolysis, regulation of apoptotic process cytosol, intracellular, membrane, mitochondrion, nucleus cysteine-type endopeptidase activity, enzyme binding, protein binding, protein domain specific binding Human UniProtKB:P78560 CASP3 HPA UniProtKB {GO:0005515=PMID:17823127, GO:0008625=GO_REF:0000019, GO:0001782=GO_REF:0000019, GO:0005886=Reactome:REACT_13598, GO:0045736=GO_REF:0000019, GO:0007605=GO_REF:0000019, GO:0046007=GO_REF:0000019, GO:0001836=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0051402=GO_REF:0000019, GO:0006921=Reactome:REACT_995, GO:0005829=PMID:17823127, GO:0005739=GO_REF:0000052, GO:0007507=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0043525=GO_REF:0000019, GO:0016485=GO_REF:0000019, GO:0006508=PMID:12888622, GO:0043029=GO_REF:0000019, GO:0009411=GO_REF:0000019, GO:0048011=Reactome:REACT_13776, GO:0043066=PMID:9353287, GO:0008635=Reactome:REACT_607, GO:0071310=GO_REF:0000019, GO:0008631=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0009611=GO_REF:0000019, GO:0006915=Reactome:REACT_13526, GO:0030889=GO_REF:0000019, GO:0042981=Reactome:REACT_13648, GO:0035329=Reactome:REACT_118607, GO:0006917=GO_REF:0000019, GO:0097190=PMID:10521396, GO:0097193=Reactome:REACT_964, GO:0006974=GO_REF:0000019, GO:0004197=Reactome:REACT_13598, GO:0045165=GO_REF:0000019, GO:0006309=Reactome:REACT_1213, GO:0030216=GO_REF:0000019, GO:0004861=GO_REF:0000019, GO:0030264=PMID:11350920, GO:0034612=PMID:10521396, GO:0005654=Reactome:REACT_13508, GO:0008233=PMID:9353287, GO:0004190=Reactome:REACT_22440} P42574 Caspase-3 protein 20080205 {GO:0005515=IPI, GO:0008625=IEA, GO:0001782=IEA, GO:0005886=TAS, GO:0045736=IEA, GO:0007605=IEA, GO:0046007=IEA, GO:0001836=IEA, GO:0005634=IDA, GO:0051402=IEA, GO:0006921=TAS, GO:0005829=IDA, GO:0005739=IDA, GO:0007507=IEA, GO:0005737=IDA, GO:0043525=IEA, GO:0016485=IEA, GO:0006508=IDA, GO:0043029=IEA, GO:0009411=IEA, GO:0048011=TAS, GO:0043066=IGI, GO:0008635=TAS, GO:0071310=IEA, GO:0008631=IEA, GO:0005730=IDA, GO:0009611=IEA, GO:0006915=TAS, GO:0030889=IEA, GO:0042981=TAS, GO:0035329=TAS, GO:0006917=IEA, GO:0097190=TAS, GO:0097193=TAS, GO:0006974=IEA, GO:0004197=TAS, GO:0045165=IEA, GO:0006309=TAS, GO:0030216=IEA, GO:0004861=IEA, GO:0030264=IMP, GO:0034612=TAS, GO:0005654=TAS, GO:0008233=IDA, GO:0004190=EXP} B cell homeostasis, T cell homeostasis, activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c, apoptotic DNA fragmentation, apoptotic process, apoptotic signaling pathway, cell fate commitment, cellular component disassembly involved in execution phase of apoptosis, cellular response to organic substance, extrinsic apoptotic signaling pathway via death domain receptors, heart development, hippo signaling cascade, induction of apoptosis, intrinsic apoptotic signaling pathway, intrinsic apoptotic signaling pathway in response to oxidative stress, keratinocyte differentiation, negative regulation of B cell proliferation, negative regulation of activated T cell proliferation, negative regulation of apoptotic process, negative regulation of cyclin-dependent protein serine/threonine kinase activity, neuron apoptotic process, neurotrophin TRK receptor signaling pathway, nuclear fragmentation involved in apoptotic nuclear change, positive regulation of neuron apoptotic process, protein processing, proteolysis, regulation of apoptotic process, release of cytochrome c from mitochondria, response to DNA damage stimulus, response to UV, response to tumor necrosis factor, response to wounding, sensory perception of sound cytoplasm, cytosol, mitochondrion, nucleolus, nucleoplasm, nucleus, plasma membrane aspartic-type endopeptidase activity, cyclin-dependent protein serine/threonine kinase inhibitor activity, cysteine-type endopeptidase activity, peptidase activity, protein binding Human CASP4 PINC UniProtKB {GO:0005622=GO_REF:0000002, GO:0004197=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0006915=GO_REF:0000037, GO:0042981=GO_REF:0000002, GO:0006917=PMID:7743998} P49662 Caspase-4 protein 20030904 {GO:0005622=IEA, GO:0004197=IEA, GO:0006508=IEA, GO:0006915=IEA, GO:0042981=IEA, GO:0006917=TAS} apoptotic process, induction of apoptosis, proteolysis, regulation of apoptotic process intracellular cysteine-type endopeptidase activity Human CASP5 PINC UniProtKB {GO:0005622=GO_REF:0000002, GO:0004197=GO_REF:0000002, GO:0072558=PMID:12191486, GO:0006508=GO_REF:0000037, GO:0006915=GO_REF:0000037, GO:0042981=GO_REF:0000002, GO:0008234=PMID:7797592, GO:0071260=PMID:19593445} P51878 Caspase-5 protein 20030904 {GO:0005622=IEA, GO:0004197=IEA, GO:0072558=IDA, GO:0006508=IEA, GO:0006915=IEA, GO:0042981=IEA, GO:0008234=TAS, GO:0071260=IEP} apoptotic process, cellular response to mechanical stimulus, proteolysis, regulation of apoptotic process NLRP1 inflammasome complex, intracellular cysteine-type endopeptidase activity, cysteine-type peptidase activity Human CASP6 HPA UniProtKB {GO:0005515=PMID:18408014, GO:0004197=Reactome:REACT_22225, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0006508=PMID:12888622, GO:0006915=Reactome:REACT_578, GO:0005634=GO_REF:0000052, GO:0005654=Reactome:REACT_22225, GO:0008234=PMID:7796396, GO:0006917=PMID:7796396, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_13519} P55212 Caspase-6 protein 20120912 {GO:0005515=IPI, GO:0004197=TAS, GO:0005737=IDA, GO:0005730=IDA, GO:0006508=IDA, GO:0006915=TAS, GO:0005634=IDA, GO:0005654=TAS, GO:0008234=TAS, GO:0006917=TAS, GO:0006921=TAS, GO:0005829=TAS} apoptotic process, cellular component disassembly involved in execution phase of apoptosis, induction of apoptosis, proteolysis cytoplasm, cytosol, nucleolus, nucleoplasm, nucleus cysteine-type endopeptidase activity, cysteine-type peptidase activity, protein binding Human CASP7 ENSEMBL UniProtKB {GO:0005515=PMID:11257231, GO:0008635=Reactome:REACT_607, GO:0006915=GO_REF:0000002, GO:0001836=GO_REF:0000019, GO:0006917=GO_REF:0000019, GO:0097193=Reactome:REACT_964, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_13428, GO:0007507=GO_REF:0000019, GO:0004197=GO_REF:0000019, GO:0005737=GO_REF:0000002, GO:0043525=GO_REF:0000019, GO:0016485=GO_REF:0000019, GO:0006508=GO_REF:0000002, GO:0005654=Reactome:REACT_13652, GO:0004190=GO_REF:0000019, GO:0008234=PMID:8567622, GO:0009411=GO_REF:0000019} Q5SVL2 Caspase-7 protein 20130413 {GO:0005515=IPI, GO:0008635=TAS, GO:0006915=IEA, GO:0001836=IEA, GO:0006917=IEA, GO:0097193=TAS, GO:0006921=TAS, GO:0005829=TAS, GO:0007507=IEA, GO:0004197=IEA, GO:0005737=IEA, GO:0043525=IEA, GO:0016485=IEA, GO:0006508=IEA, GO:0005654=TAS, GO:0004190=IEA, GO:0008234=TAS, GO:0009411=IEA} activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c, apoptotic process, cellular component disassembly involved in execution phase of apoptosis, heart development, induction of apoptosis, intrinsic apoptotic signaling pathway, positive regulation of neuron apoptotic process, protein processing, proteolysis, release of cytochrome c from mitochondria, response to UV cytoplasm, cytosol, nucleoplasm aspartic-type endopeptidase activity, cysteine-type endopeptidase activity, cysteine-type peptidase activity, protein binding Human Ensembl:ENSMUSP00000026062 CASP8 BHF-UCL UniProtKB {GO:0005515=PMID:22274400, GO:0031265=GO_REF:0000019, GO:0009409=GO_REF:0000019, GO:0031264=PMID:11101870, GO:0097202=PMID:18387192, GO:0042802=PMID:16169070, GO:0007507=GO_REF:0000019, GO:0002756=Reactome:REACT_6809, GO:1900740=Reactome:REACT_701, GO:0051603=PMID:10521396, GO:0032496=GO_REF:0000019, GO:0006508=PMID:12888622, GO:0032025=GO_REF:0000019, GO:0043123=PMID:12761501, GO:0005856=PMID:10891503, GO:0032355=GO_REF:0000019, GO:0046677=GO_REF:0000019, GO:0005164=GO_REF:0000019, GO:0005813=GO_REF:0000052, GO:0030690=GO_REF:0000019, GO:0002224=Reactome:REACT_6966, GO:0001841=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0045121=GO_REF:0000019, GO:0035666=Reactome:REACT_25281, GO:0008234=PMID:8681376, GO:0043005=GO_REF:0000019, GO:0034142=Reactome:REACT_6894, GO:0045471=GO_REF:0000019, GO:0070423=Reactome:REACT_75776, GO:0005741=Reactome:REACT_13713, GO:0005634=GO_REF:0000052, GO:0051291=GO_REF:0000019, GO:0006921=Reactome:REACT_995, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_150447, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0030225=GO_REF:0000019, GO:0034138=Reactome:REACT_6783, GO:0006919=Reactome:REACT_1503, GO:0005730=GO_REF:0000052, GO:0006915=Reactome:REACT_578, GO:0042981=GO_REF:0000002, GO:0001525=GO_REF:0000019, GO:0097191=PMID:21785459, GO:0097190=PMID:11101870, GO:0044297=GO_REF:0000019, GO:0097193=Reactome:REACT_964, GO:0045862=PMID:18387192, GO:0004197=Reactome:REACT_150381, GO:0019048=GO_REF:0000037, GO:0034612=PMID:10521396, GO:0071260=PMID:19593445} Q14790 Caspase-8 protein 20130219 {GO:0005515=IPI, GO:0031265=IEA, GO:0009409=IEA, GO:0031264=IDA, GO:0097202=IDA, GO:0042802=IPI, GO:0007507=IEA, GO:0002756=TAS, GO:1900740=TAS, GO:0051603=IMP, GO:0032496=IEA, GO:0006508=IDA, GO:0032025=IEA, GO:0043123=IEP, GO:0005856=TAS, GO:0032355=IEA, GO:0046677=IEA, GO:0005164=IEA, GO:0005813=IDA, GO:0030690=IEA, GO:0002224=TAS, GO:0001841=IEA, GO:0045087=TAS, GO:0045121=IEA, GO:0035666=TAS, GO:0008234=TAS, GO:0043005=IEA, GO:0034142=TAS, GO:0045471=IEA, GO:0070423=TAS, GO:0005741=TAS, GO:0005634=IDA, GO:0051291=IEA, GO:0006921=TAS, GO:0035872=TAS, GO:0005829=TAS, GO:0005739=IDA, GO:0005737=IDA, GO:0030225=IEA, GO:0034138=TAS, GO:0006919=TAS, GO:0005730=IDA, GO:0006915=TAS, GO:0042981=IEA, GO:0001525=IEA, GO:0097191=IDA, GO:0097190=IMP, GO:0044297=IEA, GO:0097193=TAS, GO:0045862=IDA, GO:0004197=TAS, GO:0019048=IEA, GO:0034612=IMP, GO:0071260=IEP} MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, activation of cysteine-type endopeptidase activity, activation of cysteine-type endopeptidase activity involved in apoptotic process, angiogenesis, apoptotic process, apoptotic signaling pathway, cellular component disassembly involved in execution phase of apoptosis, cellular response to mechanical stimulus, extrinsic apoptotic signaling pathway, heart development, innate immune response, intrinsic apoptotic signaling pathway, macrophage differentiation, neural tube formation, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, nucleotide-binding oligomerization domain containing signaling pathway, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, positive regulation of proteolysis, protein heterooligomerization, proteolysis, proteolysis involved in cellular protein catabolic process, regulation of apoptotic process, response to antibiotic, response to cobalt ion, response to cold, response to estradiol stimulus, response to ethanol, response to lipopolysaccharide, response to tumor necrosis factor, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor signaling pathway, virus-host interaction CD95 death-inducing signaling complex, Noc1p-Noc2p complex, cell body, centrosome, cytoplasm, cytoskeleton, cytosol, death-inducing signaling complex, membrane raft, mitochondrial outer membrane, mitochondrion, neuron projection, nucleolus, nucleus cysteine-type endopeptidase activity, cysteine-type peptidase activity, identical protein binding, protein binding, tumor necrosis factor receptor binding Human CASP8AP2 IntAct UniProtKB {GO:0005515=PMID:21338522, GO:0008625=PMID:17245429, GO:0006355=GO_REF:0000037, GO:0032184=PMID:23086935, GO:0006919=PMID:17245429, GO:0003714=PMID:12477726, GO:0005634=PMID:12477726, GO:0005123=PMID:10235259, GO:0097190=PMID:10235259, GO:0003677=GO_REF:0000002, GO:0008656=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0005739=PMID:17245429, GO:0036337=PMID:17245429, GO:0016505=GO_REF:0000024, GO:0007165=PMID:10235259, GO:0007049=GO_REF:0000037, GO:0005737=PMID:17245429, GO:0016605=PMID:17245429, GO:0071260=PMID:19593445} Q9UKL3 CASP8-associated protein 2 protein 20130415 {GO:0005515=IPI, GO:0008625=IMP, GO:0006355=IEA, GO:0032184=IDA, GO:0006919=IMP, GO:0003714=IDA, GO:0005634=IDA, GO:0005123=TAS, GO:0097190=TAS, GO:0003677=IEA, GO:0008656=ISS, GO:0006351=IEA, GO:0005739=IDA, GO:0036337=IMP, GO:0016505=ISS, GO:0007165=TAS, GO:0007049=IEA, GO:0005737=IDA, GO:0016605=IDA, GO:0071260=IEP} Fas signaling pathway, activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic signaling pathway, cell cycle, cellular response to mechanical stimulus, extrinsic apoptotic signaling pathway via death domain receptors, regulation of transcription, DNA-dependent, signal transduction, transcription, DNA-dependent PML body, cytoplasm, mitochondrion, nucleus DNA binding, SUMO polymer binding, apoptotic protease activator activity, cysteine-type endopeptidase activator activity involved in apoptotic process, death receptor binding, protein binding, transcription corepressor activity Human UniProtKB:O75925 CASP9 InterPro UniProtKB {GO:0005515=PMID:18022362, GO:0017124=PMID:15657060, GO:2001020=PMID:15657060, GO:0005634=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0005622=GO_REF:0000002, GO:0034644=PMID:15657060, GO:0043525=GO_REF:0000019, GO:0043293=PMID:21827945, GO:0007173=Reactome:REACT_9417, GO:0006508=GO_REF:0000002, GO:0009411=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0008635=Reactome:REACT_607, GO:0019901=PMID:15657060, GO:0008630=PMID:15657060, GO:0006919=GO_REF:0000019, GO:0048015=Reactome:REACT_12464, GO:0006915=GO_REF:0000002, GO:0042981=GO_REF:0000002, GO:0097193=Reactome:REACT_964, GO:0006974=GO_REF:0000019, GO:0004197=GO_REF:0000002, GO:0042770=PMID:15657060, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0008233=PMID:20663920, GO:0008047=PMID:9390557, GO:0071549=GO_REF:0000019} Q5JRU8 Caspase-9 subunit p35 protein 20130413 {GO:0005515=IPI, GO:0017124=IDA, GO:2001020=IMP, GO:0005634=IEA, GO:0005829=IEA, GO:0005622=IEA, GO:0034644=IDA, GO:0043525=IEA, GO:0043293=IDA, GO:0007173=TAS, GO:0006508=IEA, GO:0009411=IEA, GO:0048011=TAS, GO:0008635=TAS, GO:0019901=IDA, GO:0008630=IMP, GO:0006919=IEA, GO:0048015=TAS, GO:0006915=IEA, GO:0042981=IEA, GO:0097193=TAS, GO:0006974=IEA, GO:0004197=IEA, GO:0042770=IDA, GO:0008543=TAS, GO:0045087=TAS, GO:0008233=IDA, GO:0008047=TAS, GO:0071549=IEA} activation of cysteine-type endopeptidase activity involved in apoptotic process, activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c, apoptotic process, cellular response to UV, cellular response to dexamethasone stimulus, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, intrinsic apoptotic signaling pathway, intrinsic apoptotic signaling pathway in response to DNA damage, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of neuron apoptotic process, proteolysis, regulation of apoptotic process, regulation of response to DNA damage stimulus, response to DNA damage stimulus, response to UV, signal transduction in response to DNA damage apoptosome, cytosol, intracellular, nucleus SH3 domain binding, cysteine-type endopeptidase activity, enzyme activator activity, peptidase activity, protein binding, protein kinase binding Human InterPro:IPR001315 CASQ1 Reactome UniProtKB {GO:0005794=GO_REF:0000019, GO:0010033=GO_REF:0000019, GO:0009408=GO_REF:0000019, GO:0005783=PMID:7945294, GO:0014804=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0033017=Reactome:REACT_160216, GO:0030315=GO_REF:0000019, GO:0014894=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0014809=GO_REF:0000019, GO:0005790=PMID:7945294, GO:0005739=GO_REF:0000019, GO:0034220=Reactome:REACT_25300, GO:0007519=GO_REF:0000019, GO:0005759=PMID:7945294, GO:0007029=GO_REF:0000019, GO:0051282=GO_REF:0000019, GO:0031674=GO_REF:0000019} P31415 Calsequestrin-1 protein 20130301 {GO:0005794=IEA, GO:0010033=IEA, GO:0009408=IEA, GO:0005783=NAS, GO:0014804=IEA, GO:0005509=IEA, GO:0033017=TAS, GO:0030315=IEA, GO:0014894=IEA, GO:0055085=TAS, GO:0014809=IEA, GO:0005790=TAS, GO:0005739=IEA, GO:0034220=TAS, GO:0007519=IEA, GO:0005759=TAS, GO:0007029=IEA, GO:0051282=IEA, GO:0031674=IEA} endoplasmic reticulum organization, ion transmembrane transport, regulation of sequestering of calcium ion, regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion, response to denervation involved in regulation of muscle adaptation, response to heat, response to organic substance, skeletal muscle tissue development, transmembrane transport Golgi apparatus, I band, T-tubule, endoplasmic reticulum, mitochondrial matrix, mitochondrion, sarcoplasmic reticulum membrane, smooth endoplasmic reticulum, terminal cisterna lumen calcium ion binding Human CASQ2 BHF-UCL UniProtKB {GO:0005515=PMID:22123818, GO:0005513=PMID:22123818, GO:0051258=PMID:22123818, GO:0051208=PMID:16601229, GO:0005509=PMID:16601229, GO:0060306=PMID:21063088, GO:0043267=PMID:21063088, GO:0006941=PMID:9795116, GO:0033018=PMID:16908766, GO:0071313=PMID:16908766, GO:0010881=PMID:16601229, GO:0033017=Reactome:REACT_160216, GO:0034704=PMID:19403607, GO:0055085=Reactome:REACT_15518, GO:0005891=GO_REF:0000024, GO:0042803=GO_REF:0000024, GO:0005622=PMID:16908766, GO:0014701=PMID:17569730, GO:0005737=PMID:22123818, GO:0034220=Reactome:REACT_25300, GO:0002027=PMID:16601229, GO:0010880=GO_REF:0000024, GO:0060315=PMID:16601229, GO:0086029=PMID:22198169} O14958 Calsequestrin-2 protein 20130218 {GO:0005515=IPI, GO:0005513=TAS, GO:0051258=IDA, GO:0051208=IDA, GO:0005509=IDA, GO:0060306=ISS, GO:0043267=ISS, GO:0006941=TAS, GO:0033018=IC, GO:0071313=IMP, GO:0010881=IMP, GO:0033017=TAS, GO:0034704=TAS, GO:0055085=TAS, GO:0005891=ISS, GO:0042803=ISS, GO:0005622=IMP, GO:0014701=TAS, GO:0005737=IDA, GO:0034220=TAS, GO:0002027=IMP, GO:0010880=ISS, GO:0060315=IDA, GO:0086029=NAS} Purkinje myocyte to ventricular cardiac muscle cell signaling, cellular response to caffeine, detection of calcium ion, ion transmembrane transport, negative regulation of potassium ion transport, negative regulation of ryanodine-sensitive calcium-release channel activity, protein polymerization, regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion, regulation of heart rate, regulation of membrane repolarization, regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum, sequestering of calcium ion, striated muscle contraction, transmembrane transport calcium channel complex, cytoplasm, intracellular, junctional sarcoplasmic reticulum membrane, sarcoplasmic reticulum lumen, sarcoplasmic reticulum membrane, voltage-gated calcium channel complex calcium ion binding, protein binding, protein homodimerization activity Human CASR IntAct UniProtKB {GO:0005515=PMID:20361938, GO:0005513=PMID:7759551, GO:0008284=GO_REF:0000019, GO:0005886=Reactome:REACT_22436, GO:0007635=PMID:7759551, GO:0004930=GO_REF:0000037, GO:0006874=PMID:7874174, GO:0007254=GO_REF:0000019, GO:0032781=GO_REF:0000019, GO:0009653=PMID:7916660, GO:0010628=GO_REF:0000019, GO:0070509=PMID:20846291, GO:0007186=PMID:7759551, GO:0001503=PMID:7874174, GO:0004435=PMID:7874174, GO:0005887=PMID:7759551, GO:0042311=GO_REF:0000019, GO:0051924=GO_REF:0000019, GO:0006816=GO_REF:0000019, GO:0043679=GO_REF:0000019, GO:0016021=GO_REF:0000038} P41180 Extracellular calcium-sensing receptor protein 20130415 {GO:0005515=IPI, GO:0005513=TAS, GO:0008284=IEA, GO:0005886=TAS, GO:0007635=TAS, GO:0004930=IEA, GO:0006874=TAS, GO:0007254=IEA, GO:0032781=IEA, GO:0009653=TAS, GO:0010628=IEA, GO:0070509=IDA, GO:0007186=TAS, GO:0001503=TAS, GO:0004435=TAS, GO:0005887=TAS, GO:0042311=IEA, GO:0051924=IEA, GO:0006816=IEA, GO:0043679=IEA, GO:0016021=IEA} G-protein coupled receptor signaling pathway, JNK cascade, anatomical structure morphogenesis, calcium ion import, calcium ion transport, cellular calcium ion homeostasis, chemosensory behavior, detection of calcium ion, ossification, positive regulation of ATPase activity, positive regulation of cell proliferation, positive regulation of gene expression, regulation of calcium ion transport, vasodilation axon terminus, integral to membrane, integral to plasma membrane, plasma membrane G-protein coupled receptor activity, phosphatidylinositol phospholipase C activity, protein binding Human UniProtKB:Q15363 CASS4 UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0016020=GO_REF:0000002, GO:0005856=GO_REF:0000039, GO:0007155=GO_REF:0000037, GO:0005925=GO_REF:0000039, GO:0000155=GO_REF:0000002} Q9NQ75 Cas scaffolding protein family member 4 protein 20130413 {GO:0005737=IEA, GO:0016020=IEA, GO:0005856=IEA, GO:0007155=IEA, GO:0005925=IEA, GO:0000155=IEA} cell adhesion cytoplasm, cytoskeleton, focal adhesion, membrane phosphorelay sensor kinase activity Human UniProtKB-SubCell:SL-0118 CAST GOC UniProtKB {GO:0010951=PMID:7638179, GO:0005515=PMID:17474147, GO:0004869=GO_REF:0000037, GO:0004866=PMID:7638179, GO:0016020=GO_REF:0000019, GO:0010466=GO_REF:0000019} P20810 Calpastatin protein 20130413 {GO:0010951=TAS, GO:0005515=IPI, GO:0004869=IEA, GO:0004866=TAS, GO:0016020=IEA, GO:0010466=IEA} negative regulation of endopeptidase activity, negative regulation of peptidase activity membrane cysteine-type endopeptidase inhibitor activity, endopeptidase inhibitor activity, protein binding Human CASZ1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q86V15 Zinc finger protein castor homolog 1 protein 20100326 {GO:0005737=IDA, GO:0006355=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0043231=IDA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, intracellular membrane-bounded organelle, nucleolus, nucleus DNA binding, zinc ion binding Human CAT Reactome UniProtKB {GO:0050661=PMID:10656833, GO:0009650=PMID:17053817, GO:0020027=GO_REF:0000019, GO:0005782=Reactome:REACT_615, GO:0005886=GO_REF:0000019, GO:0004096=Reactome:REACT_615, GO:0005783=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0042697=GO_REF:0000019, GO:0005764=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0042803=PMID:10656833, GO:0005829=GO_REF:0000019, GO:0009060=GO_REF:0000019, GO:0005758=GO_REF:0000019, GO:0006195=Reactome:REACT_2086, GO:0051092=GO_REF:0000019, GO:0051289=PMID:21976670, GO:0051781=GO_REF:0000037, GO:0033197=GO_REF:0000019, GO:0004046=GO_REF:0000019, GO:0042744=PMID:18379038, GO:0005778=GO_REF:0000024, GO:0005777=PMID:18379038, GO:0008203=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0043066=PMID:16644728, GO:0005794=GO_REF:0000019, GO:0051262=PMID:11134921, GO:0005102=PMID:21976670, GO:0055086=Reactome:REACT_1698, GO:0014068=GO_REF:0000019, GO:0032088=GO_REF:0000019, GO:0071363=GO_REF:0000019, GO:0006144=Reactome:REACT_522, GO:0055093=GO_REF:0000019, GO:0006641=GO_REF:0000019, GO:0019899=PMID:16781659, GO:0016684=GO_REF:0000024, GO:0000302=PMID:16644728, GO:0020037=PMID:11134921} P04040 Catalase protein 20130213 {GO:0050661=IDA, GO:0009650=IMP, GO:0020027=IEA, GO:0005782=TAS, GO:0005886=IEA, GO:0004096=TAS, GO:0005783=IEA, GO:0044281=TAS, GO:0042697=IEA, GO:0005764=IEA, GO:0046872=IEA, GO:0042803=IDA, GO:0005829=IEA, GO:0009060=IEA, GO:0005758=IEA, GO:0006195=TAS, GO:0051092=IEA, GO:0051289=IDA, GO:0051781=IEA, GO:0033197=IEA, GO:0004046=IEA, GO:0042744=IDA, GO:0005778=ISS, GO:0005777=IDA, GO:0008203=IEA, GO:0001666=IEA, GO:0043066=IMP, GO:0005794=IEA, GO:0051262=IDA, GO:0005102=IPI, GO:0055086=TAS, GO:0014068=IEA, GO:0032088=IEA, GO:0071363=IEA, GO:0006144=TAS, GO:0055093=IEA, GO:0006641=IEA, GO:0019899=IPI, GO:0016684=ISS, GO:0000302=IMP, GO:0020037=IDA} UV protection, aerobic respiration, cellular response to growth factor stimulus, cholesterol metabolic process, hemoglobin metabolic process, hydrogen peroxide catabolic process, menopause, negative regulation of NF-kappaB transcription factor activity, negative regulation of apoptotic process, nucleobase-containing small molecule metabolic process, positive regulation of NF-kappaB transcription factor activity, positive regulation of cell division, positive regulation of phosphatidylinositol 3-kinase cascade, protein homotetramerization, protein tetramerization, purine nucleobase metabolic process, purine nucleotide catabolic process, response to hyperoxia, response to hypoxia, response to reactive oxygen species, response to vitamin E, small molecule metabolic process, triglyceride metabolic process Golgi apparatus, cytosol, endoplasmic reticulum, lysosome, mitochondrial intermembrane space, peroxisomal matrix, peroxisomal membrane, peroxisome, plasma membrane NADP binding, aminoacylase activity, catalase activity, enzyme binding, heme binding, metal ion binding, oxidoreductase activity, acting on peroxide as acceptor, protein homodimerization activity, receptor binding Human CATSPER1 IntAct UniProtKB {GO:0005515=PMID:16740636, GO:0005929=GO_REF:0000037, GO:0005245=GO_REF:0000019, GO:0001539=GO_REF:0000019, GO:0007342=GO_REF:0000019, GO:0036128=GO_REF:0000024, GO:0051924=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0030317=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0030154=GO_REF:0000037} Q8NEC5 Cation channel sperm-associated protein 1 protein 20130415 {GO:0005515=IPI, GO:0005929=IEA, GO:0005245=IEA, GO:0001539=IEA, GO:0007342=IEA, GO:0036128=ISS, GO:0051924=IEA, GO:0007275=IEA, GO:0030317=IEA, GO:0007283=IEA, GO:0030154=IEA} cell differentiation, ciliary or flagellar motility, fusion of sperm to egg plasma membrane, multicellular organismal development, regulation of calcium ion transport, sperm motility, spermatogenesis CatSper complex, cilium protein binding, voltage-gated calcium channel activity Human UniProtKB:Q9P0X4 CATSPER2 IntAct UniProtKB {GO:0005515=PMID:16740636, GO:0005262=GO_REF:0000037, GO:0005244=GO_REF:0000037, GO:0001539=GO_REF:0000019, GO:0036128=GO_REF:0000024, GO:0007275=GO_REF:0000037, GO:0030317=GO_REF:0000019, GO:0007283=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0009566=GO_REF:0000019, GO:0005929=GO_REF:0000037, GO:0016021=GO_REF:0000038, GO:0005216=GO_REF:0000002} Q96P56 Cation channel sperm-associated protein 2 protein 20130415 {GO:0005515=IPI, GO:0005262=IEA, GO:0005244=IEA, GO:0001539=IEA, GO:0036128=ISS, GO:0007275=IEA, GO:0030317=IEA, GO:0007283=IEA, GO:0030154=IEA, GO:0009566=IEA, GO:0005929=IEA, GO:0016021=IEA, GO:0005216=IEA} cell differentiation, ciliary or flagellar motility, fertilization, multicellular organismal development, sperm motility, spermatogenesis CatSper complex, cilium, integral to membrane calcium channel activity, ion channel activity, protein binding, voltage-gated ion channel activity Human UniProtKB:Q9P0X4 CATSPERG UniProtKB UniProtKB {GO:0036128=GO_REF:0000024, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q6ZRH7 Cation channel sperm-associated protein subunit gamma protein 20120329 {GO:0036128=ISS, GO:0007275=IEA, GO:0007283=IEA, GO:0030154=IEA} cell differentiation, multicellular organismal development, spermatogenesis CatSper complex Human UniProtKB:C6KI89 CAV1 BHF-UCL UniProtKB {GO:0005515=PMID:17848177, GO:0043627=PMID:12388746, GO:0019915=GO_REF:0000024, GO:0010524=PMID:19052258, GO:0090263=PMID:16890161, GO:0072584=PMID:19931615, GO:0030879=GO_REF:0000024, GO:0030301=PMID:11294831, GO:0006940=GO_REF:0000024, GO:0050900=Reactome:REACT_12051, GO:2000811=GO_REF:0000019, GO:0052547=GO_REF:0000024, GO:0005113=PMID:11278759, GO:0070836=PMID:12633858, GO:0005622=PMID:15703204, GO:0016050=PMID:12743374, GO:0000165=GO_REF:0000019, GO:0051260=GO_REF:0000024, GO:0031397=GO_REF:0000019, GO:0032507=GO_REF:0000024, GO:0005938=GO_REF:0000019, GO:2000286=PMID:16890161, GO:0005811=Reactome:REACT_12499, GO:0042632=GO_REF:0000024, GO:2001244=PMID:21382479, GO:0000122=GO_REF:0000024, GO:0019217=GO_REF:0000024, GO:0016504=GO_REF:0000024, GO:0043234=GO_REF:0000019, GO:0051592=PMID:19052258, GO:0048554=GO_REF:0000024, GO:0051001=GO_REF:0000019, GO:0007519=GO_REF:0000024, GO:0005887=GO_REF:0000019, GO:0002931=GO_REF:0000019, GO:0032570=PMID:12388746, GO:0006641=GO_REF:0000024, GO:0045121=PMID:17010968, GO:0019899=PMID:20122998, GO:0050998=PMID:12852865, GO:0032091=PMID:16890161, GO:2001238=PMID:21382479, GO:0048471=GO_REF:0000024, GO:0051899=GO_REF:0000024, GO:0005886=PMID:11278759, GO:0005783=PMID:11294831, GO:0050999=Reactome:REACT_12541, GO:0031295=PMID:17287217, GO:0042524=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0055074=GO_REF:0000024, GO:0044432=PMID:22792322, GO:0000188=GO_REF:0000024, GO:0043409=GO_REF:0000024, GO:0033138=PMID:18081315, GO:0008104=GO_REF:0000024, GO:0001960=GO_REF:0000019, GO:0045907=GO_REF:0000024, GO:0033137=PMID:18081315, GO:0045019=GO_REF:0000024, GO:0033484=GO_REF:0000024, GO:0030857=GO_REF:0000024, GO:0015485=PMID:11294831, GO:0042310=GO_REF:0000019, GO:0046209=Reactome:REACT_12508, GO:0006816=GO_REF:0000024, GO:0002080=GO_REF:0000019, GO:0090090=GO_REF:0000024, GO:0001666=GO_REF:0000024, GO:0051480=PMID:19052258, GO:0060056=GO_REF:0000024, GO:0005102=PMID:16890161, GO:0071455=PMID:21382479, GO:0006874=GO_REF:0000024, GO:0001525=GO_REF:0000019, GO:0097190=PMID:21382479, GO:0046426=GO_REF:0000024, GO:0030666=Reactome:REACT_12634, GO:0032947=PMID:19052258, GO:0030193=PMID:17848177, GO:0007595=GO_REF:0000019, GO:0000139=Reactome:REACT_12637, GO:0007596=Reactome:REACT_604, GO:0001937=GO_REF:0000024, GO:0005198=PMID:11865038, GO:0005901=PMID:18081315, GO:0019048=GO_REF:0000037, GO:0003057=GO_REF:0000019, GO:0001570=GO_REF:0000024, GO:0005768=PMID:20682791} Q03135 Caveolin-1 protein 20080215 {GO:0005515=IPI, GO:0043627=IDA, GO:0019915=ISS, GO:0010524=ISS, GO:0090263=IMP, GO:0072584=IDA, GO:0030879=ISS, GO:0030301=TAS, GO:0006940=ISS, GO:0050900=TAS, GO:2000811=IEA, GO:0052547=ISS, GO:0005113=IPI, GO:0070836=IMP, GO:0005622=IDA, GO:0016050=IDA, GO:0000165=IEA, GO:0051260=ISS, GO:0031397=IEA, GO:0032507=ISS, GO:0005938=IEA, GO:2000286=IMP, GO:0005811=TAS, GO:0042632=ISS, GO:2001244=IMP, GO:0000122=ISS, GO:0019217=ISS, GO:0016504=ISS, GO:0043234=IEA, GO:0051592=ISS, GO:0048554=ISS, GO:0051001=IEA, GO:0007519=ISS, GO:0005887=IEA, GO:0002931=IEA, GO:0032570=IDA, GO:0006641=ISS, GO:0045121=IDA, GO:0019899=IPI, GO:0050998=IPI, GO:0032091=IDA, GO:2001238=IMP, GO:0048471=ISS, GO:0051899=ISS, GO:0005886=IDA, GO:0005783=IDA, GO:0050999=TAS, GO:0031295=IDA, GO:0042524=IEA, GO:0044281=TAS, GO:0055074=ISS, GO:0044432=IDA, GO:0000188=ISS, GO:0043409=ISS, GO:0033138=IDA, GO:0008104=ISS, GO:0001960=IEA, GO:0045907=ISS, GO:0033137=IDA, GO:0045019=ISS, GO:0033484=ISS, GO:0030857=ISS, GO:0015485=TAS, GO:0042310=IEA, GO:0046209=TAS, GO:0006816=ISS, GO:0002080=IEA, GO:0090090=ISS, GO:0001666=ISS, GO:0051480=IDA, GO:0060056=ISS, GO:0005102=IPI, GO:0071455=IMP, GO:0006874=ISS, GO:0001525=IEA, GO:0097190=IMP, GO:0046426=ISS, GO:0030666=TAS, GO:0032947=TAS, GO:0030193=IMP, GO:0007595=IEA, GO:0000139=TAS, GO:0007596=TAS, GO:0001937=ISS, GO:0005198=IDA, GO:0005901=IDA, GO:0019048=IEA, GO:0003057=IEA, GO:0001570=ISS, GO:0005768=IDA} MAPK cascade, T cell costimulation, angiogenesis, apoptotic signaling pathway, blood coagulation, calcium ion homeostasis, calcium ion transport, caveola assembly, caveolin-mediated endocytosis, cellular calcium ion homeostasis, cellular response to hyperoxia, cholesterol homeostasis, cholesterol transport, cytosolic calcium ion homeostasis, inactivation of MAPK activity, lactation, leukocyte migration, lipid storage, maintenance of protein location in cell, mammary gland development, mammary gland involution, membrane depolarization, negative regulation of JAK-STAT cascade, negative regulation of MAPK cascade, negative regulation of anoikis, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cytokine-mediated signaling pathway, negative regulation of endothelial cell proliferation, negative regulation of epithelial cell differentiation, negative regulation of nitric oxide biosynthetic process, negative regulation of nitric-oxide synthase activity, negative regulation of peptidyl-serine phosphorylation, negative regulation of protein binding, negative regulation of protein ubiquitination, negative regulation of transcription from RNA polymerase II promoter, negative regulation of tyrosine phosphorylation of Stat5 protein, nitric oxide homeostasis, nitric oxide metabolic process, positive regulation of calcium ion transport into cytosol, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of extrinsic apoptotic signaling pathway, positive regulation of intrinsic apoptotic signaling pathway, positive regulation of metalloenzyme activity, positive regulation of peptidyl-serine phosphorylation, positive regulation of vasoconstriction, protein homooligomerization, protein localization, receptor internalization involved in canonical Wnt receptor signaling pathway, regulation of blood coagulation, regulation of fatty acid metabolic process, regulation of nitric-oxide synthase activity, regulation of peptidase activity, regulation of smooth muscle contraction, regulation of the force of heart contraction by chemical signal, response to calcium ion, response to estrogen stimulus, response to hypoxia, response to ischemia, response to progesterone stimulus, skeletal muscle tissue development, small molecule metabolic process, triglyceride metabolic process, vasculogenesis, vasoconstriction, vesicle organization, virus-host interaction Golgi membrane, acrosomal membrane, caveola, cell cortex, endocytic vesicle membrane, endoplasmic reticulum, endoplasmic reticulum part, endosome, integral to plasma membrane, intracellular, lipid particle, membrane raft, perinuclear region of cytoplasm, plasma membrane, protein complex cholesterol binding, enzyme binding, nitric-oxide synthase binding, patched binding, peptidase activator activity, protein binding, protein complex scaffold, receptor binding, structural molecule activity Human CAV2 BHF-UCL UniProtKB {GO:0051219=GO_REF:0000019, GO:0005515=PMID:15703204, GO:0030133=GO_REF:0000054, GO:0048471=PMID:18081315, GO:0005886=PMID:15569306, GO:0007268=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0006906=PMID:12743374, GO:0051259=GO_REF:0000019, GO:0042803=PMID:8552590, GO:0070836=PMID:12633858, GO:0005829=GO_REF:0000019, GO:0005622=PMID:15703204, GO:0044432=PMID:22792322, GO:0016050=PMID:12743374, GO:0060161=PMID:15569306, GO:0002080=GO_REF:0000019, GO:0048278=PMID:12743374, GO:0030512=GO_REF:0000019, GO:0019905=GO_REF:0000019, GO:0005811=GO_REF:0000019, GO:0007088=PMID:18081315, GO:0005794=GO_REF:0000024, GO:0009986=GO_REF:0000019, GO:0048741=GO_REF:0000024, GO:0031234=PMID:15569306, GO:0043234=GO_REF:0000019, GO:0001938=GO_REF:0000019, GO:0000139=GO_REF:0000039, GO:0001937=GO_REF:0000024, GO:0005887=PMID:8552590, GO:0005901=PMID:18081315, GO:0045121=PMID:11294831, GO:0007005=GO_REF:0000024, GO:0007029=GO_REF:0000024} P51636 Caveolin-2 protein 20090827 {GO:0051219=IEA, GO:0005515=IPI, GO:0030133=IDA, GO:0048471=IDA, GO:0005886=IDA, GO:0007268=IEA, GO:0005634=IEA, GO:0006906=IDA, GO:0051259=IEA, GO:0042803=IDA, GO:0070836=IMP, GO:0005829=IEA, GO:0005622=IDA, GO:0044432=IDA, GO:0016050=IDA, GO:0060161=IMP, GO:0002080=IEA, GO:0048278=IDA, GO:0030512=IEA, GO:0019905=IEA, GO:0005811=IEA, GO:0007088=IEP, GO:0005794=ISS, GO:0009986=IEA, GO:0048741=ISS, GO:0031234=IDA, GO:0043234=IEA, GO:0001938=IEA, GO:0000139=IEA, GO:0001937=ISS, GO:0005887=IDA, GO:0005901=IDA, GO:0045121=IDA, GO:0007005=ISS, GO:0007029=ISS} caveola assembly, endoplasmic reticulum organization, mitochondrion organization, negative regulation of endothelial cell proliferation, negative regulation of transforming growth factor beta receptor signaling pathway, positive regulation of dopamine receptor signaling pathway, positive regulation of endothelial cell proliferation, protein oligomerization, regulation of mitosis, skeletal muscle fiber development, synaptic transmission, vesicle docking, vesicle fusion, vesicle organization Golgi apparatus, Golgi membrane, acrosomal membrane, caveola, cell surface, cytosol, endoplasmic reticulum part, extrinsic to internal side of plasma membrane, integral to plasma membrane, intracellular, lipid particle, membrane raft, nucleus, perinuclear region of cytoplasm, plasma membrane, protein complex, transport vesicle phosphoprotein binding, protein binding, protein homodimerization activity, syntaxin binding Human CAV3 BHF-UCL UniProtKB {GO:0005515=PMID:10988290, GO:0030018=GO_REF:0000024, GO:0031594=GO_REF:0000024, GO:0008016=GO_REF:0000024, GO:0010831=GO_REF:0000019, GO:0051394=PMID:20472890, GO:0031122=GO_REF:0000019, GO:0060307=PMID:17060380, GO:0032403=PMID:10988290, GO:1900825=PMID:17275750, GO:0030154=GO_REF:0000024, GO:0070836=PMID:18936328, GO:0060373=PMID:17060380, GO:0016010=PMID:10988290, GO:1900744=GO_REF:0000019, GO:0051926=PMID:21084288, GO:0017015=GO_REF:0000019, GO:0071253=PMID:19544087, GO:0051647=GO_REF:0000019, GO:0042632=GO_REF:0000024, GO:0009986=GO_REF:0000019, GO:0060762=GO_REF:0000019, GO:0007520=GO_REF:0000019, GO:0033292=PMID:12847114, GO:0044325=PMID:21084288, GO:0060347=GO_REF:0000019, GO:0045792=PMID:12847114, GO:0007517=PMID:10988290, GO:0061052=GO_REF:0000019, GO:0051001=GO_REF:0000024, GO:0002027=PMID:17060380, GO:0055117=PMID:17275750, GO:0006641=GO_REF:0000024, GO:0016049=GO_REF:0000024, GO:0055013=GO_REF:0000019, GO:0050998=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0005886=PMID:20472890, GO:0005783=PMID:22792322, GO:0014819=PMID:17524427, GO:0007204=GO_REF:0000024, GO:0051896=GO_REF:0000019, GO:0010614=PMID:12847114, GO:0038009=PMID:20472890, GO:0043407=PMID:12847114, GO:0042391=PMID:21084288, GO:0001778=GO_REF:0000019, GO:0007015=GO_REF:0000019, GO:0031116=GO_REF:0000024, GO:0090279=PMID:21084288, GO:0043014=GO_REF:0000019, GO:0030315=GO_REF:0000024, GO:0042593=GO_REF:0000024, GO:2000649=PMID:17275750, GO:0008022=PMID:10988290, GO:0031982=GO_REF:0000019, GO:0042383=PMID:17060380, GO:0032947=PMID:17060380, GO:0000139=GO_REF:0000039, GO:0060299=PMID:12847114, GO:0005901=GO_REF:0000039, GO:0090002=GO_REF:0000019, GO:0017080=PMID:17275750} P56539 Caveolin-3 protein 20120801 {GO:0005515=IPI, GO:0030018=ISS, GO:0031594=ISS, GO:0008016=ISS, GO:0010831=IEA, GO:0051394=IMP, GO:0031122=IEA, GO:0060307=IMP, GO:0032403=IDA, GO:1900825=IMP, GO:0030154=ISS, GO:0070836=IDA, GO:0060373=IDA, GO:0016010=IDA, GO:1900744=IEA, GO:0051926=IDA, GO:0017015=IEA, GO:0071253=IDA, GO:0051647=IEA, GO:0042632=ISS, GO:0009986=IEA, GO:0060762=IEA, GO:0007520=IEA, GO:0033292=TAS, GO:0044325=IPI, GO:0060347=IEA, GO:0045792=IMP, GO:0007517=TAS, GO:0061052=IEA, GO:0051001=ISS, GO:0002027=IMP, GO:0055117=IMP, GO:0006641=ISS, GO:0016049=ISS, GO:0055013=IEA, GO:0050998=IEA, GO:0008284=IEA, GO:0005886=IDA, GO:0005783=IDA, GO:0014819=IMP, GO:0007204=ISS, GO:0051896=IEA, GO:0010614=IMP, GO:0038009=IMP, GO:0043407=IMP, GO:0042391=IDA, GO:0001778=IEA, GO:0007015=IEA, GO:0031116=ISS, GO:0090279=IDA, GO:0043014=IEA, GO:0030315=ISS, GO:0042593=ISS, GO:2000649=IDA, GO:0008022=IDA, GO:0031982=IEA, GO:0042383=IDA, GO:0032947=IPI, GO:0000139=IEA, GO:0060299=IMP, GO:0005901=IEA, GO:0090002=IEA, GO:0017080=IMP} T-tubule organization, actin filament organization, cardiac muscle cell development, caveola assembly, cell differentiation, cell growth, cholesterol homeostasis, cytoplasmic microtubule organization, elevation of cytosolic calcium ion concentration, establishment of protein localization to plasma membrane, glucose homeostasis, heart trabecula formation, muscle organ development, myoblast fusion, negative regulation of MAP kinase activity, negative regulation of calcium ion transport, negative regulation of cardiac muscle hypertrophy, negative regulation of cell growth involved in cardiac muscle cell development, negative regulation of cell size, negative regulation of nitric-oxide synthase activity, negative regulation of sarcomere organization, nucleus localization, plasma membrane repair, positive regulation of cell proliferation, positive regulation of microtubule polymerization, positive regulation of myotube differentiation, regulation of branching involved in mammary gland duct morphogenesis, regulation of calcium ion import, regulation of cardiac muscle contraction, regulation of heart contraction, regulation of heart rate, regulation of membrane depolarization involved in regulation of cardiac muscle cell action potential, regulation of membrane potential, regulation of nerve growth factor receptor activity, regulation of p38MAPK cascade, regulation of protein kinase B signaling cascade, regulation of signal transduction by receptor internalization, regulation of skeletal muscle contraction, regulation of sodium ion transmembrane transporter activity, regulation of transforming growth factor beta receptor signaling pathway, regulation of ventricular cardiac muscle cell membrane depolarization, regulation of ventricular cardiac muscle cell membrane repolarization, triglyceride metabolic process Golgi membrane, T-tubule, Z disc, caveola, cell surface, dystrophin-associated glycoprotein complex, endoplasmic reticulum, neuromuscular junction, plasma membrane, sarcolemma, vesicle alpha-tubulin binding, connexin binding, ion channel binding, nitric-oxide synthase binding, protein C-terminus binding, protein binding, protein complex binding, protein complex scaffold, sodium channel regulator activity Human UniProtKB:P51637 CBFA2T2 InterPro UniProtKB {GO:0005515=PMID:19060904, GO:0003700=GO_REF:0000002, GO:0045944=GO_REF:0000019, GO:0003714=PMID:19026687, GO:0010976=PMID:19026687, GO:0030855=GO_REF:0000019, GO:0010977=GO_REF:0000024, GO:0005634=PMID:19026687, GO:0008270=GO_REF:0000002, GO:0045892=GO_REF:0000019} Q5TGE8 Protein CBFA2T2 protein 20130413 {GO:0005515=IPI, GO:0003700=IEA, GO:0045944=IEA, GO:0003714=IDA, GO:0010976=IDA, GO:0030855=IEA, GO:0010977=ISS, GO:0005634=IDA, GO:0008270=IEA, GO:0045892=IEA} epithelial cell differentiation, negative regulation of neuron projection development, negative regulation of transcription, DNA-dependent, positive regulation of neuron projection development, positive regulation of transcription from RNA polymerase II promoter nucleus protein binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity, zinc ion binding Human InterPro:IPR003894 CBFA2T3 IntAct UniProtKB {GO:0005515=PMID:16966434, GO:0005622=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0000139=GO_REF:0000039, GO:0008283=PMID:9447981, GO:0045944=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0005730=GO_REF:0000039, GO:0005654=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0030851=PMID:15231665, GO:0006351=GO_REF:0000037} O75081 Protein CBFA2T3 protein 20130415 {GO:0005515=IPI, GO:0005622=IEA, GO:0003700=IEA, GO:0000139=IEA, GO:0008283=TAS, GO:0045944=IEA, GO:0003682=IEA, GO:0005730=IEA, GO:0005654=IEA, GO:0008270=IEA, GO:0030851=IDA, GO:0006351=IEA} cell proliferation, granulocyte differentiation, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent Golgi membrane, intracellular, nucleolus, nucleoplasm chromatin binding, protein binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB:Q9Y2D9 CBFB IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0003700=PMID:9751756, GO:0006366=PMID:8351518, GO:0003713=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0060216=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0003677=GO_REF:0000019, GO:0001649=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0030098=GO_REF:0000019, GO:0030099=GO_REF:0000019, GO:0048469=GO_REF:0000019} Q13951 Core-binding factor subunit beta protein 20130415 {GO:0005515=IPI, GO:0003700=TAS, GO:0006366=TAS, GO:0003713=IEA, GO:0005634=IEA, GO:0060216=IEA, GO:0005575=ND, GO:0003677=IEA, GO:0001649=IEA, GO:0045944=IEA, GO:0030098=IEA, GO:0030099=IEA, GO:0048469=IEA} cell maturation, definitive hemopoiesis, lymphocyte differentiation, myeloid cell differentiation, osteoblast differentiation, positive regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter cellular_component, nucleus DNA binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity Human UniProtKB:P12504 CBL GOC UniProtKB {GO:0005515=PMID:10068674, GO:0006355=PMID:2030914, GO:0017124=PMID:9447983, GO:0043066=PMID:18070883, GO:0004842=Reactome:REACT_111141, GO:0003700=PMID:2030914, GO:0016567=PMID:15465819, GO:0005886=Reactome:REACT_118834, GO:0005509=GO_REF:0000002, GO:0042059=Reactome:REACT_12484, GO:0014068=PMID:17003487, GO:0005634=GO_REF:0000002, GO:0016600=GO_REF:0000024, GO:0005829=Reactome:REACT_118834, GO:0005737=GO_REF:0000052, GO:0007173=Reactome:REACT_9417, GO:0046875=PMID:18034775, GO:0008543=Reactome:REACT_9470, GO:0048260=PMID:15465819, GO:0001784=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0004871=GO_REF:0000002, GO:0007166=PMID:15465819} P22681 E3 ubiquitin-protein ligase CBL protein 20130413 {GO:0005515=IPI, GO:0006355=TAS, GO:0017124=IPI, GO:0043066=IMP, GO:0004842=TAS, GO:0003700=TAS, GO:0016567=TAS, GO:0005886=TAS, GO:0005509=IEA, GO:0042059=TAS, GO:0014068=IMP, GO:0005634=IEA, GO:0016600=ISS, GO:0005829=TAS, GO:0005737=IDA, GO:0007173=TAS, GO:0046875=IPI, GO:0008543=TAS, GO:0048260=TAS, GO:0001784=IEA, GO:0008270=IEA, GO:0004871=IEA, GO:0007166=TAS} cell surface receptor signaling pathway, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, negative regulation of apoptotic process, negative regulation of epidermal growth factor receptor signaling pathway, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of receptor-mediated endocytosis, protein ubiquitination, regulation of transcription, DNA-dependent cytoplasm, cytosol, flotillin complex, nucleus, plasma membrane SH3 domain binding, calcium ion binding, ephrin receptor binding, phosphotyrosine binding, protein binding, sequence-specific DNA binding transcription factor activity, signal transducer activity, ubiquitin-protein ligase activity, zinc ion binding Human CBLB HPA UniProtKB {GO:0005515=PMID:21706016, GO:0004842=GO_REF:0000002, GO:0045732=GO_REF:0000019, GO:0005886=Reactome:REACT_118834, GO:0023051=GO_REF:0000002, GO:0046642=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006607=PMID:7784085, GO:0050860=GO_REF:0000019, GO:0005829=Reactome:REACT_118834, GO:0035556=GO_REF:0000019, GO:0007165=PMID:7784085, GO:0006955=GO_REF:0000019, GO:0042110=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0002669=GO_REF:0000019, GO:0001784=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0004871=GO_REF:0000002, GO:0007166=GO_REF:0000002} Q13191 E3 ubiquitin-protein ligase CBL-B protein 20100326 {GO:0005515=IPI, GO:0004842=IEA, GO:0045732=IEA, GO:0005886=TAS, GO:0023051=IEA, GO:0046642=IEA, GO:0005509=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006607=TAS, GO:0050860=IEA, GO:0005829=TAS, GO:0035556=IEA, GO:0007165=TAS, GO:0006955=IEA, GO:0042110=IEA, GO:0005737=IDA, GO:0002669=IEA, GO:0001784=IEA, GO:0008270=IEA, GO:0004871=IEA, GO:0007166=IEA} NLS-bearing substrate import into nucleus, T cell activation, cell surface receptor signaling pathway, immune response, intracellular signal transduction, negative regulation of T cell receptor signaling pathway, negative regulation of alpha-beta T cell proliferation, positive regulation of T cell anergy, positive regulation of protein catabolic process, regulation of signaling, signal transduction cytoplasm, cytosol, nucleolus, nucleus, plasma membrane calcium ion binding, phosphotyrosine binding, protein binding, signal transducer activity, ubiquitin-protein ligase activity, zinc ion binding Human CBLC BHF-UCL UniProtKB {GO:0004842=PMID:14661060, GO:0017124=PMID:10362357, GO:0005154=PMID:10362357, GO:0005509=GO_REF:0000002, GO:0042059=PMID:10362357, GO:0005634=GO_REF:0000039, GO:0042787=PMID:14661060, GO:0043407=PMID:10362357, GO:0007175=PMID:10362357, GO:0008270=GO_REF:0000002, GO:0001784=PMID:14661060, GO:0004871=GO_REF:0000002, GO:0007166=GO_REF:0000002} Q9ULV8 Signal transduction protein CBL-C protein 20090408 {GO:0004842=IDA, GO:0017124=IDA, GO:0005154=IDA, GO:0005509=IEA, GO:0042059=IDA, GO:0005634=IEA, GO:0042787=IDA, GO:0043407=IDA, GO:0007175=IDA, GO:0008270=IEA, GO:0001784=IDA, GO:0004871=IEA, GO:0007166=IEA} cell surface receptor signaling pathway, negative regulation of MAP kinase activity, negative regulation of epidermal growth factor receptor signaling pathway, negative regulation of epidermal growth factor-activated receptor activity, protein ubiquitination involved in ubiquitin-dependent protein catabolic process nucleus SH3 domain binding, calcium ion binding, epidermal growth factor receptor binding, phosphotyrosine binding, signal transducer activity, ubiquitin-protein ligase activity, zinc ion binding Human CBLL1 UniProtKB UniProtKB {GO:0005515=PMID:11836526, GO:0045807=GO_REF:0000024, GO:0016337=PMID:11836526, GO:0007162=GO_REF:0000024, GO:0004842=GO_REF:0000024, GO:0016567=PMID:14996930, GO:0030335=GO_REF:0000024, GO:0000151=PMID:14996930, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q75N03 E3 ubiquitin-protein ligase Hakai protein 20090803 {GO:0005515=IPI, GO:0045807=ISS, GO:0016337=IDA, GO:0007162=ISS, GO:0004842=ISS, GO:0016567=TAS, GO:0030335=ISS, GO:0000151=IC, GO:0008270=IEA, GO:0003676=IEA} cell-cell adhesion, negative regulation of cell adhesion, positive regulation of cell migration, positive regulation of endocytosis, protein ubiquitination ubiquitin ligase complex nucleic acid binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q9JIY2 CBLN1 PINC UniProtKB {GO:0051965=GO_REF:0000019, GO:0009306=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000037, GO:0045211=GO_REF:0000039, GO:0007268=PMID:1704129, GO:0005576=GO_REF:0000039, GO:0042803=GO_REF:0000019, GO:0007399=PMID:1704129} P23435 Cerebellin-1 protein 20030904 {GO:0051965=IEA, GO:0009306=IEA, GO:0030054=IEA, GO:0005886=IEA, GO:0045211=IEA, GO:0007268=TAS, GO:0005576=IEA, GO:0042803=IEA, GO:0007399=TAS} nervous system development, positive regulation of synapse assembly, protein secretion, synaptic transmission cell junction, extracellular region, plasma membrane, postsynaptic membrane protein homodimerization activity Human CBLN2 ENSEMBL UniProtKB {GO:0051965=GO_REF:0000019, GO:0005615=GO_REF:0000019} Q8IUK8 Cerebellin-2 protein 20130413 {GO:0051965=IEA, GO:0005615=IEA} positive regulation of synapse assembly extracellular space Human Ensembl:ENSMUSP00000113695 CBLN3 UniProtKB UniProtKB {GO:0005794=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0005783=GO_REF:0000039, GO:0045202=GO_REF:0000039, GO:0005615=GO_REF:0000019} Q6UW01 Cerebellin-3 protein 20130413 {GO:0005794=IEA, GO:0030054=IEA, GO:0005783=IEA, GO:0045202=IEA, GO:0005615=IEA} Golgi apparatus, cell junction, endoplasmic reticulum, extracellular space, synapse Human UniProtKB-SubCell:SL-0258 CBLN4 UniProtKB UniProtKB {GO:0009306=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0045202=GO_REF:0000039, GO:0005615=GO_REF:0000019} Q9NTU7 Cerebellin-4 protein 20130413 {GO:0009306=IEA, GO:0030054=IEA, GO:0045202=IEA, GO:0005615=IEA} protein secretion cell junction, extracellular space, synapse Human UniProtKB-SubCell:SL-0258 CBR1 Reactome UniProtKB {GO:0019371=Reactome:REACT_150149, GO:0019369=Reactome:REACT_147851, GO:0047021=GO_REF:0000003, GO:0004090=PMID:18449627, GO:0017144=PMID:18449627, GO:0050221=GO_REF:0000003, GO:0016491=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0042373=PMID:18449627, GO:0005829=Reactome:REACT_150185, GO:0055114=PMID:19442656} P16152 "Carbonyl reductase ""NADPH"" 1" protein 20130301 {GO:0019371=TAS, GO:0019369=TAS, GO:0047021=IEA, GO:0004090=IDA, GO:0017144=IDA, GO:0050221=IEA, GO:0016491=IEA, GO:0044281=TAS, GO:0042373=IDA, GO:0005829=TAS, GO:0055114=IDA} arachidonic acid metabolic process, cyclooxygenase pathway, drug metabolic process, oxidation-reduction process, small molecule metabolic process, vitamin K metabolic process cytosol 15-hydroxyprostaglandin dehydrogenase (NADP+) activity, carbonyl reductase (NADPH) activity, oxidoreductase activity, prostaglandin-E2 9-reductase activity Human CBR3 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0004090=PMID:18493841, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0070402=PMID:18493841, GO:0042376=GO_REF:0000019, GO:0005829=PMID:18493841, GO:0000253=GO_REF:0000019} O75828 "Carbonyl reductase ""NADPH"" 3" protein 20090616 {GO:0005737=IDA, GO:0004090=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0070402=IDA, GO:0042376=IEA, GO:0005829=IDA, GO:0000253=IEA} phylloquinone catabolic process cytoplasm, cytosol, nucleolus, nucleus 3-keto sterol reductase activity, NADPH binding, carbonyl reductase (NADPH) activity Human CBR4 UniProtKB UniProtKB {GO:0044598=PMID:20837989, GO:0005515=PMID:19571038, GO:0044597=PMID:20837989, GO:0048038=GO_REF:0000024, GO:0051289=PMID:19000905, GO:0005759=GO_REF:0000024, GO:0003955=PMID:20837989, GO:0016491=GO_REF:0000002, GO:0006633=GO_REF:0000041, GO:0070402=GO_REF:0000024, GO:0008753=GO_REF:0000024} Q8N4T8 Carbonyl reductase family member 4 protein 20090828 {GO:0044598=IMP, GO:0005515=IPI, GO:0044597=IMP, GO:0048038=ISS, GO:0051289=IPI, GO:0005759=ISS, GO:0003955=IDA, GO:0016491=IEA, GO:0006633=IEA, GO:0070402=ISS, GO:0008753=ISS} daunorubicin metabolic process, doxorubicin metabolic process, fatty acid biosynthetic process, protein homotetramerization mitochondrial matrix NAD(P)H dehydrogenase (quinone) activity, NADPH binding, NADPH dehydrogenase (quinone) activity, oxidoreductase activity, protein binding, quinone binding Human UniProtKB:Q8N4T8 CBS HPA UniProtKB {GO:0005515=PMID:17087506, GO:0019343=GO_REF:0000002, GO:0070814=GO_REF:0000024, GO:0019346=Reactome:REACT_115589, GO:0006801=GO_REF:0000019, GO:0006535=GO_REF:0000002, GO:0005634=PMID:17087506, GO:0044281=Reactome:REACT_111217, GO:0042803=PMID:11483494, GO:0050667=PMID:20031578, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_115874, GO:0043231=GO_REF:0000052, GO:0072341=PMID:20031578, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000002, GO:0050880=GO_REF:0000019, GO:0060351=GO_REF:0000019, GO:0043506=GO_REF:0000019, GO:0004124=GO_REF:0000003, GO:0004122=Reactome:REACT_115874, GO:0031625=PMID:17087506, GO:0043066=GO_REF:0000019, GO:0060135=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0021587=GO_REF:0000019, GO:0071456=GO_REF:0000019, GO:0051593=GO_REF:0000019, GO:0001958=GO_REF:0000019, GO:0000096=Reactome:REACT_115639, GO:0043418=PMID:18776696, GO:0001974=GO_REF:0000019, GO:0030170=PMID:7929220, GO:0006563=PMID:19010420, GO:0019899=PMID:17087506, GO:0019448=PMID:15520012, GO:0006565=PMID:18776696, GO:0016740=GO_REF:0000038, GO:0020037=PMID:7929220, GO:0030823=GO_REF:0000019} P35520 Cystathionine beta-synthase protein 20080818 {GO:0005515=IPI, GO:0019343=IEA, GO:0070814=ISS, GO:0019346=TAS, GO:0006801=IEA, GO:0006535=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0042803=IDA, GO:0050667=IDA, GO:0046872=IEA, GO:0005829=TAS, GO:0043231=IDA, GO:0072341=IDA, GO:0034641=TAS, GO:0005737=IEA, GO:0050880=IEA, GO:0060351=IEA, GO:0043506=IEA, GO:0004124=IEA, GO:0004122=TAS, GO:0031625=IPI, GO:0043066=IEA, GO:0060135=IEA, GO:0005730=IDA, GO:0021587=IEA, GO:0071456=IEA, GO:0051593=IEA, GO:0001958=IEA, GO:0000096=TAS, GO:0043418=IDA, GO:0001974=IEA, GO:0030170=IDA, GO:0006563=IDA, GO:0019899=IPI, GO:0019448=IDA, GO:0006565=IDA, GO:0016740=IEA, GO:0020037=IDA, GO:0030823=IEA} L-cysteine catabolic process, L-serine catabolic process, L-serine metabolic process, blood vessel remodeling, cartilage development involved in endochondral bone morphogenesis, cellular nitrogen compound metabolic process, cellular response to hypoxia, cerebellum morphogenesis, cysteine biosynthetic process from serine, cysteine biosynthetic process via cystathionine, endochondral ossification, homocysteine catabolic process, homocysteine metabolic process, hydrogen sulfide biosynthetic process, maternal process involved in female pregnancy, negative regulation of apoptotic process, regulation of JUN kinase activity, regulation of blood vessel size, regulation of cGMP metabolic process, response to folic acid, small molecule metabolic process, sulfur amino acid metabolic process, superoxide metabolic process, transsulfuration cytoplasm, cytosol, intracellular membrane-bounded organelle, nucleolus, nucleus cystathionine beta-synthase activity, cysteine synthase activity, enzyme binding, heme binding, metal ion binding, modified amino acid binding, protein binding, protein homodimerization activity, pyridoxal phosphate binding, transferase activity, ubiquitin protein ligase binding Human CBWD1 UniProtKB UniProtKB {GO:0005524=GO_REF:0000037} Q9BRT8 COBW domain-containing protein 1 protein 20130413 {GO:0005524=IEA} ATP binding Human UniProtKB-KW:KW-0067 CBWD2 UniProtKB UniProtKB {GO:0005524=GO_REF:0000037} Q8IUF1 COBW domain-containing protein 2 protein 20130413 {GO:0005524=IEA} ATP binding Human UniProtKB-KW:KW-0067 CBWD3 UniProtKB UniProtKB {GO:0005524=GO_REF:0000037} Q5JTY5 COBW domain-containing protein 3 protein 20130413 {GO:0005524=IEA} ATP binding Human UniProtKB-KW:KW-0067 CBWD5 UniProtKB UniProtKB {GO:0005524=GO_REF:0000037} Q5RIA9 COBW domain-containing protein 5 protein 20130413 {GO:0005524=IEA} ATP binding Human UniProtKB-KW:KW-0067 CBWD6 UniProtKB UniProtKB {GO:0005524=GO_REF:0000037} Q4V339 COBW domain-containing protein 6 protein 20130413 {GO:0005524=IEA} ATP binding Human UniProtKB-KW:KW-0067 CBWD7 UniProtKB UniProtKB {GO:0005524=GO_REF:0000037} A6NM15 Putative COBW domain-containing protein 7 protein 20130413 {GO:0005524=IEA} ATP binding Human UniProtKB-KW:KW-0067 CBX1 BHF-UCL UniProtKB {GO:0005515=PMID:9636146, GO:0010369=GO_REF:0000019, GO:0005819=PMID:11101528, GO:0005634=GO_REF:0000038, GO:0042802=GO_REF:0000019, GO:0005720=PMID:9169582, GO:0001939=GO_REF:0000019, GO:0005721=GO_REF:0000019, GO:0003682=PMID:9169582, GO:0005654=PMID:9169582, GO:0001940=GO_REF:0000019, GO:0019899=PMID:19486527, GO:0045892=GO_REF:0000019, GO:0000785=PMID:11101528, GO:0000775=PMID:8287692} P83916 Chromobox protein homolog 1 protein 20081022 {GO:0005515=IPI, GO:0010369=IEA, GO:0005819=IDA, GO:0005634=IEA, GO:0042802=IEA, GO:0005720=TAS, GO:0001939=IEA, GO:0005721=IEA, GO:0003682=TAS, GO:0005654=TAS, GO:0001940=IEA, GO:0019899=IPI, GO:0045892=IEA, GO:0000785=IDA, GO:0000775=IDA} negative regulation of transcription, DNA-dependent centromeric heterochromatin, chromatin, chromocenter, chromosome, centromeric region, female pronucleus, male pronucleus, nuclear heterochromatin, nucleoplasm, nucleus, spindle chromatin binding, enzyme binding, identical protein binding, protein binding Human UniProtKB:P23497-2 CBX2 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0000792=GO_REF:0000019, GO:0035102=PMID:19636380, GO:0031519=PMID:21282530, GO:0045137=PMID:19361780, GO:0005634=PMID:21282530, GO:0035064=GO_REF:0000019, GO:0000122=PMID:21282530, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0003682=GO_REF:0000019, GO:0045892=GO_REF:0000029, GO:0016568=GO_REF:0000029} Q14781 Chromobox protein homolog 2 protein 20130415 {GO:0005515=IPI, GO:0000792=IEA, GO:0035102=IDA, GO:0031519=IDA, GO:0045137=IMP, GO:0005634=IDA, GO:0035064=IEA, GO:0000122=IMP, GO:0003677=IEA, GO:0006351=IEA, GO:0030154=IEA, GO:0003682=IEA, GO:0045892=NAS, GO:0016568=NAS} cell differentiation, chromatin modification, development of primary sexual characteristics, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, transcription, DNA-dependent PRC1 complex, PcG protein complex, heterochromatin, nucleus DNA binding, chromatin binding, methylated histone residue binding, protein binding Human UniProtKB:Q99750 CBX3 BHF-UCL UniProtKB {GO:0005515=PMID:9636147, GO:0005719=PMID:11124534, GO:0019904=PMID:9636147, GO:0005819=PMID:11101528, GO:0005637=PMID:8663349, GO:0005634=PMID:17540172, GO:0005635=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0042802=PMID:21888893, GO:0005720=PMID:11124534, GO:0006338=PMID:8663349, GO:0000779=GO_REF:0000024, GO:0031618=GO_REF:0000024, GO:0019899=PMID:19486527, GO:0045892=PMID:9636147, GO:0000785=PMID:11101528} Q13185 Chromobox protein homolog 3 protein 20081022 {GO:0005515=IPI, GO:0005719=IDA, GO:0019904=IPI, GO:0005819=IDA, GO:0005637=NAS, GO:0005634=IDA, GO:0005635=ISS, GO:0006351=IEA, GO:0042802=IPI, GO:0005720=IDA, GO:0006338=NAS, GO:0000779=ISS, GO:0031618=ISS, GO:0019899=IPI, GO:0045892=IMP, GO:0000785=IDA} chromatin remodeling, negative regulation of transcription, DNA-dependent, transcription, DNA-dependent chromatin, condensed chromosome, centromeric region, nuclear centromeric heterochromatin, nuclear envelope, nuclear euchromatin, nuclear heterochromatin, nuclear inner membrane, nucleus, spindle enzyme binding, identical protein binding, protein binding, protein domain specific binding Human CBX4 HPA UniProtKB {GO:0031519=PMID:21282530, GO:0035102=PMID:19636380, GO:0051219=GO_REF:0000019, GO:0005515=PMID:22078878, GO:0032183=PMID:20176810, GO:0043066=PMID:9315667, GO:0003727=GO_REF:0000019, GO:0005794=GO_REF:0000052, GO:0044212=GO_REF:0000019, GO:0003714=PMID:9315667, GO:0016874=GO_REF:0000037, GO:0016925=GO_REF:0000041, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000122=PMID:21282530, GO:0035064=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0016607=GO_REF:0000039, GO:0003682=GO_REF:0000019, GO:0019899=PMID:17087506, GO:0045892=PMID:18567530, GO:0016568=GO_REF:0000037} O00257 E3 SUMO-protein ligase CBX4 protein 20101115 {GO:0031519=IDA, GO:0035102=IDA, GO:0051219=IEA, GO:0005515=IPI, GO:0032183=IDA, GO:0043066=TAS, GO:0003727=IEA, GO:0005794=IDA, GO:0044212=IEA, GO:0003714=TAS, GO:0016874=IEA, GO:0016925=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0000122=IMP, GO:0035064=IEA, GO:0006351=IEA, GO:0005737=IDA, GO:0016607=IEA, GO:0003682=IEA, GO:0019899=IPI, GO:0045892=IDA, GO:0016568=IEA} chromatin modification, negative regulation of apoptotic process, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, protein sumoylation, transcription, DNA-dependent Golgi apparatus, PRC1 complex, PcG protein complex, cytoplasm, nuclear speck, nucleolus, nucleus SUMO binding, chromatin binding, enzyme binding, ligase activity, methylated histone residue binding, phosphoprotein binding, protein binding, single-stranded RNA binding, transcription corepressor activity, transcription regulatory region DNA binding Human CBX5 HPA UniProtKB {GO:0005515=PMID:9636147, GO:0010369=GO_REF:0000019, GO:0042826=GO_REF:0000019, GO:0005730=PMID:9636146, GO:0005634=GO_REF:0000052, GO:0005635=PMID:8663349, GO:0035064=PMID:21029866, GO:0005737=GO_REF:0000052, GO:0005720=PMID:8663349, GO:0035097=GO_REF:0000024, GO:0000118=GO_REF:0000024, GO:0007596=Reactome:REACT_604, GO:0016605=PMID:9636146, GO:0019048=GO_REF:0000037, GO:0003682=GO_REF:0000019, GO:0017053=GO_REF:0000024, GO:0070491=GO_REF:0000024, GO:0000776=GO_REF:0000019, GO:0005654=Reactome:REACT_25059, GO:0031618=PMID:16177824, GO:0019899=PMID:19486527, GO:0030674=GO_REF:0000024, GO:0045892=PMID:9636147} P45973 Chromobox protein homolog 5 protein 20090616 {GO:0005515=IPI, GO:0010369=IEA, GO:0042826=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005635=TAS, GO:0035064=IDA, GO:0005737=IDA, GO:0005720=TAS, GO:0035097=ISS, GO:0000118=ISS, GO:0007596=TAS, GO:0016605=IMP, GO:0019048=IEA, GO:0003682=IEA, GO:0017053=ISS, GO:0070491=ISS, GO:0000776=IEA, GO:0005654=TAS, GO:0031618=NAS, GO:0019899=IPI, GO:0030674=ISS, GO:0045892=IMP} blood coagulation, negative regulation of transcription, DNA-dependent, virus-host interaction PML body, chromocenter, cytoplasm, histone deacetylase complex, histone methyltransferase complex, kinetochore, nuclear centromeric heterochromatin, nuclear envelope, nuclear heterochromatin, nucleolus, nucleoplasm, nucleus, transcriptional repressor complex chromatin binding, enzyme binding, histone deacetylase binding, methylated histone residue binding, protein binding, protein binding, bridging, repressing transcription factor binding Human CBX6 IntAct UniProtKB {GO:0005515=PMID:21282530, GO:0031519=PMID:21282530, GO:0000792=GO_REF:0000019, GO:0003727=GO_REF:0000019, GO:0005634=PMID:21282530, GO:0000122=PMID:21282530, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} O95503 Chromobox protein homolog 6 protein 20130415 {GO:0005515=IPI, GO:0031519=IDA, GO:0000792=IEA, GO:0003727=IEA, GO:0005634=IDA, GO:0000122=IMP, GO:0006351=IEA, GO:0016568=IEA} chromatin modification, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent PcG protein complex, heterochromatin, nucleus protein binding, single-stranded RNA binding Human UniProtKB:Q99496 CBX7 IntAct UniProtKB {GO:0031519=PMID:21282530, GO:0035102=GO_REF:0000024, GO:0005515=PMID:21282530, GO:0000792=GO_REF:0000019, GO:0000790=PMID:19636380, GO:0003727=GO_REF:0000019, GO:0005634=PMID:21282530, GO:0000122=PMID:19636380, GO:0035064=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} O95931 Chromobox protein homolog 7 protein 20130415 {GO:0031519=IDA, GO:0035102=ISS, GO:0005515=IPI, GO:0000792=IEA, GO:0000790=IDA, GO:0003727=IEA, GO:0005634=IDA, GO:0000122=IMP, GO:0035064=IEA, GO:0006351=IEA, GO:0016568=IEA} chromatin modification, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent PRC1 complex, PcG protein complex, heterochromatin, nuclear chromatin, nucleus methylated histone residue binding, protein binding, single-stranded RNA binding Human UniProtKB:Q9BYE7 CBX8 HPA UniProtKB {GO:0000792=GO_REF:0000019, GO:0031519=PMID:21282530, GO:0035102=PMID:19636380, GO:0005515=PMID:22094252, GO:0003727=GO_REF:0000019, GO:0004842=GO_REF:0000019, GO:0000790=PMID:19636380, GO:0016574=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0000151=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0035064=PMID:21029866, GO:0000122=PMID:19636380, GO:0006351=GO_REF:0000037} Q9HC52 Chromobox protein homolog 8 protein 20101115 {GO:0000792=IEA, GO:0031519=IDA, GO:0035102=IDA, GO:0005515=IPI, GO:0003727=IEA, GO:0004842=IEA, GO:0000790=IDA, GO:0016574=IEA, GO:0005730=IDA, GO:0000151=IEA, GO:0005634=IDA, GO:0035064=IDA, GO:0000122=IMP, GO:0006351=IEA} histone ubiquitination, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent PRC1 complex, PcG protein complex, heterochromatin, nuclear chromatin, nucleolus, nucleus, ubiquitin ligase complex methylated histone residue binding, protein binding, single-stranded RNA binding, ubiquitin-protein ligase activity NOT Human CBY1 UniProtKB UniProtKB {GO:0005515=PMID:15194699, GO:0005802=PMID:15194699, GO:0005794=GO_REF:0000039, GO:0008013=PMID:12712206, GO:0030178=PMID:12712206, GO:0005634=PMID:12712206, GO:0042802=PMID:15194699, GO:0042384=GO_REF:0000019, GO:0008104=PMID:15194699, GO:0016607=GO_REF:0000039, GO:0045444=GO_REF:0000024, GO:0005932=GO_REF:0000019, GO:0055007=GO_REF:0000024, GO:0090090=GO_REF:0000019, GO:0045892=PMID:12712206} Q9Y3M2 Protein chibby homolog 1 protein 20050322 {GO:0005515=IPI, GO:0005802=IDA, GO:0005794=IEA, GO:0008013=IDA, GO:0030178=IDA, GO:0005634=IDA, GO:0042802=IPI, GO:0042384=IEA, GO:0008104=IMP, GO:0016607=IEA, GO:0045444=ISS, GO:0005932=IEA, GO:0055007=ISS, GO:0090090=IEA, GO:0045892=IDA} cardiac muscle cell differentiation, cilium assembly, fat cell differentiation, negative regulation of Wnt receptor signaling pathway, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of transcription, DNA-dependent, protein localization Golgi apparatus, microtubule basal body, nuclear speck, nucleus, trans-Golgi network beta-catenin binding, identical protein binding, protein binding Human UniProtKB:Q9Y3M2 CC2D1A GOC UniProtKB {GO:0007165=PMID:12761501, GO:0001078=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0005815=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0004871=PMID:12761501, GO:0043123=PMID:12761501, GO:0000978=GO_REF:0000019} Q6P1N0 Coiled-coil and C2 domain-containing protein 1A protein 20130413 {GO:0007165=IMP, GO:0001078=IEA, GO:0005737=IEA, GO:0005815=IEA, GO:0005634=IEA, GO:0004871=IMP, GO:0043123=IMP, GO:0000978=IEA} positive regulation of I-kappaB kinase/NF-kappaB cascade, signal transduction cytoplasm, microtubule organizing center, nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, signal transducer activity Human CC2D1B UniProtKB UniProtKB {GO:0001078=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0000978=GO_REF:0000019} Q5T0F9 Coiled-coil and C2 domain-containing protein 1B protein 20130413 {GO:0001078=IEA, GO:0005634=IEA, GO:0000978=IEA} nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription Human UniProtKB-SubCell:SL-0191 CC2D2A UniProtKB UniProtKB {GO:0042384=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0035869=GO_REF:0000024, GO:0060271=GO_REF:0000024, GO:0036038=GO_REF:0000024, GO:0005932=GO_REF:0000039, GO:0007224=GO_REF:0000024} Q9P2K1 Coiled-coil and C2 domain-containing protein 2A protein 20120113 {GO:0042384=ISS, GO:0005737=IEA, GO:0035869=ISS, GO:0060271=ISS, GO:0036038=ISS, GO:0005932=IEA, GO:0007224=ISS} cilium assembly, cilium morphogenesis, smoothened signaling pathway TCTN-B9D complex, ciliary transition zone, cytoplasm, microtubule basal body Human UniProtKB:Q8CFW7 CCAR1 IntAct UniProtKB {GO:0005515=PMID:20594350, GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0048471=GO_REF:0000039, GO:0007049=GO_REF:0000037, GO:0006355=GO_REF:0000037, GO:0030374=PMID:18722177, GO:0000398=Reactome:REACT_467, GO:0006915=GO_REF:0000037, GO:0005654=Reactome:REACT_1935, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q8IX12 Cell division cycle and apoptosis regulator protein 1 protein 20130415 {GO:0005515=IPI, GO:0008380=TAS, GO:0010467=TAS, GO:0048471=IEA, GO:0007049=IEA, GO:0006355=IEA, GO:0030374=IGI, GO:0000398=TAS, GO:0006915=IEA, GO:0005654=TAS, GO:0003676=IEA, GO:0006351=IEA} RNA splicing, apoptotic process, cell cycle, gene expression, mRNA splicing, via spliceosome, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleoplasm, perinuclear region of cytoplasm ligand-dependent nuclear receptor transcription coactivator activity, nucleic acid binding, protein binding Human UniProtKB:Q9GZV5 CCBE1 UniProtKB UniProtKB {GO:0001946=GO_REF:0000024, GO:0005581=GO_REF:0000037, GO:0005509=GO_REF:0000002, GO:0002040=GO_REF:0000024, GO:0048845=GO_REF:0000024} Q6UXH8 Collagen and calcium-binding EGF domain-containing protein 1 protein 20090421 {GO:0001946=ISS, GO:0005581=IEA, GO:0005509=IEA, GO:0002040=ISS, GO:0048845=ISS} lymphangiogenesis, sprouting angiogenesis, venous blood vessel morphogenesis collagen calcium ion binding Human UniProtKB:A8WGB1 CCBL1 HPA UniProtKB {GO:0006559=Reactome:REACT_1786, GO:0006569=Reactome:REACT_916, GO:0070189=PMID:19338303, GO:0009058=GO_REF:0000002, GO:0047312=Reactome:REACT_25224, GO:0008483=PMID:7883047, GO:0005730=GO_REF:0000052, GO:0047804=GO_REF:0000003, GO:0008652=Reactome:REACT_238, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0016829=GO_REF:0000038, GO:0042803=PMID:15364907, GO:0005829=Reactome:REACT_121130, GO:0034641=Reactome:REACT_13, GO:0097053=GO_REF:0000041, GO:0005737=GO_REF:0000052, GO:0030170=GO_REF:0000002, GO:0006575=PMID:7883047, GO:0047316=GO_REF:0000003, GO:0016212=Reactome:REACT_25349, GO:0036141=Reactome:REACT_121130, GO:0047945=Reactome:REACT_25034} Q5T278 Kynurenine--oxoglutarate transaminase 1 protein 20100326 {GO:0006559=TAS, GO:0006569=TAS, GO:0070189=IDA, GO:0009058=IEA, GO:0047312=EXP, GO:0008483=TAS, GO:0005730=IDA, GO:0047804=IEA, GO:0008652=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0003824=IEA, GO:0016829=IEA, GO:0042803=IPI, GO:0005829=TAS, GO:0034641=TAS, GO:0097053=IEA, GO:0005737=IDA, GO:0030170=IEA, GO:0006575=TAS, GO:0047316=IEA, GO:0016212=EXP, GO:0036141=TAS, GO:0047945=EXP} L-kynurenine catabolic process, L-phenylalanine catabolic process, biosynthetic process, cellular amino acid biosynthetic process, cellular modified amino acid metabolic process, cellular nitrogen compound metabolic process, kynurenine metabolic process, small molecule metabolic process, tryptophan catabolic process cytoplasm, cytosol, nucleolus, nucleus L-glutamine:pyruvate aminotransferase activity, L-phenylalanine-oxaloacetate transaminase activity, L-phenylalanine:pyruvate aminotransferase activity, catalytic activity, cysteine-S-conjugate beta-lyase activity, glutamine-phenylpyruvate transaminase activity, kynurenine-oxoglutarate transaminase activity, lyase activity, protein homodimerization activity, pyridoxal phosphate binding, transaminase activity Human CCBL2 Reactome UniProtKB {GO:0006520=GO_REF:0000024, GO:0070189=GO_REF:0000024, GO:0006569=Reactome:REACT_916, GO:0009058=GO_REF:0000002, GO:0047804=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0042803=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0034641=Reactome:REACT_13, GO:0030170=GO_REF:0000002, GO:0006103=GO_REF:0000019, GO:0016212=GO_REF:0000024, GO:0047315=GO_REF:0000024} Q6YP21 Kynurenine--oxoglutarate transaminase 3 protein 20130213 {GO:0006520=ISS, GO:0070189=ISS, GO:0006569=TAS, GO:0009058=IEA, GO:0047804=IEA, GO:0044281=TAS, GO:0042803=IEA, GO:0005739=IEA, GO:0034641=TAS, GO:0030170=IEA, GO:0006103=IEA, GO:0016212=ISS, GO:0047315=ISS} 2-oxoglutarate metabolic process, biosynthetic process, cellular amino acid metabolic process, cellular nitrogen compound metabolic process, kynurenine metabolic process, small molecule metabolic process, tryptophan catabolic process mitochondrion cysteine-S-conjugate beta-lyase activity, kynurenine-glyoxylate transaminase activity, kynurenine-oxoglutarate transaminase activity, protein homodimerization activity, pyridoxal phosphate binding Human CCBP2 GOC UniProtKB {GO:0043130=GO_REF:0000002, GO:0070098=PMID:9364936, GO:0005886=Reactome:REACT_21265, GO:0007275=PMID:9364936, GO:0007204=GO_REF:0000002, GO:0019958=GO_REF:0000002, GO:0019957=GO_REF:0000019, GO:0006955=PMID:9364936, GO:0006935=GO_REF:0000002, GO:0007186=PMID:9364936, GO:0016494=GO_REF:0000002, GO:0005887=PMID:9364936, GO:0004950=PMID:9364936, GO:0016493=GO_REF:0000019, GO:0042119=GO_REF:0000002} O00590 Chemokine-binding protein 2 protein 20130413 {GO:0043130=IEA, GO:0070098=TAS, GO:0005886=TAS, GO:0007275=TAS, GO:0007204=IEA, GO:0019958=IEA, GO:0019957=IEA, GO:0006955=TAS, GO:0006935=IEA, GO:0007186=TAS, GO:0016494=IEA, GO:0005887=TAS, GO:0004950=TAS, GO:0016493=IEA, GO:0042119=IEA} G-protein coupled receptor signaling pathway, chemokine-mediated signaling pathway, chemotaxis, elevation of cytosolic calcium ion concentration, immune response, multicellular organismal development, neutrophil activation integral to plasma membrane, plasma membrane C-C chemokine binding, C-C chemokine receptor activity, C-X-C chemokine binding, C-X-C chemokine receptor activity, chemokine receptor activity, ubiquitin binding Human CCDC101 BHF-UCL UniProtKB {GO:0006355=GO_REF:0000037, GO:0071169=PMID:20850016, GO:0043966=PMID:18838386, GO:0005671=PMID:18838386, GO:0035064=PMID:20850016, GO:0006351=GO_REF:0000037, GO:0070461=PMID:18838386} Q96ES7 SAGA-associated factor 29 homolog protein 20101105 {GO:0006355=IEA, GO:0071169=TAS, GO:0043966=IDA, GO:0005671=IDA, GO:0035064=IDA, GO:0006351=IEA, GO:0070461=IDA} establishment of protein localization to chromatin, histone H3 acetylation, regulation of transcription, DNA-dependent, transcription, DNA-dependent Ada2/Gcn5/Ada3 transcription activator complex, SAGA-type complex methylated histone residue binding Human CCDC104 null null {} null null null null {} null null null CCDC106 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039} Q9BWC9 Coiled-coil domain-containing protein 106 protein 20130413 {GO:0005634=IEA} nucleus Human UniProtKB-SubCell:SL-0191 CCDC107 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8WV48 Coiled-coil domain-containing protein 107 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 CCDC109B UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9NWR8 Coiled-coil domain-containing protein 109B protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 CCDC11 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q96M91 Coiled-coil domain-containing protein 11 protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human CCDC110 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0043231=GO_REF:0000052} Q8TBZ0 Coiled-coil domain-containing protein 110 protein 20110516 {GO:0005737=IDA, GO:0005794=IDA, GO:0005886=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0043231=IDA} Golgi apparatus, cytoplasm, intracellular membrane-bounded organelle, nucleolus, nucleus, plasma membrane Human CCDC112 null null {} null null null null {} null null null CCDC113 HPA UniProtKB {GO:0043234=GO_REF:0000054, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9H0I3 Coiled-coil domain-containing protein 113 protein 20110516 {GO:0043234=IDA, GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA} cytoplasm, nucleolus, nucleus, protein complex Human CCDC115 UniProtKB UniProtKB {GO:0005764=GO_REF:0000039, GO:0005768=GO_REF:0000039} Q96NT0 Coiled-coil domain-containing protein 115 protein 20130413 {GO:0005764=IEA, GO:0005768=IEA} endosome, lysosome Human UniProtKB-SubCell:SL-0101 CCDC116 null null {} null null null null {} null null null CCDC117 null null {} null null null null {} null null null CCDC12 null null {} null null null null {} null null null CCDC120 null null {} null null null null {} null null null CCDC124 null null {} null null null null {} null null null CCDC127 null null {} null null null null {} null null null CCDC130 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0005575=GO_REF:0000015, GO:0009615=PMID:3203696} P13994 Coiled-coil domain-containing protein 130 protein 20130415 {GO:0005515=IPI, GO:0005575=ND, GO:0009615=IEP} response to virus cellular_component protein binding Human UniProtKB:P49910 CCDC132 null null {} null null null null {} null null null CCDC134 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q9H6E4 Coiled-coil domain-containing protein 134 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 CCDC136 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q96JN2 Coiled-coil domain-containing protein 136 protein 20130413 {GO:0005739=IEA, GO:0016021=IEA} integral to membrane, mitochondrion Human Ensembl:ENSMUSP00000093789 CCDC137 null null {} null null null null {} null null null CCDC138 null null {} null null null null {} null null null CCDC14 UniProtKB UniProtKB {GO:0005813=PMID:21399614} Q49A88 Coiled-coil domain-containing protein 14 protein 20110517 {GO:0005813=IDA} centrosome Human CCDC141 IntAct UniProtKB {GO:0005515=PMID:12812986} Q6ZP82 Coiled-coil domain-containing protein 141 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:Q9NRI5 CCDC144A null null {} null null null null {} null null null CCDC144NL null null {} null null null null {} null null null CCDC146 null null {} null null null null {} null null null CCDC147 null null {} null null null null {} null null null CCDC148 null null {} null null null null {} null null null CCDC149 null null {} null null null null {} null null null CCDC15 UniProtKB UniProtKB {GO:0005813=PMID:21399614} Q0P6D6 Coiled-coil domain-containing protein 15 protein 20110517 {GO:0005813=IDA} centrosome Human CCDC155 HPA UniProtKB {GO:0005640=GO_REF:0000039, GO:0000781=GO_REF:0000024, GO:0005794=GO_REF:0000052, GO:0006470=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0008138=GO_REF:0000002, GO:0043231=GO_REF:0000052} Q8N6L0 Protein KASH5 protein 20100326 {GO:0005640=IEA, GO:0000781=ISS, GO:0005794=IDA, GO:0006470=IEA, GO:0005509=IEA, GO:0016021=IEA, GO:0008138=IEA, GO:0043231=IDA} protein dephosphorylation Golgi apparatus, chromosome, telomeric region, integral to membrane, intracellular membrane-bounded organelle, nuclear outer membrane calcium ion binding, protein tyrosine/serine/threonine phosphatase activity Human CCDC158 null null {} null null null null {} null null null CCDC159 null null {} null null null null {} null null null CCDC167 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9P0B6 Coiled-coil domain-containing protein 167 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 CCDC168 null null {} null null null null {} null null null CCDC17 null null {} null null null null {} null null null CCDC18 null null {} null null null null {} null null null CCDC19 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0005634=PMID:10524255} Q9UL16 Coiled-coil domain-containing protein 19, mitochondrial protein 20120803 {GO:0005739=IEA, GO:0005634=NAS} mitochondrion, nucleus Human CCDC22 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} O60826 Coiled-coil domain-containing protein 22 protein 20080623 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human CCDC23 MGI UniProtKB {GO:0010596=PMID:20736312, GO:0009306=PMID:20736312, GO:0045177=PMID:20736312, GO:0031397=PMID:20736312} Q8N300 Coiled-coil domain-containing protein 23 protein 20120321 {GO:0010596=IGI, GO:0009306=IDA, GO:0045177=IDA, GO:0031397=IDA} negative regulation of endothelial cell migration, negative regulation of protein ubiquitination, protein secretion apical part of cell Human CCDC24 null null {} null null null null {} null null null CCDC25 null null {} null null null null {} null null null CCDC28A null null {} null null null null {} null null null CCDC28B UniProtKB UniProtKB {GO:0005515=PMID:16327777, GO:0042384=PMID:23015189, GO:0005813=PMID:16327777, GO:0005737=GO_REF:0000037} Q9BUN5 Coiled-coil domain-containing protein 28B protein 20121008 {GO:0005515=IPI, GO:0042384=IMP, GO:0005813=IDA, GO:0005737=IEA} cilium assembly centrosome, cytoplasm protein binding Human CCDC33 IntAct UniProtKB {GO:0005515=PMID:16189514} Q8N5R6 Coiled-coil domain-containing protein 33 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:Q96ED9 CCDC39 BHF-UCL UniProtKB {GO:0001947=PMID:22693285, GO:0060287=PMID:21131972, GO:0060286=PMID:21131972, GO:0035469=PMID:22693285, GO:0071910=PMID:22693285, GO:0030324=PMID:22693285, GO:0060285=PMID:21131972, GO:0070286=PMID:21131972, GO:0035085=PMID:21131974, GO:0005856=GO_REF:0000037, GO:0071907=PMID:22693285} Q9UFE4 Coiled-coil domain-containing protein 39 protein 20130301 {GO:0001947=IMP, GO:0060287=IMP, GO:0060286=IMP, GO:0035469=IMP, GO:0071910=IMP, GO:0030324=IMP, GO:0060285=IMP, GO:0070286=IMP, GO:0035085=IDA, GO:0005856=IEA, GO:0071907=IMP} axonemal dynein complex assembly, ciliary cell motility, determination of digestive tract left/right asymmetry, determination of liver left/right asymmetry, determination of pancreatic left/right asymmetry, epithelial cilium movement involved in determination of left/right asymmetry, flagellar cell motility, heart looping, lung development cilium axoneme, cytoskeleton Human CCDC40 BHF-UCL UniProtKB {GO:0001947=PMID:22693285, GO:0060287=PMID:21131974, GO:0003674=GO_REF:0000015, GO:0060286=GO_REF:0000019, GO:0005929=GO_REF:0000024, GO:0035469=PMID:22693285, GO:0005737=GO_REF:0000024, GO:0071910=PMID:22693285, GO:0030324=PMID:22693285, GO:0060285=GO_REF:0000019, GO:0070286=PMID:21131974, GO:0071907=PMID:22693285} Q4G0X9 Coiled-coil domain-containing protein 40 protein 20120529 {GO:0001947=IMP, GO:0060287=IMP, GO:0003674=ND, GO:0060286=IEA, GO:0005929=ISS, GO:0035469=IMP, GO:0005737=ISS, GO:0071910=IMP, GO:0030324=IMP, GO:0060285=IEA, GO:0070286=IMP, GO:0071907=IMP} axonemal dynein complex assembly, ciliary cell motility, determination of digestive tract left/right asymmetry, determination of liver left/right asymmetry, determination of pancreatic left/right asymmetry, epithelial cilium movement involved in determination of left/right asymmetry, flagellar cell motility, heart looping, lung development cilium, cytoplasm molecular_function Human CCDC41 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q9Y592 Coiled-coil domain-containing protein 41 protein 20101125 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human CCDC42 null null {} null null null null {} null null null CCDC43 null null {} null null null null {} null null null CCDC47 IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0008150=GO_REF:0000015, GO:0006983=GO_REF:0000019, GO:0005783=GO_REF:0000019, GO:0005509=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0009790=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0009791=GO_REF:0000019, GO:0055074=GO_REF:0000019} Q96A33 Coiled-coil domain-containing protein 47 protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0006983=IEA, GO:0005783=IEA, GO:0005509=IEA, GO:0005575=ND, GO:0009790=IEA, GO:0016021=IEA, GO:0009791=IEA, GO:0055074=IEA} ER overload response, biological_process, calcium ion homeostasis, embryo development, post-embryonic development cellular_component, endoplasmic reticulum, integral to membrane calcium ion binding, protein binding Human UniProtKB:Q99J34 CCDC50 HPA UniProtKB {GO:0005515=PMID:18029035, GO:0005737=GO_REF:0000052} Q8IVM0 Coiled-coil domain-containing protein 50 protein 20080818 {GO:0005515=IPI, GO:0005737=IDA} cytoplasm protein binding Human CCDC51 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0016021=GO_REF:0000037} Q96ER9 Coiled-coil domain-containing protein 51 protein 20081203 {GO:0005739=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0016021=IEA} integral to membrane, mitochondrion, nucleolus, nucleus Human CCDC53 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0008150=GO_REF:0000015, GO:0071203=PMID:19922875} Q9Y3C0 WASH complex subunit CCDC53 protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0071203=IDA} biological_process WASH complex protein binding Human UniProtKB:Q96EZ8 CCDC57 null null {} null null null null {} null null null CCDC58 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019} Q4VC31 Coiled-coil domain-containing protein 58 protein 20130413 {GO:0005739=IEA} mitochondrion Human Ensembl:ENSMUSP00000125874 CCDC59 IntAct UniProtKB {GO:0005515=PMID:11152647, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q9P031 Thyroid transcription factor 1-associated protein 26 protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0005634=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus protein binding Human UniProtKB:P43699 CCDC6 HPA UniProtKB {GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0017124=GO_REF:0000037, GO:0005200=PMID:8058316, GO:0005856=GO_REF:0000039} Q16204 Coiled-coil domain-containing protein 6 protein 20110516 {GO:0008150=ND, GO:0005737=IDA, GO:0017124=IEA, GO:0005200=TAS, GO:0005856=IEA} biological_process cytoplasm, cytoskeleton SH3 domain binding, structural constituent of cytoskeleton Human CCDC60 null null {} null null null null {} null null null CCDC64B ENSEMBL UniProtKB {GO:0017137=GO_REF:0000019} A1A5D9 Bicaudal D-related protein 2 protein 20130413 {GO:0017137=IEA} Rab GTPase binding Human Ensembl:ENSMUSP00000053808 CCDC66 null null {} null null null null {} null null null CCDC67 null null {} null null null null {} null null null CCDC68 null null {} null null null null {} null null null CCDC69 null null {} null null null null {} null null null CCDC7 null null {} null null null null {} null null null CCDC71 null null {} null null null null {} null null null CCDC77 UniProtKB UniProtKB {GO:0005813=PMID:21399614} Q9BR77 Coiled-coil domain-containing protein 77 protein 20110517 {GO:0005813=IDA} centrosome Human CCDC78 ENSEMBL UniProtKB {GO:0042383=PMID:22818856, GO:0005737=GO_REF:0000019, GO:0048471=PMID:22818856, GO:0016529=PMID:22818856, GO:0003009=PMID:22818856} I3L158 Coiled-coil domain-containing protein 78 protein 20130413 {GO:0042383=IDA, GO:0005737=IEA, GO:0048471=IDA, GO:0016529=IDA, GO:0003009=IMP} skeletal muscle contraction cytoplasm, perinuclear region of cytoplasm, sarcolemma, sarcoplasmic reticulum Human Ensembl:ENSMUSP00000093155 CCDC8 LIFEdb UniProtKB {GO:0005886=GO_REF:0000054, GO:0010923=PMID:19389623} Q9H0W5 Coiled-coil domain-containing protein 8 protein 20100607 {GO:0005886=IDA, GO:0010923=IDA} negative regulation of phosphatase activity plasma membrane Human CCDC80 ENSEMBL UniProtKB {GO:0030198=GO_REF:0000019, GO:0010811=GO_REF:0000019, GO:0005614=GO_REF:0000019, GO:0001968=GO_REF:0000019, GO:0008201=GO_REF:0000019, GO:0005604=GO_REF:0000019} Q76M96 Coiled-coil domain-containing protein 80 protein 20130413 {GO:0030198=IEA, GO:0010811=IEA, GO:0005614=IEA, GO:0001968=IEA, GO:0008201=IEA, GO:0005604=IEA} extracellular matrix organization, positive regulation of cell-substrate adhesion basement membrane, interstitial matrix fibronectin binding, heparin binding Human Ensembl:ENSMUSP00000097097 CCDC82 null null {} null null null null {} null null null CCDC85A null null {} null null null null {} null null null CCDC85B IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0030308=PMID:17873903, GO:0005813=PMID:17014843, GO:0005737=GO_REF:0000037, GO:0045599=GO_REF:0000024, GO:0005634=PMID:17873903, GO:0045892=PMID:17014843, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q15834 Coiled-coil domain-containing protein 85B protein 20130415 {GO:0005515=IPI, GO:0030308=IDA, GO:0005813=IDA, GO:0005737=IEA, GO:0045599=ISS, GO:0005634=IDA, GO:0045892=IDA, GO:0030154=IEA, GO:0006351=IEA} cell differentiation, negative regulation of cell growth, negative regulation of fat cell differentiation, negative regulation of transcription, DNA-dependent, transcription, DNA-dependent centrosome, cytoplasm, nucleus protein binding Human UniProtKB:Q9UFG5 CCDC85C ENSEMBL UniProtKB {GO:0043296=GO_REF:0000019, GO:0021987=GO_REF:0000019, GO:0005923=GO_REF:0000039} G3V5D5 Coiled-coil domain-containing protein 85C protein 20130413 {GO:0043296=IEA, GO:0021987=IEA, GO:0005923=IEA} cerebral cortex development apical junction complex, tight junction Human Ensembl:ENSMUSP00000125757 CCDC86 HPA UniProtKB {GO:0019048=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9H6F5 Coiled-coil domain-containing protein 86 protein 20111111 {GO:0019048=IEA, GO:0005730=IDA, GO:0005634=IDA} virus-host interaction nucleolus, nucleus Human CCDC87 InterPro UniProtKB {GO:0008017=GO_REF:0000002, GO:0000910=GO_REF:0000002, GO:0000226=GO_REF:0000002} Q9NVE4 Coiled-coil domain-containing protein 87 protein 20130413 {GO:0008017=IEA, GO:0000910=IEA, GO:0000226=IEA} cytokinesis, microtubule cytoskeleton organization microtubule binding Human InterPro:IPR007145 CCDC88A UniProtKB UniProtKB {GO:0008017=GO_REF:0000024, GO:0005886=PMID:15882442, GO:0005783=PMID:15882442, GO:0030032=PMID:16139227, GO:0042803=PMID:16139227, GO:0005829=PMID:15749703, GO:0005737=GO_REF:0000002, GO:0042127=GO_REF:0000024, GO:0032956=PMID:16139227, GO:0032148=GO_REF:0000024, GO:0006275=GO_REF:0000024, GO:0031929=GO_REF:0000024, GO:0005794=PMID:15882442, GO:0000226=GO_REF:0000002, GO:0003779=PMID:16139227, GO:0031410=PMID:15882442, GO:0043422=PMID:16139227, GO:0030027=PMID:16139227, GO:0006260=GO_REF:0000037, GO:0016020=PMID:15749703, GO:0016477=PMID:16139227, GO:0010975=GO_REF:0000024, GO:0016023=GO_REF:0000039, GO:0001932=GO_REF:0000024, GO:0035091=PMID:16139227, GO:0016044=PMID:15882442} Q3V6T2 Girdin protein 20100304 {GO:0008017=ISS, GO:0005886=IDA, GO:0005783=IDA, GO:0030032=IMP, GO:0042803=IPI, GO:0005829=IDA, GO:0005737=IEA, GO:0042127=ISS, GO:0032956=IMP, GO:0032148=ISS, GO:0006275=ISS, GO:0031929=ISS, GO:0005794=IDA, GO:0000226=IEA, GO:0003779=IDA, GO:0031410=IDA, GO:0043422=IPI, GO:0030027=IDA, GO:0006260=IEA, GO:0016020=IDA, GO:0016477=IMP, GO:0010975=ISS, GO:0016023=IEA, GO:0001932=ISS, GO:0035091=IDA, GO:0016044=IDA} DNA replication, TOR signaling cascade, activation of protein kinase B activity, cell migration, cellular membrane organization, lamellipodium assembly, microtubule cytoskeleton organization, regulation of DNA replication, regulation of actin cytoskeleton organization, regulation of cell proliferation, regulation of neuron projection development, regulation of protein phosphorylation Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, cytoplasmic vesicle, cytosol, endoplasmic reticulum, lamellipodium, membrane, plasma membrane actin binding, microtubule binding, phosphatidylinositol binding, protein homodimerization activity, protein kinase B binding Human UniProtKB:Q5SNZ0 CCDC88B InterPro UniProtKB {GO:0008017=GO_REF:0000002, GO:0005737=GO_REF:0000002, GO:0000226=GO_REF:0000002} A6NC98 Coiled-coil domain-containing protein 88B protein 20130413 {GO:0008017=IEA, GO:0005737=IEA, GO:0000226=IEA} microtubule cytoskeleton organization cytoplasm microtubule binding Human InterPro:IPR008636 CCDC88C UniProtKB UniProtKB {GO:0031648=PMID:14750955, GO:0008017=GO_REF:0000002, GO:0005737=GO_REF:0000002, GO:0000226=GO_REF:0000002, GO:0051260=PMID:14750955, GO:0001932=PMID:14750955, GO:0043621=PMID:14750955, GO:0030165=PMID:14750955, GO:0016055=GO_REF:0000037} Q9P219 Protein Daple protein 20070418 {GO:0031648=ISS, GO:0008017=IEA, GO:0005737=IEA, GO:0000226=IEA, GO:0051260=ISS, GO:0001932=ISS, GO:0043621=ISS, GO:0030165=ISS, GO:0016055=IEA} Wnt receptor signaling pathway, microtubule cytoskeleton organization, protein destabilization, protein homooligomerization, regulation of protein phosphorylation cytoplasm PDZ domain binding, microtubule binding, protein self-association Human UniProtKB:Q6VGS5 CCDC89 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039} Q8N998 Coiled-coil domain-containing protein 89 protein 20130413 {GO:0005737=IEA, GO:0005634=IEA} cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 CCDC9 null null {} null null null null {} null null null CCDC90B HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0016021=GO_REF:0000037} Q9GZT6 Coiled-coil domain-containing protein 90B, mitochondrial protein 20081203 {GO:0005739=IDA, GO:0016021=IEA} integral to membrane, mitochondrion Human CCDC91 HPA UniProtKB {GO:0005794=GO_REF:0000052, GO:0016020=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0015031=GO_REF:0000037, GO:0042802=GO_REF:0000019} Q7Z6B0 Coiled-coil domain-containing protein 91 protein 20110516 {GO:0005794=IDA, GO:0016020=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0015031=IEA, GO:0042802=IEA} protein transport Golgi apparatus, membrane, nucleolus, nucleus identical protein binding Human CCDC92 UniProtKB UniProtKB {GO:0005515=PMID:22863007, GO:0005814=PMID:22863007} Q53HC0 Coiled-coil domain-containing protein 92 protein 20120816 {GO:0005515=IPI, GO:0005814=IDA} centriole protein binding Human CCDC93 null null {} null null null null {} null null null CCDC94 null null {} null null null null {} null null null CCDC97 null null {} null null null null {} null null null CCHCR1 HPA UniProtKB {GO:0005737=GO_REF:0000039, GO:0006611=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0030154=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q8TD31 Coiled-coil alpha-helical rod protein 1 protein 20120912 {GO:0005737=IEA, GO:0006611=IEA, GO:0007275=IEA, GO:0005634=IEA, GO:0030154=IEA, GO:0043231=IDA} cell differentiation, multicellular organismal development, protein export from nucleus cytoplasm, intracellular membrane-bounded organelle, nucleus Human CCIN UniProtKB UniProtKB {GO:0033150=GO_REF:0000039, GO:0005200=GO_REF:0000029, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000029, GO:0005856=GO_REF:0000029, GO:0030154=GO_REF:0000037} Q13939 Calicin protein 20021104 {GO:0033150=IEA, GO:0005200=NAS, GO:0007275=IEA, GO:0007283=NAS, GO:0005856=NAS, GO:0030154=IEA} cell differentiation, multicellular organismal development, spermatogenesis cytoskeletal calyx, cytoskeleton structural constituent of cytoskeleton Human CCK Reactome UniProtKB {GO:0030424=PMID:15152034, GO:0008284=GO_REF:0000019, GO:0032099=GO_REF:0000019, GO:0050731=GO_REF:0000019, GO:0001836=GO_REF:0000019, GO:0007409=PMID:15152034, GO:0005615=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0007205=GO_REF:0000019, GO:0043194=GO_REF:0000019, GO:0051901=GO_REF:0000019, GO:0043195=GO_REF:0000019, GO:0043203=GO_REF:0000019, GO:0043204=GO_REF:0000019, GO:0001662=GO_REF:0000019, GO:0032461=GO_REF:0000019, GO:0005184=PMID:15374756, GO:0043065=GO_REF:0000019, GO:0006919=GO_REF:0000019, GO:0005576=Reactome:REACT_22436, GO:0007165=PMID:10320330, GO:0005179=PMID:10320330, GO:0042755=PMID:15374756, GO:0001764=PMID:15152034, GO:0051930=GO_REF:0000019} P06307 Cholecystokinin protein 20081212 {GO:0030424=ISS, GO:0008284=IEA, GO:0032099=IEA, GO:0050731=IEA, GO:0001836=IEA, GO:0007409=ISS, GO:0005615=IEA, GO:0030425=IEA, GO:0007205=IEA, GO:0043194=IEA, GO:0051901=IEA, GO:0043195=IEA, GO:0043203=IEA, GO:0043204=IEA, GO:0001662=IEA, GO:0032461=IEA, GO:0005184=ISS, GO:0043065=IEA, GO:0006919=IEA, GO:0005576=TAS, GO:0007165=TAS, GO:0005179=TAS, GO:0042755=ISS, GO:0001764=ISS, GO:0051930=IEA} activation of cysteine-type endopeptidase activity involved in apoptotic process, axonogenesis, behavioral fear response, eating behavior, negative regulation of appetite, neuron migration, positive regulation of apoptotic process, positive regulation of cell proliferation, positive regulation of mitochondrial depolarization, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of protein oligomerization, protein kinase C-activating G-protein coupled receptor signaling pathway, regulation of sensory perception of pain, release of cytochrome c from mitochondria, signal transduction axon, axon hillock, axon initial segment, dendrite, extracellular region, extracellular space, perikaryon, terminal bouton hormone activity, neuropeptide hormone activity Human CCKAR Reactome UniProtKB {GO:0007631=PMID:8503909, GO:0005886=Reactome:REACT_22436, GO:0007584=PMID:8503909, GO:0005887=PMID:8343165, GO:0007586=PMID:8503909, GO:0007200=PMID:8343165, GO:0004951=GO_REF:0000002, GO:0030900=GO_REF:0000019, GO:0007409=GO_REF:0000019, GO:0001764=GO_REF:0000019, GO:0007204=PMID:8503909} P32238 Cholecystokinin receptor type A protein 20081212 {GO:0007631=TAS, GO:0005886=TAS, GO:0007584=TAS, GO:0005887=TAS, GO:0007586=TAS, GO:0007200=TAS, GO:0004951=IEA, GO:0030900=IEA, GO:0007409=IEA, GO:0001764=IEA, GO:0007204=TAS} axonogenesis, digestion, elevation of cytosolic calcium ion concentration, feeding behavior, forebrain development, neuron migration, phospholipase C-activating G-protein coupled receptor signaling pathway, response to nutrient integral to plasma membrane, plasma membrane cholecystokinin receptor activity Human CCKBR Reactome UniProtKB {GO:0015054=PMID:10913157, GO:0007631=PMID:7681836, GO:0008284=PMID:10913157, GO:0005886=Reactome:REACT_121113, GO:0008283=PMID:10400698, GO:0007586=PMID:7681836, GO:0007200=PMID:8455720, GO:0007204=PMID:10913157, GO:0046935=PMID:10400698, GO:0005887=PMID:10913157, GO:0004435=PMID:7681836, GO:0004951=PMID:7681836, GO:0016021=GO_REF:0000002, GO:0031741=PMID:8185642, GO:0007166=PMID:10913157, GO:0007600=PMID:7681836} P32239 Gastrin/cholecystokinin type B receptor protein 20120828 {GO:0015054=IDA, GO:0007631=TAS, GO:0008284=IDA, GO:0005886=TAS, GO:0008283=TAS, GO:0007586=TAS, GO:0007200=TAS, GO:0007204=IDA, GO:0046935=TAS, GO:0005887=IC, GO:0004435=TAS, GO:0004951=TAS, GO:0016021=IEA, GO:0031741=IDA, GO:0007166=NAS, GO:0007600=TAS} cell proliferation, cell surface receptor signaling pathway, digestion, elevation of cytosolic calcium ion concentration, feeding behavior, phospholipase C-activating G-protein coupled receptor signaling pathway, positive regulation of cell proliferation, sensory perception integral to membrane, integral to plasma membrane, plasma membrane 1-phosphatidylinositol-3-kinase regulator activity, cholecystokinin receptor activity, gastrin receptor activity, phosphatidylinositol phospholipase C activity, type B gastrin/cholecystokinin receptor binding Human CCL1 PINC UniProtKB {GO:0007165=PMID:9417093, GO:0008009=GO_REF:0000002, GO:0006955=GO_REF:0000002, GO:0006935=GO_REF:0000019, GO:0006874=PMID:9417093, GO:0016032=PMID:9417093, GO:0005615=GO_REF:0000037} P22362 C-C motif chemokine 1 protein 20030904 {GO:0007165=TAS, GO:0008009=IEA, GO:0006955=IEA, GO:0006935=IEA, GO:0006874=TAS, GO:0016032=TAS, GO:0005615=IEA} cellular calcium ion homeostasis, chemotaxis, immune response, signal transduction, viral reproduction extracellular space chemokine activity Human CCL11 BHF-UCL UniProtKB {GO:0032855=PMID:19525930, GO:0005615=GO_REF:0000019, GO:0006955=GO_REF:0000002, GO:0006954=PMID:10708591, GO:0006935=PMID:10706854, GO:0030838=PMID:19525930, GO:0007010=PMID:10072545, GO:0070670=GO_REF:0000019, GO:0007015=GO_REF:0000019, GO:0070371=GO_REF:0000019, GO:0007155=PMID:10201960, GO:0009314=PMID:10708591, GO:0008009=PMID:10072545, GO:0030335=PMID:19525930, GO:0006874=PMID:10415069, GO:0060763=GO_REF:0000019, GO:0005576=PMID:20041150, GO:0002544=GO_REF:0000019, GO:0009615=PMID:9558100, GO:0045766=GO_REF:0000019, GO:0007165=PMID:10706854, GO:0001938=PMID:19525930, GO:0002551=GO_REF:0000019, GO:0048245=PMID:10072545, GO:0006468=PMID:10706854, GO:0060444=GO_REF:0000019} P51671 Eotaxin protein 20120622 {GO:0032855=IDA, GO:0005615=IEA, GO:0006955=IEA, GO:0006954=TAS, GO:0006935=TAS, GO:0030838=IDA, GO:0007010=IDA, GO:0070670=IEA, GO:0007015=IEA, GO:0070371=IEA, GO:0007155=TAS, GO:0009314=TAS, GO:0008009=IDA, GO:0030335=IDA, GO:0006874=TAS, GO:0060763=IEA, GO:0005576=IDA, GO:0002544=IEA, GO:0009615=TAS, GO:0045766=IEA, GO:0007165=TAS, GO:0001938=IDA, GO:0002551=IEA, GO:0048245=IDA, GO:0006468=TAS, GO:0060444=IEA} ERK1 and ERK2 cascade, actin filament organization, branching involved in mammary gland duct morphogenesis, cell adhesion, cellular calcium ion homeostasis, chemotaxis, chronic inflammatory response, cytoskeleton organization, eosinophil chemotaxis, immune response, inflammatory response, mammary duct terminal end bud growth, mast cell chemotaxis, positive regulation of Rac GTPase activity, positive regulation of actin filament polymerization, positive regulation of angiogenesis, positive regulation of cell migration, positive regulation of endothelial cell proliferation, protein phosphorylation, response to interleukin-4, response to radiation, response to virus, signal transduction extracellular region, extracellular space chemokine activity Human CCL13 PINC UniProtKB {GO:0007165=PMID:9558100, GO:0008009=PMID:10072545, GO:0006955=GO_REF:0000002, GO:0006954=GO_REF:0000037, GO:0006935=PMID:9195948, GO:0007010=PMID:10072545, GO:0007267=PMID:9195948, GO:0006874=PMID:9195948, GO:0005102=PMID:9195948, GO:0048245=PMID:10072545, GO:0005576=GO_REF:0000002, GO:0005615=GO_REF:0000037} Q99616 C-C motif chemokine 13 protein 20030904 {GO:0007165=TAS, GO:0008009=IDA, GO:0006955=IEA, GO:0006954=IEA, GO:0006935=TAS, GO:0007010=IDA, GO:0007267=TAS, GO:0006874=TAS, GO:0005102=TAS, GO:0048245=IDA, GO:0005576=IEA, GO:0005615=IEA} cell-cell signaling, cellular calcium ion homeostasis, chemotaxis, cytoskeleton organization, eosinophil chemotaxis, immune response, inflammatory response, signal transduction extracellular region, extracellular space chemokine activity, receptor binding Human CCL14 PINC UniProtKB {GO:0008009=GO_REF:0000002, GO:0008284=PMID:8551235, GO:0006955=GO_REF:0000002, GO:0006874=PMID:8551235, GO:0005615=GO_REF:0000037} Q16627 C-C motif chemokine 14 protein 20030904 {GO:0008009=IEA, GO:0008284=TAS, GO:0006955=IEA, GO:0006874=TAS, GO:0005615=IEA} cellular calcium ion homeostasis, immune response, positive regulation of cell proliferation extracellular space chemokine activity Human CCL15 GOC UniProtKB {GO:0007165=PMID:9548457, GO:0008009=GO_REF:0000002, GO:0006955=GO_REF:0000002, GO:0006935=PMID:9600961, GO:0007267=PMID:9548457, GO:0006874=PMID:9346309, GO:0005102=PMID:9548457, GO:0005576=GO_REF:0000002, GO:0042056=PMID:15001559, GO:0008201=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0050918=PMID:15001559} Q16663 C-C motif chemokine 15 protein 20130413 {GO:0007165=TAS, GO:0008009=IEA, GO:0006955=IEA, GO:0006935=TAS, GO:0007267=TAS, GO:0006874=TAS, GO:0005102=TAS, GO:0005576=IEA, GO:0042056=IDA, GO:0008201=IEA, GO:0005615=IEA, GO:0050918=IDA} cell-cell signaling, cellular calcium ion homeostasis, chemotaxis, immune response, positive chemotaxis, signal transduction extracellular region, extracellular space chemoattractant activity, chemokine activity, heparin binding, receptor binding Human CCL16 GOC UniProtKB {GO:0008009=GO_REF:0000002, GO:0006955=GO_REF:0000002, GO:0007154=PMID:9642106, GO:0006954=GO_REF:0000037, GO:0006935=PMID:9642106, GO:0007267=PMID:9642106, GO:0005576=Reactome:REACT_22289, GO:0042056=PMID:15001559, GO:0005615=GO_REF:0000037, GO:0050918=PMID:15001559} O15467 C-C motif chemokine 16 protein 20130413 {GO:0008009=IEA, GO:0006955=IEA, GO:0007154=TAS, GO:0006954=IEA, GO:0006935=TAS, GO:0007267=TAS, GO:0005576=TAS, GO:0042056=IDA, GO:0005615=IEA, GO:0050918=IDA} cell communication, cell-cell signaling, chemotaxis, immune response, inflammatory response, positive chemotaxis extracellular region, extracellular space chemoattractant activity, chemokine activity Human CCL17 Reactome UniProtKB {GO:0008009=GO_REF:0000002, GO:0006955=GO_REF:0000002, GO:0006954=GO_REF:0000037, GO:0007186=PMID:8702936, GO:0006935=GO_REF:0000037, GO:0007267=PMID:8702936, GO:0005102=PMID:9743322, GO:0005576=Reactome:REACT_21265, GO:0007275=PMID:8702936, GO:0005615=GO_REF:0000037} Q92583 C-C motif chemokine 17 protein 20091020 {GO:0008009=IEA, GO:0006955=IEA, GO:0006954=IEA, GO:0007186=TAS, GO:0006935=IEA, GO:0007267=TAS, GO:0005102=TAS, GO:0005576=TAS, GO:0007275=TAS, GO:0005615=IEA} G-protein coupled receptor signaling pathway, cell-cell signaling, chemotaxis, immune response, inflammatory response, multicellular organismal development extracellular region, extracellular space chemokine activity, receptor binding Human CCL18 PINC UniProtKB {GO:0009607=PMID:9233607, GO:0007165=PMID:9233607, GO:0008009=GO_REF:0000002, GO:0006955=GO_REF:0000002, GO:0007154=PMID:9192897, GO:0006954=GO_REF:0000037, GO:0006935=GO_REF:0000037, GO:0007267=PMID:9233607, GO:0005615=GO_REF:0000037} P55774 C-C motif chemokine 18 protein 20031119 {GO:0009607=TAS, GO:0007165=TAS, GO:0008009=IEA, GO:0006955=IEA, GO:0007154=TAS, GO:0006954=IEA, GO:0006935=IEA, GO:0007267=TAS, GO:0005615=IEA} cell communication, cell-cell signaling, chemotaxis, immune response, inflammatory response, response to biotic stimulus, signal transduction extracellular space chemokine activity Human CCL19 BHF-UCL UniProtKB {GO:0042346=PMID:15059845, GO:0014070=GO_REF:0000019, GO:0051897=PMID:15778365, GO:0048020=PMID:20002784, GO:0031295=GO_REF:0000024, GO:0071731=PMID:16249377, GO:0046330=PMID:15778365, GO:0032735=GO_REF:0000024, GO:0097029=GO_REF:0000024, GO:0005615=GO_REF:0000037, GO:2000147=PMID:15778365, GO:0045807=GO_REF:0000024, GO:0006955=GO_REF:0000002, GO:0006954=PMID:14592837, GO:0007154=PMID:9153236, GO:0050921=GO_REF:0000024, GO:0043552=PMID:15778365, GO:0034695=PMID:14592837, GO:0050718=GO_REF:0000024, GO:0043089=GO_REF:0000024, GO:0072610=GO_REF:0000024, GO:0042102=GO_REF:0000024, GO:0045860=PMID:14592837, GO:0060491=GO_REF:0000024, GO:0048469=GO_REF:0000024, GO:0070374=PMID:15778365, GO:0043123=PMID:15059845, GO:0001771=GO_REF:0000024, GO:0008009=PMID:15778365, GO:0051209=PMID:14592837, GO:0032760=GO_REF:0000024, GO:2000549=GO_REF:0000024, GO:0002408=PMID:14592837, GO:0002407=PMID:15778365, GO:0006874=PMID:9153236, GO:0005576=Reactome:REACT_22289, GO:0007257=GO_REF:0000024, GO:0002606=GO_REF:0000024, GO:0009615=PMID:9153236, GO:0031735=PMID:10706668, GO:0032320=GO_REF:0000024, GO:0010560=GO_REF:0000024, GO:2000107=PMID:15059845, GO:0048260=GO_REF:0000024, GO:0045627=GO_REF:0000024, GO:0090023=PMID:21051556, GO:0001768=PMID:12729902, GO:0031732=GO_REF:0000024} Q99731 C-C motif chemokine 19 protein 20120404 {GO:0042346=IDA, GO:0014070=IEA, GO:0051897=IDA, GO:0048020=IPI, GO:0031295=ISS, GO:0071731=IDA, GO:0046330=IDA, GO:0032735=ISS, GO:0097029=ISS, GO:0005615=IEA, GO:2000147=IDA, GO:0045807=ISS, GO:0006955=IEA, GO:0006954=NAS, GO:0007154=TAS, GO:0050921=ISS, GO:0043552=IDA, GO:0034695=IDA, GO:0050718=ISS, GO:0043089=ISS, GO:0072610=ISS, GO:0042102=ISS, GO:0045860=IDA, GO:0060491=ISS, GO:0048469=ISS, GO:0070374=IDA, GO:0043123=IDA, GO:0001771=ISS, GO:0008009=IDA, GO:0051209=IDA, GO:0032760=ISS, GO:2000549=ISS, GO:0002408=IDA, GO:0002407=IDA, GO:0006874=TAS, GO:0005576=TAS, GO:0007257=ISS, GO:0002606=ISS, GO:0009615=TAS, GO:0031735=IDA, GO:0032320=ISS, GO:0010560=ISS, GO:2000107=IDA, GO:0048260=ISS, GO:0045627=ISS, GO:0090023=IDA, GO:0001768=IDA, GO:0031732=ISS} T cell costimulation, activation of JUN kinase activity, cell communication, cell maturation, cellular calcium ion homeostasis, dendritic cell chemotaxis, establishment of T cell polarity, immune response, immunological synapse formation, inflammatory response, interleukin-12 secretion, mature dendritic cell differentiation, myeloid dendritic cell chemotaxis, negative regulation of leukocyte apoptotic process, positive regulation of Cdc42 GTPase activity, positive regulation of ERK1 and ERK2 cascade, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of JNK cascade, positive regulation of NF-kappaB import into nucleus, positive regulation of Ras GTPase activity, positive regulation of T cell proliferation, positive regulation of T-helper 1 cell differentiation, positive regulation of cell motility, positive regulation of chemotaxis, positive regulation of dendritic cell antigen processing and presentation, positive regulation of dendritic cell dendrite assembly, positive regulation of endocytosis, positive regulation of glycoprotein biosynthetic process, positive regulation of interleukin-1 beta secretion, positive regulation of interleukin-12 production, positive regulation of neutrophil chemotaxis, positive regulation of phosphatidylinositol 3-kinase activity, positive regulation of protein kinase B signaling cascade, positive regulation of protein kinase activity, positive regulation of receptor-mediated endocytosis, positive regulation of tumor necrosis factor production, regulation of cell projection assembly, release of sequestered calcium ion into cytosol, response to nitric oxide, response to organic cyclic compound, response to prostaglandin E stimulus, response to virus extracellular region, extracellular space CCR chemokine receptor binding, CCR10 chemokine receptor binding, CCR7 chemokine receptor binding, chemokine activity Human UniProtKB:O70460 CCL2 BHF-UCL UniProtKB {GO:0009408=GO_REF:0000019, GO:0035684=GO_REF:0000024, GO:0019221=PMID:12207323, GO:0090265=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0030968=Reactome:REACT_18356, GO:0006935=PMID:10623817, GO:0071356=GO_REF:0000024, GO:0031727=GO_REF:0000024, GO:0043025=GO_REF:0000019, GO:0009887=PMID:9364936, GO:0007179=GO_REF:0000019, GO:0010332=GO_REF:0000019, GO:0046677=GO_REF:0000019, GO:0008009=GO_REF:0000019, GO:0070098=GO_REF:0000019, GO:2000427=GO_REF:0000024, GO:0007568=GO_REF:0000019, GO:0030593=GO_REF:0000019, GO:0033552=GO_REF:0000019, GO:0060137=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0071346=GO_REF:0000024, GO:0007186=PMID:10542238, GO:0007187=PMID:10770925, GO:0050870=GO_REF:0000024, GO:0050806=GO_REF:0000019, GO:0071347=GO_REF:0000024, GO:0010759=GO_REF:0000019, GO:0032570=GO_REF:0000019, GO:0048247=GO_REF:0000019, GO:0048246=PMID:12207323, GO:0006987=Reactome:REACT_18277, GO:0044267=Reactome:REACT_17015, GO:0045471=GO_REF:0000019, GO:0031100=GO_REF:0000019, GO:0019079=PMID:10985244, GO:0009617=PMID:16034137, GO:0005737=GO_REF:0000019, GO:0006955=GO_REF:0000002, GO:0006959=PMID:9548499, GO:0007010=PMID:10072545, GO:0007155=PMID:10198043, GO:0008201=GO_REF:0000019, GO:0043200=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0048010=GO_REF:0000019, GO:0014823=GO_REF:0000019, GO:0019725=PMID:18334747, GO:0043066=PMID:12753088, GO:0042493=GO_REF:0000019, GO:0005102=PMID:10542238, GO:0006874=GO_REF:0000019, GO:0005576=PMID:20041150, GO:0001525=PMID:18334747, GO:0007259=PMID:9670957, GO:0043615=PMID:12271471, GO:0010574=GO_REF:0000019, GO:0002548=PMID:12207323, GO:0009612=GO_REF:0000019, GO:2000502=PMID:7545673, GO:0007165=PMID:10770925, GO:0071222=GO_REF:0000024, GO:0004672=PMID:9973507, GO:0001938=GO_REF:0000019, GO:0016525=GO_REF:0000019, GO:0006468=PMID:9670957, GO:0051770=GO_REF:0000024, GO:0007166=PMID:9548499} P13500 C-C motif chemokine 2 protein 20110225 {GO:0009408=IEA, GO:0035684=ISS, GO:0019221=IDA, GO:0090265=IEA, GO:0005615=IEA, GO:0030968=TAS, GO:0006935=TAS, GO:0071356=ISS, GO:0031727=ISS, GO:0043025=IEA, GO:0009887=TAS, GO:0007179=IEA, GO:0010332=IEA, GO:0046677=IEA, GO:0008009=IEA, GO:0070098=IEA, GO:2000427=ISS, GO:0007568=IEA, GO:0030593=IEA, GO:0033552=IEA, GO:0060137=IEA, GO:0051384=IEA, GO:0071346=ISS, GO:0007186=TAS, GO:0007187=TAS, GO:0050870=ISS, GO:0050806=IEA, GO:0071347=ISS, GO:0010759=IEA, GO:0032570=IEA, GO:0048247=IEA, GO:0048246=IDA, GO:0006987=TAS, GO:0044267=TAS, GO:0045471=IEA, GO:0031100=IEA, GO:0019079=TAS, GO:0009617=IEP, GO:0005737=IEA, GO:0006955=IEA, GO:0006959=TAS, GO:0007010=IDA, GO:0007155=TAS, GO:0008201=IEA, GO:0043200=IEA, GO:0001666=IEA, GO:0048010=IEA, GO:0014823=IEA, GO:0019725=TAS, GO:0043066=IDA, GO:0042493=IEA, GO:0005102=TAS, GO:0006874=IEA, GO:0005576=IDA, GO:0001525=TAS, GO:0007259=TAS, GO:0043615=IDA, GO:0010574=IEA, GO:0002548=IDA, GO:0009612=IEA, GO:2000502=IDA, GO:0007165=NAS, GO:0071222=ISS, GO:0004672=TAS, GO:0001938=IEA, GO:0016525=IEA, GO:0006468=TAS, GO:0051770=ISS, GO:0007166=TAS} G-protein coupled receptor signaling pathway, G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, JAK-STAT cascade, activation of signaling protein activity involved in unfolded protein response, aging, angiogenesis, astrocyte cell migration, cell adhesion, cell surface receptor signaling pathway, cellular calcium ion homeostasis, cellular homeostasis, cellular protein metabolic process, cellular response to interferon-gamma, cellular response to interleukin-1, cellular response to lipopolysaccharide, cellular response to tumor necrosis factor, chemokine-mediated signaling pathway, chemotaxis, cytokine-mediated signaling pathway, cytoskeleton organization, endoplasmic reticulum unfolded protein response, helper T cell extravasation, humoral immune response, immune response, lymphocyte chemotaxis, macrophage chemotaxis, maternal process involved in parturition, monocyte chemotaxis, negative regulation of angiogenesis, negative regulation of apoptotic process, negative regulation of natural killer cell chemotaxis, neutrophil chemotaxis, organ morphogenesis, organ regeneration, positive regulation of T cell activation, positive regulation of apoptotic cell clearance, positive regulation of endothelial cell proliferation, positive regulation of immune complex clearance by monocytes and macrophages, positive regulation of macrophage chemotaxis, positive regulation of nitric-oxide synthase biosynthetic process, positive regulation of synaptic transmission, protein phosphorylation, regulation of vascular endothelial growth factor production, response to activity, response to amino acid stimulus, response to antibiotic, response to bacterium, response to drug, response to ethanol, response to gamma radiation, response to glucocorticoid stimulus, response to heat, response to hypoxia, response to mechanical stimulus, response to progesterone stimulus, response to vitamin B3, signal transduction, transforming growth factor beta receptor signaling pathway, vascular endothelial growth factor receptor signaling pathway, viral genome replication cytoplasm, extracellular region, extracellular space, neuronal cell body CCR2 chemokine receptor binding, chemokine activity, heparin binding, protein kinase activity, receptor binding Human UniProtKB:P10148 CCL20 Reactome UniProtKB {GO:0007165=PMID:9038201, GO:0008009=GO_REF:0000019, GO:0006955=GO_REF:0000002, GO:0006954=GO_REF:0000037, GO:0006935=GO_REF:0000037, GO:0007267=PMID:9038201, GO:0042466=GO_REF:0000019, GO:0005576=Reactome:REACT_22289, GO:0005615=GO_REF:0000037, GO:0042742=GO_REF:0000037} P78556 C-C motif chemokine 20 protein 20100217 {GO:0007165=TAS, GO:0008009=IEA, GO:0006955=IEA, GO:0006954=IEA, GO:0006935=IEA, GO:0007267=TAS, GO:0042466=IEA, GO:0005576=TAS, GO:0005615=IEA, GO:0042742=IEA} cell-cell signaling, chemokinesis, chemotaxis, defense response to bacterium, immune response, inflammatory response, signal transduction extracellular region, extracellular space chemokine activity Human CCL21 InterPro UniProtKB {GO:0051897=PMID:15778365, GO:0031295=GO_REF:0000024, GO:0007267=PMID:9235955, GO:0046330=PMID:15778365, GO:0051491=PMID:15569314, GO:0005615=GO_REF:0000037, GO:0097026=GO_REF:0000024, GO:2000147=PMID:15778365, GO:0031529=PMID:15569314, GO:0006955=GO_REF:0000002, GO:0006954=PMID:14592837, GO:0050921=GO_REF:0000024, GO:0034695=PMID:14592837, GO:0030838=PMID:11242036, GO:0043552=PMID:15778365, GO:0045860=PMID:15059845, GO:0031274=PMID:11242036, GO:0048469=GO_REF:0000024, GO:0070374=PMID:12729902, GO:0043123=PMID:15059845, GO:0001771=GO_REF:0000024, GO:0008009=GO_REF:0000002, GO:0051209=PMID:14592837, GO:2000529=PMID:14592837, GO:2000548=GO_REF:0000024, GO:0002407=PMID:15778365, GO:0033630=PMID:15569314, GO:0005576=GO_REF:0000002, GO:0032862=PMID:15778365, GO:0002606=GO_REF:0000024, GO:0010560=GO_REF:0000024, GO:2000107=PMID:15059845, GO:0048260=GO_REF:0000024, GO:0090023=PMID:21051556, GO:0001768=PMID:12729902, GO:0035759=PMID:15569314, GO:0001954=PMID:15569314, GO:0031732=GO_REF:0000024} Q5VZ73 C-C motif chemokine 21 protein 20130413 {GO:0051897=IDA, GO:0031295=ISS, GO:0007267=TAS, GO:0046330=IDA, GO:0051491=IDA, GO:0005615=IEA, GO:0097026=ISS, GO:2000147=IDA, GO:0031529=IDA, GO:0006955=IEA, GO:0006954=NAS, GO:0050921=ISS, GO:0034695=IDA, GO:0030838=IDA, GO:0043552=IDA, GO:0045860=IDA, GO:0031274=IDA, GO:0048469=ISS, GO:0070374=IDA, GO:0043123=IDA, GO:0001771=ISS, GO:0008009=IEA, GO:0051209=IDA, GO:2000529=IDA, GO:2000548=ISS, GO:0002407=IDA, GO:0033630=IDA, GO:0005576=IEA, GO:0032862=IDA, GO:0002606=ISS, GO:0010560=ISS, GO:2000107=IDA, GO:0048260=ISS, GO:0090023=IDA, GO:0001768=IDA, GO:0035759=IDA, GO:0001954=IDA, GO:0031732=ISS} T cell costimulation, activation of Rho GTPase activity, cell maturation, cell-cell signaling, dendritic cell chemotaxis, dendritic cell dendrite assembly, establishment of T cell polarity, immune response, immunological synapse formation, inflammatory response, mesangial cell-matrix adhesion, negative regulation of dendritic cell dendrite assembly, negative regulation of leukocyte apoptotic process, positive regulation of ERK1 and ERK2 cascade, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of JNK cascade, positive regulation of actin filament polymerization, positive regulation of cell adhesion mediated by integrin, positive regulation of cell motility, positive regulation of cell-matrix adhesion, positive regulation of chemotaxis, positive regulation of dendritic cell antigen processing and presentation, positive regulation of filopodium assembly, positive regulation of glycoprotein biosynthetic process, positive regulation of myeloid dendritic cell chemotaxis, positive regulation of neutrophil chemotaxis, positive regulation of phosphatidylinositol 3-kinase activity, positive regulation of protein kinase B signaling cascade, positive regulation of protein kinase activity, positive regulation of pseudopodium assembly, positive regulation of receptor-mediated endocytosis, release of sequestered calcium ion into cytosol, response to prostaglandin E stimulus, ruffle organization extracellular region, extracellular space CCR7 chemokine receptor binding, chemokine activity Human InterPro:IPR001811 CCL22 Reactome UniProtKB {GO:0007165=PMID:9743322, GO:0008009=GO_REF:0000002, GO:0006955=GO_REF:0000002, GO:0006954=PMID:9151897, GO:0006935=GO_REF:0000037, GO:0007267=PMID:9151897, GO:0005576=Reactome:REACT_21265, GO:0009615=PMID:9381181, GO:0005615=GO_REF:0000037} O00626 C-C motif chemokine 22 protein 20091020 {GO:0007165=TAS, GO:0008009=IEA, GO:0006955=IEA, GO:0006954=TAS, GO:0006935=IEA, GO:0007267=TAS, GO:0005576=TAS, GO:0009615=TAS, GO:0005615=IEA} cell-cell signaling, chemotaxis, immune response, inflammatory response, response to virus, signal transduction extracellular region, extracellular space chemokine activity Human CCL23 Reactome UniProtKB {GO:0008009=PMID:10660125, GO:0008285=PMID:9104803, GO:0006874=PMID:9886417, GO:0007267=PMID:9104803, GO:0005576=Reactome:REACT_22436, GO:0005615=GO_REF:0000037, GO:0002548=PMID:10660125, GO:0007165=PMID:9886417, GO:0006955=GO_REF:0000002, GO:0006954=GO_REF:0000037, GO:0006935=PMID:9104803, GO:0007186=PMID:9886417, GO:2001264=PMID:10660125, GO:0008201=GO_REF:0000037} P55773 C-C motif chemokine 23 protein 20091023 {GO:0008009=IDA, GO:0008285=TAS, GO:0006874=TAS, GO:0007267=TAS, GO:0005576=TAS, GO:0005615=IEA, GO:0002548=IC, GO:0007165=NAS, GO:0006955=IEA, GO:0006954=IEA, GO:0006935=TAS, GO:0007186=TAS, GO:2001264=IDA, GO:0008201=IEA} G-protein coupled receptor signaling pathway, cell-cell signaling, cellular calcium ion homeostasis, chemotaxis, immune response, inflammatory response, monocyte chemotaxis, negative regulation of C-C chemokine binding, negative regulation of cell proliferation, signal transduction extracellular region, extracellular space chemokine activity, heparin binding Human CCL24 BHF-UCL UniProtKB {GO:0008009=PMID:10072545, GO:0030335=PMID:19525930, GO:0008360=PMID:10072545, GO:0007267=PMID:9104803, GO:0032855=PMID:19525930, GO:0005615=GO_REF:0000037, GO:0045766=GO_REF:0000019, GO:0007165=PMID:9104803, GO:0006955=GO_REF:0000002, GO:0006954=GO_REF:0000037, GO:0030838=PMID:19525930, GO:0006935=PMID:9104803, GO:0001938=PMID:19525930, GO:0050729=GO_REF:0000019, GO:0007010=PMID:10072545, GO:0048245=PMID:10072545} O00175 C-C motif chemokine 24 protein 20091106 {GO:0008009=IDA, GO:0030335=IDA, GO:0008360=IDA, GO:0007267=TAS, GO:0032855=IDA, GO:0005615=IEA, GO:0045766=IEA, GO:0007165=TAS, GO:0006955=IEA, GO:0006954=IEA, GO:0030838=IDA, GO:0006935=TAS, GO:0001938=IDA, GO:0050729=IEA, GO:0007010=IDA, GO:0048245=IDA} cell-cell signaling, chemotaxis, cytoskeleton organization, eosinophil chemotaxis, immune response, inflammatory response, positive regulation of Rac GTPase activity, positive regulation of actin filament polymerization, positive regulation of angiogenesis, positive regulation of cell migration, positive regulation of endothelial cell proliferation, positive regulation of inflammatory response, regulation of cell shape, signal transduction extracellular space chemokine activity Human CCL25 BHF-UCL UniProtKB {GO:0031735=PMID:10706668, GO:0008009=GO_REF:0000019, GO:0006955=GO_REF:0000002, GO:0006954=GO_REF:0000037, GO:0007186=PMID:10544196, GO:0005179=PMID:9285413, GO:0006935=GO_REF:0000019, GO:0005576=Reactome:REACT_22289, GO:0050900=GO_REF:0000019, GO:0005615=GO_REF:0000037, GO:0007166=PMID:10640743} O15444 C-C motif chemokine 25 protein 20110329 {GO:0031735=IDA, GO:0008009=IEA, GO:0006955=IEA, GO:0006954=IEA, GO:0007186=TAS, GO:0005179=TAS, GO:0006935=IEA, GO:0005576=TAS, GO:0050900=IEA, GO:0005615=IEA, GO:0007166=TAS} G-protein coupled receptor signaling pathway, cell surface receptor signaling pathway, chemotaxis, immune response, inflammatory response, leukocyte migration extracellular region, extracellular space CCR10 chemokine receptor binding, chemokine activity, hormone activity Human CCL26 BHF-UCL UniProtKB {GO:0007165=PMID:10373330, GO:0008009=GO_REF:0000002, GO:0006955=GO_REF:0000002, GO:0030335=PMID:19525930, GO:0006954=GO_REF:0000037, GO:0030838=PMID:19525930, GO:0001938=PMID:19525930, GO:0006935=GO_REF:0000037, GO:0007267=PMID:10373330, GO:0032855=PMID:19525930, GO:0005615=GO_REF:0000037} Q9Y258 C-C motif chemokine 26 protein 20091106 {GO:0007165=NAS, GO:0008009=IEA, GO:0006955=IEA, GO:0030335=IDA, GO:0006954=IEA, GO:0030838=IDA, GO:0001938=IDA, GO:0006935=IEA, GO:0007267=TAS, GO:0032855=IDA, GO:0005615=IEA} cell-cell signaling, chemotaxis, immune response, inflammatory response, positive regulation of Rac GTPase activity, positive regulation of actin filament polymerization, positive regulation of cell migration, positive regulation of endothelial cell proliferation, signal transduction extracellular space chemokine activity Human CCL27 Reactome UniProtKB {GO:0008009=GO_REF:0000002, GO:0006955=GO_REF:0000002, GO:0006935=PMID:10588729, GO:0007267=PMID:10588729, GO:0005576=Reactome:REACT_22289, GO:0005615=GO_REF:0000037} Q9Y4X3 C-C motif chemokine 27 protein 20080717 {GO:0008009=IEA, GO:0006955=IEA, GO:0006935=TAS, GO:0007267=TAS, GO:0005576=TAS, GO:0005615=IEA} cell-cell signaling, chemotaxis, immune response extracellular region, extracellular space chemokine activity Human CCL28 Reactome UniProtKB {GO:0008009=PMID:10781587, GO:0006955=GO_REF:0000002, GO:0006935=PMID:10781587, GO:0005576=Reactome:REACT_22289, GO:0005615=GO_REF:0000037, GO:0007204=GO_REF:0000019} Q9NRJ3 C-C motif chemokine 28 protein 20080717 {GO:0008009=TAS, GO:0006955=IEA, GO:0006935=TAS, GO:0005576=TAS, GO:0005615=IEA, GO:0007204=IEA} chemotaxis, elevation of cytosolic calcium ion concentration, immune response extracellular region, extracellular space chemokine activity Human CCL3 GOC UniProtKB {GO:0005515=PMID:21784977, GO:0019722=PMID:10072545, GO:0051928=PMID:15764707, GO:0007267=PMID:10679098, GO:0006887=PMID:10734056, GO:0005615=PMID:20167378, GO:0010818=PMID:10706735, GO:0005829=PMID:19523456, GO:0050850=PMID:10679098, GO:0005622=PMID:10072545, GO:0031726=PMID:15764707, GO:0005737=PMID:21784977, GO:0043525=GO_REF:0000024, GO:0006954=PMID:10706735, GO:0006935=PMID:10679098, GO:0050718=GO_REF:0000024, GO:0007010=PMID:10072545, GO:0007610=PMID:20167378, GO:0006816=PMID:10734056, GO:0008009=PMID:10660125, GO:0030335=PMID:10706735, GO:0032760=GO_REF:0000024, GO:0023052=PMID:12032188, GO:0030593=PMID:10706735, GO:0006874=PMID:10072545, GO:0009636=PMID:10841574, GO:0071621=PMID:10706735, GO:0005576=PMID:20041150, GO:0014808=PMID:19523456, GO:0045671=PMID:21403648, GO:0042056=PMID:10660125, GO:0043308=PMID:10706735, GO:0043615=GO_REF:0000024, GO:0001649=PMID:21403648, GO:0050918=PMID:15001559, GO:0002548=PMID:10660125, GO:0016310=PMID:21403648, GO:0016004=PMID:10734056, GO:0050729=GO_REF:0000024, GO:0048245=PMID:10072545, GO:0070723=PMID:19523456, GO:0006468=PMID:10734056, GO:0004698=PMID:15764707, GO:0048247=PMID:10706735, GO:0048246=GO_REF:0000024, GO:0031730=PMID:8699119, GO:0051930=PMID:15764707, GO:2000503=PMID:7545673} P10147 C-C motif chemokine 3 protein 20130413 {GO:0005515=IPI, GO:0019722=IDA, GO:0051928=IDA, GO:0007267=IDA, GO:0006887=IDA, GO:0005615=IDA, GO:0010818=IDA, GO:0005829=IDA, GO:0050850=IMP, GO:0005622=IDA, GO:0031726=IPI, GO:0005737=IDA, GO:0043525=ISS, GO:0006954=IDA, GO:0006935=IDA, GO:0050718=ISS, GO:0007010=IDA, GO:0007610=IDA, GO:0006816=IDA, GO:0008009=IDA, GO:0030335=IDA, GO:0032760=ISS, GO:0023052=IEP, GO:0030593=IDA, GO:0006874=IDA, GO:0009636=IDA, GO:0071621=IDA, GO:0005576=IDA, GO:0014808=IDA, GO:0045671=IDA, GO:0042056=IDA, GO:0043308=IDA, GO:0043615=ISS, GO:0001649=IEP, GO:0050918=IDA, GO:0002548=IC, GO:0016310=IDA, GO:0016004=IDA, GO:0050729=ISS, GO:0048245=IDA, GO:0070723=IDA, GO:0006468=IDA, GO:0004698=IDA, GO:0048247=IDA, GO:0048246=ISS, GO:0031730=IPI, GO:0051930=IDA, GO:2000503=IDA} T cell chemotaxis, astrocyte cell migration, behavior, calcium ion transport, calcium-mediated signaling, cell-cell signaling, cellular calcium ion homeostasis, chemotaxis, cytoskeleton organization, eosinophil chemotaxis, eosinophil degranulation, exocytosis, granulocyte chemotaxis, inflammatory response, lymphocyte chemotaxis, macrophage chemotaxis, monocyte chemotaxis, negative regulation of osteoclast differentiation, neutrophil chemotaxis, osteoblast differentiation, phosphorylation, positive chemotaxis, positive regulation of calcium ion transport, positive regulation of calcium-mediated signaling, positive regulation of cell migration, positive regulation of inflammatory response, positive regulation of interleukin-1 beta secretion, positive regulation of natural killer cell chemotaxis, positive regulation of neuron apoptotic process, positive regulation of tumor necrosis factor production, protein phosphorylation, regulation of sensory perception of pain, release of sequestered calcium ion into cytosol by sarcoplasmic reticulum, response to cholesterol, response to toxic substance, signaling cytoplasm, cytosol, extracellular region, extracellular space, intracellular CCR1 chemokine receptor binding, CCR5 chemokine receptor binding, calcium-dependent protein kinase C activity, chemoattractant activity, chemokine activity, phospholipase activator activity, protein binding Human CCL3L1 Reactome UniProtKB {GO:0008009=GO_REF:0000029, GO:0006955=GO_REF:0000002, GO:0006954=PMID:1694014, GO:0008285=PMID:2271120, GO:0006935=GO_REF:0000029, GO:0005576=Reactome:REACT_21265, GO:0005615=GO_REF:0000037} P16619 C-C motif chemokine 3-like 1 protein 20091020 {GO:0008009=NAS, GO:0006955=IEA, GO:0006954=TAS, GO:0008285=TAS, GO:0006935=NAS, GO:0005576=TAS, GO:0005615=IEA} chemotaxis, immune response, inflammatory response, negative regulation of cell proliferation extracellular region, extracellular space chemokine activity Human CCL3L3 null null {} null null null null {} null null null CCL4 Reactome UniProtKB {GO:0008009=GO_REF:0000002, GO:0051928=PMID:8699119, GO:0007267=PMID:2521882, GO:0009636=PMID:10841574, GO:0006928=PMID:9759849, GO:0005576=Reactome:REACT_21265, GO:0009615=PMID:9743377, GO:0005615=GO_REF:0000037, GO:0005125=PMID:2462251, GO:0050850=PMID:10679098, GO:0031726=PMID:7545673, GO:0007165=PMID:9558100, GO:0006955=GO_REF:0000002, GO:0007163=PMID:9759849, GO:0006954=GO_REF:0000037, GO:0006935=GO_REF:0000037, GO:0007155=PMID:10929056, GO:0031730=PMID:10679098, GO:2000503=PMID:7545673} P13236 C-C motif chemokine 4 protein 20091020 {GO:0008009=IEA, GO:0051928=IDA, GO:0007267=TAS, GO:0009636=IDA, GO:0006928=TAS, GO:0005576=TAS, GO:0009615=TAS, GO:0005615=IEA, GO:0005125=TAS, GO:0050850=IMP, GO:0031726=IPI, GO:0007165=TAS, GO:0006955=IEA, GO:0007163=TAS, GO:0006954=IEA, GO:0006935=IEA, GO:0007155=TAS, GO:0031730=IPI, GO:2000503=IDA} cell adhesion, cell-cell signaling, cellular component movement, chemotaxis, establishment or maintenance of cell polarity, immune response, inflammatory response, positive regulation of calcium ion transport, positive regulation of calcium-mediated signaling, positive regulation of natural killer cell chemotaxis, response to toxic substance, response to virus, signal transduction extracellular region, extracellular space CCR1 chemokine receptor binding, CCR5 chemokine receptor binding, chemokine activity, cytokine activity Human CCL5 GOC UniProtKB {GO:0005515=PMID:8699119, GO:0051928=PMID:8699119, GO:0070233=PMID:10488085, GO:0070234=PMID:10488085, GO:0043621=PMID:10488085, GO:0006887=PMID:10734056, GO:0005615=GO_REF:0000037, GO:0043623=PMID:18337562, GO:0042803=PMID:10488085, GO:0031726=PMID:10910894, GO:0030298=PMID:10488085, GO:0006935=PMID:1380064, GO:0070100=PMID:8631850, GO:0031729=PMID:9417081, GO:0045070=PMID:10488085, GO:0045071=PMID:10490959, GO:0031584=PMID:9469451, GO:0008009=PMID:1699135, GO:0070098=PMID:18337562, GO:0042531=PMID:9417081, GO:0045744=PMID:10734056, GO:0030335=PMID:7545673, GO:0009636=PMID:10841574, GO:0014068=PMID:7544376, GO:0042056=PMID:15001559, GO:0045785=PMID:10910894, GO:0016004=PMID:10734056, GO:0045089=PMID:21148810, GO:0048245=PMID:16778803, GO:0010759=PMID:16778803, GO:0048246=PMID:18337562, GO:0090026=PMID:19779041, GO:0042119=PMID:10488085, GO:0031730=PMID:9139699, GO:0007267=PMID:8558019, GO:0014911=PMID:21297082, GO:0006955=GO_REF:0000002, GO:0005737=GO_REF:0000019, GO:0002676=PMID:10488085, GO:0042102=PMID:18832695, GO:0007159=PMID:8558019, GO:0045948=PMID:18337562, GO:0006816=PMID:10734056, GO:0010535=PMID:11278738, GO:0050863=PMID:10488085, GO:0051262=PMID:10488085, GO:0010820=PMID:7544376, GO:0002407=PMID:18337562, GO:0006874=PMID:10734056, GO:0005576=Reactome:REACT_22289, GO:0042379=PMID:7517217, GO:0034112=PMID:10488085, GO:0033634=PMID:8558019, GO:2000110=GO_REF:0000019, GO:0009615=PMID:10488085, GO:0048661=PMID:21297082, GO:0050918=PMID:15001559, GO:0046427=PMID:11278738, GO:0002548=PMID:10660125, GO:0046817=PMID:8631850, GO:0004435=PMID:10734056, GO:0006468=PMID:10734056, GO:0031328=PMID:18337562, GO:0042327=PMID:18337562, GO:2000503=PMID:7545673} P13501 C-C motif chemokine 5 protein 20130413 {GO:0005515=IPI, GO:0051928=IDA, GO:0070233=IDA, GO:0070234=IDA, GO:0043621=IDA, GO:0006887=IDA, GO:0005615=IEA, GO:0043623=IDA, GO:0042803=IDA, GO:0031726=IDA, GO:0030298=IDA, GO:0006935=NAS, GO:0070100=IDA, GO:0031729=TAS, GO:0045070=TAS, GO:0045071=IDA, GO:0031584=IDA, GO:0008009=IDA, GO:0070098=TAS, GO:0042531=IDA, GO:0045744=IDA, GO:0030335=IDA, GO:0009636=IDA, GO:0014068=IDA, GO:0042056=IDA, GO:0045785=IDA, GO:0016004=IDA, GO:0045089=TAS, GO:0048245=IDA, GO:0010759=IDA, GO:0048246=TAS, GO:0090026=IDA, GO:0042119=IDA, GO:0031730=IPI, GO:0007267=IDA, GO:0014911=IDA, GO:0006955=IEA, GO:0005737=IEA, GO:0002676=TAS, GO:0042102=IDA, GO:0007159=IDA, GO:0045948=NAS, GO:0006816=IDA, GO:0010535=TAS, GO:0050863=IDA, GO:0051262=IDA, GO:0010820=IDA, GO:0002407=TAS, GO:0006874=IDA, GO:0005576=TAS, GO:0042379=IPI, GO:0034112=IDA, GO:0033634=IDA, GO:2000110=IEA, GO:0009615=TAS, GO:0048661=IDA, GO:0050918=IDA, GO:0046427=TAS, GO:0002548=IC, GO:0046817=IDA, GO:0004435=IDA, GO:0006468=IDA, GO:0031328=IDA, GO:0042327=IDA, GO:2000503=IDA} activation of phospholipase D activity, calcium ion transport, cell-cell signaling, cellular calcium ion homeostasis, cellular protein complex assembly, chemokine-mediated signaling pathway, chemotaxis, dendritic cell chemotaxis, eosinophil chemotaxis, exocytosis, immune response, leukocyte cell-cell adhesion, macrophage chemotaxis, monocyte chemotaxis, negative regulation of G-protein coupled receptor protein signaling pathway, negative regulation of T cell apoptotic process, negative regulation of chemokine-mediated signaling pathway, negative regulation of macrophage apoptotic process, negative regulation of viral genome replication, neutrophil activation, positive chemotaxis, positive regulation of JAK-STAT cascade, positive regulation of T cell apoptotic process, positive regulation of T cell chemotaxis, positive regulation of T cell proliferation, positive regulation of activation of JAK2 kinase activity, positive regulation of calcium ion transport, positive regulation of cell adhesion, positive regulation of cell migration, positive regulation of cell-cell adhesion mediated by integrin, positive regulation of cellular biosynthetic process, positive regulation of homotypic cell-cell adhesion, positive regulation of innate immune response, positive regulation of macrophage chemotaxis, positive regulation of monocyte chemotaxis, positive regulation of natural killer cell chemotaxis, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of phosphorylation, positive regulation of smooth muscle cell migration, positive regulation of smooth muscle cell proliferation, positive regulation of translational initiation, positive regulation of tyrosine phosphorylation of STAT protein, positive regulation of viral genome replication, protein phosphorylation, protein tetramerization, regulation of T cell activation, regulation of chronic inflammatory response, response to toxic substance, response to virus cytoplasm, extracellular region, extracellular space CCR1 chemokine receptor binding, CCR4 chemokine receptor binding, CCR5 chemokine receptor binding, chemoattractant activity, chemokine activity, chemokine receptor antagonist activity, chemokine receptor binding, phosphatidylinositol phospholipase C activity, phospholipase activator activity, protein binding, protein homodimerization activity, protein self-association, receptor signaling protein tyrosine kinase activator activity Human CCL7 Reactome UniProtKB {GO:0008009=PMID:10072545, GO:0030335=PMID:7545673, GO:0007267=PMID:7916328, GO:0006874=PMID:10770925, GO:0005576=Reactome:REACT_21265, GO:0005615=GO_REF:0000037, GO:0002548=PMID:10660125, GO:0031726=PMID:7545673, GO:0007165=PMID:10770925, GO:0006955=GO_REF:0000002, GO:0071361=GO_REF:0000019, GO:0006954=GO_REF:0000037, GO:0006935=PMID:9780207, GO:0031727=GO_REF:0000019, GO:0007010=PMID:10072545, GO:0048245=PMID:10072545, GO:0008201=GO_REF:0000037, GO:0010332=GO_REF:0000019, GO:2000503=PMID:7545673} P80098 C-C motif chemokine 7 protein 20091020 {GO:0008009=IDA, GO:0030335=IDA, GO:0007267=TAS, GO:0006874=TAS, GO:0005576=TAS, GO:0005615=IEA, GO:0002548=IC, GO:0031726=IPI, GO:0007165=TAS, GO:0006955=IEA, GO:0071361=IEA, GO:0006954=IEA, GO:0006935=TAS, GO:0031727=IEA, GO:0007010=IDA, GO:0048245=IDA, GO:0008201=IEA, GO:0010332=IEA, GO:2000503=IDA} cell-cell signaling, cellular calcium ion homeostasis, cellular response to ethanol, chemotaxis, cytoskeleton organization, eosinophil chemotaxis, immune response, inflammatory response, monocyte chemotaxis, positive regulation of cell migration, positive regulation of natural killer cell chemotaxis, response to gamma radiation, signal transduction extracellular region, extracellular space CCR1 chemokine receptor binding, CCR2 chemokine receptor binding, chemokine activity, heparin binding Human CCL8 GOC UniProtKB {GO:0008009=GO_REF:0000002, GO:0006874=PMID:10734056, GO:0007267=PMID:10734056, GO:0006887=PMID:10734056, GO:0009615=PMID:9468473, GO:0005615=GO_REF:0000037, GO:0007165=PMID:9119400, GO:0006955=GO_REF:0000002, GO:0006954=GO_REF:0000037, GO:0016004=PMID:10734056, GO:0006935=GO_REF:0000037, GO:0006468=PMID:10734056, GO:0006816=PMID:10734056, GO:0008201=GO_REF:0000037} P80075 C-C motif chemokine 8 protein 20130413 {GO:0008009=IEA, GO:0006874=IDA, GO:0007267=IDA, GO:0006887=IDA, GO:0009615=TAS, GO:0005615=IEA, GO:0007165=TAS, GO:0006955=IEA, GO:0006954=IEA, GO:0016004=IDA, GO:0006935=IEA, GO:0006468=IDA, GO:0006816=IDA, GO:0008201=IEA} calcium ion transport, cell-cell signaling, cellular calcium ion homeostasis, chemotaxis, exocytosis, immune response, inflammatory response, protein phosphorylation, response to virus, signal transduction extracellular space chemokine activity, heparin binding, phospholipase activator activity Human CCM2 IntAct UniProtKB {GO:0005515=PMID:17657516, GO:0005737=PMID:16037064, GO:0061154=PMID:19151727, GO:0007229=PMID:16037064, GO:0051403=PMID:16037064, GO:0001570=PMID:14740320} Q9BSQ5 Malcavernin protein 20130415 {GO:0005515=IPI, GO:0005737=IDA, GO:0061154=IMP, GO:0007229=TAS, GO:0051403=TAS, GO:0001570=IMP} endothelial tube morphogenesis, integrin-mediated signaling pathway, stress-activated MAPK cascade, vasculogenesis cytoplasm protein binding Human UniProtKB:Q9BUL8 CCNA1 IntAct UniProtKB {GO:0005515=PMID:15232106, GO:0019901=GO_REF:0000002, GO:0000079=GO_REF:0000002, GO:0007283=PMID:9843212, GO:0005829=PMID:9041194, GO:0007067=GO_REF:0000037, GO:0000082=Reactome:REACT_1783, GO:0000083=Reactome:REACT_683, GO:0000086=Reactome:REACT_2203, GO:0015630=GO_REF:0000054, GO:0005654=Reactome:REACT_22145, GO:0000278=Reactome:REACT_152, GO:0007141=PMID:9843212, GO:0051301=GO_REF:0000037} P78396 Cyclin-A1 protein 20130415 {GO:0005515=IPI, GO:0019901=IEA, GO:0000079=IEA, GO:0007283=TAS, GO:0005829=TAS, GO:0007067=IEA, GO:0000082=TAS, GO:0000083=TAS, GO:0000086=TAS, GO:0015630=IDA, GO:0005654=TAS, GO:0000278=TAS, GO:0007141=TAS, GO:0051301=IEA} G1/S transition of mitotic cell cycle, G2/M transition of mitotic cell cycle, cell division, male meiosis I, mitosis, mitotic cell cycle, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of transcription involved in G1/S phase of mitotic cell cycle, spermatogenesis cytosol, microtubule cytoskeleton, nucleoplasm protein binding, protein kinase binding Human UniProtKB:P38936 CCNA2 BHF-UCL UniProtKB {GO:0005515=PMID:23455922, GO:0007095=PMID:1312467, GO:0019901=GO_REF:0000019, GO:0007265=PMID:9054499, GO:0005634=PMID:16109376, GO:0000079=GO_REF:0000002, GO:0007067=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0001939=GO_REF:0000019, GO:0000086=Reactome:REACT_2203, GO:0005654=Reactome:REACT_1627, GO:0001940=GO_REF:0000019, GO:0045893=GO_REF:0000019, GO:0000278=Reactome:REACT_152, GO:0051301=GO_REF:0000037} P20248 Cyclin-A2 protein 20091126 {GO:0005515=IPI, GO:0007095=TAS, GO:0019901=IEA, GO:0007265=IEP, GO:0005634=IDA, GO:0000079=IEA, GO:0007067=IEA, GO:0005737=IEA, GO:0001939=IEA, GO:0000086=TAS, GO:0005654=TAS, GO:0001940=IEA, GO:0045893=IEA, GO:0000278=TAS, GO:0051301=IEA} G2/M transition of mitotic cell cycle, Ras protein signal transduction, cell division, mitosis, mitotic G2 DNA damage checkpoint, mitotic cell cycle, positive regulation of transcription, DNA-dependent, regulation of cyclin-dependent protein serine/threonine kinase activity cytoplasm, female pronucleus, male pronucleus, nucleoplasm, nucleus protein binding, protein kinase binding Human CCNB1 UniProtKB UniProtKB {GO:0060045=GO_REF:0000019, GO:0007077=Reactome:REACT_160255, GO:0005515=PMID:21952639, GO:0000236=PMID:18195732, GO:0046680=GO_REF:0000019, GO:0001556=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0005113=PMID:11331587, GO:0071398=GO_REF:0000019, GO:0016301=GO_REF:0000019, GO:0071283=GO_REF:0000019, GO:0005813=PMID:12524548, GO:0019901=GO_REF:0000002, GO:0001701=GO_REF:0000019, GO:0007049=GO_REF:0000038, GO:0000922=PMID:18195732, GO:0045931=PMID:18195732, GO:0055015=GO_REF:0000019, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_150132, GO:0007080=PMID:18195732, GO:0000278=Reactome:REACT_152, GO:0031442=GO_REF:0000019, GO:0051301=GO_REF:0000038, GO:0043148=PMID:18195732, GO:0005634=GO_REF:0000002, GO:0000079=GO_REF:0000002, GO:0042246=GO_REF:0000019, GO:0031145=Reactome:REACT_6828, GO:0005829=Reactome:REACT_160217, GO:0005737=PMID:11331587, GO:0000082=Reactome:REACT_1783, GO:0000088=Reactome:REACT_765, GO:0000086=Reactome:REACT_2203, GO:0000087=Reactome:REACT_910, GO:0071174=PMID:18195732, GO:0060623=GO_REF:0000019, GO:0051987=PMID:18195732, GO:0042493=GO_REF:0000019, GO:0051437=Reactome:REACT_6904, GO:0071456=GO_REF:0000019, GO:0048565=GO_REF:0000019, GO:0051439=Reactome:REACT_6837, GO:0009612=GO_REF:0000019, GO:0071407=GO_REF:0000019, GO:0033129=GO_REF:0000019, GO:0006461=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0000942=PMID:18195732, GO:0010629=GO_REF:0000019, GO:0001933=GO_REF:0000019, GO:0006468=GO_REF:0000019} Q5TZP9 Cyclin B1 protein 20130413 {GO:0060045=IEA, GO:0007077=TAS, GO:0005515=IPI, GO:0000236=IDA, GO:0046680=IEA, GO:0001556=IEA, GO:0007283=IEA, GO:0005113=IPI, GO:0071398=IEA, GO:0016301=IEA, GO:0071283=IEA, GO:0005813=IDA, GO:0019901=IEA, GO:0001701=IEA, GO:0007049=IEA, GO:0000922=IDA, GO:0045931=IMP, GO:0055015=IEA, GO:0000075=TAS, GO:0005654=TAS, GO:0007080=IMP, GO:0000278=TAS, GO:0031442=IEA, GO:0051301=IEA, GO:0043148=IMP, GO:0005634=IEA, GO:0000079=IEA, GO:0042246=IEA, GO:0031145=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0000082=TAS, GO:0000088=TAS, GO:0000086=TAS, GO:0000087=TAS, GO:0071174=IMP, GO:0060623=IEA, GO:0051987=IMP, GO:0042493=IEA, GO:0051437=TAS, GO:0071456=IEA, GO:0048565=IEA, GO:0051439=TAS, GO:0009612=IEA, GO:0071407=IEA, GO:0033129=IEA, GO:0006461=IEA, GO:0016020=IEA, GO:0000942=IDA, GO:0010629=IEA, GO:0001933=IEA, GO:0006468=IEA} G1/S transition of mitotic cell cycle, G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle, cell cycle checkpoint, cell division, cellular response to fatty acid, cellular response to hypoxia, cellular response to iron(III) ion, cellular response to organic cyclic compound, digestive tract development, in utero embryonic development, mitotic cell cycle, mitotic metaphase plate congression, mitotic nuclear envelope disassembly, mitotic prometaphase, mitotic prophase, mitotic spindle checkpoint, mitotic spindle stabilization, negative regulation of gene expression, negative regulation of protein phosphorylation, oocyte maturation, positive regulation of attachment of spindle microtubules to kinetochore, positive regulation of cardiac muscle cell proliferation, positive regulation of histone phosphorylation, positive regulation of mRNA 3'-end processing, positive regulation of mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein complex assembly, protein phosphorylation, regulation of chromosome condensation, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, response to DDT, response to drug, response to mechanical stimulus, spermatogenesis, tissue regeneration, ventricular cardiac muscle cell development centrosome, condensed nuclear chromosome outer kinetochore, cytoplasm, cytosol, membrane, nucleoplasm, nucleus, spindle pole kinase activity, patched binding, protein binding, protein kinase binding Human UniProtKB-KW:KW-0132 CCNB1IP1 IntAct UniProtKB {GO:0005515=PMID:12612082, GO:0016567=GO_REF:0000041, GO:0005694=GO_REF:0000039, GO:0051026=GO_REF:0000019, GO:0035265=GO_REF:0000019, GO:0016874=GO_REF:0000037, GO:0007286=GO_REF:0000019, GO:0001825=GO_REF:0000019, GO:0006915=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0046872=GO_REF:0000037, GO:0007132=GO_REF:0000019} Q9NPC3 E3 ubiquitin-protein ligase CCNB1IP1 protein 20130415 {GO:0005515=IPI, GO:0016567=IEA, GO:0005694=IEA, GO:0051026=IEA, GO:0035265=IEA, GO:0016874=IEA, GO:0007286=IEA, GO:0001825=IEA, GO:0006915=IEA, GO:0005634=IEA, GO:0046872=IEA, GO:0007132=IEA} apoptotic process, blastocyst formation, chiasma assembly, meiotic metaphase I, organ growth, protein ubiquitination, spermatid development chromosome, nucleus ligase activity, metal ion binding, protein binding Human UniProtKB:P62972 CCNB2 IntAct UniProtKB {GO:0005515=PMID:23455922, GO:0007077=Reactome:REACT_160255, GO:0000236=Reactome:REACT_682, GO:0005813=PMID:21399614, GO:0019901=GO_REF:0000002, GO:0005634=GO_REF:0000002, GO:0048538=GO_REF:0000019, GO:0000079=GO_REF:0000002, GO:0001701=GO_REF:0000019, GO:0005829=Reactome:REACT_160217, GO:0007049=GO_REF:0000038, GO:0000088=Reactome:REACT_765, GO:0016020=GO_REF:0000019, GO:0000086=Reactome:REACT_2203, GO:0015630=GO_REF:0000054, GO:0000087=Reactome:REACT_910, GO:0000075=Reactome:REACT_1538, GO:0000278=Reactome:REACT_152, GO:0043029=GO_REF:0000019, GO:0040007=GO_REF:0000019, GO:0051301=GO_REF:0000037} O95067 G2/mitotic-specific cyclin-B2 protein 20130415 {GO:0005515=IPI, GO:0007077=TAS, GO:0000236=TAS, GO:0005813=IDA, GO:0019901=IEA, GO:0005634=IEA, GO:0048538=IEA, GO:0000079=IEA, GO:0001701=IEA, GO:0005829=TAS, GO:0007049=IEA, GO:0000088=TAS, GO:0016020=IEA, GO:0000086=TAS, GO:0015630=IDA, GO:0000087=TAS, GO:0000075=TAS, GO:0000278=TAS, GO:0043029=IEA, GO:0040007=IEA, GO:0051301=IEA} G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, T cell homeostasis, cell cycle, cell cycle checkpoint, cell division, growth, in utero embryonic development, mitotic cell cycle, mitotic nuclear envelope disassembly, mitotic prometaphase, mitotic prophase, regulation of cyclin-dependent protein serine/threonine kinase activity, thymus development centrosome, cytosol, membrane, microtubule cytoskeleton, nucleus protein binding, protein kinase binding Human UniProtKB:P24941 CCNB3 HPA UniProtKB {GO:0005515=PMID:12185076, GO:0007126=GO_REF:0000037, GO:0019901=GO_REF:0000002, GO:0010389=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000079=GO_REF:0000002, GO:0051301=GO_REF:0000037} Q8WWL7 G2/mitotic-specific cyclin-B3 protein 20080205 {GO:0005515=IPI, GO:0007126=IEA, GO:0019901=IEA, GO:0010389=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0000079=IEA, GO:0051301=IEA} cell division, meiosis, regulation of G2/M transition of mitotic cell cycle, regulation of cyclin-dependent protein serine/threonine kinase activity nucleolus, nucleus protein binding, protein kinase binding NOT Human CCNC InterPro UniProtKB {GO:0005515=PMID:19914168, GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000002, GO:0006367=Reactome:REACT_12627, GO:0019901=GO_REF:0000002, GO:0000079=GO_REF:0000002, GO:0006351=Reactome:REACT_121061, GO:0007219=Reactome:REACT_118859, GO:0016592=GO_REF:0000019, GO:0045944=Reactome:REACT_120734, GO:0016591=GO_REF:0000002, GO:0005654=Reactome:REACT_160249, GO:0007179=Reactome:REACT_6844} Q5JV82 Cyclin-C protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0006355=IEA, GO:0006367=TAS, GO:0019901=IEA, GO:0000079=IEA, GO:0006351=TAS, GO:0007219=TAS, GO:0016592=IEA, GO:0045944=TAS, GO:0016591=IEA, GO:0005654=TAS, GO:0007179=TAS} Notch signaling pathway, gene expression, positive regulation of transcription from RNA polymerase II promoter, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of transcription, DNA-dependent, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway DNA-directed RNA polymerase II, holoenzyme, mediator complex, nucleoplasm protein binding, protein kinase binding Human InterPro:IPR015429 CCND1 BHF-UCL UniProtKB {GO:0005515=PMID:21988832, GO:0043627=GO_REF:0000019, GO:0010165=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0031100=GO_REF:0000019, GO:0030178=GO_REF:0000019, GO:0045737=PMID:8114739, GO:0005634=PMID:11793365, GO:0032403=GO_REF:0000019, GO:2000045=GO_REF:0000019, GO:0005829=Reactome:REACT_2142, GO:0030968=GO_REF:0000019, GO:0005622=GO_REF:0000054, GO:0000084=Reactome:REACT_899, GO:0000082=PMID:18483258, GO:0030857=GO_REF:0000019, GO:0010039=GO_REF:0000019, GO:0032026=GO_REF:0000019, GO:0045444=GO_REF:0000019, GO:0033197=GO_REF:0000019, GO:0016538=GO_REF:0000019, GO:0000080=Reactome:REACT_1590, GO:0000320=GO_REF:0000019, GO:0060070=GO_REF:0000019, GO:0051412=GO_REF:0000019, GO:0019901=PMID:8114739, GO:0042493=PMID:18291362, GO:0010243=GO_REF:0000019, GO:0006974=PMID:19412162, GO:0070141=PMID:18483258, GO:0001889=GO_REF:0000019, GO:0051592=GO_REF:0000019, GO:0033598=GO_REF:0000019, GO:0004672=GO_REF:0000019, GO:0016020=GO_REF:0000039, GO:0007595=GO_REF:0000019, GO:0000307=PMID:17420273, GO:0001934=PMID:8114739, GO:0033327=GO_REF:0000019, GO:0005654=Reactome:REACT_111248, GO:0031571=PMID:19412162, GO:0005923=GO_REF:0000019, GO:0000278=Reactome:REACT_152, GO:0019899=PMID:19412162, GO:0033601=GO_REF:0000019, GO:0060749=GO_REF:0000019, GO:0051301=GO_REF:0000037} P24385 G1/S-specific cyclin-D1 protein 20081126 {GO:0005515=IPI, GO:0043627=IEA, GO:0010165=IEA, GO:0045471=IEA, GO:0031100=IEA, GO:0030178=IEA, GO:0045737=IDA, GO:0005634=IDA, GO:0032403=IEA, GO:2000045=IEA, GO:0005829=TAS, GO:0030968=IEA, GO:0005622=IDA, GO:0000084=TAS, GO:0000082=TAS, GO:0030857=IEA, GO:0010039=IEA, GO:0032026=IEA, GO:0045444=IEA, GO:0033197=IEA, GO:0016538=IEA, GO:0000080=TAS, GO:0000320=IEA, GO:0060070=IEA, GO:0051412=IEA, GO:0019901=IPI, GO:0042493=IEP, GO:0010243=IEA, GO:0006974=IDA, GO:0070141=IDA, GO:0001889=IEA, GO:0051592=IEA, GO:0033598=IEA, GO:0004672=IEA, GO:0016020=IEA, GO:0007595=IEA, GO:0000307=IDA, GO:0001934=IDA, GO:0033327=IEA, GO:0005654=TAS, GO:0031571=IDA, GO:0005923=IEA, GO:0000278=TAS, GO:0019899=IPI, GO:0033601=IEA, GO:0060749=IEA, GO:0051301=IEA} G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, Leydig cell differentiation, S phase of mitotic cell cycle, canonical Wnt receptor signaling pathway, cell division, endoplasmic reticulum unfolded protein response, fat cell differentiation, lactation, liver development, mammary gland alveolus development, mammary gland epithelial cell proliferation, mitotic G1 DNA damage checkpoint, mitotic cell cycle, negative regulation of Wnt receptor signaling pathway, negative regulation of epithelial cell differentiation, organ regeneration, positive regulation of cyclin-dependent protein kinase activity, positive regulation of mammary gland epithelial cell proliferation, positive regulation of protein phosphorylation, re-entry into mitotic cell cycle, regulation of G1/S transition of mitotic cell cycle, response to DNA damage stimulus, response to UV-A, response to X-ray, response to calcium ion, response to corticosterone stimulus, response to drug, response to estrogen stimulus, response to ethanol, response to iron ion, response to magnesium ion, response to organic nitrogen, response to vitamin E cyclin-dependent protein kinase holoenzyme complex, cytosol, intracellular, membrane, nucleoplasm, nucleus, tight junction cyclin-dependent protein serine/threonine kinase regulator activity, enzyme binding, protein binding, protein complex binding, protein kinase activity, protein kinase binding Human CCND2 HPA UniProtKB {GO:0031965=PMID:18827403, GO:0007049=GO_REF:0000037, GO:0019901=PMID:8114739, GO:0000307=PMID:8114739, GO:0001934=PMID:8114739, GO:0005730=GO_REF:0000052, GO:0045737=PMID:8114739, GO:0005634=GO_REF:0000052, GO:0000785=PMID:18827403, GO:0005829=PMID:18827403, GO:0051301=GO_REF:0000037} P30279 G1/S-specific cyclin-D2 protein 20120912 {GO:0031965=IDA, GO:0007049=IEA, GO:0019901=IPI, GO:0000307=IDA, GO:0001934=IDA, GO:0005730=IDA, GO:0045737=IDA, GO:0005634=IDA, GO:0000785=IDA, GO:0005829=IDA, GO:0051301=IEA} cell cycle, cell division, positive regulation of cyclin-dependent protein kinase activity, positive regulation of protein phosphorylation chromatin, cyclin-dependent protein kinase holoenzyme complex, cytosol, nuclear membrane, nucleolus, nucleus protein kinase binding NOT Human CCND3 InterPro UniProtKB {GO:0005515=PMID:21988832, GO:0019901=PMID:8114739, GO:0045737=PMID:8114739, GO:0005634=GO_REF:0000002, GO:0007165=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0042098=GO_REF:0000019, GO:0016020=GO_REF:0000039, GO:0000307=PMID:8114739, GO:0051726=GO_REF:0000019, GO:0001934=PMID:8114739, GO:0004693=GO_REF:0000019, GO:0051301=GO_REF:0000037} Q5T8J1 G1/S-specific cyclin-D3 protein 20130413 {GO:0005515=IPI, GO:0019901=IPI, GO:0045737=IDA, GO:0005634=IEA, GO:0007165=IEA, GO:0005737=IEA, GO:0042098=IEA, GO:0016020=IEA, GO:0000307=IDA, GO:0051726=IEA, GO:0001934=IDA, GO:0004693=IEA, GO:0051301=IEA} T cell proliferation, cell division, positive regulation of cyclin-dependent protein kinase activity, positive regulation of protein phosphorylation, regulation of cell cycle, signal transduction cyclin-dependent protein kinase holoenzyme complex, cytoplasm, membrane, nucleus cyclin-dependent protein serine/threonine kinase activity, protein binding, protein kinase binding Human InterPro:IPR004367 CCNDBP1 IntAct UniProtKB {GO:0005515=PMID:10915743, GO:0005737=GO_REF:0000039, GO:0007049=GO_REF:0000037, GO:0051726=GO_REF:0000002, GO:0005634=PMID:12437976} O95273 Cyclin-D1-binding protein 1 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0007049=IEA, GO:0051726=IEA, GO:0005634=IDA} cell cycle, regulation of cell cycle cytoplasm, nucleus protein binding Human UniProtKB:P15923-1 CCNE1 HPA UniProtKB {GO:0005515=PMID:23455922, GO:0019901=GO_REF:0000019, GO:0003713=PMID:15572661, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0050681=PMID:15572661, GO:0000079=GO_REF:0000002, GO:0005829=Reactome:REACT_1683, GO:0000082=Reactome:REACT_1783, GO:0000083=Reactome:REACT_683, GO:0016301=GO_REF:0000019, GO:0006270=GO_REF:0000019, GO:0000307=GO_REF:0000019, GO:0005654=Reactome:REACT_22145, GO:0006468=PMID:10500095, GO:0016538=GO_REF:0000019, GO:0000278=Reactome:REACT_152, GO:0016055=GO_REF:0000019, GO:0045893=PMID:15572661, GO:0030521=PMID:15572661, GO:0051301=GO_REF:0000037} P24864 G1/S-specific cyclin-E1 protein 20120912 {GO:0005515=IPI, GO:0019901=IEA, GO:0003713=NAS, GO:0005730=IDA, GO:0005634=IDA, GO:0050681=NAS, GO:0000079=IEA, GO:0005829=TAS, GO:0000082=TAS, GO:0000083=TAS, GO:0016301=IEA, GO:0006270=IEA, GO:0000307=IEA, GO:0005654=TAS, GO:0006468=IMP, GO:0016538=IEA, GO:0000278=TAS, GO:0016055=IEA, GO:0045893=NAS, GO:0030521=NAS, GO:0051301=IEA} DNA replication initiation, G1/S transition of mitotic cell cycle, Wnt receptor signaling pathway, androgen receptor signaling pathway, cell division, mitotic cell cycle, positive regulation of transcription, DNA-dependent, protein phosphorylation, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of transcription involved in G1/S phase of mitotic cell cycle cyclin-dependent protein kinase holoenzyme complex, cytosol, nucleolus, nucleoplasm, nucleus androgen receptor binding, cyclin-dependent protein serine/threonine kinase regulator activity, kinase activity, protein binding, protein kinase binding, transcription coactivator activity NOT Human CCNE2 UniProtKB UniProtKB {GO:0005515=PMID:23455922, GO:0019901=GO_REF:0000002, GO:0005634=GO_REF:0000002, GO:0000079=GO_REF:0000002, GO:0005829=Reactome:REACT_1683, GO:0000082=Reactome:REACT_1783, GO:0007049=GO_REF:0000038, GO:0006270=GO_REF:0000019, GO:0000075=PMID:9858585, GO:0016538=GO_REF:0000019, GO:0005654=Reactome:REACT_9067, GO:0000278=Reactome:REACT_152, GO:0051301=GO_REF:0000038} Q8WUE3 G1/S-specific cyclin-E2 protein 20130413 {GO:0005515=IPI, GO:0019901=IEA, GO:0005634=IEA, GO:0000079=IEA, GO:0005829=TAS, GO:0000082=TAS, GO:0007049=IEA, GO:0006270=IEA, GO:0000075=TAS, GO:0016538=IEA, GO:0005654=TAS, GO:0000278=TAS, GO:0051301=IEA} DNA replication initiation, G1/S transition of mitotic cell cycle, cell cycle, cell cycle checkpoint, cell division, mitotic cell cycle, regulation of cyclin-dependent protein serine/threonine kinase activity cytosol, nucleoplasm, nucleus cyclin-dependent protein serine/threonine kinase regulator activity, protein binding, protein kinase binding Human UniProtKB-KW:KW-0132 CCNF IntAct UniProtKB {GO:0005515=PMID:22632967, GO:0007067=GO_REF:0000037, GO:0016567=PMID:20596027, GO:0005814=PMID:20596027, GO:0010826=PMID:20596027, GO:0005634=PMID:20596027, GO:0001890=GO_REF:0000019, GO:0031146=PMID:20596027, GO:0000320=GO_REF:0000019, GO:0019005=PMID:20596027, GO:0051301=GO_REF:0000037} P41002 Cyclin-F protein 20130415 {GO:0005515=IPI, GO:0007067=IEA, GO:0016567=IDA, GO:0005814=IDA, GO:0010826=IDA, GO:0005634=IDA, GO:0001890=IEA, GO:0031146=IDA, GO:0000320=IEA, GO:0019005=IDA, GO:0051301=IEA} SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, cell division, mitosis, negative regulation of centrosome duplication, placenta development, protein ubiquitination, re-entry into mitotic cell cycle SCF ubiquitin ligase complex, centriole, nucleus protein binding Human UniProtKB:P63208 CCNG1 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0007095=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0010243=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0000079=PMID:8626390, GO:0030425=GO_REF:0000019, GO:0007067=GO_REF:0000037, GO:0006949=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0016049=GO_REF:0000019, GO:0051301=GO_REF:0000037} P51959 Cyclin-G1 protein 20130415 {GO:0005515=IPI, GO:0007095=IEA, GO:0043066=IEA, GO:0048471=IEA, GO:0019904=IEA, GO:0010243=IEA, GO:0005634=IEA, GO:0000079=TAS, GO:0030425=IEA, GO:0007067=IEA, GO:0006949=IEA, GO:0007420=IEA, GO:0043025=IEA, GO:0016049=IEA, GO:0051301=IEA} brain development, cell division, cell growth, mitosis, mitotic G2 DNA damage checkpoint, negative regulation of apoptotic process, regulation of cyclin-dependent protein serine/threonine kinase activity, response to organic nitrogen, syncytium formation dendrite, neuronal cell body, nucleus, perinuclear region of cytoplasm protein binding, protein domain specific binding Human UniProtKB:Q15025 CCNG2 PINC UniProtKB {GO:0005737=GO_REF:0000039, GO:0007067=GO_REF:0000037, GO:0051726=GO_REF:0000019, GO:0000075=PMID:8626390, GO:0051301=GO_REF:0000037} Q16589 Cyclin-G2 protein 20030904 {GO:0005737=IEA, GO:0007067=IEA, GO:0051726=IEA, GO:0000075=TAS, GO:0051301=IEA} cell cycle checkpoint, cell division, mitosis, regulation of cell cycle cytoplasm Human CCNH GOC UniProtKB {GO:0005515=PMID:21988832, GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006368=Reactome:REACT_2089, GO:0006367=Reactome:REACT_1851, GO:0006366=Reactome:REACT_1366, GO:0006363=Reactome:REACT_1074, GO:0006362=Reactome:REACT_2204, GO:0006361=Reactome:REACT_1974, GO:0006360=Reactome:REACT_1309, GO:0005634=PMID:7936635, GO:0000079=GO_REF:0000002, GO:0070985=GO_REF:0000002, GO:0000084=Reactome:REACT_899, GO:0000082=Reactome:REACT_1783, GO:0016301=GO_REF:0000019, GO:0045944=PMID:8692841, GO:0000086=Reactome:REACT_2203, GO:0016032=Reactome:REACT_6256, GO:0016538=GO_REF:0000002, GO:0000080=Reactome:REACT_1590, GO:0008094=PMID:9852112, GO:0019907=PMID:8692842, GO:0006355=GO_REF:0000002, GO:0019901=GO_REF:0000002, GO:0006370=Reactome:REACT_1470, GO:0008353=PMID:9852112, GO:0006351=GO_REF:0000002, GO:0050434=Reactome:REACT_6162, GO:0004672=PMID:9852112, GO:0006281=Reactome:REACT_216, GO:0006283=Reactome:REACT_1628, GO:0006468=PMID:9852112, GO:0005654=Reactome:REACT_9070, GO:0006289=Reactome:REACT_1826, GO:0000278=Reactome:REACT_152, GO:0000718=Reactome:REACT_311, GO:0005675=PMID:9852112} P51946 Cyclin-H protein 20130413 {GO:0005515=IPI, GO:0022415=TAS, GO:0010467=TAS, GO:0006368=TAS, GO:0006367=TAS, GO:0006366=TAS, GO:0006363=TAS, GO:0006362=TAS, GO:0006361=TAS, GO:0006360=TAS, GO:0005634=TAS, GO:0000079=IEA, GO:0070985=IEA, GO:0000084=TAS, GO:0000082=TAS, GO:0016301=IEA, GO:0045944=IDA, GO:0000086=TAS, GO:0016032=TAS, GO:0016538=IEA, GO:0000080=TAS, GO:0008094=IDA, GO:0019907=IDA, GO:0006355=IEA, GO:0019901=IEA, GO:0006370=TAS, GO:0008353=IDA, GO:0006351=IEA, GO:0050434=TAS, GO:0004672=IDA, GO:0006281=TAS, GO:0006283=TAS, GO:0006468=IDA, GO:0005654=TAS, GO:0006289=TAS, GO:0000278=TAS, GO:0000718=TAS, GO:0005675=IDA} 7-methylguanosine mRNA capping, DNA repair, G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, G2/M transition of mitotic cell cycle, S phase of mitotic cell cycle, gene expression, mitotic cell cycle, nucleotide-excision repair, nucleotide-excision repair, DNA damage removal, positive regulation of transcription from RNA polymerase II promoter, positive regulation of viral transcription, protein phosphorylation, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of transcription, DNA-dependent, termination of RNA polymerase I transcription, transcription elongation from RNA polymerase I promoter, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase I promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase I promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transcription-coupled nucleotide-excision repair, viral reproduction, viral reproductive process TFIIK complex, cyclin-dependent protein kinase activating kinase holoenzyme complex, holo TFIIH complex, nucleoplasm, nucleus DNA-dependent ATPase activity, RNA polymerase II carboxy-terminal domain kinase activity, cyclin-dependent protein serine/threonine kinase regulator activity, kinase activity, protein binding, protein kinase activity, protein kinase binding Human CCNI UniProtKB UniProtKB {GO:0007283=PMID:9705831} Q14094 Cyclin-I protein 20021113 {GO:0007283=NAS} spermatogenesis Human CCNJ InterPro UniProtKB {GO:0005634=GO_REF:0000002} Q5T5M9 Cyclin-J protein 20130413 {GO:0005634=IEA} nucleus Human InterPro:IPR004367 CCNK IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0071157=PMID:9632813, GO:0006355=GO_REF:0000037, GO:0019901=PMID:22012619, GO:0006366=PMID:9632813, GO:0000079=GO_REF:0000002, GO:0008353=PMID:9632813, GO:0006974=PMID:22012619, GO:0002945=PMID:22012619, GO:0007067=GO_REF:0000037, GO:0002944=PMID:22012619, GO:0051301=GO_REF:0000037, GO:0004693=PMID:9632813} O75909 Cyclin-K protein 20130415 {GO:0005515=IPI, GO:0071157=IGI, GO:0006355=IEA, GO:0019901=IPI, GO:0006366=TAS, GO:0000079=IEA, GO:0008353=IDA, GO:0006974=IMP, GO:0002945=IPI, GO:0007067=IEA, GO:0002944=IPI, GO:0051301=IEA, GO:0004693=IDA} cell division, mitosis, negative regulation of cell cycle arrest, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of transcription, DNA-dependent, response to DNA damage stimulus, transcription from RNA polymerase II promoter cyclin K-CDK12 complex, cyclin K-CDK13 complex RNA polymerase II carboxy-terminal domain kinase activity, cyclin-dependent protein serine/threonine kinase activity, protein binding, protein kinase binding Human UniProtKB:P54253 CCNL1 MGI UniProtKB {GO:0006396=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0016607=GO_REF:0000039, GO:0019901=GO_REF:0000002, GO:0005634=PMID:17494991, GO:0000079=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q9UK58 Cyclin-L1 protein 20130220 {GO:0006396=IEA, GO:0006355=IEA, GO:0016607=IEA, GO:0019901=IEA, GO:0005634=IDA, GO:0000079=IEA, GO:0006351=IEA} RNA processing, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of transcription, DNA-dependent, transcription, DNA-dependent nuclear speck, nucleus protein kinase binding Human CCNL2 MGI UniProtKB {GO:0006396=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0016607=GO_REF:0000039, GO:0019901=GO_REF:0000002, GO:0005634=PMID:17494991, GO:0000079=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q96S94 Cyclin-L2 protein 20120321 {GO:0006396=IEA, GO:0006355=IEA, GO:0016607=IEA, GO:0019901=IEA, GO:0005634=IDA, GO:0000079=IEA, GO:0006351=IEA} RNA processing, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of transcription, DNA-dependent, transcription, DNA-dependent nuclear speck, nucleus protein kinase binding Human CCNO Reactome UniProtKB {GO:0004844=PMID:12161446, GO:0007049=PMID:8419333, GO:0006281=Reactome:REACT_216, GO:0019901=GO_REF:0000002, GO:0006284=Reactome:REACT_1104, GO:0045008=Reactome:REACT_2156, GO:0006285=Reactome:REACT_804, GO:0005654=Reactome:REACT_1630, GO:0000079=GO_REF:0000002, GO:0051301=PMID:8419333} P22674 Cyclin-O protein 20130213 {GO:0004844=IDA, GO:0007049=IDA, GO:0006281=TAS, GO:0019901=IEA, GO:0006284=TAS, GO:0045008=TAS, GO:0006285=TAS, GO:0005654=TAS, GO:0000079=IEA, GO:0051301=IDA} DNA repair, base-excision repair, base-excision repair, AP site formation, cell cycle, cell division, depyrimidination, regulation of cyclin-dependent protein serine/threonine kinase activity nucleoplasm protein kinase binding, uracil DNA N-glycosylase activity Human CCNT1 HPA UniProtKB {GO:0005515=PMID:22190034, GO:0010467=Reactome:REACT_71, GO:0022415=Reactome:REACT_6361, GO:0006368=Reactome:REACT_1845, GO:0006367=Reactome:REACT_12627, GO:0044212=GO_REF:0000019, GO:0006366=Reactome:REACT_1366, GO:0005634=GO_REF:0000052, GO:0000079=GO_REF:0000002, GO:0045944=Reactome:REACT_120734, GO:0016032=Reactome:REACT_6256, GO:0007179=Reactome:REACT_6844, GO:0008024=PMID:15905409, GO:0019901=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0003677=PMID:16109376, GO:0006351=Reactome:REACT_121061, GO:0050434=Reactome:REACT_6162, GO:0007049=GO_REF:0000037, GO:0003682=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0017069=GO_REF:0000019, GO:0006468=PMID:16109376, GO:0005654=Reactome:REACT_121336, GO:0051301=GO_REF:0000037} O60563 Cyclin-T1 protein 20080818 {GO:0005515=IPI, GO:0010467=TAS, GO:0022415=TAS, GO:0006368=TAS, GO:0006367=TAS, GO:0044212=IEA, GO:0006366=TAS, GO:0005634=IDA, GO:0000079=IEA, GO:0045944=TAS, GO:0016032=TAS, GO:0007179=TAS, GO:0008024=IDA, GO:0019901=IEA, GO:0005730=IDA, GO:0003677=IDA, GO:0006351=TAS, GO:0050434=TAS, GO:0007049=IEA, GO:0003682=IEA, GO:0019048=IEA, GO:0017069=IEA, GO:0006468=IPI, GO:0005654=TAS, GO:0051301=IEA} cell cycle, cell division, gene expression, positive regulation of transcription from RNA polymerase II promoter, positive regulation of viral transcription, protein phosphorylation, regulation of cyclin-dependent protein serine/threonine kinase activity, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, viral reproduction, viral reproductive process, virus-host interaction nucleolus, nucleoplasm, nucleus, positive transcription elongation factor complex b DNA binding, chromatin binding, protein binding, protein kinase binding, snRNA binding, transcription regulatory region DNA binding NOT Human CCNT2 Reactome UniProtKB {GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000002, GO:0006368=Reactome:REACT_1845, GO:0006367=Reactome:REACT_12627, GO:0019901=GO_REF:0000002, GO:0006366=Reactome:REACT_1366, GO:0005634=PMID:16109376, GO:0000079=GO_REF:0000002, GO:0006351=Reactome:REACT_121061, GO:0007049=GO_REF:0000037, GO:0045944=Reactome:REACT_120734, GO:0019048=GO_REF:0000037, GO:0016032=Reactome:REACT_6256, GO:0005654=Reactome:REACT_121336, GO:0007179=Reactome:REACT_6844, GO:0051301=GO_REF:0000037} O60583 Cyclin-T2 protein 20130301 {GO:0022415=TAS, GO:0010467=TAS, GO:0006355=IEA, GO:0006368=TAS, GO:0006367=TAS, GO:0019901=IEA, GO:0006366=TAS, GO:0005634=IDA, GO:0000079=IEA, GO:0006351=TAS, GO:0007049=IEA, GO:0045944=TAS, GO:0019048=IEA, GO:0016032=TAS, GO:0005654=TAS, GO:0007179=TAS, GO:0051301=IEA} cell cycle, cell division, gene expression, positive regulation of transcription from RNA polymerase II promoter, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of transcription, DNA-dependent, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, viral reproduction, viral reproductive process, virus-host interaction nucleoplasm, nucleus protein kinase binding Human CCNY LIFEdb UniProtKB {GO:0005515=PMID:19524571, GO:0005886=PMID:19524571, GO:0019901=GO_REF:0000002, GO:0000086=PMID:20059949, GO:0000308=PMID:20059949, GO:0045737=PMID:20059949, GO:0005634=GO_REF:0000054, GO:0016538=PMID:20059949, GO:0000079=GO_REF:0000002, GO:0016055=GO_REF:0000037, GO:0060828=PMID:20059949, GO:0051301=GO_REF:0000037} Q8ND76 Cyclin-Y protein 20100607 {GO:0005515=IPI, GO:0005886=IDA, GO:0019901=IEA, GO:0000086=IDA, GO:0000308=IDA, GO:0045737=IDA, GO:0005634=IDA, GO:0016538=IDA, GO:0000079=IEA, GO:0016055=IEA, GO:0060828=IDA, GO:0051301=IEA} G2/M transition of mitotic cell cycle, Wnt receptor signaling pathway, cell division, positive regulation of cyclin-dependent protein kinase activity, regulation of canonical Wnt receptor signaling pathway, regulation of cyclin-dependent protein serine/threonine kinase activity cytoplasmic cyclin-dependent protein kinase holoenzyme complex, nucleus, plasma membrane cyclin-dependent protein serine/threonine kinase regulator activity, protein binding, protein kinase binding Human CCNYL1 InterPro UniProtKB {GO:0019901=GO_REF:0000002, GO:0000079=GO_REF:0000002} Q8N7R7 Cyclin-Y-like protein 1 protein 20130413 {GO:0019901=IEA, GO:0000079=IEA} regulation of cyclin-dependent protein serine/threonine kinase activity protein kinase binding Human InterPro:IPR012399 CCP110 IntAct UniProtKB {GO:0005515=PMID:21620453, GO:0051298=PMID:20596027, GO:0005813=PMID:21399614, GO:0032465=PMID:16760425, GO:0007099=PMID:17681131, GO:0005814=PMID:20596027, GO:0000086=Reactome:REACT_2203, GO:0030030=GO_REF:0000037, GO:0000278=Reactome:REACT_152, GO:0005829=Reactome:REACT_15470} O43303 Centriolar coiled-coil protein of 110 kDa protein 20130415 {GO:0005515=IPI, GO:0051298=IDA, GO:0005813=IDA, GO:0032465=IMP, GO:0007099=IMP, GO:0005814=IDA, GO:0000086=TAS, GO:0030030=IEA, GO:0000278=TAS, GO:0005829=TAS} G2/M transition of mitotic cell cycle, cell projection organization, centriole replication, centrosome duplication, mitotic cell cycle, regulation of cytokinesis centriole, centrosome, cytosol protein binding Human UniProtKB:Q8IW35 CCPG1 UniProtKB UniProtKB {GO:0007049=GO_REF:0000037, GO:0016020=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:2001106=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q9ULG6 Cell cycle progression protein 1 protein 20130413 {GO:0007049=IEA, GO:0016020=IEA, GO:0045944=IEA, GO:2001106=IEA, GO:0016021=IEA} cell cycle, positive regulation of transcription from RNA polymerase II promoter, regulation of Rho guanyl-nucleotide exchange factor activity integral to membrane, membrane Human UniProtKB-KW:KW-0812 CCR1 BHF-UCL UniProtKB {GO:0071791=PMID:10660125, GO:0005515=PMID:15001559, GO:0005886=Reactome:REACT_22289, GO:0051928=PMID:15764707, GO:0019221=PMID:15474493, GO:0007267=PMID:10734056, GO:0006887=PMID:10734056, GO:0007204=PMID:10734056, GO:0019957=PMID:8699119, GO:0006955=PMID:10734056, GO:0006954=GO_REF:0000002, GO:0006935=PMID:15474493, GO:0004950=PMID:10660125, GO:0006816=PMID:10734056, GO:0007155=PMID:10910894, GO:0070098=PMID:21403648, GO:0002407=PMID:16621978, GO:0009611=PMID:7505609, GO:0006874=PMID:10734056, GO:0045672=PMID:21403648, GO:0004435=PMID:10734056, GO:0005887=PMID:7505609, GO:0007187=PMID:7505609, GO:0035717=PMID:10660125, GO:0016493=PMID:10734056, GO:0090026=PMID:18587271, GO:0007166=PMID:10770925} P32246 C-C chemokine receptor type 1 protein 20110322 {GO:0071791=IPI, GO:0005515=IPI, GO:0005886=TAS, GO:0051928=IDA, GO:0019221=NAS, GO:0007267=IDA, GO:0006887=IDA, GO:0007204=IDA, GO:0019957=IPI, GO:0006955=IDA, GO:0006954=IEA, GO:0006935=NAS, GO:0004950=IDA, GO:0006816=IDA, GO:0007155=TAS, GO:0070098=IDA, GO:0002407=TAS, GO:0009611=TAS, GO:0006874=IDA, GO:0045672=IMP, GO:0004435=IDA, GO:0005887=TAS, GO:0007187=TAS, GO:0035717=IPI, GO:0016493=IDA, GO:0090026=IDA, GO:0007166=TAS} G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, calcium ion transport, cell adhesion, cell surface receptor signaling pathway, cell-cell signaling, cellular calcium ion homeostasis, chemokine-mediated signaling pathway, chemotaxis, cytokine-mediated signaling pathway, dendritic cell chemotaxis, elevation of cytosolic calcium ion concentration, exocytosis, immune response, inflammatory response, positive regulation of calcium ion transport, positive regulation of monocyte chemotaxis, positive regulation of osteoclast differentiation, response to wounding integral to plasma membrane, plasma membrane C-C chemokine binding, C-C chemokine receptor activity, chemokine (C-C motif) ligand 5 binding, chemokine (C-C motif) ligand 7 binding, chemokine receptor activity, phosphatidylinositol phospholipase C activity, protein binding Human CCR10 Reactome UniProtKB {GO:0006955=GO_REF:0000002, GO:0005886=Reactome:REACT_22289, GO:0007186=PMID:7851889, GO:0006935=GO_REF:0000019, GO:0005887=PMID:7851889, GO:0004930=PMID:7851889, GO:0016493=GO_REF:0000019, GO:0016021=GO_REF:0000002, GO:0007204=GO_REF:0000019, GO:0019957=GO_REF:0000002} P46092 C-C chemokine receptor type 10 protein 20100217 {GO:0006955=IEA, GO:0005886=TAS, GO:0007186=TAS, GO:0006935=IEA, GO:0005887=TAS, GO:0004930=TAS, GO:0016493=IEA, GO:0016021=IEA, GO:0007204=IEA, GO:0019957=IEA} G-protein coupled receptor signaling pathway, chemotaxis, elevation of cytosolic calcium ion concentration, immune response integral to membrane, integral to plasma membrane, plasma membrane C-C chemokine binding, C-C chemokine receptor activity, G-protein coupled receptor activity Human CCR2 BHF-UCL UniProtKB {GO:0043310=GO_REF:0000024, GO:0019221=PMID:15995708, GO:2000451=GO_REF:0000024, GO:0090265=GO_REF:0000024, GO:0019957=GO_REF:0000002, GO:0042803=GO_REF:0000024, GO:0006935=PMID:10623817, GO:0031727=PMID:15995708, GO:0004950=PMID:10623817, GO:0043025=GO_REF:0000024, GO:0035705=GO_REF:0000024, GO:0046641=GO_REF:0000024, GO:0032729=GO_REF:0000024, GO:0070098=GO_REF:0000024, GO:0042535=GO_REF:0000024, GO:2000464=PMID:12271471, GO:0005887=PMID:8146186, GO:0045087=Reactome:REACT_6802, GO:0050870=GO_REF:0000024, GO:0016493=GO_REF:0000002, GO:0090026=GO_REF:0000024, GO:2000473=GO_REF:0000024, GO:0048471=GO_REF:0000024, GO:0005886=Reactome:REACT_115754, GO:2000439=GO_REF:0000024, GO:0007194=GO_REF:0000002, GO:0007204=GO_REF:0000002, GO:0030425=GO_REF:0000024, GO:0005829=GO_REF:0000024, GO:0006955=PMID:10751368, GO:0005737=PMID:15995708, GO:0006954=GO_REF:0000002, GO:0002829=GO_REF:0000024, GO:0002827=GO_REF:0000024, GO:0043204=GO_REF:0000024, GO:0019725=GO_REF:0000024, GO:0032743=GO_REF:0000024, GO:0010820=GO_REF:0000024, GO:0002407=PMID:16621978, GO:0009611=PMID:8146186, GO:0006874=GO_REF:0000024, GO:0007259=PMID:9670957, GO:0010574=GO_REF:0000024, GO:0006968=PMID:10201901, GO:0001974=GO_REF:0000024, GO:0019048=GO_REF:0000037, GO:0016525=GO_REF:0000024, GO:0050729=GO_REF:0000024, GO:0016021=PMID:8530354} P41597 C-C chemokine receptor type 2 protein 20110225 {GO:0043310=ISS, GO:0019221=IDA, GO:2000451=ISS, GO:0090265=ISS, GO:0019957=IEA, GO:0042803=ISS, GO:0006935=TAS, GO:0031727=IDA, GO:0004950=TAS, GO:0043025=ISS, GO:0035705=ISS, GO:0046641=ISS, GO:0032729=ISS, GO:0070098=ISS, GO:0042535=ISS, GO:2000464=IDA, GO:0005887=TAS, GO:0045087=TAS, GO:0050870=ISS, GO:0016493=IEA, GO:0090026=ISS, GO:2000473=ISS, GO:0048471=ISS, GO:0005886=TAS, GO:2000439=ISS, GO:0007194=IEA, GO:0007204=IEA, GO:0030425=ISS, GO:0005829=ISS, GO:0006955=TAS, GO:0005737=IDA, GO:0006954=IEA, GO:0002829=ISS, GO:0002827=ISS, GO:0043204=ISS, GO:0019725=ISS, GO:0032743=ISS, GO:0010820=ISS, GO:0002407=TAS, GO:0009611=TAS, GO:0006874=ISS, GO:0007259=TAS, GO:0010574=ISS, GO:0006968=TAS, GO:0001974=ISS, GO:0019048=IEA, GO:0016525=ISS, GO:0050729=ISS, GO:0016021=TAS} JAK-STAT cascade, T-helper 17 cell chemotaxis, blood vessel remodeling, cellular calcium ion homeostasis, cellular defense response, cellular homeostasis, chemokine-mediated signaling pathway, chemotaxis, cytokine-mediated signaling pathway, dendritic cell chemotaxis, elevation of cytosolic calcium ion concentration, immune response, inflammatory response, innate immune response, negative regulation of adenylate cyclase activity, negative regulation of angiogenesis, negative regulation of eosinophil degranulation, negative regulation of type 2 immune response, positive regulation of CD8-positive, alpha-beta T cell extravasation, positive regulation of T cell activation, positive regulation of T cell chemotaxis, positive regulation of T-helper 1 type immune response, positive regulation of alpha-beta T cell proliferation, positive regulation of astrocyte chemotaxis, positive regulation of hematopoietic stem cell migration, positive regulation of immune complex clearance by monocytes and macrophages, positive regulation of inflammatory response, positive regulation of interferon-gamma production, positive regulation of interleukin-2 production, positive regulation of monocyte chemotaxis, positive regulation of monocyte extravasation, positive regulation of tumor necrosis factor biosynthetic process, regulation of vascular endothelial growth factor production, response to wounding, virus-host interaction cytoplasm, cytosol, dendrite, integral to membrane, integral to plasma membrane, neuronal cell body, perikaryon, perinuclear region of cytoplasm, plasma membrane C-C chemokine binding, C-C chemokine receptor activity, CCR2 chemokine receptor binding, chemokine receptor activity, protein homodimerization activity Human UniProtKB:O55193 CCR3 ENSEMBL UniProtKB {GO:0070098=PMID:10415069, GO:0005886=GO_REF:0000019, GO:0007204=GO_REF:0000002, GO:0005615=GO_REF:0000019, GO:0019957=GO_REF:0000002, GO:0045766=GO_REF:0000019, GO:0006968=PMID:10713092, GO:0006954=GO_REF:0000002, GO:0006935=GO_REF:0000002, GO:0001938=GO_REF:0000019, GO:0005887=PMID:9302298, GO:0019048=GO_REF:0000037, GO:0002551=GO_REF:0000019, GO:0004950=PMID:10415069, GO:0048245=GO_REF:0000019, GO:0007188=PMID:10201960, GO:0016493=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0007155=PMID:10201960, GO:0070371=GO_REF:0000019, GO:0005768=GO_REF:0000019, GO:0035476=GO_REF:0000019} Q8TDP5 CC chemokine receptor 3 protein 20130413 {GO:0070098=TAS, GO:0005886=IEA, GO:0007204=IEA, GO:0005615=IEA, GO:0019957=IEA, GO:0045766=IEA, GO:0006968=TAS, GO:0006954=IEA, GO:0006935=IEA, GO:0001938=IEA, GO:0005887=TAS, GO:0019048=IEA, GO:0002551=IEA, GO:0004950=TAS, GO:0048245=IEA, GO:0007188=TAS, GO:0016493=IEA, GO:0016021=IEA, GO:0007155=TAS, GO:0070371=IEA, GO:0005768=IEA, GO:0035476=IEA} ERK1 and ERK2 cascade, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, angioblast cell migration, cell adhesion, cellular defense response, chemokine-mediated signaling pathway, chemotaxis, elevation of cytosolic calcium ion concentration, eosinophil chemotaxis, inflammatory response, mast cell chemotaxis, positive regulation of angiogenesis, positive regulation of endothelial cell proliferation, virus-host interaction endosome, extracellular space, integral to membrane, integral to plasma membrane, plasma membrane C-C chemokine binding, C-C chemokine receptor activity, chemokine receptor activity Human Ensembl:ENSRNOP00000008809 CCR4 GOC UniProtKB {GO:0070098=PMID:7642634, GO:0005886=Reactome:REACT_22289, GO:0002507=GO_REF:0000019, GO:0007204=GO_REF:0000002, GO:0019957=GO_REF:0000002, GO:0006955=GO_REF:0000002, GO:0006954=GO_REF:0000019, GO:0006935=GO_REF:0000019, GO:0005887=PMID:7642634, GO:0004950=PMID:7642634, GO:0016493=GO_REF:0000019, GO:0001764=GO_REF:0000019, GO:0009897=GO_REF:0000019} P51679 C-C chemokine receptor type 4 protein 20130413 {GO:0070098=TAS, GO:0005886=TAS, GO:0002507=IEA, GO:0007204=IEA, GO:0019957=IEA, GO:0006955=IEA, GO:0006954=IEA, GO:0006935=IEA, GO:0005887=TAS, GO:0004950=TAS, GO:0016493=IEA, GO:0001764=IEA, GO:0009897=IEA} chemokine-mediated signaling pathway, chemotaxis, elevation of cytosolic calcium ion concentration, immune response, inflammatory response, neuron migration, tolerance induction external side of plasma membrane, integral to plasma membrane, plasma membrane C-C chemokine binding, C-C chemokine receptor activity, chemokine receptor activity Human CCR5 GOC UniProtKB {GO:0071791=PMID:8699119, GO:0005515=PMID:15001559, GO:0022415=Reactome:REACT_6266, GO:0019722=PMID:19523456, GO:0005886=Reactome:REACT_22289, GO:0030260=Reactome:REACT_6903, GO:0030818=GO_REF:0000002, GO:0007267=PMID:10679098, GO:0007204=PMID:10201901, GO:0019957=PMID:8699119, GO:0006955=GO_REF:0000002, GO:0005737=PMID:10415069, GO:0006954=GO_REF:0000002, GO:0006935=PMID:10741397, GO:0000165=PMID:12032188, GO:0004950=PMID:10201901, GO:0016032=Reactome:REACT_6256, GO:0006816=PMID:8699119, GO:0070098=PMID:10201901, GO:0009986=PMID:10521508, GO:0023052=PMID:12032188, GO:0002407=PMID:16621978, GO:0003779=PMID:12421915, GO:0014808=PMID:19523456, GO:0015026=PMID:10469138, GO:0006968=PMID:10201901, GO:0007186=PMID:19523456, GO:0004435=PMID:8663314, GO:0005887=PMID:10393923, GO:0019048=GO_REF:0000037, GO:0070723=PMID:19523456, GO:0016493=PMID:11278962, GO:0009897=PMID:11278962, GO:0007166=PMID:8639485, GO:0005768=PMID:10679098} P51681 C-C chemokine receptor type 5 protein 20130413 {GO:0071791=IPI, GO:0005515=IPI, GO:0022415=TAS, GO:0019722=IDA, GO:0005886=TAS, GO:0030260=TAS, GO:0030818=IEA, GO:0007267=IDA, GO:0007204=TAS, GO:0019957=IPI, GO:0006955=IEA, GO:0005737=TAS, GO:0006954=IEA, GO:0006935=TAS, GO:0000165=IEP, GO:0004950=TAS, GO:0016032=TAS, GO:0006816=IDA, GO:0070098=TAS, GO:0009986=IDA, GO:0023052=IEP, GO:0002407=TAS, GO:0003779=IDA, GO:0014808=IDA, GO:0015026=TAS, GO:0006968=TAS, GO:0007186=IMP, GO:0004435=TAS, GO:0005887=TAS, GO:0019048=IEA, GO:0070723=IMP, GO:0016493=IDA, GO:0009897=IDA, GO:0007166=TAS, GO:0005768=IDA} G-protein coupled receptor signaling pathway, MAPK cascade, calcium ion transport, calcium-mediated signaling, cell surface receptor signaling pathway, cell-cell signaling, cellular defense response, chemokine-mediated signaling pathway, chemotaxis, dendritic cell chemotaxis, elevation of cytosolic calcium ion concentration, entry into host cell, immune response, inflammatory response, negative regulation of cAMP biosynthetic process, release of sequestered calcium ion into cytosol by sarcoplasmic reticulum, response to cholesterol, signaling, viral reproduction, viral reproductive process, virus-host interaction cell surface, cytoplasm, endosome, external side of plasma membrane, integral to plasma membrane, plasma membrane C-C chemokine binding, C-C chemokine receptor activity, actin binding, chemokine (C-C motif) ligand 5 binding, chemokine receptor activity, coreceptor activity, phosphatidylinositol phospholipase C activity, protein binding Human CCR6 GOC UniProtKB {GO:0070098=PMID:11001880, GO:0005886=Reactome:REACT_115591, GO:0030818=GO_REF:0000002, GO:0002407=PMID:16621978, GO:0006928=PMID:9186513, GO:0007204=GO_REF:0000002, GO:0019957=GO_REF:0000002, GO:0007165=PMID:9186513, GO:0006955=PMID:9223454, GO:0006968=PMID:10521347, GO:0006935=PMID:11001880, GO:0005887=PMID:9186513, GO:0045087=Reactome:REACT_6802, GO:0006959=PMID:11001880, GO:0004950=PMID:11001880, GO:0016493=GO_REF:0000002, GO:0004872=PMID:9186513} P51684 C-C chemokine receptor type 6 protein 20130413 {GO:0070098=TAS, GO:0005886=TAS, GO:0030818=IEA, GO:0002407=TAS, GO:0006928=TAS, GO:0007204=IEA, GO:0019957=IEA, GO:0007165=TAS, GO:0006955=TAS, GO:0006968=TAS, GO:0006935=TAS, GO:0005887=TAS, GO:0045087=TAS, GO:0006959=TAS, GO:0004950=TAS, GO:0016493=IEA, GO:0004872=TAS} cellular component movement, cellular defense response, chemokine-mediated signaling pathway, chemotaxis, dendritic cell chemotaxis, elevation of cytosolic calcium ion concentration, humoral immune response, immune response, innate immune response, negative regulation of cAMP biosynthetic process, signal transduction integral to plasma membrane, plasma membrane C-C chemokine binding, C-C chemokine receptor activity, chemokine receptor activity, receptor activity Human CCR7 GOC UniProtKB {GO:0002885=GO_REF:0000024, GO:0071731=PMID:16249377, GO:0046330=PMID:15778365, GO:0051491=PMID:15569314, GO:2000510=GO_REF:0000024, GO:2000147=PMID:15778365, GO:0031529=PMID:15569314, GO:0005622=PMID:21051556, GO:0032649=GO_REF:0000024, GO:0006935=GO_REF:0000019, GO:0043552=PMID:15778365, GO:0030838=PMID:11242036, GO:0034695=PMID:14592837, GO:0045860=PMID:14592837, GO:0032496=GO_REF:0000019, GO:0031274=PMID:11242036, GO:0070374=PMID:12729902, GO:0043123=PMID:15059845, GO:2000525=GO_REF:0000024, GO:2000526=GO_REF:0000024, GO:0051209=PMID:14592837, GO:0004930=PMID:16621978, GO:0032862=PMID:15778365, GO:2000522=GO_REF:0000024, GO:0045785=PMID:15569314, GO:0007186=PMID:16621978, GO:0090023=PMID:21051556, GO:0016493=GO_REF:0000024, GO:0050706=GO_REF:0000024, GO:0035758=PMID:9507024, GO:0009897=GO_REF:0000019, GO:0001954=PMID:15569314, GO:0035757=PMID:9507024, GO:0051897=PMID:15778365, GO:0005886=PMID:21051556, GO:0032735=GO_REF:0000024, GO:0097022=PMID:18379575, GO:0097029=GO_REF:0000024, GO:0007204=PMID:9153236, GO:0006955=GO_REF:0000019, GO:0006954=PMID:14592837, GO:0072610=GO_REF:0000024, GO:0038115=PMID:9507024, GO:0038116=PMID:9507024, GO:0002922=GO_REF:0000024, GO:2000547=GO_REF:0000024, GO:0002408=PMID:14592837, GO:0002407=PMID:15778365, GO:0050862=GO_REF:0000019, GO:0002606=GO_REF:0000024, GO:2000107=PMID:15059845, GO:0001768=PMID:12729902, GO:0045060=GO_REF:0000019, GO:0016021=GO_REF:0000037} P32248 C-C chemokine receptor type 7 protein 20130413 {GO:0002885=ISS, GO:0071731=IC, GO:0046330=IC, GO:0051491=IC, GO:2000510=ISS, GO:2000147=IC, GO:0031529=IC, GO:0005622=IDA, GO:0032649=ISS, GO:0006935=IEA, GO:0043552=IC, GO:0030838=IC, GO:0034695=IC, GO:0045860=IC, GO:0032496=IEA, GO:0031274=IC, GO:0070374=IC, GO:0043123=IC, GO:2000525=ISS, GO:2000526=ISS, GO:0051209=IC, GO:0004930=TAS, GO:0032862=IC, GO:2000522=ISS, GO:0045785=IC, GO:0007186=TAS, GO:0090023=IDA, GO:0016493=ISS, GO:0050706=ISS, GO:0035758=IPI, GO:0009897=IEA, GO:0001954=IC, GO:0035757=IPI, GO:0051897=IC, GO:0005886=IDA, GO:0032735=ISS, GO:0097022=TAS, GO:0097029=ISS, GO:0007204=TAS, GO:0006955=IEA, GO:0006954=NAS, GO:0072610=ISS, GO:0038115=IDA, GO:0038116=IDA, GO:0002922=ISS, GO:2000547=ISS, GO:0002408=IC, GO:0002407=IC, GO:0050862=IEA, GO:0002606=ISS, GO:2000107=IC, GO:0001768=IC, GO:0045060=IEA, GO:0016021=IEA} G-protein coupled receptor signaling pathway, activation of Rho GTPase activity, chemokine (C-C motif) ligand 19 signaling pathway, chemokine (C-C motif) ligand 21 signaling pathway, chemotaxis, dendritic cell chemotaxis, elevation of cytosolic calcium ion concentration, establishment of T cell polarity, immune response, inflammatory response, interleukin-12 secretion, lymphocyte migration into lymph node, mature dendritic cell differentiation, myeloid dendritic cell chemotaxis, negative regulation of leukocyte apoptotic process, negative thymic T cell selection, positive regulation of ERK1 and ERK2 cascade, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of JNK cascade, positive regulation of T cell costimulation, positive regulation of T cell receptor signaling pathway, positive regulation of actin filament polymerization, positive regulation of cell adhesion, positive regulation of cell motility, positive regulation of cell-matrix adhesion, positive regulation of dendritic cell antigen processing and presentation, positive regulation of dendritic cell chemotaxis, positive regulation of filopodium assembly, positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation, positive regulation of humoral immune response, positive regulation of hypersensitivity, positive regulation of immunological synapse formation, positive regulation of interleukin-12 production, positive regulation of neutrophil chemotaxis, positive regulation of phosphatidylinositol 3-kinase activity, positive regulation of protein kinase B signaling cascade, positive regulation of protein kinase activity, positive regulation of pseudopodium assembly, regulation of dendritic cell dendrite assembly, regulation of interferon-gamma production, regulation of interleukin-1 beta secretion, release of sequestered calcium ion into cytosol, response to lipopolysaccharide, response to nitric oxide, response to prostaglandin E stimulus, ruffle organization external side of plasma membrane, integral to membrane, intracellular, plasma membrane C-C chemokine receptor activity, G-protein coupled receptor activity, chemokine (C-C motif) ligand 19 binding, chemokine (C-C motif) ligand 21 binding Human CCR8 UniProtKB UniProtKB {GO:0070098=PMID:9417093, GO:0005886=Reactome:REACT_22289, GO:0015026=PMID:9417093, GO:0007204=GO_REF:0000002, GO:0019957=GO_REF:0000002, GO:0006955=GO_REF:0000002, GO:0006935=GO_REF:0000002, GO:0007186=PMID:8816377, GO:0005887=PMID:8816377, GO:0004950=PMID:9417093, GO:0016493=GO_REF:0000002, GO:0016021=GO_REF:0000038, GO:0007155=PMID:10910894} Q3KNR3 C-C chemokine receptor type 8 protein 20130413 {GO:0070098=TAS, GO:0005886=TAS, GO:0015026=TAS, GO:0007204=IEA, GO:0019957=IEA, GO:0006955=IEA, GO:0006935=IEA, GO:0007186=TAS, GO:0005887=TAS, GO:0004950=TAS, GO:0016493=IEA, GO:0016021=IEA, GO:0007155=TAS} G-protein coupled receptor signaling pathway, cell adhesion, chemokine-mediated signaling pathway, chemotaxis, elevation of cytosolic calcium ion concentration, immune response integral to membrane, integral to plasma membrane, plasma membrane C-C chemokine binding, C-C chemokine receptor activity, chemokine receptor activity, coreceptor activity Human UniProtKB-KW:KW-0812 CCR9 GOC UniProtKB {GO:0006968=PMID:10544196, GO:0006955=GO_REF:0000002, GO:0070098=PMID:10229797, GO:0005886=Reactome:REACT_22289, GO:0007186=PMID:10544196, GO:0006935=GO_REF:0000019, GO:0005887=PMID:10229797, GO:0004950=PMID:10229797, GO:0016493=GO_REF:0000019, GO:0007204=GO_REF:0000002, GO:0019957=GO_REF:0000002} P51686 C-C chemokine receptor type 9 protein 20130413 {GO:0006968=TAS, GO:0006955=IEA, GO:0070098=TAS, GO:0005886=TAS, GO:0007186=TAS, GO:0006935=IEA, GO:0005887=TAS, GO:0004950=TAS, GO:0016493=IEA, GO:0007204=IEA, GO:0019957=IEA} G-protein coupled receptor signaling pathway, cellular defense response, chemokine-mediated signaling pathway, chemotaxis, elevation of cytosolic calcium ion concentration, immune response integral to plasma membrane, plasma membrane C-C chemokine binding, C-C chemokine receptor activity, chemokine receptor activity Human CCRL1 GOC UniProtKB {GO:0006955=PMID:10706668, GO:0070098=PMID:10706668, GO:0005886=Reactome:REACT_21379, GO:0007186=PMID:10734104, GO:0006935=GO_REF:0000002, GO:0005887=PMID:10767544, GO:0004950=GO_REF:0000002, GO:0019956=GO_REF:0000002, GO:0005044=GO_REF:0000002} Q9NPB9 C-C chemokine receptor type 11 protein 20130413 {GO:0006955=TAS, GO:0070098=TAS, GO:0005886=TAS, GO:0007186=TAS, GO:0006935=IEA, GO:0005887=TAS, GO:0004950=IEA, GO:0019956=IEA, GO:0005044=IEA} G-protein coupled receptor signaling pathway, chemokine-mediated signaling pathway, chemotaxis, immune response integral to plasma membrane, plasma membrane chemokine binding, chemokine receptor activity, scavenger receptor activity Human CCS GOC UniProtKB {GO:0005515=PMID:20154138, GO:0051353=GO_REF:0000019, GO:0005507=PMID:9726962, GO:0006801=PMID:9295278, GO:0005743=GO_REF:0000033, GO:0005634=PMID:9726962, GO:0016532=GO_REF:0000033, GO:0035434=PMID:9726962, GO:0030001=GO_REF:0000002, GO:0046872=GO_REF:0000002, GO:0005829=GO_REF:0000033, GO:0015680=GO_REF:0000033, GO:0005737=PMID:9726962, GO:0005375=PMID:9726962, GO:0019430=GO_REF:0000033, GO:0008270=GO_REF:0000033, GO:0055114=GO_REF:0000002, GO:0004784=GO_REF:0000033} O14618 Copper chaperone for superoxide dismutase protein 20130413 {GO:0005515=IPI, GO:0051353=IEA, GO:0005507=TAS, GO:0006801=TAS, GO:0005743=IBA, GO:0005634=IDA, GO:0016532=IBA, GO:0035434=TAS, GO:0030001=IEA, GO:0046872=IEA, GO:0005829=IBA, GO:0015680=IBA, GO:0005737=IDA, GO:0005375=TAS, GO:0019430=IBA, GO:0008270=IBA, GO:0055114=IEA, GO:0004784=IBA} copper ion transmembrane transport, intracellular copper ion transport, metal ion transport, oxidation-reduction process, positive regulation of oxidoreductase activity, removal of superoxide radicals, superoxide metabolic process cytoplasm, cytosol, mitochondrial inner membrane, nucleus copper ion binding, copper ion transmembrane transporter activity, metal ion binding, protein binding, superoxide dismutase activity, superoxide dismutase copper chaperone activity, zinc ion binding Human CCT2 HPA UniProtKB {GO:0005515=PMID:22500027, GO:0005832=GO_REF:0000019, GO:0005874=PMID:21525035, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_16980, GO:0005737=GO_REF:0000052, GO:0006457=Reactome:REACT_17004, GO:0051084=Reactome:REACT_16952, GO:0051082=PMID:11532003, GO:0051131=PMID:20080638, GO:0044267=Reactome:REACT_17015} P78371 T-complex protein 1 subunit beta protein 20101115 {GO:0005515=IPI, GO:0005832=IEA, GO:0005874=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0005524=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0006457=TAS, GO:0051084=TAS, GO:0051082=NAS, GO:0051131=IMP, GO:0044267=TAS} 'de novo' posttranslational protein folding, cellular protein metabolic process, chaperone-mediated protein complex assembly, protein folding chaperonin-containing T-complex, cytoplasm, cytosol, microtubule, nucleolus, nucleus ATP binding, protein binding, unfolded protein binding Human CCT3 InterPro UniProtKB {GO:0005515=PMID:12620389, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005832=GO_REF:0000019, GO:0006457=GO_REF:0000002, GO:0005874=PMID:21525035, GO:0051084=Reactome:REACT_16952, GO:0051082=GO_REF:0000002, GO:0005856=PMID:8001976, GO:0044267=Reactome:REACT_17015, GO:0005524=GO_REF:0000002, GO:0005829=Reactome:REACT_16980} Q5SZX9 T-complex protein 1 subunit gamma protein 20130413 {GO:0005515=IPI, GO:0005737=IDA, GO:0005886=IDA, GO:0005832=IEA, GO:0006457=IEA, GO:0005874=IDA, GO:0051084=TAS, GO:0051082=IEA, GO:0005856=TAS, GO:0044267=TAS, GO:0005524=IEA, GO:0005829=TAS} 'de novo' posttranslational protein folding, cellular protein metabolic process, protein folding chaperonin-containing T-complex, cytoplasm, cytoskeleton, cytosol, microtubule, plasma membrane ATP binding, protein binding, unfolded protein binding Human InterPro:IPR002194|InterPro:IPR012719 CCT4 HPA UniProtKB {GO:0042470=GO_REF:0000039, GO:0005813=PMID:20080638, GO:0005832=GO_REF:0000019, GO:0005874=PMID:21525035, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_16980, GO:0005737=GO_REF:0000052, GO:0006457=Reactome:REACT_17004, GO:0051084=Reactome:REACT_16952, GO:0051082=GO_REF:0000002, GO:0044267=Reactome:REACT_17015} P50991 T-complex protein 1 subunit delta protein 20101115 {GO:0042470=IEA, GO:0005813=IDA, GO:0005832=IEA, GO:0005874=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0005524=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0006457=TAS, GO:0051084=TAS, GO:0051082=IEA, GO:0044267=TAS} 'de novo' posttranslational protein folding, cellular protein metabolic process, protein folding centrosome, chaperonin-containing T-complex, cytoplasm, cytosol, melanosome, microtubule, nucleolus, nucleus ATP binding, unfolded protein binding Human CCT5 HPA UniProtKB {GO:0005813=PMID:20080638, GO:0005737=GO_REF:0000052, GO:0005832=GO_REF:0000019, GO:0006457=Reactome:REACT_17004, GO:0005874=PMID:21525035, GO:0005730=GO_REF:0000052, GO:0051084=Reactome:REACT_16952, GO:0051082=GO_REF:0000002, GO:0009615=PMID:16548883, GO:0044267=Reactome:REACT_17015, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_16980} P48643 T-complex protein 1 subunit epsilon protein 20101115 {GO:0005813=IDA, GO:0005737=IDA, GO:0005832=IEA, GO:0006457=TAS, GO:0005874=IDA, GO:0005730=IDA, GO:0051084=TAS, GO:0051082=IEA, GO:0009615=IEP, GO:0044267=TAS, GO:0005524=IEA, GO:0005829=TAS} 'de novo' posttranslational protein folding, cellular protein metabolic process, protein folding, response to virus centrosome, chaperonin-containing T-complex, cytoplasm, cytosol, microtubule, nucleolus ATP binding, unfolded protein binding Human CCT6A Reactome UniProtKB {GO:0005737=PMID:8034610, GO:0005832=GO_REF:0000019, GO:0006457=Reactome:REACT_17004, GO:0005874=PMID:21525035, GO:0051084=Reactome:REACT_16952, GO:0051082=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_16980} P40227 T-complex protein 1 subunit zeta protein 20130213 {GO:0005737=TAS, GO:0005832=IEA, GO:0006457=TAS, GO:0005874=IDA, GO:0051084=TAS, GO:0051082=IEA, GO:0044267=TAS, GO:0005524=IEA, GO:0005829=TAS} 'de novo' posttranslational protein folding, cellular protein metabolic process, protein folding chaperonin-containing T-complex, cytoplasm, cytosol, microtubule ATP binding, unfolded protein binding Human CCT6B GOC UniProtKB {GO:0005737=GO_REF:0000039, GO:0006457=GO_REF:0000002, GO:0008565=PMID:8812458, GO:0007283=PMID:8812458, GO:0051082=GO_REF:0000002, GO:0015031=PMID:8812458, GO:0051131=PMID:8812458, GO:0005524=GO_REF:0000037} Q92526 T-complex protein 1 subunit zeta-2 protein 20130413 {GO:0005737=IEA, GO:0006457=IEA, GO:0008565=TAS, GO:0007283=TAS, GO:0051082=IEA, GO:0015031=TAS, GO:0051131=TAS, GO:0005524=IEA} chaperone-mediated protein complex assembly, protein folding, protein transport, spermatogenesis cytoplasm ATP binding, protein transporter activity, unfolded protein binding Human CCT7 HPA UniProtKB {GO:0005739=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0005832=GO_REF:0000019, GO:0006457=Reactome:REACT_17004, GO:0005874=PMID:21525035, GO:0051084=Reactome:REACT_16952, GO:0051082=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_16980, GO:0042802=GO_REF:0000019} Q99832 T-complex protein 1 subunit eta protein 20080818 {GO:0005739=IEA, GO:0005737=IDA, GO:0005832=IEA, GO:0006457=TAS, GO:0005874=IDA, GO:0051084=TAS, GO:0051082=IEA, GO:0044267=TAS, GO:0005524=IEA, GO:0005829=TAS, GO:0042802=IEA} 'de novo' posttranslational protein folding, cellular protein metabolic process, protein folding chaperonin-containing T-complex, cytoplasm, cytosol, microtubule, mitochondrion ATP binding, identical protein binding, unfolded protein binding Human CCT8 HPA UniProtKB {GO:0005813=PMID:20080638, GO:0005737=GO_REF:0000052, GO:0042623=PMID:7890169, GO:0016235=GO_REF:0000052, GO:0006457=Reactome:REACT_17004, GO:0005874=PMID:21525035, GO:0051084=Reactome:REACT_16952, GO:0045111=GO_REF:0000052, GO:0051082=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_16980} P50990 T-complex protein 1 subunit theta protein 20101115 {GO:0005813=IDA, GO:0005737=IDA, GO:0042623=TAS, GO:0016235=IDA, GO:0006457=TAS, GO:0005874=IDA, GO:0051084=TAS, GO:0045111=IDA, GO:0051082=IEA, GO:0044267=TAS, GO:0005524=IEA, GO:0005829=TAS} 'de novo' posttranslational protein folding, cellular protein metabolic process, protein folding aggresome, centrosome, cytoplasm, cytosol, intermediate filament cytoskeleton, microtubule ATP binding, ATPase activity, coupled, unfolded protein binding Human CCZ1 UniProtKB UniProtKB {GO:0005765=GO_REF:0000039} P86791 Vacuolar fusion protein CCZ1 homolog protein 20130413 {GO:0005765=IEA} lysosomal membrane Human UniProtKB-SubCell:SL-0157 CCZ1B UniProtKB UniProtKB {GO:0005765=GO_REF:0000039} P86790 Vacuolar fusion protein CCZ1 homolog B protein 20130413 {GO:0005765=IEA} lysosomal membrane Human UniProtKB-SubCell:SL-0157 CD101 PINC UniProtKB {GO:0005886=PMID:7722300, GO:0016812=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007166=PMID:7722300} Q93033 Immunoglobulin superfamily member 2 protein 20030904 {GO:0005886=TAS, GO:0016812=IEA, GO:0016021=IEA, GO:0007166=TAS} cell surface receptor signaling pathway integral to membrane, plasma membrane hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides Human CD109 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0004867=GO_REF:0000037, GO:0031225=GO_REF:0000037, GO:0005615=GO_REF:0000002} Q6YHK3 CD109 antigen protein 20130413 {GO:0005886=IEA, GO:0004867=IEA, GO:0031225=IEA, GO:0005615=IEA} anchored to membrane, extracellular space, plasma membrane serine-type endopeptidase inhibitor activity Human UniProtKB-SubCell:SL-0039 CD14 BHF-UCL UniProtKB {GO:0006909=PMID:9548256, GO:0034142=Reactome:REACT_6894, GO:0009408=GO_REF:0000019, GO:0005886=Reactome:REACT_150423, GO:0070891=PMID:12594207, GO:0007249=Reactome:REACT_25351, GO:0031225=GO_REF:0000037, GO:0050715=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0045807=GO_REF:0000019, GO:0002756=Reactome:REACT_6809, GO:0006954=GO_REF:0000019, GO:0002755=Reactome:REACT_6788, GO:0032496=GO_REF:0000019, GO:0034138=Reactome:REACT_6783, GO:0038124=Reactome:REACT_8006, GO:0016019=PMID:8798531, GO:0038123=Reactome:REACT_8005, GO:0009986=GO_REF:0000019, GO:0032760=PMID:12594207, GO:0001847=PMID:2402637, GO:0034134=Reactome:REACT_7980, GO:0006915=PMID:9548256, GO:0005576=Reactome:REACT_150423, GO:0002224=Reactome:REACT_6966, GO:0001530=PMID:12594207, GO:0071223=PMID:12594207, GO:0071222=PMID:12594207, GO:0045087=Reactome:REACT_6802, GO:0035666=Reactome:REACT_25281, GO:0045121=GO_REF:0000019, GO:0007166=PMID:8798531, GO:0010008=Reactome:REACT_150447} P08571 Monocyte differentiation antigen CD14 protein 20080707 {GO:0006909=TAS, GO:0034142=TAS, GO:0009408=IEA, GO:0005886=TAS, GO:0070891=IDA, GO:0007249=TAS, GO:0031225=IEA, GO:0050715=IEA, GO:0005615=IEA, GO:0045807=IEA, GO:0002756=TAS, GO:0006954=IEA, GO:0002755=TAS, GO:0032496=IEA, GO:0034138=TAS, GO:0038124=TAS, GO:0016019=TAS, GO:0038123=TAS, GO:0009986=IEA, GO:0032760=IDA, GO:0001847=TAS, GO:0034134=TAS, GO:0006915=TAS, GO:0005576=TAS, GO:0002224=TAS, GO:0001530=IDA, GO:0071223=IDA, GO:0071222=IDA, GO:0045087=TAS, GO:0035666=TAS, GO:0045121=IEA, GO:0007166=TAS, GO:0010008=TAS} I-kappaB kinase/NF-kappaB cascade, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, apoptotic process, cell surface receptor signaling pathway, cellular response to lipopolysaccharide, cellular response to lipoteichoic acid, inflammatory response, innate immune response, phagocytosis, positive regulation of cytokine secretion, positive regulation of endocytosis, positive regulation of tumor necrosis factor production, response to heat, response to lipopolysaccharide, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway anchored to membrane, cell surface, endosome membrane, extracellular region, extracellular space, membrane raft, plasma membrane lipopolysaccharide binding, lipoteichoic acid binding, opsonin receptor activity, peptidoglycan receptor activity Human CD151 Reactome UniProtKB {GO:0005515=PMID:14676841, GO:0005886=Reactome:REACT_150217, GO:0016020=PMID:8627808, GO:0042098=GO_REF:0000019, GO:0016477=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0005887=PMID:8627808, GO:0034329=Reactome:REACT_20676, GO:0031581=Reactome:REACT_20537, GO:0016021=GO_REF:0000038, GO:0007155=PMID:9602068, GO:0005829=Reactome:REACT_20665} P48509 CD151 antigen protein 20130213 {GO:0005515=IPI, GO:0005886=TAS, GO:0016020=TAS, GO:0042098=IEA, GO:0016477=IEA, GO:0030198=TAS, GO:0005887=TAS, GO:0034329=TAS, GO:0031581=TAS, GO:0016021=IEA, GO:0007155=NAS, GO:0005829=TAS} T cell proliferation, cell adhesion, cell junction assembly, cell migration, extracellular matrix organization, hemidesmosome assembly cytosol, integral to membrane, integral to plasma membrane, membrane, plasma membrane protein binding Human CD160 Reactome UniProtKB {GO:0006968=PMID:9743336, GO:0005886=Reactome:REACT_11106, GO:0008283=PMID:9973372, GO:0050776=Reactome:REACT_11152, GO:0005102=PMID:9973372, GO:0004872=PMID:9973372, GO:0046658=PMID:9973372, GO:0007166=PMID:9973372, GO:0032393=PMID:15494480} O95971 CD160 antigen protein 20070516 {GO:0006968=TAS, GO:0005886=TAS, GO:0008283=TAS, GO:0050776=TAS, GO:0005102=IDA, GO:0004872=TAS, GO:0046658=IDA, GO:0007166=TAS, GO:0032393=IDA} cell proliferation, cell surface receptor signaling pathway, cellular defense response, regulation of immune response anchored to plasma membrane, plasma membrane MHC class I receptor activity, receptor activity, receptor binding Human CD163 Reactome UniProtKB {GO:0030666=Reactome:REACT_160193, GO:0005515=PMID:15479433, GO:0005886=Reactome:REACT_160225, GO:0016020=GO_REF:0000002, GO:0005887=PMID:8370408, GO:0005576=GO_REF:0000029, GO:0006953=GO_REF:0000037, GO:0005044=PMID:8370408} Q86VB7 Scavenger receptor cysteine-rich type 1 protein M130 protein 20120506 {GO:0030666=TAS, GO:0005515=IPI, GO:0005886=TAS, GO:0016020=IEA, GO:0005887=TAS, GO:0005576=NAS, GO:0006953=IEA, GO:0005044=NAS} acute-phase response endocytic vesicle membrane, extracellular region, integral to plasma membrane, membrane, plasma membrane protein binding, scavenger receptor activity Human CD164 PINC UniProtKB {GO:0030097=PMID:11027692, GO:0005515=PMID:17077324, GO:0008285=PMID:10878358, GO:0005886=PMID:10491205, GO:0007275=PMID:9680353, GO:0005576=GO_REF:0000039, GO:0005765=GO_REF:0000039, GO:0005764=PMID:11027692, GO:0007165=PMID:9763543, GO:0007162=PMID:10878358, GO:0006955=PMID:9763543, GO:0007517=GO_REF:0000037, GO:0005887=PMID:11027692, GO:0007155=PMID:10491205, GO:0007157=PMID:10491205, GO:0010008=GO_REF:0000039, GO:0005768=PMID:11027692} Q04900 Sialomucin core protein 24 protein 20030904 {GO:0030097=NAS, GO:0005515=IPI, GO:0008285=NAS, GO:0005886=IDA, GO:0007275=TAS, GO:0005576=IEA, GO:0005765=IEA, GO:0005764=IDA, GO:0007165=TAS, GO:0007162=NAS, GO:0006955=TAS, GO:0007517=IEA, GO:0005887=NAS, GO:0007155=IDA, GO:0007157=IDA, GO:0010008=IEA, GO:0005768=IDA} cell adhesion, hemopoiesis, heterophilic cell-cell adhesion, immune response, multicellular organismal development, muscle organ development, negative regulation of cell adhesion, negative regulation of cell proliferation, signal transduction endosome, endosome membrane, extracellular region, integral to plasma membrane, lysosomal membrane, lysosome, plasma membrane protein binding Human CD177 Reactome UniProtKB {GO:0005886=Reactome:REACT_12006, GO:0007596=Reactome:REACT_604, GO:0031225=GO_REF:0000037, GO:0050900=Reactome:REACT_12051} Q8N6Q3 CD177 antigen protein 20071111 {GO:0005886=TAS, GO:0007596=TAS, GO:0031225=IEA, GO:0050900=TAS} blood coagulation, leukocyte migration anchored to membrane, plasma membrane Human CD180 MGI UniProtKB {GO:0006954=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0045087=GO_REF:0000037, GO:0031666=PMID:10880523, GO:0016021=GO_REF:0000037} Q99467 CD180 antigen protein 20130227 {GO:0006954=IEA, GO:0005886=IEA, GO:0045087=IEA, GO:0031666=IGI, GO:0016021=IEA} inflammatory response, innate immune response, positive regulation of lipopolysaccharide-mediated signaling pathway integral to membrane, plasma membrane Human UniProtKB:O95711 CD19 Reactome UniProtKB {GO:0050853=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0005886=Reactome:REACT_147854, GO:0048015=Reactome:REACT_12464, GO:0006968=PMID:1373518, GO:0007173=Reactome:REACT_9417, GO:0005887=PMID:2472450, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0050776=Reactome:REACT_11152, GO:0005057=PMID:1373518, GO:0009897=PMID:20660734, GO:0007166=PMID:1714482} P15391 B-lymphocyte antigen CD19 protein 20120127 {GO:0050853=IEA, GO:0048011=TAS, GO:0005886=TAS, GO:0048015=TAS, GO:0006968=TAS, GO:0007173=TAS, GO:0005887=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0050776=TAS, GO:0005057=TAS, GO:0009897=IDA, GO:0007166=TAS} B cell receptor signaling pathway, cell surface receptor signaling pathway, cellular defense response, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, regulation of immune response external side of plasma membrane, integral to plasma membrane, plasma membrane receptor signaling protein activity Human CD1A IntAct UniProtKB {GO:0005515=PMID:15723809, GO:0006955=PMID:2447586, GO:0005887=PMID:2447586, GO:0019882=GO_REF:0000002, GO:0042612=GO_REF:0000002, GO:0010008=GO_REF:0000039} P06126 T-cell surface glycoprotein CD1a protein 20130415 {GO:0005515=IPI, GO:0006955=NAS, GO:0005887=NAS, GO:0019882=IEA, GO:0042612=IEA, GO:0010008=IEA} antigen processing and presentation, immune response MHC class I protein complex, endosome membrane, integral to plasma membrane protein binding Human UniProtKB:P61769 CD1B IntAct UniProtKB {GO:0005515=PMID:14764708, GO:0006955=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0019882=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005765=GO_REF:0000039, GO:0010008=GO_REF:0000039} P29016 T-cell surface glycoprotein CD1b protein 20130415 {GO:0005515=IPI, GO:0006955=IEA, GO:0005886=IEA, GO:0016020=IEA, GO:0019882=IEA, GO:0016021=IEA, GO:0005765=IEA, GO:0010008=IEA} antigen processing and presentation, immune response endosome membrane, integral to membrane, lysosomal membrane, membrane, plasma membrane protein binding Human UniProtKB:P61769 CD1C PINC UniProtKB {GO:0071723=PMID:21167756, GO:0006955=GO_REF:0000002, GO:0051861=PMID:21167756, GO:0005886=PMID:2447586, GO:0016020=GO_REF:0000002, GO:0005887=PMID:1702817, GO:0019882=GO_REF:0000002, GO:0030884=PMID:21167756, GO:0030883=PMID:21167756, GO:0002286=PMID:21167756, GO:0010008=GO_REF:0000039} P29017 T-cell surface glycoprotein CD1c protein 20030904 {GO:0071723=IDA, GO:0006955=IEA, GO:0051861=IDA, GO:0005886=TAS, GO:0016020=IEA, GO:0005887=TAS, GO:0019882=IEA, GO:0030884=IDA, GO:0030883=IDA, GO:0002286=IDA, GO:0010008=IEA} T cell activation involved in immune response, antigen processing and presentation, immune response endosome membrane, integral to plasma membrane, membrane, plasma membrane endogenous lipid antigen binding, exogenous lipid antigen binding, glycolipid binding, lipopeptide binding Human CD1D BHF-UCL UniProtKB {GO:0030882=PMID:19124746, GO:0030881=PMID:14500461, GO:0043499=PMID:19124746, GO:0009986=PMID:19124746, GO:0030884=PMID:10523605, GO:0005765=GO_REF:0000039, GO:0045058=PMID:14500461, GO:0042393=PMID:20363964, GO:0005737=PMID:19124746, GO:0045089=PMID:14500461, GO:0005887=PMID:11315191, GO:0019048=GO_REF:0000037, GO:0045087=GO_REF:0000037, GO:0042102=PMID:19124746, GO:0048006=PMID:10523605, GO:0034113=PMID:19124746, GO:0004872=PMID:11315191, GO:0050839=PMID:19124746, GO:0016045=PMID:14500461, GO:0010008=GO_REF:0000039} P15813 Antigen-presenting glycoprotein CD1d protein 20111125 {GO:0030882=IDA, GO:0030881=TAS, GO:0043499=IDA, GO:0009986=IDA, GO:0030884=IDA, GO:0005765=IEA, GO:0045058=TAS, GO:0042393=IPI, GO:0005737=IDA, GO:0045089=TAS, GO:0005887=TAS, GO:0019048=IEA, GO:0045087=IEA, GO:0042102=IDA, GO:0048006=IDA, GO:0034113=TAS, GO:0004872=IC, GO:0050839=IPI, GO:0016045=TAS, GO:0010008=IEA} T cell selection, antigen processing and presentation, endogenous lipid antigen via MHC class Ib, detection of bacterium, heterotypic cell-cell adhesion, innate immune response, positive regulation of T cell proliferation, positive regulation of innate immune response, virus-host interaction cell surface, cytoplasm, endosome membrane, integral to plasma membrane, lysosomal membrane beta-2-microglobulin binding, cell adhesion molecule binding, eukaryotic cell surface binding, exogenous lipid antigen binding, histone binding, lipid antigen binding, receptor activity Human CD1E UniProtKB UniProtKB {GO:0006955=PMID:2467814, GO:0000139=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0005887=PMID:2467814, GO:0005770=GO_REF:0000039, GO:0019882=GO_REF:0000002, GO:0005769=GO_REF:0000039, GO:0043202=GO_REF:0000039} P15812 T-cell surface glycoprotein CD1e, membrane-associated protein 20010912 {GO:0006955=NAS, GO:0000139=IEA, GO:0016020=IEA, GO:0005887=NAS, GO:0005770=IEA, GO:0019882=IEA, GO:0005769=IEA, GO:0043202=IEA} antigen processing and presentation, immune response Golgi membrane, early endosome, integral to plasma membrane, late endosome, lysosomal lumen, membrane Human CD2 InterPro UniProtKB {GO:0005515=PMID:1970422, GO:0043499=GO_REF:0000019, GO:0005886=Reactome:REACT_12031, GO:0005576=GO_REF:0000019, GO:0030887=PMID:12714509, GO:0006917=PMID:9270771, GO:0050900=Reactome:REACT_12051, GO:0042803=GO_REF:0000019, GO:0016337=PMID:7544493, GO:0042110=PMID:2471997, GO:0030101=PMID:12714509, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:7544493, GO:0045580=PMID:11544295, GO:0009898=GO_REF:0000019, GO:0001766=PMID:11376005, GO:0004872=GO_REF:0000002, GO:0016021=GO_REF:0000002, GO:0046658=GO_REF:0000019, GO:0009897=PMID:21460847, GO:0007166=PMID:10575274} Q5JVN7 T-cell surface antigen CD2 protein 20130413 {GO:0005515=IPI, GO:0043499=IEA, GO:0005886=TAS, GO:0005576=IEA, GO:0030887=NAS, GO:0006917=TAS, GO:0050900=TAS, GO:0042803=IEA, GO:0016337=NAS, GO:0042110=TAS, GO:0030101=NAS, GO:0007596=TAS, GO:0005887=NAS, GO:0045580=NAS, GO:0009898=IEA, GO:0001766=TAS, GO:0004872=IEA, GO:0016021=IEA, GO:0046658=IEA, GO:0009897=IDA, GO:0007166=TAS} T cell activation, blood coagulation, cell surface receptor signaling pathway, cell-cell adhesion, induction of apoptosis, leukocyte migration, membrane raft polarization, natural killer cell activation, positive regulation of myeloid dendritic cell activation, regulation of T cell differentiation anchored to plasma membrane, external side of plasma membrane, extracellular region, integral to membrane, integral to plasma membrane, internal side of plasma membrane, plasma membrane eukaryotic cell surface binding, protein binding, protein homodimerization activity, receptor activity Human InterPro:IPR015631 CD200 IntAct UniProtKB {GO:0005515=PMID:21982860, GO:0005886=Reactome:REACT_11188, GO:0005887=PMID:3032785, GO:0050776=Reactome:REACT_11152} P41217 OX-2 membrane glycoprotein protein 20130415 {GO:0005515=IPI, GO:0005886=TAS, GO:0005887=TAS, GO:0050776=TAS} regulation of immune response integral to plasma membrane, plasma membrane protein binding Human UniProtKB:Q8TD46 CD200R1 IntAct UniProtKB {GO:0005515=PMID:21982860, GO:0005886=Reactome:REACT_11188, GO:0016020=GO_REF:0000038, GO:0019048=GO_REF:0000037, GO:0050776=Reactome:REACT_11152, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q8TD46 Cell surface glycoprotein CD200 receptor 1 protein 20130415 {GO:0005515=IPI, GO:0005886=TAS, GO:0016020=IEA, GO:0019048=IEA, GO:0050776=TAS, GO:0005576=IEA, GO:0016021=IEA} regulation of immune response, virus-host interaction extracellular region, integral to membrane, membrane, plasma membrane protein binding Human UniProtKB:P41217 CD209 MGI UniProtKB {GO:0019062=PMID:11337487, GO:0005886=GO_REF:0000039, GO:0009988=PMID:11337487, GO:0046790=PMID:11337487, GO:0005576=GO_REF:0000039, GO:0046795=PMID:11337487, GO:0019079=PMID:11337487, GO:0005537=PMID:1518869, GO:0046872=GO_REF:0000037, GO:0006897=GO_REF:0000037, GO:0035556=PMID:11337487, GO:0046968=PMID:11337487, GO:0005737=PMID:11337487, GO:0016020=PMID:1518869, GO:0019882=PMID:11337487, GO:0019048=PMID:11337487, GO:0045087=GO_REF:0000037, GO:0042605=PMID:11337487, GO:0042129=PMID:12456590, GO:0007159=PMID:11337487, GO:0030246=PMID:11337487, GO:0016021=GO_REF:0000037, GO:0007157=PMID:1518869} Q9NNX6 CD209 antigen protein 20120402 {GO:0019062=TAS, GO:0005886=IEA, GO:0009988=TAS, GO:0046790=TAS, GO:0005576=IEA, GO:0046795=TAS, GO:0019079=NAS, GO:0005537=TAS, GO:0046872=IEA, GO:0006897=IEA, GO:0035556=NAS, GO:0046968=NAS, GO:0005737=NAS, GO:0016020=TAS, GO:0019882=NAS, GO:0019048=TAS, GO:0045087=IEA, GO:0042605=NAS, GO:0042129=IDA, GO:0007159=NAS, GO:0030246=NAS, GO:0016021=IEA, GO:0007157=TAS} antigen processing and presentation, cell-cell recognition, endocytosis, heterophilic cell-cell adhesion, innate immune response, intracellular signal transduction, intracellular virion transport, leukocyte cell-cell adhesion, peptide antigen transport, regulation of T cell proliferation, viral attachment to host cell, viral genome replication, virus-host interaction cytoplasm, extracellular region, integral to membrane, membrane, plasma membrane carbohydrate binding, mannose binding, metal ion binding, peptide antigen binding, virion binding Human CD22 IntAct UniProtKB {GO:0005515=PMID:8647200, GO:0005887=GO_REF:0000019, GO:0007155=GO_REF:0000037, GO:0009897=GO_REF:0000019} P20273 B-cell receptor CD22 protein 20130415 {GO:0005515=IPI, GO:0005887=IEA, GO:0007155=IEA, GO:0009897=IEA} cell adhesion external side of plasma membrane, integral to plasma membrane protein binding Human UniProtKB:P43405 CD226 BHF-UCL UniProtKB {GO:0005515=PMID:21982860, GO:0008037=PMID:16304049, GO:0009986=PMID:16831868, GO:0005886=Reactome:REACT_11239, GO:0019901=PMID:16831868, GO:0033005=PMID:16831868, GO:0001816=GO_REF:0000019, GO:0007165=PMID:8673704, GO:0005178=PMID:16831868, GO:0005887=PMID:8673704, GO:0050776=Reactome:REACT_11152, GO:0045954=PMID:16304049, GO:0002860=PMID:12913096, GO:0045121=PMID:16831868, GO:0007155=GO_REF:0000037, GO:0050839=PMID:12913096, GO:0060369=PMID:16831868, GO:0002891=PMID:16831868} Q15762 CD226 antigen protein 20081127 {GO:0005515=IPI, GO:0008037=TAS, GO:0009986=IDA, GO:0005886=TAS, GO:0019901=IPI, GO:0033005=IDA, GO:0001816=IEA, GO:0007165=TAS, GO:0005178=IPI, GO:0005887=TAS, GO:0050776=TAS, GO:0045954=IMP, GO:0002860=IMP, GO:0045121=TAS, GO:0007155=IEA, GO:0050839=IPI, GO:0060369=IDA, GO:0002891=IDA} cell adhesion, cell recognition, cytokine production, positive regulation of Fc receptor mediated stimulatory signaling pathway, positive regulation of immunoglobulin mediated immune response, positive regulation of mast cell activation, positive regulation of natural killer cell mediated cytotoxicity, positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, regulation of immune response, signal transduction cell surface, integral to plasma membrane, membrane raft, plasma membrane cell adhesion molecule binding, integrin binding, protein binding, protein kinase binding Human UniProtKB:Q92692 CD24 GOC UniProtKB {GO:0005515=PMID:22731636, GO:0045730=PMID:8223854, GO:0072112=PMID:19092120, GO:0043627=PMID:10037815, GO:0005886=GO_REF:0000039, GO:0061098=PMID:11313396, GO:0031295=PMID:11272271, GO:0002237=PMID:15493995, GO:0031225=GO_REF:0000037, GO:0032597=PMID:11313396, GO:0007204=PMID:8223854, GO:0032913=PMID:16930538, GO:0072139=PMID:19092120, GO:0042104=PMID:11272271, GO:0016337=PMID:15633604, GO:0030296=PMID:11313396, GO:0030856=PMID:16930538, GO:0007411=Reactome:REACT_18266, GO:0043406=PMID:12496407, GO:0032600=GO_REF:0000024, GO:0043408=PMID:11313396, GO:0004871=PMID:8213086, GO:0016055=PMID:16532032, GO:0001775=PMID:8223854, GO:0042632=PMID:16390867, GO:0001666=PMID:15174142, GO:0009986=PMID:16532032, GO:0019901=PMID:8753773, GO:0097193=PMID:11313396, GO:2000768=PMID:16885410, GO:0042325=PMID:11313396, GO:0001959=PMID:16390867, GO:0002768=PMID:11313396, GO:0016477=PMID:16390867, GO:0016020=PMID:10037815, GO:0045121=PMID:11313396} P25063 Signal transducer CD24 protein 20130413 {GO:0005515=IPI, GO:0045730=IDA, GO:0072112=IMP, GO:0043627=IEP, GO:0005886=IEA, GO:0061098=IDA, GO:0031295=IDA, GO:0002237=ISS, GO:0031225=IEA, GO:0032597=IDA, GO:0007204=IDA, GO:0032913=IMP, GO:0072139=IMP, GO:0042104=IDA, GO:0016337=NAS, GO:0030296=IDA, GO:0030856=NAS, GO:0007411=TAS, GO:0043406=IDA, GO:0032600=ISS, GO:0043408=IDA, GO:0004871=NAS, GO:0016055=NAS, GO:0001775=IDA, GO:0042632=ISS, GO:0001666=IEP, GO:0009986=IDA, GO:0019901=IPI, GO:0097193=NAS, GO:2000768=IMP, GO:0042325=IDA, GO:0001959=ISS, GO:0002768=IC, GO:0016477=ISS, GO:0016020=IDA, GO:0045121=IDA} B cell receptor transport into membrane raft, T cell costimulation, Wnt receptor signaling pathway, axon guidance, cell activation, cell migration, cell-cell adhesion, chemokine receptor transport out of membrane raft, cholesterol homeostasis, elevation of cytosolic calcium ion concentration, glomerular parietal epithelial cell differentiation, glomerular visceral epithelial cell differentiation, immune response-regulating cell surface receptor signaling pathway, intrinsic apoptotic signaling pathway, negative regulation of transforming growth factor beta3 production, positive regulation of MAP kinase activity, positive regulation of activated T cell proliferation, positive regulation of nephron tubule epithelial cell differentiation, positive regulation of protein tyrosine kinase activity, regulation of MAPK cascade, regulation of cytokine-mediated signaling pathway, regulation of epithelial cell differentiation, regulation of phosphorylation, respiratory burst, response to estrogen stimulus, response to hypoxia, response to molecule of bacterial origin anchored to membrane, cell surface, membrane, membrane raft, plasma membrane protein binding, protein kinase binding, protein tyrosine kinase activator activity, signal transducer activity Human CD244 IntAct UniProtKB {GO:0005515=PMID:18296487, GO:0007165=PMID:10358138, GO:0005886=Reactome:REACT_12018, GO:0007596=Reactome:REACT_604, GO:0004872=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0050900=Reactome:REACT_12051, GO:0009897=PMID:17213291} Q9BZW8 Natural killer cell receptor 2B4 protein 20130415 {GO:0005515=IPI, GO:0007165=TAS, GO:0005886=TAS, GO:0007596=TAS, GO:0004872=IEA, GO:0016021=IEA, GO:0050900=TAS, GO:0009897=IDA} blood coagulation, leukocyte migration, signal transduction external side of plasma membrane, integral to membrane, plasma membrane protein binding, receptor activity Human UniProtKB:P09326 CD247 IntAct UniProtKB {GO:0005515=PMID:16461343, GO:0050852=Reactome:REACT_12526, GO:0005886=Reactome:REACT_160316, GO:0031295=Reactome:REACT_19344, GO:0042803=PMID:12110186, GO:0042802=PMID:17055436, GO:0050690=Reactome:REACT_11068, GO:0042105=GO_REF:0000019, GO:0005737=PMID:11390434, GO:0019048=GO_REF:0000037, GO:0042101=PMID:8176201, GO:0045087=Reactome:REACT_6802, GO:0050776=Reactome:REACT_11152, GO:0016032=Reactome:REACT_6185, GO:0016021=GO_REF:0000037, GO:0038096=Reactome:REACT_160123, GO:0004888=GO_REF:0000002} P20963 T-cell surface glycoprotein CD3 zeta chain protein 20130415 {GO:0005515=IPI, GO:0050852=TAS, GO:0005886=TAS, GO:0031295=TAS, GO:0042803=NAS, GO:0042802=IPI, GO:0050690=TAS, GO:0042105=IEA, GO:0005737=IDA, GO:0019048=IEA, GO:0042101=IDA, GO:0045087=TAS, GO:0050776=TAS, GO:0016032=TAS, GO:0016021=IEA, GO:0038096=TAS, GO:0004888=IEA} Fc-gamma receptor signaling pathway involved in phagocytosis, T cell costimulation, T cell receptor signaling pathway, innate immune response, regulation of defense response to virus by virus, regulation of immune response, viral reproduction, virus-host interaction T cell receptor complex, alpha-beta T cell receptor complex, cytoplasm, integral to membrane, plasma membrane identical protein binding, protein binding, protein homodimerization activity, transmembrane signaling receptor activity Human UniProtKB:P20963 CD248 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0005578=PMID:10947988, GO:0030246=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q9HCU0 Endosialin protein 20111208 {GO:0003674=ND, GO:0008150=ND, GO:0005737=IEA, GO:0005509=IEA, GO:0005578=TAS, GO:0030246=IEA, GO:0016021=IEA} biological_process cytoplasm, integral to membrane, proteinaceous extracellular matrix calcium ion binding, carbohydrate binding, molecular_function Human CD27 GOC UniProtKB {GO:0005515=PMID:16683188, GO:0043066=PMID:12324477, GO:0016064=PMID:14556986, GO:0045471=GO_REF:0000019, GO:0045579=PMID:10809378, GO:0046330=GO_REF:0000024, GO:0005576=PMID:12624711, GO:0006917=PMID:9177220, GO:0008588=PMID:12324477, GO:0005887=PMID:12324477, GO:0043154=PMID:12324477, GO:0043027=PMID:12324477, GO:0007166=PMID:14556986, GO:0009897=GO_REF:0000019, GO:0004888=PMID:14556986} P26842 CD27 antigen protein 20130413 {GO:0005515=IPI, GO:0043066=IDA, GO:0016064=NAS, GO:0045471=IEA, GO:0045579=NAS, GO:0046330=ISS, GO:0005576=NAS, GO:0006917=IDA, GO:0008588=NAS, GO:0005887=NAS, GO:0043154=IDA, GO:0043027=IDA, GO:0007166=NAS, GO:0009897=IEA, GO:0004888=NAS} cell surface receptor signaling pathway, immunoglobulin mediated immune response, induction of apoptosis, negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of B cell differentiation, positive regulation of JNK cascade, release of cytoplasmic sequestered NF-kappaB, response to ethanol external side of plasma membrane, extracellular region, integral to plasma membrane cysteine-type endopeptidase inhibitor activity involved in apoptotic process, protein binding, transmembrane signaling receptor activity Human CD274 IntAct UniProtKB {GO:0005515=PMID:21982860, GO:0007165=PMID:10581077, GO:2001181=PMID:10581077, GO:0006955=PMID:10581077, GO:0005886=Reactome:REACT_19312, GO:0031295=Reactome:REACT_19344, GO:0042102=PMID:10581077, GO:0016021=GO_REF:0000037, GO:0007166=PMID:10581077, GO:0009897=GO_REF:0000019, GO:0012505=GO_REF:0000039, GO:0042130=GO_REF:0000019} Q9NZQ7 Programmed cell death 1 ligand 1 protein 20130415 {GO:0005515=IPI, GO:0007165=IDA, GO:2001181=IDA, GO:0006955=IDA, GO:0005886=TAS, GO:0031295=TAS, GO:0042102=TAS, GO:0016021=IEA, GO:0007166=IDA, GO:0009897=IEA, GO:0012505=IEA, GO:0042130=IEA} T cell costimulation, cell surface receptor signaling pathway, immune response, negative regulation of T cell proliferation, positive regulation of T cell proliferation, positive regulation of interleukin-10 secretion, signal transduction endomembrane system, external side of plasma membrane, integral to membrane, plasma membrane protein binding Human UniProtKB:Q15116 CD276 HGNC UniProtKB {GO:0005515=PMID:18650384, GO:0030501=GO_REF:0000019, GO:0008283=PMID:11224528, GO:0005102=PMID:11224528, GO:0042130=GO_REF:0000019, GO:0045085=GO_REF:0000019, GO:0045669=GO_REF:0000019, GO:0006955=PMID:11224528, GO:0042110=PMID:18650384, GO:0016020=GO_REF:0000038, GO:0045077=GO_REF:0000019, GO:0045078=PMID:11224528, GO:0050728=GO_REF:0000019, GO:0042102=PMID:11224528, GO:0050776=PMID:11224528, GO:0016021=PMID:15188059, GO:0009897=PMID:15188059} Q5ZPR3 CD276 antigen protein 20061106 {GO:0005515=IPI, GO:0030501=IEA, GO:0008283=NAS, GO:0005102=NAS, GO:0042130=IEA, GO:0045085=IEA, GO:0045669=IEA, GO:0006955=NAS, GO:0042110=IDA, GO:0016020=IEA, GO:0045077=IEA, GO:0045078=IDA, GO:0050728=IEA, GO:0042102=IDA, GO:0050776=NAS, GO:0016021=NAS, GO:0009897=NAS} T cell activation, cell proliferation, immune response, negative regulation of T cell proliferation, negative regulation of inflammatory response, negative regulation of interferon-gamma biosynthetic process, negative regulation of interleukin-2 biosynthetic process, positive regulation of T cell proliferation, positive regulation of bone mineralization, positive regulation of interferon-gamma biosynthetic process, positive regulation of osteoblast differentiation, regulation of immune response external side of plasma membrane, integral to membrane, membrane protein binding, receptor binding Human CD28 UniProtKB UniProtKB {GO:0005515=PMID:9784967, GO:0005886=Reactome:REACT_147854, GO:0002863=GO_REF:0000019, GO:0031295=Reactome:REACT_19344, GO:0042089=PMID:8717514, GO:0002020=PMID:12777399, GO:0042802=PMID:3159820, GO:0005829=Reactome:REACT_11164, GO:0006955=GO_REF:0000002, GO:0007173=Reactome:REACT_9417, GO:0006959=PMID:8717514, GO:0045944=GO_REF:0000019, GO:0042102=GO_REF:0000024, GO:0046641=GO_REF:0000019, GO:0016032=Reactome:REACT_6185, GO:0045070=PMID:7492435, GO:0048011=Reactome:REACT_11061, GO:0048015=Reactome:REACT_12464, GO:0045727=PMID:12028592, GO:0045840=GO_REF:0000024, GO:0015026=PMID:9784967, GO:0050690=Reactome:REACT_11149, GO:0045086=GO_REF:0000024, GO:0045066=PMID:18641304, GO:0016020=GO_REF:0000002, GO:0005887=PMID:9784967, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0005070=PMID:19641626, GO:0045060=GO_REF:0000019, GO:0048304=GO_REF:0000019, GO:0007166=PMID:9784967, GO:0009897=PMID:11390434} Q70WG0 CD28 antigen (Tp44), isoform CRA_b protein 20051214 {GO:0005515=IPI, GO:0005886=TAS, GO:0002863=IEA, GO:0031295=TAS, GO:0042089=TAS, GO:0002020=IPI, GO:0042802=NAS, GO:0005829=TAS, GO:0006955=IEA, GO:0007173=TAS, GO:0006959=TAS, GO:0045944=IEA, GO:0042102=ISS, GO:0046641=IEA, GO:0016032=TAS, GO:0045070=NAS, GO:0048011=TAS, GO:0048015=TAS, GO:0045727=NAS, GO:0045840=ISS, GO:0015026=TAS, GO:0050690=TAS, GO:0045086=ISS, GO:0045066=IDA, GO:0016020=IEA, GO:0005887=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0005070=IDA, GO:0045060=IEA, GO:0048304=IEA, GO:0007166=TAS, GO:0009897=IDA} T cell costimulation, cell surface receptor signaling pathway, cytokine biosynthetic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, humoral immune response, immune response, innate immune response, negative thymic T cell selection, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of T cell proliferation, positive regulation of alpha-beta T cell proliferation, positive regulation of inflammatory response to antigenic stimulus, positive regulation of interleukin-2 biosynthetic process, positive regulation of isotype switching to IgG isotypes, positive regulation of mitosis, positive regulation of transcription from RNA polymerase II promoter, positive regulation of translation, positive regulation of viral genome replication, regulation of defense response to virus by virus, regulatory T cell differentiation, viral reproduction cytosol, external side of plasma membrane, integral to plasma membrane, membrane, plasma membrane SH3/SH2 adaptor activity, coreceptor activity, identical protein binding, protease binding, protein binding Human UniProtKB:P10747 CD2AP HPA UniProtKB {GO:0005515=PMID:21988832, GO:0017124=PMID:10339567, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0015629=PMID:10339567, GO:0001726=PMID:10339567, GO:0006930=PMID:10339567, GO:0007165=PMID:10339567, GO:0007067=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0031941=PMID:10339567, GO:0006461=PMID:10339567, GO:0005200=PMID:10339567, GO:0051301=GO_REF:0000037} Q9Y5K6 CD2-associated protein protein 20080205 {GO:0005515=IPI, GO:0017124=IPI, GO:0005886=IDA, GO:0005730=IDA, GO:0015629=TAS, GO:0001726=IDA, GO:0006930=TAS, GO:0007165=NAS, GO:0007067=IEA, GO:0005737=IDA, GO:0031941=IDA, GO:0006461=TAS, GO:0005200=TAS, GO:0051301=IEA} cell division, mitosis, protein complex assembly, signal transduction, substrate-dependent cell migration, cell extension actin cytoskeleton, cytoplasm, filamentous actin, nucleolus, plasma membrane, ruffle SH3 domain binding, protein binding, structural constituent of cytoskeleton Human CD2BP2 BHF-UCL UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0000244=PMID:15840814, GO:0005515=PMID:15840814, GO:0010467=Reactome:REACT_71, GO:0005634=PMID:15840814, GO:0005737=GO_REF:0000039, GO:0016607=PMID:15840814, GO:0000398=Reactome:REACT_467, GO:0010923=PMID:19389623, GO:0043021=PMID:15840814, GO:0005654=PMID:15840814, GO:0005682=PMID:15840814, GO:0046540=PMID:15840814} O95400 CD2 antigen cytoplasmic tail-binding protein 2 protein 20091118 {GO:0008380=TAS, GO:0000244=NAS, GO:0005515=IPI, GO:0010467=TAS, GO:0005634=IDA, GO:0005737=IEA, GO:0016607=IDA, GO:0000398=TAS, GO:0010923=IDA, GO:0043021=IDA, GO:0005654=IDA, GO:0005682=IDA, GO:0046540=IDA} RNA splicing, assembly of spliceosomal tri-snRNP, gene expression, mRNA splicing, via spliceosome, negative regulation of phosphatase activity U4/U6 x U5 tri-snRNP complex, U5 snRNP, cytoplasm, nuclear speck, nucleoplasm, nucleus protein binding, ribonucleoprotein complex binding Human UniProtKB:P83876 CD300A UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037} Q9UGN4 CMRF35-like molecule 8 protein 20130413 {GO:0005886=IEA, GO:0016021=IEA, GO:0007155=IEA} cell adhesion integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 CD300C PINC UniProtKB {GO:0006968=PMID:1349532, GO:0005887=PMID:1349532, GO:0004888=PMID:1349532} Q08708 CMRF35-like molecule 6 protein 20030904 {GO:0006968=TAS, GO:0005887=TAS, GO:0004888=TAS} cellular defense response integral to plasma membrane transmembrane signaling receptor activity Human CD300E Reactome UniProtKB {GO:0005886=Reactome:REACT_147704, GO:0045087=Reactome:REACT_6802, GO:0016021=GO_REF:0000037} Q496F6 CMRF35-like molecule 2 protein 20120221 {GO:0005886=TAS, GO:0045087=TAS, GO:0016021=IEA} innate immune response integral to membrane, plasma membrane Human CD300LB Reactome UniProtKB {GO:0005886=Reactome:REACT_147706, GO:0045087=Reactome:REACT_6802, GO:0016021=GO_REF:0000037} A8K4G0 CMRF35-like molecule 7 protein 20120806 {GO:0005886=TAS, GO:0045087=TAS, GO:0016021=IEA} innate immune response integral to membrane, plasma membrane Human CD300LF UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q8TDQ1 CMRF35-like molecule 1 protein 20130413 {GO:0005886=IEA, GO:0016021=IEA} integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 CD302 MGI UniProtKB {GO:0006909=PMID:17947679, GO:0005902=GO_REF:0000039, GO:0030246=GO_REF:0000002, GO:0030175=PMID:17947679, GO:0016021=GO_REF:0000037, GO:0005938=PMID:17947679} Q8IX05 CD302 antigen protein 20120402 {GO:0006909=IDA, GO:0005902=IEA, GO:0030246=IEA, GO:0030175=IDA, GO:0016021=IEA, GO:0005938=IDA} phagocytosis cell cortex, filopodium, integral to membrane, microvillus carbohydrate binding Human CD320 LIFEdb UniProtKB {GO:0003674=GO_REF:0000015, GO:0031419=PMID:18779389, GO:0005886=PMID:18779389, GO:0005783=GO_REF:0000054, GO:0016021=GO_REF:0000037, GO:0001558=PMID:10727470, GO:0008083=GO_REF:0000037} Q9NPF0 CD320 antigen protein 20100607 {GO:0003674=ND, GO:0031419=IDA, GO:0005886=IDA, GO:0005783=IDA, GO:0016021=IEA, GO:0001558=NAS, GO:0008083=IEA} regulation of cell growth endoplasmic reticulum, integral to membrane, plasma membrane cobalamin binding, growth factor activity, molecular_function Human CD33 MGI UniProtKB {GO:0007165=PMID:10611343, GO:0008285=PMID:10611343, GO:0005886=PMID:3139766, GO:0005887=PMID:3139766, GO:0007267=PMID:10611343, GO:0004872=PMID:10611343, GO:0007155=GO_REF:0000037, GO:0009897=PMID:20660734} P20138 Myeloid cell surface antigen CD33 protein 20110510 {GO:0007165=TAS, GO:0008285=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0007267=TAS, GO:0004872=TAS, GO:0007155=IEA, GO:0009897=IDA} cell adhesion, cell-cell signaling, negative regulation of cell proliferation, signal transduction external side of plasma membrane, integral to plasma membrane, plasma membrane receptor activity Human CD34 InterPro UniProtKB {GO:0071657=PMID:9815891, GO:0005886=Reactome:REACT_11230, GO:0042482=PMID:12939361, GO:0008283=GO_REF:0000024, GO:0050900=GO_REF:0000024, GO:0005764=GO_REF:0000024, GO:0016337=PMID:15249540, GO:0016324=GO_REF:0000024, GO:0009925=GO_REF:0000024, GO:0048870=PMID:17261663, GO:0072254=PMID:1868864, GO:1900041=PMID:9815891, GO:1900168=PMID:17505307, GO:0007155=GO_REF:0000002, GO:0030097=PMID:15969628, GO:0072089=PMID:17261663, GO:0043199=GO_REF:0000019, GO:0003158=PMID:17261663, GO:0038001=PMID:21835908, GO:0007165=PMID:17261663, GO:0071425=PMID:21873977, GO:0036053=GO_REF:0000024, GO:0016020=GO_REF:0000002, GO:0005887=PMID:9042286, GO:0003094=PMID:20354148, GO:0050776=Reactome:REACT_11152, GO:0010629=PMID:15969628, GO:0071971=PMID:21835908, GO:0030246=PMID:15249540, GO:0035759=GO_REF:0000024, GO:0009897=PMID:15249540, GO:0008134=PMID:21873977} Q5JTA5 Hematopoietic progenitor cell antigen CD34 protein 20130413 {GO:0071657=IDA, GO:0005886=TAS, GO:0042482=IDA, GO:0008283=ISS, GO:0050900=ISS, GO:0005764=ISS, GO:0016337=IDA, GO:0016324=ISS, GO:0009925=ISS, GO:0048870=IEP, GO:0072254=IEP, GO:1900041=IMP, GO:1900168=IDA, GO:0007155=IEA, GO:0030097=IMP, GO:0072089=IEP, GO:0043199=IEA, GO:0003158=IEP, GO:0038001=IDA, GO:0007165=IEP, GO:0071425=IMP, GO:0036053=ISS, GO:0016020=IEA, GO:0005887=TAS, GO:0003094=IEP, GO:0050776=TAS, GO:0010629=IMP, GO:0071971=IDA, GO:0030246=IDA, GO:0035759=ISS, GO:0009897=IC, GO:0008134=IPI} cell adhesion, cell motility, cell proliferation, cell-cell adhesion, endothelium development, extracellular vesicular exosome assembly, glomerular filtration, hematopoietic stem cell proliferation, hemopoiesis, leukocyte migration, mesangial cell-matrix adhesion, metanephric glomerular mesangial cell differentiation, negative regulation of gene expression, negative regulation of interleukin-2 secretion, paracrine signaling, positive regulation of glial cell line-derived neurotrophic factor secretion, positive regulation of granulocyte colony-stimulating factor production, positive regulation of odontogenesis, regulation of immune response, signal transduction, stem cell proliferation apical plasma membrane, basal plasma membrane, external side of plasma membrane, glomerular endothelium fenestra, integral to plasma membrane, lysosome, membrane, plasma membrane carbohydrate binding, sulfate binding, transcription factor binding Human InterPro:IPR008083 CD36 BHF-UCL UniProtKB {GO:0032755=GO_REF:0000019, GO:0002474=Reactome:REACT_75820, GO:0035634=GO_REF:0000019, GO:0019915=PMID:10772654, GO:0050830=GO_REF:0000019, GO:0050731=GO_REF:0000019, GO:0030301=PMID:12376530, GO:0042992=GO_REF:0000019, GO:0060100=GO_REF:0000019, GO:0005041=PMID:10772654, GO:0015911=PMID:17416590, GO:0042953=PMID:10772654, GO:0002755=Reactome:REACT_6788, GO:0043123=GO_REF:0000019, GO:0044130=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0038124=Reactome:REACT_8006, GO:0005794=GO_REF:0000019, GO:0009986=GO_REF:0000024, GO:0038123=Reactome:REACT_8005, GO:0032760=GO_REF:0000019, GO:0010744=PMID:10772654, GO:0034134=Reactome:REACT_7980, GO:0030169=PMID:10772654, GO:0030168=Reactome:REACT_798, GO:0043277=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0002224=Reactome:REACT_6966, GO:0055096=GO_REF:0000019, GO:0005887=PMID:9568716, GO:0045087=Reactome:REACT_6802, GO:0045121=GO_REF:0000019, GO:2000379=GO_REF:0000019, GO:0001954=PMID:17416590, GO:0009897=GO_REF:0000019, GO:0070053=GO_REF:0000024, GO:0008035=GO_REF:0000019, GO:0006629=PMID:7518447, GO:0034142=Reactome:REACT_6894, GO:0007263=PMID:17416590, GO:0005886=Reactome:REACT_150418, GO:0070892=GO_REF:0000019, GO:0071447=GO_REF:0000019, GO:0032735=GO_REF:0000019, GO:0019934=PMID:17416590, GO:0044281=Reactome:REACT_111217, GO:2000334=GO_REF:0000019, GO:2000121=GO_REF:0000019, GO:0008289=PMID:10772654, GO:0034383=PMID:10772654, GO:0034381=PMID:12376530, GO:0031092=Reactome:REACT_21394, GO:0007155=GO_REF:0000037, GO:0044539=PMID:22022213, GO:0050431=GO_REF:0000024, GO:0071813=PMID:9568716, GO:0042590=Reactome:REACT_111119, GO:0010886=GO_REF:0000019, GO:0006910=GO_REF:0000019, GO:0045335=Reactome:REACT_111116, GO:0051636=GO_REF:0000019, GO:0071221=GO_REF:0000019, GO:0071223=GO_REF:0000019, GO:0071222=GO_REF:0000019, GO:0016020=PMID:2468669, GO:0007596=Reactome:REACT_604, GO:0030194=GO_REF:0000019, GO:0002576=Reactome:REACT_318, GO:0051637=GO_REF:0000019, GO:0060907=GO_REF:0000019, GO:0002479=Reactome:REACT_111174, GO:0016021=GO_REF:0000038, GO:0043410=GO_REF:0000019, GO:0007166=GO_REF:0000019} P16671 Platelet glycoprotein 4 protein 20081021 {GO:0032755=IEA, GO:0002474=TAS, GO:0035634=IEA, GO:0019915=IMP, GO:0050830=IEA, GO:0050731=IEA, GO:0030301=ISS, GO:0042992=IEA, GO:0060100=IEA, GO:0005041=IMP, GO:0015911=IDA, GO:0042953=IMP, GO:0002755=TAS, GO:0043123=IEA, GO:0044130=IEA, GO:0044255=TAS, GO:0038124=TAS, GO:0005794=IEA, GO:0009986=ISS, GO:0038123=TAS, GO:0032760=IEA, GO:0010744=IMP, GO:0034134=TAS, GO:0030169=IDA, GO:0030168=TAS, GO:0043277=IEA, GO:0000122=IEA, GO:0002224=TAS, GO:0055096=IEA, GO:0005887=TAS, GO:0045087=TAS, GO:0045121=IEA, GO:2000379=IEA, GO:0001954=IDA, GO:0009897=IEA, GO:0070053=ISS, GO:0008035=IEA, GO:0006629=NAS, GO:0034142=TAS, GO:0007263=IDA, GO:0005886=TAS, GO:0070892=IEA, GO:0071447=IEA, GO:0032735=IEA, GO:0019934=IDA, GO:0044281=TAS, GO:2000334=IEA, GO:2000121=IEA, GO:0008289=IDA, GO:0034383=IMP, GO:0034381=ISS, GO:0031092=TAS, GO:0007155=IEA, GO:0044539=IDA, GO:0050431=ISS, GO:0071813=IDA, GO:0042590=TAS, GO:0010886=IEA, GO:0006910=IEA, GO:0045335=TAS, GO:0051636=IEA, GO:0071221=IEA, GO:0071223=IEA, GO:0071222=IEA, GO:0016020=TAS, GO:0007596=TAS, GO:0030194=IEA, GO:0002576=TAS, GO:0051637=IEA, GO:0060907=IEA, GO:0002479=TAS, GO:0016021=IEA, GO:0043410=IEA, GO:0007166=IEA} MyD88-dependent toll-like receptor signaling pathway, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic cell clearance, blood coagulation, cGMP-mediated signaling, cell adhesion, cell surface receptor signaling pathway, cellular lipid metabolic process, cellular response to bacterial lipopeptide, cellular response to hydroperoxide, cellular response to lipopolysaccharide, cellular response to lipoteichoic acid, cholesterol transport, defense response to Gram-positive bacterium, innate immune response, lipid metabolic process, lipid storage, lipoprotein transport, long-chain fatty acid import, low-density lipoprotein particle clearance, low-density lipoprotein particle mediated signaling, negative regulation of growth of symbiont in host, negative regulation of transcription factor import into nucleus, negative regulation of transcription from RNA polymerase II promoter, nitric oxide mediated signal transduction, phagocytosis, recognition, plasma lipoprotein particle clearance, plasma membrane long-chain fatty acid transport, platelet activation, platelet degranulation, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of MAPK cascade, positive regulation of blood coagulation, positive regulation of blood microparticle formation, positive regulation of cell-matrix adhesion, positive regulation of cholesterol storage, positive regulation of interleukin-12 production, positive regulation of interleukin-6 production, positive regulation of macrophage cytokine production, positive regulation of macrophage derived foam cell differentiation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of phagocytosis, engulfment, positive regulation of reactive oxygen species metabolic process, positive regulation of tumor necrosis factor production, regulation of removal of superoxide radicals, response to stilbenoid, small molecule metabolic process, toll-like receptor 2 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway Golgi apparatus, cell surface, external side of plasma membrane, integral to membrane, integral to plasma membrane, membrane, membrane raft, phagocytic vesicle, plasma membrane, platelet alpha granule membrane Gram-negative bacterial cell surface binding, Gram-positive bacterial cell surface binding, high-density lipoprotein particle binding, lipid binding, lipoprotein particle binding, lipoteichoic acid receptor activity, low-density lipoprotein particle binding, low-density lipoprotein receptor activity, thrombospondin receptor activity, transforming growth factor beta binding Human UniProtKB:Q07969 CD38 PINC UniProtKB {GO:0050853=PMID:17875758, GO:0005886=GO_REF:0000019, GO:0030307=GO_REF:0000019, GO:0030890=PMID:17875758, GO:0005634=GO_REF:0000019, GO:0060292=GO_REF:0000019, GO:0007204=GO_REF:0000019, GO:0045779=GO_REF:0000019, GO:0045907=GO_REF:0000019, GO:0032024=GO_REF:0000019, GO:0032526=GO_REF:0000019, GO:0032355=GO_REF:0000019, GO:0033194=GO_REF:0000019, GO:0070555=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:0043066=PMID:17875758, GO:0016849=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0042493=PMID:17875758, GO:0097190=PMID:10777496, GO:0007165=PMID:8253715, GO:0003953=GO_REF:0000003, GO:0016020=PMID:8253715, GO:0032570=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0045893=PMID:17875758, GO:0045892=PMID:17875758} P28907 ADP-ribosyl cyclase 1 protein 20030904 {GO:0050853=IMP, GO:0005886=IEA, GO:0030307=IEA, GO:0030890=IMP, GO:0005634=IEA, GO:0060292=IEA, GO:0007204=IEA, GO:0045779=IEA, GO:0045907=IEA, GO:0032024=IEA, GO:0032526=IEA, GO:0032355=IEA, GO:0033194=IEA, GO:0070555=IEA, GO:0001666=IEA, GO:0007565=IEA, GO:0043066=IMP, GO:0016849=IEA, GO:0009986=IEA, GO:0042493=IMP, GO:0097190=TAS, GO:0007165=NAS, GO:0003953=IEA, GO:0016020=TAS, GO:0032570=IEA, GO:0016021=IEA, GO:0045893=IMP, GO:0045892=IMP} B cell receptor signaling pathway, apoptotic signaling pathway, elevation of cytosolic calcium ion concentration, female pregnancy, long term synaptic depression, negative regulation of apoptotic process, negative regulation of bone resorption, negative regulation of transcription, DNA-dependent, positive regulation of B cell proliferation, positive regulation of cell growth, positive regulation of insulin secretion, positive regulation of transcription, DNA-dependent, positive regulation of vasoconstriction, response to drug, response to estradiol stimulus, response to hydroperoxide, response to hypoxia, response to interleukin-1, response to progesterone stimulus, response to retinoic acid, signal transduction cell surface, integral to membrane, membrane, nucleus, plasma membrane NAD+ nucleosidase activity, phosphorus-oxygen lyase activity Human CD3D Reactome UniProtKB {GO:0050852=Reactome:REACT_12526, GO:0046982=PMID:9485181, GO:0005886=Reactome:REACT_19146, GO:0031295=Reactome:REACT_19344, GO:0003713=PMID:2017177, GO:0045059=GO_REF:0000024, GO:0042105=GO_REF:0000019, GO:0005737=PMID:1831653, GO:0016020=GO_REF:0000002, GO:0030217=PMID:2017177, GO:0042101=PMID:8176201, GO:0045944=PMID:2017177, GO:0050776=Reactome:REACT_11152, GO:0016021=GO_REF:0000037, GO:0007166=PMID:9485181, GO:0004888=PMID:9485181} P04234 T-cell surface glycoprotein CD3 delta chain protein 20070516 {GO:0050852=TAS, GO:0046982=IPI, GO:0005886=TAS, GO:0031295=TAS, GO:0003713=IDA, GO:0045059=ISS, GO:0042105=IEA, GO:0005737=NAS, GO:0016020=IEA, GO:0030217=IDA, GO:0042101=IDA, GO:0045944=IDA, GO:0050776=TAS, GO:0016021=IEA, GO:0007166=IC, GO:0004888=IC} T cell costimulation, T cell differentiation, T cell receptor signaling pathway, cell surface receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, positive thymic T cell selection, regulation of immune response T cell receptor complex, alpha-beta T cell receptor complex, cytoplasm, integral to membrane, membrane, plasma membrane protein heterodimerization activity, transcription coactivator activity, transmembrane signaling receptor activity Human CD3E Reactome UniProtKB {GO:0050852=Reactome:REACT_12526, GO:0032753=GO_REF:0000019, GO:0017124=PMID:12110186, GO:0005886=Reactome:REACT_19146, GO:0031295=Reactome:REACT_19344, GO:0050731=GO_REF:0000019, GO:0030159=PMID:9886373, GO:0045879=GO_REF:0000019, GO:0050850=GO_REF:0000019, GO:0042105=GO_REF:0000019, GO:0042608=PMID:11186279, GO:0007172=PMID:8490660, GO:0042101=PMID:8176201, GO:0042102=PMID:12110186, GO:0046641=GO_REF:0000019, GO:0032729=GO_REF:0000019, GO:0001772=GO_REF:0000019, GO:0019901=PMID:12110186, GO:0046982=PMID:9485181, GO:0007584=GO_REF:0000019, GO:0042981=PMID:12567487, GO:0045086=GO_REF:0000019, GO:0042110=PMID:12110186, GO:0006461=PMID:9886373, GO:0007186=PMID:8530500, GO:0016020=GO_REF:0000002, GO:0005887=PMID:9485181, GO:0050776=Reactome:REACT_11152, GO:0002669=GO_REF:0000019, GO:0045060=GO_REF:0000019, GO:0005057=PMID:1370449, GO:0007169=PMID:8530500, GO:0009897=PMID:17213291, GO:0007166=PMID:12110186, GO:0004888=PMID:9485181} P07766 T-cell surface glycoprotein CD3 epsilon chain protein 20070515 {GO:0050852=TAS, GO:0032753=IEA, GO:0017124=IPI, GO:0005886=TAS, GO:0031295=TAS, GO:0050731=IEA, GO:0030159=NAS, GO:0045879=IEA, GO:0050850=IEA, GO:0042105=IEA, GO:0042608=NAS, GO:0007172=TAS, GO:0042101=IDA, GO:0042102=IMP, GO:0046641=IEA, GO:0032729=IEA, GO:0001772=IEA, GO:0019901=NAS, GO:0046982=IPI, GO:0007584=IEA, GO:0042981=NAS, GO:0045086=IEA, GO:0042110=NAS, GO:0006461=NAS, GO:0007186=TAS, GO:0016020=IEA, GO:0005887=NAS, GO:0050776=TAS, GO:0002669=IEA, GO:0045060=IEA, GO:0005057=TAS, GO:0007169=TAS, GO:0009897=IDA, GO:0007166=NAS, GO:0004888=NAS} G-protein coupled receptor signaling pathway, T cell activation, T cell costimulation, T cell receptor signaling pathway, cell surface receptor signaling pathway, negative regulation of smoothened signaling pathway, negative thymic T cell selection, positive regulation of T cell anergy, positive regulation of T cell proliferation, positive regulation of alpha-beta T cell proliferation, positive regulation of calcium-mediated signaling, positive regulation of interferon-gamma production, positive regulation of interleukin-2 biosynthetic process, positive regulation of interleukin-4 production, positive regulation of peptidyl-tyrosine phosphorylation, protein complex assembly, regulation of apoptotic process, regulation of immune response, response to nutrient, signal complex assembly, transmembrane receptor protein tyrosine kinase signaling pathway T cell receptor complex, alpha-beta T cell receptor complex, external side of plasma membrane, immunological synapse, integral to plasma membrane, membrane, plasma membrane SH3 domain binding, T cell receptor binding, protein heterodimerization activity, protein kinase binding, receptor signaling complex scaffold activity, receptor signaling protein activity, transmembrane signaling receptor activity Human CD3EAP HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0005694=GO_REF:0000039, GO:0005736=GO_REF:0000019, GO:0003899=GO_REF:0000037, GO:0009303=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0000120=PMID:9426281, GO:0005634=GO_REF:0000052, GO:0007169=PMID:10373416} O15446 DNA-directed RNA polymerase I subunit RPA34 protein 20111111 {GO:0005739=IDA, GO:0005737=IDA, GO:0005694=IEA, GO:0005736=IEA, GO:0003899=IEA, GO:0009303=IEA, GO:0005730=IDA, GO:0000120=TAS, GO:0005634=IDA, GO:0007169=TAS} rRNA transcription, transmembrane receptor protein tyrosine kinase signaling pathway DNA-directed RNA polymerase I complex, RNA polymerase I transcription factor complex, chromosome, cytoplasm, mitochondrion, nucleolus, nucleus DNA-directed RNA polymerase activity Human CD3G Reactome UniProtKB {GO:0050852=Reactome:REACT_12526, GO:0005886=Reactome:REACT_160317, GO:0046982=PMID:9485181, GO:0031295=Reactome:REACT_19344, GO:0030159=PMID:12794121, GO:0042981=PMID:12407027, GO:0015031=PMID:12794121, GO:0042105=GO_REF:0000019, GO:0042110=PMID:12407027, GO:0042608=PMID:11186279, GO:0006461=PMID:12794121, GO:0007163=PMID:12407027, GO:0016020=GO_REF:0000002, GO:0005887=PMID:9485181, GO:0045087=Reactome:REACT_6802, GO:0042101=PMID:9485181, GO:0050776=Reactome:REACT_11152, GO:0038096=Reactome:REACT_160123, GO:0007166=PMID:12407027, GO:0004888=PMID:12794121} P09693 T-cell surface glycoprotein CD3 gamma chain protein 20110908 {GO:0050852=TAS, GO:0005886=TAS, GO:0046982=IPI, GO:0031295=TAS, GO:0030159=NAS, GO:0042981=IMP, GO:0015031=IMP, GO:0042105=IEA, GO:0042110=NAS, GO:0042608=NAS, GO:0006461=NAS, GO:0007163=IMP, GO:0016020=IEA, GO:0005887=NAS, GO:0045087=TAS, GO:0042101=NAS, GO:0050776=TAS, GO:0038096=TAS, GO:0007166=IMP, GO:0004888=IMP} Fc-gamma receptor signaling pathway involved in phagocytosis, T cell activation, T cell costimulation, T cell receptor signaling pathway, cell surface receptor signaling pathway, establishment or maintenance of cell polarity, innate immune response, protein complex assembly, protein transport, regulation of apoptotic process, regulation of immune response T cell receptor complex, alpha-beta T cell receptor complex, integral to plasma membrane, membrane, plasma membrane T cell receptor binding, protein heterodimerization activity, receptor signaling complex scaffold activity, transmembrane signaling receptor activity Human CD4 Reactome UniProtKB {GO:0005515=PMID:19333378, GO:0050852=Reactome:REACT_12526, GO:0022415=Reactome:REACT_6266, GO:0042289=PMID:8512039, GO:0005886=Reactome:REACT_116084, GO:0030260=Reactome:REACT_6903, GO:0031295=Reactome:REACT_19344, GO:0050731=GO_REF:0000019, GO:0001816=GO_REF:0000019, GO:0042803=PMID:12444132, GO:0050850=GO_REF:0000019, GO:0006955=PMID:8512039, GO:0001948=PMID:10922058, GO:0042101=PMID:8512039, GO:0045860=PMID:2118992, GO:0016032=Reactome:REACT_6256, GO:0004872=PMID:10413516, GO:0032507=PMID:15128768, GO:0007155=GO_REF:0000002, GO:0050863=PMID:1533274, GO:0019901=PMID:7486703, GO:0015026=PMID:8512039, GO:0045234=PMID:15128768, GO:0050690=Reactome:REACT_11166, GO:0045058=PMID:9551897, GO:0006948=PMID:9166430, GO:0050829=GO_REF:0000019, GO:0045086=PMID:1901411, GO:0007165=PMID:9558100, GO:0042110=GO_REF:0000019, GO:0030217=PMID:1533274, GO:0045087=Reactome:REACT_6802, GO:0050870=GO_REF:0000019, GO:0005789=Reactome:REACT_9071, GO:0005788=GO_REF:0000019, GO:0008270=PMID:9668045, GO:0045121=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0019899=PMID:19333378, GO:0007169=PMID:8512039, GO:0005769=Reactome:REACT_11227, GO:0009897=PMID:17213291, GO:0007166=PMID:9780207, GO:0007167=PMID:10358157, GO:0004888=PMID:10358157, GO:0005201=PMID:12444132} P01730 T-cell surface glycoprotein CD4 protein 20070516 {GO:0005515=IPI, GO:0050852=TAS, GO:0022415=TAS, GO:0042289=NAS, GO:0005886=TAS, GO:0030260=TAS, GO:0031295=TAS, GO:0050731=IEA, GO:0001816=IEA, GO:0042803=IDA, GO:0050850=IEA, GO:0006955=NAS, GO:0001948=IPI, GO:0042101=NAS, GO:0045860=IDA, GO:0016032=TAS, GO:0004872=TAS, GO:0032507=IDA, GO:0007155=IEA, GO:0050863=IDA, GO:0019901=IPI, GO:0015026=NAS, GO:0045234=IDA, GO:0050690=TAS, GO:0045058=IDA, GO:0006948=IDA, GO:0050829=IEA, GO:0045086=NAS, GO:0007165=TAS, GO:0042110=IEA, GO:0030217=IDA, GO:0045087=TAS, GO:0050870=IEA, GO:0005789=TAS, GO:0005788=IEA, GO:0008270=IDA, GO:0045121=IEA, GO:0016021=IEA, GO:0019899=IPI, GO:0007169=NAS, GO:0005769=TAS, GO:0009897=IDA, GO:0007166=TAS, GO:0007167=TAS, GO:0004888=TAS, GO:0005201=NAS} T cell activation, T cell costimulation, T cell differentiation, T cell receptor signaling pathway, T cell selection, cell adhesion, cell surface receptor signaling pathway, cytokine production, defense response to Gram-negative bacterium, entry into host cell, enzyme linked receptor protein signaling pathway, immune response, induction by virus of host cell-cell fusion, innate immune response, maintenance of protein location in cell, positive regulation of T cell activation, positive regulation of calcium-mediated signaling, positive regulation of interleukin-2 biosynthetic process, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of protein kinase activity, protein palmitoleylation, regulation of T cell activation, regulation of defense response to virus by virus, signal transduction, transmembrane receptor protein tyrosine kinase signaling pathway, viral reproduction, viral reproductive process T cell receptor complex, early endosome, endoplasmic reticulum lumen, endoplasmic reticulum membrane, external side of plasma membrane, integral to membrane, membrane raft, plasma membrane MHC class II protein binding, coreceptor activity, enzyme binding, extracellular matrix structural constituent, glycoprotein binding, protein binding, protein homodimerization activity, protein kinase binding, receptor activity, transmembrane signaling receptor activity, zinc ion binding Human CD40 BHF-UCL UniProtKB {GO:0005515=PMID:20676093, GO:0035631=GO_REF:0000024, GO:0005886=GO_REF:0000024, GO:0030890=GO_REF:0000019, GO:0032735=GO_REF:0000019, GO:0032855=PMID:21410936, GO:0043231=GO_REF:0000019, GO:0051607=GO_REF:0000019, GO:0006954=PMID:2475341, GO:0051092=PMID:21410936, GO:0090037=PMID:21410936, GO:0043406=PMID:21410936, GO:0042100=PMID:8605945, GO:0045944=PMID:21410936, GO:0043089=PMID:21410936, GO:0004872=PMID:10092834, GO:0004871=PMID:9671306, GO:0043123=PMID:12761501, GO:0031625=PMID:11279055, GO:0006874=PMID:21410936, GO:0042511=PMID:21410936, GO:0030168=PMID:9468137, GO:0005576=GO_REF:0000039, GO:0051023=GO_REF:0000019, GO:0002768=GO_REF:0000019, GO:0006461=PMID:10748139, GO:0005887=PMID:10748139, GO:0050776=Reactome:REACT_11152, GO:0001934=PMID:21410936, GO:0071260=PMID:19593445, GO:0019899=PMID:12223522, GO:2000353=PMID:12885753, GO:0048304=GO_REF:0000019, GO:0009897=GO_REF:0000019} P25942 Tumor necrosis factor receptor superfamily member 5 protein 20110223 {GO:0005515=IPI, GO:0035631=ISS, GO:0005886=ISS, GO:0030890=IEA, GO:0032735=IEA, GO:0032855=IMP, GO:0043231=IEA, GO:0051607=IEA, GO:0006954=TAS, GO:0051092=IMP, GO:0090037=IMP, GO:0043406=IMP, GO:0042100=NAS, GO:0045944=IMP, GO:0043089=IMP, GO:0004872=TAS, GO:0004871=TAS, GO:0043123=IEP, GO:0031625=IPI, GO:0006874=IMP, GO:0042511=IMP, GO:0030168=NAS, GO:0005576=IEA, GO:0051023=IEA, GO:0002768=IEA, GO:0006461=TAS, GO:0005887=TAS, GO:0050776=TAS, GO:0001934=IMP, GO:0071260=IEP, GO:0019899=IPI, GO:2000353=IDA, GO:0048304=IEA, GO:0009897=IEA} B cell proliferation, cellular calcium ion homeostasis, cellular response to mechanical stimulus, defense response to virus, immune response-regulating cell surface receptor signaling pathway, inflammatory response, platelet activation, positive regulation of B cell proliferation, positive regulation of Cdc42 GTPase activity, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of MAP kinase activity, positive regulation of NF-kappaB transcription factor activity, positive regulation of Rac GTPase activity, positive regulation of endothelial cell apoptotic process, positive regulation of interleukin-12 production, positive regulation of isotype switching to IgG isotypes, positive regulation of protein kinase C signaling cascade, positive regulation of protein phosphorylation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of tyrosine phosphorylation of Stat1 protein, protein complex assembly, regulation of immune response, regulation of immunoglobulin secretion CD40 receptor complex, external side of plasma membrane, extracellular region, integral to plasma membrane, intracellular membrane-bounded organelle, plasma membrane enzyme binding, protein binding, receptor activity, signal transducer activity, ubiquitin protein ligase binding Human CD40LG BHF-UCL UniProtKB {GO:0005164=GO_REF:0000002, GO:0043066=PMID:12697681, GO:0005886=Reactome:REACT_11241, GO:0045190=GO_REF:0000024, GO:0030168=PMID:9468137, GO:0032735=PMID:9922218, GO:0005125=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0051023=GO_REF:0000019, GO:0006954=PMID:9468137, GO:0005887=PMID:7678552, GO:0042100=PMID:8605945, GO:0050776=Reactome:REACT_11152, GO:0030183=GO_REF:0000019, GO:0007159=PMID:9468137, GO:0016021=PMID:9468137, GO:2000353=PMID:12885753, GO:0009897=GO_REF:0000019, GO:0048305=GO_REF:0000019, GO:0005174=PMID:9468137} P29965 CD40 ligand protein 20110223 {GO:0005164=IEA, GO:0043066=IDA, GO:0005886=TAS, GO:0045190=ISS, GO:0030168=IDA, GO:0032735=IDA, GO:0005125=IEA, GO:0005615=IEA, GO:0051023=IEA, GO:0006954=IDA, GO:0005887=TAS, GO:0042100=IDA, GO:0050776=TAS, GO:0030183=IEA, GO:0007159=NAS, GO:0016021=NAS, GO:2000353=IDA, GO:0009897=IEA, GO:0048305=IEA, GO:0005174=IPI} B cell differentiation, B cell proliferation, immunoglobulin secretion, inflammatory response, isotype switching, leukocyte cell-cell adhesion, negative regulation of apoptotic process, platelet activation, positive regulation of endothelial cell apoptotic process, positive regulation of interleukin-12 production, regulation of immune response, regulation of immunoglobulin secretion external side of plasma membrane, extracellular space, integral to membrane, integral to plasma membrane, plasma membrane CD40 receptor binding, cytokine activity, tumor necrosis factor receptor binding Human CD44 InterPro UniProtKB {GO:0005515=PMID:11207560, GO:0001658=GO_REF:0000019, GO:0005886=Reactome:REACT_120971, GO:0051216=PMID:11944887, GO:0019221=Reactome:REACT_25229, GO:0005518=PMID:2471973, GO:0050731=PMID:17045821, GO:0044281=Reactome:REACT_111217, GO:0016323=GO_REF:0000019, GO:0033138=PMID:17045821, GO:0005737=GO_REF:0000052, GO:0016337=PMID:1922057, GO:0005540=GO_REF:0000002, GO:0034116=PMID:15100360, GO:0070374=PMID:17045821, GO:0043154=PMID:19047049, GO:0016055=GO_REF:0000019, GO:0007155=GO_REF:0000002, GO:1900625=PMID:20522558, GO:0030203=Reactome:REACT_121315, GO:0060333=Reactome:REACT_25078, GO:0043066=PMID:17045821, GO:0005794=GO_REF:0000052, GO:0009986=PMID:16809613, GO:0005975=Reactome:REACT_474, GO:0002246=GO_REF:0000019, GO:0044344=PMID:19577615, GO:0060442=GO_REF:0000019, GO:0010628=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0007160=PMID:1922057, GO:0005887=PMID:1991450, GO:0070487=PMID:15100360, GO:0043518=PMID:17045821, GO:0030212=Reactome:REACT_121083, GO:0004415=PMID:17170110, GO:0030214=Reactome:REACT_120996, GO:0009897=GO_REF:0000019, GO:0004888=PMID:17045821} Q86UZ1 CD44 antigen protein 20130413 {GO:0005515=IPI, GO:0001658=IEA, GO:0005886=TAS, GO:0051216=IEP, GO:0019221=TAS, GO:0005518=NAS, GO:0050731=IDA, GO:0044281=TAS, GO:0016323=IEA, GO:0033138=IDA, GO:0005737=IDA, GO:0016337=NAS, GO:0005540=IEA, GO:0034116=IMP, GO:0070374=IDA, GO:0043154=IMP, GO:0016055=IEA, GO:0007155=IEA, GO:1900625=IMP, GO:0030203=TAS, GO:0060333=TAS, GO:0043066=IDA, GO:0005794=IDA, GO:0009986=IDA, GO:0005975=TAS, GO:0002246=IEA, GO:0044344=IDA, GO:0060442=IEA, GO:0010628=IEA, GO:0016020=IEA, GO:0007160=NAS, GO:0005887=NAS, GO:0070487=IMP, GO:0043518=IDA, GO:0030212=TAS, GO:0004415=IDA, GO:0030214=TAS, GO:0009897=IEA, GO:0004888=IDA} Wnt receptor signaling pathway, branching involved in prostate gland morphogenesis, branching involved in ureteric bud morphogenesis, carbohydrate metabolic process, cartilage development, cell adhesion, cell-cell adhesion, cell-matrix adhesion, cellular response to fibroblast growth factor stimulus, cytokine-mediated signaling pathway, glycosaminoglycan metabolic process, hyaluronan catabolic process, hyaluronan metabolic process, interferon-gamma-mediated signaling pathway, monocyte aggregation, negative regulation of DNA damage response, signal transduction by p53 class mediator, negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of ERK1 and ERK2 cascade, positive regulation of gene expression, positive regulation of heterotypic cell-cell adhesion, positive regulation of monocyte aggregation, positive regulation of peptidyl-serine phosphorylation, positive regulation of peptidyl-tyrosine phosphorylation, small molecule metabolic process, wound healing involved in inflammatory response Golgi apparatus, basolateral plasma membrane, cell surface, cytoplasm, external side of plasma membrane, integral to plasma membrane, membrane, plasma membrane collagen binding, hyaluronic acid binding, hyalurononglucosaminidase activity, protein binding, transmembrane signaling receptor activity Human InterPro:IPR001231 CD46 Reactome UniProtKB {GO:0030449=Reactome:REACT_118707, GO:0005794=GO_REF:0000019, GO:0001848=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0005886=Reactome:REACT_118673, GO:0007338=GO_REF:0000037, GO:0045916=GO_REF:0000019, GO:0016323=GO_REF:0000019, GO:0002079=GO_REF:0000039, GO:0005887=PMID:1711570, GO:0045087=Reactome:REACT_6802, GO:0019048=GO_REF:0000037, GO:0006958=GO_REF:0000037, GO:0006508=GO_REF:0000019, GO:0004872=PMID:8402913} P15529 Membrane cofactor protein protein 20130213 {GO:0030449=TAS, GO:0005794=IEA, GO:0001848=IEA, GO:0009986=IEA, GO:0005886=TAS, GO:0007338=IEA, GO:0045916=IEA, GO:0016323=IEA, GO:0002079=IEA, GO:0005887=TAS, GO:0045087=TAS, GO:0019048=IEA, GO:0006958=IEA, GO:0006508=IEA, GO:0004872=TAS} complement activation, classical pathway, innate immune response, negative regulation of complement activation, proteolysis, regulation of complement activation, single fertilization, virus-host interaction Golgi apparatus, basolateral plasma membrane, cell surface, inner acrosomal membrane, integral to plasma membrane, plasma membrane complement binding, receptor activity Human CD47 BHF-UCL UniProtKB {GO:0005515=PMID:15383453, GO:0008284=PMID:15383453, GO:0022409=PMID:15383453, GO:0005886=Reactome:REACT_24015, GO:0050900=Reactome:REACT_12051, GO:0009617=GO_REF:0000019, GO:0050766=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0005887=GO_REF:0000019, GO:0007229=PMID:8294396, GO:0050870=PMID:15383453, GO:0050729=GO_REF:0000019, GO:0007155=GO_REF:0000037, GO:0008228=GO_REF:0000019, GO:0070053=PMID:15700281, GO:0070062=GO_REF:0000019} Q08722 Leukocyte surface antigen CD47 protein 20081021 {GO:0005515=IPI, GO:0008284=IDA, GO:0022409=IDA, GO:0005886=TAS, GO:0050900=TAS, GO:0009617=IEA, GO:0050766=IEA, GO:0007596=TAS, GO:0005887=IEA, GO:0007229=TAS, GO:0050870=IDA, GO:0050729=IEA, GO:0007155=IEA, GO:0008228=IEA, GO:0070053=IPI, GO:0070062=IEA} blood coagulation, cell adhesion, integrin-mediated signaling pathway, leukocyte migration, opsonization, positive regulation of T cell activation, positive regulation of cell proliferation, positive regulation of cell-cell adhesion, positive regulation of inflammatory response, positive regulation of phagocytosis, response to bacterium extracellular vesicular exosome, integral to plasma membrane, plasma membrane protein binding, thrombospondin receptor activity Human UniProtKB:P07996 CD48 InterPro UniProtKB {GO:0005515=PMID:18296487, GO:0045576=GO_REF:0000019, GO:0043499=GO_REF:0000019, GO:0005886=Reactome:REACT_12018, GO:0006952=PMID:2828034, GO:0050900=Reactome:REACT_12051, GO:0003823=GO_REF:0000019, GO:0007165=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0042110=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:1693656, GO:0004872=GO_REF:0000002, GO:0045121=PMID:11313396, GO:0016021=GO_REF:0000002, GO:0046658=GO_REF:0000019, GO:0009897=GO_REF:0000019} Q8MGR0 CD48 antigen protein 20130413 {GO:0005515=IPI, GO:0045576=IEA, GO:0043499=IEA, GO:0005886=TAS, GO:0006952=TAS, GO:0050900=TAS, GO:0003823=IEA, GO:0007165=IEA, GO:0043234=IEA, GO:0042110=IEA, GO:0007596=TAS, GO:0005887=TAS, GO:0004872=IEA, GO:0045121=IDA, GO:0016021=IEA, GO:0046658=IEA, GO:0009897=IEA} T cell activation, blood coagulation, defense response, leukocyte migration, mast cell activation, signal transduction anchored to plasma membrane, external side of plasma membrane, integral to membrane, integral to plasma membrane, membrane raft, plasma membrane, protein complex antigen binding, eukaryotic cell surface binding, protein binding, receptor activity Human InterPro:IPR015631 CD5 MGI UniProtKB {GO:0005515=PMID:1711157, GO:0008037=PMID:1711157, GO:0005886=PMID:11390434, GO:0016020=GO_REF:0000002, GO:0005887=PMID:1711157, GO:0008283=PMID:3093892, GO:0031295=GO_REF:0000019, GO:0004872=PMID:1711157, GO:0009897=GO_REF:0000019, GO:0004888=PMID:3093892, GO:0005044=GO_REF:0000002} P06127 T-cell surface glycoprotein CD5 protein 20101102 {GO:0005515=IPI, GO:0008037=NAS, GO:0005886=IDA, GO:0016020=IEA, GO:0005887=NAS, GO:0008283=NAS, GO:0031295=IEA, GO:0004872=NAS, GO:0009897=IEA, GO:0004888=NAS, GO:0005044=IEA} T cell costimulation, cell proliferation, cell recognition external side of plasma membrane, integral to plasma membrane, membrane, plasma membrane protein binding, receptor activity, scavenger receptor activity, transmembrane signaling receptor activity Human CD52 PINC UniProtKB {GO:0045730=PMID:8223854, GO:0016020=PMID:1711975, GO:0005887=PMID:1711975, GO:0031225=GO_REF:0000037, GO:0007204=PMID:8223854} P31358 CAMPATH-1 antigen protein 20030904 {GO:0045730=NAS, GO:0016020=TAS, GO:0005887=TAS, GO:0031225=IEA, GO:0007204=IDA} elevation of cytosolic calcium ion concentration, respiratory burst anchored to membrane, integral to plasma membrane, membrane Human CD53 PINC UniProtKB {GO:0001772=PMID:21930792, GO:0005515=PMID:21930792, GO:0007165=PMID:8404042, GO:0005886=PMID:8452817, GO:0009986=GO_REF:0000019, GO:0016021=GO_REF:0000037} P19397 Leukocyte surface antigen CD53 protein 20030904 {GO:0001772=IDA, GO:0005515=IPI, GO:0007165=NAS, GO:0005886=TAS, GO:0009986=IEA, GO:0016021=IEA} signal transduction cell surface, immunological synapse, integral to membrane, plasma membrane protein binding Human CD55 Reactome UniProtKB {GO:0004857=GO_REF:0000019, GO:0045730=PMID:8223854, GO:0030449=Reactome:REACT_118707, GO:0005886=Reactome:REACT_118782, GO:0043434=GO_REF:0000019, GO:0060137=GO_REF:0000019, GO:0005576=Reactome:REACT_25290, GO:0031225=GO_REF:0000037, GO:0007283=GO_REF:0000019, GO:0007204=PMID:8223854, GO:0045916=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0005887=PMID:2433596, GO:0045087=Reactome:REACT_6802, GO:0006958=GO_REF:0000037, GO:0045121=PMID:11313396} P08174 Complement decay-accelerating factor protein 20101029 {GO:0004857=IEA, GO:0045730=NAS, GO:0030449=TAS, GO:0005886=TAS, GO:0043434=IEA, GO:0060137=IEA, GO:0005576=TAS, GO:0031225=IEA, GO:0007283=IEA, GO:0007204=IDA, GO:0045916=IEA, GO:0016324=IEA, GO:0005887=TAS, GO:0045087=TAS, GO:0006958=IEA, GO:0045121=IDA} complement activation, classical pathway, elevation of cytosolic calcium ion concentration, innate immune response, maternal process involved in parturition, negative regulation of complement activation, regulation of complement activation, respiratory burst, response to peptide hormone stimulus, spermatogenesis anchored to membrane, apical plasma membrane, extracellular region, integral to plasma membrane, membrane raft, plasma membrane enzyme inhibitor activity Human CD58 Reactome UniProtKB {GO:0005515=PMID:7544493, GO:0016337=PMID:7544493, GO:0005886=Reactome:REACT_12031, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:7544493, GO:0031225=GO_REF:0000037, GO:0050900=Reactome:REACT_12051, GO:0007155=PMID:10380930} P19256 Lymphocyte function-associated antigen 3 protein 20070515 {GO:0005515=IPI, GO:0016337=NAS, GO:0005886=TAS, GO:0007596=TAS, GO:0005887=NAS, GO:0031225=IEA, GO:0050900=TAS, GO:0007155=NAS} blood coagulation, cell adhesion, cell-cell adhesion, leukocyte migration anchored to membrane, integral to plasma membrane, plasma membrane protein binding Human CD59 IntAct UniProtKB {GO:0005515=PMID:20427317, GO:0043066=GO_REF:0000019, GO:0001848=GO_REF:0000019, GO:0005886=PMID:1381503, GO:0005615=GO_REF:0000019, GO:0031362=PMID:9724629, GO:0042383=GO_REF:0000019, GO:0016020=PMID:1381503, GO:0007596=PMID:1381503, GO:0001971=GO_REF:0000019, GO:0043218=GO_REF:0000019, GO:0042102=GO_REF:0000019, GO:0007166=PMID:7691713} P13987 CD59 glycoprotein protein 20130415 {GO:0005515=IPI, GO:0043066=IEA, GO:0001848=IEA, GO:0005886=NAS, GO:0005615=IEA, GO:0031362=IDA, GO:0042383=IEA, GO:0016020=TAS, GO:0007596=TAS, GO:0001971=IEA, GO:0043218=IEA, GO:0042102=IEA, GO:0007166=TAS} blood coagulation, cell surface receptor signaling pathway, negative regulation of activation of membrane attack complex, negative regulation of apoptotic process, positive regulation of T cell proliferation anchored to external side of plasma membrane, compact myelin, extracellular space, membrane, plasma membrane, sarcolemma complement binding, protein binding Human UniProtKB:O35587 CD5L PINC UniProtKB {GO:0006968=PMID:9045627, GO:0016020=GO_REF:0000002, GO:0006915=GO_REF:0000037, GO:0005576=PMID:14718574, GO:0005615=PMID:9045627, GO:0005044=GO_REF:0000002} O43866 CD5 antigen-like protein 20030904 {GO:0006968=TAS, GO:0016020=IEA, GO:0006915=IEA, GO:0005576=NAS, GO:0005615=TAS, GO:0005044=IEA} apoptotic process, cellular defense response extracellular region, extracellular space, membrane scavenger receptor activity Human CD6 PINC UniProtKB {GO:0009986=PMID:12493773, GO:0016020=GO_REF:0000002, GO:0005887=PMID:1919444, GO:0007155=GO_REF:0000037, GO:0005044=GO_REF:0000002} P30203 T-cell differentiation antigen CD6 protein 20030904 {GO:0009986=IDA, GO:0016020=IEA, GO:0005887=TAS, GO:0007155=IEA, GO:0005044=IEA} cell adhesion cell surface, integral to plasma membrane, membrane scavenger receptor activity Human CD63 Reactome UniProtKB {GO:0031088=Reactome:REACT_21266, GO:0009986=PMID:15647390, GO:0005886=Reactome:REACT_21266, GO:0005770=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0005765=GO_REF:0000039, GO:0005764=GO_REF:0000019, GO:2000680=PMID:15647390, GO:0005887=PMID:1993697, GO:0007596=Reactome:REACT_604, GO:0031902=GO_REF:0000039, GO:0002576=Reactome:REACT_318, GO:0016021=GO_REF:0000038, GO:0034613=PMID:15647390, GO:0010008=PMID:15229288} P08962 CD63 antigen protein 20041004 {GO:0031088=TAS, GO:0009986=IDA, GO:0005886=TAS, GO:0005770=IEA, GO:0030168=TAS, GO:0005765=IEA, GO:0005764=IEA, GO:2000680=IDA, GO:0005887=TAS, GO:0007596=TAS, GO:0031902=IEA, GO:0002576=TAS, GO:0016021=IEA, GO:0034613=IDA, GO:0010008=IDA} blood coagulation, cellular protein localization, platelet activation, platelet degranulation, regulation of rubidium ion transport cell surface, endosome membrane, integral to membrane, integral to plasma membrane, late endosome, late endosome membrane, lysosomal membrane, lysosome, plasma membrane, platelet dense granule membrane Human CD68 PINC UniProtKB {GO:0005886=GO_REF:0000039, GO:0016020=PMID:7680921, GO:0071310=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0005765=GO_REF:0000039, GO:0010008=GO_REF:0000039} P34810 Macrosialin protein 20030904 {GO:0005886=IEA, GO:0016020=TAS, GO:0071310=IEA, GO:0016021=IEA, GO:0005765=IEA, GO:0010008=IEA} cellular response to organic substance endosome membrane, integral to membrane, lysosomal membrane, membrane, plasma membrane Human CD69 PINC UniProtKB {GO:0005887=PMID:8340758, GO:0030246=GO_REF:0000002, GO:0035690=GO_REF:0000019, GO:0009897=GO_REF:0000019, GO:0004888=PMID:8340758} Q07108 Early activation antigen CD69 protein 20030904 {GO:0005887=TAS, GO:0030246=IEA, GO:0035690=IEA, GO:0009897=IEA, GO:0004888=TAS} cellular response to drug external side of plasma membrane, integral to plasma membrane carbohydrate binding, transmembrane signaling receptor activity Human CD7 PINC UniProtKB {GO:0006955=PMID:11485208, GO:0042110=PMID:11485208, GO:0048873=GO_REF:0000019, GO:0005886=PMID:3258561, GO:0016020=PMID:3501369, GO:0004872=PMID:11485208, GO:0016021=PMID:11485208, GO:0007169=PMID:11485208} P09564 T-cell antigen CD7 protein 20030904 {GO:0006955=TAS, GO:0042110=TAS, GO:0048873=IEA, GO:0005886=TAS, GO:0016020=TAS, GO:0004872=TAS, GO:0016021=TAS, GO:0007169=NAS} T cell activation, homeostasis of number of cells within a tissue, immune response, transmembrane receptor protein tyrosine kinase signaling pathway integral to membrane, membrane, plasma membrane receptor activity Human CD70 BHF-UCL UniProtKB {GO:0005515=PMID:12324477, GO:0005164=GO_REF:0000002, GO:0005886=PMID:11920585, GO:0008283=PMID:8120384, GO:0005102=PMID:8120384, GO:0007267=PMID:8387892, GO:0006917=PMID:9177220, GO:0002020=PMID:12777399, GO:0005125=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0007165=PMID:8387892, GO:0006955=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0005887=PMID:8120384} P32970 CD70 antigen protein 20110220 {GO:0005515=IPI, GO:0005164=IEA, GO:0005886=IDA, GO:0008283=TAS, GO:0005102=TAS, GO:0007267=TAS, GO:0006917=IDA, GO:0002020=IPI, GO:0005125=IEA, GO:0005615=IEA, GO:0007165=TAS, GO:0006955=IEA, GO:0016020=IEA, GO:0005887=TAS} cell proliferation, cell-cell signaling, immune response, induction of apoptosis, signal transduction extracellular space, integral to plasma membrane, membrane, plasma membrane cytokine activity, protease binding, protein binding, receptor binding, tumor necrosis factor receptor binding Human UniProtKB:P78325 CD72 Reactome UniProtKB {GO:0005515=PMID:1711157, GO:0005886=Reactome:REACT_19336, GO:0007411=Reactome:REACT_18266, GO:0005887=PMID:1711157, GO:0005102=PMID:1711157, GO:0030246=GO_REF:0000002, GO:0007155=PMID:1711157, GO:0004888=PMID:1711157} P21854 B-cell differentiation antigen CD72 protein 20070516 {GO:0005515=IPI, GO:0005886=TAS, GO:0007411=TAS, GO:0005887=IDA, GO:0005102=TAS, GO:0030246=IEA, GO:0007155=TAS, GO:0004888=NAS} axon guidance, cell adhesion integral to plasma membrane, plasma membrane carbohydrate binding, protein binding, receptor binding, transmembrane signaling receptor activity Human CD74 BHF-UCL UniProtKB {GO:0016064=GO_REF:0000024, GO:0043030=PMID:12782713, GO:0050731=PMID:17045821, GO:0005765=Reactome:REACT_121306, GO:0006886=GO_REF:0000024, GO:0042802=PMID:12782713, GO:0005622=PMID:12782713, GO:0001516=PMID:12782713, GO:0002906=GO_REF:0000019, GO:0070374=PMID:17045821, GO:0004896=PMID:17045821, GO:0009986=PMID:17045821, GO:0006952=GO_REF:0000019, GO:0019955=PMID:17567581, GO:0090023=GO_REF:0000024, GO:0051085=GO_REF:0000019, GO:0002830=GO_REF:0000019, GO:0035718=PMID:17045821, GO:0009897=GO_REF:0000019, GO:0050998=GO_REF:0000019, GO:0042289=GO_REF:0000024, GO:0005886=Reactome:REACT_121063, GO:0008283=PMID:12782713, GO:0030890=PMID:12782713, GO:0048146=PMID:12782713, GO:0000187=GO_REF:0000019, GO:0019886=Reactome:REACT_121399, GO:0006955=GO_REF:0000002, GO:0001540=PMID:19849849, GO:0019883=PMID:10981873, GO:0019882=GO_REF:0000002, GO:0001961=PMID:12782713, GO:0045581=GO_REF:0000019, GO:0071556=Reactome:REACT_121334, GO:0045582=GO_REF:0000019, GO:0030658=Reactome:REACT_121063, GO:0043202=Reactome:REACT_121161, GO:0005773=PMID:19849849, GO:0012507=Reactome:REACT_121121, GO:0043066=PMID:17045821, GO:0005771=GO_REF:0000019, GO:0002792=PMID:19849849, GO:0035693=GO_REF:0000019, GO:0042613=GO_REF:0000024, GO:0002606=GO_REF:0000019, GO:0032588=Reactome:REACT_121309, GO:0045059=GO_REF:0000019, GO:0035691=GO_REF:0000019, GO:0045058=PMID:10981873, GO:2000343=GO_REF:0000024, GO:0035692=PMID:17045821, GO:0030666=Reactome:REACT_121177, GO:0007165=PMID:12782713, GO:0006461=GO_REF:0000024, GO:0016020=GO_REF:0000002, GO:0000139=Reactome:REACT_121309, GO:0060907=GO_REF:0000024, GO:0043518=PMID:17045821, GO:0045060=GO_REF:0000019, GO:0016021=PMID:12782713, GO:0030669=Reactome:REACT_121177} P04233 HLA class II histocompatibility antigen gamma chain protein 20110228 {GO:0016064=ISS, GO:0043030=NAS, GO:0050731=IDA, GO:0005765=TAS, GO:0006886=ISS, GO:0042802=TAS, GO:0005622=TAS, GO:0001516=IDA, GO:0002906=IEA, GO:0070374=IDA, GO:0004896=IDA, GO:0009986=IDA, GO:0006952=IEA, GO:0019955=IPI, GO:0090023=ISS, GO:0051085=IEA, GO:0002830=IEA, GO:0035718=IPI, GO:0009897=IEA, GO:0050998=IEA, GO:0042289=ISS, GO:0005886=TAS, GO:0008283=IDA, GO:0030890=IMP, GO:0048146=IMP, GO:0000187=IEA, GO:0019886=TAS, GO:0006955=IEA, GO:0001540=IPI, GO:0019883=NAS, GO:0019882=IEA, GO:0001961=IMP, GO:0045581=IEA, GO:0071556=TAS, GO:0045582=IEA, GO:0030658=TAS, GO:0043202=TAS, GO:0005773=IDA, GO:0012507=TAS, GO:0043066=IMP, GO:0005771=IEA, GO:0002792=IDA, GO:0035693=IEA, GO:0042613=ISS, GO:0002606=IEA, GO:0032588=TAS, GO:0045059=IEA, GO:0035691=IEA, GO:0045058=NAS, GO:2000343=ISS, GO:0035692=IDA, GO:0030666=TAS, GO:0007165=IDA, GO:0006461=ISS, GO:0016020=IEA, GO:0000139=TAS, GO:0060907=ISS, GO:0043518=IDA, GO:0045060=IEA, GO:0016021=IDA, GO:0030669=TAS} T cell selection, activation of MAPK activity, antigen processing and presentation, antigen processing and presentation of endogenous antigen, antigen processing and presentation of exogenous peptide antigen via MHC class II, cell proliferation, chaperone mediated protein folding requiring cofactor, defense response, immune response, immunoglobulin mediated immune response, intracellular protein transport, macrophage migration inhibitory factor signaling pathway, negative regulation of DNA damage response, signal transduction by p53 class mediator, negative regulation of T cell differentiation, negative regulation of apoptotic process, negative regulation of mature B cell apoptotic process, negative regulation of peptide secretion, negative thymic T cell selection, positive regulation of B cell proliferation, positive regulation of ERK1 and ERK2 cascade, positive regulation of T cell differentiation, positive regulation of chemokine (C-X-C motif) ligand 2 production, positive regulation of cytokine-mediated signaling pathway, positive regulation of dendritic cell antigen processing and presentation, positive regulation of fibroblast proliferation, positive regulation of macrophage cytokine production, positive regulation of neutrophil chemotaxis, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of type 2 immune response, positive thymic T cell selection, prostaglandin biosynthetic process, protein complex assembly, regulation of macrophage activation, signal transduction ER to Golgi transport vesicle membrane, Golgi membrane, MHC class II protein complex, NOS2-CD74 complex, cell surface, clathrin-coated endocytic vesicle membrane, endocytic vesicle membrane, external side of plasma membrane, integral to lumenal side of endoplasmic reticulum membrane, integral to membrane, intracellular, lysosomal lumen, lysosomal membrane, macrophage migration inhibitory factor receptor complex, membrane, multivesicular body, plasma membrane, trans-Golgi network membrane, transport vesicle membrane, vacuole MHC class II protein binding, beta-amyloid binding, cytokine binding, cytokine receptor activity, identical protein binding, macrophage migration inhibitory factor binding, nitric-oxide synthase binding Human UniProtKB:P04441 CD79A Reactome UniProtKB {GO:0050853=GO_REF:0000024, GO:0042113=GO_REF:0000024, GO:0019815=GO_REF:0000024, GO:0005886=Reactome:REACT_118834, GO:0042100=GO_REF:0000024, GO:0005771=GO_REF:0000024, GO:0030183=GO_REF:0000024, GO:0045121=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0009897=GO_REF:0000024, GO:0004888=GO_REF:0000002} P11912 B-cell antigen receptor complex-associated protein alpha chain protein 20101102 {GO:0050853=ISS, GO:0042113=ISS, GO:0019815=ISS, GO:0005886=TAS, GO:0042100=ISS, GO:0005771=ISS, GO:0030183=ISS, GO:0045121=ISS, GO:0016021=IEA, GO:0009897=ISS, GO:0004888=IEA} B cell activation, B cell differentiation, B cell proliferation, B cell receptor signaling pathway B cell receptor complex, external side of plasma membrane, integral to membrane, membrane raft, multivesicular body, plasma membrane transmembrane signaling receptor activity Human CD79B HPA UniProtKB {GO:0050853=GO_REF:0000019, GO:0007165=PMID:8486355, GO:0019815=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0006955=PMID:8486355, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005887=PMID:8486355, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0009897=GO_REF:0000019, GO:0004888=GO_REF:0000002} P40259 B-cell antigen receptor complex-associated protein beta chain protein 20080205 {GO:0050853=IEA, GO:0007165=TAS, GO:0019815=IEA, GO:0005737=IDA, GO:0006955=TAS, GO:0005794=IDA, GO:0005886=IDA, GO:0005887=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0009897=IEA, GO:0004888=IEA} B cell receptor signaling pathway, immune response, signal transduction B cell receptor complex, Golgi apparatus, cytoplasm, external side of plasma membrane, integral to plasma membrane, nucleolus, nucleus, plasma membrane transmembrane signaling receptor activity Human CD80 UniProtKB UniProtKB {GO:0005515=PMID:21982860, GO:0048011=Reactome:REACT_11061, GO:0045425=PMID:9915850, GO:0005886=Reactome:REACT_147854, GO:0048015=Reactome:REACT_12464, GO:0031295=Reactome:REACT_19344, GO:0007267=PMID:9915850, GO:0050731=PMID:9915850, GO:0009967=PMID:9915850, GO:0015026=PMID:9915850, GO:0035556=PMID:9915850, GO:0045086=PMID:9915850, GO:0042110=PMID:9915850, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0019048=GO_REF:0000037, GO:0045627=PMID:9915850, GO:0046641=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0045893=PMID:9915850, GO:0009897=GO_REF:0000019} Q5DTB0 Costimulatory factor CD80 type 1 protein 20130413 {GO:0005515=IPI, GO:0048011=TAS, GO:0045425=NAS, GO:0005886=TAS, GO:0048015=TAS, GO:0031295=TAS, GO:0007267=IC, GO:0050731=IDA, GO:0009967=NAS, GO:0015026=NAS, GO:0035556=NAS, GO:0045086=NAS, GO:0042110=IC, GO:0007173=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0019048=IEA, GO:0045627=NAS, GO:0046641=IEA, GO:0016021=IEA, GO:0045893=NAS, GO:0009897=IEA} T cell activation, T cell costimulation, cell-cell signaling, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of T-helper 1 cell differentiation, positive regulation of alpha-beta T cell proliferation, positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, positive regulation of interleukin-2 biosynthetic process, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of signal transduction, positive regulation of transcription, DNA-dependent, virus-host interaction external side of plasma membrane, integral to membrane, plasma membrane coreceptor activity, protein binding Human UniProtKB-KW:KW-0812 CD81 Reactome UniProtKB {GO:0005515=PMID:11504738, GO:0001772=PMID:21930792, GO:0008284=PMID:14676841, GO:0005886=Reactome:REACT_11121, GO:0006661=PMID:14676841, GO:0008283=PMID:1695320, GO:0046488=PMID:14676841, GO:0050731=PMID:14676841, GO:0046718=PMID:14676841, GO:0000187=PMID:14676841, GO:0008104=PMID:14676841, GO:0005887=PMID:14676841, GO:0050776=Reactome:REACT_11152, GO:0016021=GO_REF:0000038, GO:0043128=PMID:14676841, GO:0046813=PMID:14676841} P60033 CD81 antigen protein 20070515 {GO:0005515=IPI, GO:0001772=IDA, GO:0008284=IDA, GO:0005886=TAS, GO:0006661=IDA, GO:0008283=TAS, GO:0046488=IDA, GO:0050731=IDA, GO:0046718=TAS, GO:0000187=IDA, GO:0008104=IDA, GO:0005887=IDA, GO:0050776=TAS, GO:0016021=IEA, GO:0043128=IDA, GO:0046813=TAS} activation of MAPK activity, cell proliferation, phosphatidylinositol biosynthetic process, phosphatidylinositol metabolic process, positive regulation of 1-phosphatidylinositol 4-kinase activity, positive regulation of cell proliferation, positive regulation of peptidyl-tyrosine phosphorylation, protein localization, regulation of immune response, viral entry into host cell, virion attachment, binding of host cell surface receptor immunological synapse, integral to membrane, integral to plasma membrane, plasma membrane protein binding Human CD82 IntAct UniProtKB {GO:0005515=PMID:15205336, GO:0005886=PMID:7754374, GO:0005887=PMID:1842498, GO:0016021=GO_REF:0000038} P27701 CD82 antigen protein 20130415 {GO:0005515=IPI, GO:0005886=TAS, GO:0005887=TAS, GO:0016021=IEA} integral to membrane, integral to plasma membrane, plasma membrane protein binding Human UniProtKB:Q8TAA9 CD83 PINC UniProtKB {GO:0007165=PMID:9310491, GO:0014070=GO_REF:0000019, GO:0005886=PMID:9310491, GO:0032733=GO_REF:0000019, GO:0005887=PMID:8422464, GO:0032743=GO_REF:0000019, GO:0006959=PMID:8422464, GO:0043372=GO_REF:0000019, GO:0032713=GO_REF:0000019, GO:0006952=PMID:1378080, GO:0009897=GO_REF:0000019} Q01151 CD83 antigen protein 20030904 {GO:0007165=TAS, GO:0014070=IEA, GO:0005886=TAS, GO:0032733=IEA, GO:0005887=TAS, GO:0032743=IEA, GO:0006959=TAS, GO:0043372=IEA, GO:0032713=IEA, GO:0006952=TAS, GO:0009897=IEA} defense response, humoral immune response, negative regulation of interleukin-4 production, positive regulation of CD4-positive, alpha-beta T cell differentiation, positive regulation of interleukin-10 production, positive regulation of interleukin-2 production, response to organic cyclic compound, signal transduction external side of plasma membrane, integral to plasma membrane, plasma membrane Human CD84 Reactome UniProtKB {GO:0005886=Reactome:REACT_12027, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:9310491, GO:0006952=PMID:9310491, GO:0004872=GO_REF:0000002, GO:0050900=Reactome:REACT_12051, GO:0007156=PMID:7797269} Q9UIB8 SLAM family member 5 protein 20071111 {GO:0005886=TAS, GO:0007596=TAS, GO:0005887=TAS, GO:0006952=TAS, GO:0004872=IEA, GO:0050900=TAS, GO:0007156=TAS} blood coagulation, defense response, homophilic cell adhesion, leukocyte migration integral to plasma membrane, plasma membrane receptor activity Human CD86 IntAct UniProtKB {GO:0005515=PMID:21982860, GO:0008284=PMID:7513726, GO:0005886=Reactome:REACT_147854, GO:0045404=PMID:9915850, GO:0031295=Reactome:REACT_19344, GO:0007267=PMID:9915850, GO:0043231=GO_REF:0000019, GO:0006955=PMID:7694363, GO:0051607=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0004872=PMID:7694363, GO:0045630=PMID:9915850, GO:0043017=PMID:9915850, GO:0048011=Reactome:REACT_11061, GO:0048015=Reactome:REACT_12464, GO:0015026=PMID:9915850, GO:0002224=GO_REF:0000019, GO:0045086=PMID:9915850, GO:0042113=GO_REF:0000019, GO:0042110=PMID:9915850, GO:0008543=Reactome:REACT_9470, GO:0019048=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0016021=PMID:9915850, GO:0045893=PMID:9915850, GO:0009897=GO_REF:0000019} P42081 T-lymphocyte activation antigen CD86 protein 20130415 {GO:0005515=IPI, GO:0008284=TAS, GO:0005886=TAS, GO:0045404=NAS, GO:0031295=TAS, GO:0007267=IC, GO:0043231=IEA, GO:0006955=TAS, GO:0051607=IEA, GO:0007173=TAS, GO:0004872=TAS, GO:0045630=NAS, GO:0043017=NAS, GO:0048011=TAS, GO:0048015=TAS, GO:0015026=NAS, GO:0002224=IEA, GO:0045086=NAS, GO:0042113=IEA, GO:0042110=IC, GO:0008543=TAS, GO:0019048=IEA, GO:0045087=TAS, GO:0016021=IC, GO:0045893=NAS, GO:0009897=IEA} B cell activation, T cell activation, T cell costimulation, cell-cell signaling, defense response to virus, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, immune response, innate immune response, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of T-helper 2 cell differentiation, positive regulation of cell proliferation, positive regulation of interleukin-2 biosynthetic process, positive regulation of interleukin-4 biosynthetic process, positive regulation of lymphotoxin A biosynthetic process, positive regulation of transcription, DNA-dependent, toll-like receptor signaling pathway, virus-host interaction external side of plasma membrane, integral to membrane, intracellular membrane-bounded organelle, plasma membrane coreceptor activity, protein binding, receptor activity Human UniProtKB:P16410 CD8A Reactome UniProtKB {GO:0005515=PMID:2470098, GO:0042288=PMID:11131152, GO:0005886=Reactome:REACT_11080, GO:0019901=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0015026=PMID:11131152, GO:0042803=GO_REF:0000019, GO:0050850=GO_REF:0000019, GO:0006955=PMID:11131152, GO:0045065=GO_REF:0000019, GO:0051607=GO_REF:0000019, GO:0042110=PMID:9830036, GO:0016020=GO_REF:0000038, GO:0005887=PMID:2496167, GO:0019882=PMID:2496167, GO:0042101=PMID:11131152, GO:0050776=Reactome:REACT_11152, GO:0016021=GO_REF:0000038, GO:0007169=PMID:9830036, GO:0009897=PMID:17213291, GO:0002456=GO_REF:0000019} P01732 T-cell surface glycoprotein CD8 alpha chain protein 20070514 {GO:0005515=IPI, GO:0042288=NAS, GO:0005886=TAS, GO:0019901=IEA, GO:0005576=IEA, GO:0015026=NAS, GO:0042803=IEA, GO:0050850=IEA, GO:0006955=NAS, GO:0045065=IEA, GO:0051607=IEA, GO:0042110=NAS, GO:0016020=IEA, GO:0005887=NAS, GO:0019882=NAS, GO:0042101=NAS, GO:0050776=TAS, GO:0016021=IEA, GO:0007169=NAS, GO:0009897=IDA, GO:0002456=IEA} T cell activation, T cell mediated immunity, antigen processing and presentation, cytotoxic T cell differentiation, defense response to virus, immune response, positive regulation of calcium-mediated signaling, regulation of immune response, transmembrane receptor protein tyrosine kinase signaling pathway T cell receptor complex, external side of plasma membrane, extracellular region, integral to membrane, integral to plasma membrane, membrane, plasma membrane MHC class I protein binding, coreceptor activity, protein binding, protein homodimerization activity, protein kinase binding Human CD8B Reactome UniProtKB {GO:0005515=PMID:2493728, GO:0042288=PMID:11131152, GO:0005886=Reactome:REACT_11125, GO:0005576=GO_REF:0000039, GO:0015026=PMID:11131152, GO:0050690=Reactome:REACT_11200, GO:0006955=PMID:11131152, GO:0042110=PMID:9830036, GO:0005887=PMID:3145195, GO:0042101=PMID:11131152, GO:0031901=Reactome:REACT_11144, GO:0050776=Reactome:REACT_11152, GO:0016032=Reactome:REACT_6185, GO:0007169=PMID:9830036, GO:0009897=GO_REF:0000019} P10966 T-cell surface glycoprotein CD8 beta chain protein 20130111 {GO:0005515=IPI, GO:0042288=NAS, GO:0005886=TAS, GO:0005576=IEA, GO:0015026=NAS, GO:0050690=TAS, GO:0006955=NAS, GO:0042110=NAS, GO:0005887=TAS, GO:0042101=NAS, GO:0031901=TAS, GO:0050776=TAS, GO:0016032=TAS, GO:0007169=NAS, GO:0009897=IEA} T cell activation, immune response, regulation of defense response to virus by virus, regulation of immune response, transmembrane receptor protein tyrosine kinase signaling pathway, viral reproduction T cell receptor complex, early endosome membrane, external side of plasma membrane, extracellular region, integral to plasma membrane, plasma membrane MHC class I protein binding, coreceptor activity, protein binding Human CD9 Reactome UniProtKB {GO:0005515=PMID:11504738, GO:0008285=GO_REF:0000019, GO:0005886=Reactome:REACT_21394, GO:0030913=GO_REF:0000024, GO:0030168=Reactome:REACT_798, GO:0006928=PMID:8478605, GO:0016324=GO_REF:0000019, GO:0005178=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:2037603, GO:0007342=PMID:14575715, GO:0007420=GO_REF:0000019, GO:0014003=GO_REF:0000019, GO:0002576=Reactome:REACT_318, GO:0009414=GO_REF:0000019, GO:0031092=Reactome:REACT_21394, GO:0016021=GO_REF:0000038, GO:0007155=PMID:7511626, GO:0009897=GO_REF:0000019} P21926 CD9 antigen protein 20100720 {GO:0005515=IPI, GO:0008285=IEA, GO:0005886=TAS, GO:0030913=ISS, GO:0030168=TAS, GO:0006928=IDA, GO:0016324=IEA, GO:0005178=IEA, GO:0007596=TAS, GO:0005887=NAS, GO:0007342=IDA, GO:0007420=IEA, GO:0014003=IEA, GO:0002576=TAS, GO:0009414=IEA, GO:0031092=TAS, GO:0016021=IEA, GO:0007155=IDA, GO:0009897=IEA} blood coagulation, brain development, cell adhesion, cellular component movement, fusion of sperm to egg plasma membrane, negative regulation of cell proliferation, oligodendrocyte development, paranodal junction assembly, platelet activation, platelet degranulation, response to water deprivation apical plasma membrane, external side of plasma membrane, integral to membrane, integral to plasma membrane, plasma membrane, platelet alpha granule membrane integrin binding, protein binding Human CD93 LIFEdb UniProtKB {GO:0006909=PMID:9047234, GO:0005515=PMID:15459234, GO:0009986=GO_REF:0000019, GO:0005886=GO_REF:0000054, GO:0005509=GO_REF:0000002, GO:0001849=PMID:11781389, GO:0016337=PMID:11994479, GO:0042116=PMID:9047234, GO:0019048=GO_REF:0000037, GO:0030246=GO_REF:0000002, GO:0016023=GO_REF:0000019, GO:0004872=PMID:9047234, GO:0016021=PMID:9047234} Q9NPY3 Complement component C1q receptor protein 20100607 {GO:0006909=NAS, GO:0005515=IPI, GO:0009986=IEA, GO:0005886=IDA, GO:0005509=IEA, GO:0001849=IDA, GO:0016337=IDA, GO:0042116=NAS, GO:0019048=IEA, GO:0030246=IEA, GO:0016023=IEA, GO:0004872=NAS, GO:0016021=IC} cell-cell adhesion, macrophage activation, phagocytosis, virus-host interaction cell surface, cytoplasmic membrane-bounded vesicle, integral to membrane, plasma membrane calcium ion binding, carbohydrate binding, complement component C1q binding, protein binding, receptor activity Human CD96 Reactome UniProtKB {GO:0006955=PMID:1313846, GO:0005886=Reactome:REACT_11207, GO:0005887=PMID:1313846, GO:0050776=Reactome:REACT_11152, GO:0007155=GO_REF:0000037} P40200 T-cell surface protein tactile protein 20130204 {GO:0006955=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0050776=TAS, GO:0007155=IEA} cell adhesion, immune response, regulation of immune response integral to plasma membrane, plasma membrane Human CD97 Reactome UniProtKB {GO:0005886=Reactome:REACT_25290, GO:0004930=GO_REF:0000037, GO:0005509=GO_REF:0000002, GO:0007267=PMID:7636245, GO:0006928=PMID:7636245, GO:0005615=GO_REF:0000039, GO:0006955=PMID:7636245, GO:0006954=PMID:8955192, GO:0016020=GO_REF:0000002, GO:0007186=PMID:8955192, GO:0007218=GO_REF:0000002, GO:0005887=PMID:8955192, GO:0007155=GO_REF:0000037, GO:0007166=PMID:7636245, GO:0004888=PMID:7636245} P48960 CD97 antigen protein 20091026 {GO:0005886=TAS, GO:0004930=IEA, GO:0005509=IEA, GO:0007267=TAS, GO:0006928=TAS, GO:0005615=IEA, GO:0006955=TAS, GO:0006954=TAS, GO:0016020=IEA, GO:0007186=TAS, GO:0007218=IEA, GO:0005887=TAS, GO:0007155=IEA, GO:0007166=TAS, GO:0004888=TAS} G-protein coupled receptor signaling pathway, cell adhesion, cell surface receptor signaling pathway, cell-cell signaling, cellular component movement, immune response, inflammatory response, neuropeptide signaling pathway extracellular space, integral to plasma membrane, membrane, plasma membrane G-protein coupled receptor activity, calcium ion binding, transmembrane signaling receptor activity Human CD99 PINC UniProtKB {GO:0005737=PMID:2479542, GO:0005886=PMID:2465491, GO:0005887=PMID:2479542, GO:0007155=GO_REF:0000037} P14209 CD99 antigen protein 20030904 {GO:0005737=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0007155=IEA} cell adhesion cytoplasm, integral to plasma membrane, plasma membrane Human CD99L2 UniProtKB UniProtKB {GO:0030054=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037} Q8TCZ2 CD99 antigen-like protein 2 protein 20130413 {GO:0030054=IEA, GO:0005886=IEA, GO:0016021=IEA, GO:0007155=IEA} cell adhesion cell junction, integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0038 CDA Reactome UniProtKB {GO:0030308=PMID:9596658, GO:0009972=PMID:9596658, GO:0045980=PMID:9596658, GO:0019858=PMID:7923172, GO:0055086=Reactome:REACT_1698, GO:0005576=PMID:9596658, GO:0044281=Reactome:REACT_111217, GO:0043097=Reactome:REACT_655, GO:0008655=PMID:9596658, GO:0042803=PMID:15689149, GO:0005829=Reactome:REACT_376, GO:0051289=PMID:9596658, GO:0001882=PMID:15689149, GO:0004126=Reactome:REACT_376, GO:0008270=PMID:9596658, GO:0006206=Reactome:REACT_957, GO:0007166=PMID:9596658} P32320 Cytidine deaminase protein 20130213 {GO:0030308=IDA, GO:0009972=IDA, GO:0045980=IDA, GO:0019858=TAS, GO:0055086=TAS, GO:0005576=TAS, GO:0044281=TAS, GO:0043097=TAS, GO:0008655=NAS, GO:0042803=IDA, GO:0005829=TAS, GO:0051289=IDA, GO:0001882=IDA, GO:0004126=EXP, GO:0008270=TAS, GO:0006206=TAS, GO:0007166=NAS} cell surface receptor signaling pathway, cytidine deamination, cytosine metabolic process, negative regulation of cell growth, negative regulation of nucleotide metabolic process, nucleobase-containing small molecule metabolic process, protein homotetramerization, pyrimidine nucleobase metabolic process, pyrimidine nucleoside salvage, pyrimidine-containing compound salvage, small molecule metabolic process cytosol, extracellular region cytidine deaminase activity, nucleoside binding, protein homodimerization activity, zinc ion binding Human CDAN1 UniProtKB UniProtKB {GO:0005515=PMID:22407294, GO:0005737=PMID:22407294, GO:0031497=PMID:22407294, GO:0005634=PMID:22407294, GO:0008156=PMID:22407294, GO:0016021=GO_REF:0000037} Q8IWY9 Codanin-1 protein 20121123 {GO:0005515=IPI, GO:0005737=IDA, GO:0031497=IMP, GO:0005634=IDA, GO:0008156=IMP, GO:0016021=IEA} chromatin assembly, negative regulation of DNA replication cytoplasm, integral to membrane, nucleus protein binding Human CDC123 HGNC UniProtKB {GO:0007346=PMID:15319434, GO:0008284=PMID:8601400, GO:0005737=PMID:10942595, GO:0007050=PMID:8601400, GO:0000080=GO_REF:0000019, GO:0051301=GO_REF:0000037} O75794 Cell division cycle protein 123 homolog protein 20071023 {GO:0007346=ISS, GO:0008284=TAS, GO:0005737=IDA, GO:0007050=TAS, GO:0000080=IEA, GO:0051301=IEA} G1 phase of mitotic cell cycle, cell cycle arrest, cell division, positive regulation of cell proliferation, regulation of mitotic cell cycle cytoplasm Human UniProtKB:Q05791 CDC14A HPA UniProtKB {GO:0005515=PMID:16221885, GO:0005813=PMID:21399614, GO:0007049=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0008283=PMID:9367992, GO:0005819=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0004721=PMID:9367992, GO:0005634=GO_REF:0000052, GO:0008138=GO_REF:0000002, GO:0004725=GO_REF:0000003, GO:0051301=GO_REF:0000037} Q9UNH5 Dual specificity protein phosphatase CDC14A protein 20101115 {GO:0005515=IPI, GO:0005813=IDA, GO:0007049=IEA, GO:0005737=IDA, GO:0008283=TAS, GO:0005819=IEA, GO:0005730=IDA, GO:0004721=TAS, GO:0005634=IDA, GO:0008138=IEA, GO:0004725=IEA, GO:0051301=IEA} cell cycle, cell division, cell proliferation centrosome, cytoplasm, nucleolus, nucleus, spindle phosphoprotein phosphatase activity, protein binding, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human CDC14B GOC UniProtKB {GO:0051488=PMID:18662541, GO:0031965=GO_REF:0000052, GO:0006470=PMID:18662541, GO:0006281=GO_REF:0000037, GO:0031572=PMID:18662541, GO:0005730=PMID:18662541, GO:0005654=PMID:18662541, GO:0005634=PMID:9367992, GO:0004722=PMID:18662541, GO:0008138=GO_REF:0000002, GO:0035335=PMID:9367992, GO:0004725=PMID:9367992} O60729 Dual specificity protein phosphatase CDC14B protein 20130413 {GO:0051488=IMP, GO:0031965=IDA, GO:0006470=IMP, GO:0006281=IEA, GO:0031572=IDA, GO:0005730=IDA, GO:0005654=IDA, GO:0005634=IDA, GO:0004722=IDA, GO:0008138=IEA, GO:0035335=IDA, GO:0004725=IDA} DNA repair, G2 DNA damage checkpoint, activation of anaphase-promoting complex activity, peptidyl-tyrosine dephosphorylation, protein dephosphorylation nuclear membrane, nucleolus, nucleoplasm, nucleus protein serine/threonine phosphatase activity, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human CDC16 ENSEMBL UniProtKB {GO:0005515=PMID:21988832, GO:0007094=Reactome:REACT_2137, GO:0005813=PMID:7736578, GO:0007088=PMID:7736578, GO:0008283=PMID:7736578, GO:0051437=Reactome:REACT_6904, GO:0005819=PMID:7736578, GO:0005634=GO_REF:0000019, GO:0051436=Reactome:REACT_6785, GO:0031145=Reactome:REACT_6871, GO:0051439=Reactome:REACT_6867, GO:0005829=Reactome:REACT_9035, GO:0005737=GO_REF:0000054, GO:0007067=PMID:7736578, GO:0070979=PMID:18485873, GO:0005680=PMID:21926987, GO:0000087=Reactome:REACT_910, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9051, GO:0005876=PMID:7736578, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000038} Q7Z651 Cell division cycle protein 16 homolog protein 20130413 {GO:0005515=IPI, GO:0007094=TAS, GO:0005813=IDA, GO:0007088=TAS, GO:0008283=TAS, GO:0051437=TAS, GO:0005819=TAS, GO:0005634=IEA, GO:0051436=TAS, GO:0031145=TAS, GO:0051439=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0007067=TAS, GO:0070979=IDA, GO:0005680=IDA, GO:0000087=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0005876=IDA, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle checkpoint, cell division, cell proliferation, mitosis, mitotic anaphase, mitotic cell cycle, mitotic spindle assembly checkpoint, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K11-linked ubiquitination, regulation of mitosis, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle anaphase-promoting complex, centrosome, cytoplasm, cytosol, nucleoplasm, nucleus, spindle, spindle microtubule protein binding Human Ensembl:ENSMUSP00000047950 CDC20 IntAct UniProtKB {GO:0005515=PMID:22340593, GO:0000236=Reactome:REACT_682, GO:0007094=Reactome:REACT_2137, GO:0090129=GO_REF:0000024, GO:0048471=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0016567=GO_REF:0000041, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_1951, GO:0051488=PMID:11459826, GO:0031915=GO_REF:0000024, GO:0005680=PMID:11459825, GO:0000087=Reactome:REACT_910, GO:0005813=GO_REF:0000019, GO:0005819=PMID:7513050, GO:0051437=Reactome:REACT_6821, GO:0051436=Reactome:REACT_1041, GO:0008022=PMID:10700282, GO:0051439=Reactome:REACT_6867, GO:0040020=GO_REF:0000019, GO:0000922=GO_REF:0000039, GO:0007049=PMID:9682218, GO:0050773=GO_REF:0000019, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_6891, GO:0000278=Reactome:REACT_152, GO:0019899=PMID:17443180, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q12834 Cell division cycle protein 20 homolog protein 20130415 {GO:0005515=IPI, GO:0000236=TAS, GO:0007094=TAS, GO:0090129=ISS, GO:0048471=IEA, GO:0008284=IEA, GO:0016567=IEA, GO:0031145=TAS, GO:0005829=TAS, GO:0051488=IDA, GO:0031915=ISS, GO:0005680=IDA, GO:0000087=TAS, GO:0005813=IEA, GO:0005819=TAS, GO:0051437=TAS, GO:0051436=TAS, GO:0008022=IPI, GO:0051439=TAS, GO:0040020=IEA, GO:0000922=IEA, GO:0007049=TAS, GO:0050773=IEA, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0019899=IPI, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, activation of anaphase-promoting complex activity, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle, cell cycle checkpoint, cell division, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, mitotic spindle assembly checkpoint, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of cell proliferation, positive regulation of synapse maturation, positive regulation of synaptic plasticity, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein ubiquitination, regulation of dendrite development, regulation of meiosis, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle anaphase-promoting complex, centrosome, cytosol, nucleoplasm, perinuclear region of cytoplasm, spindle, spindle pole enzyme binding, protein C-terminus binding, protein binding Human UniProtKB:Q13257 CDC23 LIFEdb UniProtKB {GO:0007094=Reactome:REACT_2137, GO:0006511=PMID:9790767, GO:0004842=PMID:12629511, GO:0007096=PMID:9790767, GO:0051437=Reactome:REACT_6904, GO:0051436=Reactome:REACT_6785, GO:0031145=Reactome:REACT_6871, GO:0051439=Reactome:REACT_6867, GO:0005829=Reactome:REACT_9035, GO:0005622=GO_REF:0000054, GO:0007049=PMID:12188893, GO:0007067=PMID:14657031, GO:0070979=PMID:18485873, GO:0005680=PMID:21926987, GO:0000087=Reactome:REACT_910, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9051, GO:0030071=PMID:9790767, GO:0007080=PMID:14657031, GO:0000278=Reactome:REACT_152, GO:0000080=PMID:12629511, GO:0000090=Reactome:REACT_1275, GO:0007091=PMID:9790767, GO:0051301=GO_REF:0000037} Q9UJX2 Cell division cycle protein 23 homolog protein 20100607 {GO:0007094=TAS, GO:0006511=TAS, GO:0004842=TAS, GO:0007096=TAS, GO:0051437=TAS, GO:0051436=TAS, GO:0031145=TAS, GO:0051439=TAS, GO:0005829=TAS, GO:0005622=IDA, GO:0007049=TAS, GO:0007067=IDA, GO:0070979=IDA, GO:0005680=IDA, GO:0000087=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0030071=IDA, GO:0007080=IDA, GO:0000278=TAS, GO:0000080=IDA, GO:0000090=TAS, GO:0007091=TAS, GO:0051301=IEA} G1 phase of mitotic cell cycle, M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle, cell cycle checkpoint, cell division, metaphase/anaphase transition of mitotic cell cycle, mitosis, mitotic anaphase, mitotic cell cycle, mitotic metaphase plate congression, mitotic spindle assembly checkpoint, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K11-linked ubiquitination, regulation of exit from mitosis, regulation of mitotic metaphase/anaphase transition, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, ubiquitin-dependent protein catabolic process anaphase-promoting complex, cytosol, intracellular, nucleoplasm ubiquitin-protein ligase activity Human CDC25A IntAct UniProtKB {GO:0009314=PMID:21376736, GO:0005515=PMID:7644510, GO:0019901=PMID:21376736, GO:0008283=PMID:11139144, GO:0005634=GO_REF:0000019, GO:0000079=PMID:11139144, GO:0005829=Reactome:REACT_6257, GO:0006260=Reactome:REACT_6769, GO:0000084=Reactome:REACT_899, GO:0005622=GO_REF:0000002, GO:0007067=GO_REF:0000037, GO:0034644=PMID:19966869, GO:0000082=Reactome:REACT_1783, GO:0005737=GO_REF:0000019, GO:0000086=Reactome:REACT_2203, GO:0000087=GO_REF:0000002, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_111167, GO:0000278=Reactome:REACT_152, GO:0004725=GO_REF:0000003, GO:0051301=GO_REF:0000037} P30304 M-phase inducer phosphatase 1 protein 20130415 {GO:0009314=IDA, GO:0005515=IPI, GO:0019901=IPI, GO:0008283=TAS, GO:0005634=IEA, GO:0000079=TAS, GO:0005829=TAS, GO:0006260=TAS, GO:0000084=TAS, GO:0005622=IEA, GO:0007067=IEA, GO:0034644=IDA, GO:0000082=TAS, GO:0005737=IEA, GO:0000086=TAS, GO:0000087=IEA, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0004725=IEA, GO:0051301=IEA} DNA replication, G1/S transition of mitotic cell cycle, G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, S phase of mitotic cell cycle, cell cycle checkpoint, cell division, cell proliferation, cellular response to UV, mitosis, mitotic cell cycle, regulation of cyclin-dependent protein serine/threonine kinase activity, response to radiation cytoplasm, cytosol, intracellular, nucleoplasm, nucleus protein binding, protein kinase binding, protein tyrosine phosphatase activity Human UniProtKB:P31946 CDC25B GOC UniProtKB {GO:0008284=PMID:8276402, GO:0005813=PMID:15908796, GO:0019901=PMID:15908796, GO:0001556=GO_REF:0000019, GO:0035335=PMID:9188863, GO:0005829=Reactome:REACT_6257, GO:0005622=GO_REF:0000029, GO:0007067=GO_REF:0000037, GO:0045931=PMID:17332740, GO:0000922=PMID:15908796, GO:0007144=GO_REF:0000019, GO:0000086=Reactome:REACT_2203, GO:0000087=GO_REF:0000002, GO:0045860=GO_REF:0000019, GO:0005654=Reactome:REACT_6255, GO:0006468=PMID:17332740, GO:0000278=Reactome:REACT_152, GO:0004725=PMID:9188863, GO:0051301=GO_REF:0000037} P30305 M-phase inducer phosphatase 2 protein 20130413 {GO:0008284=TAS, GO:0005813=IDA, GO:0019901=IPI, GO:0001556=IEA, GO:0035335=TAS, GO:0005829=TAS, GO:0005622=NAS, GO:0007067=IEA, GO:0045931=IMP, GO:0000922=IDA, GO:0007144=IEA, GO:0000086=TAS, GO:0000087=IEA, GO:0045860=IEA, GO:0005654=TAS, GO:0006468=IDA, GO:0000278=TAS, GO:0004725=TAS, GO:0051301=IEA} G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, cell division, female meiosis I, mitosis, mitotic cell cycle, oocyte maturation, peptidyl-tyrosine dephosphorylation, positive regulation of cell proliferation, positive regulation of mitotic cell cycle, positive regulation of protein kinase activity, protein phosphorylation centrosome, cytosol, intracellular, nucleoplasm, spindle pole protein kinase binding, protein tyrosine phosphatase activity Human CDC25C GOC UniProtKB {GO:0005515=PMID:17349584, GO:0007088=PMID:1828290, GO:0019901=PMID:14968113, GO:0008283=PMID:11139144, GO:0050699=PMID:10037602, GO:0005634=PMID:14968113, GO:0000079=PMID:11139144, GO:0035335=PMID:11078813, GO:0005829=Reactome:REACT_6279, GO:0006260=Reactome:REACT_6769, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000019, GO:0007067=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0000086=Reactome:REACT_2203, GO:0000087=GO_REF:0000002, GO:0051726=Reactome:REACT_1006, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_6279, GO:0000278=Reactome:REACT_152, GO:0004725=PMID:11078813, GO:0051301=GO_REF:0000037} P30307 M-phase inducer phosphatase 3 protein 20130413 {GO:0005515=IPI, GO:0007088=TAS, GO:0019901=IPI, GO:0008283=TAS, GO:0050699=IPI, GO:0005634=IDA, GO:0000079=TAS, GO:0035335=NAS, GO:0005829=TAS, GO:0006260=TAS, GO:0005622=IEA, GO:0005737=IEA, GO:0007067=IEA, GO:0019048=IEA, GO:0000086=TAS, GO:0000087=IEA, GO:0051726=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0004725=NAS, GO:0051301=IEA} DNA replication, G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, cell cycle checkpoint, cell division, cell proliferation, mitosis, mitotic cell cycle, peptidyl-tyrosine dephosphorylation, regulation of cell cycle, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of mitosis, virus-host interaction cytoplasm, cytosol, intracellular, nucleoplasm, nucleus WW domain binding, protein binding, protein kinase binding, protein tyrosine phosphatase activity Human CDC26 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0007094=Reactome:REACT_2137, GO:0051437=Reactome:REACT_6904, GO:0051436=Reactome:REACT_6785, GO:0031145=Reactome:REACT_6871, GO:0051439=Reactome:REACT_6867, GO:0005829=Reactome:REACT_9035, GO:0070979=PMID:18485873, GO:0005680=PMID:10922056, GO:0000087=Reactome:REACT_910, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9051, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q8NHZ8 Anaphase-promoting complex subunit CDC26 protein 20130415 {GO:0005515=IPI, GO:0007094=TAS, GO:0051437=TAS, GO:0051436=TAS, GO:0031145=TAS, GO:0051439=TAS, GO:0005829=TAS, GO:0070979=IDA, GO:0005680=IDA, GO:0000087=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle checkpoint, cell division, mitotic anaphase, mitotic cell cycle, mitotic spindle assembly checkpoint, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K11-linked ubiquitination, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle anaphase-promoting complex, cytosol, nucleoplasm protein binding Human UniProtKB:Q13042 CDC27 HPA UniProtKB {GO:0005515=PMID:22014574, GO:0007094=Reactome:REACT_2137, GO:0005813=PMID:7736578, GO:0008283=PMID:7736578, GO:0019903=PMID:21241890, GO:0051437=Reactome:REACT_6904, GO:0005730=GO_REF:0000052, GO:0005819=PMID:7736578, GO:0005634=GO_REF:0000052, GO:0051436=Reactome:REACT_6785, GO:0031145=Reactome:REACT_6871, GO:0051439=Reactome:REACT_6867, GO:0005829=Reactome:REACT_9035, GO:0005737=GO_REF:0000054, GO:0070979=PMID:18485873, GO:0005680=PMID:21926987, GO:0000087=Reactome:REACT_910, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9051, GO:0005876=PMID:7736578, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0007091=PMID:7736578, GO:0051301=GO_REF:0000038} P30260 Cell division cycle protein 27 homolog protein 20101115 {GO:0005515=IPI, GO:0007094=TAS, GO:0005813=IDA, GO:0008283=TAS, GO:0019903=IPI, GO:0051437=TAS, GO:0005730=IDA, GO:0005819=TAS, GO:0005634=IDA, GO:0051436=TAS, GO:0031145=TAS, GO:0051439=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0070979=IDA, GO:0005680=IDA, GO:0000087=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0005876=IDA, GO:0000278=TAS, GO:0000090=TAS, GO:0007091=IMP, GO:0051301=IEA} M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle checkpoint, cell division, cell proliferation, metaphase/anaphase transition of mitotic cell cycle, mitotic anaphase, mitotic cell cycle, mitotic spindle assembly checkpoint, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K11-linked ubiquitination, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle anaphase-promoting complex, centrosome, cytoplasm, cytosol, nucleolus, nucleoplasm, nucleus, spindle, spindle microtubule protein binding, protein phosphatase binding NOT Human CDC34 HPA UniProtKB {GO:0005515=PMID:19945379, GO:0000209=PMID:20347421, GO:0004842=PMID:20347421, GO:0016567=PMID:10373550, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0000082=PMID:8248134, GO:0006270=PMID:8248134, GO:0043161=PMID:20347421, GO:0070936=PMID:20061386, GO:0006464=PMID:8248134, GO:0043951=PMID:10373550} P49427 Ubiquitin-conjugating enzyme E2 R1 protein 20101115 {GO:0005515=IPI, GO:0000209=IDA, GO:0004842=IDA, GO:0016567=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0005524=IEA, GO:0005737=IDA, GO:0000082=NAS, GO:0006270=NAS, GO:0043161=IDA, GO:0070936=IDA, GO:0006464=NAS, GO:0043951=IDA} DNA replication initiation, G1/S transition of mitotic cell cycle, cellular protein modification process, negative regulation of cAMP-mediated signaling, proteasomal ubiquitin-dependent protein catabolic process, protein K48-linked ubiquitination, protein polyubiquitination, protein ubiquitination cytoplasm, nucleolus, nucleus ATP binding, protein binding, ubiquitin-protein ligase activity Human CDC37 HPA UniProtKB {GO:0005515=PMID:22939624, GO:0019901=GO_REF:0000002, GO:0051087=GO_REF:0000019, GO:0051879=GO_REF:0000019, GO:0031435=GO_REF:0000019, GO:0032587=GO_REF:0000019, GO:0000079=PMID:8666233, GO:0006605=PMID:8666233, GO:0043422=GO_REF:0000019, GO:0005829=Reactome:REACT_116154, GO:0060334=PMID:16280321, GO:0043234=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0060338=PMID:16280321, GO:0031072=PMID:9660753, GO:0051082=PMID:8666233} Q16543 Hsp90 co-chaperone Cdc37 protein 20120912 {GO:0005515=IPI, GO:0019901=IEA, GO:0051087=IEA, GO:0051879=IEA, GO:0031435=IEA, GO:0032587=IEA, GO:0000079=TAS, GO:0006605=TAS, GO:0043422=IEA, GO:0005829=TAS, GO:0060334=IMP, GO:0043234=IEA, GO:0005737=IDA, GO:0060338=IMP, GO:0031072=IPI, GO:0051082=TAS} protein targeting, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of interferon-gamma-mediated signaling pathway, regulation of type I interferon-mediated signaling pathway cytoplasm, cytosol, protein complex, ruffle membrane Hsp90 protein binding, chaperone binding, heat shock protein binding, mitogen-activated protein kinase kinase kinase binding, protein binding, protein kinase B binding, protein kinase binding, unfolded protein binding Human CDC37L1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q7L3B6 Hsp90 co-chaperone Cdc37-like 1 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 CDC40 Reactome UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0006406=Reactome:REACT_1597, GO:0006366=Reactome:REACT_1366, GO:0000398=Reactome:REACT_467, GO:0031124=Reactome:REACT_1849, GO:0005654=Reactome:REACT_1935, GO:0005681=PMID:9524131, GO:0071013=PMID:11991638} O60508 Pre-mRNA-processing factor 17 protein 20130213 {GO:0008380=TAS, GO:0010467=TAS, GO:0006369=TAS, GO:0006406=TAS, GO:0006366=TAS, GO:0000398=TAS, GO:0031124=TAS, GO:0005654=TAS, GO:0005681=TAS, GO:0071013=IDA} RNA splicing, gene expression, mRNA 3'-end processing, mRNA export from nucleus, mRNA splicing, via spliceosome, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter catalytic step 2 spliceosome, nucleoplasm, spliceosomal complex Human CDC42 ENSEMBL UniProtKB {GO:0045859=GO_REF:0000019, GO:0005515=PMID:10051605, GO:0072686=PMID:15642749, GO:0043497=GO_REF:0000019, GO:0060047=GO_REF:0000019, GO:0031424=GO_REF:0000019, GO:0046330=GO_REF:0000019, GO:0035088=GO_REF:0000019, GO:0072384=GO_REF:0000019, GO:0042995=GO_REF:0000019, GO:0051683=GO_REF:0000019, GO:0042802=PMID:9748241, GO:0031069=GO_REF:0000019, GO:0042692=Reactome:REACT_21303, GO:0005622=GO_REF:0000002, GO:0051489=PMID:14978216, GO:0043525=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0043552=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0007030=GO_REF:0000019, GO:0043025=PMID:21048939, GO:0031274=PMID:11035016, GO:0046847=GO_REF:0000019, GO:0051017=GO_REF:0000019, GO:0060684=GO_REF:0000019, GO:0007088=GO_REF:0000019, GO:0019901=PMID:21048939, GO:0005815=GO_REF:0000039, GO:0045740=GO_REF:0000019, GO:0042059=Reactome:REACT_12484, GO:0030496=PMID:15642749, GO:0031435=GO_REF:0000019, GO:0090316=GO_REF:0000019, GO:0006184=PMID:11035016, GO:0030742=GO_REF:0000019, GO:0051149=Reactome:REACT_21402, GO:0048554=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0051835=GO_REF:0000019, GO:0038096=Reactome:REACT_160123, GO:0034332=GO_REF:0000019, GO:0043005=PMID:21048939, GO:0030036=PMID:11035016, GO:0003161=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0007264=GO_REF:0000002, GO:0007097=GO_REF:0000019, GO:0031295=Reactome:REACT_19344, GO:0003924=PMID:11035016, GO:0031996=PMID:12612085, GO:0002040=GO_REF:0000019, GO:0030175=PMID:11035016, GO:0051233=PMID:15642749, GO:0003334=GO_REF:0000019, GO:0005829=Reactome:REACT_160291, GO:0005737=PMID:11260256, GO:0033138=GO_REF:0000019, GO:0031647=GO_REF:0000019, GO:0034191=PMID:16443932, GO:0035264=GO_REF:0000019, GO:0031333=PMID:11584266, GO:0071338=GO_REF:0000019, GO:0060661=GO_REF:0000019, GO:0030225=PMID:11260256, GO:0030141=GO_REF:0000019, GO:0060070=GO_REF:0000019, GO:0090136=GO_REF:0000019, GO:0051056=Reactome:REACT_11051, GO:0090135=GO_REF:0000019, GO:0042176=GO_REF:0000019, GO:0051988=PMID:15642749, GO:0048664=GO_REF:0000019, GO:0045177=GO_REF:0000019, GO:0060789=GO_REF:0000019, GO:0005525=GO_REF:0000019, GO:0010628=GO_REF:0000019, GO:0007163=PMID:11260256, GO:0000139=GO_REF:0000019, GO:0016020=GO_REF:0000038, GO:0007596=Reactome:REACT_604, GO:0010629=GO_REF:0000019, GO:0034613=GO_REF:0000019} Q5JYX0 Cell division control protein 42 homolog protein 20130413 {GO:0045859=IEA, GO:0005515=IPI, GO:0072686=IDA, GO:0043497=IEA, GO:0060047=IEA, GO:0031424=IEA, GO:0046330=IEA, GO:0035088=IEA, GO:0072384=IEA, GO:0042995=IEA, GO:0051683=IEA, GO:0042802=IPI, GO:0031069=IEA, GO:0042692=TAS, GO:0005622=IEA, GO:0051489=IDA, GO:0043525=IEA, GO:0007173=TAS, GO:0043552=IEA, GO:0007411=TAS, GO:0007030=IEA, GO:0043025=IDA, GO:0031274=IDA, GO:0046847=IEA, GO:0051017=IEA, GO:0060684=IEA, GO:0007088=IEA, GO:0019901=IPI, GO:0005815=IEA, GO:0045740=IEA, GO:0042059=TAS, GO:0030496=IDA, GO:0031435=IEA, GO:0090316=IEA, GO:0006184=TAS, GO:0030742=IEA, GO:0051149=TAS, GO:0048554=IEA, GO:0045087=TAS, GO:0051835=IEA, GO:0038096=TAS, GO:0034332=IEA, GO:0043005=IDA, GO:0030036=IDA, GO:0003161=IEA, GO:0005886=IEA, GO:0007264=IEA, GO:0007097=IEA, GO:0031295=TAS, GO:0003924=TAS, GO:0031996=IPI, GO:0002040=IEA, GO:0030175=IDA, GO:0051233=IDA, GO:0003334=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0033138=IEA, GO:0031647=IEA, GO:0034191=IPI, GO:0035264=IEA, GO:0031333=IPI, GO:0071338=IEA, GO:0060661=IEA, GO:0030225=TAS, GO:0030141=IEA, GO:0060070=IEA, GO:0090136=IEA, GO:0051056=TAS, GO:0090135=IEA, GO:0042176=IEA, GO:0051988=IMP, GO:0048664=IEA, GO:0045177=IEA, GO:0060789=IEA, GO:0005525=IEA, GO:0010628=IEA, GO:0007163=TAS, GO:0000139=IEA, GO:0016020=IEA, GO:0007596=TAS, GO:0010629=IEA, GO:0034613=IEA} Fc-gamma receptor signaling pathway involved in phagocytosis, GTP catabolic process, Golgi organization, T cell costimulation, actin cytoskeleton organization, actin filament branching, actin filament bundle assembly, adherens junction organization, axon guidance, blood coagulation, canonical Wnt receptor signaling pathway, cardiac conduction system development, cellular protein localization, epidermal growth factor receptor signaling pathway, epithelial cell-cell adhesion, epithelial-mesenchymal cell signaling, establishment of Golgi localization, establishment or maintenance of apical/basal cell polarity, establishment or maintenance of cell polarity, filopodium assembly, hair follicle morphogenesis, hair follicle placode formation, heart contraction, innate immune response, keratinization, keratinocyte development, macrophage differentiation, multicellular organism growth, muscle cell differentiation, negative regulation of epidermal growth factor receptor signaling pathway, negative regulation of gene expression, negative regulation of protein complex assembly, neuron fate determination, nuclear migration, organelle transport along microtubule, positive regulation of DNA replication, positive regulation of JNK cascade, positive regulation of gene expression, positive regulation of hair follicle cell proliferation, positive regulation of intracellular protein transport, positive regulation of metalloenzyme activity, positive regulation of muscle cell differentiation, positive regulation of neuron apoptotic process, positive regulation of peptidyl-serine phosphorylation, positive regulation of phosphatidylinositol 3-kinase activity, positive regulation of pseudopodium assembly, positive regulation of synapse structural plasticity, regulation of attachment of spindle microtubules to kinetochore, regulation of filopodium assembly, regulation of mitosis, regulation of protein catabolic process, regulation of protein heterodimerization activity, regulation of protein kinase activity, regulation of protein stability, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction, sprouting angiogenesis, submandibular salivary gland formation Golgi membrane, apical part of cell, cell projection, cytoplasm, cytosol, filopodium, intracellular, membrane, microtubule organizing center, midbody, mitotic spindle, neuron projection, neuronal cell body, plasma membrane, secretory granule, spindle midzone GTP binding, GTP-dependent protein binding, GTPase activity, apolipoprotein A-I receptor binding, identical protein binding, mitogen-activated protein kinase kinase kinase binding, protein binding, protein kinase binding, thioesterase binding Human Ensembl:ENSRNOP00000030928 CDC42BPA IntAct UniProtKB {GO:0000287=PMID:9092543, GO:0042641=PMID:18854160, GO:0031532=PMID:9418861, GO:0007097=GO_REF:0000019, GO:0031032=PMID:18854160, GO:0000226=GO_REF:0000019, GO:0005524=PMID:9092543, GO:0046872=GO_REF:0000038, GO:0042802=PMID:11283256, GO:0035556=GO_REF:0000002, GO:0005083=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0016477=PMID:18854160, GO:0004674=PMID:21457715, GO:0005911=GO_REF:0000024, GO:0006468=PMID:9092543, GO:0031252=GO_REF:0000024} Q5VT25 Serine/threonine-protein kinase MRCK alpha protein 20130415 {GO:0000287=IDA, GO:0042641=IDA, GO:0031532=IDA, GO:0007097=IEA, GO:0031032=IMP, GO:0000226=IEA, GO:0005524=IDA, GO:0046872=IEA, GO:0042802=IPI, GO:0035556=IEA, GO:0005083=IEA, GO:0005737=IEA, GO:0005543=IEA, GO:0016477=IMP, GO:0004674=IDA, GO:0005911=ISS, GO:0006468=IDA, GO:0031252=ISS} actin cytoskeleton reorganization, actomyosin structure organization, cell migration, intracellular signal transduction, microtubule cytoskeleton organization, nuclear migration, protein phosphorylation actomyosin, cell leading edge, cell-cell junction, cytoplasm ATP binding, identical protein binding, magnesium ion binding, metal ion binding, phospholipid binding, protein serine/threonine kinase activity, small GTPase regulator activity Human UniProtKB:Q5VT25 CDC42BPB PINC UniProtKB {GO:0000287=GO_REF:0000024, GO:0042641=PMID:18854160, GO:0031532=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0031032=PMID:18854160, GO:0005524=GO_REF:0000024, GO:0046872=GO_REF:0000038, GO:0035556=GO_REF:0000002, GO:0007165=PMID:9418861, GO:0005083=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0004672=PMID:21949762, GO:0005543=GO_REF:0000002, GO:0007163=PMID:9418861, GO:0016477=PMID:18854160, GO:0005911=GO_REF:0000024, GO:0004674=GO_REF:0000024, GO:0007010=PMID:9418861, GO:0017048=GO_REF:0000019, GO:0006468=PMID:21949762, GO:0005856=PMID:9418861, GO:0031252=GO_REF:0000024} Q9Y5S2 Serine/threonine-protein kinase MRCK beta protein 20030904 {GO:0000287=ISS, GO:0042641=IDA, GO:0031532=ISS, GO:0005886=IEA, GO:0031032=IMP, GO:0005524=ISS, GO:0046872=IEA, GO:0035556=IEA, GO:0007165=TAS, GO:0005083=IEA, GO:0005737=IEA, GO:0004672=IDA, GO:0005543=IEA, GO:0007163=TAS, GO:0016477=IMP, GO:0005911=ISS, GO:0004674=ISS, GO:0007010=TAS, GO:0017048=IEA, GO:0006468=IDA, GO:0005856=TAS, GO:0031252=ISS} actin cytoskeleton reorganization, actomyosin structure organization, cell migration, cytoskeleton organization, establishment or maintenance of cell polarity, intracellular signal transduction, protein phosphorylation, signal transduction actomyosin, cell leading edge, cell-cell junction, cytoplasm, cytoskeleton, plasma membrane ATP binding, Rho GTPase binding, magnesium ion binding, metal ion binding, phospholipid binding, protein kinase activity, protein serine/threonine kinase activity, small GTPase regulator activity Human CDC42BPG HPA UniProtKB {GO:0005515=PMID:21903422, GO:0035556=GO_REF:0000002, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000039, GO:0005083=GO_REF:0000002, GO:0000287=PMID:15194684, GO:0005543=GO_REF:0000002, GO:0031532=GO_REF:0000024, GO:0004674=PMID:15194684, GO:0006468=PMID:15194684, GO:0031252=PMID:15194684, GO:0005524=PMID:15194684} Q6DT37 Serine/threonine-protein kinase MRCK gamma protein 20100326 {GO:0005515=IPI, GO:0035556=IEA, GO:0005813=IDA, GO:0005737=IEA, GO:0005083=IEA, GO:0000287=IDA, GO:0005543=IEA, GO:0031532=ISS, GO:0004674=IDA, GO:0006468=IDA, GO:0031252=IDA, GO:0005524=IDA} actin cytoskeleton reorganization, intracellular signal transduction, protein phosphorylation cell leading edge, centrosome, cytoplasm ATP binding, magnesium ion binding, phospholipid binding, protein binding, protein serine/threonine kinase activity, small GTPase regulator activity Human CDC42EP1 HPA UniProtKB {GO:0005515=PMID:21988832, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0008360=PMID:11035016, GO:0031274=PMID:11035016, GO:0007266=GO_REF:0000019, GO:0015629=GO_REF:0000052, GO:0012505=GO_REF:0000039} Q00587 Cdc42 effector protein 1 protein 20080205 {GO:0005515=IPI, GO:0005737=IDA, GO:0005794=IDA, GO:0005886=IDA, GO:0008360=IDA, GO:0031274=IDA, GO:0007266=IEA, GO:0015629=IDA, GO:0012505=IEA} Rho protein signal transduction, positive regulation of pseudopodium assembly, regulation of cell shape Golgi apparatus, actin cytoskeleton, cytoplasm, endomembrane system, plasma membrane protein binding Human CDC42EP2 GOC UniProtKB {GO:0005515=PMID:11584266, GO:0030036=PMID:10430899, GO:0005886=PMID:10430899, GO:0008360=PMID:11035016, GO:0005100=PMID:10430899, GO:0012505=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0031334=PMID:11584266, GO:0030838=PMID:11035016, GO:0016020=PMID:11035016, GO:0032321=PMID:10430899, GO:0001515=GO_REF:0000019, GO:0015630=GO_REF:0000052, GO:0031274=PMID:11035016, GO:0007015=PMID:11035016, GO:0017049=PMID:11035016} O14613 Cdc42 effector protein 2 protein 20130413 {GO:0005515=IPI, GO:0030036=IDA, GO:0005886=IDA, GO:0008360=IDA, GO:0005100=IMP, GO:0012505=IEA, GO:0005737=IDA, GO:0031334=TAS, GO:0030838=IDA, GO:0016020=IDA, GO:0032321=IMP, GO:0001515=IEA, GO:0015630=IDA, GO:0031274=IDA, GO:0007015=NAS, GO:0017049=IPI} actin cytoskeleton organization, actin filament organization, positive regulation of Rho GTPase activity, positive regulation of actin filament polymerization, positive regulation of protein complex assembly, positive regulation of pseudopodium assembly, regulation of cell shape cytoplasm, endomembrane system, membrane, microtubule cytoskeleton, plasma membrane GTP-Rho binding, Rho GTPase activator activity, opioid peptide activity, protein binding Human CDC42EP3 LIFEdb UniProtKB {GO:0007165=PMID:11035016, GO:0005737=GO_REF:0000037, GO:0005519=PMID:11035016, GO:0016020=GO_REF:0000037, GO:0008360=GO_REF:0000037, GO:0015629=GO_REF:0000054, GO:0012505=GO_REF:0000039} Q9UKI2 Cdc42 effector protein 3 protein 20100607 {GO:0007165=TAS, GO:0005737=IEA, GO:0005519=TAS, GO:0016020=IEA, GO:0008360=IEA, GO:0015629=IDA, GO:0012505=IEA} regulation of cell shape, signal transduction actin cytoskeleton, cytoplasm, endomembrane system, membrane cytoskeletal regulatory protein binding Human CDC42EP4 HPA UniProtKB {GO:0005737=GO_REF:0000019, GO:0016020=GO_REF:0000037, GO:0008360=PMID:11035016, GO:0015630=GO_REF:0000052, GO:0031274=PMID:11035016, GO:0017049=PMID:11035016, GO:0007266=GO_REF:0000019, GO:0015629=GO_REF:0000052, GO:0012505=GO_REF:0000039} Q9H3Q1 Cdc42 effector protein 4 protein 20100326 {GO:0005737=IEA, GO:0016020=IEA, GO:0008360=IDA, GO:0015630=IDA, GO:0031274=IDA, GO:0017049=NAS, GO:0007266=IEA, GO:0015629=IDA, GO:0012505=IEA} Rho protein signal transduction, positive regulation of pseudopodium assembly, regulation of cell shape actin cytoskeleton, cytoplasm, endomembrane system, membrane, microtubule cytoskeleton GTP-Rho binding Human CDC42EP5 UniProtKB UniProtKB {GO:0005737=PMID:11035016, GO:0016020=PMID:11035016, GO:0030838=PMID:11035016, GO:0005886=GO_REF:0000019, GO:0008360=PMID:11035016, GO:0007254=GO_REF:0000019, GO:0031274=PMID:11035016, GO:0017049=PMID:11035016, GO:0007266=GO_REF:0000019, GO:0005856=GO_REF:0000039, GO:0012505=GO_REF:0000039} Q6NZY7 Cdc42 effector protein 5 protein 20050923 {GO:0005737=IDA, GO:0016020=IDA, GO:0030838=IDA, GO:0005886=IEA, GO:0008360=IDA, GO:0007254=IEA, GO:0031274=IDA, GO:0017049=IPI, GO:0007266=IEA, GO:0005856=IEA, GO:0012505=IEA} JNK cascade, Rho protein signal transduction, positive regulation of actin filament polymerization, positive regulation of pseudopodium assembly, regulation of cell shape cytoplasm, cytoskeleton, endomembrane system, membrane, plasma membrane GTP-Rho binding Human CDC42SE1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0006909=GO_REF:0000037, GO:0007165=PMID:10816584, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000039, GO:0008360=GO_REF:0000037, GO:0005095=PMID:10816584, GO:0005856=GO_REF:0000039} Q9NRR8 CDC42 small effector protein 1 protein 20111111 {GO:0005739=IDA, GO:0006909=IEA, GO:0007165=TAS, GO:0005737=IDA, GO:0005886=IEA, GO:0008360=IEA, GO:0005095=TAS, GO:0005856=IEA} phagocytosis, regulation of cell shape, signal transduction cytoplasm, cytoskeleton, mitochondrion, plasma membrane GTPase inhibitor activity Human CDC42SE2 HPA UniProtKB {GO:0006909=GO_REF:0000037, GO:0005515=PMID:10816584, GO:0005886=GO_REF:0000052, GO:0008360=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0001891=GO_REF:0000039, GO:0042995=GO_REF:0000037, GO:0009966=PMID:10816584, GO:0043231=GO_REF:0000052, GO:0005737=GO_REF:0000037, GO:0005198=PMID:10816584, GO:0005856=GO_REF:0000039} Q9NRR3 CDC42 small effector protein 2 protein 20110516 {GO:0006909=IEA, GO:0005515=IPI, GO:0005886=IDA, GO:0008360=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0001891=IEA, GO:0042995=IEA, GO:0009966=IDA, GO:0043231=IDA, GO:0005737=IEA, GO:0005198=IDA, GO:0005856=IEA} phagocytosis, regulation of cell shape, regulation of signal transduction cell projection, cytoplasm, cytoskeleton, intracellular membrane-bounded organelle, nucleolus, nucleus, phagocytic cup, plasma membrane protein binding, structural molecule activity Human CDC45 HPA UniProtKB {GO:0005515=PMID:17887956, GO:0005813=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000084=Reactome:REACT_899, GO:0006260=Reactome:REACT_6769, GO:0006271=Reactome:REACT_932, GO:0005737=GO_REF:0000039, GO:0000082=Reactome:REACT_1783, GO:0000083=Reactome:REACT_683, GO:0006270=GO_REF:0000002, GO:0000076=PMID:9660782, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_22145, GO:0000278=Reactome:REACT_152} O75419 Cell division control protein 45 homolog protein 20101115 {GO:0005515=IPI, GO:0005813=IDA, GO:0005634=IDA, GO:0000084=TAS, GO:0006260=TAS, GO:0006271=TAS, GO:0005737=IEA, GO:0000082=TAS, GO:0000083=TAS, GO:0006270=IEA, GO:0000076=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS} DNA replication, DNA replication checkpoint, DNA replication initiation, DNA strand elongation involved in DNA replication, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, cell cycle checkpoint, mitotic cell cycle, regulation of transcription involved in G1/S phase of mitotic cell cycle centrosome, cytoplasm, nucleoplasm, nucleus protein binding Human CDC5L HPA UniProtKB {GO:0005515=PMID:20176811, GO:0000974=PMID:20176811, GO:0006355=GO_REF:0000029, GO:0003723=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0071013=PMID:11991638, GO:0003677=PMID:8917598, GO:0006351=GO_REF:0000037, GO:0007049=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0016607=PMID:16332694, GO:0000398=PMID:11991638, GO:0071987=PMID:20176811, GO:0003682=GO_REF:0000002} Q99459 Cell division cycle 5-like protein protein 20081203 {GO:0005515=IPI, GO:0000974=IDA, GO:0006355=NAS, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0071013=IDA, GO:0003677=NAS, GO:0006351=IEA, GO:0007049=IEA, GO:0005737=IEA, GO:0016607=IDA, GO:0000398=IC, GO:0071987=IDA, GO:0003682=IEA} cell cycle, mRNA splicing, via spliceosome, regulation of transcription, DNA-dependent, transcription, DNA-dependent Prp19 complex, catalytic step 2 spliceosome, cytoplasm, nuclear speck, nucleolus, nucleus DNA binding, RNA binding, WD40-repeat domain binding, chromatin binding, protein binding NOT Human CDC6 BHF-UCL UniProtKB {GO:0005515=PMID:21041660, GO:0008285=PMID:9566895, GO:0005634=PMID:21041660, GO:0000079=PMID:9566895, GO:0051233=PMID:21041660, GO:0005829=Reactome:REACT_1673, GO:0000084=Reactome:REACT_899, GO:0000082=Reactome:REACT_1783, GO:0005737=PMID:9566895, GO:0000083=Reactome:REACT_683, GO:0000166=PMID:8990175, GO:0019900=PMID:21041660, GO:0017111=GO_REF:0000002, GO:0005819=GO_REF:0000019, GO:0051984=PMID:21041660, GO:0007089=PMID:9566895, GO:0005524=GO_REF:0000037, GO:0006260=Reactome:REACT_6769, GO:0007067=GO_REF:0000037, GO:0000922=PMID:21041660, GO:0003682=GO_REF:0000019, GO:0000076=PMID:9566895, GO:0000075=Reactome:REACT_1538, GO:0090007=PMID:21041660, GO:0005654=Reactome:REACT_111167, GO:0008156=PMID:9566895, GO:0000278=Reactome:REACT_152, GO:0051301=GO_REF:0000037} Q99741 Cell division control protein 6 homolog protein 20110202 {GO:0005515=IPI, GO:0008285=TAS, GO:0005634=IDA, GO:0000079=TAS, GO:0051233=IDA, GO:0005829=TAS, GO:0000084=TAS, GO:0000082=TAS, GO:0005737=TAS, GO:0000083=TAS, GO:0000166=TAS, GO:0019900=IPI, GO:0017111=IEA, GO:0005819=IEA, GO:0051984=IDA, GO:0007089=TAS, GO:0005524=IEA, GO:0006260=TAS, GO:0007067=IEA, GO:0000922=IDA, GO:0003682=IEA, GO:0000076=TAS, GO:0000075=TAS, GO:0090007=IMP, GO:0005654=TAS, GO:0008156=TAS, GO:0000278=TAS, GO:0051301=IEA} DNA replication, DNA replication checkpoint, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, cell cycle checkpoint, cell division, mitosis, mitotic cell cycle, negative regulation of DNA replication, negative regulation of cell proliferation, positive regulation of chromosome segregation, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of mitotic anaphase, regulation of transcription involved in G1/S phase of mitotic cell cycle, traversing start control point of mitotic cell cycle cytoplasm, cytosol, nucleoplasm, nucleus, spindle, spindle midzone, spindle pole ATP binding, chromatin binding, kinase binding, nucleoside-triphosphatase activity, nucleotide binding, protein binding Human CDC7 Reactome UniProtKB {GO:0008284=PMID:17102137, GO:0033261=PMID:17102137, GO:0005634=PMID:9250678, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0006260=Reactome:REACT_6769, GO:0005737=PMID:9250678, GO:0000082=Reactome:REACT_1783, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000037, GO:0016301=PMID:9250678, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_6750, GO:0000278=Reactome:REACT_152, GO:0051301=GO_REF:0000037} O00311 Cell division cycle 7-related protein kinase protein 20130213 {GO:0008284=IMP, GO:0033261=IMP, GO:0005634=IDA, GO:0005524=IEA, GO:0046872=IEA, GO:0006260=TAS, GO:0005737=IDA, GO:0000082=TAS, GO:0004672=IEA, GO:0004674=IEA, GO:0016301=IDA, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0051301=IEA} DNA replication, G1/S transition of mitotic cell cycle, cell cycle checkpoint, cell division, mitotic cell cycle, positive regulation of cell proliferation, regulation of S phase cytoplasm, nucleoplasm, nucleus ATP binding, kinase activity, metal ion binding, protein kinase activity, protein serine/threonine kinase activity Human CDC73 IntAct UniProtKB {GO:0005515=PMID:20541477, GO:0006378=PMID:21329879, GO:0033523=PMID:16307923, GO:0008285=PMID:16989776, GO:0000993=PMID:15923622, GO:0050680=PMID:18987311, GO:0048147=PMID:18987311, GO:0030177=PMID:16630820, GO:0005634=PMID:15923622, GO:2000134=PMID:16989776, GO:0045749=PMID:15923622, GO:0001711=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0007049=GO_REF:0000037, GO:0071222=GO_REF:0000024, GO:0045638=PMID:20541477, GO:0045944=PMID:20178742, GO:0019827=GO_REF:0000024, GO:0032968=PMID:20178742, GO:0016593=PMID:20178742, GO:0016055=GO_REF:0000037, GO:0010390=PMID:16307923, GO:0031442=PMID:19136632} Q6P1J9 Parafibromin protein 20130415 {GO:0005515=IPI, GO:0006378=IMP, GO:0033523=IDA, GO:0008285=IDA, GO:0000993=IDA, GO:0050680=IMP, GO:0048147=IMP, GO:0030177=IDA, GO:0005634=IDA, GO:2000134=IDA, GO:0045749=IMP, GO:0001711=ISS, GO:0006351=IEA, GO:0007049=IEA, GO:0071222=ISS, GO:0045638=IDA, GO:0045944=IDA, GO:0019827=ISS, GO:0032968=IDA, GO:0016593=IDA, GO:0016055=IEA, GO:0010390=IDA, GO:0031442=IMP} Wnt receptor signaling pathway, cell cycle, cellular response to lipopolysaccharide, endodermal cell fate commitment, histone H2B ubiquitination, histone monoubiquitination, mRNA polyadenylation, negative regulation of G1/S transition of mitotic cell cycle, negative regulation of S phase of mitotic cell cycle, negative regulation of cell proliferation, negative regulation of epithelial cell proliferation, negative regulation of fibroblast proliferation, negative regulation of myeloid cell differentiation, positive regulation of Wnt receptor signaling pathway, positive regulation of mRNA 3'-end processing, positive regulation of transcription elongation from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter, stem cell maintenance, transcription, DNA-dependent Cdc73/Paf1 complex, nucleus RNA polymerase II core binding, protein binding Human UniProtKB:Q03164 CDCA2 HPA UniProtKB {GO:0007067=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0051301=GO_REF:0000037} Q69YH5 Cell division cycle-associated protein 2 protein 20101115 {GO:0007067=IEA, GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0051301=IEA} cell division, mitosis cytoplasm, nucleolus, nucleus Human CDCA3 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0007067=GO_REF:0000037, GO:0016567=GO_REF:0000041, GO:0005575=GO_REF:0000015, GO:0005829=GO_REF:0000039, GO:0051301=GO_REF:0000037} Q99618 Cell division cycle-associated protein 3 protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0007067=IEA, GO:0016567=IEA, GO:0005575=ND, GO:0005829=IEA, GO:0051301=IEA} biological_process, cell division, mitosis, protein ubiquitination cellular_component, cytosol molecular_function Human CDCA4 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039} Q9BXL8 Cell division cycle-associated protein 4 protein 20130413 {GO:0005634=IEA} nucleus Human UniProtKB-SubCell:SL-0191 CDCA5 HPA UniProtKB {GO:0005515=PMID:21111234, GO:0007076=PMID:15837422, GO:0000236=Reactome:REACT_682, GO:0000790=GO_REF:0000024, GO:0005886=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0071922=PMID:17349791, GO:0005829=Reactome:REACT_150267, GO:0006302=PMID:17349791, GO:0000084=Reactome:REACT_899, GO:0005737=GO_REF:0000024, GO:0000082=PMID:15837422, GO:0000087=Reactome:REACT_910, GO:0005694=Reactome:REACT_150454, GO:0005730=GO_REF:0000052, GO:0051329=GO_REF:0000024, GO:0007067=PMID:15837422, GO:0008278=PMID:17349791, GO:0003682=PMID:15837422, GO:0005654=Reactome:REACT_150445, GO:0007080=PMID:15837422, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0000775=Reactome:REACT_150445, GO:0051301=GO_REF:0000037, GO:0007064=PMID:17349791} Q96FF9 Sororin protein 20101115 {GO:0005515=IPI, GO:0007076=IMP, GO:0000236=TAS, GO:0000790=ISS, GO:0005886=IDA, GO:0005634=IDA, GO:0071922=IMP, GO:0005829=TAS, GO:0006302=IMP, GO:0000084=TAS, GO:0005737=ISS, GO:0000082=IDA, GO:0000087=TAS, GO:0005694=TAS, GO:0005730=IDA, GO:0051329=ISS, GO:0007067=IDA, GO:0008278=IDA, GO:0003682=TAS, GO:0005654=TAS, GO:0007080=IMP, GO:0000278=TAS, GO:0000090=TAS, GO:0000775=TAS, GO:0051301=IEA, GO:0007064=IMP} G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, S phase of mitotic cell cycle, cell division, double-strand break repair, interphase of mitotic cell cycle, mitosis, mitotic anaphase, mitotic cell cycle, mitotic chromosome condensation, mitotic metaphase plate congression, mitotic prometaphase, mitotic sister chromatid cohesion, regulation of cohesin localization to chromatin chromosome, chromosome, centromeric region, cohesin complex, cytoplasm, cytosol, nuclear chromatin, nucleolus, nucleoplasm, nucleus, plasma membrane chromatin binding, protein binding Human CDCA7 MGI UniProtKB {GO:0006355=GO_REF:0000037, GO:0042127=PMID:11598121, GO:0005634=PMID:11598121, GO:0006351=GO_REF:0000037, GO:0051301=GO_REF:0000038} Q9BWT1 Cell division cycle-associated protein 7 protein 20060111 {GO:0006355=IEA, GO:0042127=IDA, GO:0005634=IDA, GO:0006351=IEA, GO:0051301=IEA} cell division, regulation of cell proliferation, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus Human CDCA7L HPA UniProtKB {GO:0008284=PMID:15994933, GO:0006355=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037} Q96GN5 Cell division cycle-associated 7-like protein protein 20101115 {GO:0008284=IDA, GO:0006355=IEA, GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0006351=IEA} positive regulation of cell proliferation, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleolus, nucleus Human CDCA8 HPA UniProtKB {GO:0005515=PMID:18243099, GO:0000236=Reactome:REACT_682, GO:0051276=PMID:15260989, GO:0005825=GO_REF:0000052, GO:0010369=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005829=Reactome:REACT_150414, GO:0043234=PMID:16239925, GO:0032133=PMID:18591255, GO:0000089=PMID:15260989, GO:0000087=Reactome:REACT_910, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0000775=PMID:15260989, GO:0051301=GO_REF:0000037} Q53HL2 Borealin protein 20120912 {GO:0005515=IPI, GO:0000236=TAS, GO:0051276=IMP, GO:0005825=IDA, GO:0010369=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005829=TAS, GO:0043234=IDA, GO:0032133=IPI, GO:0000089=IMP, GO:0000087=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0000775=IDA, GO:0051301=IEA} M phase of mitotic cell cycle, cell division, chromosome organization, mitotic anaphase, mitotic cell cycle, mitotic metaphase, mitotic prometaphase chromocenter, chromosome passenger complex, chromosome, centromeric region, cytosol, half bridge of spindle pole body, nucleolus, nucleus, protein complex protein binding Human CDCP1 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q9H5V8 CUB domain-containing protein 1 protein 20130413 {GO:0005886=IEA, GO:0005576=IEA, GO:0016021=IEA} extracellular region, integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 CDH1 HPA UniProtKB {GO:0005802=PMID:17620337, GO:0005515=PMID:20086044, GO:0030054=PMID:19038973, GO:0008013=PMID:17620337, GO:0007605=GO_REF:0000019, GO:0016342=PMID:18593713, GO:0042993=PMID:16338932, GO:0031175=GO_REF:0000019, GO:2000008=GO_REF:0000019, GO:0016337=PMID:16338932, GO:0070830=GO_REF:0000019, GO:0051260=GO_REF:0000019, GO:0050839=PMID:16338932, GO:0071285=PMID:12937339, GO:0022408=PMID:19653274, GO:0005794=GO_REF:0000039, GO:0009986=GO_REF:0000019, GO:0045295=PMID:1639850, GO:0019903=GO_REF:0000019, GO:0034329=Reactome:REACT_20676, GO:0005509=GO_REF:0000002, GO:0019904=GO_REF:0000019, GO:0030506=PMID:17620337, GO:0009636=GO_REF:0000019, GO:0007416=GO_REF:0000019, GO:0045216=Reactome:REACT_19331, GO:0043281=GO_REF:0000019, GO:0033561=GO_REF:0000019, GO:0050776=Reactome:REACT_11152, GO:0009898=PMID:20189993, GO:0045893=PMID:16338932, GO:0005925=GO_REF:0000052, GO:0019538=GO_REF:0000019, GO:0034332=Reactome:REACT_19195, GO:0048471=PMID:16338932, GO:0005886=GO_REF:0000052, GO:0060693=GO_REF:0000019, GO:0021983=GO_REF:0000019, GO:0015629=PMID:16338932, GO:0006921=Reactome:REACT_995, GO:0016323=GO_REF:0000019, GO:0043296=PMID:10460003, GO:0071681=PMID:10868478, GO:0005737=GO_REF:0000052, GO:0005913=PMID:20086044, GO:0071230=GO_REF:0000019, GO:0090102=GO_REF:0000019, GO:0043679=GO_REF:0000019, GO:0060662=GO_REF:0000019, GO:0007156=GO_REF:0000002, GO:0043220=GO_REF:0000019, GO:0016235=GO_REF:0000052, GO:0042493=GO_REF:0000019, GO:0045177=GO_REF:0000019, GO:0006915=Reactome:REACT_578, GO:0001829=GO_REF:0000019, GO:0072659=PMID:17620337, GO:0016328=PMID:17620337, GO:0032794=PMID:20116244, GO:0033268=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0043219=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0005768=GO_REF:0000039} Q9UII8 E-Cad/CTF3 protein 20080818 {GO:0005802=IMP, GO:0005515=IPI, GO:0030054=IDA, GO:0008013=IDA, GO:0007605=IEA, GO:0016342=IDA, GO:0042993=IDA, GO:0031175=IEA, GO:2000008=IEA, GO:0016337=IDA, GO:0070830=IEA, GO:0051260=IEA, GO:0050839=NAS, GO:0071285=IDA, GO:0022408=IMP, GO:0005794=IEA, GO:0009986=IEA, GO:0045295=IPI, GO:0019903=IEA, GO:0034329=TAS, GO:0005509=IEA, GO:0019904=IEA, GO:0030506=IPI, GO:0009636=IEA, GO:0007416=IEA, GO:0045216=TAS, GO:0043281=IEA, GO:0033561=IEA, GO:0050776=TAS, GO:0009898=IDA, GO:0045893=IDA, GO:0005925=IDA, GO:0019538=IEA, GO:0034332=TAS, GO:0048471=IDA, GO:0005886=IDA, GO:0060693=IEA, GO:0021983=IEA, GO:0015629=IDA, GO:0006921=TAS, GO:0016323=IEA, GO:0043296=IDA, GO:0071681=IDA, GO:0005737=IDA, GO:0005913=IDA, GO:0071230=IEA, GO:0090102=IEA, GO:0043679=IEA, GO:0060662=IEA, GO:0007156=IEA, GO:0043220=IEA, GO:0016235=IDA, GO:0042493=IEA, GO:0045177=IEA, GO:0006915=TAS, GO:0001829=IEA, GO:0072659=IDA, GO:0016328=IDA, GO:0032794=IPI, GO:0033268=IEA, GO:0016020=IEA, GO:0043219=IEA, GO:0016021=IEA, GO:0005768=IEA} adherens junction organization, apoptotic process, cell junction assembly, cell-cell adhesion, cell-cell junction organization, cellular component disassembly involved in execution phase of apoptosis, cellular response to amino acid stimulus, cellular response to indole-3-methanol, cellular response to lithium ion, cochlea development, homophilic cell adhesion, negative regulation of cell-cell adhesion, neuron projection development, pituitary gland development, positive regulation of transcription factor import into nucleus, positive regulation of transcription, DNA-dependent, protein homooligomerization, protein localization to plasma membrane, protein metabolic process, regulation of branching involved in salivary gland morphogenesis, regulation of cysteine-type endopeptidase activity involved in apoptotic process, regulation of immune response, regulation of protein localization to cell surface, regulation of water loss via skin, response to drug, response to toxic substance, salivary gland cavitation, sensory perception of sound, synapse assembly, tight junction assembly, trophectodermal cell differentiation Golgi apparatus, Schmidt-Lanterman incisure, actin cytoskeleton, aggresome, apical junction complex, apical part of cell, axon terminus, basolateral plasma membrane, catenin complex, cell junction, cell surface, cell-cell adherens junction, cytoplasm, endosome, focal adhesion, integral to membrane, internal side of plasma membrane, lateral loop, lateral plasma membrane, membrane, node of Ranvier, perinuclear region of cytoplasm, plasma membrane, trans-Golgi network GTPase activating protein binding, ankyrin binding, beta-catenin binding, calcium ion binding, cell adhesion molecule binding, gamma-catenin binding, protein binding, protein domain specific binding, protein phosphatase binding Human CDH10 Reactome UniProtKB {GO:0016337=PMID:10861224, GO:0005886=Reactome:REACT_19416, GO:0034329=Reactome:REACT_20676, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000029, GO:0007156=GO_REF:0000029, GO:0045216=Reactome:REACT_19331, GO:0034332=Reactome:REACT_19195} Q9Y6N8 Cadherin-10 protein 20130228 {GO:0016337=NAS, GO:0005886=TAS, GO:0034329=TAS, GO:0005509=IEA, GO:0016021=NAS, GO:0007156=NAS, GO:0045216=TAS, GO:0034332=TAS} adherens junction organization, cell junction assembly, cell-cell adhesion, cell-cell junction organization, homophilic cell adhesion integral to membrane, plasma membrane calcium ion binding Human CDH11 Reactome UniProtKB {GO:0001501=PMID:8163513, GO:0016337=GO_REF:0000029, GO:0001503=PMID:8163513, GO:0005886=Reactome:REACT_19416, GO:0034329=Reactome:REACT_20676, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000029, GO:0007155=PMID:8163513, GO:0007156=GO_REF:0000029, GO:0045216=Reactome:REACT_19331, GO:0034332=Reactome:REACT_19195} P55287 Cadherin-11 protein 20130228 {GO:0001501=TAS, GO:0016337=NAS, GO:0001503=NAS, GO:0005886=TAS, GO:0034329=TAS, GO:0005509=IEA, GO:0016021=NAS, GO:0007155=TAS, GO:0007156=NAS, GO:0045216=TAS, GO:0034332=TAS} adherens junction organization, cell adhesion, cell junction assembly, cell-cell adhesion, cell-cell junction organization, homophilic cell adhesion, ossification, skeletal system development integral to membrane, plasma membrane calcium ion binding Human CDH12 Reactome UniProtKB {GO:0016337=GO_REF:0000029, GO:0005886=Reactome:REACT_19416, GO:0034329=Reactome:REACT_20676, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000029, GO:0007156=GO_REF:0000029, GO:0045216=Reactome:REACT_19331, GO:0034332=Reactome:REACT_19195} P55289 Cadherin-12 protein 20130228 {GO:0016337=NAS, GO:0005886=TAS, GO:0034329=TAS, GO:0005509=IEA, GO:0016021=NAS, GO:0007156=NAS, GO:0045216=TAS, GO:0034332=TAS} adherens junction organization, cell junction assembly, cell-cell adhesion, cell-cell junction organization, homophilic cell adhesion integral to membrane, plasma membrane calcium ion binding Human CDH13 BHF-UCL UniProtKB {GO:0043005=PMID:10737605, GO:0008285=PMID:10737605, GO:0005886=PMID:10737605, GO:0030032=PMID:15703273, GO:0002040=PMID:16873731, GO:0031225=GO_REF:0000037, GO:0007266=PMID:15703273, GO:0005615=PMID:16873731, GO:0050850=PMID:16013438, GO:0050927=PMID:16013438, GO:0016339=PMID:10601632, GO:0005737=PMID:10737605, GO:0030100=PMID:17573778, GO:0045944=PMID:16099944, GO:0051668=PMID:17573778, GO:0007156=PMID:10601632, GO:0071813=PMID:11027617, GO:0030335=PMID:14729458, GO:0045296=PMID:10601632, GO:0034329=Reactome:REACT_20676, GO:0055100=GO_REF:0000024, GO:0005509=GO_REF:0000002, GO:0030169=PMID:16013438, GO:0043616=PMID:15816843, GO:0048661=PMID:15364621, GO:0045216=Reactome:REACT_19331, GO:0042058=PMID:17573778, GO:0016601=PMID:15703273, GO:0007162=PMID:14729458, GO:0055096=PMID:16013438, GO:0001938=PMID:15364621, GO:0043542=PMID:14729458, GO:0005901=PMID:9650591, GO:0001954=PMID:17573778, GO:0034332=Reactome:REACT_19195} P55290 Cadherin-13 protein 20071113 {GO:0043005=IDA, GO:0008285=IDA, GO:0005886=IDA, GO:0030032=IDA, GO:0002040=IDA, GO:0031225=IEA, GO:0007266=IMP, GO:0005615=IDA, GO:0050850=IDA, GO:0050927=IDA, GO:0016339=IDA, GO:0005737=IDA, GO:0030100=IMP, GO:0045944=IMP, GO:0051668=IMP, GO:0007156=IDA, GO:0071813=IDA, GO:0030335=IDA, GO:0045296=IDA, GO:0034329=TAS, GO:0055100=ISS, GO:0005509=IEA, GO:0030169=IDA, GO:0043616=IDA, GO:0048661=IMP, GO:0045216=TAS, GO:0042058=IMP, GO:0016601=IMP, GO:0007162=IDA, GO:0055096=IDA, GO:0001938=IMP, GO:0043542=IDA, GO:0005901=IDA, GO:0001954=IMP, GO:0034332=TAS} Rac protein signal transduction, Rho protein signal transduction, adherens junction organization, calcium-dependent cell-cell adhesion, cell junction assembly, cell-cell junction organization, endothelial cell migration, homophilic cell adhesion, keratinocyte proliferation, lamellipodium assembly, localization within membrane, low-density lipoprotein particle mediated signaling, negative regulation of cell adhesion, negative regulation of cell proliferation, positive regulation of calcium-mediated signaling, positive regulation of cell migration, positive regulation of cell-matrix adhesion, positive regulation of endothelial cell proliferation, positive regulation of positive chemotaxis, positive regulation of smooth muscle cell proliferation, positive regulation of transcription from RNA polymerase II promoter, regulation of endocytosis, regulation of epidermal growth factor receptor signaling pathway, sprouting angiogenesis anchored to membrane, caveola, cytoplasm, extracellular space, neuron projection, plasma membrane adiponectin binding, cadherin binding, calcium ion binding, lipoprotein particle binding, low-density lipoprotein particle binding Human CDH15 Reactome UniProtKB {GO:0042692=Reactome:REACT_21303, GO:0051149=Reactome:REACT_21402, GO:0031594=GO_REF:0000019, GO:0005886=Reactome:REACT_21371, GO:0034329=Reactome:REACT_20676, GO:0005901=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007155=PMID:9545347, GO:0007156=GO_REF:0000002, GO:0045216=Reactome:REACT_19331, GO:0034332=Reactome:REACT_19195} P55291 Cadherin-15 protein 20130301 {GO:0042692=TAS, GO:0051149=TAS, GO:0031594=IEA, GO:0005886=TAS, GO:0034329=TAS, GO:0005901=IEA, GO:0005509=IEA, GO:0016021=IEA, GO:0007155=TAS, GO:0007156=IEA, GO:0045216=TAS, GO:0034332=TAS} adherens junction organization, cell adhesion, cell junction assembly, cell-cell junction organization, homophilic cell adhesion, muscle cell differentiation, positive regulation of muscle cell differentiation caveola, integral to membrane, neuromuscular junction, plasma membrane calcium ion binding Human CDH16 PINC UniProtKB {GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007155=PMID:9721215, GO:0007156=GO_REF:0000002} O75309 Cadherin-16 protein 20030904 {GO:0005886=IEA, GO:0005509=IEA, GO:0016021=IEA, GO:0007155=TAS, GO:0007156=IEA} cell adhesion, homophilic cell adhesion integral to membrane, plasma membrane calcium ion binding Human CDH17 PINC UniProtKB {GO:0016339=GO_REF:0000019, GO:0005215=PMID:8153632, GO:0016323=GO_REF:0000019, GO:0005427=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0005886=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0006810=PMID:8153632, GO:0016021=GO_REF:0000037, GO:0007155=PMID:8153632, GO:0007156=GO_REF:0000019} Q12864 Cadherin-17 protein 20030904 {GO:0016339=IEA, GO:0005215=TAS, GO:0016323=IEA, GO:0005427=IEA, GO:0016020=IEA, GO:0005886=IEA, GO:0005509=IEA, GO:0006810=NAS, GO:0016021=IEA, GO:0007155=TAS, GO:0007156=IEA} calcium-dependent cell-cell adhesion, cell adhesion, homophilic cell adhesion, transport basolateral plasma membrane, integral to membrane, membrane, plasma membrane calcium ion binding, proton-dependent oligopeptide secondary active transmembrane transporter activity, transporter activity Human CDH18 Reactome UniProtKB {GO:0005886=Reactome:REACT_19416, GO:0034329=Reactome:REACT_20676, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000002, GO:0045216=Reactome:REACT_19331, GO:0034332=Reactome:REACT_19195} Q13634 Cadherin-18 protein 20130228 {GO:0005886=TAS, GO:0034329=TAS, GO:0005509=IEA, GO:0016021=IEA, GO:0007156=IEA, GO:0045216=TAS, GO:0034332=TAS} adherens junction organization, cell junction assembly, cell-cell junction organization, homophilic cell adhesion integral to membrane, plasma membrane calcium ion binding Human CDH19 UniProtKB UniProtKB {GO:0016337=GO_REF:0000029, GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000029, GO:0007156=GO_REF:0000029} Q9H159 Cadherin-19 protein 20021106 {GO:0016337=NAS, GO:0005886=IEA, GO:0005509=IEA, GO:0016021=NAS, GO:0007156=NAS} cell-cell adhesion, homophilic cell adhesion integral to membrane, plasma membrane calcium ion binding Human CDH2 BHF-UCL UniProtKB {GO:0005886=Reactome:REACT_21371, GO:0008013=PMID:16344550, GO:0048514=GO_REF:0000019, GO:0016342=PMID:7650039, GO:0045202=GO_REF:0000019, GO:0016339=GO_REF:0000019, GO:0005916=GO_REF:0000019, GO:0042692=Reactome:REACT_21303, GO:0005913=PMID:19101069, GO:0005543=GO_REF:0000002, GO:0014704=GO_REF:0000024, GO:0005911=PMID:7650039, GO:0007155=PMID:2384753, GO:0007156=GO_REF:0000019, GO:0090090=GO_REF:0000019, GO:0007157=GO_REF:0000019, GO:0045295=PMID:7650039, GO:0045294=PMID:7650039, GO:0019903=GO_REF:0000019, GO:0034329=Reactome:REACT_20676, GO:0005509=GO_REF:0000002, GO:0030027=GO_REF:0000019, GO:0045216=Reactome:REACT_19331, GO:0051149=Reactome:REACT_21402, GO:0016477=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0043410=GO_REF:0000019, GO:0051146=GO_REF:0000019, GO:0034332=Reactome:REACT_19195} P19022 Cadherin-2 protein 20120521 {GO:0005886=TAS, GO:0008013=TAS, GO:0048514=IEA, GO:0016342=IDA, GO:0045202=IEA, GO:0016339=IEA, GO:0005916=IEA, GO:0042692=TAS, GO:0005913=IDA, GO:0005543=IEA, GO:0014704=ISS, GO:0005911=IDA, GO:0007155=TAS, GO:0007156=IEA, GO:0090090=IEA, GO:0007157=IEA, GO:0045295=IPI, GO:0045294=IPI, GO:0019903=IEA, GO:0034329=TAS, GO:0005509=IEA, GO:0030027=IEA, GO:0045216=TAS, GO:0051149=TAS, GO:0016477=IEA, GO:0016020=IEA, GO:0016021=IEA, GO:0043410=IEA, GO:0051146=IEA, GO:0034332=TAS} adherens junction organization, blood vessel morphogenesis, calcium-dependent cell-cell adhesion, cell adhesion, cell junction assembly, cell migration, cell-cell junction organization, heterophilic cell-cell adhesion, homophilic cell adhesion, muscle cell differentiation, negative regulation of canonical Wnt receptor signaling pathway, positive regulation of MAPK cascade, positive regulation of muscle cell differentiation, striated muscle cell differentiation catenin complex, cell-cell adherens junction, cell-cell junction, fascia adherens, integral to membrane, intercalated disc, lamellipodium, membrane, plasma membrane, synapse alpha-catenin binding, beta-catenin binding, calcium ion binding, gamma-catenin binding, phospholipid binding, protein phosphatase binding Human UniProtKB:P15116 CDH22 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000002} Q9UJ99 Cadherin-22 protein 20130413 {GO:0005886=IEA, GO:0005509=IEA, GO:0016021=IEA, GO:0007156=IEA} homophilic cell adhesion integral to membrane, plasma membrane calcium ion binding Human UniProtKB-SubCell:SL-0039 CDH23 HGNC UniProtKB {GO:0005515=PMID:12485990, GO:0005886=GO_REF:0000039, GO:0007605=PMID:15537665, GO:0051480=PMID:17234811, GO:0005509=GO_REF:0000002, GO:0032420=PMID:12485990, GO:0045494=PMID:16679490, GO:0016339=PMID:11138009, GO:0016020=PMID:11138009, GO:0006816=PMID:17234811, GO:0050957=PMID:16679490, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000002, GO:0050896=GO_REF:0000037, GO:0050953=PMID:16679490} Q9H251 Cadherin-23 protein 20071018 {GO:0005515=IPI, GO:0005886=IEA, GO:0007605=IMP, GO:0051480=IMP, GO:0005509=IEA, GO:0032420=ISS, GO:0045494=IMP, GO:0016339=NAS, GO:0016020=NAS, GO:0006816=IMP, GO:0050957=IMP, GO:0016021=IEA, GO:0007156=IEA, GO:0050896=IEA, GO:0050953=IMP} calcium ion transport, calcium-dependent cell-cell adhesion, cytosolic calcium ion homeostasis, equilibrioception, homophilic cell adhesion, photoreceptor cell maintenance, response to stimulus, sensory perception of light stimulus, sensory perception of sound integral to membrane, membrane, plasma membrane, stereocilium calcium ion binding, protein binding Human CDH24 Reactome UniProtKB {GO:0016337=PMID:12734196, GO:0005886=Reactome:REACT_19416, GO:0005911=PMID:12734196, GO:0034329=Reactome:REACT_20676, GO:0005509=PMID:12734196, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000002, GO:0045216=Reactome:REACT_19331, GO:0034332=Reactome:REACT_19195} Q86UP0 Cadherin-24 protein 20130228 {GO:0016337=IDA, GO:0005886=TAS, GO:0005911=IDA, GO:0034329=TAS, GO:0005509=IDA, GO:0016021=IEA, GO:0007156=IEA, GO:0045216=TAS, GO:0034332=TAS} adherens junction organization, cell junction assembly, cell-cell adhesion, cell-cell junction organization, homophilic cell adhesion cell-cell junction, integral to membrane, plasma membrane calcium ion binding Human CDH3 Reactome UniProtKB {GO:0005913=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0005886=Reactome:REACT_19416, GO:0034329=Reactome:REACT_20676, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007155=PMID:2793940, GO:0007601=GO_REF:0000037, GO:0007156=GO_REF:0000002, GO:0045216=Reactome:REACT_19331, GO:0050896=GO_REF:0000037, GO:0034332=Reactome:REACT_19195} P22223 Cadherin-3 protein 20130228 {GO:0005913=IEA, GO:0016020=IEA, GO:0005886=TAS, GO:0034329=TAS, GO:0005509=IEA, GO:0016021=IEA, GO:0007155=TAS, GO:0007601=IEA, GO:0007156=IEA, GO:0045216=TAS, GO:0050896=IEA, GO:0034332=TAS} adherens junction organization, cell adhesion, cell junction assembly, cell-cell junction organization, homophilic cell adhesion, response to stimulus, visual perception cell-cell adherens junction, integral to membrane, membrane, plasma membrane calcium ion binding Human CDH4 HPA UniProtKB {GO:0005886=GO_REF:0000052, GO:0007411=GO_REF:0000019, GO:0005887=GO_REF:0000019, GO:0034329=Reactome:REACT_20676, GO:0005509=GO_REF:0000002, GO:0045773=GO_REF:0000019, GO:0007155=PMID:2059658, GO:0007156=GO_REF:0000019, GO:0045216=Reactome:REACT_19331, GO:0007157=GO_REF:0000019, GO:0034332=Reactome:REACT_19195} P55283 Cadherin-4 protein 20090616 {GO:0005886=IDA, GO:0007411=IEA, GO:0005887=IEA, GO:0034329=TAS, GO:0005509=IEA, GO:0045773=IEA, GO:0007155=TAS, GO:0007156=IEA, GO:0045216=TAS, GO:0007157=IEA, GO:0034332=TAS} adherens junction organization, axon guidance, cell adhesion, cell junction assembly, cell-cell junction organization, heterophilic cell-cell adhesion, homophilic cell adhesion, positive regulation of axon extension integral to plasma membrane, plasma membrane calcium ion binding Human CDH5 BHF-UCL UniProtKB {GO:0005515=PMID:20332120, GO:0008285=GO_REF:0000019, GO:0008013=PMID:18287330, GO:0005886=Reactome:REACT_19416, GO:0034329=Reactome:REACT_20676, GO:0019903=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0005102=PMID:12088286, GO:2000114=PMID:20332120, GO:0045216=Reactome:REACT_19331, GO:0044325=PMID:19996314, GO:0071944=GO_REF:0000019, GO:0016020=PMID:9219219, GO:0005911=PMID:19996314, GO:0005923=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000002, GO:0001955=GO_REF:0000019, GO:0034332=Reactome:REACT_19195} P33151 Cadherin-5 protein 20100825 {GO:0005515=IPI, GO:0008285=IEA, GO:0008013=IPI, GO:0005886=TAS, GO:0034329=TAS, GO:0019903=IEA, GO:0005509=IEA, GO:0005102=IPI, GO:2000114=IMP, GO:0045216=TAS, GO:0044325=IPI, GO:0071944=IEA, GO:0016020=TAS, GO:0005911=IDA, GO:0005923=IEA, GO:0016021=IEA, GO:0007156=IEA, GO:0001955=IEA, GO:0034332=TAS} adherens junction organization, blood vessel maturation, cell junction assembly, cell-cell junction organization, homophilic cell adhesion, negative regulation of cell proliferation, regulation of establishment of cell polarity cell periphery, cell-cell junction, integral to membrane, membrane, plasma membrane, tight junction beta-catenin binding, calcium ion binding, ion channel binding, protein binding, protein phosphatase binding, receptor binding Human UniProtKB:Q9UBN4 CDH6 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0034329=Reactome:REACT_20676, GO:0005509=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0016021=GO_REF:0000037, GO:0007155=PMID:7743525, GO:0007156=GO_REF:0000002, GO:0045216=Reactome:REACT_19331, GO:0034332=Reactome:REACT_19195} P55285 Cadherin-6 protein 20101115 {GO:0005737=IDA, GO:0005886=IDA, GO:0034329=TAS, GO:0005509=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0016021=IEA, GO:0007155=TAS, GO:0007156=IEA, GO:0045216=TAS, GO:0034332=TAS} adherens junction organization, cell adhesion, cell junction assembly, cell-cell junction organization, homophilic cell adhesion cytoplasm, integral to membrane, nucleolus, nucleus, plasma membrane calcium ion binding Human CDH7 Reactome UniProtKB {GO:0016337=PMID:10861224, GO:0005886=Reactome:REACT_19416, GO:0034329=Reactome:REACT_20676, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000029, GO:0007156=GO_REF:0000029, GO:0045216=Reactome:REACT_19331, GO:0034332=Reactome:REACT_19195} Q9ULB5 Cadherin-7 protein 20130228 {GO:0016337=NAS, GO:0005886=TAS, GO:0034329=TAS, GO:0005509=IEA, GO:0016021=NAS, GO:0007156=NAS, GO:0045216=TAS, GO:0034332=TAS} adherens junction organization, cell junction assembly, cell-cell adhesion, cell-cell junction organization, homophilic cell adhesion integral to membrane, plasma membrane calcium ion binding Human CDH8 Reactome UniProtKB {GO:0005886=Reactome:REACT_19416, GO:0034329=Reactome:REACT_20676, GO:0009409=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0035249=GO_REF:0000019, GO:0043679=GO_REF:0000019, GO:0043083=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007155=PMID:2059658, GO:0007156=GO_REF:0000002, GO:0045216=Reactome:REACT_19331, GO:0034332=Reactome:REACT_19195} P55286 Cadherin-8 protein 20130228 {GO:0005886=TAS, GO:0034329=TAS, GO:0009409=IEA, GO:0005509=IEA, GO:0035249=IEA, GO:0043679=IEA, GO:0043083=IEA, GO:0016021=IEA, GO:0007155=TAS, GO:0007156=IEA, GO:0045216=TAS, GO:0034332=TAS} adherens junction organization, cell adhesion, cell junction assembly, cell-cell junction organization, homophilic cell adhesion, response to cold, synaptic transmission, glutamatergic axon terminus, integral to membrane, plasma membrane, synaptic cleft calcium ion binding Human CDH9 Reactome UniProtKB {GO:0003674=GO_REF:0000015, GO:0016337=PMID:10861224, GO:0005886=Reactome:REACT_19416, GO:0034329=Reactome:REACT_20676, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000029, GO:0007156=GO_REF:0000029, GO:0045216=Reactome:REACT_19331, GO:0034332=Reactome:REACT_19195} Q9ULB4 Cadherin-9 protein 20130228 {GO:0003674=ND, GO:0016337=NAS, GO:0005886=TAS, GO:0034329=TAS, GO:0005509=IEA, GO:0016021=NAS, GO:0007156=NAS, GO:0045216=TAS, GO:0034332=TAS} adherens junction organization, cell junction assembly, cell-cell adhesion, cell-cell junction organization, homophilic cell adhesion integral to membrane, plasma membrane calcium ion binding, molecular_function Human CDHR1 ENSEMBL UniProtKB {GO:0005886=GO_REF:0000002, GO:0042622=GO_REF:0000019, GO:0005887=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000038, GO:0045494=GO_REF:0000019, GO:0007156=GO_REF:0000002} Q96JP9 Cadherin-related family member 1 protein 20130413 {GO:0005886=IEA, GO:0042622=IEA, GO:0005887=IEA, GO:0005509=IEA, GO:0016021=IEA, GO:0045494=IEA, GO:0007156=IEA} homophilic cell adhesion, photoreceptor cell maintenance integral to membrane, integral to plasma membrane, photoreceptor outer segment membrane, plasma membrane calcium ion binding Human Ensembl:ENSMUSP00000022337 CDHR2 UniProtKB UniProtKB {GO:0005515=PMID:12117771, GO:0030308=PMID:12117771, GO:0016324=GO_REF:0000039, GO:0030054=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0016021=PMID:12117771, GO:0007155=PMID:12117771, GO:0007156=GO_REF:0000002} Q9BYE9 Cadherin-related family member 2 protein 20050302 {GO:0005515=IPI, GO:0030308=IDA, GO:0016324=IEA, GO:0030054=IEA, GO:0005509=IEA, GO:0016021=IDA, GO:0007155=IDA, GO:0007156=IEA} cell adhesion, homophilic cell adhesion, negative regulation of cell growth apical plasma membrane, cell junction, integral to membrane calcium ion binding, protein binding Human CDIPT Reactome UniProtKB {GO:0030145=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0006661=Reactome:REACT_121000, GO:0043178=GO_REF:0000019, GO:0046341=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0008654=GO_REF:0000002, GO:0019992=GO_REF:0000019, GO:0016780=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0000139=GO_REF:0000039, GO:0005789=Reactome:REACT_121059, GO:0030246=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0016740=GO_REF:0000038, GO:0046474=Reactome:REACT_121401, GO:0003881=Reactome:REACT_121059} O14735 CDP-diacylglycerol--inositol 3-phosphatidyltransferase protein 20111102 {GO:0030145=IEA, GO:0005886=IEA, GO:0006661=TAS, GO:0043178=IEA, GO:0046341=IEA, GO:0044281=TAS, GO:0008654=IEA, GO:0019992=IEA, GO:0016780=IEA, GO:0016020=IEA, GO:0000139=IEA, GO:0005789=TAS, GO:0030246=IEA, GO:0016021=IEA, GO:0006644=TAS, GO:0016740=IEA, GO:0046474=TAS, GO:0003881=TAS} CDP-diacylglycerol metabolic process, glycerophospholipid biosynthetic process, phosphatidylinositol biosynthetic process, phospholipid biosynthetic process, phospholipid metabolic process, small molecule metabolic process Golgi membrane, endoplasmic reticulum membrane, integral to membrane, membrane, plasma membrane CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity, alcohol binding, carbohydrate binding, diacylglycerol binding, manganese ion binding, phosphotransferase activity, for other substituted phosphate groups, transferase activity Human CDK1 BHF-UCL UniProtKB {GO:0007077=Reactome:REACT_160255, GO:0060045=GO_REF:0000019, GO:0005515=PMID:21041660, GO:0000236=Reactome:REACT_682, GO:0014070=GO_REF:0000019, GO:0033160=GO_REF:0000019, GO:0070301=GO_REF:0000019, GO:0030261=GO_REF:0000019, GO:0034501=PMID:18195732, GO:0014075=GO_REF:0000019, GO:0051403=Reactome:REACT_21308, GO:0048678=GO_REF:0000019, GO:0002756=Reactome:REACT_6809, GO:0007173=Reactome:REACT_9417, GO:0007411=Reactome:REACT_18266, GO:0000165=Reactome:REACT_634, GO:0002755=Reactome:REACT_27215, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0005815=GO_REF:0000039, GO:0034134=Reactome:REACT_7980, GO:0030332=GO_REF:0000019, GO:0007569=GO_REF:0000019, GO:0045740=GO_REF:0000019, GO:0009636=GO_REF:0000019, GO:0030496=PMID:11069302, GO:0002224=Reactome:REACT_9020, GO:0045931=GO_REF:0000019, GO:0035173=GO_REF:0000019, GO:0006281=PMID:21655336, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0055015=GO_REF:0000019, GO:0030544=GO_REF:0000019, GO:0000075=Reactome:REACT_1538, GO:0035666=Reactome:REACT_25281, GO:0034166=Reactome:REACT_9027, GO:0005654=Reactome:REACT_150132, GO:0000278=Reactome:REACT_152, GO:0046688=GO_REF:0000019, GO:0034162=Reactome:REACT_9047, GO:0046686=GO_REF:0000019, GO:0051301=GO_REF:0000037, GO:0004693=Reactome:REACT_1627, GO:0008286=Reactome:REACT_498, GO:0007095=GO_REF:0000019, GO:0034142=Reactome:REACT_6894, GO:0007264=Reactome:REACT_12077, GO:0007098=PMID:19364923, GO:0045471=GO_REF:0000019, GO:0031100=GO_REF:0000019, GO:0007265=Reactome:REACT_12033, GO:0005634=GO_REF:0000052, GO:0031145=Reactome:REACT_6850, GO:0005829=Reactome:REACT_160217, GO:0005739=PMID:19917720, GO:0000187=Reactome:REACT_1482, GO:0005737=GO_REF:0000052, GO:0000186=Reactome:REACT_12005, GO:0000082=Reactome:REACT_1783, GO:0000083=Reactome:REACT_683, GO:0000088=Reactome:REACT_765, GO:0000086=Reactome:REACT_2203, GO:0000087=Reactome:REACT_910, GO:0005876=PMID:11069302, GO:0034138=Reactome:REACT_6783, GO:0014823=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0043066=PMID:11069302, GO:0042493=GO_REF:0000019, GO:0051437=Reactome:REACT_6904, GO:0006915=GO_REF:0000037, GO:0000226=PMID:21655336, GO:0005524=GO_REF:0000037, GO:0008353=PMID:12721286, GO:0051439=Reactome:REACT_6837, GO:0045995=PMID:21535261, GO:0006260=PMID:21655336, GO:0010628=GO_REF:0000019, GO:0014038=PMID:17200138, GO:0006461=GO_REF:0000019, GO:0004672=PMID:9001210, GO:0016477=PMID:17200138, GO:0004674=GO_REF:0000038, GO:0007344=PMID:21535261, GO:0034146=Reactome:REACT_9061} P06493 Cyclin-dependent kinase 1 protein 20110202 {GO:0007077=TAS, GO:0060045=IEA, GO:0005515=IPI, GO:0000236=TAS, GO:0014070=IEA, GO:0033160=IEA, GO:0070301=IEA, GO:0030261=IEA, GO:0034501=IDA, GO:0014075=IEA, GO:0051403=TAS, GO:0048678=IEA, GO:0002756=TAS, GO:0007173=TAS, GO:0007411=TAS, GO:0000165=TAS, GO:0002755=TAS, GO:0038124=TAS, GO:0038123=TAS, GO:0005815=IEA, GO:0034134=TAS, GO:0030332=IEA, GO:0007569=IEA, GO:0045740=IEA, GO:0009636=IEA, GO:0030496=IDA, GO:0002224=TAS, GO:0045931=IEA, GO:0035173=IEA, GO:0006281=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0055015=IEA, GO:0030544=IEA, GO:0000075=TAS, GO:0035666=TAS, GO:0034166=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0046688=IEA, GO:0034162=TAS, GO:0046686=IEA, GO:0051301=IEA, GO:0004693=TAS, GO:0008286=TAS, GO:0007095=IEA, GO:0034142=TAS, GO:0007264=TAS, GO:0007098=TAS, GO:0045471=IEA, GO:0031100=IEA, GO:0007265=TAS, GO:0005634=IDA, GO:0031145=TAS, GO:0005829=TAS, GO:0005739=TAS, GO:0000187=TAS, GO:0005737=IDA, GO:0000186=TAS, GO:0000082=TAS, GO:0000083=TAS, GO:0000088=TAS, GO:0000086=TAS, GO:0000087=TAS, GO:0005876=IDA, GO:0034138=TAS, GO:0014823=IEA, GO:0048011=TAS, GO:0043066=IDA, GO:0042493=IEA, GO:0051437=TAS, GO:0006915=IEA, GO:0000226=TAS, GO:0005524=IEA, GO:0008353=IDA, GO:0051439=TAS, GO:0045995=TAS, GO:0006260=TAS, GO:0010628=IEA, GO:0014038=TAS, GO:0006461=IEA, GO:0004672=NAS, GO:0016477=TAS, GO:0004674=IEA, GO:0007344=TAS, GO:0034146=TAS} DNA repair, DNA replication, G1/S transition of mitotic cell cycle, G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, MAPK cascade, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, Ras protein signal transduction, TRIF-dependent toll-like receptor signaling pathway, activation of MAPK activity, activation of MAPKK activity, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, apoptotic process, axon guidance, cell aging, cell cycle checkpoint, cell division, cell migration, cellular response to hydrogen peroxide, centrosome cycle, chromosome condensation, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, microtubule cytoskeleton organization, mitotic G2 DNA damage checkpoint, mitotic cell cycle, mitotic nuclear envelope disassembly, mitotic prometaphase, mitotic prophase, negative regulation of apoptotic process, neurotrophin TRK receptor signaling pathway, organ regeneration, positive regulation of DNA replication, positive regulation of cardiac muscle cell proliferation, positive regulation of gene expression, positive regulation of mitotic cell cycle, positive regulation of protein import into nucleus, translocation, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, pronuclear fusion, protein complex assembly, protein localization to kinetochore, regulation of Schwann cell differentiation, regulation of embryonic development, regulation of transcription involved in G1/S phase of mitotic cell cycle, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, response to activity, response to amine stimulus, response to axon injury, response to cadmium ion, response to copper ion, response to drug, response to ethanol, response to organic cyclic compound, response to toxic substance, small GTPase mediated signal transduction, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, ventricular cardiac muscle cell development cytoplasm, cytosol, microtubule organizing center, midbody, mitochondrion, nucleoplasm, nucleus, spindle microtubule ATP binding, Hsp70 protein binding, RNA polymerase II carboxy-terminal domain kinase activity, cyclin binding, cyclin-dependent protein serine/threonine kinase activity, histone kinase activity, protein binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB:Q99741 CDK10 UniProtKB UniProtKB {GO:0005515=PMID:22939624, GO:0008285=PMID:8208557, GO:0016301=GO_REF:0000038, GO:0004674=GO_REF:0000002, GO:0007089=PMID:8208557, GO:0005524=GO_REF:0000037, GO:0004693=GO_REF:0000003} Q9UHL7 Cyclin-dependent kinase related protein protein 20130413 {GO:0005515=IPI, GO:0008285=TAS, GO:0016301=IEA, GO:0004674=IEA, GO:0007089=TAS, GO:0005524=IEA, GO:0004693=IEA} negative regulation of cell proliferation, traversing start control point of mitotic cell cycle ATP binding, cyclin-dependent protein serine/threonine kinase activity, kinase activity, protein binding, protein serine/threonine kinase activity Human UniProtKB-KW:KW-0418 CDK11A HPA UniProtKB {GO:0007067=PMID:1639388, GO:0006355=PMID:9750192, GO:0005737=GO_REF:0000052, GO:0004672=PMID:9750192, GO:0004674=PMID:12501247, GO:0006915=PMID:9750192, GO:0006468=PMID:12501247, GO:0005634=GO_REF:0000052, GO:0050684=PMID:12501247, GO:0001558=PMID:10882096, GO:0005524=PMID:12501247, GO:0004693=GO_REF:0000003} Q9UQ88 Cyclin-dependent kinase 11A protein 20101115 {GO:0007067=NAS, GO:0006355=NAS, GO:0005737=IDA, GO:0004672=NAS, GO:0004674=IDA, GO:0006915=NAS, GO:0006468=IDA, GO:0005634=IDA, GO:0050684=IDA, GO:0001558=IEP, GO:0005524=IDA, GO:0004693=IEA} apoptotic process, mitosis, protein phosphorylation, regulation of cell growth, regulation of mRNA processing, regulation of transcription, DNA-dependent cytoplasm, nucleus ATP binding, cyclin-dependent protein serine/threonine kinase activity, protein kinase activity, protein serine/threonine kinase activity Human CDK11B HPA UniProtKB {GO:0005515=PMID:12624090, GO:0006355=PMID:9750192, GO:0008283=PMID:8195233, GO:0006915=PMID:9750192, GO:0005634=GO_REF:0000052, GO:0050684=PMID:12501247, GO:0005524=PMID:12501247, GO:0001558=PMID:10882096, GO:0005737=GO_REF:0000052, GO:0007067=PMID:1639388, GO:0004672=PMID:8195233, GO:0004674=PMID:12501247, GO:0006468=PMID:12501247, GO:0004693=GO_REF:0000003} P21127 Cyclin-dependent kinase 11B protein 20101115 {GO:0005515=IPI, GO:0006355=NAS, GO:0008283=TAS, GO:0006915=NAS, GO:0005634=IDA, GO:0050684=IDA, GO:0005524=IDA, GO:0001558=IEP, GO:0005737=IDA, GO:0007067=NAS, GO:0004672=TAS, GO:0004674=IDA, GO:0006468=IDA, GO:0004693=IEA} apoptotic process, cell proliferation, mitosis, protein phosphorylation, regulation of cell growth, regulation of mRNA processing, regulation of transcription, DNA-dependent cytoplasm, nucleus ATP binding, cyclin-dependent protein serine/threonine kinase activity, protein binding, protein kinase activity, protein serine/threonine kinase activity Human CDK12 HPA UniProtKB {GO:0006397=GO_REF:0000037, GO:0070816=PMID:20952539, GO:0008380=GO_REF:0000024, GO:0005515=PMID:12841360, GO:0019908=GO_REF:0000024, GO:0030332=PMID:22012619, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037, GO:0008353=PMID:20952539, GO:0002944=PMID:22012619, GO:0046777=PMID:11683387, GO:0004672=PMID:11683387, GO:0016607=PMID:11683387, GO:0043405=PMID:19651820, GO:0004674=GO_REF:0000002, GO:0004693=GO_REF:0000003} Q9NYV4 Cyclin-dependent kinase 12 protein 20101115 {GO:0006397=IEA, GO:0070816=IMP, GO:0008380=ISS, GO:0005515=IPI, GO:0019908=ISS, GO:0030332=IPI, GO:0005730=IDA, GO:0005634=IDA, GO:0005524=IEA, GO:0008353=IMP, GO:0002944=IPI, GO:0046777=IDA, GO:0004672=IDA, GO:0016607=IDA, GO:0043405=IMP, GO:0004674=IEA, GO:0004693=IEA} RNA splicing, mRNA processing, phosphorylation of RNA polymerase II C-terminal domain, protein autophosphorylation, regulation of MAP kinase activity cyclin K-CDK12 complex, nuclear cyclin-dependent protein kinase holoenzyme complex, nuclear speck, nucleolus, nucleus ATP binding, RNA polymerase II carboxy-terminal domain kinase activity, cyclin binding, cyclin-dependent protein serine/threonine kinase activity, protein binding, protein kinase activity, protein serine/threonine kinase activity Human CDK13 PINC UniProtKB {GO:0070816=PMID:20952539, GO:0030097=PMID:1731328, GO:0005515=PMID:16721827, GO:0007088=PMID:1731328, GO:0008284=PMID:1731328, GO:0019908=GO_REF:0000024, GO:0030332=PMID:22012619, GO:0007275=PMID:1731328, GO:0005524=GO_REF:0000037, GO:0008353=PMID:20952539, GO:0002945=PMID:22012619, GO:0004672=PMID:1731328, GO:0016607=PMID:16721827, GO:0019048=GO_REF:0000037, GO:0000380=GO_REF:0000024, GO:0004693=GO_REF:0000003} Q14004 Cyclin-dependent kinase 13 protein 20030904 {GO:0070816=IDA, GO:0030097=IMP, GO:0005515=IPI, GO:0007088=TAS, GO:0008284=TAS, GO:0019908=ISS, GO:0030332=IPI, GO:0007275=TAS, GO:0005524=IEA, GO:0008353=IDA, GO:0002945=IPI, GO:0004672=TAS, GO:0016607=IDA, GO:0019048=IEA, GO:0000380=ISS, GO:0004693=IEA} alternative mRNA splicing, via spliceosome, hemopoiesis, multicellular organismal development, phosphorylation of RNA polymerase II C-terminal domain, positive regulation of cell proliferation, regulation of mitosis, virus-host interaction cyclin K-CDK13 complex, nuclear cyclin-dependent protein kinase holoenzyme complex, nuclear speck ATP binding, RNA polymerase II carboxy-terminal domain kinase activity, cyclin binding, cyclin-dependent protein serine/threonine kinase activity, protein binding, protein kinase activity Human CDK14 HPA UniProtKB {GO:0005515=PMID:22939624, GO:0005886=PMID:19524571, GO:0030332=PMID:20059949, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037, GO:0060828=PMID:20059949, GO:0005829=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0004672=GO_REF:0000019, GO:0004674=GO_REF:0000002, GO:0000086=PMID:20059949, GO:0000308=PMID:20059949, GO:0016055=GO_REF:0000037, GO:0051301=GO_REF:0000037, GO:0004693=PMID:20059949} O94921 Cyclin-dependent kinase 14 protein 20090616 {GO:0005515=IPI, GO:0005886=IDA, GO:0030332=IPI, GO:0005634=IDA, GO:0005524=IEA, GO:0060828=IDA, GO:0005829=IEA, GO:0005737=IDA, GO:0004672=IEA, GO:0004674=IEA, GO:0000086=IDA, GO:0000308=IDA, GO:0016055=IEA, GO:0051301=IEA, GO:0004693=IMP} G2/M transition of mitotic cell cycle, Wnt receptor signaling pathway, cell division, regulation of canonical Wnt receptor signaling pathway cytoplasm, cytoplasmic cyclin-dependent protein kinase holoenzyme complex, cytosol, nucleus, plasma membrane ATP binding, cyclin binding, cyclin-dependent protein serine/threonine kinase activity, protein binding, protein kinase activity, protein serine/threonine kinase activity Human CDK15 IntAct UniProtKB {GO:0005515=PMID:22939624, GO:0004674=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0004693=GO_REF:0000003} Q96Q40 Cyclin-dependent kinase 15 protein 20130415 {GO:0005515=IPI, GO:0004674=IEA, GO:0005524=IEA, GO:0046872=IEA, GO:0004693=IEA} ATP binding, cyclin-dependent protein serine/threonine kinase activity, metal ion binding, protein binding, protein serine/threonine kinase activity Human UniProtKB:P08238 CDK16 IntAct UniProtKB {GO:0005515=PMID:16091426, GO:0030133=GO_REF:0000039, GO:0043005=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0007283=GO_REF:0000024, GO:0006887=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0031175=GO_REF:0000024, GO:0031234=PMID:22184064, GO:0008021=GO_REF:0000024, GO:0005737=PMID:22798068, GO:0004674=PMID:22184064, GO:0006468=PMID:1437147, GO:0030252=GO_REF:0000024, GO:0061178=PMID:22798068, GO:0016772=GO_REF:0000002, GO:0004693=GO_REF:0000003} Q00536 Cyclin-dependent kinase 16 protein 20130415 {GO:0005515=IPI, GO:0030133=IEA, GO:0043005=IEA, GO:0030054=IEA, GO:0007283=ISS, GO:0006887=ISS, GO:0005524=IEA, GO:0031175=ISS, GO:0031234=IDA, GO:0008021=ISS, GO:0005737=IDA, GO:0004674=IDA, GO:0006468=TAS, GO:0030252=ISS, GO:0061178=IMP, GO:0016772=IEA, GO:0004693=IEA} exocytosis, growth hormone secretion, neuron projection development, protein phosphorylation, regulation of insulin secretion involved in cellular response to glucose stimulus, spermatogenesis cell junction, cytoplasm, extrinsic to internal side of plasma membrane, neuron projection, synaptic vesicle, transport vesicle ATP binding, cyclin-dependent protein serine/threonine kinase activity, protein binding, protein serine/threonine kinase activity, transferase activity, transferring phosphorus-containing groups Human UniProtKB:Q15436 CDK17 PINC UniProtKB {GO:0004672=PMID:1639063, GO:0004674=GO_REF:0000002, GO:0006468=PMID:1639063, GO:0005524=GO_REF:0000037, GO:0004693=GO_REF:0000003} Q00537 Cyclin-dependent kinase 17 protein 20030904 {GO:0004672=TAS, GO:0004674=IEA, GO:0006468=TAS, GO:0005524=IEA, GO:0004693=IEA} protein phosphorylation ATP binding, cyclin-dependent protein serine/threonine kinase activity, protein kinase activity, protein serine/threonine kinase activity Human CDK18 UniProtKB UniProtKB {GO:0007165=GO_REF:0000029, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000029, GO:0006468=GO_REF:0000029, GO:0005575=GO_REF:0000015, GO:0004871=GO_REF:0000029, GO:0005524=GO_REF:0000029, GO:0004693=GO_REF:0000003} Q07002 Cyclin-dependent kinase 18 protein 20061026 {GO:0007165=NAS, GO:0004672=IEA, GO:0004674=NAS, GO:0006468=NAS, GO:0005575=ND, GO:0004871=NAS, GO:0005524=NAS, GO:0004693=IEA} protein phosphorylation, signal transduction cellular_component ATP binding, cyclin-dependent protein serine/threonine kinase activity, protein kinase activity, protein serine/threonine kinase activity, signal transducer activity Human CDK19 UniProtKB UniProtKB {GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0004693=GO_REF:0000003, GO:0051301=GO_REF:0000038} Q9BWU1 Cyclin-dependent kinase 19 protein 20130413 {GO:0004672=IEA, GO:0004674=IEA, GO:0005524=IEA, GO:0004693=IEA, GO:0051301=IEA} cell division ATP binding, cyclin-dependent protein serine/threonine kinase activity, protein kinase activity, protein serine/threonine kinase activity Human EC:2.7.11.22 CDK2 GOC UniProtKB {GO:0005515=PMID:23455922, GO:0032298=GO_REF:0000019, GO:0000793=GO_REF:0000019, GO:0008284=PMID:10767298, GO:0015030=PMID:10995387, GO:0071732=PMID:20079829, GO:0007265=PMID:9054499, GO:0005634=PMID:10767298, GO:0031145=Reactome:REACT_6828, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_9065, GO:0000084=Reactome:REACT_899, GO:0000085=Reactome:REACT_1915, GO:0000082=Reactome:REACT_1783, GO:0005737=PMID:10767298, GO:0000086=PMID:1653904, GO:0006813=GO_REF:0000019, GO:0006977=Reactome:REACT_1625, GO:0005667=GO_REF:0000019, GO:0000806=GO_REF:0000019, GO:0005813=PMID:19238148, GO:0000781=GO_REF:0000019, GO:0030332=PMID:1653904, GO:0000805=GO_REF:0000019, GO:0016572=PMID:8692841, GO:0005524=GO_REF:0000037, GO:0051439=Reactome:REACT_6837, GO:0006260=Reactome:REACT_6769, GO:0051298=PMID:19238148, GO:0007067=GO_REF:0000037, GO:0035173=PMID:8692841, GO:0006281=GO_REF:0000037, GO:0007126=PMID:19238148, GO:0060968=PMID:20935635, GO:0007596=Reactome:REACT_604, GO:0004674=GO_REF:0000002, GO:0000307=PMID:8692841, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_111202, GO:0031571=PMID:21319273, GO:0000278=Reactome:REACT_152, GO:0045893=GO_REF:0000019, GO:0005768=PMID:21262353, GO:0004693=Reactome:REACT_9023, GO:0051301=GO_REF:0000037} P24941 Cyclin-dependent kinase 2 protein 20130413 {GO:0005515=IPI, GO:0032298=IEA, GO:0000793=IEA, GO:0008284=IDA, GO:0015030=IDA, GO:0071732=TAS, GO:0007265=IEP, GO:0005634=IDA, GO:0031145=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0000084=TAS, GO:0000085=TAS, GO:0000082=TAS, GO:0005737=IDA, GO:0000086=NAS, GO:0006813=IEA, GO:0006977=TAS, GO:0005667=IEA, GO:0000806=IEA, GO:0005813=TAS, GO:0000781=IEA, GO:0030332=IDA, GO:0000805=IEA, GO:0016572=IDA, GO:0005524=IEA, GO:0051439=TAS, GO:0006260=TAS, GO:0051298=TAS, GO:0007067=IEA, GO:0035173=IDA, GO:0006281=IEA, GO:0007126=TAS, GO:0060968=IDA, GO:0007596=TAS, GO:0004674=IEA, GO:0000307=IDA, GO:0000075=TAS, GO:0005654=TAS, GO:0031571=TAS, GO:0000278=TAS, GO:0045893=IEA, GO:0005768=IDA, GO:0004693=TAS, GO:0051301=IEA} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, DNA repair, DNA replication, G1/S transition of mitotic cell cycle, G2 phase of mitotic cell cycle, G2/M transition of mitotic cell cycle, Ras protein signal transduction, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, blood coagulation, cell cycle checkpoint, cell division, cellular response to nitric oxide, centrosome duplication, histone phosphorylation, meiosis, mitosis, mitotic G1 DNA damage checkpoint, mitotic cell cycle, positive regulation of DNA-dependent DNA replication initiation, positive regulation of cell proliferation, positive regulation of transcription, DNA-dependent, potassium ion transport, regulation of gene silencing, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle Cajal body, X chromosome, Y chromosome, centrosome, chromosome, telomeric region, condensed chromosome, cyclin-dependent protein kinase holoenzyme complex, cytoplasm, cytosol, endosome, nucleoplasm, nucleus, transcription factor complex ATP binding, cyclin binding, cyclin-dependent protein serine/threonine kinase activity, histone kinase activity, metal ion binding, protein binding, protein serine/threonine kinase activity Human CDK20 UniProtKB UniProtKB {GO:0005515=PMID:21986944, GO:0005929=GO_REF:0000039, GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0004693=GO_REF:0000003, GO:0051301=GO_REF:0000037} Q8IZL9 Cyclin-dependent kinase 20 protein 20120708 {GO:0005515=IPI, GO:0005929=IEA, GO:0005737=IEA, GO:0005634=IEA, GO:0007275=IEA, GO:0005524=IEA, GO:0004693=IEA, GO:0051301=IEA} cell division, multicellular organismal development cilium, cytoplasm, nucleus ATP binding, cyclin-dependent protein serine/threonine kinase activity, protein binding Human UniProtKB:P20794 CDK2AP1 PINC UniProtKB {GO:0000084=PMID:9506968, GO:0006261=PMID:9506968, GO:0005737=PMID:9506968, GO:0006468=PMID:9506968, GO:0005634=PMID:9506968, GO:0003677=PMID:9506968} O14519 Cyclin-dependent kinase 2-associated protein 1 protein 20030904 {GO:0000084=TAS, GO:0006261=TAS, GO:0005737=TAS, GO:0006468=TAS, GO:0005634=TAS, GO:0003677=TAS} DNA-dependent DNA replication, S phase of mitotic cell cycle, protein phosphorylation cytoplasm, nucleus DNA binding Human CDK2AP2 null null {} null null null null {} null null null CDK3 UniProtKB UniProtKB {GO:0000082=PMID:8846921, GO:0007067=GO_REF:0000037, GO:0008283=PMID:18794154, GO:0004674=GO_REF:0000038, GO:0005524=GO_REF:0000037, GO:0045023=PMID:15084261, GO:0004693=GO_REF:0000003, GO:0051301=GO_REF:0000037} Q00526 Cyclin-dependent kinase 3 protein 20110912 {GO:0000082=TAS, GO:0007067=IEA, GO:0008283=TAS, GO:0004674=IEA, GO:0005524=IEA, GO:0045023=TAS, GO:0004693=IEA, GO:0051301=IEA} G0 to G1 transition, G1/S transition of mitotic cell cycle, cell division, cell proliferation, mitosis ATP binding, cyclin-dependent protein serine/threonine kinase activity, protein serine/threonine kinase activity Human CDK4 UniProtKB UniProtKB {GO:0010468=PMID:17420273, GO:0005515=PMID:8741839, GO:0008284=PMID:7603984, GO:0048471=GO_REF:0000019, GO:0031100=GO_REF:0000019, GO:0005634=PMID:16109376, GO:0048146=PMID:17420273, GO:0032403=GO_REF:0000019, GO:0005829=Reactome:REACT_7947, GO:0000084=Reactome:REACT_899, GO:0000082=PMID:7603984, GO:0051726=GO_REF:0000019, GO:0000080=Reactome:REACT_1590, GO:0000785=PMID:18827403, GO:0010288=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0031965=PMID:18827403, GO:0043065=GO_REF:0000019, GO:0030332=GO_REF:0000019, GO:0042493=PMID:18291362, GO:0005730=PMID:18827403, GO:0009636=GO_REF:0000019, GO:0045727=GO_REF:0000019, GO:0033574=GO_REF:0000019, GO:0005524=GO_REF:0000038, GO:0007165=GO_REF:0000019, GO:0045793=GO_REF:0000019, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000038, GO:0000307=PMID:17420273, GO:0055093=GO_REF:0000019, GO:0007623=GO_REF:0000019, GO:0006468=PMID:8114739, GO:0005654=Reactome:REACT_111248, GO:0005923=GO_REF:0000019, GO:0000278=Reactome:REACT_152, GO:0004693=PMID:8114739, GO:0051301=GO_REF:0000037} Q96BE9 Cyclin-dependent kinase 4 protein 20130413 {GO:0010468=IMP, GO:0005515=IPI, GO:0008284=IMP, GO:0048471=IEA, GO:0031100=IEA, GO:0005634=IDA, GO:0048146=IMP, GO:0032403=IEA, GO:0005829=TAS, GO:0000084=TAS, GO:0000082=IMP, GO:0051726=IEA, GO:0000080=TAS, GO:0000785=IDA, GO:0010288=IEA, GO:0005667=IEA, GO:0031965=IDA, GO:0043065=IEA, GO:0030332=IEA, GO:0042493=IGI, GO:0005730=IDA, GO:0009636=IEA, GO:0045727=IEA, GO:0033574=IEA, GO:0005524=IEA, GO:0007165=IEA, GO:0045793=IEA, GO:0004672=IEA, GO:0004674=IEA, GO:0000307=IDA, GO:0055093=IEA, GO:0007623=IEA, GO:0006468=IDA, GO:0005654=TAS, GO:0005923=IEA, GO:0000278=TAS, GO:0004693=IDA, GO:0051301=IEA} G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, cell division, circadian rhythm, mitotic cell cycle, organ regeneration, positive regulation of apoptotic process, positive regulation of cell proliferation, positive regulation of cell size, positive regulation of fibroblast proliferation, positive regulation of translation, protein phosphorylation, regulation of cell cycle, regulation of gene expression, response to drug, response to hyperoxia, response to lead ion, response to testosterone stimulus, response to toxic substance, signal transduction chromatin, cyclin-dependent protein kinase holoenzyme complex, cytosol, nuclear membrane, nucleolus, nucleoplasm, nucleus, perinuclear region of cytoplasm, tight junction, transcription factor complex ATP binding, cyclin binding, cyclin-dependent protein serine/threonine kinase activity, protein binding, protein complex binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB-KW:KW-0067 CDK5 IntAct UniProtKB {GO:0071156=PMID:21473899, GO:0005515=PMID:23455922, GO:0031594=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0048709=PMID:18042622, GO:0021697=GO_REF:0000019, GO:0050321=GO_REF:0000024, GO:2000251=PMID:21473899, GO:0009790=GO_REF:0000024, GO:0051402=PMID:21473899, GO:0006886=GO_REF:0000019, GO:0031175=GO_REF:0000024, GO:0043525=GO_REF:0000024, GO:0046777=GO_REF:0000019, GO:0018105=PMID:21145489, GO:0007411=Reactome:REACT_18266, GO:0048167=GO_REF:0000024, GO:0016301=GO_REF:0000024, GO:0045211=GO_REF:0000037, GO:0018107=GO_REF:0000019, GO:0045860=GO_REF:0000019, GO:0043025=GO_REF:0000024, GO:0031397=GO_REF:0000019, GO:0061001=GO_REF:0000024, GO:0043125=GO_REF:0000024, GO:0030334=GO_REF:0000019, GO:0060079=GO_REF:0000019, GO:0014069=GO_REF:0000024, GO:0090314=GO_REF:0000019, GO:0048488=PMID:21473899, GO:0045786=GO_REF:0000019, GO:0016079=PMID:21473899, GO:0007416=PMID:21473899, GO:0030027=GO_REF:0000039, GO:0005176=GO_REF:0000024, GO:0016310=PMID:20357208, GO:0070509=GO_REF:0000019, GO:0008045=GO_REF:0000019, GO:0030549=GO_REF:0000024, GO:0046875=GO_REF:0000019, GO:0007519=GO_REF:0000019, GO:0008542=GO_REF:0000019, GO:0045892=PMID:20357208, GO:0004693=GO_REF:0000024, GO:0051301=GO_REF:0000037, GO:0030424=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0008283=PMID:8090221, GO:0048148=GO_REF:0000019, GO:0007268=PMID:21473899, GO:0035418=GO_REF:0000019, GO:0048675=PMID:21473899, GO:0005634=GO_REF:0000024, GO:0030175=GO_REF:0000019, GO:0030425=GO_REF:0000024, GO:0005829=Reactome:REACT_19321, GO:0030426=GO_REF:0000024, GO:0032092=GO_REF:0000019, GO:0046826=GO_REF:0000019, GO:0002039=GO_REF:0000019, GO:0045055=GO_REF:0000019, GO:0005737=GO_REF:0000024, GO:0031914=GO_REF:0000019, GO:0033136=GO_REF:0000019, GO:0030182=PMID:21473899, GO:0001963=GO_REF:0000019, GO:0043204=GO_REF:0000039, GO:0021954=GO_REF:0000019, GO:0014044=GO_REF:0000019, GO:0035249=GO_REF:0000019, GO:0016533=GO_REF:0000019, GO:0042981=PMID:21473899, GO:0021819=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0019233=GO_REF:0000019, GO:0006913=GO_REF:0000019, GO:0048813=GO_REF:0000019, GO:0021766=GO_REF:0000019, GO:0022038=GO_REF:0000019, GO:0004672=PMID:1639063, GO:0016020=GO_REF:0000024, GO:0007160=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0030866=GO_REF:0000019, GO:0045956=GO_REF:0000019, GO:0004674=Reactome:REACT_19285, GO:0032801=GO_REF:0000019, GO:0043113=GO_REF:0000019, GO:0001764=PMID:21473899} Q00535 Cyclin-dependent kinase 5 protein 20130415 {GO:0071156=TAS, GO:0005515=IPI, GO:0031594=ISS, GO:0030054=IEA, GO:0048709=IDA, GO:0021697=IEA, GO:0050321=ISS, GO:2000251=TAS, GO:0009790=ISS, GO:0051402=TAS, GO:0006886=IEA, GO:0031175=ISS, GO:0043525=ISS, GO:0046777=IEA, GO:0018105=IDA, GO:0007411=TAS, GO:0048167=ISS, GO:0016301=ISS, GO:0045211=IEA, GO:0018107=IEA, GO:0045860=IEA, GO:0043025=ISS, GO:0031397=IEA, GO:0061001=ISS, GO:0043125=ISS, GO:0030334=IEA, GO:0060079=IEA, GO:0014069=ISS, GO:0090314=IEA, GO:0048488=TAS, GO:0045786=IEA, GO:0016079=TAS, GO:0007416=TAS, GO:0030027=IEA, GO:0005176=ISS, GO:0016310=IDA, GO:0070509=IEA, GO:0008045=IEA, GO:0030549=ISS, GO:0046875=IEA, GO:0007519=IEA, GO:0008542=IEA, GO:0045892=IMP, GO:0004693=ISS, GO:0051301=IEA, GO:0030424=ISS, GO:0005886=IEA, GO:0008283=TAS, GO:0048148=IEA, GO:0007268=TAS, GO:0035418=IEA, GO:0048675=TAS, GO:0005634=ISS, GO:0030175=IEA, GO:0030425=ISS, GO:0005829=TAS, GO:0030426=ISS, GO:0032092=IEA, GO:0046826=IEA, GO:0002039=IEA, GO:0045055=IEA, GO:0005737=ISS, GO:0031914=IEA, GO:0033136=IEA, GO:0030182=TAS, GO:0001963=IEA, GO:0043204=IEA, GO:0021954=IEA, GO:0014044=IEA, GO:0035249=IEA, GO:0016533=IEA, GO:0042981=TAS, GO:0021819=IEA, GO:0005524=IEA, GO:0019233=IEA, GO:0006913=IEA, GO:0048813=IEA, GO:0021766=IEA, GO:0022038=IEA, GO:0004672=TAS, GO:0016020=ISS, GO:0007160=IEA, GO:0007596=TAS, GO:0030866=IEA, GO:0045956=IEA, GO:0004674=TAS, GO:0032801=IEA, GO:0043113=IEA, GO:0001764=TAS} Schwann cell development, axon extension, axon guidance, behavioral response to cocaine, blood coagulation, calcium ion import, cell division, cell proliferation, cell-matrix adhesion, central nervous system neuron development, cerebellar cortex formation, corpus callosum development, cortical actin cytoskeleton organization, dendrite morphogenesis, embryo development, hippocampus development, intracellular protein transport, layer formation in cerebral cortex, motor neuron axon guidance, negative regulation of cell cycle, negative regulation of protein export from nucleus, negative regulation of protein ubiquitination, negative regulation of synaptic plasticity, negative regulation of transcription, DNA-dependent, neuron apoptotic process, neuron differentiation, neuron migration, neuron projection development, nucleocytoplasmic transport, oligodendrocyte differentiation, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, phosphorylation, positive regulation of actin cytoskeleton reorganization, positive regulation of calcium ion-dependent exocytosis, positive regulation of neuron apoptotic process, positive regulation of protein binding, positive regulation of protein kinase activity, positive regulation of protein targeting to membrane, protein autophosphorylation, protein localization to synapse, receptor catabolic process, receptor clustering, regulated secretory pathway, regulation of apoptotic process, regulation of cell cycle arrest, regulation of cell migration, regulation of dendritic spine morphogenesis, regulation of excitatory postsynaptic membrane potential, regulation of synaptic plasticity, sensory perception of pain, serine phosphorylation of STAT3 protein, skeletal muscle tissue development, synapse assembly, synaptic transmission, synaptic transmission, dopaminergic, synaptic transmission, glutamatergic, synaptic vesicle endocytosis, synaptic vesicle exocytosis, visual learning axon, cell junction, cyclin-dependent protein kinase 5 holoenzyme complex, cytoplasm, cytosol, dendrite, filopodium, growth cone, lamellipodium, membrane, neuromuscular junction, neuronal cell body, nucleus, perikaryon, plasma membrane, postsynaptic density, postsynaptic membrane ATP binding, ErbB-2 class receptor binding, ErbB-3 class receptor binding, acetylcholine receptor activator activity, cyclin-dependent protein serine/threonine kinase activity, ephrin receptor binding, kinase activity, p53 binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, tau-protein kinase activity Human UniProtKB:P46527 CDK5R1 IntAct UniProtKB {GO:0005515=PMID:15689152, GO:0031594=GO_REF:0000024, GO:0009790=GO_REF:0000024, GO:0031175=GO_REF:0000024, GO:0043525=GO_REF:0000024, GO:0007413=GO_REF:0000024, GO:0018105=PMID:12832520, GO:0016301=GO_REF:0000024, GO:0007411=Reactome:REACT_18266, GO:0021722=GO_REF:0000019, GO:0032956=GO_REF:0000019, GO:0018107=PMID:12832520, GO:0043025=GO_REF:0000024, GO:0061001=GO_REF:0000024, GO:0045296=GO_REF:0000024, GO:0019901=PMID:12832520, GO:0005509=GO_REF:0000024, GO:0090314=GO_REF:0000019, GO:0014069=GO_REF:0000024, GO:0021549=GO_REF:0000019, GO:0007213=GO_REF:0000024, GO:0070507=GO_REF:0000019, GO:0035235=GO_REF:0000024, GO:0046875=GO_REF:0000019, GO:0007420=PMID:10915792, GO:0043539=PMID:12832520, GO:0045892=PMID:20357208, GO:0004693=GO_REF:0000019, GO:0030424=GO_REF:0000024, GO:0048471=PMID:12832520, GO:0005886=GO_REF:0000039, GO:0008283=PMID:8090221, GO:0005634=GO_REF:0000024, GO:0000079=PMID:7592934, GO:0030425=GO_REF:0000024, GO:0005829=Reactome:REACT_19321, GO:0030426=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0043197=GO_REF:0000024, GO:0033136=GO_REF:0000019, GO:0043292=GO_REF:0000024, GO:0030182=GO_REF:0000024, GO:0007158=GO_REF:0000024, GO:0048013=GO_REF:0000024, GO:0016534=GO_REF:0000019, GO:0016533=GO_REF:0000002, GO:0021819=GO_REF:0000019, GO:0021766=GO_REF:0000019, GO:0004672=PMID:7592934, GO:0016020=GO_REF:0000024, GO:0045664=PMID:10721722, GO:0001764=GO_REF:0000024} Q15078 Cyclin-dependent kinase 5 activator 1 protein 20130415 {GO:0005515=IPI, GO:0031594=ISS, GO:0009790=ISS, GO:0031175=ISS, GO:0043525=ISS, GO:0007413=ISS, GO:0018105=IDA, GO:0016301=ISS, GO:0007411=TAS, GO:0021722=IEA, GO:0032956=IEA, GO:0018107=IDA, GO:0043025=ISS, GO:0061001=ISS, GO:0045296=ISS, GO:0019901=IPI, GO:0005509=ISS, GO:0090314=IEA, GO:0014069=ISS, GO:0021549=IEA, GO:0007213=ISS, GO:0070507=IEA, GO:0035235=ISS, GO:0046875=IEA, GO:0007420=NAS, GO:0043539=IDA, GO:0045892=IMP, GO:0004693=IEA, GO:0030424=ISS, GO:0048471=IDA, GO:0005886=IEA, GO:0008283=TAS, GO:0005634=ISS, GO:0000079=TAS, GO:0030425=ISS, GO:0005829=TAS, GO:0030426=ISS, GO:0005737=ISS, GO:0043197=ISS, GO:0033136=IEA, GO:0043292=ISS, GO:0030182=ISS, GO:0007158=ISS, GO:0048013=ISS, GO:0016534=IEA, GO:0016533=IEA, GO:0021819=IEA, GO:0021766=IEA, GO:0004672=TAS, GO:0016020=ISS, GO:0045664=NAS, GO:0001764=ISS} G-protein coupled acetylcholine receptor signaling pathway, axon guidance, axonal fasciculation, brain development, cell proliferation, cerebellum development, embryo development, ephrin receptor signaling pathway, hippocampus development, ionotropic glutamate receptor signaling pathway, layer formation in cerebral cortex, negative regulation of transcription, DNA-dependent, neuron cell-cell adhesion, neuron differentiation, neuron migration, neuron projection development, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, positive regulation of neuron apoptotic process, positive regulation of protein targeting to membrane, regulation of actin cytoskeleton organization, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of dendritic spine morphogenesis, regulation of microtubule cytoskeleton organization, regulation of neuron differentiation, serine phosphorylation of STAT3 protein, superior olivary nucleus maturation axon, contractile fiber, cyclin-dependent protein kinase 5 holoenzyme complex, cytoplasm, cytosol, dendrite, dendritic spine, growth cone, membrane, neuromuscular junction, neuronal cell body, nucleus, perinuclear region of cytoplasm, plasma membrane, postsynaptic density cadherin binding, calcium ion binding, cyclin-dependent protein kinase 5 activator activity, cyclin-dependent protein serine/threonine kinase activity, ephrin receptor binding, kinase activity, protein binding, protein kinase activity, protein kinase binding, protein serine/threonine kinase activator activity Human UniProtKB:Q00535 CDK5R2 PINC UniProtKB {GO:0021766=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0045956=GO_REF:0000019, GO:0021722=GO_REF:0000019, GO:0016534=GO_REF:0000019, GO:0016533=GO_REF:0000002, GO:0021549=GO_REF:0000019, GO:0000079=PMID:7592934, GO:0021819=GO_REF:0000019, GO:0001764=GO_REF:0000019, GO:0008289=GO_REF:0000037} Q13319 Cyclin-dependent kinase 5 activator 2 protein 20030904 {GO:0021766=IEA, GO:0005737=IEA, GO:0005886=IEA, GO:0045956=IEA, GO:0021722=IEA, GO:0016534=IEA, GO:0016533=IEA, GO:0021549=IEA, GO:0000079=TAS, GO:0021819=IEA, GO:0001764=IEA, GO:0008289=IEA} cerebellum development, hippocampus development, layer formation in cerebral cortex, neuron migration, positive regulation of calcium ion-dependent exocytosis, regulation of cyclin-dependent protein serine/threonine kinase activity, superior olivary nucleus maturation cyclin-dependent protein kinase 5 holoenzyme complex, cytoplasm, plasma membrane cyclin-dependent protein kinase 5 activator activity, lipid binding Human CDK5RAP1 UniProtKB UniProtKB {GO:0051539=GO_REF:0000037, GO:0019901=PMID:10721722, GO:0045736=PMID:11882646, GO:0005575=GO_REF:0000015, GO:0003824=GO_REF:0000002, GO:0032403=GO_REF:0000019, GO:0006400=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0005737=GO_REF:0000002, GO:0007420=PMID:10915792, GO:0045664=PMID:10721722, GO:0009451=GO_REF:0000002, GO:0016740=GO_REF:0000002} Q96SZ6 CDK5 regulatory subunit-associated protein 1 protein 20061026 {GO:0051539=IEA, GO:0019901=NAS, GO:0045736=IDA, GO:0005575=ND, GO:0003824=IEA, GO:0032403=IEA, GO:0006400=IEA, GO:0046872=IEA, GO:0005737=IEA, GO:0007420=NAS, GO:0045664=NAS, GO:0009451=IEA, GO:0016740=IEA} RNA modification, brain development, negative regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of neuron differentiation, tRNA modification cellular_component, cytoplasm 4 iron, 4 sulfur cluster binding, catalytic activity, metal ion binding, protein complex binding, protein kinase binding, transferase activity Human CDK5RAP2 HPA UniProtKB {GO:0008017=PMID:14654843, GO:0005515=PMID:19282672, GO:0005516=PMID:20466722, GO:0048471=PMID:17959831, GO:0030054=GO_REF:0000052, GO:0044212=PMID:19282672, GO:0001578=PMID:19553473, GO:0000132=GO_REF:0000024, GO:0032403=GO_REF:0000019, GO:0005829=Reactome:REACT_15470, GO:0005737=PMID:19282672, GO:0007059=PMID:19282672, GO:0015631=PMID:17959831, GO:0000086=Reactome:REACT_2203, GO:0005856=PMID:10721722, GO:0000242=PMID:17959831, GO:0022008=GO_REF:0000024, GO:0090231=PMID:19282672, GO:0005813=GO_REF:0000052, GO:0005794=PMID:20466722, GO:0019901=PMID:10721722, GO:0005874=PMID:19553473, GO:0000226=PMID:17959831, GO:0046600=GO_REF:0000024, GO:0051297=PMID:18042621, GO:0000922=PMID:19282672, GO:0045665=GO_REF:0000019, GO:0007420=GO_REF:0000024, GO:0045664=PMID:10721722, GO:0000278=Reactome:REACT_152, GO:0045893=PMID:19282672} Q96SN8 CDK5 regulatory subunit-associated protein 2 protein 20111111 {GO:0008017=IDA, GO:0005515=IPI, GO:0005516=IPI, GO:0048471=IDA, GO:0030054=IDA, GO:0044212=IDA, GO:0001578=IDA, GO:0000132=ISS, GO:0032403=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0007059=IMP, GO:0015631=IPI, GO:0000086=TAS, GO:0005856=NAS, GO:0000242=IDA, GO:0022008=ISS, GO:0090231=IDA, GO:0005813=IDA, GO:0005794=IDA, GO:0019901=IPI, GO:0005874=IDA, GO:0000226=IDA, GO:0046600=ISS, GO:0051297=IMP, GO:0000922=IDA, GO:0045665=IEA, GO:0007420=ISS, GO:0045664=NAS, GO:0000278=TAS, GO:0045893=IDA} G2/M transition of mitotic cell cycle, brain development, centrosome organization, chromosome segregation, establishment of mitotic spindle orientation, microtubule bundle formation, microtubule cytoskeleton organization, mitotic cell cycle, negative regulation of centriole replication, negative regulation of neuron differentiation, neurogenesis, positive regulation of transcription, DNA-dependent, regulation of neuron differentiation, regulation of spindle checkpoint Golgi apparatus, cell junction, centrosome, cytoplasm, cytoskeleton, cytosol, microtubule, pericentriolar material, perinuclear region of cytoplasm, spindle pole calmodulin binding, microtubule binding, protein binding, protein complex binding, protein kinase binding, transcription regulatory region DNA binding, tubulin binding Human CDK5RAP3 IntAct UniProtKB {GO:0005515=PMID:17785205, GO:0019901=PMID:10721722, GO:0007420=PMID:10915792, GO:0045944=GO_REF:0000019, GO:0045664=PMID:10721722, GO:0000079=GO_REF:0000024, GO:0005575=GO_REF:0000015} Q96JB5 CDK5 regulatory subunit-associated protein 3 protein 20130415 {GO:0005515=IPI, GO:0019901=NAS, GO:0007420=NAS, GO:0045944=IEA, GO:0045664=NAS, GO:0000079=ISS, GO:0005575=ND} brain development, positive regulation of transcription from RNA polymerase II promoter, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of neuron differentiation cellular_component protein binding, protein kinase binding Human UniProtKB:Q04206 CDK6 BHF-UCL UniProtKB {GO:0005515=PMID:8001816, GO:0010468=PMID:15254224, GO:0008285=PMID:16294322, GO:0050680=PMID:14985467, GO:0048699=PMID:21319271, GO:2000145=PMID:16767702, GO:0005634=PMID:14985467, GO:0048146=PMID:17420273, GO:0005829=Reactome:REACT_7947, GO:0005737=PMID:14985467, GO:0000082=PMID:16294322, GO:0007219=GO_REF:0000019, GO:0002244=GO_REF:0000019, GO:0045638=PMID:17431401, GO:0043697=PMID:12861051, GO:0007050=PMID:16294322, GO:0000080=PMID:8114739, GO:2000773=PMID:17420273, GO:0021542=PMID:21319271, GO:0033077=GO_REF:0000019, GO:0030332=PMID:8114739, GO:0003323=PMID:20668294, GO:0009615=PMID:16548883, GO:0045786=PMID:14985467, GO:0060218=GO_REF:0000019, GO:0001726=PMID:10205165, GO:0005524=PMID:9751050, GO:0042063=PMID:12861051, GO:0010628=GO_REF:0000019, GO:0045668=PMID:15254224, GO:0021670=PMID:21319271, GO:0014002=PMID:16767702, GO:0000307=PMID:17420273, GO:0045646=PMID:12833137, GO:0006468=PMID:8114739, GO:0045596=PMID:16294322, GO:0000278=Reactome:REACT_152, GO:0001954=PMID:10205165, GO:0051301=GO_REF:0000037, GO:0004693=PMID:8114739} Q00534 Cyclin-dependent kinase 6 protein 20071120 {GO:0005515=IPI, GO:0010468=IDA, GO:0008285=TAS, GO:0050680=IMP, GO:0048699=ISS, GO:2000145=ISS, GO:0005634=IDA, GO:0048146=IMP, GO:0005829=TAS, GO:0005737=IDA, GO:0000082=TAS, GO:0007219=IEA, GO:0002244=IEA, GO:0045638=IDA, GO:0043697=IMP, GO:0007050=TAS, GO:0000080=IEP, GO:2000773=IDA, GO:0021542=ISS, GO:0033077=IEA, GO:0030332=IPI, GO:0003323=IDA, GO:0009615=IEP, GO:0045786=IDA, GO:0060218=IEA, GO:0001726=IDA, GO:0005524=IDA, GO:0042063=IMP, GO:0010628=IEA, GO:0045668=IDA, GO:0021670=ISS, GO:0014002=ISS, GO:0000307=IDA, GO:0045646=IMP, GO:0006468=IDA, GO:0045596=TAS, GO:0000278=TAS, GO:0001954=IDA, GO:0051301=IEA, GO:0004693=IDA} G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, Notch signaling pathway, T cell differentiation in thymus, astrocyte development, cell cycle arrest, cell dedifferentiation, cell division, dentate gyrus development, generation of neurons, gliogenesis, hematopoietic progenitor cell differentiation, hematopoietic stem cell differentiation, lateral ventricle development, mitotic cell cycle, negative regulation of cell cycle, negative regulation of cell differentiation, negative regulation of cell proliferation, negative regulation of cellular senescence, negative regulation of epithelial cell proliferation, negative regulation of myeloid cell differentiation, negative regulation of osteoblast differentiation, positive regulation of cell-matrix adhesion, positive regulation of fibroblast proliferation, positive regulation of gene expression, protein phosphorylation, regulation of cell motility, regulation of erythrocyte differentiation, regulation of gene expression, response to virus, type B pancreatic cell development cyclin-dependent protein kinase holoenzyme complex, cytoplasm, cytosol, nucleus, ruffle ATP binding, cyclin binding, cyclin-dependent protein serine/threonine kinase activity, protein binding Human UniProtKB:P42773 CDK7 HPA UniProtKB {GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006368=Reactome:REACT_2089, GO:0048471=GO_REF:0000039, GO:0006367=Reactome:REACT_1851, GO:0006366=Reactome:REACT_1366, GO:0008283=PMID:7533895, GO:0006363=Reactome:REACT_1074, GO:0006362=Reactome:REACT_2204, GO:0006361=Reactome:REACT_1974, GO:0006360=Reactome:REACT_1309, GO:0005634=GO_REF:0000052, GO:0050681=PMID:15572661, GO:0000079=PMID:7533895, GO:0005739=GO_REF:0000052, GO:0000084=Reactome:REACT_899, GO:0005737=GO_REF:0000052, GO:0000082=Reactome:REACT_1783, GO:0000086=Reactome:REACT_2203, GO:0045944=PMID:8692841, GO:0016032=Reactome:REACT_6256, GO:0007050=PMID:15876871, GO:0000080=Reactome:REACT_1590, GO:0008094=PMID:9852112, GO:0003713=PMID:15572661, GO:0006370=Reactome:REACT_1470, GO:0008022=PMID:10801852, GO:0005524=GO_REF:0000037, GO:0008353=PMID:9852112, GO:0050434=Reactome:REACT_6162, GO:0006281=Reactome:REACT_216, GO:0004672=PMID:9852112, GO:0006283=Reactome:REACT_1628, GO:0004674=GO_REF:0000002, GO:0005654=Reactome:REACT_9070, GO:0006289=Reactome:REACT_1826, GO:0000278=Reactome:REACT_152, GO:0045893=PMID:15572661, GO:0000718=Reactome:REACT_311, GO:0005675=PMID:9852112, GO:0030521=PMID:15572661, GO:0004693=GO_REF:0000003, GO:0051301=GO_REF:0000037} P50613 Cyclin-dependent kinase 7 protein 20101115 {GO:0022415=TAS, GO:0010467=TAS, GO:0006368=TAS, GO:0048471=IEA, GO:0006367=TAS, GO:0006366=TAS, GO:0008283=TAS, GO:0006363=TAS, GO:0006362=TAS, GO:0006361=TAS, GO:0006360=TAS, GO:0005634=IDA, GO:0050681=NAS, GO:0000079=TAS, GO:0005739=IDA, GO:0000084=TAS, GO:0005737=IDA, GO:0000082=TAS, GO:0000086=TAS, GO:0045944=IDA, GO:0016032=TAS, GO:0007050=TAS, GO:0000080=TAS, GO:0008094=IDA, GO:0003713=NAS, GO:0006370=TAS, GO:0008022=IPI, GO:0005524=IEA, GO:0008353=IDA, GO:0050434=TAS, GO:0006281=TAS, GO:0004672=IDA, GO:0006283=TAS, GO:0004674=IEA, GO:0005654=TAS, GO:0006289=TAS, GO:0000278=TAS, GO:0045893=NAS, GO:0000718=TAS, GO:0005675=IDA, GO:0030521=NAS, GO:0004693=IEA, GO:0051301=IEA} 7-methylguanosine mRNA capping, DNA repair, G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, G2/M transition of mitotic cell cycle, S phase of mitotic cell cycle, androgen receptor signaling pathway, cell cycle arrest, cell division, cell proliferation, gene expression, mitotic cell cycle, nucleotide-excision repair, nucleotide-excision repair, DNA damage removal, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of viral transcription, regulation of cyclin-dependent protein serine/threonine kinase activity, termination of RNA polymerase I transcription, transcription elongation from RNA polymerase I promoter, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase I promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase I promoter, transcription initiation from RNA polymerase II promoter, transcription-coupled nucleotide-excision repair, viral reproduction, viral reproductive process cytoplasm, holo TFIIH complex, mitochondrion, nucleoplasm, nucleus, perinuclear region of cytoplasm ATP binding, DNA-dependent ATPase activity, RNA polymerase II carboxy-terminal domain kinase activity, androgen receptor binding, cyclin-dependent protein serine/threonine kinase activity, protein C-terminus binding, protein kinase activity, protein serine/threonine kinase activity, transcription coactivator activity Human CDK8 IntAct UniProtKB {GO:0005515=PMID:19914168, GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_12627, GO:0005634=PMID:16109376, GO:0005524=GO_REF:0000037, GO:0008353=GO_REF:0000003, GO:0006351=Reactome:REACT_121061, GO:0004672=PMID:7568034, GO:0007219=Reactome:REACT_118859, GO:0045944=Reactome:REACT_120734, GO:0016592=PMID:14638676, GO:0005654=Reactome:REACT_160249, GO:0007179=Reactome:REACT_6844, GO:0004693=GO_REF:0000003} P49336 Cyclin-dependent kinase 8 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0006367=TAS, GO:0005634=IDA, GO:0005524=IEA, GO:0008353=IEA, GO:0006351=TAS, GO:0004672=TAS, GO:0007219=TAS, GO:0045944=TAS, GO:0016592=IDA, GO:0005654=TAS, GO:0007179=TAS, GO:0004693=IEA} Notch signaling pathway, gene expression, positive regulation of transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway mediator complex, nucleoplasm, nucleus ATP binding, RNA polymerase II carboxy-terminal domain kinase activity, cyclin-dependent protein serine/threonine kinase activity, protein binding, protein kinase activity Human UniProtKB:P24863 CDK9 HPA UniProtKB {GO:0005515=PMID:23455922, GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0071157=PMID:20930849, GO:0006368=Reactome:REACT_1845, GO:0006367=Reactome:REACT_12627, GO:0044212=GO_REF:0000019, GO:0006366=Reactome:REACT_1366, GO:0008283=PMID:8170997, GO:0005634=GO_REF:0000052, GO:0043231=GO_REF:0000052, GO:0005737=GO_REF:0000039, GO:0045944=Reactome:REACT_120734, GO:0016032=Reactome:REACT_6256, GO:0007179=Reactome:REACT_6844, GO:0008024=PMID:15905409, GO:0005730=GO_REF:0000052, GO:0031056=PMID:19844166, GO:0008353=PMID:12721286, GO:0005524=GO_REF:0000037, GO:0008023=PMID:10866664, GO:0003677=PMID:16109376, GO:0006351=Reactome:REACT_121061, GO:0050434=Reactome:REACT_6162, GO:0006281=GO_REF:0000037, GO:0004672=PMID:8170997, GO:0006282=PMID:20493174, GO:0071345=PMID:17956865, GO:0016605=PMID:18250157, GO:0017069=GO_REF:0000019, GO:0006468=PMID:16109376, GO:0005654=Reactome:REACT_121336, GO:0043111=PMID:20930849, GO:0004693=GO_REF:0000003} P50750 Cyclin-dependent kinase 9 protein 20080818 {GO:0005515=IPI, GO:0022415=TAS, GO:0010467=TAS, GO:0071157=IDA, GO:0006368=TAS, GO:0006367=TAS, GO:0044212=IEA, GO:0006366=TAS, GO:0008283=TAS, GO:0005634=IDA, GO:0043231=IDA, GO:0005737=IEA, GO:0045944=TAS, GO:0016032=TAS, GO:0007179=TAS, GO:0008024=IDA, GO:0005730=IDA, GO:0031056=IDA, GO:0008353=IDA, GO:0005524=IEA, GO:0008023=TAS, GO:0003677=IDA, GO:0006351=TAS, GO:0050434=TAS, GO:0006281=IEA, GO:0004672=TAS, GO:0006282=IDA, GO:0071345=IDA, GO:0016605=IDA, GO:0017069=IEA, GO:0006468=IDA, GO:0005654=TAS, GO:0043111=IDA, GO:0004693=IEA} DNA repair, cell proliferation, cellular response to cytokine stimulus, gene expression, negative regulation of cell cycle arrest, positive regulation of transcription from RNA polymerase II promoter, positive regulation of viral transcription, protein phosphorylation, regulation of DNA repair, regulation of histone modification, replication fork arrest, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, viral reproduction, viral reproductive process PML body, cytoplasm, intracellular membrane-bounded organelle, nucleolus, nucleoplasm, nucleus, positive transcription elongation factor complex b, transcription elongation factor complex ATP binding, DNA binding, RNA polymerase II carboxy-terminal domain kinase activity, cyclin-dependent protein serine/threonine kinase activity, protein binding, protein kinase activity, snRNA binding, transcription regulatory region DNA binding Human CDKAL1 BHF-UCL UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0051539=GO_REF:0000037, GO:0005789=GO_REF:0000039, GO:0009451=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0016740=GO_REF:0000037, GO:0008033=GO_REF:0000037} Q5VV42 Threonylcarbamoyladenosine tRNA methylthiotransferase protein 20080225 {GO:0008150=ND, GO:0003674=ND, GO:0051539=IEA, GO:0005789=IEA, GO:0009451=IEA, GO:0005575=ND, GO:0016021=IEA, GO:0046872=IEA, GO:0016740=IEA, GO:0008033=IEA} RNA modification, biological_process, tRNA processing cellular_component, endoplasmic reticulum membrane, integral to membrane 4 iron, 4 sulfur cluster binding, metal ion binding, molecular_function, transferase activity Human CDKL1 PINC UniProtKB {GO:0007507=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000002, GO:0006468=PMID:1639063, GO:0005634=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0004693=GO_REF:0000003} Q00532 Cyclin-dependent kinase-like 1 protein 20030904 {GO:0007507=IEA, GO:0005737=IEA, GO:0004672=IEA, GO:0004674=IEA, GO:0006468=TAS, GO:0005634=IEA, GO:0005524=IEA, GO:0004693=IEA} heart development, protein phosphorylation cytoplasm, nucleus ATP binding, cyclin-dependent protein serine/threonine kinase activity, protein kinase activity, protein serine/threonine kinase activity Human CDKL2 HPA UniProtKB {GO:0007165=PMID:9000130, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000039, GO:0004672=PMID:9000130, GO:0004674=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0007548=PMID:9000130, GO:0005524=GO_REF:0000037, GO:0004693=GO_REF:0000003} Q92772 Cyclin-dependent kinase-like 2 protein 20110516 {GO:0007165=TAS, GO:0005813=IDA, GO:0005737=IEA, GO:0004672=TAS, GO:0004674=IEA, GO:0005634=IDA, GO:0007548=TAS, GO:0005524=IEA, GO:0004693=IEA} sex differentiation, signal transduction centrosome, cytoplasm, nucleus ATP binding, cyclin-dependent protein serine/threonine kinase activity, protein kinase activity, protein serine/threonine kinase activity Human CDKL3 PINC UniProtKB {GO:0005737=GO_REF:0000039, GO:0004672=PMID:10463609, GO:0004674=GO_REF:0000002, GO:0016301=GO_REF:0000038, GO:0005524=GO_REF:0000037, GO:0006464=PMID:10463609, GO:0004693=GO_REF:0000003} Q8IVW4 Cyclin-dependent kinase-like 3 protein 20061106 {GO:0005737=IEA, GO:0004672=TAS, GO:0004674=IEA, GO:0016301=IEA, GO:0005524=IEA, GO:0006464=TAS, GO:0004693=IEA} cellular protein modification process cytoplasm ATP binding, cyclin-dependent protein serine/threonine kinase activity, kinase activity, protein kinase activity, protein serine/threonine kinase activity Human CDKL5 HPA UniProtKB {GO:0005730=GO_REF:0000052, GO:0045773=GO_REF:0000024, GO:0032839=GO_REF:0000024, GO:0032587=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0044294=GO_REF:0000024, GO:0005524=PMID:16935860, GO:0032855=GO_REF:0000024, GO:0048365=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0004672=PMID:16935860, GO:0046777=PMID:16935860, GO:0004674=PMID:9721213, GO:0016301=PMID:15917271, GO:0050775=GO_REF:0000024, GO:0050773=GO_REF:0000024, GO:0006468=PMID:9721213, GO:0001764=GO_REF:0000024, GO:0004693=GO_REF:0000003} O76039 Cyclin-dependent kinase-like 5 protein 20101115 {GO:0005730=IDA, GO:0045773=ISS, GO:0032839=ISS, GO:0032587=ISS, GO:0005634=IDA, GO:0044294=ISS, GO:0005524=IDA, GO:0032855=ISS, GO:0048365=ISS, GO:0005737=IDA, GO:0004672=IDA, GO:0046777=IDA, GO:0004674=TAS, GO:0016301=IDA, GO:0050775=ISS, GO:0050773=ISS, GO:0006468=TAS, GO:0001764=ISS, GO:0004693=IEA} neuron migration, positive regulation of Rac GTPase activity, positive regulation of axon extension, positive regulation of dendrite morphogenesis, protein autophosphorylation, protein phosphorylation, regulation of dendrite development cytoplasm, dendrite cytoplasm, dendritic growth cone, nucleolus, nucleus, ruffle membrane ATP binding, Rac GTPase binding, cyclin-dependent protein serine/threonine kinase activity, kinase activity, protein kinase activity, protein serine/threonine kinase activity Human CDKN1A BHF-UCL UniProtKB {GO:0005515=PMID:15232106, GO:0030308=PMID:10208428, GO:0046685=GO_REF:0000019, GO:0008285=PMID:18850004, GO:0030890=GO_REF:0000019, GO:0045736=GO_REF:0000019, GO:0019912=PMID:9106657, GO:0031100=GO_REF:0000019, GO:0007265=PMID:9054499, GO:0005634=PMID:11343236, GO:0048146=PMID:17420273, GO:0000079=PMID:8242751, GO:0090400=PMID:20160708, GO:0032403=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_9068, GO:0000084=Reactome:REACT_899, GO:0000082=PMID:10208428, GO:0043068=GO_REF:0000019, GO:0031668=PMID:17553787, GO:0000086=PMID:17553787, GO:0070557=PMID:18794347, GO:0033158=GO_REF:0000019, GO:0007050=PMID:17553787, GO:0000080=Reactome:REACT_1590, GO:0009411=GO_REF:0000019, GO:0006977=PMID:15149599, GO:0051412=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0030332=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0010243=GO_REF:0000019, GO:0009636=GO_REF:0000019, GO:0071479=PMID:20160708, GO:0006974=PMID:20160708, GO:0097193=PMID:9660939, GO:0042326=PMID:10208428, GO:0071850=GO_REF:0000019, GO:0000307=PMID:17420273, GO:0010629=GO_REF:0000019, GO:0055093=GO_REF:0000019, GO:0004861=GO_REF:0000019, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_111248, GO:0000278=Reactome:REACT_152, GO:2000379=PMID:20160708, GO:2000278=GO_REF:0000019, GO:0090398=PMID:15149599} P38936 Cyclin-dependent kinase inhibitor 1 protein 20090804 {GO:0005515=IPI, GO:0030308=IDA, GO:0046685=IEA, GO:0008285=IMP, GO:0030890=IEA, GO:0045736=IEA, GO:0019912=IDA, GO:0031100=IEA, GO:0007265=IEP, GO:0005634=IDA, GO:0048146=IMP, GO:0000079=TAS, GO:0090400=TAS, GO:0032403=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0000084=TAS, GO:0000082=IDA, GO:0043068=IEA, GO:0031668=IMP, GO:0000086=IMP, GO:0070557=IDA, GO:0033158=IEA, GO:0007050=IMP, GO:0000080=TAS, GO:0009411=IEA, GO:0006977=IDA, GO:0051412=IEA, GO:0043066=IEA, GO:0030332=IEA, GO:0042493=IEA, GO:0010243=IEA, GO:0009636=IEA, GO:0071479=IMP, GO:0006974=IMP, GO:0097193=TAS, GO:0042326=IDA, GO:0071850=IEA, GO:0000307=IDA, GO:0010629=IEA, GO:0055093=IEA, GO:0004861=IEA, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:2000379=IMP, GO:2000278=IEA, GO:0090398=IMP} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, G2/M transition of mitotic cell cycle, Ras protein signal transduction, S phase of mitotic cell cycle, cell cycle arrest, cell cycle checkpoint, cellular response to extracellular stimulus, cellular response to ionizing radiation, cellular senescence, intrinsic apoptotic signaling pathway, mitotic cell cycle, mitotic cell cycle arrest, negative regulation of apoptotic process, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of cyclin-dependent protein serine/threonine kinase activity, negative regulation of gene expression, negative regulation of phosphorylation, organ regeneration, positive regulation of B cell proliferation, positive regulation of fibroblast proliferation, positive regulation of programmed cell death, positive regulation of reactive oxygen species metabolic process, regulation of DNA biosynthetic process, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of protein import into nucleus, translocation, response to DNA damage stimulus, response to UV, response to arsenic-containing substance, response to corticosterone stimulus, response to drug, response to hyperoxia, response to organic nitrogen, response to toxic substance, stress-induced premature senescence PCNA-p21 complex, cyclin-dependent protein kinase holoenzyme complex, cytosol, nucleoplasm, nucleus cyclin binding, cyclin-dependent protein kinase activating kinase activity, cyclin-dependent protein serine/threonine kinase inhibitor activity, metal ion binding, protein binding, protein complex binding Human CDKN1B BHF-UCL UniProtKB {GO:0060770=GO_REF:0000019, GO:0005515=PMID:23455922, GO:0048102=PMID:12698196, GO:0030308=PMID:10208428, GO:0045732=PMID:19056892, GO:0008284=GO_REF:0000019, GO:0008285=PMID:19838216, GO:0045736=GO_REF:0000019, GO:0007605=GO_REF:0000019, GO:0005634=PMID:11800646, GO:0000079=PMID:8033212, GO:0005829=Reactome:REACT_147868, GO:0000084=Reactome:REACT_899, GO:0000082=PMID:10208428, GO:0005737=PMID:12093740, GO:0007173=Reactome:REACT_9417, GO:0007050=PMID:12093740, GO:0000080=Reactome:REACT_1590, GO:0006813=GO_REF:0000019, GO:0010942=PMID:19266349, GO:0071236=GO_REF:0000019, GO:0006977=Reactome:REACT_1625, GO:0071285=PMID:19056892, GO:0033673=PMID:19170105, GO:0043066=GO_REF:0000019, GO:0031116=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0048839=GO_REF:0000019, GO:0006919=PMID:19266349, GO:0019903=PMID:19838216, GO:0048015=Reactome:REACT_12464, GO:0006917=PMID:10208428, GO:0008656=PMID:19266349, GO:0042326=PMID:10208428, GO:0005072=PMID:8033212, GO:0071850=PMID:19266349, GO:0071407=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0045930=PMID:19266349, GO:0045087=Reactome:REACT_6802, GO:0004861=GO_REF:0000019, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_111248, GO:0000278=Reactome:REACT_152, GO:0051271=GO_REF:0000019, GO:0045892=PMID:19170105, GO:0005768=GO_REF:0000039} P46527 Cyclin-dependent kinase inhibitor 1B protein 20071120 {GO:0060770=IEA, GO:0005515=IPI, GO:0048102=IDA, GO:0030308=IDA, GO:0045732=IDA, GO:0008284=IEA, GO:0008285=IMP, GO:0045736=IEA, GO:0007605=IEA, GO:0005634=IDA, GO:0000079=TAS, GO:0005829=TAS, GO:0000084=TAS, GO:0000082=IDA, GO:0005737=IDA, GO:0007173=TAS, GO:0007050=IMP, GO:0000080=TAS, GO:0006813=IEA, GO:0010942=IDA, GO:0071236=IEA, GO:0006977=TAS, GO:0071285=IDA, GO:0033673=IDA, GO:0043066=IEA, GO:0031116=IEA, GO:0048011=TAS, GO:0048839=IEA, GO:0006919=IDA, GO:0019903=IPI, GO:0048015=TAS, GO:0006917=IDA, GO:0008656=IDA, GO:0042326=IDA, GO:0005072=TAS, GO:0071850=IDA, GO:0071407=IEA, GO:0008543=TAS, GO:0045930=IDA, GO:0045087=TAS, GO:0004861=IEA, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0051271=IEA, GO:0045892=IDA, GO:0005768=IEA} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, activation of cysteine-type endopeptidase activity involved in apoptotic process, autophagic cell death, cell cycle arrest, cell cycle checkpoint, cellular response to antibiotic, cellular response to lithium ion, cellular response to organic cyclic compound, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, induction of apoptosis, innate immune response, inner ear development, mitotic cell cycle, mitotic cell cycle arrest, negative regulation of apoptotic process, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of cellular component movement, negative regulation of cyclin-dependent protein serine/threonine kinase activity, negative regulation of epithelial cell proliferation involved in prostate gland development, negative regulation of kinase activity, negative regulation of mitotic cell cycle, negative regulation of phosphorylation, negative regulation of transcription, DNA-dependent, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of cell death, positive regulation of cell proliferation, positive regulation of microtubule polymerization, positive regulation of protein catabolic process, potassium ion transport, regulation of cyclin-dependent protein serine/threonine kinase activity, sensory perception of sound cytoplasm, cytosol, endosome, nucleoplasm, nucleus cyclin-dependent protein serine/threonine kinase inhibitor activity, cysteine-type endopeptidase activator activity involved in apoptotic process, protein binding, protein phosphatase binding, transforming growth factor beta receptor, cytoplasmic mediator activity Human CDKN1C HPA UniProtKB {GO:0005515=PMID:22634751, GO:0033673=PMID:19170105, GO:0008285=PMID:7729684, GO:0042551=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0050680=PMID:16943770, GO:0005634=GO_REF:0000052, GO:0000122=GO_REF:0000019, GO:0001890=GO_REF:0000019, GO:0000079=PMID:7729684, GO:0042326=PMID:19170105, GO:0005737=GO_REF:0000052, GO:0004861=GO_REF:0000002, GO:0007050=GO_REF:0000002, GO:0045893=PMID:19170105, GO:0000080=PMID:7729684, GO:0045892=PMID:19170105, GO:0030511=PMID:16943770} P49918 Cyclin-dependent kinase inhibitor 1C protein 20080205 {GO:0005515=IPI, GO:0033673=IDA, GO:0008285=TAS, GO:0042551=IEA, GO:0005730=IDA, GO:0050680=IMP, GO:0005634=IDA, GO:0000122=IEA, GO:0001890=IEA, GO:0000079=TAS, GO:0042326=IDA, GO:0005737=IDA, GO:0004861=IEA, GO:0007050=IEA, GO:0045893=IGI, GO:0000080=TAS, GO:0045892=IDA, GO:0030511=IMP} G1 phase of mitotic cell cycle, cell cycle arrest, negative regulation of cell proliferation, negative regulation of epithelial cell proliferation, negative regulation of kinase activity, negative regulation of phosphorylation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, neuron maturation, placenta development, positive regulation of transcription, DNA-dependent, positive regulation of transforming growth factor beta receptor signaling pathway, regulation of cyclin-dependent protein serine/threonine kinase activity cytoplasm, nucleolus, nucleus cyclin-dependent protein serine/threonine kinase inhibitor activity, protein binding Human CDKN2A BHF-UCL UniProtKB {GO:0005515=PMID:17486078, GO:0033088=GO_REF:0000024, GO:0030308=PMID:10208428, GO:0006364=GO_REF:0000037, GO:0035985=PMID:16901784, GO:0035986=PMID:16901784, GO:0070534=PMID:18305112, GO:0008637=PMID:12082630, GO:0016301=GO_REF:0000038, GO:0051444=GO_REF:0000024, GO:0055105=GO_REF:0000024, GO:0000209=PMID:18305112, GO:0019901=PMID:8259215, GO:0010389=PMID:15582998, GO:0030889=GO_REF:0000024, GO:0000075=PMID:16243918, GO:0005654=PMID:17110379, GO:0000278=Reactome:REACT_152, GO:0090399=PMID:14720514, GO:0045893=PMID:17569660, GO:0045892=PMID:16901784, GO:0008134=PMID:19057511, GO:0001953=PMID:10205165, GO:0090398=PMID:14966292, GO:0048103=GO_REF:0000024, GO:0008285=PMID:17569660, GO:0045736=PMID:8259215, GO:0007265=PMID:9054499, GO:0005634=PMID:11800646, GO:0005829=Reactome:REACT_7947, GO:0005739=GO_REF:0000039, GO:0031648=PMID:9529249, GO:0000082=PMID:10208428, GO:0005737=PMID:16243918, GO:0031647=GO_REF:0000024, GO:0045944=PMID:17569660, GO:0033235=PMID:19057511, GO:2000774=PMID:16901784, GO:0007050=PMID:15582998, GO:0000080=Reactome:REACT_1590, GO:0051059=PMID:10353611, GO:0006919=PMID:12082630, GO:0005730=PMID:17110379, GO:0032088=PMID:10353611, GO:0006917=PMID:12082630, GO:2000111=PMID:20381282, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0042326=PMID:8259215, GO:0006309=PMID:12082630, GO:0034393=PMID:20381282, GO:0004861=PMID:8259215, GO:0006469=PMID:15582998} Q8N726 Cyclin-dependent kinase inhibitor 2A, isoform 4 protein 20071114 {GO:0005515=IPI, GO:0033088=ISS, GO:0030308=IDA, GO:0006364=IEA, GO:0035985=IDA, GO:0035986=IMP, GO:0070534=IDA, GO:0008637=IMP, GO:0016301=IEA, GO:0051444=ISS, GO:0055105=ISS, GO:0000209=IDA, GO:0019901=IPI, GO:0010389=IMP, GO:0030889=ISS, GO:0000075=IMP, GO:0005654=IDA, GO:0000278=TAS, GO:0090399=IMP, GO:0045893=IDA, GO:0045892=IMP, GO:0008134=IPI, GO:0001953=IMP, GO:0090398=IMP, GO:0048103=ISS, GO:0008285=IDA, GO:0045736=IDA, GO:0007265=IEP, GO:0005634=IDA, GO:0005829=TAS, GO:0005739=IEA, GO:0031648=IDA, GO:0000082=IDA, GO:0005737=IDA, GO:0031647=ISS, GO:0045944=IDA, GO:0033235=IMP, GO:2000774=IMP, GO:0007050=IMP, GO:0000080=TAS, GO:0051059=IDA, GO:0006919=IMP, GO:0005730=IDA, GO:0032088=IDA, GO:0006917=IMP, GO:2000111=ISS, GO:0003677=IEA, GO:0006351=IEA, GO:0042326=IDA, GO:0006309=IMP, GO:0034393=ISS, GO:0004861=IDA, GO:0006469=IMP} G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, Ras protein signal transduction, activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic DNA fragmentation, apoptotic mitochondrial changes, cell cycle arrest, cell cycle checkpoint, cellular senescence, induction of apoptosis, mitotic cell cycle, negative regulation of B cell proliferation, negative regulation of NF-kappaB transcription factor activity, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of cell-matrix adhesion, negative regulation of cyclin-dependent protein serine/threonine kinase activity, negative regulation of immature T cell proliferation in thymus, negative regulation of phosphorylation, negative regulation of protein kinase activity, negative regulation of transcription, DNA-dependent, negative regulation of ubiquitin-protein ligase activity, positive regulation of cellular senescence, positive regulation of macrophage apoptotic process, positive regulation of protein sumoylation, positive regulation of smooth muscle cell apoptotic process, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein K63-linked ubiquitination, protein destabilization, protein polyubiquitination, rRNA processing, regulation of G2/M transition of mitotic cell cycle, regulation of protein stability, replicative senescence, senescence-associated heterochromatin focus assembly, somatic stem cell division, transcription, DNA-dependent cytoplasm, cytosol, mitochondrion, nucleolus, nucleoplasm, nucleus, senescence-associated heterochromatin focus DNA binding, NF-kappaB binding, cyclin-dependent protein serine/threonine kinase inhibitor activity, kinase activity, protein binding, protein kinase binding, transcription factor binding, ubiquitin-protein ligase inhibitor activity Human CDKN2AIP BHF-UCL UniProtKB {GO:0005515=PMID:12581788, GO:0003725=GO_REF:0000002, GO:0002039=PMID:15109303, GO:0030308=PMID:15109303, GO:0031647=PMID:12154087, GO:0001652=PMID:12154087, GO:0005730=PMID:12154087, GO:0009967=PMID:15109303, GO:0005654=PMID:12154087} Q9NXV6 CDKN2A-interacting protein protein 20090630 {GO:0005515=IPI, GO:0003725=IEA, GO:0002039=IDA, GO:0030308=IMP, GO:0031647=IMP, GO:0001652=IDA, GO:0005730=IDA, GO:0009967=IMP, GO:0005654=IDA} negative regulation of cell growth, positive regulation of signal transduction, regulation of protein stability granular component, nucleolus, nucleoplasm double-stranded RNA binding, p53 binding, protein binding Human CDKN2AIPNL null null {} null null null null {} null null null CDKN2B BHF-UCL UniProtKB {GO:0031670=PMID:17597576, GO:0005515=PMID:23455922, GO:0014070=GO_REF:0000019, GO:0010467=Reactome:REACT_71, GO:0007093=PMID:17553787, GO:0006367=Reactome:REACT_12627, GO:0008285=PMID:17553787, GO:0050680=PMID:16943770, GO:0005634=PMID:18564286, GO:0000079=PMID:8078588, GO:0005829=Reactome:REACT_120757, GO:0005737=PMID:16943770, GO:0030858=GO_REF:0000019, GO:0000086=PMID:17553787, GO:0045944=Reactome:REACT_120734, GO:0031668=PMID:17553787, GO:0007179=Reactome:REACT_6844, GO:0007050=PMID:17553787, GO:0034097=GO_REF:0000019, GO:0000080=Reactome:REACT_1590, GO:0030511=PMID:16943770, GO:0019901=PMID:8078588, GO:0006351=Reactome:REACT_121061, GO:0042326=PMID:8078588, GO:0030219=PMID:10812241, GO:0004861=PMID:8078588, GO:0000278=Reactome:REACT_152} P42772 Cyclin-dependent kinase 4 inhibitor B protein 20071120 {GO:0031670=IMP, GO:0005515=IPI, GO:0014070=IEA, GO:0010467=TAS, GO:0007093=IMP, GO:0006367=TAS, GO:0008285=IMP, GO:0050680=IMP, GO:0005634=IDA, GO:0000079=IDA, GO:0005829=TAS, GO:0005737=IDA, GO:0030858=IEA, GO:0000086=IMP, GO:0045944=TAS, GO:0031668=IMP, GO:0007179=TAS, GO:0007050=IMP, GO:0034097=IEA, GO:0000080=TAS, GO:0030511=IMP, GO:0019901=IPI, GO:0006351=TAS, GO:0042326=IDA, GO:0030219=IEP, GO:0004861=IDA, GO:0000278=TAS} G1 phase of mitotic cell cycle, G2/M transition of mitotic cell cycle, cell cycle arrest, cellular response to extracellular stimulus, cellular response to nutrient, gene expression, megakaryocyte differentiation, mitotic cell cycle, mitotic cell cycle checkpoint, negative regulation of cell proliferation, negative regulation of epithelial cell proliferation, negative regulation of phosphorylation, positive regulation of epithelial cell differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transforming growth factor beta receptor signaling pathway, regulation of cyclin-dependent protein serine/threonine kinase activity, response to cytokine stimulus, response to organic cyclic compound, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway cytoplasm, cytosol, nucleus cyclin-dependent protein serine/threonine kinase inhibitor activity, protein binding, protein kinase binding Human CDKN2C BHF-UCL UniProtKB {GO:0030308=PMID:10208428, GO:0008285=PMID:10208428, GO:0019901=PMID:8001816, GO:0048709=GO_REF:0000019, GO:0005634=PMID:11800646, GO:0006917=PMID:10208428, GO:0000079=PMID:8001816, GO:0005829=Reactome:REACT_7947, GO:0042326=PMID:10208428, GO:0000082=PMID:10208428, GO:0005737=PMID:11800646, GO:0004861=PMID:8001816, GO:0007050=PMID:10208428, GO:0000080=Reactome:REACT_1590, GO:0000278=Reactome:REACT_152} P42773 Cyclin-dependent kinase 4 inhibitor C protein 20071120 {GO:0030308=IDA, GO:0008285=IDA, GO:0019901=IPI, GO:0048709=IEA, GO:0005634=IDA, GO:0006917=IDA, GO:0000079=IDA, GO:0005829=TAS, GO:0042326=IDA, GO:0000082=IDA, GO:0005737=IDA, GO:0004861=IDA, GO:0007050=IDA, GO:0000080=TAS, GO:0000278=TAS} G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, cell cycle arrest, induction of apoptosis, mitotic cell cycle, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of phosphorylation, oligodendrocyte differentiation, regulation of cyclin-dependent protein serine/threonine kinase activity cytoplasm, cytosol, nucleus cyclin-dependent protein serine/threonine kinase inhibitor activity, protein kinase binding Human UniProtKB:Q00534 CDKN2D BHF-UCL UniProtKB {GO:0043066=PMID:15750620, GO:0048102=PMID:16322758, GO:0030308=PMID:10208428, GO:0008285=PMID:10208428, GO:0019901=PMID:8741839, GO:0007605=GO_REF:0000019, GO:0033280=PMID:16322758, GO:0005634=PMID:15750620, GO:0000079=PMID:8741839, GO:0005829=Reactome:REACT_7947, GO:0042326=PMID:10208428, GO:0005737=PMID:15750620, GO:0000082=PMID:10208428, GO:0000731=PMID:15750620, GO:0004861=PMID:8741839, GO:0007050=PMID:10208428, GO:0032526=PMID:16322758, GO:0043154=PMID:15750620, GO:0000080=Reactome:REACT_1590, GO:0000278=Reactome:REACT_152, GO:0009411=PMID:15750620} P55273 Cyclin-dependent kinase 4 inhibitor D protein 20071121 {GO:0043066=IMP, GO:0048102=IMP, GO:0030308=IDA, GO:0008285=IDA, GO:0019901=IPI, GO:0007605=IEA, GO:0033280=IMP, GO:0005634=IDA, GO:0000079=IDA, GO:0005829=TAS, GO:0042326=IDA, GO:0005737=IDA, GO:0000082=IDA, GO:0000731=IMP, GO:0004861=IDA, GO:0007050=IDA, GO:0032526=IMP, GO:0043154=IMP, GO:0000080=TAS, GO:0000278=TAS, GO:0009411=IMP} DNA synthesis involved in DNA repair, G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, autophagic cell death, cell cycle arrest, mitotic cell cycle, negative regulation of apoptotic process, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of phosphorylation, regulation of cyclin-dependent protein serine/threonine kinase activity, response to UV, response to retinoic acid, response to vitamin D, sensory perception of sound cytoplasm, cytosol, nucleus cyclin-dependent protein serine/threonine kinase inhibitor activity, protein kinase binding Human CDKN3 GOC UniProtKB {GO:0005515=PMID:11463386, GO:0000082=PMID:8127873, GO:0048471=PMID:10669749, GO:0008285=PMID:8242750, GO:0007050=PMID:8242750, GO:0004722=PMID:12745075, GO:0008138=PMID:8242750, GO:0000079=PMID:8242750, GO:0035335=PMID:8242750, GO:0004725=PMID:8242750} Q16667 Cyclin-dependent kinase inhibitor 3 protein 20130413 {GO:0005515=IPI, GO:0000082=TAS, GO:0048471=IDA, GO:0008285=TAS, GO:0007050=IDA, GO:0004722=IDA, GO:0008138=TAS, GO:0000079=TAS, GO:0035335=IDA, GO:0004725=IDA} G1/S transition of mitotic cell cycle, cell cycle arrest, negative regulation of cell proliferation, peptidyl-tyrosine dephosphorylation, regulation of cyclin-dependent protein serine/threonine kinase activity perinuclear region of cytoplasm protein binding, protein serine/threonine phosphatase activity, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human CDO1 Reactome UniProtKB {GO:0045471=GO_REF:0000019, GO:0006534=PMID:12110289, GO:0051384=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0051591=GO_REF:0000019, GO:0008198=GO_REF:0000019, GO:0005829=Reactome:REACT_115785, GO:0034641=Reactome:REACT_13, GO:0000096=Reactome:REACT_115639, GO:0006954=PMID:12110289, GO:0007595=GO_REF:0000019, GO:0000097=PMID:12110289, GO:0000098=Reactome:REACT_115654, GO:0033762=GO_REF:0000019, GO:0017172=Reactome:REACT_115785, GO:0042412=PMID:12871209, GO:0019448=GO_REF:0000019, GO:0043200=GO_REF:0000019, GO:0055114=PMID:12110289} Q16878 Cysteine dioxygenase type 1 protein 20110929 {GO:0045471=IEA, GO:0006534=TAS, GO:0051384=IEA, GO:0044281=TAS, GO:0051591=IEA, GO:0008198=IEA, GO:0005829=TAS, GO:0034641=TAS, GO:0000096=TAS, GO:0006954=TAS, GO:0007595=IEA, GO:0000097=TAS, GO:0000098=TAS, GO:0033762=IEA, GO:0017172=TAS, GO:0042412=TAS, GO:0019448=IEA, GO:0043200=IEA, GO:0055114=TAS} L-cysteine catabolic process, cellular nitrogen compound metabolic process, cysteine metabolic process, inflammatory response, lactation, oxidation-reduction process, response to amino acid stimulus, response to cAMP, response to ethanol, response to glucagon stimulus, response to glucocorticoid stimulus, small molecule metabolic process, sulfur amino acid biosynthetic process, sulfur amino acid catabolic process, sulfur amino acid metabolic process, taurine biosynthetic process cytosol cysteine dioxygenase activity, ferrous iron binding Human CDON Reactome UniProtKB {GO:0005515=PMID:11782431, GO:0043497=GO_REF:0000019, GO:2000179=GO_REF:0000019, GO:0010172=GO_REF:0000019, GO:0021987=GO_REF:0000019, GO:0005886=Reactome:REACT_21377, GO:0001708=GO_REF:0000019, GO:0051057=GO_REF:0000019, GO:0007520=GO_REF:0000019, GO:0060059=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0048643=GO_REF:0000019, GO:0007224=GO_REF:0000019, GO:0014816=GO_REF:0000019, GO:0042692=Reactome:REACT_21303, GO:0051149=Reactome:REACT_21402, GO:0002088=GO_REF:0000019, GO:0045666=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0001934=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007155=PMID:9214393, GO:0043410=GO_REF:0000019} Q4KMG0 Cell adhesion molecule-related/down-regulated by oncogenes protein 20091030 {GO:0005515=IPI, GO:0043497=IEA, GO:2000179=IEA, GO:0010172=IEA, GO:0021987=IEA, GO:0005886=TAS, GO:0001708=IEA, GO:0051057=IEA, GO:0007520=IEA, GO:0060059=IEA, GO:0009952=IEA, GO:0048643=IEA, GO:0007224=IEA, GO:0014816=IEA, GO:0042692=TAS, GO:0051149=TAS, GO:0002088=IEA, GO:0045666=IEA, GO:0045944=IEA, GO:0001934=IEA, GO:0016021=IEA, GO:0007155=TAS, GO:0043410=IEA} anterior/posterior pattern specification, cell adhesion, cell fate specification, cerebral cortex development, embryonic body morphogenesis, embryonic retina morphogenesis in camera-type eye, lens development in camera-type eye, muscle cell differentiation, myoblast fusion, positive regulation of MAPK cascade, positive regulation of muscle cell differentiation, positive regulation of neural precursor cell proliferation, positive regulation of neuron differentiation, positive regulation of protein phosphorylation, positive regulation of skeletal muscle tissue development, positive regulation of small GTPase mediated signal transduction, positive regulation of transcription from RNA polymerase II promoter, regulation of protein heterodimerization activity, satellite cell differentiation, smoothened signaling pathway integral to membrane, plasma membrane protein binding Human CDR2 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000019, GO:0005634=GO_REF:0000029} Q01850 Cerebellar degeneration-related protein 2 protein 20061026 {GO:0003674=ND, GO:0005737=IEA, GO:0005634=NAS} cytoplasm, nucleus molecular_function Human CDR2L null null {} null null null null {} null null null CDRT15 null null {} null null null null {} null null null CDS1 GOC UniProtKB {GO:0006661=Reactome:REACT_121000, GO:0005783=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0007165=PMID:9115637, GO:0004605=Reactome:REACT_121066, GO:0016024=PMID:9407135, GO:0005789=Reactome:REACT_121066, GO:0016021=GO_REF:0000037, GO:0004142=PMID:9115637, GO:0007602=PMID:9806839, GO:0006644=Reactome:REACT_120870, GO:0006657=PMID:9115637, GO:0046474=Reactome:REACT_121401} Q92903 Phosphatidate cytidylyltransferase 1 protein 20130413 {GO:0006661=TAS, GO:0005783=ISS, GO:0044281=TAS, GO:0007165=NAS, GO:0004605=TAS, GO:0016024=IDA, GO:0005789=TAS, GO:0016021=IEA, GO:0004142=NAS, GO:0007602=NAS, GO:0006644=TAS, GO:0006657=NAS, GO:0046474=TAS} CDP-choline pathway, CDP-diacylglycerol biosynthetic process, glycerophospholipid biosynthetic process, phosphatidylinositol biosynthetic process, phospholipid metabolic process, phototransduction, signal transduction, small molecule metabolic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane diacylglycerol cholinephosphotransferase activity, phosphatidate cytidylyltransferase activity Human CDS2 Reactome UniProtKB {GO:0005783=GO_REF:0000019, GO:0004605=PMID:9806839, GO:0005743=Reactome:REACT_121008, GO:0016024=GO_REF:0000041, GO:0044281=Reactome:REACT_111217, GO:0008654=GO_REF:0000029, GO:0016021=GO_REF:0000029, GO:0006644=Reactome:REACT_120870, GO:0006655=Reactome:REACT_121280, GO:0046474=Reactome:REACT_121401} O95674 Phosphatidate cytidylyltransferase 2 protein 20130301 {GO:0005783=IEA, GO:0004605=NAS, GO:0005743=TAS, GO:0016024=IEA, GO:0044281=TAS, GO:0008654=NAS, GO:0016021=NAS, GO:0006644=TAS, GO:0006655=TAS, GO:0046474=TAS} CDP-diacylglycerol biosynthetic process, glycerophospholipid biosynthetic process, phosphatidylglycerol biosynthetic process, phospholipid biosynthetic process, phospholipid metabolic process, small molecule metabolic process endoplasmic reticulum, integral to membrane, mitochondrial inner membrane phosphatidate cytidylyltransferase activity Human CDSN MGI UniProtKB {GO:0030057=PMID:11279026, GO:0016337=PMID:11739386, GO:0008544=PMID:9395522, GO:0005911=PMID:9395522, GO:0030216=PMID:8415725, GO:0005576=GO_REF:0000039, GO:0043589=PMID:20691404, GO:0007155=PMID:9395522, GO:0042803=PMID:15086562, GO:0001533=PMID:9395522} Q15517 Corneodesmosin protein 20060111 {GO:0030057=IDA, GO:0016337=IDA, GO:0008544=TAS, GO:0005911=TAS, GO:0030216=NAS, GO:0005576=IEA, GO:0043589=IMP, GO:0007155=TAS, GO:0042803=IDA, GO:0001533=IDA} cell adhesion, cell-cell adhesion, epidermis development, keratinocyte differentiation, skin morphogenesis cell-cell junction, cornified envelope, desmosome, extracellular region protein homodimerization activity Human CDT1 HPA UniProtKB {GO:0005515=PMID:20202939, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000024, GO:0005829=Reactome:REACT_1787, GO:0006260=GO_REF:0000037, GO:0000084=Reactome:REACT_899, GO:0000082=Reactome:REACT_1783, GO:0030174=PMID:11125146, GO:0000083=Reactome:REACT_683, GO:0000076=PMID:14672932, GO:0005654=Reactome:REACT_22145, GO:0007090=GO_REF:0000019, GO:0000278=Reactome:REACT_152} Q9H211 DNA replication factor Cdt1 protein 20101115 {GO:0005515=IPI, GO:0005634=IDA, GO:0003677=ISS, GO:0005829=TAS, GO:0006260=IEA, GO:0000084=TAS, GO:0000082=TAS, GO:0030174=IDA, GO:0000083=TAS, GO:0000076=IDA, GO:0005654=TAS, GO:0007090=IEA, GO:0000278=TAS} DNA replication, DNA replication checkpoint, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, mitotic cell cycle, regulation of DNA-dependent DNA replication initiation, regulation of S phase of mitotic cell cycle, regulation of transcription involved in G1/S phase of mitotic cell cycle cytosol, nucleoplasm, nucleus DNA binding, protein binding Human CDV3 HPA UniProtKB {GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0008283=PMID:10497265, GO:0005730=GO_REF:0000052, GO:0005575=GO_REF:0000015} Q9UKY7 Protein CDV3 homolog protein 20111111 {GO:0003674=ND, GO:0005737=IDA, GO:0008283=NAS, GO:0005730=IDA, GO:0005575=ND} cell proliferation cellular_component, cytoplasm, nucleolus molecular_function Human CDX1 PINC UniProtKB {GO:0000976=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0060349=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0009887=PMID:8530027, GO:0005634=GO_REF:0000039, GO:0009952=GO_REF:0000019} P47902 Homeobox protein CDX-1 protein 20031120 {GO:0000976=IEA, GO:0003700=IEA, GO:0060349=IEA, GO:0045944=IEA, GO:0009887=TAS, GO:0005634=IEA, GO:0009952=IEA} anterior/posterior pattern specification, bone morphogenesis, organ morphogenesis, positive regulation of transcription from RNA polymerase II promoter nucleus sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding Human CDX2 PINC UniProtKB {GO:0060711=GO_REF:0000019, GO:0000976=GO_REF:0000002, GO:0000794=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0001568=GO_REF:0000019, GO:0006366=PMID:9459001, GO:0003714=GO_REF:0000019, GO:0045597=GO_REF:0000019, GO:0008333=GO_REF:0000019, GO:0005634=GO_REF:0000040, GO:0000122=GO_REF:0000019, GO:0001829=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0045197=GO_REF:0000019, GO:0017053=GO_REF:0000019, GO:0009887=PMID:9052785, GO:0035019=GO_REF:0000019} Q99626 Homeobox protein CDX-2 protein 20031120 {GO:0060711=IEA, GO:0000976=IEA, GO:0000794=IEA, GO:0003700=IEA, GO:0001568=IEA, GO:0006366=TAS, GO:0003714=IEA, GO:0045597=IEA, GO:0008333=IEA, GO:0005634=IEA, GO:0000122=IEA, GO:0001829=IEA, GO:0009952=IEA, GO:0045197=IEA, GO:0017053=IEA, GO:0009887=TAS, GO:0035019=IEA} anterior/posterior pattern specification, blood vessel development, endosome to lysosome transport, establishment or maintenance of epithelial cell apical/basal polarity, labyrinthine layer development, negative regulation of transcription from RNA polymerase II promoter, organ morphogenesis, positive regulation of cell differentiation, somatic stem cell maintenance, transcription from RNA polymerase II promoter, trophectodermal cell differentiation condensed nuclear chromosome, nucleus, transcriptional repressor complex sequence-specific DNA binding transcription factor activity, transcription corepressor activity, transcription regulatory region sequence-specific DNA binding Human CDX4 UniProtKB UniProtKB {GO:0060711=GO_REF:0000019, GO:0000976=GO_REF:0000002, GO:0001568=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0000122=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0006351=GO_REF:0000037} O14627 Homeobox protein CDX-4 protein 20130413 {GO:0060711=IEA, GO:0000976=IEA, GO:0001568=IEA, GO:0003700=IEA, GO:0005634=IEA, GO:0000122=IEA, GO:0009952=IEA, GO:0006351=IEA} anterior/posterior pattern specification, blood vessel development, labyrinthine layer development, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding Human UniProtKB-SubCell:SL-0191 CDY1 PINC UniProtKB {GO:0005634=GO_REF:0000039, GO:0007283=PMID:9381176, GO:0004402=GO_REF:0000003} Q9Y6F8 Testis-specific chromodomain protein Y 1 protein 20050308 {GO:0005634=IEA, GO:0007283=TAS, GO:0004402=IEA} spermatogenesis nucleus histone acetyltransferase activity Human CDY1B null null {} null null null null {} null null null CDY2A PINC UniProtKB {GO:0005634=GO_REF:0000039, GO:0007283=PMID:9381176, GO:0003824=GO_REF:0000002, GO:0004402=GO_REF:0000003} Q9Y6F7 Testis-specific chromodomain protein Y 2 protein 20030904 {GO:0005634=IEA, GO:0007283=TAS, GO:0003824=IEA, GO:0004402=IEA} spermatogenesis nucleus catalytic activity, histone acetyltransferase activity Human CDY2B null null {} null null null null {} null null null CDYL PINC UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=PMID:18450745, GO:0007283=PMID:10192397, GO:0035064=PMID:18450745, GO:0003824=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0004402=GO_REF:0000003} Q9Y232 Chromodomain Y-like protein protein 20030904 {GO:0006355=IEA, GO:0005634=IDA, GO:0007283=TAS, GO:0035064=IDA, GO:0003824=IEA, GO:0006351=IEA, GO:0004402=IEA} regulation of transcription, DNA-dependent, spermatogenesis, transcription, DNA-dependent nucleus catalytic activity, histone acetyltransferase activity, methylated histone residue binding Human CDYL2 UniProtKB UniProtKB {GO:0005515=PMID:17577209, GO:0005634=GO_REF:0000039, GO:0003824=GO_REF:0000002} Q8N8U2 Chromodomain Y-like protein 2 protein 20090724 {GO:0005515=IPI, GO:0005634=IEA, GO:0003824=IEA} nucleus catalytic activity, protein binding Human UniProtKB:Q9BQA5 CEACAM1 IntAct UniProtKB {GO:0005515=PMID:21982860, GO:0003674=GO_REF:0000015, GO:0005886=Reactome:REACT_12073, GO:0016020=PMID:2457922, GO:0016477=PMID:15687237, GO:0005887=PMID:15687237, GO:0007229=PMID:15687237, GO:0005576=GO_REF:0000039, GO:0016021=PMID:11994468, GO:0001525=PMID:15687237, GO:0007156=PMID:15687237} P13688 Carcinoembryonic antigen-related cell adhesion molecule 1 protein 20130415 {GO:0005515=IPI, GO:0003674=ND, GO:0005886=TAS, GO:0016020=TAS, GO:0016477=NAS, GO:0005887=NAS, GO:0007229=NAS, GO:0005576=IEA, GO:0016021=IDA, GO:0001525=NAS, GO:0007156=NAS} angiogenesis, cell migration, homophilic cell adhesion, integrin-mediated signaling pathway extracellular region, integral to membrane, integral to plasma membrane, membrane, plasma membrane molecular_function, protein binding Human UniProtKB:Q16568 CEACAM21 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q3KPI0 Carcinoembryonic antigen-related cell adhesion molecule 21 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 CEACAM3 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} P40198 Carcinoembryonic antigen-related cell adhesion molecule 3 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 CEACAM5 IntAct UniProtKB {GO:0016323=PMID:15052268, GO:0005887=PMID:3814146, GO:0031225=GO_REF:0000037, GO:0042802=PMID:18086185} P06731 Carcinoembryonic antigen-related cell adhesion molecule 5 protein 20130415 {GO:0016323=IDA, GO:0005887=TAS, GO:0031225=IEA, GO:0042802=IPI} anchored to membrane, basolateral plasma membrane, integral to plasma membrane identical protein binding Human UniProtKB:P06731 CEACAM6 IntAct UniProtKB {GO:0005515=PMID:21982860, GO:0007165=PMID:3220478, GO:0005886=Reactome:REACT_12073, GO:0005887=PMID:3220478, GO:0007267=PMID:3220478, GO:0031225=GO_REF:0000037} P40199 Carcinoembryonic antigen-related cell adhesion molecule 6 protein 20130415 {GO:0005515=IPI, GO:0007165=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0007267=TAS, GO:0031225=IEA} cell-cell signaling, signal transduction anchored to membrane, integral to plasma membrane, plasma membrane protein binding Human UniProtKB:Q16568 CEACAM8 Reactome UniProtKB {GO:0006955=PMID:2208113, GO:0005886=Reactome:REACT_12073, GO:0005887=PMID:2208113, GO:0031225=GO_REF:0000037, GO:0005615=PMID:2306228} P31997 Carcinoembryonic antigen-related cell adhesion molecule 8 protein 20071125 {GO:0006955=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0031225=IEA, GO:0005615=TAS} immune response anchored to membrane, extracellular space, integral to plasma membrane, plasma membrane Human CEBPA IntAct UniProtKB {GO:0005515=PMID:16490787, GO:0003700=PMID:12695546, GO:0008285=GO_REF:0000019, GO:0006366=PMID:8643605, GO:0044212=PMID:12695546, GO:0030324=GO_REF:0000019, GO:0003705=PMID:7575576, GO:0019221=PMID:15664994, GO:0031100=GO_REF:0000019, GO:0005634=PMID:7575576, GO:0006091=PMID:8643605, GO:0032403=GO_REF:0000019, GO:0016363=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0045945=PMID:12695546, GO:0035189=GO_REF:0000019, GO:0030099=PMID:15664994, GO:0030225=GO_REF:0000019, GO:0048469=GO_REF:0000019, GO:0008203=GO_REF:0000019, GO:0071285=GO_REF:0000019, GO:0048839=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0001892=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0006953=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0003677=PMID:8643605, GO:0033274=GO_REF:0000019, GO:0006351=PMID:15664994, GO:0043565=GO_REF:0000002, GO:0045669=GO_REF:0000019, GO:0001889=GO_REF:0000019, GO:0071407=GO_REF:0000019, GO:0050872=GO_REF:0000019, GO:0050873=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0000050=GO_REF:0000019, GO:0045600=GO_REF:0000019, GO:0071837=GO_REF:0000019, GO:0007005=GO_REF:0000019, GO:0008134=PMID:15664994} P49715 CCAAT/enhancer-binding protein alpha protein 20130415 {GO:0005515=IPI, GO:0003700=IDA, GO:0008285=IEA, GO:0006366=TAS, GO:0044212=IDA, GO:0030324=IEA, GO:0003705=NAS, GO:0019221=NAS, GO:0031100=IEA, GO:0005634=NAS, GO:0006091=TAS, GO:0032403=IEA, GO:0016363=IEA, GO:0042803=IEA, GO:0045944=IEA, GO:0045945=IDA, GO:0035189=IEA, GO:0030099=NAS, GO:0030225=IEA, GO:0048469=IEA, GO:0008203=IEA, GO:0071285=IEA, GO:0048839=IEA, GO:0046982=IEA, GO:0001892=IEA, GO:0051384=IEA, GO:0006953=IEA, GO:0000122=IEA, GO:0003677=TAS, GO:0033274=IEA, GO:0006351=IDA, GO:0043565=IEA, GO:0045669=IEA, GO:0001889=IEA, GO:0071407=IEA, GO:0050872=IEA, GO:0050873=IEA, GO:0019048=IEA, GO:0000050=IEA, GO:0045600=IEA, GO:0071837=IEA, GO:0007005=IEA, GO:0008134=IPI} acute-phase response, brown fat cell differentiation, cell maturation, cellular response to lithium ion, cellular response to organic cyclic compound, cholesterol metabolic process, cytokine-mediated signaling pathway, embryonic placenta development, generation of precursor metabolites and energy, inner ear development, liver development, lung development, macrophage differentiation, mitochondrion organization, myeloid cell differentiation, negative regulation of cell proliferation, negative regulation of transcription from RNA polymerase II promoter, organ regeneration, positive regulation of fat cell differentiation, positive regulation of osteoblast differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase III promoter, response to glucocorticoid stimulus, response to vitamin B2, transcription from RNA polymerase II promoter, transcription, DNA-dependent, urea cycle, virus-host interaction, white fat cell differentiation Rb-E2F complex, nuclear matrix, nucleus DNA binding, HMG box domain binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, protein binding, protein complex binding, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding Human UniProtKB:P09874 CEBPB BHF-UCL UniProtKB {GO:0005515=PMID:17724128, GO:0034976=PMID:20829347, GO:0000790=GO_REF:0000019, GO:0003700=PMID:10821850, GO:0006366=PMID:10821850, GO:0003705=GO_REF:0000024, GO:0005634=PMID:20829347, GO:0045408=GO_REF:0000019, GO:0035259=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0016363=GO_REF:0000019, GO:0006955=PMID:2112087, GO:0005737=GO_REF:0000019, GO:0006954=PMID:2112087, GO:0060644=GO_REF:0000019, GO:0071230=GO_REF:0000019, GO:0030182=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0006355=PMID:20829347, GO:0043066=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0001892=GO_REF:0000019, GO:0006917=GO_REF:0000019, GO:0006953=PMID:2112087, GO:0003677=PMID:10821850, GO:0043565=GO_REF:0000019, GO:0045669=GO_REF:0000019, GO:0033598=GO_REF:0000019, GO:0001077=GO_REF:0000019, GO:0050873=GO_REF:0000019, GO:0045892=GO_REF:0000019, GO:0008134=GO_REF:0000019} P17676 CCAAT/enhancer-binding protein beta protein 20080331 {GO:0005515=IPI, GO:0034976=IDA, GO:0000790=IEA, GO:0003700=NAS, GO:0006366=TAS, GO:0003705=ISS, GO:0005634=IDA, GO:0045408=IEA, GO:0035259=IEA, GO:0042803=IEA, GO:0016363=IEA, GO:0006955=TAS, GO:0005737=IEA, GO:0006954=TAS, GO:0060644=IEA, GO:0071230=IEA, GO:0030182=IEA, GO:0032496=IEA, GO:0006355=IDA, GO:0043066=IEA, GO:0046982=IEA, GO:0001892=IEA, GO:0006917=IEA, GO:0006953=TAS, GO:0003677=TAS, GO:0043565=IEA, GO:0045669=IEA, GO:0033598=IEA, GO:0001077=IEA, GO:0050873=IEA, GO:0045892=IEA, GO:0008134=IEA} acute-phase response, brown fat cell differentiation, cellular response to amino acid stimulus, embryonic placenta development, immune response, induction of apoptosis, inflammatory response, mammary gland epithelial cell differentiation, mammary gland epithelial cell proliferation, negative regulation of apoptotic process, negative regulation of transcription, DNA-dependent, neuron differentiation, positive regulation of osteoblast differentiation, regulation of interleukin-6 biosynthetic process, regulation of transcription, DNA-dependent, response to endoplasmic reticulum stress, response to lipopolysaccharide, transcription from RNA polymerase II promoter cytoplasm, nuclear chromatin, nuclear matrix, nucleus DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, glucocorticoid receptor binding, protein binding, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human UniProtKB:Q96RU8 CEBPD PINC UniProtKB {GO:0043565=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0006366=PMID:8314590, GO:0005634=GO_REF:0000039} P49716 CCAAT/enhancer-binding protein delta protein 20030904 {GO:0043565=IEA, GO:0003700=IEA, GO:0006366=TAS, GO:0005634=IEA} transcription from RNA polymerase II promoter nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human CEBPE HPA UniProtKB {GO:0006909=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0046982=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0006952=PMID:8661101, GO:0005634=GO_REF:0000052, GO:0042089=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0042803=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0071222=GO_REF:0000019, GO:0030225=GO_REF:0000019, GO:0042742=GO_REF:0000019} Q15744 CCAAT/enhancer-binding protein epsilon protein 20100326 {GO:0006909=IEA, GO:0003700=IEA, GO:0046982=IEA, GO:0005730=IDA, GO:0006952=TAS, GO:0005634=IDA, GO:0042089=IEA, GO:0006351=IEA, GO:0042803=IEA, GO:0043565=IEA, GO:0071222=IEA, GO:0030225=IEA, GO:0042742=IEA} cellular response to lipopolysaccharide, cytokine biosynthetic process, defense response, defense response to bacterium, macrophage differentiation, phagocytosis, transcription, DNA-dependent nucleolus, nucleus protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity NOT Human CEBPG HPA UniProtKB {GO:0005515=PMID:7665092, GO:0003700=GO_REF:0000002, GO:0006357=PMID:16255782, GO:0046982=PMID:7665092, GO:0016071=GO_REF:0000019, GO:0042267=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0045739=PMID:16255782, GO:0043353=GO_REF:0000024, GO:0003677=PMID:7665092, GO:0043433=PMID:7501458, GO:0006351=GO_REF:0000037, GO:0001889=GO_REF:0000024, GO:0043565=PMID:7665092, GO:0006955=GO_REF:0000024, GO:0051091=PMID:7665092, GO:0003690=GO_REF:0000019, GO:0045078=GO_REF:0000024, GO:0030183=GO_REF:0000024, GO:0043388=PMID:7665092, GO:0008134=PMID:7665092} P53567 CCAAT/enhancer-binding protein gamma protein 20081203 {GO:0005515=IPI, GO:0003700=IEA, GO:0006357=IDA, GO:0046982=IDA, GO:0016071=IEA, GO:0042267=ISS, GO:0005730=IDA, GO:0005634=IDA, GO:0045739=IEP, GO:0043353=ISS, GO:0003677=IDA, GO:0043433=ISS, GO:0006351=IEA, GO:0001889=ISS, GO:0043565=IDA, GO:0006955=ISS, GO:0051091=TAS, GO:0003690=IEA, GO:0045078=ISS, GO:0030183=ISS, GO:0043388=TAS, GO:0008134=IDA} B cell differentiation, enucleate erythrocyte differentiation, immune response, liver development, mRNA metabolic process, natural killer cell mediated cytotoxicity, negative regulation of sequence-specific DNA binding transcription factor activity, positive regulation of DNA binding, positive regulation of DNA repair, positive regulation of interferon-gamma biosynthetic process, positive regulation of sequence-specific DNA binding transcription factor activity, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleolus, nucleus DNA binding, double-stranded DNA binding, protein binding, protein heterodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding NOT Human CEBPZ PINC UniProtKB {GO:0006355=GO_REF:0000037, GO:0006366=PMID:2247079, GO:0005634=GO_REF:0000039, GO:0003677=PMID:2247079} Q03701 CCAAT/enhancer-binding protein zeta protein 20030904 {GO:0006355=IEA, GO:0006366=TAS, GO:0005634=IEA, GO:0003677=TAS} regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter nucleus DNA binding Human CECR1 HPA UniProtKB {GO:0009168=GO_REF:0000002, GO:0005794=GO_REF:0000052, GO:0019239=GO_REF:0000002, GO:0046103=GO_REF:0000033, GO:0043394=PMID:20147294, GO:0007275=PMID:10756095, GO:0005615=PMID:20147294, GO:0031685=PMID:20147294, GO:0042803=PMID:20147294, GO:0005829=GO_REF:0000033, GO:0004000=PMID:20147294, GO:0006154=PMID:20147294, GO:0043103=GO_REF:0000033, GO:0008270=PMID:20147294, GO:0008201=GO_REF:0000037, GO:0008083=PMID:10756095} Q9NZK5 Adenosine deaminase CECR1 protein 20101115 {GO:0009168=IEA, GO:0005794=IDA, GO:0019239=IEA, GO:0046103=IBA, GO:0043394=IDA, GO:0007275=NAS, GO:0005615=IDA, GO:0031685=IDA, GO:0042803=IPI, GO:0005829=IRD, GO:0004000=IDA, GO:0006154=IDA, GO:0043103=IBA, GO:0008270=IDA, GO:0008201=IEA, GO:0008083=NAS} adenosine catabolic process, hypoxanthine salvage, inosine biosynthetic process, multicellular organismal development, purine ribonucleoside monophosphate biosynthetic process Golgi apparatus, cytosol, extracellular space adenosine deaminase activity, adenosine receptor binding, deaminase activity, growth factor activity, heparin binding, protein homodimerization activity, proteoglycan binding, zinc ion binding Human CECR2 HGNC UniProtKB {GO:0000910=PMID:11827465, GO:0006309=PMID:12762840, GO:0005719=GO_REF:0000019, GO:0043044=PMID:15640247, GO:0007010=PMID:11827465, GO:0021915=GO_REF:0000019, GO:0006915=PMID:12762840, GO:0005634=PMID:12762840, GO:0090537=PMID:15640247, GO:0016192=PMID:11827465} Q9BXF3 Cat eye syndrome critical region protein 2 protein 20060721 {GO:0000910=NAS, GO:0006309=TAS, GO:0005719=IEA, GO:0043044=IDA, GO:0007010=NAS, GO:0021915=IEA, GO:0006915=IDA, GO:0005634=IDA, GO:0090537=IDA, GO:0016192=NAS} ATP-dependent chromatin remodeling, apoptotic DNA fragmentation, apoptotic process, cytokinesis, cytoskeleton organization, neural tube development, vesicle-mediated transport CERF complex, nuclear euchromatin, nucleus Human CECR5 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0016787=GO_REF:0000002} Q9BXW7 Cat eye syndrome critical region protein 5 protein 20130413 {GO:0005739=IEA, GO:0016787=IEA} mitochondrion hydrolase activity Human Ensembl:ENSMUSP00000074775 CECR6 null null {} null null null null {} null null null CEL Reactome UniProtKB {GO:0006629=Reactome:REACT_602, GO:0004091=GO_REF:0000033, GO:0006707=PMID:12031288, GO:0004806=PMID:2265692, GO:0044241=Reactome:REACT_9518, GO:0005576=Reactome:REACT_9502, GO:0044281=Reactome:REACT_111217, GO:0050253=GO_REF:0000003, GO:0030157=PMID:1854805, GO:0003824=PMID:2265692, GO:0005615=GO_REF:0000033, GO:0018350=PMID:7578248, GO:0005829=GO_REF:0000033, GO:0009062=PMID:7578248, GO:0030299=PMID:12031288, GO:0005737=GO_REF:0000024, GO:0016787=PMID:2265692, GO:0047372=Reactome:REACT_9502, GO:0006641=PMID:2265692, GO:0046514=GO_REF:0000019, GO:0044258=PMID:7578248, GO:0008201=PMID:7578248, GO:0004771=Reactome:REACT_9468} P19835 Bile salt-activated lipase protein 20070202 {GO:0006629=TAS, GO:0004091=IBA, GO:0006707=IDA, GO:0004806=NAS, GO:0044241=TAS, GO:0005576=TAS, GO:0044281=TAS, GO:0050253=IEA, GO:0030157=IDA, GO:0003824=TAS, GO:0005615=IBA, GO:0018350=NAS, GO:0005829=IBA, GO:0009062=NAS, GO:0030299=NAS, GO:0005737=ISS, GO:0016787=TAS, GO:0047372=TAS, GO:0006641=IC, GO:0046514=IEA, GO:0044258=NAS, GO:0008201=NAS, GO:0004771=TAS} ceramide catabolic process, cholesterol catabolic process, fatty acid catabolic process, intestinal cholesterol absorption, intestinal lipid catabolic process, lipid digestion, lipid metabolic process, pancreatic juice secretion, protein esterification, small molecule metabolic process, triglyceride metabolic process cytoplasm, cytosol, extracellular region, extracellular space acylglycerol lipase activity, carboxylesterase activity, catalytic activity, heparin binding, hydrolase activity, retinyl-palmitate esterase activity, sterol esterase activity, triglyceride lipase activity Human CELA1 UniProtKB UniProtKB {GO:0004252=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0000122=GO_REF:0000019, GO:0061113=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0006954=GO_REF:0000019, GO:0035264=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0031017=GO_REF:0000019, GO:0006508=GO_REF:0000037, GO:0045595=GO_REF:0000019, GO:0016055=GO_REF:0000019} Q9UNI1 Chymotrypsin-like elastase family member 1 protein 20130413 {GO:0004252=IEA, GO:0005576=IEA, GO:0000122=IEA, GO:0061113=IEA, GO:0009791=IEA, GO:0046872=IEA, GO:0006954=IEA, GO:0035264=IEA, GO:0042127=IEA, GO:0045944=IEA, GO:0031017=IEA, GO:0006508=IEA, GO:0045595=IEA, GO:0016055=IEA} Wnt receptor signaling pathway, exocrine pancreas development, inflammatory response, multicellular organism growth, negative regulation of transcription from RNA polymerase II promoter, pancreas morphogenesis, positive regulation of transcription from RNA polymerase II promoter, post-embryonic development, proteolysis, regulation of cell differentiation, regulation of cell proliferation extracellular region metal ion binding, serine-type endopeptidase activity Human UniProtKB-SubCell:SL-0243 CELF1 BHF-UCL UniProtKB {GO:0006397=PMID:8948631, GO:0005515=PMID:16946708, GO:0016246=PMID:10893231, GO:0042835=PMID:10893231, GO:0003723=PMID:16946708, GO:0006376=GO_REF:0000024, GO:0007286=GO_REF:0000019, GO:0005634=PMID:10893231, GO:0009790=PMID:10893231, GO:0003729=PMID:14726956, GO:0003676=GO_REF:0000002, GO:0007281=PMID:10893231, GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0030529=PMID:10893231, GO:0043484=PMID:16946708, GO:0031369=GO_REF:0000019, GO:0040018=GO_REF:0000019, GO:0000900=PMID:10893231} Q92879 CUGBP Elav-like family member 1 protein 20081001 {GO:0006397=TAS, GO:0005515=IPI, GO:0016246=NAS, GO:0042835=IDA, GO:0003723=IDA, GO:0006376=ISS, GO:0007286=IEA, GO:0005634=NAS, GO:0009790=NAS, GO:0003729=IDA, GO:0003676=IEA, GO:0007281=NAS, GO:0005737=IEA, GO:0000166=IEA, GO:0030529=NAS, GO:0043484=IDA, GO:0031369=IEA, GO:0040018=IEA, GO:0000900=NAS} RNA interference, embryo development, germ cell development, mRNA processing, mRNA splice site selection, positive regulation of multicellular organism growth, regulation of RNA splicing, spermatid development cytoplasm, nucleus, ribonucleoprotein complex BRE binding, RNA binding, mRNA binding, nucleic acid binding, nucleotide binding, protein binding, translation initiation factor binding, translation repressor activity, nucleic acid binding Human CELF2 InterPro UniProtKB {GO:0006397=GO_REF:0000037, GO:0006396=PMID:9887331, GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0008016=PMID:9887331, GO:0006376=GO_REF:0000019, GO:0005634=GO_REF:0000039} Q5VZZ6 CUGBP Elav-like family member 2 protein 20130413 {GO:0006397=IEA, GO:0006396=TAS, GO:0005737=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0008016=TAS, GO:0006376=IEA, GO:0005634=IEA} RNA processing, mRNA processing, mRNA splice site selection, regulation of heart contraction cytoplasm, nucleus RNA binding, nucleotide binding Human InterPro:IPR002343 CELF3 UniProtKB UniProtKB {GO:0048026=PMID:15009664, GO:0008380=PMID:17725984, GO:0005737=PMID:17725984, GO:0000166=GO_REF:0000002, GO:0000381=PMID:11158314, GO:0000398=PMID:11158314, GO:0003723=PMID:17725984, GO:0005634=PMID:17725984, GO:0030317=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0003729=PMID:11158314, GO:0003676=GO_REF:0000002} Q5SZQ8 CUGBP Elav-like family member 3 protein 20110725 {GO:0048026=IDA, GO:0008380=IMP, GO:0005737=IDA, GO:0000166=IEA, GO:0000381=IDA, GO:0000398=NAS, GO:0003723=IMP, GO:0005634=IDA, GO:0030317=IEA, GO:0007283=IEA, GO:0003729=NAS, GO:0003676=IEA} RNA splicing, mRNA splicing, via spliceosome, positive regulation of mRNA splicing, via spliceosome, regulation of alternative mRNA splicing, via spliceosome, sperm motility, spermatogenesis cytoplasm, nucleus RNA binding, mRNA binding, nucleic acid binding, nucleotide binding Human CELF4 HPA UniProtKB {GO:0048026=PMID:15009664, GO:0042835=GO_REF:0000024, GO:0006376=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0009790=PMID:10893231, GO:0003676=GO_REF:0000002, GO:0003729=GO_REF:0000019, GO:0007281=PMID:10893231, GO:0005737=GO_REF:0000039, GO:0090394=GO_REF:0000019, GO:0000166=GO_REF:0000002, GO:0000381=PMID:19720736, GO:0000380=PMID:19720736, GO:0000900=PMID:10893231} Q9BZC1 CUGBP Elav-like family member 4 protein 20110516 {GO:0048026=IDA, GO:0042835=ISS, GO:0006376=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0009790=NAS, GO:0003676=IEA, GO:0003729=IEA, GO:0007281=NAS, GO:0005737=IEA, GO:0090394=IEA, GO:0000166=IEA, GO:0000381=IDA, GO:0000380=IDA, GO:0000900=NAS} alternative mRNA splicing, via spliceosome, embryo development, germ cell development, mRNA splice site selection, negative regulation of excitatory postsynaptic membrane potential, positive regulation of mRNA splicing, via spliceosome, regulation of alternative mRNA splicing, via spliceosome cytoplasm, nucleolus, nucleus BRE binding, mRNA binding, nucleic acid binding, nucleotide binding, translation repressor activity, nucleic acid binding NOT Human CELF5 UniProtKB UniProtKB {GO:0006397=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002} Q8N6W0 CUGBP Elav-like family member 5 protein 20130413 {GO:0006397=IEA, GO:0005737=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0003676=IEA} mRNA processing cytoplasm, nucleus RNA binding, nucleic acid binding, nucleotide binding Human UniProtKB-SubCell:SL-0086 CELSR1 UniProtKB UniProtKB {GO:0001736=GO_REF:0000024, GO:0005886=GO_REF:0000002, GO:0007266=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0042249=GO_REF:0000019, GO:0007218=GO_REF:0000002, GO:0032956=GO_REF:0000019, GO:0046983=PMID:9339365, GO:0007626=GO_REF:0000019, GO:0001942=GO_REF:0000019, GO:0007156=GO_REF:0000002, GO:0060490=GO_REF:0000019, GO:0042472=GO_REF:0000019, GO:0004930=PMID:9339365, GO:0090251=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0090179=GO_REF:0000019, GO:0001843=GO_REF:0000024, GO:0045176=GO_REF:0000019, GO:0007417=PMID:10716726, GO:0007186=PMID:9339365, GO:0005887=PMID:9339365, GO:0060489=GO_REF:0000019, GO:0042060=GO_REF:0000019, GO:0060488=GO_REF:0000019, GO:0016021=PMID:10716726, GO:0001764=GO_REF:0000019, GO:0048105=GO_REF:0000019, GO:0004888=PMID:9339365} Q9NYQ6 Cadherin EGF LAG seven-pass G-type receptor 1 protein 20060515 {GO:0001736=ISS, GO:0005886=IEA, GO:0007266=IEA, GO:0009952=IEA, GO:0042249=IEA, GO:0007218=IEA, GO:0032956=IEA, GO:0046983=NAS, GO:0007626=IEA, GO:0001942=IEA, GO:0007156=IEA, GO:0060490=IEA, GO:0042472=IEA, GO:0004930=NAS, GO:0090251=IEA, GO:0005509=IEA, GO:0090179=IEA, GO:0001843=ISS, GO:0045176=IEA, GO:0007417=TAS, GO:0007186=NAS, GO:0005887=TAS, GO:0060489=IEA, GO:0042060=IEA, GO:0060488=IEA, GO:0016021=TAS, GO:0001764=IEA, GO:0048105=IEA, GO:0004888=NAS} G-protein coupled receptor signaling pathway, Rho protein signal transduction, anterior/posterior pattern specification, apical protein localization, central nervous system development, establishment of body hair planar orientation, establishment of planar polarity, establishment of planar polarity of embryonic epithelium, hair follicle development, homophilic cell adhesion, inner ear morphogenesis, lateral sprouting involved in lung morphogenesis, locomotory behavior, neural tube closure, neuron migration, neuropeptide signaling pathway, orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis, planar cell polarity pathway involved in neural tube closure, planar dichotomous subdivision of terminal units involved in lung branching morphogenesis, protein localization involved in establishment of planar polarity, regulation of actin cytoskeleton organization, wound healing integral to membrane, integral to plasma membrane, plasma membrane G-protein coupled receptor activity, calcium ion binding, protein dimerization activity, transmembrane signaling receptor activity Human CELSR2 BHF-UCL UniProtKB {GO:0022407=GO_REF:0000024, GO:0006355=GO_REF:0000024, GO:0005886=GO_REF:0000024, GO:0004930=PMID:10907856, GO:0005509=GO_REF:0000002, GO:0021999=GO_REF:0000024, GO:0048813=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0007186=PMID:10907856, GO:0007218=GO_REF:0000002, GO:0021591=GO_REF:0000019, GO:0016021=PMID:10907856, GO:0016055=GO_REF:0000024, GO:0001764=GO_REF:0000019, GO:0007156=GO_REF:0000024} Q9HCU4 Cadherin EGF LAG seven-pass G-type receptor 2 protein 20071123 {GO:0022407=ISS, GO:0006355=ISS, GO:0005886=ISS, GO:0004930=NAS, GO:0005509=IEA, GO:0021999=ISS, GO:0048813=ISS, GO:0005737=ISS, GO:0007186=NAS, GO:0007218=IEA, GO:0021591=IEA, GO:0016021=NAS, GO:0016055=ISS, GO:0001764=IEA, GO:0007156=ISS} G-protein coupled receptor signaling pathway, Wnt receptor signaling pathway, dendrite morphogenesis, homophilic cell adhesion, neural plate anterior/posterior regionalization, neuron migration, neuropeptide signaling pathway, regulation of cell-cell adhesion, regulation of transcription, DNA-dependent, ventricular system development cytoplasm, integral to membrane, plasma membrane G-protein coupled receptor activity, calcium ion binding Human UniProtKB:Q9QYP2 CELSR3 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0007413=GO_REF:0000019, GO:0007186=PMID:15203201, GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0007218=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0001764=GO_REF:0000019, GO:0007156=GO_REF:0000002} Q9NYQ7 Cadherin EGF LAG seven-pass G-type receptor 3 protein 20130415 {GO:0005515=IPI, GO:0007413=IEA, GO:0007186=TAS, GO:0005886=IEA, GO:0004930=IEA, GO:0007218=IEA, GO:0005509=IEA, GO:0016021=IEA, GO:0001764=IEA, GO:0007156=IEA} G-protein coupled receptor signaling pathway, axonal fasciculation, homophilic cell adhesion, neuron migration, neuropeptide signaling pathway integral to membrane, plasma membrane G-protein coupled receptor activity, calcium ion binding, protein binding Human UniProtKB:P16333 CEMP1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q6PRD7 Cementoblastoma-derived protein 1 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 CEND1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8N111 Cell cycle exit and neuronal differentiation protein 1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 CENPA BHF-UCL UniProtKB {GO:0005515=PMID:21478274, GO:0000780=PMID:11682612, GO:0000236=Reactome:REACT_682, GO:0046982=GO_REF:0000002, GO:0006334=Reactome:REACT_22344, GO:0000132=PMID:19468067, GO:0005634=PMID:7962047, GO:0071459=PMID:11682612, GO:0003677=GO_REF:0000037, GO:0005829=Reactome:REACT_150414, GO:0034080=Reactome:REACT_22186, GO:0051382=PMID:11682612, GO:0019048=GO_REF:0000037, GO:0003682=PMID:7962047, GO:0000087=Reactome:REACT_910, GO:0005654=Reactome:REACT_22217, GO:0000778=PMID:18195732, GO:0000278=Reactome:REACT_152, GO:0000786=GO_REF:0000037, GO:0000090=Reactome:REACT_1275, GO:0000939=GO_REF:0000019, GO:0000775=PMID:11084331} P49450 Histone H3-like centromeric protein A protein 20100106 {GO:0005515=IPI, GO:0000780=IDA, GO:0000236=TAS, GO:0046982=IEA, GO:0006334=TAS, GO:0000132=IMP, GO:0005634=TAS, GO:0071459=IDA, GO:0003677=IEA, GO:0005829=TAS, GO:0034080=TAS, GO:0051382=IDA, GO:0019048=IEA, GO:0003682=TAS, GO:0000087=TAS, GO:0005654=TAS, GO:0000778=IDA, GO:0000278=TAS, GO:0000786=IEA, GO:0000090=TAS, GO:0000939=IEA, GO:0000775=IDA} CENP-A containing nucleosome assembly at centromere, M phase of mitotic cell cycle, establishment of mitotic spindle orientation, kinetochore assembly, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, nucleosome assembly, protein localization to chromosome, centromeric region, virus-host interaction chromosome, centromeric region, condensed chromosome inner kinetochore, condensed nuclear chromosome kinetochore, condensed nuclear chromosome, centromeric region, cytosol, nucleoplasm, nucleosome, nucleus DNA binding, chromatin binding, protein binding, protein heterodimerization activity Human CENPB BHF-UCL UniProtKB {GO:0043565=PMID:11682612, GO:0006355=GO_REF:0000002, GO:0003696=PMID:1893793, GO:0003682=PMID:1893793, GO:0019237=PMID:11682612, GO:0005634=GO_REF:0000039, GO:0000775=PMID:11682612} P07199 Major centromere autoantigen B protein 20091216 {GO:0043565=TAS, GO:0006355=IEA, GO:0003696=NAS, GO:0003682=NAS, GO:0019237=IC, GO:0005634=IEA, GO:0000775=IDA} regulation of transcription, DNA-dependent chromosome, centromeric region, nucleus centromeric DNA binding, chromatin binding, satellite DNA binding, sequence-specific DNA binding Human CENPBD1 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037} B2RD01 CENPB DNA-binding domain-containing protein 1 protein 20130413 {GO:0005634=IEA, GO:0003677=IEA} nucleus DNA binding Human UniProtKB-SubCell:SL-0191 CENPC1 HPA UniProtKB {GO:0000780=PMID:11682612, GO:0000236=Reactome:REACT_682, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0005829=Reactome:REACT_150414, GO:0005737=GO_REF:0000052, GO:0051382=PMID:21529714, GO:0005721=PMID:21529714, GO:0007059=PMID:21529714, GO:0000087=Reactome:REACT_910, GO:0000777=GO_REF:0000039, GO:0000776=PMID:21529714, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q03188 Centromere protein C 1 protein 20120912 {GO:0000780=IDA, GO:0000236=TAS, GO:0005634=IDA, GO:0003677=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0051382=IMP, GO:0005721=IDA, GO:0007059=IMP, GO:0000087=TAS, GO:0000777=IEA, GO:0000776=IDA, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, cell division, chromosome segregation, kinetochore assembly, mitotic anaphase, mitotic cell cycle, mitotic prometaphase centromeric heterochromatin, condensed chromosome kinetochore, condensed nuclear chromosome, centromeric region, cytoplasm, cytosol, kinetochore, nucleus DNA binding Human CENPE HPA UniProtKB {GO:0005515=PMID:9763420, GO:0000236=Reactome:REACT_682, GO:0005634=PMID:9763420, GO:0007079=PMID:1406971, GO:0005829=Reactome:REACT_150414, GO:0019886=Reactome:REACT_121399, GO:0005737=GO_REF:0000052, GO:0051382=PMID:9763420, GO:0000089=PMID:2022189, GO:0015630=GO_REF:0000052, GO:0045860=PMID:12925705, GO:0000087=Reactome:REACT_910, GO:0007018=Reactome:REACT_25201, GO:0005875=GO_REF:0000002, GO:0005874=PMID:7889940, GO:0005819=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0003777=PMID:7889940, GO:0005524=GO_REF:0000037, GO:0000940=PMID:9763420, GO:0007596=Reactome:REACT_604, GO:0000776=PMID:11682612, GO:0000779=PMID:19465021, GO:0043515=PMID:9763420, GO:0000778=GO_REF:0000019, GO:0007080=PMID:9363944, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0000775=PMID:11084331, GO:0051301=GO_REF:0000037} Q02224 Centromere-associated protein E protein 20110516 {GO:0005515=IPI, GO:0000236=TAS, GO:0005634=IMP, GO:0007079=TAS, GO:0005829=TAS, GO:0019886=TAS, GO:0005737=IDA, GO:0051382=NAS, GO:0000089=TAS, GO:0015630=IDA, GO:0045860=IMP, GO:0000087=TAS, GO:0007018=TAS, GO:0005875=IEA, GO:0005874=IDA, GO:0005819=IEA, GO:0007275=IEA, GO:0003777=IMP, GO:0005524=IEA, GO:0000940=TAS, GO:0007596=TAS, GO:0000776=IDA, GO:0000779=IDA, GO:0043515=IDA, GO:0000778=IEA, GO:0007080=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0000775=IDA, GO:0051301=IEA} M phase of mitotic cell cycle, antigen processing and presentation of exogenous peptide antigen via MHC class II, blood coagulation, cell division, kinetochore assembly, microtubule-based movement, mitotic anaphase, mitotic cell cycle, mitotic chromosome movement towards spindle pole, mitotic metaphase, mitotic metaphase plate congression, mitotic prometaphase, multicellular organismal development, positive regulation of protein kinase activity chromosome, centromeric region, condensed chromosome outer kinetochore, condensed chromosome, centromeric region, condensed nuclear chromosome kinetochore, cytoplasm, cytosol, kinetochore, microtubule, microtubule associated complex, microtubule cytoskeleton, nucleus, spindle ATP binding, kinetochore binding, microtubule motor activity, protein binding Human CENPF Reactome UniProtKB {GO:0005515=PMID:17363900, GO:0000236=Reactome:REACT_682, GO:0007094=PMID:12974617, GO:0048471=GO_REF:0000039, GO:0008283=PMID:12507285, GO:0005634=PMID:15494374, GO:0005635=PMID:12154071, GO:0015031=PMID:17600710, GO:0016363=PMID:7542657, GO:0042803=PMID:7642639, GO:0030154=GO_REF:0000037, GO:0005829=Reactome:REACT_150414, GO:0000085=PMID:12154071, GO:0005737=PMID:12974617, GO:0051382=PMID:16252009, GO:0007059=PMID:16252009, GO:0000087=Reactome:REACT_910, GO:0016202=PMID:10373470, GO:0000785=PMID:9891037, GO:0051310=PMID:15870278, GO:0010389=PMID:7651420, GO:0042493=PMID:12467231, GO:0005819=PMID:7651420, GO:0030496=PMID:7651420, GO:0008022=PMID:7642639, GO:0006260=GO_REF:0000037, GO:0000922=PMID:7542657, GO:0000940=PMID:7642639, GO:0045502=PMID:12974617, GO:0007517=GO_REF:0000037, GO:0003682=PMID:9891037, GO:0000776=PMID:17363900, GO:0045120=GO_REF:0000019, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0045892=PMID:15677469, GO:0000775=PMID:11084331, GO:0051301=GO_REF:0000037, GO:0008134=PMID:15677469} P49454 Centromere protein F protein 20130213 {GO:0005515=IPI, GO:0000236=TAS, GO:0007094=NAS, GO:0048471=IEA, GO:0008283=NAS, GO:0005634=IDA, GO:0005635=IDA, GO:0015031=IMP, GO:0016363=IDA, GO:0042803=IPI, GO:0030154=IEA, GO:0005829=TAS, GO:0000085=IMP, GO:0005737=IDA, GO:0051382=NAS, GO:0007059=IMP, GO:0000087=TAS, GO:0016202=ISS, GO:0000785=NAS, GO:0051310=IDA, GO:0010389=IMP, GO:0042493=NAS, GO:0005819=IDA, GO:0030496=IDA, GO:0008022=IPI, GO:0006260=IEA, GO:0000922=IDA, GO:0000940=IDA, GO:0045502=IDA, GO:0007517=IEA, GO:0003682=NAS, GO:0000776=IDA, GO:0045120=IEA, GO:0000278=TAS, GO:0000090=TAS, GO:0045892=IDA, GO:0000775=IDA, GO:0051301=IEA, GO:0008134=IPI} DNA replication, G2 phase of mitotic cell cycle, M phase of mitotic cell cycle, cell differentiation, cell division, cell proliferation, chromosome segregation, kinetochore assembly, metaphase plate congression, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, mitotic spindle assembly checkpoint, muscle organ development, negative regulation of transcription, DNA-dependent, protein transport, regulation of G2/M transition of mitotic cell cycle, regulation of striated muscle tissue development, response to drug chromatin, chromosome, centromeric region, condensed chromosome outer kinetochore, cytoplasm, cytosol, kinetochore, midbody, nuclear envelope, nuclear matrix, nucleus, perinuclear region of cytoplasm, pronucleus, spindle, spindle pole chromatin binding, dynein binding, protein C-terminus binding, protein binding, protein homodimerization activity, transcription factor binding Human CENPH IntAct UniProtKB {GO:0005515=PMID:15713649, GO:0000236=Reactome:REACT_682, GO:0006334=Reactome:REACT_22344, GO:0005634=PMID:11092768, GO:0051383=PMID:11092768, GO:0005829=Reactome:REACT_150414, GO:0034080=Reactome:REACT_22186, GO:0007059=GO_REF:0000002, GO:0000087=Reactome:REACT_910, GO:0000777=GO_REF:0000039, GO:0000776=PMID:11092768, GO:0043515=PMID:11092768, GO:0005654=Reactome:REACT_22217, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000002} Q9H3R5 Centromere protein H protein 20130415 {GO:0005515=IPI, GO:0000236=TAS, GO:0006334=TAS, GO:0005634=IDA, GO:0051383=TAS, GO:0005829=TAS, GO:0034080=TAS, GO:0007059=IEA, GO:0000087=TAS, GO:0000777=IEA, GO:0000776=IDA, GO:0043515=IDA, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} CENP-A containing nucleosome assembly at centromere, M phase of mitotic cell cycle, cell division, chromosome segregation, kinetochore organization, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, nucleosome assembly condensed chromosome kinetochore, cytosol, kinetochore, nucleoplasm, nucleus kinetochore binding, protein binding Human UniProtKB:O14777 CENPI Reactome UniProtKB {GO:0034080=Reactome:REACT_22186, GO:0005515=PMID:20212317, GO:0000236=Reactome:REACT_682, GO:0000087=Reactome:REACT_910, GO:0006334=Reactome:REACT_22344, GO:0000776=PMID:20212317, GO:0005654=Reactome:REACT_22217, GO:0007548=PMID:8921378, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0005829=Reactome:REACT_150414} Q92674 Centromere protein I protein 20100417 {GO:0034080=TAS, GO:0005515=IPI, GO:0000236=TAS, GO:0000087=TAS, GO:0006334=TAS, GO:0000776=IDA, GO:0005654=TAS, GO:0007548=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0005829=TAS} CENP-A containing nucleosome assembly at centromere, M phase of mitotic cell cycle, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, nucleosome assembly, sex differentiation cytosol, kinetochore, nucleoplasm protein binding Human CENPJ IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0005813=PMID:21399614, GO:0007099=PMID:17681131, GO:0019901=PMID:20531387, GO:0005814=PMID:20531387, GO:0005874=GO_REF:0000037, GO:0019904=PMID:11984006, GO:0046599=PMID:20531387, GO:0005829=Reactome:REACT_15470, GO:0046785=PMID:15047868, GO:0015631=PMID:15047868, GO:0000086=Reactome:REACT_2203, GO:0007020=PMID:11003675, GO:0000278=Reactome:REACT_152, GO:0008275=PMID:11003675, GO:0051301=PMID:11003675} Q9HC77 Centromere protein J protein 20130415 {GO:0005515=IPI, GO:0005813=IDA, GO:0007099=IMP, GO:0019901=IPI, GO:0005814=IDA, GO:0005874=IEA, GO:0019904=IPI, GO:0046599=IMP, GO:0005829=TAS, GO:0046785=IMP, GO:0015631=IDA, GO:0000086=TAS, GO:0007020=TAS, GO:0000278=TAS, GO:0008275=NAS, GO:0051301=NAS} G2/M transition of mitotic cell cycle, cell division, centriole replication, microtubule nucleation, microtubule polymerization, mitotic cell cycle, regulation of centriole replication centriole, centrosome, cytosol, gamma-tubulin small complex, microtubule protein binding, protein domain specific binding, protein kinase binding, tubulin binding Human UniProtKB:Q96RK0 CENPK Reactome UniProtKB {GO:0034080=Reactome:REACT_22186, GO:0000236=Reactome:REACT_682, GO:0045944=GO_REF:0000019, GO:0000087=Reactome:REACT_910, GO:0006334=Reactome:REACT_22344, GO:0000777=GO_REF:0000039, GO:0005654=Reactome:REACT_22217, GO:0005634=GO_REF:0000002, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0005829=Reactome:REACT_150414} Q9BS16 Centromere protein K protein 20100417 {GO:0034080=TAS, GO:0000236=TAS, GO:0045944=IEA, GO:0000087=TAS, GO:0006334=TAS, GO:0000777=IEA, GO:0005654=TAS, GO:0005634=IEA, GO:0000278=TAS, GO:0000090=TAS, GO:0005829=TAS} CENP-A containing nucleosome assembly at centromere, M phase of mitotic cell cycle, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, nucleosome assembly, positive regulation of transcription from RNA polymerase II promoter condensed chromosome kinetochore, cytosol, nucleoplasm, nucleus Human CENPL Reactome UniProtKB {GO:0000236=Reactome:REACT_682, GO:0000087=Reactome:REACT_910, GO:0005634=GO_REF:0000039, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0000775=GO_REF:0000039, GO:0005829=Reactome:REACT_150414} Q8N0S6 Centromere protein L protein 20120924 {GO:0000236=TAS, GO:0000087=TAS, GO:0005634=IEA, GO:0000278=TAS, GO:0000090=TAS, GO:0000775=IEA, GO:0005829=TAS} M phase of mitotic cell cycle, mitotic anaphase, mitotic cell cycle, mitotic prometaphase chromosome, centromeric region, cytosol, nucleus Human CENPM Reactome UniProtKB {GO:0000236=Reactome:REACT_682, GO:0000087=Reactome:REACT_910, GO:0000777=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0005829=Reactome:REACT_150414} Q9NSP4 Centromere protein M protein 20120924 {GO:0000236=TAS, GO:0000087=TAS, GO:0000777=IEA, GO:0005634=IEA, GO:0000278=TAS, GO:0000090=TAS, GO:0005829=TAS} M phase of mitotic cell cycle, mitotic anaphase, mitotic cell cycle, mitotic prometaphase condensed chromosome kinetochore, cytosol, nucleus Human CENPN Reactome UniProtKB {GO:0034080=Reactome:REACT_22186, GO:0000236=Reactome:REACT_682, GO:0000087=Reactome:REACT_910, GO:0006334=Reactome:REACT_22344, GO:0000777=GO_REF:0000039, GO:0005654=Reactome:REACT_22217, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0005829=Reactome:REACT_150414} Q96H22 Centromere protein N protein 20100417 {GO:0034080=TAS, GO:0000236=TAS, GO:0000087=TAS, GO:0006334=TAS, GO:0000777=IEA, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0005829=TAS} CENP-A containing nucleosome assembly at centromere, M phase of mitotic cell cycle, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, nucleosome assembly condensed chromosome kinetochore, cytosol, nucleoplasm Human CENPO Reactome UniProtKB {GO:0034080=Reactome:REACT_22186, GO:0000236=Reactome:REACT_682, GO:0007059=GO_REF:0000002, GO:0000087=Reactome:REACT_910, GO:0006334=Reactome:REACT_22344, GO:0000777=GO_REF:0000039, GO:0005654=Reactome:REACT_22217, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0005829=Reactome:REACT_150414, GO:0051301=GO_REF:0000002} Q9BU64 Centromere protein O protein 20100417 {GO:0034080=TAS, GO:0000236=TAS, GO:0007059=IEA, GO:0000087=TAS, GO:0006334=TAS, GO:0000777=IEA, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0005829=TAS, GO:0051301=IEA} CENP-A containing nucleosome assembly at centromere, M phase of mitotic cell cycle, cell division, chromosome segregation, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, nucleosome assembly condensed chromosome kinetochore, cytosol, nucleoplasm Human CENPP Reactome UniProtKB {GO:0034080=Reactome:REACT_22186, GO:0000236=Reactome:REACT_682, GO:0000087=Reactome:REACT_910, GO:0006334=Reactome:REACT_22344, GO:0005654=Reactome:REACT_22217, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0000775=GO_REF:0000039, GO:0005829=Reactome:REACT_150414} Q6IPU0 Centromere protein P protein 20100417 {GO:0034080=TAS, GO:0000236=TAS, GO:0000087=TAS, GO:0006334=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0000775=IEA, GO:0005829=TAS} CENP-A containing nucleosome assembly at centromere, M phase of mitotic cell cycle, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, nucleosome assembly chromosome, centromeric region, cytosol, nucleoplasm Human CENPQ Reactome UniProtKB {GO:0034080=Reactome:REACT_22186, GO:0000236=Reactome:REACT_682, GO:0000087=Reactome:REACT_910, GO:0006334=Reactome:REACT_22344, GO:0005654=Reactome:REACT_22217, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0000775=GO_REF:0000039, GO:0005829=Reactome:REACT_150414} Q7L2Z9 Centromere protein Q protein 20100417 {GO:0034080=TAS, GO:0000236=TAS, GO:0000087=TAS, GO:0006334=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0000775=IEA, GO:0005829=TAS} CENP-A containing nucleosome assembly at centromere, M phase of mitotic cell cycle, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, nucleosome assembly chromosome, centromeric region, cytosol, nucleoplasm Human CENPT Reactome UniProtKB {GO:0005515=PMID:19533040, GO:0000236=Reactome:REACT_682, GO:0051276=PMID:21695110, GO:0046982=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0005829=Reactome:REACT_150414, GO:0051382=PMID:21529714, GO:0007059=PMID:21529714, GO:0000087=Reactome:REACT_910, GO:0000777=GO_REF:0000039, GO:0000776=PMID:21529714, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0000775=PMID:21695110, GO:0051301=GO_REF:0000037} Q96BT3 Centromere protein T protein 20130213 {GO:0005515=IPI, GO:0000236=TAS, GO:0051276=IMP, GO:0046982=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0005829=TAS, GO:0051382=IMP, GO:0007059=IMP, GO:0000087=TAS, GO:0000777=IEA, GO:0000776=IDA, GO:0000278=TAS, GO:0000090=TAS, GO:0000775=IDA, GO:0051301=IEA} M phase of mitotic cell cycle, cell division, chromosome organization, chromosome segregation, kinetochore assembly, mitotic anaphase, mitotic cell cycle, mitotic prometaphase chromosome, centromeric region, condensed chromosome kinetochore, cytosol, kinetochore, nucleus DNA binding, protein binding, protein heterodimerization activity Human CENPV HPA UniProtKB {GO:0016846=GO_REF:0000002, GO:0031508=PMID:18772885, GO:0032467=PMID:18772885, GO:0001667=PMID:19930468, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0051233=PMID:18772885, GO:0034508=PMID:18772885, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0007067=GO_REF:0000037, GO:0015630=PMID:19930468, GO:0000777=GO_REF:0000039, GO:0000776=PMID:18772885, GO:0051301=GO_REF:0000037, GO:0033044=PMID:18772885} Q7Z7K6 Centromere protein V protein 20111111 {GO:0016846=IEA, GO:0031508=IMP, GO:0032467=IMP, GO:0001667=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0051233=IDA, GO:0034508=IMP, GO:0003674=ND, GO:0005737=IDA, GO:0007067=IEA, GO:0015630=IDA, GO:0000777=IEA, GO:0000776=IDA, GO:0051301=IEA, GO:0033044=IMP} ameboidal cell migration, cell division, centromere complex assembly, centromeric heterochromatin assembly, mitosis, positive regulation of cytokinesis, regulation of chromosome organization condensed chromosome kinetochore, cytoplasm, kinetochore, microtubule cytoskeleton, nucleolus, nucleus, spindle midzone carbon-sulfur lyase activity, molecular_function Human CEP120 UniProtKB UniProtKB {GO:0032880=GO_REF:0000019, GO:0005737=GO_REF:0000037, GO:0005813=PMID:21399614, GO:0021987=GO_REF:0000019, GO:0022027=GO_REF:0000019, GO:0032886=GO_REF:0000019, GO:0030953=GO_REF:0000019, GO:0008022=GO_REF:0000019, GO:0022008=GO_REF:0000019} Q8N960 Centrosomal protein of 120 kDa protein 20110517 {GO:0032880=IEA, GO:0005737=IEA, GO:0005813=IDA, GO:0021987=IEA, GO:0022027=IEA, GO:0032886=IEA, GO:0030953=IEA, GO:0008022=IEA, GO:0022008=IEA} astral microtubule organization, cerebral cortex development, interkinetic nuclear migration, neurogenesis, regulation of microtubule-based process, regulation of protein localization centrosome, cytoplasm protein C-terminus binding Human CEP128 UniProtKB UniProtKB {GO:0000922=PMID:21399614, GO:0005814=PMID:21399614} Q6ZU80 Centrosomal protein of 128 kDa protein 20110518 {GO:0000922=IDA, GO:0005814=IDA} centriole, spindle pole Human CEP135 Reactome UniProtKB {GO:0005813=PMID:21399614, GO:0010457=PMID:18851962, GO:0007099=PMID:17681131, GO:0005814=PMID:17681131, GO:0000086=Reactome:REACT_2203, GO:0000278=Reactome:REACT_152, GO:0008022=PMID:18851962, GO:0005829=Reactome:REACT_15470} Q66GS9 Centrosomal protein of 135 kDa protein 20130213 {GO:0005813=IDA, GO:0010457=IMP, GO:0007099=IMP, GO:0005814=IDA, GO:0000086=TAS, GO:0000278=TAS, GO:0008022=IPI, GO:0005829=TAS} G2/M transition of mitotic cell cycle, centriole replication, centriole-centriole cohesion, mitotic cell cycle centriole, centrosome, cytosol protein C-terminus binding Human CEP152 HPA UniProtKB {GO:0005515=PMID:21131973, GO:0051298=PMID:20852615, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0019901=PMID:21059844, GO:0000086=Reactome:REACT_2203, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000278=Reactome:REACT_152, GO:0005829=Reactome:REACT_15470} O94986 Centrosomal protein of 152 kDa protein 20110516 {GO:0005515=IPI, GO:0051298=IMP, GO:0005813=IDA, GO:0005737=IDA, GO:0019901=IPI, GO:0000086=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0000278=TAS, GO:0005829=TAS} G2/M transition of mitotic cell cycle, centrosome duplication, mitotic cell cycle centrosome, cytoplasm, cytosol, nucleolus, nucleus protein binding, protein kinase binding Human CEP164 HPA UniProtKB {GO:0005515=PMID:22863007, GO:0005813=GO_REF:0000052, GO:0005814=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005829=Reactome:REACT_15470, GO:0042384=PMID:17954613, GO:0005737=GO_REF:0000052, GO:0007067=GO_REF:0000037, GO:0006281=GO_REF:0000037, GO:0000086=Reactome:REACT_2203, GO:0000278=Reactome:REACT_152, GO:0051301=GO_REF:0000037} Q9UPV0 Centrosomal protein of 164 kDa protein 20110516 {GO:0005515=IPI, GO:0005813=IDA, GO:0005814=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005829=TAS, GO:0042384=IMP, GO:0005737=IDA, GO:0007067=IEA, GO:0006281=IEA, GO:0000086=TAS, GO:0000278=TAS, GO:0051301=IEA} DNA repair, G2/M transition of mitotic cell cycle, cell division, cilium assembly, mitosis, mitotic cell cycle centriole, centrosome, cytoplasm, cytosol, nucleolus, nucleus protein binding Human CEP170 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0005813=PMID:21399614, GO:0005814=GO_REF:0000039, GO:0005874=GO_REF:0000037, GO:0005819=GO_REF:0000039} Q5SW79 Centrosomal protein of 170 kDa protein 20130415 {GO:0005515=IPI, GO:0005813=IDA, GO:0005814=IEA, GO:0005874=IEA, GO:0005819=IEA} centriole, centrosome, microtubule, spindle protein binding Human UniProtKB:P12520 CEP19 UniProtKB UniProtKB {GO:0000922=PMID:21399614, GO:0005814=PMID:21399614} Q96LK0 Centrosomal protein of 19 kDa protein 20110518 {GO:0000922=IDA, GO:0005814=IDA} centriole, spindle pole Human CEP192 HPA UniProtKB {GO:0005515=PMID:19389623, GO:0051298=PMID:17980596, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0019902=PMID:19389623, GO:0005814=GO_REF:0000039, GO:0000086=Reactome:REACT_2203, GO:0010923=PMID:19389623, GO:0000278=Reactome:REACT_152, GO:0051225=PMID:17980596, GO:0000242=GO_REF:0000019, GO:0005829=Reactome:REACT_15470} Q8TEP8 Centrosomal protein of 192 kDa protein 20110516 {GO:0005515=IPI, GO:0051298=IMP, GO:0005813=IDA, GO:0005737=IDA, GO:0019902=IDA, GO:0005814=IEA, GO:0000086=TAS, GO:0010923=IDA, GO:0000278=TAS, GO:0051225=IMP, GO:0000242=IEA, GO:0005829=TAS} G2/M transition of mitotic cell cycle, centrosome duplication, mitotic cell cycle, negative regulation of phosphatase activity, spindle assembly centriole, centrosome, cytoplasm, cytosol, pericentriolar material phosphatase binding, protein binding Human CEP250 Reactome UniProtKB {GO:0005515=PMID:10880350, GO:0010457=PMID:18851962, GO:0048471=GO_REF:0000039, GO:0005813=PMID:21399614, GO:0005815=PMID:9647649, GO:0019901=PMID:9647649, GO:0005814=PMID:18851962, GO:0008022=PMID:18851962, GO:0005829=Reactome:REACT_15470, GO:0005929=GO_REF:0000037, GO:0043234=PMID:10880350, GO:0030997=PMID:9647649, GO:0008104=PMID:18851962, GO:0000086=Reactome:REACT_2203, GO:0031616=GO_REF:0000019, GO:0005932=GO_REF:0000039, GO:0000278=Reactome:REACT_152} Q9BV73 Centrosome-associated protein CEP250 protein 20130213 {GO:0005515=IPI, GO:0010457=IMP, GO:0048471=IEA, GO:0005813=IDA, GO:0005815=NAS, GO:0019901=IPI, GO:0005814=IDA, GO:0008022=IPI, GO:0005829=TAS, GO:0005929=IEA, GO:0043234=IMP, GO:0030997=IDA, GO:0008104=IMP, GO:0000086=TAS, GO:0031616=IEA, GO:0005932=IEA, GO:0000278=TAS} G2/M transition of mitotic cell cycle, centriole-centriole cohesion, mitotic cell cycle, protein localization, regulation of centriole-centriole cohesion centriole, centrosome, cilium, cytosol, microtubule basal body, microtubule organizing center, perinuclear region of cytoplasm, protein complex, spindle pole centrosome protein C-terminus binding, protein binding, protein kinase binding Human CEP290 IntAct UniProtKB {GO:0005515=PMID:22863007, GO:0005813=PMID:16682973, GO:0060041=GO_REF:0000019, GO:0009986=PMID:12493773, GO:0048793=PMID:16682973, GO:0030916=PMID:16682973, GO:0036038=GO_REF:0000024, GO:0005634=PMID:16682973, GO:0015031=GO_REF:0000024, GO:0005829=Reactome:REACT_15470, GO:0042384=GO_REF:0000024, GO:0005737=PMID:14654843, GO:0000086=Reactome:REACT_2203, GO:0000930=PMID:16682973, GO:0060271=GO_REF:0000024, GO:0051011=PMID:16682973, GO:0032391=PMID:16682973, GO:0005932=GO_REF:0000039, GO:0000278=Reactome:REACT_152, GO:0045893=PMID:16682973, GO:0042462=PMID:16682973, GO:0030902=PMID:16682973} O15078 Centrosomal protein of 290 kDa protein 20130415 {GO:0005515=IPI, GO:0005813=IDA, GO:0060041=IEA, GO:0009986=IDA, GO:0048793=ISS, GO:0030916=ISS, GO:0036038=ISS, GO:0005634=IDA, GO:0015031=ISS, GO:0005829=TAS, GO:0042384=ISS, GO:0005737=IDA, GO:0000086=TAS, GO:0000930=IDA, GO:0060271=ISS, GO:0051011=IDA, GO:0032391=ISS, GO:0005932=IEA, GO:0000278=TAS, GO:0045893=IDA, GO:0042462=ISS, GO:0030902=ISS} G2/M transition of mitotic cell cycle, cilium assembly, cilium morphogenesis, eye photoreceptor cell development, hindbrain development, mitotic cell cycle, otic vesicle formation, positive regulation of transcription, DNA-dependent, pronephros development, protein transport, retina development in camera-type eye TCTN-B9D complex, cell surface, centrosome, cytoplasm, cytosol, gamma-tubulin complex, microtubule basal body, nucleus, photoreceptor connecting cilium microtubule minus-end binding, protein binding Human UniProtKB:Q2M1K9 CEP350 HPA UniProtKB {GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0005819=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q5VT06 Centrosome-associated protein 350 protein 20101115 {GO:0005813=IDA, GO:0005737=IDA, GO:0005819=IEA, GO:0005730=IDA, GO:0005634=IDA} centrosome, cytoplasm, nucleolus, nucleus, spindle Human CEP44 UniProtKB UniProtKB {GO:0005813=PMID:21399614, GO:0000922=PMID:21399614, GO:0005737=GO_REF:0000037, GO:0030496=PMID:21399614} Q9C0F1 Centrosomal protein of 44 kDa protein 20110518 {GO:0005813=IDA, GO:0000922=IDA, GO:0005737=IEA, GO:0030496=TAS} centrosome, cytoplasm, midbody, spindle pole Human CEP55 MGI UniProtKB {GO:0000910=PMID:19638580, GO:0005813=PMID:20186884, GO:0007067=GO_REF:0000037, GO:0005814=GO_REF:0000039, GO:0030496=PMID:20186884, GO:0032154=GO_REF:0000039, GO:0045171=GO_REF:0000019} Q53EZ4 Centrosomal protein of 55 kDa protein 20120203 {GO:0000910=IGI, GO:0005813=IDA, GO:0007067=IEA, GO:0005814=IEA, GO:0030496=IDA, GO:0032154=IEA, GO:0045171=IEA} cytokinesis, mitosis centriole, centrosome, cleavage furrow, intercellular bridge, midbody Human CEP57 HPA UniProtKB {GO:0005515=PMID:20195357, GO:0008017=GO_REF:0000002, GO:0005813=PMID:21399614, GO:0005794=PMID:10942595, GO:0034453=GO_REF:0000002, GO:0043015=GO_REF:0000002, GO:0017134=PMID:12717444, GO:0005874=PMID:12717444, GO:0007286=PMID:12954732, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0042803=PMID:12717444, GO:0005829=Reactome:REACT_15470, GO:0042802=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0008543=PMID:12717444, GO:0000086=Reactome:REACT_2203, GO:0015630=GO_REF:0000052, GO:0051260=GO_REF:0000019, GO:0000278=Reactome:REACT_152, GO:0000060=PMID:12717444} Q86XR8 Centrosomal protein of 57 kDa protein 20090616 {GO:0005515=IPI, GO:0008017=IEA, GO:0005813=IDA, GO:0005794=IDA, GO:0034453=IEA, GO:0043015=IEA, GO:0017134=IPI, GO:0005874=IDA, GO:0007286=ISS, GO:0005730=IDA, GO:0005634=IDA, GO:0042803=IPI, GO:0005829=TAS, GO:0042802=IEA, GO:0005737=IDA, GO:0008543=IPI, GO:0000086=TAS, GO:0015630=IDA, GO:0051260=IEA, GO:0000278=TAS, GO:0000060=ISS} G2/M transition of mitotic cell cycle, fibroblast growth factor receptor signaling pathway, microtubule anchoring, mitotic cell cycle, protein homooligomerization, protein import into nucleus, translocation, spermatid development Golgi apparatus, centrosome, cytoplasm, cytosol, microtubule, microtubule cytoskeleton, nucleolus, nucleus fibroblast growth factor binding, gamma-tubulin binding, identical protein binding, microtubule binding, protein binding, protein homodimerization activity Human CEP57L1 UniProtKB UniProtKB {GO:0008017=GO_REF:0000002, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000037, GO:0005815=GO_REF:0000039, GO:0043015=GO_REF:0000002, GO:0034453=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0005575=GO_REF:0000015, GO:0042802=GO_REF:0000002} Q8IYX8 Centrosomal protein CEP57L1 protein 20061026 {GO:0008017=IEA, GO:0008150=ND, GO:0003674=ND, GO:0005737=IEA, GO:0005815=IEA, GO:0043015=IEA, GO:0034453=IEA, GO:0005874=IEA, GO:0005575=ND, GO:0042802=IEA} biological_process, microtubule anchoring cellular_component, cytoplasm, microtubule, microtubule organizing center gamma-tubulin binding, identical protein binding, microtubule binding, molecular_function Human CEP63 IntAct UniProtKB {GO:0005515=PMID:17043677, GO:0042770=GO_REF:0000024, GO:0000922=GO_REF:0000024, GO:0005813=PMID:21399614, GO:0007067=GO_REF:0000037, GO:0000086=Reactome:REACT_2203, GO:0000077=GO_REF:0000024, GO:0000278=Reactome:REACT_152, GO:0051225=GO_REF:0000024, GO:0005829=Reactome:REACT_15470, GO:0051301=GO_REF:0000037} Q96MT8 Centrosomal protein of 63 kDa protein 20130415 {GO:0005515=IPI, GO:0042770=ISS, GO:0000922=ISS, GO:0005813=IDA, GO:0007067=IEA, GO:0000086=TAS, GO:0000077=ISS, GO:0000278=TAS, GO:0051225=ISS, GO:0005829=TAS, GO:0051301=IEA} DNA damage checkpoint, G2/M transition of mitotic cell cycle, cell division, mitosis, mitotic cell cycle, signal transduction in response to DNA damage, spindle assembly centrosome, cytosol, spindle pole protein binding Human UniProtKB:Q9NRI5 CEP68 UniProtKB UniProtKB {GO:0051297=PMID:18042621, GO:0005813=PMID:21399614, GO:0005737=GO_REF:0000037} Q76N32 Centrosomal protein of 68 kDa protein 20110517 {GO:0051297=IMP, GO:0005813=IDA, GO:0005737=IEA} centrosome organization centrosome, cytoplasm Human CEP70 HPA UniProtKB {GO:0005515=PMID:19060904, GO:0005813=PMID:21399614, GO:0031965=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0000086=Reactome:REACT_2203, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000278=Reactome:REACT_152, GO:0005829=Reactome:REACT_15470} Q8NHQ1 Centrosomal protein of 70 kDa protein 20110516 {GO:0005515=IPI, GO:0005813=IDA, GO:0031965=IDA, GO:0005737=IDA, GO:0000086=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0000278=TAS, GO:0005829=TAS} G2/M transition of mitotic cell cycle, mitotic cell cycle centrosome, cytoplasm, cytosol, nuclear membrane, nucleolus, nucleus protein binding Human CEP72 IntAct UniProtKB {GO:0005515=PMID:21078624, GO:0005813=PMID:21399614, GO:0000086=Reactome:REACT_2203, GO:0007051=PMID:19536135, GO:0000278=Reactome:REACT_152, GO:0033566=PMID:19536135, GO:0005829=Reactome:REACT_15470, GO:0042802=GO_REF:0000019} Q9P209 Centrosomal protein of 72 kDa protein 20130415 {GO:0005515=IPI, GO:0005813=IDA, GO:0000086=TAS, GO:0007051=IMP, GO:0000278=TAS, GO:0033566=IMP, GO:0005829=TAS, GO:0042802=IEA} G2/M transition of mitotic cell cycle, gamma-tubulin complex localization, mitotic cell cycle, spindle organization centrosome, cytosol identical protein binding, protein binding Human UniProtKB:O15265 CEP76 Reactome UniProtKB {GO:0005515=PMID:19460342, GO:0005813=PMID:21399614, GO:0005814=PMID:19460342, GO:0000086=Reactome:REACT_2203, GO:0000278=Reactome:REACT_152, GO:0046599=PMID:19460342, GO:0005829=Reactome:REACT_15470} Q8TAP6 Centrosomal protein of 76 kDa protein 20130213 {GO:0005515=IPI, GO:0005813=IDA, GO:0005814=IDA, GO:0000086=TAS, GO:0000278=TAS, GO:0046599=IMP, GO:0005829=TAS} G2/M transition of mitotic cell cycle, mitotic cell cycle, regulation of centriole replication centriole, centrosome, cytosol protein binding Human CEP78 Reactome UniProtKB {GO:0005813=PMID:21399614, GO:0000086=Reactome:REACT_2203, GO:0000278=Reactome:REACT_152, GO:0005829=Reactome:REACT_15470} Q5JTW2 Centrosomal protein of 78 kDa protein 20130213 {GO:0005813=IDA, GO:0000086=TAS, GO:0000278=TAS, GO:0005829=TAS} G2/M transition of mitotic cell cycle, mitotic cell cycle centrosome, cytosol Human CEP85 UniProtKB UniProtKB {GO:0000922=PMID:21399614, GO:0005813=PMID:21399614, GO:0005737=GO_REF:0000037, GO:0005730=PMID:21399614} Q6P2H3 Centrosomal protein of 85 kDa protein 20110518 {GO:0000922=IDA, GO:0005813=IDA, GO:0005737=IEA, GO:0005730=IDA} centrosome, cytoplasm, nucleolus, spindle pole Human CEP85L UniProtKB UniProtKB {GO:0005813=PMID:21399614, GO:0005737=GO_REF:0000037} Q5SZL2 Centrosomal protein of 85 kDa-like protein 20110518 {GO:0005813=TAS, GO:0005737=IEA} centrosome, cytoplasm Human CEP89 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0000922=PMID:21399614, GO:0005813=PMID:21399614, GO:0005886=GO_REF:0000052} Q96ST8 Centrosomal protein of 89 kDa protein 20110516 {GO:0005737=IDA, GO:0000922=IDA, GO:0005813=IDA, GO:0005886=IDA} centrosome, cytoplasm, plasma membrane, spindle pole Human CEP95 UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0005813=PMID:21399614, GO:0000922=PMID:21399614} Q96GE4 Centrosomal protein of 95 kDa protein 20110518 {GO:0005737=IEA, GO:0005813=IDA, GO:0000922=IDA} centrosome, cytoplasm, spindle pole Human CEP97 HPA UniProtKB {GO:0005515=PMID:21620453, GO:0005516=GO_REF:0000037, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0030030=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q8IW35 Centrosomal protein of 97 kDa protein 20101115 {GO:0005515=IPI, GO:0005516=IEA, GO:0005813=IDA, GO:0005737=IDA, GO:0030030=IEA, GO:0005730=IDA, GO:0005634=IDA} cell projection organization centrosome, cytoplasm, nucleolus, nucleus calmodulin binding, protein binding Human CEPT1 GOC UniProtKB {GO:0006629=PMID:10191259, GO:0006646=Reactome:REACT_120919, GO:0031965=GO_REF:0000039, GO:0004307=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0005789=Reactome:REACT_121214, GO:0016021=GO_REF:0000037, GO:0004142=Reactome:REACT_120896, GO:0006644=Reactome:REACT_120870, GO:0006657=Reactome:REACT_120896, GO:0006656=Reactome:REACT_121238, GO:0046474=Reactome:REACT_121401} Q9Y6K0 Choline/ethanolaminephosphotransferase 1 protein 20130413 {GO:0006629=TAS, GO:0006646=TAS, GO:0031965=IEA, GO:0004307=IEA, GO:0044281=TAS, GO:0046872=IEA, GO:0005789=TAS, GO:0016021=IEA, GO:0004142=TAS, GO:0006644=TAS, GO:0006657=TAS, GO:0006656=TAS, GO:0046474=TAS} CDP-choline pathway, glycerophospholipid biosynthetic process, lipid metabolic process, phosphatidylcholine biosynthetic process, phosphatidylethanolamine biosynthetic process, phospholipid metabolic process, small molecule metabolic process endoplasmic reticulum membrane, integral to membrane, nuclear membrane diacylglycerol cholinephosphotransferase activity, ethanolaminephosphotransferase activity, metal ion binding Human CER1 BHF-UCL UniProtKB {GO:0071773=PMID:16798745, GO:0003419=PMID:19113921, GO:0001657=GO_REF:0000024, GO:0007369=PMID:10049596, GO:0008285=PMID:10049596, GO:0035582=PMID:9660951, GO:2000381=GO_REF:0000024, GO:0023019=PMID:10049596, GO:0030178=GO_REF:0000024, GO:0032926=GO_REF:0000024, GO:0005576=PMID:10049596, GO:0030509=Reactome:REACT_12034, GO:0030282=PMID:19113921, GO:0009952=PMID:10049596, GO:0005615=GO_REF:0000024, GO:0005125=GO_REF:0000037, GO:0042803=GO_REF:0000024, GO:0007399=PMID:9660951, GO:0030514=PMID:10049596, GO:0016015=PMID:9660951, GO:0042074=PMID:10049596, GO:0009948=PMID:10049596, GO:0036122=PMID:9660951, GO:0048263=PMID:9660951} O95813 Cerberus protein 20120221 {GO:0071773=ISS, GO:0003419=ISS, GO:0001657=ISS, GO:0007369=ISS, GO:0008285=ISS, GO:0035582=IDA, GO:2000381=ISS, GO:0023019=ISS, GO:0030178=ISS, GO:0032926=ISS, GO:0005576=ISS, GO:0030509=TAS, GO:0030282=IMP, GO:0009952=ISS, GO:0005615=ISS, GO:0005125=IEA, GO:0042803=ISS, GO:0007399=IMP, GO:0030514=ISS, GO:0016015=IDA, GO:0042074=ISS, GO:0009948=ISS, GO:0036122=IDA, GO:0048263=IMP} BMP signaling pathway, anterior/posterior axis specification, anterior/posterior pattern specification, bone mineralization, cell migration involved in gastrulation, cellular response to BMP stimulus, determination of dorsal identity, gastrulation, growth plate cartilage chondrocyte proliferation, negative regulation of BMP signaling pathway, negative regulation of Wnt receptor signaling pathway, negative regulation of activin receptor signaling pathway, negative regulation of cell proliferation, negative regulation of mesoderm development, nervous system development, sequestering of BMP in extracellular matrix, signal transduction involved in regulation of gene expression, ureteric bud development extracellular region, extracellular space BMP binding, cytokine activity, morphogen activity, protein homodimerization activity Human CERCAM PINC UniProtKB {GO:0005886=PMID:10608765, GO:0007159=PMID:10608765, GO:0006928=PMID:10608765, GO:0005788=GO_REF:0000039, GO:0007155=PMID:10608765, GO:0009103=GO_REF:0000002} Q5T4B2 Probable inactive glycosyltransferase 25 family member 3 protein 20030904 {GO:0005886=NAS, GO:0007159=TAS, GO:0006928=TAS, GO:0005788=IEA, GO:0007155=IDA, GO:0009103=IEA} cell adhesion, cellular component movement, leukocyte cell-cell adhesion, lipopolysaccharide biosynthetic process endoplasmic reticulum lumen, plasma membrane Human CERK HPA UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0000287=PMID:10947957, GO:0006687=Reactome:REACT_116105, GO:0005886=Reactome:REACT_116045, GO:0006672=PMID:19501188, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0007205=GO_REF:0000002, GO:0001729=PMID:19501188, GO:0005739=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0004143=GO_REF:0000002, GO:0016021=PMID:11956206} Q8TCT0 Ceramide kinase protein 20090616 {GO:0006665=TAS, GO:0000287=IDA, GO:0006687=TAS, GO:0005886=TAS, GO:0006672=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0005524=IEA, GO:0007205=IEA, GO:0001729=IDA, GO:0005739=IEA, GO:0005737=IDA, GO:0005543=IEA, GO:0004143=IEA, GO:0016021=IDA} ceramide metabolic process, glycosphingolipid metabolic process, protein kinase C-activating G-protein coupled receptor signaling pathway, small molecule metabolic process, sphingolipid metabolic process cytoplasm, integral to membrane, mitochondrion, nucleus, plasma membrane ATP binding, ceramide kinase activity, diacylglycerol kinase activity, magnesium ion binding, phospholipid binding Human CERS1 BHF-UCL UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0003674=GO_REF:0000015, GO:0000139=GO_REF:0000039, GO:0030148=Reactome:REACT_115810, GO:0005789=Reactome:REACT_19234, GO:0044281=Reactome:REACT_111217, GO:0050291=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0046513=GO_REF:0000024, GO:0043231=GO_REF:0000024} P27544 Ceramide synthase 1 protein 20120828 {GO:0006665=TAS, GO:0003674=ND, GO:0000139=IEA, GO:0030148=TAS, GO:0005789=TAS, GO:0044281=TAS, GO:0050291=ISS, GO:0016021=IEA, GO:0046513=ISS, GO:0043231=ISS} ceramide biosynthetic process, small molecule metabolic process, sphingolipid biosynthetic process, sphingolipid metabolic process Golgi membrane, endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle molecular_function, sphingosine N-acyltransferase activity Human UniProtKB:P27545 CERS2 HPA UniProtKB {GO:0005515=PMID:21988832, GO:0006665=Reactome:REACT_19323, GO:0031965=GO_REF:0000052, GO:0003700=GO_REF:0000002, GO:0005783=GO_REF:0000052, GO:0030148=Reactome:REACT_115810, GO:0044281=Reactome:REACT_111217, GO:0003677=GO_REF:0000002, GO:0043565=GO_REF:0000002, GO:0005789=Reactome:REACT_19234, GO:0016021=GO_REF:0000037, GO:0050291=GO_REF:0000019, GO:0046513=GO_REF:0000019} Q96G23 Ceramide synthase 2 protein 20101115 {GO:0005515=IPI, GO:0006665=TAS, GO:0031965=IDA, GO:0003700=IEA, GO:0005783=IDA, GO:0030148=TAS, GO:0044281=TAS, GO:0003677=IEA, GO:0043565=IEA, GO:0005789=TAS, GO:0016021=IEA, GO:0050291=IEA, GO:0046513=IEA} ceramide biosynthetic process, small molecule metabolic process, sphingolipid biosynthetic process, sphingolipid metabolic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, nuclear membrane DNA binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, sphingosine N-acyltransferase activity Human CERS3 Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0043565=GO_REF:0000002, GO:0031965=GO_REF:0000039, GO:0003700=GO_REF:0000002, GO:0030148=Reactome:REACT_115810, GO:0005789=Reactome:REACT_19234, GO:0005634=GO_REF:0000040, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0050291=GO_REF:0000019} Q8IU89 Ceramide synthase 3 protein 20130301 {GO:0006665=TAS, GO:0043565=IEA, GO:0031965=IEA, GO:0003700=IEA, GO:0030148=TAS, GO:0005789=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0050291=IEA} small molecule metabolic process, sphingolipid biosynthetic process, sphingolipid metabolic process endoplasmic reticulum membrane, integral to membrane, nuclear membrane, nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, sphingosine N-acyltransferase activity Human CERS5 Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0043565=GO_REF:0000002, GO:0031965=GO_REF:0000039, GO:0003700=GO_REF:0000002, GO:0005783=GO_REF:0000019, GO:0030148=Reactome:REACT_115810, GO:0005789=Reactome:REACT_19234, GO:0005634=GO_REF:0000040, GO:0044281=Reactome:REACT_111217, GO:0050291=PMID:16951403, GO:0016021=GO_REF:0000037, GO:0046513=PMID:16951403} Q8N5B7 Ceramide synthase 5 protein 20130301 {GO:0006665=TAS, GO:0043565=IEA, GO:0031965=IEA, GO:0003700=IEA, GO:0005783=IEA, GO:0030148=TAS, GO:0005789=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0050291=IDA, GO:0016021=IEA, GO:0046513=IDA} ceramide biosynthetic process, small molecule metabolic process, sphingolipid biosynthetic process, sphingolipid metabolic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, nuclear membrane, nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, sphingosine N-acyltransferase activity Human CERS6 Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0043565=GO_REF:0000002, GO:0031965=GO_REF:0000039, GO:0003700=GO_REF:0000002, GO:0030148=Reactome:REACT_115810, GO:0005789=Reactome:REACT_19234, GO:0044281=Reactome:REACT_111217, GO:0050291=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0046513=GO_REF:0000019} Q6ZMG9 Ceramide synthase 6 protein 20130301 {GO:0006665=TAS, GO:0043565=IEA, GO:0031965=IEA, GO:0003700=IEA, GO:0030148=TAS, GO:0005789=TAS, GO:0044281=TAS, GO:0050291=IEA, GO:0016021=IEA, GO:0046513=IEA} ceramide biosynthetic process, small molecule metabolic process, sphingolipid biosynthetic process, sphingolipid metabolic process endoplasmic reticulum membrane, integral to membrane, nuclear membrane sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, sphingosine N-acyltransferase activity Human CES1 PINC UniProtKB {GO:0004091=GO_REF:0000033, GO:0016787=GO_REF:0000038, GO:0008152=PMID:1918003, GO:0009636=PMID:1918003, GO:0005788=GO_REF:0000039, GO:0047374=GO_REF:0000003, GO:0080030=GO_REF:0000003, GO:0050253=GO_REF:0000003, GO:0080031=GO_REF:0000003, GO:0080032=GO_REF:0000003} P23141 Liver carboxylesterase 1 protein 20030904 {GO:0004091=IBA, GO:0016787=IEA, GO:0008152=TAS, GO:0009636=TAS, GO:0005788=IEA, GO:0047374=IEA, GO:0080030=IEA, GO:0050253=IEA, GO:0080031=IEA, GO:0080032=IEA} metabolic process, response to toxic substance endoplasmic reticulum lumen carboxylesterase activity, hydrolase activity, methyl indole-3-acetate esterase activity, methyl jasmonate esterase activity, methyl salicylate esterase activity, methylumbelliferyl-acetate deacetylase activity, retinyl-palmitate esterase activity Human CES3 RefGenome UniProtKB {GO:0004091=GO_REF:0000033, GO:0016787=GO_REF:0000038, GO:0005788=GO_REF:0000039, GO:0080030=GO_REF:0000003, GO:0050253=GO_REF:0000003, GO:0080031=GO_REF:0000003, GO:0080032=GO_REF:0000003} Q6UWW8 Carboxylesterase 3 protein 20110225 {GO:0004091=IBA, GO:0016787=IEA, GO:0005788=IEA, GO:0080030=IEA, GO:0050253=IEA, GO:0080031=IEA, GO:0080032=IEA} endoplasmic reticulum lumen carboxylesterase activity, hydrolase activity, methyl indole-3-acetate esterase activity, methyl jasmonate esterase activity, methyl salicylate esterase activity, retinyl-palmitate esterase activity Human PANTHER:PTN000168392 CETN1 UniProtKB UniProtKB {GO:0005515=PMID:20643351, GO:0008026=GO_REF:0000002, GO:0008017=GO_REF:0000019, GO:0005813=PMID:8175926, GO:0005509=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0031683=GO_REF:0000019, GO:0005524=GO_REF:0000002, GO:0034605=GO_REF:0000019, GO:0005737=GO_REF:0000037, GO:0007067=GO_REF:0000037, GO:0000922=PMID:8175926, GO:0032795=GO_REF:0000019, GO:0032391=GO_REF:0000019, GO:0051301=GO_REF:0000037} Q12798 Centrin-1 protein 20120708 {GO:0005515=IPI, GO:0008026=IEA, GO:0008017=IEA, GO:0005813=IDA, GO:0005509=IEA, GO:0003676=IEA, GO:0031683=IEA, GO:0005524=IEA, GO:0034605=IEA, GO:0005737=IEA, GO:0007067=IEA, GO:0000922=IDA, GO:0032795=IEA, GO:0032391=IEA, GO:0051301=IEA} cell division, cellular response to heat, mitosis centrosome, cytoplasm, photoreceptor connecting cilium, spindle pole ATP binding, ATP-dependent helicase activity, G-protein beta/gamma-subunit complex binding, calcium ion binding, heterotrimeric G-protein binding, microtubule binding, nucleic acid binding, protein binding Human UniProtKB:Q9D9W1 CETN2 IntAct UniProtKB {GO:0005515=PMID:21962512, GO:0008026=GO_REF:0000002, GO:0008017=GO_REF:0000019, GO:0005813=PMID:21399614, GO:0032465=PMID:16760425, GO:0007099=PMID:12176356, GO:0005814=PMID:12176356, GO:0005509=PMID:8248209, GO:0071942=PMID:11279143, GO:0007283=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0031683=GO_REF:0000019, GO:0005524=GO_REF:0000002, GO:0005829=Reactome:REACT_15470, GO:0005622=GO_REF:0000054, GO:0007067=PMID:8248209, GO:0032795=GO_REF:0000019, GO:0000086=Reactome:REACT_2203, GO:0032391=GO_REF:0000019, GO:0006289=PMID:15964821, GO:0005932=GO_REF:0000019, GO:0000278=Reactome:REACT_152, GO:0051301=GO_REF:0000037} P41208 Centrin-2 protein 20130415 {GO:0005515=IPI, GO:0008026=IEA, GO:0008017=IEA, GO:0005813=IDA, GO:0032465=IMP, GO:0007099=IMP, GO:0005814=IDA, GO:0005509=NAS, GO:0071942=IDA, GO:0007283=IEA, GO:0003676=IEA, GO:0031683=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0005622=IDA, GO:0007067=NAS, GO:0032795=IEA, GO:0000086=TAS, GO:0032391=IEA, GO:0006289=IDA, GO:0005932=IEA, GO:0000278=TAS, GO:0051301=IEA} G2/M transition of mitotic cell cycle, cell division, centriole replication, mitosis, mitotic cell cycle, nucleotide-excision repair, regulation of cytokinesis, spermatogenesis XPC complex, centriole, centrosome, cytosol, intracellular, microtubule basal body, photoreceptor connecting cilium ATP binding, ATP-dependent helicase activity, G-protein beta/gamma-subunit complex binding, calcium ion binding, heterotrimeric G-protein binding, microtubule binding, nucleic acid binding, protein binding Human UniProtKB:Q01831 CETN3 HPA UniProtKB {GO:0008017=GO_REF:0000019, GO:0005813=PMID:21399614, GO:0007067=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0007098=PMID:9256449, GO:0005814=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0032391=GO_REF:0000019, GO:0005932=GO_REF:0000019, GO:0045111=GO_REF:0000052, GO:0031683=GO_REF:0000019, GO:0051301=GO_REF:0000037} O15182 Centrin-3 protein 20110516 {GO:0008017=IEA, GO:0005813=IDA, GO:0007067=IEA, GO:0005737=IDA, GO:0007098=TAS, GO:0005814=IEA, GO:0005509=IEA, GO:0032391=IEA, GO:0005932=IEA, GO:0045111=IDA, GO:0031683=IEA, GO:0051301=IEA} cell division, centrosome cycle, mitosis centriole, centrosome, cytoplasm, intermediate filament cytoskeleton, microtubule basal body, photoreceptor connecting cilium G-protein beta/gamma-subunit complex binding, calcium ion binding, microtubule binding Human CETP BHF-UCL UniProtKB {GO:0006629=Reactome:REACT_602, GO:0017127=PMID:2833496, GO:0070328=PMID:2833496, GO:0030301=PMID:2833496, GO:0044281=Reactome:REACT_111217, GO:0005615=PMID:3104518, GO:0008289=PMID:3818596, GO:0010874=PMID:16670775, GO:0015914=PMID:2833496, GO:0034364=PMID:3104518, GO:0015485=PMID:2833496, GO:0008203=PMID:2833496, GO:0042632=PMID:2586614, GO:0010745=PMID:16670775, GO:0043691=PMID:7583561, GO:0055088=PMID:3818596, GO:0031210=PMID:2833496, GO:0005576=Reactome:REACT_13803, GO:0005548=PMID:2833496, GO:0031982=PMID:2833496, GO:0006898=Reactome:REACT_6934, GO:0034372=PMID:2833496, GO:0034374=PMID:2833496, GO:0034375=PMID:2586614, GO:0006869=PMID:3818596, GO:0042157=Reactome:REACT_13621, GO:0006641=PMID:2833496, GO:0055091=PMID:2833496, GO:0046470=PMID:2833496, GO:0017129=PMID:2833496, GO:0005319=PMID:2833496} P11597 Cholesteryl ester transfer protein protein 20071220 {GO:0006629=TAS, GO:0017127=IDA, GO:0070328=IDA, GO:0030301=IDA, GO:0044281=TAS, GO:0005615=IDA, GO:0008289=IDA, GO:0010874=IMP, GO:0015914=IDA, GO:0034364=IDA, GO:0015485=IDA, GO:0008203=IDA, GO:0042632=IMP, GO:0010745=IC, GO:0043691=IC, GO:0055088=IDA, GO:0031210=IDA, GO:0005576=TAS, GO:0005548=IDA, GO:0031982=IDA, GO:0006898=TAS, GO:0034372=IDA, GO:0034374=IDA, GO:0034375=IMP, GO:0006869=IDA, GO:0042157=TAS, GO:0006641=IDA, GO:0055091=IDA, GO:0046470=IDA, GO:0017129=IDA, GO:0005319=IDA} cholesterol homeostasis, cholesterol metabolic process, cholesterol transport, high-density lipoprotein particle remodeling, lipid homeostasis, lipid metabolic process, lipid transport, lipoprotein metabolic process, low-density lipoprotein particle remodeling, negative regulation of macrophage derived foam cell differentiation, phosphatidylcholine metabolic process, phospholipid homeostasis, phospholipid transport, receptor-mediated endocytosis, regulation of cholesterol efflux, reverse cholesterol transport, small molecule metabolic process, triglyceride homeostasis, triglyceride metabolic process, very-low-density lipoprotein particle remodeling extracellular region, extracellular space, high-density lipoprotein particle, vesicle cholesterol binding, cholesterol transporter activity, lipid binding, lipid transporter activity, phosphatidylcholine binding, phospholipid transporter activity, triglyceride binding Human CFB Reactome UniProtKB {GO:0006957=Reactome:REACT_8001, GO:0030449=Reactome:REACT_118707, GO:0006956=Reactome:REACT_8024, GO:0005886=Reactome:REACT_118782, GO:0001848=PMID:11367526, GO:0004252=Reactome:REACT_7948, GO:0045087=Reactome:REACT_6802, GO:0006508=GO_REF:0000037, GO:0005576=Reactome:REACT_118727} P00751 Complement factor B protein 20060216 {GO:0006957=TAS, GO:0030449=TAS, GO:0006956=TAS, GO:0005886=TAS, GO:0001848=TAS, GO:0004252=TAS, GO:0045087=TAS, GO:0006508=IEA, GO:0005576=TAS} complement activation, complement activation, alternative pathway, innate immune response, proteolysis, regulation of complement activation extracellular region, plasma membrane complement binding, serine-type endopeptidase activity Human CFD Reactome UniProtKB {GO:0006957=Reactome:REACT_8001, GO:0006956=Reactome:REACT_8024, GO:0004252=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0002576=Reactome:REACT_318, GO:0006508=GO_REF:0000037, GO:0030168=Reactome:REACT_798, GO:0008236=PMID:1374388, GO:0031093=Reactome:REACT_21351, GO:0005576=Reactome:REACT_21351, GO:0005615=GO_REF:0000019} P00746 Complement factor D protein 20130301 {GO:0006957=TAS, GO:0006956=TAS, GO:0004252=IEA, GO:0007596=TAS, GO:0045087=TAS, GO:0002576=TAS, GO:0006508=IEA, GO:0030168=TAS, GO:0008236=TAS, GO:0031093=TAS, GO:0005576=TAS, GO:0005615=IEA} blood coagulation, complement activation, complement activation, alternative pathway, innate immune response, platelet activation, platelet degranulation, proteolysis extracellular region, extracellular space, platelet alpha granule lumen serine-type endopeptidase activity, serine-type peptidase activity Human CFDP1 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0043066=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0008360=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0005575=GO_REF:0000015, GO:0007155=GO_REF:0000019} Q9UEE9 Craniofacial development protein 1 protein 20061106 {GO:0008150=ND, GO:0003674=ND, GO:0043066=IEA, GO:0042127=IEA, GO:0008360=IEA, GO:0007275=IEA, GO:0005575=ND, GO:0007155=IEA} biological_process, cell adhesion, multicellular organismal development, negative regulation of apoptotic process, regulation of cell proliferation, regulation of cell shape cellular_component molecular_function Human CFH BHF-UCL UniProtKB {GO:0005515=PMID:18627465, GO:0006957=GO_REF:0000037, GO:0030449=Reactome:REACT_118707, GO:0006956=PMID:9312129, GO:0045087=Reactome:REACT_6802, GO:0043395=PMID:22471560, GO:0005576=Reactome:REACT_118710, GO:0008201=PMID:22471560, GO:0005615=PMID:9312129} P08603 Complement factor H protein 20121220 {GO:0005515=IPI, GO:0006957=IEA, GO:0030449=TAS, GO:0006956=TAS, GO:0045087=TAS, GO:0043395=IDA, GO:0005576=TAS, GO:0008201=IDA, GO:0005615=TAS} complement activation, complement activation, alternative pathway, innate immune response, regulation of complement activation extracellular region, extracellular space heparan sulfate proteoglycan binding, heparin binding, protein binding Human CFHR1 PINC UniProtKB {GO:0006956=PMID:1711047, GO:0005615=PMID:1711047} Q03591 Complement factor H-related protein 1 protein 20030904 {GO:0006956=TAS, GO:0005615=TAS} complement activation extracellular space Human CFHR2 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} P36980 Complement factor H-related protein 2 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 CFHR3 PINC UniProtKB {GO:0005615=PMID:8428964} Q02985 Complement factor H-related protein 3 protein 20030904 {GO:0005615=TAS} extracellular space Human CFHR4 GOC UniProtKB {GO:0006869=PMID:9038172, GO:0005576=GO_REF:0000039, GO:0005319=PMID:9038172} Q92496 Complement factor H-related protein 4 protein 20130413 {GO:0006869=TAS, GO:0005576=IEA, GO:0005319=TAS} lipid transport extracellular region lipid transporter activity Human CFHR5 UniProtKB UniProtKB {GO:0006957=PMID:11058592, GO:0005576=PMID:11058592} Q9BXR6 Complement factor H-related protein 5 protein 20010921 {GO:0006957=NAS, GO:0005576=NAS} complement activation, alternative pathway extracellular region Human CFI Reactome UniProtKB {GO:0030449=Reactome:REACT_118707, GO:0004252=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0045087=Reactome:REACT_6802, GO:0006958=GO_REF:0000037, GO:0006508=GO_REF:0000037, GO:0005576=Reactome:REACT_118844, GO:0005615=GO_REF:0000039, GO:0046872=GO_REF:0000037, GO:0005044=GO_REF:0000002} P05156 Complement factor I protein 20101013 {GO:0030449=TAS, GO:0004252=IEA, GO:0016020=IEA, GO:0045087=TAS, GO:0006958=IEA, GO:0006508=IEA, GO:0005576=TAS, GO:0005615=IEA, GO:0046872=IEA, GO:0005044=IEA} complement activation, classical pathway, innate immune response, proteolysis, regulation of complement activation extracellular region, extracellular space, membrane metal ion binding, scavenger receptor activity, serine-type endopeptidase activity Human CFL1 IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0030036=PMID:10436159, GO:0001755=GO_REF:0000019, GO:0030010=GO_REF:0000019, GO:0005634=PMID:16130169, GO:0007266=PMID:10436159, GO:0015629=GO_REF:0000002, GO:0016363=GO_REF:0000039, GO:0000910=GO_REF:0000019, GO:0005737=PMID:16130169, GO:0007411=Reactome:REACT_18266, GO:0030836=GO_REF:0000019, GO:0007010=PMID:21834987, GO:0022604=PMID:21834987, GO:0030042=GO_REF:0000002, GO:0043200=GO_REF:0000019, GO:0043066=PMID:16130169, GO:0031258=GO_REF:0000039, GO:0030168=Reactome:REACT_798, GO:0003779=GO_REF:0000037, GO:0032587=GO_REF:0000039, GO:0009615=PMID:16548883, GO:0001842=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0002576=Reactome:REACT_318, GO:0006468=GO_REF:0000019, GO:0030864=GO_REF:0000019, GO:0038096=Reactome:REACT_160123} P23528 Cofilin-1 protein 20130415 {GO:0005515=IPI, GO:0030036=TAS, GO:0001755=IEA, GO:0030010=IEA, GO:0005634=TAS, GO:0007266=TAS, GO:0015629=IEA, GO:0016363=IEA, GO:0000910=IEA, GO:0005737=TAS, GO:0007411=TAS, GO:0030836=IEA, GO:0007010=IMP, GO:0022604=IMP, GO:0030042=IEA, GO:0043200=IEA, GO:0043066=TAS, GO:0031258=IEA, GO:0030168=TAS, GO:0003779=IEA, GO:0032587=IEA, GO:0009615=IEP, GO:0001842=IEA, GO:0007596=TAS, GO:0045087=TAS, GO:0002576=TAS, GO:0006468=IEA, GO:0030864=IEA, GO:0038096=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, Rho protein signal transduction, actin cytoskeleton organization, actin filament depolymerization, axon guidance, blood coagulation, cytokinesis, cytoskeleton organization, establishment of cell polarity, innate immune response, negative regulation of apoptotic process, neural crest cell migration, neural fold formation, platelet activation, platelet degranulation, positive regulation of actin filament depolymerization, protein phosphorylation, regulation of cell morphogenesis, response to amino acid stimulus, response to virus actin cytoskeleton, cortical actin cytoskeleton, cytoplasm, lamellipodium membrane, nuclear matrix, nucleus, ruffle membrane actin binding, protein binding Human UniProtKB:P54253 CFL2 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0005737=GO_REF:0000037, GO:0030042=GO_REF:0000002, GO:0003779=GO_REF:0000037, GO:0015629=GO_REF:0000002, GO:0016363=GO_REF:0000039} Q9Y281 Cofilin-2 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0030042=IEA, GO:0003779=IEA, GO:0015629=IEA, GO:0016363=IEA} actin filament depolymerization actin cytoskeleton, cytoplasm, nuclear matrix actin binding, protein binding Human UniProtKB:P63261 CFLAR GOC UniProtKB {GO:0005515=PMID:9208847, GO:2001237=PMID:22266862, GO:0043066=PMID:18202225, GO:0006915=GO_REF:0000037, GO:1901740=GO_REF:0000024, GO:0014732=GO_REF:0000024, GO:0042981=GO_REF:0000002, GO:0043085=PMID:9208847, GO:0002020=PMID:9208847, GO:0004197=GO_REF:0000002, GO:0005737=PMID:18073330, GO:0007519=GO_REF:0000024, GO:0019048=GO_REF:0000037, GO:0006508=GO_REF:0000002, GO:0043403=GO_REF:0000024, GO:0014842=GO_REF:0000024, GO:0043123=PMID:12761501, GO:0014866=GO_REF:0000024} O15519 CASP8 and FADD-like apoptosis regulator protein 20130413 {GO:0005515=IPI, GO:2001237=IMP, GO:0043066=IMP, GO:0006915=IEA, GO:1901740=ISS, GO:0014732=ISS, GO:0042981=IEA, GO:0043085=IDA, GO:0002020=IPI, GO:0004197=IEA, GO:0005737=IDA, GO:0007519=ISS, GO:0019048=IEA, GO:0006508=IEA, GO:0043403=ISS, GO:0014842=ISS, GO:0043123=IEP, GO:0014866=ISS} apoptotic process, negative regulation of apoptotic process, negative regulation of extrinsic apoptotic signaling pathway, negative regulation of myoblast fusion, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of catalytic activity, proteolysis, regulation of apoptotic process, regulation of satellite cell proliferation, skeletal muscle atrophy, skeletal muscle tissue development, skeletal muscle tissue regeneration, skeletal myofibril assembly, virus-host interaction cytoplasm cysteine-type endopeptidase activity, protease binding, protein binding Human CFP Reactome UniProtKB {GO:0006957=Reactome:REACT_8001, GO:0030449=Reactome:REACT_118707, GO:0006956=Reactome:REACT_8024, GO:0006955=PMID:8530058, GO:0045087=Reactome:REACT_6802, GO:0005576=Reactome:REACT_118641, GO:0005615=PMID:8530058, GO:0042742=PMID:8530058} P27918 Properdin protein 20130301 {GO:0006957=TAS, GO:0030449=TAS, GO:0006956=TAS, GO:0006955=TAS, GO:0045087=TAS, GO:0005576=TAS, GO:0005615=TAS, GO:0042742=TAS} complement activation, complement activation, alternative pathway, defense response to bacterium, immune response, innate immune response, regulation of complement activation extracellular region, extracellular space Human CFTR IntAct UniProtKB {GO:0005515=PMID:22121115, GO:0030321=GO_REF:0000019, GO:0006695=GO_REF:0000019, GO:0043627=GO_REF:0000019, GO:0005886=Reactome:REACT_111162, GO:0030324=GO_REF:0000019, GO:0043434=GO_REF:0000019, GO:0042626=GO_REF:0000002, GO:0030301=GO_REF:0000019, GO:0031205=PMID:9792704, GO:0005254=PMID:22178883, GO:0032870=GO_REF:0000019, GO:0016323=PMID:11707463, GO:0016324=PMID:12801959, GO:0042311=GO_REF:0000019, GO:0045909=GO_REF:0000019, GO:0006810=PMID:7541313, GO:0006833=GO_REF:0000019, GO:0034097=GO_REF:0000019, GO:0016887=GO_REF:0000002, GO:0030659=GO_REF:0000019, GO:0005260=PMID:11707463, GO:0005224=PMID:10581360, GO:0007585=PMID:9875854, GO:0042493=GO_REF:0000019, GO:0034707=GO_REF:0000037, GO:0030165=PMID:11707463, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0019869=PMID:22178883, GO:0043234=PMID:17462998, GO:0005902=GO_REF:0000019, GO:0031901=GO_REF:0000039, GO:0015701=GO_REF:0000019, GO:0016021=GO_REF:0000002, GO:0019899=PMID:19398555, GO:0015705=GO_REF:0000019, GO:0005769=PMID:19398555} P13569 Cystic fibrosis transmembrane conductance regulator protein 20130415 {GO:0005515=IPI, GO:0030321=IEA, GO:0006695=IEA, GO:0043627=IEA, GO:0005886=TAS, GO:0030324=IEA, GO:0043434=IEA, GO:0042626=IEA, GO:0030301=IEA, GO:0031205=IDA, GO:0005254=IDA, GO:0032870=IEA, GO:0016323=NAS, GO:0016324=IDA, GO:0042311=IEA, GO:0045909=IEA, GO:0006810=TAS, GO:0006833=IEA, GO:0034097=IEA, GO:0016887=IEA, GO:0030659=IEA, GO:0005260=NAS, GO:0005224=TAS, GO:0007585=TAS, GO:0042493=IEA, GO:0034707=IEA, GO:0030165=IDA, GO:0055085=TAS, GO:0005524=IEA, GO:0019869=IDA, GO:0043234=IDA, GO:0005902=IEA, GO:0031901=IEA, GO:0015701=IEA, GO:0016021=IEA, GO:0019899=IPI, GO:0015705=IEA, GO:0005769=IDA} bicarbonate transport, cellular response to hormone stimulus, cholesterol biosynthetic process, cholesterol transport, iodide transport, lung development, positive regulation of vasodilation, respiratory gaseous exchange, response to cytokine stimulus, response to drug, response to estrogen stimulus, response to peptide hormone stimulus, transepithelial chloride transport, transmembrane transport, transport, vasodilation, water transport apical plasma membrane, basolateral plasma membrane, chloride channel complex, cytoplasmic vesicle membrane, early endosome, early endosome membrane, endoplasmic reticulum Sec complex, integral to membrane, microvillus, plasma membrane, protein complex ATP binding, ATP-binding and phosphorylation-dependent chloride channel activity, ATPase activity, ATPase activity, coupled to transmembrane movement of substances, PDZ domain binding, channel-conductance-controlling ATPase activity, chloride channel activity, chloride channel inhibitor activity, enzyme binding, protein binding Human UniProtKB:Q96RN1 CGA BHF-UCL UniProtKB {GO:0005515=PMID:15662415, GO:0008406=GO_REF:0000019, GO:0046621=GO_REF:0000019, GO:0008284=PMID:20613903, GO:0030335=PMID:20613903, GO:0007267=PMID:481597, GO:0005576=Reactome:REACT_22268, GO:0030878=GO_REF:0000019, GO:0032870=GO_REF:0000019, GO:0007165=PMID:481597, GO:0048589=GO_REF:0000019, GO:0016486=Reactome:REACT_15452, GO:0046884=GO_REF:0000019, GO:0032275=GO_REF:0000019, GO:0005179=GO_REF:0000037, GO:0006590=GO_REF:0000019, GO:0044267=Reactome:REACT_17015} P01215 Glycoprotein hormones alpha chain protein 20120821 {GO:0005515=IPI, GO:0008406=IEA, GO:0046621=IEA, GO:0008284=NAS, GO:0030335=NAS, GO:0007267=TAS, GO:0005576=TAS, GO:0030878=IEA, GO:0032870=IEA, GO:0007165=TAS, GO:0048589=IEA, GO:0016486=TAS, GO:0046884=IEA, GO:0032275=IEA, GO:0005179=IEA, GO:0006590=IEA, GO:0044267=TAS} cell-cell signaling, cellular protein metabolic process, cellular response to hormone stimulus, developmental growth, follicle-stimulating hormone secretion, gonad development, luteinizing hormone secretion, negative regulation of organ growth, peptide hormone processing, positive regulation of cell migration, positive regulation of cell proliferation, signal transduction, thyroid gland development, thyroid hormone generation extracellular region hormone activity, protein binding Human CGB Reactome UniProtKB {GO:0007165=PMID:10468638, GO:0016486=Reactome:REACT_15452, GO:0005179=GO_REF:0000037, GO:0007267=PMID:6194155, GO:0006915=PMID:7723844, GO:0005576=Reactome:REACT_15432, GO:0007292=PMID:10468638, GO:0044267=Reactome:REACT_17015} P01233 Choriogonadotropin subunit beta protein 20081001 {GO:0007165=TAS, GO:0016486=TAS, GO:0005179=IEA, GO:0007267=TAS, GO:0006915=TAS, GO:0005576=TAS, GO:0007292=TAS, GO:0044267=TAS} apoptotic process, cell-cell signaling, cellular protein metabolic process, female gamete generation, peptide hormone processing, signal transduction extracellular region hormone activity Human CGB5 null null {} null null null null {} null null null CGGBP1 HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0003690=PMID:8626781, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037} Q9UFW8 CGG triplet repeat-binding protein 1 protein 20110516 {GO:0006355=IEA, GO:0003690=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus, nucleus double-stranded DNA binding NOT Human CGN Reactome UniProtKB {GO:0005515=PMID:11042084, GO:0008150=GO_REF:0000015, GO:0043296=GO_REF:0000019, GO:0003774=GO_REF:0000002, GO:0030054=Reactome:REACT_121319, GO:0007179=Reactome:REACT_120726, GO:0003779=GO_REF:0000024, GO:0005923=PMID:22006950, GO:0016459=GO_REF:0000002} Q9P2M7 Cingulin protein 20120223 {GO:0005515=IPI, GO:0008150=ND, GO:0043296=IEA, GO:0003774=IEA, GO:0030054=TAS, GO:0007179=TAS, GO:0003779=ISS, GO:0005923=IDA, GO:0016459=IEA} biological_process, transforming growth factor beta receptor signaling pathway apical junction complex, cell junction, myosin complex, tight junction actin binding, motor activity, protein binding Human CGNL1 UniProtKB UniProtKB {GO:0003774=GO_REF:0000002, GO:0005923=GO_REF:0000039, GO:0016459=GO_REF:0000002} Q0VF96 Cingulin-like protein 1 protein 20130413 {GO:0003774=IEA, GO:0005923=IEA, GO:0016459=IEA} myosin complex, tight junction motor activity Human UniProtKB-SubCell:SL-0265 CGRRF1 PINC UniProtKB {GO:0008285=PMID:8968090, GO:0006950=PMID:8968090, GO:0005634=GO_REF:0000039, GO:0007050=GO_REF:0000037, GO:0008270=GO_REF:0000002} Q99675 Cell growth regulator with RING finger domain protein 1 protein 20030904 {GO:0008285=TAS, GO:0006950=TAS, GO:0005634=IEA, GO:0007050=IEA, GO:0008270=IEA} cell cycle arrest, negative regulation of cell proliferation, response to stress nucleus zinc ion binding Human CH25H Reactome UniProtKB {GO:0006629=PMID:9852097, GO:0005506=GO_REF:0000002, GO:0001567=GO_REF:0000003, GO:0006699=Reactome:REACT_11054, GO:0008395=Reactome:REACT_10030, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_10030, GO:0016126=GO_REF:0000037, GO:0005789=GO_REF:0000039, GO:0006633=GO_REF:0000002, GO:0008206=Reactome:REACT_11040, GO:0016021=GO_REF:0000037, GO:0008203=GO_REF:0000019} O95992 Cholesterol 25-hydroxylase protein 20130213 {GO:0006629=TAS, GO:0005506=IEA, GO:0001567=IEA, GO:0006699=TAS, GO:0008395=TAS, GO:0044281=TAS, GO:0005829=TAS, GO:0016126=IEA, GO:0005789=IEA, GO:0006633=IEA, GO:0008206=TAS, GO:0016021=IEA, GO:0008203=IEA} bile acid biosynthetic process, bile acid metabolic process, cholesterol metabolic process, fatty acid biosynthetic process, lipid metabolic process, small molecule metabolic process, sterol biosynthetic process cytosol, endoplasmic reticulum membrane, integral to membrane cholesterol 25-hydroxylase activity, iron ion binding, steroid hydroxylase activity Human CHAC1 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0006986=GO_REF:0000037, GO:0005802=GO_REF:0000024, GO:0045746=PMID:22445366, GO:0005794=GO_REF:0000039, GO:0007219=GO_REF:0000037, GO:0070059=PMID:19109178, GO:0005112=GO_REF:0000024, GO:0010955=PMID:22445366, GO:0005829=PMID:19109178, GO:0022008=GO_REF:0000024} Q9BUX1 Cation transport regulator-like protein 1 protein 20130415 {GO:0005515=IPI, GO:0006986=IEA, GO:0005802=ISS, GO:0045746=IMP, GO:0005794=IEA, GO:0007219=IEA, GO:0070059=IMP, GO:0005112=ISS, GO:0010955=IMP, GO:0005829=IDA, GO:0022008=ISS} Notch signaling pathway, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, negative regulation of Notch signaling pathway, negative regulation of protein processing, neurogenesis, response to unfolded protein Golgi apparatus, cytosol, trans-Golgi network Notch binding, protein binding Human UniProtKB:Q9BQY4 CHAC2 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q8WUX2 Cation transport regulator-like protein 2 protein 20080507 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human CHAD UniProtKB UniProtKB {GO:0001502=GO_REF:0000019, GO:0005578=GO_REF:0000029, GO:0001558=GO_REF:0000029, GO:0005201=GO_REF:0000029} O15335 Chondroadherin protein 20021106 {GO:0001502=IEA, GO:0005578=TAS, GO:0001558=NAS, GO:0005201=NAS} cartilage condensation, regulation of cell growth proteinaceous extracellular matrix extracellular matrix structural constituent Human CHAF1A BHF-UCL UniProtKB {GO:0005515=PMID:21570500, GO:0006355=GO_REF:0000037, GO:0033186=PMID:8858152, GO:0070087=PMID:15882967, GO:0006335=PMID:7600578, GO:0071778=PMID:12837248, GO:0006351=GO_REF:0000037, GO:0006260=GO_REF:0000037, GO:0007049=GO_REF:0000037, GO:0006281=GO_REF:0000037, GO:0006461=PMID:7600578, GO:0031497=PMID:8858152, GO:0003682=PMID:7600578, GO:0051082=PMID:7600578} Q13111 Chromatin assembly factor 1 subunit A protein 20100127 {GO:0005515=IPI, GO:0006355=IEA, GO:0033186=IDA, GO:0070087=IPI, GO:0006335=TAS, GO:0071778=IDA, GO:0006351=IEA, GO:0006260=IEA, GO:0007049=IEA, GO:0006281=IEA, GO:0006461=TAS, GO:0031497=IDA, GO:0003682=TAS, GO:0051082=TAS} DNA repair, DNA replication, DNA replication-dependent nucleosome assembly, cell cycle, chromatin assembly, protein complex assembly, regulation of transcription, DNA-dependent, transcription, DNA-dependent CAF-1 complex, WINAC complex chromatin binding, chromo shadow domain binding, protein binding, unfolded protein binding Human UniProtKB:P45973 CHAF1B HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0033186=PMID:8858152, GO:0005730=GO_REF:0000052, GO:0006335=PMID:7600578, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037, GO:0005829=PMID:16780588, GO:0006260=GO_REF:0000037, GO:0042393=PMID:7600578, GO:0007049=GO_REF:0000037, GO:0005737=PMID:9614144, GO:0006461=PMID:7600578, GO:0006281=GO_REF:0000037, GO:0031497=PMID:8858152, GO:0003682=PMID:7600578, GO:0005654=PMID:16780588, GO:0051082=PMID:7600578} Q13112 Chromatin assembly factor 1 subunit B protein 20111111 {GO:0006355=IEA, GO:0033186=IDA, GO:0005730=IDA, GO:0006335=TAS, GO:0005634=IDA, GO:0006351=IEA, GO:0005829=IDA, GO:0006260=IEA, GO:0042393=NAS, GO:0007049=IEA, GO:0005737=NAS, GO:0006461=TAS, GO:0006281=IEA, GO:0031497=IDA, GO:0003682=TAS, GO:0005654=IDA, GO:0051082=TAS} DNA repair, DNA replication, DNA replication-dependent nucleosome assembly, cell cycle, chromatin assembly, protein complex assembly, regulation of transcription, DNA-dependent, transcription, DNA-dependent CAF-1 complex, cytoplasm, cytosol, nucleolus, nucleoplasm, nucleus chromatin binding, histone binding, unfolded protein binding NOT Human CHAMP1 HPA UniProtKB {GO:0005515=PMID:21063390, GO:0000793=PMID:21063390, GO:0034501=PMID:21063390, GO:0005819=PMID:21063390, GO:0005730=GO_REF:0000052, GO:0035372=PMID:21063390, GO:0005634=GO_REF:0000052, GO:0031134=PMID:21063390, GO:0003676=GO_REF:0000002, GO:0005737=GO_REF:0000037, GO:0051315=PMID:21063390, GO:0000777=PMID:21063390, GO:0008270=GO_REF:0000002} Q96JM3 Chromosome alignment-maintaining phosphoprotein 1 protein 20101115 {GO:0005515=IPI, GO:0000793=IDA, GO:0034501=IMP, GO:0005819=IDA, GO:0005730=IDA, GO:0035372=IMP, GO:0005634=IDA, GO:0031134=IMP, GO:0003676=IEA, GO:0005737=IEA, GO:0051315=IMP, GO:0000777=IDA, GO:0008270=IEA} attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation, protein localization to kinetochore, protein localization to microtubule, sister chromatid biorientation condensed chromosome, condensed chromosome kinetochore, cytoplasm, nucleolus, nucleus, spindle nucleic acid binding, protein binding, zinc ion binding NOT Human CHAT Reactome UniProtKB {GO:0030424=GO_REF:0000019, GO:0016746=GO_REF:0000038, GO:0004102=GO_REF:0000003, GO:0043179=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0005634=PMID:10861222, GO:0044281=Reactome:REACT_111217, GO:0007274=GO_REF:0000019, GO:0007269=Reactome:REACT_13723, GO:0016358=GO_REF:0000019, GO:0005829=Reactome:REACT_15484, GO:0005739=GO_REF:0000019, GO:0005737=PMID:10861222, GO:0007529=GO_REF:0000019, GO:0007628=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0007622=GO_REF:0000019, GO:0042136=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0046474=Reactome:REACT_121401, GO:0006656=Reactome:REACT_121238} P28329 Choline O-acetyltransferase protein 20130301 {GO:0030424=IEA, GO:0016746=IEA, GO:0004102=IEA, GO:0043179=IEA, GO:0007268=TAS, GO:0005634=TAS, GO:0044281=TAS, GO:0007274=IEA, GO:0007269=TAS, GO:0016358=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0005737=TAS, GO:0007529=IEA, GO:0007628=IEA, GO:0043025=IEA, GO:0007622=IEA, GO:0042136=IEA, GO:0006644=TAS, GO:0046474=TAS, GO:0006656=TAS} adult walking behavior, dendrite development, establishment of synaptic specificity at neuromuscular junction, glycerophospholipid biosynthetic process, neuromuscular synaptic transmission, neurotransmitter biosynthetic process, neurotransmitter secretion, phosphatidylcholine biosynthetic process, phospholipid metabolic process, rhythmic behavior, rhythmic excitation, small molecule metabolic process, synaptic transmission axon, cytoplasm, cytosol, mitochondrion, neuronal cell body, nucleus choline O-acetyltransferase activity, transferase activity, transferring acyl groups Human CHCHD1 HPA UniProtKB {GO:0005515=PMID:22190034, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q96BP2 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 protein 20111111 {GO:0005515=IPI, GO:0005739=IDA, GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA} cytoplasm, mitochondrion, nucleolus, nucleus protein binding Human CHCHD2 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039} Q9Y6H1 Coiled-coil-helix-coiled-coil-helix domain-containing protein 2, mitochondrial protein 20130413 {GO:0005739=IEA} mitochondrion Human UniProtKB-SubCell:SL-0173 CHCHD3 HPA UniProtKB {GO:0005515=PMID:19389623, GO:0005739=GO_REF:0000052, GO:0005737=PMID:22567091, GO:0032947=GO_REF:0000024, GO:0008053=PMID:21081504, GO:0019902=PMID:19389623, GO:0005743=GO_REF:0000024, GO:0007007=PMID:21081504, GO:0005634=PMID:22567091, GO:0000122=PMID:22567091, GO:0001227=PMID:22567091} Q9NX63 Coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial protein 20111111 {GO:0005515=IPI, GO:0005739=IDA, GO:0005737=IDA, GO:0032947=ISS, GO:0008053=IMP, GO:0019902=IDA, GO:0005743=ISS, GO:0007007=IMP, GO:0005634=IDA, GO:0000122=IDA, GO:0001227=IDA} inner mitochondrial membrane organization, mitochondrial fusion, negative regulation of transcription from RNA polymerase II promoter cytoplasm, mitochondrial inner membrane, mitochondrion, nucleus RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, phosphatase binding, protein binding, protein complex scaffold Human CHCHD4 Reactome UniProtKB {GO:0005758=PMID:16185709, GO:0006626=Reactome:REACT_118595, GO:0015035=PMID:19182799, GO:0051084=PMID:21059946, GO:0044267=Reactome:REACT_17015, GO:0045041=PMID:16185709, GO:0022417=PMID:21059946} Q8N4Q1 Mitochondrial intermembrane space import and assembly protein 40 protein 20110427 {GO:0005758=IDA, GO:0006626=TAS, GO:0015035=IMP, GO:0051084=IMP, GO:0044267=TAS, GO:0045041=IMP, GO:0022417=IMP} 'de novo' posttranslational protein folding, cellular protein metabolic process, protein import into mitochondrial intermembrane space, protein maturation by protein folding, protein targeting to mitochondrion mitochondrial intermembrane space protein disulfide oxidoreductase activity Human CHCHD6 UniProtKB UniProtKB {GO:0005739=PMID:22228767, GO:0005515=PMID:22228767, GO:0005743=PMID:22228767, GO:0042407=PMID:22228767, GO:0006974=PMID:22228767} Q9BRQ6 Coiled-coil-helix-coiled-coil-helix domain-containing protein 6, mitochondrial protein 20120228 {GO:0005739=IMP, GO:0005515=IPI, GO:0005743=IDA, GO:0042407=IMP, GO:0006974=IDA} cristae formation, response to DNA damage stimulus mitochondrial inner membrane, mitochondrion protein binding Human UniProtKB:Q9NRI5 CHD1 PINC UniProtKB {GO:0005737=GO_REF:0000039, GO:0004003=PMID:9326634, GO:0006357=PMID:9326634, GO:0005634=GO_REF:0000039, GO:0006338=GO_REF:0000019, GO:0035064=PMID:21029866, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O14646 Chromodomain-helicase-DNA-binding protein 1 protein 20030904 {GO:0005737=IEA, GO:0004003=TAS, GO:0006357=TAS, GO:0005634=IEA, GO:0006338=IEA, GO:0035064=IDA, GO:0005524=IEA, GO:0003677=IEA, GO:0006351=IEA} chromatin remodeling, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, nucleus ATP binding, ATP-dependent DNA helicase activity, DNA binding, methylated histone residue binding Human CHD1L HPA UniProtKB {GO:0005515=PMID:19661379, GO:0006200=PMID:19661379, GO:0005886=GO_REF:0000052, GO:0004386=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000002, GO:0006974=PMID:19661379, GO:0005737=GO_REF:0000052, GO:0004003=PMID:19661379, GO:0006281=PMID:19661379, GO:0000166=PMID:19661379, GO:0006338=PMID:19661379, GO:0016887=PMID:19661379} Q86WJ1 Chromodomain-helicase-DNA-binding protein 1-like protein 20101115 {GO:0005515=IPI, GO:0006200=IMP, GO:0005886=IDA, GO:0004386=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0005524=IEA, GO:0003677=IEA, GO:0006974=IDA, GO:0005737=IDA, GO:0004003=TAS, GO:0006281=TAS, GO:0000166=IDA, GO:0006338=IDA, GO:0016887=IMP} ATP catabolic process, DNA repair, chromatin remodeling, response to DNA damage stimulus cytoplasm, nucleolus, nucleus, plasma membrane ATP binding, ATP-dependent DNA helicase activity, ATPase activity, DNA binding, helicase activity, nucleic acid binding, nucleotide binding, protein binding Human CHD2 PINC UniProtKB {GO:0004003=PMID:9326634, GO:0006357=PMID:9326634, GO:0004386=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000037} O14647 Chromodomain-helicase-DNA-binding protein 2 protein 20030904 {GO:0004003=TAS, GO:0006357=TAS, GO:0004386=IEA, GO:0005634=IEA, GO:0003676=IEA, GO:0005524=IEA, GO:0003677=IEA} regulation of transcription from RNA polymerase II promoter nucleus ATP binding, ATP-dependent DNA helicase activity, DNA binding, helicase activity, nucleic acid binding Human CHD3 HPA UniProtKB {GO:0005515=PMID:20676135, GO:0008026=GO_REF:0000002, GO:0005813=PMID:17626165, GO:0006355=PMID:9688266, GO:0006357=PMID:9326634, GO:0004386=PMID:9688266, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0016818=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0006333=GO_REF:0000019, GO:0051297=PMID:17626165, GO:0005737=PMID:17626165, GO:0004003=PMID:9326634, GO:0016581=PMID:17827154, GO:0008270=PMID:9688266, GO:0007051=PMID:17626165, GO:0045111=GO_REF:0000052, GO:0016568=GO_REF:0000037} Q12873 Chromodomain-helicase-DNA-binding protein 3 protein 20120912 {GO:0005515=IPI, GO:0008026=IEA, GO:0005813=IDA, GO:0006355=NAS, GO:0006357=TAS, GO:0004386=NAS, GO:0005730=IDA, GO:0005634=IDA, GO:0016818=IEA, GO:0003677=IEA, GO:0005524=IEA, GO:0006351=IEA, GO:0006333=IEA, GO:0051297=IDA, GO:0005737=IDA, GO:0004003=TAS, GO:0016581=IDA, GO:0008270=NAS, GO:0007051=IDA, GO:0045111=IDA, GO:0016568=IEA} centrosome organization, chromatin assembly or disassembly, chromatin modification, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, spindle organization, transcription, DNA-dependent NuRD complex, centrosome, cytoplasm, intermediate filament cytoskeleton, nucleolus, nucleus ATP binding, ATP-dependent DNA helicase activity, ATP-dependent helicase activity, DNA binding, helicase activity, hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, protein binding, zinc ion binding Human CHD4 HPA UniProtKB {GO:0001103=PMID:22926524, GO:0008026=GO_REF:0000002, GO:0005515=PMID:17314511, GO:0005813=PMID:17626165, GO:0006355=GO_REF:0000002, GO:0006357=PMID:9326634, GO:0005634=GO_REF:0000052, GO:0016818=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0005737=PMID:17626165, GO:0004003=PMID:9326634, GO:0016581=PMID:19644445, GO:0008270=GO_REF:0000002, GO:0008134=GO_REF:0000019, GO:0016568=GO_REF:0000037} Q14839 Chromodomain-helicase-DNA-binding protein 4 protein 20111111 {GO:0001103=IPI, GO:0008026=IEA, GO:0005515=IPI, GO:0005813=IDA, GO:0006355=IEA, GO:0006357=TAS, GO:0005634=IDA, GO:0016818=IEA, GO:0003677=IEA, GO:0005524=IEA, GO:0006351=IEA, GO:0005737=IDA, GO:0004003=TAS, GO:0016581=IDA, GO:0008270=IEA, GO:0008134=IEA, GO:0016568=IEA} chromatin modification, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription, DNA-dependent NuRD complex, centrosome, cytoplasm, nucleus ATP binding, ATP-dependent DNA helicase activity, ATP-dependent helicase activity, DNA binding, RNA polymerase II repressing transcription factor binding, hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, protein binding, transcription factor binding, zinc ion binding Human CHD5 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0004386=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0016818=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q8TDI0 Chromodomain-helicase-DNA-binding protein 5 protein 20130413 {GO:0008026=IEA, GO:0006355=IEA, GO:0004386=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0016818=IEA, GO:0003676=IEA, GO:0005524=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0016568=IEA} chromatin modification, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus ATP binding, ATP-dependent helicase activity, DNA binding, helicase activity, hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 CHD6 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0006355=PMID:12592387, GO:0003682=PMID:12592387, GO:0006338=PMID:12592387, GO:0005634=PMID:12592387, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0007399=PMID:12592387} Q8TD26 Chromodomain-helicase-DNA-binding protein 6 protein 20030424 {GO:0008026=IEA, GO:0006355=NAS, GO:0003682=NAS, GO:0006338=NAS, GO:0005634=NAS, GO:0005524=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0007399=NAS} chromatin remodeling, nervous system development, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus ATP binding, ATP-dependent helicase activity, DNA binding, chromatin binding Human CHD7 BHF-UCL UniProtKB {GO:0060123=PMID:9556299, GO:0005515=PMID:20453063, GO:0016817=GO_REF:0000002, GO:0060041=PMID:15300250, GO:0008015=GO_REF:0000019, GO:0007605=GO_REF:0000019, GO:0048844=GO_REF:0000019, GO:0005634=PMID:17299439, GO:0048752=GO_REF:0000019, GO:0007512=GO_REF:0000019, GO:0007628=GO_REF:0000019, GO:0060021=PMID:15300250, GO:0043010=GO_REF:0000019, GO:0040018=GO_REF:0000019, GO:0048806=PMID:15300250, GO:0006355=PMID:17937444, GO:0042472=PMID:15300250, GO:0021545=PMID:9556299, GO:0004386=GO_REF:0000037, GO:0007417=PMID:9556299, GO:0001701=PMID:15300250, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0001501=PMID:16155193, GO:0003007=PMID:15300250, GO:0030217=PMID:17684005, GO:0050890=PMID:16155193, GO:0003682=PMID:17299439, GO:0060324=PMID:15300250, GO:0035116=GO_REF:0000019, GO:0060173=PMID:17937444, GO:0030540=GO_REF:0000019, GO:0043584=PMID:15300250, GO:0016568=GO_REF:0000037} Q9P2D1 Chromodomain-helicase-DNA-binding protein 7 protein 20080923 {GO:0060123=IMP, GO:0005515=IPI, GO:0016817=IEA, GO:0060041=IMP, GO:0008015=IEA, GO:0007605=IEA, GO:0048844=IEA, GO:0005634=TAS, GO:0048752=IEA, GO:0007512=IEA, GO:0007628=IEA, GO:0060021=IMP, GO:0043010=IEA, GO:0040018=IEA, GO:0048806=IMP, GO:0006355=NAS, GO:0042472=IMP, GO:0021545=IMP, GO:0004386=IEA, GO:0007417=IMP, GO:0001701=IMP, GO:0003677=IEA, GO:0005524=IEA, GO:0006351=IEA, GO:0001501=IMP, GO:0003007=IMP, GO:0030217=IMP, GO:0050890=IMP, GO:0003682=TAS, GO:0060324=IMP, GO:0035116=IEA, GO:0060173=IMP, GO:0030540=IEA, GO:0043584=IMP, GO:0016568=IEA} T cell differentiation, adult heart development, adult walking behavior, artery morphogenesis, blood circulation, camera-type eye development, central nervous system development, chromatin modification, cognition, cranial nerve development, embryonic hindlimb morphogenesis, face development, female genitalia development, genitalia development, heart morphogenesis, in utero embryonic development, inner ear morphogenesis, limb development, nose development, palate development, positive regulation of multicellular organism growth, regulation of growth hormone secretion, regulation of transcription, DNA-dependent, retina development in camera-type eye, semicircular canal morphogenesis, sensory perception of sound, skeletal system development, transcription, DNA-dependent nucleus ATP binding, DNA binding, chromatin binding, helicase activity, hydrolase activity, acting on acid anhydrides, protein binding Human CHD8 GOC UniProtKB {GO:0005515=PMID:20453063, GO:0008013=PMID:18378692, GO:0030178=PMID:18378692, GO:0005634=PMID:20453063, GO:0035064=PMID:17938208, GO:0042393=GO_REF:0000024, GO:0002039=GO_REF:0000024, GO:0045944=PMID:17938208, GO:0071339=PMID:15960975, GO:0045945=PMID:17938208, GO:0032508=PMID:18378692, GO:0060070=PMID:18378692, GO:0008094=PMID:18378692, GO:0043066=GO_REF:0000019, GO:0043044=PMID:18378692, GO:0004386=GO_REF:0000002, GO:0001701=GO_REF:0000019, GO:0005524=PMID:18378692, GO:0003677=PMID:18378692, GO:0003678=PMID:18378692, GO:0006351=GO_REF:0000037, GO:0043234=PMID:18378692, GO:0045893=PMID:17938208, GO:0045892=PMID:18378692, GO:0070016=GO_REF:0000019} Q9HCK8 Chromodomain-helicase-DNA-binding protein 8 protein 20130413 {GO:0005515=IPI, GO:0008013=IDA, GO:0030178=IDA, GO:0005634=IDA, GO:0035064=IDA, GO:0042393=ISS, GO:0002039=ISS, GO:0045944=IMP, GO:0071339=IDA, GO:0045945=IMP, GO:0032508=IMP, GO:0060070=IDA, GO:0008094=IDA, GO:0043066=IEA, GO:0043044=IMP, GO:0004386=IEA, GO:0001701=IEA, GO:0005524=IDA, GO:0003677=IMP, GO:0003678=IMP, GO:0006351=IEA, GO:0043234=IDA, GO:0045893=IDA, GO:0045892=IMP, GO:0070016=IEA} ATP-dependent chromatin remodeling, DNA duplex unwinding, canonical Wnt receptor signaling pathway, in utero embryonic development, negative regulation of Wnt receptor signaling pathway, negative regulation of apoptotic process, negative regulation of transcription, DNA-dependent, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase III promoter, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent MLL1 complex, nucleus, protein complex ATP binding, DNA binding, DNA helicase activity, DNA-dependent ATPase activity, armadillo repeat domain binding, beta-catenin binding, helicase activity, histone binding, methylated histone residue binding, p53 binding, protein binding Human CHD9 Reactome UniProtKB {GO:0005737=GO_REF:0000039, GO:0006355=GO_REF:0000037, GO:0016817=GO_REF:0000002, GO:0004386=GO_REF:0000037, GO:0005654=Reactome:REACT_19175, GO:0005634=GO_REF:0000038, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0044255=Reactome:REACT_22279, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q3L8U1 Chromodomain-helicase-DNA-binding protein 9 protein 20130301 {GO:0005737=IEA, GO:0006355=IEA, GO:0016817=IEA, GO:0004386=IEA, GO:0005654=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0005524=IEA, GO:0003677=IEA, GO:0044255=TAS, GO:0006351=IEA, GO:0016568=IEA} cellular lipid metabolic process, chromatin modification, regulation of transcription, DNA-dependent, small molecule metabolic process, transcription, DNA-dependent cytoplasm, nucleoplasm, nucleus ATP binding, DNA binding, helicase activity, hydrolase activity, acting on acid anhydrides Human CHDH UniPathway UniProtKB {GO:0050660=GO_REF:0000002, GO:0019285=GO_REF:0000041, GO:0005743=GO_REF:0000039, GO:0008812=GO_REF:0000003} Q8NE62 Choline dehydrogenase, mitochondrial protein 20130413 {GO:0050660=IEA, GO:0019285=IEA, GO:0005743=IEA, GO:0008812=IEA} glycine betaine biosynthetic process from choline mitochondrial inner membrane choline dehydrogenase activity, flavin adenine dinucleotide binding Human UniPathway:UPA00529 CHEK1 GOC UniProtKB {GO:0005515=PMID:22939624, GO:0033261=GO_REF:0000019, GO:0005657=GO_REF:0000019, GO:0031572=PMID:20932473, GO:0005634=PMID:15311285, GO:0010569=PMID:15665856, GO:0005829=Reactome:REACT_111221, GO:0042127=GO_REF:0000019, GO:0000086=GO_REF:0000019, GO:0018107=PMID:15665856, GO:0010767=GO_REF:0000024, GO:2000615=GO_REF:0000024, GO:0000785=GO_REF:0000024, GO:0000781=PMID:15149599, GO:0005813=PMID:15311285, GO:0000794=PMID:9382850, GO:0046602=PMID:15311285, GO:0071313=GO_REF:0000019, GO:0035407=PMID:18243098, GO:0005524=GO_REF:0000037, GO:0035402=PMID:18243098, GO:0006974=PMID:20932473, GO:0006975=PMID:16963448, GO:0006260=Reactome:REACT_6769, GO:0045839=PMID:15311285, GO:0006281=PMID:19716789, GO:0004674=PMID:16963448, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_6869, GO:0000077=PMID:16963448, GO:0090399=PMID:15149599, GO:0071260=PMID:19593445, GO:0048096=GO_REF:0000024} O14757 Serine/threonine-protein kinase Chk1 protein 20130413 {GO:0005515=IPI, GO:0033261=IEA, GO:0005657=IEA, GO:0031572=IMP, GO:0005634=IDA, GO:0010569=IDA, GO:0005829=TAS, GO:0042127=IEA, GO:0000086=IEA, GO:0018107=IDA, GO:0010767=ISS, GO:2000615=ISS, GO:0000785=ISS, GO:0000781=IDA, GO:0005813=IDA, GO:0000794=IDA, GO:0046602=IDA, GO:0071313=IEA, GO:0035407=IDA, GO:0005524=IEA, GO:0035402=IDA, GO:0006974=IMP, GO:0006975=IDA, GO:0006260=TAS, GO:0045839=IDA, GO:0006281=IMP, GO:0004674=IDA, GO:0000075=TAS, GO:0005654=TAS, GO:0000077=IDA, GO:0090399=NAS, GO:0071260=IEP, GO:0048096=ISS} DNA damage checkpoint, DNA damage induced protein phosphorylation, DNA repair, DNA replication, G2 DNA damage checkpoint, G2/M transition of mitotic cell cycle, cell cycle checkpoint, cellular response to caffeine, cellular response to mechanical stimulus, chromatin-mediated maintenance of transcription, histone H3-T11 phosphorylation, negative regulation of mitosis, peptidyl-threonine phosphorylation, regulation of S phase, regulation of cell proliferation, regulation of double-strand break repair via homologous recombination, regulation of histone H3-K9 acetylation, regulation of mitotic centrosome separation, regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage, replicative senescence, response to DNA damage stimulus centrosome, chromatin, chromosome, telomeric region, condensed nuclear chromosome, cytosol, nucleoplasm, nucleus, replication fork ATP binding, histone kinase activity (H3-T11 specific), protein binding, protein serine/threonine kinase activity Human CHEK2 BHF-UCL UniProtKB {GO:0005515=PMID:17525332, GO:0046872=GO_REF:0000037, GO:0042803=PMID:16794575, GO:0006302=PMID:18317453, GO:0046777=PMID:18644861, GO:0000086=PMID:16481012, GO:0090307=PMID:20364141, GO:0044257=PMID:11298456, GO:0010332=GO_REF:0000019, GO:0031625=PMID:22266820, GO:0016772=GO_REF:0000002, GO:0072428=PMID:11298456, GO:0000781=PMID:15149599, GO:0006355=PMID:12717439, GO:0008630=PMID:12717439, GO:0019901=PMID:16481012, GO:0042176=PMID:17101782, GO:0006915=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0006974=PMID:16481012, GO:0006351=GO_REF:0000037, GO:0006975=PMID:11298456, GO:0042770=PMID:14744935, GO:0004672=GO_REF:0000002, GO:0004674=PMID:16794575, GO:0016605=PMID:12402044, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_1603, GO:0000077=PMID:10617473, GO:0090399=PMID:15149599, GO:0045893=PMID:17101782, GO:0051301=GO_REF:0000037} O96017 Serine/threonine-protein kinase Chk2 protein 20110110 {GO:0005515=IPI, GO:0046872=IEA, GO:0042803=IDA, GO:0006302=IMP, GO:0046777=IDA, GO:0000086=IMP, GO:0090307=IMP, GO:0044257=IMP, GO:0010332=IEA, GO:0031625=IPI, GO:0016772=IEA, GO:0072428=IMP, GO:0000781=IDA, GO:0006355=IDA, GO:0008630=IMP, GO:0019901=IPI, GO:0042176=IMP, GO:0006915=IEA, GO:0005524=IEA, GO:0006974=IMP, GO:0006351=IEA, GO:0006975=IMP, GO:0042770=IDA, GO:0004672=IEA, GO:0004674=IDA, GO:0016605=IDA, GO:0000075=TAS, GO:0005654=TAS, GO:0000077=TAS, GO:0090399=NAS, GO:0045893=IDA, GO:0051301=IEA} DNA damage checkpoint, DNA damage induced protein phosphorylation, G2/M transition of mitotic cell cycle, apoptotic process, cell cycle checkpoint, cell division, cellular protein catabolic process, double-strand break repair, intrinsic apoptotic signaling pathway in response to DNA damage, positive regulation of transcription, DNA-dependent, protein autophosphorylation, regulation of protein catabolic process, regulation of transcription, DNA-dependent, replicative senescence, response to DNA damage stimulus, response to gamma radiation, signal transduction in response to DNA damage, signal transduction involved in intra-S DNA damage checkpoint, spindle assembly involved in mitosis, transcription, DNA-dependent PML body, chromosome, telomeric region, nucleoplasm ATP binding, metal ion binding, protein binding, protein homodimerization activity, protein kinase activity, protein kinase binding, protein serine/threonine kinase activity, transferase activity, transferring phosphorus-containing groups, ubiquitin protein ligase binding Human CHERP MGI UniProtKB {GO:0006396=GO_REF:0000002, GO:0048471=PMID:12656674, GO:0005737=PMID:10794731, GO:0008285=PMID:10794731, GO:0051209=PMID:12656674, GO:0003723=GO_REF:0000002, GO:0006874=PMID:10794731, GO:0033017=GO_REF:0000024, GO:0051533=PMID:12656674, GO:0007399=PMID:8896557, GO:0044325=PMID:21454501} Q8IWX8 Calcium homeostasis endoplasmic reticulum protein protein 20091110 {GO:0006396=IEA, GO:0048471=IDA, GO:0005737=IDA, GO:0008285=IDA, GO:0051209=IMP, GO:0003723=IEA, GO:0006874=IDA, GO:0033017=ISS, GO:0051533=IMP, GO:0007399=TAS, GO:0044325=IPI} RNA processing, cellular calcium ion homeostasis, negative regulation of cell proliferation, nervous system development, positive regulation of NFAT protein import into nucleus, release of sequestered calcium ion into cytosol cytoplasm, perinuclear region of cytoplasm, sarcoplasmic reticulum membrane RNA binding, ion channel binding Human CHFR UniProtKB UniProtKB {GO:0000209=PMID:19182791, GO:0005515=PMID:19182791, GO:0006511=GO_REF:0000019, GO:0004842=PMID:19182791, GO:0007093=PMID:19182791, GO:0005634=PMID:18172500, GO:0007067=GO_REF:0000037, GO:0000166=PMID:18172500, GO:0016605=PMID:15467728, GO:0019941=PMID:19182791, GO:0008270=GO_REF:0000002, GO:0000278=GO_REF:0000019, GO:0051301=GO_REF:0000037} Q96EP1 E3 ubiquitin-protein ligase CHFR protein 20090814 {GO:0000209=IDA, GO:0005515=IPI, GO:0006511=IEA, GO:0004842=IDA, GO:0007093=IMP, GO:0005634=IDA, GO:0007067=IEA, GO:0000166=IDA, GO:0016605=IDA, GO:0019941=IDA, GO:0008270=IEA, GO:0000278=IEA, GO:0051301=IEA} cell division, mitosis, mitotic cell cycle, mitotic cell cycle checkpoint, modification-dependent protein catabolic process, protein polyubiquitination, ubiquitin-dependent protein catabolic process PML body, nucleus nucleotide binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human CHGA PINC UniProtKB {GO:0008217=PMID:8406464, GO:0005576=GO_REF:0000039, GO:0030141=GO_REF:0000002, GO:0030658=GO_REF:0000039} P10645 Chromogranin-A protein 20030904 {GO:0008217=TAS, GO:0005576=IEA, GO:0030141=IEA, GO:0030658=IEA} regulation of blood pressure extracellular region, secretory granule, transport vesicle membrane Human CHGB IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0005179=PMID:3608978, GO:0005576=GO_REF:0000039, GO:0030141=GO_REF:0000019} P05060 Secretogranin-1 protein 20130415 {GO:0005515=IPI, GO:0005179=TAS, GO:0005576=IEA, GO:0030141=IEA} extracellular region, secretory granule hormone activity, protein binding Human UniProtKB:Q15796 CHI3L1 UniProtKB UniProtKB {GO:0051897=PMID:21385870, GO:0006032=GO_REF:0000002, GO:0010800=GO_REF:0000024, GO:0007250=GO_REF:0000024, GO:0030324=PMID:18403759, GO:0005975=GO_REF:0000002, GO:0005783=GO_REF:0000024, GO:0051216=PMID:8245017, GO:0005578=PMID:8245017, GO:0045766=PMID:21385870, GO:0004553=GO_REF:0000002, GO:0009612=PMID:20650887, GO:0008061=PMID:12775711, GO:0005737=GO_REF:0000024, GO:0006954=PMID:16234240, GO:0071356=GO_REF:0000024, GO:0070741=PMID:21478032, GO:0034612=PMID:16234240, GO:0070374=PMID:21385870, GO:0070555=PMID:16234240, GO:0004568=PMID:9492324, GO:0072606=GO_REF:0000024, GO:0005201=PMID:8245017} P36222 Chitinase-3-like protein 1 protein 20111221 {GO:0051897=IMP, GO:0006032=IEA, GO:0010800=ISS, GO:0007250=ISS, GO:0030324=IMP, GO:0005975=IEA, GO:0005783=ISS, GO:0051216=NAS, GO:0005578=NAS, GO:0045766=IMP, GO:0004553=IEA, GO:0009612=IEP, GO:0008061=IDA, GO:0005737=ISS, GO:0006954=IEP, GO:0071356=ISS, GO:0070741=IEP, GO:0034612=IEP, GO:0070374=IMP, GO:0070555=IEP, GO:0004568=IDA, GO:0072606=ISS, GO:0005201=NAS} activation of NF-kappaB-inducing kinase activity, carbohydrate metabolic process, cartilage development, cellular response to tumor necrosis factor, chitin catabolic process, inflammatory response, interleukin-8 secretion, lung development, positive regulation of ERK1 and ERK2 cascade, positive regulation of angiogenesis, positive regulation of peptidyl-threonine phosphorylation, positive regulation of protein kinase B signaling cascade, response to interleukin-1, response to interleukin-6, response to mechanical stimulus, response to tumor necrosis factor cytoplasm, endoplasmic reticulum, proteinaceous extracellular matrix chitin binding, chitinase activity, extracellular matrix structural constituent, hydrolase activity, hydrolyzing O-glycosyl compounds Human CHI3L2 PINC UniProtKB {GO:0008061=PMID:22742450, GO:0006032=GO_REF:0000002, GO:0005975=GO_REF:0000002, GO:0005615=PMID:8702629, GO:0004553=GO_REF:0000002, GO:0004568=PMID:22742450} Q15782 Chitinase-3-like protein 2 protein 20030904 {GO:0008061=IDA, GO:0006032=IEA, GO:0005975=IEA, GO:0005615=TAS, GO:0004553=IEA, GO:0004568=IDA} carbohydrate metabolic process, chitin catabolic process extracellular space chitin binding, chitinase activity, hydrolase activity, hydrolyzing O-glycosyl compounds Human CHIC1 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016023=GO_REF:0000039} Q5VXU3 Cysteine-rich hydrophobic domain 1 protein protein 20130413 {GO:0005886=IEA, GO:0016023=IEA} cytoplasmic membrane-bounded vesicle, plasma membrane Human UniProtKB-SubCell:SL-0088 CHIC2 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005886=GO_REF:0000039, GO:0005798=GO_REF:0000019, GO:0005575=GO_REF:0000015} Q9UKJ5 Cysteine-rich hydrophobic domain 2 protein protein 20130415 {GO:0005515=IPI, GO:0003674=ND, GO:0008150=ND, GO:0005886=IEA, GO:0005798=IEA, GO:0005575=ND} biological_process Golgi-associated vesicle, cellular_component, plasma membrane molecular_function, protein binding Human UniProtKB:Q9H8W4 CHID1 UniProtKB UniProtKB {GO:0006032=GO_REF:0000002, GO:0005975=GO_REF:0000002, GO:0045087=GO_REF:0000037, GO:0005576=GO_REF:0000039, GO:0003824=GO_REF:0000002, GO:0005764=GO_REF:0000039, GO:0004568=GO_REF:0000002} Q9BWS9 Chitinase domain-containing protein 1 protein 20130413 {GO:0006032=IEA, GO:0005975=IEA, GO:0045087=IEA, GO:0005576=IEA, GO:0003824=IEA, GO:0005764=IEA, GO:0004568=IEA} carbohydrate metabolic process, chitin catabolic process, innate immune response extracellular region, lysosome catalytic activity, chitinase activity Human UniProtKB-SubCell:SL-0158 CHKA GOC UniProtKB {GO:0006629=PMID:10363580, GO:0033265=GO_REF:0000019, GO:0004305=PMID:19915674, GO:0006646=Reactome:REACT_120919, GO:0004104=GO_REF:0000019, GO:0004103=PMID:19915674, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000019, GO:0019695=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0005829=Reactome:REACT_121281, GO:0007165=PMID:10363580, GO:0016301=GO_REF:0000002, GO:0008144=PMID:19915674, GO:0006869=PMID:10363580, GO:0004871=PMID:10363580, GO:0006657=PMID:19915674, GO:0006644=Reactome:REACT_120870, GO:0046474=Reactome:REACT_121401, GO:0006656=Reactome:REACT_121238} P35790 Choline kinase alpha protein 20130413 {GO:0006629=TAS, GO:0033265=IEA, GO:0004305=IDA, GO:0006646=TAS, GO:0004104=IEA, GO:0004103=IDA, GO:0044281=TAS, GO:0005524=IEA, GO:0019695=IEA, GO:0042803=IEA, GO:0005829=TAS, GO:0007165=TAS, GO:0016301=IEA, GO:0008144=IDA, GO:0006869=TAS, GO:0004871=TAS, GO:0006657=IDA, GO:0006644=TAS, GO:0046474=TAS, GO:0006656=TAS} CDP-choline pathway, choline metabolic process, glycerophospholipid biosynthetic process, lipid metabolic process, lipid transport, phosphatidylcholine biosynthetic process, phosphatidylethanolamine biosynthetic process, phospholipid metabolic process, signal transduction, small molecule metabolic process cytosol ATP binding, choline binding, choline kinase activity, cholinesterase activity, drug binding, ethanolamine kinase activity, kinase activity, protein homodimerization activity, signal transducer activity Human CHKB HPA UniProtKB {GO:0004305=PMID:19915674, GO:0006646=Reactome:REACT_120919, GO:0005737=GO_REF:0000052, GO:0004103=PMID:19915674, GO:0044281=Reactome:REACT_111217, GO:0006657=PMID:19915674, GO:0006644=Reactome:REACT_120870, GO:0005524=GO_REF:0000037, GO:0046474=Reactome:REACT_121401, GO:0006656=Reactome:REACT_121238, GO:0005829=Reactome:REACT_121281} Q9Y259 Choline/ethanolamine kinase protein 20090616 {GO:0004305=IDA, GO:0006646=TAS, GO:0005737=IDA, GO:0004103=IDA, GO:0044281=TAS, GO:0006657=IDA, GO:0006644=TAS, GO:0005524=IEA, GO:0046474=TAS, GO:0006656=TAS, GO:0005829=TAS} CDP-choline pathway, glycerophospholipid biosynthetic process, phosphatidylcholine biosynthetic process, phosphatidylethanolamine biosynthetic process, phospholipid metabolic process, small molecule metabolic process cytoplasm, cytosol ATP binding, choline kinase activity, ethanolamine kinase activity Human CHL1 Reactome UniProtKB {GO:0008344=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0005578=GO_REF:0000039, GO:0045177=GO_REF:0000019, GO:0002020=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0007165=PMID:9799093, GO:0043524=GO_REF:0000019, GO:0050890=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0016021=GO_REF:0000037, GO:0001764=GO_REF:0000019, GO:0007155=GO_REF:0000037} O00533 Neural cell adhesion molecule L1-like protein protein 20091012 {GO:0008344=IEA, GO:0005886=IEA, GO:0005578=IEA, GO:0045177=IEA, GO:0002020=IEA, GO:0030425=IEA, GO:0007165=TAS, GO:0043524=IEA, GO:0050890=IEA, GO:0007411=TAS, GO:0016021=IEA, GO:0001764=IEA, GO:0007155=IEA} adult locomotory behavior, axon guidance, cell adhesion, cognition, negative regulation of neuron apoptotic process, neuron migration, signal transduction apical part of cell, dendrite, integral to membrane, plasma membrane, proteinaceous extracellular matrix protease binding Human CHM PINC UniProtKB {GO:0018344=PMID:8380507, GO:0001568=GO_REF:0000019, GO:0005968=GO_REF:0000002, GO:0004663=GO_REF:0000002, GO:0007601=GO_REF:0000037, GO:0006886=GO_REF:0000002, GO:0050896=GO_REF:0000037, GO:0005096=GO_REF:0000037} P24386 Rab proteins geranylgeranyltransferase component A 1 protein 20031119 {GO:0018344=TAS, GO:0001568=IEA, GO:0005968=IEA, GO:0004663=IEA, GO:0007601=IEA, GO:0006886=IEA, GO:0050896=IEA, GO:0005096=IEA} blood vessel development, intracellular protein transport, protein geranylgeranylation, response to stimulus, visual perception Rab-protein geranylgeranyltransferase complex GTPase activator activity, Rab geranylgeranyltransferase activity Human CHML PINC UniProtKB {GO:0005968=GO_REF:0000002, GO:0004663=GO_REF:0000002, GO:0007601=PMID:1301160, GO:0006886=GO_REF:0000002, GO:0005096=GO_REF:0000037} P26374 Rab proteins geranylgeranyltransferase component A 2 protein 20030904 {GO:0005968=IEA, GO:0004663=IEA, GO:0007601=TAS, GO:0006886=IEA, GO:0005096=IEA} intracellular protein transport, visual perception Rab-protein geranylgeranyltransferase complex GTPase activator activity, Rab geranylgeranyltransferase activity Human CHMP1A IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0007076=PMID:11559747, GO:0000794=PMID:11559747, GO:0005815=PMID:11559748, GO:0019904=PMID:17928862, GO:0016458=PMID:11559747, GO:0015031=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0016363=PMID:11559747, GO:0045749=PMID:11559747, GO:0012505=PMID:11559748, GO:0045014=PMID:9837962, GO:0000910=PMID:19129479, GO:0008270=PMID:8863740, GO:0016192=PMID:11559748, GO:0045892=PMID:11559747, GO:0008237=PMID:8863740, GO:0010008=GO_REF:0000039, GO:0005769=PMID:11559748} Q9HD42 Charged multivesicular body protein 1a protein 20130415 {GO:0005515=IPI, GO:0007076=IDA, GO:0000794=IDA, GO:0005815=IDA, GO:0019904=IPI, GO:0016458=IDA, GO:0015031=IEA, GO:0006351=IEA, GO:0016363=IDA, GO:0045749=IMP, GO:0012505=IDA, GO:0045014=IDA, GO:0000910=IMP, GO:0008270=TAS, GO:0016192=IDA, GO:0045892=IDA, GO:0008237=TAS, GO:0010008=IEA, GO:0005769=IDA} cytokinesis, gene silencing, mitotic chromosome condensation, negative regulation of S phase of mitotic cell cycle, negative regulation of transcription by glucose, negative regulation of transcription, DNA-dependent, protein transport, transcription, DNA-dependent, vesicle-mediated transport condensed nuclear chromosome, early endosome, endomembrane system, endosome membrane, microtubule organizing center, nuclear matrix metallopeptidase activity, protein binding, protein domain specific binding, zinc ion binding Human UniProtKB:O95630 CHMP1B IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0000910=PMID:19129479, GO:0007049=GO_REF:0000037, GO:0019904=PMID:17928862, GO:0031902=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0005829=GO_REF:0000039} Q7LBR1 Charged multivesicular body protein 1b protein 20130415 {GO:0005515=IPI, GO:0000910=IMP, GO:0007049=IEA, GO:0019904=IPI, GO:0031902=IEA, GO:0015031=IEA, GO:0005829=IEA} cell cycle, cytokinesis, protein transport cytosol, late endosome membrane protein binding, protein domain specific binding Human UniProtKB:O95630 CHMP2A Reactome UniProtKB {GO:0005515=PMID:19525971, GO:0016197=Reactome:REACT_27258, GO:0019904=PMID:17928862, GO:0031902=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0016044=Reactome:REACT_11123, GO:0005829=Reactome:REACT_27290} O43633 Charged multivesicular body protein 2a protein 20130301 {GO:0005515=IPI, GO:0016197=TAS, GO:0019904=IPI, GO:0031902=IEA, GO:0015031=IEA, GO:0016044=TAS, GO:0005829=TAS} cellular membrane organization, endosomal transport, protein transport cytosol, late endosome membrane protein binding, protein domain specific binding Human CHMP2B HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005622=GO_REF:0000054, GO:0008219=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0016197=Reactome:REACT_27258, GO:0019904=PMID:17928862, GO:0031902=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0015031=GO_REF:0000037, GO:0016044=Reactome:REACT_11123, GO:0005829=Reactome:REACT_27290} Q9UQN3 Charged multivesicular body protein 2b protein 20101115 {GO:0005739=IDA, GO:0005622=IDA, GO:0008219=IEA, GO:0005737=IDA, GO:0016197=TAS, GO:0019904=IPI, GO:0031902=IEA, GO:0005634=IDA, GO:0015031=IEA, GO:0016044=TAS, GO:0005829=TAS} cell death, cellular membrane organization, endosomal transport, protein transport cytoplasm, cytosol, intracellular, late endosome membrane, mitochondrion, nucleus protein domain specific binding Human CHMP3 IntAct UniProtKB {GO:0005515=PMID:19615732, GO:0007049=GO_REF:0000037, GO:0016197=Reactome:REACT_27258, GO:0031902=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0016044=Reactome:REACT_11123, GO:0005829=Reactome:REACT_27290, GO:0051301=GO_REF:0000037} Q9Y3E7 Charged multivesicular body protein 3 protein 20130415 {GO:0005515=IPI, GO:0007049=IEA, GO:0016197=TAS, GO:0031902=IEA, GO:0006915=IEA, GO:0015031=IEA, GO:0016044=TAS, GO:0005829=TAS, GO:0051301=IEA} apoptotic process, cell cycle, cell division, cellular membrane organization, endosomal transport, protein transport cytosol, late endosome membrane protein binding Human UniProtKB:O95630 CHMP4A Reactome UniProtKB {GO:0016197=Reactome:REACT_27258, GO:0031902=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0016044=Reactome:REACT_11123, GO:0030659=GO_REF:0000039, GO:0005829=Reactome:REACT_27290, GO:0008289=GO_REF:0000037} Q9BY43 Charged multivesicular body protein 4a protein 20130301 {GO:0016197=TAS, GO:0031902=IEA, GO:0015031=IEA, GO:0016044=TAS, GO:0030659=IEA, GO:0005829=TAS, GO:0008289=IEA} cellular membrane organization, endosomal transport, protein transport cytoplasmic vesicle membrane, cytosol, late endosome membrane lipid binding Human CHMP4B Reactome UniProtKB {GO:0005515=PMID:20208530, GO:0016197=Reactome:REACT_27258, GO:0031902=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0016044=Reactome:REACT_11123, GO:0005829=Reactome:REACT_27290} Q9H444 Charged multivesicular body protein 4b protein 20130301 {GO:0005515=IPI, GO:0016197=TAS, GO:0031902=IEA, GO:0015031=IEA, GO:0016044=TAS, GO:0005829=TAS} cellular membrane organization, endosomal transport, protein transport cytosol, late endosome membrane protein binding Human CHMP4C Reactome UniProtKB {GO:0016197=Reactome:REACT_27258, GO:0031902=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0016044=Reactome:REACT_11123, GO:0005829=Reactome:REACT_27290} Q96CF2 Charged multivesicular body protein 4c protein 20130301 {GO:0016197=TAS, GO:0031902=IEA, GO:0015031=IEA, GO:0016044=TAS, GO:0005829=TAS} cellular membrane organization, endosomal transport, protein transport cytosol, late endosome membrane Human CHMP5 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0001919=GO_REF:0000019, GO:0016197=Reactome:REACT_27258, GO:0008333=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0007040=GO_REF:0000019, GO:0016044=Reactome:REACT_11123, GO:0010008=GO_REF:0000039, GO:0005829=Reactome:REACT_27184} Q9NZZ3 Charged multivesicular body protein 5 protein 20130415 {GO:0005515=IPI, GO:0001919=IEA, GO:0016197=TAS, GO:0008333=IEA, GO:0005634=IEA, GO:0015031=IEA, GO:0007040=IEA, GO:0016044=TAS, GO:0010008=IEA, GO:0005829=TAS} cellular membrane organization, endosomal transport, endosome to lysosome transport, lysosome organization, protein transport, regulation of receptor recycling cytosol, endosome membrane, nucleus protein binding Human UniProtKB:O95630 CHMP6 Reactome UniProtKB {GO:0047485=PMID:18606141, GO:0016197=Reactome:REACT_27258, GO:0031902=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0016044=Reactome:REACT_11123, GO:0005829=Reactome:REACT_27290, GO:0012505=GO_REF:0000039} Q96FZ7 Charged multivesicular body protein 6 protein 20100729 {GO:0047485=IPI, GO:0016197=TAS, GO:0031902=IEA, GO:0015031=IEA, GO:0016044=TAS, GO:0005829=TAS, GO:0012505=IEA} cellular membrane organization, endosomal transport, protein transport cytosol, endomembrane system, late endosome membrane protein N-terminus binding Human CHMP7 HPA UniProtKB {GO:0000815=PMID:16856878, GO:0005737=GO_REF:0000052, GO:0045324=PMID:16856878, GO:0016197=Reactome:REACT_27258, GO:0008565=PMID:16856878, GO:0005634=GO_REF:0000052, GO:0016044=Reactome:REACT_11123, GO:0005829=Reactome:REACT_27290} Q8WUX9 Charged multivesicular body protein 7 protein 20110516 {GO:0000815=IDA, GO:0005737=IDA, GO:0045324=IMP, GO:0016197=TAS, GO:0008565=IMP, GO:0005634=IDA, GO:0016044=TAS, GO:0005829=TAS} cellular membrane organization, endosomal transport, late endosome to vacuole transport ESCRT III complex, cytoplasm, cytosol, nucleus protein transporter activity Human CHN1 Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0048013=GO_REF:0000024, GO:0007264=Reactome:REACT_11044, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_9982, GO:0005622=GO_REF:0000002, GO:0035556=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0008045=GO_REF:0000024, GO:0032314=GO_REF:0000019, GO:0046875=GO_REF:0000019, GO:0005070=PMID:8336731, GO:0050770=GO_REF:0000024, GO:0005096=GO_REF:0000037} P15882 N-chimaerin protein 20130301 {GO:0051056=TAS, GO:0048013=ISS, GO:0007264=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0005622=IEA, GO:0035556=IEA, GO:0007165=IEA, GO:0008045=ISS, GO:0032314=IEA, GO:0046875=IEA, GO:0005070=TAS, GO:0050770=ISS, GO:0005096=IEA} ephrin receptor signaling pathway, intracellular signal transduction, motor neuron axon guidance, regulation of Rac GTPase activity, regulation of axonogenesis, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular GTPase activator activity, SH3/SH2 adaptor activity, ephrin receptor binding, metal ion binding Human CHN2 GOC UniProtKB {GO:0043547=PMID:7614486, GO:0035556=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0007264=Reactome:REACT_11044, GO:0005070=PMID:8175705, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} P52757 Beta-chimaerin protein 20130413 {GO:0043547=TAS, GO:0035556=IEA, GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0016020=IEA, GO:0007264=TAS, GO:0005070=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0005096=IEA} intracellular signal transduction, positive regulation of GTPase activity, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular, membrane GTPase activator activity, SH3/SH2 adaptor activity, metal ion binding Human CHODL HGNC UniProtKB {GO:0048471=PMID:12079284, GO:0005737=PMID:22042635, GO:0007517=PMID:12079284, GO:0005540=PMID:12079284, GO:0030246=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q9H9P2 Chondrolectin protein 20051208 {GO:0048471=IDA, GO:0005737=IDA, GO:0007517=NAS, GO:0005540=IDA, GO:0030246=IEA, GO:0016021=IEA} muscle organ development cytoplasm, integral to membrane, perinuclear region of cytoplasm carbohydrate binding, hyaluronic acid binding Human CHORDC1 IntAct UniProtKB {GO:0005515=PMID:19875381, GO:0080134=GO_REF:0000024, GO:0061077=GO_REF:0000024, GO:0051879=PMID:19875381, GO:0006950=GO_REF:0000037, GO:0008270=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:2000299=GO_REF:0000019, GO:0010824=GO_REF:0000019} Q9UHD1 Cysteine and histidine-rich domain-containing protein 1 protein 20130415 {GO:0005515=IPI, GO:0080134=ISS, GO:0061077=ISS, GO:0051879=IPI, GO:0006950=IEA, GO:0008270=IEA, GO:0005575=ND, GO:2000299=IEA, GO:0010824=IEA} chaperone-mediated protein folding, negative regulation of Rho-dependent protein serine/threonine kinase activity, regulation of centrosome duplication, regulation of response to stress, response to stress cellular_component Hsp90 protein binding, protein binding, zinc ion binding Human UniProtKB:P07900 CHP2 UniProtKB UniProtKB {GO:0005515=PMID:21392185, GO:0005737=PMID:21392185, GO:0008284=PMID:21392185, GO:0005886=PMID:21392185, GO:0045944=PMID:18815128, GO:0005509=PMID:21392185, GO:0010922=PMID:18815128, GO:0071277=PMID:18815128, GO:0042307=PMID:18815128, GO:0005634=PMID:21392185, GO:0070886=PMID:18815128, GO:0015031=GO_REF:0000037} O43745 Calcineurin B homologous protein 2 protein 20120626 {GO:0005515=IPI, GO:0005737=IDA, GO:0008284=IDA, GO:0005886=IDA, GO:0045944=IDA, GO:0005509=IDA, GO:0010922=IDA, GO:0071277=IDA, GO:0042307=IDA, GO:0005634=IDA, GO:0070886=IDA, GO:0015031=IEA} cellular response to calcium ion, positive regulation of calcineurin-NFAT signaling cascade, positive regulation of cell proliferation, positive regulation of phosphatase activity, positive regulation of protein import into nucleus, positive regulation of transcription from RNA polymerase II promoter, protein transport cytoplasm, nucleus, plasma membrane calcium ion binding, protein binding Human CHPF Reactome UniProtKB {GO:0030206=Reactome:REACT_120989, GO:0000139=Reactome:REACT_121192, GO:0016758=GO_REF:0000002, GO:0005975=Reactome:REACT_474, GO:0032580=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121315, GO:0050510=GO_REF:0000003, GO:0047238=GO_REF:0000003, GO:0046872=GO_REF:0000037} Q8IZ52 Chondroitin sulfate synthase 2 protein 20130301 {GO:0030206=TAS, GO:0000139=TAS, GO:0016758=IEA, GO:0005975=TAS, GO:0032580=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0030204=TAS, GO:0030203=TAS, GO:0050510=IEA, GO:0047238=IEA, GO:0046872=IEA} carbohydrate metabolic process, chondroitin sulfate biosynthetic process, chondroitin sulfate metabolic process, glycosaminoglycan metabolic process, small molecule metabolic process Golgi cisterna membrane, Golgi membrane, integral to membrane N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity, glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity, metal ion binding, transferase activity, transferring hexosyl groups Human CHPT1 Reactome UniProtKB {GO:0006629=PMID:10893425, GO:0006663=PMID:10893425, GO:0044281=Reactome:REACT_111217, GO:0008654=GO_REF:0000002, GO:0001558=PMID:10893425, GO:0046872=GO_REF:0000037, GO:0043231=PMID:10893425, GO:0019992=PMID:10893425, GO:0016780=GO_REF:0000002, GO:0000139=Reactome:REACT_120834, GO:0016020=PMID:10893425, GO:0016021=GO_REF:0000037, GO:0004142=Reactome:REACT_120834, GO:0006644=Reactome:REACT_120870, GO:0006657=PMID:10893425, GO:0046474=Reactome:REACT_121401, GO:0006656=Reactome:REACT_121238} Q8WUD6 Cholinephosphotransferase 1 protein 20110824 {GO:0006629=TAS, GO:0006663=IDA, GO:0044281=TAS, GO:0008654=IEA, GO:0001558=NAS, GO:0046872=IEA, GO:0043231=NAS, GO:0019992=NAS, GO:0016780=IEA, GO:0000139=TAS, GO:0016020=NAS, GO:0016021=IEA, GO:0004142=TAS, GO:0006644=TAS, GO:0006657=NAS, GO:0046474=TAS, GO:0006656=TAS} CDP-choline pathway, glycerophospholipid biosynthetic process, lipid metabolic process, phosphatidylcholine biosynthetic process, phospholipid biosynthetic process, phospholipid metabolic process, platelet activating factor biosynthetic process, regulation of cell growth, small molecule metabolic process Golgi membrane, integral to membrane, intracellular membrane-bounded organelle, membrane diacylglycerol binding, diacylglycerol cholinephosphotransferase activity, metal ion binding, phosphotransferase activity, for other substituted phosphate groups Human CHRAC1 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0008623=PMID:10880450, GO:0008622=PMID:10880450, GO:0046982=GO_REF:0000002, GO:0003887=PMID:10880450, GO:0006338=PMID:10880450, GO:0003677=PMID:10880450} Q9NRG0 Chromatin accessibility complex protein 1 protein 20030110 {GO:0043565=IEA, GO:0005622=IEA, GO:0008623=NAS, GO:0008622=NAS, GO:0046982=IEA, GO:0003887=NAS, GO:0006338=NAS, GO:0003677=NAS} chromatin remodeling CHRAC, epsilon DNA polymerase complex, intracellular DNA binding, DNA-directed DNA polymerase activity, protein heterodimerization activity, sequence-specific DNA binding Human CHRD BHF-UCL UniProtKB {GO:0005515=PMID:21988832, GO:0030336=PMID:16449796, GO:0001707=GO_REF:0000019, GO:0033504=PMID:11790302, GO:0021919=PMID:11472837, GO:0002053=PMID:18533030, GO:0005615=PMID:16449796, GO:0001649=GO_REF:0000019, GO:0001702=GO_REF:0000019, GO:0045785=PMID:16449796, GO:0030514=PMID:11472837, GO:0001501=PMID:9782094, GO:0045668=PMID:18533030, GO:0019955=PMID:16449796, GO:0030900=GO_REF:0000019, GO:0008201=GO_REF:0000019, GO:0045545=GO_REF:0000019} Q9H2X0 Chordin protein 20120508 {GO:0005515=IPI, GO:0030336=IDA, GO:0001707=IEA, GO:0033504=TAS, GO:0021919=IMP, GO:0002053=IMP, GO:0005615=NAS, GO:0001649=IEA, GO:0001702=IEA, GO:0045785=IDA, GO:0030514=IMP, GO:0001501=TAS, GO:0045668=IMP, GO:0019955=NAS, GO:0030900=IEA, GO:0008201=IEA, GO:0045545=IEA} BMP signaling pathway involved in spinal cord dorsal/ventral patterning, floor plate development, forebrain development, gastrulation with mouth forming second, mesoderm formation, negative regulation of BMP signaling pathway, negative regulation of cell migration, negative regulation of osteoblast differentiation, osteoblast differentiation, positive regulation of cell adhesion, positive regulation of mesenchymal cell proliferation, skeletal system development extracellular space cytokine binding, heparin binding, protein binding, syndecan binding Human CHRDL1 Reactome UniProtKB {GO:0048749=PMID:22284829, GO:0001503=GO_REF:0000037, GO:0001654=PMID:22284829, GO:0005576=Reactome:REACT_12026, GO:0030509=Reactome:REACT_12034, GO:0030154=GO_REF:0000037, GO:0007399=GO_REF:0000037} Q9BU40 Chordin-like protein 1 protein 20130301 {GO:0048749=IMP, GO:0001503=IEA, GO:0001654=IMP, GO:0005576=TAS, GO:0030509=TAS, GO:0030154=IEA, GO:0007399=IEA} BMP signaling pathway, cell differentiation, compound eye development, eye development, nervous system development, ossification extracellular region Human CHRDL2 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0001503=GO_REF:0000037, GO:0051216=GO_REF:0000037, GO:0005576=GO_REF:0000039, GO:0030154=GO_REF:0000037} Q6WN34 Chordin-like protein 2 protein 20090616 {GO:0005739=IDA, GO:0001503=IEA, GO:0051216=IEA, GO:0005576=IEA, GO:0030154=IEA} cartilage development, cell differentiation, ossification extracellular region, mitochondrion Human CHRFAM7A UniProtKB UniProtKB {GO:0005230=GO_REF:0000002, GO:0045211=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q494W8 CHRNA7-FAM7A fusion protein protein 20130413 {GO:0005230=IEA, GO:0045211=IEA, GO:0016021=IEA} integral to membrane, postsynaptic membrane extracellular ligand-gated ion channel activity Human UniProtKB-KW:KW-0812 CHRM1 ENSEMBL UniProtKB {GO:0008284=PMID:2739737, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_22436, GO:0008283=PMID:1905013, GO:0043269=GO_REF:0000002, GO:0007205=PMID:9603968, GO:0032279=GO_REF:0000019, GO:0040012=GO_REF:0000019, GO:0043270=PMID:14657398, GO:0045211=GO_REF:0000039, GO:0008144=GO_REF:0000019, GO:0043679=GO_REF:0000019, GO:0060079=GO_REF:0000002, GO:0014069=GO_REF:0000019, GO:0007274=GO_REF:0000019, GO:1900274=GO_REF:0000002, GO:0007213=PMID:8139539, GO:0016907=GO_REF:0000019, GO:0007399=PMID:2739737, GO:0007165=PMID:9614217, GO:0016020=PMID:7925360, GO:0007186=PMID:7925360, GO:0005887=GO_REF:0000002, GO:0004435=PMID:9614217, GO:0007207=PMID:8139539, GO:0006464=PMID:1411529} Q96RH1 Muscarinic acetylcholine receptor M1 protein 20130413 {GO:0008284=TAS, GO:0030054=IEA, GO:0005886=TAS, GO:0008283=TAS, GO:0043269=IEA, GO:0007205=TAS, GO:0032279=IEA, GO:0040012=IEA, GO:0043270=IGI, GO:0045211=IEA, GO:0008144=IEA, GO:0043679=IEA, GO:0060079=IEA, GO:0014069=IEA, GO:0007274=IEA, GO:1900274=IEA, GO:0007213=TAS, GO:0016907=IEA, GO:0007399=TAS, GO:0007165=TAS, GO:0016020=TAS, GO:0007186=TAS, GO:0005887=IEA, GO:0004435=TAS, GO:0007207=TAS, GO:0006464=TAS} G-protein coupled acetylcholine receptor signaling pathway, G-protein coupled receptor signaling pathway, cell proliferation, cellular protein modification process, nervous system development, neuromuscular synaptic transmission, phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway, positive regulation of cell proliferation, positive regulation of ion transport, protein kinase C-activating G-protein coupled receptor signaling pathway, regulation of excitatory postsynaptic membrane potential, regulation of ion transport, regulation of locomotion, regulation of phospholipase C activity, signal transduction asymmetric synapse, axon terminus, cell junction, integral to plasma membrane, membrane, plasma membrane, postsynaptic density, postsynaptic membrane G-protein coupled acetylcholine receptor activity, drug binding, phosphatidylinositol phospholipase C activity Human Ensembl:ENSRNOP00000024785 CHRM2 LIFEdb UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000054, GO:0008016=GO_REF:0000002, GO:0009615=PMID:16548883, GO:0043269=GO_REF:0000002, GO:0016907=GO_REF:0000019, GO:0007399=PMID:2739737, GO:0007186=PMID:9603968, GO:0005887=GO_REF:0000002, GO:0007187=PMID:10895079, GO:0045211=GO_REF:0000039, GO:0007207=PMID:2739737, GO:0030815=GO_REF:0000002, GO:0007188=PMID:8139539} P08172 Muscarinic acetylcholine receptor M2 protein 20100607 {GO:0030054=IEA, GO:0005886=IDA, GO:0008016=IEA, GO:0009615=IEP, GO:0043269=IEA, GO:0016907=IEA, GO:0007399=TAS, GO:0007186=TAS, GO:0005887=IEA, GO:0007187=TAS, GO:0045211=IEA, GO:0007207=TAS, GO:0030815=IEA, GO:0007188=TAS} G-protein coupled receptor signaling pathway, G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, negative regulation of cAMP metabolic process, nervous system development, phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway, regulation of heart contraction, regulation of ion transport, response to virus cell junction, integral to plasma membrane, plasma membrane, postsynaptic membrane G-protein coupled acetylcholine receptor activity Human CHRM3 Reactome UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_22436, GO:0008283=PMID:8063729, GO:0044281=Reactome:REACT_111217, GO:0030425=GO_REF:0000019, GO:0043269=GO_REF:0000002, GO:0032279=GO_REF:0000019, GO:0006939=GO_REF:0000019, GO:0016323=GO_REF:0000039, GO:0045987=GO_REF:0000019, GO:0008144=GO_REF:0000019, GO:0045211=GO_REF:0000039, GO:0042166=GO_REF:0000019, GO:0043679=GO_REF:0000019, GO:0004872=PMID:10940357, GO:0007586=GO_REF:0000019, GO:1900274=GO_REF:0000002, GO:0016907=GO_REF:0000019, GO:0007399=PMID:2739737, GO:0007165=PMID:10940357, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0007186=PMID:9603968, GO:0004435=PMID:1905013, GO:0005887=GO_REF:0000002, GO:0003056=GO_REF:0000019, GO:0006464=PMID:10051746} P20309 Muscarinic acetylcholine receptor M3 protein 20130111 {GO:0030054=IEA, GO:0005886=TAS, GO:0008283=TAS, GO:0044281=TAS, GO:0030425=IEA, GO:0043269=IEA, GO:0032279=IEA, GO:0006939=IEA, GO:0016323=IEA, GO:0045987=IEA, GO:0008144=IEA, GO:0045211=IEA, GO:0042166=IEA, GO:0043679=IEA, GO:0004872=TAS, GO:0007586=IEA, GO:1900274=IEA, GO:0016907=IEA, GO:0007399=TAS, GO:0007165=TAS, GO:0006112=TAS, GO:0050796=TAS, GO:0007186=TAS, GO:0004435=TAS, GO:0005887=IEA, GO:0003056=IEA, GO:0006464=TAS} G-protein coupled receptor signaling pathway, cell proliferation, cellular protein modification process, digestion, energy reserve metabolic process, nervous system development, positive regulation of smooth muscle contraction, regulation of insulin secretion, regulation of ion transport, regulation of phospholipase C activity, regulation of vascular smooth muscle contraction, signal transduction, small molecule metabolic process, smooth muscle contraction asymmetric synapse, axon terminus, basolateral plasma membrane, cell junction, dendrite, integral to plasma membrane, plasma membrane, postsynaptic membrane G-protein coupled acetylcholine receptor activity, acetylcholine binding, drug binding, phosphatidylinositol phospholipase C activity, receptor activity Human CHRM4 Reactome UniProtKB {GO:0010033=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_22289, GO:0008283=PMID:2739737, GO:0007197=GO_REF:0000019, GO:0014056=GO_REF:0000002, GO:0007213=PMID:3443095, GO:0016907=GO_REF:0000019, GO:0040012=GO_REF:0000002, GO:0007165=PMID:9603968, GO:0005887=GO_REF:0000002, GO:0045211=GO_REF:0000039, GO:0007166=PMID:2739737} P08173 Muscarinic acetylcholine receptor M4 protein 20090210 {GO:0010033=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0008283=TAS, GO:0007197=IEA, GO:0014056=IEA, GO:0007213=TAS, GO:0016907=IEA, GO:0040012=IEA, GO:0007165=TAS, GO:0005887=IEA, GO:0045211=IEA, GO:0007166=TAS} G-protein coupled acetylcholine receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway, cell proliferation, cell surface receptor signaling pathway, regulation of acetylcholine secretion, regulation of locomotion, response to organic substance, signal transduction cell junction, integral to plasma membrane, plasma membrane, postsynaptic membrane G-protein coupled acetylcholine receptor activity Human CHRM5 Reactome UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_22436, GO:0008283=PMID:8063729, GO:0015872=GO_REF:0000019, GO:0007197=PMID:8663391, GO:1900274=GO_REF:0000002, GO:0007213=PMID:3272174, GO:0016907=GO_REF:0000019, GO:0060304=GO_REF:0000019, GO:0043269=GO_REF:0000002, GO:0005887=GO_REF:0000002, GO:0004435=PMID:1905013, GO:0045211=GO_REF:0000039, GO:0030815=GO_REF:0000002} P08912 Muscarinic acetylcholine receptor M5 protein 20130111 {GO:0030054=IEA, GO:0005886=TAS, GO:0008283=TAS, GO:0015872=IEA, GO:0007197=TAS, GO:1900274=IEA, GO:0007213=TAS, GO:0016907=IEA, GO:0060304=IEA, GO:0043269=IEA, GO:0005887=IEA, GO:0004435=TAS, GO:0045211=IEA, GO:0030815=IEA} G-protein coupled acetylcholine receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway, cell proliferation, dopamine transport, negative regulation of cAMP metabolic process, regulation of ion transport, regulation of phosphatidylinositol dephosphorylation, regulation of phospholipase C activity cell junction, integral to plasma membrane, plasma membrane, postsynaptic membrane G-protein coupled acetylcholine receptor activity, phosphatidylinositol phospholipase C activity Human CHRNA1 BHF-UCL UniProtKB {GO:0048630=PMID:18252226, GO:0005230=GO_REF:0000002, GO:0031594=PMID:8872460, GO:0030054=GO_REF:0000037, GO:0005886=PMID:8872460, GO:0007268=Reactome:REACT_13685, GO:0019228=PMID:8872460, GO:0046716=PMID:8872460, GO:0050905=PMID:9546329, GO:0050881=PMID:18252226, GO:0007528=PMID:9221765, GO:0045211=PMID:18252226, GO:0015464=PMID:8872460, GO:0042391=PMID:8872460, GO:0006810=PMID:7619526, GO:0042166=PMID:8872460, GO:0009986=PMID:12928480, GO:0007274=PMID:9221765, GO:0005892=PMID:8872460, GO:0007165=PMID:7619526, GO:0003009=PMID:8872460, GO:0016021=GO_REF:0000038, GO:0070050=PMID:8872460, GO:0005216=PMID:6688857, GO:0004889=PMID:8872460} P02708 Acetylcholine receptor subunit alpha protein 20080923 {GO:0048630=IMP, GO:0005230=IEA, GO:0031594=ISS, GO:0030054=IEA, GO:0005886=ISS, GO:0007268=TAS, GO:0019228=IMP, GO:0046716=IMP, GO:0050905=IMP, GO:0050881=IMP, GO:0007528=IMP, GO:0045211=NAS, GO:0015464=ISS, GO:0042391=IMP, GO:0006810=TAS, GO:0042166=ISS, GO:0009986=IDA, GO:0007274=IMP, GO:0005892=ISS, GO:0007165=TAS, GO:0003009=IMP, GO:0016021=IEA, GO:0070050=IMP, GO:0005216=TAS, GO:0004889=ISS} muscle cell homeostasis, musculoskeletal movement, neuromuscular junction development, neuromuscular process, neuromuscular synaptic transmission, neuron homeostasis, regulation of action potential in neuron, regulation of membrane potential, signal transduction, skeletal muscle contraction, skeletal muscle tissue growth, synaptic transmission, transport acetylcholine-gated channel complex, cell junction, cell surface, integral to membrane, neuromuscular junction, plasma membrane, postsynaptic membrane acetylcholine binding, acetylcholine receptor activity, acetylcholine-activated cation-selective channel activity, extracellular ligand-gated ion channel activity, ion channel activity contributes_to Human UniProtKB:P04756 CHRNA2 Reactome UniProtKB {GO:0007165=PMID:8906617, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_22409, GO:0015464=PMID:8906617, GO:0045211=GO_REF:0000039, GO:0007268=Reactome:REACT_13685, GO:0016021=PMID:8906617, GO:0005892=PMID:8906617, GO:0004889=PMID:8906617, GO:0006811=PMID:8906617, GO:0071944=GO_REF:0000019} Q15822 Neuronal acetylcholine receptor subunit alpha-2 protein 20100429 {GO:0007165=IDA, GO:0030054=IEA, GO:0005886=TAS, GO:0015464=IDA, GO:0045211=IEA, GO:0007268=TAS, GO:0016021=NAS, GO:0005892=IDA, GO:0004889=IDA, GO:0006811=NAS, GO:0071944=IEA} ion transport, signal transduction, synaptic transmission acetylcholine-gated channel complex, cell junction, cell periphery, integral to membrane, plasma membrane, postsynaptic membrane acetylcholine receptor activity, acetylcholine-activated cation-selective channel activity Human CHRNA3 Reactome UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_22438, GO:0007268=Reactome:REACT_13685, GO:0006940=GO_REF:0000024, GO:0060084=PMID:11450844, GO:0014056=GO_REF:0000024, GO:0030425=GO_REF:0000024, GO:0007171=GO_REF:0000024, GO:0015464=PMID:8906617, GO:0045211=GO_REF:0000039, GO:0042391=GO_REF:0000024, GO:0042166=PMID:8906617, GO:0043025=GO_REF:0000024, GO:0007626=GO_REF:0000024, GO:0006811=PMID:8906617, GO:0015276=PMID:20438829, GO:0060079=GO_REF:0000024, GO:0014069=GO_REF:0000024, GO:0005892=PMID:8906617, GO:0007271=GO_REF:0000024, GO:0007399=PMID:11450844, GO:0035095=PMID:18227835, GO:0048814=GO_REF:0000024, GO:0007165=PMID:8906617, GO:0016021=PMID:8906617, GO:0004889=PMID:8906617} P32297 Neuronal acetylcholine receptor subunit alpha-3 protein 20100429 {GO:0030054=IEA, GO:0005886=TAS, GO:0007268=TAS, GO:0006940=ISS, GO:0060084=IMP, GO:0014056=ISS, GO:0030425=ISS, GO:0007171=ISS, GO:0015464=IDA, GO:0045211=IEA, GO:0042391=ISS, GO:0042166=IC, GO:0043025=ISS, GO:0007626=ISS, GO:0006811=NAS, GO:0015276=TAS, GO:0060079=ISS, GO:0014069=ISS, GO:0005892=IDA, GO:0007271=ISS, GO:0007399=IMP, GO:0035095=IMP, GO:0048814=ISS, GO:0007165=IDA, GO:0016021=NAS, GO:0004889=IDA} activation of transmembrane receptor protein tyrosine kinase activity, behavioral response to nicotine, ion transport, locomotory behavior, nervous system development, regulation of acetylcholine secretion, regulation of dendrite morphogenesis, regulation of excitatory postsynaptic membrane potential, regulation of membrane potential, regulation of smooth muscle contraction, signal transduction, synaptic transmission, synaptic transmission involved in micturition, synaptic transmission, cholinergic acetylcholine-gated channel complex, cell junction, dendrite, integral to membrane, neuronal cell body, plasma membrane, postsynaptic density, postsynaptic membrane acetylcholine binding, acetylcholine receptor activity, acetylcholine-activated cation-selective channel activity, ligand-gated ion channel activity Human CHRNA4 Reactome UniProtKB {GO:0051899=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_22438, GO:0007268=Reactome:REACT_13685, GO:0030425=GO_REF:0000024, GO:0014059=GO_REF:0000024, GO:0015464=PMID:8906617, GO:0045211=GO_REF:0000039, GO:0042391=GO_REF:0000024, GO:0042166=PMID:8906617, GO:0043025=GO_REF:0000024, GO:0007626=GO_REF:0000019, GO:0006816=GO_REF:0000024, GO:0006979=PMID:16332175, GO:0006811=PMID:8906617, GO:0015276=PMID:20438829, GO:0001666=PMID:12189247, GO:0005892=PMID:8906617, GO:0007271=GO_REF:0000024, GO:0019233=GO_REF:0000024, GO:0035095=PMID:17955458, GO:0042113=GO_REF:0000024, GO:0007165=PMID:8906617, GO:0060080=GO_REF:0000024, GO:0006281=PMID:16332175, GO:0050890=PMID:14623738, GO:0016020=GO_REF:0000024, GO:0050877=PMID:17613539, GO:0016021=PMID:8906617, GO:0001508=GO_REF:0000024, GO:0004889=PMID:20438829, GO:0009897=GO_REF:0000024, GO:0035094=PMID:12189247} P43681 Neuronal acetylcholine receptor subunit alpha-4 protein 20100429 {GO:0051899=ISS, GO:0030054=IEA, GO:0005886=TAS, GO:0007268=TAS, GO:0030425=ISS, GO:0014059=ISS, GO:0015464=IDA, GO:0045211=IEA, GO:0042391=ISS, GO:0042166=IC, GO:0043025=ISS, GO:0007626=IEA, GO:0006816=ISS, GO:0006979=IMP, GO:0006811=NAS, GO:0015276=TAS, GO:0001666=IDA, GO:0005892=IDA, GO:0007271=ISS, GO:0019233=ISS, GO:0035095=IMP, GO:0042113=ISS, GO:0007165=IDA, GO:0060080=ISS, GO:0006281=IMP, GO:0050890=IMP, GO:0016020=ISS, GO:0050877=IMP, GO:0016021=NAS, GO:0001508=ISS, GO:0004889=TAS, GO:0009897=ISS, GO:0035094=IDA} B cell activation, DNA repair, behavioral response to nicotine, calcium ion transport, cognition, ion transport, locomotory behavior, membrane depolarization, neurological system process, regulation of action potential, regulation of dopamine secretion, regulation of inhibitory postsynaptic membrane potential, regulation of membrane potential, response to hypoxia, response to nicotine, response to oxidative stress, sensory perception of pain, signal transduction, synaptic transmission, synaptic transmission, cholinergic acetylcholine-gated channel complex, cell junction, dendrite, external side of plasma membrane, integral to membrane, membrane, neuronal cell body, plasma membrane, postsynaptic membrane acetylcholine binding, acetylcholine receptor activity, acetylcholine-activated cation-selective channel activity, ligand-gated ion channel activity Human CHRNA5 Reactome UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_22409, GO:0007268=Reactome:REACT_13685, GO:0005892=PMID:1542648, GO:0035095=PMID:18227835, GO:0007165=PMID:9009220, GO:0045211=GO_REF:0000039, GO:0015464=PMID:1542648, GO:0006810=PMID:1542648, GO:0016021=GO_REF:0000038, GO:0004889=PMID:1542648, GO:0006811=GO_REF:0000002, GO:0015276=PMID:20438829} P30532 Neuronal acetylcholine receptor subunit alpha-5 protein 20100429 {GO:0030054=IEA, GO:0005886=TAS, GO:0007268=TAS, GO:0005892=IC, GO:0035095=IMP, GO:0007165=NAS, GO:0045211=IEA, GO:0015464=IDA, GO:0006810=NAS, GO:0016021=IEA, GO:0004889=NAS, GO:0006811=IEA, GO:0015276=TAS} behavioral response to nicotine, ion transport, signal transduction, synaptic transmission, transport acetylcholine-gated channel complex, cell junction, integral to membrane, plasma membrane, postsynaptic membrane acetylcholine receptor activity, acetylcholine-activated cation-selective channel activity, ligand-gated ion channel activity Human CHRNA7 Reactome UniProtKB {GO:0005230=GO_REF:0000002, GO:0008284=PMID:16280133, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_22243, GO:0007268=Reactome:REACT_13685, GO:0042221=PMID:18387948, GO:0042803=PMID:8145738, GO:0000187=PMID:10771023, GO:0001540=PMID:10681545, GO:0045211=GO_REF:0000039, GO:0015464=PMID:8906617, GO:0042166=PMID:8145738, GO:0006816=PMID:8145738, GO:0007613=PMID:10681545, GO:0006811=PMID:8906617, GO:0001666=PMID:12189247, GO:0006874=PMID:16280133, GO:0032720=PMID:12508119, GO:0045766=PMID:16280133, GO:0005892=PMID:8906617, GO:0007165=PMID:8906617, GO:0050890=PMID:10681545, GO:0015643=PMID:12508119, GO:0016021=PMID:8906617, GO:0004889=PMID:12508119, GO:0017081=PMID:8145738, GO:0035094=PMID:8145738} P36544 Neuronal acetylcholine receptor subunit alpha-7 protein 20100429 {GO:0005230=IEA, GO:0008284=IMP, GO:0030054=IEA, GO:0005886=TAS, GO:0007268=TAS, GO:0042221=IDA, GO:0042803=IDA, GO:0000187=IDA, GO:0001540=IPI, GO:0045211=IEA, GO:0015464=IDA, GO:0042166=IDA, GO:0006816=IDA, GO:0007613=NAS, GO:0006811=NAS, GO:0001666=IDA, GO:0006874=IMP, GO:0032720=IDA, GO:0045766=IMP, GO:0005892=IDA, GO:0007165=IDA, GO:0050890=NAS, GO:0015643=IDA, GO:0016021=NAS, GO:0004889=IDA, GO:0017081=IDA, GO:0035094=IDA} activation of MAPK activity, calcium ion transport, cellular calcium ion homeostasis, cognition, ion transport, memory, negative regulation of tumor necrosis factor production, positive regulation of angiogenesis, positive regulation of cell proliferation, response to chemical stimulus, response to hypoxia, response to nicotine, signal transduction, synaptic transmission acetylcholine-gated channel complex, cell junction, integral to membrane, plasma membrane, postsynaptic membrane acetylcholine binding, acetylcholine receptor activity, acetylcholine-activated cation-selective channel activity, beta-amyloid binding, chloride channel regulator activity, extracellular ligand-gated ion channel activity, protein homodimerization activity, toxic substance binding Human CHRNA9 Reactome UniProtKB {GO:0005262=GO_REF:0000037, GO:0042472=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_22243, GO:0045211=GO_REF:0000039, GO:0050910=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0007204=PMID:18420419, GO:0005892=GO_REF:0000019, GO:0004889=GO_REF:0000019} Q9UGM1 Neuronal acetylcholine receptor subunit alpha-9 protein 20130301 {GO:0005262=IEA, GO:0042472=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0045211=IEA, GO:0050910=IEA, GO:0007268=TAS, GO:0007204=IGI, GO:0005892=IEA, GO:0004889=IEA} detection of mechanical stimulus involved in sensory perception of sound, elevation of cytosolic calcium ion concentration, inner ear morphogenesis, synaptic transmission acetylcholine-gated channel complex, cell junction, plasma membrane, postsynaptic membrane acetylcholine-activated cation-selective channel activity, calcium channel activity Human CHRNB1 UniProtKB UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000038, GO:0045202=PMID:8872460, GO:0007274=PMID:8651643, GO:0005892=PMID:8872460, GO:0007271=PMID:8872460, GO:0035095=PMID:16874522, GO:0048747=PMID:8651643, GO:0007165=PMID:8872460, GO:0006936=PMID:8651643, GO:0005887=PMID:8872460, GO:0015464=PMID:8872460, GO:0045211=GO_REF:0000039, GO:0042391=GO_REF:0000024, GO:0042166=GO_REF:0000024, GO:0050877=PMID:11104662, GO:0001941=PMID:8651643, GO:0016021=GO_REF:0000038, GO:0004889=GO_REF:0000024, GO:0006812=PMID:8872460, GO:0015267=PMID:8872460, GO:0015276=GO_REF:0000024} P11230 Acetylcholine receptor subunit beta protein 20080623 {GO:0030054=IEA, GO:0005886=IEA, GO:0045202=IMP, GO:0007274=IMP, GO:0005892=IMP, GO:0007271=IMP, GO:0035095=IMP, GO:0048747=IMP, GO:0007165=IMP, GO:0006936=IMP, GO:0005887=NAS, GO:0015464=IMP, GO:0045211=IEA, GO:0042391=ISS, GO:0042166=ISS, GO:0050877=IMP, GO:0001941=IMP, GO:0016021=IEA, GO:0004889=ISS, GO:0006812=IMP, GO:0015267=IMP, GO:0015276=ISS} behavioral response to nicotine, cation transport, muscle contraction, muscle fiber development, neurological system process, neuromuscular synaptic transmission, postsynaptic membrane organization, regulation of membrane potential, signal transduction, synaptic transmission, cholinergic acetylcholine-gated channel complex, cell junction, integral to membrane, integral to plasma membrane, plasma membrane, postsynaptic membrane, synapse acetylcholine binding, acetylcholine receptor activity, acetylcholine-activated cation-selective channel activity, channel activity, ligand-gated ion channel activity contributes_to Human UniProtKB:P09690 CHRNB2 Reactome UniProtKB {GO:0030054=GO_REF:0000037, GO:0007605=GO_REF:0000024, GO:0042220=GO_REF:0000024, GO:0060084=GO_REF:0000024, GO:0045759=GO_REF:0000024, GO:0006939=GO_REF:0000024, GO:0045211=GO_REF:0000039, GO:0015464=PMID:8906617, GO:0042166=PMID:8906617, GO:0007613=PMID:15964197, GO:0001661=GO_REF:0000019, GO:0007612=PMID:15964197, GO:0015276=PMID:20438829, GO:0008306=GO_REF:0000024, GO:0051963=GO_REF:0000024, GO:0007271=GO_REF:0000024, GO:0005892=PMID:8906617, GO:0042113=GO_REF:0000024, GO:0032226=GO_REF:0000019, GO:0032225=GO_REF:0000024, GO:0008542=PMID:15964197, GO:0035176=GO_REF:0000024, GO:0050877=PMID:17900292, GO:0021631=GO_REF:0000024, GO:0009897=GO_REF:0000024, GO:0004889=PMID:20438829, GO:0051899=GO_REF:0000024, GO:0005886=Reactome:REACT_22438, GO:0030890=GO_REF:0000024, GO:0045471=GO_REF:0000024, GO:0007268=Reactome:REACT_13685, GO:0045188=GO_REF:0000019, GO:0014059=GO_REF:0000024, GO:0042053=GO_REF:0000024, GO:0021771=GO_REF:0000024, GO:0006816=GO_REF:0000024, GO:0007626=GO_REF:0000024, GO:0006811=PMID:8906617, GO:0001666=PMID:12189247, GO:0021952=GO_REF:0000024, GO:0021562=GO_REF:0000024, GO:0019233=GO_REF:0000024, GO:0035095=PMID:17559419, GO:0048814=GO_REF:0000024, GO:0007165=PMID:8906617, GO:0050890=PMID:17559419, GO:0042320=GO_REF:0000024, GO:0016021=PMID:8906617, GO:0007601=GO_REF:0000024, GO:0035094=PMID:12189247, GO:0033603=GO_REF:0000024} P17787 Neuronal acetylcholine receptor subunit beta-2 protein 20100429 {GO:0030054=IEA, GO:0007605=ISS, GO:0042220=ISS, GO:0060084=ISS, GO:0045759=ISS, GO:0006939=ISS, GO:0045211=IEA, GO:0015464=IDA, GO:0042166=IC, GO:0007613=IMP, GO:0001661=IEA, GO:0007612=IMP, GO:0015276=TAS, GO:0008306=ISS, GO:0051963=ISS, GO:0007271=ISS, GO:0005892=IDA, GO:0042113=ISS, GO:0032226=IEA, GO:0032225=ISS, GO:0008542=IMP, GO:0035176=ISS, GO:0050877=IMP, GO:0021631=ISS, GO:0009897=ISS, GO:0004889=TAS, GO:0051899=ISS, GO:0005886=TAS, GO:0030890=ISS, GO:0045471=ISS, GO:0007268=TAS, GO:0045188=IEA, GO:0014059=ISS, GO:0042053=ISS, GO:0021771=ISS, GO:0006816=ISS, GO:0007626=ISS, GO:0006811=NAS, GO:0001666=IDA, GO:0021952=ISS, GO:0021562=ISS, GO:0019233=ISS, GO:0035095=IMP, GO:0048814=ISS, GO:0007165=IDA, GO:0050890=IMP, GO:0042320=ISS, GO:0016021=NAS, GO:0007601=ISS, GO:0035094=IDA, GO:0033603=ISS} B cell activation, associative learning, behavioral response to nicotine, calcium ion transport, central nervous system projection neuron axonogenesis, cognition, conditioned taste aversion, ion transport, lateral geniculate nucleus development, learning, locomotory behavior, membrane depolarization, memory, negative regulation of action potential, neurological system process, optic nerve morphogenesis, positive regulation of B cell proliferation, positive regulation of dopamine secretion, positive regulation of synaptic transmission, dopaminergic, regulation of circadian sleep/wake cycle, REM sleep, regulation of circadian sleep/wake cycle, non-REM sleep, regulation of dendrite morphogenesis, regulation of dopamine metabolic process, regulation of dopamine secretion, regulation of synapse assembly, regulation of synaptic transmission, dopaminergic, response to cocaine, response to ethanol, response to hypoxia, response to nicotine, sensory perception of pain, sensory perception of sound, signal transduction, smooth muscle contraction, social behavior, synaptic transmission, synaptic transmission involved in micturition, synaptic transmission, cholinergic, vestibulocochlear nerve development, visual learning, visual perception acetylcholine-gated channel complex, cell junction, external side of plasma membrane, integral to membrane, plasma membrane, postsynaptic membrane acetylcholine binding, acetylcholine receptor activity, acetylcholine-activated cation-selective channel activity, ligand-gated ion channel activity Human CHRNB4 Reactome UniProtKB {GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_22438, GO:0007268=Reactome:REACT_13685, GO:0046928=PMID:11742001, GO:0006940=GO_REF:0000019, GO:0060084=PMID:11450844, GO:0007271=PMID:1330682, GO:0005892=PMID:11742001, GO:0006939=GO_REF:0000019, GO:0035095=GO_REF:0000019, GO:0007165=PMID:8906617, GO:0005887=PMID:11742001, GO:0015464=PMID:8906617, GO:0045211=GO_REF:0000039, GO:0007626=GO_REF:0000019, GO:0016021=PMID:8906617, GO:0001508=GO_REF:0000019, GO:0004889=PMID:11742001, GO:0015276=PMID:20438829, GO:0006811=PMID:8906617} P30926 Neuronal acetylcholine receptor subunit beta-4 protein 20100429 {GO:0005230=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0007268=TAS, GO:0046928=NAS, GO:0006940=IEA, GO:0060084=IMP, GO:0007271=TAS, GO:0005892=TAS, GO:0006939=IEA, GO:0035095=IEA, GO:0007165=IDA, GO:0005887=IC, GO:0015464=IDA, GO:0045211=IEA, GO:0007626=IEA, GO:0016021=NAS, GO:0001508=IEA, GO:0004889=TAS, GO:0015276=TAS, GO:0006811=TAS} behavioral response to nicotine, ion transport, locomotory behavior, regulation of action potential, regulation of neurotransmitter secretion, regulation of smooth muscle contraction, signal transduction, smooth muscle contraction, synaptic transmission, synaptic transmission involved in micturition, synaptic transmission, cholinergic acetylcholine-gated channel complex, cell junction, integral to membrane, integral to plasma membrane, plasma membrane, postsynaptic membrane acetylcholine receptor activity, acetylcholine-activated cation-selective channel activity, extracellular ligand-gated ion channel activity, ligand-gated ion channel activity Human CHRND BHF-UCL UniProtKB {GO:0048630=PMID:18252226, GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_22438, GO:0007268=Reactome:REACT_13685, GO:0005892=GO_REF:0000019, GO:0050905=PMID:18252226, GO:0007165=PMID:8872460, GO:0006936=PMID:8872460, GO:0050881=PMID:18252226, GO:0045211=PMID:18252226, GO:0042391=GO_REF:0000019, GO:0042166=GO_REF:0000019, GO:0006810=PMID:8872460, GO:0016021=GO_REF:0000038, GO:0004889=GO_REF:0000019, GO:0006811=GO_REF:0000002} Q07001 Acetylcholine receptor subunit delta protein 20080923 {GO:0048630=IMP, GO:0005230=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0007268=TAS, GO:0005892=IEA, GO:0050905=NAS, GO:0007165=TAS, GO:0006936=TAS, GO:0050881=IMP, GO:0045211=NAS, GO:0042391=IEA, GO:0042166=IEA, GO:0006810=TAS, GO:0016021=IEA, GO:0004889=IEA, GO:0006811=IEA} ion transport, muscle contraction, musculoskeletal movement, neuromuscular process, regulation of membrane potential, signal transduction, skeletal muscle tissue growth, synaptic transmission, transport acetylcholine-gated channel complex, cell junction, integral to membrane, plasma membrane, postsynaptic membrane acetylcholine binding, acetylcholine-activated cation-selective channel activity, extracellular ligand-gated ion channel activity Human CHRNE GOC UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_22438, GO:0008324=PMID:8872460, GO:0007268=Reactome:REACT_13685, GO:0005892=PMID:7531341, GO:0007271=PMID:8872460, GO:0007165=PMID:8872460, GO:0006936=PMID:8872460, GO:0005887=PMID:8872460, GO:0045211=GO_REF:0000039, GO:0015464=PMID:8872460, GO:0042391=GO_REF:0000019, GO:0006810=PMID:8872460, GO:0006812=PMID:8872460, GO:0004889=GO_REF:0000019} Q04844 Acetylcholine receptor subunit epsilon protein 20130413 {GO:0030054=IEA, GO:0005886=TAS, GO:0008324=TAS, GO:0007268=TAS, GO:0005892=TAS, GO:0007271=TAS, GO:0007165=TAS, GO:0006936=TAS, GO:0005887=TAS, GO:0045211=IEA, GO:0015464=TAS, GO:0042391=IEA, GO:0006810=TAS, GO:0006812=TAS, GO:0004889=IEA} cation transport, muscle contraction, regulation of membrane potential, signal transduction, synaptic transmission, synaptic transmission, cholinergic, transport acetylcholine-gated channel complex, cell junction, integral to plasma membrane, plasma membrane, postsynaptic membrane acetylcholine receptor activity, acetylcholine-activated cation-selective channel activity, cation transmembrane transporter activity Human CHRNG Reactome UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_22438, GO:0007268=Reactome:REACT_13685, GO:0005892=GO_REF:0000019, GO:0007165=PMID:3967651, GO:0006936=PMID:8040310, GO:0005887=PMID:3967651, GO:0045211=GO_REF:0000039, GO:0015464=PMID:3967651, GO:0042391=GO_REF:0000019, GO:0006810=PMID:3967651, GO:0016021=GO_REF:0000038, GO:0004889=GO_REF:0000019, GO:0015267=PMID:3967651} P07510 Acetylcholine receptor subunit gamma protein 20130301 {GO:0030054=IEA, GO:0005886=TAS, GO:0007268=TAS, GO:0005892=IEA, GO:0007165=TAS, GO:0006936=TAS, GO:0005887=TAS, GO:0045211=IEA, GO:0015464=TAS, GO:0042391=IEA, GO:0006810=TAS, GO:0016021=IEA, GO:0004889=IEA, GO:0015267=TAS} muscle contraction, regulation of membrane potential, signal transduction, synaptic transmission, transport acetylcholine-gated channel complex, cell junction, integral to membrane, integral to plasma membrane, plasma membrane, postsynaptic membrane acetylcholine receptor activity, acetylcholine-activated cation-selective channel activity, channel activity Human CHST1 Reactome UniProtKB {GO:0006790=PMID:10330415, GO:0005976=PMID:9405439, GO:0005975=Reactome:REACT_474, GO:0044281=Reactome:REACT_111217, GO:0042339=Reactome:REACT_121288, GO:0006954=GO_REF:0000037, GO:0045130=PMID:9405439, GO:0000139=Reactome:REACT_121317, GO:0018146=Reactome:REACT_121120, GO:0008146=PMID:10330415, GO:0016021=PMID:9405439, GO:0006012=PMID:10330415, GO:0030203=Reactome:REACT_121315} O43916 Carbohydrate sulfotransferase 1 protein 20130301 {GO:0006790=IDA, GO:0005976=TAS, GO:0005975=TAS, GO:0044281=TAS, GO:0042339=TAS, GO:0006954=IEA, GO:0045130=IDA, GO:0000139=TAS, GO:0018146=TAS, GO:0008146=IDA, GO:0016021=NAS, GO:0006012=IDA, GO:0030203=TAS} carbohydrate metabolic process, galactose metabolic process, glycosaminoglycan metabolic process, inflammatory response, keratan sulfate biosynthetic process, keratan sulfate metabolic process, polysaccharide metabolic process, small molecule metabolic process, sulfur compound metabolic process Golgi membrane, integral to membrane keratan sulfotransferase activity, sulfotransferase activity Human CHST10 PINC UniProtKB {GO:0016051=GO_REF:0000002, GO:0005794=PMID:9478973, GO:0016232=GO_REF:0000019, GO:0016020=PMID:9478973, GO:0000139=GO_REF:0000039, GO:0007616=GO_REF:0000019, GO:0008146=PMID:9478973, GO:0007612=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007155=PMID:9478973} O43529 Carbohydrate sulfotransferase 10 protein 20030904 {GO:0016051=IEA, GO:0005794=TAS, GO:0016232=IEA, GO:0016020=TAS, GO:0000139=IEA, GO:0007616=IEA, GO:0008146=TAS, GO:0007612=IEA, GO:0016021=IEA, GO:0007155=TAS} carbohydrate biosynthetic process, cell adhesion, learning, long-term memory Golgi apparatus, Golgi membrane, integral to membrane, membrane HNK-1 sulfotransferase activity, sulfotransferase activity Human CHST12 Reactome UniProtKB {GO:0005975=Reactome:REACT_474, GO:0044281=Reactome:REACT_111217, GO:0050656=PMID:10781601, GO:0016051=GO_REF:0000002, GO:0047756=PMID:10781601, GO:0030208=PMID:10781601, GO:0030206=Reactome:REACT_120989, GO:0030173=PMID:10781601, GO:0000139=Reactome:REACT_121270, GO:0008146=GO_REF:0000002, GO:0016021=GO_REF:0000002, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121315} Q9NRB3 Carbohydrate sulfotransferase 12 protein 20130301 {GO:0005975=TAS, GO:0044281=TAS, GO:0050656=NAS, GO:0016051=IEA, GO:0047756=IDA, GO:0030208=IDA, GO:0030206=TAS, GO:0030173=NAS, GO:0000139=TAS, GO:0008146=IEA, GO:0016021=IEA, GO:0030204=TAS, GO:0030203=TAS} carbohydrate biosynthetic process, carbohydrate metabolic process, chondroitin sulfate biosynthetic process, chondroitin sulfate metabolic process, dermatan sulfate biosynthetic process, glycosaminoglycan metabolic process, small molecule metabolic process Golgi membrane, integral to Golgi membrane, integral to membrane 3'-phosphoadenosine 5'-phosphosulfate binding, chondroitin 4-sulfotransferase activity, sulfotransferase activity Human CHST14 Reactome UniProtKB {GO:0030208=Reactome:REACT_120800, GO:0016051=GO_REF:0000002, GO:0000139=Reactome:REACT_120903, GO:0005975=Reactome:REACT_474, GO:0042301=PMID:11470797, GO:0008146=GO_REF:0000002, GO:0001537=PMID:11470797, GO:0044281=Reactome:REACT_111217, GO:0016021=PMID:11470797, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121315, GO:0050655=PMID:11470797} Q8NCH0 Carbohydrate sulfotransferase 14 protein 20130301 {GO:0030208=TAS, GO:0016051=IEA, GO:0000139=TAS, GO:0005975=TAS, GO:0042301=NAS, GO:0008146=IEA, GO:0001537=IDA, GO:0044281=TAS, GO:0016021=NAS, GO:0030204=TAS, GO:0030203=TAS, GO:0050655=IDA} carbohydrate biosynthetic process, carbohydrate metabolic process, chondroitin sulfate metabolic process, dermatan sulfate biosynthetic process, dermatan sulfate proteoglycan metabolic process, glycosaminoglycan metabolic process, small molecule metabolic process Golgi membrane, integral to membrane N-acetylgalactosamine 4-O-sulfotransferase activity, phosphate ion binding, sulfotransferase activity Human CHST15 Reactome UniProtKB {GO:0030206=Reactome:REACT_120989, GO:0000139=Reactome:REACT_120940, GO:0005975=Reactome:REACT_474, GO:0044281=Reactome:REACT_111217, GO:0019319=PMID:11572857, GO:0016021=PMID:11572857, GO:0050659=PMID:11572857, GO:0030204=Reactome:REACT_121206, GO:0050656=PMID:11572857, GO:0030203=Reactome:REACT_121315} Q7LFX5 Carbohydrate sulfotransferase 15 protein 20130301 {GO:0030206=TAS, GO:0000139=TAS, GO:0005975=TAS, GO:0044281=TAS, GO:0019319=IDA, GO:0016021=NAS, GO:0050659=IDA, GO:0030204=TAS, GO:0050656=IDA, GO:0030203=TAS} carbohydrate metabolic process, chondroitin sulfate biosynthetic process, chondroitin sulfate metabolic process, glycosaminoglycan metabolic process, hexose biosynthetic process, small molecule metabolic process Golgi membrane, integral to membrane 3'-phosphoadenosine 5'-phosphosulfate binding, N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity Human CHST3 Reactome UniProtKB {GO:0006790=PMID:9883891, GO:0030206=Reactome:REACT_120989, GO:0000139=Reactome:REACT_120725, GO:0005975=Reactome:REACT_474, GO:0050698=GO_REF:0000019, GO:0008146=PMID:9883891, GO:0008459=PMID:9883891, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0030204=Reactome:REACT_121206, GO:0043029=GO_REF:0000019, GO:0030203=Reactome:REACT_121315} Q7LGC8 Carbohydrate sulfotransferase 3 protein 20130301 {GO:0006790=IDA, GO:0030206=TAS, GO:0000139=TAS, GO:0005975=TAS, GO:0050698=IEA, GO:0008146=TAS, GO:0008459=IDA, GO:0044281=TAS, GO:0016021=IEA, GO:0030204=TAS, GO:0043029=IEA, GO:0030203=TAS} T cell homeostasis, carbohydrate metabolic process, chondroitin sulfate biosynthetic process, chondroitin sulfate metabolic process, glycosaminoglycan metabolic process, small molecule metabolic process, sulfur compound metabolic process Golgi membrane, integral to membrane chondroitin 6-sulfotransferase activity, proteoglycan sulfotransferase activity, sulfotransferase activity Human CHST4 PINC UniProtKB {GO:0005802=PMID:12855678, GO:0006790=PMID:10330415, GO:0005975=GO_REF:0000037, GO:0031228=PMID:12855678, GO:0006044=PMID:10330415, GO:0007267=PMID:10330415, GO:0006928=PMID:10330415, GO:0050901=GO_REF:0000019, GO:0006955=PMID:10330415, GO:0006954=GO_REF:0000037, GO:0008146=PMID:10330415, GO:0006477=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0001517=PMID:10330415, GO:0007155=PMID:10330415} Q8NCG5 Carbohydrate sulfotransferase 4 protein 20061107 {GO:0005802=IDA, GO:0006790=IDA, GO:0005975=IEA, GO:0031228=NAS, GO:0006044=IDA, GO:0007267=TAS, GO:0006928=TAS, GO:0050901=IEA, GO:0006955=TAS, GO:0006954=IEA, GO:0008146=TAS, GO:0006477=IEA, GO:0016021=IEA, GO:0001517=IDA, GO:0007155=TAS} N-acetylglucosamine metabolic process, carbohydrate metabolic process, cell adhesion, cell-cell signaling, cellular component movement, immune response, inflammatory response, leukocyte tethering or rolling, protein sulfation, sulfur compound metabolic process integral to membrane, intrinsic to Golgi membrane, trans-Golgi network N-acetylglucosamine 6-O-sulfotransferase activity, sulfotransferase activity Human CHST7 Reactome UniProtKB {GO:0006790=PMID:10913333, GO:0030206=Reactome:REACT_120989, GO:0000139=Reactome:REACT_120725, GO:0005976=PMID:10781596, GO:0005975=Reactome:REACT_474, GO:0006044=PMID:10913333, GO:0008459=PMID:10781596, GO:0044281=Reactome:REACT_111217, GO:0001517=PMID:10913333, GO:0016021=PMID:10913333, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121315} Q9NS84 Carbohydrate sulfotransferase 7 protein 20130301 {GO:0006790=IDA, GO:0030206=TAS, GO:0000139=TAS, GO:0005976=TAS, GO:0005975=TAS, GO:0006044=IDA, GO:0008459=IDA, GO:0044281=TAS, GO:0001517=IDA, GO:0016021=NAS, GO:0030204=TAS, GO:0030203=TAS} N-acetylglucosamine metabolic process, carbohydrate metabolic process, chondroitin sulfate biosynthetic process, chondroitin sulfate metabolic process, glycosaminoglycan metabolic process, polysaccharide metabolic process, small molecule metabolic process, sulfur compound metabolic process Golgi membrane, integral to membrane N-acetylglucosamine 6-O-sulfotransferase activity, chondroitin 6-sulfotransferase activity Human CHST9 Reactome UniProtKB {GO:0006790=PMID:11445554, GO:0005975=Reactome:REACT_474, GO:0005576=GO_REF:0000039, GO:0001537=PMID:11139592, GO:0044281=Reactome:REACT_111217, GO:0030166=GO_REF:0000024, GO:0016051=GO_REF:0000002, GO:0030206=Reactome:REACT_120989, GO:0000139=Reactome:REACT_121270, GO:0042446=GO_REF:0000024, GO:0016021=PMID:11139592, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121315} Q7L1S5 Carbohydrate sulfotransferase 9 protein 20130301 {GO:0006790=IDA, GO:0005975=TAS, GO:0005576=IEA, GO:0001537=IDA, GO:0044281=TAS, GO:0030166=ISS, GO:0016051=IEA, GO:0030206=TAS, GO:0000139=TAS, GO:0042446=ISS, GO:0016021=NAS, GO:0030204=TAS, GO:0030203=TAS} carbohydrate biosynthetic process, carbohydrate metabolic process, chondroitin sulfate biosynthetic process, chondroitin sulfate metabolic process, glycosaminoglycan metabolic process, hormone biosynthetic process, proteoglycan biosynthetic process, small molecule metabolic process, sulfur compound metabolic process Golgi membrane, extracellular region, integral to membrane N-acetylgalactosamine 4-O-sulfotransferase activity Human CHSY1 Reactome UniProtKB {GO:0005975=Reactome:REACT_474, GO:0005576=PMID:21129727, GO:0044281=Reactome:REACT_111217, GO:0050510=GO_REF:0000003, GO:0046872=GO_REF:0000037, GO:0030279=PMID:21129727, GO:0030206=Reactome:REACT_120989, GO:0000139=Reactome:REACT_121192, GO:0032580=GO_REF:0000039, GO:0031667=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0030204=Reactome:REACT_121206, GO:0047238=PMID:11514575, GO:0030203=Reactome:REACT_121315} Q86X52 Chondroitin sulfate synthase 1 protein 20130301 {GO:0005975=TAS, GO:0005576=IDA, GO:0044281=TAS, GO:0050510=IEA, GO:0046872=IEA, GO:0030279=IMP, GO:0030206=TAS, GO:0000139=TAS, GO:0032580=IEA, GO:0031667=IEA, GO:0016021=IEA, GO:0030204=TAS, GO:0047238=IDA, GO:0030203=TAS} carbohydrate metabolic process, chondroitin sulfate biosynthetic process, chondroitin sulfate metabolic process, glycosaminoglycan metabolic process, negative regulation of ossification, response to nutrient levels, small molecule metabolic process Golgi cisterna membrane, Golgi membrane, extracellular region, integral to membrane N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity, glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity, metal ion binding Human CHTF18 UniProtKB UniProtKB {GO:0006260=GO_REF:0000037, GO:0005737=GO_REF:0000019, GO:0007049=GO_REF:0000037, GO:0017111=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q8WVB6 Chromosome transmission fidelity protein 18 homolog protein 20130413 {GO:0006260=IEA, GO:0005737=IEA, GO:0007049=IEA, GO:0017111=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0005524=IEA} DNA replication, cell cycle cytoplasm, nucleus ATP binding, DNA binding, nucleoside-triphosphatase activity Human UniProtKB-SubCell:SL-0191 CHTF8 UniProtKB UniProtKB {GO:0006260=GO_REF:0000037, GO:0007049=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037} P0CG13 Chromosome transmission fidelity protein 8 homolog protein 20130413 {GO:0006260=IEA, GO:0007049=IEA, GO:0005634=IEA, GO:0003677=IEA} DNA replication, cell cycle nucleus DNA binding Human UniProtKB-SubCell:SL-0191 CHTOP HPA UniProtKB {GO:0005515=PMID:19858291, GO:0006355=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005654=GO_REF:0000039, GO:0006351=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q9Y3Y2 Chromatin target of PRMT1 protein protein 20101115 {GO:0005515=IPI, GO:0006355=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005654=IEA, GO:0006351=IEA, GO:0043231=IDA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular membrane-bounded organelle, nucleolus, nucleoplasm, nucleus RNA binding, protein binding Human CHUK BHF-UCL UniProtKB {GO:0005515=PMID:22810585, GO:0035631=GO_REF:0000024, GO:0007249=PMID:18626576, GO:0009653=PMID:10747982, GO:0043231=GO_REF:0000052, GO:0042802=PMID:21765415, GO:0002756=Reactome:REACT_6809, GO:0007173=Reactome:REACT_9417, GO:0002755=Reactome:REACT_27215, GO:0032496=GO_REF:0000019, GO:0043123=Reactome:REACT_24918, GO:0033194=GO_REF:0000019, GO:0038124=Reactome:REACT_8006, GO:0046982=GO_REF:0000019, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0009636=GO_REF:0000019, GO:0002224=Reactome:REACT_9020, GO:0033598=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0009898=GO_REF:0000024, GO:0034166=Reactome:REACT_9027, GO:0035666=Reactome:REACT_25281, GO:0051146=GO_REF:0000019, GO:0034162=Reactome:REACT_9047, GO:0050852=Reactome:REACT_12526, GO:0034142=Reactome:REACT_6894, GO:0008384=PMID:18626576, GO:0008385=PMID:18626576, GO:0070423=Reactome:REACT_75776, GO:0005634=GO_REF:0000052, GO:0007266=GO_REF:0000019, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_147740, GO:0005737=GO_REF:0000052, GO:0006955=PMID:9346484, GO:0006954=PMID:18626576, GO:0051092=Reactome:REACT_21281, GO:0042475=GO_REF:0000019, GO:0032481=Reactome:REACT_118823, GO:0043200=GO_REF:0000019, GO:0034138=Reactome:REACT_6783, GO:0048011=Reactome:REACT_11061, GO:0002011=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0007252=PMID:9252186, GO:0048015=Reactome:REACT_12464, GO:0005730=GO_REF:0000052, GO:0030316=GO_REF:0000019, GO:0009615=PMID:18626576, GO:0005524=GO_REF:0000037, GO:0004672=PMID:20434986, GO:0003009=GO_REF:0000019, GO:0007595=GO_REF:0000019, GO:0006468=PMID:20434986, GO:0034146=Reactome:REACT_9061, GO:0060749=GO_REF:0000019} O15111 Inhibitor of nuclear factor kappa-B kinase subunit alpha protein 20110110 {GO:0005515=IPI, GO:0035631=ISS, GO:0007249=TAS, GO:0009653=TAS, GO:0043231=IDA, GO:0042802=IPI, GO:0002756=TAS, GO:0007173=TAS, GO:0002755=TAS, GO:0032496=IEA, GO:0043123=TAS, GO:0033194=IEA, GO:0038124=TAS, GO:0046982=IEA, GO:0038123=TAS, GO:0034134=TAS, GO:0009636=IEA, GO:0002224=TAS, GO:0033598=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:0009898=ISS, GO:0034166=TAS, GO:0035666=TAS, GO:0051146=IEA, GO:0034162=TAS, GO:0050852=TAS, GO:0034142=TAS, GO:0008384=TAS, GO:0008385=TAS, GO:0070423=TAS, GO:0005634=IDA, GO:0007266=IEA, GO:0035872=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0006955=TAS, GO:0006954=TAS, GO:0051092=TAS, GO:0042475=IEA, GO:0032481=TAS, GO:0043200=IEA, GO:0034138=TAS, GO:0048011=TAS, GO:0002011=IEA, GO:0042493=IEA, GO:0007252=TAS, GO:0048015=TAS, GO:0005730=IDA, GO:0030316=IEA, GO:0009615=TAS, GO:0005524=IEA, GO:0004672=IDA, GO:0003009=IEA, GO:0007595=IEA, GO:0006468=IDA, GO:0034146=TAS, GO:0060749=IEA} I-kappaB kinase/NF-kappaB cascade, I-kappaB phosphorylation, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, Rho protein signal transduction, T cell receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, anatomical structure morphogenesis, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, immune response, inflammatory response, innate immune response, lactation, mammary gland alveolus development, mammary gland epithelial cell proliferation, morphogenesis of an epithelial sheet, neurotrophin TRK receptor signaling pathway, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, nucleotide-binding oligomerization domain containing signaling pathway, odontogenesis of dentin-containing tooth, osteoclast differentiation, phosphatidylinositol-mediated signaling, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of type I interferon production, protein phosphorylation, response to amino acid stimulus, response to drug, response to hydroperoxide, response to lipopolysaccharide, response to toxic substance, response to virus, skeletal muscle contraction, striated muscle cell differentiation, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway CD40 receptor complex, IkappaB kinase complex, cytoplasm, cytosol, internal side of plasma membrane, intracellular membrane-bounded organelle, nucleolus, nucleus ATP binding, IkappaB kinase activity, identical protein binding, protein binding, protein heterodimerization activity, protein kinase activity Human UniProtKB:Q60680 CHURC1 UniProtKB UniProtKB {GO:0008270=GO_REF:0000002, GO:0007275=GO_REF:0000037, GO:0045893=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q8WUH1 Protein Churchill protein 20130413 {GO:0008270=IEA, GO:0007275=IEA, GO:0045893=IEA, GO:0006351=IEA} multicellular organismal development, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent zinc ion binding Human UniProtKB-KW:KW-0217 CIAO1 Reactome UniProtKB {GO:0008284=PMID:9556563, GO:0007059=GO_REF:0000037, GO:0006357=PMID:9556563, GO:0016226=PMID:17937914, GO:0097361=PMID:22678361, GO:0044281=Reactome:REACT_111217, GO:0071817=PMID:20797633} O76071 Probable cytosolic iron-sulfur protein assembly protein CIAO1 protein 20120307 {GO:0008284=TAS, GO:0007059=IEA, GO:0006357=TAS, GO:0016226=IGI, GO:0097361=IDA, GO:0044281=TAS, GO:0071817=IDA} chromosome segregation, iron-sulfur cluster assembly, positive regulation of cell proliferation, regulation of transcription from RNA polymerase II promoter, small molecule metabolic process CIA complex, MMXD complex Human CIAPIN1 HPA UniProtKB {GO:0030097=GO_REF:0000019, GO:0043066=PMID:14970183, GO:0005737=PMID:16957168, GO:0051536=GO_REF:0000002, GO:0016226=GO_REF:0000002, GO:0008168=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217} Q6FI81 Anamorsin protein 20110516 {GO:0030097=IEA, GO:0043066=ISS, GO:0005737=IDA, GO:0051536=IEA, GO:0016226=IEA, GO:0008168=IEA, GO:0005730=IDA, GO:0006915=IEA, GO:0005634=IDA, GO:0044281=TAS} apoptotic process, hemopoiesis, iron-sulfur cluster assembly, negative regulation of apoptotic process, small molecule metabolic process cytoplasm, nucleolus, nucleus iron-sulfur cluster binding, methyltransferase activity NOT Human CIB1 BHF-UCL UniProtKB {GO:0005515=PMID:20639889, GO:0008285=PMID:21264284, GO:0005783=PMID:10366599, GO:0005509=PMID:15475008, GO:0006915=PMID:10366599, GO:0030175=GO_REF:0000039, GO:0006974=PMID:12011095, GO:0006302=PMID:9372844, GO:0042383=PMID:20639889, GO:0016324=GO_REF:0000039, GO:0005737=PMID:20639889, GO:0016020=PMID:10366599, GO:0007113=PMID:21264284, GO:0005654=PMID:10366599, GO:0043495=PMID:20639889, GO:0007155=PMID:9030514, GO:0090004=PMID:20639889} Q99828 Calcium and integrin-binding protein 1 protein 20121209 {GO:0005515=IPI, GO:0008285=IMP, GO:0005783=IMP, GO:0005509=IMP, GO:0006915=IMP, GO:0030175=IEA, GO:0006974=IDA, GO:0006302=TAS, GO:0042383=IDA, GO:0016324=IEA, GO:0005737=IDA, GO:0016020=IDA, GO:0007113=IDA, GO:0005654=IMP, GO:0043495=IGI, GO:0007155=TAS, GO:0090004=IGI} apoptotic process, cell adhesion, double-strand break repair, endomitotic cell cycle, negative regulation of cell proliferation, positive regulation of establishment of protein localization to plasma membrane, response to DNA damage stimulus apical plasma membrane, cytoplasm, endoplasmic reticulum, filopodium, membrane, nucleoplasm, sarcolemma calcium ion binding, protein anchor, protein binding Human UniProtKB:Q63810-2 CIB2 UniProtKB UniProtKB {GO:0005515=PMID:23023331, GO:0001917=GO_REF:0000024, GO:0007229=GO_REF:0000038, GO:0005509=GO_REF:0000002, GO:0045494=GO_REF:0000024, GO:0055074=GO_REF:0000024} Q05BT6 CIB2 protein protein 20130413 {GO:0005515=IPI, GO:0001917=ISS, GO:0007229=IEA, GO:0005509=IEA, GO:0045494=ISS, GO:0055074=ISS} calcium ion homeostasis, integrin-mediated signaling pathway, photoreceptor cell maintenance photoreceptor inner segment calcium ion binding, protein binding Human UniProtKB-KW:KW-0401 CIC IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96RK0 Protein capicua homolog protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, protein binding Human UniProtKB:Q9HC77 CIDEA BHF-UCL UniProtKB {GO:0006629=GO_REF:0000024, GO:0005811=PMID:18509062, GO:0008219=PMID:17080483, GO:0006355=GO_REF:0000037, GO:0035634=GO_REF:0000019, GO:0043066=PMID:17080483, GO:0001659=GO_REF:0000024, GO:0050995=GO_REF:0000024, GO:0008630=PMID:9564035, GO:0019915=GO_REF:0000024, GO:0006915=PMID:9564035, GO:0032720=PMID:15919794, GO:0005634=PMID:17080483, GO:0005740=GO_REF:0000024, GO:0050710=PMID:15919794, GO:0006351=GO_REF:0000037, GO:0042803=PMID:17080483, GO:0005739=GO_REF:0000024, GO:0005737=PMID:17080483, GO:0006309=PMID:9564035, GO:0010890=PMID:18509062, GO:0030512=PMID:17080483} O60543 Cell death activator CIDE-A protein 20121007 {GO:0006629=ISS, GO:0005811=IDA, GO:0008219=ISS, GO:0006355=IEA, GO:0035634=IEA, GO:0043066=ISS, GO:0001659=ISS, GO:0050995=ISS, GO:0008630=TAS, GO:0019915=ISS, GO:0006915=ISS, GO:0032720=IMP, GO:0005634=ISS, GO:0005740=ISS, GO:0050710=IMP, GO:0006351=IEA, GO:0042803=ISS, GO:0005739=ISS, GO:0005737=ISS, GO:0006309=ISS, GO:0010890=ISS, GO:0030512=ISS} apoptotic DNA fragmentation, apoptotic process, cell death, intrinsic apoptotic signaling pathway in response to DNA damage, lipid metabolic process, lipid storage, negative regulation of apoptotic process, negative regulation of cytokine secretion, negative regulation of lipid catabolic process, negative regulation of transforming growth factor beta receptor signaling pathway, negative regulation of tumor necrosis factor production, positive regulation of sequestering of triglyceride, regulation of transcription, DNA-dependent, response to stilbenoid, temperature homeostasis, transcription, DNA-dependent cytoplasm, lipid particle, mitochondrial envelope, mitochondrion, nucleus protein homodimerization activity Human UniProtKB:O70302 CIDEB MGI UniProtKB {GO:0008630=PMID:10619428, GO:0006917=PMID:12429024, GO:0005829=PMID:12429024} Q9UHD4 Cell death activator CIDE-B protein 20040116 {GO:0008630=TAS, GO:0006917=IDA, GO:0005829=IDA} induction of apoptosis, intrinsic apoptotic signaling pathway in response to DNA damage cytosol Human CIDEC HPA UniProtKB {GO:0005811=GO_REF:0000039, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0005783=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0006917=PMID:12429024, GO:0005925=GO_REF:0000052, GO:0006351=GO_REF:0000037, GO:0005829=PMID:12429024} Q96AQ7 Cell death activator CIDE-3 protein 20100326 {GO:0005811=IEA, GO:0003674=ND, GO:0005737=IDA, GO:0006355=IEA, GO:0005783=IEA, GO:0006915=IEA, GO:0005634=IDA, GO:0006917=IDA, GO:0005925=IDA, GO:0006351=IEA, GO:0005829=IDA} apoptotic process, induction of apoptosis, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, cytosol, endoplasmic reticulum, focal adhesion, lipid particle, nucleus molecular_function Human CIITA BHF-UCL UniProtKB {GO:0005515=PMID:21890893, GO:0006355=GO_REF:0000002, GO:0044212=PMID:19041327, GO:0019221=Reactome:REACT_25229, GO:0003713=PMID:7749984, GO:0000122=PMID:19041327, GO:0008022=PMID:16600381, GO:0005524=GO_REF:0000037, GO:0003677=PMID:15771576, GO:0032403=PMID:17493635, GO:0006351=GO_REF:0000037, GO:0045348=PMID:9171108, GO:0006955=PMID:8402893, GO:0045345=PMID:20639463, GO:0032966=PMID:19041327, GO:0045944=PMID:20639463, GO:0016605=PMID:23007646, GO:0005654=Reactome:REACT_25082, GO:0034341=PMID:19041327, GO:0045893=PMID:19041327, GO:0033613=PMID:9171108, GO:0045892=PMID:19041327, GO:0046677=PMID:107465, GO:0060333=Reactome:REACT_25078} P33076 MHC class II transactivator protein 20110309 {GO:0005515=IPI, GO:0006355=IEA, GO:0044212=IDA, GO:0019221=TAS, GO:0003713=TAS, GO:0000122=IMP, GO:0008022=IPI, GO:0005524=IEA, GO:0003677=TAS, GO:0032403=IDA, GO:0006351=IEA, GO:0045348=IC, GO:0006955=TAS, GO:0045345=IDA, GO:0032966=IC, GO:0045944=IDA, GO:0016605=IDA, GO:0005654=TAS, GO:0034341=IDA, GO:0045893=IDA, GO:0033613=IPI, GO:0045892=IDA, GO:0046677=IDA, GO:0060333=TAS} cytokine-mediated signaling pathway, immune response, interferon-gamma-mediated signaling pathway, negative regulation of collagen biosynthetic process, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of MHC class I biosynthetic process, positive regulation of MHC class II biosynthetic process, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, response to antibiotic, response to interferon-gamma, transcription, DNA-dependent PML body, nucleoplasm ATP binding, DNA binding, activating transcription factor binding, protein C-terminus binding, protein binding, protein complex binding, transcription coactivator activity, transcription regulatory region DNA binding Human CINP UniProtKB UniProtKB {GO:0005515=PMID:21131973, GO:0006260=GO_REF:0000037, GO:0007049=GO_REF:0000037, GO:0006281=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0051301=GO_REF:0000037} Q9BW66 Cyclin-dependent kinase 2-interacting protein protein 20110502 {GO:0005515=IPI, GO:0006260=IEA, GO:0007049=IEA, GO:0006281=IEA, GO:0005634=IEA, GO:0051301=IEA} DNA repair, DNA replication, cell cycle, cell division nucleus protein binding Human UniProtKB:O94986 CIR1 BHF-UCL UniProtKB {GO:0005515=PMID:15652350, GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0005737=GO_REF:0000037, GO:0003700=PMID:9874765, GO:0000118=PMID:9874765, GO:0016607=GO_REF:0000039, GO:0005815=GO_REF:0000039, GO:0003705=PMID:18663143, GO:0003714=PMID:9874765, GO:0005634=PMID:9874765, GO:0045892=PMID:9874765} Q86X95 Corepressor interacting with RBPJ 1 protein 20120925 {GO:0005515=IPI, GO:0008380=IEA, GO:0006397=IEA, GO:0005737=IEA, GO:0003700=TAS, GO:0000118=IDA, GO:0016607=IEA, GO:0005815=IEA, GO:0003705=TAS, GO:0003714=TAS, GO:0005634=IDA, GO:0045892=IDA} RNA splicing, mRNA processing, negative regulation of transcription, DNA-dependent cytoplasm, histone deacetylase complex, microtubule organizing center, nuclear speck, nucleus RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, protein binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human CIRBP GOC UniProtKB {GO:0017148=GO_REF:0000024, GO:0005515=PMID:16513844, GO:0010494=GO_REF:0000024, GO:0009409=PMID:9151692, GO:0045727=PMID:11574538, GO:0005634=PMID:11574538, GO:0030371=GO_REF:0000024, GO:0003676=GO_REF:0000002, GO:0005737=GO_REF:0000024, GO:0034063=GO_REF:0000024, GO:0000166=GO_REF:0000002, GO:0070181=PMID:11574538, GO:0005654=GO_REF:0000039, GO:0048255=PMID:11574538, GO:0003730=PMID:16513844, GO:0009411=PMID:11574538} Q14011 Cold-inducible RNA-binding protein protein 20130413 {GO:0017148=ISS, GO:0005515=IPI, GO:0010494=ISS, GO:0009409=TAS, GO:0045727=IDA, GO:0005634=IDA, GO:0030371=ISS, GO:0003676=IEA, GO:0005737=ISS, GO:0034063=ISS, GO:0000166=IEA, GO:0070181=IDA, GO:0005654=IEA, GO:0048255=IDA, GO:0003730=IDA, GO:0009411=IDA} mRNA stabilization, negative regulation of translation, positive regulation of translation, response to UV, response to cold, stress granule assembly cytoplasm, cytoplasmic stress granule, nucleoplasm, nucleus SSU rRNA binding, mRNA 3'-UTR binding, nucleic acid binding, nucleotide binding, protein binding, translation repressor activity Human UniProtKB:P60824 CIRH1A UniProtKB UniProtKB {GO:0005515=PMID:19732766, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0006355=PMID:19732766, GO:0005730=PMID:16225863, GO:0006351=GO_REF:0000037} Q969X6 Cirhin protein 20120620 {GO:0005515=IPI, GO:0003674=ND, GO:0008150=ND, GO:0006355=IDA, GO:0005730=IDA, GO:0006351=IEA} biological_process, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus molecular_function, protein binding Human UniProtKB:P15822 CISD1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000024, GO:0051537=GO_REF:0000037, GO:0005741=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0043457=GO_REF:0000019, GO:0046872=GO_REF:0000037} Q9NZ45 CDGSH iron-sulfur domain-containing protein 1 protein 20041006 {GO:0005739=ISS, GO:0051537=IEA, GO:0005741=IEA, GO:0016021=IEA, GO:0043457=IEA, GO:0046872=IEA} regulation of cellular respiration integral to membrane, mitochondrial outer membrane, mitochondrion 2 iron, 2 sulfur cluster binding, metal ion binding Human UniProtKB:Q91WS0 CISD2 HPA UniProtKB {GO:0005515=PMID:20010695, GO:0000422=GO_REF:0000019, GO:0051537=PMID:19580816, GO:0005783=GO_REF:0000052, GO:0010259=GO_REF:0000024, GO:0005741=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0042803=PMID:19580816, GO:0043231=GO_REF:0000002, GO:0043234=GO_REF:0000054, GO:0005789=PMID:20010695, GO:0010506=PMID:20010695, GO:0016021=GO_REF:0000037} Q8N5K1 CDGSH iron-sulfur domain-containing protein 2 protein 20090616 {GO:0005515=IPI, GO:0000422=IEA, GO:0051537=IDA, GO:0005783=IDA, GO:0010259=ISS, GO:0005741=ISS, GO:0046872=IEA, GO:0042803=IDA, GO:0043231=IEA, GO:0043234=IDA, GO:0005789=IDA, GO:0010506=IMP, GO:0016021=IEA} mitochondrion degradation, multicellular organismal aging, regulation of autophagy endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle, mitochondrial outer membrane, protein complex 2 iron, 2 sulfur cluster binding, metal ion binding, protein binding, protein homodimerization activity Human CISH Reactome UniProtKB {GO:0035556=PMID:10902923, GO:0003674=GO_REF:0000015, GO:0016567=GO_REF:0000041, GO:0005886=GO_REF:0000019, GO:0060397=Reactome:REACT_111133, GO:0005575=GO_REF:0000015, GO:0009968=GO_REF:0000037, GO:0001558=PMID:9465889, GO:0007205=GO_REF:0000019, GO:0005829=Reactome:REACT_111181} Q9NSE2 Cytokine-inducible SH2-containing protein protein 20130301 {GO:0035556=NAS, GO:0003674=ND, GO:0016567=IEA, GO:0005886=IEA, GO:0060397=TAS, GO:0005575=ND, GO:0009968=IEA, GO:0001558=NAS, GO:0007205=IEA, GO:0005829=TAS} JAK-STAT cascade involved in growth hormone signaling pathway, intracellular signal transduction, negative regulation of signal transduction, protein kinase C-activating G-protein coupled receptor signaling pathway, protein ubiquitination, regulation of cell growth cellular_component, cytosol, plasma membrane molecular_function Human CIT UniProtKB UniProtKB {GO:0005773=GO_REF:0000019, GO:0017124=GO_REF:0000037, GO:0048699=PMID:11086988, GO:0007283=GO_REF:0000019, GO:0015629=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0001726=GO_REF:0000019, GO:0016358=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0035556=GO_REF:0000002, GO:0007067=PMID:11086988, GO:0005083=GO_REF:0000002, GO:0000070=GO_REF:0000019, GO:0004672=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0004674=PMID:9792683, GO:0050774=GO_REF:0000019, GO:0007091=GO_REF:0000019} O14578 Citron Rho-interacting kinase protein 20051020 {GO:0005773=IEA, GO:0017124=IEA, GO:0048699=ISS, GO:0007283=IEA, GO:0015629=IEA, GO:0005524=IEA, GO:0001726=IEA, GO:0016358=IEA, GO:0046872=IEA, GO:0035556=IEA, GO:0007067=ISS, GO:0005083=IEA, GO:0000070=IEA, GO:0004672=IEA, GO:0005543=IEA, GO:0004674=ISS, GO:0050774=IEA, GO:0007091=IEA} dendrite development, generation of neurons, intracellular signal transduction, metaphase/anaphase transition of mitotic cell cycle, mitosis, mitotic sister chromatid segregation, negative regulation of dendrite morphogenesis, spermatogenesis actin cytoskeleton, ruffle, vacuole ATP binding, SH3 domain binding, metal ion binding, phospholipid binding, protein kinase activity, protein serine/threonine kinase activity, small GTPase regulator activity Human UniProtKB:P49025 CITED1 BHF-UCL UniProtKB {GO:0001656=PMID:17336183, GO:0005515=PMID:11581164, GO:0060711=GO_REF:0000019, GO:0001658=GO_REF:0000024, GO:0043627=PMID:17938205, GO:0003700=PMID:8901575, GO:0044212=PMID:11581164, GO:0060712=GO_REF:0000019, GO:0051591=GO_REF:0000024, GO:0042803=PMID:21172805, GO:0043524=PMID:21172805, GO:0000578=GO_REF:0000019, GO:0042438=GO_REF:0000024, GO:0070670=GO_REF:0000024, GO:0032496=GO_REF:0000024, GO:0007179=PMID:9707553, GO:0032868=GO_REF:0000024, GO:0071107=GO_REF:0000024, GO:0071104=GO_REF:0000024, GO:0071105=GO_REF:0000024, GO:0003713=PMID:9707553, GO:0060231=PMID:17336183, GO:0001890=GO_REF:0000024, GO:0007420=GO_REF:0000019, GO:0070741=GO_REF:0000024, GO:0045893=PMID:9707553, GO:0045892=PMID:11581164, GO:0008283=PMID:17336183, GO:0030178=PMID:17336183, GO:0005634=PMID:9434189, GO:0060395=PMID:9707553, GO:0005829=PMID:16864582, GO:0005737=PMID:17710162, GO:0034341=GO_REF:0000024, GO:0034097=GO_REF:0000024, GO:0070555=GO_REF:0000024, GO:0071559=PMID:9707553, GO:0030511=PMID:17336183, GO:0006355=GO_REF:0000002, GO:0006357=PMID:9434189, GO:0070410=PMID:9707553, GO:0006915=GO_REF:0000037, GO:0030318=PMID:8901575, GO:0003340=GO_REF:0000019, GO:0008022=PMID:15843474, GO:0050693=PMID:11581164, GO:0006351=GO_REF:0000037, GO:0006913=PMID:16864582, GO:0010628=GO_REF:0000024, GO:0045668=GO_REF:0000024, GO:0003682=GO_REF:0000024, GO:0043473=PMID:8901575, GO:0001570=GO_REF:0000019, GO:0070669=GO_REF:0000024} Q99966 Cbp/p300-interacting transactivator 1 protein 20080923 {GO:0001656=TAS, GO:0005515=IPI, GO:0060711=IEA, GO:0001658=ISS, GO:0043627=TAS, GO:0003700=NAS, GO:0044212=IDA, GO:0060712=IEA, GO:0051591=ISS, GO:0042803=IDA, GO:0043524=IDA, GO:0000578=IEA, GO:0042438=ISS, GO:0070670=ISS, GO:0032496=ISS, GO:0007179=IDA, GO:0032868=ISS, GO:0071107=ISS, GO:0071104=ISS, GO:0071105=ISS, GO:0003713=IDA, GO:0060231=TAS, GO:0001890=ISS, GO:0007420=IEA, GO:0070741=ISS, GO:0045893=IDA, GO:0045892=IDA, GO:0008283=TAS, GO:0030178=TAS, GO:0005634=IDA, GO:0060395=IDA, GO:0005829=IDA, GO:0005737=IDA, GO:0034341=ISS, GO:0034097=ISS, GO:0070555=ISS, GO:0071559=IDA, GO:0030511=TAS, GO:0006355=IEA, GO:0006357=TAS, GO:0070410=IPI, GO:0006915=IEA, GO:0030318=IMP, GO:0003340=IEA, GO:0008022=IPI, GO:0050693=IDA, GO:0006351=IEA, GO:0006913=IDA, GO:0010628=ISS, GO:0045668=ISS, GO:0003682=ISS, GO:0043473=IMP, GO:0001570=IEA, GO:0070669=ISS} SMAD protein signal transduction, apoptotic process, brain development, branching involved in ureteric bud morphogenesis, cell proliferation, embryonic axis specification, labyrinthine layer development, melanin biosynthetic process, melanocyte differentiation, mesenchymal to epithelial transition, metanephros development, negative regulation of Wnt receptor signaling pathway, negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis, negative regulation of neuron apoptotic process, negative regulation of osteoblast differentiation, negative regulation of transcription, DNA-dependent, nucleocytoplasmic transport, pigmentation, placenta development, positive regulation of gene expression, positive regulation of transcription, DNA-dependent, positive regulation of transforming growth factor beta receptor signaling pathway, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, response to cAMP, response to cytokine stimulus, response to estrogen stimulus, response to insulin stimulus, response to interferon-gamma, response to interleukin-1, response to interleukin-11, response to interleukin-2, response to interleukin-4, response to interleukin-6, response to interleukin-9, response to lipopolysaccharide, response to parathyroid hormone stimulus, response to transforming growth factor beta stimulus, spongiotrophoblast layer development, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, vasculogenesis cytoplasm, cytosol, nucleus LBD domain binding, chromatin binding, co-SMAD binding, protein C-terminus binding, protein binding, protein homodimerization activity, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, transcription regulatory region DNA binding Human CITED2 BHF-UCL UniProtKB {GO:0005515=PMID:12586840, GO:0000790=GO_REF:0000024, GO:0043627=PMID:11581164, GO:0003700=GO_REF:0000024, GO:0034405=PMID:12960175, GO:0048538=GO_REF:0000019, GO:0046332=GO_REF:0000019, GO:0048536=GO_REF:0000024, GO:0048596=GO_REF:0000019, GO:0001947=GO_REF:0000019, GO:0007507=GO_REF:0000024, GO:1900164=GO_REF:0000024, GO:0007179=GO_REF:0000019, GO:0035802=GO_REF:0000024, GO:0035035=PMID:22735262, GO:0001102=GO_REF:0000019, GO:0030336=PMID:18054336, GO:0001105=GO_REF:0000019, GO:0022409=GO_REF:0000024, GO:0001106=PMID:22735262, GO:0007569=GO_REF:0000019, GO:0003714=PMID:17906695, GO:0003713=PMID:22735262, GO:0060136=GO_REF:0000019, GO:0001843=GO_REF:0000019, GO:0001892=GO_REF:0000019, GO:0000122=PMID:17906695, GO:0061428=PMID:22735262, GO:0007417=GO_REF:0000019, GO:0045787=GO_REF:0000024, GO:0001889=GO_REF:0000024, GO:0061156=GO_REF:0000019, GO:0060349=GO_REF:0000019, GO:0007422=GO_REF:0000019, GO:0045893=PMID:9434189, GO:0045892=PMID:15051727, GO:0007368=GO_REF:0000024, GO:0008283=PMID:15051727, GO:0005634=PMID:22735262, GO:0070986=GO_REF:0000024, GO:0007530=GO_REF:0000024, GO:0046697=GO_REF:0000019, GO:0035360=PMID:15051727, GO:0002089=GO_REF:0000019, GO:0002244=GO_REF:0000019, GO:0045944=PMID:22735262, GO:0048821=GO_REF:0000019, GO:0060971=GO_REF:0000024, GO:0030851=GO_REF:0000019, GO:0021602=GO_REF:0000019, GO:0030511=GO_REF:0000024, GO:0001666=PMID:17906695, GO:0043066=GO_REF:0000024, GO:0003197=GO_REF:0000019, GO:0060412=GO_REF:0000024, GO:0003156=GO_REF:0000024, GO:0050693=PMID:15051727, GO:0001829=GO_REF:0000019, GO:0003151=GO_REF:0000024, GO:0009612=GO_REF:0000019, GO:0010628=PMID:15051727, GO:0003682=GO_REF:0000024, GO:0061308=GO_REF:0000019, GO:0010629=PMID:15051727, GO:0001570=GO_REF:0000019, GO:0008584=GO_REF:0000019, GO:2000020=GO_REF:0000024} Q99967 Cbp/p300-interacting transactivator 2 protein 20120517 {GO:0005515=IPI, GO:0000790=ISS, GO:0043627=IDA, GO:0003700=ISS, GO:0034405=IMP, GO:0048538=IEA, GO:0046332=IEA, GO:0048536=ISS, GO:0048596=IEA, GO:0001947=IEA, GO:0007507=ISS, GO:1900164=ISS, GO:0007179=IEA, GO:0035802=ISS, GO:0035035=IDA, GO:0001102=IEA, GO:0030336=IMP, GO:0001105=IEA, GO:0022409=ISS, GO:0001106=IDA, GO:0007569=IEA, GO:0003714=IMP, GO:0003713=IDA, GO:0060136=IEA, GO:0001843=IEA, GO:0001892=IEA, GO:0000122=IMP, GO:0061428=IDA, GO:0007417=IEA, GO:0045787=ISS, GO:0001889=ISS, GO:0061156=IEA, GO:0060349=IEA, GO:0007422=IEA, GO:0045893=IDA, GO:0045892=IDA, GO:0007368=ISS, GO:0008283=IDA, GO:0005634=IDA, GO:0070986=ISS, GO:0007530=ISS, GO:0046697=IEA, GO:0035360=IDA, GO:0002089=IEA, GO:0002244=IEA, GO:0045944=IDA, GO:0048821=IEA, GO:0060971=ISS, GO:0030851=IEA, GO:0021602=IEA, GO:0030511=ISS, GO:0001666=IMP, GO:0043066=ISS, GO:0003197=IEA, GO:0060412=ISS, GO:0003156=ISS, GO:0050693=IPI, GO:0001829=IEA, GO:0003151=ISS, GO:0009612=IEA, GO:0010628=IDA, GO:0003682=ISS, GO:0061308=IEA, GO:0010629=IDA, GO:0001570=IEA, GO:0008584=IEA, GO:2000020=ISS} adrenal cortex formation, bone morphogenesis, cardiac neural crest cell development involved in heart development, cell aging, cell proliferation, central nervous system development, cranial nerve morphogenesis, decidualization, determination of left/right symmetry, embryonic camera-type eye morphogenesis, embryonic heart tube left/right pattern formation, embryonic placenta development, embryonic process involved in female pregnancy, endocardial cushion development, erythrocyte development, granulocyte differentiation, heart development, heart looping, hematopoietic progenitor cell differentiation, left/right axis specification, lens morphogenesis in camera-type eye, liver development, male gonad development, negative regulation of apoptotic process, negative regulation of cell migration, negative regulation of gene expression, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription from RNA polymerase II promoter in response to hypoxia, negative regulation of transcription, DNA-dependent, neural tube closure, nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry, outflow tract morphogenesis, peripheral nervous system development, positive regulation of cell cycle, positive regulation of cell-cell adhesion, positive regulation of gene expression, positive regulation of male gonad development, positive regulation of peroxisome proliferator activated receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of transforming growth factor beta receptor signaling pathway, pulmonary artery morphogenesis, regulation of organ formation, response to estrogen stimulus, response to fluid shear stress, response to hypoxia, response to mechanical stimulus, sex determination, spleen development, thymus development, transforming growth factor beta receptor signaling pathway, trophectodermal cell differentiation, vasculogenesis, ventricular septum morphogenesis nuclear chromatin, nucleus LBD domain binding, RNA polymerase II activating transcription factor binding, RNA polymerase II transcription coactivator activity, RNA polymerase II transcription corepressor activity, SMAD binding, chromatin binding, histone acetyltransferase binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, transcription corepressor activity Human UniProtKB:O35740 CITED4 UniProtKB UniProtKB {GO:0043627=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0003713=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0045893=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q96RK1 Cbp/p300-interacting transactivator 4 protein 20110420 {GO:0043627=ISS, GO:0005737=IEA, GO:0003713=ISS, GO:0005634=IEA, GO:0045893=IEA, GO:0006351=IEA} positive regulation of transcription, DNA-dependent, response to estrogen stimulus, transcription, DNA-dependent cytoplasm, nucleus transcription coactivator activity Human UniProtKB:Q9WUL8 CIZ1 IntAct UniProtKB {GO:0005515=PMID:18654987, GO:0032298=GO_REF:0000019, GO:0030332=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0051658=GO_REF:0000019} Q9ULV3 Cip1-interacting zinc finger protein protein 20130415 {GO:0005515=IPI, GO:0032298=IEA, GO:0030332=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0051658=IEA} maintenance of nucleus location, positive regulation of DNA-dependent DNA replication initiation nucleus cyclin binding, nucleic acid binding, protein binding, zinc ion binding Human UniProtKB:Q9P0V3 CKAP2 HPA UniProtKB {GO:0005881=PMID:16061649, GO:0005813=PMID:21399614, GO:0000922=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0000281=PMID:16061649, GO:0045944=PMID:16061649, GO:0015630=GO_REF:0000052, GO:0007026=GO_REF:0000019, GO:0006915=GO_REF:0000037} Q8WWK9 Cytoskeleton-associated protein 2 protein 20101115 {GO:0005881=IDA, GO:0005813=IDA, GO:0000922=IEA, GO:0005737=IDA, GO:0000281=IGI, GO:0045944=IGI, GO:0015630=IDA, GO:0007026=IEA, GO:0006915=IEA} apoptotic process, cytokinesis after mitosis, negative regulation of microtubule depolymerization, positive regulation of transcription from RNA polymerase II promoter centrosome, cytoplasm, cytoplasmic microtubule, microtubule cytoskeleton, spindle pole Human CKAP2L UniProtKB UniProtKB {GO:0005813=PMID:21399614} Q8IYA6 Cytoskeleton-associated protein 2-like protein 20110517 {GO:0005813=IDA} centrosome Human CKAP4 PINC UniProtKB {GO:0048471=GO_REF:0000039, GO:0016020=PMID:8314870, GO:0005886=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0005856=GO_REF:0000039} Q07065 Cytoskeleton-associated protein 4 protein 20030904 {GO:0048471=IEA, GO:0016020=TAS, GO:0005886=IEA, GO:0005789=IEA, GO:0016021=IEA, GO:0005856=IEA} cytoskeleton, endoplasmic reticulum membrane, integral to membrane, membrane, perinuclear region of cytoplasm, plasma membrane Human CKAP5 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0000236=Reactome:REACT_682, GO:0005813=PMID:14718566, GO:0030951=PMID:14718566, GO:0035371=PMID:21646404, GO:0050658=PMID:15703215, GO:0005829=Reactome:REACT_150414, GO:0051297=PMID:14718566, GO:0043234=PMID:18468998, GO:0000922=PMID:21646404, GO:0000086=Reactome:REACT_2203, GO:0000087=Reactome:REACT_910, GO:0015630=PMID:15703215, GO:0000930=PMID:14718566, GO:0007051=PMID:14718566, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q14008 Cytoskeleton-associated protein 5 protein 20130415 {GO:0005515=IPI, GO:0000236=TAS, GO:0005813=IDA, GO:0030951=IMP, GO:0035371=IDA, GO:0050658=ISS, GO:0005829=TAS, GO:0051297=IMP, GO:0043234=IDA, GO:0000922=IDA, GO:0000086=TAS, GO:0000087=TAS, GO:0015630=ISS, GO:0000930=IDA, GO:0007051=IMP, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA transport, cell division, centrosome organization, establishment or maintenance of microtubule cytoskeleton polarity, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, spindle organization centrosome, cytosol, gamma-tubulin complex, microtubule cytoskeleton, microtubule plus end, protein complex, spindle pole protein binding Human UniProtKB:P16333 CKB IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0004111=GO_REF:0000003, GO:0005739=GO_REF:0000019, GO:0034641=Reactome:REACT_13, GO:0030644=GO_REF:0000019, GO:0006600=Reactome:REACT_813, GO:0007420=GO_REF:0000019, GO:0016301=GO_REF:0000038, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_11156} P12277 Creatine kinase B-type protein 20130415 {GO:0005515=IPI, GO:0004111=IEA, GO:0005739=IEA, GO:0034641=TAS, GO:0030644=IEA, GO:0006600=TAS, GO:0007420=IEA, GO:0016301=IEA, GO:0044281=TAS, GO:0005524=IEA, GO:0005829=TAS} brain development, cellular chloride ion homeostasis, cellular nitrogen compound metabolic process, creatine metabolic process, small molecule metabolic process cytosol, mitochondrion ATP binding, creatine kinase activity, kinase activity, protein binding Human UniProtKB:Q96DX5 CKLF UniProtKB UniProtKB {GO:0008009=PMID:11415443, GO:0008283=PMID:11415443, GO:0030593=PMID:11415443, GO:0005576=PMID:11415443, GO:0048247=PMID:11415443, GO:0016021=PMID:11415443, GO:0048246=PMID:11415443, GO:0032940=PMID:11415443, GO:0005615=GO_REF:0000037} Q9UBR5 Chemokine-like factor protein 20040408 {GO:0008009=IDA, GO:0008283=IDA, GO:0030593=IDA, GO:0005576=IDA, GO:0048247=IDA, GO:0016021=IDA, GO:0048246=IDA, GO:0032940=IDA, GO:0005615=IEA} cell proliferation, lymphocyte chemotaxis, macrophage chemotaxis, neutrophil chemotaxis, secretion by cell extracellular region, extracellular space, integral to membrane chemokine activity Human CKM Reactome UniProtKB {GO:0004111=GO_REF:0000003, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000029, GO:0006600=Reactome:REACT_813, GO:0046314=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_11156} P06732 Creatine kinase M-type protein 20070718 {GO:0004111=IEA, GO:0034641=TAS, GO:0005737=NAS, GO:0006600=TAS, GO:0046314=IEA, GO:0044281=TAS, GO:0005524=IEA, GO:0005829=TAS} cellular nitrogen compound metabolic process, creatine metabolic process, phosphocreatine biosynthetic process, small molecule metabolic process cytoplasm, cytosol ATP binding, creatine kinase activity Human CKMT1A Reactome UniProtKB {GO:0005739=PMID:2914937, GO:0004111=GO_REF:0000003, GO:0034641=Reactome:REACT_13, GO:0006600=Reactome:REACT_813, GO:0016301=GO_REF:0000038, GO:0005743=Reactome:REACT_11155, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037} P12532 Creatine kinase U-type, mitochondrial protein 20070718 {GO:0005739=TAS, GO:0004111=IEA, GO:0034641=TAS, GO:0006600=TAS, GO:0016301=IEA, GO:0005743=TAS, GO:0044281=TAS, GO:0005524=IEA} cellular nitrogen compound metabolic process, creatine metabolic process, small molecule metabolic process mitochondrial inner membrane, mitochondrion ATP binding, creatine kinase activity, kinase activity Human CKMT1B InterPro UniProtKB {GO:0016301=GO_REF:0000002, GO:0005524=GO_REF:0000038} J3KQ93 Creatine kinase U-type, mitochondrial protein 20130413 {GO:0016301=IEA, GO:0005524=IEA} ATP binding, kinase activity Human InterPro:IPR022414 CKMT2 Reactome UniProtKB {GO:0004111=GO_REF:0000003, GO:0005739=PMID:2324105, GO:0034641=Reactome:REACT_13, GO:0006936=PMID:2324105, GO:0006600=Reactome:REACT_813, GO:0016301=GO_REF:0000002, GO:0005743=Reactome:REACT_11155, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037} P17540 Creatine kinase S-type, mitochondrial protein 20070718 {GO:0004111=IEA, GO:0005739=TAS, GO:0034641=TAS, GO:0006936=TAS, GO:0006600=TAS, GO:0016301=IEA, GO:0005743=TAS, GO:0044281=TAS, GO:0005524=IEA} cellular nitrogen compound metabolic process, creatine metabolic process, muscle contraction, small molecule metabolic process mitochondrial inner membrane, mitochondrion ATP binding, creatine kinase activity, kinase activity Human CKS1B UniProtKB UniProtKB {GO:0005515=PMID:12813041, GO:0000084=Reactome:REACT_899, GO:0007049=GO_REF:0000002, GO:0000082=Reactome:REACT_1783, GO:0016301=GO_REF:0000038, GO:0008283=PMID:2227411, GO:0005654=Reactome:REACT_111194, GO:0016538=GO_REF:0000002, GO:0000079=PMID:8601310, GO:0000278=Reactome:REACT_152, GO:0000080=Reactome:REACT_1590, GO:0051301=GO_REF:0000037} Q9BZU3 PNAS-18 protein 20130413 {GO:0005515=IPI, GO:0000084=TAS, GO:0007049=IEA, GO:0000082=TAS, GO:0016301=IEA, GO:0008283=TAS, GO:0005654=TAS, GO:0016538=IEA, GO:0000079=TAS, GO:0000278=TAS, GO:0000080=TAS, GO:0051301=IEA} G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, cell cycle, cell division, cell proliferation, mitotic cell cycle, regulation of cyclin-dependent protein serine/threonine kinase activity nucleoplasm cyclin-dependent protein serine/threonine kinase regulator activity, kinase activity, protein binding Human UniProtKB-KW:KW-0418 CKS2 PINC UniProtKB {GO:0007049=PMID:15504738, GO:0007127=GO_REF:0000019, GO:0008283=PMID:8211159, GO:0048015=PMID:15504738, GO:0016538=GO_REF:0000002, GO:0000079=PMID:2227411, GO:0007051=PMID:15504738, GO:0051301=GO_REF:0000037} P33552 Cyclin-dependent kinases regulatory subunit 2 protein 20030904 {GO:0007049=NAS, GO:0007127=IEA, GO:0008283=TAS, GO:0048015=NAS, GO:0016538=IEA, GO:0000079=TAS, GO:0007051=NAS, GO:0051301=IEA} cell cycle, cell division, cell proliferation, meiosis I, phosphatidylinositol-mediated signaling, regulation of cyclin-dependent protein serine/threonine kinase activity, spindle organization cyclin-dependent protein serine/threonine kinase regulator activity Human CLASP1 IntAct UniProtKB {GO:0005515=PMID:11290329, GO:0005828=PMID:12837247, GO:0008017=PMID:12837247, GO:0000236=Reactome:REACT_682, GO:0005881=PMID:11290329, GO:0030981=PMID:12837247, GO:0034453=PMID:17543864, GO:0001578=PMID:12837247, GO:0051294=PMID:21822276, GO:0005829=Reactome:REACT_150414, GO:0051010=PMID:12837247, GO:0007411=Reactome:REACT_18266, GO:0000086=Reactome:REACT_2203, GO:0031023=PMID:17543864, GO:0000087=Reactome:REACT_910, GO:0005876=PMID:12837247, GO:0005938=PMID:17113391, GO:0010458=PMID:16866869, GO:0005813=PMID:21399614, GO:0005794=PMID:15631994, GO:0031111=PMID:12837247, GO:0000226=PMID:15631994, GO:0007163=PMID:15928712, GO:0007020=PMID:17543864, GO:0000777=GO_REF:0000039, GO:0007026=PMID:16866869, GO:0000776=PMID:12837247, GO:0043515=PMID:12837247, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0031592=PMID:16914514, GO:0051301=PMID:21822276} Q7Z460 CLIP-associating protein 1 protein 20130415 {GO:0005515=IPI, GO:0005828=TAS, GO:0008017=IMP, GO:0000236=TAS, GO:0005881=IDA, GO:0030981=IDA, GO:0034453=IMP, GO:0001578=IMP, GO:0051294=IMP, GO:0005829=TAS, GO:0051010=IDA, GO:0007411=TAS, GO:0000086=TAS, GO:0031023=IMP, GO:0000087=TAS, GO:0005876=IDA, GO:0005938=IDA, GO:0010458=IMP, GO:0005813=IDA, GO:0005794=IDA, GO:0031111=IMP, GO:0000226=IGI, GO:0007163=NAS, GO:0007020=IMP, GO:0000777=IEA, GO:0007026=IMP, GO:0000776=IDA, GO:0043515=IMP, GO:0000278=TAS, GO:0000090=TAS, GO:0031592=IDA, GO:0051301=IDA} G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, axon guidance, cell division, establishment of spindle orientation, establishment or maintenance of cell polarity, exit from mitosis, microtubule anchoring, microtubule bundle formation, microtubule cytoskeleton organization, microtubule nucleation, microtubule organizing center organization, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, negative regulation of microtubule depolymerization, negative regulation of microtubule polymerization or depolymerization Golgi apparatus, cell cortex, centrosomal corona, centrosome, condensed chromosome kinetochore, cortical microtubule cytoskeleton, cytoplasmic microtubule, cytosol, kinetochore, kinetochore microtubule, spindle microtubule kinetochore binding, microtubule binding, microtubule plus-end binding, protein binding Human UniProtKB:O55156 CLASP2 IntAct UniProtKB {GO:0005828=PMID:12837247, GO:0008017=GO_REF:0000019, GO:0005515=PMID:11290329, GO:0005802=PMID:17543864, GO:0000236=Reactome:REACT_682, GO:0005881=PMID:11290329, GO:0034453=PMID:17543864, GO:0005886=PMID:20937854, GO:0005829=Reactome:REACT_150414, GO:0005737=PMID:11290329, GO:0051010=PMID:19632184, GO:0007411=Reactome:REACT_18266, GO:0008107=PMID:11290329, GO:0031023=PMID:17543864, GO:0000087=Reactome:REACT_910, GO:0005938=PMID:17113391, GO:0005794=PMID:11290329, GO:0005815=GO_REF:0000039, GO:0031110=PMID:11290329, GO:0005874=PMID:20937854, GO:0032886=PMID:20937854, GO:0032587=PMID:20937854, GO:0007163=PMID:15928712, GO:0016477=GO_REF:0000019, GO:0007020=PMID:17543864, GO:0000777=GO_REF:0000039, GO:0007026=PMID:11290329, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} O75122 CLIP-associating protein 2 protein 20130415 {GO:0005828=TAS, GO:0008017=IEA, GO:0005515=IPI, GO:0005802=IDA, GO:0000236=TAS, GO:0005881=IDA, GO:0034453=IMP, GO:0005886=IDA, GO:0005829=TAS, GO:0005737=NAS, GO:0051010=IDA, GO:0007411=TAS, GO:0008107=NAS, GO:0031023=IMP, GO:0000087=TAS, GO:0005938=IDA, GO:0005794=IDA, GO:0005815=IEA, GO:0031110=IMP, GO:0005874=IDA, GO:0032886=IMP, GO:0032587=IDA, GO:0007163=TAS, GO:0016477=IEA, GO:0007020=IMP, GO:0000777=IEA, GO:0007026=NAS, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, axon guidance, cell division, cell migration, establishment or maintenance of cell polarity, microtubule anchoring, microtubule nucleation, microtubule organizing center organization, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, negative regulation of microtubule depolymerization, regulation of microtubule polymerization or depolymerization, regulation of microtubule-based process Golgi apparatus, cell cortex, condensed chromosome kinetochore, cytoplasm, cytoplasmic microtubule, cytosol, kinetochore microtubule, microtubule, microtubule organizing center, plasma membrane, ruffle membrane, trans-Golgi network galactoside 2-alpha-L-fucosyltransferase activity, microtubule binding, microtubule plus-end binding, protein binding Human UniProtKB:O55156 CLASRP UniProtKB UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0005634=GO_REF:0000039} Q8N2M8 CLK4-associating serine/arginine rich protein protein 20130413 {GO:0008380=IEA, GO:0006397=IEA, GO:0005634=IEA} RNA splicing, mRNA processing nucleus Human UniProtKB-SubCell:SL-0191 CLCA1 GOC UniProtKB {GO:0006821=PMID:9828122, GO:0005887=PMID:9828122, GO:0006810=PMID:9828122, GO:0006816=GO_REF:0000037, GO:0030141=GO_REF:0000019, GO:0005254=PMID:9828122, GO:0005615=GO_REF:0000039} A8K7I4 Calcium-activated chloride channel regulator 1 protein 20130413 {GO:0006821=TAS, GO:0005887=TAS, GO:0006810=TAS, GO:0006816=IEA, GO:0030141=IEA, GO:0005254=TAS, GO:0005615=IEA} calcium ion transport, chloride transport, transport extracellular space, integral to plasma membrane, secretory granule chloride channel activity Human CLCA2 PINC UniProtKB {GO:0030054=GO_REF:0000039, GO:0009925=GO_REF:0000039, GO:0005887=PMID:10362588, GO:0006810=PMID:10362588, GO:0005576=GO_REF:0000039, GO:0007155=GO_REF:0000037, GO:0005254=GO_REF:0000019, GO:0015276=GO_REF:0000019} Q9UQC9 Calcium-activated chloride channel regulator 2 protein 20090630 {GO:0030054=IEA, GO:0009925=IEA, GO:0005887=TAS, GO:0006810=TAS, GO:0005576=IEA, GO:0007155=IEA, GO:0005254=IEA, GO:0015276=IEA} cell adhesion, transport basal plasma membrane, cell junction, extracellular region, integral to plasma membrane chloride channel activity, ligand-gated ion channel activity Human CLCC1 HPA UniProtKB {GO:0005794=GO_REF:0000039, GO:0005783=GO_REF:0000052, GO:0005634=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q96S66 Chloride channel CLIC-like protein 1 protein 20101115 {GO:0005794=IEA, GO:0005783=IDA, GO:0005634=IEA, GO:0016021=IEA, GO:0043231=IDA} Golgi apparatus, endoplasmic reticulum, integral to membrane, intracellular membrane-bounded organelle, nucleus Human CLCF1 BHF-UCL UniProtKB {GO:0005515=PMID:10966616, GO:0043066=PMID:14632778, GO:0008284=PMID:11285233, GO:0048295=GO_REF:0000024, GO:0046982=PMID:10966616, GO:0030890=GO_REF:0000024, GO:0042517=PMID:11285233, GO:0019221=PMID:10500198, GO:0097059=PMID:11285233, GO:0005102=PMID:15272019, GO:0005576=PMID:10966616, GO:0005125=PMID:10966616, GO:0007259=GO_REF:0000024, GO:0097058=PMID:10966616, GO:0005127=PMID:11285233, GO:0043524=PMID:11285233, GO:0048711=GO_REF:0000024, GO:0002639=GO_REF:0000024, GO:0030183=GO_REF:0000024, GO:0008083=PMID:14632778, GO:0007166=GO_REF:0000024} Q9UBD9 Cardiotrophin-like cytokine factor 1 protein 20120404 {GO:0005515=IPI, GO:0043066=TAS, GO:0008284=IDA, GO:0048295=ISS, GO:0046982=IDA, GO:0030890=ISS, GO:0042517=IDA, GO:0019221=NAS, GO:0097059=IDA, GO:0005102=IPI, GO:0005576=IDA, GO:0005125=IDA, GO:0007259=ISS, GO:0097058=IDA, GO:0005127=IDA, GO:0043524=IDA, GO:0048711=ISS, GO:0002639=ISS, GO:0030183=ISS, GO:0008083=TAS, GO:0007166=ISS} B cell differentiation, JAK-STAT cascade, cell surface receptor signaling pathway, cytokine-mediated signaling pathway, negative regulation of apoptotic process, negative regulation of neuron apoptotic process, positive regulation of B cell proliferation, positive regulation of astrocyte differentiation, positive regulation of cell proliferation, positive regulation of immunoglobulin production, positive regulation of isotype switching to IgE isotypes, positive regulation of tyrosine phosphorylation of Stat3 protein CNTFR-CLCF1 complex, CRLF-CLCF1 complex, extracellular region ciliary neurotrophic factor receptor binding, cytokine activity, growth factor activity, protein binding, protein heterodimerization activity, receptor binding Human CLCN1 Reactome UniProtKB {GO:0042383=GO_REF:0000019, GO:0034220=Reactome:REACT_25300, GO:0006936=PMID:1379744, GO:0005886=Reactome:REACT_160109, GO:0016020=GO_REF:0000002, GO:0005887=PMID:9122265, GO:0005247=GO_REF:0000002, GO:0006810=PMID:9122265, GO:0034707=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0005254=PMID:1379744, GO:0019227=GO_REF:0000019} P35523 Chloride channel protein 1 protein 20130301 {GO:0042383=IEA, GO:0034220=TAS, GO:0006936=TAS, GO:0005886=TAS, GO:0016020=IEA, GO:0005887=TAS, GO:0005247=IEA, GO:0006810=TAS, GO:0034707=IEA, GO:0055085=TAS, GO:0005254=TAS, GO:0019227=IEA} ion transmembrane transport, muscle contraction, neuronal action potential propagation, transmembrane transport, transport chloride channel complex, integral to plasma membrane, membrane, plasma membrane, sarcolemma chloride channel activity, voltage-gated chloride channel activity Human CLCN2 Reactome UniProtKB {GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_160109, GO:0060041=GO_REF:0000019, GO:0005247=GO_REF:0000019, GO:0006810=PMID:7795595, GO:0034707=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0060689=GO_REF:0000019} P51788 Chloride channel protein 2 protein 20130301 {GO:0034220=TAS, GO:0005886=TAS, GO:0060041=IEA, GO:0005247=IEA, GO:0006810=TAS, GO:0034707=IEA, GO:0055085=TAS, GO:0060689=IEA} cell differentiation involved in salivary gland development, ion transmembrane transport, retina development in camera-type eye, transmembrane transport, transport chloride channel complex, plasma membrane voltage-gated chloride channel activity Human CLCN3 Reactome UniProtKB {GO:0005515=PMID:12471024, GO:0005254=PMID:12471024, GO:0006885=PMID:12471024, GO:0042803=PMID:12471024, GO:0005622=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0015297=GO_REF:0000037, GO:0034220=Reactome:REACT_25300, GO:0006810=PMID:7665160, GO:0030658=GO_REF:0000039, GO:0012506=PMID:12471024, GO:0005794=PMID:12471024, GO:0046982=PMID:12471024, GO:0009986=PMID:12471024, GO:0005770=PMID:12471024, GO:0005247=GO_REF:0000019, GO:0030165=PMID:12471024, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0000139=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0048388=PMID:12471024, GO:0031901=GO_REF:0000039, GO:0031902=Reactome:REACT_160116, GO:0016021=PMID:12471024, GO:0005769=PMID:12471024} P51790 H(+)/Cl(-) exchange transporter 3 protein 20130301 {GO:0005515=IPI, GO:0005254=TAS, GO:0006885=TAS, GO:0042803=NAS, GO:0005622=IEA, GO:0016324=IEA, GO:0015297=IEA, GO:0034220=TAS, GO:0006810=TAS, GO:0030658=IEA, GO:0012506=IDA, GO:0005794=IDA, GO:0046982=IDA, GO:0009986=NAS, GO:0005770=IDA, GO:0005247=IEA, GO:0030165=IDA, GO:0055085=TAS, GO:0005524=IEA, GO:0000139=IEA, GO:0016020=IEA, GO:0048388=TAS, GO:0031901=IEA, GO:0031902=TAS, GO:0016021=TAS, GO:0005769=IDA} endosomal lumen acidification, ion transmembrane transport, regulation of pH, transmembrane transport, transport Golgi apparatus, Golgi membrane, apical plasma membrane, cell surface, early endosome, early endosome membrane, integral to membrane, intracellular, late endosome, late endosome membrane, membrane, transport vesicle membrane, vesicle membrane ATP binding, PDZ domain binding, antiporter activity, chloride channel activity, protein binding, protein heterodimerization activity, protein homodimerization activity, voltage-gated chloride channel activity Human CLCN4 Reactome UniProtKB {GO:0006821=PMID:10564087, GO:0005247=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0005254=PMID:10564087, GO:0055085=Reactome:REACT_15518, GO:0015297=GO_REF:0000037, GO:0034220=Reactome:REACT_25300, GO:0031901=GO_REF:0000039, GO:0031902=GO_REF:0000039, GO:0006810=PMID:8069296, GO:0016021=GO_REF:0000037, GO:0005216=GO_REF:0000002, GO:0010008=Reactome:REACT_160268} P51793 H(+)/Cl(-) exchange transporter 4 protein 20130301 {GO:0006821=IDA, GO:0005247=IEA, GO:0005524=IEA, GO:0005254=IDA, GO:0055085=TAS, GO:0015297=IEA, GO:0034220=TAS, GO:0031901=IEA, GO:0031902=IEA, GO:0006810=TAS, GO:0016021=IEA, GO:0005216=IEA, GO:0010008=TAS} chloride transport, ion transmembrane transport, transmembrane transport, transport early endosome membrane, endosome membrane, integral to membrane, late endosome membrane ATP binding, antiporter activity, chloride channel activity, ion channel activity, voltage-gated chloride channel activity Human CLCN5 Reactome UniProtKB {GO:0007588=PMID:8559248, GO:0005247=GO_REF:0000002, GO:0045177=PMID:14675051, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0005254=PMID:8559248, GO:0006897=GO_REF:0000019, GO:0015297=GO_REF:0000037, GO:0034220=Reactome:REACT_25300, GO:0000139=GO_REF:0000039, GO:0016020=PMID:14675051, GO:0005887=PMID:8559248, GO:0006810=PMID:8559248, GO:0010008=Reactome:REACT_160268} P51795 H(+)/Cl(-) exchange transporter 5 protein 20130301 {GO:0007588=TAS, GO:0005247=IEA, GO:0045177=IDA, GO:0055085=TAS, GO:0005524=IEA, GO:0005254=TAS, GO:0006897=IEA, GO:0015297=IEA, GO:0034220=TAS, GO:0000139=IEA, GO:0016020=IDA, GO:0005887=TAS, GO:0006810=TAS, GO:0010008=TAS} endocytosis, excretion, ion transmembrane transport, transmembrane transport, transport Golgi membrane, apical part of cell, endosome membrane, integral to plasma membrane, membrane ATP binding, antiporter activity, chloride channel activity, voltage-gated chloride channel activity Human CLCN6 InterPro UniProtKB {GO:0007165=PMID:9224655, GO:0006821=PMID:8543009, GO:0034220=Reactome:REACT_25300, GO:0015297=GO_REF:0000037, GO:0016020=GO_REF:0000002, GO:0005247=GO_REF:0000002, GO:0016021=PMID:8543009, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0010008=Reactome:REACT_160268, GO:0006884=PMID:8543009} Q5SNW4 Chloride transport protein 6 protein 20130413 {GO:0007165=NAS, GO:0006821=NAS, GO:0034220=TAS, GO:0015297=IEA, GO:0016020=IEA, GO:0005247=IEA, GO:0016021=NAS, GO:0055085=TAS, GO:0005524=IEA, GO:0010008=TAS, GO:0006884=NAS} cell volume homeostasis, chloride transport, ion transmembrane transport, signal transduction, transmembrane transport endosome membrane, integral to membrane, membrane ATP binding, antiporter activity, voltage-gated chloride channel activity Human InterPro:IPR002248 CLCN7 Reactome UniProtKB {GO:0034220=Reactome:REACT_25300, GO:0015297=GO_REF:0000037, GO:0016020=GO_REF:0000002, GO:0005247=GO_REF:0000002, GO:0006810=PMID:8543009, GO:0016021=GO_REF:0000037, GO:0031410=GO_REF:0000019, GO:0005765=Reactome:REACT_160230, GO:0055085=Reactome:REACT_15518, GO:0005254=PMID:8543009, GO:0005524=GO_REF:0000037, GO:0009268=GO_REF:0000019} P51798 H(+)/Cl(-) exchange transporter 7 protein 20121126 {GO:0034220=TAS, GO:0015297=IEA, GO:0016020=IEA, GO:0005247=IEA, GO:0006810=TAS, GO:0016021=IEA, GO:0031410=IEA, GO:0005765=TAS, GO:0055085=TAS, GO:0005254=TAS, GO:0005524=IEA, GO:0009268=IEA} ion transmembrane transport, response to pH, transmembrane transport, transport cytoplasmic vesicle, integral to membrane, lysosomal membrane, membrane ATP binding, antiporter activity, chloride channel activity, voltage-gated chloride channel activity Human CLCNKA Reactome UniProtKB {GO:0007588=PMID:8041726, GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_160109, GO:0005887=PMID:8041726, GO:0005247=GO_REF:0000002, GO:0006810=PMID:8041726, GO:0034707=GO_REF:0000037, GO:0055085=Reactome:REACT_15518} P51800 Chloride channel protein ClC-Ka protein 20121126 {GO:0007588=TAS, GO:0034220=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0005247=IEA, GO:0006810=TAS, GO:0034707=IEA, GO:0055085=TAS} excretion, ion transmembrane transport, transmembrane transport, transport chloride channel complex, integral to plasma membrane, plasma membrane voltage-gated chloride channel activity Human CLCNKB Reactome UniProtKB {GO:0007588=PMID:9326936, GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_160109, GO:0005887=PMID:8041726, GO:0005247=GO_REF:0000002, GO:0006810=PMID:8041726, GO:0034707=GO_REF:0000037, GO:0055085=Reactome:REACT_15518} P51801 Chloride channel protein ClC-Kb protein 20121126 {GO:0007588=TAS, GO:0034220=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0005247=IEA, GO:0006810=TAS, GO:0034707=IEA, GO:0055085=TAS} excretion, ion transmembrane transport, transmembrane transport, transport chloride channel complex, integral to plasma membrane, plasma membrane voltage-gated chloride channel activity Human CLDN1 MGI UniProtKB {GO:0016324=GO_REF:0000019, GO:0016338=GO_REF:0000024, GO:0005887=PMID:9647647, GO:0005198=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0016021=PMID:9931503, GO:0005923=GO_REF:0000024, GO:0007155=PMID:9647647, GO:0016328=GO_REF:0000019, GO:0045216=PMID:20164257, GO:0042802=GO_REF:0000024} O95832 Claudin-1 protein 20120514 {GO:0016324=IEA, GO:0016338=ISS, GO:0005887=TAS, GO:0005198=IEA, GO:0019048=IEA, GO:0016021=TAS, GO:0005923=ISS, GO:0007155=TAS, GO:0016328=IEA, GO:0045216=IMP, GO:0042802=ISS} calcium-independent cell-cell adhesion, cell adhesion, cell-cell junction organization, virus-host interaction apical plasma membrane, integral to membrane, integral to plasma membrane, lateral plasma membrane, tight junction identical protein binding, structural molecule activity Human CLDN10 ENSEMBL UniProtKB {GO:0016338=GO_REF:0000024, GO:0016020=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0005198=GO_REF:0000002, GO:0005923=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007155=PMID:10508613, GO:0042802=GO_REF:0000024} Q5W075 Claudin-10 protein 20130413 {GO:0016338=ISS, GO:0016020=IEA, GO:0005886=IEA, GO:0005198=IEA, GO:0005923=IEA, GO:0016021=IEA, GO:0007155=TAS, GO:0042802=ISS} calcium-independent cell-cell adhesion, cell adhesion integral to membrane, membrane, plasma membrane, tight junction identical protein binding, structural molecule activity Human Ensembl:ENSMUSP00000097889 CLDN11 UniProtKB UniProtKB {GO:0016338=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0005198=GO_REF:0000002, GO:0007283=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0005923=GO_REF:0000024, GO:0008366=GO_REF:0000019, GO:0042802=GO_REF:0000024} O75508 Claudin-11 protein 20050322 {GO:0016338=ISS, GO:0005886=IEA, GO:0005198=IEA, GO:0007283=IEA, GO:0016021=IEA, GO:0005923=ISS, GO:0008366=IEA, GO:0042802=ISS} axon ensheathment, calcium-independent cell-cell adhesion, spermatogenesis integral to membrane, plasma membrane, tight junction identical protein binding, structural molecule activity Human UniProtKB:O88551 CLDN12 Reactome UniProtKB {GO:0016338=GO_REF:0000024, GO:0070830=Reactome:REACT_19373, GO:0005886=GO_REF:0000039, GO:0005198=GO_REF:0000002, GO:0034329=Reactome:REACT_20676, GO:0016021=GO_REF:0000037, GO:0005923=GO_REF:0000024, GO:0045216=Reactome:REACT_19331, GO:0042802=GO_REF:0000024, GO:0071944=GO_REF:0000019} P56749 Claudin-12 protein 20130228 {GO:0016338=ISS, GO:0070830=TAS, GO:0005886=IEA, GO:0005198=IEA, GO:0034329=TAS, GO:0016021=IEA, GO:0005923=ISS, GO:0045216=TAS, GO:0042802=ISS, GO:0071944=IEA} calcium-independent cell-cell adhesion, cell junction assembly, cell-cell junction organization, tight junction assembly cell periphery, integral to membrane, plasma membrane, tight junction identical protein binding, structural molecule activity Human CLDN15 Reactome UniProtKB {GO:0016338=GO_REF:0000024, GO:0070830=Reactome:REACT_19373, GO:0005886=GO_REF:0000039, GO:0005198=GO_REF:0000002, GO:0034329=Reactome:REACT_20676, GO:0016021=GO_REF:0000037, GO:0005923=GO_REF:0000024, GO:0045216=Reactome:REACT_19331, GO:0042802=GO_REF:0000024} P56746 Claudin-15 protein 20130228 {GO:0016338=ISS, GO:0070830=TAS, GO:0005886=IEA, GO:0005198=IEA, GO:0034329=TAS, GO:0016021=IEA, GO:0005923=ISS, GO:0045216=TAS, GO:0042802=ISS} calcium-independent cell-cell adhesion, cell junction assembly, cell-cell junction organization, tight junction assembly integral to membrane, plasma membrane, tight junction identical protein binding, structural molecule activity Human CLDN16 GOC UniProtKB {GO:0007588=PMID:10390358, GO:0015693=PMID:10390358, GO:0016338=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0005198=GO_REF:0000002, GO:0015095=PMID:10390358, GO:0006875=PMID:10390358, GO:0016021=GO_REF:0000037, GO:0005923=GO_REF:0000024, GO:0042802=GO_REF:0000024} Q9Y5I7 Claudin-16 protein 20130413 {GO:0007588=TAS, GO:0015693=TAS, GO:0016338=ISS, GO:0005886=IEA, GO:0016020=IEA, GO:0005198=IEA, GO:0015095=TAS, GO:0006875=TAS, GO:0016021=IEA, GO:0005923=ISS, GO:0042802=ISS} calcium-independent cell-cell adhesion, cellular metal ion homeostasis, excretion, magnesium ion transport integral to membrane, membrane, plasma membrane, tight junction identical protein binding, magnesium ion transmembrane transporter activity, structural molecule activity Human CLDN17 Reactome UniProtKB {GO:0016338=GO_REF:0000024, GO:0005794=PMID:16780588, GO:0070830=Reactome:REACT_19373, GO:0005886=PMID:16780588, GO:0005198=GO_REF:0000002, GO:0034329=Reactome:REACT_20676, GO:0005923=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0045216=Reactome:REACT_19331, GO:0042802=GO_REF:0000024} P56750 Claudin-17 protein 20130228 {GO:0016338=ISS, GO:0005794=IDA, GO:0070830=TAS, GO:0005886=IDA, GO:0005198=IEA, GO:0034329=TAS, GO:0005923=ISS, GO:0016021=IEA, GO:0045216=TAS, GO:0042802=ISS} calcium-independent cell-cell adhesion, cell junction assembly, cell-cell junction organization, tight junction assembly Golgi apparatus, integral to membrane, plasma membrane, tight junction identical protein binding, structural molecule activity Human CLDN18 Reactome UniProtKB {GO:0016338=GO_REF:0000024, GO:0070830=Reactome:REACT_19373, GO:0005886=GO_REF:0000039, GO:0005198=GO_REF:0000002, GO:0034329=Reactome:REACT_20676, GO:0016021=GO_REF:0000037, GO:0005923=GO_REF:0000024, GO:0045216=Reactome:REACT_19331, GO:0042802=GO_REF:0000024} P56856 Claudin-18 protein 20130228 {GO:0016338=ISS, GO:0070830=TAS, GO:0005886=IEA, GO:0005198=IEA, GO:0034329=TAS, GO:0016021=IEA, GO:0005923=ISS, GO:0045216=TAS, GO:0042802=ISS} calcium-independent cell-cell adhesion, cell junction assembly, cell-cell junction organization, tight junction assembly integral to membrane, plasma membrane, tight junction identical protein binding, structural molecule activity Human CLDN19 MGI UniProtKB {GO:0005634=GO_REF:0000019, GO:0019227=GO_REF:0000019, GO:0042802=GO_REF:0000024, GO:0043297=GO_REF:0000019, GO:0016323=PMID:16427635, GO:0043296=PMID:16427635, GO:0005737=GO_REF:0000019, GO:0016338=GO_REF:0000024, GO:0005198=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0005923=PMID:16427635, GO:0007601=GO_REF:0000037, GO:0050896=GO_REF:0000037} Q8N6F1 Claudin-19 protein 20070604 {GO:0005634=IEA, GO:0019227=IEA, GO:0042802=ISS, GO:0043297=IEA, GO:0016323=IDA, GO:0043296=IDA, GO:0005737=IEA, GO:0016338=ISS, GO:0005198=IEA, GO:0016021=IEA, GO:0005923=IDA, GO:0007601=IEA, GO:0050896=IEA} apical junction assembly, calcium-independent cell-cell adhesion, neuronal action potential propagation, response to stimulus, visual perception apical junction complex, basolateral plasma membrane, cytoplasm, integral to membrane, nucleus, tight junction identical protein binding, structural molecule activity Human CLDN2 UniProtKB UniProtKB {GO:0016338=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0005198=GO_REF:0000002, GO:0005923=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0042802=GO_REF:0000024} P57739 Claudin-2 protein 20050322 {GO:0016338=ISS, GO:0005886=IEA, GO:0005198=IEA, GO:0005923=ISS, GO:0016021=IEA, GO:0042802=ISS} calcium-independent cell-cell adhesion integral to membrane, plasma membrane, tight junction identical protein binding, structural molecule activity Human UniProtKB:O88552 CLDN20 Reactome UniProtKB {GO:0016338=GO_REF:0000024, GO:0070830=Reactome:REACT_19373, GO:0005886=GO_REF:0000039, GO:0005198=GO_REF:0000002, GO:0034329=Reactome:REACT_20676, GO:0005923=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0045216=Reactome:REACT_19331, GO:0042802=GO_REF:0000024} P56880 Claudin-20 protein 20130228 {GO:0016338=ISS, GO:0070830=TAS, GO:0005886=IEA, GO:0005198=IEA, GO:0034329=TAS, GO:0005923=ISS, GO:0016021=IEA, GO:0045216=TAS, GO:0042802=ISS} calcium-independent cell-cell adhesion, cell junction assembly, cell-cell junction organization, tight junction assembly integral to membrane, plasma membrane, tight junction identical protein binding, structural molecule activity Human CLDN3 PINC UniProtKB {GO:0001666=PMID:15174142, GO:0016338=GO_REF:0000019, GO:0005887=PMID:9334247, GO:0005198=GO_REF:0000002, GO:0016021=PMID:9441748, GO:0005923=GO_REF:0000039, GO:0004888=PMID:9334247, GO:0042802=GO_REF:0000019} O15551 Claudin-3 protein 20030904 {GO:0001666=IEP, GO:0016338=IEA, GO:0005887=TAS, GO:0005198=IEA, GO:0016021=TAS, GO:0005923=IEA, GO:0004888=TAS, GO:0042802=IEA} calcium-independent cell-cell adhesion, response to hypoxia integral to membrane, integral to plasma membrane, tight junction identical protein binding, structural molecule activity, transmembrane signaling receptor activity Human CLDN4 UniProtKB UniProtKB {GO:0007565=GO_REF:0000019, GO:0005886=PMID:9892664, GO:0016328=GO_REF:0000019, GO:0016327=GO_REF:0000019, GO:0042802=GO_REF:0000024, GO:0016324=GO_REF:0000019, GO:0009925=GO_REF:0000019, GO:0016338=GO_REF:0000024, GO:0005198=GO_REF:0000002, GO:0005887=PMID:9334247, GO:0032570=GO_REF:0000019, GO:0005923=GO_REF:0000024, GO:0004888=PMID:9334247} O14493 Claudin-4 protein 20050322 {GO:0007565=IEA, GO:0005886=TAS, GO:0016328=IEA, GO:0016327=IEA, GO:0042802=ISS, GO:0016324=IEA, GO:0009925=IEA, GO:0016338=ISS, GO:0005198=IEA, GO:0005887=TAS, GO:0032570=IEA, GO:0005923=ISS, GO:0004888=TAS} calcium-independent cell-cell adhesion, female pregnancy, response to progesterone stimulus apical plasma membrane, apicolateral plasma membrane, basal plasma membrane, integral to plasma membrane, lateral plasma membrane, plasma membrane, tight junction identical protein binding, structural molecule activity, transmembrane signaling receptor activity Human UniProtKB:Q9Z0G9 CLDN5 UniProtKB UniProtKB {GO:0043220=GO_REF:0000019, GO:0016338=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0005911=PMID:18065521, GO:0005198=GO_REF:0000002, GO:0042552=GO_REF:0000019, GO:0033270=GO_REF:0000019, GO:0005923=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0042802=GO_REF:0000024} O00501 Claudin-5 protein 20091030 {GO:0043220=IEA, GO:0016338=ISS, GO:0005886=IEA, GO:0005911=IDA, GO:0005198=IEA, GO:0042552=IEA, GO:0033270=IEA, GO:0005923=ISS, GO:0016021=IEA, GO:0042802=ISS} calcium-independent cell-cell adhesion, myelination Schmidt-Lanterman incisure, cell-cell junction, integral to membrane, paranode region of axon, plasma membrane, tight junction identical protein binding, structural molecule activity Human CLDN6 UniProtKB UniProtKB {GO:0016338=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0005198=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005923=GO_REF:0000024, GO:0042802=GO_REF:0000024} P56747 Claudin-6 protein 20050322 {GO:0016338=ISS, GO:0005886=IEA, GO:0016020=IEA, GO:0005198=IEA, GO:0016021=IEA, GO:0005923=ISS, GO:0042802=ISS} calcium-independent cell-cell adhesion integral to membrane, membrane, plasma membrane, tight junction identical protein binding, structural molecule activity Human UniProtKB:Q9Z0G9 CLDN7 UniProtKB UniProtKB {GO:0005515=PMID:16054130, GO:0016338=GO_REF:0000024, GO:0005886=GO_REF:0000038, GO:0005198=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005923=GO_REF:0000024, GO:0016328=GO_REF:0000039, GO:0042802=GO_REF:0000024} O95471 Claudin-7 protein 20101004 {GO:0005515=IPI, GO:0016338=ISS, GO:0005886=IEA, GO:0005198=IEA, GO:0016021=IEA, GO:0005923=ISS, GO:0016328=IEA, GO:0042802=ISS} calcium-independent cell-cell adhesion integral to membrane, lateral plasma membrane, plasma membrane, tight junction identical protein binding, protein binding, structural molecule activity Human UniProtKB:P16422 CLDN8 UniProtKB UniProtKB {GO:0016338=GO_REF:0000024, GO:0005886=PMID:16780588, GO:0005783=PMID:16780588, GO:0005198=GO_REF:0000002, GO:0005923=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0042802=GO_REF:0000024} P56748 Claudin-8 protein 20050322 {GO:0016338=ISS, GO:0005886=IDA, GO:0005783=IDA, GO:0005198=IEA, GO:0005923=ISS, GO:0016021=IEA, GO:0042802=ISS} calcium-independent cell-cell adhesion endoplasmic reticulum, integral to membrane, plasma membrane, tight junction identical protein binding, structural molecule activity Human UniProtKB:Q9Z0G9 CLDND1 UniProtKB UniProtKB {GO:0016324=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q9NY35 Claudin domain-containing protein 1 protein 20130413 {GO:0016324=IEA, GO:0016021=IEA} apical plasma membrane, integral to membrane Human UniProtKB-KW:KW-0812 CLEC11A HPA UniProtKB {GO:0005813=GO_REF:0000052, GO:0008284=PMID:11920266, GO:0005737=GO_REF:0000039, GO:0030246=PMID:9705843, GO:0005576=PMID:9442024, GO:0008083=PMID:11920266} Q9Y240 C-type lectin domain family 11 member A protein 20110516 {GO:0005813=IDA, GO:0008284=IDA, GO:0005737=IEA, GO:0030246=NAS, GO:0005576=IDA, GO:0008083=IDA} positive regulation of cell proliferation centrosome, cytoplasm, extracellular region carbohydrate binding, growth factor activity Human CLEC16A null null {} null null null null {} null null null CLEC17A UniProtKB UniProtKB {GO:0009986=PMID:19419970, GO:0042806=PMID:19419970, GO:0016021=GO_REF:0000037, GO:0005537=PMID:19419970, GO:0046872=GO_REF:0000037} Q6ZS10 C-type lectin domain family 17, member A protein 20100517 {GO:0009986=IDA, GO:0042806=IDA, GO:0016021=IEA, GO:0005537=IDA, GO:0046872=IEA} cell surface, integral to membrane fucose binding, mannose binding, metal ion binding Human CLEC18C UniProtKB UniProtKB {GO:0030246=GO_REF:0000002, GO:0005576=GO_REF:0000039} Q8NCF0 C-type lectin domain family 18 member C protein 20130413 {GO:0030246=IEA, GO:0005576=IEA} extracellular region carbohydrate binding Human UniProtKB-SubCell:SL-0243 CLEC1A PINC UniProtKB {GO:0005622=PMID:10671229, GO:0005887=PMID:10671229, GO:0030246=GO_REF:0000002, GO:0006952=PMID:10671229, GO:0007166=PMID:10671229, GO:0004888=PMID:10671229} Q8NC01 C-type lectin domain family 1 member A protein 20061106 {GO:0005622=TAS, GO:0005887=TAS, GO:0030246=IEA, GO:0006952=TAS, GO:0007166=TAS, GO:0004888=TAS} cell surface receptor signaling pathway, defense response integral to plasma membrane, intracellular carbohydrate binding, transmembrane signaling receptor activity Human CLEC1B PINC UniProtKB {GO:0005515=PMID:19785988, GO:0005887=GO_REF:0000019, GO:0030246=GO_REF:0000002, GO:0006952=PMID:10671229, GO:0007166=PMID:10671229, GO:0004888=PMID:10671229} Q9P126 C-type lectin domain family 1 member B protein 20030904 {GO:0005515=IPI, GO:0005887=IEA, GO:0030246=IEA, GO:0006952=TAS, GO:0007166=TAS, GO:0004888=TAS} cell surface receptor signaling pathway, defense response integral to plasma membrane carbohydrate binding, protein binding, transmembrane signaling receptor activity Human CLEC2A UniProtKB UniProtKB {GO:0005515=PMID:20194751, GO:0005886=GO_REF:0000039, GO:0042267=PMID:20194751, GO:0030246=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0042803=PMID:20194751} Q6UVW9 C-type lectin domain family 2 member A protein 20101217 {GO:0005515=IPI, GO:0005886=IEA, GO:0042267=TAS, GO:0030246=IEA, GO:0016021=IEA, GO:0042803=IDA} natural killer cell mediated cytotoxicity integral to membrane, plasma membrane carbohydrate binding, protein binding, protein homodimerization activity Human CLEC2B PINC UniProtKB {GO:0005887=PMID:9038101, GO:0030246=GO_REF:0000002} Q92478 C-type lectin domain family 2 member B protein 20030904 {GO:0005887=TAS, GO:0030246=IEA} integral to plasma membrane carbohydrate binding Human CLEC2D PINC UniProtKB {GO:0016020=PMID:10541800, GO:0009986=PMID:20843815, GO:0005887=PMID:10541800, GO:0005783=PMID:20843815, GO:0030246=GO_REF:0000002, GO:0007166=PMID:10541800, GO:0004888=PMID:10541800} Q9UHP7 C-type lectin domain family 2 member D protein 20030904 {GO:0016020=TAS, GO:0009986=IDA, GO:0005887=TAS, GO:0005783=IDA, GO:0030246=IEA, GO:0007166=TAS, GO:0004888=TAS} cell surface receptor signaling pathway cell surface, endoplasmic reticulum, integral to plasma membrane, membrane carbohydrate binding, transmembrane signaling receptor activity Human CLEC2L UniProtKB UniProtKB {GO:0030246=GO_REF:0000002, GO:0016021=GO_REF:0000037} P0C7M8 C-type lectin domain family 2 member L protein 20130413 {GO:0030246=IEA, GO:0016021=IEA} integral to membrane carbohydrate binding Human UniProtKB-KW:KW-0812 CLEC3B BHF-UCL UniProtKB {GO:0031012=PMID:22261194, GO:0005737=PMID:7798325, GO:0001501=GO_REF:0000019, GO:0001503=PMID:7798325, GO:0010756=GO_REF:0000024, GO:0005509=PMID:9786936, GO:0030246=GO_REF:0000002, GO:0005576=PMID:14718574, GO:0030282=PMID:7589422, GO:0008201=PMID:10727405, GO:0005615=PMID:7798325, GO:0036143=PMID:9786936} P05452 Tetranectin protein 20120228 {GO:0031012=ISS, GO:0005737=IDA, GO:0001501=IEA, GO:0001503=IEP, GO:0010756=ISS, GO:0005509=IDA, GO:0030246=IEA, GO:0005576=NAS, GO:0030282=IEP, GO:0008201=IDA, GO:0005615=IDA, GO:0036143=IPI} bone mineralization, ossification, positive regulation of plasminogen activation, skeletal system development cytoplasm, extracellular matrix, extracellular region, extracellular space calcium ion binding, carbohydrate binding, heparin binding, kringle domain binding colocalizes_with Human UniProtKB:F1SRC8 CLEC4A PINC UniProtKB {GO:0005887=PMID:10438934, GO:0045087=GO_REF:0000037, GO:0030246=GO_REF:0000002, GO:0007155=PMID:10438934, GO:0007166=PMID:10438934, GO:0004888=PMID:10438934} Q9UMR7 C-type lectin domain family 4 member A protein 20030904 {GO:0005887=TAS, GO:0045087=IEA, GO:0030246=IEA, GO:0007155=TAS, GO:0007166=TAS, GO:0004888=TAS} cell adhesion, cell surface receptor signaling pathway, innate immune response integral to plasma membrane carbohydrate binding, transmembrane signaling receptor activity Human CLEC4C UniProtKB UniProtKB {GO:0045087=GO_REF:0000037, GO:0030246=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q8WTT0 C-type lectin domain family 4 member C protein 20130413 {GO:0045087=IEA, GO:0030246=IEA, GO:0016021=IEA} innate immune response integral to membrane carbohydrate binding Human UniProtKB-KW:KW-0399 CLEC4F UniProtKB UniProtKB {GO:0030246=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0006897=GO_REF:0000037} Q8N1N0 C-type lectin domain family 4 member F protein 20130413 {GO:0030246=IEA, GO:0016021=IEA, GO:0006897=IEA} endocytosis integral to membrane carbohydrate binding Human UniProtKB-KW:KW-0812 CLEC4G UniProtKB UniProtKB {GO:0030246=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q6UXB4 C-type lectin domain family 4 member G protein 20130413 {GO:0030246=IEA, GO:0016021=IEA} integral to membrane carbohydrate binding Human UniProtKB-KW:KW-0812 CLEC4M PINC UniProtKB {GO:0019062=PMID:11337487, GO:0009988=PMID:11337487, GO:0046790=PMID:11337487, GO:0005576=GO_REF:0000039, GO:0046795=PMID:11337487, GO:0019079=PMID:11337487, GO:0005537=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0006897=GO_REF:0000037, GO:0035556=PMID:11337487, GO:0046968=PMID:11337487, GO:0005737=PMID:11337487, GO:0030369=PMID:11257134, GO:0016020=PMID:11337487, GO:0005887=PMID:10072769, GO:0019882=PMID:11337487, GO:0045087=GO_REF:0000037, GO:0019048=PMID:11337487, GO:0042605=PMID:11337487, GO:0007159=PMID:11337487, GO:0030246=PMID:11337487, GO:0004872=PMID:11257134} Q9H2X3 C-type lectin domain family 4 member M protein 20050308 {GO:0019062=TAS, GO:0009988=TAS, GO:0046790=TAS, GO:0005576=IEA, GO:0046795=TAS, GO:0019079=NAS, GO:0005537=IEA, GO:0046872=IEA, GO:0006897=IEA, GO:0035556=NAS, GO:0046968=NAS, GO:0005737=NAS, GO:0030369=NAS, GO:0016020=TAS, GO:0005887=TAS, GO:0019882=NAS, GO:0045087=IEA, GO:0019048=TAS, GO:0042605=NAS, GO:0007159=NAS, GO:0030246=NAS, GO:0004872=NAS} antigen processing and presentation, cell-cell recognition, endocytosis, innate immune response, intracellular signal transduction, intracellular virion transport, leukocyte cell-cell adhesion, peptide antigen transport, viral attachment to host cell, viral genome replication, virus-host interaction cytoplasm, extracellular region, integral to plasma membrane, membrane ICAM-3 receptor activity, carbohydrate binding, mannose binding, metal ion binding, peptide antigen binding, receptor activity, virion binding Human CLEC5A GOC UniProtKB {GO:0043066=GO_REF:0000024, GO:0009986=GO_REF:0000024, GO:0005886=Reactome:REACT_147800, GO:0050715=GO_REF:0000019, GO:0009615=PMID:18496526, GO:0007165=PMID:10449773, GO:0006968=PMID:10449773, GO:0002076=GO_REF:0000024, GO:0001618=PMID:18496526, GO:0005887=PMID:10449773, GO:0019048=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0030246=GO_REF:0000002} Q9NY25 C-type lectin domain family 5 member A protein 20130413 {GO:0043066=ISS, GO:0009986=ISS, GO:0005886=TAS, GO:0050715=IEA, GO:0009615=IDA, GO:0007165=TAS, GO:0006968=TAS, GO:0002076=ISS, GO:0001618=IDA, GO:0005887=TAS, GO:0019048=IEA, GO:0045087=TAS, GO:0030246=IEA} cellular defense response, innate immune response, negative regulation of apoptotic process, osteoblast development, positive regulation of cytokine secretion, response to virus, signal transduction, virus-host interaction cell surface, integral to plasma membrane, plasma membrane carbohydrate binding, viral receptor activity Human CLEC7A GOC UniProtKB {GO:0042287=PMID:11567029, GO:0008037=PMID:11567029, GO:0005886=GO_REF:0000039, GO:0042832=PMID:11567029, GO:0006910=PMID:11567029, GO:0046872=GO_REF:0000037, GO:0002221=PMID:11567029, GO:0042110=PMID:11567029, GO:0005737=GO_REF:0000039, GO:0009756=PMID:11567029, GO:0006954=GO_REF:0000037, GO:0045087=GO_REF:0000037, GO:0030246=PMID:11567029, GO:0016021=PMID:11567029, GO:0008329=PMID:11567029} Q9BXN2 C-type lectin domain family 7 member A protein 20130413 {GO:0042287=NAS, GO:0008037=IDA, GO:0005886=IEA, GO:0042832=NAS, GO:0006910=IDA, GO:0046872=IEA, GO:0002221=IDA, GO:0042110=TAS, GO:0005737=IEA, GO:0009756=TAS, GO:0006954=IEA, GO:0045087=IEA, GO:0030246=IDA, GO:0016021=TAS, GO:0008329=IDA} T cell activation, carbohydrate mediated signaling, cell recognition, defense response to protozoan, inflammatory response, innate immune response, pattern recognition receptor signaling pathway, phagocytosis, recognition cytoplasm, integral to membrane, plasma membrane MHC protein binding, carbohydrate binding, metal ion binding, pattern recognition receptor activity Human CLGN PINC UniProtKB {GO:0007338=PMID:9177349, GO:0006461=GO_REF:0000019, GO:0005783=PMID:9177349, GO:0006457=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0005635=GO_REF:0000019, GO:0051082=GO_REF:0000002, GO:0007339=GO_REF:0000019} O14967 Calmegin protein 20030904 {GO:0007338=TAS, GO:0006461=IEA, GO:0005783=TAS, GO:0006457=IEA, GO:0005509=IEA, GO:0005789=IEA, GO:0016021=IEA, GO:0005635=IEA, GO:0051082=IEA, GO:0007339=IEA} binding of sperm to zona pellucida, protein complex assembly, protein folding, single fertilization endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, nuclear envelope calcium ion binding, unfolded protein binding Human CLIC1 BHF-UCL UniProtKB {GO:0005515=PMID:12681486, GO:0006821=PMID:9139710, GO:0048471=PMID:12681486, GO:0031965=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0005247=GO_REF:0000002, GO:0034707=GO_REF:0000037, GO:0051881=GO_REF:0000019, GO:0005634=PMID:16130169, GO:0005635=PMID:9139710, GO:0005254=PMID:9139710, GO:0045669=GO_REF:0000019, GO:0005903=PMID:10793131, GO:0005739=GO_REF:0000019, GO:0007165=PMID:16130169, GO:0005737=PMID:10793131} O00299 Chloride intracellular channel protein 1 protein 20130215 {GO:0005515=IPI, GO:0006821=IDA, GO:0048471=IDA, GO:0031965=IEA, GO:0005886=IEA, GO:0005247=IEA, GO:0034707=IEA, GO:0051881=IEA, GO:0005634=TAS, GO:0005635=IDA, GO:0005254=IDA, GO:0045669=IEA, GO:0005903=TAS, GO:0005739=IEA, GO:0007165=TAS, GO:0005737=IDA} chloride transport, positive regulation of osteoblast differentiation, regulation of mitochondrial membrane potential, signal transduction brush border, chloride channel complex, cytoplasm, mitochondrion, nuclear envelope, nuclear membrane, nucleus, perinuclear region of cytoplasm, plasma membrane chloride channel activity, protein binding, voltage-gated chloride channel activity Human CLIC2 BHF-UCL UniProtKB {GO:0005515=PMID:12681486, GO:0005247=GO_REF:0000002, GO:0034707=GO_REF:0000037, GO:0051099=PMID:15916532, GO:0010881=PMID:15147738, GO:0005634=PMID:16130169, GO:0004364=PMID:15147738, GO:0005254=PMID:9339381, GO:0005622=GO_REF:0000054, GO:0004602=PMID:15147738, GO:0007165=PMID:16130169, GO:0005737=PMID:15916532, GO:0010880=PMID:15916532, GO:0060315=PMID:15916532, GO:0006810=PMID:9339381} O15247 Chloride intracellular channel protein 2 protein 20130215 {GO:0005515=IPI, GO:0005247=IEA, GO:0034707=IEA, GO:0051099=IDA, GO:0010881=IC, GO:0005634=TAS, GO:0004364=IDA, GO:0005254=TAS, GO:0005622=IDA, GO:0004602=IDA, GO:0007165=TAS, GO:0005737=IDA, GO:0010880=IDA, GO:0060315=IDA, GO:0006810=TAS} negative regulation of ryanodine-sensitive calcium-release channel activity, positive regulation of binding, regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion, regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum, signal transduction, transport chloride channel complex, cytoplasm, intracellular, nucleus chloride channel activity, glutathione peroxidase activity, glutathione transferase activity, protein binding, voltage-gated chloride channel activity Human UniProtKB:P0DI81 CLIC3 HPA UniProtKB {GO:0005515=PMID:9880541, GO:0007165=PMID:9880541, GO:0006821=PMID:9880541, GO:0005737=PMID:9880541, GO:0016020=GO_REF:0000002, GO:0005247=GO_REF:0000002, GO:0034707=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0005254=PMID:9880541} Q5SQ17 Chloride intracellular channel protein 3 protein 20080205 {GO:0005515=IPI, GO:0007165=TAS, GO:0006821=IMP, GO:0005737=IDA, GO:0016020=IEA, GO:0005247=IEA, GO:0034707=IEA, GO:0005634=IDA, GO:0005254=IMP} chloride transport, signal transduction chloride channel complex, cytoplasm, membrane, nucleus chloride channel activity, protein binding, voltage-gated chloride channel activity Human CLIC4 HPA UniProtKB {GO:0005515=PMID:12163479, GO:0006821=PMID:10793131, GO:0048471=PMID:14569596, GO:0005886=PMID:19776349, GO:0035088=PMID:14569596, GO:0061299=GO_REF:0000019, GO:0015629=PMID:12163372, GO:0005254=PMID:9295337, GO:0030154=PMID:12163372, GO:0016363=PMID:14569596, GO:0005829=PMID:19776349, GO:0005622=GO_REF:0000054, GO:0005739=PMID:14569596, GO:0005737=GO_REF:0000052, GO:0035264=GO_REF:0000019, GO:0007035=GO_REF:0000019, GO:0005911=PMID:14569596, GO:0015630=PMID:14569596, GO:0071277=PMID:17636002, GO:0030659=GO_REF:0000039, GO:0005773=GO_REF:0000019, GO:0030336=PMID:12163372, GO:0005813=PMID:14569596, GO:0009986=PMID:14569596, GO:0005247=GO_REF:0000002, GO:0034707=GO_REF:0000037, GO:0030496=PMID:14569596, GO:0045177=PMID:14569596, GO:0001525=GO_REF:0000019, GO:0009566=GO_REF:0000019, GO:0005902=PMID:14569596, GO:0051493=PMID:14569596, GO:0030216=PMID:17636002, GO:0001886=GO_REF:0000019, GO:0048754=GO_REF:0000019} Q9Y696 Chloride intracellular channel protein 4 protein 20080818 {GO:0005515=IPI, GO:0006821=NAS, GO:0048471=IDA, GO:0005886=IDA, GO:0035088=NAS, GO:0061299=IEA, GO:0015629=TAS, GO:0005254=TAS, GO:0030154=TAS, GO:0016363=IDA, GO:0005829=IDA, GO:0005622=IDA, GO:0005739=IDA, GO:0005737=IDA, GO:0035264=IEA, GO:0007035=IEA, GO:0005911=IDA, GO:0015630=IDA, GO:0071277=IMP, GO:0030659=IEA, GO:0005773=IEA, GO:0030336=IDA, GO:0005813=IDA, GO:0009986=IDA, GO:0005247=IEA, GO:0034707=IEA, GO:0030496=IDA, GO:0045177=IDA, GO:0001525=IEA, GO:0009566=IEA, GO:0005902=IDA, GO:0051493=NAS, GO:0030216=IMP, GO:0001886=IEA, GO:0048754=IEA} angiogenesis, branching morphogenesis of an epithelial tube, cell differentiation, cellular response to calcium ion, chloride transport, endothelial cell morphogenesis, establishment or maintenance of apical/basal cell polarity, fertilization, keratinocyte differentiation, multicellular organism growth, negative regulation of cell migration, regulation of cytoskeleton organization, retina vasculature morphogenesis in camera-type eye, vacuolar acidification actin cytoskeleton, apical part of cell, cell surface, cell-cell junction, centrosome, chloride channel complex, cytoplasm, cytoplasmic vesicle membrane, cytosol, intracellular, microtubule cytoskeleton, microvillus, midbody, mitochondrion, nuclear matrix, perinuclear region of cytoplasm, plasma membrane, vacuole chloride channel activity, protein binding, voltage-gated chloride channel activity Human CLIC5 PINC UniProtKB {GO:0005515=PMID:10793131, GO:0006821=PMID:10793131, GO:0007565=PMID:10793131, GO:0005794=GO_REF:0000039, GO:0005815=GO_REF:0000039, GO:0005247=GO_REF:0000002, GO:0007605=GO_REF:0000019, GO:0034707=GO_REF:0000037, GO:0002024=GO_REF:0000019, GO:0060088=GO_REF:0000019, GO:0032420=GO_REF:0000019, GO:0015629=PMID:10793131, GO:0008104=GO_REF:0000019, GO:0006810=PMID:10793131, GO:0050885=GO_REF:0000019, GO:0005938=GO_REF:0000039} Q9NZA1 Chloride intracellular channel protein 5 protein 20030904 {GO:0005515=IPI, GO:0006821=IDA, GO:0007565=TAS, GO:0005794=IEA, GO:0005815=IEA, GO:0005247=IEA, GO:0007605=IEA, GO:0034707=IEA, GO:0002024=IEA, GO:0060088=IEA, GO:0032420=IEA, GO:0015629=IDA, GO:0008104=IEA, GO:0006810=NAS, GO:0050885=IEA, GO:0005938=IEA} auditory receptor cell stereocilium organization, chloride transport, diet induced thermogenesis, female pregnancy, neuromuscular process controlling balance, protein localization, sensory perception of sound, transport Golgi apparatus, actin cytoskeleton, cell cortex, chloride channel complex, microtubule organizing center, stereocilium protein binding, voltage-gated chloride channel activity Human CLIC6 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0031749=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0005247=GO_REF:0000002, GO:0034707=GO_REF:0000037, GO:0008022=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0031751=GO_REF:0000019, GO:0031750=GO_REF:0000019} Q96NY7 Chloride intracellular channel protein 6 protein 20130413 {GO:0005737=IEA, GO:0031749=IEA, GO:0005886=IEA, GO:0005247=IEA, GO:0034707=IEA, GO:0008022=IEA, GO:0042803=IEA, GO:0031751=IEA, GO:0031750=IEA} chloride channel complex, cytoplasm, plasma membrane D2 dopamine receptor binding, D3 dopamine receptor binding, D4 dopamine receptor binding, protein C-terminus binding, protein homodimerization activity, voltage-gated chloride channel activity Human UniProtKB-SubCell:SL-0039 CLINT1 BHF-UCL UniProtKB {GO:0005515=PMID:12429846, GO:0048471=GO_REF:0000039, GO:0005794=PMID:10942595, GO:0016020=GO_REF:0000039, GO:0030276=PMID:12429846, GO:0030136=GO_REF:0000039, GO:0006892=Reactome:REACT_11235, GO:0016044=Reactome:REACT_11123, GO:0005829=Reactome:REACT_19237, GO:0008289=GO_REF:0000037, GO:0006897=GO_REF:0000037} Q14677 Clathrin interactor 1 protein 20110126 {GO:0005515=IPI, GO:0048471=IEA, GO:0005794=IDA, GO:0016020=IEA, GO:0030276=IPI, GO:0030136=IEA, GO:0006892=TAS, GO:0016044=TAS, GO:0005829=TAS, GO:0008289=IEA, GO:0006897=IEA} cellular membrane organization, endocytosis, post-Golgi vesicle-mediated transport Golgi apparatus, clathrin-coated vesicle, cytosol, membrane, perinuclear region of cytoplasm clathrin binding, lipid binding, protein binding Human UniProtKB:Q9UJY4 CLIP1 HPA UniProtKB {GO:0005515=PMID:17828275, GO:0008017=PMID:17889670, GO:0005882=PMID:1600942, GO:0000236=Reactome:REACT_682, GO:0005881=GO_REF:0000019, GO:0001578=PMID:17889670, GO:0035371=PMID:12433698, GO:0042803=PMID:15928712, GO:0046872=PMID:15928712, GO:0005829=Reactome:REACT_150414, GO:0044354=PMID:12433698, GO:0005737=GO_REF:0000052, GO:0015631=PMID:17889670, GO:0051010=PMID:12433698, GO:0015630=PMID:17889670, GO:0000087=Reactome:REACT_910, GO:0006810=GO_REF:0000037, GO:0030659=GO_REF:0000039, GO:0031116=PMID:17889670, GO:0005813=PMID:21399614, GO:0005874=GO_REF:0000024, GO:0003676=GO_REF:0000002, GO:0001726=GO_REF:0000039, GO:0007067=PMID:15928712, GO:0000776=PMID:15928712, GO:0008270=PMID:17828275, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0005768=PMID:1356075} P30622 CAP-Gly domain-containing linker protein 1 protein 20111111 {GO:0005515=IPI, GO:0008017=IDA, GO:0005882=TAS, GO:0000236=TAS, GO:0005881=IEA, GO:0001578=IMP, GO:0035371=IDA, GO:0042803=TAS, GO:0046872=NAS, GO:0005829=TAS, GO:0044354=IDA, GO:0005737=IDA, GO:0015631=IDA, GO:0051010=IDA, GO:0015630=IMP, GO:0000087=TAS, GO:0006810=IEA, GO:0030659=IEA, GO:0031116=IMP, GO:0005813=IDA, GO:0005874=ISS, GO:0003676=IEA, GO:0001726=IEA, GO:0007067=TAS, GO:0000776=TAS, GO:0008270=IDA, GO:0000278=TAS, GO:0000090=TAS, GO:0005768=TAS} M phase of mitotic cell cycle, microtubule bundle formation, mitosis, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, positive regulation of microtubule polymerization, transport centrosome, cytoplasm, cytoplasmic microtubule, cytoplasmic vesicle membrane, cytosol, endosome, intermediate filament, kinetochore, macropinosome, microtubule, microtubule cytoskeleton, microtubule plus end, ruffle metal ion binding, microtubule binding, microtubule plus-end binding, nucleic acid binding, protein binding, protein homodimerization activity, tubulin binding, zinc ion binding Human CLIP2 PINC UniProtKB {GO:0005881=GO_REF:0000019, GO:0005875=PMID:9799601} Q9UDT6 CAP-Gly domain-containing linker protein 2 protein 20061106 {GO:0005881=IEA, GO:0005875=TAS} cytoplasmic microtubule, microtubule associated complex Human CLIP3 UniProtKB UniProtKB {GO:0005802=GO_REF:0000024, GO:0008017=PMID:20052288, GO:0031115=PMID:15262990, GO:0043065=PMID:20052288, GO:0005795=GO_REF:0000039, GO:0005886=PMID:19139280, GO:0035594=PMID:20052288, GO:0018230=PMID:15262990, GO:0044091=PMID:11854307, GO:0032588=PMID:15262990, GO:0010828=GO_REF:0000024, GO:0045807=PMID:11854307, GO:0031901=PMID:11854307, GO:0001934=GO_REF:0000024, GO:0045444=GO_REF:0000024, GO:0045121=PMID:15262990, GO:0072321=PMID:20052288, GO:0055038=PMID:11854307, GO:0090004=GO_REF:0000024} Q96DZ5 CAP-Gly domain-containing linker protein 3 protein 20120613 {GO:0005802=ISS, GO:0008017=IMP, GO:0031115=IMP, GO:0043065=IMP, GO:0005795=IEA, GO:0005886=IDA, GO:0035594=IDA, GO:0018230=IMP, GO:0044091=IMP, GO:0032588=IMP, GO:0010828=ISS, GO:0045807=IMP, GO:0031901=IDA, GO:0001934=ISS, GO:0045444=ISS, GO:0045121=IDA, GO:0072321=IMP, GO:0055038=IDA, GO:0090004=ISS} chaperone-mediated protein transport, fat cell differentiation, membrane biogenesis, negative regulation of microtubule polymerization, peptidyl-L-cysteine S-palmitoylation, positive regulation of apoptotic process, positive regulation of endocytosis, positive regulation of establishment of protein localization to plasma membrane, positive regulation of glucose transport, positive regulation of protein phosphorylation Golgi stack, early endosome membrane, membrane raft, plasma membrane, recycling endosome membrane, trans-Golgi network, trans-Golgi network membrane ganglioside binding, microtubule binding Human UniProtKB:B9EHT4 CLIP4 null null {} null null null null {} null null null CLK1 PINC UniProtKB {GO:0005737=GO_REF:0000019, GO:0046777=GO_REF:0000019, GO:0018105=GO_REF:0000019, GO:0008283=PMID:1704889, GO:0004674=PMID:10480872, GO:0018107=GO_REF:0000019, GO:0043484=PMID:19168442, GO:0005634=GO_REF:0000039, GO:0018108=GO_REF:0000019, GO:0004712=GO_REF:0000003, GO:0004715=PMID:1825055, GO:0005524=GO_REF:0000037} P49759 Dual specificity protein kinase CLK1 protein 20030904 {GO:0005737=IEA, GO:0046777=IEA, GO:0018105=IEA, GO:0008283=TAS, GO:0004674=IDA, GO:0018107=IEA, GO:0043484=IMP, GO:0005634=IEA, GO:0018108=IEA, GO:0004712=IEA, GO:0004715=TAS, GO:0005524=IEA} cell proliferation, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, peptidyl-tyrosine phosphorylation, protein autophosphorylation, regulation of RNA splicing cytoplasm, nucleus ATP binding, non-membrane spanning protein tyrosine kinase activity, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity Human CLK2 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0045721=GO_REF:0000024, GO:0018108=GO_REF:0000019, GO:0005634=PMID:9637771, GO:0005524=GO_REF:0000037, GO:0046777=GO_REF:0000024, GO:0016607=GO_REF:0000039, GO:0004674=PMID:10480872, GO:0010212=PMID:20682768, GO:0004712=GO_REF:0000003, GO:0043484=PMID:9637771, GO:0006468=PMID:9637771, GO:0004713=GO_REF:0000019, GO:0032526=GO_REF:0000019} P49760 Dual specificity protein kinase CLK2 protein 20130415 {GO:0005515=IPI, GO:0045721=ISS, GO:0018108=IEA, GO:0005634=IDA, GO:0005524=IEA, GO:0046777=ISS, GO:0016607=IEA, GO:0004674=IDA, GO:0010212=IMP, GO:0004712=IEA, GO:0043484=IDA, GO:0006468=IDA, GO:0004713=IEA, GO:0032526=IEA} negative regulation of gluconeogenesis, peptidyl-tyrosine phosphorylation, protein autophosphorylation, protein phosphorylation, regulation of RNA splicing, response to ionizing radiation, response to retinoic acid nuclear speck, nucleus ATP binding, protein binding, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity, protein tyrosine kinase activity Human UniProtKB:P08621 CLK3 HPA UniProtKB {GO:0001669=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0018108=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0004672=GO_REF:0000002, GO:0046777=GO_REF:0000019, GO:0016607=GO_REF:0000039, GO:0004674=GO_REF:0000024, GO:0006468=PMID:9637771, GO:0004712=GO_REF:0000003, GO:0043484=PMID:9637771, GO:0045111=GO_REF:0000052, GO:0004713=GO_REF:0000019} P49761 Dual specificity protein kinase CLK3 protein 20120912 {GO:0001669=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0018108=IEA, GO:0005524=IEA, GO:0004672=IEA, GO:0046777=IEA, GO:0016607=IEA, GO:0004674=ISS, GO:0006468=IDA, GO:0004712=IEA, GO:0043484=IDA, GO:0045111=IDA, GO:0004713=IEA} peptidyl-tyrosine phosphorylation, protein autophosphorylation, protein phosphorylation, regulation of RNA splicing acrosomal vesicle, intermediate filament cytoskeleton, nuclear speck, nucleolus, nucleus ATP binding, protein kinase activity, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity, protein tyrosine kinase activity Human CLK4 UniProtKB UniProtKB {GO:0046777=GO_REF:0000019, GO:0004674=GO_REF:0000024, GO:0043484=PMID:19168442, GO:0005634=GO_REF:0000039, GO:0018108=GO_REF:0000019, GO:0004712=GO_REF:0000003, GO:0004713=GO_REF:0000019, GO:0005524=GO_REF:0000037} Q9HAZ1 Dual specificity protein kinase CLK4 protein 20110904 {GO:0046777=IEA, GO:0004674=ISS, GO:0043484=IMP, GO:0005634=IEA, GO:0018108=IEA, GO:0004712=IEA, GO:0004713=IEA, GO:0005524=IEA} peptidyl-tyrosine phosphorylation, protein autophosphorylation, regulation of RNA splicing nucleus ATP binding, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity, protein tyrosine kinase activity Human UniProtKB:O35493 CLMN ENSEMBL UniProtKB {GO:0005737=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0031175=GO_REF:0000019} Q96JQ2 Calmin protein 20130413 {GO:0005737=IEA, GO:0008285=IEA, GO:0003779=IEA, GO:0016021=IEA, GO:0031175=IEA} negative regulation of cell proliferation, neuron projection development cytoplasm, integral to membrane actin binding Human Ensembl:ENSMUSP00000105563 CLN3 InterPro UniProtKB {GO:0005802=PMID:15240864, GO:0005515=PMID:22261744, GO:0008219=GO_REF:0000037, GO:0016242=GO_REF:0000024, GO:0005765=PMID:9384607, GO:0005764=PMID:10924275, GO:0030163=PMID:10740217, GO:0043524=GO_REF:0000024, GO:0007034=GO_REF:0000033, GO:0006457=PMID:8980123, GO:0047496=PMID:22261744, GO:0016485=GO_REF:0000024, GO:0050885=GO_REF:0000024, GO:0008306=GO_REF:0000024, GO:0006684=PMID:15240864, GO:0005794=PMID:15240864, GO:0005795=PMID:15240864, GO:0043086=GO_REF:0000024, GO:0006898=PMID:15471887, GO:0006681=PMID:15240864, GO:0035235=GO_REF:0000024, GO:0045121=PMID:15240864, GO:0035752=PMID:10924275, GO:0051082=PMID:8980123, GO:0007042=PMID:11722572, GO:0001508=GO_REF:0000024, GO:0015809=PMID:16251196, GO:0007040=GO_REF:0000024, GO:0016044=GO_REF:0000024, GO:0006678=PMID:15240864, GO:0043005=PMID:10332042, GO:0005886=PMID:15240864, GO:0001575=PMID:15240864, GO:0005783=PMID:10191111, GO:0006672=PMID:15240864, GO:0005634=PMID:10191116, GO:0030176=PMID:12706816, GO:0005739=PMID:8980123, GO:0005737=PMID:10191116, GO:0000046=GO_REF:0000024, GO:0042987=PMID:10924275, GO:0006520=GO_REF:0000024, GO:0043066=PMID:15240864, GO:0005776=GO_REF:0000024, GO:0005770=PMID:22261744, GO:0051480=GO_REF:0000024, GO:0016236=PMID:9949212, GO:0008021=PMID:11590129, GO:0045861=GO_REF:0000024, GO:0000139=PMID:10191111, GO:0016020=GO_REF:0000002, GO:0005901=PMID:15240864, GO:0016021=PMID:10191112, GO:0005769=PMID:15240864, GO:0042133=GO_REF:0000024} Q9UBH5 Battenin protein 20130413 {GO:0005802=IDA, GO:0005515=IPI, GO:0008219=IEA, GO:0016242=ISS, GO:0005765=IDA, GO:0005764=IDA, GO:0030163=NAS, GO:0043524=ISS, GO:0007034=IBA, GO:0006457=TAS, GO:0047496=IMP, GO:0016485=ISS, GO:0050885=ISS, GO:0008306=ISS, GO:0006684=IMP, GO:0005794=IDA, GO:0005795=IDA, GO:0043086=ISS, GO:0006898=IMP, GO:0006681=IMP, GO:0035235=ISS, GO:0045121=IDA, GO:0035752=IDA, GO:0051082=TAS, GO:0007042=IMP, GO:0001508=ISS, GO:0015809=IDA, GO:0007040=ISS, GO:0016044=ISS, GO:0006678=IMP, GO:0043005=IDA, GO:0005886=IDA, GO:0001575=IMP, GO:0005783=IDA, GO:0006672=IDA, GO:0005634=IDA, GO:0030176=IDA, GO:0005739=TAS, GO:0005737=IDA, GO:0000046=ISS, GO:0042987=IDA, GO:0006520=ISS, GO:0043066=IMP, GO:0005776=ISS, GO:0005770=IDA, GO:0051480=ISS, GO:0016236=NAS, GO:0008021=IDA, GO:0045861=ISS, GO:0000139=IDA, GO:0016020=IEA, GO:0005901=IDA, GO:0016021=IDA, GO:0005769=IDA, GO:0042133=ISS} amyloid precursor protein catabolic process, arginine transport, associative learning, autophagic vacuole fusion, cell death, cellular amino acid metabolic process, cellular membrane organization, ceramide metabolic process, cytosolic calcium ion homeostasis, galactosylceramide metabolic process, globoside metabolic process, glucosylceramide metabolic process, ionotropic glutamate receptor signaling pathway, lysosomal lumen acidification, lysosomal lumen pH elevation, lysosome organization, macroautophagy, negative regulation of apoptotic process, negative regulation of catalytic activity, negative regulation of macroautophagy, negative regulation of neuron apoptotic process, negative regulation of proteolysis, neuromuscular process controlling balance, neurotransmitter metabolic process, protein catabolic process, protein folding, protein processing, receptor-mediated endocytosis, regulation of action potential, sphingomyelin metabolic process, vacuolar transport, vesicle transport along microtubule Golgi apparatus, Golgi membrane, Golgi stack, autophagic vacuole, caveola, cytoplasm, early endosome, endoplasmic reticulum, integral to endoplasmic reticulum membrane, integral to membrane, late endosome, lysosomal membrane, lysosome, membrane, membrane raft, mitochondrion, neuron projection, nucleus, plasma membrane, synaptic vesicle, trans-Golgi network protein binding, unfolded protein binding Human InterPro:IPR003492 CLN5 UniProtKB UniProtKB {GO:0005515=PMID:12134079, GO:0008219=GO_REF:0000037, GO:0005775=GO_REF:0000019, GO:0048471=PMID:10992246, GO:0070085=PMID:16399764, GO:0005794=PMID:12134079, GO:0005783=PMID:12134079, GO:0042551=PMID:10992246, GO:0005765=PMID:12134079, GO:0005537=PMID:16399764, GO:0005764=PMID:11971870, GO:0030163=PMID:10740217, GO:0007420=PMID:10992246, GO:0007042=PMID:11722572, GO:0016021=PMID:12134079, GO:0007601=GO_REF:0000019, GO:0006465=PMID:20052765, GO:0022008=PMID:10992246} O75503 Ceroid-lipofuscinosis neuronal protein 5 protein 20120628 {GO:0005515=IPI, GO:0008219=IEA, GO:0005775=IEA, GO:0048471=IDA, GO:0070085=IDA, GO:0005794=IDA, GO:0005783=IDA, GO:0042551=NAS, GO:0005765=IDA, GO:0005537=IDA, GO:0005764=IDA, GO:0030163=NAS, GO:0007420=IEP, GO:0007042=IMP, GO:0016021=IDA, GO:0007601=IEA, GO:0006465=IDA, GO:0022008=IEP} brain development, cell death, glycosylation, lysosomal lumen acidification, neurogenesis, neuron maturation, protein catabolic process, signal peptide processing, visual perception Golgi apparatus, endoplasmic reticulum, integral to membrane, lysosomal membrane, lysosome, perinuclear region of cytoplasm, vacuolar lumen mannose binding, protein binding Human CLN6 UniProtKB UniProtKB {GO:0005515=PMID:19235893, GO:0044265=GO_REF:0000019, GO:0008219=GO_REF:0000037, GO:0005783=PMID:15265688, GO:0031987=GO_REF:0000019, GO:0045862=PMID:15010453, GO:0042803=PMID:15010453, GO:0030163=PMID:10740217, GO:0005789=GO_REF:0000039, GO:0001573=PMID:16857350, GO:0005788=PMID:15010453, GO:0016021=PMID:11727201, GO:0007042=PMID:11722572, GO:0030203=PMID:16857350, GO:0007601=GO_REF:0000019, GO:0008203=PMID:16857350} Q9NWW5 Ceroid-lipofuscinosis neuronal protein 6 protein 20120615 {GO:0005515=IPI, GO:0044265=IEA, GO:0008219=IEA, GO:0005783=IDA, GO:0031987=IEA, GO:0045862=IMP, GO:0042803=IDA, GO:0030163=NAS, GO:0005789=IEA, GO:0001573=IMP, GO:0005788=IDA, GO:0016021=NAS, GO:0007042=IMP, GO:0030203=IMP, GO:0007601=IEA, GO:0008203=IMP} cell death, cellular macromolecule catabolic process, cholesterol metabolic process, ganglioside metabolic process, glycosaminoglycan metabolic process, locomotion involved in locomotory behavior, lysosomal lumen acidification, positive regulation of proteolysis, protein catabolic process, visual perception endoplasmic reticulum, endoplasmic reticulum lumen, endoplasmic reticulum membrane, integral to membrane protein binding, protein homodimerization activity Human UniProtKB:Q16555 CLN8 UniProtKB UniProtKB {GO:0008361=GO_REF:0000019, GO:0008219=GO_REF:0000037, GO:0060041=GO_REF:0000019, GO:0005783=PMID:10861296, GO:0006672=PMID:16086686, GO:0045494=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0030163=PMID:10740217, GO:0050881=GO_REF:0000019, GO:0033116=GO_REF:0000039, GO:0050884=GO_REF:0000019, GO:0007628=GO_REF:0000019, GO:0050885=GO_REF:0000019, GO:0046513=PMID:12151215, GO:0044257=GO_REF:0000019, GO:0008203=PMID:16086686, GO:0008306=GO_REF:0000019, GO:0008610=PMID:12151215, GO:0043066=GO_REF:0000019, GO:0021523=GO_REF:0000019, GO:0060052=GO_REF:0000019, GO:0005793=PMID:10861296, GO:0051348=GO_REF:0000019, GO:0045861=PMID:12151215, GO:0007399=PMID:10508524, GO:0006869=PMID:12151215, GO:0035176=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0007006=GO_REF:0000019, GO:0051935=GO_REF:0000019, GO:0016021=PMID:10861296, GO:0006644=PMID:16086686, GO:0007040=GO_REF:0000019, GO:0001306=GO_REF:0000019} Q9UBY8 Protein CLN8 protein 20060915 {GO:0008361=IEA, GO:0008219=IEA, GO:0060041=IEA, GO:0005783=IDA, GO:0006672=IMP, GO:0045494=IEA, GO:0005739=IEA, GO:0030163=NAS, GO:0050881=IEA, GO:0033116=IEA, GO:0050884=IEA, GO:0007628=IEA, GO:0050885=IEA, GO:0046513=NAS, GO:0044257=IEA, GO:0008203=IMP, GO:0008306=IEA, GO:0008610=NAS, GO:0043066=IEA, GO:0021523=IEA, GO:0060052=IEA, GO:0005793=IDA, GO:0051348=IEA, GO:0045861=NAS, GO:0007399=IMP, GO:0006869=NAS, GO:0035176=IEA, GO:0005789=IEA, GO:0007006=IEA, GO:0051935=IEA, GO:0016021=NAS, GO:0006644=IMP, GO:0007040=IEA, GO:0001306=IEA} L-glutamate uptake involved in synaptic transmission, adult walking behavior, age-dependent response to oxidative stress, associative learning, cell death, cellular protein catabolic process, ceramide biosynthetic process, ceramide metabolic process, cholesterol metabolic process, lipid biosynthetic process, lipid transport, lysosome organization, mitochondrial membrane organization, musculoskeletal movement, negative regulation of apoptotic process, negative regulation of proteolysis, negative regulation of transferase activity, nervous system development, neurofilament cytoskeleton organization, neuromuscular process controlling balance, neuromuscular process controlling posture, phospholipid metabolic process, photoreceptor cell maintenance, protein catabolic process, regulation of cell size, retina development in camera-type eye, social behavior, somatic motor neuron differentiation endoplasmic reticulum, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment, endoplasmic reticulum-Golgi intermediate compartment membrane, integral to membrane, mitochondrion Human CLNK UniProtKB UniProtKB {GO:0035556=PMID:10744659, GO:0005622=PMID:10744659, GO:0006955=PMID:10744659, GO:0005070=PMID:10744659, GO:0007169=GO_REF:0000019} Q7Z7G1 Cytokine-dependent hematopoietic cell linker protein 20010913 {GO:0035556=IDA, GO:0005622=NAS, GO:0006955=NAS, GO:0005070=NAS, GO:0007169=IEA} immune response, intracellular signal transduction, transmembrane receptor protein tyrosine kinase signaling pathway intracellular SH3/SH2 adaptor activity Human CLNS1A IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0006821=GO_REF:0000002, GO:0010467=Reactome:REACT_71, GO:0005886=PMID:9359436, GO:0016070=Reactome:REACT_21257, GO:0008015=PMID:9359436, GO:0005634=GO_REF:0000039, GO:0034660=Reactome:REACT_11052, GO:0000387=Reactome:REACT_11066, GO:0006884=GO_REF:0000002, GO:0005829=Reactome:REACT_10041, GO:0006810=PMID:7887970, GO:0005856=GO_REF:0000039} P54105 Methylosome subunit pICln protein 20130415 {GO:0005515=IPI, GO:0006821=IEA, GO:0010467=TAS, GO:0005886=TAS, GO:0016070=TAS, GO:0008015=TAS, GO:0005634=IEA, GO:0034660=TAS, GO:0000387=TAS, GO:0006884=IEA, GO:0005829=TAS, GO:0006810=TAS, GO:0005856=IEA} RNA metabolic process, blood circulation, cell volume homeostasis, chloride transport, gene expression, ncRNA metabolic process, spliceosomal snRNP assembly, transport cytoskeleton, cytosol, nucleus, plasma membrane protein binding Human UniProtKB:P62318 CLOCK HPA UniProtKB {GO:0001190=GO_REF:0000024, GO:0003700=GO_REF:0000024, GO:0000982=GO_REF:0000024, GO:0009648=PMID:10198158, GO:0005634=GO_REF:0000052, GO:0005829=Reactome:REACT_118740, GO:0043231=GO_REF:0000052, GO:0005737=GO_REF:0000019, GO:0045944=PMID:9576906, GO:0046983=GO_REF:0000002, GO:0004871=GO_REF:0000002, GO:0004402=GO_REF:0000003, GO:0005667=PMID:9576906, GO:0006355=GO_REF:0000024, GO:0006357=PMID:10198158, GO:0005694=PMID:21659603, GO:0005730=GO_REF:0000052, GO:0070888=PMID:18411297, GO:0000978=PMID:18411297, GO:0003677=GO_REF:0000038, GO:0071479=PMID:21659603, GO:0032922=GO_REF:0000024, GO:0007165=PMID:10198158, GO:0007623=PMID:10198158, GO:0000077=PMID:21659603} O15516 Circadian locomoter output cycles protein kaput protein 20101115 {GO:0001190=ISS, GO:0003700=ISS, GO:0000982=ISS, GO:0009648=TAS, GO:0005634=IDA, GO:0005829=TAS, GO:0043231=IDA, GO:0005737=IEA, GO:0045944=IGI, GO:0046983=IEA, GO:0004871=IEA, GO:0004402=IEA, GO:0005667=IPI, GO:0006355=ISS, GO:0006357=TAS, GO:0005694=IDA, GO:0005730=IDA, GO:0070888=IDA, GO:0000978=IDA, GO:0003677=IEA, GO:0071479=IDA, GO:0032922=ISS, GO:0007165=TAS, GO:0007623=TAS, GO:0000077=IMP} DNA damage checkpoint, cellular response to ionizing radiation, circadian regulation of gene expression, circadian rhythm, photoperiodism, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, signal transduction chromosome, cytoplasm, cytosol, intracellular membrane-bounded organelle, nucleolus, nucleus, transcription factor complex DNA binding, E-box binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription, histone acetyltransferase activity, protein dimerization activity, sequence-specific DNA binding transcription factor activity, signal transducer activity Human CLP1 Reactome UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0006388=PMID:17495927, GO:0030423=PMID:17495927, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0006366=Reactome:REACT_1366, GO:0031124=Reactome:REACT_1849, GO:0000214=PMID:17495927, GO:0005524=PMID:8896421, GO:0035087=PMID:17495927, GO:0046404=GO_REF:0000003, GO:0000398=Reactome:REACT_467, GO:0005654=Reactome:REACT_1935, GO:0051736=PMID:17495927, GO:0051733=PMID:17495927} Q92989 Polyribonucleotide 5'-hydroxyl-kinase Clp1 protein 20130213 {GO:0008380=TAS, GO:0006388=IDA, GO:0030423=IMP, GO:0010467=TAS, GO:0006369=TAS, GO:0006366=TAS, GO:0031124=TAS, GO:0000214=IDA, GO:0005524=TAS, GO:0035087=IDA, GO:0046404=IEA, GO:0000398=TAS, GO:0005654=TAS, GO:0051736=IDA, GO:0051733=IDA} RNA splicing, gene expression, mRNA 3'-end processing, mRNA splicing, via spliceosome, siRNA loading onto RISC involved in RNA interference, tRNA splicing, via endonucleolytic cleavage and ligation, targeting of mRNA for destruction involved in RNA interference, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter nucleoplasm, tRNA-intron endonuclease complex ATP binding, ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity, ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity, polydeoxyribonucleotide kinase activity Human CLPB UniProtKB UniProtKB {GO:0034605=PMID:2745427, GO:0005739=GO_REF:0000019, GO:0003674=GO_REF:0000015, GO:0017111=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0005524=GO_REF:0000037} Q9H078 Caseinolytic peptidase B protein homolog protein 20081219 {GO:0034605=IDA, GO:0005739=IEA, GO:0003674=ND, GO:0017111=IEA, GO:0005575=ND, GO:0005524=IEA} cellular response to heat cellular_component, mitochondrion ATP binding, molecular_function, nucleoside-triphosphatase activity Human CLPP HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005515=PMID:16115876, GO:0004252=GO_REF:0000002, GO:0005759=GO_REF:0000039, GO:0006508=GO_REF:0000037, GO:0008233=PMID:8543061, GO:0005524=GO_REF:0000037} Q16740 Putative ATP-dependent Clp protease proteolytic subunit, mitochondrial protein 20080205 {GO:0005739=IDA, GO:0005515=IPI, GO:0004252=IEA, GO:0005759=IEA, GO:0006508=IEA, GO:0008233=TAS, GO:0005524=IEA} proteolysis mitochondrial matrix, mitochondrion ATP binding, peptidase activity, protein binding, serine-type endopeptidase activity Human CLPS Reactome UniProtKB {GO:0006629=Reactome:REACT_602, GO:0016042=GO_REF:0000037, GO:0007603=Reactome:REACT_160125, GO:0044241=Reactome:REACT_9518, GO:0005576=Reactome:REACT_25240, GO:0044281=Reactome:REACT_111217, GO:0008047=GO_REF:0000002, GO:0001523=Reactome:REACT_24968} P04118 Colipase protein 20070202 {GO:0006629=TAS, GO:0016042=IEA, GO:0007603=TAS, GO:0044241=TAS, GO:0005576=TAS, GO:0044281=TAS, GO:0008047=IEA, GO:0001523=TAS} lipid catabolic process, lipid digestion, lipid metabolic process, phototransduction, visible light, retinoid metabolic process, small molecule metabolic process extracellular region enzyme activator activity Human CLPTM1 BHF-UCL UniProtKB {GO:0005515=PMID:21903422, GO:0005887=PMID:9828125, GO:0033081=GO_REF:0000024, GO:0007275=GO_REF:0000037, GO:0016021=GO_REF:0000038, GO:0030154=GO_REF:0000037, GO:0009897=GO_REF:0000024} O96005 Cleft lip and palate transmembrane protein 1 protein 20071212 {GO:0005515=IPI, GO:0005887=TAS, GO:0033081=ISS, GO:0007275=IEA, GO:0016021=IEA, GO:0030154=IEA, GO:0009897=ISS} cell differentiation, multicellular organismal development, regulation of T cell differentiation in thymus external side of plasma membrane, integral to membrane, integral to plasma membrane protein binding Human UniProtKB:Q8VBZ3 CLPTM1L UniProtKB UniProtKB {GO:0006915=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q96KA5 Cleft lip and palate transmembrane protein 1-like protein protein 20130413 {GO:0006915=IEA, GO:0016021=IEA} apoptotic process integral to membrane Human UniProtKB-KW:KW-0812 CLPX GOC UniProtKB {GO:0042645=PMID:18063578, GO:0005515=PMID:11923310, GO:0005743=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0005739=GO_REF:0000052, GO:0016504=PMID:16115876, GO:0010952=PMID:16115876, GO:0006457=GO_REF:0000002, GO:0009841=PMID:16115876, GO:0051603=PMID:16115876, GO:0004176=PMID:16115876, GO:0051082=GO_REF:0000002, GO:0016887=GO_REF:0000024} O76031 ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial protein 20130413 {GO:0042645=IDA, GO:0005515=IPI, GO:0005743=ISS, GO:0005730=IDA, GO:0005634=IDA, GO:0005524=ISS, GO:0046872=IEA, GO:0005739=IDA, GO:0016504=IDA, GO:0010952=IDA, GO:0006457=IEA, GO:0009841=IDA, GO:0051603=IDA, GO:0004176=IDA, GO:0051082=IEA, GO:0016887=ISS} positive regulation of peptidase activity, protein folding, proteolysis involved in cellular protein catabolic process mitochondrial endopeptidase Clp complex, mitochondrial inner membrane, mitochondrial nucleoid, mitochondrion, nucleolus, nucleus ATP binding, ATP-dependent peptidase activity, ATPase activity, metal ion binding, peptidase activator activity, protein binding, unfolded protein binding Human CLSPN IntAct UniProtKB {GO:0005515=PMID:18662541, GO:0010997=PMID:18662541, GO:0031572=PMID:18662541, GO:0006915=Reactome:REACT_578, GO:0003677=GO_REF:0000037, GO:0006921=Reactome:REACT_995, GO:0032147=PMID:16885022, GO:0006260=Reactome:REACT_6769, GO:0006281=GO_REF:0000037, GO:0018105=PMID:16885022, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_13652, GO:0000077=PMID:16963448, GO:0033314=PMID:16885022} Q9HAW4 Claspin protein 20130415 {GO:0005515=IPI, GO:0010997=IPI, GO:0031572=IDA, GO:0006915=TAS, GO:0003677=IEA, GO:0006921=TAS, GO:0032147=IDA, GO:0006260=TAS, GO:0006281=IEA, GO:0018105=IDA, GO:0000075=TAS, GO:0005654=TAS, GO:0000077=IMP, GO:0033314=IMP} DNA damage checkpoint, DNA repair, DNA replication, G2 DNA damage checkpoint, activation of protein kinase activity, apoptotic process, cell cycle checkpoint, cellular component disassembly involved in execution phase of apoptosis, mitotic DNA replication checkpoint, peptidyl-serine phosphorylation nucleoplasm DNA binding, anaphase-promoting complex binding, protein binding Human UniProtKB:Q9UM11 CLSTN1 UniProtKB UniProtKB {GO:0030054=GO_REF:0000037, GO:0000139=GO_REF:0000039, GO:0005886=GO_REF:0000037, GO:0045211=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0005576=GO_REF:0000019, GO:0042995=GO_REF:0000039, GO:0016021=GO_REF:0000038, GO:0007156=GO_REF:0000002} Q5SR54 Calsyntenin-1 protein 20130413 {GO:0030054=IEA, GO:0000139=IEA, GO:0005886=IEA, GO:0045211=IEA, GO:0005509=IEA, GO:0005789=IEA, GO:0005634=IEA, GO:0005576=IEA, GO:0042995=IEA, GO:0016021=IEA, GO:0007156=IEA} homophilic cell adhesion Golgi membrane, cell junction, cell projection, endoplasmic reticulum membrane, extracellular region, integral to membrane, nucleus, plasma membrane, postsynaptic membrane calcium ion binding Human UniProtKB-KW:KW-0812 CLSTN3 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0000139=GO_REF:0000039, GO:0045211=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000002} Q9BQT9 Calsyntenin-3 protein 20130413 {GO:0005886=IEA, GO:0000139=IEA, GO:0045211=IEA, GO:0005509=IEA, GO:0005789=IEA, GO:0016021=IEA, GO:0007156=IEA} homophilic cell adhesion Golgi membrane, endoplasmic reticulum membrane, integral to membrane, plasma membrane, postsynaptic membrane calcium ion binding Human UniProtKB-SubCell:SL-0039 CLTA BHF-UCL UniProtKB {GO:0042277=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0030132=GO_REF:0000002, GO:0005886=Reactome:REACT_120835, GO:0042059=Reactome:REACT_12484, GO:0006892=Reactome:REACT_11235, GO:0032588=Reactome:REACT_121003, GO:0006886=GO_REF:0000029, GO:0006897=GO_REF:0000019, GO:0030118=PMID:3267234, GO:0005829=Reactome:REACT_121003, GO:0019886=Reactome:REACT_121399, GO:0003674=GO_REF:0000015, GO:0007173=Reactome:REACT_9417, GO:0007411=Reactome:REACT_18266, GO:0005198=GO_REF:0000002, GO:0016023=GO_REF:0000024, GO:0030130=GO_REF:0000002, GO:0016192=GO_REF:0000002, GO:0030669=Reactome:REACT_121177, GO:0016044=Reactome:REACT_11123} P09496 Clathrin light chain A protein 20120517 {GO:0042277=IEA, GO:0048011=TAS, GO:0030132=IEA, GO:0005886=TAS, GO:0042059=TAS, GO:0006892=TAS, GO:0032588=TAS, GO:0006886=NAS, GO:0006897=IEA, GO:0030118=NAS, GO:0005829=TAS, GO:0019886=TAS, GO:0003674=ND, GO:0007173=TAS, GO:0007411=TAS, GO:0005198=IEA, GO:0016023=ISS, GO:0030130=IEA, GO:0016192=IEA, GO:0030669=TAS, GO:0016044=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, axon guidance, cellular membrane organization, endocytosis, epidermal growth factor receptor signaling pathway, intracellular protein transport, negative regulation of epidermal growth factor receptor signaling pathway, neurotrophin TRK receptor signaling pathway, post-Golgi vesicle-mediated transport, vesicle-mediated transport clathrin coat, clathrin coat of coated pit, clathrin coat of trans-Golgi network vesicle, clathrin-coated endocytic vesicle membrane, cytoplasmic membrane-bounded vesicle, cytosol, plasma membrane, trans-Golgi network membrane molecular_function, peptide binding, structural molecule activity Human UniProtKB:O08585 CLTB UniProtKB UniProtKB {GO:0005515=PMID:15533940, GO:0005802=GO_REF:0000019, GO:0042277=GO_REF:0000019, GO:0060170=GO_REF:0000019, GO:0030132=GO_REF:0000002, GO:0005198=GO_REF:0000002, GO:0030130=GO_REF:0000002, GO:0016192=GO_REF:0000002, GO:0006886=GO_REF:0000029, GO:0030118=GO_REF:0000024} P09497 Clathrin light chain B protein 20091109 {GO:0005515=IPI, GO:0005802=IEA, GO:0042277=IEA, GO:0060170=IEA, GO:0030132=IEA, GO:0005198=IEA, GO:0030130=IEA, GO:0016192=IEA, GO:0006886=NAS, GO:0030118=ISS} intracellular protein transport, vesicle-mediated transport cilium membrane, clathrin coat, clathrin coat of coated pit, clathrin coat of trans-Golgi network vesicle, trans-Golgi network peptide binding, protein binding, structural molecule activity Human UniProtKB:P08082 CLTC BHF-UCL UniProtKB {GO:0005515=PMID:12429846, GO:0042470=GO_REF:0000039, GO:0030132=GO_REF:0000002, GO:0030136=PMID:19478182, GO:0006892=Reactome:REACT_11235, GO:0005819=PMID:15858577, GO:0032588=Reactome:REACT_121003, GO:0006886=PMID:1765375, GO:0006898=PMID:15858577, GO:0005829=Reactome:REACT_121003, GO:0030118=PMID:1765375, GO:0031623=PMID:14985334, GO:0005739=GO_REF:0000019, GO:0033572=PMID:14985334, GO:0019886=Reactome:REACT_121399, GO:0007067=PMID:15858577, GO:0005198=PMID:1765375, GO:0030130=GO_REF:0000002, GO:0016192=GO_REF:0000002, GO:0030669=Reactome:REACT_121177, GO:0016044=Reactome:REACT_11123} Q00610 Clathrin heavy chain 1 protein 20100203 {GO:0005515=IPI, GO:0042470=IEA, GO:0030132=IEA, GO:0030136=IDA, GO:0006892=TAS, GO:0005819=IDA, GO:0032588=TAS, GO:0006886=NAS, GO:0006898=IMP, GO:0005829=TAS, GO:0030118=NAS, GO:0031623=IMP, GO:0005739=IEA, GO:0033572=IMP, GO:0019886=TAS, GO:0007067=IMP, GO:0005198=NAS, GO:0030130=IEA, GO:0016192=IEA, GO:0030669=TAS, GO:0016044=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, cellular membrane organization, intracellular protein transport, mitosis, post-Golgi vesicle-mediated transport, receptor internalization, receptor-mediated endocytosis, transferrin transport, vesicle-mediated transport clathrin coat, clathrin coat of coated pit, clathrin coat of trans-Golgi network vesicle, clathrin-coated endocytic vesicle membrane, clathrin-coated vesicle, cytosol, melanosome, mitochondrion, spindle, trans-Golgi network membrane protein binding, structural molecule activity Human CLTCL1 GOC UniProtKB {GO:0005802=PMID:19509056, GO:0005515=PMID:19478182, GO:0030132=GO_REF:0000002, GO:0030135=PMID:19509056, GO:0030136=PMID:19478182, GO:0005819=PMID:19509056, GO:0009653=PMID:8733128, GO:0006886=GO_REF:0000002, GO:0006898=PMID:19509056, GO:0007165=PMID:8844170, GO:0005905=PMID:19509056, GO:0007067=PMID:19509056, GO:0005198=GO_REF:0000002, GO:0046326=PMID:19478182, GO:0030130=GO_REF:0000002, GO:0004871=PMID:8844170, GO:0016192=GO_REF:0000002} P53675 Clathrin heavy chain 2 protein 20130413 {GO:0005802=IDA, GO:0005515=IPI, GO:0030132=IEA, GO:0030135=IDA, GO:0030136=IDA, GO:0005819=IDA, GO:0009653=TAS, GO:0006886=IEA, GO:0006898=IDA, GO:0007165=TAS, GO:0005905=IDA, GO:0007067=IDA, GO:0005198=IEA, GO:0046326=IMP, GO:0030130=IEA, GO:0004871=TAS, GO:0016192=IEA} anatomical structure morphogenesis, intracellular protein transport, mitosis, positive regulation of glucose import, receptor-mediated endocytosis, signal transduction, vesicle-mediated transport clathrin coat of coated pit, clathrin coat of trans-Golgi network vesicle, clathrin-coated vesicle, coated pit, coated vesicle, spindle, trans-Golgi network protein binding, signal transducer activity, structural molecule activity Human CLU BHF-UCL UniProtKB {GO:0005515=PMID:16113678, GO:0006629=PMID:2387851, GO:0008219=GO_REF:0000002, GO:0048471=PMID:20068069, GO:0005783=GO_REF:0000039, GO:0032436=PMID:20068069, GO:0001836=PMID:16113678, GO:0005634=GO_REF:0000039, GO:0005615=PMID:19996109, GO:0005829=GO_REF:0000039, GO:0005739=PMID:16113678, GO:0051787=PMID:19996109, GO:0051788=PMID:19996109, GO:0006956=PMID:1585460, GO:0051092=PMID:20068069, GO:0006958=GO_REF:0000037, GO:0031093=Reactome:REACT_21351, GO:0016887=PMID:11123922, GO:0031625=PMID:20068069, GO:0032463=PMID:16113678, GO:0043066=PMID:16113678, GO:0031966=GO_REF:0000039, GO:0043691=PMID:16682745, GO:0034366=PMID:16682745, GO:0050821=PMID:11123922, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_21351, GO:0009615=PMID:16548883, GO:2000060=PMID:20068069, GO:0061077=PMID:11123922, GO:0042583=GO_REF:0000039, GO:0007596=Reactome:REACT_604, GO:0045087=GO_REF:0000037, GO:0002576=Reactome:REACT_318} P10909 Clusterin protein 20100113 {GO:0005515=IPI, GO:0006629=NAS, GO:0008219=IEA, GO:0048471=IDA, GO:0005783=IEA, GO:0032436=IMP, GO:0001836=IC, GO:0005634=IEA, GO:0005615=IDA, GO:0005829=IEA, GO:0005739=IDA, GO:0051787=IPI, GO:0051788=IDA, GO:0006956=TAS, GO:0051092=IMP, GO:0006958=IEA, GO:0031093=TAS, GO:0016887=IDA, GO:0031625=IDA, GO:0032463=IMP, GO:0043066=IMP, GO:0031966=IEA, GO:0043691=TAS, GO:0034366=IDA, GO:0050821=IDA, GO:0030168=TAS, GO:0005576=TAS, GO:0009615=IEP, GO:2000060=IMP, GO:0061077=IDA, GO:0042583=IEA, GO:0007596=TAS, GO:0045087=IEA, GO:0002576=TAS} blood coagulation, cell death, chaperone-mediated protein folding, complement activation, complement activation, classical pathway, innate immune response, lipid metabolic process, negative regulation of apoptotic process, negative regulation of protein homooligomerization, platelet activation, platelet degranulation, positive regulation of NF-kappaB transcription factor activity, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process, protein stabilization, release of cytochrome c from mitochondria, response to misfolded protein, response to virus, reverse cholesterol transport chromaffin granule, cytosol, endoplasmic reticulum, extracellular region, extracellular space, mitochondrial membrane, mitochondrion, nucleus, perinuclear region of cytoplasm, platelet alpha granule lumen, spherical high-density lipoprotein particle ATPase activity, misfolded protein binding, protein binding, ubiquitin protein ligase binding Human CLUAP1 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0005929=GO_REF:0000039, GO:0030030=GO_REF:0000037, GO:0005634=GO_REF:0000039} Q96AJ1 Clusterin-associated protein 1 protein 20130415 {GO:0005515=IPI, GO:0005929=IEA, GO:0030030=IEA, GO:0005634=IEA} cell projection organization cilium, nucleus protein binding Human UniProtKB:P43364 CLYBL UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0006725=GO_REF:0000002, GO:0008815=GO_REF:0000002, GO:0016830=GO_REF:0000002, GO:0003824=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0009346=GO_REF:0000002} Q8N0X4 Citrate lyase subunit beta-like protein, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0006725=IEA, GO:0008815=IEA, GO:0016830=IEA, GO:0003824=IEA, GO:0046872=IEA, GO:0009346=IEA} cellular aromatic compound metabolic process citrate lyase complex, mitochondrion carbon-carbon lyase activity, catalytic activity, citrate (pro-3S)-lyase activity, metal ion binding Human UniProtKB-SubCell:SL-0173 CMA1 ENSEMBL UniProtKB {GO:0042277=GO_REF:0000019, GO:0004252=GO_REF:0000019, GO:0002003=Reactome:REACT_147707, GO:0050727=PMID:1919436, GO:0005576=GO_REF:0000019, GO:0045766=GO_REF:0000019, GO:0050720=PMID:1919436, GO:0005622=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0006508=GO_REF:0000019, GO:0008236=PMID:2071582, GO:0030901=GO_REF:0000019, GO:0071333=GO_REF:0000019, GO:0044267=Reactome:REACT_17015, GO:0006518=GO_REF:0000019} Q3SY37 Chymase protein 20130413 {GO:0042277=IEA, GO:0004252=IEA, GO:0002003=TAS, GO:0050727=IC, GO:0005576=IEA, GO:0045766=IEA, GO:0050720=IDA, GO:0005622=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0006508=IEA, GO:0008236=TAS, GO:0030901=IEA, GO:0071333=IEA, GO:0044267=TAS, GO:0006518=IEA} angiotensin maturation, cellular protein metabolic process, cellular response to glucose stimulus, extracellular matrix disassembly, extracellular matrix organization, interleukin-1 beta biosynthetic process, midbrain development, peptide metabolic process, positive regulation of angiogenesis, proteolysis, regulation of inflammatory response extracellular region, intracellular peptide binding, serine-type endopeptidase activity, serine-type peptidase activity Human Ensembl:ENSRNOP00000061330 CMAS UniPathway UniProtKB {GO:0006054=GO_REF:0000041, GO:0008781=GO_REF:0000003, GO:0005634=GO_REF:0000039, GO:0009103=GO_REF:0000002} Q8NFW8 N-acylneuraminate cytidylyltransferase protein 20130413 {GO:0006054=IEA, GO:0008781=IEA, GO:0005634=IEA, GO:0009103=IEA} N-acetylneuraminate metabolic process, lipopolysaccharide biosynthetic process nucleus N-acylneuraminate cytidylyltransferase activity Human UniPathway:UPA00628 CMBL UniProtKB UniProtKB {GO:0016787=GO_REF:0000037, GO:0005829=GO_REF:0000039} Q96DG6 Carboxymethylenebutenolidase homolog protein 20130413 {GO:0016787=IEA, GO:0005829=IEA} cytosol hydrolase activity Human UniProtKB-SubCell:SL-0091 CMIP UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0005634=GO_REF:0000039} Q8IY22 C-Maf-inducing protein protein 20130413 {GO:0005737=IEA, GO:0005543=IEA, GO:0005634=IEA} cytoplasm, nucleus phospholipid binding Human UniProtKB-SubCell:SL-0086 CMKLR1 GOC UniProtKB {GO:0005515=PMID:14530373, GO:0050848=PMID:14530373, GO:0070098=PMID:9425281, GO:0005886=PMID:14530373, GO:0004930=PMID:9603476, GO:0032088=PMID:15753205, GO:0006955=PMID:9425281, GO:0001501=PMID:9144535, GO:0006935=PMID:14530373, GO:0007186=PMID:14530373, GO:0005887=PMID:9425281, GO:0032695=GO_REF:0000024, GO:0004950=GO_REF:0000002, GO:0010759=PMID:19443732, GO:0004872=PMID:9144535, GO:0016021=PMID:9603476} Q99788 Chemokine-like receptor 1 protein 20130413 {GO:0005515=IPI, GO:0050848=IDA, GO:0070098=TAS, GO:0005886=IDA, GO:0004930=NAS, GO:0032088=IDA, GO:0006955=TAS, GO:0001501=TAS, GO:0006935=IDA, GO:0007186=IDA, GO:0005887=TAS, GO:0032695=ISS, GO:0004950=IEA, GO:0010759=IMP, GO:0004872=TAS, GO:0016021=NAS} G-protein coupled receptor signaling pathway, chemokine-mediated signaling pathway, chemotaxis, immune response, negative regulation of NF-kappaB transcription factor activity, negative regulation of interleukin-12 production, positive regulation of macrophage chemotaxis, regulation of calcium-mediated signaling, skeletal system development integral to membrane, integral to plasma membrane, plasma membrane G-protein coupled receptor activity, chemokine receptor activity, protein binding, receptor activity Human CMPK1 InterPro UniProtKB {GO:0006240=GO_REF:0000019, GO:0015949=Reactome:REACT_21330, GO:0018963=GO_REF:0000019, GO:0004127=GO_REF:0000003, GO:0004849=PMID:10462544, GO:0046705=GO_REF:0000019, GO:0006222=PMID:10462544, GO:0009220=PMID:10462544, GO:0055086=Reactome:REACT_1698, GO:0005634=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0006227=GO_REF:0000019, GO:0005524=GO_REF:0000002, GO:0006225=GO_REF:0000019, GO:0005829=Reactome:REACT_1618, GO:0019205=GO_REF:0000002, GO:0005737=PMID:10462544, GO:0006139=GO_REF:0000002, GO:0022602=GO_REF:0000019, GO:0033862=GO_REF:0000019} Q5T0D2 UMP-CMP kinase protein 20130413 {GO:0006240=IEA, GO:0015949=TAS, GO:0018963=IEA, GO:0004127=IEA, GO:0004849=TAS, GO:0046705=IEA, GO:0006222=TAS, GO:0009220=TAS, GO:0055086=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0006227=IEA, GO:0005524=IEA, GO:0006225=IEA, GO:0005829=TAS, GO:0019205=IEA, GO:0005737=TAS, GO:0006139=IEA, GO:0022602=IEA, GO:0033862=IEA} CDP biosynthetic process, UDP biosynthetic process, UMP biosynthetic process, dCDP biosynthetic process, dUDP biosynthetic process, nucleobase-containing compound metabolic process, nucleobase-containing small molecule interconversion, nucleobase-containing small molecule metabolic process, ovulation cycle process, phthalate metabolic process, pyrimidine ribonucleotide biosynthetic process, small molecule metabolic process cytoplasm, cytosol, nucleus ATP binding, UMP kinase activity, cytidylate kinase activity, nucleobase-containing compound kinase activity, uridine kinase activity Human InterPro:IPR000850 CMPK2 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0071222=GO_REF:0000019, GO:0004127=PMID:17999954, GO:0005730=GO_REF:0000052, GO:0033862=PMID:17999954, GO:0005634=GO_REF:0000052, GO:0006233=GO_REF:0000019, GO:0006227=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0004798=GO_REF:0000019} Q5EBM0 UMP-CMP kinase 2, mitochondrial protein 20111111 {GO:0005739=IDA, GO:0071222=IEA, GO:0004127=IDA, GO:0005730=IDA, GO:0033862=IDA, GO:0005634=IDA, GO:0006233=IEA, GO:0006227=IEA, GO:0005524=IEA, GO:0004798=IEA} cellular response to lipopolysaccharide, dTDP biosynthetic process, dUDP biosynthetic process mitochondrion, nucleolus, nucleus ATP binding, UMP kinase activity, cytidylate kinase activity, thymidylate kinase activity Human CMTM2 HPA UniProtKB {GO:0006935=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0016021=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037} Q8TAZ6 CKLF-like MARVEL transmembrane domain-containing protein 2 protein 20090616 {GO:0006935=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0016021=IEA, GO:0005615=IEA, GO:0005125=IEA} chemotaxis extracellular space, integral to membrane, nucleolus, nucleus cytokine activity NOT Human CMTM3 UniProtKB UniProtKB {GO:0006935=GO_REF:0000037, GO:0016020=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037} Q96MX0 CKLF-like MARVEL transmembrane domain-containing protein 3 protein 20130413 {GO:0006935=IEA, GO:0016020=IEA, GO:0016021=IEA, GO:0005615=IEA, GO:0005125=IEA} chemotaxis extracellular space, integral to membrane, membrane cytokine activity Human UniProtKB-KW:KW-0812 CMTM4 UniProtKB UniProtKB {GO:0006935=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037} Q8IZR5 CKLF-like MARVEL transmembrane domain-containing protein 4 protein 20130413 {GO:0006935=IEA, GO:0016021=IEA, GO:0005615=IEA, GO:0005125=IEA} chemotaxis extracellular space, integral to membrane cytokine activity Human UniProtKB-KW:KW-0812 CMTM6 UniProtKB UniProtKB {GO:0006935=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037} Q9NX76 CKLF-like MARVEL transmembrane domain-containing protein 6 protein 20130413 {GO:0006935=IEA, GO:0016021=IEA, GO:0005615=IEA, GO:0005125=IEA} chemotaxis extracellular space, integral to membrane cytokine activity Human UniProtKB-KW:KW-0812 CMTM7 UniProtKB UniProtKB {GO:0006935=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037} Q96FZ5 CKLF-like MARVEL transmembrane domain-containing protein 7 protein 20130413 {GO:0006935=IEA, GO:0016021=IEA, GO:0005615=IEA, GO:0005125=IEA} chemotaxis extracellular space, integral to membrane cytokine activity Human UniProtKB-KW:KW-0812 CMTM8 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0006935=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037} Q8IZV2 CKLF-like MARVEL transmembrane domain-containing protein 8 protein 20130413 {GO:0005737=IEA, GO:0006935=IEA, GO:0005634=IEA, GO:0016021=IEA, GO:0005615=IEA, GO:0005125=IEA} chemotaxis cytoplasm, extracellular space, integral to membrane, nucleus cytokine activity Human UniProtKB-SubCell:SL-0086 CMYA5 UniProtKB UniProtKB {GO:0048471=GO_REF:0000039, GO:0032513=GO_REF:0000019, GO:0043034=GO_REF:0000019, GO:0014733=GO_REF:0000019, GO:0031430=GO_REF:0000039, GO:0070885=GO_REF:0000019, GO:0042802=GO_REF:0000019} Q8N3K9 Cardiomyopathy-associated protein 5 protein 20130413 {GO:0048471=IEA, GO:0032513=IEA, GO:0043034=IEA, GO:0014733=IEA, GO:0031430=IEA, GO:0070885=IEA, GO:0042802=IEA} negative regulation of calcineurin-NFAT signaling cascade, negative regulation of protein phosphatase type 2B activity, regulation of skeletal muscle adaptation M band, costamere, perinuclear region of cytoplasm identical protein binding Human UniProtKB-SubCell:SL-0198 CNBP PINC UniProtKB {GO:0006695=PMID:2562787, GO:0008284=GO_REF:0000024, GO:0006355=PMID:2562787, GO:0003700=PMID:2562787, GO:0005783=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0005829=GO_REF:0000024, GO:0045944=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0045893=GO_REF:0000024} P62633 Cellular nucleic acid-binding protein protein 20061109 {GO:0006695=TAS, GO:0008284=ISS, GO:0006355=TAS, GO:0003700=TAS, GO:0005783=ISS, GO:0005634=ISS, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0005829=ISS, GO:0045944=ISS, GO:0008270=IEA, GO:0045893=ISS} cholesterol biosynthetic process, positive regulation of cell proliferation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytosol, endoplasmic reticulum, nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human CNDP1 UniProtKB UniProtKB {GO:0034701=GO_REF:0000002, GO:0004180=GO_REF:0000037, GO:0006508=GO_REF:0000037, GO:0005576=GO_REF:0000039, GO:0016805=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0008237=GO_REF:0000037} Q96KN2 Beta-Ala-His dipeptidase protein 20130413 {GO:0034701=IEA, GO:0004180=IEA, GO:0006508=IEA, GO:0005576=IEA, GO:0016805=IEA, GO:0046872=IEA, GO:0008237=IEA} proteolysis extracellular region carboxypeptidase activity, dipeptidase activity, metal ion binding, metallopeptidase activity, tripeptidase activity Human UniProtKB-SubCell:SL-0243 CNDP2 Reactome UniProtKB {GO:0006805=Reactome:REACT_13433, GO:0034701=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0016805=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_75845, GO:0034641=Reactome:REACT_13, GO:0000096=Reactome:REACT_115639, GO:0006750=Reactome:REACT_6960, GO:0006508=GO_REF:0000019, GO:0004180=Reactome:REACT_75845, GO:0008233=GO_REF:0000019, GO:0008237=GO_REF:0000037} Q96KP4 Cytosolic non-specific dipeptidase protein 20110503 {GO:0006805=TAS, GO:0034701=IEA, GO:0044281=TAS, GO:0016805=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0034641=TAS, GO:0000096=TAS, GO:0006750=TAS, GO:0006508=IEA, GO:0004180=TAS, GO:0008233=IEA, GO:0008237=IEA} cellular nitrogen compound metabolic process, glutathione biosynthetic process, proteolysis, small molecule metabolic process, sulfur amino acid metabolic process, xenobiotic metabolic process cytosol carboxypeptidase activity, dipeptidase activity, metal ion binding, metallopeptidase activity, peptidase activity, tripeptidase activity Human CNGA1 PINC UniProtKB {GO:0030553=GO_REF:0000037, GO:0005887=PMID:7479749, GO:0042622=GO_REF:0000019, GO:0006810=PMID:7479749, GO:0016021=GO_REF:0000038, GO:0007601=GO_REF:0000037, GO:0005216=GO_REF:0000002, GO:0050896=GO_REF:0000037} P29973 cGMP-gated cation channel alpha-1 protein 20030904 {GO:0030553=IEA, GO:0005887=TAS, GO:0042622=IEA, GO:0006810=TAS, GO:0016021=IEA, GO:0007601=IEA, GO:0005216=IEA, GO:0050896=IEA} response to stimulus, transport, visual perception integral to membrane, integral to plasma membrane, photoreceptor outer segment membrane cGMP binding, ion channel activity Human CNGA2 UniProtKB UniProtKB {GO:0007608=GO_REF:0000029, GO:0005516=GO_REF:0000037, GO:0030552=GO_REF:0000037, GO:0005222=GO_REF:0000029, GO:0050896=GO_REF:0000037, GO:0017071=GO_REF:0000029} Q16280 Cyclic nucleotide-gated olfactory channel protein 20021104 {GO:0007608=NAS, GO:0005516=IEA, GO:0030552=IEA, GO:0005222=NAS, GO:0050896=IEA, GO:0017071=NAS} response to stimulus, sensory perception of smell intracellular cyclic nucleotide activated cation channel complex cAMP binding, calmodulin binding, intracellular cAMP activated cation channel activity Human CNGA3 PINC UniProtKB {GO:0007165=PMID:9517456, GO:0046549=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0030553=GO_REF:0000037, GO:0005221=GO_REF:0000019, GO:0006810=PMID:9517456, GO:0016021=GO_REF:0000037, GO:0007601=GO_REF:0000037, GO:0005216=GO_REF:0000002, GO:0015276=PMID:9517456, GO:0001750=GO_REF:0000019} Q16281 Cyclic nucleotide-gated cation channel alpha-3 protein 20030904 {GO:0007165=TAS, GO:0046549=IEA, GO:0005886=IEA, GO:0030553=IEA, GO:0005221=IEA, GO:0006810=TAS, GO:0016021=IEA, GO:0007601=IEA, GO:0005216=IEA, GO:0015276=TAS, GO:0001750=IEA} retinal cone cell development, signal transduction, transport, visual perception integral to membrane, photoreceptor outer segment, plasma membrane cGMP binding, intracellular cyclic nucleotide activated cation channel activity, ion channel activity, ligand-gated ion channel activity Human CNGA4 ENSEMBL UniProtKB {GO:0007608=GO_REF:0000019, GO:0030552=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005216=GO_REF:0000002, GO:0050896=GO_REF:0000037} Q8IV77 Cyclic nucleotide-gated cation channel alpha-4 protein 20130413 {GO:0007608=IEA, GO:0030552=IEA, GO:0016021=IEA, GO:0005216=IEA, GO:0050896=IEA} response to stimulus, sensory perception of smell integral to membrane cAMP binding, ion channel activity Human Ensembl:ENSMUSP00000033187 CNGB1 PINC UniProtKB {GO:0043855=GO_REF:0000019, GO:0007608=GO_REF:0000019, GO:0030552=GO_REF:0000037, GO:0033365=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0005222=GO_REF:0000029, GO:0006810=PMID:7682292, GO:0045494=GO_REF:0000019, GO:0007602=GO_REF:0000019, GO:0007601=PMID:7682292, GO:0015276=PMID:7682292, GO:0017071=GO_REF:0000029} Q14028 Cyclic nucleotide-gated cation channel beta-1 protein 20030904 {GO:0043855=IEA, GO:0007608=IEA, GO:0030552=IEA, GO:0033365=IEA, GO:0016020=IEA, GO:0005222=NAS, GO:0006810=TAS, GO:0045494=IEA, GO:0007602=IEA, GO:0007601=TAS, GO:0015276=TAS, GO:0017071=NAS} photoreceptor cell maintenance, phototransduction, protein localization to organelle, sensory perception of smell, transport, visual perception intracellular cyclic nucleotide activated cation channel complex, membrane cAMP binding, cyclic nucleotide-gated ion channel activity, intracellular cAMP activated cation channel activity, ligand-gated ion channel activity Human CNGB3 PINC UniProtKB {GO:0005223=GO_REF:0000019, GO:0007165=PMID:10888875, GO:0030553=GO_REF:0000037, GO:0006810=PMID:10888875, GO:0016021=GO_REF:0000037, GO:0007601=GO_REF:0000037, GO:0001750=GO_REF:0000019} Q9NQW8 Cyclic nucleotide-gated cation channel beta-3 protein 20050308 {GO:0005223=IEA, GO:0007165=NAS, GO:0030553=IEA, GO:0006810=NAS, GO:0016021=IEA, GO:0007601=IEA, GO:0001750=IEA} signal transduction, transport, visual perception integral to membrane, photoreceptor outer segment cGMP binding, intracellular cGMP activated cation channel activity Human CNIH4 LIFEdb UniProtKB {GO:0035556=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0005783=GO_REF:0000054, GO:0016021=GO_REF:0000037} Q9P003 Protein cornichon homolog 4 protein 20100607 {GO:0035556=IEA, GO:0016020=IEA, GO:0005783=IDA, GO:0016021=IEA} intracellular signal transduction endoplasmic reticulum, integral to membrane, membrane Human CNKSR1 IntAct UniProtKB {GO:0005515=PMID:15670823, GO:0005543=GO_REF:0000002, GO:0005886=PMID:9814705, GO:0005911=PMID:9814705, GO:0016301=GO_REF:0000038, GO:0007265=PMID:14749388, GO:0007266=PMID:14749388, GO:0030674=PMID:14749388, GO:0005938=PMID:15075335, GO:0007169=PMID:9814705} Q969H4 Connector enhancer of kinase suppressor of ras 1 protein 20130415 {GO:0005515=IPI, GO:0005543=IEA, GO:0005886=TAS, GO:0005911=TAS, GO:0016301=IEA, GO:0007265=IPI, GO:0007266=IPI, GO:0030674=IDA, GO:0005938=IDA, GO:0007169=TAS} Ras protein signal transduction, Rho protein signal transduction, transmembrane receptor protein tyrosine kinase signaling pathway cell cortex, cell-cell junction, plasma membrane kinase activity, phospholipid binding, protein binding, protein binding, bridging Human UniProtKB:P61586 CNKSR2 UniProtKB UniProtKB {GO:0043005=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0045211=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0009966=GO_REF:0000002} Q8WXI2 Connector enhancer of kinase suppressor of ras 2 protein 20130413 {GO:0043005=IEA, GO:0005737=IEA, GO:0005543=IEA, GO:0045211=IEA, GO:0043025=IEA, GO:0009966=IEA} regulation of signal transduction cytoplasm, neuron projection, neuronal cell body, postsynaptic membrane phospholipid binding Human UniProtKB-SubCell:SL-0086 CNKSR3 UniProtKB UniProtKB {GO:0005737=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0010765=GO_REF:0000024, GO:0033137=GO_REF:0000024, GO:0070373=GO_REF:0000024, GO:0009966=GO_REF:0000002} Q6P9H4 Connector enhancer of kinase suppressor of ras 3 protein 20100528 {GO:0005737=IEA, GO:0016020=IEA, GO:0010765=ISS, GO:0033137=ISS, GO:0070373=ISS, GO:0009966=IEA} negative regulation of ERK1 and ERK2 cascade, negative regulation of peptidyl-serine phosphorylation, positive regulation of sodium ion transport, regulation of signal transduction cytoplasm, membrane Human UniProtKB:Q8BMA3 CNN1 MGI UniProtKB {GO:0005516=GO_REF:0000037, GO:0031032=GO_REF:0000002, GO:0003779=GO_REF:0000019, GO:0006940=PMID:14550641, GO:0005856=PMID:8616889} P51911 Calponin-1 protein 20100316 {GO:0005516=IEA, GO:0031032=IEA, GO:0003779=IEA, GO:0006940=TAS, GO:0005856=IDA} actomyosin structure organization, regulation of smooth muscle contraction cytoskeleton actin binding, calmodulin binding Human CNN2 PINC UniProtKB {GO:0030097=GO_REF:0000019, GO:0005516=GO_REF:0000037, GO:0030336=GO_REF:0000019, GO:0001725=PMID:16236705, GO:0031032=GO_REF:0000002, GO:0003779=GO_REF:0000037, GO:0010628=GO_REF:0000019, GO:0050765=GO_REF:0000019, GO:0032970=PMID:16236705, GO:0005911=PMID:8889829, GO:0042127=GO_REF:0000019, GO:0007010=PMID:8889829, GO:0042060=GO_REF:0000019, GO:0071260=PMID:16236705, GO:0005856=PMID:8889829} Q99439 Calponin-2 protein 20030904 {GO:0030097=IEA, GO:0005516=IEA, GO:0030336=IEA, GO:0001725=IDA, GO:0031032=IEA, GO:0003779=IEA, GO:0010628=IEA, GO:0050765=IEA, GO:0032970=IDA, GO:0005911=TAS, GO:0042127=IEA, GO:0007010=TAS, GO:0042060=IEA, GO:0071260=IDA, GO:0005856=TAS} actomyosin structure organization, cellular response to mechanical stimulus, cytoskeleton organization, hemopoiesis, negative regulation of cell migration, negative regulation of phagocytosis, positive regulation of gene expression, regulation of actin filament-based process, regulation of cell proliferation, wound healing cell-cell junction, cytoskeleton, stress fiber actin binding, calmodulin binding Human CNN3 UniProtKB UniProtKB {GO:0006939=GO_REF:0000029, GO:0008017=GO_REF:0000019, GO:0030172=GO_REF:0000029, GO:0005516=GO_REF:0000029, GO:0043025=GO_REF:0000019, GO:0014069=GO_REF:0000019, GO:0031032=GO_REF:0000002, GO:0032780=GO_REF:0000019, GO:0003779=GO_REF:0000029, GO:0005575=GO_REF:0000015, GO:0005523=GO_REF:0000029} Q15417 Calponin-3 protein 20061026 {GO:0006939=NAS, GO:0008017=IEA, GO:0030172=NAS, GO:0005516=NAS, GO:0043025=IEA, GO:0014069=IEA, GO:0031032=IEA, GO:0032780=IEA, GO:0003779=NAS, GO:0005575=ND, GO:0005523=NAS} actomyosin structure organization, negative regulation of ATPase activity, smooth muscle contraction cellular_component, neuronal cell body, postsynaptic density actin binding, calmodulin binding, microtubule binding, tropomyosin binding, troponin C binding Human CNNM2 MGI UniProtKB {GO:0016323=PMID:21397062, GO:0015693=GO_REF:0000019, GO:0010960=PMID:21397062, GO:0016021=GO_REF:0000037} Q9H8M5 Metal transporter CNNM2 protein 20120328 {GO:0016323=IMP, GO:0015693=IEA, GO:0010960=IMP, GO:0016021=IEA} magnesium ion homeostasis, magnesium ion transport basolateral plasma membrane, integral to membrane Human CNNM3 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0006811=GO_REF:0000037} Q8NE01 Metal transporter CNNM3 protein 20130415 {GO:0005515=IPI, GO:0005886=IEA, GO:0016021=IEA, GO:0006811=IEA} ion transport integral to membrane, plasma membrane protein binding Human UniProtKB:Q99750 CNNM4 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0031214=GO_REF:0000037, GO:0007601=GO_REF:0000037, GO:0050896=GO_REF:0000037, GO:0006811=GO_REF:0000037} Q6P4Q7 Metal transporter CNNM4 protein 20130413 {GO:0005886=IEA, GO:0016021=IEA, GO:0031214=IEA, GO:0007601=IEA, GO:0050896=IEA, GO:0006811=IEA} biomineral tissue development, ion transport, response to stimulus, visual perception integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 CNOT1 IntAct UniProtKB {GO:0005515=PMID:23232451, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0030331=PMID:16778766, GO:0060213=PMID:21278420, GO:0000122=PMID:16778766, GO:0042974=PMID:16778766, GO:0006351=GO_REF:0000037, GO:0030014=PMID:19558367, GO:2000036=PMID:22367759, GO:0005829=Reactome:REACT_20651, GO:0004535=PMID:21976065, GO:0010606=PMID:21976065, GO:1900153=PMID:21278420, GO:0048387=PMID:16778766, GO:0000932=GO_REF:0000024, GO:0033147=PMID:16778766, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639} A5YKK6 CCR4-NOT transcription complex subunit 1 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0030331=IDA, GO:0060213=IMP, GO:0000122=IDA, GO:0042974=IDA, GO:0006351=IEA, GO:0030014=IDA, GO:2000036=IMP, GO:0005829=TAS, GO:0004535=IDA, GO:0010606=IDA, GO:1900153=IMP, GO:0048387=IDA, GO:0000932=ISS, GO:0033147=IDA, GO:0000289=TAS, GO:0000288=TAS} RNA metabolic process, gene expression, mRNA metabolic process, negative regulation of intracellular estrogen receptor signaling pathway, negative regulation of retinoic acid receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA poly(A) tail shortening, positive regulation of cytoplasmic mRNA processing body assembly, positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, positive regulation of nuclear-transcribed mRNA poly(A) tail shortening, regulation of stem cell maintenance, transcription, DNA-dependent CCR4-NOT complex, cytoplasmic mRNA processing body, cytosol estrogen receptor binding, poly(A)-specific ribonuclease activity, protein binding, retinoic acid receptor binding Human UniProtKB:Q9UKZ1 CNOT10 IntAct UniProtKB {GO:0005515=PMID:23232451, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0000289=Reactome:REACT_20514, GO:0030014=PMID:19558367, GO:0005829=Reactome:REACT_20651, GO:0000288=Reactome:REACT_20639} Q9H9A5 CCR4-NOT transcription complex subunit 10 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0000289=TAS, GO:0030014=IDA, GO:0005829=TAS, GO:0000288=TAS} RNA metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA poly(A) tail shortening CCR4-NOT complex, cytosol protein binding Human UniProtKB:Q9UKZ1 CNOT2 IntAct UniProtKB {GO:0005515=PMID:21981923, GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000002, GO:0001104=PMID:10637334, GO:0016070=Reactome:REACT_21257, GO:0006357=PMID:10637334, GO:0016071=Reactome:REACT_20605, GO:0005634=PMID:10637334, GO:0001226=PMID:16712523, GO:0000122=PMID:14707134, GO:0030014=PMID:19558367, GO:2000036=PMID:22367759, GO:0005829=Reactome:REACT_20651, GO:0004535=PMID:21299754, GO:0005737=PMID:21299754, GO:0010606=PMID:21299754, GO:0033147=PMID:16778766, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639} Q9NZN8 CCR4-NOT transcription complex subunit 2 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0006355=IEA, GO:0001104=TAS, GO:0016070=TAS, GO:0006357=NAS, GO:0016071=TAS, GO:0005634=NAS, GO:0001226=IDA, GO:0000122=IDA, GO:0030014=IDA, GO:2000036=IMP, GO:0005829=TAS, GO:0004535=IMP, GO:0005737=IDA, GO:0010606=IMP, GO:0033147=IMP, GO:0000289=TAS, GO:0000288=TAS} RNA metabolic process, gene expression, mRNA metabolic process, negative regulation of intracellular estrogen receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA poly(A) tail shortening, positive regulation of cytoplasmic mRNA processing body assembly, regulation of stem cell maintenance, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent CCR4-NOT complex, cytoplasm, cytosol, nucleus RNA polymerase II transcription cofactor activity, RNA polymerase II transcription corepressor binding, poly(A)-specific ribonuclease activity, protein binding Human UniProtKB:Q9HCJ0 CNOT3 HPA UniProtKB {GO:0005515=PMID:10637334, GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000037, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037, GO:0030014=PMID:19558367, GO:2000036=PMID:22367759, GO:0005829=Reactome:REACT_20651, GO:0005737=GO_REF:0000052, GO:0000932=GO_REF:0000024, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639} O75175 CCR4-NOT transcription complex subunit 3 protein 20080205 {GO:0005515=IPI, GO:0010467=TAS, GO:0006355=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0005634=IEA, GO:0006351=IEA, GO:0030014=IDA, GO:2000036=IMP, GO:0005829=TAS, GO:0005737=IDA, GO:0000932=ISS, GO:0000289=TAS, GO:0000288=TAS} RNA metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA poly(A) tail shortening, regulation of stem cell maintenance, regulation of transcription, DNA-dependent, transcription, DNA-dependent CCR4-NOT complex, cytoplasm, cytoplasmic mRNA processing body, cytosol, nucleus protein binding Human CNOT4 Reactome UniProtKB {GO:0005515=PMID:15001359, GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000037, GO:0004842=PMID:15001359, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037, GO:0030014=PMID:19558367, GO:0051865=PMID:15001359, GO:0005829=Reactome:REACT_20651, GO:0000166=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639} O95628 CCR4-NOT transcription complex subunit 4 protein 20090723 {GO:0005515=IPI, GO:0010467=TAS, GO:0006355=IEA, GO:0004842=IDA, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=IEA, GO:0005634=IEA, GO:0006351=IEA, GO:0030014=IDA, GO:0051865=IDA, GO:0005829=TAS, GO:0000166=IEA, GO:0008270=IEA, GO:0000289=TAS, GO:0000288=TAS} RNA metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA poly(A) tail shortening, protein autoubiquitination, regulation of transcription, DNA-dependent, transcription, DNA-dependent CCR4-NOT complex, cytosol, nucleus RNA binding, nucleotide binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human CNOT6 IntAct UniProtKB {GO:0005515=PMID:21981923, GO:0010467=Reactome:REACT_71, GO:2000327=PMID:18180299, GO:0006355=GO_REF:0000037, GO:0008284=PMID:21233283, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=GO_REF:0000037, GO:0004532=PMID:11889047, GO:0043928=PMID:20065043, GO:0005634=GO_REF:0000039, GO:0070966=PMID:15314026, GO:0046872=GO_REF:0000037, GO:0030014=PMID:19558367, GO:0006351=GO_REF:0000037, GO:0005829=Reactome:REACT_20651, GO:0004535=Reactome:REACT_20651, GO:0010606=PMID:21233283, GO:0035195=PMID:20065043, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639} Q9ULM6 CCR4-NOT transcription complex subunit 6 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:2000327=IDA, GO:0006355=IEA, GO:0008284=IMP, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=IEA, GO:0004532=IDA, GO:0043928=IDA, GO:0005634=IEA, GO:0070966=IMP, GO:0046872=IEA, GO:0030014=IDA, GO:0006351=IEA, GO:0005829=TAS, GO:0004535=TAS, GO:0010606=IMP, GO:0035195=TAS, GO:0000289=TAS, GO:0000288=TAS} RNA metabolic process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, gene silencing by miRNA, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA catabolic process, no-go decay, nuclear-transcribed mRNA poly(A) tail shortening, positive regulation of cell proliferation, positive regulation of cytoplasmic mRNA processing body assembly, positive regulation of ligand-dependent nuclear receptor transcription coactivator activity, regulation of transcription, DNA-dependent, transcription, DNA-dependent CCR4-NOT complex, cytosol, nucleus RNA binding, exoribonuclease activity, metal ion binding, poly(A)-specific ribonuclease activity, protein binding Human UniProtKB:Q9HCJ0 CNOT6L Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0008284=PMID:21233283, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0005634=PMID:21233283, GO:0046872=GO_REF:0000037, GO:0030014=PMID:19558367, GO:0005829=Reactome:REACT_20651, GO:0061157=GO_REF:0000019, GO:0004535=Reactome:REACT_20651, GO:0005737=PMID:21233283, GO:0010606=PMID:21233283, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639} Q96LI5 CCR4-NOT transcription complex subunit 6-like protein 20130301 {GO:0010467=TAS, GO:0008284=IMP, GO:0016070=TAS, GO:0016071=TAS, GO:0005634=IDA, GO:0046872=IEA, GO:0030014=IDA, GO:0005829=TAS, GO:0061157=IEA, GO:0004535=TAS, GO:0005737=IDA, GO:0010606=IMP, GO:0000289=TAS, GO:0000288=TAS} RNA metabolic process, gene expression, mRNA destabilization, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA poly(A) tail shortening, positive regulation of cell proliferation, positive regulation of cytoplasmic mRNA processing body assembly CCR4-NOT complex, cytoplasm, cytosol, nucleus metal ion binding, poly(A)-specific ribonuclease activity Human CNOT7 IntAct UniProtKB {GO:0005515=PMID:22977175, GO:0010467=Reactome:REACT_71, GO:0008284=PMID:19605561, GO:0008285=PMID:19276069, GO:0003700=PMID:9820826, GO:0000290=GO_REF:0000019, GO:0004532=PMID:19276069, GO:0005634=PMID:9820826, GO:0031047=GO_REF:0000024, GO:0030014=PMID:19558367, GO:0005829=Reactome:REACT_20651, GO:0000932=GO_REF:0000024, GO:0045944=GO_REF:0000019, GO:0004871=PMID:9820826, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639, GO:0033962=GO_REF:0000019, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0005975=PMID:9820826, GO:0060213=PMID:21278420, GO:0043928=PMID:20065043, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0004535=PMID:19276069, GO:0007165=PMID:9820826, GO:0000175=PMID:15769875, GO:1900153=PMID:21278420, GO:0035195=PMID:20065043} Q9UIV1 CCR4-NOT transcription complex subunit 7 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0008284=IMP, GO:0008285=IDA, GO:0003700=TAS, GO:0000290=IEA, GO:0004532=IDA, GO:0005634=IDA, GO:0031047=ISS, GO:0030014=IDA, GO:0005829=TAS, GO:0000932=ISS, GO:0045944=IEA, GO:0004871=TAS, GO:0000289=TAS, GO:0000288=TAS, GO:0033962=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0005975=TAS, GO:0060213=IMP, GO:0043928=IDA, GO:0003676=IEA, GO:0006351=IEA, GO:0004535=IDA, GO:0007165=TAS, GO:0000175=IDA, GO:1900153=IMP, GO:0035195=TAS} RNA metabolic process, carbohydrate metabolic process, cytoplasmic mRNA processing body assembly, deadenylation-dependent decapping of nuclear-transcribed mRNA, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, gene silencing by RNA, gene silencing by miRNA, mRNA metabolic process, negative regulation of cell proliferation, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA poly(A) tail shortening, positive regulation of cell proliferation, positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, positive regulation of nuclear-transcribed mRNA poly(A) tail shortening, positive regulation of transcription from RNA polymerase II promoter, signal transduction, transcription, DNA-dependent CCR4-NOT complex, cytoplasmic mRNA processing body, cytosol, nucleus 3'-5'-exoribonuclease activity, exoribonuclease activity, nucleic acid binding, poly(A)-specific ribonuclease activity, protein binding, sequence-specific DNA binding transcription factor activity, signal transducer activity Human UniProtKB:A5YKK6 CNOT8 IntAct UniProtKB {GO:0005515=PMID:22977175, GO:0010467=Reactome:REACT_71, GO:0006355=PMID:10036195, GO:0008284=PMID:19605561, GO:0003700=PMID:10036195, GO:0008285=PMID:9820826, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0043928=PMID:20065043, GO:0005634=PMID:10036195, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0030014=PMID:19558367, GO:0005829=Reactome:REACT_20651, GO:0005622=GO_REF:0000054, GO:0004535=PMID:15769875, GO:0000175=PMID:15769875, GO:0035195=PMID:20065043, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639} Q9UFF9 CCR4-NOT transcription complex subunit 8 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0006355=NAS, GO:0008284=IMP, GO:0003700=NAS, GO:0008285=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0043928=IDA, GO:0005634=NAS, GO:0003676=IEA, GO:0006351=IEA, GO:0030014=IDA, GO:0005829=TAS, GO:0005622=IDA, GO:0004535=IDA, GO:0000175=IDA, GO:0035195=TAS, GO:0000289=TAS, GO:0000288=TAS} RNA metabolic process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, gene silencing by miRNA, mRNA metabolic process, negative regulation of cell proliferation, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA poly(A) tail shortening, positive regulation of cell proliferation, regulation of transcription, DNA-dependent, transcription, DNA-dependent CCR4-NOT complex, cytosol, intracellular, nucleus 3'-5'-exoribonuclease activity, nucleic acid binding, poly(A)-specific ribonuclease activity, protein binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:A5YKK6 CNP BHF-UCL UniProtKB {GO:0008344=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0003723=GO_REF:0000037, GO:0005743=GO_REF:0000019, GO:0007268=PMID:1322358, GO:0005741=GO_REF:0000019, GO:0007409=GO_REF:0000019, GO:0005615=PMID:12379507, GO:0031143=GO_REF:0000019, GO:0035749=GO_REF:0000019, GO:0030551=GO_REF:0000019, GO:0005737=PMID:12379507, GO:0032496=GO_REF:0000019, GO:0035748=GO_REF:0000019, GO:0046902=GO_REF:0000019, GO:0042470=GO_REF:0000039, GO:0016070=GO_REF:0000002, GO:0009214=GO_REF:0000002, GO:0004113=GO_REF:0000003, GO:0007568=GO_REF:0000019, GO:0009636=GO_REF:0000019, GO:0000226=GO_REF:0000019, GO:0005902=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0030900=GO_REF:0000019} P09543 2',3'-cyclic-nucleotide 3'-phosphodiesterase protein 20080215 {GO:0008344=IEA, GO:0048471=IEA, GO:0005886=IEA, GO:0003723=IEA, GO:0005743=IEA, GO:0007268=TAS, GO:0005741=IEA, GO:0007409=IEA, GO:0005615=IDA, GO:0031143=IEA, GO:0035749=IEA, GO:0030551=IEA, GO:0005737=IDA, GO:0032496=IEA, GO:0035748=IEA, GO:0046902=IEA, GO:0042470=IEA, GO:0016070=IEA, GO:0009214=IEA, GO:0004113=IEA, GO:0007568=IEA, GO:0009636=IEA, GO:0000226=IEA, GO:0005902=IEA, GO:0016020=IEA, GO:0030900=IEA} RNA metabolic process, adult locomotory behavior, aging, axonogenesis, cyclic nucleotide catabolic process, forebrain development, microtubule cytoskeleton organization, regulation of mitochondrial membrane permeability, response to lipopolysaccharide, response to toxic substance, synaptic transmission cytoplasm, extracellular space, melanosome, membrane, microvillus, mitochondrial inner membrane, mitochondrial outer membrane, myelin sheath abaxonal region, myelin sheath adaxonal region, perinuclear region of cytoplasm, plasma membrane, pseudopodium 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity, RNA binding, cyclic nucleotide binding Human CNPPD1 UniProtKB UniProtKB {GO:0019901=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0000079=GO_REF:0000002} Q9BV87 Protein CNPPD1 protein 20130413 {GO:0019901=IEA, GO:0016021=IEA, GO:0000079=IEA} regulation of cyclin-dependent protein serine/threonine kinase activity integral to membrane protein kinase binding Human UniProtKB-KW:KW-0812 CNPY2 BHF-UCL UniProtKB {GO:0005515=PMID:12826659, GO:0005887=PMID:10072769, GO:0005783=GO_REF:0000039, GO:0010629=PMID:22378787, GO:0010988=PMID:22378787, GO:0045716=PMID:22378787} Q9Y2B0 Protein canopy homolog 2 protein 20120601 {GO:0005515=IPI, GO:0005887=TAS, GO:0005783=IEA, GO:0010629=ISS, GO:0010988=ISS, GO:0045716=ISS} negative regulation of gene expression, positive regulation of low-density lipoprotein particle receptor biosynthetic process, regulation of low-density lipoprotein particle clearance endoplasmic reticulum, integral to plasma membrane protein binding Human UniProtKB:Q9QXT0 CNPY4 UniProtKB UniProtKB {GO:0005102=GO_REF:0000019, GO:0005576=GO_REF:0000039} Q8N129 Protein canopy homolog 4 protein 20130413 {GO:0005102=IEA, GO:0005576=IEA} extracellular region receptor binding Human UniProtKB-SubCell:SL-0243 CNR1 Reactome UniProtKB {GO:0002866=GO_REF:0000019, GO:0005886=Reactome:REACT_22289, GO:0060405=GO_REF:0000019, GO:0031999=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0045776=GO_REF:0000019, GO:0042220=GO_REF:0000019, GO:0045777=GO_REF:0000019, GO:0033004=GO_REF:0000019, GO:0045759=GO_REF:0000019, GO:0004949=PMID:18761332, GO:0031622=GO_REF:0000019, GO:0008144=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0007610=PMID:1718258, GO:0007613=GO_REF:0000019, GO:0051966=GO_REF:0000019, GO:0060259=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0007584=GO_REF:0000019, GO:0060135=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0006950=GO_REF:0000019, GO:0043278=GO_REF:0000019, GO:0019233=GO_REF:0000019, GO:0051001=GO_REF:0000019, GO:0050796=GO_REF:0000019, GO:0007187=PMID:1718258, GO:0005887=PMID:1718258, GO:0032228=GO_REF:0000019, GO:0010976=GO_REF:0000019, GO:0007188=PMID:18761332, GO:0016021=GO_REF:0000002, GO:0033602=GO_REF:0000019, GO:0035094=GO_REF:0000019} P21554 Cannabinoid receptor 1 protein 20090430 {GO:0002866=IEA, GO:0005886=TAS, GO:0060405=IEA, GO:0031999=IEA, GO:0045471=IEA, GO:0007283=IEA, GO:0045776=IEA, GO:0042220=IEA, GO:0045777=IEA, GO:0033004=IEA, GO:0045759=IEA, GO:0004949=IDA, GO:0031622=IEA, GO:0008144=IEA, GO:0032496=IEA, GO:0007610=TAS, GO:0007613=IEA, GO:0051966=IEA, GO:0060259=IEA, GO:0043065=IEA, GO:0007584=IEA, GO:0060135=IEA, GO:0007568=IEA, GO:0006950=IEA, GO:0043278=IEA, GO:0019233=IEA, GO:0051001=IEA, GO:0050796=IEA, GO:0007187=TAS, GO:0005887=TAS, GO:0032228=IEA, GO:0010976=IEA, GO:0007188=IDA, GO:0016021=IEA, GO:0033602=IEA, GO:0035094=IEA} G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, aging, behavior, maternal process involved in female pregnancy, memory, negative regulation of action potential, negative regulation of blood pressure, negative regulation of dopamine secretion, negative regulation of fatty acid beta-oxidation, negative regulation of mast cell activation, negative regulation of nitric-oxide synthase activity, positive regulation of acute inflammatory response to antigenic stimulus, positive regulation of apoptotic process, positive regulation of blood pressure, positive regulation of fever generation, positive regulation of neuron projection development, regulation of feeding behavior, regulation of insulin secretion, regulation of penile erection, regulation of synaptic transmission, GABAergic, regulation of synaptic transmission, glutamatergic, response to cocaine, response to ethanol, response to lipopolysaccharide, response to morphine, response to nicotine, response to nutrient, response to stress, sensory perception of pain, spermatogenesis integral to membrane, integral to plasma membrane, plasma membrane cannabinoid receptor activity, drug binding Human CNR2 Reactome UniProtKB {GO:0005886=Reactome:REACT_22289, GO:0033004=GO_REF:0000019, GO:0045759=GO_REF:0000019, GO:0019233=GO_REF:0000019, GO:0030425=GO_REF:0000039, GO:0004949=GO_REF:0000019, GO:0031234=GO_REF:0000019, GO:0006955=PMID:7556170, GO:0001975=GO_REF:0000019, GO:0006954=GO_REF:0000037, GO:0051001=GO_REF:0000019, GO:0007187=PMID:8679694, GO:0005887=PMID:8679694, GO:0050728=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0007610=GO_REF:0000019, GO:0032229=GO_REF:0000019, GO:0043204=GO_REF:0000039} P34972 Cannabinoid receptor 2 protein 20090430 {GO:0005886=TAS, GO:0033004=IEA, GO:0045759=IEA, GO:0019233=IEA, GO:0030425=IEA, GO:0004949=IEA, GO:0031234=IEA, GO:0006955=TAS, GO:0001975=IEA, GO:0006954=IEA, GO:0051001=IEA, GO:0007187=TAS, GO:0005887=TAS, GO:0050728=IEA, GO:0032496=IEA, GO:0007610=IEA, GO:0032229=IEA, GO:0043204=IEA} G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, behavior, immune response, inflammatory response, negative regulation of action potential, negative regulation of inflammatory response, negative regulation of mast cell activation, negative regulation of nitric-oxide synthase activity, negative regulation of synaptic transmission, GABAergic, response to amphetamine, response to lipopolysaccharide, sensory perception of pain dendrite, extrinsic to internal side of plasma membrane, integral to plasma membrane, perikaryon, plasma membrane cannabinoid receptor activity Human CNRIP1 null null {} null null null null {} null null null CNST IntAct UniProtKB {GO:0005515=PMID:22321011, GO:0030133=PMID:19864490, GO:0005802=PMID:19864490, GO:0043234=GO_REF:0000054, GO:0005794=GO_REF:0000039, GO:0005886=PMID:19864490, GO:0019902=PMID:19389623, GO:0010923=PMID:19389623, GO:0042998=PMID:19864490, GO:0016021=GO_REF:0000037, GO:0071253=GO_REF:0000024} Q6PJW8 Consortin protein 20130415 {GO:0005515=IPI, GO:0030133=IDA, GO:0005802=IDA, GO:0043234=IDA, GO:0005794=IEA, GO:0005886=IDA, GO:0019902=IDA, GO:0010923=IDA, GO:0042998=IMP, GO:0016021=IEA, GO:0071253=ISS} negative regulation of phosphatase activity, positive regulation of Golgi to plasma membrane protein transport Golgi apparatus, integral to membrane, plasma membrane, protein complex, trans-Golgi network, transport vesicle connexin binding, phosphatase binding, protein binding Human UniProtKB:P62136 CNTF HPA UniProtKB {GO:0005138=PMID:12643274, GO:0046533=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0042517=PMID:12643274, GO:0070120=PMID:12643274, GO:0005615=PMID:12643274, GO:0043231=GO_REF:0000052, GO:0097058=PMID:10966616, GO:0005127=PMID:1714745, GO:0048644=GO_REF:0000019, GO:0007165=PMID:1840538, GO:0043524=PMID:10966616, GO:0005737=GO_REF:0000039, GO:0048666=GO_REF:0000019, GO:0040007=GO_REF:0000002, GO:0008083=PMID:12643274, GO:0046668=GO_REF:0000019} P26441 Ciliary neurotrophic factor protein 20101115 {GO:0005138=IPI, GO:0046533=IEA, GO:0008284=IEA, GO:0042517=IDA, GO:0070120=IDA, GO:0005615=IC, GO:0043231=IDA, GO:0097058=IDA, GO:0005127=TAS, GO:0048644=IEA, GO:0007165=NAS, GO:0043524=IDA, GO:0005737=IEA, GO:0048666=IEA, GO:0040007=IEA, GO:0008083=IDA, GO:0046668=IEA} ciliary neurotrophic factor-mediated signaling pathway, growth, muscle organ morphogenesis, negative regulation of neuron apoptotic process, negative regulation of photoreceptor cell differentiation, neuron development, positive regulation of cell proliferation, positive regulation of tyrosine phosphorylation of Stat3 protein, regulation of retinal cell programmed cell death, signal transduction CRLF-CLCF1 complex, cytoplasm, extracellular space, intracellular membrane-bounded organelle ciliary neurotrophic factor receptor binding, growth factor activity, interleukin-6 receptor binding Human CNTFR ENSEMBL UniProtKB {GO:0008284=GO_REF:0000019, GO:0003360=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0097059=PMID:11285233, GO:0005102=PMID:12707266, GO:0031225=GO_REF:0000037, GO:0070120=PMID:12643274, GO:0007399=PMID:7585948, GO:0007165=PMID:1648265, GO:0043524=GO_REF:0000019, GO:0001967=GO_REF:0000019, GO:0019955=PMID:15272019, GO:0016020=GO_REF:0000002, GO:0060538=GO_REF:0000019, GO:0007548=GO_REF:0000019, GO:0004897=GO_REF:0000019, GO:0019898=PMID:1648265} Q5T8H6 Ciliary neurotrophic factor receptor subunit alpha protein 20130413 {GO:0008284=IEA, GO:0003360=IEA, GO:0005886=IEA, GO:0097059=IDA, GO:0005102=IPI, GO:0031225=IEA, GO:0070120=IDA, GO:0007399=TAS, GO:0007165=NAS, GO:0043524=IEA, GO:0001967=IEA, GO:0019955=IPI, GO:0016020=IEA, GO:0060538=IEA, GO:0007548=IEA, GO:0004897=IEA, GO:0019898=TAS} brainstem development, ciliary neurotrophic factor-mediated signaling pathway, negative regulation of neuron apoptotic process, nervous system development, positive regulation of cell proliferation, sex differentiation, signal transduction, skeletal muscle organ development, suckling behavior CNTFR-CLCF1 complex, anchored to membrane, extrinsic to membrane, membrane, plasma membrane ciliary neurotrophic factor receptor activity, cytokine binding, receptor binding Human Ensembl:ENSMUSP00000100026 CNTLN HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005813=GO_REF:0000052, GO:0016020=GO_REF:0000002, GO:0005814=GO_REF:0000039, GO:0000155=GO_REF:0000002} Q9NXG0 Centlein protein 20110516 {GO:0005739=IDA, GO:0005813=IDA, GO:0016020=IEA, GO:0005814=IEA, GO:0000155=IEA} centriole, centrosome, membrane, mitochondrion phosphorelay sensor kinase activity Human CNTN1 Reactome UniProtKB {GO:0005886=GO_REF:0000039, GO:0021549=GO_REF:0000019, GO:0031225=GO_REF:0000037, GO:0031175=GO_REF:0000019, GO:0010628=GO_REF:0000019, GO:0001948=GO_REF:0000019, GO:0016020=PMID:7959734, GO:0007219=Reactome:REACT_118859, GO:0010765=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0010976=GO_REF:0000019, GO:0030246=GO_REF:0000019, GO:0007155=GO_REF:0000037} Q12860 Contactin-1 protein 20100322 {GO:0005886=IEA, GO:0021549=IEA, GO:0031225=IEA, GO:0031175=IEA, GO:0010628=IEA, GO:0001948=IEA, GO:0016020=TAS, GO:0007219=TAS, GO:0010765=IEA, GO:0007411=TAS, GO:0010976=IEA, GO:0030246=IEA, GO:0007155=IEA} Notch signaling pathway, axon guidance, cell adhesion, cerebellum development, neuron projection development, positive regulation of gene expression, positive regulation of neuron projection development, positive regulation of sodium ion transport anchored to membrane, membrane, plasma membrane carbohydrate binding, glycoprotein binding Human CNTN2 BHF-UCL UniProtKB {GO:0005886=GO_REF:0000024, GO:0022010=GO_REF:0000019, GO:0045202=GO_REF:0000024, GO:0031225=GO_REF:0000037, GO:0043621=GO_REF:0000019, GO:0042802=PMID:12963709, GO:0031623=GO_REF:0000019, GO:0007413=GO_REF:0000019, GO:0001948=GO_REF:0000019, GO:0048168=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0043209=GO_REF:0000024, GO:0008076=GO_REF:0000019, GO:0007628=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0060168=GO_REF:0000019, GO:0007612=GO_REF:0000019, GO:0007155=GO_REF:0000037, GO:0009986=GO_REF:0000019, GO:0044224=GO_REF:0000024, GO:0031133=GO_REF:0000019, GO:0000226=GO_REF:0000019, GO:0021853=GO_REF:0000019, GO:0048710=GO_REF:0000019, GO:0033268=GO_REF:0000024, GO:0010954=GO_REF:0000019, GO:0045665=GO_REF:0000019, GO:0045163=GO_REF:0000024, GO:0005887=PMID:8425542, GO:0030246=GO_REF:0000019, GO:0034613=GO_REF:0000024, GO:0001764=GO_REF:0000019, GO:0071206=GO_REF:0000019} Q02246 Contactin-2 protein 20091117 {GO:0005886=ISS, GO:0022010=IEA, GO:0045202=ISS, GO:0031225=IEA, GO:0043621=IEA, GO:0042802=TAS, GO:0031623=IEA, GO:0007413=IEA, GO:0001948=IEA, GO:0048168=IEA, GO:0007411=TAS, GO:0043209=ISS, GO:0008076=IEA, GO:0007628=IEA, GO:0043025=IEA, GO:0060168=IEA, GO:0007612=IEA, GO:0007155=IEA, GO:0009986=IEA, GO:0044224=ISS, GO:0031133=IEA, GO:0000226=IEA, GO:0021853=IEA, GO:0048710=IEA, GO:0033268=ISS, GO:0010954=IEA, GO:0045665=IEA, GO:0045163=ISS, GO:0005887=TAS, GO:0030246=IEA, GO:0034613=ISS, GO:0001764=IEA, GO:0071206=IEA} adult walking behavior, axon guidance, axonal fasciculation, cell adhesion, cellular protein localization, central nervous system myelination, cerebral cortex GABAergic interneuron migration, clustering of voltage-gated potassium channels, establishment of protein localization to juxtaparanode region of axon, learning, microtubule cytoskeleton organization, negative regulation of neuron differentiation, neuron migration, positive regulation of adenosine receptor signaling pathway, positive regulation of protein processing, receptor internalization, regulation of astrocyte differentiation, regulation of axon diameter, regulation of neuronal synaptic plasticity anchored to membrane, cell surface, integral to plasma membrane, juxtaparanode region of axon, myelin sheath, neuronal cell body, node of Ranvier, plasma membrane, synapse, voltage-gated potassium channel complex carbohydrate binding, glycoprotein binding, identical protein binding, protein self-association Human UniProtKB:P22063 CNTN3 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0031225=GO_REF:0000037, GO:0007155=GO_REF:0000037, GO:0007399=GO_REF:0000019} Q9P232 Contactin-3 protein 20130413 {GO:0005886=IEA, GO:0031225=IEA, GO:0007155=IEA, GO:0007399=IEA} cell adhesion, nervous system development anchored to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 CNTN4 UniProtKB UniProtKB {GO:0030424=PMID:14571131, GO:0005886=PMID:15106122, GO:0005576=GO_REF:0000039, GO:0031225=GO_REF:0000037, GO:0007409=PMID:14571131, GO:0031175=GO_REF:0000024, GO:0007399=PMID:15106122, GO:0007413=PMID:15106122, GO:0045665=PMID:14571131, GO:0007420=GO_REF:0000024, GO:0048167=PMID:15106122, GO:0007411=PMID:15106122, GO:0007158=PMID:14571131} Q8IWV2 Contactin-4 protein 20051129 {GO:0030424=NAS, GO:0005886=NAS, GO:0005576=IEA, GO:0031225=IEA, GO:0007409=TAS, GO:0031175=ISS, GO:0007399=IMP, GO:0007413=TAS, GO:0045665=IMP, GO:0007420=ISS, GO:0048167=TAS, GO:0007411=TAS, GO:0007158=TAS} axon guidance, axonal fasciculation, axonogenesis, brain development, negative regulation of neuron differentiation, nervous system development, neuron cell-cell adhesion, neuron projection development, regulation of synaptic plasticity anchored to membrane, axon, extracellular region, plasma membrane Human CNTN5 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000039, GO:0007605=GO_REF:0000019, GO:0031225=GO_REF:0000037, GO:0007155=GO_REF:0000037} O94779 Contactin-5 protein 20110516 {GO:0005737=IDA, GO:0005886=IEA, GO:0007605=IEA, GO:0031225=IEA, GO:0007155=IEA} cell adhesion, sensory perception of sound anchored to membrane, cytoplasm, plasma membrane Human CNTN6 Reactome UniProtKB {GO:0005886=GO_REF:0000039, GO:0007219=GO_REF:0000037, GO:0007411=Reactome:REACT_18266, GO:0031225=GO_REF:0000037, GO:0007417=PMID:9486763, GO:0007155=GO_REF:0000037} Q9UQ52 Contactin-6 protein 20091012 {GO:0005886=IEA, GO:0007219=IEA, GO:0007411=TAS, GO:0031225=IEA, GO:0007417=TAS, GO:0007155=IEA} Notch signaling pathway, axon guidance, cell adhesion, central nervous system development anchored to membrane, plasma membrane Human CNTNAP1 BHF-UCL UniProtKB {GO:0005515=PMID:17474147, GO:0017124=GO_REF:0000019, GO:0002175=GO_REF:0000024, GO:0030913=GO_REF:0000024, GO:0033270=GO_REF:0000024, GO:0007165=PMID:9118959, GO:0005887=PMID:9118959, GO:0007411=Reactome:REACT_18266, GO:0048812=GO_REF:0000024, GO:0005070=PMID:9118959, GO:0008076=GO_REF:0000024, GO:0007010=GO_REF:0000024, GO:0050884=GO_REF:0000019, GO:0050885=GO_REF:0000019, GO:0004872=PMID:9118959, GO:0008088=GO_REF:0000024, GO:0007155=GO_REF:0000037} P78357 Contactin-associated protein 1 protein 20110818 {GO:0005515=IPI, GO:0017124=IEA, GO:0002175=ISS, GO:0030913=ISS, GO:0033270=ISS, GO:0007165=TAS, GO:0005887=TAS, GO:0007411=TAS, GO:0048812=ISS, GO:0005070=TAS, GO:0008076=ISS, GO:0007010=ISS, GO:0050884=IEA, GO:0050885=IEA, GO:0004872=TAS, GO:0008088=ISS, GO:0007155=IEA} axon cargo transport, axon guidance, cell adhesion, cytoskeleton organization, neuromuscular process controlling balance, neuromuscular process controlling posture, neuron projection morphogenesis, paranodal junction assembly, protein localization to paranode region of axon, signal transduction integral to plasma membrane, paranode region of axon, voltage-gated potassium channel complex SH3 domain binding, SH3/SH2 adaptor activity, protein binding, receptor activity Human UniProtKB:O54991 CNTNAP2 BHF-UCL UniProtKB {GO:0030424=GO_REF:0000024, GO:0021987=PMID:18987363, GO:0008038=PMID:10624965, GO:0019226=PMID:11352571, GO:0031175=GO_REF:0000019, GO:0030425=GO_REF:0000024, GO:0021794=PMID:18179893, GO:0008076=PMID:10624965, GO:0043025=GO_REF:0000024, GO:0043204=GO_REF:0000024, GO:0007610=PMID:18179893, GO:0030673=PMID:19706678, GO:0007155=GO_REF:0000037, GO:0071109=PMID:18179893, GO:0005794=PMID:19166515, GO:0009986=PMID:19706678, GO:0044224=GO_REF:0000024, GO:0071625=PMID:19896112, GO:0021756=PMID:18179893, GO:0016020=PMID:10624965, GO:0007420=PMID:10624965, GO:0045163=GO_REF:0000024, GO:0021761=PMID:18179895, GO:0071205=GO_REF:0000019, GO:0016021=PMID:11352571, GO:0034613=GO_REF:0000024, GO:0019899=PMID:19166515, GO:0005769=PMID:19706678} Q9UHC6 Contactin-associated protein-like 2 protein 20110725 {GO:0030424=ISS, GO:0021987=IEP, GO:0008038=NAS, GO:0019226=NAS, GO:0031175=IEA, GO:0030425=ISS, GO:0021794=IEP, GO:0008076=IDA, GO:0043025=ISS, GO:0043204=ISS, GO:0007610=IMP, GO:0030673=IDA, GO:0007155=IEA, GO:0071109=IEP, GO:0005794=IDA, GO:0009986=IDA, GO:0044224=ISS, GO:0071625=IMP, GO:0021756=IEP, GO:0016020=IDA, GO:0007420=TAS, GO:0045163=ISS, GO:0021761=IEP, GO:0071205=IEA, GO:0016021=NAS, GO:0034613=ISS, GO:0019899=IPI, GO:0005769=IDA} behavior, brain development, cell adhesion, cellular protein localization, cerebral cortex development, clustering of voltage-gated potassium channels, limbic system development, neuron projection development, neuron recognition, protein localization to juxtaparanode region of axon, striatum development, superior temporal gyrus development, thalamus development, transmission of nerve impulse, vocalization behavior Golgi apparatus, axolemma, axon, cell surface, dendrite, early endosome, integral to membrane, juxtaparanode region of axon, membrane, neuronal cell body, perikaryon, voltage-gated potassium channel complex enzyme binding Human CNTNAP3 UniProtKB UniProtKB {GO:0008037=PMID:12093160, GO:0005886=GO_REF:0000039, GO:0005576=GO_REF:0000039, GO:0016021=PMID:12093160, GO:0007155=GO_REF:0000037} Q9BZ76 Contactin-associated protein-like 3 protein 20021104 {GO:0008037=NAS, GO:0005886=IEA, GO:0005576=IEA, GO:0016021=NAS, GO:0007155=IEA} cell adhesion, cell recognition extracellular region, integral to membrane, plasma membrane Human CNTNAP3B UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037} Q96NU0 Contactin-associated protein-like 3B protein 20130413 {GO:0016021=IEA, GO:0007155=IEA} cell adhesion integral to membrane Human UniProtKB-KW:KW-0812 CNTNAP4 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037} Q9C0A0 Contactin-associated protein-like 4 protein 20130413 {GO:0016021=IEA, GO:0007155=IEA} cell adhesion integral to membrane Human UniProtKB-KW:KW-0812 CNTRL Reactome UniProtKB {GO:0005515=PMID:17140400, GO:0005813=PMID:15337773, GO:0000086=Reactome:REACT_2203, GO:0000278=Reactome:REACT_152, GO:0005829=Reactome:REACT_121382, GO:0051301=GO_REF:0000037} Q7Z7A1 Centriolin protein 20121108 {GO:0005515=IPI, GO:0005813=IDA, GO:0000086=TAS, GO:0000278=TAS, GO:0005829=TAS, GO:0051301=IEA} G2/M transition of mitotic cell cycle, cell division, mitotic cell cycle centrosome, cytosol protein binding Human CNTROB HPA UniProtKB {GO:0005515=PMID:16275750, GO:0000910=PMID:16275750, GO:0005737=GO_REF:0000052, GO:0005813=GO_REF:0000052, GO:0007099=PMID:16275750, GO:0005814=PMID:16275750, GO:0051299=PMID:16275750, GO:0019904=PMID:11984006} Q8N137 Centrobin protein 20100326 {GO:0005515=IPI, GO:0000910=IMP, GO:0005737=IDA, GO:0005813=IDA, GO:0007099=IMP, GO:0005814=IDA, GO:0051299=IMP, GO:0019904=IPI} centriole replication, centrosome separation, cytokinesis centriole, centrosome, cytoplasm protein binding, protein domain specific binding Human COA5 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019} Q86WW8 Cytochrome c oxidase assembly factor 5 protein 20130413 {GO:0005739=IEA} mitochondrion Human Ensembl:ENSMUSP00000027286 COASY HPA UniProtKB {GO:0004595=PMID:11994049, GO:0015939=Reactome:REACT_11172, GO:0005730=GO_REF:0000052, GO:0006767=Reactome:REACT_11238, GO:0015937=PMID:11923312, GO:0005741=Reactome:REACT_11222, GO:0005634=GO_REF:0000052, GO:0005575=GO_REF:0000015, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0004140=PMID:11923312, GO:0006766=Reactome:REACT_11193, GO:0009108=Reactome:REACT_11218} Q13057 Bifunctional coenzyme A synthase protein 20100326 {GO:0004595=IDA, GO:0015939=TAS, GO:0005730=IDA, GO:0006767=TAS, GO:0015937=IDA, GO:0005741=TAS, GO:0005634=IDA, GO:0005575=ND, GO:0044281=TAS, GO:0005524=IEA, GO:0005737=IDA, GO:0004140=IDA, GO:0006766=TAS, GO:0009108=TAS} coenzyme A biosynthetic process, coenzyme biosynthetic process, pantothenate metabolic process, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cellular_component, cytoplasm, mitochondrial outer membrane, nucleolus, nucleus ATP binding, dephospho-CoA kinase activity, pantetheine-phosphate adenylyltransferase activity Human COBL BHF-UCL UniProtKB {GO:0030424=GO_REF:0000024, GO:0048471=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0033504=GO_REF:0000024, GO:0001757=GO_REF:0000024, GO:0005884=GO_REF:0000024, GO:0001843=GO_REF:0000024, GO:0003779=GO_REF:0000002, GO:0048565=GO_REF:0000024, GO:0044294=GO_REF:0000024, GO:0044295=GO_REF:0000024, GO:0001726=GO_REF:0000024, GO:0030425=GO_REF:0000024, GO:0001889=GO_REF:0000024, GO:0003785=GO_REF:0000024, GO:0000578=GO_REF:0000024, GO:0016020=GO_REF:0000024, GO:0051639=GO_REF:0000024, GO:0048669=GO_REF:0000024, GO:0030041=GO_REF:0000024, GO:0043025=GO_REF:0000024, GO:0030903=GO_REF:0000024, GO:0005938=GO_REF:0000024, GO:1900006=GO_REF:0000024} O75128 Protein cordon-bleu protein 20120808 {GO:0030424=ISS, GO:0048471=ISS, GO:0005886=IEA, GO:0033504=ISS, GO:0001757=ISS, GO:0005884=ISS, GO:0001843=ISS, GO:0003779=IEA, GO:0048565=ISS, GO:0044294=ISS, GO:0044295=ISS, GO:0001726=ISS, GO:0030425=ISS, GO:0001889=ISS, GO:0003785=ISS, GO:0000578=ISS, GO:0016020=ISS, GO:0051639=ISS, GO:0048669=ISS, GO:0030041=ISS, GO:0043025=ISS, GO:0030903=ISS, GO:0005938=ISS, GO:1900006=ISS} actin filament network formation, actin filament polymerization, collateral sprouting in absence of injury, digestive tract development, embryonic axis specification, floor plate development, liver development, neural tube closure, notochord development, positive regulation of dendrite development, somite specification actin filament, axon, axonal growth cone, cell cortex, dendrite, dendritic growth cone, membrane, neuronal cell body, perinuclear region of cytoplasm, plasma membrane, ruffle actin binding, actin monomer binding Human UniProtKB:Q5NBX1 COBLL1 InterPro UniProtKB {GO:0003779=GO_REF:0000002} Q53SF7 Cordon-bleu protein-like 1 protein 20130413 {GO:0003779=IEA} actin binding Human InterPro:IPR003124 COCH UniProtKB UniProtKB {GO:0005515=PMID:21886777, GO:0008360=PMID:21886777, GO:0007605=GO_REF:0000019, GO:0005578=GO_REF:0000039} O43405 Cochlin protein 20120615 {GO:0005515=IPI, GO:0008360=IMP, GO:0007605=IEA, GO:0005578=IEA} regulation of cell shape, sensory perception of sound proteinaceous extracellular matrix protein binding Human COG1 IntAct UniProtKB {GO:0005515=PMID:15047703, GO:0005794=PMID:11980916, GO:0000139=GO_REF:0000039, GO:0007030=PMID:11980916, GO:0006891=PMID:11980916, GO:0017119=PMID:15047703, GO:0015031=GO_REF:0000037} Q8WTW3 Conserved oligomeric Golgi complex subunit 1 protein 20130415 {GO:0005515=IPI, GO:0005794=IDA, GO:0000139=IEA, GO:0007030=NAS, GO:0006891=NAS, GO:0017119=IDA, GO:0015031=IEA} Golgi organization, intra-Golgi vesicle-mediated transport, protein transport Golgi apparatus, Golgi membrane, Golgi transport complex protein binding Human UniProtKB:Q9H9E3 COG2 IntAct UniProtKB {GO:0005515=PMID:15047703, GO:0009312=PMID:7962052, GO:0005795=PMID:7962052, GO:0000139=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0008565=PMID:7962052, GO:0007030=PMID:7962052, GO:0017119=PMID:15047703, GO:0006891=PMID:7962052, GO:0006486=PMID:7962052, GO:0015031=GO_REF:0000002, GO:0006886=PMID:7962052} Q14746 Conserved oligomeric Golgi complex subunit 2 protein 20130415 {GO:0005515=IPI, GO:0009312=TAS, GO:0005795=IDA, GO:0000139=IEA, GO:0016020=IEA, GO:0008565=IMP, GO:0007030=IMP, GO:0017119=IDA, GO:0006891=IMP, GO:0006486=TAS, GO:0015031=IEA, GO:0006886=TAS} Golgi organization, intra-Golgi vesicle-mediated transport, intracellular protein transport, oligosaccharide biosynthetic process, protein glycosylation, protein transport Golgi membrane, Golgi stack, Golgi transport complex, membrane protein binding, protein transporter activity Human UniProtKB:Q9H9E3 COG3 HPA UniProtKB {GO:0005515=PMID:19536132, GO:0005801=GO_REF:0000002, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0033365=PMID:16420527, GO:0006890=PMID:16420527, GO:0005730=GO_REF:0000052, GO:0050821=PMID:16420527, GO:0006891=PMID:11929878, GO:0005634=GO_REF:0000052, GO:0006886=GO_REF:0000002, GO:0006888=PMID:11929878, GO:0005737=GO_REF:0000052, GO:0032580=GO_REF:0000039, GO:0008565=PMID:11929878, GO:0017119=PMID:15047703, GO:0006486=PMID:16420527} Q96JB2 Conserved oligomeric Golgi complex subunit 3 protein 20110516 {GO:0005515=IPI, GO:0005801=IEA, GO:0005794=IDA, GO:0005886=IDA, GO:0033365=IMP, GO:0006890=IMP, GO:0005730=IDA, GO:0050821=IMP, GO:0006891=IDA, GO:0005634=IDA, GO:0006886=IEA, GO:0006888=IDA, GO:0005737=IDA, GO:0032580=IEA, GO:0008565=IDA, GO:0017119=IDA, GO:0006486=IMP} ER to Golgi vesicle-mediated transport, intra-Golgi vesicle-mediated transport, intracellular protein transport, protein glycosylation, protein localization to organelle, protein stabilization, retrograde vesicle-mediated transport, Golgi to ER Golgi apparatus, Golgi cisterna membrane, Golgi transport complex, cis-Golgi network, cytoplasm, nucleolus, nucleus, plasma membrane protein binding, protein transporter activity Human COG4 IntAct UniProtKB {GO:0005515=PMID:15047703, GO:0048213=PMID:19536132, GO:0000139=GO_REF:0000039, GO:0006890=PMID:19536132, GO:0007030=PMID:19536132, GO:0017119=PMID:15047703, GO:0015031=GO_REF:0000037} Q9H9E3 Conserved oligomeric Golgi complex subunit 4 protein 20130415 {GO:0005515=IPI, GO:0048213=IMP, GO:0000139=IEA, GO:0006890=IMP, GO:0007030=IMP, GO:0017119=IDA, GO:0015031=IEA} Golgi organization, Golgi vesicle prefusion complex stabilization, protein transport, retrograde vesicle-mediated transport, Golgi to ER Golgi membrane, Golgi transport complex protein binding Human UniProtKB:Q9UP83 COG5 HPA UniProtKB {GO:0005515=PMID:15047703, GO:0003674=GO_REF:0000015, GO:0005794=GO_REF:0000052, GO:0000139=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0006891=PMID:9792665, GO:0017119=PMID:15047703, GO:0005634=GO_REF:0000052, GO:0015031=GO_REF:0000037, GO:0005829=GO_REF:0000039} Q9UP83 Conserved oligomeric Golgi complex subunit 5 protein 20100326 {GO:0005515=IPI, GO:0003674=ND, GO:0005794=IDA, GO:0000139=IEA, GO:0005730=IDA, GO:0006891=NAS, GO:0017119=IDA, GO:0005634=IDA, GO:0015031=IEA, GO:0005829=IEA} intra-Golgi vesicle-mediated transport, protein transport Golgi apparatus, Golgi membrane, Golgi transport complex, cytosol, nucleolus, nucleus molecular_function, protein binding Human COG6 UniProtKB UniProtKB {GO:0070085=PMID:20605848, GO:0000139=GO_REF:0000039, GO:0017119=PMID:15047703, GO:0006891=GO_REF:0000002, GO:0015031=GO_REF:0000037} Q9Y2V7 Conserved oligomeric Golgi complex subunit 6 protein 20120618 {GO:0070085=IMP, GO:0000139=IEA, GO:0017119=IDA, GO:0006891=IEA, GO:0015031=IEA} glycosylation, intra-Golgi vesicle-mediated transport, protein transport Golgi membrane, Golgi transport complex Human COG7 IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0005794=PMID:11980916, GO:0033365=PMID:16420527, GO:0000139=GO_REF:0000039, GO:0034067=PMID:16510524, GO:0006890=PMID:16420527, GO:0050821=PMID:16420527, GO:0017119=PMID:15047703, GO:0006486=PMID:16420527, GO:0006886=PMID:15107842} P83436 Conserved oligomeric Golgi complex subunit 7 protein 20130415 {GO:0005515=IPI, GO:0005794=IDA, GO:0033365=IMP, GO:0000139=IEA, GO:0034067=IMP, GO:0006890=IMP, GO:0050821=IMP, GO:0017119=IDA, GO:0006486=IMP, GO:0006886=IMP} intracellular protein transport, protein glycosylation, protein localization to Golgi apparatus, protein localization to organelle, protein stabilization, retrograde vesicle-mediated transport, Golgi to ER Golgi apparatus, Golgi membrane, Golgi transport complex protein binding Human UniProtKB:P70191 COG8 UniProtKB UniProtKB {GO:0000139=GO_REF:0000039, GO:0017119=PMID:15047703, GO:0015031=GO_REF:0000037} Q96MW5 Conserved oligomeric Golgi complex subunit 8 protein 20071221 {GO:0000139=IEA, GO:0017119=IDA, GO:0015031=IEA} protein transport Golgi membrane, Golgi transport complex Human COIL BHF-UCL UniProtKB {GO:0005515=PMID:21920476, GO:0001674=GO_REF:0000019, GO:0015030=PMID:16687569, GO:0005730=PMID:12757932, GO:0015036=GO_REF:0000019, GO:0005634=PMID:7971277, GO:0005654=PMID:12757932, GO:0008022=PMID:12757932, GO:0042802=PMID:16713569} P38432 Coilin protein 20091118 {GO:0005515=IPI, GO:0001674=IEA, GO:0015030=IDA, GO:0005730=IDA, GO:0015036=IEA, GO:0005634=TAS, GO:0005654=IDA, GO:0008022=IPI, GO:0042802=IPI} Cajal body, female germ cell nucleus, nucleolus, nucleoplasm, nucleus disulfide oxidoreductase activity, identical protein binding, protein C-terminus binding, protein binding Human COL10A1 ENSEMBL UniProtKB {GO:0001501=PMID:8554571, GO:0005581=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0005576=Reactome:REACT_150398, GO:0005938=GO_REF:0000019, GO:0046872=GO_REF:0000037} Q5QPC8 Collagen alpha-1(X) chain protein 20130413 {GO:0001501=TAS, GO:0005581=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0030574=TAS, GO:0005788=TAS, GO:0005576=TAS, GO:0005938=IEA, GO:0046872=IEA} collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, skeletal system development cell cortex, collagen, endoplasmic reticulum lumen, extracellular region metal ion binding Human Ensembl:ENSMUSP00000101150 COL11A1 Reactome UniProtKB {GO:0042472=GO_REF:0000019, GO:0055010=GO_REF:0000019, GO:0005592=PMID:3182841, GO:0007605=PMID:10573014, GO:0050840=PMID:3182841, GO:0005576=Reactome:REACT_150444, GO:0048704=GO_REF:0000019, GO:0006029=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0022617=Reactome:REACT_118572, GO:0002063=GO_REF:0000019, GO:0001502=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0030199=PMID:3182841, GO:0050910=PMID:10889003, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0030674=PMID:10486316, GO:0007601=PMID:8872475, GO:0005201=PMID:10486316} P12107 Collagen alpha-1(XI) chain protein 20130301 {GO:0042472=IEA, GO:0055010=IEA, GO:0005592=IDA, GO:0007605=IMP, GO:0050840=NAS, GO:0005576=TAS, GO:0048704=IEA, GO:0006029=IEA, GO:0046872=IEA, GO:0022617=TAS, GO:0002063=IEA, GO:0001502=IEA, GO:0030198=TAS, GO:0030199=NAS, GO:0050910=IMP, GO:0030574=TAS, GO:0005788=TAS, GO:0030674=NAS, GO:0007601=IMP, GO:0005201=NAS} cartilage condensation, chondrocyte development, collagen catabolic process, collagen fibril organization, detection of mechanical stimulus involved in sensory perception of sound, embryonic skeletal system morphogenesis, extracellular matrix disassembly, extracellular matrix organization, inner ear morphogenesis, proteoglycan metabolic process, sensory perception of sound, ventricular cardiac muscle tissue morphogenesis, visual perception collagen type XI, endoplasmic reticulum lumen, extracellular region extracellular matrix binding, extracellular matrix structural constituent, metal ion binding, protein binding, bridging Human COL11A2 ENSEMBL UniProtKB {GO:0005581=GO_REF:0000038, GO:0005592=GO_REF:0000019, GO:0051216=PMID:9188673, GO:0007605=GO_REF:0000019, GO:0048705=GO_REF:0000019, GO:0005576=Reactome:REACT_150444, GO:0046872=GO_REF:0000037, GO:0001501=PMID:7859284, GO:0001894=GO_REF:0000019, GO:0001503=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0030020=PMID:8838804, GO:0002062=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0030199=GO_REF:0000019, GO:0030574=Reactome:REACT_150401, GO:0005840=GO_REF:0000038, GO:0005788=Reactome:REACT_121366, GO:0060021=PMID:12673280, GO:0030674=PMID:10677296, GO:0005201=GO_REF:0000002, GO:0060023=PMID:10677296} Q4VXY6 Collagen type XI alpha 2 protein 20130413 {GO:0005581=IEA, GO:0005592=IEA, GO:0051216=IMP, GO:0007605=IEA, GO:0048705=IEA, GO:0005576=TAS, GO:0046872=IEA, GO:0001501=NAS, GO:0001894=IEA, GO:0001503=IEA, GO:0022617=TAS, GO:0030020=NAS, GO:0002062=IEA, GO:0030198=TAS, GO:0030199=IEA, GO:0030574=TAS, GO:0005840=IEA, GO:0005788=TAS, GO:0060021=IMP, GO:0030674=NAS, GO:0005201=IEA, GO:0060023=IMP} cartilage development, chondrocyte differentiation, collagen catabolic process, collagen fibril organization, extracellular matrix disassembly, extracellular matrix organization, ossification, palate development, sensory perception of sound, skeletal system development, skeletal system morphogenesis, soft palate development, tissue homeostasis collagen, collagen type XI, endoplasmic reticulum lumen, extracellular region, ribosome extracellular matrix structural constituent, extracellular matrix structural constituent conferring tensile strength, metal ion binding, protein binding, bridging Human Ensembl:ENSMUSP00000084772 COL12A1 Reactome UniProtKB {GO:0001501=PMID:3476925, GO:0022617=Reactome:REACT_118572, GO:0030020=PMID:1427837, GO:0030198=Reactome:REACT_118779, GO:0030199=PMID:1427837, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0005595=PMID:1427837, GO:0005576=Reactome:REACT_150466, GO:0007155=GO_REF:0000037} Q99715 Collagen alpha-1(XII) chain protein 20130301 {GO:0001501=TAS, GO:0022617=TAS, GO:0030020=NAS, GO:0030198=TAS, GO:0030199=NAS, GO:0030574=TAS, GO:0005788=TAS, GO:0005595=NAS, GO:0005576=TAS, GO:0007155=IEA} cell adhesion, collagen catabolic process, collagen fibril organization, extracellular matrix disassembly, extracellular matrix organization, skeletal system development collagen type XII, endoplasmic reticulum lumen, extracellular region extracellular matrix structural constituent conferring tensile strength Human COL13A1 Reactome UniProtKB {GO:0005515=PMID:11956183, GO:0005886=GO_REF:0000039, GO:0005576=Reactome:REACT_150341, GO:0005600=PMID:2459707, GO:0030154=GO_REF:0000037, GO:0001958=GO_REF:0000024, GO:0016337=PMID:10865988, GO:0022617=Reactome:REACT_118572, GO:0007160=PMID:11956183, GO:0030198=Reactome:REACT_118779, GO:0005911=GO_REF:0000019, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121254, GO:0016021=GO_REF:0000037, GO:0008201=PMID:11956183, GO:0005201=GO_REF:0000029, GO:0001763=GO_REF:0000024} Q5TAT6 Collagen alpha-1(XIII) chain protein 20130301 {GO:0005515=IPI, GO:0005886=IEA, GO:0005576=TAS, GO:0005600=TAS, GO:0030154=IEA, GO:0001958=ISS, GO:0016337=IEP, GO:0022617=TAS, GO:0007160=IPI, GO:0030198=TAS, GO:0005911=IEA, GO:0030574=TAS, GO:0005788=TAS, GO:0016021=IEA, GO:0008201=IDA, GO:0005201=NAS, GO:0001763=ISS} cell differentiation, cell-cell adhesion, cell-matrix adhesion, collagen catabolic process, endochondral ossification, extracellular matrix disassembly, extracellular matrix organization, morphogenesis of a branching structure cell-cell junction, collagen type XIII, endoplasmic reticulum lumen, extracellular region, integral to membrane, plasma membrane extracellular matrix structural constituent, heparin binding, protein binding Human COL14A1 BHF-UCL UniProtKB {GO:0005581=PMID:9427527, GO:0005518=PMID:2187872, GO:0005578=PMID:2187872, GO:0005596=PMID:9427527, GO:0005576=Reactome:REACT_121366, GO:0031012=PMID:22261194, GO:0016337=PMID:9427527, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0030199=PMID:2187872, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0030674=PMID:9427527, GO:0005201=PMID:9427527} Q05707 Collagen alpha-1(XIV) chain protein 20120228 {GO:0005581=NAS, GO:0005518=NAS, GO:0005578=NAS, GO:0005596=NAS, GO:0005576=TAS, GO:0031012=ISS, GO:0016337=NAS, GO:0022617=TAS, GO:0030198=TAS, GO:0030199=NAS, GO:0030574=TAS, GO:0005788=TAS, GO:0030674=NAS, GO:0005201=NAS} cell-cell adhesion, collagen catabolic process, collagen fibril organization, extracellular matrix disassembly, extracellular matrix organization collagen, collagen type XIV, endoplasmic reticulum lumen, extracellular matrix, extracellular region, proteinaceous extracellular matrix collagen binding, extracellular matrix structural constituent, protein binding, bridging colocalizes_with Human UniProtKB:F1S285 COL15A1 BHF-UCL UniProtKB {GO:0005576=Reactome:REACT_150289, GO:0001525=GO_REF:0000037, GO:0005582=PMID:9651385, GO:0030154=GO_REF:0000037, GO:0005604=GO_REF:0000019, GO:0031012=PMID:22261194, GO:0007165=PMID:10891348, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0016021=PMID:10891348, GO:0007155=PMID:9651385, GO:0005201=PMID:9651385} P39059 Collagen alpha-1(XV) chain protein 20120228 {GO:0005576=TAS, GO:0001525=IEA, GO:0005582=TAS, GO:0030154=IEA, GO:0005604=IEA, GO:0031012=ISS, GO:0007165=NAS, GO:0022617=TAS, GO:0030198=TAS, GO:0030574=TAS, GO:0005788=TAS, GO:0016021=NAS, GO:0007155=IC, GO:0005201=IC} angiogenesis, cell adhesion, cell differentiation, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, signal transduction basement membrane, collagen type XV, endoplasmic reticulum lumen, extracellular matrix, extracellular region, integral to membrane extracellular matrix structural constituent colocalizes_with Human UniProtKB:F1SSE8 COL16A1 Reactome UniProtKB {GO:0005515=PMID:15165854, GO:0007565=PMID:1284248, GO:0005178=PMID:16754661, GO:0022617=Reactome:REACT_118572, GO:0071230=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0007229=PMID:16754661, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0005576=Reactome:REACT_121366, GO:0007155=PMID:16754661, GO:0005597=PMID:1284248} Q07092 Collagen alpha-1(XVI) chain protein 20130301 {GO:0005515=IPI, GO:0007565=TAS, GO:0005178=IDA, GO:0022617=TAS, GO:0071230=IEA, GO:0030198=TAS, GO:0007229=TAS, GO:0030574=TAS, GO:0005788=TAS, GO:0005576=TAS, GO:0007155=IDA, GO:0005597=TAS} cell adhesion, cellular response to amino acid stimulus, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, female pregnancy, integrin-mediated signaling pathway collagen type XVI, endoplasmic reticulum lumen, extracellular region integrin binding, protein binding Human COL17A1 Reactome UniProtKB {GO:0005515=PMID:12482924, GO:0030056=PMID:12482924, GO:0005581=GO_REF:0000037, GO:0005886=Reactome:REACT_150217, GO:0034329=Reactome:REACT_20676, GO:0005576=Reactome:REACT_150205, GO:0005604=GO_REF:0000039, GO:0007160=PMID:9012408, GO:0008544=PMID:9012408, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0005911=PMID:9012408, GO:0005887=PMID:9012408, GO:0030574=Reactome:REACT_150401, GO:0031581=Reactome:REACT_20537, GO:0005788=Reactome:REACT_121254} Q9UMD9 Collagen alpha-1(XVII) chain protein 20130213 {GO:0005515=IPI, GO:0030056=IDA, GO:0005581=IEA, GO:0005886=TAS, GO:0034329=TAS, GO:0005576=TAS, GO:0005604=IEA, GO:0007160=TAS, GO:0008544=TAS, GO:0022617=TAS, GO:0030198=TAS, GO:0005911=TAS, GO:0005887=TAS, GO:0030574=TAS, GO:0031581=TAS, GO:0005788=TAS} cell junction assembly, cell-matrix adhesion, collagen catabolic process, epidermis development, extracellular matrix disassembly, extracellular matrix organization, hemidesmosome assembly basement membrane, cell-cell junction, collagen, endoplasmic reticulum lumen, extracellular region, hemidesmosome, integral to plasma membrane, plasma membrane protein binding Human COL18A1 IntAct UniProtKB {GO:0005581=GO_REF:0000037, GO:0008284=GO_REF:0000019, GO:0008285=PMID:9008168, GO:0030335=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0005576=Reactome:REACT_150437, GO:0001525=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0042802=PMID:16269408, GO:0005604=GO_REF:0000019, GO:0031012=GO_REF:0000002, GO:0022617=Reactome:REACT_118572, GO:0001886=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0005198=GO_REF:0000002, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0009887=PMID:10942434, GO:0007155=GO_REF:0000037, GO:0007601=PMID:10942434} P39060 Collagen alpha-1(XVIII) chain protein 20130415 {GO:0005581=IEA, GO:0008284=IEA, GO:0008285=TAS, GO:0030335=IEA, GO:0043065=IEA, GO:0005576=TAS, GO:0001525=IEA, GO:0046872=IEA, GO:0042802=IPI, GO:0005604=IEA, GO:0031012=IEA, GO:0022617=TAS, GO:0001886=IEA, GO:0030198=TAS, GO:0005198=IEA, GO:0030574=TAS, GO:0005788=TAS, GO:0009887=TAS, GO:0007155=IEA, GO:0007601=TAS} angiogenesis, cell adhesion, collagen catabolic process, endothelial cell morphogenesis, extracellular matrix disassembly, extracellular matrix organization, negative regulation of cell proliferation, organ morphogenesis, positive regulation of apoptotic process, positive regulation of cell migration, positive regulation of cell proliferation, visual perception basement membrane, collagen, endoplasmic reticulum lumen, extracellular matrix, extracellular region identical protein binding, metal ion binding, structural molecule activity Human UniProtKB:P39060 COL19A1 Reactome UniProtKB {GO:0005581=PMID:7775380, GO:0005578=PMID:1639419, GO:0005576=Reactome:REACT_150411, GO:0030154=GO_REF:0000037, GO:0016337=PMID:1639419, GO:0001501=PMID:9143499, GO:0022617=Reactome:REACT_118572, GO:0007519=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0030674=PMID:1639419, GO:0007155=PMID:7775380, GO:0005201=PMID:7775380} Q14993 Collagen alpha-1(XIX) chain protein 20130301 {GO:0005581=NAS, GO:0005578=NAS, GO:0005576=TAS, GO:0030154=IEA, GO:0016337=NAS, GO:0001501=TAS, GO:0022617=TAS, GO:0007519=IEA, GO:0030198=TAS, GO:0030574=TAS, GO:0005788=TAS, GO:0030674=NAS, GO:0007155=NAS, GO:0005201=NAS} cell adhesion, cell differentiation, cell-cell adhesion, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, skeletal muscle tissue development, skeletal system development collagen, endoplasmic reticulum lumen, extracellular region, proteinaceous extracellular matrix extracellular matrix structural constituent, protein binding, bridging Human COL1A1 BHF-UCL UniProtKB {GO:0005515=PMID:14749390, GO:0042542=GO_REF:0000019, GO:0034504=PMID:20018240, GO:0034505=PMID:17118335, GO:0071300=GO_REF:0000019, GO:0007605=PMID:17489845, GO:0090263=PMID:20018240, GO:0010718=PMID:20018240, GO:0048706=PMID:18553566, GO:0010812=GO_REF:0000019, GO:0043434=GO_REF:0000019, GO:0071560=GO_REF:0000019, GO:0050900=Reactome:REACT_12051, GO:0015031=GO_REF:0000019, GO:0051591=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0042802=PMID:17211858, GO:0005584=PMID:14976317, GO:0070208=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0071230=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0060351=GO_REF:0000019, GO:0030199=PMID:17211858, GO:0030574=Reactome:REACT_150401, GO:0030335=PMID:20018240, GO:0001568=PMID:17211858, GO:0048407=PMID:8900172, GO:0007584=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0031960=GO_REF:0000019, GO:0005576=Reactome:REACT_150470, GO:0001649=GO_REF:0000019, GO:0031012=PMID:22261194, GO:0001958=GO_REF:0000019, GO:0001501=PMID:8097422, GO:0001957=GO_REF:0000019, GO:0060346=GO_REF:0000019, GO:0060325=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0005788=Reactome:REACT_121366, GO:0043589=PMID:17211858, GO:0032964=PMID:15095409, GO:0045893=PMID:20018240, GO:0071260=GO_REF:0000019, GO:0007601=PMID:17557158, GO:0005201=GO_REF:0000019} P02452 Collagen alpha-1(I) chain protein 20120228 {GO:0005515=IPI, GO:0042542=IEA, GO:0034504=IDA, GO:0034505=IMP, GO:0071300=IEA, GO:0007605=IMP, GO:0090263=IDA, GO:0010718=IDA, GO:0048706=IMP, GO:0010812=IEA, GO:0043434=IEA, GO:0071560=IEA, GO:0050900=TAS, GO:0015031=IEA, GO:0051591=IEA, GO:0046872=IEA, GO:0042802=IDA, GO:0005584=IMP, GO:0070208=IEA, GO:0022617=TAS, GO:0071230=IEA, GO:0030198=TAS, GO:0060351=IEA, GO:0030199=IMP, GO:0030574=TAS, GO:0030335=IDA, GO:0001568=IMP, GO:0048407=IDA, GO:0007584=IEA, GO:0030168=TAS, GO:0031960=IEA, GO:0005576=TAS, GO:0001649=IEA, GO:0031012=ISS, GO:0001958=IEA, GO:0001501=IMP, GO:0001957=IEA, GO:0060346=IEA, GO:0060325=IEA, GO:0007596=TAS, GO:0005788=TAS, GO:0043589=IMP, GO:0032964=IMP, GO:0045893=IDA, GO:0071260=IEA, GO:0007601=IMP, GO:0005201=IEA} blood coagulation, blood vessel development, bone trabecula formation, cartilage development involved in endochondral bone morphogenesis, cellular response to amino acid stimulus, cellular response to mechanical stimulus, cellular response to retinoic acid, cellular response to transforming growth factor beta stimulus, collagen biosynthetic process, collagen catabolic process, collagen fibril organization, embryonic skeletal system development, endochondral ossification, extracellular matrix disassembly, extracellular matrix organization, face morphogenesis, intramembranous ossification, leukocyte migration, negative regulation of cell-substrate adhesion, osteoblast differentiation, platelet activation, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of cell migration, positive regulation of epithelial to mesenchymal transition, positive regulation of transcription, DNA-dependent, protein heterotrimerization, protein localization to nucleus, protein transport, response to cAMP, response to corticosteroid stimulus, response to hydrogen peroxide, response to nutrient, response to peptide hormone stimulus, sensory perception of sound, skeletal system development, skin morphogenesis, tooth mineralization, visual perception collagen type I, endoplasmic reticulum lumen, extracellular matrix, extracellular region extracellular matrix structural constituent, identical protein binding, metal ion binding, platelet-derived growth factor binding, protein binding colocalizes_with Human UniProtKB:Q1HNM7 COL1A2 Reactome UniProtKB {GO:0005515=PMID:18375391, GO:0046332=GO_REF:0000019, GO:0007266=PMID:17217948, GO:0050900=Reactome:REACT_12051, GO:0005615=PMID:18375391, GO:0046872=GO_REF:0000037, GO:0042802=PMID:17211858, GO:0005584=PMID:18375391, GO:0070208=GO_REF:0000019, GO:0071230=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0030199=PMID:17211858, GO:0030574=Reactome:REACT_150401, GO:0042476=PMID:1740554, GO:0007179=PMID:17217948, GO:0030674=PMID:18375391, GO:0001568=PMID:17211858, GO:0048407=PMID:8900172, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_150470, GO:0001501=PMID:18375391, GO:0007596=Reactome:REACT_604, GO:0008217=PMID:17334644, GO:0005788=Reactome:REACT_121366, GO:0043589=PMID:17211858, GO:0005201=PMID:8982144} P08123 Collagen alpha-2(I) chain protein 20130301 {GO:0005515=IPI, GO:0046332=IEA, GO:0007266=IDA, GO:0050900=TAS, GO:0005615=IDA, GO:0046872=IEA, GO:0042802=IDA, GO:0005584=IDA, GO:0070208=IEA, GO:0071230=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0030199=IMP, GO:0030574=TAS, GO:0042476=NAS, GO:0007179=IDA, GO:0030674=IMP, GO:0001568=IMP, GO:0048407=IDA, GO:0030168=TAS, GO:0005576=TAS, GO:0001501=IMP, GO:0007596=TAS, GO:0008217=IMP, GO:0005788=TAS, GO:0043589=IMP, GO:0005201=NAS} Rho protein signal transduction, blood coagulation, blood vessel development, cellular response to amino acid stimulus, collagen catabolic process, collagen fibril organization, extracellular matrix disassembly, extracellular matrix organization, leukocyte migration, odontogenesis, platelet activation, protein heterotrimerization, regulation of blood pressure, skeletal system development, skin morphogenesis, transforming growth factor beta receptor signaling pathway collagen type I, endoplasmic reticulum lumen, extracellular region, extracellular space SMAD binding, extracellular matrix structural constituent, identical protein binding, metal ion binding, platelet-derived growth factor binding, protein binding, protein binding, bridging Human COL20A1 Reactome UniProtKB {GO:0005581=GO_REF:0000037, GO:0030198=Reactome:REACT_118779, GO:0005788=Reactome:REACT_121366, GO:0005576=Reactome:REACT_121366, GO:0005615=GO_REF:0000039} Q9P218 Collagen alpha-1(XX) chain protein 20130301 {GO:0005581=IEA, GO:0030198=TAS, GO:0005788=TAS, GO:0005576=TAS, GO:0005615=IEA} extracellular matrix organization collagen, endoplasmic reticulum lumen, extracellular region, extracellular space Human COL23A1 Reactome UniProtKB {GO:0005581=GO_REF:0000037, GO:0022617=Reactome:REACT_118572, GO:0005886=Reactome:REACT_120755, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0016021=GO_REF:0000037} Q86Y22 Collagen alpha-1(XXIII) chain protein 20130301 {GO:0005581=IEA, GO:0022617=TAS, GO:0005886=TAS, GO:0030198=TAS, GO:0030574=TAS, GO:0005788=TAS, GO:0016021=IEA} collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization collagen, endoplasmic reticulum lumen, integral to membrane, plasma membrane Human COL25A1 Reactome UniProtKB {GO:0005581=GO_REF:0000037, GO:0001540=PMID:11927537, GO:0022617=Reactome:REACT_118572, GO:0005886=Reactome:REACT_150355, GO:0030198=Reactome:REACT_118779, GO:0005887=PMID:11927537, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121254, GO:0005576=Reactome:REACT_150355, GO:0016021=PMID:11927537, GO:0008201=PMID:15522881, GO:0005615=PMID:11927537} Q9BXS0 Collagen alpha-1(XXV) chain protein 20130301 {GO:0005581=IEA, GO:0001540=IDA, GO:0022617=TAS, GO:0005886=TAS, GO:0030198=TAS, GO:0005887=IDA, GO:0030574=TAS, GO:0005788=TAS, GO:0005576=TAS, GO:0016021=NAS, GO:0008201=IDA, GO:0005615=IDA} collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization collagen, endoplasmic reticulum lumen, extracellular region, extracellular space, integral to membrane, integral to plasma membrane, plasma membrane beta-amyloid binding, heparin binding Human COL27A1 Reactome UniProtKB {GO:0030198=Reactome:REACT_118779, GO:0005788=Reactome:REACT_121366, GO:0005576=Reactome:REACT_150338, GO:0005583=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005201=GO_REF:0000002} Q8IZC6 Collagen alpha-1(XXVII) chain protein 20130301 {GO:0030198=TAS, GO:0005788=TAS, GO:0005576=TAS, GO:0005583=IEA, GO:0046872=IEA, GO:0005201=IEA} extracellular matrix organization endoplasmic reticulum lumen, extracellular region, fibrillar collagen extracellular matrix structural constituent, metal ion binding Human COL2A1 BHF-UCL UniProtKB {GO:0010468=GO_REF:0000019, GO:0071773=GO_REF:0000019, GO:0051216=PMID:7550321, GO:0007605=PMID:16752401, GO:0005615=GO_REF:0000019, GO:0005585=PMID:8660302, GO:0046872=GO_REF:0000037, GO:0042802=PMID:2587267, GO:0030020=PMID:8660302, GO:0001894=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0002062=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0030199=PMID:1429602, GO:0060351=GO_REF:0000019, GO:0030574=Reactome:REACT_150401, GO:0060021=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0042472=GO_REF:0000019, GO:0071599=GO_REF:0000019, GO:0048407=PMID:8900172, GO:0005576=Reactome:REACT_150444, GO:0006029=GO_REF:0000019, GO:0007417=GO_REF:0000019, GO:0005604=GO_REF:0000019, GO:0003007=GO_REF:0000019, GO:0001958=GO_REF:0000019, GO:0001501=PMID:1429602, GO:0001502=GO_REF:0000019, GO:0060272=PMID:16752401, GO:0060174=GO_REF:0000019, GO:0005788=Reactome:REACT_121366, GO:0030903=GO_REF:0000019, GO:0007601=PMID:16752401} P02458 Collagen alpha-1(II) chain protein 20080919 {GO:0010468=IEA, GO:0071773=IEA, GO:0051216=TAS, GO:0007605=IMP, GO:0005615=IEA, GO:0005585=IDA, GO:0046872=IEA, GO:0042802=NAS, GO:0030020=IC, GO:0001894=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0002062=IEA, GO:0007411=TAS, GO:0030199=IMP, GO:0060351=IEA, GO:0030574=TAS, GO:0060021=IEA, GO:0043066=IEA, GO:0042472=IEA, GO:0071599=IEA, GO:0048407=IDA, GO:0005576=TAS, GO:0006029=IEA, GO:0007417=IEA, GO:0005604=IEA, GO:0003007=IEA, GO:0001958=IEA, GO:0001501=IMP, GO:0001502=IEA, GO:0060272=IMP, GO:0060174=IEA, GO:0005788=TAS, GO:0030903=IEA, GO:0007601=IMP} axon guidance, cartilage condensation, cartilage development, cartilage development involved in endochondral bone morphogenesis, cellular response to BMP stimulus, central nervous system development, chondrocyte differentiation, collagen catabolic process, collagen fibril organization, embryonic skeletal joint morphogenesis, endochondral ossification, extracellular matrix disassembly, extracellular matrix organization, heart morphogenesis, inner ear morphogenesis, limb bud formation, negative regulation of apoptotic process, notochord development, otic vesicle development, palate development, proteoglycan metabolic process, regulation of gene expression, sensory perception of sound, skeletal system development, tissue homeostasis, visual perception basement membrane, collagen type II, endoplasmic reticulum lumen, extracellular region, extracellular space extracellular matrix structural constituent conferring tensile strength, identical protein binding, metal ion binding, platelet-derived growth factor binding Human GO:0005594 COL3A1 Reactome UniProtKB {GO:0005515=PMID:2839553, GO:0005581=GO_REF:0000002, GO:0005586=PMID:7487954, GO:0046332=GO_REF:0000019, GO:0005615=PMID:7487954, GO:0046872=GO_REF:0000037, GO:0007507=PMID:7546986, GO:0022617=Reactome:REACT_118572, GO:0071230=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0007411=Reactome:REACT_18266, GO:0030199=PMID:1672129, GO:0030574=Reactome:REACT_150401, GO:0007179=PMID:16360482, GO:0043206=PMID:14970208, GO:0034097=PMID:9076960, GO:0009314=PMID:14736764, GO:0001568=GO_REF:0000019, GO:0048407=PMID:8900172, GO:0030168=PMID:9573018, GO:0005576=Reactome:REACT_150439, GO:0048565=GO_REF:0000019, GO:0031012=PMID:7487954, GO:0001501=GO_REF:0000019, GO:0005178=PMID:9573018, GO:0018149=PMID:16754721, GO:0007160=PMID:16912226, GO:0050777=PMID:16754721, GO:0007229=PMID:14970208, GO:0042060=PMID:1466622, GO:0005788=Reactome:REACT_121366, GO:0043588=PMID:9036918, GO:0032964=PMID:2981879, GO:0005201=PMID:7487954} P02461 Collagen alpha-1(III) chain protein 20130301 {GO:0005515=IPI, GO:0005581=IEA, GO:0005586=IMP, GO:0046332=IEA, GO:0005615=IDA, GO:0046872=IEA, GO:0007507=IMP, GO:0022617=TAS, GO:0071230=IEA, GO:0030198=TAS, GO:0007411=TAS, GO:0030199=NAS, GO:0030574=TAS, GO:0007179=IDA, GO:0043206=IMP, GO:0034097=IDA, GO:0009314=IDA, GO:0001568=IEA, GO:0048407=IDA, GO:0030168=NAS, GO:0005576=TAS, GO:0048565=IEA, GO:0031012=IMP, GO:0001501=IEA, GO:0005178=IMP, GO:0018149=IDA, GO:0007160=IDA, GO:0050777=IMP, GO:0007229=IMP, GO:0042060=IDA, GO:0005788=TAS, GO:0043588=IMP, GO:0032964=IMP, GO:0005201=IMP} axon guidance, blood vessel development, cell-matrix adhesion, cellular response to amino acid stimulus, collagen biosynthetic process, collagen catabolic process, collagen fibril organization, digestive tract development, extracellular fibril organization, extracellular matrix disassembly, extracellular matrix organization, heart development, integrin-mediated signaling pathway, negative regulation of immune response, peptide cross-linking, platelet activation, response to cytokine stimulus, response to radiation, skeletal system development, skin development, transforming growth factor beta receptor signaling pathway, wound healing collagen, collagen type III, endoplasmic reticulum lumen, extracellular matrix, extracellular region, extracellular space SMAD binding, extracellular matrix structural constituent, integrin binding, metal ion binding, platelet-derived growth factor binding, protein binding Human COL4A1 BHF-UCL UniProtKB {GO:0005515=PMID:12011424, GO:0048407=PMID:8900172, GO:0005587=GO_REF:0000019, GO:0005576=Reactome:REACT_150470, GO:0001525=GO_REF:0000037, GO:0031012=PMID:22261194, GO:0071230=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0007528=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0005201=GO_REF:0000002} P02462 Collagen alpha-1(IV) chain protein 20120228 {GO:0005515=IPI, GO:0048407=IDA, GO:0005587=IEA, GO:0005576=TAS, GO:0001525=IEA, GO:0031012=ISS, GO:0071230=IEA, GO:0022617=TAS, GO:0007528=IEA, GO:0007411=TAS, GO:0030198=TAS, GO:0030574=TAS, GO:0005788=TAS, GO:0005201=IEA} angiogenesis, axon guidance, cellular response to amino acid stimulus, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, neuromuscular junction development collagen type IV, endoplasmic reticulum lumen, extracellular matrix, extracellular region extracellular matrix structural constituent, platelet-derived growth factor binding, protein binding colocalizes_with Human UniProtKB:F1KQQ4 COL4A2 BHF-UCL UniProtKB {GO:0005515=PMID:12011424, GO:0005587=PMID:2846280, GO:0071560=GO_REF:0000019, GO:0005576=Reactome:REACT_150470, GO:0001525=GO_REF:0000037, GO:0006351=GO_REF:0000019, GO:0031012=PMID:22261194, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0007411=Reactome:REACT_18266, GO:0016525=PMID:10625665, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0005201=PMID:8317999} P08572 Collagen alpha-2(IV) chain protein 20120228 {GO:0005515=IPI, GO:0005587=TAS, GO:0071560=IEA, GO:0005576=TAS, GO:0001525=IEA, GO:0006351=IEA, GO:0031012=ISS, GO:0022617=TAS, GO:0030198=TAS, GO:0007411=TAS, GO:0016525=IDA, GO:0030574=TAS, GO:0005788=TAS, GO:0005201=TAS} angiogenesis, axon guidance, cellular response to transforming growth factor beta stimulus, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, negative regulation of angiogenesis, transcription, DNA-dependent collagen type IV, endoplasmic reticulum lumen, extracellular matrix, extracellular region extracellular matrix structural constituent, protein binding colocalizes_with Human UniProtKB:F1RLL9 COL4A3 Reactome UniProtKB {GO:0005515=PMID:12682293, GO:0008285=PMID:10837460, GO:0006919=PMID:10766752, GO:0008283=PMID:10766752, GO:0008015=PMID:10766752, GO:0007605=PMID:7987396, GO:0005587=PMID:10766752, GO:0005576=Reactome:REACT_150470, GO:0006917=PMID:10766752, GO:0032836=GO_REF:0000024, GO:0005604=PMID:10766752, GO:0005178=PMID:10766752, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0007411=Reactome:REACT_18266, GO:0005198=PMID:3025878, GO:0008191=PMID:10766752, GO:0030574=Reactome:REACT_150401, GO:0016525=PMID:10766752, GO:0005788=Reactome:REACT_121366, GO:0007155=GO_REF:0000037, GO:0007166=PMID:10766752, GO:0005201=GO_REF:0000002} Q01955 Collagen alpha-3(IV) chain protein 20130301 {GO:0005515=IPI, GO:0008285=TAS, GO:0006919=IDA, GO:0008283=IDA, GO:0008015=TAS, GO:0007605=TAS, GO:0005587=IDA, GO:0005576=TAS, GO:0006917=IDA, GO:0032836=ISS, GO:0005604=IDA, GO:0005178=TAS, GO:0022617=TAS, GO:0030198=TAS, GO:0007411=TAS, GO:0005198=NAS, GO:0008191=NAS, GO:0030574=TAS, GO:0016525=IDA, GO:0005788=TAS, GO:0007155=IEA, GO:0007166=NAS, GO:0005201=IEA} activation of cysteine-type endopeptidase activity involved in apoptotic process, axon guidance, blood circulation, cell adhesion, cell proliferation, cell surface receptor signaling pathway, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, glomerular basement membrane development, induction of apoptosis, negative regulation of angiogenesis, negative regulation of cell proliferation, sensory perception of sound basement membrane, collagen type IV, endoplasmic reticulum lumen, extracellular region extracellular matrix structural constituent, integrin binding, metalloendopeptidase inhibitor activity, protein binding, structural molecule activity Human COL4A3BP HPA UniProtKB {GO:0005515=PMID:10212244, GO:0034976=GO_REF:0000019, GO:0048471=PMID:16895911, GO:0008283=GO_REF:0000019, GO:0006672=GO_REF:0000019, GO:0070273=PMID:14685229, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_19306, GO:0005739=GO_REF:0000019, GO:0006955=PMID:11007769, GO:0006936=GO_REF:0000019, GO:0006665=Reactome:REACT_19323, GO:0035621=PMID:18184806, GO:0035620=PMID:18184806, GO:0005794=GO_REF:0000052, GO:0030148=Reactome:REACT_115810, GO:0005730=GO_REF:0000052, GO:0055088=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0007165=GO_REF:0000019, GO:0000902=GO_REF:0000019, GO:0003007=GO_REF:0000019, GO:0004672=PMID:10212244, GO:0070584=GO_REF:0000019, GO:0097001=PMID:18184806, GO:0005789=Reactome:REACT_19306, GO:0006468=PMID:10212244, GO:0007029=GO_REF:0000019} Q9Y5P4 Collagen type IV alpha-3-binding protein protein 20110516 {GO:0005515=IPI, GO:0034976=IEA, GO:0048471=IDA, GO:0008283=IEA, GO:0006672=IEA, GO:0070273=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0005829=TAS, GO:0005739=IEA, GO:0006955=NAS, GO:0006936=IEA, GO:0006665=TAS, GO:0035621=IMP, GO:0035620=IDA, GO:0005794=IDA, GO:0030148=TAS, GO:0005730=IDA, GO:0055088=IEA, GO:0001701=IEA, GO:0007165=IEA, GO:0000902=IEA, GO:0003007=IEA, GO:0004672=TAS, GO:0070584=IEA, GO:0097001=IDA, GO:0005789=TAS, GO:0006468=TAS, GO:0007029=IEA} ER to Golgi ceramide transport, cell morphogenesis, cell proliferation, ceramide metabolic process, endoplasmic reticulum organization, heart morphogenesis, immune response, in utero embryonic development, lipid homeostasis, mitochondrion morphogenesis, muscle contraction, protein phosphorylation, response to endoplasmic reticulum stress, signal transduction, small molecule metabolic process, sphingolipid biosynthetic process, sphingolipid metabolic process Golgi apparatus, cytosol, endoplasmic reticulum membrane, mitochondrion, nucleolus, nucleus, perinuclear region of cytoplasm ceramide binding, ceramide transporter activity, phosphatidylinositol-4-phosphate binding, protein binding, protein kinase activity Human COL4A4 Reactome UniProtKB {GO:0005581=GO_REF:0000038, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0007411=Reactome:REACT_18266, GO:0030574=Reactome:REACT_150401, GO:0005605=PMID:2211832, GO:0005587=PMID:7523402, GO:0005788=Reactome:REACT_121366, GO:0005576=Reactome:REACT_150470, GO:0032836=PMID:17942953, GO:0005201=PMID:17942953} P53420 Collagen alpha-4(IV) chain protein 20130301 {GO:0005581=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0007411=TAS, GO:0030574=TAS, GO:0005605=IDA, GO:0005587=IDA, GO:0005788=TAS, GO:0005576=TAS, GO:0032836=IMP, GO:0005201=IMP} axon guidance, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, glomerular basement membrane development basal lamina, collagen, collagen type IV, endoplasmic reticulum lumen, extracellular region extracellular matrix structural constituent Human COL4A5 Reactome UniProtKB {GO:0005581=GO_REF:0000038, GO:0031594=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0007411=Reactome:REACT_18266, GO:0007528=GO_REF:0000019, GO:0030574=Reactome:REACT_150401, GO:0005605=GO_REF:0000019, GO:0005587=GO_REF:0000019, GO:0005788=Reactome:REACT_121366, GO:0005576=Reactome:REACT_150470, GO:0005201=GO_REF:0000002} P29400 Collagen alpha-5(IV) chain protein 20130301 {GO:0005581=IEA, GO:0031594=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0007411=TAS, GO:0007528=IEA, GO:0030574=TAS, GO:0005605=IEA, GO:0005587=IEA, GO:0005788=TAS, GO:0005576=TAS, GO:0005201=IEA} axon guidance, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, neuromuscular junction development basal lamina, collagen, collagen type IV, endoplasmic reticulum lumen, extracellular region, neuromuscular junction extracellular matrix structural constituent Human COL4A6 Reactome UniProtKB {GO:0005581=GO_REF:0000038, GO:0022617=Reactome:REACT_118572, GO:0071230=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0005587=PMID:8125972, GO:0005788=Reactome:REACT_121366, GO:0005576=Reactome:REACT_150470, GO:0007155=GO_REF:0000037, GO:0005201=GO_REF:0000029} Q14031 Collagen alpha-6(IV) chain protein 20130301 {GO:0005581=IEA, GO:0022617=TAS, GO:0071230=IEA, GO:0030198=TAS, GO:0030574=TAS, GO:0005587=NAS, GO:0005788=TAS, GO:0005576=TAS, GO:0007155=IEA, GO:0005201=NAS} cell adhesion, cellular response to amino acid stimulus, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization collagen, collagen type IV, endoplasmic reticulum lumen, extracellular region extracellular matrix structural constituent Human COL5A1 Reactome UniProtKB {GO:0005581=GO_REF:0000002, GO:0035313=PMID:18305566, GO:0048592=PMID:16431952, GO:0005588=PMID:9683580, GO:0046872=GO_REF:0000037, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0007411=Reactome:REACT_18266, GO:0030199=PMID:15095409, GO:0030574=Reactome:REACT_150401, GO:0045112=PMID:18305566, GO:0043206=PMID:14970208, GO:0007155=PMID:18305566, GO:0008201=PMID:2203476, GO:0001568=GO_REF:0000019, GO:0048407=PMID:8900172, GO:0043394=PMID:9099729, GO:0005576=Reactome:REACT_150374, GO:0005604=GO_REF:0000019, GO:0031012=PMID:14970208, GO:0003007=GO_REF:0000019, GO:0005178=PMID:14970208, GO:0016477=PMID:18305566, GO:0051128=GO_REF:0000019, GO:0005788=Reactome:REACT_121366, GO:0043588=PMID:9683580, GO:0032964=PMID:15095409, GO:0005201=GO_REF:0000019} P20908 Collagen alpha-1(V) chain protein 20130301 {GO:0005581=IEA, GO:0035313=IMP, GO:0048592=IMP, GO:0005588=IMP, GO:0046872=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0007411=TAS, GO:0030199=IMP, GO:0030574=TAS, GO:0045112=IMP, GO:0043206=IMP, GO:0007155=IMP, GO:0008201=IDA, GO:0001568=IEA, GO:0048407=IDA, GO:0043394=IPI, GO:0005576=TAS, GO:0005604=IEA, GO:0031012=IMP, GO:0003007=IEA, GO:0005178=NAS, GO:0016477=IMP, GO:0051128=IEA, GO:0005788=TAS, GO:0043588=IMP, GO:0032964=IMP, GO:0005201=IEA} axon guidance, blood vessel development, cell adhesion, cell migration, collagen biosynthetic process, collagen catabolic process, collagen fibril organization, extracellular fibril organization, extracellular matrix disassembly, extracellular matrix organization, eye morphogenesis, heart morphogenesis, integrin biosynthetic process, regulation of cellular component organization, skin development, wound healing, spreading of epidermal cells basement membrane, collagen, collagen type V, endoplasmic reticulum lumen, extracellular matrix, extracellular region extracellular matrix structural constituent, heparin binding, integrin binding, metal ion binding, platelet-derived growth factor binding, proteoglycan binding Human COL5A2 Reactome UniProtKB {GO:0046332=GO_REF:0000019, GO:0048592=PMID:16431952, GO:0005576=Reactome:REACT_150374, GO:0005588=PMID:9425231, GO:0046872=GO_REF:0000037, GO:0031012=PMID:17666000, GO:0003674=GO_REF:0000015, GO:0001501=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0071230=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0007411=Reactome:REACT_18266, GO:0030199=PMID:9425231, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0043588=PMID:9425231, GO:0005201=GO_REF:0000002} P05997 Collagen alpha-2(V) chain protein 20130301 {GO:0046332=IEA, GO:0048592=IMP, GO:0005576=TAS, GO:0005588=IMP, GO:0046872=IEA, GO:0031012=NAS, GO:0003674=ND, GO:0001501=IEA, GO:0022617=TAS, GO:0071230=IEA, GO:0030198=TAS, GO:0007411=TAS, GO:0030199=IMP, GO:0030574=TAS, GO:0005788=TAS, GO:0043588=IMP, GO:0005201=IEA} axon guidance, cellular response to amino acid stimulus, collagen catabolic process, collagen fibril organization, extracellular matrix disassembly, extracellular matrix organization, eye morphogenesis, skeletal system development, skin development collagen type V, endoplasmic reticulum lumen, extracellular matrix, extracellular region SMAD binding, extracellular matrix structural constituent, metal ion binding, molecular_function Human COL5A3 Reactome UniProtKB {GO:0005518=PMID:10722718, GO:0043394=GO_REF:0000019, GO:0005576=Reactome:REACT_150374, GO:0005588=PMID:10722718, GO:0007160=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0007411=Reactome:REACT_18266, GO:0030198=Reactome:REACT_118779, GO:0030199=PMID:10722718, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0043588=PMID:10722718, GO:0008201=GO_REF:0000019, GO:0005201=PMID:10722718} P25940 Collagen alpha-3(V) chain protein 20130301 {GO:0005518=NAS, GO:0043394=IEA, GO:0005576=TAS, GO:0005588=NAS, GO:0007160=IEA, GO:0022617=TAS, GO:0007411=TAS, GO:0030198=TAS, GO:0030199=NAS, GO:0030574=TAS, GO:0005788=TAS, GO:0043588=NAS, GO:0008201=IEA, GO:0005201=NAS} axon guidance, cell-matrix adhesion, collagen catabolic process, collagen fibril organization, extracellular matrix disassembly, extracellular matrix organization, skin development collagen type V, endoplasmic reticulum lumen, extracellular region collagen binding, extracellular matrix structural constituent, heparin binding, proteoglycan binding Human COL6A1 BHF-UCL UniProtKB {GO:0048407=PMID:8900172, GO:0005589=PMID:2551668, GO:0005576=Reactome:REACT_150311, GO:0031012=PMID:22261194, GO:0042383=GO_REF:0000019, GO:0070208=PMID:18400749, GO:0043234=PMID:18400749, GO:0071230=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0007411=Reactome:REACT_18266, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0007155=GO_REF:0000029} P12109 Collagen alpha-1(VI) chain protein 20120228 {GO:0048407=IDA, GO:0005589=NAS, GO:0005576=TAS, GO:0031012=ISS, GO:0042383=IEA, GO:0070208=IPI, GO:0043234=IPI, GO:0071230=IEA, GO:0022617=TAS, GO:0007411=TAS, GO:0030198=TAS, GO:0030574=TAS, GO:0005788=TAS, GO:0007155=NAS} axon guidance, cell adhesion, cellular response to amino acid stimulus, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, protein heterotrimerization collagen type VI, endoplasmic reticulum lumen, extracellular matrix, extracellular region, protein complex, sarcolemma platelet-derived growth factor binding colocalizes_with Human UniProtKB:Q1T7A8 COL6A2 BHF-UCL UniProtKB {GO:0005515=PMID:12812986, GO:0005581=GO_REF:0000037, GO:0005578=GO_REF:0000029, GO:0005576=Reactome:REACT_150311, GO:0031012=PMID:22261194, GO:0042383=GO_REF:0000019, GO:0070208=PMID:18400749, GO:0043234=PMID:18400749, GO:0016337=GO_REF:0000029, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0007411=Reactome:REACT_18266, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0030674=GO_REF:0000029, GO:0005201=GO_REF:0000029} P12110 Collagen alpha-2(VI) chain protein 20120228 {GO:0005515=IPI, GO:0005581=IEA, GO:0005578=NAS, GO:0005576=TAS, GO:0031012=ISS, GO:0042383=IEA, GO:0070208=IPI, GO:0043234=IPI, GO:0016337=NAS, GO:0022617=TAS, GO:0030198=TAS, GO:0007411=TAS, GO:0030574=TAS, GO:0005788=TAS, GO:0030674=NAS, GO:0005201=NAS} axon guidance, cell-cell adhesion, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, protein heterotrimerization collagen, endoplasmic reticulum lumen, extracellular matrix, extracellular region, protein complex, proteinaceous extracellular matrix, sarcolemma extracellular matrix structural constituent, protein binding, protein binding, bridging colocalizes_with Human UniProtKB:Q1T7A6 COL6A3 BHF-UCL UniProtKB {GO:0031012=PMID:22261194, GO:0042383=GO_REF:0000019, GO:0007517=PMID:8782832, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0007411=Reactome:REACT_18266, GO:0004867=GO_REF:0000037, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0005576=Reactome:REACT_150311, GO:0005589=PMID:8782832, GO:0007155=GO_REF:0000037} P12111 Collagen alpha-3(VI) chain protein 20120228 {GO:0031012=ISS, GO:0042383=IEA, GO:0007517=TAS, GO:0022617=TAS, GO:0030198=TAS, GO:0007411=TAS, GO:0004867=IEA, GO:0030574=TAS, GO:0005788=TAS, GO:0005576=TAS, GO:0005589=TAS, GO:0007155=IEA} axon guidance, cell adhesion, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, muscle organ development collagen type VI, endoplasmic reticulum lumen, extracellular matrix, extracellular region, sarcolemma serine-type endopeptidase inhibitor activity colocalizes_with Human UniProtKB:Q1T7A5 COL6A5 BHF-UCL UniProtKB {GO:0031012=PMID:22261194, GO:0005581=GO_REF:0000037, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0005576=Reactome:REACT_150235, GO:0007155=GO_REF:0000037} A8TX70 Collagen alpha-5(VI) chain protein 20120228 {GO:0031012=ISS, GO:0005581=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0030574=TAS, GO:0005576=TAS, GO:0007155=IEA} cell adhesion, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization collagen, extracellular matrix, extracellular region colocalizes_with Human UniProtKB:F1RS99 COL7A1 BHF-UCL UniProtKB {GO:0031012=PMID:22261194, GO:0005515=PMID:19269366, GO:0022617=Reactome:REACT_118572, GO:0008544=PMID:8170945, GO:0030198=Reactome:REACT_118779, GO:0004867=GO_REF:0000037, GO:0005590=PMID:9375848, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0005576=Reactome:REACT_150470, GO:0007155=GO_REF:0000037, GO:0005604=GO_REF:0000039} Q02388 Collagen alpha-1(VII) chain protein 20120228 {GO:0031012=ISS, GO:0005515=IPI, GO:0022617=TAS, GO:0008544=TAS, GO:0030198=TAS, GO:0004867=IEA, GO:0005590=TAS, GO:0030574=TAS, GO:0005788=TAS, GO:0005576=TAS, GO:0007155=IEA, GO:0005604=IEA} cell adhesion, collagen catabolic process, epidermis development, extracellular matrix disassembly, extracellular matrix organization basement membrane, collagen type VII, endoplasmic reticulum lumen, extracellular matrix, extracellular region protein binding, serine-type endopeptidase inhibitor activity colocalizes_with Human UniProtKB:F1SKM1 COL8A1 Reactome UniProtKB {GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0005591=PMID:2029894, GO:0030574=Reactome:REACT_150401, GO:0010811=GO_REF:0000019, GO:0005788=Reactome:REACT_121366, GO:0005576=Reactome:REACT_150344, GO:0001525=GO_REF:0000037, GO:0048593=GO_REF:0000019, GO:0007155=GO_REF:0000037, GO:0050673=GO_REF:0000019, GO:0005604=GO_REF:0000039} P27658 Collagen alpha-1(VIII) chain protein 20130301 {GO:0022617=TAS, GO:0030198=TAS, GO:0005591=TAS, GO:0030574=TAS, GO:0010811=IEA, GO:0005788=TAS, GO:0005576=TAS, GO:0001525=IEA, GO:0048593=IEA, GO:0007155=IEA, GO:0050673=IEA, GO:0005604=IEA} angiogenesis, camera-type eye morphogenesis, cell adhesion, collagen catabolic process, epithelial cell proliferation, extracellular matrix disassembly, extracellular matrix organization, positive regulation of cell-substrate adhesion basement membrane, collagen type VIII, endoplasmic reticulum lumen, extracellular region Human COL8A2 Reactome UniProtKB {GO:0005581=GO_REF:0000037, GO:0005578=PMID:2019595, GO:0005576=Reactome:REACT_150344, GO:0048593=GO_REF:0000019, GO:0001525=GO_REF:0000037, GO:0050673=GO_REF:0000019, GO:0005604=PMID:2019595, GO:0016337=PMID:2019595, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0030674=PMID:2019595, GO:0005201=PMID:2019595} P25067 Collagen alpha-2(VIII) chain protein 20130301 {GO:0005581=IEA, GO:0005578=NAS, GO:0005576=TAS, GO:0048593=IEA, GO:0001525=IEA, GO:0050673=IEA, GO:0005604=NAS, GO:0016337=NAS, GO:0022617=TAS, GO:0030198=TAS, GO:0030574=TAS, GO:0005788=TAS, GO:0030674=NAS, GO:0005201=NAS} angiogenesis, camera-type eye morphogenesis, cell-cell adhesion, collagen catabolic process, epithelial cell proliferation, extracellular matrix disassembly, extracellular matrix organization basement membrane, collagen, endoplasmic reticulum lumen, extracellular region, proteinaceous extracellular matrix extracellular matrix structural constituent, protein binding, bridging Human COL9A1 BHF-UCL UniProtKB {GO:0003417=GO_REF:0000019, GO:0030020=PMID:8660302, GO:0022617=Reactome:REACT_118572, GO:0001894=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0007411=Reactome:REACT_18266, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0009887=PMID:3473493, GO:0005576=Reactome:REACT_18390, GO:0005594=PMID:8660302, GO:0046872=GO_REF:0000037} P20849 Collagen alpha-1(IX) chain protein 20080919 {GO:0003417=IEA, GO:0030020=IC, GO:0022617=TAS, GO:0001894=IEA, GO:0030198=TAS, GO:0007411=TAS, GO:0030574=TAS, GO:0005788=TAS, GO:0009887=TAS, GO:0005576=TAS, GO:0005594=IDA, GO:0046872=IEA} axon guidance, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, growth plate cartilage development, organ morphogenesis, tissue homeostasis collagen type IX, endoplasmic reticulum lumen, extracellular region extracellular matrix structural constituent conferring tensile strength, metal ion binding Human COL9A2 BHF-UCL UniProtKB {GO:0001501=PMID:10364514, GO:0030020=PMID:8660302, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0007411=Reactome:REACT_18266, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0005594=PMID:8660302, GO:0005576=Reactome:REACT_121366} Q14055 Collagen alpha-2(IX) chain protein 20080919 {GO:0001501=TAS, GO:0030020=IC, GO:0022617=TAS, GO:0030198=TAS, GO:0007411=TAS, GO:0030574=TAS, GO:0005788=TAS, GO:0005594=IDA, GO:0005576=TAS} axon guidance, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, skeletal system development collagen type IX, endoplasmic reticulum lumen, extracellular region extracellular matrix structural constituent conferring tensile strength Human GO:0005594 COL9A3 BHF-UCL UniProtKB {GO:0008585=GO_REF:0000019, GO:0030020=PMID:8660302, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0007411=Reactome:REACT_18266, GO:0030574=Reactome:REACT_150401, GO:0005788=Reactome:REACT_121366, GO:0005594=PMID:8660302, GO:0005576=Reactome:REACT_121366, GO:0008584=GO_REF:0000019} Q14050 Collagen alpha-3(IX) chain protein 20080919 {GO:0008585=IEA, GO:0030020=IC, GO:0022617=TAS, GO:0030198=TAS, GO:0007411=TAS, GO:0030574=TAS, GO:0005788=TAS, GO:0005594=IDA, GO:0005576=TAS, GO:0008584=IEA} axon guidance, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, female gonad development, male gonad development collagen type IX, endoplasmic reticulum lumen, extracellular region extracellular matrix structural constituent conferring tensile strength Human GO:0005594 COLEC12 GOC UniProtKB {GO:0005581=GO_REF:0000037, GO:0030169=PMID:11564734, GO:0006952=PMID:11162630, GO:0006910=PMID:11564734, GO:0046872=GO_REF:0000037, GO:0009756=PMID:11564734, GO:0002221=PMID:11564734, GO:0005534=PMID:11564734, GO:0045087=PMID:11564734, GO:0051260=PMID:11564734, GO:0016021=PMID:11162630, GO:0005044=PMID:11162630, GO:0008329=PMID:11564734} Q5KU26 Collectin-12 protein 20130413 {GO:0005581=IEA, GO:0030169=IDA, GO:0006952=TAS, GO:0006910=IDA, GO:0046872=IEA, GO:0009756=NAS, GO:0002221=IDA, GO:0005534=NAS, GO:0045087=TAS, GO:0051260=NAS, GO:0016021=TAS, GO:0005044=TAS, GO:0008329=IDA} carbohydrate mediated signaling, defense response, innate immune response, pattern recognition receptor signaling pathway, phagocytosis, recognition, protein homooligomerization collagen, integral to membrane galactose binding, low-density lipoprotein particle binding, metal ion binding, pattern recognition receptor activity, scavenger receptor activity Human COLQ IntAct UniProtKB {GO:0005515=PMID:15526038, GO:0005581=GO_REF:0000037, GO:0030054=GO_REF:0000037, GO:0008105=PMID:9689136, GO:0005605=PMID:9689136, GO:0001507=PMID:9689136, GO:0045202=GO_REF:0000039, GO:0005615=PMID:9689136} Q9Y215 Acetylcholinesterase collagenic tail peptide protein 20130415 {GO:0005515=IPI, GO:0005581=IEA, GO:0030054=IEA, GO:0008105=TAS, GO:0005605=TAS, GO:0001507=TAS, GO:0045202=IEA, GO:0005615=TAS} acetylcholine catabolic process in synaptic cleft, asymmetric protein localization basal lamina, cell junction, collagen, extracellular space, synapse protein binding Human UniProtKB:P22303 COMMD1 HPA UniProtKB {GO:0005515=PMID:15799966, GO:0030054=GO_REF:0000052, GO:0055070=PMID:14685266, GO:0005507=PMID:17309234, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0032434=PMID:17183367, GO:0032088=PMID:16573520, GO:0042803=PMID:15799966, GO:0042802=PMID:15799966, GO:0005737=GO_REF:0000052, GO:0031398=PMID:17183367, GO:0031462=PMID:17183367} Q8N668 COMM domain-containing protein 1 protein 20101115 {GO:0005515=IPI, GO:0030054=IDA, GO:0055070=IDA, GO:0005507=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0032434=IMP, GO:0032088=IDA, GO:0042803=IPI, GO:0042802=IPI, GO:0005737=IDA, GO:0031398=IDA, GO:0031462=IDA} copper ion homeostasis, negative regulation of NF-kappaB transcription factor activity, positive regulation of protein ubiquitination, regulation of proteasomal ubiquitin-dependent protein catabolic process Cul2-RING ubiquitin ligase complex, cell junction, cytoplasm, nucleolus, nucleus copper ion binding, identical protein binding, protein binding, protein homodimerization activity Human COMMD10 UniProtKB UniProtKB {GO:0005515=PMID:15799966} Q9Y6G5 COMM domain-containing protein 10 protein 20101213 {GO:0005515=IPI} protein binding Human UniProtKB:Q8N668 COMMD2 UniProtKB UniProtKB {GO:0005515=PMID:15799966} Q86X83 COMM domain-containing protein 2 protein 20101213 {GO:0005515=IPI} protein binding Human UniProtKB:Q8N668 COMMD3 IntAct UniProtKB {GO:0005515=PMID:15799966} Q9UBI1 COMM domain-containing protein 3 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:Q8N668 COMMD4 IntAct UniProtKB {GO:0005515=PMID:15799966, GO:0005737=GO_REF:0000054} Q9H0A8 COMM domain-containing protein 4 protein 20130415 {GO:0005515=IPI, GO:0005737=IDA} cytoplasm protein binding Human UniProtKB:Q8N668 COMMD5 UniProtKB UniProtKB {GO:0005515=PMID:15799966, GO:0005634=GO_REF:0000039} Q9GZQ3 COMM domain-containing protein 5 protein 20101213 {GO:0005515=IPI, GO:0005634=IEA} nucleus protein binding Human UniProtKB:Q8N668 COMMD6 IntAct UniProtKB {GO:0005515=PMID:15799966, GO:0005737=GO_REF:0000039, GO:0051059=PMID:16573520, GO:0032088=PMID:16573520, GO:0005634=GO_REF:0000039} Q7Z4G1 COMM domain-containing protein 6 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0051059=IPI, GO:0032088=IDA, GO:0005634=IEA} negative regulation of NF-kappaB transcription factor activity cytoplasm, nucleus NF-kappaB binding, protein binding Human UniProtKB:Q8N668 COMMD7 UniProtKB UniProtKB {GO:0005515=PMID:15799966, GO:0051059=PMID:15799966, GO:0032088=PMID:15799966, GO:0005575=GO_REF:0000015, GO:0045892=PMID:15799966, GO:0033209=PMID:15799966} Q86VX2 COMM domain-containing protein 7 protein 20101213 {GO:0005515=IPI, GO:0051059=IDA, GO:0032088=IDA, GO:0005575=ND, GO:0045892=IDA, GO:0033209=IDA} negative regulation of NF-kappaB transcription factor activity, negative regulation of transcription, DNA-dependent, tumor necrosis factor-mediated signaling pathway cellular_component NF-kappaB binding, protein binding Human UniProtKB:Q8N668 COMMD8 UniProtKB UniProtKB {GO:0005515=PMID:15799966} Q9NX08 COMM domain-containing protein 8 protein 20101213 {GO:0005515=IPI} protein binding Human UniProtKB:Q8N668 COMMD9 null null {} null null null null {} null null null COMP UniProtKB UniProtKB {GO:0005515=PMID:16051604, GO:0003417=GO_REF:0000019, GO:0043066=PMID:17993464, GO:0005509=PMID:11084047, GO:0005518=PMID:11084047, GO:0005578=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0005576=GO_REF:0000002, GO:0043395=PMID:17588949, GO:0001501=PMID:7670472, GO:0009887=PMID:7713493, GO:0060173=PMID:16542502, GO:0007155=GO_REF:0000037, GO:0008201=PMID:17588949, GO:0005201=PMID:7713493} P49747 Cartilage oligomeric matrix protein protein 20090909 {GO:0005515=IPI, GO:0003417=IEA, GO:0043066=IDA, GO:0005509=IDA, GO:0005518=IDA, GO:0005578=IEA, GO:0006915=IEA, GO:0005576=IEA, GO:0043395=IDA, GO:0001501=TAS, GO:0009887=TAS, GO:0060173=IDA, GO:0007155=IEA, GO:0008201=IDA, GO:0005201=TAS} apoptotic process, cell adhesion, growth plate cartilage development, limb development, negative regulation of apoptotic process, organ morphogenesis, skeletal system development extracellular region, proteinaceous extracellular matrix calcium ion binding, collagen binding, extracellular matrix structural constituent, heparan sulfate proteoglycan binding, heparin binding, protein binding Human UniProtKB:P08648 COMT HPA UniProtKB {GO:0014070=GO_REF:0000019, GO:0006805=Reactome:REACT_13433, GO:0005886=Reactome:REACT_15553, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0032259=Reactome:REACT_6946, GO:0043231=GO_REF:0000052, GO:0050668=GO_REF:0000019, GO:0005829=Reactome:REACT_6885, GO:0005739=GO_REF:0000019, GO:0048609=GO_REF:0000019, GO:0045963=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0007612=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:0000287=GO_REF:0000002, GO:0042493=GO_REF:0000019, GO:0016206=GO_REF:0000003, GO:0048662=GO_REF:0000019, GO:0008171=PMID:1707278, GO:0008210=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0006584=GO_REF:0000002, GO:0042420=GO_REF:0000019, GO:0048265=GO_REF:0000019, GO:0042136=Reactome:REACT_13583, GO:0016021=GO_REF:0000037, GO:0042135=GO_REF:0000037} P21964 Catechol O-methyltransferase protein 20101115 {GO:0014070=IEA, GO:0006805=TAS, GO:0005886=TAS, GO:0007268=TAS, GO:0044281=TAS, GO:0032259=TAS, GO:0043231=IDA, GO:0050668=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0048609=IEA, GO:0045963=IEA, GO:0032496=IEA, GO:0007612=IEA, GO:0007565=IEA, GO:0000287=IEA, GO:0042493=IEA, GO:0016206=IEA, GO:0048662=IEA, GO:0008171=TAS, GO:0008210=IEA, GO:0016020=IEA, GO:0006584=IEA, GO:0042420=IEA, GO:0048265=IEA, GO:0042136=TAS, GO:0016021=IEA, GO:0042135=IEA} catecholamine metabolic process, dopamine catabolic process, estrogen metabolic process, female pregnancy, learning, methylation, multicellular organismal reproductive process, negative regulation of dopamine metabolic process, negative regulation of smooth muscle cell proliferation, neurotransmitter biosynthetic process, neurotransmitter catabolic process, positive regulation of homocysteine metabolic process, response to drug, response to lipopolysaccharide, response to organic cyclic compound, response to pain, small molecule metabolic process, synaptic transmission, xenobiotic metabolic process cytosol, integral to membrane, intracellular membrane-bounded organelle, membrane, mitochondrion, plasma membrane O-methyltransferase activity, catechol O-methyltransferase activity, magnesium ion binding Human COMTD1 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0008171=GO_REF:0000002} Q86VU5 Catechol O-methyltransferase domain-containing protein 1 protein 20130413 {GO:0005739=IEA, GO:0016021=IEA, GO:0008171=IEA} integral to membrane, mitochondrion O-methyltransferase activity Human Ensembl:ENSMUSP00000119330 COPA Reactome UniProtKB {GO:0005737=PMID:9115636, GO:0030126=PMID:14729954, GO:0005179=GO_REF:0000037, GO:0005198=GO_REF:0000002, GO:0006890=Reactome:REACT_11208, GO:0030157=PMID:1429581, GO:0005615=PMID:1429581, GO:0006886=GO_REF:0000002, GO:0048205=Reactome:REACT_11096, GO:0016044=Reactome:REACT_11123, GO:0005829=Reactome:REACT_11243} P53621 Coatomer subunit alpha protein 20130213 {GO:0005737=IDA, GO:0030126=IDA, GO:0005179=IEA, GO:0005198=IEA, GO:0006890=TAS, GO:0030157=IDA, GO:0005615=IDA, GO:0006886=IEA, GO:0048205=TAS, GO:0016044=TAS, GO:0005829=TAS} COPI coating of Golgi vesicle, cellular membrane organization, intracellular protein transport, pancreatic juice secretion, retrograde vesicle-mediated transport, Golgi to ER COPI vesicle coat, cytoplasm, cytosol, extracellular space hormone activity, structural molecule activity Human COPB1 Reactome UniProtKB {GO:0005515=PMID:18556652, GO:0030126=GO_REF:0000024, GO:0005793=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0006890=Reactome:REACT_11208, GO:0005798=PMID:1840503, GO:0006891=GO_REF:0000024, GO:0006886=GO_REF:0000002, GO:0048205=Reactome:REACT_11096, GO:0030117=GO_REF:0000002, GO:0005829=Reactome:REACT_11243, GO:0000139=PMID:1840503, GO:0005198=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0016192=GO_REF:0000002, GO:0016044=Reactome:REACT_11123} P53618 Coatomer subunit beta protein 20130213 {GO:0005515=IPI, GO:0030126=ISS, GO:0005793=IEA, GO:0005886=IEA, GO:0006890=TAS, GO:0005798=TAS, GO:0006891=ISS, GO:0006886=IEA, GO:0048205=TAS, GO:0030117=IEA, GO:0005829=TAS, GO:0000139=TAS, GO:0005198=IEA, GO:0019048=IEA, GO:0016192=IEA, GO:0016044=TAS} COPI coating of Golgi vesicle, cellular membrane organization, intra-Golgi vesicle-mediated transport, intracellular protein transport, retrograde vesicle-mediated transport, Golgi to ER, vesicle-mediated transport, virus-host interaction COPI vesicle coat, Golgi membrane, Golgi-associated vesicle, cytosol, endoplasmic reticulum-Golgi intermediate compartment, membrane coat, plasma membrane protein binding, structural molecule activity Human COPB2 HPA UniProtKB {GO:0030126=PMID:14729954, GO:0005794=GO_REF:0000052, GO:0006890=Reactome:REACT_11208, GO:0006891=PMID:8335000, GO:0015629=GO_REF:0000052, GO:0006886=GO_REF:0000002, GO:0030117=GO_REF:0000002, GO:0048205=Reactome:REACT_11096, GO:0005829=Reactome:REACT_11243, GO:0005737=GO_REF:0000052, GO:0005198=GO_REF:0000002, GO:0016192=GO_REF:0000002, GO:0016044=Reactome:REACT_11123} P35606 Coatomer subunit beta' protein 20110516 {GO:0030126=IDA, GO:0005794=IDA, GO:0006890=TAS, GO:0006891=IDA, GO:0015629=IDA, GO:0006886=IEA, GO:0030117=IEA, GO:0048205=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0005198=IEA, GO:0016192=IEA, GO:0016044=TAS} COPI coating of Golgi vesicle, cellular membrane organization, intra-Golgi vesicle-mediated transport, intracellular protein transport, retrograde vesicle-mediated transport, Golgi to ER, vesicle-mediated transport COPI vesicle coat, Golgi apparatus, actin cytoskeleton, cytoplasm, cytosol, membrane coat structural molecule activity Human COPE LIFEdb UniProtKB {GO:0030126=GO_REF:0000024, GO:0005794=GO_REF:0000054, GO:0005198=GO_REF:0000002, GO:0006890=Reactome:REACT_11208, GO:0006891=GO_REF:0000024, GO:0015031=GO_REF:0000037, GO:0048205=Reactome:REACT_11096, GO:0016044=Reactome:REACT_11123, GO:0005829=Reactome:REACT_11243} O14579 Coatomer subunit epsilon protein 20100607 {GO:0030126=ISS, GO:0005794=IDA, GO:0005198=IEA, GO:0006890=TAS, GO:0006891=ISS, GO:0015031=IEA, GO:0048205=TAS, GO:0016044=TAS, GO:0005829=TAS} COPI coating of Golgi vesicle, cellular membrane organization, intra-Golgi vesicle-mediated transport, protein transport, retrograde vesicle-mediated transport, Golgi to ER COPI vesicle coat, Golgi apparatus, cytosol structural molecule activity Human COPG2 MGI UniProtKB {GO:0030126=PMID:1472999, GO:0005198=GO_REF:0000002, GO:0006890=PMID:11030615, GO:0006891=PMID:11056392, GO:0016192=GO_REF:0000002, GO:0006886=GO_REF:0000002, GO:0030117=GO_REF:0000002} Q9UBF2 Coatomer subunit gamma-2 protein 20060111 {GO:0030126=IDA, GO:0005198=IEA, GO:0006890=TAS, GO:0006891=IDA, GO:0016192=IEA, GO:0006886=IEA, GO:0030117=IEA} intra-Golgi vesicle-mediated transport, intracellular protein transport, retrograde vesicle-mediated transport, Golgi to ER, vesicle-mediated transport COPI vesicle coat, membrane coat structural molecule activity Human COPS2 UniProtKB UniProtKB {GO:0005515=PMID:17438371, GO:0007165=PMID:9535219, GO:0005737=PMID:9535219, GO:0008180=PMID:18850735, GO:0006366=PMID:7776974, GO:0008283=GO_REF:0000019, GO:0030182=GO_REF:0000019, GO:0003714=GO_REF:0000019, GO:0010388=PMID:19141280, GO:0004871=PMID:9535219, GO:0000122=GO_REF:0000019} P61201 COP9 signalosome complex subunit 2 protein 20110518 {GO:0005515=IPI, GO:0007165=NAS, GO:0005737=IDA, GO:0008180=IDA, GO:0006366=TAS, GO:0008283=IEA, GO:0030182=IEA, GO:0003714=IEA, GO:0010388=IDA, GO:0004871=NAS, GO:0000122=IEA} cell proliferation, cullin deneddylation, negative regulation of transcription from RNA polymerase II promoter, neuron differentiation, signal transduction, transcription from RNA polymerase II promoter cytoplasm, signalosome protein binding, signal transducer activity, transcription corepressor activity Human COPS3 HPA UniProtKB {GO:0005515=PMID:12620389, GO:0007165=PMID:9535219, GO:0005737=GO_REF:0000052, GO:0008180=PMID:18850735, GO:0010388=PMID:19141280, GO:0005634=GO_REF:0000052, GO:0009416=PMID:9535219, GO:0001701=GO_REF:0000019} Q9UNS2 COP9 signalosome complex subunit 3 protein 20100326 {GO:0005515=IPI, GO:0007165=TAS, GO:0005737=IDA, GO:0008180=IDA, GO:0010388=IDA, GO:0005634=IDA, GO:0009416=TAS, GO:0001701=IEA} cullin deneddylation, in utero embryonic development, response to light stimulus, signal transduction cytoplasm, nucleus, signalosome protein binding Human COPS4 HPA UniProtKB {GO:0005515=PMID:20195357, GO:0005737=GO_REF:0000039, GO:0008180=PMID:18850735, GO:0010388=PMID:19141280, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9BT78 COP9 signalosome complex subunit 4 protein 20120912 {GO:0005515=IPI, GO:0005737=IEA, GO:0008180=IDA, GO:0010388=IDA, GO:0005730=IDA, GO:0005634=IDA} cullin deneddylation cytoplasm, nucleolus, nucleus, signalosome protein binding NOT Human COPS5 GOC UniProtKB {GO:0005515=PMID:21499297, GO:0000338=PMID:19214193, GO:0048471=GO_REF:0000039, GO:0005852=PMID:9341143, GO:0006366=PMID:8837781, GO:0003713=PMID:8837781, GO:0010388=PMID:19141280, GO:0005730=GO_REF:0000052, GO:0003743=PMID:9341143, GO:0005634=GO_REF:0000052, GO:0006412=PMID:9341143, GO:0006413=PMID:9341143, GO:0046872=GO_REF:0000037, GO:0046328=PMID:16410250, GO:0005737=PMID:17050680, GO:0008180=PMID:18850735, GO:0045944=PMID:16410250, GO:0051726=GO_REF:0000019, GO:0006508=GO_REF:0000037, GO:0008237=PMID:19214193} Q92905 COP9 signalosome complex subunit 5 protein 20130413 {GO:0005515=IPI, GO:0000338=IMP, GO:0048471=IEA, GO:0005852=TAS, GO:0006366=TAS, GO:0003713=TAS, GO:0010388=IDA, GO:0005730=IDA, GO:0003743=TAS, GO:0005634=IDA, GO:0006412=TAS, GO:0006413=TAS, GO:0046872=IEA, GO:0046328=IDA, GO:0005737=IDA, GO:0008180=IDA, GO:0045944=IDA, GO:0051726=IEA, GO:0006508=IEA, GO:0008237=IMP} cullin deneddylation, positive regulation of transcription from RNA polymerase II promoter, protein deneddylation, proteolysis, regulation of JNK cascade, regulation of cell cycle, transcription from RNA polymerase II promoter, translation, translational initiation cytoplasm, eukaryotic translation initiation factor 3 complex, nucleolus, nucleus, perinuclear region of cytoplasm, signalosome metal ion binding, metallopeptidase activity, protein binding, transcription coactivator activity, translation initiation factor activity Human COPS6 HPA UniProtKB {GO:0005515=PMID:21625211, GO:0005737=GO_REF:0000039, GO:0008180=PMID:18850735, GO:0019048=GO_REF:0000037, GO:0010388=PMID:19141280, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q7L5N1 COP9 signalosome complex subunit 6 protein 20111111 {GO:0005515=IPI, GO:0005737=IEA, GO:0008180=IDA, GO:0019048=IEA, GO:0010388=IDA, GO:0005730=IDA, GO:0005634=IDA} cullin deneddylation, virus-host interaction cytoplasm, nucleolus, nucleus, signalosome protein binding NOT Human COPS7A HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0008180=PMID:18850735, GO:0010388=PMID:19141280, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9UBW8 COP9 signalosome complex subunit 7a protein 20101115 {GO:0005737=IDA, GO:0008180=IDA, GO:0010388=IDA, GO:0005730=IDA, GO:0005634=IDA} cullin deneddylation cytoplasm, nucleolus, nucleus, signalosome Human COPS7B HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0008180=PMID:18850735, GO:0010388=PMID:19141280} Q9H9Q2 COP9 signalosome complex subunit 7b protein 20110516 {GO:0005737=IDA, GO:0008180=IDA, GO:0010388=IDA} cullin deneddylation cytoplasm, signalosome Human COPS8 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0008180=PMID:18850735, GO:0010388=PMID:19141280, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q99627 COP9 signalosome complex subunit 8 protein 20110516 {GO:0005737=IDA, GO:0008180=IDA, GO:0010388=IDA, GO:0005730=IDA, GO:0005634=IDA} cullin deneddylation cytoplasm, nucleolus, nucleus, signalosome Human COPZ1 Reactome UniProtKB {GO:0030126=PMID:14729954, GO:0006890=Reactome:REACT_11208, GO:0006810=GO_REF:0000002, GO:0006891=GO_REF:0000024, GO:0016192=GO_REF:0000002, GO:0006886=GO_REF:0000002, GO:0048205=Reactome:REACT_11096, GO:0016044=Reactome:REACT_11123, GO:0030117=GO_REF:0000002, GO:0005829=Reactome:REACT_11243} P61923 Coatomer subunit zeta-1 protein 20130213 {GO:0030126=IDA, GO:0006890=TAS, GO:0006810=IEA, GO:0006891=ISS, GO:0016192=IEA, GO:0006886=IEA, GO:0048205=TAS, GO:0016044=TAS, GO:0030117=IEA, GO:0005829=TAS} COPI coating of Golgi vesicle, cellular membrane organization, intra-Golgi vesicle-mediated transport, intracellular protein transport, retrograde vesicle-mediated transport, Golgi to ER, transport, vesicle-mediated transport COPI vesicle coat, cytosol, membrane coat Human COPZ2 MGI UniProtKB {GO:0005801=PMID:11056392, GO:0030126=PMID:14729954, GO:0006810=GO_REF:0000002, GO:0016192=GO_REF:0000037, GO:0006886=PMID:11056392} Q9P299 Coatomer subunit zeta-2 protein 20060111 {GO:0005801=NAS, GO:0030126=IDA, GO:0006810=IEA, GO:0016192=IEA, GO:0006886=NAS} intracellular protein transport, transport, vesicle-mediated transport COPI vesicle coat, cis-Golgi network Human COQ10A UniProtKB UniProtKB {GO:0005743=GO_REF:0000039} Q96MF6 Coenzyme Q-binding protein COQ10 homolog A, mitochondrial protein 20130413 {GO:0005743=IEA} mitochondrial inner membrane Human UniProtKB-SubCell:SL-0168 COQ10B UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0005743=GO_REF:0000039} Q9H8M1 Coenzyme Q-binding protein COQ10 homolog B, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0005743=IEA} mitochondrial inner membrane, mitochondrion Human UniProtKB-SubCell:SL-0168 COQ2 Reactome UniProtKB {GO:0005739=PMID:15153069, GO:0006744=Reactome:REACT_160111, GO:0047293=GO_REF:0000003, GO:0005743=Reactome:REACT_160153, GO:0044281=Reactome:REACT_111217, GO:0016021=PMID:15153069, GO:0008299=GO_REF:0000037, GO:0006071=PMID:15153069, GO:0002083=GO_REF:0000003, GO:0004659=GO_REF:0000002} Q96H96 4-hydroxybenzoate polyprenyltransferase, mitochondrial protein 20130301 {GO:0005739=RCA, GO:0006744=TAS, GO:0047293=IEA, GO:0005743=TAS, GO:0044281=TAS, GO:0016021=RCA, GO:0008299=IEA, GO:0006071=IGI, GO:0002083=IEA, GO:0004659=IEA} glycerol metabolic process, isoprenoid biosynthetic process, small molecule metabolic process, ubiquinone biosynthetic process integral to membrane, mitochondrial inner membrane, mitochondrion 4-hydroxybenzoate decaprenyltransferase activity, 4-hydroxybenzoate nonaprenyltransferase activity, prenyltransferase activity Human COQ4 LIFEdb UniProtKB {GO:0005739=GO_REF:0000054, GO:0006744=GO_REF:0000041, GO:0005743=GO_REF:0000039} Q9Y3A0 Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial protein 20100607 {GO:0005739=IDA, GO:0006744=IEA, GO:0005743=IEA} ubiquinone biosynthetic process mitochondrial inner membrane, mitochondrion Human COQ5 Reactome UniProtKB {GO:0005739=GO_REF:0000039, GO:0006744=Reactome:REACT_160111, GO:0008168=GO_REF:0000037, GO:0044281=Reactome:REACT_111217} Q5HYK3 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial protein 20130301 {GO:0005739=IEA, GO:0006744=TAS, GO:0008168=IEA, GO:0044281=TAS} small molecule metabolic process, ubiquinone biosynthetic process mitochondrion methyltransferase activity Human COQ6 LIFEdb UniProtKB {GO:0005739=GO_REF:0000054, GO:0006744=Reactome:REACT_160111, GO:0005794=GO_REF:0000039, GO:0050660=GO_REF:0000002, GO:0016709=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0042995=GO_REF:0000039} Q9Y2Z9 Ubiquinone biosynthesis monooxygenase COQ6 protein 20100607 {GO:0005739=IDA, GO:0006744=TAS, GO:0005794=IEA, GO:0050660=IEA, GO:0016709=IEA, GO:0044281=TAS, GO:0042995=IEA} small molecule metabolic process, ubiquinone biosynthetic process Golgi apparatus, cell projection, mitochondrion flavin adenine dinucleotide binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen Human COQ7 Reactome UniProtKB {GO:0005743=GO_REF:0000039, GO:0046914=GO_REF:0000002, GO:0005634=GO_REF:0000054, GO:0044281=Reactome:REACT_111217, GO:0001701=GO_REF:0000019, GO:0008340=GO_REF:0000019, GO:0001841=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0006744=Reactome:REACT_160111, GO:0070584=GO_REF:0000019, GO:0042775=GO_REF:0000019, GO:0016491=GO_REF:0000002, GO:0034599=GO_REF:0000019, GO:0001306=GO_REF:0000019, GO:0055114=GO_REF:0000002, GO:0022008=GO_REF:0000019} Q99807 Ubiquinone biosynthesis protein COQ7 homolog protein 20120315 {GO:0005743=IEA, GO:0046914=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0001701=IEA, GO:0008340=IEA, GO:0001841=IEA, GO:0005739=IEA, GO:0006744=TAS, GO:0070584=IEA, GO:0042775=IEA, GO:0016491=IEA, GO:0034599=IEA, GO:0001306=IEA, GO:0055114=IEA, GO:0022008=IEA} age-dependent response to oxidative stress, cellular response to oxidative stress, determination of adult lifespan, in utero embryonic development, mitochondrial ATP synthesis coupled electron transport, mitochondrion morphogenesis, neural tube formation, neurogenesis, oxidation-reduction process, small molecule metabolic process, ubiquinone biosynthetic process mitochondrial inner membrane, mitochondrion, nucleus oxidoreductase activity, transition metal ion binding Human COQ9 UniPathway UniProtKB {GO:0005739=GO_REF:0000039, GO:0006744=GO_REF:0000041} O75208 Ubiquinone biosynthesis protein COQ9, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0006744=IEA} ubiquinone biosynthetic process mitochondrion Human UniPathway:UPA00232 CORIN UniProtKB UniProtKB {GO:0007565=PMID:22437503, GO:0004252=PMID:10880574, GO:0009986=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0005576=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0016486=PMID:10880574, GO:0008217=GO_REF:0000024, GO:0006508=GO_REF:0000037, GO:0035813=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0003050=GO_REF:0000024, GO:0070008=GO_REF:0000002, GO:0005044=GO_REF:0000002} Q9Y5Q5 Atrial natriuretic peptide-converting enzyme protein 20120430 {GO:0007565=IMP, GO:0004252=IDA, GO:0009986=IEA, GO:0005886=IEA, GO:0005576=IEA, GO:0016020=IEA, GO:0016486=IDA, GO:0008217=ISS, GO:0006508=IEA, GO:0035813=ISS, GO:0016021=IEA, GO:0003050=ISS, GO:0070008=IEA, GO:0005044=IEA} female pregnancy, peptide hormone processing, proteolysis, regulation of blood pressure, regulation of renal sodium excretion, regulation of systemic arterial blood pressure by atrial natriuretic peptide cell surface, extracellular region, integral to membrane, membrane, plasma membrane scavenger receptor activity, serine-type endopeptidase activity, serine-type exopeptidase activity Human UniProtKB:Q9Z319 CORO1A IntAct UniProtKB {GO:0008092=GO_REF:0000024, GO:0005515=PMID:21988832, GO:0006909=PMID:17442961, GO:0030036=PMID:17442961, GO:0008360=GO_REF:0000033, GO:0005884=PMID:15800061, GO:0006928=PMID:17341475, GO:0005634=PMID:17341475, GO:0042803=PMID:15601263, GO:0042802=GO_REF:0000019, GO:0051015=PMID:15601263, GO:0030833=GO_REF:0000019, GO:0048873=GO_REF:0000019, GO:0042102=GO_REF:0000019, GO:0030670=GO_REF:0000039, GO:0007015=GO_REF:0000019, GO:0006816=GO_REF:0000019, GO:0034097=GO_REF:0000019, GO:0043029=GO_REF:0000019, GO:0031252=GO_REF:0000019, GO:0001772=GO_REF:0000019, GO:0030335=GO_REF:0000019, GO:0030595=GO_REF:0000033, GO:0031589=PMID:17442961, GO:0001845=PMID:12132654, GO:0008022=PMID:9365277, GO:0050918=PMID:17442961, GO:0043234=PMID:11094157, GO:0032796=GO_REF:0000033, GO:0045087=PMID:17341475, GO:0051126=PMID:17442961, GO:0030864=PMID:15800061, GO:0043548=PMID:11094157} P31146 Coronin-1A protein 20130415 {GO:0008092=ISS, GO:0005515=IPI, GO:0006909=IMP, GO:0030036=IMP, GO:0008360=IBA, GO:0005884=IDA, GO:0006928=NAS, GO:0005634=IDA, GO:0042803=IDA, GO:0042802=IEA, GO:0051015=IDA, GO:0030833=IEA, GO:0048873=IEA, GO:0042102=IEA, GO:0030670=IEA, GO:0007015=IEA, GO:0006816=IEA, GO:0034097=IEA, GO:0043029=IEA, GO:0031252=IEA, GO:0001772=IEA, GO:0030335=IEA, GO:0030595=IBA, GO:0031589=IMP, GO:0001845=IMP, GO:0008022=IPI, GO:0050918=IDA, GO:0043234=IDA, GO:0032796=IBA, GO:0045087=NAS, GO:0051126=IDA, GO:0030864=IDA, GO:0043548=IDA} T cell homeostasis, actin cytoskeleton organization, actin filament organization, calcium ion transport, cell-substrate adhesion, cellular component movement, homeostasis of number of cells within a tissue, innate immune response, leukocyte chemotaxis, negative regulation of actin nucleation, phagocytosis, phagolysosome assembly, positive chemotaxis, positive regulation of T cell proliferation, positive regulation of cell migration, regulation of actin filament polymerization, regulation of cell shape, response to cytokine stimulus, uropod organization actin filament, cell leading edge, cortical actin cytoskeleton, immunological synapse, nucleus, phagocytic vesicle membrane, protein complex actin filament binding, cytoskeletal protein binding, identical protein binding, phosphatidylinositol 3-kinase binding, protein C-terminus binding, protein binding, protein homodimerization activity Human UniProtKB:P40763 CORO1B IntAct UniProtKB {GO:0005515=PMID:17350576, GO:0005737=GO_REF:0000037, GO:0051015=GO_REF:0000033, GO:0030036=GO_REF:0000033, GO:0015629=GO_REF:0000033} Q9BR76 Coronin-1B protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0051015=IBA, GO:0030036=IBA, GO:0015629=IBA} actin cytoskeleton organization actin cytoskeleton, cytoplasm actin filament binding, protein binding Human UniProtKB:Q8WYL5 CORO1C PINC UniProtKB {GO:0006909=PMID:9778037, GO:0007165=PMID:9778037, GO:0051015=GO_REF:0000033, GO:0030036=GO_REF:0000033, GO:0015629=GO_REF:0000033} Q9ULV4 Coronin-1C protein 20030904 {GO:0006909=TAS, GO:0007165=TAS, GO:0051015=IBA, GO:0030036=IBA, GO:0015629=IBA} actin cytoskeleton organization, phagocytosis, signal transduction actin cytoskeleton actin filament binding Human CORO2A PINC UniProtKB {GO:0035556=PMID:8985118, GO:0051015=GO_REF:0000033, GO:0030036=GO_REF:0000033, GO:0017053=PMID:12628926, GO:0015629=GO_REF:0000033} Q92828 Coronin-2A protein 20030904 {GO:0035556=TAS, GO:0051015=IBA, GO:0030036=IBA, GO:0017053=IDA, GO:0015629=IBA} actin cytoskeleton organization, intracellular signal transduction actin cytoskeleton, transcriptional repressor complex actin filament binding Human CORO2B UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0051015=GO_REF:0000033, GO:0030036=PMID:10224093, GO:0016020=PMID:10224093, GO:0003779=PMID:10224093, GO:0015629=GO_REF:0000033} Q9UQ03 Coronin-2B protein 20030403 {GO:0005737=IEA, GO:0051015=IBA, GO:0030036=NAS, GO:0016020=NAS, GO:0003779=NAS, GO:0015629=IBA} actin cytoskeleton organization actin cytoskeleton, cytoplasm, membrane actin binding, actin filament binding Human CORO7 UniProtKB UniProtKB {GO:0051015=GO_REF:0000033, GO:0030036=GO_REF:0000033, GO:0005794=GO_REF:0000024, GO:0000139=GO_REF:0000039, GO:0016023=GO_REF:0000039, GO:0016021=GO_REF:0000024, GO:0015629=GO_REF:0000033, GO:0005829=GO_REF:0000039} P57737 Coronin-7 protein 20041201 {GO:0051015=IRD, GO:0030036=IRD, GO:0005794=ISS, GO:0000139=IEA, GO:0016023=IEA, GO:0016021=ISS, GO:0015629=IRD, GO:0005829=IEA} actin cytoskeleton organization Golgi apparatus, Golgi membrane, actin cytoskeleton, cytoplasmic membrane-bounded vesicle, cytosol, integral to membrane actin filament binding Human UniProtKB:Q9D2V7 CORT UniProtKB UniProtKB {GO:0001664=PMID:12915402, GO:0007268=PMID:9125122, GO:0005184=PMID:9125122, GO:0007193=PMID:9125122, GO:0005615=PMID:9125122} O00230 Cortistatin protein 20120802 {GO:0001664=IPI, GO:0007268=NAS, GO:0005184=IDA, GO:0007193=IDA, GO:0005615=NAS} adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, synaptic transmission extracellular space G-protein coupled receptor binding, neuropeptide hormone activity Human COTL1 IntAct UniProtKB {GO:0005515=PMID:11297527, GO:0005622=GO_REF:0000002, GO:0008150=GO_REF:0000015, GO:0031965=GO_REF:0000039, GO:0005737=GO_REF:0000037, GO:0050832=GO_REF:0000019, GO:0003779=PMID:11583571, GO:0005575=GO_REF:0000015, GO:0005856=GO_REF:0000039, GO:0019899=PMID:11297527} Q14019 Coactosin-like protein protein 20130415 {GO:0005515=IPI, GO:0005622=IEA, GO:0008150=ND, GO:0031965=IEA, GO:0005737=IEA, GO:0050832=IEA, GO:0003779=IDA, GO:0005575=ND, GO:0005856=IEA, GO:0019899=IPI} biological_process, defense response to fungus cellular_component, cytoplasm, cytoskeleton, intracellular, nuclear membrane actin binding, enzyme binding, protein binding Human UniProtKB:P09917 COX11 PINC UniProtKB {GO:0005739=PMID:9878253, GO:0008535=PMID:9878253, GO:0007585=PMID:9878253, GO:0005507=GO_REF:0000002, GO:0004129=PMID:9878253, GO:0005743=GO_REF:0000039, GO:0009055=PMID:9878253, GO:0016021=GO_REF:0000037} Q9Y6N1 Cytochrome c oxidase assembly protein COX11, mitochondrial protein 20030904 {GO:0005739=TAS, GO:0008535=TAS, GO:0007585=TAS, GO:0005507=IEA, GO:0004129=TAS, GO:0005743=IEA, GO:0009055=TAS, GO:0016021=IEA} respiratory chain complex IV assembly, respiratory gaseous exchange integral to membrane, mitochondrial inner membrane, mitochondrion copper ion binding, cytochrome-c oxidase activity, electron carrier activity Human COX15 BHF-UCL UniProtKB {GO:0005739=PMID:9878253, GO:0045333=PMID:12474143, GO:0005746=PMID:9878253, GO:0008535=PMID:12474143, GO:0007585=PMID:9878253, GO:0006123=PMID:12474143, GO:0004129=PMID:12474143, GO:0016021=GO_REF:0000037, GO:0016627=GO_REF:0000002, GO:0006784=PMID:12474143, GO:0055114=PMID:9878253} Q7KZN9 Cytochrome c oxidase assembly protein COX15 homolog protein 20130214 {GO:0005739=IDA, GO:0045333=IC, GO:0005746=TAS, GO:0008535=IMP, GO:0007585=TAS, GO:0006123=IC, GO:0004129=IGI, GO:0016021=IEA, GO:0016627=IEA, GO:0006784=IGI, GO:0055114=TAS} cellular respiration, heme a biosynthetic process, mitochondrial electron transport, cytochrome c to oxygen, oxidation-reduction process, respiratory chain complex IV assembly, respiratory gaseous exchange integral to membrane, mitochondrial respiratory chain, mitochondrion cytochrome-c oxidase activity, oxidoreductase activity, acting on the CH-CH group of donors Human COX17 PINC UniProtKB {GO:0007507=GO_REF:0000019, GO:0005758=GO_REF:0000039, GO:0005737=PMID:9050918, GO:0005507=PMID:9050918, GO:0007420=GO_REF:0000019, GO:0006091=PMID:9050918, GO:0016531=GO_REF:0000002, GO:0006825=GO_REF:0000002} Q14061 Cytochrome c oxidase copper chaperone protein 20030904 {GO:0007507=IEA, GO:0005758=IEA, GO:0005737=TAS, GO:0005507=TAS, GO:0007420=IEA, GO:0006091=TAS, GO:0016531=IEA, GO:0006825=IEA} brain development, copper ion transport, generation of precursor metabolites and energy, heart development cytoplasm, mitochondrial intermembrane space copper chaperone activity, copper ion binding Human COX4I1 InterPro UniProtKB {GO:0005739=GO_REF:0000052, GO:0022904=Reactome:REACT_22393, GO:0007584=GO_REF:0000019, GO:0004129=GO_REF:0000002, GO:0005743=Reactome:REACT_6149, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0006091=PMID:2157630} Q86WV2 COX4I1 protein protein 20130413 {GO:0005739=IDA, GO:0022904=TAS, GO:0007584=IEA, GO:0004129=IEA, GO:0005743=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0006091=TAS} generation of precursor metabolites and energy, respiratory electron transport chain, response to nutrient, small molecule metabolic process mitochondrial inner membrane, mitochondrion, nucleus cytochrome-c oxidase activity Human InterPro:IPR004203 COX4I2 UniProtKB UniProtKB {GO:0045333=PMID:11911854, GO:0004129=PMID:11311561, GO:0006091=PMID:11311561, GO:0005751=PMID:11311561, GO:0055114=PMID:11311561} Q96KJ9 Cytochrome c oxidase subunit 4 isoform 2, mitochondrial protein 20020730 {GO:0045333=NAS, GO:0004129=IDA, GO:0006091=NAS, GO:0005751=IC, GO:0055114=NAS} cellular respiration, generation of precursor metabolites and energy, oxidation-reduction process mitochondrial respiratory chain complex IV cytochrome-c oxidase activity Human COX5A Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0004129=GO_REF:0000002, GO:0005743=Reactome:REACT_6149, GO:0009055=PMID:2853101, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037} P20674 Cytochrome c oxidase subunit 5A, mitochondrial protein 20050517 {GO:0022904=TAS, GO:0004129=IEA, GO:0005743=TAS, GO:0009055=TAS, GO:0044281=TAS, GO:0046872=IEA} respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane cytochrome-c oxidase activity, electron carrier activity, metal ion binding Human COX5B HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0022904=Reactome:REACT_22393, GO:0007585=PMID:1646156, GO:0004129=GO_REF:0000002, GO:0005743=Reactome:REACT_6149, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037} P10606 Cytochrome c oxidase subunit 5B, mitochondrial protein 20101115 {GO:0005739=IDA, GO:0022904=TAS, GO:0007585=TAS, GO:0004129=IEA, GO:0005743=TAS, GO:0044281=TAS, GO:0046872=IEA} respiratory electron transport chain, respiratory gaseous exchange, small molecule metabolic process mitochondrial inner membrane, mitochondrion cytochrome-c oxidase activity, metal ion binding Human COX6A1 Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0004129=GO_REF:0000002, GO:0005743=Reactome:REACT_6149, GO:0044281=Reactome:REACT_111217, GO:0006091=PMID:2549515, GO:0005751=GO_REF:0000002} P12074 Cytochrome c oxidase subunit 6A1, mitochondrial protein 20050517 {GO:0022904=TAS, GO:0004129=IEA, GO:0005743=TAS, GO:0044281=TAS, GO:0006091=TAS, GO:0005751=IEA} generation of precursor metabolites and energy, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial respiratory chain complex IV cytochrome-c oxidase activity Human COX6A2 PINC UniProtKB {GO:0004129=GO_REF:0000002, GO:0006091=PMID:9284905, GO:0005751=GO_REF:0000002} Q02221 Cytochrome c oxidase subunit 6A2, mitochondrial protein 20030904 {GO:0004129=IEA, GO:0006091=TAS, GO:0005751=IEA} generation of precursor metabolites and energy mitochondrial respiratory chain complex IV cytochrome-c oxidase activity Human COX6B1 HPA UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005739=GO_REF:0000052, GO:0005758=GO_REF:0000039, GO:0004129=PMID:2172092, GO:0005743=Reactome:REACT_6149, GO:0044281=Reactome:REACT_111217, GO:0055114=GO_REF:0000029} P14854 Cytochrome c oxidase subunit 6B1 protein 20080205 {GO:0022904=TAS, GO:0005739=IDA, GO:0005758=IEA, GO:0004129=NAS, GO:0005743=TAS, GO:0044281=TAS, GO:0055114=NAS} oxidation-reduction process, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrion cytochrome-c oxidase activity Human COX6C Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0004129=GO_REF:0000002, GO:0005743=Reactome:REACT_6149, GO:0044281=Reactome:REACT_111217, GO:0006091=PMID:2849755, GO:0016021=GO_REF:0000037} P09669 Cytochrome c oxidase subunit 6C protein 20050517 {GO:0022904=TAS, GO:0004129=IEA, GO:0005743=TAS, GO:0044281=TAS, GO:0006091=TAS, GO:0016021=IEA} generation of precursor metabolites and energy, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane cytochrome-c oxidase activity Human COX7A2 InterPro UniProtKB {GO:0005746=GO_REF:0000002, GO:0004129=GO_REF:0000002, GO:0009055=GO_REF:0000002} P14406 Cytochrome c oxidase subunit 7A2, mitochondrial protein 20130413 {GO:0005746=IEA, GO:0004129=IEA, GO:0009055=IEA} mitochondrial respiratory chain cytochrome-c oxidase activity, electron carrier activity Human InterPro:IPR003177 COX7A2L Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005746=GO_REF:0000002, GO:0004129=GO_REF:0000002, GO:0005743=Reactome:REACT_6149, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217} O14548 Cytochrome c oxidase subunit 7A-related protein, mitochondrial protein 20050517 {GO:0022904=TAS, GO:0005746=IEA, GO:0004129=IEA, GO:0005743=TAS, GO:0009055=IEA, GO:0044281=TAS} respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial respiratory chain cytochrome-c oxidase activity, electron carrier activity Human COX7B Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005746=GO_REF:0000002, GO:0004129=GO_REF:0000002, GO:0005743=Reactome:REACT_6149, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0007417=PMID:23122588} P24311 Cytochrome c oxidase subunit 7B, mitochondrial protein 20050517 {GO:0022904=TAS, GO:0005746=IEA, GO:0004129=IEA, GO:0005743=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0007417=IMP} central nervous system development, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane, mitochondrial respiratory chain cytochrome-c oxidase activity Human COX7C Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0004129=GO_REF:0000002, GO:0005743=Reactome:REACT_6149, GO:0044281=Reactome:REACT_111217, GO:0006091=PMID:2155413, GO:0016021=GO_REF:0000037} P15954 Cytochrome c oxidase subunit 7C, mitochondrial protein 20050517 {GO:0022904=TAS, GO:0004129=IEA, GO:0005743=TAS, GO:0044281=TAS, GO:0006091=TAS, GO:0016021=IEA} generation of precursor metabolites and energy, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane cytochrome-c oxidase activity Human COX8A Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0004129=GO_REF:0000002, GO:0005743=Reactome:REACT_6149, GO:0044281=Reactome:REACT_111217, GO:0006091=PMID:2543673, GO:0016021=GO_REF:0000037} P10176 Cytochrome c oxidase subunit 8A, mitochondrial protein 20050517 {GO:0022904=TAS, GO:0004129=IEA, GO:0005743=TAS, GO:0044281=TAS, GO:0006091=TAS, GO:0016021=IEA} generation of precursor metabolites and energy, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane cytochrome-c oxidase activity Human CP BHF-UCL UniProtKB {GO:0006879=Reactome:REACT_25060, GO:0004322=GO_REF:0000003, GO:0005507=GO_REF:0000019, GO:0051087=PMID:19996109, GO:0005576=Reactome:REACT_25098, GO:0005615=PMID:19996109, GO:0055085=Reactome:REACT_19118, GO:0006825=GO_REF:0000037} P00450 Ceruloplasmin protein 20100113 {GO:0006879=TAS, GO:0004322=IEA, GO:0005507=IEA, GO:0051087=IPI, GO:0005576=TAS, GO:0005615=IDA, GO:0055085=TAS, GO:0006825=IEA} cellular iron ion homeostasis, copper ion transport, transmembrane transport extracellular region, extracellular space chaperone binding, copper ion binding, ferroxidase activity Human UniProtKB:P10909 CPA1 UniProtKB UniProtKB {GO:0006508=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005615=PMID:2920728, GO:0004181=GO_REF:0000002} P15085 Carboxypeptidase A1 protein 20060508 {GO:0006508=IEA, GO:0008270=IEA, GO:0005615=IDA, GO:0004181=IEA} proteolysis extracellular space metallocarboxypeptidase activity, zinc ion binding Human CPA4 UniProtKB UniProtKB {GO:0016573=PMID:10383164, GO:0004180=GO_REF:0000002, GO:0006508=GO_REF:0000029, GO:0005576=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0004181=PMID:10383164} Q9UI42 Carboxypeptidase A4 protein 20061026 {GO:0016573=NAS, GO:0004180=IEA, GO:0006508=NAS, GO:0005576=IEA, GO:0008270=IEA, GO:0005575=ND, GO:0004181=NAS} histone acetylation, proteolysis cellular_component, extracellular region carboxypeptidase activity, metallocarboxypeptidase activity, zinc ion binding Human CPAMD8 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0004866=GO_REF:0000002, GO:0004867=GO_REF:0000037, GO:0005576=GO_REF:0000002, GO:0005615=GO_REF:0000002} Q8IZJ3 C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8 protein 20130413 {GO:0005886=IEA, GO:0004866=IEA, GO:0004867=IEA, GO:0005576=IEA, GO:0005615=IEA} extracellular region, extracellular space, plasma membrane endopeptidase inhibitor activity, serine-type endopeptidase inhibitor activity Human UniProtKB-SubCell:SL-0039 CPB1 PINC UniProtKB {GO:0006508=GO_REF:0000037, GO:0004180=PMID:1370825, GO:0005576=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0004181=GO_REF:0000002} P15086 Carboxypeptidase B protein 20030904 {GO:0006508=IEA, GO:0004180=TAS, GO:0005576=IEA, GO:0008270=IEA, GO:0004181=IEA} proteolysis extracellular region carboxypeptidase activity, metallocarboxypeptidase activity, zinc ion binding Human CPB2 ENSEMBL UniProtKB {GO:0009408=GO_REF:0000019, GO:0007596=GO_REF:0000037, GO:0042493=GO_REF:0000019, GO:0006508=GO_REF:0000019, GO:0051918=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0042730=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0004181=GO_REF:0000002} Q96IY4 Carboxypeptidase B2 protein 20130413 {GO:0009408=IEA, GO:0007596=IEA, GO:0042493=IEA, GO:0006508=IEA, GO:0051918=IEA, GO:0008270=IEA, GO:0042730=IEA, GO:0005615=IEA, GO:0004181=IEA} blood coagulation, fibrinolysis, negative regulation of fibrinolysis, proteolysis, response to drug, response to heat extracellular space metallocarboxypeptidase activity, zinc ion binding Human Ensembl:ENSRNOP00000014909 CPD PINC UniProtKB {GO:0004185=GO_REF:0000002, GO:0016020=PMID:9064476, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0004181=GO_REF:0000002} O75976 Carboxypeptidase D protein 20030904 {GO:0004185=IEA, GO:0016020=TAS, GO:0006508=IEA, GO:0008270=IEA, GO:0016021=IEA, GO:0004181=IEA} proteolysis integral to membrane, membrane metallocarboxypeptidase activity, serine-type carboxypeptidase activity, zinc ion binding Human CPE BHF-UCL UniProtKB {GO:0005794=PMID:19166515, GO:0005886=PMID:9019408, GO:0005576=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0003214=PMID:19593212, GO:0072657=PMID:19166515, GO:0042043=PMID:19166515, GO:0007218=PMID:2334405, GO:0008152=PMID:7663508, GO:0006508=GO_REF:0000037, GO:0004180=PMID:9019408, GO:0008270=GO_REF:0000002, GO:0030070=GO_REF:0000019, GO:0050839=PMID:19166515, GO:0044267=Reactome:REACT_17015, GO:0006464=PMID:2334405, GO:0030658=GO_REF:0000039, GO:0030667=Reactome:REACT_15374, GO:0004181=GO_REF:0000002} P16870 Carboxypeptidase E protein 20100819 {GO:0005794=IDA, GO:0005886=TAS, GO:0005576=IEA, GO:0005634=IEA, GO:0003214=IMP, GO:0072657=IDA, GO:0042043=IPI, GO:0007218=NAS, GO:0008152=TAS, GO:0006508=IEA, GO:0004180=TAS, GO:0008270=IEA, GO:0030070=IEA, GO:0050839=IPI, GO:0044267=TAS, GO:0006464=NAS, GO:0030658=IEA, GO:0030667=TAS, GO:0004181=IEA} cardiac left ventricle morphogenesis, cellular protein metabolic process, cellular protein modification process, insulin processing, metabolic process, neuropeptide signaling pathway, protein localization to membrane, proteolysis Golgi apparatus, extracellular region, nucleus, plasma membrane, secretory granule membrane, transport vesicle membrane carboxypeptidase activity, cell adhesion molecule binding, metallocarboxypeptidase activity, neurexin family protein binding, zinc ion binding Human CPEB1 UniProtKB UniProtKB {GO:0006397=GO_REF:0000037, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0000932=GO_REF:0000039, GO:0045211=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0014069=GO_REF:0000039, GO:0003676=GO_REF:0000002, GO:0006417=GO_REF:0000037} Q9BZB8 Cytoplasmic polyadenylation element-binding protein 1 protein 20130413 {GO:0006397=IEA, GO:0030054=IEA, GO:0005886=IEA, GO:0000166=IEA, GO:0000932=IEA, GO:0045211=IEA, GO:0003723=IEA, GO:0014069=IEA, GO:0003676=IEA, GO:0006417=IEA} mRNA processing, regulation of translation cell junction, cytoplasmic mRNA processing body, plasma membrane, postsynaptic density, postsynaptic membrane RNA binding, nucleic acid binding, nucleotide binding Human UniProtKB-SubCell:SL-0297 CPEB4 ENSEMBL UniProtKB {GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000019, GO:0045202=GO_REF:0000019, GO:0003676=GO_REF:0000002} Q17RY0 Cytoplasmic polyadenylation element-binding protein 4 protein 20130413 {GO:0000166=IEA, GO:0003723=IEA, GO:0045202=IEA, GO:0003676=IEA} synapse RNA binding, nucleic acid binding, nucleotide binding Human Ensembl:ENSMUSP00000020543 CPLX1 Reactome UniProtKB {GO:0019905=GO_REF:0000002, GO:0005326=GO_REF:0000019, GO:0045202=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0006887=PMID:7553862, GO:0014047=Reactome:REACT_12591, GO:0016079=GO_REF:0000019, GO:0007269=Reactome:REACT_13723, GO:0030425=GO_REF:0000019, GO:0005829=Reactome:REACT_23973, GO:0043025=GO_REF:0000019, GO:0006836=GO_REF:0000002, GO:0017075=GO_REF:0000019, GO:0070032=GO_REF:0000019, GO:0030073=GO_REF:0000019} O14810 Complexin-1 protein 20130213 {GO:0019905=IEA, GO:0005326=IEA, GO:0045202=IEA, GO:0007268=TAS, GO:0006887=TAS, GO:0014047=TAS, GO:0016079=IEA, GO:0007269=TAS, GO:0030425=IEA, GO:0005829=TAS, GO:0043025=IEA, GO:0006836=IEA, GO:0017075=IEA, GO:0070032=IEA, GO:0030073=IEA} exocytosis, glutamate secretion, insulin secretion, neurotransmitter secretion, neurotransmitter transport, synaptic transmission, synaptic vesicle exocytosis cytosol, dendrite, neuronal cell body, synapse, synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex neurotransmitter transporter activity, syntaxin binding, syntaxin-1 binding Human CPLX2 PINC UniProtKB {GO:0019905=GO_REF:0000002, GO:0043303=GO_REF:0000037, GO:0031201=GO_REF:0000019, GO:0045202=GO_REF:0000019, GO:0016079=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0030154=GO_REF:0000037, GO:0006904=PMID:7553862, GO:0007399=GO_REF:0000037, GO:0005829=GO_REF:0000039, GO:0031915=GO_REF:0000024, GO:0043025=GO_REF:0000019, GO:0006836=GO_REF:0000002, GO:0017075=GO_REF:0000019} Q6PUV4 Complexin-2 protein 20040715 {GO:0019905=IEA, GO:0043303=IEA, GO:0031201=IEA, GO:0045202=IEA, GO:0016079=IEA, GO:0030425=IEA, GO:0030154=IEA, GO:0006904=TAS, GO:0007399=IEA, GO:0005829=IEA, GO:0031915=ISS, GO:0043025=IEA, GO:0006836=IEA, GO:0017075=IEA} cell differentiation, mast cell degranulation, nervous system development, neurotransmitter transport, positive regulation of synaptic plasticity, synaptic vesicle exocytosis, vesicle docking involved in exocytosis SNARE complex, cytosol, dendrite, neuronal cell body, synapse syntaxin binding, syntaxin-1 binding Human CPM HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0004180=PMID:7797563, GO:0005730=GO_REF:0000052, GO:0006508=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0031225=GO_REF:0000037, GO:0009653=PMID:7797563, GO:0004181=GO_REF:0000002} P14384 Carboxypeptidase M protein 20101115 {GO:0005737=IDA, GO:0005886=IDA, GO:0004180=TAS, GO:0005730=IDA, GO:0006508=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0031225=IEA, GO:0009653=TAS, GO:0004181=IEA} anatomical structure morphogenesis, proteolysis anchored to membrane, cytoplasm, nucleolus, nucleus, plasma membrane carboxypeptidase activity, metallocarboxypeptidase activity, zinc ion binding Human CPN1 UniProtKB UniProtKB {GO:0006508=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005615=GO_REF:0000039, GO:0004181=GO_REF:0000002} P15169 Carboxypeptidase N catalytic chain protein 20130413 {GO:0006508=IEA, GO:0051384=IEA, GO:0008270=IEA, GO:0005615=IEA, GO:0004181=IEA} proteolysis, response to glucocorticoid stimulus extracellular space metallocarboxypeptidase activity, zinc ion binding Human UniProtKB-SubCell:SL-0112 CPN2 GOC UniProtKB {GO:0050790=PMID:2378615, GO:0050821=PMID:2378615, GO:0030234=PMID:2378615, GO:0005576=PMID:2378615} P22792 Carboxypeptidase N subunit 2 protein 20130413 {GO:0050790=NAS, GO:0050821=NAS, GO:0030234=NAS, GO:0005576=NAS} protein stabilization, regulation of catalytic activity extracellular region enzyme regulator activity Human CPNE1 HPA UniProtKB {GO:0005544=PMID:9430674, GO:0006629=PMID:9430674, GO:0005215=PMID:9430674, GO:0005730=GO_REF:0000052, GO:0001786=PMID:9430674, GO:0005634=GO_REF:0000052, GO:0016192=PMID:9430674} Q99829 Copine-1 protein 20120912 {GO:0005544=TAS, GO:0006629=TAS, GO:0005215=TAS, GO:0005730=IDA, GO:0001786=IDA, GO:0005634=IDA, GO:0016192=TAS} lipid metabolic process, vesicle-mediated transport nucleolus, nucleus calcium-dependent phospholipid binding, phosphatidylserine binding, transporter activity NOT Human CPNE2 null null {} null null null null {} null null null CPNE3 PINC UniProtKB {GO:0006629=PMID:9430674, GO:0005544=PMID:11041869, GO:0005215=PMID:9430674, GO:0005737=PMID:11041869, GO:0004674=PMID:11041869, GO:0016192=PMID:9430674, GO:0005829=PMID:12949241} O75131 Copine-3 protein 20030904 {GO:0006629=TAS, GO:0005544=TAS, GO:0005215=TAS, GO:0005737=NAS, GO:0004674=IDA, GO:0016192=TAS, GO:0005829=IDA} lipid metabolic process, vesicle-mediated transport cytoplasm, cytosol calcium-dependent phospholipid binding, protein serine/threonine kinase activity, transporter activity Human CPNE4 null null {} null null null null {} null null null CPNE5 ENSEMBL UniProtKB {GO:0043005=GO_REF:0000019, GO:0043025=GO_REF:0000019} Q9HCH3 Copine-5 protein 20130413 {GO:0043005=IEA, GO:0043025=IEA} neuron projection, neuronal cell body Human Ensembl:ENSMUSP00000024805 CPNE6 PINC UniProtKB {GO:0006629=PMID:9645480, GO:0005215=PMID:9645480, GO:0030424=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0005509=PMID:9645480, GO:0001786=GO_REF:0000019, GO:0007268=PMID:9645480, GO:0016192=PMID:9645480, GO:0030425=GO_REF:0000019, GO:0007399=PMID:9645480} O95741 Copine-6 protein 20030904 {GO:0006629=TAS, GO:0005215=TAS, GO:0030424=IEA, GO:0016020=IEA, GO:0005509=TAS, GO:0001786=IEA, GO:0007268=TAS, GO:0016192=TAS, GO:0030425=IEA, GO:0007399=TAS} lipid metabolic process, nervous system development, synaptic transmission, vesicle-mediated transport axon, dendrite, membrane calcium ion binding, phosphatidylserine binding, transporter activity Human CPNE7 GOC UniProtKB {GO:0006629=PMID:10534407, GO:0005215=PMID:10534407, GO:0006810=PMID:10534407} Q9UBL6 Copine-7 protein 20130413 {GO:0006629=TAS, GO:0005215=TAS, GO:0006810=TAS} lipid metabolic process, transport transporter activity Human CPNE8 null null {} null null null null {} null null null CPNE9 null null {} null null null null {} null null null CPOX HPA UniProtKB {GO:0010288=GO_REF:0000019, GO:0046685=GO_REF:0000019, GO:0005743=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0006782=GO_REF:0000041, GO:0042803=PMID:16176984, GO:0006783=Reactome:REACT_9465, GO:0005739=GO_REF:0000052, GO:0005758=Reactome:REACT_9421, GO:0005737=GO_REF:0000052, GO:0051597=GO_REF:0000019, GO:0006778=Reactome:REACT_9431, GO:0006779=GO_REF:0000002, GO:0010039=GO_REF:0000019, GO:0017085=GO_REF:0000019, GO:0004109=Reactome:REACT_9421} P36551 Coproporphyrinogen-III oxidase, mitochondrial protein 20101115 {GO:0010288=IEA, GO:0046685=IEA, GO:0005743=IEA, GO:0044281=TAS, GO:0006782=IEA, GO:0042803=IDA, GO:0006783=TAS, GO:0005739=IDA, GO:0005758=TAS, GO:0005737=IDA, GO:0051597=IEA, GO:0006778=TAS, GO:0006779=IEA, GO:0010039=IEA, GO:0017085=IEA, GO:0004109=TAS} heme biosynthetic process, porphyrin-containing compound biosynthetic process, porphyrin-containing compound metabolic process, protoporphyrinogen IX biosynthetic process, response to arsenic-containing substance, response to insecticide, response to iron ion, response to lead ion, response to methylmercury, small molecule metabolic process cytoplasm, mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrion coproporphyrinogen oxidase activity, protein homodimerization activity Human CPPED1 UniProtKB UniProtKB {GO:0016787=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q9BRF8 Calcineurin-like phosphoesterase domain-containing protein 1 protein 20130413 {GO:0016787=IEA, GO:0046872=IEA} hydrolase activity, metal ion binding Human UniProtKB-KW:KW-0479 CPS1 BHF-UCL UniProtKB {GO:0042645=PMID:18063578, GO:0019240=PMID:14718356, GO:0005515=PMID:12620389, GO:0005743=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0014075=GO_REF:0000019, GO:0032094=GO_REF:0000019, GO:0010043=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0050667=PMID:20031578, GO:0046872=GO_REF:0000002, GO:0072341=PMID:20031578, GO:0034641=Reactome:REACT_13, GO:0005543=GO_REF:0000019, GO:0042594=GO_REF:0000019, GO:0070409=PMID:7416778, GO:0071377=GO_REF:0000019, GO:0045909=PMID:14718356, GO:0005759=Reactome:REACT_1701, GO:0032496=PMID:15897806, GO:0046209=PMID:14718356, GO:0019433=PMID:9711878, GO:0043200=GO_REF:0000019, GO:0055081=GO_REF:0000019, GO:0060416=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0005509=GO_REF:0000019, GO:0005730=GO_REF:0000039, GO:0009636=GO_REF:0000019, GO:0004087=PMID:9711878, GO:0005524=GO_REF:0000037, GO:0044344=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0004175=GO_REF:0000019, GO:0071400=GO_REF:0000019, GO:0007494=GO_REF:0000019, GO:0000050=PMID:1840546, GO:0006543=GO_REF:0000002, GO:0016595=GO_REF:0000019, GO:0071548=GO_REF:0000019, GO:0071320=GO_REF:0000019, GO:0005980=PMID:9711878, GO:0070365=GO_REF:0000019} P31327 "Carbamoyl-phosphate synthase ""ammonia"", mitochondrial" protein 20090218 {GO:0042645=IDA, GO:0019240=NAS, GO:0005515=IPI, GO:0005743=IEA, GO:0044281=TAS, GO:0014075=IEA, GO:0032094=IEA, GO:0010043=IEA, GO:0032403=IEA, GO:0050667=IDA, GO:0046872=IEA, GO:0072341=IDA, GO:0034641=TAS, GO:0005543=IEA, GO:0042594=IEA, GO:0070409=IMP, GO:0071377=IEA, GO:0045909=IMP, GO:0005759=TAS, GO:0032496=IDA, GO:0046209=IMP, GO:0019433=IMP, GO:0043200=IEA, GO:0055081=IEA, GO:0060416=IEA, GO:0042493=IEA, GO:0005509=IEA, GO:0005730=IEA, GO:0009636=IEA, GO:0004087=IMP, GO:0005524=IEA, GO:0044344=IEA, GO:0043234=IEA, GO:0004175=IEA, GO:0071400=IEA, GO:0007494=IEA, GO:0000050=NAS, GO:0006543=IEA, GO:0016595=IEA, GO:0071548=IEA, GO:0071320=IEA, GO:0005980=IMP, GO:0070365=IEA} anion homeostasis, carbamoyl phosphate biosynthetic process, cellular nitrogen compound metabolic process, cellular response to cAMP, cellular response to fibroblast growth factor stimulus, cellular response to glucagon stimulus, cellular response to oleic acid, citrulline biosynthetic process, glutamine catabolic process, glycogen catabolic process, hepatocyte differentiation, homocysteine metabolic process, midgut development, nitric oxide metabolic process, positive regulation of vasodilation, response to amine stimulus, response to amino acid stimulus, response to dexamethasone stimulus, response to drug, response to food, response to growth hormone stimulus, response to lipopolysaccharide, response to starvation, response to toxic substance, response to zinc ion, small molecule metabolic process, triglyceride catabolic process, urea cycle mitochondrial inner membrane, mitochondrial matrix, mitochondrial nucleoid, nucleolus, protein complex ATP binding, calcium ion binding, carbamoyl-phosphate synthase (ammonia) activity, endopeptidase activity, glutamate binding, metal ion binding, modified amino acid binding, phospholipid binding, protein binding, protein complex binding Human CPSF1 Reactome UniProtKB {GO:0006379=PMID:7590244, GO:0005515=PMID:21102410, GO:0008380=Reactome:REACT_1735, GO:0006378=PMID:7590244, GO:0006369=Reactome:REACT_894, GO:0010467=Reactome:REACT_71, GO:0006366=Reactome:REACT_1366, GO:0031124=Reactome:REACT_1849, GO:0006406=Reactome:REACT_1281, GO:0000398=Reactome:REACT_467, GO:0005847=PMID:21102410, GO:0005654=Reactome:REACT_1935, GO:0003730=PMID:7590244} Q10570 Cleavage and polyadenylation specificity factor subunit 1 protein 20130213 {GO:0006379=IDA, GO:0005515=IPI, GO:0008380=TAS, GO:0006378=IDA, GO:0006369=TAS, GO:0010467=TAS, GO:0006366=TAS, GO:0031124=TAS, GO:0006406=TAS, GO:0000398=TAS, GO:0005847=IDA, GO:0005654=TAS, GO:0003730=IDA} RNA splicing, gene expression, mRNA 3'-end processing, mRNA cleavage, mRNA export from nucleus, mRNA polyadenylation, mRNA splicing, via spliceosome, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter mRNA cleavage and polyadenylation specificity factor complex, nucleoplasm mRNA 3'-UTR binding, protein binding Human CPSF2 Reactome UniProtKB {GO:0006379=GO_REF:0000002, GO:0005515=PMID:18688255, GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0006378=GO_REF:0000002, GO:0006369=Reactome:REACT_894, GO:0006398=PMID:18688255, GO:0006366=Reactome:REACT_1366, GO:0003723=GO_REF:0000037, GO:0031124=Reactome:REACT_1849, GO:0006406=Reactome:REACT_1281, GO:0016787=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0005847=PMID:18305108, GO:0005654=Reactome:REACT_1935} Q9P2I0 Cleavage and polyadenylation specificity factor subunit 2 protein 20130213 {GO:0006379=IEA, GO:0005515=IPI, GO:0008380=TAS, GO:0010467=TAS, GO:0006378=IEA, GO:0006369=TAS, GO:0006398=IDA, GO:0006366=TAS, GO:0003723=IEA, GO:0031124=TAS, GO:0006406=TAS, GO:0016787=IEA, GO:0000398=TAS, GO:0005847=IDA, GO:0005654=TAS} RNA splicing, gene expression, histone mRNA 3'-end processing, mRNA 3'-end processing, mRNA cleavage, mRNA export from nucleus, mRNA polyadenylation, mRNA splicing, via spliceosome, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter mRNA cleavage and polyadenylation specificity factor complex, nucleoplasm RNA binding, hydrolase activity, protein binding Human CPSF3 Reactome UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:18688255, GO:0006379=PMID:8929409, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0006378=PMID:8929409, GO:0008409=GO_REF:0000024, GO:0006398=PMID:18688255, GO:0006366=Reactome:REACT_1366, GO:0003723=GO_REF:0000024, GO:0031124=Reactome:REACT_1849, GO:0004521=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0006406=Reactome:REACT_1281, GO:0000398=Reactome:REACT_467, GO:0030529=GO_REF:0000037, GO:0005847=PMID:18305108, GO:0005654=Reactome:REACT_1935} Q9UKF6 Cleavage and polyadenylation specificity factor subunit 3 protein 20130213 {GO:0008380=TAS, GO:0005515=IPI, GO:0006379=TAS, GO:0010467=TAS, GO:0006369=TAS, GO:0006378=TAS, GO:0008409=ISS, GO:0006398=IDA, GO:0006366=TAS, GO:0003723=ISS, GO:0031124=TAS, GO:0004521=ISS, GO:0046872=IEA, GO:0006406=TAS, GO:0000398=TAS, GO:0030529=IEA, GO:0005847=IDA, GO:0005654=TAS} RNA splicing, gene expression, histone mRNA 3'-end processing, mRNA 3'-end processing, mRNA cleavage, mRNA export from nucleus, mRNA polyadenylation, mRNA splicing, via spliceosome, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter mRNA cleavage and polyadenylation specificity factor complex, nucleoplasm, ribonucleoprotein complex 5'-3' exonuclease activity, RNA binding, endoribonuclease activity, metal ion binding, protein binding Human CPSF3L UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0016787=GO_REF:0000037, GO:0005634=GO_REF:0000039} Q5TA45 Integrator complex subunit 11 protein 20130413 {GO:0005737=IEA, GO:0016787=IEA, GO:0005634=IEA} cytoplasm, nucleus hydrolase activity Human UniProtKB-SubCell:SL-0086 CPSF4 HPA UniProtKB {GO:0006397=GO_REF:0000037, GO:0019054=Reactome:REACT_6222, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0019058=Reactome:REACT_6167, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0005739=GO_REF:0000052, GO:0046778=Reactome:REACT_6173, GO:0019048=Reactome:REACT_6323, GO:0005847=PMID:21102410, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_6168} O95639 Cleavage and polyadenylation specificity factor subunit 4 protein 20120912 {GO:0006397=IEA, GO:0019054=TAS, GO:0003723=IEA, GO:0005730=IDA, GO:0019058=TAS, GO:0005634=IDA, GO:0003676=IEA, GO:0005739=IDA, GO:0046778=TAS, GO:0019048=TAS, GO:0005847=IDA, GO:0008270=IEA, GO:0005654=TAS} mRNA processing, modification by virus of host mRNA processing, modulation by virus of host cellular process, viral infectious cycle, virus-host interaction mRNA cleavage and polyadenylation specificity factor complex, mitochondrion, nucleolus, nucleoplasm, nucleus RNA binding, nucleic acid binding, zinc ion binding Human CPSF6 HPA UniProtKB {GO:0006397=PMID:14690600, GO:0005515=PMID:19447967, GO:0006378=PMID:20695905, GO:0051262=PMID:20695905, GO:0003723=PMID:15169763, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0003729=PMID:21295486, GO:0042382=PMID:9659921, GO:0000166=GO_REF:0000002, GO:0030529=PMID:18809582, GO:0005849=PMID:20695905} Q16630 Cleavage and polyadenylation specificity factor subunit 6 protein 20110516 {GO:0006397=IDA, GO:0005515=IPI, GO:0006378=IMP, GO:0051262=IDA, GO:0003723=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0003729=IDA, GO:0042382=IDA, GO:0000166=IEA, GO:0030529=IDA, GO:0005849=IDA} mRNA polyadenylation, mRNA processing, protein tetramerization mRNA cleavage factor complex, nucleolus, nucleus, paraspeckles, ribonucleoprotein complex RNA binding, mRNA binding, nucleic acid binding, nucleotide binding, protein binding NOT Human CPSF7 IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0008380=Reactome:REACT_1735, GO:0006369=Reactome:REACT_894, GO:0010467=Reactome:REACT_71, GO:0051262=PMID:20695905, GO:0006366=Reactome:REACT_1366, GO:0003723=GO_REF:0000037, GO:0031124=Reactome:REACT_1849, GO:0005634=PMID:20695905, GO:0003676=GO_REF:0000002, GO:0000166=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0005849=PMID:20695905, GO:0005654=Reactome:REACT_1935} Q8N684 Cleavage and polyadenylation specificity factor subunit 7 protein 20130415 {GO:0005515=IPI, GO:0008380=TAS, GO:0006369=TAS, GO:0010467=TAS, GO:0051262=IDA, GO:0006366=TAS, GO:0003723=IEA, GO:0031124=TAS, GO:0005634=IDA, GO:0003676=IEA, GO:0000166=IEA, GO:0000398=TAS, GO:0005849=IDA, GO:0005654=TAS} RNA splicing, gene expression, mRNA 3'-end processing, mRNA splicing, via spliceosome, protein tetramerization, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter mRNA cleavage factor complex, nucleoplasm, nucleus RNA binding, nucleic acid binding, nucleotide binding, protein binding Human UniProtKB:P54253 CPT1A HPA UniProtKB {GO:0014070=GO_REF:0000019, GO:0001676=PMID:11350182, GO:0006635=GO_REF:0000041, GO:0016746=GO_REF:0000002, GO:0004095=PMID:11350182, GO:0006853=Reactome:REACT_11082, GO:0042493=GO_REF:0000019, GO:0005743=GO_REF:0000019, GO:0005741=Reactome:REACT_115644, GO:0044281=Reactome:REACT_111217, GO:0042802=GO_REF:0000019, GO:0005739=GO_REF:0000052, GO:0050796=GO_REF:0000019, GO:0032000=GO_REF:0000019, GO:0006006=GO_REF:0000019, GO:0006641=GO_REF:0000019, GO:0051260=GO_REF:0000019, GO:0042755=GO_REF:0000019, GO:0031307=GO_REF:0000024, GO:0009437=PMID:11350182, GO:0044255=Reactome:REACT_22279} P50416 Carnitine O-palmitoyltransferase 1, liver isoform protein 20080205 {GO:0014070=IEA, GO:0001676=IDA, GO:0006635=IEA, GO:0016746=IEA, GO:0004095=IDA, GO:0006853=TAS, GO:0042493=IEA, GO:0005743=IEA, GO:0005741=TAS, GO:0044281=TAS, GO:0042802=IEA, GO:0005739=IDA, GO:0050796=IEA, GO:0032000=IEA, GO:0006006=IEA, GO:0006641=IEA, GO:0051260=IEA, GO:0042755=IEA, GO:0031307=ISS, GO:0009437=IDA, GO:0044255=TAS} carnitine metabolic process, carnitine shuttle, cellular lipid metabolic process, eating behavior, fatty acid beta-oxidation, glucose metabolic process, long-chain fatty acid metabolic process, positive regulation of fatty acid beta-oxidation, protein homooligomerization, regulation of insulin secretion, response to drug, response to organic cyclic compound, small molecule metabolic process, triglyceride metabolic process integral to mitochondrial outer membrane, mitochondrial inner membrane, mitochondrial outer membrane, mitochondrion carnitine O-palmitoyltransferase activity, identical protein binding, transferase activity, transferring acyl groups Human CPT1B Reactome UniProtKB {GO:0005739=PMID:10408760, GO:0006635=GO_REF:0000041, GO:0016746=GO_REF:0000038, GO:0004095=GO_REF:0000003, GO:0006853=Reactome:REACT_11082, GO:0005741=Reactome:REACT_11185, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0015909=GO_REF:0000019, GO:0044255=Reactome:REACT_22279} Q92523 Carnitine O-palmitoyltransferase 1, muscle isoform protein 20130301 {GO:0005739=TAS, GO:0006635=IEA, GO:0016746=IEA, GO:0004095=IEA, GO:0006853=TAS, GO:0005741=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0015909=IEA, GO:0044255=TAS} carnitine shuttle, cellular lipid metabolic process, fatty acid beta-oxidation, long-chain fatty acid transport, small molecule metabolic process integral to membrane, mitochondrial outer membrane, mitochondrion carnitine O-palmitoyltransferase activity, transferase activity, transferring acyl groups Human CPT2 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0006635=GO_REF:0000029, GO:0004095=PMID:1988962, GO:0006853=Reactome:REACT_11082, GO:0005730=GO_REF:0000052, GO:0005743=Reactome:REACT_115927, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0044255=Reactome:REACT_22279} P23786 Carnitine O-palmitoyltransferase 2, mitochondrial protein 20111111 {GO:0005739=IDA, GO:0006635=NAS, GO:0004095=NAS, GO:0006853=TAS, GO:0005730=IDA, GO:0005743=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0044255=TAS} carnitine shuttle, cellular lipid metabolic process, fatty acid beta-oxidation, small molecule metabolic process mitochondrial inner membrane, mitochondrion, nucleolus, nucleus carnitine O-palmitoyltransferase activity Human CPVL UniProtKB UniProtKB {GO:0004185=GO_REF:0000002, GO:0006508=GO_REF:0000037} Q9H3G5 Probable serine carboxypeptidase CPVL protein 20130413 {GO:0004185=IEA, GO:0006508=IEA} proteolysis serine-type carboxypeptidase activity Human UniProtKB-KW:KW-0645 CPXCR1 InterPro UniProtKB {GO:0008270=GO_REF:0000002} Q8N123 CPX chromosomal region candidate gene 1 protein protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR007087 CPXM1 ENSEMBL UniProtKB {GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0007155=GO_REF:0000002, GO:0005615=GO_REF:0000019, GO:0004181=GO_REF:0000002} Q96SM3 Probable carboxypeptidase X1 protein 20130413 {GO:0006508=IEA, GO:0008270=IEA, GO:0007155=IEA, GO:0005615=IEA, GO:0004181=IEA} cell adhesion, proteolysis extracellular space metallocarboxypeptidase activity, zinc ion binding Human Ensembl:ENSMUSP00000028897 CPXM2 InterPro UniProtKB {GO:0006508=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0007155=GO_REF:0000002, GO:0004181=GO_REF:0000002} Q8N436 Inactive carboxypeptidase-like protein X2 protein 20130413 {GO:0006508=IEA, GO:0008270=IEA, GO:0007155=IEA, GO:0004181=IEA} cell adhesion, proteolysis metallocarboxypeptidase activity, zinc ion binding Human InterPro:IPR000834 CR1 Reactome UniProtKB {GO:0030449=Reactome:REACT_118707, GO:0009986=PMID:2972794, GO:0005886=Reactome:REACT_118692, GO:0001861=PMID:2972794, GO:0001855=PMID:2972794, GO:0001851=PMID:2972794, GO:0005887=PMID:6910481, GO:0045087=Reactome:REACT_6802, GO:0006958=GO_REF:0000037, GO:1900005=PMID:2972794, GO:0045959=PMID:10531307, GO:1900004=PMID:6910481, GO:0045957=PMID:10531307, GO:0004877=PMID:2972794} P17927 Complement receptor type 1 protein 20130213 {GO:0030449=TAS, GO:0009986=IDA, GO:0005886=TAS, GO:0001861=IDA, GO:0001855=IDA, GO:0001851=IDA, GO:0005887=IDA, GO:0045087=TAS, GO:0006958=IEA, GO:1900005=IDA, GO:0045959=IDA, GO:1900004=IDA, GO:0045957=IDA, GO:0004877=IDA} complement activation, classical pathway, innate immune response, negative regulation of complement activation, alternative pathway, negative regulation of complement activation, classical pathway, negative regulation of serine-type endopeptidase activity, positive regulation of serine-type endopeptidase activity, regulation of complement activation cell surface, integral to plasma membrane, plasma membrane complement component C3b binding, complement component C3b receptor activity, complement component C4b binding, complement component C4b receptor activity Human CR2 MGI UniProtKB {GO:0042113=GO_REF:0000019, GO:0006955=PMID:2827171, GO:0005886=PMID:2563370, GO:0045087=GO_REF:0000037, GO:0006958=GO_REF:0000037, GO:0016021=PMID:2827171, GO:0042803=PMID:11728339, GO:0009897=GO_REF:0000019, GO:0004888=PMID:2827171, GO:0004875=PMID:2827171} P20023 Complement receptor type 2 protein 20110203 {GO:0042113=IEA, GO:0006955=NAS, GO:0005886=NAS, GO:0045087=IEA, GO:0006958=IEA, GO:0016021=NAS, GO:0042803=IDA, GO:0009897=IEA, GO:0004888=NAS, GO:0004875=NAS} B cell activation, complement activation, classical pathway, immune response, innate immune response external side of plasma membrane, integral to membrane, plasma membrane complement receptor activity, protein homodimerization activity, transmembrane signaling receptor activity Human CRABP1 PINC UniProtKB {GO:0007165=PMID:1309505, GO:0005215=GO_REF:0000002, GO:0001972=GO_REF:0000019, GO:0005501=PMID:1309505, GO:0016918=GO_REF:0000037, GO:0007275=PMID:1309505, GO:0019841=GO_REF:0000037, GO:0005829=GO_REF:0000019} P29762 Cellular retinoic acid-binding protein 1 protein 20030904 {GO:0007165=TAS, GO:0005215=IEA, GO:0001972=IEA, GO:0005501=TAS, GO:0016918=IEA, GO:0007275=TAS, GO:0019841=IEA, GO:0005829=IEA} multicellular organismal development, signal transduction cytosol retinal binding, retinoic acid binding, retinoid binding, retinol binding, transporter activity Human CRABP2 ENSEMBL UniProtKB {GO:0005215=GO_REF:0000002, GO:0006355=PMID:1334086, GO:0005783=GO_REF:0000039, GO:0016918=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0019841=GO_REF:0000037, GO:0007165=PMID:1654334, GO:0005737=GO_REF:0000019, GO:0008544=PMID:1654334, GO:0042573=GO_REF:0000019, GO:0001972=GO_REF:0000019, GO:0005501=PMID:1334086, GO:0035115=GO_REF:0000019} Q5SYZ4 Cellular retinoic acid-binding protein 2 protein 20130413 {GO:0005215=IEA, GO:0006355=TAS, GO:0005783=IEA, GO:0016918=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0019841=IEA, GO:0007165=TAS, GO:0005737=IEA, GO:0008544=TAS, GO:0042573=IEA, GO:0001972=IEA, GO:0005501=TAS, GO:0035115=IEA} embryonic forelimb morphogenesis, epidermis development, regulation of transcription, DNA-dependent, retinoic acid metabolic process, signal transduction cytoplasm, endoplasmic reticulum, nucleolus, nucleus retinal binding, retinoic acid binding, retinoid binding, retinol binding, transporter activity Human Ensembl:ENSMUSP00000005019 CRADD BHF-UCL UniProtKB {GO:0005515=PMID:16652156, GO:0008625=PMID:9044836, GO:0005622=GO_REF:0000002, GO:0070513=PMID:9044836, GO:0005737=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0042981=GO_REF:0000002, GO:0006917=PMID:9044836, GO:0030674=PMID:9044836, GO:0002020=PMID:9044836, GO:0071260=PMID:19593445} P78560 Death domain-containing protein CRADD protein 20090323 {GO:0005515=IPI, GO:0008625=TAS, GO:0005622=IEA, GO:0070513=IPI, GO:0005737=ISS, GO:0005634=ISS, GO:0042981=IEA, GO:0006917=IDA, GO:0030674=IPI, GO:0002020=IPI, GO:0071260=IEP} cellular response to mechanical stimulus, extrinsic apoptotic signaling pathway via death domain receptors, induction of apoptosis, regulation of apoptotic process cytoplasm, intracellular, nucleus death domain binding, protease binding, protein binding, protein binding, bridging Human UniProtKB:P42575 CRAMP1L UniProtKB UniProtKB {GO:0003682=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037} Q96RY5 Protein cramped-like protein 20130413 {GO:0003682=IEA, GO:0005634=IEA, GO:0003677=IEA} nucleus DNA binding, chromatin binding Human UniProtKB-SubCell:SL-0191 CRAT Reactome UniProtKB {GO:0004092=PMID:15099582, GO:0016746=GO_REF:0000002, GO:0005782=Reactome:REACT_16977, GO:0005783=GO_REF:0000039, GO:0005743=GO_REF:0000039, GO:0005102=PMID:20178365, GO:0044281=Reactome:REACT_111217, GO:0019254=PMID:2351134, GO:0005739=PMID:2351134, GO:0006810=GO_REF:0000037, GO:0033540=Reactome:REACT_17062, GO:0044255=Reactome:REACT_16957, GO:0005777=PMID:2351134} P43155 Carnitine O-acetyltransferase protein 20130301 {GO:0004092=IDA, GO:0016746=IEA, GO:0005782=TAS, GO:0005783=IEA, GO:0005743=IEA, GO:0005102=IPI, GO:0044281=TAS, GO:0019254=IDA, GO:0005739=IDA, GO:0006810=IEA, GO:0033540=TAS, GO:0044255=TAS, GO:0005777=IDA} carnitine metabolic process, CoA-linked, cellular lipid metabolic process, fatty acid beta-oxidation using acyl-CoA oxidase, small molecule metabolic process, transport endoplasmic reticulum, mitochondrial inner membrane, mitochondrion, peroxisomal matrix, peroxisome carnitine O-acetyltransferase activity, receptor binding, transferase activity, transferring acyl groups Human CRB1 PINC UniProtKB {GO:0007009=GO_REF:0000019, GO:0005902=GO_REF:0000019, GO:0016324=GO_REF:0000039, GO:0007163=PMID:10508521, GO:0005886=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0007267=PMID:10508521, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0042462=GO_REF:0000019} P82279 Protein crumbs homolog 1 protein 20030904 {GO:0007009=IEA, GO:0005902=IEA, GO:0016324=IEA, GO:0007163=TAS, GO:0005886=IEA, GO:0005509=IEA, GO:0007267=TAS, GO:0005576=IEA, GO:0016021=IEA, GO:0042462=IEA} cell-cell signaling, establishment or maintenance of cell polarity, eye photoreceptor cell development, plasma membrane organization apical plasma membrane, extracellular region, integral to membrane, microvillus, plasma membrane calcium ion binding Human CRB2 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q5IJ48 Protein crumbs homolog 2 protein 20130413 {GO:0005886=IEA, GO:0005509=IEA, GO:0005576=IEA, GO:0016021=IEA} extracellular region, integral to membrane, plasma membrane calcium ion binding Human UniProtKB-SubCell:SL-0039 CRB3 BHF-UCL UniProtKB {GO:0017124=PMID:17332497, GO:0016324=GO_REF:0000039, GO:0070830=Reactome:REACT_19373, GO:0005886=Reactome:REACT_19144, GO:0034329=Reactome:REACT_20676, GO:0019904=PMID:17332497, GO:0005923=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0072659=PMID:17332497, GO:0045216=Reactome:REACT_19331} Q9BUF7 Protein crumbs homolog 3 protein 20110307 {GO:0017124=IPI, GO:0016324=IEA, GO:0070830=TAS, GO:0005886=TAS, GO:0034329=TAS, GO:0019904=IPI, GO:0005923=IEA, GO:0016021=IEA, GO:0072659=IDA, GO:0045216=TAS} cell junction assembly, cell-cell junction organization, protein localization to plasma membrane, tight junction assembly apical plasma membrane, integral to membrane, plasma membrane, tight junction SH3 domain binding, protein domain specific binding Human UniProtKB:Q5T2T1 CRBN HPA UniProtKB {GO:0005515=PMID:20223979, GO:0032463=GO_REF:0000019, GO:0090073=GO_REF:0000019, GO:0016567=PMID:20223979, GO:0005730=GO_REF:0000052, GO:0005634=PMID:20223979, GO:0005737=PMID:20223979, GO:0016020=GO_REF:0000039, GO:0004176=GO_REF:0000002, GO:0006508=GO_REF:0000002, GO:0043161=PMID:20223979, GO:0031464=PMID:20223979, GO:0034766=GO_REF:0000019} Q96SW2 Protein cereblon protein 20111111 {GO:0005515=IPI, GO:0032463=IEA, GO:0090073=IEA, GO:0016567=IMP, GO:0005730=IDA, GO:0005634=IDA, GO:0005737=IDA, GO:0016020=IEA, GO:0004176=IEA, GO:0006508=IEA, GO:0043161=IMP, GO:0031464=IDA, GO:0034766=IEA} negative regulation of ion transmembrane transport, negative regulation of protein homooligomerization, positive regulation of protein homodimerization activity, proteasomal ubiquitin-dependent protein catabolic process, protein ubiquitination, proteolysis Cul4A-RING ubiquitin ligase complex, cytoplasm, membrane, nucleolus, nucleus ATP-dependent peptidase activity, protein binding Human CRCP UniProtKB UniProtKB {GO:0004948=PMID:8622957, GO:0009360=PMID:12482973, GO:0001669=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0003899=PMID:12482973, GO:0005634=GO_REF:0000039, GO:0006383=PMID:12482973, GO:0006351=GO_REF:0000002, GO:0051607=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0007218=GO_REF:0000019, GO:0045087=GO_REF:0000037, GO:0007340=PMID:10067875, GO:0001635=GO_REF:0000019} O75575 DNA-directed RNA polymerase III subunit RPC9 protein 20080312 {GO:0004948=NAS, GO:0009360=IDA, GO:0001669=IEA, GO:0005886=IEA, GO:0003899=IDA, GO:0005634=IEA, GO:0006383=IDA, GO:0006351=IEA, GO:0051607=IEA, GO:0000166=IEA, GO:0007218=IEA, GO:0045087=IEA, GO:0007340=NAS, GO:0001635=IEA} acrosome reaction, defense response to virus, innate immune response, neuropeptide signaling pathway, transcription from RNA polymerase III promoter, transcription, DNA-dependent DNA polymerase III complex, acrosomal vesicle, nucleus, plasma membrane DNA-directed RNA polymerase activity, calcitonin gene-related polypeptide receptor activity, calcitonin receptor activity, nucleotide binding Human CRCT1 null null {} null null null null {} null null null CREB1 BHF-UCL UniProtKB {GO:0005515=PMID:21988832, GO:0008361=GO_REF:0000019, GO:0000790=GO_REF:0000019, GO:0001190=PMID:19861239, GO:0003700=PMID:8798441, GO:0003705=PMID:19861239, GO:0007409=GO_REF:0000019, GO:0051403=Reactome:REACT_21308, GO:0046889=GO_REF:0000024, GO:0002756=Reactome:REACT_6809, GO:0010944=PMID:19861239, GO:0007173=Reactome:REACT_9417, GO:0007411=Reactome:REACT_18266, GO:0002755=Reactome:REACT_27215, GO:0046887=GO_REF:0000019, GO:0003712=PMID:8552098, GO:0001102=PMID:19861239, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0005719=PMID:19861239, GO:0034134=Reactome:REACT_7980, GO:0002224=Reactome:REACT_9020, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0045600=GO_REF:0000024, GO:0000980=PMID:19861239, GO:0005654=Reactome:REACT_147870, GO:0034166=Reactome:REACT_9027, GO:0035666=Reactome:REACT_25281, GO:0045893=GO_REF:0000024, GO:0034162=Reactome:REACT_9047, GO:0034142=Reactome:REACT_6894, GO:0035497=PMID:19861239, GO:0021983=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0005634=GO_REF:0000052, GO:0007202=Reactome:REACT_12079, GO:0045944=PMID:19861239, GO:0040018=GO_REF:0000019, GO:0034138=Reactome:REACT_6783, GO:0005667=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0010033=PMID:8798441, GO:0042493=GO_REF:0000019, GO:0048015=Reactome:REACT_12464, GO:0005730=GO_REF:0000052, GO:0050821=GO_REF:0000024, GO:0003677=GO_REF:0000002, GO:0043565=GO_REF:0000019, GO:0007165=Reactome:REACT_12478, GO:0071363=GO_REF:0000019, GO:0007595=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0006468=PMID:8798441, GO:0034146=Reactome:REACT_9061} P16220 Cyclic AMP-responsive element-binding protein 1 protein 20111201 {GO:0005515=IPI, GO:0008361=IEA, GO:0000790=IEA, GO:0001190=IDA, GO:0003700=IDA, GO:0003705=IDA, GO:0007409=IEA, GO:0051403=TAS, GO:0046889=ISS, GO:0002756=TAS, GO:0010944=IDA, GO:0007173=TAS, GO:0007411=TAS, GO:0002755=TAS, GO:0046887=IEA, GO:0003712=TAS, GO:0001102=IPI, GO:0038124=TAS, GO:0038123=TAS, GO:0005719=IDA, GO:0034134=TAS, GO:0002224=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0045600=ISS, GO:0000980=IDA, GO:0005654=TAS, GO:0034166=TAS, GO:0035666=TAS, GO:0045893=ISS, GO:0034162=TAS, GO:0034142=TAS, GO:0035497=IDA, GO:0021983=IEA, GO:0007268=TAS, GO:0005634=IDA, GO:0007202=TAS, GO:0045944=IDA, GO:0040018=IEA, GO:0034138=TAS, GO:0005667=IEA, GO:0048011=TAS, GO:0010033=IDA, GO:0042493=IEA, GO:0048015=TAS, GO:0005730=IDA, GO:0050821=ISS, GO:0003677=IEA, GO:0043565=IEA, GO:0007165=TAS, GO:0071363=IEA, GO:0007595=IEA, GO:0019048=IEA, GO:0006468=IDA, GO:0034146=TAS} MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, activation of phospholipase C activity, axon guidance, axonogenesis, cellular response to growth factor stimulus, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, lactation, negative regulation of transcription by competitive promoter binding, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, pituitary gland development, positive regulation of fat cell differentiation, positive regulation of hormone secretion, positive regulation of lipid biosynthetic process, positive regulation of multicellular organism growth, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein phosphorylation, protein stabilization, regulation of cell size, response to drug, response to organic substance, signal transduction, stress-activated MAPK cascade, synaptic transmission, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, virus-host interaction nuclear chromatin, nuclear euchromatin, nucleolus, nucleoplasm, nucleus, transcription factor complex DNA binding, RNA polymerase II activating transcription factor binding, RNA polymerase II distal enhancer sequence-specific DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription, cAMP response element binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription cofactor activity Human CREB3 IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0043565=GO_REF:0000019, GO:0006986=GO_REF:0000037, GO:0003700=GO_REF:0000002, GO:0006935=GO_REF:0000037, GO:0045944=PMID:98051186, GO:0019048=GO_REF:0000037, GO:0005789=GO_REF:0000039, GO:0005634=PMID:20546900, GO:0090026=PMID:17296613, GO:0016021=GO_REF:0000037, GO:0006351=GO_REF:0000037} O43889 Cyclic AMP-responsive element-binding protein 3 protein 20130415 {GO:0005515=IPI, GO:0043565=IEA, GO:0006986=IEA, GO:0003700=IEA, GO:0006935=IEA, GO:0045944=IDA, GO:0019048=IEA, GO:0005789=IEA, GO:0005634=IDA, GO:0090026=IDA, GO:0016021=IEA, GO:0006351=IEA} chemotaxis, positive regulation of monocyte chemotaxis, positive regulation of transcription from RNA polymerase II promoter, response to unfolded protein, transcription, DNA-dependent, virus-host interaction endoplasmic reticulum membrane, integral to membrane, nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:P05412 CREB3L1 UniProtKB UniProtKB {GO:0006986=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0030500=GO_REF:0000019, GO:0001077=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0005783=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q96BA8 Cyclic AMP-responsive element-binding protein 3-like protein 1 protein 20130413 {GO:0006986=IEA, GO:0043565=IEA, GO:0030500=IEA, GO:0001077=IEA, GO:0003700=IEA, GO:0005783=IEA, GO:0003682=IEA, GO:0005789=IEA, GO:0005634=IEA, GO:0016021=IEA} regulation of bone mineralization, response to unfolded protein endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, chromatin binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0097 CREB3L2 UniProtKB UniProtKB {GO:0006986=GO_REF:0000037, GO:0034976=PMID:17178827, GO:0003700=GO_REF:0000002, GO:0044212=PMID:17178827, GO:0051216=GO_REF:0000024, GO:0035497=PMID:17178827, GO:0005783=PMID:17178827, GO:0005634=PMID:17178827, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0006888=GO_REF:0000019, GO:0002062=GO_REF:0000024, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0045893=PMID:17178827} Q70SY1 Cyclic AMP-responsive element-binding protein 3-like protein 2 protein 20100504 {GO:0006986=IEA, GO:0034976=IEP, GO:0003700=IEA, GO:0044212=IMP, GO:0051216=ISS, GO:0035497=IMP, GO:0005783=IDA, GO:0005634=IDA, GO:0006351=IEA, GO:0043565=IEA, GO:0006888=IEA, GO:0002062=ISS, GO:0005789=IEA, GO:0016021=IEA, GO:0045893=IDA} ER to Golgi vesicle-mediated transport, cartilage development, chondrocyte differentiation, positive regulation of transcription, DNA-dependent, response to endoplasmic reticulum stress, response to unfolded protein, transcription, DNA-dependent endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, nucleus cAMP response element binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding Human UniProtKB:Q8BH52 CREB3L3 InterPro UniProtKB {GO:0005515=PMID:16469704, GO:0006986=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0003700=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0016021=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9Y4A3 R33590_1 protein 20130413 {GO:0005515=IPI, GO:0006986=IEA, GO:0043565=IEA, GO:0005737=IDA, GO:0003700=IEA, GO:0005789=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0016021=IEA, GO:0006351=IEA} response to unfolded protein, transcription, DNA-dependent cytoplasm, endoplasmic reticulum membrane, integral to membrane, nucleolus, nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human InterPro:IPR004827 CREB3L4 UniProtKB UniProtKB {GO:0006986=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0000139=GO_REF:0000039, GO:0005783=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0007283=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q8TEY5 Cyclic AMP-responsive element-binding protein 3-like protein 4 protein 20130413 {GO:0006986=IEA, GO:0043565=IEA, GO:0003700=IEA, GO:0000139=IEA, GO:0005783=IEA, GO:0045944=IEA, GO:0005789=IEA, GO:0005634=IEA, GO:0016021=IEA, GO:0007283=IEA, GO:0006351=IEA} positive regulation of transcription from RNA polymerase II promoter, response to unfolded protein, spermatogenesis, transcription, DNA-dependent Golgi membrane, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0097 CREB5 PINC UniProtKB {GO:0005515=PMID:8440710, GO:0043565=GO_REF:0000002, GO:0001077=GO_REF:0000019, GO:0003700=PMID:8378084, GO:0006366=PMID:8378084, GO:0045444=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005634=PMID:8378084, GO:0045893=PMID:8378084, GO:0003676=GO_REF:0000002, GO:0060612=GO_REF:0000019} Q02930 Cyclic AMP-responsive element-binding protein 5 protein 20030904 {GO:0005515=IPI, GO:0043565=IEA, GO:0001077=IEA, GO:0003700=IDA, GO:0006366=TAS, GO:0045444=IEA, GO:0008270=IEA, GO:0005634=IC, GO:0045893=IDA, GO:0003676=IEA, GO:0060612=IEA} adipose tissue development, fat cell differentiation, positive regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, nucleic acid binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human CREBBP BHF-UCL UniProtKB {GO:0005515=PMID:16043483, GO:0001191=PMID:21539536, GO:0000987=PMID:21539536, GO:0010467=Reactome:REACT_71, GO:0000790=PMID:21539536, GO:0003700=PMID:7913207, GO:0006367=Reactome:REACT_14835, GO:0018076=PMID:12435739, GO:0007219=Reactome:REACT_118859, GO:0000123=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0003712=GO_REF:0000002, GO:0001102=PMID:11001584, GO:0001105=PMID:11001584, GO:0003713=PMID:12169688, GO:0033554=Reactome:REACT_120956, GO:0000122=PMID:21539536, GO:0045087=Reactome:REACT_6802, GO:0016407=PMID:11742995, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_160309, GO:0045893=PMID:11742995, GO:0042733=PMID:11001584, GO:0008134=PMID:15509593, GO:0061418=Reactome:REACT_120815, GO:0005634=PMID:12169688, GO:0044281=Reactome:REACT_111217, GO:0002039=PMID:9194565, GO:0005737=PMID:12929931, GO:0045944=GO_REF:0000019, GO:0001085=PMID:21539536, GO:0004871=PMID:8028671, GO:0030718=GO_REF:0000019, GO:0004402=PMID:11742995, GO:0001666=PMID:15261140, GO:0005667=GO_REF:0000019, GO:0006355=PMID:12169688, GO:0016573=PMID:11742995, GO:0043426=PMID:8621548, GO:0071456=Reactome:REACT_121311, GO:0042592=PMID:15261140, GO:0003677=GO_REF:0000019, GO:0007165=PMID:15261140, GO:0016604=PMID:15488321, GO:0001078=PMID:21539536, GO:0000940=GO_REF:0000019, GO:0006461=PMID:7913207, GO:0008589=PMID:11001584, GO:0019048=GO_REF:0000037, GO:0003682=GO_REF:0000019} Q92793 CREB-binding protein protein 20111118 {GO:0005515=IPI, GO:0001191=IDA, GO:0000987=IDA, GO:0010467=TAS, GO:0000790=IDA, GO:0003700=TAS, GO:0006367=TAS, GO:0018076=IDA, GO:0007219=TAS, GO:0000123=IEA, GO:0044255=TAS, GO:0003712=IEA, GO:0001102=TAS, GO:0001105=TAS, GO:0003713=IDA, GO:0033554=TAS, GO:0000122=IDA, GO:0045087=TAS, GO:0016407=IDA, GO:0008270=IEA, GO:0005654=TAS, GO:0045893=IDA, GO:0042733=TAS, GO:0008134=IPI, GO:0061418=TAS, GO:0005634=IC, GO:0044281=TAS, GO:0002039=IPI, GO:0005737=IDA, GO:0045944=IEA, GO:0001085=IPI, GO:0004871=TAS, GO:0030718=IEA, GO:0004402=IDA, GO:0001666=TAS, GO:0005667=IEA, GO:0006355=IDA, GO:0016573=IDA, GO:0043426=IDA, GO:0071456=TAS, GO:0042592=NAS, GO:0003677=IEA, GO:0007165=NAS, GO:0016604=IDA, GO:0001078=IDA, GO:0000940=IEA, GO:0006461=TAS, GO:0008589=TAS, GO:0019048=IEA, GO:0003682=IEA} N-terminal peptidyl-lysine acetylation, Notch signaling pathway, cellular lipid metabolic process, cellular response to hypoxia, cellular response to stress, embryonic digit morphogenesis, gene expression, germ-line stem cell maintenance, histone acetylation, homeostatic process, innate immune response, negative regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein complex assembly, regulation of smoothened signaling pathway, regulation of transcription from RNA polymerase II promoter in response to hypoxia, regulation of transcription, DNA-dependent, response to hypoxia, signal transduction, small molecule metabolic process, transcription initiation from RNA polymerase II promoter, virus-host interaction condensed chromosome outer kinetochore, cytoplasm, histone acetyltransferase complex, nuclear body, nuclear chromatin, nucleoplasm, nucleus, transcription factor complex DNA binding, MRF binding, RNA polymerase II activating transcription factor binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, RNA polymerase II transcription coactivator activity, RNA polymerase II transcription factor binding, RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription, acetyltransferase activity, chromatin binding, core promoter proximal region sequence-specific DNA binding, histone acetyltransferase activity, p53 binding, protein binding, sequence-specific DNA binding transcription factor activity, signal transducer activity, transcription coactivator activity, transcription cofactor activity, transcription factor binding, zinc ion binding Human CREBL2 UniProtKB UniProtKB {GO:0003700=GO_REF:0000002, GO:0050821=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0007165=PMID:9693048, GO:0046889=GO_REF:0000024, GO:0007049=GO_REF:0000037, GO:0033138=GO_REF:0000024, GO:0046326=GO_REF:0000024, GO:0045600=GO_REF:0000024, GO:0045893=GO_REF:0000024} O60519 cAMP-responsive element-binding protein-like 2 protein 20111216 {GO:0003700=IEA, GO:0050821=ISS, GO:0005634=ISS, GO:0006351=IEA, GO:0030154=IEA, GO:0043565=IEA, GO:0007165=TAS, GO:0046889=ISS, GO:0007049=IEA, GO:0033138=ISS, GO:0046326=ISS, GO:0045600=ISS, GO:0045893=ISS} cell cycle, cell differentiation, positive regulation of fat cell differentiation, positive regulation of glucose import, positive regulation of lipid biosynthetic process, positive regulation of peptidyl-serine phosphorylation, positive regulation of transcription, DNA-dependent, protein stabilization, signal transduction, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:Q32M00 CREBZF IntAct UniProtKB {GO:0005515=PMID:19690166, GO:0043565=GO_REF:0000002, GO:0051090=PMID:15705566, GO:0003700=GO_REF:0000002, GO:0045814=PMID:15705566, GO:0005634=PMID:15705566, GO:0009615=PMID:10871379, GO:0003677=PMID:10871379, GO:0045892=PMID:15705566, GO:0006351=PMID:10871379} Q9NS37 CREB/ATF bZIP transcription factor protein 20130415 {GO:0005515=IPI, GO:0043565=IEA, GO:0051090=IDA, GO:0003700=IEA, GO:0045814=IEP, GO:0005634=IDA, GO:0009615=IDA, GO:0003677=NAS, GO:0045892=IMP, GO:0006351=IDA} negative regulation of gene expression, epigenetic, negative regulation of transcription, DNA-dependent, regulation of sequence-specific DNA binding transcription factor activity, response to virus, transcription, DNA-dependent nucleus DNA binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:Q96EB6 CREG1 PINC UniProtKB {GO:0005667=GO_REF:0000019, GO:0006357=PMID:9710587, GO:0008283=PMID:9710587, GO:0003714=PMID:9710587, GO:0010181=GO_REF:0000002, GO:0016491=GO_REF:0000002, GO:0007275=PMID:9710587, GO:0005576=GO_REF:0000039, GO:0040008=GO_REF:0000037, GO:0008134=GO_REF:0000019} O75629 Protein CREG1 protein 20030904 {GO:0005667=IEA, GO:0006357=TAS, GO:0008283=TAS, GO:0003714=TAS, GO:0010181=IEA, GO:0016491=IEA, GO:0007275=TAS, GO:0005576=IEA, GO:0040008=IEA, GO:0008134=IEA} cell proliferation, multicellular organismal development, regulation of growth, regulation of transcription from RNA polymerase II promoter extracellular region, transcription factor complex FMN binding, oxidoreductase activity, transcription corepressor activity, transcription factor binding Human CRELD1 BHF-UCL UniProtKB {GO:0003279=PMID:18076106, GO:0003197=PMID:18076106, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q96HD1 Cysteine-rich with EGF-like domain protein 1 protein 20100520 {GO:0003279=TAS, GO:0003197=TAS, GO:0005509=IEA, GO:0016021=IEA} cardiac septum development, endocardial cushion development integral to membrane calcium ion binding Human CRELD2 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0005794=GO_REF:0000019, GO:0005783=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0005615=GO_REF:0000019} Q6UXH1 Cysteine-rich with EGF-like domain protein 2 protein 20130415 {GO:0005515=IPI, GO:0005794=IEA, GO:0005783=IEA, GO:0005509=IEA, GO:0005615=IEA} Golgi apparatus, endoplasmic reticulum, extracellular space calcium ion binding, protein binding Human UniProtKB:P42771 CREM InterPro UniProtKB {GO:0005667=GO_REF:0000019, GO:0006355=PMID:8206879, GO:0003700=GO_REF:0000002, GO:0006687=GO_REF:0000019, GO:0005634=GO_REF:0000002, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0003677=PMID:7916662, GO:0006351=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0007165=PMID:7916662, GO:0008140=PMID:8206879, GO:0045944=GO_REF:0000019} Q5W1A7 cAMP responsive element modulator, isoform CRA_b protein 20130413 {GO:0005667=IEA, GO:0006355=IDA, GO:0003700=IEA, GO:0006687=IEA, GO:0005634=IEA, GO:0007275=IEA, GO:0007283=IEA, GO:0003677=NAS, GO:0006351=IEA, GO:0030154=IEA, GO:0043565=IEA, GO:0007165=TAS, GO:0008140=NAS, GO:0045944=IEA} cell differentiation, glycosphingolipid metabolic process, multicellular organismal development, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, signal transduction, spermatogenesis, transcription, DNA-dependent nucleus, transcription factor complex DNA binding, cAMP response element binding protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human InterPro:IPR004827 CRH BHF-UCL UniProtKB {GO:0005515=PMID:18801728, GO:0043627=GO_REF:0000019, GO:0032811=GO_REF:0000019, GO:0033685=GO_REF:0000019, GO:0006704=GO_REF:0000019, GO:2000310=PMID:12895416, GO:2000854=GO_REF:0000019, GO:0005615=PMID:18559919, GO:0007611=PMID:7477348, GO:0060548=GO_REF:0000019, GO:0005184=PMID:7867564, GO:0010942=GO_REF:0000019, GO:0035641=GO_REF:0000019, GO:0008306=GO_REF:0000019, GO:0014062=GO_REF:0000019, GO:0051412=GO_REF:0000019, GO:0007565=PMID:18559919, GO:0007567=PMID:7585095, GO:0007616=GO_REF:0000019, GO:0050801=GO_REF:0000019, GO:0071314=GO_REF:0000019, GO:0010841=PMID:18329818, GO:0010700=GO_REF:0000019, GO:0033494=GO_REF:0000019, GO:0005179=PMID:7585095, GO:0016101=GO_REF:0000019, GO:0007631=GO_REF:0000019, GO:0045472=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0030325=GO_REF:0000019, GO:0030324=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0030819=GO_REF:0000019, GO:0007268=PMID:7477348, GO:0045776=GO_REF:0000019, GO:0090280=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0006954=PMID:18559919, GO:0043196=GO_REF:0000019, GO:0001963=PMID:12895416, GO:0043204=GO_REF:0000019, GO:0060456=GO_REF:0000019, GO:0051461=GO_REF:0000019, GO:2000987=GO_REF:0000019, GO:0051464=PMID:18329818, GO:0070093=GO_REF:0000019, GO:0035902=GO_REF:0000019, GO:0051430=GO_REF:0000019, GO:0035774=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0051431=GO_REF:0000019, GO:0005102=PMID:7477348, GO:0005576=Reactome:REACT_22268, GO:0021854=GO_REF:0000019, GO:0010628=GO_REF:0000019, GO:0007165=PMID:7867564, GO:0042322=PMID:18329818, GO:0010629=GO_REF:0000019, GO:0001934=GO_REF:0000019, GO:0048265=GO_REF:0000019, GO:0008628=GO_REF:0000019, GO:0017045=GO_REF:0000019, GO:0071549=GO_REF:0000019} P06850 Corticoliberin protein 20090114 {GO:0005515=IPI, GO:0043627=IEA, GO:0032811=IEA, GO:0033685=IEA, GO:0006704=IEA, GO:2000310=IDA, GO:2000854=IEA, GO:0005615=IDA, GO:0007611=TAS, GO:0060548=IEA, GO:0005184=TAS, GO:0010942=IEA, GO:0035641=IEA, GO:0008306=IEA, GO:0014062=IEA, GO:0051412=IEA, GO:0007565=IDA, GO:0007567=TAS, GO:0007616=IEA, GO:0050801=IEA, GO:0071314=IEA, GO:0010841=NAS, GO:0010700=IEA, GO:0033494=IEA, GO:0005179=TAS, GO:0016101=IEA, GO:0007631=IEA, GO:0045472=IEA, GO:0008284=IEA, GO:0030325=IEA, GO:0030324=IEA, GO:0045471=IEA, GO:0030819=IEA, GO:0007268=TAS, GO:0045776=IEA, GO:0090280=IEA, GO:0005737=IEA, GO:0006954=IDA, GO:0043196=IEA, GO:0001963=IDA, GO:0043204=IEA, GO:0060456=IEA, GO:0051461=IEA, GO:2000987=IEA, GO:0051464=IDA, GO:0070093=IEA, GO:0035902=IEA, GO:0051430=IEA, GO:0035774=IEA, GO:0042493=IEA, GO:0051431=IEA, GO:0005102=TAS, GO:0005576=TAS, GO:0021854=IEA, GO:0010628=IEA, GO:0007165=TAS, GO:0042322=NAS, GO:0010629=IEA, GO:0001934=IEA, GO:0048265=IEA, GO:0008628=IEA, GO:0017045=IEA, GO:0071549=IEA} adrenal gland development, associative learning, cellular response to cocaine, cellular response to dexamethasone stimulus, diterpenoid metabolic process, feeding behavior, female pregnancy, ferulate metabolic process, glucocorticoid biosynthetic process, hormone-mediated apoptotic signaling pathway, hypothalamus development, inflammatory response, ion homeostasis, learning or memory, locomotory exploration behavior, long-term memory, lung development, negative regulation of blood pressure, negative regulation of cell death, negative regulation of circadian sleep/wake cycle, REM sleep, negative regulation of epinephrine secretion, negative regulation of gene expression, negative regulation of glucagon secretion, negative regulation of luteinizing hormone secretion, negative regulation of norepinephrine secretion, parturition, positive regulation of behavioral fear response, positive regulation of cAMP biosynthetic process, positive regulation of calcium ion import, positive regulation of cell death, positive regulation of cell proliferation, positive regulation of circadian sleep/wake cycle, wakefulness, positive regulation of corticosterone secretion, positive regulation of corticotropin secretion, positive regulation of cortisol secretion, positive regulation of digestive system process, positive regulation of gene expression, positive regulation of insulin secretion involved in cellular response to glucose stimulus, positive regulation of protein phosphorylation, regulation of N-methyl-D-aspartate selective glutamate receptor activity, regulation of serotonin secretion, response to corticosterone stimulus, response to drug, response to estrogen stimulus, response to ethanol, response to ether, response to immobilization stress, response to pain, signal transduction, synaptic transmission, synaptic transmission, dopaminergic cytoplasm, extracellular region, extracellular space, perikaryon, varicosity corticotropin-releasing hormone activity, corticotropin-releasing hormone receptor 1 binding, corticotropin-releasing hormone receptor 2 binding, hormone activity, neuropeptide hormone activity, protein binding, receptor binding Human CRHBP UniProtKB UniProtKB {GO:0005515=PMID:18234674, GO:0005783=PMID:21624661, GO:0051424=PMID:1846945, GO:2000310=GO_REF:0000024, GO:0031045=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0005615=PMID:18559919, GO:0030425=GO_REF:0000024, GO:0005622=GO_REF:0000024, GO:0045055=PMID:21624661, GO:0035865=PMID:21624661, GO:0006954=PMID:18559919, GO:0071392=PMID:15345745, GO:0001963=GO_REF:0000024, GO:0043196=GO_REF:0000024, GO:0071356=PMID:15345745, GO:0007611=PMID:7477348, GO:0071277=GO_REF:0000024, GO:0007610=GO_REF:0000024, GO:0043204=GO_REF:0000024, GO:0043679=GO_REF:0000024, GO:0030141=PMID:21624661, GO:0042277=GO_REF:0000024, GO:0007565=PMID:18559919, GO:0005794=PMID:21624661, GO:0005771=GO_REF:0000024, GO:0005874=GO_REF:0000024, GO:0071314=GO_REF:0000024, GO:0071391=PMID:15345745, GO:0033554=PMID:21039637, GO:0035690=GO_REF:0000024, GO:0097211=GO_REF:0000024, GO:0002125=GO_REF:0000024, GO:0007165=PMID:7477348, GO:0009755=PMID:18234674, GO:0048149=PMID:21039637, GO:0050795=PMID:21039637, GO:0051459=PMID:13150566, GO:0042445=GO_REF:0000019, GO:0005767=GO_REF:0000024, GO:0071320=GO_REF:0000024} P24387 Corticotropin-releasing factor-binding protein protein 20120111 {GO:0005515=IPI, GO:0005783=IDA, GO:0051424=IDA, GO:2000310=ISS, GO:0031045=ISS, GO:0005634=ISS, GO:0005615=IDA, GO:0030425=ISS, GO:0005622=ISS, GO:0045055=IDA, GO:0035865=IDA, GO:0006954=IDA, GO:0071392=IDA, GO:0001963=ISS, GO:0043196=ISS, GO:0071356=IDA, GO:0007611=TAS, GO:0071277=ISS, GO:0007610=ISS, GO:0043204=ISS, GO:0043679=ISS, GO:0030141=IDA, GO:0042277=ISS, GO:0007565=IDA, GO:0005794=IDA, GO:0005771=ISS, GO:0005874=ISS, GO:0071314=ISS, GO:0071391=IDA, GO:0033554=IMP, GO:0035690=ISS, GO:0097211=ISS, GO:0002125=ISS, GO:0007165=TAS, GO:0009755=IDA, GO:0048149=IMP, GO:0050795=IMP, GO:0051459=IDA, GO:0042445=IEA, GO:0005767=ISS, GO:0071320=ISS} behavior, behavioral response to ethanol, cellular response to cAMP, cellular response to calcium ion, cellular response to cocaine, cellular response to drug, cellular response to estradiol stimulus, cellular response to estrogen stimulus, cellular response to gonadotropin-releasing hormone, cellular response to potassium ion, cellular response to stress, cellular response to tumor necrosis factor, female pregnancy, hormone metabolic process, hormone-mediated signaling pathway, inflammatory response, learning or memory, maternal aggressive behavior, regulated secretory pathway, regulation of N-methyl-D-aspartate selective glutamate receptor activity, regulation of behavior, regulation of corticotropin secretion, signal transduction, synaptic transmission, dopaminergic Golgi apparatus, axon terminus, dendrite, dense core granule, endoplasmic reticulum, extracellular space, intracellular, microtubule, multivesicular body, nucleus, perikaryon, secondary lysosome, secretory granule, varicosity corticotropin-releasing hormone binding, peptide binding, protein binding Human UniProtKB:Q60571 CRHR1 IntAct UniProtKB {GO:0005515=PMID:18801728, GO:0005802=GO_REF:0000019, GO:0015056=GO_REF:0000019, GO:0005886=Reactome:REACT_22268, GO:0032811=GO_REF:0000019, GO:0051424=GO_REF:0000019, GO:0032099=GO_REF:0000019, GO:0048148=GO_REF:0000019, GO:0007200=GO_REF:0000019, GO:0060291=GO_REF:0000019, GO:0007204=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0007190=PMID:10598591, GO:0001965=GO_REF:0000019, GO:0006955=PMID:7692441, GO:0007218=GO_REF:0000019, GO:0030855=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0007613=GO_REF:0000019, GO:0043404=GO_REF:0000019, GO:0035641=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0035902=GO_REF:0000019, GO:0007565=PMID:7585095, GO:0007567=PMID:10598591, GO:0004930=GO_REF:0000002, GO:0005771=GO_REF:0000019, GO:1901215=GO_REF:0000019, GO:0045177=GO_REF:0000019, GO:0021854=GO_REF:0000019, GO:0031982=GO_REF:0000019, GO:0043306=GO_REF:0000019, GO:0033267=GO_REF:0000019, GO:0007186=PMID:8243652, GO:0016020=GO_REF:0000002, GO:0005887=PMID:10598591, GO:0008542=GO_REF:0000019, GO:0007188=PMID:7692441, GO:0042755=GO_REF:0000019, GO:0007189=GO_REF:0000019, GO:0016021=GO_REF:0000002, GO:0048266=GO_REF:0000019} P34998 Corticotropin-releasing factor receptor 1 protein 20130415 {GO:0005515=IPI, GO:0005802=IEA, GO:0015056=IEA, GO:0005886=TAS, GO:0032811=IEA, GO:0051424=IEA, GO:0032099=IEA, GO:0048148=IEA, GO:0007200=IEA, GO:0060291=IEA, GO:0007204=IEA, GO:0032403=IEA, GO:0030425=IEA, GO:0007190=TAS, GO:0001965=IEA, GO:0006955=TAS, GO:0007218=IEA, GO:0030855=IEA, GO:0043025=IEA, GO:0007613=IEA, GO:0043404=IEA, GO:0035641=IEA, GO:0001666=IEA, GO:0035902=IEA, GO:0007565=NAS, GO:0007567=TAS, GO:0004930=IEA, GO:0005771=IEA, GO:1901215=IEA, GO:0045177=IEA, GO:0021854=IEA, GO:0031982=IEA, GO:0043306=IEA, GO:0033267=IEA, GO:0007186=TAS, GO:0016020=IEA, GO:0005887=TAS, GO:0008542=IEA, GO:0007188=TAS, GO:0042755=IEA, GO:0007189=IEA, GO:0016021=IEA, GO:0048266=IEA} G-protein coupled receptor signaling pathway, activation of adenylate cyclase activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, behavioral response to cocaine, behavioral response to pain, eating behavior, elevation of cytosolic calcium ion concentration, epithelial cell differentiation, female pregnancy, hypothalamus development, immune response, locomotory exploration behavior, long-term synaptic potentiation, memory, negative regulation of appetite, negative regulation of epinephrine secretion, negative regulation of neuron death, neuropeptide signaling pathway, parturition, phospholipase C-activating G-protein coupled receptor signaling pathway, positive regulation of mast cell degranulation, response to hypoxia, response to immobilization stress, visual learning apical part of cell, axon part, dendrite, integral to membrane, integral to plasma membrane, membrane, multivesicular body, neuronal cell body, plasma membrane, trans-Golgi network, vesicle G-protein alpha-subunit binding, G-protein coupled receptor activity, corticotrophin-releasing factor receptor activity, corticotropin-releasing hormone binding, corticotropin-releasing hormone receptor activity, protein binding, protein complex binding Human UniProtKB:P06850 CRHR2 Reactome UniProtKB {GO:0005515=PMID:11329063, GO:0015056=GO_REF:0000019, GO:0005794=GO_REF:0000019, GO:0005886=Reactome:REACT_22268, GO:0009986=GO_REF:0000019, GO:0004930=GO_REF:0000038, GO:0005783=GO_REF:0000019, GO:0005179=GO_REF:0000019, GO:0005887=PMID:8536644, GO:0016525=GO_REF:0000019, GO:0043950=GO_REF:0000019, GO:0007188=PMID:8536644, GO:0016021=GO_REF:0000038, GO:0043951=GO_REF:0000019} Q13324 Corticotropin-releasing factor receptor 2 protein 20090511 {GO:0005515=IPI, GO:0015056=IEA, GO:0005794=IEA, GO:0005886=TAS, GO:0009986=IEA, GO:0004930=IEA, GO:0005783=IEA, GO:0005179=IEA, GO:0005887=TAS, GO:0016525=IEA, GO:0043950=IEA, GO:0007188=TAS, GO:0016021=IEA, GO:0043951=IEA} adenylate cyclase-modulating G-protein coupled receptor signaling pathway, negative regulation of angiogenesis, negative regulation of cAMP-mediated signaling, positive regulation of cAMP-mediated signaling Golgi apparatus, cell surface, endoplasmic reticulum, integral to membrane, integral to plasma membrane, plasma membrane G-protein coupled receptor activity, corticotrophin-releasing factor receptor activity, hormone activity, protein binding Human CRIM1 GOC UniProtKB {GO:0005886=GO_REF:0000039, GO:0004867=GO_REF:0000002, GO:0005010=PMID:10642437, GO:0048009=PMID:10642437, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0001558=GO_REF:0000002, GO:0007399=PMID:10642437, GO:0005520=GO_REF:0000002} Q9NZV1 Cysteine-rich motor neuron 1 protein protein 20130413 {GO:0005886=IEA, GO:0004867=IEA, GO:0005010=TAS, GO:0048009=TAS, GO:0005576=IEA, GO:0016021=IEA, GO:0001558=IEA, GO:0007399=TAS, GO:0005520=IEA} insulin-like growth factor receptor signaling pathway, nervous system development, regulation of cell growth extracellular region, integral to membrane, plasma membrane insulin-like growth factor binding, insulin-like growth factor-activated receptor activity, serine-type endopeptidase inhibitor activity Human CRIP1 UniProtKB UniProtKB {GO:0010468=PMID:7999070, GO:0007507=PMID:7999070, GO:0042277=PMID:18670594, GO:0006955=PMID:20415737, GO:0003680=PMID:20108983, GO:0008301=PMID:20108983, GO:0008283=PMID:9126610, GO:0060741=PMID:9507743, GO:0008270=PMID:9126610, GO:0010043=PMID:7999070} P50238 Cysteine-rich protein 1 protein 20110822 {GO:0010468=IEP, GO:0007507=TAS, GO:0042277=IDA, GO:0006955=IEP, GO:0003680=IDA, GO:0008301=IDA, GO:0008283=TAS, GO:0060741=IEP, GO:0008270=IDA, GO:0010043=IDA} cell proliferation, heart development, immune response, prostate gland stromal morphogenesis, regulation of gene expression, response to zinc ion AT DNA binding, DNA binding, bending, peptide binding, zinc ion binding Human CRIP2 ENSEMBL UniProtKB {GO:0030097=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005938=GO_REF:0000019} P52943 Cysteine-rich protein 2 protein 20130413 {GO:0030097=IEA, GO:0008284=IEA, GO:0008270=IEA, GO:0005938=IEA} hemopoiesis, positive regulation of cell proliferation cell cortex zinc ion binding Human Ensembl:ENSMUSP00000081943 CRIPAK IntAct UniProtKB {GO:0005515=PMID:16278681, GO:0043627=PMID:16278681, GO:0005737=PMID:16278681, GO:0051493=PMID:16278681, GO:0005886=PMID:16278681, GO:0005783=PMID:16278681, GO:0005634=PMID:16278681, GO:0006469=PMID:16278681, GO:0033147=PMID:16278681} Q8N1N5 Cysteine-rich PAK1 inhibitor protein 20130415 {GO:0005515=IPI, GO:0043627=IDA, GO:0005737=IDA, GO:0051493=IDA, GO:0005886=IDA, GO:0005783=IDA, GO:0005634=IDA, GO:0006469=IDA, GO:0033147=IDA} negative regulation of intracellular estrogen receptor signaling pathway, negative regulation of protein kinase activity, regulation of cytoskeleton organization, response to estrogen stimulus cytoplasm, endoplasmic reticulum, nucleus, plasma membrane protein binding Human UniProtKB:Q13153 CRIPT UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0043198=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0014069=GO_REF:0000019, GO:0031122=GO_REF:0000019, GO:0030165=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0045184=GO_REF:0000019} Q9P021 Cysteine-rich PDZ-binding protein protein 20130413 {GO:0005737=IEA, GO:0030054=IEA, GO:0043198=IEA, GO:0043025=IEA, GO:0014069=IEA, GO:0031122=IEA, GO:0030165=IEA, GO:0032403=IEA, GO:0045184=IEA} cytoplasmic microtubule organization, establishment of protein localization cell junction, cytoplasm, dendritic shaft, neuronal cell body, postsynaptic density PDZ domain binding, protein complex binding Human UniProtKB-SubCell:SL-0086 CRISP3 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0045087=PMID:12223513, GO:0005578=PMID:12223513, GO:0042581=PMID:12223513, GO:0006952=PMID:12647793, GO:0005576=PMID:12009203} P54108 Cysteine-rich secretory protein 3 protein 20061026 {GO:0003674=ND, GO:0045087=NAS, GO:0005578=NAS, GO:0042581=IDA, GO:0006952=NAS, GO:0005576=IDA} defense response, innate immune response extracellular region, proteinaceous extracellular matrix, specific granule molecular_function Human CRISPLD2 LIFEdb UniProtKB {GO:0030133=GO_REF:0000054, GO:0031012=GO_REF:0000019, GO:0030198=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0008201=GO_REF:0000019} Q9H0B8 Cysteine-rich secretory protein LCCL domain-containing 2 protein 20100607 {GO:0030133=IDA, GO:0031012=IEA, GO:0030198=IEA, GO:0005576=IEA, GO:0008201=IEA} extracellular matrix organization extracellular matrix, extracellular region, transport vesicle heparin binding Human CRK IntAct UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005515=PMID:23275563, GO:0048011=Reactome:REACT_11061, GO:0035020=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0048013=PMID:11870224, GO:0006357=PMID:10748058, GO:0045309=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0005634=PMID:10748058, GO:0005829=Reactome:REACT_160134, GO:0000186=Reactome:REACT_12005, GO:0005737=PMID:11870224, GO:0046875=PMID:11870224, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0005070=GO_REF:0000019, GO:0032956=PMID:11870224, GO:0032319=PMID:11870224, GO:0038096=Reactome:REACT_160123, GO:0042169=PMID:9472046} P46108 Adapter molecule crk protein 20130415 {GO:0008286=TAS, GO:0005515=IPI, GO:0048011=TAS, GO:0035020=IEA, GO:0005886=IEA, GO:0048013=IDA, GO:0006357=TAS, GO:0045309=IEA, GO:0030168=TAS, GO:0005634=TAS, GO:0005829=TAS, GO:0000186=TAS, GO:0005737=IC, GO:0046875=IPI, GO:0007596=TAS, GO:0045087=TAS, GO:0005070=IEA, GO:0032956=IDA, GO:0032319=IDA, GO:0038096=TAS, GO:0042169=IPI} Fc-gamma receptor signaling pathway involved in phagocytosis, activation of MAPKK activity, blood coagulation, ephrin receptor signaling pathway, innate immune response, insulin receptor signaling pathway, neurotrophin TRK receptor signaling pathway, platelet activation, regulation of Rac protein signal transduction, regulation of Rho GTPase activity, regulation of actin cytoskeleton organization, regulation of transcription from RNA polymerase II promoter cytoplasm, cytosol, nucleus, plasma membrane SH2 domain binding, SH3/SH2 adaptor activity, ephrin receptor binding, protein binding, protein phosphorylated amino acid binding Human UniProtKB:P54253 CRKL IntAct UniProtKB {GO:0005515=PMID:16284401, GO:0048011=Reactome:REACT_11061, GO:0001568=GO_REF:0000019, GO:0007254=PMID:8798523, GO:0048538=GO_REF:0000019, GO:0007265=PMID:8798523, GO:0009952=GO_REF:0000019, GO:0005829=Reactome:REACT_23925, GO:0007507=GO_REF:0000019, GO:0035556=PMID:8361759, GO:0060017=GO_REF:0000019, GO:0000186=Reactome:REACT_12005, GO:0005070=PMID:8798523, GO:0009887=GO_REF:0000019, GO:0004871=PMID:8798523, GO:0005768=Reactome:REACT_12015} P46109 Crk-like protein protein 20130415 {GO:0005515=IPI, GO:0048011=TAS, GO:0001568=IEA, GO:0007254=TAS, GO:0048538=IEA, GO:0007265=TAS, GO:0009952=IEA, GO:0005829=TAS, GO:0007507=IEA, GO:0035556=TAS, GO:0060017=IEA, GO:0000186=TAS, GO:0005070=TAS, GO:0009887=IEA, GO:0004871=TAS, GO:0005768=TAS} JNK cascade, Ras protein signal transduction, activation of MAPKK activity, anterior/posterior pattern specification, blood vessel development, heart development, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, organ morphogenesis, parathyroid gland development, thymus development cytosol, endosome SH3/SH2 adaptor activity, protein binding, signal transducer activity Human UniProtKB:Q9EQG6 CRLF1 BHF-UCL UniProtKB {GO:0005515=PMID:10966616, GO:0001657=GO_REF:0000019, GO:0008284=PMID:10966616, GO:0005886=GO_REF:0000052, GO:0046982=PMID:10966616, GO:0042517=PMID:10966616, GO:2000672=GO_REF:0000019, GO:0005615=PMID:9686600, GO:0005125=PMID:10966616, GO:0097058=PMID:10966616, GO:0005127=PMID:10966616, GO:0043524=PMID:10966616, GO:0005737=GO_REF:0000052, GO:0019955=PMID:15034937, GO:0004872=PMID:9686600} O75462 Cytokine receptor-like factor 1 protein 20120404 {GO:0005515=IPI, GO:0001657=IEA, GO:0008284=IDA, GO:0005886=IDA, GO:0046982=IDA, GO:0042517=IDA, GO:2000672=IEA, GO:0005615=TAS, GO:0005125=IDA, GO:0097058=IDA, GO:0005127=IDA, GO:0043524=IDA, GO:0005737=IDA, GO:0019955=IPI, GO:0004872=TAS} negative regulation of motor neuron apoptotic process, negative regulation of neuron apoptotic process, positive regulation of cell proliferation, positive regulation of tyrosine phosphorylation of Stat3 protein, ureteric bud development CRLF-CLCF1 complex, cytoplasm, extracellular space, plasma membrane ciliary neurotrophic factor receptor binding, cytokine activity, cytokine binding, protein binding, protein heterodimerization activity, receptor activity Human CRLF2 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q9HC73 Cytokine receptor-like factor 2 protein 20130413 {GO:0005886=IEA, GO:0005576=IEA, GO:0016021=IEA} extracellular region, integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 CRLF3 UniProtKB UniProtKB {GO:0030308=PMID:19427400, GO:0005737=PMID:19427400, GO:0045944=PMID:19427400, GO:0045893=PMID:19427400, GO:0045749=PMID:19427400, GO:0071158=PMID:19427400, GO:0046427=PMID:19427400} Q8IUI8 Cytokine receptor-like factor 3 protein 20101115 {GO:0030308=IDA, GO:0005737=IDA, GO:0045944=IDA, GO:0045893=IDA, GO:0045749=IMP, GO:0071158=IDA, GO:0046427=IDA} negative regulation of S phase of mitotic cell cycle, negative regulation of cell growth, positive regulation of JAK-STAT cascade, positive regulation of cell cycle arrest, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent cytoplasm Human CRLS1 Reactome UniProtKB {GO:0016780=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0036148=Reactome:REACT_121324, GO:0005743=Reactome:REACT_121361, GO:0044281=Reactome:REACT_111217, GO:0032049=Reactome:REACT_120920, GO:0016021=GO_REF:0000037, GO:0008654=GO_REF:0000002, GO:0006644=Reactome:REACT_120870, GO:0046474=Reactome:REACT_121401} Q9UJA2 Cardiolipin synthase protein 20130301 {GO:0016780=IEA, GO:0016020=IEA, GO:0036148=TAS, GO:0005743=TAS, GO:0044281=TAS, GO:0032049=TAS, GO:0016021=IEA, GO:0008654=IEA, GO:0006644=TAS, GO:0046474=TAS} cardiolipin biosynthetic process, glycerophospholipid biosynthetic process, phosphatidylglycerol acyl-chain remodeling, phospholipid biosynthetic process, phospholipid metabolic process, small molecule metabolic process integral to membrane, membrane, mitochondrial inner membrane phosphotransferase activity, for other substituted phosphate groups Human CRMP1 HPA UniProtKB {GO:0005515=PMID:16169070, GO:0005815=GO_REF:0000039, GO:0016812=GO_REF:0000002, GO:0005819=GO_REF:0000039, GO:0030425=GO_REF:0000019, GO:0043231=GO_REF:0000052, GO:0007399=PMID:8973361, GO:0005829=Reactome:REACT_19321, GO:0005737=GO_REF:0000052, GO:0006139=PMID:8973361, GO:0007411=Reactome:REACT_18266, GO:0043025=GO_REF:0000019, GO:0006208=GO_REF:0000002} Q14194 Dihydropyrimidinase-related protein 1 protein 20110516 {GO:0005515=IPI, GO:0005815=IEA, GO:0016812=IEA, GO:0005819=IEA, GO:0030425=IEA, GO:0043231=IDA, GO:0007399=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0006139=TAS, GO:0007411=TAS, GO:0043025=IEA, GO:0006208=IEA} axon guidance, nervous system development, nucleobase-containing compound metabolic process, pyrimidine nucleobase catabolic process cytoplasm, cytosol, dendrite, intracellular membrane-bounded organelle, microtubule organizing center, neuronal cell body, spindle hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides, protein binding Human CRNKL1 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0000245=PMID:12084575, GO:0006396=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0016607=GO_REF:0000039, GO:0000398=PMID:11991638, GO:0003723=PMID:12084575, GO:0005681=PMID:11991638, GO:0071013=PMID:11991638} Q9BZJ0 Crooked neck-like protein 1 protein 20110302 {GO:0005622=IEA, GO:0000245=IDA, GO:0006396=IEA, GO:0005737=IEA, GO:0016607=IEA, GO:0000398=IC, GO:0003723=IDA, GO:0005681=IDA, GO:0071013=IDA} RNA processing, mRNA splicing, via spliceosome, spliceosomal complex assembly catalytic step 2 spliceosome, cytoplasm, intracellular, nuclear speck, spliceosomal complex RNA binding Human CRNN UniProtKB UniProtKB {GO:0005737=PMID:14967811, GO:0016337=PMID:2631556, GO:0009408=PMID:11606197, GO:0016020=PMID:2980212, GO:0005509=PMID:11056050} Q9UBG3 Cornulin protein 20040809 {GO:0005737=TAS, GO:0016337=IDA, GO:0009408=IDA, GO:0016020=IDA, GO:0005509=NAS} cell-cell adhesion, response to heat cytoplasm, membrane calcium ion binding Human CROCC HPA UniProtKB {GO:0005515=PMID:18086858, GO:0005813=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005814=GO_REF:0000024, GO:0015629=GO_REF:0000052, GO:0051297=PMID:16203858, GO:0005737=GO_REF:0000052, GO:0007049=GO_REF:0000037, GO:0008104=PMID:18086858, GO:0005198=GO_REF:0000024, GO:0035253=GO_REF:0000024, GO:0030030=GO_REF:0000037, GO:0019894=GO_REF:0000024} Q5TZA2 Rootletin protein 20101115 {GO:0005515=IPI, GO:0005813=IDA, GO:0005886=IDA, GO:0005814=ISS, GO:0015629=IDA, GO:0051297=IDA, GO:0005737=IDA, GO:0007049=IEA, GO:0008104=IMP, GO:0005198=ISS, GO:0035253=ISS, GO:0030030=IEA, GO:0019894=ISS} cell cycle, cell projection organization, centrosome organization, protein localization actin cytoskeleton, centriole, centrosome, ciliary rootlet, cytoplasm, plasma membrane kinesin binding, protein binding, structural molecule activity Human CROT HPA UniProtKB {GO:0016746=GO_REF:0000038, GO:0006635=PMID:21619872, GO:0005782=Reactome:REACT_16985, GO:0005102=PMID:20178365, GO:0044281=Reactome:REACT_111217, GO:0008458=PMID:21619872, GO:0006091=PMID:10486279, GO:0043231=GO_REF:0000052, GO:0005739=GO_REF:0000019, GO:0006810=GO_REF:0000037, GO:0006631=PMID:21619872, GO:0051791=PMID:10486279, GO:0033540=Reactome:REACT_17017, GO:0015908=GO_REF:0000019, GO:0044255=Reactome:REACT_16957, GO:0005777=PMID:10486279} Q9UKG9 Peroxisomal carnitine O-octanoyltransferase protein 20100326 {GO:0016746=IEA, GO:0006635=IDA, GO:0005782=TAS, GO:0005102=IPI, GO:0044281=TAS, GO:0008458=IDA, GO:0006091=IDA, GO:0043231=IDA, GO:0005739=IEA, GO:0006810=IEA, GO:0006631=IMP, GO:0051791=IDA, GO:0033540=TAS, GO:0015908=IEA, GO:0044255=TAS, GO:0005777=NAS} cellular lipid metabolic process, fatty acid beta-oxidation, fatty acid beta-oxidation using acyl-CoA oxidase, fatty acid metabolic process, fatty acid transport, generation of precursor metabolites and energy, medium-chain fatty acid metabolic process, small molecule metabolic process, transport intracellular membrane-bounded organelle, mitochondrion, peroxisomal matrix, peroxisome carnitine O-octanoyltransferase activity, receptor binding, transferase activity, transferring acyl groups Human CRP BHF-UCL UniProtKB {GO:0033265=PMID:2477488, GO:0005515=PMID:17785206, GO:0051258=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0030175=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0030426=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0006954=PMID:10408362, GO:0015485=GO_REF:0000019, GO:0006958=GO_REF:0000019, GO:0071277=GO_REF:0000019, GO:0071333=GO_REF:0000019, GO:0008228=PMID:2477488, GO:1900006=GO_REF:0000019, GO:0010288=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0010745=PMID:18322245, GO:0007568=GO_REF:0000019, GO:0030169=PMID:18322245, GO:0005576=PMID:14718574, GO:0006953=PMID:2477488, GO:0010888=PMID:18322245, GO:0051637=PMID:2477488, GO:0042060=GO_REF:0000019} P02741 C-reactive protein protein 20080707 {GO:0033265=TAS, GO:0005515=IPI, GO:0051258=IEA, GO:0005886=IEA, GO:0045471=IEA, GO:0030175=IEA, GO:0005615=IEA, GO:0042803=IEA, GO:0046872=IEA, GO:0030426=IEA, GO:0005739=IEA, GO:0006954=TAS, GO:0015485=IEA, GO:0006958=IEA, GO:0071277=IEA, GO:0071333=IEA, GO:0008228=TAS, GO:1900006=IEA, GO:0010288=IEA, GO:0001666=IEA, GO:0010745=IDA, GO:0007568=IEA, GO:0030169=IDA, GO:0005576=NAS, GO:0006953=TAS, GO:0010888=IDA, GO:0051637=TAS, GO:0042060=IEA} acute-phase response, aging, cellular response to calcium ion, cellular response to glucose stimulus, complement activation, classical pathway, inflammatory response, negative regulation of lipid storage, negative regulation of macrophage derived foam cell differentiation, opsonization, positive regulation of dendrite development, protein polymerization, response to ethanol, response to hypoxia, response to lead ion, wound healing extracellular region, extracellular space, filopodium, growth cone, mitochondrion, plasma membrane Gram-positive bacterial cell surface binding, cholesterol binding, choline binding, low-density lipoprotein particle binding, metal ion binding, protein binding, protein homodimerization activity Human CRTAM HGNC UniProtKB {GO:0008037=PMID:15811952, GO:0051606=PMID:15811952, GO:0005886=Reactome:REACT_11097, GO:0001913=PMID:15811952, GO:0045954=PMID:15811952, GO:0050776=Reactome:REACT_11152, GO:0005102=PMID:15811952, GO:0002860=PMID:15811952, GO:0002355=PMID:15811952, GO:0050798=PMID:15811952, GO:0050715=PMID:15811952, GO:0016021=GO_REF:0000037} O95727 Cytotoxic and regulatory T-cell molecule protein 20060628 {GO:0008037=IDA, GO:0051606=IDA, GO:0005886=TAS, GO:0001913=IDA, GO:0045954=IDA, GO:0050776=TAS, GO:0005102=IPI, GO:0002860=IDA, GO:0002355=IDA, GO:0050798=IDA, GO:0050715=IDA, GO:0016021=IEA} T cell mediated cytotoxicity, activated T cell proliferation, cell recognition, detection of stimulus, detection of tumor cell, positive regulation of cytokine secretion, positive regulation of natural killer cell mediated cytotoxicity, positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, regulation of immune response integral to membrane, plasma membrane receptor binding Human CRTAP Reactome UniProtKB {GO:0018400=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0005578=GO_REF:0000039, GO:0005788=Reactome:REACT_120939, GO:0007283=GO_REF:0000019} O75718 Cartilage-associated protein protein 20120416 {GO:0018400=IEA, GO:0030198=TAS, GO:0005578=IEA, GO:0005788=TAS, GO:0007283=IEA} extracellular matrix organization, peptidyl-proline hydroxylation to 3-hydroxy-L-proline, spermatogenesis endoplasmic reticulum lumen, proteinaceous extracellular matrix Human CRTC1 HPA UniProtKB {GO:0005515=PMID:14506290, GO:0032793=GO_REF:0000002, GO:0008140=PMID:14536081, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0051289=GO_REF:0000002, GO:0045944=PMID:14536081, GO:0019048=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037} Q6UUV9 CREB-regulated transcription coactivator 1 protein 20101115 {GO:0005515=IPI, GO:0032793=IEA, GO:0008140=IDA, GO:0005737=IDA, GO:0005886=IDA, GO:0051289=IEA, GO:0045944=IDA, GO:0019048=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006351=IEA} positive regulation of CREB transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, protein homotetramerization, transcription, DNA-dependent, virus-host interaction cytoplasm, nucleolus, nucleus, plasma membrane cAMP response element binding protein binding, protein binding Human CRTC2 HPA UniProtKB {GO:0032793=GO_REF:0000002, GO:0008140=GO_REF:0000002, GO:0005737=GO_REF:0000002, GO:0051289=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0006094=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0042593=GO_REF:0000024, GO:0006351=GO_REF:0000037} Q5T4K5 CREB-regulated transcription coactivator 2 protein 20111111 {GO:0032793=IEA, GO:0008140=IEA, GO:0005737=IEA, GO:0051289=IEA, GO:0019048=IEA, GO:0006094=ISS, GO:0005730=IDA, GO:0005634=IDA, GO:0042593=ISS, GO:0006351=IEA} gluconeogenesis, glucose homeostasis, positive regulation of CREB transcription factor activity, protein homotetramerization, transcription, DNA-dependent, virus-host interaction cytoplasm, nucleolus, nucleus cAMP response element binding protein binding NOT Human CRTC3 HPA UniProtKB {GO:0032793=GO_REF:0000002, GO:0008140=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0051289=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037} Q6UUV7 CREB-regulated transcription coactivator 3 protein 20110516 {GO:0032793=IEA, GO:0008140=IEA, GO:0005737=IDA, GO:0051289=IEA, GO:0019048=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006351=IEA} positive regulation of CREB transcription factor activity, protein homotetramerization, transcription, DNA-dependent, virus-host interaction cytoplasm, nucleolus, nucleus cAMP response element binding protein binding Human CRX PINC UniProtKB {GO:0005667=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0060041=GO_REF:0000019, GO:0005634=GO_REF:0000040, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0043522=PMID:10887186, GO:0003682=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0009887=PMID:9390563, GO:0007601=GO_REF:0000037, GO:0050896=GO_REF:0000037} O43186 Cone-rod homeobox protein protein 20031119 {GO:0005667=IEA, GO:0003700=IEA, GO:0060041=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0043565=IEA, GO:0043522=IPI, GO:0003682=IEA, GO:0045944=IEA, GO:0009887=TAS, GO:0007601=IEA, GO:0050896=IEA} organ morphogenesis, positive regulation of transcription from RNA polymerase II promoter, response to stimulus, retina development in camera-type eye, transcription, DNA-dependent, visual perception nucleus, transcription factor complex DNA binding, chromatin binding, leucine zipper domain binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human CRY1 BHF-UCL UniProtKB {GO:0005515=PMID:9383998, GO:0000988=PMID:15147242, GO:0003904=PMID:8909283, GO:0019901=GO_REF:0000019, GO:0019902=PMID:9383998, GO:0009785=PMID:8909283, GO:0005634=GO_REF:0000039, GO:0000122=PMID:15147242, GO:0003677=PMID:9801304, GO:0006351=GO_REF:0000037, GO:0003914=PMID:8909283, GO:0005739=GO_REF:0000019, GO:0018298=GO_REF:0000037, GO:0009882=PMID:8909283, GO:0003690=PMID:9801304, GO:0006281=GO_REF:0000002, GO:0000166=GO_REF:0000037, GO:0007623=GO_REF:0000019, GO:0042752=GO_REF:0000024} Q16526 Cryptochrome-1 protein 20111104 {GO:0005515=IPI, GO:0000988=IDA, GO:0003904=IDA, GO:0019901=IEA, GO:0019902=IPI, GO:0009785=NAS, GO:0005634=IEA, GO:0000122=IDA, GO:0003677=TAS, GO:0006351=IEA, GO:0003914=IDA, GO:0005739=IEA, GO:0018298=IEA, GO:0009882=NAS, GO:0003690=IDA, GO:0006281=IEA, GO:0000166=IEA, GO:0007623=IEA, GO:0042752=ISS} DNA repair, blue light signaling pathway, circadian rhythm, negative regulation of transcription from RNA polymerase II promoter, protein-chromophore linkage, regulation of circadian rhythm, transcription, DNA-dependent mitochondrion, nucleus DNA (6-4) photolyase activity, DNA binding, blue light photoreceptor activity, deoxyribodipyrimidine photo-lyase activity, double-stranded DNA binding, nucleotide binding, phosphatase binding, protein binding, protein binding transcription factor activity, protein kinase binding Human CRY2 HPA UniProtKB {GO:0005515=PMID:9383998, GO:0000988=PMID:15147242, GO:0003904=PMID:8909283, GO:0005634=GO_REF:0000052, GO:0006606=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0018298=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0009882=PMID:8909283, GO:0000166=GO_REF:0000037, GO:0003697=PMID:12627958, GO:2000118=PMID:9753616, GO:0019902=PMID:9383998, GO:0009785=PMID:8909283, GO:0005576=PMID:9753616, GO:0000122=PMID:15147242, GO:0003677=PMID:12627958, GO:0006351=GO_REF:0000037, GO:0003913=GO_REF:0000002, GO:0003914=PMID:8909283, GO:0003684=PMID:12627958, GO:0006281=GO_REF:0000002, GO:0042752=GO_REF:0000019, GO:0007623=GO_REF:0000024, GO:0000719=PMID:12627958} Q49AN0 Cryptochrome-2 protein 20111111 {GO:0005515=IPI, GO:0000988=IDA, GO:0003904=IDA, GO:0005634=IDA, GO:0006606=IEA, GO:0005739=IEA, GO:0018298=IEA, GO:0005737=IDA, GO:0009882=NAS, GO:0000166=IEA, GO:0003697=IDA, GO:2000118=IDA, GO:0019902=IPI, GO:0009785=NAS, GO:0005576=IDA, GO:0000122=IDA, GO:0003677=IDA, GO:0006351=IEA, GO:0003913=IEA, GO:0003914=IDA, GO:0003684=IDA, GO:0006281=IEA, GO:0042752=IEA, GO:0007623=ISS, GO:0000719=IDA} DNA repair, blue light signaling pathway, circadian rhythm, negative regulation of transcription from RNA polymerase II promoter, photoreactive repair, protein import into nucleus, protein-chromophore linkage, regulation of circadian rhythm, regulation of sodium-dependent phosphate transport, transcription, DNA-dependent cytoplasm, extracellular region, mitochondrion, nucleus DNA (6-4) photolyase activity, DNA binding, DNA photolyase activity, blue light photoreceptor activity, damaged DNA binding, deoxyribodipyrimidine photo-lyase activity, nucleotide binding, phosphatase binding, protein binding, protein binding transcription factor activity, single-stranded DNA binding Human CRYAA HGNC UniProtKB {GO:0005515=PMID:14752512, GO:0042542=GO_REF:0000019, GO:0005212=GO_REF:0000037, GO:0030307=GO_REF:0000019, GO:0005634=PMID:19464326, GO:0046872=GO_REF:0000037, GO:0048596=GO_REF:0000019, GO:0042802=GO_REF:0000019, GO:0042026=GO_REF:0000024, GO:0005737=PMID:14752512, GO:0007015=GO_REF:0000019, GO:0070309=GO_REF:0000019, GO:0051260=PMID:16303126, GO:0043154=GO_REF:0000019, GO:0010288=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0043066=PMID:14752512, GO:0032387=PMID:14752512, GO:0042493=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0060561=GO_REF:0000019, GO:0070141=GO_REF:0000019, GO:0007021=GO_REF:0000019, GO:0010629=GO_REF:0000019, GO:0001934=GO_REF:0000019, GO:0007005=GO_REF:0000019, GO:0051082=PMID:8943244, GO:0000072=GO_REF:0000019, GO:0007601=PMID:9467006} P02489 Alpha-crystallin A chain protein 20070313 {GO:0005515=IPI, GO:0042542=IEA, GO:0005212=IEA, GO:0030307=IEA, GO:0005634=IDA, GO:0046872=IEA, GO:0048596=IEA, GO:0042802=IEA, GO:0042026=ISS, GO:0005737=IDA, GO:0007015=IEA, GO:0070309=IEA, GO:0051260=IDA, GO:0043154=IEA, GO:0010288=IEA, GO:0001666=IEA, GO:0043066=IDA, GO:0032387=IDA, GO:0042493=IEA, GO:0051384=IEA, GO:0060561=IEA, GO:0070141=IEA, GO:0007021=IEA, GO:0010629=IEA, GO:0001934=IEA, GO:0007005=IEA, GO:0051082=IPI, GO:0000072=IEA, GO:0007601=IMP} M phase specific microtubule process, actin filament organization, apoptotic process involved in morphogenesis, embryonic camera-type eye morphogenesis, lens fiber cell morphogenesis, mitochondrion organization, negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of gene expression, negative regulation of intracellular transport, positive regulation of cell growth, positive regulation of protein phosphorylation, protein homooligomerization, protein refolding, response to UV-A, response to drug, response to glucocorticoid stimulus, response to hydrogen peroxide, response to hypoxia, response to lead ion, tubulin complex assembly, visual perception cytoplasm, nucleus identical protein binding, metal ion binding, protein binding, structural constituent of eye lens, unfolded protein binding Human CRYAB LIFEdb UniProtKB {GO:0005515=PMID:16225851, GO:0008017=GO_REF:0000019, GO:0042542=GO_REF:0000019, GO:0005212=GO_REF:0000037, GO:0030018=GO_REF:0000019, GO:0030308=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0005634=PMID:19464326, GO:0031109=GO_REF:0000019, GO:0032432=GO_REF:0000019, GO:0051403=GO_REF:0000019, GO:0042803=PMID:19646995, GO:0046872=GO_REF:0000037, GO:0005829=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0005737=GO_REF:0000054, GO:0006936=PMID:9731540, GO:0002088=GO_REF:0000019, GO:0006457=GO_REF:0000019, GO:0015630=GO_REF:0000019, GO:0006006=GO_REF:0000019, GO:0051260=PMID:16303126, GO:0043154=GO_REF:0000019, GO:0032355=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0043066=PMID:14752512, GO:0032387=PMID:14752512, GO:0005794=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0060561=GO_REF:0000019, GO:0007517=GO_REF:0000019, GO:0007021=GO_REF:0000019, GO:0010629=GO_REF:0000019, GO:0051082=PMID:16303126, GO:2000378=GO_REF:0000019} P02511 Alpha-crystallin B chain protein 20100607 {GO:0005515=IPI, GO:0008017=IEA, GO:0042542=IEA, GO:0005212=IEA, GO:0030018=IEA, GO:0030308=IEA, GO:0005886=IEA, GO:0005634=IDA, GO:0031109=IEA, GO:0032432=IEA, GO:0051403=IEA, GO:0042803=IPI, GO:0046872=IEA, GO:0005829=IEA, GO:0005739=IEA, GO:0005737=IDA, GO:0006936=TAS, GO:0002088=IEA, GO:0006457=IEA, GO:0015630=IEA, GO:0006006=IEA, GO:0051260=IDA, GO:0043154=IEA, GO:0032355=IEA, GO:0001666=IEA, GO:0043066=IDA, GO:0032387=IDA, GO:0005794=IEA, GO:0009986=IEA, GO:0007568=IEA, GO:0060561=IEA, GO:0007517=IEA, GO:0007021=IEA, GO:0010629=IEA, GO:0051082=IPI, GO:2000378=IEA} aging, apoptotic process involved in morphogenesis, glucose metabolic process, lens development in camera-type eye, microtubule polymerization or depolymerization, muscle contraction, muscle organ development, negative regulation of apoptotic process, negative regulation of cell growth, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of gene expression, negative regulation of intracellular transport, negative regulation of reactive oxygen species metabolic process, protein folding, protein homooligomerization, response to estradiol stimulus, response to hydrogen peroxide, response to hypoxia, stress-activated MAPK cascade, tubulin complex assembly Golgi apparatus, Z disc, actin filament bundle, cell surface, cytoplasm, cytosol, microtubule cytoskeleton, mitochondrion, nucleus, plasma membrane metal ion binding, microtubule binding, protein binding, protein homodimerization activity, structural constituent of eye lens, unfolded protein binding Human CRYBA1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000024, GO:0005212=GO_REF:0000037, GO:0002088=GO_REF:0000019, GO:0005634=GO_REF:0000024, GO:0007601=PMID:18587492, GO:0042803=GO_REF:0000019} P05813 Beta-crystallin A3 protein 20120713 {GO:0003674=ND, GO:0005737=ISS, GO:0005212=IEA, GO:0002088=IEA, GO:0005634=ISS, GO:0007601=IMP, GO:0042803=IEA} lens development in camera-type eye, visual perception cytoplasm, nucleus molecular_function, protein homodimerization activity, structural constituent of eye lens Human UniProtKB:P14881 CRYBA2 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005212=GO_REF:0000037, GO:0002088=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0042803=GO_REF:0000019} P53672 Beta-crystallin A2 protein 20090204 {GO:0008150=ND, GO:0003674=ND, GO:0005212=IEA, GO:0002088=IEA, GO:0005575=ND, GO:0042803=IEA} biological_process, lens development in camera-type eye cellular_component molecular_function, protein homodimerization activity, structural constituent of eye lens Human CRYBA4 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0005212=GO_REF:0000019, GO:0043010=PMID:16960806, GO:0005575=GO_REF:0000015, GO:0007601=PMID:16960806} P53673 Beta-crystallin A4 protein 20120720 {GO:0003674=ND, GO:0005212=IEA, GO:0043010=IMP, GO:0005575=ND, GO:0007601=IMP} camera-type eye development, visual perception cellular_component molecular_function, structural constituent of eye lens Human CRYBB1 PINC UniProtKB {GO:0005212=GO_REF:0000019, GO:0007601=PMID:8626774} P53674 Beta-crystallin B1 protein 20030904 {GO:0005212=IEA, GO:0007601=TAS} visual perception structural constituent of eye lens Human CRYBB2 IntAct UniProtKB {GO:0005212=GO_REF:0000019, GO:0005198=PMID:8224918, GO:0043010=GO_REF:0000019, GO:0007601=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0050896=GO_REF:0000037, GO:0042802=PMID:16319073} P43320 Beta-crystallin B2 protein 20130415 {GO:0005212=IEA, GO:0005198=NAS, GO:0043010=IEA, GO:0007601=IEA, GO:0042803=IEA, GO:0050896=IEA, GO:0042802=IPI} camera-type eye development, response to stimulus, visual perception identical protein binding, protein homodimerization activity, structural constituent of eye lens, structural molecule activity Human UniProtKB:P43320 CRYBB3 PINC UniProtKB {GO:0005212=GO_REF:0000019, GO:0007601=PMID:8999933} P26998 Beta-crystallin B3 protein 20030904 {GO:0005212=IEA, GO:0007601=TAS} visual perception structural constituent of eye lens Human CRYGC UniProtKB UniProtKB {GO:0005515=PMID:16303126, GO:0005212=PMID:12507494, GO:0005737=PMID:16303126, GO:0005634=PMID:16303126, GO:0043010=GO_REF:0000019, GO:0007601=PMID:18618005} P07315 Gamma-crystallin C protein 20090204 {GO:0005515=IPI, GO:0005212=NAS, GO:0005737=IDA, GO:0005634=IDA, GO:0043010=IEA, GO:0007601=IMP} camera-type eye development, visual perception cytoplasm, nucleus protein binding, structural constituent of eye lens Human CRYGD UniProtKB UniProtKB {GO:0005515=PMID:8943244, GO:0005737=GO_REF:0000024, GO:0005212=PMID:12507494, GO:0070306=GO_REF:0000024, GO:0002088=GO_REF:0000024, GO:0034614=PMID:8943244, GO:0005634=GO_REF:0000024, GO:0007601=PMID:9927684} P07320 Gamma-crystallin D protein 20120713 {GO:0005515=IPI, GO:0005737=ISS, GO:0005212=NAS, GO:0070306=ISS, GO:0002088=ISS, GO:0034614=IDA, GO:0005634=ISS, GO:0007601=IMP} cellular response to reactive oxygen species, lens development in camera-type eye, lens fiber cell differentiation, visual perception cytoplasm, nucleus protein binding, structural constituent of eye lens Human UniProtKB:P04342 CRYGS ENSEMBL UniProtKB {GO:0005212=GO_REF:0000019, GO:0002088=GO_REF:0000019, GO:0002009=GO_REF:0000019} P22914 Beta-crystallin S protein 20130413 {GO:0005212=IEA, GO:0002088=IEA, GO:0002009=IEA} lens development in camera-type eye, morphogenesis of an epithelium structural constituent of eye lens Human Ensembl:ENSMUSP00000043588 CRYL1 UniProtKB UniProtKB {GO:0050104=PMID:15809331, GO:0006631=GO_REF:0000002, GO:0070403=PMID:15809331, GO:0003857=GO_REF:0000002, GO:0042803=PMID:15809331, GO:0005829=GO_REF:0000024} Q9Y2S2 Lambda-crystallin homolog protein 20090720 {GO:0050104=IDA, GO:0006631=IEA, GO:0070403=IDA, GO:0003857=IEA, GO:0042803=IPI, GO:0005829=ISS} fatty acid metabolic process cytosol 3-hydroxyacyl-CoA dehydrogenase activity, L-gulonate 3-dehydrogenase activity, NAD+ binding, protein homodimerization activity Human CRYM HPA UniProtKB {GO:0050661=PMID:17242435, GO:0005886=GO_REF:0000052, GO:0007605=PMID:12471561, GO:0003714=PMID:11897713, GO:0042562=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0070327=PMID:11897713, GO:0000122=PMID:11897713, GO:0070324=PMID:9328354, GO:0042803=PMID:12590647, GO:0005739=GO_REF:0000019, GO:0047127=GO_REF:0000003, GO:0042403=GO_REF:0000019, GO:0005737=GO_REF:0000052} Q14894 Thiomorpholine-carboxylate dehydrogenase protein 20101115 {GO:0050661=IDA, GO:0005886=IDA, GO:0007605=IMP, GO:0003714=IMP, GO:0042562=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0070327=IMP, GO:0000122=IMP, GO:0070324=IDA, GO:0042803=IDA, GO:0005739=IEA, GO:0047127=IEA, GO:0042403=IEA, GO:0005737=IDA} negative regulation of transcription from RNA polymerase II promoter, sensory perception of sound, thyroid hormone metabolic process, thyroid hormone transport cytoplasm, mitochondrion, nucleolus, nucleus, plasma membrane NADP binding, hormone binding, protein homodimerization activity, thiomorpholine-carboxylate dehydrogenase activity, thyroid hormone binding, transcription corepressor activity Human CRYZ HPA UniProtKB {GO:0005794=GO_REF:0000052, GO:0042178=PMID:17497241, GO:0070404=PMID:17497241, GO:0003960=PMID:17497241, GO:0070402=PMID:17497241, GO:0043231=GO_REF:0000052, GO:0005829=PMID:17497241, GO:0005737=GO_REF:0000052, GO:0051289=PMID:17497241, GO:0016491=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0003730=PMID:17497241, GO:0007601=PMID:7835889} Q08257 Quinone oxidoreductase protein 20100326 {GO:0005794=IDA, GO:0042178=IDA, GO:0070404=IDA, GO:0003960=IDA, GO:0070402=IDA, GO:0043231=IDA, GO:0005829=IDA, GO:0005737=IDA, GO:0051289=IPI, GO:0016491=IEA, GO:0008270=IEA, GO:0003730=IDA, GO:0007601=TAS} protein homotetramerization, visual perception, xenobiotic catabolic process Golgi apparatus, cytoplasm, cytosol, intracellular membrane-bounded organelle NADH binding, NADPH binding, NADPH:quinone reductase activity, mRNA 3'-UTR binding, oxidoreductase activity, zinc ion binding Human CRYZL1 UniProtKB UniProtKB {GO:0050661=PMID:10191096, GO:0016491=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0003960=PMID:10191096, GO:0042375=PMID:10191096, GO:0005829=PMID:16780588} O95825 Quinone oxidoreductase-like protein 1 protein 20090218 {GO:0050661=NAS, GO:0016491=IEA, GO:0008270=IEA, GO:0003960=NAS, GO:0042375=NAS, GO:0005829=IDA} quinone cofactor metabolic process cytosol NADP binding, NADPH:quinone reductase activity, oxidoreductase activity, zinc ion binding Human CS HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0044262=GO_REF:0000002, GO:0006099=Reactome:REACT_1785, GO:0005975=PMID:9543345, GO:0005759=Reactome:REACT_1282, GO:0046912=GO_REF:0000002, GO:0004108=Reactome:REACT_1282, GO:0044281=Reactome:REACT_111217} O75390 Citrate synthase, mitochondrial protein 20110516 {GO:0005739=IDA, GO:0044262=IEA, GO:0006099=TAS, GO:0005975=IDA, GO:0005759=TAS, GO:0046912=IEA, GO:0004108=TAS, GO:0044281=TAS} carbohydrate metabolic process, cellular carbohydrate metabolic process, small molecule metabolic process, tricarboxylic acid cycle mitochondrial matrix, mitochondrion citrate (Si)-synthase activity, transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer Human CSAD InterPro UniProtKB {GO:0034641=Reactome:REACT_13, GO:0000096=Reactome:REACT_115639, GO:0000098=Reactome:REACT_115654, GO:0030170=GO_REF:0000002, GO:0016831=GO_REF:0000002, GO:0004782=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0042412=GO_REF:0000041, GO:0019752=GO_REF:0000002} Q9Y602 Cysteine sulfinic acid decarboxylase, isoform CRA_c protein 20130413 {GO:0034641=TAS, GO:0000096=TAS, GO:0000098=TAS, GO:0030170=IEA, GO:0016831=IEA, GO:0004782=IEA, GO:0044281=TAS, GO:0042412=IEA, GO:0019752=IEA} carboxylic acid metabolic process, cellular nitrogen compound metabolic process, small molecule metabolic process, sulfur amino acid catabolic process, sulfur amino acid metabolic process, taurine biosynthetic process carboxy-lyase activity, pyridoxal phosphate binding, sulfinoalanine decarboxylase activity Human InterPro:IPR002129|InterPro:IPR015421 CSAG1 null null {} null null null null {} null null null CSDC2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000029, GO:0006355=GO_REF:0000002, GO:0006398=GO_REF:0000029, GO:0003723=PMID:12801884, GO:0005634=GO_REF:0000029, GO:0003677=GO_REF:0000002} Q9Y534 Cold shock domain-containing protein C2 protein 20040206 {GO:0005737=NAS, GO:0006355=IEA, GO:0006398=NAS, GO:0003723=NAS, GO:0005634=NAS, GO:0003677=IEA} histone mRNA 3'-end processing, regulation of transcription, DNA-dependent cytoplasm, nucleus DNA binding, RNA binding Human CSDE1 PINC UniProtKB {GO:0006355=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005743=GO_REF:0000019, GO:0070966=PMID:15314026, GO:0003677=GO_REF:0000002, GO:0008584=PMID:2204029, GO:0070937=PMID:15314026} O75534 Cold shock domain-containing protein E1 protein 20030904 {GO:0006355=IEA, GO:0003723=IEA, GO:0005743=IEA, GO:0070966=IMP, GO:0003677=IEA, GO:0008584=TAS, GO:0070937=IDA} male gonad development, nuclear-transcribed mRNA catabolic process, no-go decay, regulation of transcription, DNA-dependent CRD-mediated mRNA stability complex, mitochondrial inner membrane DNA binding, RNA binding Human CSE1L IntAct UniProtKB {GO:0005515=PMID:17719542, GO:0005737=GO_REF:0000039, GO:0008283=PMID:7479798, GO:0005643=GO_REF:0000002, GO:0008565=GO_REF:0000002, GO:0006915=PMID:7479798, GO:0005634=PMID:9323134, GO:0008262=PMID:9323134, GO:0006886=GO_REF:0000002} P55060 Exportin-2 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0008283=TAS, GO:0005643=IEA, GO:0008565=IEA, GO:0006915=TAS, GO:0005634=TAS, GO:0008262=TAS, GO:0006886=IEA} apoptotic process, cell proliferation, intracellular protein transport cytoplasm, nuclear pore, nucleus importin-alpha export receptor activity, protein binding, protein transporter activity Human UniProtKB:P04637 CSF1 BHF-UCL UniProtKB {GO:0048471=PMID:1739124, GO:0008284=PMID:10652277, GO:0005886=GO_REF:0000039, GO:0008283=PMID:1791839, GO:0005157=PMID:19017797, GO:0046579=GO_REF:0000019, GO:0005615=PMID:2460758, GO:0030154=PMID:1791839, GO:0042803=PMID:3264878, GO:0006954=GO_REF:0000037, GO:0030278=GO_REF:0000019, GO:0048873=GO_REF:0000019, GO:0045657=PMID:18566389, GO:0045860=PMID:18566389, GO:0042476=GO_REF:0000019, GO:0030225=PMID:2460758, GO:0040018=GO_REF:0000019, GO:0030097=PMID:1791839, GO:0030335=PMID:18566389, GO:0010744=PMID:17244792, GO:0010743=PMID:18566389, GO:0030316=PMID:18606301, GO:0045672=PMID:15304486, GO:0060763=GO_REF:0000019, GO:0045651=PMID:2460758, GO:0005125=PMID:2460758, GO:0010628=PMID:1739124, GO:0043235=PMID:19017797, GO:0032270=PMID:1739124, GO:0003006=PMID:19017797, GO:0032946=PMID:2460758, GO:0016020=PMID:2460758, GO:0001503=GO_REF:0000019, GO:0042117=PMID:18566389, GO:0045087=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0060611=GO_REF:0000019, GO:0008083=PMID:2460758, GO:0042488=GO_REF:0000019, GO:0001954=PMID:18566389, GO:0060444=GO_REF:0000019} P09603 Macrophage colony-stimulating factor 1 protein 20090115 {GO:0048471=IDA, GO:0008284=IDA, GO:0005886=IEA, GO:0008283=NAS, GO:0005157=ISS, GO:0046579=IEA, GO:0005615=IDA, GO:0030154=NAS, GO:0042803=IDA, GO:0006954=IEA, GO:0030278=IEA, GO:0048873=IEA, GO:0045657=ISS, GO:0045860=ISS, GO:0042476=IEA, GO:0030225=TAS, GO:0040018=IEA, GO:0030097=NAS, GO:0030335=ISS, GO:0010744=IDA, GO:0010743=NAS, GO:0030316=IDA, GO:0045672=IDA, GO:0060763=IEA, GO:0045651=IDA, GO:0005125=IDA, GO:0010628=IDA, GO:0043235=ISS, GO:0032270=IDA, GO:0003006=ISS, GO:0032946=IDA, GO:0016020=NAS, GO:0001503=IEA, GO:0042117=NAS, GO:0045087=IEA, GO:0016021=IEA, GO:0060611=IEA, GO:0008083=IDA, GO:0042488=IEA, GO:0001954=ISS, GO:0060444=IEA} branching involved in mammary gland duct morphogenesis, cell differentiation, cell proliferation, developmental process involved in reproduction, hemopoiesis, homeostasis of number of cells within a tissue, inflammatory response, innate immune response, macrophage differentiation, mammary duct terminal end bud growth, mammary gland fat development, monocyte activation, odontogenesis, ossification, osteoclast differentiation, positive regulation of Ras protein signal transduction, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of cell-matrix adhesion, positive regulation of cellular protein metabolic process, positive regulation of gene expression, positive regulation of macrophage derived foam cell differentiation, positive regulation of macrophage differentiation, positive regulation of monocyte differentiation, positive regulation of mononuclear cell proliferation, positive regulation of multicellular organism growth, positive regulation of odontogenesis of dentin-containing tooth, positive regulation of osteoclast differentiation, positive regulation of protein kinase activity, regulation of macrophage derived foam cell differentiation, regulation of ossification extracellular space, integral to membrane, membrane, perinuclear region of cytoplasm, plasma membrane, receptor complex cytokine activity, growth factor activity, macrophage colony-stimulating factor receptor binding, protein homodimerization activity Human UniProtKB:P07141 CSF1R GOC UniProtKB {GO:0008284=PMID:15117969, GO:0005886=PMID:2421165, GO:0071902=GO_REF:0000024, GO:0008283=PMID:7683918, GO:0061098=PMID:7681396, GO:0008360=PMID:15117969, GO:0019221=PMID:20504948, GO:0045124=GO_REF:0000024, GO:2000147=PMID:15117969, GO:0042803=PMID:19017797, GO:0031529=GO_REF:0000024, GO:2000249=GO_REF:0000024, GO:0006954=PMID:19132917, GO:0046777=PMID:20504948, GO:0030225=PMID:19132917, GO:0030224=PMID:19132917, GO:0070374=GO_REF:0000024, GO:0060603=PMID:15117969, GO:0090197=PMID:20829061, GO:0038145=PMID:8981357, GO:0030097=PMID:7683918, GO:0036006=PMID:20504948, GO:0030335=GO_REF:0000024, GO:0009986=GO_REF:0000024, GO:0042517=GO_REF:0000024, GO:0048015=GO_REF:0000024, GO:0046488=GO_REF:0000024, GO:0030316=GO_REF:0000024, GO:0007275=PMID:8981357, GO:0018108=PMID:20504948, GO:0005524=GO_REF:0000037, GO:0045217=PMID:15117969, GO:0043235=PMID:19017797, GO:0007165=PMID:8981357, GO:0019955=PMID:19017797, GO:0016020=GO_REF:0000002, GO:0005887=PMID:2421165, GO:0071345=GO_REF:0000024, GO:0045087=GO_REF:0000037, GO:0001934=PMID:20504948, GO:0005011=PMID:20504948, GO:0004714=GO_REF:0000002, GO:0007169=GO_REF:0000024} P07333 Macrophage colony-stimulating factor 1 receptor protein 20130413 {GO:0008284=IMP, GO:0005886=TAS, GO:0071902=ISS, GO:0008283=IMP, GO:0061098=IMP, GO:0008360=IMP, GO:0019221=IMP, GO:0045124=ISS, GO:2000147=IMP, GO:0042803=ISS, GO:0031529=ISS, GO:2000249=ISS, GO:0006954=TAS, GO:0046777=IDA, GO:0030225=TAS, GO:0030224=TAS, GO:0070374=ISS, GO:0060603=TAS, GO:0090197=IMP, GO:0038145=TAS, GO:0030097=IMP, GO:0036006=IMP, GO:0030335=ISS, GO:0009986=ISS, GO:0042517=ISS, GO:0048015=ISS, GO:0046488=ISS, GO:0030316=ISS, GO:0007275=TAS, GO:0018108=IDA, GO:0005524=IEA, GO:0045217=IMP, GO:0043235=ISS, GO:0007165=TAS, GO:0019955=ISS, GO:0016020=IEA, GO:0005887=TAS, GO:0071345=ISS, GO:0045087=IEA, GO:0001934=IMP, GO:0005011=IMP, GO:0004714=IEA, GO:0007169=ISS} cell proliferation, cell-cell junction maintenance, cellular response to cytokine stimulus, cellular response to macrophage colony-stimulating factor stimulus, cytokine-mediated signaling pathway, hemopoiesis, inflammatory response, innate immune response, macrophage colony-stimulating factor signaling pathway, macrophage differentiation, mammary gland duct morphogenesis, monocyte differentiation, multicellular organismal development, osteoclast differentiation, peptidyl-tyrosine phosphorylation, phosphatidylinositol metabolic process, phosphatidylinositol-mediated signaling, positive regulation of ERK1 and ERK2 cascade, positive regulation of cell migration, positive regulation of cell motility, positive regulation of cell proliferation, positive regulation of chemokine secretion, positive regulation of protein phosphorylation, positive regulation of protein serine/threonine kinase activity, positive regulation of protein tyrosine kinase activity, positive regulation of tyrosine phosphorylation of Stat3 protein, protein autophosphorylation, regulation of actin cytoskeleton reorganization, regulation of bone resorption, regulation of cell shape, ruffle organization, signal transduction, transmembrane receptor protein tyrosine kinase signaling pathway cell surface, integral to plasma membrane, membrane, plasma membrane, receptor complex ATP binding, cytokine binding, macrophage colony-stimulating factor receptor activity, protein homodimerization activity, transmembrane receptor protein tyrosine kinase activity Human CSF2 BHF-UCL UniProtKB {GO:0005515=PMID:18692472, GO:0071803=PMID:15220135, GO:0043066=PMID:10666185, GO:0008284=GO_REF:0000019, GO:0010744=PMID:19032770, GO:0045740=PMID:9722506, GO:0032747=PMID:20027291, GO:0042523=PMID:9722506, GO:0001892=GO_REF:0000019, GO:0005576=Reactome:REACT_24024, GO:0097028=PMID:21149635, GO:0005125=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0010628=PMID:10666185, GO:0042045=GO_REF:0000019, GO:0006955=GO_REF:0000002, GO:0071222=GO_REF:0000019, GO:0042116=GO_REF:0000019, GO:0045918=PMID:10666185, GO:0043011=GO_REF:0000019, GO:0008083=GO_REF:0000037, GO:0005129=GO_REF:0000002} P04141 Granulocyte-macrophage colony-stimulating factor protein 20110220 {GO:0005515=IPI, GO:0071803=IDA, GO:0043066=IDA, GO:0008284=IEA, GO:0010744=IDA, GO:0045740=IDA, GO:0032747=IDA, GO:0042523=IDA, GO:0001892=IEA, GO:0005576=TAS, GO:0097028=IDA, GO:0005125=IEA, GO:0005615=IEA, GO:0010628=IDA, GO:0042045=IEA, GO:0006955=IEA, GO:0071222=IEA, GO:0042116=IEA, GO:0045918=IDA, GO:0043011=IEA, GO:0008083=IEA, GO:0005129=IEA} cellular response to lipopolysaccharide, dendritic cell differentiation, embryonic placenta development, epithelial fluid transport, immune response, macrophage activation, myeloid dendritic cell differentiation, negative regulation of apoptotic process, negative regulation of cytolysis, positive regulation of DNA replication, positive regulation of cell proliferation, positive regulation of gene expression, positive regulation of interleukin-23 production, positive regulation of macrophage derived foam cell differentiation, positive regulation of podosome assembly, positive regulation of tyrosine phosphorylation of Stat5 protein extracellular region, extracellular space cytokine activity, granulocyte macrophage colony-stimulating factor receptor binding, growth factor activity, protein binding Human CSF2RA Reactome UniProtKB {GO:0004896=GO_REF:0000002, GO:0005886=Reactome:REACT_24024, GO:0016020=GO_REF:0000002, GO:0005887=PMID:2555171, GO:0004872=PMID:1358805, GO:0005576=GO_REF:0000039} P15509 Granulocyte-macrophage colony-stimulating factor receptor subunit alpha protein 20100714 {GO:0004896=IEA, GO:0005886=TAS, GO:0016020=IEA, GO:0005887=TAS, GO:0004872=TAS, GO:0005576=IEA} extracellular region, integral to plasma membrane, membrane, plasma membrane cytokine receptor activity, receptor activity Human CSF2RB GOC UniProtKB {GO:0005515=PMID:20802515, GO:0038156=PMID:9410898, GO:0004896=GO_REF:0000002, GO:0007585=PMID:9410898, GO:0005886=Reactome:REACT_24024, GO:0004912=PMID:9410898, GO:0038043=PMID:9410898, GO:0004914=PMID:9410898, GO:0036016=PMID:9410898, GO:0007165=PMID:1702217, GO:0030526=PMID:9410898, GO:0016020=GO_REF:0000002, GO:0005887=PMID:1702217, GO:0004872=PMID:9410898} P32927 Cytokine receptor common subunit beta protein 20130413 {GO:0005515=IPI, GO:0038156=TAS, GO:0004896=IEA, GO:0007585=TAS, GO:0005886=TAS, GO:0004912=TAS, GO:0038043=TAS, GO:0004914=TAS, GO:0036016=TAS, GO:0007165=NAS, GO:0030526=TAS, GO:0016020=IEA, GO:0005887=NAS, GO:0004872=TAS} cellular response to interleukin-3, interleukin-3-mediated signaling pathway, interleukin-5-mediated signaling pathway, respiratory gaseous exchange, signal transduction granulocyte macrophage colony-stimulating factor receptor complex, integral to plasma membrane, membrane, plasma membrane cytokine receptor activity, interleukin-3 receptor activity, interleukin-5 receptor activity, protein binding, receptor activity Human CSF3 InterPro UniProtKB {GO:0051897=PMID:23001182, GO:0008284=GO_REF:0000019, GO:0019221=PMID:15664994, GO:0005130=PMID:2420009, GO:0050731=PMID:23001182, GO:2000251=PMID:23001182, GO:1901215=GO_REF:0000019, GO:0014068=PMID:23001182, GO:0005576=GO_REF:0000002, GO:0007275=PMID:2420009, GO:0042993=PMID:23001182, GO:0005125=GO_REF:0000002, GO:0005615=GO_REF:0000019, GO:0032092=PMID:23001182, GO:0033138=PMID:23001182, GO:0006955=GO_REF:0000002, GO:0071222=GO_REF:0000019, GO:0030838=PMID:23001182, GO:0071345=PMID:23001182, GO:0045944=PMID:23001182, GO:0030851=PMID:15664994, GO:0019899=PMID:12393522, GO:0008083=GO_REF:0000019} Q8N4W3 Colony stimulating factor 3 (Granulocyte) protein 20130413 {GO:0051897=IDA, GO:0008284=IEA, GO:0019221=NAS, GO:0005130=TAS, GO:0050731=IDA, GO:2000251=IDA, GO:1901215=IEA, GO:0014068=IDA, GO:0005576=IEA, GO:0007275=TAS, GO:0042993=IDA, GO:0005125=IEA, GO:0005615=IEA, GO:0032092=IDA, GO:0033138=IDA, GO:0006955=IEA, GO:0071222=IEA, GO:0030838=IDA, GO:0071345=IDA, GO:0045944=IDA, GO:0030851=NAS, GO:0019899=IPI, GO:0008083=IEA} cellular response to cytokine stimulus, cellular response to lipopolysaccharide, cytokine-mediated signaling pathway, granulocyte differentiation, immune response, multicellular organismal development, negative regulation of neuron death, positive regulation of actin cytoskeleton reorganization, positive regulation of actin filament polymerization, positive regulation of cell proliferation, positive regulation of peptidyl-serine phosphorylation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of protein binding, positive regulation of protein kinase B signaling cascade, positive regulation of transcription factor import into nucleus, positive regulation of transcription from RNA polymerase II promoter extracellular region, extracellular space cytokine activity, enzyme binding, granulocyte colony-stimulating factor receptor binding, growth factor activity Human InterPro:IPR003573 CSF3R PINC UniProtKB {GO:0007165=PMID:1371413, GO:0004896=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0005887=PMID:7542747, GO:0030593=GO_REF:0000019, GO:0042475=GO_REF:0000019, GO:0006952=PMID:7542747, GO:0004872=PMID:7542747, GO:0005576=GO_REF:0000039, GO:0007155=GO_REF:0000037} Q99062 Granulocyte colony-stimulating factor receptor protein 20040811 {GO:0007165=NAS, GO:0004896=IEA, GO:0016020=IEA, GO:0005887=TAS, GO:0030593=IEA, GO:0042475=IEA, GO:0006952=TAS, GO:0004872=TAS, GO:0005576=IEA, GO:0007155=IEA} cell adhesion, defense response, neutrophil chemotaxis, odontogenesis of dentin-containing tooth, signal transduction extracellular region, integral to plasma membrane, membrane cytokine receptor activity, receptor activity Human CSGALNACT1 Reactome UniProtKB {GO:0008037=PMID:11514575, GO:0051216=GO_REF:0000019, GO:0008283=PMID:11514575, GO:0044281=Reactome:REACT_111217, GO:0009653=PMID:11514575, GO:0015014=PMID:11514575, GO:0046872=PMID:12163485, GO:0005622=PMID:12163485, GO:0030206=Reactome:REACT_120989, GO:0030198=PMID:11514575, GO:0032580=GO_REF:0000039, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121315, GO:0047238=PMID:12163485, GO:0047237=PMID:12163485, GO:0050653=PMID:12163485, GO:0008955=PMID:11514575, GO:0050650=PMID:11788602, GO:0050651=PMID:11788602, GO:0016758=GO_REF:0000002, GO:0005975=Reactome:REACT_474, GO:0019276=PMID:11514575, GO:0015020=PMID:11514575, GO:0008376=PMID:11514575, GO:0007399=PMID:11514575, GO:0030166=PMID:11788602, GO:0030173=PMID:11514575, GO:0001958=GO_REF:0000019, GO:0000139=Reactome:REACT_120769, GO:0046398=PMID:11514575, GO:0030210=PMID:11514575} Q8TDX6 Chondroitin sulfate N-acetylgalactosaminyltransferase 1 protein 20130301 {GO:0008037=NAS, GO:0051216=IEA, GO:0008283=NAS, GO:0044281=TAS, GO:0009653=NAS, GO:0015014=NAS, GO:0046872=NAS, GO:0005622=IC, GO:0030206=TAS, GO:0030198=NAS, GO:0032580=IEA, GO:0030204=TAS, GO:0030203=TAS, GO:0047238=IDA, GO:0047237=IDA, GO:0050653=IDA, GO:0008955=IDA, GO:0050650=ISS, GO:0050651=ISS, GO:0016758=IEA, GO:0005975=TAS, GO:0019276=IDA, GO:0015020=IDA, GO:0008376=IDA, GO:0007399=NAS, GO:0030166=ISS, GO:0030173=NAS, GO:0001958=IEA, GO:0000139=TAS, GO:0046398=IDA, GO:0030210=NAS} UDP-N-acetylgalactosamine metabolic process, UDP-glucuronate metabolic process, anatomical structure morphogenesis, carbohydrate metabolic process, cartilage development, cell proliferation, cell recognition, chondroitin sulfate biosynthetic process, chondroitin sulfate metabolic process, chondroitin sulfate proteoglycan biosynthetic process, chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process, dermatan sulfate proteoglycan biosynthetic process, endochondral ossification, extracellular matrix organization, glycosaminoglycan metabolic process, heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process, heparin biosynthetic process, nervous system development, proteoglycan biosynthetic process, small molecule metabolic process Golgi cisterna membrane, Golgi membrane, integral to Golgi membrane, intracellular acetylgalactosaminyltransferase activity, glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity, glucuronosyltransferase activity, glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity, metal ion binding, peptidoglycan glycosyltransferase activity, transferase activity, transferring hexosyl groups Human CSH1 Reactome UniProtKB {GO:0007165=PMID:593368, GO:0007565=PMID:1378436, GO:0005179=GO_REF:0000037, GO:0005576=Reactome:REACT_116060, GO:0060397=Reactome:REACT_111133, GO:0046872=GO_REF:0000037} P01243 Chorionic somatomammotropin hormone protein 20130301 {GO:0007165=NAS, GO:0007565=TAS, GO:0005179=IEA, GO:0005576=TAS, GO:0060397=TAS, GO:0046872=IEA} JAK-STAT cascade involved in growth hormone signaling pathway, female pregnancy, signal transduction extracellular region hormone activity, metal ion binding Human CSH2 UniProtKB UniProtKB {GO:0005179=GO_REF:0000038, GO:0005576=GO_REF:0000040} H0YN17 Chorionic somatomammotropin hormone protein 20130413 {GO:0005179=IEA, GO:0005576=IEA} extracellular region hormone activity Human UniProtKB-SubCell:SL-0243 CSHL1 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0005179=PMID:2744760, GO:0005576=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0046872=GO_REF:0000037} Q14406 Chorionic somatomammotropin hormone-like 1 protein 20061026 {GO:0008150=ND, GO:0005179=NAS, GO:0005576=IEA, GO:0005575=ND, GO:0046872=IEA} biological_process cellular_component, extracellular region hormone activity, metal ion binding Human CSK HPA UniProtKB {GO:0005515=PMID:18614016, GO:0050852=Reactome:REACT_12526, GO:0008285=GO_REF:0000019, GO:0005886=Reactome:REACT_12601, GO:0032715=GO_REF:0000019, GO:0048709=GO_REF:0000019, GO:0031295=Reactome:REACT_19344, GO:0045779=GO_REF:0000019, GO:0043231=GO_REF:0000052, GO:0005829=Reactome:REACT_23821, GO:0050765=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0046777=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0005911=GO_REF:0000019, GO:0043406=GO_REF:0000019, GO:0071375=GO_REF:0000019, GO:0070373=GO_REF:0000019, GO:0010989=GO_REF:0000019, GO:0070064=GO_REF:0000019, GO:0033673=GO_REF:0000019, GO:0005813=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0019903=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0008022=PMID:8890164, GO:0005524=GO_REF:0000037, GO:0007596=Reactome:REACT_604, GO:0007420=GO_REF:0000019, GO:0045121=GO_REF:0000019, GO:0006468=PMID:1945408, GO:0004713=Reactome:REACT_12640, GO:0004715=GO_REF:0000003, GO:0060368=GO_REF:0000019, GO:0034332=GO_REF:0000019} P41240 Tyrosine-protein kinase CSK protein 20101115 {GO:0005515=IPI, GO:0050852=TAS, GO:0008285=IEA, GO:0005886=TAS, GO:0032715=IEA, GO:0048709=IEA, GO:0031295=TAS, GO:0045779=IEA, GO:0043231=IDA, GO:0005829=TAS, GO:0050765=IEA, GO:0005737=IDA, GO:0046777=IEA, GO:0007173=TAS, GO:0005911=IEA, GO:0043406=IEA, GO:0071375=IEA, GO:0070373=IEA, GO:0010989=IEA, GO:0070064=IEA, GO:0033673=IEA, GO:0005813=IDA, GO:0005794=IDA, GO:0019903=IEA, GO:0030168=TAS, GO:0008022=TAS, GO:0005524=IEA, GO:0007596=TAS, GO:0007420=IEA, GO:0045121=IEA, GO:0006468=TAS, GO:0004713=TAS, GO:0004715=IEA, GO:0060368=IEA, GO:0034332=IEA} T cell costimulation, T cell receptor signaling pathway, adherens junction organization, blood coagulation, brain development, cellular response to peptide hormone stimulus, epidermal growth factor receptor signaling pathway, negative regulation of ERK1 and ERK2 cascade, negative regulation of bone resorption, negative regulation of cell proliferation, negative regulation of interleukin-6 production, negative regulation of kinase activity, negative regulation of low-density lipoprotein particle clearance, negative regulation of phagocytosis, oligodendrocyte differentiation, platelet activation, positive regulation of MAP kinase activity, protein autophosphorylation, protein phosphorylation, regulation of Fc receptor mediated stimulatory signaling pathway Golgi apparatus, cell-cell junction, centrosome, cytoplasm, cytosol, intracellular membrane-bounded organelle, membrane raft, plasma membrane ATP binding, non-membrane spanning protein tyrosine kinase activity, proline-rich region binding, protein C-terminus binding, protein binding, protein phosphatase binding, protein tyrosine kinase activity Human CSMD1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q96PZ7 CUB and sushi domain-containing protein 1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 CSMD2 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q7Z408 CUB and sushi domain-containing protein 2 protein 20130413 {GO:0005886=IEA, GO:0016021=IEA} integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 CSMD3 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q7Z407 CUB and sushi domain-containing protein 3 protein 20130413 {GO:0005886=IEA, GO:0016021=IEA} integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 CSN1S1 UniProtKB UniProtKB {GO:0005215=GO_REF:0000002, GO:0005576=GO_REF:0000039} P47710 Alpha-S1-casein protein 20130413 {GO:0005215=IEA, GO:0005576=IEA} extracellular region transporter activity Human UniProtKB-SubCell:SL-0243 CSN2 GOC UniProtKB {GO:0004857=PMID:2387396, GO:0005215=GO_REF:0000002, GO:0005509=PMID:2387396, GO:0005576=Reactome:REACT_116088, GO:0006816=PMID:2387396, GO:0043086=PMID:2387396} P05814 Beta-casein protein 20130413 {GO:0004857=TAS, GO:0005215=IEA, GO:0005509=TAS, GO:0005576=TAS, GO:0006816=TAS, GO:0043086=TAS} calcium ion transport, negative regulation of catalytic activity extracellular region calcium ion binding, enzyme inhibitor activity, transporter activity Human CSN3 UniProtKB UniProtKB {GO:0007595=GO_REF:0000019, GO:0005576=GO_REF:0000029} P07498 Kappa-casein protein 20021104 {GO:0007595=IEA, GO:0005576=NAS} lactation extracellular region Human CSNK1A1 UniProtKB UniProtKB {GO:0005515=PMID:20708156, GO:0005813=PMID:21399614, GO:0005524=GO_REF:0000038, GO:0005829=Reactome:REACT_10134, GO:0007165=PMID:10777483, GO:0007067=GO_REF:0000037, GO:0004672=PMID:10777483, GO:0016607=PMID:18305108, GO:0004674=GO_REF:0000038, GO:0000777=GO_REF:0000039, GO:0005847=PMID:18305108, GO:0006468=PMID:18305108, GO:0016055=GO_REF:0000037, GO:0007166=PMID:10777483, GO:0051301=GO_REF:0000037} Q71TU5 Casein kinase I isoform alpha protein 20130413 {GO:0005515=IPI, GO:0005813=IDA, GO:0005524=IEA, GO:0005829=TAS, GO:0007165=NAS, GO:0007067=IEA, GO:0004672=TAS, GO:0016607=IDA, GO:0004674=IEA, GO:0000777=IEA, GO:0005847=IDA, GO:0006468=IDA, GO:0016055=IEA, GO:0007166=TAS, GO:0051301=IEA} Wnt receptor signaling pathway, cell division, cell surface receptor signaling pathway, mitosis, protein phosphorylation, signal transduction centrosome, condensed chromosome kinetochore, cytosol, mRNA cleavage and polyadenylation specificity factor complex, nuclear speck ATP binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB-KW:KW-0067 CSNK1A1L UniProtKB UniProtKB {GO:0000902=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0004674=GO_REF:0000037, GO:0030529=GO_REF:0000019, GO:0016055=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q8N752 Casein kinase I isoform alpha-like protein 20130413 {GO:0000902=IEA, GO:0005737=IEA, GO:0004674=IEA, GO:0030529=IEA, GO:0016055=IEA, GO:0005524=IEA} Wnt receptor signaling pathway, cell morphogenesis cytoplasm, ribonucleoprotein complex ATP binding, protein serine/threonine kinase activity Human UniProtKB-SubCell:SL-0086 CSNK1D BHF-UCL UniProtKB {GO:0005515=PMID:16618118, GO:0048471=PMID:16027726, GO:0005886=PMID:16027726, GO:0090263=PMID:20412773, GO:0032436=GO_REF:0000024, GO:0050321=GO_REF:0000003, GO:0005634=GO_REF:0000024, GO:0005829=Reactome:REACT_15470, GO:0000086=Reactome:REACT_2203, GO:0005876=PMID:10826492, GO:0016055=GO_REF:0000037, GO:0005813=PMID:21399614, GO:0005794=PMID:10826492, GO:0005819=PMID:10826492, GO:0051225=PMID:10826492, GO:0005524=GO_REF:0000037, GO:0032922=GO_REF:0000024, GO:0007165=PMID:8786104, GO:0004672=PMID:16618118, GO:0006281=PMID:8786104, GO:0004674=GO_REF:0000037, GO:0001934=PMID:20412773, GO:0042752=GO_REF:0000024, GO:0006468=PMID:16618118, GO:0000278=Reactome:REACT_152} P48730 Casein kinase I isoform delta protein 20100721 {GO:0005515=IPI, GO:0048471=IDA, GO:0005886=IDA, GO:0090263=IMP, GO:0032436=ISS, GO:0050321=IEA, GO:0005634=ISS, GO:0005829=TAS, GO:0000086=TAS, GO:0005876=IDA, GO:0016055=IEA, GO:0005813=IDA, GO:0005794=IDA, GO:0005819=IDA, GO:0051225=IDA, GO:0005524=IEA, GO:0032922=ISS, GO:0007165=TAS, GO:0004672=IDA, GO:0006281=TAS, GO:0004674=IEA, GO:0001934=IMP, GO:0042752=ISS, GO:0006468=IDA, GO:0000278=TAS} DNA repair, G2/M transition of mitotic cell cycle, Wnt receptor signaling pathway, circadian regulation of gene expression, mitotic cell cycle, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of protein phosphorylation, protein phosphorylation, regulation of circadian rhythm, signal transduction, spindle assembly Golgi apparatus, centrosome, cytosol, nucleus, perinuclear region of cytoplasm, plasma membrane, spindle, spindle microtubule ATP binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, tau-protein kinase activity Human CSNK1E IntAct UniProtKB {GO:0005515=PMID:22939624, GO:0090263=GO_REF:0000019, GO:0030178=GO_REF:0000019, GO:0032436=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_15470, GO:0007165=PMID:7797465, GO:0005737=GO_REF:0000019, GO:0006281=PMID:7797465, GO:0004672=GO_REF:0000024, GO:0004674=PMID:7797465, GO:0000086=Reactome:REACT_2203, GO:0030529=GO_REF:0000019, GO:0006468=GO_REF:0000024, GO:0034613=GO_REF:0000019, GO:0000278=Reactome:REACT_152} P49674 Casein kinase I isoform epsilon protein 20130415 {GO:0005515=IPI, GO:0090263=IEA, GO:0030178=IEA, GO:0032436=ISS, GO:0005634=ISS, GO:0005524=IEA, GO:0005829=TAS, GO:0007165=TAS, GO:0005737=IEA, GO:0006281=TAS, GO:0004672=ISS, GO:0004674=TAS, GO:0000086=TAS, GO:0030529=IEA, GO:0006468=ISS, GO:0034613=IEA, GO:0000278=TAS} DNA repair, G2/M transition of mitotic cell cycle, cellular protein localization, mitotic cell cycle, negative regulation of Wnt receptor signaling pathway, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, protein phosphorylation, signal transduction cytoplasm, cytosol, nucleus, ribonucleoprotein complex ATP binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB:P08238 CSNK1G1 HPA UniProtKB {GO:0051219=GO_REF:0000019, GO:0042277=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0046777=GO_REF:0000019, GO:0001948=GO_REF:0000019, GO:0000287=GO_REF:0000019, GO:0004674=GO_REF:0000019, GO:0016055=GO_REF:0000037, GO:0005524=GO_REF:0000019} Q9HCP0 Casein kinase I isoform gamma-1 protein 20090616 {GO:0051219=IEA, GO:0042277=IEA, GO:0005737=IDA, GO:0046777=IEA, GO:0001948=IEA, GO:0000287=IEA, GO:0004674=IEA, GO:0016055=IEA, GO:0005524=IEA} Wnt receptor signaling pathway, protein autophosphorylation cytoplasm ATP binding, glycoprotein binding, magnesium ion binding, peptide binding, phosphoprotein binding, protein serine/threonine kinase activity Human CSNK1G2 HPA UniProtKB {GO:0051219=GO_REF:0000019, GO:0006665=Reactome:REACT_19323, GO:0042277=GO_REF:0000019, GO:0000287=GO_REF:0000019, GO:0030148=Reactome:REACT_115810, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000019, GO:0005829=Reactome:REACT_19156, GO:0007165=PMID:9403068, GO:0005737=GO_REF:0000052, GO:0004672=GO_REF:0000002, GO:0001948=GO_REF:0000019, GO:0046777=GO_REF:0000019, GO:0004674=PMID:9403068, GO:0006468=PMID:9403068, GO:0016055=GO_REF:0000037} P78368 Casein kinase I isoform gamma-2 protein 20110516 {GO:0051219=IEA, GO:0006665=TAS, GO:0042277=IEA, GO:0000287=IEA, GO:0030148=TAS, GO:0044281=TAS, GO:0005524=IEA, GO:0005829=TAS, GO:0007165=TAS, GO:0005737=IDA, GO:0004672=IEA, GO:0001948=IEA, GO:0046777=IEA, GO:0004674=TAS, GO:0006468=TAS, GO:0016055=IEA} Wnt receptor signaling pathway, protein autophosphorylation, protein phosphorylation, signal transduction, small molecule metabolic process, sphingolipid biosynthetic process, sphingolipid metabolic process cytoplasm, cytosol ATP binding, glycoprotein binding, magnesium ion binding, peptide binding, phosphoprotein binding, protein kinase activity, protein serine/threonine kinase activity Human CSNK1G3 PINC UniProtKB {GO:0007165=PMID:9925945, GO:0005737=GO_REF:0000039, GO:0004672=PMID:9925945, GO:0004674=GO_REF:0000037, GO:0016055=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0006464=PMID:9925945} Q9Y6M4 Casein kinase I isoform gamma-3 protein 20030904 {GO:0007165=TAS, GO:0005737=IEA, GO:0004672=TAS, GO:0004674=IEA, GO:0016055=IEA, GO:0005524=IEA, GO:0006464=TAS} Wnt receptor signaling pathway, cellular protein modification process, signal transduction cytoplasm ATP binding, protein kinase activity, protein serine/threonine kinase activity Human CSNK2A1 BHF-UCL UniProtKB {GO:0005515=PMID:23455922, GO:0000236=Reactome:REACT_682, GO:0045732=PMID:20625391, GO:0008284=PMID:20625391, GO:0008013=GO_REF:0000019, GO:0005886=PMID:10799509, GO:0030307=PMID:20625391, GO:0051879=PMID:19387550, GO:0030177=PMID:12700239, GO:0005634=PMID:21282530, GO:0005829=Reactome:REACT_150239, GO:0046777=GO_REF:0000019, GO:0019888=GO_REF:0000019, GO:0016581=PMID:17827154, GO:0016580=PMID:17827154, GO:0007411=Reactome:REACT_18266, GO:0000087=Reactome:REACT_910, GO:0071174=PMID:11704824, GO:0016055=GO_REF:0000037, GO:0043154=PMID:16193064, GO:0031519=PMID:21282530, GO:0006355=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0007165=PMID:2174700, GO:0047485=PMID:11972058, GO:0061077=PMID:19387550, GO:0004674=PMID:20864032, GO:0006468=PMID:20625391, GO:0000278=Reactome:REACT_152} P68400 Casein kinase II subunit alpha protein 20090625 {GO:0005515=IPI, GO:0000236=TAS, GO:0045732=IDA, GO:0008284=IDA, GO:0008013=IEA, GO:0005886=TAS, GO:0030307=IDA, GO:0051879=TAS, GO:0030177=IMP, GO:0005634=IDA, GO:0005829=TAS, GO:0046777=IEA, GO:0019888=IEA, GO:0016581=IDA, GO:0016580=IDA, GO:0007411=TAS, GO:0000087=TAS, GO:0071174=IMP, GO:0016055=IEA, GO:0043154=IMP, GO:0031519=IDA, GO:0006355=IEA, GO:0005524=IEA, GO:0006351=IEA, GO:0007165=TAS, GO:0047485=IPI, GO:0061077=TAS, GO:0004674=IDA, GO:0006468=IDA, GO:0000278=TAS} M phase of mitotic cell cycle, Wnt receptor signaling pathway, axon guidance, chaperone-mediated protein folding, mitotic cell cycle, mitotic prometaphase, mitotic spindle checkpoint, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of Wnt receptor signaling pathway, positive regulation of cell growth, positive regulation of cell proliferation, positive regulation of protein catabolic process, protein autophosphorylation, protein phosphorylation, regulation of transcription, DNA-dependent, signal transduction, transcription, DNA-dependent NuRD complex, PcG protein complex, Sin3 complex, cytosol, nucleus, plasma membrane ATP binding, Hsp90 protein binding, beta-catenin binding, protein N-terminus binding, protein binding, protein phosphatase regulator activity, protein serine/threonine kinase activity Human CSNK2A2 IntAct UniProtKB {GO:0005515=PMID:23455922, GO:0031519=PMID:21282530, GO:0000236=Reactome:REACT_682, GO:0006355=GO_REF:0000037, GO:0006915=GO_REF:0000037, GO:0005634=PMID:21282530, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0005829=Reactome:REACT_150239, GO:0004672=GO_REF:0000002, GO:0047485=PMID:11972058, GO:0007411=Reactome:REACT_18266, GO:0004674=GO_REF:0000019, GO:0000087=Reactome:REACT_910, GO:0051726=GO_REF:0000019, GO:0071174=PMID:11704824, GO:0000278=Reactome:REACT_152, GO:0016055=GO_REF:0000037} P19784 Casein kinase II subunit alpha' protein 20130415 {GO:0005515=IPI, GO:0031519=IDA, GO:0000236=TAS, GO:0006355=IEA, GO:0006915=IEA, GO:0005634=IDA, GO:0005524=IEA, GO:0006351=IEA, GO:0005829=TAS, GO:0004672=IEA, GO:0047485=IPI, GO:0007411=TAS, GO:0004674=IEA, GO:0000087=TAS, GO:0051726=IEA, GO:0071174=IMP, GO:0000278=TAS, GO:0016055=IEA} M phase of mitotic cell cycle, Wnt receptor signaling pathway, apoptotic process, axon guidance, mitotic cell cycle, mitotic prometaphase, mitotic spindle checkpoint, regulation of cell cycle, regulation of transcription, DNA-dependent, transcription, DNA-dependent PcG protein complex, cytosol, nucleus ATP binding, protein N-terminus binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB:P68400 CSNK2B UniProtKB UniProtKB {GO:0045859=PMID:2666134, GO:0005515=PMID:23455922, GO:0000236=Reactome:REACT_682, GO:0008285=PMID:19324893, GO:0005886=PMID:19233263, GO:0033211=PMID:19233263, GO:0005634=PMID:21282530, GO:0046872=GO_REF:0000037, GO:0043623=PMID:19324893, GO:0005829=Reactome:REACT_150239, GO:0042802=PMID:21988832, GO:0019887=GO_REF:0000002, GO:0005737=PMID:19233263, GO:0016301=GO_REF:0000038, GO:0007411=Reactome:REACT_18266, GO:0000087=Reactome:REACT_910, GO:0016055=GO_REF:0000037, GO:0005956=GO_REF:0000002, GO:0031519=PMID:21282530, GO:0019904=PMID:11984006, GO:0010862=PMID:19592636, GO:0005102=PMID:19233263, GO:0007165=PMID:2513884, GO:0004674=PMID:1856204, GO:0061154=PMID:19592636, GO:0051101=PMID:19324893, GO:0000278=Reactome:REACT_152, GO:0043537=PMID:19592636, GO:0008134=PMID:19324893} Q5SRQ6 Casein kinase 2, beta polypeptide, isoform CRA_d protein 20130413 {GO:0045859=NAS, GO:0005515=IPI, GO:0000236=TAS, GO:0008285=TAS, GO:0005886=IDA, GO:0033211=IDA, GO:0005634=IDA, GO:0046872=IEA, GO:0043623=NAS, GO:0005829=TAS, GO:0042802=IPI, GO:0019887=IEA, GO:0005737=IDA, GO:0016301=IEA, GO:0007411=TAS, GO:0000087=TAS, GO:0016055=IEA, GO:0005956=IEA, GO:0031519=IDA, GO:0019904=IPI, GO:0010862=IDA, GO:0005102=IPI, GO:0007165=TAS, GO:0004674=TAS, GO:0061154=IMP, GO:0051101=NAS, GO:0000278=TAS, GO:0043537=IDA, GO:0008134=IPI} M phase of mitotic cell cycle, Wnt receptor signaling pathway, adiponectin-mediated signaling pathway, axon guidance, cellular protein complex assembly, endothelial tube morphogenesis, mitotic cell cycle, mitotic prometaphase, negative regulation of blood vessel endothelial cell migration, negative regulation of cell proliferation, positive regulation of pathway-restricted SMAD protein phosphorylation, regulation of DNA binding, regulation of protein kinase activity, signal transduction PcG protein complex, cytoplasm, cytosol, nucleus, plasma membrane, protein kinase CK2 complex identical protein binding, kinase activity, metal ion binding, protein binding, protein domain specific binding, protein kinase regulator activity, protein serine/threonine kinase activity, receptor binding, transcription factor binding Human UniProtKB-KW:KW-0418 CSPG4 Reactome UniProtKB {GO:0048771=GO_REF:0000037, GO:0008347=GO_REF:0000019, GO:0031258=GO_REF:0000039, GO:0009986=PMID:10587647, GO:0019901=PMID:10587647, GO:0005975=Reactome:REACT_474, GO:0005796=Reactome:REACT_121341, GO:0008283=GO_REF:0000019, GO:0050731=PMID:10587647, GO:0005576=Reactome:REACT_121341, GO:0044281=Reactome:REACT_111217, GO:0001525=GO_REF:0000037, GO:0030208=Reactome:REACT_120800, GO:0035556=PMID:10587647, GO:0030207=Reactome:REACT_120888, GO:0000187=GO_REF:0000019, GO:0030206=Reactome:REACT_120989, GO:0016324=GO_REF:0000039, GO:0005887=PMID:8790396, GO:0004871=GO_REF:0000037, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408, GO:0007169=GO_REF:0000019, GO:0043202=Reactome:REACT_121272} Q6UVK1 Chondroitin sulfate proteoglycan 4 protein 20130301 {GO:0048771=IEA, GO:0008347=IEA, GO:0031258=IEA, GO:0009986=TAS, GO:0019901=IPI, GO:0005975=TAS, GO:0005796=TAS, GO:0008283=IEA, GO:0050731=IDA, GO:0005576=TAS, GO:0044281=TAS, GO:0001525=IEA, GO:0030208=TAS, GO:0035556=IDA, GO:0030207=TAS, GO:0000187=IEA, GO:0030206=TAS, GO:0016324=IEA, GO:0005887=TAS, GO:0004871=IEA, GO:0030204=TAS, GO:0030203=TAS, GO:0007169=IEA, GO:0043202=TAS} activation of MAPK activity, angiogenesis, carbohydrate metabolic process, cell proliferation, chondroitin sulfate biosynthetic process, chondroitin sulfate catabolic process, chondroitin sulfate metabolic process, dermatan sulfate biosynthetic process, glial cell migration, glycosaminoglycan metabolic process, intracellular signal transduction, positive regulation of peptidyl-tyrosine phosphorylation, small molecule metabolic process, tissue remodeling, transmembrane receptor protein tyrosine kinase signaling pathway Golgi lumen, apical plasma membrane, cell surface, extracellular region, integral to plasma membrane, lamellipodium membrane, lysosomal lumen protein kinase binding, signal transducer activity Human CSPG5 IntAct UniProtKB {GO:0005515=PMID:12885772, GO:0031103=GO_REF:0000019, GO:0005794=PMID:12885772, GO:0005975=Reactome:REACT_474, GO:0005796=Reactome:REACT_121341, GO:0050804=GO_REF:0000019, GO:0005576=Reactome:REACT_121341, GO:0046907=PMID:12885772, GO:0044281=Reactome:REACT_111217, GO:0007399=PMID:12885772, GO:0030208=Reactome:REACT_120800, GO:0030207=Reactome:REACT_120888, GO:0030206=Reactome:REACT_120989, GO:0016020=PMID:9950058, GO:0005887=PMID:9950058, GO:0030660=PMID:12885772, GO:0005789=GO_REF:0000039, GO:0016021=PMID:12885772, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408, GO:0008083=PMID:12885772, GO:0040008=GO_REF:0000037, GO:0043202=Reactome:REACT_121272} O95196 Chondroitin sulfate proteoglycan 5 protein 20130415 {GO:0005515=IPI, GO:0031103=IEA, GO:0005794=IDA, GO:0005975=TAS, GO:0005796=TAS, GO:0050804=IEA, GO:0005576=TAS, GO:0046907=TAS, GO:0044281=TAS, GO:0007399=TAS, GO:0030208=TAS, GO:0030207=TAS, GO:0030206=TAS, GO:0016020=TAS, GO:0005887=TAS, GO:0030660=IDA, GO:0005789=IEA, GO:0016021=TAS, GO:0030204=TAS, GO:0030203=TAS, GO:0008083=TAS, GO:0040008=IEA, GO:0043202=TAS} axon regeneration, carbohydrate metabolic process, chondroitin sulfate biosynthetic process, chondroitin sulfate catabolic process, chondroitin sulfate metabolic process, dermatan sulfate biosynthetic process, glycosaminoglycan metabolic process, intracellular transport, nervous system development, regulation of growth, regulation of synaptic transmission, small molecule metabolic process Golgi apparatus, Golgi lumen, Golgi-associated vesicle membrane, endoplasmic reticulum membrane, extracellular region, integral to membrane, integral to plasma membrane, lysosomal lumen, membrane growth factor activity, protein binding Human UniProtKB:Q8BH60 CSPP1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0005813=PMID:21399614, GO:0000922=PMID:19129481, GO:0005874=GO_REF:0000037, GO:0005819=PMID:19129481, GO:0051781=PMID:19129481} Q1MSJ5 Centrosome and spindle pole-associated protein 1 protein 20110804 {GO:0005737=IEA, GO:0005813=IDA, GO:0000922=IDA, GO:0005874=IEA, GO:0005819=IDA, GO:0051781=IMP} positive regulation of cell division centrosome, cytoplasm, microtubule, spindle, spindle pole Human CSRNP1 HPA UniProtKB {GO:0003700=PMID:17726538, GO:0005730=GO_REF:0000052, GO:0048705=GO_REF:0000019, GO:0006915=PMID:11526492, GO:0005634=GO_REF:0000052, GO:0005575=GO_REF:0000015, GO:0009791=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0003674=GO_REF:0000015, GO:0060325=GO_REF:0000019, GO:0045944=PMID:17726538, GO:0060021=GO_REF:0000019, GO:0048008=GO_REF:0000019} Q96S65 Cysteine/serine-rich nuclear protein 1 protein 20111111 {GO:0003700=ISS, GO:0005730=IDA, GO:0048705=IEA, GO:0006915=NAS, GO:0005634=IDA, GO:0005575=ND, GO:0009791=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0003674=ND, GO:0060325=IEA, GO:0045944=ISS, GO:0060021=IEA, GO:0048008=IEA} apoptotic process, face morphogenesis, palate development, platelet-derived growth factor receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, post-embryonic development, skeletal system morphogenesis, transcription, DNA-dependent cellular_component, nucleolus, nucleus DNA binding, molecular_function, sequence-specific DNA binding transcription factor activity NOT Human CSRNP2 IntAct UniProtKB {GO:0005515=PMID:19389623, GO:0003700=PMID:17726538, GO:0019902=PMID:19389623, GO:0010923=PMID:19389623, GO:0045944=PMID:17726538, GO:0006915=GO_REF:0000037, GO:0005634=PMID:19389623, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9H175 Cysteine/serine-rich nuclear protein 2 protein 20130415 {GO:0005515=IPI, GO:0003700=ISS, GO:0019902=IDA, GO:0010923=IDA, GO:0045944=ISS, GO:0006915=IEA, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA} apoptotic process, negative regulation of phosphatase activity, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding, phosphatase binding, protein binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:P62136 CSRNP3 UniProtKB UniProtKB {GO:0043065=GO_REF:0000024, GO:0003700=PMID:17726538, GO:0010923=PMID:19389623, GO:0045944=PMID:17726538, GO:0006915=GO_REF:0000037, GO:0005634=PMID:17726538, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8WYN3 Cysteine/serine-rich nuclear protein 3 protein 20111103 {GO:0043065=ISS, GO:0003700=ISS, GO:0010923=IDA, GO:0045944=ISS, GO:0006915=IEA, GO:0005634=ISS, GO:0003677=IEA, GO:0006351=IEA} apoptotic process, negative regulation of phosphatase activity, positive regulation of apoptotic process, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity Human CSRP1 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002} P21291 Cysteine and glycine-rich protein 1 protein 20130413 {GO:0005634=IEA, GO:0008270=IEA} nucleus zinc ion binding Human UniProtKB-SubCell:SL-0191 CSRP2 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0005634=PMID:8626582, GO:0007275=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0030154=PMID:8626582} Q16527 Cysteine and glycine-rich protein 2 protein 20061026 {GO:0003674=ND, GO:0005634=NAS, GO:0007275=IEA, GO:0008270=IEA, GO:0030154=NAS} cell differentiation, multicellular organismal development nucleus molecular_function, zinc ion binding Human CSRP2BP BHF-UCL UniProtKB {GO:0005515=PMID:19060904, GO:0005737=GO_REF:0000039, GO:0043966=PMID:18838386, GO:0016573=GO_REF:0000019, GO:0030274=PMID:10924333, GO:0005671=PMID:18838386, GO:0005634=PMID:10924333, GO:0009790=GO_REF:0000019, GO:0022402=GO_REF:0000019, GO:0004402=PMID:19103755} Q9H8E8 Cysteine-rich protein 2-binding protein protein 20101105 {GO:0005515=IPI, GO:0005737=IEA, GO:0043966=IDA, GO:0016573=IEA, GO:0030274=NAS, GO:0005671=IDA, GO:0005634=IPI, GO:0009790=IEA, GO:0022402=IEA, GO:0004402=IDA} cell cycle process, embryo development, histone H3 acetylation, histone acetylation Ada2/Gcn5/Ada3 transcription activator complex, cytoplasm, nucleus LIM domain binding, histone acetyltransferase activity, protein binding Human CSRP3 BHF-UCL UniProtKB {GO:0005515=PMID:12127981, GO:0030018=PMID:12507422, GO:0031433=PMID:15582318, GO:0042805=PMID:12507422, GO:0005634=GO_REF:0000039, GO:0035995=PMID:12507422, GO:0060048=PMID:12507422, GO:0003300=PMID:12507422, GO:0007519=PMID:7954791, GO:0055003=PMID:12507422, GO:0008270=GO_REF:0000002, GO:0005856=GO_REF:0000039, GO:0008307=PMID:12507422} P50461 Cysteine and glycine-rich protein 3 protein 20120927 {GO:0005515=IPI, GO:0030018=IDA, GO:0031433=IPI, GO:0042805=ISS, GO:0005634=IEA, GO:0035995=IMP, GO:0060048=IMP, GO:0003300=IMP, GO:0007519=TAS, GO:0055003=ISS, GO:0008270=IEA, GO:0005856=IEA, GO:0008307=IMP} cardiac muscle contraction, cardiac muscle hypertrophy, cardiac myofibril assembly, detection of muscle stretch, skeletal muscle tissue development Z disc, cytoskeleton, nucleus actinin binding, protein binding, structural constituent of muscle, telethonin binding, zinc ion binding Human CST1 UniProtKB UniProtKB {GO:0004869=GO_REF:0000037, GO:0005576=GO_REF:0000039} P01037 Cystatin-SN protein 20130413 {GO:0004869=IEA, GO:0005576=IEA} extracellular region cysteine-type endopeptidase inhibitor activity Human UniProtKB-SubCell:SL-0243 CST11 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0004869=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0042742=GO_REF:0000037} Q9H112 Cystatin-11 protein 20130413 {GO:0005737=IEA, GO:0004869=IEA, GO:0005634=IEA, GO:0042742=IEA} defense response to bacterium cytoplasm, nucleus cysteine-type endopeptidase inhibitor activity Human UniProtKB-SubCell:SL-0086 CST2 UniProtKB UniProtKB {GO:0004869=GO_REF:0000037, GO:0005576=GO_REF:0000039} P09228 Cystatin-SA protein 20130413 {GO:0004869=IEA, GO:0005576=IEA} extracellular region cysteine-type endopeptidase inhibitor activity Human UniProtKB-SubCell:SL-0243 CST3 GOC UniProtKB {GO:0005515=PMID:15127951, GO:0048471=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0010711=PMID:10545518, GO:0004869=PMID:6203523, GO:0070301=GO_REF:0000019, GO:0004866=PMID:15127951, GO:0005783=GO_REF:0000019, GO:0010466=PMID:6203523, GO:0001654=GO_REF:0000019, GO:0002020=PMID:6203523, GO:0005615=PMID:18613859, GO:0048678=GO_REF:0000019, GO:0005764=GO_REF:0000019, GO:0010716=PMID:10545518, GO:0042747=GO_REF:0000019, GO:0009743=GO_REF:0000019, GO:0001540=PMID:18026102, GO:0060009=GO_REF:0000019, GO:0043067=GO_REF:0000019, GO:0060313=PMID:10545518, GO:0043292=GO_REF:0000019, GO:0060548=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0031667=GO_REF:0000019, GO:0007431=GO_REF:0000019, GO:0060311=PMID:10545518, GO:0043206=PMID:18026102, GO:0032355=GO_REF:0000019, GO:0001775=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0031965=GO_REF:0000019, GO:0010703=PMID:7890620, GO:0007566=GO_REF:0000019, GO:0005771=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0045740=GO_REF:0000019, GO:0009636=GO_REF:0000019, GO:0006915=GO_REF:0000019, GO:0006952=PMID:6203523, GO:0005576=PMID:18026102, GO:0031982=GO_REF:0000019, GO:0005604=GO_REF:0000019, GO:0010951=PMID:15127951, GO:0033267=GO_REF:0000019, GO:0034103=PMID:10545518, GO:0007420=GO_REF:0000019} P01034 Cystatin-C protein 20130413 {GO:0005515=IPI, GO:0048471=IEA, GO:0008284=IEA, GO:0010711=IEP, GO:0004869=IDA, GO:0070301=IEA, GO:0004866=IDA, GO:0005783=IEA, GO:0010466=IDA, GO:0001654=IEA, GO:0002020=IPI, GO:0005615=IDA, GO:0048678=IEA, GO:0005764=IEA, GO:0010716=IEP, GO:0042747=IEA, GO:0009743=IEA, GO:0001540=IPI, GO:0060009=IEA, GO:0043067=IEA, GO:0060313=IEP, GO:0043292=IEA, GO:0060548=IEA, GO:0043025=IEA, GO:0031667=IEA, GO:0007431=IEA, GO:0060311=IMP, GO:0043206=IGI, GO:0032355=IEA, GO:0001775=IEA, GO:0001666=IEA, GO:0031965=IEA, GO:0010703=IC, GO:0007566=IEA, GO:0005771=IEA, GO:0042493=IEA, GO:0045740=IEA, GO:0009636=IEA, GO:0006915=IEA, GO:0006952=IDA, GO:0005576=IMP, GO:0031982=IEA, GO:0005604=IEA, GO:0010951=IDA, GO:0033267=IEA, GO:0034103=IEP, GO:0007420=IEA} Sertoli cell development, apoptotic process, brain development, cell activation, cellular response to hydrogen peroxide, circadian sleep/wake cycle, REM sleep, defense response, embryo implantation, extracellular fibril organization, eye development, negative regulation of blood vessel remodeling, negative regulation of cell death, negative regulation of collagen catabolic process, negative regulation of elastin catabolic process, negative regulation of endopeptidase activity, negative regulation of extracellular matrix disassembly, negative regulation of histolysis, negative regulation of peptidase activity, positive regulation of DNA replication, positive regulation of cell proliferation, regulation of programmed cell death, regulation of tissue remodeling, response to axon injury, response to carbohydrate stimulus, response to drug, response to estradiol stimulus, response to hypoxia, response to nutrient levels, response to toxic substance, salivary gland development axon part, basement membrane, contractile fiber, endoplasmic reticulum, extracellular region, extracellular space, lysosome, multivesicular body, neuronal cell body, nuclear membrane, perinuclear region of cytoplasm, vesicle beta-amyloid binding, cysteine-type endopeptidase inhibitor activity, endopeptidase inhibitor activity, protease binding, protein binding Human CST4 UniProtKB UniProtKB {GO:0004869=GO_REF:0000037, GO:0005576=GO_REF:0000039} P01036 Cystatin-S protein 20130413 {GO:0004869=IEA, GO:0005576=IEA} extracellular region cysteine-type endopeptidase inhibitor activity Human UniProtKB-SubCell:SL-0243 CST5 UniProtKB UniProtKB {GO:0005515=PMID:8083219, GO:0004869=PMID:8083219, GO:0005576=PMID:8083219} P28325 Cystatin-D protein 20081014 {GO:0005515=IPI, GO:0004869=IDA, GO:0005576=IDA} extracellular region cysteine-type endopeptidase inhibitor activity, protein binding Human UniProtKB:P07858 CST6 PINC UniProtKB {GO:0004869=GO_REF:0000037, GO:0008544=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0009653=PMID:9099741, GO:0001533=GO_REF:0000019} Q15828 Cystatin-M protein 20031119 {GO:0004869=IEA, GO:0008544=IEA, GO:0005576=IEA, GO:0009653=TAS, GO:0001533=IEA} anatomical structure morphogenesis, epidermis development cornified envelope, extracellular region cysteine-type endopeptidase inhibitor activity Human CST7 GOC UniProtKB {GO:0010951=PMID:9632704, GO:0006955=PMID:9632704, GO:0005737=GO_REF:0000039, GO:0004869=GO_REF:0000037, GO:0004866=PMID:9632704, GO:0005576=GO_REF:0000039} O76096 Cystatin-F protein 20130413 {GO:0010951=TAS, GO:0006955=TAS, GO:0005737=IEA, GO:0004869=IEA, GO:0004866=TAS, GO:0005576=IEA} immune response, negative regulation of endopeptidase activity cytoplasm, extracellular region cysteine-type endopeptidase inhibitor activity, endopeptidase inhibitor activity Human CST9L UniProtKB UniProtKB {GO:0004869=GO_REF:0000037, GO:0005576=GO_REF:0000039} Q9H4G1 Cystatin-9-like protein 20130413 {GO:0004869=IEA, GO:0005576=IEA} extracellular region cysteine-type endopeptidase inhibitor activity Human UniProtKB-SubCell:SL-0243 CSTA HPA UniProtKB {GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0016337=PMID:21944047, GO:0018149=PMID:10908733, GO:0004869=PMID:6203523, GO:0030216=PMID:10908733, GO:0005198=PMID:10908733, GO:0010466=PMID:6203523, GO:0005634=GO_REF:0000052, GO:0002020=PMID:6203523, GO:0030674=PMID:10908733, GO:0001533=PMID:10908733} P01040 Cystatin-A protein 20101115 {GO:0005622=IEA, GO:0005737=IDA, GO:0016337=IMP, GO:0018149=IDA, GO:0004869=IDA, GO:0030216=IDA, GO:0005198=IDA, GO:0010466=IDA, GO:0005634=IDA, GO:0002020=IPI, GO:0030674=IDA, GO:0001533=IDA} cell-cell adhesion, keratinocyte differentiation, negative regulation of peptidase activity, peptide cross-linking cornified envelope, cytoplasm, intracellular, nucleus cysteine-type endopeptidase inhibitor activity, protease binding, protein binding, bridging, structural molecule activity Human CSTB GOC UniProtKB {GO:0010951=PMID:3053245, GO:0008344=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0004869=PMID:6203523, GO:0004866=PMID:3053245, GO:0010466=PMID:6203523, GO:0005730=GO_REF:0000052, GO:0042981=GO_REF:0000019, GO:0002020=PMID:6203523} P04080 Cystatin-B protein 20130413 {GO:0010951=TAS, GO:0008344=IEA, GO:0005737=IDA, GO:0004869=IDA, GO:0004866=TAS, GO:0010466=IDA, GO:0005730=IDA, GO:0042981=IEA, GO:0002020=IPI} adult locomotory behavior, negative regulation of endopeptidase activity, negative regulation of peptidase activity, regulation of apoptotic process cytoplasm, nucleolus cysteine-type endopeptidase inhibitor activity, endopeptidase inhibitor activity, protease binding Human CSTF1 IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0006379=PMID:1358884, GO:0008380=Reactome:REACT_1735, GO:0006378=PMID:1358884, GO:0006396=PMID:1741396, GO:0006369=Reactome:REACT_894, GO:0010467=Reactome:REACT_71, GO:0006366=Reactome:REACT_1366, GO:0003723=PMID:1741396, GO:0031124=Reactome:REACT_1849, GO:0005634=PMID:1358884, GO:0000398=Reactome:REACT_467, GO:0005654=Reactome:REACT_1935} Q05048 Cleavage stimulation factor subunit 1 protein 20130415 {GO:0005515=IPI, GO:0006379=TAS, GO:0008380=TAS, GO:0006378=TAS, GO:0006396=TAS, GO:0006369=TAS, GO:0010467=TAS, GO:0006366=TAS, GO:0003723=TAS, GO:0031124=TAS, GO:0005634=TAS, GO:0000398=TAS, GO:0005654=TAS} RNA processing, RNA splicing, gene expression, mRNA 3'-end processing, mRNA cleavage, mRNA polyadenylation, mRNA splicing, via spliceosome, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter nucleoplasm, nucleus RNA binding, protein binding Human UniProtKB:Q9H0E2 CSTF2 HPA UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:18688255, GO:0006379=PMID:1741396, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0006378=PMID:1741396, GO:0006366=Reactome:REACT_1366, GO:0003723=GO_REF:0000037, GO:0031124=Reactome:REACT_1849, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0071920=PMID:11598190, GO:0000166=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0005847=PMID:18305108, GO:0005654=Reactome:REACT_1935} P33240 Cleavage stimulation factor subunit 2 protein 20080205 {GO:0008380=TAS, GO:0005515=IPI, GO:0006379=TAS, GO:0010467=TAS, GO:0006369=TAS, GO:0006378=TAS, GO:0006366=TAS, GO:0003723=IEA, GO:0031124=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0071920=IDA, GO:0000166=IEA, GO:0000398=TAS, GO:0005847=IDA, GO:0005654=TAS} RNA splicing, gene expression, mRNA 3'-end processing, mRNA cleavage, mRNA polyadenylation, mRNA splicing, via spliceosome, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter cleavage body, mRNA cleavage and polyadenylation specificity factor complex, nucleolus, nucleoplasm, nucleus RNA binding, nucleic acid binding, nucleotide binding, protein binding NOT Human CSTF2T LIFEdb UniProtKB {GO:0005622=GO_REF:0000054, GO:0006397=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000019, GO:0005634=GO_REF:0000039} Q9H0L4 Cleavage stimulation factor subunit 2 tau variant protein 20100607 {GO:0005622=IDA, GO:0006397=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0005634=IEA} mRNA processing intracellular, nucleus RNA binding, nucleotide binding Human CSTF3 HPA UniProtKB {GO:0006379=PMID:7984242, GO:0008380=Reactome:REACT_1735, GO:0006396=GO_REF:0000002, GO:0006378=PMID:7984242, GO:0006369=Reactome:REACT_894, GO:0010467=Reactome:REACT_71, GO:0006366=Reactome:REACT_1366, GO:0003723=PMID:1741396, GO:0005730=GO_REF:0000052, GO:0031124=Reactome:REACT_1849, GO:0005634=GO_REF:0000052, GO:0005622=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0005654=Reactome:REACT_1935} Q12996 Cleavage stimulation factor subunit 3 protein 20111111 {GO:0006379=TAS, GO:0008380=TAS, GO:0006396=IEA, GO:0006378=TAS, GO:0006369=TAS, GO:0010467=TAS, GO:0006366=TAS, GO:0003723=TAS, GO:0005730=IDA, GO:0031124=TAS, GO:0005634=IDA, GO:0005622=IEA, GO:0000398=TAS, GO:0005654=TAS} RNA processing, RNA splicing, gene expression, mRNA 3'-end processing, mRNA cleavage, mRNA polyadenylation, mRNA splicing, via spliceosome, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter intracellular, nucleolus, nucleoplasm, nucleus RNA binding NOT Human CTAG1A LIFEdb UniProtKB {GO:0005737=GO_REF:0000054} P78358 Cancer/testis antigen 1 protein 20100607 {GO:0005737=IDA} cytoplasm Human CTAG1B null null {} null null null null {} null null null CTAG2 LIFEdb UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005813=GO_REF:0000054} O75638 Cancer/testis antigen 2 protein 20100607 {GO:0003674=ND, GO:0008150=ND, GO:0005813=IDA} biological_process centrosome molecular_function Human CTAGE1 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} Q9HC47 Cutaneous T-cell lymphoma-associated antigen 1 protein 20061026 {GO:0008150=ND, GO:0005575=ND, GO:0016021=IEA} biological_process cellular_component, integral to membrane Human CTAGE5 GOC UniProtKB {GO:0043085=PMID:9356211, GO:0008047=PMID:9356211} O15320 Cutaneous T-cell lymphoma-associated antigen 5 protein 20130413 {GO:0043085=TAS, GO:0008047=TAS} positive regulation of catalytic activity enzyme activator activity Human CTBP1 BHF-UCL UniProtKB {GO:0005515=PMID:16287852, GO:0034401=PMID:21102443, GO:0003700=GO_REF:0000019, GO:0008285=PMID:7479821, GO:0090241=PMID:21102443, GO:0005634=GO_REF:0000052, GO:0035067=PMID:21102443, GO:0019079=PMID:7479821, GO:0042803=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0051287=GO_REF:0000024, GO:0017053=PMID:19162039, GO:0070491=PMID:19162039, GO:0051726=PMID:21102443, GO:0007030=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0048037=GO_REF:0000002, GO:0001106=PMID:19162039, GO:0019904=PMID:19162039, GO:0005730=GO_REF:0000052, GO:0000122=PMID:19162039, GO:0008022=PMID:8440238, GO:0016616=GO_REF:0000002, GO:0050872=GO_REF:0000024, GO:0031065=PMID:21102443, GO:0019048=GO_REF:0000037, GO:0006468=PMID:8440238, GO:0045892=GO_REF:0000024, GO:0008134=PMID:16609867} Q13363 C-terminal-binding protein 1 protein 20121026 {GO:0005515=IPI, GO:0034401=IMP, GO:0003700=IEA, GO:0008285=TAS, GO:0090241=IMP, GO:0005634=IDA, GO:0035067=IMP, GO:0019079=TAS, GO:0042803=IEA, GO:0005829=IEA, GO:0051287=ISS, GO:0017053=IDA, GO:0070491=IPI, GO:0051726=IMP, GO:0007030=IEA, GO:0005667=IEA, GO:0048037=IEA, GO:0001106=IDA, GO:0019904=IDA, GO:0005730=IDA, GO:0000122=IMP, GO:0008022=TAS, GO:0016616=IEA, GO:0050872=ISS, GO:0031065=IMP, GO:0019048=IEA, GO:0006468=TAS, GO:0045892=ISS, GO:0008134=IPI} Golgi organization, negative regulation of cell proliferation, negative regulation of histone H4 acetylation, negative regulation of histone acetylation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of histone deacetylation, protein phosphorylation, regulation of cell cycle, regulation of transcription by chromatin organization, viral genome replication, virus-host interaction, white fat cell differentiation cytosol, nucleolus, nucleus, transcription factor complex, transcriptional repressor complex NAD binding, RNA polymerase II transcription corepressor activity, cofactor binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, protein C-terminus binding, protein binding, protein domain specific binding, protein homodimerization activity, repressing transcription factor binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human CTBP2 InterPro UniProtKB {GO:0005515=PMID:21988832, GO:0030054=GO_REF:0000037, GO:0008285=PMID:9479502, GO:0003714=GO_REF:0000019, GO:0045202=GO_REF:0000039, GO:0005634=GO_REF:0000024, GO:0019079=PMID:9479502, GO:0006351=GO_REF:0000037, GO:0016616=GO_REF:0000002, GO:0051287=GO_REF:0000002, GO:0050872=GO_REF:0000024, GO:0017053=GO_REF:0000024, GO:0045892=GO_REF:0000024} Q5SQP8 C-terminal-binding protein 2 protein 20130413 {GO:0005515=IPI, GO:0030054=IEA, GO:0008285=TAS, GO:0003714=IEA, GO:0045202=IEA, GO:0005634=ISS, GO:0019079=TAS, GO:0006351=IEA, GO:0016616=IEA, GO:0051287=IEA, GO:0050872=ISS, GO:0017053=ISS, GO:0045892=ISS} negative regulation of cell proliferation, negative regulation of transcription, DNA-dependent, transcription, DNA-dependent, viral genome replication, white fat cell differentiation cell junction, nucleus, synapse, transcriptional repressor complex NAD binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, protein binding, transcription corepressor activity Human InterPro:IPR006139 CTBS UniProtKB UniProtKB {GO:0009313=GO_REF:0000019, GO:0006032=GO_REF:0000019, GO:0005764=GO_REF:0000039, GO:0004568=GO_REF:0000019} Q01459 Di-N-acetylchitobiase protein 20130413 {GO:0009313=IEA, GO:0006032=IEA, GO:0005764=IEA, GO:0004568=IEA} chitin catabolic process, oligosaccharide catabolic process lysosome chitinase activity Human UniProtKB-SubCell:SL-0158 CTC1 UniProtKB UniProtKB {GO:0005515=PMID:19854130, GO:0070188=GO_REF:0000024, GO:0000723=PMID:19854131, GO:0003697=GO_REF:0000024, GO:0045740=GO_REF:0000024, GO:0005634=PMID:19854130, GO:0000784=PMID:19854130} Q2NKJ3 CST complex subunit CTC1 protein 20100222 {GO:0005515=IPI, GO:0070188=ISS, GO:0000723=IMP, GO:0003697=ISS, GO:0045740=ISS, GO:0005634=IDA, GO:0000784=IDA} positive regulation of DNA replication, telomere maintenance Stn1-Ten1 complex, nuclear chromosome, telomeric region, nucleus protein binding, single-stranded DNA binding Human UniProtKB:Q8K2X3 CTCF UniProtKB UniProtKB {GO:0005515=PMID:19505873, GO:0000793=PMID:16107875, GO:0003700=PMID:9591631, GO:0044212=PMID:18413740, GO:0005634=PMID:9407128, GO:0035065=GO_REF:0000019, GO:0010216=GO_REF:0000019, GO:0007059=GO_REF:0000037, GO:0016584=PMID:18654629, GO:0070602=PMID:18550811, GO:0003714=PMID:8649389, GO:0005730=PMID:16595548, GO:0006351=GO_REF:0000037, GO:0040030=PMID:16815976, GO:0043565=PMID:17827499, GO:0010628=PMID:18347100, GO:0031060=GO_REF:0000019, GO:0006349=GO_REF:0000019, GO:0040029=PMID:16815976, GO:0043035=PMID:17827499, GO:0008270=PMID:8649389, GO:0005654=PMID:16107875, GO:0045893=PMID:19322193, GO:0045892=PMID:18413740, GO:0000775=PMID:18550811, GO:0016568=GO_REF:0000037} P49711 Transcriptional repressor CTCF protein 20120708 {GO:0005515=IPI, GO:0000793=IDA, GO:0003700=IDA, GO:0044212=IDA, GO:0005634=IDA, GO:0035065=IEA, GO:0010216=IEA, GO:0007059=IEA, GO:0016584=IDA, GO:0070602=NAS, GO:0003714=TAS, GO:0005730=IDA, GO:0006351=IEA, GO:0040030=IMP, GO:0043565=IDA, GO:0010628=IMP, GO:0031060=IEA, GO:0006349=IEA, GO:0040029=IMP, GO:0043035=IDA, GO:0008270=TAS, GO:0005654=IDA, GO:0045893=IMP, GO:0045892=IDA, GO:0000775=IDA, GO:0016568=IEA} chromatin modification, chromosome segregation, maintenance of DNA methylation, negative regulation of transcription, DNA-dependent, nucleosome positioning, positive regulation of gene expression, positive regulation of transcription, DNA-dependent, regulation of centromeric sister chromatid cohesion, regulation of gene expression by genetic imprinting, regulation of gene expression, epigenetic, regulation of histone acetylation, regulation of histone methylation, regulation of molecular function, epigenetic, transcription, DNA-dependent chromosome, centromeric region, condensed chromosome, nucleolus, nucleoplasm, nucleus chromatin insulator sequence binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity, transcription regulatory region DNA binding, zinc ion binding Human UniProtKB:Q01664 CTCFL HPA UniProtKB {GO:0005515=PMID:18765639, GO:0044212=PMID:18413740, GO:0016571=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0003677=PMID:18413740, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000024, GO:0010628=PMID:18413740, GO:0042393=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0007049=GO_REF:0000037, GO:0006349=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0045893=PMID:18413740, GO:0051569=PMID:18765639, GO:0043046=GO_REF:0000024} Q8NI51 Transcriptional repressor CTCFL protein 20101115 {GO:0005515=IPI, GO:0044212=IDA, GO:0016571=ISS, GO:0005634=IDA, GO:0003676=IEA, GO:0003677=IDA, GO:0006351=IEA, GO:0043565=ISS, GO:0010628=IDA, GO:0042393=ISS, GO:0005737=IDA, GO:0007049=IEA, GO:0006349=ISS, GO:0008270=IEA, GO:0045893=IDA, GO:0051569=IMP, GO:0043046=ISS} DNA methylation involved in gamete generation, cell cycle, histone methylation, positive regulation of gene expression, positive regulation of transcription, DNA-dependent, regulation of gene expression by genetic imprinting, regulation of histone H3-K4 methylation, transcription, DNA-dependent cytoplasm, nucleus DNA binding, histone binding, nucleic acid binding, protein binding, sequence-specific DNA binding, transcription regulatory region DNA binding, zinc ion binding Human CTDNEP1 IntAct UniProtKB {GO:0005515=PMID:22134922, GO:0031965=PMID:22134922, GO:0034504=PMID:22134922, GO:0010867=PMID:22134922, GO:0071595=PMID:22134922, GO:0005635=PMID:17420445, GO:0016791=GO_REF:0000002, GO:0005737=PMID:22134922, GO:0006470=PMID:22134922, GO:0005789=PMID:17420445, GO:0006998=PMID:17420445, GO:0016021=GO_REF:0000037, GO:0004722=PMID:17420445} O95476 CTD nuclear envelope phosphatase 1 protein 20130415 {GO:0005515=IPI, GO:0031965=IDA, GO:0034504=IDA, GO:0010867=IGI, GO:0071595=IDA, GO:0005635=IDA, GO:0016791=IEA, GO:0005737=IDA, GO:0006470=IDA, GO:0005789=IDA, GO:0006998=IDA, GO:0016021=IEA, GO:0004722=IMP} nuclear envelope organization, positive regulation of triglyceride biosynthetic process, protein dephosphorylation, protein localization to nucleus Nem1-Spo7 phosphatase complex, cytoplasm, endoplasmic reticulum membrane, integral to membrane, nuclear envelope, nuclear membrane phosphatase activity, protein binding, protein serine/threonine phosphatase activity Human UniProtKB:Q8N9A8 CTDP1 HPA UniProtKB {GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0010458=PMID:22692537, GO:0006368=Reactome:REACT_1845, GO:0005813=PMID:22692537, GO:0006366=Reactome:REACT_1366, GO:0003899=PMID:9765293, GO:0005730=GO_REF:0000052, GO:0005819=PMID:22692537, GO:0030496=PMID:22692537, GO:0005634=GO_REF:0000052, GO:0015629=GO_REF:0000052, GO:0051233=PMID:22692537, GO:0050434=Reactome:REACT_6162, GO:0007067=GO_REF:0000037, GO:0000922=PMID:22692537, GO:0005737=GO_REF:0000037, GO:0006470=PMID:22692537, GO:0016032=Reactome:REACT_6256, GO:0005654=Reactome:REACT_6355, GO:0004721=GO_REF:0000002, GO:0051301=GO_REF:0000037, GO:0008420=PMID:12721286} Q9Y5B0 RNA polymerase II subunit A C-terminal domain phosphatase protein 20110516 {GO:0022415=TAS, GO:0010467=TAS, GO:0010458=IMP, GO:0006368=TAS, GO:0005813=IDA, GO:0006366=TAS, GO:0003899=TAS, GO:0005730=IDA, GO:0005819=IDA, GO:0030496=IDA, GO:0005634=IDA, GO:0015629=IDA, GO:0051233=IDA, GO:0050434=TAS, GO:0007067=IEA, GO:0000922=IDA, GO:0005737=IEA, GO:0006470=IDA, GO:0016032=TAS, GO:0005654=TAS, GO:0004721=IEA, GO:0051301=IEA, GO:0008420=IDA} cell division, exit from mitosis, gene expression, mitosis, positive regulation of viral transcription, protein dephosphorylation, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, viral reproduction, viral reproductive process actin cytoskeleton, centrosome, cytoplasm, midbody, nucleolus, nucleoplasm, nucleus, spindle, spindle midzone, spindle pole CTD phosphatase activity, DNA-directed RNA polymerase activity, phosphoprotein phosphatase activity Human CTDSP1 UniProtKB UniProtKB {GO:0005515=PMID:12721286, GO:0016791=GO_REF:0000002, GO:0006470=PMID:12721286, GO:0006357=PMID:12721286, GO:0045665=GO_REF:0000019, GO:0050768=GO_REF:0000019, GO:0005634=PMID:12721286, GO:0046872=GO_REF:0000037, GO:0008420=PMID:12721286} Q9GZU7 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 protein 20091123 {GO:0005515=IPI, GO:0016791=IEA, GO:0006470=IDA, GO:0006357=IDA, GO:0045665=IEA, GO:0050768=IEA, GO:0005634=IDA, GO:0046872=IEA, GO:0008420=IDA} negative regulation of neurogenesis, negative regulation of neuron differentiation, protein dephosphorylation, regulation of transcription from RNA polymerase II promoter nucleus CTD phosphatase activity, metal ion binding, phosphatase activity, protein binding Human CTDSP2 Reactome UniProtKB {GO:0016791=GO_REF:0000002, GO:0006470=PMID:12721286, GO:0005654=Reactome:REACT_115909, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0046872=GO_REF:0000037, GO:0030968=Reactome:REACT_18356, GO:0008420=PMID:12721286} O14595 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 protein 20130301 {GO:0016791=IEA, GO:0006470=IDA, GO:0005654=TAS, GO:0006987=TAS, GO:0044267=TAS, GO:0046872=IEA, GO:0030968=TAS, GO:0008420=IDA} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, protein dephosphorylation nucleoplasm CTD phosphatase activity, metal ion binding, phosphatase activity Human CTDSPL UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0016791=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0004721=GO_REF:0000003, GO:0005575=GO_REF:0000015, GO:0046872=GO_REF:0000037} O15194 CTD small phosphatase-like protein protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0016791=IEA, GO:0005634=IEA, GO:0004721=IEA, GO:0005575=ND, GO:0046872=IEA} biological_process cellular_component, nucleus metal ion binding, molecular_function, phosphatase activity, phosphoprotein phosphatase activity Human CTDSPL2 UniProtKB UniProtKB {GO:0004721=GO_REF:0000037} Q05D32 CTD small phosphatase-like protein 2 protein 20130413 {GO:0004721=IEA} phosphoprotein phosphatase activity Human UniProtKB-KW:KW-0904 CTF1 PINC UniProtKB {GO:0005146=GO_REF:0000019, GO:0008284=PMID:7862649, GO:0048861=GO_REF:0000019, GO:0007517=PMID:8833032, GO:0008283=PMID:7738033, GO:0048666=GO_REF:0000019, GO:0007267=PMID:7862649, GO:0005576=PMID:7862649, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037, GO:0007399=PMID:7738033} Q16619 Cardiotrophin-1 protein 20030904 {GO:0005146=IEA, GO:0008284=TAS, GO:0048861=IEA, GO:0007517=TAS, GO:0008283=TAS, GO:0048666=IEA, GO:0007267=TAS, GO:0005576=TAS, GO:0005615=IEA, GO:0005125=IEA, GO:0007399=TAS} cell proliferation, cell-cell signaling, leukemia inhibitory factor signaling pathway, muscle organ development, nervous system development, neuron development, positive regulation of cell proliferation extracellular region, extracellular space cytokine activity, leukemia inhibitory factor receptor binding Human CTGF HPA UniProtKB {GO:0060401=GO_REF:0000019, GO:0010467=Reactome:REACT_71, GO:0005801=GO_REF:0000019, GO:0006367=Reactome:REACT_118713, GO:0070278=GO_REF:0000019, GO:0001558=GO_REF:0000002, GO:0005615=GO_REF:0000019, GO:0035988=GO_REF:0000019, GO:0030154=GO_REF:0000019, GO:0043231=GO_REF:0000052, GO:0010942=GO_REF:0000019, GO:0005938=GO_REF:0000019, GO:0032355=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0005520=GO_REF:0000002, GO:0005794=GO_REF:0000052, GO:0034059=GO_REF:0000019, GO:0051385=GO_REF:0000019, GO:0032330=GO_REF:0000019, GO:0043280=GO_REF:0000019, GO:0005178=GO_REF:0000019, GO:0070542=GO_REF:0000019, GO:0032967=GO_REF:0000019, GO:0001503=GO_REF:0000019, GO:0008544=PMID:10809757, GO:0001502=GO_REF:0000019, GO:0007229=GO_REF:0000019, GO:0008543=GO_REF:0000019, GO:0008083=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0005886=PMID:10809757, GO:0030324=GO_REF:0000019, GO:0043434=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0005829=GO_REF:0000019, GO:0035556=GO_REF:0000019, GO:0010260=GO_REF:0000019, GO:0060452=GO_REF:0000019, GO:0001968=GO_REF:0000019, GO:0008201=GO_REF:0000019, GO:0043200=GO_REF:0000019, GO:0050867=GO_REF:0000019, GO:0072593=GO_REF:0000019, GO:0005578=GO_REF:0000039, GO:0009611=PMID:10809757, GO:0005576=Reactome:REACT_116163, GO:0070318=GO_REF:0000019, GO:0001525=GO_REF:0000019, GO:0009749=GO_REF:0000019, GO:0010628=GO_REF:0000019, GO:0006260=GO_REF:0000037, GO:0007160=GO_REF:0000019, GO:0016477=GO_REF:0000019, GO:0010629=GO_REF:0000019, GO:0001934=GO_REF:0000019} P29279 Connective tissue growth factor protein 20111111 {GO:0060401=IEA, GO:0010467=TAS, GO:0005801=IEA, GO:0006367=TAS, GO:0070278=IEA, GO:0001558=IEA, GO:0005615=IEA, GO:0035988=IEA, GO:0030154=IEA, GO:0043231=IDA, GO:0010942=IEA, GO:0005938=IEA, GO:0032355=IEA, GO:0044255=TAS, GO:0005520=IEA, GO:0005794=IDA, GO:0034059=IEA, GO:0051385=IEA, GO:0032330=IEA, GO:0043280=IEA, GO:0005178=IEA, GO:0070542=IEA, GO:0032967=IEA, GO:0001503=IEA, GO:0008544=TAS, GO:0001502=IEA, GO:0007229=IEA, GO:0008543=IEA, GO:0008083=IEA, GO:0008284=IEA, GO:0048471=IEA, GO:0005886=TAS, GO:0030324=IEA, GO:0043434=IEA, GO:0044281=TAS, GO:0005829=IEA, GO:0035556=IEA, GO:0010260=IEA, GO:0060452=IEA, GO:0001968=IEA, GO:0008201=IEA, GO:0043200=IEA, GO:0050867=IEA, GO:0072593=IEA, GO:0005578=IEA, GO:0009611=TAS, GO:0005576=TAS, GO:0070318=IEA, GO:0001525=IEA, GO:0009749=IEA, GO:0010628=IEA, GO:0006260=IEA, GO:0007160=IEA, GO:0016477=IEA, GO:0010629=IEA, GO:0001934=IEA} DNA replication, angiogenesis, cartilage condensation, cell differentiation, cell migration, cell-matrix adhesion, cellular lipid metabolic process, chondrocyte proliferation, cytosolic calcium ion transport, epidermis development, extracellular matrix constituent secretion, fibroblast growth factor receptor signaling pathway, gene expression, integrin-mediated signaling pathway, intracellular signal transduction, lung development, negative regulation of gene expression, organ senescence, ossification, positive regulation of G0 to G1 transition, positive regulation of cardiac muscle contraction, positive regulation of cell activation, positive regulation of cell death, positive regulation of cell proliferation, positive regulation of collagen biosynthetic process, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of gene expression, positive regulation of protein phosphorylation, reactive oxygen species metabolic process, regulation of cell growth, regulation of chondrocyte differentiation, response to amino acid stimulus, response to anoxia, response to estradiol stimulus, response to fatty acid, response to glucose stimulus, response to mineralocorticoid stimulus, response to peptide hormone stimulus, response to wounding, small molecule metabolic process, transcription initiation from RNA polymerase II promoter Golgi apparatus, cell cortex, cis-Golgi network, cytosol, extracellular region, extracellular space, intracellular membrane-bounded organelle, perinuclear region of cytoplasm, plasma membrane, proteinaceous extracellular matrix fibronectin binding, growth factor activity, heparin binding, insulin-like growth factor binding, integrin binding Human CTH HPA UniProtKB {GO:0005515=PMID:22169477, GO:0019344=PMID:10212249, GO:0005516=GO_REF:0000037, GO:0070814=PMID:19019829, GO:0019346=Reactome:REACT_115589, GO:0006534=PMID:1339280, GO:0005634=GO_REF:0000052, GO:0044540=PMID:22169477, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0030968=PMID:22169477, GO:0005829=Reactome:REACT_116121, GO:0018272=PMID:19019829, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000052, GO:0051092=GO_REF:0000019, GO:0051289=PMID:19019829, GO:0004123=Reactome:REACT_116098, GO:0043123=GO_REF:0000019, GO:0016846=Reactome:REACT_115918, GO:0043066=GO_REF:0000019, GO:0047982=Reactome:REACT_116033, GO:0080146=Reactome:REACT_116121, GO:0000096=Reactome:REACT_115639, GO:0000098=Reactome:REACT_115654, GO:0030170=PMID:10212249, GO:0044524=PMID:22169477} P32929 Cystathionine gamma-lyase protein 20100326 {GO:0005515=IPI, GO:0019344=IDA, GO:0005516=IEA, GO:0070814=IDA, GO:0019346=TAS, GO:0006534=TAS, GO:0005634=IDA, GO:0044540=IMP, GO:0044281=TAS, GO:0003824=IEA, GO:0030968=TAS, GO:0005829=TAS, GO:0018272=IDA, GO:0034641=TAS, GO:0005737=IDA, GO:0051092=IEA, GO:0051289=IPI, GO:0004123=TAS, GO:0043123=IEA, GO:0016846=TAS, GO:0043066=IEA, GO:0047982=TAS, GO:0080146=TAS, GO:0000096=TAS, GO:0000098=TAS, GO:0030170=IDA, GO:0044524=IMP} cellular nitrogen compound metabolic process, cysteine biosynthetic process, cysteine metabolic process, endoplasmic reticulum unfolded protein response, hydrogen sulfide biosynthetic process, negative regulation of apoptotic process, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB transcription factor activity, protein homotetramerization, protein sulfhydration, protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine, small molecule metabolic process, sulfur amino acid catabolic process, sulfur amino acid metabolic process, transsulfuration cytoplasm, cytosol, nucleus L-cysteine desulfhydrase activity, L-cystine L-cysteine-lyase (deaminating), calmodulin binding, carbon-sulfur lyase activity, catalytic activity, cystathionine gamma-lyase activity, homocysteine desulfhydrase activity, protein binding, pyridoxal phosphate binding Human CTHRC1 MGI UniProtKB {GO:0017147=GO_REF:0000019, GO:0005581=GO_REF:0000037, GO:0043932=GO_REF:0000019, GO:0060122=GO_REF:0000019, GO:0090177=GO_REF:0000019, GO:0005615=PMID:18467647, GO:0032092=GO_REF:0000019, GO:0005109=GO_REF:0000019, GO:0031012=GO_REF:0000019, GO:0045669=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0016477=GO_REF:0000019, GO:0090103=GO_REF:0000019, GO:0033690=GO_REF:0000019, GO:0090090=GO_REF:0000019, GO:0060071=GO_REF:0000019} Q96CG8 Collagen triple helix repeat-containing protein 1 protein 20111227 {GO:0017147=IEA, GO:0005581=IEA, GO:0043932=IEA, GO:0060122=IEA, GO:0090177=IEA, GO:0005615=IDA, GO:0032092=IEA, GO:0005109=IEA, GO:0031012=IEA, GO:0045669=IEA, GO:0005737=IEA, GO:0016477=IEA, GO:0090103=IEA, GO:0033690=IEA, GO:0090090=IEA, GO:0060071=IEA} Wnt receptor signaling pathway, planar cell polarity pathway, cell migration, cochlea morphogenesis, establishment of planar polarity involved in neural tube closure, inner ear receptor stereocilium organization, negative regulation of canonical Wnt receptor signaling pathway, ossification involved in bone remodeling, positive regulation of osteoblast differentiation, positive regulation of osteoblast proliferation, positive regulation of protein binding collagen, cytoplasm, extracellular matrix, extracellular space Wnt-protein binding, frizzled binding Human CTIF HPA UniProtKB {GO:0005515=PMID:19648179, GO:0005737=GO_REF:0000052, GO:0048471=PMID:19648179, GO:0000184=PMID:19648179, GO:0003723=GO_REF:0000002, GO:0006446=PMID:19648179, GO:0003677=GO_REF:0000002} O43310 CBP80/20-dependent translation initiation factor protein 20100326 {GO:0005515=IPI, GO:0005737=IDA, GO:0048471=IDA, GO:0000184=IMP, GO:0003723=IEA, GO:0006446=IMP, GO:0003677=IEA} nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, regulation of translational initiation cytoplasm, perinuclear region of cytoplasm DNA binding, RNA binding, protein binding Human CTLA4 BHF-UCL UniProtKB {GO:0050853=PMID:17875758, GO:0005515=PMID:21982860, GO:0048471=PMID:15814706, GO:0043065=PMID:17875758, GO:0005794=PMID:15814706, GO:0005886=Reactome:REACT_19404, GO:0031295=Reactome:REACT_19344, GO:0030889=PMID:17875758, GO:0006974=PMID:17875758, GO:0006955=GO_REF:0000002, GO:0045334=PMID:15814706, GO:0005887=PMID:3220103, GO:0045590=PMID:18641304, GO:0009897=PMID:18641304} P16410 Cytotoxic T-lymphocyte protein 4 protein 20081121 {GO:0050853=IMP, GO:0005515=IPI, GO:0048471=IDA, GO:0043065=IMP, GO:0005794=IDA, GO:0005886=TAS, GO:0031295=TAS, GO:0030889=IMP, GO:0006974=IMP, GO:0006955=IEA, GO:0045334=IDA, GO:0005887=TAS, GO:0045590=IDA, GO:0009897=IDA} B cell receptor signaling pathway, T cell costimulation, immune response, negative regulation of B cell proliferation, negative regulation of regulatory T cell differentiation, positive regulation of apoptotic process, response to DNA damage stimulus Golgi apparatus, clathrin-coated endocytic vesicle, external side of plasma membrane, integral to plasma membrane, perinuclear region of cytoplasm, plasma membrane protein binding Human CTNNA1 ENSEMBL UniProtKB {GO:0005515=PMID:12477722, GO:0031103=GO_REF:0000019, GO:0043627=GO_REF:0000019, GO:0008013=PMID:7650039, GO:0005886=GO_REF:0000019, GO:0016342=PMID:7650039, GO:0016264=GO_REF:0000019, GO:0015629=GO_REF:0000002, GO:0051291=GO_REF:0000019, GO:0007406=GO_REF:0000019, GO:0005829=Reactome:REACT_21371, GO:0042692=Reactome:REACT_21303, GO:0043297=GO_REF:0000019, GO:0005915=GO_REF:0000019, GO:0045880=GO_REF:0000019, GO:0071681=PMID:10868478, GO:0001541=GO_REF:0000019, GO:0051015=GO_REF:0000019, GO:0014704=GO_REF:0000019, GO:0005911=PMID:7650039, GO:0042475=GO_REF:0000019, GO:0007155=GO_REF:0000002, GO:0043066=GO_REF:0000019, GO:0045296=GO_REF:0000002, GO:0045295=PMID:7890674, GO:0001669=GO_REF:0000019, GO:0034329=Reactome:REACT_20676, GO:0007568=GO_REF:0000019, GO:0045216=Reactome:REACT_19331, GO:0030027=GO_REF:0000019, GO:0051149=Reactome:REACT_21402, GO:0007163=GO_REF:0000019, GO:0005198=GO_REF:0000002, GO:0017166=PMID:9700171, GO:0008584=GO_REF:0000019, GO:0034332=Reactome:REACT_19195} Q8N1C0 Catenin alpha 1 isoform CTNNA1b protein 20130413 {GO:0005515=IPI, GO:0031103=IEA, GO:0043627=IEA, GO:0008013=IPI, GO:0005886=IEA, GO:0016342=IDA, GO:0016264=IEA, GO:0015629=IEA, GO:0051291=IEA, GO:0007406=IEA, GO:0005829=TAS, GO:0042692=TAS, GO:0043297=IEA, GO:0005915=IEA, GO:0045880=IEA, GO:0071681=IDA, GO:0001541=IEA, GO:0051015=IEA, GO:0014704=IEA, GO:0005911=IDA, GO:0042475=IEA, GO:0007155=IEA, GO:0043066=IEA, GO:0045296=IEA, GO:0045295=IPI, GO:0001669=IEA, GO:0034329=TAS, GO:0007568=IEA, GO:0045216=TAS, GO:0030027=IEA, GO:0051149=TAS, GO:0007163=IEA, GO:0005198=IEA, GO:0017166=IPI, GO:0008584=IEA, GO:0034332=TAS} adherens junction organization, aging, apical junction assembly, axon regeneration, cell adhesion, cell junction assembly, cell-cell junction organization, cellular response to indole-3-methanol, establishment or maintenance of cell polarity, gap junction assembly, male gonad development, muscle cell differentiation, negative regulation of apoptotic process, negative regulation of neuroblast proliferation, odontogenesis of dentin-containing tooth, ovarian follicle development, positive regulation of muscle cell differentiation, positive regulation of smoothened signaling pathway, protein heterooligomerization, response to estrogen stimulus acrosomal vesicle, actin cytoskeleton, catenin complex, cell-cell junction, cytosol, intercalated disc, lamellipodium, plasma membrane, zonula adherens actin filament binding, beta-catenin binding, cadherin binding, gamma-catenin binding, protein binding, structural molecule activity, vinculin binding Human Ensembl:ENSRNOP00000008041 CTNNA2 Reactome UniProtKB {GO:0005515=PMID:16182284, GO:0030424=GO_REF:0000024, GO:0045296=GO_REF:0000002, GO:0060134=GO_REF:0000024, GO:0007409=GO_REF:0000024, GO:0021942=GO_REF:0000024, GO:0015629=GO_REF:0000002, GO:0030027=GO_REF:0000019, GO:0005829=Reactome:REACT_21371, GO:0048854=GO_REF:0000024, GO:0042692=Reactome:REACT_21303, GO:0016323=GO_REF:0000019, GO:0048813=GO_REF:0000024, GO:0051823=GO_REF:0000024, GO:0016337=GO_REF:0000024, GO:0005737=PMID:16182284, GO:0051149=Reactome:REACT_21402, GO:0005913=GO_REF:0000019, GO:0005912=GO_REF:0000024, GO:0005198=GO_REF:0000002, GO:0005200=PMID:8432524, GO:0007155=GO_REF:0000002} P26232 Catenin alpha-2 protein 20130301 {GO:0005515=IPI, GO:0030424=ISS, GO:0045296=IEA, GO:0060134=ISS, GO:0007409=ISS, GO:0021942=ISS, GO:0015629=IEA, GO:0030027=IEA, GO:0005829=TAS, GO:0048854=ISS, GO:0042692=TAS, GO:0016323=IEA, GO:0048813=ISS, GO:0051823=ISS, GO:0016337=ISS, GO:0005737=IDA, GO:0051149=TAS, GO:0005913=IEA, GO:0005912=ISS, GO:0005198=IEA, GO:0005200=NAS, GO:0007155=IEA} axonogenesis, brain morphogenesis, cell adhesion, cell-cell adhesion, dendrite morphogenesis, muscle cell differentiation, positive regulation of muscle cell differentiation, prepulse inhibition, radial glia guided migration of Purkinje cell, regulation of synapse structural plasticity actin cytoskeleton, adherens junction, axon, basolateral plasma membrane, cell-cell adherens junction, cytoplasm, cytosol, lamellipodium cadherin binding, protein binding, structural constituent of cytoskeleton, structural molecule activity Human CTNNA3 IntAct UniProtKB {GO:0005916=PMID:11590244, GO:0005515=PMID:22190034, GO:0005737=GO_REF:0000037, GO:0016337=PMID:11590244, GO:0045296=PMID:11590244, GO:0005198=GO_REF:0000002, GO:0007155=GO_REF:0000002, GO:0015629=GO_REF:0000002, GO:0030027=GO_REF:0000019} Q9UI47 Catenin alpha-3 protein 20130415 {GO:0005916=IDA, GO:0005515=IPI, GO:0005737=IEA, GO:0016337=IPI, GO:0045296=TAS, GO:0005198=IEA, GO:0007155=IEA, GO:0015629=IEA, GO:0030027=IEA} cell adhesion, cell-cell adhesion actin cytoskeleton, cytoplasm, fascia adherens, lamellipodium cadherin binding, protein binding, structural molecule activity Human UniProtKB:P04591:PRO_0000038596 CTNNAL1 MGI UniProtKB {GO:0045296=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0005198=GO_REF:0000002, GO:0007266=PMID:12270917, GO:0015629=GO_REF:0000002, GO:0007155=GO_REF:0000002, GO:0005829=PMID:12270917} Q9UBT7 Alpha-catulin protein 20091021 {GO:0045296=IEA, GO:0005886=IEA, GO:0005198=IEA, GO:0007266=IDA, GO:0015629=IEA, GO:0007155=IEA, GO:0005829=IDA} Rho protein signal transduction, cell adhesion actin cytoskeleton, cytosol, plasma membrane cadherin binding, structural molecule activity Human CTNNB1 BHF-UCL UniProtKB {GO:0005515=PMID:18287330, GO:0030057=GO_REF:0000033, GO:0043627=GO_REF:0000019, GO:0030054=PMID:19038973, GO:0003700=GO_REF:0000019, GO:0072033=GO_REF:0000033, GO:0044212=PMID:18579517, GO:0045453=GO_REF:0000019, GO:0030877=PMID:16188939, GO:0016342=PMID:20302655, GO:0031528=GO_REF:0000033, GO:0046332=PMID:18593713, GO:0072182=GO_REF:0000024, GO:0048599=GO_REF:0000033, GO:2000008=PMID:19996314, GO:0001711=GO_REF:0000033, GO:0031069=GO_REF:0000033, GO:0060916=GO_REF:0000033, GO:0016337=PMID:18593713, GO:0042129=GO_REF:0000033, GO:0045445=GO_REF:0000019, GO:0016055=PMID:10644691, GO:0001102=PMID:19443654, GO:0071664=GO_REF:0000019, GO:0005813=PMID:20300119, GO:0001708=GO_REF:0000019, GO:0045743=GO_REF:0000033, GO:0003713=PMID:11751639, GO:0001701=GO_REF:0000019, GO:0001702=GO_REF:0000033, GO:0044325=PMID:19996314, GO:0001889=GO_REF:0000033, GO:0000922=GO_REF:0000039, GO:0060440=GO_REF:0000033, GO:0051149=Reactome:REACT_21402, GO:0060441=GO_REF:0000019, GO:0061154=PMID:20123964, GO:0003136=GO_REF:0000033, GO:0043588=GO_REF:0000019, GO:0043587=GO_REF:0000033, GO:0046686=GO_REF:0000019, GO:0008134=PMID:20123964, GO:0051145=GO_REF:0000033, GO:0035315=PMID:19251162, GO:0048471=PMID:19038973, GO:0060066=GO_REF:0000019, GO:0035112=GO_REF:0000019, GO:0044336=PMID:12154096, GO:0048145=PMID:16858403, GO:0005634=PMID:9707618, GO:0001837=PMID:14679171, GO:0051291=GO_REF:0000019, GO:0044334=PMID:17072303, GO:0005829=Reactome:REACT_21371, GO:0014010=GO_REF:0000033, GO:0005916=GO_REF:0000033, GO:0005915=GO_REF:0000033, GO:0043296=GO_REF:0000019, GO:0005913=PMID:20086044, GO:0005912=PMID:16858403, GO:0002089=GO_REF:0000019, GO:0005911=PMID:19996314, GO:0042475=GO_REF:0000033, GO:0048469=GO_REF:0000019, GO:0004871=PMID:10192393, GO:0033234=PMID:22155184, GO:0060070=PMID:19187541, GO:0007016=GO_REF:0000033, GO:0022009=GO_REF:0000033, GO:0003266=GO_REF:0000019, GO:0001569=PMID:20123964, GO:0042493=PMID:18291362, GO:2000017=GO_REF:0000019, GO:0060742=GO_REF:0000019, GO:0045671=GO_REF:0000033, GO:0048660=PMID:17122440, GO:0007398=GO_REF:0000033, GO:0045669=GO_REF:0000033, GO:0003337=GO_REF:0000033, GO:0071363=PMID:16858403, GO:0016020=GO_REF:0000024, GO:0005198=GO_REF:0000033, GO:0034394=PMID:20086044, GO:0007494=GO_REF:0000019, GO:0035116=GO_REF:0000019, GO:0048262=GO_REF:0000033, GO:0030900=GO_REF:0000019, GO:0035115=GO_REF:0000019, GO:0001764=GO_REF:0000019, GO:0030902=GO_REF:0000033, GO:0030018=GO_REF:0000033, GO:0001658=GO_REF:0000033, GO:0045202=GO_REF:0000033, GO:0034750=GO_REF:0000019, GO:0048538=GO_REF:0000033, GO:0050681=PMID:15572661, GO:0072079=GO_REF:0000033, GO:0032403=GO_REF:0000019, GO:0010909=PMID:15853773, GO:0042692=Reactome:REACT_21303, GO:0030539=GO_REF:0000033, GO:0000578=GO_REF:0000033, GO:0003690=GO_REF:0000019, GO:0032993=PMID:10825188, GO:0061047=GO_REF:0000033, GO:0060479=GO_REF:0000033, GO:0043123=GO_REF:0000033, GO:0005938=PMID:19038973, GO:0032355=PMID:15304487, GO:0070602=PMID:20300119, GO:0033077=GO_REF:0000033, GO:0045296=PMID:18287330, GO:0019901=GO_REF:0000033, GO:0045294=PMID:7890674, GO:0019903=PMID:16574648, GO:0030331=PMID:15304487, GO:0048489=GO_REF:0000033, GO:0000122=GO_REF:0000033, GO:0060769=GO_REF:0000033, GO:0001840=GO_REF:0000019, GO:0030027=GO_REF:0000033, GO:0030997=PMID:18086858, GO:0050808=GO_REF:0000033, GO:0009898=GO_REF:0000033, GO:0060484=GO_REF:0000033, GO:0005924=PMID:20399743, GO:0019899=PMID:18356165, GO:0045893=PMID:18787224, GO:0061324=GO_REF:0000024, GO:0061198=GO_REF:0000019, GO:0045892=PMID:19653274, GO:0045603=GO_REF:0000019, GO:0042733=GO_REF:0000019, GO:0008285=PMID:12970740, GO:0005886=GO_REF:0000052, GO:0034333=PMID:20123964, GO:0072054=GO_REF:0000033, GO:0035257=PMID:12799378, GO:0009954=GO_REF:0000033, GO:0030326=GO_REF:0000033, GO:0072053=GO_REF:0000033, GO:0006921=Reactome:REACT_995, GO:0009950=GO_REF:0000033, GO:0071944=PMID:19038973, GO:0036023=GO_REF:0000024, GO:0071681=PMID:10868478, GO:0016323=GO_REF:0000019, GO:0005737=PMID:9707618, GO:0009948=GO_REF:0000019, GO:0043198=GO_REF:0000033, GO:0045944=PMID:15592430, GO:0070491=GO_REF:0000019, GO:0060492=GO_REF:0000033, GO:0031641=GO_REF:0000019, GO:0032331=GO_REF:0000033, GO:0007155=PMID:19101069, GO:0019900=PMID:8638126, GO:0034097=GO_REF:0000019, GO:0005667=PMID:11751639, GO:0043066=PMID:18787224, GO:0043065=PMID:12970740, GO:0035050=GO_REF:0000019, GO:0090279=PMID:19996314, GO:0030316=GO_REF:0000019, GO:0045765=PMID:18756595, GO:0070411=PMID:18593713, GO:0006915=Reactome:REACT_578, GO:0045177=GO_REF:0000019, GO:0002052=GO_REF:0000019, GO:0070412=PMID:20097766, GO:0060789=GO_REF:0000033, GO:0002053=GO_REF:0000019, GO:0008022=PMID:15843474, GO:0016328=PMID:12072559, GO:0006351=GO_REF:0000037, GO:0071407=GO_REF:0000019, GO:0070369=PMID:9065401, GO:0031016=GO_REF:0000033, GO:0007160=GO_REF:0000033, GO:0035255=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0007403=GO_REF:0000033, GO:0048715=GO_REF:0000019, GO:0048617=GO_REF:0000033, GO:0034613=GO_REF:0000019, GO:0043410=GO_REF:0000033, GO:0030521=PMID:15572661} P35222 Catenin beta-1 protein 20100825 {GO:0005515=IPI, GO:0030057=IBA, GO:0043627=IEA, GO:0030054=IDA, GO:0003700=IEA, GO:0072033=IBA, GO:0044212=IDA, GO:0045453=IEA, GO:0030877=IDA, GO:0016342=IDA, GO:0031528=IBA, GO:0046332=IPI, GO:0072182=ISS, GO:0048599=IBA, GO:2000008=IDA, GO:0001711=IBA, GO:0031069=IBA, GO:0060916=IBA, GO:0016337=IMP, GO:0042129=IBA, GO:0045445=IEA, GO:0016055=IDA, GO:0001102=IPI, GO:0071664=IEA, GO:0005813=IDA, GO:0001708=IEA, GO:0045743=IBA, GO:0003713=IDA, GO:0001701=IEA, GO:0001702=IBA, GO:0044325=IPI, GO:0001889=IBA, GO:0000922=IEA, GO:0060440=IBA, GO:0051149=TAS, GO:0060441=IEA, GO:0061154=IMP, GO:0003136=IBA, GO:0043588=IEA, GO:0043587=IBA, GO:0046686=IEA, GO:0008134=IPI, GO:0051145=IBA, GO:0035315=TAS, GO:0048471=IDA, GO:0060066=IEA, GO:0035112=IEA, GO:0044336=IMP, GO:0048145=TAS, GO:0005634=IDA, GO:0001837=TAS, GO:0051291=IEA, GO:0044334=IMP, GO:0005829=TAS, GO:0014010=IBA, GO:0005916=IBA, GO:0005915=IBA, GO:0043296=IEA, GO:0005913=IDA, GO:0005912=IDA, GO:0002089=IEA, GO:0005911=IDA, GO:0042475=IBA, GO:0048469=IEA, GO:0004871=NAS, GO:0033234=IDA, GO:0060070=IDA, GO:0007016=IBA, GO:0022009=IBA, GO:0003266=IEA, GO:0001569=IC, GO:0042493=IEP, GO:2000017=IEA, GO:0060742=IEA, GO:0045671=IBA, GO:0048660=IMP, GO:0007398=IBA, GO:0045669=IBA, GO:0003337=IBA, GO:0071363=IMP, GO:0016020=ISS, GO:0005198=IBA, GO:0034394=IMP, GO:0007494=IEA, GO:0035116=IEA, GO:0048262=IBA, GO:0030900=IEA, GO:0035115=IEA, GO:0001764=IEA, GO:0030902=IBA, GO:0030018=IBA, GO:0001658=IBA, GO:0045202=IBA, GO:0034750=IEA, GO:0048538=IBA, GO:0050681=NAS, GO:0072079=IBA, GO:0032403=IEA, GO:0010909=IMP, GO:0042692=TAS, GO:0030539=IBA, GO:0000578=IBA, GO:0003690=IEA, GO:0032993=IDA, GO:0061047=IBA, GO:0060479=IBA, GO:0043123=IBA, GO:0005938=IDA, GO:0032355=IDA, GO:0070602=IMP, GO:0033077=IBA, GO:0045296=IPI, GO:0019901=IBA, GO:0045294=IPI, GO:0019903=IPI, GO:0030331=IPI, GO:0048489=IBA, GO:0000122=IBA, GO:0060769=IBA, GO:0001840=IEA, GO:0030027=IBA, GO:0030997=IDA, GO:0050808=IBA, GO:0009898=IBA, GO:0060484=IBA, GO:0005924=IDA, GO:0019899=IPI, GO:0045893=IDA, GO:0061324=ISS, GO:0061198=IEA, GO:0045892=IMP, GO:0045603=IEA, GO:0042733=IEA, GO:0008285=IDA, GO:0005886=IDA, GO:0034333=IMP, GO:0072054=IBA, GO:0035257=IPI, GO:0009954=IBA, GO:0030326=IBA, GO:0072053=IBA, GO:0006921=TAS, GO:0009950=IBA, GO:0071944=IDA, GO:0036023=ISS, GO:0071681=IDA, GO:0016323=IEA, GO:0005737=IDA, GO:0009948=IEA, GO:0043198=IBA, GO:0045944=IMP, GO:0070491=IEA, GO:0060492=IBA, GO:0031641=IEA, GO:0032331=IBA, GO:0007155=IMP, GO:0019900=IPI, GO:0034097=IEA, GO:0005667=IDA, GO:0043066=IMP, GO:0043065=IDA, GO:0035050=IEA, GO:0090279=IDA, GO:0030316=IEA, GO:0045765=TAS, GO:0070411=IPI, GO:0006915=TAS, GO:0045177=IEA, GO:0002052=IEA, GO:0070412=IPI, GO:0060789=IBA, GO:0002053=IEA, GO:0008022=IPI, GO:0016328=IDA, GO:0006351=IEA, GO:0071407=IEA, GO:0070369=IDA, GO:0031016=IBA, GO:0007160=IBA, GO:0035255=IEA, GO:0003682=IEA, GO:0007403=IBA, GO:0048715=IEA, GO:0048617=IBA, GO:0034613=IEA, GO:0043410=IBA, GO:0030521=NAS} Schwann cell proliferation, T cell differentiation in thymus, Wnt receptor signaling pathway, adherens junction assembly, androgen receptor signaling pathway, anterior/posterior axis specification, apoptotic process, bone resorption, branching involved in ureteric bud morphogenesis, canonical Wnt receptor signaling pathway, canonical Wnt receptor signaling pathway involved in negative regulation of apoptotic process, canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation, canonical Wnt receptor signaling pathway involved in positive regulation of epithelial to mesenchymal transition, cell adhesion, cell fate specification, cell maturation, cell-cell adhesion, cell-matrix adhesion, cellular component disassembly involved in execution phase of apoptosis, cellular protein localization, cellular response to growth factor stimulus, cellular response to indole-3-methanol, cellular response to organic cyclic compound, central nervous system vasculogenesis, cytoskeletal anchoring at plasma membrane, determination of dorsal/ventral asymmetry, dorsal/ventral axis specification, ectoderm development, embryonic axis specification, embryonic digit morphogenesis, embryonic foregut morphogenesis, embryonic forelimb morphogenesis, embryonic heart tube development, embryonic hindlimb morphogenesis, embryonic limb morphogenesis, embryonic skeletal limb joint morphogenesis, endodermal cell fate commitment, endothelial tube morphogenesis, epithelial cell differentiation involved in prostate gland development, epithelial to mesenchymal transition, epithelial tube branching involved in lung morphogenesis, forebrain development, fungiform papilla formation, gastrulation with mouth forming second, genitalia morphogenesis, glial cell fate determination, hair cell differentiation, hair follicle morphogenesis, hair follicle placode formation, hindbrain development, in utero embryonic development, lens morphogenesis in camera-type eye, liver development, lung cell differentiation, lung induction, lung-associated mesenchyme development, male genitalia development, mesenchymal cell proliferation involved in lung development, mesenchymal to epithelial transition involved in metanephros morphogenesis, midgut development, muscle cell differentiation, myoblast differentiation, negative regulation of apoptotic process, negative regulation of cell proliferation, negative regulation of chondrocyte differentiation, negative regulation of heart induction by canonical Wnt receptor signaling pathway, negative regulation of oligodendrocyte differentiation, negative regulation of osteoclast differentiation, negative regulation of protein sumoylation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, nephron tubule formation, neural plate development, neuron migration, odontogenesis of dentin-containing tooth, oocyte development, osteoclast differentiation, oviduct development, pancreas development, patterning of blood vessels, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of MAPK cascade, positive regulation of apoptotic process, positive regulation of branching involved in lung morphogenesis, positive regulation of determination of dorsal identity, positive regulation of endothelial cell differentiation, positive regulation of epithelial cell proliferation involved in prostate gland development, positive regulation of fibroblast growth factor receptor signaling pathway, positive regulation of heparan sulfate proteoglycan biosynthetic process, positive regulation of mesenchymal cell proliferation, positive regulation of muscle cell differentiation, positive regulation of neuroblast proliferation, positive regulation of osteoblast differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein heterooligomerization, protein localization to cell surface, proximal/distal pattern formation, regulation of T cell proliferation, regulation of angiogenesis, regulation of calcium ion import, regulation of centriole-centriole cohesion, regulation of centromeric sister chromatid cohesion, regulation of fibroblast proliferation, regulation of myelination, regulation of nephron tubule epithelial cell differentiation, regulation of protein localization to cell surface, regulation of secondary heart field cardioblast proliferation, regulation of smooth muscle cell proliferation, renal inner medulla development, renal outer medulla development, renal vesicle formation, response to cadmium ion, response to cytokine stimulus, response to drug, response to estradiol stimulus, response to estrogen stimulus, skin development, smooth muscle cell differentiation, synapse organization, synaptic vesicle transport, thymus development, tongue morphogenesis, trachea formation, transcription, DNA-dependent Scrib-APC-beta-catenin complex, Z disc, adherens junction, apical junction complex, apical part of cell, basolateral plasma membrane, beta-catenin destruction complex, beta-catenin-TCF7L2 complex, catenin complex, catenin-TCF7L2 complex, cell cortex, cell junction, cell periphery, cell-cell adherens junction, cell-cell junction, cell-substrate adherens junction, centrosome, cytoplasm, cytosol, dendritic shaft, desmosome, fascia adherens, internal side of plasma membrane, lamellipodium, lateral plasma membrane, membrane, microvillus membrane, nucleus, perinuclear region of cytoplasm, plasma membrane, protein-DNA complex, spindle pole, synapse, transcription factor complex, zonula adherens I-SMAD binding, R-SMAD binding, RNA polymerase II activating transcription factor binding, SMAD binding, alpha-catenin binding, androgen receptor binding, cadherin binding, chromatin binding, double-stranded DNA binding, enzyme binding, estrogen receptor binding, ion channel binding, ionotropic glutamate receptor binding, kinase binding, nuclear hormone receptor binding, protein C-terminus binding, protein binding, protein complex binding, protein kinase binding, protein phosphatase binding, repressing transcription factor binding, sequence-specific DNA binding transcription factor activity, signal transducer activity, structural molecule activity, transcription coactivator activity, transcription factor binding, transcription regulatory region DNA binding Human CTNNBIP1 BHF-UCL UniProtKB {GO:0002528=PMID:18287330, GO:0005515=PMID:21885566, GO:0032091=PMID:18287330, GO:0072201=PMID:18977368, GO:0001658=GO_REF:0000033, GO:0008013=PMID:18287330, GO:0030178=GO_REF:0000033, GO:0030877=PMID:16188939, GO:0005634=PMID:19569129, GO:0048662=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0009952=GO_REF:0000033, GO:0043433=PMID:18977368, GO:0005829=PMID:18287330, GO:0043392=GO_REF:0000019, GO:0045669=PMID:18977368, GO:0060633=GO_REF:0000019, GO:0005737=PMID:19569129, GO:0045657=PMID:19569129, GO:0016055=GO_REF:0000019, GO:0070016=PMID:12408825} Q9NSA3 Beta-catenin-interacting protein 1 protein 20100722 {GO:0002528=IMP, GO:0005515=IPI, GO:0032091=IDA, GO:0072201=IMP, GO:0001658=IBA, GO:0008013=IPI, GO:0030178=IBA, GO:0030877=IDA, GO:0005634=IDA, GO:0048662=IEA, GO:0000122=IEA, GO:0009952=IBA, GO:0043433=IMP, GO:0005829=IDA, GO:0043392=IEA, GO:0045669=IMP, GO:0060633=IEA, GO:0005737=IDA, GO:0045657=IMP, GO:0016055=IEA, GO:0070016=IPI} Wnt receptor signaling pathway, anterior/posterior pattern specification, branching involved in ureteric bud morphogenesis, negative regulation of DNA binding, negative regulation of Wnt receptor signaling pathway, negative regulation of mesenchymal cell proliferation, negative regulation of protein binding, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of smooth muscle cell proliferation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription initiation from RNA polymerase II promoter, positive regulation of monocyte differentiation, positive regulation of osteoblast differentiation, regulation of vascular permeability involved in acute inflammatory response beta-catenin destruction complex, cytoplasm, cytosol, nucleus armadillo repeat domain binding, beta-catenin binding, protein binding Human CTNNBL1 HPA UniProtKB {GO:0000974=PMID:15175653, GO:0005515=PMID:20176811, GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0043065=PMID:12659813, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0005681=PMID:20176811, GO:0016445=PMID:18722174, GO:0005634=GO_REF:0000052, GO:0019899=PMID:18722174} Q8WYA6 Beta-catenin-like protein 1 protein 20080818 {GO:0000974=IDA, GO:0005515=IPI, GO:0008380=IEA, GO:0006397=IEA, GO:0043065=IDA, GO:0005730=IDA, GO:0006915=IEA, GO:0005681=IDA, GO:0016445=IMP, GO:0005634=IDA, GO:0019899=IPI} RNA splicing, apoptotic process, mRNA processing, positive regulation of apoptotic process, somatic diversification of immunoglobulins Prp19 complex, nucleolus, nucleus, spliceosomal complex enzyme binding, protein binding NOT Human CTNND1 BHF-UCL UniProtKB {GO:0005515=PMID:20123964, GO:0060690=GO_REF:0000019, GO:0005886=PMID:20123964, GO:0005634=PMID:20123964, GO:0001738=GO_REF:0000019, GO:0005829=PMID:20123964, GO:0016337=GO_REF:0000019, GO:0005737=PMID:17047063, GO:0005913=GO_REF:0000019, GO:0005911=PMID:12370829, GO:0016055=GO_REF:0000037, GO:0007155=PMID:8808291, GO:0090090=PMID:20123964, GO:0007435=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0045296=PMID:12734196, GO:0019903=GO_REF:0000019, GO:0034329=Reactome:REACT_20676, GO:0019904=GO_REF:0000019, GO:0005102=PMID:19332538, GO:0030496=PMID:15166316, GO:0006351=GO_REF:0000037, GO:0030027=GO_REF:0000019, GO:0045216=Reactome:REACT_19331, GO:0030216=GO_REF:0000019, GO:0034332=Reactome:REACT_19195} O60716 Catenin delta-1 protein 20100721 {GO:0005515=IPI, GO:0060690=IEA, GO:0005886=IMP, GO:0005634=IDA, GO:0001738=IEA, GO:0005829=IMP, GO:0016337=IEA, GO:0005737=IDA, GO:0005913=IEA, GO:0005911=IDA, GO:0016055=IEA, GO:0007155=NAS, GO:0090090=IMP, GO:0007435=IEA, GO:0006355=IEA, GO:0045296=IPI, GO:0019903=IEA, GO:0034329=TAS, GO:0019904=IEA, GO:0005102=IPI, GO:0030496=IDA, GO:0006351=IEA, GO:0030027=IEA, GO:0045216=TAS, GO:0030216=IEA, GO:0034332=TAS} Wnt receptor signaling pathway, adherens junction organization, cell adhesion, cell junction assembly, cell-cell adhesion, cell-cell junction organization, epithelial cell differentiation involved in salivary gland development, keratinocyte differentiation, morphogenesis of a polarized epithelium, negative regulation of canonical Wnt receptor signaling pathway, regulation of transcription, DNA-dependent, salivary gland morphogenesis, transcription, DNA-dependent cell-cell adherens junction, cell-cell junction, cytoplasm, cytosol, lamellipodium, midbody, nucleus, plasma membrane cadherin binding, protein binding, protein domain specific binding, protein phosphatase binding, receptor binding Human CTNND2 PINC UniProtKB {GO:0005515=PMID:19706687, GO:0006355=GO_REF:0000037, GO:0007275=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037, GO:0007165=PMID:9223106, GO:0005737=PMID:9342840, GO:0005912=GO_REF:0000039, GO:0048167=GO_REF:0000019, GO:0043204=GO_REF:0000039, GO:0007612=GO_REF:0000019, GO:0007155=PMID:9223106, GO:0001763=GO_REF:0000019, GO:0007158=GO_REF:0000029} Q9UQB3 Catenin delta-2 protein 20050308 {GO:0005515=IPI, GO:0006355=IEA, GO:0007275=IEA, GO:0005634=IEA, GO:0006351=IEA, GO:0007165=TAS, GO:0005737=TAS, GO:0005912=IEA, GO:0048167=IEA, GO:0043204=IEA, GO:0007612=IEA, GO:0007155=TAS, GO:0001763=IEA, GO:0007158=NAS} cell adhesion, learning, morphogenesis of a branching structure, multicellular organismal development, neuron cell-cell adhesion, regulation of synaptic plasticity, regulation of transcription, DNA-dependent, signal transduction, transcription, DNA-dependent adherens junction, cytoplasm, nucleus, perikaryon protein binding Human CTPS2 Reactome UniProtKB {GO:0005739=GO_REF:0000019, GO:0015949=Reactome:REACT_21330, GO:0055086=Reactome:REACT_1698, GO:0006221=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0006220=PMID:10899599, GO:0044210=GO_REF:0000041, GO:0005524=GO_REF:0000037, GO:0003883=Reactome:REACT_21305, GO:0005829=Reactome:REACT_21305, GO:0006541=GO_REF:0000037} Q9NRF8 CTP synthase 2 protein 20130213 {GO:0005739=IEA, GO:0015949=TAS, GO:0055086=TAS, GO:0006221=IEA, GO:0044281=TAS, GO:0006220=TAS, GO:0044210=IEA, GO:0005524=IEA, GO:0003883=EXP, GO:0005829=TAS, GO:0006541=IEA} 'de novo' CTP biosynthetic process, glutamine metabolic process, nucleobase-containing small molecule interconversion, nucleobase-containing small molecule metabolic process, pyrimidine nucleotide biosynthetic process, pyrimidine nucleotide metabolic process, small molecule metabolic process cytosol, mitochondrion ATP binding, CTP synthase activity Human CTR9 IntAct UniProtKB {GO:0005515=PMID:20541477, GO:0033523=PMID:16307923, GO:0080182=PMID:16024656, GO:0035327=GO_REF:0000024, GO:0000122=GO_REF:0000024, GO:0007259=GO_REF:0000024, GO:0001711=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0071222=GO_REF:0000024, GO:0051571=PMID:16024656, GO:0016607=GO_REF:0000039, GO:0045638=PMID:20541477, GO:0045944=PMID:20178742, GO:0019827=PMID:19345177, GO:0032968=PMID:20178742, GO:2001162=PMID:16024656, GO:0016593=PMID:20178742, GO:0070102=GO_REF:0000024, GO:0016055=GO_REF:0000037, GO:0042169=GO_REF:0000019, GO:0010390=PMID:16307923} Q6PD62 RNA polymerase-associated protein CTR9 homolog protein 20130415 {GO:0005515=IPI, GO:0033523=IDA, GO:0080182=IMP, GO:0035327=ISS, GO:0000122=ISS, GO:0007259=ISS, GO:0001711=ISS, GO:0006351=IEA, GO:0071222=ISS, GO:0051571=IMP, GO:0016607=IEA, GO:0045638=IDA, GO:0045944=IDA, GO:0019827=IDA, GO:0032968=IDA, GO:2001162=IMP, GO:0016593=IDA, GO:0070102=ISS, GO:0016055=IEA, GO:0042169=IEA, GO:0010390=IDA} JAK-STAT cascade, Wnt receptor signaling pathway, cellular response to lipopolysaccharide, endodermal cell fate commitment, histone H2B ubiquitination, histone H3-K4 trimethylation, histone monoubiquitination, interleukin-6-mediated signaling pathway, negative regulation of myeloid cell differentiation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of histone H3-K4 methylation, positive regulation of histone H3-K79 methylation, positive regulation of transcription elongation from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter, stem cell maintenance, transcription, DNA-dependent Cdc73/Paf1 complex, nuclear speck, transcriptionally active chromatin SH2 domain binding, protein binding Human UniProtKB:Q03164 CTRB1 Reactome UniProtKB {GO:0022617=Reactome:REACT_118572, GO:0004252=PMID:2917002, GO:0030198=Reactome:REACT_118779, GO:0007586=GO_REF:0000037, GO:0006508=GO_REF:0000029, GO:0005576=Reactome:REACT_118776, GO:0005615=GO_REF:0000039} P17538 Chymotrypsinogen B protein 20130213 {GO:0022617=TAS, GO:0004252=NAS, GO:0030198=TAS, GO:0007586=IEA, GO:0006508=NAS, GO:0005576=TAS, GO:0005615=IEA} digestion, extracellular matrix disassembly, extracellular matrix organization, proteolysis extracellular region, extracellular space serine-type endopeptidase activity Human CTRC PINC UniProtKB {GO:0004252=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0008233=PMID:8635596} Q99895 Chymotrypsin-C protein 20030904 {GO:0004252=IEA, GO:0006508=IEA, GO:0008233=TAS} proteolysis peptidase activity, serine-type endopeptidase activity Human CTRL PINC UniProtKB {GO:0004252=GO_REF:0000002, GO:0007586=PMID:9065485, GO:0006508=GO_REF:0000019, GO:0005615=PMID:9065485} P40313 Chymotrypsin-like protease CTRL-1 protein 20030904 {GO:0004252=IEA, GO:0007586=TAS, GO:0006508=IEA, GO:0005615=TAS} digestion, proteolysis extracellular space serine-type endopeptidase activity Human CTSA InterPro UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0006687=Reactome:REACT_116105, GO:0005783=PMID:1387645, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0043085=PMID:3107551, GO:0005764=PMID:3136930, GO:0006886=PMID:1387645, GO:0043231=GO_REF:0000052, GO:0005739=GO_REF:0000019, GO:0004185=GO_REF:0000002, GO:0006508=GO_REF:0000002, GO:0004180=PMID:2244901, GO:0008047=PMID:3107551, GO:0043202=Reactome:REACT_116118} Q5JZH0 Lysosomal protective protein 20 kDa chain protein 20130413 {GO:0006665=TAS, GO:0006687=TAS, GO:0005783=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0043085=TAS, GO:0005764=NAS, GO:0006886=TAS, GO:0043231=IDA, GO:0005739=IEA, GO:0004185=IEA, GO:0006508=IEA, GO:0004180=TAS, GO:0008047=TAS, GO:0043202=TAS} glycosphingolipid metabolic process, intracellular protein transport, positive regulation of catalytic activity, proteolysis, small molecule metabolic process, sphingolipid metabolic process endoplasmic reticulum, intracellular membrane-bounded organelle, lysosomal lumen, lysosome, mitochondrion, nucleolus, nucleus carboxypeptidase activity, enzyme activator activity, serine-type carboxypeptidase activity Human InterPro:IPR001563|InterPro:IPR018202 CTSB HPA UniProtKB {GO:0005515=PMID:6203523, GO:0042470=GO_REF:0000039, GO:0048471=PMID:15614436, GO:0005730=GO_REF:0000052, GO:0005576=Reactome:REACT_150437, GO:0042981=PMID:16130169, GO:0002224=Reactome:REACT_6966, GO:0005615=PMID:22261194, GO:0005764=GO_REF:0000019, GO:0043231=GO_REF:0000052, GO:0004197=PMID:6203523, GO:0005739=GO_REF:0000019, GO:0005622=PMID:1645961, GO:0050790=GO_REF:0000002, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0045087=Reactome:REACT_6802, GO:0036021=Reactome:REACT_118824, GO:0030574=Reactome:REACT_150401, GO:0006508=PMID:7890620, GO:0008233=PMID:7890620} P07858 Cathepsin B protein 20120912 {GO:0005515=IPI, GO:0042470=IEA, GO:0048471=IDA, GO:0005730=IDA, GO:0005576=TAS, GO:0042981=TAS, GO:0002224=TAS, GO:0005615=ISS, GO:0005764=IEA, GO:0043231=IDA, GO:0004197=IDA, GO:0005739=IEA, GO:0005622=TAS, GO:0050790=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0045087=TAS, GO:0036021=TAS, GO:0030574=TAS, GO:0006508=IDA, GO:0008233=IDA} collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, innate immune response, proteolysis, regulation of apoptotic process, regulation of catalytic activity, toll-like receptor signaling pathway endolysosome lumen, extracellular region, extracellular space, intracellular, intracellular membrane-bounded organelle, lysosome, melanosome, mitochondrion, nucleolus, perinuclear region of cytoplasm cysteine-type endopeptidase activity, peptidase activity, protein binding Human CTSC PINC UniProtKB {GO:0031404=GO_REF:0000019, GO:0005794=GO_REF:0000019, GO:0010033=GO_REF:0000019, GO:0004252=GO_REF:0000019, GO:0005783=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0043621=GO_REF:0000019, GO:0005764=PMID:7665576, GO:0042802=GO_REF:0000019, GO:0006955=PMID:9092576, GO:0001913=GO_REF:0000019, GO:0006508=GO_REF:0000002, GO:0008234=GO_REF:0000002} P53634 Dipeptidyl peptidase 1 protein 20030904 {GO:0031404=IEA, GO:0005794=IEA, GO:0010033=IEA, GO:0004252=IEA, GO:0005783=IEA, GO:0007568=IEA, GO:0043621=IEA, GO:0005764=TAS, GO:0042802=IEA, GO:0006955=TAS, GO:0001913=IEA, GO:0006508=IEA, GO:0008234=IEA} T cell mediated cytotoxicity, aging, immune response, proteolysis, response to organic substance Golgi apparatus, endoplasmic reticulum, lysosome chloride ion binding, cysteine-type peptidase activity, identical protein binding, protein self-association, serine-type endopeptidase activity Human CTSD BHF-UCL UniProtKB {GO:0008219=GO_REF:0000037, GO:0042470=GO_REF:0000039, GO:0005576=Reactome:REACT_150386, GO:0005615=PMID:22261194, GO:0005764=PMID:19723497, GO:0005739=GO_REF:0000019, GO:0019886=Reactome:REACT_121399, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0006508=GO_REF:0000037, GO:0004190=GO_REF:0000019, GO:0000045=GO_REF:0000019, GO:0043202=Reactome:REACT_121107} P07339 Cathepsin D protein 20120228 {GO:0008219=IEA, GO:0042470=IEA, GO:0005576=TAS, GO:0005615=ISS, GO:0005764=IDA, GO:0005739=IEA, GO:0019886=TAS, GO:0022617=TAS, GO:0030198=TAS, GO:0030574=TAS, GO:0006508=IEA, GO:0004190=IEA, GO:0000045=IEA, GO:0043202=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, autophagic vacuole assembly, cell death, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, proteolysis extracellular region, extracellular space, lysosomal lumen, lysosome, melanosome, mitochondrion aspartic-type endopeptidase activity Human UniProtKB:P00795 CTSE PINC UniProtKB {GO:0019886=PMID:8765029, GO:0016540=GO_REF:0000019, GO:0007586=PMID:2674141, GO:0006508=GO_REF:0000037, GO:0004190=PMID:7789521, GO:0042803=GO_REF:0000019, GO:0005768=PMID:7983070} P14091 Cathepsin E protein 20030904 {GO:0019886=IDA, GO:0016540=IEA, GO:0007586=TAS, GO:0006508=IEA, GO:0004190=IDA, GO:0042803=IEA, GO:0005768=IDA} antigen processing and presentation of exogenous peptide antigen via MHC class II, digestion, protein autoprocessing, proteolysis endosome aspartic-type endopeptidase activity, protein homodimerization activity Human CTSF Reactome UniProtKB {GO:0004197=PMID:9822672, GO:0019886=Reactome:REACT_121399, GO:0006508=GO_REF:0000037, GO:0008234=GO_REF:0000002, GO:0005764=PMID:9822672, GO:0043202=Reactome:REACT_121107} Q9UBX1 Cathepsin F protein 20110201 {GO:0004197=TAS, GO:0019886=TAS, GO:0006508=IEA, GO:0008234=IEA, GO:0005764=TAS, GO:0043202=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, proteolysis lysosomal lumen, lysosome cysteine-type endopeptidase activity, cysteine-type peptidase activity Human CTSG Reactome UniProtKB {GO:0002003=Reactome:REACT_147707, GO:0009986=GO_REF:0000039, GO:0005886=Reactome:REACT_147744, GO:0004252=PMID:8194606, GO:0050832=GO_REF:0000019, GO:0005576=Reactome:REACT_118608, GO:0006955=PMID:2569462, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0050778=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0006508=PMID:11907569, GO:0008233=PMID:11907569, GO:0044130=GO_REF:0000019, GO:0030141=PMID:11907569, GO:0044267=Reactome:REACT_17015, GO:0008201=PMID:11907569, GO:0070946=GO_REF:0000019} P08311 Cathepsin G protein 20130301 {GO:0002003=TAS, GO:0009986=IEA, GO:0005886=TAS, GO:0004252=IDA, GO:0050832=IEA, GO:0005576=TAS, GO:0006955=TAS, GO:0022617=TAS, GO:0030198=TAS, GO:0050778=IEA, GO:0032496=IEA, GO:0006508=IDA, GO:0008233=IDA, GO:0044130=IEA, GO:0030141=IDA, GO:0044267=TAS, GO:0008201=IDA, GO:0070946=IEA} angiotensin maturation, cellular protein metabolic process, defense response to fungus, extracellular matrix disassembly, extracellular matrix organization, immune response, negative regulation of growth of symbiont in host, neutrophil mediated killing of gram-positive bacterium, positive regulation of immune response, proteolysis, response to lipopolysaccharide cell surface, extracellular region, plasma membrane, secretory granule heparin binding, peptidase activity, serine-type endopeptidase activity Human CTSH BHF-UCL UniProtKB {GO:0001656=GO_REF:0000024, GO:0005515=PMID:6203523, GO:0030984=GO_REF:0000019, GO:0008284=GO_REF:0000024, GO:0097067=GO_REF:0000019, GO:0004252=GO_REF:0000024, GO:0010813=PMID:15127951, GO:0010815=PMID:15127951, GO:0007283=GO_REF:0000019, GO:0043621=GO_REF:0000019, GO:0070324=PMID:21217776, GO:0005615=PMID:9050938, GO:0032403=GO_REF:0000019, GO:0031648=PMID:17500053, GO:0019882=PMID:15196205, GO:0033619=GO_REF:0000019, GO:0006508=PMID:6203523, GO:0043129=PMID:18216060, GO:0032526=GO_REF:0000024, GO:0070371=PMID:21217776, GO:0030108=PMID:16822283, GO:0043066=GO_REF:0000024, GO:0001669=GO_REF:0000019, GO:0001520=GO_REF:0000019, GO:0045766=GO_REF:0000024, GO:0002250=PMID:15196205, GO:0004197=PMID:6203523, GO:0010952=PMID:20435891, GO:0016505=PMID:20435891, GO:0004175=PMID:14766755, GO:0001913=GO_REF:0000024, GO:0002764=PMID:16822283, GO:0004177=GO_REF:0000019, GO:0008233=PMID:18216060, GO:0060448=GO_REF:0000024, GO:0010634=GO_REF:0000024, GO:0031638=GO_REF:0000019} P09668 Pro-cathepsin H protein 20080810 {GO:0001656=ISS, GO:0005515=IPI, GO:0030984=IEA, GO:0008284=ISS, GO:0097067=IEA, GO:0004252=ISS, GO:0010813=IDA, GO:0010815=IDA, GO:0007283=IEA, GO:0043621=IEA, GO:0070324=IDA, GO:0005615=IDA, GO:0032403=IEA, GO:0031648=IMP, GO:0019882=TAS, GO:0033619=IEA, GO:0006508=IDA, GO:0043129=IDA, GO:0032526=ISS, GO:0070371=IDA, GO:0030108=IDA, GO:0043066=ISS, GO:0001669=IEA, GO:0001520=IEA, GO:0045766=ISS, GO:0002250=IEP, GO:0004197=IDA, GO:0010952=IDA, GO:0016505=IDA, GO:0004175=IDA, GO:0001913=ISS, GO:0002764=IDA, GO:0004177=IEA, GO:0008233=IDA, GO:0060448=ISS, GO:0010634=ISS, GO:0031638=IEA} ERK1 and ERK2 cascade, T cell mediated cytotoxicity, adaptive immune response, antigen processing and presentation, bradykinin catabolic process, cellular response to thyroid hormone stimulus, dichotomous subdivision of terminal units involved in lung branching, immune response-regulating signaling pathway, membrane protein proteolysis, metanephros development, negative regulation of apoptotic process, neuropeptide catabolic process, positive regulation of angiogenesis, positive regulation of cell proliferation, positive regulation of epithelial cell migration, positive regulation of peptidase activity, protein destabilization, proteolysis, response to retinoic acid, spermatogenesis, surfactant homeostasis, zymogen activation acrosomal vesicle, extracellular space, outer dense fiber HLA-A specific activating MHC class I receptor activity, aminopeptidase activity, apoptotic protease activator activity, cysteine-type endopeptidase activity, endopeptidase activity, kininogen binding, peptidase activity, protein binding, protein complex binding, protein self-association, serine-type endopeptidase activity, thyroid hormone binding Human UniProtKB:P01034 CTSK InterPro UniProtKB {GO:0045453=GO_REF:0000019, GO:0005576=Reactome:REACT_150437, GO:0002224=Reactome:REACT_6966, GO:0005615=GO_REF:0000019, GO:0004197=PMID:9143502, GO:0001957=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0036021=Reactome:REACT_118824, GO:0045087=Reactome:REACT_6802, GO:0030574=Reactome:REACT_150401, GO:0006508=GO_REF:0000002, GO:0008234=GO_REF:0000002} Q5QP40 Cathepsin K protein 20130413 {GO:0045453=IEA, GO:0005576=TAS, GO:0002224=TAS, GO:0005615=IEA, GO:0004197=TAS, GO:0001957=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0036021=TAS, GO:0045087=TAS, GO:0030574=TAS, GO:0006508=IEA, GO:0008234=IEA} bone resorption, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, innate immune response, intramembranous ossification, proteolysis, toll-like receptor signaling pathway endolysosome lumen, extracellular region, extracellular space cysteine-type endopeptidase activity, cysteine-type peptidase activity Human InterPro:IPR000668|InterPro:IPR013128|InterPro:IPR015644 CTSL1 InterPro UniProtKB {GO:0005515=PMID:17889653, GO:0005634=PMID:21326229, GO:0005576=Reactome:REACT_150437, GO:0002224=Reactome:REACT_6966, GO:0005764=GO_REF:0000029, GO:0071888=PMID:18495127, GO:0002250=PMID:15196205, GO:0004197=PMID:14511383, GO:0042393=PMID:21326229, GO:0019886=Reactome:REACT_121399, GO:0022617=Reactome:REACT_118572, GO:0019882=PMID:15196205, GO:0030198=Reactome:REACT_118779, GO:0036021=Reactome:REACT_118824, GO:0045087=Reactome:REACT_6802, GO:0030574=Reactome:REACT_150401, GO:0006508=GO_REF:0000002, GO:0008234=GO_REF:0000002, GO:0043202=Reactome:REACT_121107} Q5T8F0 Cathepsin L1 light chain protein 20130413 {GO:0005515=IPI, GO:0005634=TAS, GO:0005576=TAS, GO:0002224=TAS, GO:0005764=NAS, GO:0071888=NAS, GO:0002250=IEP, GO:0004197=IDA, GO:0042393=IDA, GO:0019886=TAS, GO:0022617=TAS, GO:0019882=TAS, GO:0030198=TAS, GO:0036021=TAS, GO:0045087=TAS, GO:0030574=TAS, GO:0006508=IEA, GO:0008234=IEA, GO:0043202=TAS} adaptive immune response, antigen processing and presentation, antigen processing and presentation of exogenous peptide antigen via MHC class II, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, innate immune response, macrophage apoptotic process, proteolysis, toll-like receptor signaling pathway endolysosome lumen, extracellular region, lysosomal lumen, lysosome, nucleus cysteine-type endopeptidase activity, cysteine-type peptidase activity, histone binding, protein binding Human InterPro:IPR000668|InterPro:IPR013128 CTSL2 Reactome UniProtKB {GO:0030984=GO_REF:0000019, GO:0043005=GO_REF:0000019, GO:0048102=GO_REF:0000019, GO:0021675=GO_REF:0000019, GO:0010259=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0046697=GO_REF:0000019, GO:0019886=Reactome:REACT_121399, GO:0060008=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0006508=GO_REF:0000019, GO:0043204=GO_REF:0000019, GO:0043202=Reactome:REACT_121107, GO:0009267=GO_REF:0000019, GO:0042277=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0005576=Reactome:REACT_118765, GO:0034698=GO_REF:0000019, GO:0009749=GO_REF:0000019, GO:0004197=GO_REF:0000019, GO:0005902=GO_REF:0000019, GO:0004177=GO_REF:0000019, GO:0008234=PMID:9563472, GO:0009897=GO_REF:0000019} O60911 Cathepsin L2 protein 20110201 {GO:0030984=IEA, GO:0043005=IEA, GO:0048102=IEA, GO:0021675=IEA, GO:0010259=IEA, GO:0007283=IEA, GO:0032403=IEA, GO:0046697=IEA, GO:0019886=TAS, GO:0060008=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0006508=IEA, GO:0043204=IEA, GO:0043202=TAS, GO:0009267=IEA, GO:0042277=IEA, GO:0051384=IEA, GO:0005576=TAS, GO:0034698=IEA, GO:0009749=IEA, GO:0004197=IEA, GO:0005902=IEA, GO:0004177=IEA, GO:0008234=TAS, GO:0009897=IEA} Sertoli cell differentiation, antigen processing and presentation of exogenous peptide antigen via MHC class II, autophagic cell death, cellular response to starvation, decidualization, extracellular matrix disassembly, extracellular matrix organization, multicellular organismal aging, nerve development, proteolysis, response to glucocorticoid stimulus, response to glucose stimulus, response to gonadotropin stimulus, spermatogenesis external side of plasma membrane, extracellular region, lysosomal lumen, microvillus, neuron projection, perikaryon aminopeptidase activity, cysteine-type endopeptidase activity, cysteine-type peptidase activity, kininogen binding, peptide binding, protein complex binding Human CTSO PINC UniProtKB {GO:0004197=PMID:7929457, GO:0006508=GO_REF:0000037, GO:0005764=GO_REF:0000039} P43234 Cathepsin O protein 20030904 {GO:0004197=TAS, GO:0006508=IEA, GO:0005764=IEA} proteolysis lysosome cysteine-type endopeptidase activity Human CTSS HPA UniProtKB {GO:0002474=Reactome:REACT_75820, GO:0002480=Reactome:REACT_111168, GO:0042590=Reactome:REACT_111119, GO:0005576=PMID:14718574, GO:0002224=Reactome:REACT_6966, GO:0005764=GO_REF:0000029, GO:0043231=GO_REF:0000052, GO:0002250=PMID:15196205, GO:0004197=PMID:1373132, GO:0019886=Reactome:REACT_121399, GO:0006955=PMID:8157683, GO:0016020=GO_REF:0000019, GO:0019882=PMID:15196205, GO:0045087=Reactome:REACT_6802, GO:0036021=Reactome:REACT_118824, GO:0006508=GO_REF:0000019, GO:0043202=Reactome:REACT_121306} P25774 Cathepsin S protein 20101115 {GO:0002474=TAS, GO:0002480=TAS, GO:0042590=TAS, GO:0005576=NAS, GO:0002224=TAS, GO:0005764=NAS, GO:0043231=IDA, GO:0002250=IEP, GO:0004197=TAS, GO:0019886=TAS, GO:0006955=TAS, GO:0016020=IEA, GO:0019882=TAS, GO:0045087=TAS, GO:0036021=TAS, GO:0006508=IEA, GO:0043202=TAS} adaptive immune response, antigen processing and presentation, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent, antigen processing and presentation of exogenous peptide antigen via MHC class II, antigen processing and presentation of peptide antigen via MHC class I, immune response, innate immune response, proteolysis, toll-like receptor signaling pathway endolysosome lumen, extracellular region, intracellular membrane-bounded organelle, lysosomal lumen, lysosome, membrane cysteine-type endopeptidase activity Human CTSW PINC UniProtKB {GO:0006955=PMID:9823953, GO:0006508=GO_REF:0000037, GO:0008234=GO_REF:0000037} P56202 Cathepsin W protein 20030904 {GO:0006955=TAS, GO:0006508=IEA, GO:0008234=IEA} immune response, proteolysis cysteine-type peptidase activity Human CTSZ Reactome UniProtKB {GO:0060441=GO_REF:0000019, GO:0005886=Reactome:REACT_147799, GO:0002003=Reactome:REACT_147707, GO:0005783=GO_REF:0000054, GO:0006508=GO_REF:0000037, GO:0008234=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0005764=GO_REF:0000039} Q9UBR2 Cathepsin Z protein 20130301 {GO:0060441=IEA, GO:0005886=TAS, GO:0002003=TAS, GO:0005783=IDA, GO:0006508=IEA, GO:0008234=IEA, GO:0044267=TAS, GO:0005764=IEA} angiotensin maturation, cellular protein metabolic process, epithelial tube branching involved in lung morphogenesis, proteolysis endoplasmic reticulum, lysosome, plasma membrane cysteine-type peptidase activity Human CTTN BHF-UCL UniProtKB {GO:0005515=PMID:19146815, GO:0005737=PMID:10760273, GO:0043197=GO_REF:0000039, GO:0005856=GO_REF:0000039, GO:0005938=GO_REF:0000024, GO:0001726=GO_REF:0000024, GO:0030027=PMID:10760273} Q14247 Src substrate cortactin protein 20110112 {GO:0005515=IPI, GO:0005737=IDA, GO:0043197=IEA, GO:0005856=IEA, GO:0005938=ISS, GO:0001726=ISS, GO:0030027=IDA} cell cortex, cytoplasm, cytoskeleton, dendritic spine, lamellipodium, ruffle protein binding Human CTTNBP2 UniProtKB UniProtKB {GO:0017124=GO_REF:0000019, GO:0043197=GO_REF:0000039, GO:0007420=GO_REF:0000019, GO:0005938=GO_REF:0000039, GO:0008021=GO_REF:0000019} Q8WZ74 Cortactin-binding protein 2 protein 20130413 {GO:0017124=IEA, GO:0043197=IEA, GO:0007420=IEA, GO:0005938=IEA, GO:0008021=IEA} brain development cell cortex, dendritic spine, synaptic vesicle SH3 domain binding Human UniProtKB-SubCell:SL-0284 CTTNBP2NL IntAct UniProtKB {GO:0005515=PMID:23455922, GO:0005737=GO_REF:0000037, GO:0015629=GO_REF:0000054} Q9P2B4 CTTNBP2 N-terminal-like protein protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0015629=IDA} actin cytoskeleton, cytoplasm protein binding Human UniProtKB:Q9Y6E0 CTU1 UniProtKB UniProtKB {GO:0005515=PMID:19017811, GO:0002098=PMID:19017811, GO:0005739=GO_REF:0000019, GO:0000049=GO_REF:0000037, GO:0034227=PMID:19017811, GO:0005524=GO_REF:0000002, GO:0016740=GO_REF:0000037, GO:0005829=GO_REF:0000024} Q7Z7A3 Cytoplasmic tRNA 2-thiolation protein 1 protein 20090529 {GO:0005515=IPI, GO:0002098=NAS, GO:0005739=IEA, GO:0000049=IEA, GO:0034227=NAS, GO:0005524=IEA, GO:0016740=IEA, GO:0005829=ISS} tRNA thio-modification, tRNA wobble uridine modification cytosol, mitochondrion ATP binding, protein binding, tRNA binding, transferase activity Human UniProtKB:P53088 CTU2 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005515=PMID:19017811, GO:0002098=PMID:19017811, GO:0043234=PMID:19017811, GO:0005737=GO_REF:0000052, GO:0034227=PMID:19017811, GO:0008033=GO_REF:0000038} Q2VPK5 Cytoplasmic tRNA 2-thiolation protein 2 protein 20111111 {GO:0005739=IDA, GO:0005515=IPI, GO:0002098=NAS, GO:0043234=IDA, GO:0005737=IDA, GO:0034227=NAS, GO:0008033=IEA} tRNA processing, tRNA thio-modification, tRNA wobble uridine modification cytoplasm, mitochondrion, protein complex protein binding Human CTXN1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} P60606 Cortexin-1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 CUBN Reactome UniProtKB {GO:0006629=Reactome:REACT_602, GO:0005215=PMID:9478979, GO:0015889=PMID:10080186, GO:0005886=Reactome:REACT_13688, GO:0005783=GO_REF:0000019, GO:0030139=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0031526=PMID:11994745, GO:0005765=GO_REF:0000039, GO:0042803=PMID:10552972, GO:0005829=Reactome:REACT_13608, GO:0042953=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0001894=PMID:11994745, GO:0004872=PMID:10080186, GO:0008202=Reactome:REACT_11057, GO:0043202=Reactome:REACT_13664, GO:0008203=GO_REF:0000037, GO:0005794=GO_REF:0000019, GO:0031419=GO_REF:0000037, GO:0042359=Reactome:REACT_13523, GO:0005509=GO_REF:0000002, GO:0031232=PMID:11994745, GO:0006898=PMID:11994745, GO:0005905=GO_REF:0000019, GO:0016020=PMID:9478979, GO:0042157=Reactome:REACT_13621, GO:0010008=GO_REF:0000039} O60494 Cubilin protein 20080410 {GO:0006629=TAS, GO:0005215=TAS, GO:0015889=TAS, GO:0005886=TAS, GO:0005783=IEA, GO:0030139=IEA, GO:0044281=TAS, GO:0031526=NAS, GO:0005765=IEA, GO:0042803=IDA, GO:0005829=TAS, GO:0042953=IEA, GO:0016324=IEA, GO:0001894=NAS, GO:0004872=TAS, GO:0008202=TAS, GO:0043202=TAS, GO:0008203=IEA, GO:0005794=IEA, GO:0031419=IEA, GO:0042359=TAS, GO:0005509=IEA, GO:0031232=NAS, GO:0006898=NAS, GO:0005905=IEA, GO:0016020=TAS, GO:0042157=TAS, GO:0010008=IEA} cholesterol metabolic process, cobalamin transport, lipid metabolic process, lipoprotein metabolic process, lipoprotein transport, receptor-mediated endocytosis, small molecule metabolic process, steroid metabolic process, tissue homeostasis, vitamin D metabolic process Golgi apparatus, apical plasma membrane, brush border membrane, coated pit, cytosol, endocytic vesicle, endoplasmic reticulum, endosome membrane, extrinsic to external side of plasma membrane, lysosomal lumen, lysosomal membrane, membrane, plasma membrane calcium ion binding, cobalamin binding, protein homodimerization activity, receptor activity, transporter activity Human CUEDC1 null null {} null null null null {} null null null CUEDC2 HPA UniProtKB {GO:0005515=PMID:17347654, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9H467 CUE domain-containing protein 2 protein 20110516 {GO:0005515=IPI, GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA} cytoplasm, nucleolus, nucleus protein binding Human CUL1 IntAct UniProtKB {GO:0005515=PMID:20708156, GO:0031461=PMID:22405651, GO:0006513=GO_REF:0000019, GO:0016567=PMID:15103331, GO:0008285=PMID:8681378, GO:0008283=GO_REF:0000019, GO:0051437=Reactome:REACT_6821, GO:0031146=GO_REF:0000024, GO:0031145=Reactome:REACT_6828, GO:0051439=Reactome:REACT_6837, GO:0097193=PMID:8681378, GO:0005829=Reactome:REACT_118856, GO:0000084=Reactome:REACT_899, GO:0000082=Reactome:REACT_1783, GO:0007219=Reactome:REACT_118859, GO:0019048=GO_REF:0000037, GO:0009887=GO_REF:0000019, GO:0005654=Reactome:REACT_160209, GO:0007050=PMID:8681378, GO:0000278=Reactome:REACT_152, GO:0000080=Reactome:REACT_1590, GO:0031625=GO_REF:0000002, GO:0019005=PMID:23263282} Q13616 Cullin-1 protein 20130415 {GO:0005515=IPI, GO:0031461=IDA, GO:0006513=IEA, GO:0016567=IDA, GO:0008285=TAS, GO:0008283=IEA, GO:0051437=TAS, GO:0031146=ISS, GO:0031145=TAS, GO:0051439=TAS, GO:0097193=TAS, GO:0005829=TAS, GO:0000084=TAS, GO:0000082=TAS, GO:0007219=TAS, GO:0019048=IEA, GO:0009887=IEA, GO:0005654=TAS, GO:0007050=TAS, GO:0000278=TAS, GO:0000080=TAS, GO:0031625=IEA, GO:0019005=IDA} G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, Notch signaling pathway, S phase of mitotic cell cycle, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle arrest, cell proliferation, intrinsic apoptotic signaling pathway, mitotic cell cycle, negative regulation of cell proliferation, organ morphogenesis, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein monoubiquitination, protein ubiquitination, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, virus-host interaction SCF ubiquitin ligase complex, cullin-RING ubiquitin ligase complex, cytosol, nucleoplasm protein binding, ubiquitin protein ligase binding Human UniProtKB:Q00987 CUL2 InterPro UniProtKB {GO:0005515=PMID:22190034, GO:0031461=GO_REF:0000002, GO:0006511=GO_REF:0000002, GO:0016567=GO_REF:0000041, GO:0008285=PMID:8681378, GO:0071456=Reactome:REACT_121311, GO:0061418=Reactome:REACT_120815, GO:0033554=Reactome:REACT_120956, GO:0097193=PMID:8681378, GO:0005829=Reactome:REACT_121002, GO:0000082=PMID:8681378, GO:0019048=GO_REF:0000037, GO:0031462=PMID:17636018, GO:0007050=PMID:8681378, GO:0005654=Reactome:REACT_121374, GO:0031625=GO_REF:0000002} Q5T2B7 Cullin-2 protein 20130413 {GO:0005515=IPI, GO:0031461=IEA, GO:0006511=IEA, GO:0016567=IEA, GO:0008285=TAS, GO:0071456=TAS, GO:0061418=TAS, GO:0033554=TAS, GO:0097193=TAS, GO:0005829=TAS, GO:0000082=TAS, GO:0019048=IEA, GO:0031462=IDA, GO:0007050=TAS, GO:0005654=TAS, GO:0031625=IEA} G1/S transition of mitotic cell cycle, cell cycle arrest, cellular response to hypoxia, cellular response to stress, intrinsic apoptotic signaling pathway, negative regulation of cell proliferation, protein ubiquitination, regulation of transcription from RNA polymerase II promoter in response to hypoxia, ubiquitin-dependent protein catabolic process, virus-host interaction Cul2-RING ubiquitin ligase complex, cullin-RING ubiquitin ligase complex, cytosol, nucleoplasm protein binding, ubiquitin protein ligase binding Human InterPro:IPR001373|InterPro:IPR016157|InterPro:IPR016158|InterPro:IPR019559 CUL3 IntAct UniProtKB {GO:0031208=PMID:19261606, GO:0005515=PMID:22939624, GO:0001831=GO_REF:0000019, GO:0031461=GO_REF:0000002, GO:0006511=GO_REF:0000002, GO:0005827=PMID:19995937, GO:0008284=PMID:9733711, GO:0004842=PMID:19261606, GO:0016567=PMID:19782033, GO:0007369=GO_REF:0000019, GO:0006513=PMID:22358839, GO:0035024=PMID:19782033, GO:0017145=GO_REF:0000024, GO:0043149=PMID:19782033, GO:0005634=GO_REF:0000039, GO:0048208=PMID:22358839, GO:0000910=PMID:19995937, GO:0000082=PMID:8681378, GO:0008054=PMID:10500095, GO:0040016=GO_REF:0000024, GO:0007050=PMID:8681378, GO:0016055=GO_REF:0000019, GO:0031625=GO_REF:0000002, GO:0000209=PMID:19261606, GO:0005794=GO_REF:0000039, GO:0051322=PMID:19995937, GO:0032467=PMID:19261606, GO:0030332=GO_REF:0000019, GO:0097193=PMID:8681378, GO:0006888=PMID:22358839, GO:0016477=PMID:19782033, GO:0007229=GO_REF:0000024, GO:0031463=PMID:19261606, GO:0043161=PMID:19261606, GO:0000090=PMID:17543862} Q13618 Cullin-3 protein 20130415 {GO:0031208=IDA, GO:0005515=IPI, GO:0001831=IEA, GO:0031461=IEA, GO:0006511=IEA, GO:0005827=IDA, GO:0008284=TAS, GO:0004842=IDA, GO:0016567=IDA, GO:0007369=IEA, GO:0006513=IDA, GO:0035024=IMP, GO:0017145=ISS, GO:0043149=IMP, GO:0005634=IEA, GO:0048208=IMP, GO:0000910=IMP, GO:0000082=TAS, GO:0008054=IDA, GO:0040016=ISS, GO:0007050=TAS, GO:0016055=IEA, GO:0031625=IEA, GO:0000209=IDA, GO:0005794=IEA, GO:0051322=IMP, GO:0032467=IMP, GO:0030332=IEA, GO:0097193=TAS, GO:0006888=IDA, GO:0016477=IMP, GO:0007229=ISS, GO:0031463=IDA, GO:0043161=IDA, GO:0000090=IMP} COPII vesicle coating, ER to Golgi vesicle-mediated transport, G1/S transition of mitotic cell cycle, Wnt receptor signaling pathway, anaphase, cell cycle arrest, cell migration, cyclin catabolic process, cytokinesis, embryonic cleavage, gastrulation, integrin-mediated signaling pathway, intrinsic apoptotic signaling pathway, mitotic anaphase, negative regulation of Rho protein signal transduction, positive regulation of cell proliferation, positive regulation of cytokinesis, proteasomal ubiquitin-dependent protein catabolic process, protein monoubiquitination, protein polyubiquitination, protein ubiquitination, stem cell division, stress fiber assembly, trophectodermal cellular morphogenesis, ubiquitin-dependent protein catabolic process Cul3-RING ubiquitin ligase complex, Golgi apparatus, cullin-RING ubiquitin ligase complex, nucleus, polar microtubule POZ domain binding, cyclin binding, protein binding, ubiquitin protein ligase binding, ubiquitin-protein ligase activity Human UniProtKB:P08238 CUL4A PINC UniProtKB {GO:0005515=PMID:12504025, GO:0006511=GO_REF:0000002, GO:0051246=GO_REF:0000019, GO:0016567=GO_REF:0000041, GO:0008285=PMID:8681378, GO:0080008=PMID:18381890, GO:0097193=PMID:8681378, GO:0000082=PMID:8681378, GO:0006281=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0045750=GO_REF:0000019, GO:0007050=PMID:8681378, GO:0031464=PMID:20223979, GO:0031625=GO_REF:0000002} Q13619 Cullin-4A protein 20030904 {GO:0005515=IPI, GO:0006511=IEA, GO:0051246=IEA, GO:0016567=IEA, GO:0008285=TAS, GO:0080008=IDA, GO:0097193=TAS, GO:0000082=TAS, GO:0006281=IEA, GO:0019048=IEA, GO:0045750=IEA, GO:0007050=TAS, GO:0031464=IDA, GO:0031625=IEA} DNA repair, G1/S transition of mitotic cell cycle, cell cycle arrest, intrinsic apoptotic signaling pathway, negative regulation of cell proliferation, positive regulation of S phase of mitotic cell cycle, protein ubiquitination, regulation of protein metabolic process, ubiquitin-dependent protein catabolic process, virus-host interaction Cul4-RING ubiquitin ligase complex, Cul4A-RING ubiquitin ligase complex protein binding, ubiquitin protein ligase binding Human CUL4B HPA UniProtKB {GO:0005515=PMID:16964240, GO:0006511=GO_REF:0000002, GO:0031461=GO_REF:0000002, GO:0045732=GO_REF:0000019, GO:0016567=GO_REF:0000041, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0007049=PMID:8681378, GO:0006281=GO_REF:0000037, GO:0045750=GO_REF:0000019, GO:0031465=PMID:18794347, GO:0031625=GO_REF:0000002} Q13620 Cullin-4B protein 20101115 {GO:0005515=IPI, GO:0006511=IEA, GO:0031461=IEA, GO:0045732=IEA, GO:0016567=IEA, GO:0005886=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0007049=NAS, GO:0006281=IEA, GO:0045750=IEA, GO:0031465=IDA, GO:0031625=IEA} DNA repair, cell cycle, positive regulation of S phase of mitotic cell cycle, positive regulation of protein catabolic process, protein ubiquitination, ubiquitin-dependent protein catabolic process Cul4B-RING ubiquitin ligase complex, cullin-RING ubiquitin ligase complex, nucleolus, nucleus, plasma membrane protein binding, ubiquitin protein ligase binding Human CUL5 GOC UniProtKB {GO:0005515=PMID:22190034, GO:0006511=GO_REF:0000002, GO:0031461=GO_REF:0000002, GO:0005262=PMID:9581826, GO:0008285=PMID:8681378, GO:0016567=GO_REF:0000041, GO:0005886=GO_REF:0000019, GO:0008283=PMID:9037604, GO:0051480=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0006970=GO_REF:0000019, GO:0097193=PMID:9581826, GO:0005829=Reactome:REACT_115557, GO:0000082=PMID:8681378, GO:0019048=GO_REF:0000037, GO:0070588=PMID:9581826, GO:0016032=Reactome:REACT_6185, GO:0007050=PMID:8681378, GO:0004872=PMID:9581826, GO:0031466=PMID:22405651, GO:0031625=PMID:17636018} Q93034 Cullin-5 protein 20130413 {GO:0005515=IPI, GO:0006511=IEA, GO:0031461=IEA, GO:0005262=TAS, GO:0008285=TAS, GO:0016567=IEA, GO:0005886=IEA, GO:0008283=TAS, GO:0051480=IEA, GO:0005634=IEA, GO:0006970=IEA, GO:0097193=TAS, GO:0005829=TAS, GO:0000082=TAS, GO:0019048=IEA, GO:0070588=TAS, GO:0016032=TAS, GO:0007050=TAS, GO:0004872=TAS, GO:0031466=IDA, GO:0031625=IDA} G1/S transition of mitotic cell cycle, calcium ion transmembrane transport, cell cycle arrest, cell proliferation, cytosolic calcium ion homeostasis, intrinsic apoptotic signaling pathway, negative regulation of cell proliferation, protein ubiquitination, response to osmotic stress, ubiquitin-dependent protein catabolic process, viral reproduction, virus-host interaction Cul5-RING ubiquitin ligase complex, cullin-RING ubiquitin ligase complex, cytosol, nucleus, plasma membrane calcium channel activity, protein binding, receptor activity, ubiquitin protein ligase binding Human CUL7 HPA UniProtKB {GO:0005515=PMID:17298945, GO:0006511=GO_REF:0000002, GO:0048471=GO_REF:0000039, GO:0005794=GO_REF:0000039, GO:0016567=GO_REF:0000041, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005829=Reactome:REACT_115788, GO:0030968=Reactome:REACT_18356, GO:0005737=GO_REF:0000052, GO:0005680=PMID:12481031, GO:0019048=GO_REF:0000037, GO:0006508=PMID:12481031, GO:0006987=Reactome:REACT_18368, GO:0001570=GO_REF:0000024, GO:0044267=Reactome:REACT_17015, GO:0031625=GO_REF:0000002} Q14999 Cullin-7 protein 20111111 {GO:0005515=IPI, GO:0006511=IEA, GO:0048471=IEA, GO:0005794=IEA, GO:0016567=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005829=TAS, GO:0030968=TAS, GO:0005737=IDA, GO:0005680=NAS, GO:0019048=IEA, GO:0006508=NAS, GO:0006987=TAS, GO:0001570=ISS, GO:0044267=TAS, GO:0031625=IEA} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, protein ubiquitination, proteolysis, ubiquitin-dependent protein catabolic process, vasculogenesis, virus-host interaction Golgi apparatus, anaphase-promoting complex, cytoplasm, cytosol, nucleolus, nucleus, perinuclear region of cytoplasm protein binding, ubiquitin protein ligase binding Human CUL9 IntAct UniProtKB {GO:0005515=PMID:18230339, GO:0031461=GO_REF:0000002, GO:0006511=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0031625=GO_REF:0000002} Q8IWT3 Cullin-9 protein 20130415 {GO:0005515=IPI, GO:0031461=IEA, GO:0006511=IEA, GO:0005737=IEA, GO:0008270=IEA, GO:0005524=IEA, GO:0031625=IEA} ubiquitin-dependent protein catabolic process cullin-RING ubiquitin ligase complex, cytoplasm ATP binding, protein binding, ubiquitin protein ligase binding, zinc ion binding Human UniProtKB:P04637 CUTA IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0008104=PMID:10800960, GO:0016020=PMID:10800960, GO:0010038=GO_REF:0000002, GO:0019899=PMID:10800960} O60888 Protein CutA protein 20130415 {GO:0005515=IPI, GO:0008104=IDA, GO:0016020=IDA, GO:0010038=IEA, GO:0019899=IPI} protein localization, response to metal ion membrane enzyme binding, protein binding Human UniProtKB:P22736 CUTC HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0051262=PMID:19878721, GO:0055070=PMID:16182249, GO:0016235=GO_REF:0000052, GO:0005507=PMID:19878721, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006825=PMID:16182249} Q9NTM9 Copper homeostasis protein cutC homolog protein 20110516 {GO:0005737=IDA, GO:0051262=IPI, GO:0055070=NAS, GO:0016235=IDA, GO:0005507=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0006825=NAS} copper ion homeostasis, copper ion transport, protein tetramerization aggresome, cytoplasm, nucleolus, nucleus copper ion binding Human CUX1 InterPro UniProtKB {GO:0003700=GO_REF:0000002, GO:0042491=GO_REF:0000019, GO:0006357=PMID:1301999, GO:0030324=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0006891=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0007275=PMID:1301999, GO:0000122=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0005829=Reactome:REACT_121382, GO:0043565=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0030173=GO_REF:0000002, GO:0000139=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0000301=GO_REF:0000019, GO:0030674=GO_REF:0000019} Q13948 Protein CASP protein 20130413 {GO:0003700=IEA, GO:0042491=IEA, GO:0006357=TAS, GO:0030324=IEA, GO:0005730=IDA, GO:0006891=IEA, GO:0005634=IDA, GO:0007275=TAS, GO:0000122=IEA, GO:0006351=IEA, GO:0005829=TAS, GO:0043565=IEA, GO:0005737=IDA, GO:0030173=IEA, GO:0000139=IEA, GO:0003682=IEA, GO:0000301=IEA, GO:0030674=IEA} auditory receptor cell differentiation, intra-Golgi vesicle-mediated transport, lung development, multicellular organismal development, negative regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, retrograde transport, vesicle recycling within Golgi, transcription, DNA-dependent Golgi membrane, cytoplasm, cytosol, integral to Golgi membrane, nucleolus, nucleus chromatin binding, protein binding, bridging, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human InterPro:IPR012955 CUX2 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000029, GO:0071310=GO_REF:0000019, GO:0005634=GO_REF:0000029, GO:0045892=GO_REF:0000019, GO:0006351=GO_REF:0000037} O14529 Homeobox protein cut-like 2 protein 20021104 {GO:0043565=IEA, GO:0006355=NAS, GO:0003700=NAS, GO:0071310=IEA, GO:0005634=NAS, GO:0045892=IEA, GO:0006351=IEA} cellular response to organic substance, negative regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human CUZD1 UniProtKB UniProtKB {GO:0006931=PMID:15184879, GO:0007049=GO_REF:0000037, GO:0042589=GO_REF:0000024, GO:0008283=PMID:15184879, GO:0016021=PMID:15184879, GO:0032023=GO_REF:0000024, GO:0030658=GO_REF:0000039, GO:0051301=GO_REF:0000037} Q86UP6 CUB and zona pellucida-like domain-containing protein 1 protein 20060403 {GO:0006931=NAS, GO:0007049=IEA, GO:0042589=ISS, GO:0008283=NAS, GO:0016021=NAS, GO:0032023=ISS, GO:0030658=IEA, GO:0051301=IEA} cell cycle, cell division, cell proliferation, substrate-dependent cell migration, cell attachment to substrate, trypsinogen activation integral to membrane, transport vesicle membrane, zymogen granule membrane Human CWC15 UniProtKB UniProtKB {GO:0005515=PMID:20176811, GO:0000398=PMID:11991638, GO:0003723=GO_REF:0000024, GO:0005681=PMID:20176811, GO:0005634=PMID:20176811, GO:0071013=PMID:11991638} Q9P013 Spliceosome-associated protein CWC15 homolog protein 20120716 {GO:0005515=IPI, GO:0000398=IC, GO:0003723=ISS, GO:0005681=IDA, GO:0005634=IDA, GO:0071013=IDA} mRNA splicing, via spliceosome catalytic step 2 spliceosome, nucleus, spliceosomal complex RNA binding, protein binding Human CWC22 HPA UniProtKB {GO:0048024=PMID:11991638, GO:0005737=GO_REF:0000052, GO:0016070=GO_REF:0000002, GO:0000398=PMID:11991638, GO:0003723=PMID:11991638, GO:0005730=GO_REF:0000052, GO:0005681=PMID:11991638, GO:0005634=GO_REF:0000052, GO:0071013=PMID:11991638, GO:0003677=GO_REF:0000002} Q9HCG8 Pre-mRNA-splicing factor CWC22 homolog protein 20110516 {GO:0048024=IC, GO:0005737=IDA, GO:0016070=IEA, GO:0000398=IC, GO:0003723=IDA, GO:0005730=IDA, GO:0005681=IDA, GO:0005634=IDA, GO:0071013=IDA, GO:0003677=IEA} RNA metabolic process, mRNA splicing, via spliceosome, regulation of mRNA splicing, via spliceosome catalytic step 2 spliceosome, cytoplasm, nucleolus, nucleus, spliceosomal complex DNA binding, RNA binding Human CWC25 null null {} null null null null {} null null null CWC27 UniProtKB UniProtKB {GO:0000398=PMID:11991638, GO:0006457=GO_REF:0000037, GO:0003755=GO_REF:0000003, GO:0071013=PMID:11991638} Q6UX04 Peptidyl-prolyl cis-trans isomerase CWC27 homolog protein 20110302 {GO:0000398=IC, GO:0006457=IEA, GO:0003755=IEA, GO:0071013=IDA} mRNA splicing, via spliceosome, protein folding catalytic step 2 spliceosome peptidyl-prolyl cis-trans isomerase activity Human CWF19L1 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0003824=GO_REF:0000002} Q69YN2 CWF19-like protein 1 protein 20080829 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND, GO:0003824=IEA} biological_process cellular_component catalytic activity, molecular_function Human CWF19L2 InterPro UniProtKB {GO:0003824=GO_REF:0000002} Q2TBE0 CWF19-like protein 2 protein 20130413 {GO:0003824=IEA} catalytic activity Human InterPro:IPR011146 CX3CL1 Reactome UniProtKB {GO:0005515=PMID:9931005, GO:0005886=Reactome:REACT_14810, GO:0019221=PMID:11777952, GO:0005615=GO_REF:0000037, GO:0050902=PMID:12714508, GO:0032914=GO_REF:0000019, GO:0051041=PMID:12714508, GO:0006955=PMID:12714508, GO:0006935=PMID:21829356, GO:0007155=GO_REF:0000037, GO:0008009=PMID:21829356, GO:0043066=GO_REF:0000019, GO:0009986=PMID:12714508, GO:0030595=PMID:11777952, GO:0060055=GO_REF:0000019, GO:0030593=GO_REF:0000019, GO:0005102=PMID:12714508, GO:0005576=PMID:12714508, GO:0006952=PMID:12714508, GO:0045766=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0050729=PMID:11777952, GO:0048247=GO_REF:0000019, GO:0048246=GO_REF:0000019, GO:0016021=PMID:12714508} P78423 Fractalkine protein 20100217 {GO:0005515=IPI, GO:0005886=TAS, GO:0019221=TAS, GO:0005615=IEA, GO:0050902=TAS, GO:0032914=IEA, GO:0051041=IDA, GO:0006955=TAS, GO:0006935=IDA, GO:0007155=IEA, GO:0008009=IDA, GO:0043066=IEA, GO:0009986=IDA, GO:0030595=TAS, GO:0060055=IEA, GO:0030593=IEA, GO:0005102=TAS, GO:0005576=IDA, GO:0006952=TAS, GO:0045766=IEA, GO:0016020=IEA, GO:0050729=IEP, GO:0048247=IEA, GO:0048246=IEA, GO:0016021=IDA} angiogenesis involved in wound healing, cell adhesion, chemotaxis, cytokine-mediated signaling pathway, defense response, immune response, leukocyte adhesive activation, leukocyte chemotaxis, lymphocyte chemotaxis, macrophage chemotaxis, negative regulation of apoptotic process, neutrophil chemotaxis, positive regulation of angiogenesis, positive regulation of calcium-independent cell-cell adhesion, positive regulation of inflammatory response, positive regulation of transforming growth factor beta1 production cell surface, extracellular region, extracellular space, integral to membrane, membrane, plasma membrane chemokine activity, protein binding, receptor binding Human CX3CR1 GOC UniProtKB {GO:0005515=PMID:9931005, GO:0043005=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0005886=Reactome:REACT_14810, GO:0071560=GO_REF:0000019, GO:0007204=GO_REF:0000002, GO:0021795=GO_REF:0000019, GO:0006935=GO_REF:0000002, GO:0004950=PMID:10754298, GO:0002282=GO_REF:0000019, GO:0007155=GO_REF:0000002, GO:0043066=GO_REF:0000019, GO:0030336=GO_REF:0000019, GO:0070098=PMID:10754298, GO:0009611=PMID:10754298, GO:0045766=GO_REF:0000019, GO:0032809=GO_REF:0000019, GO:0006968=PMID:10754298, GO:0071222=GO_REF:0000019, GO:0016495=GO_REF:0000002, GO:0007186=PMID:10754298, GO:0005887=PMID:9390561, GO:0019048=GO_REF:0000037, GO:0016525=GO_REF:0000019, GO:0048246=GO_REF:0000019, GO:0016021=GO_REF:0000038} P49238 CX3C chemokine receptor 1 protein 20130413 {GO:0005515=IPI, GO:0043005=IEA, GO:0048471=IEA, GO:0005886=TAS, GO:0071560=IEA, GO:0007204=IEA, GO:0021795=IEA, GO:0006935=IEA, GO:0004950=TAS, GO:0002282=IEA, GO:0007155=IEA, GO:0043066=IEA, GO:0030336=IEA, GO:0070098=TAS, GO:0009611=TAS, GO:0045766=IEA, GO:0032809=IEA, GO:0006968=TAS, GO:0071222=IEA, GO:0016495=IEA, GO:0007186=TAS, GO:0005887=TAS, GO:0019048=IEA, GO:0016525=IEA, GO:0048246=IEA, GO:0016021=IEA} G-protein coupled receptor signaling pathway, cell adhesion, cellular defense response, cellular response to lipopolysaccharide, cellular response to transforming growth factor beta stimulus, cerebral cortex cell migration, chemokine-mediated signaling pathway, chemotaxis, elevation of cytosolic calcium ion concentration, macrophage chemotaxis, microglial cell activation involved in immune response, negative regulation of angiogenesis, negative regulation of apoptotic process, negative regulation of cell migration, positive regulation of angiogenesis, response to wounding, virus-host interaction integral to membrane, integral to plasma membrane, neuron projection, neuronal cell body membrane, perinuclear region of cytoplasm, plasma membrane C-X3-C chemokine receptor activity, chemokine receptor activity, protein binding Human CXADR HPA UniProtKB {GO:0005515=PMID:11734628, GO:0060044=GO_REF:0000019, GO:0043005=GO_REF:0000024, GO:0030054=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0008013=PMID:12297051, GO:0005634=GO_REF:0000052, GO:0030175=GO_REF:0000024, GO:0050900=Reactome:REACT_12051, GO:0030426=GO_REF:0000024, GO:0086067=GO_REF:0000024, GO:0007507=GO_REF:0000024, GO:0016323=PMID:20361046, GO:0010669=PMID:15304526, GO:0005912=PMID:12297051, GO:0014704=GO_REF:0000019, GO:0005911=PMID:20235596, GO:0050839=PMID:15800062, GO:0071253=GO_REF:0000024, GO:0070633=PMID:15800062, GO:0007157=PMID:15800062, GO:0008354=GO_REF:0000024, GO:0031532=PMID:17675666, GO:0001669=GO_REF:0000024, GO:0030593=PMID:15800062, GO:0005730=GO_REF:0000052, GO:0005576=GO_REF:0000039, GO:0030165=PMID:15364909, GO:0045216=GO_REF:0000024, GO:0044297=GO_REF:0000024, GO:0016327=PMID:15364909, GO:0048739=GO_REF:0000024, GO:0043234=PMID:17675666, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:9096397, GO:0019048=GO_REF:0000037, GO:0050776=Reactome:REACT_11152, GO:0045121=PMID:17675666, GO:0007005=GO_REF:0000024, GO:0005923=PMID:15800062} P78310 Coxsackievirus and adenovirus receptor protein 20120912 {GO:0005515=IPI, GO:0060044=IEA, GO:0043005=ISS, GO:0030054=IDA, GO:0005886=IDA, GO:0008013=IPI, GO:0005634=IDA, GO:0030175=ISS, GO:0050900=TAS, GO:0030426=ISS, GO:0086067=ISS, GO:0007507=ISS, GO:0016323=IDA, GO:0010669=IMP, GO:0005912=IDA, GO:0014704=IEA, GO:0005911=IDA, GO:0050839=IPI, GO:0071253=ISS, GO:0070633=IMP, GO:0007157=IDA, GO:0008354=ISS, GO:0031532=IDA, GO:0001669=ISS, GO:0030593=IMP, GO:0005730=IDA, GO:0005576=IEA, GO:0030165=IPI, GO:0045216=ISS, GO:0044297=ISS, GO:0016327=IDA, GO:0048739=ISS, GO:0043234=IDA, GO:0007596=TAS, GO:0005887=NAS, GO:0019048=IEA, GO:0050776=TAS, GO:0045121=IDA, GO:0007005=ISS, GO:0005923=IDA} AV node cell to bundle of His cell communication, actin cytoskeleton reorganization, blood coagulation, cardiac muscle fiber development, cell-cell junction organization, epithelial structure maintenance, germ cell migration, heart development, heterophilic cell-cell adhesion, leukocyte migration, mitochondrion organization, negative regulation of cardiac muscle cell proliferation, neutrophil chemotaxis, regulation of immune response, transepithelial transport, virus-host interaction acrosomal vesicle, adherens junction, apicolateral plasma membrane, basolateral plasma membrane, cell body, cell junction, cell-cell junction, extracellular region, filopodium, growth cone, integral to plasma membrane, intercalated disc, membrane raft, neuron projection, nucleolus, nucleus, plasma membrane, protein complex, tight junction PDZ domain binding, beta-catenin binding, cell adhesion molecule binding, connexin binding, protein binding Human CXCL1 GOC UniProtKB {GO:0008009=GO_REF:0000002, GO:0008285=PMID:9551928, GO:0030036=PMID:9725262, GO:0008283=PMID:8380167, GO:0005102=PMID:9079638, GO:0005576=Reactome:REACT_22289, GO:0043085=PMID:9079638, GO:0005615=GO_REF:0000037, GO:0007399=PMID:9058825, GO:0035556=PMID:9551928, GO:0007165=PMID:9725262, GO:0006955=GO_REF:0000002, GO:0006954=GO_REF:0000037, GO:0006935=PMID:10820279, GO:0007186=PMID:10820279, GO:0008047=PMID:9079638, GO:0008083=GO_REF:0000037} P09341 Growth-regulated alpha protein protein 20130413 {GO:0008009=IEA, GO:0008285=TAS, GO:0030036=TAS, GO:0008283=TAS, GO:0005102=TAS, GO:0005576=TAS, GO:0043085=TAS, GO:0005615=IEA, GO:0007399=TAS, GO:0035556=TAS, GO:0007165=TAS, GO:0006955=IEA, GO:0006954=IEA, GO:0006935=TAS, GO:0007186=TAS, GO:0008047=TAS, GO:0008083=IEA} G-protein coupled receptor signaling pathway, actin cytoskeleton organization, cell proliferation, chemotaxis, immune response, inflammatory response, intracellular signal transduction, negative regulation of cell proliferation, nervous system development, positive regulation of catalytic activity, signal transduction extracellular region, extracellular space chemokine activity, enzyme activator activity, growth factor activity, receptor binding Human CXCL10 BHF-UCL UniProtKB {GO:0008284=GO_REF:0000002, GO:0009306=GO_REF:0000019, GO:0008603=PMID:10903763, GO:0010996=GO_REF:0000019, GO:0008015=PMID:8798675, GO:0009409=GO_REF:0000019, GO:0007267=PMID:3925348, GO:0033280=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0034605=GO_REF:0000019, GO:0006955=GO_REF:0000019, GO:0051607=GO_REF:0000019, GO:0006954=GO_REF:0000037, GO:0006935=GO_REF:0000037, GO:0032496=GO_REF:0000019, GO:0010332=GO_REF:0000019, GO:0008009=GO_REF:0000002, GO:0005102=PMID:10201891, GO:0005576=PMID:20041150, GO:0002690=GO_REF:0000019, GO:0007165=PMID:10201891, GO:0007517=PMID:8798675, GO:0016525=GO_REF:0000019, GO:0009897=GO_REF:0000019, GO:0007166=PMID:10903763} P02778 C-X-C motif chemokine 10 protein 20120622 {GO:0008284=IEA, GO:0009306=IEA, GO:0008603=TAS, GO:0010996=IEA, GO:0008015=TAS, GO:0009409=IEA, GO:0007267=TAS, GO:0033280=IEA, GO:0005615=IEA, GO:0034605=IEA, GO:0006955=IEA, GO:0051607=IEA, GO:0006954=IEA, GO:0006935=IEA, GO:0032496=IEA, GO:0010332=IEA, GO:0008009=IEA, GO:0005102=TAS, GO:0005576=IDA, GO:0002690=IEA, GO:0007165=TAS, GO:0007517=TAS, GO:0016525=IEA, GO:0009897=IEA, GO:0007166=TAS} blood circulation, cell surface receptor signaling pathway, cell-cell signaling, cellular response to heat, chemotaxis, defense response to virus, immune response, inflammatory response, muscle organ development, negative regulation of angiogenesis, positive regulation of cell proliferation, positive regulation of leukocyte chemotaxis, protein secretion, response to auditory stimulus, response to cold, response to gamma radiation, response to lipopolysaccharide, response to vitamin D, signal transduction external side of plasma membrane, extracellular region, extracellular space cAMP-dependent protein kinase regulator activity, chemokine activity, receptor binding Human CXCL11 Reactome UniProtKB {GO:0007165=PMID:10233762, GO:0008009=GO_REF:0000019, GO:0006955=GO_REF:0000019, GO:0006954=GO_REF:0000037, GO:0006935=GO_REF:0000037, GO:0007267=PMID:10233762, GO:0005576=Reactome:REACT_22289, GO:0005615=GO_REF:0000037} O14625 C-X-C motif chemokine 11 protein 20080717 {GO:0007165=TAS, GO:0008009=IEA, GO:0006955=IEA, GO:0006954=IEA, GO:0006935=IEA, GO:0007267=TAS, GO:0005576=TAS, GO:0005615=IEA} cell-cell signaling, chemotaxis, immune response, inflammatory response, signal transduction extracellular region, extracellular space chemokine activity Human CXCL12 BHF-UCL UniProtKB {GO:0008015=PMID:10772939, GO:0007281=GO_REF:0000019, GO:0005615=GO_REF:0000037, GO:0006955=GO_REF:0000002, GO:0042098=GO_REF:0000019, GO:0006935=PMID:10620615, GO:0007155=PMID:10198043, GO:0008009=GO_REF:0000019, GO:0043066=PMID:20388803, GO:0008354=GO_REF:0000019, GO:0001569=GO_REF:0000019, GO:0070098=PMID:20388803, GO:0001667=GO_REF:0000019, GO:0005102=PMID:10438529, GO:0006874=PMID:10772939, GO:0005576=Reactome:REACT_115653, GO:0045236=PMID:20388803, GO:0009615=PMID:10772939, GO:0050930=GO_REF:0000019, GO:0007165=PMID:10491003, GO:0008045=GO_REF:0000019, GO:0007186=PMID:8752280, GO:0007420=GO_REF:0000019, GO:0008064=PMID:10570282, GO:2000107=PMID:15059845, GO:0090026=PMID:18802065, GO:0008083=GO_REF:0000037, GO:0009897=GO_REF:0000019} P48061 Stromal cell-derived factor 1 protein 20110708 {GO:0008015=TAS, GO:0007281=IEA, GO:0005615=IEA, GO:0006955=IEA, GO:0042098=IEA, GO:0006935=TAS, GO:0007155=TAS, GO:0008009=IEA, GO:0043066=IDA, GO:0008354=IEA, GO:0001569=IEA, GO:0070098=IDA, GO:0001667=IEA, GO:0005102=TAS, GO:0006874=TAS, GO:0005576=TAS, GO:0045236=IDA, GO:0009615=TAS, GO:0050930=IEA, GO:0007165=TAS, GO:0008045=IEA, GO:0007186=TAS, GO:0007420=IEA, GO:0008064=TAS, GO:2000107=IDA, GO:0090026=IDA, GO:0008083=IEA, GO:0009897=IEA} G-protein coupled receptor signaling pathway, T cell proliferation, ameboidal cell migration, blood circulation, brain development, cell adhesion, cellular calcium ion homeostasis, chemokine-mediated signaling pathway, chemotaxis, germ cell development, germ cell migration, immune response, induction of positive chemotaxis, motor neuron axon guidance, negative regulation of apoptotic process, negative regulation of leukocyte apoptotic process, patterning of blood vessels, positive regulation of monocyte chemotaxis, regulation of actin polymerization or depolymerization, response to virus, signal transduction external side of plasma membrane, extracellular region, extracellular space CXCR chemokine receptor binding, chemokine activity, growth factor activity, receptor binding Human CXCL13 GOC UniProtKB {GO:0035769=GO_REF:0000019, GO:0035768=PMID:11708770, GO:0048248=PMID:11554781, GO:0007267=PMID:11554781, GO:0033625=GO_REF:0000024, GO:0007204=PMID:11554781, GO:0005615=GO_REF:0000037, GO:0002518=GO_REF:0000024, GO:0048535=GO_REF:0000019, GO:0031724=PMID:9463416, GO:0006955=PMID:11554781, GO:0002920=PMID:16531331, GO:0002467=PMID:16543475, GO:0008201=PMID:11708770, GO:0048018=PMID:11554781, GO:0042742=PMID:17562761, GO:0008009=PMID:11554781, GO:0043066=PMID:15580304, GO:0046982=PMID:11708770, GO:0017134=PMID:11708770, GO:0010820=PMID:11554781, GO:0045765=PMID:11708770, GO:2000545=PMID:11708770, GO:0032861=GO_REF:0000024, GO:0005576=PMID:17562761, GO:0002544=PMID:15284119, GO:0033634=GO_REF:0000024, GO:0031735=PMID:10706668, GO:0007165=PMID:11554781, GO:0035754=PMID:9463416} O43927 C-X-C motif chemokine 13 protein 20130413 {GO:0035769=IEA, GO:0035768=IDA, GO:0048248=IPI, GO:0007267=IDA, GO:0033625=ISS, GO:0007204=IDA, GO:0005615=IEA, GO:0002518=ISS, GO:0048535=IEA, GO:0031724=IDA, GO:0006955=IC, GO:0002920=NAS, GO:0002467=NAS, GO:0008201=IDA, GO:0048018=IDA, GO:0042742=IDA, GO:0008009=IDA, GO:0043066=NAS, GO:0046982=IDA, GO:0017134=IDA, GO:0010820=IDA, GO:0045765=NAS, GO:2000545=IDA, GO:0032861=ISS, GO:0005576=IDA, GO:0002544=NAS, GO:0033634=ISS, GO:0031735=IDA, GO:0007165=IDA, GO:0035754=IDA} B cell chemotaxis, B cell chemotaxis across high endothelial venule, activation of Rap GTPase activity, cell-cell signaling, chronic inflammatory response, defense response to bacterium, elevation of cytosolic calcium ion concentration, endothelial cell chemotaxis to fibroblast growth factor, germinal center formation, immune response, lymph node development, lymphocyte chemotaxis across high endothelial venule, negative regulation of apoptotic process, negative regulation of endothelial cell chemotaxis to fibroblast growth factor, positive regulation of T cell chemotaxis, positive regulation of cell-cell adhesion mediated by integrin, positive regulation of integrin activation, regulation of angiogenesis, regulation of humoral immune response, signal transduction extracellular region, extracellular space CCR10 chemokine receptor binding, CXCR3 chemokine receptor binding, CXCR5 chemokine receptor binding, chemokine activity, fibroblast growth factor binding, heparin binding, protein heterodimerization activity, receptor agonist activity Human CXCL14 LIFEdb UniProtKB {GO:0007165=PMID:10049774, GO:0008009=GO_REF:0000002, GO:0048839=GO_REF:0000019, GO:0006955=GO_REF:0000002, GO:0005794=GO_REF:0000054, GO:0006935=GO_REF:0000037, GO:0007267=PMID:10049774, GO:0005615=GO_REF:0000037} O95715 C-X-C motif chemokine 14 protein 20100607 {GO:0007165=TAS, GO:0008009=IEA, GO:0048839=IEA, GO:0006955=IEA, GO:0005794=IDA, GO:0006935=IEA, GO:0007267=TAS, GO:0005615=IEA} cell-cell signaling, chemotaxis, immune response, inner ear development, signal transduction Golgi apparatus, extracellular space chemokine activity Human CXCL16 BHF-UCL UniProtKB {GO:0008009=PMID:18373975, GO:0030335=PMID:18373975, GO:0005886=GO_REF:0000039, GO:0030307=PMID:18373975, GO:0005102=PMID:11017100, GO:0005576=Reactome:REACT_22289, GO:0005615=PMID:18373975, GO:0006898=PMID:11060282, GO:0005041=GO_REF:0000024, GO:0016020=PMID:11060282, GO:0006935=PMID:11290797, GO:0034612=PMID:18373975, GO:0048247=PMID:11017100, GO:0034341=PMID:18373975, GO:0016021=PMID:11017100, GO:0034097=PMID:18373975, GO:0005044=PMID:11060282} Q9H2A7 C-X-C motif chemokine 16 protein 20081119 {GO:0008009=IDA, GO:0030335=IMP, GO:0005886=IEA, GO:0030307=IMP, GO:0005102=NAS, GO:0005576=TAS, GO:0005615=IDA, GO:0006898=NAS, GO:0005041=ISS, GO:0016020=TAS, GO:0006935=NAS, GO:0034612=IDA, GO:0048247=NAS, GO:0034341=IDA, GO:0016021=NAS, GO:0034097=IDA, GO:0005044=TAS} chemotaxis, lymphocyte chemotaxis, positive regulation of cell growth, positive regulation of cell migration, receptor-mediated endocytosis, response to cytokine stimulus, response to interferon-gamma, response to tumor necrosis factor extracellular region, extracellular space, integral to membrane, membrane, plasma membrane chemokine activity, low-density lipoprotein receptor activity, receptor binding, scavenger receptor activity Human CXCL2 BHF-UCL UniProtKB {GO:0008009=GO_REF:0000002, GO:0006955=GO_REF:0000002, GO:0006954=GO_REF:0000037, GO:0006935=GO_REF:0000037, GO:0002237=PMID:19912257, GO:0005576=Reactome:REACT_22289, GO:0005615=GO_REF:0000037} P19875 C-X-C motif chemokine 2 protein 20110202 {GO:0008009=IEA, GO:0006955=IEA, GO:0006954=IEA, GO:0006935=IEA, GO:0002237=IDA, GO:0005576=TAS, GO:0005615=IEA} chemotaxis, immune response, inflammatory response, response to molecule of bacterial origin extracellular region, extracellular space chemokine activity Human CXCL3 Reactome UniProtKB {GO:0008009=GO_REF:0000024, GO:0006955=GO_REF:0000002, GO:0006954=GO_REF:0000037, GO:0030593=GO_REF:0000024, GO:0005576=Reactome:REACT_22289, GO:0005615=PMID:10095777} P19876 C-X-C motif chemokine 3 protein 20080717 {GO:0008009=ISS, GO:0006955=IEA, GO:0006954=IEA, GO:0030593=ISS, GO:0005576=TAS, GO:0005615=IDA} immune response, inflammatory response, neutrophil chemotaxis extracellular region, extracellular space chemokine activity Human CXCL5 Reactome UniProtKB {GO:0007165=PMID:10820279, GO:0008009=GO_REF:0000002, GO:0008284=PMID:10463948, GO:0006955=GO_REF:0000002, GO:0006935=PMID:10820279, GO:0007267=PMID:7929219, GO:0005576=Reactome:REACT_22289, GO:0005615=GO_REF:0000037} P42830 C-X-C motif chemokine 5 protein 20080717 {GO:0007165=TAS, GO:0008009=IEA, GO:0008284=TAS, GO:0006955=IEA, GO:0006935=TAS, GO:0007267=TAS, GO:0005576=TAS, GO:0005615=IEA} cell-cell signaling, chemotaxis, immune response, positive regulation of cell proliferation, signal transduction extracellular region, extracellular space chemokine activity Human CXCL6 Reactome UniProtKB {GO:0007165=PMID:9164944, GO:0008009=GO_REF:0000002, GO:0006955=GO_REF:0000002, GO:0006954=PMID:8399143, GO:0006935=GO_REF:0000037, GO:0007267=PMID:9164944, GO:0005576=Reactome:REACT_22289, GO:0008201=GO_REF:0000037, GO:0005615=GO_REF:0000037} P80162 C-X-C motif chemokine 6 protein 20080717 {GO:0007165=TAS, GO:0008009=IEA, GO:0006955=IEA, GO:0006954=TAS, GO:0006935=IEA, GO:0007267=TAS, GO:0005576=TAS, GO:0008201=IEA, GO:0005615=IEA} cell-cell signaling, chemotaxis, immune response, inflammatory response, signal transduction extracellular region, extracellular space chemokine activity, heparin binding Human CXCL9 Reactome UniProtKB {GO:0008009=GO_REF:0000002, GO:0007267=PMID:8476424, GO:0005576=Reactome:REACT_22289, GO:0006952=PMID:2115167, GO:0005615=GO_REF:0000019, GO:0005125=PMID:2115167, GO:0007165=PMID:10201901, GO:0006955=GO_REF:0000002, GO:0051607=GO_REF:0000019, GO:0006968=PMID:10570316, GO:0006954=GO_REF:0000037, GO:0006935=GO_REF:0000002, GO:0007186=PMID:10903763, GO:0009897=GO_REF:0000019} Q07325 C-X-C motif chemokine 9 protein 20080717 {GO:0008009=IEA, GO:0007267=TAS, GO:0005576=TAS, GO:0006952=TAS, GO:0005615=IEA, GO:0005125=TAS, GO:0007165=TAS, GO:0006955=IEA, GO:0051607=IEA, GO:0006968=TAS, GO:0006954=IEA, GO:0006935=IEA, GO:0007186=TAS, GO:0009897=IEA} G-protein coupled receptor signaling pathway, cell-cell signaling, cellular defense response, chemotaxis, defense response, defense response to virus, immune response, inflammatory response, signal transduction external side of plasma membrane, extracellular region, extracellular space chemokine activity, cytokine activity Human CXCR1 GOC UniProtKB {GO:0031584=GO_REF:0000002, GO:0070098=PMID:1840701, GO:0005886=Reactome:REACT_22289, GO:0004930=PMID:8381837, GO:0030818=GO_REF:0000002, GO:0002407=PMID:16621978, GO:0004918=PMID:10734056, GO:0019959=PMID:11564821, GO:0007204=GO_REF:0000002, GO:0031682=GO_REF:0000002, GO:0006954=PMID:10725748, GO:0006935=PMID:10725748, GO:0007186=PMID:8381837, GO:0016020=PMID:10725748, GO:0004950=PMID:1840701, GO:0038112=PMID:10734056, GO:0016021=GO_REF:0000037, GO:0007166=PMID:10734056} P25024 C-X-C chemokine receptor type 1 protein 20130413 {GO:0031584=IEA, GO:0070098=TAS, GO:0005886=TAS, GO:0004930=TAS, GO:0030818=IEA, GO:0002407=TAS, GO:0004918=IDA, GO:0019959=IPI, GO:0007204=IEA, GO:0031682=IEA, GO:0006954=TAS, GO:0006935=TAS, GO:0007186=TAS, GO:0016020=TAS, GO:0004950=TAS, GO:0038112=IDA, GO:0016021=IEA, GO:0007166=IDA} G-protein coupled receptor signaling pathway, activation of phospholipase D activity, cell surface receptor signaling pathway, chemokine-mediated signaling pathway, chemotaxis, dendritic cell chemotaxis, elevation of cytosolic calcium ion concentration, inflammatory response, interleukin-8-mediated signaling pathway, negative regulation of cAMP biosynthetic process integral to membrane, membrane, plasma membrane G-protein coupled receptor activity, G-protein gamma-subunit binding, chemokine receptor activity, interleukin-8 binding, interleukin-8 receptor activity Human CXCR2 GOC UniProtKB {GO:0008284=PMID:10438939, GO:0005886=Reactome:REACT_22289, GO:0030818=GO_REF:0000002, GO:0007200=PMID:10438939, GO:0019959=PMID:1840701, GO:0007204=GO_REF:0000019, GO:0042629=PMID:9725262, GO:0005622=PMID:10878382, GO:0006954=PMID:9725262, GO:0006935=PMID:10725748, GO:0038112=PMID:10820279, GO:0004871=PMID:10878382, GO:0009986=PMID:10878382, GO:0030593=PMID:10820279, GO:0002407=PMID:16621978, GO:0006915=GO_REF:0000019, GO:0004918=PMID:10820279, GO:0031682=GO_REF:0000002, GO:0007165=PMID:10820279, GO:0006968=PMID:10725748, GO:0016020=PMID:10725748, GO:0016494=PMID:10878382, GO:0005887=PMID:10438939, GO:0016021=GO_REF:0000038, GO:0042119=PMID:10878382, GO:0007166=PMID:10734056} P25025 C-X-C chemokine receptor type 2 protein 20130413 {GO:0008284=IDA, GO:0005886=TAS, GO:0030818=IEA, GO:0007200=IDA, GO:0019959=IPI, GO:0007204=IEA, GO:0042629=IDA, GO:0005622=IDA, GO:0006954=TAS, GO:0006935=IDA, GO:0038112=IDA, GO:0004871=IDA, GO:0009986=IDA, GO:0030593=IDA, GO:0002407=TAS, GO:0006915=IEA, GO:0004918=IDA, GO:0031682=IEA, GO:0007165=IDA, GO:0006968=IDA, GO:0016020=IDA, GO:0016494=IDA, GO:0005887=TAS, GO:0016021=IEA, GO:0042119=IDA, GO:0007166=IDA} apoptotic process, cell surface receptor signaling pathway, cellular defense response, chemotaxis, dendritic cell chemotaxis, elevation of cytosolic calcium ion concentration, inflammatory response, interleukin-8-mediated signaling pathway, negative regulation of cAMP biosynthetic process, neutrophil activation, neutrophil chemotaxis, phospholipase C-activating G-protein coupled receptor signaling pathway, positive regulation of cell proliferation, signal transduction cell surface, integral to membrane, integral to plasma membrane, intracellular, mast cell granule, membrane, plasma membrane C-X-C chemokine receptor activity, G-protein gamma-subunit binding, interleukin-8 binding, interleukin-8 receptor activity, signal transducer activity Human CXCR3 BHF-UCL UniProtKB {GO:0019722=GO_REF:0000019, GO:0005886=Reactome:REACT_22289, GO:0006928=PMID:10741397, GO:0006915=GO_REF:0000037, GO:0002685=GO_REF:0000002, GO:0001525=GO_REF:0000037, GO:0019958=GO_REF:0000002, GO:0007204=GO_REF:0000019, GO:0019957=GO_REF:0000002, GO:0010818=GO_REF:0000019, GO:0019956=PMID:11554781, GO:0033622=GO_REF:0000002, GO:0005737=PMID:10903743, GO:0006954=GO_REF:0000002, GO:0006935=PMID:10903763, GO:0043405=GO_REF:0000002, GO:0005887=PMID:9064356, GO:0043551=GO_REF:0000002, GO:0016494=GO_REF:0000019, GO:0004950=PMID:9064356, GO:0007155=PMID:10942362, GO:0009897=GO_REF:0000019} P49682 C-X-C chemokine receptor type 3 protein 20110329 {GO:0019722=IEA, GO:0005886=TAS, GO:0006928=TAS, GO:0006915=IEA, GO:0002685=IEA, GO:0001525=IEA, GO:0019958=IEA, GO:0007204=IEA, GO:0019957=IEA, GO:0010818=IEA, GO:0019956=IPI, GO:0033622=IEA, GO:0005737=TAS, GO:0006954=IEA, GO:0006935=TAS, GO:0043405=IEA, GO:0005887=TAS, GO:0043551=IEA, GO:0016494=IEA, GO:0004950=TAS, GO:0007155=TAS, GO:0009897=IEA} T cell chemotaxis, angiogenesis, apoptotic process, calcium-mediated signaling, cell adhesion, cellular component movement, chemotaxis, elevation of cytosolic calcium ion concentration, inflammatory response, integrin activation, regulation of MAP kinase activity, regulation of leukocyte migration, regulation of phosphatidylinositol 3-kinase activity cytoplasm, external side of plasma membrane, integral to plasma membrane, plasma membrane C-C chemokine binding, C-X-C chemokine binding, C-X-C chemokine receptor activity, chemokine binding, chemokine receptor activity Human UniProtKB:O43927 CXCR4 BHF-UCL UniProtKB {GO:0005515=PMID:10644702, GO:0022415=Reactome:REACT_6266, GO:0043130=PMID:20228059, GO:0019722=PMID:19064997, GO:0005886=Reactome:REACT_14783, GO:0030260=Reactome:REACT_6903, GO:0007281=GO_REF:0000019, GO:0019958=GO_REF:0000002, GO:0007204=GO_REF:0000002, GO:0030426=GO_REF:0000019, GO:0061351=GO_REF:0000019, GO:0000187=PMID:10570282, GO:0005737=PMID:10415069, GO:0006954=PMID:8276799, GO:0042098=GO_REF:0000019, GO:0050920=PMID:19106094, GO:0016032=Reactome:REACT_6256, GO:0031252=PMID:12421915, GO:0031625=PMID:19116316, GO:0032027=PMID:12421915, GO:0030334=GO_REF:0000019, GO:0001666=PMID:15174142, GO:0008354=GO_REF:0000019, GO:0001569=GO_REF:0000019, GO:0009986=PMID:10521508, GO:0004930=PMID:8276799, GO:0001667=GO_REF:0000019, GO:0002407=PMID:16621978, GO:0006915=PMID:10942389, GO:0003779=PMID:12421915, GO:0031410=PMID:10521508, GO:0009615=PMID:10583963, GO:0015026=PMID:10754293, GO:0008045=GO_REF:0000019, GO:0007186=PMID:10644702, GO:0007420=GO_REF:0000019, GO:0016494=PMID:9468539, GO:0048714=GO_REF:0000024, GO:0019048=GO_REF:0000037, GO:0043217=GO_REF:0000024, GO:0016023=PMID:19106094, GO:0016021=GO_REF:0000037, GO:0042119=GO_REF:0000002, GO:0001764=GO_REF:0000019, GO:0009897=GO_REF:0000019} P61073 C-X-C chemokine receptor type 4 protein 20110713 {GO:0005515=IPI, GO:0022415=TAS, GO:0043130=IDA, GO:0019722=IMP, GO:0005886=TAS, GO:0030260=TAS, GO:0007281=IEA, GO:0019958=IEA, GO:0007204=IEA, GO:0030426=IEA, GO:0061351=IEA, GO:0000187=TAS, GO:0005737=TAS, GO:0006954=TAS, GO:0042098=IEA, GO:0050920=IMP, GO:0016032=TAS, GO:0031252=IDA, GO:0031625=IPI, GO:0032027=IDA, GO:0030334=IEA, GO:0001666=IEP, GO:0008354=IEA, GO:0001569=IEA, GO:0009986=IDA, GO:0004930=TAS, GO:0001667=IEA, GO:0002407=TAS, GO:0006915=TAS, GO:0003779=IDA, GO:0031410=IDA, GO:0009615=TAS, GO:0015026=TAS, GO:0008045=IEA, GO:0007186=IDA, GO:0007420=IEA, GO:0016494=NAS, GO:0048714=ISS, GO:0019048=IEA, GO:0043217=ISS, GO:0016023=IDA, GO:0016021=IEA, GO:0042119=IEA, GO:0001764=IEA, GO:0009897=IEA} G-protein coupled receptor signaling pathway, T cell proliferation, activation of MAPK activity, ameboidal cell migration, apoptotic process, brain development, calcium-mediated signaling, dendritic cell chemotaxis, elevation of cytosolic calcium ion concentration, entry into host cell, germ cell development, germ cell migration, inflammatory response, motor neuron axon guidance, myelin maintenance, neural precursor cell proliferation, neuron migration, neutrophil activation, patterning of blood vessels, positive regulation of oligodendrocyte differentiation, regulation of cell migration, regulation of chemotaxis, response to hypoxia, response to virus, viral reproduction, viral reproductive process, virus-host interaction cell leading edge, cell surface, cytoplasm, cytoplasmic membrane-bounded vesicle, cytoplasmic vesicle, external side of plasma membrane, growth cone, integral to membrane, plasma membrane C-X-C chemokine binding, C-X-C chemokine receptor activity, G-protein coupled receptor activity, actin binding, coreceptor activity, myosin light chain binding, protein binding, ubiquitin binding, ubiquitin protein ligase binding Human UniProtKB:P70658 CXCR5 Reactome UniProtKB {GO:0042113=GO_REF:0000037, GO:0006955=GO_REF:0000002, GO:0005886=Reactome:REACT_22289, GO:0007186=PMID:1425907, GO:0006935=GO_REF:0000002, GO:0005887=PMID:1425907, GO:0004930=PMID:1425907, GO:0016494=GO_REF:0000002, GO:0006928=PMID:1425907, GO:0019958=GO_REF:0000002, GO:0007204=GO_REF:0000002, GO:0048535=GO_REF:0000019} P32302 C-X-C chemokine receptor type 5 protein 20100217 {GO:0042113=IEA, GO:0006955=IEA, GO:0005886=TAS, GO:0007186=TAS, GO:0006935=IEA, GO:0005887=TAS, GO:0004930=TAS, GO:0016494=IEA, GO:0006928=TAS, GO:0019958=IEA, GO:0007204=IEA, GO:0048535=IEA} B cell activation, G-protein coupled receptor signaling pathway, cellular component movement, chemotaxis, elevation of cytosolic calcium ion concentration, immune response, lymph node development integral to plasma membrane, plasma membrane C-X-C chemokine binding, C-X-C chemokine receptor activity, G-protein coupled receptor activity Human CXCR6 Reactome UniProtKB {GO:0016464=GO_REF:0000002, GO:0006954=GO_REF:0000002, GO:0005886=Reactome:REACT_22289, GO:0007186=PMID:9166430, GO:0006935=GO_REF:0000002, GO:0004930=PMID:9166430, GO:0005887=PMID:9166430, GO:0016494=GO_REF:0000019, GO:0015026=GO_REF:0000002, GO:0019079=PMID:9230441, GO:0007204=GO_REF:0000002, GO:0051133=GO_REF:0000002} O00574 C-X-C chemokine receptor type 6 protein 20100217 {GO:0016464=IEA, GO:0006954=IEA, GO:0005886=TAS, GO:0007186=TAS, GO:0006935=IEA, GO:0004930=TAS, GO:0005887=TAS, GO:0016494=IEA, GO:0015026=IEA, GO:0019079=TAS, GO:0007204=IEA, GO:0051133=IEA} G-protein coupled receptor signaling pathway, chemotaxis, elevation of cytosolic calcium ion concentration, inflammatory response, regulation of NK T cell activation, viral genome replication integral to plasma membrane, plasma membrane C-X-C chemokine receptor activity, G-protein coupled receptor activity, chloroplast protein-transporting ATPase activity, coreceptor activity Human CXCR7 BHF-UCL UniProtKB {GO:0043066=PMID:20388803, GO:0048471=GO_REF:0000039, GO:0070098=PMID:20388803, GO:0005886=Reactome:REACT_22289, GO:0001525=GO_REF:0000002, GO:0015026=GO_REF:0000002, GO:0019956=GO_REF:0000002, GO:0006935=GO_REF:0000002, GO:0016494=PMID:20388803, GO:0019048=GO_REF:0000037, GO:0016021=GO_REF:0000029, GO:0007155=GO_REF:0000037, GO:0055037=GO_REF:0000039, GO:0001570=GO_REF:0000002, GO:0005769=GO_REF:0000039} P25106 C-X-C chemokine receptor type 7 protein 20110708 {GO:0043066=IMP, GO:0048471=IEA, GO:0070098=IMP, GO:0005886=TAS, GO:0001525=IEA, GO:0015026=IEA, GO:0019956=IEA, GO:0006935=IEA, GO:0016494=IMP, GO:0019048=IEA, GO:0016021=NAS, GO:0007155=IEA, GO:0055037=IEA, GO:0001570=IEA, GO:0005769=IEA} angiogenesis, cell adhesion, chemokine-mediated signaling pathway, chemotaxis, negative regulation of apoptotic process, vasculogenesis, virus-host interaction early endosome, integral to membrane, perinuclear region of cytoplasm, plasma membrane, recycling endosome C-X-C chemokine receptor activity, chemokine binding, coreceptor activity Human CXorf23 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039} A2AJT9 Uncharacterized protein CXorf23 protein 20130413 {GO:0005739=IEA} mitochondrion Human UniProtKB-SubCell:SL-0173 CXorf27 InterPro UniProtKB {GO:0046982=GO_REF:0000002} O75409 Huntingtin-interacting protein M protein 20130413 {GO:0046982=IEA} protein heterodimerization activity Human InterPro:IPR009072 CXorf38 null null {} null null null null {} null null null CXorf40A IntAct UniProtKB {GO:0005515=PMID:15541360} Q8TE69 Protein CXorf40A protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:P02795 CXorf56 null null {} null null null null {} null null null CXorf57 null null {} null null null null {} null null null CXorf61 null null {} null null null null {} null null null CXorf67 null null {} null null null null {} null null null CXXC1 LIFEdb UniProtKB {GO:0005515=PMID:17998332, GO:0006355=PMID:10688657, GO:0005634=PMID:10688657, GO:0003677=GO_REF:0000002, GO:0042800=PMID:17355966, GO:0006351=GO_REF:0000037, GO:0016363=GO_REF:0000019, GO:0030968=Reactome:REACT_18356, GO:0045322=PMID:10688657, GO:0035097=PMID:17355966, GO:0016607=GO_REF:0000054, GO:0048188=PMID:18838538, GO:0005654=Reactome:REACT_115869, GO:0008270=GO_REF:0000002, GO:0006987=Reactome:REACT_18368, GO:0045893=PMID:10688657, GO:0044267=Reactome:REACT_17015, GO:0051568=PMID:17355966} Q9P0U4 CpG-binding protein protein 20100607 {GO:0005515=IPI, GO:0006355=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0042800=IDA, GO:0006351=IEA, GO:0016363=IEA, GO:0030968=TAS, GO:0045322=IDA, GO:0035097=IDA, GO:0016607=IDA, GO:0048188=IDA, GO:0005654=TAS, GO:0008270=IEA, GO:0006987=TAS, GO:0045893=IDA, GO:0044267=TAS, GO:0051568=IDA} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, histone H3-K4 methylation, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent Set1C/COMPASS complex, histone methyltransferase complex, nuclear matrix, nuclear speck, nucleoplasm, nucleus DNA binding, histone methyltransferase activity (H3-K4 specific), protein binding, unmethylated CpG binding, zinc ion binding Human CXXC4 BHF-UCL UniProtKB {GO:0005737=PMID:11113207, GO:0030178=PMID:11113207, GO:0016023=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0007352=GO_REF:0000024, GO:0031410=PMID:11113207, GO:0030165=PMID:11113207, GO:0016055=GO_REF:0000019, GO:0003677=GO_REF:0000002} Q9H2H0 CXXC-type zinc finger protein 4 protein 20080926 {GO:0005737=IDA, GO:0030178=IDA, GO:0016023=IEA, GO:0008270=IEA, GO:0007352=ISS, GO:0031410=IDA, GO:0030165=IPI, GO:0016055=IEA, GO:0003677=IEA} Wnt receptor signaling pathway, negative regulation of Wnt receptor signaling pathway, zygotic specification of dorsal/ventral axis cytoplasm, cytoplasmic membrane-bounded vesicle, cytoplasmic vesicle DNA binding, PDZ domain binding, zinc ion binding Human UniProtKB:Q92997 CXXC5 GOC UniProtKB {GO:0007165=PMID:12761501, GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0004871=PMID:12761501, GO:0043123=PMID:12761501, GO:0003677=GO_REF:0000002} Q7LFL8 CXXC-type zinc finger protein 5 protein 20130413 {GO:0007165=IMP, GO:0005737=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0004871=IMP, GO:0043123=IMP, GO:0003677=IEA} positive regulation of I-kappaB kinase/NF-kappaB cascade, signal transduction cytoplasm, nucleus DNA binding, signal transducer activity, zinc ion binding Human CYB561 HGNC UniProtKB {GO:0000293=PMID:14499595, GO:0022865=PMID:7559396, GO:0016021=PMID:7559396, GO:0022900=PMID:7559396, GO:0046872=GO_REF:0000037} P49447 Cytochrome b561 protein 20060201 {GO:0000293=ISS, GO:0022865=NAS, GO:0016021=NAS, GO:0022900=NAS, GO:0046872=IEA} electron transport chain integral to membrane ferric-chelate reductase activity, metal ion binding, transmembrane electron transfer carrier Human UniProtKB:Q60720 CYB561D2 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0022900=GO_REF:0000037, GO:0046872=GO_REF:0000037} O14569 Cytochrome b561 domain-containing protein 2 protein 20130413 {GO:0016021=IEA, GO:0022900=IEA, GO:0046872=IEA} electron transport chain integral to membrane metal ion binding Human UniProtKB-KW:KW-0479 CYB5A BHF-UCL UniProtKB {GO:0004129=PMID:1712589, GO:0006767=Reactome:REACT_11238, GO:0005741=Reactome:REACT_11182, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0005739=GO_REF:0000019, GO:0019852=Reactome:REACT_11202, GO:0004033=Reactome:REACT_11100, GO:0006766=Reactome:REACT_11193, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0019899=PMID:15680923, GO:0022900=GO_REF:0000037, GO:0020037=GO_REF:0000002} P00167 Cytochrome b5 protein 20100205 {GO:0004129=TAS, GO:0006767=TAS, GO:0005741=TAS, GO:0044281=TAS, GO:0046872=IEA, GO:0005739=IEA, GO:0019852=TAS, GO:0004033=TAS, GO:0006766=TAS, GO:0005789=IEA, GO:0016021=IEA, GO:0019899=IPI, GO:0022900=IEA, GO:0020037=IEA} L-ascorbic acid metabolic process, electron transport chain, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process endoplasmic reticulum membrane, integral to membrane, mitochondrial outer membrane, mitochondrion aldo-keto reductase (NADP) activity, cytochrome-c oxidase activity, enzyme binding, heme binding, metal ion binding Human UniProtKB:P08684 CYB5B UniProtKB UniProtKB {GO:0005743=GO_REF:0000019, GO:0005741=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0022900=GO_REF:0000037, GO:0008047=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0020037=PMID:20861021} O43169 Cytochrome b5 type B protein 20111031 {GO:0005743=IEA, GO:0005741=IEA, GO:0016021=IEA, GO:0022900=IEA, GO:0008047=IEA, GO:0046872=IEA, GO:0020037=IDA} electron transport chain integral to membrane, mitochondrial inner membrane, mitochondrial outer membrane enzyme activator activity, heme binding, metal ion binding Human CYB5D1 UniProtKB UniProtKB {GO:0046872=GO_REF:0000037, GO:0020037=GO_REF:0000002} Q6P9G0 Cytochrome b5 domain-containing protein 1 protein 20130413 {GO:0046872=IEA, GO:0020037=IEA} heme binding, metal ion binding Human UniProtKB-KW:KW-0479 CYB5R1 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0004128=GO_REF:0000003, GO:0016126=GO_REF:0000037, GO:0016491=GO_REF:0000038, GO:0016021=GO_REF:0000037} Q9UHQ9 NADH-cytochrome b5 reductase 1 protein 20130413 {GO:0005739=IEA, GO:0004128=IEA, GO:0016126=IEA, GO:0016491=IEA, GO:0016021=IEA} sterol biosynthetic process integral to membrane, mitochondrion cytochrome-b5 reductase activity, acting on NAD(P)H, oxidoreductase activity Human Ensembl:ENSMUSP00000027726 CYB5R2 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0016020=PMID:10611283, GO:0004128=PMID:10611283, GO:0016126=GO_REF:0000037, GO:0016491=GO_REF:0000002, GO:0055114=PMID:10611283} Q6BCY4 NADH-cytochrome b5 reductase 2 protein 20070906 {GO:0005739=IEA, GO:0016020=IDA, GO:0004128=IDA, GO:0016126=IEA, GO:0016491=IEA, GO:0055114=IDA} oxidation-reduction process, sterol biosynthetic process membrane, mitochondrion cytochrome-b5 reductase activity, acting on NAD(P)H, oxidoreductase activity Human CYB5R3 HPA UniProtKB {GO:0006695=GO_REF:0000037, GO:0016208=GO_REF:0000019, GO:0005833=PMID:1400360, GO:0004128=Reactome:REACT_11182, GO:0005783=GO_REF:0000052, GO:0008015=PMID:1400360, GO:0050660=GO_REF:0000019, GO:0005743=GO_REF:0000019, GO:0006767=Reactome:REACT_11238, GO:0005741=Reactome:REACT_11182, GO:0044281=Reactome:REACT_111217, GO:0019852=Reactome:REACT_11202, GO:0005737=PMID:9207238, GO:0051287=GO_REF:0000019, GO:0043531=GO_REF:0000019, GO:0016020=PMID:9207238, GO:0006766=Reactome:REACT_11193, GO:0016491=GO_REF:0000002, GO:0005789=GO_REF:0000039} P00387 NADH-cytochrome b5 reductase 3 protein 20080205 {GO:0006695=IEA, GO:0016208=IEA, GO:0005833=TAS, GO:0004128=TAS, GO:0005783=IDA, GO:0008015=TAS, GO:0050660=IEA, GO:0005743=IEA, GO:0006767=TAS, GO:0005741=TAS, GO:0044281=TAS, GO:0019852=TAS, GO:0005737=TAS, GO:0051287=IEA, GO:0043531=IEA, GO:0016020=TAS, GO:0006766=TAS, GO:0016491=IEA, GO:0005789=IEA} L-ascorbic acid metabolic process, blood circulation, cholesterol biosynthetic process, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cytoplasm, endoplasmic reticulum, endoplasmic reticulum membrane, hemoglobin complex, membrane, mitochondrial inner membrane, mitochondrial outer membrane ADP binding, AMP binding, NAD binding, cytochrome-b5 reductase activity, acting on NAD(P)H, flavin adenine dinucleotide binding, oxidoreductase activity Human CYB5R4 UniProtKB UniProtKB {GO:0048471=PMID:10611283, GO:0004128=PMID:10611283, GO:0005783=PMID:15131110, GO:0006801=PMID:10611283, GO:0006091=PMID:10611283, GO:0042593=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0016653=PMID:15131110, GO:0003032=PMID:10611283, GO:0016174=PMID:15131110, GO:0048468=GO_REF:0000024, GO:0030073=GO_REF:0000024, GO:0046677=GO_REF:0000024, GO:0055114=PMID:15131110, GO:0020037=GO_REF:0000002} Q7L1T6 Cytochrome b5 reductase 4 protein 20080507 {GO:0048471=IDA, GO:0004128=IDA, GO:0005783=IDA, GO:0006801=IDA, GO:0006091=IDA, GO:0042593=ISS, GO:0046872=IEA, GO:0016653=IDA, GO:0003032=NAS, GO:0016174=IDA, GO:0048468=ISS, GO:0030073=ISS, GO:0046677=ISS, GO:0055114=IDA, GO:0020037=IEA} cell development, detection of oxygen, generation of precursor metabolites and energy, glucose homeostasis, insulin secretion, oxidation-reduction process, response to antibiotic, superoxide metabolic process endoplasmic reticulum, perinuclear region of cytoplasm NAD(P)H oxidase activity, cytochrome-b5 reductase activity, acting on NAD(P)H, heme binding, metal ion binding, oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor Human CYBA BHF-UCL UniProtKB {GO:0045730=PMID:2243141, GO:0005515=PMID:11733522, GO:0002474=Reactome:REACT_75820, GO:0017124=PMID:7938008, GO:0030307=GO_REF:0000019, GO:0006801=PMID:2243141, GO:0071480=GO_REF:0000019, GO:0050665=GO_REF:0000024, GO:0030425=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005739=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0006954=PMID:2243141, GO:0071230=GO_REF:0000019, GO:0016175=PMID:1763037, GO:0071356=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0030670=Reactome:REACT_121023, GO:0031667=GO_REF:0000019, GO:0030141=PMID:12005167, GO:0071333=GO_REF:0000019, GO:0090382=Reactome:REACT_121256, GO:0070555=GO_REF:0000019, GO:0042554=PMID:2243141, GO:0005794=GO_REF:0000019, GO:0046982=PMID:12042318, GO:0051701=Reactome:REACT_121237, GO:0042493=GO_REF:0000019, GO:0042590=Reactome:REACT_111119, GO:0009055=PMID:12042318, GO:0014895=GO_REF:0000024, GO:0003106=GO_REF:0000019, GO:0071407=GO_REF:0000019, GO:0001938=GO_REF:0000019, GO:0045087=PMID:2243141, GO:0002479=Reactome:REACT_111174, GO:0017004=PMID:7938008, GO:0043020=PMID:3305576, GO:0022900=GO_REF:0000037, GO:0071260=GO_REF:0000019, GO:0055114=PMID:2243141, GO:0020037=GO_REF:0000002} P13498 Cytochrome b-245 light chain protein 20080811 {GO:0045730=IMP, GO:0005515=IPI, GO:0002474=TAS, GO:0017124=IPI, GO:0030307=IEA, GO:0006801=IMP, GO:0071480=IEA, GO:0050665=ISS, GO:0030425=IEA, GO:0046872=IEA, GO:0005739=IEA, GO:0016324=IEA, GO:0006954=IMP, GO:0071230=IEA, GO:0016175=IMP, GO:0071356=IEA, GO:0043025=IEA, GO:0030670=TAS, GO:0031667=IEA, GO:0030141=TAS, GO:0071333=IEA, GO:0090382=TAS, GO:0070555=IEA, GO:0042554=IMP, GO:0005794=IEA, GO:0046982=IPI, GO:0051701=TAS, GO:0042493=IEA, GO:0042590=TAS, GO:0009055=IDA, GO:0014895=ISS, GO:0003106=IEA, GO:0071407=IEA, GO:0001938=IEA, GO:0045087=IMP, GO:0002479=TAS, GO:0017004=IDA, GO:0043020=IDA, GO:0022900=IEA, GO:0071260=IEA, GO:0055114=IMP, GO:0020037=IEA} antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, cellular response to amino acid stimulus, cellular response to gamma radiation, cellular response to glucose stimulus, cellular response to mechanical stimulus, cellular response to organic cyclic compound, cellular response to tumor necrosis factor, cytochrome complex assembly, electron transport chain, hydrogen peroxide biosynthetic process, inflammatory response, innate immune response, interaction with host, negative regulation of glomerular filtration by angiotensin, oxidation-reduction process, phagosome maturation, positive regulation of cell growth, positive regulation of endothelial cell proliferation, respiratory burst, response to drug, response to interleukin-1, response to nutrient levels, smooth muscle hypertrophy, superoxide anion generation, superoxide metabolic process Golgi apparatus, NADPH oxidase complex, apical plasma membrane, dendrite, mitochondrion, neuronal cell body, phagocytic vesicle membrane, secretory granule SH3 domain binding, electron carrier activity, heme binding, metal ion binding, protein binding, protein heterodimerization activity, superoxide-generating NADPH oxidase activity Human CYBB BHF-UCL UniProtKB {GO:0005515=PMID:3305576, GO:0045730=PMID:9774399, GO:0002474=Reactome:REACT_75820, GO:0005886=GO_REF:0000019, GO:0050660=PMID:9774399, GO:0006801=PMID:12042318, GO:0050665=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005739=GO_REF:0000019, GO:0006954=PMID:7719350, GO:0016175=PMID:12042318, GO:0030670=Reactome:REACT_121023, GO:0090382=Reactome:REACT_121256, GO:0042554=PMID:12042318, GO:0005244=GO_REF:0000037, GO:0051701=Reactome:REACT_121237, GO:0046982=PMID:12042318, GO:0042590=Reactome:REACT_111119, GO:0009055=PMID:12042318, GO:0005887=PMID:15233623, GO:0045087=PMID:9774399, GO:0016491=GO_REF:0000038, GO:0002479=Reactome:REACT_111174, GO:0016021=GO_REF:0000038, GO:0043020=PMID:12716910, GO:0022900=GO_REF:0000037, GO:0020037=PMID:9774399, GO:0055114=PMID:12042318} P04839 Cytochrome b-245 heavy chain protein 20080811 {GO:0005515=IPI, GO:0045730=IMP, GO:0002474=TAS, GO:0005886=IEA, GO:0050660=IMP, GO:0006801=IDA, GO:0050665=IEA, GO:0046872=IEA, GO:0005739=IEA, GO:0006954=TAS, GO:0016175=IDA, GO:0030670=TAS, GO:0090382=TAS, GO:0042554=IDA, GO:0005244=IEA, GO:0051701=TAS, GO:0046982=IPI, GO:0042590=TAS, GO:0009055=IDA, GO:0005887=IDA, GO:0045087=IMP, GO:0016491=IEA, GO:0002479=TAS, GO:0016021=IEA, GO:0043020=TAS, GO:0022900=IEA, GO:0020037=IMP, GO:0055114=IDA} antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, electron transport chain, hydrogen peroxide biosynthetic process, inflammatory response, innate immune response, interaction with host, oxidation-reduction process, phagosome maturation, respiratory burst, superoxide anion generation, superoxide metabolic process NADPH oxidase complex, integral to membrane, integral to plasma membrane, mitochondrion, phagocytic vesicle membrane, plasma membrane electron carrier activity, flavin adenine dinucleotide binding, heme binding, metal ion binding, oxidoreductase activity, protein binding, protein heterodimerization activity, superoxide-generating NADPH oxidase activity, voltage-gated ion channel activity Human CYBRD1 Reactome UniProtKB {GO:0006879=Reactome:REACT_25060, GO:0005886=Reactome:REACT_25114, GO:0000293=PMID:14499595, GO:0010039=GO_REF:0000019, GO:0016722=Reactome:REACT_25114, GO:0031526=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0022900=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0046872=GO_REF:0000037} Q53TN4 Cytochrome b reductase 1 protein 20121220 {GO:0006879=TAS, GO:0005886=TAS, GO:0000293=IDA, GO:0010039=IEA, GO:0016722=TAS, GO:0031526=IEA, GO:0016021=IEA, GO:0022900=IEA, GO:0055085=TAS, GO:0046872=IEA} cellular iron ion homeostasis, electron transport chain, response to iron ion, transmembrane transport brush border membrane, integral to membrane, plasma membrane ferric-chelate reductase activity, metal ion binding, oxidoreductase activity, oxidizing metal ions Human CYC1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0022904=Reactome:REACT_22393, GO:0005737=GO_REF:0000052, GO:0045155=PMID:2536365, GO:0030054=GO_REF:0000052, GO:0005506=GO_REF:0000002, GO:0070469=GO_REF:0000037, GO:0005743=Reactome:REACT_6300, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0020037=GO_REF:0000002} P08574 Cytochrome c1, heme protein, mitochondrial protein 20101115 {GO:0005739=IDA, GO:0022904=TAS, GO:0005737=IDA, GO:0045155=TAS, GO:0030054=IDA, GO:0005506=IEA, GO:0070469=IEA, GO:0005743=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0020037=IEA} respiratory electron transport chain, small molecule metabolic process cell junction, cytoplasm, integral to membrane, mitochondrial inner membrane, mitochondrion, respiratory chain electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity, heme binding, iron ion binding Human CYCS LIFEdb UniProtKB {GO:0005515=PMID:9267021, GO:0008635=Reactome:REACT_607, GO:0005506=GO_REF:0000002, GO:0070469=GO_REF:0000037, GO:0005743=Reactome:REACT_6300, GO:0000159=PMID:8206937, GO:0009055=GO_REF:0000002, GO:0006915=Reactome:REACT_578, GO:0005634=GO_REF:0000054, GO:0044281=Reactome:REACT_111217, GO:0097193=Reactome:REACT_964, GO:0005829=Reactome:REACT_2165, GO:0022904=Reactome:REACT_6305, GO:0005739=GO_REF:0000038, GO:0005758=Reactome:REACT_535, GO:0045155=PMID:8689682, GO:0045333=PMID:10383829, GO:0006309=PMID:8689682, GO:0004722=PMID:8206937, GO:0022900=GO_REF:0000038, GO:0020037=PMID:9515723} P99999 Cytochrome c protein 20100607 {GO:0005515=IPI, GO:0008635=TAS, GO:0005506=IEA, GO:0070469=IEA, GO:0005743=TAS, GO:0000159=TAS, GO:0009055=IEA, GO:0006915=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0097193=TAS, GO:0005829=TAS, GO:0022904=TAS, GO:0005739=IEA, GO:0005758=TAS, GO:0045155=IDA, GO:0045333=TAS, GO:0006309=IMP, GO:0004722=TAS, GO:0022900=IEA, GO:0020037=TAS} activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c, apoptotic DNA fragmentation, apoptotic process, cellular respiration, electron transport chain, intrinsic apoptotic signaling pathway, respiratory electron transport chain, small molecule metabolic process cytosol, mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrion, nucleus, protein phosphatase type 2A complex, respiratory chain electron carrier activity, electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity, heme binding, iron ion binding, protein binding, protein serine/threonine phosphatase activity Human CYFIP1 IntAct UniProtKB {GO:0005515=PMID:18805096, GO:0043005=GO_REF:0000024, GO:0048471=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0008360=GO_REF:0000037, GO:0030032=GO_REF:0000024, GO:0045202=GO_REF:0000037, GO:0048675=PMID:16260607, GO:0001726=GO_REF:0000024, GO:0030027=GO_REF:0000024, GO:0031529=GO_REF:0000024, GO:0048365=GO_REF:0000024, GO:0051015=GO_REF:0000024, GO:0005845=GO_REF:0000024} Q7L576 Cytoplasmic FMR1-interacting protein 1 protein 20130415 {GO:0005515=IPI, GO:0043005=ISS, GO:0048471=ISS, GO:0030054=IEA, GO:0008360=IEA, GO:0030032=ISS, GO:0045202=IEA, GO:0048675=IMP, GO:0001726=ISS, GO:0030027=ISS, GO:0031529=ISS, GO:0048365=ISS, GO:0051015=ISS, GO:0005845=ISS} axon extension, lamellipodium assembly, regulation of cell shape, ruffle organization cell junction, lamellipodium, mRNA cap binding complex, neuron projection, perinuclear region of cytoplasm, ruffle, synapse Rac GTPase binding, actin filament binding, protein binding Human UniProtKB:P63073 CYFIP2 BHF-UCL UniProtKB {GO:0005515=PMID:11438699, GO:0043005=GO_REF:0000039, GO:0048471=PMID:10449408, GO:0030054=GO_REF:0000037, GO:0006915=PMID:10449408, GO:0045202=PMID:11438699, GO:0097202=PMID:18387192, GO:0045862=PMID:18387192, GO:0005829=Reactome:REACT_160291, GO:0005737=PMID:11438699, GO:0016337=PMID:15048733, GO:0045087=Reactome:REACT_6802, GO:0038096=Reactome:REACT_160123} Q96F07 Cytoplasmic FMR1-interacting protein 2 protein 20130219 {GO:0005515=IPI, GO:0043005=IEA, GO:0048471=IDA, GO:0030054=IEA, GO:0006915=IDA, GO:0045202=IDA, GO:0097202=IDA, GO:0045862=IDA, GO:0005829=TAS, GO:0005737=IDA, GO:0016337=IDA, GO:0045087=TAS, GO:0038096=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, activation of cysteine-type endopeptidase activity, apoptotic process, cell-cell adhesion, innate immune response, positive regulation of proteolysis cell junction, cytoplasm, cytosol, neuron projection, perinuclear region of cytoplasm, synapse protein binding Human CYGB UniProtKB UniProtKB {GO:0043005=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0004601=PMID:11320098, GO:0019825=GO_REF:0000002, GO:0005506=GO_REF:0000002, GO:0043025=GO_REF:0000019, GO:0005344=PMID:11919282, GO:0006979=PMID:11320098, GO:0015671=PMID:11919282, GO:0020037=GO_REF:0000002} Q8WWM9 Cytoglobin protein 20061120 {GO:0043005=IEA, GO:0005737=IEA, GO:0004601=ISS, GO:0019825=IEA, GO:0005506=IEA, GO:0043025=IEA, GO:0005344=NAS, GO:0006979=ISS, GO:0015671=NAS, GO:0020037=IEA} oxygen transport, response to oxidative stress cytoplasm, neuron projection, neuronal cell body heme binding, iron ion binding, oxygen binding, oxygen transporter activity, peroxidase activity Human UniProtKB:Q921A4 CYHR1 UniProtKB UniProtKB {GO:0048471=GO_REF:0000039, GO:0005737=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005635=GO_REF:0000019} Q6ZMK1 Cysteine and histidine-rich protein 1 protein 20130413 {GO:0048471=IEA, GO:0005737=IEA, GO:0008270=IEA, GO:0005635=IEA} cytoplasm, nuclear envelope, perinuclear region of cytoplasm zinc ion binding Human UniProtKB-SubCell:SL-0198 CYLC2 UniProtKB UniProtKB {GO:0033150=GO_REF:0000039, GO:0005200=GO_REF:0000002, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q14093 Cylicin-2 protein 20130413 {GO:0033150=IEA, GO:0005200=IEA, GO:0007275=IEA, GO:0007283=IEA, GO:0030154=IEA} cell differentiation, multicellular organismal development, spermatogenesis cytoskeletal calyx structural constituent of cytoskeleton Human UniProtKB-SubCell:SL-0032 CYLD Reactome UniProtKB {GO:0005515=PMID:20227366, GO:0006511=GO_REF:0000002, GO:0005881=PMID:17495026, GO:0042347=PMID:18313383, GO:0048471=GO_REF:0000039, GO:0004843=PMID:18313383, GO:0070423=Reactome:REACT_75776, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_75903, GO:0070536=PMID:18313383, GO:0016055=GO_REF:0000037, GO:0070064=PMID:15341735, GO:0090090=PMID:20227366, GO:0032480=Reactome:REACT_25271, GO:0019901=PMID:17495026, GO:0030496=PMID:17495026, GO:0032088=PMID:18313383, GO:0006917=PMID:21525013, GO:0031234=PMID:20194890, GO:0070507=PMID:20194890, GO:0007346=PMID:17495026, GO:0007049=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0008270=PMID:18313383, GO:0004221=GO_REF:0000002} Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD protein 20130301 {GO:0005515=IPI, GO:0006511=IEA, GO:0005881=IDA, GO:0042347=IDA, GO:0048471=IEA, GO:0004843=IDA, GO:0070423=TAS, GO:0035872=TAS, GO:0005829=TAS, GO:0070536=IDA, GO:0016055=IEA, GO:0070064=IPI, GO:0090090=IMP, GO:0032480=TAS, GO:0019901=IPI, GO:0030496=IDA, GO:0032088=IDA, GO:0006917=IDA, GO:0031234=IDA, GO:0070507=IMP, GO:0007346=IMP, GO:0007049=IEA, GO:0045087=TAS, GO:0008270=IDA, GO:0004221=IEA} Wnt receptor signaling pathway, cell cycle, induction of apoptosis, innate immune response, negative regulation of NF-kappaB import into nucleus, negative regulation of NF-kappaB transcription factor activity, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of type I interferon production, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, nucleotide-binding oligomerization domain containing signaling pathway, protein K63-linked deubiquitination, regulation of microtubule cytoskeleton organization, regulation of mitotic cell cycle, ubiquitin-dependent protein catabolic process cytoplasmic microtubule, cytosol, extrinsic to internal side of plasma membrane, midbody, perinuclear region of cytoplasm proline-rich region binding, protein binding, protein kinase binding, ubiquitin thiolesterase activity, ubiquitin-specific protease activity, zinc ion binding Human CYP11A1 Reactome UniProtKB {GO:0042542=GO_REF:0000019, GO:0006805=Reactome:REACT_13705, GO:0009651=GO_REF:0000019, GO:0018963=GO_REF:0000019, GO:0006701=GO_REF:0000019, GO:0006703=GO_REF:0000019, GO:0071560=GO_REF:0000019, GO:0033591=GO_REF:0000019, GO:0033595=GO_REF:0000019, GO:0014037=GO_REF:0000019, GO:0005759=Reactome:REACT_10084, GO:0060992=GO_REF:0000019, GO:0071356=GO_REF:0000019, GO:0033197=GO_REF:0000019, GO:0018958=GO_REF:0000019, GO:0010332=GO_REF:0000019, GO:0030061=GO_REF:0000019, GO:0051412=GO_REF:0000019, GO:0005506=GO_REF:0000002, GO:0007617=GO_REF:0000019, GO:0042359=GO_REF:0000024, GO:0060135=GO_REF:0000019, GO:0021549=GO_REF:0000019, GO:0043279=GO_REF:0000019, GO:0061370=GO_REF:0000019, GO:0071347=GO_REF:0000019, GO:0006700=Reactome:REACT_11038, GO:0020037=PMID:21636783, GO:0008386=PMID:21636783, GO:0018879=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0071372=GO_REF:0000019, GO:0005739=GO_REF:0000024, GO:0004497=GO_REF:0000002, GO:0015485=GO_REF:0000019, GO:0071375=GO_REF:0000019, GO:0001101=GO_REF:0000019, GO:0043204=GO_REF:0000019, GO:0071276=GO_REF:0000019, GO:0008202=Reactome:REACT_11057, GO:0071236=GO_REF:0000019, GO:0008203=PMID:21636783, GO:0042493=GO_REF:0000019, GO:0009055=GO_REF:0000002, GO:0044344=GO_REF:0000019, GO:0021766=GO_REF:0000019, GO:0050756=GO_REF:0000019, GO:0018894=GO_REF:0000019, GO:0071222=GO_REF:0000019, GO:0033327=GO_REF:0000019, GO:0017085=GO_REF:0000019, GO:0016705=GO_REF:0000002, GO:0071320=GO_REF:0000019, GO:0060014=GO_REF:0000019} P05108 Cholesterol side-chain cleavage enzyme, mitochondrial protein 20130301 {GO:0042542=IEA, GO:0006805=TAS, GO:0009651=IEA, GO:0018963=IEA, GO:0006701=IEA, GO:0006703=IEA, GO:0071560=IEA, GO:0033591=IEA, GO:0033595=IEA, GO:0014037=IEA, GO:0005759=TAS, GO:0060992=IEA, GO:0071356=IEA, GO:0033197=IEA, GO:0018958=IEA, GO:0010332=IEA, GO:0030061=IEA, GO:0051412=IEA, GO:0005506=IEA, GO:0007617=IEA, GO:0042359=ISS, GO:0060135=IEA, GO:0021549=IEA, GO:0043279=IEA, GO:0061370=IEA, GO:0071347=IEA, GO:0006700=TAS, GO:0020037=IDA, GO:0008386=IDA, GO:0018879=IEA, GO:0044281=TAS, GO:0071372=IEA, GO:0005739=ISS, GO:0004497=IEA, GO:0015485=IEA, GO:0071375=IEA, GO:0001101=IEA, GO:0043204=IEA, GO:0071276=IEA, GO:0008202=TAS, GO:0071236=IEA, GO:0008203=IDA, GO:0042493=IEA, GO:0009055=IEA, GO:0044344=IEA, GO:0021766=IEA, GO:0050756=IEA, GO:0018894=IEA, GO:0071222=IEA, GO:0033327=IEA, GO:0017085=IEA, GO:0016705=IEA, GO:0071320=IEA, GO:0060014=IEA} C21-steroid hormone biosynthetic process, Leydig cell differentiation, Schwann cell differentiation, biphenyl metabolic process, cellular response to antibiotic, cellular response to cAMP, cellular response to cadmium ion, cellular response to fibroblast growth factor stimulus, cellular response to follicle-stimulating hormone stimulus, cellular response to interleukin-1, cellular response to lipopolysaccharide, cellular response to peptide hormone stimulus, cellular response to transforming growth factor beta stimulus, cellular response to tumor necrosis factor, cerebellum development, cholesterol metabolic process, dibenzo-p-dioxin metabolic process, estrogen biosynthetic process, fractalkine metabolic process, granulosa cell differentiation, hippocampus development, maternal process involved in female pregnancy, mating behavior, phenol-containing compound metabolic process, phthalate metabolic process, progesterone biosynthetic process, response to L-ascorbic acid, response to acid, response to alkaloid, response to corticosterone stimulus, response to drug, response to fungicide, response to gamma radiation, response to genistein, response to hydrogen peroxide, response to insecticide, response to salt stress, response to vitamin E, small molecule metabolic process, steroid metabolic process, testosterone biosynthetic process, vitamin D metabolic process, xenobiotic metabolic process mitochondrial crista, mitochondrial matrix, mitochondrion, perikaryon cholesterol binding, cholesterol monooxygenase (side-chain-cleaving) activity, electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Human CYP11B1 UniProtKB UniProtKB {GO:0006705=Reactome:REACT_11047, GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0006704=Reactome:REACT_11036, GO:0006950=PMID:12452430, GO:0005743=PMID:8506298, GO:0009055=GO_REF:0000002, GO:0042593=PMID:16114325, GO:0004507=PMID:2256920, GO:0044281=Reactome:REACT_111217, GO:0032870=PMID:19342457, GO:0034651=PMID:2022736, GO:0005739=PMID:2256920, GO:0004497=GO_REF:0000038, GO:0006955=PMID:12452430, GO:0035865=PMID:19342457, GO:0006700=PMID:2256920, GO:0008217=PMID:2022736, GO:0032342=PMID:2256920, GO:0016705=GO_REF:0000002, GO:0008202=Reactome:REACT_11057, GO:0020037=GO_REF:0000002} Q4VAR0 CYP11B1 protein protein 20130413 {GO:0006705=TAS, GO:0006805=TAS, GO:0005506=IEA, GO:0006704=TAS, GO:0006950=TAS, GO:0005743=IC, GO:0009055=IEA, GO:0042593=TAS, GO:0004507=IDA, GO:0044281=TAS, GO:0032870=IEP, GO:0034651=IMP, GO:0005739=IDA, GO:0004497=IEA, GO:0006955=TAS, GO:0035865=IEP, GO:0006700=IDA, GO:0008217=IMP, GO:0032342=IDA, GO:0016705=IEA, GO:0008202=TAS, GO:0020037=IEA} C21-steroid hormone biosynthetic process, aldosterone biosynthetic process, cellular response to hormone stimulus, cellular response to potassium ion, cortisol biosynthetic process, glucocorticoid biosynthetic process, glucose homeostasis, immune response, mineralocorticoid biosynthetic process, regulation of blood pressure, response to stress, small molecule metabolic process, steroid metabolic process, xenobiotic metabolic process mitochondrial inner membrane, mitochondrion electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, steroid 11-beta-monooxygenase activity Human UniProtKB-KW:KW-0503 CYP11B2 BHF-UCL UniProtKB {GO:0006705=Reactome:REACT_11047, GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0055075=PMID:9838244, GO:0005743=PMID:2256920, GO:0009055=GO_REF:0000002, GO:0055078=PMID:9838244, GO:0044281=Reactome:REACT_111217, GO:0047783=GO_REF:0000003, GO:0004507=PMID:1741400, GO:0032870=PMID:19342457, GO:0034651=PMID:9703385, GO:0003091=PMID:2256920, GO:0005739=PMID:1741400, GO:0035865=PMID:19342457, GO:0002017=PMID:14614232, GO:0006700=PMID:2256920, GO:0032342=PMID:1741400, GO:0008202=Reactome:REACT_11057, GO:0020037=PMID:2256920} P19099 Cytochrome P450 11B2, mitochondrial protein 20080812 {GO:0006705=TAS, GO:0006805=TAS, GO:0005506=IEA, GO:0055075=IMP, GO:0005743=IC, GO:0009055=IEA, GO:0055078=IMP, GO:0044281=TAS, GO:0047783=IEA, GO:0004507=IDA, GO:0032870=IEP, GO:0034651=IMP, GO:0003091=IC, GO:0005739=IDA, GO:0035865=IEP, GO:0002017=IMP, GO:0006700=IDA, GO:0032342=IDA, GO:0008202=TAS, GO:0020037=IC} C21-steroid hormone biosynthetic process, aldosterone biosynthetic process, cellular response to hormone stimulus, cellular response to potassium ion, cortisol biosynthetic process, mineralocorticoid biosynthetic process, potassium ion homeostasis, regulation of blood volume by renal aldosterone, renal water homeostasis, small molecule metabolic process, sodium ion homeostasis, steroid metabolic process, xenobiotic metabolic process mitochondrial inner membrane, mitochondrion corticosterone 18-monooxygenase activity, electron carrier activity, heme binding, iron ion binding, steroid 11-beta-monooxygenase activity Human CYP17A1 Reactome UniProtKB {GO:0030424=GO_REF:0000019, GO:0006694=PMID:3500022, GO:0006805=Reactome:REACT_13705, GO:0018963=GO_REF:0000019, GO:0030325=GO_REF:0000019, GO:0006702=Reactome:REACT_11059, GO:0005783=PMID:9326943, GO:0006704=Reactome:REACT_11036, GO:0018879=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0047442=GO_REF:0000003, GO:0051591=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0010034=GO_REF:0000019, GO:0071371=GO_REF:0000019, GO:0060992=GO_REF:0000019, GO:0010212=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0031667=GO_REF:0000019, GO:0007548=PMID:9326943, GO:0090031=GO_REF:0000019, GO:0018958=GO_REF:0000019, GO:0032526=GO_REF:0000019, GO:0034097=GO_REF:0000019, GO:0008202=Reactome:REACT_11057, GO:0071236=GO_REF:0000019, GO:0005506=GO_REF:0000002, GO:0042493=GO_REF:0000019, GO:0009055=GO_REF:0000002, GO:0004508=PMID:22266943, GO:0009635=GO_REF:0000019, GO:0048545=GO_REF:0000019, GO:0021766=GO_REF:0000019, GO:0018894=GO_REF:0000019, GO:0071222=GO_REF:0000019, GO:0019825=PMID:2808364, GO:0051597=GO_REF:0000019, GO:0042448=PMID:22266943, GO:0005789=Reactome:REACT_10116, GO:0042446=PMID:22266943, GO:0033327=GO_REF:0000019, GO:0017085=GO_REF:0000019, GO:0030728=GO_REF:0000019, GO:0020037=PMID:22266943} P05093 Steroid 17-alpha-hydroxylase/17,20 lyase protein 20130301 {GO:0030424=IEA, GO:0006694=TAS, GO:0006805=TAS, GO:0018963=IEA, GO:0030325=IEA, GO:0006702=TAS, GO:0005783=NAS, GO:0006704=TAS, GO:0018879=IEA, GO:0044281=TAS, GO:0047442=IEA, GO:0051591=IEA, GO:0005739=IEA, GO:0010034=IEA, GO:0071371=IEA, GO:0060992=IEA, GO:0010212=IEA, GO:0043025=IEA, GO:0031667=IEA, GO:0007548=TAS, GO:0090031=IEA, GO:0018958=IEA, GO:0032526=IEA, GO:0034097=IEA, GO:0008202=TAS, GO:0071236=IEA, GO:0005506=IEA, GO:0042493=IEA, GO:0009055=IEA, GO:0004508=IDA, GO:0009635=IEA, GO:0048545=IEA, GO:0021766=IEA, GO:0018894=IEA, GO:0071222=IEA, GO:0019825=TAS, GO:0051597=IEA, GO:0042448=IDA, GO:0005789=TAS, GO:0042446=IDA, GO:0033327=IEA, GO:0017085=IEA, GO:0030728=IEA, GO:0020037=IDA} Leydig cell differentiation, adrenal gland development, androgen biosynthetic process, biphenyl metabolic process, cellular response to antibiotic, cellular response to gonadotropin stimulus, cellular response to lipopolysaccharide, dibenzo-p-dioxin metabolic process, glucocorticoid biosynthetic process, hippocampus development, hormone biosynthetic process, ovulation, phenol-containing compound metabolic process, phthalate metabolic process, positive regulation of steroid hormone biosynthetic process, progesterone metabolic process, response to acetate, response to cAMP, response to cytokine stimulus, response to drug, response to fungicide, response to herbicide, response to insecticide, response to ionizing radiation, response to methylmercury, response to nutrient levels, response to retinoic acid, response to steroid hormone stimulus, sex differentiation, small molecule metabolic process, steroid biosynthetic process, steroid metabolic process, xenobiotic metabolic process axon, endoplasmic reticulum, endoplasmic reticulum membrane, mitochondrion, neuronal cell body 17-alpha-hydroxyprogesterone aldolase activity, electron carrier activity, heme binding, iron ion binding, oxygen binding, steroid 17-alpha-monooxygenase activity Human CYP19A1 InterPro UniProtKB {GO:0006694=PMID:2848247, GO:0006805=Reactome:REACT_13705, GO:0060736=GO_REF:0000019, GO:0005506=GO_REF:0000002, GO:0070330=PMID:19129847, GO:0005783=GO_REF:0000054, GO:0008209=GO_REF:0000019, GO:0006703=Reactome:REACT_11037, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0016020=PMID:2848247, GO:0019825=PMID:2848247, GO:0005789=Reactome:REACT_9963, GO:0016712=PMID:1371509, GO:0016705=GO_REF:0000002, GO:0008202=Reactome:REACT_11057, GO:0020037=GO_REF:0000002} Q8IYJ7 CYP19A1 protein protein 20130413 {GO:0006694=TAS, GO:0006805=TAS, GO:0060736=IEA, GO:0005506=IEA, GO:0070330=IDA, GO:0005783=IDA, GO:0008209=IEA, GO:0006703=TAS, GO:0009055=IEA, GO:0044281=TAS, GO:0016020=TAS, GO:0019825=TAS, GO:0005789=TAS, GO:0016712=TAS, GO:0016705=IEA, GO:0008202=TAS, GO:0020037=IEA} androgen metabolic process, estrogen biosynthetic process, prostate gland growth, small molecule metabolic process, steroid biosynthetic process, steroid metabolic process, xenobiotic metabolic process endoplasmic reticulum, endoplasmic reticulum membrane, membrane aromatase activity, electron carrier activity, heme binding, iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen, oxygen binding Human InterPro:IPR001128 CYP1A1 BHF-UCL UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0014070=GO_REF:0000019, GO:0046685=GO_REF:0000019, GO:0006805=Reactome:REACT_13705, GO:0017144=PMID:19219744, GO:0017143=GO_REF:0000019, GO:0033189=GO_REF:0000019, GO:0009792=GO_REF:0000019, GO:0010041=GO_REF:0000019, GO:0016711=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0070576=PMID:15546903, GO:0016712=GO_REF:0000002, GO:0046677=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0005506=GO_REF:0000002, GO:0070330=GO_REF:0000003, GO:0042359=PMID:15546903, GO:0007568=GO_REF:0000019, GO:0060137=GO_REF:0000019, GO:0009635=GO_REF:0000019, GO:0006778=GO_REF:0000019, GO:0097267=Reactome:REACT_150134, GO:0055093=GO_REF:0000019, GO:0016491=PMID:19219744, GO:0005789=Reactome:REACT_150442, GO:0045750=GO_REF:0000019, GO:0019899=GO_REF:0000019, GO:0055114=PMID:19219744, GO:0020037=GO_REF:0000002, GO:0008283=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0009624=GO_REF:0000019, GO:0050665=GO_REF:0000019, GO:0032094=GO_REF:0000019, GO:0019341=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0043010=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0019373=Reactome:REACT_150417, GO:0008395=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0016679=GO_REF:0000019, GO:0009611=GO_REF:0000019, GO:0009055=GO_REF:0000002, GO:0009804=GO_REF:0000019, GO:0048565=GO_REF:0000019, GO:0009615=GO_REF:0000019, GO:0032451=GO_REF:0000019, GO:0009812=GO_REF:0000019, GO:0019825=PMID:1691986, GO:0042904=GO_REF:0000019, GO:0009308=GO_REF:0000019, GO:0070365=GO_REF:0000019} P04798 Cytochrome P450 1A1 protein 20090629 {GO:0019369=TAS, GO:0014070=IEA, GO:0046685=IEA, GO:0006805=TAS, GO:0017144=IDA, GO:0017143=IEA, GO:0033189=IEA, GO:0009792=IEA, GO:0010041=IEA, GO:0016711=IEA, GO:0032496=IEA, GO:0070576=IDA, GO:0016712=IEA, GO:0046677=IEA, GO:0044255=TAS, GO:0005506=IEA, GO:0070330=IEA, GO:0042359=IC, GO:0007568=IEA, GO:0060137=IEA, GO:0009635=IEA, GO:0006778=IEA, GO:0097267=TAS, GO:0055093=IEA, GO:0016491=IDA, GO:0005789=TAS, GO:0045750=IEA, GO:0019899=IEA, GO:0055114=IDA, GO:0020037=IEA, GO:0008283=IEA, GO:0044281=TAS, GO:0009624=IEA, GO:0050665=IEA, GO:0032094=IEA, GO:0019341=IEA, GO:0005739=IEA, GO:0043010=IEA, GO:0001666=IEA, GO:0019373=TAS, GO:0008395=IEA, GO:0042493=IEA, GO:0016679=IEA, GO:0009611=IEA, GO:0009055=IEA, GO:0009804=IEA, GO:0048565=IEA, GO:0009615=IEA, GO:0032451=IEA, GO:0009812=IEA, GO:0019825=TAS, GO:0042904=IEA, GO:0009308=IEA, GO:0070365=IEA} 9-cis-retinoic acid biosynthetic process, aging, amine metabolic process, arachidonic acid metabolic process, camera-type eye development, cell proliferation, cellular lipid metabolic process, coumarin metabolic process, dibenzo-p-dioxin catabolic process, digestive tract development, drug metabolic process, embryo development ending in birth or egg hatching, epoxygenase P450 pathway, flavonoid metabolic process, hepatocyte differentiation, hydrogen peroxide biosynthetic process, insecticide metabolic process, maternal process involved in parturition, omega-hydroxylase P450 pathway, oxidation-reduction process, porphyrin-containing compound metabolic process, positive regulation of S phase of mitotic cell cycle, response to antibiotic, response to arsenic-containing substance, response to drug, response to food, response to herbicide, response to hyperoxia, response to hypoxia, response to iron(III) ion, response to lipopolysaccharide, response to nematode, response to organic cyclic compound, response to virus, response to vitamin A, response to wounding, small molecule metabolic process, vitamin D metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane, mitochondrion aromatase activity, demethylase activity, electron carrier activity, enzyme binding, flavonoid 3'-monooxygenase activity, heme binding, iron ion binding, oxidoreductase activity, oxidoreductase activity, acting on diphenols and related substances as donors, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen, oxygen binding, steroid hydroxylase activity, vitamin D 24-hydroxylase activity Human GO:0070576 CYP1A2 BHF-UCL UniProtKB {GO:0010468=GO_REF:0000019, GO:0019369=Reactome:REACT_147851, GO:0034875=PMID:18619574, GO:0006706=PMID:18356043, GO:0006805=Reactome:REACT_13705, GO:0017144=PMID:15327587, GO:0030324=GO_REF:0000019, GO:0070989=PMID:18619574, GO:0071615=PMID:19029318, GO:0044281=Reactome:REACT_111217, GO:0050665=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0032259=Reactome:REACT_6946, GO:0043231=PMID:2813353, GO:0004497=PMID:15327587, GO:0032787=PMID:19651758, GO:0009820=PMID:11511187, GO:0032496=GO_REF:0000019, GO:0016712=PMID:2813353, GO:0071276=GO_REF:0000019, GO:0032355=GO_REF:0000019, GO:0046483=PMID:15327587, GO:0070330=GO_REF:0000003, GO:0005506=GO_REF:0000002, GO:0019373=Reactome:REACT_150417, GO:0006950=GO_REF:0000019, GO:0009055=PMID:2813353, GO:0016098=PMID:16401082, GO:0018894=GO_REF:0000019, GO:0045333=GO_REF:0000019, GO:0032451=PMID:2813353, GO:0042737=PMID:18356043, GO:0006778=GO_REF:0000019, GO:0042738=PMID:18619574, GO:0097267=Reactome:REACT_150134, GO:0016491=PMID:16401082, GO:0005789=Reactome:REACT_150442, GO:0009403=PMID:11511187, GO:0019899=PMID:15680923, GO:0055114=PMID:16401082, GO:0020037=PMID:17311915} P05177 Cytochrome P450 1A2 protein 20100203 {GO:0010468=IEA, GO:0019369=TAS, GO:0034875=IDA, GO:0006706=IMP, GO:0006805=TAS, GO:0017144=IDA, GO:0030324=IEA, GO:0070989=IDA, GO:0071615=IDA, GO:0044281=TAS, GO:0050665=IEA, GO:0009791=IEA, GO:0032259=TAS, GO:0043231=IDA, GO:0004497=IDA, GO:0032787=IDA, GO:0009820=IDA, GO:0032496=IEA, GO:0016712=IMP, GO:0071276=IEA, GO:0032355=IEA, GO:0046483=IDA, GO:0070330=IEA, GO:0005506=IEA, GO:0019373=TAS, GO:0006950=IEA, GO:0009055=TAS, GO:0016098=IDA, GO:0018894=IEA, GO:0045333=IEA, GO:0032451=IDA, GO:0042737=IMP, GO:0006778=IEA, GO:0042738=IDA, GO:0097267=TAS, GO:0016491=IDA, GO:0005789=TAS, GO:0009403=IDA, GO:0019899=IPI, GO:0055114=IDA, GO:0020037=IDA} alkaloid metabolic process, arachidonic acid metabolic process, cellular respiration, cellular response to cadmium ion, dibenzo-p-dioxin metabolic process, drug catabolic process, drug metabolic process, epoxygenase P450 pathway, exogenous drug catabolic process, heterocycle metabolic process, hydrogen peroxide biosynthetic process, lung development, methylation, monocarboxylic acid metabolic process, monoterpenoid metabolic process, omega-hydroxylase P450 pathway, oxidation-reduction process, oxidative deethylation, oxidative demethylation, porphyrin-containing compound metabolic process, post-embryonic development, regulation of gene expression, response to estradiol stimulus, response to lipopolysaccharide, response to stress, small molecule metabolic process, steroid catabolic process, toxin biosynthetic process, xenobiotic metabolic process endoplasmic reticulum membrane, intracellular membrane-bounded organelle aromatase activity, caffeine oxidase activity, demethylase activity, electron carrier activity, enzyme binding, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen Human CYP1B1 Reactome UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0006725=GO_REF:0000019, GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0070330=GO_REF:0000003, GO:0019373=Reactome:REACT_150417, GO:0061298=GO_REF:0000019, GO:0009055=GO_REF:0000002, GO:0009636=GO_REF:0000019, GO:0071603=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0001525=GO_REF:0000019, GO:0004497=PMID:9097971, GO:0019825=PMID:9097971, GO:0043542=GO_REF:0000019, GO:0097267=Reactome:REACT_150134, GO:0005789=Reactome:REACT_150442, GO:0016712=PMID:10871058, GO:0009404=GO_REF:0000019, GO:0007601=PMID:9097971, GO:0008202=PMID:22888116, GO:0020037=PMID:21147782, GO:0055114=PMID:9097971} Q16678 Cytochrome P450 1B1 protein 20130301 {GO:0019369=TAS, GO:0006725=IEA, GO:0006805=TAS, GO:0005506=IEA, GO:0070330=IEA, GO:0019373=TAS, GO:0061298=IEA, GO:0009055=IEA, GO:0009636=IEA, GO:0071603=IEA, GO:0044281=TAS, GO:0001525=IEA, GO:0004497=TAS, GO:0019825=TAS, GO:0043542=IEA, GO:0097267=TAS, GO:0005789=TAS, GO:0016712=IDA, GO:0009404=IEA, GO:0007601=TAS, GO:0008202=IDA, GO:0020037=IDA, GO:0055114=TAS} angiogenesis, arachidonic acid metabolic process, cellular aromatic compound metabolic process, endothelial cell migration, endothelial cell-cell adhesion, epoxygenase P450 pathway, omega-hydroxylase P450 pathway, oxidation-reduction process, response to toxic substance, retina vasculature development in camera-type eye, small molecule metabolic process, steroid metabolic process, toxin metabolic process, visual perception, xenobiotic metabolic process endoplasmic reticulum membrane aromatase activity, electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen, oxygen binding Human CYP20A1 UniProtKB UniProtKB {GO:0004497=GO_REF:0000037, GO:0005506=GO_REF:0000002, GO:0009055=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0016705=GO_REF:0000002, GO:0020037=GO_REF:0000002} Q6UW02 Cytochrome P450 20A1 protein 20130413 {GO:0004497=IEA, GO:0005506=IEA, GO:0009055=IEA, GO:0016021=IEA, GO:0016705=IEA, GO:0020037=IEA} integral to membrane electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Human UniProtKB-KW:KW-0812 CYP21A2 Reactome UniProtKB {GO:0006705=Reactome:REACT_11047, GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0004509=GO_REF:0000003, GO:0008395=PMID:1406709, GO:0006704=Reactome:REACT_11036, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0005789=Reactome:REACT_10032, GO:0016705=GO_REF:0000002, GO:0005496=GO_REF:0000037, GO:0008202=Reactome:REACT_11057, GO:0020037=GO_REF:0000002} P08686 Steroid 21-hydroxylase protein 20130301 {GO:0006705=TAS, GO:0006805=TAS, GO:0005506=IEA, GO:0004509=IEA, GO:0008395=TAS, GO:0006704=TAS, GO:0009055=IEA, GO:0044281=TAS, GO:0005789=TAS, GO:0016705=IEA, GO:0005496=IEA, GO:0008202=TAS, GO:0020037=IEA} glucocorticoid biosynthetic process, mineralocorticoid biosynthetic process, small molecule metabolic process, steroid metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane electron carrier activity, heme binding, iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, steroid 21-monooxygenase activity, steroid binding, steroid hydroxylase activity Human CYP24A1 BHF-UCL UniProtKB {GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0030342=PMID:8506296, GO:0042359=Reactome:REACT_13523, GO:0042369=PMID:16720713, GO:0005743=Reactome:REACT_13822, GO:0009055=GO_REF:0000002, GO:0033280=PMID:16720713, GO:0044281=Reactome:REACT_111217, GO:0001649=PMID:17023519, GO:0070561=PMID:16720713, GO:0006766=Reactome:REACT_13450, GO:0016491=PMID:7632726, GO:0008403=GO_REF:0000019, GO:0008202=Reactome:REACT_11057, GO:0055114=PMID:8506296, GO:0020037=PMID:8506296} Q07973 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial protein 20090507 {GO:0006805=TAS, GO:0005506=IEA, GO:0030342=IDA, GO:0042359=TAS, GO:0042369=NAS, GO:0005743=TAS, GO:0009055=IEA, GO:0033280=IDA, GO:0044281=TAS, GO:0001649=IEP, GO:0070561=NAS, GO:0006766=TAS, GO:0016491=NAS, GO:0008403=IEA, GO:0008202=TAS, GO:0055114=IDA, GO:0020037=TAS} osteoblast differentiation, oxidation-reduction process, response to vitamin D, small molecule metabolic process, steroid metabolic process, vitamin D catabolic process, vitamin D metabolic process, vitamin D receptor signaling pathway, vitamin metabolic process, xenobiotic metabolic process mitochondrial inner membrane 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity, 25-hydroxycholecalciferol-24-hydroxylase activity, electron carrier activity, heme binding, iron ion binding, oxidoreductase activity Human CYP26B1 BHF-UCL UniProtKB {GO:0006805=Reactome:REACT_13705, GO:0071300=GO_REF:0000019, GO:0005783=GO_REF:0000029, GO:0009954=GO_REF:0000024, GO:0030326=GO_REF:0000024, GO:0007283=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:2001037=GO_REF:0000019, GO:0005506=GO_REF:0000002, GO:0001709=GO_REF:0000024, GO:0009055=GO_REF:0000002, GO:0010628=GO_REF:0000019, GO:0048384=GO_REF:0000019, GO:0006766=Reactome:REACT_13450, GO:0048387=PMID:14532297, GO:0034653=PMID:10823918, GO:0060349=PMID:22019272, GO:0001972=PMID:10823918, GO:0008401=PMID:10823918, GO:0005789=Reactome:REACT_13550, GO:0016705=GO_REF:0000002, GO:0043587=GO_REF:0000019, GO:0007140=GO_REF:0000024, GO:0020037=PMID:10823918, GO:0055114=PMID:10823918} Q9NR63 Cytochrome P450 26B1 protein 20080902 {GO:0006805=TAS, GO:0071300=IEA, GO:0005783=NAS, GO:0009954=ISS, GO:0030326=ISS, GO:0007283=ISS, GO:0044281=TAS, GO:2001037=IEA, GO:0005506=IEA, GO:0001709=ISS, GO:0009055=IEA, GO:0010628=IEA, GO:0048384=IEA, GO:0006766=TAS, GO:0048387=TAS, GO:0034653=IDA, GO:0060349=IMP, GO:0001972=IDA, GO:0008401=IDA, GO:0005789=TAS, GO:0016705=IEA, GO:0043587=IEA, GO:0007140=ISS, GO:0020037=NAS, GO:0055114=IDA} bone morphogenesis, cell fate determination, cellular response to retinoic acid, embryonic limb morphogenesis, male meiosis, negative regulation of retinoic acid receptor signaling pathway, oxidation-reduction process, positive regulation of gene expression, positive regulation of tongue muscle cell differentiation, proximal/distal pattern formation, retinoic acid catabolic process, retinoic acid receptor signaling pathway, small molecule metabolic process, spermatogenesis, tongue morphogenesis, vitamin metabolic process, xenobiotic metabolic process endoplasmic reticulum, endoplasmic reticulum membrane electron carrier activity, heme binding, iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, retinoic acid 4-hydroxylase activity, retinoic acid binding Human UniProtKB:Q811W2 CYP26C1 BHF-UCL UniProtKB {GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0048284=GO_REF:0000024, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0009952=GO_REF:0000024, GO:0007417=GO_REF:0000024, GO:0014032=GO_REF:0000024, GO:0006766=Reactome:REACT_13450, GO:0048387=PMID:14532297, GO:0034653=PMID:14532297, GO:0001972=PMID:14532297, GO:0005789=Reactome:REACT_13793, GO:0008401=PMID:14532297, GO:0016021=GO_REF:0000037, GO:0055114=PMID:14532297, GO:0020037=GO_REF:0000002} Q6V0L0 Cytochrome P450 26C1 protein 20080902 {GO:0006805=TAS, GO:0005506=IEA, GO:0048284=ISS, GO:0009055=IEA, GO:0044281=TAS, GO:0009952=ISS, GO:0007417=ISS, GO:0014032=ISS, GO:0006766=TAS, GO:0048387=NAS, GO:0034653=IDA, GO:0001972=IDA, GO:0005789=TAS, GO:0008401=IDA, GO:0016021=IEA, GO:0055114=IDA, GO:0020037=IEA} anterior/posterior pattern specification, central nervous system development, negative regulation of retinoic acid receptor signaling pathway, neural crest cell development, organelle fusion, oxidation-reduction process, retinoic acid catabolic process, small molecule metabolic process, vitamin metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane, integral to membrane electron carrier activity, heme binding, iron ion binding, retinoic acid 4-hydroxylase activity, retinoic acid binding Human CYP27A1 Reactome UniProtKB {GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0030343=GO_REF:0000019, GO:0006699=Reactome:REACT_11054, GO:0008395=PMID:9790667, GO:0005743=GO_REF:0000019, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0031073=GO_REF:0000019, GO:0047749=GO_REF:0000003, GO:0005759=Reactome:REACT_10104, GO:0008206=Reactome:REACT_11040, GO:0016705=GO_REF:0000002, GO:0020037=GO_REF:0000002, GO:0008203=GO_REF:0000019} Q02318 Sterol 26-hydroxylase, mitochondrial protein 20130301 {GO:0006805=TAS, GO:0005506=IEA, GO:0030343=IEA, GO:0006699=TAS, GO:0008395=TAS, GO:0005743=IEA, GO:0009055=IEA, GO:0044281=TAS, GO:0031073=IEA, GO:0047749=IEA, GO:0005759=TAS, GO:0008206=TAS, GO:0016705=IEA, GO:0020037=IEA, GO:0008203=IEA} bile acid biosynthetic process, bile acid metabolic process, cholesterol metabolic process, small molecule metabolic process, xenobiotic metabolic process mitochondrial inner membrane, mitochondrial matrix cholestanetriol 26-monooxygenase activity, cholesterol 26-hydroxylase activity, electron carrier activity, heme binding, iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, steroid hydroxylase activity, vitamin D3 25-hydroxylase activity Human CYP27B1 BHF-UCL UniProtKB {GO:0030308=PMID:12496369, GO:0043627=PMID:15795327, GO:0006805=Reactome:REACT_13705, GO:0008285=PMID:16549446, GO:0042368=PMID:16549446, GO:0042369=GO_REF:0000019, GO:0005741=Reactome:REACT_13628, GO:0033280=PMID:17426122, GO:0030282=PMID:17023519, GO:0044281=Reactome:REACT_111217, GO:0055074=PMID:9415400, GO:0005739=PMID:9333115, GO:0004498=PMID:9415400, GO:0046697=PMID:16720713, GO:0010980=PMID:16549446, GO:0005737=PMID:16720713, GO:0045618=PMID:12496369, GO:0032496=PMID:12855575, GO:0006816=GO_REF:0000024, GO:0034341=PMID:9282826, GO:0008202=Reactome:REACT_11057, GO:0030500=PMID:9415400, GO:0005506=GO_REF:0000002, GO:0042359=PMID:9415400, GO:0009055=GO_REF:0000002, GO:0070314=PMID:12496369, GO:0006766=Reactome:REACT_13450, GO:0034612=PMID:1690216, GO:0010956=PMID:16549446, GO:0070564=PMID:16549446, GO:0020037=GO_REF:0000002} O15528 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial protein 20090624 {GO:0030308=IMP, GO:0043627=IEP, GO:0006805=TAS, GO:0008285=IDA, GO:0042368=IDA, GO:0042369=IEA, GO:0005741=TAS, GO:0033280=IEP, GO:0030282=IEP, GO:0044281=TAS, GO:0055074=IMP, GO:0005739=TAS, GO:0004498=IDA, GO:0046697=IEP, GO:0010980=IDA, GO:0005737=IDA, GO:0045618=IMP, GO:0032496=IEP, GO:0006816=ISS, GO:0034341=IDA, GO:0008202=TAS, GO:0030500=IMP, GO:0005506=IEA, GO:0042359=IDA, GO:0009055=IEA, GO:0070314=IMP, GO:0006766=TAS, GO:0034612=IEP, GO:0010956=IDA, GO:0070564=IDA, GO:0020037=IEA} G1 to G0 transition, bone mineralization, calcium ion homeostasis, calcium ion transport, decidualization, negative regulation of calcidiol 1-monooxygenase activity, negative regulation of cell growth, negative regulation of cell proliferation, positive regulation of keratinocyte differentiation, positive regulation of vitamin D 24-hydroxylase activity, positive regulation of vitamin D receptor signaling pathway, regulation of bone mineralization, response to estrogen stimulus, response to interferon-gamma, response to lipopolysaccharide, response to tumor necrosis factor, response to vitamin D, small molecule metabolic process, steroid metabolic process, vitamin D biosynthetic process, vitamin D catabolic process, vitamin D metabolic process, vitamin metabolic process, xenobiotic metabolic process cytoplasm, mitochondrial outer membrane, mitochondrion calcidiol 1-monooxygenase activity, electron carrier activity, heme binding, iron ion binding Human CYP27C1 UniProtKB UniProtKB {GO:0004497=GO_REF:0000037, GO:0016020=GO_REF:0000039, GO:0005506=GO_REF:0000002, GO:0009055=GO_REF:0000002, GO:0016705=GO_REF:0000002, GO:0020037=GO_REF:0000002} Q4G0S4 Cytochrome P450 27C1 protein 20130413 {GO:0004497=IEA, GO:0016020=IEA, GO:0005506=IEA, GO:0009055=IEA, GO:0016705=IEA, GO:0020037=IEA} membrane electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Human UniProtKB-SubCell:SL-0162 CYP2A6 BHF-UCL UniProtKB {GO:0005881=PMID:23264731, GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0017144=PMID:19651758, GO:0009055=GO_REF:0000002, GO:0009804=PMID:19651758, GO:0008389=PMID:19029318, GO:0044281=Reactome:REACT_111217, GO:0046226=PMID:19029318, GO:0042738=PMID:15680923, GO:0005789=Reactome:REACT_572, GO:0016712=GO_REF:0000002, GO:0016705=GO_REF:0000002, GO:0019899=PMID:15680923, GO:0008202=PMID:18356043, GO:0020037=PMID:16086027} P11509 Cytochrome P450 2A6 protein 20100204 {GO:0005881=IDA, GO:0006805=TAS, GO:0005506=IEA, GO:0017144=IDA, GO:0009055=IEA, GO:0009804=IDA, GO:0008389=IDA, GO:0044281=TAS, GO:0046226=IDA, GO:0042738=IDA, GO:0005789=TAS, GO:0016712=IEA, GO:0016705=IEA, GO:0019899=IPI, GO:0008202=IMP, GO:0020037=IDA} coumarin catabolic process, coumarin metabolic process, drug metabolic process, exogenous drug catabolic process, small molecule metabolic process, steroid metabolic process, xenobiotic metabolic process cytoplasmic microtubule, endoplasmic reticulum membrane coumarin 7-hydroxylase activity, electron carrier activity, enzyme binding, heme binding, iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen Human CYP2B6 BHF-UCL UniProtKB {GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0017144=PMID:18356043, GO:0005783=GO_REF:0000029, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0043231=GO_REF:0000029, GO:0004497=PMID:19651758, GO:0042738=PMID:19029318, GO:0005789=Reactome:REACT_13515, GO:0016712=GO_REF:0000002, GO:0016705=GO_REF:0000002, GO:0042180=PMID:19651758, GO:0008202=PMID:18356043, GO:0020037=PMID:20061448, GO:0055114=PMID:19651758} P20813 Cytochrome P450 2B6 protein 20100204 {GO:0006805=TAS, GO:0005506=IEA, GO:0017144=IMP, GO:0005783=NAS, GO:0009055=IEA, GO:0044281=TAS, GO:0043231=NAS, GO:0004497=IDA, GO:0042738=IDA, GO:0005789=TAS, GO:0016712=IEA, GO:0016705=IEA, GO:0042180=IDA, GO:0008202=IMP, GO:0020037=IDA, GO:0055114=IDA} cellular ketone metabolic process, drug metabolic process, exogenous drug catabolic process, oxidation-reduction process, small molecule metabolic process, steroid metabolic process, xenobiotic metabolic process endoplasmic reticulum, endoplasmic reticulum membrane, intracellular membrane-bounded organelle electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen Human CYP2C18 Reactome UniProtKB {GO:0004497=PMID:8110777, GO:0006805=Reactome:REACT_13705, GO:0019825=PMID:8110777, GO:0070330=GO_REF:0000003, GO:0005506=GO_REF:0000002, GO:0005789=Reactome:REACT_13729, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0020037=GO_REF:0000002} P33260 Cytochrome P450 2C18 protein 20130301 {GO:0004497=TAS, GO:0006805=TAS, GO:0019825=TAS, GO:0070330=IEA, GO:0005506=IEA, GO:0005789=TAS, GO:0009055=IEA, GO:0044281=TAS, GO:0020037=IEA} small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane aromatase activity, electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxygen binding Human CYP2C19 BHF-UCL UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0018676=GO_REF:0000003, GO:0006805=Reactome:REACT_13705, GO:0017144=PMID:19651758, GO:0005506=GO_REF:0000002, GO:0008395=PMID:18356043, GO:0018675=GO_REF:0000003, GO:0019373=Reactome:REACT_150417, GO:0009055=GO_REF:0000002, GO:0016098=PMID:16401082, GO:0052741=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0043231=PMID:3442670, GO:0004497=PMID:19651758, GO:0019825=PMID:3442670, GO:0042738=PMID:19029318, GO:0097267=Reactome:REACT_150134, GO:0016491=PMID:16401082, GO:0005789=Reactome:REACT_150441, GO:0019899=PMID:15680923, GO:0008202=PMID:18356043, GO:0046483=PMID:19651758, GO:0055114=PMID:16401082, GO:0020037=PMID:23118231} P33261 Cytochrome P450 2C19 protein 20100204 {GO:0019369=TAS, GO:0018676=IEA, GO:0006805=TAS, GO:0017144=IDA, GO:0005506=IEA, GO:0008395=IMP, GO:0018675=IEA, GO:0019373=TAS, GO:0009055=IEA, GO:0016098=IDA, GO:0052741=IEA, GO:0044281=TAS, GO:0043231=TAS, GO:0004497=IDA, GO:0019825=TAS, GO:0042738=IDA, GO:0097267=TAS, GO:0016491=IDA, GO:0005789=TAS, GO:0019899=IPI, GO:0008202=IMP, GO:0046483=IDA, GO:0055114=IDA, GO:0020037=IDA} arachidonic acid metabolic process, drug metabolic process, epoxygenase P450 pathway, exogenous drug catabolic process, heterocycle metabolic process, monoterpenoid metabolic process, omega-hydroxylase P450 pathway, oxidation-reduction process, small molecule metabolic process, steroid metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane, intracellular membrane-bounded organelle (R)-limonene 6-monooxygenase activity, (S)-limonene 6-monooxygenase activity, (S)-limonene 7-monooxygenase activity, electron carrier activity, enzyme binding, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, oxygen binding, steroid hydroxylase activity Human CYP2C8 BHF-UCL UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0034875=PMID:18619574, GO:0006805=Reactome:REACT_13705, GO:0017144=PMID:19651758, GO:0005506=GO_REF:0000002, GO:0070330=GO_REF:0000003, GO:0005783=GO_REF:0000029, GO:0019373=Reactome:REACT_150417, GO:0070989=PMID:18619574, GO:0009055=GO_REF:0000002, GO:0006082=PMID:19651758, GO:0044281=Reactome:REACT_111217, GO:0004497=PMID:19651758, GO:0042738=PMID:18619574, GO:0097267=Reactome:REACT_150134, GO:0005789=Reactome:REACT_150441, GO:0016705=GO_REF:0000002, GO:0055114=PMID:19651758, GO:0020037=GO_REF:0000002} P10632 Cytochrome P450 2C8 protein 20100203 {GO:0019369=TAS, GO:0034875=IDA, GO:0006805=TAS, GO:0017144=IDA, GO:0005506=IEA, GO:0070330=IEA, GO:0005783=NAS, GO:0019373=TAS, GO:0070989=IDA, GO:0009055=IEA, GO:0006082=IDA, GO:0044281=TAS, GO:0004497=IDA, GO:0042738=IDA, GO:0097267=TAS, GO:0005789=TAS, GO:0016705=IEA, GO:0055114=IDA, GO:0020037=IEA} arachidonic acid metabolic process, drug metabolic process, epoxygenase P450 pathway, exogenous drug catabolic process, omega-hydroxylase P450 pathway, organic acid metabolic process, oxidation-reduction process, oxidative demethylation, small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum, endoplasmic reticulum membrane aromatase activity, caffeine oxidase activity, electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Human CYP2C9 BHF-UCL UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0034875=PMID:18619574, GO:0018676=GO_REF:0000003, GO:0006805=Reactome:REACT_13705, GO:0017144=PMID:19651758, GO:0005783=GO_REF:0000029, GO:0018675=GO_REF:0000003, GO:0070989=PMID:18619574, GO:0044281=Reactome:REACT_111217, GO:0043603=PMID:19651758, GO:0043231=PMID:3032244, GO:0004497=PMID:19651758, GO:0032787=PMID:19651758, GO:0008144=PMID:19448135, GO:0019627=PMID:19029318, GO:0008202=PMID:18356043, GO:0005506=GO_REF:0000002, GO:0019373=Reactome:REACT_150417, GO:0008395=PMID:18356043, GO:0009055=GO_REF:0000002, GO:0016098=PMID:16401082, GO:0052741=GO_REF:0000003, GO:0042737=PMID:18356043, GO:0042738=PMID:18619574, GO:0097267=Reactome:REACT_150134, GO:0005789=Reactome:REACT_150441, GO:0016491=PMID:16401082, GO:0020037=GO_REF:0000002, GO:0055114=PMID:16401082} P11712 Cytochrome P450 2C9 protein 20100203 {GO:0019369=TAS, GO:0034875=IDA, GO:0018676=IEA, GO:0006805=TAS, GO:0017144=IDA, GO:0005783=NAS, GO:0018675=IEA, GO:0070989=IDA, GO:0044281=TAS, GO:0043603=IDA, GO:0043231=TAS, GO:0004497=IDA, GO:0032787=IDA, GO:0008144=IDA, GO:0019627=IDA, GO:0008202=IMP, GO:0005506=IEA, GO:0019373=TAS, GO:0008395=IMP, GO:0009055=IEA, GO:0016098=IDA, GO:0052741=IEA, GO:0042737=IMP, GO:0042738=IDA, GO:0097267=TAS, GO:0005789=TAS, GO:0016491=IDA, GO:0020037=IEA, GO:0055114=IDA} arachidonic acid metabolic process, cellular amide metabolic process, drug catabolic process, drug metabolic process, epoxygenase P450 pathway, exogenous drug catabolic process, monocarboxylic acid metabolic process, monoterpenoid metabolic process, omega-hydroxylase P450 pathway, oxidation-reduction process, oxidative demethylation, small molecule metabolic process, steroid metabolic process, urea metabolic process, xenobiotic metabolic process endoplasmic reticulum, endoplasmic reticulum membrane, intracellular membrane-bounded organelle (R)-limonene 6-monooxygenase activity, (S)-limonene 6-monooxygenase activity, (S)-limonene 7-monooxygenase activity, caffeine oxidase activity, drug binding, electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, steroid hydroxylase activity Human CYP2D6 BHF-UCL UniProtKB {GO:0006805=PMID:19438707, GO:0017144=PMID:18356043, GO:0005783=PMID:19438707, GO:0070989=PMID:19438707, GO:0044281=Reactome:REACT_111217, GO:0005739=PMID:19438707, GO:0004497=PMID:15327587, GO:0009820=PMID:19651758, GO:0009822=PMID:15039299, GO:0008144=PMID:19448135, GO:0016712=GO_REF:0000002, GO:0008202=PMID:18356043, GO:0046483=PMID:15327587, GO:0033076=PMID:19448135, GO:0070330=GO_REF:0000003, GO:0005506=GO_REF:0000002, GO:0009055=GO_REF:0000002, GO:0009804=PMID:19438707, GO:0016098=PMID:16401082, GO:0051100=PMID:19448135, GO:0042737=PMID:15039299, GO:0016491=PMID:16401082, GO:0005789=Reactome:REACT_13478, GO:0090350=PMID:19448135, GO:0055114=PMID:16401082, GO:0020037=PMID:16352597} P10635 Cytochrome P450 2D6 protein 20100204 {GO:0006805=TAS, GO:0017144=IMP, GO:0005783=TAS, GO:0070989=IDA, GO:0044281=TAS, GO:0005739=IDA, GO:0004497=IDA, GO:0009820=IDA, GO:0009822=IDA, GO:0008144=IDA, GO:0016712=IEA, GO:0008202=IMP, GO:0046483=IDA, GO:0033076=IDA, GO:0070330=IEA, GO:0005506=IEA, GO:0009055=IEA, GO:0009804=IDA, GO:0016098=IDA, GO:0051100=IDA, GO:0042737=IDA, GO:0016491=IDA, GO:0005789=TAS, GO:0090350=IDA, GO:0055114=IDA, GO:0020037=IDA} alkaloid catabolic process, alkaloid metabolic process, coumarin metabolic process, drug catabolic process, drug metabolic process, heterocycle metabolic process, isoquinoline alkaloid metabolic process, monoterpenoid metabolic process, negative regulation of binding, negative regulation of cellular organofluorine metabolic process, oxidation-reduction process, oxidative demethylation, small molecule metabolic process, steroid metabolic process, xenobiotic metabolic process endoplasmic reticulum, endoplasmic reticulum membrane, mitochondrion aromatase activity, drug binding, electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen Human CYP2E1 BHF-UCL UniProtKB {GO:0006805=Reactome:REACT_13705, GO:0017144=PMID:18356043, GO:0045471=GO_REF:0000019, GO:0031227=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0005739=GO_REF:0000019, GO:0004497=PMID:19651758, GO:0016712=GO_REF:0000019, GO:0008202=PMID:18356043, GO:0046483=PMID:19651758, GO:0005506=GO_REF:0000002, GO:0042493=GO_REF:0000019, GO:0010193=GO_REF:0000019, GO:0010243=GO_REF:0000019, GO:0009055=GO_REF:0000002, GO:0016098=PMID:16401082, GO:0000139=GO_REF:0000019, GO:0019825=PMID:3233219, GO:0016709=PMID:18818195, GO:0005789=Reactome:REACT_1750, GO:0016491=PMID:16401082, GO:0006641=GO_REF:0000019, GO:0016705=GO_REF:0000002, GO:0019899=PMID:15680923, GO:0020037=PMID:18818195, GO:0055114=PMID:16401082} P05181 Cytochrome P450 2E1 protein 20100205 {GO:0006805=TAS, GO:0017144=IMP, GO:0045471=IEA, GO:0031227=IEA, GO:0044281=TAS, GO:0005739=IEA, GO:0004497=IDA, GO:0016712=IEA, GO:0008202=IMP, GO:0046483=IDA, GO:0005506=IEA, GO:0042493=IEA, GO:0010193=IEA, GO:0010243=IEA, GO:0009055=IEA, GO:0016098=IDA, GO:0000139=IEA, GO:0019825=TAS, GO:0016709=TAS, GO:0005789=TAS, GO:0016491=IDA, GO:0006641=IEA, GO:0016705=IEA, GO:0019899=IPI, GO:0020037=IDA, GO:0055114=IDA} drug metabolic process, heterocycle metabolic process, monoterpenoid metabolic process, oxidation-reduction process, response to drug, response to ethanol, response to organic nitrogen, response to ozone, small molecule metabolic process, steroid metabolic process, triglyceride metabolic process, xenobiotic metabolic process Golgi membrane, endoplasmic reticulum membrane, intrinsic to endoplasmic reticulum membrane, mitochondrion electron carrier activity, enzyme binding, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen, oxygen binding Human UniProtKB:P00167 CYP2J2 BHF-UCL UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0008392=PMID:11901223, GO:0006805=PMID:11901223, GO:0005506=GO_REF:0000002, GO:0070330=GO_REF:0000003, GO:0019373=PMID:11901223, GO:0008016=PMID:8631948, GO:0009055=GO_REF:0000002, GO:0071614=PMID:11901223, GO:0044281=Reactome:REACT_111217, GO:0006690=PMID:8631948, GO:0043651=PMID:11901223, GO:0005789=Reactome:REACT_150442, GO:0008405=PMID:11901223, GO:0008404=PMID:11901223, GO:0020037=GO_REF:0000002} P51589 Cytochrome P450 2J2 protein 20100524 {GO:0019369=TAS, GO:0008392=IDA, GO:0006805=TAS, GO:0005506=IEA, GO:0070330=IEA, GO:0019373=IDA, GO:0008016=TAS, GO:0009055=IEA, GO:0071614=IDA, GO:0044281=TAS, GO:0006690=TAS, GO:0043651=IDA, GO:0005789=TAS, GO:0008405=IDA, GO:0008404=IDA, GO:0020037=IEA} arachidonic acid metabolic process, epoxygenase P450 pathway, icosanoid metabolic process, linoleic acid metabolic process, regulation of heart contraction, small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane arachidonic acid 11,12-epoxygenase activity, arachidonic acid 14,15-epoxygenase activity, arachidonic acid epoxygenase activity, aromatase activity, electron carrier activity, heme binding, iron ion binding, linoleic acid epoxygenase activity Human CYP2S1 Reactome UniProtKB {GO:0004497=GO_REF:0000029, GO:0006805=Reactome:REACT_13705, GO:0070330=GO_REF:0000003, GO:0005506=GO_REF:0000002, GO:0005783=GO_REF:0000029, GO:0005789=Reactome:REACT_13626, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0016705=GO_REF:0000002, GO:0055114=GO_REF:0000029, GO:0020037=GO_REF:0000002} Q96SQ9 Cytochrome P450 2S1 protein 20130301 {GO:0004497=NAS, GO:0006805=TAS, GO:0070330=IEA, GO:0005506=IEA, GO:0005783=NAS, GO:0005789=TAS, GO:0009055=IEA, GO:0044281=TAS, GO:0016705=IEA, GO:0055114=NAS, GO:0020037=IEA} oxidation-reduction process, small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum, endoplasmic reticulum membrane aromatase activity, electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Human CYP2W1 Reactome UniProtKB {GO:0004497=GO_REF:0000037, GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0005789=Reactome:REACT_13592, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0016705=GO_REF:0000002, GO:0020037=GO_REF:0000002} Q8TAV3 Cytochrome P450 2W1 protein 20130301 {GO:0004497=IEA, GO:0006805=TAS, GO:0005506=IEA, GO:0005789=TAS, GO:0009055=IEA, GO:0044281=TAS, GO:0016705=IEA, GO:0020037=IEA} small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Human CYP39A1 Reactome UniProtKB {GO:0006707=GO_REF:0000019, GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0006699=Reactome:REACT_11054, GO:0008396=PMID:10748047, GO:0007586=PMID:10748047, GO:0009055=GO_REF:0000002, GO:0008387=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0033782=GO_REF:0000003, GO:0043231=PMID:10748047, GO:0030573=GO_REF:0000037, GO:0005789=Reactome:REACT_10066, GO:0008206=Reactome:REACT_11040, GO:0020037=GO_REF:0000002} Q9NYL5 24-hydroxycholesterol 7-alpha-hydroxylase protein 20130301 {GO:0006707=IEA, GO:0006805=TAS, GO:0005506=IEA, GO:0006699=TAS, GO:0008396=IDA, GO:0007586=TAS, GO:0009055=IEA, GO:0008387=IEA, GO:0044281=TAS, GO:0033782=IEA, GO:0043231=TAS, GO:0030573=IEA, GO:0005789=TAS, GO:0008206=TAS, GO:0020037=IEA} bile acid biosynthetic process, bile acid catabolic process, bile acid metabolic process, cholesterol catabolic process, digestion, small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane, intracellular membrane-bounded organelle 24-hydroxycholesterol 7alpha-hydroxylase activity, electron carrier activity, heme binding, iron ion binding, oxysterol 7-alpha-hydroxylase activity, steroid 7-alpha-hydroxylase activity Human CYP3A4 BHF-UCL UniProtKB {GO:0006629=PMID:2492107, GO:0034875=PMID:18619574, GO:0006706=PMID:18356043, GO:0006805=Reactome:REACT_13705, GO:0017144=PMID:15327587, GO:0030343=PMID:15546903, GO:0070989=PMID:18619574, GO:0044281=Reactome:REACT_111217, GO:0047638=GO_REF:0000003, GO:0050649=PMID:3259858, GO:0043231=PMID:3460094, GO:0004497=PMID:15327587, GO:0005737=PMID:18446064, GO:0009822=PMID:15039299, GO:0070576=PMID:15546903, GO:0016712=GO_REF:0000002, GO:0005496=PMID:15256616, GO:0008202=PMID:3259858, GO:0046483=PMID:15327587, GO:0009986=PMID:12493773, GO:0005506=PMID:15256616, GO:0042359=PMID:15546903, GO:0008209=PMID:19651758, GO:0008395=PMID:18356043, GO:0033780=GO_REF:0000003, GO:0009055=GO_REF:0000002, GO:0016098=PMID:16401082, GO:0042737=PMID:18356043, GO:0019825=PMID:3460094, GO:0042738=PMID:18619574, GO:0005789=Reactome:REACT_13765, GO:0016491=PMID:16401082, GO:0050591=GO_REF:0000003, GO:0016021=GO_REF:0000037, GO:0016705=GO_REF:0000002, GO:0019899=PMID:15680923, GO:0020037=GO_REF:0000002, GO:0055114=PMID:16401082} P08684 Cytochrome P450 3A4 protein 20100203 {GO:0006629=TAS, GO:0034875=IDA, GO:0006706=IMP, GO:0006805=TAS, GO:0017144=IDA, GO:0030343=IDA, GO:0070989=IDA, GO:0044281=TAS, GO:0047638=IEA, GO:0050649=IMP, GO:0043231=TAS, GO:0004497=IDA, GO:0005737=IDA, GO:0009822=IDA, GO:0070576=IDA, GO:0016712=IEA, GO:0005496=IDA, GO:0008202=IMP, GO:0046483=IDA, GO:0009986=IDA, GO:0005506=IDA, GO:0042359=IC, GO:0008209=TAS, GO:0008395=IMP, GO:0033780=IEA, GO:0009055=IEA, GO:0016098=IDA, GO:0042737=IMP, GO:0019825=TAS, GO:0042738=IDA, GO:0005789=TAS, GO:0016491=IDA, GO:0050591=IEA, GO:0016021=IEA, GO:0016705=IEA, GO:0019899=IPI, GO:0020037=IEA, GO:0055114=IDA} alkaloid catabolic process, androgen metabolic process, drug catabolic process, drug metabolic process, exogenous drug catabolic process, heterocycle metabolic process, lipid metabolic process, monoterpenoid metabolic process, oxidation-reduction process, oxidative demethylation, small molecule metabolic process, steroid catabolic process, steroid metabolic process, vitamin D metabolic process, xenobiotic metabolic process cell surface, cytoplasm, endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle albendazole monooxygenase activity, caffeine oxidase activity, electron carrier activity, enzyme binding, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen, oxygen binding, quinine 3-monooxygenase activity, steroid binding, steroid hydroxylase activity, taurochenodeoxycholate 6alpha-hydroxylase activity, testosterone 6-beta-hydroxylase activity, vitamin D 24-hydroxylase activity, vitamin D3 25-hydroxylase activity Human CYP3A5 BHF-UCL UniProtKB {GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0070330=GO_REF:0000003, GO:0070989=PMID:15039299, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0043231=PMID:2732228, GO:0004497=GO_REF:0000024, GO:0042737=PMID:15039299, GO:0019825=PMID:2732228, GO:0009822=PMID:15039299, GO:0016491=PMID:15039299, GO:0005789=Reactome:REACT_13734, GO:0016712=GO_REF:0000002, GO:0008202=PMID:2732228, GO:0020037=GO_REF:0000002} P20815 Cytochrome P450 3A5 protein 20091105 {GO:0006805=TAS, GO:0005506=IEA, GO:0070330=IEA, GO:0070989=IDA, GO:0009055=IEA, GO:0044281=TAS, GO:0043231=TAS, GO:0004497=ISS, GO:0042737=IDA, GO:0019825=TAS, GO:0009822=IDA, GO:0016491=IDA, GO:0005789=TAS, GO:0016712=IEA, GO:0008202=TAS, GO:0020037=IEA} alkaloid catabolic process, drug catabolic process, oxidative demethylation, small molecule metabolic process, steroid metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane, intracellular membrane-bounded organelle aromatase activity, electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen, oxygen binding Human CYP4A11 GOC UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0001676=PMID:18433732, GO:0006805=Reactome:REACT_13705, GO:0055078=PMID:10660572, GO:0044281=Reactome:REACT_111217, GO:0006691=PMID:9799565, GO:0036101=PMID:9799565, GO:0004497=GO_REF:0000038, GO:0006631=PMID:7679927, GO:0044255=Reactome:REACT_22279, GO:0008392=PMID:9618440, GO:0005506=GO_REF:0000002, GO:0019373=PMID:9618440, GO:0050051=PMID:9799565, GO:0018685=PMID:18433732, GO:0009055=GO_REF:0000002, GO:0052869=GO_REF:0000003, GO:0003091=PMID:10660572, GO:0003095=PMID:10660572, GO:0097267=Reactome:REACT_150134, GO:0032305=PMID:18391101, GO:0005789=Reactome:REACT_150441, GO:0016705=GO_REF:0000002, GO:0055114=PMID:18433732, GO:0020037=GO_REF:0000002} Q02928 Cytochrome P450 4A11 protein 20130413 {GO:0019369=TAS, GO:0001676=IDA, GO:0006805=TAS, GO:0055078=IEP, GO:0044281=TAS, GO:0006691=IDA, GO:0036101=IDA, GO:0004497=IEA, GO:0006631=TAS, GO:0044255=TAS, GO:0008392=IDA, GO:0005506=IEA, GO:0019373=IDA, GO:0050051=IDA, GO:0018685=IDA, GO:0009055=IEA, GO:0052869=IEA, GO:0003091=IEP, GO:0003095=IEP, GO:0097267=TAS, GO:0032305=IMP, GO:0005789=TAS, GO:0016705=IEA, GO:0055114=IDA, GO:0020037=IEA} arachidonic acid metabolic process, cellular lipid metabolic process, epoxygenase P450 pathway, fatty acid metabolic process, leukotriene B4 catabolic process, leukotriene metabolic process, long-chain fatty acid metabolic process, omega-hydroxylase P450 pathway, oxidation-reduction process, positive regulation of icosanoid secretion, pressure natriuresis, renal water homeostasis, small molecule metabolic process, sodium ion homeostasis, xenobiotic metabolic process endoplasmic reticulum membrane alkane 1-monooxygenase activity, arachidonic acid epoxygenase activity, arachidonic acid omega-hydroxylase activity, electron carrier activity, heme binding, iron ion binding, leukotriene-B4 20-monooxygenase activity, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Human CYP4B1 UniProtKB UniProtKB {GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0070330=GO_REF:0000003, GO:0009055=GO_REF:0000002, GO:0018879=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0043231=GO_REF:0000019, GO:0004497=GO_REF:0000038, GO:0019825=PMID:2574990, GO:0042738=GO_REF:0000019, GO:0008144=GO_REF:0000019, GO:0018585=GO_REF:0000019, GO:0018917=GO_REF:0000019, GO:0005789=Reactome:REACT_13615, GO:0016705=GO_REF:0000002, GO:0020037=GO_REF:0000002} Q8IZB0 Pulmonary cytochrome P450 4B1 variant protein 20130413 {GO:0006805=TAS, GO:0005506=IEA, GO:0070330=IEA, GO:0009055=IEA, GO:0018879=IEA, GO:0044281=TAS, GO:0043231=IEA, GO:0004497=IEA, GO:0019825=TAS, GO:0042738=IEA, GO:0008144=IEA, GO:0018585=IEA, GO:0018917=IEA, GO:0005789=TAS, GO:0016705=IEA, GO:0020037=IEA} biphenyl metabolic process, exogenous drug catabolic process, fluorene metabolic process, small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane, intracellular membrane-bounded organelle aromatase activity, drug binding, electron carrier activity, fluorene oxygenase activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, oxygen binding Human UniProtKB-KW:KW-0503 CYP4F11 Reactome UniProtKB {GO:0004497=GO_REF:0000029, GO:0006805=Reactome:REACT_13705, GO:0006954=PMID:10964514, GO:0070330=GO_REF:0000003, GO:0005506=GO_REF:0000002, GO:0005789=Reactome:REACT_13511, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0016705=GO_REF:0000002, GO:0055114=PMID:10964514, GO:0020037=PMID:10964514} Q9HBI6 Cytochrome P450 4F11 protein 20130301 {GO:0004497=NAS, GO:0006805=TAS, GO:0006954=TAS, GO:0070330=IEA, GO:0005506=IEA, GO:0005789=TAS, GO:0009055=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0016705=IEA, GO:0055114=TAS, GO:0020037=TAS} inflammatory response, oxidation-reduction process, small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane, integral to membrane aromatase activity, electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Human CYP4F12 Reactome UniProtKB {GO:0019369=GO_REF:0000024, GO:0000038=GO_REF:0000024, GO:0001676=GO_REF:0000024, GO:0006805=Reactome:REACT_13705, GO:0017144=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0055078=GO_REF:0000024, GO:0043231=GO_REF:0000024, GO:0036101=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0016324=GO_REF:0000024, GO:0042371=GO_REF:0000024, GO:0008392=GO_REF:0000024, GO:0070330=GO_REF:0000003, GO:0005506=GO_REF:0000002, GO:0019373=GO_REF:0000024, GO:0018685=GO_REF:0000024, GO:0050051=GO_REF:0000024, GO:0009055=GO_REF:0000002, GO:0003091=GO_REF:0000024, GO:0003095=GO_REF:0000024, GO:0030195=GO_REF:0000024, GO:0005789=Reactome:REACT_13485, GO:0016021=GO_REF:0000037, GO:0047057=GO_REF:0000024, GO:0042360=GO_REF:0000024, GO:0020037=GO_REF:0000002, GO:0055114=GO_REF:0000024} Q9HCS2 Cytochrome P450 4F12 protein 20130301 {GO:0019369=ISS, GO:0000038=ISS, GO:0001676=ISS, GO:0006805=TAS, GO:0017144=ISS, GO:0044281=TAS, GO:0055078=ISS, GO:0043231=ISS, GO:0036101=ISS, GO:0005737=ISS, GO:0016324=ISS, GO:0042371=ISS, GO:0008392=ISS, GO:0070330=IEA, GO:0005506=IEA, GO:0019373=ISS, GO:0018685=ISS, GO:0050051=ISS, GO:0009055=IEA, GO:0003091=ISS, GO:0003095=ISS, GO:0030195=ISS, GO:0005789=TAS, GO:0016021=IEA, GO:0047057=ISS, GO:0042360=ISS, GO:0020037=IEA, GO:0055114=ISS} arachidonic acid metabolic process, drug metabolic process, epoxygenase P450 pathway, leukotriene B4 catabolic process, long-chain fatty acid metabolic process, negative regulation of blood coagulation, oxidation-reduction process, pressure natriuresis, renal water homeostasis, small molecule metabolic process, sodium ion homeostasis, very long-chain fatty acid metabolic process, vitamin E metabolic process, vitamin K biosynthetic process, xenobiotic metabolic process apical plasma membrane, cytoplasm, endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle alkane 1-monooxygenase activity, arachidonic acid epoxygenase activity, aromatase activity, electron carrier activity, heme binding, iron ion binding, leukotriene-B4 20-monooxygenase activity, vitamin-K-epoxide reductase (warfarin-sensitive) activity Human CYP4F2 BHF-UCL UniProtKB {GO:0005515=PMID:17474147, GO:0019369=Reactome:REACT_147851, GO:0000038=PMID:18433732, GO:0001676=PMID:18433732, GO:0006805=Reactome:REACT_13705, GO:0052871=PMID:20861217, GO:0052872=PMID:20861217, GO:0044281=Reactome:REACT_111217, GO:0055078=PMID:10660572, GO:0006691=Reactome:REACT_150420, GO:0006690=Reactome:REACT_13645, GO:0043231=PMID:20861217, GO:0036101=PMID:8026587, GO:0004497=GO_REF:0000038, GO:0008392=PMID:20861217, GO:0005506=GO_REF:0000002, GO:0019373=PMID:20861217, GO:0018685=PMID:18433732, GO:0050051=PMID:8026587, GO:0009055=GO_REF:0000002, GO:0052869=PMID:10660572, GO:0003091=PMID:10660572, GO:0003095=PMID:10660572, GO:0030195=PMID:19297518, GO:0032304=PMID:18391101, GO:0097267=Reactome:REACT_150134, GO:0032305=PMID:17341693, GO:0005789=Reactome:REACT_150406, GO:0008217=PMID:18391101, GO:0016705=GO_REF:0000002, GO:0042360=PMID:20861217, GO:0055114=PMID:20861217, GO:0020037=GO_REF:0000002} P78329 Leukotriene-B(4) omega-hydroxylase 1 protein 20091102 {GO:0005515=IPI, GO:0019369=TAS, GO:0000038=IDA, GO:0001676=IDA, GO:0006805=TAS, GO:0052871=IDA, GO:0052872=IDA, GO:0044281=TAS, GO:0055078=IEP, GO:0006691=TAS, GO:0006690=TAS, GO:0043231=IDA, GO:0036101=IDA, GO:0004497=IEA, GO:0008392=IDA, GO:0005506=IEA, GO:0019373=IDA, GO:0018685=IDA, GO:0050051=IDA, GO:0009055=IEA, GO:0052869=IDA, GO:0003091=IEP, GO:0003095=IEP, GO:0030195=IMP, GO:0032304=IMP, GO:0097267=TAS, GO:0032305=IMP, GO:0005789=TAS, GO:0008217=IMP, GO:0016705=IEA, GO:0042360=IDA, GO:0055114=IDA, GO:0020037=IEA} arachidonic acid metabolic process, epoxygenase P450 pathway, icosanoid metabolic process, leukotriene B4 catabolic process, leukotriene metabolic process, long-chain fatty acid metabolic process, negative regulation of blood coagulation, negative regulation of icosanoid secretion, omega-hydroxylase P450 pathway, oxidation-reduction process, positive regulation of icosanoid secretion, pressure natriuresis, regulation of blood pressure, renal water homeostasis, small molecule metabolic process, sodium ion homeostasis, very long-chain fatty acid metabolic process, vitamin E metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane, intracellular membrane-bounded organelle alkane 1-monooxygenase activity, alpha-tocopherol omega-hydroxylase activity, arachidonic acid epoxygenase activity, arachidonic acid omega-hydroxylase activity, electron carrier activity, heme binding, iron ion binding, leukotriene-B4 20-monooxygenase activity, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, protein binding, tocotrienol omega-hydroxylase activity Human CYP4F22 UniProtKB UniProtKB {GO:0004497=GO_REF:0000037, GO:0005506=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0009055=GO_REF:0000002, GO:0016705=GO_REF:0000002, GO:0020037=GO_REF:0000002} Q6NT55 Cytochrome P450 4F22 protein 20130413 {GO:0004497=IEA, GO:0005506=IEA, GO:0005789=IEA, GO:0009055=IEA, GO:0016705=IEA, GO:0020037=IEA} endoplasmic reticulum membrane electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Human UniProtKB-SubCell:SL-0097 CYP4F3 Reactome UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0052871=GO_REF:0000003, GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0050051=GO_REF:0000003, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0006691=Reactome:REACT_150420, GO:0006690=Reactome:REACT_13645, GO:0004497=PMID:8486631, GO:0005789=Reactome:REACT_150394, GO:0016705=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0020037=GO_REF:0000002} Q08477 Leukotriene-B(4) omega-hydroxylase 2 protein 20130301 {GO:0019369=TAS, GO:0052871=IEA, GO:0006805=TAS, GO:0005506=IEA, GO:0050051=IEA, GO:0009055=IEA, GO:0044281=TAS, GO:0006691=TAS, GO:0006690=TAS, GO:0004497=TAS, GO:0005789=TAS, GO:0016705=IEA, GO:0016021=IEA, GO:0020037=IEA} arachidonic acid metabolic process, icosanoid metabolic process, leukotriene metabolic process, small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane, integral to membrane alpha-tocopherol omega-hydroxylase activity, electron carrier activity, heme binding, iron ion binding, leukotriene-B4 20-monooxygenase activity, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Human CYP4F8 Reactome UniProtKB {GO:0006805=Reactome:REACT_13705, GO:0006693=PMID:10405341, GO:0070330=GO_REF:0000003, GO:0005506=GO_REF:0000002, GO:0005789=Reactome:REACT_13624, GO:0018685=PMID:10405341, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0006690=Reactome:REACT_13645, GO:0020037=GO_REF:0000002} P98187 Cytochrome P450 4F8 protein 20130301 {GO:0006805=TAS, GO:0006693=TAS, GO:0070330=IEA, GO:0005506=IEA, GO:0005789=TAS, GO:0018685=TAS, GO:0009055=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0006690=TAS, GO:0020037=IEA} icosanoid metabolic process, prostaglandin metabolic process, small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane, integral to membrane alkane 1-monooxygenase activity, aromatase activity, electron carrier activity, heme binding, iron ion binding Human CYP4V2 UniProtKB UniProtKB {GO:0004497=GO_REF:0000037, GO:0010430=PMID:19661213, GO:0005506=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0009055=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0016705=GO_REF:0000002, GO:0007601=GO_REF:0000037, GO:0050896=GO_REF:0000037, GO:0020037=GO_REF:0000002} Q6ZWL3 Cytochrome P450 4V2 protein 20110705 {GO:0004497=IEA, GO:0010430=IDA, GO:0005506=IEA, GO:0005789=IEA, GO:0009055=IEA, GO:0016021=IEA, GO:0016705=IEA, GO:0007601=IEA, GO:0050896=IEA, GO:0020037=IEA} fatty acid omega-oxidation, response to stimulus, visual perception endoplasmic reticulum membrane, integral to membrane electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Human CYP4X1 UniProtKB UniProtKB {GO:0070330=GO_REF:0000003, GO:0005506=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0009055=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0020037=GO_REF:0000002} Q8N118 Cytochrome P450 4X1 protein 20130413 {GO:0070330=IEA, GO:0005506=IEA, GO:0005789=IEA, GO:0009055=IEA, GO:0016021=IEA, GO:0020037=IEA} endoplasmic reticulum membrane, integral to membrane aromatase activity, electron carrier activity, heme binding, iron ion binding Human UniProtKB-SubCell:SL-0097 CYP51A1 Reactome UniProtKB {GO:0006695=Reactome:REACT_9405, GO:0006694=PMID:20149798, GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0009055=GO_REF:0000002, GO:0008398=PMID:20149798, GO:0044281=Reactome:REACT_111217, GO:0033488=GO_REF:0000019, GO:0004497=GO_REF:0000038, GO:0005789=Reactome:REACT_147899, GO:0016705=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0020037=PMID:20149798} Q16850 Lanosterol 14-alpha demethylase protein 20130301 {GO:0006695=TAS, GO:0006694=IDA, GO:0006805=TAS, GO:0005506=IEA, GO:0009055=IEA, GO:0008398=IDA, GO:0044281=TAS, GO:0033488=IEA, GO:0004497=IEA, GO:0005789=TAS, GO:0016705=IEA, GO:0016021=IEA, GO:0020037=IDA} cholesterol biosynthetic process, cholesterol biosynthetic process via 24,25-dihydrolanosterol, small molecule metabolic process, steroid biosynthetic process, xenobiotic metabolic process endoplasmic reticulum membrane, integral to membrane electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, sterol 14-demethylase activity Human CYP7A1 Reactome UniProtKB {GO:0042632=GO_REF:0000024, GO:0006707=GO_REF:0000024, GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0006699=Reactome:REACT_11054, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0043231=GO_REF:0000024, GO:0071397=GO_REF:0000024, GO:0070857=GO_REF:0000024, GO:0005789=Reactome:REACT_115550, GO:0008206=Reactome:REACT_11040, GO:0071333=PMID:19965590, GO:0008123=GO_REF:0000024, GO:0044255=Reactome:REACT_22279, GO:0020037=GO_REF:0000002} P22680 Cholesterol 7-alpha-monooxygenase protein 20130301 {GO:0042632=ISS, GO:0006707=ISS, GO:0006805=TAS, GO:0005506=IEA, GO:0006699=TAS, GO:0009055=IEA, GO:0044281=TAS, GO:0043231=ISS, GO:0071397=ISS, GO:0070857=ISS, GO:0005789=TAS, GO:0008206=TAS, GO:0071333=IDA, GO:0008123=ISS, GO:0044255=TAS, GO:0020037=IEA} bile acid biosynthetic process, bile acid metabolic process, cellular lipid metabolic process, cellular response to cholesterol, cellular response to glucose stimulus, cholesterol catabolic process, cholesterol homeostasis, regulation of bile acid biosynthetic process, small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane, intracellular membrane-bounded organelle cholesterol 7-alpha-monooxygenase activity, electron carrier activity, heme binding, iron ion binding Human CYP7B1 Reactome UniProtKB {GO:0050679=GO_REF:0000019, GO:0008219=GO_REF:0000037, GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0008396=GO_REF:0000019, GO:0006699=Reactome:REACT_11054, GO:0060740=GO_REF:0000019, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0005789=Reactome:REACT_9994, GO:0008206=Reactome:REACT_11040, GO:0033783=GO_REF:0000003, GO:0033147=GO_REF:0000019, GO:0020037=GO_REF:0000002, GO:0008203=GO_REF:0000037} O75881 25-hydroxycholesterol 7-alpha-hydroxylase protein 20130301 {GO:0050679=IEA, GO:0008219=IEA, GO:0006805=TAS, GO:0005506=IEA, GO:0008396=IEA, GO:0006699=TAS, GO:0060740=IEA, GO:0009055=IEA, GO:0044281=TAS, GO:0005789=TAS, GO:0008206=TAS, GO:0033783=IEA, GO:0033147=IEA, GO:0020037=IEA, GO:0008203=IEA} bile acid biosynthetic process, bile acid metabolic process, cell death, cholesterol metabolic process, negative regulation of intracellular estrogen receptor signaling pathway, positive regulation of epithelial cell proliferation, prostate gland epithelium morphogenesis, small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane 25-hydroxycholesterol 7alpha-hydroxylase activity, electron carrier activity, heme binding, iron ion binding, oxysterol 7-alpha-hydroxylase activity Human CYP8B1 Reactome UniProtKB {GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0008397=PMID:10051404, GO:0006699=Reactome:REACT_11054, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0004497=GO_REF:0000002, GO:0033778=GO_REF:0000003, GO:0019825=PMID:10051404, GO:0005789=Reactome:REACT_10071, GO:0008206=Reactome:REACT_11040, GO:0016705=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0020037=GO_REF:0000002} Q9UNU6 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase protein 20130301 {GO:0006805=TAS, GO:0005506=IEA, GO:0008397=TAS, GO:0006699=TAS, GO:0009055=IEA, GO:0044281=TAS, GO:0004497=IEA, GO:0033778=IEA, GO:0019825=TAS, GO:0005789=TAS, GO:0008206=TAS, GO:0016705=IEA, GO:0016021=IEA, GO:0020037=IEA} bile acid biosynthetic process, bile acid metabolic process, small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane, integral to membrane 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity, electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, oxygen binding, sterol 12-alpha-hydroxylase activity Human CYR61 BHF-UCL UniProtKB {GO:0044319=PMID:20675382, GO:0060710=GO_REF:0000019, GO:0060591=GO_REF:0000019, GO:0008283=PMID:9135077, GO:0003181=GO_REF:0000019, GO:0010811=GO_REF:0000019, GO:0003281=GO_REF:0000019, GO:0002041=GO_REF:0000019, GO:0009653=PMID:9135077, GO:0001558=GO_REF:0000002, GO:0030513=PMID:20675382, GO:0006935=GO_REF:0000037, GO:0030198=GO_REF:0000019, GO:0045944=PMID:20675382, GO:0045860=PMID:20675382, GO:0060716=GO_REF:0000019, GO:0033690=PMID:20675382, GO:0070372=PMID:20675382, GO:0008201=GO_REF:0000037, GO:0005520=GO_REF:0000002, GO:0003278=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0030335=PMID:20675382, GO:0043065=GO_REF:0000019, GO:2000304=GO_REF:0000019, GO:0060413=GO_REF:0000019, GO:0072593=GO_REF:0000019, GO:0050840=GO_REF:0000019, GO:0010518=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0001649=GO_REF:0000019, GO:0045669=PMID:20675382, GO:0043280=GO_REF:0000019, GO:0005178=GO_REF:0000019, GO:0001934=PMID:20675382, GO:0061036=GO_REF:0000019} O00622 Protein CYR61 protein 20110414 {GO:0044319=IDA, GO:0060710=IEA, GO:0060591=IEA, GO:0008283=TAS, GO:0003181=IEA, GO:0010811=IEA, GO:0003281=IEA, GO:0002041=IEA, GO:0009653=TAS, GO:0001558=IEA, GO:0030513=IGI, GO:0006935=IEA, GO:0030198=IEA, GO:0045944=IDA, GO:0045860=IDA, GO:0060716=IEA, GO:0033690=IDA, GO:0070372=IDA, GO:0008201=IEA, GO:0005520=IEA, GO:0003278=IEA, GO:0043066=IEA, GO:0030335=IDA, GO:0043065=IEA, GO:2000304=IEA, GO:0060413=IEA, GO:0072593=IEA, GO:0050840=IEA, GO:0010518=IEA, GO:0005576=IEA, GO:0001649=IEA, GO:0045669=IDA, GO:0043280=IEA, GO:0005178=IEA, GO:0001934=IDA, GO:0061036=IEA} anatomical structure morphogenesis, apoptotic process involved in heart morphogenesis, atrial septum morphogenesis, atrioventricular valve morphogenesis, cell proliferation, chemotaxis, chondroblast differentiation, chorio-allantoic fusion, extracellular matrix organization, intussusceptive angiogenesis, labyrinthine layer blood vessel development, negative regulation of apoptotic process, osteoblast differentiation, positive regulation of BMP signaling pathway, positive regulation of apoptotic process, positive regulation of cartilage development, positive regulation of cell migration, positive regulation of cell-substrate adhesion, positive regulation of ceramide biosynthetic process, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of osteoblast differentiation, positive regulation of osteoblast proliferation, positive regulation of phospholipase activity, positive regulation of protein kinase activity, positive regulation of protein phosphorylation, positive regulation of transcription from RNA polymerase II promoter, reactive oxygen species metabolic process, regulation of ERK1 and ERK2 cascade, regulation of cell growth, ventricular septum development, wound healing, spreading of cells extracellular region extracellular matrix binding, heparin binding, insulin-like growth factor binding, integrin binding Human CYTH1 IntAct UniProtKB {GO:0005515=PMID:11867758, GO:0005802=GO_REF:0000033, GO:0090162=GO_REF:0000019, GO:0005086=GO_REF:0000033, GO:0005737=PMID:12606567, GO:0005543=GO_REF:0000002, GO:0005886=PMID:12606567, GO:0032012=GO_REF:0000002, GO:0005923=GO_REF:0000019, GO:0016192=GO_REF:0000033, GO:0030155=PMID:12606567} Q15438 Cytohesin-1 protein 20130415 {GO:0005515=IPI, GO:0005802=IBA, GO:0090162=IEA, GO:0005086=IBA, GO:0005737=IDA, GO:0005543=IEA, GO:0005886=IDA, GO:0032012=IEA, GO:0005923=IEA, GO:0016192=IBA, GO:0030155=IDA} establishment of epithelial cell polarity, regulation of ARF protein signal transduction, regulation of cell adhesion, vesicle-mediated transport cytoplasm, plasma membrane, tight junction, trans-Golgi network ARF guanyl-nucleotide exchange factor activity, phospholipid binding, protein binding Human UniProtKB:O60759 CYTH2 IntAct UniProtKB {GO:0005515=PMID:20946980, GO:0005802=GO_REF:0000033, GO:0005086=GO_REF:0000033, GO:0005737=PMID:17398095, GO:0030036=PMID:9417041, GO:0005543=GO_REF:0000002, GO:0016020=PMID:9417041, GO:0005886=PMID:17398095, GO:0032012=GO_REF:0000002, GO:0016192=GO_REF:0000033, GO:0030155=GO_REF:0000033, GO:0006897=PMID:9417041} Q99418 Cytohesin-2 protein 20130415 {GO:0005515=IPI, GO:0005802=IBA, GO:0005086=IBA, GO:0005737=IDA, GO:0030036=TAS, GO:0005543=IEA, GO:0016020=TAS, GO:0005886=IDA, GO:0032012=IEA, GO:0016192=IBA, GO:0030155=IBA, GO:0006897=TAS} actin cytoskeleton organization, endocytosis, regulation of ARF protein signal transduction, regulation of cell adhesion, vesicle-mediated transport cytoplasm, membrane, plasma membrane, trans-Golgi network ARF guanyl-nucleotide exchange factor activity, phospholipid binding, protein binding Human UniProtKB:P00533 CYTH3 GOC UniProtKB {GO:0090162=GO_REF:0000019, GO:0005802=GO_REF:0000033, GO:0005886=PMID:17398095, GO:0005220=PMID:9742223, GO:0048016=PMID:9742223, GO:0005547=GO_REF:0000019, GO:0001726=GO_REF:0000019, GO:0030155=GO_REF:0000033, GO:0045785=GO_REF:0000019, GO:0005086=GO_REF:0000033, GO:0005545=PMID:9742223, GO:0005737=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0016020=PMID:9742223, GO:0032012=GO_REF:0000002, GO:0016192=GO_REF:0000033} O43739 Cytohesin-3 protein 20130413 {GO:0090162=IEA, GO:0005802=IBA, GO:0005886=IDA, GO:0005220=TAS, GO:0048016=TAS, GO:0005547=IEA, GO:0001726=IEA, GO:0030155=IBA, GO:0045785=IEA, GO:0005086=IBA, GO:0005545=TAS, GO:0005737=IEA, GO:0005543=IEA, GO:0016020=TAS, GO:0032012=IEA, GO:0016192=IBA} establishment of epithelial cell polarity, inositol phosphate-mediated signaling, positive regulation of cell adhesion, regulation of ARF protein signal transduction, regulation of cell adhesion, vesicle-mediated transport cytoplasm, membrane, plasma membrane, ruffle, trans-Golgi network 1-phosphatidylinositol binding, ARF guanyl-nucleotide exchange factor activity, inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity, phosphatidylinositol-3,4,5-trisphosphate binding, phospholipid binding Human CYTH4 UniProtKB UniProtKB {GO:0005802=GO_REF:0000033, GO:0005086=GO_REF:0000033, GO:0005543=GO_REF:0000002, GO:0005886=PMID:17398095, GO:0032012=GO_REF:0000002, GO:0016192=GO_REF:0000033, GO:0030155=GO_REF:0000033} Q9UIA0 Cytohesin-4 protein 20101220 {GO:0005802=IBA, GO:0005086=IBA, GO:0005543=IEA, GO:0005886=IDA, GO:0032012=IEA, GO:0016192=IBA, GO:0030155=IBA} regulation of ARF protein signal transduction, regulation of cell adhesion, vesicle-mediated transport plasma membrane, trans-Golgi network ARF guanyl-nucleotide exchange factor activity, phospholipid binding Human CYTIP HPA UniProtKB {GO:0005515=PMID:11867758, GO:0005737=GO_REF:0000052, GO:0030155=PMID:12606567, GO:0005938=PMID:12606567, GO:0005769=GO_REF:0000039} O60759 Cytohesin-interacting protein protein 20080818 {GO:0005515=IPI, GO:0005737=IDA, GO:0030155=IDA, GO:0005938=IDA, GO:0005769=IEA} regulation of cell adhesion cell cortex, cytoplasm, early endosome protein binding Human D2HGDH Reactome UniProtKB {GO:0008762=GO_REF:0000002, GO:0050660=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0010043=PMID:15070399, GO:0010042=PMID:15070399, GO:0051990=PMID:15070399, GO:0005739=PMID:15070399, GO:0051592=PMID:15070399, GO:0005759=Reactome:REACT_25270, GO:0006103=Reactome:REACT_25367, GO:0032026=PMID:15070399, GO:0032025=PMID:15070399, GO:0044267=PMID:15070399} Q8N465 D-2-hydroxyglutarate dehydrogenase, mitochondrial protein 20130301 {GO:0008762=IEA, GO:0050660=IEA, GO:0044281=TAS, GO:0003824=IEA, GO:0010043=ISS, GO:0010042=ISS, GO:0051990=ISS, GO:0005739=ISS, GO:0051592=ISS, GO:0005759=TAS, GO:0006103=TAS, GO:0032026=ISS, GO:0032025=ISS, GO:0044267=ISS} 2-oxoglutarate metabolic process, cellular protein metabolic process, response to calcium ion, response to cobalt ion, response to magnesium ion, response to manganese ion, response to zinc ion, small molecule metabolic process mitochondrial matrix, mitochondrion (R)-2-hydroxyglutarate dehydrogenase activity, UDP-N-acetylmuramate dehydrogenase activity, catalytic activity, flavin adenine dinucleotide binding Human DAAM1 HPA UniProtKB {GO:0005515=PMID:18218625, GO:0005737=GO_REF:0000052, GO:0030036=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0017048=GO_REF:0000002, GO:0003779=GO_REF:0000037, GO:0042802=PMID:18218625} Q9Y4D1 Disheveled-associated activator of morphogenesis 1 protein 20101115 {GO:0005515=IPI, GO:0005737=IDA, GO:0030036=IEA, GO:0005886=IDA, GO:0017048=IEA, GO:0003779=IEA, GO:0042802=IPI} actin cytoskeleton organization cytoplasm, plasma membrane Rho GTPase binding, actin binding, identical protein binding, protein binding Human DAAM2 InterPro UniProtKB {GO:0030036=GO_REF:0000002, GO:0017048=GO_REF:0000002, GO:0003779=GO_REF:0000002} Q86T65 Disheveled-associated activator of morphogenesis 2 protein 20130413 {GO:0030036=IEA, GO:0017048=IEA, GO:0003779=IEA} actin cytoskeleton organization Rho GTPase binding, actin binding Human InterPro:IPR003104|InterPro:IPR010473 DAB1 ENSEMBL UniProtKB {GO:0048471=GO_REF:0000019, GO:0007264=GO_REF:0000019, GO:0021942=GO_REF:0000019, GO:0021517=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0045860=GO_REF:0000019, GO:0007628=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0051645=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0014069=GO_REF:0000019, GO:0045177=GO_REF:0000019, GO:0021813=GO_REF:0000019, GO:0016358=GO_REF:0000019, GO:0046426=GO_REF:0000019, GO:0021589=GO_REF:0000019, GO:0005903=GO_REF:0000019, GO:0048712=GO_REF:0000019, GO:0007162=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0045666=GO_REF:0000019, GO:0007494=GO_REF:0000019, GO:0050771=GO_REF:0000019, GO:0001764=GO_REF:0000019, GO:0043548=GO_REF:0000019} O75553 Disabled homolog 1 protein 20130413 {GO:0048471=IEA, GO:0007264=IEA, GO:0021942=IEA, GO:0021517=IEA, GO:0005829=IEA, GO:0045860=IEA, GO:0007628=IEA, GO:0043025=IEA, GO:0051645=IEA, GO:0042493=IEA, GO:0014069=IEA, GO:0045177=IEA, GO:0021813=IEA, GO:0016358=IEA, GO:0046426=IEA, GO:0021589=IEA, GO:0005903=IEA, GO:0048712=IEA, GO:0007162=IEA, GO:0016020=IEA, GO:0045666=IEA, GO:0007494=IEA, GO:0050771=IEA, GO:0001764=IEA, GO:0043548=IEA} Golgi localization, adult walking behavior, cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration, cerebellum structural organization, dendrite development, midgut development, negative regulation of JAK-STAT cascade, negative regulation of astrocyte differentiation, negative regulation of axonogenesis, negative regulation of cell adhesion, neuron migration, positive regulation of neuron differentiation, positive regulation of protein kinase activity, radial glia guided migration of Purkinje cell, response to drug, small GTPase mediated signal transduction, ventral spinal cord development apical part of cell, brush border, cytosol, membrane, neuronal cell body, perinuclear region of cytoplasm, postsynaptic density phosphatidylinositol 3-kinase binding Human Ensembl:ENSMUSP00000102443 DAB2 BHF-UCL UniProtKB {GO:0005515=PMID:12805222, GO:0006907=GO_REF:0000019, GO:2000096=PMID:12805222, GO:0071560=GO_REF:0000019, GO:0046332=PMID:11387212, GO:0015031=GO_REF:0000037, GO:0005765=Reactome:REACT_10083, GO:0070022=PMID:11387212, GO:1900026=GO_REF:0000019, GO:0030099=GO_REF:0000019, GO:0016055=GO_REF:0000037, GO:2001046=GO_REF:0000019, GO:0030335=GO_REF:0000019, GO:0038024=PMID:16984970, GO:0005546=GO_REF:0000019, GO:0060766=PMID:16267015, GO:0001701=GO_REF:0000019, GO:0060391=PMID:11387212, GO:0005178=GO_REF:0000019, GO:0032968=GO_REF:0000019, GO:0045893=PMID:12805222, GO:0045892=PMID:12805222, GO:0016044=Reactome:REACT_11123, GO:0032091=PMID:12805222, GO:2000370=PMID:16984970, GO:0035615=PMID:16984970, GO:0030132=GO_REF:0000019, GO:0005886=Reactome:REACT_9971, GO:0008283=PMID:9620555, GO:0035612=GO_REF:0000019, GO:0010718=PMID:15734730, GO:0032436=PMID:12805222, GO:0005634=GO_REF:0000019, GO:0045807=PMID:21995445, GO:0016324=GO_REF:0000019, GO:0001921=GO_REF:0000019, GO:0090090=PMID:12805222, GO:0030511=PMID:11387212, GO:0007588=GO_REF:0000019, GO:0043066=PMID:15734730, GO:2000643=PMID:21995445, GO:0010862=PMID:11387212, GO:0006915=GO_REF:0000037, GO:0007257=GO_REF:0000019, GO:0008022=PMID:15837803, GO:0030665=GO_REF:0000039, GO:0005905=PMID:12857860, GO:0000904=GO_REF:0000019, GO:0007492=GO_REF:0000019, GO:0001934=PMID:12805222, GO:0048268=GO_REF:0000019} P98082 Disabled homolog 2 protein 20110110 {GO:0005515=IPI, GO:0006907=IEA, GO:2000096=IMP, GO:0071560=IEA, GO:0046332=IDA, GO:0015031=IEA, GO:0005765=TAS, GO:0070022=IDA, GO:1900026=IEA, GO:0030099=IEA, GO:0016055=IEA, GO:2001046=IEA, GO:0030335=IEA, GO:0038024=IMP, GO:0005546=IEA, GO:0060766=IMP, GO:0001701=IEA, GO:0060391=IDA, GO:0005178=IEA, GO:0032968=IEA, GO:0045893=IMP, GO:0045892=IMP, GO:0016044=TAS, GO:0032091=IMP, GO:2000370=IMP, GO:0035615=IMP, GO:0030132=IEA, GO:0005886=TAS, GO:0008283=TAS, GO:0035612=IEA, GO:0010718=IDA, GO:0032436=IMP, GO:0005634=IEA, GO:0045807=IMP, GO:0016324=IEA, GO:0001921=IEA, GO:0090090=IMP, GO:0030511=IDA, GO:0007588=IEA, GO:0043066=IDA, GO:2000643=IMP, GO:0010862=IDA, GO:0006915=IEA, GO:0007257=IEA, GO:0008022=IPI, GO:0030665=IEA, GO:0005905=IDA, GO:0000904=IEA, GO:0007492=IEA, GO:0001934=IMP, GO:0048268=IEA} Wnt receptor signaling pathway, activation of JUN kinase activity, apoptotic process, cell morphogenesis involved in differentiation, cell proliferation, cellular membrane organization, cellular response to transforming growth factor beta stimulus, clathrin coat assembly, endoderm development, excretion, in utero embryonic development, myeloid cell differentiation, negative regulation of androgen receptor signaling pathway, negative regulation of apoptotic process, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of protein binding, negative regulation of transcription, DNA-dependent, pinocytosis, positive regulation of SMAD protein import into nucleus, positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway, positive regulation of cell migration, positive regulation of clathrin-mediated endocytosis, positive regulation of early endosome to late endosome transport, positive regulation of endocytosis, positive regulation of epithelial to mesenchymal transition, positive regulation of integrin-mediated signaling pathway, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of protein phosphorylation, positive regulation of receptor recycling, positive regulation of substrate adhesion-dependent cell spreading, positive regulation of transcription elongation from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of transforming growth factor beta receptor signaling pathway, protein transport apical plasma membrane, clathrin coat of coated pit, clathrin-coated vesicle membrane, coated pit, lysosomal membrane, nucleus, plasma membrane, transforming growth factor beta receptor homodimeric complex AP-2 adaptor complex binding, SMAD binding, cargo receptor activity, clathrin adaptor activity, integrin binding, phosphatidylinositol-4,5-bisphosphate binding, protein C-terminus binding, protein binding Human DAB2IP BHF-UCL UniProtKB {GO:0005515=PMID:19903888, GO:0030308=GO_REF:0000019, GO:0090129=GO_REF:0000024, GO:0050680=PMID:20154697, GO:0046330=PMID:19903888, GO:0070273=PMID:19948740, GO:0032403=PMID:19903888, GO:0042803=PMID:12813029, GO:0071158=PMID:19903888, GO:0046580=PMID:20154697, GO:0032312=GO_REF:0000024, GO:0043553=PMID:19903888, GO:1900744=GO_REF:0000024, GO:0071356=PMID:15310755, GO:0043025=GO_REF:0000024, GO:0070373=PMID:19903888, GO:0044257=PMID:17389591, GO:0034261=PMID:20154697, GO:0043122=GO_REF:0000024, GO:0034260=GO_REF:0000024, GO:0043124=PMID:15310755, GO:0019901=PMID:20080667, GO:0031235=GO_REF:0000033, GO:0042059=PMID:11812785, GO:0031434=PMID:17389591, GO:0031435=PMID:12813029, GO:0036324=GO_REF:0000024, GO:0005123=PMID:15310755, GO:0000122=PMID:15310755, GO:0014067=PMID:19903888, GO:0032266=PMID:19948740, GO:0010596=PMID:19033661, GO:0032320=GO_REF:0000033, GO:0070059=PMID:18281285, GO:0010976=GO_REF:0000024, GO:0071347=PMID:19948740, GO:0043184=PMID:19033661, GO:0045892=PMID:20080667, GO:0043548=PMID:19033661, GO:0030948=PMID:19033661, GO:0035662=PMID:19948740, GO:0030424=GO_REF:0000024, GO:0034144=PMID:19948740, GO:0045732=GO_REF:0000024, GO:0017124=PMID:19903888, GO:0035924=PMID:19033661, GO:0008285=PMID:19903888, GO:0071902=PMID:20080667, GO:0005886=PMID:15310755, GO:0071901=PMID:20154697, GO:2001235=PMID:19903888, GO:0048147=GO_REF:0000024, GO:0030139=PMID:19948740, GO:0010719=PMID:20080667, GO:0035414=GO_REF:0000024, GO:0071889=PMID:17389591, GO:0005737=GO_REF:0000052, GO:0000185=PMID:19903888, GO:0005543=GO_REF:0000002, GO:0043407=PMID:12813029, GO:0045944=PMID:15310755, GO:0043507=PMID:15310755, GO:0019900=PMID:17389591, GO:0051721=PMID:20080667, GO:0090090=PMID:20080667, GO:1900006=GO_REF:0000024, GO:0035591=PMID:20080667, GO:0043065=PMID:12813029, GO:0044301=GO_REF:0000024, GO:2001224=GO_REF:0000024, GO:0007252=GO_REF:0000024, GO:0035148=PMID:19033661, GO:0044300=GO_REF:0000024, GO:1990032=GO_REF:0000024, GO:0021814=GO_REF:0000024, GO:0032088=PMID:20154697, GO:0007257=PMID:12813029, GO:0070317=PMID:19903888, GO:0021819=GO_REF:0000024, GO:1900747=GO_REF:0000024, GO:0032809=GO_REF:0000024, GO:0036312=PMID:19903888, GO:0005099=GO_REF:0000024, GO:2000599=PMID:19903888, GO:1901800=PMID:20080667, GO:0047485=GO_REF:0000019, GO:0071222=PMID:19948740, GO:0071364=PMID:11812785, GO:0048812=GO_REF:0000024, GO:0016525=PMID:19033661, GO:0043254=PMID:19948740, GO:0001933=PMID:20080667, GO:0043410=PMID:19903888, GO:0010633=PMID:20080667} Q5VWQ8 Disabled homolog 2-interacting protein protein 20101119 {GO:0005515=IPI, GO:0030308=IEA, GO:0090129=ISS, GO:0050680=IMP, GO:0046330=IDA, GO:0070273=IDA, GO:0032403=IDA, GO:0042803=IPI, GO:0071158=IDA, GO:0046580=IC, GO:0032312=ISS, GO:0043553=IDA, GO:1900744=ISS, GO:0071356=IDA, GO:0043025=ISS, GO:0070373=IDA, GO:0044257=IDA, GO:0034261=IMP, GO:0043122=ISS, GO:0034260=ISS, GO:0043124=IDA, GO:0019901=IPI, GO:0031235=IBA, GO:0042059=ISS, GO:0031434=IPI, GO:0031435=IPI, GO:0036324=ISS, GO:0005123=IPI, GO:0000122=IDA, GO:0014067=IDA, GO:0032266=IDA, GO:0010596=IMP, GO:0032320=IBA, GO:0070059=ISS, GO:0010976=ISS, GO:0071347=IDA, GO:0043184=IPI, GO:0045892=IMP, GO:0043548=IDA, GO:0030948=IMP, GO:0035662=IDA, GO:0030424=ISS, GO:0034144=IDA, GO:0045732=ISS, GO:0017124=IDA, GO:0035924=IDA, GO:0008285=IDA, GO:0071902=IMP, GO:0005886=IDA, GO:0071901=IMP, GO:2001235=IDA, GO:0048147=ISS, GO:0030139=IDA, GO:0010719=IMP, GO:0035414=ISS, GO:0071889=IDA, GO:0005737=IDA, GO:0000185=IDA, GO:0005543=IEA, GO:0043407=IDA, GO:0045944=IDA, GO:0043507=IDA, GO:0019900=IPI, GO:0051721=IDA, GO:0090090=IMP, GO:1900006=ISS, GO:0035591=IDA, GO:0043065=IDA, GO:0044301=ISS, GO:2001224=ISS, GO:0007252=ISS, GO:0035148=IMP, GO:0044300=ISS, GO:1990032=ISS, GO:0021814=ISS, GO:0032088=IMP, GO:0007257=IDA, GO:0070317=IDA, GO:0021819=ISS, GO:1900747=ISS, GO:0032809=ISS, GO:0036312=IDA, GO:0005099=ISS, GO:2000599=IDA, GO:1901800=IMP, GO:0047485=IEA, GO:0071222=IDA, GO:0071364=ISS, GO:0048812=ISS, GO:0016525=IDA, GO:0043254=IDA, GO:0001933=IMP, GO:0043410=IDA, GO:0010633=TAS} I-kappaB phosphorylation, activation of JUN kinase activity, activation of MAPKKK activity, cell motility involved in cerebral cortex radial glia guided migration, cellular protein catabolic process, cellular response to epidermal growth factor stimulus, cellular response to interleukin-1, cellular response to lipopolysaccharide, cellular response to tumor necrosis factor, cellular response to vascular endothelial growth factor stimulus, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, layer formation in cerebral cortex, negative regulation of ERK1 and ERK2 cascade, negative regulation of G0 to G1 transition, negative regulation of GTPase activity, negative regulation of I-kappaB kinase/NF-kappaB cascade, negative regulation of MAP kinase activity, negative regulation of NF-kappaB transcription factor activity, negative regulation of Ras GTPase activity, negative regulation of Ras protein signal transduction, negative regulation of angiogenesis, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of catenin import into nucleus, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of cyclin catabolic process, negative regulation of endothelial cell migration, negative regulation of epidermal growth factor receptor signaling pathway, negative regulation of epithelial cell migration, negative regulation of epithelial cell proliferation, negative regulation of epithelial to mesenchymal transition, negative regulation of fibroblast proliferation, negative regulation of phosphatidylinositol 3-kinase activity, negative regulation of phosphatidylinositol 3-kinase cascade, negative regulation of protein phosphorylation, negative regulation of protein serine/threonine kinase activity, negative regulation of toll-like receptor 4 signaling pathway, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, negative regulation of vascular endothelial growth factor receptor signaling pathway, negative regulation of vascular endothelial growth factor signaling pathway, neuron projection morphogenesis, positive regulation of JNK cascade, positive regulation of JUN kinase activity, positive regulation of MAPK cascade, positive regulation of Ras GTPase activity, positive regulation of apoptotic process, positive regulation of apoptotic signaling pathway, positive regulation of cell cycle arrest, positive regulation of dendrite development, positive regulation of neuron migration, positive regulation of neuron projection development, positive regulation of proteasomal protein catabolic process, positive regulation of protein catabolic process, positive regulation of protein serine/threonine kinase activity, positive regulation of synapse maturation, positive regulation of transcription from RNA polymerase II promoter, regulation of ARF GTPase activity, regulation of I-kappaB kinase/NF-kappaB cascade, regulation of p38MAPK cascade, regulation of protein complex assembly, tube formation, vascular endothelial growth factor receptor-2 signaling pathway axon, cerebellar mossy fiber, climbing fiber, cytoplasm, endocytic vesicle, intrinsic to internal side of plasma membrane, neuronal cell body, neuronal cell body membrane, parallel fiber, plasma membrane 14-3-3 protein binding, Ras GTPase activator activity, SH3 domain binding, Toll-like receptor 4 binding, death receptor binding, kinase binding, mitogen-activated protein kinase kinase binding, mitogen-activated protein kinase kinase kinase binding, phosphatidylinositol 3-kinase binding, phosphatidylinositol 3-kinase regulatory subunit binding, phosphatidylinositol-3-phosphate binding, phosphatidylinositol-4-phosphate binding, phospholipid binding, protein N-terminus binding, protein binding, protein complex binding, protein homodimerization activity, protein kinase binding, protein phosphatase 2A binding, signaling adaptor activity, vascular endothelial growth factor receptor 2 binding Human DACH1 HPA UniProtKB {GO:0046545=GO_REF:0000019, GO:0005515=PMID:20956529, GO:0005667=GO_REF:0000019, GO:0030336=PMID:20956529, GO:0007585=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0048147=GO_REF:0000019, GO:0060244=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0001078=PMID:20956529, GO:0005737=GO_REF:0000019, GO:0010944=PMID:20956529, GO:0001967=GO_REF:0000019, GO:0000166=GO_REF:0000002, GO:0001075=GO_REF:0000019} Q9UI36 Dachshund homolog 1 protein 20101115 {GO:0046545=IEA, GO:0005515=IPI, GO:0005667=IEA, GO:0030336=IDA, GO:0007585=IEA, GO:0008283=IEA, GO:0005730=IDA, GO:0048147=IEA, GO:0060244=IEA, GO:0005634=IDA, GO:0003677=IEA, GO:0001078=IDA, GO:0005737=IEA, GO:0010944=IMP, GO:0001967=IEA, GO:0000166=IEA, GO:0001075=IEA} cell proliferation, development of primary female sexual characteristics, negative regulation of cell migration, negative regulation of cell proliferation involved in contact inhibition, negative regulation of fibroblast proliferation, negative regulation of transcription by competitive promoter binding, respiratory gaseous exchange, suckling behavior cytoplasm, nucleolus, nucleus, transcription factor complex DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly, nucleotide binding, protein binding Human DACH2 HPA UniProtKB {GO:0046545=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96NX9 Dachshund homolog 2 protein 20101115 {GO:0046545=IEA, GO:0006355=IEA, GO:0000166=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA} development of primary female sexual characteristics, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus, nucleus DNA binding, nucleotide binding NOT Human DACT1 IntAct UniProtKB {GO:0005515=PMID:22470507, GO:0045732=PMID:16446366, GO:0030054=GO_REF:0000037, GO:0008013=PMID:22470507, GO:0030178=PMID:16446366, GO:0030877=PMID:22470507, GO:0045202=GO_REF:0000039, GO:2000095=GO_REF:0000024, GO:0030177=PMID:21262972, GO:0005634=GO_REF:0000039, GO:0035413=PMID:15580286, GO:0035412=PMID:18936100, GO:1900107=PMID:17197390, GO:0005737=PMID:16446366, GO:0046329=PMID:17197390, GO:0031647=PMID:21262972, GO:0005080=GO_REF:0000024, GO:0016055=GO_REF:0000037, GO:0051018=PMID:21262972, GO:0090090=GO_REF:0000019, GO:0070097=GO_REF:0000024, GO:2000134=PMID:18936100, GO:0000122=PMID:18936100, GO:0001702=GO_REF:0000019, GO:0048813=GO_REF:0000019, GO:0050808=GO_REF:0000019, GO:0048619=GO_REF:0000024, GO:0045600=GO_REF:0000019} Q9NYF0 Dapper homolog 1 protein 20130415 {GO:0005515=IPI, GO:0045732=IDA, GO:0030054=IEA, GO:0008013=IDA, GO:0030178=IGI, GO:0030877=IDA, GO:0045202=IEA, GO:2000095=ISS, GO:0030177=IDA, GO:0005634=IEA, GO:0035413=IMP, GO:0035412=IMP, GO:1900107=IDA, GO:0005737=IDA, GO:0046329=IDA, GO:0031647=IDA, GO:0005080=ISS, GO:0016055=IEA, GO:0051018=IDA, GO:0090090=IEA, GO:0070097=ISS, GO:2000134=IDA, GO:0000122=IDA, GO:0001702=IEA, GO:0048813=IEA, GO:0050808=IEA, GO:0048619=ISS, GO:0045600=IEA} Wnt receptor signaling pathway, dendrite morphogenesis, embryonic hindgut morphogenesis, gastrulation with mouth forming second, negative regulation of G1/S transition of mitotic cell cycle, negative regulation of JNK cascade, negative regulation of Wnt receptor signaling pathway, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, positive regulation of Wnt receptor signaling pathway, positive regulation of catenin import into nucleus, positive regulation of fat cell differentiation, positive regulation of protein catabolic process, regulation of Wnt receptor signaling pathway, planar cell polarity pathway, regulation of catenin import into nucleus, regulation of nodal signaling pathway, regulation of protein stability, synapse organization beta-catenin destruction complex, cell junction, cytoplasm, nucleus, synapse beta-catenin binding, delta-catenin binding, protein binding, protein kinase A binding, protein kinase C binding Human UniProtKB:P49841 DACT2 UniProtKB UniProtKB {GO:0003382=GO_REF:0000024, GO:1900108=GO_REF:0000024, GO:0005739=GO_REF:0000019, GO:0007162=GO_REF:0000024, GO:0070097=GO_REF:0000024, GO:0008013=GO_REF:0000024, GO:0072061=GO_REF:0000024, GO:0005080=GO_REF:0000024, GO:0043588=GO_REF:0000024, GO:0051018=GO_REF:0000024, GO:0008134=GO_REF:0000024} Q5SW24 Dapper homolog 2 protein 20120730 {GO:0003382=ISS, GO:1900108=ISS, GO:0005739=IEA, GO:0007162=ISS, GO:0070097=ISS, GO:0008013=ISS, GO:0072061=ISS, GO:0005080=ISS, GO:0043588=ISS, GO:0051018=ISS, GO:0008134=ISS} epithelial cell morphogenesis, inner medullary collecting duct development, negative regulation of cell adhesion, negative regulation of nodal signaling pathway, skin development mitochondrion beta-catenin binding, delta-catenin binding, protein kinase A binding, protein kinase C binding, transcription factor binding Human UniProtKB:Q7TN08 DACT3 UniProtKB UniProtKB {GO:0030308=PMID:18538736, GO:0070097=GO_REF:0000024, GO:0005080=GO_REF:0000024, GO:0030178=PMID:18538736, GO:0051018=GO_REF:0000024, GO:0016055=GO_REF:0000037, GO:0035414=PMID:18538736} Q96B18 Dapper homolog 3 protein 20120730 {GO:0030308=IDA, GO:0070097=ISS, GO:0005080=ISS, GO:0030178=IDA, GO:0051018=ISS, GO:0016055=IEA, GO:0035414=IDA} Wnt receptor signaling pathway, negative regulation of Wnt receptor signaling pathway, negative regulation of catenin import into nucleus, negative regulation of cell growth delta-catenin binding, protein kinase A binding, protein kinase C binding Human UniProtKB:Q0PHV7 DAD1 Reactome UniProtKB {GO:0004576=GO_REF:0000024, GO:0043066=GO_REF:0000019, GO:0007584=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0001824=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0004579=PMID:15835887, GO:0005789=Reactome:REACT_22208, GO:0006486=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0008250=PMID:15835887, GO:0044267=Reactome:REACT_17015, GO:0018279=Reactome:REACT_22426, GO:0043687=Reactome:REACT_22161} P61803 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 protein 20130213 {GO:0004576=ISS, GO:0043066=IEA, GO:0007584=IEA, GO:0042493=IEA, GO:0001824=IEA, GO:0006915=IEA, GO:0004579=IC, GO:0005789=TAS, GO:0006486=ISS, GO:0016021=IEA, GO:0008250=TAS, GO:0044267=TAS, GO:0018279=TAS, GO:0043687=TAS} apoptotic process, blastocyst development, cellular protein metabolic process, negative regulation of apoptotic process, post-translational protein modification, protein N-linked glycosylation via asparagine, protein glycosylation, response to drug, response to nutrient endoplasmic reticulum membrane, integral to membrane, oligosaccharyltransferase complex dolichyl-diphosphooligosaccharide-protein glycotransferase activity, oligosaccharyl transferase activity Human DAG1 IntAct UniProtKB {GO:0051898=PMID:19587235, GO:0005515=PMID:19109891, GO:0034453=PMID:18341635, GO:0005886=PMID:18764929, GO:0022011=GO_REF:0000019, GO:0030175=PMID:18341635, GO:0006607=PMID:20512930, GO:0005615=PMID:18201566, GO:0043409=PMID:19587235, GO:0005737=PMID:18764929, GO:0016010=PMID:17993586, GO:0015631=PMID:18341635, GO:0016011=GO_REF:0000019, GO:0045211=GO_REF:0000039, GO:0021682=GO_REF:0000019, GO:0006509=PMID:19946898, GO:0008307=PMID:18691338, GO:0005856=GO_REF:0000039, GO:0042169=PMID:11724572, GO:0007016=PMID:18341635, GO:0030336=PMID:19587235, GO:0002011=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0003779=PMID:18341635, GO:0030027=PMID:18341635, GO:0005604=PMID:19348877, GO:0042383=GO_REF:0000039, GO:0060441=GO_REF:0000019, GO:0033268=GO_REF:0000019, GO:0051393=PMID:18341635, GO:0019048=PMID:16254364, GO:0043237=GO_REF:0000024, GO:0017166=PMID:18341635, GO:0009279=GO_REF:0000019, GO:0045121=GO_REF:0000019, GO:0005654=PMID:18764929, GO:0016021=PMID:17628813, GO:0005925=PMID:18341635, GO:0070938=PMID:18341635, GO:0060445=GO_REF:0000019} Q14118 Dystroglycan protein 20130415 {GO:0051898=IMP, GO:0005515=IPI, GO:0034453=IMP, GO:0005886=IDA, GO:0022011=IEA, GO:0030175=IDA, GO:0006607=IDA, GO:0005615=IDA, GO:0043409=IMP, GO:0005737=IDA, GO:0016010=IDA, GO:0015631=IDA, GO:0016011=IEA, GO:0045211=IEA, GO:0021682=IEA, GO:0006509=IDA, GO:0008307=IMP, GO:0005856=IEA, GO:0042169=IDA, GO:0007016=IMP, GO:0030336=IMP, GO:0002011=IEA, GO:0005509=IEA, GO:0003779=IDA, GO:0030027=IDA, GO:0005604=IDA, GO:0042383=IEA, GO:0060441=IEA, GO:0033268=IEA, GO:0051393=IDA, GO:0019048=IDA, GO:0043237=ISS, GO:0017166=IPI, GO:0009279=IEA, GO:0045121=IEA, GO:0005654=IDA, GO:0016021=IDA, GO:0005925=IDA, GO:0070938=IDA, GO:0060445=IEA} NLS-bearing substrate import into nucleus, branching involved in salivary gland morphogenesis, cytoskeletal anchoring at plasma membrane, epithelial tube branching involved in lung morphogenesis, membrane protein ectodomain proteolysis, microtubule anchoring, morphogenesis of an epithelial sheet, myelination in peripheral nervous system, negative regulation of MAPK cascade, negative regulation of cell migration, negative regulation of protein kinase B signaling cascade, nerve maturation, virus-host interaction basement membrane, cell outer membrane, contractile ring, cytoplasm, cytoskeleton, dystroglycan complex, dystrophin-associated glycoprotein complex, extracellular space, filopodium, focal adhesion, integral to membrane, lamellipodium, membrane raft, node of Ranvier, nucleoplasm, plasma membrane, postsynaptic membrane, sarcolemma SH2 domain binding, actin binding, alpha-actinin binding, calcium ion binding, laminin-1 binding, protein binding, structural constituent of muscle, tubulin binding, vinculin binding Human UniProtKB:Q3T1J5 DAGLB Reactome UniProtKB {GO:0016042=GO_REF:0000037, GO:0006629=GO_REF:0000002, GO:0004806=GO_REF:0000002, GO:0005886=Reactome:REACT_19135, GO:0007596=Reactome:REACT_604, GO:0030168=Reactome:REACT_798, GO:0016021=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q8NCG7 Sn1-specific diacylglycerol lipase beta protein 20130301 {GO:0016042=IEA, GO:0006629=IEA, GO:0004806=IEA, GO:0005886=TAS, GO:0007596=TAS, GO:0030168=TAS, GO:0016021=IEA, GO:0046872=IEA} blood coagulation, lipid catabolic process, lipid metabolic process, platelet activation integral to membrane, plasma membrane metal ion binding, triglyceride lipase activity Human DAK Reactome UniProtKB {GO:0050354=GO_REF:0000003, GO:0004371=GO_REF:0000003, GO:0045087=Reactome:REACT_6802, GO:0005524=GO_REF:0000037, GO:0006071=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_25160, GO:0034012=GO_REF:0000003} Q3LXA3 Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing) protein 20100802 {GO:0050354=IEA, GO:0004371=IEA, GO:0045087=TAS, GO:0005524=IEA, GO:0006071=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0034012=IEA} glycerol metabolic process, innate immune response cytosol ATP binding, FAD-AMP lyase (cyclizing) activity, glycerone kinase activity, metal ion binding, triokinase activity Human DALRD3 InterPro UniProtKB {GO:0006420=GO_REF:0000002, GO:0004814=GO_REF:0000002, GO:0005524=GO_REF:0000002} Q5D0E6 DALR anticodon-binding domain-containing protein 3 protein 20130413 {GO:0006420=IEA, GO:0004814=IEA, GO:0005524=IEA} arginyl-tRNA aminoacylation ATP binding, arginine-tRNA ligase activity Human InterPro:IPR008909 DAND5 BHF-UCL UniProtKB {GO:1900108=GO_REF:0000024, GO:0030514=GO_REF:0000024, GO:0016015=GO_REF:0000024, GO:0003140=GO_REF:0000024, GO:0003283=GO_REF:0000024, GO:0005576=PMID:15466485, GO:0003281=GO_REF:0000024, GO:0038101=GO_REF:0000024, GO:0061371=GO_REF:0000024, GO:0030512=GO_REF:0000024} Q8N907 DAN domain family member 5 protein 20120322 {GO:1900108=ISS, GO:0030514=ISS, GO:0016015=ISS, GO:0003140=ISS, GO:0003283=ISS, GO:0005576=NAS, GO:0003281=ISS, GO:0038101=ISS, GO:0061371=ISS, GO:0030512=ISS} atrial septum development, determination of heart left/right asymmetry, determination of left/right asymmetry in lateral mesoderm, negative regulation of BMP signaling pathway, negative regulation of nodal signaling pathway, negative regulation of transforming growth factor beta receptor signaling pathway, sequestering of nodal from receptor via nodal binding, ventricular septum development extracellular region morphogen activity Human UniProtKB:Q76LW6 DAO Reactome UniProtKB {GO:0005515=PMID:21679769, GO:0070178=PMID:21679769, GO:0048037=PMID:20603179, GO:0005782=Reactome:REACT_17049, GO:0005102=PMID:20178365, GO:0036088=PMID:18544534, GO:0005741=PMID:21679769, GO:0044281=Reactome:REACT_111217, GO:0005829=PMID:21679769, GO:0042416=PMID:17303072, GO:0034641=Reactome:REACT_13, GO:0071949=PMID:19309736, GO:0016641=GO_REF:0000002, GO:0046983=PMID:19309736, GO:0006562=PMID:16616139, GO:0046487=Reactome:REACT_16925, GO:0003884=Reactome:REACT_17049, GO:0055130=PMID:20603179, GO:0005778=PMID:21679769, GO:0006551=GO_REF:0000019, GO:0005777=PMID:18544534} P14920 D-amino-acid oxidase protein 20130213 {GO:0005515=IPI, GO:0070178=IDA, GO:0048037=IDA, GO:0005782=TAS, GO:0005102=IPI, GO:0036088=IDA, GO:0005741=IDA, GO:0044281=TAS, GO:0005829=IDA, GO:0042416=IDA, GO:0034641=TAS, GO:0071949=IDA, GO:0016641=IEA, GO:0046983=IDA, GO:0006562=IDA, GO:0046487=TAS, GO:0003884=TAS, GO:0055130=IDA, GO:0005778=IDA, GO:0006551=IEA, GO:0005777=IDA} D-alanine catabolic process, D-serine catabolic process, D-serine metabolic process, cellular nitrogen compound metabolic process, dopamine biosynthetic process, glyoxylate metabolic process, leucine metabolic process, proline catabolic process, small molecule metabolic process cytosol, mitochondrial outer membrane, peroxisomal matrix, peroxisomal membrane, peroxisome D-amino-acid oxidase activity, FAD binding, cofactor binding, oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor, protein binding, protein dimerization activity, receptor binding Human DAOA UniProtKB UniProtKB {GO:0005739=PMID:21679769, GO:0048471=PMID:21679769, GO:0005794=PMID:12364586, GO:0019899=PMID:21679769} P59103 D-amino acid oxidase activator protein 20120530 {GO:0005739=IDA, GO:0048471=IDA, GO:0005794=IDA, GO:0019899=IPI} Golgi apparatus, mitochondrion, perinuclear region of cytoplasm enzyme binding Human UniProtKB:P14920 DAP MGI UniProtKB {GO:0070513=PMID:1087798, GO:0006919=PMID:1087798, GO:0010507=PMID:20537536, GO:0006914=GO_REF:0000037, GO:0006915=PMID:7828849, GO:0032088=PMID:1087798, GO:0045892=PMID:1087798, GO:0097190=PMID:1087798, GO:0034198=PMID:20537536} P51397 Death-associated protein 1 protein 20120105 {GO:0070513=IPI, GO:0006919=IMP, GO:0010507=IMP, GO:0006914=IEA, GO:0006915=IGI, GO:0032088=IMP, GO:0045892=IMP, GO:0097190=IMP, GO:0034198=IDA} activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, apoptotic signaling pathway, autophagy, cellular response to amino acid starvation, negative regulation of NF-kappaB transcription factor activity, negative regulation of autophagy, negative regulation of transcription, DNA-dependent death domain binding Human UniProtKB:P01579 DAP3 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005515=PMID:19103604, GO:0008637=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0015935=GO_REF:0000002, GO:0005761=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0097190=PMID:7499268} P51398 28S ribosomal protein S29, mitochondrial protein 20101115 {GO:0005739=IDA, GO:0005515=IPI, GO:0008637=IEA, GO:0005730=IDA, GO:0015935=IEA, GO:0005761=IEA, GO:0005634=IDA, GO:0097190=TAS} apoptotic mitochondrial changes, apoptotic signaling pathway mitochondrial ribosome, mitochondrion, nucleolus, nucleus, small ribosomal subunit protein binding Human DAPK1 InterPro UniProtKB {GO:0017148=PMID:18995835, GO:0005515=PMID:19712061, GO:0005516=PMID:10629061, GO:0043066=GO_REF:0000019, GO:0006915=Reactome:REACT_578, GO:2000310=GO_REF:0000024, GO:0042981=Reactome:REACT_13648, GO:0006917=PMID:10629061, GO:0015629=PMID:10629061, GO:0005524=GO_REF:0000002, GO:0097190=PMID:7828849, GO:0007243=PMID:10629061, GO:0042802=PMID:19712061, GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0004672=PMID:7828849, GO:0046777=PMID:16756490, GO:0071346=PMID:18995835, GO:0004674=GO_REF:0000002, GO:0010506=PMID:16756490, GO:0006468=PMID:16756490} Q5T8F1 Death-associated protein kinase 1 protein 20130413 {GO:0017148=IDA, GO:0005515=IPI, GO:0005516=IDA, GO:0043066=IEA, GO:0006915=TAS, GO:2000310=ISS, GO:0042981=TAS, GO:0006917=IMP, GO:0015629=IDA, GO:0005524=IEA, GO:0097190=IMP, GO:0007243=IDA, GO:0042802=IPI, GO:0007165=IEA, GO:0005737=IEA, GO:0004672=IDA, GO:0046777=TAS, GO:0071346=IDA, GO:0004674=IEA, GO:0010506=TAS, GO:0006468=TAS} apoptotic process, apoptotic signaling pathway, cellular response to interferon-gamma, induction of apoptosis, intracellular protein kinase cascade, negative regulation of apoptotic process, negative regulation of translation, protein autophosphorylation, protein phosphorylation, regulation of N-methyl-D-aspartate selective glutamate receptor activity, regulation of apoptotic process, regulation of autophagy, signal transduction actin cytoskeleton, cytoplasm ATP binding, calmodulin binding, identical protein binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human InterPro:IPR000488 DAPK2 IntAct UniProtKB {GO:0005516=PMID:10376525, GO:0034423=GO_REF:0000039, GO:0043276=PMID:18957423, GO:0042981=PMID:16756490, GO:0031410=GO_REF:0000037, GO:0006917=PMID:10376525, GO:0005524=PMID:10376525, GO:0007243=PMID:10376525, GO:0042802=PMID:11230133, GO:0005737=PMID:10376525, GO:0004672=GO_REF:0000002, GO:0046777=PMID:16756490, GO:0004674=PMID:16756490, GO:0010506=PMID:16756490, GO:0006468=PMID:10376525, GO:0004683=PMID:10629061} Q9UIK4 Death-associated protein kinase 2 protein 20130415 {GO:0005516=IDA, GO:0034423=IEA, GO:0043276=IMP, GO:0042981=TAS, GO:0031410=IEA, GO:0006917=IMP, GO:0005524=IDA, GO:0007243=IDA, GO:0042802=IPI, GO:0005737=IDA, GO:0004672=IEA, GO:0046777=TAS, GO:0004674=TAS, GO:0010506=TAS, GO:0006468=IDA, GO:0004683=TAS} anoikis, induction of apoptosis, intracellular protein kinase cascade, protein autophosphorylation, protein phosphorylation, regulation of apoptotic process, regulation of autophagy autophagic vacuole lumen, cytoplasm, cytoplasmic vesicle ATP binding, calmodulin binding, calmodulin-dependent protein kinase activity, identical protein binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB:Q9UIK4 DAPK3 UniProtKB UniProtKB {GO:0017148=PMID:18995835, GO:0090263=PMID:21454679, GO:2000145=DOI:10.1002/sita.200600112, GO:0005634=GO_REF:0000024, GO:0006940=DOI:10.1002/sita.200600112, GO:0007243=PMID:10356987, GO:0042803=PMID:18239682, GO:0043522=PMID:10580117, GO:2000249=DOI:10.1002/sita.200600112, GO:0000910=DOI:10.1002/sita.200600112, GO:0005737=GO_REF:0000039, GO:0046777=PMID:16756490, GO:0030182=GO_REF:0000019, GO:2001241=GO_REF:0000019, GO:0006355=DOI:10.1002/sita.200600112, GO:0007088=DOI:10.1002/sita.200600112, GO:0005815=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0042981=PMID:16756490, GO:0006917=PMID:10580117, GO:0005524=PMID:10356987, GO:0006351=GO_REF:0000037, GO:0004672=GO_REF:0000002, GO:0071346=PMID:18995835, GO:0004674=PMID:16756490, GO:0016605=GO_REF:0000039, GO:0010506=PMID:16756490, GO:0006468=PMID:10356987, GO:0000775=GO_REF:0000039, GO:0016568=GO_REF:0000037} O43293 Death-associated protein kinase 3 protein 20121203 {GO:0017148=IDA, GO:0090263=IMP, GO:2000145=TAS, GO:0005634=ISS, GO:0006940=TAS, GO:0007243=IDA, GO:0042803=IDA, GO:0043522=IPI, GO:2000249=TAS, GO:0000910=TAS, GO:0005737=IEA, GO:0046777=TAS, GO:0030182=IEA, GO:2001241=IEA, GO:0006355=TAS, GO:0007088=TAS, GO:0005815=IEA, GO:0006915=IEA, GO:0042981=TAS, GO:0006917=IDA, GO:0005524=IDA, GO:0006351=IEA, GO:0004672=IEA, GO:0071346=IDA, GO:0004674=TAS, GO:0016605=IEA, GO:0010506=TAS, GO:0006468=IDA, GO:0000775=IEA, GO:0016568=IEA} apoptotic process, cellular response to interferon-gamma, chromatin modification, cytokinesis, induction of apoptosis, intracellular protein kinase cascade, negative regulation of translation, neuron differentiation, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of extrinsic apoptotic signaling pathway in absence of ligand, protein autophosphorylation, protein phosphorylation, regulation of actin cytoskeleton reorganization, regulation of apoptotic process, regulation of autophagy, regulation of cell motility, regulation of mitosis, regulation of smooth muscle contraction, regulation of transcription, DNA-dependent, transcription, DNA-dependent PML body, chromosome, centromeric region, cytoplasm, microtubule organizing center, nucleus ATP binding, leucine zipper domain binding, protein homodimerization activity, protein kinase activity, protein serine/threonine kinase activity Human DAPP1 GOC UniProtKB {GO:0007165=PMID:10432293, GO:0006470=PMID:10432293, GO:0005543=PMID:10432293, GO:0005886=Reactome:REACT_118781, GO:0043325=PMID:17823121, GO:0005547=PMID:11001876, GO:0035335=GO_REF:0000029, GO:0004725=GO_REF:0000029, GO:0005829=Reactome:REACT_118566} Q9UN19 Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide protein 20130413 {GO:0007165=TAS, GO:0006470=NAS, GO:0005543=NAS, GO:0005886=TAS, GO:0043325=IDA, GO:0005547=IDA, GO:0035335=NAS, GO:0004725=NAS, GO:0005829=TAS} peptidyl-tyrosine dephosphorylation, protein dephosphorylation, signal transduction cytosol, plasma membrane phosphatidylinositol-3,4,5-trisphosphate binding, phosphatidylinositol-3,4-bisphosphate binding, phospholipid binding, protein tyrosine phosphatase activity Human DARC ENSEMBL UniProtKB {GO:0070098=GO_REF:0000029, GO:0006954=GO_REF:0000019, GO:0005886=Reactome:REACT_14786, GO:0004950=GO_REF:0000029, GO:0032642=GO_REF:0000019, GO:0004872=PMID:7689250, GO:0006952=PMID:10570183, GO:0016021=GO_REF:0000002, GO:0019957=PMID:7517217, GO:0019956=GO_REF:0000002, GO:0004888=PMID:9058825} Q5JY94 Duffy antigen/chemokine receptor protein 20130413 {GO:0070098=NAS, GO:0006954=IEA, GO:0005886=TAS, GO:0004950=NAS, GO:0032642=IEA, GO:0004872=TAS, GO:0006952=NAS, GO:0016021=IEA, GO:0019957=IPI, GO:0019956=IEA, GO:0004888=TAS} chemokine-mediated signaling pathway, defense response, inflammatory response, regulation of chemokine production integral to membrane, plasma membrane C-C chemokine binding, chemokine binding, chemokine receptor activity, receptor activity, transmembrane signaling receptor activity Human Ensembl:ENSMUSP00000045134 DARS HPA UniProtKB {GO:0005515=PMID:19380743, GO:0010467=Reactome:REACT_71, GO:0006422=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0006461=PMID:8449960, GO:0004046=PMID:8449960, GO:0004815=GO_REF:0000003, GO:0003676=GO_REF:0000002, GO:0006412=PMID:8449960, GO:0005524=GO_REF:0000037, GO:0006418=Reactome:REACT_15482, GO:0005829=Reactome:REACT_15516} P14868 Aspartate--tRNA ligase, cytoplasmic protein 20111111 {GO:0005515=IPI, GO:0010467=TAS, GO:0006422=IEA, GO:0005737=IDA, GO:0006461=TAS, GO:0004046=TAS, GO:0004815=IEA, GO:0003676=IEA, GO:0006412=TAS, GO:0005524=IEA, GO:0006418=TAS, GO:0005829=TAS} aspartyl-tRNA aminoacylation, gene expression, protein complex assembly, tRNA aminoacylation for protein translation, translation cytoplasm, cytosol ATP binding, aminoacylase activity, aspartate-tRNA ligase activity, nucleic acid binding, protein binding Human DARS2 UniProtKB UniProtKB {GO:0005515=PMID:15779907, GO:0010467=Reactome:REACT_71, GO:0000049=PMID:15779907, GO:0050560=PMID:17384640, GO:0005634=GO_REF:0000052, GO:0004815=Reactome:REACT_15437, GO:0070145=PMID:15779907, GO:0005524=GO_REF:0000002, GO:0004812=GO_REF:0000038, GO:0042803=PMID:15779907, GO:0006418=GO_REF:0000002, GO:0005739=PMID:15779907, GO:0005737=GO_REF:0000002, GO:0005759=Reactome:REACT_15437, GO:0043039=PMID:17384640} Q9H9M6 cDNA FLJ12651 fis, clone NT2RM4002062, moderately similar to ASPARTYL-TRNA SYNTHETASE (EC 6.1.1.12) protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0000049=TAS, GO:0050560=IDA, GO:0005634=IDA, GO:0004815=TAS, GO:0070145=IC, GO:0005524=IEA, GO:0004812=IEA, GO:0042803=IPI, GO:0006418=IEA, GO:0005739=TAS, GO:0005737=IEA, GO:0005759=TAS, GO:0043039=IDA} gene expression, mitochondrial asparaginyl-tRNA aminoacylation, tRNA aminoacylation, tRNA aminoacylation for protein translation cytoplasm, mitochondrial matrix, mitochondrion, nucleus ATP binding, aminoacyl-tRNA ligase activity, aspartate-tRNA ligase activity, aspartate-tRNA(Asn) ligase activity, protein binding, protein homodimerization activity, tRNA binding Human UniProtKB-KW:KW-0030 DAXX BHF-UCL UniProtKB {GO:0005515=PMID:21988832, GO:0000792=GO_REF:0000019, GO:0008625=PMID:9215629, GO:0005634=PMID:15878163, GO:0050681=PMID:15572661, GO:0005829=GO_REF:0000024, GO:0002039=PMID:16845383, GO:0005737=PMID:15572661, GO:0031072=PMID:15572661, GO:0031396=PMID:18566590, GO:0031625=PMID:16845383, GO:0006355=PMID:15878163, GO:0000281=GO_REF:0000019, GO:0005730=GO_REF:0000039, GO:0006915=PMID:15572661, GO:0006917=GO_REF:0000024, GO:0007257=PMID:9215629, GO:0006351=GO_REF:0000037, GO:0047485=PMID:18566590, GO:0019048=GO_REF:0000037, GO:0016605=PMID:15247905, GO:0005057=PMID:9215629, GO:0019899=PMID:16845383, GO:0045892=PMID:15572661, GO:0030521=PMID:15572661, GO:0000775=GO_REF:0000039} Q9UER7 Death domain-associated protein 6 protein 20081024 {GO:0005515=IPI, GO:0000792=IEA, GO:0008625=TAS, GO:0005634=IDA, GO:0050681=IPI, GO:0005829=ISS, GO:0002039=IPI, GO:0005737=TAS, GO:0031072=TAS, GO:0031396=IDA, GO:0031625=IPI, GO:0006355=IDA, GO:0000281=IEA, GO:0005730=IEA, GO:0006915=TAS, GO:0006917=ISS, GO:0007257=TAS, GO:0006351=IEA, GO:0047485=IPI, GO:0019048=IEA, GO:0016605=TAS, GO:0005057=TAS, GO:0019899=IPI, GO:0045892=IDA, GO:0030521=IDA, GO:0000775=IEA} activation of JUN kinase activity, androgen receptor signaling pathway, apoptotic process, cytokinesis after mitosis, extrinsic apoptotic signaling pathway via death domain receptors, induction of apoptosis, negative regulation of transcription, DNA-dependent, regulation of protein ubiquitination, regulation of transcription, DNA-dependent, transcription, DNA-dependent, virus-host interaction PML body, chromosome, centromeric region, cytoplasm, cytosol, heterochromatin, nucleolus, nucleus androgen receptor binding, enzyme binding, heat shock protein binding, p53 binding, protein N-terminus binding, protein binding, receptor signaling protein activity, ubiquitin protein ligase binding Human DAZ1 IntAct UniProtKB {GO:0005515=PMID:12511597, GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0045948=PMID:16001084, GO:0008494=PMID:16001084, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0030154=GO_REF:0000037} Q9NQZ3 Deleted in azoospermia protein 1 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0045948=IDA, GO:0008494=IDA, GO:0005634=IEA, GO:0007275=IEA, GO:0007283=IEA, GO:0003676=IEA, GO:0030154=IEA} cell differentiation, multicellular organismal development, positive regulation of translational initiation, spermatogenesis cytoplasm, nucleus RNA binding, nucleic acid binding, nucleotide binding, protein binding, translation activator activity Human UniProtKB:Q8TB72 DAZ2 PINC UniProtKB {GO:0007338=PMID:8896558, GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0030154=GO_REF:0000037} Q13117 Deleted in azoospermia protein 2 protein 20030904 {GO:0007338=TAS, GO:0005737=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0007275=IEA, GO:0007283=IEA, GO:0003676=IEA, GO:0030154=IEA} cell differentiation, multicellular organismal development, single fertilization, spermatogenesis cytoplasm, nucleus RNA binding, nucleic acid binding, nucleotide binding Human DAZ3 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0030154=GO_REF:0000037} Q9NR90 Deleted in azoospermia protein 3 protein 20130413 {GO:0005737=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0007275=IEA, GO:0007283=IEA, GO:0003676=IEA, GO:0030154=IEA} cell differentiation, multicellular organismal development, spermatogenesis cytoplasm, nucleus RNA binding, nucleic acid binding, nucleotide binding Human UniProtKB-SubCell:SL-0086 DAZ4 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0030154=GO_REF:0000037} Q86SG3 Deleted in azoospermia protein 4 protein 20130413 {GO:0005737=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0007275=IEA, GO:0007283=IEA, GO:0003676=IEA, GO:0030154=IEA} cell differentiation, multicellular organismal development, spermatogenesis cytoplasm, nucleus RNA binding, nucleic acid binding, nucleotide binding Human UniProtKB-SubCell:SL-0086 DAZAP1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0030154=GO_REF:0000037} Q96EP5 DAZ-associated protein 1 protein 20080818 {GO:0005737=IDA, GO:0000166=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0007275=IEA, GO:0007283=IEA, GO:0003676=IEA, GO:0030154=IEA} cell differentiation, multicellular organismal development, spermatogenesis cytoplasm, nucleolus, nucleus RNA binding, nucleic acid binding, nucleotide binding Human DAZAP2 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0005737=GO_REF:0000039, GO:0050699=PMID:11342538, GO:0005634=GO_REF:0000039} Q15038 DAZ-associated protein 2 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0050699=IPI, GO:0005634=IEA} cytoplasm, nucleus WW domain binding, protein binding Human UniProtKB:Q9UNA4 DAZL PINC UniProtKB {GO:0005515=PMID:16001084, GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0045948=PMID:16001084, GO:0008494=PMID:16001084, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0007281=PMID:9288969} Q92904 Deleted in azoospermia-like protein 20050308 {GO:0005515=IPI, GO:0005737=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0045948=IDA, GO:0008494=IDA, GO:0005634=IEA, GO:0007275=IEA, GO:0007283=IEA, GO:0003676=IEA, GO:0007281=TAS} germ cell development, multicellular organismal development, positive regulation of translational initiation, spermatogenesis cytoplasm, nucleus RNA binding, nucleic acid binding, nucleotide binding, protein binding, translation activator activity Human DBC1 HPA UniProtKB {GO:0005515=PMID:12442002, GO:0008219=PMID:14712213, GO:0005737=PMID:11420708, GO:0015630=GO_REF:0000052, GO:0007050=GO_REF:0000037, GO:0045786=PMID:11420708} O60477 Deleted in bladder cancer protein 1 protein 20110516 {GO:0005515=IPI, GO:0008219=IDA, GO:0005737=IDA, GO:0015630=IDA, GO:0007050=IEA, GO:0045786=IDA} cell cycle arrest, cell death, negative regulation of cell cycle cytoplasm, microtubule cytoskeleton protein binding Human DBF4 GOC UniProtKB {GO:0006260=Reactome:REACT_6769, GO:0000082=Reactome:REACT_1783, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_6750, GO:0008270=GO_REF:0000002, GO:0043085=PMID:10373557, GO:0000278=Reactome:REACT_152, GO:0008047=PMID:10373557, GO:0003676=GO_REF:0000002} Q9UBU7 Protein DBF4 homolog A protein 20130413 {GO:0006260=TAS, GO:0000082=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0008270=IEA, GO:0043085=TAS, GO:0000278=TAS, GO:0008047=TAS, GO:0003676=IEA} DNA replication, G1/S transition of mitotic cell cycle, cell cycle checkpoint, mitotic cell cycle, positive regulation of catalytic activity nucleoplasm enzyme activator activity, nucleic acid binding, zinc ion binding Human DBF4B HPA UniProtKB {GO:0007049=GO_REF:0000037, GO:0016235=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0043231=GO_REF:0000052} Q8NFT6 Protein DBF4 homolog B protein 20120912 {GO:0007049=IEA, GO:0016235=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003676=IEA, GO:0043231=IDA} cell cycle aggresome, intracellular membrane-bounded organelle, nucleus nucleic acid binding, zinc ion binding Human DBH InterPro UniProtKB {GO:0007268=PMID:2880016, GO:0044281=Reactome:REACT_111217, GO:0003824=PMID:3443096, GO:0001816=GO_REF:0000019, GO:0050900=GO_REF:0000019, GO:0034641=Reactome:REACT_13, GO:0004500=GO_REF:0000002, GO:0042596=GO_REF:0000019, GO:0005737=PMID:3443096, GO:0045907=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0002443=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0007613=GO_REF:0000019, GO:0030658=GO_REF:0000039, GO:0034466=GO_REF:0000039, GO:0042711=GO_REF:0000019, GO:0031418=GO_REF:0000037, GO:0005507=GO_REF:0000002, GO:0005576=PMID:14718574, GO:0042981=GO_REF:0000019, GO:0042593=GO_REF:0000019, GO:0001975=GO_REF:0000019, GO:0016020=PMID:3443096, GO:0042584=GO_REF:0000039, GO:0006584=GO_REF:0000002, GO:0001974=GO_REF:0000019, GO:0048149=GO_REF:0000019, GO:0042583=GO_REF:0000029, GO:0008542=GO_REF:0000019, GO:0042421=GO_REF:0000041, GO:0042420=GO_REF:0000019, GO:0048265=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0042423=Reactome:REACT_15551, GO:0034774=Reactome:REACT_15372, GO:0042309=GO_REF:0000019} Q5T382 Dopamine beta-hydroxylase protein 20130413 {GO:0007268=TAS, GO:0044281=TAS, GO:0003824=TAS, GO:0001816=IEA, GO:0050900=IEA, GO:0034641=TAS, GO:0004500=IEA, GO:0042596=IEA, GO:0005737=TAS, GO:0045907=IEA, GO:0042127=IEA, GO:0002443=IEA, GO:0007626=IEA, GO:0007613=IEA, GO:0030658=IEA, GO:0034466=IEA, GO:0042711=IEA, GO:0031418=IEA, GO:0005507=IEA, GO:0005576=NAS, GO:0042981=IEA, GO:0042593=IEA, GO:0001975=IEA, GO:0016020=TAS, GO:0042584=IEA, GO:0006584=IEA, GO:0001974=IEA, GO:0048149=IEA, GO:0042583=NAS, GO:0008542=IEA, GO:0042421=IEA, GO:0042420=IEA, GO:0048265=IEA, GO:0016021=IEA, GO:0042423=TAS, GO:0034774=TAS, GO:0042309=IEA} behavioral response to ethanol, blood vessel remodeling, catecholamine biosynthetic process, catecholamine metabolic process, cellular nitrogen compound metabolic process, cytokine production, dopamine catabolic process, fear response, glucose homeostasis, homoiothermy, leukocyte mediated immunity, leukocyte migration, locomotory behavior, maternal behavior, memory, norepinephrine biosynthetic process, positive regulation of vasoconstriction, regulation of apoptotic process, regulation of cell proliferation, response to amphetamine, response to pain, small molecule metabolic process, synaptic transmission, visual learning chromaffin granule, chromaffin granule lumen, chromaffin granule membrane, cytoplasm, extracellular region, integral to membrane, membrane, secretory granule lumen, transport vesicle membrane L-ascorbic acid binding, catalytic activity, copper ion binding, dopamine beta-monooxygenase activity Human InterPro:IPR000945 DBI PINC UniProtKB {GO:0005739=GO_REF:0000019, GO:0005794=GO_REF:0000039, GO:0005783=GO_REF:0000039, GO:0006810=GO_REF:0000037, GO:0006641=GO_REF:0000019, GO:0043588=GO_REF:0000019, GO:0030156=PMID:3020548, GO:0001942=GO_REF:0000019, GO:0000062=GO_REF:0000002, GO:0008289=GO_REF:0000037} P07108 Acyl-CoA-binding protein protein 20040116 {GO:0005739=IEA, GO:0005794=IEA, GO:0005783=IEA, GO:0006810=IEA, GO:0006641=IEA, GO:0043588=IEA, GO:0030156=TAS, GO:0001942=IEA, GO:0000062=IEA, GO:0008289=IEA} hair follicle development, skin development, transport, triglyceride metabolic process Golgi apparatus, endoplasmic reticulum, mitochondrion benzodiazepine receptor binding, fatty-acyl-CoA binding, lipid binding Human DBN1 UniProtKB UniProtKB {GO:0042641=PMID:12761245, GO:0005886=GO_REF:0000019, GO:0048699=GO_REF:0000019, GO:0003779=PMID:12761245, GO:0015629=GO_REF:0000024, GO:0030425=PMID:12009525, GO:0005622=GO_REF:0000002, GO:0061351=GO_REF:0000019, GO:0005737=PMID:12009525, GO:0048168=PMID:12009525, GO:0050773=PMID:12009525, GO:0005921=GO_REF:0000019, GO:0007015=GO_REF:0000024, GO:0010643=GO_REF:0000019, GO:0032507=GO_REF:0000019, GO:0005522=GO_REF:0000024, GO:0010644=GO_REF:0000019} Q16643 Drebrin protein 20041006 {GO:0042641=NAS, GO:0005886=IEA, GO:0048699=IEA, GO:0003779=NAS, GO:0015629=ISS, GO:0030425=NAS, GO:0005622=IEA, GO:0061351=IEA, GO:0005737=NAS, GO:0048168=NAS, GO:0050773=NAS, GO:0005921=IEA, GO:0007015=ISS, GO:0010643=IEA, GO:0032507=IEA, GO:0005522=ISS, GO:0010644=IEA} actin filament organization, cell communication by chemical coupling, cell communication by electrical coupling, generation of neurons, maintenance of protein location in cell, neural precursor cell proliferation, regulation of dendrite development, regulation of neuronal synaptic plasticity actin cytoskeleton, actomyosin, cytoplasm, dendrite, gap junction, intracellular, plasma membrane actin binding, profilin binding Human UniProtKB:Q07266 DBNDD2 UniProtKB UniProtKB {GO:0005515=PMID:16618118, GO:0005737=GO_REF:0000002, GO:0006469=PMID:16618118} Q9BQY9 Dysbindin domain-containing protein 2 protein 20100127 {GO:0005515=IPI, GO:0005737=IEA, GO:0006469=IDA} negative regulation of protein kinase activity cytoplasm protein binding Human DBNL IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0071800=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0002102=GO_REF:0000024, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_12025, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000024, GO:0051015=GO_REF:0000024, GO:0005938=GO_REF:0000024, GO:0019904=GO_REF:0000019, GO:0014069=GO_REF:0000019, GO:0006915=Reactome:REACT_578, GO:0003779=GO_REF:0000024, GO:0007257=PMID:10567356, GO:0008022=GO_REF:0000019, GO:0001726=GO_REF:0000024, GO:0007416=GO_REF:0000024, GO:0030027=GO_REF:0000024, GO:0006897=GO_REF:0000037, GO:0030665=GO_REF:0000039, GO:0016601=GO_REF:0000024, GO:0000139=GO_REF:0000039, GO:0048812=GO_REF:0000024, GO:0008047=PMID:10567356} Q9UJU6 Drebrin-like protein protein 20130415 {GO:0005515=IPI, GO:0071800=ISS, GO:0030054=IEA, GO:0005886=IEA, GO:0002102=ISS, GO:0006921=TAS, GO:0005829=TAS, GO:0005622=IEA, GO:0005737=ISS, GO:0051015=ISS, GO:0005938=ISS, GO:0019904=IEA, GO:0014069=IEA, GO:0006915=TAS, GO:0003779=ISS, GO:0007257=TAS, GO:0008022=IEA, GO:0001726=ISS, GO:0007416=ISS, GO:0030027=ISS, GO:0006897=IEA, GO:0030665=IEA, GO:0016601=ISS, GO:0000139=IEA, GO:0048812=ISS, GO:0008047=TAS} Rac protein signal transduction, activation of JUN kinase activity, apoptotic process, cellular component disassembly involved in execution phase of apoptosis, endocytosis, neuron projection morphogenesis, podosome assembly, synapse assembly Golgi membrane, cell cortex, cell junction, clathrin-coated vesicle membrane, cytoplasm, cytosol, intracellular, lamellipodium, plasma membrane, podosome, postsynaptic density, ruffle actin binding, actin filament binding, enzyme activator activity, protein C-terminus binding, protein binding, protein domain specific binding Human UniProtKB:Q9H788 DBP BHF-UCL UniProtKB {GO:0001889=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0001077=PMID:20093779, GO:0000977=PMID:20093779, GO:0003700=GO_REF:0000002, GO:0006357=PMID:8786133, GO:0045944=PMID:20093779, GO:0005634=GO_REF:0000039, GO:0048511=GO_REF:0000037} Q10586 D site-binding protein protein 20111215 {GO:0001889=IEA, GO:0043565=IEA, GO:0001077=IDA, GO:0000977=IDA, GO:0003700=IEA, GO:0006357=TAS, GO:0045944=IDA, GO:0005634=IEA, GO:0048511=IEA} liver development, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, rhythmic process nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II regulatory region sequence-specific DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human DBR1 UniProtKB UniProtKB {GO:0008419=PMID:10982890, GO:0016787=GO_REF:0000002, GO:0000398=GO_REF:0000019, GO:0000375=PMID:10982890, GO:0016788=GO_REF:0000002, GO:0005634=PMID:10982890, GO:0046872=GO_REF:0000037} Q9UK59 Lariat debranching enzyme protein 20061214 {GO:0008419=IMP, GO:0016787=IEA, GO:0000398=IEA, GO:0000375=IMP, GO:0016788=IEA, GO:0005634=IDA, GO:0046872=IEA} RNA splicing, via transesterification reactions, mRNA splicing, via spliceosome nucleus RNA lariat debranching enzyme activity, hydrolase activity, hydrolase activity, acting on ester bonds, metal ion binding Human DBT HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0042645=PMID:18063578, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000052, GO:0048037=GO_REF:0000002, GO:0005759=Reactome:REACT_1813, GO:0015630=GO_REF:0000052, GO:0043754=GO_REF:0000002, GO:0005947=PMID:1429740, GO:0009083=Reactome:REACT_197, GO:0044281=Reactome:REACT_111217, GO:0046949=GO_REF:0000002} Q5VVL7 Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial protein 20100326 {GO:0005739=IDA, GO:0042645=IDA, GO:0034641=TAS, GO:0005737=IDA, GO:0048037=IEA, GO:0005759=TAS, GO:0015630=IDA, GO:0043754=IEA, GO:0005947=TAS, GO:0009083=TAS, GO:0044281=TAS, GO:0046949=IEA} branched-chain amino acid catabolic process, cellular nitrogen compound metabolic process, fatty-acyl-CoA biosynthetic process, small molecule metabolic process cytoplasm, microtubule cytoskeleton, mitochondrial alpha-ketoglutarate dehydrogenase complex, mitochondrial matrix, mitochondrial nucleoid, mitochondrion cofactor binding, dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity Human DCAF10 UniProtKB UniProtKB {GO:0016567=PMID:16949367, GO:0080008=PMID:16949367} Q5QP82 DDB1- and CUL4-associated factor 10 protein 20091211 {GO:0016567=IC, GO:0080008=IDA} protein ubiquitination Cul4-RING ubiquitin ligase complex Human DCAF11 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0016567=PMID:16949367, GO:0080008=PMID:16949367} Q8TEB1 DDB1- and CUL4-associated factor 11 protein 20130415 {GO:0005515=IPI, GO:0016567=IC, GO:0080008=IDA} protein ubiquitination Cul4-RING ubiquitin ligase complex protein binding Human UniProtKB:P12504 DCAF12 UniProtKB UniProtKB {GO:0005737=PMID:18957058, GO:0005813=PMID:18957058, GO:0016567=PMID:16949367, GO:0080008=PMID:16949367} Q5T6F0 DDB1- and CUL4-associated factor 12 protein 20091211 {GO:0005737=IDA, GO:0005813=IDA, GO:0016567=IC, GO:0080008=IDA} protein ubiquitination Cul4-RING ubiquitin ligase complex, centrosome, cytoplasm Human GO:0080008 DCAF12L2 null null {} null null null null {} null null null DCAF13 UniProtKB UniProtKB {GO:0016567=PMID:16949367, GO:0030529=GO_REF:0000037, GO:0006364=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0080008=PMID:16949367} Q9NV06 DDB1- and CUL4-associated factor 13 protein 20091211 {GO:0016567=IC, GO:0030529=IEA, GO:0006364=IEA, GO:0005730=IEA, GO:0080008=IDA} protein ubiquitination, rRNA processing Cul4-RING ubiquitin ligase complex, nucleolus, ribonucleoprotein complex Human DCAF15 UniPathway UniProtKB {GO:0016567=GO_REF:0000041} Q66K64 DDB1- and CUL4-associated factor 15 protein 20130413 {GO:0016567=IEA} protein ubiquitination Human UniPathway:UPA00143 DCAF16 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0016567=PMID:16949367, GO:0080008=PMID:16949367} Q9NXF7 DDB1- and CUL4-associated factor 16 protein 20130415 {GO:0005515=IPI, GO:0016567=IC, GO:0080008=IDA} protein ubiquitination Cul4-RING ubiquitin ligase complex protein binding Human UniProtKB:P04608 DCAF17 UniProtKB UniProtKB {GO:0016567=PMID:16949367, GO:0005730=GO_REF:0000039, GO:0080008=PMID:16949367, GO:0016021=GO_REF:0000037} Q5H9S7 DDB1- and CUL4-associated factor 17 protein 20091211 {GO:0016567=IC, GO:0005730=IEA, GO:0080008=IDA, GO:0016021=IEA} protein ubiquitination Cul4-RING ubiquitin ligase complex, integral to membrane, nucleolus Human DCAF4 UniProtKB UniProtKB {GO:0016567=PMID:16949367, GO:0080008=PMID:16949367} Q8WV16 DDB1- and CUL4-associated factor 4 protein 20091211 {GO:0016567=IC, GO:0080008=IDA} protein ubiquitination Cul4-RING ubiquitin ligase complex Human GO:0080008 DCAF4L1 null null {} null null null null {} null null null DCAF5 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0016567=PMID:16949367, GO:0080008=PMID:16949367} Q96JK2 DDB1- and CUL4-associated factor 5 protein 20091211 {GO:0005739=IEA, GO:0016567=IC, GO:0080008=IDA} protein ubiquitination Cul4-RING ubiquitin ligase complex, mitochondrion Human GO:0080008 DCAF6 MGI UniProtKB {GO:0030374=PMID:15784617, GO:0016567=PMID:16949367, GO:0045944=PMID:15784617, GO:0005634=PMID:15784617, GO:0080008=PMID:16949367} Q58WW2 DDB1- and CUL4-associated factor 6 protein 20100304 {GO:0030374=IDA, GO:0016567=IC, GO:0045944=IGI, GO:0005634=IDA, GO:0080008=IDA} positive regulation of transcription from RNA polymerase II promoter, protein ubiquitination Cul4-RING ubiquitin ligase complex, nucleus ligand-dependent nuclear receptor transcription coactivator activity Human UniProtKB:P10275 DCAF7 HPA UniProtKB {GO:0005515=PMID:21328542, GO:0005737=GO_REF:0000052, GO:0016567=PMID:16949367, GO:0005730=GO_REF:0000052, GO:0007275=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0080008=PMID:16949367} P61962 DDB1- and CUL4-associated factor 7 protein 20101115 {GO:0005515=IPI, GO:0005737=IDA, GO:0016567=IC, GO:0005730=IDA, GO:0007275=IEA, GO:0005634=IDA, GO:0080008=IDA} multicellular organismal development, protein ubiquitination Cul4-RING ubiquitin ligase complex, cytoplasm, nucleolus, nucleus protein binding Human DCAF8 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0016567=PMID:16949367, GO:0080008=PMID:16949367, GO:0005777=GO_REF:0000002} Q5TAQ9 DDB1- and CUL4-associated factor 8 protein 20130415 {GO:0005515=IPI, GO:0016567=IC, GO:0080008=IDA, GO:0005777=IEA} protein ubiquitination Cul4-RING ubiquitin ligase complex, peroxisome protein binding Human UniProtKB:P12520 DCAF8L2 null null {} null null null null {} null null null DCAKD ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0004140=GO_REF:0000002, GO:0015937=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q8WVC6 Dephospho-CoA kinase domain-containing protein protein 20130413 {GO:0005739=IEA, GO:0004140=IEA, GO:0015937=IEA, GO:0005524=IEA} coenzyme A biosynthetic process mitochondrion ATP binding, dephospho-CoA kinase activity Human Ensembl:ENSMUSP00000021313 DCBLD1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000002} Q8N8Z6 Discoidin, CUB and LCCL domain-containing protein 1 protein 20130413 {GO:0016021=IEA, GO:0007155=IEA} cell adhesion integral to membrane Human UniProtKB-KW:KW-0812 DCBLD2 UniProtKB UniProtKB {GO:0030308=PMID:11447234, GO:0009986=PMID:11447234, GO:0005887=PMID:11447234, GO:0042060=PMID:11447234, GO:0007155=GO_REF:0000002, GO:0030522=PMID:11447234} Q96PD2 Discoidin, CUB and LCCL domain-containing protein 2 protein 20031216 {GO:0030308=IDA, GO:0009986=IDA, GO:0005887=IDA, GO:0042060=IDA, GO:0007155=IEA, GO:0030522=NAS} cell adhesion, intracellular receptor signaling pathway, negative regulation of cell growth, wound healing cell surface, integral to plasma membrane Human DCC BHF-UCL UniProtKB {GO:0005515=PMID:20434207, GO:0030424=GO_REF:0000019, GO:0005886=Reactome:REACT_22440, GO:0021965=GO_REF:0000019, GO:0007409=PMID:8861902, GO:0033563=GO_REF:0000019, GO:0048671=PMID:19616629, GO:0042802=GO_REF:0000019, GO:0005829=Reactome:REACT_22440, GO:0005042=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0070374=GO_REF:0000019, GO:2000171=PMID:19616629, GO:0003713=GO_REF:0000019, GO:0032584=GO_REF:0000019, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0006917=PMID:9796814, GO:0001975=GO_REF:0000019, GO:0010976=GO_REF:0000019, GO:0010977=PMID:19616629, GO:0045121=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0001764=GO_REF:0000019, GO:0004888=PMID:8861902} P43146 Netrin receptor DCC protein 20110427 {GO:0005515=IPI, GO:0030424=IEA, GO:0005886=TAS, GO:0021965=IEA, GO:0007409=TAS, GO:0033563=IEA, GO:0048671=TAS, GO:0042802=IEA, GO:0005829=TAS, GO:0005042=IEA, GO:0007411=TAS, GO:0070374=IEA, GO:2000171=TAS, GO:0003713=IEA, GO:0032584=IEA, GO:0006915=TAS, GO:0042981=TAS, GO:0006917=TAS, GO:0001975=IEA, GO:0010976=IEA, GO:0010977=TAS, GO:0045121=IEA, GO:0016021=IEA, GO:0001764=IEA, GO:0004888=TAS} apoptotic process, axon guidance, axonogenesis, dorsal/ventral axon guidance, induction of apoptosis, negative regulation of collateral sprouting, negative regulation of dendrite development, negative regulation of neuron projection development, neuron migration, positive regulation of ERK1 and ERK2 cascade, positive regulation of neuron projection development, regulation of apoptotic process, response to amphetamine, spinal cord ventral commissure morphogenesis axon, cytosol, growth cone membrane, integral to membrane, membrane raft, plasma membrane identical protein binding, netrin receptor activity, protein binding, transcription coactivator activity, transmembrane signaling receptor activity Human DCD UniProtKB UniProtKB {GO:0050832=GO_REF:0000037, GO:0031640=GO_REF:0000037, GO:0006508=GO_REF:0000037, GO:0005576=PMID:9736629, GO:0008233=GO_REF:0000037, GO:0042742=GO_REF:0000037} P81605 Dermcidin protein 20010828 {GO:0050832=IEA, GO:0031640=IEA, GO:0006508=IEA, GO:0005576=IDA, GO:0008233=IEA, GO:0042742=IEA} defense response to bacterium, defense response to fungus, killing of cells of other organism, proteolysis extracellular region peptidase activity Human DCDC2 PINC UniProtKB {GO:0035556=GO_REF:0000002, GO:0048813=GO_REF:0000019, GO:0006968=PMID:10601354, GO:0001764=GO_REF:0000024} Q9UHG0 Doublecortin domain-containing protein 2 protein 20050308 {GO:0035556=IEA, GO:0048813=IEA, GO:0006968=TAS, GO:0001764=ISS} cellular defense response, dendrite morphogenesis, intracellular signal transduction, neuron migration Human DCHS1 UniProtKB UniProtKB {GO:0016339=PMID:9199196, GO:0016020=PMID:9199196, GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000002} Q96JQ0 Protocadherin-16 protein 20021105 {GO:0016339=NAS, GO:0016020=NAS, GO:0005886=IEA, GO:0005509=IEA, GO:0016021=IEA, GO:0007156=IEA} calcium-dependent cell-cell adhesion, homophilic cell adhesion integral to membrane, membrane, plasma membrane calcium ion binding Human DCHS2 UniProtKB UniProtKB {GO:0005886=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000002} Q6V1P9 Protocadherin-23 protein 20130413 {GO:0005886=IEA, GO:0005509=IEA, GO:0016021=IEA, GO:0007156=IEA} homophilic cell adhesion integral to membrane, plasma membrane calcium ion binding Human UniProtKB-KW:KW-0812 DCK GOC UniProtKB {GO:0055086=Reactome:REACT_1698, GO:0005634=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0006220=PMID:12808445, GO:0043097=Reactome:REACT_655, GO:0019206=Reactome:REACT_1547, GO:0005524=GO_REF:0000037, GO:0009165=Reactome:REACT_1547, GO:0042803=PMID:12808445, GO:0005829=Reactome:REACT_1547, GO:0006139=GO_REF:0000002, GO:0006144=Reactome:REACT_522, GO:0008144=PMID:12808445, GO:0043101=Reactome:REACT_1923, GO:0016773=GO_REF:0000002, GO:0004137=PMID:12808445, GO:0006206=Reactome:REACT_957} P27707 Deoxycytidine kinase protein 20130413 {GO:0055086=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0006220=IDA, GO:0043097=TAS, GO:0019206=EXP, GO:0005524=IEA, GO:0009165=EXP, GO:0042803=IPI, GO:0005829=TAS, GO:0006139=IEA, GO:0006144=TAS, GO:0008144=IDA, GO:0043101=TAS, GO:0016773=IEA, GO:0004137=IDA, GO:0006206=TAS} nucleobase-containing compound metabolic process, nucleobase-containing small molecule metabolic process, nucleotide biosynthetic process, purine nucleobase metabolic process, purine-containing compound salvage, pyrimidine nucleobase metabolic process, pyrimidine nucleoside salvage, pyrimidine nucleotide metabolic process, small molecule metabolic process cytosol, nucleus ATP binding, deoxycytidine kinase activity, drug binding, nucleoside kinase activity, phosphotransferase activity, alcohol group as acceptor, protein homodimerization activity Human DCLK1 InterPro UniProtKB {GO:0021952=GO_REF:0000019, GO:0048675=GO_REF:0000019, GO:0007417=PMID:10051403, GO:0009615=PMID:16548883, GO:0005524=GO_REF:0000037, GO:0007399=PMID:10036192, GO:0035556=GO_REF:0000002, GO:0048813=GO_REF:0000019, GO:0004672=PMID:9747029, GO:0004674=GO_REF:0000037, GO:0005887=PMID:10036192, GO:0016197=PMID:14613930, GO:0006468=PMID:9747029, GO:0030900=GO_REF:0000019, GO:0005057=PMID:10036192, GO:0001764=GO_REF:0000019} Q5VZY9 Serine/threonine-protein kinase DCLK1 protein 20130413 {GO:0021952=IEA, GO:0048675=IEA, GO:0007417=TAS, GO:0009615=IEP, GO:0005524=IEA, GO:0007399=TAS, GO:0035556=IEA, GO:0048813=IEA, GO:0004672=TAS, GO:0004674=IEA, GO:0005887=TAS, GO:0016197=NAS, GO:0006468=TAS, GO:0030900=IEA, GO:0005057=TAS, GO:0001764=IEA} axon extension, central nervous system development, central nervous system projection neuron axonogenesis, dendrite morphogenesis, endosomal transport, forebrain development, intracellular signal transduction, nervous system development, neuron migration, protein phosphorylation, response to virus integral to plasma membrane ATP binding, protein kinase activity, protein serine/threonine kinase activity, receptor signaling protein activity Human InterPro:IPR003533 DCLK2 UniProtKB UniProtKB {GO:0035556=GO_REF:0000002, GO:0005737=GO_REF:0000037, GO:0004674=GO_REF:0000037, GO:0005856=GO_REF:0000039, GO:0005524=GO_REF:0000037} Q8N568 Serine/threonine-protein kinase DCLK2 protein 20130413 {GO:0035556=IEA, GO:0005737=IEA, GO:0004674=IEA, GO:0005856=IEA, GO:0005524=IEA} intracellular signal transduction cytoplasm, cytoskeleton ATP binding, protein serine/threonine kinase activity Human UniProtKB-SubCell:SL-0090 DCLK3 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0004674=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0005524=GO_REF:0000037} Q9C098 Serine/threonine-protein kinase DCLK3 protein 20130413 {GO:0005737=IEA, GO:0004674=IEA, GO:0005634=IEA, GO:0005524=IEA} cytoplasm, nucleus ATP binding, protein serine/threonine kinase activity Human UniProtKB-SubCell:SL-0086 DCLRE1A HPA UniProtKB {GO:0007067=GO_REF:0000037, GO:0016787=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006289=GO_REF:0000019, GO:0051301=GO_REF:0000037} Q6PJP8 DNA cross-link repair 1A protein protein 20110516 {GO:0007067=IEA, GO:0016787=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006289=IEA, GO:0051301=IEA} cell division, mitosis, nucleotide-excision repair nucleolus, nucleus hydrolase activity Human DCLRE1B IntAct UniProtKB {GO:0005515=PMID:16730175, GO:0000781=PMID:16730175, GO:0005813=PMID:19197158, GO:0005737=GO_REF:0000037, GO:0008409=PMID:16730175, GO:0006281=GO_REF:0000037, GO:0031860=GO_REF:0000024, GO:0000723=PMID:20655466, GO:0000075=PMID:19197158, GO:0005634=GO_REF:0000039, GO:0031627=GO_REF:0000024, GO:0031848=PMID:16730175} Q9H816 5' exonuclease Apollo protein 20130415 {GO:0005515=IPI, GO:0000781=IDA, GO:0005813=IDA, GO:0005737=IEA, GO:0008409=IDA, GO:0006281=IEA, GO:0031860=ISS, GO:0000723=IMP, GO:0000075=IMP, GO:0005634=IEA, GO:0031627=ISS, GO:0031848=IMP} DNA repair, cell cycle checkpoint, protection from non-homologous end joining at telomere, telomere maintenance, telomeric 3' overhang formation, telomeric loop formation centrosome, chromosome, telomeric region, cytoplasm, nucleus 5'-3' exonuclease activity, protein binding Human UniProtKB:Q15554 DCLRE1C MGI UniProtKB {GO:0008409=PMID:11955432, GO:0000723=GO_REF:0000019, GO:0010212=GO_REF:0000019, GO:0030183=GO_REF:0000019, GO:0000014=PMID:11955432, GO:0005634=GO_REF:0000039, GO:0006310=GO_REF:0000019, GO:0006302=GO_REF:0000019} Q96SD1 Protein artemis protein 20091019 {GO:0008409=IDA, GO:0000723=IEA, GO:0010212=IEA, GO:0030183=IEA, GO:0000014=IDA, GO:0005634=IEA, GO:0006310=IEA, GO:0006302=IEA} B cell differentiation, DNA recombination, double-strand break repair, response to ionizing radiation, telomere maintenance nucleus 5'-3' exonuclease activity, single-stranded DNA specific endodeoxyribonuclease activity Human DCN BHF-UCL UniProtKB {GO:0019800=GO_REF:0000019, GO:0005518=GO_REF:0000019, GO:0005589=GO_REF:0000019, GO:0005539=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0030208=Reactome:REACT_120800, GO:0030207=Reactome:REACT_120888, GO:0030206=Reactome:REACT_120989, GO:0032496=GO_REF:0000019, GO:0009887=PMID:7961765, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408, GO:0043202=Reactome:REACT_121272, GO:0001822=GO_REF:0000019, GO:0005796=Reactome:REACT_121341, GO:0005975=Reactome:REACT_474, GO:0007568=GO_REF:0000019, GO:0050840=GO_REF:0000019, GO:0005576=Reactome:REACT_121341, GO:0001890=GO_REF:0000019, GO:0009612=GO_REF:0000019, GO:0031012=PMID:22261194, GO:0047485=GO_REF:0000019, GO:0007519=GO_REF:0000019, GO:0042060=GO_REF:0000019} P07585 Decorin protein 20120228 {GO:0019800=IEA, GO:0005518=IEA, GO:0005589=IEA, GO:0005539=IEA, GO:0044281=TAS, GO:0030208=TAS, GO:0030207=TAS, GO:0030206=TAS, GO:0032496=IEA, GO:0009887=TAS, GO:0030204=TAS, GO:0030203=TAS, GO:0043202=TAS, GO:0001822=IEA, GO:0005796=TAS, GO:0005975=TAS, GO:0007568=IEA, GO:0050840=IEA, GO:0005576=TAS, GO:0001890=IEA, GO:0009612=IEA, GO:0031012=ISS, GO:0047485=IEA, GO:0007519=IEA, GO:0042060=IEA} aging, carbohydrate metabolic process, chondroitin sulfate biosynthetic process, chondroitin sulfate catabolic process, chondroitin sulfate metabolic process, dermatan sulfate biosynthetic process, glycosaminoglycan metabolic process, kidney development, organ morphogenesis, peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan, placenta development, response to lipopolysaccharide, response to mechanical stimulus, skeletal muscle tissue development, small molecule metabolic process, wound healing Golgi lumen, collagen type VI, extracellular matrix, extracellular region, lysosomal lumen collagen binding, extracellular matrix binding, glycosaminoglycan binding, protein N-terminus binding colocalizes_with Human UniProtKB:Q9XSD9 DCP1A IntAct UniProtKB {GO:0005515=PMID:16364915, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016787=GO_REF:0000037, GO:0000184=GO_REF:0000037, GO:0016071=Reactome:REACT_20605, GO:0000932=GO_REF:0000024, GO:0043928=Reactome:REACT_20518, GO:0005634=GO_REF:0000039, GO:0042802=PMID:16364915, GO:0005829=Reactome:REACT_25297, GO:0000288=Reactome:REACT_20639} Q9NPI6 mRNA-decapping enzyme 1A protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0016787=IEA, GO:0000184=IEA, GO:0016071=TAS, GO:0000932=ISS, GO:0043928=TAS, GO:0005634=IEA, GO:0042802=IPI, GO:0005829=TAS, GO:0000288=TAS} RNA metabolic process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay cytoplasmic mRNA processing body, cytosol, nucleus hydrolase activity, identical protein binding, protein binding Human UniProtKB:Q9NPI6 DCP1B HPA UniProtKB {GO:0005515=PMID:16364915, GO:0010467=Reactome:REACT_71, GO:0005737=GO_REF:0000052, GO:0016070=Reactome:REACT_21257, GO:0016787=GO_REF:0000037, GO:0000184=GO_REF:0000037, GO:0016071=Reactome:REACT_20605, GO:0043928=Reactome:REACT_20518, GO:0005634=GO_REF:0000039, GO:0005829=Reactome:REACT_20560, GO:0000288=Reactome:REACT_20639, GO:0043231=GO_REF:0000052} Q8IZD4 mRNA-decapping enzyme 1B protein 20110516 {GO:0005515=IPI, GO:0010467=TAS, GO:0005737=IDA, GO:0016070=TAS, GO:0016787=IEA, GO:0000184=IEA, GO:0016071=TAS, GO:0043928=TAS, GO:0005634=IEA, GO:0005829=TAS, GO:0000288=TAS, GO:0043231=IDA} RNA metabolic process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay cytoplasm, cytosol, intracellular membrane-bounded organelle, nucleus hydrolase activity, protein binding Human DCP2 IntAct UniProtKB {GO:0005515=PMID:16364915, GO:0010467=Reactome:REACT_71, GO:0016896=Reactome:REACT_20560, GO:0030145=GO_REF:0000002, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=GO_REF:0000037, GO:0043928=Reactome:REACT_20518, GO:0005634=GO_REF:0000039, GO:0006402=PMID:21070968, GO:0050072=PMID:21070968, GO:0016442=PMID:20616046, GO:0005829=Reactome:REACT_25297, GO:0016787=GO_REF:0000038, GO:0000184=PMID:22890540, GO:0000932=PMID:20616046, GO:0071044=PMID:18172165, GO:0000288=Reactome:REACT_20639} Q8IU60 m7GpppN-mRNA hydrolase protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0016896=TAS, GO:0030145=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=IEA, GO:0043928=TAS, GO:0005634=IEA, GO:0006402=IDA, GO:0050072=IDA, GO:0016442=IDA, GO:0005829=TAS, GO:0016787=IEA, GO:0000184=IMP, GO:0000932=IDA, GO:0071044=IMP, GO:0000288=TAS} RNA metabolic process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, histone mRNA catabolic process, mRNA catabolic process, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay RNA-induced silencing complex, cytoplasmic mRNA processing body, cytosol, nucleus RNA binding, exoribonuclease activity, producing 5'-phosphomonoesters, hydrolase activity, m7G(5')pppN diphosphatase activity, manganese ion binding, protein binding Human UniProtKB:Q9NPI6 DCPS HPA UniProtKB {GO:0005515=PMID:16140270, GO:0036245=PMID:16140270, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0045292=PMID:18426921, GO:0005730=GO_REF:0000052, GO:0043928=Reactome:REACT_20619, GO:0000290=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0050072=PMID:18426921, GO:0005829=Reactome:REACT_20556, GO:0005739=GO_REF:0000052, GO:0043069=PMID:16140270, GO:0005737=PMID:18441014, GO:0000340=PMID:18426921, GO:0000288=Reactome:REACT_20639} Q96C86 m7GpppX diphosphatase protein 20110516 {GO:0005515=IPI, GO:0036245=IDA, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0045292=IDA, GO:0005730=IDA, GO:0043928=TAS, GO:0000290=IEA, GO:0005634=IDA, GO:0050072=IDA, GO:0005829=TAS, GO:0005739=IDA, GO:0043069=IDA, GO:0005737=IDA, GO:0000340=IDA, GO:0000288=TAS} RNA metabolic process, cellular response to menadione, deadenylation-dependent decapping of nuclear-transcribed mRNA, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, mRNA cis splicing, via spliceosome, mRNA metabolic process, negative regulation of programmed cell death, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay cytoplasm, cytosol, mitochondrion, nucleolus, nucleus RNA 7-methylguanosine cap binding, m7G(5')pppN diphosphatase activity, protein binding Human DCST1 UniProtKB UniProtKB {GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q5T197 DC-STAMP domain-containing protein 1 protein 20130413 {GO:0008270=IEA, GO:0016021=IEA} integral to membrane zinc ion binding Human UniProtKB-KW:KW-0812 DCST2 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q5T1A1 DC-STAMP domain-containing protein 2 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 DCT PINC UniProtKB {GO:0033162=GO_REF:0000039, GO:0042470=GO_REF:0000024, GO:0021847=GO_REF:0000019, GO:0005507=PMID:8206391, GO:0002052=GO_REF:0000019, GO:0046872=GO_REF:0000038, GO:0005829=GO_REF:0000024, GO:0004167=GO_REF:0000024, GO:0008544=PMID:8206391, GO:0006583=GO_REF:0000024, GO:0016491=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0048468=GO_REF:0000019, GO:0048066=GO_REF:0000019} P40126 L-dopachrome tautomerase protein 20030904 {GO:0033162=IEA, GO:0042470=ISS, GO:0021847=IEA, GO:0005507=TAS, GO:0002052=IEA, GO:0046872=IEA, GO:0005829=ISS, GO:0004167=ISS, GO:0008544=TAS, GO:0006583=ISS, GO:0016491=IEA, GO:0016021=IEA, GO:0048468=IEA, GO:0048066=IEA} cell development, developmental pigmentation, epidermis development, melanin biosynthetic process from tyrosine, positive regulation of neuroblast proliferation, ventricular zone neuroblast division cytosol, integral to membrane, melanosome, melanosome membrane copper ion binding, dopachrome isomerase activity, metal ion binding, oxidoreductase activity Human DCTD Reactome UniProtKB {GO:0046134=Reactome:REACT_21376, GO:0016787=GO_REF:0000002, GO:0016810=GO_REF:0000002, GO:0055086=Reactome:REACT_1698, GO:0008270=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0006220=PMID:7685356, GO:0006206=Reactome:REACT_957, GO:0004132=Reactome:REACT_879, GO:0009165=GO_REF:0000037, GO:0005829=Reactome:REACT_879} P32321 Deoxycytidylate deaminase protein 20130213 {GO:0046134=TAS, GO:0016787=IEA, GO:0016810=IEA, GO:0055086=TAS, GO:0008270=IEA, GO:0044281=TAS, GO:0006220=TAS, GO:0006206=TAS, GO:0004132=EXP, GO:0009165=IEA, GO:0005829=TAS} nucleobase-containing small molecule metabolic process, nucleotide biosynthetic process, pyrimidine nucleobase metabolic process, pyrimidine nucleoside biosynthetic process, pyrimidine nucleotide metabolic process, small molecule metabolic process cytosol dCMP deaminase activity, hydrolase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, zinc ion binding Human DCTN1 IntAct UniProtKB {GO:0005515=PMID:18000879, GO:0008219=GO_REF:0000037, GO:0005813=PMID:21399614, GO:0005874=PMID:21525035, GO:0030968=Reactome:REACT_18356, GO:0005829=Reactome:REACT_120995, GO:0007399=PMID:17360970, GO:0019886=Reactome:REACT_121399, GO:0003774=GO_REF:0000037, GO:0000922=PMID:14718566, GO:0005737=PMID:1828535, GO:0007067=PMID:1828535, GO:0030286=GO_REF:0000037, GO:0000086=Reactome:REACT_2203, GO:0006810=GO_REF:0000037, GO:0000776=PMID:19468067, GO:0006987=Reactome:REACT_18368, GO:0000278=Reactome:REACT_152, GO:0044267=Reactome:REACT_17015, GO:0031252=GO_REF:0000019} Q14203 Dynactin subunit 1 protein 20130415 {GO:0005515=IPI, GO:0008219=IEA, GO:0005813=IDA, GO:0005874=IDA, GO:0030968=TAS, GO:0005829=TAS, GO:0007399=NAS, GO:0019886=TAS, GO:0003774=IEA, GO:0000922=IDA, GO:0005737=TAS, GO:0007067=NAS, GO:0030286=IEA, GO:0000086=TAS, GO:0006810=IEA, GO:0000776=IDA, GO:0006987=TAS, GO:0000278=TAS, GO:0044267=TAS, GO:0031252=IEA} G2/M transition of mitotic cell cycle, activation of signaling protein activity involved in unfolded protein response, antigen processing and presentation of exogenous peptide antigen via MHC class II, cell death, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, mitosis, mitotic cell cycle, nervous system development, transport cell leading edge, centrosome, cytoplasm, cytosol, dynein complex, kinetochore, microtubule, spindle pole motor activity, protein binding Human UniProtKB:Q96RK4 DCTN2 HPA UniProtKB {GO:0005515=PMID:17043677, GO:0005813=GO_REF:0000052, GO:0008283=PMID:8647893, GO:0005874=GO_REF:0000037, GO:0031982=PMID:20682791, GO:0005829=Reactome:REACT_120995, GO:0030426=GO_REF:0000019, GO:0019886=Reactome:REACT_121399, GO:0005737=GO_REF:0000052, GO:0003774=GO_REF:0000037, GO:0007067=PMID:8647893, GO:0030286=GO_REF:0000037, GO:0016020=GO_REF:0000039, GO:0000086=Reactome:REACT_2203, GO:0000776=PMID:8647893, GO:0000278=Reactome:REACT_152, GO:0007017=GO_REF:0000002, GO:0007052=GO_REF:0000019, GO:0005869=PMID:8647893} Q13561 Dynactin subunit 2 protein 20120912 {GO:0005515=IPI, GO:0005813=IDA, GO:0008283=IMP, GO:0005874=IEA, GO:0031982=IDA, GO:0005829=TAS, GO:0030426=IEA, GO:0019886=TAS, GO:0005737=IDA, GO:0003774=IEA, GO:0007067=IMP, GO:0030286=IEA, GO:0016020=IEA, GO:0000086=TAS, GO:0000776=IDA, GO:0000278=TAS, GO:0007017=IEA, GO:0007052=IEA, GO:0005869=IDA} G2/M transition of mitotic cell cycle, antigen processing and presentation of exogenous peptide antigen via MHC class II, cell proliferation, microtubule-based process, mitosis, mitotic cell cycle, mitotic spindle organization centrosome, cytoplasm, cytosol, dynactin complex, dynein complex, growth cone, kinetochore, membrane, microtubule, vesicle motor activity, protein binding Human DCTN3 Reactome UniProtKB {GO:0005515=PMID:9722614, GO:0048471=PMID:9722614, GO:0005813=PMID:21399614, GO:0005819=GO_REF:0000039, GO:0030496=GO_REF:0000039, GO:0032154=GO_REF:0000039, GO:0005829=Reactome:REACT_120995, GO:0019886=Reactome:REACT_121399, GO:0000910=PMID:9722614, GO:0007067=GO_REF:0000037, GO:0005198=PMID:9722614, GO:0000086=Reactome:REACT_2203, GO:0000777=GO_REF:0000039, GO:0007017=GO_REF:0000019, GO:0005869=PMID:9722614, GO:0000278=Reactome:REACT_152} O75935 Dynactin subunit 3 protein 20130301 {GO:0005515=IPI, GO:0048471=IDA, GO:0005813=IDA, GO:0005819=IEA, GO:0030496=IEA, GO:0032154=IEA, GO:0005829=TAS, GO:0019886=TAS, GO:0000910=IDA, GO:0007067=IEA, GO:0005198=TAS, GO:0000086=TAS, GO:0000777=IEA, GO:0007017=IEA, GO:0005869=IPI, GO:0000278=TAS} G2/M transition of mitotic cell cycle, antigen processing and presentation of exogenous peptide antigen via MHC class II, cytokinesis, microtubule-based process, mitosis, mitotic cell cycle centrosome, cleavage furrow, condensed chromosome kinetochore, cytosol, dynactin complex, midbody, perinuclear region of cytoplasm, spindle protein binding, structural molecule activity Human DCTN4 Reactome UniProtKB {GO:0019886=Reactome:REACT_121399, GO:0005737=PMID:10671518, GO:0005813=PMID:21399614, GO:0047485=PMID:16554302, GO:0005634=PMID:10671518, GO:0005829=Reactome:REACT_120995} Q9UJW0 Dynactin subunit 4 protein 20130301 {GO:0019886=TAS, GO:0005737=TAS, GO:0005813=IDA, GO:0047485=IPI, GO:0005634=TAS, GO:0005829=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II centrosome, cytoplasm, cytosol, nucleus protein N-terminus binding Human DCTN5 Reactome UniProtKB {GO:0019886=Reactome:REACT_121399, GO:0005813=PMID:21399614, GO:0016740=GO_REF:0000002, GO:0005829=Reactome:REACT_120995} Q9BTE1 Dynactin subunit 5 protein 20130301 {GO:0019886=TAS, GO:0005813=IDA, GO:0016740=IEA, GO:0005829=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II centrosome, cytosol transferase activity Human DCTN6 Reactome UniProtKB {GO:0019886=Reactome:REACT_121399, GO:0005813=PMID:21399614, GO:0045502=GO_REF:0000019, GO:0005869=GO_REF:0000019, GO:0016740=GO_REF:0000002, GO:0005829=Reactome:REACT_120995} O00399 Dynactin subunit 6 protein 20130301 {GO:0019886=TAS, GO:0005813=IDA, GO:0045502=IEA, GO:0005869=IEA, GO:0016740=IEA, GO:0005829=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II centrosome, cytosol, dynactin complex dynein binding, transferase activity Human DCTPP1 UniProtKB UniProtKB {GO:0032556=GO_REF:0000019, GO:0000287=GO_REF:0000024, GO:0051289=GO_REF:0000019, GO:0047429=GO_REF:0000024, GO:0009143=GO_REF:0000024, GO:0047840=GO_REF:0000003, GO:0005829=GO_REF:0000024} Q9H773 dCTP pyrophosphatase 1 protein 20100521 {GO:0032556=IEA, GO:0000287=ISS, GO:0051289=IEA, GO:0047429=ISS, GO:0009143=ISS, GO:0047840=IEA, GO:0005829=ISS} nucleoside triphosphate catabolic process, protein homotetramerization cytosol dCTP diphosphatase activity, magnesium ion binding, nucleoside-triphosphate diphosphatase activity, pyrimidine deoxyribonucleotide binding Human UniProtKB:Q9QY93 DCUN1D1 UniProtKB UniProtKB {GO:0005515=PMID:18826954, GO:0008150=GO_REF:0000015, GO:0000151=PMID:18826954} Q96GG9 DCN1-like protein 1 protein 20100628 {GO:0005515=IPI, GO:0008150=ND, GO:0000151=IDA} biological_process ubiquitin ligase complex protein binding Human UniProtKB:Q86VP6 DCUN1D2 null null {} null null null null {} null null null DCUN1D3 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0030308=PMID:18823379, GO:0010225=PMID:18823379, GO:0048471=PMID:18823379, GO:0043065=PMID:18823379, GO:0010332=PMID:18823379, GO:0045749=PMID:18823379} Q8IWE4 DCN1-like protein 3 protein 20090731 {GO:0003674=ND, GO:0030308=IMP, GO:0010225=IDA, GO:0048471=IDA, GO:0043065=IMP, GO:0010332=IDA, GO:0045749=IMP} negative regulation of S phase of mitotic cell cycle, negative regulation of cell growth, positive regulation of apoptotic process, response to UV-C, response to gamma radiation perinuclear region of cytoplasm molecular_function Human DCUN1D4 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005634=GO_REF:0000054, GO:0005575=GO_REF:0000015} Q92564 DCN1-like protein 4 protein 20100930 {GO:0003674=ND, GO:0008150=ND, GO:0005634=IDA, GO:0005575=ND} biological_process cellular_component, nucleus molecular_function Human DCUN1D5 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q9BTE7 DCN1-like protein 5 protein 20101020 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human DCX Reactome UniProtKB {GO:0008017=PMID:14741102, GO:0043005=PMID:14741102, GO:0019901=PMID:14741102, GO:0005875=PMID:11001923, GO:0005874=GO_REF:0000037, GO:0021952=GO_REF:0000019, GO:0048675=GO_REF:0000019, GO:0007417=PMID:9489699, GO:0005829=Reactome:REACT_22218, GO:0007399=PMID:9489699, GO:0035556=GO_REF:0000002, GO:0005622=GO_REF:0000019, GO:0048813=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0007420=GO_REF:0000019, GO:0001764=PMID:14741102, GO:0005856=PMID:11001923} O43602 Neuronal migration protein doublecortin protein 20090729 {GO:0008017=IDA, GO:0043005=IDA, GO:0019901=IPI, GO:0005875=TAS, GO:0005874=IEA, GO:0021952=IEA, GO:0048675=IEA, GO:0007417=TAS, GO:0005829=TAS, GO:0007399=TAS, GO:0035556=IEA, GO:0005622=IEA, GO:0048813=IEA, GO:0007411=TAS, GO:0007420=IEA, GO:0001764=IDA, GO:0005856=TAS} axon extension, axon guidance, brain development, central nervous system development, central nervous system projection neuron axonogenesis, dendrite morphogenesis, intracellular signal transduction, nervous system development, neuron migration cytoskeleton, cytosol, intracellular, microtubule, microtubule associated complex, neuron projection microtubule binding, protein kinase binding Human DCXR UniProtKB UniProtKB {GO:0005903=GO_REF:0000019, GO:0005881=PMID:23264731, GO:0005997=PMID:11882650, GO:0005902=GO_REF:0000019, GO:0016020=GO_REF:0000039, GO:0051289=PMID:11882650, GO:0016491=GO_REF:0000002, GO:0006006=PMID:11882650, GO:0006739=GO_REF:0000019, GO:0050038=PMID:11882650, GO:0055114=PMID:19442656, GO:0042732=GO_REF:0000037} Q7Z4W1 L-xylulose reductase protein 20130311 {GO:0005903=IEA, GO:0005881=IDA, GO:0005997=IDA, GO:0005902=IEA, GO:0016020=IEA, GO:0051289=IDA, GO:0016491=IEA, GO:0006006=IDA, GO:0006739=IEA, GO:0050038=IDA, GO:0055114=IDA, GO:0042732=IEA} D-xylose metabolic process, NADP metabolic process, glucose metabolic process, oxidation-reduction process, protein homotetramerization, xylulose metabolic process brush border, cytoplasmic microtubule, membrane, microvillus L-xylulose reductase (NADP+) activity, oxidoreductase activity Human DDA1 null null {} null null null null {} null null null DDAH1 BHF-UCL UniProtKB {GO:0007263=PMID:9874257, GO:0016813=GO_REF:0000002, GO:0003824=PMID:9874257, GO:0046872=GO_REF:0000037, GO:0045766=GO_REF:0000019, GO:0045429=GO_REF:0000024, GO:0005739=GO_REF:0000019, GO:0003073=GO_REF:0000024, GO:0005737=GO_REF:0000002, GO:0000052=PMID:19663506, GO:0006527=PMID:9874257, GO:0016597=GO_REF:0000019, GO:0016403=PMID:19663506} O94760 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 protein 20120111 {GO:0007263=TAS, GO:0016813=IEA, GO:0003824=TAS, GO:0046872=IEA, GO:0045766=IEA, GO:0045429=ISS, GO:0005739=IEA, GO:0003073=ISS, GO:0005737=IEA, GO:0000052=IDA, GO:0006527=TAS, GO:0016597=IEA, GO:0016403=IDA} arginine catabolic process, citrulline metabolic process, nitric oxide mediated signal transduction, positive regulation of angiogenesis, positive regulation of nitric oxide biosynthetic process, regulation of systemic arterial blood pressure cytoplasm, mitochondrion amino acid binding, catalytic activity, dimethylargininase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines, metal ion binding Human UniProtKB:Q9CWS0 DDAH2 ENSEMBL UniProtKB {GO:0005515=PMID:19060904, GO:0043066=PMID:16130169, GO:0007263=PMID:10493931, GO:0016813=GO_REF:0000002, GO:0003824=PMID:10493931, GO:0045429=GO_REF:0000024, GO:0006809=PMID:10493931, GO:0005739=GO_REF:0000039, GO:0005737=GO_REF:0000002, GO:0006525=GO_REF:0000019, GO:0000052=PMID:10493931, GO:0006527=PMID:10493931, GO:0016597=GO_REF:0000019, GO:0016403=PMID:10493931} Q5SSV3 N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 protein 20130413 {GO:0005515=IPI, GO:0043066=TAS, GO:0007263=TAS, GO:0016813=IEA, GO:0003824=TAS, GO:0045429=ISS, GO:0006809=TAS, GO:0005739=IEA, GO:0005737=IEA, GO:0006525=IEA, GO:0000052=IDA, GO:0006527=TAS, GO:0016597=IEA, GO:0016403=IDA} arginine catabolic process, arginine metabolic process, citrulline metabolic process, negative regulation of apoptotic process, nitric oxide biosynthetic process, nitric oxide mediated signal transduction, positive regulation of nitric oxide biosynthetic process cytoplasm, mitochondrion amino acid binding, catalytic activity, dimethylargininase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines, protein binding Human Ensembl:ENSRNOP00000001118 DDB1 IntAct UniProtKB {GO:0005515=PMID:23238014, GO:0005634=PMID:20223979, GO:0080008=PMID:18381890, GO:0003676=GO_REF:0000002, GO:0003677=PMID:8798680, GO:0003684=PMID:8407967, GO:0005737=PMID:20223979, GO:0006281=Reactome:REACT_216, GO:0042787=PMID:11673459, GO:0019048=GO_REF:0000037, GO:0000075=PMID:17088560, GO:0031465=PMID:18794347, GO:0043161=PMID:20223979, GO:0005654=Reactome:REACT_2163, GO:0006289=Reactome:REACT_1826, GO:0031464=PMID:20223979, GO:0000718=Reactome:REACT_311, GO:0016055=GO_REF:0000019} Q16531 DNA damage-binding protein 1 protein 20130415 {GO:0005515=IPI, GO:0005634=IDA, GO:0080008=IDA, GO:0003676=IEA, GO:0003677=TAS, GO:0003684=TAS, GO:0005737=IDA, GO:0006281=TAS, GO:0042787=IDA, GO:0019048=IEA, GO:0000075=IMP, GO:0031465=IDA, GO:0043161=IMP, GO:0005654=TAS, GO:0006289=TAS, GO:0031464=IDA, GO:0000718=TAS, GO:0016055=IEA} DNA repair, Wnt receptor signaling pathway, cell cycle checkpoint, nucleotide-excision repair, nucleotide-excision repair, DNA damage removal, proteasomal ubiquitin-dependent protein catabolic process, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, virus-host interaction Cul4-RING ubiquitin ligase complex, Cul4A-RING ubiquitin ligase complex, Cul4B-RING ubiquitin ligase complex, cytoplasm, nucleoplasm, nucleus DNA binding, damaged DNA binding, nucleic acid binding, protein binding Human UniProtKB:O75530 DDB2 IntAct UniProtKB {GO:0005515=PMID:19109893, GO:0000209=PMID:12732143, GO:0004842=PMID:12732143, GO:0003677=PMID:8798680, GO:0051865=PMID:12732143, GO:0003684=PMID:8407967, GO:0043234=PMID:12732143, GO:0006290=GO_REF:0000019, GO:0006281=Reactome:REACT_216, GO:0005654=Reactome:REACT_2163, GO:0006289=Reactome:REACT_1826, GO:0000718=Reactome:REACT_311, GO:0009411=PMID:12732143} Q92466 DNA damage-binding protein 2 protein 20130415 {GO:0005515=IPI, GO:0000209=IDA, GO:0004842=IDA, GO:0003677=TAS, GO:0051865=IDA, GO:0003684=TAS, GO:0043234=IDA, GO:0006290=IEA, GO:0006281=TAS, GO:0005654=TAS, GO:0006289=TAS, GO:0000718=TAS, GO:0009411=IDA} DNA repair, nucleotide-excision repair, nucleotide-excision repair, DNA damage removal, protein autoubiquitination, protein polyubiquitination, pyrimidine dimer repair, response to UV nucleoplasm, protein complex DNA binding, damaged DNA binding, protein binding, ubiquitin-protein ligase activity Human UniProtKB:Q16531 DDC IntAct UniProtKB {GO:0005515=PMID:12864730, GO:0030424=GO_REF:0000019, GO:0046684=GO_REF:0000019, GO:0010259=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_15546, GO:0042416=GO_REF:0000041, GO:0034641=Reactome:REACT_13, GO:0043025=GO_REF:0000019, GO:0033076=GO_REF:0000019, GO:0006520=GO_REF:0000002, GO:0019904=GO_REF:0000019, GO:0071312=GO_REF:0000019, GO:0035690=GO_REF:0000019, GO:0008021=GO_REF:0000019, GO:0042427=GO_REF:0000019, GO:0071363=GO_REF:0000019, GO:0046219=Reactome:REACT_15439, GO:0052314=GO_REF:0000019, GO:0030170=GO_REF:0000002, GO:0004058=Reactome:REACT_15546, GO:0016831=GO_REF:0000002, GO:0007623=GO_REF:0000019, GO:0016597=GO_REF:0000019, GO:0015842=GO_REF:0000019, GO:0042423=Reactome:REACT_15551} P20711 Aromatic-L-amino-acid decarboxylase protein 20130415 {GO:0005515=IPI, GO:0030424=IEA, GO:0046684=IEA, GO:0010259=IEA, GO:0044281=TAS, GO:0005829=TAS, GO:0042416=IEA, GO:0034641=TAS, GO:0043025=IEA, GO:0033076=IEA, GO:0006520=IEA, GO:0019904=IEA, GO:0071312=IEA, GO:0035690=IEA, GO:0008021=IEA, GO:0042427=IEA, GO:0071363=IEA, GO:0046219=TAS, GO:0052314=IEA, GO:0030170=IEA, GO:0004058=TAS, GO:0016831=IEA, GO:0007623=IEA, GO:0016597=IEA, GO:0015842=IEA, GO:0042423=TAS} catecholamine biosynthetic process, cellular amino acid metabolic process, cellular nitrogen compound metabolic process, cellular response to alkaloid, cellular response to drug, cellular response to growth factor stimulus, circadian rhythm, dopamine biosynthetic process, indolalkylamine biosynthetic process, isoquinoline alkaloid metabolic process, multicellular organismal aging, phytoalexin metabolic process, response to pyrethroid, serotonin biosynthetic process, small molecule metabolic process, synaptic vesicle amine transport axon, cytosol, neuronal cell body, synaptic vesicle amino acid binding, aromatic-L-amino-acid decarboxylase activity, carboxy-lyase activity, protein binding, protein domain specific binding, pyridoxal phosphate binding Human UniProtKB:P10275 DDHD1 UniProtKB UniProtKB {GO:0016042=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0016787=GO_REF:0000037, GO:0046872=GO_REF:0000002} Q8NEL9 Phospholipase DDHD1 protein 20130413 {GO:0016042=IEA, GO:0005737=IEA, GO:0016787=IEA, GO:0046872=IEA} lipid catabolic process cytoplasm hydrolase activity, metal ion binding Human UniProtKB-SubCell:SL-0086 DDHD2 HPA UniProtKB {GO:0016042=GO_REF:0000037, GO:0005793=GO_REF:0000039, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000039, GO:0016787=GO_REF:0000037, GO:0046872=GO_REF:0000002, GO:0005829=GO_REF:0000039} O94830 Phospholipase DDHD2 protein 20100326 {GO:0016042=IEA, GO:0005793=IEA, GO:0005813=IDA, GO:0005737=IDA, GO:0005794=IEA, GO:0016787=IEA, GO:0046872=IEA, GO:0005829=IEA} lipid catabolic process Golgi apparatus, centrosome, cytoplasm, cytosol, endoplasmic reticulum-Golgi intermediate compartment hydrolase activity, metal ion binding Human DDI1 InterPro UniProtKB {GO:0006508=GO_REF:0000002, GO:0004190=GO_REF:0000002} Q8WTU0 Protein DDI1 homolog 1 protein 20130413 {GO:0006508=IEA, GO:0004190=IEA} proteolysis aspartic-type endopeptidase activity Human InterPro:IPR019103 DDI2 InterPro UniProtKB {GO:0006508=GO_REF:0000002, GO:0004190=GO_REF:0000002} Q5TDH0 Protein DDI1 homolog 2 protein 20130413 {GO:0006508=IEA, GO:0004190=IEA} proteolysis aspartic-type endopeptidase activity Human InterPro:IPR019103 DDIT3 BHF-UCL UniProtKB {GO:0005515=PMID:15775988, GO:0006986=PMID:18940792, GO:0034976=PMID:19061639, GO:0006983=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0005634=PMID:22761832, GO:0043620=PMID:19816510, GO:0043433=PMID:16434966, GO:0045662=GO_REF:0000019, GO:0032757=PMID:20829347, GO:0030968=Reactome:REACT_18356, GO:0005737=GO_REF:0000039, GO:0043525=GO_REF:0000019, GO:0045944=PMID:22065586, GO:0042789=PMID:14667815, GO:0007050=GO_REF:0000037, GO:0016055=GO_REF:0000037, GO:0090090=PMID:16434966, GO:0006355=PMID:22761832, GO:0051209=GO_REF:0000019, GO:2000016=PMID:16434966, GO:0003714=PMID:7503811, GO:0044324=PMID:16434966, GO:0003677=PMID:14667815, GO:0006974=PMID:1339368, GO:0043565=GO_REF:0000002, GO:0070059=PMID:15322075, GO:0005654=Reactome:REACT_115551, GO:0045454=PMID:14667815, GO:0043161=PMID:17872950, GO:0006987=Reactome:REACT_18348, GO:0045893=PMID:15775988, GO:0044267=Reactome:REACT_17015, GO:0001955=GO_REF:0000019, GO:0045892=PMID:18940792, GO:0008134=PMID:16434966} P35638 DNA damage-inducible transcript 3 protein protein 20100715 {GO:0005515=IPI, GO:0006986=IDA, GO:0034976=IDA, GO:0006983=IEA, GO:0003700=IEA, GO:0005634=IDA, GO:0043620=TAS, GO:0043433=IDA, GO:0045662=IEA, GO:0032757=IMP, GO:0030968=TAS, GO:0005737=IEA, GO:0043525=IEA, GO:0045944=IMP, GO:0042789=IDA, GO:0007050=IEA, GO:0016055=IEA, GO:0090090=ISS, GO:0006355=IMP, GO:0051209=IEA, GO:2000016=IDA, GO:0003714=TAS, GO:0044324=ISS, GO:0003677=IDA, GO:0006974=TAS, GO:0043565=IEA, GO:0070059=IMP, GO:0005654=TAS, GO:0045454=IDA, GO:0043161=IDA, GO:0006987=TAS, GO:0045893=IDA, GO:0044267=TAS, GO:0001955=IEA, GO:0045892=IDA, GO:0008134=IPI} ER overload response, Wnt receptor signaling pathway, activation of signaling protein activity involved in unfolded protein response, blood vessel maturation, cell cycle arrest, cell redox homeostasis, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, mRNA transcription from RNA polymerase II promoter, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of determination of dorsal identity, negative regulation of myoblast differentiation, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription, DNA-dependent, positive regulation of interleukin-8 production, positive regulation of neuron apoptotic process, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, proteasomal ubiquitin-dependent protein catabolic process, regulation of DNA-dependent transcription in response to stress, regulation of transcription involved in anterior/posterior axis specification, regulation of transcription, DNA-dependent, release of sequestered calcium ion into cytosol, response to DNA damage stimulus, response to endoplasmic reticulum stress, response to unfolded protein cytoplasm, nucleoplasm, nucleus DNA binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity, transcription factor binding Human DDIT4 HPA UniProtKB {GO:0010741=GO_REF:0000024, GO:0001666=PMID:20166753, GO:0032007=PMID:20166753, GO:0048011=GO_REF:0000024, GO:0008283=GO_REF:0000024, GO:0072593=GO_REF:0000019, GO:0043241=GO_REF:0000019, GO:1901216=GO_REF:0000024, GO:0010801=GO_REF:0000024, GO:0005829=GO_REF:0000039, GO:0005622=GO_REF:0000054, GO:0005739=GO_REF:0000039, GO:0042771=GO_REF:0000024, GO:0071889=GO_REF:0000019, GO:0051607=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0007420=GO_REF:0000024, GO:0033137=GO_REF:0000024, GO:0030182=GO_REF:0000024, GO:0045820=GO_REF:0000019, GO:0001764=GO_REF:0000024} Q9NX09 DNA damage-inducible transcript 4 protein protein 20101115 {GO:0010741=ISS, GO:0001666=IDA, GO:0032007=IMP, GO:0048011=ISS, GO:0008283=ISS, GO:0072593=IEA, GO:0043241=IEA, GO:1901216=ISS, GO:0010801=ISS, GO:0005829=IEA, GO:0005622=IDA, GO:0005739=IEA, GO:0042771=ISS, GO:0071889=IEA, GO:0051607=IEA, GO:0005737=IDA, GO:0007420=ISS, GO:0033137=ISS, GO:0030182=ISS, GO:0045820=IEA, GO:0001764=ISS} brain development, cell proliferation, defense response to virus, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, negative regulation of TOR signaling cascade, negative regulation of glycolysis, negative regulation of intracellular protein kinase cascade, negative regulation of peptidyl-serine phosphorylation, negative regulation of peptidyl-threonine phosphorylation, neuron differentiation, neuron migration, neurotrophin TRK receptor signaling pathway, positive regulation of neuron death, protein complex disassembly, reactive oxygen species metabolic process, response to hypoxia cytoplasm, cytosol, intracellular, mitochondrion 14-3-3 protein binding Human DDIT4L UniProtKB UniProtKB {GO:0005737=GO_REF:0000024, GO:0009968=GO_REF:0000002} Q96D03 DNA damage-inducible transcript 4-like protein protein 20071012 {GO:0005737=ISS, GO:0009968=IEA} negative regulation of signal transduction cytoplasm Human UniProtKB:Q9NX09 DDN IntAct UniProtKB {GO:0005515=PMID:16751601, GO:0005737=PMID:16464232, GO:0032591=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0043204=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0042995=PMID:16464232} O94850 Dendrin protein 20130415 {GO:0005515=IPI, GO:0005737=IDA, GO:0032591=IEA, GO:0005789=IEA, GO:0043204=IEA, GO:0005634=IEA, GO:0042995=IDA} cell projection, cytoplasm, dendritic spine membrane, endoplasmic reticulum membrane, nucleus, perikaryon protein binding Human UniProtKB:Q96B97 DDO UniProtKB UniProtKB {GO:0005515=PMID:9820813, GO:0007320=GO_REF:0000019, GO:0048037=PMID:20603179, GO:0016641=GO_REF:0000002, GO:0006531=GO_REF:0000019, GO:0005102=PMID:20178365, GO:0042445=GO_REF:0000019, GO:0007625=GO_REF:0000019, GO:0003884=GO_REF:0000002, GO:0019478=PMID:20603179, GO:0005777=PMID:9820813} Q99489 D-aspartate oxidase protein 20120427 {GO:0005515=IPI, GO:0007320=IEA, GO:0048037=IDA, GO:0016641=IEA, GO:0006531=IEA, GO:0005102=IPI, GO:0042445=IEA, GO:0007625=IEA, GO:0003884=IEA, GO:0019478=IDA, GO:0005777=NAS} D-amino acid catabolic process, aspartate metabolic process, grooming behavior, hormone metabolic process, insemination peroxisome D-amino-acid oxidase activity, cofactor binding, oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor, protein binding, receptor binding Human UniProtKB:P50542 DDOST IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0004576=GO_REF:0000024, GO:0010467=Reactome:REACT_71, GO:0006614=Reactome:REACT_115902, GO:0006412=Reactome:REACT_1014, GO:0043231=PMID:9642163, GO:0043234=PMID:9642163, GO:0042110=PMID:9642163, GO:0045087=Reactome:REACT_6802, GO:0004579=PMID:15835887, GO:0005789=Reactome:REACT_22208, GO:0006486=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0006487=PMID:9642163, GO:0034097=PMID:9642163, GO:0008250=PMID:15835887, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} P39656 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit protein 20130415 {GO:0005515=IPI, GO:0004576=ISS, GO:0010467=TAS, GO:0006614=TAS, GO:0006412=TAS, GO:0043231=IDA, GO:0043234=IDA, GO:0042110=IDA, GO:0045087=TAS, GO:0004579=IC, GO:0005789=TAS, GO:0006486=ISS, GO:0016021=IEA, GO:0006487=IDA, GO:0034097=IDA, GO:0008250=TAS, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS} SRP-dependent cotranslational protein targeting to membrane, T cell activation, cellular protein metabolic process, gene expression, innate immune response, post-translational protein modification, protein N-linked glycosylation, protein N-linked glycosylation via asparagine, protein glycosylation, response to cytokine stimulus, translation endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle, oligosaccharyltransferase complex, protein complex dolichyl-diphosphooligosaccharide-protein glycotransferase activity, oligosaccharyl transferase activity, protein binding Human UniProtKB:Q86WV6 DDR1 InterPro UniProtKB {GO:0044319=PMID:12065315, GO:0005515=PMID:18190796, GO:0008285=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0005518=PMID:9659899, GO:0001558=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0043583=GO_REF:0000019, GO:0010715=PMID:12065315, GO:0046777=PMID:9659899, GO:0007155=PMID:8302582, GO:0038083=PMID:21044884, GO:0007566=GO_REF:0000019, GO:0014909=PMID:12065315, GO:0018108=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0038063=PMID:9659899, GO:0005524=GO_REF:0000002, GO:0038062=PMID:9659899, GO:0061302=PMID:12065315, GO:0004672=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0007595=GO_REF:0000037, GO:0005887=PMID:8390675, GO:0001952=GO_REF:0000019, GO:0004714=PMID:9659899, GO:0007169=GO_REF:0000002, GO:0060444=GO_REF:0000019, GO:0060749=GO_REF:0000019} Q6ZNR9 Epithelial discoidin domain-containing receptor 1 protein 20130413 {GO:0044319=IMP, GO:0005515=IPI, GO:0008285=IEA, GO:0005886=IEA, GO:0005518=IDA, GO:0001558=IEA, GO:0046872=IEA, GO:0043583=IEA, GO:0010715=IMP, GO:0046777=IDA, GO:0007155=TAS, GO:0038083=IDA, GO:0007566=IEA, GO:0014909=IMP, GO:0018108=IEA, GO:0005576=IEA, GO:0038063=IDA, GO:0005524=IEA, GO:0038062=IDA, GO:0061302=IMP, GO:0004672=IEA, GO:0016020=IEA, GO:0007595=IEA, GO:0005887=TAS, GO:0001952=IEA, GO:0004714=TAS, GO:0007169=IEA, GO:0060444=IEA, GO:0060749=IEA} branching involved in mammary gland duct morphogenesis, cell adhesion, collagen-activated tyrosine kinase receptor signaling pathway, ear development, embryo implantation, lactation, mammary gland alveolus development, negative regulation of cell proliferation, peptidyl-tyrosine autophosphorylation, peptidyl-tyrosine phosphorylation, protein autophosphorylation, regulation of cell growth, regulation of cell-matrix adhesion, regulation of extracellular matrix disassembly, smooth muscle cell migration, smooth muscle cell-matrix adhesion, transmembrane receptor protein tyrosine kinase signaling pathway, wound healing, spreading of cells extracellular region, integral to plasma membrane, membrane, plasma membrane ATP binding, collagen binding, metal ion binding, protein binding, protein kinase activity, protein tyrosine kinase collagen receptor activity, transmembrane receptor protein tyrosine kinase activity Human InterPro:IPR000719 DDR2 ENSEMBL UniProtKB {GO:0005515=PMID:22939624, GO:0030500=PMID:20564243, GO:0003416=GO_REF:0000019, GO:0005518=PMID:20004161, GO:0018108=PMID:20004161, GO:0048146=GO_REF:0000019, GO:0038063=PMID:16186108, GO:0031214=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0035988=GO_REF:0000019, GO:0038062=GO_REF:0000019, GO:0010715=PMID:16626936, GO:0045669=PMID:20564243, GO:0007165=PMID:9659899, GO:0051091=PMID:20564243, GO:0046777=PMID:16186108, GO:0010763=GO_REF:0000019, GO:0001503=GO_REF:0000037, GO:0005887=PMID:9659899, GO:0030199=GO_REF:0000019, GO:0045860=PMID:20564243, GO:0090091=GO_REF:0000019, GO:0007155=GO_REF:0000002, GO:0004714=PMID:20004161} Q5T245 Discoidin domain-containing receptor 2 protein 20130413 {GO:0005515=IPI, GO:0030500=IMP, GO:0003416=IEA, GO:0005518=IDA, GO:0018108=IDA, GO:0048146=IEA, GO:0038063=IDA, GO:0031214=IEA, GO:0005524=IEA, GO:0035988=IEA, GO:0038062=IEA, GO:0010715=TAS, GO:0045669=IMP, GO:0007165=TAS, GO:0051091=IMP, GO:0046777=IDA, GO:0010763=IEA, GO:0001503=IEA, GO:0005887=TAS, GO:0030199=IEA, GO:0045860=IMP, GO:0090091=IEA, GO:0007155=IEA, GO:0004714=IDA} biomineral tissue development, cell adhesion, chondrocyte proliferation, collagen fibril organization, collagen-activated tyrosine kinase receptor signaling pathway, endochondral bone growth, ossification, peptidyl-tyrosine phosphorylation, positive regulation of extracellular matrix disassembly, positive regulation of fibroblast migration, positive regulation of fibroblast proliferation, positive regulation of osteoblast differentiation, positive regulation of protein kinase activity, positive regulation of sequence-specific DNA binding transcription factor activity, protein autophosphorylation, regulation of bone mineralization, regulation of extracellular matrix disassembly, signal transduction integral to plasma membrane ATP binding, collagen binding, protein binding, protein tyrosine kinase collagen receptor activity, transmembrane receptor protein tyrosine kinase activity Human Ensembl:ENSMUSP00000129624 DDRGK1 UniProtKB UniProtKB {GO:0005515=PMID:20018847, GO:0005783=PMID:20018847} Q96HY6 DDRGK domain-containing protein 1 protein 20100204 {GO:0005515=IPI, GO:0005783=IDA} endoplasmic reticulum protein binding Human UniProtKB:Q9Y3C8 DDT PINC UniProtKB {GO:0005737=GO_REF:0000039, GO:0004167=PMID:9480844, GO:0033981=GO_REF:0000003, GO:0042438=GO_REF:0000037} P30046 D-dopachrome decarboxylase protein 20030904 {GO:0005737=IEA, GO:0004167=TAS, GO:0033981=IEA, GO:0042438=IEA} melanin biosynthetic process cytoplasm D-dopachrome decarboxylase activity, dopachrome isomerase activity Human DDTL UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0016829=GO_REF:0000037} A6NHG4 D-dopachrome decarboxylase-like protein protein 20130413 {GO:0005737=IEA, GO:0016829=IEA} cytoplasm lyase activity Human UniProtKB-SubCell:SL-0086 DDX1 GOC UniProtKB {GO:0005515=PMID:18335541, GO:0003725=GO_REF:0000019, GO:0003724=PMID:7689221, GO:0090305=PMID:18710941, GO:0010494=PMID:18335541, GO:0005634=GO_REF:0000052, GO:0071920=PMID:11598190, GO:0072669=PMID:21311021, GO:0006302=PMID:18710941, GO:0005737=GO_REF:0000052, GO:0004527=GO_REF:0000037, GO:0008143=PMID:12183465, GO:0032508=PMID:18710941, GO:0003712=PMID:19058135, GO:0008026=PMID:12183465, GO:0000245=PMID:7689221, GO:0006355=GO_REF:0000037, GO:0033677=PMID:18710941, GO:0005730=GO_REF:0000052, GO:0007275=PMID:7689221, GO:0009615=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0004518=PMID:18710941, GO:0030529=PMID:18809582, GO:0003682=PMID:19058135, GO:0006446=PMID:7689221, GO:0043330=GO_REF:0000019} Q92499 ATP-dependent RNA helicase DDX1 protein 20130413 {GO:0005515=IPI, GO:0003725=IEA, GO:0003724=TAS, GO:0090305=IDA, GO:0010494=IDA, GO:0005634=IDA, GO:0071920=IDA, GO:0072669=IDA, GO:0006302=IDA, GO:0005737=IDA, GO:0004527=IEA, GO:0008143=IDA, GO:0032508=IDA, GO:0003712=IDA, GO:0008026=IDA, GO:0000245=NAS, GO:0006355=IEA, GO:0033677=IDA, GO:0005730=IDA, GO:0007275=IEP, GO:0009615=IEA, GO:0005524=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0004518=IDA, GO:0030529=IDA, GO:0003682=IDA, GO:0006446=NAS, GO:0043330=IEA} DNA duplex unwinding, double-strand break repair, multicellular organismal development, nucleic acid phosphodiester bond hydrolysis, regulation of transcription, DNA-dependent, regulation of translational initiation, response to exogenous dsRNA, response to virus, spliceosomal complex assembly, transcription, DNA-dependent cleavage body, cytoplasm, cytoplasmic stress granule, nucleolus, nucleus, ribonucleoprotein complex, tRNA-splicing ligase complex ATP binding, ATP-dependent helicase activity, DNA binding, DNA/RNA helicase activity, RNA helicase activity, chromatin binding, double-stranded RNA binding, exonuclease activity, nuclease activity, poly(A) RNA binding, protein binding, transcription cofactor activity Human DDX10 PINC UniProtKB {GO:0008026=GO_REF:0000002, GO:0003724=PMID:8660968, GO:0003723=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q13206 Probable ATP-dependent RNA helicase DDX10 protein 20030904 {GO:0008026=IEA, GO:0003724=TAS, GO:0003723=IEA, GO:0005524=IEA} ATP binding, ATP-dependent helicase activity, RNA binding, RNA helicase activity Human DDX11 Reactome UniProtKB {GO:0005515=PMID:17189189, GO:0000790=PMID:17105772, GO:0008284=PMID:9013641, GO:0016817=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005634=PMID:17189189, GO:0046872=GO_REF:0000037, GO:0030968=Reactome:REACT_18356, GO:0000084=PMID:9013641, GO:0004003=GO_REF:0000002, GO:0000086=PMID:9013641, GO:0032508=GO_REF:0000002, GO:0008094=PMID:18499658, GO:0008026=GO_REF:0000002, GO:0051539=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0004386=PMID:18499658, GO:0030496=PMID:17105772, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0003678=PMID:9013641, GO:0000922=PMID:17105772, GO:0000070=PMID:9013641, GO:0019048=GO_REF:0000037, GO:0007062=PMID:17105772, GO:0005654=Reactome:REACT_116074, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015} Q96FC9 Probable ATP-dependent RNA helicase DDX11 protein 20130301 {GO:0005515=IPI, GO:0000790=IDA, GO:0008284=TAS, GO:0016817=IEA, GO:0003723=IEA, GO:0005634=IDA, GO:0046872=IEA, GO:0030968=TAS, GO:0000084=TAS, GO:0004003=IEA, GO:0000086=TAS, GO:0032508=IEA, GO:0008094=IDA, GO:0008026=IEA, GO:0051539=IEA, GO:0005730=IEA, GO:0004386=IDA, GO:0030496=IDA, GO:0003676=IEA, GO:0005524=IEA, GO:0003677=IEA, GO:0003678=TAS, GO:0000922=IDA, GO:0000070=TAS, GO:0019048=IEA, GO:0007062=IDA, GO:0005654=TAS, GO:0006987=TAS, GO:0044267=TAS} DNA duplex unwinding, G2/M transition of mitotic cell cycle, S phase of mitotic cell cycle, activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, mitotic sister chromatid segregation, positive regulation of cell proliferation, sister chromatid cohesion, virus-host interaction midbody, nuclear chromatin, nucleolus, nucleoplasm, nucleus, spindle pole 4 iron, 4 sulfur cluster binding, ATP binding, ATP-dependent DNA helicase activity, ATP-dependent helicase activity, DNA binding, DNA helicase activity, DNA-dependent ATPase activity, RNA binding, helicase activity, hydrolase activity, acting on acid anhydrides, metal ion binding, nucleic acid binding, protein binding Human DDX17 IntAct UniProtKB {GO:0005515=PMID:22266867, GO:0008026=GO_REF:0000002, GO:0006396=PMID:8871553, GO:0003724=PMID:8871553, GO:0003723=GO_REF:0000037, GO:0003713=PMID:11250900, GO:0030331=PMID:11250900, GO:0005730=GO_REF:0000039, GO:0005634=PMID:11250900, GO:0003676=GO_REF:0000002, GO:0009791=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0008186=PMID:8871553, GO:0045944=PMID:11250900, GO:0033148=PMID:11250900, GO:2001014=PMID:17011493, GO:0072358=GO_REF:0000019} Q92841 Probable ATP-dependent RNA helicase DDX17 protein 20130415 {GO:0005515=IPI, GO:0008026=IEA, GO:0006396=TAS, GO:0003724=TAS, GO:0003723=IEA, GO:0003713=IDA, GO:0030331=IDA, GO:0005730=IEA, GO:0005634=IDA, GO:0003676=IEA, GO:0009791=IEA, GO:0005524=IEA, GO:0006351=IEA, GO:0008186=TAS, GO:0045944=IDA, GO:0033148=IDA, GO:2001014=IMP, GO:0072358=IEA} RNA processing, cardiovascular system development, positive regulation of intracellular estrogen receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, post-embryonic development, regulation of skeletal muscle cell differentiation, transcription, DNA-dependent nucleolus, nucleus ATP binding, ATP-dependent helicase activity, RNA binding, RNA helicase activity, RNA-dependent ATPase activity, estrogen receptor binding, nucleic acid binding, protein binding, transcription coactivator activity Human UniProtKB:O94916 DDX18 PINC UniProtKB {GO:0004004=PMID:8861962, GO:0005515=PMID:16963496, GO:0008026=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005730=PMID:16963496, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q9NVP1 ATP-dependent RNA helicase DDX18 protein 20030904 {GO:0004004=TAS, GO:0005515=IPI, GO:0008026=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0003676=IEA, GO:0005524=IEA} nucleolus ATP binding, ATP-dependent RNA helicase activity, ATP-dependent helicase activity, RNA binding, nucleic acid binding, protein binding Human DDX19A UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0031965=GO_REF:0000039, GO:0005737=GO_REF:0000039, GO:0005643=GO_REF:0000039, GO:0003723=GO_REF:0000037, GO:0051028=GO_REF:0000037, GO:0006917=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0010043=GO_REF:0000019, GO:0005524=GO_REF:0000037} Q9NUU7 ATP-dependent RNA helicase DDX19A protein 20130413 {GO:0008026=IEA, GO:0031965=IEA, GO:0005737=IEA, GO:0005643=IEA, GO:0003723=IEA, GO:0051028=IEA, GO:0006917=IEA, GO:0015031=IEA, GO:0003676=IEA, GO:0010043=IEA, GO:0005524=IEA} induction of apoptosis, mRNA transport, protein transport, response to zinc ion cytoplasm, nuclear membrane, nuclear pore ATP binding, ATP-dependent helicase activity, RNA binding, nucleic acid binding Human UniProtKB-SubCell:SL-0182 DDX19B LIFEdb UniProtKB {GO:0008026=GO_REF:0000002, GO:0031965=GO_REF:0000039, GO:0005737=GO_REF:0000039, GO:0006406=PMID:10428971, GO:0005643=GO_REF:0000039, GO:0003723=GO_REF:0000037, GO:0004386=PMID:10428971, GO:0005635=GO_REF:0000054, GO:0015031=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q9UMR2 ATP-dependent RNA helicase DDX19B protein 20100607 {GO:0008026=IEA, GO:0031965=IEA, GO:0005737=IEA, GO:0006406=TAS, GO:0005643=IEA, GO:0003723=IEA, GO:0004386=TAS, GO:0005635=IDA, GO:0015031=IEA, GO:0003676=IEA, GO:0005524=IEA} mRNA export from nucleus, protein transport cytoplasm, nuclear envelope, nuclear membrane, nuclear pore ATP binding, ATP-dependent helicase activity, RNA binding, helicase activity, nucleic acid binding Human DDX20 HPA UniProtKB {GO:0000244=PMID:10601333, GO:0008026=GO_REF:0000002, GO:0005515=PMID:11714716, GO:0010467=Reactome:REACT_71, GO:0006396=PMID:10601333, GO:0015030=GO_REF:0000039, GO:0043065=GO_REF:0000024, GO:0016070=Reactome:REACT_21257, GO:0005634=GO_REF:0000052, GO:0034660=Reactome:REACT_11052, GO:0000122=GO_REF:0000019, GO:0006917=GO_REF:0000019, GO:0000387=Reactome:REACT_11066, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0005829=Reactome:REACT_10041, GO:0004004=PMID:10383418, GO:0005737=GO_REF:0000052, GO:0017053=GO_REF:0000019, GO:0005654=Reactome:REACT_10010, GO:0005681=GO_REF:0000037, GO:0005856=PMID:10383418} Q9UHI6 Probable ATP-dependent RNA helicase DDX20 protein 20080205 {GO:0000244=TAS, GO:0008026=IEA, GO:0005515=IPI, GO:0010467=TAS, GO:0006396=TAS, GO:0015030=IEA, GO:0043065=ISS, GO:0016070=TAS, GO:0005634=IDA, GO:0034660=TAS, GO:0000122=IEA, GO:0006917=IEA, GO:0000387=TAS, GO:0003676=IEA, GO:0005524=IEA, GO:0003677=IEA, GO:0005829=TAS, GO:0004004=TAS, GO:0005737=IDA, GO:0017053=IEA, GO:0005654=TAS, GO:0005681=IEA, GO:0005856=TAS} RNA metabolic process, RNA processing, assembly of spliceosomal tri-snRNP, gene expression, induction of apoptosis, ncRNA metabolic process, negative regulation of transcription from RNA polymerase II promoter, positive regulation of apoptotic process, spliceosomal snRNP assembly Cajal body, cytoplasm, cytoskeleton, cytosol, nucleoplasm, nucleus, spliceosomal complex, transcriptional repressor complex ATP binding, ATP-dependent RNA helicase activity, ATP-dependent helicase activity, DNA binding, nucleic acid binding, protein binding Human DDX21 HPA UniProtKB {GO:0004004=PMID:8614622, GO:0003725=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0009615=GO_REF:0000019, GO:0043330=GO_REF:0000019, GO:0005524=GO_REF:0000037} Q9NR30 Nucleolar RNA helicase 2 protein 20110516 {GO:0004004=TAS, GO:0003725=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0009615=IEA, GO:0043330=IEA, GO:0005524=IEA} response to exogenous dsRNA, response to virus nucleolus, nucleus ATP binding, ATP-dependent RNA helicase activity, double-stranded RNA binding Human DDX23 HPA UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0008026=PMID:9539711, GO:0005515=PMID:20858735, GO:0010467=Reactome:REACT_71, GO:0005886=GO_REF:0000052, GO:0004386=GO_REF:0000038, GO:0005730=GO_REF:0000052, GO:0000354=PMID:9539711, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0071013=PMID:11991638, GO:0005524=GO_REF:0000037, GO:0005739=GO_REF:0000052, GO:0004004=PMID:9409622, GO:0000398=Reactome:REACT_1753, GO:0000375=PMID:9409622, GO:0005654=Reactome:REACT_2241, GO:0005682=PMID:9539711} Q9BUQ8 Probable ATP-dependent RNA helicase DDX23 protein 20110516 {GO:0008380=TAS, GO:0008026=IDA, GO:0005515=IPI, GO:0010467=TAS, GO:0005886=IDA, GO:0004386=IEA, GO:0005730=IDA, GO:0000354=IC, GO:0005634=IDA, GO:0003676=IEA, GO:0071013=IDA, GO:0005524=IEA, GO:0005739=IDA, GO:0004004=TAS, GO:0000398=TAS, GO:0000375=TAS, GO:0005654=TAS, GO:0005682=IDA} RNA splicing, RNA splicing, via transesterification reactions, cis assembly of pre-catalytic spliceosome, gene expression, mRNA splicing, via spliceosome U5 snRNP, catalytic step 2 spliceosome, mitochondrion, nucleolus, nucleoplasm, nucleus, plasma membrane ATP binding, ATP-dependent RNA helicase activity, ATP-dependent helicase activity, helicase activity, nucleic acid binding, protein binding Human DDX24 HPA UniProtKB {GO:0004004=GO_REF:0000029, GO:0008026=GO_REF:0000002, GO:0003724=PMID:10936056, GO:0005737=GO_REF:0000052, GO:0016070=PMID:10936056, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q9GZR7 ATP-dependent RNA helicase DDX24 protein 20080205 {GO:0004004=NAS, GO:0008026=IEA, GO:0003724=NAS, GO:0005737=IDA, GO:0016070=NAS, GO:0003723=IEA, GO:0005730=IDA, GO:0003676=IEA, GO:0005524=IEA} RNA metabolic process cytoplasm, nucleolus ATP binding, ATP-dependent RNA helicase activity, ATP-dependent helicase activity, RNA binding, RNA helicase activity, nucleic acid binding Human DDX26B null null {} null null null null {} null null null DDX27 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q96GQ7 Probable ATP-dependent RNA helicase DDX27 protein 20130413 {GO:0008026=IEA, GO:0005634=IEA, GO:0003676=IEA, GO:0005524=IEA} nucleus ATP binding, ATP-dependent helicase activity, nucleic acid binding Human UniProtKB-SubCell:SL-0191 DDX28 HPA UniProtKB {GO:0042645=PMID:18063578, GO:0005739=GO_REF:0000052, GO:0008026=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037} Q9NUL7 Probable ATP-dependent RNA helicase DDX28 protein 20111111 {GO:0042645=IDA, GO:0005739=IDA, GO:0008026=IEA, GO:0005737=IDA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005524=IEA} cytoplasm, mitochondrial nucleoid, mitochondrion, nucleolus, nucleus ATP binding, ATP-dependent helicase activity, RNA binding Human DDX31 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0004386=GO_REF:0000038, GO:0005524=GO_REF:0000037} Q9H8H2 Probable ATP-dependent RNA helicase DDX31 protein 20130413 {GO:0008026=IEA, GO:0003723=IEA, GO:0005730=IEA, GO:0004386=IEA, GO:0005524=IEA} nucleolus ATP binding, ATP-dependent helicase activity, RNA binding, helicase activity Human UniProtKB-SubCell:SL-0188 DDX39A InterPro UniProtKB {GO:0005515=PMID:21859714, GO:0008026=GO_REF:0000002, GO:0005737=PMID:21859714, GO:0006406=PMID:15047853, GO:0000398=PMID:15047853, GO:0005634=PMID:21859714, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000002} Q8N5M0 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39, isoform CRA_c protein 20130413 {GO:0005515=IPI, GO:0008026=IEA, GO:0005737=IDA, GO:0006406=IGI, GO:0000398=IGI, GO:0005634=IDA, GO:0003676=IEA, GO:0005524=IEA} mRNA export from nucleus, mRNA splicing, via spliceosome cytoplasm, nucleus ATP binding, ATP-dependent helicase activity, nucleic acid binding, protein binding Human InterPro:IPR011545 DDX39B UniProtKB UniProtKB {GO:0008380=PMID:18593880, GO:0008026=GO_REF:0000002, GO:0005515=PMID:21859714, GO:0000245=PMID:18593880, GO:0043008=PMID:18593880, GO:0000346=PMID:15998806, GO:0004386=GO_REF:0000002, GO:0030621=PMID:18593880, GO:0005634=PMID:21859714, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000038, GO:0046784=PMID:18974867, GO:0008186=PMID:17562711, GO:0004004=PMID:18593880, GO:0005737=PMID:21859714, GO:0006406=PMID:17190602, GO:0016607=GO_REF:0000039, GO:0000398=PMID:15047853, GO:0010501=PMID:18593880, GO:0005681=PMID:18593880, GO:0017070=PMID:18593880, GO:0005687=PMID:18593880, GO:0005688=PMID:18593880} Q5STU3 Spliceosome RNA helicase DDX39B protein 20130413 {GO:0008380=IDA, GO:0008026=IEA, GO:0005515=IPI, GO:0000245=IDA, GO:0043008=IDA, GO:0000346=IDA, GO:0004386=IEA, GO:0030621=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0005524=IEA, GO:0046784=IDA, GO:0008186=IDA, GO:0004004=IDA, GO:0005737=IDA, GO:0006406=IDA, GO:0016607=IEA, GO:0000398=IGI, GO:0010501=IDA, GO:0005681=IDA, GO:0017070=IDA, GO:0005687=IDA, GO:0005688=IDA} RNA secondary structure unwinding, RNA splicing, intronless viral mRNA export from host nucleus, mRNA export from nucleus, mRNA splicing, via spliceosome, spliceosomal complex assembly U4 snRNP, U6 snRNP, cytoplasm, nuclear speck, nucleus, spliceosomal complex, transcription export complex ATP binding, ATP-dependent RNA helicase activity, ATP-dependent helicase activity, ATP-dependent protein binding, RNA-dependent ATPase activity, U4 snRNA binding, U6 snRNA binding, helicase activity, nucleic acid binding, protein binding Human UniProtKB-KW:KW-0067 DDX3X GOC UniProtKB {GO:0005515=PMID:22323517, GO:0017148=PMID:17667941, GO:0048027=PMID:22872150, GO:0030308=PMID:16818630, GO:0030307=PMID:20837705, GO:0007243=PMID:18636090, GO:0043024=PMID:22323517, GO:0032728=PMID:18583960, GO:0005852=PMID:18628297, GO:0042256=PMID:22323517, GO:0071470=PMID:21883093, GO:2001243=PMID:21883093, GO:0043280=PMID:16301996, GO:0034063=PMID:21883093, GO:0010501=PMID:22872150, GO:0045087=PMID:18583960, GO:0071243=PMID:21883093, GO:0008134=PMID:16818630, GO:0008625=PMID:18846110, GO:0035613=PMID:22872150, GO:0006200=PMID:21589879, GO:1900087=PMID:20837705, GO:0010494=PMID:21883093, GO:0003723=PMID:21589879, GO:0071651=PMID:18583960, GO:0005741=GO_REF:0000039, GO:0005634=PMID:10329544, GO:0004004=PMID:21589879, GO:0005737=GO_REF:0000052, GO:0004003=PMID:21589879, GO:0007059=PMID:21730191, GO:0031333=PMID:17667941, GO:0045944=PMID:18583960, GO:0008143=PMID:18596238, GO:0045948=PMID:20837705, GO:0043154=PMID:18846110, GO:0016887=PMID:21589879, GO:0043066=PMID:18846110, GO:0043065=PMID:16301996, GO:0004386=GO_REF:0000038, GO:0045727=PMID:18596238, GO:0009615=PMID:18636090, GO:0005524=GO_REF:0000037, GO:0003677=PMID:21589879, GO:0097193=PMID:16301996, GO:0006351=GO_REF:0000037, GO:0016607=GO_REF:0000039, GO:0022627=PMID:18596238, GO:0019048=GO_REF:0000037, GO:0008190=PMID:17667941, GO:0031369=PMID:22323517} O00571 ATP-dependent RNA helicase DDX3X protein 20130413 {GO:0005515=IPI, GO:0017148=IMP, GO:0048027=IDA, GO:0030308=IDA, GO:0030307=IMP, GO:0007243=IDA, GO:0043024=IDA, GO:0032728=TAS, GO:0005852=IDA, GO:0042256=IMP, GO:0071470=IDA, GO:2001243=IMP, GO:0043280=IMP, GO:0034063=IDA, GO:0010501=IDA, GO:0045087=IMP, GO:0071243=IDA, GO:0008134=IDA, GO:0008625=IMP, GO:0035613=IDA, GO:0006200=IDA, GO:1900087=IMP, GO:0010494=IDA, GO:0003723=IDA, GO:0071651=TAS, GO:0005741=IEA, GO:0005634=IDA, GO:0004004=IDA, GO:0005737=IDA, GO:0004003=IDA, GO:0007059=IMP, GO:0031333=IDA, GO:0045944=IMP, GO:0008143=IDA, GO:0045948=IMP, GO:0043154=IMP, GO:0016887=IDA, GO:0043066=IMP, GO:0043065=IMP, GO:0004386=IEA, GO:0045727=IDA, GO:0009615=IDA, GO:0005524=IEA, GO:0003677=IDA, GO:0097193=IMP, GO:0006351=IEA, GO:0016607=IEA, GO:0022627=IDA, GO:0019048=IEA, GO:0008190=IDA, GO:0031369=IDA} ATP catabolic process, RNA secondary structure unwinding, cellular response to arsenic-containing substance, cellular response to osmotic stress, chromosome segregation, extrinsic apoptotic signaling pathway via death domain receptors, innate immune response, intracellular protein kinase cascade, intrinsic apoptotic signaling pathway, mature ribosome assembly, negative regulation of apoptotic process, negative regulation of cell growth, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of intrinsic apoptotic signaling pathway, negative regulation of protein complex assembly, negative regulation of translation, positive regulation of G1/S transition of mitotic cell cycle, positive regulation of apoptotic process, positive regulation of cell growth, positive regulation of chemokine (C-C motif) ligand 5 production, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of interferon-beta production, positive regulation of transcription from RNA polymerase II promoter, positive regulation of translation, positive regulation of translational initiation, response to virus, stress granule assembly, transcription, DNA-dependent, virus-host interaction cytoplasm, cytoplasmic stress granule, cytosolic small ribosomal subunit, eukaryotic translation initiation factor 3 complex, mitochondrial outer membrane, nuclear speck, nucleus ATP binding, ATP-dependent DNA helicase activity, ATP-dependent RNA helicase activity, ATPase activity, DNA binding, RNA binding, RNA stem-loop binding, eukaryotic initiation factor 4E binding, helicase activity, mRNA 5'-UTR binding, poly(A) RNA binding, protein binding, ribosomal small subunit binding, transcription factor binding, translation initiation factor binding Human DDX3Y HPA UniProtKB {GO:0008026=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037} O15523 ATP-dependent RNA helicase DDX3Y protein 20101115 {GO:0008026=IEA, GO:0005737=IDA, GO:0003723=IEA, GO:0005634=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0005524=IEA} cytoplasm, nucleus ATP binding, ATP-dependent helicase activity, DNA binding, RNA binding, nucleic acid binding Human DDX4 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0048471=GO_REF:0000039, GO:0000237=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0030317=PMID:21034600, GO:0007283=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0032880=GO_REF:0000019, GO:0033391=GO_REF:0000019, GO:0005737=PMID:21421998, GO:0071546=GO_REF:0000024, GO:0071547=GO_REF:0000024, GO:0007141=GO_REF:0000019} Q9NQI0 Probable ATP-dependent RNA helicase DDX4 protein 20110412 {GO:0008026=IEA, GO:0048471=IEA, GO:0000237=IEA, GO:0005634=IEA, GO:0007275=IEA, GO:0030317=IMP, GO:0007283=IEA, GO:0003676=IEA, GO:0005524=IEA, GO:0032880=IEA, GO:0033391=IEA, GO:0005737=IDA, GO:0071546=ISS, GO:0071547=ISS, GO:0007141=IEA} leptotene, male meiosis I, multicellular organismal development, regulation of protein localization, sperm motility, spermatogenesis chromatoid body, cytoplasm, nucleus, perinuclear region of cytoplasm, pi-body, piP-body ATP binding, ATP-dependent helicase activity, nucleic acid binding Human DDX41 HPA UniProtKB {GO:0008026=GO_REF:0000002, GO:0006396=PMID:10607561, GO:0035458=GO_REF:0000019, GO:0005783=GO_REF:0000019, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0006915=PMID:10607561, GO:0007275=PMID:10607561, GO:0005634=GO_REF:0000052, GO:0071013=PMID:11991638, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000019, GO:0051607=GO_REF:0000019, GO:0000398=PMID:11991638, GO:0045944=GO_REF:0000019, GO:0008270=GO_REF:0000002} Q9UJV9 Probable ATP-dependent RNA helicase DDX41 protein 20101115 {GO:0008026=IEA, GO:0006396=TAS, GO:0035458=IEA, GO:0005783=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0006915=TAS, GO:0007275=TAS, GO:0005634=IDA, GO:0071013=IDA, GO:0003676=IEA, GO:0005524=IEA, GO:0003677=IEA, GO:0051607=IEA, GO:0000398=IC, GO:0045944=IEA, GO:0008270=IEA} RNA processing, apoptotic process, cellular response to interferon-beta, defense response to virus, mRNA splicing, via spliceosome, multicellular organismal development, positive regulation of transcription from RNA polymerase II promoter catalytic step 2 spliceosome, endoplasmic reticulum, nucleolus, nucleus ATP binding, ATP-dependent helicase activity, DNA binding, RNA binding, nucleic acid binding, zinc ion binding NOT Human DDX42 HPA UniProtKB {GO:0005515=PMID:19377511, GO:0008026=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0008104=PMID:19377511, GO:0015030=GO_REF:0000039, GO:0016607=GO_REF:0000039, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037} Q86XP3 ATP-dependent RNA helicase DDX42 protein 20101115 {GO:0005515=IPI, GO:0008026=IEA, GO:0005737=IDA, GO:0008104=IDA, GO:0015030=IEA, GO:0016607=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005524=IEA} protein localization Cajal body, cytoplasm, nuclear speck, nucleolus, nucleus ATP binding, ATP-dependent helicase activity, RNA binding, protein binding Human DDX43 LIFEdb UniProtKB {GO:0005622=GO_REF:0000054, GO:0004004=PMID:10919659, GO:0003723=GO_REF:0000037, GO:0004386=GO_REF:0000038, GO:0005524=GO_REF:0000037} Q9NXZ2 Probable ATP-dependent RNA helicase DDX43 protein 20100607 {GO:0005622=IDA, GO:0004004=TAS, GO:0003723=IEA, GO:0004386=IEA, GO:0005524=IEA} intracellular ATP binding, ATP-dependent RNA helicase activity, RNA binding, helicase activity Human DDX46 HPA UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0008026=GO_REF:0000002, GO:0015030=GO_REF:0000039, GO:0016607=GO_REF:0000039, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q7L014 Probable ATP-dependent RNA helicase DDX46 protein 20110516 {GO:0008380=IEA, GO:0006397=IEA, GO:0008026=IEA, GO:0015030=IEA, GO:0016607=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0005524=IEA} RNA splicing, mRNA processing Cajal body, nuclear speck, nucleolus, nucleus ATP binding, ATP-dependent helicase activity, RNA binding, nucleic acid binding Human DDX47 HPA UniProtKB {GO:0008380=PMID:16963496, GO:0005515=PMID:15977068, GO:0006397=GO_REF:0000037, GO:0008026=GO_REF:0000002, GO:0006364=PMID:16963496, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0006915=PMID:15977068, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q9H0S4 Probable ATP-dependent RNA helicase DDX47 protein 20090616 {GO:0008380=IMP, GO:0005515=IPI, GO:0006397=IEA, GO:0008026=IEA, GO:0006364=IMP, GO:0003723=IEA, GO:0005730=IDA, GO:0006915=IDA, GO:0003676=IEA, GO:0005524=IEA} RNA splicing, apoptotic process, mRNA processing, rRNA processing nucleolus ATP binding, ATP-dependent helicase activity, RNA binding, nucleic acid binding, protein binding Human DDX49 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q9Y6V7 Probable ATP-dependent RNA helicase DDX49 protein 20130413 {GO:0008026=IEA, GO:0003723=IEA, GO:0003676=IEA, GO:0005524=IEA} ATP binding, ATP-dependent helicase activity, RNA binding, nucleic acid binding Human UniProtKB-KW:KW-0067 DDX5 HPA UniProtKB {GO:0005515=PMID:22266867, GO:0005516=GO_REF:0000019, GO:0003724=PMID:21343338, GO:0045069=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0050681=PMID:18829551, GO:0071013=PMID:11991638, GO:0004004=GO_REF:0000019, GO:0000381=PMID:21343338, GO:0045944=PMID:10409727, GO:2001014=GO_REF:0000024, GO:0036002=PMID:21343338, GO:0003712=GO_REF:0000019, GO:0008026=GO_REF:0000002, GO:0030331=PMID:10409727, GO:0003713=PMID:10409727, GO:0060765=PMID:18829551, GO:0005730=GO_REF:0000052, GO:0000122=PMID:15298701, GO:0003676=GO_REF:0000002, GO:0001701=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0045667=GO_REF:0000024, GO:0072332=PMID:15660129, GO:0000398=PMID:11991638, GO:0030529=PMID:18809582, GO:0043517=PMID:15660129, GO:0007623=GO_REF:0000019, GO:0016049=PMID:2451786, GO:0033148=PMID:11250900, GO:0045893=GO_REF:0000019, GO:0019899=GO_REF:0000019, GO:0048306=GO_REF:0000019} P17844 Probable ATP-dependent RNA helicase DDX5 protein 20101115 {GO:0005515=IPI, GO:0005516=IEA, GO:0003724=IMP, GO:0045069=IEA, GO:0005634=IDA, GO:0050681=IDA, GO:0071013=IDA, GO:0004004=IEA, GO:0000381=IDA, GO:0045944=IDA, GO:2001014=ISS, GO:0036002=IDA, GO:0003712=IEA, GO:0008026=IEA, GO:0030331=IDA, GO:0003713=IDA, GO:0060765=IMP, GO:0005730=IDA, GO:0000122=IDA, GO:0003676=IEA, GO:0001701=IEA, GO:0005524=IEA, GO:0006351=IEA, GO:0045667=ISS, GO:0072332=IMP, GO:0000398=IC, GO:0030529=IDA, GO:0043517=IMP, GO:0007623=IEA, GO:0016049=NAS, GO:0033148=IDA, GO:0045893=IEA, GO:0019899=IEA, GO:0048306=IEA} cell growth, circadian rhythm, in utero embryonic development, intrinsic apoptotic signaling pathway by p53 class mediator, mRNA splicing, via spliceosome, negative regulation of transcription from RNA polymerase II promoter, positive regulation of DNA damage response, signal transduction by p53 class mediator, positive regulation of intracellular estrogen receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of alternative mRNA splicing, via spliceosome, regulation of androgen receptor signaling pathway, regulation of osteoblast differentiation, regulation of skeletal muscle cell differentiation, regulation of viral genome replication, transcription, DNA-dependent catalytic step 2 spliceosome, nucleolus, nucleus, ribonucleoprotein complex ATP binding, ATP-dependent RNA helicase activity, ATP-dependent helicase activity, RNA helicase activity, androgen receptor binding, calcium-dependent protein binding, calmodulin binding, enzyme binding, estrogen receptor binding, nucleic acid binding, pre-mRNA binding, protein binding, transcription coactivator activity, transcription cofactor activity NOT Human DDX50 HPA UniProtKB {GO:0008026=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005524=GO_REF:0000037} Q9BQ39 ATP-dependent RNA helicase DDX50 protein 20110516 {GO:0008026=IEA, GO:0005886=IDA, GO:0003723=IEA, GO:0005730=IDA, GO:0005524=IEA} nucleolus, plasma membrane ATP binding, ATP-dependent helicase activity, RNA binding Human DDX51 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0006364=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0005524=GO_REF:0000037} Q8N8A6 ATP-dependent RNA helicase DDX51 protein 20130413 {GO:0008026=IEA, GO:0006364=IEA, GO:0003723=IEA, GO:0005730=IEA, GO:0005524=IEA} rRNA processing nucleolus ATP binding, ATP-dependent helicase activity, RNA binding Human UniProtKB-SubCell:SL-0188 DDX52 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0004386=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q9Y2R4 Probable ATP-dependent RNA helicase DDX52 protein 20130413 {GO:0008026=IEA, GO:0003723=IEA, GO:0005730=IEA, GO:0004386=IEA, GO:0003676=IEA, GO:0005524=IEA} nucleolus ATP binding, ATP-dependent helicase activity, RNA binding, helicase activity, nucleic acid binding Human UniProtKB-SubCell:SL-0188 DDX53 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0005524=GO_REF:0000037} Q86TM3 Probable ATP-dependent RNA helicase DDX53 protein 20130413 {GO:0008026=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0005524=IEA} nucleus ATP binding, ATP-dependent helicase activity, RNA binding Human UniProtKB-SubCell:SL-0191 DDX54 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0006396=PMID:12466272, GO:0006355=GO_REF:0000037, GO:0016070=PMID:12466272, GO:0003723=GO_REF:0000037, GO:0003714=PMID:12466272, GO:0030331=PMID:12466272, GO:0005102=PMID:12466272, GO:0005730=PMID:12466272, GO:0005634=PMID:12466272, GO:0003676=GO_REF:0000002, GO:0016818=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0004004=PMID:12466272, GO:0030520=PMID:12466272} Q8TDD1 ATP-dependent RNA helicase DDX54 protein 20041203 {GO:0008026=IEA, GO:0006396=IDA, GO:0006355=IEA, GO:0016070=IDA, GO:0003723=IEA, GO:0003714=IDA, GO:0030331=IDA, GO:0005102=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0016818=IEA, GO:0005524=IEA, GO:0006351=IEA, GO:0004004=IDA, GO:0030520=TAS} RNA metabolic process, RNA processing, intracellular estrogen receptor signaling pathway, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus, nucleus ATP binding, ATP-dependent RNA helicase activity, ATP-dependent helicase activity, RNA binding, estrogen receptor binding, hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, nucleic acid binding, receptor binding, transcription corepressor activity Human DDX55 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q8NHQ9 ATP-dependent RNA helicase DDX55 protein 20130413 {GO:0008026=IEA, GO:0003723=IEA, GO:0003676=IEA, GO:0005524=IEA} ATP binding, ATP-dependent helicase activity, RNA binding, nucleic acid binding Human UniProtKB-KW:KW-0067 DDX56 LIFEdb UniProtKB {GO:0004004=PMID:10749921, GO:0008026=GO_REF:0000002, GO:0006364=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000054, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q9NY93 Probable ATP-dependent RNA helicase DDX56 protein 20100607 {GO:0004004=TAS, GO:0008026=IEA, GO:0006364=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0003676=IEA, GO:0005524=IEA} rRNA processing nucleolus ATP binding, ATP-dependent RNA helicase activity, ATP-dependent helicase activity, RNA binding, nucleic acid binding Human DDX58 BHF-UCL UniProtKB {GO:0005515=PMID:17079289, GO:0003725=PMID:17079289, GO:0003727=PMID:19211564, GO:0015629=PMID:19122199, GO:0042993=PMID:17079289, GO:0042802=PMID:21102435, GO:0005829=Reactome:REACT_25398, GO:0051091=PMID:17079289, GO:0005737=PMID:21102435, GO:0003690=GO_REF:0000019, GO:0045944=PMID:17079289, GO:0009597=PMID:17079289, GO:0032480=Reactome:REACT_25271, GO:0008026=GO_REF:0000002, GO:0030334=PMID:19122199, GO:0032728=PMID:17079289, GO:0034344=PMID:21616437, GO:0032727=PMID:19576794, GO:0032587=PMID:19122199, GO:0003676=GO_REF:0000002, GO:0009615=PMID:21616437, GO:0005524=GO_REF:0000037, GO:0039529=PMID:19211564, GO:0039528=PMID:21616437, GO:0045087=Reactome:REACT_6802, GO:0019048=GO_REF:0000037, GO:0002230=PMID:19609254, GO:0008270=PMID:18243112, GO:0005923=PMID:19122199, GO:0043330=GO_REF:0000019} O95786 Probable ATP-dependent RNA helicase DDX58 protein 20110418 {GO:0005515=IPI, GO:0003725=TAS, GO:0003727=IMP, GO:0015629=IDA, GO:0042993=IDA, GO:0042802=IPI, GO:0005829=TAS, GO:0051091=IC, GO:0005737=IDA, GO:0003690=IEA, GO:0045944=IDA, GO:0009597=IDA, GO:0032480=TAS, GO:0008026=IEA, GO:0030334=IDA, GO:0032728=IDA, GO:0034344=TAS, GO:0032727=IDA, GO:0032587=IDA, GO:0003676=IEA, GO:0009615=TAS, GO:0005524=IEA, GO:0039529=IMP, GO:0039528=TAS, GO:0045087=TAS, GO:0019048=IEA, GO:0002230=IMP, GO:0008270=IDA, GO:0005923=IDA, GO:0043330=IEA} RIG-I signaling pathway, cytoplasmic pattern recognition receptor signaling pathway in response to virus, detection of virus, innate immune response, negative regulation of type I interferon production, positive regulation of defense response to virus by host, positive regulation of interferon-alpha production, positive regulation of interferon-beta production, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription factor import into nucleus, positive regulation of transcription from RNA polymerase II promoter, regulation of cell migration, regulation of type III interferon production, response to exogenous dsRNA, response to virus, virus-host interaction actin cytoskeleton, cytoplasm, cytosol, ruffle membrane, tight junction ATP binding, ATP-dependent helicase activity, double-stranded DNA binding, double-stranded RNA binding, identical protein binding, nucleic acid binding, protein binding, single-stranded RNA binding, zinc ion binding Human DDX6 IntAct UniProtKB {GO:0008026=GO_REF:0000002, GO:0005515=PMID:16364915, GO:0003724=PMID:1579499, GO:0010467=Reactome:REACT_71, GO:0033962=PMID:20826699, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0010494=PMID:17392519, GO:0003723=GO_REF:0000037, GO:0004386=PMID:1579499, GO:0043928=Reactome:REACT_20518, GO:0005524=GO_REF:0000037, GO:0016442=PMID:20616046, GO:0005829=Reactome:REACT_20560, GO:0000932=PMID:20826699, GO:0000288=Reactome:REACT_20639} P26196 Probable ATP-dependent RNA helicase DDX6 protein 20130415 {GO:0008026=IEA, GO:0005515=IPI, GO:0003724=TAS, GO:0010467=TAS, GO:0033962=IDA, GO:0016070=TAS, GO:0016071=TAS, GO:0010494=IDA, GO:0003723=IEA, GO:0004386=TAS, GO:0043928=TAS, GO:0005524=IEA, GO:0016442=IDA, GO:0005829=TAS, GO:0000932=IDA, GO:0000288=TAS} RNA metabolic process, cytoplasmic mRNA processing body assembly, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay RNA-induced silencing complex, cytoplasmic mRNA processing body, cytoplasmic stress granule, cytosol ATP binding, ATP-dependent helicase activity, RNA binding, RNA helicase activity, helicase activity, protein binding Human UniProtKB:Q9NPI6 DDX60 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0003725=PMID:21791617, GO:0005515=PMID:21791617, GO:0003727=PMID:21791617, GO:0003723=GO_REF:0000019, GO:1900246=PMID:21791617, GO:1900245=PMID:21791617, GO:0009615=PMID:21791617, GO:0005524=GO_REF:0000037, GO:0005737=PMID:21791617, GO:0051607=GO_REF:0000019, GO:0003690=PMID:21791617, GO:0045087=GO_REF:0000037} Q8IY21 Probable ATP-dependent RNA helicase DDX60 protein 20120402 {GO:0008026=IEA, GO:0003725=IDA, GO:0005515=IPI, GO:0003727=IDA, GO:0003723=IEA, GO:1900246=IMP, GO:1900245=IMP, GO:0009615=IDA, GO:0005524=IEA, GO:0005737=IDA, GO:0051607=IEA, GO:0003690=IDA, GO:0045087=IEA} defense response to virus, innate immune response, positive regulation of MDA-5 signaling pathway, positive regulation of RIG-I signaling pathway, response to virus cytoplasm ATP binding, ATP-dependent helicase activity, RNA binding, double-stranded DNA binding, double-stranded RNA binding, protein binding, single-stranded RNA binding Human UniProtKB:Q9Y3B2 DDX60L UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q5H9U9 Probable ATP-dependent RNA helicase DDX60-like protein 20130413 {GO:0008026=IEA, GO:0003723=IEA, GO:0003676=IEA, GO:0005524=IEA} ATP binding, ATP-dependent helicase activity, RNA binding, nucleic acid binding Human UniProtKB-KW:KW-0067 DEAF1 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0005667=GO_REF:0000019, GO:0006357=GO_REF:0000019, GO:0006366=GO_REF:0000019, GO:0048706=GO_REF:0000024, GO:0001843=GO_REF:0000024, GO:0005576=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0007281=PMID:9773984, GO:0009653=PMID:9773984, GO:0033599=PMID:18826651, GO:0005737=GO_REF:0000039, GO:0008270=GO_REF:0000002} O75398 Deformed epidermal autoregulatory factor 1 homolog protein 20130415 {GO:0005515=IPI, GO:0005667=IEA, GO:0006357=IEA, GO:0006366=IEA, GO:0048706=ISS, GO:0001843=ISS, GO:0005576=IEA, GO:0003677=IEA, GO:0007281=TAS, GO:0009653=TAS, GO:0033599=IDA, GO:0005737=IEA, GO:0008270=IEA} anatomical structure morphogenesis, embryonic skeletal system development, germ cell development, neural tube closure, regulation of mammary gland epithelial cell proliferation, regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter cytoplasm, extracellular region, transcription factor complex DNA binding, protein binding, zinc ion binding Human UniProtKB:P42771 DEC1 PINC UniProtKB {GO:0008285=PMID:10612805} Q9P2X7 Deleted in esophageal cancer 1 protein 20030904 {GO:0008285=TAS} negative regulation of cell proliferation Human DECR1 HPA UniProtKB {GO:0008670=PMID:15531764, GO:0006635=Reactome:REACT_1473, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0070402=PMID:15531764, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0051289=PMID:15531764, GO:0005759=Reactome:REACT_164, GO:0016651=Reactome:REACT_164, GO:0016491=GO_REF:0000002, GO:0044255=Reactome:REACT_22279} Q16698 2,4-dienoyl-CoA reductase, mitochondrial protein 20110516 {GO:0008670=IDA, GO:0006635=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0070402=IDA, GO:0005739=IDA, GO:0005737=IDA, GO:0051289=IDA, GO:0005759=TAS, GO:0016651=TAS, GO:0016491=IEA, GO:0044255=TAS} cellular lipid metabolic process, fatty acid beta-oxidation, protein homotetramerization, small molecule metabolic process cytoplasm, mitochondrial matrix, mitochondrion, nucleolus, nucleus 2,4-dienoyl-CoA reductase (NADPH) activity, NADPH binding, oxidoreductase activity, oxidoreductase activity, acting on NAD(P)H Human DECR2 UniProtKB UniProtKB {GO:0008670=PMID:11514237, GO:0006636=PMID:11514237, GO:0019166=PMID:10811639, GO:0005102=PMID:20178365, GO:0016491=GO_REF:0000002, GO:0005778=GO_REF:0000019} Q9NUI1 Peroxisomal 2,4-dienoyl-CoA reductase protein 20120427 {GO:0008670=IDA, GO:0006636=IDA, GO:0019166=IDA, GO:0005102=IPI, GO:0016491=IEA, GO:0005778=IEA} unsaturated fatty acid biosynthetic process peroxisomal membrane 2,4-dienoyl-CoA reductase (NADPH) activity, oxidoreductase activity, receptor binding, trans-2-enoyl-CoA reductase (NADPH) activity Human UniProtKB:P50542 DEDD IntAct UniProtKB {GO:0008625=PMID:9774341, GO:0005515=PMID:20195357, GO:0046697=GO_REF:0000019, GO:0005737=GO_REF:0000024, GO:0042177=GO_REF:0000019, GO:0005730=GO_REF:0000024, GO:0042981=GO_REF:0000002, GO:0006917=GO_REF:0000024, GO:0007283=GO_REF:0000019, GO:0045892=GO_REF:0000024, GO:0003677=GO_REF:0000024, GO:0006351=GO_REF:0000037} O75618 Death effector domain-containing protein protein 20130415 {GO:0008625=TAS, GO:0005515=IPI, GO:0046697=IEA, GO:0005737=ISS, GO:0042177=IEA, GO:0005730=ISS, GO:0042981=IEA, GO:0006917=ISS, GO:0007283=IEA, GO:0045892=ISS, GO:0003677=ISS, GO:0006351=IEA} decidualization, extrinsic apoptotic signaling pathway via death domain receptors, induction of apoptosis, negative regulation of protein catabolic process, negative regulation of transcription, DNA-dependent, regulation of apoptotic process, spermatogenesis, transcription, DNA-dependent cytoplasm, nucleolus DNA binding, protein binding Human UniProtKB:Q06481 DEDD2 HPA UniProtKB {GO:0008625=PMID:11741985, GO:0005515=PMID:11741985, GO:0006396=PMID:11741985, GO:0016075=PMID:11741985, GO:0019725=PMID:11741985, GO:2001238=PMID:11741985, GO:0030262=PMID:11741985, GO:0005730=GO_REF:0000052, GO:0030159=PMID:11741985, GO:0005634=GO_REF:0000052, GO:0042981=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0035556=PMID:11741985, GO:0045892=PMID:11741985} Q8WXF8 DNA-binding death effector domain-containing protein 2 protein 20111111 {GO:0008625=IMP, GO:0005515=IPI, GO:0006396=NAS, GO:0016075=NAS, GO:0019725=NAS, GO:2001238=IMP, GO:0030262=IDA, GO:0005730=IDA, GO:0030159=NAS, GO:0005634=IDA, GO:0042981=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0035556=NAS, GO:0045892=NAS} RNA processing, apoptotic nuclear changes, cellular homeostasis, extrinsic apoptotic signaling pathway via death domain receptors, intracellular signal transduction, negative regulation of transcription, DNA-dependent, positive regulation of extrinsic apoptotic signaling pathway, rRNA catabolic process, regulation of apoptotic process, transcription, DNA-dependent nucleolus, nucleus DNA binding, protein binding, receptor signaling complex scaffold activity NOT Human DEF6 HPA UniProtKB {GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9H4E7 Differentially expressed in FDCP 6 homolog protein 20110516 {GO:0005737=IEA, GO:0005543=IEA, GO:0005886=IEA, GO:0005730=IDA, GO:0005634=IDA} cytoplasm, nucleolus, nucleus, plasma membrane phospholipid binding NOT Human DEF8 InterPro UniProtKB {GO:0035556=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q6ZN54 Differentially expressed in FDCP 8 homolog protein 20130413 {GO:0035556=IEA, GO:0008270=IEA} intracellular signal transduction zinc ion binding Human InterPro:IPR002219 DEFA1 Reactome UniProtKB {GO:0006955=PMID:10914484, GO:0051607=GO_REF:0000037, GO:0006935=PMID:10914484, GO:0005796=Reactome:REACT_115691, GO:0045087=Reactome:REACT_6802, GO:0050832=GO_REF:0000037, GO:0031640=GO_REF:0000037, GO:0005576=Reactome:REACT_116084, GO:0035578=Reactome:REACT_115688, GO:0005615=GO_REF:0000002, GO:0042742=GO_REF:0000037} P59665 Neutrophil defensin 1 protein 20110729 {GO:0006955=TAS, GO:0051607=IEA, GO:0006935=TAS, GO:0005796=TAS, GO:0045087=TAS, GO:0050832=IEA, GO:0031640=IEA, GO:0005576=TAS, GO:0035578=TAS, GO:0005615=IEA, GO:0042742=IEA} chemotaxis, defense response to bacterium, defense response to fungus, defense response to virus, immune response, innate immune response, killing of cells of other organism Golgi lumen, azurophil granule lumen, extracellular region, extracellular space Human DEFA3 Reactome UniProtKB {GO:0051607=GO_REF:0000037, GO:0005796=Reactome:REACT_115691, GO:0045087=Reactome:REACT_6802, GO:0050832=GO_REF:0000037, GO:0031640=GO_REF:0000037, GO:0005576=Reactome:REACT_116084, GO:0035578=Reactome:REACT_115688, GO:0005615=GO_REF:0000002, GO:0042742=GO_REF:0000037} P59666 Neutrophil defensin 3 protein 20110729 {GO:0051607=IEA, GO:0005796=TAS, GO:0045087=TAS, GO:0050832=IEA, GO:0031640=IEA, GO:0005576=TAS, GO:0035578=TAS, GO:0005615=IEA, GO:0042742=IEA} defense response to bacterium, defense response to fungus, defense response to virus, innate immune response, killing of cells of other organism Golgi lumen, azurophil granule lumen, extracellular region, extracellular space Human DEFA4 Reactome UniProtKB {GO:0005796=Reactome:REACT_115619, GO:0045087=Reactome:REACT_6802, GO:0050832=GO_REF:0000037, GO:0031640=GO_REF:0000037, GO:0005576=Reactome:REACT_115822, GO:0005615=GO_REF:0000002, GO:0042742=GO_REF:0000037} P12838 Neutrophil defensin 4 protein 20110727 {GO:0005796=TAS, GO:0045087=TAS, GO:0050832=IEA, GO:0031640=IEA, GO:0005576=TAS, GO:0005615=IEA, GO:0042742=IEA} defense response to bacterium, defense response to fungus, innate immune response, killing of cells of other organism Golgi lumen, extracellular region, extracellular space Human DEFA5 Reactome UniProtKB {GO:0030133=GO_REF:0000039, GO:0005796=Reactome:REACT_115904, GO:0045087=Reactome:REACT_6802, GO:0050832=GO_REF:0000037, GO:0031640=GO_REF:0000037, GO:0005576=Reactome:REACT_116162, GO:0005615=GO_REF:0000002, GO:0034774=Reactome:REACT_115910, GO:0042742=GO_REF:0000037} Q01523 Defensin-5 protein 20110729 {GO:0030133=IEA, GO:0005796=TAS, GO:0045087=TAS, GO:0050832=IEA, GO:0031640=IEA, GO:0005576=TAS, GO:0005615=IEA, GO:0034774=TAS, GO:0042742=IEA} defense response to bacterium, defense response to fungus, innate immune response, killing of cells of other organism Golgi lumen, extracellular region, extracellular space, secretory granule lumen, transport vesicle Human DEFA6 Reactome UniProtKB {GO:0005796=Reactome:REACT_115619, GO:0045087=Reactome:REACT_6802, GO:0050832=GO_REF:0000037, GO:0031640=GO_REF:0000037, GO:0005576=Reactome:REACT_115822, GO:0005615=GO_REF:0000002, GO:0042742=GO_REF:0000037} Q01524 Defensin-6 protein 20110729 {GO:0005796=TAS, GO:0045087=TAS, GO:0050832=IEA, GO:0031640=IEA, GO:0005576=TAS, GO:0005615=IEA, GO:0042742=IEA} defense response to bacterium, defense response to fungus, innate immune response, killing of cells of other organism Golgi lumen, extracellular region, extracellular space Human DEFB1 Reactome UniProtKB {GO:0009617=PMID:12054642, GO:0006955=PMID:10521347, GO:0002526=GO_REF:0000019, GO:0007186=PMID:10521347, GO:0006935=PMID:10521347, GO:0005796=Reactome:REACT_116066, GO:0045087=Reactome:REACT_6802, GO:0005576=Reactome:REACT_115591, GO:0033574=GO_REF:0000019, GO:0042742=GO_REF:0000037} P60022 Beta-defensin 1 protein 20130301 {GO:0009617=IDA, GO:0006955=TAS, GO:0002526=IEA, GO:0007186=TAS, GO:0006935=TAS, GO:0005796=TAS, GO:0045087=TAS, GO:0005576=TAS, GO:0033574=IEA, GO:0042742=IEA} G-protein coupled receptor signaling pathway, acute inflammatory response, chemotaxis, defense response to bacterium, immune response, innate immune response, response to bacterium, response to testosterone stimulus Golgi lumen, extracellular region Human DEFB103A Reactome UniProtKB {GO:0006965=PMID:11085990, GO:0005796=Reactome:REACT_116066, GO:0045087=Reactome:REACT_6802, GO:0005576=Reactome:REACT_116066, GO:0042742=GO_REF:0000037} P81534 Beta-defensin 103 protein 20110729 {GO:0006965=TAS, GO:0005796=TAS, GO:0045087=TAS, GO:0005576=TAS, GO:0042742=IEA} defense response to bacterium, innate immune response, positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria Golgi lumen, extracellular region Human DEFB103B null null {} null null null null {} null null null DEFB104A UniProtKB UniProtKB {GO:0005576=GO_REF:0000039, GO:0042742=GO_REF:0000037} Q8WTQ1 Beta-defensin 104 protein 20130413 {GO:0005576=IEA, GO:0042742=IEA} defense response to bacterium extracellular region Human UniProtKB-SubCell:SL-0243 DEFB127 UniProtKB UniProtKB {GO:0045087=PMID:10588992, GO:0005576=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0042742=PMID:10588992} Q9H1M4 Beta-defensin 127 protein 20040129 {GO:0045087=TAS, GO:0005576=IEA, GO:0005575=ND, GO:0042742=TAS} defense response to bacterium, innate immune response cellular_component, extracellular region Human DEFB4A Reactome UniProtKB {GO:0006955=PMID:10521347, GO:0007186=PMID:10521347, GO:0006935=PMID:10521347, GO:0005796=Reactome:REACT_116066, GO:0045087=Reactome:REACT_6802, GO:0005576=Reactome:REACT_115754, GO:0042742=GO_REF:0000037} O15263 Beta-defensin 4A protein 20130301 {GO:0006955=TAS, GO:0007186=TAS, GO:0006935=TAS, GO:0005796=TAS, GO:0045087=TAS, GO:0005576=TAS, GO:0042742=IEA} G-protein coupled receptor signaling pathway, chemotaxis, defense response to bacterium, immune response, innate immune response Golgi lumen, extracellular region Human DEGS1 Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0006636=PMID:9188692, GO:0005783=PMID:9188692, GO:0030148=Reactome:REACT_115810, GO:0009055=PMID:9188692, GO:0044281=Reactome:REACT_111217, GO:0005739=GO_REF:0000039, GO:0016020=PMID:9188692, GO:0005887=PMID:9188692, GO:0005789=Reactome:REACT_19261, GO:0006633=GO_REF:0000002, GO:0016021=GO_REF:0000002, GO:0016705=GO_REF:0000002} O15121 Sphingolipid delta(4)-desaturase DES1 protein 20130301 {GO:0006665=TAS, GO:0006636=TAS, GO:0005783=TAS, GO:0030148=TAS, GO:0009055=TAS, GO:0044281=TAS, GO:0005739=IEA, GO:0016020=TAS, GO:0005887=TAS, GO:0005789=TAS, GO:0006633=IEA, GO:0016021=IEA, GO:0016705=IEA} fatty acid biosynthetic process, small molecule metabolic process, sphingolipid biosynthetic process, sphingolipid metabolic process, unsaturated fatty acid biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, integral to plasma membrane, membrane, mitochondrion electron carrier activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Human DEK PINC UniProtKB {GO:2001032=GO_REF:0000019, GO:0007165=PMID:9050861, GO:0042393=PMID:12140263, GO:0006357=PMID:9050861, GO:0006366=PMID:9050861, GO:2000779=PMID:21653549, GO:0005634=PMID:21653549, GO:0003676=GO_REF:0000002, GO:0019079=PMID:9050861, GO:0003677=GO_REF:0000037, GO:0016568=GO_REF:0000037} P35659 Protein DEK protein 20031119 {GO:2001032=IEA, GO:0007165=TAS, GO:0042393=IDA, GO:0006357=TAS, GO:0006366=TAS, GO:2000779=IMP, GO:0005634=IDA, GO:0003676=IEA, GO:0019079=TAS, GO:0003677=IEA, GO:0016568=IEA} chromatin modification, regulation of double-strand break repair, regulation of double-strand break repair via nonhomologous end joining, regulation of transcription from RNA polymerase II promoter, signal transduction, transcription from RNA polymerase II promoter, viral genome replication nucleus DNA binding, histone binding, nucleic acid binding Human DENND1A UniProtKB UniProtKB {GO:0017112=PMID:20937701, GO:0042734=GO_REF:0000039, GO:0030665=GO_REF:0000039, GO:0017124=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000037, GO:0030136=PMID:20937701, GO:0043025=GO_REF:0000019, GO:0048488=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0030425=GO_REF:0000019, GO:0006897=PMID:20937701} Q8TEH3 DENN domain-containing protein 1A protein 20121004 {GO:0017112=IDA, GO:0042734=IEA, GO:0030665=IEA, GO:0017124=IEA, GO:0030054=IEA, GO:0005886=IEA, GO:0030136=IDA, GO:0043025=IEA, GO:0048488=IEA, GO:0015031=IEA, GO:0030425=IEA, GO:0006897=IMP} endocytosis, protein transport, synaptic vesicle endocytosis cell junction, clathrin-coated vesicle, clathrin-coated vesicle membrane, dendrite, neuronal cell body, plasma membrane, presynaptic membrane Rab guanyl-nucleotide exchange factor activity, SH3 domain binding Human DENND1C UniProtKB UniProtKB {GO:0017112=PMID:20937701, GO:0030136=GO_REF:0000039, GO:0005829=GO_REF:0000039} Q8IV53 DENN domain-containing protein 1C protein 20121004 {GO:0017112=IDA, GO:0030136=IEA, GO:0005829=IEA} clathrin-coated vesicle, cytosol Rab guanyl-nucleotide exchange factor activity Human DENND2A UniProtKB UniProtKB {GO:0017112=PMID:20937701, GO:0005737=GO_REF:0000037, GO:0042147=PMID:20937701, GO:0015629=PMID:20937701, GO:0015031=GO_REF:0000037} Q9ULE3 DENN domain-containing protein 2A protein 20121004 {GO:0017112=IDA, GO:0005737=IEA, GO:0042147=IMP, GO:0015629=IDA, GO:0015031=IEA} protein transport, retrograde transport, endosome to Golgi actin cytoskeleton, cytoplasm Rab guanyl-nucleotide exchange factor activity Human DENND2D UniProtKB UniProtKB {GO:0017112=PMID:20937701, GO:0005737=GO_REF:0000039} Q9H6A0 DENN domain-containing protein 2D protein 20121004 {GO:0017112=IDA, GO:0005737=IEA} cytoplasm Rab guanyl-nucleotide exchange factor activity Human DENND3 ENSEMBL UniProtKB {GO:0017112=GO_REF:0000019, GO:0008333=GO_REF:0000024, GO:0044257=GO_REF:0000019} B3KRG7 cDNA FLJ34237 fis, clone FCBBF3027328 protein 20130413 {GO:0017112=IEA, GO:0008333=ISS, GO:0044257=IEA} cellular protein catabolic process, endosome to lysosome transport Rab guanyl-nucleotide exchange factor activity Human Ensembl:ENSMUSP00000046774 DENND4A UniProtKB UniProtKB {GO:0017112=PMID:20937701, GO:0006355=PMID:8056341, GO:0005634=GO_REF:0000029, GO:0003677=PMID:8056341, GO:0006351=GO_REF:0000037} Q7Z401 C-myc promoter-binding protein protein 20121004 {GO:0017112=IDA, GO:0006355=NAS, GO:0005634=NAS, GO:0003677=NAS, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, Rab guanyl-nucleotide exchange factor activity Human DENND4C UniProtKB UniProtKB {GO:0017112=PMID:20937701, GO:0032869=GO_REF:0000024, GO:0005886=GO_REF:0000024, GO:0032593=GO_REF:0000024, GO:0015031=GO_REF:0000037, GO:0072659=GO_REF:0000024, GO:0030659=GO_REF:0000039, GO:0005829=GO_REF:0000024, GO:0030904=GO_REF:0000019} Q5VZ89 DENN domain-containing protein 4C protein 20121005 {GO:0017112=IDA, GO:0032869=ISS, GO:0005886=ISS, GO:0032593=ISS, GO:0015031=IEA, GO:0072659=ISS, GO:0030659=IEA, GO:0005829=ISS, GO:0030904=IEA} cellular response to insulin stimulus, protein localization to plasma membrane, protein transport cytoplasmic vesicle membrane, cytosol, insulin-responsive compartment, plasma membrane, retromer complex Rab guanyl-nucleotide exchange factor activity Human UniProtKB:A6H8H2 DENND5A UniProtKB UniProtKB {GO:0017112=PMID:20937701, GO:0005262=GO_REF:0000033, GO:0017137=GO_REF:0000019, GO:0005794=GO_REF:0000019, GO:0050982=GO_REF:0000033, GO:0016020=GO_REF:0000033} Q6IQ26 DENN domain-containing protein 5A protein 20121004 {GO:0017112=IDA, GO:0005262=IBA, GO:0017137=IEA, GO:0005794=IEA, GO:0050982=IBA, GO:0016020=IBA} detection of mechanical stimulus Golgi apparatus, membrane Rab GTPase binding, Rab guanyl-nucleotide exchange factor activity, calcium channel activity Human DENND5B UniProtKB UniProtKB {GO:0017112=PMID:20937701, GO:0005262=GO_REF:0000033, GO:0050982=GO_REF:0000033, GO:0016020=GO_REF:0000033, GO:0016021=GO_REF:0000037} Q6ZUT9 DENN domain-containing protein 5B protein 20121004 {GO:0017112=IDA, GO:0005262=IBA, GO:0050982=IBA, GO:0016020=IBA, GO:0016021=IEA} detection of mechanical stimulus integral to membrane, membrane Rab guanyl-nucleotide exchange factor activity, calcium channel activity Human DENR IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0003743=GO_REF:0000002, GO:0005575=GO_REF:0000015} O43583 Density-regulated protein protein 20130415 {GO:0005515=IPI, GO:0003674=ND, GO:0008150=ND, GO:0003743=IEA, GO:0005575=ND} biological_process cellular_component molecular_function, protein binding, translation initiation factor activity Human UniProtKB:Q8WX92 DEPDC1 UniProtKB UniProtKB {GO:0005515=PMID:20587513, GO:0035556=GO_REF:0000002, GO:0017053=PMID:20587513, GO:0005634=PMID:20587513, GO:0045892=PMID:20587513, GO:0006351=GO_REF:0000037, GO:0005096=GO_REF:0000037} Q5TB30 DEP domain-containing protein 1A protein 20101214 {GO:0005515=IPI, GO:0035556=IEA, GO:0017053=IDA, GO:0005634=IDA, GO:0045892=IDA, GO:0006351=IEA, GO:0005096=IEA} intracellular signal transduction, negative regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus, transcriptional repressor complex GTPase activator activity, protein binding Human DEPDC1B Reactome UniProtKB {GO:0035556=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007264=Reactome:REACT_11044, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} Q8WUY9 DEP domain-containing protein 1B protein 20130301 {GO:0035556=IEA, GO:0005622=IEA, GO:0051056=TAS, GO:0007264=TAS, GO:0005829=TAS, GO:0005096=IEA} intracellular signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol, intracellular GTPase activator activity Human DEPDC5 InterPro UniProtKB {GO:0035556=GO_REF:0000002} O75140 DEP domain-containing protein 5 protein 20130413 {GO:0035556=IEA} intracellular signal transduction Human InterPro:IPR000591 DEPDC7 Reactome UniProtKB {GO:0035556=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0007264=Reactome:REACT_11044, GO:0005575=GO_REF:0000015, GO:0005829=Reactome:REACT_9982} Q96QD5 DEP domain-containing protein 7 protein 20130301 {GO:0035556=IEA, GO:0051056=TAS, GO:0008150=ND, GO:0003674=ND, GO:0007264=TAS, GO:0005575=ND, GO:0005829=TAS} biological_process, intracellular signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cellular_component, cytosol molecular_function Human DEPTOR IntAct UniProtKB {GO:0005622=GO_REF:0000054, GO:0005515=PMID:19446321, GO:0035556=GO_REF:0000002, GO:0045792=PMID:19446321, GO:0032007=PMID:19446321, GO:0042981=PMID:19446321, GO:0006469=PMID:19446321} Q8TB45 DEP domain-containing mTOR-interacting protein protein 20130415 {GO:0005622=IDA, GO:0005515=IPI, GO:0035556=IEA, GO:0045792=IMP, GO:0032007=IMP, GO:0042981=IMP, GO:0006469=IMP} intracellular signal transduction, negative regulation of TOR signaling cascade, negative regulation of cell size, negative regulation of protein kinase activity, regulation of apoptotic process intracellular protein binding Human UniProtKB:P42346 DERA UniProtKB UniProtKB {GO:0009264=GO_REF:0000002, GO:0005737=GO_REF:0000002, GO:0004139=PMID:9226884, GO:0046121=PMID:9226884, GO:0046386=GO_REF:0000041, GO:0005575=GO_REF:0000015} Q9Y315 Putative deoxyribose-phosphate aldolase protein 20081106 {GO:0009264=IEA, GO:0005737=IEA, GO:0004139=IDA, GO:0046121=IDA, GO:0046386=IEA, GO:0005575=ND} deoxyribonucleoside catabolic process, deoxyribonucleotide catabolic process, deoxyribose phosphate catabolic process cellular_component, cytoplasm deoxyribose-phosphate aldolase activity Human DERL1 HPA UniProtKB {GO:0006986=PMID:15215855, GO:0005515=PMID:18555783, GO:0042288=PMID:15215855, GO:0019060=PMID:15215856, GO:0005783=GO_REF:0000052, GO:0005770=GO_REF:0000019, GO:0030970=PMID:15215855, GO:0030176=PMID:15215856, GO:0030433=PMID:15215856, GO:0045184=PMID:15215856, GO:0030968=PMID:15215856, GO:0004872=PMID:15215856, GO:0016021=PMID:15215855, GO:0034620=GO_REF:0000019, GO:0005769=GO_REF:0000019} Q9BUN8 Derlin-1 protein 20090616 {GO:0006986=IMP, GO:0005515=IPI, GO:0042288=IDA, GO:0019060=TAS, GO:0005783=IDA, GO:0005770=IEA, GO:0030970=IMP, GO:0030176=IDA, GO:0030433=IDA, GO:0045184=TAS, GO:0030968=IDA, GO:0004872=NAS, GO:0016021=IDA, GO:0034620=IEA, GO:0005769=IEA} ER-associated protein catabolic process, cellular response to unfolded protein, endoplasmic reticulum unfolded protein response, establishment of protein localization, intracellular transport of viral proteins in host cell, response to unfolded protein, retrograde protein transport, ER to cytosol early endosome, endoplasmic reticulum, integral to endoplasmic reticulum membrane, integral to membrane, late endosome MHC class I protein binding, protein binding, receptor activity Human DERL2 UniProtKB UniProtKB {GO:0005515=PMID:16449189, GO:0008284=PMID:11500051, GO:0005783=PMID:15215855, GO:0030307=PMID:11500051, GO:0005770=GO_REF:0000019, GO:0030970=PMID:16449189, GO:0030176=PMID:16449189, GO:0030433=PMID:16449189, GO:0005769=GO_REF:0000019, GO:0030968=PMID:16449189} Q9GZP9 Derlin-2 protein 20120708 {GO:0005515=IPI, GO:0008284=IDA, GO:0005783=IDA, GO:0030307=IDA, GO:0005770=IEA, GO:0030970=IMP, GO:0030176=IDA, GO:0030433=IMP, GO:0005769=IEA, GO:0030968=IDA} ER-associated protein catabolic process, endoplasmic reticulum unfolded protein response, positive regulation of cell growth, positive regulation of cell proliferation, retrograde protein transport, ER to cytosol early endosome, endoplasmic reticulum, integral to endoplasmic reticulum membrane, late endosome protein binding Human UniProtKB:Q92611 DERL3 UniProtKB UniProtKB {GO:0005515=PMID:16449189, GO:0030176=PMID:16449189, GO:0030433=PMID:22607976, GO:0018279=PMID:22607976, GO:0030968=PMID:16449189} Q96Q80 Derlin-3 protein 20120708 {GO:0005515=IPI, GO:0030176=IDA, GO:0030433=IMP, GO:0018279=IMP, GO:0030968=IDA} ER-associated protein catabolic process, endoplasmic reticulum unfolded protein response, protein N-linked glycosylation via asparagine integral to endoplasmic reticulum membrane protein binding Human UniProtKB:Q92611 DES BHF-UCL UniProtKB {GO:0005882=GO_REF:0000019, GO:0005515=PMID:11353857, GO:0008092=PMID:11309420, GO:0030018=PMID:9415431, GO:0031594=GO_REF:0000019, GO:0030049=Reactome:REACT_16969, GO:0008016=PMID:9697706, GO:0005829=Reactome:REACT_17057, GO:0005916=GO_REF:0000019, GO:0042383=GO_REF:0000019, GO:0006936=PMID:9697706, GO:0007010=PMID:9736733, GO:0005200=PMID:9736733} P17661 Desmin protein 20120508 {GO:0005882=IEA, GO:0005515=IPI, GO:0008092=IPI, GO:0030018=IDA, GO:0031594=IEA, GO:0030049=TAS, GO:0008016=TAS, GO:0005829=TAS, GO:0005916=IEA, GO:0042383=IEA, GO:0006936=TAS, GO:0007010=TAS, GO:0005200=TAS} cytoskeleton organization, muscle contraction, muscle filament sliding, regulation of heart contraction Z disc, cytosol, fascia adherens, intermediate filament, neuromuscular junction, sarcolemma cytoskeletal protein binding, protein binding, structural constituent of cytoskeleton Human UniProtKB:Q04020 DET1 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039} Q7L5Y6 DET1 homolog protein 20130413 {GO:0005634=IEA} nucleus Human UniProtKB-SubCell:SL-0191 DEXI null null {} null null null null {} null null null DFFA HPA UniProtKB {GO:0000790=PMID:19882353, GO:0043066=PMID:9564035, GO:0006915=Reactome:REACT_578, GO:0005634=GO_REF:0000052, GO:0006917=GO_REF:0000019, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_13756, GO:0005622=GO_REF:0000002, GO:0035556=PMID:9108473, GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0004536=PMID:9108473, GO:0006309=Reactome:REACT_1213, GO:0005654=Reactome:REACT_13689} O00273 DNA fragmentation factor subunit alpha protein 20111111 {GO:0000790=IDA, GO:0043066=IDA, GO:0006915=TAS, GO:0005634=IDA, GO:0006917=IEA, GO:0006921=TAS, GO:0005829=TAS, GO:0005622=IEA, GO:0035556=TAS, GO:0007165=IEA, GO:0005737=IDA, GO:0004536=TAS, GO:0006309=TAS, GO:0005654=TAS} apoptotic DNA fragmentation, apoptotic process, cellular component disassembly involved in execution phase of apoptosis, induction of apoptosis, intracellular signal transduction, negative regulation of apoptotic process, signal transduction cytoplasm, cytosol, intracellular, nuclear chromatin, nucleoplasm, nucleus deoxyribonuclease activity Human DFFB InterPro UniProtKB {GO:0000790=PMID:19882353, GO:0006915=GO_REF:0000002, GO:0005634=GO_REF:0000019, GO:0006917=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_13756, GO:0035556=PMID:9108473, GO:0005622=GO_REF:0000002, GO:0004516=GO_REF:0000019, GO:0005737=GO_REF:0000002, GO:0004536=GO_REF:0000019, GO:0016787=GO_REF:0000002, GO:0006309=GO_REF:0000019, GO:0030263=PMID:10959840, GO:0005654=Reactome:REACT_13708, GO:0019899=PMID:10959840} Q96P73 DNAation factor, 40kDa, beta polypeptide (Caspase-activated DNase), isoform CRA_d protein 20130413 {GO:0000790=IDA, GO:0006915=IEA, GO:0005634=IEA, GO:0006917=IEA, GO:0003677=IEA, GO:0006921=TAS, GO:0005829=TAS, GO:0035556=TAS, GO:0005622=IEA, GO:0004516=IEA, GO:0005737=IEA, GO:0004536=IEA, GO:0016787=IEA, GO:0006309=IEA, GO:0030263=IDA, GO:0005654=TAS, GO:0019899=IPI} apoptotic DNA fragmentation, apoptotic chromosome condensation, apoptotic process, cellular component disassembly involved in execution phase of apoptosis, induction of apoptosis, intracellular signal transduction cytoplasm, cytosol, intracellular, nuclear chromatin, nucleoplasm, nucleus DNA binding, deoxyribonuclease activity, enzyme binding, hydrolase activity, nicotinate phosphoribosyltransferase activity Human InterPro:IPR003508 DFNA5 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0008285=PMID:18223688, GO:0060113=GO_REF:0000019, GO:0007605=PMID:9771715, GO:0006915=PMID:21522185, GO:0006917=PMID:21522185} O60443 Non-syndromic hearing impairment protein 5 protein 20081203 {GO:0005737=IDA, GO:0008285=IDA, GO:0060113=IEA, GO:0007605=TAS, GO:0006915=IDA, GO:0006917=IDA} apoptotic process, induction of apoptosis, inner ear receptor cell differentiation, negative regulation of cell proliferation, sensory perception of sound cytoplasm Human DFNB31 HGNC UniProtKB {GO:0005515=PMID:23023331, GO:0005929=GO_REF:0000019, GO:0005737=PMID:16434480, GO:0060122=GO_REF:0000024, GO:0001895=PMID:17171570, GO:0002142=GO_REF:0000019, GO:0007605=PMID:17171570, GO:0005884=GO_REF:0000019, GO:0032420=GO_REF:0000024, GO:0050953=PMID:17171570, GO:0030426=GO_REF:0000039} Q9P202 Whirlin protein 20070807 {GO:0005515=IPI, GO:0005929=IEA, GO:0005737=IDA, GO:0060122=ISS, GO:0001895=IMP, GO:0002142=IEA, GO:0007605=IMP, GO:0005884=IEA, GO:0032420=ISS, GO:0050953=IMP, GO:0030426=IEA} inner ear receptor stereocilium organization, retina homeostasis, sensory perception of light stimulus, sensory perception of sound actin filament, cilium, cytoplasm, growth cone, stereocilia ankle link complex, stereocilium protein binding Human DGAT1 BHF-UCL UniProtKB {GO:0008374=GO_REF:0000002, GO:0016746=PMID:9756920, GO:0019915=GO_REF:0000024, GO:0003846=GO_REF:0000019, GO:0055089=GO_REF:0000019, GO:0050252=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0034379=PMID:15308631, GO:0035336=GO_REF:0000024, GO:0019432=Reactome:REACT_1190, GO:0005789=Reactome:REACT_121007, GO:0006641=PMID:9756920, GO:0004144=Reactome:REACT_659, GO:0036155=Reactome:REACT_121122, GO:0016021=GO_REF:0000024, GO:0006644=Reactome:REACT_120870, GO:0044255=Reactome:REACT_22279, GO:0046339=GO_REF:0000024, GO:0046474=Reactome:REACT_121401} O75907 Diacylglycerol O-acyltransferase 1 protein 20111130 {GO:0008374=IEA, GO:0016746=TAS, GO:0019915=ISS, GO:0003846=IEA, GO:0055089=IEA, GO:0050252=IEA, GO:0044281=TAS, GO:0034379=IMP, GO:0035336=ISS, GO:0019432=TAS, GO:0005789=TAS, GO:0006641=TAS, GO:0004144=EXP, GO:0036155=TAS, GO:0016021=ISS, GO:0006644=TAS, GO:0044255=TAS, GO:0046339=ISS, GO:0046474=TAS} acylglycerol acyl-chain remodeling, cellular lipid metabolic process, diacylglycerol metabolic process, fatty acid homeostasis, glycerophospholipid biosynthetic process, lipid storage, long-chain fatty-acyl-CoA metabolic process, phospholipid metabolic process, small molecule metabolic process, triglyceride biosynthetic process, triglyceride metabolic process, very-low-density lipoprotein particle assembly endoplasmic reticulum membrane, integral to membrane 2-acylglycerol O-acyltransferase activity, O-acyltransferase activity, diacylglycerol O-acyltransferase activity, retinol O-fatty-acyltransferase activity, transferase activity, transferring acyl groups Human UniProtKB:Q9Z2A7 DGCR14 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0000398=PMID:11991638, GO:0005634=PMID:8703114, GO:0071013=PMID:11991638, GO:0007399=PMID:8703114} Q96DF8 Protein DGCR14 protein 20110302 {GO:0003674=ND, GO:0000398=IC, GO:0005634=ISS, GO:0071013=IDA, GO:0007399=ISS} mRNA splicing, via spliceosome, nervous system development catalytic step 2 spliceosome, nucleus molecular_function Human DGCR2 PINC UniProtKB {GO:0009887=PMID:7655455, GO:0030246=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037} P98153 Integral membrane protein DGCR2/IDD protein 20031120 {GO:0009887=TAS, GO:0030246=IEA, GO:0016021=IEA, GO:0007155=IEA} cell adhesion, organ morphogenesis integral to membrane carbohydrate binding Human DGCR6 PINC UniProtKB {GO:0003674=GO_REF:0000015, GO:0005578=PMID:8733130, GO:0009887=PMID:8733130, GO:0005634=GO_REF:0000039, GO:0007155=PMID:8733130} Q14129 Protein DGCR6 protein 20031120 {GO:0003674=ND, GO:0005578=TAS, GO:0009887=TAS, GO:0005634=IEA, GO:0007155=TAS} cell adhesion, organ morphogenesis nucleus, proteinaceous extracellular matrix molecular_function Human DGCR6L UniProtKB UniProtKB {GO:0005634=GO_REF:0000039} Q9BY27 Protein DGCR6L protein 20130413 {GO:0005634=IEA} nucleus Human UniProtKB-SubCell:SL-0191 DGCR8 HPA UniProtKB {GO:0005515=PMID:15574589, GO:0003725=PMID:17704815, GO:0010467=Reactome:REACT_71, GO:0005737=GO_REF:0000052, GO:0015630=GO_REF:0000052, GO:0031053=PMID:15574589, GO:0005730=GO_REF:0000052, GO:0005654=Reactome:REACT_12414, GO:0005634=GO_REF:0000052, GO:0046872=GO_REF:0000037} Q8WYQ5 Microprocessor complex subunit DGCR8 protein 20101115 {GO:0005515=IPI, GO:0003725=IDA, GO:0010467=TAS, GO:0005737=IDA, GO:0015630=IDA, GO:0031053=IDA, GO:0005730=IDA, GO:0005654=TAS, GO:0005634=IDA, GO:0046872=IEA} gene expression, primary miRNA processing cytoplasm, microtubule cytoskeleton, nucleolus, nucleoplasm, nucleus double-stranded RNA binding, metal ion binding, protein binding Human DGKA UniProtKB UniProtKB {GO:0035556=GO_REF:0000002, GO:0005543=GO_REF:0000019, GO:0005886=Reactome:REACT_19402, GO:0016301=GO_REF:0000038, GO:0007596=Reactome:REACT_604, GO:0005509=GO_REF:0000002, GO:0004143=GO_REF:0000003, GO:0030168=Reactome:REACT_798, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000038, GO:0007205=GO_REF:0000002, GO:0005829=GO_REF:0000019} Q3ZE25 Diacylglycerol kinase alpha protein 20130413 {GO:0035556=IEA, GO:0005543=IEA, GO:0005886=TAS, GO:0016301=IEA, GO:0007596=TAS, GO:0005509=IEA, GO:0004143=IEA, GO:0030168=TAS, GO:0005524=IEA, GO:0046872=IEA, GO:0007205=IEA, GO:0005829=IEA} blood coagulation, intracellular signal transduction, platelet activation, protein kinase C-activating G-protein coupled receptor signaling pathway cytosol, plasma membrane ATP binding, calcium ion binding, diacylglycerol kinase activity, kinase activity, metal ion binding, phospholipid binding Human UniProtKB-KW:KW-0418 DGKB Reactome UniProtKB {GO:0035556=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0005886=Reactome:REACT_19402, GO:0007596=Reactome:REACT_604, GO:0005509=GO_REF:0000002, GO:0004143=GO_REF:0000003, GO:0030168=Reactome:REACT_798, GO:0005524=GO_REF:0000037, GO:0007205=GO_REF:0000002} Q9Y6T7 Diacylglycerol kinase beta protein 20130301 {GO:0035556=IEA, GO:0005737=IEA, GO:0005886=TAS, GO:0007596=TAS, GO:0005509=IEA, GO:0004143=IEA, GO:0030168=TAS, GO:0005524=IEA, GO:0007205=IEA} blood coagulation, intracellular signal transduction, platelet activation, protein kinase C-activating G-protein coupled receptor signaling pathway cytoplasm, plasma membrane ATP binding, calcium ion binding, diacylglycerol kinase activity Human DGKD Reactome UniProtKB {GO:0010033=PMID:12200442, GO:0046982=PMID:12200442, GO:0005886=Reactome:REACT_19402, GO:0030168=Reactome:REACT_798, GO:0007275=PMID:12200442, GO:0015031=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0042803=PMID:12200442, GO:0046872=GO_REF:0000037, GO:0007205=PMID:12200442, GO:0006897=GO_REF:0000037, GO:0019992=PMID:12200442, GO:0035556=GO_REF:0000002, GO:0007165=PMID:8626538, GO:0005737=PMID:12200442, GO:0005543=GO_REF:0000002, GO:0007173=PMID:12200442, GO:0007596=Reactome:REACT_604, GO:0019932=PMID:12200442, GO:0004143=PMID:12200442, GO:0016049=PMID:12200442, GO:0051260=PMID:12200442, GO:0046339=PMID:12200442} Q16760 Diacylglycerol kinase delta protein 20130301 {GO:0010033=IDA, GO:0046982=IDA, GO:0005886=TAS, GO:0030168=TAS, GO:0007275=NAS, GO:0015031=IEA, GO:0005524=IEA, GO:0042803=IDA, GO:0046872=IEA, GO:0007205=NAS, GO:0006897=IEA, GO:0019992=NAS, GO:0035556=IEA, GO:0007165=TAS, GO:0005737=IDA, GO:0005543=IEA, GO:0007173=NAS, GO:0007596=TAS, GO:0019932=NAS, GO:0004143=IDA, GO:0016049=NAS, GO:0051260=IDA, GO:0046339=IC} blood coagulation, cell growth, diacylglycerol metabolic process, endocytosis, epidermal growth factor receptor signaling pathway, intracellular signal transduction, multicellular organismal development, platelet activation, protein homooligomerization, protein kinase C-activating G-protein coupled receptor signaling pathway, protein transport, response to organic substance, second-messenger-mediated signaling, signal transduction cytoplasm, plasma membrane ATP binding, diacylglycerol binding, diacylglycerol kinase activity, metal ion binding, phospholipid binding, protein heterodimerization activity, protein homodimerization activity Human DGKE UniProtKB UniProtKB {GO:0035556=GO_REF:0000002, GO:0005886=Reactome:REACT_19402, GO:0007596=Reactome:REACT_604, GO:0004143=GO_REF:0000003, GO:0030168=Reactome:REACT_798, GO:0008654=PMID:8626589, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000038, GO:0007205=GO_REF:0000002} Q8TBM4 Diacylglycerol kinase epsilon protein 20130413 {GO:0035556=IEA, GO:0005886=TAS, GO:0007596=TAS, GO:0004143=IEA, GO:0030168=TAS, GO:0008654=TAS, GO:0016021=IEA, GO:0005524=IEA, GO:0046872=IEA, GO:0007205=IEA} blood coagulation, intracellular signal transduction, phospholipid biosynthetic process, platelet activation, protein kinase C-activating G-protein coupled receptor signaling pathway integral to membrane, plasma membrane ATP binding, diacylglycerol kinase activity, metal ion binding Human UniProtKB-KW:KW-0479 DGKG HPA UniProtKB {GO:0035556=GO_REF:0000002, GO:0007165=PMID:8034597, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0007596=Reactome:REACT_604, GO:0048666=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0004143=GO_REF:0000003, GO:0030168=Reactome:REACT_798, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000038, GO:0007205=GO_REF:0000002} P49619 Diacylglycerol kinase gamma protein 20110516 {GO:0035556=IEA, GO:0007165=TAS, GO:0005737=IDA, GO:0005886=IDA, GO:0007596=TAS, GO:0048666=IEA, GO:0005509=IEA, GO:0004143=IEA, GO:0030168=TAS, GO:0005524=IEA, GO:0046872=IEA, GO:0007205=IEA} blood coagulation, intracellular signal transduction, neuron development, platelet activation, protein kinase C-activating G-protein coupled receptor signaling pathway, signal transduction cytoplasm, plasma membrane ATP binding, calcium ion binding, diacylglycerol kinase activity, metal ion binding Human DGKH HPA UniProtKB {GO:0031965=GO_REF:0000052, GO:0005886=Reactome:REACT_19402, GO:0030168=Reactome:REACT_798, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037, GO:0051259=PMID:12810723, GO:0007205=PMID:12810723, GO:0046872=GO_REF:0000037, GO:0035556=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0004143=PMID:12810723, GO:0005768=PMID:12810723} Q86XP1 Diacylglycerol kinase eta protein 20110516 {GO:0031965=IDA, GO:0005886=TAS, GO:0030168=TAS, GO:0005634=IDA, GO:0005524=IEA, GO:0051259=IMP, GO:0007205=IMP, GO:0046872=IEA, GO:0035556=IEA, GO:0005737=IDA, GO:0005543=IEA, GO:0007596=TAS, GO:0004143=IMP, GO:0005768=IDA} blood coagulation, intracellular signal transduction, platelet activation, protein kinase C-activating G-protein coupled receptor signaling pathway, protein oligomerization cytoplasm, endosome, nuclear membrane, nucleus, plasma membrane ATP binding, diacylglycerol kinase activity, metal ion binding, phospholipid binding Human DGKI IntAct UniProtKB {GO:0005515=PMID:17986458, GO:0048471=GO_REF:0000019, GO:0005886=Reactome:REACT_19402, GO:0030168=Reactome:REACT_798, GO:0046579=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0007205=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0035556=GO_REF:0000002, GO:0005737=PMID:9830018, GO:0007596=Reactome:REACT_604, GO:0004143=GO_REF:0000003, GO:0005095=GO_REF:0000019, GO:0017016=GO_REF:0000019, GO:0032317=GO_REF:0000019, GO:0032045=GO_REF:0000019} O75912 Diacylglycerol kinase iota protein 20130415 {GO:0005515=IPI, GO:0048471=IEA, GO:0005886=TAS, GO:0030168=TAS, GO:0046579=IEA, GO:0005634=IEA, GO:0005524=IEA, GO:0007205=IEA, GO:0046872=IEA, GO:0035556=IEA, GO:0005737=TAS, GO:0007596=TAS, GO:0004143=IEA, GO:0005095=IEA, GO:0017016=IEA, GO:0032317=IEA, GO:0032045=IEA} blood coagulation, intracellular signal transduction, platelet activation, positive regulation of Ras protein signal transduction, protein kinase C-activating G-protein coupled receptor signaling pathway, regulation of Rap GTPase activity cytoplasm, guanyl-nucleotide exchange factor complex, nucleus, perinuclear region of cytoplasm, plasma membrane ATP binding, GTPase inhibitor activity, Ras GTPase binding, diacylglycerol kinase activity, metal ion binding, protein binding Human UniProtKB:P40337-3 DGKQ Reactome UniProtKB {GO:0005515=PMID:10066731, GO:0005886=Reactome:REACT_19402, GO:0030168=Reactome:REACT_798, GO:0005634=PMID:17664281, GO:0005524=GO_REF:0000037, GO:0070528=PMID:15632189, GO:0046872=GO_REF:0000037, GO:0007205=GO_REF:0000002, GO:0005829=PMID:10066731, GO:0035556=GO_REF:0000002, GO:0005737=PMID:15632189, GO:0016607=PMID:12799190, GO:0007186=PMID:15632189, GO:0007596=Reactome:REACT_604, GO:0043274=PMID:12799190, GO:0070493=PMID:15632189, GO:0019933=PMID:17664281, GO:0004143=PMID:10066731, GO:0033198=PMID:15632189, GO:0033613=PMID:17664281, GO:0019900=PMID:15632189, GO:0005856=PMID:10066731} P52824 Diacylglycerol kinase theta protein 20130301 {GO:0005515=IPI, GO:0005886=TAS, GO:0030168=TAS, GO:0005634=IDA, GO:0005524=IEA, GO:0070528=IDA, GO:0046872=IEA, GO:0007205=IEA, GO:0005829=IDA, GO:0035556=IEA, GO:0005737=IDA, GO:0016607=IDA, GO:0007186=IMP, GO:0007596=TAS, GO:0043274=IPI, GO:0070493=IDA, GO:0019933=IDA, GO:0004143=IDA, GO:0033198=IDA, GO:0033613=IPI, GO:0019900=IPI, GO:0005856=IDA} G-protein coupled receptor signaling pathway, blood coagulation, cAMP-mediated signaling, intracellular signal transduction, platelet activation, protein kinase C signaling cascade, protein kinase C-activating G-protein coupled receptor signaling pathway, response to ATP, thrombin receptor signaling pathway cytoplasm, cytoskeleton, cytosol, nuclear speck, nucleus, plasma membrane ATP binding, activating transcription factor binding, diacylglycerol kinase activity, kinase binding, metal ion binding, phospholipase binding, protein binding Human DGKZ HPA UniProtKB {GO:0004857=GO_REF:0000019, GO:0005515=PMID:17664281, GO:0005886=Reactome:REACT_19402, GO:0005730=GO_REF:0000052, GO:0030168=Reactome:REACT_798, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037, GO:0007205=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0030027=PMID:15157668, GO:0035556=GO_REF:0000002, GO:0046580=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0016477=PMID:15157668, GO:0007596=Reactome:REACT_604, GO:0004143=GO_REF:0000003} Q13574 Diacylglycerol kinase zeta protein 20120912 {GO:0004857=IEA, GO:0005515=IPI, GO:0005886=TAS, GO:0005730=IDA, GO:0030168=TAS, GO:0005634=IDA, GO:0005524=IEA, GO:0007205=IEA, GO:0046872=IEA, GO:0030027=IDA, GO:0035556=IEA, GO:0046580=IEA, GO:0005737=IEA, GO:0016477=NAS, GO:0007596=TAS, GO:0004143=IEA} blood coagulation, cell migration, intracellular signal transduction, negative regulation of Ras protein signal transduction, platelet activation, protein kinase C-activating G-protein coupled receptor signaling pathway cytoplasm, lamellipodium, nucleolus, nucleus, plasma membrane ATP binding, diacylglycerol kinase activity, enzyme inhibitor activity, metal ion binding, protein binding NOT Human DGUOK InterPro UniProtKB {GO:0046070=GO_REF:0000019, GO:0004138=PMID:8706825, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0019206=Reactome:REACT_2223, GO:0005524=GO_REF:0000002, GO:0009165=Reactome:REACT_2223, GO:0005829=GO_REF:0000019, GO:0005739=PMID:8692979, GO:0006139=GO_REF:0000002, GO:0046122=PMID:8706825, GO:0006144=Reactome:REACT_522, GO:0005759=Reactome:REACT_2223, GO:0016773=GO_REF:0000002, GO:0010977=GO_REF:0000019, GO:0043101=Reactome:REACT_1923, GO:0006468=GO_REF:0000019, GO:0008617=PMID:8692979} Q7L1W9 DGUOK protein protein 20130413 {GO:0046070=IEA, GO:0004138=IDA, GO:0055086=TAS, GO:0044281=TAS, GO:0019206=EXP, GO:0005524=IEA, GO:0009165=EXP, GO:0005829=IEA, GO:0005739=TAS, GO:0006139=IEA, GO:0046122=IDA, GO:0006144=TAS, GO:0005759=TAS, GO:0016773=IEA, GO:0010977=IEA, GO:0043101=TAS, GO:0006468=IEA, GO:0008617=TAS} dGTP metabolic process, guanosine metabolic process, negative regulation of neuron projection development, nucleobase-containing compound metabolic process, nucleobase-containing small molecule metabolic process, nucleotide biosynthetic process, protein phosphorylation, purine deoxyribonucleoside metabolic process, purine nucleobase metabolic process, purine-containing compound salvage, small molecule metabolic process cytosol, mitochondrial matrix, mitochondrion ATP binding, deoxyguanosine kinase activity, nucleoside kinase activity, phosphotransferase activity, alcohol group as acceptor Human InterPro:IPR002624 DHCR24 Reactome UniProtKB {GO:0006695=Reactome:REACT_9405, GO:0008285=GO_REF:0000019, GO:0008762=GO_REF:0000002, GO:0005783=PMID:11007892, GO:0050660=GO_REF:0000002, GO:0007265=GO_REF:0000019, GO:0005634=PMID:15577914, GO:0044281=Reactome:REACT_111217, GO:0016628=PMID:11519011, GO:0005829=GO_REF:0000019, GO:0030539=GO_REF:0000019, GO:0008104=GO_REF:0000019, GO:0050614=GO_REF:0000003, GO:0042605=PMID:15577914, GO:0009888=PMID:12457401, GO:0007050=PMID:15577914, GO:0009725=GO_REF:0000019, GO:0005856=GO_REF:0000019, GO:0043154=PMID:11007892, GO:0006979=PMID:11007892, GO:0042987=GO_REF:0000019, GO:0043066=PMID:15688385, GO:1901214=PMID:16407971, GO:0016614=GO_REF:0000002, GO:0006915=PMID:11007892, GO:0000139=GO_REF:0000039, GO:0005789=Reactome:REACT_10122, GO:0031639=GO_REF:0000019, GO:0043588=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0019899=PMID:15577914, GO:0016044=GO_REF:0000019} Q15392 Delta(24)-sterol reductase protein 20130301 {GO:0006695=TAS, GO:0008285=IEA, GO:0008762=IEA, GO:0005783=IDA, GO:0050660=IEA, GO:0007265=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0016628=IDA, GO:0005829=IEA, GO:0030539=IEA, GO:0008104=IEA, GO:0050614=IEA, GO:0042605=IPI, GO:0009888=IMP, GO:0007050=NAS, GO:0009725=IEA, GO:0005856=IEA, GO:0043154=IDA, GO:0006979=IEP, GO:0042987=IEA, GO:0043066=IDA, GO:1901214=NAS, GO:0016614=IEA, GO:0006915=NAS, GO:0000139=IEA, GO:0005789=TAS, GO:0031639=IEA, GO:0043588=ISS, GO:0016021=IEA, GO:0019899=IPI, GO:0016044=IEA} Ras protein signal transduction, amyloid precursor protein catabolic process, apoptotic process, cell cycle arrest, cellular membrane organization, cholesterol biosynthetic process, male genitalia development, negative regulation of apoptotic process, negative regulation of cell proliferation, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, plasminogen activation, protein localization, regulation of neuron death, response to hormone stimulus, response to oxidative stress, skin development, small molecule metabolic process, tissue development Golgi membrane, cytoskeleton, cytosol, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, nucleus UDP-N-acetylmuramate dehydrogenase activity, delta24-sterol reductase activity, enzyme binding, flavin adenine dinucleotide binding, oxidoreductase activity, acting on CH-OH group of donors, oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor, peptide antigen binding Human DHCR7 Reactome UniProtKB {GO:0006695=Reactome:REACT_9405, GO:0001568=GO_REF:0000019, GO:0005783=PMID:9878250, GO:0030324=GO_REF:0000019, GO:0045540=GO_REF:0000019, GO:0047598=PMID:9465114, GO:0044281=Reactome:REACT_111217, GO:0009791=GO_REF:0000019, GO:0016628=GO_REF:0000002, GO:0030154=GO_REF:0000019, GO:0043231=GO_REF:0000019, GO:0005640=PMID:9878250, GO:0035264=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0042127=GO_REF:0000019, GO:0005789=Reactome:REACT_147864, GO:0016126=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q9UBM7 7-dehydrocholesterol reductase protein 20130301 {GO:0006695=TAS, GO:0001568=IEA, GO:0005783=IDA, GO:0030324=IEA, GO:0045540=IEA, GO:0047598=IDA, GO:0044281=TAS, GO:0009791=IEA, GO:0016628=IEA, GO:0030154=IEA, GO:0043231=IEA, GO:0005640=IDA, GO:0035264=IEA, GO:0016020=IEA, GO:0042127=IEA, GO:0005789=TAS, GO:0016126=IEA, GO:0016021=IEA} blood vessel development, cell differentiation, cholesterol biosynthetic process, lung development, multicellular organism growth, post-embryonic development, regulation of cell proliferation, regulation of cholesterol biosynthetic process, small molecule metabolic process, sterol biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle, membrane, nuclear outer membrane 7-dehydrocholesterol reductase activity, oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor Human DHDDS UniProtKB UniProtKB {GO:0005515=PMID:15110773, GO:0005789=GO_REF:0000039, GO:0016765=GO_REF:0000002, GO:0006486=GO_REF:0000041} Q86SQ9 Dehydrodolichyl diphosphate synthase protein 20060208 {GO:0005515=IPI, GO:0005789=IEA, GO:0016765=IEA, GO:0006486=IEA} protein glycosylation endoplasmic reticulum membrane protein binding, transferase activity, transferring alkyl or aryl (other than methyl) groups Human UniProtKB:P61916 DHFR Reactome UniProtKB {GO:0050661=GO_REF:0000002, GO:0050999=Reactome:REACT_12389, GO:0031427=GO_REF:0000037, GO:0006767=Reactome:REACT_11238, GO:0044281=Reactome:REACT_111217, GO:0005575=GO_REF:0000015, GO:0003729=PMID:21876184, GO:0009165=GO_REF:0000029, GO:0005829=Reactome:REACT_11204, GO:0000082=Reactome:REACT_1783, GO:0000083=Reactome:REACT_683, GO:0006766=Reactome:REACT_11193, GO:0008144=PMID:12096917, GO:0046653=PMID:21876184, GO:0046654=GO_REF:0000041, GO:0046655=Reactome:REACT_11167, GO:0046209=Reactome:REACT_12508, GO:0005654=Reactome:REACT_22145, GO:0006545=GO_REF:0000029, GO:0000278=Reactome:REACT_152, GO:0006730=GO_REF:0000037, GO:0004146=PMID:21876184} P00374 Dihydrofolate reductase protein 20110817 {GO:0050661=IEA, GO:0050999=TAS, GO:0031427=IEA, GO:0006767=TAS, GO:0044281=TAS, GO:0005575=ND, GO:0003729=IDA, GO:0009165=NAS, GO:0005829=TAS, GO:0000082=TAS, GO:0000083=TAS, GO:0006766=TAS, GO:0008144=IDA, GO:0046653=IDA, GO:0046654=IEA, GO:0046655=TAS, GO:0046209=TAS, GO:0005654=TAS, GO:0006545=NAS, GO:0000278=TAS, GO:0006730=IEA, GO:0004146=IDA} G1/S transition of mitotic cell cycle, folic acid metabolic process, glycine biosynthetic process, mitotic cell cycle, nitric oxide metabolic process, nucleotide biosynthetic process, one-carbon metabolic process, regulation of nitric-oxide synthase activity, regulation of transcription involved in G1/S phase of mitotic cell cycle, response to methotrexate, small molecule metabolic process, tetrahydrofolate biosynthetic process, tetrahydrofolate metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cellular_component, cytosol, nucleoplasm NADP binding, dihydrofolate reductase activity, drug binding, mRNA binding Human DHFRL1 UniProtKB UniProtKB {GO:0005739=PMID:21876184, GO:0050661=GO_REF:0000002, GO:0005759=PMID:21876188, GO:0005743=PMID:21876188, GO:0046653=PMID:21876184, GO:0046654=GO_REF:0000041, GO:0046105=PMID:21876188, GO:0006545=GO_REF:0000002, GO:0003729=PMID:21876184, GO:0006730=GO_REF:0000037, GO:0009165=GO_REF:0000002, GO:0004146=PMID:21876188} Q86XF0 Dihydrofolate reductase, mitochondrial protein 20110916 {GO:0005739=IDA, GO:0050661=IEA, GO:0005759=IMP, GO:0005743=IMP, GO:0046653=IDA, GO:0046654=IEA, GO:0046105=IDA, GO:0006545=IEA, GO:0003729=IDA, GO:0006730=IEA, GO:0009165=IEA, GO:0004146=IMP} glycine biosynthetic process, nucleotide biosynthetic process, one-carbon metabolic process, tetrahydrofolate biosynthetic process, tetrahydrofolate metabolic process, thymidine biosynthetic process mitochondrial inner membrane, mitochondrial matrix, mitochondrion NADP binding, dihydrofolate reductase activity, mRNA binding Human DHH BHF-UCL UniProtKB {GO:0005515=PMID:19561611, GO:0005886=GO_REF:0000039, GO:0005509=PMID:19561611, GO:0007267=GO_REF:0000002, GO:0007286=GO_REF:0000019, GO:0050810=GO_REF:0000019, GO:0022402=GO_REF:0000019, GO:0005615=GO_REF:0000039, GO:0005113=GO_REF:0000019, GO:0030238=GO_REF:0000019, GO:0006508=GO_REF:0000037, GO:0033327=GO_REF:0000019, GO:0008233=GO_REF:0000037, GO:0008270=PMID:19561611} O43323 Desert hedgehog protein protein 20110727 {GO:0005515=IPI, GO:0005886=IEA, GO:0005509=IDA, GO:0007267=IEA, GO:0007286=IEA, GO:0050810=IEA, GO:0022402=IEA, GO:0005615=IEA, GO:0005113=IEA, GO:0030238=IEA, GO:0006508=IEA, GO:0033327=IEA, GO:0008233=IEA, GO:0008270=IDA} Leydig cell differentiation, cell cycle process, cell-cell signaling, male sex determination, proteolysis, regulation of steroid biosynthetic process, spermatid development extracellular space, plasma membrane calcium ion binding, patched binding, peptidase activity, protein binding, zinc ion binding Human UniProtKB:Q96QV1 DHODH Reactome UniProtKB {GO:0048039=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0044205=GO_REF:0000041, GO:0010181=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0005743=Reactome:REACT_669, GO:0006222=GO_REF:0000002, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0090140=GO_REF:0000019, GO:0031000=GO_REF:0000019, GO:0042594=GO_REF:0000019, GO:0046134=Reactome:REACT_21376, GO:0016020=GO_REF:0000002, GO:0007595=GO_REF:0000019, GO:0008144=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0004152=Reactome:REACT_669, GO:0016021=GO_REF:0000037, GO:0006207=GO_REF:0000029, GO:0006206=Reactome:REACT_957, GO:0004158=GO_REF:0000019} Q02127 Dihydroorotate dehydrogenase (quinone), mitochondrial protein 20130213 {GO:0048039=IEA, GO:0007565=IEA, GO:0043065=IEA, GO:0044205=IEA, GO:0010181=IEA, GO:0042493=IEA, GO:0005743=TAS, GO:0006222=IEA, GO:0055086=TAS, GO:0044281=TAS, GO:0090140=IEA, GO:0031000=IEA, GO:0042594=IEA, GO:0046134=TAS, GO:0016020=IEA, GO:0007595=IEA, GO:0008144=IEA, GO:0043025=IEA, GO:0004152=TAS, GO:0016021=IEA, GO:0006207=NAS, GO:0006206=TAS, GO:0004158=IEA} 'de novo' UMP biosynthetic process, 'de novo' pyrimidine nucleobase biosynthetic process, UMP biosynthetic process, female pregnancy, lactation, nucleobase-containing small molecule metabolic process, positive regulation of apoptotic process, pyrimidine nucleobase metabolic process, pyrimidine nucleoside biosynthetic process, regulation of mitochondrial fission, response to caffeine, response to drug, response to starvation, small molecule metabolic process integral to membrane, membrane, mitochondrial inner membrane, neuronal cell body FMN binding, dihydroorotate dehydrogenase activity, dihydroorotate oxidase activity, drug binding, ubiquinone binding Human DHPS InterPro UniProtKB {GO:0005515=PMID:19060904, GO:0008284=PMID:8549832, GO:0008612=GO_REF:0000002, GO:0051289=GO_REF:0000019, GO:0050983=GO_REF:0000003, GO:0044267=Reactome:REACT_17015, GO:0006412=PMID:7673224, GO:0043687=Reactome:REACT_22161, GO:0034038=Reactome:REACT_12551, GO:0005829=Reactome:REACT_12551} Q5J8M5 Migration-inducing gene 13 protein 20130413 {GO:0005515=IPI, GO:0008284=TAS, GO:0008612=IEA, GO:0051289=IEA, GO:0050983=IEA, GO:0044267=TAS, GO:0006412=TAS, GO:0043687=TAS, GO:0034038=TAS, GO:0005829=TAS} cellular protein metabolic process, deoxyhypusine biosynthetic process from spermidine, peptidyl-lysine modification to hypusine, positive regulation of cell proliferation, post-translational protein modification, protein homotetramerization, translation cytosol deoxyhypusine synthase activity, protein binding Human InterPro:IPR002773 DHRS1 LIFEdb UniProtKB {GO:0005783=GO_REF:0000054, GO:0005743=GO_REF:0000019, GO:0016491=GO_REF:0000037} Q96LJ7 Dehydrogenase/reductase SDR family member 1 protein 20100607 {GO:0005783=IDA, GO:0005743=IEA, GO:0016491=IEA} endoplasmic reticulum, mitochondrial inner membrane oxidoreductase activity Human DHRS12 UniProtKB UniProtKB {GO:0016491=GO_REF:0000037} A0PJE2 Dehydrogenase/reductase SDR family member 12 protein 20130413 {GO:0016491=IEA} oxidoreductase activity Human UniProtKB-KW:KW-0560 DHRS13 UniProtKB UniProtKB {GO:0016491=GO_REF:0000037, GO:0005576=GO_REF:0000039} Q6UX07 Dehydrogenase/reductase SDR family member 13 protein 20130413 {GO:0016491=IEA, GO:0005576=IEA} extracellular region oxidoreductase activity Human UniProtKB-SubCell:SL-0243 DHRS2 UniProtKB UniProtKB {GO:0043066=PMID:19443906, GO:0008285=PMID:1847869, GO:0004090=PMID:16685466, GO:0009636=PMID:16685466, GO:0005634=PMID:1847869, GO:0005635=PMID:11997086, GO:0005739=PMID:19443906, GO:0005737=PMID:11944995, GO:0016491=GO_REF:0000002, GO:0008207=PMID:7556196, GO:0034599=PMID:19443906, GO:0043011=PMID:11944995, GO:0055114=PMID:16685466} Q13268 Dehydrogenase/reductase SDR family member 2 protein 20080207 {GO:0043066=IMP, GO:0008285=NAS, GO:0004090=IDA, GO:0009636=IDA, GO:0005634=IDA, GO:0005635=IDA, GO:0005739=IDA, GO:0005737=IDA, GO:0016491=IEA, GO:0008207=NAS, GO:0034599=IDA, GO:0043011=IEP, GO:0055114=IDA} C21-steroid hormone metabolic process, cellular response to oxidative stress, myeloid dendritic cell differentiation, negative regulation of apoptotic process, negative regulation of cell proliferation, oxidation-reduction process, response to toxic substance cytoplasm, mitochondrion, nuclear envelope, nucleus carbonyl reductase (NADPH) activity, oxidoreductase activity Human DHRS3 InterPro UniProtKB {GO:0007603=Reactome:REACT_160125, GO:0000166=PMID:9705317, GO:0042622=Reactome:REACT_160119, GO:0042572=PMID:9705317, GO:0016491=GO_REF:0000002, GO:0009055=PMID:9705317, GO:0016021=GO_REF:0000037, GO:0052650=GO_REF:0000003, GO:0001523=Reactome:REACT_160083, GO:0007601=PMID:9705317} Q5SUY4 Short-chain dehydrogenase/reductase 3 protein 20130413 {GO:0007603=TAS, GO:0000166=TAS, GO:0042622=TAS, GO:0042572=TAS, GO:0016491=IEA, GO:0009055=TAS, GO:0016021=IEA, GO:0052650=IEA, GO:0001523=TAS, GO:0007601=TAS} phototransduction, visible light, retinoid metabolic process, retinol metabolic process, visual perception integral to membrane, photoreceptor outer segment membrane NADP-retinol dehydrogenase activity, electron carrier activity, nucleotide binding, oxidoreductase activity Human InterPro:IPR002198 DHRS4 UniProtKB UniProtKB {GO:0004090=PMID:18571493, GO:0051262=PMID:18571493, GO:0006066=PMID:18571493, GO:0005102=PMID:20178365, GO:0005634=GO_REF:0000039, GO:0005739=GO_REF:0000024, GO:0016491=GO_REF:0000002, GO:0018455=PMID:18571493, GO:0042180=PMID:18571493, GO:0008202=PMID:18571493, GO:0005778=PMID:10333503, GO:0000253=PMID:19056333, GO:0005777=PMID:17230527, GO:0055114=PMID:19442656} Q9BTZ2 Dehydrogenase/reductase SDR family member 4 protein 20120427 {GO:0004090=IDA, GO:0051262=IDA, GO:0006066=IDA, GO:0005102=IPI, GO:0005634=IEA, GO:0005739=ISS, GO:0016491=IEA, GO:0018455=IDA, GO:0042180=IDA, GO:0008202=IDA, GO:0005778=IDA, GO:0000253=IDA, GO:0005777=IDA, GO:0055114=IDA} alcohol metabolic process, cellular ketone metabolic process, oxidation-reduction process, protein tetramerization, steroid metabolic process mitochondrion, nucleus, peroxisomal membrane, peroxisome "3-keto sterol reductase activity, alcohol dehydrogenase NAD(P)+"" activity, carbonyl reductase (NADPH) activity, oxidoreductase activity, receptor binding""" Human UniProtKB:P50542 DHRS4L1 UniProtKB UniProtKB {GO:0016491=GO_REF:0000037} P0CG22 Putative dehydrogenase/reductase SDR family member 4-like 2 protein 20130413 {GO:0016491=IEA} oxidoreductase activity Human UniProtKB-KW:KW-0560 DHRS4L2 UniProtKB UniProtKB {GO:0016491=GO_REF:0000037, GO:0005576=GO_REF:0000039} Q6PKH6 Dehydrogenase/reductase SDR family member 4-like 2 protein 20130413 {GO:0016491=IEA, GO:0005576=IEA} extracellular region oxidoreductase activity Human UniProtKB-SubCell:SL-0243 DHRS7 UniProtKB UniProtKB {GO:0016491=GO_REF:0000037} Q9Y394 Dehydrogenase/reductase SDR family member 7 protein 20130413 {GO:0016491=IEA} oxidoreductase activity Human UniProtKB-KW:KW-0560 DHRS7B UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0016491=GO_REF:0000037, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037, GO:0005778=GO_REF:0000039} Q6IAN0 Dehydrogenase/reductase SDR family member 7B protein 20120517 {GO:0003674=ND, GO:0008150=ND, GO:0016491=IEA, GO:0005575=ND, GO:0016021=IEA, GO:0005778=IEA} biological_process cellular_component, integral to membrane, peroxisomal membrane molecular_function, oxidoreductase activity Human DHRSX UniProtKB UniProtKB {GO:0016491=GO_REF:0000037} Q8N5I4 Dehydrogenase/reductase SDR family member on chromosome X protein 20130413 {GO:0016491=IEA} oxidoreductase activity Human UniProtKB-KW:KW-0560 DHX15 HPA UniProtKB {GO:0008380=PMID:15146077, GO:0006397=GO_REF:0000037, GO:0008026=GO_REF:0000002, GO:0003724=PMID:7935475, GO:0005730=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0005689=PMID:15146077} O43143 Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 protein 20120912 {GO:0008380=IC, GO:0006397=IEA, GO:0008026=IEA, GO:0003724=TAS, GO:0005730=IEA, GO:0005634=IDA, GO:0003676=IEA, GO:0005524=IEA, GO:0005689=IDA} RNA splicing, mRNA processing U12-type spliceosomal complex, nucleolus, nucleus ATP binding, ATP-dependent helicase activity, RNA helicase activity, nucleic acid binding Human DHX16 InterPro UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0008026=GO_REF:0000002, GO:0003724=PMID:9547260, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000002} Q5SQH5 DEAH (Asp-Glu-Ala-His) box polypeptide 16, isoform CRA_a protein 20130413 {GO:0008380=IEA, GO:0006397=IEA, GO:0008026=IEA, GO:0003724=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0005524=IEA} RNA splicing, mRNA processing nucleolus, nucleus ATP binding, ATP-dependent helicase activity, RNA helicase activity, nucleic acid binding Human InterPro:IPR002464 DHX29 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0008026=GO_REF:0000002, GO:0003743=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q7Z478 ATP-dependent RNA helicase DHX29 protein 20130413 {GO:0005739=IEA, GO:0008026=IEA, GO:0003743=IEA, GO:0005524=IEA} mitochondrion ATP binding, ATP-dependent helicase activity, translation initiation factor activity Human Ensembl:ENSMUSP00000035244 DHX30 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0042645=PMID:18063578, GO:0005515=PMID:23455922, GO:0008026=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0003682=PMID:18063578, GO:0003723=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q7L2E3 Putative ATP-dependent RNA helicase DHX30 protein 20101115 {GO:0005739=IDA, GO:0042645=IDA, GO:0005515=IPI, GO:0008026=IEA, GO:0005737=IDA, GO:0003682=IDA, GO:0003723=IEA, GO:0003676=IEA, GO:0005524=IEA} cytoplasm, mitochondrial nucleoid, mitochondrion ATP binding, ATP-dependent helicase activity, RNA binding, chromatin binding, nucleic acid binding, protein binding Human DHX32 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0004386=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0005524=GO_REF:0000037} Q7L7V1 Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32 protein 20130413 {GO:0005739=IEA, GO:0004386=IEA, GO:0005634=IEA, GO:0005524=IEA} mitochondrion, nucleus ATP binding, helicase activity Human UniProtKB-SubCell:SL-0173 DHX33 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0045943=PMID:21930779, GO:0000182=PMID:21930779, GO:0005730=PMID:21930779, GO:0004386=GO_REF:0000002, GO:0005654=PMID:21930779, GO:0033613=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q9H6R0 Putative ATP-dependent RNA helicase DHX33 protein 20120109 {GO:0008026=IEA, GO:0045943=IDA, GO:0000182=IDA, GO:0005730=IDA, GO:0004386=IEA, GO:0005654=IDA, GO:0033613=IEA, GO:0003676=IEA, GO:0005524=IEA} positive regulation of transcription from RNA polymerase I promoter nucleolus, nucleoplasm ATP binding, ATP-dependent helicase activity, activating transcription factor binding, helicase activity, nucleic acid binding, rDNA binding Human DHX34 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q14147 Probable ATP-dependent RNA helicase DHX34 protein 20130413 {GO:0008026=IEA, GO:0003723=IEA, GO:0003676=IEA, GO:0005524=IEA} ATP binding, ATP-dependent helicase activity, RNA binding, nucleic acid binding Human UniProtKB-KW:KW-0067 DHX35 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0000398=PMID:11991638, GO:0071013=PMID:11991638, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q9H5Z1 Probable ATP-dependent RNA helicase DHX35 protein 20110302 {GO:0008026=IEA, GO:0000398=IC, GO:0071013=IDA, GO:0003676=IEA, GO:0005524=IEA} mRNA splicing, via spliceosome catalytic step 2 spliceosome ATP binding, ATP-dependent helicase activity, nucleic acid binding Human DHX36 HPA UniProtKB {GO:0005515=PMID:17932509, GO:0003725=GO_REF:0000019, GO:0008026=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0004386=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0009615=GO_REF:0000019, GO:0043330=GO_REF:0000019, GO:0005524=GO_REF:0000037} Q9H2U1 Probable ATP-dependent RNA helicase DHX36 protein 20101115 {GO:0005515=IPI, GO:0003725=IEA, GO:0008026=IEA, GO:0005737=IDA, GO:0004386=IEA, GO:0005634=IDA, GO:0003676=IEA, GO:0009615=IEA, GO:0043330=IEA, GO:0005524=IEA} response to exogenous dsRNA, response to virus cytoplasm, nucleus ATP binding, ATP-dependent helicase activity, double-stranded RNA binding, helicase activity, nucleic acid binding, protein binding Human DHX37 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q8IY37 Probable ATP-dependent RNA helicase DHX37 protein 20130413 {GO:0008026=IEA, GO:0003676=IEA, GO:0005524=IEA} ATP binding, ATP-dependent helicase activity, nucleic acid binding Human UniProtKB-KW:KW-0067 DHX38 Reactome UniProtKB {GO:0008026=GO_REF:0000002, GO:0008380=Reactome:REACT_1735, GO:0006369=Reactome:REACT_894, GO:0010467=Reactome:REACT_71, GO:0006366=Reactome:REACT_1366, GO:0031124=Reactome:REACT_1849, GO:0004386=GO_REF:0000038, GO:0005634=PMID:9524131, GO:0003676=GO_REF:0000002, GO:0071013=PMID:11991638, GO:0005524=GO_REF:0000037, GO:0006406=Reactome:REACT_1597, GO:0000398=Reactome:REACT_467, GO:0005654=Reactome:REACT_1935} Q92620 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 protein 20130213 {GO:0008026=IEA, GO:0008380=TAS, GO:0006369=TAS, GO:0010467=TAS, GO:0006366=TAS, GO:0031124=TAS, GO:0004386=IEA, GO:0005634=NAS, GO:0003676=IEA, GO:0071013=IDA, GO:0005524=IEA, GO:0006406=TAS, GO:0000398=TAS, GO:0005654=TAS} RNA splicing, gene expression, mRNA 3'-end processing, mRNA export from nucleus, mRNA splicing, via spliceosome, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter catalytic step 2 spliceosome, nucleoplasm, nucleus ATP binding, ATP-dependent helicase activity, helicase activity, nucleic acid binding Human DHX40 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0008026=GO_REF:0000002, GO:0006810=GO_REF:0000002, GO:0004386=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q8IX18 Probable ATP-dependent RNA helicase DHX40 protein 20130413 {GO:0005622=IEA, GO:0008026=IEA, GO:0006810=IEA, GO:0004386=IEA, GO:0003676=IEA, GO:0005524=IEA} transport intracellular ATP binding, ATP-dependent helicase activity, helicase activity, nucleic acid binding Human UniProtKB-KW:KW-0067 DHX57 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0004386=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q6P158 Putative ATP-dependent RNA helicase DHX57 protein 20130413 {GO:0008026=IEA, GO:0004386=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0005524=IEA} ATP binding, ATP-dependent helicase activity, helicase activity, nucleic acid binding, zinc ion binding Human UniProtKB-KW:KW-0067 DHX58 HPA UniProtKB {GO:0003725=PMID:18411269, GO:0005515=PMID:21903422, GO:0003727=PMID:18411269, GO:0004386=GO_REF:0000037, GO:1900246=GO_REF:0000024, GO:0039534=PMID:21187438, GO:1900245=GO_REF:0000024, GO:0009615=GO_REF:0000024, GO:0003677=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0051607=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0016787=GO_REF:0000002, GO:0045087=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0045088=PMID:18411269, GO:0039536=PMID:21187438, GO:0008270=PMID:19278996, GO:0032481=GO_REF:0000024, GO:0032480=PMID:21525357, GO:0045824=PMID:21525357} Q96C10 Probable ATP-dependent RNA helicase DHX58 protein 20100326 {GO:0003725=IDA, GO:0005515=IPI, GO:0003727=IDA, GO:0004386=IEA, GO:1900246=ISS, GO:0039534=IMP, GO:1900245=ISS, GO:0009615=ISS, GO:0003677=IEA, GO:0005524=IEA, GO:0051607=IEA, GO:0005737=IDA, GO:0016787=IEA, GO:0045087=IEA, GO:0019048=IEA, GO:0045088=IDA, GO:0039536=IMP, GO:0008270=IDA, GO:0032481=ISS, GO:0032480=IDA, GO:0045824=IDA} defense response to virus, innate immune response, negative regulation of MDA-5 signaling pathway, negative regulation of RIG-I signaling pathway, negative regulation of innate immune response, negative regulation of type I interferon production, positive regulation of MDA-5 signaling pathway, positive regulation of RIG-I signaling pathway, positive regulation of type I interferon production, regulation of innate immune response, response to virus, virus-host interaction cytoplasm ATP binding, DNA binding, double-stranded RNA binding, helicase activity, hydrolase activity, protein binding, single-stranded RNA binding, zinc ion binding Human DHX8 HPA UniProtKB {GO:0008380=PMID:7935475, GO:0004004=PMID:7935475, GO:0005515=PMID:16820410, GO:0008026=GO_REF:0000002, GO:0006396=PMID:7935475, GO:0000398=PMID:11991638, GO:0003723=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005681=PMID:7935475, GO:0005634=GO_REF:0000052, GO:0071013=PMID:11991638, GO:0005524=GO_REF:0000037} Q14562 ATP-dependent RNA helicase DHX8 protein 20120912 {GO:0008380=TAS, GO:0004004=TAS, GO:0005515=IPI, GO:0008026=IEA, GO:0006396=TAS, GO:0000398=IC, GO:0003723=IEA, GO:0005730=IDA, GO:0005681=TAS, GO:0005634=IDA, GO:0071013=IDA, GO:0005524=IEA} RNA processing, RNA splicing, mRNA splicing, via spliceosome catalytic step 2 spliceosome, nucleolus, nucleus, spliceosomal complex ATP binding, ATP-dependent RNA helicase activity, ATP-dependent helicase activity, RNA binding, protein binding NOT Human DHX9 BHF-UCL UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0003725=GO_REF:0000002, GO:0005515=PMID:21903422, GO:0010467=Reactome:REACT_71, GO:0003724=PMID:8690889, GO:0005813=PMID:17498979, GO:0070934=PMID:19029303, GO:0005730=GO_REF:0000039, GO:0005634=PMID:17498979, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0004004=PMID:9111062, GO:0034605=GO_REF:0000019, GO:0005737=PMID:8690889, GO:0004003=PMID:9111062, GO:0000398=Reactome:REACT_467, GO:0030529=PMID:18809582, GO:0001085=PMID:17303075, GO:0007623=GO_REF:0000019, GO:0005654=Reactome:REACT_1935, GO:0070937=PMID:19029303} Q08211 ATP-dependent RNA helicase A protein 20111118 {GO:0008380=TAS, GO:0003725=IEA, GO:0005515=IPI, GO:0010467=TAS, GO:0003724=TAS, GO:0005813=IDA, GO:0070934=IMP, GO:0005730=IEA, GO:0005634=IDA, GO:0003677=IEA, GO:0005524=IEA, GO:0004004=TAS, GO:0034605=IEA, GO:0005737=TAS, GO:0004003=TAS, GO:0000398=TAS, GO:0030529=IDA, GO:0001085=IPI, GO:0007623=IEA, GO:0005654=TAS, GO:0070937=IDA} CRD-mediated mRNA stabilization, RNA splicing, cellular response to heat, circadian rhythm, gene expression, mRNA splicing, via spliceosome CRD-mediated mRNA stability complex, centrosome, cytoplasm, nucleolus, nucleoplasm, nucleus, ribonucleoprotein complex ATP binding, ATP-dependent DNA helicase activity, ATP-dependent RNA helicase activity, DNA binding, RNA helicase activity, RNA polymerase II transcription factor binding, double-stranded RNA binding, protein binding Human UniProtKB:Q8VI67 DIABLO HPA UniProtKB {GO:0005515=PMID:21185211, GO:0008625=PMID:10950947, GO:0035631=GO_REF:0000024, GO:0008635=PMID:10929711, GO:0006919=PMID:10972280, GO:0008631=GO_REF:0000019, GO:0006915=Reactome:REACT_578, GO:0006917=GO_REF:0000002, GO:0097193=Reactome:REACT_964, GO:0005829=Reactome:REACT_2102, GO:0005739=GO_REF:0000052, GO:0005758=Reactome:REACT_1101, GO:0009898=GO_REF:0000024} Q9NR28 Diablo homolog, mitochondrial protein 20080205 {GO:0005515=IPI, GO:0008625=TAS, GO:0035631=ISS, GO:0008635=TAS, GO:0006919=TAS, GO:0008631=IEA, GO:0006915=TAS, GO:0006917=IEA, GO:0097193=TAS, GO:0005829=TAS, GO:0005739=IDA, GO:0005758=TAS, GO:0009898=ISS} activation of cysteine-type endopeptidase activity involved in apoptotic process, activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c, apoptotic process, extrinsic apoptotic signaling pathway via death domain receptors, induction of apoptosis, intrinsic apoptotic signaling pathway, intrinsic apoptotic signaling pathway in response to oxidative stress CD40 receptor complex, cytosol, internal side of plasma membrane, mitochondrial intermembrane space, mitochondrion protein binding Human DIAPH1 BHF-UCL UniProtKB {GO:0005515=PMID:22190034, GO:0072686=PMID:15123714, GO:0043005=GO_REF:0000019, GO:0030036=GO_REF:0000002, GO:0007605=GO_REF:0000037, GO:0008360=PMID:21834987, GO:0051279=PMID:15123714, GO:0005102=PMID:9360932, GO:0032886=PMID:20937854, GO:0003779=GO_REF:0000019, GO:0032587=GO_REF:0000039, GO:0031175=GO_REF:0000019, GO:0044325=PMID:15123714, GO:0005737=GO_REF:0000037, GO:0007010=PMID:21834987, GO:0030041=GO_REF:0000019, GO:0017048=GO_REF:0000019, GO:0005522=GO_REF:0000019, GO:0071420=PMID:15123714} O60610 Protein diaphanous homolog 1 protein 20120116 {GO:0005515=IPI, GO:0072686=IDA, GO:0043005=IEA, GO:0030036=IEA, GO:0007605=IEA, GO:0008360=IMP, GO:0051279=IMP, GO:0005102=NAS, GO:0032886=IMP, GO:0003779=IEA, GO:0032587=IEA, GO:0031175=IEA, GO:0044325=IPI, GO:0005737=IEA, GO:0007010=IMP, GO:0030041=IEA, GO:0017048=IEA, GO:0005522=IEA, GO:0071420=IMP} actin cytoskeleton organization, actin filament polymerization, cellular response to histamine, cytoskeleton organization, neuron projection development, regulation of cell shape, regulation of microtubule-based process, regulation of release of sequestered calcium ion into cytosol, sensory perception of sound cytoplasm, mitotic spindle, neuron projection, ruffle membrane Rho GTPase binding, actin binding, ion channel binding, profilin binding, protein binding, receptor binding Human DIAPH2 HPA UniProtKB {GO:0030036=GO_REF:0000002, GO:0005794=GO_REF:0000052, GO:0048477=GO_REF:0000037, GO:0005102=PMID:9497258, GO:0005730=GO_REF:0000052, GO:0003779=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0007292=PMID:9497258, GO:0030154=GO_REF:0000037, GO:0005829=GO_REF:0000039, GO:0043231=GO_REF:0000052, GO:0005739=GO_REF:0000052, GO:0000910=PMID:9497258, GO:0005737=GO_REF:0000052, GO:0030041=GO_REF:0000019, GO:0017048=GO_REF:0000002, GO:0005769=GO_REF:0000039} O60879 Protein diaphanous homolog 2 protein 20101115 {GO:0030036=IEA, GO:0005794=IDA, GO:0048477=IEA, GO:0005102=TAS, GO:0005730=IDA, GO:0003779=IEA, GO:0007275=IEA, GO:0007292=TAS, GO:0030154=IEA, GO:0005829=IEA, GO:0043231=IDA, GO:0005739=IDA, GO:0000910=TAS, GO:0005737=IDA, GO:0030041=IEA, GO:0017048=IEA, GO:0005769=IEA} actin cytoskeleton organization, actin filament polymerization, cell differentiation, cytokinesis, female gamete generation, multicellular organismal development, oogenesis Golgi apparatus, cytoplasm, cytosol, early endosome, intracellular membrane-bounded organelle, mitochondrion, nucleolus Rho GTPase binding, actin binding, receptor binding Human DIAPH3 UniProtKB UniProtKB {GO:0030036=GO_REF:0000002, GO:0017048=GO_REF:0000002, GO:0003779=GO_REF:0000002, GO:0005829=GO_REF:0000039} Q9NSV4 Protein diaphanous homolog 3 protein 20130413 {GO:0030036=IEA, GO:0017048=IEA, GO:0003779=IEA, GO:0005829=IEA} actin cytoskeleton organization cytosol Rho GTPase binding, actin binding Human UniProtKB-SubCell:SL-0091 DICER1 BHF-UCL UniProtKB {GO:0060576=GO_REF:0000019, GO:0005515=PMID:21903422, GO:0010467=Reactome:REACT_71, GO:0070173=GO_REF:0000019, GO:0045069=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0048536=GO_REF:0000019, GO:0031069=GO_REF:0000019, GO:0016442=PMID:15973356, GO:0051607=GO_REF:0000019, GO:0004525=PMID:12560494, GO:0000122=GO_REF:0000024, GO:0021889=GO_REF:0000019, GO:0055013=GO_REF:0000019, GO:0003725=PMID:12411504, GO:0030423=PMID:17452327, GO:2000630=GO_REF:0000019, GO:0030422=PMID:17452327, GO:0021987=GO_REF:0000019, GO:0030324=GO_REF:0000019, GO:0003723=GO_REF:0000002, GO:0021675=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_118784, GO:0071335=GO_REF:0000019, GO:0035264=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0031054=PMID:15973356, GO:0051726=GO_REF:0000019, GO:0031643=GO_REF:0000024, GO:0008026=GO_REF:0000002, GO:0006396=GO_REF:0000002, GO:0043066=GO_REF:0000019, GO:0021522=GO_REF:0000019, GO:0014040=GO_REF:0000024, GO:0006915=GO_REF:0000019, GO:0060119=GO_REF:0000019, GO:0001525=GO_REF:0000019, GO:0010070=GO_REF:0000019, GO:0051225=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0048713=GO_REF:0000019, GO:0010626=GO_REF:0000024, GO:0035198=GO_REF:0000019, GO:0035196=GO_REF:0000024, GO:0019827=GO_REF:0000019, GO:0048812=GO_REF:0000024, GO:0045664=GO_REF:0000019, GO:0032290=GO_REF:0000024, GO:0035116=GO_REF:0000019, GO:0048754=GO_REF:0000019} Q9UPY3 Endoribonuclease Dicer protein 20110316 {GO:0060576=IEA, GO:0005515=IPI, GO:0010467=TAS, GO:0070173=IEA, GO:0045069=IEA, GO:0009791=IEA, GO:0048536=IEA, GO:0031069=IEA, GO:0016442=IDA, GO:0051607=IEA, GO:0004525=IDA, GO:0000122=ISS, GO:0021889=IEA, GO:0055013=IEA, GO:0003725=IDA, GO:0030423=IMP, GO:2000630=IEA, GO:0030422=IDA, GO:0021987=IEA, GO:0030324=IEA, GO:0003723=IEA, GO:0021675=ISS, GO:0046872=IEA, GO:0005829=TAS, GO:0071335=IEA, GO:0035264=IEA, GO:0045944=IEA, GO:0031054=IDA, GO:0051726=IEA, GO:0031643=ISS, GO:0008026=IEA, GO:0006396=IEA, GO:0043066=IEA, GO:0021522=IEA, GO:0014040=ISS, GO:0006915=IEA, GO:0060119=IEA, GO:0001525=IEA, GO:0010070=IEA, GO:0051225=IEA, GO:0005524=IEA, GO:0048713=IEA, GO:0010626=ISS, GO:0035198=IEA, GO:0035196=ISS, GO:0019827=IEA, GO:0048812=ISS, GO:0045664=IEA, GO:0032290=ISS, GO:0035116=IEA, GO:0048754=IEA} RNA processing, angiogenesis, apoptotic process, branching morphogenesis of an epithelial tube, cardiac muscle cell development, cerebral cortex development, defense response to virus, embryonic hindlimb morphogenesis, gene expression, hair follicle cell proliferation, hair follicle morphogenesis, inner ear receptor cell development, intestinal epithelial cell development, lung development, multicellular organism growth, negative regulation of Schwann cell proliferation, negative regulation of apoptotic process, negative regulation of transcription from RNA polymerase II promoter, nerve development, neuron projection morphogenesis, olfactory bulb interneuron differentiation, peripheral nervous system myelin formation, positive regulation of Schwann cell differentiation, positive regulation of miRNA metabolic process, positive regulation of myelination, positive regulation of transcription from RNA polymerase II promoter, post-embryonic development, pre-miRNA processing, production of miRNAs involved in gene silencing by miRNA, production of siRNA involved in RNA interference, regulation of cell cycle, regulation of enamel mineralization, regulation of neuron differentiation, regulation of oligodendrocyte differentiation, regulation of viral genome replication, spinal cord motor neuron differentiation, spindle assembly, spleen development, stem cell maintenance, targeting of mRNA for destruction involved in RNA interference, zygote asymmetric cell division RNA-induced silencing complex, cytosol ATP binding, ATP-dependent helicase activity, RNA binding, double-stranded RNA binding, metal ion binding, miRNA binding, protein binding, ribonuclease III activity Human UniProtKB:Q4G034 DIDO1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0006915=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0006351=GO_REF:0000002} Q9BTC0 Death-inducer obliterator 1 protein 20130413 {GO:0005737=IEA, GO:0006915=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0006351=IEA} apoptotic process, transcription, DNA-dependent cytoplasm, nucleus zinc ion binding Human UniProtKB-SubCell:SL-0086 DIEXF UniProtKB UniProtKB {GO:0005730=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0005634=GO_REF:0000038} Q68CQ4 Digestive organ expansion factor homolog protein 20130413 {GO:0005730=IEA, GO:0007275=IEA, GO:0005634=IEA} multicellular organismal development nucleolus, nucleus Human UniProtKB-SubCell:SL-0188 DIMT1 UniProtKB UniProtKB {GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0052909=GO_REF:0000003, GO:0000179=GO_REF:0000002} Q9UNQ2 Probable dimethyladenosine transferase protein 20130413 {GO:0003723=IEA, GO:0005730=IEA, GO:0052909=IEA, GO:0000179=IEA} nucleolus 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity, RNA binding, rRNA (adenine-N6,N6-)-dimethyltransferase activity Human UniProtKB-SubCell:SL-0188 DIO1 Reactome UniProtKB {GO:0034641=Reactome:REACT_13, GO:0008430=GO_REF:0000019, GO:0005886=Reactome:REACT_15469, GO:0005789=GO_REF:0000039, GO:0042446=GO_REF:0000037, GO:0004800=GO_REF:0000003, GO:0006590=Reactome:REACT_15292, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037} P49895 Type I iodothyronine deiodinase protein 20130114 {GO:0034641=TAS, GO:0008430=IEA, GO:0005886=TAS, GO:0005789=IEA, GO:0042446=IEA, GO:0004800=IEA, GO:0006590=TAS, GO:0044281=TAS, GO:0016021=IEA} cellular nitrogen compound metabolic process, hormone biosynthetic process, small molecule metabolic process, thyroid hormone generation endoplasmic reticulum membrane, integral to membrane, plasma membrane selenium binding, thyroxine 5'-deiodinase activity Human DIO2 Reactome UniProtKB {GO:0005886=Reactome:REACT_15469, GO:0004800=PMID:19651899, GO:0044281=Reactome:REACT_111217, GO:0042403=PMID:19651899, GO:0034641=Reactome:REACT_13, GO:0008430=PMID:9837913, GO:0016020=PMID:9837913, GO:0001514=PMID:9837913, GO:0042446=GO_REF:0000037, GO:0006590=Reactome:REACT_15292, GO:0016021=GO_REF:0000037, GO:0042404=GO_REF:0000019, GO:0031625=PMID:19651899} Q92813 Type II iodothyronine deiodinase protein 20130114 {GO:0005886=TAS, GO:0004800=IDA, GO:0044281=TAS, GO:0042403=IDA, GO:0034641=TAS, GO:0008430=IC, GO:0016020=IC, GO:0001514=NAS, GO:0042446=IEA, GO:0006590=TAS, GO:0016021=IEA, GO:0042404=IEA, GO:0031625=IPI} cellular nitrogen compound metabolic process, hormone biosynthetic process, selenocysteine incorporation, small molecule metabolic process, thyroid hormone catabolic process, thyroid hormone generation, thyroid hormone metabolic process integral to membrane, membrane, plasma membrane selenium binding, thyroxine 5'-deiodinase activity, ubiquitin protein ligase binding Human DIO3 Reactome UniProtKB {GO:0034641=Reactome:REACT_13, GO:0008150=GO_REF:0000015, GO:0005886=Reactome:REACT_15528, GO:0004800=PMID:7593630, GO:0042446=GO_REF:0000037, GO:0006590=Reactome:REACT_15292, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0033798=GO_REF:0000003, GO:0010008=GO_REF:0000039} P55073 Type III iodothyronine deiodinase protein 20130301 {GO:0034641=TAS, GO:0008150=ND, GO:0005886=TAS, GO:0004800=NAS, GO:0042446=IEA, GO:0006590=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0033798=IEA, GO:0010008=IEA} biological_process, cellular nitrogen compound metabolic process, hormone biosynthetic process, small molecule metabolic process, thyroid hormone generation endosome membrane, integral to membrane, plasma membrane thyroxine 5'-deiodinase activity, thyroxine 5-deiodinase activity Human DIP2A IntAct UniProtKB {GO:0005515=PMID:20054002, GO:0007275=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003824=GO_REF:0000002, GO:0008134=GO_REF:0000002} Q14689 Disco-interacting protein 2 homolog A protein 20130415 {GO:0005515=IPI, GO:0007275=IEA, GO:0005634=IEA, GO:0003824=IEA, GO:0008134=IEA} multicellular organismal development nucleus catalytic activity, protein binding, transcription factor binding Human UniProtKB:Q62356 DIP2B InterPro UniProtKB {GO:0005634=GO_REF:0000002, GO:0003824=GO_REF:0000002, GO:0008134=GO_REF:0000002} Q9P265 Disco-interacting protein 2 homolog B protein 20130413 {GO:0005634=IEA, GO:0003824=IEA, GO:0008134=IEA} nucleus catalytic activity, transcription factor binding Human InterPro:IPR010506 DIP2C InterPro UniProtKB {GO:0005634=GO_REF:0000002, GO:0003824=GO_REF:0000002, GO:0008134=GO_REF:0000002} Q9Y2E4 Disco-interacting protein 2 homolog C protein 20130413 {GO:0005634=IEA, GO:0003824=IEA, GO:0008134=IEA} nucleus catalytic activity, transcription factor binding Human InterPro:IPR010506 DIRAS1 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037} O95057 GTP-binding protein Di-Ras1 protein 20130413 {GO:0005886=IEA, GO:0016020=IEA, GO:0007264=IEA, GO:0003924=IEA, GO:0005525=IEA} small GTPase mediated signal transduction membrane, plasma membrane GTP binding, GTPase activity Human UniProtKB-SubCell:SL-0039 DIRAS2 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q96HU8 GTP-binding protein Di-Ras2 protein 20130413 {GO:0005886=IEA, GO:0007264=IEA, GO:0003924=IEA, GO:0005525=IEA} small GTPase mediated signal transduction plasma membrane GTP binding, GTPase activity Human UniProtKB-SubCell:SL-0039 DIS3 IntAct UniProtKB {GO:0005515=PMID:21255825, GO:0010467=Reactome:REACT_71, GO:0016075=PMID:20368444, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=GO_REF:0000037, GO:0006364=PMID:9562621, GO:0005730=PMID:20531386, GO:0043928=Reactome:REACT_20619, GO:0004540=GO_REF:0000002, GO:0071034=PMID:19056938, GO:0000178=PMID:9562621, GO:0005829=Reactome:REACT_25297, GO:0005085=PMID:9562621, GO:0004519=PMID:20531386, GO:0000175=PMID:20531386, GO:0000176=PMID:20531386, GO:0005654=PMID:20531389, GO:0000288=Reactome:REACT_20639} Q9Y2L1 Exosome complex exonuclease RRP44 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0016075=IMP, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=IEA, GO:0006364=TAS, GO:0005730=IDA, GO:0043928=TAS, GO:0004540=IEA, GO:0071034=IMP, GO:0000178=TAS, GO:0005829=TAS, GO:0005085=IDA, GO:0004519=IMP, GO:0000175=IMP, GO:0000176=IDA, GO:0005654=IDA, GO:0000288=TAS} CUT catabolic process, RNA metabolic process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, rRNA catabolic process, rRNA processing cytosol, exosome (RNase complex), nuclear exosome (RNase complex), nucleolus, nucleoplasm 3'-5'-exoribonuclease activity, RNA binding, endonuclease activity, guanyl-nucleotide exchange factor activity, protein binding, ribonuclease activity Human UniProtKB:Q9NQT5 DIS3L HPA UniProtKB {GO:0016075=PMID:20531389, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0000175=PMID:20531386, GO:0005886=GO_REF:0000052, GO:0000177=PMID:20531386, GO:0003723=GO_REF:0000037, GO:0019899=PMID:20531386} Q8TF46 DIS3-like exonuclease 1 protein 20110516 {GO:0016075=IDA, GO:0005813=IDA, GO:0005737=IDA, GO:0000175=IMP, GO:0005886=IDA, GO:0000177=IDA, GO:0003723=IEA, GO:0019899=IPI} rRNA catabolic process centrosome, cytoplasm, cytoplasmic exosome (RNase complex), plasma membrane 3'-5'-exoribonuclease activity, RNA binding, enzyme binding Human DIS3L2 UniProtKB UniProtKB {GO:0005737=PMID:22306653, GO:0051306=PMID:22306653, GO:0007067=PMID:22306653, GO:0004527=GO_REF:0000037, GO:0008285=PMID:22306653, GO:0003723=GO_REF:0000037, GO:0004540=PMID:22306653, GO:0051301=GO_REF:0000037} Q8IYB7 DIS3-like exonuclease 2 protein 20120413 {GO:0005737=IDA, GO:0051306=IMP, GO:0007067=IMP, GO:0004527=IEA, GO:0008285=IMP, GO:0003723=IEA, GO:0004540=IDA, GO:0051301=IEA} cell division, mitosis, mitotic sister chromatid separation, negative regulation of cell proliferation cytoplasm RNA binding, exonuclease activity, ribonuclease activity Human DISC1 IntAct UniProtKB {GO:0005515=PMID:17043677, GO:0031929=GO_REF:0000019, GO:0021846=GO_REF:0000019, GO:0005813=PMID:18955030, GO:0030054=GO_REF:0000037, GO:0090128=GO_REF:0000019, GO:0005886=GO_REF:0000037, GO:0005874=GO_REF:0000037, GO:0030177=PMID:19303846, GO:0002052=PMID:19303846, GO:0000226=PMID:18955030, GO:0014069=GO_REF:0000039, GO:0005739=PMID:20880836, GO:2000060=GO_REF:0000019, GO:0045211=GO_REF:0000037, GO:0010975=GO_REF:0000019, GO:0051560=GO_REF:0000019, GO:0021799=GO_REF:0000019, GO:0001764=PMID:19502360, GO:0060070=GO_REF:0000019} Q9NRI5 Disrupted in schizophrenia 1 protein protein 20130415 {GO:0005515=IPI, GO:0031929=IEA, GO:0021846=IEA, GO:0005813=IDA, GO:0030054=IEA, GO:0090128=IEA, GO:0005886=IEA, GO:0005874=IEA, GO:0030177=IGI, GO:0002052=IGI, GO:0000226=IMP, GO:0014069=IEA, GO:0005739=IDA, GO:2000060=IEA, GO:0045211=IEA, GO:0010975=IEA, GO:0051560=IEA, GO:0021799=IEA, GO:0001764=IMP, GO:0060070=IEA} TOR signaling cascade, canonical Wnt receptor signaling pathway, cell proliferation in forebrain, cerebral cortex radially oriented cell migration, microtubule cytoskeleton organization, mitochondrial calcium ion homeostasis, neuron migration, positive regulation of Wnt receptor signaling pathway, positive regulation of neuroblast proliferation, positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process, regulation of neuron projection development, regulation of synapse maturation cell junction, centrosome, microtubule, mitochondrion, plasma membrane, postsynaptic density, postsynaptic membrane protein binding Human UniProtKB:Q9Y496 DISP1 UniProtKB UniProtKB {GO:0007368=GO_REF:0000019, GO:0007225=GO_REF:0000019, GO:0009953=GO_REF:0000019, GO:0007224=PMID:16258256, GO:0009880=GO_REF:0000019, GO:0070207=GO_REF:0000024, GO:0016323=GO_REF:0000024, GO:0015833=GO_REF:0000024, GO:0060539=PMID:20799323, GO:0008158=GO_REF:0000002, GO:0050708=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0015197=GO_REF:0000024} Q96F81 Protein dispatched homolog 1 protein 20110107 {GO:0007368=IEA, GO:0007225=IEA, GO:0009953=IEA, GO:0007224=NAS, GO:0009880=IEA, GO:0070207=ISS, GO:0016323=ISS, GO:0015833=ISS, GO:0060539=IMP, GO:0008158=IEA, GO:0050708=ISS, GO:0016021=IEA, GO:0015197=ISS} determination of left/right symmetry, diaphragm development, dorsal/ventral pattern formation, embryonic pattern specification, patched ligand maturation, peptide transport, protein homotrimerization, regulation of protein secretion, smoothened signaling pathway basolateral plasma membrane, integral to membrane hedgehog receptor activity, peptide transporter activity Human DIXDC1 IntAct UniProtKB {GO:0005515=PMID:21189423, GO:0021695=GO_REF:0000033, GO:0021869=GO_REF:0000019, GO:0090263=PMID:21189423, GO:0046330=GO_REF:0000019, GO:0030177=GO_REF:0000019, GO:0005829=PMID:19375513, GO:0005622=GO_REF:0000002, GO:0046328=GO_REF:0000033, GO:0005737=GO_REF:0000019, GO:0032956=GO_REF:0000019, GO:0021799=GO_REF:0000019, GO:0043025=GO_REF:0000033, GO:0043679=GO_REF:0000033, GO:0043010=GO_REF:0000033, GO:0004871=GO_REF:0000002, GO:0005938=GO_REF:0000033, GO:0060071=GO_REF:0000033, GO:0043015=PMID:19375513, GO:0019904=GO_REF:0000019, GO:0031435=GO_REF:0000033, GO:0007275=GO_REF:0000002, GO:0003779=GO_REF:0000037, GO:0070507=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0007049=GO_REF:0000019, GO:0045665=GO_REF:0000019, GO:0050772=GO_REF:0000033, GO:0030900=GO_REF:0000033, GO:0005925=GO_REF:0000039} Q155Q3 Dixin protein 20130415 {GO:0005515=IPI, GO:0021695=IBA, GO:0021869=IEA, GO:0090263=IDA, GO:0046330=IEA, GO:0030177=IEA, GO:0005829=IDA, GO:0005622=IEA, GO:0046328=IBA, GO:0005737=IEA, GO:0032956=IEA, GO:0021799=IEA, GO:0043025=IBA, GO:0043679=IBA, GO:0043010=IBA, GO:0004871=IEA, GO:0005938=IBA, GO:0060071=IRD, GO:0043015=IDA, GO:0019904=IEA, GO:0031435=IBA, GO:0007275=IEA, GO:0003779=IEA, GO:0070507=IEA, GO:0043234=IEA, GO:0007049=IEA, GO:0045665=IEA, GO:0050772=IBA, GO:0030900=IBA, GO:0005925=IEA} Wnt receptor signaling pathway, planar cell polarity pathway, camera-type eye development, cell cycle, cerebellar cortex development, cerebral cortex radially oriented cell migration, forebrain development, forebrain ventricular zone progenitor cell division, multicellular organismal development, negative regulation of neuron differentiation, positive regulation of JNK cascade, positive regulation of Wnt receptor signaling pathway, positive regulation of axonogenesis, positive regulation of canonical Wnt receptor signaling pathway, regulation of JNK cascade, regulation of actin cytoskeleton organization, regulation of microtubule cytoskeleton organization axon terminus, cell cortex, cytoplasm, cytosol, focal adhesion, intracellular, neuronal cell body, protein complex actin binding, gamma-tubulin binding, mitogen-activated protein kinase kinase kinase binding, protein binding, protein domain specific binding, signal transducer activity Human UniProtKB:Q60838 DKC1 HPA UniProtKB {GO:0009982=GO_REF:0000002, GO:0005515=PMID:18358808, GO:0006396=PMID:9590285, GO:0005697=PMID:12135483, GO:0015030=GO_REF:0000039, GO:0003720=PMID:12135483, GO:0008283=PMID:10591218, GO:0003723=GO_REF:0000037, GO:0006364=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0001522=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0000723=Reactome:REACT_7970, GO:0005654=Reactome:REACT_8019, GO:0007004=Reactome:REACT_7974} O60832 H/ACA ribonucleoprotein complex subunit 4 protein 20080205 {GO:0009982=IEA, GO:0005515=IPI, GO:0006396=TAS, GO:0005697=IDA, GO:0015030=IEA, GO:0003720=IDA, GO:0008283=TAS, GO:0003723=IEA, GO:0006364=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0001522=IEA, GO:0005737=IEA, GO:0000723=TAS, GO:0005654=TAS, GO:0007004=TAS} RNA processing, cell proliferation, pseudouridine synthesis, rRNA processing, telomere maintenance, telomere maintenance via telomerase Cajal body, cytoplasm, nucleolus, nucleoplasm, nucleus, telomerase holoenzyme complex RNA binding, protein binding, pseudouridine synthase activity, telomerase activity NOT Human DKK1 GOC UniProtKB {GO:0005515=PMID:17804805, GO:0090082=GO_REF:0000024, GO:0005886=PMID:16263759, GO:0042662=PMID:20559569, GO:0042663=PMID:20559569, GO:0030326=GO_REF:0000019, GO:0090244=GO_REF:0000019, GO:0005615=PMID:11742004, GO:0030514=GO_REF:0000019, GO:0031333=PMID:11448771, GO:0033137=PMID:20723538, GO:0032526=GO_REF:0000019, GO:0004871=PMID:10383463, GO:0001942=GO_REF:0000019, GO:0090090=PMID:17804805, GO:0048019=PMID:20723538, GO:0001706=GO_REF:0000019, GO:0001707=GO_REF:0000019, GO:2000726=PMID:20559569, GO:0000122=GO_REF:0000024, GO:0048642=GO_REF:0000019, GO:0000904=GO_REF:0000019, GO:0060325=GO_REF:0000019, GO:1901296=PMID:20559569, GO:1900116=PMID:20723538, GO:0002090=PMID:17804805, GO:0030900=GO_REF:0000019, GO:0008083=PMID:10383463, GO:0050750=PMID:16263759} O94907 Dickkopf-related protein 1 protein 20130413 {GO:0005515=IPI, GO:0090082=ISS, GO:0005886=IDA, GO:0042662=IDA, GO:0042663=IDA, GO:0030326=IEA, GO:0090244=IEA, GO:0005615=IDA, GO:0030514=IEA, GO:0031333=IDA, GO:0033137=IDA, GO:0032526=IEA, GO:0004871=TAS, GO:0001942=IEA, GO:0090090=IDA, GO:0048019=IDA, GO:0001706=IEA, GO:0001707=IEA, GO:2000726=IDA, GO:0000122=ISS, GO:0048642=IEA, GO:0000904=IEA, GO:0060325=IEA, GO:1901296=IDA, GO:1900116=IDA, GO:0002090=IDA, GO:0030900=IEA, GO:0008083=TAS, GO:0050750=IDA} Wnt receptor signaling pathway involved in somitogenesis, cell morphogenesis involved in differentiation, embryonic limb morphogenesis, endoderm formation, extracellular negative regulation of signal transduction, face morphogenesis, forebrain development, hair follicle development, mesoderm formation, negative regulation of BMP signaling pathway, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment, negative regulation of cardiac muscle cell differentiation, negative regulation of mesodermal cell fate specification, negative regulation of peptidyl-serine phosphorylation, negative regulation of protein complex assembly, negative regulation of skeletal muscle tissue development, negative regulation of transcription from RNA polymerase II promoter, positive regulation of heart induction by negative regulation of canonical Wnt receptor signaling pathway, regulation of endodermal cell fate specification, regulation of receptor internalization, response to retinoic acid extracellular space, plasma membrane growth factor activity, low-density lipoprotein particle receptor binding, protein binding, receptor antagonist activity, signal transducer activity Human DKK2 BHF-UCL UniProtKB {GO:0090263=PMID:12857724, GO:0030178=GO_REF:0000002, GO:0007275=GO_REF:0000037, GO:0005576=GO_REF:0000002, GO:0016055=GO_REF:0000037, GO:0090090=PMID:11742004, GO:0005615=PMID:11742004} Q9UBU2 Dickkopf-related protein 2 protein 20100930 {GO:0090263=IDA, GO:0030178=IEA, GO:0007275=IEA, GO:0005576=IEA, GO:0016055=IEA, GO:0090090=IDA, GO:0005615=IDA} Wnt receptor signaling pathway, multicellular organismal development, negative regulation of Wnt receptor signaling pathway, negative regulation of canonical Wnt receptor signaling pathway, positive regulation of canonical Wnt receptor signaling pathway extracellular region, extracellular space Human DKK3 BHF-UCL UniProtKB {GO:0030325=PMID:12844346, GO:2000065=PMID:16981135, GO:0030178=GO_REF:0000002, GO:0007275=GO_REF:0000002, GO:0005576=GO_REF:0000002, GO:0016055=GO_REF:0000037, GO:0090090=PMID:12857724, GO:0009653=PMID:10570958, GO:0005615=PMID:10570958, GO:0045892=PMID:16981135, GO:0032348=PMID:16981135} Q9UBP4 Dickkopf-related protein 3 protein 20110331 {GO:0030325=IEP, GO:2000065=IDA, GO:0030178=IEA, GO:0007275=IEA, GO:0005576=IEA, GO:0016055=IEA, GO:0090090=IDA, GO:0009653=TAS, GO:0005615=TAS, GO:0045892=IDA, GO:0032348=IDA} Wnt receptor signaling pathway, adrenal gland development, anatomical structure morphogenesis, multicellular organismal development, negative regulation of Wnt receptor signaling pathway, negative regulation of aldosterone biosynthetic process, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cortisol biosynthetic process, negative regulation of transcription, DNA-dependent extracellular region, extracellular space Human DKKL1 GOC UniProtKB {GO:0007165=PMID:10570958, GO:0045600=GO_REF:0000019, GO:0004871=PMID:10570958, GO:0009653=PMID:10570958, GO:0005615=PMID:10570958} Q9UK85 Dickkopf-like protein 1 protein 20130413 {GO:0007165=TAS, GO:0045600=IEA, GO:0004871=TAS, GO:0009653=TAS, GO:0005615=TAS} anatomical structure morphogenesis, positive regulation of fat cell differentiation, signal transduction extracellular space signal transducer activity Human DLAT Reactome UniProtKB {GO:0005515=PMID:15861126, GO:0010510=Reactome:REACT_12528, GO:0004742=PMID:3191998, GO:0006099=GO_REF:0000037, GO:0005967=PMID:3191998, GO:0006090=Reactome:REACT_2071, GO:0005759=Reactome:REACT_12543, GO:0006006=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0006085=GO_REF:0000029, GO:0045254=GO_REF:0000002} P10515 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial protein 20130213 {GO:0005515=IPI, GO:0010510=TAS, GO:0004742=NAS, GO:0006099=IEA, GO:0005967=NAS, GO:0006090=TAS, GO:0005759=TAS, GO:0006006=IEA, GO:0044281=TAS, GO:0006085=NAS, GO:0045254=IEA} acetyl-CoA biosynthetic process, glucose metabolic process, pyruvate metabolic process, regulation of acetyl-CoA biosynthetic process from pyruvate, small molecule metabolic process, tricarboxylic acid cycle mitochondrial matrix, mitochondrial pyruvate dehydrogenase complex, pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase activity, protein binding Human DLC1 GOC UniProtKB {GO:0005515=PMID:16951145, GO:0008285=PMID:17932950, GO:0030036=GO_REF:0000024, GO:0007264=Reactome:REACT_11044, GO:0035024=PMID:16951145, GO:0008360=PMID:17292327, GO:0005634=PMID:17888903, GO:0021575=GO_REF:0000024, GO:0005829=Reactome:REACT_9982, GO:0005622=GO_REF:0000002, GO:0005737=PMID:17888903, GO:0032956=PMID:17292327, GO:0048041=GO_REF:0000024, GO:0030675=PMID:17932950, GO:0042169=PMID:17190795, GO:0051056=Reactome:REACT_11051, GO:0030336=PMID:17932950, GO:0006919=PMID:17888903, GO:0035307=PMID:17292327, GO:0001843=GO_REF:0000024, GO:0006917=PMID:17888903, GO:0005100=PMID:17932950, GO:0051497=PMID:17932950, GO:0007165=GO_REF:0000002, GO:0003007=GO_REF:0000024, GO:0032321=PMID:17932950, GO:0005901=PMID:16951145, GO:0030900=GO_REF:0000024, GO:0005925=PMID:17190795} Q96QB1 Rho GTPase-activating protein 7 protein 20130413 {GO:0005515=IPI, GO:0008285=IDA, GO:0030036=ISS, GO:0007264=TAS, GO:0035024=IMP, GO:0008360=IMP, GO:0005634=IDA, GO:0021575=ISS, GO:0005829=TAS, GO:0005622=IEA, GO:0005737=IDA, GO:0032956=IMP, GO:0048041=ISS, GO:0030675=IDA, GO:0042169=IPI, GO:0051056=TAS, GO:0030336=IDA, GO:0006919=IDA, GO:0035307=IDA, GO:0001843=ISS, GO:0006917=IDA, GO:0005100=IDA, GO:0051497=IDA, GO:0007165=IEA, GO:0003007=ISS, GO:0032321=IDA, GO:0005901=IDA, GO:0030900=ISS, GO:0005925=IDA} actin cytoskeleton organization, activation of cysteine-type endopeptidase activity involved in apoptotic process, focal adhesion assembly, forebrain development, heart morphogenesis, hindbrain morphogenesis, induction of apoptosis, negative regulation of Rho protein signal transduction, negative regulation of cell migration, negative regulation of cell proliferation, negative regulation of stress fiber assembly, neural tube closure, positive regulation of Rho GTPase activity, positive regulation of protein dephosphorylation, regulation of actin cytoskeleton organization, regulation of cell shape, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction caveola, cytoplasm, cytosol, focal adhesion, intracellular, nucleus Rac GTPase activator activity, Rho GTPase activator activity, SH2 domain binding, protein binding Human DLD HPA UniProtKB {GO:0010510=Reactome:REACT_12528, GO:0006099=Reactome:REACT_1785, GO:0007369=GO_REF:0000019, GO:0043159=GO_REF:0000019, GO:0050660=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0009083=Reactome:REACT_197, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0005739=GO_REF:0000052, GO:0034641=Reactome:REACT_13, GO:0006090=Reactome:REACT_2071, GO:0005759=Reactome:REACT_12543, GO:0042391=GO_REF:0000019, GO:0006120=GO_REF:0000019, GO:0006508=GO_REF:0000019, GO:0045454=GO_REF:0000002, GO:0006554=Reactome:REACT_1298, GO:0004148=GO_REF:0000003, GO:0048240=GO_REF:0000019} P09622 Dihydrolipoyl dehydrogenase, mitochondrial protein 20120912 {GO:0010510=TAS, GO:0006099=TAS, GO:0007369=IEA, GO:0043159=IEA, GO:0050660=IEA, GO:0005730=IDA, GO:0009083=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0005739=IDA, GO:0034641=TAS, GO:0006090=TAS, GO:0005759=TAS, GO:0042391=IEA, GO:0006120=IEA, GO:0006508=IEA, GO:0045454=IEA, GO:0006554=TAS, GO:0004148=IEA, GO:0048240=IEA} branched-chain amino acid catabolic process, cell redox homeostasis, cellular nitrogen compound metabolic process, gastrulation, lysine catabolic process, mitochondrial electron transport, NADH to ubiquinone, proteolysis, pyruvate metabolic process, regulation of acetyl-CoA biosynthetic process from pyruvate, regulation of membrane potential, small molecule metabolic process, sperm capacitation, tricarboxylic acid cycle acrosomal matrix, mitochondrial matrix, mitochondrion, nucleolus, nucleus dihydrolipoyl dehydrogenase activity, flavin adenine dinucleotide binding Human DLG1 BHF-UCL UniProtKB {GO:0008092=PMID:8825652, GO:0005515=PMID:12097473, GO:0001658=GO_REF:0000019, GO:0031594=GO_REF:0000019, GO:0030054=PMID:17237226, GO:0050680=GO_REF:0000019, GO:0043268=PMID:12970345, GO:0015459=PMID:10779557, GO:0048704=GO_REF:0000019, GO:0042130=GO_REF:0000019, GO:0048608=GO_REF:0000019, GO:0016337=PMID:14699157, GO:0070830=PMID:17332497, GO:0030838=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0048745=GO_REF:0000019, GO:0045211=GO_REF:0000037, GO:0035748=GO_REF:0000019, GO:0002369=GO_REF:0000019, GO:0019901=PMID:10779557, GO:0019902=PMID:10646847, GO:0014069=GO_REF:0000039, GO:0031434=PMID:21615688, GO:0030432=GO_REF:0000019, GO:0044325=PMID:12970345, GO:0042110=GO_REF:0000019, GO:0045930=PMID:10656683, GO:0005789=GO_REF:0000039, GO:0045121=GO_REF:0000019, GO:0005923=PMID:17332497, GO:0031579=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0007093=PMID:10656683, GO:0005886=Reactome:REACT_21414, GO:0097025=PMID:17237226, GO:0007268=Reactome:REACT_13685, GO:0005634=PMID:17237226, GO:0005829=Reactome:REACT_18393, GO:0032147=GO_REF:0000019, GO:0016323=PMID:8922391, GO:0005737=PMID:17237226, GO:0008104=GO_REF:0000019, GO:0002088=GO_REF:0000019, GO:0042391=PMID:12970345, GO:0007015=PMID:14699157, GO:0004721=PMID:15302935, GO:0097016=PMID:17332497, GO:0060022=GO_REF:0000019, GO:0001772=PMID:19841189, GO:0001771=GO_REF:0000019, GO:0031253=GO_REF:0000019, GO:0004385=PMID:7937897, GO:0042982=GO_REF:0000019, GO:0008022=PMID:11274188, GO:0072659=PMID:17332497, GO:0016328=GO_REF:0000019, GO:0042383=GO_REF:0000039, GO:0032947=GO_REF:0000019, GO:0033268=GO_REF:0000019, GO:0007163=PMID:12766944, GO:0030866=PMID:14699157, GO:0019048=GO_REF:0000037, GO:0043219=GO_REF:0000019, GO:0001935=PMID:14699157} Q12959 Disks large homolog 1 protein 20120919 {GO:0008092=TAS, GO:0005515=IPI, GO:0001658=IEA, GO:0031594=IEA, GO:0030054=IDA, GO:0050680=IEA, GO:0043268=IDA, GO:0015459=NAS, GO:0048704=IEA, GO:0042130=IEA, GO:0048608=IEA, GO:0016337=IDA, GO:0070830=IDA, GO:0030838=IEA, GO:0007411=TAS, GO:0048745=IEA, GO:0045211=IEA, GO:0035748=IEA, GO:0002369=IEA, GO:0019901=IPI, GO:0019902=IPI, GO:0014069=IEA, GO:0031434=IPI, GO:0030432=IEA, GO:0044325=IPI, GO:0042110=IEA, GO:0045930=IMP, GO:0005789=IEA, GO:0045121=IEA, GO:0005923=IDA, GO:0031579=IEA, GO:0008284=IEA, GO:0007093=NAS, GO:0005886=TAS, GO:0097025=IDA, GO:0007268=TAS, GO:0005634=IDA, GO:0005829=TAS, GO:0032147=IEA, GO:0016323=IDA, GO:0005737=IDA, GO:0008104=IEA, GO:0002088=IEA, GO:0042391=IDA, GO:0007015=IDA, GO:0004721=TAS, GO:0097016=IPI, GO:0060022=IEA, GO:0001772=TAS, GO:0001771=IEA, GO:0031253=IEA, GO:0004385=TAS, GO:0042982=IEA, GO:0008022=IPI, GO:0072659=IMP, GO:0016328=IEA, GO:0042383=IEA, GO:0032947=IEA, GO:0033268=IEA, GO:0007163=TAS, GO:0030866=IDA, GO:0019048=IEA, GO:0043219=IEA, GO:0001935=IDA} T cell activation, T cell cytokine production, actin filament organization, activation of protein kinase activity, amyloid precursor protein metabolic process, axon guidance, branching involved in ureteric bud morphogenesis, cell-cell adhesion, cortical actin cytoskeleton organization, embryonic skeletal system morphogenesis, endothelial cell proliferation, establishment or maintenance of cell polarity, hard palate development, immunological synapse formation, lens development in camera-type eye, membrane raft organization, mitotic cell cycle checkpoint, negative regulation of T cell proliferation, negative regulation of epithelial cell proliferation, negative regulation of mitotic cell cycle, peristalsis, positive regulation of actin filament polymerization, positive regulation of cell proliferation, positive regulation of potassium ion transport, protein localization, protein localization to plasma membrane, regulation of membrane potential, reproductive structure development, smooth muscle tissue development, synaptic transmission, tight junction assembly, virus-host interaction MPP7-DLG1-LIN7 complex, basolateral plasma membrane, cell junction, cell projection membrane, cytoplasm, cytosol, endoplasmic reticulum membrane, immunological synapse, lateral loop, lateral plasma membrane, membrane raft, myelin sheath abaxonal region, neuromuscular junction, node of Ranvier, nucleus, plasma membrane, postsynaptic density, postsynaptic membrane, sarcolemma, tight junction L27 domain binding, cytoskeletal protein binding, guanylate kinase activity, ion channel binding, mitogen-activated protein kinase kinase binding, phosphatase binding, phosphoprotein phosphatase activity, potassium channel regulator activity, protein C-terminus binding, protein binding, protein complex scaffold, protein kinase binding Human DLG2 PINC UniProtKB {GO:0005515=PMID:19118189, GO:0030054=GO_REF:0000019, GO:0005886=GO_REF:0000037, GO:0044224=GO_REF:0000019, GO:0010923=PMID:19389623, GO:0045211=GO_REF:0000019, GO:0004385=PMID:8755482, GO:0014069=GO_REF:0000039, GO:0007268=GO_REF:0000019, GO:0019233=GO_REF:0000019} Q15700 Disks large homolog 2 protein 20030904 {GO:0005515=IPI, GO:0030054=IEA, GO:0005886=IEA, GO:0044224=IEA, GO:0010923=IDA, GO:0045211=IEA, GO:0004385=TAS, GO:0014069=IEA, GO:0007268=IEA, GO:0019233=IEA} negative regulation of phosphatase activity, sensory perception of pain, synaptic transmission cell junction, juxtaparanode region of axon, plasma membrane, postsynaptic density, postsynaptic membrane guanylate kinase activity, protein binding Human DLG3 IntAct UniProtKB {GO:0005515=PMID:19389623, GO:0001736=GO_REF:0000019, GO:0008285=PMID:9188857, GO:0005886=Reactome:REACT_21414, GO:0019902=PMID:19389623, GO:0019903=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0004385=GO_REF:0000029, GO:0045202=GO_REF:0000019, GO:0008022=GO_REF:0000019, GO:0030165=GO_REF:0000019, GO:0030426=GO_REF:0000019, GO:0045197=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0035255=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0043198=GO_REF:0000019, GO:0010923=PMID:19389623, GO:0043025=GO_REF:0000019, GO:0005923=GO_REF:0000019, GO:0031625=GO_REF:0000019} Q92796 Disks large homolog 3 protein 20130415 {GO:0005515=IPI, GO:0001736=IEA, GO:0008285=NAS, GO:0005886=TAS, GO:0019902=IDA, GO:0019903=IEA, GO:0007268=TAS, GO:0004385=NAS, GO:0045202=IEA, GO:0008022=IEA, GO:0030165=IEA, GO:0030426=IEA, GO:0045197=IEA, GO:0005737=IEA, GO:0035255=IEA, GO:0007411=TAS, GO:0043198=IEA, GO:0010923=IDA, GO:0043025=IEA, GO:0005923=IEA, GO:0031625=IEA} axon guidance, establishment of planar polarity, establishment or maintenance of epithelial cell apical/basal polarity, negative regulation of cell proliferation, negative regulation of phosphatase activity, synaptic transmission cytoplasm, dendritic shaft, growth cone, neuronal cell body, plasma membrane, synapse, tight junction PDZ domain binding, guanylate kinase activity, ionotropic glutamate receptor binding, phosphatase binding, protein C-terminus binding, protein binding, protein phosphatase binding, ubiquitin protein ligase binding Human UniProtKB:P62136 DLG4 BHF-UCL UniProtKB {GO:0005515=PMID:16767099, GO:0030054=GO_REF:0000019, GO:0008328=GO_REF:0000024, GO:2000310=GO_REF:0000024, GO:0045202=PMID:15496675, GO:0031697=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0045211=PMID:12151521, GO:0048169=GO_REF:0000019, GO:0050885=GO_REF:0000019, GO:0007612=PMID:9853749, GO:0060997=GO_REF:0000024, GO:0035641=GO_REF:0000019, GO:2000821=GO_REF:0000019, GO:2000463=GO_REF:0000024, GO:0044224=GO_REF:0000019, GO:0019903=GO_REF:0000019, GO:0014069=GO_REF:0000024, GO:0045032=GO_REF:0000024, GO:0030165=GO_REF:0000019, GO:0045031=GO_REF:0000024, GO:0071625=GO_REF:0000019, GO:0060076=GO_REF:0000024, GO:0031234=GO_REF:0000019, GO:0050806=GO_REF:0000024, GO:0035176=GO_REF:0000019, GO:0005886=GO_REF:0000024, GO:0007268=Reactome:REACT_13685, GO:0097120=GO_REF:0000024, GO:0035418=PMID:15496675, GO:0032839=GO_REF:0000024, GO:0045184=PMID:15496675, GO:0031812=GO_REF:0000024, GO:0097113=GO_REF:0000024, GO:0045944=GO_REF:0000024, GO:0032281=GO_REF:0000019, GO:0097110=GO_REF:0000024, GO:0044306=GO_REF:0000019, GO:0008022=PMID:7477295, GO:0044309=GO_REF:0000024, GO:0007399=PMID:9286702, GO:0008021=GO_REF:0000019, GO:0030666=Reactome:REACT_18393, GO:0007165=PMID:10364559, GO:0006461=PMID:15496675, GO:0001973=GO_REF:0000024, GO:0035255=GO_REF:0000024, GO:0016188=GO_REF:0000019, GO:0030863=PMID:12151521, GO:0002091=GO_REF:0000019} P78352 Disks large homolog 4 protein 20120314 {GO:0005515=IPI, GO:0030054=IEA, GO:0008328=ISS, GO:2000310=ISS, GO:0045202=IDA, GO:0031697=IEA, GO:0032403=IEA, GO:0007411=TAS, GO:0045211=IDA, GO:0048169=IEA, GO:0050885=IEA, GO:0007612=TAS, GO:0060997=ISS, GO:0035641=IEA, GO:2000821=IEA, GO:2000463=ISS, GO:0044224=IEA, GO:0019903=IEA, GO:0014069=ISS, GO:0045032=ISS, GO:0030165=IEA, GO:0045031=ISS, GO:0071625=IEA, GO:0060076=ISS, GO:0031234=IEA, GO:0050806=ISS, GO:0035176=IEA, GO:0005886=ISS, GO:0007268=TAS, GO:0097120=ISS, GO:0035418=IDA, GO:0032839=ISS, GO:0045184=IDA, GO:0031812=ISS, GO:0097113=ISS, GO:0045944=ISS, GO:0032281=IEA, GO:0097110=ISS, GO:0044306=IEA, GO:0008022=IPI, GO:0044309=ISS, GO:0007399=TAS, GO:0008021=IEA, GO:0030666=TAS, GO:0007165=TAS, GO:0006461=IDA, GO:0001973=ISS, GO:0035255=ISS, GO:0016188=IEA, GO:0030863=IDA, GO:0002091=IEA} adenosine receptor signaling pathway, alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering, axon guidance, dendritic spine morphogenesis, establishment of protein localization, learning, locomotory exploration behavior, negative regulation of receptor internalization, nervous system development, neuromuscular process controlling balance, positive regulation of excitatory postsynaptic membrane potential, positive regulation of synaptic transmission, positive regulation of transcription from RNA polymerase II promoter, protein complex assembly, protein localization to synapse, receptor localization to synapse, regulation of N-methyl-D-aspartate selective glutamate receptor activity, regulation of grooming behavior, regulation of long-term neuronal synaptic plasticity, signal transduction, social behavior, synaptic transmission, synaptic vesicle maturation, vocalization behavior alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex, cell junction, cortical cytoskeleton, dendrite cytoplasm, endocytic vesicle membrane, excitatory synapse, extrinsic to internal side of plasma membrane, ionotropic glutamate receptor complex, juxtaparanode region of axon, neuron projection terminus, neuron spine, plasma membrane, postsynaptic density, postsynaptic membrane, synapse, synaptic vesicle ADP-activated nucleotide receptor activity, ATP-activated nucleotide receptor activity, P2Y1 nucleotide receptor binding, PDZ domain binding, beta-1 adrenergic receptor binding, ionotropic glutamate receptor binding, protein C-terminus binding, protein binding, protein complex binding, protein phosphatase binding, scaffold protein binding Human UniProtKB:P31016 DLG5 PINC UniProtKB {GO:0008092=PMID:12657639, GO:0035556=PMID:12353226, GO:0007165=PMID:9738934, GO:0005737=PMID:9738934, GO:0016337=PMID:12353226, GO:0008285=PMID:9738934, GO:0005913=GO_REF:0000019, GO:0008013=PMID:12657639, GO:0005886=GO_REF:0000029, GO:0030159=PMID:12353226, GO:0042981=GO_REF:0000002} Q8TDM6 Disks large homolog 5 protein 20050308 {GO:0008092=IDA, GO:0035556=NAS, GO:0007165=TAS, GO:0005737=TAS, GO:0016337=NAS, GO:0008285=TAS, GO:0005913=IEA, GO:0008013=IDA, GO:0005886=NAS, GO:0030159=NAS, GO:0042981=IEA} cell-cell adhesion, intracellular signal transduction, negative regulation of cell proliferation, regulation of apoptotic process, signal transduction cell-cell adherens junction, cytoplasm, plasma membrane beta-catenin binding, cytoskeletal protein binding, receptor signaling complex scaffold activity Human DLGAP1 IntAct UniProtKB {GO:0005515=PMID:20936779, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0045211=GO_REF:0000037, GO:0007267=GO_REF:0000002, GO:0007268=PMID:9286858, GO:0014069=GO_REF:0000039, GO:0005575=GO_REF:0000015} O14490 Disks large-associated protein 1 protein 20130415 {GO:0005515=IPI, GO:0030054=IEA, GO:0005886=IEA, GO:0045211=IEA, GO:0007267=IEA, GO:0007268=NAS, GO:0014069=IEA, GO:0005575=ND} cell-cell signaling, synaptic transmission cell junction, cellular_component, plasma membrane, postsynaptic density, postsynaptic membrane protein binding Human UniProtKB:P62993 DLGAP2 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0045211=GO_REF:0000037, GO:0005883=PMID:10759891, GO:0007267=GO_REF:0000002, GO:0014069=GO_REF:0000039, GO:0007270=PMID:9694864} Q9P1A6 Disks large-associated protein 2 protein 20130415 {GO:0005515=IPI, GO:0030054=IEA, GO:0005886=IEA, GO:0045211=IEA, GO:0005883=NAS, GO:0007267=IEA, GO:0014069=IEA, GO:0007270=NAS} cell-cell signaling, neuron-neuron synaptic transmission cell junction, neurofilament, plasma membrane, postsynaptic density, postsynaptic membrane protein binding Human UniProtKB:P62993 DLGAP3 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0001540=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0045211=GO_REF:0000037, GO:0007267=GO_REF:0000002, GO:0014069=GO_REF:0000039} O95886 Disks large-associated protein 3 protein 20130415 {GO:0005515=IPI, GO:0001540=IEA, GO:0030054=IEA, GO:0005886=IEA, GO:0045211=IEA, GO:0007267=IEA, GO:0014069=IEA} cell-cell signaling cell junction, plasma membrane, postsynaptic density, postsynaptic membrane beta-amyloid binding, protein binding Human UniProtKB:P16333 DLGAP4 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0016020=GO_REF:0000039, GO:0007267=GO_REF:0000002, GO:0045202=GO_REF:0000019} Q9Y2H0 Disks large-associated protein 4 protein 20130415 {GO:0005515=IPI, GO:0016020=IEA, GO:0007267=IEA, GO:0045202=IEA} cell-cell signaling membrane, synapse protein binding Human UniProtKB:P62993 DLGAP5 UniProtKB UniProtKB {GO:0005515=PMID:15987997, GO:0005737=GO_REF:0000039, GO:0008283=PMID:12527899, GO:0000087=GO_REF:0000024, GO:0045842=PMID:12527899, GO:0007267=GO_REF:0000002, GO:0004721=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0031616=PMID:12527899, GO:0007079=PMID:12527899} Q15398 Disks large-associated protein 5 protein 20090424 {GO:0005515=IPI, GO:0005737=IEA, GO:0008283=NAS, GO:0000087=ISS, GO:0045842=NAS, GO:0007267=IEA, GO:0004721=ISS, GO:0005634=ISS, GO:0031616=IDA, GO:0007079=NAS} M phase of mitotic cell cycle, cell proliferation, cell-cell signaling, mitotic chromosome movement towards spindle pole, positive regulation of mitotic metaphase/anaphase transition cytoplasm, nucleus, spindle pole centrosome phosphoprotein phosphatase activity, protein binding Human UniProtKB:O14965 DLK1 Reactome UniProtKB {GO:0003674=GO_REF:0000015, GO:0045746=GO_REF:0000019, GO:0007219=Reactome:REACT_118859, GO:0048706=GO_REF:0000019, GO:0007275=PMID:8500166, GO:0016021=GO_REF:0000037, GO:0009791=GO_REF:0000019, GO:0005615=PMID:7925474, GO:0009897=GO_REF:0000019} P80370 Protein delta homolog 1 protein 20110915 {GO:0003674=ND, GO:0045746=IEA, GO:0007219=TAS, GO:0048706=IEA, GO:0007275=TAS, GO:0016021=IEA, GO:0009791=IEA, GO:0005615=TAS, GO:0009897=IEA} Notch signaling pathway, embryonic skeletal system development, multicellular organismal development, negative regulation of Notch signaling pathway, post-embryonic development external side of plasma membrane, extracellular space, integral to membrane molecular_function Human DLK2 ENSEMBL UniProtKB {GO:0045746=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0045598=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0042803=GO_REF:0000019} Q6UY11 Protein delta homolog 2 protein 20130413 {GO:0045746=IEA, GO:0046982=IEA, GO:0045598=IEA, GO:0005509=IEA, GO:0016021=IEA, GO:0042803=IEA} negative regulation of Notch signaling pathway, regulation of fat cell differentiation integral to membrane calcium ion binding, protein heterodimerization activity, protein homodimerization activity Human Ensembl:ENSMUSP00000058470 DLL1 BHF-UCL UniProtKB {GO:0005515=PMID:10079256, GO:0007368=GO_REF:0000024, GO:0007386=GO_REF:0000019, GO:0007220=Reactome:REACT_2001, GO:0005886=Reactome:REACT_160273, GO:0072014=GO_REF:0000019, GO:0001757=GO_REF:0000019, GO:0007267=GO_REF:0000019, GO:0005112=PMID:11823422, GO:0070986=GO_REF:0000019, GO:0030155=PMID:11912004, GO:0030154=PMID:11912004, GO:0001947=GO_REF:0000024, GO:0007219=Reactome:REACT_118862, GO:0045638=GO_REF:0000019, GO:0045944=GO_REF:0000024, GO:0045747=GO_REF:0000019, GO:0030097=PMID:11581320, GO:0097150=PMID:19682396, GO:0048839=GO_REF:0000019, GO:0001709=PMID:11581320, GO:0005509=GO_REF:0000002, GO:0005576=PMID:11823422, GO:0031410=GO_REF:0000019, GO:0045608=GO_REF:0000019, GO:0072070=GO_REF:0000019, GO:0005887=PMID:10079256} O00548 Delta-like protein 1 protein 20120727 {GO:0005515=IPI, GO:0007368=ISS, GO:0007386=IEA, GO:0007220=TAS, GO:0005886=TAS, GO:0072014=IEA, GO:0001757=IEA, GO:0007267=IEA, GO:0005112=IPI, GO:0070986=IEA, GO:0030155=TAS, GO:0030154=TAS, GO:0001947=ISS, GO:0007219=TAS, GO:0045638=IEA, GO:0045944=ISS, GO:0045747=IEA, GO:0030097=NAS, GO:0097150=IEP, GO:0048839=IEA, GO:0001709=NAS, GO:0005509=IEA, GO:0005576=NAS, GO:0031410=IEA, GO:0045608=IEA, GO:0072070=IEA, GO:0005887=NAS} Notch receptor processing, Notch signaling pathway, cell differentiation, cell fate determination, cell-cell signaling, compartment pattern specification, determination of left/right symmetry, heart looping, hemopoiesis, inner ear development, left/right axis specification, loop of Henle development, negative regulation of auditory receptor cell differentiation, negative regulation of myeloid cell differentiation, neuronal stem cell maintenance, positive regulation of Notch signaling pathway, positive regulation of transcription from RNA polymerase II promoter, proximal tubule development, regulation of cell adhesion, somite specification cytoplasmic vesicle, extracellular region, integral to plasma membrane, plasma membrane Notch binding, calcium ion binding, protein binding Human UniProtKB:Q61483 DLL3 UniProtKB UniProtKB {GO:0001501=PMID:10742114, GO:0048339=GO_REF:0000019, GO:0007386=GO_REF:0000019, GO:0050768=GO_REF:0000019, GO:0007219=GO_REF:0000037, GO:0001756=GO_REF:0000019, GO:0005112=PMID:10742114, GO:0007275=GO_REF:0000002, GO:0016021=PMID:10742114} Q9NYJ7 Delta-like protein 3 protein 20020806 {GO:0001501=IMP, GO:0048339=IEA, GO:0007386=IEA, GO:0050768=IEA, GO:0007219=IEA, GO:0001756=IEA, GO:0005112=NAS, GO:0007275=IEA, GO:0016021=NAS} Notch signaling pathway, compartment pattern specification, multicellular organismal development, negative regulation of neurogenesis, paraxial mesoderm development, skeletal system development, somitogenesis integral to membrane Notch binding Human DLL4 BHF-UCL UniProtKB {GO:0001569=GO_REF:0000024, GO:0035912=GO_REF:0000024, GO:0007220=Reactome:REACT_2001, GO:0005886=Reactome:REACT_160320, GO:0008015=PMID:10837024, GO:0005509=GO_REF:0000002, GO:0005112=GO_REF:0000019, GO:0001525=GO_REF:0000024, GO:0072554=GO_REF:0000019, GO:0000122=GO_REF:0000024, GO:0003208=GO_REF:0000024, GO:0003344=GO_REF:0000024, GO:0003209=GO_REF:0000024, GO:0007165=PMID:10837024, GO:0061314=GO_REF:0000024, GO:0050767=GO_REF:0000019, GO:0007219=Reactome:REACT_118862, GO:0001974=GO_REF:0000024, GO:0003222=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0043537=GO_REF:0000019} Q9NR61 Delta-like protein 4 protein 20120925 {GO:0001569=ISS, GO:0035912=ISS, GO:0007220=TAS, GO:0005886=TAS, GO:0008015=TAS, GO:0005509=IEA, GO:0005112=IEA, GO:0001525=ISS, GO:0072554=IEA, GO:0000122=ISS, GO:0003208=ISS, GO:0003344=ISS, GO:0003209=ISS, GO:0007165=TAS, GO:0061314=ISS, GO:0050767=IEA, GO:0007219=TAS, GO:0001974=ISS, GO:0003222=ISS, GO:0016021=IEA, GO:0043537=IEA} Notch receptor processing, Notch signaling involved in heart development, Notch signaling pathway, angiogenesis, blood circulation, blood vessel lumenization, blood vessel remodeling, cardiac atrium morphogenesis, cardiac ventricle morphogenesis, dorsal aorta morphogenesis, negative regulation of blood vessel endothelial cell migration, negative regulation of transcription from RNA polymerase II promoter, patterning of blood vessels, pericardium morphogenesis, regulation of neurogenesis, signal transduction, ventricular trabecula myocardium morphogenesis integral to membrane, plasma membrane Notch binding, calcium ion binding Human UniProtKB:Q9JI71 DLST UniProtKB UniProtKB {GO:0004149=GO_REF:0000003, GO:0016746=GO_REF:0000038, GO:0006099=Reactome:REACT_1785, GO:0033512=GO_REF:0000041, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0006091=PMID:8009371, GO:0043231=GO_REF:0000052, GO:0005739=GO_REF:0000052, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000052, GO:0005759=Reactome:REACT_1865, GO:0006554=Reactome:REACT_1298, GO:0045252=GO_REF:0000002, GO:0016740=GO_REF:0000038} Q86SW4 Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial protein 20130413 {GO:0004149=IEA, GO:0016746=IEA, GO:0006099=TAS, GO:0033512=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0006091=TAS, GO:0043231=IDA, GO:0005739=IDA, GO:0034641=TAS, GO:0005737=IDA, GO:0005759=TAS, GO:0006554=TAS, GO:0045252=IEA, GO:0016740=IEA} L-lysine catabolic process to acetyl-CoA via saccharopine, cellular nitrogen compound metabolic process, generation of precursor metabolites and energy, lysine catabolic process, small molecule metabolic process, tricarboxylic acid cycle cytoplasm, intracellular membrane-bounded organelle, mitochondrial matrix, mitochondrion, nucleus, oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase activity, transferase activity, transferase activity, transferring acyl groups Human UniProtKB-KW:KW-0012 DLX1 UniProtKB UniProtKB {GO:0000976=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0048706=GO_REF:0000019, GO:0007275=GO_REF:0000029, GO:0009954=GO_REF:0000019, GO:0005634=GO_REF:0000029, GO:0000122=GO_REF:0000019, GO:0003677=GO_REF:0000029, GO:0043565=GO_REF:0000002, GO:0021766=GO_REF:0000019, GO:0043524=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0048715=GO_REF:0000019, GO:0042475=GO_REF:0000019, GO:0021893=GO_REF:0000019, GO:0021882=GO_REF:0000019} P56177 Homeobox protein DLX-1 protein 20021104 {GO:0000976=IEA, GO:0003700=IEA, GO:0048706=IEA, GO:0007275=NAS, GO:0009954=IEA, GO:0005634=NAS, GO:0000122=IEA, GO:0003677=NAS, GO:0043565=IEA, GO:0021766=IEA, GO:0043524=IEA, GO:0003682=IEA, GO:0048715=IEA, GO:0042475=IEA, GO:0021893=IEA, GO:0021882=IEA} cerebral cortex GABAergic interneuron fate commitment, embryonic skeletal system development, hippocampus development, multicellular organismal development, negative regulation of neuron apoptotic process, negative regulation of oligodendrocyte differentiation, negative regulation of transcription from RNA polymerase II promoter, odontogenesis of dentin-containing tooth, proximal/distal pattern formation, regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment nucleus DNA binding, chromatin binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding Human DLX2 PINC UniProtKB {GO:0000976=GO_REF:0000002, GO:0003727=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0051216=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0009954=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0048701=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0021766=GO_REF:0000019, GO:0021772=GO_REF:0000019, GO:0007420=PMID:7590232, GO:0045944=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0048715=GO_REF:0000019, GO:0042475=GO_REF:0000019, GO:0048755=GO_REF:0000019, GO:0021893=GO_REF:0000019, GO:0021882=GO_REF:0000019} Q07687 Homeobox protein DLX-2 protein 20030904 {GO:0000976=IEA, GO:0003727=IEA, GO:0003700=IEA, GO:0051216=IEA, GO:0005634=IEA, GO:0009954=IEA, GO:0000122=IEA, GO:0048701=IEA, GO:0043565=IEA, GO:0021766=IEA, GO:0021772=IEA, GO:0007420=TAS, GO:0045944=IEA, GO:0003682=IEA, GO:0048715=IEA, GO:0042475=IEA, GO:0048755=IEA, GO:0021893=IEA, GO:0021882=IEA} brain development, branching morphogenesis of a nerve, cartilage development, cerebral cortex GABAergic interneuron fate commitment, embryonic cranial skeleton morphogenesis, hippocampus development, negative regulation of oligodendrocyte differentiation, negative regulation of transcription from RNA polymerase II promoter, odontogenesis of dentin-containing tooth, olfactory bulb development, positive regulation of transcription from RNA polymerase II promoter, proximal/distal pattern formation, regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment nucleus chromatin binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, single-stranded RNA binding, transcription regulatory region sequence-specific DNA binding Human DLX3 UniProtKB UniProtKB {GO:0000976=GO_REF:0000002, GO:0001568=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0001890=GO_REF:0000019} O60479 Homeobox protein DLX-3 protein 20130413 {GO:0000976=IEA, GO:0001568=IEA, GO:0003700=IEA, GO:0005634=IEA, GO:0001890=IEA} blood vessel development, placenta development nucleus sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding Human UniProtKB-SubCell:SL-0191 DLX4 IntAct UniProtKB {GO:0005515=PMID:21297662, GO:0043565=PMID:9073066, GO:0006355=PMID:11069021, GO:0000976=GO_REF:0000002, GO:0003700=PMID:11069021, GO:0005634=PMID:11069021, GO:0007275=GO_REF:0000037} Q92988 Homeobox protein DLX-4 protein 20130415 {GO:0005515=IPI, GO:0043565=IDA, GO:0006355=NAS, GO:0000976=IEA, GO:0003700=NAS, GO:0005634=NAS, GO:0007275=IEA} multicellular organismal development, regulation of transcription, DNA-dependent nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding Human UniProtKB:Q13485 DLX5 HPA UniProtKB {GO:0071773=GO_REF:0000024, GO:0000790=GO_REF:0000024, GO:0044212=PMID:19497851, GO:0008283=PMID:19497851, GO:0090263=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0030326=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0048646=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0030855=GO_REF:0000019, GO:0060166=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:1901522=GO_REF:0000024, GO:0050679=GO_REF:0000019, GO:0042472=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0030509=GO_REF:0000024, GO:0000978=GO_REF:0000024, GO:0001649=GO_REF:0000024, GO:0007399=PMID:7907794, GO:0045669=GO_REF:0000019, GO:0001958=GO_REF:0000024, GO:0001501=PMID:7907794, GO:0001077=GO_REF:0000024, GO:0060325=GO_REF:0000019, GO:0071837=GO_REF:0000019, GO:0045893=PMID:19497851} P56178 Homeobox protein DLX-5 protein 20080818 {GO:0071773=ISS, GO:0000790=ISS, GO:0044212=IDA, GO:0008283=IDA, GO:0090263=IEA, GO:0005634=IDA, GO:0030326=IEA, GO:0005737=IEA, GO:0048646=IEA, GO:0007411=IEA, GO:0030855=IEA, GO:0060166=IEA, GO:0060021=IEA, GO:1901522=ISS, GO:0050679=IEA, GO:0042472=IEA, GO:0005730=IDA, GO:0030509=ISS, GO:0000978=ISS, GO:0001649=ISS, GO:0007399=TAS, GO:0045669=IEA, GO:0001958=ISS, GO:0001501=TAS, GO:0001077=ISS, GO:0060325=IEA, GO:0071837=IEA, GO:0045893=IDA} BMP signaling pathway, anatomical structure formation involved in morphogenesis, axon guidance, cell proliferation, cellular response to BMP stimulus, embryonic limb morphogenesis, endochondral ossification, epithelial cell differentiation, face morphogenesis, inner ear morphogenesis, nervous system development, olfactory pit development, osteoblast differentiation, palate development, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of epithelial cell proliferation, positive regulation of osteoblast differentiation, positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus, positive regulation of transcription, DNA-dependent, skeletal system development cytoplasm, nuclear chromatin, nucleolus, nucleus HMG box domain binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, transcription regulatory region DNA binding NOT Human DLX6 PINC UniProtKB {GO:0050679=GO_REF:0000019, GO:0001501=PMID:7907794, GO:0000976=GO_REF:0000002, GO:0048646=GO_REF:0000019, GO:0042472=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0030855=GO_REF:0000019, GO:0060322=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0030326=GO_REF:0000019, GO:0007399=PMID:7907794} P56179 Homeobox protein DLX-6 protein 20030904 {GO:0050679=IEA, GO:0001501=TAS, GO:0000976=IEA, GO:0048646=IEA, GO:0042472=IEA, GO:0003700=IEA, GO:0030855=IEA, GO:0060322=IEA, GO:0060021=IEA, GO:0005634=IEA, GO:0030326=IEA, GO:0007399=TAS} anatomical structure formation involved in morphogenesis, embryonic limb morphogenesis, epithelial cell differentiation, head development, inner ear morphogenesis, nervous system development, palate development, positive regulation of epithelial cell proliferation, skeletal system development nucleus sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding Human DMAP1 UniProtKB UniProtKB {GO:0005515=PMID:15367675, GO:0001103=PMID:15367675, GO:0003714=GO_REF:0000019, GO:0005657=GO_REF:0000019, GO:0005634=PMID:15367675, GO:0000122=PMID:15367675, GO:0042993=PMID:15367675, GO:0006351=GO_REF:0000037, GO:0006306=PMID:10888872, GO:0005737=PMID:15367675, GO:0006281=GO_REF:0000002, GO:0043967=PMID:14966270, GO:0043968=PMID:14966270, GO:0003682=GO_REF:0000002, GO:0035267=PMID:14966270, GO:0006338=GO_REF:0000002, GO:0045892=PMID:10888872, GO:0040008=GO_REF:0000037} Q9NPF5 DNA methyltransferase 1-associated protein 1 protein 20111214 {GO:0005515=IPI, GO:0001103=IDA, GO:0003714=IEA, GO:0005657=IEA, GO:0005634=IDA, GO:0000122=IDA, GO:0042993=IDA, GO:0006351=IEA, GO:0006306=TAS, GO:0005737=IDA, GO:0006281=IEA, GO:0043967=IDA, GO:0043968=IDA, GO:0003682=IEA, GO:0035267=IDA, GO:0006338=IEA, GO:0045892=NAS, GO:0040008=IEA} DNA methylation, DNA repair, chromatin remodeling, histone H2A acetylation, histone H4 acetylation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of transcription factor import into nucleus, regulation of growth, transcription, DNA-dependent NuA4 histone acetyltransferase complex, cytoplasm, nucleus, replication fork RNA polymerase II repressing transcription factor binding, chromatin binding, protein binding, transcription corepressor activity Human DMBT1 GOC UniProtKB {GO:0005515=PMID:14676191, GO:0001833=GO_REF:0000019, GO:0005578=GO_REF:0000019, GO:0005576=PMID:14732920, GO:0015031=GO_REF:0000037, GO:0035375=GO_REF:0000024, GO:0051636=GO_REF:0000024, GO:0002221=PMID:12681477, GO:0005737=PMID:10485905, GO:0051607=GO_REF:0000037, GO:0030858=GO_REF:0000019, GO:0042589=GO_REF:0000024, GO:0016020=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0045087=PMID:10485905, GO:0051637=GO_REF:0000024, GO:0030855=PMID:14732920, GO:0030670=PMID:10485905, GO:0043152=PMID:14732920, GO:0019898=GO_REF:0000024, GO:0008329=PMID:12681477, GO:0005044=PMID:9288095, GO:0048306=PMID:10485905} Q9UGM3 Deleted in malignant brain tumors 1 protein protein 20130413 {GO:0005515=IPI, GO:0001833=IEA, GO:0005578=IEA, GO:0005576=TAS, GO:0015031=IEA, GO:0035375=ISS, GO:0051636=ISS, GO:0002221=TAS, GO:0005737=IDA, GO:0051607=IEA, GO:0030858=IEA, GO:0042589=ISS, GO:0016020=IEA, GO:0019048=IEA, GO:0045087=TAS, GO:0051637=ISS, GO:0030855=TAS, GO:0030670=IDA, GO:0043152=TAS, GO:0019898=ISS, GO:0008329=TAS, GO:0005044=NAS, GO:0048306=TAS} defense response to virus, epithelial cell differentiation, induction of bacterial agglutination, innate immune response, inner cell mass cell proliferation, pattern recognition receptor signaling pathway, positive regulation of epithelial cell differentiation, protein transport, virus-host interaction cytoplasm, extracellular region, extrinsic to membrane, membrane, phagocytic vesicle membrane, proteinaceous extracellular matrix, zymogen granule membrane Gram-negative bacterial cell surface binding, Gram-positive bacterial cell surface binding, calcium-dependent protein binding, pattern recognition receptor activity, protein binding, scavenger receptor activity, zymogen binding Human DMBX1 UniProtKB UniProtKB {GO:0008343=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0008344=GO_REF:0000019, GO:0003700=GO_REF:0000024, GO:0046982=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0007417=GO_REF:0000024, GO:0003677=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0042803=GO_REF:0000019, GO:0043565=GO_REF:0000024, GO:0048589=GO_REF:0000024, GO:0007420=GO_REF:0000024, GO:0045892=GO_REF:0000024} Q8NFW5 Diencephalon/mesencephalon homeobox protein 1 protein 20061106 {GO:0008343=IEA, GO:0005667=IEA, GO:0008344=IEA, GO:0003700=ISS, GO:0046982=IEA, GO:0000122=IEA, GO:0007417=ISS, GO:0003677=ISS, GO:0006351=IEA, GO:0042803=IEA, GO:0043565=ISS, GO:0048589=ISS, GO:0007420=ISS, GO:0045892=ISS} adult feeding behavior, adult locomotory behavior, brain development, central nervous system development, developmental growth, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, transcription, DNA-dependent transcription factor complex DNA binding, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:Q91ZK4 DMC1 PINC UniProtKB {GO:0005515=PMID:20729832, GO:0000781=GO_REF:0000019, GO:0000794=GO_REF:0000019, GO:0000239=GO_REF:0000019, GO:0005694=GO_REF:0000024, GO:0007286=GO_REF:0000019, GO:0007292=PMID:8602360, GO:0007283=PMID:8590282, GO:0006259=GO_REF:0000002, GO:0001556=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0001541=GO_REF:0000019, GO:0007126=PMID:8602360, GO:0007141=GO_REF:0000019, GO:0008094=GO_REF:0000002, GO:0007131=GO_REF:0000002} Q14565 Meiotic recombination protein DMC1/LIM15 homolog protein 20030904 {GO:0005515=IPI, GO:0000781=IEA, GO:0000794=IEA, GO:0000239=IEA, GO:0005694=ISS, GO:0007286=IEA, GO:0007292=TAS, GO:0007283=TAS, GO:0006259=IEA, GO:0001556=IEA, GO:0003677=IEA, GO:0005524=IEA, GO:0001541=IEA, GO:0007126=TAS, GO:0007141=IEA, GO:0008094=IEA, GO:0007131=IEA} DNA metabolic process, female gamete generation, male meiosis I, meiosis, oocyte maturation, ovarian follicle development, pachytene, reciprocal meiotic recombination, spermatid development, spermatogenesis chromosome, chromosome, telomeric region, condensed nuclear chromosome ATP binding, DNA binding, DNA-dependent ATPase activity, protein binding Human DMD UniProtKB UniProtKB {GO:0050998=PMID:7545544, GO:0005515=PMID:16000376, GO:0030055=GO_REF:0000019, GO:0030018=GO_REF:0000019, GO:0002162=PMID:7592992, GO:0045202=GO_REF:0000019, GO:0060857=GO_REF:0000019, GO:0014819=PMID:19198614, GO:0060048=PMID:19027585, GO:0046716=GO_REF:0000019, GO:0005829=Reactome:REACT_17057, GO:0021629=GO_REF:0000019, GO:0048747=GO_REF:0000019, GO:0016010=PMID:17993586, GO:0045211=GO_REF:0000039, GO:0086001=PMID:20080623, GO:0005856=GO_REF:0000039, GO:0008307=PMID:16000376, GO:0051647=GO_REF:0000019, GO:0044306=GO_REF:0000019, GO:0006355=GO_REF:0000019, GO:0030049=Reactome:REACT_16969, GO:0009986=PMID:10867799, GO:0005509=GO_REF:0000002, GO:0043043=PMID:16000376, GO:0010881=PMID:20080623, GO:0003779=GO_REF:0000038, GO:0045213=GO_REF:0000019, GO:0014904=GO_REF:0000019, GO:0014809=PMID:19198614, GO:0042383=PMID:7545544, GO:0043234=PMID:18468998, GO:0007517=PMID:1824797, GO:0002027=PMID:19027585, GO:0008065=GO_REF:0000019, GO:0005200=PMID:3282674, GO:0043034=PMID:16000376, GO:0045121=GO_REF:0000019, GO:0008270=GO_REF:0000002} Q4G0X0 Dystrophin protein 20130413 {GO:0050998=ISS, GO:0005515=IPI, GO:0030055=IEA, GO:0030018=IEA, GO:0002162=IPI, GO:0045202=IEA, GO:0060857=IEA, GO:0014819=ISS, GO:0060048=IMP, GO:0046716=IEA, GO:0005829=TAS, GO:0021629=IEA, GO:0048747=IEA, GO:0016010=IDA, GO:0045211=IEA, GO:0086001=ISS, GO:0005856=IEA, GO:0008307=IDA, GO:0051647=IEA, GO:0044306=IEA, GO:0006355=IEA, GO:0030049=TAS, GO:0009986=IDA, GO:0005509=IEA, GO:0043043=IDA, GO:0010881=ISS, GO:0003779=IEA, GO:0045213=IEA, GO:0014904=IEA, GO:0014809=ISS, GO:0042383=IDA, GO:0043234=IDA, GO:0007517=NAS, GO:0002027=IMP, GO:0008065=IEA, GO:0005200=TAS, GO:0043034=IDA, GO:0045121=IEA, GO:0008270=IEA} cardiac muscle contraction, establishment of blood-nerve barrier, establishment of glial blood-brain barrier, muscle cell homeostasis, muscle fiber development, muscle filament sliding, muscle organ development, myotube cell development, neurotransmitter receptor metabolic process, nucleus localization, olfactory nerve structural organization, peptide biosynthetic process, regulation of cardiac muscle cell action potential, regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion, regulation of heart rate, regulation of skeletal muscle contraction, regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion, regulation of transcription, DNA-dependent Z disc, cell surface, cell-substrate junction, costamere, cytoskeleton, cytosol, dystrophin-associated glycoprotein complex, membrane raft, neuron projection terminus, postsynaptic membrane, protein complex, sarcolemma, synapse actin binding, calcium ion binding, dystroglycan binding, nitric-oxide synthase binding, protein binding, structural constituent of cytoskeleton, structural constituent of muscle, zinc ion binding Human UniProtKB-KW:KW-0009 DMKN ENSEMBL UniProtKB {GO:0005615=GO_REF:0000019} Q6E0U4 Dermokine protein 20130413 {GO:0005615=IEA} extracellular space Human Ensembl:ENSMUSP00000129031 DMP1 HPA UniProtKB {GO:0005737=GO_REF:0000039, GO:0005178=PMID:8509401, GO:0001503=GO_REF:0000002, GO:0030198=GO_REF:0000019, GO:0005509=PMID:8509401, GO:0010811=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005578=GO_REF:0000039, GO:0050840=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0031214=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q13316 Dentin matrix acidic phosphoprotein 1 protein 20110516 {GO:0005737=IEA, GO:0005178=TAS, GO:0001503=IEA, GO:0030198=IEA, GO:0005509=TAS, GO:0010811=IEA, GO:0005730=IDA, GO:0005578=IEA, GO:0050840=IEA, GO:0005634=IDA, GO:0031214=IEA, GO:0043231=IDA} biomineral tissue development, extracellular matrix organization, ossification, positive regulation of cell-substrate adhesion cytoplasm, intracellular membrane-bounded organelle, nucleolus, nucleus, proteinaceous extracellular matrix calcium ion binding, extracellular matrix binding, integrin binding Human DMPK IntAct UniProtKB {GO:0005515=PMID:15598648, GO:0031965=GO_REF:0000024, GO:0005886=GO_REF:0000024, GO:0031532=GO_REF:0000002, GO:0008016=PMID:15598648, GO:0006874=GO_REF:0000024, GO:0033017=GO_REF:0000024, GO:0010830=GO_REF:0000024, GO:0005524=PMID:10913253, GO:0046872=GO_REF:0000037, GO:0005829=GO_REF:0000024, GO:0014722=GO_REF:0000019, GO:0005640=GO_REF:0000039, GO:0051823=GO_REF:0000019, GO:0004672=GO_REF:0000002, GO:0017020=PMID:11287000, GO:0004674=PMID:11287000, GO:0002028=GO_REF:0000019, GO:0005789=GO_REF:0000024, GO:0010657=PMID:18729234, GO:0006998=PMID:21949239, GO:0006468=PMID:11287000, GO:0031307=PMID:15684391, GO:0014853=GO_REF:0000019} Q09013 Myotonin-protein kinase protein 20130415 {GO:0005515=IPI, GO:0031965=ISS, GO:0005886=ISS, GO:0031532=IEA, GO:0008016=IDA, GO:0006874=ISS, GO:0033017=ISS, GO:0010830=ISS, GO:0005524=IDA, GO:0046872=IEA, GO:0005829=ISS, GO:0014722=IEA, GO:0005640=IEA, GO:0051823=IEA, GO:0004672=IEA, GO:0017020=IDA, GO:0004674=IDA, GO:0002028=IEA, GO:0005789=ISS, GO:0010657=IDA, GO:0006998=IMP, GO:0006468=IDA, GO:0031307=IDA, GO:0014853=IEA} actin cytoskeleton reorganization, cellular calcium ion homeostasis, muscle cell apoptotic process, nuclear envelope organization, protein phosphorylation, regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction, regulation of heart contraction, regulation of myotube differentiation, regulation of skeletal muscle contraction by calcium ion signaling, regulation of sodium ion transport, regulation of synapse structural plasticity cytosol, endoplasmic reticulum membrane, integral to mitochondrial outer membrane, nuclear membrane, nuclear outer membrane, plasma membrane, sarcoplasmic reticulum membrane ATP binding, metal ion binding, myosin phosphatase regulator activity, protein binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB:P26678 DMRT1 PINC UniProtKB {GO:0000987=GO_REF:0000024, GO:0008354=GO_REF:0000019, GO:0003700=PMID:10332030, GO:0046661=GO_REF:0000024, GO:0002176=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0045840=GO_REF:0000024, GO:0000122=GO_REF:0000024, GO:0007283=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0007530=PMID:10332030, GO:0035556=GO_REF:0000019, GO:0000902=GO_REF:0000019, GO:0060008=GO_REF:0000024, GO:0030238=GO_REF:0000024, GO:0045944=GO_REF:0000024, GO:0045835=GO_REF:0000024, GO:0008584=PMID:10332030} Q9Y5R6 Doublesex- and mab-3-related transcription factor 1 protein 20030904 {GO:0000987=ISS, GO:0008354=IEA, GO:0003700=TAS, GO:0046661=ISS, GO:0002176=ISS, GO:0005634=ISS, GO:0045840=ISS, GO:0000122=ISS, GO:0007283=IEA, GO:0046872=IEA, GO:0006351=IEA, GO:0007530=TAS, GO:0035556=IEA, GO:0000902=IEA, GO:0060008=ISS, GO:0030238=ISS, GO:0045944=ISS, GO:0045835=ISS, GO:0008584=TAS} Sertoli cell differentiation, cell morphogenesis, germ cell migration, intracellular signal transduction, male germ cell proliferation, male gonad development, male sex determination, male sex differentiation, negative regulation of meiosis, negative regulation of transcription from RNA polymerase II promoter, positive regulation of mitosis, positive regulation of transcription from RNA polymerase II promoter, sex determination, spermatogenesis, transcription, DNA-dependent nucleus core promoter proximal region sequence-specific DNA binding, metal ion binding, sequence-specific DNA binding transcription factor activity Human DMRT2 PINC UniProtKB {GO:0043565=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0003700=PMID:10332030, GO:0005634=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0008584=PMID:10332030, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0007530=PMID:10332030} Q9Y5R5 Doublesex- and mab-3-related transcription factor 2 protein 20030904 {GO:0043565=IEA, GO:0003674=ND, GO:0008150=ND, GO:0003700=TAS, GO:0005634=IEA, GO:0005575=ND, GO:0008584=TAS, GO:0046872=IEA, GO:0006351=IEA, GO:0007530=TAS} biological_process, male gonad development, sex determination, transcription, DNA-dependent cellular_component, nucleus metal ion binding, molecular_function, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human DMRTA1 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0007548=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q5VZB9 Doublesex- and mab-3-related transcription factor A1 protein 20130413 {GO:0043565=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0007548=IEA, GO:0046872=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, sex differentiation, transcription, DNA-dependent nucleus metal ion binding, sequence-specific DNA binding Human UniProtKB-SubCell:SL-0191 DMRTB1 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0007548=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96MA1 Doublesex- and mab-3-related transcription factor B1 protein 20130413 {GO:0043565=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0007548=IEA, GO:0046872=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, sex differentiation, transcription, DNA-dependent nucleus metal ion binding, sequence-specific DNA binding Human UniProtKB-SubCell:SL-0191 DMRTC2 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0007548=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0046872=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8IXT2 Doublesex- and mab-3-related transcription factor C2 protein 20130413 {GO:0043565=IEA, GO:0006355=IEA, GO:0007548=IEA, GO:0005634=IEA, GO:0046872=IEA, GO:0030154=IEA, GO:0006351=IEA} cell differentiation, regulation of transcription, DNA-dependent, sex differentiation, transcription, DNA-dependent nucleus metal ion binding, sequence-specific DNA binding Human UniProtKB-SubCell:SL-0191 DMTF1 HPA UniProtKB {GO:0006355=PMID:10095122, GO:0007049=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0003700=PMID:10095122, GO:0003682=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9Y222 Cyclin-D-binding Myb-like transcription factor 1 protein 20100326 {GO:0006355=NAS, GO:0007049=IEA, GO:0005737=IDA, GO:0003700=NAS, GO:0003682=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA} cell cycle, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleolus, nucleus DNA binding, chromatin binding, sequence-specific DNA binding transcription factor activity Human DMWD UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0007126=GO_REF:0000029, GO:0005575=GO_REF:0000015} Q09019 Dystrophia myotonica WD repeat-containing protein protein 20061026 {GO:0003674=ND, GO:0007126=NAS, GO:0005575=ND} meiosis cellular_component molecular_function Human DMXL1 null null {} null null null null {} null null null DMXL2 MGI UniProtKB {GO:0017137=PMID:11809763, GO:0030054=GO_REF:0000037, GO:0030672=GO_REF:0000039, GO:0008021=PMID:11809763} Q8TDJ6 DmX-like protein 2 protein 20060111 {GO:0017137=IDA, GO:0030054=IEA, GO:0030672=IEA, GO:0008021=IDA} cell junction, synaptic vesicle, synaptic vesicle membrane Rab GTPase binding Human DNA2 GOC UniProtKB {GO:0042645=PMID:19487465, GO:0005515=PMID:21325134, GO:0006200=PMID:18995831, GO:0016890=PMID:18995831, GO:0005760=PMID:18995831, GO:0033567=PMID:22570407, GO:0005634=PMID:19487465, GO:0046872=GO_REF:0000037, GO:0000084=Reactome:REACT_899, GO:0006271=Reactome:REACT_932, GO:0000723=Reactome:REACT_7970, GO:0000722=Reactome:REACT_8027, GO:0043504=PMID:19487465, GO:0032508=PMID:16595800, GO:0016887=PMID:18995831, GO:0000729=PMID:21325134, GO:0043142=PMID:16595800, GO:0051539=GO_REF:0000037, GO:0045740=PMID:18995831, GO:0004386=PMID:18995831, GO:0005524=GO_REF:0000037, GO:0003677=PMID:20019387, GO:0003678=PMID:16595800, GO:0006260=PMID:22570476, GO:0004518=PMID:21325134, GO:0006284=PMID:18995831, GO:0000076=PMID:22570476, GO:0043139=PMID:20019387, GO:0005654=Reactome:REACT_8015, GO:0043137=PMID:18995831, GO:0017108=PMID:20019387, GO:0000278=Reactome:REACT_152, GO:0006264=PMID:19487465, GO:0032201=Reactome:REACT_7961} P51530 DNA replication ATP-dependent helicase/nuclease DNA2 protein 20130413 {GO:0042645=IDA, GO:0005515=IPI, GO:0006200=TAS, GO:0016890=IDA, GO:0005760=IDA, GO:0033567=IDA, GO:0005634=IDA, GO:0046872=IEA, GO:0000084=TAS, GO:0006271=TAS, GO:0000723=TAS, GO:0000722=TAS, GO:0043504=IDA, GO:0032508=IDA, GO:0016887=TAS, GO:0000729=IDA, GO:0043142=IDA, GO:0051539=IEA, GO:0045740=IDA, GO:0004386=TAS, GO:0005524=IEA, GO:0003677=IDA, GO:0003678=IDA, GO:0006260=IMP, GO:0004518=IDA, GO:0006284=IDA, GO:0000076=IMP, GO:0043139=IDA, GO:0005654=TAS, GO:0043137=IDA, GO:0017108=IDA, GO:0000278=TAS, GO:0006264=IDA, GO:0032201=TAS} ATP catabolic process, DNA double-strand break processing, DNA duplex unwinding, DNA replication, DNA replication checkpoint, DNA replication, Okazaki fragment processing, DNA replication, removal of RNA primer, DNA strand elongation involved in DNA replication, S phase of mitotic cell cycle, base-excision repair, mitochondrial DNA repair, mitochondrial DNA replication, mitotic cell cycle, positive regulation of DNA replication, telomere maintenance, telomere maintenance via recombination, telomere maintenance via semi-conservative replication gamma DNA polymerase complex, mitochondrial nucleoid, nucleoplasm, nucleus 4 iron, 4 sulfur cluster binding, 5'-3' DNA helicase activity, 5'-flap endonuclease activity, ATP binding, ATPase activity, DNA binding, DNA helicase activity, helicase activity, metal ion binding, nuclease activity, protein binding, single-stranded DNA-dependent ATPase activity, site-specific endodeoxyribonuclease activity, specific for altered base Human DNAAF1 HPA UniProtKB {GO:0036159=PMID:19944400, GO:0003356=PMID:19944400, GO:0035469=PMID:19944405, GO:0005886=GO_REF:0000052, GO:0030324=PMID:19944405, GO:0071910=PMID:19944405, GO:0005634=GO_REF:0000052, GO:0003341=PMID:19944405, GO:0035085=PMID:18385425, GO:0070286=PMID:19944400, GO:0044458=PMID:19944405, GO:0060287=PMID:19944405, GO:0001947=PMID:19944405, GO:0005737=GO_REF:0000052, GO:0000922=GO_REF:0000039, GO:0045502=PMID:18385425, GO:0060972=PMID:19944400, GO:0060271=PMID:18385425, GO:0036158=PMID:19944400, GO:0071907=PMID:19944405} Q8NEP3 Dynein assembly factor 1, axonemal protein 20111111 {GO:0036159=IMP, GO:0003356=IMP, GO:0035469=IMP, GO:0005886=IDA, GO:0030324=IMP, GO:0071910=IMP, GO:0005634=IDA, GO:0003341=IMP, GO:0035085=IDA, GO:0070286=IMP, GO:0044458=IMP, GO:0060287=IC, GO:0001947=IMP, GO:0005737=IDA, GO:0000922=IEA, GO:0045502=IMP, GO:0060972=IMP, GO:0060271=IMP, GO:0036158=IMP, GO:0071907=IMP} axonemal dynein complex assembly, cilium morphogenesis, cilium movement, determination of digestive tract left/right asymmetry, determination of liver left/right asymmetry, determination of pancreatic left/right asymmetry, epithelial cilium movement involved in determination of left/right asymmetry, heart looping, inner dynein arm assembly, left/right pattern formation, lung development, motile cilium assembly, outer dynein arm assembly, regulation of cilium beat frequency cilium axoneme, cytoplasm, nucleus, plasma membrane, spindle pole dynein binding Human DNAAF2 UniProtKB UniProtKB {GO:0060286=PMID:19052621, GO:0005737=PMID:19052621, GO:0060285=PMID:19052621, GO:0032526=GO_REF:0000019, GO:0070286=PMID:19052621} Q9NVR5 Protein kintoun protein 20090330 {GO:0060286=IMP, GO:0005737=IDA, GO:0060285=IMP, GO:0032526=IEA, GO:0070286=IMP} axonemal dynein complex assembly, ciliary cell motility, flagellar cell motility, response to retinoic acid cytoplasm Human DNAH1 UniProtKB UniProtKB {GO:0030286=PMID:8812413, GO:0001539=PMID:9373155, GO:0005874=GO_REF:0000037, GO:0005858=PMID:9373155, GO:0035085=GO_REF:0000039, GO:0003777=PMID:9373155, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002, GO:0009612=PMID:8812413, GO:0007018=GO_REF:0000019} Q9P2D7 Dynein heavy chain 1, axonemal protein 20090811 {GO:0030286=NAS, GO:0001539=NAS, GO:0005874=IEA, GO:0005858=NAS, GO:0035085=IEA, GO:0003777=NAS, GO:0005524=IEA, GO:0016887=IEA, GO:0009612=NAS, GO:0007018=IEA} ciliary or flagellar motility, microtubule-based movement, response to mechanical stimulus axonemal dynein complex, cilium axoneme, dynein complex, microtubule ATP binding, ATPase activity, microtubule motor activity Human DNAH11 UniProtKB UniProtKB {GO:0007368=GO_REF:0000019, GO:0001539=GO_REF:0000019, GO:0005874=GO_REF:0000037, GO:0005858=GO_REF:0000029, GO:0035085=GO_REF:0000039, GO:0003777=GO_REF:0000029, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002, GO:0007018=GO_REF:0000002} Q96DT5 Dynein heavy chain 11, axonemal protein 20031120 {GO:0007368=IEA, GO:0001539=IEA, GO:0005874=IEA, GO:0005858=NAS, GO:0035085=IEA, GO:0003777=NAS, GO:0005524=IEA, GO:0016887=IEA, GO:0007018=IEA} ciliary or flagellar motility, determination of left/right symmetry, microtubule-based movement axonemal dynein complex, cilium axoneme, microtubule ATP binding, ATPase activity, microtubule motor activity Human DNAH14 UniProtKB UniProtKB {GO:0030286=GO_REF:0000037, GO:0005874=GO_REF:0000037, GO:0035085=GO_REF:0000039, GO:0003777=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0007018=GO_REF:0000002} Q0VDD8 Dynein heavy chain 14, axonemal protein 20130413 {GO:0030286=IEA, GO:0005874=IEA, GO:0035085=IEA, GO:0003777=IEA, GO:0005524=IEA, GO:0007018=IEA} microtubule-based movement cilium axoneme, dynein complex, microtubule ATP binding, microtubule motor activity Human UniProtKB-SubCell:SL-0304 DNAH2 UniProtKB UniProtKB {GO:0001539=PMID:9256245, GO:0005874=GO_REF:0000037, GO:0005858=PMID:9256245, GO:0035085=GO_REF:0000039, GO:0003777=PMID:9256245, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002, GO:0007018=GO_REF:0000002} Q9P225 Dynein heavy chain 2, axonemal protein 20010911 {GO:0001539=NAS, GO:0005874=IEA, GO:0005858=NAS, GO:0035085=IEA, GO:0003777=NAS, GO:0005524=IEA, GO:0016887=IEA, GO:0007018=IEA} ciliary or flagellar motility, microtubule-based movement axonemal dynein complex, cilium axoneme, microtubule ATP binding, ATPase activity, microtubule motor activity Human DNAH3 UniProtKB UniProtKB {GO:0001539=PMID:9256245, GO:0005874=GO_REF:0000037, GO:0005858=PMID:9256245, GO:0003777=PMID:9256245, GO:0035085=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002, GO:0007018=GO_REF:0000002} Q8TD57 Dynein heavy chain 3, axonemal protein 20010911 {GO:0001539=NAS, GO:0005874=IEA, GO:0005858=NAS, GO:0003777=NAS, GO:0035085=IEA, GO:0005524=IEA, GO:0016887=IEA, GO:0007018=IEA} ciliary or flagellar motility, microtubule-based movement axonemal dynein complex, cilium axoneme, microtubule ATP binding, ATPase activity, microtubule motor activity Human DNAH5 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0001539=GO_REF:0000019, GO:0005874=GO_REF:0000037, GO:0005858=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0003777=PMID:8812413, GO:0035085=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002, GO:0007018=GO_REF:0000002} Q8TE73 Dynein heavy chain 5, axonemal protein 20061026 {GO:0008150=ND, GO:0001539=IEA, GO:0005874=IEA, GO:0005858=IEA, GO:0005575=ND, GO:0003777=NAS, GO:0035085=IEA, GO:0005524=IEA, GO:0016887=IEA, GO:0007018=IEA} biological_process, ciliary or flagellar motility, microtubule-based movement axonemal dynein complex, cellular_component, cilium axoneme, microtubule ATP binding, ATPase activity, microtubule motor activity Human DNAH6 UniProtKB UniProtKB {GO:0001539=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0005858=GO_REF:0000002, GO:0003777=PMID:8812413, GO:0035085=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002, GO:0007018=GO_REF:0000002} Q9C0G6 Dynein heavy chain 6, axonemal protein 20090811 {GO:0001539=IEA, GO:0005874=IEA, GO:0005858=IEA, GO:0003777=NAS, GO:0035085=IEA, GO:0005524=IEA, GO:0016887=IEA, GO:0007018=IEA} ciliary or flagellar motility, microtubule-based movement axonemal dynein complex, cilium axoneme, microtubule ATP binding, ATPase activity, microtubule motor activity Human DNAH7 MGI UniProtKB {GO:0005929=PMID:11877439, GO:0001539=PMID:9373155, GO:0005874=GO_REF:0000037, GO:0005509=GO_REF:0000002, GO:0005858=PMID:9373155, GO:0003777=PMID:9373155, GO:0035085=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0016887=GO_REF:0000002, GO:0007018=GO_REF:0000002} Q8WXX0 Dynein heavy chain 7, axonemal protein 20060111 {GO:0005929=IDA, GO:0001539=NAS, GO:0005874=IEA, GO:0005509=IEA, GO:0005858=NAS, GO:0003777=NAS, GO:0035085=IEA, GO:0005524=IEA, GO:0016887=IEA, GO:0007018=IEA} ciliary or flagellar motility, microtubule-based movement axonemal dynein complex, cilium, cilium axoneme, microtubule ATP binding, ATPase activity, calcium ion binding, microtubule motor activity Human DNAH9 PINC UniProtKB {GO:0005874=GO_REF:0000037, GO:0006928=PMID:8812413, GO:0007283=PMID:8703119, GO:0003777=GO_REF:0000029, GO:0035085=PMID:11104725, GO:0005524=GO_REF:0000037, GO:0003774=PMID:8812413, GO:0030286=GO_REF:0000002, GO:0030030=GO_REF:0000037, GO:0005858=GO_REF:0000029, GO:0005856=PMID:8812413, GO:0016887=GO_REF:0000002, GO:0007018=GO_REF:0000002} Q9NYC9 Dynein heavy chain 9, axonemal protein 20030904 {GO:0005874=IEA, GO:0006928=TAS, GO:0007283=TAS, GO:0003777=NAS, GO:0035085=IDA, GO:0005524=IEA, GO:0003774=TAS, GO:0030286=IEA, GO:0030030=IEA, GO:0005858=NAS, GO:0005856=TAS, GO:0016887=IEA, GO:0007018=IEA} cell projection organization, cellular component movement, microtubule-based movement, spermatogenesis axonemal dynein complex, cilium axoneme, cytoskeleton, dynein complex, microtubule ATP binding, ATPase activity, microtubule motor activity, motor activity Human DNAI1 PINC UniProtKB {GO:0005929=PMID:10577904, GO:0003774=GO_REF:0000037, GO:0003351=GO_REF:0000019, GO:0030286=GO_REF:0000037, GO:0030030=GO_REF:0000037, GO:0005874=GO_REF:0000037, GO:0005856=PMID:10577904, GO:0035085=GO_REF:0000039} Q9UI46 Dynein intermediate chain 1, axonemal protein 20030904 {GO:0005929=TAS, GO:0003774=IEA, GO:0003351=IEA, GO:0030286=IEA, GO:0030030=IEA, GO:0005874=IEA, GO:0005856=TAS, GO:0035085=IEA} cell projection organization, epithelial cilium movement cilium, cilium axoneme, cytoskeleton, dynein complex, microtubule motor activity Human DNAJA1 PINC UniProtKB {GO:0006986=PMID:8334160, GO:0016020=GO_REF:0000039, GO:0009408=GO_REF:0000002, GO:0006457=GO_REF:0000002, GO:0031072=GO_REF:0000002, GO:0030317=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0051082=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0030521=GO_REF:0000019, GO:0050750=PMID:15082773} P31689 DnaJ homolog subfamily A member 1 protein 20040806 {GO:0006986=TAS, GO:0016020=IEA, GO:0009408=IEA, GO:0006457=IEA, GO:0031072=IEA, GO:0030317=IEA, GO:0007283=IEA, GO:0051082=IEA, GO:0005524=IEA, GO:0046872=IEA, GO:0030521=IEA, GO:0050750=IDA} androgen receptor signaling pathway, protein folding, response to heat, response to unfolded protein, sperm motility, spermatogenesis membrane ATP binding, heat shock protein binding, low-density lipoprotein particle receptor binding, metal ion binding, unfolded protein binding Human DNAJA2 PINC UniProtKB {GO:0008284=PMID:9383053, GO:0016020=GO_REF:0000039, GO:0009408=GO_REF:0000002, GO:0006457=GO_REF:0000002, GO:0031072=GO_REF:0000002, GO:0051082=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0046872=GO_REF:0000037} O60884 DnaJ homolog subfamily A member 2 protein 20030904 {GO:0008284=TAS, GO:0016020=IEA, GO:0009408=IEA, GO:0006457=IEA, GO:0031072=IEA, GO:0051082=IEA, GO:0005524=IEA, GO:0046872=IEA} positive regulation of cell proliferation, protein folding, response to heat membrane ATP binding, heat shock protein binding, metal ion binding, unfolded protein binding Human DNAJA3 IntAct UniProtKB {GO:0005515=PMID:21106534, GO:0030054=GO_REF:0000037, GO:0008285=PMID:11719219, GO:0031594=GO_REF:0000024, GO:0009408=GO_REF:0000002, GO:0007264=GO_REF:0000019, GO:0005884=PMID:17588722, GO:0005634=GO_REF:0000019, GO:0009790=GO_REF:0000019, GO:0006924=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=GO_REF:0000039, GO:0005083=GO_REF:0000019, GO:0006457=GO_REF:0000002, GO:0045211=GO_REF:0000024, GO:0031072=GO_REF:0000002, GO:0005759=PMID:11719219, GO:0042102=GO_REF:0000019, GO:0030971=GO_REF:0000019, GO:0033077=GO_REF:0000019, GO:0007569=GO_REF:0000019, GO:0000122=PMID:21106534, GO:0005524=GO_REF:0000002, GO:0051082=GO_REF:0000019, GO:0006264=GO_REF:0000019, GO:0071340=GO_REF:0000024, GO:0019897=GO_REF:0000024} Q96EY1 DnaJ homolog subfamily A member 3, mitochondrial protein 20130415 {GO:0005515=IPI, GO:0030054=IEA, GO:0008285=IDA, GO:0031594=ISS, GO:0009408=IEA, GO:0007264=IEA, GO:0005884=IDA, GO:0005634=IEA, GO:0009790=IEA, GO:0006924=IEA, GO:0046872=IEA, GO:0005829=IEA, GO:0005083=IEA, GO:0006457=IEA, GO:0045211=ISS, GO:0031072=IEA, GO:0005759=IDA, GO:0042102=IEA, GO:0030971=IEA, GO:0033077=IEA, GO:0007569=IEA, GO:0000122=IDA, GO:0005524=IEA, GO:0051082=IEA, GO:0006264=IEA, GO:0071340=ISS, GO:0019897=ISS} T cell differentiation in thymus, activation-induced cell death of T cells, cell aging, embryo development, mitochondrial DNA replication, negative regulation of cell proliferation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of T cell proliferation, protein folding, response to heat, skeletal muscle acetylcholine-gated channel clustering, small GTPase mediated signal transduction actin filament, cell junction, cytosol, extrinsic to plasma membrane, mitochondrial matrix, neuromuscular junction, nucleus, postsynaptic membrane ATP binding, heat shock protein binding, metal ion binding, protein binding, receptor tyrosine kinase binding, small GTPase regulator activity, unfolded protein binding Human UniProtKB:P51692 DNAJA4 UniProtKB UniProtKB {GO:0016020=GO_REF:0000039, GO:0009408=GO_REF:0000002, GO:0006457=GO_REF:0000002, GO:0031072=GO_REF:0000002, GO:0051082=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q8WW22 DnaJ homolog subfamily A member 4 protein 20130413 {GO:0016020=IEA, GO:0009408=IEA, GO:0006457=IEA, GO:0031072=IEA, GO:0051082=IEA, GO:0005524=IEA, GO:0046872=IEA} protein folding, response to heat membrane ATP binding, heat shock protein binding, metal ion binding, unfolded protein binding Human UniProtKB-SubCell:SL-0162 DNAJB1 PINC UniProtKB {GO:0006986=PMID:8975727, GO:0005737=GO_REF:0000039, GO:0070389=PMID:18620420, GO:0006457=GO_REF:0000002, GO:0005730=GO_REF:0000039, GO:0051085=GO_REF:0000019, GO:0051082=GO_REF:0000002} P25685 DnaJ homolog subfamily B member 1 protein 20040806 {GO:0006986=TAS, GO:0005737=IEA, GO:0070389=IDA, GO:0006457=IEA, GO:0005730=IEA, GO:0051085=IEA, GO:0051082=IEA} chaperone cofactor-dependent protein refolding, chaperone mediated protein folding requiring cofactor, protein folding, response to unfolded protein cytoplasm, nucleolus unfolded protein binding Human DNAJB11 Reactome UniProtKB {GO:0005783=PMID:16130169, GO:0016556=GO_REF:0000019, GO:0006457=GO_REF:0000002, GO:0005788=Reactome:REACT_116120, GO:0005634=GO_REF:0000019, GO:0051082=GO_REF:0000019, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0030968=Reactome:REACT_18356} Q9UBS4 DnaJ homolog subfamily B member 11 protein 20130301 {GO:0005783=TAS, GO:0016556=IEA, GO:0006457=IEA, GO:0005788=TAS, GO:0005634=IEA, GO:0051082=IEA, GO:0006987=TAS, GO:0044267=TAS, GO:0030968=TAS} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, mRNA modification, protein folding endoplasmic reticulum, endoplasmic reticulum lumen, nucleus unfolded protein binding Human DNAJB12 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9NXW2 DnaJ homolog subfamily B member 12 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 DNAJB14 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8TBM8 DnaJ homolog subfamily B member 14 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 DNAJB2 PINC UniProtKB {GO:0006986=PMID:1599432, GO:0008219=GO_REF:0000037, GO:0030308=PMID:9553041, GO:0008285=PMID:9553041, GO:0006457=PMID:1599432, GO:0051082=PMID:1599432} P25686 DnaJ homolog subfamily B member 2 protein 20030904 {GO:0006986=TAS, GO:0008219=IEA, GO:0030308=IGI, GO:0008285=IGI, GO:0006457=TAS, GO:0051082=TAS} cell death, negative regulation of cell growth, negative regulation of cell proliferation, protein folding, response to unfolded protein unfolded protein binding Human DNAJB4 HPA UniProtKB {GO:0006986=PMID:9546042, GO:0005515=PMID:21255413, GO:0005737=GO_REF:0000052, GO:0009408=PMID:9546042, GO:0005886=GO_REF:0000052, GO:0006457=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0051082=GO_REF:0000002} Q9UDY4 DnaJ homolog subfamily B member 4 protein 20111111 {GO:0006986=TAS, GO:0005515=IPI, GO:0005737=IDA, GO:0009408=TAS, GO:0005886=IDA, GO:0006457=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0051082=IEA} protein folding, response to heat, response to unfolded protein cytoplasm, nucleolus, nucleus, plasma membrane protein binding, unfolded protein binding Human DNAJB5 ENSEMBL UniProtKB {GO:0005515=PMID:21078624, GO:0006986=PMID:10570961, GO:0006457=GO_REF:0000002, GO:0005634=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0051082=GO_REF:0000002, GO:0005829=GO_REF:0000019} Q5T657 DnaJ homolog subfamily B member 5 protein 20130413 {GO:0005515=IPI, GO:0006986=IEP, GO:0006457=IEA, GO:0005634=IEA, GO:0000122=IEA, GO:0051082=IEA, GO:0005829=IEA} negative regulation of transcription from RNA polymerase II promoter, protein folding, response to unfolded protein cytosol, nucleus protein binding, unfolded protein binding Human Ensembl:ENSMUSP00000081712 DNAJB6 GOC UniProtKB {GO:0005515=PMID:16919237, GO:0006986=GO_REF:0000029, GO:0030018=PMID:22366786, GO:0048471=PMID:10954706, GO:0045109=PMID:10954706, GO:0005730=GO_REF:0000052, GO:0051087=PMID:11896048, GO:0005634=GO_REF:0000052, GO:0032781=PMID:11896048, GO:0005737=GO_REF:0000052, GO:0006457=PMID:11896048, GO:0031072=PMID:10954706, GO:0043154=PMID:11896048, GO:0001671=PMID:11896048} O75190 DnaJ homolog subfamily B member 6 protein 20130413 {GO:0005515=IPI, GO:0006986=NAS, GO:0030018=IDA, GO:0048471=IDA, GO:0045109=IDA, GO:0005730=IDA, GO:0051087=IDA, GO:0005634=IDA, GO:0032781=IDA, GO:0005737=IDA, GO:0006457=IDA, GO:0031072=IDA, GO:0043154=IDA, GO:0001671=IDA} intermediate filament organization, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of ATPase activity, protein folding, response to unfolded protein Z disc, cytoplasm, nucleolus, nucleus, perinuclear region of cytoplasm ATPase activator activity, chaperone binding, heat shock protein binding, protein binding Human DNAJB8 null null {} null null null null {} null null null DNAJB9 Reactome UniProtKB {GO:0051787=PMID:18400946, GO:0005515=PMID:19815549, GO:0005737=GO_REF:0000024, GO:0005783=GO_REF:0000054, GO:0005789=Reactome:REACT_115866, GO:0005730=GO_REF:0000024, GO:0006987=Reactome:REACT_18368, GO:0030433=PMID:18400946, GO:0044267=Reactome:REACT_17015, GO:0030968=Reactome:REACT_18356} Q9UBS3 DnaJ homolog subfamily B member 9 protein 20130301 {GO:0051787=IDA, GO:0005515=IPI, GO:0005737=ISS, GO:0005783=IDA, GO:0005789=TAS, GO:0005730=ISS, GO:0006987=TAS, GO:0030433=IMP, GO:0044267=TAS, GO:0030968=TAS} ER-associated protein catabolic process, activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response cytoplasm, endoplasmic reticulum, endoplasmic reticulum membrane, nucleolus misfolded protein binding, protein binding Human DNAJC1 HPA UniProtKB {GO:0005515=PMID:14668352, GO:0031965=GO_REF:0000039, GO:0005783=GO_REF:0000052, GO:0051087=GO_REF:0000019, GO:0032781=PMID:14668352, GO:0003677=GO_REF:0000037, GO:0006417=GO_REF:0000019, GO:0045861=PMID:14668352, GO:0006457=GO_REF:0000019, GO:0003682=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0050708=PMID:14668352, GO:0016021=GO_REF:0000037, GO:0001671=PMID:14668352} Q96KC8 DnaJ homolog subfamily C member 1 protein 20081203 {GO:0005515=IPI, GO:0031965=IEA, GO:0005783=IDA, GO:0051087=IEA, GO:0032781=TAS, GO:0003677=IEA, GO:0006417=IEA, GO:0045861=TAS, GO:0006457=IEA, GO:0003682=IEA, GO:0005789=IEA, GO:0050708=IDA, GO:0016021=IEA, GO:0001671=TAS} negative regulation of proteolysis, positive regulation of ATPase activity, protein folding, regulation of protein secretion, regulation of translation endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, nuclear membrane ATPase activator activity, DNA binding, chaperone binding, chromatin binding, protein binding Human DNAJC10 UniProtKB UniProtKB {GO:0005515=PMID:19815549, GO:0034976=PMID:19122239, GO:0005783=PMID:12411443, GO:0006662=GO_REF:0000002, GO:0051087=PMID:12411443, GO:0015035=GO_REF:0000002, GO:0015036=GO_REF:0000024, GO:0009055=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0032781=GO_REF:0000024, GO:0030433=PMID:18400946, GO:0051787=PMID:18400946, GO:0070059=PMID:19122239, GO:0034663=PMID:18400946, GO:0005788=GO_REF:0000039, GO:0001933=PMID:19122239, GO:0051117=PMID:12411443, GO:0045454=GO_REF:0000002, GO:0001671=GO_REF:0000024} Q8IXB1 DnaJ homolog subfamily C member 10 protein 20100203 {GO:0005515=IPI, GO:0034976=IDA, GO:0005783=IDA, GO:0006662=IEA, GO:0051087=IDA, GO:0015035=IEA, GO:0015036=ISS, GO:0009055=IEA, GO:0005576=IEA, GO:0032781=ISS, GO:0030433=IMP, GO:0051787=IDA, GO:0070059=IDA, GO:0034663=IDA, GO:0005788=IEA, GO:0001933=IDA, GO:0051117=IPI, GO:0045454=IEA, GO:0001671=ISS} ER-associated protein catabolic process, cell redox homeostasis, glycerol ether metabolic process, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, negative regulation of protein phosphorylation, positive regulation of ATPase activity, response to endoplasmic reticulum stress endoplasmic reticulum, endoplasmic reticulum chaperone complex, endoplasmic reticulum lumen, extracellular region ATPase activator activity, ATPase binding, chaperone binding, disulfide oxidoreductase activity, electron carrier activity, misfolded protein binding, protein binding, protein disulfide oxidoreductase activity Human UniProtKB:Q5HYA8 DNAJC11 ENSEMBL UniProtKB {GO:0005743=GO_REF:0000019} Q9NVH1 DnaJ homolog subfamily C member 11 protein 20130413 {GO:0005743=IEA} mitochondrial inner membrane Human Ensembl:ENSMUSP00000051643 DNAJC12 null null {} null null null null {} null null null DNAJC13 null null {} null null null null {} null null null DNAJC14 HPA UniProtKB {GO:0005730=GO_REF:0000052, GO:0005789=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0016021=GO_REF:0000037, GO:0015031=GO_REF:0000037} Q6Y2X3 DnaJ homolog subfamily C member 14 protein 20120912 {GO:0005730=IDA, GO:0005789=IEA, GO:0005634=IDA, GO:0016021=IEA, GO:0015031=IEA} protein transport endoplasmic reticulum membrane, integral to membrane, nucleolus, nucleus NOT Human DNAJC15 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q9Y5T4 DnaJ homolog subfamily C member 15 protein 20130413 {GO:0005739=IEA, GO:0016021=IEA} integral to membrane, mitochondrion Human Ensembl:ENSMUSP00000022590 DNAJC16 UniProtKB UniProtKB {GO:0045454=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q9Y2G8 DnaJ homolog subfamily C member 16 protein 20130413 {GO:0045454=IEA, GO:0016021=IEA} cell redox homeostasis integral to membrane Human UniProtKB-KW:KW-0812 DNAJC17 UniProtKB UniProtKB {GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037} Q9NVM6 DnaJ homolog subfamily C member 17 protein 20130413 {GO:0000166=IEA, GO:0003723=IEA} RNA binding, nucleotide binding Human UniProtKB-KW:KW-0694 DNAJC19 Reactome UniProtKB {GO:0005739=PMID:12592411, GO:0006457=PMID:16055927, GO:0006626=Reactome:REACT_118595, GO:0005743=GO_REF:0000039, GO:0048806=PMID:16055927, GO:0016021=PMID:16055927, GO:0044267=Reactome:REACT_17015, GO:0007601=PMID:16055927} Q96DA6 Mitochondrial import inner membrane translocase subunit TIM14 protein 20110427 {GO:0005739=IDA, GO:0006457=NAS, GO:0006626=TAS, GO:0005743=IEA, GO:0048806=IMP, GO:0016021=NAS, GO:0044267=TAS, GO:0007601=IMP} cellular protein metabolic process, genitalia development, protein folding, protein targeting to mitochondrion, visual perception integral to membrane, mitochondrial inner membrane, mitochondrion Human DNAJC2 HPA UniProtKB {GO:0043130=PMID:21179169, GO:0031965=GO_REF:0000052, GO:0030308=GO_REF:0000019, GO:0005634=PMID:21179169, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0005829=PMID:16002468, GO:0006260=GO_REF:0000019, GO:0000085=GO_REF:0000019, GO:0042393=PMID:21179169, GO:0005737=GO_REF:0000052, GO:0003682=PMID:21179169, GO:0030544=PMID:16002468, GO:0051083=PMID:16002468, GO:0045893=PMID:21179169, GO:0016568=GO_REF:0000037} Q99543 DnaJ homolog subfamily C member 2 protein 20100326 {GO:0043130=IDA, GO:0031965=IDA, GO:0030308=IEA, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA, GO:0005829=IDA, GO:0006260=IEA, GO:0000085=IEA, GO:0042393=IDA, GO:0005737=IDA, GO:0003682=IDA, GO:0030544=IPI, GO:0051083=TAS, GO:0045893=IDA, GO:0016568=IEA} 'de novo' cotranslational protein folding, DNA replication, G2 phase of mitotic cell cycle, chromatin modification, negative regulation of cell growth, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, cytosol, nuclear membrane, nucleus DNA binding, Hsp70 protein binding, chromatin binding, histone binding, ubiquitin binding Human DNAJC21 IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0003674=GO_REF:0000015, GO:0006457=PMID:16952052, GO:0005840=PMID:16952052, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q5F1R6 DnaJ homolog subfamily C member 21 protein 20130415 {GO:0005515=IPI, GO:0003674=ND, GO:0006457=NAS, GO:0005840=NAS, GO:0008270=IEA, GO:0003676=IEA} protein folding ribosome molecular_function, nucleic acid binding, protein binding, zinc ion binding Human UniProtKB:Q99551 DNAJC22 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8N4W6 DnaJ homolog subfamily C member 22 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 DNAJC28 null null {} null null null null {} null null null DNAJC3 GOC UniProtKB {GO:0051787=GO_REF:0000019, GO:0005737=PMID:8666242, GO:0051607=GO_REF:0000037, GO:0051603=GO_REF:0000019, GO:0051087=GO_REF:0000019, GO:0005788=Reactome:REACT_115787, GO:0004860=PMID:7511204, GO:0006469=PMID:7511204, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0031205=GO_REF:0000019, GO:0030968=Reactome:REACT_18356} Q13217 DnaJ homolog subfamily C member 3 protein 20130413 {GO:0051787=IEA, GO:0005737=TAS, GO:0051607=IEA, GO:0051603=IEA, GO:0051087=IEA, GO:0005788=TAS, GO:0004860=TAS, GO:0006469=TAS, GO:0006987=TAS, GO:0044267=TAS, GO:0031205=IEA, GO:0030968=TAS} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, defense response to virus, endoplasmic reticulum unfolded protein response, negative regulation of protein kinase activity, proteolysis involved in cellular protein catabolic process cytoplasm, endoplasmic reticulum Sec complex, endoplasmic reticulum lumen chaperone binding, misfolded protein binding, protein kinase inhibitor activity Human DNAJC30 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019} Q96LL9 DnaJ homolog subfamily C member 30 protein 20130413 {GO:0005739=IEA} mitochondrion Human Ensembl:ENSMUSP00000094318 DNAJC4 PINC UniProtKB {GO:0006986=PMID:9473517, GO:0005739=GO_REF:0000019, GO:0016020=PMID:9473517, GO:0006457=PMID:9473517, GO:0051082=PMID:9473517, GO:0016021=GO_REF:0000037} Q9NNZ3 DnaJ homolog subfamily C member 4 protein 20050308 {GO:0006986=TAS, GO:0005739=IEA, GO:0016020=NAS, GO:0006457=NAS, GO:0051082=NAS, GO:0016021=IEA} protein folding, response to unfolded protein integral to membrane, membrane, mitochondrion unfolded protein binding Human DNAJC5 Reactome UniProtKB {GO:0042470=GO_REF:0000039, GO:0008219=GO_REF:0000037, GO:0043524=GO_REF:0000019, GO:0043008=GO_REF:0000019, GO:0001948=GO_REF:0000019, GO:0005886=Reactome:REACT_23813, GO:0007268=Reactome:REACT_13685, GO:0061202=Reactome:REACT_23973, GO:0007269=Reactome:REACT_13723, GO:0008021=GO_REF:0000019} Q9H3Z4 DnaJ homolog subfamily C member 5 protein 20120214 {GO:0042470=IEA, GO:0008219=IEA, GO:0043524=IEA, GO:0043008=IEA, GO:0001948=IEA, GO:0005886=TAS, GO:0007268=TAS, GO:0061202=TAS, GO:0007269=TAS, GO:0008021=IEA} cell death, negative regulation of neuron apoptotic process, neurotransmitter secretion, synaptic transmission clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane, melanosome, plasma membrane, synaptic vesicle ATP-dependent protein binding, glycoprotein binding Human DNAJC5B UniProtKB UniProtKB {GO:0016020=GO_REF:0000039} Q9UF47 DnaJ homolog subfamily C member 5B protein 20130413 {GO:0016020=IEA} membrane Human UniProtKB-SubCell:SL-0162 DNAJC6 Reactome UniProtKB {GO:0017124=GO_REF:0000037, GO:0006892=Reactome:REACT_11235, GO:0016044=Reactome:REACT_11123, GO:0004725=GO_REF:0000003, GO:0005829=Reactome:REACT_19206} O75061 Putative tyrosine-protein phosphatase auxilin protein 20130213 {GO:0017124=IEA, GO:0006892=TAS, GO:0016044=TAS, GO:0004725=IEA, GO:0005829=TAS} cellular membrane organization, post-Golgi vesicle-mediated transport cytosol SH3 domain binding, protein tyrosine phosphatase activity Human DNAJC7 HPA UniProtKB {GO:0005515=PMID:22190034, GO:0005737=GO_REF:0000052, GO:0006457=PMID:8836031, GO:0070389=PMID:18620420, GO:0031072=PMID:12853476, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005856=GO_REF:0000039} Q99615 DnaJ homolog subfamily C member 7 protein 20100326 {GO:0005515=IPI, GO:0005737=IDA, GO:0006457=TAS, GO:0070389=IDA, GO:0031072=IPI, GO:0005730=IDA, GO:0005634=IDA, GO:0005856=IEA} chaperone cofactor-dependent protein refolding, protein folding cytoplasm, cytoskeleton, nucleolus, nucleus heat shock protein binding, protein binding Human DNAJC8 Reactome UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0000398=Reactome:REACT_467, GO:0005654=Reactome:REACT_1935} O75937 DnaJ homolog subfamily C member 8 protein 20130213 {GO:0008380=TAS, GO:0010467=TAS, GO:0000398=TAS, GO:0005654=TAS} RNA splicing, gene expression, mRNA splicing, via spliceosome nucleoplasm Human DNAJC9 UniProtKB UniProtKB {GO:0035176=PMID:21531385} Q8WXX5 DnaJ homolog subfamily C member 9 protein 20111216 {GO:0035176=IEP} social behavior Human DNAL4 Reactome UniProtKB {GO:0048011=Reactome:REACT_11061, GO:0005886=Reactome:REACT_12385, GO:0042623=GO_REF:0000029, GO:0005875=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0005858=GO_REF:0000029, GO:0003777=GO_REF:0000029, GO:0035085=GO_REF:0000039, GO:0007017=GO_REF:0000002, GO:0007018=GO_REF:0000029} O96015 Dynein light chain 4, axonemal protein 20130301 {GO:0048011=TAS, GO:0005886=TAS, GO:0042623=NAS, GO:0005875=IEA, GO:0005874=IEA, GO:0005858=NAS, GO:0003777=NAS, GO:0035085=IEA, GO:0007017=IEA, GO:0007018=NAS} microtubule-based movement, microtubule-based process, neurotrophin TRK receptor signaling pathway axonemal dynein complex, cilium axoneme, microtubule, microtubule associated complex, plasma membrane ATPase activity, coupled, microtubule motor activity Human DNALI1 BHF-UCL UniProtKB {GO:0007338=PMID:9284741, GO:0005737=PMID:19944400, GO:0005930=PMID:9284741, GO:0006928=PMID:9284741, GO:0005858=PMID:9284741, GO:0003777=PMID:9284741} O14645 Axonemal dynein light intermediate polypeptide 1 protein 20120423 {GO:0007338=TAS, GO:0005737=IDA, GO:0005930=TAS, GO:0006928=TAS, GO:0005858=TAS, GO:0003777=TAS} cellular component movement, single fertilization axonemal dynein complex, axoneme, cytoplasm microtubule motor activity Human DNASE1 UniProtKB UniProtKB {GO:0005515=PMID:12849983, GO:0004536=GO_REF:0000002, GO:0006308=GO_REF:0000002, GO:0006915=GO_REF:0000037, GO:0005576=GO_REF:0000039, GO:0003779=GO_REF:0000037, GO:0005635=GO_REF:0000039, GO:0004530=GO_REF:0000003, GO:0016888=GO_REF:0000002} P24855 Deoxyribonuclease-1 protein 20051104 {GO:0005515=IPI, GO:0004536=IEA, GO:0006308=IEA, GO:0006915=IEA, GO:0005576=IEA, GO:0003779=IEA, GO:0005635=IEA, GO:0004530=IEA, GO:0016888=IEA} DNA catabolic process, apoptotic process extracellular region, nuclear envelope actin binding, deoxyribonuclease I activity, deoxyribonuclease activity, endodeoxyribonuclease activity, producing 5'-phosphomonoesters, protein binding Human UniProtKB:P68133 DNASE1L2 PINC UniProtKB {GO:0004536=PMID:9205125, GO:0006308=GO_REF:0000002, GO:0005509=PMID:9205125, GO:0005576=GO_REF:0000039, GO:0006259=PMID:9205125, GO:0016888=GO_REF:0000002, GO:0003677=PMID:9205125} Q92874 Deoxyribonuclease-1-like 2 protein 20030904 {GO:0004536=TAS, GO:0006308=IEA, GO:0005509=TAS, GO:0005576=IEA, GO:0006259=TAS, GO:0016888=IEA, GO:0003677=TAS} DNA catabolic process, DNA metabolic process extracellular region DNA binding, calcium ion binding, deoxyribonuclease activity, endodeoxyribonuclease activity, producing 5'-phosphomonoesters Human DNASE2 PINC UniProtKB {GO:0006308=GO_REF:0000019, GO:0030218=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0004531=GO_REF:0000003, GO:0006259=PMID:9714827, GO:0003677=PMID:9714827, GO:0005764=GO_REF:0000039} O00115 Deoxyribonuclease-2-alpha protein 20030904 {GO:0006308=IEA, GO:0030218=IEA, GO:0006915=IEA, GO:0004531=IEA, GO:0006259=TAS, GO:0003677=TAS, GO:0005764=IEA} DNA catabolic process, DNA metabolic process, apoptotic process, erythrocyte differentiation lysosome DNA binding, deoxyribonuclease II activity Human DNASE2B UniProtKB UniProtKB {GO:0005576=GO_REF:0000019, GO:0004531=GO_REF:0000003, GO:0006259=GO_REF:0000002, GO:0005764=GO_REF:0000039} Q8WZ79 Deoxyribonuclease-2-beta protein 20130413 {GO:0005576=IEA, GO:0004531=IEA, GO:0006259=IEA, GO:0005764=IEA} DNA metabolic process extracellular region, lysosome deoxyribonuclease II activity Human UniProtKB-SubCell:SL-0158 DNER Reactome UniProtKB {GO:0005515=PMID:11950833, GO:0007220=GO_REF:0000019, GO:0005886=PMID:11950833, GO:0005509=PMID:11950833, GO:0005112=GO_REF:0000019, GO:0048741=GO_REF:0000019, GO:0007417=PMID:11950833, GO:0007416=PMID:11950833, GO:0030425=PMID:11950833, GO:0006897=PMID:11950833, GO:0007219=Reactome:REACT_118859, GO:0030276=PMID:11950833, GO:0043025=GO_REF:0000019, GO:0010001=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0001764=PMID:11950833, GO:0005769=PMID:11950833, GO:0004888=PMID:11950833} Q8NFT8 Delta and Notch-like epidermal growth factor-related receptor protein 20110917 {GO:0005515=IPI, GO:0007220=IEA, GO:0005886=IDA, GO:0005509=NAS, GO:0005112=IEA, GO:0048741=IEA, GO:0007417=IEP, GO:0007416=NAS, GO:0030425=IDA, GO:0006897=NAS, GO:0007219=TAS, GO:0030276=TAS, GO:0043025=IEA, GO:0010001=IEA, GO:0016021=IEA, GO:0001764=NAS, GO:0005769=IDA, GO:0004888=TAS} Notch receptor processing, Notch signaling pathway, central nervous system development, endocytosis, glial cell differentiation, neuron migration, skeletal muscle fiber development, synapse assembly dendrite, early endosome, integral to membrane, neuronal cell body, plasma membrane Notch binding, calcium ion binding, clathrin binding, protein binding, transmembrane signaling receptor activity Human DNHD1 InterPro UniProtKB {GO:0030286=GO_REF:0000002, GO:0003777=GO_REF:0000002, GO:0007018=GO_REF:0000002} Q96M86 Dynein heavy chain domain-containing protein 1 protein 20130413 {GO:0030286=IEA, GO:0003777=IEA, GO:0007018=IEA} microtubule-based movement dynein complex microtubule motor activity Human InterPro:IPR004273 DNLZ ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0008270=GO_REF:0000002} Q5SXM8 DNL-type zinc finger protein protein 20130413 {GO:0005739=IEA, GO:0008270=IEA} mitochondrion zinc ion binding Human Ensembl:ENSMUSP00000028295 DNM1 GOC UniProtKB {GO:0005515=PMID:21706016, GO:0005874=GO_REF:0000037, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0008022=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0030117=GO_REF:0000019, GO:0006898=PMID:10521508, GO:0042802=PMID:21962517, GO:0006897=PMID:19706678, GO:0006184=PMID:10944110, GO:0031623=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0007032=PMID:19706678} Q05193 Dynamin-1 protein 20130413 {GO:0005515=IPI, GO:0005874=IEA, GO:0003924=IEA, GO:0005525=IEA, GO:0008022=IEA, GO:0032403=IEA, GO:0030117=IEA, GO:0006898=IMP, GO:0042802=IPI, GO:0006897=IMP, GO:0006184=TAS, GO:0031623=IEA, GO:0005543=IEA, GO:0007032=IMP} GTP catabolic process, endocytosis, endosome organization, receptor internalization, receptor-mediated endocytosis membrane coat, microtubule GTP binding, GTPase activity, identical protein binding, phospholipid binding, protein C-terminus binding, protein binding, protein complex binding Human DNM1L BHF-UCL UniProtKB {GO:0005515=PMID:21217774, GO:0003374=PMID:11514614, GO:0048471=PMID:9570752, GO:0090149=PMID:11514614, GO:1900063=PMID:18353969, GO:0050714=PMID:9570752, GO:0003924=GO_REF:0000002, GO:0005741=Reactome:REACT_13560, GO:0090141=PMID:20436456, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_13560, GO:0005737=PMID:21149567, GO:0051289=PMID:18353969, GO:0090200=PMID:21149567, GO:0031625=PMID:19407830, GO:0016559=PMID:12618434, GO:0005777=PMID:12618434, GO:0005794=PMID:20688057, GO:0010821=PMID:21149567, GO:0006915=Reactome:REACT_578, GO:2001244=PMID:20850011, GO:0005525=GO_REF:0000037, GO:0043653=PMID:12499352, GO:0012505=GO_REF:0000039, GO:0043234=PMID:17408615, GO:0070584=PMID:21149567} O00429 Dynamin-1-like protein protein 20110404 {GO:0005515=IPI, GO:0003374=IDA, GO:0048471=IDA, GO:0090149=IDA, GO:1900063=IMP, GO:0050714=IDA, GO:0003924=IEA, GO:0005741=TAS, GO:0090141=TAS, GO:0006921=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0051289=IDA, GO:0090200=IMP, GO:0031625=IPI, GO:0016559=IDA, GO:0005777=IDA, GO:0005794=IDA, GO:0010821=IMP, GO:0006915=TAS, GO:2001244=IMP, GO:0005525=IEA, GO:0043653=IMP, GO:0012505=IEA, GO:0043234=IDA, GO:0070584=IMP} apoptotic process, cellular component disassembly involved in execution phase of apoptosis, dynamin polymerization involved in mitochondrial fission, membrane fission involved in mitochondrial fission, mitochondrial fragmentation involved in apoptotic process, mitochondrion morphogenesis, peroxisome fission, positive regulation of intrinsic apoptotic signaling pathway, positive regulation of mitochondrial fission, positive regulation of protein secretion, positive regulation of release of cytochrome c from mitochondria, protein homotetramerization, regulation of mitochondrion organization, regulation of peroxisome organization Golgi apparatus, cytoplasm, cytosol, endomembrane system, mitochondrial outer membrane, perinuclear region of cytoplasm, peroxisome, protein complex GTP binding, GTPase activity, protein binding, ubiquitin protein ligase binding Human DNM2 GOC UniProtKB {GO:0005515=PMID:22623184, GO:0008017=PMID:7590285, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_12634, GO:0050999=Reactome:REACT_12541, GO:0003924=Reactome:REACT_19255, GO:0005634=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0032403=GO_REF:0000019, GO:0005829=Reactome:REACT_121003, GO:0031623=PMID:14985334, GO:0033572=PMID:14985334, GO:0019886=Reactome:REACT_121399, GO:0005737=GO_REF:0000029, GO:0005543=GO_REF:0000002, GO:0045211=PMID:11583995, GO:0000086=PMID:7590285, GO:0046209=Reactome:REACT_12508, GO:0006355=PMID:10893263, GO:0043065=PMID:10893263, GO:0019901=GO_REF:0000019, GO:0005874=PMID:21525035, GO:0006892=Reactome:REACT_11235, GO:0030496=GO_REF:0000039, GO:0014069=GO_REF:0000039, GO:0048489=PMID:11583995, GO:0005525=PMID:7590285, GO:0006898=GO_REF:0000019, GO:0006897=PMID:10101292, GO:0006184=Reactome:REACT_19255, GO:0030666=Reactome:REACT_12634, GO:0007165=PMID:10893263, GO:0045334=GO_REF:0000019, GO:0000139=Reactome:REACT_19334, GO:0019899=PMID:11583995, GO:0045893=PMID:10893263, GO:0016044=Reactome:REACT_11123} P50570 Dynamin-2 protein 20130413 {GO:0005515=IPI, GO:0008017=NAS, GO:0030054=IEA, GO:0005886=TAS, GO:0050999=TAS, GO:0003924=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0032403=IEA, GO:0005829=TAS, GO:0031623=IMP, GO:0033572=IMP, GO:0019886=TAS, GO:0005737=NAS, GO:0005543=IEA, GO:0045211=IDA, GO:0000086=NAS, GO:0046209=TAS, GO:0006355=NAS, GO:0043065=NAS, GO:0019901=IEA, GO:0005874=IDA, GO:0006892=TAS, GO:0030496=IEA, GO:0014069=IEA, GO:0048489=NAS, GO:0005525=NAS, GO:0006898=IEA, GO:0006897=NAS, GO:0006184=TAS, GO:0030666=TAS, GO:0007165=NAS, GO:0045334=IEA, GO:0000139=TAS, GO:0019899=NAS, GO:0045893=NAS, GO:0016044=TAS} G2/M transition of mitotic cell cycle, GTP catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class II, cellular membrane organization, endocytosis, nitric oxide metabolic process, positive regulation of apoptotic process, positive regulation of transcription, DNA-dependent, post-Golgi vesicle-mediated transport, receptor internalization, receptor-mediated endocytosis, regulation of nitric-oxide synthase activity, regulation of transcription, DNA-dependent, signal transduction, small molecule metabolic process, synaptic vesicle transport, transferrin transport Golgi membrane, cell junction, clathrin-coated endocytic vesicle, cytoplasm, cytosol, endocytic vesicle membrane, microtubule, midbody, nucleus, plasma membrane, postsynaptic density, postsynaptic membrane GTP binding, GTPase activity, enzyme binding, microtubule binding, phospholipid binding, protein binding, protein complex binding, protein kinase binding Human DNM3 GOC UniProtKB {GO:0005515=PMID:15252009, GO:0048471=GO_REF:0000024, GO:0005874=GO_REF:0000037, GO:0003924=GO_REF:0000024, GO:0014069=GO_REF:0000024, GO:0005525=GO_REF:0000037, GO:0007416=GO_REF:0000024, GO:0006897=GO_REF:0000024, GO:0005739=GO_REF:0000019, GO:0006184=GO_REF:0000024, GO:0005543=GO_REF:0000002, GO:0043197=GO_REF:0000024, GO:0046847=GO_REF:0000024} Q9UQ16 Dynamin-3 protein 20130413 {GO:0005515=IPI, GO:0048471=ISS, GO:0005874=IEA, GO:0003924=ISS, GO:0014069=ISS, GO:0005525=IEA, GO:0007416=ISS, GO:0006897=ISS, GO:0005739=IEA, GO:0006184=ISS, GO:0005543=IEA, GO:0043197=ISS, GO:0046847=ISS} GTP catabolic process, endocytosis, filopodium assembly, synapse assembly dendritic spine, microtubule, mitochondrion, perinuclear region of cytoplasm, postsynaptic density GTP binding, GTPase activity, phospholipid binding, protein binding Human UniProtKB:Q08877 DNMBP IntAct UniProtKB {GO:0005515=PMID:18654987, GO:0005622=GO_REF:0000002, GO:0035556=GO_REF:0000002, GO:0005737=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005795=GO_REF:0000039, GO:0035023=GO_REF:0000002, GO:0045202=GO_REF:0000039, GO:0005856=GO_REF:0000039, GO:0005089=GO_REF:0000002} Q6XZF7 Dynamin-binding protein protein 20130415 {GO:0005515=IPI, GO:0005622=IEA, GO:0035556=IEA, GO:0005737=IEA, GO:0030054=IEA, GO:0005795=IEA, GO:0035023=IEA, GO:0045202=IEA, GO:0005856=IEA, GO:0005089=IEA} intracellular signal transduction, regulation of Rho protein signal transduction Golgi stack, cell junction, cytoplasm, cytoskeleton, intracellular, synapse Rho guanyl-nucleotide exchange factor activity, protein binding Human UniProtKB:Q9NQY0 DNMT1 IntAct UniProtKB {GO:0005515=PMID:22094255, GO:0008327=GO_REF:0000019, GO:0003886=PMID:21745816, GO:0003723=GO_REF:0000019, GO:0005657=GO_REF:0000019, GO:0008168=GO_REF:0000002, GO:0016458=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0000122=PMID:10888872, GO:0003677=PMID:18754681, GO:0006351=GO_REF:0000037, GO:0010628=PMID:18413740, GO:0006306=PMID:10888872, GO:0010216=PMID:21745816, GO:0005721=GO_REF:0000019, GO:0051571=PMID:18413740, GO:0071230=GO_REF:0000019, GO:0009008=PMID:18754681, GO:0051573=PMID:18413740, GO:0042127=GO_REF:0000019, GO:0008270=GO_REF:0000019, GO:0008134=GO_REF:0000002, GO:0016568=GO_REF:0000037} P26358 DNA (cytosine-5)-methyltransferase 1 protein 20130415 {GO:0005515=IPI, GO:0008327=IEA, GO:0003886=IDA, GO:0003723=IEA, GO:0005657=IEA, GO:0008168=IEA, GO:0016458=IEA, GO:0005634=IEA, GO:0000122=TAS, GO:0003677=IDA, GO:0006351=IEA, GO:0010628=IMP, GO:0006306=TAS, GO:0010216=IDA, GO:0005721=IEA, GO:0051571=IMP, GO:0071230=IEA, GO:0009008=IDA, GO:0051573=IMP, GO:0042127=IEA, GO:0008270=IEA, GO:0008134=IEA, GO:0016568=IEA} DNA methylation, cellular response to amino acid stimulus, chromatin modification, gene silencing, maintenance of DNA methylation, negative regulation of histone H3-K9 methylation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of gene expression, positive regulation of histone H3-K4 methylation, regulation of cell proliferation, transcription, DNA-dependent centromeric heterochromatin, nucleus, replication fork DNA (cytosine-5-)-methyltransferase activity, DNA binding, DNA-methyltransferase activity, RNA binding, methyl-CpG binding, methyltransferase activity, protein binding, transcription factor binding, zinc ion binding Human UniProtKB:O75530 DNMT3A HPA UniProtKB {GO:0005515=PMID:16357870, GO:0000791=PMID:12138111, GO:0003886=PMID:12138111, GO:0006346=GO_REF:0000019, GO:0008168=GO_REF:0000002, GO:0010424=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0007283=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0044027=GO_REF:0000019, GO:0016363=PMID:12138111, GO:0045322=GO_REF:0000019, GO:0005737=PMID:12138111, GO:0071230=GO_REF:0000019, GO:0051718=GO_REF:0000019, GO:0043045=GO_REF:0000019, GO:0043046=GO_REF:0000019, GO:0090116=PMID:12138111, GO:0005730=GO_REF:0000052, GO:0000122=GO_REF:0000019, GO:0003677=PMID:12138111, GO:0006306=PMID:12138111, GO:0005720=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0006349=PMID:12138111, GO:0046498=GO_REF:0000019, GO:0000775=GO_REF:0000019, GO:0046499=GO_REF:0000019} Q9Y6K1 DNA (cytosine-5)-methyltransferase 3A protein 20111111 {GO:0005515=IPI, GO:0000791=IDA, GO:0003886=IDA, GO:0006346=IEA, GO:0008168=IEA, GO:0010424=IEA, GO:0005634=IDA, GO:0007283=IEA, GO:0046872=IEA, GO:0044027=IEA, GO:0016363=IDA, GO:0045322=IEA, GO:0005737=IDA, GO:0071230=IEA, GO:0051718=IEA, GO:0043045=IEA, GO:0043046=IEA, GO:0090116=IDA, GO:0005730=IDA, GO:0000122=IEA, GO:0003677=IDA, GO:0006306=IDA, GO:0005720=IEA, GO:0003682=IEA, GO:0006349=TAS, GO:0046498=IEA, GO:0000775=IEA, GO:0046499=IEA} C-5 methylation of cytosine, DNA methylation, DNA methylation involved in embryo development, DNA methylation involved in gamete generation, DNA methylation on cytosine within a CG sequence, S-adenosylhomocysteine metabolic process, S-adenosylmethioninamine metabolic process, cellular response to amino acid stimulus, hypermethylation of CpG island, methylation-dependent chromatin silencing, negative regulation of transcription from RNA polymerase II promoter, regulation of gene expression by genetic imprinting, spermatogenesis chromosome, centromeric region, cytoplasm, euchromatin, nuclear heterochromatin, nuclear matrix, nucleolus, nucleus DNA (cytosine-5-)-methyltransferase activity, DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates, DNA binding, chromatin binding, metal ion binding, methyltransferase activity, protein binding, unmethylated CpG binding NOT Human DNMT3B HPA UniProtKB {GO:0005515=PMID:11735126, GO:0003886=PMID:16543361, GO:0003714=PMID:17303076, GO:0006346=GO_REF:0000019, GO:0031503=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000122=PMID:17303076, GO:0003677=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0006306=PMID:10555141, GO:0010628=PMID:18413740, GO:0005720=GO_REF:0000019, GO:0071230=GO_REF:0000019, GO:0051571=PMID:18413740, GO:0009008=PMID:11102980, GO:0051573=PMID:18413740, GO:0006349=GO_REF:0000019} Q9UBC3 DNA (cytosine-5)-methyltransferase 3B protein 20101115 {GO:0005515=IPI, GO:0003886=IDA, GO:0003714=IDA, GO:0006346=IEA, GO:0031503=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0000122=IDA, GO:0003677=IEA, GO:0046872=IEA, GO:0043231=IDA, GO:0006306=NAS, GO:0010628=IMP, GO:0005720=IEA, GO:0071230=IEA, GO:0051571=IMP, GO:0009008=NAS, GO:0051573=IMP, GO:0006349=IEA} DNA methylation, cellular response to amino acid stimulus, methylation-dependent chromatin silencing, negative regulation of histone H3-K9 methylation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of gene expression, positive regulation of histone H3-K4 methylation, protein complex localization, regulation of gene expression by genetic imprinting intracellular membrane-bounded organelle, nuclear heterochromatin, nucleolus, nucleus DNA (cytosine-5-)-methyltransferase activity, DNA binding, DNA-methyltransferase activity, metal ion binding, protein binding, transcription corepressor activity Human DNMT3L GOC UniProtKB {GO:0005515=PMID:12202768, GO:0000794=GO_REF:0000019, GO:0005634=PMID:16780588, GO:0001890=GO_REF:0000019, GO:0007283=PMID:11934864, GO:0043085=PMID:16543361, GO:0001701=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=PMID:16780588, GO:0006306=PMID:12202768, GO:0005720=GO_REF:0000019, GO:0006349=PMID:12202768, GO:0060718=GO_REF:0000019, GO:0008047=PMID:16543361, GO:0019899=PMID:12202768, GO:0045892=PMID:12202768} Q9UJW3 DNA (cytosine-5)-methyltransferase 3-like protein 20130413 {GO:0005515=IPI, GO:0000794=IEA, GO:0005634=IDA, GO:0001890=IEA, GO:0007283=NAS, GO:0043085=IDA, GO:0001701=IEA, GO:0046872=IEA, GO:0005829=IDA, GO:0006306=NAS, GO:0005720=IEA, GO:0006349=NAS, GO:0060718=IEA, GO:0008047=IDA, GO:0019899=IPI, GO:0045892=IDA} DNA methylation, chorionic trophoblast cell differentiation, in utero embryonic development, negative regulation of transcription, DNA-dependent, placenta development, positive regulation of catalytic activity, regulation of gene expression by genetic imprinting, spermatogenesis condensed nuclear chromosome, cytosol, nuclear heterochromatin, nucleus enzyme activator activity, enzyme binding, metal ion binding, protein binding Human DNPEP PINC UniProtKB {GO:0005737=GO_REF:0000039, GO:0004177=GO_REF:0000037, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0008237=GO_REF:0000037, GO:0006518=PMID:9632644} Q9ULA0 Aspartyl aminopeptidase protein 20030904 {GO:0005737=IEA, GO:0004177=IEA, GO:0006508=IEA, GO:0008270=IEA, GO:0008237=IEA, GO:0006518=TAS} peptide metabolic process, proteolysis cytoplasm aminopeptidase activity, metallopeptidase activity, zinc ion binding Human DNTT HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0003887=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003912=GO_REF:0000003, GO:0006304=GO_REF:0000037, GO:0003677=GO_REF:0000002, GO:0046872=GO_REF:0000037} P04053 DNA nucleotidylexotransferase protein 20110516 {GO:0005737=IDA, GO:0003887=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003912=IEA, GO:0006304=IEA, GO:0003677=IEA, GO:0046872=IEA} DNA modification cytoplasm, nucleolus, nucleus DNA binding, DNA nucleotidylexotransferase activity, DNA-directed DNA polymerase activity, metal ion binding Human DNTTIP1 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039} Q9H147 Deoxynucleotidyltransferase terminal-interacting protein 1 protein 20130413 {GO:0005634=IEA} nucleus Human UniProtKB-SubCell:SL-0191 DNTTIP2 HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037} Q5QJE6 Deoxynucleotidyltransferase terminal-interacting protein 2 protein 20111111 {GO:0006355=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus, nucleus Human DOC2A PINC UniProtKB {GO:0005515=PMID:18354201, GO:0005215=GO_REF:0000002, GO:0043005=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0007268=PMID:7826360, GO:0005764=GO_REF:0000039, GO:0016079=GO_REF:0000019, GO:0008021=GO_REF:0000002, GO:0007399=PMID:7826360, GO:0005544=GO_REF:0000037, GO:0017158=PMID:18354201, GO:0016020=GO_REF:0000002, GO:0030672=GO_REF:0000039} Q14183 Double C2-like domain-containing protein alpha protein 20030904 {GO:0005515=IPI, GO:0005215=IEA, GO:0043005=IEA, GO:0030054=IEA, GO:0007268=TAS, GO:0005764=IEA, GO:0016079=IEA, GO:0008021=IEA, GO:0007399=TAS, GO:0005544=IEA, GO:0017158=IMP, GO:0016020=IEA, GO:0030672=IEA} nervous system development, regulation of calcium ion-dependent exocytosis, synaptic transmission, synaptic vesicle exocytosis cell junction, lysosome, membrane, neuron projection, synaptic vesicle, synaptic vesicle membrane calcium-dependent phospholipid binding, protein binding, transporter activity Human DOC2B HPA UniProtKB {GO:0019905=GO_REF:0000019, GO:0005215=GO_REF:0000002, GO:0005886=GO_REF:0000024, GO:0048791=GO_REF:0000024, GO:0031340=GO_REF:0000024, GO:0031201=GO_REF:0000024, GO:0008021=GO_REF:0000002, GO:0005544=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0008104=GO_REF:0000024, GO:0045956=GO_REF:0000024, GO:0015630=GO_REF:0000052, GO:0032024=GO_REF:0000024} Q14184 Double C2-like domain-containing protein beta protein 20120912 {GO:0019905=IEA, GO:0005215=IEA, GO:0005886=ISS, GO:0048791=ISS, GO:0031340=ISS, GO:0031201=ISS, GO:0008021=IEA, GO:0005544=ISS, GO:0005737=ISS, GO:0008104=ISS, GO:0045956=ISS, GO:0015630=IDA, GO:0032024=ISS} calcium ion-dependent exocytosis of neurotransmitter, positive regulation of calcium ion-dependent exocytosis, positive regulation of insulin secretion, positive regulation of vesicle fusion, protein localization SNARE complex, cytoplasm, microtubule cytoskeleton, plasma membrane, synaptic vesicle calcium-dependent phospholipid binding, syntaxin binding, transporter activity Human DOCK1 GOC UniProtKB {GO:0005515=PMID:20936779, GO:0017124=GO_REF:0000037, GO:0007264=GO_REF:0000002, GO:0006915=GO_REF:0000037, GO:0006911=PMID:9548255, GO:0005829=Reactome:REACT_160134, GO:0043547=PMID:9808620, GO:0005085=GO_REF:0000037, GO:0007165=PMID:8661160, GO:0005737=PMID:8661160, GO:0016477=GO_REF:0000019, GO:0016020=GO_REF:0000039, GO:0007596=Reactome:REACT_604, GO:0007229=PMID:9808620, GO:0007411=Reactome:REACT_18266, GO:0045087=Reactome:REACT_6802, GO:0038096=Reactome:REACT_160123, GO:0005096=PMID:9808620} Q14185 Dedicator of cytokinesis protein 1 protein 20130413 {GO:0005515=IPI, GO:0017124=IEA, GO:0007264=IEA, GO:0006915=IEA, GO:0006911=TAS, GO:0005829=TAS, GO:0043547=TAS, GO:0005085=IEA, GO:0007165=TAS, GO:0005737=TAS, GO:0016477=IEA, GO:0016020=IEA, GO:0007596=TAS, GO:0007229=TAS, GO:0007411=TAS, GO:0045087=TAS, GO:0038096=TAS, GO:0005096=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, apoptotic process, axon guidance, blood coagulation, cell migration, innate immune response, integrin-mediated signaling pathway, phagocytosis, engulfment, positive regulation of GTPase activity, signal transduction, small GTPase mediated signal transduction cytoplasm, cytosol, membrane GTPase activator activity, SH3 domain binding, guanyl-nucleotide exchange factor activity, protein binding Human DOCK10 ENSEMBL UniProtKB {GO:0005085=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0017048=GO_REF:0000019, GO:0005089=GO_REF:0000019} Q96BY6 Dedicator of cytokinesis protein 10 protein 20130413 {GO:0005085=IEA, GO:0005543=IEA, GO:0007264=IEA, GO:0017048=IEA, GO:0005089=IEA} small GTPase mediated signal transduction Rho GTPase binding, Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, phospholipid binding Human Ensembl:ENSMUSP00000077099 DOCK11 Reactome UniProtKB {GO:0005085=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0007264=GO_REF:0000002, GO:0017048=GO_REF:0000019, GO:0005089=GO_REF:0000019, GO:0005829=Reactome:REACT_25140} Q5JSL3 Dedicator of cytokinesis protein 11 protein 20130301 {GO:0005085=IEA, GO:0005543=IEA, GO:0007596=TAS, GO:0007264=IEA, GO:0017048=IEA, GO:0005089=IEA, GO:0005829=TAS} blood coagulation, small GTPase mediated signal transduction cytosol Rho GTPase binding, Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, phospholipid binding Human DOCK2 Reactome UniProtKB {GO:0030036=PMID:12176041, GO:0007264=GO_REF:0000002, GO:0046633=GO_REF:0000019, GO:0005829=Reactome:REACT_11090, GO:0005085=GO_REF:0000002, GO:0050766=GO_REF:0000024, GO:0042608=PMID:12176041, GO:0006935=GO_REF:0000019, GO:0007010=GO_REF:0000019, GO:0016032=Reactome:REACT_6185, GO:0005856=GO_REF:0000039, GO:0030675=GO_REF:0000019, GO:0030676=PMID:10559471, GO:0001771=GO_REF:0000019, GO:0009055=GO_REF:0000002, GO:0045059=GO_REF:0000019, GO:0012505=GO_REF:0000039, GO:0050690=Reactome:REACT_11068, GO:0044351=GO_REF:0000024, GO:0016020=GO_REF:0000037, GO:0001768=GO_REF:0000019, GO:0045060=GO_REF:0000019, GO:0002277=GO_REF:0000024, GO:0001766=GO_REF:0000019, GO:0020037=GO_REF:0000002} Q92608 Dedicator of cytokinesis protein 2 protein 20130213 {GO:0030036=TAS, GO:0007264=IEA, GO:0046633=IEA, GO:0005829=TAS, GO:0005085=IEA, GO:0050766=ISS, GO:0042608=IDA, GO:0006935=IEA, GO:0007010=IEA, GO:0016032=TAS, GO:0005856=IEA, GO:0030675=IEA, GO:0030676=IDA, GO:0001771=IEA, GO:0009055=IEA, GO:0045059=IEA, GO:0012505=IEA, GO:0050690=TAS, GO:0044351=ISS, GO:0016020=IEA, GO:0001768=IEA, GO:0045060=IEA, GO:0002277=ISS, GO:0001766=IEA, GO:0020037=IEA} actin cytoskeleton organization, alpha-beta T cell proliferation, chemotaxis, cytoskeleton organization, establishment of T cell polarity, immunological synapse formation, macropinocytosis, membrane raft polarization, myeloid dendritic cell activation involved in immune response, negative thymic T cell selection, positive regulation of phagocytosis, positive thymic T cell selection, regulation of defense response to virus by virus, small GTPase mediated signal transduction, viral reproduction cytoskeleton, cytosol, endomembrane system, membrane Rac GTPase activator activity, Rac guanyl-nucleotide exchange factor activity, T cell receptor binding, electron carrier activity, guanyl-nucleotide exchange factor activity, heme binding Human DOCK3 HPA UniProtKB {GO:0005515=PMID:17474147, GO:0005085=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0017124=GO_REF:0000037, GO:0007264=GO_REF:0000002} Q8IZD9 Dedicator of cytokinesis protein 3 protein 20110516 {GO:0005515=IPI, GO:0005085=IEA, GO:0005737=IDA, GO:0017124=IEA, GO:0007264=IEA} small GTPase mediated signal transduction cytoplasm SH3 domain binding, guanyl-nucleotide exchange factor activity, protein binding Human DOCK4 GOC UniProtKB {GO:0005515=PMID:16464467, GO:0030971=PMID:20679435, GO:0017124=GO_REF:0000037, GO:0007264=GO_REF:0000002, GO:0032420=PMID:16464467, GO:0032421=PMID:16464467, GO:0030165=PMID:16464467, GO:0032855=PMID:16464467, GO:0012505=GO_REF:0000039, GO:0005829=PMID:20679435, GO:0005085=GO_REF:0000037, GO:0048365=PMID:16464467, GO:0016020=PMID:20679435, GO:0060326=PMID:20679435, GO:0030675=PMID:16464467} Q8N1I0 Dedicator of cytokinesis protein 4 protein 20130413 {GO:0005515=IPI, GO:0030971=IPI, GO:0017124=IEA, GO:0007264=IEA, GO:0032420=ISS, GO:0032421=ISS, GO:0030165=IPI, GO:0032855=IDA, GO:0012505=IEA, GO:0005829=IDA, GO:0005085=IEA, GO:0048365=IDA, GO:0016020=IDA, GO:0060326=IMP, GO:0030675=IDA} cell chemotaxis, positive regulation of Rac GTPase activity, small GTPase mediated signal transduction cytosol, endomembrane system, membrane, stereocilium, stereocilium bundle PDZ domain binding, Rac GTPase activator activity, Rac GTPase binding, SH3 domain binding, guanyl-nucleotide exchange factor activity, protein binding, receptor tyrosine kinase binding Human DOCK5 HPA UniProtKB {GO:0005085=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0007264=GO_REF:0000002} Q9H7D0 Dedicator of cytokinesis protein 5 protein 20090616 {GO:0005085=ISS, GO:0005737=IDA, GO:0007264=IEA} small GTPase mediated signal transduction cytoplasm guanyl-nucleotide exchange factor activity Human DOCK6 Reactome UniProtKB {GO:0005085=GO_REF:0000037, GO:0048471=GO_REF:0000039, GO:0007596=Reactome:REACT_604, GO:0007264=GO_REF:0000002, GO:0005829=Reactome:REACT_25140} Q96HP0 Dedicator of cytokinesis protein 6 protein 20130301 {GO:0005085=IEA, GO:0048471=IEA, GO:0007596=TAS, GO:0007264=IEA, GO:0005829=TAS} blood coagulation, small GTPase mediated signal transduction cytosol, perinuclear region of cytoplasm guanyl-nucleotide exchange factor activity Human DOCK7 BHF-UCL UniProtKB {GO:0030424=PMID:16982419, GO:0043005=PMID:16982419, GO:0007264=GO_REF:0000002, GO:0045178=PMID:16982419, GO:0000226=PMID:16982419, GO:0045200=PMID:16982419, GO:0007409=PMID:16982419, GO:0032863=PMID:16982419, GO:0031175=PMID:16982419, GO:0030426=PMID:16982419, GO:0005085=GO_REF:0000037, GO:0048365=PMID:16982419, GO:0033138=PMID:16982419, GO:0008180=PMID:18850735, GO:0043473=GO_REF:0000019} Q96N67 Dedicator of cytokinesis protein 7 protein 20080204 {GO:0030424=TAS, GO:0043005=TAS, GO:0007264=IEA, GO:0045178=TAS, GO:0000226=IMP, GO:0045200=IMP, GO:0007409=IMP, GO:0032863=IDA, GO:0031175=IMP, GO:0030426=TAS, GO:0005085=IEA, GO:0048365=IDA, GO:0033138=IMP, GO:0008180=IDA, GO:0043473=IEA} activation of Rac GTPase activity, axonogenesis, establishment of neuroblast polarity, microtubule cytoskeleton organization, neuron projection development, pigmentation, positive regulation of peptidyl-serine phosphorylation, small GTPase mediated signal transduction axon, basal part of cell, growth cone, neuron projection, signalosome Rac GTPase binding, guanyl-nucleotide exchange factor activity Human DOCK8 Reactome UniProtKB {GO:0005085=GO_REF:0000037, GO:0007596=Reactome:REACT_604, GO:0007264=GO_REF:0000002, GO:0005829=Reactome:REACT_25140} Q8NF50 Dedicator of cytokinesis protein 8 protein 20130301 {GO:0005085=IEA, GO:0007596=TAS, GO:0007264=IEA, GO:0005829=TAS} blood coagulation, small GTPase mediated signal transduction cytosol guanyl-nucleotide exchange factor activity Human DOCK9 IntAct UniProtKB {GO:0005515=PMID:18729074, GO:0005085=GO_REF:0000002, GO:0008150=GO_REF:0000015, GO:0005543=GO_REF:0000002, GO:0016020=GO_REF:0000037, GO:0007596=Reactome:REACT_604, GO:0007264=GO_REF:0000002, GO:0017048=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0005089=GO_REF:0000019, GO:0005829=Reactome:REACT_25140, GO:0012505=GO_REF:0000039} Q9BZ29 Dedicator of cytokinesis protein 9 protein 20130415 {GO:0005515=IPI, GO:0005085=IEA, GO:0008150=ND, GO:0005543=IEA, GO:0016020=IEA, GO:0007596=TAS, GO:0007264=IEA, GO:0017048=IEA, GO:0005575=ND, GO:0005089=IEA, GO:0005829=TAS, GO:0012505=IEA} biological_process, blood coagulation, small GTPase mediated signal transduction cellular_component, cytosol, endomembrane system, membrane Rho GTPase binding, Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, phospholipid binding, protein binding Human UniProtKB:Q15796 DOHH Reactome UniProtKB {GO:0005515=PMID:17213197, GO:0008612=Reactome:REACT_12469, GO:0005575=GO_REF:0000015, GO:0019135=Reactome:REACT_12479, GO:0044267=Reactome:REACT_17015, GO:0046872=GO_REF:0000037, GO:0043687=Reactome:REACT_22161, GO:0005829=Reactome:REACT_12479} Q9BU89 Deoxyhypusine hydroxylase protein 20071128 {GO:0005515=IPI, GO:0008612=TAS, GO:0005575=ND, GO:0019135=TAS, GO:0044267=TAS, GO:0046872=IEA, GO:0043687=TAS, GO:0005829=TAS} cellular protein metabolic process, peptidyl-lysine modification to hypusine, post-translational protein modification cellular_component, cytosol deoxyhypusine monooxygenase activity, metal ion binding, protein binding Human DOK1 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0008286=Reactome:REACT_498, GO:0007165=PMID:9008160, GO:0048471=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0005158=GO_REF:0000002, GO:0007265=GO_REF:0000019, GO:0005057=GO_REF:0000019, GO:0007169=PMID:9008160, GO:0007166=PMID:10799545, GO:0007243=GO_REF:0000019, GO:0005829=Reactome:REACT_2120} Q99704 Docking protein 1 protein 20130415 {GO:0005515=IPI, GO:0008286=TAS, GO:0007165=TAS, GO:0048471=IEA, GO:0005543=IEA, GO:0005158=IEA, GO:0007265=IEA, GO:0005057=IEA, GO:0007169=TAS, GO:0007166=TAS, GO:0007243=IEA, GO:0005829=TAS} Ras protein signal transduction, cell surface receptor signaling pathway, insulin receptor signaling pathway, intracellular protein kinase cascade, signal transduction, transmembrane receptor protein tyrosine kinase signaling pathway cytosol, perinuclear region of cytoplasm insulin receptor binding, phospholipid binding, protein binding, receptor signaling protein activity Human UniProtKB:Q9Q2G4 DOK2 Reactome UniProtKB {GO:0007165=PMID:9478921, GO:0005543=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0005158=GO_REF:0000002, GO:0005068=GO_REF:0000019, GO:0007265=GO_REF:0000019, GO:0005057=GO_REF:0000019, GO:0050900=Reactome:REACT_12051, GO:0007166=PMID:10799545, GO:0005829=Reactome:REACT_12575} O60496 Docking protein 2 protein 20071203 {GO:0007165=TAS, GO:0005543=IEA, GO:0007596=TAS, GO:0005158=IEA, GO:0005068=IEA, GO:0007265=IEA, GO:0005057=IEA, GO:0050900=TAS, GO:0007166=TAS, GO:0005829=TAS} Ras protein signal transduction, blood coagulation, cell surface receptor signaling pathway, leukocyte migration, signal transduction cytosol insulin receptor binding, phospholipid binding, receptor signaling protein activity, transmembrane receptor protein tyrosine kinase adaptor activity Human DOK3 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0005158=GO_REF:0000002, GO:0007265=GO_REF:0000019} Q7L591 Docking protein 3 protein 20130413 {GO:0005737=IEA, GO:0005543=IEA, GO:0005886=IEA, GO:0005158=IEA, GO:0007265=IEA} Ras protein signal transduction cytoplasm, plasma membrane insulin receptor binding, phospholipid binding Human UniProtKB-SubCell:SL-0039 DOK4 ENSEMBL UniProtKB {GO:0005543=GO_REF:0000002, GO:0000165=GO_REF:0000019, GO:0005158=GO_REF:0000002, GO:0005057=GO_REF:0000019, GO:0007169=GO_REF:0000019, GO:0007399=GO_REF:0000019} Q8TEW6 Docking protein 4 protein 20130413 {GO:0005543=IEA, GO:0000165=IEA, GO:0005158=IEA, GO:0005057=IEA, GO:0007169=IEA, GO:0007399=IEA} MAPK cascade, nervous system development, transmembrane receptor protein tyrosine kinase signaling pathway insulin receptor binding, phospholipid binding, receptor signaling protein activity Human Ensembl:ENSMUSP00000043554 DOK5 ENSEMBL UniProtKB {GO:0005543=GO_REF:0000002, GO:0000165=GO_REF:0000019, GO:0005158=GO_REF:0000002, GO:0005057=GO_REF:0000019, GO:0007169=GO_REF:0000019, GO:0007399=GO_REF:0000019} Q9P104 Docking protein 5 protein 20130413 {GO:0005543=IEA, GO:0000165=IEA, GO:0005158=IEA, GO:0005057=IEA, GO:0007169=IEA, GO:0007399=IEA} MAPK cascade, nervous system development, transmembrane receptor protein tyrosine kinase signaling pathway insulin receptor binding, phospholipid binding, receptor signaling protein activity Human Ensembl:ENSMUSP00000029075 DOK6 InterPro UniProtKB {GO:0005543=GO_REF:0000002, GO:0005158=GO_REF:0000002} Q6PKX4 Docking protein 6 protein 20130413 {GO:0005543=IEA, GO:0005158=IEA} insulin receptor binding, phospholipid binding Human InterPro:IPR001849 DOK7 UniProtKB UniProtKB {GO:0031594=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005543=GO_REF:0000002, GO:0019901=PMID:20603078, GO:0005886=GO_REF:0000039, GO:0007528=GO_REF:0000019, GO:0061098=PMID:20603078, GO:0005158=GO_REF:0000002, GO:0043113=GO_REF:0000019, GO:0035091=GO_REF:0000019} Q18PE1 Protein Dok-7 protein 20110610 {GO:0031594=IEA, GO:0030054=IEA, GO:0005543=IEA, GO:0019901=IDA, GO:0005886=IEA, GO:0007528=IEA, GO:0061098=IDA, GO:0005158=IEA, GO:0043113=IEA, GO:0035091=IEA} neuromuscular junction development, positive regulation of protein tyrosine kinase activity, receptor clustering cell junction, neuromuscular junction, plasma membrane insulin receptor binding, phosphatidylinositol binding, phospholipid binding, protein kinase binding Human DOLK Reactome UniProtKB {GO:0004168=PMID:12213788, GO:0005789=Reactome:REACT_22276, GO:0030176=PMID:16923818, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0006489=Reactome:REACT_22230, GO:0043048=PMID:12213788, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q9UPQ8 Dolichol kinase protein 20130301 {GO:0004168=IDA, GO:0005789=TAS, GO:0030176=IDA, GO:0006488=TAS, GO:0044267=TAS, GO:0006489=TAS, GO:0043048=IDA, GO:0043687=TAS, GO:0018279=TAS} cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, dolichyl diphosphate biosynthetic process, dolichyl monophosphate biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane dolichol kinase activity Human DOLPP1 Reactome UniProtKB {GO:0005789=Reactome:REACT_22114, GO:0030176=GO_REF:0000024, GO:0006487=GO_REF:0000024, GO:0047874=GO_REF:0000024, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0006489=Reactome:REACT_22230, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q86YN1 Dolichyldiphosphatase 1 protein 20130301 {GO:0005789=TAS, GO:0030176=ISS, GO:0006487=ISS, GO:0047874=ISS, GO:0006488=TAS, GO:0044267=TAS, GO:0006489=TAS, GO:0043687=TAS, GO:0018279=TAS} cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, dolichyl diphosphate biosynthetic process, post-translational protein modification, protein N-linked glycosylation, protein N-linked glycosylation via asparagine endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane dolichyldiphosphatase activity Human DOM3Z UniProtKB UniProtKB {GO:0000166=GO_REF:0000037, GO:0046872=GO_REF:0000037} O77932 Protein Dom3Z protein 20130413 {GO:0000166=IEA, GO:0046872=IEA} metal ion binding, nucleotide binding Human UniProtKB-KW:KW-0479 DONSON UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0005575=GO_REF:0000015} Q9NYP3 Protein downstream neighbor of Son protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0005634=IEA, GO:0007275=IEA, GO:0005575=ND} biological_process, multicellular organismal development cellular_component, nucleus molecular_function Human DOPEY1 HGNC UniProtKB {GO:0000139=PMID:16301316, GO:0015031=GO_REF:0000037, GO:0007029=PMID:16301316, GO:0006895=PMID:16301316} Q5TA12 Protein dopey-1 protein 20060201 {GO:0000139=ISS, GO:0015031=IEA, GO:0007029=ISS, GO:0006895=ISS} Golgi to endosome transport, endoplasmic reticulum organization, protein transport Golgi membrane Human UniProtKB:Q03921 DOPEY2 HGNC UniProtKB {GO:0003674=GO_REF:0000015, GO:0000139=PMID:16301316, GO:0007275=PMID:10950924, GO:0015031=GO_REF:0000037, GO:0007029=PMID:16301316, GO:0006895=PMID:16301316} Q9Y3R5 Protein dopey-2 protein 20060201 {GO:0003674=ND, GO:0000139=ISS, GO:0007275=NAS, GO:0015031=IEA, GO:0007029=ISS, GO:0006895=ISS} Golgi to endosome transport, endoplasmic reticulum organization, multicellular organismal development, protein transport Golgi membrane molecular_function Human UniProtKB:Q03921 DOT1L GOC UniProtKB {GO:0005515=PMID:20153263, GO:0034968=PMID:17707234, GO:0046425=PMID:22002246, GO:0005634=GO_REF:0000039, GO:2000677=PMID:22002246, GO:0003677=GO_REF:0000037, GO:0018024=PMID:17707234} Q8TEK3 Histone-lysine N-methyltransferase, H3 lysine-79 specific protein 20130413 {GO:0005515=IPI, GO:0034968=IDA, GO:0046425=IDA, GO:0005634=IEA, GO:2000677=IMP, GO:0003677=IEA, GO:0018024=IDA} histone lysine methylation, regulation of JAK-STAT cascade, regulation of transcription regulatory region DNA binding nucleus DNA binding, histone-lysine N-methyltransferase activity, protein binding Human DPAGT1 Reactome UniProtKB {GO:0016757=GO_REF:0000037, GO:0019408=PMID:8179616, GO:0030176=PMID:12872255, GO:0006047=GO_REF:0000019, GO:0051259=GO_REF:0000024, GO:0043231=PMID:12872255, GO:0016020=PMID:8179616, GO:0003975=PMID:12872255, GO:0005789=Reactome:REACT_22147, GO:0016021=GO_REF:0000024, GO:0006487=PMID:19549906, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426, GO:0008963=GO_REF:0000002} Q9H3H5 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase protein 20130301 {GO:0016757=IEA, GO:0019408=IDA, GO:0030176=NAS, GO:0006047=IEA, GO:0051259=ISS, GO:0043231=IDA, GO:0016020=IDA, GO:0003975=IMP, GO:0005789=TAS, GO:0016021=ISS, GO:0006487=IMP, GO:0006488=TAS, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS, GO:0008963=IEA} UDP-N-acetylglucosamine metabolic process, cellular protein metabolic process, dolichol biosynthetic process, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation, protein N-linked glycosylation via asparagine, protein oligomerization endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle, membrane UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity, phospho-N-acetylmuramoyl-pentapeptide-transferase activity, transferase activity, transferring glycosyl groups Human DPCD ENSEMBL UniProtKB {GO:0007368=GO_REF:0000019, GO:0021670=GO_REF:0000019, GO:0003351=GO_REF:0000019, GO:0060972=GO_REF:0000019, GO:0030317=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0021678=GO_REF:0000019} Q9BVM2 Protein DPCD protein 20130413 {GO:0007368=IEA, GO:0021670=IEA, GO:0003351=IEA, GO:0060972=IEA, GO:0030317=IEA, GO:0007283=IEA, GO:0021678=IEA} determination of left/right symmetry, epithelial cilium movement, lateral ventricle development, left/right pattern formation, sperm motility, spermatogenesis, third ventricle development Human Ensembl:ENSMUSP00000045683 DPCR1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q3MIW9 Diffuse panbronchiolitis critical region protein 1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 DPEP1 IntAct UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0005515=PMID:16189514, GO:0034235=GO_REF:0000024, GO:0071732=GO_REF:0000024, GO:0005886=Reactome:REACT_15395, GO:0031528=GO_REF:0000039, GO:0006749=PMID:20031578, GO:0031225=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0005615=GO_REF:0000024, GO:0006691=Reactome:REACT_150420, GO:0050667=PMID:20031578, GO:0072341=PMID:20031578, GO:0072340=PMID:12144777, GO:0016324=GO_REF:0000039, GO:0070573=PMID:19879002, GO:0006508=GO_REF:0000037, GO:0071277=GO_REF:0000024, GO:0030336=PMID:20824289, GO:0045177=PMID:20824289, GO:0016805=GO_REF:0000002, GO:0016999=PMID:8737157, GO:0008235=PMID:2303490, GO:0008270=PMID:19879002, GO:0008239=GO_REF:0000002} P16444 Dipeptidase 1 protein 20130415 {GO:0019369=TAS, GO:0005515=IPI, GO:0034235=ISS, GO:0071732=ISS, GO:0005886=TAS, GO:0031528=IEA, GO:0006749=TAS, GO:0031225=IEA, GO:0044281=TAS, GO:0005615=ISS, GO:0006691=TAS, GO:0050667=IDA, GO:0072341=IDA, GO:0072340=TAS, GO:0016324=IEA, GO:0070573=IDA, GO:0006508=IEA, GO:0071277=ISS, GO:0030336=IMP, GO:0045177=IDA, GO:0016805=IEA, GO:0016999=IDA, GO:0008235=TAS, GO:0008270=IDA, GO:0008239=IEA} antibiotic metabolic process, arachidonic acid metabolic process, cellular lactam catabolic process, cellular response to calcium ion, cellular response to nitric oxide, glutathione metabolic process, homocysteine metabolic process, leukotriene metabolic process, negative regulation of cell migration, proteolysis, small molecule metabolic process anchored to membrane, apical part of cell, apical plasma membrane, extracellular space, microvillus membrane, plasma membrane GPI anchor binding, dipeptidase activity, dipeptidyl-peptidase activity, metallodipeptidase activity, metalloexopeptidase activity, modified amino acid binding, protein binding, zinc ion binding Human UniProtKB:Q96EK5 DPEP2 Reactome UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0005886=Reactome:REACT_15395, GO:0008235=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0031225=GO_REF:0000037, GO:0008239=GO_REF:0000002, GO:0006691=Reactome:REACT_150420, GO:0016805=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q9H4A9 Dipeptidase 2 protein 20130301 {GO:0019369=TAS, GO:0005886=TAS, GO:0008235=IEA, GO:0006508=IEA, GO:0044281=TAS, GO:0031225=IEA, GO:0008239=IEA, GO:0006691=TAS, GO:0016805=IEA, GO:0046872=IEA} arachidonic acid metabolic process, leukotriene metabolic process, proteolysis, small molecule metabolic process anchored to membrane, plasma membrane dipeptidase activity, dipeptidyl-peptidase activity, metal ion binding, metalloexopeptidase activity Human DPEP3 UniProtKB UniProtKB {GO:0006508=GO_REF:0000019, GO:0008235=GO_REF:0000002, GO:0031225=GO_REF:0000037, GO:0008239=GO_REF:0000002, GO:0016805=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0007140=GO_REF:0000024} Q9H4B8 Dipeptidase 3 protein 20120815 {GO:0006508=IEA, GO:0008235=IEA, GO:0031225=IEA, GO:0008239=IEA, GO:0016805=IEA, GO:0046872=IEA, GO:0007140=ISS} male meiosis, proteolysis anchored to membrane dipeptidase activity, dipeptidyl-peptidase activity, metal ion binding, metalloexopeptidase activity Human UniProtKB:Q9DA79 DPF1 PINC UniProtKB {GO:0005737=GO_REF:0000039, GO:0006355=GO_REF:0000037, GO:0071565=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0006917=PMID:8812431, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0007399=GO_REF:0000024} Q92782 Zinc finger protein neuro-d4 protein 20030904 {GO:0005737=IEA, GO:0006355=IEA, GO:0071565=ISS, GO:0008270=IEA, GO:0006917=TAS, GO:0003676=IEA, GO:0006351=IEA, GO:0007399=ISS} induction of apoptosis, nervous system development, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nBAF complex nucleic acid binding, zinc ion binding Human DPF2 HPA UniProtKB {GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0006917=PMID:8812431, GO:0097190=PMID:7961935, GO:0006351=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q92785 Zinc finger protein ubi-d4 protein 20101115 {GO:0005813=IDA, GO:0005737=IDA, GO:0006355=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0006917=TAS, GO:0097190=TAS, GO:0006351=IEA, GO:0043231=IDA} apoptotic signaling pathway, induction of apoptosis, regulation of transcription, DNA-dependent, transcription, DNA-dependent centrosome, cytoplasm, intracellular membrane-bounded organelle, nucleolus, nucleus zinc ion binding Human DPF3 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0071565=GO_REF:0000024, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000029, GO:0008270=PMID:8812431, GO:0006351=GO_REF:0000037, GO:0007399=GO_REF:0000019, GO:0016568=GO_REF:0000037} Q92784 Zinc finger protein DPF3 protein 20100126 {GO:0008150=ND, GO:0071565=ISS, GO:0006355=IEA, GO:0005634=NAS, GO:0008270=NAS, GO:0006351=IEA, GO:0007399=IEA, GO:0016568=IEA} biological_process, chromatin modification, nervous system development, regulation of transcription, DNA-dependent, transcription, DNA-dependent nBAF complex, nucleus zinc ion binding Human UniProtKB:P58269 DPH1 PINC UniProtKB {GO:0005737=GO_REF:0000039, GO:0008283=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0006412=PMID:8603384, GO:0017183=GO_REF:0000002} Q9BZG8 Diphthamide biosynthesis protein 1 protein 20030904 {GO:0005737=IEA, GO:0008283=IEA, GO:0005634=IEA, GO:0006412=TAS, GO:0017183=IEA} cell proliferation, peptidyl-diphthamide biosynthetic process from peptidyl-histidine, translation cytoplasm, nucleus Human DPH2 InterPro UniProtKB {GO:0005737=GO_REF:0000002, GO:0017183=GO_REF:0000002} Q9BQC3 Diphthamide biosynthesis protein 2 protein 20130413 {GO:0005737=IEA, GO:0017183=IEA} peptidyl-diphthamide biosynthetic process from peptidyl-histidine cytoplasm Human InterPro:IPR002728|InterPro:IPR010014 DPH3 HPA UniProtKB {GO:0005515=PMID:14980502, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0050709=PMID:14980502, GO:0051099=PMID:14980502, GO:0005634=GO_REF:0000052, GO:0017183=GO_REF:0000024, GO:0046872=GO_REF:0000037} Q96FX2 DPH3 homolog protein 20101115 {GO:0005515=IPI, GO:0005737=IDA, GO:0005730=IDA, GO:0050709=IDA, GO:0051099=IDA, GO:0005634=IDA, GO:0017183=ISS, GO:0046872=IEA} negative regulation of protein secretion, peptidyl-diphthamide biosynthetic process from peptidyl-histidine, positive regulation of binding cytoplasm, nucleolus, nucleus metal ion binding, protein binding Human DPH5 UniProtKB UniProtKB {GO:0004164=PMID:15485916, GO:0008168=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0017183=PMID:15485916} Q9H2P9 Diphthine synthase protein 20081106 {GO:0004164=NAS, GO:0008168=IEA, GO:0005575=ND, GO:0017183=NAS} peptidyl-diphthamide biosynthetic process from peptidyl-histidine cellular_component diphthine synthase activity, methyltransferase activity Human DPM1 HGNC UniProtKB {GO:0006501=Reactome:REACT_1853, GO:0005515=PMID:10835346, GO:0004582=PMID:9535917, GO:0033185=PMID:9724629, GO:0016757=GO_REF:0000038, GO:0043178=GO_REF:0000019, GO:0005783=PMID:9724629, GO:0019348=PMID:9724629, GO:0019673=GO_REF:0000019, GO:0005537=GO_REF:0000019, GO:0035269=PMID:9535917, GO:0035268=PMID:9535917, GO:0004169=PMID:9535917, GO:0016020=PMID:9535917, GO:0005789=Reactome:REACT_2036, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0006506=PMID:9535917, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} O60762 Dolichol-phosphate mannosyltransferase protein 20070403 {GO:0006501=TAS, GO:0005515=IPI, GO:0004582=IDA, GO:0033185=IDA, GO:0016757=IEA, GO:0043178=IEA, GO:0005783=IDA, GO:0019348=IDA, GO:0019673=IEA, GO:0005537=IEA, GO:0035269=IDA, GO:0035268=IDA, GO:0004169=IDA, GO:0016020=IDA, GO:0005789=TAS, GO:0006488=TAS, GO:0044267=TAS, GO:0006506=IDA, GO:0043687=TAS, GO:0018279=TAS} C-terminal protein lipidation, GDP-mannose metabolic process, GPI anchor biosynthetic process, cellular protein metabolic process, dolichol metabolic process, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine, protein O-linked mannosylation, protein mannosylation dolichol-phosphate-mannose synthase complex, endoplasmic reticulum, endoplasmic reticulum membrane, membrane alcohol binding, dolichyl-phosphate beta-D-mannosyltransferase activity, dolichyl-phosphate-mannose-protein mannosyltransferase activity, mannose binding, protein binding, transferase activity, transferring glycosyl groups Human DPM2 InterPro UniProtKB {GO:0006501=Reactome:REACT_1853, GO:0005515=PMID:10835346, GO:0004582=PMID:10835346, GO:0048471=GO_REF:0000019, GO:0033185=PMID:10835346, GO:0009059=GO_REF:0000002, GO:0019348=GO_REF:0000019, GO:0016254=Reactome:REACT_952, GO:0030176=GO_REF:0000002, GO:0000506=PMID:16280320, GO:0035269=PMID:16280320, GO:0031647=PMID:10835346, GO:0005789=Reactome:REACT_2036, GO:0030234=GO_REF:0000019, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0006506=PMID:10835346, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q5T9C7 Dolichol phosphate-mannose biosynthesis regulatory protein protein 20130413 {GO:0006501=TAS, GO:0005515=IPI, GO:0004582=IDA, GO:0048471=IEA, GO:0033185=IDA, GO:0009059=IEA, GO:0019348=IEA, GO:0016254=TAS, GO:0030176=IEA, GO:0000506=TAS, GO:0035269=TAS, GO:0031647=IPI, GO:0005789=TAS, GO:0030234=IEA, GO:0006488=TAS, GO:0044267=TAS, GO:0006506=IDA, GO:0043687=TAS, GO:0018279=TAS} C-terminal protein lipidation, GPI anchor biosynthetic process, cellular protein metabolic process, dolichol metabolic process, dolichol-linked oligosaccharide biosynthetic process, macromolecule biosynthetic process, post-translational protein modification, preassembly of GPI anchor in ER membrane, protein N-linked glycosylation via asparagine, protein O-linked mannosylation, regulation of protein stability dolichol-phosphate-mannose synthase complex, endoplasmic reticulum membrane, glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex, integral to endoplasmic reticulum membrane, perinuclear region of cytoplasm dolichyl-phosphate beta-D-mannosyltransferase activity, enzyme regulator activity, protein binding Human InterPro:IPR009914 DPM3 Reactome UniProtKB {GO:0006501=Reactome:REACT_1853, GO:0005515=PMID:10835346, GO:0004582=PMID:10835346, GO:0033185=PMID:10835346, GO:0005783=PMID:10835346, GO:0005975=PMID:10835346, GO:0018406=PMID:16280320, GO:0031501=PMID:16280320, GO:0030176=PMID:10835346, GO:0035269=PMID:16280320, GO:0035268=PMID:16280320, GO:0031647=PMID:10835346, GO:0005789=Reactome:REACT_2036, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0006506=PMID:16280320, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q9P2X0 Dolichol-phosphate mannosyltransferase subunit 3 protein 20130213 {GO:0006501=TAS, GO:0005515=IPI, GO:0004582=IDA, GO:0033185=IDA, GO:0005783=IDA, GO:0005975=NAS, GO:0018406=TAS, GO:0031501=TAS, GO:0030176=IDA, GO:0035269=TAS, GO:0035268=TAS, GO:0031647=IPI, GO:0005789=TAS, GO:0006488=TAS, GO:0044267=TAS, GO:0006506=TAS, GO:0043687=TAS, GO:0018279=TAS} C-terminal protein lipidation, GPI anchor biosynthetic process, carbohydrate metabolic process, cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan, protein N-linked glycosylation via asparagine, protein O-linked mannosylation, protein mannosylation, regulation of protein stability dolichol-phosphate-mannose synthase complex, endoplasmic reticulum, endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane, mannosyltransferase complex dolichyl-phosphate beta-D-mannosyltransferase activity, protein binding Human DPP10 MGI UniProtKB {GO:0016020=PMID:12662155, GO:0006508=GO_REF:0000002, GO:0008236=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0008239=PMID:12662155} Q8N608 Inactive dipeptidyl peptidase 10 protein 20120515 {GO:0016020=IDA, GO:0006508=IEA, GO:0008236=IEA, GO:0016021=IEA, GO:0008239=IDA} proteolysis integral to membrane, membrane dipeptidyl-peptidase activity, serine-type peptidase activity Human DPP3 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0004177=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0006508=PMID:10387075, GO:0005634=GO_REF:0000052, GO:0008270=PMID:10387075, GO:0008239=PMID:10387075, GO:0008237=GO_REF:0000037} Q9NY33 Dipeptidyl peptidase 3 protein 20110516 {GO:0005737=IDA, GO:0005886=IDA, GO:0004177=IEA, GO:0005730=IDA, GO:0006508=IDA, GO:0005634=IDA, GO:0008270=IDA, GO:0008239=IDA, GO:0008237=IEA} proteolysis cytoplasm, nucleolus, nucleus, plasma membrane aminopeptidase activity, dipeptidyl-peptidase activity, metallopeptidase activity, zinc ion binding Human DPP4 UniProtKB UniProtKB {GO:0005515=PMID:17287217, GO:0008284=PMID:17549790, GO:0004252=GO_REF:0000002, GO:0005886=PMID:16670267, GO:0031295=PMID:10900005, GO:0030139=PMID:10900005, GO:0002020=PMID:16651416, GO:0042803=PMID:14684150, GO:0010716=PMID:16651416, GO:0016324=PMID:15052268, GO:0046581=GO_REF:0000019, GO:0071438=PMID:16651416, GO:0006508=GO_REF:0000037, GO:0007155=GO_REF:0000037, GO:0001666=PMID:16670267, GO:0009986=PMID:10900005, GO:0031258=GO_REF:0000039, GO:0005102=PMID:10900005, GO:0033632=PMID:11772392, GO:0030027=PMID:16651416, GO:0042110=PMID:7594462, GO:0016020=GO_REF:0000002, GO:0043542=PMID:16651416, GO:0004177=GO_REF:0000037, GO:0008236=PMID:14684150, GO:0045121=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0008239=PMID:16651416} P27487 Dipeptidyl peptidase 4 protein 20091214 {GO:0005515=IPI, GO:0008284=IDA, GO:0004252=IEA, GO:0005886=IDA, GO:0031295=IDA, GO:0030139=IDA, GO:0002020=IPI, GO:0042803=IPI, GO:0010716=IDA, GO:0016324=IDA, GO:0046581=IEA, GO:0071438=IDA, GO:0006508=IEA, GO:0007155=IEA, GO:0001666=IDA, GO:0009986=IDA, GO:0031258=IEA, GO:0005102=IPI, GO:0033632=IDA, GO:0030027=IDA, GO:0042110=IDA, GO:0016020=IEA, GO:0043542=IDA, GO:0004177=IEA, GO:0008236=IDA, GO:0045121=IEA, GO:0016021=IEA, GO:0008239=IDA} T cell activation, T cell costimulation, cell adhesion, endothelial cell migration, negative regulation of extracellular matrix disassembly, positive regulation of cell proliferation, proteolysis, regulation of cell-cell adhesion mediated by integrin, response to hypoxia apical plasma membrane, cell surface, endocytic vesicle, integral to membrane, intercellular canaliculus, invadopodium membrane, lamellipodium, lamellipodium membrane, membrane, membrane raft, plasma membrane aminopeptidase activity, dipeptidyl-peptidase activity, protease binding, protein binding, protein homodimerization activity, receptor binding, serine-type endopeptidase activity, serine-type peptidase activity Human UniProtKB:Q03135 DPP6 PINC UniProtKB {GO:0008219=GO_REF:0000037, GO:0016020=GO_REF:0000002, GO:0006508=GO_REF:0000002, GO:0008236=GO_REF:0000002, GO:0043266=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0008239=PMID:8103397, GO:0019228=GO_REF:0000019} P42658 Dipeptidyl aminopeptidase-like protein 6 protein 20030904 {GO:0008219=IEA, GO:0016020=IEA, GO:0006508=IEA, GO:0008236=IEA, GO:0043266=IEA, GO:0016021=IEA, GO:0008239=TAS, GO:0019228=IEA} cell death, proteolysis, regulation of action potential in neuron, regulation of potassium ion transport integral to membrane, membrane dipeptidyl-peptidase activity, serine-type peptidase activity Human DPP7 UniProtKB UniProtKB {GO:0004177=GO_REF:0000037, GO:0006508=GO_REF:0000019, GO:0016023=GO_REF:0000039, GO:0008236=GO_REF:0000037, GO:0005576=GO_REF:0000039, GO:0008239=GO_REF:0000019, GO:0005764=GO_REF:0000039, GO:0005829=GO_REF:0000019} Q9UHL4 Dipeptidyl peptidase 2 protein 20130413 {GO:0004177=IEA, GO:0006508=IEA, GO:0016023=IEA, GO:0008236=IEA, GO:0005576=IEA, GO:0008239=IEA, GO:0005764=IEA, GO:0005829=IEA} proteolysis cytoplasmic membrane-bounded vesicle, cytosol, extracellular region, lysosome aminopeptidase activity, dipeptidyl-peptidase activity, serine-type peptidase activity Human UniProtKB-SubCell:SL-0088 DPP8 HPA UniProtKB {GO:0006955=PMID:11012666, GO:0005737=GO_REF:0000052, GO:0016020=GO_REF:0000002, GO:0004177=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0006508=PMID:11012666, GO:0008236=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0008239=PMID:11012666} Q6V1X1 Dipeptidyl peptidase 8 protein 20101115 {GO:0006955=TAS, GO:0005737=IDA, GO:0016020=IEA, GO:0004177=IEA, GO:0005730=IDA, GO:0006508=NAS, GO:0008236=IEA, GO:0005634=IDA, GO:0008239=NAS} immune response, proteolysis cytoplasm, membrane, nucleolus, nucleus aminopeptidase activity, dipeptidyl-peptidase activity, serine-type peptidase activity Human DPP9 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0016020=GO_REF:0000002, GO:0004177=GO_REF:0000037, GO:0006508=GO_REF:0000037, GO:0008236=GO_REF:0000037, GO:0005829=GO_REF:0000039} Q86TI2 Dipeptidyl peptidase 9 protein 20110516 {GO:0005737=IDA, GO:0016020=IEA, GO:0004177=IEA, GO:0006508=IEA, GO:0008236=IEA, GO:0005829=IEA} proteolysis cytoplasm, cytosol, membrane aminopeptidase activity, serine-type peptidase activity Human DPPA2 HPA UniProtKB {GO:0031060=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0019827=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:2000648=GO_REF:0000019, GO:0060484=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q7Z7J5 Developmental pluripotency-associated protein 2 protein 20110516 {GO:0031060=IEA, GO:0006355=IEA, GO:0019827=IEA, GO:0003682=IEA, GO:0005634=IDA, GO:2000648=IEA, GO:0060484=IEA, GO:0003676=IEA, GO:0006351=IEA} lung-associated mesenchyme development, positive regulation of stem cell proliferation, regulation of histone methylation, regulation of transcription, DNA-dependent, stem cell maintenance, transcription, DNA-dependent nucleus chromatin binding, nucleic acid binding Human DPPA3 UniProtKB UniProtKB {GO:2000653=GO_REF:0000024, GO:0005737=PMID:21421998, GO:0001939=GO_REF:0000024, GO:0040016=GO_REF:0000019, GO:1901536=GO_REF:0000024, GO:0005634=PMID:21421998, GO:0001940=GO_REF:0000024, GO:0035064=GO_REF:0000024, GO:0044726=GO_REF:0000024, GO:0016568=GO_REF:0000037} Q6W0C5 Developmental pluripotency-associated protein 3 protein 20121101 {GO:2000653=ISS, GO:0005737=IDA, GO:0001939=ISS, GO:0040016=IEA, GO:1901536=ISS, GO:0005634=IDA, GO:0001940=ISS, GO:0035064=ISS, GO:0044726=ISS, GO:0016568=IEA} chromatin modification, embryonic cleavage, negative regulation of DNA demethylation, protection of DNA demethylation of female pronucleus, regulation of genetic imprinting cytoplasm, female pronucleus, male pronucleus, nucleus methylated histone residue binding NOT Human UniProtKB:Q8QZY3 DPPA4 IntAct UniProtKB {GO:0005515=PMID:16169070, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q7L190 Developmental pluripotency-associated protein 4 protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0005634=IEA, GO:0007275=IEA, GO:0006351=IEA} multicellular organismal development, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus protein binding Human UniProtKB:Q99961 DPT BHF-UCL UniProtKB {GO:0031012=PMID:22261194, GO:0008285=GO_REF:0000019, GO:0030199=GO_REF:0000019, GO:0005578=GO_REF:0000039, GO:0007155=GO_REF:0000037} Q07507 Dermatopontin protein 20120228 {GO:0031012=ISS, GO:0008285=IEA, GO:0030199=IEA, GO:0005578=IEA, GO:0007155=IEA} cell adhesion, collagen fibril organization, negative regulation of cell proliferation extracellular matrix, proteinaceous extracellular matrix colocalizes_with Human UniProtKB:P45846 DPY19L1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q2PZI1 Protein dpy-19 homolog 1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 DPY19L3 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q6ZPD9 Protein dpy-19 homolog 3 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 DPY19L4 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q7Z388 Protein dpy-19 homolog 4 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 DPY30 HPA UniProtKB {GO:0005515=PMID:19556245, GO:0005802=PMID:19651892, GO:0006355=GO_REF:0000037, GO:0005794=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037, GO:0042803=PMID:19556245, GO:0042802=PMID:19556245, GO:0035097=PMID:17500065, GO:0048188=PMID:18838538, GO:0016197=PMID:19651892, GO:0051568=PMID:19556245} Q9C005 Protein dpy-30 homolog protein 20111111 {GO:0005515=IPI, GO:0005802=IDA, GO:0006355=IEA, GO:0005794=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006351=IEA, GO:0042803=IPI, GO:0042802=IPI, GO:0035097=IDA, GO:0048188=IDA, GO:0016197=IMP, GO:0051568=IDA} endosomal transport, histone H3-K4 methylation, regulation of transcription, DNA-dependent, transcription, DNA-dependent Golgi apparatus, Set1C/COMPASS complex, histone methyltransferase complex, nucleolus, nucleus, trans-Golgi network identical protein binding, protein binding, protein homodimerization activity NOT Human DPYD Reactome UniProtKB {GO:0050661=GO_REF:0000024, GO:0017113=Reactome:REACT_1067, GO:0006214=PMID:1512248, GO:0051539=GO_REF:0000037, GO:0051536=GO_REF:0000002, GO:0006210=PMID:10410956, GO:0050660=GO_REF:0000024, GO:0006212=PMID:18075467, GO:0006222=GO_REF:0000002, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0042803=GO_REF:0000024, GO:0005829=Reactome:REACT_1067, GO:0019483=GO_REF:0000041, GO:0046135=Reactome:REACT_1023, GO:0005737=PMID:1512248, GO:0006145=PMID:11988088, GO:0016491=GO_REF:0000002, GO:0006206=Reactome:REACT_957, GO:0004158=GO_REF:0000002, GO:0006208=GO_REF:0000024} Q12882 "Dihydropyrimidine dehydrogenase ""NADP(+)""" protein 20130213 {GO:0050661=ISS, GO:0017113=TAS, GO:0006214=IDA, GO:0051539=IEA, GO:0051536=IEA, GO:0006210=IDA, GO:0050660=ISS, GO:0006212=IDA, GO:0006222=IEA, GO:0055086=TAS, GO:0044281=TAS, GO:0046872=IEA, GO:0042803=ISS, GO:0005829=TAS, GO:0019483=IEA, GO:0046135=TAS, GO:0005737=IDA, GO:0006145=IMP, GO:0016491=IEA, GO:0006206=TAS, GO:0004158=IEA, GO:0006208=ISS} UMP biosynthetic process, beta-alanine biosynthetic process, nucleobase-containing small molecule metabolic process, purine nucleobase catabolic process, pyrimidine nucleobase catabolic process, pyrimidine nucleobase metabolic process, pyrimidine nucleoside catabolic process, small molecule metabolic process, thymidine catabolic process, thymine catabolic process, uracil catabolic process cytoplasm, cytosol 4 iron, 4 sulfur cluster binding, NADP binding, dihydroorotate oxidase activity, dihydropyrimidine dehydrogenase (NADP+) activity, flavin adenine dinucleotide binding, iron-sulfur cluster binding, metal ion binding, oxidoreductase activity, protein homodimerization activity Human DPYS Reactome UniProtKB {GO:0051219=GO_REF:0000019, GO:0016810=GO_REF:0000002, GO:0006210=GO_REF:0000024, GO:0006212=PMID:10410956, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0002059=GO_REF:0000019, GO:0002058=GO_REF:0000019, GO:0005829=Reactome:REACT_2169, GO:0019482=GO_REF:0000019, GO:0046135=Reactome:REACT_1023, GO:0051289=GO_REF:0000024, GO:0008270=PMID:9718352, GO:0016597=GO_REF:0000019, GO:0004157=Reactome:REACT_2169, GO:0006206=Reactome:REACT_957, GO:0006208=PMID:9718352} Q14117 Dihydropyrimidinase protein 20130213 {GO:0051219=IEA, GO:0016810=IEA, GO:0006210=ISS, GO:0006212=IDA, GO:0055086=TAS, GO:0044281=TAS, GO:0002059=IEA, GO:0002058=IEA, GO:0005829=TAS, GO:0019482=IEA, GO:0046135=TAS, GO:0051289=ISS, GO:0008270=NAS, GO:0016597=IEA, GO:0004157=TAS, GO:0006206=TAS, GO:0006208=IDA} beta-alanine metabolic process, nucleobase-containing small molecule metabolic process, protein homotetramerization, pyrimidine nucleobase catabolic process, pyrimidine nucleobase metabolic process, pyrimidine nucleoside catabolic process, small molecule metabolic process, thymine catabolic process, uracil catabolic process cytosol amino acid binding, dihydropyrimidinase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, phosphoprotein binding, thymine binding, uracil binding, zinc ion binding Human DPYSL2 Reactome UniProtKB {GO:0005515=PMID:19235893, GO:0030424=GO_REF:0000019, GO:0021510=GO_REF:0000019, GO:0016810=GO_REF:0000002, GO:0042220=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0030426=GO_REF:0000019, GO:0005829=Reactome:REACT_22358, GO:0014049=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0021772=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0007010=GO_REF:0000024, GO:0043025=GO_REF:0000019, GO:0019901=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0048489=GO_REF:0000019, GO:0007399=PMID:8973361, GO:0043234=GO_REF:0000019, GO:0007165=PMID:8973361, GO:0001975=GO_REF:0000019, GO:0006139=PMID:8973361, GO:0045664=GO_REF:0000019, GO:0004157=PMID:8973361, GO:0006208=GO_REF:0000002} Q16555 Dihydropyrimidinase-related protein 2 protein 20091012 {GO:0005515=IPI, GO:0030424=IEA, GO:0021510=IEA, GO:0016810=IEA, GO:0042220=IEA, GO:0030425=IEA, GO:0030426=IEA, GO:0005829=TAS, GO:0014049=IEA, GO:0005739=IEA, GO:0021772=IEA, GO:0007411=TAS, GO:0007010=ISS, GO:0043025=IEA, GO:0019901=IEA, GO:0042493=IEA, GO:0048489=IEA, GO:0007399=TAS, GO:0043234=IEA, GO:0007165=TAS, GO:0001975=IEA, GO:0006139=TAS, GO:0045664=IEA, GO:0004157=TAS, GO:0006208=IEA} axon guidance, cytoskeleton organization, nervous system development, nucleobase-containing compound metabolic process, olfactory bulb development, positive regulation of glutamate secretion, pyrimidine nucleobase catabolic process, regulation of neuron differentiation, response to amphetamine, response to cocaine, response to drug, signal transduction, spinal cord development, synaptic vesicle transport axon, cytosol, dendrite, growth cone, mitochondrion, neuronal cell body, protein complex dihydropyrimidinase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, protein binding, protein kinase binding Human DPYSL3 Reactome UniProtKB {GO:0051219=GO_REF:0000019, GO:0017124=GO_REF:0000024, GO:0016810=GO_REF:0000002, GO:0016812=GO_REF:0000002, GO:0051491=GO_REF:0000024, GO:0005615=GO_REF:0000024, GO:0048678=GO_REF:0000024, GO:0035374=GO_REF:0000024, GO:0030426=GO_REF:0000024, GO:0005829=Reactome:REACT_19321, GO:0048666=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0051260=GO_REF:0000024, GO:0051764=GO_REF:0000024, GO:0051017=GO_REF:0000024, GO:0030336=GO_REF:0000024, GO:0044297=GO_REF:0000024, GO:0030027=GO_REF:0000024, GO:0031941=GO_REF:0000024, GO:0016787=GO_REF:0000002, GO:0071345=GO_REF:0000024, GO:0010976=GO_REF:0000024, GO:0010977=GO_REF:0000024, GO:0070382=GO_REF:0000024, GO:0006208=GO_REF:0000002} Q14195 Dihydropyrimidinase-related protein 3 protein 20130301 {GO:0051219=IEA, GO:0017124=ISS, GO:0016810=IEA, GO:0016812=IEA, GO:0051491=ISS, GO:0005615=ISS, GO:0048678=ISS, GO:0035374=ISS, GO:0030426=ISS, GO:0005829=TAS, GO:0048666=IEA, GO:0007411=TAS, GO:0051260=ISS, GO:0051764=ISS, GO:0051017=ISS, GO:0030336=ISS, GO:0044297=ISS, GO:0030027=ISS, GO:0031941=ISS, GO:0016787=IEA, GO:0071345=ISS, GO:0010976=ISS, GO:0010977=ISS, GO:0070382=ISS, GO:0006208=IEA} actin crosslink formation, actin filament bundle assembly, axon guidance, cellular response to cytokine stimulus, negative regulation of cell migration, negative regulation of neuron projection development, neuron development, positive regulation of filopodium assembly, positive regulation of neuron projection development, protein homooligomerization, pyrimidine nucleobase catabolic process, response to axon injury cell body, cytosol, exocytic vesicle, extracellular space, filamentous actin, growth cone, lamellipodium SH3 domain binding, chondroitin sulfate binding, hydrolase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides, phosphoprotein binding Human DPYSL4 InterPro UniProtKB {GO:0016787=GO_REF:0000002, GO:0007411=Reactome:REACT_18266, GO:0016812=GO_REF:0000002, GO:0005829=Reactome:REACT_19321, GO:0007399=PMID:9652388, GO:0006208=GO_REF:0000002} Q5T0Q6 Dihydropyrimidinase-related protein 4 protein 20130413 {GO:0016787=IEA, GO:0007411=TAS, GO:0016812=IEA, GO:0005829=TAS, GO:0007399=TAS, GO:0006208=IEA} axon guidance, nervous system development, pyrimidine nucleobase catabolic process cytosol hydrolase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides Human InterPro:IPR006680 DPYSL5 Reactome UniProtKB {GO:0007165=PMID:10851247, GO:0043234=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0016810=GO_REF:0000002, GO:0007411=Reactome:REACT_18266, GO:0016812=GO_REF:0000002, GO:0030182=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0005829=Reactome:REACT_19321, GO:0007399=PMID:10851247, GO:0006208=GO_REF:0000002} Q9BPU6 Dihydropyrimidinase-related protein 5 protein 20130301 {GO:0007165=TAS, GO:0043234=IEA, GO:0005737=IEA, GO:0016810=IEA, GO:0007411=TAS, GO:0016812=IEA, GO:0030182=IEA, GO:0043025=IEA, GO:0030425=IEA, GO:0005829=TAS, GO:0007399=TAS, GO:0006208=IEA} axon guidance, nervous system development, neuron differentiation, pyrimidine nucleobase catabolic process, signal transduction cytoplasm, cytosol, dendrite, neuronal cell body, protein complex hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides Human DQX1 UniProtKB UniProtKB {GO:0004386=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q8TE96 ATP-dependent RNA helicase DQX1 protein 20130413 {GO:0004386=IEA, GO:0005634=IEA, GO:0003676=IEA, GO:0005524=IEA} nucleus ATP binding, helicase activity, nucleic acid binding Human UniProtKB-SubCell:SL-0191 DR1 BHF-UCL UniProtKB {GO:0005515=PMID:18838386, GO:0043565=GO_REF:0000002, GO:0043966=PMID:18838386, GO:0046982=GO_REF:0000002, GO:0003714=PMID:8670811, GO:0017025=PMID:18838386, GO:0005671=PMID:18838386, GO:0000122=PMID:8670811, GO:0003677=PMID:8670811, GO:0006351=GO_REF:0000037, GO:0008134=PMID:1339312} Q01658 Protein Dr1 protein 20101105 {GO:0005515=IPI, GO:0043565=IEA, GO:0043966=IDA, GO:0046982=IEA, GO:0003714=TAS, GO:0017025=IDA, GO:0005671=IDA, GO:0000122=TAS, GO:0003677=TAS, GO:0006351=IEA, GO:0008134=TAS} histone H3 acetylation, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent Ada2/Gcn5/Ada3 transcription activator complex DNA binding, TBP-class protein binding, protein binding, protein heterodimerization activity, sequence-specific DNA binding, transcription corepressor activity, transcription factor binding Human DRAM1 UniProtKB UniProtKB {GO:0006914=GO_REF:0000037, GO:0006915=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005765=GO_REF:0000039} Q8N682 DNA damage-regulated autophagy modulator protein 1 protein 20130413 {GO:0006914=IEA, GO:0006915=IEA, GO:0016021=IEA, GO:0005765=IEA} apoptotic process, autophagy integral to membrane, lysosomal membrane Human UniProtKB-SubCell:SL-0157 DRAM2 HPA UniProtKB {GO:0005794=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0006917=PMID:19895784, GO:0016021=GO_REF:0000037, GO:0005765=GO_REF:0000039, GO:0005764=PMID:19556885, GO:0043231=GO_REF:0000052} Q6UX65 DNA damage-regulated autophagy modulator protein 2 protein 20090616 {GO:0005794=IDA, GO:0006915=IEA, GO:0006917=IDA, GO:0016021=IEA, GO:0005765=IEA, GO:0005764=IDA, GO:0043231=IDA} apoptotic process, induction of apoptosis Golgi apparatus, integral to membrane, intracellular membrane-bounded organelle, lysosomal membrane, lysosome Human DRAP1 PINC UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=PMID:8608938, GO:0046982=GO_REF:0000002, GO:0003714=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0000122=GO_REF:0000019, GO:0003677=PMID:8670811, GO:0006351=GO_REF:0000037, GO:0008134=GO_REF:0000019} Q14919 Dr1-associated corepressor protein 20050308 {GO:0043565=IEA, GO:0003700=TAS, GO:0046982=IEA, GO:0003714=IEA, GO:0005634=IEA, GO:0000122=IEA, GO:0003677=TAS, GO:0006351=IEA, GO:0008134=IEA} negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding, protein heterodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity, transcription factor binding Human DRD1 BHF-UCL UniProtKB {GO:0005515=PMID:15569306, GO:0001659=GO_REF:0000019, GO:0043268=GO_REF:0000024, GO:0060291=GO_REF:0000019, GO:0060292=GO_REF:0000019, GO:0006606=GO_REF:0000019, GO:0019226=GO_REF:0000024, GO:0019228=GO_REF:0000019, GO:0051584=PMID:8301582, GO:0046323=GO_REF:0000019, GO:0051482=PMID:1282671, GO:0001662=GO_REF:0000019, GO:0007613=GO_REF:0000019, GO:0001661=GO_REF:0000019, GO:0021542=GO_REF:0000019, GO:0001588=PMID:2168520, GO:0030335=GO_REF:0000024, GO:0007617=GO_REF:0000024, GO:0060134=GO_REF:0000024, GO:0051968=GO_REF:0000024, GO:0035240=PMID:1282671, GO:0030432=GO_REF:0000019, GO:0007416=GO_REF:0000024, GO:0005887=PMID:2144334, GO:0007187=PMID:1282671, GO:0071870=PMID:18403039, GO:0008542=GO_REF:0000024, GO:0005789=GO_REF:0000039, GO:0097458=GO_REF:0000002, GO:0007189=PMID:2144334, GO:0005886=PMID:15569306, GO:0030819=PMID:7838121, GO:0048148=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0042053=GO_REF:0000019, GO:0007191=PMID:18403039, GO:0007190=PMID:2168520, GO:0042417=PMID:8301582, GO:0042311=GO_REF:0000002, GO:0001963=GO_REF:0000019, GO:0007628=GO_REF:0000024, GO:0035106=GO_REF:0000019, GO:0007625=GO_REF:0000019, GO:0051281=PMID:7838121, GO:0015872=GO_REF:0000019, GO:0042493=GO_REF:0000024, GO:0004952=PMID:1831904, GO:0046960=GO_REF:0000019, GO:0010579=GO_REF:0000002, GO:0021853=GO_REF:0000024, GO:0021756=GO_REF:0000019, GO:0001975=GO_REF:0000019, GO:0014002=GO_REF:0000019, GO:0060158=PMID:1282671} P21728 D(1A) dopamine receptor protein 20120329 {GO:0005515=IPI, GO:0001659=IEA, GO:0043268=ISS, GO:0060291=IEA, GO:0060292=IEA, GO:0006606=IEA, GO:0019226=ISS, GO:0019228=IEA, GO:0051584=IC, GO:0046323=IEA, GO:0051482=IDA, GO:0001662=IEA, GO:0007613=IEA, GO:0001661=IEA, GO:0021542=IEA, GO:0001588=IDA, GO:0030335=ISS, GO:0007617=ISS, GO:0060134=ISS, GO:0051968=ISS, GO:0035240=IMP, GO:0030432=IEA, GO:0007416=ISS, GO:0005887=IC, GO:0007187=IDA, GO:0071870=IDA, GO:0008542=ISS, GO:0005789=IEA, GO:0097458=IEA, GO:0007189=IDA, GO:0005886=IDA, GO:0030819=IDA, GO:0048148=IEA, GO:0005634=IEA, GO:0042053=IEA, GO:0007191=IDA, GO:0007190=IDA, GO:0042417=IC, GO:0042311=IEA, GO:0001963=IEA, GO:0007628=ISS, GO:0035106=IEA, GO:0007625=IEA, GO:0051281=IDA, GO:0015872=IEA, GO:0042493=ISS, GO:0004952=IDA, GO:0046960=IEA, GO:0010579=IEA, GO:0021853=ISS, GO:0021756=IEA, GO:0001975=IEA, GO:0014002=IEA, GO:0060158=IDA} G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, activation of adenylate cyclase activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-activating dopamine receptor signaling pathway, adult walking behavior, astrocyte development, behavioral fear response, behavioral response to cocaine, cellular response to catecholamine stimulus, cerebral cortex GABAergic interneuron migration, conditioned taste aversion, dentate gyrus development, dopamine metabolic process, dopamine transport, elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway, glucose import, grooming behavior, long term synaptic depression, long-term synaptic potentiation, mating behavior, memory, operant conditioning, peristalsis, phospholipase C-activating dopamine receptor signaling pathway, positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway, positive regulation of cAMP biosynthetic process, positive regulation of cell migration, positive regulation of potassium ion transport, positive regulation of release of sequestered calcium ion into cytosol, positive regulation of synaptic transmission, glutamatergic, prepulse inhibition, protein import into nucleus, regulation of action potential in neuron, regulation of dopamine metabolic process, regulation of dopamine uptake involved in synaptic transmission, response to amphetamine, response to drug, sensitization, striatum development, synapse assembly, synaptic transmission, dopaminergic, temperature homeostasis, transmission of nerve impulse, vasodilation, visual learning endoplasmic reticulum membrane, integral to plasma membrane, neuron part, nucleus, plasma membrane dopamine binding, dopamine neurotransmitter receptor activity, dopamine neurotransmitter receptor activity, coupled via Gs, protein binding Human DRD2 ENSEMBL UniProtKB {GO:0005515=PMID:10692483, GO:0043266=GO_REF:0000019, GO:0030672=GO_REF:0000019, GO:0016055=GO_REF:0000019, GO:0046676=GO_REF:0000019, GO:0008306=GO_REF:0000024, GO:0045745=GO_REF:0000019, GO:0051209=GO_REF:0000019, GO:0051967=GO_REF:0000019, GO:0060134=GO_REF:0000019, GO:0046488=GO_REF:0000019, GO:0009636=GO_REF:0000019, GO:0035240=GO_REF:0000019, GO:0043278=GO_REF:0000019, GO:0007270=GO_REF:0000024, GO:0005887=GO_REF:0000002, GO:0035815=GO_REF:0000019, GO:0001591=GO_REF:0000019, GO:0035810=GO_REF:0000019, GO:0034776=PMID:16839358, GO:0021984=GO_REF:0000019, GO:0060124=GO_REF:0000019, GO:0007631=GO_REF:0000019, GO:0030424=GO_REF:0000024, GO:0048148=GO_REF:0000019, GO:0007195=GO_REF:0000019, GO:0007194=GO_REF:0000019, GO:0030425=GO_REF:0000024, GO:0046717=GO_REF:0000019, GO:0042417=GO_REF:0000019, GO:0008144=GO_REF:0000019, GO:0001963=GO_REF:0000019, GO:0007628=GO_REF:0000019, GO:0043204=GO_REF:0000019, GO:0007626=GO_REF:0000024, GO:0030815=GO_REF:0000002, GO:0007625=GO_REF:0000019, GO:0030814=PMID:8666994, GO:0040018=GO_REF:0000019, GO:0014854=GO_REF:0000019, GO:0050482=PMID:8301582, GO:0042493=GO_REF:0000019, GO:0004952=GO_REF:0000002, GO:0021853=GO_REF:0000019, GO:0001975=GO_REF:0000019, GO:0001976=GO_REF:0000019, GO:0042321=GO_REF:0000019, GO:0048149=GO_REF:0000019, GO:0048755=GO_REF:0000019, GO:0002092=GO_REF:0000019, GO:0035094=GO_REF:0000019, GO:0007608=GO_REF:0000019, GO:0001659=GO_REF:0000019, GO:0007409=GO_REF:0000019, GO:0042220=GO_REF:0000024, GO:0048678=GO_REF:0000019, GO:0042221=GO_REF:0000002, GO:0031223=GO_REF:0000019, GO:0051584=PMID:8301582, GO:0051586=GO_REF:0000019, GO:0010039=GO_REF:0000019, GO:0048169=GO_REF:0000019, GO:0009416=GO_REF:0000024, GO:0070374=GO_REF:0000019, GO:0030336=GO_REF:0000019, GO:0007616=GO_REF:0000019, GO:1901386=GO_REF:0000019, GO:0014069=GO_REF:0000019, GO:0007416=GO_REF:0000019, GO:0030432=GO_REF:0000019, GO:0002031=GO_REF:0000019, GO:0032922=GO_REF:0000019, GO:0002027=GO_REF:0000019, GO:0008542=GO_REF:0000019, GO:0032228=GO_REF:0000019, GO:0002028=GO_REF:0000019, GO:0050709=PMID:16839358, GO:0097458=GO_REF:0000002, GO:0051898=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0005886=Reactome:REACT_22289, GO:0030139=GO_REF:0000019, GO:0045776=GO_REF:0000019, GO:0014059=GO_REF:0000019, GO:0032147=GO_REF:0000019, GO:0008104=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0043679=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0060160=GO_REF:0000019, GO:0001669=GO_REF:0000019, GO:0051481=GO_REF:0000019, GO:0002052=GO_REF:0000019, GO:0016328=GO_REF:0000019, GO:0035255=GO_REF:0000019, GO:0060158=GO_REF:0000019, GO:0043473=GO_REF:0000019, GO:0043666=GO_REF:0000019} Q6LDH7 D(2) dopamine receptor protein 20130413 {GO:0005515=IPI, GO:0043266=IEA, GO:0030672=IEA, GO:0016055=IEA, GO:0046676=IEA, GO:0008306=ISS, GO:0045745=IEA, GO:0051209=IEA, GO:0051967=IEA, GO:0060134=IEA, GO:0046488=IEA, GO:0009636=IEA, GO:0035240=IEA, GO:0043278=IEA, GO:0007270=ISS, GO:0005887=IEA, GO:0035815=IEA, GO:0001591=IEA, GO:0035810=IEA, GO:0034776=IDA, GO:0021984=IEA, GO:0060124=IEA, GO:0007631=IEA, GO:0030424=ISS, GO:0048148=IEA, GO:0007195=IEA, GO:0007194=IEA, GO:0030425=ISS, GO:0046717=IEA, GO:0042417=IEA, GO:0008144=IEA, GO:0001963=IEA, GO:0007628=IEA, GO:0043204=IEA, GO:0007626=ISS, GO:0030815=IEA, GO:0007625=IEA, GO:0030814=IDA, GO:0040018=IEA, GO:0014854=IEA, GO:0050482=IDA, GO:0042493=IEA, GO:0004952=IEA, GO:0021853=IEA, GO:0001975=IEA, GO:0001976=IEA, GO:0042321=IEA, GO:0048149=IEA, GO:0048755=IEA, GO:0002092=IEA, GO:0035094=IEA, GO:0007608=IEA, GO:0001659=IEA, GO:0007409=IEA, GO:0042220=ISS, GO:0048678=IEA, GO:0042221=IEA, GO:0031223=IEA, GO:0051584=IC, GO:0051586=IEA, GO:0010039=IEA, GO:0048169=IEA, GO:0009416=ISS, GO:0070374=IEA, GO:0030336=IEA, GO:0007616=IEA, GO:1901386=IEA, GO:0014069=IEA, GO:0007416=IEA, GO:0030432=IEA, GO:0002031=IEA, GO:0032922=IEA, GO:0002027=IEA, GO:0008542=IEA, GO:0032228=IEA, GO:0002028=IEA, GO:0050709=IDA, GO:0097458=IEA, GO:0051898=IEA, GO:0008285=IEA, GO:0005886=TAS, GO:0030139=IEA, GO:0045776=IEA, GO:0014059=IEA, GO:0032147=IEA, GO:0008104=IEA, GO:0045944=IEA, GO:0043679=IEA, GO:0001666=IEA, GO:0060160=IEA, GO:0001669=IEA, GO:0051481=IEA, GO:0002052=IEA, GO:0016328=IEA, GO:0035255=IEA, GO:0060158=IEA, GO:0043473=IEA, GO:0043666=IEA} G-protein coupled receptor internalization, Wnt receptor signaling pathway, acid secretion, activation of protein kinase activity, adenohypophysis development, adenylate cyclase-inhibiting dopamine receptor signaling pathway, adult walking behavior, arachidonic acid secretion, associative learning, auditory behavior, axonogenesis, behavioral response to cocaine, behavioral response to ethanol, branching morphogenesis of a nerve, cerebral cortex GABAergic interneuron migration, circadian regulation of gene expression, dopamine metabolic process, feeding behavior, grooming behavior, locomotory behavior, long-term memory, negative regulation of adenylate cyclase activity, negative regulation of blood pressure, negative regulation of cAMP metabolic process, negative regulation of cell migration, negative regulation of cell proliferation, negative regulation of circadian sleep/wake cycle, sleep, negative regulation of dopamine receptor signaling pathway, negative regulation of insulin secretion, negative regulation of protein kinase B signaling cascade, negative regulation of protein secretion, negative regulation of synaptic transmission, glutamatergic, negative regulation of voltage-gated calcium channel activity, neurological system process involved in regulation of systemic arterial blood pressure, neuron-neuron synaptic transmission, peristalsis, phosphatidylinositol metabolic process, phospholipase C-activating dopamine receptor signaling pathway, pigmentation, positive regulation of ERK1 and ERK2 cascade, positive regulation of G-protein coupled receptor protein signaling pathway, positive regulation of dopamine uptake involved in synaptic transmission, positive regulation of growth hormone secretion, positive regulation of multicellular organism growth, positive regulation of neuroblast proliferation, positive regulation of receptor internalization, positive regulation of renal sodium excretion, positive regulation of transcription from RNA polymerase II promoter, positive regulation of urine volume, prepulse inhibition, protein localization, reduction of cytosolic calcium ion concentration, regulation of cAMP metabolic process, regulation of dopamine secretion, regulation of dopamine uptake involved in synaptic transmission, regulation of heart rate, regulation of long-term neuronal synaptic plasticity, regulation of phosphoprotein phosphatase activity, regulation of potassium ion transport, regulation of sodium ion transport, regulation of synaptic transmission, GABAergic, release of sequestered calcium ion into cytosol, response to amphetamine, response to axon injury, response to chemical stimulus, response to cocaine, response to drug, response to histamine, response to hypoxia, response to inactivity, response to iron ion, response to light stimulus, response to morphine, response to nicotine, response to toxic substance, sensory perception of smell, synapse assembly, synaptic transmission, dopaminergic, temperature homeostasis, visual learning acrosomal vesicle, axon, axon terminus, dendrite, endocytic vesicle, integral to plasma membrane, lateral plasma membrane, neuron part, perikaryon, plasma membrane, postsynaptic density, synaptic vesicle membrane dopamine binding, dopamine neurotransmitter receptor activity, dopamine neurotransmitter receptor activity, coupled via Gi/Go, drug binding, ionotropic glutamate receptor binding, protein binding Human Ensembl:ENSRNOP00000043759 DRD3 BHF-UCL UniProtKB {GO:0005515=PMID:10692483, GO:0032416=GO_REF:0000019, GO:0042995=GO_REF:0000019, GO:0042220=PMID:10415668, GO:0042221=GO_REF:0000002, GO:0051584=PMID:8301582, GO:0002016=GO_REF:0000019, GO:0050883=GO_REF:0000024, GO:0007611=PMID:14681904, GO:0007612=PMID:15998189, GO:0060134=PMID:18325483, GO:0019904=GO_REF:0000019, GO:0035240=GO_REF:0000019, GO:0045840=GO_REF:0000024, GO:0043278=GO_REF:0000024, GO:0000122=GO_REF:0000019, GO:0002031=PMID:18424554, GO:0032922=GO_REF:0000024, GO:0019216=GO_REF:0000019, GO:0007186=PMID:7911712, GO:0005887=PMID:8413587, GO:0008542=GO_REF:0000024, GO:0035815=GO_REF:0000019, GO:0035176=PMID:12860355, GO:0001591=GO_REF:0000024, GO:0050709=PMID:16839358, GO:0034776=PMID:16839358, GO:0051898=GO_REF:0000024, GO:0008284=GO_REF:0000019, GO:0005886=PMID:18424554, GO:0045471=GO_REF:0000024, GO:0045187=GO_REF:0000019, GO:0048148=GO_REF:0000024, GO:0030139=GO_REF:0000019, GO:0045776=GO_REF:0000024, GO:0007195=PMID:18424554, GO:0007194=PMID:7907363, GO:0014059=GO_REF:0000024, GO:0046717=GO_REF:0000024, GO:0007191=PMID:18424554, GO:0040012=GO_REF:0000019, GO:0042417=PMID:8301582, GO:0045944=GO_REF:0000019, GO:0008144=PMID:8413587, GO:0040014=GO_REF:0000019, GO:0001963=GO_REF:0000019, GO:0030815=GO_REF:0000002, GO:0007626=GO_REF:0000024, GO:0030814=PMID:8666994, GO:0060161=GO_REF:0000024, GO:0050482=PMID:8301582, GO:0060160=GO_REF:0000019, GO:0042493=GO_REF:0000024, GO:0006874=PMID:7911712, GO:0004952=GO_REF:0000002, GO:0045177=GO_REF:0000019, GO:0001975=GO_REF:0000019, GO:0048715=GO_REF:0000024} P35462 D(3) dopamine receptor protein 20080903 {GO:0005515=IPI, GO:0032416=IEA, GO:0042995=IEA, GO:0042220=IEP, GO:0042221=IEA, GO:0051584=IC, GO:0002016=IEA, GO:0050883=ISS, GO:0007611=NAS, GO:0007612=NAS, GO:0060134=IMP, GO:0019904=IEA, GO:0035240=IEA, GO:0045840=ISS, GO:0043278=ISS, GO:0000122=IEA, GO:0002031=IDA, GO:0032922=ISS, GO:0019216=IEA, GO:0007186=IDA, GO:0005887=IDA, GO:0008542=ISS, GO:0035815=IEA, GO:0035176=NAS, GO:0001591=ISS, GO:0050709=IDA, GO:0034776=IDA, GO:0051898=ISS, GO:0008284=IEA, GO:0005886=IDA, GO:0045471=ISS, GO:0045187=IEA, GO:0048148=ISS, GO:0030139=IEA, GO:0045776=ISS, GO:0007195=IDA, GO:0007194=IDA, GO:0014059=ISS, GO:0046717=ISS, GO:0007191=IDA, GO:0040012=IEA, GO:0042417=IC, GO:0045944=IEA, GO:0008144=IDA, GO:0040014=IEA, GO:0001963=IEA, GO:0030815=IEA, GO:0007626=ISS, GO:0030814=IDA, GO:0060161=ISS, GO:0050482=IDA, GO:0060160=IEA, GO:0042493=ISS, GO:0006874=IDA, GO:0004952=IEA, GO:0045177=IEA, GO:0001975=IEA, GO:0048715=ISS} G-protein coupled receptor internalization, G-protein coupled receptor signaling pathway, acid secretion, adenylate cyclase-activating dopamine receptor signaling pathway, adenylate cyclase-inhibiting dopamine receptor signaling pathway, arachidonic acid secretion, behavioral response to cocaine, cellular calcium ion homeostasis, circadian regulation of gene expression, dopamine metabolic process, learning, learning or memory, locomotory behavior, musculoskeletal movement, spinal reflex action, negative regulation of adenylate cyclase activity, negative regulation of blood pressure, negative regulation of cAMP metabolic process, negative regulation of dopamine receptor signaling pathway, negative regulation of oligodendrocyte differentiation, negative regulation of protein kinase B signaling cascade, negative regulation of protein secretion, negative regulation of sodium:hydrogen antiporter activity, negative regulation of transcription from RNA polymerase II promoter, positive regulation of cell proliferation, positive regulation of dopamine receptor signaling pathway, positive regulation of mitosis, positive regulation of renal sodium excretion, positive regulation of transcription from RNA polymerase II promoter, prepulse inhibition, regulation of blood volume by renin-angiotensin, regulation of cAMP metabolic process, regulation of circadian sleep/wake cycle, sleep, regulation of dopamine secretion, regulation of dopamine uptake involved in synaptic transmission, regulation of lipid metabolic process, regulation of locomotion, regulation of multicellular organism growth, response to amphetamine, response to chemical stimulus, response to cocaine, response to drug, response to ethanol, response to histamine, response to morphine, social behavior, synaptic transmission, dopaminergic, visual learning apical part of cell, cell projection, endocytic vesicle, integral to plasma membrane, plasma membrane dopamine binding, dopamine neurotransmitter receptor activity, dopamine neurotransmitter receptor activity, coupled via Gi/Go, drug binding, protein binding, protein domain specific binding Human UniProtKB:P19020 DRD4 BHF-UCL UniProtKB {GO:0005515=PMID:12297500, GO:0008344=GO_REF:0000024, GO:0017124=PMID:9843378, GO:0032417=PMID:7512953, GO:0005886=Reactome:REACT_22289, GO:0030818=PMID:7512953, GO:0048148=GO_REF:0000024, GO:0015459=PMID:12297500, GO:0007195=PMID:7512953, GO:0007194=PMID:7512953, GO:0042053=GO_REF:0000024, GO:0042596=GO_REF:0000024, GO:0000187=PMID:15755724, GO:0042417=PMID:1840645, GO:0043197=GO_REF:0000019, GO:0051586=PMID:1840645, GO:0008144=PMID:8413587, GO:0043195=GO_REF:0000019, GO:0001963=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0001662=PMID:12860355, GO:0005938=GO_REF:0000019, GO:0050482=PMID:7512953, GO:0050848=GO_REF:0000019, GO:0012506=GO_REF:0000019, GO:0033674=PMID:15755724, GO:0008355=GO_REF:0000019, GO:0007614=GO_REF:0000019, GO:0004952=PMID:8413587, GO:0006874=PMID:7921596, GO:0046928=GO_REF:0000019, GO:1901386=PMID:7921596, GO:0035240=PMID:1319557, GO:0007212=PMID:1840645, GO:0001975=GO_REF:0000024, GO:0060080=GO_REF:0000024, GO:0016020=PMID:7512953, GO:0005887=PMID:15755724, GO:0048149=PMID:12888781, GO:0035176=PMID:11409696, GO:0050709=PMID:16839358, GO:0001591=GO_REF:0000024, GO:0034776=PMID:16839358} P21917 D(4) dopamine receptor protein 20080903 {GO:0005515=IPI, GO:0008344=ISS, GO:0017124=IDA, GO:0032417=IDA, GO:0005886=TAS, GO:0030818=IDA, GO:0048148=ISS, GO:0015459=NAS, GO:0007195=IDA, GO:0007194=IDA, GO:0042053=ISS, GO:0042596=ISS, GO:0000187=IDA, GO:0042417=IC, GO:0043197=IEA, GO:0051586=IC, GO:0008144=IDA, GO:0043195=IEA, GO:0001963=IEA, GO:0043025=IEA, GO:0001662=NAS, GO:0005938=IEA, GO:0050482=IDA, GO:0050848=IEA, GO:0012506=IEA, GO:0033674=IDA, GO:0008355=IEA, GO:0007614=IEA, GO:0004952=IDA, GO:0006874=IC, GO:0046928=IEA, GO:1901386=IDA, GO:0035240=IDA, GO:0007212=IDA, GO:0001975=ISS, GO:0060080=ISS, GO:0016020=IDA, GO:0005887=IDA, GO:0048149=TAS, GO:0035176=NAS, GO:0050709=IDA, GO:0001591=ISS, GO:0034776=IDA} activation of MAPK activity, adenylate cyclase-inhibiting dopamine receptor signaling pathway, adult locomotory behavior, arachidonic acid secretion, behavioral fear response, behavioral response to cocaine, behavioral response to ethanol, cellular calcium ion homeostasis, dopamine metabolic process, dopamine receptor signaling pathway, fear response, negative regulation of adenylate cyclase activity, negative regulation of cAMP biosynthetic process, negative regulation of protein secretion, negative regulation of voltage-gated calcium channel activity, olfactory learning, positive regulation of dopamine uptake involved in synaptic transmission, positive regulation of kinase activity, positive regulation of sodium:hydrogen antiporter activity, regulation of calcium-mediated signaling, regulation of dopamine metabolic process, regulation of inhibitory postsynaptic membrane potential, regulation of neurotransmitter secretion, response to amphetamine, response to histamine, short-term memory, social behavior, synaptic transmission, dopaminergic cell cortex, dendritic spine, integral to plasma membrane, membrane, neuronal cell body, plasma membrane, terminal bouton, vesicle membrane SH3 domain binding, dopamine binding, dopamine neurotransmitter receptor activity, dopamine neurotransmitter receptor activity, coupled via Gi/Go, drug binding, potassium channel regulator activity, protein binding Human DRD5 BHF-UCL UniProtKB {GO:0005886=Reactome:REACT_22268, GO:0007268=PMID:7727453, GO:0060292=GO_REF:0000019, GO:0045776=GO_REF:0000019, GO:0031526=GO_REF:0000019, GO:0042220=GO_REF:0000019, GO:0001992=GO_REF:0000019, GO:0007191=PMID:18403039, GO:0007190=PMID:9457173, GO:0001963=PMID:11036203, GO:0033861=PMID:16352863, GO:0045924=GO_REF:0000019, GO:0008306=GO_REF:0000019, GO:0001588=PMID:9457173, GO:0072593=PMID:16352863, GO:0004952=PMID:1826762, GO:0006874=PMID:9457173, GO:0046960=GO_REF:0000019, GO:0010579=GO_REF:0000002, GO:0035240=PMID:1826762, GO:0045762=PMID:1826762, GO:0001975=GO_REF:0000019, GO:0001994=GO_REF:0000019, GO:0005887=PMID:9457173, GO:0071870=PMID:18403039, GO:0042060=GO_REF:0000019, GO:0060158=PMID:9457173, GO:0007189=PMID:11500503} P21918 D(1B) dopamine receptor protein 20120329 {GO:0005886=TAS, GO:0007268=NAS, GO:0060292=IEA, GO:0045776=IEA, GO:0031526=IEA, GO:0042220=IEA, GO:0001992=IEA, GO:0007191=IDA, GO:0007190=TAS, GO:0001963=NAS, GO:0033861=IDA, GO:0045924=IEA, GO:0008306=IEA, GO:0001588=TAS, GO:0072593=IDA, GO:0004952=IDA, GO:0006874=TAS, GO:0046960=IEA, GO:0010579=IEA, GO:0035240=IDA, GO:0045762=IDA, GO:0001975=IEA, GO:0001994=IEA, GO:0005887=TAS, GO:0071870=IDA, GO:0042060=IEA, GO:0060158=TAS, GO:0007189=IDA} activation of adenylate cyclase activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-activating dopamine receptor signaling pathway, associative learning, cellular calcium ion homeostasis, cellular response to catecholamine stimulus, long term synaptic depression, negative regulation of NAD(P)H oxidase activity, negative regulation of blood pressure, norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure, phospholipase C-activating dopamine receptor signaling pathway, positive regulation of adenylate cyclase activity, positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway, reactive oxygen species metabolic process, regulation of female receptivity, regulation of systemic arterial blood pressure by vasopressin, response to amphetamine, response to cocaine, sensitization, synaptic transmission, synaptic transmission, dopaminergic, wound healing brush border membrane, integral to plasma membrane, plasma membrane dopamine binding, dopamine neurotransmitter receptor activity, dopamine neurotransmitter receptor activity, coupled via Gs Human DRG1 HPA UniProtKB {GO:0005515=PMID:16189514, GO:0005737=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0007275=PMID:1280421, GO:0045111=GO_REF:0000052, GO:0005525=GO_REF:0000037, GO:0005844=PMID:19819225, GO:0006351=PMID:9824680, GO:0008134=PMID:9824680} Q9Y295 Developmentally-regulated GTP-binding protein 1 protein 20080818 {GO:0005515=IPI, GO:0005737=IDA, GO:0005634=IDA, GO:0007275=TAS, GO:0045111=IDA, GO:0005525=IEA, GO:0005844=IDA, GO:0006351=TAS, GO:0008134=TAS} multicellular organismal development, transcription, DNA-dependent cytoplasm, intermediate filament cytoskeleton, nucleus, polysome GTP binding, protein binding, transcription factor binding Human DRG2 HPA UniProtKB {GO:0005739=GO_REF:0000019, GO:0007165=PMID:7929244, GO:0005737=GO_REF:0000052, GO:0005525=GO_REF:0000037} P55039 Developmentally-regulated GTP-binding protein 2 protein 20080818 {GO:0005739=IEA, GO:0007165=TAS, GO:0005737=IDA, GO:0005525=IEA} signal transduction cytoplasm, mitochondrion GTP binding Human DROSHA IntAct UniProtKB {GO:0005515=PMID:15574589, GO:0003725=GO_REF:0000002, GO:0010467=Reactome:REACT_71, GO:0016075=GO_REF:0000002, GO:0004525=GO_REF:0000003, GO:0042254=GO_REF:0000037, GO:0031054=GO_REF:0000019, GO:0003723=GO_REF:0000002, GO:0005730=GO_REF:0000039, GO:0005654=Reactome:REACT_12414, GO:0046872=GO_REF:0000037, GO:0010586=GO_REF:0000019} Q9NRR4 Ribonuclease 3 protein 20130415 {GO:0005515=IPI, GO:0003725=IEA, GO:0010467=TAS, GO:0016075=IEA, GO:0004525=IEA, GO:0042254=IEA, GO:0031054=IEA, GO:0003723=IEA, GO:0005730=IEA, GO:0005654=TAS, GO:0046872=IEA, GO:0010586=IEA} gene expression, miRNA metabolic process, pre-miRNA processing, rRNA catabolic process, ribosome biogenesis nucleolus, nucleoplasm RNA binding, double-stranded RNA binding, metal ion binding, protein binding, ribonuclease III activity Human UniProtKB:Q8WYQ5 DRP2 PINC UniProtKB {GO:0005737=GO_REF:0000037, GO:0005886=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0007417=PMID:8640231, GO:0005856=GO_REF:0000039} Q13474 Dystrophin-related protein 2 protein 20030904 {GO:0005737=IEA, GO:0005886=IEA, GO:0005509=IEA, GO:0008270=IEA, GO:0007417=TAS, GO:0005856=IEA} central nervous system development cytoplasm, cytoskeleton, plasma membrane calcium ion binding, zinc ion binding Human DSC1 PINC UniProtKB {GO:0030057=GO_REF:0000039, GO:0016020=PMID:7679953, GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0005921=PMID:7679953, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000002} Q08554 Desmocollin-1 protein 20030904 {GO:0030057=IEA, GO:0016020=TAS, GO:0005886=IEA, GO:0005509=IEA, GO:0005921=TAS, GO:0016021=IEA, GO:0007156=IEA} homophilic cell adhesion desmosome, gap junction, integral to membrane, membrane, plasma membrane calcium ion binding Human DSC2 BHF-UCL UniProtKB {GO:0030057=PMID:21062920, GO:0086069=PMID:22781308, GO:0005913=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0086091=PMID:22781308, GO:0007155=PMID:2037591, GO:0007156=GO_REF:0000002, GO:0086005=PMID:22781308} Q02487 Desmocollin-2 protein 20120928 {GO:0030057=IDA, GO:0086069=IMP, GO:0005913=IEA, GO:0005886=IEA, GO:0005509=IEA, GO:0016021=IEA, GO:0086091=IMP, GO:0007155=TAS, GO:0007156=IEA, GO:0086005=IMP} bundle of His cell to Purkinje myocyte communication, cell adhesion, homophilic cell adhesion, regulation of heart rate by cardiac conduction, regulation of ventricular cardiac muscle cell action potential cell-cell adherens junction, desmosome, integral to membrane, plasma membrane calcium ion binding Human DSC3 PINC UniProtKB {GO:0030057=GO_REF:0000039, GO:0005737=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0016020=PMID:7929347, GO:0005911=PMID:7929347, GO:0005509=GO_REF:0000002, GO:0005576=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007155=PMID:7929347, GO:0001701=GO_REF:0000019, GO:0007156=GO_REF:0000002} Q14574 Desmocollin-3 protein 20030904 {GO:0030057=IEA, GO:0005737=IEA, GO:0005886=IEA, GO:0016020=TAS, GO:0005911=TAS, GO:0005509=IEA, GO:0005576=IEA, GO:0016021=IEA, GO:0007155=TAS, GO:0001701=IEA, GO:0007156=IEA} cell adhesion, homophilic cell adhesion, in utero embryonic development cell-cell junction, cytoplasm, desmosome, extracellular region, integral to membrane, membrane, plasma membrane calcium ion binding Human DSCAM Reactome UniProtKB {GO:0005515=PMID:19196994, GO:0030424=GO_REF:0000024, GO:0005886=Reactome:REACT_25384, GO:0048842=PMID:18585357, GO:0005576=GO_REF:0000039, GO:0007399=PMID:9426258, GO:0070593=GO_REF:0000024, GO:0030426=GO_REF:0000024, GO:0048813=GO_REF:0000019, GO:0007162=GO_REF:0000024, GO:0016020=PMID:9426258, GO:0005887=PMID:9426258, GO:0007626=GO_REF:0000019, GO:0007155=GO_REF:0000037, GO:0060060=GO_REF:0000019, GO:0042327=PMID:19196994} O60469 Down syndrome cell adhesion molecule protein 20100105 {GO:0005515=IPI, GO:0030424=ISS, GO:0005886=TAS, GO:0048842=IDA, GO:0005576=IEA, GO:0007399=TAS, GO:0070593=ISS, GO:0030426=ISS, GO:0048813=IEA, GO:0007162=ISS, GO:0016020=TAS, GO:0005887=TAS, GO:0007626=IEA, GO:0007155=IEA, GO:0060060=IEA, GO:0042327=IDA} cell adhesion, dendrite morphogenesis, dendrite self-avoidance, locomotory behavior, negative regulation of cell adhesion, nervous system development, positive regulation of axon extension involved in axon guidance, positive regulation of phosphorylation, post-embryonic retina morphogenesis in camera-type eye axon, extracellular region, growth cone, integral to plasma membrane, membrane, plasma membrane protein binding Human DSCAML1 Reactome UniProtKB {GO:0009986=PMID:11453658, GO:0005886=Reactome:REACT_25036, GO:0001709=PMID:12051741, GO:0048704=PMID:12051741, GO:0007409=PMID:11453658, GO:0009953=PMID:12051741, GO:0007417=PMID:12051741, GO:0042803=PMID:11453658, GO:0070593=GO_REF:0000019, GO:0007162=GO_REF:0000019, GO:0007420=PMID:12051741, GO:0016021=GO_REF:0000037, GO:0007156=PMID:11453658} Q8TD84 Down syndrome cell adhesion molecule-like protein 1 protein 20100105 {GO:0009986=IDA, GO:0005886=TAS, GO:0001709=NAS, GO:0048704=IDA, GO:0007409=NAS, GO:0009953=NAS, GO:0007417=NAS, GO:0042803=IDA, GO:0070593=IEA, GO:0007162=IEA, GO:0007420=IDA, GO:0016021=IEA, GO:0007156=IDA} axonogenesis, brain development, cell fate determination, central nervous system development, dendrite self-avoidance, dorsal/ventral pattern formation, embryonic skeletal system morphogenesis, homophilic cell adhesion, negative regulation of cell adhesion cell surface, integral to membrane, plasma membrane protein homodimerization activity Human DSCC1 UniProtKB UniProtKB {GO:0005515=PMID:16682347, GO:0006260=GO_REF:0000037, GO:0034421=PMID:19907496, GO:0034088=PMID:19907496, GO:0005654=PMID:16682347, GO:0000785=PMID:19907496, GO:0003677=GO_REF:0000037, GO:0006275=PMID:19907496, GO:0000775=PMID:16682347} Q9BVC3 Sister chromatid cohesion protein DCC1 protein 20100924 {GO:0005515=IPI, GO:0006260=IEA, GO:0034421=IMP, GO:0034088=IMP, GO:0005654=IDA, GO:0000785=IDA, GO:0003677=IEA, GO:0006275=IMP, GO:0000775=IDA} DNA replication, maintenance of mitotic sister chromatid cohesion, post-translational protein acetylation, regulation of DNA replication chromatin, chromosome, centromeric region, nucleoplasm DNA binding, protein binding Human DSCR3 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0007034=GO_REF:0000002, GO:0005634=PMID:16780588, GO:0030904=GO_REF:0000002} O14972 Down syndrome critical region protein 3 protein 20070711 {GO:0003674=ND, GO:0008150=ND, GO:0007034=IEA, GO:0005634=IDA, GO:0030904=IEA} biological_process, vacuolar transport nucleus, retromer complex molecular_function Human DSE Reactome UniProtKB {GO:0030208=Reactome:REACT_120800, GO:0030206=GO_REF:0000041, GO:0005794=PMID:10679095, GO:0000139=Reactome:REACT_120814, GO:0005975=Reactome:REACT_474, GO:0005783=PMID:10679095, GO:0047757=PMID:16505484, GO:0044281=Reactome:REACT_111217, GO:0015012=GO_REF:0000041, GO:0016021=GO_REF:0000037, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121315} Q9UL01 Dermatan-sulfate epimerase protein 20130301 {GO:0030208=TAS, GO:0030206=IEA, GO:0005794=IDA, GO:0000139=TAS, GO:0005975=TAS, GO:0005783=IDA, GO:0047757=IDA, GO:0044281=TAS, GO:0015012=IEA, GO:0016021=IEA, GO:0030204=TAS, GO:0030203=TAS} carbohydrate metabolic process, chondroitin sulfate biosynthetic process, chondroitin sulfate metabolic process, dermatan sulfate biosynthetic process, glycosaminoglycan metabolic process, heparan sulfate proteoglycan biosynthetic process, small molecule metabolic process Golgi apparatus, Golgi membrane, endoplasmic reticulum, integral to membrane chondroitin-glucuronate 5-epimerase activity Human DSEL UniProtKB UniProtKB {GO:0008146=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0016853=GO_REF:0000037} Q8IZU8 Dermatan-sulfate epimerase-like protein protein 20130413 {GO:0008146=IEA, GO:0016021=IEA, GO:0016853=IEA} integral to membrane isomerase activity, sulfotransferase activity Human UniProtKB-KW:KW-0413 DSG1 BHF-UCL UniProtKB {GO:0030057=PMID:1711210, GO:0045295=PMID:7983064, GO:0005886=Reactome:REACT_11997, GO:0005509=PMID:1770008, GO:0060135=GO_REF:0000019, GO:0050821=PMID:7983064, GO:0006915=Reactome:REACT_578, GO:0016328=GO_REF:0000019, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_11997, GO:0016339=PMID:1770008, GO:0016324=GO_REF:0000019, GO:0016337=PMID:1711210, GO:0005911=PMID:7983064, GO:0015643=PMID:12582396, GO:0032570=GO_REF:0000019, GO:0007043=PMID:12485422, GO:0009898=PMID:7983064, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000002} Q02413 Desmoglein-1 protein 20100203 {GO:0030057=NAS, GO:0045295=IPI, GO:0005886=TAS, GO:0005509=NAS, GO:0060135=IEA, GO:0050821=IDA, GO:0006915=TAS, GO:0016328=IEA, GO:0006921=TAS, GO:0005829=TAS, GO:0016339=NAS, GO:0016324=IEA, GO:0016337=NAS, GO:0005911=IDA, GO:0015643=NAS, GO:0032570=IEA, GO:0007043=NAS, GO:0009898=IDA, GO:0016021=IEA, GO:0007156=IEA} apoptotic process, calcium-dependent cell-cell adhesion, cell-cell adhesion, cell-cell junction assembly, cellular component disassembly involved in execution phase of apoptosis, homophilic cell adhesion, maternal process involved in female pregnancy, protein stabilization, response to progesterone stimulus apical plasma membrane, cell-cell junction, cytosol, desmosome, integral to membrane, internal side of plasma membrane, lateral plasma membrane, plasma membrane calcium ion binding, gamma-catenin binding, toxic substance binding Human DSG2 BHF-UCL UniProtKB {GO:0030057=GO_REF:0000039, GO:0005886=GO_REF:0000052, GO:0005509=GO_REF:0000002, GO:0097194=PMID:17559062, GO:0006915=Reactome:REACT_578, GO:0086091=PMID:22781308, GO:0006921=Reactome:REACT_995, GO:0086069=PMID:22781308, GO:0005911=PMID:8143788, GO:0016021=GO_REF:0000037, GO:0007155=PMID:17559062, GO:0007156=GO_REF:0000002, GO:0086005=PMID:22781308} Q14126 Desmoglein-2 protein 20120928 {GO:0030057=IEA, GO:0005886=IDA, GO:0005509=IEA, GO:0097194=IDA, GO:0006915=TAS, GO:0086091=IMP, GO:0006921=TAS, GO:0086069=IMP, GO:0005911=TAS, GO:0016021=IEA, GO:0007155=IDA, GO:0007156=IEA, GO:0086005=IMP} apoptotic process, bundle of His cell to Purkinje myocyte communication, cell adhesion, cellular component disassembly involved in execution phase of apoptosis, execution phase of apoptosis, homophilic cell adhesion, regulation of heart rate by cardiac conduction, regulation of ventricular cardiac muscle cell action potential cell-cell junction, desmosome, integral to membrane, plasma membrane calcium ion binding Human DSG3 Reactome UniProtKB {GO:0030057=GO_REF:0000039, GO:0005886=Reactome:REACT_12082, GO:0005509=GO_REF:0000002, GO:0006915=Reactome:REACT_578, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000002, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_12082} P32926 Desmoglein-3 protein 20130301 {GO:0030057=IEA, GO:0005886=TAS, GO:0005509=IEA, GO:0006915=TAS, GO:0016021=IEA, GO:0007156=IEA, GO:0006921=TAS, GO:0005829=TAS} apoptotic process, cellular component disassembly involved in execution phase of apoptosis, homophilic cell adhesion cytosol, desmosome, integral to membrane, plasma membrane calcium ion binding Human DSN1 HPA UniProtKB {GO:0005515=PMID:15502821, GO:0000236=Reactome:REACT_682, GO:0005737=GO_REF:0000052, GO:0007059=GO_REF:0000037, GO:0000087=Reactome:REACT_910, GO:0005634=GO_REF:0000052, GO:0000444=PMID:16585270, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0005829=Reactome:REACT_150414, GO:0051301=GO_REF:0000037} Q9H410 Kinetochore-associated protein DSN1 homolog protein 20080205 {GO:0005515=IPI, GO:0000236=TAS, GO:0005737=IDA, GO:0007059=IEA, GO:0000087=TAS, GO:0005634=IDA, GO:0000444=IDA, GO:0000278=TAS, GO:0000090=TAS, GO:0005829=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, cell division, chromosome segregation, mitotic anaphase, mitotic cell cycle, mitotic prometaphase MIS12/MIND type complex, cytoplasm, cytosol, nucleus protein binding Human DSP BHF-UCL UniProtKB {GO:0005882=PMID:16917092, GO:0005515=PMID:16917092, GO:0030057=GO_REF:0000039, GO:0045109=PMID:16917092, GO:0005886=PMID:16917092, GO:0086091=PMID:22781308, GO:0001533=PMID:10908733, GO:0006921=Reactome:REACT_995, GO:0005739=GO_REF:0000019, GO:0016323=GO_REF:0000019, GO:0016337=GO_REF:0000019, GO:0086069=PMID:22781308, GO:0003223=PMID:16917092, GO:0097110=PMID:10852826, GO:0005080=PMID:18474624, GO:0030674=PMID:10908733, GO:0086005=PMID:22781308, GO:0006915=Reactome:REACT_578, GO:0018149=PMID:10908733, GO:0002934=PMID:16917092, GO:0008544=PMID:9887343, GO:0030216=PMID:10908733, GO:0005198=PMID:10908733, GO:0071896=PMID:16917092, GO:0005200=PMID:9887343, GO:0043588=GO_REF:0000019, GO:0034332=GO_REF:0000019} P15924 Desmoplakin protein 20120625 {GO:0005882=ISS, GO:0005515=IPI, GO:0030057=IEA, GO:0045109=ISS, GO:0005886=IDA, GO:0086091=IMP, GO:0001533=IDA, GO:0006921=TAS, GO:0005739=IEA, GO:0016323=IEA, GO:0016337=IEA, GO:0086069=IMP, GO:0003223=ISS, GO:0097110=IPI, GO:0005080=IPI, GO:0030674=IDA, GO:0086005=IMP, GO:0006915=TAS, GO:0018149=IDA, GO:0002934=ISS, GO:0008544=TAS, GO:0030216=IDA, GO:0005198=IDA, GO:0071896=ISS, GO:0005200=TAS, GO:0043588=IEA, GO:0034332=IEA} adherens junction organization, apoptotic process, bundle of His cell to Purkinje myocyte communication, cell-cell adhesion, cellular component disassembly involved in execution phase of apoptosis, desmosome organization, epidermis development, intermediate filament organization, keratinocyte differentiation, peptide cross-linking, protein localization to adherens junction, regulation of heart rate by cardiac conduction, regulation of ventricular cardiac muscle cell action potential, skin development, ventricular compact myocardium morphogenesis basolateral plasma membrane, cornified envelope, desmosome, intermediate filament, mitochondrion, plasma membrane protein binding, protein binding, bridging, protein kinase C binding, scaffold protein binding, structural constituent of cytoskeleton, structural molecule activity colocalizes_with Human UniProtKB:E9Q557 DSPP PINC UniProtKB {GO:0001501=PMID:8995371, GO:0001503=PMID:9879917, GO:0071460=GO_REF:0000019, GO:0005518=PMID:9879917, GO:0005509=PMID:9879917, GO:0005578=GO_REF:0000039, GO:0007275=PMID:8995371, GO:0031214=GO_REF:0000037, GO:0005201=PMID:8995371} Q9NZW4 Dentin sialophosphoprotein protein 20050308 {GO:0001501=TAS, GO:0001503=TAS, GO:0071460=IEA, GO:0005518=TAS, GO:0005509=TAS, GO:0005578=IEA, GO:0007275=TAS, GO:0031214=IEA, GO:0005201=TAS} biomineral tissue development, cellular response to cell-matrix adhesion, multicellular organismal development, ossification, skeletal system development proteinaceous extracellular matrix calcium ion binding, collagen binding, extracellular matrix structural constituent Human DST UniProtKB UniProtKB {GO:0005515=PMID:19632184, GO:0005882=GO_REF:0000037, GO:0030424=GO_REF:0000039, GO:0030056=PMID:11375975, GO:0008090=GO_REF:0000019, GO:0030018=GO_REF:0000039, GO:0045104=PMID:11375975, GO:0042626=GO_REF:0000002, GO:0035371=PMID:19632184, GO:0005634=GO_REF:0000052, GO:0031122=GO_REF:0000019, GO:0030011=PMID:19403692, GO:0007409=GO_REF:0000019, GO:0005635=GO_REF:0000039, GO:0015629=GO_REF:0000019, GO:0005829=Reactome:REACT_150217, GO:0005737=GO_REF:0000052, GO:0009925=PMID:11375975, GO:0051010=PMID:19632184, GO:0030198=Reactome:REACT_118779, GO:0048870=PMID:19403692, GO:0007010=PMID:19403692, GO:0015630=GO_REF:0000052, GO:0007050=GO_REF:0000002, GO:0007155=GO_REF:0000037, GO:0005856=GO_REF:0000002, GO:0031252=PMID:19403692, GO:0005938=GO_REF:0000039, GO:0060053=GO_REF:0000019, GO:0031110=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0009611=PMID:19403692, GO:0003779=GO_REF:0000038, GO:0008022=PMID:11375975, GO:0005524=GO_REF:0000002, GO:0005604=PMID:2461961, GO:0005178=PMID:11375975, GO:0007229=PMID:11375975, GO:0005789=GO_REF:0000039, GO:0016023=PMID:14581450, GO:0016021=GO_REF:0000037, GO:0031673=GO_REF:0000039} Q5T0V7 Dystonin protein 20130413 {GO:0005515=IPI, GO:0005882=IEA, GO:0030424=IEA, GO:0030056=TAS, GO:0008090=IEA, GO:0030018=IEA, GO:0045104=NAS, GO:0042626=IEA, GO:0035371=IDA, GO:0005634=IDA, GO:0031122=IEA, GO:0030011=IMP, GO:0007409=IEA, GO:0005635=IEA, GO:0015629=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0009925=NAS, GO:0051010=IDA, GO:0030198=TAS, GO:0048870=IMP, GO:0007010=IMP, GO:0015630=IDA, GO:0007050=IEA, GO:0007155=IEA, GO:0005856=IEA, GO:0031252=IDA, GO:0005938=IEA, GO:0060053=IEA, GO:0031110=IEA, GO:0005509=IEA, GO:0009611=IDA, GO:0003779=IEA, GO:0008022=IPI, GO:0005524=IEA, GO:0005604=TAS, GO:0005178=IPI, GO:0007229=NAS, GO:0005789=IEA, GO:0016023=IDA, GO:0016021=IEA, GO:0031673=IEA} axonogenesis, cell adhesion, cell cycle arrest, cell motility, cytoplasmic microtubule organization, cytoskeleton organization, extracellular matrix organization, integrin-mediated signaling pathway, intermediate filament cytoskeleton organization, maintenance of cell polarity, regulation of microtubule polymerization or depolymerization, response to wounding, retrograde axon cargo transport H zone, Z disc, actin cytoskeleton, axon, basal plasma membrane, basement membrane, cell cortex, cell leading edge, cytoplasm, cytoplasmic membrane-bounded vesicle, cytoskeleton, cytosol, endoplasmic reticulum membrane, hemidesmosome, integral to membrane, intermediate filament, microtubule cytoskeleton, microtubule plus end, neurofilament cytoskeleton, nuclear envelope, nucleus ATP binding, ATPase activity, coupled to transmembrane movement of substances, actin binding, calcium ion binding, integrin binding, microtubule plus-end binding, protein C-terminus binding, protein binding Human UniProtKB-KW:KW-0009 DSTN PINC UniProtKB {GO:0051014=PMID:8399167, GO:0000910=GO_REF:0000019, GO:0008154=PMID:8399167, GO:0030836=GO_REF:0000019, GO:0006928=GO_REF:0000019, GO:0030042=GO_REF:0000002, GO:0003779=GO_REF:0000037, GO:0030864=GO_REF:0000019, GO:0015629=PMID:8399167} P60981 Destrin protein 20061109 {GO:0051014=TAS, GO:0000910=IEA, GO:0008154=TAS, GO:0030836=IEA, GO:0006928=IEA, GO:0030042=IEA, GO:0003779=IEA, GO:0030864=IEA, GO:0015629=TAS} actin filament depolymerization, actin filament severing, actin polymerization or depolymerization, cellular component movement, cytokinesis, positive regulation of actin filament depolymerization actin cytoskeleton, cortical actin cytoskeleton actin binding Human DSTYK HPA UniProtKB {GO:0005737=GO_REF:0000039, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0004712=GO_REF:0000003, GO:0045111=GO_REF:0000052, GO:0004713=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q6XUX3 Dual serine/threonine and tyrosine protein kinase protein 20120912 {GO:0005737=IEA, GO:0004672=IEA, GO:0004674=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0004712=IEA, GO:0045111=IDA, GO:0004713=IEA, GO:0005524=IEA} cytoplasm, intermediate filament cytoskeleton, nucleolus, nucleus ATP binding, protein kinase activity, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity, protein tyrosine kinase activity Human DTD1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0016788=GO_REF:0000002, GO:0019478=GO_REF:0000002} Q8TEA8 D-tyrosyl-tRNA(Tyr) deacylase 1 protein 20101115 {GO:0005737=IDA, GO:0005730=IDA, GO:0016788=IEA, GO:0019478=IEA} D-amino acid catabolic process cytoplasm, nucleolus hydrolase activity, acting on ester bonds Human DTL HPA UniProtKB {GO:0005515=PMID:17041588, GO:0000209=PMID:18794347, GO:0006511=PMID:18794347, GO:0005813=PMID:17106265, GO:0031965=GO_REF:0000039, GO:0004842=PMID:20129063, GO:0006513=PMID:20129063, GO:0031572=PMID:17085480, GO:0005634=GO_REF:0000052, GO:0019985=PMID:20129063, GO:0006974=PMID:20129063, GO:0006260=GO_REF:0000037, GO:0005737=GO_REF:0000037, GO:0051726=PMID:17085480, GO:0031465=PMID:18794347, GO:0031464=PMID:18794347, GO:0009411=PMID:18794347} Q9NZJ0 Denticleless protein homolog protein 20101115 {GO:0005515=IPI, GO:0000209=IDA, GO:0006511=IDA, GO:0005813=IDA, GO:0031965=IEA, GO:0004842=IDA, GO:0006513=IDA, GO:0031572=IMP, GO:0005634=IDA, GO:0019985=IDA, GO:0006974=IDA, GO:0006260=IEA, GO:0005737=IEA, GO:0051726=IMP, GO:0031465=IDA, GO:0031464=IDA, GO:0009411=IDA} DNA replication, G2 DNA damage checkpoint, protein monoubiquitination, protein polyubiquitination, regulation of cell cycle, response to DNA damage stimulus, response to UV, translesion synthesis, ubiquitin-dependent protein catabolic process Cul4A-RING ubiquitin ligase complex, Cul4B-RING ubiquitin ligase complex, centrosome, cytoplasm, nuclear membrane, nucleus protein binding, ubiquitin-protein ligase activity Human DTNA PINC UniProtKB {GO:0005515=PMID:11353857, GO:0007165=PMID:10767327, GO:0043234=PMID:18468998, GO:0005737=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0006941=PMID:10767327, GO:0007268=PMID:8845841, GO:0045202=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0007274=PMID:9119373} Q9Y4J8 Dystrobrevin alpha protein 20030904 {GO:0005515=IPI, GO:0007165=TAS, GO:0043234=IDA, GO:0005737=IEA, GO:0030054=IEA, GO:0005886=IEA, GO:0005509=IEA, GO:0006941=TAS, GO:0007268=TAS, GO:0045202=IEA, GO:0008270=IEA, GO:0007274=TAS} neuromuscular synaptic transmission, signal transduction, striated muscle contraction, synaptic transmission cell junction, cytoplasm, plasma membrane, protein complex, synapse calcium ion binding, protein binding, zinc ion binding Human DTNB UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0045202=GO_REF:0000019, GO:0008270=GO_REF:0000002} O60941 Dystrobrevin beta protein 20130413 {GO:0005737=IEA, GO:0005509=IEA, GO:0045202=IEA, GO:0008270=IEA} cytoplasm, synapse calcium ion binding, zinc ion binding Human UniProtKB-SubCell:SL-0086 DTNBP1 Reactome UniProtKB {GO:0005515=PMID:20921223, GO:0043005=PMID:16980328, GO:0033162=GO_REF:0000039, GO:0030424=GO_REF:0000024, GO:0048490=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0032438=PMID:22203680, GO:0005634=GO_REF:0000024, GO:0014059=GO_REF:0000024, GO:0031175=PMID:16980328, GO:0005829=Reactome:REACT_19390, GO:0030426=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0043197=GO_REF:0000024, GO:0045211=GO_REF:0000039, GO:0030672=GO_REF:0000024, GO:0031532=GO_REF:0000024, GO:0006892=Reactome:REACT_11235, GO:0014069=PMID:16980328, GO:0042383=GO_REF:0000024, GO:0033267=GO_REF:0000024, GO:0010628=GO_REF:0000024, GO:0016528=GO_REF:0000019, GO:0031083=PMID:22203680, GO:0007596=GO_REF:0000019, GO:0060159=GO_REF:0000024, GO:0048812=GO_REF:0000024, GO:0005789=GO_REF:0000024, GO:0060155=GO_REF:0000019, GO:0008089=GO_REF:0000024, GO:0001956=GO_REF:0000024, GO:0016044=Reactome:REACT_11123, GO:0010008=GO_REF:0000039} Q96EV8 Dysbindin protein 20090819 {GO:0005515=IPI, GO:0043005=IDA, GO:0033162=IEA, GO:0030424=ISS, GO:0048490=ISS, GO:0030054=IEA, GO:0032438=NAS, GO:0005634=ISS, GO:0014059=ISS, GO:0031175=IDA, GO:0005829=TAS, GO:0030426=ISS, GO:0005737=ISS, GO:0043197=ISS, GO:0045211=IEA, GO:0030672=ISS, GO:0031532=ISS, GO:0006892=TAS, GO:0014069=IDA, GO:0042383=ISS, GO:0033267=ISS, GO:0010628=ISS, GO:0016528=IEA, GO:0031083=IDA, GO:0007596=IEA, GO:0060159=ISS, GO:0048812=ISS, GO:0005789=ISS, GO:0060155=IEA, GO:0008089=ISS, GO:0001956=ISS, GO:0016044=TAS, GO:0010008=IEA} actin cytoskeleton reorganization, anterograde axon cargo transport, anterograde synaptic vesicle transport, blood coagulation, cellular membrane organization, melanosome organization, neuron projection development, neuron projection morphogenesis, platelet dense granule organization, positive regulation of gene expression, positive regulation of neurotransmitter secretion, post-Golgi vesicle-mediated transport, regulation of dopamine receptor signaling pathway, regulation of dopamine secretion BLOC-1 complex, axon, axon part, cell junction, cytoplasm, cytosol, dendritic spine, endoplasmic reticulum membrane, endosome membrane, growth cone, melanosome membrane, neuron projection, nucleus, postsynaptic density, postsynaptic membrane, sarcolemma, sarcoplasm, synaptic vesicle membrane protein binding Human DTWD1 null null {} null null null null {} null null null DTWD2 null null {} null null null null {} null null null DTX1 Reactome UniProtKB {GO:0005515=PMID:7671825, GO:0017124=GO_REF:0000037, GO:0016567=GO_REF:0000041, GO:0006366=PMID:9590294, GO:0016874=GO_REF:0000037, GO:0003713=PMID:9590294, GO:0005112=PMID:11564735, GO:0005634=GO_REF:0000039, GO:0006351=PMID:11564735, GO:0005829=Reactome:REACT_118743, GO:0005737=PMID:9590294, GO:0007219=Reactome:REACT_118859, GO:0045665=PMID:11564735, GO:0010001=GO_REF:0000019, GO:0045581=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0007166=PMID:9590294, GO:0008593=PMID:11564735, GO:0031625=PMID:17028573} Q86Y01 E3 ubiquitin-protein ligase DTX1 protein 20130301 {GO:0005515=IPI, GO:0017124=IEA, GO:0016567=IEA, GO:0006366=TAS, GO:0016874=IEA, GO:0003713=TAS, GO:0005112=IDA, GO:0005634=IEA, GO:0006351=NAS, GO:0005829=TAS, GO:0005737=TAS, GO:0007219=TAS, GO:0045665=IGI, GO:0010001=IEA, GO:0045581=IEA, GO:0008270=IEA, GO:0007166=TAS, GO:0008593=IGI, GO:0031625=IPI} Notch signaling pathway, cell surface receptor signaling pathway, glial cell differentiation, negative regulation of T cell differentiation, negative regulation of neuron differentiation, protein ubiquitination, regulation of Notch signaling pathway, transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, cytosol, nucleus Notch binding, SH3 domain binding, ligase activity, protein binding, transcription coactivator activity, ubiquitin protein ligase binding, zinc ion binding Human DTX2 HPA UniProtKB {GO:0005515=PMID:19549727, GO:0005737=GO_REF:0000039, GO:0031965=GO_REF:0000052, GO:0016567=GO_REF:0000041, GO:0007219=GO_REF:0000019, GO:0016874=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002} Q86UW9 Probable E3 ubiquitin-protein ligase DTX2 protein 20120912 {GO:0005515=IPI, GO:0005737=IEA, GO:0031965=IDA, GO:0016567=IEA, GO:0007219=IEA, GO:0016874=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA} Notch signaling pathway, protein ubiquitination cytoplasm, nuclear membrane, nucleolus, nucleus ligase activity, protein binding, zinc ion binding Human DTX3 UniPathway UniProtKB {GO:0005737=GO_REF:0000039, GO:0016567=GO_REF:0000041, GO:0007219=GO_REF:0000019, GO:0016874=GO_REF:0000037, GO:0008270=GO_REF:0000002} Q8N9I9 Probable E3 ubiquitin-protein ligase DTX3 protein 20130413 {GO:0005737=IEA, GO:0016567=IEA, GO:0007219=IEA, GO:0016874=IEA, GO:0008270=IEA} Notch signaling pathway, protein ubiquitination cytoplasm ligase activity, zinc ion binding Human UniPathway:UPA00143 DTX3L UniProtKB UniProtKB {GO:0005515=PMID:23230272, GO:0042393=PMID:19818714, GO:0005737=PMID:16809771, GO:0004842=PMID:23230272, GO:0005634=PMID:16809771, GO:0008270=GO_REF:0000002, GO:0010390=PMID:19818714, GO:0006974=PMID:19818714, GO:0006302=PMID:23230272} Q8TDB6 E3 ubiquitin-protein ligase DTX3L protein 20130409 {GO:0005515=IPI, GO:0042393=IDA, GO:0005737=IDA, GO:0004842=IMP, GO:0005634=IDA, GO:0008270=IEA, GO:0010390=IDA, GO:0006974=IMP, GO:0006302=IMP} double-strand break repair, histone monoubiquitination, response to DNA damage stimulus cytoplasm, nucleus histone binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q8IXQ6 DTX4 UniPathway UniProtKB {GO:0005737=GO_REF:0000039, GO:0016567=GO_REF:0000041, GO:0007219=GO_REF:0000037, GO:0016874=GO_REF:0000037, GO:0008270=GO_REF:0000002} Q9Y2E6 E3 ubiquitin-protein ligase DTX4 protein 20130413 {GO:0005737=IEA, GO:0016567=IEA, GO:0007219=IEA, GO:0016874=IEA, GO:0008270=IEA} Notch signaling pathway, protein ubiquitination cytoplasm ligase activity, zinc ion binding Human UniPathway:UPA00143 DTYMK GOC UniProtKB {GO:0043627=GO_REF:0000019, GO:0015949=Reactome:REACT_21330, GO:0008283=PMID:8024690, GO:0050145=Reactome:REACT_636, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0006233=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0006235=GO_REF:0000041, GO:0004798=PMID:8845311, GO:0005829=Reactome:REACT_636, GO:0046940=Reactome:REACT_636, GO:0005758=GO_REF:0000019, GO:0007049=PMID:8024690, GO:0071363=GO_REF:0000019, GO:0005759=GO_REF:0000019, GO:0045445=GO_REF:0000019, GO:0046686=GO_REF:0000019} P23919 Thymidylate kinase protein 20130413 {GO:0043627=IEA, GO:0015949=TAS, GO:0008283=TAS, GO:0050145=EXP, GO:0055086=TAS, GO:0044281=TAS, GO:0006233=IEA, GO:0005524=IEA, GO:0006235=IEA, GO:0004798=IDA, GO:0005829=TAS, GO:0046940=EXP, GO:0005758=IEA, GO:0007049=TAS, GO:0071363=IEA, GO:0005759=IEA, GO:0045445=IEA, GO:0046686=IEA} cell cycle, cell proliferation, cellular response to growth factor stimulus, dTDP biosynthetic process, dTTP biosynthetic process, myoblast differentiation, nucleobase-containing small molecule interconversion, nucleobase-containing small molecule metabolic process, nucleoside monophosphate phosphorylation, response to cadmium ion, response to estrogen stimulus, small molecule metabolic process cytosol, mitochondrial intermembrane space, mitochondrial matrix ATP binding, nucleoside phosphate kinase activity, thymidylate kinase activity Human DUOX1 UniProtKB UniProtKB {GO:0042554=PMID:10806195, GO:0050661=PMID:10806195, GO:0042335=PMID:11514595, GO:0005886=GO_REF:0000019, GO:0019221=PMID:16111680, GO:0072593=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0050665=PMID:10806195, GO:0051591=GO_REF:0000024, GO:0016324=PMID:10806195, GO:0004601=GO_REF:0000037, GO:0042446=GO_REF:0000037, GO:0016174=PMID:10806195, GO:0006590=GO_REF:0000041, GO:0016021=GO_REF:0000037, GO:0042744=GO_REF:0000037, GO:0006979=GO_REF:0000002, GO:0055114=PMID:10601291, GO:0020037=GO_REF:0000002} Q9NRD9 Dual oxidase 1 protein 20060427 {GO:0042554=NAS, GO:0050661=NAS, GO:0042335=IMP, GO:0005886=IEA, GO:0019221=IDA, GO:0072593=IEA, GO:0005509=IEA, GO:0050665=NAS, GO:0051591=ISS, GO:0016324=NAS, GO:0004601=IEA, GO:0042446=IEA, GO:0016174=NAS, GO:0006590=IEA, GO:0016021=IEA, GO:0042744=IEA, GO:0006979=IEA, GO:0055114=TAS, GO:0020037=IEA} cuticle development, cytokine-mediated signaling pathway, hormone biosynthetic process, hydrogen peroxide biosynthetic process, hydrogen peroxide catabolic process, oxidation-reduction process, reactive oxygen species metabolic process, response to cAMP, response to oxidative stress, superoxide anion generation, thyroid hormone generation apical plasma membrane, integral to membrane, plasma membrane NAD(P)H oxidase activity, NADP binding, calcium ion binding, heme binding, peroxidase activity Human DUOX2 UniProtKB UniProtKB {GO:0048839=GO_REF:0000019, GO:0042335=GO_REF:0000024, GO:0005509=PMID:15972824, GO:0019221=PMID:16111680, GO:0030282=GO_REF:0000019, GO:0030878=GO_REF:0000019, GO:0009615=PMID:16111680, GO:0048855=GO_REF:0000019, GO:0051591=GO_REF:0000024, GO:0009566=GO_REF:0000019, GO:0016324=GO_REF:0000039, GO:0004601=GO_REF:0000037, GO:0035264=GO_REF:0000019, GO:0042446=GO_REF:0000037, GO:0016174=PMID:15972824, GO:0006590=GO_REF:0000041, GO:0016021=GO_REF:0000037, GO:0042744=GO_REF:0000037, GO:0055114=PMID:10601291, GO:0020037=GO_REF:0000002} Q9NRD8 Dual oxidase 2 protein 20060123 {GO:0048839=IEA, GO:0042335=ISS, GO:0005509=IDA, GO:0019221=IDA, GO:0030282=IEA, GO:0030878=IEA, GO:0009615=IDA, GO:0048855=IEA, GO:0051591=ISS, GO:0009566=IEA, GO:0016324=IEA, GO:0004601=IEA, GO:0035264=IEA, GO:0042446=IEA, GO:0016174=IDA, GO:0006590=IEA, GO:0016021=IEA, GO:0042744=IEA, GO:0055114=TAS, GO:0020037=IEA} adenohypophysis morphogenesis, bone mineralization, cuticle development, cytokine-mediated signaling pathway, fertilization, hormone biosynthetic process, hydrogen peroxide catabolic process, inner ear development, multicellular organism growth, oxidation-reduction process, response to cAMP, response to virus, thyroid gland development, thyroid hormone generation apical plasma membrane, integral to membrane NAD(P)H oxidase activity, calcium ion binding, heme binding, peroxidase activity Human UniProtKB:Q9NRD9 DUPD1 RefGenome UniProtKB {GO:0005737=GO_REF:0000039, GO:0006470=GO_REF:0000033, GO:0008138=GO_REF:0000033, GO:0004725=GO_REF:0000003} Q68J44 Dual specificity phosphatase DUPD1 protein 20110117 {GO:0005737=IEA, GO:0006470=IBA, GO:0008138=IBA, GO:0004725=IEA} protein dephosphorylation cytoplasm protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human PANTHER:PTN000016642 DUS2L HPA UniProtKB {GO:0005739=GO_REF:0000019, GO:0003725=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0005783=GO_REF:0000039, GO:0050660=GO_REF:0000002, GO:0017150=GO_REF:0000002} Q9NX74 "tRNA-dihydrouridine(20) synthase ""NAD(P)+""-like" protein 20111111 {GO:0005739=IEA, GO:0003725=IEA, GO:0005737=IDA, GO:0005783=IEA, GO:0050660=IEA, GO:0017150=IEA} cytoplasm, endoplasmic reticulum, mitochondrion double-stranded RNA binding, flavin adenine dinucleotide binding, tRNA dihydrouridine synthase activity Human DUS3L InterPro UniProtKB {GO:0050660=GO_REF:0000002, GO:0017150=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q96G46 "tRNA-dihydrouridine(47) synthase ""NAD(P)(+)""-like" protein 20130413 {GO:0050660=IEA, GO:0017150=IEA, GO:0008270=IEA, GO:0003676=IEA} flavin adenine dinucleotide binding, nucleic acid binding, tRNA dihydrouridine synthase activity, zinc ion binding Human InterPro:IPR001269|InterPro:IPR018517 DUS4L InterPro UniProtKB {GO:0050660=GO_REF:0000002, GO:0017150=GO_REF:0000002} O95620 "tRNA-dihydrouridine(20a/20b) synthase ""NAD(P)+""-like" protein 20130413 {GO:0050660=IEA, GO:0017150=IEA} flavin adenine dinucleotide binding, tRNA dihydrouridine synthase activity Human InterPro:IPR001269|InterPro:IPR018517 DUSP1 IntAct UniProtKB {GO:0005515=PMID:16286470, GO:0042542=GO_REF:0000019, GO:0001706=GO_REF:0000033, GO:0043065=GO_REF:0000019, GO:0008330=GO_REF:0000019, GO:0042981=GO_REF:0000033, GO:0051384=GO_REF:0000019, GO:0033574=GO_REF:0000019, GO:0051591=GO_REF:0000019, GO:0032870=GO_REF:0000019, GO:0000188=GO_REF:0000033, GO:0035556=GO_REF:0000019, GO:0051592=GO_REF:0000019, GO:0007049=GO_REF:0000037, GO:0006470=GO_REF:0000033, GO:0005654=GO_REF:0000033, GO:0009416=GO_REF:0000019, GO:0032526=GO_REF:0000019, GO:0006979=PMID:1406996, GO:0032355=GO_REF:0000019, GO:0017017=GO_REF:0000033, GO:0004726=PMID:1406996} P28562 Dual specificity protein phosphatase 1 protein 20130415 {GO:0005515=IPI, GO:0042542=IEA, GO:0001706=IBA, GO:0043065=IEA, GO:0008330=IEA, GO:0042981=IBA, GO:0051384=IEA, GO:0033574=IEA, GO:0051591=IEA, GO:0032870=IEA, GO:0000188=IBA, GO:0035556=IEA, GO:0051592=IEA, GO:0007049=IEA, GO:0006470=IBA, GO:0005654=IBA, GO:0009416=IEA, GO:0032526=IEA, GO:0006979=TAS, GO:0032355=IEA, GO:0017017=IBA, GO:0004726=TAS} cell cycle, cellular response to hormone stimulus, endoderm formation, inactivation of MAPK activity, intracellular signal transduction, positive regulation of apoptotic process, protein dephosphorylation, regulation of apoptotic process, response to cAMP, response to calcium ion, response to estradiol stimulus, response to glucocorticoid stimulus, response to hydrogen peroxide, response to light stimulus, response to oxidative stress, response to retinoic acid, response to testosterone stimulus nucleoplasm MAP kinase tyrosine/serine/threonine phosphatase activity, non-membrane spanning protein tyrosine phosphatase activity, protein binding, protein tyrosine/threonine phosphatase activity Human UniProtKB:Q13309 DUSP10 HPA UniProtKB {GO:0033549=PMID:22375048, GO:0005794=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0007254=PMID:10391943, GO:0006950=PMID:10391943, GO:0005634=GO_REF:0000052, GO:0060266=GO_REF:0000019, GO:0032873=GO_REF:0000033, GO:0000188=PMID:22375048, GO:0002819=GO_REF:0000019, GO:0016791=PMID:16806267, GO:0005737=PMID:10391943, GO:0006470=PMID:22375048, GO:0046329=GO_REF:0000033, GO:0032496=GO_REF:0000019, GO:0004721=PMID:10391943, GO:0043508=GO_REF:0000033, GO:0004725=GO_REF:0000003, GO:0017017=GO_REF:0000033} Q9Y6W6 Dual specificity protein phosphatase 10 protein 20101115 {GO:0033549=IDA, GO:0005794=IDA, GO:0005730=IDA, GO:0007254=TAS, GO:0006950=TAS, GO:0005634=IDA, GO:0060266=IEA, GO:0032873=IBA, GO:0000188=IDA, GO:0002819=IEA, GO:0016791=IDA, GO:0005737=TAS, GO:0006470=IDA, GO:0046329=IBA, GO:0032496=IEA, GO:0004721=TAS, GO:0043508=IBA, GO:0004725=IEA, GO:0017017=IBA} JNK cascade, inactivation of MAPK activity, negative regulation of JNK cascade, negative regulation of JUN kinase activity, negative regulation of respiratory burst involved in inflammatory response, negative regulation of stress-activated MAPK cascade, protein dephosphorylation, regulation of adaptive immune response, response to lipopolysaccharide, response to stress Golgi apparatus, cytoplasm, nucleolus, nucleus MAP kinase phosphatase activity, MAP kinase tyrosine/serine/threonine phosphatase activity, phosphatase activity, phosphoprotein phosphatase activity, protein tyrosine phosphatase activity Human DUSP11 GOC UniProtKB {GO:0006396=PMID:9685386, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008138=GO_REF:0000002, GO:0035335=PMID:9685386, GO:0004725=GO_REF:0000002} O75319 RNA/RNP complex-1-interacting phosphatase protein 20130413 {GO:0006396=TAS, GO:0003723=IEA, GO:0005634=IEA, GO:0008138=IEA, GO:0035335=TAS, GO:0004725=IEA} RNA processing, peptidyl-tyrosine dephosphorylation nucleus RNA binding, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human DUSP12 GOC UniProtKB {GO:0005737=GO_REF:0000033, GO:0006470=GO_REF:0000033, GO:0007254=GO_REF:0000033, GO:0005634=GO_REF:0000052, GO:0033133=GO_REF:0000033, GO:0008270=GO_REF:0000002, GO:0008138=GO_REF:0000033, GO:0019900=GO_REF:0000019, GO:0035335=PMID:10446167, GO:0006464=PMID:10446167, GO:0004725=GO_REF:0000003} Q9UNI6 Dual specificity protein phosphatase 12 protein 20130413 {GO:0005737=IBA, GO:0006470=IBA, GO:0007254=IRD, GO:0005634=IDA, GO:0033133=IBA, GO:0008270=IEA, GO:0008138=IBA, GO:0019900=IEA, GO:0035335=TAS, GO:0006464=TAS, GO:0004725=IEA} JNK cascade, cellular protein modification process, peptidyl-tyrosine dephosphorylation, positive regulation of glucokinase activity, protein dephosphorylation cytoplasm, nucleus kinase binding, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity, zinc ion binding Human DUSP13 PINC UniProtKB {GO:0005737=PMID:15252030, GO:0007126=PMID:10585869, GO:0006470=GO_REF:0000033, GO:0007283=PMID:10585869, GO:0008138=GO_REF:0000033, GO:0004725=GO_REF:0000003} Q9UII6 Dual specificity protein phosphatase 13 protein 20030904 {GO:0005737=IDA, GO:0007126=TAS, GO:0006470=IBA, GO:0007283=TAS, GO:0008138=IBA, GO:0004725=IEA} meiosis, protein dephosphorylation, spermatogenesis cytoplasm protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human DUSP14 RefGenome UniProtKB {GO:0008138=GO_REF:0000033, GO:0035335=GO_REF:0000033, GO:0004725=GO_REF:0000003, GO:0017017=GO_REF:0000002} O95147 Dual specificity protein phosphatase 14 protein 20110118 {GO:0008138=IBA, GO:0035335=IBA, GO:0004725=IEA, GO:0017017=IEA} peptidyl-tyrosine dephosphorylation MAP kinase tyrosine/serine/threonine phosphatase activity, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human PANTHER:PTN000017471 DUSP15 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0005737=GO_REF:0000039, GO:0006470=GO_REF:0000033, GO:0005886=GO_REF:0000039, GO:0008138=GO_REF:0000033, GO:0004725=GO_REF:0000003} Q9H1R2 Dual specificity protein phosphatase 15 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0006470=IBA, GO:0005886=IEA, GO:0008138=IBA, GO:0004725=IEA} protein dephosphorylation cytoplasm, plasma membrane protein binding, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human UniProtKB:P19174 DUSP16 UniProtKB UniProtKB {GO:0045209=PMID:11489891, GO:0000188=PMID:11489891, GO:0016791=GO_REF:0000019, GO:0005737=PMID:11489891, GO:0006470=GO_REF:0000033, GO:0016311=PMID:11489891, GO:0016023=GO_REF:0000039, GO:0004721=PMID:11489891, GO:0005634=PMID:11489891, GO:0045204=PMID:11489891, GO:0017017=GO_REF:0000033, GO:0004725=GO_REF:0000003} Q9BY84 Dual specificity protein phosphatase 16 protein 20020502 {GO:0045209=TAS, GO:0000188=TAS, GO:0016791=IEA, GO:0005737=TAS, GO:0006470=IBA, GO:0016311=TAS, GO:0016023=IEA, GO:0004721=TAS, GO:0005634=TAS, GO:0045204=TAS, GO:0017017=IBA, GO:0004725=IEA} MAPK export from nucleus, MAPK phosphatase export from nucleus, leptomycin B sensitive, dephosphorylation, inactivation of MAPK activity, protein dephosphorylation cytoplasm, cytoplasmic membrane-bounded vesicle, nucleus MAP kinase tyrosine/serine/threonine phosphatase activity, phosphatase activity, phosphoprotein phosphatase activity, protein tyrosine phosphatase activity Human DUSP19 BHF-UCL UniProtKB {GO:0008330=GO_REF:0000019, GO:0007254=GO_REF:0000033, GO:0046330=GO_REF:0000024, GO:0031435=GO_REF:0000024, GO:0030295=GO_REF:0000024, GO:0000188=GO_REF:0000019, GO:0005737=GO_REF:0000033, GO:0008579=GO_REF:0000033, GO:0006470=GO_REF:0000033, GO:0046329=GO_REF:0000024, GO:0045860=GO_REF:0000024, GO:0004860=GO_REF:0000024, GO:0043507=GO_REF:0000024, GO:0006469=GO_REF:0000024, GO:0043410=GO_REF:0000024, GO:0043508=GO_REF:0000024, GO:0005078=GO_REF:0000024, GO:0004725=GO_REF:0000003} Q8WTR2 Dual specificity protein phosphatase 19 protein 20110301 {GO:0008330=IEA, GO:0007254=IBA, GO:0046330=ISS, GO:0031435=ISS, GO:0030295=ISS, GO:0000188=IEA, GO:0005737=IBA, GO:0008579=IBA, GO:0006470=IBA, GO:0046329=ISS, GO:0045860=ISS, GO:0004860=ISS, GO:0043507=ISS, GO:0006469=ISS, GO:0043410=ISS, GO:0043508=ISS, GO:0005078=ISS, GO:0004725=IEA} JNK cascade, inactivation of MAPK activity, negative regulation of JNK cascade, negative regulation of JUN kinase activity, negative regulation of protein kinase activity, positive regulation of JNK cascade, positive regulation of JUN kinase activity, positive regulation of MAPK cascade, positive regulation of protein kinase activity, protein dephosphorylation cytoplasm JUN kinase phosphatase activity, MAP-kinase scaffold activity, mitogen-activated protein kinase kinase kinase binding, protein kinase activator activity, protein kinase inhibitor activity, protein tyrosine phosphatase activity, protein tyrosine/threonine phosphatase activity Human UniProtKB:Q8K4T5 DUSP2 GOC UniProtKB {GO:0005515=PMID:21784977, GO:0000188=GO_REF:0000033, GO:0001706=GO_REF:0000033, GO:0006470=GO_REF:0000033, GO:0008330=PMID:8107850, GO:0005634=PMID:8107850, GO:0042981=GO_REF:0000033, GO:0005654=GO_REF:0000033, GO:0035335=PMID:7681221, GO:0017017=GO_REF:0000033, GO:0004725=GO_REF:0000003, GO:0051019=GO_REF:0000019} Q05923 Dual specificity protein phosphatase 2 protein 20130413 {GO:0005515=IPI, GO:0000188=IBA, GO:0001706=IBA, GO:0006470=IBA, GO:0008330=TAS, GO:0005634=TAS, GO:0042981=IBA, GO:0005654=IBA, GO:0035335=TAS, GO:0017017=IBA, GO:0004725=IEA, GO:0051019=IEA} endoderm formation, inactivation of MAPK activity, peptidyl-tyrosine dephosphorylation, protein dephosphorylation, regulation of apoptotic process nucleoplasm, nucleus MAP kinase tyrosine/serine/threonine phosphatase activity, mitogen-activated protein kinase binding, protein binding, protein tyrosine phosphatase activity, protein tyrosine/threonine phosphatase activity Human DUSP21 UniProtKB UniProtKB {GO:0005737=PMID:12408986, GO:0005743=GO_REF:0000039, GO:0005634=PMID:12408986, GO:0008138=GO_REF:0000033, GO:0035335=PMID:12408986, GO:0004725=PMID:12408986, GO:0017017=GO_REF:0000002} Q9H596 Dual specificity protein phosphatase 21 protein 20100322 {GO:0005737=IDA, GO:0005743=IEA, GO:0005634=IDA, GO:0008138=IBA, GO:0035335=IDA, GO:0004725=IDA, GO:0017017=IEA} peptidyl-tyrosine dephosphorylation cytoplasm, mitochondrial inner membrane, nucleus MAP kinase tyrosine/serine/threonine phosphatase activity, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human DUSP22 PINC UniProtKB {GO:0008283=PMID:9205128, GO:0046330=GO_REF:0000033, GO:0006915=PMID:9205128, GO:0005634=GO_REF:0000039, GO:0007275=PMID:9205128, GO:0000122=PMID:16636663, GO:0000188=PMID:9205128, GO:0005737=GO_REF:0000039, GO:0006470=GO_REF:0000033, GO:0042127=GO_REF:0000033, GO:0007179=GO_REF:0000033, GO:0008138=GO_REF:0000033, GO:0004725=GO_REF:0000003} Q9NRW4 Dual specificity protein phosphatase 22 protein 20030904 {GO:0008283=TAS, GO:0046330=IBA, GO:0006915=TAS, GO:0005634=IEA, GO:0007275=TAS, GO:0000122=IMP, GO:0000188=TAS, GO:0005737=IEA, GO:0006470=IBA, GO:0042127=IBA, GO:0007179=IBA, GO:0008138=IBA, GO:0004725=IEA} apoptotic process, cell proliferation, inactivation of MAPK activity, multicellular organismal development, negative regulation of transcription from RNA polymerase II promoter, positive regulation of JNK cascade, protein dephosphorylation, regulation of cell proliferation, transforming growth factor beta receptor signaling pathway cytoplasm, nucleus protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human DUSP23 HPA UniProtKB {GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008138=GO_REF:0000002, GO:0004725=GO_REF:0000003, GO:0043231=GO_REF:0000052, GO:0005829=GO_REF:0000039} Q9BVJ7 Dual specificity protein phosphatase 23 protein 20111111 {GO:0005730=IDA, GO:0005634=IDA, GO:0008138=IEA, GO:0004725=IEA, GO:0043231=IDA, GO:0005829=IEA} cytosol, intracellular membrane-bounded organelle, nucleolus, nucleus protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human DUSP26 IntAct UniProtKB {GO:0005515=PMID:20562916, GO:0005739=GO_REF:0000019, GO:0005794=GO_REF:0000039, GO:0006470=GO_REF:0000033, GO:0005634=GO_REF:0000039, GO:0008138=GO_REF:0000033, GO:0004725=GO_REF:0000003} Q9BV47 Dual specificity protein phosphatase 26 protein 20130415 {GO:0005515=IPI, GO:0005739=IEA, GO:0005794=IEA, GO:0006470=IBA, GO:0005634=IEA, GO:0008138=IBA, GO:0004725=IEA} protein dephosphorylation Golgi apparatus, mitochondrion, nucleus protein binding, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human UniProtKB:P04637 DUSP28 RefGenome UniProtKB {GO:0006470=GO_REF:0000002, GO:0008138=GO_REF:0000033, GO:0035335=GO_REF:0000033, GO:0004725=GO_REF:0000003} Q4G0W2 Dual specificity phosphatase 28 protein 20110118 {GO:0006470=IEA, GO:0008138=IBA, GO:0035335=IBA, GO:0004725=IEA} peptidyl-tyrosine dephosphorylation, protein dephosphorylation protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human PANTHER:PTN000017471 DUSP3 InterPro UniProtKB {GO:0033549=PMID:16604064, GO:0034142=Reactome:REACT_6894, GO:0005634=PMID:16604064, GO:0051403=Reactome:REACT_21308, GO:0035335=PMID:7876121, GO:0005829=PMID:12447358, GO:0043409=PMID:16604064, GO:0000188=PMID:16604064, GO:0002756=Reactome:REACT_6809, GO:0046329=PMID:11085983, GO:0006470=GO_REF:0000002, GO:0002755=Reactome:REACT_27215, GO:0070373=PMID:11085983, GO:0034138=Reactome:REACT_6783, GO:0004725=GO_REF:0000002, GO:0001772=PMID:12447358, GO:0048011=Reactome:REACT_11061, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0050868=PMID:12447358, GO:0034134=Reactome:REACT_7980, GO:0002224=Reactome:REACT_9020, GO:0050860=PMID:12447358, GO:0045931=PMID:16604064, GO:0045087=Reactome:REACT_6802, GO:0005654=Reactome:REACT_12439, GO:0034166=Reactome:REACT_9027, GO:0035666=Reactome:REACT_25281, GO:0008138=GO_REF:0000002, GO:0034146=Reactome:REACT_9061, GO:0034162=Reactome:REACT_9047} Q8IYJ9 DUSP3 protein protein 20130413 {GO:0033549=IMP, GO:0034142=TAS, GO:0005634=IDA, GO:0051403=TAS, GO:0035335=IDA, GO:0005829=IDA, GO:0043409=IMP, GO:0000188=IMP, GO:0002756=TAS, GO:0046329=IDA, GO:0006470=IEA, GO:0002755=TAS, GO:0070373=IDA, GO:0034138=TAS, GO:0004725=IEA, GO:0001772=IDA, GO:0048011=TAS, GO:0038124=TAS, GO:0038123=TAS, GO:0050868=IDA, GO:0034134=TAS, GO:0002224=TAS, GO:0050860=IDA, GO:0045931=IMP, GO:0045087=TAS, GO:0005654=TAS, GO:0034166=TAS, GO:0035666=TAS, GO:0008138=IEA, GO:0034146=TAS, GO:0034162=TAS} MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, inactivation of MAPK activity, innate immune response, negative regulation of ERK1 and ERK2 cascade, negative regulation of JNK cascade, negative regulation of MAPK cascade, negative regulation of T cell activation, negative regulation of T cell receptor signaling pathway, neurotrophin TRK receptor signaling pathway, peptidyl-tyrosine dephosphorylation, positive regulation of mitotic cell cycle, protein dephosphorylation, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway cytosol, immunological synapse, nucleoplasm, nucleus MAP kinase phosphatase activity, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human InterPro:IPR000340|InterPro:IPR020405|InterPro:IPR020417|InterPro:IPR020422|InterPro:IPR024950 DUSP4 Reactome UniProtKB {GO:0048011=Reactome:REACT_11061, GO:0001706=GO_REF:0000033, GO:0038124=Reactome:REACT_8006, GO:0034142=Reactome:REACT_6894, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0008330=PMID:7535768, GO:0005634=PMID:7535768, GO:0002224=Reactome:REACT_9020, GO:0051403=Reactome:REACT_21308, GO:0000188=GO_REF:0000033, GO:0002756=Reactome:REACT_6809, GO:0006470=GO_REF:0000033, GO:0000165=PMID:7535768, GO:0045087=Reactome:REACT_6802, GO:0002755=Reactome:REACT_27215, GO:0034166=Reactome:REACT_9027, GO:0005654=Reactome:REACT_12439, GO:0035666=Reactome:REACT_25281, GO:0034146=Reactome:REACT_9061, GO:0034138=Reactome:REACT_6783, GO:0034162=Reactome:REACT_9047, GO:0004725=GO_REF:0000003, GO:0017017=GO_REF:0000033} Q13115 Dual specificity protein phosphatase 4 protein 20130301 {GO:0048011=TAS, GO:0001706=IBA, GO:0038124=TAS, GO:0034142=TAS, GO:0038123=TAS, GO:0034134=TAS, GO:0008330=TAS, GO:0005634=TAS, GO:0002224=TAS, GO:0051403=TAS, GO:0000188=IBA, GO:0002756=TAS, GO:0006470=IBA, GO:0000165=TAS, GO:0045087=TAS, GO:0002755=TAS, GO:0034166=TAS, GO:0005654=TAS, GO:0035666=TAS, GO:0034146=TAS, GO:0034138=TAS, GO:0034162=TAS, GO:0004725=IEA, GO:0017017=IBA} MAPK cascade, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, endoderm formation, inactivation of MAPK activity, innate immune response, neurotrophin TRK receptor signaling pathway, protein dephosphorylation, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway nucleoplasm, nucleus MAP kinase tyrosine/serine/threonine phosphatase activity, protein tyrosine phosphatase activity, protein tyrosine/threonine phosphatase activity Human DUSP5 GOC UniProtKB {GO:0000188=GO_REF:0000033, GO:0001706=GO_REF:0000033, GO:0006470=GO_REF:0000033, GO:0005654=GO_REF:0000033, GO:0035335=PMID:7961985, GO:0017017=GO_REF:0000033, GO:0004725=GO_REF:0000003} Q16690 Dual specificity protein phosphatase 5 protein 20130413 {GO:0000188=IBA, GO:0001706=IBA, GO:0006470=IBA, GO:0005654=IBA, GO:0035335=TAS, GO:0017017=IBA, GO:0004725=IEA} endoderm formation, inactivation of MAPK activity, peptidyl-tyrosine dephosphorylation, protein dephosphorylation nucleoplasm MAP kinase tyrosine/serine/threonine phosphatase activity, protein tyrosine phosphatase activity Human DUSP6 Reactome UniProtKB {GO:0014070=GO_REF:0000019, GO:0034142=Reactome:REACT_6894, GO:0042663=GO_REF:0000033, GO:0060420=GO_REF:0000033, GO:0009953=GO_REF:0000033, GO:0051409=PMID:10846176, GO:0051403=Reactome:REACT_21308, GO:0030154=GO_REF:0000019, GO:0035335=PMID:8670865, GO:0005829=GO_REF:0000033, GO:0000188=PMID:8670865, GO:0002756=Reactome:REACT_6809, GO:0005737=PMID:9788880, GO:0006470=GO_REF:0000019, GO:0002755=Reactome:REACT_27215, GO:0070373=PMID:18771677, GO:0034138=Reactome:REACT_6783, GO:0004725=GO_REF:0000003, GO:0017017=PMID:8670865, GO:0048011=Reactome:REACT_11061, GO:0038124=Reactome:REACT_8006, GO:0043065=PMID:10846176, GO:0038123=Reactome:REACT_8005, GO:0042493=GO_REF:0000019, GO:0034134=Reactome:REACT_7980, GO:0070848=GO_REF:0000019, GO:0002224=Reactome:REACT_9020, GO:0040036=GO_REF:0000033, GO:0045087=Reactome:REACT_6802, GO:0001933=GO_REF:0000019, GO:0035666=Reactome:REACT_25281, GO:0034166=Reactome:REACT_9027, GO:0005654=Reactome:REACT_12439, GO:0008138=GO_REF:0000019, GO:0034146=Reactome:REACT_9061, GO:0034162=Reactome:REACT_9047} Q16828 Dual specificity protein phosphatase 6 protein 20130301 {GO:0014070=IEA, GO:0034142=TAS, GO:0042663=IBA, GO:0060420=IBA, GO:0009953=IBA, GO:0051409=IEP, GO:0051403=TAS, GO:0030154=IEA, GO:0035335=IDA, GO:0005829=IBA, GO:0000188=IDA, GO:0002756=TAS, GO:0005737=IDA, GO:0006470=IEA, GO:0002755=TAS, GO:0070373=IMP, GO:0034138=TAS, GO:0004725=IEA, GO:0017017=IDA, GO:0048011=TAS, GO:0038124=TAS, GO:0043065=IDA, GO:0038123=TAS, GO:0042493=IEA, GO:0034134=TAS, GO:0070848=IEA, GO:0002224=TAS, GO:0040036=IBA, GO:0045087=TAS, GO:0001933=IEA, GO:0035666=TAS, GO:0034166=TAS, GO:0005654=TAS, GO:0008138=IEA, GO:0034146=TAS, GO:0034162=TAS} MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, cell differentiation, dorsal/ventral pattern formation, inactivation of MAPK activity, innate immune response, negative regulation of ERK1 and ERK2 cascade, negative regulation of protein phosphorylation, neurotrophin TRK receptor signaling pathway, peptidyl-tyrosine dephosphorylation, positive regulation of apoptotic process, protein dephosphorylation, regulation of endodermal cell fate specification, regulation of fibroblast growth factor receptor signaling pathway, regulation of heart growth, response to drug, response to growth factor stimulus, response to nitrosative stress, response to organic cyclic compound, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway cytoplasm, cytosol, nucleoplasm MAP kinase tyrosine/serine/threonine phosphatase activity, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human DUSP7 IntAct UniProtKB {GO:0005515=PMID:12907755, GO:0048011=Reactome:REACT_11061, GO:0038124=Reactome:REACT_8006, GO:0034142=Reactome:REACT_6894, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0002224=Reactome:REACT_9020, GO:0051403=Reactome:REACT_21308, GO:0035335=PMID:9788880, GO:0005829=PMID:9788880, GO:0000188=GO_REF:0000033, GO:0002756=Reactome:REACT_6809, GO:0006470=GO_REF:0000002, GO:0043407=PMID:9788880, GO:0002755=Reactome:REACT_27215, GO:0045087=Reactome:REACT_6802, GO:0034166=Reactome:REACT_9027, GO:0005654=Reactome:REACT_12439, GO:0035666=Reactome:REACT_25281, GO:0034146=Reactome:REACT_9061, GO:0034138=Reactome:REACT_6783, GO:0034162=Reactome:REACT_9047, GO:0017017=PMID:9788880, GO:0004725=GO_REF:0000003} Q16829 Dual specificity protein phosphatase 7 protein 20130415 {GO:0005515=IPI, GO:0048011=TAS, GO:0038124=TAS, GO:0034142=TAS, GO:0038123=TAS, GO:0034134=TAS, GO:0002224=TAS, GO:0051403=TAS, GO:0035335=IDA, GO:0005829=IDA, GO:0000188=IBA, GO:0002756=TAS, GO:0006470=IEA, GO:0043407=IDA, GO:0002755=TAS, GO:0045087=TAS, GO:0034166=TAS, GO:0005654=TAS, GO:0035666=TAS, GO:0034146=TAS, GO:0034138=TAS, GO:0034162=TAS, GO:0017017=IDA, GO:0004725=IEA} MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, inactivation of MAPK activity, innate immune response, negative regulation of MAP kinase activity, neurotrophin TRK receptor signaling pathway, peptidyl-tyrosine dephosphorylation, protein dephosphorylation, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway cytosol, nucleoplasm MAP kinase tyrosine/serine/threonine phosphatase activity, protein binding, protein tyrosine phosphatase activity Human UniProtKB:P10912 DUSP8 GOC UniProtKB {GO:0000188=GO_REF:0000033, GO:0005737=GO_REF:0000033, GO:0006470=GO_REF:0000033, GO:0005634=GO_REF:0000033, GO:0035335=PMID:7561881, GO:0017017=GO_REF:0000033, GO:0004725=GO_REF:0000003} Q13202 Dual specificity protein phosphatase 8 protein 20130413 {GO:0000188=IBA, GO:0005737=IBA, GO:0006470=IBA, GO:0005634=IBA, GO:0035335=TAS, GO:0017017=IBA, GO:0004725=IEA} inactivation of MAPK activity, peptidyl-tyrosine dephosphorylation, protein dephosphorylation cytoplasm, nucleus MAP kinase tyrosine/serine/threonine phosphatase activity, protein tyrosine phosphatase activity Human DUSP9 HPA UniProtKB {GO:0000188=GO_REF:0000033, GO:0005737=PMID:9030581, GO:0006470=GO_REF:0000033, GO:0005783=GO_REF:0000052, GO:0007254=PMID:9030581, GO:0005634=PMID:9030581, GO:0004721=PMID:9030581, GO:0004725=GO_REF:0000003, GO:0017017=GO_REF:0000033, GO:0005829=GO_REF:0000033} Q99956 Dual specificity protein phosphatase 9 protein 20080818 {GO:0000188=IBA, GO:0005737=TAS, GO:0006470=IBA, GO:0005783=IDA, GO:0007254=TAS, GO:0005634=TAS, GO:0004721=TAS, GO:0004725=IEA, GO:0017017=IBA, GO:0005829=IBA} JNK cascade, inactivation of MAPK activity, protein dephosphorylation cytoplasm, cytosol, endoplasmic reticulum, nucleus MAP kinase tyrosine/serine/threonine phosphatase activity, phosphoprotein phosphatase activity, protein tyrosine phosphatase activity Human DUT IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0046080=GO_REF:0000002, GO:0005634=PMID:8631816, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0006226=GO_REF:0000041, GO:0005739=GO_REF:0000039, GO:0006260=PMID:1325640, GO:0006139=PMID:1325640, GO:0046134=Reactome:REACT_21376, GO:0004170=Reactome:REACT_150, GO:0005654=Reactome:REACT_150, GO:0006206=Reactome:REACT_957} P33316 Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial protein 20130415 {GO:0005515=IPI, GO:0046080=IEA, GO:0005634=TAS, GO:0055086=TAS, GO:0044281=TAS, GO:0006226=IEA, GO:0005739=IEA, GO:0006260=TAS, GO:0006139=TAS, GO:0046134=TAS, GO:0004170=EXP, GO:0005654=TAS, GO:0006206=TAS} DNA replication, dUMP biosynthetic process, dUTP metabolic process, nucleobase-containing compound metabolic process, nucleobase-containing small molecule metabolic process, pyrimidine nucleobase metabolic process, pyrimidine nucleoside biosynthetic process, small molecule metabolic process mitochondrion, nucleoplasm, nucleus dUTP diphosphatase activity, protein binding Human UniProtKB:Q6ZVK8 DUX4 UniProtKB UniProtKB {GO:0000976=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q9UBX2 Double homeobox protein 4 protein 20130413 {GO:0000976=IEA, GO:0003700=IEA, GO:0005634=IEA, GO:0006351=IEA} transcription, DNA-dependent nucleus sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding Human UniProtKB-SubCell:SL-0191 DVL1 BHF-UCL UniProtKB {GO:0005515=PMID:20412773, GO:0034504=PMID:10330181, GO:0006366=PMID:11742073, GO:0090263=GO_REF:0000019, GO:0045202=GO_REF:0000024, GO:0035372=GO_REF:0000019, GO:0031122=GO_REF:0000019, GO:0042802=PMID:10330181, GO:0005109=PMID:19388021, GO:0007411=GO_REF:0000033, GO:0043025=GO_REF:0000033, GO:0005938=GO_REF:0000033, GO:0019901=PMID:19643732, GO:0060134=GO_REF:0000019, GO:0050808=GO_REF:0000024, GO:0001505=GO_REF:0000024, GO:0010976=GO_REF:0000019, GO:0035176=GO_REF:0000019, GO:0019899=PMID:19643732, GO:0045893=PMID:17593335, GO:0071340=GO_REF:0000033, GO:0032091=PMID:19643732, GO:0030424=GO_REF:0000033, GO:0030136=GO_REF:0000033, GO:0030177=PMID:11113207, GO:0048675=GO_REF:0000033, GO:0030425=GO_REF:0000033, GO:0007269=GO_REF:0000024, GO:0030426=GO_REF:0000033, GO:0005829=GO_REF:0000039, GO:0035556=GO_REF:0000002, GO:0060026=GO_REF:0000033, GO:0007528=GO_REF:0000024, GO:0048668=GO_REF:0000033, GO:0090103=GO_REF:0000033, GO:0004871=GO_REF:0000002, GO:0022007=GO_REF:0000019, GO:0060070=PMID:17593335, GO:0060071=PMID:12805222, GO:0005874=GO_REF:0000033, GO:0090179=GO_REF:0000033, GO:0031410=PMID:11113207, GO:0016328=PMID:20177058, GO:0048813=GO_REF:0000024, GO:0048365=GO_REF:0000033, GO:0021915=PMID:8817329, GO:0016023=GO_REF:0000024, GO:0043113=GO_REF:0000024, GO:0006469=PMID:10330181} O14640 Segment polarity protein dishevelled homolog DVL-1 protein 20101206 {GO:0005515=IPI, GO:0034504=IMP, GO:0006366=IDA, GO:0090263=IEA, GO:0045202=ISS, GO:0035372=IEA, GO:0031122=IEA, GO:0042802=IPI, GO:0005109=IPI, GO:0007411=IBA, GO:0043025=IBA, GO:0005938=IBA, GO:0019901=IPI, GO:0060134=IEA, GO:0050808=ISS, GO:0001505=ISS, GO:0010976=IEA, GO:0035176=IEA, GO:0019899=IPI, GO:0045893=IDA, GO:0071340=IBA, GO:0032091=IDA, GO:0030424=IBA, GO:0030136=IBA, GO:0030177=IDA, GO:0048675=IBA, GO:0030425=IBA, GO:0007269=ISS, GO:0030426=IBA, GO:0005829=IEA, GO:0035556=IEA, GO:0060026=IBA, GO:0007528=ISS, GO:0048668=IBA, GO:0090103=IBA, GO:0004871=IEA, GO:0022007=IEA, GO:0060070=IDA, GO:0060071=IDA, GO:0005874=IBA, GO:0090179=IBA, GO:0031410=IDA, GO:0016328=IDA, GO:0048813=ISS, GO:0048365=IBA, GO:0021915=IEP, GO:0016023=ISS, GO:0043113=ISS, GO:0006469=IDA} Wnt receptor signaling pathway, planar cell polarity pathway, axon extension, axon guidance, canonical Wnt receptor signaling pathway, cochlea morphogenesis, collateral sprouting, convergent extension, convergent extension involved in neural plate elongation, cytoplasmic microtubule organization, dendrite morphogenesis, intracellular signal transduction, negative regulation of protein binding, negative regulation of protein kinase activity, neural tube development, neuromuscular junction development, neurotransmitter secretion, planar cell polarity pathway involved in neural tube closure, positive regulation of Wnt receptor signaling pathway, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of neuron projection development, positive regulation of transcription, DNA-dependent, prepulse inhibition, protein localization to microtubule, protein localization to nucleus, receptor clustering, regulation of neurotransmitter levels, skeletal muscle acetylcholine-gated channel clustering, social behavior, synapse organization, transcription from RNA polymerase II promoter axon, cell cortex, clathrin-coated vesicle, cytoplasmic membrane-bounded vesicle, cytoplasmic vesicle, cytosol, dendrite, growth cone, lateral plasma membrane, microtubule, neuronal cell body, synapse Rac GTPase binding, enzyme binding, frizzled binding, identical protein binding, protein binding, protein kinase binding, signal transducer activity Human UniProtKB:Q9GZV5 DVL2 BHF-UCL UniProtKB {GO:0005515=PMID:20412773, GO:0021535=GO_REF:0000033, GO:0005886=GO_REF:0000033, GO:0006366=PMID:11742073, GO:0061098=GO_REF:0000019, GO:0090263=GO_REF:0000019, GO:0030136=GO_REF:0000033, GO:0005634=GO_REF:0000024, GO:0043621=GO_REF:0000019, GO:0042802=PMID:16189514, GO:0005829=Reactome:REACT_118667, GO:0007507=GO_REF:0000024, GO:0035556=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0005109=PMID:19388021, GO:0044340=PMID:18787224, GO:0005737=PMID:9192851, GO:0051091=PMID:17593335, GO:0060026=GO_REF:0000033, GO:0090103=GO_REF:0000033, GO:0043507=PMID:19137009, GO:0004871=GO_REF:0000002, GO:0022007=GO_REF:0000019, GO:0016055=PMID:16446366, GO:0060070=PMID:17593335, GO:0005938=GO_REF:0000033, GO:0060071=PMID:12805222, GO:0007379=GO_REF:0000024, GO:0019904=GO_REF:0000019, GO:0090179=GO_REF:0000033, GO:0001843=GO_REF:0000024, GO:0045177=GO_REF:0000033, GO:0007275=GO_REF:0000002, GO:0035329=Reactome:REACT_118607, GO:0003151=GO_REF:0000024, GO:0003007=GO_REF:0000033, GO:0001934=PMID:20137080, GO:0034613=GO_REF:0000019, GO:0045893=PMID:17593335, GO:0035567=PMID:19137009} O14641 Segment polarity protein dishevelled homolog DVL-2 protein 20100930 {GO:0005515=IPI, GO:0021535=IBA, GO:0005886=IBA, GO:0006366=IDA, GO:0061098=IEA, GO:0090263=IEA, GO:0030136=IBA, GO:0005634=ISS, GO:0043621=IEA, GO:0042802=IPI, GO:0005829=TAS, GO:0007507=ISS, GO:0035556=IEA, GO:0005622=IEA, GO:0005109=IPI, GO:0044340=IDA, GO:0005737=IDA, GO:0051091=IDA, GO:0060026=IBA, GO:0090103=IBA, GO:0043507=IMP, GO:0004871=IEA, GO:0022007=IEA, GO:0016055=IGI, GO:0060070=IDA, GO:0005938=IBA, GO:0060071=IDA, GO:0007379=ISS, GO:0019904=IEA, GO:0090179=IBA, GO:0001843=ISS, GO:0045177=IBA, GO:0007275=IEA, GO:0035329=TAS, GO:0003151=ISS, GO:0003007=IBA, GO:0001934=IMP, GO:0034613=IEA, GO:0045893=IDA, GO:0035567=IMP} Wnt receptor signaling pathway, Wnt receptor signaling pathway, planar cell polarity pathway, canonical Wnt receptor signaling pathway, canonical Wnt receptor signaling pathway involved in regulation of cell proliferation, cell migration in hindbrain, cellular protein localization, cochlea morphogenesis, convergent extension, convergent extension involved in neural plate elongation, heart development, heart morphogenesis, hippo signaling cascade, intracellular signal transduction, multicellular organismal development, neural tube closure, non-canonical Wnt receptor signaling pathway, outflow tract morphogenesis, planar cell polarity pathway involved in neural tube closure, positive regulation of JUN kinase activity, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of protein phosphorylation, positive regulation of protein tyrosine kinase activity, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription, DNA-dependent, segment specification, transcription from RNA polymerase II promoter apical part of cell, cell cortex, clathrin-coated vesicle, cytoplasm, cytosol, intracellular, nucleus, plasma membrane frizzled binding, identical protein binding, protein binding, protein domain specific binding, protein self-association, signal transducer activity Human DVL3 BHF-UCL UniProtKB {GO:0005515=PMID:20412773, GO:0008013=PMID:10644691, GO:0038031=GO_REF:0000024, GO:0002020=PMID:20227366, GO:0035556=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0005109=PMID:19388021, GO:0060026=GO_REF:0000033, GO:0005737=GO_REF:0000019, GO:0090103=GO_REF:0000033, GO:0004871=GO_REF:0000002, GO:0043507=PMID:19137009, GO:0016055=PMID:10644691, GO:0005938=GO_REF:0000033, GO:0060070=PMID:20137080, GO:0060071=PMID:12805222, GO:0046982=PMID:19137009, GO:0042493=GO_REF:0000019, GO:0090179=GO_REF:0000033, GO:0005102=PMID:17030191, GO:0007275=GO_REF:0000002, GO:0003148=GO_REF:0000033, GO:0001934=PMID:20137080, GO:0045893=PMID:10644691, GO:0035567=PMID:19137009} Q92997 Segment polarity protein dishevelled homolog DVL-3 protein 20100806 {GO:0005515=IPI, GO:0008013=IDA, GO:0038031=ISS, GO:0002020=IPI, GO:0035556=IEA, GO:0005622=IEA, GO:0005109=IPI, GO:0060026=IBA, GO:0005737=IEA, GO:0090103=IBA, GO:0004871=IEA, GO:0043507=IMP, GO:0016055=IDA, GO:0005938=IBA, GO:0060070=IMP, GO:0060071=IDA, GO:0046982=IDA, GO:0042493=IEA, GO:0090179=IBA, GO:0005102=IPI, GO:0007275=IEA, GO:0003148=IBA, GO:0001934=IMP, GO:0045893=IDA, GO:0035567=IMP} Wnt receptor signaling pathway, Wnt receptor signaling pathway, planar cell polarity pathway, canonical Wnt receptor signaling pathway, cochlea morphogenesis, convergent extension, intracellular signal transduction, multicellular organismal development, non-canonical Wnt receptor signaling pathway, non-canonical Wnt receptor signaling pathway via JNK cascade, outflow tract septum morphogenesis, planar cell polarity pathway involved in neural tube closure, positive regulation of JUN kinase activity, positive regulation of protein phosphorylation, positive regulation of transcription, DNA-dependent, response to drug cell cortex, cytoplasm, intracellular beta-catenin binding, frizzled binding, protease binding, protein binding, protein heterodimerization activity, receptor binding, signal transducer activity Human DYDC1 null null {} null null null null {} null null null DYDC2 null null {} null null null null {} null null null DYM HPA UniProtKB {GO:0005515=PMID:21280149, GO:0060348=PMID:21280149, GO:0005737=GO_REF:0000052, GO:0005794=PMID:21280149, GO:0005886=GO_REF:0000052, GO:0007030=PMID:21280149, GO:0005634=GO_REF:0000052, GO:0019899=PMID:21280149} Q7RTS9 Dymeclin protein 20110516 {GO:0005515=IPI, GO:0060348=IMP, GO:0005737=IDA, GO:0005794=IDA, GO:0005886=IDA, GO:0007030=IMP, GO:0005634=IDA, GO:0019899=IPI} Golgi organization, bone development Golgi apparatus, cytoplasm, nucleus, plasma membrane enzyme binding, protein binding Human DYNC1H1 HPA UniProtKB {GO:0005515=PMID:21163940, GO:0008219=GO_REF:0000037, GO:0005813=PMID:21399614, GO:0005794=GO_REF:0000052, GO:0033962=GO_REF:0000024, GO:0042623=GO_REF:0000029, GO:0005874=PMID:21525035, GO:0003777=GO_REF:0000029, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_120995, GO:0019886=Reactome:REACT_121399, GO:0005737=GO_REF:0000052, GO:0034063=GO_REF:0000024, GO:0000086=Reactome:REACT_2203, GO:0006810=GO_REF:0000037, GO:0005868=PMID:8666668, GO:0007052=PMID:8227145, GO:0000278=Reactome:REACT_152, GO:0007018=GO_REF:0000029} Q14204 Cytoplasmic dynein 1 heavy chain 1 protein 20080205 {GO:0005515=IPI, GO:0008219=IEA, GO:0005813=IDA, GO:0005794=IDA, GO:0033962=ISS, GO:0042623=NAS, GO:0005874=IDA, GO:0003777=NAS, GO:0005524=IEA, GO:0005829=TAS, GO:0019886=TAS, GO:0005737=IDA, GO:0034063=ISS, GO:0000086=TAS, GO:0006810=IEA, GO:0005868=NAS, GO:0007052=NAS, GO:0000278=TAS, GO:0007018=NAS} G2/M transition of mitotic cell cycle, antigen processing and presentation of exogenous peptide antigen via MHC class II, cell death, cytoplasmic mRNA processing body assembly, microtubule-based movement, mitotic cell cycle, mitotic spindle organization, stress granule assembly, transport Golgi apparatus, centrosome, cytoplasm, cytoplasmic dynein complex, cytosol, microtubule ATP binding, ATPase activity, coupled, microtubule motor activity, protein binding Human DYNC1I1 HGNC UniProtKB {GO:0005515=PMID:14985359, GO:0008017=GO_REF:0000024, GO:0048471=GO_REF:0000024, GO:0005874=GO_REF:0000037, GO:0003777=GO_REF:0000024, GO:0031982=PMID:20682791, GO:0005829=Reactome:REACT_120995, GO:0019886=Reactome:REACT_121399, GO:0000922=PMID:19229290, GO:0003774=PMID:10049579, GO:0047496=GO_REF:0000024, GO:0000777=GO_REF:0000039, GO:0000776=PMID:19229290, GO:0005868=GO_REF:0000024, GO:0007018=GO_REF:0000002} O14576 Cytoplasmic dynein 1 intermediate chain 1 protein 20070412 {GO:0005515=IPI, GO:0008017=ISS, GO:0048471=ISS, GO:0005874=IEA, GO:0003777=ISS, GO:0031982=IDA, GO:0005829=TAS, GO:0019886=TAS, GO:0000922=IDA, GO:0003774=TAS, GO:0047496=ISS, GO:0000777=IEA, GO:0000776=IDA, GO:0005868=ISS, GO:0007018=IEA} antigen processing and presentation of exogenous peptide antigen via MHC class II, microtubule-based movement, vesicle transport along microtubule condensed chromosome kinetochore, cytoplasmic dynein complex, cytosol, kinetochore, microtubule, perinuclear region of cytoplasm, spindle pole, vesicle microtubule binding, microtubule motor activity, motor activity, protein binding Human UniProtKB:Q63100 DYNC1I2 Reactome UniProtKB {GO:0005813=PMID:21399614, GO:0005874=PMID:21525035, GO:0003777=PMID:8522607, GO:0031982=PMID:20682791, GO:0005829=Reactome:REACT_120995, GO:0019886=Reactome:REACT_121399, GO:0005737=PMID:8522607, GO:0019048=GO_REF:0000037, GO:0000086=Reactome:REACT_2203, GO:0006810=GO_REF:0000037, GO:0005868=GO_REF:0000002, GO:0000278=Reactome:REACT_152, GO:0007018=PMID:8522607} Q13409 Cytoplasmic dynein 1 intermediate chain 2 protein 20130301 {GO:0005813=IDA, GO:0005874=IDA, GO:0003777=NAS, GO:0031982=IDA, GO:0005829=TAS, GO:0019886=TAS, GO:0005737=NAS, GO:0019048=IEA, GO:0000086=TAS, GO:0006810=IEA, GO:0005868=IEA, GO:0000278=TAS, GO:0007018=NAS} G2/M transition of mitotic cell cycle, antigen processing and presentation of exogenous peptide antigen via MHC class II, microtubule-based movement, mitotic cell cycle, transport, virus-host interaction centrosome, cytoplasm, cytoplasmic dynein complex, cytosol, microtubule, vesicle microtubule motor activity Human DYNC1LI1 HPA UniProtKB {GO:0005813=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005874=GO_REF:0000037, GO:0090267=PMID:19229290, GO:0005524=GO_REF:0000037, GO:0000922=PMID:19229290, GO:0003774=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0007067=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0006810=GO_REF:0000037, GO:0000777=GO_REF:0000039, GO:0000776=PMID:19229290, GO:0005868=PMID:19229290, GO:0051301=GO_REF:0000037} Q9Y6G9 Cytoplasmic dynein 1 light intermediate chain 1 protein 20101115 {GO:0005813=IDA, GO:0005886=IDA, GO:0005874=IEA, GO:0090267=IMP, GO:0005524=IEA, GO:0000922=IDA, GO:0003774=IEA, GO:0005737=IDA, GO:0007067=IEA, GO:0019048=IEA, GO:0006810=IEA, GO:0000777=IEA, GO:0000776=IDA, GO:0005868=IDA, GO:0051301=IEA} cell division, mitosis, positive regulation of mitotic cell cycle spindle assembly checkpoint, transport, virus-host interaction centrosome, condensed chromosome kinetochore, cytoplasm, cytoplasmic dynein complex, kinetochore, microtubule, plasma membrane, spindle pole ATP binding, motor activity Human DYNC1LI2 Reactome UniProtKB {GO:0019886=Reactome:REACT_121399, GO:0005813=PMID:21399614, GO:0051642=GO_REF:0000019, GO:0003774=GO_REF:0000037, GO:0005874=GO_REF:0000037, GO:0006810=GO_REF:0000037, GO:0000226=GO_REF:0000019, GO:0005868=PMID:7738094, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_120995} O43237 Cytoplasmic dynein 1 light intermediate chain 2 protein 20130301 {GO:0019886=TAS, GO:0005813=IDA, GO:0051642=IEA, GO:0003774=IEA, GO:0005874=IEA, GO:0006810=IEA, GO:0000226=IEA, GO:0005868=TAS, GO:0005524=IEA, GO:0005829=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, centrosome localization, microtubule cytoskeleton organization, transport centrosome, cytoplasmic dynein complex, cytosol, microtubule ATP binding, motor activity Human DYNC2H1 Reactome UniProtKB {GO:0007368=GO_REF:0000019, GO:0005794=PMID:8666668, GO:0005886=GO_REF:0000039, GO:0001539=GO_REF:0000002, GO:0005874=PMID:21525035, GO:0045177=GO_REF:0000019, GO:0031512=GO_REF:0000019, GO:0009953=GO_REF:0000019, GO:0030326=GO_REF:0000019, GO:0035085=GO_REF:0000039, GO:0003777=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_120995, GO:0019886=Reactome:REACT_121399, GO:0042384=GO_REF:0000019, GO:0003774=PMID:8666668, GO:0030286=GO_REF:0000037, GO:0008105=GO_REF:0000019, GO:0016485=GO_REF:0000019, GO:0030031=GO_REF:0000002, GO:0007030=PMID:8666668, GO:0030900=GO_REF:0000019, GO:0016887=GO_REF:0000002, GO:0007018=GO_REF:0000002} Q8NCM8 Cytoplasmic dynein 2 heavy chain 1 protein 20130301 {GO:0007368=IEA, GO:0005794=IDA, GO:0005886=IEA, GO:0001539=IEA, GO:0005874=IDA, GO:0045177=IEA, GO:0031512=IEA, GO:0009953=IEA, GO:0030326=IEA, GO:0035085=IEA, GO:0003777=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0019886=TAS, GO:0042384=IEA, GO:0003774=NAS, GO:0030286=IEA, GO:0008105=IEA, GO:0016485=IEA, GO:0030031=IEA, GO:0007030=IDA, GO:0030900=IEA, GO:0016887=IEA, GO:0007018=IEA} Golgi organization, antigen processing and presentation of exogenous peptide antigen via MHC class II, asymmetric protein localization, cell projection assembly, ciliary or flagellar motility, cilium assembly, determination of left/right symmetry, dorsal/ventral pattern formation, embryonic limb morphogenesis, forebrain development, microtubule-based movement, protein processing Golgi apparatus, apical part of cell, cilium axoneme, cytosol, dynein complex, microtubule, motile primary cilium, plasma membrane ATP binding, ATPase activity, microtubule motor activity, motor activity Human DYNC2LI1 BHF-UCL UniProtKB {GO:0005881=GO_REF:0000024, GO:0007368=GO_REF:0000019, GO:0045177=GO_REF:0000024, GO:0031512=GO_REF:0000024, GO:0072372=GO_REF:0000024, GO:0035085=GO_REF:0000024, GO:0005829=Reactome:REACT_120995, GO:0042384=GO_REF:0000019, GO:0019886=Reactome:REACT_121399, GO:0003774=GO_REF:0000037, GO:0005858=PMID:12802074, GO:0030990=GO_REF:0000024, GO:0005932=PMID:12802074} Q8TCX1 Cytoplasmic dynein 2 light intermediate chain 1 protein 20110316 {GO:0005881=ISS, GO:0007368=IEA, GO:0045177=ISS, GO:0031512=ISS, GO:0072372=ISS, GO:0035085=ISS, GO:0005829=TAS, GO:0042384=IEA, GO:0019886=TAS, GO:0003774=IEA, GO:0005858=ISS, GO:0030990=ISS, GO:0005932=ISS} antigen processing and presentation of exogenous peptide antigen via MHC class II, cilium assembly, determination of left/right symmetry apical part of cell, axonemal dynein complex, cilium axoneme, cytoplasmic microtubule, cytosol, intraflagellar transport particle, microtubule basal body, motile primary cilium, primary cilium motor activity colocalizes_with Human UniProtKB:Q7XA07 DYNLL1 IntAct UniProtKB {GO:0005515=PMID:18420585, GO:0072686=PMID:20133940, GO:0030036=PMID:8628263, GO:0005886=Reactome:REACT_1888, GO:0005634=PMID:15891768, GO:0009653=PMID:8628263, GO:0042803=GO_REF:0000019, GO:0005829=Reactome:REACT_120995, GO:0005739=GO_REF:0000039, GO:0019886=Reactome:REACT_121399, GO:0003774=GO_REF:0000037, GO:0005737=PMID:15891768, GO:1900740=Reactome:REACT_1650, GO:0008180=PMID:18850735, GO:0000086=Reactome:REACT_2203, GO:0006810=GO_REF:0000037, GO:0030235=GO_REF:0000019, GO:0007017=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005813=PMID:21399614, GO:0005875=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0019904=GO_REF:0000019, GO:0006915=Reactome:REACT_578, GO:0007292=PMID:8628263, GO:0008022=GO_REF:0000019, GO:0097193=Reactome:REACT_964, GO:0006351=GO_REF:0000037, GO:0042326=PMID:18579519, GO:0016020=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0000776=PMID:20133940, GO:0005868=GO_REF:0000024, GO:0000278=Reactome:REACT_152, GO:0019899=GO_REF:0000019} P63167 Dynein light chain 1, cytoplasmic protein 20130415 {GO:0005515=IPI, GO:0072686=IDA, GO:0030036=TAS, GO:0005886=TAS, GO:0005634=IDA, GO:0009653=TAS, GO:0042803=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0019886=TAS, GO:0003774=IEA, GO:0005737=IDA, GO:1900740=TAS, GO:0008180=IDA, GO:0000086=TAS, GO:0006810=IEA, GO:0030235=IEA, GO:0007017=IEA, GO:0006355=IEA, GO:0005813=IDA, GO:0005875=IEA, GO:0005874=IEA, GO:0019904=IEA, GO:0006915=TAS, GO:0007292=TAS, GO:0008022=IEA, GO:0097193=TAS, GO:0006351=IEA, GO:0042326=IDA, GO:0016020=IEA, GO:0019048=IEA, GO:0000776=IDA, GO:0005868=ISS, GO:0000278=TAS, GO:0019899=IEA} G2/M transition of mitotic cell cycle, actin cytoskeleton organization, anatomical structure morphogenesis, antigen processing and presentation of exogenous peptide antigen via MHC class II, apoptotic process, female gamete generation, intrinsic apoptotic signaling pathway, microtubule-based process, mitotic cell cycle, negative regulation of phosphorylation, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, regulation of transcription, DNA-dependent, transcription, DNA-dependent, transport, virus-host interaction centrosome, cytoplasm, cytoplasmic dynein complex, cytosol, kinetochore, membrane, microtubule, microtubule associated complex, mitochondrion, mitotic spindle, nucleus, plasma membrane, signalosome enzyme binding, motor activity, nitric-oxide synthase regulator activity, protein C-terminus binding, protein binding, protein domain specific binding, protein homodimerization activity Human UniProtKB:P63244 DYNLL2 Reactome UniProtKB {GO:0008092=GO_REF:0000019, GO:0005813=PMID:21399614, GO:0008039=GO_REF:0000019, GO:0005886=Reactome:REACT_1981, GO:0005874=GO_REF:0000037, GO:0006915=Reactome:REACT_578, GO:0016459=GO_REF:0000024, GO:0097193=Reactome:REACT_964, GO:0005829=Reactome:REACT_120995, GO:0019886=Reactome:REACT_121399, GO:0003774=GO_REF:0000037, GO:1900740=Reactome:REACT_2100, GO:0030286=GO_REF:0000037, GO:0006810=GO_REF:0000037, GO:0007017=GO_REF:0000002} Q96FJ2 Dynein light chain 2, cytoplasmic protein 20130213 {GO:0008092=IEA, GO:0005813=IDA, GO:0008039=IEA, GO:0005886=TAS, GO:0005874=IEA, GO:0006915=TAS, GO:0016459=ISS, GO:0097193=TAS, GO:0005829=TAS, GO:0019886=TAS, GO:0003774=IEA, GO:1900740=TAS, GO:0030286=IEA, GO:0006810=IEA, GO:0007017=IEA} antigen processing and presentation of exogenous peptide antigen via MHC class II, apoptotic process, intrinsic apoptotic signaling pathway, microtubule-based process, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, synaptic target recognition, transport centrosome, cytosol, dynein complex, microtubule, myosin complex, plasma membrane cytoskeletal protein binding, motor activity Human DYNLRB1 IntAct UniProtKB {GO:0005515=PMID:10198631, GO:0005813=PMID:21399614, GO:0005737=GO_REF:0000024, GO:0007632=GO_REF:0000024, GO:0005874=GO_REF:0000037, GO:0006810=GO_REF:0000037, GO:0005868=GO_REF:0000024, GO:0003777=PMID:11750132, GO:0007018=PMID:11750132, GO:0042802=GO_REF:0000019} Q9NP97 Dynein light chain roadblock-type 1 protein 20130415 {GO:0005515=IPI, GO:0005813=IDA, GO:0005737=ISS, GO:0007632=ISS, GO:0005874=IEA, GO:0006810=IEA, GO:0005868=ISS, GO:0003777=NAS, GO:0007018=NAS, GO:0042802=IEA} microtubule-based movement, transport, visual behavior centrosome, cytoplasm, cytoplasmic dynein complex, microtubule identical protein binding, microtubule motor activity, protein binding Human UniProtKB:O54918-2 DYNLRB2 UniProtKB UniProtKB {GO:0005874=GO_REF:0000037, GO:0006810=GO_REF:0000037, GO:0005868=GO_REF:0000024, GO:0003777=PMID:11750132, GO:0007018=PMID:11750132} Q8TF09 Dynein light chain roadblock-type 2 protein 20100507 {GO:0005874=IEA, GO:0006810=IEA, GO:0005868=ISS, GO:0003777=NAS, GO:0007018=NAS} microtubule-based movement, transport cytoplasmic dynein complex, microtubule microtubule motor activity Human UniProtKB:Q9DAJ5 DYNLT1 BHF-UCL UniProtKB {GO:0005515=PMID:10644691, GO:0005794=GO_REF:0000039, GO:0019060=PMID:18647839, GO:0005874=GO_REF:0000037, GO:0005819=GO_REF:0000039, GO:0000132=GO_REF:0000024, GO:0046718=GO_REF:0000037, GO:0042802=PMID:17965411, GO:0003774=GO_REF:0000037, GO:0007067=GO_REF:0000037, GO:0008277=GO_REF:0000024, GO:0050768=GO_REF:0000024, GO:0005868=GO_REF:0000024, GO:0051301=GO_REF:0000037} P63172 Dynein light chain Tctex-type 1 protein 20080919 {GO:0005515=IPI, GO:0005794=IEA, GO:0019060=IMP, GO:0005874=IEA, GO:0005819=IEA, GO:0000132=ISS, GO:0046718=IEA, GO:0042802=IPI, GO:0003774=IEA, GO:0007067=IEA, GO:0008277=ISS, GO:0050768=ISS, GO:0005868=ISS, GO:0051301=IEA} cell division, establishment of mitotic spindle orientation, intracellular transport of viral proteins in host cell, mitosis, negative regulation of neurogenesis, regulation of G-protein coupled receptor protein signaling pathway, viral entry into host cell Golgi apparatus, cytoplasmic dynein complex, microtubule, spindle identical protein binding, motor activity, protein binding Human UniProtKB:O14641 DYNLT3 HPA UniProtKB {GO:0005886=GO_REF:0000052, GO:0005874=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0042802=GO_REF:0000019, GO:0007346=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0003774=GO_REF:0000037, GO:0007067=GO_REF:0000037, GO:0006810=GO_REF:0000037, GO:0000777=GO_REF:0000039, GO:0000776=PMID:17289665, GO:0005868=PMID:11425878, GO:0051301=GO_REF:0000037} P51808 Dynein light chain Tctex-type 3 protein 20090616 {GO:0005886=IDA, GO:0005874=IEA, GO:0005634=IEA, GO:0042802=IEA, GO:0007346=ISS, GO:0005737=IDA, GO:0003774=IEA, GO:0007067=IEA, GO:0006810=IEA, GO:0000777=IEA, GO:0000776=IDA, GO:0005868=IDA, GO:0051301=IEA} cell division, mitosis, regulation of mitotic cell cycle, transport condensed chromosome kinetochore, cytoplasm, cytoplasmic dynein complex, kinetochore, microtubule, nucleus, plasma membrane identical protein binding, motor activity Human DYRK1A BHF-UCL UniProtKB {GO:0005515=PMID:20736167, GO:0048156=PMID:20736167, GO:0005634=GO_REF:0000024, GO:0018108=PMID:9748265, GO:0043621=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0007399=PMID:8769099, GO:0090312=GO_REF:0000019, GO:0004672=PMID:8769099, GO:0046777=GO_REF:0000024, GO:0016607=GO_REF:0000024, GO:0004674=PMID:20736167, GO:0018107=PMID:20736167, GO:0030529=GO_REF:0000019, GO:0007623=GO_REF:0000024, GO:0043518=PMID:20736167, GO:0005654=Reactome:REACT_111075, GO:0006468=GO_REF:0000024, GO:0004712=GO_REF:0000003, GO:0004713=GO_REF:0000024, GO:0000278=Reactome:REACT_152, GO:0004715=PMID:9748265} Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A protein 20120312 {GO:0005515=IPI, GO:0048156=ISS, GO:0005634=ISS, GO:0018108=IDA, GO:0043621=ISS, GO:0005524=IEA, GO:0007399=TAS, GO:0090312=IEA, GO:0004672=TAS, GO:0046777=ISS, GO:0016607=ISS, GO:0004674=ISS, GO:0018107=ISS, GO:0030529=IEA, GO:0007623=ISS, GO:0043518=ISS, GO:0005654=TAS, GO:0006468=ISS, GO:0004712=IEA, GO:0004713=ISS, GO:0000278=TAS, GO:0004715=IDA} circadian rhythm, mitotic cell cycle, negative regulation of DNA damage response, signal transduction by p53 class mediator, nervous system development, peptidyl-threonine phosphorylation, peptidyl-tyrosine phosphorylation, positive regulation of protein deacetylation, protein autophosphorylation, protein phosphorylation nuclear speck, nucleoplasm, nucleus, ribonucleoprotein complex ATP binding, non-membrane spanning protein tyrosine kinase activity, protein binding, protein kinase activity, protein self-association, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity, protein tyrosine kinase activity, tau protein binding Human UniProtKB:Q61214 DYRK1B HPA UniProtKB {GO:0005515=PMID:14500717, GO:0004672=PMID:11980910, GO:0004674=GO_REF:0000037, GO:0003713=PMID:11980910, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006468=PMID:11980910, GO:0004712=GO_REF:0000003, GO:0004713=GO_REF:0000037, GO:0045893=PMID:11980910, GO:0005524=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q9Y463 Dual specificity tyrosine-phosphorylation-regulated kinase 1B protein 20101115 {GO:0005515=IPI, GO:0004672=IDA, GO:0004674=IEA, GO:0003713=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0006468=IDA, GO:0004712=IEA, GO:0004713=IEA, GO:0045893=IDA, GO:0005524=IEA, GO:0043231=IDA} positive regulation of transcription, DNA-dependent, protein phosphorylation intracellular membrane-bounded organelle, nucleolus, nucleus ATP binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity, protein tyrosine kinase activity, transcription coactivator activity Human DYRK2 HPA UniProtKB {GO:0043130=PMID:19965871, GO:0000287=PMID:9748265, GO:0030145=PMID:9748265, GO:0045725=PMID:11311121, GO:0051534=PMID:16511445, GO:0005730=GO_REF:0000052, GO:0000151=PMID:19287380, GO:0005634=GO_REF:0000052, GO:0005524=PMID:11311121, GO:0006974=PMID:19965871, GO:0043231=GO_REF:0000052, GO:0007224=PMID:18455992, GO:0042771=PMID:17349958, GO:0005737=GO_REF:0000052, GO:0004674=PMID:11311121, GO:0030529=GO_REF:0000019, GO:0004712=GO_REF:0000003, GO:0006468=PMID:11311121, GO:0004713=PMID:9748265} Q92630 Dual specificity tyrosine-phosphorylation-regulated kinase 2 protein 20101115 {GO:0043130=IDA, GO:0000287=IDA, GO:0030145=IDA, GO:0045725=IDA, GO:0051534=IMP, GO:0005730=IDA, GO:0000151=IDA, GO:0005634=IDA, GO:0005524=IDA, GO:0006974=IEP, GO:0043231=IDA, GO:0007224=IMP, GO:0042771=IDA, GO:0005737=IDA, GO:0004674=IDA, GO:0030529=IEA, GO:0004712=IEA, GO:0006468=IDA, GO:0004713=IDA} intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, negative regulation of NFAT protein import into nucleus, positive regulation of glycogen biosynthetic process, protein phosphorylation, response to DNA damage stimulus, smoothened signaling pathway cytoplasm, intracellular membrane-bounded organelle, nucleolus, nucleus, ribonucleoprotein complex, ubiquitin ligase complex ATP binding, magnesium ion binding, manganese ion binding, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity, protein tyrosine kinase activity, ubiquitin binding Human DYRK3 InterPro UniProtKB {GO:0000287=PMID:10779429, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000037, GO:0030218=PMID:10779429, GO:0005634=PMID:10779429, GO:0006468=PMID:10779429, GO:0004712=GO_REF:0000003, GO:0004713=GO_REF:0000037, GO:0005524=GO_REF:0000002} Q5SY34 Dual-specificity tyrosine-phosphorylation-regulated kinase 3 protein 20130413 {GO:0000287=IDA, GO:0004672=IEA, GO:0004674=IEA, GO:0030218=IDA, GO:0005634=IDA, GO:0006468=IDA, GO:0004712=IEA, GO:0004713=IEA, GO:0005524=IEA} erythrocyte differentiation, protein phosphorylation nucleus ATP binding, magnesium ion binding, protein kinase activity, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity, protein tyrosine kinase activity Human InterPro:IPR000719|InterPro:IPR017441 DYRK4 HPA UniProtKB {GO:0005794=GO_REF:0000052, GO:0004674=GO_REF:0000029, GO:0016301=GO_REF:0000038, GO:0006468=GO_REF:0000029, GO:0004712=GO_REF:0000003, GO:0004713=GO_REF:0000037, GO:0005524=GO_REF:0000029, GO:0046872=GO_REF:0000037, GO:0016772=GO_REF:0000002} Q9NR20 Dual specificity tyrosine-phosphorylation-regulated kinase 4 protein 20100326 {GO:0005794=IDA, GO:0004674=NAS, GO:0016301=IEA, GO:0006468=NAS, GO:0004712=IEA, GO:0004713=IEA, GO:0005524=NAS, GO:0046872=IEA, GO:0016772=IEA} protein phosphorylation Golgi apparatus ATP binding, kinase activity, metal ion binding, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity, protein tyrosine kinase activity, transferase activity, transferring phosphorus-containing groups Human DYSF PINC UniProtKB {GO:0005544=PMID:11959863, GO:0005886=PMID:10496277, GO:0030315=GO_REF:0000019, GO:0001778=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0006906=GO_REF:0000019, GO:0030659=GO_REF:0000039, GO:0030027=GO_REF:0000019} O75923 Dysferlin protein 20030904 {GO:0005544=IMP, GO:0005886=TAS, GO:0030315=IEA, GO:0001778=IEA, GO:0016021=IEA, GO:0006906=IEA, GO:0030659=IEA, GO:0030027=IEA} plasma membrane repair, vesicle fusion T-tubule, cytoplasmic vesicle membrane, integral to membrane, lamellipodium, plasma membrane calcium-dependent phospholipid binding Human DYX1C1 IntAct UniProtKB {GO:0005515=PMID:20562859, GO:0005737=PMID:19423554, GO:0061136=PMID:19423554, GO:0030331=PMID:19423554, GO:0033146=PMID:19423554, GO:0005634=PMID:19423554, GO:0001764=GO_REF:0000024} Q8WXU2 Dyslexia susceptibility 1 candidate gene 1 protein protein 20130415 {GO:0005515=IPI, GO:0005737=IDA, GO:0061136=IDA, GO:0030331=IDA, GO:0033146=IDA, GO:0005634=IDA, GO:0001764=ISS} neuron migration, regulation of intracellular estrogen receptor signaling pathway, regulation of proteasomal protein catabolic process cytoplasm, nucleus estrogen receptor binding, protein binding Human UniProtKB:Q9H0R8 DZANK1 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q9NVP4 Double zinc ribbon and ankyrin repeat-containing protein 1 protein 20130413 {GO:0005622=IEA, GO:0008270=IEA} intracellular zinc ion binding Human InterPro:IPR001876 DZIP1 BHF-UCL UniProtKB {GO:0005515=PMID:15081113, GO:0042384=PMID:19852954, GO:0043234=PMID:15081113, GO:0005737=PMID:15081113, GO:0005814=PMID:19852954, GO:0005634=PMID:15081113, GO:0007275=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0007283=GO_REF:0000037, GO:0007281=PMID:15081113, GO:0036064=PMID:19852954} Q86YF9 Zinc finger protein DZIP1 protein 20120508 {GO:0005515=IPI, GO:0042384=IMP, GO:0043234=NAS, GO:0005737=IDA, GO:0005814=IDA, GO:0005634=IDA, GO:0007275=IEA, GO:0008270=IEA, GO:0007283=IEA, GO:0007281=NAS, GO:0036064=IDA} cilium assembly, germ cell development, multicellular organismal development, spermatogenesis centriole, cilium basal body, cytoplasm, nucleus, protein complex protein binding, zinc ion binding Human DZIP1L BHF-UCL UniProtKB {GO:0042384=PMID:19852954, GO:0005814=PMID:19852954, GO:0008270=GO_REF:0000002, GO:0036064=PMID:19852954} Q8IYY4 Zinc finger protein DZIP1L protein 20120508 {GO:0042384=IMP, GO:0005814=IDA, GO:0008270=IEA, GO:0036064=IDA} cilium assembly centriole, cilium basal body zinc ion binding Human DZIP3 IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0000209=PMID:12538761, GO:0004842=PMID:12538761, GO:0005737=PMID:12538761, GO:0019902=PMID:19389623, GO:0003723=PMID:12538761, GO:0008270=GO_REF:0000002, GO:0031593=PMID:12538761} Q86Y13 E3 ubiquitin-protein ligase DZIP3 protein 20130415 {GO:0005515=IPI, GO:0000209=IDA, GO:0004842=IDA, GO:0005737=IDA, GO:0019902=IDA, GO:0003723=IDA, GO:0008270=IEA, GO:0031593=IDA} protein polyubiquitination cytoplasm RNA binding, phosphatase binding, polyubiquitin binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q9H0E2 E2F1 BHF-UCL UniProtKB {GO:0005515=PMID:20224733, GO:0003700=PMID:11418595, GO:0008283=PMID:10199402, GO:0005634=PMID:12717439, GO:0048146=PMID:20224733, GO:0007283=GO_REF:0000019, GO:2000045=PMID:20224733, GO:0071398=GO_REF:0000019, GO:0000085=Reactome:REACT_1915, GO:0005737=GO_REF:0000019, GO:0000082=Reactome:REACT_1783, GO:0045944=PMID:20224733, GO:0035189=PMID:20224733, GO:0048255=PMID:15766563, GO:0000080=Reactome:REACT_1590, GO:0006355=PMID:12717439, GO:0003714=PMID:10199402, GO:0071456=GO_REF:0000019, GO:0006915=PMID:12717439, GO:0001047=PMID:15735762, GO:0000122=PMID:20224733, GO:0003677=PMID:15073182, GO:0071930=PMID:20224733, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000019, GO:0010628=PMID:15766563, GO:0005654=Reactome:REACT_111167, GO:0030900=GO_REF:0000019, GO:0000077=PMID:12717439, GO:0045893=PMID:20224733, GO:0000278=Reactome:REACT_152, GO:0045892=PMID:20224733, GO:0008134=PMID:16360038} Q01094 Transcription factor E2F1 protein 20110314 {GO:0005515=IPI, GO:0003700=TAS, GO:0008283=TAS, GO:0005634=IDA, GO:0048146=IMP, GO:0007283=IEA, GO:2000045=IMP, GO:0071398=IEA, GO:0000085=TAS, GO:0005737=IEA, GO:0000082=TAS, GO:0045944=IMP, GO:0035189=IDA, GO:0048255=IDA, GO:0000080=TAS, GO:0006355=IDA, GO:0003714=TAS, GO:0071456=IEA, GO:0006915=IMP, GO:0001047=IDA, GO:0000122=IMP, GO:0003677=IDA, GO:0071930=IMP, GO:0006351=IEA, GO:0043565=IEA, GO:0010628=IDA, GO:0005654=TAS, GO:0030900=IEA, GO:0000077=IMP, GO:0045893=IMP, GO:0000278=TAS, GO:0045892=IMP, GO:0008134=IPI} DNA damage checkpoint, G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, G2 phase of mitotic cell cycle, apoptotic process, cell proliferation, cellular response to fatty acid, cellular response to hypoxia, forebrain development, mRNA stabilization, mitotic cell cycle, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription involved in G1/S phase of mitotic cell cycle, negative regulation of transcription, DNA-dependent, positive regulation of fibroblast proliferation, positive regulation of gene expression, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of G1/S transition of mitotic cell cycle, regulation of transcription, DNA-dependent, spermatogenesis, transcription, DNA-dependent Rb-E2F complex, cytoplasm, nucleoplasm, nucleus DNA binding, core promoter binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity, transcription factor binding Human E2F2 Reactome UniProtKB {GO:0005515=PMID:16360038, GO:0005667=GO_REF:0000002, GO:0006367=PMID:8246996, GO:0003700=GO_REF:0000019, GO:0051726=GO_REF:0000019, GO:0006915=GO_REF:0000019, GO:0005654=Reactome:REACT_1882, GO:0001047=PMID:15735762, GO:0000278=Reactome:REACT_152, GO:0000080=Reactome:REACT_1590, GO:0003677=PMID:8246995, GO:0008134=PMID:16360038} Q14209 Transcription factor E2F2 protein 20130213 {GO:0005515=IPI, GO:0005667=IEA, GO:0006367=TAS, GO:0003700=IEA, GO:0051726=IEA, GO:0006915=IEA, GO:0005654=TAS, GO:0001047=IDA, GO:0000278=TAS, GO:0000080=TAS, GO:0003677=TAS, GO:0008134=IPI} G1 phase of mitotic cell cycle, apoptotic process, mitotic cell cycle, regulation of cell cycle, transcription initiation from RNA polymerase II promoter nucleoplasm, transcription factor complex DNA binding, core promoter binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human E2F3 Reactome UniProtKB {GO:0005515=PMID:17438371, GO:0000085=Reactome:REACT_1915, GO:0005667=GO_REF:0000002, GO:0008284=GO_REF:0000019, GO:0006367=PMID:8246996, GO:0003700=GO_REF:0000019, GO:0005654=Reactome:REACT_9023, GO:0001047=PMID:15735762, GO:0000278=Reactome:REACT_152, GO:0000080=Reactome:REACT_1590, GO:0045893=GO_REF:0000019} O00716 Transcription factor E2F3 protein 20130213 {GO:0005515=IPI, GO:0000085=TAS, GO:0005667=IEA, GO:0008284=IEA, GO:0006367=TAS, GO:0003700=IEA, GO:0005654=TAS, GO:0001047=IDA, GO:0000278=TAS, GO:0000080=TAS, GO:0045893=IEA} G1 phase of mitotic cell cycle, G2 phase of mitotic cell cycle, mitotic cell cycle, positive regulation of cell proliferation, positive regulation of transcription, DNA-dependent, transcription initiation from RNA polymerase II promoter nucleoplasm, transcription factor complex core promoter binding, protein binding, sequence-specific DNA binding transcription factor activity Human E2F4 Reactome UniProtKB {GO:0005515=PMID:22002537, GO:0010467=Reactome:REACT_71, GO:0005667=GO_REF:0000002, GO:0008361=GO_REF:0000019, GO:0006367=Reactome:REACT_12627, GO:0003700=PMID:11418595, GO:0008015=GO_REF:0000019, GO:0019904=PMID:16360038, GO:0003677=PMID:11418595, GO:0006351=Reactome:REACT_121061, GO:0006884=GO_REF:0000019, GO:0042384=GO_REF:0000019, GO:0000083=GO_REF:0000019, GO:0045944=Reactome:REACT_120734, GO:0042127=GO_REF:0000019, GO:0002064=GO_REF:0000019, GO:0009887=GO_REF:0000019, GO:0007179=Reactome:REACT_6844, GO:0005654=Reactome:REACT_121097, GO:0000278=Reactome:REACT_152, GO:0000080=Reactome:REACT_1590, GO:0008134=PMID:16360038} Q16254 Transcription factor E2F4 protein 20130301 {GO:0005515=IPI, GO:0010467=TAS, GO:0005667=IEA, GO:0008361=IEA, GO:0006367=TAS, GO:0003700=IDA, GO:0008015=IEA, GO:0019904=IPI, GO:0003677=IMP, GO:0006351=TAS, GO:0006884=IEA, GO:0042384=IEA, GO:0000083=IEA, GO:0045944=TAS, GO:0042127=IEA, GO:0002064=IEA, GO:0009887=IEA, GO:0007179=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000080=TAS, GO:0008134=IPI} G1 phase of mitotic cell cycle, blood circulation, cell volume homeostasis, cilium assembly, epithelial cell development, gene expression, mitotic cell cycle, organ morphogenesis, positive regulation of transcription from RNA polymerase II promoter, regulation of cell proliferation, regulation of cell size, regulation of transcription involved in G1/S phase of mitotic cell cycle, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway nucleoplasm, transcription factor complex DNA binding, protein binding, protein domain specific binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human E2F5 Reactome UniProtKB {GO:0005515=PMID:16360038, GO:0010467=Reactome:REACT_71, GO:0005667=GO_REF:0000002, GO:0003700=GO_REF:0000019, GO:0006367=Reactome:REACT_12627, GO:0003677=GO_REF:0000037, GO:0006351=Reactome:REACT_121061, GO:0005737=GO_REF:0000019, GO:0045944=Reactome:REACT_120734, GO:0009887=GO_REF:0000019, GO:0005654=Reactome:REACT_121097, GO:0007179=Reactome:REACT_6844, GO:0000080=Reactome:REACT_1590, GO:0000278=Reactome:REACT_152, GO:0008134=PMID:16360038} Q15329 Transcription factor E2F5 protein 20130301 {GO:0005515=IPI, GO:0010467=TAS, GO:0005667=IEA, GO:0003700=IEA, GO:0006367=TAS, GO:0003677=IEA, GO:0006351=TAS, GO:0005737=IEA, GO:0045944=TAS, GO:0009887=IEA, GO:0005654=TAS, GO:0007179=TAS, GO:0000080=TAS, GO:0000278=TAS, GO:0008134=IPI} G1 phase of mitotic cell cycle, gene expression, mitotic cell cycle, organ morphogenesis, positive regulation of transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway cytoplasm, nucleoplasm, transcription factor complex DNA binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human E2F6 PINC UniProtKB {GO:0005667=GO_REF:0000002, GO:0000083=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0003714=PMID:9501179, GO:0071339=PMID:15960975, GO:0000122=PMID:9501179, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037} O75461 Transcription factor E2F6 protein 20030904 {GO:0005667=IEA, GO:0000083=IEA, GO:0003700=IEA, GO:0003714=TAS, GO:0071339=IDA, GO:0000122=TAS, GO:0003677=IEA, GO:0006351=IEA} negative regulation of transcription from RNA polymerase II promoter, regulation of transcription involved in G1/S phase of mitotic cell cycle, transcription, DNA-dependent MLL1 complex, transcription factor complex DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human E2F7 IntAct UniProtKB {GO:0005667=GO_REF:0000002, GO:0032466=GO_REF:0000024, GO:0003700=PMID:22802528, GO:0008285=PMID:22802528, GO:0030330=PMID:22802528, GO:0003714=GO_REF:0000024, GO:0060707=GO_REF:0000024, GO:0032877=GO_REF:0000024, GO:2000134=GO_REF:0000024, GO:0005634=GO_REF:0000019, GO:0002040=PMID:22903062, GO:0001047=PMID:22903062, GO:0000122=PMID:22802528, GO:0001890=GO_REF:0000024, GO:0003677=GO_REF:0000038, GO:0006351=GO_REF:0000037, GO:0071930=PMID:22802528, GO:0042802=PMID:15133492, GO:0045944=PMID:22903062, GO:0060718=GO_REF:0000024, GO:0070365=GO_REF:0000024} Q96AV8 Transcription factor E2F7 protein 20130415 {GO:0005667=IEA, GO:0032466=ISS, GO:0003700=IDA, GO:0008285=IMP, GO:0030330=IDA, GO:0003714=ISS, GO:0060707=ISS, GO:0032877=ISS, GO:2000134=ISS, GO:0005634=IEA, GO:0002040=IMP, GO:0001047=IDA, GO:0000122=IDA, GO:0001890=ISS, GO:0003677=IEA, GO:0006351=IEA, GO:0071930=IDA, GO:0042802=IPI, GO:0045944=IMP, GO:0060718=ISS, GO:0070365=ISS} DNA damage response, signal transduction by p53 class mediator, chorionic trophoblast cell differentiation, hepatocyte differentiation, negative regulation of G1/S transition of mitotic cell cycle, negative regulation of cell proliferation, negative regulation of cytokinesis, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription involved in G1/S phase of mitotic cell cycle, placenta development, positive regulation of DNA endoreduplication, positive regulation of transcription from RNA polymerase II promoter, sprouting angiogenesis, transcription, DNA-dependent, trophoblast giant cell differentiation nucleus, transcription factor complex DNA binding, core promoter binding, identical protein binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human UniProtKB:Q96AV8 E2F8 UniProtKB UniProtKB {GO:0005667=GO_REF:0000002, GO:0032466=GO_REF:0000024, GO:0003700=GO_REF:0000002, GO:0008283=GO_REF:0000019, GO:0003714=GO_REF:0000024, GO:0060707=GO_REF:0000024, GO:0032877=GO_REF:0000024, GO:0005634=GO_REF:0000019, GO:0001047=PMID:22903062, GO:0002040=PMID:22903062, GO:0000122=GO_REF:0000024, GO:0001890=GO_REF:0000024, GO:0003677=GO_REF:0000038, GO:0006351=GO_REF:0000038, GO:0042803=GO_REF:0000019, GO:0045944=PMID:22903062, GO:0033301=GO_REF:0000024, GO:0060718=GO_REF:0000024, GO:0070365=GO_REF:0000024} E9PP48 Transcription factor E2F8 protein 20130413 {GO:0005667=IEA, GO:0032466=ISS, GO:0003700=IEA, GO:0008283=IEA, GO:0003714=ISS, GO:0060707=ISS, GO:0032877=ISS, GO:0005634=IEA, GO:0001047=IDA, GO:0002040=IMP, GO:0000122=ISS, GO:0001890=ISS, GO:0003677=IEA, GO:0006351=IEA, GO:0042803=IEA, GO:0045944=IMP, GO:0033301=ISS, GO:0060718=ISS, GO:0070365=ISS} cell cycle comprising mitosis without cytokinesis, cell proliferation, chorionic trophoblast cell differentiation, hepatocyte differentiation, negative regulation of cytokinesis, negative regulation of transcription from RNA polymerase II promoter, placenta development, positive regulation of DNA endoreduplication, positive regulation of transcription from RNA polymerase II promoter, sprouting angiogenesis, transcription, DNA-dependent, trophoblast giant cell differentiation nucleus, transcription factor complex DNA binding, core promoter binding, protein homodimerization activity, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human UniProtKB-KW:KW-0804 E4F1 IntAct UniProtKB {GO:0005515=PMID:14729613, GO:0016567=GO_REF:0000041, GO:0003700=PMID:9121437, GO:0035497=PMID:14645522, GO:0008283=PMID:10869426, GO:0016874=GO_REF:0000037, GO:0009790=GO_REF:0000019, GO:0010564=PMID:14645522, GO:0009794=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0003714=PMID:10869426, GO:0003713=PMID:9121437, GO:0005819=GO_REF:0000019, GO:0000122=PMID:14645522, GO:0003676=GO_REF:0000002, GO:0003677=PMID:10869426, GO:0006351=GO_REF:0000037, GO:0006260=GO_REF:0000019, GO:0071850=PMID:14645522, GO:0007067=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0005654=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0040008=GO_REF:0000037, GO:0051301=GO_REF:0000037} Q66K89 Transcription factor E4F1 protein 20130415 {GO:0005515=IPI, GO:0016567=IEA, GO:0003700=TAS, GO:0035497=IDA, GO:0008283=TAS, GO:0016874=IEA, GO:0009790=IEA, GO:0010564=IDA, GO:0009794=IEA, GO:0005737=IEA, GO:0003714=TAS, GO:0003713=TAS, GO:0005819=IEA, GO:0000122=IDA, GO:0003676=IEA, GO:0003677=TAS, GO:0006351=IEA, GO:0006260=IEA, GO:0071850=TAS, GO:0007067=IEA, GO:0019048=IEA, GO:0005654=IEA, GO:0008270=IEA, GO:0040008=IEA, GO:0051301=IEA} DNA replication, cell division, cell proliferation, embryo development, mitosis, mitotic cell cycle arrest, negative regulation of transcription from RNA polymerase II promoter, protein ubiquitination, regulation of cell cycle process, regulation of growth, regulation of mitotic cell cycle, embryonic, transcription, DNA-dependent, virus-host interaction cytoplasm, nucleoplasm, spindle DNA binding, cAMP response element binding, ligase activity, nucleic acid binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, transcription corepressor activity, zinc ion binding Human UniProtKB:Q9NS23-2 EAF1 IntAct UniProtKB {GO:0005515=PMID:21729782, GO:0006355=GO_REF:0000037, GO:0015030=GO_REF:0000039, GO:0016607=GO_REF:0000039, GO:0032783=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q96JC9 ELL-associated factor 1 protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0015030=IEA, GO:0016607=IEA, GO:0032783=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent Cajal body, ELL-EAF complex, nuclear speck protein binding Human UniProtKB:O95402 EAF2 HPA UniProtKB {GO:0005515=PMID:17395368, GO:0060770=GO_REF:0000019, GO:0030308=GO_REF:0000019, GO:0006355=GO_REF:0000002, GO:0016607=GO_REF:0000039, GO:0032783=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0006917=GO_REF:0000019, GO:0045893=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q96CJ1 ELL-associated factor 2 protein 20100326 {GO:0005515=IPI, GO:0060770=IEA, GO:0030308=IEA, GO:0006355=IEA, GO:0016607=IEA, GO:0032783=IEA, GO:0005730=IDA, GO:0006915=IEA, GO:0005634=IDA, GO:0006917=IEA, GO:0045893=IEA, GO:0006351=IEA} apoptotic process, induction of apoptosis, negative regulation of cell growth, negative regulation of epithelial cell proliferation involved in prostate gland development, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent ELL-EAF complex, nuclear speck, nucleolus, nucleus protein binding NOT Human EAPP HPA UniProtKB {GO:0008284=PMID:15716352, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0032968=PMID:15716352, GO:0005634=GO_REF:0000052, GO:0034244=PMID:15716352} Q56P03 E2F-associated phosphoprotein protein 20110516 {GO:0008284=IDA, GO:0005737=IDA, GO:0005794=IDA, GO:0032968=IDA, GO:0005634=IDA, GO:0034244=IDA} negative regulation of transcription elongation from RNA polymerase II promoter, positive regulation of cell proliferation, positive regulation of transcription elongation from RNA polymerase II promoter Golgi apparatus, cytoplasm, nucleus Human EARS2 Reactome UniProtKB {GO:0005739=PMID:19805282, GO:0010467=Reactome:REACT_71, GO:0050561=PMID:19805282, GO:0005737=GO_REF:0000002, GO:0070127=PMID:19805282, GO:0006424=PMID:19805282, GO:0000049=GO_REF:0000002, GO:0004818=PMID:19805282, GO:0005759=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0006418=Reactome:REACT_15482} Q5JPH6 Probable glutamate--tRNA ligase, mitochondrial protein 20130301 {GO:0005739=IDA, GO:0010467=TAS, GO:0050561=IDA, GO:0005737=IEA, GO:0070127=IDA, GO:0006424=IDA, GO:0000049=IEA, GO:0004818=IDA, GO:0005759=IEA, GO:0005524=IEA, GO:0006418=TAS} gene expression, glutamyl-tRNA aminoacylation, tRNA aminoacylation for mitochondrial protein translation, tRNA aminoacylation for protein translation cytoplasm, mitochondrial matrix, mitochondrion ATP binding, glutamate-tRNA ligase activity, glutamate-tRNA(Gln) ligase activity, tRNA binding Human EBAG9 HPA UniProtKB {GO:0016505=PMID:10426319, GO:0005794=GO_REF:0000052, GO:0000139=GO_REF:0000039, GO:0005886=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0016021=GO_REF:0000029, GO:0030141=GO_REF:0000019, GO:0001558=PMID:10426319, GO:0005925=GO_REF:0000052} O00559 Receptor-binding cancer antigen expressed on SiSo cells protein 20101115 {GO:0016505=NAS, GO:0005794=IDA, GO:0000139=IEA, GO:0005886=IDA, GO:0006915=IEA, GO:0016021=NAS, GO:0030141=IEA, GO:0001558=NAS, GO:0005925=IDA} apoptotic process, regulation of cell growth Golgi apparatus, Golgi membrane, focal adhesion, integral to membrane, plasma membrane, secretory granule apoptotic protease activator activity Human EBF1 UniProtKB UniProtKB {GO:0006355=GO_REF:0000038, GO:0003700=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0045893=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9UH73 Transcription factor COE1 protein 20130413 {GO:0006355=IEA, GO:0003700=IEA, GO:0046983=IEA, GO:0005634=IEA, GO:0007275=IEA, GO:0045893=IEA, GO:0003677=IEA, GO:0046872=IEA, GO:0006351=IEA} multicellular organismal development, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, metal ion binding, protein dimerization activity, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0191 EBF2 UniProtKB UniProtKB {GO:0006355=GO_REF:0000002, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0045893=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9HAK2 Transcription factor COE2 protein 20130413 {GO:0006355=IEA, GO:0046983=IEA, GO:0005634=IEA, GO:0007275=IEA, GO:0045893=IEA, GO:0003677=IEA, GO:0046872=IEA, GO:0006351=IEA} multicellular organismal development, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, metal ion binding, protein dimerization activity Human UniProtKB-SubCell:SL-0191 EBF3 UniProtKB UniProtKB {GO:0006355=GO_REF:0000002, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0045893=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9H4W6 Transcription factor COE3 protein 20130413 {GO:0006355=IEA, GO:0046983=IEA, GO:0005634=IEA, GO:0007275=IEA, GO:0045893=IEA, GO:0003677=IEA, GO:0046872=IEA, GO:0006351=IEA} multicellular organismal development, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, metal ion binding, protein dimerization activity Human UniProtKB-SubCell:SL-0191 EBF4 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0008134=GO_REF:0000019} Q9BQW3 Transcription factor COE4 protein 20130413 {GO:0006355=IEA, GO:0046983=IEA, GO:0005634=IEA, GO:0007275=IEA, GO:0003677=IEA, GO:0046872=IEA, GO:0006351=IEA, GO:0008134=IEA} multicellular organismal development, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, metal ion binding, protein dimerization activity, transcription factor binding Human UniProtKB-SubCell:SL-0191 EBI3 GOC UniProtKB {GO:0004896=PMID:9342359, GO:0005886=PMID:8551575, GO:0006959=PMID:8551575, GO:0045078=PMID:14743498, GO:0019221=PMID:9342359, GO:0046641=PMID:14743498, GO:0045523=GO_REF:0000019, GO:0042088=PMID:14743498, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037} Q14213 Interleukin-27 subunit beta protein 20130413 {GO:0004896=IPI, GO:0005886=TAS, GO:0006959=TAS, GO:0045078=TAS, GO:0019221=IPI, GO:0046641=TAS, GO:0045523=IEA, GO:0042088=TAS, GO:0005615=IEA, GO:0005125=IEA} T-helper 1 type immune response, cytokine-mediated signaling pathway, humoral immune response, positive regulation of alpha-beta T cell proliferation, positive regulation of interferon-gamma biosynthetic process extracellular space, plasma membrane cytokine activity, cytokine receptor activity, interleukin-27 receptor binding Human UniProtKB:P29459 EBLN2 null null {} null null null null {} null null null EBNA1BP2 HPA UniProtKB {GO:0016020=PMID:7596406, GO:0042254=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q99848 Probable rRNA-processing protein EBP2 protein 20101115 {GO:0016020=TAS, GO:0042254=IEA, GO:0005730=IDA, GO:0005634=IDA} ribosome biogenesis membrane, nucleolus, nucleus Human EBP GOC UniProtKB {GO:0030097=GO_REF:0000019, GO:0006695=Reactome:REACT_9405, GO:0004769=PMID:10391219, GO:0000247=GO_REF:0000019, GO:0005783=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0047750=GO_REF:0000003, GO:0001501=PMID:10391219, GO:0005887=PMID:7706302, GO:0006855=PMID:7706302, GO:0005789=Reactome:REACT_9999, GO:0016126=GO_REF:0000019, GO:0016021=GO_REF:0000002, GO:0015238=PMID:7706302, GO:0004888=PMID:7706302, GO:0008203=PMID:10391219} Q15125 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase protein 20130413 {GO:0030097=IEA, GO:0006695=TAS, GO:0004769=TAS, GO:0000247=IEA, GO:0005783=IDA, GO:0044281=TAS, GO:0047750=IEA, GO:0001501=TAS, GO:0005887=TAS, GO:0006855=TAS, GO:0005789=TAS, GO:0016126=IEA, GO:0016021=IEA, GO:0015238=TAS, GO:0004888=TAS, GO:0008203=TAS} cholesterol biosynthetic process, cholesterol metabolic process, drug transmembrane transport, hemopoiesis, skeletal system development, small molecule metabolic process, sterol biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, integral to plasma membrane C-8 sterol isomerase activity, cholestenol delta-isomerase activity, drug transmembrane transporter activity, steroid delta-isomerase activity, transmembrane signaling receptor activity Human EBPL UniProtKB UniProtKB {GO:0005783=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0016125=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0047750=GO_REF:0000002} Q9BY08 Emopamil-binding protein-like protein 20130413 {GO:0005783=IEA, GO:0005789=IEA, GO:0016125=IEA, GO:0016021=IEA, GO:0047750=IEA} sterol metabolic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane cholestenol delta-isomerase activity Human UniProtKB-SubCell:SL-0097 ECD PINC UniProtKB {GO:0006110=PMID:9928932, GO:0005737=GO_REF:0000039, GO:0006355=GO_REF:0000037, GO:0006366=PMID:9928932, GO:0008283=GO_REF:0000019, GO:0003713=PMID:9928932, GO:0005634=GO_REF:0000039, GO:2000045=GO_REF:0000019} O95905 Protein SGT1 protein 20030904 {GO:0006110=TAS, GO:0005737=IEA, GO:0006355=IEA, GO:0006366=TAS, GO:0008283=IEA, GO:0003713=TAS, GO:0005634=IEA, GO:2000045=IEA} cell proliferation, regulation of G1/S transition of mitotic cell cycle, regulation of glycolysis, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter cytoplasm, nucleus transcription coactivator activity Human ECE1 BHF-UCL UniProtKB {GO:0048471=PMID:9710124, GO:0034959=PMID:7805846, GO:0010814=PMID:18039931, GO:0010815=PMID:18039931, GO:0010816=PMID:18039931, GO:0042803=PMID:7805846, GO:0046872=GO_REF:0000037, GO:0043583=PMID:9915973, GO:0019229=PMID:7805846, GO:0007507=PMID:9915973, GO:0016486=PMID:7864876, GO:0016485=PMID:7805846, GO:0006508=GO_REF:0000037, GO:0001921=PMID:18039931, GO:0003100=PMID:7805846, GO:0033093=PMID:9710124, GO:0031982=PMID:9449382, GO:0060037=GO_REF:0000019, GO:0004175=PMID:18039931, GO:0031302=PMID:18039931, GO:0042447=PMID:7864876, GO:0016021=PMID:7805846, GO:0017046=PMID:7864876, GO:0004222=PMID:8062389, GO:0009897=PMID:9449382, GO:0042733=PMID:9915973, GO:0005768=PMID:18039931} P42892 Endothelin-converting enzyme 1 protein 20080903 {GO:0048471=IDA, GO:0034959=IDA, GO:0010814=IDA, GO:0010815=IDA, GO:0010816=IDA, GO:0042803=IPI, GO:0046872=IEA, GO:0043583=IMP, GO:0019229=IC, GO:0007507=IMP, GO:0016486=IDA, GO:0016485=IDA, GO:0006508=IEA, GO:0001921=IMP, GO:0003100=IC, GO:0033093=IDA, GO:0031982=ISS, GO:0060037=IEA, GO:0004175=IDA, GO:0031302=TAS, GO:0042447=IDA, GO:0016021=IDA, GO:0017046=IC, GO:0004222=ISS, GO:0009897=IDA, GO:0042733=IMP, GO:0005768=IDA} bradykinin catabolic process, calcitonin catabolic process, ear development, embryonic digit morphogenesis, endothelin maturation, heart development, hormone catabolic process, peptide hormone processing, pharyngeal system development, positive regulation of receptor recycling, protein processing, proteolysis, regulation of systemic arterial blood pressure by endothelin, regulation of vasoconstriction, substance P catabolic process Weibel-Palade body, endosome, external side of plasma membrane, integral to membrane, intrinsic to endosome membrane, perinuclear region of cytoplasm, vesicle endopeptidase activity, metal ion binding, metalloendopeptidase activity, peptide hormone binding, protein homodimerization activity Human UniProtKB:P42893 ECE2 UniProtKB UniProtKB {GO:0007507=GO_REF:0000024, GO:0016486=PMID:11718899, GO:0000139=GO_REF:0000039, GO:0007420=GO_REF:0000024, GO:0008168=GO_REF:0000037, GO:0007267=PMID:11718899, GO:0010002=GO_REF:0000024, GO:0006508=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0004222=PMID:11718899, GO:0030659=PMID:11718899, GO:0046872=GO_REF:0000037} O60344 Endothelin-converting enzyme 2 protein 20030818 {GO:0007507=ISS, GO:0016486=IDA, GO:0000139=IEA, GO:0007420=ISS, GO:0008168=IEA, GO:0007267=TAS, GO:0010002=ISS, GO:0006508=IEA, GO:0016021=IEA, GO:0004222=IDA, GO:0030659=IDA, GO:0046872=IEA} brain development, cardioblast differentiation, cell-cell signaling, heart development, peptide hormone processing, proteolysis Golgi membrane, cytoplasmic vesicle membrane, integral to membrane metal ion binding, metalloendopeptidase activity, methyltransferase activity Human ECEL1 PINC UniProtKB {GO:0007218=PMID:9931490, GO:0005887=PMID:9931490, GO:0006508=GO_REF:0000037, GO:0004222=GO_REF:0000019, GO:0008237=PMID:9931490, GO:0046872=GO_REF:0000037} O95672 Endothelin-converting enzyme-like 1 protein 20030904 {GO:0007218=TAS, GO:0005887=TAS, GO:0006508=IEA, GO:0004222=IEA, GO:0008237=TAS, GO:0046872=IEA} neuropeptide signaling pathway, proteolysis integral to plasma membrane metal ion binding, metalloendopeptidase activity, metallopeptidase activity Human ECH1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005515=PMID:21988832, GO:0006635=GO_REF:0000041, GO:0005102=PMID:20178365, GO:0016853=GO_REF:0000037, GO:0003824=GO_REF:0000002, GO:0005777=PMID:7558027} Q13011 Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial protein 20101115 {GO:0005739=IDA, GO:0005515=IPI, GO:0006635=IEA, GO:0005102=IPI, GO:0016853=IEA, GO:0003824=IEA, GO:0005777=NAS} fatty acid beta-oxidation mitochondrion, peroxisome catalytic activity, isomerase activity, protein binding, receptor binding Human ECHDC1 UniProtKB UniProtKB {GO:0016831=GO_REF:0000024, GO:0004492=GO_REF:0000003, GO:0003824=GO_REF:0000002, GO:0005829=GO_REF:0000024} Q9NTX5 Ethylmalonyl-CoA decarboxylase protein 20120127 {GO:0016831=ISS, GO:0004492=IEA, GO:0003824=IEA, GO:0005829=ISS} cytosol carboxy-lyase activity, catalytic activity, methylmalonyl-CoA decarboxylase activity Human UniProtKB:Q9D9V3 ECHDC2 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0006631=GO_REF:0000037, GO:0003824=GO_REF:0000002, GO:0016829=GO_REF:0000037} Q86YB7 Enoyl-CoA hydratase domain-containing protein 2, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0006631=IEA, GO:0003824=IEA, GO:0016829=IEA} fatty acid metabolic process mitochondrion catalytic activity, lyase activity Human UniProtKB-SubCell:SL-0173 ECHS1 HPA UniProtKB {GO:0005515=PMID:14557246, GO:0005739=GO_REF:0000052, GO:0006635=Reactome:REACT_1473, GO:0005759=Reactome:REACT_583, GO:0044281=Reactome:REACT_111217, GO:0004300=Reactome:REACT_583, GO:0044255=Reactome:REACT_22279} P30084 Enoyl-CoA hydratase, mitochondrial protein 20100326 {GO:0005515=IPI, GO:0005739=IDA, GO:0006635=TAS, GO:0005759=TAS, GO:0044281=TAS, GO:0004300=TAS, GO:0044255=TAS} cellular lipid metabolic process, fatty acid beta-oxidation, small molecule metabolic process mitochondrial matrix, mitochondrion enoyl-CoA hydratase activity, protein binding Human ECI1 Reactome UniProtKB {GO:0016860=Reactome:REACT_1445, GO:0006635=Reactome:REACT_1473, GO:0004165=Reactome:REACT_588, GO:0005759=Reactome:REACT_1445, GO:0005743=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0044255=Reactome:REACT_22279} P42126 Enoyl-CoA delta isomerase 1, mitochondrial protein 20130213 {GO:0016860=TAS, GO:0006635=TAS, GO:0004165=TAS, GO:0005759=TAS, GO:0005743=IEA, GO:0044281=TAS, GO:0003824=IEA, GO:0044255=TAS} cellular lipid metabolic process, fatty acid beta-oxidation, small molecule metabolic process mitochondrial inner membrane, mitochondrial matrix catalytic activity, dodecenoyl-CoA delta-isomerase activity, intramolecular oxidoreductase activity Human ECI2 HPA UniProtKB {GO:0005739=GO_REF:0000054, GO:0005782=GO_REF:0000039, GO:0004165=GO_REF:0000003, GO:0005102=PMID:20178365, GO:0003824=GO_REF:0000002, GO:0000062=GO_REF:0000002, GO:0043231=GO_REF:0000052} O75521 Enoyl-CoA delta isomerase 2, mitochondrial protein 20100326 {GO:0005739=IDA, GO:0005782=IEA, GO:0004165=IEA, GO:0005102=IPI, GO:0003824=IEA, GO:0000062=IEA, GO:0043231=IDA} intracellular membrane-bounded organelle, mitochondrion, peroxisomal matrix catalytic activity, dodecenoyl-CoA delta-isomerase activity, fatty-acyl-CoA binding, receptor binding Human ECM1 GOC UniProtKB {GO:0005515=PMID:19275936, GO:2000404=GO_REF:0000019, GO:0005134=GO_REF:0000019, GO:0006357=GO_REF:0000019, GO:0010466=PMID:16512877, GO:0005578=PMID:9367673, GO:0001525=GO_REF:0000037, GO:0030502=PMID:11165938, GO:0002020=PMID:16512877, GO:0008022=PMID:12604605, GO:0031214=GO_REF:0000037, GO:0005615=GO_REF:0000019, GO:0045766=PMID:11292659, GO:0031012=PMID:20870722, GO:0007165=PMID:12761501, GO:0006954=GO_REF:0000019, GO:0001960=GO_REF:0000019, GO:0001938=PMID:11292659, GO:0001503=GO_REF:0000037, GO:0002828=GO_REF:0000019, GO:0043236=PMID:19275936, GO:0004871=PMID:12761501, GO:0019899=PMID:20870722, GO:0043123=PMID:12761501} Q16610 Extracellular matrix protein 1 protein 20130413 {GO:0005515=IPI, GO:2000404=IEA, GO:0005134=IEA, GO:0006357=IEA, GO:0010466=IDA, GO:0005578=NAS, GO:0001525=IEA, GO:0030502=IDA, GO:0002020=IPI, GO:0008022=IPI, GO:0031214=IEA, GO:0005615=IEA, GO:0045766=IDA, GO:0031012=IDA, GO:0007165=IMP, GO:0006954=IEA, GO:0001960=IEA, GO:0001938=IDA, GO:0001503=IEA, GO:0002828=IEA, GO:0043236=IPI, GO:0004871=IMP, GO:0019899=IPI, GO:0043123=IMP} angiogenesis, biomineral tissue development, inflammatory response, negative regulation of bone mineralization, negative regulation of cytokine-mediated signaling pathway, negative regulation of peptidase activity, ossification, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of angiogenesis, positive regulation of endothelial cell proliferation, regulation of T cell migration, regulation of transcription from RNA polymerase II promoter, regulation of type 2 immune response, signal transduction extracellular matrix, extracellular space, proteinaceous extracellular matrix enzyme binding, interleukin-2 receptor binding, laminin binding, protease binding, protein C-terminus binding, protein binding, signal transducer activity Human ECSCR UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0006935=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0001525=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q19T08 Endothelial cell-specific chemotaxis regulator protein 20130413 {GO:0005886=IEA, GO:0006935=IEA, GO:0016021=IEA, GO:0001525=IEA, GO:0030154=IEA} angiogenesis, cell differentiation, chemotaxis integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 ECSIT HPA UniProtKB {GO:0005515=PMID:21163940, GO:0051341=PMID:17344420, GO:0005667=GO_REF:0000019, GO:0001707=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0030509=GO_REF:0000019, GO:0005739=PMID:17344420, GO:0005737=GO_REF:0000052, GO:0045087=GO_REF:0000037, GO:0016651=PMID:17344420, GO:0004871=GO_REF:0000019} Q9BQ95 Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial protein 20111111 {GO:0005515=IPI, GO:0051341=IDA, GO:0005667=IEA, GO:0001707=IEA, GO:0003700=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0030509=IEA, GO:0005739=IDA, GO:0005737=IDA, GO:0045087=IEA, GO:0016651=IDA, GO:0004871=IEA} BMP signaling pathway, innate immune response, mesoderm formation, regulation of oxidoreductase activity cytoplasm, mitochondrion, nucleolus, nucleus, transcription factor complex oxidoreductase activity, acting on NAD(P)H, protein binding, sequence-specific DNA binding transcription factor activity, signal transducer activity Human ECT2 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0045859=PMID:15254234, GO:0072686=PMID:20047078, GO:0070301=PMID:21373644, GO:0007264=Reactome:REACT_11044, GO:0035023=GO_REF:0000002, GO:0005634=PMID:20047078, GO:0015031=GO_REF:0000037, GO:0032154=PMID:20047078, GO:0042803=PMID:15545273, GO:0005829=Reactome:REACT_19216, GO:0035556=GO_REF:0000002, GO:0005085=GO_REF:0000002, GO:0032147=PMID:15254234, GO:0000910=GO_REF:0000002, GO:0005737=PMID:20047078, GO:0005543=GO_REF:0000002, GO:0070830=PMID:15254234, GO:0005911=PMID:15254234, GO:0043089=PMID:19617897, GO:0071277=PMID:15254234, GO:0051260=PMID:15545273, GO:0004871=PMID:12761501, GO:0005089=PMID:12761501, GO:0043123=PMID:12761501, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0043065=PMID:21373644, GO:0051988=PMID:15642749, GO:0006915=Reactome:REACT_13638, GO:0030496=PMID:15545273, GO:0032862=PMID:19617897, GO:0032863=PMID:19617897, GO:0097190=Reactome:REACT_13720, GO:0071479=PMID:21373644, GO:0000902=GO_REF:0000019, GO:0032321=PMID:21373644, GO:0045666=GO_REF:0000024, GO:0042307=GO_REF:0000024, GO:0017048=GO_REF:0000019, GO:0097149=PMID:16236794, GO:0005923=PMID:15254234, GO:0005096=PMID:15642749} Q9H8V3 Protein ECT2 protein 20130415 {GO:0005515=IPI, GO:0045859=IDA, GO:0072686=IDA, GO:0070301=IDA, GO:0007264=TAS, GO:0035023=IEA, GO:0005634=IDA, GO:0015031=IEA, GO:0032154=IDA, GO:0042803=IDA, GO:0005829=TAS, GO:0035556=IEA, GO:0005085=IEA, GO:0032147=IDA, GO:0000910=IEA, GO:0005737=IDA, GO:0005543=IEA, GO:0070830=IMP, GO:0005911=IDA, GO:0043089=IDA, GO:0071277=IDA, GO:0051260=IDA, GO:0004871=IMP, GO:0005089=IDA, GO:0043123=IMP, GO:0051056=TAS, GO:0048011=TAS, GO:0043065=IDA, GO:0051988=IMP, GO:0006915=TAS, GO:0030496=IDA, GO:0032862=IDA, GO:0032863=IMP, GO:0097190=TAS, GO:0071479=IDA, GO:0000902=IEA, GO:0032321=IMP, GO:0045666=ISS, GO:0042307=ISS, GO:0017048=IEA, GO:0097149=IDA, GO:0005923=IDA, GO:0005096=IMP} activation of Rac GTPase activity, activation of Rho GTPase activity, activation of protein kinase activity, apoptotic process, apoptotic signaling pathway, cell morphogenesis, cellular response to calcium ion, cellular response to hydrogen peroxide, cellular response to ionizing radiation, cytokinesis, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, positive regulation of Cdc42 GTPase activity, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of Rho GTPase activity, positive regulation of apoptotic process, positive regulation of neuron differentiation, positive regulation of protein import into nucleus, protein homooligomerization, protein transport, regulation of Rho protein signal transduction, regulation of attachment of spindle microtubules to kinetochore, regulation of protein kinase activity, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction, tight junction assembly cell-cell junction, centralspindlin complex, cleavage furrow, cytoplasm, cytosol, midbody, mitotic spindle, nucleus, tight junction GTPase activator activity, Rho GTPase binding, Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, phospholipid binding, protein binding, protein homodimerization activity, signal transducer activity Human UniProtKB:P16333 EDA HGNC UniProtKB {GO:0005515=PMID:11039935, GO:0042346=GO_REF:0000019, GO:0010467=GO_REF:0000019, GO:0005581=GO_REF:0000037, GO:0005886=PMID:9736768, GO:0090263=GO_REF:0000019, GO:0030154=GO_REF:0000037, GO:0006955=GO_REF:0000002, GO:0051092=PMID:11039935, GO:0042475=GO_REF:0000019, GO:0060662=GO_REF:0000019, GO:0043123=GO_REF:0000019, GO:0005856=PMID:10484778, GO:0005164=GO_REF:0000002, GO:0005102=PMID:11039935, GO:0045177=GO_REF:0000019, GO:0060789=GO_REF:0000019, GO:0007398=PMID:8696334, GO:0007165=PMID:8696334, GO:0007160=GO_REF:0000019, GO:0016020=PMID:8696334, GO:0061153=GO_REF:0000019, GO:0005887=GO_REF:0000019, GO:0043473=GO_REF:0000019, GO:0005789=GO_REF:0000019, GO:0043588=GO_REF:0000019, GO:0016021=PMID:8696334} Q92838 Ectodysplasin-A protein 20040813 {GO:0005515=IPI, GO:0042346=IEA, GO:0010467=IEA, GO:0005581=IEA, GO:0005886=TAS, GO:0090263=IEA, GO:0030154=IEA, GO:0006955=IEA, GO:0051092=IDA, GO:0042475=IEA, GO:0060662=IEA, GO:0043123=IEA, GO:0005856=TAS, GO:0005164=IEA, GO:0005102=IDA, GO:0045177=IEA, GO:0060789=IEA, GO:0007398=TAS, GO:0007165=TAS, GO:0007160=IEA, GO:0016020=TAS, GO:0061153=IEA, GO:0005887=IEA, GO:0043473=IEA, GO:0005789=IEA, GO:0043588=IEA, GO:0016021=TAS} cell differentiation, cell-matrix adhesion, ectoderm development, gene expression, hair follicle placode formation, immune response, odontogenesis of dentin-containing tooth, pigmentation, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB import into nucleus, positive regulation of NF-kappaB transcription factor activity, positive regulation of canonical Wnt receptor signaling pathway, salivary gland cavitation, signal transduction, skin development, trachea gland development apical part of cell, collagen, cytoskeleton, endoplasmic reticulum membrane, integral to membrane, integral to plasma membrane, membrane, plasma membrane protein binding, receptor binding, tumor necrosis factor receptor binding Human EDA2R GOC UniProtKB {GO:0005515=PMID:11039935, GO:0051092=PMID:11039935, GO:0005031=PMID:11039935, GO:0008544=PMID:11039935, GO:0005887=GO_REF:0000002, GO:0046330=PMID:12270937, GO:0004872=PMID:11039935, GO:0009790=PMID:12270937, GO:0016021=PMID:12270937, GO:0033209=PMID:11039935, GO:0030154=GO_REF:0000037} Q9HAV5 Tumor necrosis factor receptor superfamily member 27 protein 20130413 {GO:0005515=IPI, GO:0051092=IDA, GO:0005031=NAS, GO:0008544=NAS, GO:0005887=IEA, GO:0046330=IDA, GO:0004872=IDA, GO:0009790=NAS, GO:0016021=IC, GO:0033209=NAS, GO:0030154=IEA} cell differentiation, embryo development, epidermis development, positive regulation of JNK cascade, positive regulation of NF-kappaB transcription factor activity, tumor necrosis factor-mediated signaling pathway integral to membrane, integral to plasma membrane protein binding, receptor activity, tumor necrosis factor-activated receptor activity Human EDAR HGNC UniProtKB {GO:0005515=PMID:11039935, GO:0042346=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0045177=GO_REF:0000019, GO:0030154=GO_REF:0000037, GO:0007165=GO_REF:0000002, GO:0008544=PMID:12270937, GO:0043473=GO_REF:0000019, GO:0042475=GO_REF:0000019, GO:0004872=PMID:11039935, GO:0060662=GO_REF:0000019, GO:0016021=PMID:10431241, GO:0001942=GO_REF:0000019, GO:0004888=PMID:10431241} Q9UNE0 Tumor necrosis factor receptor superfamily member EDAR protein 20040813 {GO:0005515=IPI, GO:0042346=IEA, GO:0005886=IEA, GO:0006915=IEA, GO:0045177=IEA, GO:0030154=IEA, GO:0007165=IEA, GO:0008544=TAS, GO:0043473=IEA, GO:0042475=IEA, GO:0004872=IDA, GO:0060662=IEA, GO:0016021=NAS, GO:0001942=IEA, GO:0004888=NAS} apoptotic process, cell differentiation, epidermis development, hair follicle development, odontogenesis of dentin-containing tooth, pigmentation, positive regulation of NF-kappaB import into nucleus, salivary gland cavitation, signal transduction apical part of cell, integral to membrane, plasma membrane protein binding, receptor activity, transmembrane signaling receptor activity Human UniProtKB:Q92838 EDARADD UniProtKB UniProtKB {GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0061153=GO_REF:0000019, GO:0042475=GO_REF:0000019, GO:0001942=GO_REF:0000019, GO:0030154=GO_REF:0000037} Q8WWZ3 Ectodysplasin-A receptor-associated adapter protein protein 20130413 {GO:0007165=IEA, GO:0005737=IEA, GO:0061153=IEA, GO:0042475=IEA, GO:0001942=IEA, GO:0030154=IEA} cell differentiation, hair follicle development, odontogenesis of dentin-containing tooth, signal transduction, trachea gland development cytoplasm Human UniProtKB-SubCell:SL-0086 EDC3 IntAct UniProtKB {GO:0005515=PMID:16364915, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0000932=GO_REF:0000039, GO:0003723=GO_REF:0000037, GO:0043928=Reactome:REACT_20518, GO:0042802=PMID:18678652, GO:0005829=Reactome:REACT_20560, GO:0000288=Reactome:REACT_20639} Q96F86 Enhancer of mRNA-decapping protein 3 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0000932=IEA, GO:0003723=IEA, GO:0043928=TAS, GO:0042802=IPI, GO:0005829=TAS, GO:0000288=TAS} RNA metabolic process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay cytoplasmic mRNA processing body, cytosol RNA binding, identical protein binding, protein binding Human UniProtKB:Q96F86 EDC4 HPA UniProtKB {GO:0005515=PMID:21903422, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0005730=GO_REF:0000052, GO:0043928=Reactome:REACT_20518, GO:0005634=GO_REF:0000052, GO:0005829=Reactome:REACT_20560, GO:0043231=GO_REF:0000052, GO:0008150=GO_REF:0000015, GO:0005737=PMID:9067524, GO:0000932=PMID:20826699, GO:0000288=Reactome:REACT_20639} Q6P2E9 Enhancer of mRNA-decapping protein 4 protein 20110516 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0005730=IDA, GO:0043928=TAS, GO:0005634=IDA, GO:0005829=TAS, GO:0043231=IDA, GO:0008150=ND, GO:0005737=TAS, GO:0000932=IDA, GO:0000288=TAS} RNA metabolic process, biological_process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay cytoplasm, cytoplasmic mRNA processing body, cytosol, intracellular membrane-bounded organelle, nucleolus, nucleus protein binding Human EDEM1 Reactome UniProtKB {GO:0005515=PMID:19524542, GO:0004571=PMID:12610306, GO:0005509=GO_REF:0000002, GO:0030176=GO_REF:0000024, GO:0030433=GO_REF:0000024, GO:0030968=Reactome:REACT_18356, GO:0051787=PMID:19524542, GO:0016020=GO_REF:0000002, GO:0006457=Reactome:REACT_23878, GO:0005789=Reactome:REACT_116092, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0018279=Reactome:REACT_22426, GO:0043687=Reactome:REACT_22161} Q92611 ER degradation-enhancing alpha-mannosidase-like protein 1 protein 20130301 {GO:0005515=IPI, GO:0004571=IDA, GO:0005509=IEA, GO:0030176=ISS, GO:0030433=ISS, GO:0030968=TAS, GO:0051787=IDA, GO:0016020=IEA, GO:0006457=TAS, GO:0005789=TAS, GO:0006987=TAS, GO:0044267=TAS, GO:0018279=TAS, GO:0043687=TAS} ER-associated protein catabolic process, activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, post-translational protein modification, protein N-linked glycosylation via asparagine, protein folding endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane, membrane calcium ion binding, mannosyl-oligosaccharide 1,2-alpha-mannosidase activity, misfolded protein binding, protein binding Human EDEM2 Reactome UniProtKB {GO:0006986=GO_REF:0000037, GO:0016020=GO_REF:0000002, GO:0006457=Reactome:REACT_23878, GO:0005509=GO_REF:0000002, GO:0004571=PMID:15537790, GO:0005789=Reactome:REACT_25207, GO:0005788=GO_REF:0000039, GO:0005576=GO_REF:0000039, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q9BV94 ER degradation-enhancing alpha-mannosidase-like protein 2 protein 20130301 {GO:0006986=IEA, GO:0016020=IEA, GO:0006457=TAS, GO:0005509=IEA, GO:0004571=IDA, GO:0005789=TAS, GO:0005788=IEA, GO:0005576=IEA, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS} cellular protein metabolic process, post-translational protein modification, protein N-linked glycosylation via asparagine, protein folding, response to unfolded protein endoplasmic reticulum lumen, endoplasmic reticulum membrane, extracellular region, membrane calcium ion binding, mannosyl-oligosaccharide 1,2-alpha-mannosidase activity Human EDEM3 Reactome UniProtKB {GO:0006986=GO_REF:0000037, GO:0004571=GO_REF:0000003, GO:0005509=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0006457=Reactome:REACT_23878, GO:0005789=Reactome:REACT_25207, GO:0005788=GO_REF:0000039, GO:0006516=GO_REF:0000019, GO:0043161=GO_REF:0000019, GO:0004569=GO_REF:0000019, GO:0044267=Reactome:REACT_17015, GO:0018279=Reactome:REACT_22426, GO:0043687=Reactome:REACT_22161} Q9BZQ6 ER degradation-enhancing alpha-mannosidase-like protein 3 protein 20130301 {GO:0006986=IEA, GO:0004571=IEA, GO:0005509=IEA, GO:0016020=IEA, GO:0006457=TAS, GO:0005789=TAS, GO:0005788=IEA, GO:0006516=IEA, GO:0043161=IEA, GO:0004569=IEA, GO:0044267=TAS, GO:0018279=TAS, GO:0043687=TAS} cellular protein metabolic process, glycoprotein catabolic process, post-translational protein modification, proteasomal ubiquitin-dependent protein catabolic process, protein N-linked glycosylation via asparagine, protein folding, response to unfolded protein endoplasmic reticulum lumen, endoplasmic reticulum membrane, membrane calcium ion binding, glycoprotein endo-alpha-1,2-mannosidase activity, mannosyl-oligosaccharide 1,2-alpha-mannosidase activity Human EDF1 HPA UniProtKB {GO:0005515=PMID:12040021, GO:0005516=GO_REF:0000037, GO:0006355=PMID:12040021, GO:0005669=PMID:12040021, GO:0003700=PMID:12040021, GO:0003713=PMID:12040021, GO:0008168=PMID:12040021, GO:0005730=GO_REF:0000052, GO:0007275=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037, GO:0019216=PMID:12040021, GO:0005622=PMID:9813014, GO:0043565=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0043388=PMID:10567391, GO:0045446=PMID:12040021, GO:0045893=PMID:8164657, GO:0004402=PMID:12040021} O60869 Endothelial differentiation-related factor 1 protein 20101115 {GO:0005515=IPI, GO:0005516=IEA, GO:0006355=TAS, GO:0005669=IDA, GO:0003700=IMP, GO:0003713=IMP, GO:0008168=IDA, GO:0005730=IDA, GO:0007275=IEA, GO:0005634=IDA, GO:0006351=IEA, GO:0019216=TAS, GO:0005622=TAS, GO:0043565=IEA, GO:0005737=IDA, GO:0043388=IDA, GO:0045446=TAS, GO:0045893=TAS, GO:0004402=IDA} endothelial cell differentiation, multicellular organismal development, positive regulation of DNA binding, positive regulation of transcription, DNA-dependent, regulation of lipid metabolic process, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, intracellular, nucleolus, nucleus, transcription factor TFIID complex calmodulin binding, histone acetyltransferase activity, methyltransferase activity, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity Human EDIL3 PINC UniProtKB {GO:0005178=PMID:9420328, GO:0010811=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0007275=GO_REF:0000037, GO:0007155=GO_REF:0000037} O43854 EGF-like repeat and discoidin I-like domain-containing protein 3 protein 20030904 {GO:0005178=TAS, GO:0010811=IEA, GO:0005509=IEA, GO:0007275=IEA, GO:0007155=IEA} cell adhesion, multicellular organismal development, positive regulation of cell-substrate adhesion calcium ion binding, integrin binding Human EDN1 BHF-UCL UniProtKB {GO:0019722=PMID:10770212, GO:0051216=GO_REF:0000019, GO:0005615=PMID:10770212, GO:0006885=GO_REF:0000019, GO:0007243=GO_REF:0000019, GO:0019229=GO_REF:0000002, GO:0007507=GO_REF:0000019, GO:0046888=GO_REF:0000019, GO:0070101=PMID:17178876, GO:0015758=GO_REF:0000019, GO:0014032=GO_REF:0000019, GO:0001516=PMID:9492062, GO:0051482=GO_REF:0000019, GO:0046887=PMID:10770212, GO:0071356=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0003100=PMID:2649896, GO:0031583=GO_REF:0000019, GO:0030335=PMID:9696419, GO:0043179=GO_REF:0000019, GO:0030593=PMID:9696419, GO:0060137=GO_REF:0000019, GO:0045840=PMID:10770212, GO:0000122=PMID:19767294, GO:0060585=PMID:9492062, GO:0005125=PMID:19767294, GO:0014065=PMID:17078114, GO:0001701=GO_REF:0000019, GO:0032269=PMID:19767294, GO:0010595=PMID:8999856, GO:0045793=PMID:12847114, GO:0045321=PMID:16820593, GO:0007186=PMID:17078114, GO:0005179=PMID:2649896, GO:0035815=GO_REF:0000019, GO:0071347=GO_REF:0000019, GO:0090023=GO_REF:0000019, GO:0016049=GO_REF:0000019, GO:0010460=PMID:2649896, GO:0030072=PMID:10770212, GO:0035810=GO_REF:0000019, GO:0051930=GO_REF:0000019, GO:0008284=PMID:1917960, GO:0051899=GO_REF:0000019, GO:0042482=GO_REF:0000019, GO:0030818=GO_REF:0000019, GO:0007267=PMID:12379507, GO:0031707=PMID:10770212, GO:0010259=GO_REF:0000019, GO:0010870=PMID:17178876, GO:0009953=GO_REF:0000019, GO:0031708=PMID:10770212, GO:0007204=PMID:1917960, GO:0007205=GO_REF:0000019, GO:0045429=PMID:8999856, GO:0042313=PMID:16820593, GO:0042045=GO_REF:0000019, GO:0005737=PMID:12379507, GO:0045987=GO_REF:0000019, GO:0043406=PMID:10770212, GO:0030185=PMID:16820593, GO:0042310=PMID:2649896, GO:0042474=GO_REF:0000019, GO:0043507=PMID:12847114, GO:0043200=GO_REF:0000019, GO:0010613=PMID:12847114, GO:0042554=GO_REF:0000019, GO:0014824=PMID:8982507, GO:0007589=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0014826=PMID:9422810, GO:0001569=GO_REF:0000019, GO:0001821=GO_REF:0000019, GO:0007585=GO_REF:0000019, GO:0048016=PMID:1917960, GO:0005576=Reactome:REACT_22436, GO:0033574=GO_REF:0000019, GO:0048661=PMID:10393673, GO:0019233=GO_REF:0000019, GO:0034392=GO_REF:0000019, GO:0060298=PMID:12847114, GO:0030195=PMID:16820593, GO:0051771=PMID:16820593, GO:0007166=PMID:1713452, GO:0035094=GO_REF:0000019} P05305 Endothelin-1 protein 20110318 {GO:0019722=IDA, GO:0051216=IEA, GO:0005615=IDA, GO:0006885=IEA, GO:0007243=IEA, GO:0019229=IEA, GO:0007507=IEA, GO:0046888=IEA, GO:0070101=IC, GO:0015758=IEA, GO:0014032=IEA, GO:0001516=IDA, GO:0051482=IEA, GO:0046887=IDA, GO:0071356=IEA, GO:0032496=IEA, GO:0003100=IDA, GO:0031583=IEA, GO:0030335=IDA, GO:0043179=IEA, GO:0030593=IDA, GO:0060137=IEA, GO:0045840=IDA, GO:0000122=IDA, GO:0060585=IMP, GO:0005125=IDA, GO:0014065=IDA, GO:0001701=IEA, GO:0032269=IDA, GO:0010595=TAS, GO:0045793=IDA, GO:0045321=TAS, GO:0007186=IDA, GO:0005179=IDA, GO:0035815=IEA, GO:0071347=IEA, GO:0090023=IEA, GO:0016049=IEA, GO:0010460=IDA, GO:0030072=IDA, GO:0035810=IEA, GO:0051930=IEA, GO:0008284=IDA, GO:0051899=IEA, GO:0042482=IEA, GO:0030818=IEA, GO:0007267=IDA, GO:0031707=IDA, GO:0010259=IEA, GO:0010870=IDA, GO:0009953=IEA, GO:0031708=IDA, GO:0007204=IDA, GO:0007205=IEA, GO:0045429=TAS, GO:0042313=IDA, GO:0042045=IEA, GO:0005737=IDA, GO:0045987=IEA, GO:0043406=IDA, GO:0030185=IDA, GO:0042310=IDA, GO:0042474=IEA, GO:0043507=IDA, GO:0043200=IEA, GO:0010613=IDA, GO:0042554=IEA, GO:0014824=IDA, GO:0007589=IEA, GO:0001666=IEA, GO:0014826=IDA, GO:0001569=IEA, GO:0001821=IEA, GO:0007585=IEA, GO:0048016=IDA, GO:0005576=TAS, GO:0033574=IEA, GO:0048661=IDA, GO:0019233=IEA, GO:0034392=IEA, GO:0060298=IMP, GO:0030195=TAS, GO:0051771=IDA, GO:0007166=IDA, GO:0035094=IEA} G-protein coupled receptor signaling pathway, artery smooth muscle contraction, body fluid secretion, calcium-mediated signaling, cartilage development, cell growth, cell surface receptor signaling pathway, cell-cell signaling, cellular response to interleukin-1, cellular response to tumor necrosis factor, dorsal/ventral pattern formation, elevation of cytosolic calcium ion concentration, elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway, epithelial fluid transport, glucose transport, heart development, histamine secretion, in utero embryonic development, inositol phosphate-mediated signaling, intracellular protein kinase cascade, leukocyte activation, maternal process involved in parturition, membrane depolarization, middle ear morphogenesis, multicellular organismal aging, negative regulation of blood coagulation, negative regulation of cAMP biosynthetic process, negative regulation of cellular protein metabolic process, negative regulation of hormone secretion, negative regulation of nitric-oxide synthase biosynthetic process, negative regulation of smooth muscle cell apoptotic process, negative regulation of transcription from RNA polymerase II promoter, neural crest cell development, neutrophil chemotaxis, nitric oxide transport, patterning of blood vessels, peptide hormone secretion, phosphatidylinositol 3-kinase cascade, phospholipase D-activating G-protein coupled receptor signaling pathway, positive regulation of JUN kinase activity, positive regulation of MAP kinase activity, positive regulation of cardiac muscle hypertrophy, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of cell size, positive regulation of chemokine-mediated signaling pathway, positive regulation of endothelial cell migration, positive regulation of heart rate, positive regulation of hormone secretion, positive regulation of mitosis, positive regulation of neutrophil chemotaxis, positive regulation of nitric oxide biosynthetic process, positive regulation of odontogenesis, positive regulation of prostaglandin-endoperoxide synthase activity, positive regulation of receptor biosynthetic process, positive regulation of renal sodium excretion, positive regulation of sarcomere organization, positive regulation of smooth muscle cell proliferation, positive regulation of smooth muscle contraction, positive regulation of urine volume, prostaglandin biosynthetic process, protein kinase C deactivation, protein kinase C-activating G-protein coupled receptor signaling pathway, regulation of pH, regulation of sensory perception of pain, regulation of systemic arterial blood pressure by endothelin, regulation of vasoconstriction, respiratory gaseous exchange, response to amino acid stimulus, response to hypoxia, response to lipopolysaccharide, response to nicotine, response to testosterone stimulus, rhythmic excitation, sensory perception of pain, superoxide anion generation, vasoconstriction, vein smooth muscle contraction cytoplasm, extracellular region, extracellular space cytokine activity, endothelin A receptor binding, endothelin B receptor binding, hormone activity Human EDN2 BHF-UCL UniProtKB {GO:0014824=PMID:8982507, GO:0008284=PMID:1917960, GO:0014826=PMID:8982507, GO:0019722=PMID:1917960, GO:0030593=PMID:9696419, GO:0019221=PMID:12207323, GO:0048016=PMID:1917960, GO:0005576=Reactome:REACT_22436, GO:0060585=PMID:9492062, GO:0005615=PMID:15691296, GO:0007204=PMID:1917960, GO:0002690=PMID:9696419, GO:0019229=GO_REF:0000002, GO:0005179=PMID:2649896, GO:0042116=PMID:12207323, GO:0001516=PMID:9492062, GO:0003058=PMID:1652300, GO:0045987=GO_REF:0000019, GO:0042310=PMID:2649896, GO:0003099=PMID:1652300, GO:0010460=PMID:2649896, GO:0048246=PMID:12207323, GO:0003100=PMID:2649896, GO:0007166=PMID:1713452} P20800 Endothelin-2 protein 20080903 {GO:0014824=IDA, GO:0008284=IDA, GO:0014826=IDA, GO:0019722=IDA, GO:0030593=IDA, GO:0019221=IDA, GO:0048016=IDA, GO:0005576=TAS, GO:0060585=IMP, GO:0005615=IDA, GO:0007204=IDA, GO:0002690=IDA, GO:0019229=IEA, GO:0005179=IDA, GO:0042116=IDA, GO:0001516=IDA, GO:0003058=TAS, GO:0045987=IEA, GO:0042310=IDA, GO:0003099=TAS, GO:0010460=IDA, GO:0048246=IDA, GO:0003100=IDA, GO:0007166=IC} artery smooth muscle contraction, calcium-mediated signaling, cell surface receptor signaling pathway, cytokine-mediated signaling pathway, elevation of cytosolic calcium ion concentration, hormonal regulation of the force of heart contraction, inositol phosphate-mediated signaling, macrophage activation, macrophage chemotaxis, neutrophil chemotaxis, positive regulation of cell proliferation, positive regulation of heart rate, positive regulation of leukocyte chemotaxis, positive regulation of prostaglandin-endoperoxide synthase activity, positive regulation of smooth muscle contraction, positive regulation of the force of heart contraction by chemical signal, prostaglandin biosynthetic process, regulation of systemic arterial blood pressure by endothelin, regulation of vasoconstriction, vasoconstriction, vein smooth muscle contraction extracellular region, extracellular space hormone activity Human EDN3 InterPro UniProtKB {GO:0008284=GO_REF:0000019, GO:0008015=PMID:8298278, GO:0001755=GO_REF:0000019, GO:0007267=PMID:8298278, GO:0005615=PMID:15691296, GO:0019229=GO_REF:0000002, GO:0043406=PMID:10770212, GO:0030182=GO_REF:0000019, GO:0042310=PMID:2649896, GO:0046887=PMID:10770212, GO:0003100=PMID:2649896, GO:0014824=PMID:8982507, GO:0014826=PMID:8982507, GO:0030593=PMID:9696419, GO:0048016=PMID:1917960, GO:0005102=PMID:8298278, GO:0005576=GO_REF:0000002, GO:0007275=PMID:8630502, GO:0030318=GO_REF:0000019, GO:0045840=PMID:10770212, GO:0002690=PMID:9696419, GO:0007165=PMID:8298278, GO:0048070=GO_REF:0000019, GO:0005179=PMID:2649896, GO:0010460=PMID:2649896, GO:0030072=PMID:10770212, GO:0007166=PMID:1713452} Q4FAT2 Endothelin-3 protein 20130413 {GO:0008284=IEA, GO:0008015=TAS, GO:0001755=IEA, GO:0007267=TAS, GO:0005615=IDA, GO:0019229=IEA, GO:0043406=IDA, GO:0030182=IEA, GO:0042310=IDA, GO:0046887=IDA, GO:0003100=IDA, GO:0014824=IDA, GO:0014826=IDA, GO:0030593=IDA, GO:0048016=IDA, GO:0005102=TAS, GO:0005576=IEA, GO:0007275=TAS, GO:0030318=IEA, GO:0045840=IDA, GO:0002690=IDA, GO:0007165=TAS, GO:0048070=IEA, GO:0005179=IDA, GO:0010460=IDA, GO:0030072=IDA, GO:0007166=IDA} artery smooth muscle contraction, blood circulation, cell surface receptor signaling pathway, cell-cell signaling, inositol phosphate-mediated signaling, melanocyte differentiation, multicellular organismal development, neural crest cell migration, neuron differentiation, neutrophil chemotaxis, peptide hormone secretion, positive regulation of MAP kinase activity, positive regulation of cell proliferation, positive regulation of heart rate, positive regulation of hormone secretion, positive regulation of leukocyte chemotaxis, positive regulation of mitosis, regulation of developmental pigmentation, regulation of systemic arterial blood pressure by endothelin, regulation of vasoconstriction, signal transduction, vasoconstriction, vein smooth muscle contraction extracellular region, extracellular space hormone activity, receptor binding Human InterPro:IPR001928|InterPro:IPR019764 EDNRA BHF-UCL UniProtKB {GO:0007507=GO_REF:0000019, GO:0006939=PMID:9284755, GO:0014032=GO_REF:0000019, GO:0015758=GO_REF:0000024, GO:0051482=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0070374=GO_REF:0000019, GO:0050678=GO_REF:0000019, GO:0031965=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0060137=GO_REF:0000019, GO:0043278=GO_REF:0000019, GO:0043084=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0048484=GO_REF:0000002, GO:0007186=PMID:8611157, GO:0005887=PMID:1326535, GO:0090023=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0042482=GO_REF:0000019, GO:0090184=GO_REF:0000019, GO:0005886=Reactome:REACT_22436, GO:0008283=PMID:9284755, GO:0030818=GO_REF:0000019, GO:0007266=GO_REF:0000019, GO:0007202=PMID:8702836, GO:0048144=GO_REF:0000019, GO:0007204=PMID:1849646, GO:0007205=GO_REF:0000019, GO:0007190=PMID:8702836, GO:0042310=PMID:8982507, GO:0051281=GO_REF:0000019, GO:0014824=PMID:8982507, GO:0001666=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0001569=GO_REF:0000019, GO:0001821=GO_REF:0000019, GO:0007585=GO_REF:0000024, GO:0030315=GO_REF:0000019, GO:0019233=GO_REF:0000019, GO:0007165=PMID:1326535, GO:0048659=GO_REF:0000019, GO:0016020=GO_REF:0000029, GO:0003094=GO_REF:0000019, GO:0004435=PMID:8702836, GO:0004962=PMID:8611157, GO:0050729=GO_REF:0000019, GO:0008217=GO_REF:0000002, GO:0001934=GO_REF:0000019, GO:0060322=GO_REF:0000019, GO:0071260=GO_REF:0000019} P25101 Endothelin-1 receptor protein 20080903 {GO:0007507=IEA, GO:0006939=NAS, GO:0014032=IEA, GO:0015758=ISS, GO:0051482=IEA, GO:0032496=IEA, GO:0070374=IEA, GO:0050678=IEA, GO:0031965=IEA, GO:0007568=IEA, GO:0060137=IEA, GO:0043278=IEA, GO:0043084=IEA, GO:0001701=IEA, GO:0048484=IEA, GO:0007186=NAS, GO:0005887=TAS, GO:0090023=IEA, GO:0008284=IEA, GO:0042482=IEA, GO:0090184=IEA, GO:0005886=TAS, GO:0008283=NAS, GO:0030818=IEA, GO:0007266=IEA, GO:0007202=TAS, GO:0048144=IEA, GO:0007204=TAS, GO:0007205=IEA, GO:0007190=TAS, GO:0042310=IMP, GO:0051281=IEA, GO:0014824=IMP, GO:0001666=IEA, GO:0043066=IEA, GO:0001569=IEA, GO:0001821=IEA, GO:0007585=ISS, GO:0030315=IEA, GO:0019233=IEA, GO:0007165=TAS, GO:0048659=IEA, GO:0016020=NAS, GO:0003094=IEA, GO:0004435=TAS, GO:0004962=NAS, GO:0050729=IEA, GO:0008217=IEA, GO:0001934=IEA, GO:0060322=IEA, GO:0071260=IEA} G-protein coupled receptor signaling pathway, Rho protein signal transduction, activation of adenylate cyclase activity, activation of phospholipase C activity, aging, artery smooth muscle contraction, cell proliferation, cellular response to mechanical stimulus, elevation of cytosolic calcium ion concentration, elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway, enteric nervous system development, fibroblast proliferation, glomerular filtration, glucose transport, head development, heart development, histamine secretion, in utero embryonic development, maternal process involved in parturition, negative regulation of apoptotic process, negative regulation of cAMP biosynthetic process, neural crest cell development, patterning of blood vessels, penile erection, positive regulation of ERK1 and ERK2 cascade, positive regulation of cell proliferation, positive regulation of inflammatory response, positive regulation of kidney development, positive regulation of neutrophil chemotaxis, positive regulation of odontogenesis, positive regulation of protein phosphorylation, positive regulation of release of sequestered calcium ion into cytosol, protein kinase C-activating G-protein coupled receptor signaling pathway, regulation of blood pressure, regulation of epithelial cell proliferation, respiratory gaseous exchange, response to hypoxia, response to lipopolysaccharide, response to morphine, sensory perception of pain, signal transduction, smooth muscle cell proliferation, smooth muscle contraction, vasoconstriction T-tubule, integral to plasma membrane, membrane, nuclear membrane, plasma membrane endothelin receptor activity, phosphatidylinositol phospholipase C activity Human EDNRB GOC UniProtKB {GO:0014070=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0005886=Reactome:REACT_22436, GO:0060406=GO_REF:0000019, GO:0001755=GO_REF:0000019, GO:0007200=GO_REF:0000019, GO:0019934=GO_REF:0000019, GO:0007194=PMID:9556633, GO:0007204=GO_REF:0000019, GO:0031702=GO_REF:0000019, GO:0006885=GO_REF:0000019, GO:0042045=GO_REF:0000019, GO:0042311=GO_REF:0000019, GO:0042310=PMID:8982507, GO:0050678=GO_REF:0000019, GO:0014826=PMID:8982507, GO:0031965=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0086100=PMID:19767294, GO:0007568=GO_REF:0000019, GO:0014043=GO_REF:0000024, GO:0030318=GO_REF:0000019, GO:0000122=PMID:19767294, GO:0032269=PMID:19767294, GO:0019233=GO_REF:0000019, GO:0048484=GO_REF:0000024, GO:0007399=PMID:8001158, GO:0071222=GO_REF:0000019, GO:0005887=PMID:8810293, GO:0004962=PMID:1713452, GO:0007422=GO_REF:0000019, GO:0035815=GO_REF:0000019, GO:0008217=GO_REF:0000019, GO:0001934=GO_REF:0000019, GO:0007497=GO_REF:0000019, GO:0045121=GO_REF:0000019, GO:0048265=GO_REF:0000019, GO:0048246=PMID:12207323, GO:0017046=PMID:1713452, GO:0035810=GO_REF:0000019, GO:0007166=PMID:8810293, GO:0035645=GO_REF:0000024, GO:0051930=GO_REF:0000019} P24530 Endothelin B receptor protein 20130413 {GO:0014070=IEA, GO:0008284=IEA, GO:0005886=TAS, GO:0060406=IEA, GO:0001755=IEA, GO:0007200=IEA, GO:0019934=IEA, GO:0007194=TAS, GO:0007204=IEA, GO:0031702=IEA, GO:0006885=IEA, GO:0042045=IEA, GO:0042311=IEA, GO:0042310=IMP, GO:0050678=IEA, GO:0014826=IMP, GO:0031965=IEA, GO:0043066=IEA, GO:0086100=IMP, GO:0007568=IEA, GO:0014043=ISS, GO:0030318=IEA, GO:0000122=IMP, GO:0032269=IMP, GO:0019233=IEA, GO:0048484=ISS, GO:0007399=TAS, GO:0071222=IEA, GO:0005887=TAS, GO:0004962=IDA, GO:0007422=IEA, GO:0035815=IEA, GO:0008217=IEA, GO:0001934=IEA, GO:0007497=IEA, GO:0045121=IEA, GO:0048265=IEA, GO:0048246=IMP, GO:0017046=IPI, GO:0035810=IEA, GO:0007166=TAS, GO:0035645=ISS, GO:0051930=IEA} aging, cGMP-mediated signaling, cell surface receptor signaling pathway, cellular response to lipopolysaccharide, elevation of cytosolic calcium ion concentration, endothelin receptor signaling pathway, enteric nervous system development, enteric smooth muscle cell differentiation, epithelial fluid transport, macrophage chemotaxis, melanocyte differentiation, negative regulation of adenylate cyclase activity, negative regulation of apoptotic process, negative regulation of cellular protein metabolic process, negative regulation of neuron maturation, negative regulation of transcription from RNA polymerase II promoter, nervous system development, neural crest cell migration, peripheral nervous system development, phospholipase C-activating G-protein coupled receptor signaling pathway, positive regulation of cell proliferation, positive regulation of penile erection, positive regulation of protein phosphorylation, positive regulation of renal sodium excretion, positive regulation of urine volume, posterior midgut development, regulation of blood pressure, regulation of epithelial cell proliferation, regulation of pH, regulation of sensory perception of pain, response to organic cyclic compound, response to pain, sensory perception of pain, vasoconstriction, vasodilation, vein smooth muscle contraction integral to plasma membrane, membrane raft, nuclear membrane, plasma membrane endothelin receptor activity, peptide hormone binding, type 1 angiotensin receptor binding Human EEA1 HPA UniProtKB {GO:0005515=PMID:11870209, GO:0005516=PMID:11741531, GO:0005969=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0045022=PMID:7768953, GO:0006906=PMID:9697774, GO:0042803=PMID:11741531, GO:0006897=PMID:21081650, GO:0005829=PMID:7768953, GO:0005545=PMID:11256955, GO:0005737=GO_REF:0000052, GO:0030742=PMID:10491193, GO:0016020=PMID:7768953, GO:0031901=GO_REF:0000039, GO:0016189=PMID:11741531, GO:0008270=PMID:11741531, GO:0055037=GO_REF:0000019, GO:0005769=PMID:19535332, GO:0019897=PMID:7768953} Q15075 Early endosome antigen 1 protein 20111111 {GO:0005515=IPI, GO:0005516=NAS, GO:0005969=IEA, GO:0005886=IDA, GO:0045022=NAS, GO:0006906=IMP, GO:0042803=IDA, GO:0006897=IMP, GO:0005829=IDA, GO:0005545=IDA, GO:0005737=IDA, GO:0030742=IDA, GO:0016020=TAS, GO:0031901=IEA, GO:0016189=TAS, GO:0008270=TAS, GO:0055037=IEA, GO:0005769=IDA, GO:0019897=IDA} early endosome to late endosome transport, endocytosis, synaptic vesicle to endosome fusion, vesicle fusion cytoplasm, cytosol, early endosome, early endosome membrane, extrinsic to plasma membrane, membrane, plasma membrane, recycling endosome, serine-pyruvate aminotransferase complex 1-phosphatidylinositol binding, GTP-dependent protein binding, calmodulin binding, protein binding, protein homodimerization activity, zinc ion binding Human EED IntAct UniProtKB {GO:0005515=PMID:23238014, GO:0035098=PMID:15385962, GO:0016571=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0006349=GO_REF:0000019, GO:0005634=PMID:9584199, GO:0045120=GO_REF:0000019, GO:0045892=PMID:9584199, GO:0001739=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0042054=PMID:15385962} O75530 Polycomb protein EED protein 20130415 {GO:0005515=IPI, GO:0035098=IDA, GO:0016571=IEA, GO:0003682=IEA, GO:0006349=IEA, GO:0005634=NAS, GO:0045120=IEA, GO:0045892=NAS, GO:0001739=IEA, GO:0006351=IEA, GO:0042054=IDA} histone methylation, negative regulation of transcription, DNA-dependent, regulation of gene expression by genetic imprinting, transcription, DNA-dependent ESC/E(Z) complex, nucleus, pronucleus, sex chromatin chromatin binding, histone methyltransferase activity, protein binding Human UniProtKB:Q16531 EEF1A1 ENSEMBL UniProtKB {GO:0005515=PMID:18000879, GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000037, GO:0005853=PMID:2564392, GO:0019901=PMID:17595531, GO:0003924=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0005525=GO_REF:0000002, GO:0003746=PMID:17595531, GO:0006412=Reactome:REACT_1014, GO:0006351=GO_REF:0000037, GO:0006414=Reactome:REACT_1477, GO:0005829=Reactome:REACT_67, GO:0005737=GO_REF:0000019, GO:0044267=Reactome:REACT_17015} Q5JR01 Elongation factor 1-alpha 1 protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0006355=IEA, GO:0005853=TAS, GO:0019901=IPI, GO:0003924=IEA, GO:0005634=IEA, GO:0005525=IEA, GO:0003746=TAS, GO:0006412=TAS, GO:0006351=IEA, GO:0006414=TAS, GO:0005829=TAS, GO:0005737=IEA, GO:0044267=TAS} cellular protein metabolic process, gene expression, regulation of transcription, DNA-dependent, transcription, DNA-dependent, translation, translational elongation cytoplasm, cytosol, eukaryotic translation elongation factor 1 complex, nucleus GTP binding, GTPase activity, protein binding, protein kinase binding, translation elongation factor activity Human Ensembl:ENSMUSP00000042457 EEF1A2 PINC UniProtKB {GO:0043066=GO_REF:0000019, GO:0005853=GO_REF:0000019, GO:0010035=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0003924=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003746=GO_REF:0000019, GO:0005525=GO_REF:0000037, GO:0008135=PMID:8812466} Q05639 Elongation factor 1-alpha 2 protein 20040811 {GO:0043066=IEA, GO:0005853=IEA, GO:0010035=IEA, GO:0043025=IEA, GO:0003924=IEA, GO:0005634=IEA, GO:0003746=IEA, GO:0005525=IEA, GO:0008135=NAS} negative regulation of apoptotic process, response to inorganic substance eukaryotic translation elongation factor 1 complex, neuronal cell body, nucleus GTP binding, GTPase activity, translation elongation factor activity, translation factor activity, nucleic acid binding Human EEF1B2 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0010467=Reactome:REACT_71, GO:0005853=PMID:1886777, GO:0003746=PMID:1886777, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0005829=Reactome:REACT_1395, GO:0006414=Reactome:REACT_1477} P24534 Elongation factor 1-beta protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0005853=NAS, GO:0003746=NAS, GO:0044267=TAS, GO:0006412=TAS, GO:0005829=TAS, GO:0006414=TAS} cellular protein metabolic process, gene expression, translation, translational elongation cytosol, eukaryotic translation elongation factor 1 complex protein binding, translation elongation factor activity Human UniProtKB:P26641 EEF1D GOC UniProtKB {GO:0005515=PMID:20195357, GO:0010467=Reactome:REACT_71, GO:0005853=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003746=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0006412=Reactome:REACT_1014, GO:0006351=GO_REF:0000037, GO:0005829=Reactome:REACT_1395, GO:0006414=Reactome:REACT_1477, GO:0007165=PMID:12761501, GO:0004871=PMID:12761501, GO:0043123=PMID:12761501, GO:0044267=Reactome:REACT_17015, GO:0008135=PMID:8334168} P29692 Elongation factor 1-delta protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0005853=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0003746=IEA, GO:0003677=IEA, GO:0006412=TAS, GO:0006351=IEA, GO:0005829=TAS, GO:0006414=TAS, GO:0007165=IMP, GO:0004871=IMP, GO:0043123=IMP, GO:0044267=TAS, GO:0008135=TAS} cellular protein metabolic process, gene expression, positive regulation of I-kappaB kinase/NF-kappaB cascade, regulation of transcription, DNA-dependent, signal transduction, transcription, DNA-dependent, translation, translational elongation cytosol, eukaryotic translation elongation factor 1 complex, nucleus DNA binding, protein binding, signal transducer activity, translation elongation factor activity, translation factor activity, nucleic acid binding Human EEF1E1 HPA UniProtKB {GO:0005515=PMID:22190034, GO:0010467=Reactome:REACT_71, GO:0005737=GO_REF:0000052, GO:0043065=GO_REF:0000024, GO:0008285=GO_REF:0000024, GO:0043517=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006418=Reactome:REACT_15482, GO:0005829=Reactome:REACT_15516} O43324 Eukaryotic translation elongation factor 1 epsilon-1 protein 20101115 {GO:0005515=IPI, GO:0010467=TAS, GO:0005737=IDA, GO:0043065=ISS, GO:0008285=ISS, GO:0043517=ISS, GO:0005730=IDA, GO:0005634=IDA, GO:0006418=TAS, GO:0005829=TAS} gene expression, negative regulation of cell proliferation, positive regulation of DNA damage response, signal transduction by p53 class mediator, positive regulation of apoptotic process, tRNA aminoacylation for protein translation cytoplasm, cytosol, nucleolus, nucleus protein binding Human EEF1G IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0005622=GO_REF:0000029, GO:0010467=Reactome:REACT_71, GO:0005853=GO_REF:0000002, GO:0009615=PMID:16548883, GO:0003746=GO_REF:0000029, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0005829=Reactome:REACT_1395, GO:0006414=Reactome:REACT_1477} P26641 Elongation factor 1-gamma protein 20130415 {GO:0005515=IPI, GO:0005622=NAS, GO:0010467=TAS, GO:0005853=IEA, GO:0009615=IEP, GO:0003746=NAS, GO:0044267=TAS, GO:0006412=TAS, GO:0005829=TAS, GO:0006414=TAS} cellular protein metabolic process, gene expression, response to virus, translation, translational elongation cytosol, eukaryotic translation elongation factor 1 complex, intracellular protein binding, translation elongation factor activity Human UniProtKB:P29692 EEF2 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0030529=PMID:18809582, GO:0003924=GO_REF:0000019, GO:0005525=GO_REF:0000037, GO:0003746=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0005844=GO_REF:0000019, GO:0006414=Reactome:REACT_1477, GO:0005829=Reactome:REACT_2173} P13639 Elongation factor 2 protein 20130213 {GO:0010467=TAS, GO:0030529=IDA, GO:0003924=IEA, GO:0005525=IEA, GO:0003746=IEA, GO:0044267=TAS, GO:0006412=TAS, GO:0005844=IEA, GO:0006414=TAS, GO:0005829=TAS} cellular protein metabolic process, gene expression, translation, translational elongation cytosol, polysome, ribonucleoprotein complex GTP binding, GTPase activity, translation elongation factor activity Human EEF2K Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005516=PMID:9144159, GO:0005509=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0006414=PMID:9144159, GO:0005829=Reactome:REACT_6883, GO:0031952=GO_REF:0000019, GO:0005737=PMID:9144159, GO:0046777=PMID:9144159, GO:0004672=PMID:9144159, GO:0004674=GO_REF:0000002, GO:0004686=PMID:9144159, GO:0008135=PMID:9144159} O00418 Eukaryotic elongation factor 2 kinase protein 20130301 {GO:0008286=TAS, GO:0005516=IDA, GO:0005509=IEA, GO:0005524=IEA, GO:0006414=TAS, GO:0005829=TAS, GO:0031952=IEA, GO:0005737=TAS, GO:0046777=IDA, GO:0004672=TAS, GO:0004674=IEA, GO:0004686=IDA, GO:0008135=TAS} insulin receptor signaling pathway, protein autophosphorylation, regulation of protein autophosphorylation, translational elongation cytoplasm, cytosol ATP binding, calcium ion binding, calmodulin binding, elongation factor-2 kinase activity, protein kinase activity, protein serine/threonine kinase activity, translation factor activity, nucleic acid binding Human EEFSEC GOC UniProtKB {GO:0006184=GO_REF:0000029, GO:0005739=GO_REF:0000019, GO:0005737=GO_REF:0000029, GO:0000049=GO_REF:0000019, GO:0001514=GO_REF:0000019, GO:0003924=GO_REF:0000029, GO:0005634=GO_REF:0000029, GO:0003746=GO_REF:0000029, GO:0005525=GO_REF:0000019, GO:0006414=GO_REF:0000029} P57772 Selenocysteine-specific elongation factor protein 20130413 {GO:0006184=NAS, GO:0005739=IEA, GO:0005737=NAS, GO:0000049=IEA, GO:0001514=IEA, GO:0003924=NAS, GO:0005634=NAS, GO:0003746=NAS, GO:0005525=IEA, GO:0006414=NAS} GTP catabolic process, selenocysteine incorporation, translational elongation cytoplasm, mitochondrion, nucleus GTP binding, GTPase activity, tRNA binding, translation elongation factor activity Human EEPD1 InterPro UniProtKB {GO:0006281=GO_REF:0000002, GO:0003677=GO_REF:0000002} Q7L9B9 Endonuclease/exonuclease/phosphatase family domain-containing protein 1 protein 20130413 {GO:0006281=IEA, GO:0003677=IEA} DNA repair DNA binding Human InterPro:IPR003583 EFCAB1 InterPro UniProtKB {GO:0005509=GO_REF:0000002} Q9HAE3 EF-hand calcium-binding domain-containing protein 1 protein 20130413 {GO:0005509=IEA} calcium ion binding Human InterPro:IPR001125|InterPro:IPR002048|InterPro:IPR011992 EFCAB11 InterPro UniProtKB {GO:0005509=GO_REF:0000002} Q9BUY7 EF-hand calcium-binding domain-containing protein 11 protein 20130413 {GO:0005509=IEA} calcium ion binding Human InterPro:IPR002048|InterPro:IPR011992 EFCAB4A UniProtKB UniProtKB {GO:0005737=GO_REF:0000019, GO:0002115=PMID:20418871, GO:0005509=GO_REF:0000002, GO:2001256=GO_REF:0000019, GO:0034613=GO_REF:0000019} Q8N4Y2 EF-hand calcium-binding domain-containing protein 4A protein 20100430 {GO:0005737=IEA, GO:0002115=IMP, GO:0005509=IEA, GO:2001256=IEA, GO:0034613=IEA} cellular protein localization, regulation of store-operated calcium entry, store-operated calcium entry cytoplasm calcium ion binding Human EFCAB4B HPA UniProtKB {GO:0005515=PMID:20418871, GO:0032237=PMID:20418871, GO:0005737=GO_REF:0000052, GO:0002115=PMID:20418871, GO:0005794=GO_REF:0000052, GO:0051928=PMID:20418871, GO:0005509=PMID:20418871, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9BSW2 EF-hand calcium-binding domain-containing protein 4B protein 20110516 {GO:0005515=IPI, GO:0032237=IMP, GO:0005737=IDA, GO:0002115=IMP, GO:0005794=IDA, GO:0051928=IMP, GO:0005509=IDA, GO:0005730=IDA, GO:0005634=IDA} activation of store-operated calcium channel activity, positive regulation of calcium ion transport, store-operated calcium entry Golgi apparatus, cytoplasm, nucleolus, nucleus calcium ion binding, protein binding Human EFCAB5 InterPro UniProtKB {GO:0005509=GO_REF:0000002} K7EJC3 EF-hand calcium-binding domain-containing protein 5 protein 20130413 {GO:0005509=IEA} calcium ion binding Human InterPro:IPR002048|InterPro:IPR011992 EFCAB6 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005509=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q5THR3 EF-hand calcium-binding domain-containing protein 6 protein 20130413 {GO:0006355=IEA, GO:0005509=IEA, GO:0005634=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus calcium ion binding Human UniProtKB-SubCell:SL-0191 EFEMP1 InterPro UniProtKB {GO:0005515=PMID:16713569, GO:0006355=PMID:20005202, GO:0005154=PMID:19804359, GO:0005509=GO_REF:0000002, GO:0005578=GO_REF:0000039, GO:0018108=PMID:19804359, GO:0005576=Reactome:REACT_150335, GO:0005615=PMID:20005202, GO:0005006=PMID:19804359, GO:0007173=PMID:19804359, GO:0030198=Reactome:REACT_118779, GO:0032331=PMID:20005202, GO:0008083=GO_REF:0000037, GO:0007601=PMID:10369267} Q580Q6 EGF-containing fibulin-like extracellular matrix protein 1 protein 20130413 {GO:0005515=IPI, GO:0006355=IDA, GO:0005154=IDA, GO:0005509=IEA, GO:0005578=IEA, GO:0018108=IDA, GO:0005576=TAS, GO:0005615=IDA, GO:0005006=IDA, GO:0007173=IDA, GO:0030198=TAS, GO:0032331=IDA, GO:0008083=IEA, GO:0007601=TAS} epidermal growth factor receptor signaling pathway, extracellular matrix organization, negative regulation of chondrocyte differentiation, peptidyl-tyrosine phosphorylation, regulation of transcription, DNA-dependent, visual perception extracellular region, extracellular space, proteinaceous extracellular matrix calcium ion binding, epidermal growth factor receptor binding, epidermal growth factor-activated receptor activity, growth factor activity, protein binding Human InterPro:IPR001881|InterPro:IPR018097 EFEMP2 IntAct UniProtKB {GO:0005515=PMID:23088713, GO:0016020=GO_REF:0000002, GO:0030198=Reactome:REACT_118779, GO:0007596=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0005576=Reactome:REACT_150335, GO:0005604=PMID:10601734, GO:0005201=PMID:10601734, GO:0004888=GO_REF:0000002} O95967 EGF-containing fibulin-like extracellular matrix protein 2 protein 20130415 {GO:0005515=IPI, GO:0016020=IEA, GO:0030198=TAS, GO:0007596=IEA, GO:0005509=IEA, GO:0005576=TAS, GO:0005604=TAS, GO:0005201=TAS, GO:0004888=IEA} blood coagulation, extracellular matrix organization basement membrane, extracellular region, membrane calcium ion binding, extracellular matrix structural constituent, protein binding, transmembrane signaling receptor activity Human UniProtKB:P09022 EFHC1 UniProtKB UniProtKB {GO:0005929=GO_REF:0000019, GO:0005930=GO_REF:0000024, GO:0005509=GO_REF:0000002, GO:0043025=GO_REF:0000024, GO:0008022=GO_REF:0000024} Q5JVL4 EF-hand domain-containing protein 1 protein 20060201 {GO:0005929=IEA, GO:0005930=ISS, GO:0005509=IEA, GO:0043025=ISS, GO:0008022=ISS} axoneme, cilium, neuronal cell body calcium ion binding, protein C-terminus binding Human UniProtKB:Q9D9T8 EFHC2 InterPro UniProtKB {GO:0005509=GO_REF:0000002} Q5JST6 EF-hand domain-containing family member C2 protein 20130413 {GO:0005509=IEA} calcium ion binding Human InterPro:IPR002048|InterPro:IPR011992 EFHD1 ENSEMBL UniProtKB {GO:0005509=GO_REF:0000002, GO:0005743=GO_REF:0000019, GO:0031175=GO_REF:0000019} Q9BUP0 EF-hand domain-containing protein D1 protein 20130413 {GO:0005509=IEA, GO:0005743=IEA, GO:0031175=IEA} neuron projection development mitochondrial inner membrane calcium ion binding Human Ensembl:ENSMUSP00000027472 EFHD2 UniProtKB UniProtKB {GO:0005509=GO_REF:0000019, GO:0045121=GO_REF:0000039} Q96C19 EF-hand domain-containing protein D2 protein 20130413 {GO:0005509=IEA, GO:0045121=IEA} membrane raft calcium ion binding Human UniProtKB-SubCell:SL-0370 EFNA1 BHF-UCL UniProtKB {GO:0005515=PMID:19573808, GO:0033628=PMID:10655584, GO:0003180=GO_REF:0000024, GO:0050730=GO_REF:0000024, GO:0003183=GO_REF:0000024, GO:0007267=PMID:8660976, GO:0050731=PMID:10655584, GO:0010719=GO_REF:0000024, GO:0014028=GO_REF:0000019, GO:0000187=GO_REF:0000019, GO:0030182=GO_REF:0000019, GO:0034446=PMID:10655584, GO:0046658=GO_REF:0000019, GO:0061002=GO_REF:0000024, GO:0003199=GO_REF:0000024, GO:0048013=PMID:10655584, GO:0005102=PMID:8660976, GO:0045765=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0000122=GO_REF:0000024, GO:0001525=GO_REF:0000037, GO:0043535=GO_REF:0000019, GO:0046875=PMID:15777695, GO:0016477=PMID:10655584, GO:0005887=PMID:8660976, GO:0050770=GO_REF:0000019} P20827 Ephrin-A1 protein 20110228 {GO:0005515=IPI, GO:0033628=IDA, GO:0003180=ISS, GO:0050730=ISS, GO:0003183=ISS, GO:0007267=TAS, GO:0050731=IDA, GO:0010719=ISS, GO:0014028=IEA, GO:0000187=IEA, GO:0030182=IEA, GO:0034446=IDA, GO:0046658=IEA, GO:0061002=ISS, GO:0003199=ISS, GO:0048013=IDA, GO:0005102=TAS, GO:0045765=IEA, GO:0005576=IEA, GO:0000122=ISS, GO:0001525=IEA, GO:0043535=IEA, GO:0046875=IPI, GO:0016477=IDA, GO:0005887=TAS, GO:0050770=IEA} activation of MAPK activity, angiogenesis, aortic valve morphogenesis, cell migration, cell-cell signaling, endocardial cushion to mesenchymal transition involved in heart valve formation, ephrin receptor signaling pathway, mitral valve morphogenesis, negative regulation of dendritic spine morphogenesis, negative regulation of epithelial to mesenchymal transition, negative regulation of transcription from RNA polymerase II promoter, neuron differentiation, notochord formation, positive regulation of peptidyl-tyrosine phosphorylation, regulation of angiogenesis, regulation of axonogenesis, regulation of blood vessel endothelial cell migration, regulation of cell adhesion mediated by integrin, regulation of peptidyl-tyrosine phosphorylation, substrate adhesion-dependent cell spreading anchored to plasma membrane, extracellular region, integral to plasma membrane ephrin receptor binding, protein binding, receptor binding Human UniProtKB:P52793 EFNA2 PINC UniProtKB {GO:0046849=GO_REF:0000024, GO:0048013=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0046875=GO_REF:0000019, GO:0007267=PMID:9826538, GO:0030316=GO_REF:0000024, GO:0031225=GO_REF:0000037} O43921 Ephrin-A2 protein 20030904 {GO:0046849=ISS, GO:0048013=ISS, GO:0005886=IEA, GO:0046875=IEA, GO:0007267=TAS, GO:0030316=ISS, GO:0031225=IEA} bone remodeling, cell-cell signaling, ephrin receptor signaling pathway, osteoclast differentiation anchored to membrane, plasma membrane ephrin receptor binding Human EFNA3 PINC UniProtKB {GO:0005005=PMID:8660976, GO:0048013=GO_REF:0000024, GO:0046875=PMID:15777695, GO:0016020=GO_REF:0000038, GO:0005887=PMID:8660976, GO:0007267=PMID:8660976, GO:0031225=GO_REF:0000037} P52797 Ephrin-A3 protein 20030904 {GO:0005005=TAS, GO:0048013=ISS, GO:0046875=IPI, GO:0016020=IEA, GO:0005887=TAS, GO:0007267=TAS, GO:0031225=IEA} cell-cell signaling, ephrin receptor signaling pathway anchored to membrane, integral to plasma membrane, membrane ephrin receptor binding, transmembrane-ephrin receptor activity Human EFNA4 PINC UniProtKB {GO:0005515=PMID:15777695, GO:0005005=PMID:8660976, GO:0046875=PMID:15777695, GO:0016020=GO_REF:0000038, GO:0005887=PMID:8660976, GO:0007267=PMID:8660976, GO:0005576=GO_REF:0000039, GO:0031225=GO_REF:0000037} P52798 Ephrin-A4 protein 20030904 {GO:0005515=IPI, GO:0005005=TAS, GO:0046875=IPI, GO:0016020=IEA, GO:0005887=TAS, GO:0007267=TAS, GO:0005576=IEA, GO:0031225=IEA} cell-cell signaling anchored to membrane, extracellular region, integral to plasma membrane, membrane ephrin receptor binding, protein binding, transmembrane-ephrin receptor activity Human EFNA5 PINC UniProtKB {GO:0031290=GO_REF:0000019, GO:0022407=PMID:11870224, GO:0048013=PMID:11870224, GO:0005886=GO_REF:0000024, GO:0050731=GO_REF:0000024, GO:0006915=PMID:11870224, GO:0031362=PMID:11870224, GO:0051893=PMID:11870224, GO:0007399=PMID:9245480, GO:0070507=PMID:11870224, GO:0045499=GO_REF:0000019, GO:0032314=GO_REF:0000024, GO:0016020=GO_REF:0000038, GO:0046875=PMID:11870224, GO:0005901=GO_REF:0000039, GO:0032956=PMID:11870224, GO:0032319=PMID:11870224, GO:0061178=GO_REF:0000024} P52803 Ephrin-A5 protein 20031119 {GO:0031290=IEA, GO:0022407=IDA, GO:0048013=IDA, GO:0005886=ISS, GO:0050731=ISS, GO:0006915=IDA, GO:0031362=IDA, GO:0051893=IDA, GO:0007399=TAS, GO:0070507=IDA, GO:0045499=IEA, GO:0032314=ISS, GO:0016020=IEA, GO:0046875=IPI, GO:0005901=IEA, GO:0032956=IDA, GO:0032319=IDA, GO:0061178=ISS} apoptotic process, ephrin receptor signaling pathway, nervous system development, positive regulation of peptidyl-tyrosine phosphorylation, regulation of Rac GTPase activity, regulation of Rho GTPase activity, regulation of actin cytoskeleton organization, regulation of cell-cell adhesion, regulation of focal adhesion assembly, regulation of insulin secretion involved in cellular response to glucose stimulus, regulation of microtubule cytoskeleton organization, retinal ganglion cell axon guidance anchored to external side of plasma membrane, caveola, membrane, plasma membrane chemorepellent activity, ephrin receptor binding Human EFNB1 PINC UniProtKB {GO:0005515=PMID:9883737, GO:0001755=GO_REF:0000019, GO:0007267=PMID:8798744, GO:0045202=GO_REF:0000024, GO:0005634=GO_REF:0000019, GO:0009880=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0046875=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0005887=PMID:8660976, GO:0042102=GO_REF:0000019, GO:0045121=GO_REF:0000019, GO:0007155=PMID:8798744} P98172 Ephrin-B1 protein 20030904 {GO:0005515=IPI, GO:0001755=IEA, GO:0007267=TAS, GO:0045202=ISS, GO:0005634=IEA, GO:0009880=IEA, GO:0005737=IEA, GO:0046875=IEA, GO:0007411=IEA, GO:0005887=TAS, GO:0042102=IEA, GO:0045121=IEA, GO:0007155=TAS} axon guidance, cell adhesion, cell-cell signaling, embryonic pattern specification, neural crest cell migration, positive regulation of T cell proliferation cytoplasm, integral to plasma membrane, membrane raft, nucleus, synapse ephrin receptor binding, protein binding Human EFNB2 BHF-UCL UniProtKB {GO:0048013=PMID:12734395, GO:0005886=PMID:8660976, GO:0007267=PMID:8559144, GO:0002042=PMID:12734395, GO:0009653=PMID:9630219, GO:0030154=GO_REF:0000037, GO:2000727=PMID:17336907, GO:0007399=GO_REF:0000037, GO:0046875=PMID:16867992, GO:0050920=PMID:12734395, GO:0005887=PMID:8660976, GO:0019048=GO_REF:0000037, GO:0009887=GO_REF:0000019, GO:0007155=PMID:12734395, GO:0001945=GO_REF:0000019} P52799 Ephrin-B2 protein 20120925 {GO:0048013=IDA, GO:0005886=TAS, GO:0007267=TAS, GO:0002042=IDA, GO:0009653=TAS, GO:0030154=IEA, GO:2000727=ISS, GO:0007399=IEA, GO:0046875=IPI, GO:0050920=IDA, GO:0005887=TAS, GO:0019048=IEA, GO:0009887=IEA, GO:0007155=IDA, GO:0001945=IEA} anatomical structure morphogenesis, cell adhesion, cell differentiation, cell migration involved in sprouting angiogenesis, cell-cell signaling, ephrin receptor signaling pathway, lymph vessel development, nervous system development, organ morphogenesis, positive regulation of cardiac muscle cell differentiation, regulation of chemotaxis, virus-host interaction integral to plasma membrane, plasma membrane ephrin receptor binding Human UniProtKB:P52800 EFNB3 MGI UniProtKB {GO:0005005=PMID:9126477, GO:0048013=PMID:8808709, GO:0046875=PMID:8808709, GO:0005887=PMID:9126477, GO:0016198=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0007267=PMID:9126477, GO:0007628=GO_REF:0000019, GO:0007399=PMID:9126477} Q15768 Ephrin-B3 protein 20070125 {GO:0005005=TAS, GO:0048013=IDA, GO:0046875=IDA, GO:0005887=TAS, GO:0016198=IEA, GO:0019048=IEA, GO:0007267=TAS, GO:0007628=IEA, GO:0007399=TAS} adult walking behavior, axon choice point recognition, cell-cell signaling, ephrin receptor signaling pathway, nervous system development, virus-host interaction integral to plasma membrane ephrin receptor binding, transmembrane-ephrin receptor activity Human EFR3A UniProtKB UniProtKB {GO:0005622=GO_REF:0000019, GO:0005886=GO_REF:0000039} Q14156 Protein EFR3 homolog A protein 20130413 {GO:0005622=IEA, GO:0005886=IEA} intracellular, plasma membrane Human UniProtKB-SubCell:SL-0039 EFR3B null null {} null null null null {} null null null EFS PINC UniProtKB {GO:0035556=PMID:9349509, GO:0005737=PMID:9349509, GO:0017124=GO_REF:0000019, GO:0019904=PMID:11984006, GO:0007155=GO_REF:0000037} O43281 Embryonal Fyn-associated substrate protein 20030904 {GO:0035556=TAS, GO:0005737=TAS, GO:0017124=IEA, GO:0019904=IPI, GO:0007155=IEA} cell adhesion, intracellular signal transduction cytoplasm SH3 domain binding, protein domain specific binding Human EFTUD1 UniProtKB UniProtKB {GO:0006184=PMID:21536732, GO:0042256=PMID:21536732, GO:0003924=PMID:21536732, GO:0043022=PMID:21536732, GO:0003746=GO_REF:0000037, GO:0005525=GO_REF:0000037} Q7Z2Z2 Elongation factor Tu GTP-binding domain-containing protein 1 protein 20110516 {GO:0006184=IDA, GO:0042256=IMP, GO:0003924=IDA, GO:0043022=IMP, GO:0003746=IEA, GO:0005525=IEA} GTP catabolic process, mature ribosome assembly GTP binding, GTPase activity, ribosome binding, translation elongation factor activity Human EFTUD2 GOC UniProtKB {GO:0005515=PMID:17314511, GO:0006397=PMID:9233818, GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0015030=PMID:15257298, GO:0005730=GO_REF:0000052, GO:0003924=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0005525=GO_REF:0000037, GO:0071013=PMID:11991638, GO:0006184=PMID:9233818, GO:0005737=GO_REF:0000052, GO:0016607=PMID:15257298, GO:0000398=Reactome:REACT_1753, GO:0005681=PMID:9233818, GO:0005654=Reactome:REACT_2241} Q15029 116 kDa U5 small nuclear ribonucleoprotein component protein 20130413 {GO:0005515=IPI, GO:0006397=TAS, GO:0008380=TAS, GO:0010467=TAS, GO:0015030=IDA, GO:0005730=IDA, GO:0003924=IEA, GO:0005634=IDA, GO:0005525=IEA, GO:0071013=IDA, GO:0006184=TAS, GO:0005737=IDA, GO:0016607=IDA, GO:0000398=TAS, GO:0005681=TAS, GO:0005654=TAS} GTP catabolic process, RNA splicing, gene expression, mRNA processing, mRNA splicing, via spliceosome Cajal body, catalytic step 2 spliceosome, cytoplasm, nuclear speck, nucleolus, nucleoplasm, nucleus, spliceosomal complex GTP binding, GTPase activity, protein binding Human EGF GOC UniProtKB {GO:0005515=PMID:12620237, GO:0005154=PMID:15611079, GO:0008284=PMID:20388803, GO:0005886=GO_REF:0000019, GO:0051048=PMID:10559227, GO:0007262=GO_REF:0000024, GO:0021940=GO_REF:0000019, GO:0035413=PMID:20302655, GO:0005615=GO_REF:0000019, GO:2000008=PMID:19996314, GO:0007171=PMID:9712850, GO:0000186=GO_REF:0000019, GO:0030297=PMID:9712850, GO:0007173=Reactome:REACT_9417, GO:0043406=PMID:15611079, GO:0031093=Reactome:REACT_21351, GO:0070371=PMID:16314496, GO:0048011=Reactome:REACT_11061, GO:0090279=PMID:19996314, GO:0048015=Reactome:REACT_12464, GO:0045741=PMID:15611079, GO:0005509=GO_REF:0000002, GO:0042059=Reactome:REACT_12484, GO:0030168=Reactome:REACT_798, GO:0018108=GO_REF:0000019, GO:0045840=PMID:15611079, GO:0005576=Reactome:REACT_147854, GO:0001525=PMID:15611079, GO:0006260=PMID:9482941, GO:0007165=Reactome:REACT_12478, GO:2000060=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0043388=GO_REF:0000024, GO:0002576=Reactome:REACT_318, GO:0090370=GO_REF:0000019, GO:0048754=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0008083=PMID:7736574, GO:0060749=GO_REF:0000019, GO:0042327=PMID:15611079} P01133 Pro-epidermal growth factor protein 20130413 {GO:0005515=IPI, GO:0005154=TAS, GO:0008284=IDA, GO:0005886=IEA, GO:0051048=IDA, GO:0007262=ISS, GO:0021940=IEA, GO:0035413=IDA, GO:0005615=IEA, GO:2000008=IDA, GO:0007171=TAS, GO:0000186=IEA, GO:0030297=TAS, GO:0007173=TAS, GO:0043406=IDA, GO:0031093=TAS, GO:0070371=IDA, GO:0048011=TAS, GO:0090279=IDA, GO:0048015=TAS, GO:0045741=IDA, GO:0005509=IEA, GO:0042059=TAS, GO:0030168=TAS, GO:0018108=IEA, GO:0045840=IDA, GO:0005576=TAS, GO:0001525=IDA, GO:0006260=TAS, GO:0007165=TAS, GO:2000060=IEA, GO:0008543=TAS, GO:0007596=TAS, GO:0045087=TAS, GO:0043388=ISS, GO:0002576=TAS, GO:0090370=IEA, GO:0048754=IEA, GO:0016021=IEA, GO:0008083=IDA, GO:0060749=IEA, GO:0042327=IDA} DNA replication, ERK1 and ERK2 cascade, STAT protein import into nucleus, activation of MAPKK activity, activation of transmembrane receptor protein tyrosine kinase activity, angiogenesis, blood coagulation, branching morphogenesis of an epithelial tube, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, mammary gland alveolus development, negative regulation of cholesterol efflux, negative regulation of epidermal growth factor receptor signaling pathway, negative regulation of secretion, neurotrophin TRK receptor signaling pathway, peptidyl-tyrosine phosphorylation, phosphatidylinositol-mediated signaling, platelet activation, platelet degranulation, positive regulation of DNA binding, positive regulation of MAP kinase activity, positive regulation of catenin import into nucleus, positive regulation of cell proliferation, positive regulation of cerebellar granule cell precursor proliferation, positive regulation of epidermal growth factor-activated receptor activity, positive regulation of mitosis, positive regulation of phosphorylation, positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process, regulation of calcium ion import, regulation of protein localization to cell surface, signal transduction extracellular region, extracellular space, integral to membrane, plasma membrane, platelet alpha granule lumen calcium ion binding, epidermal growth factor receptor binding, growth factor activity, protein binding, transmembrane receptor protein tyrosine kinase activator activity Human EGFL6 PINC UniProtKB {GO:0007049=PMID:10610727, GO:0005178=PMID:10610727, GO:0016020=GO_REF:0000002, GO:0030198=GO_REF:0000019, GO:0010811=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0007275=GO_REF:0000037, GO:0007155=GO_REF:0000037, GO:0005615=PMID:10610727, GO:0030154=GO_REF:0000037, GO:0005604=GO_REF:0000039} Q8IUX8 Epidermal growth factor-like protein 6 protein 20070906 {GO:0007049=TAS, GO:0005178=TAS, GO:0016020=IEA, GO:0030198=IEA, GO:0010811=IEA, GO:0005509=IEA, GO:0007275=IEA, GO:0007155=IEA, GO:0005615=TAS, GO:0030154=IEA, GO:0005604=IEA} cell adhesion, cell cycle, cell differentiation, extracellular matrix organization, multicellular organismal development, positive regulation of cell-substrate adhesion basement membrane, extracellular space, membrane calcium ion binding, integrin binding Human EGFL7 UniProtKB UniProtKB {GO:0030336=GO_REF:0000019, GO:0001568=GO_REF:0000024, GO:0005509=GO_REF:0000002, GO:0005576=GO_REF:0000024, GO:0001525=GO_REF:0000037, GO:0001570=GO_REF:0000024, GO:0005615=GO_REF:0000019} Q9UHF1 Epidermal growth factor-like protein 7 protein 20041109 {GO:0030336=IEA, GO:0001568=ISS, GO:0005509=IEA, GO:0005576=ISS, GO:0001525=IEA, GO:0001570=ISS, GO:0005615=IEA} angiogenesis, blood vessel development, negative regulation of cell migration, vasculogenesis extracellular region, extracellular space calcium ion binding Human UniProtKB:Q9QXT5 EGFL8 UniProtKB UniProtKB {GO:0008474=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000029, GO:0001701=GO_REF:0000024, GO:0006464=GO_REF:0000002} Q99944 Epidermal growth factor-like protein 8 protein 20041109 {GO:0008474=IEA, GO:0005509=IEA, GO:0005576=IEA, GO:0016021=NAS, GO:0001701=ISS, GO:0006464=IEA} cellular protein modification process, in utero embryonic development extracellular region, integral to membrane calcium ion binding, palmitoyl-(protein) hydrolase activity Human EGFLAM UniProtKB UniProtKB {GO:0019800=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0030198=GO_REF:0000019, GO:0010811=GO_REF:0000019, GO:0045202=GO_REF:0000039, GO:0005539=GO_REF:0000019, GO:0005614=GO_REF:0000019, GO:0005604=GO_REF:0000019} Q63HQ2 Pikachurin protein 20130413 {GO:0019800=IEA, GO:0030054=IEA, GO:0030198=IEA, GO:0010811=IEA, GO:0045202=IEA, GO:0005539=IEA, GO:0005614=IEA, GO:0005604=IEA} extracellular matrix organization, peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan, positive regulation of cell-substrate adhesion basement membrane, cell junction, interstitial matrix, synapse glycosaminoglycan binding Human UniProtKB-SubCell:SL-0258 EGFR UniProtKB UniProtKB {GO:0005515=PMID:10805725, GO:0050730=PMID:12435727, GO:0060571=GO_REF:0000019, GO:0005615=PMID:9103388, GO:0042802=PMID:22579287, GO:0005006=PMID:17115032, GO:0016337=PMID:12435727, GO:0021795=GO_REF:0000019, GO:0046777=PMID:18070883, GO:0003690=PMID:6325948, GO:0051015=PMID:14702346, GO:0007173=Reactome:REACT_9417, GO:0000165=PMID:15542601, GO:0007411=Reactome:REACT_18266, GO:0001942=GO_REF:0000019, GO:0004709=PMID:15542601, GO:0050679=PMID:10572067, GO:0031965=GO_REF:0000039, GO:0030335=PMID:12435727, GO:0046982=PMID:10572067, GO:0070435=GO_REF:0000024, GO:0030122=PMID:14702346, GO:0019903=PMID:15899872, GO:0045740=PMID:17115032, GO:0051205=PMID:12435727, GO:0042059=Reactome:REACT_12484, GO:0006950=PMID:12828935, GO:0001892=GO_REF:0000019, GO:0048546=GO_REF:0000019, GO:0070141=PMID:18483258, GO:0001503=PMID:12925580, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0005789=GO_REF:0000039, GO:0045121=PMID:12009895, GO:0019899=PMID:12009895, GO:0010008=GO_REF:0000039, GO:0004888=PMID:7736574, GO:0043006=PMID:12435727, GO:0051897=PMID:17655843, GO:0008284=PMID:7736574, GO:0048471=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0008283=PMID:17115032, GO:0050999=PMID:12828935, GO:0005634=PMID:17115032, GO:0030139=GO_REF:0000019, GO:0048146=GO_REF:0000019, GO:0007202=PMID:12435727, GO:0045739=PMID:17115032, GO:0035413=PMID:20302655, GO:0045429=PMID:12828935, GO:0016323=PMID:12646923, GO:0000186=PMID:15542601, GO:0005737=GO_REF:0000052, GO:0043406=PMID:10572067, GO:0030235=PMID:12828935, GO:0007435=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0043066=PMID:18070883, GO:0042177=PMID:17115032, GO:0048015=Reactome:REACT_12464, GO:0005524=GO_REF:0000038, GO:0000902=GO_REF:0000019, GO:0007165=Reactome:REACT_12478, GO:0031659=PMID:18483258, GO:0000139=GO_REF:0000039, GO:0016020=PMID:12435727, GO:0016021=GO_REF:0000002, GO:0004713=Reactome:REACT_12569, GO:0004714=GO_REF:0000002, GO:0007169=GO_REF:0000002, GO:0007166=PMID:7736574, GO:0004716=GO_REF:0000002, GO:0042327=PMID:15082764, GO:0005768=PMID:17182860} Q504U8 Epidermal growth factor receptor protein 20130413 {GO:0005515=IPI, GO:0050730=IMP, GO:0060571=IEA, GO:0005615=NAS, GO:0042802=IPI, GO:0005006=IDA, GO:0016337=IMP, GO:0021795=IEA, GO:0046777=IMP, GO:0003690=NAS, GO:0051015=IDA, GO:0007173=TAS, GO:0000165=NAS, GO:0007411=TAS, GO:0001942=IEA, GO:0004709=NAS, GO:0050679=IDA, GO:0031965=IEA, GO:0030335=IMP, GO:0046982=IDA, GO:0070435=ISS, GO:0030122=TAS, GO:0019903=IPI, GO:0045740=IDA, GO:0051205=TAS, GO:0042059=TAS, GO:0006950=NAS, GO:0001892=IEA, GO:0048546=IEA, GO:0070141=IDA, GO:0001503=NAS, GO:0008543=TAS, GO:0045087=TAS, GO:0005789=IEA, GO:0045121=IDA, GO:0019899=IPI, GO:0010008=IEA, GO:0004888=IDA, GO:0043006=TAS, GO:0051897=IMP, GO:0008284=IDA, GO:0048471=IEA, GO:0005886=IDA, GO:0008283=IDA, GO:0050999=IDA, GO:0005634=IDA, GO:0030139=IEA, GO:0048146=IEA, GO:0007202=TAS, GO:0045739=IDA, GO:0035413=IMP, GO:0045429=IDA, GO:0016323=IDA, GO:0000186=NAS, GO:0005737=IDA, GO:0043406=IDA, GO:0030235=IDA, GO:0007435=IEA, GO:0048011=TAS, GO:0043066=IMP, GO:0042177=IDA, GO:0048015=TAS, GO:0005524=IEA, GO:0000902=IEA, GO:0007165=TAS, GO:0031659=IDA, GO:0000139=IEA, GO:0016020=IDA, GO:0016021=IEA, GO:0004713=TAS, GO:0004714=IEA, GO:0007169=IEA, GO:0007166=IDA, GO:0004716=IEA, GO:0042327=IDA, GO:0005768=IDA} MAPK cascade, activation of MAPKK activity, activation of phospholipase A2 activity by calcium-mediated signaling, activation of phospholipase C activity, axon guidance, cell morphogenesis, cell proliferation, cell surface receptor signaling pathway, cell-cell adhesion, cerebral cortex cell migration, digestive tract morphogenesis, embryonic placenta development, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, hair follicle development, innate immune response, morphogenesis of an epithelial fold, negative regulation of apoptotic process, negative regulation of epidermal growth factor receptor signaling pathway, negative regulation of protein catabolic process, neurotrophin TRK receptor signaling pathway, ossification, phosphatidylinositol-mediated signaling, positive regulation of DNA repair, positive regulation of DNA replication, positive regulation of MAP kinase activity, positive regulation of catenin import into nucleus, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S, positive regulation of epithelial cell proliferation, positive regulation of fibroblast proliferation, positive regulation of nitric oxide biosynthetic process, positive regulation of phosphorylation, positive regulation of protein kinase B signaling cascade, protein autophosphorylation, protein insertion into membrane, regulation of nitric-oxide synthase activity, regulation of peptidyl-tyrosine phosphorylation, response to UV-A, response to stress, salivary gland morphogenesis, signal transduction, transmembrane receptor protein tyrosine kinase signaling pathway AP-2 adaptor complex, Golgi membrane, Shc-EGFR complex, basolateral plasma membrane, cytoplasm, endocytic vesicle, endoplasmic reticulum membrane, endosome, endosome membrane, extracellular space, integral to membrane, membrane, membrane raft, nuclear membrane, nucleus, perinuclear region of cytoplasm, plasma membrane ATP binding, MAP kinase kinase kinase activity, actin filament binding, double-stranded DNA binding, enzyme binding, epidermal growth factor-activated receptor activity, identical protein binding, nitric-oxide synthase regulator activity, protein binding, protein heterodimerization activity, protein phosphatase binding, protein tyrosine kinase activity, receptor signaling protein tyrosine kinase activity, transmembrane receptor protein tyrosine kinase activity, transmembrane signaling receptor activity Human UniProtKB-KW:KW-0067 EGLN1 IntAct UniProtKB {GO:0031545=PMID:11598268, GO:0005515=PMID:15721254, GO:0001666=PMID:16956324, GO:0031543=PMID:16956324, GO:0060711=GO_REF:0000019, GO:0031418=GO_REF:0000037, GO:0005506=GO_REF:0000002, GO:0060412=GO_REF:0000019, GO:0071731=PMID:21601578, GO:0071456=Reactome:REACT_121311, GO:0061418=Reactome:REACT_120815, GO:0045765=GO_REF:0000024, GO:0033554=Reactome:REACT_120956, GO:0005634=GO_REF:0000039, GO:0043433=PMID:16956324, GO:0005829=Reactome:REACT_121242, GO:0060347=GO_REF:0000019, GO:0005737=PMID:12615973, GO:0018401=PMID:11598268, GO:0008270=GO_REF:0000002, GO:0016702=GO_REF:0000037, GO:0032364=PMID:16956324, GO:0055008=GO_REF:0000019} Q9GZT9 Egl nine homolog 1 protein 20130415 {GO:0031545=IDA, GO:0005515=IPI, GO:0001666=IDA, GO:0031543=TAS, GO:0060711=IEA, GO:0031418=IEA, GO:0005506=IEA, GO:0060412=IEA, GO:0071731=IDA, GO:0071456=TAS, GO:0061418=TAS, GO:0045765=ISS, GO:0033554=TAS, GO:0005634=IEA, GO:0043433=IDA, GO:0005829=TAS, GO:0060347=IEA, GO:0005737=IDA, GO:0018401=IDA, GO:0008270=IEA, GO:0016702=IEA, GO:0032364=IDA, GO:0055008=IEA} cardiac muscle tissue morphogenesis, cellular response to hypoxia, cellular response to stress, heart trabecula formation, labyrinthine layer development, negative regulation of sequence-specific DNA binding transcription factor activity, oxygen homeostasis, peptidyl-proline hydroxylation to 4-hydroxy-L-proline, regulation of angiogenesis, regulation of transcription from RNA polymerase II promoter in response to hypoxia, response to hypoxia, response to nitric oxide, ventricular septum morphogenesis cytoplasm, cytosol, nucleus L-ascorbic acid binding, iron ion binding, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, peptidyl-proline 4-dioxygenase activity, peptidyl-proline dioxygenase activity, protein binding, zinc ion binding Human UniProtKB:Q13438 EGLN2 LIFEdb UniProtKB {GO:0005515=PMID:22286099, GO:0031545=PMID:11598268, GO:0001666=PMID:11595184, GO:0045732=PMID:11595184, GO:0031418=GO_REF:0000037, GO:0071456=Reactome:REACT_121311, GO:0061418=Reactome:REACT_120815, GO:0033554=Reactome:REACT_120956, GO:0005634=GO_REF:0000054, GO:0001558=PMID:11850811, GO:0008198=PMID:12039559, GO:0043523=PMID:19587290, GO:0018401=PMID:11598268, GO:0019826=PMID:11595184, GO:0016706=PMID:11595184, GO:0005654=Reactome:REACT_120973, GO:0045454=PMID:11595184, GO:0016702=GO_REF:0000037, GO:0030520=PMID:11850811} Q96KS0 Egl nine homolog 2 protein 20100607 {GO:0005515=IPI, GO:0031545=IDA, GO:0001666=IDA, GO:0045732=IDA, GO:0031418=IEA, GO:0071456=TAS, GO:0061418=TAS, GO:0033554=TAS, GO:0005634=IDA, GO:0001558=NAS, GO:0008198=NAS, GO:0043523=IMP, GO:0018401=IDA, GO:0019826=IDA, GO:0016706=IDA, GO:0005654=TAS, GO:0045454=IDA, GO:0016702=IEA, GO:0030520=NAS} cell redox homeostasis, cellular response to hypoxia, cellular response to stress, intracellular estrogen receptor signaling pathway, peptidyl-proline hydroxylation to 4-hydroxy-L-proline, positive regulation of protein catabolic process, regulation of cell growth, regulation of neuron apoptotic process, regulation of transcription from RNA polymerase II promoter in response to hypoxia, response to hypoxia nucleoplasm, nucleus L-ascorbic acid binding, ferrous iron binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, oxygen sensor activity, peptidyl-proline 4-dioxygenase activity, protein binding Human EGLN3 Reactome UniProtKB {GO:0031545=PMID:11598268, GO:0005515=PMID:22286099, GO:0001666=PMID:20978507, GO:0031418=GO_REF:0000037, GO:0005506=GO_REF:0000002, GO:0006919=PMID:20978507, GO:0071456=Reactome:REACT_121311, GO:0061418=Reactome:REACT_120815, GO:0006915=PMID:20978507, GO:0033554=Reactome:REACT_120956, GO:0005634=PMID:12615973, GO:0006974=GO_REF:0000037, GO:0005829=Reactome:REACT_121242, GO:0043523=GO_REF:0000024, GO:0005737=PMID:12615973, GO:0018126=PMID:19584355, GO:0042127=PMID:20978507, GO:0018401=PMID:11598268, GO:0016706=GO_REF:0000002, GO:0005654=Reactome:REACT_120973, GO:0016702=GO_REF:0000037} Q9H6Z9 Egl nine homolog 3 protein 20130301 {GO:0031545=IDA, GO:0005515=IPI, GO:0001666=IEP, GO:0031418=IEA, GO:0005506=IEA, GO:0006919=IEP, GO:0071456=TAS, GO:0061418=TAS, GO:0006915=IEP, GO:0033554=TAS, GO:0005634=IDA, GO:0006974=IEA, GO:0005829=TAS, GO:0043523=ISS, GO:0005737=IDA, GO:0018126=IDA, GO:0042127=IEP, GO:0018401=IDA, GO:0016706=IEA, GO:0005654=TAS, GO:0016702=IEA} activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, cellular response to hypoxia, cellular response to stress, peptidyl-proline hydroxylation to 4-hydroxy-L-proline, protein hydroxylation, regulation of cell proliferation, regulation of neuron apoptotic process, regulation of transcription from RNA polymerase II promoter in response to hypoxia, response to DNA damage stimulus, response to hypoxia cytoplasm, cytosol, nucleoplasm, nucleus L-ascorbic acid binding, iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, peptidyl-proline 4-dioxygenase activity, protein binding Human EGR1 BHF-UCL UniProtKB {GO:0005515=PMID:19057511, GO:0003700=PMID:12560508, GO:0006366=PMID:19057511, GO:0048709=GO_REF:0000019, GO:0019221=Reactome:REACT_25229, GO:0060291=GO_REF:0000019, GO:0042220=GO_REF:0000019, GO:0043525=GO_REF:0000019, GO:0003690=GO_REF:0000019, GO:0072303=GO_REF:0000024, GO:0060337=Reactome:REACT_25162, GO:0051602=GO_REF:0000019, GO:0048169=GO_REF:0000019, GO:0007611=GO_REF:0000019, GO:0031667=GO_REF:0000019, GO:0035035=PMID:20018936, GO:0032869=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0030509=GO_REF:0000019, GO:0000979=GO_REF:0000019, GO:0071317=GO_REF:0000019, GO:0071383=GO_REF:0000019, GO:0007623=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_25192, GO:0071873=GO_REF:0000019, GO:0045893=PMID:12560508, GO:0008134=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0072110=GO_REF:0000024, GO:0005634=PMID:19057511, GO:0071480=GO_REF:0000019, GO:0071372=GO_REF:0000019, GO:0005737=PMID:19057511, GO:0045944=PMID:20018936, GO:0033233=PMID:19057511, GO:0090090=GO_REF:0000019, GO:0070498=PMID:20018936, GO:0071236=GO_REF:0000019, GO:0034465=GO_REF:0000019, GO:0071455=GO_REF:0000019, GO:0071456=GO_REF:0000019, GO:0035690=GO_REF:0000019, GO:0003677=PMID:12560508, GO:0009749=GO_REF:0000019, GO:0043565=PMID:1662794, GO:0001077=GO_REF:0000019, GO:0001975=GO_REF:0000019, GO:0030217=GO_REF:0000019, GO:0071363=GO_REF:0000019, GO:0071504=GO_REF:0000024, GO:0071506=GO_REF:0000024, GO:0071260=GO_REF:0000019, GO:0071320=GO_REF:0000019} P18146 Early growth response protein 1 protein 20110127 {GO:0005515=IPI, GO:0003700=IDA, GO:0006366=IDA, GO:0048709=IEA, GO:0019221=TAS, GO:0060291=IEA, GO:0042220=IEA, GO:0043525=IEA, GO:0003690=IEA, GO:0072303=ISS, GO:0060337=TAS, GO:0051602=IEA, GO:0048169=IEA, GO:0007611=IEA, GO:0031667=IEA, GO:0035035=IPI, GO:0032869=IEA, GO:0000122=IEA, GO:0030509=IEA, GO:0000979=IEA, GO:0071317=IEA, GO:0071383=IEA, GO:0007623=IEA, GO:0008270=IEA, GO:0005654=TAS, GO:0071873=IEA, GO:0045893=IDA, GO:0008134=IEA, GO:0045471=IEA, GO:0072110=ISS, GO:0005634=IDA, GO:0071480=IEA, GO:0071372=IEA, GO:0005737=IDA, GO:0045944=IMP, GO:0033233=IDA, GO:0090090=IEA, GO:0070498=IMP, GO:0071236=IEA, GO:0034465=IEA, GO:0071455=IEA, GO:0071456=IEA, GO:0035690=IEA, GO:0003677=IDA, GO:0009749=IEA, GO:0043565=IDA, GO:0001077=IEA, GO:0001975=IEA, GO:0030217=IEA, GO:0071363=IEA, GO:0071504=ISS, GO:0071506=ISS, GO:0071260=IEA, GO:0071320=IEA} BMP signaling pathway, T cell differentiation, cellular response to antibiotic, cellular response to cAMP, cellular response to drug, cellular response to follicle-stimulating hormone stimulus, cellular response to gamma radiation, cellular response to growth factor stimulus, cellular response to heparin, cellular response to hyperoxia, cellular response to hypoxia, cellular response to insulin stimulus, cellular response to isoquinoline alkaloid, cellular response to mechanical stimulus, cellular response to mycophenolic acid, cellular response to steroid hormone stimulus, circadian rhythm, cytokine-mediated signaling pathway, glomerular mesangial cell proliferation, interleukin-1-mediated signaling pathway, learning or memory, long-term synaptic potentiation, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, oligodendrocyte differentiation, positive regulation of glomerular metanephric mesangial cell proliferation, positive regulation of neuron apoptotic process, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of long-term neuronal synaptic plasticity, regulation of protein sumoylation, response to amphetamine, response to carbon monoxide, response to cocaine, response to electrical stimulus, response to ethanol, response to glucose stimulus, response to norepinephrine stimulus, response to nutrient levels, transcription from RNA polymerase II promoter, type I interferon-mediated signaling pathway cytoplasm, nucleoplasm, nucleus DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II core promoter sequence-specific DNA binding, double-stranded DNA binding, histone acetyltransferase binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, zinc ion binding Human EGR2 BHF-UCL UniProtKB {GO:0005515=PMID:14532282, GO:0003700=PMID:14532282, GO:0006366=GO_REF:0000024, GO:0044212=GO_REF:0000024, GO:0016874=GO_REF:0000037, GO:0005634=PMID:14532282, GO:0014037=GO_REF:0000019, GO:0005737=GO_REF:0000024, GO:0030278=GO_REF:0000019, GO:0021660=GO_REF:0000019, GO:0048168=GO_REF:0000019, GO:0035284=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0006611=GO_REF:0000024, GO:0007611=GO_REF:0000019, GO:0045444=GO_REF:0000024, GO:0031625=PMID:19651900, GO:0001102=GO_REF:0000024, GO:0032868=GO_REF:0000019, GO:0042552=GO_REF:0000019, GO:0071310=GO_REF:0000019, GO:0016925=GO_REF:0000041, GO:0021666=GO_REF:0000019, GO:0008045=GO_REF:0000019, GO:0007420=PMID:9537424, GO:0003682=GO_REF:0000024, GO:0007422=PMID:9537424, GO:0071837=GO_REF:0000019, GO:0007622=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0021612=GO_REF:0000019, GO:0045893=GO_REF:0000024} P11161 E3 SUMO-protein ligase EGR2 protein 20101220 {GO:0005515=IPI, GO:0003700=IDA, GO:0006366=ISS, GO:0044212=ISS, GO:0016874=IEA, GO:0005634=IC, GO:0014037=IEA, GO:0005737=ISS, GO:0030278=IEA, GO:0021660=IEA, GO:0048168=IEA, GO:0035284=IEA, GO:0045944=IEA, GO:0006611=ISS, GO:0007611=IEA, GO:0045444=ISS, GO:0031625=IPI, GO:0001102=ISS, GO:0032868=IEA, GO:0042552=IEA, GO:0071310=IEA, GO:0016925=IEA, GO:0021666=IEA, GO:0008045=IEA, GO:0007420=TAS, GO:0003682=ISS, GO:0007422=TAS, GO:0071837=IEA, GO:0007622=IEA, GO:0008270=IEA, GO:0021612=IEA, GO:0045893=ISS} Schwann cell differentiation, brain development, brain segmentation, cellular response to organic substance, facial nerve structural organization, fat cell differentiation, learning or memory, motor neuron axon guidance, myelination, peripheral nervous system development, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein export from nucleus, protein sumoylation, regulation of neuronal synaptic plasticity, regulation of ossification, response to insulin stimulus, rhombomere 3 formation, rhombomere 5 formation, rhythmic behavior, transcription from RNA polymerase II promoter cytoplasm, nucleus HMG box domain binding, RNA polymerase II activating transcription factor binding, chromatin binding, ligase activity, protein binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding, ubiquitin protein ligase binding, zinc ion binding Human GO:0003700 EGR3 PINC UniProtKB {GO:0007517=PMID:9731539, GO:0003700=PMID:9731539, GO:0007422=GO_REF:0000019, GO:0007623=PMID:9488654, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0007274=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q06889 Early growth response protein 3 protein 20030904 {GO:0007517=TAS, GO:0003700=TAS, GO:0007422=IEA, GO:0007623=TAS, GO:0005634=IEA, GO:0008270=IEA, GO:0007274=IEA, GO:0003677=IEA, GO:0006351=IEA} circadian rhythm, muscle organ development, neuromuscular synaptic transmission, peripheral nervous system development, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human EGR4 PINC UniProtKB {GO:0008284=PMID:1658795, GO:0003700=PMID:1584812, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q05215 Early growth response protein 4 protein 20030904 {GO:0008284=TAS, GO:0003700=NAS, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} positive regulation of cell proliferation, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human EHBP1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0016020=GO_REF:0000039} Q8NDI1 EH domain-binding protein 1 protein 20110516 {GO:0005737=IDA, GO:0016020=IEA} cytoplasm, membrane Human EHBP1L1 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q8N3D4 EH domain-binding protein 1-like protein 1 protein 20101022 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human EHD1 BHF-UCL UniProtKB {GO:0005515=PMID:17233914, GO:0005811=GO_REF:0000024, GO:0042632=GO_REF:0000024, GO:0048471=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0032456=PMID:17233914, GO:0005509=GO_REF:0000002, GO:0003924=GO_REF:0000002, GO:0030139=GO_REF:0000019, GO:0005525=GO_REF:0000002, GO:0010886=GO_REF:0000024, GO:0006886=PMID:15020713, GO:0005524=GO_REF:0000037, GO:0006897=GO_REF:0000019, GO:0034383=GO_REF:0000024, GO:0007596=Reactome:REACT_604, GO:0031901=PMID:15020713, GO:0016197=GO_REF:0000019, GO:0051260=PMID:17233914, GO:0031095=GO_REF:0000024, GO:0055038=PMID:15020713, GO:0010008=Reactome:REACT_25249, GO:0005769=GO_REF:0000019} Q9H4M9 EH domain-containing protein 1 protein 20091118 {GO:0005515=IPI, GO:0005811=ISS, GO:0042632=ISS, GO:0048471=IEA, GO:0005886=IEA, GO:0032456=IGI, GO:0005509=IEA, GO:0003924=IEA, GO:0030139=IEA, GO:0005525=IEA, GO:0010886=ISS, GO:0006886=IMP, GO:0005524=IEA, GO:0006897=IEA, GO:0034383=ISS, GO:0007596=TAS, GO:0031901=IDA, GO:0016197=IEA, GO:0051260=IPI, GO:0031095=ISS, GO:0055038=IDA, GO:0010008=TAS, GO:0005769=IEA} blood coagulation, cholesterol homeostasis, endocytic recycling, endocytosis, endosomal transport, intracellular protein transport, low-density lipoprotein particle clearance, positive regulation of cholesterol storage, protein homooligomerization early endosome, early endosome membrane, endocytic vesicle, endosome membrane, lipid particle, perinuclear region of cytoplasm, plasma membrane, platelet dense tubular network membrane, recycling endosome membrane ATP binding, GTP binding, GTPase activity, calcium ion binding, protein binding Human UniProtKB:Q9WVK4 EHD2 Reactome UniProtKB {GO:0005515=PMID:17233914, GO:0048471=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0019904=GO_REF:0000019, GO:0032456=PMID:17233914, GO:0003924=GO_REF:0000002, GO:0005634=PMID:10673336, GO:0003676=PMID:10673336, GO:0005525=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0006897=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0030866=GO_REF:0000019, GO:0055038=PMID:17233914, GO:0010008=Reactome:REACT_25249} Q9NZN4 EH domain-containing protein 2 protein 20101111 {GO:0005515=IPI, GO:0048471=IEA, GO:0005886=IEA, GO:0005509=IEA, GO:0019904=IEA, GO:0032456=IGI, GO:0003924=IEA, GO:0005634=TAS, GO:0003676=TAS, GO:0005525=IEA, GO:0005524=IEA, GO:0006897=IEA, GO:0007596=TAS, GO:0030866=IEA, GO:0055038=IDA, GO:0010008=TAS} blood coagulation, cortical actin cytoskeleton organization, endocytic recycling, endocytosis endosome membrane, nucleus, perinuclear region of cytoplasm, plasma membrane, recycling endosome membrane ATP binding, GTP binding, GTPase activity, calcium ion binding, nucleic acid binding, protein binding, protein domain specific binding Human EHD3 Reactome UniProtKB {GO:0005515=PMID:17233914, GO:0048471=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0072661=PMID:20489164, GO:0005509=GO_REF:0000002, GO:0032456=PMID:17233914, GO:0003924=GO_REF:0000002, GO:0005634=PMID:10673336, GO:0030139=GO_REF:0000019, GO:0005525=GO_REF:0000002, GO:0003676=PMID:10673336, GO:0005524=GO_REF:0000037, GO:0005737=GO_REF:0000024, GO:0007596=Reactome:REACT_604, GO:0051260=PMID:17233914, GO:0086036=PMID:20489164, GO:0055038=PMID:17233914, GO:0010008=Reactome:REACT_25249} Q9NZN3 EH domain-containing protein 3 protein 20101111 {GO:0005515=IPI, GO:0048471=IEA, GO:0005886=IEA, GO:0072661=IGI, GO:0005509=IEA, GO:0032456=IDA, GO:0003924=IEA, GO:0005634=TAS, GO:0030139=IEA, GO:0005525=IEA, GO:0003676=TAS, GO:0005524=IEA, GO:0005737=ISS, GO:0007596=TAS, GO:0051260=IPI, GO:0086036=IGI, GO:0055038=IDA, GO:0010008=TAS} blood coagulation, endocytic recycling, protein homooligomerization, protein targeting to plasma membrane, regulation of cardiac muscle cell membrane potential cytoplasm, endocytic vesicle, endosome membrane, nucleus, perinuclear region of cytoplasm, plasma membrane, recycling endosome membrane ATP binding, GTP binding, GTPase activity, calcium ion binding, nucleic acid binding, protein binding Human EHD4 LIFEdb UniProtKB {GO:0005515=PMID:17233914, GO:0006907=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0005783=GO_REF:0000054, GO:0032456=PMID:17233914, GO:0005509=GO_REF:0000002, GO:0003924=GO_REF:0000002, GO:0050731=GO_REF:0000019, GO:0005634=PMID:10673336, GO:0003676=PMID:10673336, GO:0005525=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0071363=GO_REF:0000019, GO:0030100=GO_REF:0000019, GO:0031901=GO_REF:0000039, GO:0051260=PMID:17233914, GO:0055038=PMID:17233914} Q9H223 EH domain-containing protein 4 protein 20100607 {GO:0005515=IPI, GO:0006907=IEA, GO:0048471=IEA, GO:0005886=IEA, GO:0005783=IDA, GO:0032456=IGI, GO:0005509=IEA, GO:0003924=IEA, GO:0050731=IEA, GO:0005634=TAS, GO:0003676=TAS, GO:0005525=IEA, GO:0005524=IEA, GO:0071363=IEA, GO:0030100=IEA, GO:0031901=IEA, GO:0051260=IPI, GO:0055038=IDA} cellular response to growth factor stimulus, endocytic recycling, pinocytosis, positive regulation of peptidyl-tyrosine phosphorylation, protein homooligomerization, regulation of endocytosis early endosome membrane, endoplasmic reticulum, nucleus, perinuclear region of cytoplasm, plasma membrane, recycling endosome membrane ATP binding, GTP binding, GTPase activity, calcium ion binding, nucleic acid binding, protein binding Human EHF UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=PMID:10644770, GO:0008283=PMID:10644770, GO:0030855=PMID:10644770, GO:0007275=PMID:10644770, GO:0005634=PMID:10644770, GO:0045893=PMID:10644770, GO:0003677=PMID:10644770, GO:0006351=GO_REF:0000037} Q9NZC4 ETS homologous factor protein 20061130 {GO:0043565=IEA, GO:0003700=IDA, GO:0008283=TAS, GO:0030855=IEP, GO:0007275=TAS, GO:0005634=IC, GO:0045893=IDA, GO:0003677=IDA, GO:0006351=IEA} cell proliferation, epithelial cell differentiation, multicellular organismal development, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human EHHADH HPA UniProtKB {GO:0050662=GO_REF:0000002, GO:0006635=PMID:8188243, GO:0005730=GO_REF:0000052, GO:0005102=PMID:20178365, GO:0003857=PMID:8188243, GO:0005634=GO_REF:0000052, GO:0003824=GO_REF:0000002, GO:0043231=GO_REF:0000052, GO:0005829=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0004165=GO_REF:0000003, GO:0006475=PMID:20167786, GO:0019899=PMID:16781659, GO:0004300=PMID:8188243, GO:0005777=PMID:8188243} Q08426 Peroxisomal bifunctional enzyme protein 20110516 {GO:0050662=IEA, GO:0006635=NAS, GO:0005730=IDA, GO:0005102=IPI, GO:0003857=NAS, GO:0005634=IDA, GO:0003824=IEA, GO:0043231=IDA, GO:0005829=IEA, GO:0005739=IEA, GO:0005737=IDA, GO:0004165=IEA, GO:0006475=IDA, GO:0019899=IPI, GO:0004300=NAS, GO:0005777=NAS} fatty acid beta-oxidation, internal protein amino acid acetylation cytoplasm, cytosol, intracellular membrane-bounded organelle, mitochondrion, nucleolus, nucleus, peroxisome 3-hydroxyacyl-CoA dehydrogenase activity, catalytic activity, coenzyme binding, dodecenoyl-CoA delta-isomerase activity, enoyl-CoA hydratase activity, enzyme binding, receptor binding Human EHMT1 IntAct UniProtKB {GO:0005515=PMID:21131967, GO:0005694=GO_REF:0000039, GO:0016571=PMID:12004135, GO:0008168=PMID:12004135, GO:0018027=PMID:20118233, GO:0005634=GO_REF:0000024, GO:0000122=GO_REF:0000019, GO:0009790=GO_REF:0000024, GO:0016279=PMID:20118233, GO:0018026=GO_REF:0000024, GO:0018024=PMID:12004135, GO:0006306=GO_REF:0000024, GO:0002039=PMID:20118233, GO:0046974=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0045892=GO_REF:0000024, GO:0046976=GO_REF:0000024, GO:0016568=PMID:12004135} Q9H9B1 Histone-lysine N-methyltransferase EHMT1 protein 20130415 {GO:0005515=IPI, GO:0005694=IEA, GO:0016571=IDA, GO:0008168=IDA, GO:0018027=IDA, GO:0005634=ISS, GO:0000122=IEA, GO:0009790=ISS, GO:0016279=IDA, GO:0018026=ISS, GO:0018024=IDA, GO:0006306=ISS, GO:0002039=IPI, GO:0046974=ISS, GO:0008270=IEA, GO:0045892=ISS, GO:0046976=ISS, GO:0016568=IDA} DNA methylation, chromatin modification, embryo development, histone methylation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, peptidyl-lysine dimethylation, peptidyl-lysine monomethylation chromosome, nucleus histone methyltransferase activity (H3-K27 specific), histone methyltransferase activity (H3-K9 specific), histone-lysine N-methyltransferase activity, methyltransferase activity, p53 binding, protein binding, protein-lysine N-methyltransferase activity, zinc ion binding Human UniProtKB:Q04207 EHMT2 IntAct UniProtKB {GO:0005515=PMID:17636019, GO:0000239=GO_REF:0000019, GO:0005694=GO_REF:0000039, GO:0016571=PMID:22387026, GO:0007286=GO_REF:0000019, GO:0010424=GO_REF:0000019, GO:0018027=PMID:20118233, GO:0005634=GO_REF:0000024, GO:0000122=GO_REF:0000019, GO:0016279=PMID:20118233, GO:0018024=PMID:22387026, GO:0006306=GO_REF:0000024, GO:0009566=GO_REF:0000019, GO:0002039=PMID:20118233, GO:0035265=GO_REF:0000019, GO:0046974=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0007130=GO_REF:0000019, GO:0006275=PMID:22387026, GO:0046976=GO_REF:0000024} Q96KQ7 Histone-lysine N-methyltransferase EHMT2 protein 20130415 {GO:0005515=IPI, GO:0000239=IEA, GO:0005694=IEA, GO:0016571=IMP, GO:0007286=IEA, GO:0010424=IEA, GO:0018027=IDA, GO:0005634=ISS, GO:0000122=IEA, GO:0016279=IDA, GO:0018024=IMP, GO:0006306=ISS, GO:0009566=IEA, GO:0002039=IPI, GO:0035265=IEA, GO:0046974=ISS, GO:0008270=IEA, GO:0007130=IEA, GO:0006275=IMP, GO:0046976=ISS} DNA methylation, DNA methylation on cytosine within a CG sequence, fertilization, histone methylation, negative regulation of transcription from RNA polymerase II promoter, organ growth, pachytene, peptidyl-lysine dimethylation, regulation of DNA replication, spermatid development, synaptonemal complex assembly chromosome, nucleus histone methyltransferase activity (H3-K27 specific), histone methyltransferase activity (H3-K9 specific), histone-lysine N-methyltransferase activity, p53 binding, protein binding, protein-lysine N-methyltransferase activity, zinc ion binding Human UniProtKB:Q9NQX1 EI24 MGI UniProtKB {GO:0030308=PMID:10594026, GO:0031965=GO_REF:0000039, GO:0042493=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0006914=GO_REF:0000037, GO:0006915=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0006917=GO_REF:0000019} O14681 Etoposide-induced protein 2.4 homolog protein 20080903 {GO:0030308=IDA, GO:0031965=IEA, GO:0042493=IEA, GO:0005789=IEA, GO:0006914=IEA, GO:0006915=IEA, GO:0016021=IEA, GO:0006917=IEA} apoptotic process, autophagy, induction of apoptosis, negative regulation of cell growth, response to drug endoplasmic reticulum membrane, integral to membrane, nuclear membrane Human EID1 GOC UniProtKB {GO:0035035=PMID:11073990, GO:0005515=PMID:18557765, GO:0005737=GO_REF:0000039, GO:0007049=GO_REF:0000037, GO:0035034=PMID:11073990, GO:0003714=GO_REF:0000024, GO:0035065=PMID:11073990, GO:0005634=PMID:11073990, GO:0000122=PMID:11073990, GO:0045892=PMID:11073990, GO:0030154=PMID:11073989, GO:0006351=GO_REF:0000037} Q9Y6B2 EP300-interacting inhibitor of differentiation 1 protein 20130413 {GO:0035035=IDA, GO:0005515=IPI, GO:0005737=IEA, GO:0007049=IEA, GO:0035034=IDA, GO:0003714=ISS, GO:0035065=IDA, GO:0005634=IPI, GO:0000122=IDA, GO:0045892=IDA, GO:0030154=IDA, GO:0006351=IEA} cell cycle, cell differentiation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, regulation of histone acetylation, transcription, DNA-dependent cytoplasm, nucleus histone acetyltransferase binding, histone acetyltransferase regulator activity, protein binding, transcription corepressor activity Human EID2 HPA UniProtKB {GO:0005515=PMID:15970276, GO:0005730=GO_REF:0000052, GO:0046332=PMID:14612439, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0005622=PMID:14612439, GO:0007183=PMID:14612439, GO:0007517=GO_REF:0000037, GO:0007181=PMID:14612439, GO:0042127=PMID:14612439, GO:0017015=PMID:14612439, GO:0045892=PMID:14612439, GO:0030512=PMID:14612439} Q8N6I1 EP300-interacting inhibitor of differentiation 2 protein 20111111 {GO:0005515=IPI, GO:0005730=IDA, GO:0046332=IDA, GO:0005634=IDA, GO:0006351=IEA, GO:0030154=IEA, GO:0005622=IC, GO:0007183=IDA, GO:0007517=IEA, GO:0007181=IDA, GO:0042127=IDA, GO:0017015=IDA, GO:0045892=IDA, GO:0030512=IDA} SMAD protein complex assembly, cell differentiation, muscle organ development, negative regulation of transcription, DNA-dependent, negative regulation of transforming growth factor beta receptor signaling pathway, regulation of cell proliferation, regulation of transforming growth factor beta receptor signaling pathway, transcription, DNA-dependent, transforming growth factor beta receptor complex assembly intracellular, nucleolus, nucleus SMAD binding, protein binding NOT Human EID2B UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0007517=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96D98 EP300-interacting inhibitor of differentiation 2B protein 20130413 {GO:0006355=IEA, GO:0007517=IEA, GO:0005634=IEA, GO:0030154=IEA, GO:0006351=IEA} cell differentiation, muscle organ development, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus Human UniProtKB-SubCell:SL-0191 EID3 IntAct UniProtKB {GO:0005515=PMID:21364888, GO:0005737=GO_REF:0000039, GO:0000781=GO_REF:0000039, GO:0006355=GO_REF:0000037, GO:0006281=GO_REF:0000037, GO:0030915=PMID:18086888, GO:0005634=GO_REF:0000039, GO:0006310=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0042802=PMID:15970276} Q8N140 EP300-interacting inhibitor of differentiation 3 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0000781=IEA, GO:0006355=IEA, GO:0006281=IEA, GO:0030915=IDA, GO:0005634=IEA, GO:0006310=IEA, GO:0006351=IEA, GO:0042802=IPI} DNA recombination, DNA repair, regulation of transcription, DNA-dependent, transcription, DNA-dependent Smc5-Smc6 complex, chromosome, telomeric region, cytoplasm, nucleus identical protein binding, protein binding Human UniProtKB:Q8N140 EIF1 PINC UniProtKB {GO:0005737=PMID:10347211, GO:0006446=PMID:10347211, GO:0006950=PMID:10347211, GO:0003743=PMID:10347211, GO:0008135=PMID:10347211, GO:0006413=GO_REF:0000029} P41567 Eukaryotic translation initiation factor 1 protein 20030904 {GO:0005737=TAS, GO:0006446=TAS, GO:0006950=NAS, GO:0003743=NAS, GO:0008135=TAS, GO:0006413=NAS} regulation of translational initiation, response to stress, translational initiation cytoplasm translation factor activity, nucleic acid binding, translation initiation factor activity Human EIF1AD UniProtKB UniProtKB {GO:0003743=GO_REF:0000002, GO:0005634=GO_REF:0000039} Q8N9N8 Probable RNA-binding protein EIF1AD protein 20130413 {GO:0003743=IEA, GO:0005634=IEA} nucleus translation initiation factor activity Human UniProtKB-SubCell:SL-0191 EIF1AX Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003743=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0008135=PMID:8106356, GO:0005829=Reactome:REACT_1904} P47813 Eukaryotic translation initiation factor 1A, X-chromosomal protein 20130213 {GO:0010467=TAS, GO:0003743=IEA, GO:0044267=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0008135=TAS, GO:0005829=TAS} cellular protein metabolic process, gene expression, translation, translational initiation cytosol translation factor activity, nucleic acid binding, translation initiation factor activity Human EIF1AY IntAct UniProtKB {GO:0005515=PMID:12569173, GO:0003743=GO_REF:0000037} O14602 Eukaryotic translation initiation factor 1A, Y-chromosomal protein 20130415 {GO:0005515=IPI, GO:0003743=IEA} protein binding, translation initiation factor activity Human UniProtKB:O60841 EIF1B UniProtKB UniProtKB {GO:0006446=PMID:7904817, GO:0003743=GO_REF:0000037, GO:0005575=GO_REF:0000015} O60739 Eukaryotic translation initiation factor 1b protein 20080924 {GO:0006446=NAS, GO:0003743=IEA, GO:0005575=ND} regulation of translational initiation cellular_component translation initiation factor activity Human EIF2A UniProtKB UniProtKB {GO:0005515=PMID:18816594, GO:0005850=PMID:12133843, GO:0005737=PMID:12133843, GO:0000049=PMID:12133843, GO:0032933=GO_REF:0000019, GO:0042255=PMID:12133843, GO:0043022=PMID:12133843, GO:0003743=PMID:12133843, GO:0009967=GO_REF:0000019, GO:0006468=GO_REF:0000019, GO:0006417=PMID:12133843} Q9BY44 Eukaryotic translation initiation factor 2A protein 20120223 {GO:0005515=IPI, GO:0005850=IDA, GO:0005737=IDA, GO:0000049=IMP, GO:0032933=IEA, GO:0042255=IMP, GO:0043022=IMP, GO:0003743=IMP, GO:0009967=IEA, GO:0006468=IEA, GO:0006417=IMP} SREBP signaling pathway, positive regulation of signal transduction, protein phosphorylation, regulation of translation, ribosome assembly cytoplasm, eukaryotic translation initiation factor 2 complex protein binding, ribosome binding, tRNA binding, translation initiation factor activity Human UniProtKB:Q14899 EIF2AK1 UniProtKB UniProtKB {GO:0008285=GO_REF:0000019, GO:0006950=PMID:11036079, GO:0003743=GO_REF:0000038, GO:0010999=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0042803=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0045993=PMID:11036079, GO:0009605=PMID:11036079, GO:0046777=GO_REF:0000024, GO:0004674=GO_REF:0000002, GO:0046986=GO_REF:0000024, GO:0046501=GO_REF:0000019, GO:0004694=PMID:11036079, GO:0020037=GO_REF:0000024} Q9BQI3 Eukaryotic translation initiation factor 2-alpha kinase 1 protein 20041006 {GO:0008285=IEA, GO:0006950=IEP, GO:0003743=IEA, GO:0010999=IEA, GO:0005524=IEA, GO:0042803=ISS, GO:0005737=IEA, GO:0045993=NAS, GO:0009605=IEP, GO:0046777=ISS, GO:0004674=IEA, GO:0046986=ISS, GO:0046501=IEA, GO:0004694=IDA, GO:0020037=ISS} negative regulation of cell proliferation, negative regulation of hemoglobin biosynthetic process, negative regulation of translational initiation by iron, protein autophosphorylation, protoporphyrinogen IX metabolic process, regulation of eIF2 alpha phosphorylation by heme, response to external stimulus, response to stress cytoplasm ATP binding, eukaryotic translation initiation factor 2alpha kinase activity, heme binding, protein homodimerization activity, protein serine/threonine kinase activity, translation initiation factor activity Human UniProtKB:Q9Z2R9 EIF2AK2 IntAct UniProtKB {GO:0005515=PMID:23455922, GO:0003725=GO_REF:0000019, GO:0033689=PMID:16216244, GO:0008285=PMID:1351683, GO:0019054=Reactome:REACT_6222, GO:0008601=PMID:10866685, GO:0019058=Reactome:REACT_6167, GO:0006926=GO_REF:0000019, GO:0006412=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_6186, GO:0030968=GO_REF:0000019, GO:0051607=GO_REF:0000037, GO:0004672=GO_REF:0000019, GO:0046777=PMID:16216244, GO:0004674=PMID:1695551, GO:0019048=Reactome:REACT_6323, GO:0030683=Reactome:REACT_6350, GO:0006468=PMID:1695551, GO:0004715=GO_REF:0000003, GO:0004694=PMID:10866685} P19525 Interferon-induced, double-stranded RNA-activated protein kinase protein 20130415 {GO:0005515=IPI, GO:0003725=IEA, GO:0033689=IMP, GO:0008285=TAS, GO:0019054=TAS, GO:0008601=TAS, GO:0019058=TAS, GO:0006926=IEA, GO:0006412=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0030968=IEA, GO:0051607=IEA, GO:0004672=IEA, GO:0046777=IMP, GO:0004674=TAS, GO:0019048=TAS, GO:0030683=TAS, GO:0006468=TAS, GO:0004715=IEA, GO:0004694=TAS} defense response to virus, endoplasmic reticulum unfolded protein response, evasion or tolerance by virus of host immune response, modulation by virus of host cellular process, negative regulation of cell proliferation, negative regulation of osteoblast proliferation, protein autophosphorylation, protein phosphorylation, translation, viral infectious cycle, virus-host interaction, virus-infected cell apoptotic process cytosol ATP binding, double-stranded RNA binding, eukaryotic translation initiation factor 2alpha kinase activity, non-membrane spanning protein tyrosine kinase activity, protein binding, protein kinase activity, protein phosphatase type 2A regulator activity, protein serine/threonine kinase activity Human UniProtKB:Q7L2E3 EIF2AK3 BHF-UCL UniProtKB {GO:0017148=PMID:12086964, GO:0005515=PMID:11907036, GO:0032055=GO_REF:0000019, GO:0034976=PMID:19061639, GO:0019722=GO_REF:0000024, GO:0006983=PMID:10677345, GO:0005783=GO_REF:0000024, GO:0006926=GO_REF:0000019, GO:0030282=GO_REF:0000024, GO:0006412=GO_REF:0000019, GO:0042802=PMID:11907036, GO:0030968=PMID:19816510, GO:0032092=GO_REF:0000019, GO:0005737=GO_REF:0000024, GO:0032933=GO_REF:0000019, GO:0046777=PMID:12086964, GO:0002063=GO_REF:0000024, GO:0045444=GO_REF:0000019, GO:0051260=PMID:11907036, GO:0031642=GO_REF:0000024, GO:0006919=GO_REF:0000024, GO:0019903=PMID:22169477, GO:0009967=GO_REF:0000019, GO:0019217=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0032057=PMID:19816510, GO:0001501=GO_REF:0000024, GO:0004672=PMID:10026192, GO:0007595=GO_REF:0000019, GO:0001503=PMID:12086964, GO:0031016=GO_REF:0000019, GO:0004674=Reactome:REACT_18275, GO:0031018=PMID:12086964, GO:0005789=Reactome:REACT_18413, GO:0006468=GO_REF:0000024, GO:0048009=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0006987=Reactome:REACT_18277, GO:0044267=Reactome:REACT_17015, GO:0030073=GO_REF:0000024, GO:0007029=GO_REF:0000024, GO:0004694=PMID:12086964} Q9NZJ5 Eukaryotic translation initiation factor 2-alpha kinase 3 protein 20100107 {GO:0017148=TAS, GO:0005515=IPI, GO:0032055=IEA, GO:0034976=IMP, GO:0019722=ISS, GO:0006983=IDA, GO:0005783=ISS, GO:0006926=IEA, GO:0030282=ISS, GO:0006412=IEA, GO:0042802=IPI, GO:0030968=TAS, GO:0032092=IEA, GO:0005737=ISS, GO:0032933=IEA, GO:0046777=IMP, GO:0002063=ISS, GO:0045444=IEA, GO:0051260=IMP, GO:0031642=ISS, GO:0006919=ISS, GO:0019903=IPI, GO:0009967=IEA, GO:0019217=IEA, GO:0005524=IEA, GO:0032057=TAS, GO:0001501=ISS, GO:0004672=TAS, GO:0007595=IEA, GO:0001503=IMP, GO:0031016=IEA, GO:0004674=TAS, GO:0031018=IMP, GO:0005789=TAS, GO:0006468=ISS, GO:0048009=ISS, GO:0016021=IEA, GO:0006987=TAS, GO:0044267=TAS, GO:0030073=ISS, GO:0007029=ISS, GO:0004694=IMP} ER overload response, SREBP signaling pathway, activation of cysteine-type endopeptidase activity involved in apoptotic process, activation of signaling protein activity involved in unfolded protein response, bone mineralization, calcium-mediated signaling, cellular protein metabolic process, chondrocyte development, endocrine pancreas development, endoplasmic reticulum organization, endoplasmic reticulum unfolded protein response, fat cell differentiation, insulin secretion, insulin-like growth factor receptor signaling pathway, lactation, negative regulation of myelination, negative regulation of translation, negative regulation of translation in response to stress, negative regulation of translational initiation in response to stress, ossification, pancreas development, positive regulation of protein binding, positive regulation of signal transduction, protein autophosphorylation, protein homooligomerization, protein phosphorylation, regulation of fatty acid metabolic process, response to endoplasmic reticulum stress, skeletal system development, translation, virus-infected cell apoptotic process cytoplasm, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane ATP binding, eukaryotic translation initiation factor 2alpha kinase activity, identical protein binding, protein binding, protein kinase activity, protein phosphatase binding, protein serine/threonine kinase activity Human EIF2AK4 UniProtKB UniProtKB {GO:0005622=GO_REF:0000029, GO:0017148=GO_REF:0000019, GO:0043558=GO_REF:0000019, GO:0022626=GO_REF:0000024, GO:0004674=GO_REF:0000024, GO:0006446=GO_REF:0000024, GO:0006468=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0042803=GO_REF:0000002, GO:0004694=PMID:10504407, GO:0030968=GO_REF:0000019, GO:0009267=GO_REF:0000019} Q9P2K8 Eukaryotic translation initiation factor 2-alpha kinase 4 protein 20051108 {GO:0005622=NAS, GO:0017148=IEA, GO:0043558=IEA, GO:0022626=ISS, GO:0004674=ISS, GO:0006446=ISS, GO:0006468=ISS, GO:0005524=IEA, GO:0042803=IEA, GO:0004694=ISS, GO:0030968=IEA, GO:0009267=IEA} cellular response to starvation, endoplasmic reticulum unfolded protein response, negative regulation of translation, protein phosphorylation, regulation of translational initiation, regulation of translational initiation in response to stress cytosolic ribosome, intracellular ATP binding, eukaryotic translation initiation factor 2alpha kinase activity, protein homodimerization activity, protein serine/threonine kinase activity Human UniProtKB:Q9QZ05 EIF2B1 IntAct UniProtKB {GO:0005515=PMID:9235896, GO:0005851=PMID:11323413, GO:0010467=Reactome:REACT_71, GO:0051716=PMID:8626696, GO:0005886=PMID:9235896, GO:0009408=GO_REF:0000024, GO:0043434=GO_REF:0000024, GO:0003743=PMID:16289705, GO:0005525=GO_REF:0000019, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1401, GO:0009749=GO_REF:0000024, GO:0005085=PMID:11323413, GO:0032057=GO_REF:0000019, GO:0005737=PMID:9235896, GO:0016020=PMID:9235896, GO:0019509=GO_REF:0000033, GO:0014003=PMID:15217090, GO:0006446=GO_REF:0000033, GO:0019003=GO_REF:0000019, GO:0044267=Reactome:REACT_17015, GO:0044237=GO_REF:0000002, GO:0046523=GO_REF:0000033} Q14232 Translation initiation factor eIF-2B subunit alpha protein 20130415 {GO:0005515=IPI, GO:0005851=IDA, GO:0010467=TAS, GO:0051716=IDA, GO:0005886=IDA, GO:0009408=ISS, GO:0043434=ISS, GO:0003743=IDA, GO:0005525=IEA, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0009749=ISS, GO:0005085=IDA, GO:0032057=IEA, GO:0005737=IDA, GO:0016020=IDA, GO:0019509=IBA, GO:0014003=IMP, GO:0006446=IBA, GO:0019003=IEA, GO:0044267=TAS, GO:0044237=IEA, GO:0046523=IBA} L-methionine salvage from methylthioadenosine, cellular metabolic process, cellular protein metabolic process, cellular response to stimulus, gene expression, negative regulation of translational initiation in response to stress, oligodendrocyte development, regulation of translational initiation, response to glucose stimulus, response to heat, response to peptide hormone stimulus, translation, translational initiation cytoplasm, cytosol, eukaryotic translation initiation factor 2B complex, membrane, plasma membrane GDP binding, GTP binding, S-methyl-5-thioribose-1-phosphate isomerase activity, guanyl-nucleotide exchange factor activity, protein binding, translation initiation factor activity Human UniProtKB:Q01338 EIF2B2 Reactome UniProtKB {GO:0005851=PMID:11323413, GO:0005515=PMID:15060152, GO:0010467=Reactome:REACT_71, GO:0051716=PMID:8626696, GO:0009408=GO_REF:0000024, GO:0042552=PMID:14566705, GO:0003743=PMID:16289705, GO:0043434=GO_REF:0000024, GO:0007417=PMID:15776425, GO:0005525=PMID:11323413, GO:0006412=Reactome:REACT_1014, GO:0005524=PMID:11323413, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1401, GO:0009749=GO_REF:0000024, GO:0005085=PMID:11323413, GO:0001541=PMID:15507143, GO:0005737=PMID:11323413, GO:0019509=GO_REF:0000033, GO:0014003=PMID:15217090, GO:0006446=PMID:15060152, GO:0044267=Reactome:REACT_17015, GO:0044237=GO_REF:0000002, GO:0046523=GO_REF:0000033} P49770 Translation initiation factor eIF-2B subunit beta protein 20130213 {GO:0005851=IDA, GO:0005515=IPI, GO:0010467=TAS, GO:0051716=IDA, GO:0009408=ISS, GO:0042552=IMP, GO:0003743=IDA, GO:0043434=ISS, GO:0007417=IMP, GO:0005525=IDA, GO:0006412=TAS, GO:0005524=IDA, GO:0006413=TAS, GO:0005829=TAS, GO:0009749=ISS, GO:0005085=IDA, GO:0001541=IMP, GO:0005737=IDA, GO:0019509=IBA, GO:0014003=IMP, GO:0006446=TAS, GO:0044267=TAS, GO:0044237=IEA, GO:0046523=IBA} L-methionine salvage from methylthioadenosine, cellular metabolic process, cellular protein metabolic process, cellular response to stimulus, central nervous system development, gene expression, myelination, oligodendrocyte development, ovarian follicle development, regulation of translational initiation, response to glucose stimulus, response to heat, response to peptide hormone stimulus, translation, translational initiation cytoplasm, cytosol, eukaryotic translation initiation factor 2B complex ATP binding, GTP binding, S-methyl-5-thioribose-1-phosphate isomerase activity, guanyl-nucleotide exchange factor activity, protein binding, translation initiation factor activity Human EIF2B3 Reactome UniProtKB {GO:0005515=PMID:15060152, GO:0005851=PMID:11323413, GO:0010467=Reactome:REACT_71, GO:0051716=PMID:8626696, GO:0009408=GO_REF:0000024, GO:0009058=GO_REF:0000002, GO:0016779=GO_REF:0000002, GO:0003743=PMID:16289705, GO:0043434=GO_REF:0000024, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1401, GO:0009749=GO_REF:0000024, GO:0005085=PMID:11323413, GO:0032057=GO_REF:0000024, GO:0005737=PMID:11323413, GO:0014003=PMID:15217090, GO:0044267=Reactome:REACT_17015, GO:0016740=GO_REF:0000002, GO:0008135=PMID:10900014} Q9NR50 Translation initiation factor eIF-2B subunit gamma protein 20130213 {GO:0005515=IPI, GO:0005851=IDA, GO:0010467=TAS, GO:0051716=IDA, GO:0009408=ISS, GO:0009058=IEA, GO:0016779=IEA, GO:0003743=IDA, GO:0043434=ISS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0009749=ISS, GO:0005085=IDA, GO:0032057=ISS, GO:0005737=IDA, GO:0014003=IMP, GO:0044267=TAS, GO:0016740=IEA, GO:0008135=IDA} biosynthetic process, cellular protein metabolic process, cellular response to stimulus, gene expression, negative regulation of translational initiation in response to stress, oligodendrocyte development, response to glucose stimulus, response to heat, response to peptide hormone stimulus, translation, translational initiation cytoplasm, cytosol, eukaryotic translation initiation factor 2B complex guanyl-nucleotide exchange factor activity, nucleotidyltransferase activity, protein binding, transferase activity, translation factor activity, nucleic acid binding, translation initiation factor activity Human EIF2B4 Reactome UniProtKB {GO:0005515=PMID:15060152, GO:0010467=Reactome:REACT_71, GO:0051716=PMID:8626696, GO:0009408=GO_REF:0000024, GO:0003743=PMID:16289705, GO:0043434=GO_REF:0000024, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1401, GO:0005085=PMID:11323413, GO:0005737=PMID:11323413, GO:0001541=PMID:15507143, GO:0019509=GO_REF:0000033, GO:0045947=GO_REF:0000033, GO:0044237=GO_REF:0000002, GO:0005851=PMID:11323413, GO:0042552=PMID:14566705, GO:0006417=PMID:12556349, GO:0009749=GO_REF:0000024, GO:0032057=GO_REF:0000024, GO:0014003=PMID:15217090, GO:0006446=GO_REF:0000033, GO:0031369=GO_REF:0000024, GO:0044267=Reactome:REACT_17015, GO:0046523=GO_REF:0000033} Q9UI10 Translation initiation factor eIF-2B subunit delta protein 20130213 {GO:0005515=IPI, GO:0010467=TAS, GO:0051716=IDA, GO:0009408=ISS, GO:0003743=IDA, GO:0043434=ISS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0005085=IDA, GO:0005737=IDA, GO:0001541=IMP, GO:0019509=IBA, GO:0045947=IBA, GO:0044237=IEA, GO:0005851=IDA, GO:0042552=IMP, GO:0006417=NAS, GO:0009749=ISS, GO:0032057=ISS, GO:0014003=IMP, GO:0006446=IBA, GO:0031369=ISS, GO:0044267=TAS, GO:0046523=IBA} L-methionine salvage from methylthioadenosine, cellular metabolic process, cellular protein metabolic process, cellular response to stimulus, gene expression, myelination, negative regulation of translational initiation, negative regulation of translational initiation in response to stress, oligodendrocyte development, ovarian follicle development, regulation of translation, regulation of translational initiation, response to glucose stimulus, response to heat, response to peptide hormone stimulus, translation, translational initiation cytoplasm, cytosol, eukaryotic translation initiation factor 2B complex S-methyl-5-thioribose-1-phosphate isomerase activity, guanyl-nucleotide exchange factor activity, protein binding, translation initiation factor activity, translation initiation factor binding Human EIF2B5 Reactome UniProtKB {GO:0005515=PMID:15060152, GO:0010467=Reactome:REACT_71, GO:0051716=PMID:8626696, GO:0009408=GO_REF:0000024, GO:0048708=PMID:15723074, GO:0003743=PMID:16289705, GO:0043434=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1401, GO:0005085=GO_REF:0000024, GO:0001541=PMID:15507143, GO:0005737=PMID:11323413, GO:0045948=GO_REF:0000024, GO:0005851=PMID:11323413, GO:0016070=GO_REF:0000002, GO:0042552=PMID:15723074, GO:0006950=PMID:16041584, GO:0009749=GO_REF:0000024, GO:0032057=GO_REF:0000024, GO:0014002=PMID:15723074, GO:0014003=PMID:15217090, GO:0031369=GO_REF:0000024, GO:0044267=Reactome:REACT_17015, GO:0016740=GO_REF:0000002} Q13144 Translation initiation factor eIF-2B subunit epsilon protein 20130213 {GO:0005515=IPI, GO:0010467=TAS, GO:0051716=IDA, GO:0009408=ISS, GO:0048708=IMP, GO:0003743=IDA, GO:0043434=ISS, GO:0005634=ISS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0005085=ISS, GO:0001541=IMP, GO:0005737=IDA, GO:0045948=ISS, GO:0005851=IDA, GO:0016070=IEA, GO:0042552=IMP, GO:0006950=IMP, GO:0009749=ISS, GO:0032057=ISS, GO:0014002=IMP, GO:0014003=IMP, GO:0031369=ISS, GO:0044267=TAS, GO:0016740=IEA} RNA metabolic process, astrocyte development, astrocyte differentiation, cellular protein metabolic process, cellular response to stimulus, gene expression, myelination, negative regulation of translational initiation in response to stress, oligodendrocyte development, ovarian follicle development, positive regulation of translational initiation, response to glucose stimulus, response to heat, response to peptide hormone stimulus, response to stress, translation, translational initiation cytoplasm, cytosol, eukaryotic translation initiation factor 2B complex, nucleus guanyl-nucleotide exchange factor activity, protein binding, transferase activity, translation initiation factor activity, translation initiation factor binding Human EIF2D InterPro UniProtKB {GO:0005737=PMID:20566627, GO:0003723=GO_REF:0000002, GO:0003743=PMID:20566627, GO:0004872=PMID:2482295, GO:0006886=PMID:2482295} Q5SY38 Eukaryotic translation initiation factor 2D protein 20130413 {GO:0005737=IDA, GO:0003723=IEA, GO:0003743=IDA, GO:0004872=TAS, GO:0006886=TAS} intracellular protein transport cytoplasm RNA binding, receptor activity, translation initiation factor activity Human InterPro:IPR002478 EIF2S1 IntAct UniProtKB {GO:0005851=PMID:11323413, GO:0005515=PMID:22323517, GO:0010467=Reactome:REACT_71, GO:0005850=GO_REF:0000002, GO:0010494=GO_REF:0000024, GO:0003743=PMID:16289705, GO:0005634=GO_REF:0000019, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0030968=Reactome:REACT_18356, GO:0005829=Reactome:REACT_18275, GO:0043558=GO_REF:0000019, GO:0046777=GO_REF:0000019, GO:0043022=PMID:17894550, GO:0006987=Reactome:REACT_18277, GO:0044267=Reactome:REACT_17015, GO:0005844=PMID:2948954} P05198 Eukaryotic translation initiation factor 2 subunit 1 protein 20130415 {GO:0005851=IDA, GO:0005515=IPI, GO:0010467=TAS, GO:0005850=IEA, GO:0010494=ISS, GO:0003743=IDA, GO:0005634=IEA, GO:0006412=TAS, GO:0006413=TAS, GO:0030968=TAS, GO:0005829=TAS, GO:0043558=IEA, GO:0046777=IEA, GO:0043022=IDA, GO:0006987=TAS, GO:0044267=TAS, GO:0005844=TAS} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, gene expression, protein autophosphorylation, regulation of translational initiation in response to stress, translation, translational initiation cytoplasmic stress granule, cytosol, eukaryotic translation initiation factor 2 complex, eukaryotic translation initiation factor 2B complex, nucleus, polysome protein binding, ribosome binding, translation initiation factor activity Human UniProtKB:O00571 EIF2S2 IntAct UniProtKB {GO:0005515=PMID:16288713, GO:0010467=Reactome:REACT_71, GO:0005850=PMID:3044606, GO:0003723=PMID:3044606, GO:0003743=PMID:16289705, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0008135=PMID:3044606, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_1904} P20042 Eukaryotic translation initiation factor 2 subunit 2 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0005850=TAS, GO:0003723=TAS, GO:0003743=IDA, GO:0044267=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0008135=TAS, GO:0046872=IEA, GO:0005829=TAS} cellular protein metabolic process, gene expression, translation, translational initiation cytosol, eukaryotic translation initiation factor 2 complex RNA binding, metal ion binding, protein binding, translation factor activity, nucleic acid binding, translation initiation factor activity Human UniProtKB:P41091 EIF2S3 GOC UniProtKB {GO:0006184=PMID:8106381, GO:0005515=PMID:16288713, GO:0010467=Reactome:REACT_71, GO:0003924=GO_REF:0000002, GO:0003743=PMID:10900014, GO:0005525=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0008135=PMID:10900014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1904} P41091 Eukaryotic translation initiation factor 2 subunit 3 protein 20130413 {GO:0006184=TAS, GO:0005515=IPI, GO:0010467=TAS, GO:0003924=IEA, GO:0003743=IDA, GO:0005525=IEA, GO:0044267=TAS, GO:0006412=TAS, GO:0008135=IDA, GO:0006413=TAS, GO:0005829=TAS} GTP catabolic process, cellular protein metabolic process, gene expression, translation, translational initiation cytosol GTP binding, GTPase activity, protein binding, translation factor activity, nucleic acid binding, translation initiation factor activity Human EIF3A HPA UniProtKB {GO:0005515=PMID:22190034, GO:0010467=Reactome:REACT_71, GO:0005852=PMID:17322308, GO:0001732=PMID:17581632, GO:0005730=GO_REF:0000052, GO:0003743=PMID:17581632, GO:0005634=GO_REF:0000052, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1904, GO:0005737=GO_REF:0000052, GO:0005198=PMID:9150439, GO:0044267=Reactome:REACT_17015} Q14152 Eukaryotic translation initiation factor 3 subunit A protein 20110516 {GO:0005515=IPI, GO:0010467=TAS, GO:0005852=IDA, GO:0001732=IDA, GO:0005730=IDA, GO:0003743=IDA, GO:0005634=IDA, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0005198=NAS, GO:0044267=TAS} cellular protein metabolic process, formation of translation initiation complex, gene expression, translation, translational initiation cytoplasm, cytosol, eukaryotic translation initiation factor 3 complex, nucleolus, nucleus protein binding, structural molecule activity, translation initiation factor activity Human EIF3B Reactome UniProtKB {GO:0005515=PMID:18599441, GO:0010467=Reactome:REACT_71, GO:0032947=PMID:17322308, GO:0005852=PMID:17581632, GO:0000166=GO_REF:0000002, GO:0006446=PMID:8995410, GO:0003743=PMID:18599441, GO:0031369=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1904} P55884 Eukaryotic translation initiation factor 3 subunit B protein 20130213 {GO:0005515=IPI, GO:0010467=TAS, GO:0032947=TAS, GO:0005852=IDA, GO:0000166=IEA, GO:0006446=IDA, GO:0003743=IC, GO:0031369=IEA, GO:0044267=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS} cellular protein metabolic process, gene expression, regulation of translational initiation, translation, translational initiation cytosol, eukaryotic translation initiation factor 3 complex nucleotide binding, protein binding, protein complex scaffold, translation initiation factor activity, translation initiation factor binding Human EIF3C IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0010467=Reactome:REACT_71, GO:0005852=PMID:17322308, GO:0003743=PMID:17322308, GO:0031369=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1904} Q99613 Eukaryotic translation initiation factor 3 subunit C protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0005852=IDA, GO:0003743=IC, GO:0031369=IEA, GO:0044267=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS} cellular protein metabolic process, gene expression, translation, translational initiation cytosol, eukaryotic translation initiation factor 3 complex protein binding, translation initiation factor activity, translation initiation factor binding Human UniProtKB:Q9Q2G4 EIF3CL UniProtKB UniProtKB {GO:0005852=GO_REF:0000002, GO:0003743=GO_REF:0000038, GO:0031369=GO_REF:0000002} B5ME19 Eukaryotic translation initiation factor 3 subunit C protein 20130413 {GO:0005852=IEA, GO:0003743=IEA, GO:0031369=IEA} eukaryotic translation initiation factor 3 complex translation initiation factor activity, translation initiation factor binding Human UniProtKB-KW:KW-0396 EIF3D IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0010467=Reactome:REACT_71, GO:0005852=PMID:18599441, GO:0001732=GO_REF:0000019, GO:0003743=PMID:18599441, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1904} O15371 Eukaryotic translation initiation factor 3 subunit D protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0005852=IDA, GO:0001732=IEA, GO:0003743=IC, GO:0044267=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS} cellular protein metabolic process, formation of translation initiation complex, gene expression, translation, translational initiation cytosol, eukaryotic translation initiation factor 3 complex protein binding, translation initiation factor activity Human UniProtKB:Q9Q2G4 EIF3E HPA UniProtKB {GO:0005515=PMID:22190034, GO:0010467=Reactome:REACT_71, GO:0005852=PMID:10504338, GO:0003743=PMID:17322308, GO:0005634=GO_REF:0000052, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1904, GO:0005737=GO_REF:0000052, GO:0047485=PMID:10504338, GO:0000184=PMID:17468741, GO:0016605=PMID:10504338, GO:0006446=PMID:17468741, GO:0045947=PMID:10504338, GO:0005654=PMID:17468741, GO:0044267=Reactome:REACT_17015, GO:0000785=PMID:17468741} P60228 Eukaryotic translation initiation factor 3 subunit E protein 20101115 {GO:0005515=IPI, GO:0010467=TAS, GO:0005852=NAS, GO:0003743=IC, GO:0005634=IDA, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0047485=IPI, GO:0000184=IMP, GO:0016605=IDA, GO:0006446=NAS, GO:0045947=NAS, GO:0005654=NAS, GO:0044267=TAS, GO:0000785=NAS} cellular protein metabolic process, gene expression, negative regulation of translational initiation, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, regulation of translational initiation, translation, translational initiation PML body, chromatin, cytoplasm, cytosol, eukaryotic translation initiation factor 3 complex, nucleoplasm, nucleus protein N-terminus binding, protein binding, translation initiation factor activity Human EIF3F IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0010467=Reactome:REACT_71, GO:0005852=PMID:17581632, GO:0006508=GO_REF:0000037, GO:0003743=PMID:17581632, GO:0008234=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1904} O00303 Eukaryotic translation initiation factor 3 subunit F protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0005852=IDA, GO:0006508=IEA, GO:0003743=IDA, GO:0008234=IEA, GO:0044267=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS} cellular protein metabolic process, gene expression, proteolysis, translation, translational initiation cytosol, eukaryotic translation initiation factor 3 complex cysteine-type peptidase activity, protein binding, translation initiation factor activity Human UniProtKB:Q9Q2G4 EIF3G Reactome UniProtKB {GO:0005515=PMID:17094969, GO:0010467=Reactome:REACT_71, GO:0048471=GO_REF:0000039, GO:0005852=PMID:18599441, GO:0000166=GO_REF:0000002, GO:0003743=PMID:18599441, GO:0005634=GO_REF:0000039, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1904} O75821 Eukaryotic translation initiation factor 3 subunit G protein 20130213 {GO:0005515=IPI, GO:0010467=TAS, GO:0048471=IEA, GO:0005852=IDA, GO:0000166=IEA, GO:0003743=IC, GO:0005634=IEA, GO:0044267=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS} cellular protein metabolic process, gene expression, translation, translational initiation cytosol, eukaryotic translation initiation factor 3 complex, nucleus, perinuclear region of cytoplasm nucleotide binding, protein binding, translation initiation factor activity Human EIF3H HPA UniProtKB {GO:0005515=PMID:22190034, GO:0010467=Reactome:REACT_71, GO:0005737=GO_REF:0000052, GO:0005852=PMID:18599441, GO:0006446=PMID:9341143, GO:0003743=PMID:18599441, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1904} O15372 Eukaryotic translation initiation factor 3 subunit H protein 20100326 {GO:0005515=IPI, GO:0010467=TAS, GO:0005737=IDA, GO:0005852=IDA, GO:0006446=TAS, GO:0003743=IC, GO:0044267=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS} cellular protein metabolic process, gene expression, regulation of translational initiation, translation, translational initiation cytoplasm, cytosol, eukaryotic translation initiation factor 3 complex protein binding, translation initiation factor activity Human EIF3I ENSEMBL UniProtKB {GO:0010467=Reactome:REACT_71, GO:0005852=GO_REF:0000019, GO:0003743=PMID:17581632, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0006413=GO_REF:0000019, GO:0005829=Reactome:REACT_1904} Q5TFK1 Eukaryotic translation initiation factor 3 subunit I protein 20130413 {GO:0010467=TAS, GO:0005852=IEA, GO:0003743=IDA, GO:0044267=TAS, GO:0006412=TAS, GO:0006413=IEA, GO:0005829=TAS} cellular protein metabolic process, gene expression, translation, translational initiation cytosol, eukaryotic translation initiation factor 3 complex translation initiation factor activity Human Ensembl:ENSMUSP00000099653 EIF3J Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0005852=PMID:18599441, GO:0003743=PMID:18599441, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1904} O75822 Eukaryotic translation initiation factor 3 subunit J protein 20080912 {GO:0010467=TAS, GO:0005852=IDA, GO:0003743=IC, GO:0044267=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS} cellular protein metabolic process, gene expression, translation, translational initiation cytosol, eukaryotic translation initiation factor 3 complex translation initiation factor activity Human EIF3K HPA UniProtKB {GO:0005515=PMID:22190034, GO:0010467=Reactome:REACT_71, GO:0005852=PMID:17322308, GO:0006446=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0003743=PMID:17322308, GO:0043022=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1904} Q9UBQ5 Eukaryotic translation initiation factor 3 subunit K protein 20111111 {GO:0005515=IPI, GO:0010467=TAS, GO:0005852=IDA, GO:0006446=IEA, GO:0005730=IDA, GO:0003743=IC, GO:0043022=IEA, GO:0005634=IDA, GO:0044267=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS} cellular protein metabolic process, gene expression, regulation of translational initiation, translation, translational initiation cytosol, eukaryotic translation initiation factor 3 complex, nucleolus, nucleus protein binding, ribosome binding, translation initiation factor activity NOT Human EIF3L IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0005852=PMID:17322308, GO:0001650=GO_REF:0000019, GO:0003743=PMID:17322308, GO:0005654=GO_REF:0000019, GO:0006413=PMID:17322308} Q9Y262 Eukaryotic translation initiation factor 3 subunit L protein 20130415 {GO:0005515=IPI, GO:0005852=IDA, GO:0001650=IEA, GO:0003743=IC, GO:0005654=IEA, GO:0006413=IC} translational initiation eukaryotic translation initiation factor 3 complex, fibrillar center, nucleoplasm protein binding, translation initiation factor activity Human UniProtKB:Q9Q2G4 EIF3M IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0005852=PMID:17322308, GO:0003743=PMID:17322308, GO:0006413=PMID:17322308} Q7L2H7 Eukaryotic translation initiation factor 3 subunit M protein 20130415 {GO:0005515=IPI, GO:0005852=IDA, GO:0003743=IC, GO:0006413=IC} translational initiation eukaryotic translation initiation factor 3 complex protein binding, translation initiation factor activity Human UniProtKB:Q9Q2G4 EIF4A1 IntAct UniProtKB {GO:0008026=GO_REF:0000002, GO:0000339=PMID:3215517, GO:0005515=PMID:19203580, GO:0010467=Reactome:REACT_71, GO:0016281=PMID:9168945, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019221=Reactome:REACT_25229, GO:0004386=PMID:3215517, GO:0003743=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0003729=PMID:3215517, GO:0006412=Reactome:REACT_1014, GO:0005524=GO_REF:0000037, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115968, GO:0019048=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0008135=PMID:3215517, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639} P60842 Eukaryotic initiation factor 4A-I protein 20130415 {GO:0008026=IEA, GO:0000339=TAS, GO:0005515=IPI, GO:0010467=TAS, GO:0016281=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019221=TAS, GO:0004386=TAS, GO:0003743=IEA, GO:0003676=IEA, GO:0003729=TAS, GO:0006412=TAS, GO:0005524=IEA, GO:0006413=TAS, GO:0005829=TAS, GO:0019048=IEA, GO:0044267=TAS, GO:0008135=TAS, GO:0000289=TAS, GO:0000288=TAS} RNA metabolic process, cellular protein metabolic process, cytokine-mediated signaling pathway, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA poly(A) tail shortening, translation, translational initiation, virus-host interaction cytosol, eukaryotic translation initiation factor 4F complex ATP binding, ATP-dependent helicase activity, RNA cap binding, helicase activity, mRNA binding, nucleic acid binding, protein binding, translation factor activity, nucleic acid binding, translation initiation factor activity Human UniProtKB:Q15056 EIF4A2 UniProtKB UniProtKB {GO:0005515=PMID:11408474, GO:0008026=GO_REF:0000002, GO:0010467=Reactome:REACT_71, GO:0016281=PMID:8521730, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019221=Reactome:REACT_25229, GO:0004386=PMID:8521730, GO:0003743=GO_REF:0000038, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000038, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115968, GO:0019048=GO_REF:0000037, GO:0006446=PMID:8521730, GO:0044267=Reactome:REACT_17015, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639} Q9NZE6 BM-010 protein 20130413 {GO:0005515=IPI, GO:0008026=IEA, GO:0010467=TAS, GO:0016281=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019221=TAS, GO:0004386=TAS, GO:0003743=IEA, GO:0003676=IEA, GO:0005524=IEA, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0019048=IEA, GO:0006446=TAS, GO:0044267=TAS, GO:0000289=TAS, GO:0000288=TAS} RNA metabolic process, cellular protein metabolic process, cytokine-mediated signaling pathway, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA poly(A) tail shortening, regulation of translational initiation, translation, translational initiation, virus-host interaction cytosol, eukaryotic translation initiation factor 4F complex ATP binding, ATP-dependent helicase activity, helicase activity, nucleic acid binding, protein binding, translation initiation factor activity Human UniProtKB-KW:KW-0067 EIF4A3 IntAct UniProtKB {GO:0048026=GO_REF:0000019, GO:0005515=PMID:23084401, GO:0017148=PMID:10523622, GO:0010467=Reactome:REACT_71, GO:0006364=GO_REF:0000037, GO:0019221=Reactome:REACT_25229, GO:0005634=GO_REF:0000019, GO:0071013=PMID:11991638, GO:0005829=Reactome:REACT_115968, GO:0004004=PMID:10523622, GO:0005737=PMID:10523622, GO:0000184=Reactome:REACT_75886, GO:0045944=GO_REF:0000019, GO:0008143=PMID:10523622, GO:0035145=PMID:16601204, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639, GO:0008026=GO_REF:0000002, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0045727=PMID:18423201, GO:0003676=GO_REF:0000002, GO:0005524=PMID:10523622, GO:0016607=GO_REF:0000039, GO:0000398=PMID:11991638, GO:0051028=GO_REF:0000037} P38919 Eukaryotic initiation factor 4A-III protein 20130415 {GO:0048026=IEA, GO:0005515=IPI, GO:0017148=IDA, GO:0010467=TAS, GO:0006364=IEA, GO:0019221=TAS, GO:0005634=IEA, GO:0071013=IDA, GO:0005829=TAS, GO:0004004=IDA, GO:0005737=IDA, GO:0000184=TAS, GO:0045944=IEA, GO:0008143=IDA, GO:0035145=IDA, GO:0000289=TAS, GO:0000288=TAS, GO:0008026=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0045727=IMP, GO:0003676=IEA, GO:0005524=IDA, GO:0016607=IEA, GO:0000398=IC, GO:0051028=IEA} RNA metabolic process, cytokine-mediated signaling pathway, gene expression, mRNA metabolic process, mRNA splicing, via spliceosome, mRNA transport, negative regulation of translation, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, nuclear-transcribed mRNA poly(A) tail shortening, positive regulation of mRNA splicing, via spliceosome, positive regulation of transcription from RNA polymerase II promoter, positive regulation of translation, rRNA processing catalytic step 2 spliceosome, cytoplasm, cytosol, exon-exon junction complex, nuclear speck, nucleus ATP binding, ATP-dependent RNA helicase activity, ATP-dependent helicase activity, nucleic acid binding, poly(A) RNA binding, protein binding Human UniProtKB:Q9Y2W1 EIF4B Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0010467=Reactome:REACT_71, GO:0016281=PMID:2390971, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=PMID:2390971, GO:0003743=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_20662, GO:0000166=GO_REF:0000002, GO:0006446=PMID:2390971, GO:0044267=Reactome:REACT_17015, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639} P23588 Eukaryotic translation initiation factor 4B protein 20080912 {GO:0008286=TAS, GO:0010467=TAS, GO:0016281=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=TAS, GO:0003743=IEA, GO:0003676=IEA, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0000166=IEA, GO:0006446=TAS, GO:0044267=TAS, GO:0000289=TAS, GO:0000288=TAS} RNA metabolic process, cellular protein metabolic process, gene expression, insulin receptor signaling pathway, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA poly(A) tail shortening, regulation of translational initiation, translation, translational initiation cytosol, eukaryotic translation initiation factor 4F complex RNA binding, nucleic acid binding, nucleotide binding, translation initiation factor activity Human EIF4E IntAct UniProtKB {GO:0000339=PMID:3469651, GO:0005515=PMID:19060904, GO:0008286=Reactome:REACT_498, GO:0010467=Reactome:REACT_71, GO:0016281=GO_REF:0000019, GO:0010494=PMID:21883093, GO:0030324=GO_REF:0000019, GO:0019221=Reactome:REACT_25229, GO:0003743=GO_REF:0000024, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0016442=PMID:20616046, GO:0005829=Reactome:REACT_115968, GO:0005737=GO_REF:0000002, GO:0000082=PMID:14673156, GO:0006406=Reactome:REACT_1597, GO:0000932=PMID:20616046, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639, GO:0031370=GO_REF:0000019, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006417=GO_REF:0000037, GO:0045931=PMID:14673156, GO:0019048=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0005845=PMID:16271312} P06730 Eukaryotic translation initiation factor 4E protein 20130415 {GO:0000339=TAS, GO:0005515=IPI, GO:0008286=TAS, GO:0010467=TAS, GO:0016281=IEA, GO:0010494=IDA, GO:0030324=IEA, GO:0019221=TAS, GO:0003743=ISS, GO:0006412=TAS, GO:0006413=TAS, GO:0016442=IDA, GO:0005829=TAS, GO:0005737=IEA, GO:0000082=IMP, GO:0006406=TAS, GO:0000932=IDA, GO:0000289=TAS, GO:0000288=TAS, GO:0031370=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0006417=IEA, GO:0045931=IMP, GO:0019048=IEA, GO:0044267=TAS, GO:0005845=IDA} G1/S transition of mitotic cell cycle, RNA metabolic process, cellular protein metabolic process, cytokine-mediated signaling pathway, gene expression, insulin receptor signaling pathway, lung development, mRNA export from nucleus, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA poly(A) tail shortening, positive regulation of mitotic cell cycle, regulation of translation, translation, translational initiation, virus-host interaction RNA-induced silencing complex, cytoplasm, cytoplasmic mRNA processing body, cytoplasmic stress granule, cytosol, eukaryotic translation initiation factor 4F complex, mRNA cap binding complex RNA cap binding, eukaryotic initiation factor 4G binding, protein binding, translation initiation factor activity Human UniProtKB:Q9NRA8 EIF4E2 IntAct UniProtKB {GO:0017148=PMID:22751931, GO:0000339=PMID:9582349, GO:0005515=PMID:19060904, GO:0005737=GO_REF:0000002, GO:0019221=Reactome:REACT_25229, GO:0003743=GO_REF:0000037, GO:0008135=PMID:9582349, GO:0031625=PMID:14623119, GO:0005845=PMID:17368478, GO:0005829=Reactome:REACT_115968} O60573 Eukaryotic translation initiation factor 4E type 2 protein 20130415 {GO:0017148=IMP, GO:0000339=TAS, GO:0005515=IPI, GO:0005737=IEA, GO:0019221=TAS, GO:0003743=IEA, GO:0008135=TAS, GO:0031625=IPI, GO:0005845=IDA, GO:0005829=TAS} cytokine-mediated signaling pathway, negative regulation of translation cytoplasm, cytosol, mRNA cap binding complex RNA cap binding, protein binding, translation factor activity, nucleic acid binding, translation initiation factor activity, ubiquitin protein ligase binding Human UniProtKB:Q9NRA8 EIF4E3 Reactome UniProtKB {GO:0005737=GO_REF:0000002, GO:0019221=Reactome:REACT_25229, GO:0003743=GO_REF:0000037, GO:0005845=GO_REF:0000024, GO:0006417=GO_REF:0000037, GO:0005829=Reactome:REACT_115968} Q8N5X7 Eukaryotic translation initiation factor 4E type 3 protein 20130301 {GO:0005737=IEA, GO:0019221=TAS, GO:0003743=IEA, GO:0005845=ISS, GO:0006417=IEA, GO:0005829=TAS} cytokine-mediated signaling pathway, regulation of translation cytoplasm, cytosol, mRNA cap binding complex translation initiation factor activity Human EIF4EBP1 HPA UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005515=PMID:16189514, GO:0031929=PMID:12150926, GO:0010467=Reactome:REACT_71, GO:0030324=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_6873, GO:0043234=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0045931=PMID:14673156, GO:0000082=PMID:14673156, GO:0031333=GO_REF:0000019, GO:0008190=GO_REF:0000019, GO:0045947=GO_REF:0000019, GO:0044267=Reactome:REACT_17015} Q13541 Eukaryotic translation initiation factor 4E-binding protein 1 protein 20101115 {GO:0008286=TAS, GO:0005515=IPI, GO:0031929=IDA, GO:0010467=TAS, GO:0030324=IEA, GO:0045471=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0043234=IEA, GO:0005737=IDA, GO:0045931=IMP, GO:0000082=IMP, GO:0031333=IEA, GO:0008190=IEA, GO:0045947=IEA, GO:0044267=TAS} G1/S transition of mitotic cell cycle, TOR signaling cascade, cellular protein metabolic process, gene expression, insulin receptor signaling pathway, lung development, negative regulation of protein complex assembly, negative regulation of translational initiation, positive regulation of mitotic cell cycle, response to ethanol, translation, translational initiation cytoplasm, cytosol, nucleolus, nucleus, protein complex eukaryotic initiation factor 4E binding, protein binding Human EIF4EBP2 PINC UniProtKB {GO:0005515=PMID:16271312, GO:0008286=GO_REF:0000019, GO:0019933=GO_REF:0000019, GO:0008190=GO_REF:0000002, GO:0045947=GO_REF:0000002, GO:0006412=PMID:7935836} Q13542 Eukaryotic translation initiation factor 4E-binding protein 2 protein 20030904 {GO:0005515=IPI, GO:0008286=IEA, GO:0019933=IEA, GO:0008190=IEA, GO:0045947=IEA, GO:0006412=TAS} cAMP-mediated signaling, insulin receptor signaling pathway, negative regulation of translational initiation, translation eukaryotic initiation factor 4E binding, protein binding Human EIF4EBP3 IntAct UniProtKB {GO:0005515=PMID:15153109, GO:0016281=PMID:9593750, GO:0008190=GO_REF:0000002, GO:0045947=PMID:9593750, GO:0030371=PMID:9593750} O60516 Eukaryotic translation initiation factor 4E-binding protein 3 protein 20130415 {GO:0005515=IPI, GO:0016281=NAS, GO:0008190=IEA, GO:0045947=NAS, GO:0030371=NAS} negative regulation of translational initiation eukaryotic translation initiation factor 4F complex eukaryotic initiation factor 4E binding, protein binding, translation repressor activity Human UniProtKB:Q80ZJ3 EIF4ENIF1 HPA UniProtKB {GO:0005515=PMID:19060904, GO:0005737=PMID:10856257, GO:0016607=GO_REF:0000039, GO:0016605=GO_REF:0000039, GO:0008565=PMID:10856257, GO:0003743=GO_REF:0000038, GO:0005634=PMID:10856257, GO:0005829=GO_REF:0000019, GO:0043231=GO_REF:0000052} Q9NRA8 Eukaryotic translation initiation factor 4E transporter protein 20101115 {GO:0005515=IPI, GO:0005737=TAS, GO:0016607=IEA, GO:0016605=IEA, GO:0008565=TAS, GO:0003743=IEA, GO:0005634=TAS, GO:0005829=IEA, GO:0043231=IDA} PML body, cytoplasm, cytosol, intracellular membrane-bounded organelle, nuclear speck, nucleus protein binding, protein transporter activity, translation initiation factor activity Human EIF4G1 IntAct UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005515=PMID:19716330, GO:0010467=Reactome:REACT_71, GO:0008219=GO_REF:0000037, GO:0016281=PMID:9857202, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=GO_REF:0000002, GO:0019221=Reactome:REACT_25229, GO:0003743=PMID:9372926, GO:0006412=Reactome:REACT_1014, GO:0003677=GO_REF:0000002, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115968, GO:0005737=GO_REF:0000029, GO:0000184=Reactome:REACT_75886, GO:0019048=GO_REF:0000037, GO:0006446=PMID:9372926, GO:0044267=Reactome:REACT_17015, GO:0000289=Reactome:REACT_20514, GO:0008135=PMID:9857202, GO:0000288=Reactome:REACT_20639} Q04637 Eukaryotic translation initiation factor 4 gamma 1 protein 20130415 {GO:0008286=TAS, GO:0005515=IPI, GO:0010467=TAS, GO:0008219=IEA, GO:0016281=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=IEA, GO:0019221=TAS, GO:0003743=TAS, GO:0006412=TAS, GO:0003677=IEA, GO:0006413=TAS, GO:0005829=TAS, GO:0005737=NAS, GO:0000184=TAS, GO:0019048=IEA, GO:0006446=NAS, GO:0044267=TAS, GO:0000289=TAS, GO:0008135=TAS, GO:0000288=TAS} RNA metabolic process, cell death, cellular protein metabolic process, cytokine-mediated signaling pathway, gene expression, insulin receptor signaling pathway, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, nuclear-transcribed mRNA poly(A) tail shortening, regulation of translational initiation, translation, translational initiation, virus-host interaction cytoplasm, cytosol, eukaryotic translation initiation factor 4F complex DNA binding, RNA binding, protein binding, translation factor activity, nucleic acid binding, translation initiation factor activity Human UniProtKB:P11940 EIF4G2 IntAct UniProtKB {GO:0005515=PMID:16166382, GO:0008219=PMID:9032289, GO:0016281=PMID:11943866, GO:0016070=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0019221=Reactome:REACT_25229, GO:0003743=PMID:11943866, GO:0003677=GO_REF:0000002, GO:0005829=Reactome:REACT_115968, GO:0005737=GO_REF:0000019, GO:0006446=PMID:11943866, GO:0007050=PMID:9032289, GO:0008135=PMID:16289705} P78344 Eukaryotic translation initiation factor 4 gamma 2 protein 20130415 {GO:0005515=IPI, GO:0008219=TAS, GO:0016281=IDA, GO:0016070=IEA, GO:0003723=IEA, GO:0019221=TAS, GO:0003743=IDA, GO:0003677=IEA, GO:0005829=TAS, GO:0005737=IEA, GO:0006446=IDA, GO:0007050=TAS, GO:0008135=IDA} RNA metabolic process, cell cycle arrest, cell death, cytokine-mediated signaling pathway, regulation of translational initiation cytoplasm, cytosol, eukaryotic translation initiation factor 4F complex DNA binding, RNA binding, protein binding, translation factor activity, nucleic acid binding, translation initiation factor activity Human UniProtKB:P60842 EIF4G3 InterPro UniProtKB {GO:0000339=PMID:9418880, GO:0016281=PMID:9418880, GO:0016070=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0019221=Reactome:REACT_25229, GO:0003743=GO_REF:0000037, GO:0045727=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0003677=GO_REF:0000002, GO:0005829=Reactome:REACT_115968, GO:0007128=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0006446=PMID:9418880, GO:0001934=GO_REF:0000019, GO:0008135=PMID:9418880} Q5SWD0 Eukaryotic translation initiation factor 4 gamma 3 protein 20130413 {GO:0000339=TAS, GO:0016281=TAS, GO:0016070=IEA, GO:0003723=IEA, GO:0019221=TAS, GO:0003743=IEA, GO:0045727=IEA, GO:0007283=IEA, GO:0003677=IEA, GO:0005829=TAS, GO:0007128=IEA, GO:0019048=IEA, GO:0006446=TAS, GO:0001934=IEA, GO:0008135=TAS} RNA metabolic process, cytokine-mediated signaling pathway, meiotic prophase I, positive regulation of protein phosphorylation, positive regulation of translation, regulation of translational initiation, spermatogenesis, virus-host interaction cytosol, eukaryotic translation initiation factor 4F complex DNA binding, RNA binding, RNA cap binding, translation factor activity, nucleic acid binding, translation initiation factor activity Human InterPro:IPR016021 EIF4H IntAct UniProtKB {GO:0005515=PMID:19203580, GO:0010467=Reactome:REACT_71, GO:0048471=GO_REF:0000039, GO:0016281=PMID:9516461, GO:0003723=PMID:8812460, GO:0003743=GO_REF:0000037, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1904, GO:0019953=GO_REF:0000019, GO:0048589=GO_REF:0000019, GO:0000166=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0006446=PMID:9516461, GO:0044267=Reactome:REACT_17015, GO:0008135=PMID:9516461} Q15056 Eukaryotic translation initiation factor 4H protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0048471=IEA, GO:0016281=TAS, GO:0003723=TAS, GO:0003743=IEA, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0019953=IEA, GO:0048589=IEA, GO:0000166=IEA, GO:0019048=IEA, GO:0006446=TAS, GO:0044267=TAS, GO:0008135=TAS} cellular protein metabolic process, developmental growth, gene expression, regulation of translational initiation, sexual reproduction, translation, translational initiation, virus-host interaction cytosol, eukaryotic translation initiation factor 4F complex, perinuclear region of cytoplasm RNA binding, nucleotide binding, protein binding, translation factor activity, nucleic acid binding, translation initiation factor activity Human UniProtKB:P60842 EIF5 GOC UniProtKB {GO:0010467=Reactome:REACT_71, GO:0016070=GO_REF:0000002, GO:0003924=PMID:8663286, GO:0003743=PMID:8663286, GO:0005525=GO_REF:0000037, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_1060, GO:0006184=PMID:8663286, GO:0005737=GO_REF:0000052, GO:0006446=PMID:8663286, GO:0044267=Reactome:REACT_17015, GO:0008135=PMID:8663286} P55010 Eukaryotic translation initiation factor 5 protein 20130413 {GO:0010467=TAS, GO:0016070=IEA, GO:0003924=TAS, GO:0003743=NAS, GO:0005525=IEA, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006184=TAS, GO:0005737=IDA, GO:0006446=TAS, GO:0044267=TAS, GO:0008135=TAS} GTP catabolic process, RNA metabolic process, cellular protein metabolic process, gene expression, regulation of translational initiation, translation, translational initiation cytoplasm, cytosol GTP binding, GTPase activity, translation factor activity, nucleic acid binding, translation initiation factor activity Human EIF5A Reactome UniProtKB {GO:0005515=PMID:17213197, GO:0008284=PMID:14622290, GO:0008612=Reactome:REACT_12469, GO:0003723=PMID:15303967, GO:0005634=PMID:17187778, GO:0006917=PMID:15371445, GO:0003746=GO_REF:0000024, GO:0005829=Reactome:REACT_12551, GO:0006913=PMID:10381392, GO:0006452=GO_REF:0000002, GO:0045905=GO_REF:0000002, GO:0005737=PMID:12210765, GO:0047485=PMID:15371445, GO:0006406=PMID:9465063, GO:0005643=PMID:10381392, GO:0005642=PMID:12210765, GO:0006611=PMID:8596953, GO:0005789=GO_REF:0000039, GO:0043022=GO_REF:0000002, GO:0017070=PMID:9285100, GO:0044267=Reactome:REACT_17015, GO:0045901=GO_REF:0000024, GO:0043687=Reactome:REACT_22161} P63241 Eukaryotic translation initiation factor 5A-1 protein 20130301 {GO:0005515=IPI, GO:0008284=IGI, GO:0008612=TAS, GO:0003723=IDA, GO:0005634=IDA, GO:0006917=IDA, GO:0003746=ISS, GO:0005829=TAS, GO:0006913=IMP, GO:0006452=IEA, GO:0045905=IEA, GO:0005737=IDA, GO:0047485=IPI, GO:0006406=IMP, GO:0005643=IDA, GO:0005642=IDA, GO:0006611=IMP, GO:0005789=IEA, GO:0043022=IEA, GO:0017070=IDA, GO:0044267=TAS, GO:0045901=ISS, GO:0043687=TAS} cellular protein metabolic process, induction of apoptosis, mRNA export from nucleus, nucleocytoplasmic transport, peptidyl-lysine modification to hypusine, positive regulation of cell proliferation, positive regulation of translational elongation, positive regulation of translational termination, post-translational protein modification, protein export from nucleus, translational frameshifting annulate lamellae, cytoplasm, cytosol, endoplasmic reticulum membrane, nuclear pore, nucleus RNA binding, U6 snRNA binding, protein N-terminus binding, protein binding, ribosome binding, translation elongation factor activity Human EIF5A2 Reactome UniProtKB {GO:0005515=PMID:14622290, GO:0008284=PMID:14622290, GO:0008612=Reactome:REACT_12469, GO:0007283=PMID:11161802, GO:0003746=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0005829=Reactome:REACT_12551, GO:0006452=GO_REF:0000002, GO:0045905=GO_REF:0000002, GO:0005643=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0043022=GO_REF:0000002, GO:0051028=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0045901=GO_REF:0000002, GO:0010509=PMID:11161802, GO:0043687=Reactome:REACT_22161} Q9GZV4 Eukaryotic translation initiation factor 5A-2 protein 20130301 {GO:0005515=IPI, GO:0008284=IGI, GO:0008612=TAS, GO:0007283=NAS, GO:0003746=IEA, GO:0015031=IEA, GO:0005829=TAS, GO:0006452=IEA, GO:0045905=IEA, GO:0005643=IEA, GO:0005789=IEA, GO:0043022=IEA, GO:0051028=IEA, GO:0044267=TAS, GO:0045901=IEA, GO:0010509=NAS, GO:0043687=TAS} cellular protein metabolic process, mRNA transport, peptidyl-lysine modification to hypusine, polyamine homeostasis, positive regulation of cell proliferation, positive regulation of translational elongation, positive regulation of translational termination, post-translational protein modification, protein transport, spermatogenesis, translational frameshifting cytosol, endoplasmic reticulum membrane, nuclear pore protein binding, ribosome binding, translation elongation factor activity Human EIF5AL1 UniProtKB UniProtKB {GO:0045905=GO_REF:0000002, GO:0006452=GO_REF:0000002, GO:0008612=GO_REF:0000002, GO:0005643=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0043022=GO_REF:0000002, GO:0051028=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0003746=GO_REF:0000037, GO:0045901=GO_REF:0000002} Q6IS14 Eukaryotic translation initiation factor 5A-1-like protein 20130413 {GO:0045905=IEA, GO:0006452=IEA, GO:0008612=IEA, GO:0005643=IEA, GO:0005789=IEA, GO:0043022=IEA, GO:0051028=IEA, GO:0015031=IEA, GO:0003746=IEA, GO:0045901=IEA} mRNA transport, peptidyl-lysine modification to hypusine, positive regulation of translational elongation, positive regulation of translational termination, protein transport, translational frameshifting endoplasmic reticulum membrane, nuclear pore ribosome binding, translation elongation factor activity Human UniProtKB-SubCell:SL-0097 EIF5B IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0010467=Reactome:REACT_71, GO:0006446=PMID:10200264, GO:0003924=GO_REF:0000002, GO:0003743=PMID:10200264, GO:0005525=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_198} O60841 Eukaryotic translation initiation factor 5B protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0006446=NAS, GO:0003924=IEA, GO:0003743=NAS, GO:0005525=IEA, GO:0044267=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS} cellular protein metabolic process, gene expression, regulation of translational initiation, translation, translational initiation cytosol GTP binding, GTPase activity, protein binding, translation initiation factor activity Human UniProtKB:P14921 EIF6 HPA UniProtKB {GO:0005515=PMID:21903422, GO:0005737=GO_REF:0000039, GO:0042256=PMID:21536732, GO:0005730=GO_REF:0000052, GO:0003743=GO_REF:0000020, GO:0043022=PMID:21536732, GO:0005634=GO_REF:0000052, GO:0043023=GO_REF:0000020, GO:0042273=GO_REF:0000020, GO:0000054=GO_REF:0000020, GO:0005638=GO_REF:0000019} P56537 Eukaryotic translation initiation factor 6 protein 20111111 {GO:0005515=IPI, GO:0005737=IEA, GO:0042256=IMP, GO:0005730=IDA, GO:0003743=IEA, GO:0043022=IDA, GO:0005634=IDA, GO:0043023=IEA, GO:0042273=IEA, GO:0000054=IEA, GO:0005638=IEA} mature ribosome assembly, ribosomal large subunit biogenesis, ribosomal subunit export from nucleus cytoplasm, lamin filament, nucleolus, nucleus protein binding, ribosomal large subunit binding, ribosome binding, translation initiation factor activity NOT Human ELAC2 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0004519=GO_REF:0000037, GO:0016787=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0046872=GO_REF:0000037, GO:0008033=GO_REF:0000037} Q9BQ52 Zinc phosphodiesterase ELAC protein 2 protein 20130413 {GO:0005739=IEA, GO:0004519=IEA, GO:0016787=IEA, GO:0005634=IEA, GO:0046872=IEA, GO:0008033=IEA} tRNA processing mitochondrion, nucleus endonuclease activity, hydrolase activity, metal ion binding Human UniProtKB-SubCell:SL-0191 ELANE BHF-UCL UniProtKB {GO:0005515=PMID:21979170, GO:0004252=GO_REF:0000002, GO:0002020=PMID:6980881, GO:0030163=PMID:12887060, GO:0050922=PMID:15140022, GO:0022617=Reactome:REACT_118572, GO:0043406=PMID:14730209, GO:0030198=Reactome:REACT_118779, GO:0045079=PMID:12223522, GO:0030574=Reactome:REACT_150401, GO:0006508=PMID:11907569, GO:0030141=PMID:11907569, GO:0009411=PMID:11928814, GO:0008201=PMID:11907569, GO:0009986=PMID:12114510, GO:0045415=PMID:12223522, GO:0045416=PMID:14730209, GO:0006874=PMID:15140022, GO:0005576=Reactome:REACT_150438, GO:0048661=PMID:15010259, GO:0051635=PMID:14705961, GO:0019955=PMID:12393522, GO:0004175=PMID:6980881, GO:0050728=PMID:15140022, GO:0008233=PMID:11907569} P08246 Neutrophil elastase protein 20111202 {GO:0005515=IPI, GO:0004252=IEA, GO:0002020=IPI, GO:0030163=NAS, GO:0050922=NAS, GO:0022617=TAS, GO:0043406=NAS, GO:0030198=TAS, GO:0045079=IDA, GO:0030574=TAS, GO:0006508=IDA, GO:0030141=IDA, GO:0009411=IDA, GO:0008201=IDA, GO:0009986=IDA, GO:0045415=IDA, GO:0045416=IDA, GO:0006874=NAS, GO:0005576=TAS, GO:0048661=IDA, GO:0051635=NAS, GO:0019955=IPI, GO:0004175=IDA, GO:0050728=NAS, GO:0008233=IDA} cellular calcium ion homeostasis, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, negative regulation of chemokine biosynthetic process, negative regulation of chemotaxis, negative regulation of inflammatory response, negative regulation of interleukin-8 biosynthetic process, positive regulation of MAP kinase activity, positive regulation of interleukin-8 biosynthetic process, positive regulation of smooth muscle cell proliferation, protein catabolic process, proteolysis, response to UV cell surface, extracellular region, secretory granule bacterial cell surface binding, cytokine binding, endopeptidase activity, heparin binding, peptidase activity, protease binding, protein binding, serine-type endopeptidase activity Human ELAVL1 Reactome UniProtKB {GO:0005515=PMID:17932509, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0019901=PMID:14517288, GO:0016071=Reactome:REACT_20605, GO:0003723=PMID:21613615, GO:0005634=PMID:14517288, GO:0007275=PMID:9003489, GO:0045727=PMID:21613615, GO:0003729=PMID:10660597, GO:0035925=PMID:23056314, GO:0006417=PMID:23056314, GO:0005829=Reactome:REACT_24924, GO:0005737=PMID:14517288, GO:0000166=GO_REF:0000002, GO:0017091=PMID:14517288, GO:0005654=Reactome:REACT_25286, GO:0048255=PMID:21613615, GO:0070935=PMID:14517288} Q15717 ELAV-like protein 1 protein 20091216 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0019901=IPI, GO:0016071=TAS, GO:0003723=IDA, GO:0005634=IDA, GO:0007275=TAS, GO:0045727=IDA, GO:0003729=TAS, GO:0035925=IDA, GO:0006417=IMP, GO:0005829=TAS, GO:0005737=IDA, GO:0000166=IEA, GO:0017091=IDA, GO:0005654=TAS, GO:0048255=IDA, GO:0070935=IDA} 3'-UTR-mediated mRNA stabilization, RNA metabolic process, gene expression, mRNA metabolic process, mRNA stabilization, multicellular organismal development, positive regulation of translation, regulation of translation cytoplasm, cytosol, nucleoplasm, nucleus AU-rich element binding, RNA binding, mRNA 3'-UTR AU-rich region binding, mRNA binding, nucleotide binding, protein binding, protein kinase binding Human ELAVL2 PINC UniProtKB {GO:0005515=PMID:17289661, GO:0006355=PMID:8158249, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000038, GO:0003730=PMID:8158249} Q12926 ELAV-like protein 2 protein 20030904 {GO:0005515=IPI, GO:0006355=TAS, GO:0000166=IEA, GO:0003723=IEA, GO:0003730=TAS} regulation of transcription, DNA-dependent RNA binding, mRNA 3'-UTR binding, nucleotide binding, protein binding Human ELAVL3 UniProtKB UniProtKB {GO:0000166=GO_REF:0000002, GO:0017091=PMID:10710437, GO:0003676=GO_REF:0000002, GO:0030154=GO_REF:0000037, GO:0007399=GO_REF:0000037} Q14576 ELAV-like protein 3 protein 20090731 {GO:0000166=IEA, GO:0017091=IDA, GO:0003676=IEA, GO:0030154=IEA, GO:0007399=IEA} cell differentiation, nervous system development AU-rich element binding, nucleic acid binding, nucleotide binding Human ELAVL4 PINC UniProtKB {GO:0006397=PMID:10348344, GO:0006396=PMID:1655278, GO:0000166=GO_REF:0000002, GO:0003723=PMID:1655278, GO:0017091=PMID:10710437, GO:0003730=PMID:10848602} P26378 ELAV-like protein 4 protein 20030904 {GO:0006397=TAS, GO:0006396=TAS, GO:0000166=IEA, GO:0003723=TAS, GO:0017091=IDA, GO:0003730=TAS} RNA processing, mRNA processing AU-rich element binding, RNA binding, mRNA 3'-UTR binding, nucleotide binding Human ELF1 ENSEMBL UniProtKB {GO:0005515=PMID:18692240, GO:0043565=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0003700=PMID:14970218, GO:0045944=PMID:19674970, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000019, GO:0045893=PMID:19674970, GO:0001817=GO_REF:0000019, GO:0050860=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q5T9E7 ETS-related transcription factor Elf-1 protein 20130413 {GO:0005515=IPI, GO:0043565=IEA, GO:0005737=IDA, GO:0003700=IDA, GO:0045944=IDA, GO:0005730=IDA, GO:0005634=IEA, GO:0045893=IDA, GO:0001817=IEA, GO:0050860=IEA, GO:0006351=IEA} negative regulation of T cell receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of cytokine production, transcription, DNA-dependent cytoplasm, nucleolus, nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human Ensembl:ENSMUSP00000046515 ELF2 HPA UniProtKB {GO:0005515=PMID:14970218, GO:0043565=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0003700=GO_REF:0000002, GO:0006357=PMID:8756667, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0045893=PMID:8756667, GO:0006351=GO_REF:0000037} Q15723 ETS-related transcription factor Elf-2 protein 20101115 {GO:0005515=IPI, GO:0043565=IEA, GO:0005737=IDA, GO:0003700=IEA, GO:0006357=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0045893=IDA, GO:0006351=IEA} positive regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, nucleolus, nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human ELF3 HPA UniProtKB {GO:0005515=PMID:15075319, GO:0005794=GO_REF:0000052, GO:0003700=PMID:9234700, GO:0006366=PMID:9234700, GO:0060056=GO_REF:0000024, GO:0001824=GO_REF:0000019, GO:0003713=PMID:12624109, GO:0005730=GO_REF:0000052, GO:0007275=PMID:9234700, GO:0005634=GO_REF:0000052, GO:0043565=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0006954=PMID:14715662, GO:0008544=PMID:9234700, GO:0030198=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0030855=PMID:9234700, GO:0045893=PMID:9234700, GO:0045892=PMID:10773884} Q5SR36 ETS-related transcription factor Elf-3 protein 20101115 {GO:0005515=IPI, GO:0005794=IDA, GO:0003700=NAS, GO:0006366=TAS, GO:0060056=ISS, GO:0001824=IEA, GO:0003713=IDA, GO:0005730=IDA, GO:0007275=TAS, GO:0005634=IDA, GO:0043565=IEA, GO:0005737=IDA, GO:0006954=IEP, GO:0008544=NAS, GO:0030198=IEA, GO:0045944=IEA, GO:0030855=IEP, GO:0045893=IDA, GO:0045892=IDA} blastocyst development, epidermis development, epithelial cell differentiation, extracellular matrix organization, inflammatory response, mammary gland involution, multicellular organismal development, negative regulation of transcription, DNA-dependent, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter Golgi apparatus, cytoplasm, nucleolus, nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity Human ELF4 UniProtKB UniProtKB {GO:0005515=PMID:14970218, GO:0043565=GO_REF:0000002, GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000029, GO:0016605=PMID:14970218, GO:0045944=PMID:14625302, GO:0001787=GO_REF:0000024, GO:0005634=GO_REF:0000029, GO:0045893=PMID:14625302, GO:0001866=GO_REF:0000024, GO:0006351=GO_REF:0000037} Q99607 ETS-related transcription factor Elf-4 protein 20060711 {GO:0005515=IPI, GO:0043565=IEA, GO:0006355=NAS, GO:0003700=NAS, GO:0016605=IDA, GO:0045944=IDA, GO:0001787=ISS, GO:0005634=NAS, GO:0045893=IDA, GO:0001866=ISS, GO:0006351=IEA} NK T cell proliferation, natural killer cell proliferation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent PML body, nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:Q01196-1 ELF5 PINC UniProtKB {GO:0043565=GO_REF:0000002, GO:0005737=GO_REF:0000019, GO:0060644=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0006366=PMID:9840936, GO:0008283=PMID:9840936, GO:0005634=GO_REF:0000039, GO:0007398=GO_REF:0000019} Q9UKW6 ETS-related transcription factor Elf-5 protein 20061106 {GO:0043565=IEA, GO:0005737=IEA, GO:0060644=IEA, GO:0003700=IEA, GO:0006366=TAS, GO:0008283=TAS, GO:0005634=IEA, GO:0007398=IEA} cell proliferation, ectoderm development, mammary gland epithelial cell differentiation, transcription from RNA polymerase II promoter cytoplasm, nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human ELFN1 UniProtKB UniProtKB {GO:0050808=GO_REF:0000024, GO:0019902=PMID:19389623, GO:0010923=PMID:19389623, GO:0004864=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0060076=GO_REF:0000024, GO:0030425=GO_REF:0000024} P0C7U0 Protein ELFN1 protein 20121101 {GO:0050808=ISS, GO:0019902=IDA, GO:0010923=IDA, GO:0004864=IEA, GO:0016021=IEA, GO:0060076=ISS, GO:0030425=ISS} negative regulation of phosphatase activity, synapse organization dendrite, excitatory synapse, integral to membrane phosphatase binding, protein phosphatase inhibitor activity Human UniProtKB:Q8C8T7 ELFN2 UniProtKB UniProtKB {GO:0019902=PMID:19389623, GO:0010923=PMID:19389623, GO:0004864=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q5R3F8 Protein phosphatase 1 regulatory subunit 29 protein 20111103 {GO:0019902=IDA, GO:0010923=IDA, GO:0004864=IEA, GO:0016021=IEA} negative regulation of phosphatase activity integral to membrane phosphatase binding, protein phosphatase inhibitor activity Human ELK1 BHF-UCL UniProtKB {GO:0005515=PMID:17296730, GO:0048011=Reactome:REACT_11061, GO:0038124=Reactome:REACT_8006, GO:0003700=PMID:14970218, GO:0034142=Reactome:REACT_6894, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0005634=PMID:20018936, GO:0002224=Reactome:REACT_9020, GO:0051403=Reactome:REACT_21308, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0002756=Reactome:REACT_6782, GO:0002755=Reactome:REACT_27215, GO:0045087=Reactome:REACT_6802, GO:0045944=PMID:22065586, GO:0035666=Reactome:REACT_25281, GO:0034166=Reactome:REACT_9027, GO:0045893=PMID:15790681, GO:0034146=Reactome:REACT_9061, GO:0034138=Reactome:REACT_6783, GO:0034162=Reactome:REACT_9047} P19419 ETS domain-containing protein Elk-1 protein 20110427 {GO:0005515=IPI, GO:0048011=TAS, GO:0038124=TAS, GO:0003700=IDA, GO:0034142=TAS, GO:0038123=TAS, GO:0034134=TAS, GO:0005634=IDA, GO:0002224=TAS, GO:0051403=TAS, GO:0006351=IEA, GO:0043565=IEA, GO:0002756=TAS, GO:0002755=TAS, GO:0045087=TAS, GO:0045944=IMP, GO:0035666=TAS, GO:0034166=TAS, GO:0045893=IDA, GO:0034146=TAS, GO:0034138=TAS, GO:0034162=TAS} MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, innate immune response, neurotrophin TRK receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, transcription, DNA-dependent nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human ELK3 HPA UniProtKB {GO:0005515=PMID:17474147, GO:0003700=GO_REF:0000019, GO:0003714=PMID:12933792, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0001525=GO_REF:0000019, GO:0032422=PMID:12933792, GO:0006351=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0043565=GO_REF:0000002, GO:0005739=GO_REF:0000052, GO:0007165=PMID:7958835, GO:0042060=GO_REF:0000019, GO:0045892=PMID:12933792} P41970 ETS domain-containing protein Elk-3 protein 20080818 {GO:0005515=IPI, GO:0003700=IEA, GO:0003714=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0001525=IEA, GO:0032422=IDA, GO:0006351=IEA, GO:0043231=IDA, GO:0043565=IEA, GO:0005739=IDA, GO:0007165=TAS, GO:0042060=IEA, GO:0045892=IDA} angiogenesis, negative regulation of transcription, DNA-dependent, signal transduction, transcription, DNA-dependent, wound healing intracellular membrane-bounded organelle, mitochondrion, nucleolus, nucleus protein binding, purine-rich negative regulatory element binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human ELK4 HPA UniProtKB {GO:0005515=PMID:22722849, GO:0003712=PMID:7851904, GO:0070932=PMID:22722849, GO:0003700=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0001047=PMID:22722849, GO:0005634=GO_REF:0000052, GO:0000122=PMID:22722849, GO:0003677=PMID:1339307, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0003682=PMID:22722849} P28324 ETS domain-containing protein Elk-4 protein 20101115 {GO:0005515=IPI, GO:0003712=TAS, GO:0070932=IDA, GO:0003700=IEA, GO:0005730=IDA, GO:0001047=TAS, GO:0005634=IDA, GO:0000122=IMP, GO:0003677=TAS, GO:0006351=IEA, GO:0043565=IEA, GO:0005737=IDA, GO:0003682=IDA} histone H3 deacetylation, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, nucleolus, nucleus DNA binding, chromatin binding, core promoter binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription cofactor activity Human ELL IntAct UniProtKB {GO:0005515=PMID:19389623, GO:0010467=Reactome:REACT_71, GO:0022415=Reactome:REACT_6361, GO:0006368=Reactome:REACT_1845, GO:0015030=GO_REF:0000039, GO:0006366=Reactome:REACT_1366, GO:0019902=PMID:19389623, GO:0008023=GO_REF:0000002, GO:0001701=GO_REF:0000019, GO:0050434=Reactome:REACT_6162, GO:0032786=PMID:8596958, GO:0016607=PMID:19389623, GO:0010923=PMID:19389623, GO:0016032=Reactome:REACT_6256, GO:0005654=Reactome:REACT_6355} P55199 RNA polymerase II elongation factor ELL protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0022415=TAS, GO:0006368=TAS, GO:0015030=IEA, GO:0006366=TAS, GO:0019902=IDA, GO:0008023=IEA, GO:0001701=IEA, GO:0050434=TAS, GO:0032786=TAS, GO:0016607=IDA, GO:0010923=IDA, GO:0016032=TAS, GO:0005654=TAS} gene expression, in utero embryonic development, negative regulation of phosphatase activity, positive regulation of DNA-dependent transcription, elongation, positive regulation of viral transcription, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, viral reproduction, viral reproductive process Cajal body, nuclear speck, nucleoplasm, transcription elongation factor complex phosphatase binding, protein binding Human UniProtKB:P62136 ELL2 HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0006368=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003746=GO_REF:0000038, GO:0008023=GO_REF:0000002} O00472 RNA polymerase II elongation factor ELL2 protein 20110516 {GO:0006355=IEA, GO:0006368=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003746=IEA, GO:0008023=IEA} regulation of transcription, DNA-dependent, transcription elongation from RNA polymerase II promoter nucleolus, nucleus, transcription elongation factor complex translation elongation factor activity NOT Human ELL3 HPA UniProtKB {GO:0048863=GO_REF:0000024, GO:0006368=PMID:10882741, GO:0032786=PMID:10882741, GO:0006354=PMID:10882741, GO:0006366=GO_REF:0000024, GO:0045944=PMID:10882741, GO:0005730=GO_REF:0000052, GO:0010717=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0007283=PMID:10882741, GO:0008023=PMID:10882741, GO:0035326=GO_REF:0000024} Q9HB65 RNA polymerase II elongation factor ELL3 protein 20110516 {GO:0048863=ISS, GO:0006368=IDA, GO:0032786=IDA, GO:0006354=IDA, GO:0006366=ISS, GO:0045944=IDA, GO:0005730=IDA, GO:0010717=ISS, GO:0005634=IDA, GO:0007283=NAS, GO:0008023=NAS, GO:0035326=ISS} DNA-dependent transcription, elongation, positive regulation of DNA-dependent transcription, elongation, positive regulation of transcription from RNA polymerase II promoter, regulation of epithelial to mesenchymal transition, spermatogenesis, stem cell differentiation, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter nucleolus, nucleus, transcription elongation factor complex enhancer binding NOT Human ELMO1 IntAct UniProtKB {GO:0005515=PMID:15247908, GO:0006909=GO_REF:0000002, GO:0030029=GO_REF:0000019, GO:0017124=PMID:12029088, GO:0030036=PMID:11595183, GO:0005886=PMID:11595183, GO:0006928=PMID:11595183, GO:0006915=PMID:11595183, GO:0006911=PMID:11595183, GO:0050690=Reactome:REACT_11068, GO:0005829=Reactome:REACT_160134, GO:0016601=PMID:11595183, GO:0005737=GO_REF:0000054, GO:0005543=GO_REF:0000002, GO:0045087=Reactome:REACT_6802, GO:0016032=Reactome:REACT_6185, GO:0005856=GO_REF:0000002, GO:0038096=Reactome:REACT_160123} Q92556 Engulfment and cell motility protein 1 protein 20130415 {GO:0005515=IPI, GO:0006909=IEA, GO:0030029=IEA, GO:0017124=IPI, GO:0030036=IGI, GO:0005886=IDA, GO:0006928=IGI, GO:0006915=NAS, GO:0006911=IGI, GO:0050690=TAS, GO:0005829=TAS, GO:0016601=IGI, GO:0005737=IDA, GO:0005543=IEA, GO:0045087=TAS, GO:0016032=TAS, GO:0005856=IEA, GO:0038096=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, Rac protein signal transduction, actin cytoskeleton organization, actin filament-based process, apoptotic process, cellular component movement, innate immune response, phagocytosis, phagocytosis, engulfment, regulation of defense response to virus by virus, viral reproduction cytoplasm, cytoskeleton, cytosol, plasma membrane SH3 domain binding, phospholipid binding, protein binding Human UniProtKB:Q14185 ELMO2 Reactome UniProtKB {GO:0005515=PMID:20679435, GO:0006909=GO_REF:0000002, GO:0030971=PMID:20679435, GO:0017124=GO_REF:0000037, GO:0005543=GO_REF:0000002, GO:0016020=PMID:20679435, GO:0060326=PMID:20679435, GO:0045087=Reactome:REACT_6802, GO:0006915=GO_REF:0000037, GO:0005856=GO_REF:0000002, GO:0038096=Reactome:REACT_160123, GO:0005829=Reactome:REACT_160134} Q96JJ3 Engulfment and cell motility protein 2 protein 20130301 {GO:0005515=IPI, GO:0006909=IEA, GO:0030971=IPI, GO:0017124=IEA, GO:0005543=IEA, GO:0016020=IDA, GO:0060326=IMP, GO:0045087=TAS, GO:0006915=IEA, GO:0005856=IEA, GO:0038096=TAS, GO:0005829=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, apoptotic process, cell chemotaxis, innate immune response, phagocytosis cytoskeleton, cytosol, membrane SH3 domain binding, phospholipid binding, protein binding, receptor tyrosine kinase binding Human ELMO3 UniProtKB UniProtKB {GO:0006909=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0017124=GO_REF:0000037, GO:0005543=GO_REF:0000002, GO:0006915=GO_REF:0000037, GO:0005856=GO_REF:0000002} Q96BJ8 Engulfment and cell motility protein 3 protein 20130413 {GO:0006909=IEA, GO:0005737=IEA, GO:0017124=IEA, GO:0005543=IEA, GO:0006915=IEA, GO:0005856=IEA} apoptotic process, phagocytosis cytoplasm, cytoskeleton SH3 domain binding, phospholipid binding Human UniProtKB-SubCell:SL-0086 ELMOD1 HPA UniProtKB {GO:0043547=PMID:17452337, GO:0006909=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005856=GO_REF:0000002, GO:0005096=PMID:17452337} Q8N336 ELMO domain-containing protein 1 protein 20111111 {GO:0043547=IDA, GO:0006909=IEA, GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0005856=IEA, GO:0005096=IDA} phagocytosis, positive regulation of GTPase activity cytoplasm, cytoskeleton, nucleolus, nucleus GTPase activator activity Human ELMOD2 GOC UniProtKB {GO:0043547=PMID:17452337, GO:0050688=PMID:17452337, GO:0006909=GO_REF:0000002, GO:0051607=GO_REF:0000037, GO:0005856=GO_REF:0000002, GO:0005096=PMID:17452337} Q8IZ81 ELMO domain-containing protein 2 protein 20130413 {GO:0043547=IDA, GO:0050688=IDA, GO:0006909=IEA, GO:0051607=IEA, GO:0005856=IEA, GO:0005096=IDA} defense response to virus, phagocytosis, positive regulation of GTPase activity, regulation of defense response to virus cytoskeleton GTPase activator activity Human ELN BHF-UCL UniProtKB {GO:0005515=PMID:11805834, GO:0007585=PMID:9873040, GO:0008283=PMID:9607766, GO:0008015=PMID:8096434, GO:0043149=GO_REF:0000019, GO:0005578=GO_REF:0000029, GO:0050840=GO_REF:0000019, GO:0005576=Reactome:REACT_150459, GO:0030023=GO_REF:0000029, GO:0071953=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0030833=GO_REF:0000019, GO:0001974=GO_REF:0000019, GO:0007519=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0009887=PMID:9580666, GO:0005201=PMID:9580666} P15502 Elastin protein 20101007 {GO:0005515=IPI, GO:0007585=TAS, GO:0008283=TAS, GO:0008015=TAS, GO:0043149=IEA, GO:0005578=NAS, GO:0050840=IEA, GO:0005576=TAS, GO:0030023=NAS, GO:0071953=IEA, GO:0005739=IEA, GO:0030833=IEA, GO:0001974=IEA, GO:0007519=IEA, GO:0030198=TAS, GO:0009887=TAS, GO:0005201=TAS} blood circulation, blood vessel remodeling, cell proliferation, extracellular matrix organization, organ morphogenesis, regulation of actin filament polymerization, respiratory gaseous exchange, skeletal muscle tissue development, stress fiber assembly elastic fiber, extracellular region, mitochondrion, proteinaceous extracellular matrix extracellular matrix binding, extracellular matrix constituent conferring elasticity, extracellular matrix structural constituent, protein binding Human UniProtKB:Q9WVH8 ELOF1 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037} P60002 Transcription elongation factor 1 homolog protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0046872=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus metal ion binding Human UniProtKB-SubCell:SL-0191 ELOVL1 Reactome UniProtKB {GO:0005515=PMID:20937905, GO:0005783=PMID:20937905, GO:0019367=PMID:20166112, GO:0030148=PMID:20937905, GO:0030176=PMID:20166112, GO:0035338=Reactome:REACT_1319, GO:0044281=Reactome:REACT_111217, GO:0009922=PMID:20166112, GO:0005789=Reactome:REACT_22270, GO:0019432=Reactome:REACT_1190, GO:0034625=PMID:20166112, GO:0042761=PMID:20166112, GO:0044255=Reactome:REACT_22279} Q9BW60 Elongation of very long chain fatty acids protein 1 protein 20130301 {GO:0005515=IPI, GO:0005783=IDA, GO:0019367=IDA, GO:0030148=IMP, GO:0030176=NAS, GO:0035338=TAS, GO:0044281=TAS, GO:0009922=IDA, GO:0005789=TAS, GO:0019432=TAS, GO:0034625=IDA, GO:0042761=IDA, GO:0044255=TAS} cellular lipid metabolic process, fatty acid elongation, monounsaturated fatty acid, fatty acid elongation, saturated fatty acid, long-chain fatty-acyl-CoA biosynthetic process, small molecule metabolic process, sphingolipid biosynthetic process, triglyceride biosynthetic process, very long-chain fatty acid biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane fatty acid elongase activity, protein binding Human ELOVL2 Reactome UniProtKB {GO:0005515=PMID:20937905, GO:0005783=PMID:20937905, GO:0044281=Reactome:REACT_111217, GO:0035338=Reactome:REACT_1319, GO:0036109=Reactome:REACT_121147, GO:0033559=Reactome:REACT_121284, GO:0043651=Reactome:REACT_121100, GO:0009922=PMID:12371743, GO:0005789=Reactome:REACT_121099, GO:0019432=Reactome:REACT_1190, GO:0016021=GO_REF:0000037, GO:0034626=PMID:20937905, GO:0042761=PMID:20937905, GO:0044255=Reactome:REACT_22279} Q9NXB9 Elongation of very long chain fatty acids protein 2 protein 20130301 {GO:0005515=IPI, GO:0005783=IDA, GO:0044281=TAS, GO:0035338=TAS, GO:0036109=TAS, GO:0033559=TAS, GO:0043651=TAS, GO:0009922=IDA, GO:0005789=TAS, GO:0019432=TAS, GO:0016021=IEA, GO:0034626=IDA, GO:0042761=IDA, GO:0044255=TAS} alpha-linolenic acid metabolic process, cellular lipid metabolic process, fatty acid elongation, polyunsaturated fatty acid, linoleic acid metabolic process, long-chain fatty-acyl-CoA biosynthetic process, small molecule metabolic process, triglyceride biosynthetic process, unsaturated fatty acid metabolic process, very long-chain fatty acid biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane fatty acid elongase activity, protein binding Human ELOVL3 Reactome UniProtKB {GO:0005515=PMID:20937905, GO:0005783=PMID:20937905, GO:0019367=PMID:20937905, GO:0035338=Reactome:REACT_1319, GO:0044281=Reactome:REACT_111217, GO:0005789=Reactome:REACT_22133, GO:0019432=Reactome:REACT_1190, GO:0034625=PMID:20937905, GO:0016021=GO_REF:0000037, GO:0034626=PMID:20937905, GO:0042761=PMID:20937905, GO:0016740=GO_REF:0000037, GO:0044255=Reactome:REACT_22279} Q9HB03 Elongation of very long chain fatty acids protein 3 protein 20130301 {GO:0005515=IPI, GO:0005783=IDA, GO:0019367=IDA, GO:0035338=TAS, GO:0044281=TAS, GO:0005789=TAS, GO:0019432=TAS, GO:0034625=IDA, GO:0016021=IEA, GO:0034626=IDA, GO:0042761=IDA, GO:0016740=IEA, GO:0044255=TAS} cellular lipid metabolic process, fatty acid elongation, monounsaturated fatty acid, fatty acid elongation, polyunsaturated fatty acid, fatty acid elongation, saturated fatty acid, long-chain fatty-acyl-CoA biosynthetic process, small molecule metabolic process, triglyceride biosynthetic process, very long-chain fatty acid biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane protein binding, transferase activity Human ELOVL4 GOC UniProtKB {GO:0005515=PMID:20937905, GO:0005783=PMID:20937905, GO:0019367=PMID:20937905, GO:0030176=PMID:16036915, GO:0035338=Reactome:REACT_1319, GO:0044281=Reactome:REACT_111217, GO:0008020=PMID:11138005, GO:0009584=PMID:11138005, GO:0019432=Reactome:REACT_1190, GO:0006633=PMID:11138005, GO:0042761=GO_REF:0000024, GO:0016740=GO_REF:0000037, GO:0044255=Reactome:REACT_22279} Q9GZR5 Elongation of very long chain fatty acids protein 4 protein 20130413 {GO:0005515=IPI, GO:0005783=IDA, GO:0019367=IDA, GO:0030176=IDA, GO:0035338=TAS, GO:0044281=TAS, GO:0008020=NAS, GO:0009584=NAS, GO:0019432=TAS, GO:0006633=NAS, GO:0042761=ISS, GO:0016740=IEA, GO:0044255=TAS} cellular lipid metabolic process, detection of visible light, fatty acid biosynthetic process, fatty acid elongation, saturated fatty acid, long-chain fatty-acyl-CoA biosynthetic process, small molecule metabolic process, triglyceride biosynthetic process, very long-chain fatty acid biosynthetic process endoplasmic reticulum, integral to endoplasmic reticulum membrane G-protein coupled photoreceptor activity, protein binding, transferase activity Human ELOVL5 Reactome UniProtKB {GO:0005515=PMID:20937905, GO:0005783=PMID:20937905, GO:0044281=Reactome:REACT_111217, GO:0035338=Reactome:REACT_1319, GO:0036109=Reactome:REACT_121147, GO:0033559=Reactome:REACT_121284, GO:0043651=Reactome:REACT_121100, GO:0009922=PMID:20427700, GO:0005789=Reactome:REACT_121099, GO:0019432=Reactome:REACT_1190, GO:0034625=PMID:20427700, GO:0016021=GO_REF:0000037, GO:0034626=PMID:20937905, GO:0042761=PMID:20937905, GO:0044255=Reactome:REACT_22279} Q9NYP7 Elongation of very long chain fatty acids protein 5 protein 20130301 {GO:0005515=IPI, GO:0005783=IDA, GO:0044281=TAS, GO:0035338=TAS, GO:0036109=TAS, GO:0033559=TAS, GO:0043651=TAS, GO:0009922=IDA, GO:0005789=TAS, GO:0019432=TAS, GO:0034625=IDA, GO:0016021=IEA, GO:0034626=IDA, GO:0042761=IDA, GO:0044255=TAS} alpha-linolenic acid metabolic process, cellular lipid metabolic process, fatty acid elongation, monounsaturated fatty acid, fatty acid elongation, polyunsaturated fatty acid, linoleic acid metabolic process, long-chain fatty-acyl-CoA biosynthetic process, small molecule metabolic process, triglyceride biosynthetic process, unsaturated fatty acid metabolic process, very long-chain fatty acid biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane fatty acid elongase activity, protein binding Human ELOVL6 Reactome UniProtKB {GO:0005515=PMID:20937905, GO:0016747=GO_REF:0000019, GO:0005783=PMID:20937905, GO:0019367=PMID:20937905, GO:0030497=GO_REF:0000019, GO:0030176=GO_REF:0000019, GO:0035338=Reactome:REACT_1319, GO:0044281=Reactome:REACT_111217, GO:0042759=PMID:20937905, GO:0005789=Reactome:REACT_147888, GO:0019432=Reactome:REACT_1190, GO:0016021=GO_REF:0000002, GO:0044255=Reactome:REACT_22279} Q9H5J4 Elongation of very long chain fatty acids protein 6 protein 20130301 {GO:0005515=IPI, GO:0016747=IEA, GO:0005783=IDA, GO:0019367=IDA, GO:0030497=IEA, GO:0030176=IEA, GO:0035338=TAS, GO:0044281=TAS, GO:0042759=IDA, GO:0005789=TAS, GO:0019432=TAS, GO:0016021=IEA, GO:0044255=TAS} cellular lipid metabolic process, fatty acid elongation, fatty acid elongation, saturated fatty acid, long-chain fatty acid biosynthetic process, long-chain fatty-acyl-CoA biosynthetic process, small molecule metabolic process, triglyceride biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane, integral to membrane protein binding, transferase activity, transferring acyl groups other than amino-acyl groups Human ELOVL7 InterPro UniProtKB {GO:0005515=PMID:20937905, GO:0005783=PMID:20937905, GO:0019367=PMID:19826053, GO:0019432=Reactome:REACT_1190, GO:0005789=Reactome:REACT_22192, GO:0044281=Reactome:REACT_111217, GO:0035338=Reactome:REACT_1319, GO:0034626=PMID:20937905, GO:0016021=GO_REF:0000002, GO:0042761=PMID:19826053, GO:0044255=Reactome:REACT_22279, GO:0016740=GO_REF:0000037} D6RHD0 Elongation of very long chain fatty acids protein 7 protein 20130413 {GO:0005515=IPI, GO:0005783=IDA, GO:0019367=IDA, GO:0019432=TAS, GO:0005789=TAS, GO:0044281=TAS, GO:0035338=TAS, GO:0034626=IDA, GO:0016021=IEA, GO:0042761=IDA, GO:0044255=TAS, GO:0016740=IEA} cellular lipid metabolic process, fatty acid elongation, polyunsaturated fatty acid, fatty acid elongation, saturated fatty acid, long-chain fatty-acyl-CoA biosynthetic process, small molecule metabolic process, triglyceride biosynthetic process, very long-chain fatty acid biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane protein binding, transferase activity Human InterPro:IPR002076 ELP2 HPA UniProtKB {GO:0006368=PMID:11714725, GO:0005737=GO_REF:0000052, GO:0033588=PMID:22854966, GO:0006357=PMID:11714725, GO:0016591=PMID:11714725, GO:0005730=PMID:11714725, GO:0008023=PMID:11714725, GO:0003677=PMID:11714725} Q6IA86 Elongator complex protein 2 protein 20101115 {GO:0006368=IC, GO:0005737=IDA, GO:0033588=IDA, GO:0006357=TAS, GO:0016591=IC, GO:0005730=IC, GO:0008023=IDA, GO:0003677=IDA} regulation of transcription from RNA polymerase II promoter, transcription elongation from RNA polymerase II promoter DNA-directed RNA polymerase II, holoenzyme, Elongator holoenzyme complex, cytoplasm, nucleolus, transcription elongation factor complex DNA binding Human ELP3 IntAct UniProtKB {GO:0005515=PMID:19185337, GO:0006368=PMID:11714725, GO:0008080=GO_REF:0000002, GO:0030335=GO_REF:0000024, GO:0051536=GO_REF:0000037, GO:0006357=PMID:11714725, GO:0005730=PMID:11714725, GO:0008023=PMID:11714725, GO:0003677=PMID:11714725, GO:0046872=GO_REF:0000037, GO:0005737=GO_REF:0000054, GO:0033588=PMID:22854966, GO:0016591=PMID:11714725, GO:0008607=PMID:11818576, GO:0004402=GO_REF:0000003} Q9H9T3 Elongator complex protein 3 protein 20130415 {GO:0005515=IPI, GO:0006368=IDA, GO:0008080=IEA, GO:0030335=ISS, GO:0051536=IEA, GO:0006357=TAS, GO:0005730=IDA, GO:0008023=IDA, GO:0003677=IDA, GO:0046872=IEA, GO:0005737=IDA, GO:0033588=IDA, GO:0016591=IDA, GO:0008607=IDA, GO:0004402=IEA} positive regulation of cell migration, regulation of transcription from RNA polymerase II promoter, transcription elongation from RNA polymerase II promoter DNA-directed RNA polymerase II, holoenzyme, Elongator holoenzyme complex, cytoplasm, nucleolus, transcription elongation factor complex DNA binding, N-acetyltransferase activity, histone acetyltransferase activity, iron-sulfur cluster binding, metal ion binding, phosphorylase kinase regulator activity, protein binding Human UniProtKB:O95163 ELP4 GOC UniProtKB {GO:0005515=PMID:17577209, GO:0006368=PMID:11714725, GO:0005737=PMID:22854966, GO:0033588=PMID:11714725, GO:0016573=PMID:11714725, GO:0006357=PMID:11714725, GO:0016591=PMID:11714725, GO:0008607=PMID:11818576, GO:0008023=PMID:11714725, GO:0004402=PMID:11714725} Q96EB1 Elongator complex protein 4 protein 20130413 {GO:0005515=IPI, GO:0006368=IC, GO:0005737=IDA, GO:0033588=IDA, GO:0016573=IDA, GO:0006357=TAS, GO:0016591=IDA, GO:0008607=IDA, GO:0008023=IDA, GO:0004402=IDA} histone acetylation, regulation of transcription from RNA polymerase II promoter, transcription elongation from RNA polymerase II promoter DNA-directed RNA polymerase II, holoenzyme, Elongator holoenzyme complex, cytoplasm, transcription elongation factor complex histone acetyltransferase activity, phosphorylase kinase regulator activity, protein binding Human ELSPBP1 UniProtKB UniProtKB {GO:0007338=GO_REF:0000037, GO:0005576=GO_REF:0000039} Q96BH3 Epididymal sperm-binding protein 1 protein 20130413 {GO:0007338=IEA, GO:0005576=IEA} single fertilization extracellular region Human UniProtKB-SubCell:SL-0243 ELTD1 GDB UniProtKB {GO:0007186=PMID:15203201, GO:0005886=GO_REF:0000039, GO:0007218=GO_REF:0000002, GO:0004930=GO_REF:0000037, GO:0005509=GO_REF:0000002, GO:0046983=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q9HBW9 EGF, latrophilin and seven transmembrane domain-containing protein 1 protein 20050504 {GO:0007186=TAS, GO:0005886=IEA, GO:0007218=IEA, GO:0004930=IEA, GO:0005509=IEA, GO:0046983=IEA, GO:0016021=IEA} G-protein coupled receptor signaling pathway, neuropeptide signaling pathway integral to membrane, plasma membrane G-protein coupled receptor activity, calcium ion binding, protein dimerization activity Human EMB ENSEMBL UniProtKB {GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000019} Q6PCB8 Embigin protein 20130413 {GO:0016021=IEA, GO:0007155=IEA} cell adhesion integral to membrane Human Ensembl:ENSRNOP00000015306 EMC4 UniProtKB UniProtKB {GO:0072546=PMID:22119785, GO:0006915=GO_REF:0000037, GO:0016021=PMID:22119785} Q5J8M3 ER membrane protein complex subunit 4 protein 20120629 {GO:0072546=IDA, GO:0006915=IEA, GO:0016021=IDA} apoptotic process ER membrane protein complex, integral to membrane Human EMCN UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q9ULC0 Endomucin protein 20130413 {GO:0005886=IEA, GO:0005576=IEA, GO:0016021=IEA} extracellular region, integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 EMD HPA UniProtKB {GO:0007077=Reactome:REACT_160255, GO:0005515=PMID:16169070, GO:0031965=GO_REF:0000052, GO:0005783=GO_REF:0000052, GO:0007084=Reactome:REACT_160113, GO:0005874=GO_REF:0000037, GO:0048147=PMID:16858403, GO:0048487=PMID:17785515, GO:0005637=PMID:16858403, GO:0003779=PMID:15328537, GO:0005635=PMID:16858403, GO:0035914=GO_REF:0000019, GO:0035414=PMID:16858403, GO:0060828=PMID:16858403, GO:0046827=PMID:16858403, GO:0005640=PMID:17785515, GO:0006936=PMID:7894480, GO:0007517=PMID:8589715, GO:0071363=PMID:16858403, GO:0000088=Reactome:REACT_765, GO:0000087=Reactome:REACT_910, GO:0016021=GO_REF:0000037, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} Q5HY57 Emerin (Emery-Dreifuss muscular dystrophy), isoform CRA_b protein 20080205 {GO:0007077=TAS, GO:0005515=IPI, GO:0031965=IDA, GO:0005783=IDA, GO:0007084=TAS, GO:0005874=IEA, GO:0048147=IMP, GO:0048487=IDA, GO:0005637=NAS, GO:0003779=IDA, GO:0005635=IDA, GO:0035914=IEA, GO:0035414=IMP, GO:0060828=IMP, GO:0046827=IMP, GO:0005640=IDA, GO:0006936=TAS, GO:0007517=TAS, GO:0071363=IMP, GO:0000088=TAS, GO:0000087=TAS, GO:0016021=IEA, GO:0000278=TAS, GO:0000090=TAS} M phase of mitotic cell cycle, cellular response to growth factor stimulus, mitotic anaphase, mitotic cell cycle, mitotic nuclear envelope disassembly, mitotic nuclear envelope reassembly, mitotic prophase, muscle contraction, muscle organ development, negative regulation of catenin import into nucleus, negative regulation of fibroblast proliferation, positive regulation of protein export from nucleus, regulation of canonical Wnt receptor signaling pathway, skeletal muscle cell differentiation endoplasmic reticulum, integral to membrane, microtubule, nuclear envelope, nuclear inner membrane, nuclear membrane, nuclear outer membrane actin binding, beta-tubulin binding, protein binding Human EME1 IntAct UniProtKB {GO:0005515=PMID:19596236, GO:0004518=GO_REF:0000002, GO:0006281=GO_REF:0000037, GO:0004519=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0006310=GO_REF:0000037, GO:0006259=GO_REF:0000002, GO:0003677=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q96AY2 Crossover junction endonuclease EME1 protein 20130415 {GO:0005515=IPI, GO:0004518=IEA, GO:0006281=IEA, GO:0004519=IEA, GO:0005730=IEA, GO:0006310=IEA, GO:0006259=IEA, GO:0003677=IEA, GO:0046872=IEA} DNA metabolic process, DNA recombination, DNA repair nucleolus DNA binding, endonuclease activity, metal ion binding, nuclease activity, protein binding Human UniProtKB:Q8IY92 EME2 InterPro UniProtKB {GO:0004518=GO_REF:0000002, GO:0006281=GO_REF:0000037, GO:0004519=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006310=GO_REF:0000037, GO:0006259=GO_REF:0000002, GO:0003677=GO_REF:0000002} H3BV62 Probable crossover junction endonuclease EME2 protein 20130413 {GO:0004518=IEA, GO:0006281=IEA, GO:0004519=IEA, GO:0005634=IEA, GO:0006310=IEA, GO:0006259=IEA, GO:0003677=IEA} DNA metabolic process, DNA recombination, DNA repair nucleus DNA binding, endonuclease activity, nuclease activity Human InterPro:IPR006166 EMG1 UniProtKB UniProtKB {GO:0070037=PMID:20047967, GO:0005737=GO_REF:0000024, GO:0006364=GO_REF:0000024, GO:0003723=GO_REF:0000024, GO:0005730=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0042274=GO_REF:0000024, GO:0019843=GO_REF:0000037} Q92979 Ribosomal RNA small subunit methyltransferase NEP1 protein 20091117 {GO:0070037=IDA, GO:0005737=ISS, GO:0006364=ISS, GO:0003723=ISS, GO:0005730=ISS, GO:0005634=ISS, GO:0042274=ISS, GO:0019843=IEA} rRNA processing, ribosomal small subunit biogenesis cytoplasm, nucleolus, nucleus RNA binding, rRNA (pseudouridine) methyltransferase activity, rRNA binding Human UniProtKB:Q06287 EMID1 ENSEMBL UniProtKB {GO:0005581=GO_REF:0000037, GO:0005794=GO_REF:0000019, GO:0005783=GO_REF:0000019, GO:0005578=GO_REF:0000019} Q96A84 EMI domain-containing protein 1 protein 20130413 {GO:0005581=IEA, GO:0005794=IEA, GO:0005783=IEA, GO:0005578=IEA} Golgi apparatus, collagen, endoplasmic reticulum, proteinaceous extracellular matrix Human Ensembl:ENSMUSP00000061704 EMILIN1 Reactome UniProtKB {GO:0005515=PMID:11278945, GO:0005581=GO_REF:0000037, GO:0030198=Reactome:REACT_118779, GO:0010811=GO_REF:0000019, GO:0005576=Reactome:REACT_150335, GO:0030023=GO_REF:0000019, GO:0007155=GO_REF:0000037, GO:0042802=GO_REF:0000019} Q9Y6C2 EMILIN-1 protein 20130213 {GO:0005515=IPI, GO:0005581=IEA, GO:0030198=TAS, GO:0010811=IEA, GO:0005576=TAS, GO:0030023=IEA, GO:0007155=IEA, GO:0042802=IEA} cell adhesion, extracellular matrix organization, positive regulation of cell-substrate adhesion collagen, extracellular region extracellular matrix constituent conferring elasticity, identical protein binding, protein binding Human EMILIN2 UniProtKB UniProtKB {GO:0005515=PMID:11278945, GO:0008150=GO_REF:0000015, GO:0005581=GO_REF:0000037, GO:0030023=PMID:11278945, GO:0005576=PMID:11278945, GO:0007155=GO_REF:0000037} Q9BXX0 EMILIN-2 protein 20061026 {GO:0005515=IPI, GO:0008150=ND, GO:0005581=IEA, GO:0030023=NAS, GO:0005576=IDA, GO:0007155=IEA} biological_process, cell adhesion collagen, extracellular region extracellular matrix constituent conferring elasticity, protein binding Human EMILIN3 BHF-UCL UniProtKB {GO:0031012=PMID:22261194, GO:0005737=GO_REF:0000019, GO:0005578=GO_REF:0000039} Q9NT22 EMILIN-3 protein 20120228 {GO:0031012=ISS, GO:0005737=IEA, GO:0005578=IEA} cytoplasm, extracellular matrix, proteinaceous extracellular matrix colocalizes_with Human UniProtKB:F1SDV5 EML1 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0005737=GO_REF:0000037, GO:0005875=PMID:9226380, GO:0005509=PMID:9226380, GO:0005874=GO_REF:0000037} O00423 Echinoderm microtubule-associated protein-like 1 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0005875=TAS, GO:0005509=NAS, GO:0005874=IEA} cytoplasm, microtubule, microtubule associated complex calcium ion binding, protein binding Human UniProtKB:Q9H9L3 EML2 HPA UniProtKB {GO:0005737=GO_REF:0000037, GO:0005875=PMID:10521658, GO:0007605=PMID:10521658, GO:0005874=GO_REF:0000037, GO:0005102=GO_REF:0000019, GO:0008022=GO_REF:0000019, GO:0003824=GO_REF:0000002, GO:0007601=PMID:10521658, GO:0043231=GO_REF:0000052} O95834 Echinoderm microtubule-associated protein-like 2 protein 20081203 {GO:0005737=IEA, GO:0005875=TAS, GO:0007605=TAS, GO:0005874=IEA, GO:0005102=IEA, GO:0008022=IEA, GO:0003824=IEA, GO:0007601=TAS, GO:0043231=IDA} sensory perception of sound, visual perception cytoplasm, intracellular membrane-bounded organelle, microtubule, microtubule associated complex catalytic activity, protein C-terminus binding, receptor binding Human EML3 UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0005874=GO_REF:0000037} Q32P44 Echinoderm microtubule-associated protein-like 3 protein 20130413 {GO:0005737=IEA, GO:0005874=IEA} cytoplasm, microtubule Human UniProtKB-KW:KW-0493 EML4 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0007067=PMID:10995578, GO:0005737=PMID:10995578, GO:0005874=GO_REF:0000037, GO:0007017=PMID:10995578} Q9HC35 Echinoderm microtubule-associated protein-like 4 protein 20021114 {GO:0003674=ND, GO:0007067=NAS, GO:0005737=NAS, GO:0005874=IEA, GO:0007017=NAS} microtubule-based process, mitosis cytoplasm, microtubule molecular_function Human EMP2 MGI UniProtKB {GO:2001046=PMID:16216233, GO:0005178=PMID:16216233, GO:0008283=PMID:8996089, GO:0016021=GO_REF:0000037, GO:0001954=PMID:16216233} P54851 Epithelial membrane protein 2 protein 20130220 {GO:2001046=IDA, GO:0005178=IPI, GO:0008283=TAS, GO:0016021=IEA, GO:0001954=IDA} cell proliferation, positive regulation of cell-matrix adhesion, positive regulation of integrin-mediated signaling pathway integral to membrane integrin binding Human EMP3 PINC UniProtKB {GO:0008285=PMID:8996089, GO:0016020=GO_REF:0000002, GO:0016049=GO_REF:0000002, GO:0016021=GO_REF:0000037} P54852 Epithelial membrane protein 3 protein 20030904 {GO:0008285=TAS, GO:0016020=IEA, GO:0016049=IEA, GO:0016021=IEA} cell growth, negative regulation of cell proliferation integral to membrane, membrane Human EMR2 Reactome UniProtKB {GO:0031256=PMID:17928360, GO:0005886=Reactome:REACT_23776, GO:0004930=GO_REF:0000037, GO:0005509=GO_REF:0000002, GO:0071621=PMID:17928360, GO:0032587=GO_REF:0000039, GO:0035374=PMID:12829604, GO:0006954=GO_REF:0000037, GO:0007186=PMID:15203201, GO:0016020=GO_REF:0000002, GO:0016477=PMID:17928360, GO:0007218=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007155=PMID:12829604} Q9UHX3 EGF-like module-containing mucin-like hormone receptor-like 2 protein 20091026 {GO:0031256=IDA, GO:0005886=TAS, GO:0004930=IEA, GO:0005509=IEA, GO:0071621=IMP, GO:0032587=IEA, GO:0035374=IMP, GO:0006954=IEA, GO:0007186=TAS, GO:0016020=IEA, GO:0016477=IMP, GO:0007218=IEA, GO:0016021=IEA, GO:0007155=IMP} G-protein coupled receptor signaling pathway, cell adhesion, cell migration, granulocyte chemotaxis, inflammatory response, neuropeptide signaling pathway integral to membrane, leading edge membrane, membrane, plasma membrane, ruffle membrane G-protein coupled receptor activity, calcium ion binding, chondroitin sulfate binding Human EMX1 MGI UniProtKB {GO:0005515=PMID:20887964, GO:0043565=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0021796=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0042493=GO_REF:0000019, GO:0030182=GO_REF:0000019, GO:0007275=GO_REF:0000029, GO:0005634=PMID:20887964, GO:0009791=GO_REF:0000019, GO:0003677=GO_REF:0000029} Q04741 Homeobox protein EMX1 protein 20120406 {GO:0005515=IPI, GO:0043565=IEA, GO:0005737=IEA, GO:0021796=IEA, GO:0003700=IEA, GO:0042493=IEA, GO:0030182=IEA, GO:0007275=NAS, GO:0005634=IDA, GO:0009791=IEA, GO:0003677=NAS} cerebral cortex regionalization, multicellular organismal development, neuron differentiation, post-embryonic development, response to drug cytoplasm, nucleus DNA binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human EMX2 IntAct UniProtKB {GO:0005515=PMID:15247416, GO:0021542=GO_REF:0000019, GO:0021846=GO_REF:0000019, GO:0000976=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0042493=GO_REF:0000019, GO:0007275=GO_REF:0000029, GO:0005634=GO_REF:0000029, GO:0009952=GO_REF:0000019, GO:0003677=GO_REF:0000029, GO:0021796=GO_REF:0000019, GO:0030182=GO_REF:0000019, GO:0072001=GO_REF:0000019, GO:0021885=GO_REF:0000019} Q04743 Homeobox protein EMX2 protein 20130415 {GO:0005515=IPI, GO:0021542=IEA, GO:0021846=IEA, GO:0000976=IEA, GO:0003700=IEA, GO:0042493=IEA, GO:0007275=NAS, GO:0005634=NAS, GO:0009952=IEA, GO:0003677=NAS, GO:0021796=IEA, GO:0030182=IEA, GO:0072001=IEA, GO:0021885=IEA} anterior/posterior pattern specification, cell proliferation in forebrain, cerebral cortex regionalization, dentate gyrus development, forebrain cell migration, multicellular organismal development, neuron differentiation, renal system development, response to drug nucleus DNA binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding Human UniProtKB:P06730 EN1 PINC UniProtKB {GO:0003700=GO_REF:0000002, GO:0009954=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0009953=GO_REF:0000019, GO:0009653=PMID:8094370, GO:0043565=GO_REF:0000002, GO:0001501=PMID:8684466, GO:0048666=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0043473=GO_REF:0000019, GO:0030917=GO_REF:0000019, GO:0030901=GO_REF:0000019, GO:0035115=GO_REF:0000019, GO:0030902=GO_REF:0000019} Q05925 Homeobox protein engrailed-1 protein 20031119 {GO:0003700=IEA, GO:0009954=IEA, GO:0005634=IEA, GO:0009953=IEA, GO:0009653=TAS, GO:0043565=IEA, GO:0001501=TAS, GO:0048666=IEA, GO:0045944=IEA, GO:0043473=IEA, GO:0030917=IEA, GO:0030901=IEA, GO:0035115=IEA, GO:0030902=IEA} anatomical structure morphogenesis, dorsal/ventral pattern formation, embryonic forelimb morphogenesis, hindbrain development, midbrain development, midbrain-hindbrain boundary development, neuron development, pigmentation, positive regulation of transcription from RNA polymerase II promoter, proximal/distal pattern formation, skeletal system development nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human EN2 PINC UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0016020=GO_REF:0000019, GO:0048666=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0007275=PMID:1672471, GO:0005634=GO_REF:0000039, GO:0030901=GO_REF:0000019, GO:0030902=GO_REF:0000019} P19622 Homeobox protein engrailed-2 protein 20030904 {GO:0043565=IEA, GO:0003700=IEA, GO:0016020=IEA, GO:0048666=IEA, GO:0045944=IEA, GO:0007275=TAS, GO:0005634=IEA, GO:0030901=IEA, GO:0030902=IEA} hindbrain development, midbrain development, multicellular organismal development, neuron development, positive regulation of transcription from RNA polymerase II promoter membrane, nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human ENAH HPA UniProtKB {GO:0050852=Reactome:REACT_12526, GO:0001725=GO_REF:0000019, GO:0017124=GO_REF:0000019, GO:0030054=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0050699=PMID:17686488, GO:0001843=GO_REF:0000019, GO:0045202=GO_REF:0000039, GO:0046907=GO_REF:0000002, GO:0003779=GO_REF:0000037, GO:0030175=GO_REF:0000039, GO:0030027=GO_REF:0000039, GO:0005829=Reactome:REACT_19293, GO:0005737=GO_REF:0000052, GO:0008154=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0005925=GO_REF:0000052} Q8N8S7 Protein enabled homolog protein 20111111 {GO:0050852=TAS, GO:0001725=IEA, GO:0017124=IEA, GO:0030054=IDA, GO:0005886=IDA, GO:0050699=IPI, GO:0001843=IEA, GO:0045202=IEA, GO:0046907=IEA, GO:0003779=IEA, GO:0030175=IEA, GO:0030027=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0008154=IEA, GO:0007411=TAS, GO:0005925=IDA} T cell receptor signaling pathway, actin polymerization or depolymerization, axon guidance, intracellular transport, neural tube closure cell junction, cytoplasm, cytosol, filopodium, focal adhesion, lamellipodium, plasma membrane, stress fiber, synapse SH3 domain binding, WW domain binding, actin binding Human ENAM UniProtKB UniProtKB {GO:0030345=GO_REF:0000029, GO:0097186=GO_REF:0000019, GO:0005578=GO_REF:0000029, GO:0042476=GO_REF:0000029, GO:0030282=GO_REF:0000029} Q9NRM1 Enamelin protein 20030113 {GO:0030345=NAS, GO:0097186=IEA, GO:0005578=NAS, GO:0042476=NAS, GO:0030282=NAS} amelogenesis, bone mineralization, odontogenesis proteinaceous extracellular matrix structural constituent of tooth enamel Human ENC1 PINC UniProtKB {GO:0005515=PMID:19424503, GO:0017148=PMID:19424503, GO:0005737=PMID:19424503, GO:0016567=PMID:15983046, GO:0031463=PMID:15983046, GO:0007275=PMID:9566959, GO:0005634=PMID:9566959, GO:0003779=GO_REF:0000037, GO:0005856=GO_REF:0000039, GO:0016363=GO_REF:0000039, GO:0007399=PMID:9566959, GO:0010499=PMID:19424503} O14682 Ectoderm-neural cortex protein 1 protein 20030904 {GO:0005515=IPI, GO:0017148=IDA, GO:0005737=IDA, GO:0016567=IDA, GO:0031463=IDA, GO:0007275=TAS, GO:0005634=TAS, GO:0003779=IEA, GO:0005856=IEA, GO:0016363=IEA, GO:0007399=TAS, GO:0010499=IDA} multicellular organismal development, negative regulation of translation, nervous system development, proteasomal ubiquitin-independent protein catabolic process, protein ubiquitination Cul3-RING ubiquitin ligase complex, cytoplasm, cytoskeleton, nuclear matrix, nucleus actin binding, protein binding Human ENDOD1 UniProtKB UniProtKB {GO:0004519=GO_REF:0000037, GO:0005576=GO_REF:0000039, GO:0003676=GO_REF:0000002, GO:0046872=GO_REF:0000002} O94919 Endonuclease domain-containing 1 protein protein 20130413 {GO:0004519=IEA, GO:0005576=IEA, GO:0003676=IEA, GO:0046872=IEA} extracellular region endonuclease activity, metal ion binding, nucleic acid binding Human UniProtKB-SubCell:SL-0243 ENDOG UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0043065=GO_REF:0000019, GO:0004519=GO_REF:0000037, GO:0006309=GO_REF:0000019, GO:0034612=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0001701=GO_REF:0000019, GO:0046677=GO_REF:0000019, GO:0046872=GO_REF:0000037} Q14249 Endonuclease G, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0043065=IEA, GO:0004519=IEA, GO:0006309=IEA, GO:0034612=IEA, GO:0003676=IEA, GO:0001701=IEA, GO:0046677=IEA, GO:0046872=IEA} apoptotic DNA fragmentation, in utero embryonic development, positive regulation of apoptotic process, response to antibiotic, response to tumor necrosis factor mitochondrion endonuclease activity, metal ion binding, nucleic acid binding Human UniProtKB-SubCell:SL-0173 ENDOV UniProtKB UniProtKB {GO:0000287=GO_REF:0000024, GO:0006281=GO_REF:0000024, GO:0004519=GO_REF:0000002, GO:0016888=GO_REF:0000024} Q8N8Q3 Endonuclease V protein 20110516 {GO:0000287=ISS, GO:0006281=ISS, GO:0004519=IEA, GO:0016888=ISS} DNA repair endodeoxyribonuclease activity, producing 5'-phosphomonoesters, endonuclease activity, magnesium ion binding Human UniProtKB:Q8C9A2 ENG HPA UniProtKB {GO:0005515=PMID:20856203, GO:0005634=GO_REF:0000052, GO:0048844=PMID:8194490, GO:0005539=PMID:3262645, GO:0072563=GO_REF:0000019, GO:0048845=PMID:8194490, GO:0005615=PMID:19004009, GO:0042803=GO_REF:0000019, GO:0005114=PMID:8294451, GO:0001947=PMID:8194490, GO:0031953=PMID:12015308, GO:0030513=PMID:17068149, GO:0070022=PMID:1326540, GO:0005737=GO_REF:0000052, GO:0048185=PMID:11382917, GO:0048745=PMID:8194490, GO:0007155=GO_REF:0000037, GO:0017015=PMID:15702480, GO:0022009=PMID:7894484, GO:0050431=PMID:1326540, GO:0001569=PMID:8194490, GO:0006355=PMID:15702480, GO:0003273=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0010862=PMID:12015308, GO:0030509=PMID:11382917, GO:0005072=PMID:12015308, GO:0005534=PMID:3262645, GO:0034713=PMID:8294451, GO:0001300=GO_REF:0000019, GO:0001934=PMID:12015308, GO:0001570=PMID:7894484, GO:0009897=PMID:1537377, GO:0004888=PMID:18974388} P17813 Endoglin protein 20101115 {GO:0005515=IPI, GO:0005634=IDA, GO:0048844=ISS, GO:0005539=IDA, GO:0072563=IEA, GO:0048845=ISS, GO:0005615=IDA, GO:0042803=IEA, GO:0005114=ISS, GO:0001947=ISS, GO:0031953=IDA, GO:0030513=IDA, GO:0070022=IC, GO:0005737=IDA, GO:0048185=TAS, GO:0048745=ISS, GO:0007155=IEA, GO:0017015=IDA, GO:0022009=IMP, GO:0050431=IPI, GO:0001569=ISS, GO:0006355=IMP, GO:0003273=IEA, GO:0005730=IDA, GO:0010862=IDA, GO:0030509=TAS, GO:0005072=IDA, GO:0005534=IDA, GO:0034713=ISS, GO:0001300=IEA, GO:0001934=IDA, GO:0001570=IMP, GO:0009897=IDA, GO:0004888=NAS} BMP signaling pathway, artery morphogenesis, cell adhesion, cell migration involved in endocardial cushion formation, central nervous system vasculogenesis, chronological cell aging, heart looping, negative regulation of protein autophosphorylation, patterning of blood vessels, positive regulation of BMP signaling pathway, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of protein phosphorylation, regulation of transcription, DNA-dependent, regulation of transforming growth factor beta receptor signaling pathway, smooth muscle tissue development, vasculogenesis, venous blood vessel morphogenesis cytoplasm, endothelial microparticle, external side of plasma membrane, extracellular space, nucleolus, nucleus, transforming growth factor beta receptor homodimeric complex activin binding, galactose binding, glycosaminoglycan binding, protein binding, protein homodimerization activity, transforming growth factor beta binding, transforming growth factor beta receptor, cytoplasmic mediator activity, transmembrane signaling receptor activity, type I transforming growth factor beta receptor binding, type II transforming growth factor beta receptor binding Human ENGASE UniProtKB UniProtKB {GO:0005737=GO_REF:0000002, GO:0033925=GO_REF:0000003, GO:0005829=GO_REF:0000039} Q8NFI3 Cytosolic endo-beta-N-acetylglucosaminidase protein 20130413 {GO:0005737=IEA, GO:0033925=IEA, GO:0005829=IEA} cytoplasm, cytosol mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity Human UniProtKB-SubCell:SL-0091 ENKUR UniProtKB UniProtKB {GO:0005929=GO_REF:0000037, GO:0005516=GO_REF:0000037, GO:0017124=GO_REF:0000037} Q8TC29 Enkurin protein 20130413 {GO:0005929=IEA, GO:0005516=IEA, GO:0017124=IEA} cilium SH3 domain binding, calmodulin binding Human UniProtKB-KW:KW-0729 ENO1 BHF-UCL UniProtKB {GO:0005515=PMID:21274509, GO:0030308=PMID:10082554, GO:0003700=PMID:2005901, GO:0000287=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0005975=Reactome:REACT_474, GO:0003714=PMID:2005901, GO:0006094=Reactome:REACT_1520, GO:0005634=PMID:10082554, GO:0044281=Reactome:REACT_111217, GO:0000122=PMID:2005901, GO:0009615=PMID:16548883, GO:0003677=GO_REF:0000037, GO:0031430=GO_REF:0000039, GO:0004634=GO_REF:0000003, GO:0006096=Reactome:REACT_1383, GO:0006351=GO_REF:0000037, GO:0005829=Reactome:REACT_2018, GO:0005737=GO_REF:0000054, GO:0006006=Reactome:REACT_723, GO:0000015=GO_REF:0000002, GO:0045892=PMID:10082554} P06733 Alpha-enolase protein 20110222 {GO:0005515=IPI, GO:0030308=IDA, GO:0003700=TAS, GO:0000287=IEA, GO:0005886=IEA, GO:0005975=TAS, GO:0003714=TAS, GO:0006094=TAS, GO:0005634=IC, GO:0044281=TAS, GO:0000122=TAS, GO:0009615=IEP, GO:0003677=IEA, GO:0031430=IEA, GO:0004634=IEA, GO:0006096=TAS, GO:0006351=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0006006=TAS, GO:0000015=IEA, GO:0045892=IDA} carbohydrate metabolic process, gluconeogenesis, glucose metabolic process, glycolysis, negative regulation of cell growth, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, response to virus, small molecule metabolic process, transcription, DNA-dependent M band, cytoplasm, cytosol, nucleus, phosphopyruvate hydratase complex, plasma membrane DNA binding, magnesium ion binding, phosphopyruvate hydratase activity, protein binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human UniProtKB:O75952-1 ENO2 Reactome UniProtKB {GO:0001917=GO_REF:0000019, GO:0000287=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0005975=Reactome:REACT_474, GO:0006094=Reactome:REACT_1520, GO:0006006=Reactome:REACT_723, GO:0043204=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0000015=GO_REF:0000002, GO:0006096=Reactome:REACT_1383, GO:0004634=GO_REF:0000003, GO:0005829=Reactome:REACT_2018} P09104 Gamma-enolase protein 20130213 {GO:0001917=IEA, GO:0000287=IEA, GO:0005886=IEA, GO:0005975=TAS, GO:0006094=TAS, GO:0006006=TAS, GO:0043204=IEA, GO:0044281=TAS, GO:0000015=IEA, GO:0006096=TAS, GO:0004634=IEA, GO:0005829=TAS} carbohydrate metabolic process, gluconeogenesis, glucose metabolic process, glycolysis, small molecule metabolic process cytosol, perikaryon, phosphopyruvate hydratase complex, photoreceptor inner segment, plasma membrane magnesium ion binding, phosphopyruvate hydratase activity Human ENO3 HPA UniProtKB {GO:0000287=GO_REF:0000002, GO:0046982=GO_REF:0000019, GO:0005975=Reactome:REACT_474, GO:0042493=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0006094=Reactome:REACT_1520, GO:0044281=Reactome:REACT_111217, GO:0006096=Reactome:REACT_1383, GO:0004634=GO_REF:0000003, GO:0042803=GO_REF:0000019, GO:0005829=Reactome:REACT_2018, GO:0005737=GO_REF:0000052, GO:0016020=GO_REF:0000019, GO:0006006=Reactome:REACT_723, GO:0043403=GO_REF:0000019, GO:0000015=GO_REF:0000002} P13929 Beta-enolase protein 20080205 {GO:0000287=IEA, GO:0046982=IEA, GO:0005975=TAS, GO:0042493=IEA, GO:0007568=IEA, GO:0006094=TAS, GO:0044281=TAS, GO:0006096=TAS, GO:0004634=IEA, GO:0042803=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0016020=IEA, GO:0006006=TAS, GO:0043403=IEA, GO:0000015=IEA} aging, carbohydrate metabolic process, gluconeogenesis, glucose metabolic process, glycolysis, response to drug, skeletal muscle tissue regeneration, small molecule metabolic process cytoplasm, cytosol, membrane, phosphopyruvate hydratase complex magnesium ion binding, phosphopyruvate hydratase activity, protein heterodimerization activity, protein homodimerization activity Human ENOPH1 Reactome UniProtKB {GO:0008967=GO_REF:0000002, GO:0034641=Reactome:REACT_13, GO:0000096=Reactome:REACT_115639, GO:0000287=GO_REF:0000002, GO:0019509=Reactome:REACT_75881, GO:0006595=Reactome:REACT_14820, GO:0005634=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0005575=GO_REF:0000015, GO:0005829=Reactome:REACT_75868, GO:0043874=Reactome:REACT_75868} Q9UHY7 Enolase-phosphatase E1 protein 20110330 {GO:0008967=IEA, GO:0034641=TAS, GO:0000096=TAS, GO:0000287=IEA, GO:0019509=TAS, GO:0006595=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0005575=ND, GO:0005829=TAS, GO:0043874=TAS} L-methionine salvage from methylthioadenosine, cellular nitrogen compound metabolic process, polyamine metabolic process, small molecule metabolic process, sulfur amino acid metabolic process cellular_component, cytosol, nucleus acireductone synthase activity, magnesium ion binding, phosphoglycolate phosphatase activity Human ENOSF1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0016853=GO_REF:0000037, GO:0009063=GO_REF:0000002, GO:0003824=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q7L5Y1 Mitochondrial enolase superfamily member 1 protein 20090723 {GO:0005739=IEA, GO:0003674=ND, GO:0008150=ND, GO:0005575=ND, GO:0016853=IEA, GO:0009063=IEA, GO:0003824=IEA, GO:0046872=IEA} biological_process, cellular amino acid catabolic process cellular_component, mitochondrion catalytic activity, isomerase activity, metal ion binding, molecular_function Human ENOX1 HPA UniProtKB {GO:0005886=GO_REF:0000052, GO:0000166=GO_REF:0000002, GO:0016491=GO_REF:0000037, GO:0048511=GO_REF:0000037, GO:0022900=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0005615=GO_REF:0000039} Q8TC92 Ecto-NOX disulfide-thiol exchanger 1 protein 20110516 {GO:0005886=IDA, GO:0000166=IEA, GO:0016491=IEA, GO:0048511=IEA, GO:0022900=IEA, GO:0003676=IEA, GO:0005615=IEA} electron transport chain, rhythmic process extracellular space, plasma membrane nucleic acid binding, nucleotide binding, oxidoreductase activity Human ENOX2 PINC UniProtKB {GO:0000166=GO_REF:0000002, GO:0015035=PMID:1888291, GO:0007624=PMID:12356293, GO:0016049=PMID:9932650, GO:0022900=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0005615=GO_REF:0000039, GO:0009897=PMID:11488599, GO:0040008=GO_REF:0000037, GO:0005829=PMID:8150545, GO:0055114=PMID:11888291} Q16206 Ecto-NOX disulfide-thiol exchanger 2 protein 20030904 {GO:0000166=IEA, GO:0015035=IDA, GO:0007624=IDA, GO:0016049=NAS, GO:0022900=IEA, GO:0003676=IEA, GO:0005615=IEA, GO:0009897=IDA, GO:0040008=IEA, GO:0005829=TAS, GO:0055114=IDA} cell growth, electron transport chain, oxidation-reduction process, regulation of growth, ultradian rhythm cytosol, external side of plasma membrane, extracellular space nucleic acid binding, nucleotide binding, protein disulfide oxidoreductase activity Human ENPEP Reactome UniProtKB {GO:0005886=Reactome:REACT_147872, GO:0002003=Reactome:REACT_147707, GO:0008283=PMID:14998491, GO:0007267=PMID:8346219, GO:0045177=GO_REF:0000024, GO:0001525=GO_REF:0000024, GO:0031410=GO_REF:0000024, GO:0032835=GO_REF:0000024, GO:0005903=GO_REF:0000024, GO:0003081=PMID:19608358, GO:0016324=GO_REF:0000024, GO:0016477=PMID:14998491, GO:0005887=PMID:8244382, GO:0004177=PMID:8244382, GO:0006508=GO_REF:0000037, GO:0070006=PMID:8346219, GO:0002005=PMID:19608358, GO:0008270=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0008237=Reactome:REACT_147872, GO:0009897=GO_REF:0000024} Q07075 Glutamyl aminopeptidase protein 20111129 {GO:0005886=TAS, GO:0002003=TAS, GO:0008283=IDA, GO:0007267=NAS, GO:0045177=ISS, GO:0001525=ISS, GO:0031410=ISS, GO:0032835=ISS, GO:0005903=ISS, GO:0003081=IDA, GO:0016324=ISS, GO:0016477=IDA, GO:0005887=NAS, GO:0004177=IDA, GO:0006508=IEA, GO:0070006=IDA, GO:0002005=NAS, GO:0008270=IEA, GO:0044267=TAS, GO:0008237=EXP, GO:0009897=ISS} angiogenesis, angiotensin catabolic process in blood, angiotensin maturation, cell migration, cell proliferation, cell-cell signaling, cellular protein metabolic process, glomerulus development, proteolysis, regulation of systemic arterial blood pressure by renin-angiotensin apical part of cell, apical plasma membrane, brush border, cytoplasmic vesicle, external side of plasma membrane, integral to plasma membrane, plasma membrane aminopeptidase activity, metalloaminopeptidase activity, metallopeptidase activity, zinc ion binding Human ENPP1 BHF-UCL UniProtKB {GO:0005515=PMID:11289049, GO:0030308=PMID:17849011, GO:0050427=PMID:7830796, GO:0005886=PMID:10513816, GO:0045599=PMID:17849011, GO:0005158=PMID:7830796, GO:0004551=PMID:12746903, GO:0006767=Reactome:REACT_11238, GO:0009143=PMID:10513816, GO:0006091=PMID:12746903, GO:0044281=Reactome:REACT_111217, GO:0006796=PMID:11159191, GO:0003824=GO_REF:0000002, GO:0005615=PMID:11159191, GO:0042803=PMID:7830796, GO:0046872=GO_REF:0000037, GO:0031953=PMID:11289049, GO:0016323=PMID:9553761, GO:0006771=Reactome:REACT_11070, GO:0030279=GO_REF:0000019, GO:0006955=GO_REF:0000002, GO:0030730=PMID:17849011, GO:0004528=GO_REF:0000003, GO:0046849=GO_REF:0000019, GO:0046325=PMID:17849011, GO:0005044=GO_REF:0000002, GO:0032869=PMID:17849011, GO:0030500=PMID:10513816, GO:0009986=PMID:10513816, GO:0046627=PMID:17849011, GO:0050656=PMID:7830796, GO:0003676=GO_REF:0000002, GO:0005524=PMID:7830796, GO:0031214=GO_REF:0000037, GO:0045719=PMID:11289049, GO:0030505=PMID:10513816, GO:0030643=PMID:11159191, GO:0006766=Reactome:REACT_11193, GO:0047429=PMID:11159191, GO:0030247=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0035529=GO_REF:0000003} P22413 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 protein 20080219 {GO:0005515=IPI, GO:0030308=IDA, GO:0050427=IDA, GO:0005886=IDA, GO:0045599=IDA, GO:0005158=IDA, GO:0004551=IDA, GO:0006767=TAS, GO:0009143=IDA, GO:0006091=IDA, GO:0044281=TAS, GO:0006796=IDA, GO:0003824=IEA, GO:0005615=IDA, GO:0042803=IDA, GO:0046872=IEA, GO:0031953=IDA, GO:0016323=NAS, GO:0006771=TAS, GO:0030279=IEA, GO:0006955=IEA, GO:0030730=IDA, GO:0004528=IEA, GO:0046849=IEA, GO:0046325=IDA, GO:0005044=IEA, GO:0032869=IDA, GO:0030500=IC, GO:0009986=IDA, GO:0046627=IDA, GO:0050656=IC, GO:0003676=IEA, GO:0005524=IDA, GO:0031214=IEA, GO:0045719=IDA, GO:0030505=IDA, GO:0030643=IDA, GO:0006766=TAS, GO:0047429=IDA, GO:0030247=IEA, GO:0016021=IEA, GO:0035529=IEA} 3'-phosphoadenosine 5'-phosphosulfate metabolic process, biomineral tissue development, bone remodeling, cellular phosphate ion homeostasis, cellular response to insulin stimulus, generation of precursor metabolites and energy, immune response, inorganic diphosphate transport, negative regulation of cell growth, negative regulation of fat cell differentiation, negative regulation of glucose import, negative regulation of glycogen biosynthetic process, negative regulation of insulin receptor signaling pathway, negative regulation of ossification, negative regulation of protein autophosphorylation, nucleoside triphosphate catabolic process, phosphate-containing compound metabolic process, regulation of bone mineralization, riboflavin metabolic process, sequestering of triglyceride, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process basolateral plasma membrane, cell surface, extracellular space, integral to membrane, plasma membrane 3'-phosphoadenosine 5'-phosphosulfate binding, ATP binding, NADH pyrophosphatase activity, catalytic activity, insulin receptor binding, metal ion binding, nucleic acid binding, nucleoside-triphosphate diphosphatase activity, nucleotide diphosphatase activity, phosphodiesterase I activity, polysaccharide binding, protein binding, protein homodimerization activity, scavenger receptor activity Human ENPP2 PINC UniProtKB {GO:0030334=PMID:1733949, GO:0005886=PMID:8579579, GO:0005509=GO_REF:0000024, GO:0004551=PMID:8579579, GO:0006928=PMID:1733949, GO:0006796=PMID:8579579, GO:0003676=GO_REF:0000002, GO:0003824=GO_REF:0000002, GO:0005615=GO_REF:0000024, GO:0046872=GO_REF:0000002, GO:0006955=GO_REF:0000002, GO:0004528=PMID:7982964, GO:0007186=PMID:1733949, GO:0016787=PMID:7982964, GO:0006935=PMID:7982964, GO:0005887=PMID:1733949, GO:0004622=PMID:21240271, GO:0030247=GO_REF:0000002, GO:0047391=GO_REF:0000003, GO:0008270=GO_REF:0000024, GO:0034638=PMID:21240271, GO:0008134=PMID:8586446, GO:0005044=GO_REF:0000002} Q13822 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 protein 20030904 {GO:0030334=IDA, GO:0005886=TAS, GO:0005509=ISS, GO:0004551=TAS, GO:0006928=TAS, GO:0006796=TAS, GO:0003676=IEA, GO:0003824=IEA, GO:0005615=ISS, GO:0046872=IEA, GO:0006955=IEA, GO:0004528=TAS, GO:0007186=TAS, GO:0016787=TAS, GO:0006935=NAS, GO:0005887=TAS, GO:0004622=IDA, GO:0030247=IEA, GO:0047391=IEA, GO:0008270=ISS, GO:0034638=IDA, GO:0008134=TAS, GO:0005044=IEA} G-protein coupled receptor signaling pathway, cellular component movement, chemotaxis, immune response, phosphate-containing compound metabolic process, phosphatidylcholine catabolic process, regulation of cell migration extracellular space, integral to plasma membrane, plasma membrane alkylglycerophosphoethanolamine phosphodiesterase activity, calcium ion binding, catalytic activity, hydrolase activity, lysophospholipase activity, metal ion binding, nucleic acid binding, nucleotide diphosphatase activity, phosphodiesterase I activity, polysaccharide binding, scavenger receptor activity, transcription factor binding, zinc ion binding Human ENPP3 BHF-UCL UniProtKB {GO:0048471=PMID:10513816, GO:0004551=PMID:9344668, GO:0005576=GO_REF:0000039, GO:0009143=PMID:10513816, GO:0006796=PMID:10513816, GO:0003824=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0030505=PMID:10513816, GO:0006955=GO_REF:0000002, GO:0004528=GO_REF:0000003, GO:0047429=PMID:10513816, GO:0005887=PMID:9344668, GO:0030247=GO_REF:0000002, GO:0035529=GO_REF:0000003, GO:0005044=GO_REF:0000002} O14638 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 protein 20080225 {GO:0048471=IDA, GO:0004551=TAS, GO:0005576=IEA, GO:0009143=IDA, GO:0006796=IDA, GO:0003824=IEA, GO:0003676=IEA, GO:0046872=IEA, GO:0030505=IDA, GO:0006955=IEA, GO:0004528=IEA, GO:0047429=IDA, GO:0005887=TAS, GO:0030247=IEA, GO:0035529=IEA, GO:0005044=IEA} immune response, inorganic diphosphate transport, nucleoside triphosphate catabolic process, phosphate-containing compound metabolic process extracellular region, integral to plasma membrane, perinuclear region of cytoplasm NADH pyrophosphatase activity, catalytic activity, metal ion binding, nucleic acid binding, nucleoside-triphosphate diphosphatase activity, nucleotide diphosphatase activity, phosphodiesterase I activity, polysaccharide binding, scavenger receptor activity Human ENPP7 Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0006684=PMID:12671034, GO:0008285=PMID:12671034, GO:0005794=PMID:12671034, GO:0005886=Reactome:REACT_115560, GO:0006687=Reactome:REACT_116105, GO:0004767=PMID:12671034, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0005902=PMID:12671034, GO:0016020=PMID:12885774, GO:0016021=GO_REF:0000037, GO:0008156=PMID:12671034} Q6UWV6 Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 protein 20130301 {GO:0006665=TAS, GO:0006684=IDA, GO:0008285=IDA, GO:0005794=IDA, GO:0005886=TAS, GO:0006687=TAS, GO:0004767=IDA, GO:0044281=TAS, GO:0003824=IEA, GO:0005902=IDA, GO:0016020=NAS, GO:0016021=IEA, GO:0008156=IDA} glycosphingolipid metabolic process, negative regulation of DNA replication, negative regulation of cell proliferation, small molecule metabolic process, sphingolipid metabolic process, sphingomyelin metabolic process Golgi apparatus, integral to membrane, membrane, microvillus, plasma membrane catalytic activity, sphingomyelin phosphodiesterase activity Human ENSA Reactome UniProtKB {GO:0007584=PMID:9653196, GO:0004864=GO_REF:0000037, GO:0008601=GO_REF:0000024, GO:0005102=PMID:9653196, GO:0019212=GO_REF:0000024, GO:0009749=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0007067=GO_REF:0000024, GO:0000088=Reactome:REACT_765, GO:0000086=GO_REF:0000024, GO:0000087=Reactome:REACT_910, GO:0006810=PMID:9653196, GO:0005654=Reactome:REACT_150207, GO:0000278=Reactome:REACT_152, GO:0008200=PMID:9653196, GO:0051721=GO_REF:0000024, GO:0051301=GO_REF:0000037} O43768 Alpha-endosulfine protein 20120306 {GO:0007584=TAS, GO:0004864=IEA, GO:0008601=ISS, GO:0005102=TAS, GO:0019212=ISS, GO:0009749=IEA, GO:0005737=IEA, GO:0007067=ISS, GO:0000088=TAS, GO:0000086=ISS, GO:0000087=TAS, GO:0006810=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0008200=TAS, GO:0051721=ISS, GO:0051301=IEA} G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, cell division, mitosis, mitotic cell cycle, mitotic prophase, response to glucose stimulus, response to nutrient, transport cytoplasm, nucleoplasm ion channel inhibitor activity, phosphatase inhibitor activity, protein phosphatase 2A binding, protein phosphatase inhibitor activity, protein phosphatase type 2A regulator activity, receptor binding Human ENTHD1 null null {} null null null null {} null null null ENTPD1 PINC UniProtKB {GO:0005886=PMID:8955160, GO:0016787=GO_REF:0000037, GO:0007596=PMID:8955160, GO:0005887=PMID:7930580, GO:0007155=PMID:7930580, GO:0005524=GO_REF:0000037} P49961 Ectonucleoside triphosphate diphosphohydrolase 1 protein 20030904 {GO:0005886=NAS, GO:0016787=IEA, GO:0007596=TAS, GO:0005887=TAS, GO:0007155=NAS, GO:0005524=IEA} blood coagulation, cell adhesion integral to plasma membrane, plasma membrane ATP binding, hydrolase activity Human ENTPD2 ENSEMBL UniProtKB {GO:0017111=GO_REF:0000019, GO:0017110=GO_REF:0000019, GO:0007186=GO_REF:0000019, GO:0009181=GO_REF:0000019, GO:0005605=GO_REF:0000019, GO:0030168=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q9Y5L3 Ectonucleoside triphosphate diphosphohydrolase 2 protein 20130413 {GO:0017111=IEA, GO:0017110=IEA, GO:0007186=IEA, GO:0009181=IEA, GO:0005605=IEA, GO:0030168=IEA, GO:0016021=IEA, GO:0005524=IEA} G-protein coupled receptor signaling pathway, platelet activation, purine ribonucleoside diphosphate catabolic process basal lamina, integral to membrane ATP binding, nucleoside-diphosphatase activity, nucleoside-triphosphatase activity Human Ensembl:ENSMUSP00000028328 ENTPD4 HPA UniProtKB {GO:0030173=PMID:9556635, GO:0005737=GO_REF:0000052, GO:0016787=GO_REF:0000038, GO:0045134=PMID:9556635, GO:0000421=GO_REF:0000039, GO:0031410=GO_REF:0000037, GO:0006256=PMID:9556635, GO:0043231=GO_REF:0000052} Q9Y227 Ectonucleoside triphosphate diphosphohydrolase 4 protein 20090616 {GO:0030173=IDA, GO:0005737=IDA, GO:0016787=IEA, GO:0045134=IDA, GO:0000421=IEA, GO:0031410=IEA, GO:0006256=IDA, GO:0043231=IDA} UDP catabolic process autophagic vacuole membrane, cytoplasm, cytoplasmic vesicle, integral to Golgi membrane, intracellular membrane-bounded organelle hydrolase activity, uridine-diphosphatase activity Human ENTPD5 UniProtKB UniProtKB {GO:0046034=GO_REF:0000024, GO:0004382=GO_REF:0000024, GO:0005783=GO_REF:0000024, GO:0008283=GO_REF:0000024, GO:0014066=GO_REF:0000024, GO:0006096=GO_REF:0000024, GO:0016787=GO_REF:0000002, GO:0045134=GO_REF:0000024, GO:0005789=GO_REF:0000039, GO:0016049=GO_REF:0000024, GO:0051084=GO_REF:0000024, GO:0006487=GO_REF:0000024, GO:0016021=GO_REF:0000037} O75356 Ectonucleoside triphosphate diphosphohydrolase 5 protein 20101217 {GO:0046034=ISS, GO:0004382=ISS, GO:0005783=ISS, GO:0008283=ISS, GO:0014066=ISS, GO:0006096=ISS, GO:0016787=IEA, GO:0045134=ISS, GO:0005789=IEA, GO:0016049=ISS, GO:0051084=ISS, GO:0006487=ISS, GO:0016021=IEA} 'de novo' posttranslational protein folding, ATP metabolic process, cell growth, cell proliferation, glycolysis, protein N-linked glycosylation, regulation of phosphatidylinositol 3-kinase cascade endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane guanosine-diphosphatase activity, hydrolase activity, uridine-diphosphatase activity Human UniProtKB:Q9WUZ9 ENTPD6 InterPro UniProtKB {GO:0051592=GO_REF:0000019, GO:0017111=GO_REF:0000019, GO:0000139=GO_REF:0000039, GO:0009986=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0016787=GO_REF:0000002, GO:0045134=GO_REF:0000003, GO:0032026=GO_REF:0000019, GO:0008894=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0005615=GO_REF:0000019} Q5QPJ7 Ectonucleoside triphosphate diphosphohydrolase 6 protein 20130413 {GO:0051592=IEA, GO:0017111=IEA, GO:0000139=IEA, GO:0009986=IEA, GO:0005886=IEA, GO:0016787=IEA, GO:0045134=IEA, GO:0032026=IEA, GO:0008894=IEA, GO:0016021=IEA, GO:0005615=IEA} response to calcium ion, response to magnesium ion Golgi membrane, cell surface, extracellular space, integral to membrane, plasma membrane guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity, hydrolase activity, nucleoside-triphosphatase activity, uridine-diphosphatase activity Human InterPro:IPR000407 ENY2 UniProtKB UniProtKB {GO:0016578=PMID:18206972, GO:0030374=PMID:18206972, GO:0000124=PMID:18206972, GO:0003713=PMID:18206972, GO:0051028=GO_REF:0000037, GO:0045893=PMID:18206972, GO:0006351=GO_REF:0000037} Q9NPA8 Enhancer of yellow 2 transcription factor homolog protein 20090427 {GO:0016578=IDA, GO:0030374=IDA, GO:0000124=IDA, GO:0003713=IDA, GO:0051028=IEA, GO:0045893=IDA, GO:0006351=IEA} histone deubiquitination, mRNA transport, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent SAGA complex ligand-dependent nuclear receptor transcription coactivator activity, transcription coactivator activity Human EOMES BHF-UCL UniProtKB {GO:0001191=GO_REF:0000024, GO:0003700=GO_REF:0000002, GO:0045597=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0001714=GO_REF:0000019, GO:0021772=GO_REF:0000019, GO:0045944=PMID:20713518, GO:0002302=PMID:17566017, GO:0032609=GO_REF:0000019, GO:0021895=GO_REF:0000019, GO:0001102=GO_REF:0000024, GO:0001706=GO_REF:0000024, GO:0000977=GO_REF:0000019, GO:0001707=GO_REF:0000024, GO:0060706=GO_REF:0000024, GO:0000122=GO_REF:0000024, GO:0001829=GO_REF:0000019, GO:0060809=GO_REF:0000024, GO:0003677=GO_REF:0000024, GO:0006351=GO_REF:0000038, GO:0043565=PMID:20713518, GO:0007420=PMID:17353897, GO:0019827=GO_REF:0000019, GO:0045664=GO_REF:0000019, GO:0045893=GO_REF:0000024} O95936 Eomesodermin homolog protein 20121106 {GO:0001191=ISS, GO:0003700=IEA, GO:0045597=IEA, GO:0005634=IEA, GO:0001714=IEA, GO:0021772=IEA, GO:0045944=IDA, GO:0002302=IMP, GO:0032609=IEA, GO:0021895=IEA, GO:0001102=ISS, GO:0001706=ISS, GO:0000977=IEA, GO:0001707=ISS, GO:0060706=ISS, GO:0000122=ISS, GO:0001829=IEA, GO:0060809=ISS, GO:0003677=ISS, GO:0006351=IEA, GO:0043565=IDA, GO:0007420=IMP, GO:0019827=IEA, GO:0045664=IEA, GO:0045893=ISS} CD8-positive, alpha-beta T cell differentiation involved in immune response, brain development, cell differentiation involved in embryonic placenta development, cerebral cortex neuron differentiation, endoderm formation, endodermal cell fate specification, interferon-gamma production, mesoderm formation, mesodermal to mesenchymal transition involved in gastrulation, negative regulation of transcription from RNA polymerase II promoter, olfactory bulb development, positive regulation of cell differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of neuron differentiation, stem cell maintenance, transcription, DNA-dependent, trophectodermal cell differentiation nucleus DNA binding, RNA polymerase II activating transcription factor binding, RNA polymerase II regulatory region sequence-specific DNA binding, RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:O54839 EP300 HPA UniProtKB {GO:0005515=PMID:22770219, GO:0043627=PMID:11581164, GO:0008013=PMID:12408825, GO:0001756=GO_REF:0000019, GO:0018076=PMID:12435739, GO:0050681=PMID:18487222, GO:0007507=GO_REF:0000019, GO:0004468=PMID:20019387, GO:0007219=Reactome:REACT_118859, GO:0000123=GO_REF:0000019, GO:0009887=GO_REF:0000019, GO:0001102=PMID:20018936, GO:0003713=PMID:18487222, GO:0060765=PMID:18487222, GO:0033554=Reactome:REACT_120956, GO:0000122=PMID:10733570, GO:0031490=GO_REF:0000019, GO:0043923=PMID:16687403, GO:0018393=PMID:17403783, GO:0042771=PMID:17403783, GO:0007049=GO_REF:0000037, GO:0007519=GO_REF:0000019, GO:0043967=PMID:16325578, GO:0045087=Reactome:REACT_6802, GO:0016407=PMID:12435739, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_160309, GO:0008134=PMID:15261140, GO:0016746=PMID:17403783, GO:0030324=GO_REF:0000019, GO:0061418=Reactome:REACT_120815, GO:0005634=GO_REF:0000052, GO:0032092=GO_REF:0000019, GO:0002039=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0051091=PMID:10518217, GO:0045944=PMID:12586840, GO:0033613=PMID:20590529, GO:0004402=PMID:12040021, GO:0001666=PMID:9887100, GO:0005667=GO_REF:0000019, GO:0006355=PMID:15261140, GO:0005730=GO_REF:0000052, GO:0006915=PMID:9194565, GO:0071456=Reactome:REACT_121311, GO:0003677=PMID:9194565, GO:0006351=GO_REF:0000037, GO:0007399=PMID:10205054, GO:0019048=GO_REF:0000037, GO:0003682=PMID:17641689} Q09472 Histone acetyltransferase p300 protein 20120912 {GO:0005515=IPI, GO:0043627=IDA, GO:0008013=IPI, GO:0001756=IEA, GO:0018076=IDA, GO:0050681=IPI, GO:0007507=IEA, GO:0004468=IDA, GO:0007219=TAS, GO:0000123=IEA, GO:0009887=IEA, GO:0001102=IPI, GO:0003713=IDA, GO:0060765=IDA, GO:0033554=TAS, GO:0000122=IDA, GO:0031490=IEA, GO:0043923=IDA, GO:0018393=IDA, GO:0042771=IDA, GO:0007049=IEA, GO:0007519=IEA, GO:0043967=IMP, GO:0045087=TAS, GO:0016407=IMP, GO:0008270=IEA, GO:0005654=TAS, GO:0008134=IPI, GO:0016746=IDA, GO:0030324=IEA, GO:0061418=TAS, GO:0005634=IDA, GO:0032092=IEA, GO:0002039=IEA, GO:0005737=IDA, GO:0051091=IDA, GO:0045944=IDA, GO:0033613=IPI, GO:0004402=IDA, GO:0001666=IDA, GO:0005667=IEA, GO:0006355=IDA, GO:0005730=IDA, GO:0006915=IMP, GO:0071456=TAS, GO:0003677=IDA, GO:0006351=IEA, GO:0007399=TAS, GO:0019048=IEA, GO:0003682=IMP} N-terminal peptidyl-lysine acetylation, Notch signaling pathway, apoptotic process, cell cycle, cellular response to hypoxia, cellular response to stress, heart development, histone H4 acetylation, innate immune response, internal peptidyl-lysine acetylation, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, lung development, negative regulation of transcription from RNA polymerase II promoter, nervous system development, organ morphogenesis, positive regulation by host of viral transcription, positive regulation of protein binding, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, regulation of androgen receptor signaling pathway, regulation of transcription from RNA polymerase II promoter in response to hypoxia, regulation of transcription, DNA-dependent, response to estrogen stimulus, response to hypoxia, skeletal muscle tissue development, somitogenesis, transcription, DNA-dependent, virus-host interaction cytoplasm, histone acetyltransferase complex, nucleolus, nucleoplasm, nucleus, transcription factor complex DNA binding, RNA polymerase II activating transcription factor binding, acetyltransferase activity, activating transcription factor binding, androgen receptor binding, beta-catenin binding, chromatin DNA binding, chromatin binding, histone acetyltransferase activity, lysine N-acetyltransferase activity, p53 binding, protein binding, transcription coactivator activity, transcription factor binding, transferase activity, transferring acyl groups, zinc ion binding Human EP400 UniProtKB UniProtKB {GO:0016607=GO_REF:0000024, GO:0043967=PMID:14966270, GO:0043968=PMID:14966270, GO:0003682=GO_REF:0000002, GO:0035267=PMID:14966270, GO:0004386=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000037} Q96L91 E1A-binding protein p400 protein 20100920 {GO:0016607=ISS, GO:0043967=IDA, GO:0043968=IDA, GO:0003682=IEA, GO:0035267=IDA, GO:0004386=IEA, GO:0005524=IEA, GO:0003677=IEA} histone H2A acetylation, histone H4 acetylation NuA4 histone acetyltransferase complex, nuclear speck ATP binding, DNA binding, chromatin binding, helicase activity Human UniProtKB:Q8CHI8 EP400NL null null {} null null null null {} null null null EPAS1 BHF-UCL UniProtKB {GO:0005515=PMID:18000879, GO:0006366=PMID:9079689, GO:0030324=GO_REF:0000019, GO:0061418=Reactome:REACT_120815, GO:0005829=Reactome:REACT_120857, GO:0042415=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0045944=PMID:9576906, GO:0043129=GO_REF:0000019, GO:0048469=GO_REF:0000019, GO:0004871=GO_REF:0000002, GO:0048625=GO_REF:0000024, GO:0035035=PMID:15261140, GO:0005667=PMID:9576906, GO:0001666=PMID:11782478, GO:0046982=PMID:9079689, GO:0071456=Reactome:REACT_121311, GO:0001892=GO_REF:0000019, GO:0033554=Reactome:REACT_120956, GO:0043619=GO_REF:0000019, GO:0001525=GO_REF:0000019, GO:0003677=PMID:9000051, GO:0043565=PMID:9079689, GO:0007165=PMID:9079689, GO:0001077=GO_REF:0000019, GO:0002027=GO_REF:0000019, GO:0001974=GO_REF:0000019, GO:0030218=GO_REF:0000019, GO:0005654=Reactome:REACT_121374, GO:0007005=GO_REF:0000019, GO:0007601=GO_REF:0000019, GO:0008134=PMID:9079689} Q99814 Endothelial PAS domain-containing protein 1 protein 20101221 {GO:0005515=IPI, GO:0006366=TAS, GO:0030324=IEA, GO:0061418=TAS, GO:0005829=TAS, GO:0042415=IEA, GO:0005737=IEA, GO:0045944=IGI, GO:0043129=IEA, GO:0048469=IEA, GO:0004871=IEA, GO:0048625=ISS, GO:0035035=IPI, GO:0005667=IPI, GO:0001666=IDA, GO:0046982=IPI, GO:0071456=TAS, GO:0001892=IEA, GO:0033554=TAS, GO:0043619=IEA, GO:0001525=IEA, GO:0003677=IGI, GO:0043565=IDA, GO:0007165=TAS, GO:0001077=IEA, GO:0002027=IEA, GO:0001974=IEA, GO:0030218=IEA, GO:0005654=TAS, GO:0007005=IEA, GO:0007601=IEA, GO:0008134=IPI} angiogenesis, blood vessel remodeling, cell maturation, cellular response to hypoxia, cellular response to stress, embryonic placenta development, erythrocyte differentiation, lung development, mitochondrion organization, myoblast fate commitment, norepinephrine metabolic process, positive regulation of transcription from RNA polymerase II promoter, regulation of heart rate, regulation of transcription from RNA polymerase II promoter in response to hypoxia, regulation of transcription from RNA polymerase II promoter in response to oxidative stress, response to hypoxia, signal transduction, surfactant homeostasis, transcription from RNA polymerase II promoter, visual perception cytoplasm, cytosol, nucleoplasm, transcription factor complex DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, histone acetyltransferase binding, protein binding, protein heterodimerization activity, sequence-specific DNA binding, signal transducer activity, transcription factor binding Human UniProtKB:P97481 EPB41 HPA UniProtKB {GO:0005515=PMID:8922391, GO:0008091=PMID:6894932, GO:0005516=GO_REF:0000037, GO:0005794=GO_REF:0000052, GO:0030036=PMID:8434260, GO:0005886=GO_REF:0000052, GO:0008015=PMID:6894932, GO:0030507=PMID:3693401, GO:0003779=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0014731=PMID:3693401, GO:0032092=PMID:3693401, GO:0043231=GO_REF:0000052, GO:0043234=PMID:16060676, GO:0005545=PMID:16669616, GO:0005198=GO_REF:0000002, GO:0030866=GO_REF:0000002, GO:0005200=PMID:6894932, GO:0030863=PMID:16254212, GO:0005856=GO_REF:0000002, GO:0019898=GO_REF:0000002} P11171 Protein 4.1 protein 20101115 {GO:0005515=IPI, GO:0008091=TAS, GO:0005516=IEA, GO:0005794=IDA, GO:0030036=NAS, GO:0005886=IDA, GO:0008015=TAS, GO:0030507=TAS, GO:0003779=IEA, GO:0005634=IDA, GO:0014731=TAS, GO:0032092=IDA, GO:0043231=IDA, GO:0043234=IDA, GO:0005545=IDA, GO:0005198=IEA, GO:0030866=IEA, GO:0005200=TAS, GO:0030863=IDA, GO:0005856=IEA, GO:0019898=IEA} actin cytoskeleton organization, blood circulation, cortical actin cytoskeleton organization, positive regulation of protein binding Golgi apparatus, cortical cytoskeleton, cytoskeleton, extrinsic to membrane, intracellular membrane-bounded organelle, nucleus, plasma membrane, protein complex, spectrin, spectrin-associated cytoskeleton 1-phosphatidylinositol binding, actin binding, calmodulin binding, protein binding, spectrin binding, structural constituent of cytoskeleton, structural molecule activity Human EPB41L1 Reactome UniProtKB {GO:0008092=GO_REF:0000002, GO:0005737=GO_REF:0000002, GO:0005886=Reactome:REACT_18393, GO:0030866=GO_REF:0000002, GO:0005198=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0003779=GO_REF:0000037, GO:0005856=GO_REF:0000039, GO:0005829=Reactome:REACT_18393, GO:0019898=GO_REF:0000002} Q9H4G0 Band 4.1-like protein 1 protein 20130301 {GO:0008092=IEA, GO:0005737=IEA, GO:0005886=TAS, GO:0030866=IEA, GO:0005198=IEA, GO:0007268=TAS, GO:0003779=IEA, GO:0005856=IEA, GO:0005829=TAS, GO:0019898=IEA} cortical actin cytoskeleton organization, synaptic transmission cytoplasm, cytoskeleton, cytosol, extrinsic to membrane, plasma membrane actin binding, cytoskeletal protein binding, structural molecule activity Human EPB41L2 InterPro UniProtKB {GO:0008092=GO_REF:0000002, GO:0008091=PMID:9598318, GO:0030054=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0003779=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0005737=GO_REF:0000002, GO:0008180=PMID:18850735, GO:0005198=GO_REF:0000002, GO:0030866=GO_REF:0000002, GO:0005856=GO_REF:0000002, GO:0042731=GO_REF:0000019, GO:0019898=GO_REF:0000002} Q6ZSX4 Band 4.1-like protein 2 protein 20130413 {GO:0008092=IEA, GO:0008091=TAS, GO:0030054=IDA, GO:0005886=IDA, GO:0005730=IDA, GO:0003779=IEA, GO:0005634=IDA, GO:0005737=IEA, GO:0008180=IDA, GO:0005198=IEA, GO:0030866=IEA, GO:0005856=IEA, GO:0042731=IEA, GO:0019898=IEA} cortical actin cytoskeleton organization cell junction, cytoplasm, cytoskeleton, extrinsic to membrane, nucleolus, nucleus, plasma membrane, signalosome, spectrin PH domain binding, actin binding, cytoskeletal protein binding, structural molecule activity Human InterPro:IPR007477 EPB41L3 BHF-UCL UniProtKB {GO:0005515=PMID:12234973, GO:0005886=PMID:9892180, GO:0030913=GO_REF:0000024, GO:0044224=GO_REF:0000024, GO:0033270=GO_REF:0000024, GO:0003779=GO_REF:0000037, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000037, GO:0005198=GO_REF:0000002, GO:0030866=GO_REF:0000002, GO:0005911=PMID:12234973, GO:0048812=GO_REF:0000024, GO:0043217=GO_REF:0000024, GO:0030673=GO_REF:0000024, GO:0005856=GO_REF:0000039, GO:0019898=GO_REF:0000002} Q9Y2J2 Band 4.1-like protein 3 protein 20130111 {GO:0005515=IPI, GO:0005886=NAS, GO:0030913=ISS, GO:0044224=ISS, GO:0033270=ISS, GO:0003779=IEA, GO:0008150=ND, GO:0005737=IEA, GO:0005198=IEA, GO:0030866=IEA, GO:0005911=IDA, GO:0048812=ISS, GO:0043217=ISS, GO:0030673=ISS, GO:0005856=IEA, GO:0019898=IEA} biological_process, cortical actin cytoskeleton organization, myelin maintenance, neuron projection morphogenesis, paranodal junction assembly axolemma, cell-cell junction, cytoplasm, cytoskeleton, extrinsic to membrane, juxtaparanode region of axon, paranode region of axon, plasma membrane actin binding, protein binding, structural molecule activity Human UniProtKB:Q9WV92 EPB41L4A UniProtKB UniProtKB {GO:0008092=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000037, GO:0005575=GO_REF:0000015, GO:0005856=GO_REF:0000039, GO:0019898=GO_REF:0000002} Q9HCS5 Band 4.1-like protein 4A protein 20061026 {GO:0008092=IEA, GO:0003674=ND, GO:0008150=ND, GO:0005737=IEA, GO:0005575=ND, GO:0005856=IEA, GO:0019898=IEA} biological_process cellular_component, cytoplasm, cytoskeleton, extrinsic to membrane cytoskeletal protein binding, molecular_function Human EPB41L4B MGI UniProtKB {GO:0008092=GO_REF:0000002, GO:0005737=GO_REF:0000037, GO:0005200=PMID:10783258, GO:0045177=PMID:22006950, GO:0031032=PMID:22006950, GO:0005856=GO_REF:0000039, GO:0019898=GO_REF:0000002} Q9H329 Band 4.1-like protein 4B protein 20120406 {GO:0008092=IEA, GO:0005737=IEA, GO:0005200=TAS, GO:0045177=IDA, GO:0031032=IDA, GO:0005856=IEA, GO:0019898=IEA} actomyosin structure organization apical part of cell, cytoplasm, cytoskeleton, extrinsic to membrane cytoskeletal protein binding, structural constituent of cytoskeleton Human EPB41L5 UniProtKB UniProtKB {GO:0008092=GO_REF:0000002, GO:0032091=GO_REF:0000019, GO:0010718=GO_REF:0000019, GO:0071560=GO_REF:0000019, GO:0001839=GO_REF:0000019, GO:0031032=GO_REF:0000019, GO:0070986=GO_REF:0000019, GO:0001837=GO_REF:0000019, GO:0051894=GO_REF:0000019, GO:0032092=GO_REF:0000019, GO:0006931=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0032525=GO_REF:0000019, GO:0007509=GO_REF:0000019, GO:0070201=GO_REF:0000019, GO:0005856=GO_REF:0000002, GO:0048319=GO_REF:0000019, GO:0003383=GO_REF:0000019, GO:0022408=GO_REF:0000019, GO:0048339=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0032587=GO_REF:0000019, GO:0007398=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0009826=GO_REF:0000019, GO:0010608=GO_REF:0000019, GO:0007492=GO_REF:0000019, GO:0048617=GO_REF:0000019, GO:0010634=GO_REF:0000019, GO:0005925=GO_REF:0000019, GO:0019898=GO_REF:0000002} Q9HCM4 Band 4.1-like protein 5 protein 20130413 {GO:0008092=IEA, GO:0032091=IEA, GO:0010718=IEA, GO:0071560=IEA, GO:0001839=IEA, GO:0031032=IEA, GO:0070986=IEA, GO:0001837=IEA, GO:0051894=IEA, GO:0032092=IEA, GO:0006931=IEA, GO:0005737=IEA, GO:0032525=IEA, GO:0007509=IEA, GO:0070201=IEA, GO:0005856=IEA, GO:0048319=IEA, GO:0003383=IEA, GO:0022408=IEA, GO:0048339=IEA, GO:0019904=IEA, GO:0032587=IEA, GO:0007398=IEA, GO:0001701=IEA, GO:0009826=IEA, GO:0010608=IEA, GO:0007492=IEA, GO:0048617=IEA, GO:0010634=IEA, GO:0005925=IEA, GO:0019898=IEA} actomyosin structure organization, apical constriction, axial mesoderm morphogenesis, cellular response to transforming growth factor beta stimulus, ectoderm development, embryonic foregut morphogenesis, endoderm development, epithelial to mesenchymal transition, in utero embryonic development, left/right axis specification, mesoderm migration involved in gastrulation, negative regulation of cell-cell adhesion, negative regulation of protein binding, neural plate morphogenesis, paraxial mesoderm development, positive regulation of epithelial cell migration, positive regulation of epithelial to mesenchymal transition, positive regulation of focal adhesion assembly, positive regulation of protein binding, posttranscriptional regulation of gene expression, regulation of establishment of protein localization, somite rostral/caudal axis specification, substrate-dependent cell migration, cell attachment to substrate, unidimensional cell growth cytoplasm, cytoskeleton, extrinsic to membrane, focal adhesion, ruffle membrane cytoskeletal protein binding, protein domain specific binding Human UniProtKB-SubCell:SL-0086 EPB42 IntAct UniProtKB {GO:0005515=PMID:12970870, GO:0020027=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0008360=GO_REF:0000037, GO:0048536=GO_REF:0000019, GO:0055072=GO_REF:0000019, GO:0005524=PMID:8608138, GO:0000902=GO_REF:0000019, GO:0018149=GO_REF:0000002, GO:0043249=GO_REF:0000037, GO:0003810=GO_REF:0000002, GO:0005200=PMID:1350227, GO:0030863=GO_REF:0000019, GO:0005856=PMID:1350227} P16452 Erythrocyte membrane protein band 4.2 protein 20130415 {GO:0005515=IPI, GO:0020027=IEA, GO:0005886=IEA, GO:0008360=IEA, GO:0048536=IEA, GO:0055072=IEA, GO:0005524=TAS, GO:0000902=IEA, GO:0018149=IEA, GO:0043249=IEA, GO:0003810=IEA, GO:0005200=TAS, GO:0030863=IEA, GO:0005856=TAS} cell morphogenesis, erythrocyte maturation, hemoglobin metabolic process, iron ion homeostasis, peptide cross-linking, regulation of cell shape, spleen development cortical cytoskeleton, cytoskeleton, plasma membrane ATP binding, protein binding, protein-glutamine gamma-glutamyltransferase activity, structural constituent of cytoskeleton Human UniProtKB:P58062 EPB49 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0016020=GO_REF:0000019, GO:0007010=PMID:7615546, GO:0030863=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0003779=GO_REF:0000037, GO:0015629=PMID:8341682, GO:0051017=PMID:7615546, GO:0051693=GO_REF:0000037} Q08495 Dematin protein 20101115 {GO:0005737=IDA, GO:0016020=IEA, GO:0007010=TAS, GO:0030863=IEA, GO:0005634=IDA, GO:0003779=IEA, GO:0015629=TAS, GO:0051017=TAS, GO:0051693=IEA} actin filament bundle assembly, actin filament capping, cytoskeleton organization actin cytoskeleton, cortical cytoskeleton, cytoplasm, membrane, nucleus actin binding Human EPC1 MGI UniProtKB {GO:0031965=PMID:10976108, GO:0005634=PMID:17192267, GO:0000122=PMID:10976108, GO:0006351=PMID:10976108, GO:0032777=PMID:14966270, GO:0043967=PMID:14966270, GO:0045944=PMID:10976108, GO:0045814=PMID:10976108, GO:0043968=PMID:14966270, GO:0035267=PMID:14966270, GO:0005654=PMID:10976108, GO:0045893=PMID:10976108, GO:0045892=PMID:10976108, GO:0040008=GO_REF:0000037, GO:0004402=PMID:14966270} Q9H2F5 Enhancer of polycomb homolog 1 protein 20070611 {GO:0031965=IDA, GO:0005634=IDA, GO:0000122=IDA, GO:0006351=TAS, GO:0032777=IDA, GO:0043967=IDA, GO:0045944=IDA, GO:0045814=IDA, GO:0043968=IDA, GO:0035267=IDA, GO:0005654=IDA, GO:0045893=TAS, GO:0045892=IDA, GO:0040008=IEA, GO:0004402=IDA} histone H2A acetylation, histone H4 acetylation, negative regulation of gene expression, epigenetic, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of growth, transcription, DNA-dependent NuA4 histone acetyltransferase complex, Piccolo NuA4 histone acetyltransferase complex, nuclear membrane, nucleoplasm, nucleus histone acetyltransferase activity Human EPC2 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0006281=GO_REF:0000037, GO:0032777=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q52LR7 Enhancer of polycomb homolog 2 protein 20130413 {GO:0006355=IEA, GO:0006281=IEA, GO:0032777=IEA, GO:0006351=IEA, GO:0016568=IEA} DNA repair, chromatin modification, regulation of transcription, DNA-dependent, transcription, DNA-dependent Piccolo NuA4 histone acetyltransferase complex Human UniProtKB-KW:KW-0156 EPCAM MGI UniProtKB {GO:0005515=PMID:16054130, GO:0016323=PMID:18025791, GO:0001657=GO_REF:0000019, GO:0016324=PMID:18025791, GO:0008284=PMID:15195135, GO:0005886=PMID:19785009, GO:0009986=GO_REF:0000019, GO:0005923=PMID:16054130, GO:0016021=GO_REF:0000019, GO:0016328=PMID:16054130} P16422 Epithelial cell adhesion molecule protein 20090324 {GO:0005515=IPI, GO:0016323=IDA, GO:0001657=IEA, GO:0016324=IDA, GO:0008284=IDA, GO:0005886=IDA, GO:0009986=IEA, GO:0005923=IDA, GO:0016021=IEA, GO:0016328=IDA} positive regulation of cell proliferation, ureteric bud development apical plasma membrane, basolateral plasma membrane, cell surface, integral to membrane, lateral plasma membrane, plasma membrane, tight junction protein binding Human EPDR1 UniProtKB UniProtKB {GO:0007160=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0005764=GO_REF:0000019} Q9UM22 Mammalian ependymin-related protein 1 protein 20130413 {GO:0007160=IEA, GO:0005509=IEA, GO:0005576=IEA, GO:0005764=IEA} cell-matrix adhesion extracellular region, lysosome calcium ion binding Human UniProtKB-SubCell:SL-0243 EPG5 UniProtKB UniProtKB {GO:0006914=GO_REF:0000037} Q9HCE0 Ectopic P granules protein 5 homolog protein 20130413 {GO:0006914=IEA} autophagy Human UniProtKB-KW:KW-0072 EPHA1 UniProtKB UniProtKB {GO:0008284=PMID:20043122, GO:0030336=PMID:19118217, GO:0030335=PMID:20043122, GO:0019901=PMID:19118217, GO:0001525=GO_REF:0000037, GO:0032862=PMID:19118217, GO:0005524=GO_REF:0000037, GO:0045766=PMID:20043122, GO:0005005=PMID:19118217, GO:0004672=PMID:12775584, GO:0046777=PMID:19118217, GO:0032314=PMID:19118217, GO:0005887=PMID:19118217, GO:0051496=GO_REF:0000024, GO:0034446=PMID:19118217, GO:0006469=PMID:19118217, GO:0001954=PMID:19118217, GO:0007166=PMID:19118217} P21709 Ephrin type-A receptor 1 protein 20110923 {GO:0008284=IMP, GO:0030336=IDA, GO:0030335=IMP, GO:0019901=IPI, GO:0001525=IEA, GO:0032862=IDA, GO:0005524=IEA, GO:0045766=IMP, GO:0005005=IDA, GO:0004672=IDA, GO:0046777=IDA, GO:0032314=IDA, GO:0005887=IDA, GO:0051496=ISS, GO:0034446=IDA, GO:0006469=IDA, GO:0001954=IDA, GO:0007166=IDA} activation of Rho GTPase activity, angiogenesis, cell surface receptor signaling pathway, negative regulation of cell migration, negative regulation of protein kinase activity, positive regulation of angiogenesis, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of cell-matrix adhesion, positive regulation of stress fiber assembly, protein autophosphorylation, regulation of Rac GTPase activity, substrate adhesion-dependent cell spreading integral to plasma membrane ATP binding, protein kinase activity, protein kinase binding, transmembrane-ephrin receptor activity Human UniProtKB:Q60750 EPHA2 IntAct UniProtKB {GO:0051898=PMID:19573808, GO:0005515=PMID:22939624, GO:0033628=PMID:10655584, GO:0005886=PMID:20861311, GO:0014028=GO_REF:0000019, GO:0010591=PMID:19573808, GO:0005003=GO_REF:0000002, GO:0046849=GO_REF:0000024, GO:0030182=GO_REF:0000019, GO:0070309=GO_REF:0000024, GO:0007155=GO_REF:0000037, GO:0070372=PMID:20861311, GO:0060035=GO_REF:0000019, GO:0031256=PMID:19573808, GO:0031258=GO_REF:0000039, GO:0048013=PMID:10655584, GO:0030316=GO_REF:0000024, GO:0045765=GO_REF:0000024, GO:0006915=PMID:18339848, GO:0007275=PMID:7918100, GO:0032587=GO_REF:0000039, GO:0001525=GO_REF:0000037, GO:0070848=PMID:19573808, GO:0032863=PMID:20679435, GO:0005524=GO_REF:0000037, GO:0001649=GO_REF:0000024, GO:0036342=GO_REF:0000019, GO:0043535=GO_REF:0000024, GO:0033598=GO_REF:0000024, GO:0001501=GO_REF:0000019, GO:0005887=PMID:10655584, GO:0060326=PMID:19573808, GO:0030216=PMID:20861311, GO:0043491=PMID:19573808, GO:0021915=GO_REF:0000019, GO:0004714=PMID:10655584, GO:0005925=PMID:10655584, GO:0001570=GO_REF:0000019, GO:0060444=GO_REF:0000024, GO:0048320=GO_REF:0000019, GO:0090004=PMID:20679435} P29317 Ephrin type-A receptor 2 protein 20130415 {GO:0051898=IDA, GO:0005515=IPI, GO:0033628=IDA, GO:0005886=IDA, GO:0014028=IEA, GO:0010591=IMP, GO:0005003=IEA, GO:0046849=ISS, GO:0030182=IEA, GO:0070309=ISS, GO:0007155=IEA, GO:0070372=IMP, GO:0060035=IEA, GO:0031256=IDA, GO:0031258=IEA, GO:0048013=IDA, GO:0030316=ISS, GO:0045765=ISS, GO:0006915=IDA, GO:0007275=TAS, GO:0032587=IEA, GO:0001525=IEA, GO:0070848=IMP, GO:0032863=IMP, GO:0005524=IEA, GO:0001649=ISS, GO:0036342=IEA, GO:0043535=ISS, GO:0033598=ISS, GO:0001501=IEA, GO:0005887=IDA, GO:0060326=IMP, GO:0030216=IMP, GO:0043491=IDA, GO:0021915=IEA, GO:0004714=IDA, GO:0005925=IDA, GO:0001570=IEA, GO:0060444=ISS, GO:0048320=IEA, GO:0090004=IMP} activation of Rac GTPase activity, angiogenesis, apoptotic process, axial mesoderm formation, bone remodeling, branching involved in mammary gland duct morphogenesis, cell adhesion, cell chemotaxis, ephrin receptor signaling pathway, keratinocyte differentiation, lens fiber cell morphogenesis, mammary gland epithelial cell proliferation, multicellular organismal development, negative regulation of protein kinase B signaling cascade, neural tube development, neuron differentiation, notochord cell development, notochord formation, osteoblast differentiation, osteoclast differentiation, positive regulation of establishment of protein localization to plasma membrane, post-anal tail morphogenesis, protein kinase B signaling cascade, regulation of ERK1 and ERK2 cascade, regulation of angiogenesis, regulation of blood vessel endothelial cell migration, regulation of cell adhesion mediated by integrin, regulation of lamellipodium assembly, response to growth factor stimulus, skeletal system development, vasculogenesis focal adhesion, integral to plasma membrane, lamellipodium membrane, leading edge membrane, plasma membrane, ruffle membrane ATP binding, ephrin receptor activity, protein binding, transmembrane receptor protein tyrosine kinase activity Human UniProtKB:P08238 EPHA3 BHF-UCL UniProtKB {GO:0005515=PMID:21135139, GO:0048013=PMID:11870224, GO:0071300=PMID:17910947, GO:0006915=GO_REF:0000024, GO:0010717=GO_REF:0000024, GO:0005576=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0051893=PMID:11870224, GO:0070507=PMID:11870224, GO:0005004=PMID:11870224, GO:0005003=GO_REF:0000002, GO:0016477=GO_REF:0000024, GO:0005887=PMID:11870224, GO:0032956=PMID:11870224, GO:0010976=PMID:17910947, GO:0032319=PMID:11870224, GO:0007155=GO_REF:0000037, GO:0097156=GO_REF:0000024, GO:0097155=GO_REF:0000024, GO:0005769=PMID:21135139} P29320 Ephrin type-A receptor 3 protein 20110707 {GO:0005515=IPI, GO:0048013=IDA, GO:0071300=IMP, GO:0006915=ISS, GO:0010717=ISS, GO:0005576=IEA, GO:0005524=IEA, GO:0051893=IDA, GO:0070507=IDA, GO:0005004=IDA, GO:0005003=IEA, GO:0016477=ISS, GO:0005887=IDA, GO:0032956=IDA, GO:0010976=IMP, GO:0032319=IDA, GO:0007155=IEA, GO:0097156=ISS, GO:0097155=ISS, GO:0005769=IDA} apoptotic process, cell adhesion, cell migration, cellular response to retinoic acid, ephrin receptor signaling pathway, fasciculation of motor neuron axon, fasciculation of sensory neuron axon, positive regulation of neuron projection development, regulation of Rho GTPase activity, regulation of actin cytoskeleton organization, regulation of epithelial to mesenchymal transition, regulation of focal adhesion assembly, regulation of microtubule cytoskeleton organization early endosome, extracellular region, integral to plasma membrane ATP binding, GPI-linked ephrin receptor activity, ephrin receptor activity, protein binding Human EPHA4 UniProtKB UniProtKB {GO:0005515=PMID:12775584, GO:0030424=GO_REF:0000024, GO:0097161=PMID:12775584, GO:0030054=GO_REF:0000037, GO:0031594=GO_REF:0000019, GO:0008347=GO_REF:0000019, GO:0005783=GO_REF:0000019, GO:0005741=GO_REF:0000019, GO:0030175=GO_REF:0000019, GO:0030425=GO_REF:0000024, GO:0005005=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0005004=GO_REF:0000024, GO:0005003=GO_REF:0000002, GO:0032314=GO_REF:0000024, GO:0048681=GO_REF:0000024, GO:0045211=GO_REF:0000037, GO:0007628=GO_REF:0000019, GO:0043204=GO_REF:0000019, GO:0043679=GO_REF:0000019, GO:0043507=GO_REF:0000019, GO:0007155=GO_REF:0000037, GO:0061001=GO_REF:0000024, GO:0097156=GO_REF:0000024, GO:0097155=GO_REF:0000024, GO:0032317=GO_REF:0000024, GO:0005794=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0021957=GO_REF:0000024, GO:2001108=PMID:12775584, GO:0014069=GO_REF:0000039, GO:0044295=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0048710=GO_REF:0000024, GO:0008045=GO_REF:0000024, GO:0004672=PMID:12775584, GO:0046875=GO_REF:0000019, GO:0005887=GO_REF:0000024, GO:0050775=GO_REF:0000019, GO:0031901=GO_REF:0000024, GO:0042731=PMID:12775584, GO:0050770=GO_REF:0000024} P54764 Ephrin type-A receptor 4 protein 20110819 {GO:0005515=IPI, GO:0030424=ISS, GO:0097161=IDA, GO:0030054=IEA, GO:0031594=IEA, GO:0008347=IEA, GO:0005783=IEA, GO:0005741=IEA, GO:0030175=IEA, GO:0030425=ISS, GO:0005005=ISS, GO:0005737=ISS, GO:0005004=ISS, GO:0005003=IEA, GO:0032314=ISS, GO:0048681=ISS, GO:0045211=IEA, GO:0007628=IEA, GO:0043204=IEA, GO:0043679=IEA, GO:0043507=IEA, GO:0007155=IEA, GO:0061001=ISS, GO:0097156=ISS, GO:0097155=ISS, GO:0032317=ISS, GO:0005794=IEA, GO:0009986=IEA, GO:0021957=ISS, GO:2001108=IDA, GO:0014069=IEA, GO:0044295=IEA, GO:0005524=IEA, GO:0048710=ISS, GO:0008045=ISS, GO:0004672=IDA, GO:0046875=IEA, GO:0005887=ISS, GO:0050775=IEA, GO:0031901=ISS, GO:0042731=IPI, GO:0050770=ISS} adult walking behavior, cell adhesion, corticospinal tract morphogenesis, fasciculation of motor neuron axon, fasciculation of sensory neuron axon, glial cell migration, motor neuron axon guidance, negative regulation of axon regeneration, positive regulation of JUN kinase activity, positive regulation of Rho guanyl-nucleotide exchange factor activity, positive regulation of dendrite morphogenesis, regulation of Rac GTPase activity, regulation of Rap GTPase activity, regulation of astrocyte differentiation, regulation of axonogenesis, regulation of dendritic spine morphogenesis Golgi apparatus, axon, axon terminus, axonal growth cone, cell junction, cell surface, cytoplasm, dendrite, early endosome membrane, endoplasmic reticulum, filopodium, integral to plasma membrane, mitochondrial outer membrane, neuromuscular junction, perikaryon, postsynaptic density, postsynaptic membrane ATP binding, DH domain binding, GPI-linked ephrin receptor activity, PH domain binding, ephrin receptor activity, ephrin receptor binding, protein binding, protein kinase activity, transmembrane-ephrin receptor activity Human UniProtKB:Q03137 EPHA5 UniProtKB UniProtKB {GO:0005791=PMID:10375373, GO:0030424=GO_REF:0000039, GO:0048471=PMID:10375373, GO:0051964=GO_REF:0000019, GO:0048013=GO_REF:0000024, GO:0005886=PMID:10375373, GO:0005524=GO_REF:0000037, GO:0030425=PMID:10375373, GO:0032793=GO_REF:0000024, GO:0021766=GO_REF:0000024, GO:0005005=PMID:7898931, GO:0005004=GO_REF:0000024, GO:0032314=GO_REF:0000024, GO:0005003=GO_REF:0000024, GO:0048666=PMID:10375373, GO:0007411=GO_REF:0000024, GO:0005887=GO_REF:0000002, GO:0032956=GO_REF:0000024, GO:0019933=GO_REF:0000024, GO:0043025=PMID:10375373, GO:0016021=GO_REF:0000038, GO:0061178=GO_REF:0000024, GO:0009897=PMID:10064801} P54756 Ephrin type-A receptor 5 protein 20110823 {GO:0005791=IDA, GO:0030424=IEA, GO:0048471=IDA, GO:0051964=IEA, GO:0048013=ISS, GO:0005886=IDA, GO:0005524=IEA, GO:0030425=IDA, GO:0032793=ISS, GO:0021766=ISS, GO:0005005=NAS, GO:0005004=ISS, GO:0032314=ISS, GO:0005003=ISS, GO:0048666=IEP, GO:0007411=ISS, GO:0005887=IEA, GO:0032956=ISS, GO:0019933=ISS, GO:0043025=IDA, GO:0016021=IEA, GO:0061178=ISS, GO:0009897=IDA} axon guidance, cAMP-mediated signaling, ephrin receptor signaling pathway, hippocampus development, negative regulation of synapse assembly, neuron development, positive regulation of CREB transcription factor activity, regulation of Rac GTPase activity, regulation of actin cytoskeleton organization, regulation of insulin secretion involved in cellular response to glucose stimulus axon, dendrite, external side of plasma membrane, integral to membrane, integral to plasma membrane, neuronal cell body, perinuclear region of cytoplasm, plasma membrane, rough endoplasmic reticulum ATP binding, GPI-linked ephrin receptor activity, ephrin receptor activity, transmembrane-ephrin receptor activity Human UniProtKB:Q60629 EPHA6 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005003=GO_REF:0000002, GO:0004672=GO_REF:0000002, GO:0005887=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000002, GO:0004713=GO_REF:0000038, GO:0005524=GO_REF:0000037} Q9UF33 Ephrin type-A receptor 6 protein 20110107 {GO:0003674=ND, GO:0008150=ND, GO:0005003=IEA, GO:0004672=IEA, GO:0005887=IEA, GO:0005575=ND, GO:0016021=IEA, GO:0004713=IEA, GO:0005524=IEA} biological_process cellular_component, integral to membrane, integral to plasma membrane ATP binding, ephrin receptor activity, molecular_function, protein kinase activity, protein tyrosine kinase activity Human EPHA7 IntAct UniProtKB {GO:0005515=PMID:22036564, GO:0031290=GO_REF:0000019, GO:0022407=GO_REF:0000024, GO:0031594=GO_REF:0000019, GO:0048013=PMID:17726105, GO:0050730=PMID:17726105, GO:0050919=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0030425=GO_REF:0000019, GO:0031952=GO_REF:0000024, GO:0016310=GO_REF:0000024, GO:0045499=GO_REF:0000024, GO:0005004=GO_REF:0000024, GO:0043281=GO_REF:0000024, GO:0043525=GO_REF:0000024, GO:0046875=GO_REF:0000019, GO:0007420=GO_REF:0000024, GO:0005887=GO_REF:0000002, GO:0045211=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0048755=GO_REF:0000024, GO:0004713=GO_REF:0000024, GO:0008046=GO_REF:0000024, GO:0070372=PMID:17726105} Q15375 Ephrin type-A receptor 7 protein 20130415 {GO:0005515=IPI, GO:0031290=IEA, GO:0022407=ISS, GO:0031594=IEA, GO:0048013=IDA, GO:0050730=IDA, GO:0050919=ISS, GO:0005524=IEA, GO:0030425=IEA, GO:0031952=ISS, GO:0016310=ISS, GO:0045499=ISS, GO:0005004=ISS, GO:0043281=ISS, GO:0043525=ISS, GO:0046875=IEA, GO:0007420=ISS, GO:0005887=IEA, GO:0045211=IEA, GO:0043025=IEA, GO:0048755=ISS, GO:0004713=ISS, GO:0008046=ISS, GO:0070372=IDA} brain development, branching morphogenesis of a nerve, ephrin receptor signaling pathway, negative chemotaxis, phosphorylation, positive regulation of neuron apoptotic process, regulation of ERK1 and ERK2 cascade, regulation of cell-cell adhesion, regulation of cysteine-type endopeptidase activity involved in apoptotic process, regulation of peptidyl-tyrosine phosphorylation, regulation of protein autophosphorylation, retinal ganglion cell axon guidance dendrite, integral to plasma membrane, neuromuscular junction, neuronal cell body, postsynaptic membrane ATP binding, GPI-linked ephrin receptor activity, axon guidance receptor activity, chemorepellent activity, ephrin receptor binding, protein binding, protein tyrosine kinase activity Human UniProtKB:P52793 EPHA8 UniProtKB UniProtKB {GO:0043005=GO_REF:0000024, GO:0033628=GO_REF:0000024, GO:0048013=GO_REF:0000024, GO:0006929=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0030155=GO_REF:0000024, GO:0031175=GO_REF:0000024, GO:0016322=GO_REF:0000024, GO:0005004=GO_REF:0000024, GO:0046777=GO_REF:0000024, GO:0043552=GO_REF:0000024, GO:0005887=GO_REF:0000024, GO:0007411=GO_REF:0000024, GO:0031901=GO_REF:0000039, GO:0007155=GO_REF:0000037, GO:0043410=GO_REF:0000024} P29322 Ephrin type-A receptor 8 protein 20110830 {GO:0043005=ISS, GO:0033628=ISS, GO:0048013=ISS, GO:0006929=ISS, GO:0005524=IEA, GO:0030155=ISS, GO:0031175=ISS, GO:0016322=ISS, GO:0005004=ISS, GO:0046777=ISS, GO:0043552=ISS, GO:0005887=ISS, GO:0007411=ISS, GO:0031901=IEA, GO:0007155=IEA, GO:0043410=ISS} axon guidance, cell adhesion, ephrin receptor signaling pathway, neuron projection development, neuron remodeling, positive regulation of MAPK cascade, positive regulation of phosphatidylinositol 3-kinase activity, protein autophosphorylation, regulation of cell adhesion, regulation of cell adhesion mediated by integrin, substrate-dependent cell migration early endosome membrane, integral to plasma membrane, neuron projection ATP binding, GPI-linked ephrin receptor activity Human UniProtKB:O09127 EPHB1 IntAct UniProtKB {GO:0031290=GO_REF:0000024, GO:0005515=PMID:12223469, GO:0030424=GO_REF:0000019, GO:0030010=GO_REF:0000024, GO:0048593=GO_REF:0000019, GO:0030425=GO_REF:0000039, GO:0046328=PMID:9430661, GO:0061351=GO_REF:0000024, GO:0005005=PMID:18034775, GO:0005737=GO_REF:0000019, GO:0046777=PMID:18034775, GO:0005003=GO_REF:0000002, GO:0007411=GO_REF:0000024, GO:0060996=GO_REF:0000024, GO:0060997=GO_REF:0000024, GO:0070372=PMID:12925710, GO:0050965=GO_REF:0000024, GO:0022008=GO_REF:0000024, GO:0051965=GO_REF:0000024, GO:0048013=PMID:12925710, GO:0031589=PMID:9430661, GO:0021952=GO_REF:0000024, GO:0001525=PMID:9499402, GO:0005524=GO_REF:0000037, GO:0060326=PMID:12925710, GO:0005887=PMID:18034775, GO:0031901=PMID:18034775, GO:0045121=GO_REF:0000019, GO:0004713=GO_REF:0000019, GO:0016021=GO_REF:0000002, GO:0021631=GO_REF:0000019, GO:0008046=GO_REF:0000019} P54762 Ephrin type-B receptor 1 protein 20130415 {GO:0031290=ISS, GO:0005515=IPI, GO:0030424=IEA, GO:0030010=ISS, GO:0048593=IEA, GO:0030425=IEA, GO:0046328=IDA, GO:0061351=ISS, GO:0005005=IDA, GO:0005737=IEA, GO:0046777=IDA, GO:0005003=IEA, GO:0007411=ISS, GO:0060996=ISS, GO:0060997=ISS, GO:0070372=IDA, GO:0050965=ISS, GO:0022008=ISS, GO:0051965=ISS, GO:0048013=IDA, GO:0031589=IDA, GO:0021952=ISS, GO:0001525=IDA, GO:0005524=IEA, GO:0060326=IDA, GO:0005887=IDA, GO:0031901=IDA, GO:0045121=IEA, GO:0004713=IEA, GO:0016021=IEA, GO:0021631=IEA, GO:0008046=IEA} angiogenesis, axon guidance, camera-type eye morphogenesis, cell chemotaxis, cell-substrate adhesion, central nervous system projection neuron axonogenesis, dendritic spine development, dendritic spine morphogenesis, detection of temperature stimulus involved in sensory perception of pain, ephrin receptor signaling pathway, establishment of cell polarity, neural precursor cell proliferation, neurogenesis, optic nerve morphogenesis, positive regulation of synapse assembly, protein autophosphorylation, regulation of ERK1 and ERK2 cascade, regulation of JNK cascade, retinal ganglion cell axon guidance axon, cytoplasm, dendrite, early endosome membrane, integral to membrane, integral to plasma membrane, membrane raft ATP binding, axon guidance receptor activity, ephrin receptor activity, protein binding, protein tyrosine kinase activity, transmembrane-ephrin receptor activity Human UniProtKB:Q14451 EPHB2 InterPro UniProtKB {GO:0031290=GO_REF:0000019, GO:0030424=GO_REF:0000024, GO:0071679=GO_REF:0000024, GO:0001655=GO_REF:0000024, GO:0048593=GO_REF:0000019, GO:0030425=GO_REF:0000024, GO:0005005=GO_REF:0000024, GO:0005003=GO_REF:0000002, GO:0007413=GO_REF:0000024, GO:0007411=Reactome:REACT_18266, GO:0043025=GO_REF:0000019, GO:0060021=GO_REF:0000024, GO:0060996=GO_REF:0000024, GO:0007612=GO_REF:0000019, GO:0060997=GO_REF:0000024, GO:0051965=GO_REF:0000024, GO:0042472=GO_REF:0000024, GO:0048013=GO_REF:0000024, GO:0005102=GO_REF:0000019, GO:0021952=GO_REF:0000019, GO:0018108=GO_REF:0000024, GO:0001525=GO_REF:0000024, GO:0005524=GO_REF:0000002, GO:0007399=PMID:8589679, GO:0022038=GO_REF:0000024, GO:0016310=GO_REF:0000024, GO:0005887=GO_REF:0000024, GO:0050771=GO_REF:0000019, GO:0006468=GO_REF:0000029, GO:0016021=GO_REF:0000002, GO:0004713=GO_REF:0000024, GO:0021631=GO_REF:0000019, GO:0008046=GO_REF:0000019, GO:0050878=GO_REF:0000024, GO:0048170=GO_REF:0000019} Q6NVW1 EPHB2 protein protein 20130413 {GO:0031290=IEA, GO:0030424=ISS, GO:0071679=ISS, GO:0001655=ISS, GO:0048593=IEA, GO:0030425=ISS, GO:0005005=ISS, GO:0005003=IEA, GO:0007413=ISS, GO:0007411=TAS, GO:0043025=IEA, GO:0060021=ISS, GO:0060996=ISS, GO:0007612=IEA, GO:0060997=ISS, GO:0051965=ISS, GO:0042472=ISS, GO:0048013=ISS, GO:0005102=IEA, GO:0021952=IEA, GO:0018108=ISS, GO:0001525=ISS, GO:0005524=IEA, GO:0007399=TAS, GO:0022038=ISS, GO:0016310=ISS, GO:0005887=ISS, GO:0050771=IEA, GO:0006468=TAS, GO:0016021=IEA, GO:0004713=ISS, GO:0021631=IEA, GO:0008046=IEA, GO:0050878=ISS, GO:0048170=IEA} angiogenesis, axon guidance, axonal fasciculation, camera-type eye morphogenesis, central nervous system projection neuron axonogenesis, commissural neuron axon guidance, corpus callosum development, dendritic spine development, dendritic spine morphogenesis, ephrin receptor signaling pathway, inner ear morphogenesis, learning, negative regulation of axonogenesis, nervous system development, optic nerve morphogenesis, palate development, peptidyl-tyrosine phosphorylation, phosphorylation, positive regulation of long-term neuronal synaptic plasticity, positive regulation of synapse assembly, protein phosphorylation, regulation of body fluid levels, retinal ganglion cell axon guidance, urogenital system development axon, dendrite, integral to membrane, integral to plasma membrane, neuronal cell body ATP binding, axon guidance receptor activity, ephrin receptor activity, protein tyrosine kinase activity, receptor binding, transmembrane-ephrin receptor activity Human InterPro:IPR001426 EPHB3 UniProtKB UniProtKB {GO:0031290=GO_REF:0000019, GO:0001655=GO_REF:0000024, GO:0048538=GO_REF:0000024, GO:0030425=GO_REF:0000039, GO:0007413=GO_REF:0000024, GO:0005003=PMID:15536074, GO:0046777=PMID:15536074, GO:0032314=PMID:15536074, GO:0007411=GO_REF:0000024, GO:0034446=PMID:15536074, GO:0060021=GO_REF:0000024, GO:0060996=GO_REF:0000024, GO:0060997=GO_REF:0000024, GO:0051965=GO_REF:0000024, GO:0022407=PMID:8397371, GO:0048013=PMID:15536074, GO:0021952=GO_REF:0000019, GO:0001525=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0048546=GO_REF:0000024, GO:0043088=PMID:15536074, GO:0022038=GO_REF:0000024, GO:0016477=PMID:15536074, GO:0005887=PMID:15536074, GO:0008046=GO_REF:0000019, GO:0050770=GO_REF:0000024} P54753 Ephrin type-B receptor 3 protein 20110906 {GO:0031290=IEA, GO:0001655=ISS, GO:0048538=ISS, GO:0030425=IEA, GO:0007413=ISS, GO:0005003=IDA, GO:0046777=IDA, GO:0032314=IDA, GO:0007411=ISS, GO:0034446=IDA, GO:0060021=ISS, GO:0060996=ISS, GO:0060997=ISS, GO:0051965=ISS, GO:0022407=IDA, GO:0048013=IDA, GO:0021952=IEA, GO:0001525=ISS, GO:0005524=IEA, GO:0048546=ISS, GO:0043088=IDA, GO:0022038=ISS, GO:0016477=IDA, GO:0005887=IDA, GO:0008046=IEA, GO:0050770=ISS} angiogenesis, axon guidance, axonal fasciculation, cell migration, central nervous system projection neuron axonogenesis, corpus callosum development, dendritic spine development, dendritic spine morphogenesis, digestive tract morphogenesis, ephrin receptor signaling pathway, palate development, positive regulation of synapse assembly, protein autophosphorylation, regulation of Cdc42 GTPase activity, regulation of Rac GTPase activity, regulation of axonogenesis, regulation of cell-cell adhesion, retinal ganglion cell axon guidance, substrate adhesion-dependent cell spreading, thymus development, urogenital system development dendrite, integral to plasma membrane ATP binding, axon guidance receptor activity, ephrin receptor activity Human UniProtKB:P54754 EPHB4 UniProtKB UniProtKB {GO:0005515=PMID:16867992, GO:0003007=GO_REF:0000024, GO:0005003=GO_REF:0000002, GO:0046777=PMID:8188704, GO:0048013=PMID:12734395, GO:0009986=PMID:12493773, GO:0005887=GO_REF:0000002, GO:0002042=PMID:12734395, GO:0001525=GO_REF:0000024, GO:0007155=PMID:12734395, GO:0004714=PMID:8188704, GO:0005524=GO_REF:0000038} Q96L35 EPH receptor B4, isoform CRA_b protein 20130413 {GO:0005515=IPI, GO:0003007=ISS, GO:0005003=IEA, GO:0046777=IDA, GO:0048013=IDA, GO:0009986=IDA, GO:0005887=IEA, GO:0002042=IDA, GO:0001525=ISS, GO:0007155=IDA, GO:0004714=IDA, GO:0005524=IEA} angiogenesis, cell adhesion, cell migration involved in sprouting angiogenesis, ephrin receptor signaling pathway, heart morphogenesis, protein autophosphorylation cell surface, integral to plasma membrane ATP binding, ephrin receptor activity, protein binding, transmembrane receptor protein tyrosine kinase activity Human UniProtKB-KW:KW-0067 EPHB6 PINC UniProtKB {GO:0005003=GO_REF:0000002, GO:0004672=GO_REF:0000002, GO:0048013=GO_REF:0000002, GO:0005887=GO_REF:0000002, GO:0004872=PMID:9207182, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000038, GO:0005524=GO_REF:0000037, GO:0035898=GO_REF:0000019, GO:0055074=GO_REF:0000019} O15197 Ephrin type-B receptor 6 protein 20030904 {GO:0005003=IEA, GO:0004672=IEA, GO:0048013=IEA, GO:0005887=IEA, GO:0004872=TAS, GO:0005576=IEA, GO:0016021=IEA, GO:0005524=IEA, GO:0035898=IEA, GO:0055074=IEA} calcium ion homeostasis, ephrin receptor signaling pathway, parathyroid hormone secretion extracellular region, integral to membrane, integral to plasma membrane ATP binding, ephrin receptor activity, protein kinase activity, receptor activity Human EPHX1 PINC UniProtKB {GO:0014070=GO_REF:0000019, GO:0033961=GO_REF:0000003, GO:0019439=GO_REF:0000037, GO:0006725=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0009636=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0004301=PMID:7516776} P07099 Epoxide hydrolase 1 protein 20030904 {GO:0014070=IEA, GO:0033961=IEA, GO:0019439=IEA, GO:0006725=IEA, GO:0005789=IEA, GO:0009636=IEA, GO:0016021=IEA, GO:0004301=TAS} aromatic compound catabolic process, cellular aromatic compound metabolic process, response to organic cyclic compound, response to toxic substance endoplasmic reticulum membrane, integral to membrane cis-stilbene-oxide hydrolase activity, epoxide hydrolase activity Human EPHX2 HPA UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0090181=PMID:18974052, GO:0006805=PMID:10862610, GO:0017144=PMID:10862610, GO:0003869=PMID:12574508, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0042803=PMID:18513744, GO:0005829=Reactome:REACT_150274, GO:0016791=PMID:15196990, GO:0042577=PMID:12574510, GO:0005737=GO_REF:0000052, GO:0006954=PMID:10862610, GO:0045909=PMID:10862610, GO:0033885=GO_REF:0000003, GO:0005777=PMID:18513744, GO:0042632=PMID:18974052, GO:0000287=PMID:12574510, GO:0005794=GO_REF:0000052, GO:0019373=Reactome:REACT_150417, GO:0072593=PMID:10862610, GO:0005730=GO_REF:0000052, GO:0006874=PMID:10862610, GO:0005102=PMID:20178365, GO:0009636=PMID:10862610, GO:0010628=GO_REF:0000019, GO:0016787=GO_REF:0000002, GO:0046839=PMID:12574510, GO:0016311=PMID:12574508, GO:0046272=PMID:8342951, GO:0008217=PMID:10862610, GO:0005925=GO_REF:0000052, GO:0004301=Reactome:REACT_150274} P34913 Bifunctional epoxide hydrolase 2 protein 20101115 {GO:0019369=TAS, GO:0090181=IMP, GO:0006805=NAS, GO:0017144=NAS, GO:0003869=IDA, GO:0044281=TAS, GO:0003824=IEA, GO:0042803=IDA, GO:0005829=TAS, GO:0016791=IDA, GO:0042577=IDA, GO:0005737=IDA, GO:0006954=NAS, GO:0045909=NAS, GO:0033885=IEA, GO:0005777=IDA, GO:0042632=IDA, GO:0000287=IDA, GO:0005794=IDA, GO:0019373=TAS, GO:0072593=NAS, GO:0005730=IDA, GO:0006874=NAS, GO:0005102=IPI, GO:0009636=NAS, GO:0010628=IEA, GO:0016787=IEA, GO:0046839=IDA, GO:0016311=IDA, GO:0046272=IDA, GO:0008217=NAS, GO:0005925=IDA, GO:0004301=TAS} arachidonic acid metabolic process, cellular calcium ion homeostasis, cholesterol homeostasis, dephosphorylation, drug metabolic process, epoxygenase P450 pathway, inflammatory response, phospholipid dephosphorylation, positive regulation of gene expression, positive regulation of vasodilation, reactive oxygen species metabolic process, regulation of blood pressure, regulation of cholesterol metabolic process, response to toxic substance, small molecule metabolic process, stilbene catabolic process, xenobiotic metabolic process Golgi apparatus, cytoplasm, cytosol, focal adhesion, nucleolus, peroxisome 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity, 4-nitrophenylphosphatase activity, catalytic activity, epoxide hydrolase activity, hydrolase activity, lipid phosphatase activity, magnesium ion binding, phosphatase activity, protein homodimerization activity, receptor binding Human EPM2A GOC UniProtKB {GO:0005515=PMID:15930137, GO:0005886=GO_REF:0000039, GO:0005783=GO_REF:0000039, GO:0005977=PMID:9931343, GO:0005634=GO_REF:0000039, GO:0035335=PMID:9931343, GO:0007399=GO_REF:0000019, GO:0005829=PMID:12915448, GO:0005737=PMID:17908927, GO:0006470=PMID:11001928, GO:0030246=GO_REF:0000002, GO:0007610=GO_REF:0000019, GO:0004722=PMID:11001928, GO:0008138=GO_REF:0000002, GO:2001070=GO_REF:0000002, GO:0005844=PMID:11001928, GO:0004725=PMID:11001928} O95278 Laforin protein 20130413 {GO:0005515=IPI, GO:0005886=IEA, GO:0005783=IEA, GO:0005977=NAS, GO:0005634=IEA, GO:0035335=NAS, GO:0007399=IEA, GO:0005829=IDA, GO:0005737=IDA, GO:0006470=IDA, GO:0030246=IEA, GO:0007610=IEA, GO:0004722=TAS, GO:0008138=IEA, GO:2001070=IEA, GO:0005844=IDA, GO:0004725=IDA} behavior, glycogen metabolic process, nervous system development, peptidyl-tyrosine dephosphorylation, protein dephosphorylation cytoplasm, cytosol, endoplasmic reticulum, nucleus, plasma membrane, polysome carbohydrate binding, protein binding, protein serine/threonine phosphatase activity, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity, starch binding Human EPM2AIP1 UniProtKB UniProtKB {GO:0005783=GO_REF:0000039} Q7L775 EPM2A-interacting protein 1 protein 20130413 {GO:0005783=IEA} endoplasmic reticulum Human UniProtKB-SubCell:SL-0095 EPN1 Reactome UniProtKB {GO:0007565=GO_REF:0000019, GO:0005886=Reactome:REACT_12527, GO:0042059=Reactome:REACT_12484, GO:0005634=GO_REF:0000039, GO:0001701=GO_REF:0000019, GO:0006897=GO_REF:0000019, GO:0008289=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0005905=GO_REF:0000039, GO:0007219=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0048568=GO_REF:0000019, GO:0008134=GO_REF:0000019} Q9Y6I3 Epsin-1 protein 20130213 {GO:0007565=IEA, GO:0005886=TAS, GO:0042059=TAS, GO:0005634=IEA, GO:0001701=IEA, GO:0006897=IEA, GO:0008289=IEA, GO:0005737=IEA, GO:0005905=IEA, GO:0007219=IEA, GO:0007173=TAS, GO:0048568=IEA, GO:0008134=IEA} Notch signaling pathway, embryonic organ development, endocytosis, epidermal growth factor receptor signaling pathway, female pregnancy, in utero embryonic development, negative regulation of epidermal growth factor receptor signaling pathway coated pit, cytoplasm, nucleus, plasma membrane lipid binding, transcription factor binding Human EPN2 ENSEMBL UniProtKB {GO:0007219=GO_REF:0000019, GO:0048568=GO_REF:0000019, GO:0030128=GO_REF:0000002, GO:0001701=GO_REF:0000019, GO:0008289=GO_REF:0000037, GO:0006897=GO_REF:0000037} O95208 Epsin-2 protein 20130413 {GO:0007219=IEA, GO:0048568=IEA, GO:0030128=IEA, GO:0001701=IEA, GO:0008289=IEA, GO:0006897=IEA} Notch signaling pathway, embryonic organ development, endocytosis, in utero embryonic development clathrin coat of endocytic vesicle lipid binding Human Ensembl:ENSMUSP00000136950 EPN3 UniProtKB UniProtKB {GO:0048471=GO_REF:0000039, GO:0030136=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0008289=GO_REF:0000037} Q9H201 Epsin-3 protein 20130413 {GO:0048471=IEA, GO:0030136=IEA, GO:0005634=IEA, GO:0008289=IEA} clathrin-coated vesicle, nucleus, perinuclear region of cytoplasm lipid binding Human UniProtKB-SubCell:SL-0198 EPO BHF-UCL UniProtKB {GO:0005515=PMID:9774108, GO:0042541=GO_REF:0000019, GO:0008284=PMID:9722506, GO:0043627=GO_REF:0000019, GO:0043499=PMID:14569084, GO:0009651=GO_REF:0000019, GO:0033189=GO_REF:0000019, GO:0008015=PMID:3838366, GO:0042523=PMID:9722506, GO:0061418=Reactome:REACT_120815, GO:0046579=PMID:9722506, GO:0005615=PMID:14569084, GO:0048678=GO_REF:0000019, GO:0032413=PMID:14569084, GO:0043249=GO_REF:0000037, GO:0018105=GO_REF:0000019, GO:0010766=PMID:14569084, GO:0051602=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0033033=GO_REF:0000019, GO:0005128=GO_REF:0000002, GO:0070555=GO_REF:0000019, GO:0071474=PMID:14569084, GO:0043066=PMID:14569084, GO:0007566=GO_REF:0000019, GO:0045740=PMID:9722506, GO:0007568=GO_REF:0000019, GO:0071456=Reactome:REACT_121311, GO:0006915=GO_REF:0000019, GO:0005576=Reactome:REACT_121407, GO:0033554=Reactome:REACT_120956, GO:0030295=GO_REF:0000019, GO:0033574=GO_REF:0000019, GO:0007165=PMID:3838366, GO:0005179=GO_REF:0000037, GO:0045666=GO_REF:0000019, GO:0055093=GO_REF:0000019, GO:0045893=PMID:9722506} P01588 Erythropoietin protein 20080530 {GO:0005515=IPI, GO:0042541=IEA, GO:0008284=IDA, GO:0043627=IEA, GO:0043499=IDA, GO:0009651=IEA, GO:0033189=IEA, GO:0008015=NAS, GO:0042523=IDA, GO:0061418=TAS, GO:0046579=IDA, GO:0005615=IDA, GO:0048678=IEA, GO:0032413=IDA, GO:0043249=IEA, GO:0018105=IEA, GO:0010766=IDA, GO:0051602=IEA, GO:0032496=IEA, GO:0033033=IEA, GO:0005128=IEA, GO:0070555=IEA, GO:0071474=IDA, GO:0043066=IDA, GO:0007566=IEA, GO:0045740=IDA, GO:0007568=IEA, GO:0071456=TAS, GO:0006915=IEA, GO:0005576=TAS, GO:0033554=TAS, GO:0030295=IEA, GO:0033574=IEA, GO:0007165=NAS, GO:0005179=IEA, GO:0045666=IEA, GO:0055093=IEA, GO:0045893=IDA} aging, apoptotic process, blood circulation, cellular hyperosmotic response, cellular response to hypoxia, cellular response to stress, embryo implantation, erythrocyte maturation, hemoglobin biosynthetic process, negative regulation of apoptotic process, negative regulation of ion transmembrane transporter activity, negative regulation of myeloid cell apoptotic process, negative regulation of sodium ion transport, peptidyl-serine phosphorylation, positive regulation of DNA replication, positive regulation of Ras protein signal transduction, positive regulation of cell proliferation, positive regulation of neuron differentiation, positive regulation of transcription, DNA-dependent, positive regulation of tyrosine phosphorylation of Stat5 protein, regulation of transcription from RNA polymerase II promoter in response to hypoxia, response to axon injury, response to electrical stimulus, response to estrogen stimulus, response to hyperoxia, response to interleukin-1, response to lipopolysaccharide, response to salt stress, response to testosterone stimulus, response to vitamin A, signal transduction extracellular region, extracellular space erythropoietin receptor binding, eukaryotic cell surface binding, hormone activity, protein binding, protein kinase activator activity Human EPOR GOC UniProtKB {GO:0005515=PMID:15644415, GO:0038162=PMID:8506290, GO:0005576=GO_REF:0000039, GO:0009790=GO_REF:0000019, GO:0042802=PMID:21058338, GO:0007507=GO_REF:0000019, GO:0046697=GO_REF:0000019, GO:0007165=PMID:1668606, GO:0007420=GO_REF:0000019, GO:0005887=PMID:1848667, GO:0016021=GO_REF:0000002, GO:0004888=GO_REF:0000002, GO:0004900=PMID:2163696} P19235 Erythropoietin receptor protein 20130413 {GO:0005515=IPI, GO:0038162=TAS, GO:0005576=IEA, GO:0009790=IEA, GO:0042802=IPI, GO:0007507=IEA, GO:0046697=IEA, GO:0007165=NAS, GO:0007420=IEA, GO:0005887=TAS, GO:0016021=IEA, GO:0004888=IEA, GO:0004900=IDA} brain development, decidualization, embryo development, erythropoietin-mediated signaling pathway, heart development, signal transduction extracellular region, integral to membrane, integral to plasma membrane erythropoietin receptor activity, identical protein binding, protein binding, transmembrane signaling receptor activity Human EPPK1 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000037, GO:0005198=GO_REF:0000029, GO:0005856=GO_REF:0000029} P58107 Epiplakin protein 20021104 {GO:0008150=ND, GO:0005737=IEA, GO:0005198=NAS, GO:0005856=NAS} biological_process cytoplasm, cytoskeleton structural molecule activity Human EPRS IntAct UniProtKB {GO:0005515=PMID:9556618, GO:0017148=PMID:23071094, GO:0010467=Reactome:REACT_71, GO:0035613=PMID:15479637, GO:0004818=Reactome:REACT_15345, GO:0004827=Reactome:REACT_15436, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_15516, GO:0006418=Reactome:REACT_15482, GO:0005737=PMID:8188258, GO:0006424=GO_REF:0000002, GO:0006433=GO_REF:0000002, GO:0006461=PMID:8188258, GO:0071346=PMID:15479637, GO:0030529=PMID:15479637} P07814 Bifunctional glutamate/proline--tRNA ligase protein 20130415 {GO:0005515=IPI, GO:0017148=IDA, GO:0010467=TAS, GO:0035613=IDA, GO:0004818=TAS, GO:0004827=TAS, GO:0005524=IEA, GO:0005829=TAS, GO:0006418=TAS, GO:0005737=TAS, GO:0006424=IEA, GO:0006433=IEA, GO:0006461=TAS, GO:0071346=IDA, GO:0030529=IDA} cellular response to interferon-gamma, gene expression, glutamyl-tRNA aminoacylation, negative regulation of translation, prolyl-tRNA aminoacylation, protein complex assembly, tRNA aminoacylation for protein translation cytoplasm, cytosol, ribonucleoprotein complex ATP binding, RNA stem-loop binding, glutamate-tRNA ligase activity, proline-tRNA ligase activity, protein binding Human UniProtKB:P41252 EPS15 HPA UniProtKB {GO:0005515=PMID:21762413, GO:0017124=GO_REF:0000037, GO:0060170=GO_REF:0000019, GO:0005886=PMID:15465819, GO:0008283=PMID:8183552, GO:0030122=GO_REF:0000019, GO:0032456=PMID:12807910, GO:0005509=GO_REF:0000002, GO:0042059=Reactome:REACT_12484, GO:0015031=GO_REF:0000037, GO:0005829=Reactome:REACT_12527, GO:0043231=GO_REF:0000052, GO:0006897=GO_REF:0000037, GO:0016050=PMID:9762922, GO:0005737=GO_REF:0000052, GO:0005905=PMID:9762922, GO:0007173=Reactome:REACT_9417, GO:0031901=GO_REF:0000039, GO:0048268=PMID:12807910} P42566 Epidermal growth factor receptor substrate 15 protein 20081203 {GO:0005515=IPI, GO:0017124=IEA, GO:0060170=IEA, GO:0005886=IDA, GO:0008283=TAS, GO:0030122=IEA, GO:0032456=IC, GO:0005509=IEA, GO:0042059=TAS, GO:0015031=IEA, GO:0005829=TAS, GO:0043231=IDA, GO:0006897=IEA, GO:0016050=TAS, GO:0005737=IDA, GO:0005905=TAS, GO:0007173=TAS, GO:0031901=IEA, GO:0048268=IDA} cell proliferation, clathrin coat assembly, endocytic recycling, endocytosis, epidermal growth factor receptor signaling pathway, negative regulation of epidermal growth factor receptor signaling pathway, protein transport, vesicle organization AP-2 adaptor complex, cilium membrane, coated pit, cytoplasm, cytosol, early endosome membrane, intracellular membrane-bounded organelle, plasma membrane SH3 domain binding, calcium ion binding, protein binding Human EPS15L1 Reactome UniProtKB {GO:0005905=GO_REF:0000039, GO:0007173=Reactome:REACT_9417, GO:0005886=Reactome:REACT_12527, GO:0005509=GO_REF:0000002, GO:0042059=Reactome:REACT_12484, GO:0005634=GO_REF:0000039, GO:0006897=GO_REF:0000037} Q9UBC2 Epidermal growth factor receptor substrate 15-like 1 protein 20130213 {GO:0005905=IEA, GO:0007173=TAS, GO:0005886=TAS, GO:0005509=IEA, GO:0042059=TAS, GO:0005634=IEA, GO:0006897=IEA} endocytosis, epidermal growth factor receptor signaling pathway, negative regulation of epidermal growth factor receptor signaling pathway coated pit, nucleus, plasma membrane calcium ion binding Human EPS8 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0008344=GO_REF:0000019, GO:0008283=PMID:8084614, GO:0008360=GO_REF:0000024, GO:0017146=GO_REF:0000019, GO:0035415=GO_REF:0000024, GO:0030426=GO_REF:0000039, GO:0070358=GO_REF:0000024, GO:0051016=GO_REF:0000024, GO:0030832=GO_REF:0000024, GO:0007173=PMID:8084614, GO:0016301=GO_REF:0000038, GO:0051764=GO_REF:0000024, GO:0051017=GO_REF:0000024, GO:0005938=GO_REF:0000024, GO:0010458=GO_REF:0000024, GO:0031532=GO_REF:0000019, GO:0014069=GO_REF:0000019, GO:0032420=GO_REF:0000024, GO:0003779=GO_REF:0000024, GO:0032587=GO_REF:0000024, GO:0007165=PMID:8084614, GO:0048365=GO_REF:0000024, GO:0036336=GO_REF:0000024, GO:0016601=GO_REF:0000024, GO:0048149=GO_REF:0000019, GO:0005070=PMID:8084614} Q12929 Epidermal growth factor receptor kinase substrate 8 protein 20130415 {GO:0005515=IPI, GO:0008344=IEA, GO:0008283=TAS, GO:0008360=ISS, GO:0017146=IEA, GO:0035415=ISS, GO:0030426=IEA, GO:0070358=ISS, GO:0051016=ISS, GO:0030832=ISS, GO:0007173=TAS, GO:0016301=IEA, GO:0051764=ISS, GO:0051017=ISS, GO:0005938=ISS, GO:0010458=ISS, GO:0031532=IEA, GO:0014069=IEA, GO:0032420=ISS, GO:0003779=ISS, GO:0032587=ISS, GO:0007165=TAS, GO:0048365=ISS, GO:0036336=ISS, GO:0016601=ISS, GO:0048149=IEA, GO:0005070=TAS} Rac protein signal transduction, actin crosslink formation, actin cytoskeleton reorganization, actin filament bundle assembly, actin polymerization-dependent cell motility, adult locomotory behavior, barbed-end actin filament capping, behavioral response to ethanol, cell proliferation, dendritic cell migration, epidermal growth factor receptor signaling pathway, exit from mitosis, regulation of actin filament length, regulation of cell shape, regulation of mitotic prometaphase, signal transduction N-methyl-D-aspartate selective glutamate receptor complex, cell cortex, growth cone, postsynaptic density, ruffle membrane, stereocilium Rac GTPase binding, SH3/SH2 adaptor activity, actin binding, kinase activity, protein binding Human UniProtKB:P49419 EPS8L1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000039, GO:0016301=GO_REF:0000038, GO:0005575=GO_REF:0000015} Q8TE68 Epidermal growth factor receptor kinase substrate 8-like protein 1 protein 20061106 {GO:0003674=ND, GO:0008150=ND, GO:0005737=IEA, GO:0016301=IEA, GO:0005575=ND} biological_process cellular_component, cytoplasm kinase activity, molecular_function Human EPS8L2 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052} Q9H6S3 Epidermal growth factor receptor kinase substrate 8-like protein 2 protein 20111111 {GO:0005737=IDA, GO:0005886=IDA} cytoplasm, plasma membrane Human EPS8L3 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q8TE67 Epidermal growth factor receptor kinase substrate 8-like protein 3 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 EPSTI1 null null {} null null null null {} null null null EPT1 Reactome UniProtKB {GO:0006646=Reactome:REACT_120919, GO:0016780=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0004307=GO_REF:0000003, GO:0005789=Reactome:REACT_121214, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0008654=GO_REF:0000002, GO:0006644=Reactome:REACT_120870, GO:0046872=GO_REF:0000037, GO:0046474=Reactome:REACT_121401} Q9C0D9 Ethanolaminephosphotransferase 1 protein 20110819 {GO:0006646=TAS, GO:0016780=IEA, GO:0016020=IEA, GO:0004307=IEA, GO:0005789=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0008654=IEA, GO:0006644=TAS, GO:0046872=IEA, GO:0046474=TAS} glycerophospholipid biosynthetic process, phosphatidylethanolamine biosynthetic process, phospholipid biosynthetic process, phospholipid metabolic process, small molecule metabolic process endoplasmic reticulum membrane, integral to membrane, membrane ethanolaminephosphotransferase activity, metal ion binding, phosphotransferase activity, for other substituted phosphate groups Human EPX ENSEMBL UniProtKB {GO:0032753=GO_REF:0000019, GO:0004601=GO_REF:0000003, GO:0032693=GO_REF:0000019, GO:0032714=GO_REF:0000019, GO:0002215=GO_REF:0000019, GO:0042744=GO_REF:0000037, GO:0072677=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0020037=GO_REF:0000002} P11678 Eosinophil peroxidase protein 20130413 {GO:0032753=IEA, GO:0004601=IEA, GO:0032693=IEA, GO:0032714=IEA, GO:0002215=IEA, GO:0042744=IEA, GO:0072677=IEA, GO:0046872=IEA, GO:0020037=IEA} defense response to nematode, eosinophil migration, hydrogen peroxide catabolic process, negative regulation of interleukin-10 production, negative regulation of interleukin-5 production, positive regulation of interleukin-4 production heme binding, metal ion binding, peroxidase activity Human Ensembl:ENSMUSP00000050497 ERAL1 UniProtKB UniProtKB {GO:0005759=PMID:20604745, GO:0003723=GO_REF:0000029, GO:0005743=GO_REF:0000039, GO:0019843=PMID:20604745, GO:0043024=PMID:20604745, GO:0005525=GO_REF:0000029, GO:0000028=PMID:20604745} O75616 GTPase Era, mitochondrial protein 20101217 {GO:0005759=IDA, GO:0003723=NAS, GO:0005743=IEA, GO:0019843=IDA, GO:0043024=IDA, GO:0005525=NAS, GO:0000028=IMP} ribosomal small subunit assembly mitochondrial inner membrane, mitochondrial matrix GTP binding, RNA binding, rRNA binding, ribosomal small subunit binding Human ERAP1 BHF-UCL UniProtKB {GO:0005515=PMID:18445477, GO:0005138=PMID:12748171, GO:0002474=Reactome:REACT_75820, GO:0005783=PMID:12748171, GO:0005576=PMID:11056387, GO:0001525=PMID:15691326, GO:0005151=PMID:15691326, GO:0045766=GO_REF:0000019, GO:0005829=PMID:10220586, GO:0009617=PMID:16034137, GO:0005737=GO_REF:0000019, GO:0019885=PMID:15691326, GO:0004177=PMID:12748171, GO:0045088=PMID:12748171, GO:0006508=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0008217=PMID:15691326, GO:0008235=PMID:10220586, GO:0005788=Reactome:REACT_75798, GO:0045444=PMID:11056387, GO:0008270=PMID:10220586, GO:0016021=PMID:12748171, GO:0006509=PMID:12748171, GO:0008237=GO_REF:0000002} Q9NZ08 Endoplasmic reticulum aminopeptidase 1 protein 20081121 {GO:0005515=IPI, GO:0005138=IPI, GO:0002474=TAS, GO:0005783=NAS, GO:0005576=IDA, GO:0001525=TAS, GO:0005151=TAS, GO:0045766=IEA, GO:0005829=NAS, GO:0009617=IEP, GO:0005737=IEA, GO:0019885=TAS, GO:0004177=IDA, GO:0045088=NAS, GO:0006508=IEA, GO:0005789=IEA, GO:0008217=TAS, GO:0008235=IDA, GO:0005788=TAS, GO:0045444=NAS, GO:0008270=NAS, GO:0016021=NAS, GO:0006509=IDA, GO:0008237=IEA} angiogenesis, antigen processing and presentation of endogenous peptide antigen via MHC class I, antigen processing and presentation of peptide antigen via MHC class I, fat cell differentiation, membrane protein ectodomain proteolysis, positive regulation of angiogenesis, proteolysis, regulation of blood pressure, regulation of innate immune response, response to bacterium cytoplasm, cytosol, endoplasmic reticulum, endoplasmic reticulum lumen, endoplasmic reticulum membrane, extracellular region, integral to membrane aminopeptidase activity, interleukin-1, Type II receptor binding, interleukin-6 receptor binding, metalloexopeptidase activity, metallopeptidase activity, protein binding, zinc ion binding Human ERAP2 Reactome UniProtKB {GO:0002474=Reactome:REACT_75820, GO:0004177=PMID:12799365, GO:0019885=PMID:15691326, GO:0008217=PMID:12799365, GO:0005789=GO_REF:0000039, GO:0006508=GO_REF:0000037, GO:0005788=Reactome:REACT_75798, GO:0008270=PMID:12799365, GO:0016021=GO_REF:0000037, GO:0008237=PMID:12799365} Q6P179 Endoplasmic reticulum aminopeptidase 2 protein 20101029 {GO:0002474=TAS, GO:0004177=IDA, GO:0019885=TAS, GO:0008217=TAS, GO:0005789=IEA, GO:0006508=IEA, GO:0005788=TAS, GO:0008270=TAS, GO:0016021=IEA, GO:0008237=IDA} antigen processing and presentation of endogenous peptide antigen via MHC class I, antigen processing and presentation of peptide antigen via MHC class I, proteolysis, regulation of blood pressure endoplasmic reticulum lumen, endoplasmic reticulum membrane, integral to membrane aminopeptidase activity, metallopeptidase activity, zinc ion binding Human ERAS UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q7Z444 GTPase ERas protein 20130413 {GO:0005886=IEA, GO:0007264=IEA, GO:0003924=IEA, GO:0005525=IEA} small GTPase mediated signal transduction plasma membrane GTP binding, GTPase activity Human UniProtKB-SubCell:SL-0039 ERBB2 GOC UniProtKB {GO:0033088=GO_REF:0000019, GO:0005515=PMID:22939624, GO:0030307=PMID:21555369, GO:0030879=PMID:15504738, GO:0042802=PMID:21480528, GO:0005006=PMID:15504738, GO:0007507=PMID:15504738, GO:0046777=PMID:7556068, GO:0007173=Reactome:REACT_9417, GO:0007411=Reactome:REACT_18266, GO:0046983=PMID:12000754, GO:0070372=PMID:16314522, GO:0043125=PMID:9590694, GO:0023014=PMID:10851066, GO:0050679=PMID:10572067, GO:0046982=PMID:7556068, GO:0019903=PMID:15899872, GO:0014065=PMID:7556068, GO:0045785=PMID:7556068, GO:0043235=PMID:7556068, GO:0008045=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0032321=GO_REF:0000024, GO:0045087=Reactome:REACT_6802, GO:0042060=PMID:12646923, GO:0007422=GO_REF:0000019, GO:0010008=PMID:16314522, GO:0004888=PMID:7514177, GO:0048471=GO_REF:0000039, GO:0005886=Reactome:REACT_147854, GO:0008283=PMID:10851066, GO:0005634=PMID:16314522, GO:0016323=PMID:12646923, GO:0005737=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0019838=PMID:7514177, GO:0007528=GO_REF:0000019, GO:0045943=PMID:21555369, GO:0043406=PMID:10572067, GO:0045945=PMID:19372587, GO:0001042=PMID:21555369, GO:0048011=Reactome:REACT_11061, GO:0048015=Reactome:REACT_12464, GO:0042552=GO_REF:0000019, GO:0045765=PMID:15609325, GO:0032886=PMID:20937854, GO:0045727=PMID:21555369, GO:0008022=PMID:15520177, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0007399=PMID:15504738, GO:0007165=PMID:10572067, GO:0016020=GO_REF:0000002, GO:0001934=GO_REF:0000024, GO:0006468=PMID:10851066, GO:0016021=PMID:15609325, GO:0004713=PMID:7556068, GO:0004714=PMID:7514177, GO:0007169=PMID:7556068, GO:0004716=GO_REF:0000002, GO:0007166=PMID:9685399, GO:0007167=PMID:9590694} P04626 Receptor tyrosine-protein kinase erbB-2 protein 20130413 {GO:0033088=IEA, GO:0005515=IPI, GO:0030307=IMP, GO:0030879=TAS, GO:0042802=IPI, GO:0005006=NAS, GO:0007507=TAS, GO:0046777=IDA, GO:0007173=TAS, GO:0007411=TAS, GO:0046983=NAS, GO:0070372=IMP, GO:0043125=TAS, GO:0023014=TAS, GO:0050679=IDA, GO:0046982=IPI, GO:0019903=IPI, GO:0014065=IDA, GO:0045785=IDA, GO:0043235=TAS, GO:0008045=IEA, GO:0008543=TAS, GO:0032321=ISS, GO:0045087=TAS, GO:0042060=IDA, GO:0007422=IEA, GO:0010008=IDA, GO:0004888=IDA, GO:0048471=IEA, GO:0005886=TAS, GO:0008283=TAS, GO:0005634=IDA, GO:0016323=IDA, GO:0005737=IEA, GO:0016324=IEA, GO:0019838=IDA, GO:0007528=IEA, GO:0045943=IMP, GO:0043406=IDA, GO:0045945=IDA, GO:0001042=IDA, GO:0048011=TAS, GO:0048015=TAS, GO:0042552=IEA, GO:0045765=NAS, GO:0032886=IDA, GO:0045727=IMP, GO:0008022=IPI, GO:0005524=IEA, GO:0006351=IEA, GO:0007399=TAS, GO:0007165=IDA, GO:0016020=IEA, GO:0001934=ISS, GO:0006468=TAS, GO:0016021=NAS, GO:0004713=IDA, GO:0004714=IDA, GO:0007169=TAS, GO:0004716=IEA, GO:0007166=IDA, GO:0007167=TAS} axon guidance, cell proliferation, cell surface receptor signaling pathway, enzyme linked receptor protein signaling pathway, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, heart development, innate immune response, mammary gland development, motor neuron axon guidance, myelination, negative regulation of immature T cell proliferation in thymus, nervous system development, neuromuscular junction development, neurotrophin TRK receptor signaling pathway, peripheral nervous system development, phosphatidylinositol 3-kinase cascade, phosphatidylinositol-mediated signaling, positive regulation of MAP kinase activity, positive regulation of Rho GTPase activity, positive regulation of cell adhesion, positive regulation of cell growth, positive regulation of epithelial cell proliferation, positive regulation of protein phosphorylation, positive regulation of transcription from RNA polymerase I promoter, positive regulation of transcription from RNA polymerase III promoter, positive regulation of translation, protein autophosphorylation, protein phosphorylation, regulation of ERK1 and ERK2 cascade, regulation of angiogenesis, regulation of microtubule-based process, signal transduction, signal transduction by phosphorylation, transcription, DNA-dependent, transmembrane receptor protein tyrosine kinase signaling pathway, wound healing apical plasma membrane, basolateral plasma membrane, cytoplasm, endosome membrane, integral to membrane, membrane, nucleus, perinuclear region of cytoplasm, plasma membrane, receptor complex ATP binding, ErbB-3 class receptor binding, RNA polymerase I core binding, epidermal growth factor-activated receptor activity, growth factor binding, identical protein binding, protein C-terminus binding, protein binding, protein dimerization activity, protein heterodimerization activity, protein phosphatase binding, protein tyrosine kinase activity, receptor signaling protein tyrosine kinase activity, transmembrane receptor protein tyrosine kinase activity, transmembrane signaling receptor activity Human ERBB2IP HPA UniProtKB {GO:0005515=PMID:16714539, GO:0030056=PMID:11375975, GO:0031965=GO_REF:0000039, GO:0005886=GO_REF:0000052, GO:0045104=PMID:11375975, GO:0005634=PMID:11375975, GO:0006605=GO_REF:0000019, GO:0045175=PMID:11375975, GO:0005604=PMID:10878805, GO:0045197=PMID:11375975, GO:0007165=PMID:10878805, GO:0005176=PMID:11375975, GO:0005737=PMID:11375975, GO:0007049=PMID:11375975, GO:0009925=PMID:11375975, GO:0005178=PMID:11375975, GO:0007173=PMID:11375975, GO:0007229=PMID:11375975, GO:0005200=PMID:11375975, GO:0016049=PMID:11375975, GO:0007155=PMID:11375975} Q96RT1 Protein LAP2 protein 20120912 {GO:0005515=IPI, GO:0030056=IDA, GO:0031965=IEA, GO:0005886=IDA, GO:0045104=NAS, GO:0005634=IDA, GO:0006605=IEA, GO:0045175=NAS, GO:0005604=TAS, GO:0045197=NAS, GO:0007165=TAS, GO:0005176=TAS, GO:0005737=IDA, GO:0007049=NAS, GO:0009925=NAS, GO:0005178=IPI, GO:0007173=TAS, GO:0007229=NAS, GO:0005200=NAS, GO:0016049=NAS, GO:0007155=NAS} basal protein localization, cell adhesion, cell cycle, cell growth, epidermal growth factor receptor signaling pathway, establishment or maintenance of epithelial cell apical/basal polarity, integrin-mediated signaling pathway, intermediate filament cytoskeleton organization, protein targeting, signal transduction basal plasma membrane, basement membrane, cytoplasm, hemidesmosome, nuclear membrane, nucleus, plasma membrane ErbB-2 class receptor binding, integrin binding, protein binding, structural constituent of cytoskeleton Human ERBB3 GOC UniProtKB {GO:0005515=PMID:22439932, GO:0005886=PMID:17701904, GO:0061098=PMID:7556068, GO:0051048=PMID:10559227, GO:0051402=PMID:17701904, GO:0005615=PMID:11389077, GO:0042803=PMID:11389077, GO:0007507=GO_REF:0000024, GO:0016323=PMID:12646923, GO:0014037=GO_REF:0000024, GO:0043524=GO_REF:0000024, GO:0016324=GO_REF:0000019, GO:0030296=PMID:7556068, GO:0007173=Reactome:REACT_9417, GO:0019838=PMID:7514177, GO:0042127=PMID:11389077, GO:0009968=PMID:11389077, GO:0048011=Reactome:REACT_11061, GO:0046982=PMID:7556068, GO:0003197=GO_REF:0000019, GO:0021545=GO_REF:0000024, GO:0048015=Reactome:REACT_12464, GO:0014068=PMID:17701904, GO:0016328=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0014065=PMID:7556068, GO:0043235=PMID:7514177, GO:0007165=PMID:10572067, GO:0007162=PMID:7556068, GO:0004672=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0005887=PMID:2687875, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0042060=PMID:12646923, GO:0007422=GO_REF:0000024, GO:0004713=PMID:7556068, GO:0004714=GO_REF:0000002, GO:0007169=PMID:7514177, GO:0004888=PMID:7514177} P21860 Receptor tyrosine-protein kinase erbB-3 protein 20130413 {GO:0005515=IPI, GO:0005886=TAS, GO:0061098=IDA, GO:0051048=IDA, GO:0051402=IMP, GO:0005615=IDA, GO:0042803=NAS, GO:0007507=ISS, GO:0016323=IDA, GO:0014037=ISS, GO:0043524=ISS, GO:0016324=IEA, GO:0030296=IDA, GO:0007173=TAS, GO:0019838=ISS, GO:0042127=IDA, GO:0009968=IDA, GO:0048011=TAS, GO:0046982=IPI, GO:0003197=IEA, GO:0021545=ISS, GO:0048015=TAS, GO:0014068=TAS, GO:0016328=IEA, GO:0005524=IEA, GO:0014065=IDA, GO:0043235=ISS, GO:0007165=IDA, GO:0007162=IDA, GO:0004672=IEA, GO:0016020=IEA, GO:0005887=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0042060=NAS, GO:0007422=ISS, GO:0004713=IDA, GO:0004714=IEA, GO:0007169=ISS, GO:0004888=ISS} Schwann cell differentiation, cranial nerve development, endocardial cushion development, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, heart development, innate immune response, negative regulation of cell adhesion, negative regulation of neuron apoptotic process, negative regulation of secretion, negative regulation of signal transduction, neuron apoptotic process, neurotrophin TRK receptor signaling pathway, peripheral nervous system development, phosphatidylinositol 3-kinase cascade, phosphatidylinositol-mediated signaling, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of protein tyrosine kinase activity, regulation of cell proliferation, signal transduction, transmembrane receptor protein tyrosine kinase signaling pathway, wound healing apical plasma membrane, basolateral plasma membrane, extracellular space, integral to plasma membrane, lateral plasma membrane, membrane, plasma membrane, receptor complex ATP binding, growth factor binding, protein binding, protein heterodimerization activity, protein homodimerization activity, protein kinase activity, protein tyrosine kinase activator activity, protein tyrosine kinase activity, transmembrane receptor protein tyrosine kinase activity, transmembrane signaling receptor activity Human ERBB4 HPA UniProtKB {GO:0005515=PMID:22939624, GO:0060045=GO_REF:0000024, GO:0021551=GO_REF:0000024, GO:0005154=PMID:8617750, GO:0044212=PMID:15534001, GO:0001755=GO_REF:0000024, GO:0042803=PMID:18334220, GO:0009880=GO_REF:0000024, GO:0007507=GO_REF:0000024, GO:0060644=GO_REF:0000024, GO:0046777=PMID:18334220, GO:0007173=Reactome:REACT_9417, GO:0005759=Reactome:REACT_115552, GO:0070374=PMID:10348342, GO:0030334=GO_REF:0000024, GO:0018108=PMID:18334220, GO:0045165=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0021889=GO_REF:0000024, GO:0005654=Reactome:REACT_116083, GO:0045893=PMID:15534001, GO:0008284=PMID:9135143, GO:0008285=PMID:17120616, GO:0005886=Reactome:REACT_147854, GO:0008283=PMID:8383326, GO:0042523=PMID:16837552, GO:0005634=GO_REF:0000052, GO:0005829=Reactome:REACT_116068, GO:0005739=PMID:16778220, GO:0016323=PMID:12646923, GO:0005737=GO_REF:0000052, GO:0061026=GO_REF:0000024, GO:2000366=PMID:15534001, GO:0048011=Reactome:REACT_11061, GO:0048015=Reactome:REACT_12464, GO:0005730=GO_REF:0000052, GO:0006915=PMID:16778220, GO:0005576=Reactome:REACT_115992, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0007399=GO_REF:0000024, GO:0007165=PMID:10572067, GO:0016477=PMID:9135143, GO:0007595=PMID:15534001, GO:0016020=GO_REF:0000002, GO:0001934=PMID:15534001, GO:0004713=PMID:18334220, GO:0016021=GO_REF:0000037, GO:0004714=PMID:18334220, GO:0007169=PMID:10353604, GO:0004716=GO_REF:0000002, GO:0060749=GO_REF:0000024} Q15303 Receptor tyrosine-protein kinase erbB-4 protein 20090616 {GO:0005515=IPI, GO:0060045=ISS, GO:0021551=ISS, GO:0005154=IPI, GO:0044212=IMP, GO:0001755=ISS, GO:0042803=IPI, GO:0009880=ISS, GO:0007507=ISS, GO:0060644=ISS, GO:0046777=IDA, GO:0007173=TAS, GO:0005759=TAS, GO:0070374=IMP, GO:0030334=ISS, GO:0018108=IDA, GO:0045165=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:0021889=ISS, GO:0005654=TAS, GO:0045893=IMP, GO:0008284=IMP, GO:0008285=IMP, GO:0005886=TAS, GO:0008283=TAS, GO:0042523=IMP, GO:0005634=IDA, GO:0005829=TAS, GO:0005739=IDA, GO:0016323=IDA, GO:0005737=IDA, GO:0061026=ISS, GO:2000366=IMP, GO:0048011=TAS, GO:0048015=TAS, GO:0005730=IDA, GO:0006915=IMP, GO:0005576=TAS, GO:0005524=IEA, GO:0006351=IEA, GO:0007399=ISS, GO:0007165=IDA, GO:0016477=IDA, GO:0007595=IMP, GO:0016020=IEA, GO:0001934=TAS, GO:0004713=IDA, GO:0016021=IEA, GO:0004714=IDA, GO:0007169=IDA, GO:0004716=IEA, GO:0060749=ISS} apoptotic process, cardiac muscle tissue regeneration, cell fate commitment, cell migration, cell proliferation, central nervous system morphogenesis, embryonic pattern specification, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, heart development, innate immune response, lactation, mammary gland alveolus development, mammary gland epithelial cell differentiation, negative regulation of cell proliferation, nervous system development, neural crest cell migration, neurotrophin TRK receptor signaling pathway, olfactory bulb interneuron differentiation, peptidyl-tyrosine phosphorylation, phosphatidylinositol-mediated signaling, positive regulation of ERK1 and ERK2 cascade, positive regulation of STAT protein import into nucleus, positive regulation of cardiac muscle cell proliferation, positive regulation of cell proliferation, positive regulation of protein phosphorylation, positive regulation of transcription, DNA-dependent, positive regulation of tyrosine phosphorylation of Stat5 protein, protein autophosphorylation, regulation of cell migration, signal transduction, transcription, DNA-dependent, transmembrane receptor protein tyrosine kinase signaling pathway basolateral plasma membrane, cytoplasm, cytosol, extracellular region, integral to membrane, membrane, mitochondrial matrix, mitochondrion, nucleolus, nucleoplasm, nucleus, plasma membrane ATP binding, epidermal growth factor receptor binding, protein binding, protein homodimerization activity, protein tyrosine kinase activity, receptor signaling protein tyrosine kinase activity, transcription regulatory region DNA binding, transmembrane receptor protein tyrosine kinase activity Human ERC1 UniProtKB UniProtKB {GO:0005515=PMID:12391317, GO:0017137=GO_REF:0000019, GO:0006355=PMID:15218148, GO:0007252=PMID:15218148, GO:0008385=PMID:15218148, GO:0007275=PMID:15218148, GO:0015031=GO_REF:0000037, GO:0043522=PMID:15218148, GO:0042734=PMID:12391317, GO:0005737=PMID:15218148, GO:0051092=PMID:15218148, GO:0000139=GO_REF:0000039, GO:0042147=GO_REF:0000019} Q8IUD2 ELKS/Rab6-interacting/CAST family member 1 protein 20051024 {GO:0005515=IPI, GO:0017137=IEA, GO:0006355=NAS, GO:0007252=IDA, GO:0008385=IDA, GO:0007275=NAS, GO:0015031=IEA, GO:0043522=NAS, GO:0042734=TAS, GO:0005737=TAS, GO:0051092=TAS, GO:0000139=IEA, GO:0042147=IEA} I-kappaB phosphorylation, multicellular organismal development, positive regulation of NF-kappaB transcription factor activity, protein transport, regulation of transcription, DNA-dependent, retrograde transport, endosome to Golgi Golgi membrane, IkappaB kinase complex, cytoplasm, presynaptic membrane Rab GTPase binding, leucine zipper domain binding, protein binding Human ERC2 IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0042734=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0005856=GO_REF:0000039, GO:0030426=GO_REF:0000024} O15083 ERC protein 2 protein 20130415 {GO:0005515=IPI, GO:0042734=ISS, GO:0005737=IEA, GO:0030054=IEA, GO:0005856=IEA, GO:0030426=ISS} cell junction, cytoplasm, cytoskeleton, growth cone, presynaptic membrane protein binding Human UniProtKB:P10242 ERCC1 HPA UniProtKB {GO:0005515=PMID:8197175, GO:0051276=GO_REF:0000019, GO:0009650=GO_REF:0000019, GO:0010165=GO_REF:0000019, GO:0048477=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0010259=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0007281=GO_REF:0000019, GO:0006302=GO_REF:0000019, GO:0000720=GO_REF:0000019, GO:0000109=PMID:3290851, GO:0005737=GO_REF:0000052, GO:0006295=PMID:7657672, GO:0003697=PMID:17720715, GO:0035264=GO_REF:0000019, GO:0006296=PMID:7657672, GO:0009744=GO_REF:0000019, GO:0048568=GO_REF:0000019, GO:0035166=GO_REF:0000019, GO:0006979=PMID:17614221, GO:0000784=PMID:14690602, GO:0043066=GO_REF:0000019, GO:0007584=GO_REF:0000019, GO:0045190=GO_REF:0000019, GO:0019904=PMID:17720715, GO:0005730=GO_REF:0000052, GO:0006310=PMID:11707424, GO:0008022=PMID:9722633, GO:0006312=PMID:8811092, GO:0003684=PMID:17720715, GO:0006949=GO_REF:0000019, GO:0006281=Reactome:REACT_216, GO:0004519=GO_REF:0000002, GO:0006283=Reactome:REACT_1628, GO:0043566=PMID:14734547, GO:0000014=PMID:7559382, GO:0005654=Reactome:REACT_2163, GO:0032205=PMID:17055345, GO:0001302=GO_REF:0000019, GO:0006289=Reactome:REACT_1826, GO:0000718=Reactome:REACT_311, GO:0008584=GO_REF:0000019} P07992 DNA excision repair protein ERCC-1 protein 20101115 {GO:0005515=IPI, GO:0051276=IEA, GO:0009650=IEA, GO:0010165=IEA, GO:0048477=IEA, GO:0008283=IEA, GO:0005634=IDA, GO:0010259=IEA, GO:0007283=IEA, GO:0007281=IEA, GO:0006302=IEA, GO:0000720=IEA, GO:0000109=IDA, GO:0005737=IDA, GO:0006295=IMP, GO:0003697=IDA, GO:0035264=IEA, GO:0006296=IMP, GO:0009744=IEA, GO:0048568=IEA, GO:0035166=IEA, GO:0006979=IMP, GO:0000784=IDA, GO:0043066=IEA, GO:0007584=IEA, GO:0045190=IEA, GO:0019904=IPI, GO:0005730=IDA, GO:0006310=IGI, GO:0008022=IPI, GO:0006312=IMP, GO:0003684=IDA, GO:0006949=IEA, GO:0006281=TAS, GO:0004519=IEA, GO:0006283=TAS, GO:0043566=IDA, GO:0000014=IDA, GO:0005654=TAS, GO:0032205=IMP, GO:0001302=IEA, GO:0006289=TAS, GO:0000718=TAS, GO:0008584=IEA} DNA recombination, DNA repair, UV protection, cell proliferation, chromosome organization, double-strand break repair, embryonic organ development, germ cell development, isotype switching, male gonad development, mitotic recombination, multicellular organism growth, multicellular organismal aging, negative regulation of apoptotic process, negative regulation of telomere maintenance, nucleotide-excision repair, nucleotide-excision repair, DNA damage removal, nucleotide-excision repair, DNA incision, 3'-to lesion, nucleotide-excision repair, DNA incision, 5'-to lesion, oogenesis, post-embryonic hemopoiesis, pyrimidine dimer repair by nucleotide-excision repair, replicative cell aging, response to X-ray, response to nutrient, response to oxidative stress, response to sucrose stimulus, spermatogenesis, syncytium formation, transcription-coupled nucleotide-excision repair cytoplasm, nuclear chromosome, telomeric region, nucleolus, nucleoplasm, nucleotide-excision repair complex, nucleus damaged DNA binding, endonuclease activity, protein C-terminus binding, protein binding, protein domain specific binding, single-stranded DNA binding, single-stranded DNA specific endodeoxyribonuclease activity, structure-specific DNA binding Human ERCC2 GOC UniProtKB {GO:0005515=PMID:11445587, GO:0010467=Reactome:REACT_71, GO:0006368=Reactome:REACT_2089, GO:0009650=PMID:2835663, GO:0006367=Reactome:REACT_1851, GO:0006366=Reactome:REACT_1366, GO:0000441=GO_REF:0000019, GO:0006363=Reactome:REACT_1074, GO:0006362=Reactome:REACT_2204, GO:0006361=Reactome:REACT_1974, GO:0006360=Reactome:REACT_1309, GO:0009791=GO_REF:0000019, GO:0030198=GO_REF:0000019, GO:0006979=PMID:17614221, GO:0008094=PMID:9852112, GO:0019907=PMID:8692842, GO:0007568=GO_REF:0000019, GO:0005819=PMID:20797633, GO:0006370=Reactome:REACT_1470, GO:0001701=GO_REF:0000019, GO:0006281=Reactome:REACT_216, GO:0006283=Reactome:REACT_1628, GO:0043388=GO_REF:0000019, GO:0043139=PMID:11445587, GO:0000075=PMID:17088560, GO:0005654=Reactome:REACT_2233, GO:0043588=GO_REF:0000019, GO:0006289=Reactome:REACT_1826, GO:0045893=PMID:8692842, GO:0022415=Reactome:REACT_6361, GO:0035315=PMID:11335038, GO:0021510=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:0005634=PMID:20797633, GO:0044281=Reactome:REACT_111217, GO:0030282=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005737=PMID:20797633, GO:0043249=GO_REF:0000019, GO:0004003=GO_REF:0000002, GO:0007059=PMID:20797633, GO:0035264=GO_REF:0000019, GO:0040016=GO_REF:0000019, GO:0045944=PMID:8692841, GO:0048820=GO_REF:0000019, GO:0016032=Reactome:REACT_6256, GO:0001666=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0051539=GO_REF:0000037, GO:0006915=GO_REF:0000019, GO:0006917=PMID:8675009, GO:0060218=GO_REF:0000019, GO:0008022=PMID:10801852, GO:0032289=GO_REF:0000019, GO:0008353=PMID:9852112, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0050434=Reactome:REACT_6162, GO:0047485=PMID:8652557, GO:0004672=PMID:9852112, GO:0019048=GO_REF:0000037, GO:0006468=PMID:9852112, GO:0000718=Reactome:REACT_311, GO:0005675=PMID:9852112, GO:0033683=PMID:8692841, GO:0071817=PMID:20797633} P18074 TFIIH basal transcription factor complex helicase XPD subunit protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0006368=TAS, GO:0009650=IGI, GO:0006367=TAS, GO:0006366=TAS, GO:0000441=IEA, GO:0006363=TAS, GO:0006362=TAS, GO:0006361=TAS, GO:0006360=TAS, GO:0009791=IEA, GO:0030198=IEA, GO:0006979=IMP, GO:0008094=IDA, GO:0019907=IDA, GO:0007568=IEA, GO:0005819=IDA, GO:0006370=TAS, GO:0001701=IEA, GO:0006281=TAS, GO:0006283=TAS, GO:0043388=IEA, GO:0043139=IDA, GO:0000075=IMP, GO:0005654=TAS, GO:0043588=IEA, GO:0006289=TAS, GO:0045893=IDA, GO:0022415=TAS, GO:0035315=IMP, GO:0021510=IEA, GO:0008283=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0030282=IEA, GO:0046872=IEA, GO:0005737=IDA, GO:0043249=IEA, GO:0004003=IEA, GO:0007059=IMP, GO:0035264=IEA, GO:0040016=IEA, GO:0045944=IDA, GO:0048820=IEA, GO:0016032=TAS, GO:0001666=IEA, GO:0043066=IEA, GO:0051539=IEA, GO:0006915=IEA, GO:0006917=IMP, GO:0060218=IEA, GO:0008022=IPI, GO:0032289=IEA, GO:0008353=IDA, GO:0003677=IEA, GO:0005524=IEA, GO:0050434=TAS, GO:0047485=IPI, GO:0004672=IDA, GO:0019048=IEA, GO:0006468=IDA, GO:0000718=TAS, GO:0005675=IDA, GO:0033683=IMP, GO:0071817=IDA} 7-methylguanosine mRNA capping, DNA repair, UV protection, aging, apoptotic process, bone mineralization, cell cycle checkpoint, cell proliferation, central nervous system myelin formation, chromosome segregation, embryonic cleavage, erythrocyte maturation, extracellular matrix organization, gene expression, hair cell differentiation, hair follicle maturation, hematopoietic stem cell differentiation, in utero embryonic development, induction of apoptosis, multicellular organism growth, negative regulation of apoptotic process, nucleotide-excision repair, nucleotide-excision repair, DNA damage removal, nucleotide-excision repair, DNA incision, positive regulation of DNA binding, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of viral transcription, post-embryonic development, protein phosphorylation, response to hypoxia, response to oxidative stress, skin development, small molecule metabolic process, spinal cord development, termination of RNA polymerase I transcription, transcription elongation from RNA polymerase I promoter, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase I promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase I promoter, transcription initiation from RNA polymerase II promoter, transcription-coupled nucleotide-excision repair, viral reproduction, viral reproductive process, virus-host interaction MMXD complex, SSL2-core TFIIH complex, cyclin-dependent protein kinase activating kinase holoenzyme complex, cytoplasm, holo TFIIH complex, nucleoplasm, nucleus, spindle 4 iron, 4 sulfur cluster binding, 5'-3' DNA helicase activity, ATP binding, ATP-dependent DNA helicase activity, DNA binding, DNA-dependent ATPase activity, RNA polymerase II carboxy-terminal domain kinase activity, metal ion binding, protein C-terminus binding, protein N-terminus binding, protein binding, protein kinase activity Human ERCC3 IntAct UniProtKB {GO:0005515=PMID:10734143, GO:0010467=Reactome:REACT_71, GO:0009650=GO_REF:0000019, GO:0006368=Reactome:REACT_2089, GO:0006367=Reactome:REACT_1851, GO:0006366=Reactome:REACT_1366, GO:0000441=GO_REF:0000019, GO:0006363=Reactome:REACT_1074, GO:0006362=Reactome:REACT_2204, GO:0006361=Reactome:REACT_1974, GO:0006360=Reactome:REACT_1309, GO:0009411=PMID:17509950, GO:0006979=PMID:17614221, GO:0008094=PMID:9852112, GO:0032564=GO_REF:0000019, GO:0006370=Reactome:REACT_1470, GO:0006281=Reactome:REACT_216, GO:0006283=Reactome:REACT_1628, GO:0000075=PMID:17088560, GO:0043138=PMID:17466626, GO:0005654=Reactome:REACT_2233, GO:0006289=Reactome:REACT_1826, GO:0008134=PMID:9173976, GO:0035315=PMID:11335038, GO:0022415=Reactome:REACT_6361, GO:0005634=PMID:8663148, GO:0004003=GO_REF:0000019, GO:0008104=PMID:17509950, GO:0045944=PMID:8692841, GO:0016032=Reactome:REACT_6256, GO:0016887=PMID:17466626, GO:0001666=GO_REF:0000019, GO:0042277=GO_REF:0000019, GO:0006917=PMID:16914395, GO:0005525=GO_REF:0000019, GO:0008022=PMID:10801852, GO:0005524=GO_REF:0000019, GO:0008353=PMID:9852112, GO:0003677=PMID:8663148, GO:0050434=Reactome:REACT_6162, GO:0003684=PMID:2167179, GO:0047485=PMID:8652557, GO:0004672=PMID:9852112, GO:0019048=GO_REF:0000037, GO:0006468=GO_REF:0000019, GO:0000717=PMID:17466626, GO:0000718=Reactome:REACT_311, GO:0005675=PMID:8692842, GO:0006265=PMID:8663148, GO:0033683=PMID:17466626} P19447 TFIIH basal transcription factor complex helicase XPB subunit protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0009650=IEA, GO:0006368=TAS, GO:0006367=TAS, GO:0006366=TAS, GO:0000441=IEA, GO:0006363=TAS, GO:0006362=TAS, GO:0006361=TAS, GO:0006360=TAS, GO:0009411=IMP, GO:0006979=IMP, GO:0008094=IDA, GO:0032564=IEA, GO:0006370=TAS, GO:0006281=TAS, GO:0006283=TAS, GO:0000075=IMP, GO:0043138=IDA, GO:0005654=TAS, GO:0006289=TAS, GO:0008134=IDA, GO:0035315=IMP, GO:0022415=TAS, GO:0005634=TAS, GO:0004003=IEA, GO:0008104=IMP, GO:0045944=IDA, GO:0016032=TAS, GO:0016887=IDA, GO:0001666=IEA, GO:0042277=IEA, GO:0006917=IDA, GO:0005525=IEA, GO:0008022=IPI, GO:0005524=IEA, GO:0008353=IDA, GO:0003677=TAS, GO:0050434=TAS, GO:0003684=NAS, GO:0047485=IPI, GO:0004672=IDA, GO:0019048=IEA, GO:0006468=IEA, GO:0000717=IMP, GO:0000718=TAS, GO:0005675=IDA, GO:0006265=IMP, GO:0033683=IMP} 7-methylguanosine mRNA capping, DNA repair, DNA topological change, UV protection, cell cycle checkpoint, gene expression, hair cell differentiation, induction of apoptosis, nucleotide-excision repair, nucleotide-excision repair, DNA damage removal, nucleotide-excision repair, DNA duplex unwinding, nucleotide-excision repair, DNA incision, positive regulation of transcription from RNA polymerase II promoter, positive regulation of viral transcription, protein localization, protein phosphorylation, response to UV, response to hypoxia, response to oxidative stress, termination of RNA polymerase I transcription, transcription elongation from RNA polymerase I promoter, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase I promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase I promoter, transcription initiation from RNA polymerase II promoter, transcription-coupled nucleotide-excision repair, viral reproduction, viral reproductive process, virus-host interaction SSL2-core TFIIH complex, holo TFIIH complex, nucleoplasm, nucleus 3'-5' DNA helicase activity, ATP binding, ATP-dependent DNA helicase activity, ATPase activity, DNA binding, DNA-dependent ATPase activity, GTP binding, RNA polymerase II carboxy-terminal domain kinase activity, dATP binding, damaged DNA binding, peptide binding, protein C-terminus binding, protein N-terminus binding, protein binding, protein kinase activity, transcription factor binding Human UniProtKB:Q01831 ERCC4 BHF-UCL UniProtKB {GO:0005515=PMID:14690602, GO:0009650=GO_REF:0000019, GO:0010834=PMID:17055345, GO:0000110=PMID:10413517, GO:0005634=PMID:12571280, GO:0000109=PMID:10644440, GO:0000723=PMID:14690602, GO:0006295=PMID:11790111, GO:0003697=PMID:10413517, GO:0000724=PMID:14728600, GO:0006296=PMID:14728600, GO:0009411=PMID:16678501, GO:0000784=PMID:14690602, GO:0000781=PMID:14690602, GO:0004520=PMID:14734547, GO:0008022=PMID:9722633, GO:0003684=PMID:11790111, GO:0006281=Reactome:REACT_216, GO:0047485=PMID:14734547, GO:0000710=GO_REF:0000033, GO:0006283=Reactome:REACT_1628, GO:0000712=GO_REF:0000033, GO:0043566=PMID:14734547, GO:0000014=GO_REF:0000033, GO:0032205=PMID:17055345, GO:0005654=Reactome:REACT_2163, GO:0006289=Reactome:REACT_1826, GO:0000718=Reactome:REACT_311, GO:0033683=PMID:10413517} Q92889 DNA repair endonuclease XPF protein 20081216 {GO:0005515=IPI, GO:0009650=IEA, GO:0010834=IMP, GO:0000110=IDA, GO:0005634=IDA, GO:0000109=IDA, GO:0000723=IMP, GO:0006295=IMP, GO:0003697=IDA, GO:0000724=IMP, GO:0006296=IMP, GO:0009411=IMP, GO:0000784=IDA, GO:0000781=IDA, GO:0004520=IDA, GO:0008022=IPI, GO:0003684=IMP, GO:0006281=TAS, GO:0047485=IPI, GO:0000710=IBA, GO:0006283=TAS, GO:0000712=IBA, GO:0043566=IDA, GO:0000014=IBA, GO:0032205=IMP, GO:0005654=TAS, GO:0006289=TAS, GO:0000718=TAS, GO:0033683=IDA} DNA repair, UV protection, double-strand break repair via homologous recombination, meiotic mismatch repair, negative regulation of telomere maintenance, nucleotide-excision repair, nucleotide-excision repair, DNA damage removal, nucleotide-excision repair, DNA incision, nucleotide-excision repair, DNA incision, 3'-to lesion, nucleotide-excision repair, DNA incision, 5'-to lesion, resolution of meiotic recombination intermediates, response to UV, telomere maintenance, telomere maintenance via telomere shortening, transcription-coupled nucleotide-excision repair chromosome, telomeric region, nuclear chromosome, telomeric region, nucleoplasm, nucleotide-excision repair complex, nucleotide-excision repair factor 1 complex, nucleus damaged DNA binding, endodeoxyribonuclease activity, protein C-terminus binding, protein N-terminus binding, protein binding, single-stranded DNA binding, single-stranded DNA specific endodeoxyribonuclease activity, structure-specific DNA binding Human ERCC5 InterPro UniProtKB {GO:0005515=PMID:8652557, GO:0009650=PMID:7510366, GO:0043066=PMID:16167068, GO:0000405=PMID:16246722, GO:0004520=PMID:12644470, GO:0005634=GO_REF:0000002, GO:0008340=GO_REF:0000019, GO:0042803=PMID:10026181, GO:0046872=GO_REF:0000037, GO:0010225=PMID:17208056, GO:0003690=PMID:8090225, GO:0047485=PMID:8652557, GO:0006281=Reactome:REACT_216, GO:0004519=GO_REF:0000002, GO:0006295=PMID:7657672, GO:0003697=GO_REF:0000002, GO:0035264=GO_REF:0000019, GO:0006283=Reactome:REACT_1628, GO:0016591=PMID:16246722, GO:0005654=Reactome:REACT_2163, GO:0006289=GO_REF:0000002, GO:0000718=Reactome:REACT_311, GO:0009411=PMID:16167068, GO:0005675=PMID:11259578} Q9HD60 Xeroderma pigmentosum complementation group G protein splice variant protein 20130413 {GO:0005515=IPI, GO:0009650=IGI, GO:0043066=IMP, GO:0000405=IDA, GO:0004520=IDA, GO:0005634=IEA, GO:0008340=IEA, GO:0042803=IPI, GO:0046872=IEA, GO:0010225=IMP, GO:0003690=IDA, GO:0047485=IPI, GO:0006281=TAS, GO:0004519=IEA, GO:0006295=IMP, GO:0003697=IEA, GO:0035264=IEA, GO:0006283=TAS, GO:0016591=IDA, GO:0005654=TAS, GO:0006289=IEA, GO:0000718=TAS, GO:0009411=IMP, GO:0005675=IDA} DNA repair, UV protection, determination of adult lifespan, multicellular organism growth, negative regulation of apoptotic process, nucleotide-excision repair, nucleotide-excision repair, DNA damage removal, nucleotide-excision repair, DNA incision, 3'-to lesion, response to UV, response to UV-C, transcription-coupled nucleotide-excision repair DNA-directed RNA polymerase II, holoenzyme, holo TFIIH complex, nucleoplasm, nucleus bubble DNA binding, double-stranded DNA binding, endodeoxyribonuclease activity, endonuclease activity, metal ion binding, protein N-terminus binding, protein binding, protein homodimerization activity, single-stranded DNA binding Human InterPro:IPR001044 ERCC6 IntAct UniProtKB {GO:0005515=PMID:7664335, GO:0010165=GO_REF:0000019, GO:0006366=PMID:7664335, GO:0005634=PMID:12560492, GO:0045494=GO_REF:0000019, GO:0032403=PMID:16916636, GO:0032786=PMID:9326587, GO:0006290=GO_REF:0000019, GO:0032784=PMID:9326587, GO:0006979=PMID:16107709, GO:0010332=GO_REF:0000019, GO:0009411=PMID:16916636, GO:0008094=PMID:12560492, GO:0008630=GO_REF:0000019, GO:0004386=GO_REF:0000002, GO:0005730=PMID:16107709, GO:0009636=GO_REF:0000019, GO:0007256=GO_REF:0000019, GO:0007257=GO_REF:0000019, GO:0008022=PMID:16246722, GO:0008023=PMID:9326587, GO:0003677=PMID:16107709, GO:0005524=PMID:12560492, GO:0003678=PMID:8999876, GO:0006281=Reactome:REACT_216, GO:0047485=PMID:7664335, GO:0010224=GO_REF:0000019, GO:0006283=Reactome:REACT_1628, GO:0003682=PMID:16916636, GO:0006284=PMID:9973627, GO:0000303=GO_REF:0000019, GO:0005654=Reactome:REACT_1584, GO:0006289=Reactome:REACT_1826} Q03468 DNA excision repair protein ERCC-6 protein 20130415 {GO:0005515=IPI, GO:0010165=IEA, GO:0006366=NAS, GO:0005634=IDA, GO:0045494=IEA, GO:0032403=IDA, GO:0032786=IDA, GO:0006290=IEA, GO:0032784=IDA, GO:0006979=IDA, GO:0010332=IEA, GO:0009411=IDA, GO:0008094=IDA, GO:0008630=IEA, GO:0004386=IEA, GO:0005730=IDA, GO:0009636=IEA, GO:0007256=IEA, GO:0007257=IEA, GO:0008022=IPI, GO:0008023=IDA, GO:0003677=IDA, GO:0005524=IDA, GO:0003678=IDA, GO:0006281=TAS, GO:0047485=IPI, GO:0010224=IEA, GO:0006283=TAS, GO:0003682=IDA, GO:0006284=IMP, GO:0000303=IEA, GO:0005654=TAS, GO:0006289=TAS} DNA repair, activation of JNKK activity, activation of JUN kinase activity, base-excision repair, intrinsic apoptotic signaling pathway in response to DNA damage, nucleotide-excision repair, photoreceptor cell maintenance, positive regulation of DNA-dependent transcription, elongation, pyrimidine dimer repair, regulation of DNA-dependent transcription, elongation, response to UV, response to UV-B, response to X-ray, response to gamma radiation, response to oxidative stress, response to superoxide, response to toxic substance, transcription from RNA polymerase II promoter, transcription-coupled nucleotide-excision repair nucleolus, nucleoplasm, nucleus, transcription elongation factor complex ATP binding, DNA binding, DNA helicase activity, DNA-dependent ATPase activity, chromatin binding, helicase activity, protein C-terminus binding, protein N-terminus binding, protein binding, protein complex binding Human UniProtKB:Q13216-1 ERCC6L IntAct UniProtKB {GO:0005515=PMID:23275563, GO:0000236=Reactome:REACT_682, GO:0000087=Reactome:REACT_910, GO:0000777=GO_REF:0000039, GO:0004386=GO_REF:0000037, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0005829=Reactome:REACT_150414, GO:0051301=GO_REF:0000037} Q2NKX8 DNA excision repair protein ERCC-6-like protein 20130415 {GO:0005515=IPI, GO:0000236=TAS, GO:0000087=TAS, GO:0000777=IEA, GO:0004386=IEA, GO:0000278=TAS, GO:0000090=TAS, GO:0005524=IEA, GO:0003677=IEA, GO:0005829=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, cell division, mitotic anaphase, mitotic cell cycle, mitotic prometaphase condensed chromosome kinetochore, cytosol ATP binding, DNA binding, helicase activity, protein binding Human UniProtKB:P42858 ERCC8 IntAct UniProtKB {GO:0000209=PMID:12732143, GO:0005515=PMID:10944529, GO:0004842=PMID:12732143, GO:0010165=GO_REF:0000019, GO:0005634=PMID:11782547, GO:0032403=PMID:16916636, GO:0016363=PMID:11782547, GO:0006974=PMID:11782547, GO:0003678=PMID:8999876, GO:0051865=PMID:12732143, GO:0043234=PMID:12732143, GO:0000109=PMID:12732143, GO:0006281=Reactome:REACT_216, GO:0006283=Reactome:REACT_1628, GO:0005654=Reactome:REACT_1584, GO:0043161=PMID:16751180, GO:0031464=PMID:12732143, GO:0006289=Reactome:REACT_1826, GO:0009411=PMID:12732143, GO:0006979=PMID:11782547, GO:0008094=PMID:8999876} Q13216 DNA excision repair protein ERCC-8 protein 20130415 {GO:0000209=IDA, GO:0005515=IPI, GO:0004842=IDA, GO:0010165=IEA, GO:0005634=IDA, GO:0032403=IDA, GO:0016363=IDA, GO:0006974=IDA, GO:0003678=IDA, GO:0051865=IDA, GO:0043234=IDA, GO:0000109=IDA, GO:0006281=TAS, GO:0006283=TAS, GO:0005654=TAS, GO:0043161=IDA, GO:0031464=IDA, GO:0006289=TAS, GO:0009411=IDA, GO:0006979=IDA, GO:0008094=IDA} DNA repair, nucleotide-excision repair, proteasomal ubiquitin-dependent protein catabolic process, protein autoubiquitination, protein polyubiquitination, response to DNA damage stimulus, response to UV, response to X-ray, response to oxidative stress, transcription-coupled nucleotide-excision repair Cul4A-RING ubiquitin ligase complex, nuclear matrix, nucleoplasm, nucleotide-excision repair complex, nucleus, protein complex DNA helicase activity, DNA-dependent ATPase activity, protein binding, protein complex binding, ubiquitin-protein ligase activity Human UniProtKB:Q9HCS7 EREG Reactome UniProtKB {GO:0005515=PMID:9419975, GO:0008284=GO_REF:0000024, GO:0005154=PMID:10681561, GO:0008285=GO_REF:0000024, GO:0019221=PMID:9419975, GO:0042700=GO_REF:0000024, GO:0050680=PMID:10681561, GO:0007267=PMID:14581411, GO:0043434=GO_REF:0000019, GO:0001819=GO_REF:0000024, GO:0001556=GO_REF:0000024, GO:0048146=PMID:12702554, GO:0005615=PMID:14581411, GO:0009653=PMID:9337852, GO:0007173=Reactome:REACT_9417, GO:0045860=PMID:14581411, GO:0009887=PMID:9337852, GO:0051781=GO_REF:0000037, GO:0048160=GO_REF:0000024, GO:0042108=PMID:10681561, GO:0045410=GO_REF:0000024, GO:0048011=Reactome:REACT_11061, GO:0051151=PMID:14581411, GO:0048015=Reactome:REACT_12464, GO:0045741=PMID:9990076, GO:0045740=PMID:9337852, GO:0005576=Reactome:REACT_147854, GO:0045840=GO_REF:0000024, GO:0001525=GO_REF:0000037, GO:0048661=PMID:9990076, GO:0043616=PMID:10681561, GO:0045089=GO_REF:0000024, GO:0008543=Reactome:REACT_9470, GO:0005887=PMID:9337852, GO:0030216=PMID:10681561, GO:0045087=Reactome:REACT_6802, GO:0001550=GO_REF:0000024, GO:0042060=PMID:12898511, GO:0009299=PMID:10681561, GO:0007143=GO_REF:0000024, GO:0045892=PMID:14581411, GO:0008083=GO_REF:0000037, GO:0030728=GO_REF:0000024, GO:0042327=PMID:9419975} O14944 Proepiregulin protein 20130301 {GO:0005515=IPI, GO:0008284=ISS, GO:0005154=TAS, GO:0008285=ISS, GO:0019221=IDA, GO:0042700=ISS, GO:0050680=TAS, GO:0007267=IDA, GO:0043434=IEA, GO:0001819=ISS, GO:0001556=ISS, GO:0048146=IDA, GO:0005615=IDA, GO:0009653=TAS, GO:0007173=TAS, GO:0045860=IDA, GO:0009887=TAS, GO:0051781=IEA, GO:0048160=ISS, GO:0042108=IDA, GO:0045410=ISS, GO:0048011=TAS, GO:0051151=IDA, GO:0048015=TAS, GO:0045741=ISS, GO:0045740=IDA, GO:0005576=TAS, GO:0045840=ISS, GO:0001525=IEA, GO:0048661=ISS, GO:0043616=IDA, GO:0045089=ISS, GO:0008543=TAS, GO:0005887=TAS, GO:0030216=TAS, GO:0045087=TAS, GO:0001550=ISS, GO:0042060=TAS, GO:0009299=IDA, GO:0007143=ISS, GO:0045892=IDA, GO:0008083=IEA, GO:0030728=ISS, GO:0042327=IDA} anatomical structure morphogenesis, angiogenesis, cell-cell signaling, cytokine-mediated signaling pathway, epidermal growth factor receptor signaling pathway, female meiosis, fibroblast growth factor receptor signaling pathway, innate immune response, keratinocyte differentiation, keratinocyte proliferation, luteinizing hormone signaling pathway, mRNA transcription, negative regulation of cell proliferation, negative regulation of epithelial cell proliferation, negative regulation of smooth muscle cell differentiation, negative regulation of transcription, DNA-dependent, neurotrophin TRK receptor signaling pathway, oocyte maturation, organ morphogenesis, ovarian cumulus expansion, ovulation, phosphatidylinositol-mediated signaling, positive regulation of DNA replication, positive regulation of cell division, positive regulation of cell proliferation, positive regulation of cytokine biosynthetic process, positive regulation of cytokine production, positive regulation of epidermal growth factor-activated receptor activity, positive regulation of fibroblast proliferation, positive regulation of innate immune response, positive regulation of interleukin-6 biosynthetic process, positive regulation of mitosis, positive regulation of phosphorylation, positive regulation of protein kinase activity, positive regulation of smooth muscle cell proliferation, primary follicle stage, response to peptide hormone stimulus, wound healing extracellular region, extracellular space, integral to plasma membrane epidermal growth factor receptor binding, growth factor activity, protein binding Human ERF UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0007049=PMID:7588608, GO:0060710=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0003714=PMID:7588608, GO:0060707=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0000122=PMID:7588608, GO:0010668=GO_REF:0000019, GO:0006351=GO_REF:0000037} P50548 ETS domain-containing transcription factor ERF protein 20120606 {GO:0043565=IEA, GO:0007049=NAS, GO:0060710=IEA, GO:0003700=IEA, GO:0003714=IDA, GO:0060707=IEA, GO:0005634=IEA, GO:0000122=IDA, GO:0010668=IEA, GO:0006351=IEA} cell cycle, chorio-allantoic fusion, ectodermal cell differentiation, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent, trophoblast giant cell differentiation nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human ERG IntAct UniProtKB {GO:0005515=PMID:21575865, GO:0003700=GO_REF:0000002, GO:0008283=PMID:3476934, GO:0005634=GO_REF:0000039, GO:0007275=PMID:8502479, GO:0003677=PMID:8502479, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0007165=PMID:8502479, GO:0005737=GO_REF:0000039, GO:0030529=PMID:17289661, GO:0006468=PMID:8502479, GO:0004871=PMID:8502479} P11308 Transcriptional regulator ERG protein 20130415 {GO:0005515=IPI, GO:0003700=IEA, GO:0008283=TAS, GO:0005634=IEA, GO:0007275=TAS, GO:0003677=TAS, GO:0006351=IEA, GO:0043565=IEA, GO:0007165=TAS, GO:0005737=IEA, GO:0030529=IDA, GO:0006468=TAS, GO:0004871=TAS} cell proliferation, multicellular organismal development, protein phosphorylation, signal transduction, transcription, DNA-dependent cytoplasm, nucleus, ribonucleoprotein complex DNA binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, signal transducer activity Human UniProtKB:P09874 ERGIC1 HGNC UniProtKB {GO:0005515=PMID:15308636, GO:0006888=PMID:15308636, GO:0005793=PMID:15308636, GO:0000139=GO_REF:0000039, GO:0033116=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q969X5 Endoplasmic reticulum-Golgi intermediate compartment protein 1 protein 20060104 {GO:0005515=IPI, GO:0006888=IDA, GO:0005793=IDA, GO:0000139=IEA, GO:0033116=IEA, GO:0005789=IEA, GO:0016021=IEA} ER to Golgi vesicle-mediated transport Golgi membrane, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment, endoplasmic reticulum-Golgi intermediate compartment membrane, integral to membrane protein binding Human UniProtKB:O95330 ERGIC2 UniProtKB UniProtKB {GO:0005794=GO_REF:0000039, GO:0033116=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0016192=GO_REF:0000037} Q96RQ1 Endoplasmic reticulum-Golgi intermediate compartment protein 2 protein 20130413 {GO:0005794=IEA, GO:0033116=IEA, GO:0005789=IEA, GO:0005634=IEA, GO:0016021=IEA, GO:0016192=IEA} vesicle-mediated transport Golgi apparatus, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment membrane, integral to membrane, nucleus Human UniProtKB-SubCell:SL-0099 ERGIC3 UniProtKB UniProtKB {GO:0005794=GO_REF:0000039, GO:0033116=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0016192=GO_REF:0000037} Q9Y282 Endoplasmic reticulum-Golgi intermediate compartment protein 3 protein 20130413 {GO:0005794=IEA, GO:0033116=IEA, GO:0005789=IEA, GO:0016021=IEA, GO:0016192=IEA} vesicle-mediated transport Golgi apparatus, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment membrane, integral to membrane Human UniProtKB-SubCell:SL-0099 ERH PINC UniProtKB {GO:0006213=PMID:8786099, GO:0006139=PMID:9074495, GO:0007049=GO_REF:0000037, GO:0030496=PMID:15166316} P84090 Enhancer of rudimentary homolog protein 20040715 {GO:0006213=TAS, GO:0006139=TAS, GO:0007049=IEA, GO:0030496=IDA} cell cycle, nucleobase-containing compound metabolic process, pyrimidine nucleoside metabolic process midbody Human ERI1 UniProtKB UniProtKB {GO:0005737=PMID:16912046, GO:0008408=PMID:16912046, GO:0071044=PMID:18172165, GO:0005730=PMID:16912046, GO:0043022=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0019843=GO_REF:0000024, GO:0071204=GO_REF:0000024, GO:0031047=GO_REF:0000037, GO:0071207=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0031125=GO_REF:0000024} Q8IV48 3'-5' exoribonuclease 1 protein 20090116 {GO:0005737=IDA, GO:0008408=IDA, GO:0071044=IMP, GO:0005730=IDA, GO:0043022=ISS, GO:0005634=ISS, GO:0019843=ISS, GO:0071204=ISS, GO:0031047=IEA, GO:0071207=ISS, GO:0046872=IEA, GO:0031125=ISS} gene silencing by RNA, histone mRNA catabolic process, rRNA 3'-end processing cytoplasm, histone pre-mRNA 3'end processing complex, nucleolus, nucleus 3'-5' exonuclease activity, histone pre-mRNA stem-loop binding, metal ion binding, rRNA binding, ribosome binding Human UniProtKB:Q7TMF2 ERI3 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0004527=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0046872=GO_REF:0000037} O43414 ERI1 exoribonuclease 3 protein 20130413 {GO:0005622=IEA, GO:0004527=IEA, GO:0003676=IEA, GO:0046872=IEA} intracellular exonuclease activity, metal ion binding, nucleic acid binding Human UniProtKB-KW:KW-0479 ERICH1 null null {} null null null null {} null null null ERLEC1 UniProtKB UniProtKB {GO:0005515=PMID:18502753, GO:0001948=PMID:16531414, GO:0005788=PMID:16531414} Q96DZ1 Endoplasmic reticulum lectin 1 protein 20120708 {GO:0005515=IPI, GO:0001948=IDA, GO:0005788=IDA} endoplasmic reticulum lumen glycoprotein binding, protein binding Human UniProtKB:Q13438 ERLIN1 HPA UniProtKB {GO:0005515=PMID:19240031, GO:0043234=PMID:18468998, GO:0005783=GO_REF:0000052, GO:0005789=PMID:16835267, GO:0016021=GO_REF:0000037, GO:0030433=PMID:19240031} O75477 Erlin-1 protein 20081203 {GO:0005515=IPI, GO:0043234=IDA, GO:0005783=IDA, GO:0005789=IDA, GO:0016021=IEA, GO:0030433=IDA} ER-associated protein catabolic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, protein complex protein binding Human ERLIN2 HPA UniProtKB {GO:0005515=PMID:19240031, GO:0043234=PMID:18468998, GO:0008219=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005783=GO_REF:0000052, GO:0005789=PMID:16835267, GO:0016021=GO_REF:0000037, GO:0030433=PMID:19240031} O94905 Erlin-2 protein 20101115 {GO:0005515=IPI, GO:0043234=IDA, GO:0008219=IEA, GO:0005737=IDA, GO:0005886=IDA, GO:0005783=IDA, GO:0005789=IDA, GO:0016021=IEA, GO:0030433=IDA} ER-associated protein catabolic process, cell death cytoplasm, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, plasma membrane, protein complex protein binding Human ERMAP MGI UniProtKB {GO:0005886=PMID:11549310, GO:0031410=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q96PL5 Erythroid membrane-associated protein protein 20040716 {GO:0005886=IDA, GO:0031410=IEA, GO:0016021=IEA} cytoplasmic vesicle, integral to membrane, plasma membrane Human ERMN UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0033269=GO_REF:0000019, GO:0031344=GO_REF:0000019, GO:0051015=GO_REF:0000019, GO:0043209=GO_REF:0000019, GO:0008360=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0033270=GO_REF:0000019, GO:0007015=GO_REF:0000019, GO:0030175=GO_REF:0000019, GO:0005856=GO_REF:0000039, GO:0001763=GO_REF:0000019} Q8TAM6 Ermin protein 20130413 {GO:0005737=IEA, GO:0033269=IEA, GO:0031344=IEA, GO:0051015=IEA, GO:0043209=IEA, GO:0008360=IEA, GO:0043025=IEA, GO:0033270=IEA, GO:0007015=IEA, GO:0030175=IEA, GO:0005856=IEA, GO:0001763=IEA} actin filament organization, morphogenesis of a branching structure, regulation of cell projection organization, regulation of cell shape cytoplasm, cytoskeleton, filopodium, internode region of axon, myelin sheath, neuronal cell body, paranode region of axon actin filament binding Human UniProtKB-SubCell:SL-0090 ERMP1 UniProtKB UniProtKB {GO:0005789=GO_REF:0000039, GO:0006508=GO_REF:0000037, GO:0008233=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0008237=GO_REF:0000037} Q7Z2K6 Endoplasmic reticulum metallopeptidase 1 protein 20130413 {GO:0005789=IEA, GO:0006508=IEA, GO:0008233=IEA, GO:0016021=IEA, GO:0046872=IEA, GO:0008237=IEA} proteolysis endoplasmic reticulum membrane, integral to membrane metal ion binding, metallopeptidase activity, peptidase activity Human UniProtKB-SubCell:SL-0097 ERN1 IntAct UniProtKB {GO:0005515=PMID:16645094, GO:0006397=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0000287=PMID:9637683, GO:0006915=GO_REF:0000037, GO:0005637=GO_REF:0000019, GO:0030176=PMID:9637683, GO:0004521=Reactome:REACT_22313, GO:0006917=GO_REF:0000024, GO:0005524=PMID:9637683, GO:0006351=GO_REF:0000037, GO:0030968=Reactome:REACT_18356, GO:0046777=GO_REF:0000019, GO:0004674=Reactome:REACT_18399, GO:0005789=Reactome:REACT_22313, GO:0007050=GO_REF:0000024, GO:0006468=PMID:9637683, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015} O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 protein 20130415 {GO:0005515=IPI, GO:0006397=IEA, GO:0006355=IEA, GO:0000287=IDA, GO:0006915=IEA, GO:0005637=IEA, GO:0030176=IDA, GO:0004521=TAS, GO:0006917=ISS, GO:0005524=IDA, GO:0006351=IEA, GO:0030968=TAS, GO:0046777=IEA, GO:0004674=TAS, GO:0005789=TAS, GO:0007050=ISS, GO:0006468=IDA, GO:0006987=TAS, GO:0044267=TAS} activation of signaling protein activity involved in unfolded protein response, apoptotic process, cell cycle arrest, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, induction of apoptosis, mRNA processing, protein autophosphorylation, protein phosphorylation, regulation of transcription, DNA-dependent, transcription, DNA-dependent endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane, nuclear inner membrane ATP binding, endoribonuclease activity, magnesium ion binding, protein binding, protein serine/threonine kinase activity Human UniProtKB:Q07813 ERO1L Reactome UniProtKB {GO:0034976=GO_REF:0000024, GO:0051209=GO_REF:0000024, GO:0005783=PMID:10671517, GO:0050660=GO_REF:0000002, GO:0003756=GO_REF:0000002, GO:0043231=PMID:10671517, GO:0030968=GO_REF:0000019, GO:0009266=PMID:10671517, GO:0016020=PMID:10671517, GO:0006457=PMID:10671517, GO:0050873=GO_REF:0000019, GO:0070059=GO_REF:0000024, GO:0016491=PMID:11707400, GO:0051085=PMID:11707400, GO:0005789=GO_REF:0000039, GO:0016671=GO_REF:0000002, GO:0005788=Reactome:REACT_15454, GO:0022900=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006464=PMID:10671517} Q96HE7 ERO1-like protein alpha protein 20130301 {GO:0034976=ISS, GO:0051209=ISS, GO:0005783=IDA, GO:0050660=IEA, GO:0003756=IEA, GO:0043231=TAS, GO:0030968=IEA, GO:0009266=TAS, GO:0016020=TAS, GO:0006457=TAS, GO:0050873=IEA, GO:0070059=ISS, GO:0016491=IDA, GO:0051085=IDA, GO:0005789=IEA, GO:0016671=IEA, GO:0005788=TAS, GO:0022900=IEA, GO:0044267=TAS, GO:0006464=TAS} brown fat cell differentiation, cellular protein metabolic process, cellular protein modification process, chaperone mediated protein folding requiring cofactor, electron transport chain, endoplasmic reticulum unfolded protein response, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, protein folding, release of sequestered calcium ion into cytosol, response to endoplasmic reticulum stress, response to temperature stimulus endoplasmic reticulum, endoplasmic reticulum lumen, endoplasmic reticulum membrane, intracellular membrane-bounded organelle, membrane flavin adenine dinucleotide binding, oxidoreductase activity, oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor, protein disulfide isomerase activity Human ERO1LB UniProtKB UniProtKB {GO:0006457=PMID:10818100, GO:0005783=PMID:10818100, GO:0050660=GO_REF:0000002, GO:0016491=PMID:10818100, GO:0016671=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0003756=GO_REF:0000002, GO:0051082=PMID:10818100, GO:0022900=GO_REF:0000037} Q86YB8 ERO1-like protein beta protein 20050308 {GO:0006457=TAS, GO:0005783=TAS, GO:0050660=IEA, GO:0016491=NAS, GO:0016671=IEA, GO:0005789=IEA, GO:0003756=IEA, GO:0051082=NAS, GO:0022900=IEA} electron transport chain, protein folding endoplasmic reticulum, endoplasmic reticulum membrane flavin adenine dinucleotide binding, oxidoreductase activity, oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor, protein disulfide isomerase activity, unfolded protein binding Human ERP27 UniProtKB UniProtKB {GO:0005788=GO_REF:0000039} Q96DN0 Endoplasmic reticulum resident protein 27 protein 20130413 {GO:0005788=IEA} endoplasmic reticulum lumen Human UniProtKB-SubCell:SL-0096 ERP29 PINC UniProtKB {GO:0042470=GO_REF:0000039, GO:0009306=GO_REF:0000002, GO:0009986=PMID:19995400, GO:0006457=PMID:9738895, GO:0005783=PMID:9738895, GO:0003756=PMID:9738895, GO:0005788=GO_REF:0000039, GO:0006886=PMID:9738895} P30040 Endoplasmic reticulum resident protein 29 protein 20030904 {GO:0042470=IEA, GO:0009306=IEA, GO:0009986=IDA, GO:0006457=TAS, GO:0005783=TAS, GO:0003756=TAS, GO:0005788=IEA, GO:0006886=TAS} intracellular protein transport, protein folding, protein secretion cell surface, endoplasmic reticulum, endoplasmic reticulum lumen, melanosome protein disulfide isomerase activity Human ERP44 MGI UniProtKB {GO:0006986=PMID:11847130, GO:0009100=PMID:11847130, GO:0005793=PMID:15308636, GO:0009986=PMID:19995400, GO:0006457=PMID:11847130, GO:0005789=PMID:11847130, GO:0006950=PMID:11847130, GO:0005788=PMID:11847130, GO:0003756=PMID:11847130, GO:0045454=PMID:11847130} Q9BS26 Endoplasmic reticulum resident protein 44 protein 20120926 {GO:0006986=IDA, GO:0009100=IDA, GO:0005793=IDA, GO:0009986=IDA, GO:0006457=IDA, GO:0005789=IDA, GO:0006950=IDA, GO:0005788=IDA, GO:0003756=IDA, GO:0045454=TAS} cell redox homeostasis, glycoprotein metabolic process, protein folding, response to stress, response to unfolded protein cell surface, endoplasmic reticulum lumen, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment protein disulfide isomerase activity Human ERRFI1 GOC UniProtKB {GO:0005515=PMID:21988832, GO:0060426=GO_REF:0000024, GO:0060428=GO_REF:0000024, GO:0048286=GO_REF:0000024, GO:0019901=PMID:18046415, GO:0006950=PMID:10749885, GO:0005634=GO_REF:0000039, GO:0005100=PMID:10749885, GO:0031234=GO_REF:0000024, GO:0031953=PMID:18046415, GO:0045616=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0032321=PMID:10749885, GO:0007175=PMID:18046415, GO:0043589=GO_REF:0000024} Q9UJM3 ERBB receptor feedback inhibitor 1 protein 20130413 {GO:0005515=IPI, GO:0060426=ISS, GO:0060428=ISS, GO:0048286=ISS, GO:0019901=IPI, GO:0006950=TAS, GO:0005634=IEA, GO:0005100=TAS, GO:0031234=ISS, GO:0031953=IDA, GO:0045616=ISS, GO:0005737=IDA, GO:0032321=TAS, GO:0007175=IDA, GO:0043589=ISS} lung alveolus development, lung epithelium development, lung vasculature development, negative regulation of epidermal growth factor-activated receptor activity, negative regulation of protein autophosphorylation, positive regulation of Rho GTPase activity, regulation of keratinocyte differentiation, response to stress, skin morphogenesis cytoplasm, extrinsic to internal side of plasma membrane, nucleus Rho GTPase activator activity, protein binding, protein kinase binding Human ESAM Reactome UniProtKB {GO:0005886=Reactome:REACT_12081, GO:0005912=GO_REF:0000039, GO:0007596=Reactome:REACT_604, GO:0005923=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0050900=Reactome:REACT_12051, GO:0007156=GO_REF:0000019} Q96AP7 Endothelial cell-selective adhesion molecule protein 20130301 {GO:0005886=TAS, GO:0005912=IEA, GO:0007596=TAS, GO:0005923=IEA, GO:0016021=IEA, GO:0050900=TAS, GO:0007156=IEA} blood coagulation, homophilic cell adhesion, leukocyte migration adherens junction, integral to membrane, plasma membrane, tight junction Human ESCO1 Reactome UniProtKB {GO:0000084=Reactome:REACT_899, GO:0016746=GO_REF:0000037, GO:0034421=PMID:21111234, GO:0005654=Reactome:REACT_150456, GO:0000278=Reactome:REACT_152, GO:0000785=PMID:19907496, GO:0006275=PMID:19907496, GO:0046872=GO_REF:0000037} Q5FWF5 N-acetyltransferase ESCO1 protein 20120913 {GO:0000084=TAS, GO:0016746=IEA, GO:0034421=IMP, GO:0005654=TAS, GO:0000278=TAS, GO:0000785=IDA, GO:0006275=IMP, GO:0046872=IEA} S phase of mitotic cell cycle, mitotic cell cycle, post-translational protein acetylation, regulation of DNA replication chromatin, nucleoplasm metal ion binding, transferase activity, transferring acyl groups Human ESCO2 Reactome UniProtKB {GO:0000084=Reactome:REACT_899, GO:0016746=GO_REF:0000037, GO:0034421=PMID:21111234, GO:0005654=Reactome:REACT_150456, GO:0000278=Reactome:REACT_152, GO:0000785=PMID:19907496, GO:0046872=GO_REF:0000037, GO:0006275=PMID:19907496} Q56NI9 N-acetyltransferase ESCO2 protein 20120913 {GO:0000084=TAS, GO:0016746=IEA, GO:0034421=IMP, GO:0005654=TAS, GO:0000278=TAS, GO:0000785=IDA, GO:0046872=IEA, GO:0006275=IMP} S phase of mitotic cell cycle, mitotic cell cycle, post-translational protein acetylation, regulation of DNA replication chromatin, nucleoplasm metal ion binding, transferase activity, transferring acyl groups Human ESD HPA UniProtKB {GO:0004091=PMID:3164702, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0046294=GO_REF:0000002, GO:0016023=GO_REF:0000029, GO:0005634=GO_REF:0000052, GO:0047374=GO_REF:0000003, GO:0018738=GO_REF:0000003} P10768 S-formylglutathione hydrolase protein 20110516 {GO:0004091=NAS, GO:0008150=ND, GO:0005737=IDA, GO:0005794=IDA, GO:0046294=IEA, GO:0016023=NAS, GO:0005634=IDA, GO:0047374=IEA, GO:0018738=IEA} biological_process, formaldehyde catabolic process Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, nucleus S-formylglutathione hydrolase activity, carboxylesterase activity, methylumbelliferyl-acetate deacetylase activity Human ESF1 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0005654=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q9H501 ESF1 homolog protein 20130413 {GO:0006355=IEA, GO:0005730=IEA, GO:0005654=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus, nucleoplasm Human UniProtKB-SubCell:SL-0188 ESM1 UniProtKB UniProtKB {GO:0005576=GO_REF:0000029, GO:0001525=PMID:11866539, GO:0008083=GO_REF:0000029, GO:0001558=GO_REF:0000002, GO:0005520=GO_REF:0000002} Q9NQ30 Endothelial cell-specific molecule 1 protein 20110330 {GO:0005576=NAS, GO:0001525=IEP, GO:0008083=NAS, GO:0001558=IEA, GO:0005520=IEA} angiogenesis, regulation of cell growth extracellular region growth factor activity, insulin-like growth factor binding Human ESPL1 Reactome UniProtKB {GO:0005515=PMID:12672959, GO:0005813=PMID:12672959, GO:0045842=PMID:12672959, GO:0006915=PMID:11875078, GO:0005634=GO_REF:0000039, GO:0003824=PMID:12672959, GO:0045875=PMID:12194817, GO:0000212=GO_REF:0000019, GO:0005829=Reactome:REACT_150369, GO:0000910=PMID:11509732, GO:0000070=PMID:12672959, GO:0045143=GO_REF:0000019, GO:0040001=PMID:12672959, GO:0000087=Reactome:REACT_910, GO:0006508=GO_REF:0000037, GO:0008233=GO_REF:0000019, GO:0008234=Reactome:REACT_150369, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} Q14674 Separin protein 20120913 {GO:0005515=IPI, GO:0005813=IDA, GO:0045842=NAS, GO:0006915=TAS, GO:0005634=IEA, GO:0003824=NAS, GO:0045875=NAS, GO:0000212=IEA, GO:0005829=TAS, GO:0000910=NAS, GO:0000070=IMP, GO:0045143=IEA, GO:0040001=NAS, GO:0000087=TAS, GO:0006508=IEA, GO:0008233=IEA, GO:0008234=TAS, GO:0000278=TAS, GO:0000090=TAS} M phase of mitotic cell cycle, apoptotic process, cytokinesis, establishment of mitotic spindle localization, homologous chromosome segregation, meiotic spindle organization, mitotic anaphase, mitotic cell cycle, mitotic sister chromatid segregation, negative regulation of sister chromatid cohesion, positive regulation of mitotic metaphase/anaphase transition, proteolysis centrosome, cytosol, nucleus catalytic activity, cysteine-type peptidase activity, peptidase activity, protein binding Human ESPN UniProtKB UniProtKB {GO:0005903=PMID:9763424, GO:0017124=PMID:12598619, GO:0005737=GO_REF:0000019, GO:0051015=PMID:8799813, GO:0031941=PMID:8799813, GO:0051494=GO_REF:0000019, GO:0030046=GO_REF:0000019, GO:0007605=GO_REF:0000037, GO:0032420=GO_REF:0000039, GO:0051491=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0032426=GO_REF:0000019} B1AK53 Espin protein 20091215 {GO:0005903=ISS, GO:0017124=ISS, GO:0005737=IEA, GO:0051015=ISS, GO:0031941=ISS, GO:0051494=IEA, GO:0030046=IEA, GO:0007605=IEA, GO:0032420=IEA, GO:0051491=IEA, GO:0007626=IEA, GO:0032426=IEA} locomotory behavior, negative regulation of cytoskeleton organization, parallel actin filament bundle assembly, positive regulation of filopodium assembly, sensory perception of sound brush border, cytoplasm, filamentous actin, stereocilium, stereocilium bundle tip SH3 domain binding, actin filament binding Human UniProtKB:Q63618 ESR1 UniProtKB UniProtKB {GO:0005515=PMID:17363140, GO:0010467=Reactome:REACT_71, GO:0043627=PMID:11581164, GO:0003700=GO_REF:0000002, GO:0006367=Reactome:REACT_15525, GO:0008013=PMID:15304487, GO:0060750=GO_REF:0000019, GO:0003707=PMID:11004670, GO:0042802=PMID:21182205, GO:0002064=GO_REF:0000019, GO:0004879=GO_REF:0000019, GO:0005496=GO_REF:0000002, GO:0032355=PMID:15304487, GO:0043124=PMID:16043358, GO:0005794=GO_REF:0000039, GO:0071391=GO_REF:0000019, GO:0060687=GO_REF:0000019, GO:0001547=GO_REF:0000019, GO:0048386=PMID:15831516, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_116083, GO:0019899=PMID:12039952, GO:0008134=GO_REF:0000019, GO:0060065=GO_REF:0000019, GO:0005886=PMID:15569929, GO:0060068=GO_REF:0000019, GO:0030284=GO_REF:0000002, GO:0005634=GO_REF:0000029, GO:0038052=PMID:18722177, GO:0048146=GO_REF:0000019, GO:0043433=PMID:10816575, GO:0034056=PMID:17975005, GO:0005737=GO_REF:0000019, GO:0051091=PMID:10681512, GO:0045944=GO_REF:0000019, GO:0060523=GO_REF:0000019, GO:0030235=PMID:12389206, GO:0060527=GO_REF:0000019, GO:0006355=GO_REF:0000029, GO:0060745=GO_REF:0000019, GO:0008209=GO_REF:0000019, GO:0042981=GO_REF:0000019, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000038, GO:0043565=GO_REF:0000002, GO:0007165=PMID:10749889, GO:0016020=PMID:11960618, GO:0003682=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0060749=GO_REF:0000019, GO:0008584=GO_REF:0000019, GO:0030520=PMID:3753802} Q9H2M1 Estrogen receptor alpha protein 20021106 {GO:0005515=IPI, GO:0010467=TAS, GO:0043627=IDA, GO:0003700=IEA, GO:0006367=TAS, GO:0008013=IPI, GO:0060750=IEA, GO:0003707=NAS, GO:0042802=IPI, GO:0002064=IEA, GO:0004879=IEA, GO:0005496=IEA, GO:0032355=IDA, GO:0043124=IDA, GO:0005794=IEA, GO:0071391=IEA, GO:0060687=IEA, GO:0001547=IEA, GO:0048386=IDA, GO:0008270=IEA, GO:0005654=TAS, GO:0019899=IPI, GO:0008134=IEA, GO:0060065=IEA, GO:0005886=IDA, GO:0060068=IEA, GO:0030284=IEA, GO:0005634=NAS, GO:0038052=IGI, GO:0048146=IEA, GO:0043433=IDA, GO:0034056=IDA, GO:0005737=IEA, GO:0051091=IDA, GO:0045944=IEA, GO:0060523=IEA, GO:0030235=NAS, GO:0060527=IEA, GO:0006355=NAS, GO:0060745=IEA, GO:0008209=IEA, GO:0042981=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0043565=IEA, GO:0007165=TAS, GO:0016020=NAS, GO:0003682=IEA, GO:0016021=IEA, GO:0060749=IEA, GO:0008584=IEA, GO:0030520=NAS} androgen metabolic process, antral ovarian follicle growth, cellular response to estrogen stimulus, epithelial cell development, epithelial cell proliferation involved in mammary gland duct elongation, gene expression, intracellular estrogen receptor signaling pathway, male gonad development, mammary gland alveolus development, mammary gland branching involved in pregnancy, negative regulation of I-kappaB kinase/NF-kappaB cascade, negative regulation of sequence-specific DNA binding transcription factor activity, positive regulation of fibroblast proliferation, positive regulation of retinoic acid receptor signaling pathway, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis, prostate epithelial cord elongation, regulation of apoptotic process, regulation of branching involved in prostate gland morphogenesis, regulation of transcription, DNA-dependent, response to estradiol stimulus, response to estrogen stimulus, signal transduction, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, uterus development, vagina development Golgi apparatus, cytoplasm, integral to membrane, membrane, nucleoplasm, nucleus, plasma membrane DNA binding, beta-catenin binding, chromatin binding, enzyme binding, estrogen receptor activity, estrogen response element binding, estrogen-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, identical protein binding, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, nitric-oxide synthase regulator activity, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid binding, steroid hormone receptor activity, transcription factor binding, zinc ion binding Human ESR2 GOC UniProtKB {GO:0005515=PMID:14764652, GO:0010467=Reactome:REACT_71, GO:0060065=GO_REF:0000019, GO:0030308=PMID:11181953, GO:0006367=Reactome:REACT_15525, GO:0003700=PMID:8769313, GO:0060068=GO_REF:0000019, GO:0007267=PMID:8769313, GO:0050680=GO_REF:0000019, GO:0003707=PMID:10749889, GO:0030284=PMID:11181953, GO:0005634=PMID:11181953, GO:0005739=PMID:15024130, GO:0001541=GO_REF:0000019, GO:0051091=PMID:10681512, GO:0004879=PMID:9671811, GO:0005496=PMID:11181953, GO:0048019=PMID:9671811, GO:0006355=PMID:11181953, GO:0043065=GO_REF:0000019, GO:0060743=GO_REF:0000019, GO:0003713=PMID:8769313, GO:0060740=GO_REF:0000019, GO:0060766=GO_REF:0000019, GO:0005576=PMID:9671811, GO:0003677=PMID:9636657, GO:0006351=GO_REF:0000038, GO:0043565=GO_REF:0000002, GO:0007165=PMID:8769313, GO:1900116=PMID:9671811, GO:0007420=GO_REF:0000019, GO:0005654=Reactome:REACT_19207, GO:0008270=GO_REF:0000002, GO:0001764=GO_REF:0000019, GO:0019899=PMID:12039952, GO:0030520=PMID:11181953} Q92731 Estrogen receptor beta protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0060065=IEA, GO:0030308=NAS, GO:0006367=TAS, GO:0003700=TAS, GO:0060068=IEA, GO:0007267=TAS, GO:0050680=IEA, GO:0003707=TAS, GO:0030284=TAS, GO:0005634=TAS, GO:0005739=IDA, GO:0001541=IEA, GO:0051091=IDA, GO:0004879=NAS, GO:0005496=TAS, GO:0048019=NAS, GO:0006355=TAS, GO:0043065=IEA, GO:0060743=IEA, GO:0003713=TAS, GO:0060740=IEA, GO:0060766=IEA, GO:0005576=NAS, GO:0003677=TAS, GO:0006351=IEA, GO:0043565=IEA, GO:0007165=TAS, GO:1900116=NAS, GO:0007420=IEA, GO:0005654=TAS, GO:0008270=IEA, GO:0001764=IEA, GO:0019899=IPI, GO:0030520=TAS} brain development, cell-cell signaling, epithelial cell maturation involved in prostate gland development, extracellular negative regulation of signal transduction, gene expression, intracellular estrogen receptor signaling pathway, negative regulation of androgen receptor signaling pathway, negative regulation of cell growth, negative regulation of epithelial cell proliferation, neuron migration, ovarian follicle development, positive regulation of apoptotic process, positive regulation of sequence-specific DNA binding transcription factor activity, prostate gland epithelium morphogenesis, regulation of transcription, DNA-dependent, signal transduction, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, uterus development, vagina development extracellular region, mitochondrion, nucleoplasm, nucleus DNA binding, enzyme binding, estrogen receptor activity, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, protein binding, receptor antagonist activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid binding, steroid hormone receptor activity, transcription coactivator activity, zinc ion binding Human ESRP1 HPA UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0005886=GO_REF:0000052, GO:0000166=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0043484=PMID:19285943, GO:0003729=PMID:19285943, GO:0003676=GO_REF:0000002} Q6NXG1 Epithelial splicing regulatory protein 1 protein 20100326 {GO:0008380=IEA, GO:0006397=IEA, GO:0005886=IDA, GO:0000166=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0043484=IDA, GO:0003729=IDA, GO:0003676=IEA} RNA splicing, mRNA processing, regulation of RNA splicing nucleolus, nucleus, plasma membrane mRNA binding, nucleic acid binding, nucleotide binding Human ESRP2 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0000166=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0043484=PMID:19285943, GO:0003729=PMID:19285943} Q9H6T0 Epithelial splicing regulatory protein 2 protein 20120912 {GO:0005739=IDA, GO:0008380=IEA, GO:0006397=IEA, GO:0005813=IDA, GO:0005737=IDA, GO:0000166=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0043484=IDA, GO:0003729=IDA} RNA splicing, mRNA processing, regulation of RNA splicing centrosome, cytoplasm, mitochondrion, nucleolus, nucleus mRNA binding, nucleotide binding Human ESRRA GOC UniProtKB {GO:0005515=PMID:16260778, GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_15525, GO:0003700=GO_REF:0000002, GO:0051216=GO_REF:0000019, GO:0019904=PMID:11984006, GO:0003707=GO_REF:0000002, GO:0005634=PMID:9286700, GO:0045670=GO_REF:0000019, GO:0003677=PMID:9286700, GO:0006351=GO_REF:0000038, GO:0043565=GO_REF:0000002, GO:0045667=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0045944=GO_REF:0000024, GO:0005654=Reactome:REACT_19207, GO:0008270=GO_REF:0000002, GO:0004879=PMID:9286700, GO:0030522=PMID:9286700, GO:0005496=GO_REF:0000002} P11474 Steroid hormone receptor ERR1 protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0006367=TAS, GO:0003700=IEA, GO:0051216=IEA, GO:0019904=IPI, GO:0003707=IEA, GO:0005634=TAS, GO:0045670=IEA, GO:0003677=TAS, GO:0006351=IEA, GO:0043565=IEA, GO:0045667=IEA, GO:0042127=IEA, GO:0045944=ISS, GO:0005654=TAS, GO:0008270=IEA, GO:0004879=TAS, GO:0030522=TAS, GO:0005496=IEA} cartilage development, gene expression, intracellular receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, regulation of cell proliferation, regulation of osteoblast differentiation, regulation of osteoclast differentiation, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent nucleoplasm, nucleus DNA binding, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, protein binding, protein domain specific binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid binding, steroid hormone receptor activity, zinc ion binding Human ESRRB GOC UniProtKB {GO:0010467=Reactome:REACT_71, GO:0001831=GO_REF:0000019, GO:0006367=Reactome:REACT_15525, GO:0003700=GO_REF:0000002, GO:0001834=GO_REF:0000019, GO:0003713=GO_REF:0000024, GO:0003707=GO_REF:0000002, GO:0001892=PMID:19196830, GO:0005634=GO_REF:0000024, GO:0006351=GO_REF:0000038, GO:0043565=PMID:12654265, GO:0045944=GO_REF:0000024, GO:0019827=GO_REF:0000019, GO:0000980=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_19207, GO:0004879=PMID:9344655, GO:0030522=PMID:9344655, GO:0005496=GO_REF:0000002, GO:0008134=GO_REF:0000024} O95718 Steroid hormone receptor ERR2 protein 20130413 {GO:0010467=TAS, GO:0001831=IEA, GO:0006367=TAS, GO:0003700=IEA, GO:0001834=IEA, GO:0003713=ISS, GO:0003707=IEA, GO:0001892=NAS, GO:0005634=ISS, GO:0006351=IEA, GO:0043565=IDA, GO:0045944=ISS, GO:0019827=IEA, GO:0000980=ISS, GO:0008270=IEA, GO:0005654=TAS, GO:0004879=TAS, GO:0030522=TAS, GO:0005496=IEA, GO:0008134=ISS} embryonic placenta development, gene expression, intracellular receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, stem cell maintenance, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, trophectodermal cell proliferation, trophectodermal cellular morphogenesis nucleoplasm, nucleus RNA polymerase II distal enhancer sequence-specific DNA binding, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid binding, steroid hormone receptor activity, transcription coactivator activity, transcription factor binding, zinc ion binding Human ESRRG Reactome UniProtKB {GO:0005515=PMID:10428842, GO:0010467=Reactome:REACT_71, GO:0003700=GO_REF:0000002, GO:0006367=Reactome:REACT_15525, GO:0003707=GO_REF:0000002, GO:0005634=GO_REF:0000038, GO:0050682=GO_REF:0000024, GO:0003708=GO_REF:0000002, GO:0006351=GO_REF:0000038, GO:0043565=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_19207, GO:0045893=GO_REF:0000024, GO:0005496=GO_REF:0000002} P62508 Estrogen-related receptor gamma protein 20130301 {GO:0005515=IPI, GO:0010467=TAS, GO:0003700=IEA, GO:0006367=TAS, GO:0003707=IEA, GO:0005634=IEA, GO:0050682=ISS, GO:0003708=IEA, GO:0006351=IEA, GO:0043565=IEA, GO:0008270=IEA, GO:0005654=TAS, GO:0045893=ISS, GO:0005496=IEA} gene expression, positive regulation of transcription, DNA-dependent, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent nucleoplasm, nucleus AF-2 domain binding, protein binding, retinoic acid receptor activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid binding, steroid hormone receptor activity, zinc ion binding Human ESX1 UniProtKB UniProtKB {GO:0043565=PMID:15897875, GO:0005737=PMID:15235584, GO:0003700=GO_REF:0000002, GO:0051726=PMID:15235584, GO:0005634=PMID:15235584, GO:0045892=PMID:15897875, GO:0006351=GO_REF:0000037} Q8N693 Homeobox protein ESX1 protein 20090924 {GO:0043565=IDA, GO:0005737=IDA, GO:0003700=IEA, GO:0051726=IDA, GO:0005634=IDA, GO:0045892=IDA, GO:0006351=IEA} negative regulation of transcription, DNA-dependent, regulation of cell cycle, transcription, DNA-dependent cytoplasm, nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human ESYT1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9BSJ8 Extended synaptotagmin-1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 ESYT2 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037} A0FGR8 Extended synaptotagmin-2 protein 20130413 {GO:0005886=IEA, GO:0016021=IEA} integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 ETAA1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9NY74 Ewing's tumor-associated antigen 1 protein 20101115 {GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA} cytoplasm, nucleolus, nucleus Human ETF1 InterPro UniProtKB {GO:0005515=PMID:9712840, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=PMID:7990965, GO:0006449=PMID:7990965, GO:0006415=Reactome:REACT_1986, GO:0003747=PMID:15326224, GO:0006412=Reactome:REACT_1014, GO:0005829=Reactome:REACT_75917, GO:0005737=GO_REF:0000002, GO:0016149=GO_REF:0000002, GO:0000184=Reactome:REACT_75886, GO:0006479=PMID:18539146, GO:0043022=PMID:12867083, GO:0008079=PMID:10413110, GO:0044267=Reactome:REACT_17015} Q96CG1 Eukaryotic translation termination factor 1, isoform CRA_b protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=TAS, GO:0006449=TAS, GO:0006415=TAS, GO:0003747=TAS, GO:0006412=TAS, GO:0005829=TAS, GO:0005737=IEA, GO:0016149=IEA, GO:0000184=TAS, GO:0006479=IDA, GO:0043022=TAS, GO:0008079=TAS, GO:0044267=TAS} RNA metabolic process, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, protein methylation, regulation of translational termination, translation, translational termination cytoplasm, cytosol RNA binding, protein binding, ribosome binding, translation release factor activity, translation release factor activity, codon specific, translation termination factor activity Human InterPro:IPR004403 ETFA Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005739=PMID:3170610, GO:0005759=Reactome:REACT_6169, GO:0050660=PMID:10423253, GO:0016491=PMID:10423253, GO:0009055=PMID:10423253, GO:0044281=Reactome:REACT_111217} P13804 Electron transfer flavoprotein subunit alpha, mitochondrial protein 20051125 {GO:0022904=TAS, GO:0005739=TAS, GO:0005759=TAS, GO:0050660=IDA, GO:0016491=IDA, GO:0009055=IDA, GO:0044281=TAS} respiratory electron transport chain, small molecule metabolic process mitochondrial matrix, mitochondrion electron carrier activity, flavin adenine dinucleotide binding, oxidoreductase activity Human ETFB HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0022904=Reactome:REACT_22393, GO:0005759=Reactome:REACT_6169, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0043231=GO_REF:0000052} P38117 Electron transfer flavoprotein subunit beta protein 20100326 {GO:0005739=IDA, GO:0022904=TAS, GO:0005759=TAS, GO:0009055=IEA, GO:0044281=TAS, GO:0043231=IDA} respiratory electron transport chain, small molecule metabolic process intracellular membrane-bounded organelle, mitochondrial matrix, mitochondrion electron carrier activity Human ETFDH BHF-UCL UniProtKB {GO:0048039=PMID:14640977, GO:0051539=PMID:18037314, GO:0048038=PMID:14640977, GO:0031966=PMID:12049629, GO:0051536=GO_REF:0000002, GO:0043783=GO_REF:0000024, GO:0050660=PMID:17050691, GO:0005743=GO_REF:0000019, GO:0009055=PMID:12049629, GO:0044281=Reactome:REACT_111217, GO:0033539=PMID:17412732, GO:0046872=GO_REF:0000037, GO:0022904=Reactome:REACT_22393, GO:0004174=PMID:12049629, GO:0005759=Reactome:REACT_6169, GO:0016491=PMID:14640977, GO:0031305=PMID:8306995, GO:0022900=PMID:12049629, GO:0006979=GO_REF:0000024} Q16134 Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial protein 20090907 {GO:0048039=IDA, GO:0051539=IDA, GO:0048038=IDA, GO:0031966=IDA, GO:0051536=IEA, GO:0043783=ISS, GO:0050660=ISS, GO:0005743=IEA, GO:0009055=IDA, GO:0044281=TAS, GO:0033539=IMP, GO:0046872=IEA, GO:0022904=TAS, GO:0004174=IDA, GO:0005759=TAS, GO:0016491=IDA, GO:0031305=IDA, GO:0022900=IDA, GO:0006979=ISS} electron transport chain, fatty acid beta-oxidation using acyl-CoA dehydrogenase, respiratory electron transport chain, response to oxidative stress, small molecule metabolic process integral to mitochondrial inner membrane, mitochondrial inner membrane, mitochondrial matrix, mitochondrial membrane 4 iron, 4 sulfur cluster binding, electron carrier activity, electron-transferring-flavoprotein dehydrogenase activity, flavin adenine dinucleotide binding, iron-sulfur cluster binding, metal ion binding, oxidoreductase activity, oxidoreductase activity, oxidizing metal ions with flavin as acceptor, quinone binding, ubiquinone binding Human ETHE1 HPA UniProtKB {GO:0050313=Reactome:REACT_115730, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0005739=GO_REF:0000052, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000054, GO:0000096=Reactome:REACT_115639, GO:0016787=GO_REF:0000037, GO:0000098=Reactome:REACT_115654, GO:0005759=Reactome:REACT_115730, GO:0070221=Reactome:REACT_116010} O95571 Protein ETHE1, mitochondrial protein 20111111 {GO:0050313=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0046872=IEA, GO:0005739=IDA, GO:0034641=TAS, GO:0005737=IDA, GO:0000096=TAS, GO:0016787=IEA, GO:0000098=TAS, GO:0005759=TAS, GO:0070221=TAS} cellular nitrogen compound metabolic process, small molecule metabolic process, sulfide oxidation, using sulfide:quinone oxidoreductase, sulfur amino acid catabolic process, sulfur amino acid metabolic process cytoplasm, mitochondrial matrix, mitochondrion, nucleolus, nucleus hydrolase activity, metal ion binding, sulfur dioxygenase activity Human ETNK1 Reactome UniProtKB {GO:0004305=PMID:11044454, GO:0006646=Reactome:REACT_120919, GO:0005737=GO_REF:0000029, GO:0016301=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0006644=Reactome:REACT_120870, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_121273, GO:0046474=Reactome:REACT_121401} Q9HBU6 Ethanolamine kinase 1 protein 20130301 {GO:0004305=IDA, GO:0006646=TAS, GO:0005737=NAS, GO:0016301=IEA, GO:0044281=TAS, GO:0006644=TAS, GO:0005524=IEA, GO:0005829=TAS, GO:0046474=TAS} glycerophospholipid biosynthetic process, phosphatidylethanolamine biosynthetic process, phospholipid metabolic process, small molecule metabolic process cytoplasm, cytosol ATP binding, ethanolamine kinase activity, kinase activity Human ETNK2 Reactome UniProtKB {GO:0004305=GO_REF:0000003, GO:0006646=Reactome:REACT_120919, GO:0044281=Reactome:REACT_111217, GO:0001890=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0009791=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_121273, GO:0008150=GO_REF:0000015, GO:0035264=GO_REF:0000019, GO:0016301=GO_REF:0000002, GO:0006644=Reactome:REACT_120870, GO:0046474=Reactome:REACT_121401} Q9NVF9 Ethanolamine kinase 2 protein 20130301 {GO:0004305=IEA, GO:0006646=TAS, GO:0044281=TAS, GO:0001890=IEA, GO:0005575=ND, GO:0009791=IEA, GO:0001701=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0008150=ND, GO:0035264=IEA, GO:0016301=IEA, GO:0006644=TAS, GO:0046474=TAS} biological_process, glycerophospholipid biosynthetic process, in utero embryonic development, multicellular organism growth, phosphatidylethanolamine biosynthetic process, phospholipid metabolic process, placenta development, post-embryonic development, small molecule metabolic process cellular_component, cytosol ATP binding, ethanolamine kinase activity, kinase activity Human ETS1 InterPro UniProtKB {GO:0005515=PMID:11909962, GO:0008284=GO_REF:0000019, GO:0003700=PMID:11909962, GO:0008285=PMID:2187191, GO:0070301=GO_REF:0000019, GO:0021983=GO_REF:0000019, GO:0005634=GO_REF:0000002, GO:0060206=GO_REF:0000019, GO:0010715=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0006955=PMID:2187191, GO:0030578=PMID:11909962, GO:0048870=PMID:15247905, GO:0045944=PMID:15247905, GO:0032355=GO_REF:0000019, GO:0070555=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:0060055=GO_REF:0000019, GO:0045765=PMID:15592518, GO:0021854=GO_REF:0000019, GO:0003677=GO_REF:0000024, GO:0045766=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0009612=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0010595=PMID:15592518, GO:0045648=PMID:8620536, GO:0034616=GO_REF:0000019, GO:0045893=PMID:11909962, GO:0051272=PMID:15247905, GO:0008134=PMID:10698492} Q96AC5 Protein C-ets-1 protein 20130413 {GO:0005515=IPI, GO:0008284=IEA, GO:0003700=IDA, GO:0008285=TAS, GO:0070301=IEA, GO:0021983=IEA, GO:0005634=IEA, GO:0060206=IEA, GO:0010715=IEA, GO:0005737=IEA, GO:0006955=TAS, GO:0030578=IDA, GO:0048870=IMP, GO:0045944=IDA, GO:0032355=IEA, GO:0070555=IEA, GO:0005667=IEA, GO:0001666=IEA, GO:0007565=IEA, GO:0060055=IEA, GO:0045765=IMP, GO:0021854=IEA, GO:0003677=ISS, GO:0045766=IEA, GO:0006351=IEA, GO:0009612=IEA, GO:0043565=IEA, GO:0010595=IMP, GO:0045648=IDA, GO:0034616=IEA, GO:0045893=IDA, GO:0051272=IMP, GO:0008134=NAS} PML body organization, angiogenesis involved in wound healing, cell motility, cellular response to hydrogen peroxide, estrous cycle phase, female pregnancy, hypothalamus development, immune response, negative regulation of cell proliferation, pituitary gland development, positive regulation of angiogenesis, positive regulation of cell proliferation, positive regulation of cellular component movement, positive regulation of endothelial cell migration, positive regulation of erythrocyte differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of angiogenesis, regulation of extracellular matrix disassembly, response to estradiol stimulus, response to hypoxia, response to interleukin-1, response to laminar fluid shear stress, response to mechanical stimulus, transcription, DNA-dependent cytoplasm, nucleus, transcription factor complex DNA binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human InterPro:IPR003118 ETS2 BHF-UCL UniProtKB {GO:0005515=PMID:11909962, GO:0001501=PMID:8596630, GO:0003700=PMID:11909962, GO:0000977=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0005634=PMID:16780588, GO:0035259=GO_REF:0000019, GO:0045893=PMID:11909962, GO:0003677=PMID:10918595} P15036 Protein C-ets-2 protein 20081024 {GO:0005515=IPI, GO:0001501=TAS, GO:0003700=IDA, GO:0000977=IEA, GO:0045944=IEA, GO:0005634=IDA, GO:0035259=IEA, GO:0045893=IDA, GO:0003677=TAS} positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, skeletal system development nucleus DNA binding, RNA polymerase II regulatory region sequence-specific DNA binding, glucocorticoid receptor binding, protein binding, sequence-specific DNA binding transcription factor activity Human ETV1 BHF-UCL UniProtKB {GO:0005515=PMID:21575865, GO:0043565=GO_REF:0000002, GO:0007517=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0006366=PMID:7700648, GO:0007411=GO_REF:0000019, GO:0048935=PMID:20096094, GO:0005634=GO_REF:0000039, GO:0007638=GO_REF:0000019, GO:0045893=GO_REF:0000019} P50549 ETS translocation variant 1 protein 20110708 {GO:0005515=IPI, GO:0043565=IEA, GO:0007517=IEA, GO:0003700=IEA, GO:0006366=TAS, GO:0007411=IEA, GO:0048935=TAS, GO:0005634=IEA, GO:0007638=IEA, GO:0045893=IEA} axon guidance, mechanosensory behavior, muscle organ development, peripheral nervous system neuron development, positive regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human ETV2 UniProtKB UniProtKB {GO:0003700=GO_REF:0000002, GO:2000382=GO_REF:0000019, GO:0001824=GO_REF:0000019, GO:0048514=GO_REF:0000019, GO:0006915=GO_REF:0000019, GO:0005634=GO_REF:0000038, GO:0001890=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0007219=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0030218=GO_REF:0000019, GO:0060803=GO_REF:0000019, GO:0016055=GO_REF:0000019, GO:0045603=GO_REF:0000019} Q3KNT2 ETS translocation variant 2 protein 20130413 {GO:0003700=IEA, GO:2000382=IEA, GO:0001824=IEA, GO:0048514=IEA, GO:0006915=IEA, GO:0005634=IEA, GO:0001890=IEA, GO:0043565=IEA, GO:0007219=IEA, GO:0045944=IEA, GO:0030218=IEA, GO:0060803=IEA, GO:0016055=IEA, GO:0045603=IEA} BMP signaling pathway involved in mesodermal cell fate specification, Notch signaling pathway, Wnt receptor signaling pathway, apoptotic process, blastocyst development, blood vessel morphogenesis, erythrocyte differentiation, placenta development, positive regulation of endothelial cell differentiation, positive regulation of mesoderm development, positive regulation of transcription from RNA polymerase II promoter nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-KW:KW-0539 ETV3 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0003700=GO_REF:0000002, GO:0017053=GO_REF:0000019, GO:0005634=GO_REF:0000029, GO:0000122=GO_REF:0000019, GO:0006351=GO_REF:0000037} P41162 ETS translocation variant 3 protein 20061026 {GO:0043565=IEA, GO:0003674=ND, GO:0008150=ND, GO:0003700=IEA, GO:0017053=IEA, GO:0005634=NAS, GO:0000122=IEA, GO:0006351=IEA} biological_process, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus, transcriptional repressor complex molecular_function, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human ETV4 HPA UniProtKB {GO:0048863=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0006355=GO_REF:0000029, GO:0008045=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0060762=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000029, GO:0045893=GO_REF:0000029, GO:0033600=GO_REF:0000019, GO:0060444=GO_REF:0000019, GO:0006351=GO_REF:0000037} P43268 ETS translocation variant 4 protein 20080818 {GO:0048863=IEA, GO:0043565=IEA, GO:0006355=NAS, GO:0008045=IEA, GO:0003700=IEA, GO:0060762=IEA, GO:0005730=IDA, GO:0005634=NAS, GO:0045893=NAS, GO:0033600=IEA, GO:0060444=IEA, GO:0006351=IEA} branching involved in mammary gland duct morphogenesis, motor neuron axon guidance, negative regulation of mammary gland epithelial cell proliferation, positive regulation of transcription, DNA-dependent, regulation of branching involved in mammary gland duct morphogenesis, regulation of transcription, DNA-dependent, stem cell differentiation, transcription, DNA-dependent nucleolus, nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human ETV5 PINC UniProtKB {GO:0003700=GO_REF:0000002, GO:0044212=PMID:19443906, GO:0060762=GO_REF:0000019, GO:0005634=PMID:19443906, GO:0007274=GO_REF:0000019, GO:0048133=GO_REF:0000019, GO:0060252=GO_REF:0000019, GO:0003677=PMID:8152800, GO:0043565=GO_REF:0000002, GO:0045666=GO_REF:0000019, GO:0050807=GO_REF:0000019, GO:0007610=GO_REF:0000019, GO:0034599=PMID:19443906, GO:0045893=GO_REF:0000019, GO:0071340=GO_REF:0000019} P41161 ETS translocation variant 5 protein 20030904 {GO:0003700=IEA, GO:0044212=IDA, GO:0060762=IEA, GO:0005634=IDA, GO:0007274=IEA, GO:0048133=IEA, GO:0060252=IEA, GO:0003677=TAS, GO:0043565=IEA, GO:0045666=IEA, GO:0050807=IEA, GO:0007610=IEA, GO:0034599=IDA, GO:0045893=IEA, GO:0071340=IEA} behavior, cellular response to oxidative stress, male germ-line stem cell division, neuromuscular synaptic transmission, positive regulation of glial cell proliferation, positive regulation of neuron differentiation, positive regulation of transcription, DNA-dependent, regulation of branching involved in mammary gland duct morphogenesis, regulation of synapse organization, skeletal muscle acetylcholine-gated channel clustering nucleus DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding Human ETV6 IntAct UniProtKB {GO:0005515=PMID:12590135, GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000019, GO:0019904=PMID:12588862, GO:0005634=GO_REF:0000039, GO:0030154=GO_REF:0000019, GO:0006351=GO_REF:0000037} P41212 Transcription factor ETV6 protein 20130415 {GO:0005515=IPI, GO:0043565=IEA, GO:0003700=IEA, GO:0019904=IPI, GO:0005634=IEA, GO:0030154=IEA, GO:0006351=IEA} cell differentiation, transcription, DNA-dependent nucleus protein binding, protein domain specific binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:Q9UKV0-3 ETV7 HPA UniProtKB {GO:0005515=PMID:12588862, GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0006366=PMID:10828014, GO:0005730=GO_REF:0000052, GO:0009887=PMID:10828014, GO:0005634=GO_REF:0000052} Q9Y603 Transcription factor ETV7 protein 20101115 {GO:0005515=IPI, GO:0043565=IEA, GO:0003700=IEA, GO:0006366=TAS, GO:0005730=IDA, GO:0009887=TAS, GO:0005634=IDA} organ morphogenesis, transcription from RNA polymerase II promoter nucleolus, nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity NOT Human EVC2 UniProtKB UniProtKB {GO:0005929=GO_REF:0000024, GO:0060170=GO_REF:0000039, GO:0005737=GO_REF:0000037, GO:0005634=GO_REF:0000024, GO:0005932=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0007224=GO_REF:0000024} Q86UK5 Limbin protein 20111004 {GO:0005929=ISS, GO:0060170=IEA, GO:0005737=IEA, GO:0005634=ISS, GO:0005932=IEA, GO:0016021=IEA, GO:0007224=ISS} smoothened signaling pathway cilium, cilium membrane, cytoplasm, integral to membrane, microtubule basal body, nucleus Human UniProtKB:Q8K1G2 EVI2A UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0004888=PMID:2117566} P22794 Protein EVI2A protein 20041028 {GO:0016021=IEA, GO:0004888=NAS} integral to membrane transmembrane signaling receptor activity Human EVI5 IntAct UniProtKB {GO:0005515=PMID:16439210, GO:0005622=GO_REF:0000002, GO:0007049=GO_REF:0000037, GO:0005737=GO_REF:0000037, GO:0005815=GO_REF:0000039, GO:0008283=PMID:9618176, GO:0005819=GO_REF:0000039, GO:0007275=PMID:9618176, GO:0005634=GO_REF:0000039, GO:0005097=GO_REF:0000002, GO:0051301=GO_REF:0000037} O60447 Ecotropic viral integration site 5 protein homolog protein 20130415 {GO:0005515=IPI, GO:0005622=IEA, GO:0007049=IEA, GO:0005737=IEA, GO:0005815=IEA, GO:0008283=TAS, GO:0005819=IEA, GO:0007275=TAS, GO:0005634=IEA, GO:0005097=IEA, GO:0051301=IEA} cell cycle, cell division, cell proliferation, multicellular organismal development cytoplasm, intracellular, microtubule organizing center, nucleus, spindle Rab GTPase activator activity, protein binding Human UniProtKB:Q9UKT4 EVI5L IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0005622=GO_REF:0000002, GO:0005097=GO_REF:0000002} Q96CN4 EVI5-like protein protein 20130415 {GO:0005515=IPI, GO:0005622=IEA, GO:0005097=IEA} intracellular Rab GTPase activator activity, protein binding Human UniProtKB:Q6ZVK8 EVL Reactome UniProtKB {GO:0005515=PMID:10993894, GO:0017124=GO_REF:0000024, GO:0003779=GO_REF:0000037, GO:0030027=GO_REF:0000024, GO:0005829=Reactome:REACT_19293, GO:0007399=PMID:10993894, GO:0005737=GO_REF:0000024, GO:0007411=Reactome:REACT_18266, GO:0051289=GO_REF:0000002, GO:0008154=GO_REF:0000024, GO:0009887=PMID:10993894, GO:0007015=PMID:9268706, GO:0005856=GO_REF:0000039, GO:0005522=GO_REF:0000024, GO:0005925=GO_REF:0000024, GO:0007166=PMID:10993894} Q9UI08 Ena/VASP-like protein protein 20130301 {GO:0005515=IPI, GO:0017124=ISS, GO:0003779=IEA, GO:0030027=ISS, GO:0005829=TAS, GO:0007399=NAS, GO:0005737=ISS, GO:0007411=TAS, GO:0051289=IEA, GO:0008154=ISS, GO:0009887=NAS, GO:0007015=TAS, GO:0005856=IEA, GO:0005522=ISS, GO:0005925=ISS, GO:0007166=NAS} actin filament organization, actin polymerization or depolymerization, axon guidance, cell surface receptor signaling pathway, nervous system development, organ morphogenesis, protein homotetramerization cytoplasm, cytoskeleton, cytosol, focal adhesion, lamellipodium SH3 domain binding, actin binding, profilin binding, protein binding Human EVPL PINC UniProtKB {GO:0030057=GO_REF:0000039, GO:0005737=GO_REF:0000037, GO:0018149=PMID:10908733, GO:0008544=PMID:8707850, GO:0030216=PMID:10908733, GO:0005198=PMID:10908733, GO:0031424=GO_REF:0000037, GO:0030674=PMID:10908733, GO:0005856=GO_REF:0000002, GO:0001533=PMID:10908733} Q92817 Envoplakin protein 20030904 {GO:0030057=IEA, GO:0005737=IEA, GO:0018149=IDA, GO:0008544=TAS, GO:0030216=IDA, GO:0005198=IDA, GO:0031424=IEA, GO:0030674=IDA, GO:0005856=IEA, GO:0001533=IDA} epidermis development, keratinization, keratinocyte differentiation, peptide cross-linking cornified envelope, cytoplasm, cytoskeleton, desmosome protein binding, bridging, structural molecule activity Human EVX1 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0045944=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0009792=GO_REF:0000019, GO:0021913=GO_REF:0000019} P49640 Homeobox even-skipped homolog protein 1 protein 20130413 {GO:0043565=IEA, GO:0003700=IEA, GO:0045944=IEA, GO:0005634=IEA, GO:0009792=IEA, GO:0021913=IEA} embryo development ending in birth or egg hatching, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0191 EWSR1 IntAct UniProtKB {GO:0005515=PMID:18347058, GO:0005622=GO_REF:0000002, GO:0005516=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0006355=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q01844 RNA-binding protein EWS protein 20130415 {GO:0005515=IPI, GO:0005622=IEA, GO:0005516=IEA, GO:0005737=IEA, GO:0006355=IEA, GO:0005886=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, intracellular, nucleus, plasma membrane RNA binding, calmodulin binding, nucleic acid binding, nucleotide binding, protein binding, zinc ion binding Human UniProtKB:Q9NS23-2 EXD1 InterPro UniProtKB {GO:0008408=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q8NHP7 Exonuclease 3'-5' domain-containing protein 1 protein 20130413 {GO:0008408=IEA, GO:0003676=IEA} 3'-5' exonuclease activity, nucleic acid binding Human InterPro:IPR002562 EXD2 InterPro UniProtKB {GO:0008408=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q9NVH0 Exonuclease 3'-5' domain-containing protein 2 protein 20130413 {GO:0008408=IEA, GO:0003676=IEA} 3'-5' exonuclease activity, nucleic acid binding Human InterPro:IPR002562 EXD3 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0008408=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q9NX53 Probable exonuclease mut-7 homolog, isoform 5 protein 20130415 {GO:0005515=IPI, GO:0008408=IEA, GO:0003676=IEA} 3'-5' exonuclease activity, nucleic acid binding, protein binding Human UniProtKB:Q15038 EXO1 PINC UniProtKB {GO:0005515=PMID:15886194, GO:0035312=PMID:10608837, GO:0008409=PMID:9685493, GO:0045190=GO_REF:0000019, GO:0005634=PMID:14676842, GO:0006310=PMID:10364235, GO:0051908=PMID:11842105, GO:0016446=GO_REF:0000019, GO:0003677=PMID:11842105, GO:0046872=GO_REF:0000037, GO:0004527=PMID:9788596, GO:0004518=GO_REF:0000002, GO:0006281=PMID:10364235, GO:0007126=GO_REF:0000037, GO:0045145=PMID:10608837, GO:0004523=PMID:10364235, GO:0043566=GO_REF:0000019, GO:0048256=PMID:11842105, GO:0006298=PMID:14636568, GO:0002455=GO_REF:0000019} Q9UQ84 Exonuclease 1 protein 20061106 {GO:0005515=IPI, GO:0035312=IDA, GO:0008409=ISS, GO:0045190=IEA, GO:0005634=IDA, GO:0006310=IGI, GO:0051908=IDA, GO:0016446=IEA, GO:0003677=IDA, GO:0046872=IEA, GO:0004527=TAS, GO:0004518=IEA, GO:0006281=TAS, GO:0007126=IEA, GO:0045145=IDA, GO:0004523=TAS, GO:0043566=IEA, GO:0048256=IDA, GO:0006298=IDA, GO:0002455=IEA} DNA recombination, DNA repair, humoral immune response mediated by circulating immunoglobulin, isotype switching, meiosis, mismatch repair, somatic hypermutation of immunoglobulin genes nucleus 5'-3' exodeoxyribonuclease activity, 5'-3' exonuclease activity, DNA binding, double-stranded DNA specific 5'-3' exodeoxyribonuclease activity, exonuclease activity, flap endonuclease activity, metal ion binding, nuclease activity, protein binding, ribonuclease H activity, single-stranded DNA specific 5'-3' exodeoxyribonuclease activity, structure-specific DNA binding Human EXOC1 Reactome UniProtKB {GO:0000145=PMID:11406615, GO:0005886=Reactome:REACT_15394, GO:0006887=PMID:11406615, GO:0015031=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0016044=Reactome:REACT_11123} Q9NV70 Exocyst complex component 1 protein 20130301 {GO:0000145=NAS, GO:0005886=TAS, GO:0006887=NAS, GO:0015031=IEA, GO:0044267=TAS, GO:0016044=TAS} cellular membrane organization, cellular protein metabolic process, exocytosis, protein transport exocyst, plasma membrane Human EXOC2 Reactome UniProtKB {GO:0005515=PMID:19166349, GO:0047485=GO_REF:0000019, GO:0005886=Reactome:REACT_15394, GO:0015031=GO_REF:0000037, GO:0006887=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0017160=GO_REF:0000019, GO:0016044=Reactome:REACT_11123} Q96KP1 Exocyst complex component 2 protein 20130301 {GO:0005515=IPI, GO:0047485=IEA, GO:0005886=TAS, GO:0015031=IEA, GO:0006887=IEA, GO:0044267=TAS, GO:0017160=IEA, GO:0016044=TAS} cellular membrane organization, cellular protein metabolic process, exocytosis, protein transport plasma membrane Ral GTPase binding, protein N-terminus binding, protein binding Human EXOC3 Reactome UniProtKB {GO:0005515=PMID:18329369, GO:0000145=GO_REF:0000002, GO:0015031=GO_REF:0000037, GO:0006887=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0016044=Reactome:REACT_11123, GO:0030667=Reactome:REACT_15394} O60645 Exocyst complex component 3 protein 20130301 {GO:0005515=IPI, GO:0000145=IEA, GO:0015031=IEA, GO:0006887=IEA, GO:0044267=TAS, GO:0016044=TAS, GO:0030667=TAS} cellular membrane organization, cellular protein metabolic process, exocytosis, protein transport exocyst, secretory granule membrane protein binding Human EXOC4 LIFEdb UniProtKB {GO:0005737=GO_REF:0000054, GO:0047485=PMID:18480549, GO:0000145=GO_REF:0000002, GO:0005886=Reactome:REACT_15394, GO:0032584=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0016044=Reactome:REACT_11123, GO:0035748=GO_REF:0000019, GO:0006904=GO_REF:0000002} Q96A65 Exocyst complex component 4 protein 20100607 {GO:0005737=IDA, GO:0047485=IPI, GO:0000145=IEA, GO:0005886=TAS, GO:0032584=IEA, GO:0015031=IEA, GO:0044267=TAS, GO:0016044=TAS, GO:0035748=IEA, GO:0006904=IEA} cellular membrane organization, cellular protein metabolic process, protein transport, vesicle docking involved in exocytosis cytoplasm, exocyst, growth cone membrane, myelin sheath abaxonal region, plasma membrane protein N-terminus binding Human EXOC5 Reactome UniProtKB {GO:0005737=PMID:9119050, GO:0047485=GO_REF:0000019, GO:0006892=PMID:9119050, GO:0015031=GO_REF:0000037, GO:0006887=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0016044=Reactome:REACT_11123, GO:0048278=GO_REF:0000002, GO:0005829=Reactome:REACT_15394} O00471 Exocyst complex component 5 protein 20130301 {GO:0005737=TAS, GO:0047485=IEA, GO:0006892=TAS, GO:0015031=IEA, GO:0006887=IEA, GO:0044267=TAS, GO:0016044=TAS, GO:0048278=IEA, GO:0005829=TAS} cellular membrane organization, cellular protein metabolic process, exocytosis, post-Golgi vesicle-mediated transport, protein transport, vesicle docking cytoplasm, cytosol protein N-terminus binding Human EXOC6 Reactome UniProtKB {GO:0000145=GO_REF:0000002, GO:0005886=Reactome:REACT_15394, GO:0030218=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0016044=Reactome:REACT_11123, GO:0006904=GO_REF:0000002} Q8TAG9 Exocyst complex component 6 protein 20130301 {GO:0000145=IEA, GO:0005886=TAS, GO:0030218=IEA, GO:0015031=IEA, GO:0044267=TAS, GO:0016044=TAS, GO:0006904=IEA} cellular membrane organization, cellular protein metabolic process, erythrocyte differentiation, protein transport, vesicle docking involved in exocytosis exocyst, plasma membrane Human EXOC6B UniProtKB UniProtKB {GO:0000145=GO_REF:0000002, GO:0015031=GO_REF:0000037, GO:0006904=GO_REF:0000002} Q9Y2D4 Exocyst complex component 6B protein 20130413 {GO:0000145=IEA, GO:0015031=IEA, GO:0006904=IEA} protein transport, vesicle docking involved in exocytosis exocyst Human UniProtKB-KW:KW-0653 EXOC7 BHF-UCL UniProtKB {GO:0005515=PMID:16148947, GO:0000145=GO_REF:0000002, GO:0005815=PMID:18000879, GO:0005886=Reactome:REACT_15394, GO:0034451=PMID:18000879, GO:0032584=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0006887=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0016044=Reactome:REACT_11123, GO:0005829=GO_REF:0000039} Q9UPT5 Exocyst complex component 7 protein 20080604 {GO:0005515=IPI, GO:0000145=IEA, GO:0005815=IDA, GO:0005886=TAS, GO:0034451=IDA, GO:0032584=IEA, GO:0015031=IEA, GO:0006887=IEA, GO:0044267=TAS, GO:0016044=TAS, GO:0005829=IEA} cellular membrane organization, cellular protein metabolic process, exocytosis, protein transport centriolar satellite, cytosol, exocyst, growth cone membrane, microtubule organizing center, plasma membrane protein binding Human EXOC8 HPA UniProtKB {GO:0005515=PMID:21241894, GO:0005737=GO_REF:0000052, GO:0000145=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0005886=Reactome:REACT_15394, GO:0005634=GO_REF:0000052, GO:0034613=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0006887=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0016044=Reactome:REACT_11123, GO:0030426=GO_REF:0000039} Q8IYI6 Exocyst complex component 8 protein 20101115 {GO:0005515=IPI, GO:0005737=IDA, GO:0000145=IEA, GO:0005543=IEA, GO:0005886=TAS, GO:0005634=IDA, GO:0034613=IEA, GO:0015031=IEA, GO:0006887=IEA, GO:0044267=TAS, GO:0016044=TAS, GO:0030426=IEA} cellular membrane organization, cellular protein localization, cellular protein metabolic process, exocytosis, protein transport cytoplasm, exocyst, growth cone, nucleus, plasma membrane phospholipid binding, protein binding Human EXOG UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0004519=PMID:10231028, GO:0016787=GO_REF:0000002, GO:0005743=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0003676=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q9Y2C4 Nuclease EXOG, mitochondrial protein 20061026 {GO:0008150=ND, GO:0004519=NAS, GO:0016787=IEA, GO:0005743=IEA, GO:0005575=ND, GO:0003676=IEA, GO:0046872=IEA} biological_process cellular_component, mitochondrial inner membrane endonuclease activity, hydrolase activity, metal ion binding, nucleic acid binding Human EXOSC1 HPA UniProtKB {GO:0005515=PMID:15231747, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=PMID:11812149, GO:0006364=GO_REF:0000037, GO:0005730=PMID:11812149, GO:0004532=PMID:17174896, GO:0043928=Reactome:REACT_20619, GO:0005634=GO_REF:0000052, GO:0000178=PMID:20531389, GO:0005829=Reactome:REACT_25297, GO:0000288=Reactome:REACT_20639} Q9Y3B2 Exosome complex component CSL4 protein 20110516 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=NAS, GO:0006364=IEA, GO:0005730=IDA, GO:0004532=IDA, GO:0043928=TAS, GO:0005634=IDA, GO:0000178=IDA, GO:0005829=TAS, GO:0000288=TAS} RNA metabolic process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, rRNA processing cytosol, exosome (RNase complex), nucleolus, nucleus RNA binding, exoribonuclease activity, protein binding Human EXOSC10 HPA UniProtKB {GO:0005515=PMID:17412707, GO:0006396=GO_REF:0000002, GO:0008408=GO_REF:0000002, GO:0000460=PMID:17412707, GO:0071028=PMID:17545563, GO:0003723=GO_REF:0000037, GO:0000956=PMID:17545563, GO:0005730=GO_REF:0000052, GO:0071035=PMID:16455498, GO:0004532=PMID:17174896, GO:0035327=PMID:20699273, GO:0005634=GO_REF:0000052, GO:0009048=GO_REF:0000019, GO:0071034=PMID:19056938, GO:0003676=GO_REF:0000002, GO:0000178=PMID:20531389, GO:0005737=GO_REF:0000052, GO:0000184=PMID:22890540, GO:0000166=GO_REF:0000002, GO:0071044=PMID:18172165, GO:0000176=GO_REF:0000002, GO:0071048=PMID:20699273} Q01780 Exosome component 10 protein 20111111 {GO:0005515=IPI, GO:0006396=IEA, GO:0008408=IEA, GO:0000460=IMP, GO:0071028=IMP, GO:0003723=IEA, GO:0000956=IMP, GO:0005730=IDA, GO:0071035=IMP, GO:0004532=IDA, GO:0035327=IMP, GO:0005634=IDA, GO:0009048=IEA, GO:0071034=IMP, GO:0003676=IEA, GO:0000178=IDA, GO:0005737=IDA, GO:0000184=IMP, GO:0000166=IEA, GO:0071044=IMP, GO:0000176=IEA, GO:0071048=IMP} CUT catabolic process, RNA processing, dosage compensation by inactivation of X chromosome, histone mRNA catabolic process, maturation of 5.8S rRNA, nuclear mRNA surveillance, nuclear polyadenylation-dependent rRNA catabolic process, nuclear retention of unspliced pre-mRNA at the site of transcription, nuclear-transcribed mRNA catabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay cytoplasm, exosome (RNase complex), nuclear exosome (RNase complex), nucleolus, nucleus, transcriptionally active chromatin 3'-5' exonuclease activity, RNA binding, exoribonuclease activity, nucleic acid binding, nucleotide binding, protein binding Human EXOSC2 IntAct UniProtKB {GO:0005515=PMID:20531389, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0030307=PMID:17545563, GO:0003723=GO_REF:0000002, GO:0006364=GO_REF:0000037, GO:0008312=PMID:8600032, GO:0005730=GO_REF:0000039, GO:0043928=Reactome:REACT_20619, GO:0004532=PMID:17174896, GO:0005634=PMID:17545563, GO:0000178=PMID:20531389, GO:0005829=Reactome:REACT_25297, GO:0004527=GO_REF:0000038, GO:0005737=PMID:17545563, GO:0000175=PMID:8600032, GO:0000288=Reactome:REACT_20639} Q13868 Exosome complex component RRP4 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0030307=IMP, GO:0003723=IEA, GO:0006364=IEA, GO:0008312=TAS, GO:0005730=IEA, GO:0043928=TAS, GO:0004532=IDA, GO:0005634=IDA, GO:0000178=IDA, GO:0005829=TAS, GO:0004527=IEA, GO:0005737=IDA, GO:0000175=TAS, GO:0000288=TAS} RNA metabolic process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, positive regulation of cell growth, rRNA processing cytoplasm, cytosol, exosome (RNase complex), nucleolus, nucleus 3'-5'-exoribonuclease activity, 7S RNA binding, RNA binding, exonuclease activity, exoribonuclease activity, protein binding Human UniProtKB:Q8TF46-1 EXOSC3 IntAct UniProtKB {GO:0005515=PMID:21255825, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=GO_REF:0000037, GO:0006364=PMID:11110791, GO:0045190=GO_REF:0000024, GO:0005730=PMID:20531389, GO:0043928=Reactome:REACT_20619, GO:0035327=PMID:20699273, GO:0004532=PMID:17174896, GO:0005634=PMID:17545563, GO:0071034=PMID:19056938, GO:0000178=PMID:20531389, GO:0005829=Reactome:REACT_25297, GO:0045006=PMID:21255825, GO:0005737=PMID:17545563, GO:0000175=PMID:11110791, GO:0000177=PMID:11110791, GO:0000176=PMID:11110791, GO:0000288=Reactome:REACT_20639} Q9NQT5 Exosome complex component RRP40 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=IEA, GO:0006364=IDA, GO:0045190=ISS, GO:0005730=IDA, GO:0043928=TAS, GO:0035327=IMP, GO:0004532=IDA, GO:0005634=IDA, GO:0071034=IMP, GO:0000178=IDA, GO:0005829=TAS, GO:0045006=IDA, GO:0005737=IDA, GO:0000175=NAS, GO:0000177=IDA, GO:0000176=IDA, GO:0000288=TAS} CUT catabolic process, DNA deamination, RNA metabolic process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, isotype switching, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, rRNA processing cytoplasm, cytoplasmic exosome (RNase complex), cytosol, exosome (RNase complex), nuclear exosome (RNase complex), nucleolus, nucleus, transcriptionally active chromatin 3'-5'-exoribonuclease activity, RNA binding, exoribonuclease activity, protein binding Human UniProtKB:Q9Y2L1 EXOSC4 IntAct UniProtKB {GO:0005515=PMID:21255825, GO:0010467=Reactome:REACT_71, GO:0000460=PMID:20368444, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0030307=PMID:17545563, GO:0006364=PMID:11110791, GO:0071028=PMID:17545563, GO:0005730=PMID:11110791, GO:0000956=PMID:17545563, GO:0043928=Reactome:REACT_20619, GO:0035327=PMID:20699273, GO:0004532=PMID:17174896, GO:0005634=PMID:17545563, GO:0000178=PMID:20531389, GO:0005829=Reactome:REACT_25297, GO:0045006=PMID:21255825, GO:0051607=PMID:21791617, GO:0005737=PMID:17545563, GO:0000175=PMID:11110791, GO:0071044=PMID:18172165, GO:0017091=PMID:16912217, GO:0000288=Reactome:REACT_20639} Q9NPD3 Exosome complex component RRP41 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0000460=IMP, GO:0016070=TAS, GO:0016071=TAS, GO:0030307=IMP, GO:0006364=NAS, GO:0071028=IMP, GO:0005730=NAS, GO:0000956=IMP, GO:0043928=TAS, GO:0035327=IMP, GO:0004532=IDA, GO:0005634=IDA, GO:0000178=IDA, GO:0005829=TAS, GO:0045006=IDA, GO:0051607=IMP, GO:0005737=IDA, GO:0000175=NAS, GO:0071044=IMP, GO:0017091=IDA, GO:0000288=TAS} DNA deamination, RNA metabolic process, defense response to virus, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, histone mRNA catabolic process, mRNA metabolic process, maturation of 5.8S rRNA, nuclear mRNA surveillance, nuclear-transcribed mRNA catabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, positive regulation of cell growth, rRNA processing cytoplasm, cytosol, exosome (RNase complex), nucleolus, nucleus, transcriptionally active chromatin 3'-5'-exoribonuclease activity, AU-rich element binding, exoribonuclease activity, protein binding Human UniProtKB:Q9NQT5 EXOSC5 Reactome UniProtKB {GO:0005515=PMID:11812149, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=GO_REF:0000037, GO:0006364=PMID:11110791, GO:0005730=PMID:11110791, GO:0043928=Reactome:REACT_20619, GO:0035327=PMID:20699273, GO:0004532=PMID:17174896, GO:0000178=PMID:20531389, GO:0005829=Reactome:REACT_25297, GO:0045006=PMID:21255825, GO:0005737=PMID:11110791, GO:0051607=PMID:21791617, GO:0000175=PMID:11110791, GO:0000288=Reactome:REACT_20639} Q9NQT4 Exosome complex component RRP46 protein 20130301 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=IEA, GO:0006364=NAS, GO:0005730=NAS, GO:0043928=TAS, GO:0035327=IMP, GO:0004532=IDA, GO:0000178=IDA, GO:0005829=TAS, GO:0045006=IDA, GO:0005737=NAS, GO:0051607=IMP, GO:0000175=NAS, GO:0000288=TAS} DNA deamination, RNA metabolic process, defense response to virus, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, rRNA processing cytoplasm, cytosol, exosome (RNase complex), nucleolus, transcriptionally active chromatin 3'-5'-exoribonuclease activity, RNA binding, exoribonuclease activity, protein binding Human EXOSC6 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=GO_REF:0000037, GO:0006364=GO_REF:0000037, GO:0045190=GO_REF:0000024, GO:0005730=GO_REF:0000039, GO:0004532=PMID:17174896, GO:0043928=Reactome:REACT_20619, GO:0000178=PMID:20531389, GO:0005829=Reactome:REACT_25297, GO:0045006=PMID:21255825, GO:0000288=Reactome:REACT_20639} Q5RKV6 Exosome complex component MTR3 protein 20130301 {GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=IEA, GO:0006364=IEA, GO:0045190=ISS, GO:0005730=IEA, GO:0004532=IDA, GO:0043928=TAS, GO:0000178=IDA, GO:0005829=TAS, GO:0045006=IDA, GO:0000288=TAS} DNA deamination, RNA metabolic process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, isotype switching, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, rRNA processing cytosol, exosome (RNase complex), nucleolus RNA binding, exoribonuclease activity Human EXOSC7 Reactome UniProtKB {GO:0005515=PMID:21876179, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006364=PMID:11849973, GO:0003723=PMID:11849973, GO:0005730=GO_REF:0000039, GO:0043928=Reactome:REACT_20619, GO:0004532=PMID:17174896, GO:0000178=PMID:20531389, GO:0006401=PMID:11719186, GO:0005829=Reactome:REACT_25297, GO:0000175=PMID:11849973, GO:0000288=Reactome:REACT_20639} Q15024 Exosome complex component RRP42 protein 20130301 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0006364=TAS, GO:0003723=TAS, GO:0005730=IEA, GO:0043928=TAS, GO:0004532=IDA, GO:0000178=IDA, GO:0006401=NAS, GO:0005829=TAS, GO:0000175=TAS, GO:0000288=TAS} RNA catabolic process, RNA metabolic process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, rRNA processing cytosol, exosome (RNase complex), nucleolus 3'-5'-exoribonuclease activity, RNA binding, exoribonuclease activity, protein binding Human EXOSC8 IntAct UniProtKB {GO:0005515=PMID:21255825, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006364=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0043928=Reactome:REACT_20619, GO:0004532=PMID:17174896, GO:0005634=PMID:17545563, GO:0000178=PMID:20531389, GO:0005829=Reactome:REACT_25297, GO:0008150=GO_REF:0000015, GO:0005737=PMID:17545563, GO:0017091=PMID:16912217, GO:0000288=Reactome:REACT_20639} Q96B26 Exosome complex component RRP43 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0006364=IEA, GO:0005730=IEA, GO:0043928=TAS, GO:0004532=IDA, GO:0005634=IDA, GO:0000178=IDA, GO:0005829=TAS, GO:0008150=ND, GO:0005737=IDA, GO:0017091=IDA, GO:0000288=TAS} RNA metabolic process, biological_process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, rRNA processing cytoplasm, cytosol, exosome (RNase complex), nucleolus, nucleus AU-rich element binding, exoribonuclease activity, protein binding Human UniProtKB:Q9NQT5 EXOSC9 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0030307=PMID:17545563, GO:0003723=PMID:11879549, GO:0006364=PMID:11879549, GO:0071028=PMID:17545563, GO:0005730=GO_REF:0000039, GO:0071035=PMID:16455498, GO:0000956=PMID:17545563, GO:0043928=Reactome:REACT_20619, GO:0004532=PMID:17174896, GO:0005634=PMID:17545563, GO:0000178=PMID:20531389, GO:0005829=Reactome:REACT_25297, GO:0005737=PMID:17545563, GO:0006955=PMID:11879549, GO:0000175=PMID:11879549, GO:0000176=PMID:22791713, GO:0017091=PMID:11782436, GO:0000288=Reactome:REACT_20639} Q06265 Exosome complex component RRP45 protein 20130301 {GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0030307=IMP, GO:0003723=NAS, GO:0006364=NAS, GO:0071028=IMP, GO:0005730=IEA, GO:0071035=IMP, GO:0000956=IMP, GO:0043928=TAS, GO:0004532=IDA, GO:0005634=IDA, GO:0000178=IDA, GO:0005829=TAS, GO:0005737=IDA, GO:0006955=NAS, GO:0000175=NAS, GO:0000176=IDA, GO:0017091=IDA, GO:0000288=TAS} RNA metabolic process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, immune response, mRNA metabolic process, nuclear mRNA surveillance, nuclear polyadenylation-dependent rRNA catabolic process, nuclear-transcribed mRNA catabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, positive regulation of cell growth, rRNA processing cytoplasm, cytosol, exosome (RNase complex), nuclear exosome (RNase complex), nucleolus, nucleus 3'-5'-exoribonuclease activity, AU-rich element binding, RNA binding, exoribonuclease activity Human EXPH5 UniProtKB UniProtKB {GO:0045921=PMID:19966785, GO:0017137=PMID:16880209, GO:0071985=PMID:19966785, GO:0050714=PMID:19966785, GO:0006886=GO_REF:0000002, GO:0005768=PMID:19966785} Q8NEV8 Exophilin-5 protein 20110803 {GO:0045921=IMP, GO:0017137=IPI, GO:0071985=IMP, GO:0050714=IMP, GO:0006886=IEA, GO:0005768=IDA} intracellular protein transport, multivesicular body sorting pathway, positive regulation of exocytosis, positive regulation of protein secretion endosome Rab GTPase binding Human UniProtKB:O00194 EXT1 BHF-UCL UniProtKB {GO:0007369=GO_REF:0000019, GO:0005783=PMID:9620772, GO:0030176=GO_REF:0000024, GO:0015012=PMID:10639137, GO:0044281=Reactome:REACT_111217, GO:0015014=PMID:17761672, GO:0042803=PMID:12907669, GO:0021772=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0033692=PMID:12907669, GO:0030203=Reactome:REACT_121315, GO:0008375=PMID:12907669, GO:0050508=PMID:12907669, GO:0005794=PMID:10639137, GO:0050509=PMID:12907669, GO:0072498=GO_REF:0000019, GO:0046982=PMID:12907669, GO:0005975=Reactome:REACT_474, GO:0016757=PMID:12907669, GO:0015020=PMID:12907669, GO:0006024=PMID:12907669, GO:0007165=PMID:10878610, GO:0001501=PMID:9620772, GO:0007492=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0000139=PMID:12907669, GO:0001503=PMID:7550340, GO:0005789=PMID:9620772, GO:0006486=GO_REF:0000041, GO:0007498=GO_REF:0000019, GO:0016021=PMID:9620772, GO:0042328=PMID:12907669} Q16394 Exostosin-1 protein 20080228 {GO:0007369=IEA, GO:0005783=IDA, GO:0030176=ISS, GO:0015012=IDA, GO:0044281=TAS, GO:0015014=IMP, GO:0042803=IDA, GO:0021772=IEA, GO:0007411=IEA, GO:0033692=IDA, GO:0030203=TAS, GO:0008375=IDA, GO:0050508=NAS, GO:0005794=IDA, GO:0050509=NAS, GO:0072498=IEA, GO:0046982=IPI, GO:0005975=TAS, GO:0016757=IDA, GO:0015020=IDA, GO:0006024=IDA, GO:0007165=TAS, GO:0001501=TAS, GO:0007492=IEA, GO:0016020=IEA, GO:0000139=TAS, GO:0001503=IMP, GO:0005789=NAS, GO:0006486=IEA, GO:0007498=IEA, GO:0016021=TAS, GO:0042328=NAS} axon guidance, carbohydrate metabolic process, cellular polysaccharide biosynthetic process, embryonic skeletal joint development, endoderm development, gastrulation, glycosaminoglycan biosynthetic process, glycosaminoglycan metabolic process, heparan sulfate proteoglycan biosynthetic process, heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process, mesoderm development, olfactory bulb development, ossification, protein glycosylation, signal transduction, skeletal system development, small molecule metabolic process Golgi apparatus, Golgi membrane, endoplasmic reticulum, endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane, integral to membrane, membrane N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity, acetylglucosaminyltransferase activity, glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity, glucuronosyltransferase activity, heparan sulfate N-acetylglucosaminyltransferase activity, protein heterodimerization activity, protein homodimerization activity, transferase activity, transferring glycosyl groups Human EXT2 BHF-UCL UniProtKB {GO:0005783=GO_REF:0000024, GO:0031227=GO_REF:0000002, GO:0015012=PMID:17761672, GO:0044281=Reactome:REACT_111217, GO:0015014=PMID:17761672, GO:0042803=PMID:12907669, GO:0030154=GO_REF:0000019, GO:0033692=PMID:12907669, GO:0030203=Reactome:REACT_121315, GO:0008375=PMID:12907669, GO:0050508=GO_REF:0000003, GO:0050509=PMID:12907669, GO:0005794=GO_REF:0000024, GO:0001707=GO_REF:0000019, GO:0046982=PMID:12907669, GO:0005975=Reactome:REACT_474, GO:0016757=PMID:12907669, GO:0015020=PMID:12907669, GO:0006024=PMID:12907669, GO:0007165=PMID:10878610, GO:0000139=Reactome:REACT_121320, GO:0001503=PMID:9326317, GO:0005789=PMID:10639137, GO:0006486=GO_REF:0000041, GO:0016021=GO_REF:0000037, GO:0042328=PMID:12907669} Q93063 Exostosin-2 protein 20080228 {GO:0005783=ISS, GO:0031227=IEA, GO:0015012=IMP, GO:0044281=TAS, GO:0015014=IMP, GO:0042803=IDA, GO:0030154=IEA, GO:0033692=IDA, GO:0030203=TAS, GO:0008375=IDA, GO:0050508=IEA, GO:0050509=NAS, GO:0005794=ISS, GO:0001707=IEA, GO:0046982=IPI, GO:0005975=TAS, GO:0016757=IDA, GO:0015020=IDA, GO:0006024=IDA, GO:0007165=TAS, GO:0000139=TAS, GO:0001503=IMP, GO:0005789=TAS, GO:0006486=IEA, GO:0016021=IEA, GO:0042328=NAS} carbohydrate metabolic process, cell differentiation, cellular polysaccharide biosynthetic process, glycosaminoglycan biosynthetic process, glycosaminoglycan metabolic process, heparan sulfate proteoglycan biosynthetic process, heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process, mesoderm formation, ossification, protein glycosylation, signal transduction, small molecule metabolic process Golgi apparatus, Golgi membrane, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, intrinsic to endoplasmic reticulum membrane N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity, acetylglucosaminyltransferase activity, glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity, glucuronosyltransferase activity, heparan sulfate N-acetylglucosaminyltransferase activity, protein heterodimerization activity, protein homodimerization activity, transferase activity, transferring glycosyl groups Human EXTL1 PINC UniProtKB {GO:0001501=PMID:9037597, GO:0050508=GO_REF:0000003, GO:0031227=GO_REF:0000002, GO:0006486=GO_REF:0000041, GO:0016021=GO_REF:0000037} Q92935 Exostosin-like 1 protein 20030904 {GO:0001501=TAS, GO:0050508=IEA, GO:0031227=IEA, GO:0006486=IEA, GO:0016021=IEA} protein glycosylation, skeletal system development integral to membrane, intrinsic to endoplasmic reticulum membrane glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity Human EXTL3 BHF-UCL UniProtKB {GO:0016758=GO_REF:0000002, GO:0030307=GO_REF:0000019, GO:0005783=PMID:10639137, GO:0031227=GO_REF:0000002, GO:0015012=GO_REF:0000041, GO:0046872=GO_REF:0000037, GO:0030968=Reactome:REACT_18356, GO:0001888=GO_REF:0000003, GO:0016020=GO_REF:0000002, GO:0005789=Reactome:REACT_115825, GO:0016021=GO_REF:0000037, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015} O43909 Exostosin-like 3 protein 20080228 {GO:0016758=IEA, GO:0030307=IEA, GO:0005783=IDA, GO:0031227=IEA, GO:0015012=IEA, GO:0046872=IEA, GO:0030968=TAS, GO:0001888=IEA, GO:0016020=IEA, GO:0005789=TAS, GO:0016021=IEA, GO:0006987=TAS, GO:0044267=TAS} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, heparan sulfate proteoglycan biosynthetic process, positive regulation of cell growth endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, intrinsic to endoplasmic reticulum membrane, membrane glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity, metal ion binding, transferase activity, transferring hexosyl groups Human EYA1 PINC UniProtKB {GO:0005515=PMID:15141091, GO:0001656=GO_REF:0000019, GO:0007389=GO_REF:0000019, GO:0001658=GO_REF:0000019, GO:0007605=PMID:9020840, GO:0000132=GO_REF:0000019, GO:0035088=GO_REF:0000019, GO:0005634=PMID:19497856, GO:0048704=GO_REF:0000019, GO:0045739=PMID:19234442, GO:0048752=GO_REF:0000019, GO:0009653=PMID:9020840, GO:0046872=GO_REF:0000037, GO:0006302=PMID:19234442, GO:0005737=PMID:19497856, GO:0010212=PMID:19234442, GO:0045944=GO_REF:0000019, GO:0090103=GO_REF:0000019, GO:0072513=GO_REF:0000019, GO:0014706=GO_REF:0000019, GO:0042474=GO_REF:0000019, GO:0042473=GO_REF:0000019, GO:0004725=PMID:19234442, GO:0045747=GO_REF:0000019, GO:0050679=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0016576=PMID:19234442, GO:0016925=GO_REF:0000024, GO:0035909=GO_REF:0000019, GO:0007275=GO_REF:0000002, GO:0003151=GO_REF:0000019, GO:0071600=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0060037=GO_REF:0000019, GO:0045165=GO_REF:0000019, GO:0045664=GO_REF:0000019, GO:0060487=GO_REF:0000019, GO:0034613=GO_REF:0000019} Q99502 Eyes absent homolog 1 protein 20030904 {GO:0005515=IPI, GO:0001656=IEA, GO:0007389=IEA, GO:0001658=IEA, GO:0007605=TAS, GO:0000132=IEA, GO:0035088=IEA, GO:0005634=IDA, GO:0048704=IEA, GO:0045739=IMP, GO:0048752=IEA, GO:0009653=TAS, GO:0046872=IEA, GO:0006302=IMP, GO:0005737=IDA, GO:0010212=IDA, GO:0045944=IEA, GO:0090103=IEA, GO:0072513=IEA, GO:0014706=IEA, GO:0042474=IEA, GO:0042473=IEA, GO:0004725=IDA, GO:0045747=IEA, GO:0050679=IEA, GO:0043066=IEA, GO:0016576=IDA, GO:0016925=ISS, GO:0035909=IEA, GO:0007275=IEA, GO:0003151=IEA, GO:0071600=IEA, GO:0006351=IEA, GO:0060037=IEA, GO:0045165=IEA, GO:0045664=IEA, GO:0060487=IEA, GO:0034613=IEA} anatomical structure morphogenesis, aorta morphogenesis, branching involved in ureteric bud morphogenesis, cell fate commitment, cellular protein localization, cochlea morphogenesis, double-strand break repair, embryonic skeletal system morphogenesis, establishment of mitotic spindle orientation, establishment or maintenance of apical/basal cell polarity, histone dephosphorylation, lung epithelial cell differentiation, metanephros development, middle ear morphogenesis, multicellular organismal development, negative regulation of apoptotic process, otic vesicle morphogenesis, outer ear morphogenesis, outflow tract morphogenesis, pattern specification process, pharyngeal system development, positive regulation of DNA repair, positive regulation of Notch signaling pathway, positive regulation of epithelial cell proliferation, positive regulation of secondary heart field cardioblast proliferation, positive regulation of transcription from RNA polymerase II promoter, protein sumoylation, regulation of neuron differentiation, response to ionizing radiation, semicircular canal morphogenesis, sensory perception of sound, striated muscle tissue development, transcription, DNA-dependent cytoplasm, nucleus metal ion binding, protein binding, protein tyrosine phosphatase activity Human EYA2 GOC UniProtKB {GO:0005515=PMID:19497856, GO:0006355=GO_REF:0000037, GO:0000287=PMID:19351884, GO:0016576=PMID:19351884, GO:0006915=GO_REF:0000019, GO:0007275=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0035335=PMID:19351884, GO:0006351=GO_REF:0000037, GO:0005739=GO_REF:0000052, GO:0007501=PMID:9020840, GO:0006281=GO_REF:0000037, GO:0014706=GO_REF:0000019, GO:0004725=PMID:19351884} O00167 Eyes absent homolog 2 protein 20130413 {GO:0005515=IPI, GO:0006355=IEA, GO:0000287=IDA, GO:0016576=IDA, GO:0006915=IEA, GO:0007275=IEA, GO:0005634=IEA, GO:0035335=IDA, GO:0006351=IEA, GO:0005739=IDA, GO:0007501=TAS, GO:0006281=IEA, GO:0014706=IEA, GO:0004725=IDA} DNA repair, apoptotic process, histone dephosphorylation, mesodermal cell fate specification, multicellular organismal development, peptidyl-tyrosine dephosphorylation, regulation of transcription, DNA-dependent, striated muscle tissue development, transcription, DNA-dependent mitochondrion, nucleus magnesium ion binding, protein binding, protein tyrosine phosphatase activity Human EYA3 GOC UniProtKB {GO:0005515=PMID:19234442, GO:0005667=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0016576=PMID:19234442, GO:0005634=PMID:19234442, GO:0007275=GO_REF:0000037, GO:0045739=PMID:19234442, GO:0009653=PMID:9020840, GO:0035335=PMID:19351884, GO:0006351=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0006302=PMID:19234442, GO:0005737=GO_REF:0000039, GO:0003682=GO_REF:0000019, GO:0010212=PMID:19234442, GO:0008138=GO_REF:0000019, GO:0007601=PMID:9049631, GO:0004725=PMID:19234442} Q99504 Eyes absent homolog 3 protein 20130413 {GO:0005515=IPI, GO:0005667=IEA, GO:0006355=IEA, GO:0016576=IDA, GO:0005634=IDA, GO:0007275=IEA, GO:0045739=IMP, GO:0009653=TAS, GO:0035335=IDA, GO:0006351=IEA, GO:0046872=IEA, GO:0006302=IMP, GO:0005737=IEA, GO:0003682=IEA, GO:0010212=IDA, GO:0008138=IEA, GO:0007601=TAS, GO:0004725=IDA} anatomical structure morphogenesis, double-strand break repair, histone dephosphorylation, multicellular organismal development, peptidyl-tyrosine dephosphorylation, positive regulation of DNA repair, regulation of transcription, DNA-dependent, response to ionizing radiation, transcription, DNA-dependent, visual perception cytoplasm, nucleus, transcription factor complex chromatin binding, metal ion binding, protein binding, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human EYA4 PINC UniProtKB {GO:0006355=GO_REF:0000037, GO:0007605=GO_REF:0000019, GO:0007275=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0009653=PMID:9887327, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0006281=GO_REF:0000037, GO:0042474=GO_REF:0000019, GO:0007601=PMID:9887327, GO:0004725=GO_REF:0000003, GO:0016568=GO_REF:0000037} O95677 Eyes absent homolog 4 protein 20030904 {GO:0006355=IEA, GO:0007605=IEA, GO:0007275=IEA, GO:0005634=IEA, GO:0009653=TAS, GO:0046872=IEA, GO:0006351=IEA, GO:0005737=IEA, GO:0006281=IEA, GO:0042474=IEA, GO:0007601=TAS, GO:0004725=IEA, GO:0016568=IEA} DNA repair, anatomical structure morphogenesis, chromatin modification, middle ear morphogenesis, multicellular organismal development, regulation of transcription, DNA-dependent, sensory perception of sound, transcription, DNA-dependent, visual perception cytoplasm, nucleus metal ion binding, protein tyrosine phosphatase activity Human EZH1 HPA UniProtKB {GO:0035098=PMID:20075857, GO:0003682=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000122=GO_REF:0000019, GO:0009653=PMID:8921387, GO:0046976=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0018024=GO_REF:0000002} Q92800 Histone-lysine N-methyltransferase EZH1 protein 20090616 {GO:0035098=IDA, GO:0003682=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0000122=IEA, GO:0009653=TAS, GO:0046976=IEA, GO:0006351=IEA, GO:0018024=IEA} anatomical structure morphogenesis, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent ESC/E(Z) complex, nucleolus, nucleus chromatin binding, histone methyltransferase activity (H3-K27 specific), histone-lysine N-methyltransferase activity NOT Human EZH2 IntAct UniProtKB {GO:0005515=PMID:22897849, GO:0071902=PMID:20154697, GO:0021695=GO_REF:0000019, GO:0006325=PMID:8921387, GO:0010718=PMID:20154697, GO:0042054=PMID:15385962, GO:0000084=GO_REF:0000019, GO:0043406=PMID:20154697, GO:0042127=GO_REF:0000019, GO:0014013=GO_REF:0000019, GO:0051154=GO_REF:0000019, GO:0034244=GO_REF:0000019, GO:0070734=GO_REF:0000019, GO:0006355=PMID:8921387, GO:0001047=GO_REF:0000019, GO:0000122=PMID:20154697, GO:0003677=PMID:8954776, GO:0006351=GO_REF:0000037, GO:0070314=GO_REF:0000019, GO:0018024=GO_REF:0000003, GO:0043565=GO_REF:0000019, GO:0045605=GO_REF:0000019, GO:0035098=PMID:15385962, GO:0032320=PMID:20154697, GO:0048387=PMID:16179254, GO:0003682=PMID:20154697, GO:0045814=PMID:20154697, GO:0045120=GO_REF:0000019, GO:0045892=PMID:16179254} Q15910 Histone-lysine N-methyltransferase EZH2 protein 20130415 {GO:0005515=IPI, GO:0071902=IDA, GO:0021695=IEA, GO:0006325=TAS, GO:0010718=IDA, GO:0042054=IDA, GO:0000084=IEA, GO:0043406=IDA, GO:0042127=IEA, GO:0014013=IEA, GO:0051154=IEA, GO:0034244=IEA, GO:0070734=IEA, GO:0006355=TAS, GO:0001047=IEA, GO:0000122=IDA, GO:0003677=TAS, GO:0006351=IEA, GO:0070314=IEA, GO:0018024=IEA, GO:0043565=IEA, GO:0045605=IEA, GO:0035098=IDA, GO:0032320=IDA, GO:0048387=IMP, GO:0003682=IDA, GO:0045814=IDA, GO:0045120=IEA, GO:0045892=IMP} G1 to G0 transition, S phase of mitotic cell cycle, cerebellar cortex development, chromatin organization, histone H3-K27 methylation, negative regulation of epidermal cell differentiation, negative regulation of gene expression, epigenetic, negative regulation of retinoic acid receptor signaling pathway, negative regulation of striated muscle cell differentiation, negative regulation of transcription elongation from RNA polymerase II promoter, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of MAP kinase activity, positive regulation of Ras GTPase activity, positive regulation of epithelial to mesenchymal transition, positive regulation of protein serine/threonine kinase activity, regulation of cell proliferation, regulation of gliogenesis, regulation of transcription, DNA-dependent, transcription, DNA-dependent ESC/E(Z) complex, pronucleus DNA binding, chromatin binding, core promoter binding, histone methyltransferase activity, histone-lysine N-methyltransferase activity, protein binding, sequence-specific DNA binding Human UniProtKB:Q8IXJ9 EZR HPA UniProtKB {GO:0008092=GO_REF:0000002, GO:0005515=PMID:21282464, GO:0005886=GO_REF:0000052, GO:0008360=GO_REF:0000037, GO:0005884=PMID:11598191, GO:0031528=GO_REF:0000039, GO:0035088=GO_REF:0000019, GO:0030175=PMID:12082081, GO:0015629=PMID:10793131, GO:0005829=Reactome:REACT_22317, GO:0016323=GO_REF:0000024, GO:0016324=GO_REF:0000039, GO:0005737=GO_REF:0000002, GO:0051015=PMID:10793131, GO:0007411=Reactome:REACT_18266, GO:0030855=GO_REF:0000019, GO:0007159=PMID:12082081, GO:0022614=PMID:12082081, GO:0005932=GO_REF:0000019, GO:0005856=GO_REF:0000002, GO:0050839=PMID:12082081, GO:0007016=PMID:10793131, GO:0051017=PMID:10793131, GO:0005730=GO_REF:0000052, GO:0045177=PMID:12082081, GO:0032587=GO_REF:0000039, GO:0001726=PMID:9852149, GO:0005902=PMID:12082081, GO:0030863=PMID:11598191, GO:0001931=GO_REF:0000019, GO:0005925=PMID:21282464, GO:0019898=PMID:7844168} P15311 Ezrin protein 20100326 {GO:0008092=IEA, GO:0005515=IPI, GO:0005886=IDA, GO:0008360=IEA, GO:0005884=IDA, GO:0031528=IEA, GO:0035088=IEA, GO:0030175=IDA, GO:0015629=IDA, GO:0005829=TAS, GO:0016323=ISS, GO:0016324=IEA, GO:0005737=IEA, GO:0051015=IDA, GO:0007411=TAS, GO:0030855=IEA, GO:0007159=IEP, GO:0022614=IEP, GO:0005932=IEA, GO:0005856=IEA, GO:0050839=IPI, GO:0007016=NAS, GO:0051017=IDA, GO:0005730=IDA, GO:0045177=IDA, GO:0032587=IEA, GO:0001726=IDA, GO:0005902=IDA, GO:0030863=TAS, GO:0001931=IEA, GO:0005925=IDA, GO:0019898=IDA} actin filament bundle assembly, axon guidance, cytoskeletal anchoring at plasma membrane, epithelial cell differentiation, establishment or maintenance of apical/basal cell polarity, leukocyte cell-cell adhesion, membrane to membrane docking, regulation of cell shape actin cytoskeleton, actin filament, apical part of cell, apical plasma membrane, basolateral plasma membrane, cortical cytoskeleton, cytoplasm, cytoskeleton, cytosol, extrinsic to membrane, filopodium, focal adhesion, microtubule basal body, microvillus, microvillus membrane, nucleolus, plasma membrane, ruffle, ruffle membrane, uropod actin filament binding, cell adhesion molecule binding, cytoskeletal protein binding, protein binding Human F10 UniProtKB UniProtKB {GO:0005515=PMID:6323392, GO:0051897=PMID:18612547, GO:0030335=PMID:18612547, GO:0004252=GO_REF:0000002, GO:0005886=Reactome:REACT_1446, GO:0005796=Reactome:REACT_1644, GO:0005509=GO_REF:0000002, GO:0005576=GO_REF:0000002, GO:0031233=PMID:17469850, GO:0017187=Reactome:REACT_1132, GO:0005543=PMID:17469850, GO:0007596=PMID:17469850, GO:0007597=Reactome:REACT_326, GO:0007598=Reactome:REACT_1573, GO:0006508=GO_REF:0000038, GO:0005788=Reactome:REACT_1565, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q5JVE8 Factor X light chain protein 20130413 {GO:0005515=IPI, GO:0051897=IDA, GO:0030335=TAS, GO:0004252=IEA, GO:0005886=TAS, GO:0005796=TAS, GO:0005509=IEA, GO:0005576=IEA, GO:0031233=IC, GO:0017187=TAS, GO:0005543=IDA, GO:0007596=IC, GO:0007597=TAS, GO:0007598=TAS, GO:0006508=IEA, GO:0005788=TAS, GO:0044267=TAS, GO:0043687=TAS} blood coagulation, blood coagulation, extrinsic pathway, blood coagulation, intrinsic pathway, cellular protein metabolic process, peptidyl-glutamic acid carboxylation, positive regulation of cell migration, positive regulation of protein kinase B signaling cascade, post-translational protein modification, proteolysis Golgi lumen, endoplasmic reticulum lumen, extracellular region, intrinsic to external side of plasma membrane, plasma membrane calcium ion binding, phospholipid binding, protein binding, serine-type endopeptidase activity Human UniProtKB-KW:KW-0645 F11 BHF-UCL UniProtKB {GO:0005515=PMID:15545266, GO:0004252=PMID:9593722, GO:0005886=Reactome:REACT_2073, GO:0051919=PMID:89876, GO:0005576=Reactome:REACT_177, GO:0005615=PMID:89876, GO:0030193=GO_REF:0000019, GO:0016020=PMID:9593722, GO:0007596=Reactome:REACT_2051, GO:0007597=Reactome:REACT_326, GO:0006508=GO_REF:0000037, GO:0031639=PMID:89876, GO:0070009=GO_REF:0000019, GO:0008201=GO_REF:0000037, GO:0044421=GO_REF:0000019} P03951 Coagulation factor XI protein 20081015 {GO:0005515=IPI, GO:0004252=NAS, GO:0005886=TAS, GO:0051919=IDA, GO:0005576=TAS, GO:0005615=IDA, GO:0030193=IEA, GO:0016020=NAS, GO:0007596=TAS, GO:0007597=TAS, GO:0006508=IEA, GO:0031639=IDA, GO:0070009=IEA, GO:0008201=IEA, GO:0044421=IEA} blood coagulation, blood coagulation, intrinsic pathway, plasminogen activation, positive regulation of fibrinolysis, proteolysis, regulation of blood coagulation extracellular region, extracellular region part, extracellular space, membrane, plasma membrane heparin binding, protein binding, serine-type aminopeptidase activity, serine-type endopeptidase activity Human F11R Reactome UniProtKB {GO:0030054=Reactome:REACT_121319, GO:0005886=Reactome:REACT_19353, GO:0034329=Reactome:REACT_20676, GO:0050900=Reactome:REACT_12051, GO:0045216=Reactome:REACT_19331, GO:0006954=PMID:10395639, GO:0070830=Reactome:REACT_19373, GO:0005911=PMID:10395639, GO:0007596=Reactome:REACT_604, GO:0019048=GO_REF:0000037, GO:0030855=GO_REF:0000019, GO:0007179=Reactome:REACT_120726, GO:0016021=GO_REF:0000037, GO:0005923=GO_REF:0000039, GO:0007155=GO_REF:0000019} Q9Y624 Junctional adhesion molecule A protein 20090827 {GO:0030054=TAS, GO:0005886=TAS, GO:0034329=TAS, GO:0050900=TAS, GO:0045216=TAS, GO:0006954=TAS, GO:0070830=TAS, GO:0005911=TAS, GO:0007596=TAS, GO:0019048=IEA, GO:0030855=IEA, GO:0007179=TAS, GO:0016021=IEA, GO:0005923=IEA, GO:0007155=IEA} blood coagulation, cell adhesion, cell junction assembly, cell-cell junction organization, epithelial cell differentiation, inflammatory response, leukocyte migration, tight junction assembly, transforming growth factor beta receptor signaling pathway, virus-host interaction cell junction, cell-cell junction, integral to membrane, plasma membrane, tight junction Human F12 BHF-UCL UniProtKB {GO:0005515=PMID:8710908, GO:0016540=PMID:18725990, GO:0005886=Reactome:REACT_1455, GO:0004252=PMID:18725990, GO:0051919=PMID:89876, GO:0005576=Reactome:REACT_1455, GO:0005615=PMID:6793628, GO:0051787=PMID:18725990, GO:0051788=PMID:18725990, GO:0016485=PMID:18725990, GO:0010756=PMID:89876, GO:0007596=Reactome:REACT_2051, GO:0030194=PMID:6793628, GO:0045087=PMID:2510163, GO:0002542=PMID:18725990, GO:0007597=PMID:18725990, GO:0006508=GO_REF:0000037, GO:0002353=PMID:18725990, GO:0042730=GO_REF:0000037, GO:0070009=GO_REF:0000019, GO:0031638=PMID:89876} P00748 Coagulation factor XII protein 20081015 {GO:0005515=IPI, GO:0016540=IDA, GO:0005886=TAS, GO:0004252=IDA, GO:0051919=IDA, GO:0005576=TAS, GO:0005615=IDA, GO:0051787=IC, GO:0051788=IDA, GO:0016485=IDA, GO:0010756=IDA, GO:0007596=TAS, GO:0030194=IDA, GO:0045087=TAS, GO:0002542=IDA, GO:0007597=IC, GO:0006508=IEA, GO:0002353=IDA, GO:0042730=IEA, GO:0070009=IEA, GO:0031638=IDA} Factor XII activation, blood coagulation, blood coagulation, intrinsic pathway, fibrinolysis, innate immune response, plasma kallikrein-kinin cascade, positive regulation of blood coagulation, positive regulation of fibrinolysis, positive regulation of plasminogen activation, protein autoprocessing, protein processing, proteolysis, response to misfolded protein, zymogen activation extracellular region, extracellular space, plasma membrane misfolded protein binding, protein binding, serine-type aminopeptidase activity, serine-type endopeptidase activity Human F13A1 ENSEMBL UniProtKB {GO:0018149=GO_REF:0000019, GO:0007596=GO_REF:0000019, GO:0003810=GO_REF:0000019, GO:0002576=Reactome:REACT_318, GO:0030168=Reactome:REACT_798, GO:0031093=Reactome:REACT_21351, GO:0005576=Reactome:REACT_21351, GO:0046872=GO_REF:0000037} Q9NQP5 Coagulation factor XIII A chain protein 20130413 {GO:0018149=IEA, GO:0007596=IEA, GO:0003810=IEA, GO:0002576=TAS, GO:0030168=TAS, GO:0031093=TAS, GO:0005576=TAS, GO:0046872=IEA} blood coagulation, peptide cross-linking, platelet activation, platelet degranulation extracellular region, platelet alpha granule lumen metal ion binding, protein-glutamine gamma-glutamyltransferase activity Human Ensembl:ENSMUSP00000048667 F13B Reactome UniProtKB {GO:0007596=Reactome:REACT_2051, GO:0005576=Reactome:REACT_1314} P05160 Coagulation factor XIII B chain protein 20040824 {GO:0007596=TAS, GO:0005576=TAS} blood coagulation extracellular region Human F2 BHF-UCL UniProtKB {GO:0010544=PMID:17379830, GO:0005515=PMID:8626514, GO:0008284=GO_REF:0000019, GO:0004252=PMID:1672265, GO:0005886=Reactome:REACT_1834, GO:0030307=GO_REF:0000019, GO:0008360=GO_REF:0000019, GO:1900738=PMID:20164183, GO:0050900=Reactome:REACT_12051, GO:0005615=PMID:9639571, GO:0006508=Reactome:REACT_733, GO:0051281=PMID:1672265, GO:0005796=Reactome:REACT_1065, GO:0051480=PMID:19052258, GO:0005509=GO_REF:0000002, GO:0009611=PMID:9639571, GO:0005102=PMID:8626514, GO:0051918=PMID:17379830, GO:0030168=PMID:9038223, GO:0014068=GO_REF:0000019, GO:0005576=Reactome:REACT_23955, GO:0007275=PMID:9639571, GO:0006953=GO_REF:0000037, GO:0045861=PMID:1695900, GO:0048712=PMID:1691280, GO:0017187=Reactome:REACT_1132, GO:0032967=PMID:9639571, GO:0030193=PMID:12855810, GO:0030194=PMID:9038223, GO:0007596=Reactome:REACT_2051, GO:0007597=Reactome:REACT_326, GO:0001934=PMID:7559487, GO:0005788=Reactome:REACT_903, GO:0008083=PMID:8626514, GO:2000379=PMID:17275676, GO:0044267=Reactome:REACT_17015, GO:0042730=PMID:12855810, GO:0007166=PMID:1672265, GO:0070053=PMID:2435757, GO:0043687=Reactome:REACT_22161} P00734 Prothrombin protein 20100329 {GO:0010544=TAS, GO:0005515=IPI, GO:0008284=IEA, GO:0004252=IDA, GO:0005886=TAS, GO:0030307=IEA, GO:0008360=IEA, GO:1900738=IDA, GO:0050900=TAS, GO:0005615=IDA, GO:0006508=TAS, GO:0051281=IDA, GO:0005796=TAS, GO:0051480=IDA, GO:0005509=IEA, GO:0009611=IDA, GO:0005102=IPI, GO:0051918=TAS, GO:0030168=IDA, GO:0014068=IEA, GO:0005576=TAS, GO:0007275=TAS, GO:0006953=IEA, GO:0045861=IDA, GO:0048712=IDA, GO:0017187=TAS, GO:0032967=IDA, GO:0030193=TAS, GO:0030194=IDA, GO:0007596=TAS, GO:0007597=TAS, GO:0001934=IDA, GO:0005788=TAS, GO:0008083=TAS, GO:2000379=IDA, GO:0044267=TAS, GO:0042730=IDA, GO:0007166=IDA, GO:0070053=IDA, GO:0043687=TAS} acute-phase response, blood coagulation, blood coagulation, intrinsic pathway, cell surface receptor signaling pathway, cellular protein metabolic process, cytosolic calcium ion homeostasis, fibrinolysis, leukocyte migration, multicellular organismal development, negative regulation of astrocyte differentiation, negative regulation of fibrinolysis, negative regulation of platelet activation, negative regulation of proteolysis, peptidyl-glutamic acid carboxylation, platelet activation, positive regulation of blood coagulation, positive regulation of cell growth, positive regulation of cell proliferation, positive regulation of collagen biosynthetic process, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway, positive regulation of protein phosphorylation, positive regulation of reactive oxygen species metabolic process, positive regulation of release of sequestered calcium ion into cytosol, post-translational protein modification, proteolysis, regulation of blood coagulation, regulation of cell shape, response to wounding Golgi lumen, endoplasmic reticulum lumen, extracellular region, extracellular space, plasma membrane calcium ion binding, growth factor activity, protein binding, receptor binding, serine-type endopeptidase activity, thrombospondin receptor activity Human F2R BHF-UCL UniProtKB {GO:0005515=PMID:17848177, GO:0031594=GO_REF:0000024, GO:0051928=GO_REF:0000024, GO:0009653=PMID:9701242, GO:0043524=GO_REF:0000024, GO:0045211=GO_REF:0000024, GO:0051482=GO_REF:0000024, GO:0032496=GO_REF:0000024, GO:0070374=GO_REF:0000024, GO:0043123=PMID:12761501, GO:2000484=PMID:17404307, GO:0031681=GO_REF:0000024, GO:0030335=PMID:9701242, GO:0051209=GO_REF:0000024, GO:0005794=PMID:7961693, GO:0004930=PMID:17848177, GO:0030168=PMID:9038223, GO:0014068=GO_REF:0000024, GO:0043280=PMID:10692450, GO:0032967=PMID:9639571, GO:0007186=GO_REF:0000024, GO:0005887=PMID:1672265, GO:0045893=PMID:17848177, GO:0051930=GO_REF:0000024, GO:0007260=PMID:10692450, GO:0008284=GO_REF:0000024, GO:0008285=PMID:10692450, GO:0005886=PMID:9038223, GO:0015057=PMID:1672265, GO:0035025=GO_REF:0000024, GO:0007262=PMID:10692450, GO:0007200=PMID:20164183, GO:0007204=GO_REF:0000024, GO:0007205=GO_REF:0000024, GO:0001965=GO_REF:0000024, GO:0000186=GO_REF:0000024, GO:0048873=GO_REF:0000024, GO:0006954=GO_REF:0000024, GO:0045907=GO_REF:0000024, GO:0007529=GO_REF:0000024, GO:0045987=GO_REF:0000024, GO:2000778=PMID:11447194, GO:0031094=PMID:9038223, GO:0051281=PMID:1672265, GO:0006919=PMID:10692450, GO:0005102=PMID:1672265, GO:0009611=PMID:9639571, GO:0002248=PMID:9639571, GO:0005576=Reactome:REACT_72, GO:0003105=GO_REF:0000024, GO:0046427=PMID:10692450, GO:0030193=PMID:17848177, GO:0030194=PMID:9038223, GO:0007596=Reactome:REACT_604, GO:0005901=PMID:17848177, GO:0060155=PMID:1672265, GO:1900134=GO_REF:0000024, GO:0043410=PMID:17848177, GO:0032651=GO_REF:0000024} P25116 Proteinase-activated receptor 1 protein 20100624 {GO:0005515=IPI, GO:0031594=ISS, GO:0051928=ISS, GO:0009653=TAS, GO:0043524=ISS, GO:0045211=ISS, GO:0051482=ISS, GO:0032496=ISS, GO:0070374=ISS, GO:0043123=IEP, GO:2000484=IDA, GO:0031681=ISS, GO:0030335=IMP, GO:0051209=ISS, GO:0005794=TAS, GO:0004930=TAS, GO:0030168=IDA, GO:0014068=ISS, GO:0043280=IDA, GO:0032967=IDA, GO:0007186=ISS, GO:0005887=TAS, GO:0045893=IDA, GO:0051930=ISS, GO:0007260=IDA, GO:0008284=ISS, GO:0008285=IDA, GO:0005886=IDA, GO:0015057=IDA, GO:0035025=ISS, GO:0007262=IDA, GO:0007200=IDA, GO:0007204=ISS, GO:0007205=ISS, GO:0001965=ISS, GO:0000186=ISS, GO:0048873=ISS, GO:0006954=ISS, GO:0045907=ISS, GO:0007529=ISS, GO:0045987=ISS, GO:2000778=IDA, GO:0031094=IDA, GO:0051281=IDA, GO:0006919=IDA, GO:0005102=IPI, GO:0009611=IDA, GO:0002248=IDA, GO:0005576=TAS, GO:0003105=ISS, GO:0046427=IDA, GO:0030193=IDA, GO:0030194=IDA, GO:0007596=TAS, GO:0005901=IDA, GO:0060155=IC, GO:1900134=ISS, GO:0043410=IDA, GO:0032651=ISS} G-protein coupled receptor signaling pathway, STAT protein import into nucleus, activation of MAPKK activity, activation of cysteine-type endopeptidase activity involved in apoptotic process, anatomical structure morphogenesis, blood coagulation, connective tissue replacement involved in inflammatory response wound healing, elevation of cytosolic calcium ion concentration, elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway, establishment of synaptic specificity at neuromuscular junction, homeostasis of number of cells within a tissue, inflammatory response, negative regulation of cell proliferation, negative regulation of glomerular filtration, negative regulation of neuron apoptotic process, negative regulation of renin secretion into blood stream, phospholipase C-activating G-protein coupled receptor signaling pathway, platelet activation, platelet dense granule organization, positive regulation of ERK1 and ERK2 cascade, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of JAK-STAT cascade, positive regulation of MAPK cascade, positive regulation of Rho protein signal transduction, positive regulation of blood coagulation, positive regulation of calcium ion transport, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of collagen biosynthetic process, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of interleukin-6 secretion, positive regulation of interleukin-8 secretion, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of release of sequestered calcium ion into cytosol, positive regulation of smooth muscle contraction, positive regulation of transcription, DNA-dependent, positive regulation of vasoconstriction, protein kinase C-activating G-protein coupled receptor signaling pathway, regulation of blood coagulation, regulation of interleukin-1 beta production, regulation of sensory perception of pain, release of sequestered calcium ion into cytosol, response to lipopolysaccharide, response to wounding, tyrosine phosphorylation of STAT protein Golgi apparatus, caveola, extracellular region, integral to plasma membrane, neuromuscular junction, plasma membrane, platelet dense tubular network, postsynaptic membrane G-protein alpha-subunit binding, G-protein beta-subunit binding, G-protein coupled receptor activity, protein binding, receptor binding, thrombin receptor activity Human GO:0051281 F2RL1 BHF-UCL UniProtKB {GO:0005515=PMID:20826780, GO:0043311=PMID:11714832, GO:0070963=PMID:21501162, GO:0046330=PMID:11413129, GO:0050900=PMID:15155775, GO:0060100=PMID:21501162, GO:0046328=PMID:16410250, GO:0051607=PMID:19494303, GO:0046329=PMID:19781631, GO:0030836=PMID:17500066, GO:0031274=GO_REF:0000024, GO:0070374=GO_REF:0000024, GO:0043123=PMID:11413129, GO:0090195=PMID:19494303, GO:0043122=PMID:18453611, GO:0090198=PMID:19865078, GO:2000484=PMID:19865078, GO:0072608=PMID:18453611, GO:0031681=GO_REF:0000024, GO:0005794=PMID:8615752, GO:0030335=GO_REF:0000024, GO:0004930=PMID:18622013, GO:0050702=PMID:15155775, GO:0014068=GO_REF:0000024, GO:0010804=PMID:19781631, GO:0072643=GO_REF:0000024, GO:0007186=PMID:7556175, GO:0005887=PMID:17848177, GO:0045087=GO_REF:0000037, GO:0042119=PMID:15155775, GO:0034145=PMID:18622013, GO:0005886=Reactome:REACT_22436, GO:0034141=PMID:19865078, GO:0034140=PMID:19865078, GO:0015057=GO_REF:0000002, GO:0035025=GO_REF:0000024, GO:0035926=PMID:21501162, GO:0097029=GO_REF:0000024, GO:0007204=GO_REF:0000024, GO:0050927=PMID:17991872, GO:0031143=GO_REF:0000024, GO:0001965=GO_REF:0000024, GO:0006954=GO_REF:0000037, GO:0050921=GO_REF:0000024, GO:0061028=PMID:20826780, GO:0045909=GO_REF:0000024, GO:2000778=PMID:11447194, GO:0045944=PMID:16410250, GO:0004872=PMID:8615752, GO:0034137=PMID:19865078, GO:0032930=PMID:11714832, GO:0002286=GO_REF:0000024, GO:0005102=PMID:8615752, GO:0003104=GO_REF:0000024, GO:0002690=PMID:17991872, GO:0002741=PMID:11441110, GO:0030193=PMID:17848177, GO:0007596=GO_REF:0000002, GO:0070661=GO_REF:0000024, GO:0016021=GO_REF:0000002, GO:1900135=GO_REF:0000024} P55085 Proteinase-activated receptor 2 protein 20080215 {GO:0005515=IPI, GO:0043311=IDA, GO:0070963=IDA, GO:0046330=IDA, GO:0050900=IDA, GO:0060100=IDA, GO:0046328=IDA, GO:0051607=IDA, GO:0046329=IDA, GO:0030836=IDA, GO:0031274=ISS, GO:0070374=ISS, GO:0043123=IDA, GO:0090195=IDA, GO:0043122=IDA, GO:0090198=IDA, GO:2000484=IDA, GO:0072608=IDA, GO:0031681=ISS, GO:0005794=TAS, GO:0030335=ISS, GO:0004930=IMP, GO:0050702=IDA, GO:0014068=ISS, GO:0010804=IDA, GO:0072643=ISS, GO:0007186=TAS, GO:0005887=IDA, GO:0045087=IEA, GO:0042119=IDA, GO:0034145=IDA, GO:0005886=TAS, GO:0034141=IMP, GO:0034140=IMP, GO:0015057=IEA, GO:0035025=ISS, GO:0035926=IDA, GO:0097029=ISS, GO:0007204=ISS, GO:0050927=IDA, GO:0031143=ISS, GO:0001965=ISS, GO:0006954=IEA, GO:0050921=ISS, GO:0061028=IDA, GO:0045909=ISS, GO:2000778=IDA, GO:0045944=IDA, GO:0004872=TAS, GO:0034137=IMP, GO:0032930=IDA, GO:0002286=ISS, GO:0005102=TAS, GO:0003104=ISS, GO:0002690=IDA, GO:0002741=IDA, GO:0030193=IDA, GO:0007596=IEA, GO:0070661=ISS, GO:0016021=IEA, GO:1900135=ISS} G-protein coupled receptor signaling pathway, T cell activation involved in immune response, blood coagulation, chemokine (C-C motif) ligand 2 secretion, chemokine secretion, defense response to virus, elevation of cytosolic calcium ion concentration, establishment of endothelial barrier, inflammatory response, innate immune response, interferon-gamma secretion, interleukin-1 beta secretion, interleukin-10 secretion, leukocyte migration, leukocyte proliferation, mature dendritic cell differentiation, negative regulation of JNK cascade, negative regulation of chemokine secretion, negative regulation of toll-like receptor 3 signaling pathway, negative regulation of tumor necrosis factor-mediated signaling pathway, neutrophil activation, positive regulation of ERK1 and ERK2 cascade, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of JNK cascade, positive regulation of Rho protein signal transduction, positive regulation of actin filament depolymerization, positive regulation of cell migration, positive regulation of chemotaxis, positive regulation of cytokine secretion involved in immune response, positive regulation of eosinophil degranulation, positive regulation of glomerular filtration, positive regulation of interleukin-6 secretion, positive regulation of interleukin-8 secretion, positive regulation of leukocyte chemotaxis, positive regulation of neutrophil mediated killing of gram-negative bacterium, positive regulation of phagocytosis, engulfment, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of positive chemotaxis, positive regulation of pseudopodium assembly, positive regulation of renin secretion into blood stream, positive regulation of superoxide anion generation, positive regulation of toll-like receptor 2 signaling pathway, positive regulation of toll-like receptor 3 signaling pathway, positive regulation of toll-like receptor 4 signaling pathway, positive regulation of transcription from RNA polymerase II promoter, positive regulation of vasodilation, regulation of I-kappaB kinase/NF-kappaB cascade, regulation of JNK cascade, regulation of blood coagulation Golgi apparatus, integral to membrane, integral to plasma membrane, plasma membrane, pseudopodium G-protein alpha-subunit binding, G-protein beta-subunit binding, G-protein coupled receptor activity, protein binding, receptor activity, receptor binding, thrombin receptor activity Human F2RL2 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0016324=GO_REF:0000019, GO:0005886=Reactome:REACT_23902, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:9087410, GO:0004435=PMID:9087410, GO:0015057=GO_REF:0000002, GO:0009611=PMID:9087410, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_72} O00254 Proteinase-activated receptor 3 protein 20130415 {GO:0005515=IPI, GO:0016324=IEA, GO:0005886=TAS, GO:0007596=TAS, GO:0005887=TAS, GO:0004435=TAS, GO:0015057=IEA, GO:0009611=TAS, GO:0030168=TAS, GO:0005576=TAS} blood coagulation, platelet activation, response to wounding apical plasma membrane, extracellular region, integral to plasma membrane, plasma membrane phosphatidylinositol phospholipase C activity, protein binding, thrombin receptor activity Human UniProtKB:P16333 F2RL3 BHF-UCL UniProtKB {GO:0007165=PMID:9618465, GO:0005886=Reactome:REACT_23902, GO:0005887=PMID:9618465, GO:0015057=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0009611=PMID:9618465, GO:0030168=Reactome:REACT_798, GO:0007200=PMID:9618465, GO:0060155=PMID:18480058, GO:0005576=Reactome:REACT_72, GO:0016021=GO_REF:0000002, GO:0051281=PMID:18480058} Q96RI0 Proteinase-activated receptor 4 protein 20100624 {GO:0007165=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0015057=IEA, GO:0007596=TAS, GO:0009611=TAS, GO:0030168=TAS, GO:0007200=TAS, GO:0060155=IC, GO:0005576=TAS, GO:0016021=IEA, GO:0051281=IDA} blood coagulation, phospholipase C-activating G-protein coupled receptor signaling pathway, platelet activation, platelet dense granule organization, positive regulation of release of sequestered calcium ion into cytosol, response to wounding, signal transduction extracellular region, integral to membrane, integral to plasma membrane, plasma membrane thrombin receptor activity Human GO:0051281 F3 BHF-UCL UniProtKB {GO:0005515=PMID:20634491, GO:0051897=PMID:18612547, GO:0043498=PMID:17898544, GO:0043066=PMID:18612547, GO:0030335=PMID:18612547, GO:0005886=Reactome:REACT_1669, GO:0006919=PMID:17898544, GO:0002543=PMID:17469850, GO:0002020=PMID:3455766, GO:0005615=PMID:19065458, GO:0045766=PMID:17898544, GO:0031233=PMID:17469850, GO:0050927=PMID:17991872, GO:0031012=PMID:2704749, GO:0005543=PMID:17469850, GO:0001938=PMID:17898544, GO:0007596=Reactome:REACT_2051, GO:0007598=Reactome:REACT_1573, GO:0002541=PMID:17469850, GO:0010641=PMID:17991872, GO:0016021=GO_REF:0000037} P13726 Tissue factor protein 20090416 {GO:0005515=IPI, GO:0051897=IMP, GO:0043498=IDA, GO:0043066=TAS, GO:0030335=TAS, GO:0005886=TAS, GO:0006919=IDA, GO:0002543=IC, GO:0002020=IPI, GO:0005615=IDA, GO:0045766=IDA, GO:0031233=IC, GO:0050927=IC, GO:0031012=IDA, GO:0005543=IDA, GO:0001938=IDA, GO:0007596=TAS, GO:0007598=TAS, GO:0002541=IDA, GO:0010641=IDA, GO:0016021=IEA} activation of blood coagulation via clotting cascade, activation of cysteine-type endopeptidase activity involved in apoptotic process, activation of plasma proteins involved in acute inflammatory response, blood coagulation, blood coagulation, extrinsic pathway, negative regulation of apoptotic process, positive regulation of angiogenesis, positive regulation of cell migration, positive regulation of endothelial cell proliferation, positive regulation of platelet-derived growth factor receptor signaling pathway, positive regulation of positive chemotaxis, positive regulation of protein kinase B signaling cascade extracellular matrix, extracellular space, integral to membrane, intrinsic to external side of plasma membrane, plasma membrane cell surface binding, phospholipid binding, protease binding, protein binding Human F5 Reactome UniProtKB {GO:0005515=PMID:9556620, GO:0005886=Reactome:REACT_1446, GO:0007596=Reactome:REACT_2051, GO:0005507=GO_REF:0000002, GO:0008015=GO_REF:0000019, GO:0002576=Reactome:REACT_318, GO:0030168=Reactome:REACT_798, GO:0031093=Reactome:REACT_21351, GO:0005576=Reactome:REACT_21351, GO:0007155=GO_REF:0000002, GO:0005615=GO_REF:0000019} P12259 Coagulation factor V protein 20040824 {GO:0005515=IPI, GO:0005886=TAS, GO:0007596=TAS, GO:0005507=IEA, GO:0008015=IEA, GO:0002576=TAS, GO:0030168=TAS, GO:0031093=TAS, GO:0005576=TAS, GO:0007155=IEA, GO:0005615=IEA} blood circulation, blood coagulation, cell adhesion, platelet activation, platelet degranulation extracellular region, extracellular space, plasma membrane, platelet alpha granule lumen copper ion binding, protein binding Human F7 BHF-UCL UniProtKB {GO:0051897=PMID:18612547, GO:0043627=GO_REF:0000019, GO:0004252=GO_REF:0000002, GO:0005886=Reactome:REACT_1669, GO:0031100=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0050927=PMID:17991872, GO:0001948=PMID:3455766, GO:0006508=Reactome:REACT_733, GO:0010641=PMID:17991872, GO:0043066=PMID:18612547, GO:0060416=GO_REF:0000019, GO:0030335=PMID:18612547, GO:0005796=Reactome:REACT_1743, GO:0005509=GO_REF:0000002, GO:0005102=GO_REF:0000019, GO:0005576=Reactome:REACT_1669, GO:0031982=GO_REF:0000019, GO:0002690=PMID:17991872, GO:0017187=Reactome:REACT_1132, GO:0030194=GO_REF:0000019, GO:0007596=Reactome:REACT_2051, GO:0007598=Reactome:REACT_1573, GO:0008236=PMID:3037537, GO:0005788=Reactome:REACT_1969, GO:0007623=GO_REF:0000019, GO:0032571=GO_REF:0000019, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} P08709 Coagulation factor VII protein 20090416 {GO:0051897=IDA, GO:0043627=IEA, GO:0004252=IEA, GO:0005886=TAS, GO:0031100=IEA, GO:0005615=IEA, GO:0050927=IDA, GO:0001948=IPI, GO:0006508=TAS, GO:0010641=IDA, GO:0043066=TAS, GO:0060416=IEA, GO:0030335=TAS, GO:0005796=TAS, GO:0005509=IEA, GO:0005102=IEA, GO:0005576=TAS, GO:0031982=IEA, GO:0002690=IDA, GO:0017187=TAS, GO:0030194=IEA, GO:0007596=TAS, GO:0007598=TAS, GO:0008236=TAS, GO:0005788=TAS, GO:0007623=IEA, GO:0032571=IEA, GO:0044267=TAS, GO:0043687=TAS} blood coagulation, blood coagulation, extrinsic pathway, cellular protein metabolic process, circadian rhythm, negative regulation of apoptotic process, organ regeneration, peptidyl-glutamic acid carboxylation, positive regulation of blood coagulation, positive regulation of cell migration, positive regulation of leukocyte chemotaxis, positive regulation of platelet-derived growth factor receptor signaling pathway, positive regulation of positive chemotaxis, positive regulation of protein kinase B signaling cascade, post-translational protein modification, proteolysis, response to estrogen stimulus, response to growth hormone stimulus, response to vitamin K Golgi lumen, endoplasmic reticulum lumen, extracellular region, extracellular space, plasma membrane, vesicle calcium ion binding, glycoprotein binding, receptor binding, serine-type endopeptidase activity, serine-type peptidase activity Human F8 Reactome UniProtKB {GO:0005515=PMID:7756647, GO:0005886=Reactome:REACT_1668, GO:0005507=GO_REF:0000002, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_21351, GO:0006953=GO_REF:0000037, GO:0005615=GO_REF:0000039, GO:0007596=Reactome:REACT_2051, GO:0007597=Reactome:REACT_326, GO:0002576=Reactome:REACT_318, GO:0016491=GO_REF:0000002, GO:0031093=Reactome:REACT_21351, GO:0007155=GO_REF:0000002} P00451 Coagulation factor VIII protein 20050120 {GO:0005515=IPI, GO:0005886=TAS, GO:0005507=IEA, GO:0030168=TAS, GO:0005576=TAS, GO:0006953=IEA, GO:0005615=IEA, GO:0007596=TAS, GO:0007597=TAS, GO:0002576=TAS, GO:0016491=IEA, GO:0031093=TAS, GO:0007155=IEA} acute-phase response, blood coagulation, blood coagulation, intrinsic pathway, cell adhesion, platelet activation, platelet degranulation extracellular region, extracellular space, plasma membrane, platelet alpha granule lumen copper ion binding, oxidoreductase activity, protein binding Human F8A1 LIFEdb UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005634=GO_REF:0000054} P23610 Factor VIII intron 22 protein protein 20100607 {GO:0008150=ND, GO:0003674=ND, GO:0005634=IDA} biological_process nucleus molecular_function Human F9 UniProtKB UniProtKB {GO:0004252=GO_REF:0000002, GO:0005886=Reactome:REACT_1668, GO:0005796=Reactome:REACT_618, GO:0005509=GO_REF:0000002, GO:0005576=GO_REF:0000002, GO:0017187=Reactome:REACT_1132, GO:0007596=GO_REF:0000002, GO:0007597=Reactome:REACT_326, GO:0007598=Reactome:REACT_1573, GO:0006508=GO_REF:0000038, GO:0005788=Reactome:REACT_2045, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q5FBE1 Coagulation factor IX protein 20130413 {GO:0004252=IEA, GO:0005886=TAS, GO:0005796=TAS, GO:0005509=IEA, GO:0005576=IEA, GO:0017187=TAS, GO:0007596=IEA, GO:0007597=TAS, GO:0007598=TAS, GO:0006508=IEA, GO:0005788=TAS, GO:0044267=TAS, GO:0043687=TAS} blood coagulation, blood coagulation, extrinsic pathway, blood coagulation, intrinsic pathway, cellular protein metabolic process, peptidyl-glutamic acid carboxylation, post-translational protein modification, proteolysis Golgi lumen, endoplasmic reticulum lumen, extracellular region, plasma membrane calcium ion binding, serine-type endopeptidase activity Human UniProtKB-KW:KW-0645 FA2H UniProtKB UniProtKB {GO:0006665=GO_REF:0000002, GO:0008219=GO_REF:0000037, GO:0042634=GO_REF:0000019, GO:0005506=GO_REF:0000002, GO:0005783=GO_REF:0000019, GO:0032287=GO_REF:0000019, GO:0046872=GO_REF:0000038, GO:0001949=GO_REF:0000019, GO:0032286=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0006633=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0022900=GO_REF:0000037, GO:0030258=GO_REF:0000019, GO:0080132=GO_REF:0000019, GO:0020037=GO_REF:0000002} Q7L5A8 Fatty acid 2-hydroxylase protein 20130413 {GO:0006665=IEA, GO:0008219=IEA, GO:0042634=IEA, GO:0005506=IEA, GO:0005783=IEA, GO:0032287=IEA, GO:0046872=IEA, GO:0001949=IEA, GO:0032286=IEA, GO:0042127=IEA, GO:0005789=IEA, GO:0006633=IEA, GO:0016021=IEA, GO:0022900=IEA, GO:0030258=IEA, GO:0080132=IEA, GO:0020037=IEA} cell death, central nervous system myelin maintenance, electron transport chain, fatty acid biosynthetic process, lipid modification, peripheral nervous system myelin maintenance, regulation of cell proliferation, regulation of hair cycle, sebaceous gland cell differentiation, sphingolipid metabolic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane fatty acid alpha-hydroxylase activity, heme binding, iron ion binding, metal ion binding Human UniProtKB-SubCell:SL-0097 FAAH HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0016884=GO_REF:0000002, GO:0017064=PMID:9122178, GO:0031090=GO_REF:0000024, GO:0047372=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0005856=GO_REF:0000039, GO:0009062=PMID:9122178, GO:0012505=GO_REF:0000039} O00519 Fatty-acid amide hydrolase 1 protein 20080205 {GO:0005737=IDA, GO:0016884=IEA, GO:0017064=IDA, GO:0031090=ISS, GO:0047372=IEA, GO:0016021=IEA, GO:0005856=IEA, GO:0009062=IDA, GO:0012505=IEA} fatty acid catabolic process cytoplasm, cytoskeleton, endomembrane system, integral to membrane, organelle membrane acylglycerol lipase activity, carbon-nitrogen ligase activity, with glutamine as amido-N-donor, fatty acid amide hydrolase activity Human FAAH2 UniProtKB UniProtKB {GO:0016884=GO_REF:0000002, GO:0016787=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q6GMR7 Fatty-acid amide hydrolase 2 protein 20130413 {GO:0016884=IEA, GO:0016787=IEA, GO:0016021=IEA} integral to membrane carbon-nitrogen ligase activity, with glutamine as amido-N-donor, hydrolase activity Human UniProtKB-KW:KW-0378 FABP1 Reactome UniProtKB {GO:0005215=GO_REF:0000002, GO:0043066=PMID:16175609, GO:0005504=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0032052=GO_REF:0000019, GO:0016209=PMID:16175609, GO:0070301=PMID:16175609, GO:0005782=GO_REF:0000024, GO:0051345=GO_REF:0000019, GO:0005324=GO_REF:0000019, GO:0071456=PMID:16175609, GO:0044281=Reactome:REACT_111217, GO:0008289=GO_REF:0000038, GO:0005829=GO_REF:0000019, GO:0050892=GO_REF:0000019, GO:0005543=GO_REF:0000019, GO:0045179=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0008144=GO_REF:0000019, GO:0032000=GO_REF:0000019, GO:0005654=Reactome:REACT_115721, GO:0043154=PMID:16175609, GO:0044255=Reactome:REACT_22279} P07148 Fatty acid-binding protein, liver protein 20111113 {GO:0005215=IEA, GO:0043066=IDA, GO:0005504=IEA, GO:0008284=IEA, GO:0032052=IEA, GO:0016209=IDA, GO:0070301=IDA, GO:0005782=ISS, GO:0051345=IEA, GO:0005324=IEA, GO:0071456=IDA, GO:0044281=TAS, GO:0008289=IEA, GO:0005829=IEA, GO:0050892=IEA, GO:0005543=IEA, GO:0045179=IEA, GO:0003682=IEA, GO:0008144=IEA, GO:0032000=IEA, GO:0005654=TAS, GO:0043154=IDA, GO:0044255=TAS} cellular lipid metabolic process, cellular response to hydrogen peroxide, cellular response to hypoxia, intestinal absorption, negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of cell proliferation, positive regulation of fatty acid beta-oxidation, positive regulation of hydrolase activity, small molecule metabolic process apical cortex, cytosol, nucleoplasm, peroxisomal matrix antioxidant activity, bile acid binding, chromatin binding, drug binding, fatty acid binding, lipid binding, long-chain fatty acid transporter activity, phospholipid binding, transporter activity Human FABP2 PINC UniProtKB {GO:0005902=GO_REF:0000019, GO:0050892=GO_REF:0000019, GO:0005504=GO_REF:0000019, GO:0045179=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0005324=GO_REF:0000019, GO:0007586=PMID:7883976, GO:0006631=GO_REF:0000019} P12104 Fatty acid-binding protein, intestinal protein 20030904 {GO:0005902=IEA, GO:0050892=IEA, GO:0005504=IEA, GO:0045179=IEA, GO:0005886=IEA, GO:0005324=IEA, GO:0007586=TAS, GO:0006631=IEA} digestion, fatty acid metabolic process, intestinal absorption apical cortex, microvillus, plasma membrane fatty acid binding, long-chain fatty acid transporter activity Human FABP3 PINC UniProtKB {GO:0008092=PMID:17987659, GO:0032868=GO_REF:0000019, GO:0016528=GO_REF:0000019, GO:0008285=PMID:7962070, GO:0070542=GO_REF:0000019, GO:0005324=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0006631=GO_REF:0000019, GO:0050543=GO_REF:0000019, GO:0008289=PMID:3421901, GO:0005829=GO_REF:0000019} P05413 Fatty acid-binding protein, heart protein 20030904 {GO:0008092=IPI, GO:0032868=IEA, GO:0016528=IEA, GO:0008285=TAS, GO:0070542=IEA, GO:0005324=IEA, GO:0042493=IEA, GO:0006631=IEA, GO:0050543=IEA, GO:0008289=TAS, GO:0005829=IEA} fatty acid metabolic process, negative regulation of cell proliferation, response to drug, response to fatty acid, response to insulin stimulus cytosol, sarcoplasm cytoskeletal protein binding, icosatetraenoic acid binding, lipid binding, long-chain fatty acid transporter activity Human FABP4 HPA UniProtKB {GO:0006629=Reactome:REACT_602, GO:0042632=GO_REF:0000019, GO:0071285=GO_REF:0000019, GO:0005811=Reactome:REACT_27226, GO:0005215=GO_REF:0000002, GO:0005504=PMID:2481498, GO:0005634=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0001816=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0050872=GO_REF:0000019, GO:0050873=GO_REF:0000019, GO:0050729=GO_REF:0000019, GO:0019433=Reactome:REACT_494, GO:0006469=GO_REF:0000019, GO:0045892=GO_REF:0000019} P15090 Fatty acid-binding protein, adipocyte protein 20100326 {GO:0006629=TAS, GO:0042632=IEA, GO:0071285=IEA, GO:0005811=TAS, GO:0005215=IEA, GO:0005504=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0001816=IEA, GO:0005737=IDA, GO:0050872=IEA, GO:0050873=IEA, GO:0050729=IEA, GO:0019433=TAS, GO:0006469=IEA, GO:0045892=IEA} brown fat cell differentiation, cellular response to lithium ion, cholesterol homeostasis, cytokine production, lipid metabolic process, negative regulation of protein kinase activity, negative regulation of transcription, DNA-dependent, positive regulation of inflammatory response, small molecule metabolic process, triglyceride catabolic process, white fat cell differentiation cytoplasm, lipid particle, nucleus fatty acid binding, transporter activity Human FABP5 PINC UniProtKB {GO:0006629=PMID:8092987, GO:0005515=PMID:12839573, GO:0005215=GO_REF:0000002, GO:0005504=PMID:8092987, GO:0005737=PMID:16130169, GO:0008544=PMID:1512466, GO:0015758=GO_REF:0000019, GO:0006006=GO_REF:0000019, GO:0006656=GO_REF:0000019, GO:0008289=PMID:1512466} Q01469 Fatty acid-binding protein, epidermal protein 20030904 {GO:0006629=TAS, GO:0005515=IPI, GO:0005215=IEA, GO:0005504=TAS, GO:0005737=TAS, GO:0008544=TAS, GO:0015758=IEA, GO:0006006=IEA, GO:0006656=IEA, GO:0008289=TAS} epidermis development, glucose metabolic process, glucose transport, lipid metabolic process, phosphatidylcholine biosynthetic process cytoplasm fatty acid binding, lipid binding, protein binding, transporter activity Human FABP6 HPA UniProtKB {GO:0006629=PMID:9250612, GO:0005215=GO_REF:0000002, GO:0005737=PMID:7588781, GO:0005794=GO_REF:0000052, GO:0008285=PMID:9250612, GO:0015721=Reactome:REACT_11042, GO:0005634=GO_REF:0000052, GO:0008206=Reactome:REACT_11040, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_10078, GO:0008289=GO_REF:0000037} P51161 Gastrotropin protein 20090616 {GO:0006629=NAS, GO:0005215=IEA, GO:0005737=TAS, GO:0005794=IDA, GO:0008285=TAS, GO:0015721=TAS, GO:0005634=IDA, GO:0008206=TAS, GO:0044281=TAS, GO:0005829=TAS, GO:0008289=IEA} bile acid and bile salt transport, bile acid metabolic process, lipid metabolic process, negative regulation of cell proliferation, small molecule metabolic process Golgi apparatus, cytoplasm, cytosol, nucleus lipid binding, transporter activity Human FABP9 ENSEMBL UniProtKB {GO:0001675=GO_REF:0000019, GO:0005215=GO_REF:0000002, GO:0001669=GO_REF:0000019, GO:0008289=GO_REF:0000037} Q0Z7S8 Fatty acid-binding protein 9 protein 20130413 {GO:0001675=IEA, GO:0005215=IEA, GO:0001669=IEA, GO:0008289=IEA} acrosome assembly acrosomal vesicle lipid binding, transporter activity Human Ensembl:ENSRNOP00000014949 FADD BHF-UCL UniProtKB {GO:0005515=PMID:16127453, GO:0008625=PMID:7538907, GO:0043005=GO_REF:0000019, GO:0034142=Reactome:REACT_6894, GO:0031265=PMID:20935634, GO:0031264=PMID:11101870, GO:0032813=PMID:21109225, GO:0097202=PMID:18387192, GO:0002020=PMID:9208847, GO:0051291=GO_REF:0000019, GO:0032757=PMID:16127453, GO:0042802=PMID:8681376, GO:0005829=Reactome:REACT_150447, GO:0002756=Reactome:REACT_6809, GO:0051607=PMID:21109225, GO:0045944=PMID:16127453, GO:0043123=PMID:12761501, GO:0034138=Reactome:REACT_6783, GO:0005164=GO_REF:0000019, GO:0070265=PMID:11101870, GO:0043065=PMID:20935634, GO:0032760=PMID:16127453, GO:0006919=Reactome:REACT_1503, GO:0006915=Reactome:REACT_578, GO:0005123=PMID:7538907, GO:0097191=PMID:18309324, GO:0002224=Reactome:REACT_6966, GO:0097190=PMID:11101870, GO:0045862=PMID:18387192, GO:0044297=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0019048=GO_REF:0000037, GO:0060340=PMID:21109225, GO:0035666=Reactome:REACT_25281, GO:0045121=GO_REF:0000019, GO:0071260=PMID:19593445} Q13158 Protein FADD protein 20110310 {GO:0005515=IPI, GO:0008625=TAS, GO:0043005=IEA, GO:0034142=TAS, GO:0031265=IDA, GO:0031264=IDA, GO:0032813=IPI, GO:0097202=IDA, GO:0002020=IPI, GO:0051291=IEA, GO:0032757=IDA, GO:0042802=IPI, GO:0005829=TAS, GO:0002756=TAS, GO:0051607=IMP, GO:0045944=IDA, GO:0043123=IEP, GO:0034138=TAS, GO:0005164=IEA, GO:0070265=IMP, GO:0043065=IMP, GO:0032760=IDA, GO:0006919=TAS, GO:0006915=TAS, GO:0005123=TAS, GO:0097191=TAS, GO:0002224=TAS, GO:0097190=IDA, GO:0045862=IDA, GO:0044297=IEA, GO:0045087=TAS, GO:0019048=IEA, GO:0060340=IMP, GO:0035666=TAS, GO:0045121=IEA, GO:0071260=IEP} MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, activation of cysteine-type endopeptidase activity, activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, apoptotic signaling pathway, cellular response to mechanical stimulus, defense response to virus, extrinsic apoptotic signaling pathway, extrinsic apoptotic signaling pathway via death domain receptors, innate immune response, necrotic cell death, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of apoptotic process, positive regulation of interleukin-8 production, positive regulation of proteolysis, positive regulation of transcription from RNA polymerase II promoter, positive regulation of tumor necrosis factor production, positive regulation of type I interferon-mediated signaling pathway, protein heterooligomerization, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor signaling pathway, virus-host interaction CD95 death-inducing signaling complex, cell body, cytosol, death-inducing signaling complex, membrane raft, neuron projection death receptor binding, identical protein binding, protease binding, protein binding, tumor necrosis factor receptor binding, tumor necrosis factor receptor superfamily binding Human FADS1 Reactome UniProtKB {GO:0006629=GO_REF:0000002, GO:0019369=GO_REF:0000019, GO:0046456=PMID:10601301, GO:0014070=GO_REF:0000019, GO:0033189=GO_REF:0000019, GO:0007267=PMID:10601301, GO:0005634=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0043231=PMID:10601301, GO:0009744=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0016717=GO_REF:0000019, GO:0009267=PMID:10601301, GO:0032868=GO_REF:0000019, GO:0006636=PMID:10601301, GO:0006355=PMID:10601301, GO:0005506=GO_REF:0000002, GO:0000248=PMID:10601301, GO:0007568=GO_REF:0000019, GO:0006950=GO_REF:0000019, GO:0036109=Reactome:REACT_121147, GO:0008654=PMID:10601301, GO:0043651=Reactome:REACT_121100, GO:0033559=Reactome:REACT_121284, GO:0016020=PMID:10601301, GO:0005789=Reactome:REACT_121259, GO:0016491=PMID:10601301, GO:0045595=PMID:10601301, GO:0016021=PMID:10601301, GO:0022900=GO_REF:0000037, GO:0020037=GO_REF:0000002} O60427 Fatty acid desaturase 1 protein 20130301 {GO:0006629=IEA, GO:0019369=IEA, GO:0046456=TAS, GO:0014070=IEA, GO:0033189=IEA, GO:0007267=NAS, GO:0005634=IEA, GO:0044281=TAS, GO:0043231=NAS, GO:0009744=IEA, GO:0044255=TAS, GO:0016717=IEA, GO:0009267=IDA, GO:0032868=IEA, GO:0006636=IDA, GO:0006355=NAS, GO:0005506=IEA, GO:0000248=TAS, GO:0007568=IEA, GO:0006950=IEA, GO:0036109=TAS, GO:0008654=TAS, GO:0043651=TAS, GO:0033559=TAS, GO:0016020=NAS, GO:0005789=TAS, GO:0016491=IDA, GO:0045595=NAS, GO:0016021=NAS, GO:0022900=IEA, GO:0020037=IEA} aging, alpha-linolenic acid metabolic process, arachidonic acid metabolic process, cell-cell signaling, cellular lipid metabolic process, cellular response to starvation, electron transport chain, icosanoid biosynthetic process, linoleic acid metabolic process, lipid metabolic process, phospholipid biosynthetic process, regulation of cell differentiation, regulation of transcription, DNA-dependent, response to insulin stimulus, response to organic cyclic compound, response to stress, response to sucrose stimulus, response to vitamin A, small molecule metabolic process, unsaturated fatty acid biosynthetic process, unsaturated fatty acid metabolic process endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle, membrane, nucleus C-5 sterol desaturase activity, heme binding, iron ion binding, oxidoreductase activity, oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water Human FADS2 Reactome UniProtKB {GO:0006629=GO_REF:0000002, GO:0006636=GO_REF:0000041, GO:0005506=GO_REF:0000002, GO:0004768=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0036109=Reactome:REACT_121147, GO:0043651=Reactome:REACT_121100, GO:0033559=Reactome:REACT_121284, GO:0016020=PMID:9867867, GO:0005887=PMID:9867867, GO:0005789=Reactome:REACT_121304, GO:0006633=GO_REF:0000002, GO:0022900=GO_REF:0000037, GO:0016717=GO_REF:0000002, GO:0020037=GO_REF:0000002} O95864 Fatty acid desaturase 2 protein 20130301 {GO:0006629=IEA, GO:0006636=IEA, GO:0005506=IEA, GO:0004768=IEA, GO:0044281=TAS, GO:0036109=TAS, GO:0043651=TAS, GO:0033559=TAS, GO:0016020=TAS, GO:0005887=TAS, GO:0005789=TAS, GO:0006633=IEA, GO:0022900=IEA, GO:0016717=IEA, GO:0020037=IEA} alpha-linolenic acid metabolic process, electron transport chain, fatty acid biosynthetic process, linoleic acid metabolic process, lipid metabolic process, small molecule metabolic process, unsaturated fatty acid biosynthetic process, unsaturated fatty acid metabolic process endoplasmic reticulum membrane, integral to plasma membrane, membrane heme binding, iron ion binding, oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water, stearoyl-CoA 9-desaturase activity Human FADS3 UniProtKB UniProtKB {GO:0006629=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0006636=PMID:10860662, GO:0016020=PMID:10860662, GO:0005506=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0006633=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0022900=GO_REF:0000037, GO:0016717=GO_REF:0000002, GO:0020037=GO_REF:0000002} Q9Y5Q0 Fatty acid desaturase 3 protein 20061026 {GO:0006629=IEA, GO:0003674=ND, GO:0006636=NAS, GO:0016020=NAS, GO:0005506=IEA, GO:0005789=IEA, GO:0006633=IEA, GO:0016021=IEA, GO:0022900=IEA, GO:0016717=IEA, GO:0020037=IEA} electron transport chain, fatty acid biosynthetic process, lipid metabolic process, unsaturated fatty acid biosynthetic process endoplasmic reticulum membrane, integral to membrane, membrane heme binding, iron ion binding, molecular_function, oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water Human FADS6 UniProtKB UniProtKB {GO:0006629=GO_REF:0000002, GO:0016491=GO_REF:0000037, GO:0006633=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q8N9I5 Fatty acid desaturase 6 protein 20130413 {GO:0006629=IEA, GO:0016491=IEA, GO:0006633=IEA, GO:0016021=IEA} fatty acid biosynthetic process, lipid metabolic process integral to membrane oxidoreductase activity Human UniProtKB-KW:KW-0560 FAF1 GOC UniProtKB {GO:0045859=PMID:11713579, GO:0005515=PMID:15688372, GO:0043130=PMID:18775313, GO:0008219=PMID:15743842, GO:0048471=PMID:11713579, GO:0043065=PMID:10462485, GO:0019901=PMID:11713579, GO:0051059=PMID:14600157, GO:0042176=PMID:15743842, GO:0031265=PMID:12702723, GO:0019904=GO_REF:0000019, GO:0007253=PMID:14600157, GO:0006915=GO_REF:0000037, GO:0005634=PMID:15596450, GO:0005635=GO_REF:0000019, GO:0030155=GO_REF:0000019, GO:0005829=PMID:15596450, GO:0019887=PMID:11713579, GO:0031334=PMID:15688372, GO:0031072=PMID:15596450, GO:0043161=PMID:15743842, GO:0034098=PMID:18775313, GO:0031625=PMID:18775313} Q9UNN5 FAS-associated factor 1 protein 20130413 {GO:0045859=NAS, GO:0005515=IPI, GO:0043130=IDA, GO:0008219=IMP, GO:0048471=IDA, GO:0043065=NAS, GO:0019901=IDA, GO:0051059=IPI, GO:0042176=IMP, GO:0031265=NAS, GO:0019904=IEA, GO:0007253=IMP, GO:0006915=IEA, GO:0005634=IDA, GO:0005635=IEA, GO:0030155=IEA, GO:0005829=IDA, GO:0019887=NAS, GO:0031334=IMP, GO:0031072=IDA, GO:0043161=NAS, GO:0034098=IDA, GO:0031625=IDA} apoptotic process, cell death, cytoplasmic sequestering of NF-kappaB, positive regulation of apoptotic process, positive regulation of protein complex assembly, proteasomal ubiquitin-dependent protein catabolic process, regulation of cell adhesion, regulation of protein catabolic process, regulation of protein kinase activity CD95 death-inducing signaling complex, Cdc48p-Npl4p-Ufd1p AAA ATPase complex, cytosol, nuclear envelope, nucleus, perinuclear region of cytoplasm NF-kappaB binding, heat shock protein binding, protein binding, protein domain specific binding, protein kinase binding, protein kinase regulator activity, ubiquitin binding, ubiquitin protein ligase binding Human FAF2 BHF-UCL UniProtKB {GO:0005515=PMID:19818707, GO:0006986=GO_REF:0000037, GO:0043130=PMID:18775313, GO:0034098=PMID:18775313, GO:0031625=PMID:18775313} Q96CS3 FAS-associated factor 2 protein 20110707 {GO:0005515=IPI, GO:0006986=IEA, GO:0043130=IDA, GO:0034098=IDA, GO:0031625=IDA} response to unfolded protein Cdc48p-Npl4p-Ufd1p AAA ATPase complex protein binding, ubiquitin binding, ubiquitin protein ligase binding Human FAH Reactome UniProtKB {GO:0004334=Reactome:REACT_1297, GO:0034641=Reactome:REACT_13, GO:0006559=Reactome:REACT_1786, GO:0009072=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0006572=GO_REF:0000037, GO:0006527=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_1297} P16930 Fumarylacetoacetase protein 20130213 {GO:0004334=EXP, GO:0034641=TAS, GO:0006559=TAS, GO:0009072=IEA, GO:0044281=TAS, GO:0006572=IEA, GO:0006527=IEA, GO:0046872=IEA, GO:0005829=TAS} L-phenylalanine catabolic process, arginine catabolic process, aromatic amino acid family metabolic process, cellular nitrogen compound metabolic process, small molecule metabolic process, tyrosine catabolic process cytosol fumarylacetoacetase activity, metal ion binding Human FAHD1 LIFEdb UniProtKB {GO:0005739=GO_REF:0000054, GO:0047621=GO_REF:0000003, GO:0018773=PMID:21878618, GO:0034545=PMID:21878618, GO:0046872=GO_REF:0000037, GO:0005829=PMID:21878618} Q6P587 Acylpyruvase FAHD1, mitochondrial protein 20100607 {GO:0005739=IDA, GO:0047621=IEA, GO:0018773=IDA, GO:0034545=IDA, GO:0046872=IEA, GO:0005829=IDA} cytosol, mitochondrion acetylpyruvate hydrolase activity, acylpyruvate hydrolase activity, fumarylpyruvate hydrolase activity, metal ion binding Human FAHD2A UniProtKB UniProtKB {GO:0016787=GO_REF:0000037, GO:0003824=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q96GK7 Fumarylacetoacetate hydrolase domain-containing protein 2A protein 20130413 {GO:0016787=IEA, GO:0003824=IEA, GO:0046872=IEA} catalytic activity, hydrolase activity, metal ion binding Human UniProtKB-KW:KW-0479 FAHD2B UniProtKB UniProtKB {GO:0016787=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q6P2I3 Fumarylacetoacetate hydrolase domain-containing protein 2B protein 20130413 {GO:0016787=IEA, GO:0046872=IEA} hydrolase activity, metal ion binding Human UniProtKB-KW:KW-0479 FAIM UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0043066=GO_REF:0000002, GO:0006915=GO_REF:0000037} Q9NVQ4 Fas apoptotic inhibitory molecule 1 protein 20130413 {GO:0005737=IEA, GO:0043066=IEA, GO:0006915=IEA} apoptotic process, negative regulation of apoptotic process cytoplasm Human UniProtKB-SubCell:SL-0086 FAIM2 UniProtKB UniProtKB {GO:0043066=PMID:10535980, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0021549=GO_REF:0000024, GO:0005575=GO_REF:0000015, GO:0043523=PMID:17635665, GO:0021702=GO_REF:0000024, GO:0021680=GO_REF:0000024, GO:0021681=GO_REF:0000024, GO:0045211=GO_REF:0000039, GO:0045121=PMID:17635665, GO:0016021=GO_REF:0000037} Q9BWQ8 Protein lifeguard 2 protein 20120116 {GO:0043066=NAS, GO:0030054=IEA, GO:0005886=IEA, GO:0006915=IEA, GO:0021549=ISS, GO:0005575=ND, GO:0043523=IMP, GO:0021702=ISS, GO:0021680=ISS, GO:0021681=ISS, GO:0045211=IEA, GO:0045121=IDA, GO:0016021=IEA} apoptotic process, cerebellar Purkinje cell differentiation, cerebellar Purkinje cell layer development, cerebellar granular layer development, cerebellum development, negative regulation of apoptotic process, regulation of neuron apoptotic process cell junction, cellular_component, integral to membrane, membrane raft, plasma membrane, postsynaptic membrane Human UniProtKB:Q8K097 FAIM3 PINC UniProtKB {GO:0006968=PMID:9586636, GO:0043066=PMID:9586636, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037} O60667 Fas apoptotic inhibitory molecule 3 protein 20040128 {GO:0006968=TAS, GO:0043066=TAS, GO:0005576=IEA, GO:0016021=IEA} cellular defense response, negative regulation of apoptotic process extracellular region, integral to membrane Human FAM101A null null {} null null null null {} null null null FAM101B MGI UniProtKB {GO:0030036=GO_REF:0000019, GO:0031005=PMID:21709252, GO:0001837=GO_REF:0000019, GO:0015629=GO_REF:0000019} Q8N5W9 Protein FAM101B protein 20120411 {GO:0030036=IEA, GO:0031005=IDA, GO:0001837=IEA, GO:0015629=IEA} actin cytoskeleton organization, epithelial to mesenchymal transition actin cytoskeleton filamin binding Human FAM102A null null {} null null null null {} null null null FAM102B null null {} null null null null {} null null null FAM103A1 UniProtKB UniProtKB {GO:0005515=PMID:22099306, GO:0003723=PMID:22099306, GO:0036031=PMID:22099306, GO:0006370=PMID:22099306, GO:0005634=PMID:22099306, GO:0032259=PMID:22099306, GO:0005845=PMID:22099306} Q9BTL3 RNMT-activating mini protein protein 20111125 {GO:0005515=IPI, GO:0003723=IDA, GO:0036031=IDA, GO:0006370=IDA, GO:0005634=IDA, GO:0032259=IMP, GO:0005845=IDA} 7-methylguanosine mRNA capping, methylation, recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex mRNA cap binding complex, nucleus RNA binding, protein binding Human FAM104B null null {} null null null null {} null null null FAM105A null null {} null null null null {} null null null FAM105B null null {} null null null null {} null null null FAM107A UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0005634=PMID:10564580, GO:0001558=PMID:10564580} O95990 Protein FAM107A protein 20031105 {GO:0003674=ND, GO:0005634=IDA, GO:0001558=IDA} regulation of cell growth nucleus molecular_function Human FAM107B null null {} null null null null {} null null null FAM109A UniProtKB UniProtKB {GO:0005802=PMID:21233288, GO:0005515=PMID:21233288, GO:0005794=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0001881=PMID:21233288, GO:0030136=PMID:21233288, GO:0042147=PMID:21233288, GO:0007032=PMID:21233288, GO:0055037=PMID:21233288, GO:0005769=PMID:21233288, GO:0042803=PMID:21233288} Q8N4B1 Sesquipedalian-1 protein 20110427 {GO:0005802=IDA, GO:0005515=IPI, GO:0005794=IEA, GO:0005543=IEA, GO:0001881=IMP, GO:0030136=IDA, GO:0042147=IMP, GO:0007032=IMP, GO:0055037=IDA, GO:0005769=IDA, GO:0042803=IPI} endosome organization, receptor recycling, retrograde transport, endosome to Golgi Golgi apparatus, clathrin-coated vesicle, early endosome, recycling endosome, trans-Golgi network phospholipid binding, protein binding, protein homodimerization activity Human FAM109B UniProtKB UniProtKB {GO:0005802=PMID:21233288, GO:0005515=PMID:21233288, GO:0005794=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0001881=PMID:21233288, GO:0030136=PMID:21233288, GO:0042147=PMID:21233288, GO:0007032=PMID:21233288, GO:0055037=PMID:21233288, GO:0005769=PMID:21233288, GO:0042803=PMID:21233288} Q6ICB4 Sesquipedalian-2 protein 20110427 {GO:0005802=IDA, GO:0005515=IPI, GO:0005794=IEA, GO:0005543=IEA, GO:0001881=IMP, GO:0030136=IDA, GO:0042147=IMP, GO:0007032=IMP, GO:0055037=IDA, GO:0005769=IDA, GO:0042803=IPI} endosome organization, receptor recycling, retrograde transport, endosome to Golgi Golgi apparatus, clathrin-coated vesicle, early endosome, recycling endosome, trans-Golgi network phospholipid binding, protein binding, protein homodimerization activity Human FAM110A IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0005737=GO_REF:0000039, GO:0000922=GO_REF:0000039, GO:0005815=GO_REF:0000039} Q9BQ89 Protein FAM110A protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0000922=IEA, GO:0005815=IEA} cytoplasm, microtubule organizing center, spindle pole protein binding Human UniProtKB:P16333 FAM110B HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0005815=GO_REF:0000039, GO:0005634=GO_REF:0000052} Q8TC76 Protein FAM110B protein 20080205 {GO:0005739=IDA, GO:0005737=IDA, GO:0005815=IEA, GO:0005634=IDA} cytoplasm, microtubule organizing center, mitochondrion, nucleus Human FAM110C UniProtKB UniProtKB {GO:0051897=PMID:19698782, GO:0000922=GO_REF:0000039, GO:0030335=PMID:19698782, GO:0005815=GO_REF:0000039, GO:0043014=PMID:19698782, GO:0005874=GO_REF:0000037, GO:0060491=PMID:19698782, GO:0005634=GO_REF:0000039, GO:0005938=PMID:19698782} Q1W6H9 Protein FAM110C protein 20130307 {GO:0051897=IMP, GO:0000922=IEA, GO:0030335=IMP, GO:0005815=IEA, GO:0043014=IDA, GO:0005874=IEA, GO:0060491=IMP, GO:0005634=IEA, GO:0005938=IDA} positive regulation of cell migration, positive regulation of protein kinase B signaling cascade, regulation of cell projection assembly cell cortex, microtubule, microtubule organizing center, nucleus, spindle pole alpha-tubulin binding Human FAM111A UniProtKB UniProtKB {GO:0005515=PMID:23093934, GO:0005737=PMID:23093934, GO:0000087=PMID:23093934, GO:0005634=PMID:23093934, GO:0003824=GO_REF:0000002, GO:0045071=PMID:23093934} Q96PZ2 Protein FAM111A protein 20130326 {GO:0005515=IPI, GO:0005737=IDA, GO:0000087=IEP, GO:0005634=IDA, GO:0003824=IEA, GO:0045071=IMP} M phase of mitotic cell cycle, negative regulation of viral genome replication cytoplasm, nucleus catalytic activity, protein binding Human FAM111B InterPro UniProtKB {GO:0003824=GO_REF:0000002} Q6SJ93 Protein FAM111B protein 20130413 {GO:0003824=IEA} catalytic activity Human InterPro:IPR009003 FAM114A1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q8IWE2 Protein NOXP20 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 FAM114A2 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0017076=PMID:10843801, GO:0005575=GO_REF:0000015} Q9NRY5 Protein FAM114A2 protein 20061026 {GO:0008150=ND, GO:0017076=NAS, GO:0005575=ND} biological_process cellular_component purine nucleotide binding Human FAM115A null null {} null null null null {} null null null FAM117B null null {} null null null null {} null null null FAM118B null null {} null null null null {} null null null FAM120A HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000039, GO:0003723=GO_REF:0000037} Q9NZB2 Constitutive coactivator of PPAR-gamma-like protein 1 protein 20101115 {GO:0005737=IDA, GO:0005886=IEA, GO:0003723=IEA} cytoplasm, plasma membrane RNA binding Human FAM120AOS null null {} null null null null {} null null null FAM120B UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96EK7 Constitutive coactivator of peroxisome proliferator-activated receptor gamma protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0030154=IEA, GO:0006351=IEA} cell differentiation, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus Human UniProtKB-SubCell:SL-0191 FAM120C null null {} null null null null {} null null null FAM122A null null {} null null null null {} null null null FAM122B null null {} null null null null {} null null null FAM122C null null {} null null null null {} null null null FAM124A null null {} null null null null {} null null null FAM124B IntAct UniProtKB {GO:0005515=PMID:19447967} Q9H5Z6 Protein FAM124B protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:Q99750 FAM126B LIFEdb UniProtKB {GO:0005622=GO_REF:0000054} Q8IXS8 Protein FAM126B protein 20100607 {GO:0005622=IDA} intracellular Human FAM127A UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0005886=GO_REF:0000039, GO:0005575=GO_REF:0000015} O15255 CAAX box protein 1 protein 20061026 {GO:0008150=ND, GO:0005886=IEA, GO:0005575=ND} biological_process cellular_component, plasma membrane Human FAM127B null null {} null null null null {} null null null FAM127C null null {} null null null null {} null null null FAM129A HPA UniProtKB {GO:0003674=GO_REF:0000015, GO:0034976=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0001934=GO_REF:0000024, GO:0001933=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0045727=GO_REF:0000024} Q9BZQ8 Protein Niban protein 20101115 {GO:0003674=ND, GO:0034976=ISS, GO:0005737=IDA, GO:0005886=IDA, GO:0005730=IDA, GO:0001934=ISS, GO:0001933=ISS, GO:0005634=IDA, GO:0045727=ISS} negative regulation of protein phosphorylation, positive regulation of protein phosphorylation, positive regulation of translation, response to endoplasmic reticulum stress cytoplasm, nucleolus, nucleus, plasma membrane molecular_function Human FAM129B UniProtKB UniProtKB {GO:0043066=PMID:21148485, GO:0005543=GO_REF:0000002, GO:0005912=PMID:21148485, GO:0005634=PMID:21148485, GO:0005829=PMID:21148485} Q96TA1 Niban-like protein 1 protein 20110714 {GO:0043066=IMP, GO:0005543=IEA, GO:0005912=IDA, GO:0005634=IDA, GO:0005829=IDA} negative regulation of apoptotic process adherens junction, cytosol, nucleus phospholipid binding NOT Human FAM131A UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q6UXB0 Protein FAM131A protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 FAM131B null null {} null null null null {} null null null FAM131C null null {} null null null null {} null null null FAM133B null null {} null null null null {} null null null FAM134A UniProtKB UniProtKB {GO:0005783=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q8NC44 Protein FAM134A protein 20130413 {GO:0005783=IEA, GO:0016021=IEA} endoplasmic reticulum, integral to membrane Human UniProtKB-KW:KW-0812 FAM134B UniProtKB UniProtKB {GO:0005801=GO_REF:0000024, GO:0005794=GO_REF:0000039, GO:0005783=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0019233=PMID:19838196} Q9H6L5 Protein FAM134B protein 20091023 {GO:0005801=ISS, GO:0005794=IEA, GO:0005783=IEA, GO:0016021=IEA, GO:0019233=IMP} sensory perception of pain Golgi apparatus, cis-Golgi network, endoplasmic reticulum, integral to membrane Human UniProtKB:Q8VE91 FAM134C UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q86VR2 Protein FAM134C protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 FAM135A null null {} null null null null {} null null null FAM135B null null {} null null null null {} null null null FAM136A LIFEdb UniProtKB {GO:0005739=GO_REF:0000039, GO:0005737=GO_REF:0000054} Q96C01 Protein FAM136A protein 20100607 {GO:0005739=IEA, GO:0005737=IDA} cytoplasm, mitochondrion Human FAM13A InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} Q6P521 Protein FAM13A protein 20130413 {GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0007264=TAS, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular GTPase activator activity Human InterPro:IPR000198|InterPro:IPR008936 FAM13B Reactome UniProtKB {GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} Q9NYF5 Protein FAM13B protein 20130301 {GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0007264=TAS, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular GTPase activator activity Human FAM13C null null {} null null null null {} null null null FAM151A BHF-UCL UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0016020=PMID:12975309, GO:0016021=GO_REF:0000037} Q8WW52 Protein FAM151A protein 20090507 {GO:0003674=ND, GO:0008150=ND, GO:0016020=NAS, GO:0016021=IEA} biological_process integral to membrane, membrane molecular_function Human FAM153A null null {} null null null null {} null null null FAM154A null null {} null null null null {} null null null FAM156A LIFEdb UniProtKB {GO:0005635=GO_REF:0000054, GO:0016021=GO_REF:0000037} Q8NDB6 Protein FAM156A/FAM156B protein 20100607 {GO:0005635=IDA, GO:0016021=IEA} integral to membrane, nuclear envelope Human FAM160A2 UniProtKB UniProtKB {GO:0005515=PMID:18799622, GO:0008333=PMID:18799622, GO:0007032=PMID:18799622, GO:0045022=PMID:18799622, GO:0015031=GO_REF:0000037, GO:0007040=PMID:18799622, GO:0070695=PMID:18799622} Q8N612 FTS and Hook-interacting protein protein 20090603 {GO:0005515=IPI, GO:0008333=IMP, GO:0007032=IMP, GO:0045022=IMP, GO:0015031=IEA, GO:0007040=IMP, GO:0070695=IDA} early endosome to late endosome transport, endosome organization, endosome to lysosome transport, lysosome organization, protein transport FHF complex protein binding Human UniProtKB:Q9H8T0 FAM160B1 null null {} null null null null {} null null null FAM160B2 null null {} null null null null {} null null null FAM161A UniProtKB UniProtKB {GO:0005515=PMID:22940612, GO:0042384=PMID:22940612, GO:0005813=PMID:21399614, GO:0005737=GO_REF:0000037, GO:0032391=PMID:22940612, GO:0007601=GO_REF:0000037, GO:0036064=PMID:22940612, GO:0050896=GO_REF:0000037} Q3B820 Protein FAM161A protein 20121017 {GO:0005515=IPI, GO:0042384=IMP, GO:0005813=IDA, GO:0005737=IEA, GO:0032391=IDA, GO:0007601=IEA, GO:0036064=IDA, GO:0050896=IEA} cilium assembly, response to stimulus, visual perception centrosome, cilium basal body, cytoplasm, photoreceptor connecting cilium protein binding Human UniProtKB:Q86SQ7 FAM161B null null {} null null null null {} null null null FAM162A IntAct UniProtKB {GO:0005515=PMID:15082785, GO:0005739=GO_REF:0000039, GO:0043065=PMID:15082785, GO:0006919=PMID:15082785, GO:0090200=PMID:15082785, GO:0006927=PMID:15082785, GO:0071456=PMID:15082785, GO:0016021=GO_REF:0000037, GO:0051402=GO_REF:0000019} Q96A26 Protein FAM162A protein 20130415 {GO:0005515=IPI, GO:0005739=IEA, GO:0043065=IDA, GO:0006919=IDA, GO:0090200=IDA, GO:0006927=IDA, GO:0071456=IDA, GO:0016021=IEA, GO:0051402=IEA} activation of cysteine-type endopeptidase activity involved in apoptotic process, cellular response to hypoxia, neuron apoptotic process, positive regulation of apoptotic process, positive regulation of release of cytochrome c from mitochondria, transformed cell apoptotic process integral to membrane, mitochondrion protein binding Human UniProtKB:P45880 FAM168A null null {} null null null null {} null null null FAM168B UniProtKB UniProtKB {GO:0030424=GO_REF:0000039, GO:0048471=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037} A1KXE4 Myelin-associated neurite-outgrowth inhibitor protein 20130413 {GO:0030424=IEA, GO:0048471=IEA, GO:0005886=IEA, GO:0016021=IEA} axon, integral to membrane, perinuclear region of cytoplasm, plasma membrane Human UniProtKB-SubCell:SL-0198 FAM169A UniProtKB UniProtKB {GO:0005637=GO_REF:0000039} Q9Y6X4 Soluble lamin-associated protein of 75 kDa protein 20130413 {GO:0005637=IEA} nuclear inner membrane Human UniProtKB-SubCell:SL-0179 FAM171A1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q5VUB5 Protein FAM171A1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 FAM171A2 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} A8MVW0 Protein FAM171A2 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 FAM171B UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0003677=GO_REF:0000002} Q6P995 Protein FAM171B protein 20130413 {GO:0016021=IEA, GO:0003677=IEA} integral to membrane DNA binding Human UniProtKB-KW:KW-0812 FAM172A LIFEdb UniProtKB {GO:0005783=GO_REF:0000054, GO:0005576=GO_REF:0000039} Q8WUF8 Protein FAM172A protein 20100607 {GO:0005783=IDA, GO:0005576=IEA} endoplasmic reticulum, extracellular region Human FAM173A UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9BQD7 Protein FAM173A protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 FAM174A UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8TBP5 Membrane protein FAM174A protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 FAM174B UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q3ZCQ3 Membrane protein FAM174B protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 FAM175A IntAct UniProtKB {GO:0005515=PMID:19615732, GO:0070531=PMID:17525340, GO:0010212=PMID:17643121, GO:0031572=PMID:17643121, GO:0005634=PMID:17643121, GO:0045739=PMID:17643121, GO:0031593=PMID:19261749, GO:0006302=PMID:17643121, GO:0016568=GO_REF:0000037} Q6UWZ7 BRCA1-A complex subunit Abraxas protein 20130415 {GO:0005515=IPI, GO:0070531=IDA, GO:0010212=IMP, GO:0031572=IMP, GO:0005634=IDA, GO:0045739=IMP, GO:0031593=IDA, GO:0006302=IMP, GO:0016568=IEA} G2 DNA damage checkpoint, chromatin modification, double-strand break repair, positive regulation of DNA repair, response to ionizing radiation BRCA1-A complex, nucleus polyubiquitin binding, protein binding Human UniProtKB:Q96RL1 FAM175B UniProtKB UniProtKB {GO:0070552=PMID:19214193, GO:0031593=PMID:19261749} Q15018 BRISC complex subunit Abro1 protein 20090422 {GO:0070552=IDA, GO:0031593=IDA} BRISC complex polyubiquitin binding Human FAM177A1 null null {} null null null null {} null null null FAM178A null null {} null null null null {} null null null FAM178B null null {} null null null null {} null null null FAM179B null null {} null null null null {} null null null FAM184A UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q8NB25 Protein FAM184A protein 20101020 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human FAM184B null null {} null null null null {} null null null FAM188A HPA UniProtKB {GO:0005515=PMID:21499297, GO:0031965=GO_REF:0000052, GO:0005509=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000052} Q9H8M7 Protein FAM188A protein 20110516 {GO:0005515=IPI, GO:0031965=IDA, GO:0005509=IEA, GO:0005730=IDA, GO:0006915=IEA, GO:0005634=IDA} apoptotic process nuclear membrane, nucleolus, nucleus calcium ion binding, protein binding Human FAM189A2 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} Q15884 Protein FAM189A2 protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND, GO:0016021=IEA} biological_process cellular_component, integral to membrane molecular_function Human FAM189B InterPro UniProtKB {GO:0005515=PMID:15064722, GO:0008150=GO_REF:0000015, GO:0050699=PMID:15064722, GO:0016021=GO_REF:0000002} Q96AD8 Protein FAM189B protein 20130413 {GO:0005515=IPI, GO:0008150=ND, GO:0050699=IPI, GO:0016021=IEA} biological_process integral to membrane WW domain binding, protein binding Human InterPro:IPR007237 FAM192A LIFEdb UniProtKB {GO:0005634=GO_REF:0000054} Q9GZU8 Protein FAM192A protein 20100607 {GO:0005634=IDA} nucleus Human FAM193B null null {} null null null null {} null null null FAM195A null null {} null null null null {} null null null FAM195B null null {} null null null null {} null null null FAM199X null null {} null null null null {} null null null FAM19A4 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q96LR4 Protein FAM19A4 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 FAM200A UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0003676=GO_REF:0000002} Q8TCP9 Protein FAM200A protein 20130413 {GO:0016021=IEA, GO:0003676=IEA} integral to membrane nucleic acid binding Human UniProtKB-KW:KW-0812 FAM203A UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q9BTY7 Protein FAM203A protein 20080604 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human FAM206A InterPro UniProtKB {GO:0005960=GO_REF:0000002, GO:0006546=GO_REF:0000002} Q9NX38 Protein FAM206A protein 20130413 {GO:0005960=IEA, GO:0006546=IEA} glycine catabolic process glycine cleavage complex Human InterPro:IPR002930 FAM207A null null {} null null null null {} null null null FAM208A null null {} null null null null {} null null null FAM208B null null {} null null null null {} null null null FAM20B UniProtKB UniProtKB {GO:0005794=PMID:19473117, GO:0000139=GO_REF:0000039, GO:0016301=GO_REF:0000037, GO:0016773=PMID:19473117, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037} O75063 Glycosaminoglycan xylosylkinase protein 20100514 {GO:0005794=IDA, GO:0000139=IEA, GO:0016301=IEA, GO:0016773=IDA, GO:0016021=IEA, GO:0005524=IEA} Golgi apparatus, Golgi membrane, integral to membrane ATP binding, kinase activity, phosphotransferase activity, alcohol group as acceptor Human FAM20C ENSEMBL UniProtKB {GO:0045669=GO_REF:0000019, GO:0001501=GO_REF:0000019, GO:0030501=GO_REF:0000019, GO:0097187=GO_REF:0000019, GO:0040036=GO_REF:0000019, GO:0004674=GO_REF:0000037, GO:0071895=GO_REF:0000019, GO:0070166=GO_REF:0000019, GO:0005509=GO_REF:0000019, GO:0051174=GO_REF:0000019, GO:0036179=GO_REF:0000019, GO:0005615=GO_REF:0000019} Q8IXL6 Extracellular serine/threonine protein kinase FAM20C protein 20130413 {GO:0045669=IEA, GO:0001501=IEA, GO:0030501=IEA, GO:0097187=IEA, GO:0040036=IEA, GO:0004674=IEA, GO:0071895=IEA, GO:0070166=IEA, GO:0005509=IEA, GO:0051174=IEA, GO:0036179=IEA, GO:0005615=IEA} dentinogenesis, enamel mineralization, odontoblast differentiation, osteoclast maturation, positive regulation of bone mineralization, positive regulation of osteoblast differentiation, regulation of fibroblast growth factor receptor signaling pathway, regulation of phosphorus metabolic process, skeletal system development extracellular space calcium ion binding, protein serine/threonine kinase activity Human Ensembl:ENSMUSP00000026972 FAM210A UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q96ND0 Protein FAM210A protein 20130413 {GO:0005739=IEA, GO:0016021=IEA} integral to membrane, mitochondrion Human UniProtKB-SubCell:SL-0173 FAM210B UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q96KR6 Protein FAM210B protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 FAM212A ENSEMBL UniProtKB {GO:0021915=GO_REF:0000019} Q96EL1 Protein FAM212A protein 20130413 {GO:0021915=IEA} neural tube development Human Ensembl:ENSMUSP00000040433 FAM212B null null {} null null null null {} null null null FAM213A UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0005737=PMID:19951071, GO:0016209=PMID:19951071, GO:0045670=PMID:19951071, GO:0055114=PMID:19951071} Q9BRX8 Redox-regulatory protein FAM213A protein 20110918 {GO:0005739=IEA, GO:0005737=IDA, GO:0016209=IDA, GO:0045670=IDA, GO:0055114=IDA} oxidation-reduction process, regulation of osteoclast differentiation cytoplasm, mitochondrion antioxidant activity Human FAM213B Reactome UniProtKB {GO:0019371=Reactome:REACT_150149, GO:0019369=Reactome:REACT_147851, GO:0001516=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0016616=GO_REF:0000024, GO:0005829=GO_REF:0000039} Q8TBF2 Prostamide/prostaglandin F synthase protein 20130301 {GO:0019371=TAS, GO:0019369=TAS, GO:0001516=ISS, GO:0044281=TAS, GO:0016616=ISS, GO:0005829=IEA} arachidonic acid metabolic process, cyclooxygenase pathway, prostaglandin biosynthetic process, small molecule metabolic process cytosol oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Human FAM214A null null {} null null null null {} null null null FAM214B LIFEdb UniProtKB {GO:0005634=GO_REF:0000054} Q7L5A3 Protein FAM214B protein 20100607 {GO:0005634=IDA} nucleus Human FAM21A UniProtKB UniProtKB {GO:0031901=GO_REF:0000039, GO:0071203=GO_REF:0000024, GO:0042147=GO_REF:0000024, GO:0005769=GO_REF:0000024} Q641Q2 WASH complex subunit FAM21A protein 20091127 {GO:0031901=IEA, GO:0071203=ISS, GO:0042147=ISS, GO:0005769=ISS} retrograde transport, endosome to Golgi WASH complex, early endosome, early endosome membrane Human UniProtKB:Q9Y4E1 FAM21B UniProtKB UniProtKB {GO:0031901=GO_REF:0000039, GO:0071203=GO_REF:0000024, GO:0042147=GO_REF:0000024, GO:0005769=GO_REF:0000024} Q5SNT6 WASH complex subunit FAM21B protein 20091127 {GO:0031901=IEA, GO:0071203=ISS, GO:0042147=ISS, GO:0005769=ISS} retrograde transport, endosome to Golgi WASH complex, early endosome, early endosome membrane Human UniProtKB:Q9Y4E1 FAM21C MGI UniProtKB {GO:0005515=PMID:19922874, GO:0005886=GO_REF:0000039, GO:0031901=GO_REF:0000039, GO:0071203=PMID:19922875, GO:0042147=PMID:19922874, GO:0005769=PMID:19922874, GO:0005768=PMID:20923837} Q9Y4E1 WASH complex subunit FAM21C protein 20120912 {GO:0005515=IPI, GO:0005886=IEA, GO:0031901=IEA, GO:0071203=IDA, GO:0042147=IMP, GO:0005769=IDA, GO:0005768=IDA} retrograde transport, endosome to Golgi WASH complex, early endosome, early endosome membrane, endosome, plasma membrane protein binding Human FAM26E UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0006811=GO_REF:0000037} Q8N5C1 Protein FAM26E protein 20130413 {GO:0016021=IEA, GO:0006811=IEA} ion transport integral to membrane Human UniProtKB-KW:KW-0812 FAM27E3 null null {} null null null null {} null null null FAM32A LIFEdb UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0007049=GO_REF:0000037, GO:0005730=GO_REF:0000054, GO:0006915=GO_REF:0000037} Q9Y421 Protein FAM32A protein 20100607 {GO:0008150=ND, GO:0003674=ND, GO:0007049=IEA, GO:0005730=IDA, GO:0006915=IEA} apoptotic process, biological_process, cell cycle nucleolus molecular_function Human FAM35A null null {} null null null null {} null null null FAM3A UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005576=GO_REF:0000039, GO:0005575=GO_REF:0000015} P98173 Protein FAM3A protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0005576=IEA, GO:0005575=ND} biological_process cellular_component, extracellular region molecular_function Human FAM3B UniProtKB UniProtKB {GO:0006915=GO_REF:0000037, GO:0005576=PMID:12160727, GO:0005125=PMID:12160727, GO:0030073=PMID:12160727, GO:0005615=GO_REF:0000037} P58499 Protein FAM3B protein 20021105 {GO:0006915=IEA, GO:0005576=NAS, GO:0005125=NAS, GO:0030073=IDA, GO:0005615=IEA} apoptotic process, insulin secretion extracellular region, extracellular space cytokine activity Human FAM3C HPA UniProtKB {GO:0008150=GO_REF:0000015, GO:0005794=GO_REF:0000052, GO:0016023=GO_REF:0000039, GO:0005576=PMID:12160727, GO:0007275=GO_REF:0000037, GO:0005125=PMID:12160727} Q92520 Protein FAM3C protein 20120912 {GO:0008150=ND, GO:0005794=IDA, GO:0016023=IEA, GO:0005576=NAS, GO:0007275=IEA, GO:0005125=NAS} biological_process, multicellular organismal development Golgi apparatus, cytoplasmic membrane-bounded vesicle, extracellular region cytokine activity Human FAM43B null null {} null null null null {} null null null FAM45A null null {} null null null null {} null null null FAM46A null null {} null null null null {} null null null FAM46B null null {} null null null null {} null null null FAM46C null null {} null null null null {} null null null FAM46D null null {} null null null null {} null null null FAM47B null null {} null null null null {} null null null FAM49B ENSEMBL UniProtKB {GO:0005929=GO_REF:0000019} Q9NW21 Protein FAM49B protein 20130413 {GO:0005929=IEA} cilium Human Ensembl:ENSMUSP00000066359 FAM50A LIFEdb UniProtKB {GO:0003674=GO_REF:0000015, GO:0005634=GO_REF:0000054, GO:0007283=PMID:10534398} Q14320 Protein FAM50A protein 20100607 {GO:0003674=ND, GO:0005634=IDA, GO:0007283=NAS} spermatogenesis nucleus molecular_function Human FAM50B InterPro UniProtKB {GO:0005634=GO_REF:0000002} Q9Y247 Protein FAM50B protein 20130413 {GO:0005634=IEA} nucleus Human InterPro:IPR007005 FAM53A UniProtKB UniProtKB {GO:0005634=GO_REF:0000039} Q6NSI3 Protein FAM53A protein 20130413 {GO:0005634=IEA} nucleus Human UniProtKB-SubCell:SL-0191 FAM53B UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q14153 Protein FAM53B protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human FAM53C null null {} null null null null {} null null null FAM57A UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q8TBR7 Protein FAM57A protein 20130413 {GO:0005886=IEA, GO:0016021=IEA} integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 FAM58A UniProtKB UniProtKB {GO:0005515=PMID:18297069, GO:0006355=GO_REF:0000002, GO:0019901=GO_REF:0000002, GO:0000079=GO_REF:0000002} Q8N1B3 Cyclin-related protein FAM58A protein 20100114 {GO:0005515=IPI, GO:0006355=IEA, GO:0019901=IEA, GO:0000079=IEA} regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of transcription, DNA-dependent protein binding, protein kinase binding Human UniProtKB:Q9NSC2 FAM5B UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q9C0B6 Protein FAM5B protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 FAM5C UniProtKB UniProtKB {GO:0005783=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0045786=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0007399=GO_REF:0000019} Q76B58 Protein FAM5C protein 20130413 {GO:0005783=IEA, GO:0043025=IEA, GO:0005576=IEA, GO:0045786=IEA, GO:0030425=IEA, GO:0007399=IEA} negative regulation of cell cycle, nervous system development dendrite, endoplasmic reticulum, extracellular region, neuronal cell body Human UniProtKB-SubCell:SL-0243 FAM60A UniProtKB UniProtKB {GO:0030336=PMID:22984288, GO:0016580=PMID:22984288} Q9NP50 Protein FAM60A protein 20121018 {GO:0030336=IMP, GO:0016580=IDA} negative regulation of cell migration Sin3 complex Human FAM63A UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q8N5J2 Protein FAM63A protein 20081126 {GO:0008150=ND, GO:0005575=ND} biological_process cellular_component Human FAM63B UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q8NBR6 Protein FAM63B protein 20081126 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human FAM64A BHF-UCL UniProtKB {GO:0005515=PMID:16491119, GO:0005730=PMID:16491119} Q9BSJ6 Protein FAM64A protein 20100118 {GO:0005515=IPI, GO:0005730=IDA} nucleolus protein binding Human FAM65A UniProtKB UniProtKB {GO:0005737=GO_REF:0000024} Q6ZS17 Protein FAM65A protein 20110316 {GO:0005737=ISS} cytoplasm Human UniProtKB:Q68FE6 FAM65B UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0007517=GO_REF:0000037, GO:0030175=GO_REF:0000039, GO:0005856=GO_REF:0000039, GO:0030154=GO_REF:0000037} Q9Y4F9 Protein FAM65B protein 20130413 {GO:0005739=IEA, GO:0007517=IEA, GO:0030175=IEA, GO:0005856=IEA, GO:0030154=IEA} cell differentiation, muscle organ development cytoskeleton, filopodium, mitochondrion Human UniProtKB-SubCell:SL-0286 FAM69B UniProtKB UniProtKB {GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q5VUD6 Protein FAM69B protein 20130413 {GO:0005789=IEA, GO:0016021=IEA} endoplasmic reticulum membrane, integral to membrane Human UniProtKB-SubCell:SL-0097 FAM71C null null {} null null null null {} null null null FAM71E2 null null {} null null null null {} null null null FAM72A UniProtKB UniProtKB {GO:0005739=GO_REF:0000039} Q5TYM5 Protein FAM72A protein 20130413 {GO:0005739=IEA} mitochondrion Human UniProtKB-SubCell:SL-0173 FAM72B null null {} null null null null {} null null null FAM72D null null {} null null null null {} null null null FAM73A UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8NAN2 Protein FAM73A protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 FAM76A null null {} null null null null {} null null null FAM76B UniProtKB UniProtKB {GO:0016607=GO_REF:0000039} Q5HYJ3 Protein FAM76B protein 20130413 {GO:0016607=IEA} nuclear speck Human UniProtKB-SubCell:SL-0186 FAM78A null null {} null null null null {} null null null FAM81A null null {} null null null null {} null null null FAM83B null null {} null null null null {} null null null FAM83C null null {} null null null null {} null null null FAM83D UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0000922=GO_REF:0000039, GO:0007067=GO_REF:0000037, GO:0051301=GO_REF:0000037} Q9H4H8 Protein FAM83D protein 20130413 {GO:0005737=IEA, GO:0000922=IEA, GO:0007067=IEA, GO:0051301=IEA} cell division, mitosis cytoplasm, spindle pole Human UniProtKB-SubCell:SL-0086 FAM83F null null {} null null null null {} null null null FAM83G null null {} null null null null {} null null null FAM83H UniProtKB UniProtKB {GO:0031214=GO_REF:0000037} Q6ZRV2 Protein FAM83H protein 20130413 {GO:0031214=IEA} biomineral tissue development Human UniProtKB-KW:KW-0091 FAM84B HGNC UniProtKB {GO:0005515=PMID:12477722, GO:0005737=PMID:12477722, GO:0005886=PMID:12477722} Q96KN1 Protein FAM84B protein 20050729 {GO:0005515=IPI, GO:0005737=IDA, GO:0005886=IDA} cytoplasm, plasma membrane protein binding Human FAM86A null null {} null null null null {} null null null FAM86B1 null null {} null null null null {} null null null FAM86B2 null null {} null null null null {} null null null FAM86C1 null null {} null null null null {} null null null FAM8A1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9UBU6 Protein FAM8A1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 FAM90A1 InterPro UniProtKB {GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q86YD7 Protein FAM90A1 protein 20130413 {GO:0008270=IEA, GO:0003676=IEA} nucleic acid binding, zinc ion binding Human InterPro:IPR001878 FAM91A1 null null {} null null null null {} null null null FAM92A1 null null {} null null null null {} null null null FAM96A UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000039, GO:0007059=GO_REF:0000037, GO:0005575=GO_REF:0000015, GO:0046872=GO_REF:0000037} Q9H5X1 MIP18 family protein FAM96A protein 20080829 {GO:0008150=ND, GO:0003674=ND, GO:0005737=IEA, GO:0007059=IEA, GO:0005575=ND, GO:0046872=IEA} biological_process, chromosome segregation cellular_component, cytoplasm metal ion binding, molecular_function Human FAM96B HPA UniProtKB {GO:0005515=PMID:20797633, GO:0005737=GO_REF:0000052, GO:0007059=PMID:20797633, GO:0097361=PMID:22678361, GO:0005730=GO_REF:0000052, GO:0005819=PMID:20797633, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0071817=PMID:20797633} Q9Y3D0 Mitotic spindle-associated MMXD complex subunit MIP18 protein 20111111 {GO:0005515=IPI, GO:0005737=IDA, GO:0007059=IMP, GO:0097361=IDA, GO:0005730=IDA, GO:0005819=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0071817=IDA} chromosome segregation, small molecule metabolic process CIA complex, MMXD complex, cytoplasm, nucleolus, nucleus, spindle protein binding Human FAM98A null null {} null null null null {} null null null FAM98B UniProtKB UniProtKB {GO:0072669=PMID:21311021} Q52LJ0 Protein FAM98B protein 20110222 {GO:0072669=IDA} tRNA-splicing ligase complex Human FAM98C null null {} null null null null {} null null null FAN1 UniProtKB UniProtKB {GO:0005515=PMID:20603016, GO:0043130=PMID:20603016, GO:0000287=PMID:20603016, GO:0008409=PMID:20603073, GO:0004528=GO_REF:0000003, GO:0006281=PMID:20603073, GO:0000724=PMID:20603016, GO:0005634=PMID:20603073, GO:0006289=PMID:20603016, GO:0017108=PMID:20603073, GO:0003677=GO_REF:0000002, GO:0033683=PMID:20603016} Q9Y2M0 Fanconi-associated nuclease 1 protein 20100721 {GO:0005515=IPI, GO:0043130=IDA, GO:0000287=TAS, GO:0008409=IDA, GO:0004528=IEA, GO:0006281=IMP, GO:0000724=IMP, GO:0005634=IDA, GO:0006289=IMP, GO:0017108=IDA, GO:0003677=IEA, GO:0033683=IMP} DNA repair, double-strand break repair via homologous recombination, nucleotide-excision repair, nucleotide-excision repair, DNA incision nucleus 5'-3' exonuclease activity, 5'-flap endonuclease activity, DNA binding, magnesium ion binding, phosphodiesterase I activity, protein binding, ubiquitin binding Human UniProtKB:Q9BXW9 FANCA BHF-UCL UniProtKB {GO:0005515=PMID:11726552, GO:0008585=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0006281=Reactome:REACT_216, GO:0006461=PMID:9398857, GO:0042127=GO_REF:0000019, GO:0005634=PMID:11726552, GO:0005654=Reactome:REACT_18429, GO:0008584=GO_REF:0000019, GO:0043240=PMID:22343915, GO:0007140=GO_REF:0000019} O15360 Fanconi anemia group A protein protein 20110811 {GO:0005515=IPI, GO:0008585=IEA, GO:0005737=IEA, GO:0006281=TAS, GO:0006461=TAS, GO:0042127=IEA, GO:0005634=IDA, GO:0005654=TAS, GO:0008584=IEA, GO:0043240=IDA, GO:0007140=IEA} DNA repair, female gonad development, male gonad development, male meiosis, protein complex assembly, regulation of cell proliferation Fanconi anaemia nuclear complex, cytoplasm, nucleoplasm, nucleus protein binding Human FANCB Reactome UniProtKB {GO:0006281=Reactome:REACT_216, GO:0005654=Reactome:REACT_18429, GO:0043240=PMID:20347428} Q8NB91 Fanconi anemia group B protein protein 20130213 {GO:0006281=TAS, GO:0005654=TAS, GO:0043240=IDA} DNA repair Fanconi anaemia nuclear complex, nucleoplasm Human FANCC Reactome UniProtKB {GO:0005515=PMID:9596688, GO:0005737=PMID:9398857, GO:0006281=Reactome:REACT_216, GO:0006461=PMID:9398857, GO:0019430=GO_REF:0000019, GO:0005654=Reactome:REACT_18429, GO:0005634=PMID:9398857, GO:0006289=GO_REF:0000019, GO:0002262=GO_REF:0000019, GO:0007281=GO_REF:0000019, GO:0043240=PMID:22266823, GO:0005829=PMID:9596688} Q00597 Fanconi anemia group C protein protein 20130213 {GO:0005515=IPI, GO:0005737=TAS, GO:0006281=TAS, GO:0006461=TAS, GO:0019430=IEA, GO:0005654=TAS, GO:0005634=TAS, GO:0006289=IEA, GO:0002262=IEA, GO:0007281=IEA, GO:0043240=IDA, GO:0005829=IDA} DNA repair, germ cell development, myeloid cell homeostasis, nucleotide-excision repair, protein complex assembly, removal of superoxide radicals Fanconi anaemia nuclear complex, cytoplasm, cytosol, nucleoplasm, nucleus protein binding Human FANCD2 IntAct UniProtKB {GO:0005515=PMID:18212739, GO:0007129=GO_REF:0000019, GO:0000793=GO_REF:0000019, GO:0006281=Reactome:REACT_216, GO:0007276=GO_REF:0000019, GO:0005654=Reactome:REACT_18429, GO:0010332=PMID:12874027} Q9BXW9 Fanconi anemia group D2 protein protein 20130415 {GO:0005515=IPI, GO:0007129=IEA, GO:0000793=IEA, GO:0006281=TAS, GO:0007276=IEA, GO:0005654=TAS, GO:0010332=IDA} DNA repair, gamete generation, response to gamma radiation, synapsis condensed chromosome, nucleoplasm protein binding Human UniProtKB:P51587 FANCE Reactome UniProtKB {GO:0003674=GO_REF:0000015, GO:0006281=Reactome:REACT_216, GO:0005654=Reactome:REACT_18429, GO:0005634=PMID:11001585, GO:0043240=PMID:22266823} Q9HB96 Fanconi anemia group E protein protein 20130213 {GO:0003674=ND, GO:0006281=TAS, GO:0005654=TAS, GO:0005634=NAS, GO:0043240=IDA} DNA repair Fanconi anaemia nuclear complex, nucleoplasm, nucleus molecular_function Human FANCF IntAct UniProtKB {GO:0005515=PMID:12649160, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0006281=Reactome:REACT_216, GO:0005654=Reactome:REACT_18429, GO:0043240=PMID:20347428} Q9NPI8 Fanconi anemia group F protein protein 20130415 {GO:0005515=IPI, GO:0003674=ND, GO:0008150=ND, GO:0006281=TAS, GO:0005654=TAS, GO:0043240=IDA} DNA repair, biological_process Fanconi anaemia nuclear complex, nucleoplasm molecular_function, protein binding Human UniProtKB:O15360 FANCG IntAct UniProtKB {GO:0003684=PMID:9806548, GO:0005739=PMID:17060495, GO:0005515=PMID:16189514, GO:0009314=GO_REF:0000019, GO:0001541=GO_REF:0000019, GO:0006281=Reactome:REACT_216, GO:0007286=GO_REF:0000019, GO:0000075=PMID:9256465, GO:0005654=Reactome:REACT_18429, GO:0007005=PMID:17060495, GO:0006974=GO_REF:0000019, GO:0043240=PMID:22343915} O15287 Fanconi anemia group G protein protein 20130415 {GO:0003684=TAS, GO:0005739=IDA, GO:0005515=IPI, GO:0009314=IEA, GO:0001541=IEA, GO:0006281=TAS, GO:0007286=IEA, GO:0000075=TAS, GO:0005654=TAS, GO:0007005=IMP, GO:0006974=IEA, GO:0043240=IDA} DNA repair, cell cycle checkpoint, mitochondrion organization, ovarian follicle development, response to DNA damage stimulus, response to radiation, spermatid development Fanconi anaemia nuclear complex, mitochondrion, nucleoplasm damaged DNA binding, protein binding Human UniProtKB:O15360 FANCI HPA UniProtKB {GO:0005515=PMID:20603015, GO:0007049=GO_REF:0000037, GO:0006281=Reactome:REACT_216, GO:0005886=GO_REF:0000052, GO:0031398=PMID:18029348, GO:0005654=Reactome:REACT_18367, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037} Q9NVI1 Fanconi anemia group I protein protein 20110516 {GO:0005515=IPI, GO:0007049=IEA, GO:0006281=TAS, GO:0005886=IDA, GO:0031398=IDA, GO:0005654=TAS, GO:0005634=IDA, GO:0003677=IEA} DNA repair, cell cycle, positive regulation of protein ubiquitination nucleoplasm, nucleus, plasma membrane DNA binding, protein binding Human FANCL Reactome UniProtKB {GO:0005737=GO_REF:0000039, GO:0004842=Reactome:REACT_18429, GO:0006513=PMID:16916645, GO:0006281=Reactome:REACT_216, GO:0007276=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0005654=Reactome:REACT_18429, GO:0008270=GO_REF:0000002, GO:0005635=GO_REF:0000019, GO:0031625=PMID:19111657, GO:0006974=PMID:16916645, GO:0043240=PMID:22343915} Q9NW38 E3 ubiquitin-protein ligase FANCL protein 20130213 {GO:0005737=IEA, GO:0004842=TAS, GO:0006513=IDA, GO:0006281=TAS, GO:0007276=IEA, GO:0042127=IEA, GO:0005654=TAS, GO:0008270=IEA, GO:0005635=IEA, GO:0031625=IPI, GO:0006974=IMP, GO:0043240=IDA} DNA repair, gamete generation, protein monoubiquitination, regulation of cell proliferation, response to DNA damage stimulus Fanconi anaemia nuclear complex, cytoplasm, nuclear envelope, nucleoplasm ubiquitin protein ligase binding, ubiquitin-protein ligase activity, zinc ion binding Human FANCM Reactome UniProtKB {GO:0008026=GO_REF:0000002, GO:0005515=PMID:20347429, GO:0071821=PMID:20347428, GO:0006259=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0043240=PMID:20347428, GO:0004518=GO_REF:0000002, GO:0006281=Reactome:REACT_216, GO:0003682=PMID:20347429, GO:0000712=PMID:20347428, GO:0031297=PMID:20347428, GO:0005654=Reactome:REACT_18429} Q8IYD8 Fanconi anemia group M protein protein 20130213 {GO:0008026=IEA, GO:0005515=IPI, GO:0071821=IDA, GO:0006259=IEA, GO:0003677=IEA, GO:0005524=IEA, GO:0043240=IDA, GO:0004518=IEA, GO:0006281=TAS, GO:0003682=IDA, GO:0000712=IMP, GO:0031297=IMP, GO:0005654=TAS} DNA metabolic process, DNA repair, replication fork processing, resolution of meiotic recombination intermediates FANCM-MHF complex, Fanconi anaemia nuclear complex, nucleoplasm ATP binding, ATP-dependent helicase activity, DNA binding, chromatin binding, nuclease activity, protein binding Human FANK1 HPA UniProtKB {GO:0005737=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q8TC84 Fibronectin type 3 and ankyrin repeat domains protein 1 protein 20120912 {GO:0005737=IEA, GO:0005730=IDA, GO:0005634=IDA} cytoplasm, nucleolus, nucleus NOT Human FAP BHF-UCL UniProtKB {GO:0005515=PMID:16651416, GO:0030054=GO_REF:0000037, GO:0004252=GO_REF:0000002, GO:0031258=GO_REF:0000039, GO:0051917=PMID:17317851, GO:0002020=PMID:17317851, GO:0005615=PMID:17317851, GO:0010716=PMID:16651416, GO:0030027=PMID:16651416, GO:0042803=PMID:9247085, GO:0004175=PMID:17317851, GO:0016020=GO_REF:0000002, GO:0043542=PMID:16651416, GO:0071438=GO_REF:0000039, GO:0006508=GO_REF:0000037, GO:0046983=PMID:9065413, GO:0008236=PMID:9065413, GO:0008233=PMID:9688278, GO:0016021=PMID:9065413, GO:0008239=PMID:7911242, GO:0004222=PMID:9065413} Q12884 Seprase protein 20110203 {GO:0005515=IPI, GO:0030054=IEA, GO:0004252=IEA, GO:0031258=IEA, GO:0051917=IC, GO:0002020=IPI, GO:0005615=IDA, GO:0010716=IDA, GO:0030027=IDA, GO:0042803=NAS, GO:0004175=IDA, GO:0016020=IEA, GO:0043542=IDA, GO:0071438=IEA, GO:0006508=IEA, GO:0046983=NAS, GO:0008236=IMP, GO:0008233=IDA, GO:0016021=NAS, GO:0008239=NAS, GO:0004222=TAS} endothelial cell migration, negative regulation of extracellular matrix disassembly, proteolysis, regulation of fibrinolysis cell junction, extracellular space, integral to membrane, invadopodium membrane, lamellipodium, lamellipodium membrane, membrane dipeptidyl-peptidase activity, endopeptidase activity, metalloendopeptidase activity, peptidase activity, protease binding, protein binding, protein dimerization activity, protein homodimerization activity, serine-type endopeptidase activity, serine-type peptidase activity contributes_to Human FAR1 Reactome UniProtKB {GO:0005782=Reactome:REACT_17006, GO:0008611=Reactome:REACT_1407, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0035336=PMID:15220348, GO:0080019=PMID:15220348, GO:0044255=Reactome:REACT_16957, GO:0005778=PMID:21525035, GO:0050062=GO_REF:0000019, GO:0046474=PMID:20071337, GO:0010025=GO_REF:0000019, GO:0005777=PMID:20071337} Q8WVX9 Fatty acyl-CoA reductase 1 protein 20130301 {GO:0005782=TAS, GO:0008611=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0035336=IDA, GO:0080019=IDA, GO:0044255=TAS, GO:0005778=IDA, GO:0050062=IEA, GO:0046474=IDA, GO:0010025=IEA, GO:0005777=IDA} cellular lipid metabolic process, ether lipid biosynthetic process, glycerophospholipid biosynthetic process, long-chain fatty-acyl-CoA metabolic process, small molecule metabolic process, wax biosynthetic process integral to membrane, peroxisomal matrix, peroxisomal membrane, peroxisome fatty-acyl-CoA reductase (alcohol-forming) activity, long-chain-fatty-acyl-CoA reductase activity Human FAR2 Reactome UniProtKB {GO:0005782=Reactome:REACT_17042, GO:0008611=Reactome:REACT_1407, GO:0005789=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0035336=PMID:15220348, GO:0080019=PMID:15220348, GO:0044255=Reactome:REACT_16957, GO:0005778=GO_REF:0000039, GO:0050062=GO_REF:0000019, GO:0005777=GO_REF:0000024} Q96K12 Fatty acyl-CoA reductase 2 protein 20130301 {GO:0005782=TAS, GO:0008611=TAS, GO:0005789=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0035336=IDA, GO:0080019=IDA, GO:0044255=TAS, GO:0005778=IEA, GO:0050062=IEA, GO:0005777=ISS} cellular lipid metabolic process, ether lipid biosynthetic process, long-chain fatty-acyl-CoA metabolic process, small molecule metabolic process endoplasmic reticulum membrane, integral to membrane, peroxisomal matrix, peroxisomal membrane, peroxisome fatty-acyl-CoA reductase (alcohol-forming) activity, long-chain-fatty-acyl-CoA reductase activity Human FARP1 PINC UniProtKB {GO:0008092=GO_REF:0000002, GO:0035023=GO_REF:0000002, GO:0007416=GO_REF:0000024, GO:0030425=GO_REF:0000024, GO:0031234=GO_REF:0000024, GO:0005829=GO_REF:0000024, GO:0005622=GO_REF:0000002, GO:0048813=GO_REF:0000024, GO:0005737=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0010923=PMID:19389623, GO:0005089=PMID:9425278, GO:0005856=GO_REF:0000002, GO:0030676=GO_REF:0000024, GO:0019898=GO_REF:0000002} Q9Y4F1 FERM, RhoGEF and pleckstrin domain-containing protein 1 protein 20030904 {GO:0008092=IEA, GO:0035023=IEA, GO:0007416=ISS, GO:0030425=ISS, GO:0031234=ISS, GO:0005829=ISS, GO:0005622=IEA, GO:0048813=ISS, GO:0005737=IEA, GO:0005543=IEA, GO:0010923=IDA, GO:0005089=TAS, GO:0005856=IEA, GO:0030676=ISS, GO:0019898=IEA} dendrite morphogenesis, negative regulation of phosphatase activity, regulation of Rho protein signal transduction, synapse assembly cytoplasm, cytoskeleton, cytosol, dendrite, extrinsic to internal side of plasma membrane, extrinsic to membrane, intracellular Rac guanyl-nucleotide exchange factor activity, Rho guanyl-nucleotide exchange factor activity, cytoskeletal protein binding, phospholipid binding Human FARP2 Reactome UniProtKB {GO:0008092=GO_REF:0000002, GO:0071800=GO_REF:0000024, GO:0031532=GO_REF:0000024, GO:0035023=GO_REF:0000002, GO:0030316=GO_REF:0000024, GO:0033623=GO_REF:0000024, GO:0005829=Reactome:REACT_19403, GO:0016322=PMID:12351724, GO:0005622=GO_REF:0000002, GO:0016601=PMID:12351724, GO:0005737=PMID:12351724, GO:0005543=GO_REF:0000002, GO:0007411=Reactome:REACT_18266, GO:0071526=GO_REF:0000024, GO:0005089=PMID:12351724, GO:0007155=GO_REF:0000024, GO:0005856=GO_REF:0000002, GO:0030676=GO_REF:0000024, GO:0019898=GO_REF:0000002} O94887 FERM, RhoGEF and pleckstrin domain-containing protein 2 protein 20090515 {GO:0008092=IEA, GO:0071800=ISS, GO:0031532=ISS, GO:0035023=IEA, GO:0030316=ISS, GO:0033623=ISS, GO:0005829=TAS, GO:0016322=IDA, GO:0005622=IEA, GO:0016601=IDA, GO:0005737=IDA, GO:0005543=IEA, GO:0007411=TAS, GO:0071526=ISS, GO:0005089=IDA, GO:0007155=ISS, GO:0005856=IEA, GO:0030676=ISS, GO:0019898=IEA} Rac protein signal transduction, actin cytoskeleton reorganization, axon guidance, cell adhesion, neuron remodeling, osteoclast differentiation, podosome assembly, regulation of Rho protein signal transduction, regulation of integrin activation, semaphorin-plexin signaling pathway cytoplasm, cytoskeleton, cytosol, extrinsic to membrane, intracellular Rac guanyl-nucleotide exchange factor activity, Rho guanyl-nucleotide exchange factor activity, cytoskeletal protein binding, phospholipid binding Human FARS2 InterPro UniProtKB {GO:0010467=Reactome:REACT_71, GO:0005737=GO_REF:0000002, GO:0000049=GO_REF:0000002, GO:0000287=GO_REF:0000002, GO:0006432=PMID:10329163, GO:0005759=Reactome:REACT_15462, GO:0004826=PMID:10329163, GO:0043039=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0004812=GO_REF:0000002, GO:0008033=PMID:10329163, GO:0006418=Reactome:REACT_15482} Q5JRF7 Phenylalanine--tRNA ligase, mitochondrial protein 20130413 {GO:0010467=TAS, GO:0005737=IEA, GO:0000049=IEA, GO:0000287=IEA, GO:0006432=IDA, GO:0005759=TAS, GO:0004826=IDA, GO:0043039=IEA, GO:0005524=IEA, GO:0004812=IEA, GO:0008033=IDA, GO:0006418=TAS} gene expression, phenylalanyl-tRNA aminoacylation, tRNA aminoacylation, tRNA aminoacylation for protein translation, tRNA processing cytoplasm, mitochondrial matrix ATP binding, aminoacyl-tRNA ligase activity, magnesium ion binding, phenylalanine-tRNA ligase activity, tRNA binding Human InterPro:IPR002319 FARSA HPA UniProtKB {GO:0005515=PMID:21163940, GO:0010467=Reactome:REACT_71, GO:0005737=GO_REF:0000052, GO:0000049=GO_REF:0000002, GO:0006432=GO_REF:0000002, GO:0004826=GO_REF:0000003, GO:0043039=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0004812=GO_REF:0000002, GO:0006418=Reactome:REACT_15482, GO:0005829=Reactome:REACT_15328} Q9Y285 Phenylalanine--tRNA ligase alpha subunit protein 20080818 {GO:0005515=IPI, GO:0010467=TAS, GO:0005737=IDA, GO:0000049=IEA, GO:0006432=IEA, GO:0004826=IEA, GO:0043039=IEA, GO:0005524=IEA, GO:0004812=IEA, GO:0006418=TAS, GO:0005829=TAS} gene expression, phenylalanyl-tRNA aminoacylation, tRNA aminoacylation, tRNA aminoacylation for protein translation cytoplasm, cytosol ATP binding, aminoacyl-tRNA ligase activity, phenylalanine-tRNA ligase activity, protein binding, tRNA binding Human FARSB Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0005737=PMID:10049785, GO:0000287=GO_REF:0000002, GO:0006432=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0004826=GO_REF:0000003, GO:0006412=PMID:10049785, GO:0005524=GO_REF:0000037, GO:0006418=Reactome:REACT_15482, GO:0005829=Reactome:REACT_15328} Q9NSD9 Phenylalanine--tRNA ligase beta subunit protein 20130213 {GO:0010467=TAS, GO:0005737=TAS, GO:0000287=IEA, GO:0006432=IEA, GO:0003723=IEA, GO:0004826=IEA, GO:0006412=TAS, GO:0005524=IEA, GO:0006418=TAS, GO:0005829=TAS} gene expression, phenylalanyl-tRNA aminoacylation, tRNA aminoacylation for protein translation, translation cytoplasm, cytosol ATP binding, RNA binding, magnesium ion binding, phenylalanine-tRNA ligase activity Human FAS HPA UniProtKB {GO:0005515=PMID:21803845, GO:0019724=GO_REF:0000019, GO:0010467=GO_REF:0000019, GO:0031265=PMID:20935634, GO:0031264=PMID:11101870, GO:0051402=GO_REF:0000019, GO:0048536=GO_REF:0000019, GO:0042802=PMID:21382479, GO:0045619=GO_REF:0000019, GO:0051260=GO_REF:0000019, GO:0010940=PMID:16507998, GO:0032464=GO_REF:0000019, GO:0071285=GO_REF:0000019, GO:0009636=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0045121=PMID:21382479, GO:0002377=GO_REF:0000019, GO:0009897=GO_REF:0000019, GO:0004888=GO_REF:0000002, GO:0008625=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0006927=GO_REF:0000019, GO:0006925=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0006924=GO_REF:0000019, GO:0005829=PMID:7533181, GO:0006955=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0045637=GO_REF:0000019, GO:0004872=PMID:7533181, GO:0004871=PMID:9360929, GO:0019900=PMID:7538908, GO:0043066=GO_REF:0000019, GO:0043065=PMID:20935634, GO:0050869=GO_REF:0000019, GO:0006919=Reactome:REACT_1503, GO:0071455=PMID:21382479, GO:0006915=Reactome:REACT_578, GO:0005576=GO_REF:0000039, GO:0042981=PMID:7533181, GO:0006917=PMID:1375228, GO:0097190=Reactome:REACT_1619, GO:0003014=GO_REF:0000019, GO:0007165=PMID:9360929, GO:0006461=PMID:10875918, GO:0016020=GO_REF:0000002, GO:0045060=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0071260=PMID:19593445} P25445 Tumor necrosis factor receptor superfamily member 6 protein 20111111 {GO:0005515=IPI, GO:0019724=IEA, GO:0010467=IEA, GO:0031265=IDA, GO:0031264=IDA, GO:0051402=IEA, GO:0048536=IEA, GO:0042802=IPI, GO:0045619=IEA, GO:0051260=IEA, GO:0010940=IMP, GO:0032464=IEA, GO:0071285=IEA, GO:0009636=IEA, GO:0051384=IEA, GO:0045121=IDA, GO:0002377=IEA, GO:0009897=IEA, GO:0004888=IEA, GO:0008625=IEA, GO:0005886=IDA, GO:0006927=IEA, GO:0006925=IEA, GO:0005634=IDA, GO:0006924=IEA, GO:0005829=NAS, GO:0006955=IEA, GO:0005737=IDA, GO:0045637=IEA, GO:0004872=NAS, GO:0004871=TAS, GO:0019900=IPI, GO:0043066=IEA, GO:0043065=IMP, GO:0050869=IEA, GO:0006919=TAS, GO:0071455=IMP, GO:0006915=TAS, GO:0005576=IEA, GO:0042981=NAS, GO:0006917=TAS, GO:0097190=TAS, GO:0003014=IEA, GO:0007165=TAS, GO:0006461=TAS, GO:0016020=IEA, GO:0045060=IEA, GO:0016021=IEA, GO:0071260=IEP} B cell mediated immunity, activation of cysteine-type endopeptidase activity involved in apoptotic process, activation-induced cell death of T cells, apoptotic process, apoptotic signaling pathway, cellular response to hyperoxia, cellular response to lithium ion, cellular response to mechanical stimulus, extrinsic apoptotic signaling pathway via death domain receptors, gene expression, immune response, immunoglobulin production, induction of apoptosis, inflammatory cell apoptotic process, negative regulation of B cell activation, negative regulation of apoptotic process, negative thymic T cell selection, neuron apoptotic process, positive regulation of apoptotic process, positive regulation of necrotic cell death, positive regulation of protein homooligomerization, protein complex assembly, protein homooligomerization, regulation of apoptotic process, regulation of lymphocyte differentiation, regulation of myeloid cell differentiation, renal system process, response to glucocorticoid stimulus, response to toxic substance, signal transduction, spleen development, transformed cell apoptotic process CD95 death-inducing signaling complex, cytoplasm, cytosol, death-inducing signaling complex, external side of plasma membrane, extracellular region, integral to membrane, membrane, membrane raft, nucleus, plasma membrane identical protein binding, kinase binding, protein binding, receptor activity, signal transducer activity, transmembrane signaling receptor activity Human FASLG BHF-UCL UniProtKB {GO:0005515=PMID:21803845, GO:0008625=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0060554=PMID:11101870, GO:0060555=PMID:11101870, GO:0007267=PMID:7826947, GO:0006925=GO_REF:0000019, GO:0005634=PMID:17557115, GO:0060205=GO_REF:0000039, GO:0005615=PMID:18835034, GO:0006955=GO_REF:0000002, GO:0043525=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0043123=PMID:12761501, GO:0043202=GO_REF:0000039, GO:0005164=GO_REF:0000019, GO:0070265=PMID:11101870, GO:0043065=PMID:14749367, GO:0045742=GO_REF:0000019, GO:0006919=PMID:18293083, GO:0005102=PMID:7826947, GO:0006915=Reactome:REACT_578, GO:0005576=Reactome:REACT_2191, GO:0033554=GO_REF:0000019, GO:0000122=PMID:17557115, GO:0070848=GO_REF:0000019, GO:0097190=PMID:11101870, GO:0005125=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0007165=PMID:7826947, GO:0030644=GO_REF:0000019, GO:0048388=GO_REF:0000019, GO:0005887=PMID:7826947, GO:0005901=GO_REF:0000019, GO:0016525=PMID:18835034, GO:0046666=GO_REF:0000019, GO:0009897=GO_REF:0000019} P48023 Tumor necrosis factor ligand superfamily member 6 protein 20100331 {GO:0005515=IPI, GO:0008625=IEA, GO:0008284=IEA, GO:0048471=IEA, GO:0060554=IDA, GO:0060555=IDA, GO:0007267=TAS, GO:0006925=IEA, GO:0005634=IDA, GO:0060205=IEA, GO:0005615=IDA, GO:0006955=IEA, GO:0043525=IEA, GO:0032496=IEA, GO:0043123=IEP, GO:0043202=IEA, GO:0005164=IEA, GO:0070265=IDA, GO:0043065=IDA, GO:0045742=IEA, GO:0006919=IMP, GO:0005102=TAS, GO:0006915=TAS, GO:0005576=TAS, GO:0033554=IEA, GO:0000122=IDA, GO:0070848=IEA, GO:0097190=IDA, GO:0005125=IEA, GO:0006351=IEA, GO:0007165=TAS, GO:0030644=IEA, GO:0048388=IEA, GO:0005887=TAS, GO:0005901=IEA, GO:0016525=IDA, GO:0046666=IEA, GO:0009897=IEA} activation of cysteine-type endopeptidase activity involved in apoptotic process, activation of necroptosis by extracellular signals, activation of necroptosis of activated-T cells, apoptotic process, apoptotic signaling pathway, cell-cell signaling, cellular chloride ion homeostasis, cellular response to stress, endosomal lumen acidification, extrinsic apoptotic signaling pathway via death domain receptors, immune response, inflammatory cell apoptotic process, necrotic cell death, negative regulation of angiogenesis, negative regulation of transcription from RNA polymerase II promoter, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of apoptotic process, positive regulation of cell proliferation, positive regulation of epidermal growth factor receptor signaling pathway, positive regulation of neuron apoptotic process, response to growth factor stimulus, response to lipopolysaccharide, retinal cell programmed cell death, signal transduction, transcription, DNA-dependent caveola, cytoplasmic membrane-bounded vesicle lumen, external side of plasma membrane, extracellular region, extracellular space, integral to plasma membrane, lysosomal lumen, nucleus, perinuclear region of cytoplasm cytokine activity, protein binding, receptor binding, tumor necrosis factor receptor binding Human FASN HPA UniProtKB {GO:0005515=PMID:18022563, GO:0005886=GO_REF:0000052, GO:0015939=Reactome:REACT_11172, GO:0006767=Reactome:REACT_11238, GO:0044281=Reactome:REACT_111217, GO:0035338=Reactome:REACT_1319, GO:0070402=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0005829=Reactome:REACT_115784, GO:0005739=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0008144=GO_REF:0000019, GO:0019432=Reactome:REACT_1190, GO:0006631=PMID:7835891, GO:0006633=GO_REF:0000019, GO:0004313=GO_REF:0000003, GO:0004312=Reactome:REACT_1497, GO:0044255=Reactome:REACT_22279, GO:0042470=GO_REF:0000039, GO:0005794=GO_REF:0000052, GO:0016295=GO_REF:0000003, GO:0004319=GO_REF:0000003, GO:0016296=GO_REF:0000003, GO:0004315=GO_REF:0000003, GO:0047451=GO_REF:0000003, GO:0004314=GO_REF:0000003, GO:0006084=GO_REF:0000019, GO:0004317=GO_REF:0000002, GO:0004316=GO_REF:0000003, GO:0042587=GO_REF:0000019, GO:0031325=Reactome:REACT_2122, GO:0006112=Reactome:REACT_1505, GO:0006766=Reactome:REACT_11193, GO:0004320=GO_REF:0000003, GO:0008270=GO_REF:0000002} P49327 Fatty acid synthase protein 20101115 {GO:0005515=IPI, GO:0005886=IDA, GO:0015939=TAS, GO:0006767=TAS, GO:0044281=TAS, GO:0035338=TAS, GO:0070402=IEA, GO:0042803=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0005737=IDA, GO:0008144=IEA, GO:0019432=TAS, GO:0006631=TAS, GO:0006633=IEA, GO:0004313=IEA, GO:0004312=TAS, GO:0044255=TAS, GO:0042470=IEA, GO:0005794=IDA, GO:0016295=IEA, GO:0004319=IEA, GO:0016296=IEA, GO:0004315=IEA, GO:0047451=IEA, GO:0004314=IEA, GO:0006084=IEA, GO:0004317=IEA, GO:0004316=IEA, GO:0042587=IEA, GO:0031325=TAS, GO:0006112=TAS, GO:0006766=TAS, GO:0004320=IEA, GO:0008270=IEA} acetyl-CoA metabolic process, cellular lipid metabolic process, energy reserve metabolic process, fatty acid biosynthetic process, fatty acid metabolic process, long-chain fatty-acyl-CoA biosynthetic process, pantothenate metabolic process, positive regulation of cellular metabolic process, small molecule metabolic process, triglyceride biosynthetic process, vitamin metabolic process, water-soluble vitamin metabolic process Golgi apparatus, cytoplasm, cytosol, glycogen granule, melanosome, mitochondrion, plasma membrane "3-hydroxyoctanoyl-acyl-carrier-protein"" dehydratase activity, 3-hydroxypalmitoyl-""acyl-carrier-protein"" dehydratase activity, 3-oxoacyl-""acyl-carrier-protein"" reductase (NADPH) activity, 3-oxoacyl-""acyl-carrier-protein"" synthase activity, NADPH binding, ""acyl-carrier-protein"" S-acetyltransferase activity, ""acyl-carrier-protein"" S-malonyltransferase activity, drug binding, enoyl-""acyl-carrier-protein"" reductase (NADPH, B-specific) activity, fatty acid synthase activity, myristoyl-""acyl-carrier-protein"" hydrolase activity, oleoyl-""acyl-carrier-protein"" hydrolase activity, palmitoyl-""acyl-carrier-protein"" hydrolase activity, protein binding, protein homodimerization activity, zinc ion binding""" Human FASTK PINC UniProtKB {GO:0005515=PMID:7544399, GO:0005739=GO_REF:0000019, GO:0004672=GO_REF:0000002, GO:0004674=PMID:7544399, GO:0016301=GO_REF:0000038, GO:0043484=PMID:17592127, GO:0006468=PMID:7544399, GO:0033867=GO_REF:0000003, GO:0097190=PMID:7544399, GO:0005524=GO_REF:0000037} Q14296 Fas-activated serine/threonine kinase protein 20030904 {GO:0005515=IPI, GO:0005739=IEA, GO:0004672=IEA, GO:0004674=IDA, GO:0016301=IEA, GO:0043484=IMP, GO:0006468=IDA, GO:0033867=IEA, GO:0097190=TAS, GO:0005524=IEA} apoptotic signaling pathway, protein phosphorylation, regulation of RNA splicing mitochondrion ATP binding, Fas-activated serine/threonine kinase activity, kinase activity, protein binding, protein kinase activity, protein serine/threonine kinase activity Human FASTKD1 UniProtKB UniProtKB {GO:0005739=PMID:20869947, GO:0045333=PMID:20869947, GO:0004672=GO_REF:0000002} Q53R41 FAST kinase domain-containing protein 1 protein 20101208 {GO:0005739=IDA, GO:0045333=ISS, GO:0004672=IEA} cellular respiration mitochondrion protein kinase activity Human UniProtKB:Q14CZ7 FASTKD2 UniProtKB UniProtKB {GO:0005739=PMID:20869947, GO:0045333=PMID:20869947, GO:0004672=GO_REF:0000002} Q9NYY8 FAST kinase domain-containing protein 2 protein 20101208 {GO:0005739=IDA, GO:0045333=ISS, GO:0004672=IEA} cellular respiration mitochondrion protein kinase activity Human UniProtKB:Q14CZ7 FASTKD3 UniProtKB UniProtKB {GO:0005739=PMID:20869947, GO:0045333=PMID:20869947, GO:0004672=GO_REF:0000002} Q14CZ7 FAST kinase domain-containing protein 3 protein 20101208 {GO:0005739=IDA, GO:0045333=IMP, GO:0004672=IEA} cellular respiration mitochondrion protein kinase activity Human FASTKD5 UniProtKB UniProtKB {GO:0005739=PMID:20869947, GO:0045333=PMID:20869947, GO:0004672=GO_REF:0000002} Q7L8L6 FAST kinase domain-containing protein 5 protein 20101208 {GO:0005739=IDA, GO:0045333=ISS, GO:0004672=IEA} cellular respiration mitochondrion protein kinase activity Human UniProtKB:Q14CZ7 FAT1 PINC UniProtKB {GO:0005515=PMID:19131340, GO:0048471=PMID:15922730, GO:0030054=GO_REF:0000019, GO:0005886=PMID:15922730, GO:0005509=GO_REF:0000002, GO:0007267=PMID:8586420, GO:0005634=PMID:15922730, GO:0030175=GO_REF:0000019, GO:0009653=PMID:8586420, GO:0030027=GO_REF:0000019, GO:0016337=GO_REF:0000024, GO:0007163=GO_REF:0000024, GO:0016477=GO_REF:0000024, GO:0005887=PMID:8586420, GO:0005911=PMID:15148305, GO:0007015=GO_REF:0000024, GO:0016021=GO_REF:0000038, GO:0007155=PMID:8586420, GO:0007156=GO_REF:0000002} Q14517 Protocadherin Fat 1 protein 20031119 {GO:0005515=IPI, GO:0048471=IDA, GO:0030054=IEA, GO:0005886=IDA, GO:0005509=IEA, GO:0007267=TAS, GO:0005634=IDA, GO:0030175=IEA, GO:0009653=TAS, GO:0030027=IEA, GO:0016337=ISS, GO:0007163=ISS, GO:0016477=ISS, GO:0005887=TAS, GO:0005911=IDA, GO:0007015=ISS, GO:0016021=IEA, GO:0007155=TAS, GO:0007156=IEA} actin filament organization, anatomical structure morphogenesis, cell adhesion, cell migration, cell-cell adhesion, cell-cell signaling, establishment or maintenance of cell polarity, homophilic cell adhesion cell junction, cell-cell junction, filopodium, integral to membrane, integral to plasma membrane, lamellipodium, nucleus, perinuclear region of cytoplasm, plasma membrane calcium ion binding, protein binding Human FAT2 UniProtKB UniProtKB {GO:0005913=PMID:17900869, GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000029, GO:0010631=PMID:17900869, GO:0005634=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000024} Q9NYQ8 Protocadherin Fat 2 protein 20110211 {GO:0005913=IDA, GO:0005886=IEA, GO:0005509=NAS, GO:0010631=IMP, GO:0005634=IEA, GO:0016021=IEA, GO:0007156=ISS} epithelial cell migration, homophilic cell adhesion cell-cell adherens junction, integral to membrane, nucleus, plasma membrane calcium ion binding Human UniProtKB:O88277 FAT3 UniProtKB UniProtKB {GO:0005886=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0007275=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000002} Q8TDW7 Protocadherin Fat 3 protein 20130413 {GO:0005886=IEA, GO:0005509=IEA, GO:0007275=IEA, GO:0016021=IEA, GO:0007156=IEA} homophilic cell adhesion, multicellular organismal development integral to membrane, plasma membrane calcium ion binding Human UniProtKB-KW:KW-0812 FAT4 IntAct UniProtKB {GO:0005515=PMID:22153077, GO:0005886=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000002} Q6V0I7 Protocadherin Fat 4 protein 20130415 {GO:0005515=IPI, GO:0005886=IEA, GO:0005509=IEA, GO:0016021=IEA, GO:0007156=IEA} homophilic cell adhesion integral to membrane, plasma membrane calcium ion binding, protein binding Human UniProtKB:Q9H2K2 FATE1 LIFEdb UniProtKB {GO:0005783=GO_REF:0000054, GO:0016021=GO_REF:0000037} Q969F0 Fetal and adult testis-expressed transcript protein protein 20100607 {GO:0005783=IDA, GO:0016021=IEA} endoplasmic reticulum, integral to membrane Human FAU Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:15883184, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0003723=PMID:8395683, GO:0019058=Reactome:REACT_6167, GO:0015935=PMID:15883184, GO:0005575=GO_REF:0000015, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0000184=Reactome:REACT_75886, GO:0022627=PMID:8706699, GO:0016032=Reactome:REACT_6145, GO:0005840=GO_REF:0000002, GO:0044267=Reactome:REACT_17015} P62861 40S ribosomal protein S30 protein 20130213 {GO:0010467=TAS, GO:0003735=IDA, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0003723=TAS, GO:0019058=TAS, GO:0015935=IDA, GO:0005575=ND, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0008150=ND, GO:0003674=ND, GO:0000184=TAS, GO:0022627=IDA, GO:0016032=TAS, GO:0005840=IEA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, biological_process, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cellular_component, cytosol, cytosolic small ribosomal subunit, ribosome, small ribosomal subunit RNA binding, molecular_function, structural constituent of ribosome Human FBF1 UniProtKB UniProtKB {GO:0090162=PMID:18838552, GO:0043297=PMID:18838552, GO:0005515=PMID:18838552, GO:0043296=PMID:18838552, GO:0000922=PMID:21399614, GO:0005814=GO_REF:0000039, GO:0045095=PMID:18838552} Q8TES7 Fas-binding factor 1 protein 20110518 {GO:0090162=IMP, GO:0043297=IMP, GO:0005515=IPI, GO:0043296=IDA, GO:0000922=IDA, GO:0005814=IEA, GO:0045095=IDA} apical junction assembly, establishment of epithelial cell polarity apical junction complex, centriole, keratin filament, spindle pole protein binding Human FBL BHF-UCL UniProtKB {GO:0005515=PMID:10837141, GO:0016074=GO_REF:0000019, GO:0015030=PMID:16687569, GO:0031428=PMID:17636026, GO:0001652=GO_REF:0000019, GO:0006364=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0008168=GO_REF:0000037, GO:0005730=PMID:16687569, GO:0008033=GO_REF:0000002} P22087 rRNA 2'-O-methyltransferase fibrillarin protein 20091118 {GO:0005515=IPI, GO:0016074=IEA, GO:0015030=IDA, GO:0031428=NAS, GO:0001652=IEA, GO:0006364=IEA, GO:0003723=IEA, GO:0008168=IEA, GO:0005730=IDA, GO:0008033=IEA} rRNA processing, snoRNA metabolic process, tRNA processing Cajal body, box C/D snoRNP complex, granular component, nucleolus RNA binding, methyltransferase activity, protein binding Human FBLIM1 HPA UniProtKB {GO:0001725=PMID:18829455, GO:0016337=PMID:19074766, GO:0030054=GO_REF:0000052, GO:0034329=Reactome:REACT_20676, GO:0031005=PMID:19074766, GO:0008360=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0005938=GO_REF:0000039, GO:0005925=GO_REF:0000039, GO:0033623=PMID:19074766, GO:0043231=GO_REF:0000052, GO:0005829=Reactome:REACT_20572} Q8WUP2 Filamin-binding LIM protein 1 protein 20100326 {GO:0001725=IDA, GO:0016337=IMP, GO:0030054=IDA, GO:0034329=TAS, GO:0031005=IDA, GO:0008360=IEA, GO:0008270=IEA, GO:0005938=IEA, GO:0005925=IEA, GO:0033623=IMP, GO:0043231=IDA, GO:0005829=TAS} cell junction assembly, cell-cell adhesion, regulation of cell shape, regulation of integrin activation cell cortex, cell junction, cytosol, focal adhesion, intracellular membrane-bounded organelle, stress fiber filamin binding, zinc ion binding Human FBLN1 Reactome UniProtKB {GO:0016504=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0007566=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0005509=GO_REF:0000002, GO:0005578=PMID:2269669, GO:0005576=Reactome:REACT_150469, GO:0005201=PMID:2269669, GO:0005604=GO_REF:0000019} P23142 Fibulin-1 protein 20130301 {GO:0016504=IEA, GO:0030198=TAS, GO:0007566=IEA, GO:0019048=IEA, GO:0005509=IEA, GO:0005578=TAS, GO:0005576=TAS, GO:0005201=TAS, GO:0005604=IEA} embryo implantation, extracellular matrix organization, virus-host interaction basement membrane, extracellular region, proteinaceous extracellular matrix calcium ion binding, extracellular matrix structural constituent, peptidase activator activity Human FBLN2 BHF-UCL UniProtKB {GO:0031012=PMID:22261194, GO:0030198=Reactome:REACT_118779, GO:0005509=GO_REF:0000002, GO:0010811=GO_REF:0000019, GO:0005578=GO_REF:0000039, GO:0050840=GO_REF:0000019, GO:0005576=Reactome:REACT_150469, GO:0005201=PMID:7806230} P98095 Fibulin-2 protein 20120228 {GO:0031012=ISS, GO:0030198=TAS, GO:0005509=IEA, GO:0010811=IEA, GO:0005578=IEA, GO:0050840=IEA, GO:0005576=TAS, GO:0005201=TAS} extracellular matrix organization, positive regulation of cell-substrate adhesion extracellular matrix, extracellular region, proteinaceous extracellular matrix calcium ion binding, extracellular matrix binding, extracellular matrix structural constituent colocalizes_with Human UniProtKB:F1SPG5 FBLN5 HPA UniProtKB {GO:0005515=PMID:19570982, GO:0005509=GO_REF:0000002, GO:0005578=PMID:10428823, GO:0005576=Reactome:REACT_150335, GO:0071953=GO_REF:0000024, GO:0008022=PMID:15528465, GO:0001558=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:2000121=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0005178=PMID:10428823, GO:0007160=PMID:10428823, GO:0016020=GO_REF:0000002, GO:0030198=Reactome:REACT_118779, GO:0007596=GO_REF:0000002, GO:0034394=GO_REF:0000024, GO:0048251=GO_REF:0000024, GO:0004888=GO_REF:0000002} Q9UBX5 Fibulin-5 protein 20080205 {GO:0005515=IPI, GO:0005509=IEA, GO:0005578=TAS, GO:0005576=TAS, GO:0071953=ISS, GO:0008022=IPI, GO:0001558=IEA, GO:0005615=IEA, GO:2000121=ISS, GO:0005737=IDA, GO:0005178=TAS, GO:0007160=TAS, GO:0016020=IEA, GO:0030198=TAS, GO:0007596=IEA, GO:0034394=ISS, GO:0048251=ISS, GO:0004888=IEA} blood coagulation, cell-matrix adhesion, elastic fiber assembly, extracellular matrix organization, protein localization to cell surface, regulation of cell growth, regulation of removal of superoxide radicals cytoplasm, elastic fiber, extracellular region, extracellular space, membrane, proteinaceous extracellular matrix calcium ion binding, integrin binding, protein C-terminus binding, protein binding, transmembrane signaling receptor activity Human FBN1 BHF-UCL UniProtKB {GO:0005515=PMID:19570982, GO:0035583=GO_REF:0000024, GO:0035582=GO_REF:0000024, GO:0005509=PMID:7691719, GO:0005578=PMID:3536967, GO:0001527=PMID:1860873, GO:0005576=Reactome:REACT_150459, GO:0005615=PMID:3536967, GO:0005604=PMID:3536967, GO:0031012=GO_REF:0000019, GO:0007507=PMID:15781745, GO:0001501=PMID:8188302, GO:0030198=Reactome:REACT_118779, GO:0005201=PMID:3536967} P35555 Fibrillin-1 protein 20101031 {GO:0005515=IPI, GO:0035583=ISS, GO:0035582=ISS, GO:0005509=IDA, GO:0005578=IDA, GO:0001527=IDA, GO:0005576=TAS, GO:0005615=IDA, GO:0005604=IDA, GO:0031012=IEA, GO:0007507=IMP, GO:0001501=IMP, GO:0030198=TAS, GO:0005201=IDA} extracellular matrix organization, heart development, sequestering of BMP in extracellular matrix, sequestering of TGFbeta in extracellular matrix, skeletal system development basement membrane, extracellular matrix, extracellular region, extracellular space, microfibril, proteinaceous extracellular matrix calcium ion binding, extracellular matrix structural constituent, protein binding Human UniProtKB:Q61554 FBN2 BHF-UCL UniProtKB {GO:0045669=GO_REF:0000024, GO:0035583=GO_REF:0000024, GO:0060346=GO_REF:0000024, GO:0030501=GO_REF:0000024, GO:0030198=Reactome:REACT_118779, GO:0005509=GO_REF:0000002, GO:0005578=PMID:8120105, GO:0001527=PMID:20855508, GO:0005576=Reactome:REACT_150459, GO:0030326=GO_REF:0000019, GO:0009653=PMID:7493032, GO:0005201=GO_REF:0000002} P35556 Fibrillin-2 protein 20101031 {GO:0045669=ISS, GO:0035583=ISS, GO:0060346=ISS, GO:0030501=ISS, GO:0030198=TAS, GO:0005509=IEA, GO:0005578=TAS, GO:0001527=TAS, GO:0005576=TAS, GO:0030326=IEA, GO:0009653=TAS, GO:0005201=IEA} anatomical structure morphogenesis, bone trabecula formation, embryonic limb morphogenesis, extracellular matrix organization, positive regulation of bone mineralization, positive regulation of osteoblast differentiation, sequestering of TGFbeta in extracellular matrix extracellular region, microfibril, proteinaceous extracellular matrix calcium ion binding, extracellular matrix structural constituent Human FBN3 UniProtKB UniProtKB {GO:0005509=GO_REF:0000002, GO:0005578=GO_REF:0000039, GO:0005201=GO_REF:0000002} Q75N90 Fibrillin-3 protein 20130413 {GO:0005509=IEA, GO:0005578=IEA, GO:0005201=IEA} proteinaceous extracellular matrix calcium ion binding, extracellular matrix structural constituent Human UniProtKB-SubCell:SL-0111 FBP1 InterPro UniProtKB {GO:0005515=PMID:16275660, GO:0030308=PMID:19881551, GO:0016208=PMID:18650089, GO:0005975=GO_REF:0000002, GO:0071286=PMID:10222032, GO:0006094=Reactome:REACT_1520, GO:0044281=Reactome:REACT_111217, GO:0035690=PMID:18650089, GO:0046872=PMID:8387495, GO:0005829=Reactome:REACT_379, GO:0006111=PMID:7558035, GO:0046580=PMID:19881551, GO:0005737=PMID:20096900, GO:0051289=PMID:18650089, GO:0016311=PMID:18650089, GO:0006006=Reactome:REACT_723, GO:0045820=PMID:19881551, GO:0048029=GO_REF:0000024, GO:0006002=PMID:16442285, GO:0006000=PMID:7558035, GO:0042132=GO_REF:0000002} Q5VZC3 Fructose-1,6-bisphosphatase 1 protein 20130413 {GO:0005515=IPI, GO:0030308=IDA, GO:0016208=IDA, GO:0005975=IEA, GO:0071286=IDA, GO:0006094=TAS, GO:0044281=TAS, GO:0035690=IDA, GO:0046872=IMP, GO:0005829=TAS, GO:0006111=IMP, GO:0046580=IDA, GO:0005737=IDA, GO:0051289=IDA, GO:0016311=IDA, GO:0006006=TAS, GO:0045820=IDA, GO:0048029=ISS, GO:0006002=IDA, GO:0006000=TAS, GO:0042132=IEA} carbohydrate metabolic process, cellular response to drug, cellular response to magnesium ion, dephosphorylation, fructose 6-phosphate metabolic process, fructose metabolic process, gluconeogenesis, glucose metabolic process, negative regulation of Ras protein signal transduction, negative regulation of cell growth, negative regulation of glycolysis, protein homotetramerization, regulation of gluconeogenesis, small molecule metabolic process cytoplasm, cytosol AMP binding, fructose 1,6-bisphosphate 1-phosphatase activity, metal ion binding, monosaccharide binding, protein binding Human InterPro:IPR000146 FBP2 Reactome UniProtKB {GO:0005975=Reactome:REACT_474, GO:0004331=PMID:9678974, GO:0006094=Reactome:REACT_1520, GO:0006006=Reactome:REACT_723, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_379, GO:0006000=PMID:9678974, GO:0042132=GO_REF:0000003} O00757 Fructose-1,6-bisphosphatase isozyme 2 protein 20130213 {GO:0005975=TAS, GO:0004331=TAS, GO:0006094=TAS, GO:0006006=TAS, GO:0044281=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0006000=TAS, GO:0042132=IEA} carbohydrate metabolic process, fructose metabolic process, gluconeogenesis, glucose metabolic process, small molecule metabolic process cytosol fructose 1,6-bisphosphate 1-phosphatase activity, fructose-2,6-bisphosphate 2-phosphatase activity, metal ion binding Human FBRS ENSEMBL UniProtKB {GO:0048146=GO_REF:0000019, GO:0008083=GO_REF:0000019, GO:0005615=GO_REF:0000019} J3KNZ9 Probable fibrosin-1 protein 20130413 {GO:0048146=IEA, GO:0008083=IEA, GO:0005615=IEA} positive regulation of fibroblast proliferation extracellular space growth factor activity Human Ensembl:ENSMUSP00000043682 FBRSL1 null null {} null null null null {} null null null FBXL12 IntAct UniProtKB {GO:0005515=PMID:21163940, GO:0006511=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0000151=GO_REF:0000019} Q9NXK8 F-box/LRR-repeat protein 12 protein 20130415 {GO:0005515=IPI, GO:0006511=IEA, GO:0005737=IEA, GO:0000151=IEA} ubiquitin-dependent protein catabolic process cytoplasm, ubiquitin ligase complex protein binding Human UniProtKB:Q9H0A6 FBXL13 null null {} null null null null {} null null null FBXL14 UniProtKB UniProtKB {GO:0005515=PMID:19955572, GO:0004842=PMID:19955572, GO:0005737=PMID:19955572, GO:0042787=PMID:19955572} Q8N1E6 F-box/LRR-repeat protein 14 protein 20110719 {GO:0005515=IPI, GO:0004842=IDA, GO:0005737=IDA, GO:0042787=IDA} protein ubiquitination involved in ubiquitin-dependent protein catabolic process cytoplasm protein binding, ubiquitin-protein ligase activity Human FBXL15 UniProtKB UniProtKB {GO:0005515=PMID:21572392, GO:0030513=PMID:21572392, GO:0005737=PMID:21572392, GO:0004842=PMID:21572392, GO:0016567=PMID:21572392, GO:0000086=PMID:21572392, GO:0030282=GO_REF:0000024, GO:0009953=GO_REF:0000024, GO:0031146=PMID:21572392, GO:0019005=PMID:21572392} Q9H469 F-box/LRR-repeat protein 15 protein 20110517 {GO:0005515=IPI, GO:0030513=IMP, GO:0005737=IDA, GO:0004842=IDA, GO:0016567=IDA, GO:0000086=IMP, GO:0030282=ISS, GO:0009953=ISS, GO:0031146=IDA, GO:0019005=IDA} G2/M transition of mitotic cell cycle, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, bone mineralization, dorsal/ventral pattern formation, positive regulation of BMP signaling pathway, protein ubiquitination SCF ubiquitin ligase complex, cytoplasm protein binding, ubiquitin-protein ligase activity Human UniProtKB:D4ABB4 FBXL16 null null {} null null null null {} null null null FBXL17 null null {} null null null null {} null null null FBXL18 null null {} null null null null {} null null null FBXL19 InterPro UniProtKB {GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000002} Q6PCT2 F-box/LRR-repeat protein 19 protein 20130413 {GO:0008270=IEA, GO:0003677=IEA} DNA binding, zinc ion binding Human InterPro:IPR001965|InterPro:IPR002857 FBXL2 PINC UniProtKB {GO:0005515=PMID:15893726, GO:0005516=GO_REF:0000037, GO:0006511=GO_REF:0000019, GO:0005737=PMID:10508920, GO:0004842=GO_REF:0000019, GO:0006513=GO_REF:0000019, GO:0016020=PMID:15893726, GO:0019048=GO_REF:0000037, GO:0006508=PMID:10531035, GO:0006464=PMID:10531035} Q9UKC9 F-box/LRR-repeat protein 2 protein 20050308 {GO:0005515=IPI, GO:0005516=IEA, GO:0006511=IEA, GO:0005737=TAS, GO:0004842=IEA, GO:0006513=IEA, GO:0016020=IDA, GO:0019048=IEA, GO:0006508=TAS, GO:0006464=TAS} cellular protein modification process, protein monoubiquitination, proteolysis, ubiquitin-dependent protein catabolic process, virus-host interaction cytoplasm, membrane calmodulin binding, protein binding, ubiquitin-protein ligase activity Human FBXL20 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q96IG2 F-box/LRR-repeat protein 20 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 FBXL21 UniProtKB UniProtKB {GO:0004842=PMID:10531035, GO:0016567=GO_REF:0000024, GO:0000151=PMID:10531035, GO:0005634=GO_REF:0000024, GO:0048511=GO_REF:0000037, GO:0043153=GO_REF:0000024, GO:0019005=GO_REF:0000024, GO:0005829=GO_REF:0000024} Q9UKT6 F-box/LRR-repeat protein 21 protein 20130315 {GO:0004842=NAS, GO:0016567=ISS, GO:0000151=NAS, GO:0005634=ISS, GO:0048511=IEA, GO:0043153=ISS, GO:0019005=ISS, GO:0005829=ISS} entrainment of circadian clock by photoperiod, protein ubiquitination, rhythmic process SCF ubiquitin ligase complex, cytosol, nucleus, ubiquitin ligase complex ubiquitin-protein ligase activity Human UniProtKB:Q8BFZ4 FBXL22 UniPathway UniProtKB {GO:0030018=GO_REF:0000039, GO:0016567=GO_REF:0000041} Q6P050 F-box and leucine-rich protein 22 protein 20130413 {GO:0030018=IEA, GO:0016567=IEA} protein ubiquitination Z disc Human UniPathway:UPA00143 FBXL3 UniProtKB UniProtKB {GO:0005515=PMID:17463251, GO:0004842=PMID:17463251, GO:0016567=GO_REF:0000024, GO:0042752=PMID:17463251, GO:0000151=PMID:10531035, GO:0005634=GO_REF:0000024, GO:0048511=GO_REF:0000037, GO:0031146=PMID:17463251, GO:0043153=GO_REF:0000024, GO:0019005=PMID:17463251, GO:0005829=GO_REF:0000024} Q9UKT7 F-box/LRR-repeat protein 3 protein 20130315 {GO:0005515=IPI, GO:0004842=IDA, GO:0016567=ISS, GO:0042752=IMP, GO:0000151=NAS, GO:0005634=ISS, GO:0048511=IEA, GO:0031146=IDA, GO:0043153=ISS, GO:0019005=IDA, GO:0005829=ISS} SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, entrainment of circadian clock by photoperiod, protein ubiquitination, regulation of circadian rhythm, rhythmic process SCF ubiquitin ligase complex, cytosol, nucleus, ubiquitin ligase complex protein binding, ubiquitin-protein ligase activity Human UniProtKB:Q8C4V4 FBXL4 HPA UniProtKB {GO:0006511=PMID:10531035, GO:0005737=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0000151=PMID:10531035, GO:0005634=GO_REF:0000052} Q9UKA2 F-box/LRR-repeat protein 4 protein 20101115 {GO:0006511=TAS, GO:0005737=IEA, GO:0005730=IDA, GO:0000151=TAS, GO:0005634=IDA} ubiquitin-dependent protein catabolic process cytoplasm, nucleolus, nucleus, ubiquitin ligase complex NOT Human FBXL5 UniProtKB UniProtKB {GO:0005515=PMID:19762597, GO:0048471=PMID:17532294, GO:0004842=PMID:10531035, GO:0016567=PMID:19762597, GO:0005506=PMID:19762596, GO:0000151=PMID:10531035, GO:0031146=PMID:19762596, GO:0055072=PMID:19762596, GO:0019005=PMID:19762597} Q9UKA1 F-box/LRR-repeat protein 5 protein 20091030 {GO:0005515=IPI, GO:0048471=IDA, GO:0004842=NAS, GO:0016567=IDA, GO:0005506=IDA, GO:0000151=NAS, GO:0031146=IDA, GO:0055072=IMP, GO:0019005=IDA} SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, iron ion homeostasis, protein ubiquitination SCF ubiquitin ligase complex, perinuclear region of cytoplasm, ubiquitin ligase complex iron ion binding, protein binding, ubiquitin-protein ligase activity Human UniProtKB:P48200 FBXL6 GOC UniProtKB {GO:0004842=PMID:10531035, GO:0016567=PMID:10531035, GO:0006508=PMID:10531035} Q8N531 F-box/LRR-repeat protein 6 protein 20130413 {GO:0004842=TAS, GO:0016567=TAS, GO:0006508=TAS} protein ubiquitination, proteolysis ubiquitin-protein ligase activity Human FBXL7 UniProtKB UniProtKB {GO:0006511=PMID:10531035, GO:0004842=PMID:10531035, GO:0005737=GO_REF:0000037, GO:0007067=GO_REF:0000024, GO:0005813=GO_REF:0000024, GO:0016567=GO_REF:0000024, GO:0008283=GO_REF:0000024, GO:0000086=GO_REF:0000024, GO:0000151=PMID:10531035, GO:0031146=GO_REF:0000024, GO:0019005=GO_REF:0000024, GO:0051301=GO_REF:0000037} Q9UJT9 F-box/LRR-repeat protein 7 protein 20120430 {GO:0006511=NAS, GO:0004842=NAS, GO:0005737=IEA, GO:0007067=ISS, GO:0005813=ISS, GO:0016567=ISS, GO:0008283=ISS, GO:0000086=ISS, GO:0000151=NAS, GO:0031146=ISS, GO:0019005=ISS, GO:0051301=IEA} G2/M transition of mitotic cell cycle, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, cell division, cell proliferation, mitosis, protein ubiquitination, ubiquitin-dependent protein catabolic process SCF ubiquitin ligase complex, centrosome, cytoplasm, ubiquitin ligase complex ubiquitin-protein ligase activity Human UniProtKB:Q5BJ29 FBXL8 IntAct UniProtKB {GO:0005515=PMID:19159283} Q96CD0 F-box/LRR-repeat protein 8 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:P63208 FBXO10 UniProtKB UniProtKB {GO:0004842=PMID:10531037, GO:0016567=PMID:10531035, GO:0000151=PMID:10531035} Q9UK96 F-box only protein 10 protein 20010817 {GO:0004842=NAS, GO:0016567=NAS, GO:0000151=NAS} protein ubiquitination ubiquitin ligase complex ubiquitin-protein ligase activity Human FBXO11 HPA UniProtKB {GO:0006511=PMID:10531037, GO:0005737=GO_REF:0000052, GO:0004842=PMID:10531035, GO:0016567=PMID:10531035, GO:0007605=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0016274=PMID:16487488, GO:0000151=PMID:10531037, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0035246=PMID:16487488, GO:0006464=PMID:16487488} Q86XK2 F-box only protein 11 protein 20101115 {GO:0006511=NAS, GO:0005737=IDA, GO:0004842=NAS, GO:0016567=NAS, GO:0007605=IEA, GO:0005730=IDA, GO:0016274=IDA, GO:0000151=NAS, GO:0005634=IDA, GO:0008270=IEA, GO:0035246=IDA, GO:0006464=IDA} cellular protein modification process, peptidyl-arginine N-methylation, protein ubiquitination, sensory perception of sound, ubiquitin-dependent protein catabolic process cytoplasm, nucleolus, nucleus, ubiquitin ligase complex protein-arginine N-methyltransferase activity, ubiquitin-protein ligase activity, zinc ion binding Human FBXO15 ENSEMBL UniProtKB {GO:0019005=GO_REF:0000019} Q8NCQ5 F-box only protein 15 protein 20130413 {GO:0019005=IEA} SCF ubiquitin ligase complex Human Ensembl:ENSMUSP00000045925 FBXO16 null null {} null null null null {} null null null FBXO17 UniProtKB UniProtKB {GO:0005515=PMID:18203720, GO:0030163=GO_REF:0000002, GO:0001948=PMID:18203720, GO:0019005=PMID:18203720} Q96EF6 F-box only protein 17 protein 20100625 {GO:0005515=IPI, GO:0030163=IEA, GO:0001948=IDA, GO:0019005=IDA} protein catabolic process SCF ubiquitin ligase complex glycoprotein binding, protein binding Human FBXO18 HPA UniProtKB {GO:0004003=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000037} Q8NFZ0 F-box only protein 18 protein 20080818 {GO:0004003=IEA, GO:0005634=IDA, GO:0005524=IEA, GO:0003677=IEA} nucleus ATP binding, ATP-dependent DNA helicase activity, DNA binding Human FBXO2 PINC UniProtKB {GO:0004842=PMID:10531035, GO:0016567=GO_REF:0000024, GO:0005783=GO_REF:0000037, GO:0030433=GO_REF:0000019, GO:0031146=GO_REF:0000024, GO:0005829=GO_REF:0000024, GO:0001540=GO_REF:0000019, GO:0001948=GO_REF:0000019, GO:0043197=GO_REF:0000019, GO:0031090=GO_REF:0000039, GO:0006508=PMID:10531035, GO:0030246=GO_REF:0000019, GO:0006516=GO_REF:0000024, GO:0031396=GO_REF:0000019, GO:0006464=PMID:10531035, GO:0019005=GO_REF:0000024} Q9UK22 F-box only protein 2 protein 20030904 {GO:0004842=TAS, GO:0016567=ISS, GO:0005783=IEA, GO:0030433=IEA, GO:0031146=ISS, GO:0005829=ISS, GO:0001540=IEA, GO:0001948=IEA, GO:0043197=IEA, GO:0031090=IEA, GO:0006508=TAS, GO:0030246=IEA, GO:0006516=ISS, GO:0031396=IEA, GO:0006464=TAS, GO:0019005=ISS} ER-associated protein catabolic process, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, cellular protein modification process, glycoprotein catabolic process, protein ubiquitination, proteolysis, regulation of protein ubiquitination SCF ubiquitin ligase complex, cytosol, dendritic spine, endoplasmic reticulum, organelle membrane beta-amyloid binding, carbohydrate binding, glycoprotein binding, ubiquitin-protein ligase activity Human FBXO21 GOC UniProtKB {GO:0006511=PMID:10531035, GO:0004842=PMID:10531035, GO:0016567=PMID:10531035, GO:0000151=PMID:10531035, GO:0003677=GO_REF:0000002} O94952 F-box only protein 21 protein 20130413 {GO:0006511=NAS, GO:0004842=NAS, GO:0016567=NAS, GO:0000151=NAS, GO:0003677=IEA} protein ubiquitination, ubiquitin-dependent protein catabolic process ubiquitin ligase complex DNA binding, ubiquitin-protein ligase activity Human FBXO22 PINC UniProtKB {GO:0000209=GO_REF:0000019, GO:0006511=PMID:10531035, GO:0004842=PMID:10531037, GO:0030018=GO_REF:0000039, GO:2000060=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0032436=GO_REF:0000019, GO:0010830=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0006464=PMID:10531035, GO:0009267=GO_REF:0000019, GO:0006913=GO_REF:0000019} Q8NEZ5 F-box only protein 22 protein 20061107 {GO:0000209=IEA, GO:0006511=TAS, GO:0004842=TAS, GO:0030018=IEA, GO:2000060=IEA, GO:0005737=IEA, GO:0032436=IEA, GO:0010830=IEA, GO:0005634=IEA, GO:0006464=TAS, GO:0009267=IEA, GO:0006913=IEA} cellular protein modification process, cellular response to starvation, nucleocytoplasmic transport, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process, protein polyubiquitination, regulation of myotube differentiation, ubiquitin-dependent protein catabolic process Z disc, cytoplasm, nucleus ubiquitin-protein ligase activity Human FBXO24 UniProtKB UniProtKB {GO:0004842=PMID:10531035, GO:0016567=PMID:10531035, GO:0000151=PMID:10531035} O75426 F-box only protein 24 protein 20010814 {GO:0004842=NAS, GO:0016567=NAS, GO:0000151=NAS} protein ubiquitination ubiquitin ligase complex ubiquitin-protein ligase activity Human FBXO25 UniProtKB UniProtKB {GO:0004842=PMID:10531035, GO:0016567=GO_REF:0000024, GO:0000151=PMID:10531035, GO:0003779=GO_REF:0000037, GO:0005634=GO_REF:0000024, GO:0019005=GO_REF:0000024} Q8TCJ0 F-box only protein 25 protein 20100622 {GO:0004842=NAS, GO:0016567=ISS, GO:0000151=NAS, GO:0003779=IEA, GO:0005634=ISS, GO:0019005=ISS} protein ubiquitination SCF ubiquitin ligase complex, nucleus, ubiquitin ligase complex actin binding, ubiquitin-protein ligase activity Human UniProtKB:Q9D2Y6 FBXO27 UniProtKB UniProtKB {GO:0005515=PMID:18203720, GO:0030163=GO_REF:0000002, GO:0001948=PMID:18203720, GO:0019005=PMID:18203720} Q8NI29 F-box only protein 27 protein 20100625 {GO:0005515=IPI, GO:0030163=IEA, GO:0001948=IDA, GO:0019005=IDA} protein catabolic process SCF ubiquitin ligase complex glycoprotein binding, protein binding Human FBXO28 null null {} null null null null {} null null null FBXO3 GOC UniProtKB {GO:0005515=PMID:22190034, GO:0004842=PMID:10531035, GO:0016567=PMID:10531035, GO:0006508=PMID:10531035, GO:0005634=GO_REF:0000039} Q9UK99 F-box only protein 3 protein 20130413 {GO:0005515=IPI, GO:0004842=TAS, GO:0016567=TAS, GO:0006508=TAS, GO:0005634=IEA} protein ubiquitination, proteolysis nucleus protein binding, ubiquitin-protein ligase activity Human FBXO30 InterPro UniProtKB {GO:0004842=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q8TB52 F-box only protein 30 protein 20130413 {GO:0004842=IEA, GO:0008270=IEA} ubiquitin-protein ligase activity, zinc ion binding Human InterPro:IPR001293|InterPro:IPR013323 FBXO31 UniProtKB UniProtKB {GO:0008054=PMID:19412162, GO:0016567=GO_REF:0000041, GO:0030332=PMID:19412162, GO:0031571=PMID:19412162, GO:0031146=PMID:19412162, GO:0006974=PMID:19412162, GO:0019005=PMID:19412162} Q5XUX0 F-box only protein 31 protein 20090511 {GO:0008054=IMP, GO:0016567=IEA, GO:0030332=IPI, GO:0031571=IMP, GO:0031146=IDA, GO:0006974=IDA, GO:0019005=IDA} SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, cyclin catabolic process, mitotic G1 DNA damage checkpoint, protein ubiquitination, response to DNA damage stimulus SCF ubiquitin ligase complex cyclin binding Human FBXO32 UniPathway UniProtKB {GO:0005737=GO_REF:0000039, GO:0016567=GO_REF:0000041, GO:0005634=GO_REF:0000039} Q969P5 F-box only protein 32 protein 20130413 {GO:0005737=IEA, GO:0016567=IEA, GO:0005634=IEA} protein ubiquitination cytoplasm, nucleus Human UniPathway:UPA00143 FBXO33 UniPathway UniProtKB {GO:0016567=GO_REF:0000041} Q7Z6M2 F-box only protein 33 protein 20130413 {GO:0016567=IEA} protein ubiquitination Human UniPathway:UPA00143 FBXO34 null null {} null null null null {} null null null FBXO38 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039} Q6PIJ6 F-box only protein 38 protein 20130413 {GO:0005737=IEA, GO:0005634=IEA} cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 FBXO4 IntAct UniProtKB {GO:0000209=PMID:20181953, GO:0005515=PMID:21242966, GO:0004842=PMID:10531035, GO:0005737=GO_REF:0000039, GO:0016567=PMID:10531035, GO:0000151=PMID:10531035, GO:0031146=PMID:20159592, GO:0019005=PMID:20181953, GO:0042803=PMID:20181953} Q9UKT5 F-box only protein 4 protein 20130415 {GO:0000209=IDA, GO:0005515=IPI, GO:0004842=IDA, GO:0005737=IEA, GO:0016567=IDA, GO:0000151=IDA, GO:0031146=IDA, GO:0019005=IDA, GO:0042803=IPI} SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, protein polyubiquitination, protein ubiquitination SCF ubiquitin ligase complex, cytoplasm, ubiquitin ligase complex protein binding, protein homodimerization activity, ubiquitin-protein ligase activity Human UniProtKB:P62260 FBXO40 HPA UniProtKB {GO:0042692=PMID:17928169, GO:0003674=GO_REF:0000015, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0004842=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002} Q9UH90 F-box only protein 40 protein 20101115 {GO:0042692=ISS, GO:0003674=ND, GO:0005813=IDA, GO:0005737=IDA, GO:0004842=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA} muscle cell differentiation centrosome, cytoplasm, nucleolus, nucleus molecular_function, ubiquitin-protein ligase activity, zinc ion binding Human FBXO41 null null {} null null null null {} null null null FBXO42 null null {} null null null null {} null null null FBXO44 UniProtKB UniProtKB {GO:0005515=PMID:18203720, GO:0030163=GO_REF:0000002, GO:0019005=PMID:18203720} Q9H4M3 F-box only protein 44 protein 20100614 {GO:0005515=IPI, GO:0030163=IEA, GO:0019005=IDA} protein catabolic process SCF ubiquitin ligase complex protein binding Human UniProtKB:Q13616 FBXO45 UniProtKB UniProtKB {GO:0005515=PMID:19581926, GO:0042734=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0016567=GO_REF:0000024, GO:0042787=PMID:19581926, GO:0005886=GO_REF:0000037, GO:0045211=GO_REF:0000039, GO:0014069=GO_REF:0000019, GO:0043161=GO_REF:0000024, GO:0006974=PMID:19581926, GO:0007399=GO_REF:0000037} P0C2W1 F-box/SPRY domain-containing protein 1 protein 20100629 {GO:0005515=IPI, GO:0042734=IEA, GO:0030054=IEA, GO:0016567=ISS, GO:0042787=IDA, GO:0005886=IEA, GO:0045211=IEA, GO:0014069=IEA, GO:0043161=ISS, GO:0006974=IDA, GO:0007399=IEA} nervous system development, proteasomal ubiquitin-dependent protein catabolic process, protein ubiquitination, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, response to DNA damage stimulus cell junction, plasma membrane, postsynaptic density, postsynaptic membrane, presynaptic membrane protein binding Human UniProtKB:Q8K3B1 FBXO46 IntAct UniProtKB {GO:0005515=PMID:22632967} Q6PJ61 F-box only protein 46 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:P63208 FBXO5 HPA UniProtKB {GO:0005515=PMID:18662541, GO:0005634=GO_REF:0000052, GO:0001556=GO_REF:0000019, GO:0031145=Reactome:REACT_6828, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_6878, GO:0016050=GO_REF:0000019, GO:0007057=GO_REF:0000019, GO:0005737=PMID:11988738, GO:0000082=Reactome:REACT_1783, GO:0000083=Reactome:REACT_683, GO:0000089=GO_REF:0000019, GO:0000087=Reactome:REACT_910, GO:0007091=Reactome:REACT_1016, GO:0019901=PMID:15148369, GO:0060565=PMID:15148369, GO:0005730=GO_REF:0000052, GO:0005819=PMID:15469984, GO:0051437=Reactome:REACT_6821, GO:0051436=PMID:16921029, GO:0051439=Reactome:REACT_6837, GO:0040020=GO_REF:0000019, GO:0007346=GO_REF:0000024, GO:0046785=GO_REF:0000019, GO:0005654=Reactome:REACT_22145, GO:0000278=Reactome:REACT_152, GO:0051301=GO_REF:0000037} Q9UKT4 F-box only protein 5 protein 20111111 {GO:0005515=IPI, GO:0005634=IDA, GO:0001556=IEA, GO:0031145=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0016050=IEA, GO:0007057=IEA, GO:0005737=IDA, GO:0000082=TAS, GO:0000083=TAS, GO:0000089=IEA, GO:0000087=TAS, GO:0007091=TAS, GO:0019901=IPI, GO:0060565=IDA, GO:0005730=IDA, GO:0005819=IDA, GO:0051437=TAS, GO:0051436=IDA, GO:0051439=TAS, GO:0040020=IEA, GO:0007346=ISS, GO:0046785=IEA, GO:0005654=TAS, GO:0000278=TAS, GO:0051301=IEA} G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell division, inhibition of mitotic anaphase-promoting complex activity, metaphase/anaphase transition of mitotic cell cycle, microtubule polymerization, mitotic cell cycle, mitotic metaphase, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, oocyte maturation, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, regulation of meiosis, regulation of mitotic cell cycle, regulation of transcription involved in G1/S phase of mitotic cell cycle, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, spindle assembly involved in female meiosis I, vesicle organization cytoplasm, cytosol, nucleolus, nucleoplasm, nucleus, spindle metal ion binding, protein binding, protein kinase binding NOT Human FBXO6 PINC UniProtKB {GO:0006986=GO_REF:0000037, GO:0005515=PMID:19716789, GO:0004842=GO_REF:0000019, GO:0031146=PMID:19716789, GO:0030433=GO_REF:0000024, GO:0030163=GO_REF:0000002, GO:0005737=PMID:19716789, GO:0006281=PMID:19716789, GO:0001948=GO_REF:0000024, GO:0006508=PMID:10531035, GO:0006516=GO_REF:0000019, GO:0030246=GO_REF:0000019, GO:0000077=PMID:19716789, GO:0019005=PMID:19716789} Q9NRD1 F-box only protein 6 protein 20050308 {GO:0006986=IEA, GO:0005515=IPI, GO:0004842=IEA, GO:0031146=IDA, GO:0030433=ISS, GO:0030163=IEA, GO:0005737=IDA, GO:0006281=TAS, GO:0001948=ISS, GO:0006508=TAS, GO:0006516=IEA, GO:0030246=IEA, GO:0000077=TAS, GO:0019005=IDA} DNA damage checkpoint, DNA repair, ER-associated protein catabolic process, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, glycoprotein catabolic process, protein catabolic process, proteolysis, response to unfolded protein SCF ubiquitin ligase complex, cytoplasm carbohydrate binding, glycoprotein binding, protein binding, ubiquitin-protein ligase activity Human FBXO7 IntAct UniProtKB {GO:0005515=PMID:22632967, GO:0043234=GO_REF:0000054, GO:0006511=PMID:10531035, GO:0008219=GO_REF:0000037, GO:0004842=PMID:10531035, GO:0005737=GO_REF:0000039, GO:0031647=PMID:15145941, GO:0000151=PMID:10531035, GO:0005634=GO_REF:0000039} Q9Y3I1 F-box only protein 7 protein 20130415 {GO:0005515=IPI, GO:0043234=IDA, GO:0006511=TAS, GO:0008219=IEA, GO:0004842=TAS, GO:0005737=IEA, GO:0031647=IDA, GO:0000151=TAS, GO:0005634=IEA} cell death, regulation of protein stability, ubiquitin-dependent protein catabolic process cytoplasm, nucleus, protein complex, ubiquitin ligase complex protein binding, ubiquitin-protein ligase activity Human UniProtKB:P63208 FBXO8 UniProtKB UniProtKB {GO:0005802=GO_REF:0000033, GO:0005086=GO_REF:0000029, GO:0006511=PMID:10945468, GO:0030054=GO_REF:0000033, GO:0030036=GO_REF:0000033, GO:0032012=GO_REF:0000002, GO:0000151=PMID:10945468, GO:0005634=GO_REF:0000033, GO:0016192=GO_REF:0000033} Q9NRD0 F-box only protein 8 protein 20021104 {GO:0005802=IBA, GO:0005086=NAS, GO:0006511=NAS, GO:0030054=IBA, GO:0030036=IBA, GO:0032012=IEA, GO:0000151=NAS, GO:0005634=IBA, GO:0016192=IBA} actin cytoskeleton organization, regulation of ARF protein signal transduction, ubiquitin-dependent protein catabolic process, vesicle-mediated transport cell junction, nucleus, trans-Golgi network, ubiquitin ligase complex ARF guanyl-nucleotide exchange factor activity Human FBXO9 UniProtKB UniProtKB {GO:0005515=PMID:23263282, GO:0032006=PMID:23263282, GO:0005737=PMID:23263282, GO:0004842=PMID:10531037, GO:0016567=PMID:23263282, GO:0000151=PMID:10531037, GO:0031146=PMID:23263282, GO:0019005=PMID:23263282} Q9UK97 F-box only protein 9 protein 20130125 {GO:0005515=IPI, GO:0032006=IMP, GO:0005737=IDA, GO:0004842=NAS, GO:0016567=IDA, GO:0000151=NAS, GO:0031146=IDA, GO:0019005=IDA} SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, protein ubiquitination, regulation of TOR signaling cascade SCF ubiquitin ligase complex, cytoplasm, ubiquitin ligase complex protein binding, ubiquitin-protein ligase activity Human UniProtKB:O43156 FBXW10 null null {} null null null null {} null null null FBXW11 IntAct UniProtKB {GO:0000209=PMID:20347421, GO:0005515=PMID:22682247, GO:0005813=PMID:21399614, GO:0042347=GO_REF:0000019, GO:0004842=PMID:20347421, GO:0016567=PMID:16885022, GO:0000151=PMID:10531035, GO:0005634=GO_REF:0000024, GO:0031146=PMID:20347421, GO:0045862=PMID:16885022, GO:0005829=Reactome:REACT_118856, GO:0031648=PMID:16885022, GO:0007049=GO_REF:0000037, GO:0006470=GO_REF:0000024, GO:0042753=GO_REF:0000024, GO:0046983=GO_REF:0000002, GO:0043161=PMID:20347421, GO:0048511=GO_REF:0000037, GO:0045893=GO_REF:0000024, GO:0016055=GO_REF:0000037, GO:0045892=PMID:19966869, GO:0019005=PMID:20347421} Q9UKB1 F-box/WD repeat-containing protein 11 protein 20130415 {GO:0000209=IDA, GO:0005515=IPI, GO:0005813=IDA, GO:0042347=IEA, GO:0004842=IDA, GO:0016567=IDA, GO:0000151=NAS, GO:0005634=ISS, GO:0031146=IDA, GO:0045862=IMP, GO:0005829=TAS, GO:0031648=IMP, GO:0007049=IEA, GO:0006470=ISS, GO:0042753=ISS, GO:0046983=IEA, GO:0043161=IDA, GO:0048511=IEA, GO:0045893=ISS, GO:0016055=IEA, GO:0045892=IMP, GO:0019005=IDA} SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, Wnt receptor signaling pathway, cell cycle, negative regulation of NF-kappaB import into nucleus, negative regulation of transcription, DNA-dependent, positive regulation of circadian rhythm, positive regulation of proteolysis, positive regulation of transcription, DNA-dependent, proteasomal ubiquitin-dependent protein catabolic process, protein dephosphorylation, protein destabilization, protein polyubiquitination, protein ubiquitination, rhythmic process SCF ubiquitin ligase complex, centrosome, cytosol, nucleus, ubiquitin ligase complex protein binding, protein dimerization activity, ubiquitin-protein ligase activity Human UniProtKB:P35222 FBXW2 GOC UniProtKB {GO:0005515=PMID:22632967, GO:0004842=PMID:10531035, GO:0005737=GO_REF:0000019, GO:0016567=PMID:10531035, GO:0006508=PMID:10531035, GO:0006464=PMID:10531035} Q9UKT8 F-box/WD repeat-containing protein 2 protein 20130413 {GO:0005515=IPI, GO:0004842=TAS, GO:0005737=IEA, GO:0016567=TAS, GO:0006508=TAS, GO:0006464=TAS} cellular protein modification process, protein ubiquitination, proteolysis cytoplasm protein binding, ubiquitin-protein ligase activity Human FBXW4 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0006511=PMID:10945468, GO:0051216=GO_REF:0000019, GO:0000151=PMID:10945468, GO:0002053=GO_REF:0000019, GO:0030326=PMID:10405324, GO:0016055=GO_REF:0000037, GO:0042733=GO_REF:0000019} P57775 F-box/WD repeat-containing protein 4 protein 20011009 {GO:0003674=ND, GO:0006511=NAS, GO:0051216=IEA, GO:0000151=NAS, GO:0002053=IEA, GO:0030326=NAS, GO:0016055=IEA, GO:0042733=IEA} Wnt receptor signaling pathway, cartilage development, embryonic digit morphogenesis, embryonic limb morphogenesis, positive regulation of mesenchymal cell proliferation, ubiquitin-dependent protein catabolic process ubiquitin ligase complex molecular_function Human FBXW5 IntAct UniProtKB {GO:0005515=PMID:22632967, GO:0051298=PMID:21725316, GO:0005737=PMID:21725316, GO:0016567=PMID:21725316, GO:0019901=PMID:21725316, GO:0043161=PMID:18381890, GO:0080008=PMID:18381890, GO:0031146=PMID:21725316, GO:0003824=GO_REF:0000002, GO:0019005=PMID:21725316} Q969U6 F-box/WD repeat-containing protein 5 protein 20130415 {GO:0005515=IPI, GO:0051298=IMP, GO:0005737=IDA, GO:0016567=IDA, GO:0019901=IPI, GO:0043161=IDA, GO:0080008=IDA, GO:0031146=IDA, GO:0003824=IEA, GO:0019005=IDA} SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, centrosome duplication, proteasomal ubiquitin-dependent protein catabolic process, protein ubiquitination Cul4-RING ubiquitin ligase complex, SCF ubiquitin ligase complex, cytoplasm catalytic activity, protein binding, protein kinase binding Human UniProtKB:P63208 FBXW7 BHF-UCL UniProtKB {GO:0005515=PMID:17314511, GO:0016567=PMID:12354302, GO:0003700=GO_REF:0000019, GO:0030324=GO_REF:0000019, GO:0005783=GO_REF:0000019, GO:0032876=PMID:15917200, GO:0031146=PMID:15103331, GO:2000639=GO_REF:0000024, GO:0032880=GO_REF:0000024, GO:0007219=Reactome:REACT_118859, GO:0070374=PMID:20208556, GO:0001944=PMID:21123947, GO:0045746=GO_REF:0000024, GO:0010868=GO_REF:0000024, GO:0005794=GO_REF:0000019, GO:0045741=PMID:20208556, GO:0005730=GO_REF:0000039, GO:0050821=PMID:20208556, GO:2000346=GO_REF:0000024, GO:0055088=GO_REF:0000024, GO:0010883=GO_REF:0000024, GO:2000060=PMID:20208556, GO:0019048=GO_REF:0000037, GO:0007062=PMID:15917200, GO:0005654=Reactome:REACT_160209, GO:0001570=GO_REF:0000019, GO:0019005=PMID:15103331} Q969H0 F-box/WD repeat-containing protein 7 protein 20100127 {GO:0005515=IPI, GO:0016567=IDA, GO:0003700=IEA, GO:0030324=IEA, GO:0005783=IEA, GO:0032876=IMP, GO:0031146=IDA, GO:2000639=ISS, GO:0032880=ISS, GO:0007219=TAS, GO:0070374=IMP, GO:0001944=TAS, GO:0045746=ISS, GO:0010868=ISS, GO:0005794=IEA, GO:0045741=IDA, GO:0005730=IEA, GO:0050821=IDA, GO:2000346=ISS, GO:0055088=ISS, GO:0010883=ISS, GO:2000060=IDA, GO:0019048=IEA, GO:0007062=IMP, GO:0005654=TAS, GO:0001570=IEA, GO:0019005=IDA} Notch signaling pathway, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, lipid homeostasis, lung development, negative regulation of DNA endoreduplication, negative regulation of Notch signaling pathway, negative regulation of SREBP signaling pathway, negative regulation of hepatocyte proliferation, negative regulation of triglyceride biosynthetic process, positive regulation of ERK1 and ERK2 cascade, positive regulation of epidermal growth factor-activated receptor activity, positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process, protein stabilization, protein ubiquitination, regulation of lipid storage, regulation of protein localization, sister chromatid cohesion, vasculature development, vasculogenesis, virus-host interaction Golgi apparatus, SCF ubiquitin ligase complex, endoplasmic reticulum, nucleolus, nucleoplasm protein binding, sequence-specific DNA binding transcription factor activity Human FBXW8 IntAct UniProtKB {GO:0005515=PMID:17314511, GO:0048471=GO_REF:0000039, GO:0005794=GO_REF:0000039, GO:0060712=GO_REF:0000019, GO:0060716=GO_REF:0000019, GO:0019005=GO_REF:0000019} Q8N3Y1 F-box/WD repeat-containing protein 8 protein 20130415 {GO:0005515=IPI, GO:0048471=IEA, GO:0005794=IEA, GO:0060712=IEA, GO:0060716=IEA, GO:0019005=IEA} labyrinthine layer blood vessel development, spongiotrophoblast layer development Golgi apparatus, SCF ubiquitin ligase complex, perinuclear region of cytoplasm protein binding Human UniProtKB:P01106 FBXW9 IntAct UniProtKB {GO:0005515=PMID:19159283} Q5XUX1 F-box/WD repeat-containing protein 9 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:P63208 FCAMR UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q8WWV6 High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor protein 20130413 {GO:0005886=IEA, GO:0016021=IEA} integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 FCAR HPA UniProtKB {GO:0006955=PMID:10835685, GO:0019862=GO_REF:0000037, GO:0005886=GO_REF:0000052, GO:0005887=PMID:2258698, GO:0005576=GO_REF:0000039} P24071 Immunoglobulin alpha Fc receptor protein 20090616 {GO:0006955=TAS, GO:0019862=IEA, GO:0005886=IDA, GO:0005887=TAS, GO:0005576=IEA} immune response extracellular region, integral to plasma membrane, plasma membrane IgA binding Human FCER1A PINC UniProtKB {GO:0001812=GO_REF:0000019, GO:0019370=GO_REF:0000019, GO:0045401=GO_REF:0000019, GO:0001820=GO_REF:0000019, GO:0045425=GO_REF:0000019, GO:0005886=PMID:1535625, GO:0050731=GO_REF:0000019, GO:0007257=GO_REF:0000019, GO:0043306=GO_REF:0000019, GO:0050850=GO_REF:0000019, GO:0019863=GO_REF:0000019, GO:0005887=GO_REF:0000019, GO:0019767=GO_REF:0000019, GO:0009897=GO_REF:0000019} P12319 High affinity immunoglobulin epsilon receptor subunit alpha protein 20030904 {GO:0001812=IEA, GO:0019370=IEA, GO:0045401=IEA, GO:0001820=IEA, GO:0045425=IEA, GO:0005886=TAS, GO:0050731=IEA, GO:0007257=IEA, GO:0043306=IEA, GO:0050850=IEA, GO:0019863=IEA, GO:0005887=IEA, GO:0019767=IEA, GO:0009897=IEA} activation of JUN kinase activity, leukotriene biosynthetic process, positive regulation of calcium-mediated signaling, positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, positive regulation of interleukin-3 biosynthetic process, positive regulation of mast cell degranulation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of type I hypersensitivity, serotonin secretion external side of plasma membrane, integral to plasma membrane, plasma membrane IgE binding, IgE receptor activity Human FCER1G Reactome UniProtKB {GO:0001812=GO_REF:0000019, GO:0032755=GO_REF:0000019, GO:0033026=GO_REF:0000019, GO:0045576=GO_REF:0000019, GO:0016064=GO_REF:0000019, GO:0005886=Reactome:REACT_23800, GO:0032733=GO_REF:0000019, GO:0010543=GO_REF:0000019, GO:0050900=Reactome:REACT_12051, GO:0002554=GO_REF:0000019, GO:0019886=GO_REF:0000019, GO:0032998=GO_REF:0000019, GO:0050766=GO_REF:0000019, GO:0019863=GO_REF:0000019, GO:0019864=GO_REF:0000019, GO:0001798=GO_REF:0000019, GO:0019767=GO_REF:0000019, GO:0002283=GO_REF:0000019, GO:0042742=GO_REF:0000019, GO:0032765=GO_REF:0000019, GO:0032760=GO_REF:0000019, GO:0030593=GO_REF:0000019, GO:0042590=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0006911=GO_REF:0000019, GO:0001805=GO_REF:0000019, GO:0043306=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0007229=GO_REF:0000019, GO:0005887=GO_REF:0000019, GO:0002431=GO_REF:0000019, GO:0009897=GO_REF:0000019} P30273 High affinity immunoglobulin epsilon receptor subunit gamma protein 20130213 {GO:0001812=IEA, GO:0032755=IEA, GO:0033026=IEA, GO:0045576=IEA, GO:0016064=IEA, GO:0005886=TAS, GO:0032733=IEA, GO:0010543=IEA, GO:0050900=TAS, GO:0002554=IEA, GO:0019886=IEA, GO:0032998=IEA, GO:0050766=IEA, GO:0019863=IEA, GO:0019864=IEA, GO:0001798=IEA, GO:0019767=IEA, GO:0002283=IEA, GO:0042742=IEA, GO:0032765=IEA, GO:0032760=IEA, GO:0030593=IEA, GO:0042590=IEA, GO:0030168=TAS, GO:0006911=IEA, GO:0001805=IEA, GO:0043306=IEA, GO:0007596=TAS, GO:0007229=IEA, GO:0005887=IEA, GO:0002431=IEA, GO:0009897=IEA} Fc receptor mediated stimulatory signaling pathway, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class II, blood coagulation, defense response to bacterium, immunoglobulin mediated immune response, integrin-mediated signaling pathway, leukocyte migration, mast cell activation, negative regulation of mast cell apoptotic process, neutrophil activation involved in immune response, neutrophil chemotaxis, phagocytosis, engulfment, platelet activation, positive regulation of interleukin-10 production, positive regulation of interleukin-6 production, positive regulation of mast cell cytokine production, positive regulation of mast cell degranulation, positive regulation of phagocytosis, positive regulation of tumor necrosis factor production, positive regulation of type I hypersensitivity, positive regulation of type III hypersensitivity, positive regulation of type IIa hypersensitivity, regulation of platelet activation, serotonin secretion by platelet Fc-epsilon receptor I complex, external side of plasma membrane, integral to plasma membrane, plasma membrane IgE binding, IgE receptor activity, IgG binding Human FCER2 BHF-UCL UniProtKB {GO:0002925=GO_REF:0000019, GO:0019863=GO_REF:0000037, GO:0005178=PMID:2529542, GO:0051000=PMID:7544003, GO:0005887=PMID:2529542, GO:0051712=PMID:7544003, GO:0030246=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0051770=PMID:7544003, GO:0009897=GO_REF:0000019, GO:0046872=GO_REF:0000037} P06734 Low affinity immunoglobulin epsilon Fc receptor protein 20080724 {GO:0002925=IEA, GO:0019863=IEA, GO:0005178=TAS, GO:0051000=IDA, GO:0005887=TAS, GO:0051712=IDA, GO:0030246=IEA, GO:0005576=IEA, GO:0051770=IDA, GO:0009897=IEA, GO:0046872=IEA} positive regulation of humoral immune response mediated by circulating immunoglobulin, positive regulation of killing of cells of other organism, positive regulation of nitric-oxide synthase activity, positive regulation of nitric-oxide synthase biosynthetic process external side of plasma membrane, extracellular region, integral to plasma membrane IgE binding, carbohydrate binding, integrin binding, metal ion binding Human FCGBP HPA UniProtKB {GO:0005515=PMID:19432394, GO:0005737=GO_REF:0000052, GO:0005576=GO_REF:0000039} Q9Y6R7 IgGFc-binding protein protein 20080205 {GO:0005515=IPI, GO:0005737=IDA, GO:0005576=IEA} cytoplasm, extracellular region protein binding Human FCGR1A BHF-UCL UniProtKB {GO:0005515=PMID:18322202, GO:0002474=Reactome:REACT_75820, GO:0005886=PMID:18322202, GO:0019221=Reactome:REACT_25229, GO:0050766=GO_REF:0000019, GO:0006955=PMID:10879688, GO:0019864=GO_REF:0000019, GO:0001798=GO_REF:0000019, GO:0042742=GO_REF:0000019, GO:0060333=Reactome:REACT_25078, GO:0042590=Reactome:REACT_111119, GO:0006910=GO_REF:0000019, GO:0006911=GO_REF:0000019, GO:0006898=GO_REF:0000019, GO:0001805=GO_REF:0000019, GO:0007165=PMID:10879688, GO:0031901=Reactome:REACT_111177, GO:0045087=Reactome:REACT_6802, GO:0002479=Reactome:REACT_111056, GO:0016021=GO_REF:0000037, GO:0005057=PMID:10879688, GO:0019770=GO_REF:0000019, GO:0030669=Reactome:REACT_111177, GO:0038096=Reactome:REACT_160123, GO:0001788=GO_REF:0000019, GO:0009897=GO_REF:0000019} P12314 High affinity immunoglobulin gamma Fc receptor I protein 20080926 {GO:0005515=IPI, GO:0002474=TAS, GO:0005886=IDA, GO:0019221=TAS, GO:0050766=IEA, GO:0006955=TAS, GO:0019864=IEA, GO:0001798=IEA, GO:0042742=IEA, GO:0060333=TAS, GO:0042590=TAS, GO:0006910=IEA, GO:0006911=IEA, GO:0006898=IEA, GO:0001805=IEA, GO:0007165=TAS, GO:0031901=TAS, GO:0045087=TAS, GO:0002479=TAS, GO:0016021=IEA, GO:0005057=TAS, GO:0019770=IEA, GO:0030669=TAS, GO:0038096=TAS, GO:0001788=IEA, GO:0009897=IEA} Fc-gamma receptor signaling pathway involved in phagocytosis, antibody-dependent cellular cytotoxicity, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, cytokine-mediated signaling pathway, defense response to bacterium, immune response, innate immune response, interferon-gamma-mediated signaling pathway, phagocytosis, engulfment, phagocytosis, recognition, positive regulation of phagocytosis, positive regulation of type III hypersensitivity, positive regulation of type IIa hypersensitivity, receptor-mediated endocytosis, signal transduction clathrin-coated endocytic vesicle membrane, early endosome membrane, external side of plasma membrane, integral to membrane, plasma membrane IgG binding, IgG receptor activity, protein binding, receptor signaling protein activity Human FCGR2A Reactome UniProtKB {GO:0005886=Reactome:REACT_160316, GO:0019864=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0016021=GO_REF:0000037, GO:0038096=Reactome:REACT_160123} P12318 Low affinity immunoglobulin gamma Fc region receptor II-a protein 20120104 {GO:0005886=TAS, GO:0019864=IEA, GO:0045087=TAS, GO:0016021=IEA, GO:0038096=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, innate immune response integral to membrane, plasma membrane IgG binding Human FCGR2B IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0007165=PMID:2142460, GO:0006955=PMID:2142460, GO:0005886=Reactome:REACT_11087, GO:0019864=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0050776=Reactome:REACT_11152, GO:0016021=GO_REF:0000037} P31994 Low affinity immunoglobulin gamma Fc region receptor II-b protein 20130415 {GO:0005515=IPI, GO:0007165=TAS, GO:0006955=TAS, GO:0005886=TAS, GO:0019864=IEA, GO:0019048=IEA, GO:0050776=TAS, GO:0016021=IEA} immune response, regulation of immune response, signal transduction, virus-host interaction integral to membrane, plasma membrane IgG binding, protein binding Human UniProtKB:P19174 FCGR2C IntAct UniProtKB {GO:0005515=PMID:17785206, GO:0006955=PMID:2531080, GO:0005737=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0019864=GO_REF:0000037, GO:0016021=PMID:2531080, GO:0004888=PMID:2531080} P31995 Low affinity immunoglobulin gamma Fc region receptor II-c protein 20130415 {GO:0005515=IPI, GO:0006955=NAS, GO:0005737=IEA, GO:0005886=IEA, GO:0019864=IEA, GO:0016021=NAS, GO:0004888=NAS} immune response cytoplasm, integral to membrane, plasma membrane IgG binding, protein binding, transmembrane signaling receptor activity Human UniProtKB:P02741 FCGR3A Reactome UniProtKB {GO:0006955=PMID:2138330, GO:0005886=Reactome:REACT_160316, GO:0019864=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0050776=Reactome:REACT_11152, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0038096=Reactome:REACT_160123} P08637 Low affinity immunoglobulin gamma Fc region receptor III-A protein 20130228 {GO:0006955=TAS, GO:0005886=TAS, GO:0019864=IEA, GO:0045087=TAS, GO:0050776=TAS, GO:0005576=IEA, GO:0016021=IEA, GO:0038096=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, immune response, innate immune response, regulation of immune response extracellular region, integral to membrane, plasma membrane IgG binding Human FCGR3B PINC UniProtKB {GO:0006955=PMID:2139735, GO:0005886=GO_REF:0000039, GO:0019864=GO_REF:0000037, GO:0005576=GO_REF:0000039, GO:0031225=GO_REF:0000037} O75015 Low affinity immunoglobulin gamma Fc region receptor III-B protein 20030904 {GO:0006955=TAS, GO:0005886=IEA, GO:0019864=IEA, GO:0005576=IEA, GO:0031225=IEA} immune response anchored to membrane, extracellular region, plasma membrane IgG binding Human FCGRT UniProtKB UniProtKB {GO:0030881=GO_REF:0000019, GO:0006955=GO_REF:0000002, GO:0019864=PMID:7964511, GO:0002416=PMID:7964511, GO:0019882=GO_REF:0000002, GO:0042612=GO_REF:0000002, GO:0016021=GO_REF:0000037} P55899 IgG receptor FcRn large subunit p51 protein 20130307 {GO:0030881=IEA, GO:0006955=IEA, GO:0019864=IDA, GO:0002416=NAS, GO:0019882=IEA, GO:0042612=IEA, GO:0016021=IEA} IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor, antigen processing and presentation, immune response MHC class I protein complex, integral to membrane IgG binding, beta-2-microglobulin binding Human FCHO1 MGI UniProtKB {GO:0072583=PMID:20448150, GO:0005905=PMID:22484487, GO:0005886=PMID:20448150, GO:0035612=PMID:22484487, GO:0030136=PMID:20448150, GO:0048268=PMID:20448150} O14526 FCH domain only protein 1 protein 20120730 {GO:0072583=IMP, GO:0005905=IDA, GO:0005886=IDA, GO:0035612=IDA, GO:0030136=IDA, GO:0048268=IMP} clathrin coat assembly, clathrin-mediated endocytosis clathrin-coated vesicle, coated pit, plasma membrane AP-2 adaptor complex binding Human FCHO2 IntAct UniProtKB {GO:0005515=PMID:22323290, GO:0072583=PMID:20448150, GO:0005905=PMID:22484487, GO:0005886=GO_REF:0000024, GO:0030136=PMID:21762413, GO:0001786=GO_REF:0000024, GO:0005546=GO_REF:0000024, GO:0035091=GO_REF:0000024, GO:0072659=GO_REF:0000024, GO:0010324=GO_REF:0000024, GO:0048268=PMID:20448150} Q0JRZ9 FCH domain only protein 2 protein 20130415 {GO:0005515=IPI, GO:0072583=IMP, GO:0005905=IDA, GO:0005886=ISS, GO:0030136=IDA, GO:0001786=ISS, GO:0005546=ISS, GO:0035091=ISS, GO:0072659=ISS, GO:0010324=ISS, GO:0048268=IMP} clathrin coat assembly, clathrin-mediated endocytosis, membrane invagination, protein localization to plasma membrane clathrin-coated vesicle, coated pit, plasma membrane phosphatidylinositol binding, phosphatidylinositol-4,5-bisphosphate binding, phosphatidylserine binding, protein binding Human UniProtKB:P98078 FCHSD1 null null {} null null null null {} null null null FCHSD2 IntAct UniProtKB {GO:0005515=PMID:18654987} O94868 FCH and double SH3 domains protein 2 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:P55072 FCN1 PINC UniProtKB {GO:0005581=GO_REF:0000037, GO:0045087=GO_REF:0000037, GO:0005509=PMID:8576206, GO:0030246=PMID:8576206, GO:0003823=PMID:8576206, GO:0008228=PMID:8576206} O00602 Ficolin-1 protein 20030904 {GO:0005581=IEA, GO:0045087=IEA, GO:0005509=TAS, GO:0030246=TAS, GO:0003823=TAS, GO:0008228=TAS} innate immune response, opsonization collagen antigen binding, calcium ion binding, carbohydrate binding Human FCN2 PINC UniProtKB {GO:0005581=GO_REF:0000037, GO:0005509=PMID:8576206, GO:0030246=PMID:8576206, GO:0003823=PMID:8576206, GO:0008228=PMID:8576206, GO:0048306=PMID:12421953, GO:0001867=GO_REF:0000037} Q15485 Ficolin-2 protein 20031106 {GO:0005581=IEA, GO:0005509=TAS, GO:0030246=TAS, GO:0003823=TAS, GO:0008228=TAS, GO:0048306=IPI, GO:0001867=IEA} complement activation, lectin pathway, opsonization collagen antigen binding, calcium ion binding, calcium-dependent protein binding, carbohydrate binding Human FCN3 PINC UniProtKB {GO:0005515=PMID:11907111, GO:0005581=GO_REF:0000037, GO:0030246=PMID:9694814, GO:0005576=PMID:14718574, GO:0001867=PMID:11907111} O75636 Ficolin-3 protein 20031119 {GO:0005515=IPI, GO:0005581=IEA, GO:0030246=TAS, GO:0005576=NAS, GO:0001867=IDA} complement activation, lectin pathway collagen, extracellular region carbohydrate binding, protein binding Human FCRL3 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q96P31 Fc receptor-like protein 3 protein 20130413 {GO:0005886=IEA, GO:0016021=IEA} integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 FCRLB MGI UniProtKB {GO:0005737=PMID:15815692, GO:0005783=GO_REF:0000039} Q6BAA4 Fc receptor-like B protein 20091111 {GO:0005737=IDA, GO:0005783=IEA} cytoplasm, endoplasmic reticulum Human FDFT1 HPA UniProtKB {GO:0006695=Reactome:REACT_9405, GO:0008610=GO_REF:0000002, GO:0006694=PMID:8474436, GO:0009058=GO_REF:0000002, GO:0051996=GO_REF:0000003, GO:0005783=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0008299=GO_REF:0000037, GO:0043231=GO_REF:0000019, GO:0045338=GO_REF:0000019, GO:0016491=GO_REF:0000037, GO:0005789=Reactome:REACT_115945, GO:0016021=GO_REF:0000037, GO:0044255=Reactome:REACT_22279, GO:0016740=GO_REF:0000002, GO:0004310=Reactome:REACT_9512} P37268 Squalene synthase protein 20080818 {GO:0006695=TAS, GO:0008610=IEA, GO:0006694=TAS, GO:0009058=IEA, GO:0051996=IEA, GO:0005783=IDA, GO:0044281=TAS, GO:0008299=IEA, GO:0043231=IEA, GO:0045338=IEA, GO:0016491=IEA, GO:0005789=TAS, GO:0016021=IEA, GO:0044255=TAS, GO:0016740=IEA, GO:0004310=TAS} biosynthetic process, cellular lipid metabolic process, cholesterol biosynthetic process, farnesyl diphosphate metabolic process, isoprenoid biosynthetic process, lipid biosynthetic process, small molecule metabolic process, steroid biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle farnesyl-diphosphate farnesyltransferase activity, oxidoreductase activity, squalene synthase activity, transferase activity Human FDPS HPA UniProtKB {GO:0006695=Reactome:REACT_9405, GO:0005730=GO_REF:0000052, GO:0004337=GO_REF:0000003, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0008299=GO_REF:0000038, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_147807, GO:0005739=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0019048=GO_REF:0000037, GO:0045337=GO_REF:0000041, GO:0004161=GO_REF:0000003, GO:0033384=GO_REF:0000041, GO:0016740=GO_REF:0000038} P14324 Farnesyl pyrophosphate synthase protein 20101115 {GO:0006695=TAS, GO:0005730=IDA, GO:0004337=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0008299=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0005737=IDA, GO:0019048=IEA, GO:0045337=IEA, GO:0004161=IEA, GO:0033384=IEA, GO:0016740=IEA} cholesterol biosynthetic process, farnesyl diphosphate biosynthetic process, geranyl diphosphate biosynthetic process, isoprenoid biosynthetic process, small molecule metabolic process, virus-host interaction cytoplasm, cytosol, mitochondrion, nucleolus, nucleus dimethylallyltranstransferase activity, geranyltranstransferase activity, metal ion binding, transferase activity Human FDX1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0006694=GO_REF:0000037, GO:0005506=PMID:2969697, GO:0051537=PMID:21636783, GO:0005759=Reactome:REACT_150385, GO:0009055=PMID:21636783, GO:0042446=PMID:21636783, GO:0044281=Reactome:REACT_111217, GO:0022900=GO_REF:0000037, GO:0008203=PMID:21636783} P10109 Adrenodoxin, mitochondrial protein 20110516 {GO:0005739=IDA, GO:0006694=IEA, GO:0005506=TAS, GO:0051537=IDA, GO:0005759=TAS, GO:0009055=IDA, GO:0042446=IDA, GO:0044281=TAS, GO:0022900=IEA, GO:0008203=IDA} cholesterol metabolic process, electron transport chain, hormone biosynthetic process, small molecule metabolic process, steroid biosynthetic process mitochondrial matrix, mitochondrion 2 iron, 2 sulfur cluster binding, electron carrier activity, iron ion binding Human FDX1L Reactome UniProtKB {GO:0051537=GO_REF:0000037, GO:0005759=Reactome:REACT_150385, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0022900=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q6P4F2 Adrenodoxin-like protein, mitochondrial protein 20120702 {GO:0051537=IEA, GO:0005759=TAS, GO:0009055=IEA, GO:0044281=TAS, GO:0022900=IEA, GO:0046872=IEA} electron transport chain, small molecule metabolic process mitochondrial matrix 2 iron, 2 sulfur cluster binding, electron carrier activity, metal ion binding Human FDXACB1 InterPro UniProtKB {GO:0000287=GO_REF:0000002, GO:0000049=GO_REF:0000002, GO:0006432=GO_REF:0000002, GO:0004826=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0008033=GO_REF:0000002} Q9BRP7 Ferredoxin-fold anticodon-binding domain-containing protein 1 protein 20130413 {GO:0000287=IEA, GO:0000049=IEA, GO:0006432=IEA, GO:0004826=IEA, GO:0005524=IEA, GO:0008033=IEA} phenylalanyl-tRNA aminoacylation, tRNA processing ATP binding, magnesium ion binding, phenylalanine-tRNA ligase activity, tRNA binding Human InterPro:IPR005121 FDXR IntAct UniProtKB {GO:0005515=PMID:18319262, GO:0006694=PMID:1863359, GO:0005743=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0006091=PMID:2845396, GO:0070402=GO_REF:0000019, GO:0070995=GO_REF:0000019, GO:0005739=PMID:2845396, GO:0004324=PMID:2845396, GO:0005759=Reactome:REACT_150376, GO:0015039=GO_REF:0000019, GO:0016491=GO_REF:0000038, GO:0022900=GO_REF:0000037, GO:0008203=GO_REF:0000041, GO:0055114=PMID:2845396} P22570 NADPH:adrenodoxin oxidoreductase, mitochondrial protein 20130415 {GO:0005515=IPI, GO:0006694=TAS, GO:0005743=IEA, GO:0044281=TAS, GO:0006091=TAS, GO:0070402=IEA, GO:0070995=IEA, GO:0005739=TAS, GO:0004324=TAS, GO:0005759=TAS, GO:0015039=IEA, GO:0016491=IEA, GO:0022900=IEA, GO:0008203=IEA, GO:0055114=TAS} NADPH oxidation, cholesterol metabolic process, electron transport chain, generation of precursor metabolites and energy, oxidation-reduction process, small molecule metabolic process, steroid biosynthetic process mitochondrial inner membrane, mitochondrial matrix, mitochondrion NADPH binding, NADPH-adrenodoxin reductase activity, ferredoxin-NADP+ reductase activity, oxidoreductase activity, protein binding Human UniProtKB:P49789 FECH BHF-UCL UniProtKB {GO:0005515=PMID:15123683, GO:0051537=GO_REF:0000037, GO:0005743=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0006091=PMID:1729699, GO:0010999=GO_REF:0000019, GO:0034379=GO_REF:0000019, GO:0055072=GO_REF:0000019, GO:0008198=PMID:1729699, GO:0004325=PMID:15123683, GO:0006783=Reactome:REACT_9465, GO:0006778=Reactome:REACT_9431, GO:0005759=Reactome:REACT_9461, GO:0030218=GO_REF:0000019, GO:0030350=GO_REF:0000019, GO:0046984=GO_REF:0000019, GO:0009416=PMID:1376018, GO:0046501=PMID:15123683, GO:0009589=GO_REF:0000019, GO:0008203=GO_REF:0000019, GO:0020037=GO_REF:0000019} P22830 Ferrochelatase, mitochondrial protein 20080912 {GO:0005515=IPI, GO:0051537=IEA, GO:0005743=IEA, GO:0044281=TAS, GO:0006091=TAS, GO:0010999=IEA, GO:0034379=IEA, GO:0055072=IEA, GO:0008198=TAS, GO:0004325=IDA, GO:0006783=TAS, GO:0006778=TAS, GO:0005759=TAS, GO:0030218=IEA, GO:0030350=IEA, GO:0046984=IEA, GO:0009416=TAS, GO:0046501=IDA, GO:0009589=IEA, GO:0008203=IEA, GO:0020037=IEA} cholesterol metabolic process, detection of UV, erythrocyte differentiation, generation of precursor metabolites and energy, heme biosynthetic process, iron ion homeostasis, porphyrin-containing compound metabolic process, protoporphyrinogen IX metabolic process, regulation of eIF2 alpha phosphorylation by heme, regulation of hemoglobin biosynthetic process, response to light stimulus, small molecule metabolic process, very-low-density lipoprotein particle assembly mitochondrial inner membrane, mitochondrial matrix 2 iron, 2 sulfur cluster binding, ferrochelatase activity, ferrous iron binding, heme binding, iron-responsive element binding, protein binding Human FEM1A UniProtKB UniProtKB {GO:0004842=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0050728=PMID:16424369, GO:0051438=GO_REF:0000024, GO:0031867=PMID:16424369} Q9BSK4 Protein fem-1 homolog A protein 20111220 {GO:0004842=ISS, GO:0005737=IEA, GO:0050728=IDA, GO:0051438=ISS, GO:0031867=IPI} negative regulation of inflammatory response, regulation of ubiquitin-protein ligase activity cytoplasm EP4 subtype prostaglandin E2 receptor binding, ubiquitin-protein ligase activity Human FEM1B HPA UniProtKB {GO:0005515=PMID:17003112, GO:0004842=PMID:15601820, GO:0016567=GO_REF:0000019, GO:0060743=GO_REF:0000019, GO:2000001=PMID:19330022, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0051438=PMID:15601820, GO:0042981=PMID:10542291, GO:0005634=GO_REF:0000052, GO:0005123=PMID:10542291, GO:0006917=PMID:10623617, GO:0060442=GO_REF:0000019, GO:0005737=PMID:19330022} Q9UK73 Protein fem-1 homolog B protein 20110516 {GO:0005515=IPI, GO:0004842=IMP, GO:0016567=IEA, GO:0060743=IEA, GO:2000001=IMP, GO:0005730=IDA, GO:0006915=IEA, GO:0051438=IMP, GO:0042981=IMP, GO:0005634=IDA, GO:0005123=IMP, GO:0006917=NAS, GO:0060442=IEA, GO:0005737=IDA} apoptotic process, branching involved in prostate gland morphogenesis, epithelial cell maturation involved in prostate gland development, induction of apoptosis, protein ubiquitination, regulation of DNA damage checkpoint, regulation of apoptotic process, regulation of ubiquitin-protein ligase activity cytoplasm, nucleolus, nucleus death receptor binding, protein binding, ubiquitin-protein ligase activity NOT Human FEM1C UniPathway UniProtKB {GO:0005737=GO_REF:0000039, GO:0016567=GO_REF:0000041} Q96JP0 Protein fem-1 homolog C protein 20130413 {GO:0005737=IEA, GO:0016567=IEA} protein ubiquitination cytoplasm Human UniPathway:UPA00143 FEN1 HPA UniProtKB {GO:0005515=PMID:18499658, GO:0009650=PMID:8007985, GO:0008409=PMID:7961795, GO:0005634=GO_REF:0000052, GO:0006302=PMID:8131753, GO:0005739=PMID:18995831, GO:0000084=Reactome:REACT_899, GO:0006271=Reactome:REACT_932, GO:0004527=PMID:9778254, GO:0003690=PMID:8131753, GO:0000723=Reactome:REACT_7970, GO:0004523=PMID:7961795, GO:0000722=Reactome:REACT_8027, GO:0048256=GO_REF:0000019, GO:0007613=GO_REF:0000019, GO:0008309=PMID:8131753, GO:0030145=GO_REF:0000019, GO:0000287=GO_REF:0000020, GO:0048015=PMID:15504738, GO:0005730=GO_REF:0000039, GO:0003677=PMID:11986308, GO:0006260=PMID:15504738, GO:0003684=PMID:8007985, GO:0004518=GO_REF:0000002, GO:0006281=Reactome:REACT_216, GO:0004519=PMID:8131753, GO:0006284=Reactome:REACT_1104, GO:0005654=Reactome:REACT_7975, GO:0017108=PMID:18995831, GO:0043137=PMID:18995831, GO:0000278=Reactome:REACT_152, GO:0032201=Reactome:REACT_7961} P39748 Flap endonuclease 1 protein 20080818 {GO:0005515=IPI, GO:0009650=TAS, GO:0008409=IDA, GO:0005634=IDA, GO:0006302=TAS, GO:0005739=IDA, GO:0000084=TAS, GO:0006271=TAS, GO:0004527=TAS, GO:0003690=TAS, GO:0000723=TAS, GO:0004523=IDA, GO:0000722=TAS, GO:0048256=IEA, GO:0007613=IEA, GO:0008309=TAS, GO:0030145=IEA, GO:0000287=IEA, GO:0048015=NAS, GO:0005730=IEA, GO:0003677=IMP, GO:0006260=NAS, GO:0003684=TAS, GO:0004518=IEA, GO:0006281=TAS, GO:0004519=TAS, GO:0006284=TAS, GO:0005654=TAS, GO:0017108=IDA, GO:0043137=IDA, GO:0000278=TAS, GO:0032201=TAS} DNA repair, DNA replication, DNA replication, removal of RNA primer, DNA strand elongation involved in DNA replication, S phase of mitotic cell cycle, UV protection, base-excision repair, double-strand break repair, memory, mitotic cell cycle, phosphatidylinositol-mediated signaling, telomere maintenance, telomere maintenance via recombination, telomere maintenance via semi-conservative replication mitochondrion, nucleolus, nucleoplasm, nucleus 5'-3' exonuclease activity, 5'-flap endonuclease activity, DNA binding, damaged DNA binding, double-stranded DNA binding, double-stranded DNA specific exodeoxyribonuclease activity, endonuclease activity, exonuclease activity, flap endonuclease activity, magnesium ion binding, manganese ion binding, nuclease activity, protein binding, ribonuclease H activity Human FER HPA UniProtKB {GO:0005154=PMID:21518868, GO:0000790=PMID:1990274, GO:0030054=PMID:12972546, GO:0042503=PMID:19147545, GO:0019221=PMID:9722593, GO:0050904=GO_REF:0000024, GO:0010762=GO_REF:0000019, GO:0046777=PMID:7623846, GO:0030838=PMID:19738202, GO:0006935=GO_REF:0000019, GO:0016301=GO_REF:0000038, GO:0032496=GO_REF:0000024, GO:0034446=GO_REF:0000024, GO:0070102=PMID:19147545, GO:0005938=GO_REF:0000039, GO:0017137=GO_REF:0000019, GO:0032869=GO_REF:0000024, GO:0036006=PMID:9722593, GO:0030335=PMID:19738202, GO:0045296=GO_REF:0000019, GO:0019901=GO_REF:0000019, GO:0045295=GO_REF:0000019, GO:0031532=GO_REF:0000024, GO:0018108=PMID:12972546, GO:0035426=GO_REF:0000024, GO:0038028=GO_REF:0000024, GO:0030027=PMID:19738202, GO:0042058=PMID:21518868, GO:0031234=PMID:19738202, GO:0044331=GO_REF:0000024, GO:0000278=PMID:22223638, GO:0038095=GO_REF:0000024, GO:0038109=GO_REF:0000024, GO:0008284=PMID:20111072, GO:0008283=PMID:22223638, GO:0033007=GO_REF:0000024, GO:0005634=PMID:19147545, GO:0015629=PMID:19738202, GO:0036119=GO_REF:0000024, GO:0005829=Reactome:REACT_111221, GO:0008289=PMID:19738202, GO:0010591=PMID:19738202, GO:0035556=PMID:2209086, GO:0005737=GO_REF:0000052, GO:0051092=PMID:21518868, GO:0015630=PMID:12972546, GO:0000226=PMID:12972546, GO:0003779=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0034614=GO_REF:0000024, GO:0006468=PMID:2725517, GO:0008157=GO_REF:0000019, GO:0001932=GO_REF:0000024, GO:0048008=GO_REF:0000024, GO:0004713=PMID:2725517, GO:0004715=PMID:12972546} P16591 Tyrosine-protein kinase Fer protein 20080205 {GO:0005154=IDA, GO:0000790=IDA, GO:0030054=IDA, GO:0042503=IDA, GO:0019221=IMP, GO:0050904=ISS, GO:0010762=IEA, GO:0046777=IDA, GO:0030838=IMP, GO:0006935=IEA, GO:0016301=IEA, GO:0032496=ISS, GO:0034446=ISS, GO:0070102=IMP, GO:0005938=IEA, GO:0017137=IEA, GO:0032869=ISS, GO:0036006=IMP, GO:0030335=IMP, GO:0045296=IEA, GO:0019901=IEA, GO:0045295=IEA, GO:0031532=ISS, GO:0018108=IDA, GO:0035426=ISS, GO:0038028=ISS, GO:0030027=IDA, GO:0042058=IMP, GO:0031234=IDA, GO:0044331=ISS, GO:0000278=IMP, GO:0038095=ISS, GO:0038109=ISS, GO:0008284=TAS, GO:0008283=IMP, GO:0033007=ISS, GO:0005634=IDA, GO:0015629=IDA, GO:0036119=ISS, GO:0005829=TAS, GO:0008289=IDA, GO:0010591=IDA, GO:0035556=TAS, GO:0005737=IDA, GO:0051092=IMP, GO:0015630=IDA, GO:0000226=IMP, GO:0003779=IEA, GO:0005524=IEA, GO:0034614=ISS, GO:0006468=TAS, GO:0008157=IEA, GO:0001932=ISS, GO:0048008=ISS, GO:0004713=TAS, GO:0004715=IDA} Fc-epsilon receptor signaling pathway, Kit signaling pathway, actin cytoskeleton reorganization, cell proliferation, cell-cell adhesion mediated by cadherin, cellular response to insulin stimulus, cellular response to macrophage colony-stimulating factor stimulus, cellular response to reactive oxygen species, chemotaxis, cytokine-mediated signaling pathway, diapedesis, extracellular matrix-cell signaling, insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade, interleukin-6-mediated signaling pathway, intracellular signal transduction, microtubule cytoskeleton organization, mitotic cell cycle, negative regulation of mast cell activation involved in immune response, peptidyl-tyrosine phosphorylation, platelet-derived growth factor receptor signaling pathway, positive regulation of NF-kappaB transcription factor activity, positive regulation of actin filament polymerization, positive regulation of cell migration, positive regulation of cell proliferation, protein autophosphorylation, protein phosphorylation, regulation of epidermal growth factor receptor signaling pathway, regulation of fibroblast migration, regulation of lamellipodium assembly, regulation of protein phosphorylation, response to lipopolysaccharide, response to platelet-derived growth factor stimulus, substrate adhesion-dependent cell spreading, tyrosine phosphorylation of Stat3 protein actin cytoskeleton, cell cortex, cell junction, cytoplasm, cytosol, extrinsic to internal side of plasma membrane, lamellipodium, microtubule cytoskeleton, nuclear chromatin, nucleus ATP binding, Rab GTPase binding, actin binding, cadherin binding, epidermal growth factor receptor binding, gamma-catenin binding, kinase activity, lipid binding, non-membrane spanning protein tyrosine kinase activity, protein kinase binding, protein phosphatase 1 binding, protein tyrosine kinase activity Human FER1L6 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q2WGJ9 Fer-1-like protein 6 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 FERD3L UniProtKB UniProtKB {GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000024, GO:0045892=GO_REF:0000024, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96RJ6 Fer3-like protein protein 20080326 {GO:0046983=IEA, GO:0005634=ISS, GO:0045892=ISS, GO:0003677=IEA, GO:0006351=IEA} negative regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, protein dimerization activity Human UniProtKB:Q923Z4 FERMT1 UniProtKB UniProtKB {GO:0090162=PMID:17012746, GO:0051546=PMID:17012746, GO:0030054=PMID:17012746, GO:0031941=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0032587=GO_REF:0000039, GO:0007155=PMID:17012746, GO:0043616=PMID:17012746, GO:0005925=GO_REF:0000039, GO:0005829=PMID:17012746} Q9BQL6 Fermitin family homolog 1 protein 20100122 {GO:0090162=IDA, GO:0051546=IDA, GO:0030054=IDA, GO:0031941=IEA, GO:0005543=IEA, GO:0032587=IEA, GO:0007155=IDA, GO:0043616=IDA, GO:0005925=IEA, GO:0005829=IDA} cell adhesion, establishment of epithelial cell polarity, keratinocyte migration, keratinocyte proliferation cell junction, cytosol, filamentous actin, focal adhesion, ruffle membrane phospholipid binding Human FERMT2 HPA UniProtKB {GO:0001725=GO_REF:0000019, GO:0030036=GO_REF:0000029, GO:0034329=Reactome:REACT_20676, GO:0008360=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005547=PMID:22030399, GO:0005634=GO_REF:0000052, GO:0072657=GO_REF:0000024, GO:0005829=Reactome:REACT_20555, GO:0033622=PMID:22030399, GO:0031234=PMID:21325030, GO:0005737=PMID:22699938, GO:0031941=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0007160=GO_REF:0000024, GO:0007229=PMID:21325030, GO:0048041=GO_REF:0000024, GO:0034446=GO_REF:0000024, GO:0007179=PMID:21325030, GO:0016055=PMID:22699938, GO:0005856=GO_REF:0000002, GO:0005925=GO_REF:0000052, GO:0005938=GO_REF:0000039} Q96AC1 Fermitin family homolog 2 protein 20110516 {GO:0001725=IEA, GO:0030036=NAS, GO:0034329=TAS, GO:0008360=IEA, GO:0005730=IDA, GO:0005547=IDA, GO:0005634=IDA, GO:0072657=ISS, GO:0005829=TAS, GO:0033622=IMP, GO:0031234=IDA, GO:0005737=IDA, GO:0031941=IEA, GO:0005543=IEA, GO:0007160=ISS, GO:0007229=IMP, GO:0048041=ISS, GO:0034446=ISS, GO:0007179=IMP, GO:0016055=IMP, GO:0005856=IEA, GO:0005925=IDA, GO:0005938=IEA} Wnt receptor signaling pathway, actin cytoskeleton organization, cell junction assembly, cell-matrix adhesion, focal adhesion assembly, integrin activation, integrin-mediated signaling pathway, protein localization to membrane, regulation of cell shape, substrate adhesion-dependent cell spreading, transforming growth factor beta receptor signaling pathway cell cortex, cytoplasm, cytoskeleton, cytosol, extrinsic to internal side of plasma membrane, filamentous actin, focal adhesion, nucleolus, nucleus, stress fiber phosphatidylinositol-3,4,5-trisphosphate binding, phospholipid binding Human FERMT3 UniProtKB UniProtKB {GO:0070527=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0005543=GO_REF:0000002, GO:0005178=GO_REF:0000024, GO:0007159=PMID:19234460, GO:0002102=GO_REF:0000024, GO:0033632=PMID:19234463, GO:0042995=GO_REF:0000037, GO:0033622=PMID:19234463} Q86UX7 Fermitin family homolog 3 protein 20091113 {GO:0070527=ISS, GO:0030054=IEA, GO:0005543=IEA, GO:0005178=ISS, GO:0007159=IMP, GO:0002102=ISS, GO:0033632=IMP, GO:0042995=IEA, GO:0033622=IMP} integrin activation, leukocyte cell-cell adhesion, platelet aggregation, regulation of cell-cell adhesion mediated by integrin cell junction, cell projection, podosome integrin binding, phospholipid binding Human FES Reactome UniProtKB {GO:0008283=PMID:6264598, GO:0008360=PMID:18046454, GO:2000145=PMID:18046454, GO:2000251=PMID:15302586, GO:0030155=PMID:11509660, GO:0005829=Reactome:REACT_111221, GO:0005737=PMID:11339827, GO:0046777=PMID:7687763, GO:0045639=PMID:2656706, GO:0007411=Reactome:REACT_18266, GO:0042127=PMID:11509660, GO:0015630=PMID:15485904, GO:0060627=PMID:11339827, GO:0034987=PMID:19001085, GO:0043304=PMID:19001085, GO:0031116=PMID:15485904, GO:0005794=GO_REF:0000039, GO:0007275=PMID:6264598, GO:0018108=PMID:11509660, GO:0031410=PMID:11339827, GO:0005524=GO_REF:0000037, GO:0031234=PMID:18046454, GO:0004672=GO_REF:0000019, GO:0010976=PMID:15302586, GO:0016023=GO_REF:0000039, GO:0006468=PMID:6183005, GO:0045595=PMID:15302586, GO:0004713=PMID:11509660, GO:0035091=PMID:19001085, GO:0004715=PMID:15485904, GO:0005925=PMID:18046454} P07332 Tyrosine-protein kinase Fes/Fps protein 20090515 {GO:0008283=TAS, GO:0008360=IMP, GO:2000145=IMP, GO:2000251=IMP, GO:0030155=IMP, GO:0005829=TAS, GO:0005737=IDA, GO:0046777=IDA, GO:0045639=IMP, GO:0007411=TAS, GO:0042127=IMP, GO:0015630=IDA, GO:0060627=TAS, GO:0034987=IDA, GO:0043304=IMP, GO:0031116=IMP, GO:0005794=IEA, GO:0007275=TAS, GO:0018108=IDA, GO:0031410=IDA, GO:0005524=IEA, GO:0031234=IDA, GO:0004672=IEA, GO:0010976=IMP, GO:0016023=IEA, GO:0006468=TAS, GO:0045595=IMP, GO:0004713=IDA, GO:0035091=IDA, GO:0004715=IDA, GO:0005925=IDA} axon guidance, cell proliferation, multicellular organismal development, peptidyl-tyrosine phosphorylation, positive regulation of actin cytoskeleton reorganization, positive regulation of microtubule polymerization, positive regulation of myeloid cell differentiation, positive regulation of neuron projection development, protein autophosphorylation, protein phosphorylation, regulation of cell adhesion, regulation of cell differentiation, regulation of cell motility, regulation of cell proliferation, regulation of cell shape, regulation of mast cell degranulation, regulation of vesicle-mediated transport Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, cytoplasmic vesicle, cytosol, extrinsic to internal side of plasma membrane, focal adhesion, microtubule cytoskeleton ATP binding, immunoglobulin receptor binding, non-membrane spanning protein tyrosine kinase activity, phosphatidylinositol binding, protein kinase activity, protein tyrosine kinase activity Human FETUB UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0004869=GO_REF:0000002, GO:0005576=GO_REF:0000029, GO:0005615=GO_REF:0000002} Q9UGM5 Fetuin-B protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0004869=IEA, GO:0005576=NAS, GO:0005615=IEA} biological_process extracellular region, extracellular space cysteine-type endopeptidase inhibitor activity, molecular_function Human FEZ1 HPA UniProtKB {GO:0005515=PMID:16169070, GO:0030424=GO_REF:0000019, GO:0005813=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0043015=GO_REF:0000019, GO:0005874=GO_REF:0000037, GO:0030425=GO_REF:0000019, GO:0007399=PMID:9096408, GO:0051654=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0047485=GO_REF:0000019, GO:0071363=GO_REF:0000019, GO:0007411=PMID:9096408, GO:0045666=GO_REF:0000019, GO:0010976=GO_REF:0000019, GO:0015630=GO_REF:0000052, GO:0005080=GO_REF:0000019, GO:0006810=GO_REF:0000037, GO:0007155=PMID:9096408} Q99689 Fasciculation and elongation protein zeta-1 protein 20111111 {GO:0005515=IPI, GO:0030424=IEA, GO:0005813=IEA, GO:0005886=IEA, GO:0043015=IEA, GO:0005874=IEA, GO:0030425=IEA, GO:0007399=TAS, GO:0051654=IEA, GO:0005737=IDA, GO:0047485=IEA, GO:0071363=IEA, GO:0007411=TAS, GO:0045666=IEA, GO:0010976=IEA, GO:0015630=IDA, GO:0005080=IEA, GO:0006810=IEA, GO:0007155=TAS} axon guidance, cell adhesion, cellular response to growth factor stimulus, establishment of mitochondrion localization, nervous system development, positive regulation of neuron differentiation, positive regulation of neuron projection development, transport axon, centrosome, cytoplasm, dendrite, microtubule, microtubule cytoskeleton, plasma membrane gamma-tubulin binding, protein N-terminus binding, protein binding, protein kinase C binding Human FEZ2 IntAct UniProtKB {GO:0005515=PMID:14690447, GO:0007165=PMID:9096408, GO:0007411=PMID:9096408, GO:0007399=PMID:9096408} Q9UHY8 Fasciculation and elongation protein zeta-2 protein 20130415 {GO:0005515=IPI, GO:0007165=TAS, GO:0007411=TAS, GO:0007399=TAS} axon guidance, nervous system development, signal transduction protein binding Human UniProtKB:Q96PY6 FEZF1 ENSEMBL UniProtKB {GO:0008285=GO_REF:0000019, GO:0021772=GO_REF:0000019, GO:0045666=GO_REF:0000019, GO:0021797=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0000122=GO_REF:0000019, GO:0045893=GO_REF:0000019, GO:0001764=GO_REF:0000019, GO:0000978=GO_REF:0000019, GO:0006351=GO_REF:0000037} C9J0C5 Fez family zinc finger protein 1 protein 20130413 {GO:0008285=IEA, GO:0021772=IEA, GO:0045666=IEA, GO:0021797=IEA, GO:0007411=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0000122=IEA, GO:0045893=IEA, GO:0001764=IEA, GO:0000978=IEA, GO:0006351=IEA} axon guidance, forebrain anterior/posterior pattern specification, negative regulation of cell proliferation, negative regulation of transcription from RNA polymerase II promoter, neuron migration, olfactory bulb development, positive regulation of neuron differentiation, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding, zinc ion binding Human Ensembl:ENSMUSP00000031709 FFAR1 Reactome UniProtKB {GO:0005085=Reactome:REACT_19346, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0005886=Reactome:REACT_22436, GO:0007186=PMID:9344866, GO:0005887=PMID:9344866, GO:0004930=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0042593=GO_REF:0000019, GO:0030073=GO_REF:0000019, GO:0008289=GO_REF:0000037} O14842 Free fatty acid receptor 1 protein 20130213 {GO:0005085=TAS, GO:0006112=TAS, GO:0050796=TAS, GO:0005886=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0004930=IEA, GO:0044281=TAS, GO:0042593=IEA, GO:0030073=IEA, GO:0008289=IEA} G-protein coupled receptor signaling pathway, energy reserve metabolic process, glucose homeostasis, insulin secretion, regulation of insulin secretion, small molecule metabolic process integral to plasma membrane, plasma membrane G-protein coupled receptor activity, guanyl-nucleotide exchange factor activity, lipid binding Human FFAR2 Reactome UniProtKB {GO:0005886=Reactome:REACT_22436, GO:0007186=PMID:9344866, GO:0005887=PMID:9344866, GO:0004930=GO_REF:0000037, GO:0008289=GO_REF:0000037} O15552 Free fatty acid receptor 2 protein 20091021 {GO:0005886=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0004930=IEA, GO:0008289=IEA} G-protein coupled receptor signaling pathway integral to plasma membrane, plasma membrane G-protein coupled receptor activity, lipid binding Human FFAR3 Reactome UniProtKB {GO:0005886=Reactome:REACT_22436, GO:0007186=PMID:9344866, GO:0005887=PMID:9344866, GO:0004930=GO_REF:0000037, GO:0008289=GO_REF:0000037} O14843 Free fatty acid receptor 3 protein 20091021 {GO:0005886=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0004930=IEA, GO:0008289=IEA} G-protein coupled receptor signaling pathway integral to plasma membrane, plasma membrane G-protein coupled receptor activity, lipid binding Human FGA BHF-UCL UniProtKB {GO:0005515=PMID:10954706, GO:0051258=GO_REF:0000002, GO:0043499=PMID:6777381, GO:0005886=Reactome:REACT_726, GO:0005102=GO_REF:0000002, GO:0005577=GO_REF:0000002, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_75905, GO:0005615=PMID:6777381, GO:0051592=PMID:6777381, GO:0007165=GO_REF:0000002, GO:0007596=Reactome:REACT_2051, GO:0002576=Reactome:REACT_318, GO:0031091=PMID:6777381, GO:0031093=Reactome:REACT_21351, GO:0030674=GO_REF:0000002, GO:0005938=GO_REF:0000019, GO:0009897=PMID:6777381} P02671 Fibrinogen alpha chain protein 20081001 {GO:0005515=IPI, GO:0051258=IEA, GO:0043499=IDA, GO:0005886=TAS, GO:0005102=IEA, GO:0005577=IEA, GO:0030168=TAS, GO:0005576=TAS, GO:0005615=IDA, GO:0051592=IDA, GO:0007165=IEA, GO:0007596=TAS, GO:0002576=TAS, GO:0031091=IDA, GO:0031093=TAS, GO:0030674=IEA, GO:0005938=IEA, GO:0009897=IDA} blood coagulation, platelet activation, platelet degranulation, protein polymerization, response to calcium ion, signal transduction cell cortex, external side of plasma membrane, extracellular region, extracellular space, fibrinogen complex, plasma membrane, platelet alpha granule, platelet alpha granule lumen eukaryotic cell surface binding, protein binding, protein binding, bridging, receptor binding Human FGB BHF-UCL UniProtKB {GO:0051258=GO_REF:0000002, GO:0043499=PMID:6777381, GO:0005886=Reactome:REACT_726, GO:0051087=PMID:19996109, GO:0005102=GO_REF:0000002, GO:0005577=GO_REF:0000002, GO:0030168=Reactome:REACT_798, GO:0072562=GO_REF:0000019, GO:0005576=Reactome:REACT_23931, GO:0005615=PMID:6777381, GO:0051592=PMID:6777381, GO:0007165=GO_REF:0000002, GO:0007596=Reactome:REACT_2051, GO:0002576=Reactome:REACT_318, GO:0031091=PMID:6777381, GO:0031093=Reactome:REACT_21351, GO:0030674=GO_REF:0000002, GO:0005938=GO_REF:0000019, GO:0009897=PMID:6777381} P02675 Fibrinogen beta chain protein 20081001 {GO:0051258=IEA, GO:0043499=IDA, GO:0005886=TAS, GO:0051087=IPI, GO:0005102=IEA, GO:0005577=IEA, GO:0030168=TAS, GO:0072562=IEA, GO:0005576=TAS, GO:0005615=IDA, GO:0051592=IDA, GO:0007165=IEA, GO:0007596=TAS, GO:0002576=TAS, GO:0031091=IDA, GO:0031093=TAS, GO:0030674=IEA, GO:0005938=IEA, GO:0009897=IDA} blood coagulation, platelet activation, platelet degranulation, protein polymerization, response to calcium ion, signal transduction blood microparticle, cell cortex, external side of plasma membrane, extracellular region, extracellular space, fibrinogen complex, plasma membrane, platelet alpha granule, platelet alpha granule lumen chaperone binding, eukaryotic cell surface binding, protein binding, bridging, receptor binding Human FGD1 HPA UniProtKB {GO:0030036=PMID:8969170, GO:0005886=GO_REF:0000052, GO:0031267=PMID:8969170, GO:0007264=Reactome:REACT_11044, GO:0008360=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_19216, GO:0005085=PMID:8969170, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0007010=GO_REF:0000024, GO:0009887=PMID:7954831, GO:0046847=PMID:8969170, GO:0005856=GO_REF:0000039, GO:0005089=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0005794=GO_REF:0000024, GO:0006915=Reactome:REACT_13638, GO:0007275=PMID:8969170, GO:0001726=GO_REF:0000024, GO:0097190=Reactome:REACT_13720, GO:0030027=GO_REF:0000024, GO:0043088=PMID:8969170, GO:0007165=PMID:8969170} P98174 FYVE, RhoGEF and PH domain-containing protein 1 protein 20100326 {GO:0030036=IDA, GO:0005886=IDA, GO:0031267=IDA, GO:0007264=TAS, GO:0008360=ISS, GO:0005634=IDA, GO:0046872=IEA, GO:0005829=TAS, GO:0005085=IDA, GO:0005737=IDA, GO:0005543=IEA, GO:0007010=ISS, GO:0009887=TAS, GO:0046847=IDA, GO:0005856=IEA, GO:0005089=IEA, GO:0051056=TAS, GO:0048011=TAS, GO:0005794=ISS, GO:0006915=TAS, GO:0007275=TAS, GO:0001726=ISS, GO:0097190=TAS, GO:0030027=ISS, GO:0043088=IDA, GO:0007165=TAS} actin cytoskeleton organization, apoptotic process, apoptotic signaling pathway, cytoskeleton organization, filopodium assembly, multicellular organismal development, neurotrophin TRK receptor signaling pathway, organ morphogenesis, regulation of Cdc42 GTPase activity, regulation of cell shape, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction Golgi apparatus, cytoplasm, cytoskeleton, cytosol, lamellipodium, nucleus, plasma membrane, ruffle Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, metal ion binding, phospholipid binding, small GTPase binding Human FGD2 Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0005794=GO_REF:0000024, GO:0030036=GO_REF:0000024, GO:0031267=GO_REF:0000024, GO:0007264=Reactome:REACT_11044, GO:0008360=GO_REF:0000024, GO:0006915=Reactome:REACT_13638, GO:0005634=GO_REF:0000039, GO:0032587=GO_REF:0000039, GO:0097190=Reactome:REACT_13720, GO:0001726=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0030027=GO_REF:0000024, GO:0005829=Reactome:REACT_19216, GO:0043088=GO_REF:0000024, GO:0005085=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0005543=GO_REF:0000002, GO:0031901=GO_REF:0000039, GO:0007010=GO_REF:0000024, GO:0046847=GO_REF:0000024, GO:0005089=GO_REF:0000002, GO:0005856=GO_REF:0000039} Q7Z6J4 FYVE, RhoGEF and PH domain-containing protein 2 protein 20130301 {GO:0051056=TAS, GO:0048011=TAS, GO:0005794=ISS, GO:0030036=ISS, GO:0031267=ISS, GO:0007264=TAS, GO:0008360=ISS, GO:0006915=TAS, GO:0005634=IEA, GO:0032587=IEA, GO:0097190=TAS, GO:0001726=ISS, GO:0046872=IEA, GO:0030027=ISS, GO:0005829=TAS, GO:0043088=ISS, GO:0005085=ISS, GO:0005737=ISS, GO:0005543=IEA, GO:0031901=IEA, GO:0007010=ISS, GO:0046847=ISS, GO:0005089=IEA, GO:0005856=IEA} actin cytoskeleton organization, apoptotic process, apoptotic signaling pathway, cytoskeleton organization, filopodium assembly, neurotrophin TRK receptor signaling pathway, regulation of Cdc42 GTPase activity, regulation of cell shape, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction Golgi apparatus, cytoplasm, cytoskeleton, cytosol, early endosome membrane, lamellipodium, nucleus, ruffle, ruffle membrane Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, metal ion binding, phospholipid binding, small GTPase binding Human FGD3 Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0005794=GO_REF:0000024, GO:0030036=GO_REF:0000024, GO:0031267=GO_REF:0000024, GO:0007264=Reactome:REACT_11044, GO:0035023=GO_REF:0000002, GO:0008360=GO_REF:0000024, GO:0006915=Reactome:REACT_13638, GO:0097190=Reactome:REACT_13720, GO:0001726=GO_REF:0000024, GO:0030027=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_19216, GO:0043088=GO_REF:0000024, GO:0005622=GO_REF:0000002, GO:0005085=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0005543=GO_REF:0000002, GO:0007010=GO_REF:0000024, GO:0046847=GO_REF:0000024, GO:0005089=GO_REF:0000002, GO:0005856=GO_REF:0000039} Q5JSP0 FYVE, RhoGEF and PH domain-containing protein 3 protein 20130301 {GO:0051056=TAS, GO:0048011=TAS, GO:0005794=ISS, GO:0030036=ISS, GO:0031267=ISS, GO:0007264=TAS, GO:0035023=IEA, GO:0008360=ISS, GO:0006915=TAS, GO:0097190=TAS, GO:0001726=ISS, GO:0030027=ISS, GO:0046872=IEA, GO:0005829=TAS, GO:0043088=ISS, GO:0005622=IEA, GO:0005085=ISS, GO:0005737=ISS, GO:0005543=IEA, GO:0007010=ISS, GO:0046847=ISS, GO:0005089=IEA, GO:0005856=IEA} actin cytoskeleton organization, apoptotic process, apoptotic signaling pathway, cytoskeleton organization, filopodium assembly, neurotrophin TRK receptor signaling pathway, regulation of Cdc42 GTPase activity, regulation of Rho protein signal transduction, regulation of cell shape, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction Golgi apparatus, cytoplasm, cytoskeleton, cytosol, intracellular, lamellipodium, ruffle Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, metal ion binding, phospholipid binding, small GTPase binding Human FGD4 HPA UniProtKB {GO:0030036=GO_REF:0000024, GO:0030035=GO_REF:0000019, GO:0031267=GO_REF:0000024, GO:0035023=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0008360=GO_REF:0000024, GO:0030032=GO_REF:0000019, GO:0030175=GO_REF:0000039, GO:0015629=GO_REF:0000052, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_19216, GO:0005622=GO_REF:0000002, GO:0005085=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0005543=GO_REF:0000002, GO:0007010=GO_REF:0000024, GO:0046847=GO_REF:0000024, GO:0005089=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0005794=GO_REF:0000024, GO:0006915=Reactome:REACT_13638, GO:0003779=GO_REF:0000037, GO:0097190=Reactome:REACT_13720, GO:0001726=GO_REF:0000024, GO:0030027=GO_REF:0000024, GO:0043088=GO_REF:0000024} Q96M96 FYVE, RhoGEF and PH domain-containing protein 4 protein 20110516 {GO:0030036=ISS, GO:0030035=IEA, GO:0031267=ISS, GO:0035023=IEA, GO:0007264=TAS, GO:0008360=ISS, GO:0030032=IEA, GO:0030175=IEA, GO:0015629=IDA, GO:0046872=IEA, GO:0005829=TAS, GO:0005622=IEA, GO:0005085=ISS, GO:0005737=ISS, GO:0005543=IEA, GO:0007010=ISS, GO:0046847=ISS, GO:0005089=IEA, GO:0051056=TAS, GO:0048011=TAS, GO:0005794=ISS, GO:0006915=TAS, GO:0003779=IEA, GO:0097190=TAS, GO:0001726=ISS, GO:0030027=ISS, GO:0043088=ISS} actin cytoskeleton organization, apoptotic process, apoptotic signaling pathway, cytoskeleton organization, filopodium assembly, lamellipodium assembly, microspike assembly, neurotrophin TRK receptor signaling pathway, regulation of Cdc42 GTPase activity, regulation of Rho protein signal transduction, regulation of cell shape, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction Golgi apparatus, actin cytoskeleton, cytoplasm, cytosol, filopodium, intracellular, lamellipodium, ruffle Rho guanyl-nucleotide exchange factor activity, actin binding, guanyl-nucleotide exchange factor activity, metal ion binding, phospholipid binding, small GTPase binding Human FGD5 UniProtKB UniProtKB {GO:0005794=GO_REF:0000024, GO:0030036=GO_REF:0000024, GO:0031267=GO_REF:0000024, GO:0035023=GO_REF:0000002, GO:0005783=GO_REF:0000039, GO:0008360=GO_REF:0000024, GO:0032587=GO_REF:0000039, GO:0001726=GO_REF:0000024, GO:0030027=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0043088=GO_REF:0000024, GO:0005622=GO_REF:0000002, GO:0005085=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0005543=GO_REF:0000002, GO:0007010=GO_REF:0000024, GO:0046847=GO_REF:0000024, GO:0005089=GO_REF:0000002, GO:0005856=GO_REF:0000039, GO:0005769=GO_REF:0000039} Q6ZNL6 FYVE, RhoGEF and PH domain-containing protein 5 protein 20050412 {GO:0005794=ISS, GO:0030036=ISS, GO:0031267=ISS, GO:0035023=IEA, GO:0005783=IEA, GO:0008360=ISS, GO:0032587=IEA, GO:0001726=ISS, GO:0030027=ISS, GO:0046872=IEA, GO:0043088=ISS, GO:0005622=IEA, GO:0005085=ISS, GO:0005737=ISS, GO:0005543=IEA, GO:0007010=ISS, GO:0046847=ISS, GO:0005089=IEA, GO:0005856=IEA, GO:0005769=IEA} actin cytoskeleton organization, cytoskeleton organization, filopodium assembly, regulation of Cdc42 GTPase activity, regulation of Rho protein signal transduction, regulation of cell shape Golgi apparatus, cytoplasm, cytoskeleton, early endosome, endoplasmic reticulum, intracellular, lamellipodium, ruffle, ruffle membrane Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, metal ion binding, phospholipid binding, small GTPase binding Human UniProtKB:P52734 FGD6 UniProtKB UniProtKB {GO:0005794=GO_REF:0000024, GO:0030036=GO_REF:0000024, GO:0031267=GO_REF:0000024, GO:0035023=GO_REF:0000002, GO:0008360=GO_REF:0000024, GO:0001726=GO_REF:0000024, GO:0030027=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0043088=GO_REF:0000024, GO:0005622=GO_REF:0000002, GO:0005085=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0005543=GO_REF:0000002, GO:0007010=GO_REF:0000024, GO:0046847=GO_REF:0000024, GO:0005089=GO_REF:0000002, GO:0005856=GO_REF:0000039} Q6ZV73 FYVE, RhoGEF and PH domain-containing protein 6 protein 20050412 {GO:0005794=ISS, GO:0030036=ISS, GO:0031267=ISS, GO:0035023=IEA, GO:0008360=ISS, GO:0001726=ISS, GO:0030027=ISS, GO:0046872=IEA, GO:0043088=ISS, GO:0005622=IEA, GO:0005085=ISS, GO:0005737=ISS, GO:0005543=IEA, GO:0007010=ISS, GO:0046847=ISS, GO:0005089=IEA, GO:0005856=IEA} actin cytoskeleton organization, cytoskeleton organization, filopodium assembly, regulation of Cdc42 GTPase activity, regulation of Rho protein signal transduction, regulation of cell shape Golgi apparatus, cytoplasm, cytoskeleton, intracellular, lamellipodium, ruffle Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, metal ion binding, phospholipid binding, small GTPase binding Human UniProtKB:P52734 FGF1 BHF-UCL UniProtKB {GO:0005515=PMID:18441324, GO:0008286=Reactome:REACT_498, GO:0008284=PMID:18187602, GO:0030324=GO_REF:0000019, GO:0001759=GO_REF:0000019, GO:0009653=PMID:1693186, GO:0005615=PMID:18400376, GO:0005829=PMID:12746488, GO:0034605=PMID:12746488, GO:0005737=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0045944=PMID:19229075, GO:0051781=PMID:20145243, GO:0005938=GO_REF:0000039, GO:0008201=PMID:20145243, GO:0050679=GO_REF:0000019, GO:0010740=PMID:19229075, GO:0048011=Reactome:REACT_11061, GO:0030335=PMID:20145243, GO:0060681=PMID:11731227, GO:0048015=Reactome:REACT_12464, GO:0005730=GO_REF:0000019, GO:0005578=GO_REF:0000019, GO:0007275=PMID:10903182, GO:0005576=Reactome:REACT_147854, GO:0005104=PMID:12815063, GO:0001525=GO_REF:0000037, GO:0045766=PMID:20145243, GO:0044548=PMID:11432880, GO:0007165=PMID:3778488, GO:0008543=Reactome:REACT_9515, GO:0045087=Reactome:REACT_6802, GO:0001934=GO_REF:0000019, GO:0030544=GO_REF:0000019, GO:0072163=PMID:11731227, GO:0008083=PMID:20145243, GO:0045542=PMID:19229075} P05230 Fibroblast growth factor 1 protein 20101229 {GO:0005515=IPI, GO:0008286=TAS, GO:0008284=IGI, GO:0030324=IEA, GO:0001759=IEA, GO:0009653=TAS, GO:0005615=IDA, GO:0005829=IDA, GO:0034605=IDA, GO:0005737=IEA, GO:0007173=TAS, GO:0045944=IDA, GO:0051781=IDA, GO:0005938=IEA, GO:0008201=IDA, GO:0050679=IEA, GO:0010740=IDA, GO:0048011=TAS, GO:0030335=IDA, GO:0060681=IDA, GO:0048015=TAS, GO:0005730=IEA, GO:0005578=IEA, GO:0007275=TAS, GO:0005576=TAS, GO:0005104=IPI, GO:0001525=IEA, GO:0045766=IDA, GO:0044548=IPI, GO:0007165=NAS, GO:0008543=TAS, GO:0045087=TAS, GO:0001934=IEA, GO:0030544=IEA, GO:0072163=IDA, GO:0008083=IDA, GO:0045542=IDA} anatomical structure morphogenesis, angiogenesis, branch elongation involved in ureteric bud branching, cellular response to heat, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, lung development, mesonephric epithelium development, multicellular organismal development, neurotrophin TRK receptor signaling pathway, organ induction, phosphatidylinositol-mediated signaling, positive regulation of angiogenesis, positive regulation of cell division, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of cholesterol biosynthetic process, positive regulation of epithelial cell proliferation, positive regulation of intracellular protein kinase cascade, positive regulation of protein phosphorylation, positive regulation of transcription from RNA polymerase II promoter, signal transduction cell cortex, cytoplasm, cytosol, extracellular region, extracellular space, nucleolus, proteinaceous extracellular matrix Hsp70 protein binding, S100 protein binding, fibroblast growth factor receptor binding, growth factor activity, heparin binding, protein binding Human FGF10 Reactome UniProtKB {GO:0010838=PMID:17449030, GO:0051549=PMID:17449030, GO:0090263=GO_REF:0000019, GO:0005111=PMID:19224135, GO:0050731=PMID:17449030, GO:0046579=PMID:12804770, GO:0030878=GO_REF:0000019, GO:0005615=PMID:16597614, GO:0031069=GO_REF:0000019, GO:0060430=PMID:17071719, GO:0031076=GO_REF:0000019, GO:0060915=GO_REF:0000019, GO:0060436=GO_REF:0000019, GO:0045747=GO_REF:0000019, GO:0031532=PMID:17449030, GO:0009986=PMID:11923311, GO:0045740=PMID:17471512, GO:0042056=PMID:9740653, GO:0050930=GO_REF:0000019, GO:0046877=PMID:19102732, GO:0060441=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0042060=PMID:11896977, GO:0060447=PMID:9740653, GO:0051145=GO_REF:0000019, GO:0060595=PMID:11923311, GO:0021983=GO_REF:0000019, GO:0005634=PMID:17471512, GO:0048146=GO_REF:0000019, GO:0045739=PMID:14975937, GO:0000187=PMID:14975937, GO:0060665=GO_REF:0000019, GO:0060664=GO_REF:0000019, GO:0060667=GO_REF:0000019, GO:0060661=GO_REF:0000019, GO:0042475=GO_REF:0000019, GO:0007431=PMID:17213838, GO:0035019=GO_REF:0000019, GO:0060054=PMID:19152659, GO:0048011=Reactome:REACT_11061, GO:0048015=Reactome:REACT_12464, GO:0001823=PMID:18437684, GO:0005576=Reactome:REACT_147854, GO:0005104=PMID:11923311, GO:0050918=PMID:9740653, GO:0032808=PMID:17213838, GO:0003338=GO_REF:0000019, GO:0048557=GO_REF:0000019, GO:0001974=GO_REF:0000019, GO:0034394=PMID:17449030, GO:0060510=GO_REF:0000019, GO:0048754=PMID:17959718, GO:0061033=PMID:10541313, GO:0001656=PMID:18437684, GO:0071157=PMID:17188682, GO:0048538=PMID:17969154, GO:0001759=GO_REF:0000019, GO:0048536=GO_REF:0000019, GO:0042693=GO_REF:0000019, GO:0009880=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0030538=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0048808=GO_REF:0000019, GO:0048807=GO_REF:0000019, GO:0070374=PMID:14975937, GO:0070371=PMID:17959718, GO:0032355=GO_REF:0000019, GO:0050679=GO_REF:0000019, GO:0060685=GO_REF:0000019, GO:0050677=PMID:11923311, GO:0048286=GO_REF:0000019, GO:0061115=GO_REF:0000019, GO:0030916=GO_REF:0000019, GO:0050671=PMID:19152659, GO:0032781=PMID:12804770, GO:0032925=GO_REF:0000019, GO:0050674=PMID:11923311, GO:0050673=PMID:19224135, GO:0045931=GO_REF:0000019, GO:0050872=GO_REF:0000019, GO:0008543=Reactome:REACT_9483, GO:0070384=GO_REF:0000019, GO:0060174=GO_REF:0000019, GO:0045893=PMID:17500053, GO:0008083=PMID:15690149, GO:0008286=Reactome:REACT_498, GO:0030949=GO_REF:0000019, GO:0007368=GO_REF:0000019, GO:0060428=PMID:9740653, GO:0008285=GO_REF:0000019, GO:0005886=PMID:16597614, GO:0060879=GO_REF:0000019, GO:0042246=GO_REF:0000019, GO:0035265=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0071338=PMID:16086254, GO:0060496=GO_REF:0000019, GO:0008201=PMID:11923311, GO:0070352=GO_REF:0000019, GO:0070075=PMID:19102732, GO:0043066=GO_REF:0000019, GO:0001525=GO_REF:0000019, GO:0043616=GO_REF:0000019, GO:0031012=PMID:17959718, GO:0031659=PMID:17188682, GO:0031016=GO_REF:0000019, GO:0060019=GO_REF:0000024, GO:0008589=GO_REF:0000019, GO:0060615=GO_REF:0000019, GO:0010631=GO_REF:0000019, GO:0010634=PMID:17500053, GO:0043410=PMID:12804770} O15520 Fibroblast growth factor 10 protein 20130301 {GO:0010838=IDA, GO:0051549=IDA, GO:0090263=IEA, GO:0005111=IPI, GO:0050731=IDA, GO:0046579=IDA, GO:0030878=IEA, GO:0005615=IDA, GO:0031069=IEA, GO:0060430=IMP, GO:0031076=IEA, GO:0060915=IEA, GO:0060436=IEA, GO:0045747=IEA, GO:0031532=IDA, GO:0009986=NAS, GO:0045740=IMP, GO:0042056=IDA, GO:0050930=IEA, GO:0046877=IMP, GO:0060441=IEA, GO:0045087=TAS, GO:0042060=IDA, GO:0060447=IDA, GO:0051145=IEA, GO:0060595=IDA, GO:0021983=IEA, GO:0005634=IDA, GO:0048146=IEA, GO:0045739=IDA, GO:0000187=IDA, GO:0060665=IEA, GO:0060664=IEA, GO:0060667=IEA, GO:0060661=IEA, GO:0042475=IEA, GO:0007431=IMP, GO:0035019=IEA, GO:0060054=NAS, GO:0048011=TAS, GO:0048015=TAS, GO:0001823=IEP, GO:0005576=TAS, GO:0005104=IDA, GO:0050918=IDA, GO:0032808=IMP, GO:0003338=IEA, GO:0048557=IEA, GO:0001974=IEA, GO:0034394=IDA, GO:0060510=IEA, GO:0048754=IDA, GO:0061033=IDA, GO:0001656=IEP, GO:0071157=IDA, GO:0048538=IDA, GO:0001759=IEA, GO:0048536=IEA, GO:0042693=IEA, GO:0009880=IEA, GO:0007173=TAS, GO:0030538=IEA, GO:0032496=IEA, GO:0048808=IEA, GO:0048807=IEA, GO:0070374=IDA, GO:0070371=IDA, GO:0032355=IEA, GO:0050679=IEA, GO:0060685=IEA, GO:0050677=IDA, GO:0048286=IEA, GO:0061115=IEA, GO:0030916=IEA, GO:0050671=IDA, GO:0032781=IDA, GO:0032925=IEA, GO:0050674=IDA, GO:0050673=IDA, GO:0045931=IEA, GO:0050872=IEA, GO:0008543=TAS, GO:0070384=IEA, GO:0060174=IEA, GO:0045893=IDA, GO:0008083=IDA, GO:0008286=TAS, GO:0030949=IEA, GO:0007368=IEA, GO:0060428=IDA, GO:0008285=IEA, GO:0005886=IDA, GO:0060879=IEA, GO:0042246=IEA, GO:0035265=IEA, GO:0045944=IEA, GO:0071338=IDA, GO:0060496=IEA, GO:0008201=IDA, GO:0070352=IEA, GO:0070075=IMP, GO:0043066=IEA, GO:0001525=IEA, GO:0043616=IEA, GO:0031012=IDA, GO:0031659=IDA, GO:0031016=IEA, GO:0060019=ISS, GO:0008589=IEA, GO:0060615=IEA, GO:0010631=IEA, GO:0010634=IDA, GO:0043410=IDA} ERK1 and ERK2 cascade, Harderian gland development, Type II pneumocyte differentiation, actin cytoskeleton reorganization, activation of MAPK activity, angiogenesis, blood vessel remodeling, branch elongation involved in salivary gland morphogenesis, branching morphogenesis of an epithelial tube, bronchiole morphogenesis, bud outgrowth involved in lung branching, determination of left/right symmetry, embryonic camera-type eye development, embryonic digestive tract morphogenesis, embryonic genitalia morphogenesis, embryonic pattern specification, epidermal growth factor receptor signaling pathway, epithelial cell migration, epithelial cell proliferation, epithelial cell proliferation involved in salivary gland morphogenesis, epithelial tube branching involved in lung morphogenesis, female genitalia morphogenesis, fibroblast growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway involved in mammary gland specification, hair follicle morphogenesis, induction of positive chemotaxis, innate immune response, insulin receptor signaling pathway, keratinocyte proliferation, lacrimal gland development, limb bud formation, lung alveolus development, lung epithelium development, lung proximal/distal axis specification, lung saccule development, male genitalia morphogenesis, mammary gland bud formation, mesenchymal cell differentiation involved in lung development, mesenchymal-epithelial cell signaling involved in lung development, mesonephros development, metanephros development, metanephros morphogenesis, muscle cell fate commitment, negative regulation of apoptotic process, negative regulation of cell cycle arrest, negative regulation of cell proliferation, neurotrophin TRK receptor signaling pathway, odontogenesis of dentin-containing tooth, organ growth, organ induction, otic vesicle formation, pancreas development, phosphatidylinositol-mediated signaling, pituitary gland development, positive chemotaxis, positive regulation of ATPase activity, positive regulation of DNA repair, positive regulation of DNA replication, positive regulation of ERK1 and ERK2 cascade, positive regulation of MAPK cascade, positive regulation of Notch signaling pathway, positive regulation of Ras protein signal transduction, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S, positive regulation of epithelial cell migration, positive regulation of epithelial cell proliferation, positive regulation of epithelial cell proliferation involved in wound healing, positive regulation of fibroblast proliferation, positive regulation of hair follicle cell proliferation, positive regulation of keratinocyte migration, positive regulation of keratinocyte proliferation, positive regulation of lymphocyte proliferation, positive regulation of mitotic cell cycle, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of urothelial cell proliferation, positive regulation of vascular endothelial growth factor receptor signaling pathway, positive regulation of white fat cell proliferation, protein localization to cell surface, radial glial cell differentiation, regulation of activin receptor signaling pathway, regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling, regulation of prostatic bud formation, regulation of saliva secretion, regulation of smoothened signaling pathway, response to estradiol stimulus, response to lipopolysaccharide, salivary gland development, secretion by lung epithelial cell involved in lung growth, semicircular canal fusion, smooth muscle cell differentiation, somatic stem cell maintenance, spleen development, submandibular salivary gland formation, tear secretion, thymus development, thyroid gland development, tissue regeneration, urothelial cell proliferation, white fat cell differentiation, wound healing cell surface, extracellular matrix, extracellular region, extracellular space, nucleus, plasma membrane chemoattractant activity, fibroblast growth factor receptor binding, growth factor activity, heparin binding, type 2 fibroblast growth factor receptor binding Human FGF12 PINC UniProtKB {GO:0007507=PMID:10049777, GO:0050905=GO_REF:0000019, GO:0007165=PMID:8790420, GO:0008344=GO_REF:0000019, GO:0010765=GO_REF:0000019, GO:0007267=PMID:8790420, GO:0007268=GO_REF:0000019, GO:0005634=PMID:8790420, GO:0005615=PMID:10049777, GO:2001258=GO_REF:0000019, GO:0008083=GO_REF:0000037, GO:0007399=PMID:8790420} P61328 Fibroblast growth factor 12 protein 20061127 {GO:0007507=TAS, GO:0050905=IEA, GO:0007165=TAS, GO:0008344=IEA, GO:0010765=IEA, GO:0007267=TAS, GO:0007268=IEA, GO:0005634=IDA, GO:0005615=TAS, GO:2001258=IEA, GO:0008083=IEA, GO:0007399=TAS} adult locomotory behavior, cell-cell signaling, heart development, negative regulation of cation channel activity, nervous system development, neuromuscular process, positive regulation of sodium ion transport, signal transduction, synaptic transmission extracellular space, nucleus growth factor activity Human FGF13 GOC UniProtKB {GO:0008017=GO_REF:0000024, GO:0005515=PMID:15282281, GO:0030424=GO_REF:0000024, GO:0043005=GO_REF:0000024, GO:0005886=GO_REF:0000024, GO:0007267=PMID:8790420, GO:0005634=PMID:8790420, GO:0030175=GO_REF:0000024, GO:0030425=GO_REF:0000024, GO:0048671=GO_REF:0000024, GO:0030426=GO_REF:0000024, GO:0005737=PMID:12244047, GO:0021795=GO_REF:0000024, GO:0014704=GO_REF:0000024, GO:0000165=PMID:12244047, GO:0045860=PMID:12244047, GO:0007613=GO_REF:0000024, GO:0007612=GO_REF:0000024, GO:0005874=GO_REF:0000024, GO:0048487=GO_REF:0000024, GO:0005730=GO_REF:0000039, GO:0030295=PMID:12244047, GO:0045200=GO_REF:0000024, GO:0072659=GO_REF:0000024, GO:0007399=PMID:8790420, GO:0044325=GO_REF:0000024, GO:0007165=PMID:8790420, GO:0021766=GO_REF:0000024, GO:0046785=GO_REF:0000024, GO:0007026=GO_REF:0000024, GO:0001764=GO_REF:0000024, GO:0008083=GO_REF:0000002, GO:0017080=PMID:15282281} Q92913 Fibroblast growth factor 13 protein 20130413 {GO:0008017=ISS, GO:0005515=IPI, GO:0030424=ISS, GO:0043005=ISS, GO:0005886=ISS, GO:0007267=TAS, GO:0005634=IDA, GO:0030175=ISS, GO:0030425=ISS, GO:0048671=ISS, GO:0030426=ISS, GO:0005737=IPI, GO:0021795=ISS, GO:0014704=ISS, GO:0000165=IDA, GO:0045860=IGI, GO:0007613=ISS, GO:0007612=ISS, GO:0005874=ISS, GO:0048487=ISS, GO:0005730=IEA, GO:0030295=IGI, GO:0045200=ISS, GO:0072659=ISS, GO:0007399=TAS, GO:0044325=ISS, GO:0007165=TAS, GO:0021766=ISS, GO:0046785=ISS, GO:0007026=ISS, GO:0001764=ISS, GO:0008083=IEA, GO:0017080=IDA} MAPK cascade, cell-cell signaling, cerebral cortex cell migration, establishment of neuroblast polarity, hippocampus development, learning, memory, microtubule polymerization, negative regulation of collateral sprouting, negative regulation of microtubule depolymerization, nervous system development, neuron migration, positive regulation of protein kinase activity, protein localization to plasma membrane, signal transduction axon, cytoplasm, dendrite, filopodium, growth cone, intercalated disc, microtubule, neuron projection, nucleolus, nucleus, plasma membrane beta-tubulin binding, growth factor activity, ion channel binding, microtubule binding, protein binding, protein kinase activator activity, sodium channel regulator activity Human UniProtKB:Q13387-2 FGF16 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0048011=Reactome:REACT_11061, GO:0048015=Reactome:REACT_12464, GO:0007267=PMID:9473496, GO:0005576=Reactome:REACT_121127, GO:0005615=PMID:9473496, GO:0009266=PMID:9473496, GO:0007165=PMID:9473496, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9510, GO:0045087=Reactome:REACT_6802, GO:0008152=PMID:9473496, GO:0009887=PMID:9473496, GO:0008083=GO_REF:0000037} O43320 Fibroblast growth factor 16 protein 20110530 {GO:0008286=TAS, GO:0048011=TAS, GO:0048015=TAS, GO:0007267=TAS, GO:0005576=TAS, GO:0005615=TAS, GO:0009266=TAS, GO:0007165=TAS, GO:0007173=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0008152=TAS, GO:0009887=TAS, GO:0008083=IEA} cell-cell signaling, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, metabolic process, neurotrophin TRK receptor signaling pathway, organ morphogenesis, phosphatidylinositol-mediated signaling, response to temperature stimulus, signal transduction extracellular region, extracellular space growth factor activity Human FGF17 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0048011=Reactome:REACT_11061, GO:0008284=GO_REF:0000019, GO:0048015=Reactome:REACT_12464, GO:0005111=PMID:16384934, GO:0007267=PMID:9514906, GO:0005576=Reactome:REACT_147854, GO:0005105=PMID:16384934, GO:0005615=PMID:9514906, GO:0007399=PMID:9514906, GO:0007165=PMID:9514906, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9515, GO:0045087=Reactome:REACT_6802, GO:0008083=GO_REF:0000037} O60258 Fibroblast growth factor 17 protein 20130301 {GO:0008286=TAS, GO:0048011=TAS, GO:0008284=IEA, GO:0048015=TAS, GO:0005111=IDA, GO:0007267=TAS, GO:0005576=TAS, GO:0005105=IDA, GO:0005615=TAS, GO:0007399=TAS, GO:0007165=TAS, GO:0007173=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0008083=IEA} cell-cell signaling, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, nervous system development, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of cell proliferation, signal transduction extracellular region, extracellular space growth factor activity, type 1 fibroblast growth factor receptor binding, type 2 fibroblast growth factor receptor binding Human FGF18 LIFEdb UniProtKB {GO:0008286=Reactome:REACT_498, GO:0030949=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0030324=GO_REF:0000019, GO:0005111=PMID:16384934, GO:0007267=PMID:9742123, GO:0009653=PMID:9742123, GO:0005615=PMID:9742123, GO:0002063=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0032332=GO_REF:0000019, GO:0070374=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0048015=Reactome:REACT_12464, GO:0005730=GO_REF:0000054, GO:0005576=Reactome:REACT_147854, GO:0005105=PMID:16384934, GO:0001525=GO_REF:0000019, GO:0007399=GO_REF:0000019, GO:0007165=PMID:9742123, GO:0001958=GO_REF:0000019, GO:0001957=GO_REF:0000019, GO:0008543=Reactome:REACT_9510, GO:0045087=Reactome:REACT_6802, GO:0008083=GO_REF:0000037} O76093 Fibroblast growth factor 18 protein 20100607 {GO:0008286=TAS, GO:0030949=IEA, GO:0008284=IEA, GO:0030324=IEA, GO:0005111=IDA, GO:0007267=TAS, GO:0009653=TAS, GO:0005615=TAS, GO:0002063=IEA, GO:0007173=TAS, GO:0032332=IEA, GO:0070374=IEA, GO:0048011=TAS, GO:0048015=TAS, GO:0005730=IDA, GO:0005576=TAS, GO:0005105=IDA, GO:0001525=IEA, GO:0007399=IEA, GO:0007165=TAS, GO:0001958=IEA, GO:0001957=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:0008083=IEA} anatomical structure morphogenesis, angiogenesis, cell-cell signaling, chondrocyte development, endochondral ossification, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, intramembranous ossification, lung development, nervous system development, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of ERK1 and ERK2 cascade, positive regulation of cell proliferation, positive regulation of chondrocyte differentiation, positive regulation of vascular endothelial growth factor receptor signaling pathway, signal transduction extracellular region, extracellular space, nucleolus growth factor activity, type 1 fibroblast growth factor receptor binding, type 2 fibroblast growth factor receptor binding Human FGF19 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005515=PMID:18829467, GO:0048011=Reactome:REACT_11061, GO:0008284=PMID:18187602, GO:0048015=Reactome:REACT_12464, GO:0001755=GO_REF:0000019, GO:0046330=PMID:12815072, GO:0005104=PMID:10525310, GO:0005576=Reactome:REACT_147854, GO:0070858=PMID:12815072, GO:0007399=PMID:9931477, GO:0007507=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0046326=PMID:17623664, GO:0070374=PMID:17623664, GO:0008083=GO_REF:0000037} O95750 Fibroblast growth factor 19 protein 20130301 {GO:0008286=TAS, GO:0005515=IPI, GO:0048011=TAS, GO:0008284=IGI, GO:0048015=TAS, GO:0001755=IEA, GO:0046330=IDA, GO:0005104=IPI, GO:0005576=TAS, GO:0070858=IDA, GO:0007399=TAS, GO:0007507=IEA, GO:0007173=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0046326=IDA, GO:0070374=IDA, GO:0008083=IEA} epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, heart development, innate immune response, insulin receptor signaling pathway, negative regulation of bile acid biosynthetic process, nervous system development, neural crest cell migration, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of ERK1 and ERK2 cascade, positive regulation of JNK cascade, positive regulation of cell proliferation, positive regulation of glucose import extracellular region fibroblast growth factor receptor binding, growth factor activity, protein binding Human FGF2 GOC UniProtKB {GO:0060045=PMID:9553078, GO:0005515=PMID:18329368, GO:0030308=GO_REF:0000019, GO:0001658=PMID:12631064, GO:0001759=GO_REF:0000019, GO:0048598=PMID:20011604, GO:0048678=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0060644=GO_REF:0000019, GO:0043552=PMID:20011604, GO:0010764=PMID:19577615, GO:0006935=PMID:10848592, GO:0007173=Reactome:REACT_9417, GO:0032958=PMID:20011604, GO:0061045=PMID:19577615, GO:0060548=PMID:12631064, GO:0009887=PMID:10903182, GO:0051781=GO_REF:0000037, GO:0070374=PMID:17167778, GO:0051209=PMID:20011604, GO:0017134=GO_REF:0000019, GO:0043536=PMID:18555217, GO:0008543=Reactome:REACT_9515, GO:0045087=Reactome:REACT_6802, GO:0042060=PMID:20011604, GO:0006700=GO_REF:0000019, GO:0010001=GO_REF:0000019, GO:0045893=PMID:17500071, GO:0045892=GO_REF:0000019, GO:0043537=PMID:18555217, GO:0008286=Reactome:REACT_498, GO:0008284=PMID:8663044, GO:0008285=GO_REF:0000019, GO:0060591=PMID:17167778, GO:0030324=GO_REF:0000019, GO:0002042=PMID:19351956, GO:0021940=GO_REF:0000019, GO:0042660=PMID:18635606, GO:0007265=PMID:10848592, GO:0060129=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0048864=GO_REF:0000019, GO:0060128=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0000187=PMID:9712850, GO:0000186=GO_REF:0000019, GO:0030374=PMID:17500071, GO:0051726=GO_REF:0000019, GO:0008201=GO_REF:0000037, GO:0048011=Reactome:REACT_11061, GO:0006661=PMID:20011604, GO:0048015=Reactome:REACT_12464, GO:0006915=GO_REF:0000019, GO:0045765=PMID:20011604, GO:0005576=Reactome:REACT_147854, GO:0005104=PMID:10830168, GO:0000189=GO_REF:0000019, GO:0045766=PMID:20011604, GO:0050918=PMID:18059339, GO:0007399=PMID:9576942, GO:0010863=PMID:20011604, GO:0045669=GO_REF:0000019, GO:0007165=PMID:9712850, GO:0021762=GO_REF:0000019, GO:0030214=PMID:19577615, GO:0046668=GO_REF:0000019} P09038 Fibroblast growth factor 2 protein 20130413 {GO:0060045=IDA, GO:0005515=IPI, GO:0030308=IEA, GO:0001658=IDA, GO:0001759=IEA, GO:0048598=TAS, GO:0048678=IEA, GO:0005615=IEA, GO:0060644=IEA, GO:0043552=IDA, GO:0010764=IDA, GO:0006935=TAS, GO:0007173=TAS, GO:0032958=IDA, GO:0061045=IDA, GO:0060548=IDA, GO:0009887=TAS, GO:0051781=IEA, GO:0070374=IDA, GO:0051209=IDA, GO:0017134=IEA, GO:0043536=IDA, GO:0008543=TAS, GO:0045087=TAS, GO:0042060=TAS, GO:0006700=IEA, GO:0010001=IEA, GO:0045893=IDA, GO:0045892=IEA, GO:0043537=IDA, GO:0008286=TAS, GO:0008284=IGI, GO:0008285=IEA, GO:0060591=IDA, GO:0030324=IEA, GO:0002042=IGI, GO:0021940=IEA, GO:0042660=IDA, GO:0007265=TAS, GO:0060129=IEA, GO:0005634=IEA, GO:0048864=IEA, GO:0060128=IEA, GO:0005829=IEA, GO:0000187=TAS, GO:0000186=IEA, GO:0030374=IDA, GO:0051726=IEA, GO:0008201=IEA, GO:0048011=TAS, GO:0006661=IDA, GO:0048015=TAS, GO:0006915=IEA, GO:0045765=TAS, GO:0005576=TAS, GO:0005104=IPI, GO:0000189=IEA, GO:0045766=IDA, GO:0050918=IDA, GO:0007399=TAS, GO:0010863=IDA, GO:0045669=IEA, GO:0007165=NAS, GO:0021762=IEA, GO:0030214=IDA, GO:0046668=IEA} C21-steroid hormone biosynthetic process, MAPK import into nucleus, Ras protein signal transduction, activation of MAPK activity, activation of MAPKK activity, apoptotic process, branching involved in ureteric bud morphogenesis, cell migration involved in sprouting angiogenesis, chemotaxis, chondroblast differentiation, corticotropin hormone secreting cell differentiation, embryonic morphogenesis, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, glial cell differentiation, hyaluronan catabolic process, innate immune response, inositol phosphate biosynthetic process, insulin receptor signaling pathway, lung development, mammary gland epithelial cell differentiation, negative regulation of blood vessel endothelial cell migration, negative regulation of cell death, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of fibroblast migration, negative regulation of transcription, DNA-dependent, negative regulation of wound healing, nervous system development, neurotrophin TRK receptor signaling pathway, organ induction, organ morphogenesis, phosphatidylinositol biosynthetic process, phosphatidylinositol-mediated signaling, positive chemotaxis, positive regulation of ERK1 and ERK2 cascade, positive regulation of angiogenesis, positive regulation of blood vessel endothelial cell migration, positive regulation of cardiac muscle cell proliferation, positive regulation of cell division, positive regulation of cell fate specification, positive regulation of cell proliferation, positive regulation of cerebellar granule cell precursor proliferation, positive regulation of osteoblast differentiation, positive regulation of phosphatidylinositol 3-kinase activity, positive regulation of phospholipase C activity, positive regulation of transcription, DNA-dependent, regulation of angiogenesis, regulation of cell cycle, regulation of retinal cell programmed cell death, release of sequestered calcium ion into cytosol, response to axon injury, signal transduction, stem cell development, substantia nigra development, thyroid-stimulating hormone-secreting cell differentiation, wound healing cytosol, extracellular region, extracellular space, nucleus fibroblast growth factor binding, fibroblast growth factor receptor binding, heparin binding, ligand-dependent nuclear receptor transcription coactivator activity, protein binding Human FGF20 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0048011=Reactome:REACT_11061, GO:0008284=GO_REF:0000019, GO:0060113=GO_REF:0000019, GO:0048015=Reactome:REACT_12464, GO:0060043=GO_REF:0000019, GO:0007267=PMID:10913340, GO:0005104=GO_REF:0000019, GO:0005576=Reactome:REACT_120860, GO:0007165=PMID:10913340, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9515, GO:0045087=Reactome:REACT_6802, GO:0070374=GO_REF:0000019, GO:0008083=GO_REF:0000019} Q9NP95 Fibroblast growth factor 20 protein 20110530 {GO:0008286=TAS, GO:0048011=TAS, GO:0008284=IEA, GO:0060113=IEA, GO:0048015=TAS, GO:0060043=IEA, GO:0007267=TAS, GO:0005104=IEA, GO:0005576=TAS, GO:0007165=TAS, GO:0007173=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0070374=IEA, GO:0008083=IEA} cell-cell signaling, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, inner ear receptor cell differentiation, insulin receptor signaling pathway, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of ERK1 and ERK2 cascade, positive regulation of cell proliferation, regulation of cardiac muscle cell proliferation, signal transduction extracellular region fibroblast growth factor receptor binding, growth factor activity Human FGF21 BHF-UCL UniProtKB {GO:0005515=PMID:19117008, GO:0007165=PMID:10858549, GO:0046326=PMID:17623664, GO:0007267=PMID:10858549, GO:0010988=PMID:22378787, GO:0005576=GO_REF:0000039, GO:0005104=GO_REF:0000002, GO:0045716=PMID:22378787, GO:0070374=PMID:17623664, GO:0008083=GO_REF:0000037} Q9NSA1 Fibroblast growth factor 21 protein 20120601 {GO:0005515=IPI, GO:0007165=TAS, GO:0046326=IDA, GO:0007267=TAS, GO:0010988=NAS, GO:0005576=IEA, GO:0005104=IEA, GO:0045716=NAS, GO:0070374=IDA, GO:0008083=IEA} cell-cell signaling, positive regulation of ERK1 and ERK2 cascade, positive regulation of glucose import, positive regulation of low-density lipoprotein particle receptor biosynthetic process, regulation of low-density lipoprotein particle clearance, signal transduction extracellular region fibroblast growth factor receptor binding, growth factor activity, protein binding Human FGF22 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0048011=Reactome:REACT_11061, GO:0005794=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0048015=Reactome:REACT_12464, GO:0005730=GO_REF:0000019, GO:0005576=Reactome:REACT_111238, GO:0005615=PMID:11342227, GO:0030154=PMID:11342227, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9483, GO:0045087=Reactome:REACT_6802, GO:0008083=GO_REF:0000037} Q9HCT0 Fibroblast growth factor 22 protein 20110530 {GO:0008286=TAS, GO:0048011=TAS, GO:0005794=IEA, GO:0009986=IEA, GO:0048015=TAS, GO:0005730=IEA, GO:0005576=TAS, GO:0005615=NAS, GO:0030154=NAS, GO:0007173=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0008083=IEA} cell differentiation, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling Golgi apparatus, cell surface, extracellular region, extracellular space, nucleolus growth factor activity Human FGF23 BHF-UCL UniProtKB {GO:0008286=Reactome:REACT_498, GO:0048011=Reactome:REACT_11061, GO:0048015=Reactome:REACT_12464, GO:0042369=PMID:15040831, GO:0055062=PMID:11062477, GO:0005576=Reactome:REACT_120860, GO:0005105=GO_REF:0000019, GO:0006796=GO_REF:0000019, GO:0030502=PMID:18282132, GO:0005615=PMID:22261194, GO:0030154=GO_REF:0000029, GO:0046888=GO_REF:0000024, GO:0010980=PMID:15040831, GO:0045668=PMID:18282132, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9515, GO:0030643=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0070374=GO_REF:0000019, GO:0045893=GO_REF:0000019, GO:0008083=GO_REF:0000037, GO:0090080=GO_REF:0000019, GO:0010966=PMID:11409890} Q9GZV9 Fibroblast growth factor 23 protein 20120228 {GO:0008286=TAS, GO:0048011=TAS, GO:0048015=TAS, GO:0042369=IDA, GO:0055062=IMP, GO:0005576=TAS, GO:0005105=IEA, GO:0006796=IEA, GO:0030502=IDA, GO:0005615=ISS, GO:0030154=NAS, GO:0046888=ISS, GO:0010980=IDA, GO:0045668=IDA, GO:0007173=TAS, GO:0008543=TAS, GO:0030643=IEA, GO:0045087=TAS, GO:0070374=IEA, GO:0045893=IEA, GO:0008083=IEA, GO:0090080=IEA, GO:0010966=IDA} cell differentiation, cellular phosphate ion homeostasis, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, negative regulation of bone mineralization, negative regulation of hormone secretion, negative regulation of osteoblast differentiation, neurotrophin TRK receptor signaling pathway, phosphate ion homeostasis, phosphate-containing compound metabolic process, phosphatidylinositol-mediated signaling, positive regulation of ERK1 and ERK2 cascade, positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway, positive regulation of transcription, DNA-dependent, positive regulation of vitamin D 24-hydroxylase activity, regulation of phosphate transport, vitamin D catabolic process extracellular region, extracellular space growth factor activity, type 1 fibroblast growth factor receptor binding Human UniProtKB:F1SKZ1 FGF3 BHF-UCL UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005515=PMID:16263090, GO:0048011=Reactome:REACT_11061, GO:0008284=PMID:8663044, GO:0005794=GO_REF:0000019, GO:0048015=Reactome:REACT_12464, GO:0030916=GO_REF:0000019, GO:0007267=PMID:2470007, GO:0005576=Reactome:REACT_147854, GO:0048538=GO_REF:0000019, GO:0001759=GO_REF:0000019, GO:0048752=GO_REF:0000019, GO:0009653=PMID:2470007, GO:0036342=GO_REF:0000019, GO:0007165=PMID:2470007, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9483, GO:0045087=Reactome:REACT_6802, GO:0051781=GO_REF:0000037, GO:0008083=GO_REF:0000037, GO:0055026=PMID:20702560} P11487 Fibroblast growth factor 3 protein 20110418 {GO:0008286=TAS, GO:0005515=IPI, GO:0048011=TAS, GO:0008284=IGI, GO:0005794=IEA, GO:0048015=TAS, GO:0030916=IEA, GO:0007267=TAS, GO:0005576=TAS, GO:0048538=IEA, GO:0001759=IEA, GO:0048752=IEA, GO:0009653=TAS, GO:0036342=IEA, GO:0007165=TAS, GO:0007173=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0051781=IEA, GO:0008083=IEA, GO:0055026=IMP} anatomical structure morphogenesis, cell-cell signaling, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, negative regulation of cardiac muscle tissue development, neurotrophin TRK receptor signaling pathway, organ induction, otic vesicle formation, phosphatidylinositol-mediated signaling, positive regulation of cell division, positive regulation of cell proliferation, post-anal tail morphogenesis, semicircular canal morphogenesis, signal transduction, thymus development Golgi apparatus, extracellular region growth factor activity, protein binding Human FGF4 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0008284=PMID:8663044, GO:0060591=PMID:17167778, GO:0010463=PMID:11023873, GO:0007267=PMID:2959959, GO:0005634=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0045944=GO_REF:0000019, GO:0042475=GO_REF:0000019, GO:0051781=GO_REF:0000037, GO:0070374=PMID:17167778, GO:0008201=GO_REF:0000037, GO:0048011=Reactome:REACT_11061, GO:0043066=GO_REF:0000019, GO:0048015=Reactome:REACT_12464, GO:0005104=GO_REF:0000019, GO:0060561=GO_REF:0000019, GO:0005576=Reactome:REACT_147854, GO:0007165=PMID:2959959, GO:0060363=GO_REF:0000019, GO:0001502=GO_REF:0000019, GO:0008543=Reactome:REACT_9515, GO:0045087=Reactome:REACT_6802, GO:0019827=GO_REF:0000019, GO:0035116=GO_REF:0000019, GO:0001934=GO_REF:0000019, GO:0008083=GO_REF:0000037} P08620 Fibroblast growth factor 4 protein 20130301 {GO:0008286=TAS, GO:0008284=IGI, GO:0060591=IDA, GO:0010463=IDA, GO:0007267=TAS, GO:0005634=IEA, GO:0005829=IEA, GO:0007173=TAS, GO:0045944=IEA, GO:0042475=IEA, GO:0051781=IEA, GO:0070374=IDA, GO:0008201=IEA, GO:0048011=TAS, GO:0043066=IEA, GO:0048015=TAS, GO:0005104=IEA, GO:0060561=IEA, GO:0005576=TAS, GO:0007165=TAS, GO:0060363=IEA, GO:0001502=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:0019827=IEA, GO:0035116=IEA, GO:0001934=IEA, GO:0008083=IEA} apoptotic process involved in morphogenesis, cartilage condensation, cell-cell signaling, chondroblast differentiation, cranial suture morphogenesis, embryonic hindlimb morphogenesis, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, mesenchymal cell proliferation, negative regulation of apoptotic process, neurotrophin TRK receptor signaling pathway, odontogenesis of dentin-containing tooth, phosphatidylinositol-mediated signaling, positive regulation of ERK1 and ERK2 cascade, positive regulation of cell division, positive regulation of cell proliferation, positive regulation of protein phosphorylation, positive regulation of transcription from RNA polymerase II promoter, signal transduction, stem cell maintenance cytosol, extracellular region, nucleus fibroblast growth factor receptor binding, growth factor activity, heparin binding Human FGF5 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0048011=Reactome:REACT_11061, GO:0008284=PMID:8663044, GO:0023019=GO_REF:0000019, GO:0008283=PMID:3211147, GO:0048015=Reactome:REACT_12464, GO:0007267=PMID:9786939, GO:0005104=PMID:8386828, GO:0005576=Reactome:REACT_147854, GO:0005615=PMID:9786939, GO:0007399=PMID:9786939, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9515, GO:0045087=Reactome:REACT_6802, GO:0010001=GO_REF:0000019, GO:0051781=GO_REF:0000037, GO:0008083=GO_REF:0000037} P12034 Fibroblast growth factor 5 protein 20130301 {GO:0008286=TAS, GO:0048011=TAS, GO:0008284=IGI, GO:0023019=IEA, GO:0008283=TAS, GO:0048015=TAS, GO:0007267=TAS, GO:0005104=IDA, GO:0005576=TAS, GO:0005615=TAS, GO:0007399=TAS, GO:0007173=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0010001=IEA, GO:0051781=IEA, GO:0008083=IEA} cell proliferation, cell-cell signaling, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, glial cell differentiation, innate immune response, insulin receptor signaling pathway, nervous system development, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of cell division, positive regulation of cell proliferation, signal transduction involved in regulation of gene expression extracellular region, extracellular space fibroblast growth factor receptor binding, growth factor activity Human FGF6 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0048011=Reactome:REACT_11061, GO:0008284=PMID:8663044, GO:0008283=PMID:2649847, GO:0048015=Reactome:REACT_12464, GO:0007267=PMID:2649847, GO:0005576=Reactome:REACT_147854, GO:0001525=GO_REF:0000037, GO:0005615=GO_REF:0000039, GO:0042383=GO_REF:0000019, GO:0007165=PMID:2649847, GO:0007173=Reactome:REACT_9417, GO:0001502=GO_REF:0000019, GO:0008543=Reactome:REACT_9515, GO:0045087=Reactome:REACT_6802, GO:0051781=GO_REF:0000037, GO:0045445=GO_REF:0000019, GO:0008083=GO_REF:0000037} P10767 Fibroblast growth factor 6 protein 20130301 {GO:0008286=TAS, GO:0048011=TAS, GO:0008284=IGI, GO:0008283=TAS, GO:0048015=TAS, GO:0007267=TAS, GO:0005576=TAS, GO:0001525=IEA, GO:0005615=IEA, GO:0042383=IEA, GO:0007165=TAS, GO:0007173=TAS, GO:0001502=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:0051781=IEA, GO:0045445=IEA, GO:0008083=IEA} angiogenesis, cartilage condensation, cell proliferation, cell-cell signaling, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, myoblast differentiation, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of cell division, positive regulation of cell proliferation, signal transduction extracellular region, extracellular space, sarcolemma growth factor activity Human FGF7 IntAct UniProtKB {GO:0005515=PMID:1309608, GO:0008286=Reactome:REACT_498, GO:0010838=PMID:17449030, GO:0008284=PMID:8663044, GO:0051549=PMID:17449030, GO:0010463=PMID:11023837, GO:0050731=PMID:17449030, GO:0031069=GO_REF:0000019, GO:0060665=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0060501=PMID:9740653, GO:0051781=GO_REF:0000037, GO:0008201=GO_REF:0000037, GO:0050679=PMID:11493558, GO:0048011=Reactome:REACT_11061, GO:0005794=GO_REF:0000019, GO:0031532=PMID:17449030, GO:0048015=Reactome:REACT_12464, GO:0009611=PMID:7973639, GO:0005576=Reactome:REACT_147854, GO:0042056=PMID:17449030, GO:0050918=PMID:17449030, GO:0007165=PMID:2475908, GO:0008544=PMID:7973639, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0034394=PMID:17449030, GO:0008083=GO_REF:0000037, GO:0061033=PMID:10541313, GO:0060445=GO_REF:0000019} P21781 Fibroblast growth factor 7 protein 20130415 {GO:0005515=IPI, GO:0008286=TAS, GO:0010838=IDA, GO:0008284=IGI, GO:0051549=IDA, GO:0010463=IDA, GO:0050731=IDA, GO:0031069=IEA, GO:0060665=IEA, GO:0007173=TAS, GO:0060501=IDA, GO:0051781=IEA, GO:0008201=IEA, GO:0050679=IDA, GO:0048011=TAS, GO:0005794=IEA, GO:0031532=IDA, GO:0048015=TAS, GO:0009611=TAS, GO:0005576=TAS, GO:0042056=IDA, GO:0050918=IDA, GO:0007165=NAS, GO:0008544=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0034394=IDA, GO:0008083=IEA, GO:0061033=IDA, GO:0060445=IEA} actin cytoskeleton reorganization, branching involved in salivary gland morphogenesis, epidermal growth factor receptor signaling pathway, epidermis development, fibroblast growth factor receptor signaling pathway, hair follicle morphogenesis, innate immune response, insulin receptor signaling pathway, mesenchymal cell proliferation, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive chemotaxis, positive regulation of cell division, positive regulation of cell proliferation, positive regulation of epithelial cell proliferation, positive regulation of epithelial cell proliferation involved in lung morphogenesis, positive regulation of keratinocyte migration, positive regulation of keratinocyte proliferation, positive regulation of peptidyl-tyrosine phosphorylation, protein localization to cell surface, regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling, response to wounding, secretion by lung epithelial cell involved in lung growth, signal transduction Golgi apparatus, extracellular region chemoattractant activity, growth factor activity, heparin binding, protein binding Human UniProtKB:P21802-3 FGF8 BHF-UCL UniProtKB {GO:0001656=PMID:18437684, GO:0008406=PMID:18596921, GO:0001658=GO_REF:0000019, GO:0030878=GO_REF:0000019, GO:0001759=GO_REF:0000019, GO:0009653=PMID:8595889, GO:0001947=GO_REF:0000019, GO:0030539=GO_REF:0000019, GO:0043524=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0021798=GO_REF:0000019, GO:0000165=GO_REF:0000019, GO:0051781=GO_REF:0000037, GO:0021543=GO_REF:0000019, GO:0023019=GO_REF:0000019, GO:0030916=GO_REF:0000019, GO:0021544=GO_REF:0000019, GO:0045840=GO_REF:0000019, GO:0030509=GO_REF:0000019, GO:0060037=GO_REF:0000019, GO:0060348=PMID:18596921, GO:0008543=Reactome:REACT_9515, GO:0045087=Reactome:REACT_6802, GO:0030917=GO_REF:0000019, GO:0008083=GO_REF:0000037, GO:0060445=GO_REF:0000019, GO:0008286=Reactome:REACT_498, GO:0021846=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0007369=PMID:8700553, GO:0060425=GO_REF:0000019, GO:0001839=GO_REF:0000019, GO:0060129=GO_REF:0000019, GO:0060128=GO_REF:0000019, GO:0008078=GO_REF:0000019, GO:0042476=PMID:17394220, GO:0060070=GO_REF:0000019, GO:0055026=PMID:20702560, GO:0048011=Reactome:REACT_11061, GO:0001569=GO_REF:0000019, GO:0090134=GO_REF:0000019, GO:0046622=GO_REF:0000019, GO:0003198=GO_REF:0000024, GO:0048015=Reactome:REACT_12464, GO:0001823=PMID:18437684, GO:0035909=GO_REF:0000019, GO:0060563=PMID:17309880, GO:0006915=GO_REF:0000019, GO:0005576=Reactome:REACT_147854, GO:0048853=GO_REF:0000019, GO:0010628=GO_REF:0000019, GO:0001974=GO_REF:0000019, GO:0071542=PMID:15193767, GO:0003148=GO_REF:0000024, GO:0035116=GO_REF:0000019, GO:0042487=GO_REF:0000019} P55075 Fibroblast growth factor 8 protein 20120727 {GO:0001656=IEP, GO:0008406=IMP, GO:0001658=IEA, GO:0030878=IEA, GO:0001759=IEA, GO:0009653=NAS, GO:0001947=IEA, GO:0030539=IEA, GO:0043524=IEA, GO:0007173=TAS, GO:0021798=IEA, GO:0000165=IEA, GO:0051781=IEA, GO:0021543=IEA, GO:0023019=IEA, GO:0030916=IEA, GO:0021544=IEA, GO:0045840=IEA, GO:0030509=IEA, GO:0060037=IEA, GO:0060348=IMP, GO:0008543=TAS, GO:0045087=TAS, GO:0030917=IEA, GO:0008083=IEA, GO:0060445=IEA, GO:0008286=TAS, GO:0021846=IEA, GO:0008284=IEA, GO:0007369=NAS, GO:0060425=IEA, GO:0001839=IEA, GO:0060129=IEA, GO:0060128=IEA, GO:0008078=IEA, GO:0042476=IEP, GO:0060070=IEA, GO:0055026=IMP, GO:0048011=TAS, GO:0001569=IEA, GO:0090134=IEA, GO:0046622=IEA, GO:0003198=ISS, GO:0048015=TAS, GO:0001823=IEP, GO:0035909=IEA, GO:0060563=IDA, GO:0006915=IEA, GO:0005576=TAS, GO:0048853=IEA, GO:0010628=IEA, GO:0001974=IEA, GO:0071542=IDA, GO:0003148=ISS, GO:0035116=IEA, GO:0042487=IEA} BMP signaling pathway, MAPK cascade, anatomical structure morphogenesis, aorta morphogenesis, apoptotic process, blood vessel remodeling, bone development, branching involved in salivary gland morphogenesis, branching involved in ureteric bud morphogenesis, canonical Wnt receptor signaling pathway, cell migration involved in mesendoderm migration, cell proliferation in forebrain, corticotropin hormone secreting cell differentiation, dopaminergic neuron differentiation, embryonic hindlimb morphogenesis, epidermal growth factor receptor signaling pathway, epithelial to mesenchymal transition involved in endocardial cushion formation, fibroblast growth factor receptor signaling pathway, forebrain dorsal/ventral pattern formation, forebrain morphogenesis, gastrulation, gonad development, heart looping, innate immune response, insulin receptor signaling pathway, lung morphogenesis, male genitalia development, mesodermal cell migration, mesonephros development, metanephros development, midbrain-hindbrain boundary development, negative regulation of cardiac muscle tissue development, negative regulation of neuron apoptotic process, neural plate morphogenesis, neuroepithelial cell differentiation, neurotrophin TRK receptor signaling pathway, odontogenesis, organ induction, otic vesicle formation, outflow tract septum morphogenesis, pallium development, patterning of blood vessels, pharyngeal system development, phosphatidylinositol-mediated signaling, positive regulation of cell division, positive regulation of cell proliferation, positive regulation of gene expression, positive regulation of mitosis, positive regulation of organ growth, regulation of odontogenesis of dentin-containing tooth, signal transduction involved in regulation of gene expression, subpallium development, thyroid gland development, thyroid-stimulating hormone-secreting cell differentiation extracellular region growth factor activity Human UniProtKB:P37237 FGF9 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0060045=GO_REF:0000019, GO:0030949=GO_REF:0000019, GO:0008284=PMID:8321227, GO:0090263=GO_REF:0000019, GO:0007267=GO_REF:0000019, GO:0030178=GO_REF:0000019, GO:0048706=GO_REF:0000019, GO:0030326=GO_REF:0000019, GO:0006606=GO_REF:0000019, GO:0005615=PMID:8321227, GO:0045880=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0002062=GO_REF:0000019, GO:0030238=GO_REF:0000019, GO:0051781=GO_REF:0000037, GO:0008201=GO_REF:0000037, GO:0050679=GO_REF:0000019, GO:0048505=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0042472=GO_REF:0000019, GO:0048015=Reactome:REACT_12464, GO:0005576=Reactome:REACT_9519, GO:0005104=GO_REF:0000019, GO:0002053=GO_REF:0000019, GO:0001525=GO_REF:0000019, GO:0048566=GO_REF:0000019, GO:0001649=GO_REF:0000019, GO:0005604=GO_REF:0000019, GO:0010628=GO_REF:0000019, GO:0007165=PMID:8575785, GO:0008543=Reactome:REACT_9515, GO:0045087=Reactome:REACT_6802, GO:0060484=GO_REF:0000019, GO:0043410=GO_REF:0000019, GO:0008083=GO_REF:0000019, GO:0008584=PMID:17848411} P31371 Fibroblast growth factor 9 protein 20110530 {GO:0008286=TAS, GO:0060045=IEA, GO:0030949=IEA, GO:0008284=IDA, GO:0090263=IEA, GO:0007267=IEA, GO:0030178=IEA, GO:0048706=IEA, GO:0030326=IEA, GO:0006606=IEA, GO:0005615=IDA, GO:0045880=IEA, GO:0005737=IEA, GO:0007173=TAS, GO:0002062=IEA, GO:0030238=IEA, GO:0051781=IEA, GO:0008201=IEA, GO:0050679=IEA, GO:0048505=IEA, GO:0048011=TAS, GO:0042472=IEA, GO:0048015=TAS, GO:0005576=TAS, GO:0005104=IEA, GO:0002053=IEA, GO:0001525=IEA, GO:0048566=IEA, GO:0001649=IEA, GO:0005604=IEA, GO:0010628=IEA, GO:0007165=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0060484=IEA, GO:0043410=IEA, GO:0008083=IEA, GO:0008584=IEP} angiogenesis, cell-cell signaling, chondrocyte differentiation, embryonic digestive tract development, embryonic limb morphogenesis, embryonic skeletal system development, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, inner ear morphogenesis, insulin receptor signaling pathway, lung-associated mesenchyme development, male gonad development, male sex determination, negative regulation of Wnt receptor signaling pathway, neurotrophin TRK receptor signaling pathway, osteoblast differentiation, phosphatidylinositol-mediated signaling, positive regulation of MAPK cascade, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of cardiac muscle cell proliferation, positive regulation of cell division, positive regulation of cell proliferation, positive regulation of epithelial cell proliferation, positive regulation of gene expression, positive regulation of mesenchymal cell proliferation, positive regulation of smoothened signaling pathway, positive regulation of vascular endothelial growth factor receptor signaling pathway, protein import into nucleus, regulation of timing of cell differentiation, signal transduction basement membrane, cytoplasm, extracellular region, extracellular space fibroblast growth factor receptor binding, growth factor activity, heparin binding Human FGFBP1 IntAct UniProtKB {GO:0005515=PMID:16257968, GO:0007165=PMID:1885605, GO:0008284=GO_REF:0000019, GO:0008285=PMID:1885605, GO:0005886=GO_REF:0000039, GO:0045743=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0017134=GO_REF:0000019, GO:0007267=PMID:1885605, GO:0008201=PMID:1885605, GO:0005615=GO_REF:0000039} Q14512 Fibroblast growth factor-binding protein 1 protein 20130415 {GO:0005515=IPI, GO:0007165=NAS, GO:0008284=IEA, GO:0008285=TAS, GO:0005886=IEA, GO:0045743=IEA, GO:0009986=IEA, GO:0017134=IEA, GO:0007267=TAS, GO:0008201=TAS, GO:0005615=IEA} cell-cell signaling, negative regulation of cell proliferation, positive regulation of cell proliferation, positive regulation of fibroblast growth factor receptor signaling pathway, signal transduction cell surface, extracellular space, plasma membrane fibroblast growth factor binding, heparin binding, protein binding Human UniProtKB:P09038 FGFBP2 UniProtKB UniProtKB {GO:0019838=GO_REF:0000037, GO:0005615=GO_REF:0000039} Q9BYJ0 Fibroblast growth factor-binding protein 2 protein 20130413 {GO:0019838=IEA, GO:0005615=IEA} extracellular space growth factor binding Human UniProtKB-SubCell:SL-0112 FGFR1 IntAct UniProtKB {GO:0060045=GO_REF:0000019, GO:0005515=PMID:19665973, GO:0001657=GO_REF:0000019, GO:0007605=GO_REF:0000019, GO:0048705=PMID:15863030, GO:0001759=GO_REF:0000019, GO:0042803=PMID:20133753, GO:0042802=PMID:19696444, GO:0046777=PMID:8622701, GO:0007173=Reactome:REACT_9417, GO:0007411=Reactome:REACT_18266, GO:0000165=PMID:10748122, GO:0002062=GO_REF:0000019, GO:0048339=GO_REF:0000019, GO:0042472=GO_REF:0000019, GO:0017134=PMID:18480409, GO:0010518=PMID:12141425, GO:0018108=PMID:18480409, GO:0014068=PMID:15863030, GO:0000122=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0045787=GO_REF:0000019, GO:0001501=PMID:7874169, GO:0005887=PMID:10918587, GO:0008543=Reactome:REACT_9515, GO:0045087=Reactome:REACT_6802, GO:0010976=GO_REF:0000019, GO:0045595=PMID:12141425, GO:0060484=GO_REF:0000019, GO:0060445=GO_REF:0000019, GO:0008286=Reactome:REACT_498, GO:0021847=GO_REF:0000019, GO:0008284=PMID:8663044, GO:0005886=Reactome:REACT_147854, GO:0005634=GO_REF:0000039, GO:0030326=GO_REF:0000019, GO:0043009=PMID:15863030, GO:0005829=GO_REF:0000039, GO:0048378=GO_REF:0000019, GO:0060665=GO_REF:0000019, GO:0043406=PMID:18480409, GO:0048469=GO_REF:0000019, GO:0042474=GO_REF:0000019, GO:0042473=GO_REF:0000019, GO:0008201=PMID:18480409, GO:0005007=PMID:18480409, GO:0048011=Reactome:REACT_11061, GO:0043066=GO_REF:0000019, GO:0048015=Reactome:REACT_12464, GO:0048762=GO_REF:0000019, GO:0002053=GO_REF:0000019, GO:0005576=PMID:1652059, GO:0001525=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0035607=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0010863=PMID:18480409, GO:0060117=GO_REF:0000019, GO:0016477=PMID:15863030, GO:0045666=PMID:8622701, GO:0016023=GO_REF:0000039, GO:0030901=GO_REF:0000019, GO:0006468=PMID:1846977, GO:0016021=PMID:1652059, GO:0004713=PMID:8622701, GO:0001764=PMID:15863030, GO:0043410=PMID:8622701, GO:0090080=GO_REF:0000019} P11362 Fibroblast growth factor receptor 1 protein 20130415 {GO:0060045=IEA, GO:0005515=IPI, GO:0001657=IEA, GO:0007605=IEA, GO:0048705=TAS, GO:0001759=IEA, GO:0042803=IPI, GO:0042802=IPI, GO:0046777=IDA, GO:0007173=TAS, GO:0007411=TAS, GO:0000165=TAS, GO:0002062=IEA, GO:0048339=IEA, GO:0042472=IEA, GO:0017134=IDA, GO:0010518=TAS, GO:0018108=IDA, GO:0014068=TAS, GO:0000122=IEA, GO:0001701=IEA, GO:0045787=IEA, GO:0001501=TAS, GO:0005887=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0010976=IEA, GO:0045595=TAS, GO:0060484=IEA, GO:0060445=IEA, GO:0008286=TAS, GO:0021847=IEA, GO:0008284=IGI, GO:0005886=TAS, GO:0005634=IEA, GO:0030326=IEA, GO:0043009=TAS, GO:0005829=IEA, GO:0048378=IEA, GO:0060665=IEA, GO:0043406=IDA, GO:0048469=IEA, GO:0042474=IEA, GO:0042473=IEA, GO:0008201=IDA, GO:0005007=IDA, GO:0048011=TAS, GO:0043066=IEA, GO:0048015=TAS, GO:0048762=IEA, GO:0002053=IEA, GO:0005576=NAS, GO:0001525=IEA, GO:0005524=IEA, GO:0035607=IEA, GO:0006351=IEA, GO:0010863=IDA, GO:0060117=IEA, GO:0016477=TAS, GO:0045666=IMP, GO:0016023=IEA, GO:0030901=IEA, GO:0006468=NAS, GO:0016021=NAS, GO:0004713=IDA, GO:0001764=TAS, GO:0043410=IMP, GO:0090080=IEA} MAPK cascade, angiogenesis, auditory receptor cell development, axon guidance, branching involved in salivary gland morphogenesis, cell maturation, cell migration, chondrocyte differentiation, chordate embryonic development, embryonic limb morphogenesis, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development, in utero embryonic development, innate immune response, inner ear morphogenesis, insulin receptor signaling pathway, lung-associated mesenchyme development, mesenchymal cell differentiation, midbrain development, middle ear morphogenesis, negative regulation of apoptotic process, negative regulation of transcription from RNA polymerase II promoter, neuron migration, neurotrophin TRK receptor signaling pathway, organ induction, outer ear morphogenesis, paraxial mesoderm development, peptidyl-tyrosine phosphorylation, phosphatidylinositol-mediated signaling, positive regulation of MAP kinase activity, positive regulation of MAPK cascade, positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway, positive regulation of cardiac muscle cell proliferation, positive regulation of cell cycle, positive regulation of cell proliferation, positive regulation of mesenchymal cell proliferation, positive regulation of neuron differentiation, positive regulation of neuron projection development, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of phospholipase C activity, positive regulation of phospholipase activity, protein autophosphorylation, protein phosphorylation, regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling, regulation of cell differentiation, regulation of lateral mesodermal cell fate specification, sensory perception of sound, skeletal system development, skeletal system morphogenesis, transcription, DNA-dependent, ureteric bud development, ventricular zone neuroblast division cytoplasmic membrane-bounded vesicle, cytosol, extracellular region, integral to membrane, integral to plasma membrane, nucleus, plasma membrane ATP binding, fibroblast growth factor binding, fibroblast growth factor-activated receptor activity, heparin binding, identical protein binding, protein binding, protein homodimerization activity, protein tyrosine kinase activity Human UniProtKB:P11362 FGFR1OP GOC UniProtKB {GO:0005515=PMID:17888034, GO:0005813=PMID:21399614, GO:0008284=PMID:17888034, GO:0048471=PMID:17888034, GO:0030335=PMID:17888034, GO:0034453=GO_REF:0000002, GO:0019901=PMID:17888034, GO:0030307=PMID:17888034, GO:0061099=PMID:17888034, GO:0030292=PMID:17888034, GO:0005634=PMID:17888034, GO:0042803=PMID:16690081, GO:0005829=Reactome:REACT_121382, GO:0000086=Reactome:REACT_2203, GO:0004713=Reactome:REACT_121233, GO:0006469=PMID:17888034, GO:0000278=Reactome:REACT_152} O95684 FGFR1 oncogene partner protein 20130413 {GO:0005515=IPI, GO:0005813=IDA, GO:0008284=IDA, GO:0048471=IDA, GO:0030335=IDA, GO:0034453=IEA, GO:0019901=IPI, GO:0030307=IDA, GO:0061099=IDA, GO:0030292=IDA, GO:0005634=IDA, GO:0042803=IDA, GO:0005829=TAS, GO:0000086=TAS, GO:0004713=TAS, GO:0006469=IDA, GO:0000278=TAS} G2/M transition of mitotic cell cycle, microtubule anchoring, mitotic cell cycle, negative regulation of protein kinase activity, negative regulation of protein tyrosine kinase activity, positive regulation of cell growth, positive regulation of cell migration, positive regulation of cell proliferation centrosome, cytosol, nucleus, perinuclear region of cytoplasm protein binding, protein homodimerization activity, protein kinase binding, protein tyrosine kinase activity, protein tyrosine kinase inhibitor activity Human FGFR1OP2 Reactome UniProtKB {GO:0005737=GO_REF:0000019, GO:0042060=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0005829=Reactome:REACT_121382} Q9NVK5 FGFR1 oncogene partner 2 protein 20121108 {GO:0005737=IEA, GO:0042060=IEA, GO:0042803=IEA, GO:0005829=TAS} wound healing cytoplasm, cytosol protein homodimerization activity Human FGFR2 HPA UniProtKB {GO:0005515=PMID:22726438, GO:0060045=GO_REF:0000024, GO:0090263=GO_REF:0000024, GO:0048705=PMID:15190072, GO:0009791=GO_REF:0000024, GO:0048701=PMID:7874170, GO:0021860=GO_REF:0000024, GO:0031069=GO_REF:0000024, GO:0060916=GO_REF:0000024, GO:0060915=GO_REF:0000024, GO:0046777=PMID:15629145, GO:0005794=GO_REF:0000039, GO:0042472=GO_REF:0000024, GO:0051150=GO_REF:0000024, GO:0009986=PMID:12493773, GO:0010518=PMID:16844695, GO:0018108=PMID:16844695, GO:0001701=GO_REF:0000024, GO:0060442=GO_REF:0000024, GO:0060348=GO_REF:0000024, GO:0045165=GO_REF:0000024, GO:0005887=PMID:16844695, GO:0045087=Reactome:REACT_6802, GO:0060349=GO_REF:0000024, GO:0060449=GO_REF:0000024, GO:0060445=GO_REF:0000024, GO:0060595=GO_REF:0000024, GO:0060529=GO_REF:0000024, GO:0021847=GO_REF:0000024, GO:0030177=GO_REF:0000024, GO:0005634=PMID:17471512, GO:0007528=GO_REF:0000019, GO:0060664=GO_REF:0000024, GO:0060667=GO_REF:0000024, GO:0048568=GO_REF:0000024, GO:0040014=GO_REF:0000024, GO:0042476=GO_REF:0000024, GO:0060523=GO_REF:0000024, GO:0060527=GO_REF:0000024, GO:0035604=GO_REF:0000024, GO:0048011=Reactome:REACT_11061, GO:0035603=GO_REF:0000024, GO:0035602=GO_REF:0000024, GO:0048015=Reactome:REACT_12464, GO:0048762=GO_REF:0000024, GO:0005576=GO_REF:0000039, GO:0048565=GO_REF:0000024, GO:0035607=GO_REF:0000024, GO:0048562=GO_REF:0000024, GO:0032808=GO_REF:0000024, GO:0045667=PMID:15190072, GO:0016020=PMID:8676562, GO:0040036=GO_REF:0000024, GO:0048557=GO_REF:0000024, GO:0060463=GO_REF:0000024, GO:0060512=GO_REF:0000024, GO:0016023=GO_REF:0000039, GO:0030901=GO_REF:0000024, GO:0048755=GO_REF:0000024, GO:0016021=PMID:1697263, GO:0061031=GO_REF:0000019, GO:0001657=GO_REF:0000024, GO:0033688=PMID:15190072, GO:0055010=GO_REF:0000024, GO:0070307=GO_REF:0000019, GO:0060670=GO_REF:0000024, GO:0007409=GO_REF:0000024, GO:0042803=PMID:16844695, GO:0042802=PMID:22726438, GO:0009880=GO_REF:0000024, GO:0048608=GO_REF:0000024, GO:0007173=Reactome:REACT_9417, GO:0060501=GO_REF:0000024, GO:0009887=GO_REF:0000024, GO:0051781=GO_REF:0000024, GO:0060601=GO_REF:0000024, GO:0070374=GO_REF:0000024, GO:0070372=GO_REF:0000024, GO:0005938=PMID:17471512, GO:0050679=GO_REF:0000024, GO:0048286=GO_REF:0000024, GO:0017134=PMID:8386828, GO:0010453=GO_REF:0000024, GO:0030916=GO_REF:0000024, GO:0048489=GO_REF:0000019, GO:0000122=GO_REF:0000024, GO:0060688=GO_REF:0000024, GO:0045787=GO_REF:0000024, GO:0060076=GO_REF:0000024, GO:0060687=GO_REF:0000024, GO:0045839=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0060174=GO_REF:0000024, GO:0060484=GO_REF:0000024, GO:0008286=Reactome:REACT_498, GO:0008284=PMID:8663044, GO:0008285=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0030324=GO_REF:0000024, GO:0007267=GO_REF:0000024, GO:0030282=GO_REF:0000024, GO:0048730=GO_REF:0000024, GO:0005737=PMID:17471512, GO:0035264=GO_REF:0000024, GO:0035265=GO_REF:0000024, GO:0045944=GO_REF:0000024, GO:0030855=GO_REF:0000024, GO:0022612=GO_REF:0000024, GO:0008201=GO_REF:0000037, GO:0005007=PMID:10830168, GO:0006915=GO_REF:0000037, GO:0002053=GO_REF:0000024, GO:0001525=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0031012=PMID:17959718, GO:0060365=GO_REF:0000019, GO:0016331=GO_REF:0000024, GO:0008589=GO_REF:0000024, GO:0003149=GO_REF:0000024, GO:0003148=GO_REF:0000024, GO:0060615=GO_REF:0000024, GO:0004713=PMID:1697263, GO:0043410=PMID:15629145, GO:0021769=GO_REF:0000024} P21802 Fibroblast growth factor receptor 2 protein 20120912 {GO:0005515=IPI, GO:0060045=ISS, GO:0090263=ISS, GO:0048705=TAS, GO:0009791=ISS, GO:0048701=IMP, GO:0021860=ISS, GO:0031069=ISS, GO:0060916=ISS, GO:0060915=ISS, GO:0046777=IDA, GO:0005794=IEA, GO:0042472=ISS, GO:0051150=ISS, GO:0009986=IDA, GO:0010518=IMP, GO:0018108=IDA, GO:0001701=ISS, GO:0060442=ISS, GO:0060348=ISS, GO:0045165=ISS, GO:0005887=IDA, GO:0045087=TAS, GO:0060349=ISS, GO:0060449=ISS, GO:0060445=ISS, GO:0060595=ISS, GO:0060529=ISS, GO:0021847=ISS, GO:0030177=ISS, GO:0005634=IDA, GO:0007528=IEA, GO:0060664=ISS, GO:0060667=ISS, GO:0048568=ISS, GO:0040014=ISS, GO:0042476=ISS, GO:0060523=ISS, GO:0060527=ISS, GO:0035604=ISS, GO:0048011=TAS, GO:0035603=ISS, GO:0035602=ISS, GO:0048015=TAS, GO:0048762=ISS, GO:0005576=IEA, GO:0048565=ISS, GO:0035607=ISS, GO:0048562=ISS, GO:0032808=ISS, GO:0045667=TAS, GO:0016020=NAS, GO:0040036=ISS, GO:0048557=ISS, GO:0060463=ISS, GO:0060512=ISS, GO:0016023=IEA, GO:0030901=ISS, GO:0048755=ISS, GO:0016021=NAS, GO:0061031=IEA, GO:0001657=ISS, GO:0033688=TAS, GO:0055010=ISS, GO:0070307=IEA, GO:0060670=ISS, GO:0007409=ISS, GO:0042803=IPI, GO:0042802=IPI, GO:0009880=ISS, GO:0048608=ISS, GO:0007173=TAS, GO:0060501=ISS, GO:0009887=ISS, GO:0051781=ISS, GO:0060601=ISS, GO:0070374=ISS, GO:0070372=ISS, GO:0005938=IDA, GO:0050679=ISS, GO:0048286=ISS, GO:0017134=IPI, GO:0010453=ISS, GO:0030916=ISS, GO:0048489=IEA, GO:0000122=ISS, GO:0060688=ISS, GO:0045787=ISS, GO:0060076=ISS, GO:0060687=ISS, GO:0045839=IEA, GO:0008543=TAS, GO:0060174=ISS, GO:0060484=ISS, GO:0008286=TAS, GO:0008284=IGI, GO:0008285=IEA, GO:0005886=IDA, GO:0030324=ISS, GO:0007267=ISS, GO:0030282=ISS, GO:0048730=ISS, GO:0005737=IDA, GO:0035264=ISS, GO:0035265=ISS, GO:0045944=ISS, GO:0030855=ISS, GO:0022612=ISS, GO:0008201=IEA, GO:0005007=IGI, GO:0006915=IEA, GO:0002053=ISS, GO:0001525=ISS, GO:0005524=IEA, GO:0031012=IDA, GO:0060365=IEA, GO:0016331=ISS, GO:0008589=ISS, GO:0003149=ISS, GO:0003148=ISS, GO:0060615=ISS, GO:0004713=NAS, GO:0043410=IMP, GO:0021769=ISS} angiogenesis, apoptotic process, axonogenesis, bone development, bone mineralization, bone morphogenesis, branch elongation involved in salivary gland morphogenesis, branching involved in labyrinthine layer morphogenesis, branching involved in prostate gland morphogenesis, branching involved in salivary gland morphogenesis, branching morphogenesis of a nerve, bud elongation involved in lung branching, cell fate commitment, cell-cell signaling, coronal suture morphogenesis, digestive tract development, embryonic cranial skeleton morphogenesis, embryonic digestive tract morphogenesis, embryonic organ development, embryonic organ morphogenesis, embryonic pattern specification, endodermal digestive tract morphogenesis, epidermal growth factor receptor signaling pathway, epidermis morphogenesis, epithelial cell differentiation, epithelial cell proliferation involved in salivary gland morphogenesis, fibroblast growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway involved in hemopoiesis, fibroblast growth factor receptor signaling pathway involved in mammary gland specification, fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow, fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development, fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow, gland morphogenesis, hair follicle morphogenesis, in utero embryonic development, innate immune response, inner ear morphogenesis, insulin receptor signaling pathway, lacrimal gland development, lateral sprouting from an epithelium, lens fiber cell development, limb bud formation, lung alveolus development, lung development, lung lobe morphogenesis, lung-associated mesenchyme development, mammary gland bud formation, membranous septum morphogenesis, mesenchymal cell differentiation, mesenchymal cell differentiation involved in lung development, mesenchymal cell proliferation involved in lung development, midbrain development, morphogenesis of embryonic epithelium, multicellular organism growth, negative regulation of cell proliferation, negative regulation of mitosis, negative regulation of transcription from RNA polymerase II promoter, neuromuscular junction development, neurotrophin TRK receptor signaling pathway, odontogenesis, orbitofrontal cortex development, organ growth, organ morphogenesis, otic vesicle formation, outflow tract septum morphogenesis, peptidyl-tyrosine phosphorylation, phosphatidylinositol-mediated signaling, positive regulation of ERK1 and ERK2 cascade, positive regulation of MAPK cascade, positive regulation of Wnt receptor signaling pathway, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of cardiac muscle cell proliferation, positive regulation of cell cycle, positive regulation of cell division, positive regulation of cell proliferation, positive regulation of epithelial cell proliferation, positive regulation of epithelial cell proliferation involved in lung morphogenesis, positive regulation of mesenchymal cell proliferation, positive regulation of phospholipase activity, positive regulation of transcription from RNA polymerase II promoter, post-embryonic development, prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis, prostate epithelial cord elongation, prostate gland morphogenesis, protein autophosphorylation, pyramidal neuron development, regulation of ERK1 and ERK2 cascade, regulation of branching involved in prostate gland morphogenesis, regulation of cell fate commitment, regulation of fibroblast growth factor receptor signaling pathway, regulation of morphogenesis of a branching structure, regulation of multicellular organism growth, regulation of osteoblast differentiation, regulation of osteoblast proliferation, regulation of smooth muscle cell differentiation, regulation of smoothened signaling pathway, reproductive structure development, skeletal system morphogenesis, squamous basal epithelial stem cell differentiation involved in prostate gland acinus development, synaptic vesicle transport, ureteric bud development, ventricular cardiac muscle tissue morphogenesis, ventricular zone neuroblast division Golgi apparatus, cell cortex, cell surface, cytoplasm, cytoplasmic membrane-bounded vesicle, excitatory synapse, extracellular matrix, extracellular region, integral to membrane, integral to plasma membrane, membrane, nucleus, plasma membrane ATP binding, fibroblast growth factor binding, fibroblast growth factor-activated receptor activity, heparin binding, identical protein binding, protein binding, protein homodimerization activity, protein tyrosine kinase activity Human FGFR3 BHF-UCL UniProtKB {GO:0005515=PMID:22939624, GO:0003416=PMID:15748888, GO:0070307=GO_REF:0000019, GO:0045597=GO_REF:0000019, GO:0090263=GO_REF:0000019, GO:0050680=GO_REF:0000019, GO:0035988=PMID:15748888, GO:0005764=GO_REF:0000019, GO:0048678=GO_REF:0000019, GO:0061144=GO_REF:0000019, GO:0046777=PMID:11294897, GO:0007173=Reactome:REACT_9417, GO:0043552=PMID:15748888, GO:0002062=PMID:15748888, GO:0000165=GO_REF:0000019, GO:0031398=GO_REF:0000019, GO:0070374=PMID:11294897, GO:0017134=PMID:8663044, GO:0010518=PMID:17561467, GO:0018108=PMID:11294897, GO:0000122=GO_REF:0000019, GO:0048546=GO_REF:0000019, GO:0048640=PMID:20582225, GO:0045839=GO_REF:0000019, GO:0072148=GO_REF:0000019, GO:0001501=PMID:8601314, GO:0001958=PMID:15748888, GO:0008543=Reactome:REACT_9510, GO:0005887=PMID:8663044, GO:0045087=Reactome:REACT_6802, GO:0060349=PMID:15748888, GO:0060385=GO_REF:0000019, GO:0009898=GO_REF:0000019, GO:0005925=PMID:15748888, GO:0008286=Reactome:REACT_498, GO:0048471=GO_REF:0000019, GO:0008284=PMID:8663044, GO:0005886=Reactome:REACT_147854, GO:0022010=GO_REF:0000019, GO:0005783=GO_REF:0000039, GO:0045879=GO_REF:0000019, GO:0002089=GO_REF:0000019, GO:0090102=GO_REF:0000019, GO:0035019=GO_REF:0000019, GO:0005007=PMID:8663044, GO:0048011=Reactome:REACT_11061, GO:0043066=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0060113=GO_REF:0000019, GO:0048015=Reactome:REACT_12464, GO:0042517=PMID:11294897, GO:0042511=PMID:17561467, GO:0006915=GO_REF:0000037, GO:0042981=PMID:17561467, GO:0070977=PMID:20582225, GO:0007259=PMID:10918587, GO:0005524=GO_REF:0000037, GO:0048712=GO_REF:0000019, GO:0001938=GO_REF:0000019, GO:0021762=GO_REF:0000019, GO:0016023=GO_REF:0000039, GO:0016021=GO_REF:0000002, GO:0004713=PMID:11294897, GO:0043410=PMID:11294897, GO:0002009=GO_REF:0000019, GO:0090080=GO_REF:0000019} P22607 Fibroblast growth factor receptor 3 protein 20101216 {GO:0005515=IPI, GO:0003416=TAS, GO:0070307=IEA, GO:0045597=IEA, GO:0090263=IEA, GO:0050680=IEA, GO:0035988=TAS, GO:0005764=IEA, GO:0048678=IEA, GO:0061144=IEA, GO:0046777=IDA, GO:0007173=TAS, GO:0043552=TAS, GO:0002062=TAS, GO:0000165=IEA, GO:0031398=IEA, GO:0070374=IMP, GO:0017134=IDA, GO:0010518=IMP, GO:0018108=IDA, GO:0000122=IEA, GO:0048546=IEA, GO:0048640=ISS, GO:0045839=IEA, GO:0072148=IEA, GO:0001501=TAS, GO:0001958=TAS, GO:0008543=TAS, GO:0005887=IDA, GO:0045087=TAS, GO:0060349=TAS, GO:0060385=IEA, GO:0009898=IEA, GO:0005925=TAS, GO:0008286=TAS, GO:0048471=IEA, GO:0008284=IGI, GO:0005886=TAS, GO:0022010=IEA, GO:0005783=IEA, GO:0045879=IEA, GO:0002089=IEA, GO:0090102=IEA, GO:0035019=IEA, GO:0005007=IMP, GO:0048011=TAS, GO:0043066=IEA, GO:0043065=IEA, GO:0060113=IEA, GO:0048015=TAS, GO:0042517=IMP, GO:0042511=IMP, GO:0006915=IEA, GO:0042981=IMP, GO:0070977=ISS, GO:0007259=TAS, GO:0005524=IEA, GO:0048712=IEA, GO:0001938=IEA, GO:0021762=IEA, GO:0016023=IEA, GO:0016021=IEA, GO:0004713=IDA, GO:0043410=IMP, GO:0002009=IEA, GO:0090080=IEA} JAK-STAT cascade, MAPK cascade, alveolar secondary septum development, apoptotic process, axonogenesis involved in innervation, bone maturation, bone morphogenesis, central nervous system myelination, chondrocyte differentiation, chondrocyte proliferation, cochlea development, digestive tract morphogenesis, endochondral bone growth, endochondral ossification, epidermal growth factor receptor signaling pathway, epithelial cell fate commitment, fibroblast growth factor receptor signaling pathway, innate immune response, inner ear receptor cell differentiation, insulin receptor signaling pathway, lens fiber cell development, lens morphogenesis in camera-type eye, morphogenesis of an epithelium, negative regulation of apoptotic process, negative regulation of astrocyte differentiation, negative regulation of developmental growth, negative regulation of epithelial cell proliferation, negative regulation of mitosis, negative regulation of smoothened signaling pathway, negative regulation of transcription from RNA polymerase II promoter, neurotrophin TRK receptor signaling pathway, peptidyl-tyrosine phosphorylation, phosphatidylinositol-mediated signaling, positive regulation of ERK1 and ERK2 cascade, positive regulation of MAPK cascade, positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway, positive regulation of apoptotic process, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of cell differentiation, positive regulation of cell proliferation, positive regulation of endothelial cell proliferation, positive regulation of phosphatidylinositol 3-kinase activity, positive regulation of phospholipase activity, positive regulation of protein ubiquitination, positive regulation of tyrosine phosphorylation of Stat1 protein, positive regulation of tyrosine phosphorylation of Stat3 protein, protein autophosphorylation, regulation of apoptotic process, response to axon injury, skeletal system development, somatic stem cell maintenance, substantia nigra development cytoplasmic membrane-bounded vesicle, endoplasmic reticulum, focal adhesion, integral to membrane, integral to plasma membrane, internal side of plasma membrane, lysosome, perinuclear region of cytoplasm, plasma membrane ATP binding, fibroblast growth factor binding, fibroblast growth factor-activated receptor activity, protein binding, protein tyrosine kinase activity Human UniProtKB:Q61851 FGFR4 HPA UniProtKB {GO:0008286=Reactome:REACT_498, GO:0008284=PMID:8663044, GO:2000188=GO_REF:0000024, GO:0005886=Reactome:REACT_147854, GO:0005783=PMID:20683963, GO:2000573=PMID:21653700, GO:0005634=GO_REF:0000052, GO:0001759=GO_REF:0000019, GO:0010715=PMID:20876804, GO:0061144=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0046777=PMID:20798051, GO:0007173=Reactome:REACT_9417, GO:0005911=PMID:20798051, GO:0070857=PMID:20683963, GO:0070374=PMID:21653700, GO:0008201=PMID:18480409, GO:0005007=PMID:10525310, GO:0048011=Reactome:REACT_11061, GO:0017134=PMID:10525310, GO:0048015=Reactome:REACT_12464, GO:0005730=GO_REF:0000052, GO:0055062=GO_REF:0000024, GO:0005576=GO_REF:0000039, GO:0018108=PMID:18480409, GO:0042593=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0045862=PMID:20798051, GO:0019216=GO_REF:0000024, GO:0048554=PMID:20798051, GO:0016477=PMID:20876804, GO:0008543=Reactome:REACT_9470, GO:0005887=PMID:20683963, GO:0045087=Reactome:REACT_6802, GO:0004713=Reactome:REACT_121299, GO:0016021=GO_REF:0000038, GO:0005768=GO_REF:0000039} P22455 Fibroblast growth factor receptor 4 protein 20101115 {GO:0008286=TAS, GO:0008284=IGI, GO:2000188=ISS, GO:0005886=TAS, GO:0005783=IDA, GO:2000573=IMP, GO:0005634=IDA, GO:0001759=IEA, GO:0010715=IMP, GO:0061144=IEA, GO:0005737=IDA, GO:0046777=IDA, GO:0007173=TAS, GO:0005911=IDA, GO:0070857=IMP, GO:0070374=IMP, GO:0008201=IDA, GO:0005007=IGI, GO:0048011=TAS, GO:0017134=IPI, GO:0048015=TAS, GO:0005730=IDA, GO:0055062=ISS, GO:0005576=IEA, GO:0018108=IDA, GO:0042593=ISS, GO:0005524=IEA, GO:0045862=IMP, GO:0019216=ISS, GO:0048554=IMP, GO:0016477=IMP, GO:0008543=TAS, GO:0005887=IDA, GO:0045087=TAS, GO:0004713=TAS, GO:0016021=IEA, GO:0005768=IEA} alveolar secondary septum development, cell migration, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, glucose homeostasis, innate immune response, insulin receptor signaling pathway, neurotrophin TRK receptor signaling pathway, organ induction, peptidyl-tyrosine phosphorylation, phosphate ion homeostasis, phosphatidylinositol-mediated signaling, positive regulation of DNA biosynthetic process, positive regulation of ERK1 and ERK2 cascade, positive regulation of cell proliferation, positive regulation of metalloenzyme activity, positive regulation of proteolysis, protein autophosphorylation, regulation of bile acid biosynthetic process, regulation of cholesterol homeostasis, regulation of extracellular matrix disassembly, regulation of lipid metabolic process cell-cell junction, cytoplasm, endoplasmic reticulum, endosome, extracellular region, integral to membrane, integral to plasma membrane, nucleolus, nucleus, plasma membrane ATP binding, fibroblast growth factor binding, fibroblast growth factor-activated receptor activity, heparin binding, protein tyrosine kinase activity Human FGFRL1 GOC UniProtKB {GO:0005007=PMID:12813049, GO:0001501=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0005886=PMID:12813049, GO:0008543=PMID:12813049, GO:0017134=GO_REF:0000019, GO:0060412=GO_REF:0000019, GO:0060539=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0003179=GO_REF:0000019, GO:0008201=PMID:12813049, GO:0001558=GO_REF:0000029} Q8N441 Fibroblast growth factor receptor-like 1 protein 20130413 {GO:0005007=IDA, GO:0001501=IEA, GO:0008285=IEA, GO:0005886=IDA, GO:0008543=IDA, GO:0017134=IEA, GO:0060412=IEA, GO:0060539=IEA, GO:0016021=IEA, GO:0003179=IEA, GO:0008201=IDA, GO:0001558=NAS} diaphragm development, fibroblast growth factor receptor signaling pathway, heart valve morphogenesis, negative regulation of cell proliferation, regulation of cell growth, skeletal system development, ventricular septum morphogenesis integral to membrane, plasma membrane fibroblast growth factor binding, fibroblast growth factor-activated receptor activity, heparin binding Human FGG BHF-UCL UniProtKB {GO:0051258=GO_REF:0000002, GO:0043499=PMID:6777381, GO:0005886=Reactome:REACT_726, GO:0005102=GO_REF:0000002, GO:0005577=GO_REF:0000002, GO:0030168=Reactome:REACT_798, GO:0072562=GO_REF:0000019, GO:0005576=Reactome:REACT_23931, GO:0005615=PMID:6777381, GO:0046872=GO_REF:0000037, GO:0051592=PMID:6777381, GO:0007165=GO_REF:0000002, GO:0007596=Reactome:REACT_2051, GO:0002576=Reactome:REACT_318, GO:0031091=PMID:6777381, GO:0031093=Reactome:REACT_21351, GO:0030674=GO_REF:0000002, GO:0005938=GO_REF:0000019, GO:0009897=PMID:6777381} P02679 Fibrinogen gamma chain protein 20081001 {GO:0051258=IEA, GO:0043499=IDA, GO:0005886=TAS, GO:0005102=IEA, GO:0005577=IEA, GO:0030168=TAS, GO:0072562=IEA, GO:0005576=TAS, GO:0005615=IDA, GO:0046872=IEA, GO:0051592=IDA, GO:0007165=IEA, GO:0007596=TAS, GO:0002576=TAS, GO:0031091=IDA, GO:0031093=TAS, GO:0030674=IEA, GO:0005938=IEA, GO:0009897=IDA} blood coagulation, platelet activation, platelet degranulation, protein polymerization, response to calcium ion, signal transduction blood microparticle, cell cortex, external side of plasma membrane, extracellular region, extracellular space, fibrinogen complex, plasma membrane, platelet alpha granule, platelet alpha granule lumen eukaryotic cell surface binding, metal ion binding, protein binding, bridging, receptor binding Human FGL1 PINC UniProtKB {GO:0035634=GO_REF:0000019, GO:0005577=PMID:8390249} Q08830 Fibrinogen-like protein 1 protein 20030904 {GO:0035634=IEA, GO:0005577=TAS} response to stilbenoid fibrinogen complex Human FGR ENSEMBL UniProtKB {GO:0005515=PMID:22939624, GO:0045859=GO_REF:0000019, GO:0005886=GO_REF:0000024, GO:0050830=GO_REF:0000019, GO:0008360=GO_REF:0000019, GO:0005743=GO_REF:0000039, GO:0050715=GO_REF:0000019, GO:0015629=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0050764=GO_REF:0000019, GO:0005758=GO_REF:0000039, GO:0046777=PMID:8327512, GO:0043552=PMID:10739672, GO:0005856=PMID:8603737, GO:0034987=GO_REF:0000019, GO:0030335=GO_REF:0000019, GO:0034988=PMID:8327512, GO:0019901=GO_REF:0000019, GO:0014068=PMID:10739672, GO:0018108=GO_REF:0000019, GO:0032587=GO_REF:0000019, GO:0009615=PMID:3003578, GO:0005524=GO_REF:0000002, GO:0043306=GO_REF:0000019, GO:0002768=PMID:8327512, GO:0007596=Reactome:REACT_604, GO:0007229=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0045088=GO_REF:0000019, GO:0006468=PMID:2995972, GO:0001784=GO_REF:0000019, GO:0004713=PMID:7519620, GO:0038096=Reactome:REACT_160123, GO:0004715=GO_REF:0000019} Q5TGY6 Tyrosine-protein kinase Fgr protein 20130413 {GO:0005515=IPI, GO:0045859=IEA, GO:0005886=ISS, GO:0050830=IEA, GO:0008360=IEA, GO:0005743=IEA, GO:0050715=IEA, GO:0015629=IEA, GO:0005829=IEA, GO:0050764=IEA, GO:0005758=IEA, GO:0046777=IDA, GO:0043552=IMP, GO:0005856=IDA, GO:0034987=IEA, GO:0030335=IEA, GO:0034988=IDA, GO:0019901=IEA, GO:0014068=IMP, GO:0018108=IEA, GO:0032587=IEA, GO:0009615=TAS, GO:0005524=IEA, GO:0043306=IEA, GO:0002768=TAS, GO:0007596=TAS, GO:0007229=IEA, GO:0045087=TAS, GO:0045088=IEA, GO:0006468=TAS, GO:0001784=IEA, GO:0004713=IDA, GO:0038096=TAS, GO:0004715=IEA} Fc-gamma receptor signaling pathway involved in phagocytosis, blood coagulation, defense response to Gram-positive bacterium, immune response-regulating cell surface receptor signaling pathway, innate immune response, integrin-mediated signaling pathway, peptidyl-tyrosine phosphorylation, positive regulation of cell migration, positive regulation of cytokine secretion, positive regulation of mast cell degranulation, positive regulation of phosphatidylinositol 3-kinase activity, positive regulation of phosphatidylinositol 3-kinase cascade, protein autophosphorylation, protein phosphorylation, regulation of cell shape, regulation of innate immune response, regulation of phagocytosis, regulation of protein kinase activity, response to virus actin cytoskeleton, cytoskeleton, cytosol, mitochondrial inner membrane, mitochondrial intermembrane space, plasma membrane, ruffle membrane ATP binding, Fc-gamma receptor I complex binding, immunoglobulin receptor binding, non-membrane spanning protein tyrosine kinase activity, phosphotyrosine binding, protein binding, protein kinase binding, protein tyrosine kinase activity Human Ensembl:ENSMUSP00000030693 FH Reactome UniProtKB {GO:0005739=PMID:8200987, GO:0005737=PMID:8200987, GO:0004333=Reactome:REACT_21360, GO:0006099=Reactome:REACT_1785, GO:0048873=GO_REF:0000019, GO:0006106=GO_REF:0000002, GO:0005759=Reactome:REACT_21360, GO:0044281=Reactome:REACT_111217, GO:0045239=GO_REF:0000002} P07954 Fumarate hydratase, mitochondrial protein 20091226 {GO:0005739=TAS, GO:0005737=TAS, GO:0004333=EXP, GO:0006099=TAS, GO:0048873=IEA, GO:0006106=IEA, GO:0005759=TAS, GO:0044281=TAS, GO:0045239=IEA} fumarate metabolic process, homeostasis of number of cells within a tissue, small molecule metabolic process, tricarboxylic acid cycle cytoplasm, mitochondrial matrix, mitochondrion, tricarboxylic acid cycle enzyme complex fumarate hydratase activity Human FHIT HPA UniProtKB {GO:0005515=PMID:18319262, GO:0006355=GO_REF:0000037, GO:0047710=PMID:9323207, GO:0032435=PMID:15313915, GO:0003824=PMID:8598045, GO:0006351=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0042802=PMID:16189514, GO:0005829=PMID:15313915, GO:0006260=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0000166=GO_REF:0000037, GO:0072332=PMID:15313915, GO:0016787=PMID:8794732, GO:0009117=PMID:8794732, GO:0031625=PMID:15313915, GO:0006163=PMID:9323207} P49789 Bis(5'-adenosyl)-triphosphatase protein 20100326 {GO:0005515=IPI, GO:0006355=IEA, GO:0047710=IDA, GO:0032435=IMP, GO:0003824=TAS, GO:0006351=IEA, GO:0043231=IDA, GO:0042802=IPI, GO:0005829=IDA, GO:0006260=IEA, GO:0005737=IDA, GO:0000166=IEA, GO:0072332=IMP, GO:0016787=IDA, GO:0009117=TAS, GO:0031625=IPI, GO:0006163=IDA} DNA replication, intrinsic apoptotic signaling pathway by p53 class mediator, negative regulation of proteasomal ubiquitin-dependent protein catabolic process, nucleotide metabolic process, purine nucleotide metabolic process, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, cytosol, intracellular membrane-bounded organelle bis(5'-adenosyl)-triphosphatase activity, catalytic activity, hydrolase activity, identical protein binding, nucleotide binding, protein binding, ubiquitin protein ligase binding Human FHL1 HPA UniProtKB {GO:0005515=PMID:19401155, GO:0030308=PMID:21702045, GO:0005886=GO_REF:0000052, GO:0043268=PMID:18281375, GO:0005634=PMID:21702045, GO:2000134=PMID:21702045, GO:0030154=GO_REF:0000037, GO:0005829=GO_REF:0000039, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0007517=PMID:7626119, GO:0010972=PMID:21702045, GO:0009887=PMID:7626119, GO:0008270=GO_REF:0000002, GO:0003254=PMID:18281375} Q5JXI8 Four and a half LIM domains protein 1 protein 20090616 {GO:0005515=IPI, GO:0030308=IDA, GO:0005886=IDA, GO:0043268=IDA, GO:0005634=IDA, GO:2000134=IDA, GO:0030154=IEA, GO:0005829=IEA, GO:0003674=ND, GO:0005737=IDA, GO:0007517=NAS, GO:0010972=IDA, GO:0009887=NAS, GO:0008270=IEA, GO:0003254=IDA} cell differentiation, muscle organ development, negative regulation of G1/S transition of mitotic cell cycle, negative regulation of G2/M transition of mitotic cell cycle, negative regulation of cell growth, organ morphogenesis, positive regulation of potassium ion transport, regulation of membrane depolarization cytoplasm, cytosol, nucleus, plasma membrane molecular_function, protein binding, zinc ion binding Human FHL2 InterPro UniProtKB {GO:0005515=PMID:19608030, GO:0030018=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0050681=PMID:15572661, GO:0044281=Reactome:REACT_111217, GO:0015629=GO_REF:0000052, GO:0042802=PMID:18255255, GO:0009725=PMID:17975004, GO:0044255=Reactome:REACT_22279, GO:0043066=PMID:15692560, GO:0006357=GO_REF:0000019, GO:0003713=PMID:15572661, GO:0000122=PMID:15692560, GO:0031430=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0001649=GO_REF:0000019, GO:0060347=GO_REF:0000019, GO:0055015=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_116040, GO:0055014=GO_REF:0000019, GO:0045893=PMID:15572661, GO:0045892=GO_REF:0000019, GO:0005925=GO_REF:0000052, GO:0030521=PMID:15572661, GO:0008134=PMID:15692560} Q5TM15 Splice variant of four and a half LIM domain protein 2 protein 20130413 {GO:0005515=IPI, GO:0030018=IEA, GO:0005634=IDA, GO:0050681=NAS, GO:0044281=TAS, GO:0015629=IDA, GO:0042802=IPI, GO:0009725=IMP, GO:0044255=TAS, GO:0043066=IDA, GO:0006357=IEA, GO:0003713=NAS, GO:0000122=IDA, GO:0031430=IEA, GO:0006351=IEA, GO:0001649=IEA, GO:0060347=IEA, GO:0055015=IEA, GO:0008270=IEA, GO:0005654=TAS, GO:0055014=IEA, GO:0045893=NAS, GO:0045892=IEA, GO:0005925=IDA, GO:0030521=NAS, GO:0008134=IPI} androgen receptor signaling pathway, atrial cardiac muscle cell development, cellular lipid metabolic process, heart trabecula formation, negative regulation of apoptotic process, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, osteoblast differentiation, positive regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, response to hormone stimulus, small molecule metabolic process, transcription, DNA-dependent, ventricular cardiac muscle cell development M band, Z disc, actin cytoskeleton, focal adhesion, nucleoplasm, nucleus androgen receptor binding, identical protein binding, protein binding, transcription coactivator activity, transcription factor binding, zinc ion binding Human InterPro:IPR001781 FHL3 PINC UniProtKB {GO:0030018=GO_REF:0000019, GO:0001725=GO_REF:0000019, GO:0007517=PMID:10049693, GO:0030036=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0003779=GO_REF:0000019, GO:0008270=GO_REF:0000002} Q13643 Four and a half LIM domains protein 3 protein 20030904 {GO:0030018=IEA, GO:0001725=IEA, GO:0007517=TAS, GO:0030036=IEA, GO:0005634=IEA, GO:0003779=IEA, GO:0008270=IEA} actin cytoskeleton organization, muscle organ development Z disc, nucleus, stress fiber actin binding, zinc ion binding Human FHL5 UniProtKB UniProtKB {GO:0045944=GO_REF:0000019, GO:0003713=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002} Q5TD97 Four and a half LIM domains protein 5 protein 20130413 {GO:0045944=IEA, GO:0003713=IEA, GO:0005634=IEA, GO:0008270=IEA} positive regulation of transcription from RNA polymerase II promoter nucleus transcription coactivator activity, zinc ion binding Human UniProtKB-SubCell:SL-0191 FHOD1 HPA UniProtKB {GO:0005515=PMID:15095401, GO:0001725=PMID:15095401, GO:0005737=GO_REF:0000052, GO:0032059=GO_REF:0000039, GO:0030036=GO_REF:0000002, GO:0045944=PMID:15095401, GO:0051496=PMID:15095401, GO:0005634=PMID:15095401, GO:0003779=GO_REF:0000037} Q9Y613 FH1/FH2 domain-containing protein 1 protein 20101115 {GO:0005515=IPI, GO:0001725=IDA, GO:0005737=IDA, GO:0032059=IEA, GO:0030036=IEA, GO:0045944=IDA, GO:0051496=IDA, GO:0005634=IDA, GO:0003779=IEA} actin cytoskeleton organization, positive regulation of stress fiber assembly, positive regulation of transcription from RNA polymerase II promoter bleb, cytoplasm, nucleus, stress fiber actin binding, protein binding Human FHOD3 HPA UniProtKB {GO:0005515=PMID:21149568, GO:0005737=GO_REF:0000052, GO:0030018=GO_REF:0000039, GO:0030036=GO_REF:0000002, GO:0030837=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0045214=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0003779=GO_REF:0000037, GO:0005856=GO_REF:0000039} Q2V2M9 FH1/FH2 domain-containing protein 3 protein 20110516 {GO:0005515=IPI, GO:0005737=IDA, GO:0030018=IEA, GO:0030036=IEA, GO:0030837=IEA, GO:0005730=IDA, GO:0045214=IEA, GO:0005634=IDA, GO:0003779=IEA, GO:0005856=IEA} actin cytoskeleton organization, negative regulation of actin filament polymerization, sarcomere organization Z disc, cytoplasm, cytoskeleton, nucleolus, nucleus actin binding, protein binding Human FIBCD1 UniProtKB UniProtKB {GO:0008061=PMID:19710473, GO:0016020=PMID:19710473, GO:0016021=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q8N539 Fibrinogen C domain-containing protein 1 protein 20100126 {GO:0008061=IDA, GO:0016020=IDA, GO:0016021=IEA, GO:0046872=IEA} integral to membrane, membrane chitin binding, metal ion binding Human FIBP MGI UniProtKB {GO:0005739=PMID:9806903, GO:0016020=PMID:9806903, GO:0008543=PMID:9806903, GO:0017134=PMID:9806903, GO:0005634=PMID:9806903, GO:0012505=GO_REF:0000039} O43427 Acidic fibroblast growth factor intracellular-binding protein protein 20091019 {GO:0005739=TAS, GO:0016020=IDA, GO:0008543=TAS, GO:0017134=IPI, GO:0005634=IDA, GO:0012505=IEA} fibroblast growth factor receptor signaling pathway endomembrane system, membrane, mitochondrion, nucleus fibroblast growth factor binding Human UniProtKB:P05230 FICD UniProtKB UniProtKB {GO:0018117=PMID:22266942, GO:0034259=PMID:19362538, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0070733=PMID:22266942} Q9BVA6 Adenosine monophosphate-protein transferase FICD protein 20120503 {GO:0018117=IDA, GO:0034259=TAS, GO:0016021=IEA, GO:0005524=IEA, GO:0070733=IDA} negative regulation of Rho GTPase activity, protein adenylylation integral to membrane ATP binding, protein adenylyltransferase activity Human FIG4 GOC UniProtKB {GO:0005515=PMID:17556371, GO:0008219=GO_REF:0000037, GO:0006661=Reactome:REACT_120918, GO:0043813=Reactome:REACT_121182, GO:0036092=Reactome:REACT_121182, GO:0043812=GO_REF:0000019, GO:0046488=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0034593=GO_REF:0000019, GO:0032288=GO_REF:0000019, GO:0042578=GO_REF:0000002, GO:0000139=Reactome:REACT_121149, GO:0048666=GO_REF:0000019, GO:0031901=Reactome:REACT_121095, GO:0004438=GO_REF:0000019, GO:0031902=Reactome:REACT_121182, GO:0010976=GO_REF:0000019, GO:0043473=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0007033=GO_REF:0000019, GO:0006644=Reactome:REACT_121175, GO:0010008=PMID:17556371, GO:0031642=GO_REF:0000019} Q92562 Polyphosphoinositide phosphatase protein 20130413 {GO:0005515=IPI, GO:0008219=IEA, GO:0006661=TAS, GO:0043813=TAS, GO:0036092=TAS, GO:0043812=IEA, GO:0046488=IEA, GO:0044281=TAS, GO:0034593=IEA, GO:0032288=IEA, GO:0042578=IEA, GO:0000139=TAS, GO:0048666=IEA, GO:0031901=TAS, GO:0004438=IEA, GO:0031902=TAS, GO:0010976=IEA, GO:0043473=IEA, GO:0007626=IEA, GO:0007033=IEA, GO:0006644=TAS, GO:0010008=IDA, GO:0031642=IEA} cell death, locomotory behavior, myelin assembly, negative regulation of myelination, neuron development, phosphatidylinositol biosynthetic process, phosphatidylinositol metabolic process, phosphatidylinositol-3-phosphate biosynthetic process, phospholipid metabolic process, pigmentation, positive regulation of neuron projection development, small molecule metabolic process, vacuole organization Golgi membrane, early endosome membrane, endosome membrane, late endosome membrane phosphatidylinositol bisphosphate phosphatase activity, phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity, phosphatidylinositol-3-phosphatase activity, phosphatidylinositol-4-phosphate phosphatase activity, phosphoric ester hydrolase activity, protein binding Human FIGF GOC UniProtKB {GO:0048010=Reactome:REACT_12529, GO:0008284=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_21351, GO:0060754=PMID:19275959, GO:0001525=GO_REF:0000037, GO:0005161=PMID:9479493, GO:0005615=GO_REF:0000019, GO:0042056=PMID:19275959, GO:0030154=GO_REF:0000037, GO:0042803=GO_REF:0000019, GO:0050918=PMID:19275959, GO:0050930=PMID:19275959, GO:0016020=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0043185=GO_REF:0000019, GO:0031093=Reactome:REACT_21351, GO:0051781=GO_REF:0000037, GO:0005172=PMID:9435229, GO:0008083=GO_REF:0000019} O43915 Vascular endothelial growth factor D protein 20130413 {GO:0048010=TAS, GO:0008284=IEA, GO:0008283=IEA, GO:0030168=TAS, GO:0005576=TAS, GO:0060754=IDA, GO:0001525=IEA, GO:0005161=TAS, GO:0005615=IEA, GO:0042056=IDA, GO:0030154=IEA, GO:0042803=IEA, GO:0050918=IDA, GO:0050930=IDA, GO:0016020=IEA, GO:0007596=TAS, GO:0002576=TAS, GO:0043185=IEA, GO:0031093=TAS, GO:0051781=IEA, GO:0005172=IPI, GO:0008083=IEA} angiogenesis, blood coagulation, cell differentiation, cell proliferation, induction of positive chemotaxis, platelet activation, platelet degranulation, positive chemotaxis, positive regulation of cell division, positive regulation of cell proliferation, positive regulation of mast cell chemotaxis, vascular endothelial growth factor receptor signaling pathway extracellular region, extracellular space, membrane, platelet alpha granule lumen chemoattractant activity, growth factor activity, platelet-derived growth factor receptor binding, protein homodimerization activity, vascular endothelial growth factor receptor 3 binding, vascular endothelial growth factor receptor binding Human FIGN UniProtKB UniProtKB {GO:0017111=GO_REF:0000002, GO:0008022=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0016363=GO_REF:0000024} Q5HY92 Fidgetin protein 20090922 {GO:0017111=IEA, GO:0008022=IEA, GO:0005524=IEA, GO:0016363=ISS} nuclear matrix ATP binding, nucleoside-triphosphatase activity, protein C-terminus binding Human UniProtKB:Q9ERZ6 FIGNL1 UniProtKB UniProtKB {GO:0017111=GO_REF:0000002, GO:0043066=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0046034=GO_REF:0000024, GO:0000287=GO_REF:0000024, GO:0016787=GO_REF:0000024, GO:0033687=GO_REF:0000024, GO:0051726=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0001649=GO_REF:0000024} Q6PIW4 Fidgetin-like protein 1 protein 20110302 {GO:0017111=IEA, GO:0043066=ISS, GO:0005737=ISS, GO:0046034=ISS, GO:0000287=ISS, GO:0016787=ISS, GO:0033687=ISS, GO:0051726=ISS, GO:0005634=ISS, GO:0005524=IEA, GO:0001649=ISS} ATP metabolic process, negative regulation of apoptotic process, osteoblast differentiation, osteoblast proliferation, regulation of cell cycle cytoplasm, nucleus ATP binding, hydrolase activity, magnesium ion binding, nucleoside-triphosphatase activity Human UniProtKB:Q8BPY9 FILIP1 null null {} null null null null {} null null null FILIP1L UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000039, GO:0016020=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0016459=GO_REF:0000029} Q4L180 Filamin A-interacting protein 1-like protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0005737=IEA, GO:0016020=IEA, GO:0005634=IEA, GO:0016459=NAS} biological_process cytoplasm, membrane, myosin complex, nucleus molecular_function Human FIP1L1 HPA UniProtKB {GO:0006397=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005847=GO_REF:0000019, GO:0005634=GO_REF:0000052} Q6UN15 Pre-mRNA 3'-end-processing factor FIP1 protein 20111111 {GO:0006397=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005847=IEA, GO:0005634=IDA} mRNA processing mRNA cleavage and polyadenylation specificity factor complex, nucleolus, nucleus RNA binding NOT Human FIS1 HPA UniProtKB {GO:0005515=PMID:21183955, GO:0035584=PMID:21183955, GO:0010821=PMID:21149567, GO:0000266=PMID:18845145, GO:0000422=PMID:18515060, GO:0005102=PMID:20178365, GO:0006915=PMID:16118244, GO:0001836=PMID:19864424, GO:0043653=PMID:17545159, GO:0007204=PMID:21183955, GO:0043280=PMID:21183955, GO:0005739=GO_REF:0000052, GO:0043234=PMID:20826455, GO:0070584=PMID:21149567, GO:0051561=PMID:21183955, GO:0051260=PMID:18845145, GO:0031307=PMID:18845145, GO:0005779=PMID:17408615, GO:0032471=PMID:21183955, GO:0005777=PMID:14561759, GO:0016559=PMID:20826455} Q9Y3D6 Mitochondrial fission 1 protein protein 20090616 {GO:0005515=IPI, GO:0035584=IMP, GO:0010821=IMP, GO:0000266=IDA, GO:0000422=IDA, GO:0005102=IPI, GO:0006915=IDA, GO:0001836=IMP, GO:0043653=IDA, GO:0007204=IMP, GO:0043280=IMP, GO:0005739=IDA, GO:0043234=IDA, GO:0070584=IMP, GO:0051561=IMP, GO:0051260=IMP, GO:0031307=NAS, GO:0005779=IDA, GO:0032471=IMP, GO:0005777=ISS, GO:0016559=IMP} apoptotic process, calcium-mediated signaling using intracellular calcium source, elevation of cytosolic calcium ion concentration, elevation of mitochondrial calcium ion concentration, mitochondrial fission, mitochondrial fragmentation involved in apoptotic process, mitochondrion degradation, mitochondrion morphogenesis, peroxisome fission, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, protein homooligomerization, reduction of endoplasmic reticulum calcium ion concentration, regulation of mitochondrion organization, release of cytochrome c from mitochondria integral to mitochondrial outer membrane, integral to peroxisomal membrane, mitochondrion, peroxisome, protein complex protein binding, receptor binding Human FITM1 BHF-UCL UniProtKB {GO:0003674=GO_REF:0000015, GO:0010890=PMID:18160536, GO:0005789=PMID:18160536, GO:0030176=GO_REF:0000019, GO:0034389=PMID:18160536} A5D6W6 Fat storage-inducing transmembrane protein 1 protein 20100303 {GO:0003674=ND, GO:0010890=ISS, GO:0005789=ISS, GO:0030176=IEA, GO:0034389=ISS} lipid particle organization, positive regulation of sequestering of triglyceride endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane molecular_function Human FITM2 BHF-UCL UniProtKB {GO:0005739=GO_REF:0000019, GO:0003674=GO_REF:0000015, GO:0010890=PMID:18160536, GO:0022604=PMID:21834987, GO:0007010=PMID:21834987, GO:0005789=PMID:18160536, GO:0030176=GO_REF:0000024, GO:0035356=PMID:18160536, GO:0010866=PMID:18160536, GO:0034389=PMID:18160536} Q8N6M3 Fat storage-inducing transmembrane protein 2 protein 20100303 {GO:0005739=IEA, GO:0003674=ND, GO:0010890=ISS, GO:0022604=IMP, GO:0007010=IMP, GO:0005789=ISS, GO:0030176=ISS, GO:0035356=ISS, GO:0010866=ISS, GO:0034389=ISS} cellular triglyceride homeostasis, cytoskeleton organization, lipid particle organization, positive regulation of sequestering of triglyceride, regulation of cell morphogenesis, regulation of triglyceride biosynthetic process endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane, mitochondrion molecular_function Human FIZ1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000024, GO:0006355=GO_REF:0000037, GO:0019901=GO_REF:0000024, GO:0005102=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q96SL8 Flt3-interacting zinc finger protein 1 protein 20050413 {GO:0005737=ISS, GO:0006355=IEA, GO:0019901=ISS, GO:0005102=ISS, GO:0005634=ISS, GO:0008270=IEA, GO:0003676=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus nucleic acid binding, protein kinase binding, receptor binding, zinc ion binding Human UniProtKB:Q9WTJ4 FJX1 ENSEMBL UniProtKB {GO:0005615=GO_REF:0000019} Q86VR8 Four-jointed box protein 1 protein 20130413 {GO:0005615=IEA} extracellular space Human Ensembl:ENSMUSP00000097270 FKBP10 InterPro UniProtKB {GO:0000413=GO_REF:0000033, GO:0016020=GO_REF:0000033, GO:0006457=GO_REF:0000002, GO:0018208=GO_REF:0000033, GO:0005509=GO_REF:0000002, GO:0003755=GO_REF:0000033, GO:0005528=GO_REF:0000033, GO:0005788=GO_REF:0000039} Q9H6J3 Peptidyl-prolyl cis-trans isomerase FKBP10 protein 20130413 {GO:0000413=IBA, GO:0016020=IBA, GO:0006457=IEA, GO:0018208=IBA, GO:0005509=IEA, GO:0003755=IBA, GO:0005528=IBA, GO:0005788=IEA} peptidyl-proline modification, protein folding, protein peptidyl-prolyl isomerization endoplasmic reticulum lumen, membrane FK506 binding, calcium ion binding, peptidyl-prolyl cis-trans isomerase activity Human InterPro:IPR001179 FKBP11 GOC UniProtKB {GO:0000413=GO_REF:0000033, GO:0016020=GO_REF:0000033, GO:0006457=GO_REF:0000037, GO:0018208=GO_REF:0000033, GO:0003755=GO_REF:0000033, GO:0005528=GO_REF:0000033, GO:0016021=GO_REF:0000037} Q9NYL4 Peptidyl-prolyl cis-trans isomerase FKBP11 protein 20130413 {GO:0000413=IBA, GO:0016020=IBA, GO:0006457=IEA, GO:0018208=IBA, GO:0003755=IBA, GO:0005528=IBA, GO:0016021=IEA} peptidyl-proline modification, protein folding, protein peptidyl-prolyl isomerization integral to membrane, membrane FK506 binding, peptidyl-prolyl cis-trans isomerase activity Human PANTHER:PTN000054102 FKBP14 GOC UniProtKB {GO:0000413=GO_REF:0000033, GO:0016020=GO_REF:0000033, GO:0006457=GO_REF:0000037, GO:0018208=GO_REF:0000033, GO:0005509=GO_REF:0000002, GO:0003755=GO_REF:0000033, GO:0005788=Reactome:REACT_115587, GO:0005528=GO_REF:0000033, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0030968=Reactome:REACT_18356} Q9NWM8 Peptidyl-prolyl cis-trans isomerase FKBP14 protein 20130413 {GO:0000413=IBA, GO:0016020=IBA, GO:0006457=IEA, GO:0018208=IBA, GO:0005509=IEA, GO:0003755=IBA, GO:0005788=TAS, GO:0005528=IBA, GO:0006987=TAS, GO:0044267=TAS, GO:0030968=TAS} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, peptidyl-proline modification, protein folding, protein peptidyl-prolyl isomerization endoplasmic reticulum lumen, membrane FK506 binding, calcium ion binding, peptidyl-prolyl cis-trans isomerase activity Human PANTHER:PTN000054102 FKBP15 UniProtKB UniProtKB {GO:0030424=GO_REF:0000039, GO:0006457=GO_REF:0000002, GO:0010923=PMID:19389623, GO:0005884=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0005769=GO_REF:0000039, GO:0030426=GO_REF:0000019, GO:0006897=GO_REF:0000037} Q5T1M5 FK506-binding protein 15 protein 20111103 {GO:0030424=IEA, GO:0006457=IEA, GO:0010923=IDA, GO:0005884=IEA, GO:0003779=IEA, GO:0005769=IEA, GO:0030426=IEA, GO:0006897=IEA} endocytosis, negative regulation of phosphatase activity, protein folding actin filament, axon, early endosome, growth cone actin binding Human FKBP1A UniProtKB UniProtKB {GO:0000413=PMID:2477715, GO:0005515=PMID:10358090, GO:0030424=GO_REF:0000033, GO:0055010=GO_REF:0000024, GO:0046332=PMID:16720724, GO:0022417=PMID:11322937, GO:0032092=PMID:18346205, GO:0005829=PMID:1701173, GO:0042026=PMID:11322937, GO:0005737=PMID:12443530, GO:0006458=PMID:11322937, GO:0006457=GO_REF:0000038, GO:0048185=PMID:16720724, GO:0060314=PMID:7592869, GO:0060315=PMID:12443530, GO:0031398=PMID:16720724, GO:0005024=PMID:11322937, GO:0007179=Reactome:REACT_120850, GO:0043206=PMID:18346205, GO:0004871=PMID:12761501, GO:0051280=PMID:12443530, GO:0043123=PMID:12761501, GO:0014802=PMID:1374404, GO:0003755=GO_REF:0000038, GO:0005528=PMID:17962721, GO:0033017=GO_REF:0000033, GO:0005160=PMID:7518616, GO:0032925=PMID:16720724, GO:0034205=PMID:18346205, GO:0005527=PMID:17962721, GO:0060347=GO_REF:0000024, GO:0007183=PMID:16720724, GO:0003007=GO_REF:0000024, GO:0042110=PMID:1696686, GO:0016020=PMID:12443530, GO:0034713=PMID:7518616, GO:0019855=PMID:12443530, GO:0018208=GO_REF:0000033, GO:0032513=PMID:7592869, GO:0050776=PMID:2477715, GO:0005219=PMID:11322937} Q5W0X3 Peptidyl-prolyl cis-trans isomerase protein 20130413 {GO:0000413=IDA, GO:0005515=IPI, GO:0030424=IBA, GO:0055010=ISS, GO:0046332=IPI, GO:0022417=TAS, GO:0032092=IDA, GO:0005829=IDA, GO:0042026=TAS, GO:0005737=IDA, GO:0006458=TAS, GO:0006457=IEA, GO:0048185=IPI, GO:0060314=IDA, GO:0060315=IDA, GO:0031398=IDA, GO:0005024=TAS, GO:0007179=TAS, GO:0043206=IDA, GO:0004871=IMP, GO:0051280=IDA, GO:0043123=IMP, GO:0014802=ISS, GO:0003755=IEA, GO:0005528=NAS, GO:0033017=IBA, GO:0005160=ISS, GO:0032925=IDA, GO:0034205=IDA, GO:0005527=NAS, GO:0060347=ISS, GO:0007183=IDA, GO:0003007=ISS, GO:0042110=NAS, GO:0016020=IDA, GO:0034713=ISS, GO:0019855=IDA, GO:0018208=IBA, GO:0032513=IDA, GO:0050776=IMP, GO:0005219=TAS} 'de novo' protein folding, SMAD protein complex assembly, T cell activation, beta-amyloid formation, extracellular fibril organization, heart morphogenesis, heart trabecula formation, negative regulation of protein phosphatase type 2B activity, negative regulation of release of sequestered calcium ion into cytosol, negative regulation of ryanodine-sensitive calcium-release channel activity, peptidyl-proline modification, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of protein binding, positive regulation of protein ubiquitination, protein folding, protein maturation by protein folding, protein peptidyl-prolyl isomerization, protein refolding, regulation of activin receptor signaling pathway, regulation of immune response, regulation of ryanodine-sensitive calcium-release channel activity, transforming growth factor beta receptor signaling pathway, ventricular cardiac muscle tissue morphogenesis axon, cytoplasm, cytosol, membrane, sarcoplasmic reticulum membrane, terminal cisterna FK506 binding, SMAD binding, activin binding, calcium channel inhibitor activity, macrolide binding, peptidyl-prolyl cis-trans isomerase activity, protein binding, ryanodine-sensitive calcium-release channel activity, signal transducer activity, transforming growth factor beta receptor binding, transforming growth factor beta-activated receptor activity, type I transforming growth factor beta receptor binding Human UniProtKB-KW:KW-0697 FKBP1B GOC UniProtKB {GO:0000413=PMID:7592869, GO:0005515=PMID:7592869, GO:0042542=GO_REF:0000019, GO:0019227=GO_REF:0000019, GO:0022417=PMID:11322937, GO:0005829=PMID:7592869, GO:0006939=GO_REF:0000019, GO:0042026=PMID:11322937, GO:0005737=PMID:12443530, GO:0030551=GO_REF:0000019, GO:0006936=GO_REF:0000029, GO:0006458=PMID:11322937, GO:0042098=GO_REF:0000019, GO:0006457=GO_REF:0000038, GO:0060314=PMID:7592869, GO:0033197=GO_REF:0000019, GO:0051280=PMID:12443530, GO:0010459=GO_REF:0000024, GO:0003755=PMID:7592869, GO:0005102=PMID:10830164, GO:0033017=GO_REF:0000033, GO:0010881=GO_REF:0000024, GO:0005528=PMID:7592869, GO:0014808=GO_REF:0000019, GO:1901385=PMID:17921453, GO:0034704=PMID:10830164, GO:0009749=GO_REF:0000019, GO:0044325=GO_REF:0000019, GO:0016020=PMID:12443530, GO:0018208=GO_REF:0000033, GO:0032513=PMID:7592869, GO:0051775=PMID:19226252, GO:0030073=GO_REF:0000019, GO:0061179=GO_REF:0000019, GO:0005219=PMID:11322937} P68106 Peptidyl-prolyl cis-trans isomerase FKBP1B protein 20130413 {GO:0000413=IDA, GO:0005515=IPI, GO:0042542=IEA, GO:0019227=IEA, GO:0022417=TAS, GO:0005829=IC, GO:0006939=IEA, GO:0042026=TAS, GO:0005737=IDA, GO:0030551=IEA, GO:0006936=NAS, GO:0006458=TAS, GO:0042098=IEA, GO:0006457=IEA, GO:0060314=IMP, GO:0033197=IEA, GO:0051280=IDA, GO:0010459=ISS, GO:0003755=IDA, GO:0005102=IPI, GO:0033017=IBA, GO:0010881=ISS, GO:0005528=IDA, GO:0014808=IEA, GO:1901385=IDA, GO:0034704=IDA, GO:0009749=IEA, GO:0044325=IEA, GO:0016020=IDA, GO:0018208=IBA, GO:0032513=IDA, GO:0051775=IDA, GO:0030073=IEA, GO:0061179=IEA, GO:0005219=TAS} 'de novo' protein folding, T cell proliferation, insulin secretion, muscle contraction, negative regulation of heart rate, negative regulation of insulin secretion involved in cellular response to glucose stimulus, negative regulation of protein phosphatase type 2B activity, negative regulation of release of sequestered calcium ion into cytosol, neuronal action potential propagation, peptidyl-proline modification, protein folding, protein maturation by protein folding, protein peptidyl-prolyl isomerization, protein refolding, regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion, regulation of ryanodine-sensitive calcium-release channel activity, regulation of voltage-gated calcium channel activity, release of sequestered calcium ion into cytosol by sarcoplasmic reticulum, response to glucose stimulus, response to hydrogen peroxide, response to redox state, response to vitamin E, smooth muscle contraction calcium channel complex, cytoplasm, cytosol, membrane, sarcoplasmic reticulum membrane FK506 binding, cyclic nucleotide binding, ion channel binding, peptidyl-prolyl cis-trans isomerase activity, protein binding, receptor binding, ryanodine-sensitive calcium-release channel activity Human FKBP2 GOC UniProtKB {GO:0000413=GO_REF:0000033, GO:0005515=PMID:16713569, GO:0016020=GO_REF:0000033, GO:0005783=PMID:1713687, GO:0006457=GO_REF:0000037, GO:0018208=GO_REF:0000033, GO:0005789=GO_REF:0000039, GO:0003755=GO_REF:0000033, GO:0005528=GO_REF:0000033} P26885 Peptidyl-prolyl cis-trans isomerase FKBP2 protein 20130413 {GO:0000413=IBA, GO:0005515=IPI, GO:0016020=IBA, GO:0005783=TAS, GO:0006457=IEA, GO:0018208=IBA, GO:0005789=IEA, GO:0003755=IBA, GO:0005528=IBA} peptidyl-proline modification, protein folding, protein peptidyl-prolyl isomerization endoplasmic reticulum, endoplasmic reticulum membrane, membrane FK506 binding, peptidyl-prolyl cis-trans isomerase activity, protein binding Human PANTHER:PTN000054102 FKBP3 GOC UniProtKB {GO:0000413=GO_REF:0000033, GO:0016020=GO_REF:0000033, GO:0006457=GO_REF:0000037, GO:0018208=GO_REF:0000033, GO:0003755=GO_REF:0000033, GO:0005528=GO_REF:0000033, GO:0004872=PMID:1374240, GO:0005634=GO_REF:0000033} Q00688 Peptidyl-prolyl cis-trans isomerase FKBP3 protein 20130413 {GO:0000413=IBA, GO:0016020=IBA, GO:0006457=IEA, GO:0018208=IBA, GO:0003755=IBA, GO:0005528=IBA, GO:0004872=TAS, GO:0005634=IBA} peptidyl-proline modification, protein folding, protein peptidyl-prolyl isomerization membrane, nucleus FK506 binding, peptidyl-prolyl cis-trans isomerase activity, receptor activity Human PANTHER:PTN000054102 FKBP4 GOC UniProtKB {GO:0000413=PMID:11350175, GO:0005515=PMID:12604780, GO:0051219=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0046661=GO_REF:0000019, GO:0031503=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0035259=GO_REF:0000019, GO:0005829=GO_REF:0000024, GO:0005622=GO_REF:0000029, GO:0005739=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0006457=PMID:1279700, GO:0031072=PMID:9660753, GO:0043025=GO_REF:0000019, GO:0030850=GO_REF:0000019, GO:0030674=PMID:2378870, GO:0031115=GO_REF:0000019, GO:0032767=GO_REF:0000019, GO:0031111=GO_REF:0000024, GO:0007566=GO_REF:0000019, GO:0005874=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0003755=PMID:11350175, GO:0048156=GO_REF:0000019, GO:0005528=PMID:1376003, GO:0005525=GO_REF:0000019, GO:0044295=GO_REF:0000024, GO:0005524=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0061077=PMID:11350175, GO:0016020=GO_REF:0000033, GO:0018208=GO_REF:0000033, GO:0010977=GO_REF:0000024, GO:0006463=GO_REF:0000019, GO:0030521=GO_REF:0000019, GO:0006825=GO_REF:0000019} Q02790 Peptidyl-prolyl cis-trans isomerase FKBP4 protein 20130413 {GO:0000413=IDA, GO:0005515=IPI, GO:0051219=IEA, GO:0048471=IEA, GO:0046661=IEA, GO:0031503=IEA, GO:0005634=IDA, GO:0035259=IEA, GO:0005829=ISS, GO:0005622=NAS, GO:0005739=IEA, GO:0005737=IDA, GO:0006457=TAS, GO:0031072=IPI, GO:0043025=IEA, GO:0030850=IEA, GO:0030674=TAS, GO:0031115=IEA, GO:0032767=IEA, GO:0031111=ISS, GO:0007566=IEA, GO:0005874=IEA, GO:0005730=IDA, GO:0003755=IDA, GO:0048156=IEA, GO:0005528=TAS, GO:0005525=IEA, GO:0044295=ISS, GO:0005524=IEA, GO:0043234=IEA, GO:0061077=IDA, GO:0016020=IBA, GO:0018208=IBA, GO:0010977=ISS, GO:0006463=IEA, GO:0030521=IEA, GO:0006825=IEA} androgen receptor signaling pathway, chaperone-mediated protein folding, copper ion transport, embryo implantation, male sex differentiation, negative regulation of microtubule polymerization, negative regulation of microtubule polymerization or depolymerization, negative regulation of neuron projection development, peptidyl-proline modification, prostate gland development, protein complex localization, protein folding, protein peptidyl-prolyl isomerization, steroid hormone receptor complex assembly axonal growth cone, cytoplasm, cytosol, intracellular, membrane, microtubule, mitochondrion, neuronal cell body, nucleolus, nucleus, perinuclear region of cytoplasm, protein complex ATP binding, FK506 binding, GTP binding, copper-dependent protein binding, glucocorticoid receptor binding, heat shock protein binding, peptidyl-prolyl cis-trans isomerase activity, phosphoprotein binding, protein binding, protein binding, bridging, tau protein binding Human FKBP5 GOC UniProtKB {GO:0000413=PMID:11350175, GO:0005737=GO_REF:0000039, GO:0061077=PMID:11350175, GO:0016020=GO_REF:0000033, GO:0006457=PMID:9001212, GO:0031072=PMID:9660753, GO:0018208=GO_REF:0000033, GO:0005730=GO_REF:0000052, GO:0003755=PMID:11350175, GO:0005528=GO_REF:0000033, GO:0005634=GO_REF:0000052} Q13451 Peptidyl-prolyl cis-trans isomerase FKBP5 protein 20130413 {GO:0000413=IDA, GO:0005737=IEA, GO:0061077=IDA, GO:0016020=IBA, GO:0006457=TAS, GO:0031072=IPI, GO:0018208=IBA, GO:0005730=IDA, GO:0003755=IDA, GO:0005528=IBA, GO:0005634=IDA} chaperone-mediated protein folding, peptidyl-proline modification, protein folding, protein peptidyl-prolyl isomerization cytoplasm, membrane, nucleolus, nucleus FK506 binding, heat shock protein binding, peptidyl-prolyl cis-trans isomerase activity Human FKBP6 RefGenome UniProtKB {GO:0016020=GO_REF:0000033, GO:0000239=GO_REF:0000019, GO:0006457=GO_REF:0000037, GO:0018208=GO_REF:0000033, GO:0003755=GO_REF:0000033, GO:0005528=GO_REF:0000033, GO:0007283=GO_REF:0000019} O75344 Peptidyl-prolyl cis-trans isomerase FKBP6 protein 20110126 {GO:0016020=IBA, GO:0000239=IEA, GO:0006457=IEA, GO:0018208=IBA, GO:0003755=IBA, GO:0005528=IBA, GO:0007283=IEA} pachytene, peptidyl-proline modification, protein folding, spermatogenesis membrane FK506 binding, peptidyl-prolyl cis-trans isomerase activity Human PANTHER:PTN000054102 FKBP7 HPA UniProtKB {GO:0000413=GO_REF:0000033, GO:0016020=GO_REF:0000033, GO:0005783=GO_REF:0000052, GO:0006457=GO_REF:0000037, GO:0018208=GO_REF:0000033, GO:0005509=GO_REF:0000019, GO:0003755=GO_REF:0000033, GO:0005528=GO_REF:0000033, GO:0005788=GO_REF:0000039} Q9Y680 Peptidyl-prolyl cis-trans isomerase FKBP7 protein 20081203 {GO:0000413=IBA, GO:0016020=IBA, GO:0005783=IDA, GO:0006457=IEA, GO:0018208=IBA, GO:0005509=IEA, GO:0003755=IBA, GO:0005528=IBA, GO:0005788=IEA} peptidyl-proline modification, protein folding, protein peptidyl-prolyl isomerization endoplasmic reticulum, endoplasmic reticulum lumen, membrane FK506 binding, calcium ion binding, peptidyl-prolyl cis-trans isomerase activity Human FKBP8 GOC UniProtKB {GO:0000413=GO_REF:0000033, GO:0005515=PMID:20029029, GO:0035556=PMID:10197430, GO:0031966=GO_REF:0000039, GO:0006457=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0018208=GO_REF:0000033, GO:0003755=GO_REF:0000033, GO:0005528=GO_REF:0000033, GO:0006915=GO_REF:0000037, GO:0030176=GO_REF:0000033, GO:0005740=GO_REF:0000033} Q14318 Peptidyl-prolyl cis-trans isomerase FKBP8 protein 20130413 {GO:0000413=IBA, GO:0005515=IPI, GO:0035556=TAS, GO:0031966=IEA, GO:0006457=IEA, GO:0019048=IEA, GO:0018208=IBA, GO:0003755=IBA, GO:0005528=IBA, GO:0006915=IEA, GO:0030176=IBA, GO:0005740=IBA} apoptotic process, intracellular signal transduction, peptidyl-proline modification, protein folding, protein peptidyl-prolyl isomerization, virus-host interaction integral to endoplasmic reticulum membrane, mitochondrial envelope, mitochondrial membrane FK506 binding, peptidyl-prolyl cis-trans isomerase activity, protein binding Human PANTHER:PTN000054102 FKBP9 GOC UniProtKB {GO:0000413=GO_REF:0000033, GO:0016020=GO_REF:0000033, GO:0005783=GO_REF:0000033, GO:0006457=GO_REF:0000024, GO:0018208=GO_REF:0000033, GO:0005509=GO_REF:0000024, GO:0003755=GO_REF:0000033, GO:0005528=GO_REF:0000033} O95302 Peptidyl-prolyl cis-trans isomerase FKBP9 protein 20130413 {GO:0000413=IBA, GO:0016020=IBA, GO:0005783=IBA, GO:0006457=ISS, GO:0018208=IBA, GO:0005509=ISS, GO:0003755=IBA, GO:0005528=IBA} peptidyl-proline modification, protein folding, protein peptidyl-prolyl isomerization endoplasmic reticulum, membrane FK506 binding, calcium ion binding, peptidyl-prolyl cis-trans isomerase activity Human PANTHER:PTN000054102 FKBP9L InterPro UniProtKB {GO:0006457=GO_REF:0000002, GO:0005509=GO_REF:0000002} Q75LS8 Putative FK506-binding protein 9-like protein protein 20130413 {GO:0006457=IEA, GO:0005509=IEA} protein folding calcium ion binding Human InterPro:IPR001179 FKBPL GOC UniProtKB {GO:0000413=GO_REF:0000033, GO:0009314=PMID:10521921, GO:0016020=GO_REF:0000033, GO:0018208=GO_REF:0000033, GO:0003755=GO_REF:0000033, GO:0005528=GO_REF:0000033, GO:0005634=GO_REF:0000033} Q9UIM3 FK506-binding protein-like protein 20130413 {GO:0000413=IBA, GO:0009314=NAS, GO:0016020=IBA, GO:0018208=IBA, GO:0003755=IBA, GO:0005528=IBA, GO:0005634=IBA} peptidyl-proline modification, protein peptidyl-prolyl isomerization, response to radiation membrane, nucleus FK506 binding, peptidyl-prolyl cis-trans isomerase activity Human PANTHER:PTN000054102 FKTN BHF-UCL UniProtKB {GO:0005801=PMID:15213246, GO:0005794=PMID:18808525, GO:0008285=PMID:18808525, GO:0005783=PMID:18808525, GO:0005634=PMID:18808525, GO:0060049=PMID:18808525, GO:0005615=PMID:9690476, GO:0007399=PMID:9690476, GO:0007517=PMID:9690476, GO:0046329=PMID:18808525, GO:0000139=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0016740=GO_REF:0000037} O75072 Fukutin protein 20110404 {GO:0005801=IDA, GO:0005794=IDA, GO:0008285=IMP, GO:0005783=IDA, GO:0005634=IDA, GO:0060049=NAS, GO:0005615=TAS, GO:0007399=TAS, GO:0007517=TAS, GO:0046329=IMP, GO:0000139=IEA, GO:0016021=IEA, GO:0016740=IEA} muscle organ development, negative regulation of JNK cascade, negative regulation of cell proliferation, nervous system development, regulation of protein glycosylation Golgi apparatus, Golgi membrane, cis-Golgi network, endoplasmic reticulum, extracellular space, integral to membrane, nucleus transferase activity Human FLAD1 Reactome UniProtKB {GO:0006771=Reactome:REACT_11070, GO:0003919=GO_REF:0000003, GO:0006766=Reactome:REACT_11193, GO:0006777=GO_REF:0000002, GO:0006767=Reactome:REACT_11238, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_11128, GO:0006747=GO_REF:0000041} Q8NFF5 FAD synthase protein 20130301 {GO:0006771=TAS, GO:0003919=IEA, GO:0006766=TAS, GO:0006777=IEA, GO:0006767=TAS, GO:0044281=TAS, GO:0003824=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0006747=IEA} FAD biosynthetic process, Mo-molybdopterin cofactor biosynthetic process, riboflavin metabolic process, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cytosol ATP binding, FMN adenylyltransferase activity, catalytic activity Human FLCN HPA UniProtKB {GO:0005515=PMID:17028174, GO:0051898=GO_REF:0000024, GO:0032006=GO_REF:0000024, GO:0032007=GO_REF:0000024, GO:0030308=PMID:20573232, GO:0032008=GO_REF:0000024, GO:0005886=GO_REF:0000052, GO:0035065=GO_REF:0000024, GO:0005634=PMID:17028174, GO:0032403=PMID:17028174, GO:0005737=GO_REF:0000052, GO:0070373=GO_REF:0000024, GO:0030511=GO_REF:0000024, GO:2001170=GO_REF:0000024, GO:0030097=GO_REF:0000024, GO:0031929=PMID:17028174, GO:1901723=GO_REF:0000024, GO:0030336=PMID:22965878, GO:0043065=GO_REF:0000024, GO:0006950=PMID:17028174, GO:0010823=GO_REF:0000024, GO:0001701=GO_REF:0000024, GO:0045785=PMID:21209915, GO:0010628=GO_REF:0000024, GO:2000973=GO_REF:0000024, GO:0010629=GO_REF:0000024, GO:0001934=GO_REF:0000024, GO:0007043=GO_REF:0000024, GO:0001932=PMID:18663353, GO:2000506=GO_REF:0000024} Q8NFG4 Folliculin protein 20101115 {GO:0005515=IPI, GO:0051898=ISS, GO:0032006=ISS, GO:0032007=ISS, GO:0030308=IDA, GO:0032008=ISS, GO:0005886=IDA, GO:0035065=ISS, GO:0005634=IDA, GO:0032403=IDA, GO:0005737=IDA, GO:0070373=ISS, GO:0030511=ISS, GO:2001170=ISS, GO:0030097=ISS, GO:0031929=IMP, GO:1901723=ISS, GO:0030336=IMP, GO:0043065=ISS, GO:0006950=IMP, GO:0010823=ISS, GO:0001701=ISS, GO:0045785=IMP, GO:0010628=ISS, GO:2000973=ISS, GO:0010629=ISS, GO:0001934=ISS, GO:0007043=ISS, GO:0001932=IDA, GO:2000506=ISS} TOR signaling cascade, cell-cell junction assembly, hemopoiesis, in utero embryonic development, negative regulation of ATP biosynthetic process, negative regulation of ERK1 and ERK2 cascade, negative regulation of TOR signaling cascade, negative regulation of cell growth, negative regulation of cell migration, negative regulation of cell proliferation involved in kidney development, negative regulation of energy homeostasis, negative regulation of gene expression, negative regulation of mitochondrion organization, negative regulation of protein kinase B signaling cascade, positive regulation of TOR signaling cascade, positive regulation of apoptotic process, positive regulation of cell adhesion, positive regulation of gene expression, positive regulation of protein phosphorylation, positive regulation of transforming growth factor beta receptor signaling pathway, regulation of TOR signaling cascade, regulation of histone acetylation, regulation of pro-B cell differentiation, regulation of protein phosphorylation, response to stress cytoplasm, nucleus, plasma membrane protein binding, protein complex binding Human FLG BHF-UCL UniProtKB {GO:0005882=PMID:2740331, GO:0030216=PMID:17704059, GO:0005198=PMID:2740331, GO:0005509=GO_REF:0000002, GO:0016023=PMID:12850301, GO:0007275=PMID:2740331, GO:0001533=GO_REF:0000019} P20930 Filaggrin protein 20081118 {GO:0005882=NAS, GO:0030216=TAS, GO:0005198=NAS, GO:0005509=IEA, GO:0016023=IDA, GO:0007275=NAS, GO:0001533=IEA} keratinocyte differentiation, multicellular organismal development cornified envelope, cytoplasmic membrane-bounded vesicle, intermediate filament calcium ion binding, structural molecule activity Human FLG2 InterPro UniProtKB {GO:0005198=GO_REF:0000002, GO:0005509=GO_REF:0000002} Q5D862 Filaggrin-2 protein 20130413 {GO:0005198=IEA, GO:0005509=IEA} calcium ion binding, structural molecule activity Human InterPro:IPR001751|InterPro:IPR002048|InterPro:IPR011992 FLI1 PINC UniProtKB {GO:0007599=PMID:10891501, GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0008015=GO_REF:0000019, GO:0009887=GO_REF:0000019, GO:0000980=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0003677=PMID:1522903, GO:0006351=GO_REF:0000037} Q01543 Friend leukemia integration 1 transcription factor protein 20030904 {GO:0007599=TAS, GO:0043565=IEA, GO:0003700=IEA, GO:0008015=IEA, GO:0009887=IEA, GO:0000980=IEA, GO:0005634=IEA, GO:0003677=TAS, GO:0006351=IEA} blood circulation, hemostasis, organ morphogenesis, transcription, DNA-dependent nucleus DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human FLII HPA UniProtKB {GO:0005515=PMID:10366446, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0006936=PMID:9177775, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0007275=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0005925=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q13045 Protein flightless-1 homolog protein 20080818 {GO:0005515=IPI, GO:0005813=IDA, GO:0005737=IDA, GO:0006355=IEA, GO:0006936=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0007275=IEA, GO:0003779=IEA, GO:0005925=IEA, GO:0006351=IEA} multicellular organismal development, muscle contraction, regulation of transcription, DNA-dependent, transcription, DNA-dependent centrosome, cytoplasm, focal adhesion, nucleolus, nucleus actin binding, protein binding Human FLNA UniProtKB UniProtKB {GO:0005802=GO_REF:0000019, GO:0005515=PMID:10692483, GO:0031267=PMID:10051605, GO:0005886=GO_REF:0000052, GO:0031523=PMID:18548008, GO:0005634=PMID:15684392, GO:0007195=PMID:10692483, GO:0001837=GO_REF:0000019, GO:0045022=GO_REF:0000019, GO:0015629=GO_REF:0000052, GO:0042993=PMID:15684392, GO:0042803=PMID:2391361, GO:0043433=PMID:15684392, GO:0045184=PMID:18322202, GO:0005829=Reactome:REACT_23834, GO:0005737=GO_REF:0000052, GO:0001948=PMID:3138234, GO:0051015=PMID:4044584, GO:0005080=GO_REF:0000019, GO:0051764=PMID:10051605, GO:0004871=PMID:12761501, GO:0090307=PMID:18548008, GO:0043123=PMID:12761501, GO:0005938=GO_REF:0000039, GO:0034988=PMID:1833070, GO:0031532=PMID:10051605, GO:0042177=PMID:18322202, GO:0034329=Reactome:REACT_20676, GO:0051220=PMID:17536008, GO:0050821=PMID:18322202, GO:0030168=Reactome:REACT_798, GO:0003779=GO_REF:0000038, GO:0005576=Reactome:REACT_21347, GO:0048365=PMID:10051605, GO:0042384=PMID:22121117, GO:0007596=Reactome:REACT_604, GO:0034394=PMID:18322202, GO:0002576=Reactome:REACT_318, GO:0043113=PMID:10692483, GO:0017048=PMID:10051605, GO:0017160=PMID:10051605, GO:0008134=PMID:15684392} Q5HY54 Filamin-A protein 20130413 {GO:0005802=IEA, GO:0005515=IPI, GO:0031267=IDA, GO:0005886=IDA, GO:0031523=IDA, GO:0005634=IDA, GO:0007195=IMP, GO:0001837=IEA, GO:0045022=IEA, GO:0015629=IDA, GO:0042993=IMP, GO:0042803=IDA, GO:0043433=IDA, GO:0045184=IDA, GO:0005829=TAS, GO:0005737=IDA, GO:0001948=IDA, GO:0051015=IDA, GO:0005080=IEA, GO:0051764=IDA, GO:0004871=IMP, GO:0090307=IDA, GO:0043123=IMP, GO:0005938=IEA, GO:0034988=IDA, GO:0031532=IDA, GO:0042177=IMP, GO:0034329=TAS, GO:0051220=IMP, GO:0050821=IMP, GO:0030168=TAS, GO:0003779=IEA, GO:0005576=TAS, GO:0048365=IDA, GO:0042384=IMP, GO:0007596=TAS, GO:0034394=IDA, GO:0002576=TAS, GO:0043113=IDA, GO:0017048=IDA, GO:0017160=IDA, GO:0008134=IPI} actin crosslink formation, actin cytoskeleton reorganization, adenylate cyclase-inhibiting dopamine receptor signaling pathway, blood coagulation, cell junction assembly, cilium assembly, cytoplasmic sequestering of protein, early endosome to late endosome transport, epithelial to mesenchymal transition, establishment of protein localization, negative regulation of protein catabolic process, negative regulation of sequence-specific DNA binding transcription factor activity, platelet activation, platelet degranulation, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of transcription factor import into nucleus, protein localization to cell surface, protein stabilization, receptor clustering, spindle assembly involved in mitosis Myb complex, actin cytoskeleton, cell cortex, cytoplasm, cytosol, extracellular region, nucleus, plasma membrane, trans-Golgi network Fc-gamma receptor I complex binding, Rac GTPase binding, Ral GTPase binding, Rho GTPase binding, actin binding, actin filament binding, glycoprotein binding, protein binding, protein homodimerization activity, protein kinase C binding, signal transducer activity, small GTPase binding, transcription factor binding Human UniProtKB-KW:KW-0009 FLNB HPA UniProtKB {GO:0005515=PMID:10644691, GO:0001725=GO_REF:0000019, GO:0030018=GO_REF:0000039, GO:0030036=PMID:8327473, GO:0005886=GO_REF:0000052, GO:0019221=Reactome:REACT_25229, GO:0003779=PMID:8327473, GO:0015629=PMID:9651345, GO:0030154=GO_REF:0000037, GO:0042802=PMID:12393796, GO:0005829=Reactome:REACT_115658, GO:0007165=PMID:8327473, GO:0005737=GO_REF:0000052, GO:0007519=GO_REF:0000019, GO:0016021=PMID:8327473, GO:0005938=GO_REF:0000039, GO:0007016=PMID:9694715, GO:0005925=GO_REF:0000019} O75369 Filamin-B protein 20101115 {GO:0005515=IPI, GO:0001725=IEA, GO:0030018=IEA, GO:0030036=TAS, GO:0005886=IDA, GO:0019221=TAS, GO:0003779=NAS, GO:0015629=TAS, GO:0030154=IEA, GO:0042802=IPI, GO:0005829=TAS, GO:0007165=TAS, GO:0005737=IDA, GO:0007519=IEA, GO:0016021=NAS, GO:0005938=IEA, GO:0007016=TAS, GO:0005925=IEA} actin cytoskeleton organization, cell differentiation, cytokine-mediated signaling pathway, cytoskeletal anchoring at plasma membrane, signal transduction, skeletal muscle tissue development Z disc, actin cytoskeleton, cell cortex, cytoplasm, cytosol, focal adhesion, integral to membrane, plasma membrane, stress fiber actin binding, identical protein binding, protein binding Human FLNC BHF-UCL UniProtKB {GO:0005515=PMID:17474147, GO:0008092=PMID:17987659, GO:0030018=GO_REF:0000039, GO:0005886=GO_REF:0000052, GO:0034329=Reactome:REACT_20676, GO:0030506=PMID:21223964, GO:0003779=GO_REF:0000037, GO:0005829=Reactome:REACT_20513, GO:0048747=GO_REF:0000019, GO:0042383=PMID:21223964, GO:0016528=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0043034=PMID:21223964, GO:0005856=GO_REF:0000039} Q14315 Filamin-C protein 20120606 {GO:0005515=IPI, GO:0008092=IPI, GO:0030018=IEA, GO:0005886=IDA, GO:0034329=TAS, GO:0030506=IPI, GO:0003779=IEA, GO:0005829=TAS, GO:0048747=IEA, GO:0042383=IDA, GO:0016528=IEA, GO:0005737=IDA, GO:0043034=TAS, GO:0005856=IEA} cell junction assembly, muscle fiber development Z disc, costamere, cytoplasm, cytoskeleton, cytosol, plasma membrane, sarcolemma, sarcoplasm actin binding, ankyrin binding, cytoskeletal protein binding, protein binding Human FLOT1 BHF-UCL UniProtKB {GO:0005515=PMID:15469992, GO:0042470=GO_REF:0000039, GO:0005815=PMID:18000879, GO:0035023=GO_REF:0000019, GO:0034451=PMID:18000879, GO:0007409=GO_REF:0000019, GO:0072659=GO_REF:0000019, GO:0016600=GO_REF:0000019, GO:0042383=GO_REF:0000019, GO:0035255=GO_REF:0000019, GO:0008180=PMID:18850735, GO:0005901=PMID:9153235, GO:0045121=PMID:15469992, GO:0016021=PMID:9153235, GO:0005768=PMID:20682791} O75955 Flotillin-1 protein 20080604 {GO:0005515=IPI, GO:0042470=IEA, GO:0005815=IDA, GO:0035023=IEA, GO:0034451=IDA, GO:0007409=IEA, GO:0072659=IEA, GO:0016600=IEA, GO:0042383=IEA, GO:0035255=IEA, GO:0008180=IDA, GO:0005901=TAS, GO:0045121=IDA, GO:0016021=TAS, GO:0005768=IDA} axonogenesis, protein localization to plasma membrane, regulation of Rho protein signal transduction caveola, centriolar satellite, endosome, flotillin complex, integral to membrane, melanosome, membrane raft, microtubule organizing center, sarcolemma, signalosome ionotropic glutamate receptor binding, protein binding Human FLOT2 PINC UniProtKB {GO:0008544=PMID:8051082, GO:0005886=PMID:1769667, GO:0009986=PMID:12493773, GO:0035255=GO_REF:0000019, GO:0030139=PMID:20682791, GO:0007155=GO_REF:0000037, GO:0002080=GO_REF:0000019, GO:0016600=GO_REF:0000019, GO:0005768=PMID:20682791} Q14254 Flotillin-2 protein 20030904 {GO:0008544=TAS, GO:0005886=NAS, GO:0009986=IDA, GO:0035255=IEA, GO:0030139=IDA, GO:0007155=IEA, GO:0002080=IEA, GO:0016600=IEA, GO:0005768=IDA} cell adhesion, epidermis development acrosomal membrane, cell surface, endocytic vesicle, endosome, flotillin complex, plasma membrane ionotropic glutamate receptor binding Human FLRT1 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0005887=PMID:10644439, GO:0005578=PMID:10644439, GO:0005057=PMID:10644439, GO:0030674=PMID:10644439, GO:0007155=GO_REF:0000037} Q9NZU1 Leucine-rich repeat transmembrane protein FLRT1 protein 20061026 {GO:0008150=ND, GO:0005887=NAS, GO:0005578=NAS, GO:0005057=NAS, GO:0030674=NAS, GO:0007155=IEA} biological_process, cell adhesion integral to plasma membrane, proteinaceous extracellular matrix protein binding, bridging, receptor signaling protein activity Human FLRT2 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0005887=PMID:10644439, GO:0005578=PMID:10644439, GO:0005057=PMID:10644439, GO:0030674=PMID:10644439, GO:0007155=GO_REF:0000037} O43155 Leucine-rich repeat transmembrane protein FLRT2 protein 20010822 {GO:0008150=ND, GO:0005887=NAS, GO:0005578=NAS, GO:0005057=NAS, GO:0030674=NAS, GO:0007155=IEA} biological_process, cell adhesion integral to plasma membrane, proteinaceous extracellular matrix protein binding, bridging, receptor signaling protein activity Human FLRT3 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0005887=PMID:10644439, GO:0005578=PMID:10644439, GO:0005057=PMID:10644439, GO:0030674=PMID:10644439, GO:0007155=GO_REF:0000037} Q9NZU0 Leucine-rich repeat transmembrane protein FLRT3 protein 20010822 {GO:0008150=ND, GO:0005887=NAS, GO:0005578=NAS, GO:0005057=NAS, GO:0030674=NAS, GO:0007155=IEA} biological_process, cell adhesion integral to plasma membrane, proteinaceous extracellular matrix protein binding, bridging, receptor signaling protein activity Human FLT1 HPA UniProtKB {GO:0005515=PMID:10543948, GO:0030949=PMID:1312256, GO:0008284=PMID:10748050, GO:0035924=PMID:8605350, GO:0005886=GO_REF:0000052, GO:0048514=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0002040=GO_REF:0000019, GO:0048598=GO_REF:0000024, GO:0005615=PMID:8248162, GO:0030154=GO_REF:0000037, GO:0042802=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0046777=PMID:9299537, GO:0043552=PMID:11312102, GO:0019838=PMID:1312256, GO:0043406=PMID:9299537, GO:0036323=PMID:15952180, GO:0005021=PMID:1312256, GO:0048010=Reactome:REACT_12529, GO:0001569=GO_REF:0000019, GO:0005794=GO_REF:0000052, GO:0030335=PMID:8605350, GO:0005730=GO_REF:0000052, GO:0036326=PMID:8605350, GO:0036327=PMID:15952180, GO:0018108=PMID:9299537, GO:0014068=PMID:14633857, GO:0005524=GO_REF:0000037, GO:0045766=PMID:14633857, GO:0010863=PMID:11312102, GO:0002548=PMID:8605350, GO:0016477=PMID:8605350, GO:0005887=PMID:11513746, GO:0036332=PMID:12796773, GO:0004713=GO_REF:0000002, GO:0004714=PMID:8248162, GO:0043410=PMID:9299537, GO:0007169=PMID:2158038, GO:0005768=GO_REF:0000039} P17948 Vascular endothelial growth factor receptor 1 protein 20101115 {GO:0005515=IPI, GO:0030949=IDA, GO:0008284=TAS, GO:0035924=IDA, GO:0005886=IDA, GO:0048514=ISS, GO:0005634=IDA, GO:0002040=IEA, GO:0048598=ISS, GO:0005615=TAS, GO:0030154=IEA, GO:0042802=IEA, GO:0005737=IDA, GO:0046777=IDA, GO:0043552=IMP, GO:0019838=IPI, GO:0043406=IDA, GO:0036323=IDA, GO:0005021=IDA, GO:0048010=TAS, GO:0001569=IEA, GO:0005794=IDA, GO:0030335=IDA, GO:0005730=IDA, GO:0036326=IDA, GO:0036327=IDA, GO:0018108=IDA, GO:0014068=IMP, GO:0005524=IEA, GO:0045766=IMP, GO:0010863=IMP, GO:0002548=IDA, GO:0016477=IMP, GO:0005887=IDA, GO:0036332=IDA, GO:0004713=IEA, GO:0004714=TAS, GO:0043410=IDA, GO:0007169=TAS, GO:0005768=IEA} blood vessel morphogenesis, cell differentiation, cell migration, cellular response to vascular endothelial growth factor stimulus, embryonic morphogenesis, monocyte chemotaxis, patterning of blood vessels, peptidyl-tyrosine phosphorylation, positive regulation of MAP kinase activity, positive regulation of MAPK cascade, positive regulation of angiogenesis, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of phosphatidylinositol 3-kinase activity, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of phospholipase C activity, positive regulation of vascular endothelial growth factor receptor signaling pathway, protein autophosphorylation, sprouting angiogenesis, transmembrane receptor protein tyrosine kinase signaling pathway, vascular endothelial growth factor receptor signaling pathway, vascular endothelial growth factor receptor-1 signaling pathway Golgi apparatus, cytoplasm, endosome, extracellular space, integral to plasma membrane, nucleolus, nucleus, plasma membrane ATP binding, VEGF-A-activated receptor activity, VEGF-B-activated receptor activity, growth factor binding, identical protein binding, placental growth factor-activated receptor activity, protein binding, protein tyrosine kinase activity, transmembrane receptor protein tyrosine kinase activity, vascular endothelial growth factor-activated receptor activity Human FLT3 UniProtKB UniProtKB {GO:0005515=PMID:20098747, GO:0045578=GO_REF:0000019, GO:0008284=PMID:19549778, GO:0008285=GO_REF:0000019, GO:0019221=GO_REF:0000024, GO:0097028=GO_REF:0000024, GO:0042803=PMID:19549778, GO:0046777=PMID:19549778, GO:0043552=PMID:12951584, GO:0043406=PMID:19549778, GO:0030183=GO_REF:0000024, GO:0005021=PMID:8394751, GO:0002328=GO_REF:0000024, GO:0035726=GO_REF:0000024, GO:0038084=PMID:8394751, GO:0001776=GO_REF:0000024, GO:0030097=PMID:7507245, GO:0004896=GO_REF:0000024, GO:0042531=PMID:19549778, GO:0009986=GO_REF:0000019, GO:0018108=PMID:19549778, GO:0014068=PMID:12951584, GO:0042981=PMID:19549778, GO:0005524=GO_REF:0000038, GO:0002572=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0005887=PMID:8394751, GO:0071345=GO_REF:0000024, GO:0005788=GO_REF:0000039, GO:0046651=GO_REF:0000024, GO:0016021=GO_REF:0000038, GO:0002318=GO_REF:0000024, GO:0004714=GO_REF:0000002, GO:0043410=PMID:19549778, GO:0007169=GO_REF:0000002, GO:0043548=GO_REF:0000019} Q5VTU6 Receptor-type tyrosine-protein kinase FLT3 protein 20130413 {GO:0005515=IPI, GO:0045578=IEA, GO:0008284=TAS, GO:0008285=IEA, GO:0019221=ISS, GO:0097028=ISS, GO:0042803=TAS, GO:0046777=TAS, GO:0043552=TAS, GO:0043406=TAS, GO:0030183=ISS, GO:0005021=TAS, GO:0002328=ISS, GO:0035726=ISS, GO:0038084=TAS, GO:0001776=ISS, GO:0030097=IDA, GO:0004896=ISS, GO:0042531=TAS, GO:0009986=IEA, GO:0018108=TAS, GO:0014068=TAS, GO:0042981=TAS, GO:0005524=IEA, GO:0002572=IEA, GO:0016020=IEA, GO:0005887=TAS, GO:0071345=ISS, GO:0005788=IEA, GO:0046651=ISS, GO:0016021=IEA, GO:0002318=ISS, GO:0004714=IEA, GO:0043410=TAS, GO:0007169=IEA, GO:0043548=IEA} B cell differentiation, cellular response to cytokine stimulus, common myeloid progenitor cell proliferation, cytokine-mediated signaling pathway, dendritic cell differentiation, hemopoiesis, leukocyte homeostasis, lymphocyte proliferation, myeloid progenitor cell differentiation, negative regulation of B cell differentiation, negative regulation of cell proliferation, peptidyl-tyrosine phosphorylation, positive regulation of MAP kinase activity, positive regulation of MAPK cascade, positive regulation of cell proliferation, positive regulation of phosphatidylinositol 3-kinase activity, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of tyrosine phosphorylation of STAT protein, pro-B cell differentiation, pro-T cell differentiation, protein autophosphorylation, regulation of apoptotic process, transmembrane receptor protein tyrosine kinase signaling pathway, vascular endothelial growth factor signaling pathway cell surface, endoplasmic reticulum lumen, integral to membrane, integral to plasma membrane, membrane ATP binding, cytokine receptor activity, phosphatidylinositol 3-kinase binding, protein binding, protein homodimerization activity, transmembrane receptor protein tyrosine kinase activity, vascular endothelial growth factor-activated receptor activity Human UniProtKB-KW:KW-0812 FLT3LG ENSEMBL UniProtKB {GO:0030971=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0005102=PMID:8180375, GO:0032825=GO_REF:0000019, GO:0005125=GO_REF:0000002, GO:0005615=GO_REF:0000037, GO:0042803=GO_REF:0000019, GO:0031233=GO_REF:0000019, GO:0007165=PMID:8180375, GO:0016020=PMID:8145851, GO:0030098=GO_REF:0000019, GO:0016021=PMID:8180375, GO:0035162=PMID:21149635} Q05C96 cDNA FLJ61175, highly similar to SL cytokine protein 20130413 {GO:0030971=IEA, GO:0008284=IEA, GO:0005886=IEA, GO:0005102=TAS, GO:0032825=IEA, GO:0005125=IEA, GO:0005615=IEA, GO:0042803=IEA, GO:0031233=IEA, GO:0007165=TAS, GO:0016020=NAS, GO:0030098=IEA, GO:0016021=NAS, GO:0035162=IDA} embryonic hemopoiesis, lymphocyte differentiation, positive regulation of cell proliferation, positive regulation of natural killer cell differentiation, signal transduction extracellular space, integral to membrane, intrinsic to external side of plasma membrane, membrane, plasma membrane cytokine activity, protein homodimerization activity, receptor binding, receptor tyrosine kinase binding Human Ensembl:ENSMUSP00000082492 FLT4 BHF-UCL UniProtKB {GO:0005515=PMID:22939624, GO:0008284=PMID:11574540, GO:0035924=PMID:19779139, GO:0005886=Reactome:REACT_12533, GO:0048514=GO_REF:0000024, GO:0046330=PMID:16076871, GO:0005634=GO_REF:0000039, GO:0002040=GO_REF:0000024, GO:0001946=PMID:19779139, GO:0005737=GO_REF:0000039, GO:0046777=PMID:7675451, GO:0090037=PMID:11532940, GO:0060312=GO_REF:0000024, GO:0019838=PMID:9435229, GO:0005021=PMID:9012504, GO:0070374=PMID:11532940, GO:0001945=GO_REF:0000024, GO:0001944=GO_REF:0000024, GO:0048010=Reactome:REACT_12529, GO:0043066=PMID:11532940, GO:0019903=PMID:20826270, GO:0018108=PMID:7898938, GO:0005576=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0010575=PMID:19779139, GO:0010595=PMID:11532940, GO:0001938=PMID:11532940, GO:0005887=GO_REF:0000002, GO:0001934=PMID:11532940, GO:0004714=PMID:7898938, GO:0043410=PMID:19779139, GO:0007169=PMID:10835628} P35916 Vascular endothelial growth factor receptor 3 protein 20120319 {GO:0005515=IPI, GO:0008284=IGI, GO:0035924=IMP, GO:0005886=TAS, GO:0048514=ISS, GO:0046330=IMP, GO:0005634=IEA, GO:0002040=ISS, GO:0001946=IMP, GO:0005737=IEA, GO:0046777=IDA, GO:0090037=IMP, GO:0060312=ISS, GO:0019838=IPI, GO:0005021=IDA, GO:0070374=IMP, GO:0001945=ISS, GO:0001944=ISS, GO:0048010=TAS, GO:0043066=IMP, GO:0019903=IPI, GO:0018108=IDA, GO:0005576=IEA, GO:0005524=IEA, GO:0010575=IMP, GO:0010595=IMP, GO:0001938=IMP, GO:0005887=IEA, GO:0001934=IMP, GO:0004714=IMP, GO:0043410=IMP, GO:0007169=TAS} blood vessel morphogenesis, cellular response to vascular endothelial growth factor stimulus, lymph vessel development, lymphangiogenesis, negative regulation of apoptotic process, peptidyl-tyrosine phosphorylation, positive regulation of ERK1 and ERK2 cascade, positive regulation of JNK cascade, positive regulation of MAPK cascade, positive regulation of cell proliferation, positive regulation of endothelial cell migration, positive regulation of endothelial cell proliferation, positive regulation of protein kinase C signaling cascade, positive regulation of protein phosphorylation, positive regulation vascular endothelial growth factor production, protein autophosphorylation, regulation of blood vessel remodeling, sprouting angiogenesis, transmembrane receptor protein tyrosine kinase signaling pathway, vascular endothelial growth factor receptor signaling pathway, vasculature development cytoplasm, extracellular region, integral to plasma membrane, nucleus, plasma membrane ATP binding, growth factor binding, protein binding, protein phosphatase binding, transmembrane receptor protein tyrosine kinase activity, vascular endothelial growth factor-activated receptor activity Human UniProtKB:P35917 FLVCR1 Reactome UniProtKB {GO:0005515=PMID:20610401, GO:0005215=PMID:10648427, GO:0008219=GO_REF:0000037, GO:0046620=GO_REF:0000019, GO:0005886=Reactome:REACT_25203, GO:0015232=PMID:20610401, GO:0007275=PMID:10648427, GO:0048536=GO_REF:0000019, GO:0097037=PMID:15369674, GO:0055085=Reactome:REACT_15518, GO:0001701=GO_REF:0000019, GO:0006879=Reactome:REACT_25060, GO:0035264=GO_REF:0000019, GO:0005887=PMID:10648427, GO:0060323=GO_REF:0000019, GO:0030218=GO_REF:0000019, GO:0006810=PMID:10648427, GO:0016021=GO_REF:0000002, GO:0042733=GO_REF:0000019} Q9Y5Y0 Feline leukemia virus subgroup C receptor-related protein 1 protein 20130301 {GO:0005515=IPI, GO:0005215=TAS, GO:0008219=IEA, GO:0046620=IEA, GO:0005886=TAS, GO:0015232=IDA, GO:0007275=TAS, GO:0048536=IEA, GO:0097037=IMP, GO:0055085=TAS, GO:0001701=IEA, GO:0006879=TAS, GO:0035264=IEA, GO:0005887=TAS, GO:0060323=IEA, GO:0030218=IEA, GO:0006810=TAS, GO:0016021=IEA, GO:0042733=IEA} cell death, cellular iron ion homeostasis, embryonic digit morphogenesis, erythrocyte differentiation, head morphogenesis, heme export, in utero embryonic development, multicellular organism growth, multicellular organismal development, regulation of organ growth, spleen development, transmembrane transport, transport integral to membrane, integral to plasma membrane, plasma membrane heme transporter activity, protein binding, transporter activity Human FLYWCH1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q4VC44 FLYWCH-type zinc finger-containing protein 1 protein 20111111 {GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0046872=IEA} cytoplasm, nucleolus, nucleus DNA binding, metal ion binding Human FLYWCH2 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q96CP2 FLYWCH family member 2 protein 20110303 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human FMN1 UniProtKB UniProtKB {GO:0035137=GO_REF:0000019, GO:0010467=GO_REF:0000019, GO:0035136=GO_REF:0000019, GO:0017124=GO_REF:0000019, GO:0030036=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0048705=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0015629=GO_REF:0000002, GO:0003677=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0005912=GO_REF:0000039, GO:0030838=GO_REF:0000019, GO:0051127=GO_REF:0000019} Q68DA7 Formin-1 protein 20130413 {GO:0035137=IEA, GO:0010467=IEA, GO:0035136=IEA, GO:0017124=IEA, GO:0030036=IEA, GO:0005886=IEA, GO:0048705=IEA, GO:0003779=IEA, GO:0005634=IEA, GO:0015629=IEA, GO:0003677=IEA, GO:0005737=IEA, GO:0005912=IEA, GO:0030838=IEA, GO:0051127=IEA} actin cytoskeleton organization, forelimb morphogenesis, gene expression, hindlimb morphogenesis, positive regulation of actin filament polymerization, positive regulation of actin nucleation, skeletal system morphogenesis actin cytoskeleton, adherens junction, cytoplasm, nucleus, plasma membrane DNA binding, SH3 domain binding, actin binding Human UniProtKB-SubCell:SL-0009 FMNL1 IntAct UniProtKB {GO:0005515=PMID:21148482, GO:0030036=GO_REF:0000002, GO:0005886=GO_REF:0000024, GO:0006929=GO_REF:0000019, GO:0008360=PMID:21834987, GO:0003779=GO_REF:0000002, GO:0005829=GO_REF:0000024, GO:0045335=GO_REF:0000024, GO:0032794=PMID:21148482, GO:0051014=GO_REF:0000024, GO:0003674=GO_REF:0000015, GO:0048365=GO_REF:0000024, GO:0032059=GO_REF:0000039, GO:0051015=GO_REF:0000024, GO:0030866=PMID:21834987, GO:0005522=GO_REF:0000019, GO:0005938=GO_REF:0000039} O95466 Formin-like protein 1 protein 20130415 {GO:0005515=IPI, GO:0030036=IEA, GO:0005886=ISS, GO:0006929=IEA, GO:0008360=IMP, GO:0003779=IEA, GO:0005829=ISS, GO:0045335=ISS, GO:0032794=IDA, GO:0051014=ISS, GO:0003674=ND, GO:0048365=ISS, GO:0032059=IEA, GO:0051015=ISS, GO:0030866=IMP, GO:0005522=IEA, GO:0005938=IEA} actin cytoskeleton organization, actin filament severing, cortical actin cytoskeleton organization, regulation of cell shape, substrate-dependent cell migration bleb, cell cortex, cytosol, phagocytic vesicle, plasma membrane GTPase activating protein binding, Rac GTPase binding, actin binding, actin filament binding, molecular_function, profilin binding, protein binding Human UniProtKB:O75044 FMNL2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0030036=GO_REF:0000002, GO:0030866=PMID:21834987, GO:0022604=PMID:21834987, GO:0007010=PMID:21834987, GO:0017048=GO_REF:0000002, GO:0003779=GO_REF:0000002} Q96PY5 Formin-like protein 2 protein 20110926 {GO:0005737=IEA, GO:0030036=IEA, GO:0030866=IMP, GO:0022604=IMP, GO:0007010=IMP, GO:0017048=IEA, GO:0003779=IEA} actin cytoskeleton organization, cortical actin cytoskeleton organization, cytoskeleton organization, regulation of cell morphogenesis cytoplasm Rho GTPase binding, actin binding Human FMNL3 UniProtKB UniProtKB {GO:0032794=GO_REF:0000024, GO:0005737=PMID:21834987, GO:0030036=GO_REF:0000002, GO:0016477=PMID:21834987, GO:0008360=PMID:21834987, GO:0007010=PMID:21834987, GO:0017048=GO_REF:0000002, GO:0003779=GO_REF:0000002} Q8IVF7 Formin-like protein 3 protein 20120606 {GO:0032794=ISS, GO:0005737=IDA, GO:0030036=IEA, GO:0016477=IMP, GO:0008360=IMP, GO:0007010=IMP, GO:0017048=IEA, GO:0003779=IEA} actin cytoskeleton organization, cell migration, cytoskeleton organization, regulation of cell shape cytoplasm GTPase activating protein binding, Rho GTPase binding, actin binding Human UniProtKB:Q6ZPF4 FMO1 ENSEMBL UniProtKB {GO:0050661=GO_REF:0000002, GO:0006805=Reactome:REACT_13705, GO:0050660=GO_REF:0000002, GO:0031227=GO_REF:0000002, GO:0006970=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0006082=PMID:15144220, GO:0043231=GO_REF:0000019, GO:0070995=PMID:15144220, GO:0004497=PMID:1712018, GO:0004499=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0005788=Reactome:REACT_13805, GO:0016021=GO_REF:0000037, GO:0009404=PMID:15144220} Q5QPT3 "Dimethylaniline monooxygenase ""N-oxide-forming"" 1" protein 20130413 {GO:0050661=IEA, GO:0006805=TAS, GO:0050660=IEA, GO:0031227=IEA, GO:0006970=IEA, GO:0044281=TAS, GO:0006082=IDA, GO:0043231=IEA, GO:0070995=IDA, GO:0004497=TAS, GO:0004499=IEA, GO:0032496=IEA, GO:0005788=TAS, GO:0016021=IEA, GO:0009404=IDA} NADPH oxidation, organic acid metabolic process, response to lipopolysaccharide, response to osmotic stress, small molecule metabolic process, toxin metabolic process, xenobiotic metabolic process endoplasmic reticulum lumen, integral to membrane, intracellular membrane-bounded organelle, intrinsic to endoplasmic reticulum membrane N,N-dimethylaniline monooxygenase activity, NADP binding, flavin adenine dinucleotide binding, monooxygenase activity Human Ensembl:ENSRNOP00000044613 FMO3 Reactome UniProtKB {GO:0050661=GO_REF:0000019, GO:0006805=Reactome:REACT_13705, GO:0034899=GO_REF:0000003, GO:0004499=Reactome:REACT_236, GO:0017144=GO_REF:0000019, GO:0050660=GO_REF:0000002, GO:0005789=Reactome:REACT_236, GO:0031227=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0016597=GO_REF:0000019, GO:0043231=PMID:9207220} P31513 "Dimethylaniline monooxygenase ""N-oxide-forming"" 3" protein 20120320 {GO:0050661=IEA, GO:0006805=TAS, GO:0034899=IEA, GO:0004499=TAS, GO:0017144=IEA, GO:0050660=IEA, GO:0005789=TAS, GO:0031227=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0016597=IEA, GO:0043231=TAS} drug metabolic process, small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle, intrinsic to endoplasmic reticulum membrane N,N-dimethylaniline monooxygenase activity, NADP binding, amino acid binding, flavin adenine dinucleotide binding, trimethylamine monooxygenase activity Human FMO4 UniProtKB UniProtKB {GO:0050661=GO_REF:0000002, GO:0006805=GO_REF:0000029, GO:0004499=PMID:1417778, GO:0050660=GO_REF:0000002, GO:0031227=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0043231=GO_REF:0000029} P31512 "Dimethylaniline monooxygenase ""N-oxide-forming"" 4" protein 20021104 {GO:0050661=IEA, GO:0006805=NAS, GO:0004499=NAS, GO:0050660=IEA, GO:0031227=IEA, GO:0016021=IEA, GO:0043231=NAS} xenobiotic metabolic process integral to membrane, intracellular membrane-bounded organelle, intrinsic to endoplasmic reticulum membrane N,N-dimethylaniline monooxygenase activity, NADP binding, flavin adenine dinucleotide binding Human FMOD Reactome UniProtKB {GO:0007181=PMID:8093006, GO:0018146=Reactome:REACT_121120, GO:0005975=Reactome:REACT_474, GO:0005796=Reactome:REACT_121317, GO:0042340=Reactome:REACT_121313, GO:0005578=GO_REF:0000039, GO:0005576=Reactome:REACT_121303, GO:0044281=Reactome:REACT_111217, GO:0030203=Reactome:REACT_121315, GO:0043202=Reactome:REACT_121303, GO:0042339=Reactome:REACT_121288} Q06828 Fibromodulin protein 20130301 {GO:0007181=TAS, GO:0018146=TAS, GO:0005975=TAS, GO:0005796=TAS, GO:0042340=TAS, GO:0005578=IEA, GO:0005576=TAS, GO:0044281=TAS, GO:0030203=TAS, GO:0043202=TAS, GO:0042339=TAS} carbohydrate metabolic process, glycosaminoglycan metabolic process, keratan sulfate biosynthetic process, keratan sulfate catabolic process, keratan sulfate metabolic process, small molecule metabolic process, transforming growth factor beta receptor complex assembly Golgi lumen, extracellular region, lysosomal lumen, proteinaceous extracellular matrix Human FMR1 InterPro UniProtKB {GO:0005515=PMID:11438699, GO:0071598=GO_REF:0000019, GO:0010494=GO_REF:0000019, GO:0003723=GO_REF:0000002, GO:0005730=PMID:16407062, GO:0045202=GO_REF:0000019, GO:0003729=PMID:7692601, GO:0007417=GO_REF:0000019, GO:0005737=PMID:16407062, GO:0043197=GO_REF:0000019, GO:0043198=GO_REF:0000019, GO:0042788=PMID:12837692, GO:0045947=GO_REF:0000024, GO:0005654=PMID:10888599, GO:0051028=GO_REF:0000037, GO:0005845=GO_REF:0000024} Q8IXW7 FMR1 protein protein 20130413 {GO:0005515=IPI, GO:0071598=IEA, GO:0010494=IEA, GO:0003723=IEA, GO:0005730=TAS, GO:0045202=IEA, GO:0003729=TAS, GO:0007417=IEA, GO:0005737=TAS, GO:0043197=IEA, GO:0043198=IEA, GO:0042788=TAS, GO:0045947=ISS, GO:0005654=TAS, GO:0051028=IEA, GO:0005845=ISS} central nervous system development, mRNA transport, negative regulation of translational initiation cytoplasm, cytoplasmic stress granule, dendritic shaft, dendritic spine, mRNA cap binding complex, neuronal ribonucleoprotein granule, nucleolus, nucleoplasm, polysomal ribosome, synapse RNA binding, mRNA binding, protein binding Human InterPro:IPR004087|InterPro:IPR004088 FN1 BHF-UCL UniProtKB {GO:0005515=PMID:2531657, GO:0008360=GO_REF:0000037, GO:0005518=PMID:3024962, GO:0050900=Reactome:REACT_12051, GO:0016324=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0034446=PMID:16236823, GO:0031093=Reactome:REACT_21351, GO:0007155=PMID:1423622, GO:0008201=PMID:10075919, GO:0005793=PMID:15308636, GO:0005578=GO_REF:0000029, GO:0009611=PMID:7989369, GO:0030168=Reactome:REACT_798, GO:0005577=PMID:3997886, GO:0005576=Reactome:REACT_160174, GO:0006953=GO_REF:0000037, GO:0001525=GO_REF:0000037, GO:0005604=GO_REF:0000019, GO:0031012=PMID:22261194, GO:0016504=GO_REF:0000019, GO:0018149=PMID:3997886, GO:0016477=GO_REF:0000029, GO:0007161=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0007044=GO_REF:0000019, GO:0005201=GO_REF:0000029} P02751 Fibronectin protein 20110114 {GO:0005515=IPI, GO:0008360=IEA, GO:0005518=NAS, GO:0050900=TAS, GO:0016324=IEA, GO:0030198=TAS, GO:0034446=IDA, GO:0031093=TAS, GO:0007155=NAS, GO:0008201=NAS, GO:0005793=IDA, GO:0005578=NAS, GO:0009611=NAS, GO:0030168=TAS, GO:0005577=IDA, GO:0005576=TAS, GO:0006953=IEA, GO:0001525=IEA, GO:0005604=IEA, GO:0031012=ISS, GO:0016504=IEA, GO:0018149=IDA, GO:0016477=NAS, GO:0007161=IEA, GO:0007596=TAS, GO:0002576=TAS, GO:0007044=IEA, GO:0005201=NAS} acute-phase response, angiogenesis, blood coagulation, calcium-independent cell-matrix adhesion, cell adhesion, cell migration, cell-substrate junction assembly, extracellular matrix organization, leukocyte migration, peptide cross-linking, platelet activation, platelet degranulation, regulation of cell shape, response to wounding, substrate adhesion-dependent cell spreading apical plasma membrane, basement membrane, endoplasmic reticulum-Golgi intermediate compartment, extracellular matrix, extracellular region, fibrinogen complex, platelet alpha granule lumen, proteinaceous extracellular matrix collagen binding, extracellular matrix structural constituent, heparin binding, peptidase activator activity, protein binding Human UniProtKB:P08519 FN3KRP UniProtKB UniProtKB {GO:0016301=GO_REF:0000037, GO:0016772=GO_REF:0000002} Q9HA64 Ketosamine-3-kinase protein 20130413 {GO:0016301=IEA, GO:0016772=IEA} kinase activity, transferase activity, transferring phosphorus-containing groups Human UniProtKB-KW:KW-0418 FNBP1 IntAct UniProtKB {GO:0005515=PMID:20562859, GO:0005905=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0016023=GO_REF:0000039, GO:0005856=GO_REF:0000039, GO:0005938=GO_REF:0000039, GO:0005764=GO_REF:0000039, GO:0042802=PMID:17512409, GO:0008289=GO_REF:0000037, GO:0006897=GO_REF:0000037} Q96RU3 Formin-binding protein 1 protein 20130415 {GO:0005515=IPI, GO:0005905=IEA, GO:0005886=IEA, GO:0016023=IEA, GO:0005856=IEA, GO:0005938=IEA, GO:0005764=IEA, GO:0042802=IPI, GO:0008289=IEA, GO:0006897=IEA} endocytosis cell cortex, coated pit, cytoplasmic membrane-bounded vesicle, cytoskeleton, lysosome, plasma membrane identical protein binding, lipid binding, protein binding Human UniProtKB:Q96RU3 FNBP1L BHF-UCL UniProtKB {GO:0005515=PMID:20730103, GO:0072583=PMID:20730103, GO:0005886=GO_REF:0000039, GO:0097320=PMID:20730103, GO:0006914=GO_REF:0000037, GO:0051491=PMID:20730103, GO:0006900=PMID:20730103, GO:0008289=GO_REF:0000037, GO:0016050=PMID:20730103, GO:0030050=PMID:20730103, GO:0016023=PMID:20730103, GO:0005856=GO_REF:0000039, GO:0005938=GO_REF:0000039, GO:0010324=PMID:20730103} Q5T0N5 Formin-binding protein 1-like protein 20120517 {GO:0005515=IPI, GO:0072583=IDA, GO:0005886=IEA, GO:0097320=IDA, GO:0006914=IEA, GO:0051491=IDA, GO:0006900=IDA, GO:0008289=IEA, GO:0016050=IDA, GO:0030050=IDA, GO:0016023=IDA, GO:0005856=IEA, GO:0005938=IEA, GO:0010324=IDA} autophagy, clathrin-mediated endocytosis, membrane budding, membrane invagination, membrane tubulation, positive regulation of filopodium assembly, vesicle organization, vesicle transport along actin filament cell cortex, cytoplasmic membrane-bounded vesicle, cytoskeleton, plasma membrane lipid binding, protein binding Human FNBP4 HPA UniProtKB {GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q8N3X1 Formin-binding protein 4 protein 20111111 {GO:0005730=IDA, GO:0005634=IDA} nucleolus, nucleus NOT Human FNDC3A UniProtKB UniProtKB {GO:0012506=GO_REF:0000019, GO:0009566=GO_REF:0000019, GO:0016337=GO_REF:0000019, GO:0005794=PMID:18218838, GO:0060009=GO_REF:0000019, GO:0000139=GO_REF:0000039, GO:0001669=GO_REF:0000019, GO:0007286=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0005829=GO_REF:0000019} Q9Y2H6 Fibronectin type-III domain-containing protein 3A protein 20090622 {GO:0012506=IEA, GO:0009566=IEA, GO:0016337=IEA, GO:0005794=IDA, GO:0060009=IEA, GO:0000139=IEA, GO:0001669=IEA, GO:0007286=IEA, GO:0016021=IEA, GO:0005829=IEA} Sertoli cell development, cell-cell adhesion, fertilization, spermatid development Golgi apparatus, Golgi membrane, acrosomal vesicle, cytosol, integral to membrane, vesicle membrane Human FNDC3B HPA UniProtKB {GO:0005783=GO_REF:0000052, GO:0045600=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q53EP0 Fibronectin type III domain-containing protein 3B protein 20080205 {GO:0005783=IDA, GO:0045600=IEA, GO:0016021=IEA} positive regulation of fat cell differentiation endoplasmic reticulum, integral to membrane Human FNDC4 UniProtKB UniProtKB {GO:0005886=GO_REF:0000024, GO:0005783=GO_REF:0000024, GO:0016021=GO_REF:0000037} Q9H6D8 Fibronectin type III domain-containing protein 4 protein 20120423 {GO:0005886=ISS, GO:0005783=ISS, GO:0016021=IEA} endoplasmic reticulum, integral to membrane, plasma membrane Human UniProtKB:Q3TR08 FNDC5 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005886=GO_REF:0000024, GO:0005179=GO_REF:0000037, GO:0005783=GO_REF:0000024, GO:0014850=GO_REF:0000024, GO:0005576=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0090336=GO_REF:0000024, GO:0005778=GO_REF:0000039} Q8NAU1 Fibronectin type III domain-containing protein 5 protein 20120517 {GO:0003674=ND, GO:0008150=ND, GO:0005886=ISS, GO:0005179=IEA, GO:0005783=ISS, GO:0014850=ISS, GO:0005576=ISS, GO:0016021=IEA, GO:0090336=ISS, GO:0005778=IEA} biological_process, positive regulation of brown fat cell differentiation, response to muscle activity endoplasmic reticulum, extracellular region, integral to membrane, peroxisomal membrane, plasma membrane hormone activity, molecular_function Human FNDC7 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q5VTL7 Fibronectin type III domain-containing protein 7 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 FNIP1 IntAct UniProtKB {GO:0031929=PMID:17028174, GO:0005515=PMID:22190034, GO:0051056=GO_REF:0000002, GO:0032007=GO_REF:0000024, GO:0007264=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0005085=GO_REF:0000038, GO:2000973=GO_REF:0000024, GO:0005737=PMID:17028174, GO:0002904=GO_REF:0000024, GO:0001932=PMID:18663353, GO:0002327=GO_REF:0000024, GO:0043154=GO_REF:0000024, GO:0009267=GO_REF:0000024} Q8TF40 Folliculin-interacting protein 1 protein 20130415 {GO:0031929=IMP, GO:0005515=IPI, GO:0051056=IEA, GO:0032007=ISS, GO:0007264=IEA, GO:0005622=IEA, GO:0005085=IEA, GO:2000973=ISS, GO:0005737=IDA, GO:0002904=ISS, GO:0001932=IDA, GO:0002327=ISS, GO:0043154=ISS, GO:0009267=ISS} TOR signaling cascade, cellular response to starvation, immature B cell differentiation, negative regulation of TOR signaling cascade, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of B cell apoptotic process, regulation of pro-B cell differentiation, regulation of protein phosphorylation, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytoplasm, intracellular guanyl-nucleotide exchange factor activity, protein binding Human UniProtKB:Q9Q2G4 FNTA BHF-UCL UniProtKB {GO:0018343=PMID:19228685, GO:0008017=PMID:19228685, GO:0005515=PMID:15451670, GO:0018342=GO_REF:0000002, GO:0030971=GO_REF:0000019, GO:0018344=PMID:8106351, GO:0043014=PMID:19228685, GO:0005875=PMID:19228685, GO:0006915=Reactome:REACT_578, GO:0045213=GO_REF:0000019, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_12014, GO:0004660=PMID:19228685, GO:0004661=PMID:8106351, GO:0005737=PMID:8599089, GO:0090045=PMID:19228685, GO:0030548=GO_REF:0000019, GO:0004662=GO_REF:0000003, GO:0004663=GO_REF:0000019, GO:0090044=PMID:19228685, GO:0007179=PMID:8599089, GO:0008318=GO_REF:0000002} P49354 Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha protein 20090724 {GO:0018343=IDA, GO:0008017=IDA, GO:0005515=IPI, GO:0018342=IEA, GO:0030971=IEA, GO:0018344=TAS, GO:0043014=IDA, GO:0005875=IDA, GO:0006915=TAS, GO:0045213=IEA, GO:0006921=TAS, GO:0005829=TAS, GO:0004660=IDA, GO:0004661=TAS, GO:0005737=TAS, GO:0090045=IDA, GO:0030548=IEA, GO:0004662=IEA, GO:0004663=IEA, GO:0090044=IDA, GO:0007179=TAS, GO:0008318=IEA} apoptotic process, cellular component disassembly involved in execution phase of apoptosis, neurotransmitter receptor metabolic process, positive regulation of deacetylase activity, positive regulation of tubulin deacetylation, protein farnesylation, protein geranylgeranylation, protein prenylation, transforming growth factor beta receptor signaling pathway cytoplasm, cytosol, microtubule associated complex CAAX-protein geranylgeranyltransferase activity, Rab geranylgeranyltransferase activity, acetylcholine receptor regulator activity, alpha-tubulin binding, microtubule binding, protein binding, protein farnesyltransferase activity, protein geranylgeranyltransferase activity, protein prenyltransferase activity, receptor tyrosine kinase binding contributes_to Human FNTB BHF-UCL UniProtKB {GO:0004660=PMID:19228685, GO:0005515=PMID:15451670, GO:0018343=PMID:19228685, GO:0005875=PMID:19228685, GO:0042127=GO_REF:0000002, GO:0005965=GO_REF:0000002, GO:0046872=GO_REF:0000037} P49356 Protein farnesyltransferase subunit beta protein 20090724 {GO:0004660=IDA, GO:0005515=IPI, GO:0018343=IDA, GO:0005875=IDA, GO:0042127=IEA, GO:0005965=IEA, GO:0046872=IEA} protein farnesylation, regulation of cell proliferation microtubule associated complex, protein farnesyltransferase complex metal ion binding, protein binding, protein farnesyltransferase activity Human FOLH1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0006760=GO_REF:0000019, GO:0016020=PMID:9375657, GO:0005887=GO_REF:0000019, GO:0006508=PMID:9375657, GO:0004180=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0008233=PMID:9375657, GO:0016805=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0008237=GO_REF:0000037} Q04609 Glutamate carboxypeptidase 2 protein 20080205 {GO:0005737=IDA, GO:0006760=IEA, GO:0016020=NAS, GO:0005887=IEA, GO:0006508=NAS, GO:0004180=IEA, GO:0005634=IDA, GO:0008233=NAS, GO:0016805=IEA, GO:0046872=IEA, GO:0008237=IEA} folic acid-containing compound metabolic process, proteolysis cytoplasm, integral to plasma membrane, membrane, nucleus carboxypeptidase activity, dipeptidase activity, metal ion binding, metallopeptidase activity, peptidase activity Human FOLR1 PINC UniProtKB {GO:0008219=GO_REF:0000037, GO:0005542=PMID:1840502, GO:0016020=PMID:2768245, GO:0005886=PMID:1840502, GO:0005887=PMID:10633085, GO:0015884=PMID:9545095, GO:0004872=PMID:10633085, GO:0005576=GO_REF:0000039, GO:0046655=GO_REF:0000019, GO:0031225=GO_REF:0000037, GO:0006898=PMID:9545095} P15328 Folate receptor alpha protein 20030904 {GO:0008219=IEA, GO:0005542=NAS, GO:0016020=TAS, GO:0005886=NAS, GO:0005887=TAS, GO:0015884=TAS, GO:0004872=TAS, GO:0005576=IEA, GO:0046655=IEA, GO:0031225=IEA, GO:0006898=TAS} cell death, folic acid metabolic process, folic acid transport, receptor-mediated endocytosis anchored to membrane, extracellular region, integral to plasma membrane, membrane, plasma membrane folic acid binding, receptor activity Human FOLR2 PINC UniProtKB {GO:0005542=GO_REF:0000037, GO:0016020=PMID:2605182, GO:0005886=GO_REF:0000039, GO:0015884=PMID:2605182, GO:0005576=GO_REF:0000039, GO:0031225=GO_REF:0000037} P14207 Folate receptor beta protein 20030904 {GO:0005542=IEA, GO:0016020=TAS, GO:0005886=IEA, GO:0015884=TAS, GO:0005576=IEA, GO:0031225=IEA} folic acid transport anchored to membrane, extracellular region, membrane, plasma membrane folic acid binding Human FOLR3 PINC UniProtKB {GO:0005542=GO_REF:0000037, GO:0016020=PMID:8110752, GO:0015884=PMID:8110752, GO:0005576=GO_REF:0000039, GO:0019898=PMID:8110752} P41439 Folate receptor gamma protein 20030904 {GO:0005542=IEA, GO:0016020=TAS, GO:0015884=TAS, GO:0005576=IEA, GO:0019898=TAS} folic acid transport extracellular region, extrinsic to membrane, membrane folic acid binding Human FOPNL HPA UniProtKB {GO:0042384=PMID:15616553, GO:0005813=GO_REF:0000052, GO:0034453=GO_REF:0000002, GO:0005815=GO_REF:0000002, GO:0031514=GO_REF:0000024, GO:0034451=PMID:15616553, GO:0005634=GO_REF:0000052, GO:0005932=GO_REF:0000024} Q96NB1 LisH domain-containing protein FOPNL protein 20111111 {GO:0042384=IMP, GO:0005813=IDA, GO:0034453=IEA, GO:0005815=IEA, GO:0031514=ISS, GO:0034451=IDA, GO:0005634=IDA, GO:0005932=ISS} cilium assembly, microtubule anchoring centriolar satellite, centrosome, microtubule basal body, microtubule organizing center, motile cilium, nucleus Human FOS HPA UniProtKB {GO:0005515=PMID:20936779, GO:0003700=PMID:9732876, GO:0044212=PMID:9732876, GO:0006366=GO_REF:0000019, GO:0009409=GO_REF:0000019, GO:0051591=GO_REF:0000019, GO:0051403=Reactome:REACT_21308, GO:0002756=Reactome:REACT_6809, GO:0003690=GO_REF:0000019, GO:0031668=GO_REF:0000019, GO:0002755=Reactome:REACT_27215, GO:0032496=GO_REF:0000019, GO:0007179=PMID:9732876, GO:0009416=GO_REF:0000019, GO:0001661=GO_REF:0000019, GO:0051412=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0007568=GO_REF:0000019, GO:0009636=GO_REF:0000019, GO:0030431=GO_REF:0000019, GO:0002224=Reactome:REACT_9020, GO:0009629=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0032570=GO_REF:0000019, GO:0005654=Reactome:REACT_21404, GO:0034166=Reactome:REACT_9027, GO:0035666=Reactome:REACT_25281, GO:0045893=PMID:9732876, GO:0034162=Reactome:REACT_9047, GO:0008134=GO_REF:0000019, GO:0043005=GO_REF:0000019, GO:0034142=Reactome:REACT_6894, GO:0005634=GO_REF:0000052, GO:0060395=PMID:9732876, GO:0032870=GO_REF:0000019, GO:0051090=Reactome:REACT_21326, GO:0006954=PMID:9443941, GO:0045944=GO_REF:0000019, GO:0071277=GO_REF:0000019, GO:0034097=GO_REF:0000019, GO:0034138=Reactome:REACT_6783, GO:0005667=GO_REF:0000019, GO:0006357=PMID:10918580, GO:0042493=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0070412=PMID:9732876, GO:0003677=GO_REF:0000002, GO:0007399=GO_REF:0000019, GO:0009612=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0006306=PMID:9888853, GO:0016020=GO_REF:0000019, GO:0034614=PMID:17217916, GO:0034146=Reactome:REACT_9061} P01100 Proto-oncogene c-Fos protein 20081203 {GO:0005515=IPI, GO:0003700=IDA, GO:0044212=IDA, GO:0006366=IEA, GO:0009409=IEA, GO:0051591=IEA, GO:0051403=TAS, GO:0002756=TAS, GO:0003690=IEA, GO:0031668=IEA, GO:0002755=TAS, GO:0032496=IEA, GO:0007179=IDA, GO:0009416=IEA, GO:0001661=IEA, GO:0051412=IEA, GO:0007565=IEA, GO:0038124=TAS, GO:0038123=TAS, GO:0034134=TAS, GO:0007568=IEA, GO:0009636=IEA, GO:0030431=IEA, GO:0002224=TAS, GO:0009629=IEA, GO:0045087=TAS, GO:0032570=IEA, GO:0005654=TAS, GO:0034166=TAS, GO:0035666=TAS, GO:0045893=IDA, GO:0034162=TAS, GO:0008134=IEA, GO:0043005=IEA, GO:0034142=TAS, GO:0005634=IDA, GO:0060395=IDA, GO:0032870=IEA, GO:0051090=TAS, GO:0006954=TAS, GO:0045944=IEA, GO:0071277=IEA, GO:0034097=IEA, GO:0034138=TAS, GO:0005667=IEA, GO:0006357=TAS, GO:0042493=IEA, GO:0005730=IDA, GO:0070412=IPI, GO:0003677=IEA, GO:0007399=IEA, GO:0009612=IEA, GO:0043565=IEA, GO:0006306=TAS, GO:0016020=IEA, GO:0034614=IDA, GO:0034146=TAS} DNA methylation, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, SMAD protein signal transduction, TRIF-dependent toll-like receptor signaling pathway, aging, cellular response to calcium ion, cellular response to extracellular stimulus, cellular response to hormone stimulus, cellular response to reactive oxygen species, conditioned taste aversion, female pregnancy, inflammatory response, innate immune response, nervous system development, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of sequence-specific DNA binding transcription factor activity, regulation of transcription from RNA polymerase II promoter, response to cAMP, response to cold, response to corticosterone stimulus, response to cytokine stimulus, response to drug, response to gravity, response to light stimulus, response to lipopolysaccharide, response to mechanical stimulus, response to progesterone stimulus, response to toxic substance, sleep, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, transcription from RNA polymerase II promoter, transforming growth factor beta receptor signaling pathway membrane, neuron projection, nucleolus, nucleoplasm, nucleus, transcription factor complex DNA binding, R-SMAD binding, double-stranded DNA binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding NOT Human FOSB ENSEMBL UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0071277=GO_REF:0000019, GO:0007610=PMID:8706134, GO:0007275=PMID:8706134, GO:0005634=GO_REF:0000002, GO:0000122=PMID:1900040, GO:0003677=PMID:1900040, GO:0008134=PMID:1900040} Q49AD7 FOSB protein protein 20130413 {GO:0043565=IEA, GO:0003700=IEA, GO:0071277=IEA, GO:0007610=TAS, GO:0007275=TAS, GO:0005634=IEA, GO:0000122=TAS, GO:0003677=TAS, GO:0008134=TAS} behavior, cellular response to calcium ion, multicellular organismal development, negative regulation of transcription from RNA polymerase II promoter nucleus DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human Ensembl:ENSMUSP00000003640 FOSL1 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0042542=GO_REF:0000019, GO:0043005=GO_REF:0000019, GO:0008284=PMID:8230424, GO:0008285=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0060674=GO_REF:0000019, GO:0006366=PMID:2107490, GO:0005634=GO_REF:0000039, GO:0051591=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0051091=GO_REF:0000019, GO:0006935=PMID:10918580, GO:0031668=GO_REF:0000019, GO:0007612=GO_REF:0000019, GO:0034097=GO_REF:0000019, GO:0051412=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:0000977=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0006357=PMID:10918580, GO:0042493=GO_REF:0000019, GO:0009615=PMID:8230424, GO:0003677=GO_REF:0000002, GO:0045787=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0009612=GO_REF:0000019, GO:0007296=GO_REF:0000019, GO:0042734=GO_REF:0000019, GO:0006968=PMID:10918580, GO:0009629=GO_REF:0000019, GO:0032570=GO_REF:0000019} P15407 Fos-related antigen 1 protein 20130415 {GO:0005515=IPI, GO:0042542=IEA, GO:0043005=IEA, GO:0008284=TAS, GO:0008285=IEA, GO:0003700=IEA, GO:0060674=IEA, GO:0006366=TAS, GO:0005634=IEA, GO:0051591=IEA, GO:0005829=IEA, GO:0051091=IEA, GO:0006935=TAS, GO:0031668=IEA, GO:0007612=IEA, GO:0034097=IEA, GO:0051412=IEA, GO:0007565=IEA, GO:0000977=IEA, GO:0043065=IEA, GO:0006357=TAS, GO:0042493=IEA, GO:0009615=TAS, GO:0003677=IEA, GO:0045787=IEA, GO:0001701=IEA, GO:0009612=IEA, GO:0007296=IEA, GO:0042734=IEA, GO:0006968=TAS, GO:0009629=IEA, GO:0032570=IEA} cellular defense response, cellular response to extracellular stimulus, chemotaxis, female pregnancy, in utero embryonic development, learning, negative regulation of cell proliferation, placenta blood vessel development, positive regulation of apoptotic process, positive regulation of cell cycle, positive regulation of cell proliferation, positive regulation of sequence-specific DNA binding transcription factor activity, regulation of transcription from RNA polymerase II promoter, response to cAMP, response to corticosterone stimulus, response to cytokine stimulus, response to drug, response to gravity, response to hydrogen peroxide, response to mechanical stimulus, response to progesterone stimulus, response to virus, transcription from RNA polymerase II promoter, vitellogenesis cytosol, neuron projection, nucleus, presynaptic membrane DNA binding, RNA polymerase II regulatory region sequence-specific DNA binding, protein binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:O95751 FOSL2 HPA UniProtKB {GO:0008219=PMID:8954781, GO:0000977=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0006357=PMID:8954781, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0048146=GO_REF:0000019, GO:0006351=GO_REF:0000037} P15408 Fos-related antigen 2 protein 20090616 {GO:0008219=TAS, GO:0000977=IEA, GO:0003700=IEA, GO:0006357=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0048146=IEA, GO:0006351=IEA} cell death, positive regulation of fibroblast proliferation, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleolus, nucleus RNA polymerase II regulatory region sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity NOT Human FOXA1 BHF-UCL UniProtKB {GO:0007389=GO_REF:0000033, GO:0003700=PMID:8652662, GO:0044212=PMID:16087863, GO:0003705=GO_REF:0000033, GO:2000049=PMID:20160041, GO:0005634=PMID:20160041, GO:0010719=PMID:20160041, GO:0009790=GO_REF:0000033, GO:0010817=GO_REF:0000033, GO:0051091=PMID:16087863, GO:0003690=GO_REF:0000033, GO:0045944=PMID:20160041, GO:0006338=GO_REF:0000024, GO:0060738=GO_REF:0000033, GO:0032355=PMID:16087863, GO:0060528=GO_REF:0000033, GO:0005667=GO_REF:0000033, GO:0060743=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0019904=GO_REF:0000033, GO:0060741=GO_REF:0000033, GO:0060740=GO_REF:0000033, GO:0048665=GO_REF:0000033, GO:0042593=GO_REF:0000033, GO:0003677=PMID:9931457, GO:0043565=GO_REF:0000019, GO:0001077=GO_REF:0000024, GO:0045931=PMID:16087863, GO:0060441=GO_REF:0000033, GO:0045666=GO_REF:0000033, GO:0060487=GO_REF:0000033, GO:0033148=PMID:16087863, GO:0042445=GO_REF:0000019, GO:0008134=GO_REF:0000033} P55317 Hepatocyte nuclear factor 3-alpha protein 20110311 {GO:0007389=IBA, GO:0003700=TAS, GO:0044212=IDA, GO:0003705=IBA, GO:2000049=IC, GO:0005634=IDA, GO:0010719=IMP, GO:0009790=IBA, GO:0010817=IBA, GO:0051091=IMP, GO:0003690=IBA, GO:0045944=IDA, GO:0006338=ISS, GO:0060738=IBA, GO:0032355=IDA, GO:0060528=IBA, GO:0005667=IBA, GO:0060743=IBA, GO:0008301=IBA, GO:0019904=IBA, GO:0060741=IBA, GO:0060740=IBA, GO:0048665=IBA, GO:0042593=IBA, GO:0003677=IDA, GO:0043565=IEA, GO:0001077=ISS, GO:0045931=IMP, GO:0060441=IBA, GO:0045666=IBA, GO:0060487=IBA, GO:0033148=IMP, GO:0042445=IEA, GO:0008134=IBA} chromatin remodeling, embryo development, epithelial cell maturation involved in prostate gland development, epithelial tube branching involved in lung morphogenesis, epithelial-mesenchymal signaling involved in prostate gland development, glucose homeostasis, hormone metabolic process, lung epithelial cell differentiation, negative regulation of epithelial to mesenchymal transition, neuron fate specification, pattern specification process, positive regulation of cell-cell adhesion mediated by cadherin, positive regulation of intracellular estrogen receptor signaling pathway, positive regulation of mitotic cell cycle, positive regulation of neuron differentiation, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, prostate gland epithelium morphogenesis, prostate gland stromal morphogenesis, regulation of hormone levels, response to estradiol stimulus, secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development nucleus, transcription factor complex DNA binding, DNA binding, bending, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, protein domain specific binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding Human UniProtKB:P23512 FOXA2 BHF-UCL UniProtKB {GO:0003700=PMID:12124776, GO:0044212=PMID:15737987, GO:0003705=GO_REF:0000033, GO:2000049=PMID:20160041, GO:0003690=GO_REF:0000033, GO:0000433=GO_REF:0000024, GO:0000432=GO_REF:0000024, GO:0001705=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0023019=GO_REF:0000019, GO:0019904=GO_REF:0000033, GO:0000978=PMID:12642491, GO:0001701=GO_REF:0000033, GO:0060441=GO_REF:0000033, GO:0060487=GO_REF:0000033, GO:0070741=PMID:15737987, GO:0045893=GO_REF:0000024, GO:0008134=GO_REF:0000033, GO:0021533=GO_REF:0000033, GO:0008344=GO_REF:0000019, GO:0005634=PMID:20160041, GO:0010719=PMID:20160041, GO:0009952=GO_REF:0000033, GO:0043433=PMID:12642491, GO:0051090=GO_REF:0000033, GO:0005737=GO_REF:0000039, GO:0032525=GO_REF:0000019, GO:0045944=PMID:20160041, GO:0045945=GO_REF:0000019, GO:0040019=GO_REF:0000024, GO:0021904=GO_REF:0000033, GO:0021779=GO_REF:0000033, GO:0005667=GO_REF:0000033, GO:0006357=PMID:12911579, GO:0090009=GO_REF:0000024, GO:2000543=GO_REF:0000024, GO:0048665=GO_REF:0000033, GO:0033132=GO_REF:0000024, GO:0032289=GO_REF:0000033, GO:0003677=PMID:9931457, GO:0030193=PMID:12911579, GO:0045665=GO_REF:0000033, GO:0007492=GO_REF:0000033, GO:0045666=GO_REF:0000033, GO:0031018=PMID:12124776, GO:0071542=GO_REF:0000019, GO:2000971=GO_REF:0000024, GO:2000976=GO_REF:0000024, GO:0061178=GO_REF:0000024, GO:0016568=GO_REF:0000037} Q9Y261 Hepatocyte nuclear factor 3-beta protein 20110808 {GO:0003700=IDA, GO:0044212=IMP, GO:0003705=IBA, GO:2000049=IC, GO:0003690=IBA, GO:0000433=ISS, GO:0000432=ISS, GO:0001705=IBA, GO:0008301=IBA, GO:0023019=IEA, GO:0019904=IBA, GO:0000978=IDA, GO:0001701=IBA, GO:0060441=IBA, GO:0060487=IBA, GO:0070741=TAS, GO:0045893=ISS, GO:0008134=IBA, GO:0021533=IBA, GO:0008344=IEA, GO:0005634=IDA, GO:0010719=IMP, GO:0009952=IBA, GO:0043433=IMP, GO:0051090=IBA, GO:0005737=IEA, GO:0032525=IEA, GO:0045944=IDA, GO:0045945=IEA, GO:0040019=ISS, GO:0021904=IBA, GO:0021779=IBA, GO:0005667=IBA, GO:0006357=IDA, GO:0090009=ISS, GO:2000543=ISS, GO:0048665=IBA, GO:0033132=ISS, GO:0032289=IBA, GO:0003677=IDA, GO:0030193=IDA, GO:0045665=IBA, GO:0007492=IBA, GO:0045666=IBA, GO:0031018=IDA, GO:0071542=IEA, GO:2000971=ISS, GO:2000976=ISS, GO:0061178=ISS, GO:0016568=IEA} adult locomotory behavior, anterior/posterior pattern specification, cell differentiation in hindbrain, central nervous system myelin formation, chromatin modification, dopaminergic neuron differentiation, dorsal/ventral neural tube patterning, ectoderm formation, endocrine pancreas development, endoderm development, epithelial tube branching involved in lung morphogenesis, in utero embryonic development, lung epithelial cell differentiation, negative regulation of detection of glucose, negative regulation of epithelial to mesenchymal transition, negative regulation of glucokinase activity, negative regulation of neuron differentiation, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription from RNA polymerase II promoter by glucose, neuron fate specification, oligodendrocyte cell fate commitment, positive regulation of cell-cell adhesion mediated by cadherin, positive regulation of embryonic development, positive regulation of gastrulation, positive regulation of neuron differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter by glucose, positive regulation of transcription from RNA polymerase III promoter, positive regulation of transcription, DNA-dependent, primitive streak formation, regulation of blood coagulation, regulation of insulin secretion involved in cellular response to glucose stimulus, regulation of sequence-specific DNA binding transcription factor activity, regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter involved in detection of glucose, response to interleukin-6, signal transduction involved in regulation of gene expression, somite rostral/caudal axis specification cytoplasm, nucleus, transcription factor complex DNA binding, DNA binding, bending, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, protein domain specific binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding Human UniProtKB:P35583 FOXA3 Reactome UniProtKB {GO:0008285=GO_REF:0000033, GO:0003700=PMID:9369482, GO:0001678=PMID:9369482, GO:0044212=PMID:9369482, GO:0003705=GO_REF:0000033, GO:0005634=PMID:7739897, GO:0007283=GO_REF:0000019, GO:0009790=GO_REF:0000033, GO:0051090=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0045944=PMID:12695546, GO:0009267=GO_REF:0000033, GO:0005667=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0019904=GO_REF:0000033, GO:0048665=GO_REF:0000033, GO:0021999=GO_REF:0000033, GO:0043565=GO_REF:0000019, GO:0070368=GO_REF:0000033, GO:0060441=GO_REF:0000033, GO:0007420=GO_REF:0000033, GO:0031018=Reactome:REACT_13819, GO:0060487=GO_REF:0000033, GO:0016568=GO_REF:0000037, GO:0008134=GO_REF:0000033} P55318 Hepatocyte nuclear factor 3-gamma protein 20130301 {GO:0008285=IBA, GO:0003700=TAS, GO:0001678=TAS, GO:0044212=IMP, GO:0003705=IBA, GO:0005634=TAS, GO:0007283=IEA, GO:0009790=IBA, GO:0051090=IBA, GO:0003690=IBA, GO:0045944=IDA, GO:0009267=IBA, GO:0005667=IBA, GO:0008301=IBA, GO:0019904=IBA, GO:0048665=IBA, GO:0021999=IBA, GO:0043565=IEA, GO:0070368=IBA, GO:0060441=IRD, GO:0007420=IBA, GO:0031018=TAS, GO:0060487=IRD, GO:0016568=IEA, GO:0008134=IBA} brain development, cellular glucose homeostasis, cellular response to starvation, chromatin modification, embryo development, endocrine pancreas development, epithelial tube branching involved in lung morphogenesis, lung epithelial cell differentiation, negative regulation of cell proliferation, neural plate anterior/posterior regionalization, neuron fate specification, positive regulation of hepatocyte differentiation, positive regulation of transcription from RNA polymerase II promoter, regulation of sequence-specific DNA binding transcription factor activity, spermatogenesis nucleus, transcription factor complex DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, protein domain specific binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding Human FOXB1 UniProtKB UniProtKB {GO:0007389=GO_REF:0000033, GO:0021510=GO_REF:0000019, GO:0033504=GO_REF:0000024, GO:0061379=GO_REF:0000024, GO:0003705=GO_REF:0000033, GO:0001756=GO_REF:0000024, GO:0001655=GO_REF:0000019, GO:0005634=GO_REF:0000024, GO:0061377=GO_REF:0000024, GO:0009790=GO_REF:0000033, GO:0061374=GO_REF:0000024, GO:0021794=GO_REF:0000019, GO:0051090=GO_REF:0000033, GO:0022029=GO_REF:0000024, GO:0007412=GO_REF:0000024, GO:0043524=GO_REF:0000024, GO:0061381=GO_REF:0000024, GO:0003690=GO_REF:0000033, GO:0009888=GO_REF:0000033, GO:0005667=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0021855=GO_REF:0000024, GO:0021767=GO_REF:0000024, GO:0043565=GO_REF:0000024, GO:0007595=GO_REF:0000024, GO:0007420=GO_REF:0000033, GO:0008542=GO_REF:0000024, GO:0030901=GO_REF:0000024, GO:0061030=GO_REF:0000024, GO:0008134=GO_REF:0000033} Q99853 Forkhead box protein B1 protein 20101123 {GO:0007389=IBA, GO:0021510=IEA, GO:0033504=ISS, GO:0061379=ISS, GO:0003705=IBA, GO:0001756=ISS, GO:0001655=IEA, GO:0005634=ISS, GO:0061377=ISS, GO:0009790=IBA, GO:0061374=ISS, GO:0021794=IEA, GO:0051090=IBA, GO:0022029=ISS, GO:0007412=ISS, GO:0043524=ISS, GO:0061381=ISS, GO:0003690=IBA, GO:0009888=IBA, GO:0005667=IBA, GO:0008301=IBA, GO:0021855=ISS, GO:0021767=ISS, GO:0043565=ISS, GO:0007595=ISS, GO:0007420=IBA, GO:0008542=ISS, GO:0030901=ISS, GO:0061030=ISS, GO:0008134=IBA} axon target recognition, brain development, cell migration in diencephalon, embryo development, epithelial cell differentiation involved in mammary gland alveolus development, floor plate development, hypothalamus cell migration, inferior colliculus development, lactation, mammary gland lobule development, mammillary body development, mammillothalamic axonal tract development, midbrain development, negative regulation of neuron apoptotic process, pattern specification process, regulation of sequence-specific DNA binding transcription factor activity, somitogenesis, spinal cord development, telencephalon cell migration, thalamus development, tissue development, urogenital system development, visual learning nucleus, transcription factor complex DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, sequence-specific DNA binding, transcription factor binding Human UniProtKB:Q64732 FOXC1 BHF-UCL UniProtKB {GO:0001656=GO_REF:0000033, GO:0005515=PMID:22190034, GO:0001657=GO_REF:0000033, GO:0003700=PMID:11179011, GO:0044212=GO_REF:0000024, GO:0055010=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0001756=GO_REF:0000033, GO:0001654=PMID:9792859, GO:0048844=GO_REF:0000033, GO:0007507=PMID:10474162, GO:0001946=GO_REF:0000033, GO:0014034=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0050880=GO_REF:0000033, GO:0007219=GO_REF:0000033, GO:0014032=GO_REF:0000019, GO:0030199=GO_REF:0000033, GO:0030203=GO_REF:0000033, GO:0008301=PMID:7957066, GO:0001701=GO_REF:0000019, GO:0031490=GO_REF:0000033, GO:0060038=GO_REF:0000033, GO:0001501=GO_REF:0000019, GO:0005720=PMID:15684392, GO:0001503=GO_REF:0000033, GO:0045930=PMID:12408963, GO:0007420=GO_REF:0000033, GO:0048343=GO_REF:0000033, GO:0045893=PMID:11237714, GO:0008134=PMID:15684392, GO:0005634=GO_REF:0000052, GO:0051090=GO_REF:0000033, GO:0005737=GO_REF:0000052, GO:0001541=GO_REF:0000033, GO:0045944=GO_REF:0000024, GO:0042475=PMID:12614756, GO:0043010=GO_REF:0000033, GO:0005667=GO_REF:0000033, GO:0046620=GO_REF:0000033, GO:0048010=GO_REF:0000033, GO:0008354=GO_REF:0000033, GO:0043066=GO_REF:0000019, GO:0006355=PMID:15684392, GO:0035050=GO_REF:0000033, GO:0005730=GO_REF:0000052, GO:0003677=PMID:11179011, GO:0043565=PMID:7957066, GO:0032808=GO_REF:0000033, GO:0001974=GO_REF:0000033, GO:0001570=GO_REF:0000033} Q12948 Forkhead box protein C1 protein 20110119 {GO:0001656=IBA, GO:0005515=IPI, GO:0001657=IBA, GO:0003700=IDA, GO:0044212=ISS, GO:0055010=IBA, GO:0003705=IBA, GO:0001756=IBA, GO:0001654=IDA, GO:0048844=IBA, GO:0007507=IDA, GO:0001946=IBA, GO:0014034=IBA, GO:0003690=IBA, GO:0050880=IBA, GO:0007219=IBA, GO:0014032=IEA, GO:0030199=IBA, GO:0030203=IBA, GO:0008301=IDA, GO:0001701=IEA, GO:0031490=IBA, GO:0060038=IBA, GO:0001501=IEA, GO:0005720=IDA, GO:0001503=IBA, GO:0045930=IDA, GO:0007420=IBA, GO:0048343=IBA, GO:0045893=IDA, GO:0008134=IPI, GO:0005634=IDA, GO:0051090=IBA, GO:0005737=IDA, GO:0001541=IBA, GO:0045944=ISS, GO:0042475=IMP, GO:0043010=IBA, GO:0005667=IBA, GO:0046620=IBA, GO:0048010=IBA, GO:0008354=IBA, GO:0043066=IEA, GO:0006355=IDA, GO:0035050=IBA, GO:0005730=IDA, GO:0003677=IDA, GO:0043565=IDA, GO:0032808=IBA, GO:0001974=IBA, GO:0001570=IBA} Notch signaling pathway, artery morphogenesis, blood vessel remodeling, brain development, camera-type eye development, cardiac muscle cell proliferation, collagen fibril organization, embryonic heart tube development, eye development, germ cell migration, glycosaminoglycan metabolic process, heart development, in utero embryonic development, lacrimal gland development, lymphangiogenesis, metanephros development, negative regulation of apoptotic process, negative regulation of mitotic cell cycle, neural crest cell development, neural crest cell fate commitment, odontogenesis of dentin-containing tooth, ossification, ovarian follicle development, paraxial mesodermal cell fate commitment, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of blood vessel size, regulation of organ growth, regulation of sequence-specific DNA binding transcription factor activity, regulation of transcription, DNA-dependent, skeletal system development, somitogenesis, ureteric bud development, vascular endothelial growth factor receptor signaling pathway, vasculogenesis, ventricular cardiac muscle tissue morphogenesis cytoplasm, nuclear heterochromatin, nucleolus, nucleus, transcription factor complex DNA binding, DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, chromatin DNA binding, double-stranded DNA binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding Human UniProtKB:Q61572 FOXC2 BHF-UCL UniProtKB {GO:0001656=GO_REF:0000033, GO:0001657=GO_REF:0000033, GO:0003700=PMID:9169153, GO:0055010=GO_REF:0000033, GO:0044212=GO_REF:0000024, GO:0003705=GO_REF:0000033, GO:0001756=GO_REF:0000033, GO:0048844=GO_REF:0000033, GO:0048703=GO_REF:0000033, GO:0007507=PMID:21457232, GO:0001946=PMID:12114478, GO:0014034=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0050880=GO_REF:0000033, GO:0014032=GO_REF:0000019, GO:0007219=GO_REF:0000033, GO:0030199=GO_REF:0000033, GO:0090050=GO_REF:0000024, GO:0008301=GO_REF:0000033, GO:0000122=GO_REF:0000024, GO:0060038=GO_REF:0000033, GO:0031490=PMID:16456100, GO:0010595=GO_REF:0000024, GO:0001503=GO_REF:0000033, GO:0035470=GO_REF:0000024, GO:0048343=GO_REF:0000033, GO:0045893=PMID:9169153, GO:0072144=GO_REF:0000019, GO:0008134=GO_REF:0000033, GO:0072011=GO_REF:0000019, GO:0008286=PMID:16456100, GO:0072112=GO_REF:0000019, GO:0005634=PMID:16081467, GO:0051090=GO_REF:0000033, GO:0045944=GO_REF:0000024, GO:0043010=GO_REF:0000033, GO:0009725=PMID:16456100, GO:0005667=GO_REF:0000033, GO:0048010=GO_REF:0000033, GO:0046620=GO_REF:0000033, GO:0043066=GO_REF:0000019, GO:0001569=GO_REF:0000033, GO:0035050=GO_REF:0000033, GO:0033630=GO_REF:0000024, GO:0043565=PMID:16081467, GO:0001077=PMID:20956529, GO:0001974=GO_REF:0000033, GO:0007498=PMID:8674414, GO:0001570=GO_REF:0000033} Q99958 Forkhead box protein C2 protein 20110119 {GO:0001656=IBA, GO:0001657=IBA, GO:0003700=IDA, GO:0055010=IBA, GO:0044212=ISS, GO:0003705=IBA, GO:0001756=IBA, GO:0048844=IBA, GO:0048703=IBA, GO:0007507=IMP, GO:0001946=IMP, GO:0014034=IBA, GO:0003690=IBA, GO:0050880=IBA, GO:0014032=IEA, GO:0007219=IBA, GO:0030199=IBA, GO:0090050=ISS, GO:0008301=IBA, GO:0000122=ISS, GO:0060038=IBA, GO:0031490=IDA, GO:0010595=ISS, GO:0001503=IBA, GO:0035470=ISS, GO:0048343=IBA, GO:0045893=IDA, GO:0072144=IEA, GO:0008134=IBA, GO:0072011=IEA, GO:0008286=IDA, GO:0072112=IEA, GO:0005634=IDA, GO:0051090=IBA, GO:0045944=ISS, GO:0043010=IBA, GO:0009725=IDA, GO:0005667=IBA, GO:0048010=IBA, GO:0046620=IBA, GO:0043066=IEA, GO:0001569=IBA, GO:0035050=IBA, GO:0033630=ISS, GO:0043565=IDA, GO:0001077=IDA, GO:0001974=IBA, GO:0007498=NAS, GO:0001570=IBA} Notch signaling pathway, artery morphogenesis, blood vessel remodeling, camera-type eye development, cardiac muscle cell proliferation, collagen fibril organization, embryonic heart tube development, embryonic viscerocranium morphogenesis, glomerular endothelium development, glomerular mesangial cell development, glomerular visceral epithelial cell differentiation, heart development, insulin receptor signaling pathway, lymphangiogenesis, mesoderm development, metanephros development, negative regulation of apoptotic process, negative regulation of transcription from RNA polymerase II promoter, neural crest cell development, neural crest cell fate commitment, ossification, paraxial mesodermal cell fate commitment, patterning of blood vessels, positive regulation of cell adhesion mediated by integrin, positive regulation of cell migration involved in sprouting angiogenesis, positive regulation of endothelial cell migration, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of vascular wound healing, regulation of blood vessel size, regulation of organ growth, regulation of sequence-specific DNA binding transcription factor activity, response to hormone stimulus, somitogenesis, ureteric bud development, vascular endothelial growth factor receptor signaling pathway, vasculogenesis, ventricular cardiac muscle tissue morphogenesis nucleus, transcription factor complex DNA binding, bending, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, chromatin DNA binding, double-stranded DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding Human UniProtKB:Q61850 FOXD3 BHF-UCL UniProtKB {GO:0005515=PMID:11891324, GO:0007389=GO_REF:0000033, GO:0000790=PMID:22306510, GO:0001658=GO_REF:0000033, GO:0003700=GO_REF:0000024, GO:0051216=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0001755=GO_REF:0000033, GO:0048846=GO_REF:0000033, GO:0051090=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0045944=PMID:11891324, GO:0005667=GO_REF:0000033, GO:0000977=PMID:22306510, GO:0008301=GO_REF:0000033, GO:0001822=GO_REF:0000033, GO:0001892=GO_REF:0000033, GO:0030318=GO_REF:0000033, GO:0000122=PMID:22306510, GO:0001829=GO_REF:0000033, GO:0001227=PMID:22306510, GO:0001701=GO_REF:0000024, GO:0048485=GO_REF:0000033, GO:0048484=GO_REF:0000033, GO:0007422=GO_REF:0000033, GO:0050935=GO_REF:0000033, GO:0048937=GO_REF:0000033, GO:0008134=GO_REF:0000033} Q9UJU5 Forkhead box protein D3 protein 20121109 {GO:0005515=IPI, GO:0007389=IBA, GO:0000790=IDA, GO:0001658=IBA, GO:0003700=ISS, GO:0051216=IBA, GO:0003705=IBA, GO:0001755=IBA, GO:0048846=IBA, GO:0051090=IBA, GO:0003690=IBA, GO:0045944=IDA, GO:0005667=IBA, GO:0000977=IDA, GO:0008301=IBA, GO:0001822=IBA, GO:0001892=IBA, GO:0030318=IBA, GO:0000122=IDA, GO:0001829=IBA, GO:0001227=IDA, GO:0001701=ISS, GO:0048485=IBA, GO:0048484=IBA, GO:0007422=IBA, GO:0050935=IBA, GO:0048937=IBA, GO:0008134=IBA} axon extension involved in axon guidance, branching involved in ureteric bud morphogenesis, cartilage development, embryonic placenta development, enteric nervous system development, in utero embryonic development, iridophore differentiation, kidney development, lateral line nerve glial cell development, melanocyte differentiation, negative regulation of transcription from RNA polymerase II promoter, neural crest cell migration, pattern specification process, peripheral nervous system development, positive regulation of transcription from RNA polymerase II promoter, regulation of sequence-specific DNA binding transcription factor activity, sympathetic nervous system development, trophectodermal cell differentiation nuclear chromatin, transcription factor complex DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, RNA polymerase II regulatory region sequence-specific DNA binding, RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, double-stranded DNA binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human FOXD4L6 HPA UniProtKB {GO:0005667=GO_REF:0000033, GO:0007389=GO_REF:0000033, GO:0090184=GO_REF:0000033, GO:0051216=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0001755=GO_REF:0000033, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0030318=GO_REF:0000033, GO:0009790=GO_REF:0000033, GO:0048846=GO_REF:0000033, GO:0048485=GO_REF:0000033, GO:0060678=GO_REF:0000033, GO:0048484=GO_REF:0000033, GO:0043565=GO_REF:0000002, GO:0051090=GO_REF:0000033, GO:0030513=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0045944=GO_REF:0000033, GO:0050935=GO_REF:0000033, GO:0007422=GO_REF:0000033, GO:0048937=GO_REF:0000033, GO:0008134=GO_REF:0000033} Q3SYB3 Forkhead box protein D4-like 6 protein 20090616 {GO:0005667=IBA, GO:0007389=IBA, GO:0090184=IBA, GO:0051216=IBA, GO:0008301=IBA, GO:0003705=IBA, GO:0001755=IBA, GO:0005730=IDA, GO:0005634=IDA, GO:0030318=IBA, GO:0009790=IBA, GO:0048846=IBA, GO:0048485=IBA, GO:0060678=IBA, GO:0048484=IBA, GO:0043565=IEA, GO:0051090=IBA, GO:0030513=IBA, GO:0003690=IBA, GO:0045944=IBA, GO:0050935=IBA, GO:0007422=IBA, GO:0048937=IBA, GO:0008134=IBA} axon extension involved in axon guidance, cartilage development, dichotomous subdivision of terminal units involved in ureteric bud branching, embryo development, enteric nervous system development, iridophore differentiation, lateral line nerve glial cell development, melanocyte differentiation, neural crest cell migration, pattern specification process, peripheral nervous system development, positive regulation of BMP signaling pathway, positive regulation of kidney development, positive regulation of transcription from RNA polymerase II promoter, regulation of sequence-specific DNA binding transcription factor activity, sympathetic nervous system development nucleolus, nucleus, transcription factor complex DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, sequence-specific DNA binding, transcription factor binding NOT Human FOXE1 UniProtKB UniProtKB {GO:0007389=GO_REF:0000033, GO:0003700=PMID:9697705, GO:0003705=GO_REF:0000033, GO:0048538=PMID:15494458, GO:0005634=PMID:9697705, GO:0030878=PMID:15494458, GO:0048846=GO_REF:0000033, GO:0009653=PMID:9169137, GO:0031069=GO_REF:0000024, GO:0051090=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0002089=GO_REF:0000033, GO:0045944=GO_REF:0000033, GO:0006590=GO_REF:0000024, GO:0060022=PMID:12165566, GO:0060023=PMID:12165566, GO:0005667=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0000122=GO_REF:0000024, GO:0003677=PMID:9697705, GO:0048485=GO_REF:0000033, GO:0048484=GO_REF:0000033, GO:0048562=GO_REF:0000024, GO:0043565=GO_REF:0000019, GO:0016477=GO_REF:0000024, GO:0060465=PMID:15494458, GO:0007422=GO_REF:0000033, GO:0048937=GO_REF:0000033, GO:0045893=PMID:9697705, GO:0045892=GO_REF:0000024, GO:0008134=GO_REF:0000033} O00358 Forkhead box protein E1 protein 20080611 {GO:0007389=IBA, GO:0003700=IDA, GO:0003705=IBA, GO:0048538=IEP, GO:0005634=IDA, GO:0030878=IEP, GO:0048846=IRD, GO:0009653=NAS, GO:0031069=ISS, GO:0051090=IBA, GO:0003690=IBA, GO:0002089=IBA, GO:0045944=IBA, GO:0006590=ISS, GO:0060022=IMP, GO:0060023=IMP, GO:0005667=IBA, GO:0008301=IBA, GO:0000122=ISS, GO:0003677=IDA, GO:0048485=IRD, GO:0048484=IRD, GO:0048562=ISS, GO:0043565=IEA, GO:0016477=ISS, GO:0060465=IEP, GO:0007422=IBA, GO:0048937=IRD, GO:0045893=IDA, GO:0045892=ISS, GO:0008134=IBA} anatomical structure morphogenesis, axon extension involved in axon guidance, cell migration, embryonic organ morphogenesis, enteric nervous system development, hair follicle morphogenesis, hard palate development, lateral line nerve glial cell development, lens morphogenesis in camera-type eye, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, pattern specification process, peripheral nervous system development, pharynx development, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of sequence-specific DNA binding transcription factor activity, soft palate development, sympathetic nervous system development, thymus development, thyroid gland development, thyroid hormone generation nucleus, transcription factor complex DNA binding, DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human UniProtKB:Q8R2I0 FOXF2 MGI UniProtKB {GO:0005667=PMID:9722567, GO:0007389=GO_REF:0000033, GO:0003700=PMID:9722567, GO:0008301=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0005634=PMID:9722567, GO:0001837=PMID:19220249, GO:0048566=GO_REF:0000019, GO:0009790=GO_REF:0000033, GO:0003677=PMID:7957066, GO:0048596=GO_REF:0000019, GO:0042249=GO_REF:0000019, GO:0043565=PMID:7957066, GO:0051090=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0030198=GO_REF:0000019, GO:0045944=PMID:8626802, GO:0009888=GO_REF:0000033, GO:0060021=PMID:19276632, GO:0048806=PMID:19276632, GO:0045893=PMID:8626802, GO:0045892=GO_REF:0000019, GO:0008134=PMID:9722567} Q12947 Forkhead box protein F2 protein 20100210 {GO:0005667=IDA, GO:0007389=IBA, GO:0003700=IDA, GO:0008301=IBA, GO:0003705=IBA, GO:0005634=IDA, GO:0001837=NAS, GO:0048566=IEA, GO:0009790=IBA, GO:0003677=IDA, GO:0048596=IEA, GO:0042249=IEA, GO:0043565=IDA, GO:0051090=IBA, GO:0003690=IBA, GO:0030198=IEA, GO:0045944=IDA, GO:0009888=IBA, GO:0060021=IMP, GO:0048806=IMP, GO:0045893=IDA, GO:0045892=IEA, GO:0008134=IPI} embryo development, embryonic camera-type eye morphogenesis, embryonic digestive tract development, epithelial to mesenchymal transition, establishment of planar polarity of embryonic epithelium, extracellular matrix organization, genitalia development, negative regulation of transcription, DNA-dependent, palate development, pattern specification process, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of sequence-specific DNA binding transcription factor activity, tissue development nucleus, transcription factor complex DNA binding, DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human FOXG1 PINC UniProtKB {GO:0005515=PMID:12657635, GO:0003705=GO_REF:0000033, GO:0005634=GO_REF:0000029, GO:0009953=GO_REF:0000033, GO:0009792=GO_REF:0000033, GO:0051090=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0016199=GO_REF:0000033, GO:0045944=GO_REF:0000033, GO:0009888=GO_REF:0000033, GO:0005667=GO_REF:0000033, GO:0006355=GO_REF:0000029, GO:0042472=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0007568=GO_REF:0000019, GO:0021954=GO_REF:0000033, GO:0002052=GO_REF:0000033, GO:0035058=GO_REF:0000033, GO:0003677=PMID:7959731, GO:0045787=GO_REF:0000033, GO:0043565=GO_REF:0000002, GO:0007346=GO_REF:0000033, GO:0045665=GO_REF:0000033, GO:0007420=PMID:7599184, GO:0030900=GO_REF:0000019, GO:0045892=PMID:12657635, GO:0030902=GO_REF:0000033, GO:0043584=GO_REF:0000033, GO:0008134=GO_REF:0000033} P55316 Forkhead box protein G1 protein 20030904 {GO:0005515=IPI, GO:0003705=IBA, GO:0005634=NAS, GO:0009953=IBA, GO:0009792=IBA, GO:0051090=IBA, GO:0003690=IBA, GO:0016199=IBA, GO:0045944=IBA, GO:0009888=IBA, GO:0005667=IBA, GO:0006355=NAS, GO:0042472=IBA, GO:0008301=IBA, GO:0007568=IEA, GO:0021954=IBA, GO:0002052=IBA, GO:0035058=IBA, GO:0003677=TAS, GO:0045787=IBA, GO:0043565=IEA, GO:0007346=IBA, GO:0045665=IBA, GO:0007420=TAS, GO:0030900=IEA, GO:0045892=IDA, GO:0030902=IBA, GO:0043584=IBA, GO:0008134=IBA} aging, axon midline choice point recognition, brain development, central nervous system neuron development, dorsal/ventral pattern formation, embryo development ending in birth or egg hatching, forebrain development, hindbrain development, inner ear morphogenesis, negative regulation of neuron differentiation, negative regulation of transcription, DNA-dependent, nonmotile primary cilium assembly, nose development, positive regulation of cell cycle, positive regulation of neuroblast proliferation, positive regulation of transcription from RNA polymerase II promoter, regulation of mitotic cell cycle, regulation of sequence-specific DNA binding transcription factor activity, regulation of transcription, DNA-dependent, tissue development nucleus, transcription factor complex DNA binding, DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, protein binding, sequence-specific DNA binding, transcription factor binding Human FOXH1 BHF-UCL UniProtKB {GO:0005515=PMID:17474147, GO:0003700=PMID:17438144, GO:0001190=GO_REF:0000019, GO:0044212=GO_REF:0000024, GO:0003705=GO_REF:0000033, GO:0003139=GO_REF:0000019, GO:0005634=PMID:16120611, GO:0003215=GO_REF:0000019, GO:0050681=PMID:16120611, GO:0001947=GO_REF:0000033, GO:0051090=GO_REF:0000033, GO:0042074=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0003146=GO_REF:0000033, GO:0045944=PMID:9702198, GO:1900164=PMID:17507406, GO:0003222=GO_REF:0000019, GO:0007179=GO_REF:0000024, GO:0010159=GO_REF:0000033, GO:0005667=PMID:17438144, GO:0048318=GO_REF:0000033, GO:0001568=GO_REF:0000033, GO:0001104=GO_REF:0000019, GO:0008301=GO_REF:0000033, GO:0019904=PMID:9702198, GO:0070410=PMID:16120611, GO:0035909=GO_REF:0000019, GO:0035054=GO_REF:0000033, GO:0060766=PMID:16120611, GO:0021508=GO_REF:0000033, GO:0070412=PMID:16120611, GO:2000824=PMID:16120611, GO:0003677=PMID:9389648, GO:0003151=GO_REF:0000019, GO:0032444=PMID:9389648, GO:0043565=PMID:9702198, GO:0005654=Reactome:REACT_111132, GO:0033147=PMID:16120611, GO:0045893=PMID:9389648, GO:0008134=GO_REF:0000033} O75593 Forkhead box protein H1 protein 20120516 {GO:0005515=IPI, GO:0003700=IDA, GO:0001190=IEA, GO:0044212=ISS, GO:0003705=IBA, GO:0003139=IEA, GO:0005634=IDA, GO:0003215=IEA, GO:0050681=IPI, GO:0001947=IBA, GO:0051090=IBA, GO:0042074=IBA, GO:0003690=IBA, GO:0003146=IRD, GO:0045944=IDA, GO:1900164=NAS, GO:0003222=IEA, GO:0007179=ISS, GO:0010159=IBA, GO:0005667=IDA, GO:0048318=IBA, GO:0001568=IBA, GO:0001104=IEA, GO:0008301=IBA, GO:0019904=IPI, GO:0070410=IMP, GO:0035909=IEA, GO:0035054=IBA, GO:0060766=IDA, GO:0021508=IBA, GO:0070412=IMP, GO:2000824=IDA, GO:0003677=IDA, GO:0003151=IEA, GO:0032444=IDA, GO:0043565=IDA, GO:0005654=TAS, GO:0033147=IDA, GO:0045893=IDA, GO:0008134=IBA} aorta morphogenesis, axial mesoderm development, blood vessel development, cardiac right ventricle morphogenesis, cell migration involved in gastrulation, embryonic heart tube anterior/posterior pattern specification, floor plate formation, heart jogging, heart looping, negative regulation of androgen receptor activity, negative regulation of androgen receptor signaling pathway, negative regulation of intracellular estrogen receptor signaling pathway, nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry, outflow tract morphogenesis, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of sequence-specific DNA binding transcription factor activity, secondary heart field specification, specification of organ position, transforming growth factor beta receptor signaling pathway, ventricular trabecula myocardium morphogenesis activin responsive factor complex, nucleoplasm, nucleus, transcription factor complex DNA binding, DNA binding, bending, R-SMAD binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, RNA polymerase II transcription cofactor activity, RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription, androgen receptor binding, co-SMAD binding, double-stranded DNA binding, protein binding, protein domain specific binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding Human UniProtKB:P10275 FOXI1 UniProtKB UniProtKB {GO:0005667=GO_REF:0000033, GO:0007389=GO_REF:0000033, GO:0003700=PMID:19214237, GO:0044212=GO_REF:0000024, GO:0008301=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0005634=PMID:19214237, GO:0009790=PMID:7957066, GO:0043565=GO_REF:0000024, GO:0051090=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0009957=GO_REF:0000033, GO:0045944=PMID:19214237, GO:0043049=GO_REF:0000033, GO:0008134=GO_REF:0000033} Q12951 Forkhead box protein I1 protein 20100415 {GO:0005667=IBA, GO:0007389=IBA, GO:0003700=IDA, GO:0044212=ISS, GO:0008301=IBA, GO:0003705=IBA, GO:0005634=IC, GO:0009790=NAS, GO:0043565=ISS, GO:0051090=IBA, GO:0003690=IBA, GO:0009957=IBA, GO:0045944=IDA, GO:0043049=IBA, GO:0008134=IBA} embryo development, epidermal cell fate specification, otic placode formation, pattern specification process, positive regulation of transcription from RNA polymerase II promoter, regulation of sequence-specific DNA binding transcription factor activity nucleus, transcription factor complex DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding Human UniProtKB:Q922I5 FOXJ1 BHF-UCL UniProtKB {GO:0007389=GO_REF:0000024, GO:1901248=PMID:20539013, GO:0060428=PMID:9530170, GO:0030036=GO_REF:0000024, GO:0003700=PMID:9073514, GO:0030324=GO_REF:0000033, GO:0033085=GO_REF:0000024, GO:0003705=GO_REF:0000033, GO:0035089=GO_REF:0000024, GO:0045409=GO_REF:0000024, GO:0005634=PMID:17008636, GO:0072016=PMID:9530170, GO:0007283=PMID:9073514, GO:0050900=GO_REF:0000024, GO:0042130=GO_REF:0000033, GO:0001947=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0060972=GO_REF:0000033, GO:0045944=PMID:9096351, GO:0006959=GO_REF:0000024, GO:0030855=GO_REF:0000033, GO:0002635=GO_REF:0000024, GO:0002924=GO_REF:0000024, GO:0005667=GO_REF:0000033, GO:0000976=PMID:9096351, GO:0008301=GO_REF:0000033, GO:0050869=GO_REF:0000024, GO:0019904=GO_REF:0000033, GO:0035502=PMID:9530170, GO:0002508=GO_REF:0000024, GO:0032088=GO_REF:0000024, GO:0000122=GO_REF:0000024, GO:0032862=GO_REF:0000024, GO:0002897=GO_REF:0000024, GO:0003677=PMID:9073514, GO:0042384=GO_REF:0000024, GO:0007420=PMID:9096351, GO:0008134=GO_REF:0000033} Q92949 Forkhead box protein J1 protein 20120808 {GO:0007389=ISS, GO:1901248=IDA, GO:0060428=IEP, GO:0030036=ISS, GO:0003700=NAS, GO:0030324=IBA, GO:0033085=ISS, GO:0003705=IBA, GO:0035089=ISS, GO:0045409=ISS, GO:0005634=IDA, GO:0072016=IEP, GO:0007283=NAS, GO:0050900=ISS, GO:0042130=IBA, GO:0001947=IBA, GO:0003690=IBA, GO:0060972=IBA, GO:0045944=IDA, GO:0006959=ISS, GO:0030855=IBA, GO:0002635=ISS, GO:0002924=ISS, GO:0005667=IBA, GO:0000976=IDA, GO:0008301=IBA, GO:0050869=ISS, GO:0019904=IBA, GO:0035502=IEP, GO:0002508=ISS, GO:0032088=ISS, GO:0000122=ISS, GO:0032862=ISS, GO:0002897=ISS, GO:0003677=NAS, GO:0042384=ISS, GO:0007420=NAS, GO:0008134=IBA} actin cytoskeleton organization, activation of Rho GTPase activity, brain development, central tolerance induction, cilium assembly, epithelial cell differentiation, establishment of apical/basal cell polarity, glomerular parietal epithelial cell development, heart looping, humoral immune response, left/right pattern formation, leukocyte migration, lung development, lung epithelium development, metanephric part of ureteric bud development, negative regulation of B cell activation, negative regulation of NF-kappaB transcription factor activity, negative regulation of T cell differentiation in thymus, negative regulation of T cell proliferation, negative regulation of germinal center formation, negative regulation of humoral immune response mediated by circulating immunoglobulin, negative regulation of interleukin-6 biosynthetic process, negative regulation of transcription from RNA polymerase II promoter, pattern specification process, positive regulation of central B cell tolerance induction, positive regulation of lung ciliated cell differentiation, positive regulation of transcription from RNA polymerase II promoter, spermatogenesis nucleus, transcription factor complex DNA binding, DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, protein domain specific binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region sequence-specific DNA binding Human FOXJ2 HPA UniProtKB {GO:0005667=GO_REF:0000033, GO:0007389=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0019904=GO_REF:0000033, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0009790=GO_REF:0000033, GO:0048513=GO_REF:0000033, GO:0043565=GO_REF:0000002, GO:0051090=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0009888=GO_REF:0000033, GO:0008134=GO_REF:0000033} Q9P0K8 Forkhead box protein J2 protein 20101115 {GO:0005667=IBA, GO:0007389=IBA, GO:0008301=IBA, GO:0003705=IBA, GO:0019904=IBA, GO:0005730=IDA, GO:0005634=IDA, GO:0009790=IBA, GO:0048513=IBA, GO:0043565=IEA, GO:0051090=IBA, GO:0003690=IBA, GO:0009888=IBA, GO:0008134=IBA} embryo development, organ development, pattern specification process, regulation of sequence-specific DNA binding transcription factor activity, tissue development nucleolus, nucleus, transcription factor complex DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, protein domain specific binding, sequence-specific DNA binding, transcription factor binding Human FOXJ3 RefGenome UniProtKB {GO:0005667=GO_REF:0000033, GO:0007389=GO_REF:0000033, GO:0003700=GO_REF:0000002, GO:0008301=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0019904=GO_REF:0000033, GO:0005634=GO_REF:0000038, GO:0048513=GO_REF:0000033, GO:0009790=GO_REF:0000033, GO:0006351=GO_REF:0000038, GO:0043565=GO_REF:0000002, GO:0051090=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0009888=GO_REF:0000033, GO:0045893=GO_REF:0000033, GO:0008134=GO_REF:0000033} Q9UPW0 Forkhead box protein J3 protein 20100514 {GO:0005667=IBA, GO:0007389=IBA, GO:0003700=IEA, GO:0008301=IBA, GO:0003705=IBA, GO:0019904=IBA, GO:0005634=IEA, GO:0048513=IBA, GO:0009790=IBA, GO:0006351=IEA, GO:0043565=IEA, GO:0051090=IBA, GO:0003690=IBA, GO:0009888=IBA, GO:0045893=IBA, GO:0008134=IBA} embryo development, organ development, pattern specification process, positive regulation of transcription, DNA-dependent, regulation of sequence-specific DNA binding transcription factor activity, tissue development, transcription, DNA-dependent nucleus, transcription factor complex DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, protein domain specific binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human PANTHER:PTN000215024 FOXK1 HPA UniProtKB {GO:0005515=PMID:21903422, GO:0005667=GO_REF:0000033, GO:0007389=GO_REF:0000033, GO:0030308=GO_REF:0000019, GO:0000287=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0009790=GO_REF:0000033, GO:0030154=GO_REF:0000037, GO:0043565=GO_REF:0000019, GO:0051090=GO_REF:0000033, GO:0007517=GO_REF:0000037, GO:0003690=GO_REF:0000033, GO:0009888=GO_REF:0000033, GO:0045893=GO_REF:0000019, GO:0045892=GO_REF:0000019, GO:0008134=GO_REF:0000033} P85037 Forkhead box protein K1 protein 20101115 {GO:0005515=IPI, GO:0005667=IBA, GO:0007389=IBA, GO:0030308=IEA, GO:0000287=IBA, GO:0008301=IBA, GO:0003705=IBA, GO:0005730=IDA, GO:0005634=IDA, GO:0009790=IBA, GO:0030154=IEA, GO:0043565=IEA, GO:0051090=IBA, GO:0007517=IEA, GO:0003690=IBA, GO:0009888=IBA, GO:0045893=IEA, GO:0045892=IEA, GO:0008134=IBA} cell differentiation, embryo development, muscle organ development, negative regulation of cell growth, negative regulation of transcription, DNA-dependent, pattern specification process, positive regulation of transcription, DNA-dependent, regulation of sequence-specific DNA binding transcription factor activity, tissue development nucleolus, nucleus, transcription factor complex DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, magnesium ion binding, protein binding, sequence-specific DNA binding, transcription factor binding NOT Human FOXK2 HPA UniProtKB {GO:0005515=PMID:21903422, GO:0005667=GO_REF:0000033, GO:0007389=GO_REF:0000033, GO:0006355=PMID:12402362, GO:0000287=PMID:16624804, GO:0003700=PMID:12402362, GO:0006357=PMID:1909027, GO:0008301=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0009790=GO_REF:0000033, GO:0006351=GO_REF:0000038, GO:0043231=GO_REF:0000052, GO:0043565=PMID:12402362, GO:0051090=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0009888=GO_REF:0000033, GO:0008134=GO_REF:0000033} Q01167 Forkhead box protein K2 protein 20100326 {GO:0005515=IPI, GO:0005667=IBA, GO:0007389=IBA, GO:0006355=NAS, GO:0000287=IDA, GO:0003700=NAS, GO:0006357=TAS, GO:0008301=IBA, GO:0003705=IBA, GO:0005730=IDA, GO:0005634=IDA, GO:0009790=IBA, GO:0006351=IEA, GO:0043231=IDA, GO:0043565=IDA, GO:0051090=IBA, GO:0003690=IBA, GO:0009888=IBA, GO:0008134=IBA} embryo development, pattern specification process, regulation of sequence-specific DNA binding transcription factor activity, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, tissue development, transcription, DNA-dependent intracellular membrane-bounded organelle, nucleolus, nucleus, transcription factor complex DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, magnesium ion binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human FOXL1 MGI UniProtKB {GO:0035136=GO_REF:0000033, GO:0005667=GO_REF:0000033, GO:0007389=GO_REF:0000033, GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000024, GO:0030111=GO_REF:0000024, GO:0051216=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0005634=PMID:7957066, GO:0007275=PMID:11078474, GO:0009790=GO_REF:0000033, GO:0003677=PMID:7957066, GO:0030166=GO_REF:0000024, GO:0043565=PMID:7957066, GO:0007507=PMID:21457232, GO:0051090=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0007420=GO_REF:0000033, GO:0007495=GO_REF:0000024, GO:0009887=GO_REF:0000024, GO:0043010=GO_REF:0000033, GO:0008134=GO_REF:0000033} Q12952 Forkhead box protein L1 protein 20061227 {GO:0035136=IBA, GO:0005667=IBA, GO:0007389=IBA, GO:0006355=NAS, GO:0003700=ISS, GO:0030111=ISS, GO:0051216=IBA, GO:0008301=IBA, GO:0003705=IBA, GO:0005634=IC, GO:0007275=NAS, GO:0009790=IBA, GO:0003677=IDA, GO:0030166=ISS, GO:0043565=IDA, GO:0007507=IMP, GO:0051090=IBA, GO:0003690=IBA, GO:0007420=IBA, GO:0007495=ISS, GO:0009887=ISS, GO:0043010=IBA, GO:0008134=IBA} brain development, camera-type eye development, cartilage development, embryo development, forelimb morphogenesis, heart development, multicellular organismal development, organ morphogenesis, pattern specification process, proteoglycan biosynthetic process, regulation of Wnt receptor signaling pathway, regulation of sequence-specific DNA binding transcription factor activity, regulation of transcription, DNA-dependent, visceral mesoderm-endoderm interaction involved in midgut development nucleus, transcription factor complex DNA binding, DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human FOXL2 UniProtKB UniProtKB {GO:0005515=PMID:16153597, GO:0007389=GO_REF:0000033, GO:0003700=PMID:12471206, GO:0003705=GO_REF:0000033, GO:0042703=PMID:12161610, GO:0005634=PMID:12471206, GO:0030154=PMID:12471206, GO:0051090=GO_REF:0000033, GO:0060026=GO_REF:0000033, GO:0001541=GO_REF:0000024, GO:0003690=GO_REF:0000033, GO:0045944=GO_REF:0000033, GO:0031624=PMID:19744555, GO:0048048=GO_REF:0000033, GO:0043028=PMID:16153597, GO:0005667=GO_REF:0000033, GO:0043065=PMID:16153597, GO:0008301=GO_REF:0000033, GO:0030331=GO_REF:0000033, GO:0006917=GO_REF:0000033, GO:0003677=PMID:11175783, GO:0043280=PMID:16153597, GO:0043565=GO_REF:0000002, GO:0019101=GO_REF:0000033, GO:0006309=PMID:16153597, GO:0002074=PMID:12630957, GO:0045893=GO_REF:0000024, GO:0045892=PMID:19744555, GO:0060014=GO_REF:0000019, GO:0008134=GO_REF:0000033} P58012 Forkhead box protein L2 protein 20091221 {GO:0005515=IPI, GO:0007389=IBA, GO:0003700=NAS, GO:0003705=IBA, GO:0042703=IMP, GO:0005634=IDA, GO:0030154=NAS, GO:0051090=IBA, GO:0060026=IBA, GO:0001541=ISS, GO:0003690=IBA, GO:0045944=IBA, GO:0031624=IPI, GO:0048048=IBA, GO:0043028=IMP, GO:0005667=IBA, GO:0043065=IMP, GO:0008301=IBA, GO:0030331=IBA, GO:0006917=IBA, GO:0003677=TAS, GO:0043280=IMP, GO:0043565=IEA, GO:0019101=IBA, GO:0006309=IMP, GO:0002074=IMP, GO:0045893=ISS, GO:0045892=IDA, GO:0060014=IEA, GO:0008134=IBA} apoptotic DNA fragmentation, cell differentiation, convergent extension, embryonic eye morphogenesis, extraocular skeletal muscle development, female somatic sex determination, granulosa cell differentiation, induction of apoptosis, menstruation, negative regulation of transcription, DNA-dependent, ovarian follicle development, pattern specification process, positive regulation of apoptotic process, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of sequence-specific DNA binding transcription factor activity nucleus, transcription factor complex DNA binding, DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, cysteine-type endopeptidase regulator activity involved in apoptotic process, double-stranded DNA binding, estrogen receptor binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, ubiquitin conjugating enzyme binding Human UniProtKB:P63279 FOXM1 BHF-UCL UniProtKB {GO:0071156=PMID:19696738, GO:0005515=PMID:16809346, GO:0007389=GO_REF:0000033, GO:0008284=PMID:19696738, GO:0003700=GO_REF:0000002, GO:0044212=GO_REF:0000019, GO:0003705=GO_REF:0000033, GO:0090344=PMID:19696738, GO:0005634=GO_REF:0000052, GO:0046578=PMID:19696738, GO:0009790=GO_REF:0000033, GO:0032873=PMID:19696738, GO:0051090=GO_REF:0000033, GO:0005737=GO_REF:0000052, GO:0003690=GO_REF:0000033, GO:0045944=PMID:20531406, GO:0000086=PMID:19160488, GO:0009888=GO_REF:0000033, GO:0006978=PMID:17101782, GO:0005667=GO_REF:0000033, GO:0019901=PMID:19160488, GO:0008301=GO_REF:0000033, GO:0019904=GO_REF:0000033, GO:0005730=GO_REF:0000052, GO:0000122=PMID:20531406, GO:0001889=GO_REF:0000033, GO:0043565=GO_REF:0000002, GO:0006281=GO_REF:0000037, GO:2000377=PMID:19696738, GO:2000781=PMID:17101782, GO:0045893=PMID:20531406, GO:0001570=GO_REF:0000033, GO:0045892=PMID:20531406, GO:0008134=GO_REF:0000033} Q08050 Forkhead box protein M1 protein 20110418 {GO:0071156=IMP, GO:0005515=IPI, GO:0007389=IBA, GO:0008284=IMP, GO:0003700=IEA, GO:0044212=IEA, GO:0003705=IBA, GO:0090344=IMP, GO:0005634=IDA, GO:0046578=IMP, GO:0009790=IBA, GO:0032873=IMP, GO:0051090=IBA, GO:0005737=IDA, GO:0003690=IBA, GO:0045944=IMP, GO:0000086=IDA, GO:0009888=IBA, GO:0006978=IMP, GO:0005667=IBA, GO:0019901=IPI, GO:0008301=IBA, GO:0019904=IBA, GO:0005730=IDA, GO:0000122=IMP, GO:0001889=IBA, GO:0043565=IEA, GO:0006281=IEA, GO:2000377=IMP, GO:2000781=IMP, GO:0045893=IMP, GO:0001570=IBA, GO:0045892=IMP, GO:0008134=IBA} DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, DNA repair, G2/M transition of mitotic cell cycle, embryo development, liver development, negative regulation of cell aging, negative regulation of stress-activated MAPK cascade, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, pattern specification process, positive regulation of cell proliferation, positive regulation of double-strand break repair, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of Ras protein signal transduction, regulation of cell cycle arrest, regulation of reactive oxygen species metabolic process, regulation of sequence-specific DNA binding transcription factor activity, tissue development, vasculogenesis cytoplasm, nucleolus, nucleus, transcription factor complex DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, protein binding, protein domain specific binding, protein kinase binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding Human FOXN2 HPA UniProtKB {GO:0005667=GO_REF:0000033, GO:0007389=GO_REF:0000033, GO:0003700=PMID:1639393, GO:0008301=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0005634=GO_REF:0000052, GO:0009790=GO_REF:0000033, GO:0006351=GO_REF:0000038, GO:0043231=GO_REF:0000052, GO:0043565=GO_REF:0000002, GO:0051090=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0009888=GO_REF:0000033, GO:0008134=GO_REF:0000033} P32314 Forkhead box protein N2 protein 20101115 {GO:0005667=IBA, GO:0007389=IBA, GO:0003700=TAS, GO:0008301=IBA, GO:0003705=IBA, GO:0005634=IDA, GO:0009790=IBA, GO:0006351=IEA, GO:0043231=IDA, GO:0043565=IEA, GO:0051090=IBA, GO:0003690=IBA, GO:0009888=IBA, GO:0008134=IBA} embryo development, pattern specification process, regulation of sequence-specific DNA binding transcription factor activity, tissue development, transcription, DNA-dependent intracellular membrane-bounded organelle, nucleus, transcription factor complex DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human FOXN3 IntAct UniProtKB {GO:0005515=PMID:16102918, GO:0005667=GO_REF:0000033, GO:0007389=GO_REF:0000033, GO:0003700=GO_REF:0000002, GO:0008301=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0005634=PMID:16102918, GO:0009790=GO_REF:0000033, GO:0008022=PMID:16951149, GO:0006351=GO_REF:0000038, GO:0043565=GO_REF:0000002, GO:0000085=PMID:9154802, GO:0051090=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0009888=GO_REF:0000033, GO:0000077=PMID:9154802, GO:0045892=PMID:16102918, GO:0008134=GO_REF:0000033} O00409 Forkhead box protein N3 protein 20130415 {GO:0005515=IPI, GO:0005667=IBA, GO:0007389=IBA, GO:0003700=IEA, GO:0008301=IBA, GO:0003705=IBA, GO:0005634=IC, GO:0009790=IBA, GO:0008022=IPI, GO:0006351=IEA, GO:0043565=IEA, GO:0000085=TAS, GO:0051090=IBA, GO:0003690=IBA, GO:0009888=IBA, GO:0000077=TAS, GO:0045892=IDA, GO:0008134=IBA} DNA damage checkpoint, G2 phase of mitotic cell cycle, embryo development, negative regulation of transcription, DNA-dependent, pattern specification process, regulation of sequence-specific DNA binding transcription factor activity, tissue development, transcription, DNA-dependent nucleus, transcription factor complex DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, protein C-terminus binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human UniProtKB:Q13573 FOXO1 BHF-UCL UniProtKB {GO:0005515=PMID:18408765, GO:0008286=GO_REF:0000024, GO:0007389=GO_REF:0000033, GO:0001659=PMID:22510882, GO:0001678=PMID:22510882, GO:0071732=GO_REF:0000024, GO:0045599=GO_REF:0000024, GO:0003705=GO_REF:0000033, GO:0005634=GO_REF:0000052, GO:0009790=GO_REF:0000033, GO:0048513=GO_REF:0000033, GO:0032873=PMID:19696738, GO:0005829=Reactome:REACT_13699, GO:0005739=PMID:22510882, GO:0051090=GO_REF:0000033, GO:0005737=PMID:11237865, GO:0003690=GO_REF:0000033, GO:0007173=Reactome:REACT_9417, GO:0045944=PMID:12228231, GO:0042127=GO_REF:0000033, GO:0009888=GO_REF:0000033, GO:0045444=PMID:22510882, GO:0051721=GO_REF:0000024, GO:0006473=PMID:22510882, GO:0009267=PMID:22510882, GO:0005667=GO_REF:0000033, GO:0048011=Reactome:REACT_11061, GO:0043066=PMID:10871843, GO:0001568=GO_REF:0000033, GO:0019901=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0048015=Reactome:REACT_12464, GO:0045722=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0006974=GO_REF:0000024, GO:0070417=PMID:22510882, GO:0043565=PMID:12228231, GO:0001078=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0031018=Reactome:REACT_13819, GO:0003682=PMID:22510882, GO:0005654=Reactome:REACT_147827, GO:0034599=GO_REF:0000024, GO:0045893=PMID:12228231, GO:2000505=PMID:22510882, GO:0045892=PMID:22510882, GO:0008134=GO_REF:0000033} Q12778 Forkhead box protein O1 protein 20100202 {GO:0005515=IPI, GO:0008286=ISS, GO:0007389=IBA, GO:0001659=ISS, GO:0001678=ISS, GO:0071732=ISS, GO:0045599=ISS, GO:0003705=IBA, GO:0005634=IDA, GO:0009790=IBA, GO:0048513=IBA, GO:0032873=IDA, GO:0005829=TAS, GO:0005739=ISS, GO:0051090=IBA, GO:0005737=IDA, GO:0003690=IBA, GO:0007173=TAS, GO:0045944=IDA, GO:0042127=IBA, GO:0009888=IBA, GO:0045444=ISS, GO:0051721=ISS, GO:0006473=ISS, GO:0009267=ISS, GO:0005667=IBA, GO:0048011=TAS, GO:0043066=IDA, GO:0001568=IBA, GO:0019901=IBA, GO:0008301=IBA, GO:0048015=TAS, GO:0045722=IEA, GO:0006915=IEA, GO:0006974=ISS, GO:0070417=ISS, GO:0043565=IDA, GO:0001078=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:0031018=TAS, GO:0003682=ISS, GO:0005654=TAS, GO:0034599=ISS, GO:0045893=IDA, GO:2000505=ISS, GO:0045892=ISS, GO:0008134=IBA} apoptotic process, blood vessel development, cellular glucose homeostasis, cellular response to cold, cellular response to nitric oxide, cellular response to oxidative stress, cellular response to starvation, embryo development, endocrine pancreas development, epidermal growth factor receptor signaling pathway, fat cell differentiation, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, negative regulation of apoptotic process, negative regulation of fat cell differentiation, negative regulation of stress-activated MAPK cascade, negative regulation of transcription, DNA-dependent, neurotrophin TRK receptor signaling pathway, organ development, pattern specification process, phosphatidylinositol-mediated signaling, positive regulation of gluconeogenesis, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein acetylation, regulation of cell proliferation, regulation of energy homeostasis, regulation of sequence-specific DNA binding transcription factor activity, response to DNA damage stimulus, temperature homeostasis, tissue development cytoplasm, cytosol, mitochondrion, nucleoplasm, nucleus, transcription factor complex DNA binding, bending, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, chromatin binding, double-stranded DNA binding, protein binding, protein kinase binding, protein phosphatase 2A binding, sequence-specific DNA binding, transcription factor binding Human FOXO3 BHF-UCL UniProtKB {GO:0005515=PMID:21909281, GO:0008286=GO_REF:0000033, GO:0007389=GO_REF:0000033, GO:0003700=PMID:14734530, GO:0003705=GO_REF:0000033, GO:0005634=PMID:22761832, GO:0001556=GO_REF:0000033, GO:0009790=GO_REF:0000033, GO:0005829=GO_REF:0000033, GO:0051090=GO_REF:0000033, GO:0005737=PMID:21329882, GO:0003690=GO_REF:0000033, GO:0007173=Reactome:REACT_9417, GO:0045944=PMID:14734530, GO:0042127=GO_REF:0000033, GO:0009888=GO_REF:0000033, GO:0005667=GO_REF:0000033, GO:0048011=Reactome:REACT_11061, GO:0019901=PMID:21329882, GO:0030330=GO_REF:0000019, GO:0008301=GO_REF:0000033, GO:0048015=Reactome:REACT_12464, GO:0006950=PMID:21329882, GO:0001544=GO_REF:0000033, GO:0006915=PMID:10102273, GO:0001542=GO_REF:0000033, GO:0000122=PMID:18787191, GO:0042593=GO_REF:0000033, GO:0006917=GO_REF:0000033, GO:0003677=PMID:21329882, GO:0006417=PMID:21329882, GO:0006974=GO_REF:0000033, GO:0001547=GO_REF:0000033, GO:0043565=PMID:10102273, GO:0016020=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0045648=PMID:14734530, GO:0045087=Reactome:REACT_6802, GO:0005654=Reactome:REACT_147827, GO:0045893=PMID:10102273, GO:0008134=GO_REF:0000033} O43524 Forkhead box protein O3 protein 20100520 {GO:0005515=IPI, GO:0008286=IBA, GO:0007389=IBA, GO:0003700=IDA, GO:0003705=IBA, GO:0005634=IDA, GO:0001556=IBA, GO:0009790=IBA, GO:0005829=IBA, GO:0051090=IBA, GO:0005737=IDA, GO:0003690=IBA, GO:0007173=TAS, GO:0045944=IDA, GO:0042127=IBA, GO:0009888=IBA, GO:0005667=IBA, GO:0048011=TAS, GO:0019901=IPI, GO:0030330=IEA, GO:0008301=IBA, GO:0048015=TAS, GO:0006950=IDA, GO:0001544=IBA, GO:0006915=IDA, GO:0001542=IBA, GO:0000122=IMP, GO:0042593=IBA, GO:0006917=IBA, GO:0003677=IDA, GO:0006417=IDA, GO:0006974=IBA, GO:0001547=IBA, GO:0043565=IDA, GO:0016020=IEA, GO:0008543=TAS, GO:0045648=IDA, GO:0045087=TAS, GO:0005654=TAS, GO:0045893=IDA, GO:0008134=IBA} DNA damage response, signal transduction by p53 class mediator, antral ovarian follicle growth, apoptotic process, embryo development, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, glucose homeostasis, induction of apoptosis, initiation of primordial ovarian follicle growth, innate immune response, insulin receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, neurotrophin TRK receptor signaling pathway, oocyte maturation, ovulation from ovarian follicle, pattern specification process, phosphatidylinositol-mediated signaling, positive regulation of erythrocyte differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of cell proliferation, regulation of sequence-specific DNA binding transcription factor activity, regulation of translation, response to DNA damage stimulus, response to stress, tissue development cytoplasm, cytosol, membrane, nucleoplasm, nucleus, transcription factor complex DNA binding, DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, protein binding, protein kinase binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human FOXO4 IntAct UniProtKB {GO:0007095=GO_REF:0000033, GO:0005515=PMID:15126506, GO:0008286=PMID:10217147, GO:0007389=GO_REF:0000033, GO:0008285=PMID:10783894, GO:0003700=PMID:10783894, GO:0006366=PMID:10783894, GO:0003705=GO_REF:0000033, GO:0005634=PMID:22972301, GO:0048513=GO_REF:0000033, GO:0009790=GO_REF:0000033, GO:0005829=PMID:22972301, GO:0051090=GO_REF:0000033, GO:0005737=PMID:16964248, GO:0003690=GO_REF:0000033, GO:0007173=Reactome:REACT_9417, GO:0045944=GO_REF:0000033, GO:0009888=GO_REF:0000033, GO:0007050=PMID:10783894, GO:0000080=PMID:10783894, GO:0005667=GO_REF:0000033, GO:0048011=Reactome:REACT_11061, GO:0006355=PMID:15126506, GO:0019901=GO_REF:0000033, GO:0051151=PMID:16054032, GO:0008301=GO_REF:0000033, GO:0048015=Reactome:REACT_12464, GO:0003677=PMID:10783894, GO:0048863=PMID:22972301, GO:0043565=PMID:22972301, GO:0007517=GO_REF:0000037, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0016525=PMID:12761217, GO:0001071=PMID:22972301, GO:0005654=Reactome:REACT_147827, GO:0019899=PMID:16964248, GO:0008134=PMID:16054032} P98177 Forkhead box protein O4 protein 20130415 {GO:0007095=IBA, GO:0005515=IPI, GO:0008286=IDA, GO:0007389=IBA, GO:0008285=IDA, GO:0003700=IDA, GO:0006366=TAS, GO:0003705=IBA, GO:0005634=TAS, GO:0048513=IBA, GO:0009790=IBA, GO:0005829=TAS, GO:0051090=IBA, GO:0005737=IDA, GO:0003690=IBA, GO:0007173=TAS, GO:0045944=IBA, GO:0009888=IBA, GO:0007050=IDA, GO:0000080=IDA, GO:0005667=IBA, GO:0048011=TAS, GO:0006355=IDA, GO:0019901=IBA, GO:0051151=IDA, GO:0008301=IBA, GO:0048015=TAS, GO:0003677=IDA, GO:0048863=IMP, GO:0043565=IMP, GO:0007517=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:0016525=IDA, GO:0001071=IMP, GO:0005654=TAS, GO:0019899=IPI, GO:0008134=IPI} G1 phase of mitotic cell cycle, cell cycle arrest, embryo development, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, mitotic G2 DNA damage checkpoint, muscle organ development, negative regulation of angiogenesis, negative regulation of cell proliferation, negative regulation of smooth muscle cell differentiation, neurotrophin TRK receptor signaling pathway, organ development, pattern specification process, phosphatidylinositol-mediated signaling, positive regulation of transcription from RNA polymerase II promoter, regulation of sequence-specific DNA binding transcription factor activity, regulation of transcription, DNA-dependent, stem cell differentiation, tissue development, transcription from RNA polymerase II promoter cytoplasm, cytosol, nucleoplasm, nucleus, transcription factor complex DNA binding, DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, enzyme binding, nucleic acid binding transcription factor activity, protein binding, protein kinase binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human UniProtKB:Q96EB6 FOXP1 HPA UniProtKB {GO:0007389=GO_REF:0000033, GO:0003700=GO_REF:0000002, GO:0030324=GO_REF:0000019, GO:0003705=GO_REF:0000033, GO:0060043=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0009790=GO_REF:0000033, GO:0021517=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0042803=GO_REF:0000033, GO:0051090=GO_REF:0000033, GO:0005737=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0002639=GO_REF:0000033, GO:0060501=GO_REF:0000033, GO:0045944=GO_REF:0000019, GO:0048745=GO_REF:0000033, GO:0002329=GO_REF:0000033, GO:0055007=GO_REF:0000033, GO:0050679=GO_REF:0000019, GO:0005667=GO_REF:0000033, GO:0033152=GO_REF:0000033, GO:0046982=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0005730=GO_REF:0000052, GO:0045214=GO_REF:0000019, GO:0002053=GO_REF:0000033, GO:0003677=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:2000727=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0008045=GO_REF:0000019, GO:0007519=GO_REF:0000033, GO:0003682=GO_REF:0000033, GO:0045892=PMID:20950788, GO:0008134=GO_REF:0000033} Q9H334 Forkhead box protein P1 protein 20080205 {GO:0007389=IBA, GO:0003700=IEA, GO:0030324=IEA, GO:0003705=IBA, GO:0060043=IEA, GO:0005634=IDA, GO:0009790=IBA, GO:0021517=IEA, GO:0046872=IEA, GO:0042803=IBA, GO:0051090=IBA, GO:0005737=IBA, GO:0003690=IBA, GO:0002639=IBA, GO:0060501=IBA, GO:0045944=IEA, GO:0048745=IBA, GO:0002329=IBA, GO:0055007=IBA, GO:0050679=IEA, GO:0005667=IBA, GO:0033152=IBA, GO:0046982=IBA, GO:0008301=IBA, GO:0005730=IDA, GO:0045214=IEA, GO:0002053=IBA, GO:0003677=IEA, GO:0001701=IEA, GO:2000727=IEA, GO:0043565=IEA, GO:0008045=IEA, GO:0007519=IBA, GO:0003682=IBA, GO:0045892=IDA, GO:0008134=IBA} cardiac muscle cell differentiation, embryo development, immunoglobulin V(D)J recombination, in utero embryonic development, lung development, motor neuron axon guidance, negative regulation of transcription, DNA-dependent, pattern specification process, positive regulation of cardiac muscle cell differentiation, positive regulation of epithelial cell proliferation, positive regulation of epithelial cell proliferation involved in lung morphogenesis, positive regulation of immunoglobulin production, positive regulation of mesenchymal cell proliferation, positive regulation of transcription from RNA polymerase II promoter, pre-B cell differentiation, regulation of cardiac muscle cell proliferation, regulation of sequence-specific DNA binding transcription factor activity, sarcomere organization, skeletal muscle tissue development, smooth muscle tissue development, ventral spinal cord development cytoplasm, nucleolus, nucleus, transcription factor complex DNA binding, DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, chromatin binding, double-stranded DNA binding, metal ion binding, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding NOT Human FOXP2 InterPro UniProtKB {GO:0007389=GO_REF:0000033, GO:0021987=PMID:18987363, GO:0003700=GO_REF:0000002, GO:0003705=GO_REF:0000033, GO:0009790=GO_REF:0000033, GO:0009791=GO_REF:0000033, GO:0042803=PMID:16407075, GO:0046872=GO_REF:0000037, GO:0051090=GO_REF:0000033, GO:0005737=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0048745=GO_REF:0000033, GO:0060501=GO_REF:0000033, GO:0043010=GO_REF:0000033, GO:0005667=GO_REF:0000033, GO:0046982=GO_REF:0000033, GO:0048286=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0002053=GO_REF:0000033, GO:0021549=GO_REF:0000033, GO:0003677=PMID:16407075, GO:0043565=GO_REF:0000002, GO:0007519=GO_REF:0000033, GO:0003682=GO_REF:0000033, GO:0042297=GO_REF:0000033, GO:0045892=PMID:18987363, GO:0040007=GO_REF:0000033, GO:0021757=PMID:11872605, GO:0060013=GO_REF:0000033, GO:0021758=PMID:11872605, GO:0008134=GO_REF:0000033} Q0PRL4 Forkhead box P2 variant 3 protein 20130413 {GO:0007389=IBA, GO:0021987=IEP, GO:0003700=IEA, GO:0003705=IBA, GO:0009790=IBA, GO:0009791=IBA, GO:0042803=IDA, GO:0046872=IEA, GO:0051090=IBA, GO:0005737=IBA, GO:0003690=IBA, GO:0048745=IBA, GO:0060501=IBA, GO:0043010=IBA, GO:0005667=IBA, GO:0046982=IBA, GO:0048286=IBA, GO:0008301=IBA, GO:0002053=IBA, GO:0021549=IBA, GO:0003677=IDA, GO:0043565=IEA, GO:0007519=IBA, GO:0003682=IBA, GO:0042297=IBA, GO:0045892=IDA, GO:0040007=IBA, GO:0021757=IMP, GO:0060013=IBA, GO:0021758=IMP, GO:0008134=IBA} camera-type eye development, caudate nucleus development, cerebellum development, cerebral cortex development, embryo development, growth, lung alveolus development, negative regulation of transcription, DNA-dependent, pattern specification process, positive regulation of epithelial cell proliferation involved in lung morphogenesis, positive regulation of mesenchymal cell proliferation, post-embryonic development, putamen development, regulation of sequence-specific DNA binding transcription factor activity, righting reflex, skeletal muscle tissue development, smooth muscle tissue development, vocal learning cytoplasm, transcription factor complex DNA binding, DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, chromatin binding, double-stranded DNA binding, metal ion binding, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human InterPro:IPR001766|InterPro:IPR018122 FOXP3 BHF-UCL UniProtKB {GO:0005515=PMID:20676092, GO:0048302=GO_REF:0000033, GO:0007389=GO_REF:0000033, GO:0032753=GO_REF:0000019, GO:0003700=PMID:11483607, GO:0032693=PMID:15466453, GO:0032715=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0002513=GO_REF:0000033, GO:0032714=GO_REF:0000033, GO:0032713=PMID:15466453, GO:0032792=PMID:16652169, GO:0009790=GO_REF:0000033, GO:0048294=GO_REF:0000033, GO:0009791=GO_REF:0000033, GO:0001816=GO_REF:0000019, GO:0042803=PMID:16920951, GO:0042130=PMID:15466453, GO:0032914=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0045077=GO_REF:0000033, GO:0048745=GO_REF:0000033, GO:0060501=GO_REF:0000033, GO:0002361=GO_REF:0000019, GO:0043029=PMID:11483607, GO:0002262=GO_REF:0000033, GO:0032689=PMID:15466453, GO:0035035=PMID:17360565, GO:0046982=GO_REF:0000033, GO:0048286=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0003714=GO_REF:0000033, GO:0032720=GO_REF:0000033, GO:0002725=PMID:15466453, GO:0021549=GO_REF:0000033, GO:0045085=PMID:16873067, GO:0043234=PMID:16903909, GO:0042110=PMID:15466453, GO:0050777=PMID:15652505, GO:0007519=GO_REF:0000033, GO:0002669=GO_REF:0000033, GO:0008270=GO_REF:0000002, GO:0045893=PMID:19276356, GO:0042297=GO_REF:0000033, GO:0045892=PMID:17360565, GO:0040007=GO_REF:0000033, GO:0002456=GO_REF:0000019, GO:0050852=GO_REF:0000033, GO:0032831=GO_REF:0000033, GO:0001782=GO_REF:0000033, GO:0021987=GO_REF:0000033, GO:0008285=PMID:15652505, GO:0042826=PMID:17360565, GO:0051525=PMID:16873067, GO:0046007=PMID:11483607, GO:0005634=PMID:11483607, GO:0050710=PMID:11483607, GO:0035067=GO_REF:0000033, GO:0035066=PMID:19276356, GO:0043433=PMID:16873067, GO:0005737=GO_REF:0000033, GO:0045944=PMID:19276356, GO:0002677=GO_REF:0000033, GO:0006338=PMID:16903909, GO:0043010=GO_REF:0000033, GO:0032703=PMID:17360565, GO:0005667=GO_REF:0000033, GO:0006355=PMID:11138001, GO:0051059=PMID:16652169, GO:0002851=GO_REF:0000033, GO:0002053=GO_REF:0000033, GO:0032088=PMID:16652169, GO:0009615=PMID:20583921, GO:0033092=GO_REF:0000033, GO:0042036=PMID:11483607, GO:0043565=PMID:19276356, GO:0031064=PMID:19276356, GO:0003682=GO_REF:0000033, GO:0021757=GO_REF:0000033, GO:0060013=GO_REF:0000033, GO:0021758=GO_REF:0000033} Q9BZS1 Forkhead box protein P3 protein 20090803 {GO:0005515=IPI, GO:0048302=IBA, GO:0007389=IBA, GO:0032753=IEA, GO:0003700=IDA, GO:0032693=IDA, GO:0032715=IBA, GO:0003705=IBA, GO:0002513=IBA, GO:0032714=IBA, GO:0032713=IDA, GO:0032792=IDA, GO:0009790=IBA, GO:0048294=IBA, GO:0009791=IBA, GO:0001816=IEA, GO:0042803=IPI, GO:0042130=IDA, GO:0032914=IBA, GO:0003690=IBA, GO:0045077=IBA, GO:0048745=IRD, GO:0060501=IRD, GO:0002361=IEA, GO:0043029=NAS, GO:0002262=IBA, GO:0032689=IDA, GO:0035035=IPI, GO:0046982=IBA, GO:0048286=IRD, GO:0008301=IBA, GO:0003714=IBA, GO:0032720=IBA, GO:0002725=IDA, GO:0021549=IBA, GO:0045085=IMP, GO:0043234=NAS, GO:0042110=IDA, GO:0050777=IDA, GO:0007519=IRD, GO:0002669=IBA, GO:0008270=IEA, GO:0045893=IMP, GO:0042297=IRD, GO:0045892=IDA, GO:0040007=IRD, GO:0002456=IEA, GO:0050852=IBA, GO:0032831=IBA, GO:0001782=IBA, GO:0021987=IRD, GO:0008285=IDA, GO:0042826=IPI, GO:0051525=IPI, GO:0046007=NAS, GO:0005634=IDA, GO:0050710=IDA, GO:0035067=IBA, GO:0035066=IMP, GO:0043433=IDA, GO:0005737=IBA, GO:0045944=IMP, GO:0002677=IBA, GO:0006338=NAS, GO:0043010=IRD, GO:0032703=IDA, GO:0005667=IBA, GO:0006355=NAS, GO:0051059=NAS, GO:0002851=IBA, GO:0002053=IRD, GO:0032088=IDA, GO:0009615=IEP, GO:0033092=IBA, GO:0042036=IDA, GO:0043565=IDA, GO:0031064=IGI, GO:0003682=IBA, GO:0021757=IRD, GO:0060013=IRD, GO:0021758=IRD} B cell homeostasis, CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation, T cell activation, T cell homeostasis, T cell mediated immunity, T cell receptor signaling pathway, camera-type eye development, caudate nucleus development, cerebellum development, cerebral cortex development, chromatin remodeling, cytokine production, embryo development, growth, lung alveolus development, myeloid cell homeostasis, negative regulation of CREB transcription factor activity, negative regulation of NF-kappaB transcription factor activity, negative regulation of T cell cytokine production, negative regulation of T cell proliferation, negative regulation of activated T cell proliferation, negative regulation of cell proliferation, negative regulation of chronic inflammatory response, negative regulation of cytokine biosynthetic process, negative regulation of cytokine secretion, negative regulation of histone acetylation, negative regulation of histone deacetylation, negative regulation of immune response, negative regulation of interferon-gamma biosynthetic process, negative regulation of interferon-gamma production, negative regulation of interleukin-10 production, negative regulation of interleukin-2 biosynthetic process, negative regulation of interleukin-2 production, negative regulation of interleukin-4 production, negative regulation of interleukin-5 production, negative regulation of interleukin-6 production, negative regulation of isotype switching to IgE isotypes, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription, DNA-dependent, negative regulation of tumor necrosis factor production, pattern specification process, positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation, positive regulation of T cell anergy, positive regulation of epithelial cell proliferation involved in lung morphogenesis, positive regulation of histone acetylation, positive regulation of immature T cell proliferation in thymus, positive regulation of interleukin-4 production, positive regulation of mesenchymal cell proliferation, positive regulation of peripheral T cell tolerance induction, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of transforming growth factor beta1 production, post-embryonic development, putamen development, regulation of isotype switching to IgG isotypes, regulation of transcription, DNA-dependent, response to virus, righting reflex, skeletal muscle tissue development, smooth muscle tissue development, tolerance induction to self antigen, vocal learning cytoplasm, nucleus, protein complex, transcription factor complex DNA binding, bending, NF-kappaB binding, NFAT protein binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, chromatin binding, double-stranded DNA binding, histone acetyltransferase binding, histone deacetylase binding, protein binding, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity, zinc ion binding Human UniProtKB:P56524 FOXP4 RefGenome UniProtKB {GO:0005667=GO_REF:0000033, GO:0007389=GO_REF:0000033, GO:0003700=GO_REF:0000002, GO:0046982=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0042803=GO_REF:0000033, GO:0046872=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0007507=GO_REF:0000033, GO:0051090=GO_REF:0000033, GO:0005737=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0003682=GO_REF:0000033, GO:0048617=GO_REF:0000033, GO:0009888=GO_REF:0000033, GO:0008134=GO_REF:0000033} Q8IVH2 Forkhead box protein P4 protein 20100514 {GO:0005667=IBA, GO:0007389=IBA, GO:0003700=IEA, GO:0046982=IBA, GO:0008301=IBA, GO:0003705=IBA, GO:0042803=IBA, GO:0046872=IEA, GO:0043565=IEA, GO:0007507=IBA, GO:0051090=IBA, GO:0005737=IBA, GO:0003690=IBA, GO:0003682=IBA, GO:0048617=IBA, GO:0009888=IBA, GO:0008134=IBA} embryonic foregut morphogenesis, heart development, pattern specification process, regulation of sequence-specific DNA binding transcription factor activity, tissue development cytoplasm, transcription factor complex DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, chromatin binding, double-stranded DNA binding, metal ion binding, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human PANTHER:PTN000215024 FOXQ1 RefGenome UniProtKB {GO:0005667=GO_REF:0000033, GO:0007389=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0030331=GO_REF:0000033, GO:0009790=GO_REF:0000033, GO:0031069=GO_REF:0000033, GO:0043280=GO_REF:0000033, GO:0043565=GO_REF:0000002, GO:0051090=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0006309=GO_REF:0000033, GO:0045944=GO_REF:0000033, GO:0031624=GO_REF:0000033, GO:0043028=GO_REF:0000033, GO:0008134=GO_REF:0000033} Q9C009 Forkhead box protein Q1 protein 20100514 {GO:0005667=IBA, GO:0007389=IBA, GO:0008301=IBA, GO:0003705=IBA, GO:0030331=IBA, GO:0009790=IBA, GO:0031069=IBA, GO:0043280=IBA, GO:0043565=IEA, GO:0051090=IBA, GO:0003690=IBA, GO:0006309=IBA, GO:0045944=IBA, GO:0031624=IBA, GO:0043028=IBA, GO:0008134=IBA} apoptotic DNA fragmentation, embryo development, hair follicle morphogenesis, pattern specification process, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of transcription from RNA polymerase II promoter, regulation of sequence-specific DNA binding transcription factor activity transcription factor complex DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, cysteine-type endopeptidase regulator activity involved in apoptotic process, double-stranded DNA binding, estrogen receptor binding, sequence-specific DNA binding, transcription factor binding, ubiquitin conjugating enzyme binding Human PANTHER:PTN000215024 FOXRED1 LIFEdb UniProtKB {GO:0005739=GO_REF:0000054, GO:0008150=GO_REF:0000015, GO:0016491=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q96CU9 FAD-dependent oxidoreductase domain-containing protein 1 protein 20100607 {GO:0005739=IDA, GO:0008150=ND, GO:0016491=IEA, GO:0016021=IEA} biological_process integral to membrane, mitochondrion oxidoreductase activity Human FOXRED2 UniProtKB UniProtKB {GO:0005515=PMID:19706418, GO:0050660=PMID:19706418, GO:0016491=GO_REF:0000037, GO:0005788=PMID:19706418, GO:0030433=PMID:19706418} Q8IWF2 FAD-dependent oxidoreductase domain-containing protein 2 protein 20110128 {GO:0005515=IPI, GO:0050660=IDA, GO:0016491=IEA, GO:0005788=IDA, GO:0030433=IMP} ER-associated protein catabolic process endoplasmic reticulum lumen flavin adenine dinucleotide binding, oxidoreductase activity, protein binding Human UniProtKB:Q13438-2 FOXS1 UniProtKB UniProtKB {GO:0001656=GO_REF:0000033, GO:0008286=GO_REF:0000033, GO:0001657=GO_REF:0000033, GO:0003700=PMID:9325056, GO:0055010=GO_REF:0000033, GO:0003705=GO_REF:0000033, GO:0001756=GO_REF:0000033, GO:0005634=GO_REF:0000024, GO:0048844=GO_REF:0000033, GO:0048703=GO_REF:0000033, GO:0043433=GO_REF:0000024, GO:0001946=GO_REF:0000033, GO:0014034=GO_REF:0000033, GO:0050880=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0007219=GO_REF:0000033, GO:0030199=GO_REF:0000033, GO:0045944=GO_REF:0000033, GO:0050885=GO_REF:0000033, GO:0043010=GO_REF:0000033, GO:0040018=GO_REF:0000033, GO:0048010=GO_REF:0000033, GO:0005667=GO_REF:0000033, GO:0046620=GO_REF:0000033, GO:0006355=GO_REF:0000029, GO:0001569=GO_REF:0000033, GO:0001568=GO_REF:0000024, GO:0035050=GO_REF:0000033, GO:0008301=GO_REF:0000033, GO:0007275=GO_REF:0000029, GO:0003677=GO_REF:0000024, GO:0060038=GO_REF:0000033, GO:0031490=GO_REF:0000033, GO:0043565=GO_REF:0000002, GO:0001503=GO_REF:0000033, GO:0001974=GO_REF:0000033, GO:0048343=GO_REF:0000033, GO:0045892=GO_REF:0000024, GO:0001570=GO_REF:0000033, GO:0008134=GO_REF:0000033} O43638 Forkhead box protein S1 protein 20091127 {GO:0001656=IRD, GO:0008286=IBA, GO:0001657=IRD, GO:0003700=TAS, GO:0055010=IBA, GO:0003705=IBA, GO:0001756=IBA, GO:0005634=ISS, GO:0048844=IBA, GO:0048703=IRD, GO:0043433=ISS, GO:0001946=IBA, GO:0014034=IBA, GO:0050880=IBA, GO:0003690=IBA, GO:0007219=IBA, GO:0030199=IBA, GO:0045944=IBA, GO:0050885=IBA, GO:0043010=IBA, GO:0040018=IBA, GO:0048010=IBA, GO:0005667=IBA, GO:0046620=IBA, GO:0006355=NAS, GO:0001569=IBA, GO:0001568=ISS, GO:0035050=IBA, GO:0008301=IBA, GO:0007275=NAS, GO:0003677=ISS, GO:0060038=IBA, GO:0031490=IBA, GO:0043565=IEA, GO:0001503=IBA, GO:0001974=IBA, GO:0048343=IBA, GO:0045892=ISS, GO:0001570=IBA, GO:0008134=IBA} Notch signaling pathway, artery morphogenesis, blood vessel development, blood vessel remodeling, camera-type eye development, cardiac muscle cell proliferation, collagen fibril organization, embryonic heart tube development, embryonic viscerocranium morphogenesis, insulin receptor signaling pathway, lymphangiogenesis, metanephros development, multicellular organismal development, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription, DNA-dependent, neural crest cell fate commitment, neuromuscular process controlling balance, ossification, paraxial mesodermal cell fate commitment, patterning of blood vessels, positive regulation of multicellular organism growth, positive regulation of transcription from RNA polymerase II promoter, regulation of blood vessel size, regulation of organ growth, regulation of transcription, DNA-dependent, somitogenesis, ureteric bud development, vascular endothelial growth factor receptor signaling pathway, vasculogenesis, ventricular cardiac muscle tissue morphogenesis nucleus, transcription factor complex DNA binding, DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, chromatin DNA binding, double-stranded DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human UniProtKB:Q61574 FPGS InterPro UniProtKB {GO:0031100=GO_REF:0000019, GO:0005743=GO_REF:0000039, GO:0006767=Reactome:REACT_11238, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000002, GO:0042221=GO_REF:0000019, GO:0004326=GO_REF:0000002, GO:0005829=Reactome:REACT_11098, GO:0001889=GO_REF:0000019, GO:0005739=PMID:7721888, GO:0005737=PMID:1409616, GO:0006139=PMID:7721888, GO:0006766=Reactome:REACT_11193, GO:0007420=GO_REF:0000019, GO:0005759=Reactome:REACT_11134, GO:0046655=Reactome:REACT_11167, GO:0006730=GO_REF:0000037} Q5JU23 Folylpolyglutamate synthase, mitochondrial protein 20130413 {GO:0031100=IEA, GO:0005743=IEA, GO:0006767=TAS, GO:0044281=TAS, GO:0005524=IEA, GO:0042221=IEA, GO:0004326=IEA, GO:0005829=TAS, GO:0001889=IEA, GO:0005739=TAS, GO:0005737=TAS, GO:0006139=TAS, GO:0006766=TAS, GO:0007420=IEA, GO:0005759=TAS, GO:0046655=TAS, GO:0006730=IEA} brain development, folic acid metabolic process, liver development, nucleobase-containing compound metabolic process, one-carbon metabolic process, organ regeneration, response to chemical stimulus, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cytoplasm, cytosol, mitochondrial inner membrane, mitochondrial matrix, mitochondrion ATP binding, tetrahydrofolylpolyglutamate synthase activity Human InterPro:IPR001645|InterPro:IPR013221|InterPro:IPR018109 FPGT PINC UniProtKB {GO:0005737=GO_REF:0000039, GO:0047341=GO_REF:0000003, GO:0016779=GO_REF:0000038, GO:0006004=PMID:9804772, GO:0003824=PMID:9804772, GO:0005525=GO_REF:0000037, GO:0016772=GO_REF:0000002} O14772 Fucose-1-phosphate guanylyltransferase protein 20030904 {GO:0005737=IEA, GO:0047341=IEA, GO:0016779=IEA, GO:0006004=TAS, GO:0003824=TAS, GO:0005525=IEA, GO:0016772=IEA} fucose metabolic process cytoplasm GTP binding, catalytic activity, fucose-1-phosphate guanylyltransferase activity, nucleotidyltransferase activity, transferase activity, transferring phosphorus-containing groups Human FPR1 IntAct UniProtKB {GO:0005515=PMID:22447027, GO:0042554=GO_REF:0000002, GO:0007263=PMID:10861041, GO:0005886=Reactome:REACT_22289, GO:0006928=PMID:10882119, GO:0004982=PMID:12218158, GO:0000187=PMID:10857861, GO:0007165=PMID:10820279, GO:0006935=GO_REF:0000037, GO:0007186=PMID:10823817, GO:0007188=PMID:10889468, GO:0004872=PMID:10857861, GO:0016021=GO_REF:0000037, GO:0005768=PMID:10823817} P21462 fMet-Leu-Phe receptor protein 20130415 {GO:0005515=IPI, GO:0042554=IEA, GO:0007263=TAS, GO:0005886=TAS, GO:0006928=TAS, GO:0004982=IDA, GO:0000187=TAS, GO:0007165=TAS, GO:0006935=IEA, GO:0007186=TAS, GO:0007188=TAS, GO:0004872=TAS, GO:0016021=IEA, GO:0005768=TAS} G-protein coupled receptor signaling pathway, activation of MAPK activity, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, cellular component movement, chemotaxis, nitric oxide mediated signal transduction, signal transduction, superoxide anion generation endosome, integral to membrane, plasma membrane N-formyl peptide receptor activity, protein binding, receptor activity Human UniProtKB:P25098 FPR2 Reactome UniProtKB {GO:0042554=GO_REF:0000002, GO:0004982=GO_REF:0000002, GO:0006954=GO_REF:0000002, GO:0005886=Reactome:REACT_22436, GO:0007186=PMID:9054386, GO:0006935=GO_REF:0000037, GO:0004930=PMID:9054386, GO:0006928=PMID:1374236, GO:0016021=GO_REF:0000037, GO:0007155=PMID:9054386} P25090 N-formyl peptide receptor 2 protein 20091023 {GO:0042554=IEA, GO:0004982=IEA, GO:0006954=IEA, GO:0005886=TAS, GO:0007186=TAS, GO:0006935=IEA, GO:0004930=TAS, GO:0006928=TAS, GO:0016021=IEA, GO:0007155=TAS} G-protein coupled receptor signaling pathway, cell adhesion, cellular component movement, chemotaxis, inflammatory response, superoxide anion generation integral to membrane, plasma membrane G-protein coupled receptor activity, N-formyl peptide receptor activity Human FRA10AC1 IntAct UniProtKB {GO:0005515=PMID:16169070, GO:0005634=GO_REF:0000039} Q70Z53 Protein FRA10AC1 protein 20130415 {GO:0005515=IPI, GO:0005634=IEA} nucleus protein binding Human UniProtKB:Q12852 FRAS1 BHF-UCL UniProtKB {GO:0031012=PMID:22261194, GO:0007154=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q86XX4 Extracellular matrix protein FRAS1 protein 20120228 {GO:0031012=ISS, GO:0007154=IEA, GO:0005886=IEA, GO:0016021=IEA, GO:0046872=IEA} cell communication extracellular matrix, integral to membrane, plasma membrane metal ion binding colocalizes_with Human UniProtKB:F1RYS0 FRAT1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0016055=GO_REF:0000037} Q92837 Proto-oncogene FRAT1 protein 20130413 {GO:0005737=IEA, GO:0016055=IEA} Wnt receptor signaling pathway cytoplasm Human UniProtKB-SubCell:SL-0086 FRAT2 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008283=PMID:9635432, GO:0007275=PMID:9635432, GO:0005575=GO_REF:0000015, GO:0016055=GO_REF:0000037} O75474 GSK-3-binding protein FRAT2 protein 20061026 {GO:0003674=ND, GO:0008283=NAS, GO:0007275=NAS, GO:0005575=ND, GO:0016055=IEA} Wnt receptor signaling pathway, cell proliferation, multicellular organismal development cellular_component molecular_function Human FREM1 UniProtKB UniProtKB {GO:0007154=GO_REF:0000002, GO:0007160=GO_REF:0000019, GO:0030246=GO_REF:0000002, GO:0016021=GO_REF:0000002, GO:0097094=PMID:21931569, GO:0046872=GO_REF:0000037, GO:0005604=GO_REF:0000039} Q5H8C1 FRAS1-related extracellular matrix protein 1 protein 20120426 {GO:0007154=IEA, GO:0007160=IEA, GO:0030246=IEA, GO:0016021=IEA, GO:0097094=IMP, GO:0046872=IEA, GO:0005604=IEA} cell communication, cell-matrix adhesion, craniofacial suture morphogenesis basement membrane, integral to membrane carbohydrate binding, metal ion binding Human FREM2 UniProtKB UniProtKB {GO:0048839=GO_REF:0000019, GO:0007154=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0002009=GO_REF:0000019, GO:0007156=GO_REF:0000002, GO:0005604=GO_REF:0000019} Q5SZK8 FRAS1-related extracellular matrix protein 2 protein 20130413 {GO:0048839=IEA, GO:0007154=IEA, GO:0005886=IEA, GO:0005509=IEA, GO:0016021=IEA, GO:0002009=IEA, GO:0007156=IEA, GO:0005604=IEA} cell communication, homophilic cell adhesion, inner ear development, morphogenesis of an epithelium basement membrane, integral to membrane, plasma membrane calcium ion binding Human UniProtKB-SubCell:SL-0039 FRG1 UniProtKB UniProtKB {GO:0015030=GO_REF:0000039, GO:0016607=GO_REF:0000039, GO:0000398=PMID:11991638, GO:0006364=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0071013=PMID:11991638} Q14331 Protein FRG1 protein 20110302 {GO:0015030=IEA, GO:0016607=IEA, GO:0000398=IC, GO:0006364=IEA, GO:0005730=IEA, GO:0071013=IDA} mRNA splicing, via spliceosome, rRNA processing Cajal body, catalytic step 2 spliceosome, nuclear speck, nucleolus Human FRK IntAct UniProtKB {GO:0005622=PMID:7510261, GO:0005515=PMID:19345329, GO:0005737=GO_REF:0000039, GO:0008285=PMID:7664264, GO:0005886=GO_REF:0000019, GO:0006468=PMID:7696183, GO:0005634=GO_REF:0000039, GO:0004713=GO_REF:0000038, GO:0004715=GO_REF:0000003, GO:0005524=GO_REF:0000037, GO:0030154=GO_REF:0000019} P42685 Tyrosine-protein kinase FRK protein 20130415 {GO:0005622=TAS, GO:0005515=IPI, GO:0005737=IEA, GO:0008285=TAS, GO:0005886=IEA, GO:0006468=TAS, GO:0005634=IEA, GO:0004713=IEA, GO:0004715=IEA, GO:0005524=IEA, GO:0030154=IEA} cell differentiation, negative regulation of cell proliferation, protein phosphorylation cytoplasm, intracellular, nucleus, plasma membrane ATP binding, non-membrane spanning protein tyrosine kinase activity, protein binding, protein tyrosine kinase activity Human UniProtKB:P60484 FRMD4A UniProtKB UniProtKB {GO:0090162=GO_REF:0000019, GO:0005737=GO_REF:0000037, GO:0005923=GO_REF:0000019, GO:0030674=GO_REF:0000019, GO:0005856=GO_REF:0000039} Q9P2Q2 FERM domain-containing protein 4A protein 20130413 {GO:0090162=IEA, GO:0005737=IEA, GO:0005923=IEA, GO:0030674=IEA, GO:0005856=IEA} establishment of epithelial cell polarity cytoplasm, cytoskeleton, tight junction protein binding, bridging Human UniProtKB-SubCell:SL-0090 FRMD4B UniProtKB UniProtKB {GO:0090162=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0005856=GO_REF:0000039, GO:0001726=GO_REF:0000019} Q9Y2L6 FERM domain-containing protein 4B protein 20130413 {GO:0090162=IEA, GO:0005737=IEA, GO:0005856=IEA, GO:0001726=IEA} establishment of epithelial cell polarity cytoplasm, cytoskeleton, ruffle Human UniProtKB-SubCell:SL-0090 FRMD5 BHF-UCL UniProtKB {GO:0008092=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037, GO:0005856=GO_REF:0000002, GO:0019898=GO_REF:0000002} Q7Z6J6 FERM domain-containing protein 5 protein 20110712 {GO:0008092=IEA, GO:0003674=ND, GO:0008150=ND, GO:0005737=IEA, GO:0005575=ND, GO:0016021=IEA, GO:0005856=IEA, GO:0019898=IEA} biological_process cellular_component, cytoplasm, cytoskeleton, extrinsic to membrane, integral to membrane cytoskeletal protein binding, molecular_function Human FRMD6 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0043296=GO_REF:0000019, GO:0003383=GO_REF:0000019, GO:0032970=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0034613=GO_REF:0000019, GO:0005856=GO_REF:0000002} Q96NE9 FERM domain-containing protein 6 protein 20080205 {GO:0005739=IDA, GO:0043296=IEA, GO:0003383=IEA, GO:0032970=IEA, GO:0005886=IEA, GO:0034613=IEA, GO:0005856=IEA} apical constriction, cellular protein localization, regulation of actin filament-based process apical junction complex, cytoskeleton, mitochondrion, plasma membrane Human FRMD8 InterPro UniProtKB {GO:0005856=GO_REF:0000002} Q9BZ67 FERM domain-containing protein 8 protein 20130413 {GO:0005856=IEA} cytoskeleton Human InterPro:IPR000299 FRMPD1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000039, GO:0005856=GO_REF:0000002, GO:0005829=GO_REF:0000039} Q5SYB0 FERM and PDZ domain-containing protein 1 protein 20120912 {GO:0005737=IDA, GO:0005886=IEA, GO:0005856=IEA, GO:0005829=IEA} cytoplasm, cytoskeleton, cytosol, plasma membrane Human FRMPD4 UniProtKB UniProtKB {GO:0005515=PMID:19118189, GO:0043197=PMID:19118189, GO:0051835=PMID:19118189, GO:0005546=PMID:19118189, GO:0005856=GO_REF:0000002} Q14CM0 FERM and PDZ domain-containing protein 4 protein 20091109 {GO:0005515=IPI, GO:0043197=IDA, GO:0051835=IMP, GO:0005546=IDA, GO:0005856=IEA} positive regulation of synapse structural plasticity cytoskeleton, dendritic spine phosphatidylinositol-4,5-bisphosphate binding, protein binding Human UniProtKB:P78352 FRS2 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005515=PMID:9660748, GO:0005886=Reactome:REACT_147854, GO:0005158=GO_REF:0000002, GO:0046619=GO_REF:0000019, GO:0003281=GO_REF:0000019, GO:0001759=GO_REF:0000019, GO:0007405=GO_REF:0000019, GO:0000187=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0000186=Reactome:REACT_12005, GO:0007173=Reactome:REACT_9417, GO:0005068=PMID:9660748, GO:0008595=GO_REF:0000019, GO:0060527=GO_REF:0000019, GO:0050678=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0005168=PMID:15488758, GO:0048015=Reactome:REACT_12464, GO:0019211=PMID:9660748, GO:0005104=PMID:9660748, GO:0001702=GO_REF:0000019, GO:0012505=GO_REF:0000039, GO:0007186=PMID:9660748, GO:0016020=PMID:9660748, GO:0008543=Reactome:REACT_9470, GO:0005887=PMID:9660748, GO:0045087=Reactome:REACT_6802, GO:0007185=PMID:9660748, GO:0030900=GO_REF:0000019, GO:0005768=Reactome:REACT_12063} Q8WU20 Fibroblast growth factor receptor substrate 2 protein 20070120 {GO:0008286=TAS, GO:0005515=IPI, GO:0005886=TAS, GO:0005158=IEA, GO:0046619=IEA, GO:0003281=IEA, GO:0001759=IEA, GO:0007405=IEA, GO:0000187=IEA, GO:0005737=IEA, GO:0000186=TAS, GO:0007173=TAS, GO:0005068=TAS, GO:0008595=IEA, GO:0060527=IEA, GO:0050678=IEA, GO:0048011=TAS, GO:0005168=IPI, GO:0048015=TAS, GO:0019211=TAS, GO:0005104=IPI, GO:0001702=IEA, GO:0012505=IEA, GO:0007186=TAS, GO:0016020=TAS, GO:0008543=TAS, GO:0005887=TAS, GO:0045087=TAS, GO:0007185=TAS, GO:0030900=IEA, GO:0005768=TAS} G-protein coupled receptor signaling pathway, activation of MAPK activity, activation of MAPKK activity, anterior/posterior axis specification, embryo, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, forebrain development, gastrulation with mouth forming second, innate immune response, insulin receptor signaling pathway, neuroblast proliferation, neurotrophin TRK receptor signaling pathway, optic placode formation involved in camera-type eye formation, organ induction, phosphatidylinositol-mediated signaling, prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis, regulation of epithelial cell proliferation, transmembrane receptor protein tyrosine phosphatase signaling pathway, ventricular septum development cytoplasm, endomembrane system, endosome, integral to plasma membrane, membrane, plasma membrane fibroblast growth factor receptor binding, insulin receptor binding, neurotrophin TRKA receptor binding, phosphatase activator activity, protein binding, transmembrane receptor protein tyrosine kinase adaptor activity Human FRS3 Reactome UniProtKB {GO:0007165=PMID:8761293, GO:0005886=Reactome:REACT_111238, GO:0008543=Reactome:REACT_9470, GO:0005158=GO_REF:0000002, GO:0005104=PMID:9660748} O43559 Fibroblast growth factor receptor substrate 3 protein 20100226 {GO:0007165=TAS, GO:0005886=TAS, GO:0008543=TAS, GO:0005158=IEA, GO:0005104=IPI} fibroblast growth factor receptor signaling pathway, signal transduction plasma membrane fibroblast growth factor receptor binding, insulin receptor binding Human FRY UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0000922=GO_REF:0000039, GO:0005815=GO_REF:0000039} Q5TBA9 Protein furry homolog protein 20130413 {GO:0005737=IEA, GO:0000922=IEA, GO:0005815=IEA} cytoplasm, microtubule organizing center, spindle pole Human UniProtKB-SubCell:SL-0048 FRYL UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0006351=GO_REF:0000037} O94915 Protein furry homolog-like protein 20130413 {GO:0006355=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent Human UniProtKB-KW:KW-0805 FRZB BHF-UCL UniProtKB {GO:0008406=GO_REF:0000033, GO:0017147=GO_REF:0000024, GO:0060429=GO_REF:0000033, GO:0030308=PMID:20208569, GO:0008285=PMID:20208569, GO:0030178=PMID:20208569, GO:0007409=GO_REF:0000033, GO:0005615=PMID:22261194, GO:0060029=GO_REF:0000019, GO:0005737=GO_REF:0000033, GO:0014033=GO_REF:0000019, GO:0090103=GO_REF:0000033, GO:0016055=GO_REF:0000037, GO:0090090=PMID:17471511, GO:0001944=GO_REF:0000033, GO:0042813=GO_REF:0000033, GO:0010721=GO_REF:0000019, GO:0043065=PMID:18166153, GO:0060056=GO_REF:0000033, GO:0032589=GO_REF:0000033, GO:0030165=GO_REF:0000033, GO:0070367=GO_REF:0000033, GO:0061053=GO_REF:0000019, GO:0001501=PMID:8824257, GO:0016020=PMID:8824257, GO:0007420=GO_REF:0000033, GO:0045600=PMID:12055200, GO:0061037=GO_REF:0000033} Q92765 Secreted frizzled-related protein 3 protein 20120228 {GO:0008406=IBA, GO:0017147=ISS, GO:0060429=IBA, GO:0030308=IDA, GO:0008285=IDA, GO:0030178=IDA, GO:0007409=IRD, GO:0005615=ISS, GO:0060029=IEA, GO:0005737=IBA, GO:0014033=IEA, GO:0090103=IBA, GO:0016055=IEA, GO:0090090=IDA, GO:0001944=IBA, GO:0042813=IBA, GO:0010721=IEA, GO:0043065=IGI, GO:0060056=IBA, GO:0032589=IKR, GO:0030165=IBA, GO:0070367=IBA, GO:0061053=IEA, GO:0001501=TAS, GO:0016020=TAS, GO:0007420=IBA, GO:0045600=IDA, GO:0061037=IBA} Wnt receptor signaling pathway, axonogenesis, brain development, cochlea morphogenesis, convergent extension involved in organogenesis, epithelium development, gonad development, mammary gland involution, negative regulation of Wnt receptor signaling pathway, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cartilage development, negative regulation of cell development, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of hepatocyte differentiation, neural crest cell differentiation, positive regulation of apoptotic process, positive regulation of fat cell differentiation, skeletal system development, somite development, vasculature development cytoplasm, extracellular space, membrane, neuron projection membrane PDZ domain binding, Wnt-activated receptor activity, Wnt-protein binding Human UniProtKB:F1RYL4 FSCN1 IntAct UniProtKB {GO:0005515=PMID:21706053, GO:0001725=PMID:3525578, GO:0030054=GO_REF:0000037, GO:0030036=PMID:9571235, GO:0008283=PMID:8068206, GO:0003779=PMID:20393565, GO:0030175=PMID:3525578, GO:0015629=PMID:3525578, GO:0005829=GO_REF:0000039, GO:0005737=GO_REF:0000038, GO:0051015=PMID:17671164, GO:0016477=PMID:20393565, GO:0008144=PMID:20393565, GO:0048870=PMID:9571235, GO:0071437=PMID:20137952, GO:0030674=GO_REF:0000002, GO:0005856=GO_REF:0000040, GO:0051017=PMID:20393565} Q16658 Fascin protein 20130415 {GO:0005515=IPI, GO:0001725=IDA, GO:0030054=IEA, GO:0030036=IDA, GO:0008283=TAS, GO:0003779=IDA, GO:0030175=IDA, GO:0015629=IDA, GO:0005829=IEA, GO:0005737=IEA, GO:0051015=IDA, GO:0016477=IMP, GO:0008144=IDA, GO:0048870=IDA, GO:0071437=IDA, GO:0030674=IEA, GO:0005856=IEA, GO:0051017=IDA} actin cytoskeleton organization, actin filament bundle assembly, cell migration, cell motility, cell proliferation actin cytoskeleton, cell junction, cytoplasm, cytoskeleton, cytosol, filopodium, invadopodium, stress fiber actin binding, actin filament binding, drug binding, protein binding, protein binding, bridging Human UniProtKB:Q9ULL4 FSCN2 PINC UniProtKB {GO:0005737=GO_REF:0000037, GO:0030036=GO_REF:0000024, GO:0051015=GO_REF:0000024, GO:0032420=GO_REF:0000039, GO:0003779=GO_REF:0000024, GO:0015629=GO_REF:0000024, GO:0030674=GO_REF:0000002, GO:0007601=PMID:10783262, GO:0009653=PMID:10783262, GO:0051017=PMID:10783262, GO:0042462=GO_REF:0000019} O14926 Fascin-2 protein 20030904 {GO:0005737=IEA, GO:0030036=ISS, GO:0051015=ISS, GO:0032420=IEA, GO:0003779=ISS, GO:0015629=ISS, GO:0030674=IEA, GO:0007601=TAS, GO:0009653=TAS, GO:0051017=TAS, GO:0042462=IEA} actin cytoskeleton organization, actin filament bundle assembly, anatomical structure morphogenesis, eye photoreceptor cell development, visual perception actin cytoskeleton, cytoplasm, stereocilium actin binding, actin filament binding, protein binding, bridging Human FSD1 HPA UniProtKB {GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0007067=GO_REF:0000037, GO:0005815=GO_REF:0000039, GO:0005874=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0032154=GO_REF:0000039, GO:0051301=GO_REF:0000037} Q9BTV5 Fibronectin type III and SPRY domain-containing protein 1 protein 20110516 {GO:0005622=IEA, GO:0005737=IDA, GO:0007067=IEA, GO:0005815=IEA, GO:0005874=IEA, GO:0005634=IEA, GO:0032154=IEA, GO:0051301=IEA} cell division, mitosis cleavage furrow, cytoplasm, intracellular, microtubule, microtubule organizing center, nucleus Human FSD1L UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q9BXM9 FSD1-like protein protein 20061026 {GO:0005622=IEA, GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component, intracellular molecular_function Human FSHB BHF-UCL UniProtKB {GO:0005515=PMID:15662415, GO:0008284=PMID:20613903, GO:0007565=PMID:8220432, GO:0030335=PMID:20613903, GO:0006701=PMID:14557487, GO:0046982=GO_REF:0000029, GO:0016913=GO_REF:0000029, GO:0005576=Reactome:REACT_22268, GO:0007283=GO_REF:0000029, GO:0007292=PMID:8220432, GO:0007165=PMID:8220432, GO:0001541=GO_REF:0000029, GO:0005737=PMID:14602737, GO:0005179=PMID:8220432, GO:0016486=Reactome:REACT_15452, GO:0007179=PMID:14557487, GO:0060011=GO_REF:0000019, GO:0044267=Reactome:REACT_17015} P01225 Follitropin subunit beta protein 20120821 {GO:0005515=IPI, GO:0008284=NAS, GO:0007565=TAS, GO:0030335=NAS, GO:0006701=TAS, GO:0046982=NAS, GO:0016913=NAS, GO:0005576=TAS, GO:0007283=NAS, GO:0007292=TAS, GO:0007165=TAS, GO:0001541=NAS, GO:0005737=IDA, GO:0005179=TAS, GO:0016486=TAS, GO:0007179=IEP, GO:0060011=IEA, GO:0044267=TAS} Sertoli cell proliferation, cellular protein metabolic process, female gamete generation, female pregnancy, ovarian follicle development, peptide hormone processing, positive regulation of cell migration, positive regulation of cell proliferation, progesterone biosynthetic process, signal transduction, spermatogenesis, transforming growth factor beta receptor signaling pathway cytoplasm, extracellular region follicle-stimulating hormone activity, hormone activity, protein binding, protein heterodimerization activity Human FSHR GOC UniProtKB {GO:0005515=PMID:15196694, GO:0008406=PMID:9020851, GO:0005886=Reactome:REACT_22268, GO:0009986=GO_REF:0000019, GO:0042699=PMID:9020851, GO:0004963=GO_REF:0000002, GO:0007283=PMID:9020851, GO:0007292=PMID:9020851, GO:0008585=PMID:7553856, GO:0045056=GO_REF:0000019, GO:0007186=PMID:9020851, GO:0016021=GO_REF:0000037, GO:0007189=GO_REF:0000019, GO:0017046=GO_REF:0000019, GO:0035093=GO_REF:0000019, GO:0008584=PMID:17848411, GO:0005768=GO_REF:0000019, GO:0033044=GO_REF:0000019} P23945 Follicle-stimulating hormone receptor protein 20130413 {GO:0005515=IPI, GO:0008406=TAS, GO:0005886=TAS, GO:0009986=IEA, GO:0042699=TAS, GO:0004963=IEA, GO:0007283=TAS, GO:0007292=TAS, GO:0008585=TAS, GO:0045056=IEA, GO:0007186=TAS, GO:0016021=IEA, GO:0007189=IEA, GO:0017046=IEA, GO:0035093=IEA, GO:0008584=IEP, GO:0005768=IEA, GO:0033044=IEA} G-protein coupled receptor signaling pathway, adenylate cyclase-activating G-protein coupled receptor signaling pathway, female gamete generation, female gonad development, follicle-stimulating hormone signaling pathway, gonad development, male gonad development, regulation of chromosome organization, spermatogenesis, spermatogenesis, exchange of chromosomal proteins, transcytosis cell surface, endosome, integral to membrane, plasma membrane follicle-stimulating hormone receptor activity, peptide hormone binding, protein binding Human FSIP1 null null {} null null null null {} null null null FSIP2 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0030529=GO_REF:0000038, GO:0003676=GO_REF:0000038} Q8NAU3 Fibrous sheath-interacting protein 2 protein 20130413 {GO:0005739=IEA, GO:0030529=IEA, GO:0003676=IEA} mitochondrion, ribonucleoprotein complex nucleic acid binding Human UniProtKB-KW:KW-0687 FST Reactome UniProtKB {GO:0005515=PMID:16198295, GO:0007389=GO_REF:0000019, GO:0007276=GO_REF:0000019, GO:0046882=GO_REF:0000029, GO:0032926=PMID:11948405, GO:0005576=Reactome:REACT_150395, GO:0005634=GO_REF:0000019, GO:0043395=GO_REF:0000019, GO:0000122=PMID:12702211, GO:0030509=GO_REF:0000019, GO:0043616=GO_REF:0000019, GO:0031069=GO_REF:0000019, GO:0008585=GO_REF:0000019, GO:0051798=PMID:12514121, GO:0005737=GO_REF:0000019, GO:0002244=PMID:15451575, GO:0048185=PMID:12697670, GO:0042475=GO_REF:0000019, GO:0045596=GO_REF:0000019, GO:0004871=PMID:12702211} P19883 Follistatin protein 20120921 {GO:0005515=IPI, GO:0007389=IEA, GO:0007276=IEA, GO:0046882=NAS, GO:0032926=IDA, GO:0005576=TAS, GO:0005634=IEA, GO:0043395=IEA, GO:0000122=IDA, GO:0030509=IEA, GO:0043616=IEA, GO:0031069=IEA, GO:0008585=IEA, GO:0051798=IDA, GO:0005737=IEA, GO:0002244=IDA, GO:0048185=IPI, GO:0042475=IEA, GO:0045596=IEA, GO:0004871=NAS} BMP signaling pathway, female gonad development, gamete generation, hair follicle morphogenesis, hematopoietic progenitor cell differentiation, keratinocyte proliferation, negative regulation of activin receptor signaling pathway, negative regulation of cell differentiation, negative regulation of follicle-stimulating hormone secretion, negative regulation of transcription from RNA polymerase II promoter, odontogenesis of dentin-containing tooth, pattern specification process, positive regulation of hair follicle development cytoplasm, extracellular region, nucleus activin binding, heparan sulfate proteoglycan binding, protein binding, signal transducer activity Human FSTL1 Reactome UniProtKB {GO:0005509=GO_REF:0000002, GO:0005576=Reactome:REACT_12026, GO:0030509=Reactome:REACT_12034, GO:0005615=PMID:9786430, GO:0008201=GO_REF:0000037} Q12841 Follistatin-related protein 1 protein 20130301 {GO:0005509=IEA, GO:0005576=TAS, GO:0030509=TAS, GO:0005615=TAS, GO:0008201=IEA} BMP signaling pathway extracellular region, extracellular space calcium ion binding, heparin binding Human FSTL3 IntAct UniProtKB {GO:0005515=PMID:15574124, GO:0030325=GO_REF:0000019, GO:0030324=GO_REF:0000019, GO:0005634=PMID:16150905, GO:0007283=GO_REF:0000019, GO:0005615=PMID:16150905, GO:0030514=PMID:17878677, GO:0002244=PMID:15451575, GO:0048185=PMID:12697670, GO:0045944=PMID:17868029, GO:0090101=PMID:17878677, GO:0030141=GO_REF:0000019, GO:0001968=PMID:16336961, GO:0044306=GO_REF:0000019, GO:0005794=GO_REF:0000019, GO:0022409=PMID:16336961, GO:0006357=PMID:11948405, GO:0001822=GO_REF:0000019, GO:0032926=PMID:12697670, GO:0045671=PMID:15574124, GO:0005576=Reactome:REACT_150306, GO:0006351=GO_REF:0000037, GO:0071248=GO_REF:0000019, GO:0001503=GO_REF:0000037, GO:0008584=GO_REF:0000019} O95633 Follistatin-related protein 3 protein 20130415 {GO:0005515=IPI, GO:0030325=IEA, GO:0030324=IEA, GO:0005634=IDA, GO:0007283=IEA, GO:0005615=IDA, GO:0030514=IDA, GO:0002244=IDA, GO:0048185=IPI, GO:0045944=IDA, GO:0090101=IDA, GO:0030141=IEA, GO:0001968=IPI, GO:0044306=IEA, GO:0005794=IEA, GO:0022409=IDA, GO:0006357=IDA, GO:0001822=IEA, GO:0032926=IDA, GO:0045671=IDA, GO:0005576=TAS, GO:0006351=IEA, GO:0071248=IEA, GO:0001503=IEA, GO:0008584=IEA} adrenal gland development, cellular response to metal ion, hematopoietic progenitor cell differentiation, kidney development, lung development, male gonad development, negative regulation of BMP signaling pathway, negative regulation of activin receptor signaling pathway, negative regulation of osteoclast differentiation, negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway, ossification, positive regulation of cell-cell adhesion, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, spermatogenesis, transcription, DNA-dependent Golgi apparatus, extracellular region, extracellular space, neuron projection terminus, nucleus, secretory granule activin binding, fibronectin binding, protein binding Human UniProtKB:O43184-2 FSTL4 UniProtKB UniProtKB {GO:0005509=GO_REF:0000002, GO:0005576=GO_REF:0000039} Q6MZW2 Follistatin-related protein 4 protein 20130413 {GO:0005509=IEA, GO:0005576=IEA} extracellular region calcium ion binding Human UniProtKB-SubCell:SL-0243 FTCD Reactome UniProtKB {GO:0030412=Reactome:REACT_485, GO:0005794=GO_REF:0000039, GO:0019557=GO_REF:0000041, GO:0005814=GO_REF:0000039, GO:0019556=GO_REF:0000041, GO:0006548=Reactome:REACT_1249, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0030409=GO_REF:0000003, GO:0005829=Reactome:REACT_485, GO:0035999=GO_REF:0000041, GO:0034641=Reactome:REACT_13, GO:0005542=GO_REF:0000037, GO:0005737=PMID:10029623, GO:0006760=PMID:10029623, GO:0007010=GO_REF:0000019, GO:0016740=GO_REF:0000002, GO:0044237=GO_REF:0000002} O95954 Formimidoyltransferase-cyclodeaminase protein 20130213 {GO:0030412=EXP, GO:0005794=IEA, GO:0019557=IEA, GO:0005814=IEA, GO:0019556=IEA, GO:0006548=TAS, GO:0044281=TAS, GO:0003824=IEA, GO:0030409=IEA, GO:0005829=TAS, GO:0035999=IEA, GO:0034641=TAS, GO:0005542=IEA, GO:0005737=TAS, GO:0006760=TAS, GO:0007010=IEA, GO:0016740=IEA, GO:0044237=IEA} cellular metabolic process, cellular nitrogen compound metabolic process, cytoskeleton organization, folic acid-containing compound metabolic process, histidine catabolic process, histidine catabolic process to glutamate and formamide, histidine catabolic process to glutamate and formate, small molecule metabolic process, tetrahydrofolate interconversion Golgi apparatus, centriole, cytoplasm, cytosol catalytic activity, folic acid binding, formimidoyltetrahydrofolate cyclodeaminase activity, glutamate formimidoyltransferase activity, transferase activity Human FTH1 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0008285=GO_REF:0000024, GO:0005506=PMID:3020541, GO:0006892=Reactome:REACT_11235, GO:0048147=PMID:9924025, GO:0006880=PMID:9924025, GO:0055085=Reactome:REACT_15518, GO:0008199=GO_REF:0000002, GO:0005829=Reactome:REACT_115629, GO:0006879=Reactome:REACT_25060, GO:0005739=GO_REF:0000019, GO:0008043=PMID:6589621, GO:0004322=GO_REF:0000003, GO:0006955=GO_REF:0000024, GO:0016491=GO_REF:0000002, GO:0006826=GO_REF:0000002, GO:0016044=Reactome:REACT_11123} P02794 Ferritin heavy chain protein 20130415 {GO:0005515=IPI, GO:0008285=ISS, GO:0005506=TAS, GO:0006892=TAS, GO:0048147=IDA, GO:0006880=IDA, GO:0055085=TAS, GO:0008199=IEA, GO:0005829=TAS, GO:0006879=TAS, GO:0005739=IEA, GO:0008043=TAS, GO:0004322=IEA, GO:0006955=ISS, GO:0016491=IEA, GO:0006826=IEA, GO:0016044=TAS} cellular iron ion homeostasis, cellular membrane organization, immune response, intracellular sequestering of iron ion, iron ion transport, negative regulation of cell proliferation, negative regulation of fibroblast proliferation, post-Golgi vesicle-mediated transport, transmembrane transport cytosol, intracellular ferritin complex, mitochondrion ferric iron binding, ferroxidase activity, iron ion binding, oxidoreductase activity, protein binding Human UniProtKB:Q9UER7 FTL IntAct UniProtKB {GO:0005515=PMID:23275563, GO:0008219=GO_REF:0000037, GO:0005506=PMID:19923220, GO:0006892=Reactome:REACT_11235, GO:0055072=PMID:19923220, GO:0055085=Reactome:REACT_15518, GO:0042802=PMID:16790936, GO:0008199=GO_REF:0000002, GO:0005829=Reactome:REACT_115629, GO:0008043=PMID:20159981, GO:0006879=Reactome:REACT_25060, GO:0016491=GO_REF:0000002, GO:0006826=GO_REF:0000002, GO:0016044=Reactome:REACT_11123} P02792 Ferritin light chain protein 20130415 {GO:0005515=IPI, GO:0008219=IEA, GO:0005506=IDA, GO:0006892=TAS, GO:0055072=TAS, GO:0055085=TAS, GO:0042802=IPI, GO:0008199=IEA, GO:0005829=TAS, GO:0008043=IDA, GO:0006879=TAS, GO:0016491=IEA, GO:0006826=IEA, GO:0016044=TAS} cell death, cellular iron ion homeostasis, cellular membrane organization, iron ion homeostasis, iron ion transport, post-Golgi vesicle-mediated transport, transmembrane transport cytosol, intracellular ferritin complex ferric iron binding, identical protein binding, iron ion binding, oxidoreductase activity, protein binding Human UniProtKB:P02792 FTO BHF-UCL UniProtKB {GO:0001659=GO_REF:0000019, GO:0070989=PMID:18775698, GO:0043734=PMID:20376003, GO:0005634=PMID:17991826, GO:0010883=GO_REF:0000019, GO:0042245=PMID:18775698, GO:0035515=PMID:18775698, GO:0008198=PMID:20376003, GO:0035553=PMID:18775698, GO:0035516=PMID:18775698, GO:0035552=PMID:18775698, GO:0006307=PMID:18775698, GO:0040014=GO_REF:0000019, GO:0080111=PMID:18775698, GO:0070350=GO_REF:0000019, GO:0044065=GO_REF:0000019, GO:0016702=GO_REF:0000037, GO:0060612=GO_REF:0000019} Q9C0B1 Alpha-ketoglutarate-dependent dioxygenase FTO protein 20100517 {GO:0001659=IEA, GO:0070989=IDA, GO:0043734=IDA, GO:0005634=ISS, GO:0010883=IEA, GO:0042245=IDA, GO:0035515=IDA, GO:0008198=IDA, GO:0035553=IDA, GO:0035516=IDA, GO:0035552=IDA, GO:0006307=IDA, GO:0040014=IEA, GO:0080111=IDA, GO:0070350=IEA, GO:0044065=IEA, GO:0016702=IEA, GO:0060612=IEA} DNA dealkylation involved in DNA repair, DNA demethylation, RNA repair, adipose tissue development, oxidative demethylation, oxidative single-stranded DNA demethylation, oxidative single-stranded RNA demethylation, regulation of lipid storage, regulation of multicellular organism growth, regulation of respiratory system process, regulation of white fat cell proliferation, temperature homeostasis nucleus DNA-N1-methyladenine dioxygenase activity, ferrous iron binding, oxidative DNA demethylase activity, oxidative RNA demethylase activity, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Human FTSJ1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0001510=GO_REF:0000002, GO:0008168=GO_REF:0000037, GO:0008033=GO_REF:0000037} Q9UET6 Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase protein 20130413 {GO:0005737=IEA, GO:0001510=IEA, GO:0008168=IEA, GO:0008033=IEA} RNA methylation, tRNA processing cytoplasm methyltransferase activity Human UniProtKB-SubCell:SL-0086 FTSJ2 BHF-UCL UniProtKB {GO:0005739=GO_REF:0000024, GO:0031167=PMID:11827451, GO:0001510=GO_REF:0000002, GO:0008283=PMID:11827451, GO:0006364=PMID:11827451, GO:0008650=PMID:11827451, GO:0008168=GO_REF:0000002, GO:0005730=PMID:11827451} Q9UI43 Putative ribosomal RNA methyltransferase 2 protein 20110310 {GO:0005739=ISS, GO:0031167=NAS, GO:0001510=IEA, GO:0008283=NAS, GO:0006364=NAS, GO:0008650=NAS, GO:0008168=IEA, GO:0005730=IDA} RNA methylation, cell proliferation, rRNA methylation, rRNA processing mitochondrion, nucleolus methyltransferase activity, rRNA (uridine-2'-O-)-methyltransferase activity Human UniProtKB:Q9CPY0 FTSJ3 IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0001510=GO_REF:0000002, GO:0006364=GO_REF:0000037, GO:0008168=GO_REF:0000037, GO:0005730=GO_REF:0000039} Q8IY81 pre-rRNA processing protein FTSJ3 protein 20130415 {GO:0005515=IPI, GO:0001510=IEA, GO:0006364=IEA, GO:0008168=IEA, GO:0005730=IEA} RNA methylation, rRNA processing nucleolus methyltransferase activity, protein binding Human UniProtKB:Q9Y6K5 FTSJD1 UniProtKB UniProtKB {GO:0008168=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q8IYT2 FtsJ methyltransferase domain-containing protein 1 protein 20130413 {GO:0008168=IEA, GO:0016021=IEA} integral to membrane methyltransferase activity Human UniProtKB-KW:KW-0812 FTSJD2 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0004483=PMID:20713356, GO:0008168=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0006370=PMID:20713356, GO:0080009=PMID:20713356, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002} Q8N1G2 Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 protein 20101115 {GO:0005737=IDA, GO:0004483=IDA, GO:0008168=IEA, GO:0005730=IDA, GO:0006370=IMP, GO:0080009=IDA, GO:0005634=IDA, GO:0003676=IEA} 7-methylguanosine mRNA capping, mRNA methylation cytoplasm, nucleolus, nucleus mRNA (nucleoside-2'-O-)-methyltransferase activity, methyltransferase activity, nucleic acid binding Human FUBP1 HPA UniProtKB {GO:0003700=PMID:8125259, GO:0006366=PMID:8125259, GO:0003697=PMID:8125259, GO:0003723=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q96AE4 Far upstream element-binding protein 1 protein 20080205 {GO:0003700=TAS, GO:0006366=TAS, GO:0003697=TAS, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA} transcription from RNA polymerase II promoter nucleolus, nucleus RNA binding, sequence-specific DNA binding transcription factor activity, single-stranded DNA binding NOT Human FUBP3 UniProtKB UniProtKB {GO:0005737=PMID:19087307, GO:0003723=GO_REF:0000002, GO:0005634=PMID:8940189, GO:0045893=PMID:8940189, GO:0003677=GO_REF:0000037, GO:0006351=PMID:8940189} Q96I24 Far upstream element-binding protein 3 protein 20111118 {GO:0005737=IDA, GO:0003723=IEA, GO:0005634=NAS, GO:0045893=IDA, GO:0003677=IEA, GO:0006351=IDA} positive regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus DNA binding, RNA binding Human FUCA1 UniProtKB UniProtKB {GO:0005737=PMID:11698403, GO:0004560=PMID:11698403, GO:0006027=PMID:11698403, GO:0030246=GO_REF:0000019, GO:0006004=GO_REF:0000002, GO:0005764=GO_REF:0000039} P04066 Tissue alpha-L-fucosidase protein 20031216 {GO:0005737=IC, GO:0004560=TAS, GO:0006027=NAS, GO:0030246=IEA, GO:0006004=IEA, GO:0005764=IEA} fucose metabolic process, glycosaminoglycan catabolic process cytoplasm, lysosome alpha-L-fucosidase activity, carbohydrate binding Human FUCA2 UniProtKB UniProtKB {GO:0005975=GO_REF:0000002, GO:0004560=GO_REF:0000003, GO:0005576=GO_REF:0000039, GO:0006004=GO_REF:0000002} Q9BTY2 Plasma alpha-L-fucosidase protein 20130413 {GO:0005975=IEA, GO:0004560=IEA, GO:0005576=IEA, GO:0006004=IEA} carbohydrate metabolic process, fucose metabolic process extracellular region alpha-L-fucosidase activity Human UniProtKB-SubCell:SL-0243 FUK UniProtKB UniProtKB {GO:0005737=GO_REF:0000002, GO:0050201=PMID:12056818, GO:0016301=GO_REF:0000038, GO:0016773=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0016772=GO_REF:0000002} Q8N0W3 L-fucose kinase protein 20041109 {GO:0005737=IEA, GO:0050201=NAS, GO:0016301=IEA, GO:0016773=IEA, GO:0005524=IEA, GO:0016772=IEA} cytoplasm ATP binding, fucokinase activity, kinase activity, phosphotransferase activity, alcohol group as acceptor, transferase activity, transferring phosphorus-containing groups Human FUNDC1 MGI UniProtKB {GO:0005515=PMID:22267086, GO:0001666=PMID:22267086, GO:0000422=PMID:22267086, GO:0005741=PMID:22267086, GO:0031307=PMID:22267086} Q8IVP5 FUN14 domain-containing protein 1 protein 20120727 {GO:0005515=IPI, GO:0001666=IMP, GO:0000422=IMP, GO:0005741=IDA, GO:0031307=IDA} mitochondrion degradation, response to hypoxia integral to mitochondrial outer membrane, mitochondrial outer membrane protein binding Human FUNDC2 LIFEdb UniProtKB {GO:0005739=GO_REF:0000054} Q9BWH2 FUN14 domain-containing protein 2 protein 20100607 {GO:0005739=IDA} mitochondrion Human FURIN BHF-UCL UniProtKB {GO:0005802=PMID:14744861, GO:0032455=Reactome:REACT_11062, GO:0051044=PMID:17010968, GO:0005886=Reactome:REACT_150355, GO:0004252=PMID:10567353, GO:0004867=PMID:10567353, GO:0008283=PMID:15899807, GO:0002020=PMID:14744861, GO:0032911=PMID:15899807, GO:0005615=PMID:10567353, GO:0052548=PMID:14744861, GO:0046872=GO_REF:0000037, GO:0016486=PMID:9242664, GO:0007219=Reactome:REACT_299, GO:0022617=Reactome:REACT_118572, GO:0016485=PMID:14744861, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0006508=Reactome:REACT_733, GO:0007179=Reactome:REACT_120850, GO:0030140=PMID:15078902, GO:0042277=PMID:8940009, GO:0048011=Reactome:REACT_11061, GO:0009986=PMID:16537537, GO:0042176=PMID:15899807, GO:0019067=PMID:8940009, GO:0048406=PMID:8615794, GO:0005796=Reactome:REACT_10058, GO:0043043=PMID:8262946, GO:0032902=PMID:8615794, GO:0009966=GO_REF:0000019, GO:0032904=PMID:10567353, GO:0017187=Reactome:REACT_1132, GO:0004175=PMID:9242664, GO:0000139=Reactome:REACT_118833, GO:0032804=PMID:16912035, GO:0008233=PMID:15082773, GO:0045121=PMID:17010968, GO:0016021=GO_REF:0000037, GO:0032940=PMID:8615794, GO:0044267=Reactome:REACT_17015, GO:0006465=PMID:16912035, GO:0043687=Reactome:REACT_22161} P09958 Furin protein 20080415 {GO:0005802=IDA, GO:0032455=TAS, GO:0051044=IC, GO:0005886=TAS, GO:0004252=IDA, GO:0004867=IDA, GO:0008283=IMP, GO:0002020=IPI, GO:0032911=IMP, GO:0005615=IDA, GO:0052548=IDA, GO:0046872=IEA, GO:0016486=IDA, GO:0007219=TAS, GO:0022617=TAS, GO:0016485=IDA, GO:0030198=TAS, GO:0030574=TAS, GO:0006508=TAS, GO:0007179=TAS, GO:0030140=IDA, GO:0042277=IDA, GO:0048011=TAS, GO:0009986=IDA, GO:0042176=IMP, GO:0019067=IEP, GO:0048406=IDA, GO:0005796=TAS, GO:0043043=IDA, GO:0032902=IDA, GO:0009966=IEA, GO:0032904=IDA, GO:0017187=TAS, GO:0004175=IDA, GO:0000139=TAS, GO:0032804=IDA, GO:0008233=IDA, GO:0045121=IDA, GO:0016021=IEA, GO:0032940=IDA, GO:0044267=TAS, GO:0006465=IDA, GO:0043687=TAS} Notch signaling pathway, cell proliferation, cellular protein metabolic process, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, negative regulation of low-density lipoprotein particle receptor catabolic process, negative regulation of nerve growth factor production, negative regulation of transforming growth factor beta1 production, nerve growth factor processing, nerve growth factor production, neurotrophin TRK receptor signaling pathway, peptide biosynthetic process, peptide hormone processing, peptidyl-glutamic acid carboxylation, positive regulation of membrane protein ectodomain proteolysis, post-translational protein modification, protein processing, proteolysis, regulation of endopeptidase activity, regulation of protein catabolic process, regulation of signal transduction, secretion by cell, signal peptide processing, transforming growth factor beta receptor signaling pathway, viral assembly, maturation, egress, and release Golgi lumen, Golgi membrane, cell surface, extracellular space, integral to membrane, membrane raft, plasma membrane, trans-Golgi network, trans-Golgi network transport vesicle endopeptidase activity, metal ion binding, nerve growth factor binding, peptidase activity, peptide binding, protease binding, serine-type endopeptidase activity, serine-type endopeptidase inhibitor activity Human FUS HPA UniProtKB {GO:0005515=PMID:20085233, GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0008219=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000019, GO:0000166=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_1935} P35637 RNA-binding protein FUS protein 20080205 {GO:0005515=IPI, GO:0008380=TAS, GO:0010467=TAS, GO:0008219=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0003677=IEA, GO:0005622=IEA, GO:0005737=IEA, GO:0000166=IEA, GO:0000398=TAS, GO:0008270=IEA, GO:0005654=TAS} RNA splicing, cell death, gene expression, mRNA splicing, via spliceosome cytoplasm, intracellular, nucleolus, nucleoplasm, nucleus DNA binding, RNA binding, nucleic acid binding, nucleotide binding, protein binding, zinc ion binding NOT Human FUT1 PINC UniProtKB {GO:0042355=PMID:11698403, GO:0005794=PMID:11698403, GO:0016020=PMID:2118655, GO:0005975=PMID:2118655, GO:0005887=PMID:2118655, GO:0008417=PMID:2118655, GO:0008107=PMID:11698403, GO:0032580=GO_REF:0000039, GO:0006486=PMID:11698403} P19526 Galactoside 2-alpha-L-fucosyltransferase 1 protein 20030904 {GO:0042355=NAS, GO:0005794=TAS, GO:0016020=TAS, GO:0005975=TAS, GO:0005887=TAS, GO:0008417=TAS, GO:0008107=TAS, GO:0032580=IEA, GO:0006486=TAS} L-fucose catabolic process, carbohydrate metabolic process, protein glycosylation Golgi apparatus, Golgi cisterna membrane, integral to plasma membrane, membrane fucosyltransferase activity, galactoside 2-alpha-L-fucosyltransferase activity Human FUT10 UniProtKB UniProtKB {GO:0030097=PMID:11698403, GO:0046920=PMID:11698403, GO:0042355=PMID:11698403, GO:0005794=PMID:11698403, GO:0009790=PMID:11698403, GO:0006605=PMID:11698403, GO:0007399=PMID:11698403, GO:0009566=PMID:11698403, GO:0006457=PMID:11698403, GO:0032580=GO_REF:0000039, GO:0042060=PMID:11698403, GO:0006486=PMID:11698403, GO:0016021=GO_REF:0000037} Q6P4F1 Alpha-(1,3)-fucosyltransferase 10 protein 20070906 {GO:0030097=NAS, GO:0046920=TAS, GO:0042355=NAS, GO:0005794=TAS, GO:0009790=NAS, GO:0006605=NAS, GO:0007399=NAS, GO:0009566=NAS, GO:0006457=NAS, GO:0032580=IEA, GO:0042060=NAS, GO:0006486=TAS, GO:0016021=IEA} L-fucose catabolic process, embryo development, fertilization, hemopoiesis, nervous system development, protein folding, protein glycosylation, protein targeting, wound healing Golgi apparatus, Golgi cisterna membrane, integral to membrane alpha-(1->3)-fucosyltransferase activity Human FUT11 UniPathway UniProtKB {GO:0046920=GO_REF:0000002, GO:0032580=GO_REF:0000039, GO:0006486=GO_REF:0000041, GO:0016021=GO_REF:0000037} Q495W5 Alpha-(1,3)-fucosyltransferase 11 protein 20130413 {GO:0046920=IEA, GO:0032580=IEA, GO:0006486=IEA, GO:0016021=IEA} protein glycosylation Golgi cisterna membrane, integral to membrane alpha-(1->3)-fucosyltransferase activity Human UniPathway:UPA00378 FUT4 GOC UniProtKB {GO:0042355=PMID:11698403, GO:0046920=PMID:11698403, GO:0005794=PMID:11698403, GO:0016020=PMID:1716630, GO:0009986=GO_REF:0000019, GO:0005975=PMID:1716630, GO:0008417=PMID:1716630, GO:0032580=GO_REF:0000039, GO:0006486=PMID:11698403, GO:0016021=GO_REF:0000037, GO:0036065=PMID:1716630, GO:0071944=GO_REF:0000019} P22083 Alpha-(1,3)-fucosyltransferase protein 20130413 {GO:0042355=NAS, GO:0046920=TAS, GO:0005794=TAS, GO:0016020=TAS, GO:0009986=IEA, GO:0005975=TAS, GO:0008417=TAS, GO:0032580=IEA, GO:0006486=TAS, GO:0016021=IEA, GO:0036065=TAS, GO:0071944=IEA} L-fucose catabolic process, carbohydrate metabolic process, fucosylation, protein glycosylation Golgi apparatus, Golgi cisterna membrane, cell periphery, cell surface, integral to membrane, membrane alpha-(1->3)-fucosyltransferase activity, fucosyltransferase activity Human FUT7 GOC UniProtKB {GO:0042355=PMID:11698403, GO:0046920=PMID:11698403, GO:0005794=PMID:11698403, GO:0008417=PMID:8207002, GO:0032580=GO_REF:0000039, GO:0002522=GO_REF:0000019, GO:0002361=GO_REF:0000019, GO:0006486=PMID:11698403, GO:0016021=GO_REF:0000037, GO:0036065=PMID:8207002} Q11130 Alpha-(1,3)-fucosyltransferase protein 20130413 {GO:0042355=NAS, GO:0046920=TAS, GO:0005794=TAS, GO:0008417=TAS, GO:0032580=IEA, GO:0002522=IEA, GO:0002361=IEA, GO:0006486=TAS, GO:0016021=IEA, GO:0036065=TAS} CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation, L-fucose catabolic process, fucosylation, leukocyte migration involved in immune response, protein glycosylation Golgi apparatus, Golgi cisterna membrane, integral to membrane alpha-(1->3)-fucosyltransferase activity, fucosyltransferase activity Human FUT8 GOC UniProtKB {GO:0036071=PMID:9133635, GO:0042355=PMID:11698403, GO:0009312=PMID:9133635, GO:0017124=GO_REF:0000037, GO:0005794=PMID:11698403, GO:0007585=GO_REF:0000019, GO:0016757=GO_REF:0000038, GO:0046921=GO_REF:0000019, GO:0033578=GO_REF:0000002, GO:0001701=PMID:11698403, GO:0000139=Reactome:REACT_25399, GO:0016477=GO_REF:0000019, GO:0007229=GO_REF:0000019, GO:0006491=PMID:11698403, GO:0032580=GO_REF:0000039, GO:0007179=GO_REF:0000019, GO:0043112=GO_REF:0000019, GO:0006487=PMID:9133635, GO:0016021=GO_REF:0000037, GO:0008424=PMID:11698403, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q9BYC5 Alpha-(1,6)-fucosyltransferase protein 20130413 {GO:0036071=TAS, GO:0042355=NAS, GO:0009312=TAS, GO:0017124=IEA, GO:0005794=NAS, GO:0007585=IEA, GO:0016757=IEA, GO:0046921=IEA, GO:0033578=IEA, GO:0001701=NAS, GO:0000139=TAS, GO:0016477=IEA, GO:0007229=IEA, GO:0006491=TAS, GO:0032580=IEA, GO:0007179=IEA, GO:0043112=IEA, GO:0006487=TAS, GO:0016021=IEA, GO:0008424=TAS, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS} L-fucose catabolic process, N-glycan fucosylation, N-glycan processing, cell migration, cellular protein metabolic process, in utero embryonic development, integrin-mediated signaling pathway, oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation, protein N-linked glycosylation via asparagine, protein glycosylation in Golgi, receptor metabolic process, respiratory gaseous exchange, transforming growth factor beta receptor signaling pathway Golgi apparatus, Golgi cisterna membrane, Golgi membrane, integral to membrane SH3 domain binding, alpha-(1->6)-fucosyltransferase activity, glycoprotein 6-alpha-L-fucosyltransferase activity, transferase activity, transferring glycosyl groups Human FUT9 GOC UniProtKB {GO:0042355=PMID:11698403, GO:0046920=PMID:11698403, GO:0005794=PMID:11698403, GO:0005975=PMID:10386598, GO:0008417=PMID:10386598, GO:0032580=GO_REF:0000039, GO:0006486=PMID:11698403, GO:0016021=GO_REF:0000037, GO:0036065=PMID:10386598, GO:0007399=GO_REF:0000019} Q9Y231 Alpha-(1,3)-fucosyltransferase protein 20130413 {GO:0042355=NAS, GO:0046920=TAS, GO:0005794=TAS, GO:0005975=TAS, GO:0008417=TAS, GO:0032580=IEA, GO:0006486=TAS, GO:0016021=IEA, GO:0036065=TAS, GO:0007399=IEA} L-fucose catabolic process, carbohydrate metabolic process, fucosylation, nervous system development, protein glycosylation Golgi apparatus, Golgi cisterna membrane, integral to membrane alpha-(1->3)-fucosyltransferase activity, fucosyltransferase activity Human FUZ UniProtKB UniProtKB {GO:0001736=GO_REF:0000024, GO:0042384=GO_REF:0000024, GO:0010172=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0008589=GO_REF:0000024, GO:0001843=GO_REF:0000024, GO:0048704=GO_REF:0000024, GO:0005856=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0001942=GO_REF:0000024} Q9BT04 Protein fuzzy homolog protein 20110413 {GO:0001736=ISS, GO:0042384=ISS, GO:0010172=ISS, GO:0005737=IEA, GO:0008589=ISS, GO:0001843=ISS, GO:0048704=ISS, GO:0005856=IEA, GO:0015031=IEA, GO:0001942=ISS} cilium assembly, embryonic body morphogenesis, embryonic skeletal system morphogenesis, establishment of planar polarity, hair follicle development, neural tube closure, protein transport, regulation of smoothened signaling pathway cytoplasm, cytoskeleton Human UniProtKB:Q3UYI6 FXN BHF-UCL UniProtKB {GO:0005515=PMID:15123683, GO:0014070=GO_REF:0000019, GO:0008284=PMID:18160053, GO:0016540=PMID:12785837, GO:0051353=PMID:18160053, GO:0070301=PMID:15641778, GO:0016226=GO_REF:0000002, GO:0030307=PMID:15509595, GO:0045773=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0009792=GO_REF:0000019, GO:0005829=PMID:17468497, GO:0006119=GO_REF:0000019, GO:0005739=PMID:17468497, GO:0009060=GO_REF:0000019, GO:0006879=PMID:18160053, GO:0040015=GO_REF:0000019, GO:0090201=PMID:16608849, GO:0005759=GO_REF:0000024, GO:0010039=PMID:18424449, GO:0007628=GO_REF:0000019, GO:0006811=GO_REF:0000037, GO:0046621=GO_REF:0000019, GO:0010722=PMID:15123683, GO:0034986=PMID:15123683, GO:0043066=PMID:16608849, GO:0019230=GO_REF:0000019, GO:0051536=PMID:17285345, GO:0051537=PMID:12785837, GO:0042493=GO_REF:0000019, GO:0051349=PMID:18160053, GO:0051347=PMID:18160053, GO:0008198=PMID:15123683, GO:0006783=PMID:15123683, GO:0008199=PMID:18537827, GO:0004322=PMID:15641778, GO:0048554=PMID:15509595, GO:0007005=GO_REF:0000019, GO:0019899=GO_REF:0000019, GO:0018283=PMID:12785837} Q16595 Frataxin, mitochondrial protein 20080912 {GO:0005515=IPI, GO:0014070=IEA, GO:0008284=IMP, GO:0016540=IDA, GO:0051353=IMP, GO:0070301=IDA, GO:0016226=IEA, GO:0030307=IMP, GO:0045773=IEA, GO:0044281=TAS, GO:0009792=IEA, GO:0005829=IDA, GO:0006119=IEA, GO:0005739=IDA, GO:0009060=IEA, GO:0006879=IMP, GO:0040015=IEA, GO:0090201=IMP, GO:0005759=ISS, GO:0010039=IMP, GO:0007628=IEA, GO:0006811=IEA, GO:0046621=IEA, GO:0010722=IDA, GO:0034986=IDA, GO:0043066=IMP, GO:0019230=IEA, GO:0051536=IDA, GO:0051537=IDA, GO:0042493=IEA, GO:0051349=IMP, GO:0051347=IMP, GO:0008198=IDA, GO:0006783=NAS, GO:0008199=IDA, GO:0004322=IDA, GO:0048554=IMP, GO:0007005=IEA, GO:0019899=IEA, GO:0018283=IDA} adult walking behavior, aerobic respiration, cellular iron ion homeostasis, cellular response to hydrogen peroxide, embryo development ending in birth or egg hatching, heme biosynthetic process, ion transport, iron incorporation into metallo-sulfur cluster, iron-sulfur cluster assembly, mitochondrion organization, negative regulation of apoptotic process, negative regulation of multicellular organism growth, negative regulation of organ growth, negative regulation of release of cytochrome c from mitochondria, oxidative phosphorylation, positive regulation of axon extension, positive regulation of cell growth, positive regulation of cell proliferation, positive regulation of lyase activity, positive regulation of metalloenzyme activity, positive regulation of oxidoreductase activity, positive regulation of transferase activity, proprioception, protein autoprocessing, regulation of ferrochelatase activity, response to drug, response to iron ion, response to organic cyclic compound, small molecule metabolic process cytosol, mitochondrial matrix, mitochondrion 2 iron, 2 sulfur cluster binding, enzyme binding, ferric iron binding, ferrous iron binding, ferroxidase activity, iron chaperone activity, iron-sulfur cluster binding, protein binding Human FXR1 HPA UniProtKB {GO:0017148=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0007517=GO_REF:0000037, GO:0002151=GO_REF:0000019, GO:0003723=PMID:7781595, GO:0005730=PMID:10888599, GO:0043034=GO_REF:0000019, GO:0006915=PMID:9642279, GO:0005634=GO_REF:0000019, GO:0003730=GO_REF:0000019, GO:0005844=GO_REF:0000019, GO:0030154=GO_REF:0000037} P51114 Fragile X mental retardation syndrome-related protein 1 protein 20090616 {GO:0017148=IEA, GO:0005737=IDA, GO:0007517=IEA, GO:0002151=IEA, GO:0003723=TAS, GO:0005730=TAS, GO:0043034=IEA, GO:0006915=TAS, GO:0005634=IEA, GO:0003730=IEA, GO:0005844=IEA, GO:0030154=IEA} apoptotic process, cell differentiation, muscle organ development, negative regulation of translation costamere, cytoplasm, nucleolus, nucleus, polysome G-quadruplex RNA binding, RNA binding, mRNA 3'-UTR binding Human FXR2 HPA UniProtKB {GO:0005515=PMID:19060904, GO:0005737=GO_REF:0000052, GO:0003723=GO_REF:0000037, GO:0022625=PMID:9259278} P51116 Fragile X mental retardation syndrome-related protein 2 protein 20100326 {GO:0005515=IPI, GO:0005737=IDA, GO:0003723=IEA, GO:0022625=TAS} cytoplasm, cytosolic large ribosomal subunit RNA binding, protein binding Human FXYD1 Reactome UniProtKB {GO:0006821=PMID:9169143, GO:0034220=Reactome:REACT_25300, GO:0006936=PMID:9169143, GO:0005886=Reactome:REACT_25287, GO:0016020=GO_REF:0000002, GO:0005887=PMID:9169143, GO:0034707=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000037, GO:0005216=GO_REF:0000002} O00168 Phospholemman protein 20130301 {GO:0006821=TAS, GO:0034220=TAS, GO:0006936=TAS, GO:0005886=TAS, GO:0016020=IEA, GO:0005887=TAS, GO:0034707=IEA, GO:0055085=TAS, GO:0005254=IEA, GO:0005216=IEA} chloride transport, ion transmembrane transport, muscle contraction, transmembrane transport chloride channel complex, integral to plasma membrane, membrane, plasma membrane chloride channel activity, ion channel activity Human FXYD2 Reactome UniProtKB {GO:0005215=PMID:9048881, GO:0005886=Reactome:REACT_25287, GO:0005890=GO_REF:0000029, GO:0001558=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0043231=GO_REF:0000019, GO:0016323=GO_REF:0000019, GO:0034220=Reactome:REACT_25300, GO:0042127=GO_REF:0000019, GO:0006810=PMID:9048881, GO:0005216=GO_REF:0000029, GO:0005391=GO_REF:0000019, GO:0006811=GO_REF:0000029} P54710 Sodium/potassium-transporting ATPase subunit gamma protein 20130301 {GO:0005215=TAS, GO:0005886=TAS, GO:0005890=NAS, GO:0001558=IEA, GO:0055085=TAS, GO:0043231=IEA, GO:0016323=IEA, GO:0034220=TAS, GO:0042127=IEA, GO:0006810=TAS, GO:0005216=NAS, GO:0005391=IEA, GO:0006811=NAS} ion transmembrane transport, ion transport, regulation of cell growth, regulation of cell proliferation, transmembrane transport, transport basolateral plasma membrane, intracellular membrane-bounded organelle, plasma membrane, sodium:potassium-exchanging ATPase complex ion channel activity, sodium:potassium-exchanging ATPase activity, transporter activity Human FXYD3 Reactome UniProtKB {GO:0006821=PMID:7836447, GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_25287, GO:0016020=GO_REF:0000002, GO:0005887=PMID:7836447, GO:0034707=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000037, GO:0005216=GO_REF:0000002} Q14802 FXYD domain-containing ion transport regulator 3 protein 20130301 {GO:0006821=TAS, GO:0034220=TAS, GO:0005886=TAS, GO:0016020=IEA, GO:0005887=TAS, GO:0034707=IEA, GO:0055085=TAS, GO:0005254=IEA, GO:0005216=IEA} chloride transport, ion transmembrane transport, transmembrane transport chloride channel complex, integral to plasma membrane, membrane, plasma membrane chloride channel activity, ion channel activity Human FXYD5 UniProtKB UniProtKB {GO:0045296=PMID:11756660, GO:0016020=GO_REF:0000002, GO:0030033=PMID:11756660, GO:0003779=PMID:11756660, GO:0046588=PMID:11756660, GO:0016021=PMID:11756660, GO:0005216=GO_REF:0000002} Q96DB9 FXYD domain-containing ion transport regulator 5 protein 20021029 {GO:0045296=IDA, GO:0016020=IEA, GO:0030033=NAS, GO:0003779=IDA, GO:0046588=NAS, GO:0016021=IDA, GO:0005216=IEA} microvillus assembly, negative regulation of calcium-dependent cell-cell adhesion integral to membrane, membrane actin binding, cadherin binding, ion channel activity Human FXYD6 LIFEdb UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0034220=Reactome:REACT_25300, GO:0005886=GO_REF:0000054, GO:0016020=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0005216=GO_REF:0000002} Q9H0Q3 FXYD domain-containing ion transport regulator 6 protein 20100607 {GO:0003674=ND, GO:0008150=ND, GO:0034220=TAS, GO:0005886=IDA, GO:0016020=IEA, GO:0016021=IEA, GO:0055085=TAS, GO:0005216=IEA} biological_process, ion transmembrane transport, transmembrane transport integral to membrane, membrane, plasma membrane ion channel activity, molecular_function Human FXYD7 Reactome UniProtKB {GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_25287, GO:0016020=GO_REF:0000002, GO:0051117=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0005216=GO_REF:0000002, GO:0043269=GO_REF:0000019} P58549 FXYD domain-containing ion transport regulator 7 protein 20130301 {GO:0034220=TAS, GO:0005886=TAS, GO:0016020=IEA, GO:0051117=IEA, GO:0016021=IEA, GO:0055085=TAS, GO:0005216=IEA, GO:0043269=IEA} ion transmembrane transport, regulation of ion transport, transmembrane transport integral to membrane, membrane, plasma membrane ATPase binding, ion channel activity Human FYB IntAct UniProtKB {GO:0005515=PMID:22074159, GO:0050852=Reactome:REACT_12526, GO:0005102=PMID:10747096, GO:0005634=GO_REF:0000039, GO:0015629=PMID:10747096, GO:0032403=GO_REF:0000019, GO:0006607=PMID:9207119, GO:0007243=PMID:9207119, GO:0005829=Reactome:REACT_23963, GO:0008150=GO_REF:0000015, GO:0007165=PMID:9207119, GO:0006955=PMID:9207119, GO:0006468=PMID:9207119} O15117 FYN-binding protein protein 20130415 {GO:0005515=IPI, GO:0050852=TAS, GO:0005102=TAS, GO:0005634=IEA, GO:0015629=TAS, GO:0032403=IEA, GO:0006607=TAS, GO:0007243=TAS, GO:0005829=TAS, GO:0008150=ND, GO:0007165=TAS, GO:0006955=TAS, GO:0006468=TAS} NLS-bearing substrate import into nucleus, T cell receptor signaling pathway, biological_process, immune response, intracellular protein kinase cascade, protein phosphorylation, signal transduction actin cytoskeleton, cytosol, nucleus protein binding, protein complex binding, receptor binding Human UniProtKB:P16333 FYCO1 IntAct UniProtKB {GO:0005515=PMID:20562859, GO:0005776=PMID:20100911, GO:0005770=PMID:20100911, GO:0006810=GO_REF:0000002, GO:0072383=PMID:20100911, GO:0031410=GO_REF:0000037, GO:0016021=GO_REF:0000002, GO:0005764=PMID:20100911, GO:0046872=GO_REF:0000037} Q9BQS8 FYVE and coiled-coil domain-containing protein 1 protein 20130415 {GO:0005515=IPI, GO:0005776=IDA, GO:0005770=IDA, GO:0006810=IEA, GO:0072383=IMP, GO:0031410=IEA, GO:0016021=IEA, GO:0005764=IDA, GO:0046872=IEA} plus-end-directed vesicle transport along microtubule, transport autophagic vacuole, cytoplasmic vesicle, integral to membrane, late endosome, lysosome metal ion binding, protein binding Human UniProtKB:Q9H0R8 FYN UniProtKB UniProtKB {GO:0005515=PMID:22939624, GO:0008360=GO_REF:0000019, GO:0050900=Reactome:REACT_12051, GO:0007243=PMID:1361685, GO:0042802=PMID:14993658, GO:0042608=GO_REF:0000019, GO:0001948=PMID:16831868, GO:0046777=GO_REF:0000019, GO:0042609=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0007411=Reactome:REACT_18266, GO:0007612=PMID:1361685, GO:0030168=Reactome:REACT_798, GO:0014069=GO_REF:0000019, GO:0018108=GO_REF:0000019, GO:0044325=GO_REF:0000019, GO:0046875=PMID:10498895, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0010976=GO_REF:0000019, GO:0038096=Reactome:REACT_160123, GO:0043548=GO_REF:0000019, GO:0050852=PMID:7722293, GO:0007631=PMID:8264796, GO:0005886=PMID:15611048, GO:0045471=GO_REF:0000019, GO:0031295=Reactome:REACT_19344, GO:0005634=GO_REF:0000039, GO:0051428=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_160304, GO:0005739=GO_REF:0000019, GO:0015631=GO_REF:0000019, GO:0071375=GO_REF:0000019, GO:2001240=GO_REF:0000019, GO:0016032=Reactome:REACT_6185, GO:0050966=GO_REF:0000019, GO:0006816=PMID:7822789, GO:0048011=Reactome:REACT_11061, GO:0042610=GO_REF:0000019, GO:0042177=GO_REF:0000019, GO:0048015=Reactome:REACT_12464, GO:0042493=GO_REF:0000019, GO:0005524=GO_REF:0000038, GO:0050690=Reactome:REACT_11068, GO:0048813=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0071363=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0019048=GO_REF:0000037, GO:0010629=GO_REF:0000019, GO:0050798=GO_REF:0000019, GO:0006468=PMID:7822789, GO:0030900=GO_REF:0000019, GO:0004713=GO_REF:0000038, GO:0001764=GO_REF:0000019, GO:0004715=PMID:7822789, GO:0007166=GO_REF:0000019, GO:0005768=PMID:15611048} Q5R3A8 Tyrosine-protein kinase Fyn protein 20130413 {GO:0005515=IPI, GO:0008360=IEA, GO:0050900=TAS, GO:0007243=TAS, GO:0042802=IPI, GO:0042608=IEA, GO:0001948=IPI, GO:0046777=IEA, GO:0042609=IEA, GO:0007173=TAS, GO:0007411=TAS, GO:0007612=TAS, GO:0030168=TAS, GO:0014069=IEA, GO:0018108=IEA, GO:0044325=IEA, GO:0046875=IPI, GO:0008543=TAS, GO:0045087=TAS, GO:0010976=IEA, GO:0038096=TAS, GO:0043548=IEA, GO:0050852=IDA, GO:0007631=TAS, GO:0005886=IDA, GO:0045471=IEA, GO:0031295=TAS, GO:0005634=IEA, GO:0051428=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0015631=IEA, GO:0071375=IEA, GO:2001240=IEA, GO:0016032=TAS, GO:0050966=IEA, GO:0006816=NAS, GO:0048011=TAS, GO:0042610=IEA, GO:0042177=IEA, GO:0048015=TAS, GO:0042493=IEA, GO:0005524=IEA, GO:0050690=TAS, GO:0048813=IEA, GO:0016020=IEA, GO:0071363=IEA, GO:0007596=TAS, GO:0019048=IEA, GO:0010629=IEA, GO:0050798=IEA, GO:0006468=NAS, GO:0030900=IEA, GO:0004713=IEA, GO:0001764=IEA, GO:0004715=NAS, GO:0007166=IEA, GO:0005768=IDA} Fc-gamma receptor signaling pathway involved in phagocytosis, T cell costimulation, T cell receptor signaling pathway, activated T cell proliferation, axon guidance, blood coagulation, calcium ion transport, cell surface receptor signaling pathway, cellular response to growth factor stimulus, cellular response to peptide hormone stimulus, dendrite morphogenesis, detection of mechanical stimulus involved in sensory perception of pain, epidermal growth factor receptor signaling pathway, feeding behavior, fibroblast growth factor receptor signaling pathway, forebrain development, innate immune response, intracellular protein kinase cascade, learning, leukocyte migration, negative regulation of extrinsic apoptotic signaling pathway in absence of ligand, negative regulation of gene expression, negative regulation of protein catabolic process, neuron migration, neurotrophin TRK receptor signaling pathway, peptidyl-tyrosine phosphorylation, phosphatidylinositol-mediated signaling, platelet activation, positive regulation of neuron projection development, protein autophosphorylation, protein phosphorylation, regulation of cell shape, regulation of defense response to virus by virus, response to drug, response to ethanol, viral reproduction, virus-host interaction cytosol, endosome, membrane, mitochondrion, nucleus, plasma membrane, postsynaptic density ATP binding, CD4 receptor binding, CD8 receptor binding, T cell receptor binding, ephrin receptor binding, glycoprotein binding, identical protein binding, ion channel binding, metal ion binding, non-membrane spanning protein tyrosine kinase activity, peptide hormone receptor binding, phosphatidylinositol 3-kinase binding, protein binding, protein tyrosine kinase activity, tubulin binding Human UniProtKB-KW:KW-0067 FYTTD1 UniProtKB UniProtKB {GO:0005515=PMID:19836239, GO:0006406=PMID:19836239, GO:0016607=PMID:19836239, GO:0005654=PMID:19836239, GO:0003729=PMID:19836239} Q96QD9 UAP56-interacting factor protein 20091203 {GO:0005515=IPI, GO:0006406=IMP, GO:0016607=IDA, GO:0005654=IDA, GO:0003729=IDA} mRNA export from nucleus nuclear speck, nucleoplasm mRNA binding, protein binding Human FZD1 BHF-UCL UniProtKB {GO:0008406=GO_REF:0000033, GO:0005515=PMID:19277043, GO:0017147=PMID:10557084, GO:0007199=GO_REF:0000033, GO:0007267=PMID:10557084, GO:0044339=PMID:20039315, GO:0044338=PMID:20039315, GO:0007409=GO_REF:0000033, GO:0009790=GO_REF:0000033, GO:0035414=GO_REF:0000019, GO:0007223=GO_REF:0000033, GO:0030514=GO_REF:0000033, GO:0051091=PMID:14739301, GO:0005737=GO_REF:0000033, GO:0030182=GO_REF:0000024, GO:0030855=GO_REF:0000033, GO:0060070=PMID:14739301, GO:0090090=GO_REF:0000033, GO:0060022=GO_REF:0000019, GO:0001944=GO_REF:0000033, GO:0042813=PMID:10557084, GO:0003150=GO_REF:0000019, GO:0009986=PMID:19643732, GO:0048286=GO_REF:0000033, GO:0004930=GO_REF:0000037, GO:0042493=PMID:19421142, GO:0005102=PMID:14739301, GO:0090179=GO_REF:0000019, GO:0045177=GO_REF:0000033, GO:0035425=PMID:10557084, GO:0030165=PMID:19388021, GO:0032589=GO_REF:0000033, GO:0003151=GO_REF:0000019, GO:0007420=GO_REF:0000033, GO:0003149=GO_REF:0000019, GO:0001934=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0045893=PMID:18929644, GO:0045892=GO_REF:0000019} Q9UP38 Frizzled-1 protein 20100930 {GO:0008406=IBA, GO:0005515=IPI, GO:0017147=IPI, GO:0007199=IBA, GO:0007267=IDA, GO:0044339=IMP, GO:0044338=IMP, GO:0007409=IBA, GO:0009790=IBA, GO:0035414=IEA, GO:0007223=IBA, GO:0030514=IBA, GO:0051091=IDA, GO:0005737=IBA, GO:0030182=ISS, GO:0030855=IBA, GO:0060070=IDA, GO:0090090=IBA, GO:0060022=IEA, GO:0001944=IBA, GO:0042813=IDA, GO:0003150=IEA, GO:0009986=IDA, GO:0048286=IBA, GO:0004930=IEA, GO:0042493=IMP, GO:0005102=IPI, GO:0090179=IEA, GO:0045177=IBA, GO:0035425=IDA, GO:0030165=IPI, GO:0032589=IBA, GO:0003151=IEA, GO:0007420=IBA, GO:0003149=IEA, GO:0001934=IEA, GO:0016021=IEA, GO:0045893=IDA, GO:0045892=IEA} G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger, Wnt receptor signaling pathway, calcium modulating pathway, autocrine signaling, axonogenesis, brain development, canonical Wnt receptor signaling pathway, canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation, canonical Wnt receptor signaling pathway involved in osteoblast differentiation, cell-cell signaling, embryo development, epithelial cell differentiation, gonad development, hard palate development, lung alveolus development, membranous septum morphogenesis, muscular septum morphogenesis, negative regulation of BMP signaling pathway, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of catenin import into nucleus, negative regulation of transcription, DNA-dependent, neuron differentiation, outflow tract morphogenesis, planar cell polarity pathway involved in neural tube closure, positive regulation of protein phosphorylation, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription, DNA-dependent, response to drug, vasculature development apical part of cell, cell surface, cytoplasm, integral to membrane, neuron projection membrane G-protein coupled receptor activity, PDZ domain binding, Wnt-activated receptor activity, Wnt-protein binding, protein binding, receptor binding Human FZD10 BHF-UCL UniProtKB {GO:0005515=PMID:15930302, GO:0008406=GO_REF:0000033, GO:0042813=GO_REF:0000033, GO:0017147=GO_REF:0000033, GO:0009986=PMID:18271942, GO:0005886=GO_REF:0000033, GO:0034259=PMID:19137009, GO:0004930=GO_REF:0000037, GO:0071300=GO_REF:0000024, GO:0038031=PMID:19137009, GO:0009790=GO_REF:0000033, GO:0042995=GO_REF:0000033, GO:0030165=GO_REF:0000033, GO:0032855=PMID:19137009, GO:0005737=PMID:16007199, GO:0005887=PMID:10448064, GO:0007420=GO_REF:0000033, GO:0032956=PMID:19137009, GO:0030182=GO_REF:0000024, GO:0043507=PMID:19137009, GO:0060070=GO_REF:0000033, GO:0001944=GO_REF:0000033} Q9ULW2 Frizzled-10 protein 20120404 {GO:0005515=IPI, GO:0008406=IBA, GO:0042813=IBA, GO:0017147=IBA, GO:0009986=IDA, GO:0005886=IBA, GO:0034259=IMP, GO:0004930=IEA, GO:0071300=ISS, GO:0038031=IMP, GO:0009790=IBA, GO:0042995=IBA, GO:0030165=IBA, GO:0032855=IMP, GO:0005737=IDA, GO:0005887=TAS, GO:0007420=IBA, GO:0032956=IMP, GO:0030182=ISS, GO:0043507=IMP, GO:0060070=IBA, GO:0001944=IBA} brain development, canonical Wnt receptor signaling pathway, cellular response to retinoic acid, embryo development, gonad development, negative regulation of Rho GTPase activity, neuron differentiation, non-canonical Wnt receptor signaling pathway via JNK cascade, positive regulation of JUN kinase activity, positive regulation of Rac GTPase activity, regulation of actin cytoskeleton organization, vasculature development cell projection, cell surface, cytoplasm, integral to plasma membrane, plasma membrane G-protein coupled receptor activity, PDZ domain binding, Wnt-activated receptor activity, Wnt-protein binding, protein binding Human FZD2 BHF-UCL UniProtKB {GO:0008406=GO_REF:0000033, GO:0007608=GO_REF:0000019, GO:0017147=GO_REF:0000033, GO:0005886=PMID:18929644, GO:0007199=GO_REF:0000033, GO:0007267=GO_REF:0000019, GO:0007409=GO_REF:0000033, GO:0009790=GO_REF:0000033, GO:0007223=GO_REF:0000033, GO:0005737=PMID:19038973, GO:0051091=PMID:18929644, GO:0030182=GO_REF:0000024, GO:0030855=GO_REF:0000033, GO:0090103=GO_REF:0000019, GO:0060070=PMID:18215320, GO:0060022=GO_REF:0000019, GO:0001944=GO_REF:0000033, GO:0042813=GO_REF:0000033, GO:0003150=GO_REF:0000019, GO:0004930=GO_REF:0000037, GO:0090179=GO_REF:0000019, GO:0060119=GO_REF:0000019, GO:0045177=GO_REF:0000033, GO:0032589=GO_REF:0000033, GO:0030165=PMID:19388021, GO:0003151=GO_REF:0000019, GO:0007420=GO_REF:0000033, GO:0003149=GO_REF:0000019, GO:0030825=PMID:19946729, GO:0016021=GO_REF:0000037, GO:0045893=PMID:18215320} Q14332 Frizzled-2 protein 20100818 {GO:0008406=IBA, GO:0007608=IEA, GO:0017147=IBA, GO:0005886=IDA, GO:0007199=IBA, GO:0007267=IEA, GO:0007409=IBA, GO:0009790=IBA, GO:0007223=IBA, GO:0005737=IDA, GO:0051091=IDA, GO:0030182=ISS, GO:0030855=IBA, GO:0090103=IEA, GO:0060070=IDA, GO:0060022=IEA, GO:0001944=IBA, GO:0042813=IBA, GO:0003150=IEA, GO:0004930=IEA, GO:0090179=IEA, GO:0060119=IEA, GO:0045177=IBA, GO:0032589=IBA, GO:0030165=IPI, GO:0003151=IEA, GO:0007420=IBA, GO:0003149=IEA, GO:0030825=IMP, GO:0016021=IEA, GO:0045893=IDA} G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger, Wnt receptor signaling pathway, calcium modulating pathway, axonogenesis, brain development, canonical Wnt receptor signaling pathway, cell-cell signaling, cochlea morphogenesis, embryo development, epithelial cell differentiation, gonad development, hard palate development, inner ear receptor cell development, membranous septum morphogenesis, muscular septum morphogenesis, neuron differentiation, outflow tract morphogenesis, planar cell polarity pathway involved in neural tube closure, positive regulation of cGMP metabolic process, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription, DNA-dependent, sensory perception of smell, vasculature development apical part of cell, cytoplasm, integral to membrane, neuron projection membrane, plasma membrane G-protein coupled receptor activity, PDZ domain binding, Wnt-activated receptor activity, Wnt-protein binding Human FZD3 BHF-UCL UniProtKB {GO:0001736=GO_REF:0000033, GO:0008406=GO_REF:0000033, GO:0005515=PMID:19277043, GO:0017147=PMID:19038973, GO:0030424=GO_REF:0000033, GO:0005886=PMID:19038973, GO:0071679=GO_REF:0000033, GO:0007199=GO_REF:0000033, GO:0030425=GO_REF:0000033, GO:0005737=PMID:19038973, GO:0033278=GO_REF:0000033, GO:0016324=GO_REF:0000019, GO:0030182=GO_REF:0000024, GO:0043025=GO_REF:0000033, GO:0060070=PMID:20802536, GO:0001942=GO_REF:0000019, GO:0001944=GO_REF:0000033, GO:0042813=PMID:19038973, GO:0048786=GO_REF:0000033, GO:0042472=GO_REF:0000033, GO:0004930=GO_REF:0000037, GO:0001843=GO_REF:0000033, GO:0045177=GO_REF:0000033, GO:0032589=GO_REF:0000033, GO:0030165=PMID:18256285, GO:0036342=GO_REF:0000019, GO:0021754=GO_REF:0000033, GO:0016021=GO_REF:0000037, GO:0001764=GO_REF:0000019} Q9NPG1 Frizzled-3 protein 20100818 {GO:0001736=IBA, GO:0008406=IBA, GO:0005515=IPI, GO:0017147=IPI, GO:0030424=IBA, GO:0005886=IDA, GO:0071679=IBA, GO:0007199=IBA, GO:0030425=IBA, GO:0005737=IDA, GO:0033278=IBA, GO:0016324=IEA, GO:0030182=ISS, GO:0043025=IBA, GO:0060070=IDA, GO:0001942=IEA, GO:0001944=IBA, GO:0042813=IC, GO:0048786=IBA, GO:0042472=IBA, GO:0004930=IEA, GO:0001843=IBA, GO:0045177=IBA, GO:0032589=IBA, GO:0030165=IPI, GO:0036342=IEA, GO:0021754=IBA, GO:0016021=IEA, GO:0001764=IEA} G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger, canonical Wnt receptor signaling pathway, cell proliferation in midbrain, commissural neuron axon guidance, establishment of planar polarity, facial nucleus development, gonad development, hair follicle development, inner ear morphogenesis, neural tube closure, neuron differentiation, neuron migration, post-anal tail morphogenesis, vasculature development apical part of cell, apical plasma membrane, axon, cytoplasm, dendrite, integral to membrane, neuron projection membrane, neuronal cell body, plasma membrane, presynaptic active zone G-protein coupled receptor activity, PDZ domain binding, Wnt-activated receptor activity, Wnt-protein binding, protein binding Human FZD4 BHF-UCL UniProtKB {GO:0005515=PMID:20802536, GO:0017147=GO_REF:0000033, GO:0030947=GO_REF:0000033, GO:0005886=PMID:14688793, GO:0071300=GO_REF:0000024, GO:0007605=GO_REF:0000019, GO:0010812=PMID:18156211, GO:0042701=GO_REF:0000033, GO:0061299=PMID:15024691, GO:0009790=GO_REF:0000033, GO:0042995=GO_REF:0000033, GO:0042803=PMID:14688793, GO:0007223=PMID:12172548, GO:0051091=PMID:14688793, GO:0005737=GO_REF:0000033, GO:0005911=GO_REF:0000019, GO:0030182=GO_REF:0000024, GO:0034446=GO_REF:0000033, GO:0043507=GO_REF:0000019, GO:0016055=PMID:14688793, GO:0060070=PMID:15035989, GO:0031625=PMID:22575959, GO:0042813=PMID:17955262, GO:0046982=PMID:14688793, GO:0009986=PMID:19643732, GO:0004930=GO_REF:0000037, GO:0031987=GO_REF:0000019, GO:0035426=GO_REF:0000019, GO:0030165=PMID:20802536, GO:0019955=PMID:17955262, GO:0061304=GO_REF:0000019, GO:0007420=GO_REF:0000033, GO:0005887=PMID:17955262, GO:0045893=PMID:17955262, GO:0001570=GO_REF:0000033, GO:0061301=GO_REF:0000019} Q9ULV1 Frizzled-4 protein 20100806 {GO:0005515=IPI, GO:0017147=IBA, GO:0030947=IBA, GO:0005886=IDA, GO:0071300=ISS, GO:0007605=IEA, GO:0010812=IMP, GO:0042701=IBA, GO:0061299=IMP, GO:0009790=IBA, GO:0042995=IBA, GO:0042803=IPI, GO:0007223=IDA, GO:0051091=IDA, GO:0005737=IBA, GO:0005911=IEA, GO:0030182=ISS, GO:0034446=IBA, GO:0043507=IEA, GO:0016055=IDA, GO:0060070=IDA, GO:0031625=IPI, GO:0042813=IDA, GO:0046982=IPI, GO:0009986=IDA, GO:0004930=IEA, GO:0031987=IEA, GO:0035426=IEA, GO:0030165=IDA, GO:0019955=IPI, GO:0061304=IEA, GO:0007420=IBA, GO:0005887=IC, GO:0045893=IDA, GO:0001570=IBA, GO:0061301=IEA} Wnt receptor signaling pathway, Wnt receptor signaling pathway, calcium modulating pathway, brain development, canonical Wnt receptor signaling pathway, cellular response to retinoic acid, cerebellum vasculature morphogenesis, embryo development, extracellular matrix-cell signaling, locomotion involved in locomotory behavior, negative regulation of cell-substrate adhesion, neuron differentiation, positive regulation of JUN kinase activity, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription, DNA-dependent, progesterone secretion, regulation of vascular endothelial growth factor receptor signaling pathway, retina vasculature morphogenesis in camera-type eye, retinal blood vessel morphogenesis, sensory perception of sound, substrate adhesion-dependent cell spreading, vasculogenesis cell projection, cell surface, cell-cell junction, cytoplasm, integral to plasma membrane, plasma membrane G-protein coupled receptor activity, PDZ domain binding, Wnt-activated receptor activity, Wnt-protein binding, cytokine binding, protein binding, protein heterodimerization activity, protein homodimerization activity, ubiquitin protein ligase binding Human FZD5 BHF-UCL UniProtKB {GO:0008406=GO_REF:0000033, GO:0005515=PMID:18838381, GO:0017147=PMID:12490564, GO:0048471=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0005886=Reactome:REACT_21306, GO:0007409=GO_REF:0000033, GO:0042995=GO_REF:0000033, GO:0044332=PMID:11029007, GO:0005737=GO_REF:0000033, GO:0031076=GO_REF:0000033, GO:0000578=PMID:12121999, GO:0045944=PMID:10906785, GO:0030182=GO_REF:0000024, GO:0060716=GO_REF:0000033, GO:0048469=GO_REF:0000019, GO:0043507=GO_REF:0000019, GO:0008595=PMID:9054360, GO:0060070=PMID:12121999, GO:0071219=PMID:16601243, GO:0031625=PMID:22575959, GO:0032729=PMID:16601243, GO:0042813=PMID:9054360, GO:0033077=GO_REF:0000033, GO:0009986=PMID:19643732, GO:0019901=PMID:19643732, GO:0004930=GO_REF:0000037, GO:0006915=GO_REF:0000033, GO:0060561=GO_REF:0000019, GO:0001525=GO_REF:0000033, GO:0030165=GO_REF:0000033, GO:0031077=GO_REF:0000033, GO:0000139=GO_REF:0000039, GO:0007420=GO_REF:0000033, GO:0016021=GO_REF:0000037, GO:0060061=PMID:9054360} Q13467 Frizzled-5 protein 20110204 {GO:0008406=IBA, GO:0005515=IPI, GO:0017147=IPI, GO:0048471=IEA, GO:0008285=IEA, GO:0005886=TAS, GO:0007409=IBA, GO:0042995=IBA, GO:0044332=IDA, GO:0005737=IBA, GO:0031076=IBA, GO:0000578=IDA, GO:0045944=IGI, GO:0030182=ISS, GO:0060716=IBA, GO:0048469=IEA, GO:0043507=IEA, GO:0008595=IDA, GO:0060070=IDA, GO:0071219=IDA, GO:0031625=IPI, GO:0032729=IMP, GO:0042813=IC, GO:0033077=IBA, GO:0009986=IDA, GO:0019901=IPI, GO:0004930=IEA, GO:0006915=IBA, GO:0060561=IEA, GO:0001525=IBA, GO:0030165=IBA, GO:0031077=IBA, GO:0000139=IEA, GO:0007420=IBA, GO:0016021=IEA, GO:0060061=IDA} Spemann organizer formation, T cell differentiation in thymus, Wnt receptor signaling pathway involved in dorsal/ventral axis specification, angiogenesis, anterior/posterior axis specification, embryo, apoptotic process, apoptotic process involved in morphogenesis, axonogenesis, brain development, canonical Wnt receptor signaling pathway, cell maturation, cellular response to molecule of bacterial origin, embryonic axis specification, embryonic camera-type eye development, gonad development, labyrinthine layer blood vessel development, negative regulation of cell proliferation, neuron differentiation, positive regulation of JUN kinase activity, positive regulation of interferon-gamma production, positive regulation of transcription from RNA polymerase II promoter, post-embryonic camera-type eye development Golgi membrane, cell projection, cell surface, cytoplasm, integral to membrane, perinuclear region of cytoplasm, plasma membrane G-protein coupled receptor activity, PDZ domain binding, Wnt-activated receptor activity, Wnt-protein binding, protein binding, protein kinase binding, ubiquitin protein ligase binding Human FZD6 HPA UniProtKB {GO:0001736=GO_REF:0000033, GO:0008406=GO_REF:0000033, GO:0005515=PMID:10347172, GO:0017147=PMID:15265686, GO:0005886=GO_REF:0000052, GO:0007199=GO_REF:0000033, GO:0007409=GO_REF:0000033, GO:0043433=PMID:14747478, GO:0005737=GO_REF:0000033, GO:0033278=GO_REF:0000033, GO:0016055=GO_REF:0000038, GO:0090090=PMID:14747478, GO:0001942=GO_REF:0000019, GO:0060071=GO_REF:0000019, GO:0031625=PMID:22575959, GO:0042813=PMID:10347172, GO:0042472=GO_REF:0000033, GO:0004930=GO_REF:0000037, GO:0001843=GO_REF:0000033, GO:0030168=GO_REF:0000019, GO:0045177=GO_REF:0000033, GO:0007275=GO_REF:0000038, GO:0001525=GO_REF:0000033, GO:0030165=GO_REF:0000033, GO:0032589=GO_REF:0000033, GO:0016327=GO_REF:0000033, GO:0005887=PMID:15265686, GO:0016021=GO_REF:0000038, GO:0035567=PMID:14747478} O60353 Frizzled-6 protein 20090616 {GO:0001736=IBA, GO:0008406=IBA, GO:0005515=IPI, GO:0017147=ISS, GO:0005886=IDA, GO:0007199=IBA, GO:0007409=IBA, GO:0043433=IDA, GO:0005737=IBA, GO:0033278=IBA, GO:0016055=IEA, GO:0090090=IMP, GO:0001942=IEA, GO:0060071=IEA, GO:0031625=IPI, GO:0042813=IDA, GO:0042472=IBA, GO:0004930=IEA, GO:0001843=IBA, GO:0030168=IEA, GO:0045177=IBA, GO:0007275=IEA, GO:0001525=IBA, GO:0030165=IBA, GO:0032589=IBA, GO:0016327=IBA, GO:0005887=ISS, GO:0016021=IEA, GO:0035567=IDA} G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger, Wnt receptor signaling pathway, Wnt receptor signaling pathway, planar cell polarity pathway, angiogenesis, axonogenesis, cell proliferation in midbrain, establishment of planar polarity, gonad development, hair follicle development, inner ear morphogenesis, multicellular organismal development, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of sequence-specific DNA binding transcription factor activity, neural tube closure, non-canonical Wnt receptor signaling pathway, platelet activation apical part of cell, apicolateral plasma membrane, cytoplasm, integral to membrane, integral to plasma membrane, neuron projection membrane, plasma membrane G-protein coupled receptor activity, PDZ domain binding, Wnt-activated receptor activity, Wnt-protein binding, protein binding, ubiquitin protein ligase binding Human FZD7 BHF-UCL UniProtKB {GO:0008406=GO_REF:0000033, GO:0048103=GO_REF:0000019, GO:0017147=PMID:18313787, GO:0005886=PMID:18256285, GO:0071300=GO_REF:0000024, GO:0038031=PMID:19773752, GO:0007199=GO_REF:0000033, GO:0010812=PMID:18156211, GO:0046330=PMID:18256285, GO:0007409=GO_REF:0000033, GO:0042666=PMID:18681827, GO:0007223=GO_REF:0000033, GO:0035412=PMID:9707618, GO:0005737=GO_REF:0000033, GO:0030182=GO_REF:0000024, GO:0034446=GO_REF:0000019, GO:0014834=GO_REF:0000019, GO:0060070=PMID:19773752, GO:0001944=GO_REF:0000033, GO:0042813=GO_REF:0000033, GO:0060054=PMID:18313787, GO:0006355=PMID:18681827, GO:0033077=GO_REF:0000019, GO:0004930=GO_REF:0000037, GO:0060231=PMID:17016432, GO:0045177=GO_REF:0000033, GO:0032589=GO_REF:0000033, GO:0030165=PMID:18256285, GO:0007420=GO_REF:0000033, GO:0019827=PMID:18681827, GO:0016021=PMID:9707618, GO:0045893=PMID:19773752, GO:0042327=PMID:18256285} O75084 Frizzled-7 protein 20100806 {GO:0008406=IBA, GO:0048103=IEA, GO:0017147=IPI, GO:0005886=IDA, GO:0071300=ISS, GO:0038031=IMP, GO:0007199=IBA, GO:0010812=IMP, GO:0046330=IC, GO:0007409=IBA, GO:0042666=IMP, GO:0007223=IBA, GO:0035412=IMP, GO:0005737=IBA, GO:0030182=ISS, GO:0034446=IEA, GO:0014834=IEA, GO:0060070=IMP, GO:0001944=IBA, GO:0042813=IBA, GO:0060054=IMP, GO:0006355=IMP, GO:0033077=IEA, GO:0004930=IEA, GO:0060231=IMP, GO:0045177=IBA, GO:0032589=IBA, GO:0030165=IPI, GO:0007420=IBA, GO:0019827=IMP, GO:0016021=TAS, GO:0045893=IMP, GO:0042327=IDA} G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger, T cell differentiation in thymus, Wnt receptor signaling pathway, calcium modulating pathway, axonogenesis, brain development, canonical Wnt receptor signaling pathway, cellular response to retinoic acid, gonad development, mesenchymal to epithelial transition, negative regulation of cell-substrate adhesion, negative regulation of ectodermal cell fate specification, neuron differentiation, non-canonical Wnt receptor signaling pathway via JNK cascade, positive regulation of JNK cascade, positive regulation of epithelial cell proliferation involved in wound healing, positive regulation of phosphorylation, positive regulation of transcription, DNA-dependent, regulation of catenin import into nucleus, regulation of transcription, DNA-dependent, satellite cell maintenance involved in skeletal muscle regeneration, somatic stem cell division, stem cell maintenance, substrate adhesion-dependent cell spreading, vasculature development apical part of cell, cytoplasm, integral to membrane, neuron projection membrane, plasma membrane G-protein coupled receptor activity, PDZ domain binding, Wnt-activated receptor activity, Wnt-protein binding Human FZD8 BHF-UCL UniProtKB {GO:0005515=PMID:22682250, GO:0042813=PMID:11295046, GO:0008406=GO_REF:0000033, GO:0017147=GO_REF:0000033, GO:0033077=GO_REF:0000033, GO:0005794=GO_REF:0000039, GO:0005886=GO_REF:0000033, GO:0004930=GO_REF:0000037, GO:0005102=GO_REF:0000019, GO:0042995=GO_REF:0000033, GO:0000122=GO_REF:0000019, GO:0007409=GO_REF:0000033, GO:0009790=GO_REF:0000033, GO:0030165=PMID:18256285, GO:0005737=GO_REF:0000033, GO:0007420=GO_REF:0000033, GO:0030182=GO_REF:0000024, GO:0045944=GO_REF:0000019, GO:0016021=PMID:11295046, GO:0043507=GO_REF:0000019, GO:0060070=GO_REF:0000033, GO:0031625=PMID:22575959, GO:0001944=GO_REF:0000033} Q9H461 Frizzled-8 protein 20100810 {GO:0005515=IPI, GO:0042813=TAS, GO:0008406=IBA, GO:0017147=IBA, GO:0033077=IBA, GO:0005794=IEA, GO:0005886=IBA, GO:0004930=IEA, GO:0005102=IEA, GO:0042995=IBA, GO:0000122=IEA, GO:0007409=IBA, GO:0009790=IBA, GO:0030165=IPI, GO:0005737=IBA, GO:0007420=IBA, GO:0030182=ISS, GO:0045944=IEA, GO:0016021=TAS, GO:0043507=IEA, GO:0060070=IBA, GO:0031625=IPI, GO:0001944=IBA} T cell differentiation in thymus, axonogenesis, brain development, canonical Wnt receptor signaling pathway, embryo development, gonad development, negative regulation of transcription from RNA polymerase II promoter, neuron differentiation, positive regulation of JUN kinase activity, positive regulation of transcription from RNA polymerase II promoter, vasculature development Golgi apparatus, cell projection, cytoplasm, integral to membrane, plasma membrane G-protein coupled receptor activity, PDZ domain binding, Wnt-activated receptor activity, Wnt-protein binding, protein binding, receptor binding, ubiquitin protein ligase binding Human UniProtKB:O00560 FZD9 BHF-UCL UniProtKB {GO:0008406=GO_REF:0000033, GO:0042813=GO_REF:0000033, GO:0017147=PMID:19038973, GO:0048471=GO_REF:0000033, GO:0046982=PMID:14688793, GO:0009986=PMID:20458727, GO:0005886=PMID:19038973, GO:0004930=GO_REF:0000037, GO:0031527=GO_REF:0000033, GO:0009790=GO_REF:0000033, GO:0030165=GO_REF:0000033, GO:0042803=PMID:14688793, GO:0007399=PMID:9147651, GO:0007405=GO_REF:0000033, GO:0005737=PMID:19038973, GO:0007420=GO_REF:0000033, GO:0030183=GO_REF:0000033, GO:0007611=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0060070=GO_REF:0000033, GO:0001944=GO_REF:0000033} O00144 Frizzled-9 protein 20100818 {GO:0008406=IBA, GO:0042813=IBA, GO:0017147=IPI, GO:0048471=IBA, GO:0046982=IPI, GO:0009986=IDA, GO:0005886=IDA, GO:0004930=IEA, GO:0031527=IBA, GO:0009790=IBA, GO:0030165=IBA, GO:0042803=IPI, GO:0007399=TAS, GO:0007405=IBA, GO:0005737=IDA, GO:0007420=IBA, GO:0030183=IBA, GO:0007611=IEA, GO:0016021=IEA, GO:0060070=IBA, GO:0001944=IBA} B cell differentiation, brain development, canonical Wnt receptor signaling pathway, embryo development, gonad development, learning or memory, nervous system development, neuroblast proliferation, vasculature development cell surface, cytoplasm, filopodium membrane, integral to membrane, perinuclear region of cytoplasm, plasma membrane G-protein coupled receptor activity, PDZ domain binding, Wnt-activated receptor activity, Wnt-protein binding, protein heterodimerization activity, protein homodimerization activity Human FZR1 HPA UniProtKB {GO:0005515=PMID:22770219, GO:0031965=GO_REF:0000052, GO:0008284=GO_REF:0000019, GO:0045732=PMID:11459825, GO:0070306=GO_REF:0000019, GO:0031572=PMID:18662541, GO:0005730=GO_REF:0000052, GO:0051437=Reactome:REACT_6821, GO:0090344=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0051436=Reactome:REACT_6785, GO:0031145=Reactome:REACT_6828, GO:0051439=Reactome:REACT_6867, GO:0005829=Reactome:REACT_9035, GO:0051488=PMID:11459826, GO:0000084=Reactome:REACT_899, GO:0040020=GO_REF:0000019, GO:0007067=GO_REF:0000037, GO:0006281=GO_REF:0000037, GO:0070979=PMID:21596315, GO:0005680=PMID:11459825, GO:0005654=Reactome:REACT_9051, GO:0000278=Reactome:REACT_152, GO:0051301=GO_REF:0000037} Q9UM11 Fizzy-related protein homolog protein 20120912 {GO:0005515=IPI, GO:0031965=IDA, GO:0008284=IEA, GO:0045732=IGI, GO:0070306=IEA, GO:0031572=IDA, GO:0005730=IDA, GO:0051437=TAS, GO:0090344=IEA, GO:0005634=IDA, GO:0051436=TAS, GO:0031145=TAS, GO:0051439=TAS, GO:0005829=TAS, GO:0051488=IDA, GO:0000084=TAS, GO:0040020=IEA, GO:0007067=IEA, GO:0006281=IEA, GO:0070979=TAS, GO:0005680=IDA, GO:0005654=TAS, GO:0000278=TAS, GO:0051301=IEA} DNA repair, G2 DNA damage checkpoint, S phase of mitotic cell cycle, activation of anaphase-promoting complex activity, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell division, lens fiber cell differentiation, mitosis, mitotic cell cycle, negative regulation of cell aging, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of cell proliferation, positive regulation of protein catabolic process, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K11-linked ubiquitination, regulation of meiosis, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle anaphase-promoting complex, cytosol, nuclear membrane, nucleolus, nucleoplasm, nucleus protein binding Human G0S2 Reactome UniProtKB {GO:0005811=Reactome:REACT_115967, GO:0005515=PMID:19706769, GO:0005739=PMID:19706769, GO:0003674=GO_REF:0000015, GO:0043065=PMID:19706769, GO:0006915=PMID:19706769, GO:0044281=Reactome:REACT_111217, GO:0044255=Reactome:REACT_22279} P27469 G0/G1 switch protein 2 protein 20130301 {GO:0005811=TAS, GO:0005515=IPI, GO:0005739=IDA, GO:0003674=ND, GO:0043065=IDA, GO:0006915=IDA, GO:0044281=TAS, GO:0044255=TAS} apoptotic process, cellular lipid metabolic process, positive regulation of apoptotic process, small molecule metabolic process lipid particle, mitochondrion molecular_function, protein binding Human G2E3 HPA UniProtKB {GO:0000209=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0043066=GO_REF:0000019, GO:0004842=GO_REF:0000019, GO:0005794=GO_REF:0000052, GO:0001824=GO_REF:0000019, GO:0005730=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0043231=GO_REF:0000052} Q7L622 G2/M phase-specific E3 ubiquitin-protein ligase protein 20101115 {GO:0000209=IEA, GO:0005737=IDA, GO:0043066=IEA, GO:0004842=IEA, GO:0005794=IDA, GO:0001824=IEA, GO:0005730=IEA, GO:0006915=IEA, GO:0008270=IEA, GO:0043231=IDA} apoptotic process, blastocyst development, negative regulation of apoptotic process, protein polyubiquitination Golgi apparatus, cytoplasm, intracellular membrane-bounded organelle, nucleolus ubiquitin-protein ligase activity, zinc ion binding Human G3BP1 HPA UniProtKB {GO:0005515=PMID:23209657, GO:0005886=GO_REF:0000039, GO:0010494=GO_REF:0000019, GO:0007265=PMID:8649363, GO:0005634=GO_REF:0000039, GO:0003729=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0005829=GO_REF:0000039, GO:0004004=PMID:9889278, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0004003=PMID:9889278, GO:0004519=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0006810=GO_REF:0000037, GO:0090090=GO_REF:0000019} Q13283 Ras GTPase-activating protein-binding protein 1 protein 20080205 {GO:0005515=IPI, GO:0005886=IEA, GO:0010494=IEA, GO:0007265=TAS, GO:0005634=IEA, GO:0003729=IEA, GO:0003677=IEA, GO:0005524=IEA, GO:0005829=IEA, GO:0004004=TAS, GO:0005622=IEA, GO:0005737=IDA, GO:0004003=TAS, GO:0004519=IEA, GO:0000166=IEA, GO:0006810=IEA, GO:0090090=IEA} Ras protein signal transduction, negative regulation of canonical Wnt receptor signaling pathway, transport cytoplasm, cytoplasmic stress granule, cytosol, intracellular, nucleus, plasma membrane ATP binding, ATP-dependent DNA helicase activity, ATP-dependent RNA helicase activity, DNA binding, endonuclease activity, mRNA binding, nucleotide binding, protein binding Human G3BP2 HPA UniProtKB {GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0005737=GO_REF:0000052, GO:0000166=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0003723=GO_REF:0000029, GO:0007253=PMID:10969074, GO:0006810=GO_REF:0000002, GO:0030159=PMID:10969074, GO:0007265=PMID:9575347, GO:0051028=GO_REF:0000037, GO:0005829=Reactome:REACT_9982} Q9UN86 Ras GTPase-activating protein-binding protein 2 protein 20100326 {GO:0005622=IEA, GO:0051056=TAS, GO:0005737=IDA, GO:0000166=IEA, GO:0007264=TAS, GO:0003723=NAS, GO:0007253=NAS, GO:0006810=IEA, GO:0030159=NAS, GO:0007265=NAS, GO:0051028=IEA, GO:0005829=TAS} Ras protein signal transduction, cytoplasmic sequestering of NF-kappaB, mRNA transport, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction, transport cytoplasm, cytosol, intracellular RNA binding, nucleotide binding, receptor signaling complex scaffold activity Human G6PC Reactome UniProtKB {GO:0010468=GO_REF:0000019, GO:0006094=PMID:8211187, GO:0015760=GO_REF:0000019, GO:0030176=PMID:10318794, GO:0044281=Reactome:REACT_111217, GO:0046415=GO_REF:0000019, GO:0003824=GO_REF:0000002, GO:0008645=Reactome:REACT_9441, GO:0015758=Reactome:REACT_212, GO:0035264=GO_REF:0000019, GO:0016773=GO_REF:0000019, GO:0051156=GO_REF:0000019, GO:0008202=GO_REF:0000019, GO:0042632=GO_REF:0000019, GO:0005975=Reactome:REACT_474, GO:0005977=PMID:8211187, GO:0042593=PMID:8211187, GO:0055085=Reactome:REACT_19118, GO:0016020=GO_REF:0000002, GO:0042301=PMID:12093795, GO:0004346=PMID:15661744, GO:0005789=Reactome:REACT_1682, GO:0006641=GO_REF:0000019, GO:0016021=PMID:10318794, GO:0005980=GO_REF:0000019} P35575 Glucose-6-phosphatase protein 20130301 {GO:0010468=IEA, GO:0006094=IMP, GO:0015760=IEA, GO:0030176=TAS, GO:0044281=TAS, GO:0046415=IEA, GO:0003824=IEA, GO:0008645=TAS, GO:0015758=TAS, GO:0035264=IEA, GO:0016773=IEA, GO:0051156=IEA, GO:0008202=IEA, GO:0042632=IEA, GO:0005975=TAS, GO:0005977=TAS, GO:0042593=IMP, GO:0055085=TAS, GO:0016020=IEA, GO:0042301=IMP, GO:0004346=IDA, GO:0005789=TAS, GO:0006641=IEA, GO:0016021=IDA, GO:0005980=IEA} carbohydrate metabolic process, cholesterol homeostasis, gluconeogenesis, glucose 6-phosphate metabolic process, glucose homeostasis, glucose transport, glucose-6-phosphate transport, glycogen catabolic process, glycogen metabolic process, hexose transport, multicellular organism growth, regulation of gene expression, small molecule metabolic process, steroid metabolic process, transmembrane transport, triglyceride metabolic process, urate metabolic process endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane, integral to membrane, membrane catalytic activity, glucose-6-phosphatase activity, phosphate ion binding, phosphotransferase activity, alcohol group as acceptor Human G6PD HPA UniProtKB {GO:0050661=PMID:15858258, GO:0006629=PMID:17361089, GO:0014070=GO_REF:0000019, GO:0006695=PMID:12027950, GO:0045471=GO_REF:0000019, GO:0010734=PMID:17516514, GO:0006749=PMID:17516514, GO:0005634=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0006098=PMID:2297768, GO:0001816=PMID:17361089, GO:0032094=GO_REF:0000019, GO:0005536=PMID:5643703, GO:0042803=PMID:15858258, GO:0043231=GO_REF:0000052, GO:0005829=PMID:743300, GO:0005737=GO_REF:0000052, GO:0043249=PMID:5643703, GO:0051156=PMID:5643703, GO:0005813=GO_REF:0000052, GO:0005975=Reactome:REACT_474, GO:0009051=PMID:2420826, GO:0046390=PMID:2420826, GO:0019322=PMID:5643703, GO:0006740=PMID:17516514, GO:0004345=PMID:5643703, GO:0009898=PMID:743300, GO:0034599=PMID:17516514, GO:0055114=PMID:2420826} P11413 Glucose-6-phosphate 1-dehydrogenase protein 20101115 {GO:0050661=IDA, GO:0006629=TAS, GO:0014070=IEA, GO:0006695=IMP, GO:0045471=IEA, GO:0010734=IMP, GO:0006749=IMP, GO:0005634=IEA, GO:0044281=TAS, GO:0006098=IDA, GO:0001816=IMP, GO:0032094=IEA, GO:0005536=IMP, GO:0042803=IPI, GO:0043231=IDA, GO:0005829=IDA, GO:0005737=IDA, GO:0043249=IMP, GO:0051156=IMP, GO:0005813=IDA, GO:0005975=TAS, GO:0009051=IMP, GO:0046390=IMP, GO:0019322=IDA, GO:0006740=IMP, GO:0004345=IMP, GO:0009898=IDA, GO:0034599=IMP, GO:0055114=IMP} NADPH regeneration, carbohydrate metabolic process, cellular response to oxidative stress, cholesterol biosynthetic process, cytokine production, erythrocyte maturation, glucose 6-phosphate metabolic process, glutathione metabolic process, lipid metabolic process, negative regulation of protein glutathionylation, oxidation-reduction process, pentose biosynthetic process, pentose-phosphate shunt, pentose-phosphate shunt, oxidative branch, response to ethanol, response to food, response to organic cyclic compound, ribose phosphate biosynthetic process, small molecule metabolic process centrosome, cytoplasm, cytosol, internal side of plasma membrane, intracellular membrane-bounded organelle, nucleus NADP binding, glucose binding, glucose-6-phosphate dehydrogenase activity, protein homodimerization activity Human GAA BHF-UCL UniProtKB {GO:0055010=PMID:10931430, GO:0005765=GO_REF:0000039, GO:0005764=PMID:9505277, GO:0060048=PMID:10931430, GO:0004553=GO_REF:0000002, GO:0046716=GO_REF:0000019, GO:0002086=PMID:16917947, GO:0050884=GO_REF:0000019, GO:0050885=GO_REF:0000019, GO:0009888=GO_REF:0000019, GO:0006006=PMID:9505277, GO:0007626=GO_REF:0000019, GO:0005975=GO_REF:0000002, GO:0000023=PMID:9505277, GO:0003007=GO_REF:0000019, GO:0032450=GO_REF:0000003, GO:0007517=PMID:7717400, GO:0002026=GO_REF:0000019, GO:0030246=GO_REF:0000002, GO:0005985=PMID:9505277, GO:0043181=PMID:10931430, GO:0007040=PMID:7717400, GO:0043587=PMID:10931430, GO:0005980=PMID:9505277, GO:0004558=PMID:9505277} P10253 Lysosomal alpha-glucosidase protein 20071109 {GO:0055010=IMP, GO:0005765=IEA, GO:0005764=IDA, GO:0060048=IMP, GO:0004553=IEA, GO:0046716=IEA, GO:0002086=IMP, GO:0050884=IEA, GO:0050885=IEA, GO:0009888=IEA, GO:0006006=IC, GO:0007626=IEA, GO:0005975=IEA, GO:0000023=IC, GO:0003007=IEA, GO:0032450=IEA, GO:0007517=IMP, GO:0002026=IEA, GO:0030246=IEA, GO:0005985=IC, GO:0043181=IMP, GO:0007040=IMP, GO:0043587=IMP, GO:0005980=IDA, GO:0004558=IDA} carbohydrate metabolic process, cardiac muscle contraction, diaphragm contraction, glucose metabolic process, glycogen catabolic process, heart morphogenesis, locomotory behavior, lysosome organization, maltose metabolic process, muscle cell homeostasis, muscle organ development, neuromuscular process controlling balance, neuromuscular process controlling posture, regulation of the force of heart contraction, sucrose metabolic process, tissue development, tongue morphogenesis, vacuolar sequestering, ventricular cardiac muscle tissue morphogenesis lysosomal membrane, lysosome alpha-glucosidase activity, carbohydrate binding, hydrolase activity, hydrolyzing O-glycosyl compounds, maltose alpha-glucosidase activity Human GAB1 IntAct UniProtKB {GO:0005515=PMID:9658397, GO:0008286=Reactome:REACT_498, GO:0030334=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0060711=GO_REF:0000019, GO:0008283=PMID:8596638, GO:0048015=Reactome:REACT_12464, GO:0007257=GO_REF:0000019, GO:0005829=Reactome:REACT_147854, GO:0007507=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0007173=Reactome:REACT_9417, GO:0008544=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0005070=PMID:8596638, GO:0004871=GO_REF:0000019, GO:0048008=GO_REF:0000019, GO:0070102=GO_REF:0000019, GO:0006979=GO_REF:0000019} Q13480 GRB2-associated-binding protein 1 protein 20130415 {GO:0005515=IPI, GO:0008286=TAS, GO:0030334=IEA, GO:0048011=TAS, GO:0060711=IEA, GO:0008283=TAS, GO:0048015=TAS, GO:0007257=IEA, GO:0005829=TAS, GO:0007507=IEA, GO:0005737=IEA, GO:0005543=IEA, GO:0007173=TAS, GO:0008544=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:0005070=TAS, GO:0004871=IEA, GO:0048008=IEA, GO:0070102=IEA, GO:0006979=IEA} activation of JUN kinase activity, cell proliferation, epidermal growth factor receptor signaling pathway, epidermis development, fibroblast growth factor receptor signaling pathway, heart development, innate immune response, insulin receptor signaling pathway, interleukin-6-mediated signaling pathway, labyrinthine layer development, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, platelet-derived growth factor receptor signaling pathway, regulation of cell migration, response to oxidative stress cytoplasm, cytosol SH3/SH2 adaptor activity, phospholipid binding, protein binding, signal transducer activity Human UniProtKB:Q06124 GAB2 GOC UniProtKB {GO:0005515=PMID:21706016, GO:0008284=PMID:19172738, GO:0005886=PMID:19172738, GO:0048015=GO_REF:0000024, GO:0043325=GO_REF:0000024, GO:0030316=PMID:15750601, GO:0005547=GO_REF:0000024, GO:0043306=GO_REF:0000024, GO:0005829=Reactome:REACT_121343, GO:0005737=PMID:19172738, GO:0005543=GO_REF:0000002, GO:0005070=PMID:19641626, GO:0005068=PMID:19172738, GO:0007169=PMID:19172738} Q9UQC2 GRB2-associated-binding protein 2 protein 20130413 {GO:0005515=IPI, GO:0008284=IDA, GO:0005886=IDA, GO:0048015=ISS, GO:0043325=ISS, GO:0030316=IMP, GO:0005547=ISS, GO:0043306=ISS, GO:0005829=TAS, GO:0005737=IDA, GO:0005543=IEA, GO:0005070=RCA, GO:0005068=IDA, GO:0007169=IDA} osteoclast differentiation, phosphatidylinositol-mediated signaling, positive regulation of cell proliferation, positive regulation of mast cell degranulation, transmembrane receptor protein tyrosine kinase signaling pathway cytoplasm, cytosol, plasma membrane SH3/SH2 adaptor activity, phosphatidylinositol-3,4,5-trisphosphate binding, phosphatidylinositol-3,4-bisphosphate binding, phospholipid binding, protein binding, transmembrane receptor protein tyrosine kinase adaptor activity Human GAB3 InterPro UniProtKB {GO:0005543=GO_REF:0000002} Q8WWW8 GRB2-associated-binding protein 3 protein 20130413 {GO:0005543=IEA} phospholipid binding Human InterPro:IPR001849 GABARAP IntAct UniProtKB {GO:0005515=PMID:20562859, GO:0008017=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0005776=PMID:19056683, GO:0005794=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0005875=GO_REF:0000019, GO:0000421=PMID:15169837, GO:0005874=GO_REF:0000037, GO:0048487=PMID:9892355, GO:0006914=GO_REF:0000037, GO:0006915=PMID:15977068, GO:0000226=GO_REF:0000019, GO:0007268=PMID:9892355, GO:0006605=PMID:9892355, GO:0031410=GO_REF:0000037, GO:0050811=PMID:9892355, GO:0015031=GO_REF:0000019, GO:0015629=GO_REF:0000019, GO:0005764=GO_REF:0000019, GO:0044297=GO_REF:0000019, GO:0005790=GO_REF:0000019, GO:0000139=GO_REF:0000039} O95166 Gamma-aminobutyric acid receptor-associated protein protein 20130415 {GO:0005515=IPI, GO:0008017=IEA, GO:0048471=IEA, GO:0005776=IDA, GO:0005794=IEA, GO:0005886=IEA, GO:0005875=IEA, GO:0000421=IDA, GO:0005874=IEA, GO:0048487=IDA, GO:0006914=IEA, GO:0006915=IDA, GO:0000226=IEA, GO:0007268=TAS, GO:0006605=TAS, GO:0031410=IEA, GO:0050811=IPI, GO:0015031=IEA, GO:0015629=IEA, GO:0005764=IEA, GO:0044297=IEA, GO:0005790=IEA, GO:0000139=IEA} apoptotic process, autophagy, microtubule cytoskeleton organization, protein targeting, protein transport, synaptic transmission Golgi apparatus, Golgi membrane, actin cytoskeleton, autophagic vacuole, autophagic vacuole membrane, cell body, cytoplasmic vesicle, lysosome, microtubule, microtubule associated complex, perinuclear region of cytoplasm, plasma membrane, smooth endoplasmic reticulum GABA receptor binding, beta-tubulin binding, microtubule binding, protein binding Human UniProtKB:Q9Y4P1 GABARAPL1 IntAct UniProtKB {GO:0005622=GO_REF:0000054, GO:0005515=PMID:20562859, GO:0005776=PMID:15292400, GO:0005794=GO_REF:0000039, GO:0005783=GO_REF:0000039, GO:0005874=GO_REF:0000037, GO:0048487=GO_REF:0000024, GO:0006914=GO_REF:0000037, GO:0050811=GO_REF:0000024, GO:0030659=GO_REF:0000039} Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 protein 20130415 {GO:0005622=IDA, GO:0005515=IPI, GO:0005776=IDA, GO:0005794=IEA, GO:0005783=IEA, GO:0005874=IEA, GO:0048487=ISS, GO:0006914=IEA, GO:0050811=ISS, GO:0030659=IEA} autophagy Golgi apparatus, autophagic vacuole, cytoplasmic vesicle membrane, endoplasmic reticulum, intracellular, microtubule GABA receptor binding, beta-tubulin binding, protein binding Human UniProtKB:Q9Y4P1 GABARAPL2 BHF-UCL UniProtKB {GO:0005515=PMID:21669198, GO:0008017=PMID:11414770, GO:0005776=PMID:21669198, GO:0005794=PMID:11414770, GO:0000421=PMID:15169837, GO:0048487=GO_REF:0000024, GO:0006914=PMID:12507496, GO:0006891=PMID:10747018, GO:0031410=GO_REF:0000037, GO:0050811=PMID:11414770, GO:0032781=PMID:10747018, GO:0015031=GO_REF:0000037, GO:0005829=PMID:11414770, GO:0005622=GO_REF:0000054, GO:0005737=PMID:21669198, GO:0000139=PMID:21669198, GO:0000149=PMID:10747018, GO:0051117=PMID:10747018} P60520 Gamma-aminobutyric acid receptor-associated protein-like 2 protein 20130121 {GO:0005515=IPI, GO:0008017=NAS, GO:0005776=IDA, GO:0005794=ISS, GO:0000421=IDA, GO:0048487=ISS, GO:0006914=NAS, GO:0006891=ISS, GO:0031410=IEA, GO:0050811=NAS, GO:0032781=ISS, GO:0015031=IEA, GO:0005829=ISS, GO:0005622=IDA, GO:0005737=IDA, GO:0000139=IDA, GO:0000149=ISS, GO:0051117=ISS} autophagy, intra-Golgi vesicle-mediated transport, positive regulation of ATPase activity, protein transport Golgi apparatus, Golgi membrane, autophagic vacuole, autophagic vacuole membrane, cytoplasm, cytoplasmic vesicle, cytosol, intracellular ATPase binding, GABA receptor binding, SNARE binding, beta-tubulin binding, microtubule binding, protein binding Human GABBR1 IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25066, GO:0004965=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0007214=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0038037=GO_REF:0000019, GO:0007194=PMID:9069281, GO:0042734=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0005887=PMID:9753614, GO:0045211=GO_REF:0000039, GO:0016021=GO_REF:0000038} Q9UBS5 Gamma-aminobutyric acid type B receptor subunit 1 protein 20130415 {GO:0005515=IPI, GO:0030054=IEA, GO:0005886=TAS, GO:0004965=IEA, GO:0007268=TAS, GO:0007214=IEA, GO:0005576=IEA, GO:0038037=IEA, GO:0007194=TAS, GO:0042734=IEA, GO:0005737=IEA, GO:0005887=TAS, GO:0045211=IEA, GO:0016021=IEA} gamma-aminobutyric acid signaling pathway, negative regulation of adenylate cyclase activity, synaptic transmission G-protein coupled receptor dimeric complex, cell junction, cytoplasm, extracellular region, integral to membrane, integral to plasma membrane, plasma membrane, postsynaptic membrane, presynaptic membrane G-protein coupled GABA receptor activity, protein binding Human UniProtKB:P61244 GABBR2 Reactome UniProtKB {GO:0043005=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25066, GO:0007186=PMID:9872316, GO:0005887=PMID:10328880, GO:0045211=GO_REF:0000039, GO:0004965=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0007214=GO_REF:0000019, GO:0007194=PMID:10328880} O75899 Gamma-aminobutyric acid type B receptor subunit 2 protein 20101111 {GO:0043005=IEA, GO:0005737=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0045211=IEA, GO:0004965=IEA, GO:0007268=TAS, GO:0007214=IEA, GO:0007194=TAS} G-protein coupled receptor signaling pathway, gamma-aminobutyric acid signaling pathway, negative regulation of adenylate cyclase activity, synaptic transmission cell junction, cytoplasm, integral to plasma membrane, neuron projection, plasma membrane, postsynaptic membrane G-protein coupled GABA receptor activity Human GABPA BHF-UCL UniProtKB {GO:0005515=PMID:10675337, GO:0000790=PMID:22306510, GO:0003700=PMID:8441384, GO:0044212=PMID:9857059, GO:0046982=PMID:9857059, GO:0006366=PMID:8441384, GO:0003713=PMID:8441384, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000122=GO_REF:0000019, GO:0000978=PMID:22306510, GO:0001228=PMID:22306510, GO:0001701=GO_REF:0000019, GO:0003677=PMID:8441384, GO:0045944=PMID:22306510} Q06546 GA-binding protein alpha chain protein 20121109 {GO:0005515=IPI, GO:0000790=IDA, GO:0003700=TAS, GO:0044212=IDA, GO:0046982=IDA, GO:0006366=TAS, GO:0003713=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0000122=IEA, GO:0000978=IDA, GO:0001228=IDA, GO:0001701=IEA, GO:0003677=TAS, GO:0045944=IDA} in utero embryonic development, negative regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter nuclear chromatin, nucleolus, nucleus DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, protein binding, protein heterodimerization activity, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, transcription regulatory region DNA binding Human GABPB1 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0003700=PMID:8441384, GO:0006357=PMID:8441384, GO:0046982=PMID:9857059, GO:0044212=PMID:9857059, GO:0045944=PMID:9857059, GO:0005634=PMID:9857059, GO:0006351=GO_REF:0000037} Q06547 GA-binding protein subunit beta-1 protein 20130415 {GO:0005515=IPI, GO:0003700=TAS, GO:0006357=TAS, GO:0046982=IDA, GO:0044212=IDA, GO:0045944=IDA, GO:0005634=IDA, GO:0006351=IEA} positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus protein binding, protein heterodimerization activity, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding Human UniProtKB:Q96M61 GABPB2 MGI UniProtKB {GO:0046982=PMID:9857059, GO:0044212=PMID:9857059, GO:0045944=PMID:9857059, GO:0005634=PMID:9857059, GO:0042803=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q8TAK5 GA-binding protein subunit beta-2 protein 20100615 {GO:0046982=IDA, GO:0044212=IDA, GO:0045944=IDA, GO:0005634=IDA, GO:0042803=IEA, GO:0006351=IEA} positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus protein heterodimerization activity, protein homodimerization activity, transcription regulatory region DNA binding Human GABRA1 BHF-UCL UniProtKB {GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25130, GO:0004890=GO_REF:0000002, GO:0034707=GO_REF:0000037, GO:0016917=GO_REF:0000024, GO:0007268=Reactome:REACT_13685, GO:0007214=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000037, GO:0034220=Reactome:REACT_25387, GO:0005887=GO_REF:0000024, GO:0008144=GO_REF:0000024, GO:0045211=GO_REF:0000039, GO:0006810=PMID:2465923, GO:0016021=GO_REF:0000002, GO:0051932=GO_REF:0000024} P14867 Gamma-aminobutyric acid receptor subunit alpha-1 protein 20120314 {GO:0005230=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0004890=IEA, GO:0034707=IEA, GO:0016917=ISS, GO:0007268=TAS, GO:0007214=IEA, GO:0055085=TAS, GO:0005254=IEA, GO:0034220=TAS, GO:0005887=ISS, GO:0008144=ISS, GO:0045211=IEA, GO:0006810=TAS, GO:0016021=IEA, GO:0051932=ISS} gamma-aminobutyric acid signaling pathway, ion transmembrane transport, synaptic transmission, synaptic transmission, GABAergic, transmembrane transport, transport cell junction, chloride channel complex, integral to membrane, integral to plasma membrane, plasma membrane, postsynaptic membrane GABA receptor activity, GABA-A receptor activity, chloride channel activity, drug binding, extracellular ligand-gated ion channel activity Human UniProtKB:P62813 GABRA2 Reactome UniProtKB {GO:0006821=GO_REF:0000002, GO:0030424=GO_REF:0000019, GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25130, GO:0004890=GO_REF:0000002, GO:0034707=GO_REF:0000037, GO:0007268=Reactome:REACT_13685, GO:0007214=PMID:8391122, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000037, GO:0034220=Reactome:REACT_25387, GO:0030285=PMID:8391122, GO:0001505=PMID:8391122, GO:0045211=GO_REF:0000039, GO:0008503=PMID:8391122, GO:0006836=PMID:8391122, GO:0016021=GO_REF:0000002, GO:0006811=GO_REF:0000002} P47869 Gamma-aminobutyric acid receptor subunit alpha-2 protein 20130301 {GO:0006821=IEA, GO:0030424=IEA, GO:0005230=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0004890=IEA, GO:0034707=IEA, GO:0007268=TAS, GO:0007214=IMP, GO:0055085=TAS, GO:0005254=IEA, GO:0034220=TAS, GO:0030285=IDA, GO:0001505=IMP, GO:0045211=IEA, GO:0008503=IMP, GO:0006836=IMP, GO:0016021=IEA, GO:0006811=IEA} chloride transport, gamma-aminobutyric acid signaling pathway, ion transmembrane transport, ion transport, neurotransmitter transport, regulation of neurotransmitter levels, synaptic transmission, transmembrane transport axon, cell junction, chloride channel complex, integral to membrane, integral to synaptic vesicle membrane, plasma membrane, postsynaptic membrane GABA-A receptor activity, benzodiazepine receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity Human GABRA3 Reactome UniProtKB {GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25130, GO:0004890=GO_REF:0000002, GO:0034707=GO_REF:0000037, GO:0007268=Reactome:REACT_13685, GO:0007214=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000037, GO:0034220=Reactome:REACT_25387, GO:0005887=PMID:8391122, GO:0045211=GO_REF:0000039, GO:0006810=PMID:8391122, GO:0008503=PMID:8391122, GO:0016021=GO_REF:0000002} P34903 Gamma-aminobutyric acid receptor subunit alpha-3 protein 20130301 {GO:0005230=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0004890=IEA, GO:0034707=IEA, GO:0007268=TAS, GO:0007214=IEA, GO:0055085=TAS, GO:0005254=IEA, GO:0034220=TAS, GO:0005887=TAS, GO:0045211=IEA, GO:0006810=TAS, GO:0008503=TAS, GO:0016021=IEA} gamma-aminobutyric acid signaling pathway, ion transmembrane transport, synaptic transmission, transmembrane transport, transport cell junction, chloride channel complex, integral to membrane, integral to plasma membrane, plasma membrane, postsynaptic membrane GABA-A receptor activity, benzodiazepine receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity Human GABRA4 Reactome UniProtKB {GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25130, GO:0004890=GO_REF:0000002, GO:0034707=GO_REF:0000037, GO:0007268=Reactome:REACT_13685, GO:0007214=GO_REF:0000002, GO:0007417=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000037, GO:0034220=Reactome:REACT_25387, GO:0005887=PMID:8719416, GO:0045211=GO_REF:0000039, GO:0006810=PMID:8719416, GO:0008503=PMID:8719416, GO:2001023=GO_REF:0000019} P48169 Gamma-aminobutyric acid receptor subunit alpha-4 protein 20130301 {GO:0005230=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0004890=IEA, GO:0034707=IEA, GO:0007268=TAS, GO:0007214=IEA, GO:0007417=IEA, GO:0055085=TAS, GO:0005254=IEA, GO:0034220=TAS, GO:0005887=TAS, GO:0045211=IEA, GO:0006810=TAS, GO:0008503=TAS, GO:2001023=IEA} central nervous system development, gamma-aminobutyric acid signaling pathway, ion transmembrane transport, regulation of response to drug, synaptic transmission, transmembrane transport, transport cell junction, chloride channel complex, integral to plasma membrane, plasma membrane, postsynaptic membrane GABA-A receptor activity, benzodiazepine receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity Human GABRA5 Reactome UniProtKB {GO:0006821=GO_REF:0000002, GO:0005215=PMID:1321750, GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25130, GO:0007605=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0050811=GO_REF:0000019, GO:0005254=GO_REF:0000037, GO:0030425=GO_REF:0000019, GO:0034220=Reactome:REACT_25387, GO:0045211=GO_REF:0000039, GO:0006810=PMID:1321750, GO:0090102=GO_REF:0000019, GO:0001662=GO_REF:0000019, GO:0004872=PMID:1321750, GO:0008306=GO_REF:0000019, GO:0004890=GO_REF:0000019, GO:0034707=GO_REF:0000037, GO:0060119=GO_REF:0000019, GO:0007214=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0032809=GO_REF:0000019, GO:0043235=GO_REF:0000019, GO:0060384=GO_REF:0000019, GO:0007165=PMID:1321750, GO:0007420=GO_REF:0000019, GO:0005887=PMID:1321750, GO:0016021=GO_REF:0000002, GO:0005216=GO_REF:0000002} P31644 Gamma-aminobutyric acid receptor subunit alpha-5 protein 20130301 {GO:0006821=IEA, GO:0005215=TAS, GO:0005230=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0007605=IEA, GO:0007268=TAS, GO:0050811=IEA, GO:0005254=IEA, GO:0030425=IEA, GO:0034220=TAS, GO:0045211=IEA, GO:0006810=TAS, GO:0090102=IEA, GO:0001662=IEA, GO:0004872=TAS, GO:0008306=IEA, GO:0004890=IEA, GO:0034707=IEA, GO:0060119=IEA, GO:0007214=IEA, GO:0055085=TAS, GO:0032809=IEA, GO:0043235=IEA, GO:0060384=IEA, GO:0007165=TAS, GO:0007420=IEA, GO:0005887=TAS, GO:0016021=IEA, GO:0005216=IEA} associative learning, behavioral fear response, brain development, chloride transport, cochlea development, gamma-aminobutyric acid signaling pathway, inner ear receptor cell development, innervation, ion transmembrane transport, sensory perception of sound, signal transduction, synaptic transmission, transmembrane transport, transport cell junction, chloride channel complex, dendrite, integral to membrane, integral to plasma membrane, neuronal cell body membrane, plasma membrane, postsynaptic membrane, receptor complex GABA receptor binding, GABA-A receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity, ion channel activity, receptor activity, transporter activity Human GABRA6 Reactome UniProtKB {GO:0006821=GO_REF:0000002, GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25130, GO:0004890=GO_REF:0000002, GO:0034707=GO_REF:0000037, GO:0007268=Reactome:REACT_13685, GO:0007214=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000037, GO:0007165=PMID:8632757, GO:0034220=Reactome:REACT_25387, GO:0005887=PMID:8632757, GO:0045211=GO_REF:0000039, GO:0008503=PMID:8632757, GO:0006810=PMID:8632757, GO:0016021=GO_REF:0000002} Q16445 Gamma-aminobutyric acid receptor subunit alpha-6 protein 20130301 {GO:0006821=IEA, GO:0005230=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0004890=IEA, GO:0034707=IEA, GO:0007268=TAS, GO:0007214=IEA, GO:0055085=TAS, GO:0005254=IEA, GO:0007165=TAS, GO:0034220=TAS, GO:0005887=TAS, GO:0045211=IEA, GO:0008503=TAS, GO:0006810=TAS, GO:0016021=IEA} chloride transport, gamma-aminobutyric acid signaling pathway, ion transmembrane transport, signal transduction, synaptic transmission, transmembrane transport, transport cell junction, chloride channel complex, integral to membrane, integral to plasma membrane, plasma membrane, postsynaptic membrane GABA-A receptor activity, benzodiazepine receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity Human GABRB1 Reactome UniProtKB {GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25130, GO:0007268=Reactome:REACT_13685, GO:0042698=GO_REF:0000019, GO:0005635=GO_REF:0000019, GO:0050811=GO_REF:0000019, GO:0005254=GO_REF:0000037, GO:0030425=GO_REF:0000019, GO:0005253=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0034220=Reactome:REACT_25387, GO:0045211=GO_REF:0000039, GO:0006810=PMID:2465923, GO:0006811=GO_REF:0000002, GO:0004890=GO_REF:0000019, GO:0021954=GO_REF:0000019, GO:0034707=GO_REF:0000037, GO:0009636=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0043235=GO_REF:0000019, GO:0007165=PMID:2465923, GO:0005887=PMID:2465923, GO:0032570=GO_REF:0000019, GO:0016021=GO_REF:0000038} P18505 Gamma-aminobutyric acid receptor subunit beta-1 protein 20130301 {GO:0005230=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0007268=TAS, GO:0042698=IEA, GO:0005635=IEA, GO:0050811=IEA, GO:0005254=IEA, GO:0030425=IEA, GO:0005253=IEA, GO:0005737=IEA, GO:0034220=TAS, GO:0045211=IEA, GO:0006810=TAS, GO:0006811=IEA, GO:0004890=IEA, GO:0021954=IEA, GO:0034707=IEA, GO:0009636=IEA, GO:0055085=TAS, GO:0043235=IEA, GO:0007165=TAS, GO:0005887=TAS, GO:0032570=IEA, GO:0016021=IEA} central nervous system neuron development, ion transmembrane transport, ion transport, ovulation cycle, response to progesterone stimulus, response to toxic substance, signal transduction, synaptic transmission, transmembrane transport, transport cell junction, chloride channel complex, cytoplasm, dendrite, integral to membrane, integral to plasma membrane, nuclear envelope, plasma membrane, postsynaptic membrane, receptor complex GABA receptor binding, GABA-A receptor activity, anion channel activity, chloride channel activity, extracellular ligand-gated ion channel activity Human GABRB2 BHF-UCL UniProtKB {GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25130, GO:0004890=GO_REF:0000024, GO:0005237=GO_REF:0000019, GO:0007605=GO_REF:0000019, GO:0034707=GO_REF:0000037, GO:0007268=Reactome:REACT_13685, GO:0060119=GO_REF:0000019, GO:0007214=PMID:8264558, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000037, GO:0005829=GO_REF:0000019, GO:0060384=GO_REF:0000019, GO:0034220=Reactome:REACT_25387, GO:0005887=PMID:8264558, GO:0045211=GO_REF:0000039, GO:0006810=PMID:8264558, GO:0090102=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0051932=GO_REF:0000024} P47870 Gamma-aminobutyric acid receptor subunit beta-2 protein 20120314 {GO:0005230=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0004890=ISS, GO:0005237=IEA, GO:0007605=IEA, GO:0034707=IEA, GO:0007268=TAS, GO:0060119=IEA, GO:0007214=TAS, GO:0055085=TAS, GO:0005254=IEA, GO:0005829=IEA, GO:0060384=IEA, GO:0034220=TAS, GO:0005887=TAS, GO:0045211=IEA, GO:0006810=TAS, GO:0090102=IEA, GO:0016021=IEA, GO:0051932=ISS} cochlea development, gamma-aminobutyric acid signaling pathway, inner ear receptor cell development, innervation, ion transmembrane transport, sensory perception of sound, synaptic transmission, synaptic transmission, GABAergic, transmembrane transport, transport cell junction, chloride channel complex, cytosol, integral to membrane, integral to plasma membrane, plasma membrane, postsynaptic membrane GABA-A receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity, inhibitory extracellular ligand-gated ion channel activity Human UniProtKB:P63138 GABRB3 Reactome UniProtKB {GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25130, GO:0004890=GO_REF:0000002, GO:0007605=GO_REF:0000019, GO:0034707=GO_REF:0000037, GO:0007268=Reactome:REACT_13685, GO:0060119=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000037, GO:0060384=GO_REF:0000019, GO:0007165=PMID:1664410, GO:0034220=Reactome:REACT_25387, GO:0005887=PMID:1664410, GO:0045211=GO_REF:0000039, GO:0006810=PMID:1664410, GO:0090102=GO_REF:0000019, GO:0016021=GO_REF:0000002, GO:0006811=GO_REF:0000002} P28472 Gamma-aminobutyric acid receptor subunit beta-3 protein 20130301 {GO:0005230=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0004890=IEA, GO:0007605=IEA, GO:0034707=IEA, GO:0007268=TAS, GO:0060119=IEA, GO:0055085=TAS, GO:0005254=IEA, GO:0060384=IEA, GO:0007165=TAS, GO:0034220=TAS, GO:0005887=TAS, GO:0045211=IEA, GO:0006810=TAS, GO:0090102=IEA, GO:0016021=IEA, GO:0006811=IEA} cochlea development, inner ear receptor cell development, innervation, ion transmembrane transport, ion transport, sensory perception of sound, signal transduction, synaptic transmission, transmembrane transport, transport cell junction, chloride channel complex, integral to membrane, integral to plasma membrane, plasma membrane, postsynaptic membrane GABA-A receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity Human GABRD PINC UniProtKB {GO:0007165=PMID:2176788, GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005887=PMID:2176788, GO:0004890=GO_REF:0000019, GO:0045211=GO_REF:0000039, GO:0006810=PMID:2176788, GO:0034707=GO_REF:0000037, GO:0007268=GO_REF:0000019, GO:0005254=GO_REF:0000037} O14764 Gamma-aminobutyric acid receptor subunit delta protein 20030904 {GO:0007165=TAS, GO:0005230=IEA, GO:0030054=IEA, GO:0005887=TAS, GO:0004890=IEA, GO:0045211=IEA, GO:0006810=TAS, GO:0034707=IEA, GO:0007268=IEA, GO:0005254=IEA} signal transduction, synaptic transmission, transport cell junction, chloride channel complex, integral to plasma membrane, postsynaptic membrane GABA-A receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity Human GABRG1 UniProtKB UniProtKB {GO:0043235=GO_REF:0000019, GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0004890=GO_REF:0000019, GO:0045211=GO_REF:0000039, GO:0034707=GO_REF:0000037, GO:0007268=GO_REF:0000019, GO:0007214=GO_REF:0000002, GO:0050811=GO_REF:0000019, GO:0005254=GO_REF:0000037} Q8N1C3 Gamma-aminobutyric acid receptor subunit gamma-1 protein 20130413 {GO:0043235=IEA, GO:0005230=IEA, GO:0030054=IEA, GO:0005886=IEA, GO:0004890=IEA, GO:0045211=IEA, GO:0034707=IEA, GO:0007268=IEA, GO:0007214=IEA, GO:0050811=IEA, GO:0005254=IEA} gamma-aminobutyric acid signaling pathway, synaptic transmission cell junction, chloride channel complex, plasma membrane, postsynaptic membrane, receptor complex GABA receptor binding, GABA-A receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity Human UniProtKB-SubCell:SL-0219 GABRG2 BHF-UCL UniProtKB {GO:0005515=PMID:9892355, GO:0006821=GO_REF:0000002, GO:0030424=GO_REF:0000019, GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25130, GO:0004890=GO_REF:0000002, GO:0034707=GO_REF:0000037, GO:0007268=Reactome:REACT_13685, GO:0060077=GO_REF:0000019, GO:0007214=GO_REF:0000002, GO:0009791=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000037, GO:0005737=GO_REF:0000019, GO:0034220=Reactome:REACT_25387, GO:0032590=GO_REF:0000024, GO:0005887=PMID:2538761, GO:0045211=GO_REF:0000039, GO:0006810=PMID:2538761, GO:0008503=PMID:2538761, GO:0030534=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0051932=GO_REF:0000024} P18507 Gamma-aminobutyric acid receptor subunit gamma-2 protein 20120314 {GO:0005515=IPI, GO:0006821=IEA, GO:0030424=IEA, GO:0005230=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0004890=IEA, GO:0034707=IEA, GO:0007268=TAS, GO:0060077=IEA, GO:0007214=IEA, GO:0009791=IEA, GO:0055085=TAS, GO:0005254=IEA, GO:0005737=IEA, GO:0034220=TAS, GO:0032590=ISS, GO:0005887=TAS, GO:0045211=IEA, GO:0006810=TAS, GO:0008503=TAS, GO:0030534=IEA, GO:0016021=IEA, GO:0051932=ISS} adult behavior, chloride transport, gamma-aminobutyric acid signaling pathway, ion transmembrane transport, post-embryonic development, synaptic transmission, synaptic transmission, GABAergic, transmembrane transport, transport axon, cell junction, chloride channel complex, cytoplasm, dendrite membrane, inhibitory synapse, integral to membrane, integral to plasma membrane, plasma membrane, postsynaptic membrane GABA-A receptor activity, benzodiazepine receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity, protein binding Human UniProtKB:P18508 GABRG3 Reactome UniProtKB {GO:0006821=GO_REF:0000002, GO:0005230=GO_REF:0000029, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25130, GO:0004890=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0034707=GO_REF:0000037, GO:0007268=Reactome:REACT_13685, GO:0007214=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000019, GO:0034220=Reactome:REACT_25387, GO:0045211=GO_REF:0000039, GO:0016021=GO_REF:0000029} Q99928 Gamma-aminobutyric acid receptor subunit gamma-3 protein 20130301 {GO:0006821=IEA, GO:0005230=NAS, GO:0030054=IEA, GO:0005886=TAS, GO:0004890=IEA, GO:0042493=IEA, GO:0034707=IEA, GO:0007268=TAS, GO:0007214=IEA, GO:0055085=TAS, GO:0005254=IEA, GO:0034220=TAS, GO:0045211=IEA, GO:0016021=NAS} chloride transport, gamma-aminobutyric acid signaling pathway, ion transmembrane transport, response to drug, synaptic transmission, transmembrane transport cell junction, chloride channel complex, integral to membrane, plasma membrane, postsynaptic membrane GABA-A receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity Human GABRQ GOC UniProtKB {GO:0007165=PMID:10449790, GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005887=PMID:10449790, GO:0004890=GO_REF:0000002, GO:0045211=GO_REF:0000039, GO:0005326=PMID:10449790, GO:0006836=PMID:10449790, GO:0034707=GO_REF:0000037, GO:0005254=GO_REF:0000037, GO:0004888=PMID:10449790} Q9UN88 Gamma-aminobutyric acid receptor subunit theta protein 20130413 {GO:0007165=TAS, GO:0005230=IEA, GO:0030054=IEA, GO:0005887=TAS, GO:0004890=IEA, GO:0045211=IEA, GO:0005326=TAS, GO:0006836=TAS, GO:0034707=IEA, GO:0005254=IEA, GO:0004888=TAS} neurotransmitter transport, signal transduction cell junction, chloride channel complex, integral to plasma membrane, postsynaptic membrane GABA-A receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity, neurotransmitter transporter activity, transmembrane signaling receptor activity Human GABRR1 Reactome UniProtKB {GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25391, GO:0004890=GO_REF:0000002, GO:0034707=GO_REF:0000037, GO:0007268=Reactome:REACT_13685, GO:0007214=PMID:10779366, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000037, GO:0034220=Reactome:REACT_25387, GO:0005887=PMID:10779366, GO:0045211=GO_REF:0000039, GO:0006810=PMID:1849271, GO:0016021=GO_REF:0000038} P24046 Gamma-aminobutyric acid receptor subunit rho-1 protein 20130301 {GO:0005230=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0004890=IEA, GO:0034707=IEA, GO:0007268=TAS, GO:0007214=TAS, GO:0055085=TAS, GO:0005254=IEA, GO:0034220=TAS, GO:0005887=TAS, GO:0045211=IEA, GO:0006810=TAS, GO:0016021=IEA} gamma-aminobutyric acid signaling pathway, ion transmembrane transport, synaptic transmission, transmembrane transport, transport cell junction, chloride channel complex, integral to membrane, integral to plasma membrane, plasma membrane, postsynaptic membrane GABA-A receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity Human GABRR2 Reactome UniProtKB {GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25391, GO:0004890=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0034707=GO_REF:0000037, GO:0007268=Reactome:REACT_13685, GO:0007214=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000037, GO:0007165=PMID:1315307, GO:0034220=Reactome:REACT_25387, GO:0005887=PMID:1315307, GO:0045211=GO_REF:0000039, GO:0006810=PMID:1315307, GO:0007601=GO_REF:0000019} P28476 Gamma-aminobutyric acid receptor subunit rho-2 protein 20130301 {GO:0005230=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0004890=IEA, GO:0019904=IEA, GO:0034707=IEA, GO:0007268=TAS, GO:0007214=IEA, GO:0055085=TAS, GO:0005254=IEA, GO:0007165=TAS, GO:0034220=TAS, GO:0005887=TAS, GO:0045211=IEA, GO:0006810=TAS, GO:0007601=IEA} gamma-aminobutyric acid signaling pathway, ion transmembrane transport, signal transduction, synaptic transmission, transmembrane transport, transport, visual perception cell junction, chloride channel complex, integral to plasma membrane, plasma membrane, postsynaptic membrane GABA-A receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity, protein domain specific binding Human GABRR3 Reactome UniProtKB {GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25391, GO:0004890=PMID:10542332, GO:0019904=GO_REF:0000019, GO:0034707=GO_REF:0000037, GO:0007268=Reactome:REACT_13685, GO:0007214=PMID:10542332, GO:0005575=GO_REF:0000015, GO:0005254=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0034220=Reactome:REACT_25387, GO:0045211=GO_REF:0000039} A8MPY1 Gamma-aminobutyric acid receptor subunit rho-3 protein 20130301 {GO:0005230=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0004890=NAS, GO:0019904=IEA, GO:0034707=IEA, GO:0007268=TAS, GO:0007214=NAS, GO:0005575=ND, GO:0005254=IEA, GO:0055085=TAS, GO:0034220=TAS, GO:0045211=IEA} gamma-aminobutyric acid signaling pathway, ion transmembrane transport, synaptic transmission, transmembrane transport cell junction, cellular_component, chloride channel complex, plasma membrane, postsynaptic membrane GABA-A receptor activity, chloride channel activity, extracellular ligand-gated ion channel activity, protein domain specific binding Human GAD1 IntAct UniProtKB {GO:0012506=PMID:10671565, GO:0005515=PMID:17474147, GO:0005886=Reactome:REACT_23813, GO:0046982=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0006538=PMID:10671565, GO:0007268=Reactome:REACT_13685, GO:0018352=PMID:10671565, GO:0007269=Reactome:REACT_13723, GO:0005622=PMID:10671565, GO:0004351=PMID:10671565, GO:0047485=GO_REF:0000019, GO:0030170=GO_REF:0000002, GO:0016831=GO_REF:0000002, GO:0061202=Reactome:REACT_23973, GO:0016595=GO_REF:0000019, GO:0042136=GO_REF:0000037, GO:0006540=PMID:1549570, GO:0009449=GO_REF:0000019, GO:0019752=GO_REF:0000002} Q99259 Glutamate decarboxylase 1 protein 20130415 {GO:0012506=NAS, GO:0005515=IPI, GO:0005886=TAS, GO:0046982=IEA, GO:0042493=IEA, GO:0006538=TAS, GO:0007268=TAS, GO:0018352=TAS, GO:0007269=TAS, GO:0005622=IDA, GO:0004351=IDA, GO:0047485=IEA, GO:0030170=IEA, GO:0016831=IEA, GO:0061202=TAS, GO:0016595=IEA, GO:0042136=IEA, GO:0006540=TAS, GO:0009449=IEA, GO:0019752=IEA} carboxylic acid metabolic process, gamma-aminobutyric acid biosynthetic process, glutamate catabolic process, glutamate decarboxylation to succinate, neurotransmitter biosynthetic process, neurotransmitter secretion, protein-pyridoxal-5-phosphate linkage, response to drug, synaptic transmission clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane, intracellular, plasma membrane, vesicle membrane carboxy-lyase activity, glutamate binding, glutamate decarboxylase activity, protein N-terminus binding, protein binding, protein heterodimerization activity, pyridoxal phosphate binding Human UniProtKB:P16333 GAD2 InterPro UniProtKB {GO:0005515=PMID:10671565, GO:0030424=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_23813, GO:0046982=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0031225=GO_REF:0000019, GO:0007269=Reactome:REACT_13723, GO:0005829=GO_REF:0000039, GO:0042734=GO_REF:0000039, GO:0004351=GO_REF:0000003, GO:0000139=GO_REF:0000039, GO:0030170=GO_REF:0000002, GO:0016831=GO_REF:0000002, GO:0030672=GO_REF:0000019, GO:0061202=Reactome:REACT_23973, GO:0042136=GO_REF:0000037, GO:0016595=GO_REF:0000019, GO:0006540=GO_REF:0000019, GO:0019752=GO_REF:0000002} Q5VZ29 Glutamate decarboxylase 2 protein 20130413 {GO:0005515=IPI, GO:0030424=IEA, GO:0048471=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0046982=IEA, GO:0042493=IEA, GO:0007268=TAS, GO:0031225=IEA, GO:0007269=TAS, GO:0005829=IEA, GO:0042734=IEA, GO:0004351=IEA, GO:0000139=IEA, GO:0030170=IEA, GO:0016831=IEA, GO:0030672=IEA, GO:0061202=TAS, GO:0042136=IEA, GO:0016595=IEA, GO:0006540=IEA, GO:0019752=IEA} carboxylic acid metabolic process, glutamate decarboxylation to succinate, neurotransmitter biosynthetic process, neurotransmitter secretion, response to drug, synaptic transmission Golgi membrane, anchored to membrane, axon, cell junction, clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane, cytosol, perinuclear region of cytoplasm, plasma membrane, presynaptic membrane, synaptic vesicle membrane carboxy-lyase activity, glutamate binding, glutamate decarboxylase activity, protein binding, protein heterodimerization activity, pyridoxal phosphate binding Human InterPro:IPR002129|InterPro:IPR015421 GADD45A BHF-UCL UniProtKB {GO:0042770=PMID:20160708, GO:0005515=PMID:21988832, GO:0006281=PMID:7973727, GO:0007098=GO_REF:0000019, GO:0006915=PMID:10828065, GO:0005634=GO_REF:0000054, GO:0007050=GO_REF:0000037, GO:0000079=PMID:10747892, GO:0006469=GO_REF:0000019, GO:0071260=PMID:19593445, GO:2000379=PMID:20160708, GO:0071479=PMID:20160708} P24522 Growth arrest and DNA damage-inducible protein GADD45 alpha protein 20101021 {GO:0042770=IMP, GO:0005515=IPI, GO:0006281=TAS, GO:0007098=IEA, GO:0006915=TAS, GO:0005634=IDA, GO:0007050=IEA, GO:0000079=TAS, GO:0006469=IEA, GO:0071260=IEP, GO:2000379=IMP, GO:0071479=IMP} DNA repair, apoptotic process, cell cycle arrest, cellular response to ionizing radiation, cellular response to mechanical stimulus, centrosome cycle, negative regulation of protein kinase activity, positive regulation of reactive oxygen species metabolic process, regulation of cyclin-dependent protein serine/threonine kinase activity, signal transduction in response to DNA damage nucleus protein binding Human GADD45B ENSEMBL UniProtKB {GO:0000186=GO_REF:0000019, GO:0000185=PMID:9827804, GO:0051726=GO_REF:0000019, GO:0006950=GO_REF:0000002, GO:0006915=GO_REF:0000037, GO:0007275=GO_REF:0000037, GO:0005634=GO_REF:0000002, GO:0006469=GO_REF:0000019, GO:0030154=GO_REF:0000037} Q6IX74 Growth arrest and DNA-damage-inducible beta protein 20130413 {GO:0000186=IEA, GO:0000185=TAS, GO:0051726=IEA, GO:0006950=IEA, GO:0006915=IEA, GO:0007275=IEA, GO:0005634=IEA, GO:0006469=IEA, GO:0030154=IEA} activation of MAPKK activity, activation of MAPKKK activity, apoptotic process, cell differentiation, multicellular organismal development, negative regulation of protein kinase activity, regulation of cell cycle, response to stress nucleus Human Ensembl:ENSMUSP00000015456 GADD45G ENSEMBL UniProtKB {GO:0005515=PMID:15383276, GO:0000186=GO_REF:0000019, GO:0006281=PMID:9827804, GO:0000185=PMID:9827804, GO:0006950=GO_REF:0000002, GO:0051726=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0007275=GO_REF:0000037, GO:0005634=GO_REF:0000002, GO:0006469=GO_REF:0000019, GO:0030154=GO_REF:0000037} Q5VZ88 Growth arrest and DNA damage-inducible protein GADD45 gamma protein 20130413 {GO:0005515=IPI, GO:0000186=IEA, GO:0006281=TAS, GO:0000185=TAS, GO:0006950=IEA, GO:0051726=IEA, GO:0006915=IEA, GO:0007275=IEA, GO:0005634=IEA, GO:0006469=IEA, GO:0030154=IEA} DNA repair, activation of MAPKK activity, activation of MAPKKK activity, apoptotic process, cell differentiation, multicellular organismal development, negative regulation of protein kinase activity, regulation of cell cycle, response to stress nucleus protein binding Human Ensembl:ENSMUSP00000021903 GADD45GIP1 IntAct UniProtKB {GO:0005515=PMID:12716909, GO:0005739=GO_REF:0000039, GO:0007049=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0005634=GO_REF:0000039} Q8TAE8 Growth arrest and DNA damage-inducible proteins-interacting protein 1 protein 20130415 {GO:0005515=IPI, GO:0005739=IEA, GO:0007049=IEA, GO:0019048=IEA, GO:0005634=IEA} cell cycle, virus-host interaction mitochondrion, nucleus protein binding Human UniProtKB:P24522 GAGE1 PINC UniProtKB {GO:0006968=PMID:7544395} Q13065 G antigen 1 protein 20030904 {GO:0006968=TAS} cellular defense response Human GAGE12I null null {} null null null null {} null null null GAGE2E null null {} null null null null {} null null null GAGE5 null null {} null null null null {} null null null GAK HPA UniProtKB {GO:0005515=PMID:22645275, GO:0005737=GO_REF:0000052, GO:0048471=GO_REF:0000039, GO:0007049=GO_REF:0000037, GO:0005794=GO_REF:0000052, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000037, GO:0016301=GO_REF:0000038, GO:0005925=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0016772=GO_REF:0000002} O14976 Cyclin-G-associated kinase protein 20101115 {GO:0005515=IPI, GO:0005737=IDA, GO:0048471=IEA, GO:0007049=IEA, GO:0005794=IDA, GO:0004672=IEA, GO:0004674=IEA, GO:0016301=IEA, GO:0005925=IEA, GO:0005524=IEA, GO:0016772=IEA} cell cycle Golgi apparatus, cytoplasm, focal adhesion, perinuclear region of cytoplasm ATP binding, kinase activity, protein binding, protein kinase activity, protein serine/threonine kinase activity, transferase activity, transferring phosphorus-containing groups Human GAL Reactome UniProtKB {GO:0007631=GO_REF:0000019, GO:0032868=GO_REF:0000019, GO:0043627=GO_REF:0000019, GO:0005794=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0005576=Reactome:REACT_22289, GO:0005575=GO_REF:0000015, GO:0007399=GO_REF:0000019, GO:0050672=GO_REF:0000019, GO:0006939=GO_REF:0000029, GO:0006954=GO_REF:0000019, GO:0007218=GO_REF:0000019, GO:0030252=GO_REF:0000029, GO:0005184=PMID:1722333, GO:0030141=GO_REF:0000019, GO:0030073=PMID:1370155, GO:0031943=GO_REF:0000019} P22466 Galanin peptides protein 20081218 {GO:0007631=IEA, GO:0032868=IEA, GO:0043627=IEA, GO:0005794=IEA, GO:0043065=IEA, GO:0042493=IEA, GO:0005576=TAS, GO:0005575=ND, GO:0007399=IEA, GO:0050672=IEA, GO:0006939=NAS, GO:0006954=IEA, GO:0007218=IEA, GO:0030252=NAS, GO:0005184=NAS, GO:0030141=IEA, GO:0030073=NAS, GO:0031943=IEA} feeding behavior, growth hormone secretion, inflammatory response, insulin secretion, negative regulation of lymphocyte proliferation, nervous system development, neuropeptide signaling pathway, positive regulation of apoptotic process, regulation of glucocorticoid metabolic process, response to drug, response to estrogen stimulus, response to insulin stimulus, smooth muscle contraction Golgi apparatus, cellular_component, extracellular region, secretory granule neuropeptide hormone activity Human GAL3ST1 Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0006682=GO_REF:0000019, GO:0005794=GO_REF:0000002, GO:0001733=GO_REF:0000003, GO:0006687=Reactome:REACT_116105, GO:0009058=GO_REF:0000002, GO:0042552=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0007283=GO_REF:0000019, GO:0016020=PMID:9030544, GO:0000139=Reactome:REACT_115577, GO:0005887=PMID:9030544, GO:0008146=PMID:9030544, GO:0016021=GO_REF:0000002, GO:0006487=PMID:9030544} Q99999 Galactosylceramide sulfotransferase protein 20130301 {GO:0006665=TAS, GO:0006682=IEA, GO:0005794=IEA, GO:0001733=IEA, GO:0006687=TAS, GO:0009058=IEA, GO:0042552=IEA, GO:0044281=TAS, GO:0007283=IEA, GO:0016020=TAS, GO:0000139=TAS, GO:0005887=TAS, GO:0008146=TAS, GO:0016021=IEA, GO:0006487=TAS} biosynthetic process, galactosylceramide biosynthetic process, glycosphingolipid metabolic process, myelination, protein N-linked glycosylation, small molecule metabolic process, spermatogenesis, sphingolipid metabolic process Golgi apparatus, Golgi membrane, integral to membrane, integral to plasma membrane, membrane galactosylceramide sulfotransferase activity, sulfotransferase activity Human GAL3ST4 UniProtKB UniProtKB {GO:0006790=PMID:11333265, GO:0009311=PMID:11333265, GO:0001733=GO_REF:0000002, GO:0005794=GO_REF:0000002, GO:0009058=GO_REF:0000002, GO:0050698=PMID:11333265, GO:0007267=PMID:11333265, GO:0050694=PMID:11333265, GO:0050656=PMID:11333265, GO:0030166=PMID:11333265, GO:0009100=PMID:11333265, GO:0016020=PMID:11333265, GO:0032580=GO_REF:0000039, GO:0016021=PMID:11333265} Q96RP7 Galactose-3-O-sulfotransferase 4 protein 20031216 {GO:0006790=NAS, GO:0009311=NAS, GO:0001733=IEA, GO:0005794=IEA, GO:0009058=IEA, GO:0050698=NAS, GO:0007267=NAS, GO:0050694=IDA, GO:0050656=NAS, GO:0030166=NAS, GO:0009100=NAS, GO:0016020=IDA, GO:0032580=IEA, GO:0016021=NAS} biosynthetic process, cell-cell signaling, glycoprotein metabolic process, oligosaccharide metabolic process, proteoglycan biosynthetic process, sulfur compound metabolic process Golgi apparatus, Golgi cisterna membrane, integral to membrane, membrane 3'-phosphoadenosine 5'-phosphosulfate binding, galactose 3-O-sulfotransferase activity, galactosylceramide sulfotransferase activity, proteoglycan sulfotransferase activity Human GALC Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0005739=GO_REF:0000019, GO:0006683=GO_REF:0000002, GO:0006687=Reactome:REACT_116105, GO:0005975=GO_REF:0000002, GO:0004336=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0005764=PMID:7601472, GO:0043202=Reactome:REACT_115737} P54803 Galactocerebrosidase protein 20130301 {GO:0006665=TAS, GO:0005739=IEA, GO:0006683=IEA, GO:0006687=TAS, GO:0005975=IEA, GO:0004336=IEA, GO:0044281=TAS, GO:0005764=TAS, GO:0043202=TAS} carbohydrate metabolic process, galactosylceramide catabolic process, glycosphingolipid metabolic process, small molecule metabolic process, sphingolipid metabolic process lysosomal lumen, lysosome, mitochondrion galactosylceramidase activity Human GALE InterPro UniProtKB {GO:0050662=GO_REF:0000002, GO:0003978=GO_REF:0000002, GO:0005975=Reactome:REACT_474, GO:0019388=Reactome:REACT_532, GO:0044281=Reactome:REACT_111217, GO:0006012=GO_REF:0000002, GO:0042803=PMID:16302980, GO:0044237=GO_REF:0000002, GO:0005829=Reactome:REACT_1315} Q5QPP9 UDP-glucose 4-epimerase protein 20130413 {GO:0050662=IEA, GO:0003978=IEA, GO:0005975=TAS, GO:0019388=TAS, GO:0044281=TAS, GO:0006012=IEA, GO:0042803=IPI, GO:0044237=IEA, GO:0005829=TAS} carbohydrate metabolic process, cellular metabolic process, galactose catabolic process, galactose metabolic process, small molecule metabolic process cytosol UDP-glucose 4-epimerase activity, coenzyme binding, protein homodimerization activity Human InterPro:IPR005886 GALK1 Reactome UniProtKB {GO:0004335=PMID:12694189, GO:0005737=PMID:8908517, GO:0005534=PMID:14596685, GO:0016020=PMID:8908517, GO:0005975=Reactome:REACT_474, GO:0019388=Reactome:REACT_532, GO:0044281=Reactome:REACT_111217, GO:0006012=PMID:15024738, GO:0005524=PMID:12694189, GO:0005829=Reactome:REACT_1246} P51570 Galactokinase protein 20130301 {GO:0004335=IDA, GO:0005737=IDA, GO:0005534=IDA, GO:0016020=IDA, GO:0005975=TAS, GO:0019388=TAS, GO:0044281=TAS, GO:0006012=IMP, GO:0005524=IDA, GO:0005829=TAS} carbohydrate metabolic process, galactose catabolic process, galactose metabolic process, small molecule metabolic process cytoplasm, cytosol, membrane ATP binding, galactokinase activity, galactose binding Human GALK2 PINC UniProtKB {GO:0004335=PMID:7542884, GO:0005737=GO_REF:0000002, GO:0033858=GO_REF:0000003, GO:0005975=PMID:8798585, GO:0016301=GO_REF:0000038, GO:0016773=GO_REF:0000002, GO:0006012=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q01415 N-acetylgalactosamine kinase protein 20030904 {GO:0004335=IDA, GO:0005737=IEA, GO:0033858=IEA, GO:0005975=TAS, GO:0016301=IEA, GO:0016773=IEA, GO:0006012=IEA, GO:0005524=IEA} carbohydrate metabolic process, galactose metabolic process cytoplasm ATP binding, N-acetylgalactosamine kinase activity, galactokinase activity, kinase activity, phosphotransferase activity, alcohol group as acceptor Human GALM UniPathway UniProtKB {GO:0005737=GO_REF:0000039, GO:0004034=GO_REF:0000003, GO:0030246=GO_REF:0000002, GO:0019318=GO_REF:0000041, GO:0016853=GO_REF:0000002} Q96C23 Aldose 1-epimerase protein 20130413 {GO:0005737=IEA, GO:0004034=IEA, GO:0030246=IEA, GO:0019318=IEA, GO:0016853=IEA} hexose metabolic process cytoplasm aldose 1-epimerase activity, carbohydrate binding, isomerase activity Human UniPathway:UPA00242 GALNS Reactome UniProtKB {GO:0003943=PMID:8325655, GO:0043890=GO_REF:0000003, GO:0005975=Reactome:REACT_474, GO:0042340=Reactome:REACT_121313, GO:0044281=Reactome:REACT_111217, GO:0008484=PMID:15962010, GO:0030203=Reactome:REACT_121315, GO:0046872=GO_REF:0000037, GO:0043202=Reactome:REACT_121094, GO:0042339=Reactome:REACT_121288} P34059 N-acetylgalactosamine-6-sulfatase protein 20130301 {GO:0003943=TAS, GO:0043890=IEA, GO:0005975=TAS, GO:0042340=TAS, GO:0044281=TAS, GO:0008484=IDA, GO:0030203=TAS, GO:0046872=IEA, GO:0043202=TAS, GO:0042339=TAS} carbohydrate metabolic process, glycosaminoglycan metabolic process, keratan sulfate catabolic process, keratan sulfate metabolic process, small molecule metabolic process lysosomal lumen N-acetylgalactosamine-4-sulfatase activity, N-acetylgalactosamine-6-sulfatase activity, metal ion binding, sulfuric ester hydrolase activity Human GALNT1 BHF-UCL UniProtKB {GO:0048471=PMID:12506059, GO:0030145=PMID:9295285, GO:0005794=PMID:12506059, GO:0016757=GO_REF:0000038, GO:0016266=Reactome:REACT_115606, GO:0005576=GO_REF:0000039, GO:0004653=PMID:9295285, GO:0006493=PMID:9592121, GO:0000139=Reactome:REACT_115586, GO:0018242=PMID:9295285, GO:0032580=GO_REF:0000039, GO:0018243=PMID:9295285, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q10472 Polypeptide N-acetylgalactosaminyltransferase 1 protein 20080306 {GO:0048471=IDA, GO:0030145=IDA, GO:0005794=IDA, GO:0016757=IEA, GO:0016266=TAS, GO:0005576=IEA, GO:0004653=IDA, GO:0006493=TAS, GO:0000139=TAS, GO:0018242=IDA, GO:0032580=IEA, GO:0018243=IDA, GO:0016021=IEA, GO:0044267=TAS, GO:0043687=TAS} O-glycan processing, cellular protein metabolic process, post-translational protein modification, protein O-linked glycosylation, protein O-linked glycosylation via serine, protein O-linked glycosylation via threonine Golgi apparatus, Golgi cisterna membrane, Golgi membrane, extracellular region, integral to membrane, perinuclear region of cytoplasm manganese ion binding, polypeptide N-acetylgalactosaminyltransferase activity, transferase activity, transferring glycosyl groups Human GALNT10 Reactome UniProtKB {GO:0004653=GO_REF:0000003, GO:0000139=Reactome:REACT_115586, GO:0016757=GO_REF:0000038, GO:0016266=Reactome:REACT_115606, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0046872=GO_REF:0000037, GO:0043687=Reactome:REACT_22161} Q86SR1 Polypeptide N-acetylgalactosaminyltransferase 10 protein 20130301 {GO:0004653=IEA, GO:0000139=TAS, GO:0016757=IEA, GO:0016266=TAS, GO:0016021=IEA, GO:0044267=TAS, GO:0046872=IEA, GO:0043687=TAS} O-glycan processing, cellular protein metabolic process, post-translational protein modification Golgi membrane, integral to membrane metal ion binding, polypeptide N-acetylgalactosaminyltransferase activity, transferase activity, transferring glycosyl groups Human GALNT11 Reactome UniProtKB {GO:0004653=GO_REF:0000003, GO:0005794=GO_REF:0000038, GO:0000139=Reactome:REACT_115586, GO:0016757=GO_REF:0000038, GO:0016266=Reactome:REACT_115606, GO:0006486=GO_REF:0000041, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0016740=GO_REF:0000038, GO:0043687=Reactome:REACT_22161} Q8NCW6 Polypeptide N-acetylgalactosaminyltransferase 11 protein 20130301 {GO:0004653=IEA, GO:0005794=IEA, GO:0000139=TAS, GO:0016757=IEA, GO:0016266=TAS, GO:0006486=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0016740=IEA, GO:0043687=TAS} O-glycan processing, cellular protein metabolic process, post-translational protein modification, protein glycosylation Golgi apparatus, Golgi membrane, integral to membrane polypeptide N-acetylgalactosaminyltransferase activity, transferase activity, transferase activity, transferring glycosyl groups Human GALNT12 Reactome UniProtKB {GO:0004653=GO_REF:0000003, GO:0000139=Reactome:REACT_115586, GO:0016266=Reactome:REACT_115606, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q8IXK2 Polypeptide N-acetylgalactosaminyltransferase 12 protein 20130301 {GO:0004653=IEA, GO:0000139=TAS, GO:0016266=TAS, GO:0016021=IEA, GO:0044267=TAS, GO:0043687=TAS} O-glycan processing, cellular protein metabolic process, post-translational protein modification Golgi membrane, integral to membrane polypeptide N-acetylgalactosaminyltransferase activity Human GALNT13 Reactome UniProtKB {GO:0004653=GO_REF:0000003, GO:0005794=GO_REF:0000038, GO:0000139=Reactome:REACT_115586, GO:0016757=GO_REF:0000038, GO:0016266=Reactome:REACT_115606, GO:0006486=GO_REF:0000041, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q8IUC8 Polypeptide N-acetylgalactosaminyltransferase 13 protein 20130301 {GO:0004653=IEA, GO:0005794=IEA, GO:0000139=TAS, GO:0016757=IEA, GO:0016266=TAS, GO:0006486=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0043687=TAS} O-glycan processing, cellular protein metabolic process, post-translational protein modification, protein glycosylation Golgi apparatus, Golgi membrane, integral to membrane polypeptide N-acetylgalactosaminyltransferase activity, transferase activity, transferring glycosyl groups Human GALNT14 Reactome UniProtKB {GO:0004653=GO_REF:0000003, GO:0005794=GO_REF:0000038, GO:0000139=Reactome:REACT_115586, GO:0005975=GO_REF:0000002, GO:0016757=GO_REF:0000038, GO:0016266=Reactome:REACT_115606, GO:0006486=GO_REF:0000041, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q96FL9 Polypeptide N-acetylgalactosaminyltransferase 14 protein 20130301 {GO:0004653=IEA, GO:0005794=IEA, GO:0000139=TAS, GO:0005975=IEA, GO:0016757=IEA, GO:0016266=TAS, GO:0006486=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0043687=TAS} O-glycan processing, carbohydrate metabolic process, cellular protein metabolic process, post-translational protein modification, protein glycosylation Golgi apparatus, Golgi membrane, integral to membrane polypeptide N-acetylgalactosaminyltransferase activity, transferase activity, transferring glycosyl groups Human GALNT2 HPA UniProtKB {GO:0048471=PMID:12506059, GO:0030145=PMID:9295285, GO:0005794=GO_REF:0000052, GO:0005795=PMID:9852147, GO:0016757=GO_REF:0000038, GO:0016266=Reactome:REACT_115606, GO:0005576=GO_REF:0000039, GO:0002378=PMID:12438318, GO:0004653=PMID:9295285, GO:0030173=PMID:9852147, GO:0000139=Reactome:REACT_115586, GO:0018242=PMID:9295285, GO:0032580=GO_REF:0000039, GO:0018243=PMID:9295285, GO:0006486=GO_REF:0000041, GO:0016021=GO_REF:0000038, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q10471 Polypeptide N-acetylgalactosaminyltransferase 2 protein 20081203 {GO:0048471=IDA, GO:0030145=IDA, GO:0005794=IDA, GO:0005795=IDA, GO:0016757=IEA, GO:0016266=TAS, GO:0005576=IEA, GO:0002378=IDA, GO:0004653=IDA, GO:0030173=NAS, GO:0000139=TAS, GO:0018242=IDA, GO:0032580=IEA, GO:0018243=IDA, GO:0006486=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0043687=TAS} O-glycan processing, cellular protein metabolic process, immunoglobulin biosynthetic process, post-translational protein modification, protein O-linked glycosylation via serine, protein O-linked glycosylation via threonine, protein glycosylation Golgi apparatus, Golgi cisterna membrane, Golgi membrane, Golgi stack, extracellular region, integral to Golgi membrane, integral to membrane, perinuclear region of cytoplasm manganese ion binding, polypeptide N-acetylgalactosaminyltransferase activity, transferase activity, transferring glycosyl groups Human GALNT4 BHF-UCL UniProtKB {GO:0048471=PMID:12506059, GO:0004653=GO_REF:0000003, GO:0005794=PMID:12506059, GO:0000139=Reactome:REACT_115586, GO:0005975=PMID:9592121, GO:0016266=Reactome:REACT_115606, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q8N4A0 Polypeptide N-acetylgalactosaminyltransferase 4 protein 20080306 {GO:0048471=IDA, GO:0004653=IEA, GO:0005794=IDA, GO:0000139=TAS, GO:0005975=NAS, GO:0016266=TAS, GO:0016021=IEA, GO:0044267=TAS, GO:0043687=TAS} O-glycan processing, carbohydrate metabolic process, cellular protein metabolic process, post-translational protein modification Golgi apparatus, Golgi membrane, integral to membrane, perinuclear region of cytoplasm polypeptide N-acetylgalactosaminyltransferase activity Human GALNT5 Reactome UniProtKB {GO:0004653=PMID:10545594, GO:0000139=Reactome:REACT_115586, GO:0016266=Reactome:REACT_115606, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006024=PMID:10545594, GO:0043687=Reactome:REACT_22161} Q7Z7M9 Polypeptide N-acetylgalactosaminyltransferase 5 protein 20130301 {GO:0004653=IDA, GO:0000139=TAS, GO:0016266=TAS, GO:0005575=ND, GO:0016021=IEA, GO:0044267=TAS, GO:0006024=TAS, GO:0043687=TAS} O-glycan processing, cellular protein metabolic process, glycosaminoglycan biosynthetic process, post-translational protein modification Golgi membrane, cellular_component, integral to membrane polypeptide N-acetylgalactosaminyltransferase activity Human GALNT6 BHF-UCL UniProtKB {GO:0048471=PMID:12506059, GO:0004653=GO_REF:0000003, GO:0005794=PMID:12506059, GO:0000139=Reactome:REACT_115586, GO:0006493=PMID:10464263, GO:0016266=Reactome:REACT_115606, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q8NCL4 Polypeptide N-acetylgalactosaminyltransferase 6 protein 20080306 {GO:0048471=IDA, GO:0004653=IEA, GO:0005794=IDA, GO:0000139=TAS, GO:0006493=TAS, GO:0016266=TAS, GO:0016021=IEA, GO:0044267=TAS, GO:0043687=TAS} O-glycan processing, cellular protein metabolic process, post-translational protein modification, protein O-linked glycosylation Golgi apparatus, Golgi membrane, integral to membrane, perinuclear region of cytoplasm polypeptide N-acetylgalactosaminyltransferase activity Human GALNT7 Reactome UniProtKB {GO:0004653=GO_REF:0000019, GO:0005794=GO_REF:0000038, GO:0000139=Reactome:REACT_115586, GO:0006493=PMID:10544240, GO:0005975=PMID:10544240, GO:0016757=GO_REF:0000038, GO:0016266=Reactome:REACT_115606, GO:0006486=GO_REF:0000041, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q86SF2 N-acetylgalactosaminyltransferase 7 protein 20130301 {GO:0004653=IEA, GO:0005794=IEA, GO:0000139=TAS, GO:0006493=TAS, GO:0005975=TAS, GO:0016757=IEA, GO:0016266=TAS, GO:0006486=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0043687=TAS} O-glycan processing, carbohydrate metabolic process, cellular protein metabolic process, post-translational protein modification, protein O-linked glycosylation, protein glycosylation Golgi apparatus, Golgi membrane, integral to membrane polypeptide N-acetylgalactosaminyltransferase activity, transferase activity, transferring glycosyl groups Human GALNTL5 UniPathway UniProtKB {GO:0000139=GO_REF:0000039, GO:0016757=GO_REF:0000037, GO:0006486=GO_REF:0000041, GO:0016021=GO_REF:0000037, GO:0016740=GO_REF:0000038} Q7Z4T8 Putative polypeptide N-acetylgalactosaminyltransferase-like protein 5 protein 20130413 {GO:0000139=IEA, GO:0016757=IEA, GO:0006486=IEA, GO:0016021=IEA, GO:0016740=IEA} protein glycosylation Golgi membrane, integral to membrane transferase activity, transferase activity, transferring glycosyl groups Human UniPathway:UPA00378 GALR1 Reactome UniProtKB {GO:0005886=Reactome:REACT_22289, GO:0042923=GO_REF:0000019, GO:0007218=PMID:7524088, GO:0007586=PMID:8670213, GO:0004966=GO_REF:0000019, GO:0007189=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007194=PMID:7524088} P47211 Galanin receptor type 1 protein 20081218 {GO:0005886=TAS, GO:0042923=IEA, GO:0007218=TAS, GO:0007586=TAS, GO:0004966=IEA, GO:0007189=IEA, GO:0016021=IEA, GO:0007194=TAS} adenylate cyclase-activating G-protein coupled receptor signaling pathway, digestion, negative regulation of adenylate cyclase activity, neuropeptide signaling pathway integral to membrane, plasma membrane galanin receptor activity, neuropeptide binding Human GALR2 Reactome UniProtKB {GO:0007631=PMID:9480833, GO:0005886=Reactome:REACT_22289, GO:0007586=PMID:9832121, GO:0004966=GO_REF:0000002, GO:0007268=PMID:9832121, GO:0007275=PMID:9480833, GO:0007204=PMID:9685625, GO:0031175=GO_REF:0000019, GO:0006936=PMID:9480833, GO:0007611=PMID:9480833, GO:0007188=PMID:9685625, GO:0016021=GO_REF:0000037, GO:0007166=PMID:9480833} O43603 Galanin receptor type 2 protein 20081218 {GO:0007631=TAS, GO:0005886=TAS, GO:0007586=TAS, GO:0004966=IEA, GO:0007268=TAS, GO:0007275=TAS, GO:0007204=TAS, GO:0031175=IEA, GO:0006936=TAS, GO:0007611=TAS, GO:0007188=TAS, GO:0016021=IEA, GO:0007166=TAS} adenylate cyclase-modulating G-protein coupled receptor signaling pathway, cell surface receptor signaling pathway, digestion, elevation of cytosolic calcium ion concentration, feeding behavior, learning or memory, multicellular organismal development, muscle contraction, neuron projection development, synaptic transmission integral to membrane, plasma membrane galanin receptor activity Human GALR3 Reactome UniProtKB {GO:0007631=PMID:9722565, GO:0005886=Reactome:REACT_22289, GO:0007218=PMID:9722565, GO:0007611=PMID:9722565, GO:0007268=PMID:9722565, GO:0004966=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007194=PMID:9832121} O60755 Galanin receptor type 3 protein 20081218 {GO:0007631=TAS, GO:0005886=TAS, GO:0007218=TAS, GO:0007611=TAS, GO:0007268=TAS, GO:0004966=IEA, GO:0016021=IEA, GO:0007194=TAS} feeding behavior, learning or memory, negative regulation of adenylate cyclase activity, neuropeptide signaling pathway, synaptic transmission integral to membrane, plasma membrane galanin receptor activity Human GALT Reactome UniProtKB {GO:0005794=PMID:20605918, GO:0005975=Reactome:REACT_474, GO:0008108=GO_REF:0000003, GO:0019388=Reactome:REACT_532, GO:0006258=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0006012=PMID:1427861, GO:0005829=Reactome:REACT_2047} P07902 Galactose-1-phosphate uridylyltransferase protein 20130301 {GO:0005794=IDA, GO:0005975=TAS, GO:0008108=IEA, GO:0019388=TAS, GO:0006258=IEA, GO:0008270=IEA, GO:0044281=TAS, GO:0006012=TAS, GO:0005829=TAS} UDP-glucose catabolic process, carbohydrate metabolic process, galactose catabolic process, galactose metabolic process, small molecule metabolic process Golgi apparatus, cytosol UDP-glucose:hexose-1-phosphate uridylyltransferase activity, zinc ion binding Human GAMT Reactome UniProtKB {GO:0030731=PMID:8651275, GO:0034641=Reactome:REACT_13, GO:0006936=PMID:8547310, GO:0006601=PMID:8651275, GO:0006600=Reactome:REACT_813, GO:0008168=PMID:9325156, GO:0040014=GO_REF:0000019, GO:0009887=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0007283=GO_REF:0000019, GO:0005829=Reactome:REACT_2094} Q14353 Guanidinoacetate N-methyltransferase protein 20130301 {GO:0030731=IMP, GO:0034641=TAS, GO:0006936=TAS, GO:0006601=IDA, GO:0006600=TAS, GO:0008168=TAS, GO:0040014=IEA, GO:0009887=IEA, GO:0044281=TAS, GO:0007283=IEA, GO:0005829=TAS} cellular nitrogen compound metabolic process, creatine biosynthetic process, creatine metabolic process, muscle contraction, organ morphogenesis, regulation of multicellular organism growth, small molecule metabolic process, spermatogenesis cytosol guanidinoacetate N-methyltransferase activity, methyltransferase activity Human GAN IntAct UniProtKB {GO:0005515=PMID:16303566, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0008219=GO_REF:0000037, GO:0005737=PMID:19424503, GO:0016567=PMID:15983046, GO:0005883=GO_REF:0000029, GO:0031463=PMID:15983046} Q9H2C0 Gigaxonin protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0003674=ND, GO:0008219=IEA, GO:0005737=IDA, GO:0016567=IDA, GO:0005883=NAS, GO:0031463=IDA} biological_process, cell death, protein ubiquitination Cul3-RING ubiquitin ligase complex, cytoplasm, neurofilament molecular_function, protein binding Human UniProtKB:Q99426 GANAB Reactome UniProtKB {GO:0033919=GO_REF:0000003, GO:0042470=GO_REF:0000039, GO:0017177=GO_REF:0000019, GO:0005794=GO_REF:0000039, GO:0006457=Reactome:REACT_23878, GO:0005975=GO_REF:0000002, GO:0005788=Reactome:REACT_23850, GO:0030246=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0004553=GO_REF:0000002, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q14697 Neutral alpha-glucosidase AB protein 20100302 {GO:0033919=IEA, GO:0042470=IEA, GO:0017177=IEA, GO:0005794=IEA, GO:0006457=TAS, GO:0005975=IEA, GO:0005788=TAS, GO:0030246=IEA, GO:0044267=TAS, GO:0004553=IEA, GO:0043687=TAS, GO:0018279=TAS} carbohydrate metabolic process, cellular protein metabolic process, post-translational protein modification, protein N-linked glycosylation via asparagine, protein folding Golgi apparatus, endoplasmic reticulum lumen, glucosidase II complex, melanosome carbohydrate binding, glucan 1,3-alpha-glucosidase activity, hydrolase activity, hydrolyzing O-glycosyl compounds Human GANC UniProtKB UniProtKB {GO:0032450=GO_REF:0000003, GO:0005975=GO_REF:0000002, GO:0030246=GO_REF:0000002, GO:0004553=GO_REF:0000002, GO:0004558=PMID:12370436} Q8TET4 Neutral alpha-glucosidase C protein 20041109 {GO:0032450=IEA, GO:0005975=IEA, GO:0030246=IEA, GO:0004553=IEA, GO:0004558=NAS} carbohydrate metabolic process alpha-glucosidase activity, carbohydrate binding, hydrolase activity, hydrolyzing O-glycosyl compounds, maltose alpha-glucosidase activity Human GAP43 IntAct UniProtKB {GO:0005515=PMID:9139733, GO:0005516=GO_REF:0000037, GO:0030424=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000054, GO:0009611=PMID:3272162, GO:0031527=PMID:14978216, GO:0032584=GO_REF:0000039, GO:0045202=GO_REF:0000039, GO:0042246=GO_REF:0000019, GO:0007205=PMID:3272162, GO:0051489=PMID:14978216, GO:0045165=GO_REF:0000019, GO:0016198=GO_REF:0000019, GO:0010001=GO_REF:0000019, GO:0040008=GO_REF:0000037} P17677 Neuromodulin protein 20130415 {GO:0005515=IPI, GO:0005516=IEA, GO:0030424=IEA, GO:0030054=IEA, GO:0005886=IDA, GO:0009611=TAS, GO:0031527=IDA, GO:0032584=IEA, GO:0045202=IEA, GO:0042246=IEA, GO:0007205=TAS, GO:0051489=IDA, GO:0045165=IEA, GO:0016198=IEA, GO:0010001=IEA, GO:0040008=IEA} axon choice point recognition, cell fate commitment, glial cell differentiation, protein kinase C-activating G-protein coupled receptor signaling pathway, regulation of filopodium assembly, regulation of growth, response to wounding, tissue regeneration axon, cell junction, filopodium membrane, growth cone membrane, plasma membrane, synapse calmodulin binding, protein binding Human UniProtKB:Q05655 GAPDH HPA UniProtKB {GO:0017148=PMID:23071094, GO:0008017=GO_REF:0000024, GO:0050661=GO_REF:0000002, GO:0005515=PMID:20029029, GO:0035605=GO_REF:0000024, GO:0048471=GO_REF:0000039, GO:0005886=GO_REF:0000052, GO:0005975=Reactome:REACT_474, GO:0006094=Reactome:REACT_1520, GO:0050821=GO_REF:0000024, GO:0000226=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0004365=GO_REF:0000024, GO:0051402=GO_REF:0000024, GO:0006096=Reactome:REACT_1383, GO:0035606=GO_REF:0000024, GO:0005829=Reactome:REACT_1847, GO:0005737=GO_REF:0000052, GO:0051287=GO_REF:0000002, GO:0071346=PMID:15479637, GO:0030529=PMID:15479637, GO:0015630=GO_REF:0000024, GO:0006006=Reactome:REACT_723} P04406 Glyceraldehyde-3-phosphate dehydrogenase protein 20120912 {GO:0017148=IDA, GO:0008017=ISS, GO:0050661=IEA, GO:0005515=IPI, GO:0035605=ISS, GO:0048471=IEA, GO:0005886=IDA, GO:0005975=TAS, GO:0006094=TAS, GO:0050821=ISS, GO:0000226=ISS, GO:0005634=ISS, GO:0044281=TAS, GO:0004365=ISS, GO:0051402=ISS, GO:0006096=TAS, GO:0035606=ISS, GO:0005829=TAS, GO:0005737=IDA, GO:0051287=IEA, GO:0071346=IDA, GO:0030529=IDA, GO:0015630=ISS, GO:0006006=TAS} carbohydrate metabolic process, cellular response to interferon-gamma, gluconeogenesis, glucose metabolic process, glycolysis, microtubule cytoskeleton organization, negative regulation of translation, neuron apoptotic process, peptidyl-cysteine S-trans-nitrosylation, protein stabilization, small molecule metabolic process cytoplasm, cytosol, microtubule cytoskeleton, nucleus, perinuclear region of cytoplasm, plasma membrane, ribonucleoprotein complex NAD binding, NADP binding, glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity, microtubule binding, peptidyl-cysteine S-nitrosylase activity, protein binding Human GAPDHS Reactome UniProtKB {GO:0050661=GO_REF:0000002, GO:0005515=PMID:16820410, GO:0005975=Reactome:REACT_474, GO:0007286=GO_REF:0000019, GO:0006094=Reactome:REACT_1520, GO:0044281=Reactome:REACT_111217, GO:0030317=GO_REF:0000024, GO:0004365=PMID:10714828, GO:0006096=Reactome:REACT_1383, GO:0005829=Reactome:REACT_1847, GO:0051287=GO_REF:0000002, GO:0016620=GO_REF:0000002, GO:0006006=Reactome:REACT_723, GO:0045821=PMID:10714828} O14556 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific protein 20130213 {GO:0050661=IEA, GO:0005515=IPI, GO:0005975=TAS, GO:0007286=IEA, GO:0006094=TAS, GO:0044281=TAS, GO:0030317=ISS, GO:0004365=TAS, GO:0006096=TAS, GO:0005829=TAS, GO:0051287=IEA, GO:0016620=IEA, GO:0006006=TAS, GO:0045821=TAS} carbohydrate metabolic process, gluconeogenesis, glucose metabolic process, glycolysis, positive regulation of glycolysis, small molecule metabolic process, sperm motility, spermatid development cytosol NAD binding, NADP binding, glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, protein binding Human GAPVD1 UniProtKB UniProtKB {GO:0032794=PMID:16410077, GO:0005085=PMID:16410077, GO:0005622=GO_REF:0000002, GO:0051056=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0005768=GO_REF:0000039, GO:0006897=GO_REF:0000037, GO:0051223=PMID:16410077, GO:0005829=PMID:16410077, GO:0005096=GO_REF:0000037} Q14C86 GTPase-activating protein and VPS9 domain-containing protein 1 protein 20080314 {GO:0032794=IMP, GO:0005085=IMP, GO:0005622=IEA, GO:0051056=IEA, GO:0007165=IEA, GO:0016020=IEA, GO:0005768=IEA, GO:0006897=IEA, GO:0051223=IMP, GO:0005829=IDA, GO:0005096=IEA} endocytosis, regulation of protein transport, regulation of small GTPase mediated signal transduction, signal transduction cytosol, endosome, intracellular, membrane GTPase activating protein binding, GTPase activator activity, guanyl-nucleotide exchange factor activity Human GAR1 PINC UniProtKB {GO:0009982=GO_REF:0000002, GO:0005261=PMID:8766832, GO:0015030=GO_REF:0000039, GO:0030515=GO_REF:0000002, GO:0031429=GO_REF:0000002, GO:0006364=GO_REF:0000037, GO:0031120=GO_REF:0000002} Q9NY12 H/ACA ribonucleoprotein complex subunit 1 protein 20030904 {GO:0009982=IEA, GO:0005261=TAS, GO:0015030=IEA, GO:0030515=IEA, GO:0031429=IEA, GO:0006364=IEA, GO:0031120=IEA} rRNA processing, snRNA pseudouridine synthesis Cajal body, box H/ACA snoRNP complex cation channel activity, pseudouridine synthase activity, snoRNA binding Human GARNL3 UniProtKB UniProtKB {GO:0051056=GO_REF:0000002, GO:0005083=GO_REF:0000002, GO:0005096=GO_REF:0000037} Q5VVW2 GTPase-activating Rap/Ran-GAP domain-like protein 3 protein 20130413 {GO:0051056=IEA, GO:0005083=IEA, GO:0005096=IEA} regulation of small GTPase mediated signal transduction GTPase activator activity, small GTPase regulator activity Human UniProtKB-KW:KW-0343 GARS HPA UniProtKB {GO:0010467=Reactome:REACT_71, GO:0008219=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0015966=PMID:19710017, GO:0005759=Reactome:REACT_15471, GO:0046983=PMID:17545306, GO:0030141=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0006426=GO_REF:0000002, GO:0006418=Reactome:REACT_15482, GO:0005829=Reactome:REACT_15522, GO:0004820=Reactome:REACT_15522} P41250 Glycine--tRNA ligase protein 20101115 {GO:0010467=TAS, GO:0008219=IEA, GO:0005737=IDA, GO:0015966=IDA, GO:0005759=TAS, GO:0046983=IDA, GO:0030141=IEA, GO:0005524=IEA, GO:0006426=IEA, GO:0006418=TAS, GO:0005829=TAS, GO:0004820=TAS} cell death, diadenosine tetraphosphate biosynthetic process, gene expression, glycyl-tRNA aminoacylation, tRNA aminoacylation for protein translation cytoplasm, cytosol, mitochondrial matrix, secretory granule ATP binding, glycine-tRNA ligase activity, protein dimerization activity Human GART Reactome UniProtKB {GO:0009168=Reactome:REACT_1776, GO:0008168=GO_REF:0000002, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0004637=GO_REF:0000003, GO:0003824=GO_REF:0000002, GO:0004644=GO_REF:0000003, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_1917, GO:0005737=GO_REF:0000002, GO:0004641=GO_REF:0000003, GO:0006144=Reactome:REACT_522, GO:0009113=GO_REF:0000002, GO:0006189=GO_REF:0000041} P22102 Trifunctional purine biosynthetic protein adenosine-3 protein 20130301 {GO:0009168=TAS, GO:0008168=IEA, GO:0055086=TAS, GO:0044281=TAS, GO:0004637=IEA, GO:0003824=IEA, GO:0004644=IEA, GO:0005524=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0005737=IEA, GO:0004641=IEA, GO:0006144=TAS, GO:0009113=IEA, GO:0006189=IEA} 'de novo' IMP biosynthetic process, nucleobase-containing small molecule metabolic process, purine nucleobase biosynthetic process, purine nucleobase metabolic process, purine ribonucleoside monophosphate biosynthetic process, small molecule metabolic process cytoplasm, cytosol ATP binding, catalytic activity, metal ion binding, methyltransferase activity, phosphoribosylamine-glycine ligase activity, phosphoribosylformylglycinamidine cyclo-ligase activity, phosphoribosylglycinamide formyltransferase activity Human GAS1 MGI UniProtKB {GO:0005515=PMID:21357679, GO:0035924=PMID:15070677, GO:0030308=GO_REF:0000019, GO:0005886=PMID:8127893, GO:0060628=PMID:21357679, GO:0050680=GO_REF:0000019, GO:0045879=GO_REF:0000019, GO:0048592=GO_REF:0000019, GO:0048701=GO_REF:0000019, GO:0045880=GO_REF:0000019, GO:0048589=GO_REF:0000024, GO:0007411=GO_REF:0000019, GO:0042476=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:0007050=GO_REF:0000037, GO:0021904=GO_REF:0000019, GO:0042474=GO_REF:0000019, GO:0043010=GO_REF:0000019, GO:0042473=GO_REF:0000019, GO:0046658=GO_REF:0000024, GO:0050679=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0021587=GO_REF:0000019, GO:0002053=GO_REF:0000019, GO:0042981=GO_REF:0000024, GO:0012501=GO_REF:0000019, GO:0045165=GO_REF:0000024, GO:0045930=PMID:11356029, GO:0008589=GO_REF:0000024, GO:0016021=PMID:8127893, GO:0042733=GO_REF:0000019} P54826 Growth arrest-specific protein 1 protein 20080820 {GO:0005515=IPI, GO:0035924=IEP, GO:0030308=IEA, GO:0005886=IDA, GO:0060628=IMP, GO:0050680=IEA, GO:0045879=IEA, GO:0048592=IEA, GO:0048701=IEA, GO:0045880=IEA, GO:0048589=ISS, GO:0007411=IEA, GO:0042476=IEA, GO:0060021=IEA, GO:0007050=IEA, GO:0021904=IEA, GO:0042474=IEA, GO:0043010=IEA, GO:0042473=IEA, GO:0046658=ISS, GO:0050679=IEA, GO:0043066=IEA, GO:0021587=IEA, GO:0002053=IEA, GO:0042981=ISS, GO:0012501=IEA, GO:0045165=ISS, GO:0045930=IGI, GO:0008589=ISS, GO:0016021=NAS, GO:0042733=IEA} axon guidance, camera-type eye development, cell cycle arrest, cell fate commitment, cellular response to vascular endothelial growth factor stimulus, cerebellum morphogenesis, developmental growth, dorsal/ventral neural tube patterning, embryonic cranial skeleton morphogenesis, embryonic digit morphogenesis, eye morphogenesis, middle ear morphogenesis, negative regulation of apoptotic process, negative regulation of cell growth, negative regulation of epithelial cell proliferation, negative regulation of mitotic cell cycle, negative regulation of smoothened signaling pathway, odontogenesis, outer ear morphogenesis, palate development, positive regulation of epithelial cell proliferation, positive regulation of mesenchymal cell proliferation, positive regulation of smoothened signaling pathway, programmed cell death, regulation of ER to Golgi vesicle-mediated transport, regulation of apoptotic process, regulation of smoothened signaling pathway anchored to plasma membrane, integral to membrane, plasma membrane protein binding Human UniProtKB:P04637 GAS2 Reactome UniProtKB {GO:0016020=GO_REF:0000039, GO:0005884=PMID:1607387, GO:0008360=GO_REF:0000037, GO:0006915=Reactome:REACT_578, GO:0007050=GO_REF:0000037, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_12004} O43903 Growth arrest-specific protein 2 protein 20130301 {GO:0016020=IEA, GO:0005884=TAS, GO:0008360=IEA, GO:0006915=TAS, GO:0007050=IEA, GO:0006921=TAS, GO:0005829=TAS} apoptotic process, cell cycle arrest, cellular component disassembly involved in execution phase of apoptosis, regulation of cell shape actin filament, cytosol, membrane Human GAS2L1 UniProtKB UniProtKB {GO:0046966=PMID:19375645, GO:0097067=PMID:19375645, GO:0005737=GO_REF:0000037, GO:0001725=GO_REF:0000019, GO:0005874=GO_REF:0000019, GO:0007050=PMID:12584248, GO:0009267=PMID:12584248} Q99501 GAS2-like protein 1 protein 20111029 {GO:0046966=IDA, GO:0097067=IDA, GO:0005737=IEA, GO:0001725=IEA, GO:0005874=IEA, GO:0007050=ISS, GO:0009267=ISS} cell cycle arrest, cellular response to starvation, cellular response to thyroid hormone stimulus cytoplasm, microtubule, stress fiber thyroid hormone receptor binding Human UniProtKB:Q8JZP9-1 GAS2L2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0007050=GO_REF:0000002, GO:0005856=GO_REF:0000039} Q8NHY3 GAS2-like protein 2 protein 20130413 {GO:0005737=IEA, GO:0007050=IEA, GO:0005856=IEA} cell cycle arrest cytoplasm, cytoskeleton Human UniProtKB-SubCell:SL-0090 GAS2L3 UniProtKB UniProtKB {GO:0008017=PMID:21561867, GO:0005737=GO_REF:0000039, GO:0030036=PMID:21561867, GO:0015630=PMID:21561867, GO:0005874=GO_REF:0000037, GO:0000226=PMID:21561867, GO:0003779=PMID:21561867, GO:0007050=GO_REF:0000002, GO:0015629=PMID:21561867} Q86XJ1 GAS2-like protein 3 protein 20121121 {GO:0008017=IDA, GO:0005737=IEA, GO:0030036=IDA, GO:0015630=IDA, GO:0005874=IEA, GO:0000226=IDA, GO:0003779=IDA, GO:0007050=IEA, GO:0015629=IDA} actin cytoskeleton organization, cell cycle arrest, microtubule cytoskeleton organization actin cytoskeleton, cytoplasm, microtubule, microtubule cytoskeleton actin binding, microtubule binding Human GAS6 Reactome UniProtKB {GO:0005515=PMID:18760998, GO:0006909=PMID:21501828, GO:0032715=PMID:19657094, GO:0050900=Reactome:REACT_12051, GO:0071307=PMID:16359517, GO:0005615=PMID:8336730, GO:2000510=PMID:19657094, GO:0060090=PMID:21501828, GO:0006508=Reactome:REACT_733, GO:0070374=PMID:15184064, GO:0048018=PMID:15184064, GO:0043027=PMID:16723520, GO:0005796=Reactome:REACT_1117, GO:0019064=PMID:21501828, GO:0005509=GO_REF:0000002, GO:0031589=GO_REF:0000019, GO:0043277=PMID:21501828, GO:0032720=PMID:19657094, GO:0030168=Reactome:REACT_798, GO:2000669=PMID:19657094, GO:0010804=PMID:19657094, GO:0010934=GO_REF:0000019, GO:0043491=PMID:16723520, GO:0070588=PMID:18395422, GO:0035754=PMID:19922767, GO:0001786=PMID:21501828, GO:0005788=Reactome:REACT_1, GO:0044267=Reactome:REACT_17015, GO:0040008=GO_REF:0000037, GO:0043687=Reactome:REACT_22161, GO:0051897=PMID:16723520, GO:0032008=GO_REF:0000024, GO:0008283=PMID:16564713, GO:0035457=PMID:19657094, GO:0031100=GO_REF:0000019, GO:2000533=GO_REF:0000024, GO:0048146=PMID:15184064, GO:0046718=PMID:21501828, GO:0097028=PMID:19657094, GO:0019079=PMID:21501828, GO:0085029=GO_REF:0000024, GO:0032148=GO_REF:0000024, GO:0031093=Reactome:REACT_21351, GO:0007050=PMID:16564713, GO:0007155=PMID:16564713, GO:0071333=GO_REF:0000024, GO:0043154=PMID:16723520, GO:0009267=GO_REF:0000019, GO:0030971=PMID:7634325, GO:0043066=PMID:19922767, GO:0005245=PMID:18395422, GO:0005102=PMID:7854420, GO:0070168=PMID:20048160, GO:0005576=Reactome:REACT_21351, GO:0003104=GO_REF:0000024, GO:0070527=PMID:16564713, GO:0007165=PMID:7854420, GO:0017187=Reactome:REACT_1132, GO:0016477=PMID:16564713, GO:0071363=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0001934=PMID:16723520, GO:0001764=GO_REF:0000019, GO:2000352=PMID:18760998, GO:0046813=PMID:21501828, GO:0097241=PMID:19922767, GO:0007167=GO_REF:0000019} Q14393 Growth arrest-specific protein 6 protein 20130301 {GO:0005515=IPI, GO:0006909=IDA, GO:0032715=IDA, GO:0050900=TAS, GO:0071307=IDA, GO:0005615=IDA, GO:2000510=IDA, GO:0060090=IDA, GO:0006508=TAS, GO:0070374=IDA, GO:0048018=IDA, GO:0043027=IDA, GO:0005796=TAS, GO:0019064=IDA, GO:0005509=IEA, GO:0031589=IEA, GO:0043277=IDA, GO:0032720=IDA, GO:0030168=TAS, GO:2000669=IDA, GO:0010804=IDA, GO:0010934=IEA, GO:0043491=IDA, GO:0070588=IDA, GO:0035754=IDA, GO:0001786=IDA, GO:0005788=TAS, GO:0044267=TAS, GO:0040008=IEA, GO:0043687=TAS, GO:0051897=IDA, GO:0032008=ISS, GO:0008283=TAS, GO:0035457=IDA, GO:0031100=IEA, GO:2000533=ISS, GO:0048146=IDA, GO:0046718=IDA, GO:0097028=IEP, GO:0019079=IDA, GO:0085029=ISS, GO:0032148=ISS, GO:0031093=TAS, GO:0007050=TAS, GO:0007155=TAS, GO:0071333=ISS, GO:0043154=IDA, GO:0009267=IEA, GO:0030971=IPI, GO:0043066=IDA, GO:0005245=IDA, GO:0005102=IPI, GO:0070168=IDA, GO:0005576=TAS, GO:0003104=ISS, GO:0070527=TAS, GO:0007165=IDA, GO:0017187=TAS, GO:0016477=TAS, GO:0071363=IEA, GO:0007596=TAS, GO:0002576=TAS, GO:0001934=IDA, GO:0001764=IEA, GO:2000352=IDA, GO:0046813=IDA, GO:0097241=IDA, GO:0007167=IEA} B cell chemotaxis, activation of protein kinase B activity, apoptotic cell clearance, blood coagulation, calcium ion transmembrane transport, cell adhesion, cell cycle arrest, cell migration, cell proliferation, cell-substrate adhesion, cellular protein metabolic process, cellular response to glucose stimulus, cellular response to growth factor stimulus, cellular response to interferon-alpha, cellular response to starvation, cellular response to vitamin K, dendritic cell differentiation, enzyme linked receptor protein signaling pathway, extracellular matrix assembly, hematopoietic stem cell migration to bone marrow, leukocyte migration, macrophage cytokine production, negative regulation of apoptotic process, negative regulation of biomineral tissue development, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of dendritic cell apoptotic process, negative regulation of endothelial cell apoptotic process, negative regulation of interleukin-6 production, negative regulation of renal albumin absorption, negative regulation of tumor necrosis factor production, negative regulation of tumor necrosis factor-mediated signaling pathway, neuron migration, organ regeneration, peptidyl-glutamic acid carboxylation, phagocytosis, platelet activation, platelet aggregation, platelet degranulation, positive regulation of ERK1 and ERK2 cascade, positive regulation of TOR signaling cascade, positive regulation of dendritic cell chemotaxis, positive regulation of fibroblast proliferation, positive regulation of glomerular filtration, positive regulation of protein kinase B signaling cascade, positive regulation of protein phosphorylation, post-translational protein modification, protein kinase B signaling cascade, proteolysis, regulation of growth, signal transduction, viral entry into host cell, viral entry into host cell via membrane fusion with the plasma membrane, viral genome replication, virion attachment, binding of host cell surface receptor Golgi lumen, endoplasmic reticulum lumen, extracellular region, extracellular space, platelet alpha granule lumen binding, bridging, calcium ion binding, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, phosphatidylserine binding, protein binding, receptor agonist activity, receptor binding, receptor tyrosine kinase binding, voltage-gated calcium channel activity Human GAS7 GOC UniProtKB {GO:0006355=PMID:9736752, GO:0005737=GO_REF:0000039, GO:0003700=PMID:9736752, GO:0051015=GO_REF:0000019, GO:0048812=GO_REF:0000019, GO:0008360=GO_REF:0000019, GO:0005884=GO_REF:0000019, GO:0030041=GO_REF:0000019, GO:0007050=PMID:9736752, GO:0051017=GO_REF:0000019, GO:0001726=GO_REF:0000019} O60861 Growth arrest-specific protein 7 protein 20130413 {GO:0006355=TAS, GO:0005737=IEA, GO:0003700=TAS, GO:0051015=IEA, GO:0048812=IEA, GO:0008360=IEA, GO:0005884=IEA, GO:0030041=IEA, GO:0007050=TAS, GO:0051017=IEA, GO:0001726=IEA} actin filament bundle assembly, actin filament polymerization, cell cycle arrest, neuron projection morphogenesis, regulation of cell shape, regulation of transcription, DNA-dependent actin filament, cytoplasm, ruffle actin filament binding, sequence-specific DNA binding transcription factor activity Human GAS8 PINC UniProtKB {GO:0003674=GO_REF:0000015, GO:0017137=GO_REF:0000019, GO:0008285=PMID:9790751, GO:0005794=GO_REF:0000039, GO:0031514=GO_REF:0000024, GO:0005874=PMID:10969087, GO:0005932=GO_REF:0000039, GO:0034613=GO_REF:0000019, GO:0030317=GO_REF:0000024} O95995 Growth arrest-specific protein 8 protein 20030904 {GO:0003674=ND, GO:0017137=IEA, GO:0008285=TAS, GO:0005794=IEA, GO:0031514=ISS, GO:0005874=IDA, GO:0005932=IEA, GO:0034613=IEA, GO:0030317=ISS} cellular protein localization, negative regulation of cell proliferation, sperm motility Golgi apparatus, microtubule, microtubule basal body, motile cilium Rab GTPase binding, molecular_function Human GAST Reactome UniProtKB {GO:0007165=PMID:7488110, GO:0007186=GO_REF:0000019, GO:0005179=GO_REF:0000019, GO:0005576=Reactome:REACT_121113} P01350 Gastrin protein 20100607 {GO:0007165=NAS, GO:0007186=IEA, GO:0005179=IEA, GO:0005576=TAS} G-protein coupled receptor signaling pathway, signal transduction extracellular region hormone activity Human GATA1 HPA UniProtKB {GO:0005515=PMID:11418466, GO:0097067=PMID:19375645, GO:0008285=GO_REF:0000019, GO:0003700=PMID:2467208, GO:0006366=PMID:2467208, GO:0071733=GO_REF:0000024, GO:0007267=GO_REF:0000019, GO:0050731=PMID:15701726, GO:0005634=GO_REF:0000052, GO:0097028=GO_REF:0000019, GO:2000678=PMID:15920471, GO:0002039=GO_REF:0000019, GO:0048821=PMID:10700180, GO:0045944=PMID:12200364, GO:0017053=PMID:15920471, GO:0001085=PMID:15920471, GO:0030222=PMID:8507862, GO:0033690=GO_REF:0000019, GO:0030221=PMID:7678994, GO:0035162=GO_REF:0000019, GO:0030220=PMID:10700180, GO:0005667=PMID:15920471, GO:0031965=GO_REF:0000052, GO:0043066=PMID:15967790, GO:0000976=PMID:10700180, GO:0010559=PMID:15701726, GO:0000977=PMID:2467208, GO:0008301=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0000978=GO_REF:0000019, GO:0030502=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0003677=PMID:11418466, GO:0010724=PMID:12200364, GO:0070527=PMID:15701726, GO:0043565=PMID:12200364, GO:0001078=PMID:15920471, GO:0001077=GO_REF:0000019, GO:0035854=PMID:12045236, GO:0007596=Reactome:REACT_604, GO:0030219=PMID:10700180, GO:0003682=GO_REF:0000019, GO:0030218=PMID:7678994, GO:0070742=PMID:12483298, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_25215, GO:0001158=GO_REF:0000019, GO:0008584=PMID:10700180} P15976 Erythroid transcription factor protein 20101115 {GO:0005515=IPI, GO:0097067=IDA, GO:0008285=IEA, GO:0003700=IDA, GO:0006366=IDA, GO:0071733=ISS, GO:0007267=IEA, GO:0050731=IMP, GO:0005634=IDA, GO:0097028=IEA, GO:2000678=IDA, GO:0002039=IEA, GO:0048821=IMP, GO:0045944=IDA, GO:0017053=IDA, GO:0001085=IPI, GO:0030222=IEP, GO:0033690=IEA, GO:0030221=IEP, GO:0035162=IEA, GO:0030220=IMP, GO:0005667=IDA, GO:0031965=IDA, GO:0043066=TAS, GO:0000976=IMP, GO:0010559=IMP, GO:0000977=IDA, GO:0008301=IEA, GO:0005730=IDA, GO:0000978=IEA, GO:0030502=IEA, GO:0001701=IEA, GO:0003677=IDA, GO:0010724=IDA, GO:0070527=IMP, GO:0043565=IMP, GO:0001078=IDA, GO:0001077=IEA, GO:0035854=IDA, GO:0007596=TAS, GO:0030219=IMP, GO:0003682=IEA, GO:0030218=IEP, GO:0070742=IPI, GO:0008270=IEA, GO:0005654=TAS, GO:0001158=IEA, GO:0008584=IMP} basophil differentiation, blood coagulation, cell-cell signaling, cellular response to thyroid hormone stimulus, dendritic cell differentiation, embryonic hemopoiesis, eosinophil differentiation, eosinophil fate commitment, erythrocyte development, erythrocyte differentiation, in utero embryonic development, male gonad development, megakaryocyte differentiation, negative regulation of apoptotic process, negative regulation of bone mineralization, negative regulation of cell proliferation, negative regulation of transcription regulatory region DNA binding, platelet aggregation, platelet formation, positive regulation of osteoblast proliferation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of transcription from RNA polymerase II promoter, regulation of definitive erythrocyte differentiation, regulation of glycoprotein biosynthetic process, transcription from RNA polymerase II promoter, transcriptional activation by promoter-enhancer looping nuclear membrane, nucleolus, nucleoplasm, nucleus, transcription factor complex, transcriptional repressor complex C2H2 zinc finger domain binding, DNA binding, DNA binding, bending, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II regulatory region sequence-specific DNA binding, RNA polymerase II transcription factor binding, chromatin binding, enhancer sequence-specific DNA binding, p53 binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding, zinc ion binding Human GATA2 HPA UniProtKB {GO:0005515=PMID:21988832, GO:0021514=GO_REF:0000019, GO:0006909=GO_REF:0000019, GO:0021533=GO_REF:0000019, GO:0003700=PMID:15016828, GO:0045599=PMID:20705609, GO:0021983=GO_REF:0000019, GO:0001655=GO_REF:0000019, GO:0070345=PMID:20705609, GO:0005634=GO_REF:0000052, GO:0035065=GO_REF:0000019, GO:0060872=GO_REF:0000019, GO:0050766=GO_REF:0000024, GO:0045654=GO_REF:0000019, GO:0048873=GO_REF:0000019, GO:0045944=PMID:15016828, GO:0048469=GO_REF:0000019, GO:0035019=GO_REF:0000019, GO:0045746=PMID:16672344, GO:2000178=PMID:16672344, GO:0042472=GO_REF:0000019, GO:0001709=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0021954=GO_REF:0000019, GO:0001892=GO_REF:0000019, GO:0060216=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0048663=GO_REF:0000019, GO:0045650=GO_REF:0000019, GO:0006351=PMID:16153155, GO:0045766=PMID:19242469, GO:0043234=GO_REF:0000019, GO:0001077=GO_REF:0000019, GO:0035854=PMID:12045236, GO:0007596=Reactome:REACT_604, GO:0045648=GO_REF:0000019, GO:0003682=PMID:19242469, GO:0070742=PMID:12483298, GO:0005654=Reactome:REACT_25215, GO:0008270=GO_REF:0000002, GO:0000980=GO_REF:0000019, GO:0001158=PMID:19323994, GO:0008134=PMID:15016828} P23769 Endothelial transcription factor GATA-2 protein 20111111 {GO:0005515=IPI, GO:0021514=IEA, GO:0006909=IEA, GO:0021533=IEA, GO:0003700=IDA, GO:0045599=IMP, GO:0021983=IEA, GO:0001655=IEA, GO:0070345=IMP, GO:0005634=IDA, GO:0035065=IEA, GO:0060872=IEA, GO:0050766=ISS, GO:0045654=IEA, GO:0048873=IEA, GO:0045944=IDA, GO:0048469=IEA, GO:0035019=IEA, GO:0045746=IDA, GO:2000178=IDA, GO:0042472=IEA, GO:0001709=IEA, GO:0005730=IDA, GO:0021954=IEA, GO:0001892=IEA, GO:0060216=IEA, GO:0000122=IEA, GO:0048663=IEA, GO:0045650=IEA, GO:0006351=IDA, GO:0045766=IDA, GO:0043234=IEA, GO:0001077=IEA, GO:0035854=IDA, GO:0007596=TAS, GO:0045648=IEA, GO:0003682=IDA, GO:0070742=IPI, GO:0005654=TAS, GO:0008270=IEA, GO:0000980=IEA, GO:0001158=IDA, GO:0008134=IPI} blood coagulation, cell differentiation in hindbrain, cell fate determination, cell maturation, central nervous system neuron development, definitive hemopoiesis, embryonic placenta development, eosinophil fate commitment, homeostasis of number of cells within a tissue, inner ear morphogenesis, negative regulation of Notch signaling pathway, negative regulation of fat cell differentiation, negative regulation of fat cell proliferation, negative regulation of macrophage differentiation, negative regulation of neural precursor cell proliferation, negative regulation of transcription from RNA polymerase II promoter, neuron fate commitment, phagocytosis, pituitary gland development, positive regulation of angiogenesis, positive regulation of erythrocyte differentiation, positive regulation of megakaryocyte differentiation, positive regulation of phagocytosis, positive regulation of transcription from RNA polymerase II promoter, regulation of histone acetylation, semicircular canal development, somatic stem cell maintenance, transcription, DNA-dependent, urogenital system development, ventral spinal cord interneuron differentiation nucleolus, nucleoplasm, nucleus, protein complex C2H2 zinc finger domain binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II distal enhancer sequence-specific DNA binding, chromatin binding, enhancer sequence-specific DNA binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, zinc ion binding NOT Human GATA3 BHF-UCL UniProtKB {GO:0071773=GO_REF:0000019, GO:0005515=PMID:19723756, GO:0032753=GO_REF:0000024, GO:0043627=PMID:10037815, GO:0003700=PMID:2050118, GO:0032754=GO_REF:0000019, GO:0044212=PMID:19735555, GO:2000146=PMID:20189993, GO:0009791=GO_REF:0000019, GO:0009653=PMID:10935639, GO:0072182=GO_REF:0000024, GO:0048589=GO_REF:0000019, GO:0048646=GO_REF:0000024, GO:0072179=GO_REF:0000024, GO:0072178=GO_REF:0000024, GO:0046983=GO_REF:0000019, GO:2000611=PMID:19248180, GO:0010332=GO_REF:0000019, GO:0031929=GO_REF:0000024, GO:0035799=GO_REF:0000019, GO:0042472=GO_REF:0000019, GO:0001709=GO_REF:0000024, GO:0003713=PMID:20484083, GO:0060231=PMID:20189993, GO:0072107=GO_REF:0000024, GO:0006952=PMID:7592673, GO:0001701=GO_REF:0000019, GO:0035898=GO_REF:0000019, GO:0001806=GO_REF:0000019, GO:0060037=GO_REF:0000024, GO:0010595=PMID:19674970, GO:0072643=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0008134=PMID:15016828, GO:0050852=GO_REF:0000024, GO:0060065=GO_REF:0000024, GO:2000679=PMID:20368097, GO:0045471=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0032736=GO_REF:0000019, GO:0002088=GO_REF:0000019, GO:0006959=GO_REF:0000019, GO:0048469=GO_REF:0000019, GO:0001046=PMID:19674970, GO:2000703=GO_REF:0000024, GO:0071599=GO_REF:0000019, GO:0001822=PMID:19248180, GO:0042493=GO_REF:0000019, GO:0001823=GO_REF:0000024, GO:0061085=GO_REF:0000019, GO:2000114=GO_REF:0000019, GO:2000683=PMID:19735555, GO:0009615=PMID:20583921, GO:0007596=Reactome:REACT_604, GO:0045064=GO_REF:0000019, GO:2000607=GO_REF:0000024, GO:0045061=GO_REF:0000019, GO:0050728=PMID:19674970, GO:0030218=GO_REF:0000019, GO:0042421=GO_REF:0000024, GO:0001764=GO_REF:0000019, GO:0000987=PMID:19232384, GO:0000790=PMID:20855495, GO:0006366=PMID:1871134, GO:0003180=GO_REF:0000024, GO:0045599=PMID:20705609, GO:0048538=GO_REF:0000019, GO:0003281=GO_REF:0000024, GO:0060676=GO_REF:0000024, GO:0043523=GO_REF:0000019, GO:0060374=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0071356=PMID:19674970, GO:0071353=PMID:20554961, GO:0032689=GO_REF:0000019, GO:2000664=PMID:20554961, GO:0000976=PMID:19723756, GO:2000667=PMID:20368097, GO:0070888=PMID:20855495, GO:0045786=PMID:20189993, GO:0072676=PMID:19805038, GO:0000979=GO_REF:0000019, GO:0014065=GO_REF:0000024, GO:0048485=GO_REF:0000024, GO:0002572=GO_REF:0000019, GO:0071837=PMID:18445004, GO:0005654=Reactome:REACT_25215, GO:0072602=GO_REF:0000019, GO:0045893=PMID:19723756, GO:0001158=GO_REF:0000019, GO:0045892=PMID:19674970, GO:0051897=PMID:19674970, GO:0008285=GO_REF:0000024, GO:0005134=GO_REF:0000019, GO:0035457=PMID:20554961, GO:0003215=GO_REF:0000024, GO:2000734=GO_REF:0000024, GO:0043583=PMID:19248180, GO:0045944=PMID:20855495, GO:0051569=GO_REF:0000019, GO:0035162=GO_REF:0000019, GO:0045582=GO_REF:0000024, GO:0032703=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0009967=PMID:19674970, GO:0003677=PMID:1871134, GO:0043370=GO_REF:0000019, GO:0042035=GO_REF:0000024, GO:0001078=PMID:19674970, GO:0007165=GO_REF:0000024, GO:0060017=GO_REF:0000019, GO:0001077=GO_REF:0000019, GO:0061290=GO_REF:0000024, GO:0001071=PMID:19674970, GO:2000352=PMID:19674970, GO:0033600=PMID:19483726, GO:0008584=GO_REF:0000024} P23771 Trans-acting T-cell-specific transcription factor GATA-3 protein 20110205 {GO:0071773=IEA, GO:0005515=IPI, GO:0032753=ISS, GO:0043627=IEP, GO:0003700=TAS, GO:0032754=IEA, GO:0044212=IDA, GO:2000146=IMP, GO:0009791=IEA, GO:0009653=TAS, GO:0072182=ISS, GO:0048589=IEA, GO:0048646=ISS, GO:0072179=ISS, GO:0072178=ISS, GO:0046983=IEA, GO:2000611=IMP, GO:0010332=IEA, GO:0031929=ISS, GO:0035799=IEA, GO:0042472=IEA, GO:0001709=ISS, GO:0003713=IDA, GO:0060231=IDA, GO:0072107=ISS, GO:0006952=TAS, GO:0001701=IEA, GO:0035898=IEA, GO:0001806=IEA, GO:0060037=ISS, GO:0010595=IMP, GO:0072643=IEA, GO:0008270=IEA, GO:0008134=IPI, GO:0050852=ISS, GO:0060065=ISS, GO:2000679=IMP, GO:0045471=IEA, GO:0005634=IDA, GO:0032736=IEA, GO:0002088=IEA, GO:0006959=IEA, GO:0048469=IEA, GO:0001046=IDA, GO:2000703=ISS, GO:0071599=IEA, GO:0001822=IMP, GO:0042493=IEA, GO:0001823=ISS, GO:0061085=IEA, GO:2000114=IEA, GO:2000683=IMP, GO:0009615=IEP, GO:0007596=TAS, GO:0045064=IEA, GO:2000607=ISS, GO:0045061=IEA, GO:0050728=IMP, GO:0030218=IEA, GO:0042421=ISS, GO:0001764=IEA, GO:0000987=IDA, GO:0000790=IDA, GO:0006366=TAS, GO:0003180=ISS, GO:0045599=IMP, GO:0048538=IEA, GO:0003281=ISS, GO:0060676=ISS, GO:0043523=IEA, GO:0060374=IEA, GO:0007411=IEA, GO:0071356=IEP, GO:0071353=IEP, GO:0032689=IEA, GO:2000664=IDA, GO:0000976=IDA, GO:2000667=IMP, GO:0070888=IDA, GO:0045786=IMP, GO:0072676=IDA, GO:0000979=IEA, GO:0014065=ISS, GO:0048485=ISS, GO:0002572=IEA, GO:0071837=IPI, GO:0005654=TAS, GO:0072602=IEA, GO:0045893=IDA, GO:0001158=IEA, GO:0045892=IMP, GO:0051897=IMP, GO:0008285=ISS, GO:0005134=IEA, GO:0035457=IEP, GO:0003215=ISS, GO:2000734=ISS, GO:0043583=IMP, GO:0045944=IMP, GO:0051569=IEA, GO:0035162=IEA, GO:0045582=ISS, GO:0032703=IEA, GO:0005730=IDA, GO:0009967=IMP, GO:0003677=TAS, GO:0043370=IEA, GO:0042035=ISS, GO:0001078=IMP, GO:0007165=ISS, GO:0060017=IEA, GO:0001077=IEA, GO:0061290=ISS, GO:0001071=IMP, GO:2000352=IMP, GO:0033600=IDA, GO:0008584=ISS} T cell receptor signaling pathway, T-helper 2 cell differentiation, TOR signaling cascade, anatomical structure formation involved in morphogenesis, anatomical structure morphogenesis, aortic valve morphogenesis, axon guidance, blood coagulation, canonical Wnt receptor signaling pathway involved in metanephric kidney development, cardiac right ventricle morphogenesis, cell fate determination, cell maturation, cellular response to BMP stimulus, cellular response to interferon-alpha, cellular response to interleukin-4, cellular response to tumor necrosis factor, defense response, developmental growth, ear development, embryonic hemopoiesis, erythrocyte differentiation, humoral immune response, in utero embryonic development, inner ear morphogenesis, interferon-gamma secretion, interleukin-4 secretion, kidney development, lens development in camera-type eye, lymphocyte migration, male gonad development, mast cell differentiation, mesenchymal to epithelial transition, mesonephros development, negative regulation of cell cycle, negative regulation of cell motility, negative regulation of cell proliferation, negative regulation of cell proliferation involved in mesonephros development, negative regulation of endothelial cell apoptotic process, negative regulation of fat cell differentiation, negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation, negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation, negative regulation of inflammatory response, negative regulation of interferon-gamma production, negative regulation of interleukin-2 production, negative regulation of mammary gland epithelial cell proliferation, negative regulation of transcription, DNA-dependent, nephric duct formation, nephric duct morphogenesis, neuron migration, norepinephrine biosynthetic process, otic vesicle development, parathyroid gland development, parathyroid hormone secretion, pharyngeal system development, phosphatidylinositol 3-kinase cascade, positive regulation of T cell differentiation, positive regulation of endothelial cell migration, positive regulation of interleukin-13 production, positive regulation of interleukin-13 secretion, positive regulation of interleukin-4 production, positive regulation of interleukin-5 production, positive regulation of interleukin-5 secretion, positive regulation of protein kinase B signaling cascade, positive regulation of signal transduction, positive regulation of thyroid hormone generation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription regulatory region DNA binding, positive regulation of transcription, DNA-dependent, positive regulation of ureteric bud formation, post-embryonic development, pro-T cell differentiation, regulation of CD4-positive, alpha-beta T cell differentiation, regulation of cellular response to X-ray, regulation of cytokine biosynthetic process, regulation of establishment of cell polarity, regulation of histone H3-K27 methylation, regulation of histone H3-K4 methylation, regulation of nephron tubule epithelial cell differentiation, regulation of neuron apoptotic process, response to drug, response to estrogen stimulus, response to ethanol, response to gamma radiation, response to virus, signal transduction, sympathetic nervous system development, thymic T cell selection, thymus development, transcription from RNA polymerase II promoter, type IV hypersensitivity, ureter maturation, ureteric bud formation, uterus development, ventricular septum development nuclear chromatin, nucleolus, nucleoplasm, nucleus DNA binding, E-box binding, HMG box domain binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II core promoter sequence-specific DNA binding, core promoter proximal region sequence-specific DNA binding, core promoter sequence-specific DNA binding, enhancer sequence-specific DNA binding, interleukin-2 receptor binding, nucleic acid binding transcription factor activity, protein binding, protein dimerization activity, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, transcription factor binding, transcription regulatory region DNA binding, transcription regulatory region sequence-specific DNA binding, zinc ion binding Human GATA4 BHF-UCL UniProtKB {GO:0060045=GO_REF:0000019, GO:0005515=PMID:9312027, GO:0003289=GO_REF:0000024, GO:0043627=GO_REF:0000019, GO:0003700=PMID:9312027, GO:0006366=GO_REF:0000024, GO:0044212=PMID:9566909, GO:0003181=GO_REF:0000019, GO:0003705=GO_REF:0000019, GO:0003281=GO_REF:0000024, GO:0007283=GO_REF:0000019, GO:0060575=PMID:9566909, GO:0001947=GO_REF:0000024, GO:0060008=GO_REF:0000019, GO:0061049=GO_REF:0000019, GO:0055007=PMID:9857019, GO:0003229=GO_REF:0000019, GO:0001706=GO_REF:0000019, GO:0000977=GO_REF:0000019, GO:0023019=GO_REF:0000019, GO:0030509=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0001702=GO_REF:0000019, GO:0072148=GO_REF:0000019, GO:0035239=GO_REF:0000019, GO:0010507=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_25215, GO:0045893=GO_REF:0000024, GO:0001158=GO_REF:0000019, GO:0008134=PMID:9858576, GO:0051525=GO_REF:0000019, GO:0007267=GO_REF:0000024, GO:0003215=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0051891=GO_REF:0000024, GO:0060395=GO_REF:0000019, GO:0071372=GO_REF:0000019, GO:0030513=GO_REF:0000019, GO:0045944=GO_REF:0000024, GO:0033613=GO_REF:0000024, GO:0071333=GO_REF:0000019, GO:0060070=GO_REF:0000019, GO:0006355=GO_REF:0000024, GO:0060413=PMID:12845333, GO:0003197=PMID:21330551, GO:0042493=PMID:20585342, GO:0070410=PMID:21330551, GO:0035054=GO_REF:0000024, GO:0003208=PMID:20347099, GO:0010575=GO_REF:0000024, GO:0003677=GO_REF:0000024, GO:0045766=GO_REF:0000024, GO:0003290=PMID:20347099, GO:0009612=GO_REF:0000019, GO:0043565=GO_REF:0000024, GO:0001076=PMID:21330551, GO:0007492=PMID:20347099, GO:0048557=GO_REF:0000019, GO:0060464=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0003682=GO_REF:0000019, GO:0072520=GO_REF:0000019, GO:0048617=GO_REF:0000024, GO:0008584=PMID:17848411} P43694 Transcription factor GATA-4 protein 20121129 {GO:0060045=IEA, GO:0005515=IPI, GO:0003289=ISS, GO:0043627=IEA, GO:0003700=IDA, GO:0006366=ISS, GO:0044212=IDA, GO:0003181=IEA, GO:0003705=IEA, GO:0003281=ISS, GO:0007283=IEA, GO:0060575=IDA, GO:0001947=ISS, GO:0060008=IEA, GO:0061049=IEA, GO:0055007=IEP, GO:0003229=IEA, GO:0001706=IEA, GO:0000977=IEA, GO:0023019=IEA, GO:0030509=IEA, GO:0001701=IEA, GO:0001702=IEA, GO:0072148=IEA, GO:0035239=IEA, GO:0010507=IEA, GO:0008270=IEA, GO:0005654=TAS, GO:0045893=ISS, GO:0001158=IEA, GO:0008134=IPI, GO:0051525=IEA, GO:0007267=ISS, GO:0003215=ISS, GO:0005634=ISS, GO:0051891=ISS, GO:0060395=IEA, GO:0071372=IEA, GO:0030513=IEA, GO:0045944=ISS, GO:0033613=ISS, GO:0071333=IEA, GO:0060070=IEA, GO:0006355=ISS, GO:0060413=IMP, GO:0003197=IMP, GO:0042493=IMP, GO:0070410=IPI, GO:0035054=ISS, GO:0003208=TAS, GO:0010575=ISS, GO:0003677=ISS, GO:0045766=ISS, GO:0003290=IMP, GO:0009612=IEA, GO:0043565=ISS, GO:0001076=IDA, GO:0007492=TAS, GO:0048557=IEA, GO:0060464=IEA, GO:0007596=TAS, GO:0003682=IEA, GO:0072520=IEA, GO:0048617=ISS, GO:0008584=IEP} BMP signaling pathway, SMAD protein signal transduction, Sertoli cell differentiation, atrial septum morphogenesis, atrial septum primum morphogenesis, atrial septum secundum morphogenesis, atrioventricular valve morphogenesis, blood coagulation, canonical Wnt receptor signaling pathway, cardiac muscle cell differentiation, cardiac right ventricle morphogenesis, cardiac ventricle morphogenesis, cell growth involved in cardiac muscle cell development, cell-cell signaling, cellular response to follicle-stimulating hormone stimulus, cellular response to glucose stimulus, embryonic digestive tract morphogenesis, embryonic foregut morphogenesis, embryonic heart tube anterior/posterior pattern specification, endocardial cushion development, endoderm development, endoderm formation, epithelial cell fate commitment, gastrulation with mouth forming second, heart looping, in utero embryonic development, intestinal epithelial cell differentiation, lung lobe formation, male gonad development, negative regulation of autophagy, positive regulation of BMP signaling pathway, positive regulation of angiogenesis, positive regulation of cardiac muscle cell proliferation, positive regulation of cardioblast differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation vascular endothelial growth factor production, regulation of transcription, DNA-dependent, response to drug, response to estrogen stimulus, response to mechanical stimulus, seminiferous tubule development, signal transduction involved in regulation of gene expression, spermatogenesis, transcription from RNA polymerase II promoter, tube morphogenesis, ventricular cardiac muscle tissue development, ventricular septum development nucleoplasm, nucleus DNA binding, NFAT protein binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, RNA polymerase II regulatory region sequence-specific DNA binding, RNA polymerase II transcription factor binding transcription factor activity, activating transcription factor binding, chromatin binding, co-SMAD binding, enhancer sequence-specific DNA binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding, zinc ion binding Human GATA5 Reactome UniProtKB {GO:0071773=GO_REF:0000019, GO:0003700=PMID:14986113, GO:0044212=PMID:9566909, GO:0007596=Reactome:REACT_604, GO:0045944=PMID:14986113, GO:0003705=GO_REF:0000019, GO:0005654=Reactome:REACT_25215, GO:0005634=PMID:9566909, GO:0008270=GO_REF:0000002, GO:0001158=GO_REF:0000019, GO:0060575=PMID:9566909} Q9BWX5 Transcription factor GATA-5 protein 20130301 {GO:0071773=IEA, GO:0003700=IDA, GO:0044212=IDA, GO:0007596=TAS, GO:0045944=IDA, GO:0003705=IEA, GO:0005654=TAS, GO:0005634=IDA, GO:0008270=IEA, GO:0001158=IEA, GO:0060575=IDA} blood coagulation, cellular response to BMP stimulus, intestinal epithelial cell differentiation, positive regulation of transcription from RNA polymerase II promoter nucleoplasm, nucleus RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, enhancer sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding, zinc ion binding Human GATA6 BHF-UCL UniProtKB {GO:0071773=GO_REF:0000019, GO:0060045=GO_REF:0000019, GO:0005515=PMID:16199874, GO:0043627=GO_REF:0000019, GO:0003700=PMID:19666519, GO:0044212=PMID:19666519, GO:0006366=PMID:19666519, GO:0003705=GO_REF:0000019, GO:0000981=PMID:21127043, GO:0003310=GO_REF:0000019, GO:0032911=PMID:21127043, GO:0032912=PMID:21127043, GO:0071158=PMID:9593712, GO:0060575=PMID:9566909, GO:0048645=GO_REF:0000019, GO:0060430=GO_REF:0000019, GO:0003309=GO_REF:0000019, GO:0055007=GO_REF:0000019, GO:0001103=GO_REF:0000019, GO:0019901=PMID:20864106, GO:0000122=PMID:18177748, GO:0070848=PMID:21127043, GO:0000979=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0001889=GO_REF:0000019, GO:0035239=GO_REF:0000019, GO:0060486=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_25215, GO:0006644=GO_REF:0000019, GO:0045892=PMID:18177748, GO:0051145=PMID:17626241, GO:0008134=PMID:15016828, GO:0005634=PMID:19666519, GO:0051891=GO_REF:0000019, GO:0071371=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0043066=PMID:21127043, GO:0042493=PMID:18671946, GO:0006915=GO_REF:0000019, GO:0071456=PMID:21127043, GO:0045766=PMID:21127043, GO:0007493=GO_REF:0000019, GO:0060947=PMID:11889139, GO:0007596=Reactome:REACT_604, GO:0003682=GO_REF:0000019, GO:0003148=PMID:19666519, GO:0060510=GO_REF:0000019, GO:0008584=PMID:17848411} Q92908 Transcription factor GATA-6 protein 20080306 {GO:0071773=IEA, GO:0060045=IEA, GO:0005515=IPI, GO:0043627=IEA, GO:0003700=IDA, GO:0044212=IDA, GO:0006366=IDA, GO:0003705=IEA, GO:0000981=IMP, GO:0003310=IEA, GO:0032911=IMP, GO:0032912=IMP, GO:0071158=IDA, GO:0060575=IDA, GO:0048645=IEA, GO:0060430=IEA, GO:0003309=IEA, GO:0055007=IEA, GO:0001103=IEA, GO:0019901=IPI, GO:0000122=IDA, GO:0070848=IDA, GO:0000979=IEA, GO:0001701=IEA, GO:0001889=IEA, GO:0035239=IEA, GO:0060486=IEA, GO:0008270=IEA, GO:0005654=TAS, GO:0006644=IEA, GO:0045892=IDA, GO:0051145=IMP, GO:0008134=IPI, GO:0005634=IDA, GO:0051891=IEA, GO:0071371=IEA, GO:0045944=IEA, GO:0005667=IEA, GO:0043066=IMP, GO:0042493=IMP, GO:0006915=IEA, GO:0071456=IDA, GO:0045766=IDA, GO:0007493=IEA, GO:0060947=IMP, GO:0007596=TAS, GO:0003682=IEA, GO:0003148=IMP, GO:0060510=IEA, GO:0008584=IEP} Clara cell differentiation, Type II pneumocyte differentiation, apoptotic process, blood coagulation, cardiac muscle cell differentiation, cardiac vascular smooth muscle cell differentiation, cellular response to BMP stimulus, cellular response to gonadotropin stimulus, cellular response to hypoxia, endodermal cell fate determination, in utero embryonic development, intestinal epithelial cell differentiation, liver development, lung saccule development, male gonad development, negative regulation of apoptotic process, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, negative regulation of transforming growth factor beta1 production, negative regulation of transforming growth factor beta2 production, organ formation, outflow tract septum morphogenesis, pancreatic A cell differentiation, phospholipid metabolic process, positive regulation of angiogenesis, positive regulation of cardiac muscle cell proliferation, positive regulation of cardioblast differentiation, positive regulation of cell cycle arrest, positive regulation of transcription from RNA polymerase II promoter, response to drug, response to estrogen stimulus, response to growth factor stimulus, smooth muscle cell differentiation, transcription from RNA polymerase II promoter, tube morphogenesis, type B pancreatic cell differentiation nucleoplasm, nucleus, transcription factor complex RNA polymerase II core promoter sequence-specific DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, RNA polymerase II repressing transcription factor binding, chromatin binding, protein binding, protein kinase binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding, zinc ion binding Human UniProtKB:Q03014 GATAD1 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0005634=PMID:21965549, GO:0008270=GO_REF:0000002} Q8WUU5 GATA zinc finger domain-containing protein 1 protein 20120821 {GO:0043565=IEA, GO:0003700=IEA, GO:0005634=IDA, GO:0008270=IEA} nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human GATAD2A HPA UniProtKB {GO:0005515=PMID:12183469, GO:0010172=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0001568=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0012501=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0001842=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0021506=GO_REF:0000019, GO:0006306=PMID:12183469, GO:0043565=GO_REF:0000002, GO:0016581=PMID:12183469, GO:0016607=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0030674=PMID:12183469, GO:0045892=PMID:12183469} Q86YP4 Transcriptional repressor p66-alpha protein 20080205 {GO:0005515=IPI, GO:0010172=IEA, GO:0003700=IEA, GO:0001568=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0012501=IEA, GO:0001701=IEA, GO:0001842=IEA, GO:0006351=IEA, GO:0021506=IEA, GO:0006306=TAS, GO:0043565=IEA, GO:0016581=IDA, GO:0016607=IEA, GO:0008270=IEA, GO:0030674=IDA, GO:0045892=IDA} DNA methylation, anterior neuropore closure, blood vessel development, embryonic body morphogenesis, in utero embryonic development, negative regulation of transcription, DNA-dependent, neural fold formation, programmed cell death, transcription, DNA-dependent NuRD complex, nuclear speck, nucleolus, nucleus protein binding, protein binding, bridging, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding NOT Human GATAD2B HPA UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0016607=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q8WXI9 Transcriptional repressor p66-beta protein 20090616 {GO:0043565=IEA, GO:0003700=IEA, GO:0016607=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0006351=IEA} transcription, DNA-dependent nuclear speck, nucleolus, nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding NOT Human GATC UniProtKB UniProtKB {GO:0005739=PMID:19805282, GO:0032543=PMID:19805282, GO:0050567=PMID:19805282, GO:0030956=PMID:19805282, GO:0070681=PMID:19805282, GO:0006450=GO_REF:0000002, GO:0005524=GO_REF:0000037} O43716 Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial protein 20110818 {GO:0005739=IDA, GO:0032543=IMP, GO:0050567=IDA, GO:0030956=IDA, GO:0070681=IDA, GO:0006450=IEA, GO:0005524=IEA} glutaminyl-tRNAGln biosynthesis via transamidation, mitochondrial translation, regulation of translational fidelity glutamyl-tRNA(Gln) amidotransferase complex, mitochondrion ATP binding, glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity Human GATM Reactome UniProtKB {GO:0015067=GO_REF:0000019, GO:0007584=GO_REF:0000019, GO:0016813=GO_REF:0000002, GO:0015068=Reactome:REACT_396, GO:0005743=GO_REF:0000039, GO:0043434=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0009790=GO_REF:0000019, GO:0042246=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0034641=Reactome:REACT_13, GO:0005758=Reactome:REACT_396, GO:0006601=PMID:9218780, GO:0006600=Reactome:REACT_813, GO:0006979=GO_REF:0000019, GO:0046689=GO_REF:0000019} P50440 Glycine amidinotransferase, mitochondrial protein 20130213 {GO:0015067=IEA, GO:0007584=IEA, GO:0016813=IEA, GO:0015068=TAS, GO:0005743=IEA, GO:0043434=IEA, GO:0044281=TAS, GO:0009790=IEA, GO:0042246=IEA, GO:0005739=IEA, GO:0034641=TAS, GO:0005758=TAS, GO:0006601=IDA, GO:0006600=TAS, GO:0006979=IEA, GO:0046689=IEA} cellular nitrogen compound metabolic process, creatine biosynthetic process, creatine metabolic process, embryo development, response to mercury ion, response to nutrient, response to oxidative stress, response to peptide hormone stimulus, small molecule metabolic process, tissue regeneration mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrion amidinotransferase activity, glycine amidinotransferase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines Human GATSL1 null null {} null null null null {} null null null GATSL2 null null {} null null null null {} null null null GBA BHF-UCL UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0008219=GO_REF:0000037, GO:0006687=Reactome:REACT_116105, GO:0005975=GO_REF:0000002, GO:0032715=PMID:19279008, GO:0035307=PMID:19279008, GO:0005102=PMID:18022370, GO:0004348=PMID:19279011, GO:0044281=Reactome:REACT_111217, GO:0005765=PMID:18022370, GO:0006680=PMID:19279011, GO:0050728=PMID:19279008, GO:0043407=PMID:19279008, GO:0071356=PMID:19279008, GO:0046513=PMID:19279011, GO:0023021=PMID:19279008, GO:0046512=PMID:19279011, GO:0043202=PMID:18022370} P04062 Glucosylceramidase protein 20110628 {GO:0006665=TAS, GO:0008219=IEA, GO:0006687=TAS, GO:0005975=IEA, GO:0032715=IDA, GO:0035307=IMP, GO:0005102=ISS, GO:0004348=IDA, GO:0044281=TAS, GO:0005765=ISS, GO:0006680=IMP, GO:0050728=IC, GO:0043407=IMP, GO:0071356=IMP, GO:0046513=IMP, GO:0023021=IMP, GO:0046512=IMP, GO:0043202=ISS} carbohydrate metabolic process, cell death, cellular response to tumor necrosis factor, ceramide biosynthetic process, glucosylceramide catabolic process, glycosphingolipid metabolic process, negative regulation of MAP kinase activity, negative regulation of inflammatory response, negative regulation of interleukin-6 production, positive regulation of protein dephosphorylation, small molecule metabolic process, sphingolipid metabolic process, sphingosine biosynthetic process, termination of signal transduction lysosomal lumen, lysosomal membrane glucosylceramidase activity, receptor binding Human UniProtKB:P17439 GBA2 Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0006687=Reactome:REACT_116105, GO:0005886=Reactome:REACT_115724, GO:0008206=PMID:17105727, GO:0016139=PMID:11489889, GO:0004348=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0016021=PMID:17105727, GO:0008422=PMID:11489889, GO:0005790=PMID:11489889, GO:0006680=GO_REF:0000002} Q9HCG7 Non-lysosomal glucosylceramidase protein 20130301 {GO:0006665=TAS, GO:0006687=TAS, GO:0005886=TAS, GO:0008206=IDA, GO:0016139=NAS, GO:0004348=IEA, GO:0044281=TAS, GO:0016021=IDA, GO:0008422=IDA, GO:0005790=TAS, GO:0006680=IEA} bile acid metabolic process, glucosylceramide catabolic process, glycoside catabolic process, glycosphingolipid metabolic process, small molecule metabolic process, sphingolipid metabolic process integral to membrane, plasma membrane, smooth endoplasmic reticulum beta-glucosidase activity, glucosylceramidase activity Human GBA3 Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0017042=PMID:17595169, GO:0004565=PMID:17595169, GO:0006687=Reactome:REACT_116105, GO:0046477=PMID:17595169, GO:0005975=GO_REF:0000002, GO:0016139=PMID:11389701, GO:0044281=Reactome:REACT_111217, GO:0008422=PMID:17595169, GO:0005829=Reactome:REACT_115663} Q9H227 Cytosolic beta-glucosidase protein 20130301 {GO:0006665=TAS, GO:0017042=IDA, GO:0004565=IDA, GO:0006687=TAS, GO:0046477=IMP, GO:0005975=IEA, GO:0016139=IDA, GO:0044281=TAS, GO:0008422=IDA, GO:0005829=TAS} carbohydrate metabolic process, glycoside catabolic process, glycosphingolipid metabolic process, glycosylceramide catabolic process, small molecule metabolic process, sphingolipid metabolic process cytosol beta-galactosidase activity, beta-glucosidase activity, glycosylceramidase activity Human GBAS BHF-UCL UniProtKB {GO:0005515=PMID:20562859, GO:0005739=GO_REF:0000054, GO:0006754=PMID:20888800, GO:2000984=PMID:20888800, GO:0016020=PMID:9615231, GO:0005887=PMID:9615231, GO:0006119=PMID:20888800} O75323 Protein NipSnap homolog 2 protein 20120716 {GO:0005515=IPI, GO:0005739=IDA, GO:0006754=IMP, GO:2000984=IMP, GO:0016020=TAS, GO:0005887=TAS, GO:0006119=IMP} ATP biosynthetic process, negative regulation of ATP citrate synthase activity, oxidative phosphorylation integral to plasma membrane, membrane, mitochondrion protein binding Human GBE1 Reactome UniProtKB {GO:0005975=Reactome:REACT_474, GO:0043169=GO_REF:0000002, GO:0005978=Reactome:REACT_1736, GO:0005977=PMID:8613547, GO:0006006=Reactome:REACT_723, GO:0044281=Reactome:REACT_111217, GO:0006091=PMID:8613547, GO:0004553=GO_REF:0000002, GO:0003844=GO_REF:0000003, GO:0005829=Reactome:REACT_1560} Q04446 1,4-alpha-glucan-branching enzyme protein 20130301 {GO:0005975=TAS, GO:0043169=IEA, GO:0005978=TAS, GO:0005977=TAS, GO:0006006=TAS, GO:0044281=TAS, GO:0006091=TAS, GO:0004553=IEA, GO:0003844=IEA, GO:0005829=TAS} carbohydrate metabolic process, generation of precursor metabolites and energy, glucose metabolic process, glycogen biosynthetic process, glycogen metabolic process, small molecule metabolic process cytosol 1,4-alpha-glucan branching enzyme activity, cation binding, hydrolase activity, hydrolyzing O-glycosyl compounds Human GBF1 HPA UniProtKB {GO:0005802=GO_REF:0000033, GO:0005801=GO_REF:0000019, GO:0005794=GO_REF:0000052, GO:0005795=GO_REF:0000019, GO:0006890=Reactome:REACT_11208, GO:0006892=Reactome:REACT_11235, GO:0048205=Reactome:REACT_11096, GO:0005739=GO_REF:0000019, GO:0005086=GO_REF:0000033, GO:0000139=Reactome:REACT_14808, GO:0032012=GO_REF:0000002, GO:0005788=GO_REF:0000019, GO:0016192=GO_REF:0000033, GO:0016044=Reactome:REACT_11123, GO:0005777=GO_REF:0000019} Q92538 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 protein 20111111 {GO:0005802=IBA, GO:0005801=IEA, GO:0005794=IDA, GO:0005795=IEA, GO:0006890=TAS, GO:0006892=TAS, GO:0048205=TAS, GO:0005739=IEA, GO:0005086=IBA, GO:0000139=TAS, GO:0032012=IEA, GO:0005788=IEA, GO:0016192=IBA, GO:0016044=TAS, GO:0005777=IEA} COPI coating of Golgi vesicle, cellular membrane organization, post-Golgi vesicle-mediated transport, regulation of ARF protein signal transduction, retrograde vesicle-mediated transport, Golgi to ER, vesicle-mediated transport Golgi apparatus, Golgi membrane, Golgi stack, cis-Golgi network, endoplasmic reticulum lumen, mitochondrion, peroxisome, trans-Golgi network ARF guanyl-nucleotide exchange factor activity Human GBP1 Reactome UniProtKB {GO:0051607=GO_REF:0000037, GO:0000139=GO_REF:0000039, GO:0019221=Reactome:REACT_25229, GO:0003924=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0005525=GO_REF:0000037, GO:0060333=Reactome:REACT_25078, GO:0005829=Reactome:REACT_25082} P32455 Interferon-induced guanylate-binding protein 1 protein 20130228 {GO:0051607=IEA, GO:0000139=IEA, GO:0019221=TAS, GO:0003924=IEA, GO:0005576=IEA, GO:0005525=IEA, GO:0060333=TAS, GO:0005829=TAS} cytokine-mediated signaling pathway, defense response to virus, interferon-gamma-mediated signaling pathway Golgi membrane, cytosol, extracellular region GTP binding, GTPase activity Human GBP2 Reactome UniProtKB {GO:0006955=PMID:1715024, GO:0060337=Reactome:REACT_25162, GO:0000139=GO_REF:0000039, GO:0019221=Reactome:REACT_25229, GO:0003924=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0005525=GO_REF:0000037, GO:0060333=Reactome:REACT_25078, GO:0005829=Reactome:REACT_25192} P32456 Interferon-induced guanylate-binding protein 2 protein 20130228 {GO:0006955=TAS, GO:0060337=TAS, GO:0000139=IEA, GO:0019221=TAS, GO:0003924=IEA, GO:0005634=IEA, GO:0005525=IEA, GO:0060333=TAS, GO:0005829=TAS} cytokine-mediated signaling pathway, immune response, interferon-gamma-mediated signaling pathway, type I interferon-mediated signaling pathway Golgi membrane, cytosol, nucleus GTP binding, GTPase activity Human GBP3 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0051607=GO_REF:0000037, GO:0016020=GO_REF:0000039, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q9H0R5 Guanylate-binding protein 3 protein 20130413 {GO:0005737=IEA, GO:0051607=IEA, GO:0016020=IEA, GO:0003924=IEA, GO:0005525=IEA} defense response to virus cytoplasm, membrane GTP binding, GTPase activity Human UniProtKB-SubCell:SL-0162 GBP5 UniProtKB UniProtKB {GO:0016020=GO_REF:0000039, GO:0071346=GO_REF:0000019, GO:0003924=GO_REF:0000002, GO:0031410=GO_REF:0000019, GO:0005525=GO_REF:0000037} Q96PP8 Guanylate-binding protein 5 protein 20130413 {GO:0016020=IEA, GO:0071346=IEA, GO:0003924=IEA, GO:0031410=IEA, GO:0005525=IEA} cellular response to interferon-gamma cytoplasmic vesicle, membrane GTP binding, GTPase activity Human UniProtKB-SubCell:SL-0162 GBP7 UniProtKB UniProtKB {GO:0016020=GO_REF:0000039, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q8N8V2 Guanylate-binding protein 7 protein 20130413 {GO:0016020=IEA, GO:0003924=IEA, GO:0005525=IEA} membrane GTP binding, GTPase activity Human UniProtKB-SubCell:SL-0162 GC Reactome UniProtKB {GO:0051180=PMID:1696927, GO:0042359=Reactome:REACT_13523, GO:0051183=GO_REF:0000002, GO:0005576=Reactome:REACT_13727, GO:0003779=PMID:12119014, GO:0005499=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0005615=GO_REF:0000002, GO:0008202=Reactome:REACT_11057, GO:0043202=Reactome:REACT_13664, GO:0005829=Reactome:REACT_13608} P02774 Vitamin D-binding protein protein 20100417 {GO:0051180=TAS, GO:0042359=TAS, GO:0051183=IEA, GO:0005576=TAS, GO:0003779=IPI, GO:0005499=IEA, GO:0044281=TAS, GO:0005615=IEA, GO:0008202=TAS, GO:0043202=TAS, GO:0005829=TAS} small molecule metabolic process, steroid metabolic process, vitamin D metabolic process, vitamin transport cytosol, extracellular region, extracellular space, lysosomal lumen actin binding, vitamin D binding, vitamin transporter activity Human GCA HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0006944=PMID:1530588, GO:0005886=GO_REF:0000052, GO:0005509=PMID:11717497, GO:0042803=PMID:11717497} P28676 Grancalcin protein 20101115 {GO:0005737=IDA, GO:0006944=TAS, GO:0005886=IDA, GO:0005509=IDA, GO:0042803=IPI} cellular membrane fusion cytoplasm, plasma membrane calcium ion binding, protein homodimerization activity Human GCAT UniProtKB UniProtKB {GO:0005739=GO_REF:0000029, GO:0006520=PMID:10712613, GO:0019518=GO_REF:0000041, GO:0009058=GO_REF:0000002, GO:0008890=PMID:10712613, GO:0030170=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003824=GO_REF:0000002} O75600 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial protein 20021104 {GO:0005739=NAS, GO:0006520=NAS, GO:0019518=IEA, GO:0009058=IEA, GO:0008890=NAS, GO:0030170=IEA, GO:0005634=IEA, GO:0003824=IEA} L-threonine catabolic process to glycine, biosynthetic process, cellular amino acid metabolic process mitochondrion, nucleus catalytic activity, glycine C-acetyltransferase activity, pyridoxal phosphate binding Human GCC1 HPA UniProtKB {GO:0005515=PMID:16189514, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0000139=GO_REF:0000039, GO:0000042=GO_REF:0000002} Q96CN9 GRIP and coiled-coil domain-containing protein 1 protein 20101115 {GO:0005515=IPI, GO:0005737=IDA, GO:0005794=IDA, GO:0005886=IDA, GO:0000139=IEA, GO:0000042=IEA} protein targeting to Golgi Golgi apparatus, Golgi membrane, cytoplasm, plasma membrane protein binding Human GCC2 HPA UniProtKB {GO:0005515=PMID:18243103, GO:0005802=PMID:16885419, GO:0005794=GO_REF:0000052, GO:0034453=PMID:17543864, GO:0043001=PMID:16885419, GO:0090161=PMID:16885419, GO:0005634=GO_REF:0000052, GO:0071955=PMID:17488291, GO:0042802=PMID:18243103, GO:0070861=PMID:17488291, GO:0005737=GO_REF:0000052, GO:0016020=GO_REF:0000037, GO:0034499=PMID:16885419, GO:0031023=PMID:17543864, GO:0034067=PMID:16885419, GO:0006622=PMID:16885419, GO:0042147=PMID:17488291, GO:0000042=GO_REF:0000002} Q8IWJ2 GRIP and coiled-coil domain-containing protein 2 protein 20110516 {GO:0005515=IPI, GO:0005802=IDA, GO:0005794=IDA, GO:0034453=IMP, GO:0043001=IMP, GO:0090161=IMP, GO:0005634=IDA, GO:0071955=IMP, GO:0042802=IPI, GO:0070861=IMP, GO:0005737=IDA, GO:0016020=IEA, GO:0034499=IMP, GO:0031023=IMP, GO:0034067=IMP, GO:0006622=IMP, GO:0042147=IMP, GO:0000042=IEA} Golgi ribbon formation, Golgi to plasma membrane protein transport, late endosome to Golgi transport, microtubule anchoring, microtubule organizing center organization, protein localization to Golgi apparatus, protein targeting to Golgi, protein targeting to lysosome, recycling endosome to Golgi transport, regulation of protein exit from endoplasmic reticulum, retrograde transport, endosome to Golgi Golgi apparatus, cytoplasm, membrane, nucleus, trans-Golgi network identical protein binding, protein binding Human GCDH Reactome UniProtKB {GO:0019395=GO_REF:0000019, GO:0050660=GO_REF:0000019, GO:0005743=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0004361=Reactome:REACT_1409, GO:0005739=PMID:8541831, GO:0034641=Reactome:REACT_13, GO:0005759=Reactome:REACT_1409, GO:0003995=GO_REF:0000002, GO:0046949=GO_REF:0000019, GO:0006554=Reactome:REACT_1298, GO:0000062=GO_REF:0000019, GO:0006568=GO_REF:0000041} Q92947 Glutaryl-CoA dehydrogenase, mitochondrial protein 20100212 {GO:0019395=IEA, GO:0050660=IEA, GO:0005743=IEA, GO:0044281=TAS, GO:0004361=EXP, GO:0005739=TAS, GO:0034641=TAS, GO:0005759=TAS, GO:0003995=IEA, GO:0046949=IEA, GO:0006554=TAS, GO:0000062=IEA, GO:0006568=IEA} cellular nitrogen compound metabolic process, fatty acid oxidation, fatty-acyl-CoA biosynthetic process, lysine catabolic process, small molecule metabolic process, tryptophan metabolic process mitochondrial inner membrane, mitochondrial matrix, mitochondrion acyl-CoA dehydrogenase activity, fatty-acyl-CoA binding, flavin adenine dinucleotide binding, glutaryl-CoA dehydrogenase activity Human GCFC2 UniProtKB UniProtKB {GO:0006355=PMID:10500253, GO:0003700=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0045892=PMID:10500253, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P16383 GC-rich sequence DNA-binding factor 2 protein 20091215 {GO:0006355=NAS, GO:0003700=IEA, GO:0005634=IEA, GO:0045892=NAS, GO:0003677=IEA, GO:0006351=IEA} negative regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity Human GCG Reactome UniProtKB {GO:0007631=PMID:8538742, GO:0005886=Reactome:REACT_22268, GO:0008283=PMID:10861272, GO:0030819=GO_REF:0000019, GO:0010737=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0090280=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0032092=GO_REF:0000019, GO:0033138=GO_REF:0000019, GO:0071377=Reactome:REACT_1665, GO:0045860=GO_REF:0000019, GO:0070374=GO_REF:0000019, GO:0010800=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0035774=GO_REF:0000019, GO:0005102=PMID:9990065, GO:0005576=Reactome:REACT_24006, GO:0007165=PMID:7929237, GO:0006112=Reactome:REACT_1505, GO:0005179=GO_REF:0000037, GO:0007186=PMID:9990065, GO:0050796=Reactome:REACT_23974, GO:0005788=Reactome:REACT_24009, GO:0044267=Reactome:REACT_17015, GO:0034774=Reactome:REACT_24006} P01275 Glucagon protein 20090220 {GO:0007631=TAS, GO:0005886=TAS, GO:0008283=TAS, GO:0030819=IEA, GO:0010737=IEA, GO:0044281=TAS, GO:0090280=IEA, GO:0005615=IEA, GO:0032092=IEA, GO:0033138=IEA, GO:0071377=TAS, GO:0045860=IEA, GO:0070374=IEA, GO:0010800=IEA, GO:0043066=IEA, GO:0035774=IEA, GO:0005102=TAS, GO:0005576=TAS, GO:0007165=TAS, GO:0006112=TAS, GO:0005179=IEA, GO:0007186=TAS, GO:0050796=TAS, GO:0005788=TAS, GO:0044267=TAS, GO:0034774=TAS} G-protein coupled receptor signaling pathway, cell proliferation, cellular protein metabolic process, cellular response to glucagon stimulus, energy reserve metabolic process, feeding behavior, negative regulation of apoptotic process, positive regulation of ERK1 and ERK2 cascade, positive regulation of cAMP biosynthetic process, positive regulation of calcium ion import, positive regulation of insulin secretion involved in cellular response to glucose stimulus, positive regulation of peptidyl-serine phosphorylation, positive regulation of peptidyl-threonine phosphorylation, positive regulation of protein binding, positive regulation of protein kinase activity, protein kinase A signaling cascade, regulation of insulin secretion, signal transduction, small molecule metabolic process endoplasmic reticulum lumen, extracellular region, extracellular space, plasma membrane, secretory granule lumen hormone activity, receptor binding Human GCGR Reactome UniProtKB {GO:0005886=Reactome:REACT_22436, GO:0007584=PMID:7773293, GO:0044281=Reactome:REACT_111217, GO:0006091=PMID:7773293, GO:0006887=GO_REF:0000019, GO:0004967=GO_REF:0000019, GO:0005085=Reactome:REACT_22110, GO:0006112=Reactome:REACT_1505, GO:0009755=GO_REF:0000019, GO:0071377=Reactome:REACT_1665, GO:0008217=PMID:8563746, GO:0007188=PMID:8144028, GO:0007189=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0017046=GO_REF:0000019, GO:0005768=GO_REF:0000019} P47871 Glucagon receptor protein 20090511 {GO:0005886=TAS, GO:0007584=TAS, GO:0044281=TAS, GO:0006091=TAS, GO:0006887=IEA, GO:0004967=IEA, GO:0005085=TAS, GO:0006112=TAS, GO:0009755=IEA, GO:0071377=TAS, GO:0008217=TAS, GO:0007188=TAS, GO:0007189=IEA, GO:0016021=IEA, GO:0017046=IEA, GO:0005768=IEA} adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, cellular response to glucagon stimulus, energy reserve metabolic process, exocytosis, generation of precursor metabolites and energy, hormone-mediated signaling pathway, regulation of blood pressure, response to nutrient, small molecule metabolic process endosome, integral to membrane, plasma membrane glucagon receptor activity, guanyl-nucleotide exchange factor activity, peptide hormone binding Human GCH1 HPA UniProtKB {GO:0005515=PMID:21988832, GO:0050662=GO_REF:0000019, GO:0014916=GO_REF:0000019, GO:0006729=PMID:9445252, GO:0050999=Reactome:REACT_12389, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0045776=GO_REF:0000019, GO:0051291=GO_REF:0000019, GO:0042803=PMID:1669853, GO:0005829=Reactome:REACT_111143, GO:0006809=PMID:9445252, GO:0042416=PMID:16338639, GO:0005737=GO_REF:0000052, GO:0042311=GO_REF:0000019, GO:0050884=PMID:7874165, GO:0032496=PMID:7678411, GO:0046654=GO_REF:0000002, GO:0046209=Reactome:REACT_12508, GO:0051260=PMID:11087823, GO:0034341=PMID:12607127, GO:0031965=GO_REF:0000052, GO:0005509=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0003934=PMID:7874165, GO:0006917=GO_REF:0000019, GO:0031410=PMID:3318829, GO:0005525=PMID:14717702, GO:0042559=PMID:2463916, GO:0035998=GO_REF:0000041, GO:0006184=PMID:2463916, GO:0043234=PMID:11087823, GO:0030742=GO_REF:0000019, GO:0051000=PMID:12176133, GO:0008217=PMID:17717598, GO:0008270=PMID:11087823, GO:0048265=GO_REF:0000024, GO:0034612=PMID:9445252} P30793 GTP cyclohydrolase 1 protein 20101115 {GO:0005515=IPI, GO:0050662=IEA, GO:0014916=IEA, GO:0006729=IDA, GO:0050999=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0045776=IEA, GO:0051291=IEA, GO:0042803=IPI, GO:0005829=TAS, GO:0006809=NAS, GO:0042416=IDA, GO:0005737=IDA, GO:0042311=IEA, GO:0050884=IMP, GO:0032496=IDA, GO:0046654=IEA, GO:0046209=TAS, GO:0051260=IDA, GO:0034341=IDA, GO:0031965=IDA, GO:0005509=IEA, GO:0005730=IDA, GO:0003934=IDA, GO:0006917=IEA, GO:0031410=IDA, GO:0005525=IDA, GO:0042559=IDA, GO:0035998=IEA, GO:0006184=IDA, GO:0043234=IDA, GO:0030742=IEA, GO:0051000=IDA, GO:0008217=IMP, GO:0008270=IDA, GO:0048265=ISS, GO:0034612=IDA} 7,8-dihydroneopterin 3'-triphosphate biosynthetic process, GTP catabolic process, dopamine biosynthetic process, induction of apoptosis, negative regulation of blood pressure, neuromuscular process controlling posture, nitric oxide biosynthetic process, nitric oxide metabolic process, positive regulation of nitric-oxide synthase activity, protein heterooligomerization, protein homooligomerization, pteridine-containing compound biosynthetic process, regulation of blood pressure, regulation of lung blood pressure, regulation of nitric-oxide synthase activity, response to interferon-gamma, response to lipopolysaccharide, response to pain, response to tumor necrosis factor, small molecule metabolic process, tetrahydrobiopterin biosynthetic process, tetrahydrofolate biosynthetic process, vasodilation cytoplasm, cytoplasmic vesicle, cytosol, nuclear membrane, nucleolus, nucleus, protein complex GTP binding, GTP cyclohydrolase I activity, GTP-dependent protein binding, calcium ion binding, coenzyme binding, protein binding, protein homodimerization activity, zinc ion binding Human GCHFR Reactome UniProtKB {GO:0005515=PMID:9092499, GO:0004857=GO_REF:0000019, GO:0042470=PMID:16778797, GO:0031965=PMID:16778797, GO:0050999=Reactome:REACT_12389, GO:0005634=PMID:16778797, GO:0044281=Reactome:REACT_111217, GO:0051291=GO_REF:0000019, GO:0030425=PMID:16778797, GO:0005829=Reactome:REACT_111115, GO:0006809=PMID:8702680, GO:0009890=GO_REF:0000002, GO:0043234=GO_REF:0000019, GO:0005737=PMID:16778797, GO:0030742=GO_REF:0000019, GO:0016787=GO_REF:0000038, GO:0046209=Reactome:REACT_12508, GO:0043105=GO_REF:0000019, GO:0016597=GO_REF:0000019, GO:0042133=PMID:8702680, GO:0044549=GO_REF:0000019} P30047 GTP cyclohydrolase 1 feedback regulatory protein protein 20110804 {GO:0005515=IPI, GO:0004857=IEA, GO:0042470=IDA, GO:0031965=IDA, GO:0050999=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0051291=IEA, GO:0030425=IDA, GO:0005829=TAS, GO:0006809=TAS, GO:0009890=IEA, GO:0043234=IEA, GO:0005737=IDA, GO:0030742=IEA, GO:0016787=IEA, GO:0046209=TAS, GO:0043105=IEA, GO:0016597=IEA, GO:0042133=TAS, GO:0044549=IEA} negative regulation of GTP cyclohydrolase I activity, negative regulation of biosynthetic process, neurotransmitter metabolic process, nitric oxide biosynthetic process, nitric oxide metabolic process, protein heterooligomerization, regulation of nitric-oxide synthase activity, small molecule metabolic process cytoplasm, cytosol, dendrite, melanosome, nuclear membrane, nucleus, protein complex GTP cyclohydrolase binding, GTP-dependent protein binding, amino acid binding, enzyme inhibitor activity, hydrolase activity, protein binding Human GCK BHF-UCL UniProtKB {GO:0005515=PMID:11522786, GO:0032811=GO_REF:0000019, GO:0001678=GO_REF:0000033, GO:0044281=Reactome:REACT_111217, GO:0004396=GO_REF:0000002, GO:0043266=GO_REF:0000019, GO:0007204=GO_REF:0000019, GO:0005536=PMID:12941786, GO:0006096=GO_REF:0000019, GO:0008645=Reactome:REACT_9441, GO:0005829=Reactome:REACT_6938, GO:0005739=GO_REF:0000019, GO:0008865=GO_REF:0000033, GO:0015758=Reactome:REACT_212, GO:0016301=GO_REF:0000038, GO:0044320=GO_REF:0000024, GO:0016773=GO_REF:0000002, GO:0032024=PMID:8878425, GO:0042149=GO_REF:0000019, GO:0006003=GO_REF:0000019, GO:0030141=GO_REF:0000019, GO:0045821=GO_REF:0000019, GO:0019158=GO_REF:0000033, GO:0045721=PMID:8878425, GO:0032869=GO_REF:0000024, GO:0000287=GO_REF:0000019, GO:0045725=PMID:8878425, GO:0005975=Reactome:REACT_474, GO:0019903=GO_REF:0000019, GO:0005978=GO_REF:0000019, GO:0006739=GO_REF:0000019, GO:0042593=PMID:20668700, GO:0055085=Reactome:REACT_19118, GO:0005524=PMID:12941786, GO:0010827=Reactome:REACT_6804, GO:0006110=PMID:9570959, GO:0004340=PMID:12941786, GO:0070509=GO_REF:0000019, GO:0051594=PMID:12941786, GO:0050796=PMID:20668700, GO:0043531=GO_REF:0000019, GO:0044448=GO_REF:0000019, GO:0031018=Reactome:REACT_13819, GO:0019932=GO_REF:0000019, GO:0005654=Reactome:REACT_6938, GO:0042327=GO_REF:0000019} P35557 Glucokinase protein 20100929 {GO:0005515=IPI, GO:0032811=IEA, GO:0001678=IBA, GO:0044281=TAS, GO:0004396=IEA, GO:0043266=IEA, GO:0007204=IEA, GO:0005536=IDA, GO:0006096=IEA, GO:0008645=TAS, GO:0005829=TAS, GO:0005739=IEA, GO:0008865=IBA, GO:0015758=TAS, GO:0016301=IEA, GO:0044320=ISS, GO:0016773=IEA, GO:0032024=IMP, GO:0042149=IEA, GO:0006003=IEA, GO:0030141=IEA, GO:0045821=IEA, GO:0019158=IBA, GO:0045721=IMP, GO:0032869=ISS, GO:0000287=IEA, GO:0045725=IMP, GO:0005975=TAS, GO:0019903=IEA, GO:0005978=IEA, GO:0006739=IEA, GO:0042593=IMP, GO:0055085=TAS, GO:0005524=IDA, GO:0010827=TAS, GO:0006110=NAS, GO:0004340=IDA, GO:0070509=IEA, GO:0051594=IMP, GO:0050796=IMP, GO:0043531=IEA, GO:0044448=IEA, GO:0031018=TAS, GO:0019932=IEA, GO:0005654=TAS, GO:0042327=IEA} NADP metabolic process, calcium ion import, carbohydrate metabolic process, cellular glucose homeostasis, cellular response to glucose starvation, cellular response to insulin stimulus, cellular response to leptin stimulus, detection of glucose, elevation of cytosolic calcium ion concentration, endocrine pancreas development, fructose 2,6-bisphosphate metabolic process, glucose homeostasis, glucose transport, glycogen biosynthetic process, glycolysis, hexose transport, negative regulation of epinephrine secretion, negative regulation of gluconeogenesis, positive regulation of glycogen biosynthetic process, positive regulation of glycolysis, positive regulation of insulin secretion, positive regulation of phosphorylation, regulation of glucose transport, regulation of glycolysis, regulation of insulin secretion, regulation of potassium ion transport, second-messenger-mediated signaling, small molecule metabolic process, transmembrane transport cell cortex part, cytosol, mitochondrion, nucleoplasm, secretory granule ADP binding, ATP binding, fructokinase activity, glucokinase activity, glucose binding, hexokinase activity, kinase activity, magnesium ion binding, mannokinase activity, phosphotransferase activity, alcohol group as acceptor, protein binding, protein phosphatase binding Human UniProtKB:P17712 GCKR BHF-UCL UniProtKB {GO:0005515=PMID:11522786, GO:0004857=GO_REF:0000019, GO:0001678=GO_REF:0000019, GO:0005975=Reactome:REACT_474, GO:0070095=PMID:14627435, GO:0019904=GO_REF:0000019, GO:0070328=PMID:19526250, GO:0033133=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0033132=PMID:14627435, GO:0046415=PMID:19503597, GO:0055085=Reactome:REACT_19118, GO:0010827=Reactome:REACT_6804, GO:0008645=Reactome:REACT_9441, GO:0005829=Reactome:REACT_6938, GO:0005739=GO_REF:0000019, GO:0015758=Reactome:REACT_212, GO:0016301=GO_REF:0000038, GO:0009750=PMID:14627435, GO:0030246=GO_REF:0000019, GO:0005654=Reactome:REACT_6938, GO:0019899=GO_REF:0000019, GO:0000060=GO_REF:0000024} Q14397 Glucokinase regulatory protein protein 20100929 {GO:0005515=IPI, GO:0004857=IEA, GO:0001678=IEA, GO:0005975=TAS, GO:0070095=IDA, GO:0019904=IEA, GO:0070328=IMP, GO:0033133=IEA, GO:0005634=IEA, GO:0044281=TAS, GO:0033132=IDA, GO:0046415=IMP, GO:0055085=TAS, GO:0010827=TAS, GO:0008645=TAS, GO:0005829=TAS, GO:0005739=IEA, GO:0015758=TAS, GO:0016301=IEA, GO:0009750=IDA, GO:0030246=IEA, GO:0005654=TAS, GO:0019899=IEA, GO:0000060=ISS} carbohydrate metabolic process, cellular glucose homeostasis, glucose transport, hexose transport, negative regulation of glucokinase activity, positive regulation of glucokinase activity, protein import into nucleus, translocation, regulation of glucose transport, response to fructose stimulus, small molecule metabolic process, transmembrane transport, triglyceride homeostasis, urate metabolic process cytosol, mitochondrion, nucleoplasm, nucleus carbohydrate binding, enzyme binding, enzyme inhibitor activity, fructose-6-phosphate binding, kinase activity, protein binding, protein domain specific binding Human GCLC Reactome UniProtKB {GO:0050662=PMID:9841880, GO:0046685=GO_REF:0000019, GO:0006805=Reactome:REACT_13433, GO:0009408=PMID:8104187, GO:0006534=PMID:2294991, GO:0032436=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0051409=GO_REF:0000019, GO:0005829=Reactome:REACT_6970, GO:0034641=Reactome:REACT_13, GO:0043524=GO_REF:0000019, GO:0005737=GO_REF:0000033, GO:0050880=PMID:12598062, GO:0051900=GO_REF:0000019, GO:0004357=PMID:16183645, GO:0006750=Reactome:REACT_6960, GO:0031397=GO_REF:0000019, GO:0009725=PMID:8104187, GO:0009410=GO_REF:0000019, GO:0006979=PMID:10395918, GO:0043066=PMID:10439045, GO:0000287=PMID:24639, GO:0046982=GO_REF:0000019, GO:0006536=PMID:12663448, GO:0005524=GO_REF:0000037, GO:0019852=GO_REF:0000019, GO:0000096=Reactome:REACT_115639, GO:0043531=PMID:24639, GO:0017109=GO_REF:0000019, GO:0045454=PMID:10439045, GO:0016595=PMID:9841880, GO:0045892=PMID:10439045} P48506 Glutamate--cysteine ligase catalytic subunit protein 20130213 {GO:0050662=IPI, GO:0046685=IEA, GO:0006805=TAS, GO:0009408=IDA, GO:0006534=IDA, GO:0032436=IEA, GO:0044281=TAS, GO:0051409=IEA, GO:0005829=TAS, GO:0034641=TAS, GO:0043524=IEA, GO:0005737=IBA, GO:0050880=IMP, GO:0051900=IEA, GO:0004357=IMP, GO:0006750=TAS, GO:0031397=IEA, GO:0009725=IDA, GO:0009410=IEA, GO:0006979=IDA, GO:0043066=IDA, GO:0000287=IDA, GO:0046982=IEA, GO:0006536=IDA, GO:0005524=IEA, GO:0019852=IEA, GO:0000096=TAS, GO:0043531=IDA, GO:0017109=IEA, GO:0045454=IDA, GO:0016595=IDA, GO:0045892=IDA} L-ascorbic acid metabolic process, cell redox homeostasis, cellular nitrogen compound metabolic process, cysteine metabolic process, glutamate metabolic process, glutathione biosynthetic process, negative regulation of apoptotic process, negative regulation of neuron apoptotic process, negative regulation of protein ubiquitination, negative regulation of transcription, DNA-dependent, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, regulation of blood vessel size, regulation of mitochondrial depolarization, response to arsenic-containing substance, response to heat, response to hormone stimulus, response to nitrosative stress, response to oxidative stress, response to xenobiotic stimulus, small molecule metabolic process, sulfur amino acid metabolic process, xenobiotic metabolic process cytoplasm, cytosol, glutamate-cysteine ligase complex ADP binding, ATP binding, coenzyme binding, glutamate binding, glutamate-cysteine ligase activity, magnesium ion binding, protein heterodimerization activity Human GCLM Reactome UniProtKB {GO:0006805=Reactome:REACT_13433, GO:0046982=GO_REF:0000019, GO:0006536=PMID:9841880, GO:0006534=GO_REF:0000019, GO:0042493=PMID:9895302, GO:0044281=Reactome:REACT_111217, GO:0051409=GO_REF:0000019, GO:0005829=Reactome:REACT_6970, GO:0034641=Reactome:REACT_13, GO:0043524=GO_REF:0000019, GO:0035226=PMID:9841880, GO:0050880=PMID:12975258, GO:0051900=GO_REF:0000019, GO:0000096=Reactome:REACT_115639, GO:0035229=GO_REF:0000019, GO:0004357=PMID:16183645, GO:0006750=Reactome:REACT_6960, GO:0017109=GO_REF:0000019, GO:0006979=PMID:10395918} P48507 Glutamate--cysteine ligase regulatory subunit protein 20130213 {GO:0006805=TAS, GO:0046982=IEA, GO:0006536=IDA, GO:0006534=IEA, GO:0042493=IDA, GO:0044281=TAS, GO:0051409=IEA, GO:0005829=TAS, GO:0034641=TAS, GO:0043524=IEA, GO:0035226=IPI, GO:0050880=IMP, GO:0051900=IEA, GO:0000096=TAS, GO:0035229=IEA, GO:0004357=IMP, GO:0006750=TAS, GO:0017109=IEA, GO:0006979=IDA} cellular nitrogen compound metabolic process, cysteine metabolic process, glutamate metabolic process, glutathione biosynthetic process, negative regulation of neuron apoptotic process, positive regulation of glutamate-cysteine ligase activity, regulation of blood vessel size, regulation of mitochondrial depolarization, response to drug, response to nitrosative stress, response to oxidative stress, small molecule metabolic process, sulfur amino acid metabolic process, xenobiotic metabolic process cytosol, glutamate-cysteine ligase complex glutamate-cysteine ligase activity, glutamate-cysteine ligase catalytic subunit binding, protein heterodimerization activity Human GCM1 PINC UniProtKB {GO:0005667=PMID:15385555, GO:0006355=PMID:15385555, GO:0003700=PMID:15385555, GO:0060018=GO_REF:0000019, GO:0060706=GO_REF:0000019, GO:0060670=GO_REF:0000019, GO:0005634=PMID:8962155, GO:0008270=GO_REF:0000019, GO:0009653=PMID:8962155, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0008134=PMID:15385555} Q9NP62 Chorion-specific transcription factor GCMa protein 20050308 {GO:0005667=IDA, GO:0006355=IDA, GO:0003700=IDA, GO:0060018=IEA, GO:0060706=IEA, GO:0060670=IEA, GO:0005634=TAS, GO:0008270=IEA, GO:0009653=TAS, GO:0003677=IEA, GO:0006351=IEA, GO:0008134=IPI} anatomical structure morphogenesis, astrocyte fate commitment, branching involved in labyrinthine layer morphogenesis, cell differentiation involved in embryonic placenta development, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus, transcription factor complex DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, zinc ion binding Human GCN1L1 GOC UniProtKB {GO:0005737=GO_REF:0000052, GO:0005840=PMID:9234705, GO:0006412=PMID:9234705, GO:0008135=PMID:9234705, GO:0006417=GO_REF:0000037} Q92616 Translational activator GCN1 protein 20130413 {GO:0005737=IDA, GO:0005840=NAS, GO:0006412=NAS, GO:0008135=NAS, GO:0006417=IEA} regulation of translation, translation cytoplasm, ribosome translation factor activity, nucleic acid binding Human GCNT1 Reactome UniProtKB {GO:0032868=GO_REF:0000019, GO:0003829=GO_REF:0000003, GO:0000139=Reactome:REACT_115905, GO:0006493=PMID:1329093, GO:0060993=GO_REF:0000019, GO:0048729=GO_REF:0000019, GO:0016266=Reactome:REACT_115606, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0005615=GO_REF:0000019, GO:0043687=Reactome:REACT_22161} Q02742 Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase protein 20130301 {GO:0032868=IEA, GO:0003829=IEA, GO:0000139=TAS, GO:0006493=TAS, GO:0060993=IEA, GO:0048729=IEA, GO:0016266=TAS, GO:0016021=IEA, GO:0044267=TAS, GO:0005615=IEA, GO:0043687=TAS} O-glycan processing, cellular protein metabolic process, kidney morphogenesis, post-translational protein modification, protein O-linked glycosylation, response to insulin stimulus, tissue morphogenesis Golgi membrane, extracellular space, integral to membrane beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity Human GCNT3 Reactome UniProtKB {GO:0003829=GO_REF:0000003, GO:0005975=PMID:9988682, GO:0002426=GO_REF:0000019, GO:0016266=Reactome:REACT_115606, GO:0008109=GO_REF:0000003, GO:0050892=GO_REF:0000019, GO:0016020=PMID:9988682, GO:0006493=PMID:9988682, GO:0000139=Reactome:REACT_115905, GO:0060993=GO_REF:0000019, GO:0048729=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0047225=GO_REF:0000019, GO:0043687=Reactome:REACT_22161} O95395 Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 protein 20130301 {GO:0003829=IEA, GO:0005975=NAS, GO:0002426=IEA, GO:0016266=TAS, GO:0008109=IEA, GO:0050892=IEA, GO:0016020=TAS, GO:0006493=TAS, GO:0000139=TAS, GO:0060993=IEA, GO:0048729=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0047225=IEA, GO:0043687=TAS} O-glycan processing, carbohydrate metabolic process, cellular protein metabolic process, immunoglobulin production in mucosal tissue, intestinal absorption, kidney morphogenesis, post-translational protein modification, protein O-linked glycosylation, tissue morphogenesis Golgi membrane, integral to membrane, membrane N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity, acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity, beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity Human GCSH PINC UniProtKB {GO:0005739=GO_REF:0000039, GO:0005960=GO_REF:0000002, GO:0019464=GO_REF:0000019, GO:0004047=GO_REF:0000019, GO:0006546=PMID:1671321, GO:0019899=GO_REF:0000019} P23434 Glycine cleavage system H protein, mitochondrial protein 20030904 {GO:0005739=IEA, GO:0005960=IEA, GO:0019464=IEA, GO:0004047=IEA, GO:0006546=TAS, GO:0019899=IEA} glycine catabolic process, glycine decarboxylation via glycine cleavage system glycine cleavage complex, mitochondrion aminomethyltransferase activity, enzyme binding Human GDA Reactome UniProtKB {GO:0005622=PMID:10542258, GO:0006147=GO_REF:0000041, GO:0006195=Reactome:REACT_2086, GO:0006139=PMID:10075721, GO:0006144=Reactome:REACT_522, GO:0008892=Reactome:REACT_1442, GO:0055086=Reactome:REACT_1698, GO:0008270=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_1442, GO:0007399=PMID:10542258} Q9Y2T3 Guanine deaminase protein 20130213 {GO:0005622=TAS, GO:0006147=IEA, GO:0006195=TAS, GO:0006139=TAS, GO:0006144=TAS, GO:0008892=EXP, GO:0055086=TAS, GO:0008270=IEA, GO:0044281=TAS, GO:0005829=TAS, GO:0007399=TAS} guanine catabolic process, nervous system development, nucleobase-containing compound metabolic process, nucleobase-containing small molecule metabolic process, purine nucleobase metabolic process, purine nucleotide catabolic process, small molecule metabolic process cytosol, intracellular guanine deaminase activity, zinc ion binding Human GDAP1 UniProtKB UniProtKB {GO:0000266=PMID:15772096, GO:0006626=PMID:15772096, GO:0031307=PMID:15772096, GO:0032526=GO_REF:0000019} Q8TB36 Ganglioside-induced differentiation-associated protein 1 protein 20120608 {GO:0000266=IDA, GO:0006626=IMP, GO:0031307=IDA, GO:0032526=IEA} mitochondrial fission, protein targeting to mitochondrion, response to retinoic acid integral to mitochondrial outer membrane Human GDAP1L1 null null {} null null null null {} null null null GDAP2 ENSEMBL UniProtKB {GO:0032526=GO_REF:0000019} Q9NXN4 Ganglioside-induced differentiation-associated protein 2 protein 20130413 {GO:0032526=IEA} response to retinoic acid Human Ensembl:ENSMUSP00000029459 GDE1 UniProtKB UniProtKB {GO:0006629=PMID:10760272, GO:0005737=GO_REF:0000039, GO:0008081=GO_REF:0000002, GO:0047395=GO_REF:0000003, GO:0016021=PMID:10760272, GO:0008889=PMID:10760272, GO:0006071=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q9NZC3 Glycerophosphodiester phosphodiesterase 1 protein 20010824 {GO:0006629=TAS, GO:0005737=IEA, GO:0008081=IEA, GO:0047395=IEA, GO:0016021=TAS, GO:0008889=TAS, GO:0006071=IEA, GO:0046872=IEA} glycerol metabolic process, lipid metabolic process cytoplasm, integral to membrane glycerophosphodiester phosphodiesterase activity, glycerophosphoinositol glycerophosphodiesterase activity, metal ion binding, phosphoric diester hydrolase activity Human GDF10 UniProtKB UniProtKB {GO:0001501=PMID:8670277, GO:0005576=GO_REF:0000038, GO:0007179=PMID:8679252, GO:0008083=GO_REF:0000038, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037, GO:0040007=GO_REF:0000002} Q8N6T2 GDF10 protein protein 20130413 {GO:0001501=TAS, GO:0005576=IEA, GO:0007179=TAS, GO:0008083=IEA, GO:0005615=IEA, GO:0005125=IEA, GO:0040007=IEA} growth, skeletal system development, transforming growth factor beta receptor signaling pathway extracellular region, extracellular space cytokine activity, growth factor activity Human UniProtKB-KW:KW-0339 GDF11 UniProtKB UniProtKB {GO:0001656=GO_REF:0000019, GO:0001657=GO_REF:0000019, GO:0021512=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0005576=GO_REF:0000038, GO:0005575=GO_REF:0000015, GO:0048593=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0005125=GO_REF:0000029, GO:0007399=PMID:10075854, GO:0001501=PMID:10391213, GO:0031016=GO_REF:0000019, GO:0007498=PMID:10075854, GO:0048469=GO_REF:0000019, GO:0045596=GO_REF:0000019, GO:0040007=GO_REF:0000002, GO:0008083=GO_REF:0000037} O95390 Growth/differentiation factor 11 protein 20061026 {GO:0001656=IEA, GO:0001657=IEA, GO:0021512=IEA, GO:0008285=IEA, GO:0005576=IEA, GO:0005575=ND, GO:0048593=IEA, GO:0005615=IEA, GO:0005125=NAS, GO:0007399=TAS, GO:0001501=TAS, GO:0031016=IEA, GO:0007498=TAS, GO:0048469=IEA, GO:0045596=IEA, GO:0040007=IEA, GO:0008083=IEA} camera-type eye morphogenesis, cell maturation, growth, mesoderm development, metanephros development, negative regulation of cell differentiation, negative regulation of cell proliferation, nervous system development, pancreas development, skeletal system development, spinal cord anterior/posterior patterning, ureteric bud development cellular_component, extracellular region, extracellular space cytokine activity, growth factor activity Human GDF15 PINC UniProtKB {GO:0007165=PMID:9326641, GO:0007267=PMID:9326641, GO:0007179=PMID:9348093, GO:0005576=PMID:9326641, GO:0008083=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037} Q99988 Growth/differentiation factor 15 protein 20030904 {GO:0007165=TAS, GO:0007267=TAS, GO:0007179=TAS, GO:0005576=TAS, GO:0008083=IEA, GO:0005615=IEA, GO:0005125=IEA} cell-cell signaling, signal transduction, transforming growth factor beta receptor signaling pathway extracellular region, extracellular space cytokine activity, growth factor activity Human GDF2 BHF-UCL UniProtKB {GO:0005515=PMID:17068149, GO:0030308=PMID:17068149, GO:0051216=PMID:20406889, GO:0048514=PMID:20406889, GO:0005615=GO_REF:0000037, GO:0032757=PMID:19366699, GO:0006879=PMID:20406889, GO:0030513=GO_REF:0000019, GO:0001569=PMID:20406889, GO:0010862=PMID:17068149, GO:0030509=PMID:17068149, GO:0032924=PMID:17068149, GO:0005125=GO_REF:0000037, GO:0001649=GO_REF:0000019, GO:0045766=PMID:20406889, GO:0045669=GO_REF:0000019, GO:0010596=PMID:17068149, GO:0001503=PMID:20406889, GO:0001938=PMID:20406889, GO:0001937=PMID:20406889, GO:0016525=PMID:20406889, GO:0060389=PMID:17068149, GO:0008156=PMID:20406889, GO:0045893=PMID:17068149, GO:0008083=GO_REF:0000037, GO:0040007=GO_REF:0000002, GO:0045603=GO_REF:0000019, GO:0001570=GO_REF:0000019, GO:0043537=PMID:20406889} Q9UK05 Growth/differentiation factor 2 protein 20120314 {GO:0005515=IPI, GO:0030308=IDA, GO:0051216=TAS, GO:0048514=IDA, GO:0005615=IEA, GO:0032757=IDA, GO:0006879=TAS, GO:0030513=IEA, GO:0001569=IDA, GO:0010862=IDA, GO:0030509=IDA, GO:0032924=IDA, GO:0005125=IEA, GO:0001649=IEA, GO:0045766=IDA, GO:0045669=IEA, GO:0010596=IDA, GO:0001503=TAS, GO:0001938=IDA, GO:0001937=IDA, GO:0016525=TAS, GO:0060389=IDA, GO:0008156=TAS, GO:0045893=IDA, GO:0008083=IEA, GO:0040007=IEA, GO:0045603=IEA, GO:0001570=IEA, GO:0043537=TAS} BMP signaling pathway, activin receptor signaling pathway, blood vessel morphogenesis, cartilage development, cellular iron ion homeostasis, growth, negative regulation of DNA replication, negative regulation of angiogenesis, negative regulation of blood vessel endothelial cell migration, negative regulation of cell growth, negative regulation of endothelial cell migration, negative regulation of endothelial cell proliferation, ossification, osteoblast differentiation, pathway-restricted SMAD protein phosphorylation, patterning of blood vessels, positive regulation of BMP signaling pathway, positive regulation of angiogenesis, positive regulation of endothelial cell differentiation, positive regulation of endothelial cell proliferation, positive regulation of interleukin-8 production, positive regulation of osteoblast differentiation, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of transcription, DNA-dependent, vasculogenesis extracellular space cytokine activity, growth factor activity, protein binding Human GDF5 Reactome UniProtKB {GO:0035137=GO_REF:0000019, GO:0035136=GO_REF:0000019, GO:0051216=GO_REF:0000037, GO:0007267=PMID:8589725, GO:0005576=Reactome:REACT_150165, GO:0042981=GO_REF:0000019, GO:0030326=GO_REF:0000019, GO:0005125=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0030198=Reactome:REACT_118779, GO:0040014=GO_REF:0000019, GO:0032332=GO_REF:0000019, GO:0007179=PMID:7961761, GO:0040007=GO_REF:0000002, GO:0008083=GO_REF:0000037} P43026 Growth/differentiation factor 5 protein 20130301 {GO:0035137=IEA, GO:0035136=IEA, GO:0051216=IEA, GO:0007267=TAS, GO:0005576=TAS, GO:0042981=IEA, GO:0030326=IEA, GO:0005125=IEA, GO:0005615=IEA, GO:0030198=TAS, GO:0040014=IEA, GO:0032332=IEA, GO:0007179=TAS, GO:0040007=IEA, GO:0008083=IEA} cartilage development, cell-cell signaling, embryonic limb morphogenesis, extracellular matrix organization, forelimb morphogenesis, growth, hindlimb morphogenesis, positive regulation of chondrocyte differentiation, regulation of apoptotic process, regulation of multicellular organism growth, transforming growth factor beta receptor signaling pathway extracellular region, extracellular space cytokine activity, growth factor activity Human GDF6 BHF-UCL UniProtKB {GO:0045666=GO_REF:0000019, GO:0010862=PMID:16049014, GO:0060389=PMID:16049014, GO:0030509=PMID:16049014, GO:0045893=PMID:16049014, GO:0032924=PMID:16049014, GO:0008083=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037, GO:0040007=GO_REF:0000002, GO:0042803=GO_REF:0000019} Q6KF10 Growth/differentiation factor 6 protein 20090114 {GO:0045666=IEA, GO:0010862=IDA, GO:0060389=IDA, GO:0030509=IDA, GO:0045893=IDA, GO:0032924=IDA, GO:0008083=IEA, GO:0005615=IEA, GO:0005125=IEA, GO:0040007=IEA, GO:0042803=IEA} BMP signaling pathway, activin receptor signaling pathway, growth, pathway-restricted SMAD protein phosphorylation, positive regulation of neuron differentiation, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of transcription, DNA-dependent extracellular space cytokine activity, growth factor activity, protein homodimerization activity Human GDF7 BHF-UCL UniProtKB {GO:0005515=PMID:16049014, GO:0010862=PMID:16049014, GO:0021509=GO_REF:0000019, GO:0030509=PMID:16049014, GO:0060571=GO_REF:0000019, GO:0032924=PMID:16049014, GO:0005125=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0048853=GO_REF:0000019, GO:0021527=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0048608=GO_REF:0000019, GO:0045165=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0045666=GO_REF:0000019, GO:0030855=GO_REF:0000019, GO:2001051=GO_REF:0000019, GO:0030901=GO_REF:0000019, GO:0060389=PMID:16049014, GO:0048754=GO_REF:0000019, GO:0022612=GO_REF:0000019, GO:0045893=PMID:16049014, GO:0040007=GO_REF:0000002, GO:0008083=GO_REF:0000037} Q7Z4P5 Growth/differentiation factor 7 protein 20090114 {GO:0005515=IPI, GO:0010862=IDA, GO:0021509=IEA, GO:0030509=IDA, GO:0060571=IEA, GO:0032924=IDA, GO:0005125=IEA, GO:0005615=IEA, GO:0048853=IEA, GO:0021527=IEA, GO:0042803=IEA, GO:0048608=IEA, GO:0045165=IEA, GO:0007411=IEA, GO:0045666=IEA, GO:0030855=IEA, GO:2001051=IEA, GO:0030901=IEA, GO:0060389=IDA, GO:0048754=IEA, GO:0022612=IEA, GO:0045893=IDA, GO:0040007=IEA, GO:0008083=IEA} BMP signaling pathway, activin receptor signaling pathway, axon guidance, branching morphogenesis of an epithelial tube, cell fate commitment, epithelial cell differentiation, forebrain morphogenesis, gland morphogenesis, growth, midbrain development, morphogenesis of an epithelial fold, pathway-restricted SMAD protein phosphorylation, positive regulation of neuron differentiation, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of tendon cell differentiation, positive regulation of transcription, DNA-dependent, reproductive structure development, roof plate formation, spinal cord association neuron differentiation extracellular space cytokine activity, growth factor activity, protein binding, protein homodimerization activity Human GDF9 PINC UniProtKB {GO:0008284=PMID:19366876, GO:0030308=GO_REF:0000019, GO:2000870=PMID:20660033, GO:0007179=PMID:7760846, GO:0001555=GO_REF:0000019, GO:0007292=PMID:8849725, GO:0008083=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037} O60383 Growth/differentiation factor 9 protein 20030904 {GO:0008284=IDA, GO:0030308=IEA, GO:2000870=IMP, GO:0007179=TAS, GO:0001555=IEA, GO:0007292=TAS, GO:0008083=IEA, GO:0005615=IEA, GO:0005125=IEA} female gamete generation, negative regulation of cell growth, oocyte growth, positive regulation of cell proliferation, regulation of progesterone secretion, transforming growth factor beta receptor signaling pathway extracellular space cytokine activity, growth factor activity Human GDI1 IntAct UniProtKB {GO:0005515=PMID:19570034, GO:0051056=Reactome:REACT_11051, GO:0043005=GO_REF:0000019, GO:0017137=GO_REF:0000019, GO:0007264=Reactome:REACT_11044, GO:0030496=PMID:15166316, GO:0015031=GO_REF:0000002, GO:0005829=Reactome:REACT_10055, GO:0043234=GO_REF:0000019, GO:0051592=GO_REF:0000019, GO:0007165=PMID:7543319, GO:0005737=GO_REF:0000054, GO:0005093=GO_REF:0000019, GO:0050771=GO_REF:0000024, GO:0005092=PMID:7849400, GO:0005096=GO_REF:0000037} P31150 Rab GDP dissociation inhibitor alpha protein 20130415 {GO:0005515=IPI, GO:0051056=TAS, GO:0043005=IEA, GO:0017137=IEA, GO:0007264=TAS, GO:0030496=IDA, GO:0015031=IEA, GO:0005829=TAS, GO:0043234=IEA, GO:0051592=IEA, GO:0007165=TAS, GO:0005737=IDA, GO:0005093=IEA, GO:0050771=ISS, GO:0005092=TAS, GO:0005096=IEA} negative regulation of axonogenesis, protein transport, regulation of small GTPase mediated signal transduction, response to calcium ion, signal transduction, small GTPase mediated signal transduction cytoplasm, cytosol, midbody, neuron projection, protein complex GDP-dissociation inhibitor activity, GTPase activator activity, Rab GDP-dissociation inhibitor activity, Rab GTPase binding, protein binding Human UniProtKB:P61027 GDI2 InterPro UniProtKB {GO:0005515=PMID:19570034, GO:0051056=Reactome:REACT_11051, GO:0007165=PMID:16130169, GO:0005737=PMID:16130169, GO:0005794=GO_REF:0000019, GO:0009986=PMID:12493773, GO:0016020=GO_REF:0000039, GO:0007264=Reactome:REACT_11044, GO:0005093=GO_REF:0000002, GO:0015031=GO_REF:0000002, GO:0005097=GO_REF:0000019, GO:0005829=Reactome:REACT_10055} Q5SX91 Rab GDP dissociation inhibitor beta protein 20130413 {GO:0005515=IPI, GO:0051056=TAS, GO:0007165=TAS, GO:0005737=TAS, GO:0005794=IEA, GO:0009986=IDA, GO:0016020=IEA, GO:0007264=TAS, GO:0005093=IEA, GO:0015031=IEA, GO:0005097=IEA, GO:0005829=TAS} protein transport, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction Golgi apparatus, cell surface, cytoplasm, cytosol, membrane Rab GDP-dissociation inhibitor activity, Rab GTPase activator activity, protein binding Human InterPro:IPR000806 GDNF BHF-UCL UniProtKB {GO:0001656=GO_REF:0000024, GO:0008344=PMID:12358785, GO:0001658=GO_REF:0000024, GO:0001755=PMID:15242795, GO:0001759=GO_REF:0000019, GO:0060676=GO_REF:0000019, GO:0042803=PMID:8988018, GO:0031175=PMID:15242795, GO:0051584=PMID:8493557, GO:0043524=PMID:8493557, GO:0007411=Reactome:REACT_18266, GO:0045944=PMID:12358785, GO:0001941=GO_REF:0000019, GO:0048255=PMID:12358785, GO:0090190=PMID:17229286, GO:0043066=PMID:7830769, GO:0005102=PMID:10829012, GO:0072107=PMID:8657307, GO:0005576=PMID:9811930, GO:0060688=GO_REF:0000024, GO:0030432=GO_REF:0000024, GO:0048485=GO_REF:0000024, GO:0072108=GO_REF:0000019, GO:0048484=GO_REF:0000024, GO:0007399=PMID:8637574, GO:0021784=GO_REF:0000024, GO:0007165=PMID:7830769, GO:0003337=GO_REF:0000019, GO:0032770=PMID:12358785, GO:0008083=GO_REF:0000029, GO:0033603=PMID:12358785} P39905 Glial cell line-derived neurotrophic factor protein 20080926 {GO:0001656=ISS, GO:0008344=TAS, GO:0001658=ISS, GO:0001755=IDA, GO:0001759=IEA, GO:0060676=IEA, GO:0042803=IDA, GO:0031175=IDA, GO:0051584=IDA, GO:0043524=IDA, GO:0007411=TAS, GO:0045944=IDA, GO:0001941=IEA, GO:0048255=IDA, GO:0090190=IDA, GO:0043066=TAS, GO:0005102=TAS, GO:0072107=IDA, GO:0005576=IDA, GO:0060688=ISS, GO:0030432=ISS, GO:0048485=ISS, GO:0072108=IEA, GO:0048484=ISS, GO:0007399=TAS, GO:0021784=ISS, GO:0007165=TAS, GO:0003337=IEA, GO:0032770=IDA, GO:0008083=NAS, GO:0033603=TAS} adult locomotory behavior, axon guidance, branching involved in ureteric bud morphogenesis, enteric nervous system development, mRNA stabilization, mesenchymal to epithelial transition involved in metanephros morphogenesis, metanephros development, negative regulation of apoptotic process, negative regulation of neuron apoptotic process, nervous system development, neural crest cell migration, neuron projection development, organ induction, peristalsis, positive regulation of branching involved in ureteric bud morphogenesis, positive regulation of dopamine secretion, positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis, positive regulation of monooxygenase activity, positive regulation of transcription from RNA polymerase II promoter, positive regulation of ureteric bud formation, postganglionic parasympathetic nervous system development, postsynaptic membrane organization, regulation of dopamine uptake involved in synaptic transmission, regulation of morphogenesis of a branching structure, signal transduction, sympathetic nervous system development, ureteric bud formation extracellular region growth factor activity, protein homodimerization activity, receptor binding Human GDPD1 UniProtKB UniProtKB {GO:0006629=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0008889=GO_REF:0000002, GO:0006071=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q8N9F7 Glycerophosphodiester phosphodiesterase domain-containing protein 1 protein 20130413 {GO:0006629=IEA, GO:0005737=IEA, GO:0016021=IEA, GO:0008889=IEA, GO:0006071=IEA, GO:0046872=IEA} glycerol metabolic process, lipid metabolic process cytoplasm, integral to membrane glycerophosphodiester phosphodiesterase activity, metal ion binding Human UniProtKB-SubCell:SL-0086 GDPD2 HPA UniProtKB {GO:0006629=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000039, GO:0047394=GO_REF:0000003, GO:0016021=GO_REF:0000037, GO:0005856=GO_REF:0000039, GO:0008889=GO_REF:0000002, GO:0006071=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q9HCC8 Glycerophosphoinositol inositolphosphodiesterase GDPD2 protein 20111111 {GO:0006629=IEA, GO:0005737=IDA, GO:0005886=IEA, GO:0047394=IEA, GO:0016021=IEA, GO:0005856=IEA, GO:0008889=IEA, GO:0006071=IEA, GO:0046872=IEA} glycerol metabolic process, lipid metabolic process cytoplasm, cytoskeleton, integral to membrane, plasma membrane glycerophosphodiester phosphodiesterase activity, glycerophosphoinositol inositolphosphodiesterase activity, metal ion binding Human GDPD3 UniProtKB UniProtKB {GO:0006629=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0008889=GO_REF:0000002, GO:0006071=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q7L5L3 Glycerophosphodiester phosphodiesterase domain-containing protein 3 protein 20130413 {GO:0006629=IEA, GO:0016021=IEA, GO:0008889=IEA, GO:0006071=IEA, GO:0046872=IEA} glycerol metabolic process, lipid metabolic process integral to membrane glycerophosphodiester phosphodiesterase activity, metal ion binding Human UniProtKB-KW:KW-0479 GEM BHF-UCL UniProtKB {GO:0005515=PMID:19060904, GO:0007165=PMID:8825643, GO:0005516=GO_REF:0000037, GO:0006955=PMID:7912851, GO:0000287=PMID:17107948, GO:0007264=GO_REF:0000002, GO:0003924=PMID:17107948, GO:0009898=PMID:7912851, GO:0005634=GO_REF:0000019, GO:0005525=PMID:17107948, GO:0019003=PMID:17107948, GO:0007166=PMID:7912851} P55040 GTP-binding protein GEM protein 20090331 {GO:0005515=IPI, GO:0007165=TAS, GO:0005516=IEA, GO:0006955=TAS, GO:0000287=IDA, GO:0007264=IEA, GO:0003924=IDA, GO:0009898=IDA, GO:0005634=IEA, GO:0005525=IDA, GO:0019003=IDA, GO:0007166=TAS} cell surface receptor signaling pathway, immune response, signal transduction, small GTPase mediated signal transduction internal side of plasma membrane, nucleus GDP binding, GTP binding, GTPase activity, calmodulin binding, magnesium ion binding, protein binding Human GEMIN2 IntAct UniProtKB {GO:0008380=PMID:9323129, GO:0005515=PMID:21816274, GO:0006397=PMID:9323130, GO:0000245=GO_REF:0000002, GO:0010467=Reactome:REACT_71, GO:0015030=GO_REF:0000039, GO:0016070=Reactome:REACT_21257, GO:0005634=PMID:9323130, GO:0034660=Reactome:REACT_11052, GO:0000387=Reactome:REACT_11066, GO:0005829=Reactome:REACT_10041, GO:0005737=PMID:9323130, GO:0000375=PMID:9323129, GO:0005681=GO_REF:0000037, GO:0005654=Reactome:REACT_10010} O14893 Gem-associated protein 2 protein 20130415 {GO:0008380=TAS, GO:0005515=IPI, GO:0006397=TAS, GO:0000245=IEA, GO:0010467=TAS, GO:0015030=IEA, GO:0016070=TAS, GO:0005634=TAS, GO:0034660=TAS, GO:0000387=TAS, GO:0005829=TAS, GO:0005737=TAS, GO:0000375=TAS, GO:0005681=IEA, GO:0005654=TAS} RNA metabolic process, RNA splicing, RNA splicing, via transesterification reactions, gene expression, mRNA processing, ncRNA metabolic process, spliceosomal complex assembly, spliceosomal snRNP assembly Cajal body, cytoplasm, cytosol, nucleoplasm, nucleus, spliceosomal complex protein binding Human UniProtKB:Q16637 GEMIN4 Reactome UniProtKB {GO:0005515=PMID:12869526, GO:0010467=Reactome:REACT_71, GO:0015030=GO_REF:0000039, GO:0016070=Reactome:REACT_21257, GO:0006364=PMID:10725331, GO:0005730=GO_REF:0000039, GO:0034660=Reactome:REACT_11052, GO:0000387=Reactome:REACT_11066, GO:0005829=Reactome:REACT_10041, GO:0005737=PMID:10725331, GO:0030532=PMID:10725331, GO:0005681=GO_REF:0000037, GO:0005654=Reactome:REACT_10010} P57678 Gem-associated protein 4 protein 20130213 {GO:0005515=IPI, GO:0010467=TAS, GO:0015030=IEA, GO:0016070=TAS, GO:0006364=TAS, GO:0005730=IEA, GO:0034660=TAS, GO:0000387=TAS, GO:0005829=TAS, GO:0005737=TAS, GO:0030532=TAS, GO:0005681=IEA, GO:0005654=TAS} RNA metabolic process, gene expression, ncRNA metabolic process, rRNA processing, spliceosomal snRNP assembly Cajal body, cytoplasm, cytosol, nucleolus, nucleoplasm, small nuclear ribonucleoprotein complex, spliceosomal complex protein binding Human GEMIN5 HPA UniProtKB {GO:0005515=PMID:11714716, GO:0010467=Reactome:REACT_71, GO:0015030=GO_REF:0000039, GO:0016070=Reactome:REACT_21257, GO:0005634=GO_REF:0000052, GO:0034660=Reactome:REACT_11052, GO:0000387=Reactome:REACT_11066, GO:0005829=Reactome:REACT_10041, GO:0016604=PMID:11714716, GO:0005737=GO_REF:0000052, GO:0006461=PMID:11714716, GO:0000398=PMID:11714716, GO:0017069=PMID:16857593, GO:0005681=GO_REF:0000037, GO:0005654=Reactome:REACT_10010} Q8TEQ6 Gem-associated protein 5 protein 20110516 {GO:0005515=IPI, GO:0010467=TAS, GO:0015030=IEA, GO:0016070=TAS, GO:0005634=IDA, GO:0034660=TAS, GO:0000387=TAS, GO:0005829=TAS, GO:0016604=IDA, GO:0005737=IDA, GO:0006461=TAS, GO:0000398=TAS, GO:0017069=IDA, GO:0005681=IEA, GO:0005654=TAS} RNA metabolic process, gene expression, mRNA splicing, via spliceosome, ncRNA metabolic process, protein complex assembly, spliceosomal snRNP assembly Cajal body, cytoplasm, cytosol, nuclear body, nucleoplasm, nucleus, spliceosomal complex protein binding, snRNA binding Human GEMIN6 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0000245=GO_REF:0000002, GO:0010467=Reactome:REACT_71, GO:0015030=GO_REF:0000039, GO:0016070=Reactome:REACT_21257, GO:0005634=GO_REF:0000002, GO:0034660=Reactome:REACT_11052, GO:0000387=Reactome:REACT_11066, GO:0005829=Reactome:REACT_10041, GO:0016604=PMID:11748230, GO:0005737=PMID:11748230, GO:0000398=PMID:11748230, GO:0005681=GO_REF:0000037, GO:0005654=Reactome:REACT_10010} Q8WXD5 Gem-associated protein 6 protein 20130415 {GO:0005515=IPI, GO:0000245=IEA, GO:0010467=TAS, GO:0015030=IEA, GO:0016070=TAS, GO:0005634=IEA, GO:0034660=TAS, GO:0000387=TAS, GO:0005829=TAS, GO:0016604=IDA, GO:0005737=IDA, GO:0000398=TAS, GO:0005681=IEA, GO:0005654=TAS} RNA metabolic process, gene expression, mRNA splicing, via spliceosome, ncRNA metabolic process, spliceosomal complex assembly, spliceosomal snRNP assembly Cajal body, cytoplasm, cytosol, nuclear body, nucleoplasm, nucleus, spliceosomal complex protein binding Human UniProtKB:P12520 GEMIN7 Reactome UniProtKB {GO:0005515=PMID:12065586, GO:0010467=Reactome:REACT_71, GO:0015030=GO_REF:0000039, GO:0016070=Reactome:REACT_21257, GO:0034660=Reactome:REACT_11052, GO:0000387=Reactome:REACT_11066, GO:0005829=Reactome:REACT_10041, GO:0016604=PMID:12065586, GO:0005737=PMID:12065586, GO:0032797=GO_REF:0000002, GO:0000398=PMID:12065586, GO:0005681=GO_REF:0000037, GO:0005654=Reactome:REACT_10010} Q9H840 Gem-associated protein 7 protein 20130213 {GO:0005515=IPI, GO:0010467=TAS, GO:0015030=IEA, GO:0016070=TAS, GO:0034660=TAS, GO:0000387=TAS, GO:0005829=TAS, GO:0016604=IDA, GO:0005737=IDA, GO:0032797=IEA, GO:0000398=TAS, GO:0005681=IEA, GO:0005654=TAS} RNA metabolic process, gene expression, mRNA splicing, via spliceosome, ncRNA metabolic process, spliceosomal snRNP assembly Cajal body, SMN complex, cytoplasm, cytosol, nuclear body, nucleoplasm, spliceosomal complex protein binding Human GEMIN8 HPA UniProtKB {GO:0005515=PMID:17023415, GO:0005737=GO_REF:0000052, GO:0015030=GO_REF:0000039, GO:0032797=PMID:16434402, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005681=GO_REF:0000037, GO:0000387=PMID:16434402} Q9NWZ8 Gem-associated protein 8 protein 20111111 {GO:0005515=IPI, GO:0005737=IDA, GO:0015030=IEA, GO:0032797=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0005681=IEA, GO:0000387=IDA} spliceosomal snRNP assembly Cajal body, SMN complex, cytoplasm, nucleolus, nucleus, spliceosomal complex protein binding Human GET4 UniProtKB UniProtKB {GO:0006810=GO_REF:0000037, GO:0071816=PMID:20676083, GO:0071818=PMID:20676083, GO:0005829=PMID:20676083} Q7L5D6 Golgi to ER traffic protein 4 homolog protein 20101105 {GO:0006810=IEA, GO:0071816=IMP, GO:0071818=IDA, GO:0005829=IDA} tail-anchored membrane protein insertion into ER membrane, transport BAT3 complex, cytosol Human GFAP Reactome UniProtKB {GO:0005882=GO_REF:0000019, GO:0045109=GO_REF:0000019, GO:0031102=GO_REF:0000019, GO:0009611=GO_REF:0000019, GO:0060291=GO_REF:0000019, GO:0051580=GO_REF:0000019, GO:0042995=GO_REF:0000019, GO:0044297=GO_REF:0000019, GO:0005829=Reactome:REACT_115713, GO:0005737=PMID:12355421, GO:0005178=GO_REF:0000019, GO:0010625=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0014002=GO_REF:0000019, GO:0030198=GO_REF:0000019, GO:0005198=GO_REF:0000002, GO:0060020=GO_REF:0000019, GO:0005200=GO_REF:0000019, GO:0010977=GO_REF:0000019, GO:0019900=GO_REF:0000019} P14136 Glial fibrillary acidic protein protein 20110427 {GO:0005882=IEA, GO:0045109=IEA, GO:0031102=IEA, GO:0009611=IEA, GO:0060291=IEA, GO:0051580=IEA, GO:0042995=IEA, GO:0044297=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0005178=IEA, GO:0010625=IEA, GO:0016020=IEA, GO:0014002=IEA, GO:0030198=IEA, GO:0005198=IEA, GO:0060020=IEA, GO:0005200=IEA, GO:0010977=IEA, GO:0019900=IEA} Bergmann glial cell differentiation, astrocyte development, extracellular matrix organization, intermediate filament organization, long-term synaptic potentiation, negative regulation of neuron projection development, neuron projection regeneration, positive regulation of Schwann cell proliferation, regulation of neurotransmitter uptake, response to wounding cell body, cell projection, cytoplasm, cytosol, intermediate filament, membrane integrin binding, kinase binding, structural constituent of cytoskeleton, structural molecule activity Human GFER HPA UniProtKB {GO:0005515=PMID:12681488, GO:0008283=GO_REF:0000029, GO:0050660=PMID:22224850, GO:0006626=Reactome:REACT_118595, GO:0015035=PMID:22224850, GO:0005576=GO_REF:0000039, GO:0007283=GO_REF:0000029, GO:0005575=GO_REF:0000015, GO:0005739=GO_REF:0000052, GO:0005758=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0016972=GO_REF:0000003, GO:0008083=GO_REF:0000037, GO:0044267=Reactome:REACT_17015} P55789 FAD-linked sulfhydryl oxidase ALR protein 20111111 {GO:0005515=IPI, GO:0008283=NAS, GO:0050660=IDA, GO:0006626=TAS, GO:0015035=IDA, GO:0005576=IEA, GO:0007283=NAS, GO:0005575=ND, GO:0005739=IDA, GO:0005758=IEA, GO:0005737=IDA, GO:0016972=IEA, GO:0008083=IEA, GO:0044267=TAS} cell proliferation, cellular protein metabolic process, protein targeting to mitochondrion, spermatogenesis cellular_component, cytoplasm, extracellular region, mitochondrial intermembrane space, mitochondrion flavin adenine dinucleotide binding, growth factor activity, protein binding, protein disulfide oxidoreductase activity, thiol oxidase activity Human GFI1 BHF-UCL UniProtKB {GO:0005515=PMID:21570500, GO:0044212=PMID:15947108, GO:0009996=GO_REF:0000019, GO:0034121=PMID:20547752, GO:0005634=PMID:12874834, GO:0042660=GO_REF:0000019, GO:0016363=PMID:12874834, GO:0000083=PMID:8441411, GO:0017053=PMID:12874834, GO:0070105=PMID:11060035, GO:0016032=PMID:8441411, GO:0042472=GO_REF:0000019, GO:0042491=GO_REF:0000019, GO:0032088=GO_REF:0000024, GO:0000122=PMID:15947108, GO:0006351=GO_REF:0000037, GO:0016604=PMID:11060035, GO:0071222=PMID:20547752, GO:0045165=GO_REF:0000019, GO:0010977=PMID:19026687, GO:0008270=GO_REF:0000002, GO:0007638=GO_REF:0000019, GO:0045892=PMID:12874834, GO:0010956=PMID:15947108, GO:0010957=PMID:15947108} Q99684 Zinc finger protein Gfi-1 protein 20090407 {GO:0005515=IPI, GO:0044212=IDA, GO:0009996=IEA, GO:0034121=IDA, GO:0005634=IDA, GO:0042660=IEA, GO:0016363=IDA, GO:0000083=TAS, GO:0017053=IDA, GO:0070105=IDA, GO:0016032=TAS, GO:0042472=IEA, GO:0042491=IEA, GO:0032088=ISS, GO:0000122=IDA, GO:0006351=IEA, GO:0016604=IDA, GO:0071222=IEP, GO:0045165=IEA, GO:0010977=IDA, GO:0008270=IEA, GO:0007638=IEA, GO:0045892=IDA, GO:0010956=IDA, GO:0010957=IC} auditory receptor cell differentiation, cell fate commitment, cellular response to lipopolysaccharide, inner ear morphogenesis, mechanosensory behavior, negative regulation of NF-kappaB transcription factor activity, negative regulation of calcidiol 1-monooxygenase activity, negative regulation of cell fate specification, negative regulation of neuron projection development, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, negative regulation of vitamin D biosynthetic process, positive regulation of cell fate specification, positive regulation of interleukin-6-mediated signaling pathway, regulation of toll-like receptor signaling pathway, regulation of transcription involved in G1/S phase of mitotic cell cycle, transcription, DNA-dependent, viral reproduction nuclear body, nuclear matrix, nucleus, transcriptional repressor complex protein binding, transcription regulatory region DNA binding, zinc ion binding Human GFI1B BHF-UCL UniProtKB {GO:0005515=PMID:16713569, GO:0005667=PMID:15920471, GO:0006366=PMID:9566867, GO:0008283=PMID:9566867, GO:0007275=GO_REF:0000037, GO:0005634=PMID:12874834, GO:0000122=PMID:9566867, GO:0003677=GO_REF:0000037, GO:0016363=PMID:12874834, GO:0000114=PMID:9566867, GO:0001085=PMID:15920471, GO:0008270=GO_REF:0000002, GO:0016568=GO_REF:0000037} Q5VTD9 Zinc finger protein Gfi-1b protein 20110810 {GO:0005515=IPI, GO:0005667=IDA, GO:0006366=TAS, GO:0008283=TAS, GO:0007275=IEA, GO:0005634=IDA, GO:0000122=TAS, GO:0003677=IEA, GO:0016363=IDA, GO:0000114=TAS, GO:0001085=IPI, GO:0008270=IEA, GO:0016568=IEA} cell proliferation, chromatin modification, multicellular organismal development, negative regulation of transcription from RNA polymerase II promoter, regulation of transcription involved in G1 phase of mitotic cell cycle, transcription from RNA polymerase II promoter nuclear matrix, nucleus, transcription factor complex DNA binding, RNA polymerase II transcription factor binding, protein binding, zinc ion binding Human GFM1 UniProtKB UniProtKB {GO:0006184=PMID:19716793, GO:0005739=GO_REF:0000039, GO:0005622=GO_REF:0000002, GO:0070125=PMID:19716793, GO:0003924=PMID:19716793, GO:0005525=GO_REF:0000037, GO:0003746=GO_REF:0000038} Q9H9M0 Elongation factor G, mitochondrial protein 20130413 {GO:0006184=IDA, GO:0005739=IEA, GO:0005622=IEA, GO:0070125=IDA, GO:0003924=IDA, GO:0005525=IEA, GO:0003746=IEA} GTP catabolic process, mitochondrial translational elongation intracellular, mitochondrion GTP binding, GTPase activity, translation elongation factor activity Human UniProtKB-KW:KW-0251 GFM2 GOC UniProtKB {GO:0006184=PMID:19716793, GO:0005739=GO_REF:0000039, GO:0070125=PMID:19716793, GO:0032543=PMID:19716793, GO:0003924=PMID:19716793, GO:0032790=PMID:19716793, GO:0003746=PMID:19716793, GO:0005525=GO_REF:0000037} Q969S9 Ribosome-releasing factor 2, mitochondrial protein 20130413 {GO:0006184=IDA, GO:0005739=IEA, GO:0070125=IDA, GO:0032543=IDA, GO:0003924=IDA, GO:0032790=IDA, GO:0003746=IDA, GO:0005525=IEA} GTP catabolic process, mitochondrial translation, mitochondrial translational elongation, ribosome disassembly mitochondrion GTP binding, GTPase activity, translation elongation factor activity Human GFOD1 UniProtKB UniProtKB {GO:0016491=GO_REF:0000037, GO:0005576=GO_REF:0000039} Q9NXC2 Glucose-fructose oxidoreductase domain-containing protein 1 protein 20130413 {GO:0016491=IEA, GO:0005576=IEA} extracellular region oxidoreductase activity Human UniProtKB-SubCell:SL-0243 GFOD2 UniProtKB UniProtKB {GO:0030198=GO_REF:0000019, GO:0005578=GO_REF:0000039, GO:0016491=GO_REF:0000037} Q3B7J2 Glucose-fructose oxidoreductase domain-containing protein 2 protein 20130413 {GO:0030198=IEA, GO:0005578=IEA, GO:0016491=IEA} extracellular matrix organization proteinaceous extracellular matrix oxidoreductase activity Human UniProtKB-SubCell:SL-0111 GFPT1 Reactome UniProtKB {GO:0004360=GO_REF:0000003, GO:0032869=GO_REF:0000019, GO:0006042=GO_REF:0000019, GO:0006048=Reactome:REACT_22394, GO:0045719=GO_REF:0000019, GO:0030968=Reactome:REACT_18356, GO:0005829=Reactome:REACT_115595, GO:0016051=GO_REF:0000002, GO:0006112=PMID:1460020, GO:0009744=GO_REF:0000019, GO:0051289=GO_REF:0000019, GO:0030246=GO_REF:0000002, GO:0006987=Reactome:REACT_18368, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0006002=GO_REF:0000019, GO:0016597=GO_REF:0000019, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426, GO:0006541=GO_REF:0000037} Q06210 "Glutamine--fructose-6-phosphate aminotransferase ""isomerizing"" 1" protein 20130301 {GO:0004360=IEA, GO:0032869=IEA, GO:0006042=IEA, GO:0006048=TAS, GO:0045719=IEA, GO:0030968=TAS, GO:0005829=TAS, GO:0016051=IEA, GO:0006112=TAS, GO:0009744=IEA, GO:0051289=IEA, GO:0030246=IEA, GO:0006987=TAS, GO:0006488=TAS, GO:0044267=TAS, GO:0006002=IEA, GO:0016597=IEA, GO:0043687=TAS, GO:0018279=TAS, GO:0006541=IEA} UDP-N-acetylglucosamine biosynthetic process, activation of signaling protein activity involved in unfolded protein response, carbohydrate biosynthetic process, cellular protein metabolic process, cellular response to insulin stimulus, dolichol-linked oligosaccharide biosynthetic process, endoplasmic reticulum unfolded protein response, energy reserve metabolic process, fructose 6-phosphate metabolic process, glucosamine biosynthetic process, glutamine metabolic process, negative regulation of glycogen biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine, protein homotetramerization, response to sucrose stimulus cytosol amino acid binding, carbohydrate binding, glutamine-fructose-6-phosphate transaminase (isomerizing) activity Human GFPT2 Reactome UniProtKB {GO:0004360=GO_REF:0000003, GO:0006048=Reactome:REACT_22394, GO:0005829=Reactome:REACT_22115, GO:0016051=GO_REF:0000002, GO:0006112=PMID:10198162, GO:0008152=GO_REF:0000002, GO:0030246=GO_REF:0000002, GO:0006488=Reactome:REACT_22433, GO:0006002=PMID:10198162, GO:0044267=Reactome:REACT_17015, GO:0006541=GO_REF:0000037, GO:0018279=Reactome:REACT_22426, GO:0043687=Reactome:REACT_22161} O94808 "Glutamine--fructose-6-phosphate aminotransferase ""isomerizing"" 2" protein 20130301 {GO:0004360=IEA, GO:0006048=TAS, GO:0005829=TAS, GO:0016051=IEA, GO:0006112=TAS, GO:0008152=IEA, GO:0030246=IEA, GO:0006488=TAS, GO:0006002=TAS, GO:0044267=TAS, GO:0006541=IEA, GO:0018279=TAS, GO:0043687=TAS} UDP-N-acetylglucosamine biosynthetic process, carbohydrate biosynthetic process, cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, energy reserve metabolic process, fructose 6-phosphate metabolic process, glutamine metabolic process, metabolic process, post-translational protein modification, protein N-linked glycosylation via asparagine cytosol carbohydrate binding, glutamine-fructose-6-phosphate transaminase (isomerizing) activity Human GFRA1 GOC UniProtKB {GO:0030424=GO_REF:0000019, GO:0001822=GO_REF:0000019, GO:0005102=PMID:9545641, GO:0035860=PMID:10829012, GO:0031225=GO_REF:0000037, GO:0005615=GO_REF:0000019, GO:0043235=GO_REF:0000019, GO:0005178=GO_REF:0000019, GO:0016167=PMID:10829012, GO:0016477=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0043025=GO_REF:0000019, GO:0004872=GO_REF:0000029, GO:0009897=GO_REF:0000019, GO:0007166=PMID:8674117, GO:0008584=GO_REF:0000019, GO:0019898=GO_REF:0000029} P56159 GDNF family receptor alpha-1 protein 20130413 {GO:0030424=IEA, GO:0001822=IEA, GO:0005102=TAS, GO:0035860=TAS, GO:0031225=IEA, GO:0005615=IEA, GO:0043235=IEA, GO:0005178=IEA, GO:0016167=TAS, GO:0016477=IEA, GO:0007411=TAS, GO:0043025=IEA, GO:0004872=NAS, GO:0009897=IEA, GO:0007166=NAS, GO:0008584=IEA, GO:0019898=NAS} axon guidance, cell migration, cell surface receptor signaling pathway, glial cell-derived neurotrophic factor receptor signaling pathway, kidney development, male gonad development anchored to membrane, axon, external side of plasma membrane, extracellular space, extrinsic to membrane, neuronal cell body, receptor complex glial cell-derived neurotrophic factor receptor activity, integrin binding, receptor activity, receptor binding Human GFRA2 GOC UniProtKB {GO:0016167=PMID:10829012, GO:0005886=GO_REF:0000039, GO:0035860=PMID:10829012, GO:0004872=GO_REF:0000002, GO:0031225=GO_REF:0000037, GO:0007169=PMID:9192898, GO:0019898=PMID:10829012, GO:0007399=GO_REF:0000019} O00451 GDNF family receptor alpha-2 protein 20130413 {GO:0016167=TAS, GO:0005886=IEA, GO:0035860=TAS, GO:0004872=IEA, GO:0031225=IEA, GO:0007169=TAS, GO:0019898=TAS, GO:0007399=IEA} glial cell-derived neurotrophic factor receptor signaling pathway, nervous system development, transmembrane receptor protein tyrosine kinase signaling pathway anchored to membrane, extrinsic to membrane, plasma membrane glial cell-derived neurotrophic factor receptor activity, receptor activity Human GFRA3 HPA UniProtKB {GO:0005886=GO_REF:0000052, GO:0005102=PMID:9407096, GO:0031225=GO_REF:0000037, GO:0048485=GO_REF:0000019, GO:0007399=PMID:9490034, GO:0043231=GO_REF:0000052, GO:0007165=PMID:9576965, GO:0005737=GO_REF:0000052, GO:0007422=PMID:9576965, GO:0001764=GO_REF:0000019, GO:0008046=GO_REF:0000019, GO:0009897=GO_REF:0000019, GO:0019898=PMID:9490034} O60609 GDNF family receptor alpha-3 protein 20101115 {GO:0005886=IDA, GO:0005102=TAS, GO:0031225=IEA, GO:0048485=IEA, GO:0007399=TAS, GO:0043231=IDA, GO:0007165=TAS, GO:0005737=IDA, GO:0007422=TAS, GO:0001764=IEA, GO:0008046=IEA, GO:0009897=IEA, GO:0019898=TAS} nervous system development, neuron migration, peripheral nervous system development, signal transduction, sympathetic nervous system development anchored to membrane, cytoplasm, external side of plasma membrane, extrinsic to membrane, intracellular membrane-bounded organelle, plasma membrane axon guidance receptor activity, receptor binding Human GFRA4 UniProtKB UniProtKB {GO:0030279=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0016167=GO_REF:0000019, GO:0031225=GO_REF:0000037, GO:0005615=GO_REF:0000019} Q9GZZ7 GDNF family receptor alpha-4 protein 20130413 {GO:0030279=IEA, GO:0005886=IEA, GO:0016167=IEA, GO:0031225=IEA, GO:0005615=IEA} negative regulation of ossification anchored to membrane, extracellular space, plasma membrane glial cell-derived neurotrophic factor receptor activity Human UniProtKB-SubCell:SL-0039 GFRAL ENSEMBL UniProtKB {GO:0043066=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0031098=GO_REF:0000019} Q6UXV0 GDNF family receptor alpha-like protein 20130413 {GO:0043066=IEA, GO:0005886=IEA, GO:0016021=IEA, GO:0031098=IEA} negative regulation of apoptotic process, stress-activated protein kinase signaling cascade integral to membrane, plasma membrane Human Ensembl:ENSMUSP00000074421 GGA1 IntAct UniProtKB {GO:0005515=PMID:20676133, GO:0005622=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0030131=GO_REF:0000002, GO:0005794=PMID:20214818, GO:0016192=GO_REF:0000002, GO:0006886=PMID:20211637, GO:0010008=GO_REF:0000039} Q9UJY5 ADP-ribosylation factor-binding protein GGA1 protein 20130415 {GO:0005515=IPI, GO:0005622=IEA, GO:0003674=ND, GO:0030131=IEA, GO:0005794=TAS, GO:0016192=IEA, GO:0006886=TAS, GO:0010008=IEA} intracellular protein transport, vesicle-mediated transport Golgi apparatus, clathrin adaptor complex, endosome membrane, intracellular molecular_function, protein binding Human UniProtKB:Q9Y3C5 GGA2 BHF-UCL UniProtKB {GO:0005515=PMID:12429846, GO:0005802=PMID:10749927, GO:0005622=GO_REF:0000002, GO:0030131=GO_REF:0000002, GO:0005794=GO_REF:0000039, GO:0030306=PMID:10749927, GO:0030136=PMID:19478182, GO:0016192=GO_REF:0000002, GO:0006886=PMID:10749927, GO:0010008=GO_REF:0000039} Q9UJY4 ADP-ribosylation factor-binding protein GGA2 protein 20110126 {GO:0005515=IPI, GO:0005802=IDA, GO:0005622=IEA, GO:0030131=IEA, GO:0005794=IEA, GO:0030306=IDA, GO:0030136=IDA, GO:0016192=IEA, GO:0006886=NAS, GO:0010008=IEA} intracellular protein transport, vesicle-mediated transport Golgi apparatus, clathrin adaptor complex, clathrin-coated vesicle, endosome membrane, intracellular, trans-Golgi network ADP-ribosylation factor binding, protein binding Human UniProtKB:Q14677 GGA3 IntAct UniProtKB {GO:0005515=PMID:15039775, GO:0005802=PMID:10749927, GO:0030131=GO_REF:0000002, GO:0005794=GO_REF:0000039, GO:0030306=PMID:10749927, GO:0016192=GO_REF:0000002, GO:0006886=PMID:10749927, GO:0010008=GO_REF:0000039} Q9NZ52 ADP-ribosylation factor-binding protein GGA3 protein 20130415 {GO:0005515=IPI, GO:0005802=IDA, GO:0030131=IEA, GO:0005794=IEA, GO:0030306=IDA, GO:0016192=IEA, GO:0006886=NAS, GO:0010008=IEA} intracellular protein transport, vesicle-mediated transport Golgi apparatus, clathrin adaptor complex, endosome membrane, trans-Golgi network ADP-ribosylation factor binding, protein binding Human UniProtKB:P0CG47 GGCT Reactome UniProtKB {GO:0003839=Reactome:REACT_75929, GO:0006805=Reactome:REACT_13433, GO:0006750=Reactome:REACT_6960, GO:0001836=PMID:16765912, GO:0044281=Reactome:REACT_111217, GO:0042803=PMID:17932939, GO:0005829=Reactome:REACT_75929} O75223 Gamma-glutamylcyclotransferase protein 20110408 {GO:0003839=TAS, GO:0006805=TAS, GO:0006750=TAS, GO:0001836=IMP, GO:0044281=TAS, GO:0042803=IDA, GO:0005829=TAS} glutathione biosynthetic process, release of cytochrome c from mitochondria, small molecule metabolic process, xenobiotic metabolic process cytosol gamma-glutamylcyclotransferase activity, protein homodimerization activity Human GGCX Reactome UniProtKB {GO:0017187=Reactome:REACT_1132, GO:0016020=PMID:1749935, GO:0007596=PMID:9845520, GO:0008488=GO_REF:0000002, GO:0005789=Reactome:REACT_2045, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006464=PMID:1749935, GO:0043687=Reactome:REACT_22161} P38435 Vitamin K-dependent gamma-carboxylase protein 20130301 {GO:0017187=TAS, GO:0016020=TAS, GO:0007596=TAS, GO:0008488=IEA, GO:0005789=TAS, GO:0016021=IEA, GO:0044267=TAS, GO:0006464=TAS, GO:0043687=TAS} blood coagulation, cellular protein metabolic process, cellular protein modification process, peptidyl-glutamic acid carboxylation, post-translational protein modification endoplasmic reticulum membrane, integral to membrane, membrane gamma-glutamyl carboxylase activity Human GGH PINC UniProtKB {GO:0042470=GO_REF:0000039, GO:0032868=GO_REF:0000019, GO:0034722=PMID:11005824, GO:0045471=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0008242=PMID:8816764, GO:0005764=GO_REF:0000039, GO:0010043=GO_REF:0000019, GO:0005615=GO_REF:0000039, GO:0008238=PMID:8816764, GO:0005829=GO_REF:0000019, GO:0006541=GO_REF:0000002} Q92820 Gamma-glutamyl hydrolase protein 20030904 {GO:0042470=IEA, GO:0032868=IEA, GO:0034722=IDA, GO:0045471=IEA, GO:0042493=IEA, GO:0008242=TAS, GO:0005764=IEA, GO:0010043=IEA, GO:0005615=IEA, GO:0008238=TAS, GO:0005829=IEA, GO:0006541=IEA} glutamine metabolic process, response to drug, response to ethanol, response to insulin stimulus, response to zinc ion cytosol, extracellular space, lysosome, melanosome exopeptidase activity, gamma-glutamyl-peptidase activity, omega peptidase activity Human GGN UniProtKB UniProtKB {GO:0048471=GO_REF:0000019, GO:0008104=GO_REF:0000019, GO:0007276=GO_REF:0000024, GO:0046983=GO_REF:0000019, GO:0005730=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q86UU5 Gametogenetin protein 20061106 {GO:0048471=IEA, GO:0008104=IEA, GO:0007276=ISS, GO:0046983=IEA, GO:0005730=IEA, GO:0007275=IEA, GO:0007283=IEA, GO:0030154=IEA} cell differentiation, gamete generation, multicellular organismal development, protein localization, spermatogenesis nucleolus, perinuclear region of cytoplasm protein dimerization activity Human UniProtKB:Q80WJ1 GGNBP2 UniProtKB UniProtKB {GO:0016023=GO_REF:0000039, GO:0005634=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q9H3C7 Gametogenetin-binding protein 2 protein 20130413 {GO:0016023=IEA, GO:0005634=IEA, GO:0007275=IEA, GO:0007283=IEA, GO:0030154=IEA} cell differentiation, multicellular organismal development, spermatogenesis cytoplasmic membrane-bounded vesicle, nucleus Human UniProtKB-SubCell:SL-0088 GGPS1 Reactome UniProtKB {GO:0006695=Reactome:REACT_9405, GO:0045337=GO_REF:0000041, GO:0033386=GO_REF:0000041, GO:0004337=GO_REF:0000003, GO:0004161=GO_REF:0000003, GO:0033384=GO_REF:0000041, GO:0044281=Reactome:REACT_111217, GO:0008299=GO_REF:0000038, GO:0004311=PMID:10026212, GO:0006720=PMID:10026212, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_147826} O95749 Geranylgeranyl pyrophosphate synthase protein 20130213 {GO:0006695=TAS, GO:0045337=IEA, GO:0033386=IEA, GO:0004337=IEA, GO:0004161=IEA, GO:0033384=IEA, GO:0044281=TAS, GO:0008299=IEA, GO:0004311=IDA, GO:0006720=IDA, GO:0046872=IEA, GO:0005829=TAS} cholesterol biosynthetic process, farnesyl diphosphate biosynthetic process, geranyl diphosphate biosynthetic process, geranylgeranyl diphosphate biosynthetic process, isoprenoid biosynthetic process, isoprenoid metabolic process, small molecule metabolic process cytosol dimethylallyltranstransferase activity, farnesyltranstransferase activity, geranyltranstransferase activity, metal ion binding Human GGT1 Reactome UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0005515=PMID:15528406, GO:0006520=PMID:2904146, GO:0019370=PMID:14754911, GO:0019344=GO_REF:0000024, GO:0006805=Reactome:REACT_13433, GO:0005886=Reactome:REACT_75920, GO:0050727=GO_REF:0000024, GO:0006749=PMID:18357469, GO:0002682=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0007283=GO_REF:0000024, GO:0006691=Reactome:REACT_150420, GO:0031362=PMID:18357469, GO:0016787=GO_REF:0000037, GO:0016020=GO_REF:0000029, GO:0003840=PMID:18357469, GO:0006750=Reactome:REACT_6960, GO:0016021=GO_REF:0000037} P19440 Gamma-glutamyltranspeptidase 1 protein 20120224 {GO:0019369=TAS, GO:0005515=IPI, GO:0006520=TAS, GO:0019370=IMP, GO:0019344=ISS, GO:0006805=TAS, GO:0005886=TAS, GO:0050727=ISS, GO:0006749=TAS, GO:0002682=ISS, GO:0044281=TAS, GO:0007283=ISS, GO:0006691=TAS, GO:0031362=TAS, GO:0016787=IEA, GO:0016020=NAS, GO:0003840=TAS, GO:0006750=TAS, GO:0016021=IEA} arachidonic acid metabolic process, cellular amino acid metabolic process, cysteine biosynthetic process, glutathione biosynthetic process, glutathione metabolic process, leukotriene biosynthetic process, leukotriene metabolic process, regulation of immune system process, regulation of inflammatory response, small molecule metabolic process, spermatogenesis, xenobiotic metabolic process anchored to external side of plasma membrane, integral to membrane, membrane, plasma membrane gamma-glutamyltransferase activity, hydrolase activity, protein binding Human GGT7 UniProtKB UniProtKB {GO:0019370=GO_REF:0000024, GO:0016787=GO_REF:0000037, GO:0003840=PMID:18357469, GO:0006750=GO_REF:0000037, GO:0006749=PMID:18357469, GO:0016021=GO_REF:0000037, GO:0031362=PMID:18357469} Q9UJ14 Gamma-glutamyltransferase 7 protein 20110915 {GO:0019370=ISS, GO:0016787=IEA, GO:0003840=TAS, GO:0006750=IEA, GO:0006749=TAS, GO:0016021=IEA, GO:0031362=TAS} glutathione biosynthetic process, glutathione metabolic process, leukotriene biosynthetic process anchored to external side of plasma membrane, integral to membrane gamma-glutamyltransferase activity, hydrolase activity Human GGTLC1 UniProtKB UniProtKB {GO:0019370=GO_REF:0000024, GO:0003840=PMID:18357469, GO:0006749=PMID:18357469, GO:0031362=PMID:18357469} Q9BX51 Gamma-glutamyltransferase light chain 1 protein 20110915 {GO:0019370=ISS, GO:0003840=TAS, GO:0006749=TAS, GO:0031362=TAS} glutathione metabolic process, leukotriene biosynthetic process anchored to external side of plasma membrane gamma-glutamyltransferase activity Human GH1 BHF-UCL UniProtKB {GO:0005515=PMID:9353194, GO:0010535=PMID:12552091, GO:0005148=PMID:7984244, GO:0042517=PMID:12552091, GO:0005131=PMID:1549776, GO:0050731=PMID:7782332, GO:0042523=PMID:8923468, GO:0014068=PMID:7782332, GO:0060396=PMID:8063815, GO:0005576=Reactome:REACT_116060, GO:0060397=Reactome:REACT_111133, GO:0070977=PMID:20110402, GO:0005615=PMID:11549663, GO:0007259=PMID:8063815, GO:0046872=GO_REF:0000037, GO:0046427=PMID:8923468, GO:0005179=GO_REF:0000037, GO:0015758=PMID:9144201, GO:0043568=PMID:7565946, GO:0043406=PMID:8063815, GO:0040018=PMID:8496314, GO:0032355=PMID:12552091, GO:0008083=PMID:9360546, GO:0002092=PMID:9360546} P01241 Somatotropin protein 20081205 {GO:0005515=IPI, GO:0010535=IDA, GO:0005148=IPI, GO:0042517=IDA, GO:0005131=IPI, GO:0050731=IDA, GO:0042523=IDA, GO:0014068=IDA, GO:0060396=IDA, GO:0005576=TAS, GO:0060397=TAS, GO:0070977=IDA, GO:0005615=IDA, GO:0007259=IDA, GO:0046872=IEA, GO:0046427=IDA, GO:0005179=IEA, GO:0015758=IDA, GO:0043568=IDA, GO:0043406=TAS, GO:0040018=IMP, GO:0032355=IDA, GO:0008083=IPI, GO:0002092=IDA} JAK-STAT cascade, JAK-STAT cascade involved in growth hormone signaling pathway, bone maturation, glucose transport, growth hormone receptor signaling pathway, positive regulation of JAK-STAT cascade, positive regulation of MAP kinase activity, positive regulation of activation of JAK2 kinase activity, positive regulation of insulin-like growth factor receptor signaling pathway, positive regulation of multicellular organism growth, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of receptor internalization, positive regulation of tyrosine phosphorylation of Stat3 protein, positive regulation of tyrosine phosphorylation of Stat5 protein, response to estradiol stimulus extracellular region, extracellular space growth factor activity, growth hormone receptor binding, hormone activity, metal ion binding, prolactin receptor binding, protein binding Human UniProtKB:P10912 GH2 Reactome UniProtKB {GO:0005179=GO_REF:0000037, GO:0005576=Reactome:REACT_116060, GO:0060397=Reactome:REACT_111133} P01242 Growth hormone variant protein 20130301 {GO:0005179=IEA, GO:0005576=TAS, GO:0060397=TAS} JAK-STAT cascade involved in growth hormone signaling pathway extracellular region hormone activity Human GHITM IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005743=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0016021=GO_REF:0000029} Q9H3K2 Growth hormone-inducible transmembrane protein protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0003674=ND, GO:0005743=IEA, GO:0006915=IEA, GO:0016021=NAS} apoptotic process, biological_process integral to membrane, mitochondrial inner membrane molecular_function, protein binding Human UniProtKB:Q6PDS3 GHR BHF-UCL UniProtKB {GO:0005515=PMID:10502458, GO:0006549=GO_REF:0000024, GO:0019530=GO_REF:0000024, GO:0045597=GO_REF:0000019, GO:0050731=GO_REF:0000024, GO:0005615=PMID:2825030, GO:0042803=PMID:8137822, GO:0043025=GO_REF:0000019, GO:0004903=GO_REF:0000019, GO:0042169=GO_REF:0000019, GO:0070064=PMID:2825030, GO:0032869=GO_REF:0000019, GO:0019901=GO_REF:0000024, GO:0009986=PMID:8137822, GO:0019903=GO_REF:0000019, GO:1901215=GO_REF:0000019, GO:0043278=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0046449=GO_REF:0000024, GO:0006897=GO_REF:0000037, GO:0043235=PMID:8137822, GO:0006600=GO_REF:0000024, GO:0005887=PMID:8137822, GO:0019898=GO_REF:0000019, GO:0042977=GO_REF:0000024, GO:0005886=Reactome:REACT_111235, GO:0000255=GO_REF:0000024, GO:0042523=PMID:2825030, GO:0060396=PMID:7565946, GO:0005634=GO_REF:0000019, GO:0060397=Reactome:REACT_111133, GO:0032094=GO_REF:0000019, GO:0032870=PMID:7565946, GO:0005739=GO_REF:0000019, GO:0000187=GO_REF:0000024, GO:0006101=GO_REF:0000024, GO:0006105=GO_REF:0000024, GO:0060351=GO_REF:0000019, GO:0040014=GO_REF:0000024, GO:0006103=GO_REF:0000024, GO:0006631=GO_REF:0000024, GO:0044236=PMID:8137822, GO:0070195=PMID:8137822, GO:0006573=GO_REF:0000024, GO:0040018=PMID:2813379, GO:0070555=GO_REF:0000019, GO:0042517=PMID:2825030, GO:0006107=GO_REF:0000024, GO:0005576=Reactome:REACT_111114, GO:0007259=GO_REF:0000024, GO:0009755=GO_REF:0000019, GO:0048009=PMID:7565946, GO:0016021=PMID:1549776, GO:0017046=PMID:2825030} P10912 Growth hormone receptor protein 20081207 {GO:0005515=IPI, GO:0006549=ISS, GO:0019530=ISS, GO:0045597=IEA, GO:0050731=ISS, GO:0005615=IMP, GO:0042803=IDA, GO:0043025=IEA, GO:0004903=IEA, GO:0042169=IEA, GO:0070064=ISS, GO:0032869=IEA, GO:0019901=ISS, GO:0009986=IDA, GO:0019903=IEA, GO:1901215=IEA, GO:0043278=IEA, GO:0051384=IEA, GO:0046449=ISS, GO:0006897=IEA, GO:0043235=IDA, GO:0006600=ISS, GO:0005887=IDA, GO:0019898=IEA, GO:0042977=ISS, GO:0005886=TAS, GO:0000255=ISS, GO:0042523=ISS, GO:0060396=IMP, GO:0005634=IEA, GO:0060397=TAS, GO:0032094=IEA, GO:0032870=IMP, GO:0005739=IEA, GO:0000187=ISS, GO:0006101=ISS, GO:0006105=ISS, GO:0060351=IEA, GO:0040014=ISS, GO:0006103=ISS, GO:0006631=ISS, GO:0044236=IMP, GO:0070195=IDA, GO:0006573=ISS, GO:0040018=IMP, GO:0070555=IEA, GO:0042517=ISS, GO:0006107=ISS, GO:0005576=TAS, GO:0007259=ISS, GO:0009755=IEA, GO:0048009=IMP, GO:0016021=IDA, GO:0017046=IPI} 2-oxoglutarate metabolic process, JAK-STAT cascade, JAK-STAT cascade involved in growth hormone signaling pathway, activation of JAK2 kinase activity, activation of MAPK activity, allantoin metabolic process, cartilage development involved in endochondral bone morphogenesis, cellular response to hormone stimulus, cellular response to insulin stimulus, citrate metabolic process, creatine metabolic process, creatinine metabolic process, endocytosis, fatty acid metabolic process, growth hormone receptor signaling pathway, hormone-mediated signaling pathway, insulin-like growth factor receptor signaling pathway, isoleucine metabolic process, multicellular organismal metabolic process, negative regulation of neuron death, oxaloacetate metabolic process, positive regulation of cell differentiation, positive regulation of multicellular organism growth, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of tyrosine phosphorylation of Stat3 protein, positive regulation of tyrosine phosphorylation of Stat5 protein, regulation of multicellular organism growth, response to food, response to glucocorticoid stimulus, response to interleukin-1, response to morphine, succinate metabolic process, taurine metabolic process, valine metabolic process cell surface, extracellular region, extracellular space, extrinsic to membrane, growth hormone receptor complex, integral to membrane, integral to plasma membrane, mitochondrion, neuronal cell body, nucleus, plasma membrane, receptor complex SH2 domain binding, growth hormone receptor activity, peptide hormone binding, proline-rich region binding, protein binding, protein homodimerization activity, protein kinase binding, protein phosphatase binding Human UniProtKB:P16882 GHRH BHF-UCL UniProtKB {GO:0021984=GO_REF:0000024, GO:0060124=PMID:11773624, GO:0008284=PMID:12867592, GO:0046005=PMID:15538933, GO:0030819=PMID:7680413, GO:0007267=PMID:6192430, GO:0005576=PMID:11773624, GO:0005615=GO_REF:0000024, GO:0032094=GO_REF:0000024, GO:0031770=PMID:7680413, GO:0043568=PMID:11773624, GO:0016608=PMID:18329818, GO:0043195=GO_REF:0000024, GO:0019933=PMID:7680413, GO:0030252=PMID:2857452, GO:0007189=PMID:1333056, GO:0040018=PMID:8421089} P01286 Somatoliberin protein 20081129 {GO:0021984=ISS, GO:0060124=NAS, GO:0008284=IDA, GO:0046005=IMP, GO:0030819=IDA, GO:0007267=TAS, GO:0005576=NAS, GO:0005615=ISS, GO:0032094=ISS, GO:0031770=IPI, GO:0043568=NAS, GO:0016608=IDA, GO:0043195=ISS, GO:0019933=IDA, GO:0030252=IDA, GO:0007189=IC, GO:0040018=IMP} adenohypophysis development, adenylate cyclase-activating G-protein coupled receptor signaling pathway, cAMP-mediated signaling, cell-cell signaling, growth hormone secretion, positive regulation of cAMP biosynthetic process, positive regulation of cell proliferation, positive regulation of circadian sleep/wake cycle, REM sleep, positive regulation of growth hormone secretion, positive regulation of insulin-like growth factor receptor signaling pathway, positive regulation of multicellular organism growth, response to food extracellular region, extracellular space, terminal bouton growth hormone-releasing hormone activity, growth hormone-releasing hormone receptor binding Human GHRHR UniProtKB UniProtKB {GO:0005515=PMID:7680413, GO:0060124=PMID:11773624, GO:0008284=PMID:12867592, GO:0043627=PMID:9482665, GO:0005886=GO_REF:0000040, GO:0030819=PMID:7680413, GO:0005637=PMID:10461027, GO:0033143=GO_REF:0000019, GO:0016520=PMID:10962031, GO:0008340=GO_REF:0000019, GO:0016363=PMID:10461027, GO:0005640=PMID:10461027, GO:0048609=PMID:15944917, GO:0030104=GO_REF:0000019, GO:0007190=GO_REF:0000019, GO:0005737=PMID:10461027, GO:0019838=PMID:7680413, GO:0030252=GO_REF:0000019, GO:0048469=GO_REF:0000019, GO:0040018=PMID:8528260, GO:0030141=PMID:10461027, GO:0032868=PMID:17356054, GO:0051246=GO_REF:0000019, GO:0032869=GO_REF:0000019, GO:0009986=PMID:1333056, GO:0004930=PMID:1333056, GO:0060133=GO_REF:0000019, GO:0051384=PMID:9482665, GO:0008150=GO_REF:0000015, GO:0007186=GO_REF:0000029, GO:0007595=GO_REF:0000019, GO:0043568=PMID:11773624, GO:0019933=PMID:7680413, GO:0042445=GO_REF:0000019, GO:0007189=PMID:1333056, GO:0016021=PMID:10962031, GO:0017046=PMID:7680413} Q9HB45 Growth hormone-releasing hormone receptor protein 20021106 {GO:0005515=IPI, GO:0060124=NAS, GO:0008284=IDA, GO:0043627=IDA, GO:0005886=IEA, GO:0030819=IDA, GO:0005637=IDA, GO:0033143=IEA, GO:0016520=NAS, GO:0008340=IEA, GO:0016363=IDA, GO:0005640=IDA, GO:0048609=NAS, GO:0030104=IEA, GO:0007190=IEA, GO:0005737=IDA, GO:0019838=IPI, GO:0030252=IEA, GO:0048469=IEA, GO:0040018=IMP, GO:0030141=IDA, GO:0032868=IMP, GO:0051246=IEA, GO:0032869=IEA, GO:0009986=IDA, GO:0004930=IC, GO:0060133=IEA, GO:0051384=IDA, GO:0008150=ND, GO:0007186=NAS, GO:0007595=IEA, GO:0043568=NAS, GO:0019933=IMP, GO:0042445=IEA, GO:0007189=IDA, GO:0016021=NAS, GO:0017046=IPI} G-protein coupled receptor signaling pathway, activation of adenylate cyclase activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, biological_process, cAMP-mediated signaling, cell maturation, cellular response to insulin stimulus, determination of adult lifespan, growth hormone secretion, hormone metabolic process, lactation, multicellular organismal reproductive process, positive regulation of cAMP biosynthetic process, positive regulation of cell proliferation, positive regulation of growth hormone secretion, positive regulation of insulin-like growth factor receptor signaling pathway, positive regulation of multicellular organism growth, regulation of intracellular steroid hormone receptor signaling pathway, regulation of protein metabolic process, response to estrogen stimulus, response to glucocorticoid stimulus, response to insulin stimulus, somatotropin secreting cell development, water homeostasis cell surface, cytoplasm, integral to membrane, nuclear inner membrane, nuclear matrix, nuclear outer membrane, plasma membrane, secretory granule G-protein coupled receptor activity, growth factor binding, growth hormone-releasing hormone receptor activity, peptide hormone binding, protein binding Human GHRL GOC UniProtKB {GO:0008343=GO_REF:0000024, GO:0060124=PMID:18329818, GO:0030424=PMID:17113048, GO:0043627=PMID:15292338, GO:0051216=PMID:15576457, GO:0061098=PMID:15350694, GO:0032691=PMID:15232612, GO:0032100=GO_REF:0000024, GO:0060399=PMID:12566947, GO:0045409=PMID:15232612, GO:0007204=GO_REF:0000024, GO:0001696=GO_REF:0000019, GO:0005615=PMID:15039149, GO:0000187=PMID:15350694, GO:0046697=PMID:17494105, GO:0005737=GO_REF:0000019, GO:0030296=PMID:15350694, GO:0040013=GO_REF:0000019, GO:0042127=PMID:16394173, GO:0006006=PMID:17392603, GO:0051461=PMID:12566947, GO:0030252=PMID:16511605, GO:0032024=GO_REF:0000024, GO:0031768=PMID:16511605, GO:0009725=PMID:15232612, GO:0040018=PMID:16511605, GO:0046676=GO_REF:0000019, GO:0046010=PMID:18329818, GO:0051464=PMID:18329818, GO:0043400=PMID:17201814, GO:0051965=PMID:16491079, GO:0043066=PMID:15158140, GO:0001664=PMID:10604470, GO:0042536=PMID:15232612, GO:0060079=GO_REF:0000019, GO:0005576=Reactome:REACT_22436, GO:0016358=PMID:16491079, GO:0009755=PMID:16511605, GO:0042322=PMID:18329818, GO:0007186=PMID:16511605, GO:0016608=PMID:16511605, GO:0001937=PMID:15572208, GO:0008154=PMID:15232612, GO:0050728=PMID:15232612, GO:0016525=PMID:15572208, GO:0005788=Reactome:REACT_19329, GO:0044267=Reactome:REACT_17015, GO:0034774=Reactome:REACT_19170} Q9UBU3 Appetite-regulating hormone protein 20130413 {GO:0008343=ISS, GO:0060124=IDA, GO:0030424=IDA, GO:0043627=IDA, GO:0051216=NAS, GO:0061098=IMP, GO:0032691=IDA, GO:0032100=ISS, GO:0060399=IC, GO:0045409=IDA, GO:0007204=ISS, GO:0001696=IEA, GO:0005615=IDA, GO:0000187=IMP, GO:0046697=IDA, GO:0005737=IEA, GO:0030296=IMP, GO:0040013=IEA, GO:0042127=IDA, GO:0006006=NAS, GO:0051461=IDA, GO:0030252=TAS, GO:0032024=ISS, GO:0031768=TAS, GO:0009725=IDA, GO:0040018=IC, GO:0046676=IEA, GO:0046010=IDA, GO:0051464=IDA, GO:0043400=NAS, GO:0051965=IDA, GO:0043066=IDA, GO:0001664=ISS, GO:0042536=IDA, GO:0060079=IEA, GO:0005576=TAS, GO:0016358=IDA, GO:0009755=TAS, GO:0042322=IDA, GO:0007186=TAS, GO:0016608=TAS, GO:0001937=IDA, GO:0008154=IDA, GO:0050728=IDA, GO:0016525=NAS, GO:0005788=TAS, GO:0044267=TAS, GO:0034774=TAS} G-protein coupled receptor signaling pathway, actin polymerization or depolymerization, activation of MAPK activity, adult feeding behavior, cartilage development, cellular protein metabolic process, cortisol secretion, decidualization, dendrite development, elevation of cytosolic calcium ion concentration, gastric acid secretion, glucose metabolic process, growth hormone secretion, hormone-mediated signaling pathway, negative regulation of angiogenesis, negative regulation of apoptotic process, negative regulation of circadian sleep/wake cycle, REM sleep, negative regulation of endothelial cell proliferation, negative regulation of inflammatory response, negative regulation of insulin secretion, negative regulation of interleukin-1 beta production, negative regulation of interleukin-6 biosynthetic process, negative regulation of locomotion, negative regulation of tumor necrosis factor biosynthetic process, positive regulation of appetite, positive regulation of circadian sleep/wake cycle, non-REM sleep, positive regulation of corticotropin secretion, positive regulation of cortisol secretion, positive regulation of growth hormone receptor signaling pathway, positive regulation of growth hormone secretion, positive regulation of insulin secretion, positive regulation of multicellular organism growth, positive regulation of protein tyrosine kinase activity, positive regulation of synapse assembly, regulation of cell proliferation, regulation of excitatory postsynaptic membrane potential, response to estrogen stimulus, response to hormone stimulus axon, cytoplasm, endoplasmic reticulum lumen, extracellular region, extracellular space, secretory granule lumen G-protein coupled receptor binding, ghrelin receptor binding, growth hormone-releasing hormone activity, protein tyrosine kinase activator activity Human GHSR Reactome UniProtKB {GO:0008343=GO_REF:0000024, GO:0043005=PMID:12890514, GO:0005886=Reactome:REACT_22436, GO:0032691=PMID:15232612, GO:0032100=GO_REF:0000024, GO:0045409=PMID:15232612, GO:0016520=PMID:8688086, GO:0032094=GO_REF:0000019, GO:0046697=PMID:17494105, GO:0045923=GO_REF:0000019, GO:0001616=PMID:8688086, GO:0030252=PMID:16511605, GO:0009725=PMID:15232612, GO:0040018=PMID:16511605, GO:0046676=GO_REF:0000019, GO:0051963=GO_REF:0000019, GO:0032869=GO_REF:0000019, GO:0009986=PMID:8688086, GO:0004930=PMID:8688086, GO:0042536=PMID:15232612, GO:0009755=PMID:8688086, GO:0007186=PMID:8688086, GO:0008154=PMID:15232612, GO:0043568=GO_REF:0000019, GO:0050728=PMID:15232612, GO:0045121=PMID:15232612, GO:0016021=GO_REF:0000037, GO:0017046=GO_REF:0000019, GO:0043134=GO_REF:0000019} Q92847 Growth hormone secretagogue receptor type 1 protein 20101028 {GO:0008343=ISS, GO:0043005=IDA, GO:0005886=TAS, GO:0032691=IDA, GO:0032100=ISS, GO:0045409=IDA, GO:0016520=IDA, GO:0032094=IEA, GO:0046697=IDA, GO:0045923=IEA, GO:0001616=IDA, GO:0030252=TAS, GO:0009725=IDA, GO:0040018=IMP, GO:0046676=IEA, GO:0051963=IEA, GO:0032869=IEA, GO:0009986=IDA, GO:0004930=IDA, GO:0042536=IDA, GO:0009755=IDA, GO:0007186=IDA, GO:0008154=IDA, GO:0043568=IEA, GO:0050728=IDA, GO:0045121=IDA, GO:0016021=IEA, GO:0017046=IEA, GO:0043134=IEA} G-protein coupled receptor signaling pathway, actin polymerization or depolymerization, adult feeding behavior, cellular response to insulin stimulus, decidualization, growth hormone secretion, hormone-mediated signaling pathway, negative regulation of inflammatory response, negative regulation of insulin secretion, negative regulation of interleukin-1 beta production, negative regulation of interleukin-6 biosynthetic process, negative regulation of tumor necrosis factor biosynthetic process, positive regulation of appetite, positive regulation of fatty acid metabolic process, positive regulation of insulin-like growth factor receptor signaling pathway, positive regulation of multicellular organism growth, regulation of hindgut contraction, regulation of synapse assembly, response to food, response to hormone stimulus cell surface, integral to membrane, membrane raft, neuron projection, plasma membrane G-protein coupled receptor activity, growth hormone secretagogue receptor activity, growth hormone-releasing hormone receptor activity, peptide hormone binding Human GIF UniProtKB UniProtKB {GO:0005902=PMID:8886952, GO:0016324=PMID:8886952, GO:0015889=PMID:15738392, GO:0009235=GO_REF:0000033, GO:0031419=PMID:14695536, GO:0005615=PMID:14695536, GO:0005768=PMID:8886952, GO:0006824=GO_REF:0000037} P27352 Gastric intrinsic factor protein 20090814 {GO:0005902=IDA, GO:0016324=IDA, GO:0015889=IMP, GO:0009235=IBA, GO:0031419=IDA, GO:0005615=IDA, GO:0005768=IDA, GO:0006824=IEA} cobalamin metabolic process, cobalamin transport, cobalt ion transport apical plasma membrane, endosome, extracellular space, microvillus cobalamin binding Human GIGYF1 ENSEMBL UniProtKB {GO:0048009=GO_REF:0000019} O75420 PERQ amino acid-rich with GYF domain-containing protein 1 protein 20130413 {GO:0048009=IEA} insulin-like growth factor receptor signaling pathway Human Ensembl:ENSMUSP00000031727 GIGYF2 MGI UniProtKB {GO:0017148=PMID:22751931, GO:0007631=GO_REF:0000019, GO:0008344=GO_REF:0000019, GO:0008219=GO_REF:0000037, GO:0021522=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0000084=GO_REF:0000019, GO:0048873=GO_REF:0000019, GO:0035264=GO_REF:0000019, GO:0050881=GO_REF:0000019, GO:0050885=GO_REF:0000019, GO:0048009=GO_REF:0000019, GO:0044267=GO_REF:0000019} Q6Y7W6 PERQ amino acid-rich with GYF domain-containing protein 2 protein 20130211 {GO:0017148=IMP, GO:0007631=IEA, GO:0008344=IEA, GO:0008219=IEA, GO:0021522=IEA, GO:0009791=IEA, GO:0000084=IEA, GO:0048873=IEA, GO:0035264=IEA, GO:0050881=IEA, GO:0050885=IEA, GO:0048009=IEA, GO:0044267=IEA} S phase of mitotic cell cycle, adult locomotory behavior, cell death, cellular protein metabolic process, feeding behavior, homeostasis of number of cells within a tissue, insulin-like growth factor receptor signaling pathway, multicellular organism growth, musculoskeletal movement, negative regulation of translation, neuromuscular process controlling balance, post-embryonic development, spinal cord motor neuron differentiation Human GIMAP1 UniProtKB UniProtKB {GO:0000139=GO_REF:0000039, GO:0030217=GO_REF:0000019, GO:0030183=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0005525=GO_REF:0000019} Q8WWP7 GTPase IMAP family member 1 protein 20130413 {GO:0000139=IEA, GO:0030217=IEA, GO:0030183=IEA, GO:0005789=IEA, GO:0016021=IEA, GO:0005525=IEA} B cell differentiation, T cell differentiation Golgi membrane, endoplasmic reticulum membrane, integral to membrane GTP binding Human UniProtKB-SubCell:SL-0097 GIMAP4 HPA UniProtKB {GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005525=GO_REF:0000037, GO:0005829=GO_REF:0000039} Q9NUV9 GTPase IMAP family member 4 protein 20111111 {GO:0005730=IDA, GO:0005634=IDA, GO:0005525=IEA, GO:0005829=IEA} cytosol, nucleolus, nucleus GTP binding NOT Human GIMAP5 UniProtKB UniProtKB {GO:0046902=GO_REF:0000019, GO:0032831=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0050995=GO_REF:0000019, GO:0001659=GO_REF:0000019, GO:0050868=GO_REF:0000019, GO:0002729=GO_REF:0000019, GO:0010524=GO_REF:0000019, GO:0045588=GO_REF:0000019, GO:0005741=GO_REF:0000039, GO:0005525=GO_REF:0000037, GO:0005764=GO_REF:0000039, GO:0045838=GO_REF:0000019, GO:0002925=GO_REF:0000019, GO:0030217=GO_REF:0000019, GO:0045019=GO_REF:0000019, GO:0045954=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0043011=GO_REF:0000019, GO:0043029=GO_REF:0000019, GO:0032689=GO_REF:0000019} Q96F15 GTPase IMAP family member 5 protein 20130413 {GO:0046902=IEA, GO:0032831=IEA, GO:0043066=IEA, GO:0050995=IEA, GO:0001659=IEA, GO:0050868=IEA, GO:0002729=IEA, GO:0010524=IEA, GO:0045588=IEA, GO:0005741=IEA, GO:0005525=IEA, GO:0005764=IEA, GO:0045838=IEA, GO:0002925=IEA, GO:0030217=IEA, GO:0045019=IEA, GO:0045954=IEA, GO:0016021=IEA, GO:0043011=IEA, GO:0043029=IEA, GO:0032689=IEA} T cell differentiation, T cell homeostasis, myeloid dendritic cell differentiation, negative regulation of T cell activation, negative regulation of apoptotic process, negative regulation of interferon-gamma production, negative regulation of lipid catabolic process, negative regulation of nitric oxide biosynthetic process, positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation, positive regulation of calcium ion transport into cytosol, positive regulation of gamma-delta T cell differentiation, positive regulation of humoral immune response mediated by circulating immunoglobulin, positive regulation of membrane potential, positive regulation of natural killer cell cytokine production, positive regulation of natural killer cell mediated cytotoxicity, regulation of mitochondrial membrane permeability, temperature homeostasis integral to membrane, lysosome, mitochondrial outer membrane GTP binding Human UniProtKB-SubCell:SL-0158 GIMAP6 UniProtKB UniProtKB {GO:0005525=GO_REF:0000037} Q6P9H5 GTPase IMAP family member 6 protein 20130413 {GO:0005525=IEA} GTP binding Human UniProtKB-KW:KW-0342 GIMAP7 UniProtKB UniProtKB {GO:0005525=GO_REF:0000037} Q8NHV1 GTPase IMAP family member 7 protein 20130413 {GO:0005525=IEA} GTP binding Human UniProtKB-KW:KW-0342 GIMAP8 HPA UniProtKB {GO:0005739=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000039, GO:0005783=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005525=GO_REF:0000037} Q8ND71 GTPase IMAP family member 8 protein 20090616 {GO:0005739=IEA, GO:0005737=IDA, GO:0005794=IEA, GO:0005783=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005525=IEA} Golgi apparatus, cytoplasm, endoplasmic reticulum, mitochondrion, nucleolus, nucleus GTP binding Human GIN1 InterPro UniProtKB {GO:0015074=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q9NXP7 Gypsy retrotransposon integrase-like protein 1 protein 20130413 {GO:0015074=IEA, GO:0003676=IEA} DNA integration nucleic acid binding Human InterPro:IPR001584 GINS1 Reactome UniProtKB {GO:0000084=Reactome:REACT_899, GO:0006271=Reactome:REACT_932, GO:0005737=PMID:10942595, GO:0001833=GO_REF:0000019, GO:0005654=Reactome:REACT_6747, GO:0005634=PMID:10942595, GO:0000278=Reactome:REACT_152} Q14691 DNA replication complex GINS protein PSF1 protein 20130213 {GO:0000084=TAS, GO:0006271=TAS, GO:0005737=IDA, GO:0001833=IEA, GO:0005654=TAS, GO:0005634=IDA, GO:0000278=TAS} DNA strand elongation involved in DNA replication, S phase of mitotic cell cycle, inner cell mass cell proliferation, mitotic cell cycle cytoplasm, nucleoplasm, nucleus Human GINS2 IntAct UniProtKB {GO:0005515=PMID:17525332, GO:0000084=Reactome:REACT_899, GO:0006260=GO_REF:0000002, GO:0006271=Reactome:REACT_932, GO:0005654=Reactome:REACT_6747, GO:0005634=GO_REF:0000002, GO:0000278=Reactome:REACT_152} Q9Y248 DNA replication complex GINS protein PSF2 protein 20130415 {GO:0005515=IPI, GO:0000084=TAS, GO:0006260=IEA, GO:0006271=TAS, GO:0005654=TAS, GO:0005634=IEA, GO:0000278=TAS} DNA replication, DNA strand elongation involved in DNA replication, S phase of mitotic cell cycle, mitotic cell cycle nucleoplasm, nucleus protein binding Human UniProtKB:O96017 GINS3 UniProtKB UniProtKB {GO:0006260=GO_REF:0000037, GO:0005634=GO_REF:0000039} Q9BRX5 DNA replication complex GINS protein PSF3 protein 20130413 {GO:0006260=IEA, GO:0005634=IEA} DNA replication nucleus Human UniProtKB-SubCell:SL-0191 GINS4 Reactome UniProtKB {GO:0000084=Reactome:REACT_899, GO:0006260=GO_REF:0000038, GO:0006271=Reactome:REACT_932, GO:0005737=GO_REF:0000039, GO:0005654=Reactome:REACT_6747, GO:0005634=GO_REF:0000019, GO:0000278=Reactome:REACT_152} Q9BRT9 DNA replication complex GINS protein SLD5 protein 20130213 {GO:0000084=TAS, GO:0006260=IEA, GO:0006271=TAS, GO:0005737=IEA, GO:0005654=TAS, GO:0005634=IEA, GO:0000278=TAS} DNA replication, DNA strand elongation involved in DNA replication, S phase of mitotic cell cycle, mitotic cell cycle cytoplasm, nucleoplasm, nucleus Human GIP Reactome UniProtKB {GO:0055123=GO_REF:0000019, GO:0014070=GO_REF:0000019, GO:0008344=GO_REF:0000019, GO:0043434=GO_REF:0000019, GO:0070328=GO_REF:0000019, GO:0060291=GO_REF:0000019, GO:0048678=GO_REF:0000019, GO:0042594=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0043950=GO_REF:0000019, GO:0032024=GO_REF:0000019, GO:0007613=GO_REF:0000019, GO:0043200=GO_REF:0000019, GO:0035640=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0070094=GO_REF:0000019, GO:0010269=GO_REF:0000019, GO:0005576=Reactome:REACT_23981, GO:0019233=GO_REF:0000019, GO:0010828=GO_REF:0000019, GO:0009749=GO_REF:0000019, GO:0007165=PMID:2890159, GO:0050796=Reactome:REACT_23974, GO:0005179=GO_REF:0000037, GO:0031018=GO_REF:0000019, GO:0005788=Reactome:REACT_23843, GO:0044267=Reactome:REACT_17015, GO:0034774=Reactome:REACT_23868} P09681 Gastric inhibitory polypeptide protein 20130228 {GO:0055123=IEA, GO:0014070=IEA, GO:0008344=IEA, GO:0043434=IEA, GO:0070328=IEA, GO:0060291=IEA, GO:0048678=IEA, GO:0042594=IEA, GO:0043025=IEA, GO:0043950=IEA, GO:0032024=IEA, GO:0007613=IEA, GO:0043200=IEA, GO:0035640=IEA, GO:0007565=IEA, GO:0042493=IEA, GO:0070094=IEA, GO:0010269=IEA, GO:0005576=TAS, GO:0019233=IEA, GO:0010828=IEA, GO:0009749=IEA, GO:0007165=TAS, GO:0050796=TAS, GO:0005179=IEA, GO:0031018=IEA, GO:0005788=TAS, GO:0044267=TAS, GO:0034774=TAS} adult locomotory behavior, cellular protein metabolic process, digestive system development, endocrine pancreas development, exploration behavior, female pregnancy, long-term synaptic potentiation, memory, positive regulation of cAMP-mediated signaling, positive regulation of glucagon secretion, positive regulation of glucose transport, positive regulation of insulin secretion, regulation of insulin secretion, response to amino acid stimulus, response to axon injury, response to drug, response to glucose stimulus, response to organic cyclic compound, response to peptide hormone stimulus, response to selenium ion, response to starvation, sensory perception of pain, signal transduction, triglyceride homeostasis endoplasmic reticulum lumen, extracellular region, neuronal cell body, secretory granule lumen hormone activity Human GIPC1 BHF-UCL UniProtKB {GO:0005515=PMID:9770488, GO:0007268=GO_REF:0000024, GO:0030139=GO_REF:0000019, GO:0032435=GO_REF:0000024, GO:0006605=GO_REF:0000024, GO:0042803=GO_REF:0000024, GO:0005829=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0031647=GO_REF:0000024, GO:0043197=GO_REF:0000024, GO:0043198=GO_REF:0000024, GO:0048167=GO_REF:0000024, GO:0005938=PMID:12857860, GO:0030511=GO_REF:0000024, GO:0012506=GO_REF:0000024, GO:0005102=PMID:15459234, GO:0003779=GO_REF:0000024, GO:0030165=GO_REF:0000019, GO:0014047=GO_REF:0000024, GO:0008021=GO_REF:0000024, GO:0044445=GO_REF:0000019, GO:0005903=GO_REF:0000019, GO:0016020=GO_REF:0000024, GO:0007186=PMID:9770488, GO:0043542=GO_REF:0000024, GO:0016023=PMID:12857860, GO:0017022=GO_REF:0000024} O14908 PDZ domain-containing protein GIPC1 protein 20080820 {GO:0005515=IPI, GO:0007268=ISS, GO:0030139=IEA, GO:0032435=ISS, GO:0006605=ISS, GO:0042803=ISS, GO:0005829=ISS, GO:0005737=ISS, GO:0031647=ISS, GO:0043197=ISS, GO:0043198=ISS, GO:0048167=ISS, GO:0005938=IDA, GO:0030511=ISS, GO:0012506=ISS, GO:0005102=IPI, GO:0003779=ISS, GO:0030165=IEA, GO:0014047=ISS, GO:0008021=ISS, GO:0044445=IEA, GO:0005903=IEA, GO:0016020=ISS, GO:0007186=NAS, GO:0043542=ISS, GO:0016023=IDA, GO:0017022=ISS} G-protein coupled receptor signaling pathway, endothelial cell migration, glutamate secretion, negative regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of transforming growth factor beta receptor signaling pathway, protein targeting, regulation of protein stability, regulation of synaptic plasticity, synaptic transmission brush border, cell cortex, cytoplasm, cytoplasmic membrane-bounded vesicle, cytosol, cytosolic part, dendritic shaft, dendritic spine, endocytic vesicle, membrane, synaptic vesicle, vesicle membrane PDZ domain binding, actin binding, myosin binding, protein binding, protein homodimerization activity, receptor binding Human UniProtKB:Q9Z0G0 GIPC2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q8TF65 PDZ domain-containing protein GIPC2 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 GIPC3 null null {} null null null null {} null null null GIPR Reactome UniProtKB {GO:0007190=PMID:7589426, GO:0016519=GO_REF:0000002, GO:0005886=Reactome:REACT_22268, GO:0007584=PMID:7556958, GO:0006091=PMID:7556958, GO:0016021=GO_REF:0000037, GO:0007166=PMID:7556958, GO:0004888=PMID:7556958} P48546 Gastric inhibitory polypeptide receptor protein 20090511 {GO:0007190=TAS, GO:0016519=IEA, GO:0005886=TAS, GO:0007584=TAS, GO:0006091=TAS, GO:0016021=IEA, GO:0007166=TAS, GO:0004888=TAS} activation of adenylate cyclase activity, cell surface receptor signaling pathway, generation of precursor metabolites and energy, response to nutrient integral to membrane, plasma membrane gastric inhibitory peptide receptor activity, transmembrane signaling receptor activity Human GIT1 HPA UniProtKB {GO:0005515=PMID:21295525, GO:0008060=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0008277=PMID:9826657, GO:0032312=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0005925=GO_REF:0000052} Q9Y2X7 ARF GTPase-activating protein GIT1 protein 20101115 {GO:0005515=IPI, GO:0008060=IEA, GO:0005737=IDA, GO:0008277=TAS, GO:0032312=IEA, GO:0008270=IEA, GO:0005925=IDA} regulation of ARF GTPase activity, regulation of G-protein coupled receptor protein signaling pathway cytoplasm, focal adhesion ARF GTPase activator activity, protein binding, zinc ion binding Human GIT2 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0008060=GO_REF:0000002, GO:0008277=PMID:10896954, GO:0032312=GO_REF:0000002, GO:0005654=PMID:10942595, GO:0008270=GO_REF:0000002} Q14161 ARF GTPase-activating protein GIT2 protein 20130415 {GO:0005515=IPI, GO:0008060=IEA, GO:0008277=TAS, GO:0032312=IEA, GO:0005654=IDA, GO:0008270=IEA} regulation of ARF GTPase activity, regulation of G-protein coupled receptor protein signaling pathway nucleoplasm ARF GTPase activator activity, protein binding, zinc ion binding Human UniProtKB:Q9Y6K9 GJA1 GOC UniProtKB {GO:0005515=PMID:15709751, GO:0017124=GO_REF:0000019, GO:0045732=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:2000810=GO_REF:0000019, GO:0005886=GO_REF:0000024, GO:0015075=PMID:1696265, GO:0007267=PMID:7715640, GO:0043434=GO_REF:0000019, GO:0005741=GO_REF:0000019, GO:0010232=GO_REF:0000019, GO:0016264=Reactome:REACT_9509, GO:0005764=GO_REF:0000019, GO:0051259=GO_REF:0000019, GO:0005916=GO_REF:0000019, GO:0007507=GO_REF:0000002, GO:0034220=PMID:1696265, GO:0006936=PMID:7715640, GO:0014704=GO_REF:0000024, GO:0051924=GO_REF:0000019, GO:0006810=PMID:1696265, GO:0004871=PMID:12761501, GO:0043123=PMID:12761501, GO:0010644=PMID:16790700, GO:0009268=GO_REF:0000019, GO:0005243=PMID:23348765, GO:0005794=GO_REF:0000024, GO:0005771=GO_REF:0000019, GO:0006915=GO_REF:0000019, GO:0030165=GO_REF:0000019, GO:0007165=PMID:12761501, GO:0000139=Reactome:REACT_10110, GO:0005887=PMID:15709751, GO:0030660=Reactome:REACT_10110, GO:0048812=GO_REF:0000019, GO:0005789=Reactome:REACT_9473, GO:0086014=PMID:23348765, GO:0005921=PMID:23348765, GO:0015867=GO_REF:0000019, GO:0045121=GO_REF:0000024, GO:0005922=GO_REF:0000002, GO:0016044=Reactome:REACT_11123, GO:0005769=GO_REF:0000019} P17302 Gap junction alpha-1 protein protein 20130413 {GO:0005515=IPI, GO:0017124=IEA, GO:0045732=IEA, GO:0008285=IEA, GO:2000810=IEA, GO:0005886=ISS, GO:0015075=TAS, GO:0007267=TAS, GO:0043434=IEA, GO:0005741=IEA, GO:0010232=IEA, GO:0016264=TAS, GO:0005764=IEA, GO:0051259=IEA, GO:0005916=IEA, GO:0007507=IEA, GO:0034220=TAS, GO:0006936=TAS, GO:0014704=ISS, GO:0051924=IEA, GO:0006810=TAS, GO:0004871=IMP, GO:0043123=IMP, GO:0010644=IDA, GO:0009268=IEA, GO:0005243=IDA, GO:0005794=ISS, GO:0005771=IEA, GO:0006915=IEA, GO:0030165=IEA, GO:0007165=IMP, GO:0000139=TAS, GO:0005887=TAS, GO:0030660=TAS, GO:0048812=IEA, GO:0005789=TAS, GO:0086014=TAS, GO:0005921=IDA, GO:0015867=IEA, GO:0045121=ISS, GO:0005922=IEA, GO:0016044=TAS, GO:0005769=IEA} ATP transport, apoptotic process, cell communication by electrical coupling, cell-cell signaling, cellular membrane organization, gap junction assembly, heart development, ion transmembrane transport, muscle contraction, negative regulation of cell proliferation, neuron projection morphogenesis, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of protein catabolic process, protein oligomerization, regulation of atrial cardiac muscle cell action potential, regulation of calcium ion transport, regulation of tight junction assembly, response to pH, response to peptide hormone stimulus, signal transduction, transport, vascular transport Golgi apparatus, Golgi membrane, Golgi-associated vesicle membrane, connexon complex, early endosome, endoplasmic reticulum membrane, fascia adherens, gap junction, integral to plasma membrane, intercalated disc, lysosome, membrane raft, mitochondrial outer membrane, multivesicular body, plasma membrane PDZ domain binding, SH3 domain binding, gap junction channel activity, ion transmembrane transporter activity, protein binding, signal transducer activity Human GJA10 Reactome UniProtKB {GO:0005243=Reactome:REACT_17030, GO:0005886=Reactome:REACT_17030, GO:0050908=GO_REF:0000019, GO:0007276=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0005922=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007416=GO_REF:0000019} Q969M2 Gap junction alpha-10 protein protein 20130213 {GO:0005243=TAS, GO:0005886=TAS, GO:0050908=IEA, GO:0007276=IEA, GO:0007268=TAS, GO:0005922=IEA, GO:0016021=IEA, GO:0007416=IEA} detection of light stimulus involved in visual perception, gamete generation, synapse assembly, synaptic transmission connexon complex, integral to membrane, plasma membrane gap junction channel activity Human GJA3 PINC UniProtKB {GO:0005243=GO_REF:0000002, GO:0007267=PMID:9413992, GO:0006810=PMID:9413992, GO:0005922=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007601=PMID:10205266} Q9Y6H8 Gap junction alpha-3 protein protein 20030904 {GO:0005243=IEA, GO:0007267=TAS, GO:0006810=NAS, GO:0005922=IEA, GO:0016021=IEA, GO:0007601=TAS} cell-cell signaling, transport, visual perception connexon complex, integral to membrane gap junction channel activity Human GJA4 ENSEMBL UniProtKB {GO:0001568=GO_REF:0000019, GO:0005887=PMID:7680674, GO:0007043=PMID:7680674, GO:0006810=PMID:7680674, GO:0007267=GO_REF:0000019, GO:0005921=PMID:7680674, GO:0048265=GO_REF:0000019, GO:0006816=GO_REF:0000019, GO:0005922=GO_REF:0000019, GO:0016021=GO_REF:0000038} Q5JW71 Gap junction alpha-4 protein protein 20130413 {GO:0001568=IEA, GO:0005887=TAS, GO:0007043=TAS, GO:0006810=TAS, GO:0007267=IEA, GO:0005921=TAS, GO:0048265=IEA, GO:0006816=IEA, GO:0005922=IEA, GO:0016021=IEA} blood vessel development, calcium ion transport, cell-cell junction assembly, cell-cell signaling, response to pain, transport connexon complex, gap junction, integral to membrane, integral to plasma membrane Human Ensembl:ENSRNOP00000019246 GJA5 BHF-UCL UniProtKB {GO:0035922=GO_REF:0000019, GO:0003161=GO_REF:0000019, GO:0086053=PMID:22247482, GO:0003283=PMID:22199024, GO:0003284=GO_REF:0000019, GO:0048844=GO_REF:0000024, GO:0055077=PMID:23348765, GO:0003281=PMID:22199024, GO:0060307=GO_REF:0000019, GO:0030326=GO_REF:0000019, GO:0016264=PMID:22247482, GO:0086091=GO_REF:0000019, GO:0086075=PMID:16790700, GO:1900825=GO_REF:0000019, GO:0060371=PMID:23348765, GO:0042312=GO_REF:0000019, GO:0060373=GO_REF:0000019, GO:0086069=PMID:22247482, GO:0014704=PMID:23348765, GO:0086005=GO_REF:0000019, GO:0003294=GO_REF:0000019, GO:0035050=GO_REF:0000019, GO:0060413=GO_REF:0000019, GO:0060412=GO_REF:0000019, GO:0003193=PMID:22199024, GO:0003174=PMID:22199024, GO:0001525=PMID:11866539, GO:0086064=PMID:16790700, GO:0003151=PMID:22199024, GO:0003071=GO_REF:0000019, GO:0001501=GO_REF:0000019, GO:1900133=GO_REF:0000019, GO:0005887=PMID:22247482, GO:0086077=PMID:22247482, GO:0055117=PMID:16790700, GO:0086014=PMID:23348765, GO:0005921=PMID:23348765, GO:0005922=PMID:22247482, GO:0086015=GO_REF:0000019} P36382 Gap junction alpha-5 protein protein 20130130 {GO:0035922=IEA, GO:0003161=IEA, GO:0086053=IMP, GO:0003283=IMP, GO:0003284=IEA, GO:0048844=ISS, GO:0055077=IDA, GO:0003281=IMP, GO:0060307=IEA, GO:0030326=IEA, GO:0016264=IDA, GO:0086091=IEA, GO:0086075=IMP, GO:1900825=IEA, GO:0060371=IMP, GO:0042312=IEA, GO:0060373=IEA, GO:0086069=IMP, GO:0014704=TAS, GO:0086005=IEA, GO:0003294=IEA, GO:0035050=IEA, GO:0060413=IEA, GO:0060412=IEA, GO:0003193=IMP, GO:0003174=IMP, GO:0001525=IEP, GO:0086064=IDA, GO:0003151=IMP, GO:0003071=IEA, GO:0001501=IEA, GO:1900133=IEA, GO:0005887=IDA, GO:0086077=IDA, GO:0055117=IMP, GO:0086014=IMP, GO:0005921=IDA, GO:0005922=IDA, GO:0086015=IEA} AV node cell to bundle of His cell communication by electrical coupling, angiogenesis, artery morphogenesis, atrial septum development, atrial septum morphogenesis, atrial ventricular junction remodeling, bundle of His cell to Purkinje myocyte communication, cardiac conduction system development, cell communication by electrical coupling involved in cardiac conduction, embryonic heart tube development, embryonic limb morphogenesis, foramen ovale closure, gap junction assembly, mitral valve development, outflow tract morphogenesis, pulmonary valve formation, regulation of SA node cell action potential, regulation of atrial cardiac muscle cell action potential, regulation of atrial cardiac muscle cell membrane depolarization, regulation of cardiac muscle contraction, regulation of heart rate by cardiac conduction, regulation of membrane depolarization involved in regulation of cardiac muscle cell action potential, regulation of renin secretion into blood stream, regulation of vasodilation, regulation of ventricular cardiac muscle cell action potential, regulation of ventricular cardiac muscle cell membrane depolarization, regulation of ventricular cardiac muscle cell membrane repolarization, renal system process involved in regulation of systemic arterial blood pressure, septum primum development, skeletal system development, ventricular septum development, ventricular septum morphogenesis connexon complex, gap junction, integral to plasma membrane, intercalated disc gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling, gap junction channel activity involved in cardiac conduction electrical coupling, gap junction hemi-channel activity Human GJA8 PINC UniProtKB {GO:0005887=PMID:7796604, GO:0002088=GO_REF:0000019, GO:0006810=PMID:7796604, GO:0007267=GO_REF:0000019, GO:0051260=GO_REF:0000019, GO:0005922=GO_REF:0000019, GO:0007601=PMID:9497259, GO:0015267=PMID:7796604} P48165 Gap junction alpha-8 protein protein 20030904 {GO:0005887=TAS, GO:0002088=IEA, GO:0006810=TAS, GO:0007267=IEA, GO:0051260=IEA, GO:0005922=IEA, GO:0007601=TAS, GO:0015267=TAS} cell-cell signaling, lens development in camera-type eye, protein homooligomerization, transport, visual perception connexon complex, integral to plasma membrane channel activity Human GJA9 UniProtKB UniProtKB {GO:0007154=GO_REF:0000002, GO:0005922=GO_REF:0000002, GO:0016021=GO_REF:0000037} P57773 Gap junction alpha-9 protein protein 20130413 {GO:0007154=IEA, GO:0005922=IEA, GO:0016021=IEA} cell communication connexon complex, integral to membrane Human UniProtKB-KW:KW-0812 GJB1 Reactome UniProtKB {GO:0005243=GO_REF:0000019, GO:0005783=GO_REF:0000019, GO:0007267=PMID:8266101, GO:0016264=Reactome:REACT_9509, GO:0051259=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0007399=PMID:8266101, GO:0007154=GO_REF:0000002, GO:0006810=PMID:2875078, GO:0005789=Reactome:REACT_9494, GO:0005922=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0015868=GO_REF:0000019, GO:0016044=Reactome:REACT_11123} P08034 Gap junction beta-1 protein protein 20130213 {GO:0005243=IEA, GO:0005783=IEA, GO:0007267=TAS, GO:0016264=TAS, GO:0051259=IEA, GO:0042803=IEA, GO:0007399=TAS, GO:0007154=IEA, GO:0006810=TAS, GO:0005789=TAS, GO:0005922=IEA, GO:0016021=IEA, GO:0015868=IEA, GO:0016044=TAS} cell communication, cell-cell signaling, cellular membrane organization, gap junction assembly, nervous system development, protein oligomerization, purine ribonucleotide transport, transport connexon complex, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane gap junction channel activity, protein homodimerization activity Human GJB2 Reactome UniProtKB {GO:0030539=GO_REF:0000019, GO:0005793=Reactome:REACT_21353, GO:0005243=GO_REF:0000019, GO:0005886=Reactome:REACT_21353, GO:0007605=GO_REF:0000037, GO:0006810=PMID:1324944, GO:0007267=GO_REF:0000019, GO:0005922=GO_REF:0000002, GO:0016264=Reactome:REACT_9509, GO:0016021=GO_REF:0000037, GO:0016328=GO_REF:0000019, GO:0016044=Reactome:REACT_11123} P29033 Gap junction beta-2 protein protein 20130213 {GO:0030539=IEA, GO:0005793=TAS, GO:0005243=IEA, GO:0005886=TAS, GO:0007605=IEA, GO:0006810=TAS, GO:0007267=IEA, GO:0005922=IEA, GO:0016264=TAS, GO:0016021=IEA, GO:0016328=IEA, GO:0016044=TAS} cell-cell signaling, cellular membrane organization, gap junction assembly, male genitalia development, sensory perception of sound, transport connexon complex, endoplasmic reticulum-Golgi intermediate compartment, integral to membrane, lateral plasma membrane, plasma membrane gap junction channel activity Human GJB3 UniProtKB UniProtKB {GO:0005243=PMID:9704026, GO:0005737=GO_REF:0000019, GO:0007154=GO_REF:0000029, GO:0007605=GO_REF:0000019, GO:0005921=PMID:9704026, GO:0043588=GO_REF:0000019, GO:0005922=GO_REF:0000002, GO:0001890=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0001701=GO_REF:0000019} O75712 Gap junction beta-3 protein protein 20021104 {GO:0005243=NAS, GO:0005737=IEA, GO:0007154=NAS, GO:0007605=IEA, GO:0005921=NAS, GO:0043588=IEA, GO:0005922=IEA, GO:0001890=IEA, GO:0016021=IEA, GO:0001701=IEA} cell communication, in utero embryonic development, placenta development, sensory perception of sound, skin development connexon complex, cytoplasm, gap junction, integral to membrane gap junction channel activity Human GJB5 PINC UniProtKB {GO:0007154=GO_REF:0000002, GO:0008544=PMID:9843209, GO:0060713=GO_REF:0000019, GO:0060708=GO_REF:0000019, GO:0005922=GO_REF:0000002, GO:0016021=GO_REF:0000037} O95377 Gap junction beta-5 protein protein 20030904 {GO:0007154=IEA, GO:0008544=TAS, GO:0060713=IEA, GO:0060708=IEA, GO:0005922=IEA, GO:0016021=IEA} cell communication, epidermis development, labyrinthine layer morphogenesis, spongiotrophoblast differentiation connexon complex, integral to membrane Human GJB6 HPA UniProtKB {GO:0042471=GO_REF:0000019, GO:0007154=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0007605=GO_REF:0000019, GO:0005922=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0043231=GO_REF:0000052} O95452 Gap junction beta-6 protein protein 20101115 {GO:0042471=IEA, GO:0007154=IEA, GO:0005886=IDA, GO:0007605=IEA, GO:0005922=IEA, GO:0016021=IEA, GO:0043231=IDA} cell communication, ear morphogenesis, sensory perception of sound connexon complex, integral to membrane, intracellular membrane-bounded organelle, plasma membrane Human GJB7 UniProtKB UniProtKB {GO:0007154=GO_REF:0000002, GO:0005922=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q6PEY0 Gap junction beta-7 protein protein 20130413 {GO:0007154=IEA, GO:0005922=IEA, GO:0016021=IEA} cell communication connexon complex, integral to membrane Human UniProtKB-KW:KW-0812 GJC1 BHF-UCL UniProtKB {GO:0005243=GO_REF:0000019, GO:0005886=Reactome:REACT_16989, GO:0007268=Reactome:REACT_13685, GO:0016264=Reactome:REACT_9509, GO:0048738=GO_REF:0000019, GO:0007154=GO_REF:0000002, GO:0006936=PMID:7966354, GO:0014704=PMID:23348765, GO:0005789=Reactome:REACT_9410, GO:0006810=PMID:7966354, GO:0007043=PMID:7966354, GO:0086014=PMID:23348765, GO:0005921=PMID:7966354, GO:0005922=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0048468=GO_REF:0000019, GO:0005216=GO_REF:0000019, GO:0007601=GO_REF:0000019, GO:0001570=GO_REF:0000019, GO:0016044=Reactome:REACT_11123} P36383 Gap junction gamma-1 protein protein 20130130 {GO:0005243=IEA, GO:0005886=TAS, GO:0007268=TAS, GO:0016264=TAS, GO:0048738=IEA, GO:0007154=IEA, GO:0006936=TAS, GO:0014704=TAS, GO:0005789=TAS, GO:0006810=NAS, GO:0007043=TAS, GO:0086014=TAS, GO:0005921=TAS, GO:0005922=IEA, GO:0016021=IEA, GO:0048468=IEA, GO:0005216=IEA, GO:0007601=IEA, GO:0001570=IEA, GO:0016044=TAS} cardiac muscle tissue development, cell communication, cell development, cell-cell junction assembly, cellular membrane organization, gap junction assembly, muscle contraction, regulation of atrial cardiac muscle cell action potential, synaptic transmission, transport, vasculogenesis, visual perception connexon complex, endoplasmic reticulum membrane, gap junction, integral to membrane, intercalated disc, plasma membrane gap junction channel activity, ion channel activity Human GJC2 ENSEMBL UniProtKB {GO:0008219=GO_REF:0000037, GO:0005243=GO_REF:0000019, GO:0043209=GO_REF:0000019, GO:0007267=GO_REF:0000019, GO:0009636=GO_REF:0000019, GO:0005922=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q5T442 Gap junction gamma-2 protein protein 20130413 {GO:0008219=IEA, GO:0005243=IEA, GO:0043209=IEA, GO:0007267=IEA, GO:0009636=IEA, GO:0005922=IEA, GO:0016021=IEA} cell death, cell-cell signaling, response to toxic substance connexon complex, integral to membrane, myelin sheath gap junction channel activity Human Ensembl:ENSMUSP00000104421 GJD2 Reactome UniProtKB {GO:0005243=Reactome:REACT_16981, GO:0007154=GO_REF:0000029, GO:0005886=Reactome:REACT_16989, GO:0007268=Reactome:REACT_13685, GO:0005921=GO_REF:0000029, GO:0005922=GO_REF:0000002, GO:0001508=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007601=GO_REF:0000019} Q9UKL4 Gap junction delta-2 protein protein 20130213 {GO:0005243=TAS, GO:0007154=NAS, GO:0005886=TAS, GO:0007268=TAS, GO:0005921=NAS, GO:0005922=IEA, GO:0001508=IEA, GO:0016021=IEA, GO:0007601=IEA} cell communication, regulation of action potential, synaptic transmission, visual perception connexon complex, gap junction, integral to membrane, plasma membrane gap junction channel activity Human GJD3 IntAct UniProtKB {GO:0005515=PMID:12154091, GO:0007154=PMID:12154091, GO:0009986=PMID:12154091, GO:0005887=PMID:12154091, GO:0005922=PMID:12154091, GO:0016264=PMID:12154091, GO:0016021=GO_REF:0000038, GO:0005216=GO_REF:0000019} Q8N144 Gap junction delta-3 protein protein 20130415 {GO:0005515=IPI, GO:0007154=TAS, GO:0009986=IDA, GO:0005887=TAS, GO:0005922=IDA, GO:0016264=IDA, GO:0016021=IEA, GO:0005216=IEA} cell communication, gap junction assembly cell surface, connexon complex, integral to membrane, integral to plasma membrane ion channel activity, protein binding Human UniProtKB:Q07157 GJD4 UniProtKB UniProtKB {GO:0007154=GO_REF:0000002, GO:0005922=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q96KN9 Gap junction delta-4 protein protein 20130413 {GO:0007154=IEA, GO:0005922=IEA, GO:0016021=IEA} cell communication connexon complex, integral to membrane Human UniProtKB-KW:KW-0812 GK BHF-UCL UniProtKB {GO:0005515=PMID:21988832, GO:0004370=PMID:8651297, GO:0019563=GO_REF:0000041, GO:0005975=GO_REF:0000002, GO:0005741=GO_REF:0000029, GO:0044281=Reactome:REACT_111217, GO:0006072=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0006071=PMID:8499898, GO:0046167=PMID:8651297, GO:0005829=Reactome:REACT_724, GO:0005737=GO_REF:0000029, GO:0019432=Reactome:REACT_1190, GO:0006641=PMID:8651297, GO:0044255=Reactome:REACT_22279} P32189 Glycerol kinase protein 20110817 {GO:0005515=IPI, GO:0004370=IMP, GO:0019563=IEA, GO:0005975=IEA, GO:0005741=NAS, GO:0044281=TAS, GO:0006072=IEA, GO:0005524=IEA, GO:0006071=IMP, GO:0046167=IMP, GO:0005829=TAS, GO:0005737=NAS, GO:0019432=TAS, GO:0006641=IMP, GO:0044255=TAS} carbohydrate metabolic process, cellular lipid metabolic process, glycerol catabolic process, glycerol metabolic process, glycerol-3-phosphate biosynthetic process, glycerol-3-phosphate metabolic process, small molecule metabolic process, triglyceride biosynthetic process, triglyceride metabolic process cytoplasm, cytosol, mitochondrial outer membrane ATP binding, glycerol kinase activity, protein binding Human GK5 UniPathway UniProtKB {GO:0019563=GO_REF:0000041, GO:0004370=GO_REF:0000003, GO:0005975=GO_REF:0000002, GO:0016773=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q6ZS86 Putative glycerol kinase 5 protein 20130413 {GO:0019563=IEA, GO:0004370=IEA, GO:0005975=IEA, GO:0016773=IEA, GO:0005524=IEA} carbohydrate metabolic process, glycerol catabolic process ATP binding, glycerol kinase activity, phosphotransferase activity, alcohol group as acceptor Human UniPathway:UPA00618 GKAP1 UniProtKB UniProtKB {GO:0007165=GO_REF:0000024, GO:0005794=GO_REF:0000024, GO:0016301=GO_REF:0000038} Q5VSY0 G kinase-anchoring protein 1 protein 20040430 {GO:0007165=ISS, GO:0005794=ISS, GO:0016301=IEA} signal transduction Golgi apparatus kinase activity Human UniProtKB:Q9JMB0 GKN1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008284=GO_REF:0000019, GO:0007586=PMID:10835488, GO:0005576=GO_REF:0000039, GO:0051781=GO_REF:0000037, GO:0005575=GO_REF:0000015, GO:0030141=GO_REF:0000019, GO:0008083=GO_REF:0000019} Q9NS71 Gastrokine-1 protein 20061026 {GO:0003674=ND, GO:0008284=IEA, GO:0007586=NAS, GO:0005576=IEA, GO:0051781=IEA, GO:0005575=ND, GO:0030141=IEA, GO:0008083=IEA} digestion, positive regulation of cell division, positive regulation of cell proliferation cellular_component, extracellular region, secretory granule growth factor activity, molecular_function Human GKN2 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q86XP6 Gastrokine-2 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 GLA Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0005515=PMID:1332979, GO:0009311=PMID:39940, GO:0005794=PMID:1332979, GO:0006687=Reactome:REACT_116105, GO:0046477=GO_REF:0000024, GO:0052692=GO_REF:0000003, GO:0046479=PMID:2160973, GO:0005102=PMID:1332979, GO:0016936=GO_REF:0000019, GO:0016139=GO_REF:0000033, GO:0005576=PMID:1332979, GO:0044281=Reactome:REACT_111217, GO:0003824=PMID:39940, GO:0005764=PMID:1332979, GO:0042803=PMID:6256390, GO:0005737=PMID:1332979, GO:0051001=GO_REF:0000024, GO:0016787=PMID:7911050, GO:0045019=GO_REF:0000024, GO:0004557=Reactome:REACT_115752, GO:0043202=Reactome:REACT_115752} P06280 Alpha-galactosidase A protein 20110921 {GO:0006665=TAS, GO:0005515=IPI, GO:0009311=IDA, GO:0005794=IMP, GO:0006687=TAS, GO:0046477=ISS, GO:0052692=IEA, GO:0046479=TAS, GO:0005102=IDA, GO:0016936=IEA, GO:0016139=IBA, GO:0005576=IMP, GO:0044281=TAS, GO:0003824=IDA, GO:0005764=IMP, GO:0042803=IDA, GO:0005737=IMP, GO:0051001=ISS, GO:0016787=TAS, GO:0045019=ISS, GO:0004557=TAS, GO:0043202=TAS} glycoside catabolic process, glycosphingolipid catabolic process, glycosphingolipid metabolic process, glycosylceramide catabolic process, negative regulation of nitric oxide biosynthetic process, negative regulation of nitric-oxide synthase activity, oligosaccharide metabolic process, small molecule metabolic process, sphingolipid metabolic process Golgi apparatus, cytoplasm, extracellular region, lysosomal lumen, lysosome alpha-galactosidase activity, catalytic activity, galactoside binding, hydrolase activity, protein binding, protein homodimerization activity, raffinose alpha-galactosidase activity, receptor binding Human GLB1 Reactome UniProtKB {GO:0005515=PMID:15498789, GO:0006665=Reactome:REACT_19323, GO:0004565=PMID:3143362, GO:0048471=GO_REF:0000039, GO:0006687=Reactome:REACT_116105, GO:0005975=Reactome:REACT_474, GO:0019388=GO_REF:0000019, GO:0016936=GO_REF:0000019, GO:0006027=Reactome:REACT_120752, GO:0044281=Reactome:REACT_111217, GO:0005764=GO_REF:0000019, GO:0004553=GO_REF:0000002, GO:0042339=Reactome:REACT_121288, GO:0042340=Reactome:REACT_121313, GO:0030203=Reactome:REACT_121315, GO:0043202=Reactome:REACT_121086} P16278 Beta-galactosidase protein 20110921 {GO:0005515=IPI, GO:0006665=TAS, GO:0004565=TAS, GO:0048471=IEA, GO:0006687=TAS, GO:0005975=TAS, GO:0019388=IEA, GO:0016936=IEA, GO:0006027=TAS, GO:0044281=TAS, GO:0005764=IEA, GO:0004553=IEA, GO:0042339=TAS, GO:0042340=TAS, GO:0030203=TAS, GO:0043202=TAS} carbohydrate metabolic process, galactose catabolic process, glycosaminoglycan catabolic process, glycosaminoglycan metabolic process, glycosphingolipid metabolic process, keratan sulfate catabolic process, keratan sulfate metabolic process, small molecule metabolic process, sphingolipid metabolic process lysosomal lumen, lysosome, perinuclear region of cytoplasm beta-galactosidase activity, galactoside binding, hydrolase activity, hydrolyzing O-glycosyl compounds, protein binding Human GLB1L UniProtKB UniProtKB {GO:0004565=GO_REF:0000002, GO:0005975=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0004553=GO_REF:0000002} Q6UWU2 Beta-galactosidase-1-like protein protein 20130413 {GO:0004565=IEA, GO:0005975=IEA, GO:0005576=IEA, GO:0004553=IEA} carbohydrate metabolic process extracellular region beta-galactosidase activity, hydrolase activity, hydrolyzing O-glycosyl compounds Human UniProtKB-SubCell:SL-0243 GLB1L2 UniProtKB UniProtKB {GO:0004565=GO_REF:0000002, GO:0005975=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0004553=GO_REF:0000002} Q8IW92 Beta-galactosidase-1-like protein 2 protein 20130413 {GO:0004565=IEA, GO:0005975=IEA, GO:0005576=IEA, GO:0004553=IEA} carbohydrate metabolic process extracellular region beta-galactosidase activity, hydrolase activity, hydrolyzing O-glycosyl compounds Human UniProtKB-SubCell:SL-0243 GLCCI1 ENSEMBL UniProtKB {GO:0005737=GO_REF:0000019} Q86VQ1 Glucocorticoid-induced transcript 1 protein protein 20130413 {GO:0005737=IEA} cytoplasm Human Ensembl:ENSMUSP00000069444 GLCE Reactome UniProtKB {GO:0005794=GO_REF:0000024, GO:0000139=GO_REF:0000039, GO:0005975=Reactome:REACT_474, GO:0050379=PMID:15853773, GO:0016857=GO_REF:0000024, GO:0047464=PMID:20118238, GO:0044281=Reactome:REACT_111217, GO:0015012=PMID:20118238, GO:0016021=GO_REF:0000037, GO:0030203=Reactome:REACT_121315, GO:0006024=Reactome:REACT_121248, GO:0030210=GO_REF:0000024} O94923 D-glucuronyl C5-epimerase protein 20130301 {GO:0005794=ISS, GO:0000139=IEA, GO:0005975=TAS, GO:0050379=IDA, GO:0016857=ISS, GO:0047464=IMP, GO:0044281=TAS, GO:0015012=IDA, GO:0016021=IEA, GO:0030203=TAS, GO:0006024=TAS, GO:0030210=ISS} carbohydrate metabolic process, glycosaminoglycan biosynthetic process, glycosaminoglycan metabolic process, heparan sulfate proteoglycan biosynthetic process, heparin biosynthetic process, small molecule metabolic process Golgi apparatus, Golgi membrane, integral to membrane UDP-glucuronate 5'-epimerase activity, heparosan-N-sulfate-glucuronate 5-epimerase activity, racemase and epimerase activity, acting on carbohydrates and derivatives Human GLDC UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0030170=GO_REF:0000002, GO:0009055=PMID:2268343, GO:0006546=GO_REF:0000002, GO:0004375=GO_REF:0000003, GO:0016829=GO_REF:0000002} P23378 "Glycine dehydrogenase ""decarboxylating"", mitochondrial" protein 20060428 {GO:0005739=IEA, GO:0030170=IEA, GO:0009055=TAS, GO:0006546=IEA, GO:0004375=IEA, GO:0016829=IEA} glycine catabolic process mitochondrion electron carrier activity, glycine dehydrogenase (decarboxylating) activity, lyase activity, pyridoxal phosphate binding Human GLE1 PINC UniProtKB {GO:0005737=GO_REF:0000039, GO:0006406=PMID:9618489, GO:0016973=GO_REF:0000002, GO:0005643=GO_REF:0000039, GO:0015031=GO_REF:0000037} Q53GS7 Nucleoporin GLE1 protein 20061106 {GO:0005737=IEA, GO:0006406=TAS, GO:0016973=IEA, GO:0005643=IEA, GO:0015031=IEA} mRNA export from nucleus, poly(A)+ mRNA export from nucleus, protein transport cytoplasm, nuclear pore Human GLG1 PINC UniProtKB {GO:0031012=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0000139=GO_REF:0000039, GO:0060349=GO_REF:0000019, GO:0005102=PMID:7531823, GO:0032330=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0010955=GO_REF:0000019, GO:0030512=GO_REF:0000019} Q92896 Golgi apparatus protein 1 protein 20030904 {GO:0031012=IEA, GO:0016020=IEA, GO:0000139=IEA, GO:0060349=IEA, GO:0005102=TAS, GO:0032330=IEA, GO:0016021=IEA, GO:0010955=IEA, GO:0030512=IEA} bone morphogenesis, negative regulation of protein processing, negative regulation of transforming growth factor beta receptor signaling pathway, regulation of chondrocyte differentiation Golgi membrane, extracellular matrix, integral to membrane, membrane receptor binding Human GLI1 BHF-UCL UniProtKB {GO:0005515=PMID:22439934, GO:0008017=GO_REF:0000019, GO:0008284=PMID:12165851, GO:0044212=PMID:17035233, GO:0030324=GO_REF:0000019, GO:0021696=GO_REF:0000019, GO:0003705=GO_REF:0000019, GO:0021983=GO_REF:0000019, GO:0009954=GO_REF:0000019, GO:0005634=PMID:19878745, GO:0009953=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0007224=PMID:11001584, GO:0005829=PMID:18559511, GO:0045880=PMID:17035233, GO:0005737=PMID:16229683, GO:0045944=PMID:9118802, GO:0090090=PMID:17035233, GO:0060032=GO_REF:0000019, GO:0021938=GO_REF:0000019, GO:0045740=PMID:12165851, GO:0048546=PMID:11001584, GO:0003677=PMID:9118802, GO:0001649=PMID:12165851, GO:0007418=GO_REF:0000019, GO:0009913=PMID:12165851, GO:0005929=GO_REF:0000019, GO:0008589=PMID:11238441, GO:0003682=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0045893=PMID:11238441} P08151 Zinc finger protein GLI1 protein 20111120 {GO:0005515=IPI, GO:0008017=IEA, GO:0008284=IMP, GO:0044212=IDA, GO:0030324=IEA, GO:0021696=IEA, GO:0003705=IEA, GO:0021983=IEA, GO:0009954=IEA, GO:0005634=IDA, GO:0009953=IEA, GO:0007283=IEA, GO:0007224=TAS, GO:0005829=IDA, GO:0045880=IDA, GO:0005737=IDA, GO:0045944=IDA, GO:0090090=IMP, GO:0060032=IEA, GO:0021938=IEA, GO:0045740=IDA, GO:0048546=TAS, GO:0003677=IDA, GO:0001649=IDA, GO:0007418=IEA, GO:0009913=IDA, GO:0005929=IEA, GO:0008589=TAS, GO:0003682=IEA, GO:0008270=IEA, GO:0045893=IDA} cerebellar cortex morphogenesis, digestive tract morphogenesis, dorsal/ventral pattern formation, epidermal cell differentiation, lung development, negative regulation of canonical Wnt receptor signaling pathway, notochord regression, osteoblast differentiation, pituitary gland development, positive regulation of DNA replication, positive regulation of cell proliferation, positive regulation of smoothened signaling pathway, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, proximal/distal pattern formation, regulation of smoothened signaling pathway, smoothened signaling pathway, smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation, spermatogenesis, ventral midline development cilium, cytoplasm, cytosol, nucleus DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, chromatin binding, microtubule binding, protein binding, transcription regulatory region DNA binding, zinc ion binding Human GLI2 ENSEMBL UniProtKB {GO:0005515=PMID:12435627, GO:0033089=GO_REF:0000024, GO:0007389=GO_REF:0000024, GO:0003700=GO_REF:0000019, GO:0044212=GO_REF:0000019, GO:0021696=GO_REF:0000019, GO:0021965=GO_REF:0000019, GO:0030879=GO_REF:0000024, GO:0007224=PMID:15994174, GO:0007507=GO_REF:0000019, GO:0048589=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0060603=GO_REF:0000019, GO:0060032=GO_REF:0000019, GO:0021938=GO_REF:0000019, GO:0045740=PMID:12165851, GO:0000122=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0007418=GO_REF:0000024, GO:0001501=GO_REF:0000019, GO:0002076=GO_REF:0000019, GO:0008270=PMID:8378770, GO:0045893=PMID:15175043, GO:0042733=GO_REF:0000019, GO:0021513=GO_REF:0000024, GO:0030324=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:0021983=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0009954=GO_REF:0000019, GO:0060831=GO_REF:0000019, GO:0021517=GO_REF:0000024, GO:0021776=GO_REF:0000019, GO:0021775=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0048666=GO_REF:0000024, GO:0045944=GO_REF:0000019, GO:0090103=GO_REF:0000019, GO:0042475=GO_REF:0000019, GO:0032331=GO_REF:0000019, GO:0001822=GO_REF:0000019, GO:0006915=GO_REF:0000019, GO:0021508=GO_REF:0000019, GO:0031512=GO_REF:0000019, GO:0048566=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0009612=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0071407=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0045666=GO_REF:0000019, GO:0008589=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0007442=GO_REF:0000019, GO:0060513=GO_REF:0000019, GO:0060322=GO_REF:0000019, GO:0035295=GO_REF:0000024, GO:0048754=GO_REF:0000019, GO:0030902=GO_REF:0000024} Q1PSW9 Zinc finger protein GLI2 protein 20130413 {GO:0005515=IPI, GO:0033089=ISS, GO:0007389=ISS, GO:0003700=IEA, GO:0044212=IEA, GO:0021696=IEA, GO:0021965=IEA, GO:0030879=ISS, GO:0007224=IDA, GO:0007507=IEA, GO:0048589=IEA, GO:0007411=IEA, GO:0060603=IEA, GO:0060032=IEA, GO:0021938=IEA, GO:0045740=IDA, GO:0000122=IEA, GO:0001701=IEA, GO:0007418=ISS, GO:0001501=IEA, GO:0002076=IEA, GO:0008270=IDA, GO:0045893=IDA, GO:0042733=IEA, GO:0021513=ISS, GO:0030324=IEA, GO:0008283=IEA, GO:0021983=IEA, GO:0005634=IEA, GO:0009954=IEA, GO:0060831=IEA, GO:0021517=ISS, GO:0021776=IEA, GO:0021775=IEA, GO:0005737=IEA, GO:0048666=ISS, GO:0045944=IEA, GO:0090103=IEA, GO:0042475=IEA, GO:0032331=IEA, GO:0001822=IEA, GO:0006915=IEA, GO:0021508=IEA, GO:0031512=IEA, GO:0048566=IEA, GO:0006351=IEA, GO:0009612=IEA, GO:0043565=IEA, GO:0071407=IEA, GO:0016020=IEA, GO:0045666=IEA, GO:0008589=IEA, GO:0003682=IEA, GO:0007442=IEA, GO:0060513=IEA, GO:0060322=IEA, GO:0035295=ISS, GO:0048754=IEA, GO:0030902=ISS} apoptotic process, axon guidance, branching morphogenesis of an epithelial tube, cell proliferation, cellular response to organic cyclic compound, cerebellar cortex morphogenesis, cochlea morphogenesis, developmental growth, embryonic digestive tract development, embryonic digit morphogenesis, floor plate formation, head development, heart development, hindbrain development, hindgut morphogenesis, in utero embryonic development, kidney development, lung development, mammary gland development, mammary gland duct morphogenesis, negative regulation of chondrocyte differentiation, negative regulation of transcription from RNA polymerase II promoter, neuron development, notochord regression, odontogenesis of dentin-containing tooth, osteoblast development, pattern specification process, pituitary gland development, positive regulation of DNA replication, positive regulation of T cell differentiation in thymus, positive regulation of neuron differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, prostatic bud formation, proximal/distal pattern formation, regulation of smoothened signaling pathway, response to mechanical stimulus, skeletal system development, smoothened signaling pathway, smoothened signaling pathway involved in dorsal/ventral neural tube patterning, smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation, smoothened signaling pathway involved in spinal cord motor neuron cell fate specification, smoothened signaling pathway involved in ventral spinal cord interneuron specification, spinal cord dorsal/ventral patterning, spinal cord ventral commissure morphogenesis, transcription, DNA-dependent, tube development, ventral midline development, ventral spinal cord development cytoplasm, membrane, motile primary cilium, nucleus chromatin binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding, zinc ion binding Human Ensembl:ENSMUSP00000054837 GLI3 HPA UniProtKB {GO:0005515=PMID:16371461, GO:0001656=GO_REF:0000019, GO:0046638=GO_REF:0000024, GO:0001658=GO_REF:0000019, GO:0003700=PMID:10077605, GO:0008013=PMID:17331723, GO:0048709=GO_REF:0000019, GO:0048704=GO_REF:0000019, GO:0048593=GO_REF:0000019, GO:0021861=GO_REF:0000019, GO:0043231=GO_REF:0000052, GO:0007224=PMID:11001584, GO:0046639=GO_REF:0000024, GO:0061005=GO_REF:0000019, GO:0007507=GO_REF:0000019, GO:0048589=GO_REF:0000019, GO:0021798=GO_REF:0000019, GO:0016485=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0017053=GO_REF:0000019, GO:0035035=PMID:10075717, GO:0033077=GO_REF:0000024, GO:0070242=GO_REF:0000024, GO:0000122=PMID:19084012, GO:0001701=GO_REF:0000019, GO:0005929=PMID:16254602, GO:0022018=GO_REF:0000019, GO:0016592=PMID:17000779, GO:0042307=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0045893=GO_REF:0000024, GO:0043586=GO_REF:0000019, GO:0021631=GO_REF:0000019, GO:0045892=PMID:19084012, GO:0042733=PMID:11001584, GO:0043585=PMID:11001584, GO:0060873=GO_REF:0000019, GO:0060594=GO_REF:0000019, GO:0060875=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0042826=PMID:12435627, GO:0030324=GO_REF:0000019, GO:0021801=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0009954=GO_REF:0000019, GO:0045879=GO_REF:0000024, GO:0060831=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0005829=PMID:18559511, GO:0021776=GO_REF:0000019, GO:0021775=GO_REF:0000019, GO:0005737=PMID:10077605, GO:0045944=PMID:17000779, GO:0042475=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:0032332=GO_REF:0000019, GO:0035108=PMID:9354785, GO:0090090=PMID:17331723, GO:0043066=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0002052=GO_REF:0000019, GO:0030318=GO_REF:0000019, GO:0048566=PMID:11001584, GO:0060840=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0045669=GO_REF:0000019, GO:0060366=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0060364=GO_REF:0000019, GO:0045665=GO_REF:0000019, GO:0048557=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0007442=GO_REF:0000019, GO:0045060=GO_REF:0000024, GO:0060367=GO_REF:0000019} P10071 Transcriptional activator GLI3 protein 20080818 {GO:0005515=IPI, GO:0001656=IEA, GO:0046638=ISS, GO:0001658=IEA, GO:0003700=IDA, GO:0008013=IPI, GO:0048709=IEA, GO:0048704=IEA, GO:0048593=IEA, GO:0021861=IEA, GO:0043231=IDA, GO:0007224=TAS, GO:0046639=ISS, GO:0061005=IEA, GO:0007507=IEA, GO:0048589=IEA, GO:0021798=IEA, GO:0016485=IEA, GO:0007411=IEA, GO:0017053=IEA, GO:0035035=IPI, GO:0033077=ISS, GO:0070242=ISS, GO:0000122=IDA, GO:0001701=IEA, GO:0005929=IDA, GO:0022018=IEA, GO:0016592=IDA, GO:0042307=IEA, GO:0008270=IEA, GO:0045893=ISS, GO:0043586=IEA, GO:0021631=IEA, GO:0045892=IDA, GO:0042733=TAS, GO:0043585=TAS, GO:0060873=IEA, GO:0060594=IEA, GO:0060875=IEA, GO:0008285=IEA, GO:0042826=IDA, GO:0030324=IEA, GO:0021801=IEA, GO:0005634=IDA, GO:0009954=IEA, GO:0045879=ISS, GO:0060831=IEA, GO:0009952=IEA, GO:0005829=IDA, GO:0021776=IEA, GO:0021775=IEA, GO:0005737=IDA, GO:0045944=IDA, GO:0042475=IEA, GO:0060021=IEA, GO:0032332=IEA, GO:0035108=IMP, GO:0090090=IDA, GO:0043066=IEA, GO:0005730=IDA, GO:0002052=IEA, GO:0030318=IEA, GO:0048566=TAS, GO:0060840=IEA, GO:0006351=IEA, GO:0045669=IEA, GO:0060366=IEA, GO:0043565=IEA, GO:0060364=IEA, GO:0045665=IEA, GO:0048557=IEA, GO:0003682=IEA, GO:0007442=IEA, GO:0045060=ISS, GO:0060367=IEA} T cell differentiation in thymus, anterior semicircular canal development, anterior/posterior pattern specification, artery development, axon guidance, branching involved in ureteric bud morphogenesis, camera-type eye morphogenesis, cell differentiation involved in kidney development, cerebral cortex radial glia guided migration, developmental growth, embryonic digestive tract development, embryonic digestive tract morphogenesis, embryonic digit morphogenesis, embryonic skeletal system morphogenesis, forebrain dorsal/ventral pattern formation, forebrain radial glial cell differentiation, frontal suture morphogenesis, heart development, hindgut morphogenesis, in utero embryonic development, lambdoid suture morphogenesis, lateral ganglionic eminence cell proliferation, lateral semicircular canal development, limb morphogenesis, lung development, mammary gland specification, melanocyte differentiation, metanephros development, negative regulation of alpha-beta T cell differentiation, negative regulation of apoptotic process, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cell proliferation, negative regulation of neuron differentiation, negative regulation of smoothened signaling pathway, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, negative thymic T cell selection, nose morphogenesis, odontogenesis of dentin-containing tooth, oligodendrocyte differentiation, optic nerve morphogenesis, palate development, positive regulation of alpha-beta T cell differentiation, positive regulation of chondrocyte differentiation, positive regulation of neuroblast proliferation, positive regulation of osteoblast differentiation, positive regulation of protein import into nucleus, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein processing, proximal/distal pattern formation, sagittal suture morphogenesis, smoothened signaling pathway, smoothened signaling pathway involved in dorsal/ventral neural tube patterning, smoothened signaling pathway involved in spinal cord motor neuron cell fate specification, smoothened signaling pathway involved in ventral spinal cord interneuron specification, thymocyte apoptotic process, tongue development, transcription, DNA-dependent cilium, cytoplasm, cytosol, intracellular membrane-bounded organelle, mediator complex, nucleolus, nucleus, transcriptional repressor complex beta-catenin binding, chromatin binding, histone acetyltransferase binding, histone deacetylase binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human GLIPR1L2 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q4G1C9 GLIPR1-like protein 2 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 GLIPR2 UniProtKB UniProtKB {GO:0000139=GO_REF:0000039, GO:0005576=GO_REF:0000002} Q9H4G4 Golgi-associated plant pathogenesis-related protein 1 protein 20130413 {GO:0000139=IEA, GO:0005576=IEA} Golgi membrane, extracellular region Human UniProtKB-SubCell:SL-0134 GLIS2 BHF-UCL UniProtKB {GO:0044212=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0045879=GO_REF:0000024, GO:0000122=GO_REF:0000024, GO:0030154=GO_REF:0000037, GO:0043433=GO_REF:0000024, GO:0007399=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0001077=GO_REF:0000024, GO:0016607=GO_REF:0000024, GO:0045944=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0045893=GO_REF:0000024, GO:0045892=GO_REF:0000024} Q9BZE0 Zinc finger protein GLIS2 protein 20101220 {GO:0044212=ISS, GO:0005634=ISS, GO:0045879=ISS, GO:0000122=ISS, GO:0030154=IEA, GO:0043433=ISS, GO:0007399=IEA, GO:0005737=IEA, GO:0001077=ISS, GO:0016607=ISS, GO:0045944=ISS, GO:0008270=IEA, GO:0045893=ISS, GO:0045892=ISS} cell differentiation, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of smoothened signaling pathway, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, nervous system development, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent cytoplasm, nuclear speck, nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, transcription regulatory region DNA binding, zinc ion binding Human UniProtKB:Q8VDL9 GLMN GOC UniProtKB {GO:0005515=PMID:11164950, GO:0031461=PMID:22405651, GO:0032434=PMID:22405651, GO:0050715=PMID:12604780, GO:0042130=PMID:12604780, GO:0005622=PMID:12604780, GO:0042692=PMID:11845407, GO:0045086=PMID:12604780, GO:0031463=PMID:22405651, GO:0040029=PMID:12604780, GO:0031462=PMID:22405651, GO:0055105=PMID:22405651, GO:0031464=PMID:22405651, GO:0031397=PMID:22405651, GO:0005171=PMID:11571281, GO:0001570=PMID:11845407, GO:0031625=PMID:22405651, GO:0042327=PMID:11571281} Q92990 Glomulin protein 20130413 {GO:0005515=IPI, GO:0031461=IPI, GO:0032434=IMP, GO:0050715=IMP, GO:0042130=IDA, GO:0005622=NAS, GO:0042692=IMP, GO:0045086=IMP, GO:0031463=IPI, GO:0040029=IMP, GO:0031462=IPI, GO:0055105=IGI, GO:0031464=IPI, GO:0031397=IGI, GO:0005171=IPI, GO:0001570=IMP, GO:0031625=IDA, GO:0042327=IDA} muscle cell differentiation, negative regulation of T cell proliferation, negative regulation of protein ubiquitination, positive regulation of cytokine secretion, positive regulation of interleukin-2 biosynthetic process, positive regulation of phosphorylation, regulation of gene expression, epigenetic, regulation of proteasomal ubiquitin-dependent protein catabolic process, vasculogenesis Cul2-RING ubiquitin ligase complex, Cul3-RING ubiquitin ligase complex, Cul4A-RING ubiquitin ligase complex, cullin-RING ubiquitin ligase complex, intracellular hepatocyte growth factor receptor binding, protein binding, ubiquitin protein ligase binding, ubiquitin-protein ligase inhibitor activity Human UniProtKB:P62877 GLO1 UniProtKB UniProtKB {GO:0005737=PMID:16130169, GO:0043066=PMID:11489834, GO:0006357=GO_REF:0000019, GO:0005975=GO_REF:0000019, GO:0006749=GO_REF:0000019, GO:0004462=PMID:11489834, GO:0009438=GO_REF:0000019, GO:0046872=GO_REF:0000037} Q04760 Lactoylglutathione lyase protein 20060130 {GO:0005737=TAS, GO:0043066=IDA, GO:0006357=IEA, GO:0005975=IEA, GO:0006749=IEA, GO:0004462=IDA, GO:0009438=IEA, GO:0046872=IEA} carbohydrate metabolic process, glutathione metabolic process, methylglyoxal metabolic process, negative regulation of apoptotic process, regulation of transcription from RNA polymerase II promoter cytoplasm lactoylglutathione lyase activity, metal ion binding Human GLOD4 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039} Q9HC38 Glyoxalase domain-containing protein 4 protein 20130413 {GO:0005739=IEA} mitochondrion Human UniProtKB-SubCell:SL-0173 GLP1R Reactome UniProtKB {GO:0007190=PMID:8405712, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0005886=Reactome:REACT_22268, GO:0019933=PMID:7589461, GO:0008528=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0007204=PMID:7589461, GO:0004967=GO_REF:0000002, GO:0004888=PMID:8405712} P43220 Glucagon-like peptide 1 receptor protein 20130213 {GO:0007190=TAS, GO:0006112=TAS, GO:0050796=TAS, GO:0005886=TAS, GO:0019933=IDA, GO:0008528=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0007204=IDA, GO:0004967=IEA, GO:0004888=TAS} activation of adenylate cyclase activity, cAMP-mediated signaling, elevation of cytosolic calcium ion concentration, energy reserve metabolic process, regulation of insulin secretion, small molecule metabolic process integral to membrane, plasma membrane G-protein coupled peptide receptor activity, glucagon receptor activity, transmembrane signaling receptor activity Human GLP2R Reactome UniProtKB {GO:0008284=PMID:9990065, GO:0005886=Reactome:REACT_22268, GO:0004930=PMID:9990065, GO:0007188=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0004967=GO_REF:0000019} O95838 Glucagon-like peptide 2 receptor protein 20130213 {GO:0008284=TAS, GO:0005886=TAS, GO:0004930=TAS, GO:0007188=IEA, GO:0016021=IEA, GO:0004967=IEA} adenylate cyclase-modulating G-protein coupled receptor signaling pathway, positive regulation of cell proliferation integral to membrane, plasma membrane G-protein coupled receptor activity, glucagon receptor activity Human GLRA1 UniProtKB UniProtKB {GO:0005515=PMID:11929858, GO:0006821=PMID:8137830, GO:0005230=GO_REF:0000002, GO:0030054=GO_REF:0000038, GO:0022824=GO_REF:0000002, GO:0005886=Reactome:REACT_25304, GO:0005783=GO_REF:0000019, GO:0051970=PMID:11973623, GO:0051291=GO_REF:0000019, GO:0043231=PMID:7506679, GO:0016934=PMID:7920629, GO:0001964=PMID:8298642, GO:0002087=GO_REF:0000019, GO:0034220=Reactome:REACT_25387, GO:0006936=PMID:11973623, GO:0007218=PMID:2155780, GO:0045211=GO_REF:0000038, GO:0042391=PMID:7920629, GO:0050884=GO_REF:0000019, GO:0007628=GO_REF:0000019, GO:0051260=GO_REF:0000019, GO:0006811=PMID:2155780, GO:0034707=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:2000344=PMID:11751269, GO:0030977=PMID:15748848, GO:0060080=GO_REF:0000019, GO:0005887=GO_REF:0000002, GO:0016594=GO_REF:0000002, GO:0016021=PMID:15952785, GO:0007340=GO_REF:0000019, GO:0001508=GO_REF:0000019, GO:0007601=GO_REF:0000019, GO:0060012=GO_REF:0000019, GO:0009897=GO_REF:0000019, GO:0060013=GO_REF:0000019} Q14C71 GLRA1 protein protein 20130413 {GO:0005515=IPI, GO:0006821=IDA, GO:0005230=IEA, GO:0030054=IEA, GO:0022824=IEA, GO:0005886=TAS, GO:0005783=IEA, GO:0051970=IMP, GO:0051291=IEA, GO:0043231=IDA, GO:0016934=IMP, GO:0001964=IMP, GO:0002087=IEA, GO:0034220=TAS, GO:0006936=IMP, GO:0007218=IDA, GO:0045211=IEA, GO:0042391=IMP, GO:0050884=IEA, GO:0007628=IEA, GO:0051260=IEA, GO:0006811=IDA, GO:0034707=IEA, GO:0055085=TAS, GO:2000344=IMP, GO:0030977=IDA, GO:0060080=IEA, GO:0005887=IEA, GO:0016594=IEA, GO:0016021=NAS, GO:0007340=IEA, GO:0001508=IEA, GO:0007601=IEA, GO:0060012=IEA, GO:0009897=IEA, GO:0060013=IEA} acrosome reaction, adult walking behavior, chloride transport, ion transmembrane transport, ion transport, muscle contraction, negative regulation of transmission of nerve impulse, neuromuscular process controlling posture, neuropeptide signaling pathway, positive regulation of acrosome reaction, protein heterooligomerization, protein homooligomerization, regulation of action potential, regulation of inhibitory postsynaptic membrane potential, regulation of membrane potential, regulation of respiratory gaseous exchange by neurological system process, righting reflex, startle response, synaptic transmission, glycinergic, transmembrane transport, visual perception cell junction, chloride channel complex, endoplasmic reticulum, external side of plasma membrane, integral to membrane, integral to plasma membrane, intracellular membrane-bounded organelle, plasma membrane, postsynaptic membrane extracellular ligand-gated ion channel activity, extracellular-glycine-gated chloride channel activity, glycine binding, protein binding, taurine binding, transmitter-gated ion channel activity Human UniProtKB-KW:KW-0628 GLRA2 Reactome UniProtKB {GO:0005230=GO_REF:0000002, GO:0022824=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25304, GO:0034707=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0007416=GO_REF:0000019, GO:0016934=PMID:2155780, GO:0034220=Reactome:REACT_25387, GO:0005887=PMID:2155780, GO:0007218=PMID:2155780, GO:0045211=GO_REF:0000039, GO:0016594=PMID:2155780, GO:0006811=PMID:2155780} P23416 Glycine receptor subunit alpha-2 protein 20130301 {GO:0005230=IEA, GO:0022824=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0034707=IEA, GO:0055085=TAS, GO:0007416=IEA, GO:0016934=IDA, GO:0034220=TAS, GO:0005887=NAS, GO:0007218=IDA, GO:0045211=IEA, GO:0016594=IDA, GO:0006811=IDA} ion transmembrane transport, ion transport, neuropeptide signaling pathway, synapse assembly, transmembrane transport cell junction, chloride channel complex, integral to plasma membrane, plasma membrane, postsynaptic membrane extracellular ligand-gated ion channel activity, extracellular-glycine-gated chloride channel activity, glycine binding, transmitter-gated ion channel activity Human GLRB Reactome UniProtKB {GO:0005515=PMID:15215304, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25304, GO:0034707=GO_REF:0000037, GO:0007268=PMID:11929858, GO:0055085=Reactome:REACT_15518, GO:0051291=GO_REF:0000019, GO:0016933=PMID:11929858, GO:0007399=PMID:11929858, GO:0016934=Reactome:REACT_25304, GO:0001964=PMID:11929858, GO:0034220=Reactome:REACT_25387, GO:0007218=PMID:8717357, GO:0005887=PMID:8717357, GO:0045211=GO_REF:0000039, GO:0042391=GO_REF:0000019, GO:0016594=PMID:15748848, GO:0007628=GO_REF:0000019, GO:0007340=GO_REF:0000019, GO:0007601=GO_REF:0000019, GO:0060012=GO_REF:0000019, GO:0060013=GO_REF:0000019, GO:0006811=PMID:8717357} P48167 Glycine receptor subunit beta protein 20121220 {GO:0005515=IPI, GO:0030054=IEA, GO:0005886=TAS, GO:0034707=IEA, GO:0007268=IMP, GO:0055085=TAS, GO:0051291=IEA, GO:0016933=IMP, GO:0007399=IMP, GO:0016934=TAS, GO:0001964=IMP, GO:0034220=TAS, GO:0007218=IDA, GO:0005887=NAS, GO:0045211=IEA, GO:0042391=IEA, GO:0016594=IMP, GO:0007628=IEA, GO:0007340=IEA, GO:0007601=IEA, GO:0060012=IEA, GO:0060013=IEA, GO:0006811=IDA} acrosome reaction, adult walking behavior, ion transmembrane transport, ion transport, nervous system development, neuropeptide signaling pathway, protein heterooligomerization, regulation of membrane potential, righting reflex, startle response, synaptic transmission, synaptic transmission, glycinergic, transmembrane transport, visual perception cell junction, chloride channel complex, integral to plasma membrane, plasma membrane, postsynaptic membrane extracellular-glycine-gated chloride channel activity, extracellular-glycine-gated ion channel activity, glycine binding, protein binding Human GLRX Reactome UniProtKB {GO:0005739=GO_REF:0000019, GO:0015949=Reactome:REACT_21330, GO:0047485=PMID:16884690, GO:0015035=GO_REF:0000002, GO:0009055=GO_REF:0000002, GO:0055086=Reactome:REACT_1698, GO:0005634=GO_REF:0000019, GO:0045454=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0015038=PMID:7851394, GO:0022900=GO_REF:0000037, GO:0005829=Reactome:REACT_1461} P35754 Glutaredoxin-1 protein 20130301 {GO:0005739=IEA, GO:0015949=TAS, GO:0047485=IPI, GO:0015035=IEA, GO:0009055=IEA, GO:0055086=TAS, GO:0005634=IEA, GO:0045454=IEA, GO:0044281=TAS, GO:0015038=TAS, GO:0022900=IEA, GO:0005829=TAS} cell redox homeostasis, electron transport chain, nucleobase-containing small molecule interconversion, nucleobase-containing small molecule metabolic process, small molecule metabolic process cytosol, mitochondrion, nucleus electron carrier activity, glutathione disulfide oxidoreductase activity, protein N-terminus binding, protein disulfide oxidoreductase activity Human GLRX2 GOC UniProtKB {GO:0042542=PMID:11397793, GO:0006355=PMID:11297543, GO:0010033=PMID:11397793, GO:0008794=PMID:11297543, GO:0051537=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0015035=GO_REF:0000002, GO:0006915=PMID:11297543, GO:0009055=PMID:11297543, GO:0003756=PMID:11297543, GO:0006749=PMID:11397793, GO:0005634=GO_REF:0000052, GO:0009966=PMID:11297543, GO:0015038=PMID:11397793, GO:0030154=PMID:11297543, GO:0046872=GO_REF:0000037, GO:0009266=PMID:11397793, GO:0005739=PMID:11297543, GO:0006457=PMID:11397793, GO:0042262=PMID:11397793, GO:0051775=PMID:11297543, GO:0045454=PMID:11397793, GO:0022900=GO_REF:0000037} Q9NS18 Glutaredoxin-2, mitochondrial protein 20130413 {GO:0042542=IDA, GO:0006355=NAS, GO:0010033=IDA, GO:0008794=TAS, GO:0051537=IEA, GO:0005730=IDA, GO:0015035=IEA, GO:0006915=NAS, GO:0009055=NAS, GO:0003756=TAS, GO:0006749=TAS, GO:0005634=IDA, GO:0009966=NAS, GO:0015038=TAS, GO:0030154=NAS, GO:0046872=IEA, GO:0009266=NAS, GO:0005739=IDA, GO:0006457=TAS, GO:0042262=NAS, GO:0051775=TAS, GO:0045454=TAS, GO:0022900=IEA} DNA protection, apoptotic process, cell differentiation, cell redox homeostasis, electron transport chain, glutathione metabolic process, protein folding, regulation of signal transduction, regulation of transcription, DNA-dependent, response to hydrogen peroxide, response to organic substance, response to redox state, response to temperature stimulus mitochondrion, nucleolus, nucleus 2 iron, 2 sulfur cluster binding, arsenate reductase (glutaredoxin) activity, electron carrier activity, glutathione disulfide oxidoreductase activity, metal ion binding, protein disulfide isomerase activity, protein disulfide oxidoreductase activity Human GLRX3 IntAct UniProtKB {GO:0005515=PMID:10636891, GO:0010614=GO_REF:0000024, GO:0030018=GO_REF:0000039, GO:0051536=GO_REF:0000037, GO:0002026=PMID:18258855, GO:0005080=GO_REF:0000019, GO:0015035=GO_REF:0000002, GO:0009055=GO_REF:0000002, GO:0045454=GO_REF:0000002, GO:0005938=GO_REF:0000039, GO:0046872=GO_REF:0000037} O76003 Glutaredoxin-3 protein 20130415 {GO:0005515=IPI, GO:0010614=ISS, GO:0030018=IEA, GO:0051536=IEA, GO:0002026=ISS, GO:0005080=IEA, GO:0015035=IEA, GO:0009055=IEA, GO:0045454=IEA, GO:0005938=IEA, GO:0046872=IEA} cell redox homeostasis, negative regulation of cardiac muscle hypertrophy, regulation of the force of heart contraction Z disc, cell cortex electron carrier activity, iron-sulfur cluster binding, metal ion binding, protein binding, protein disulfide oxidoreductase activity, protein kinase C binding Human UniProtKB:Q04759 GLRX5 HPA UniProtKB {GO:0030097=GO_REF:0000024, GO:0005739=GO_REF:0000052, GO:0051537=GO_REF:0000037, GO:0015035=GO_REF:0000002, GO:0009055=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0045454=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q86SX6 Glutaredoxin-related protein 5, mitochondrial protein 20110516 {GO:0030097=ISS, GO:0005739=IDA, GO:0051537=IEA, GO:0015035=IEA, GO:0009055=IEA, GO:0005634=IDA, GO:0045454=IEA, GO:0046872=IEA} cell redox homeostasis, hemopoiesis mitochondrion, nucleus 2 iron, 2 sulfur cluster binding, electron carrier activity, metal ion binding, protein disulfide oxidoreductase activity Human GLS BHF-UCL UniProtKB {GO:0005515=PMID:16899818, GO:0006537=PMID:21757002, GO:0008652=Reactome:REACT_238, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0014047=Reactome:REACT_12591, GO:0007269=Reactome:REACT_13723, GO:0005829=GO_REF:0000039, GO:0005739=PMID:16899818, GO:0034641=Reactome:REACT_13, GO:0002087=GO_REF:0000019, GO:0051289=PMID:22049910, GO:0005759=Reactome:REACT_1700, GO:0004359=PMID:22049910, GO:0006543=PMID:22049910, GO:0007610=GO_REF:0000019, GO:0006541=GO_REF:0000002} O94925 Glutaminase kidney isoform, mitochondrial protein 20111201 {GO:0005515=IPI, GO:0006537=TAS, GO:0008652=TAS, GO:0007268=TAS, GO:0044281=TAS, GO:0014047=TAS, GO:0007269=TAS, GO:0005829=IEA, GO:0005739=IDA, GO:0034641=TAS, GO:0002087=IEA, GO:0051289=IDA, GO:0005759=TAS, GO:0004359=IDA, GO:0006543=IDA, GO:0007610=IEA, GO:0006541=IEA} behavior, cellular amino acid biosynthetic process, cellular nitrogen compound metabolic process, glutamate biosynthetic process, glutamate secretion, glutamine catabolic process, glutamine metabolic process, neurotransmitter secretion, protein homotetramerization, regulation of respiratory gaseous exchange by neurological system process, small molecule metabolic process, synaptic transmission cytosol, mitochondrial matrix, mitochondrion glutaminase activity, protein binding Human GLS2 Reactome UniProtKB {GO:0005515=PMID:11163757, GO:0006520=PMID:10620514, GO:0072593=PMID:20351271, GO:0007268=Reactome:REACT_13685, GO:0008652=Reactome:REACT_238, GO:0042981=PMID:20351271, GO:0044281=Reactome:REACT_111217, GO:0014047=Reactome:REACT_12591, GO:0007269=Reactome:REACT_13723, GO:0005739=PMID:20351271, GO:0034641=Reactome:REACT_13, GO:0005759=Reactome:REACT_1700, GO:0004359=GO_REF:0000003, GO:0006541=GO_REF:0000002} Q9UI32 Glutaminase liver isoform, mitochondrial protein 20130213 {GO:0005515=IPI, GO:0006520=TAS, GO:0072593=IMP, GO:0007268=TAS, GO:0008652=TAS, GO:0042981=IMP, GO:0044281=TAS, GO:0014047=TAS, GO:0007269=TAS, GO:0005739=IDA, GO:0034641=TAS, GO:0005759=TAS, GO:0004359=IEA, GO:0006541=IEA} cellular amino acid biosynthetic process, cellular amino acid metabolic process, cellular nitrogen compound metabolic process, glutamate secretion, glutamine metabolic process, neurotransmitter secretion, reactive oxygen species metabolic process, regulation of apoptotic process, small molecule metabolic process, synaptic transmission mitochondrial matrix, mitochondrion glutaminase activity, protein binding Human GLT8D1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0016757=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q68CQ7 Glycosyltransferase 8 domain-containing protein 1 protein 20080205 {GO:0005739=IDA, GO:0016757=IEA, GO:0016021=IEA} integral to membrane, mitochondrion transferase activity, transferring glycosyl groups Human GLT8D2 UniProtKB UniProtKB {GO:0016757=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q9H1C3 Glycosyltransferase 8 domain-containing protein 2 protein 20130413 {GO:0016757=IEA, GO:0016021=IEA} integral to membrane transferase activity, transferring glycosyl groups Human UniProtKB-KW:KW-0328 GLTP HGNC UniProtKB {GO:0005737=GO_REF:0000039, GO:0051861=PMID:15287756, GO:0016020=PMID:15901739, GO:0017089=PMID:15901739, GO:0046836=PMID:15901739, GO:0008289=PMID:15901739} Q9NZD2 Glycolipid transfer protein protein 20070412 {GO:0005737=IEA, GO:0051861=IDA, GO:0016020=IC, GO:0017089=IDA, GO:0046836=IDA, GO:0008289=IDA} glycolipid transport cytoplasm, membrane glycolipid binding, glycolipid transporter activity, lipid binding Human GLTPD1 InterPro UniProtKB {GO:0005737=GO_REF:0000002, GO:0051861=GO_REF:0000002, GO:0017089=GO_REF:0000002, GO:0046836=GO_REF:0000002} Q5TA50 Glycolipid transfer protein domain-containing protein 1 protein 20130413 {GO:0005737=IEA, GO:0051861=IEA, GO:0017089=IEA, GO:0046836=IEA} glycolipid transport cytoplasm glycolipid binding, glycolipid transporter activity Human InterPro:IPR014830 GLTPD2 InterPro UniProtKB {GO:0005737=GO_REF:0000002, GO:0051861=GO_REF:0000002, GO:0017089=GO_REF:0000002, GO:0046836=GO_REF:0000002} A6NH11 Glycolipid transfer protein domain-containing protein 2 protein 20130413 {GO:0005737=IEA, GO:0051861=IEA, GO:0017089=IEA, GO:0046836=IEA} glycolipid transport cytoplasm glycolipid binding, glycolipid transporter activity Human InterPro:IPR014830 GLTSCR1 IntAct UniProtKB {GO:0005515=PMID:17474147} Q9NZM4 Glioma tumor suppressor candidate region gene 1 protein protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:P16333 GLTSCR2 HPA UniProtKB {GO:0005622=PMID:10196275, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005730=GO_REF:0000052, GO:0043231=GO_REF:0000052} Q9NZM5 Glioma tumor suppressor candidate region gene 2 protein protein 20101115 {GO:0005622=NAS, GO:0008150=ND, GO:0003674=ND, GO:0005730=IDA, GO:0043231=IDA} biological_process intracellular, intracellular membrane-bounded organelle, nucleolus molecular_function Human GLUD1 HPA UniProtKB {GO:0005515=PMID:16959573, GO:0006520=GO_REF:0000002, GO:0006537=PMID:11032875, GO:0006538=PMID:11032875, GO:0070728=PMID:12742085, GO:0008652=Reactome:REACT_238, GO:0070403=PMID:12193607, GO:0016639=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0005525=PMID:11032875, GO:0005524=GO_REF:0000037, GO:0042802=PMID:11903050, GO:0005739=GO_REF:0000052, GO:0004352=PMID:11903050, GO:0004353=PMID:11032875, GO:0034641=Reactome:REACT_13, GO:0005737=PMID:18688271, GO:0043531=PMID:12742085, GO:0005759=Reactome:REACT_1896, GO:0032024=PMID:11502802} P00367 Glutamate dehydrogenase 1, mitochondrial protein 20111111 {GO:0005515=IPI, GO:0006520=IEA, GO:0006537=IDA, GO:0006538=IDA, GO:0070728=IDA, GO:0008652=TAS, GO:0070403=IDA, GO:0016639=IEA, GO:0044281=TAS, GO:0005525=IDA, GO:0005524=IEA, GO:0042802=TAS, GO:0005739=IDA, GO:0004352=IDA, GO:0004353=IDA, GO:0034641=TAS, GO:0005737=IDA, GO:0043531=IDA, GO:0005759=TAS, GO:0032024=IMP} cellular amino acid biosynthetic process, cellular amino acid metabolic process, cellular nitrogen compound metabolic process, glutamate biosynthetic process, glutamate catabolic process, positive regulation of insulin secretion, small molecule metabolic process cytoplasm, mitochondrial matrix, mitochondrion "ADP binding, ATP binding, GTP binding, NAD+ binding, glutamate dehydrogenase (NAD+) activity, glutamate dehydrogenase NAD(P)+"" activity, identical protein binding, leucine binding, oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor, protein binding""" Human GLUD2 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0004352=PMID:8207021, GO:0004353=PMID:11032875, GO:0005737=PMID:18688271, GO:0043531=PMID:12742085, GO:0006536=PMID:8207021, GO:0006537=PMID:11032875, GO:0006538=PMID:11032875, GO:0070728=PMID:12742085, GO:0005525=PMID:11032875, GO:0055114=PMID:8207021} P49448 Glutamate dehydrogenase 2, mitochondrial protein 20111111 {GO:0005739=IDA, GO:0004352=IDA, GO:0004353=IDA, GO:0005737=IDA, GO:0043531=IDA, GO:0006536=IDA, GO:0006537=IDA, GO:0006538=IDA, GO:0070728=IDA, GO:0005525=IDA, GO:0055114=IDA} glutamate biosynthetic process, glutamate catabolic process, glutamate metabolic process, oxidation-reduction process cytoplasm, mitochondrion "ADP binding, GTP binding, glutamate dehydrogenase (NAD+) activity, glutamate dehydrogenase NAD(P)+"" activity, leucine binding""" Human GLUL BHF-UCL UniProtKB {GO:0008283=PMID:18662667, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_1171, GO:0042802=PMID:21988832, GO:0005739=GO_REF:0000039, GO:0034641=Reactome:REACT_13, GO:0004351=GO_REF:0000003, GO:0004356=Reactome:REACT_1171, GO:0043204=GO_REF:0000019, GO:0051260=GO_REF:0000019, GO:0043679=GO_REF:0000019, GO:0032024=GO_REF:0000019, GO:0050679=GO_REF:0000019, GO:0005791=GO_REF:0000019, GO:0030145=GO_REF:0000019, GO:0000287=GO_REF:0000019, GO:0006538=PMID:21757002, GO:0051968=GO_REF:0000019, GO:0008652=Reactome:REACT_238, GO:0005524=GO_REF:0000019, GO:0009749=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0045503=GO_REF:0000019, GO:0001504=Reactome:REACT_13594, GO:0016595=GO_REF:0000019, GO:0006542=PMID:21757002} P15104 Glutamine synthetase protein 20111201 {GO:0008283=IDA, GO:0007268=TAS, GO:0044281=TAS, GO:0005829=TAS, GO:0042802=IPI, GO:0005739=IEA, GO:0034641=TAS, GO:0004351=IEA, GO:0004356=EXP, GO:0043204=IEA, GO:0051260=IEA, GO:0043679=IEA, GO:0032024=IEA, GO:0050679=IEA, GO:0005791=IEA, GO:0030145=IEA, GO:0000287=IEA, GO:0006538=TAS, GO:0051968=IEA, GO:0008652=TAS, GO:0005524=IEA, GO:0009749=IEA, GO:0043234=IEA, GO:0045503=IEA, GO:0001504=TAS, GO:0016595=IEA, GO:0006542=TAS} cell proliferation, cellular amino acid biosynthetic process, cellular nitrogen compound metabolic process, glutamate catabolic process, glutamine biosynthetic process, neurotransmitter uptake, positive regulation of epithelial cell proliferation, positive regulation of insulin secretion, positive regulation of synaptic transmission, glutamatergic, protein homooligomerization, response to glucose stimulus, small molecule metabolic process, synaptic transmission axon terminus, cytosol, mitochondrion, perikaryon, protein complex, rough endoplasmic reticulum ATP binding, dynein light chain binding, glutamate binding, glutamate decarboxylase activity, glutamate-ammonia ligase activity, identical protein binding, magnesium ion binding, manganese ion binding Human GLYAT Reactome UniProtKB {GO:0005739=GO_REF:0000024, GO:0006637=PMID:7802672, GO:0032787=GO_REF:0000024, GO:0006805=Reactome:REACT_13433, GO:0016746=PMID:9202629, GO:0005759=Reactome:REACT_6953, GO:0047961=GO_REF:0000003, GO:0006544=GO_REF:0000024, GO:0009636=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0047962=GO_REF:0000024} Q6IB77 Glycine N-acyltransferase protein 20130301 {GO:0005739=ISS, GO:0006637=TAS, GO:0032787=ISS, GO:0006805=TAS, GO:0016746=TAS, GO:0005759=TAS, GO:0047961=IEA, GO:0006544=ISS, GO:0009636=IEA, GO:0044281=TAS, GO:0047962=ISS} acyl-CoA metabolic process, glycine metabolic process, monocarboxylic acid metabolic process, response to toxic substance, small molecule metabolic process, xenobiotic metabolic process mitochondrial matrix, mitochondrion glycine N-acyltransferase activity, glycine N-benzoyltransferase activity, transferase activity, transferring acyl groups Human GLYATL1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000002, GO:0047961=GO_REF:0000002, GO:0047946=GO_REF:0000003} Q969I3 Glycine N-acyltransferase-like protein 1 protein 20130413 {GO:0005739=IEA, GO:0047961=IEA, GO:0047946=IEA} mitochondrion glutamine N-acyltransferase activity, glycine N-acyltransferase activity Human EC:2.3.1.68 GLYATL3 InterPro UniProtKB {GO:0005739=GO_REF:0000002, GO:0047961=GO_REF:0000002} Q5SZD4 Glycine N-acyltransferase-like protein 3 protein 20130413 {GO:0005739=IEA, GO:0047961=IEA} mitochondrion glycine N-acyltransferase activity Human InterPro:IPR010313|InterPro:IPR015938 GLYCTK HPA UniProtKB {GO:0005515=PMID:19060904, GO:0005739=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0006468=PMID:16753811, GO:0005524=GO_REF:0000037, GO:0008887=PMID:16753811} Q8IVS8 Glycerate kinase protein 20101115 {GO:0005515=IPI, GO:0005739=IEA, GO:0005737=IDA, GO:0005794=IDA, GO:0006468=IDA, GO:0005524=IEA, GO:0008887=IDA} protein phosphorylation Golgi apparatus, cytoplasm, mitochondrion ATP binding, glycerate kinase activity, protein binding Human GLYR1 UniProtKB UniProtKB {GO:0050662=GO_REF:0000002, GO:0004616=GO_REF:0000002, GO:0016491=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0035064=PMID:20850016, GO:0006098=GO_REF:0000002, GO:0003677=GO_REF:0000037} Q49A26 Putative oxidoreductase GLYR1 protein 20101105 {GO:0050662=IEA, GO:0004616=IEA, GO:0016491=IEA, GO:0005634=IEA, GO:0035064=IDA, GO:0006098=IEA, GO:0003677=IEA} pentose-phosphate shunt nucleus DNA binding, coenzyme binding, methylated histone residue binding, oxidoreductase activity, phosphogluconate dehydrogenase (decarboxylating) activity Human GM2A HPA UniProtKB {GO:0004563=GO_REF:0000019, GO:0006665=Reactome:REACT_19323, GO:0009313=GO_REF:0000019, GO:0006687=Reactome:REACT_116105, GO:0019915=GO_REF:0000019, GO:0006689=GO_REF:0000019, GO:0030149=GO_REF:0000029, GO:0005730=GO_REF:0000052, GO:0019377=GO_REF:0000029, GO:0044281=Reactome:REACT_111217, GO:0005764=GO_REF:0000029, GO:0030290=GO_REF:0000029, GO:0043231=GO_REF:0000052, GO:0005739=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0007611=GO_REF:0000019, GO:0050885=GO_REF:0000019, GO:0043202=Reactome:REACT_115984} P17900 Ganglioside GM2 activator protein 20101115 {GO:0004563=IEA, GO:0006665=TAS, GO:0009313=IEA, GO:0006687=TAS, GO:0019915=IEA, GO:0006689=IEA, GO:0030149=NAS, GO:0005730=IDA, GO:0019377=NAS, GO:0044281=TAS, GO:0005764=NAS, GO:0030290=NAS, GO:0043231=IDA, GO:0005739=IEA, GO:0005737=IDA, GO:0007611=IEA, GO:0050885=IEA, GO:0043202=TAS} ganglioside catabolic process, glycolipid catabolic process, glycosphingolipid metabolic process, learning or memory, lipid storage, neuromuscular process controlling balance, oligosaccharide catabolic process, small molecule metabolic process, sphingolipid catabolic process, sphingolipid metabolic process cytoplasm, intracellular membrane-bounded organelle, lysosomal lumen, lysosome, mitochondrion, nucleolus beta-N-acetylhexosaminidase activity, sphingolipid activator protein activity Human GMCL1 UniProtKB UniProtKB {GO:0006355=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0005635=GO_REF:0000019, GO:0007283=GO_REF:0000037, GO:0016363=GO_REF:0000039, GO:0030154=GO_REF:0000037} Q96IK5 Germ cell-less protein-like 1 protein 20130413 {GO:0006355=IEA, GO:0007275=IEA, GO:0005635=IEA, GO:0007283=IEA, GO:0016363=IEA, GO:0030154=IEA} cell differentiation, multicellular organismal development, regulation of transcription, DNA-dependent, spermatogenesis nuclear envelope, nuclear matrix Human UniProtKB-SubCell:SL-0181 GMDS UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0050662=GO_REF:0000002, GO:0005737=PMID:9525924, GO:0007219=GO_REF:0000024, GO:0008446=PMID:9603974, GO:0019673=PMID:9603974, GO:0042351=PMID:9525924, GO:0070401=PMID:9525924} O60547 GDP-mannose 4,6 dehydratase protein 20110815 {GO:0005622=IEA, GO:0050662=IEA, GO:0005737=IC, GO:0007219=ISS, GO:0008446=IGI, GO:0019673=IGI, GO:0042351=IDA, GO:0070401=IDA} 'de novo' GDP-L-fucose biosynthetic process, GDP-mannose metabolic process, Notch signaling pathway cytoplasm, intracellular GDP-mannose 4,6-dehydratase activity, NADP+ binding, coenzyme binding Human UniProtKB:Q1LVF8 GMEB1 HPA UniProtKB {GO:0005737=GO_REF:0000039, GO:0003700=GO_REF:0000019, GO:0003713=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9Y692 Glucocorticoid modulatory element-binding protein 1 protein 20111111 {GO:0005737=IEA, GO:0003700=IEA, GO:0003713=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0046872=IEA, GO:0006351=IEA} transcription, DNA-dependent cytoplasm, nucleolus, nucleus DNA binding, metal ion binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity NOT Human GMEB2 HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0006366=PMID:10523663, GO:0003713=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q9UKD1 Glucocorticoid modulatory element-binding protein 2 protein 20101115 {GO:0006355=IEA, GO:0005737=IDA, GO:0006366=TAS, GO:0003713=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0046872=IEA} regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter cytoplasm, nucleolus, nucleus DNA binding, metal ion binding, transcription coactivator activity Human GMFB GOC UniProtKB {GO:0005622=GO_REF:0000002, GO:0007165=PMID:8798479, GO:0004860=PMID:8639570, GO:0006468=PMID:7598724, GO:0003779=GO_REF:0000002, GO:0006469=PMID:8639570, GO:0004871=PMID:8798479, GO:0043085=PMID:8798479, GO:0008047=PMID:8798479, GO:0008083=GO_REF:0000037, GO:0007399=PMID:1712830} P60983 Glia maturation factor beta protein 20130413 {GO:0005622=IEA, GO:0007165=TAS, GO:0004860=TAS, GO:0006468=TAS, GO:0003779=IEA, GO:0006469=TAS, GO:0004871=TAS, GO:0043085=TAS, GO:0008047=TAS, GO:0008083=IEA, GO:0007399=TAS} negative regulation of protein kinase activity, nervous system development, positive regulation of catalytic activity, protein phosphorylation, signal transduction intracellular actin binding, enzyme activator activity, growth factor activity, protein kinase inhibitor activity, signal transducer activity Human GMFG GOC UniProtKB {GO:0005622=GO_REF:0000002, GO:0004860=PMID:8639570, GO:0006468=PMID:7598724, GO:0003779=GO_REF:0000002, GO:0006469=PMID:8639570, GO:0043085=PMID:8798479, GO:0008047=PMID:8798479, GO:0008083=GO_REF:0000037} O60234 Glia maturation factor gamma protein 20130413 {GO:0005622=IEA, GO:0004860=TAS, GO:0006468=TAS, GO:0003779=IEA, GO:0006469=TAS, GO:0043085=TAS, GO:0008047=TAS, GO:0008083=IEA} negative regulation of protein kinase activity, positive regulation of catalytic activity, protein phosphorylation intracellular actin binding, enzyme activator activity, growth factor activity, protein kinase inhibitor activity Human GMIP GOC UniProtKB {GO:0005515=PMID:12093360, GO:0035556=PMID:12093360, GO:0005622=PMID:12093360, GO:0051056=Reactome:REACT_11051, GO:0032321=PMID:12093360, GO:0034259=PMID:12093360, GO:0007264=Reactome:REACT_11044, GO:0005100=PMID:12093360, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_9982} Q9P107 GEM-interacting protein protein 20130413 {GO:0005515=IPI, GO:0035556=IDA, GO:0005622=IC, GO:0051056=TAS, GO:0032321=IDA, GO:0034259=IDA, GO:0007264=TAS, GO:0005100=IDA, GO:0046872=IEA, GO:0005829=TAS} intracellular signal transduction, negative regulation of Rho GTPase activity, positive regulation of Rho GTPase activity, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol, intracellular Rho GTPase activator activity, metal ion binding, protein binding Human GMNN HPA UniProtKB {GO:0005515=PMID:21543332, GO:0042826=PMID:16924111, GO:0003714=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0045786=PMID:9635433, GO:0005829=Reactome:REACT_1787, GO:0005737=GO_REF:0000052, GO:0006461=GO_REF:0000019, GO:0070491=GO_REF:0000019, GO:0009887=GO_REF:0000019, GO:0005654=Reactome:REACT_757, GO:0008156=PMID:9635433, GO:0000278=Reactome:REACT_152, GO:0045892=PMID:16924111} O75496 Geminin protein 20120912 {GO:0005515=IPI, GO:0042826=IPI, GO:0003714=IEA, GO:0005634=IDA, GO:0045786=IDA, GO:0005829=TAS, GO:0005737=IDA, GO:0006461=IEA, GO:0070491=IEA, GO:0009887=IEA, GO:0005654=TAS, GO:0008156=IDA, GO:0000278=TAS, GO:0045892=IDA} mitotic cell cycle, negative regulation of DNA replication, negative regulation of cell cycle, negative regulation of transcription, DNA-dependent, organ morphogenesis, protein complex assembly cytoplasm, cytosol, nucleoplasm, nucleus histone deacetylase binding, protein binding, repressing transcription factor binding, transcription corepressor activity Human GMPPA Reactome UniProtKB {GO:0009058=GO_REF:0000002, GO:0016779=GO_REF:0000002, GO:0009298=Reactome:REACT_22423, GO:0006488=Reactome:REACT_22433, GO:0005525=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0004475=GO_REF:0000003, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q96IJ6 Mannose-1-phosphate guanyltransferase alpha protein 20130301 {GO:0009058=IEA, GO:0016779=IEA, GO:0009298=TAS, GO:0006488=TAS, GO:0005525=IEA, GO:0044267=TAS, GO:0004475=IEA, GO:0043687=TAS, GO:0018279=TAS} GDP-mannose biosynthetic process, biosynthetic process, cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine GTP binding, mannose-1-phosphate guanylyltransferase activity, nucleotidyltransferase activity Human GMPPB Reactome UniProtKB {GO:0005739=GO_REF:0000019, GO:0009298=Reactome:REACT_22423, GO:0006488=Reactome:REACT_22433, GO:0005525=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0004475=GO_REF:0000003, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q9Y5P6 Mannose-1-phosphate guanyltransferase beta protein 20130301 {GO:0005739=IEA, GO:0009298=TAS, GO:0006488=TAS, GO:0005525=IEA, GO:0044267=TAS, GO:0004475=IEA, GO:0043687=TAS, GO:0018279=TAS} GDP-mannose biosynthetic process, cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine mitochondrion GTP binding, mannose-1-phosphate guanylyltransferase activity Human GMPR Reactome UniProtKB {GO:0006144=Reactome:REACT_522, GO:0009409=PMID:9813009, GO:0043101=Reactome:REACT_1923, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0003920=GO_REF:0000003, GO:0046872=GO_REF:0000037, GO:0009117=GO_REF:0000002, GO:0005829=Reactome:REACT_21383} P36959 GMP reductase 1 protein 20130213 {GO:0006144=TAS, GO:0009409=TAS, GO:0043101=TAS, GO:0055086=TAS, GO:0044281=TAS, GO:0003920=IEA, GO:0046872=IEA, GO:0009117=IEA, GO:0005829=TAS} nucleobase-containing small molecule metabolic process, nucleotide metabolic process, purine nucleobase metabolic process, purine-containing compound salvage, response to cold, small molecule metabolic process cytosol GMP reductase activity, metal ion binding Human GMPR2 Reactome UniProtKB {GO:0006144=Reactome:REACT_522, GO:0043101=Reactome:REACT_1923, GO:0016491=GO_REF:0000002, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0003920=GO_REF:0000003, GO:0003824=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0009117=GO_REF:0000002, GO:0005829=Reactome:REACT_21383, GO:0055114=GO_REF:0000002} Q9P2T1 GMP reductase 2 protein 20130213 {GO:0006144=TAS, GO:0043101=TAS, GO:0016491=IEA, GO:0055086=TAS, GO:0044281=TAS, GO:0003920=IEA, GO:0003824=IEA, GO:0046872=IEA, GO:0009117=IEA, GO:0005829=TAS, GO:0055114=IEA} nucleobase-containing small molecule metabolic process, nucleotide metabolic process, oxidation-reduction process, purine nucleobase metabolic process, purine-containing compound salvage, small molecule metabolic process cytosol GMP reductase activity, catalytic activity, metal ion binding, oxidoreductase activity Human GMPS Reactome UniProtKB {GO:0016462=GO_REF:0000002, GO:0009168=Reactome:REACT_1776, GO:0006177=GO_REF:0000002, GO:0006144=Reactome:REACT_522, GO:0055086=Reactome:REACT_1698, GO:0009113=PMID:8089153, GO:0003922=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0003921=PMID:8089153, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_628, GO:0006541=GO_REF:0000037} P49915 "GMP synthase ""glutamine-hydrolyzing""" protein 20130301 {GO:0016462=IEA, GO:0009168=TAS, GO:0006177=IEA, GO:0006144=TAS, GO:0055086=TAS, GO:0009113=TAS, GO:0003922=IEA, GO:0044281=TAS, GO:0003921=TAS, GO:0005524=IEA, GO:0005829=TAS, GO:0006541=IEA} GMP biosynthetic process, glutamine metabolic process, nucleobase-containing small molecule metabolic process, purine nucleobase biosynthetic process, purine nucleobase metabolic process, purine ribonucleoside monophosphate biosynthetic process, small molecule metabolic process cytosol ATP binding, GMP synthase (glutamine-hydrolyzing) activity, GMP synthase activity, pyrophosphatase activity Human GNA11 Reactome UniProtKB {GO:0001664=GO_REF:0000033, GO:0005886=Reactome:REACT_23902, GO:0005834=GO_REF:0000033, GO:0003924=GO_REF:0000002, GO:0030168=Reactome:REACT_798, GO:0031683=GO_REF:0000033, GO:0005525=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0031234=GO_REF:0000033, GO:0007507=GO_REF:0000019, GO:0007165=PMID:8530500, GO:0005737=PMID:9175863, GO:0001501=GO_REF:0000019, GO:0007186=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0060158=GO_REF:0000033, GO:0045634=GO_REF:0000019, GO:0007188=GO_REF:0000033, GO:0004871=GO_REF:0000033, GO:0001508=GO_REF:0000033, GO:0048066=GO_REF:0000019} P29992 Guanine nucleotide-binding protein subunit alpha-11 protein 20130301 {GO:0001664=IBA, GO:0005886=TAS, GO:0005834=IBA, GO:0003924=IEA, GO:0030168=TAS, GO:0031683=IBA, GO:0005525=IEA, GO:0046872=IEA, GO:0031234=IBA, GO:0007507=IEA, GO:0007165=TAS, GO:0005737=TAS, GO:0001501=IEA, GO:0007186=IEA, GO:0007596=TAS, GO:0060158=IBA, GO:0045634=IEA, GO:0007188=IBA, GO:0004871=IBA, GO:0001508=IBA, GO:0048066=IEA} G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, blood coagulation, developmental pigmentation, heart development, phospholipase C-activating dopamine receptor signaling pathway, platelet activation, regulation of action potential, regulation of melanocyte differentiation, signal transduction, skeletal system development cytoplasm, extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, plasma membrane G-protein beta/gamma-subunit complex binding, G-protein coupled receptor binding, GTP binding, GTPase activity, metal ion binding, signal transducer activity Human GNA12 Reactome UniProtKB {GO:0005515=PMID:10026210, GO:0005886=Reactome:REACT_23796, GO:0007264=GO_REF:0000002, GO:0008360=GO_REF:0000019, GO:0003924=GO_REF:0000033, GO:0007266=GO_REF:0000033, GO:0031526=GO_REF:0000033, GO:0030154=GO_REF:0000019, GO:0007243=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0004871=GO_REF:0000033, GO:0001664=GO_REF:0000002, GO:0042493=GO_REF:0000019, GO:0005834=GO_REF:0000033, GO:0030168=Reactome:REACT_798, GO:0005525=GO_REF:0000037, GO:0031683=GO_REF:0000033, GO:0001701=GO_REF:0000019, GO:0031234=GO_REF:0000033, GO:0019001=GO_REF:0000002, GO:0007186=PMID:8290554, GO:0007596=Reactome:REACT_604, GO:0031752=GO_REF:0000033, GO:0007188=GO_REF:0000033, GO:0042733=GO_REF:0000019} Q03113 Guanine nucleotide-binding protein subunit alpha-12 protein 20130213 {GO:0005515=IPI, GO:0005886=TAS, GO:0007264=IEA, GO:0008360=IEA, GO:0003924=IBA, GO:0007266=IBA, GO:0031526=IBA, GO:0030154=IEA, GO:0007243=IEA, GO:0046872=IEA, GO:0004871=IBA, GO:0001664=IEA, GO:0042493=IEA, GO:0005834=IBA, GO:0030168=TAS, GO:0005525=IEA, GO:0031683=IBA, GO:0001701=IEA, GO:0031234=IBA, GO:0019001=IEA, GO:0007186=TAS, GO:0007596=TAS, GO:0031752=IBA, GO:0007188=IBA, GO:0042733=IEA} G-protein coupled receptor signaling pathway, Rho protein signal transduction, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, blood coagulation, cell differentiation, embryonic digit morphogenesis, in utero embryonic development, intracellular protein kinase cascade, platelet activation, regulation of cell shape, response to drug, small GTPase mediated signal transduction brush border membrane, extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, plasma membrane D5 dopamine receptor binding, G-protein beta/gamma-subunit complex binding, G-protein coupled receptor binding, GTP binding, GTPase activity, guanyl nucleotide binding, metal ion binding, protein binding, signal transducer activity Human GNA13 IntAct UniProtKB {GO:0005515=PMID:12681510, GO:0005886=Reactome:REACT_23796, GO:0008360=GO_REF:0000019, GO:0003924=GO_REF:0000033, GO:0006928=PMID:8999798, GO:0007266=GO_REF:0000033, GO:0031526=GO_REF:0000033, GO:0031702=GO_REF:0000033, GO:0046872=GO_REF:0000037, GO:0030154=GO_REF:0000019, GO:0007243=GO_REF:0000019, GO:0004871=GO_REF:0000033, GO:0030334=GO_REF:0000019, GO:0031584=GO_REF:0000033, GO:0042470=GO_REF:0000039, GO:0001569=GO_REF:0000019, GO:0001664=GO_REF:0000002, GO:0005834=GO_REF:0000033, GO:0030168=Reactome:REACT_798, GO:0005525=GO_REF:0000037, GO:0031683=GO_REF:0000033, GO:0001701=GO_REF:0000019, GO:0031234=GO_REF:0000033, GO:0007165=PMID:7791744, GO:0007596=Reactome:REACT_604, GO:0031752=GO_REF:0000033, GO:0007189=GO_REF:0000033} Q14344 Guanine nucleotide-binding protein subunit alpha-13 protein 20130415 {GO:0005515=IPI, GO:0005886=TAS, GO:0008360=IEA, GO:0003924=IBA, GO:0006928=TAS, GO:0007266=IBA, GO:0031526=IBA, GO:0031702=IBA, GO:0046872=IEA, GO:0030154=IEA, GO:0007243=IEA, GO:0004871=IBA, GO:0030334=IEA, GO:0031584=IBA, GO:0042470=IEA, GO:0001569=IEA, GO:0001664=IEA, GO:0005834=IBA, GO:0030168=TAS, GO:0005525=IEA, GO:0031683=IBA, GO:0001701=IEA, GO:0031234=IBA, GO:0007165=TAS, GO:0007596=TAS, GO:0031752=IBA, GO:0007189=IBA} Rho protein signal transduction, activation of phospholipase D activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, blood coagulation, cell differentiation, cellular component movement, in utero embryonic development, intracellular protein kinase cascade, patterning of blood vessels, platelet activation, regulation of cell migration, regulation of cell shape, signal transduction brush border membrane, extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, melanosome, plasma membrane D5 dopamine receptor binding, G-protein beta/gamma-subunit complex binding, G-protein coupled receptor binding, GTP binding, GTPase activity, metal ion binding, protein binding, signal transducer activity, type 1 angiotensin receptor binding Human UniProtKB:Q92888 GNA14 Reactome UniProtKB {GO:0001664=GO_REF:0000033, GO:0005886=Reactome:REACT_23902, GO:0005834=GO_REF:0000033, GO:0003924=GO_REF:0000002, GO:0030168=Reactome:REACT_798, GO:0005525=GO_REF:0000037, GO:0031683=GO_REF:0000033, GO:0046872=GO_REF:0000037, GO:0031234=GO_REF:0000033, GO:0007165=PMID:10191087, GO:0007596=Reactome:REACT_604, GO:0060158=GO_REF:0000033, GO:0007188=GO_REF:0000033, GO:0004871=GO_REF:0000033} O95837 Guanine nucleotide-binding protein subunit alpha-14 protein 20130301 {GO:0001664=IBA, GO:0005886=TAS, GO:0005834=IBA, GO:0003924=IEA, GO:0030168=TAS, GO:0005525=IEA, GO:0031683=IBA, GO:0046872=IEA, GO:0031234=IBA, GO:0007165=TAS, GO:0007596=TAS, GO:0060158=IBA, GO:0007188=IBA, GO:0004871=IBA} adenylate cyclase-modulating G-protein coupled receptor signaling pathway, blood coagulation, phospholipase C-activating dopamine receptor signaling pathway, platelet activation, signal transduction extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, plasma membrane G-protein beta/gamma-subunit complex binding, G-protein coupled receptor binding, GTP binding, GTPase activity, metal ion binding, signal transducer activity Human GNA15 Reactome UniProtKB {GO:0001664=GO_REF:0000033, GO:0005886=Reactome:REACT_23902, GO:0005834=PMID:10571060, GO:0003924=GO_REF:0000002, GO:0030168=Reactome:REACT_798, GO:0007202=PMID:7797501, GO:0031683=GO_REF:0000033, GO:0005525=GO_REF:0000029, GO:0007204=PMID:10571060, GO:0046872=GO_REF:0000037, GO:0031234=GO_REF:0000033, GO:0019001=GO_REF:0000002, GO:0007186=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0007207=PMID:7797501, GO:0060158=GO_REF:0000033, GO:0007188=GO_REF:0000033, GO:0004871=PMID:10571060} P30679 Guanine nucleotide-binding protein subunit alpha-15 protein 20130301 {GO:0001664=IBA, GO:0005886=TAS, GO:0005834=NAS, GO:0003924=IEA, GO:0030168=TAS, GO:0007202=TAS, GO:0031683=IBA, GO:0005525=NAS, GO:0007204=IGI, GO:0046872=IEA, GO:0031234=IBA, GO:0019001=IEA, GO:0007186=IEA, GO:0007596=TAS, GO:0007207=TAS, GO:0060158=IBA, GO:0007188=IBA, GO:0004871=IGI} G-protein coupled receptor signaling pathway, activation of phospholipase C activity, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, blood coagulation, elevation of cytosolic calcium ion concentration, phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway, phospholipase C-activating dopamine receptor signaling pathway, platelet activation extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, plasma membrane G-protein beta/gamma-subunit complex binding, G-protein coupled receptor binding, GTP binding, GTPase activity, guanyl nucleotide binding, metal ion binding, signal transducer activity Human GNAI1 BHF-UCL UniProtKB {GO:0005515=PMID:15537540, GO:0005886=GO_REF:0000054, GO:0003924=Reactome:REACT_15495, GO:0043434=GO_REF:0000024, GO:0007268=Reactome:REACT_13685, GO:0005634=GO_REF:0000039, GO:0006906=GO_REF:0000019, GO:0007193=Reactome:REACT_15333, GO:0046872=GO_REF:0000037, GO:0005622=GO_REF:0000019, GO:0005737=PMID:17635935, GO:0004871=GO_REF:0000033, GO:0005813=PMID:17635935, GO:0005794=GO_REF:0000019, GO:0005834=GO_REF:0000033, GO:0030168=Reactome:REACT_798, GO:0030496=PMID:17635935, GO:0031683=GO_REF:0000033, GO:0005525=GO_REF:0000024, GO:0031234=GO_REF:0000033, GO:0042588=GO_REF:0000019, GO:0019001=GO_REF:0000002, GO:0007049=GO_REF:0000037, GO:0007186=GO_REF:0000024, GO:0007596=Reactome:REACT_604, GO:0045121=GO_REF:0000019, GO:0031821=GO_REF:0000033, GO:0007188=GO_REF:0000002, GO:0051301=PMID:17635935} P63096 Guanine nucleotide-binding protein G(i) subunit alpha-1 protein 20120510 {GO:0005515=IPI, GO:0005886=IDA, GO:0003924=TAS, GO:0043434=ISS, GO:0007268=TAS, GO:0005634=IEA, GO:0006906=IEA, GO:0007193=TAS, GO:0046872=IEA, GO:0005622=IEA, GO:0005737=IDA, GO:0004871=IBA, GO:0005813=IDA, GO:0005794=IEA, GO:0005834=IBA, GO:0030168=TAS, GO:0030496=IDA, GO:0031683=IBA, GO:0005525=ISS, GO:0031234=IBA, GO:0042588=IEA, GO:0019001=IEA, GO:0007049=IEA, GO:0007186=ISS, GO:0007596=TAS, GO:0045121=IEA, GO:0031821=IBA, GO:0007188=IEA, GO:0051301=IMP} G-protein coupled receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, blood coagulation, cell cycle, cell division, platelet activation, response to peptide hormone stimulus, synaptic transmission, vesicle fusion Golgi apparatus, centrosome, cytoplasm, extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, intracellular, membrane raft, midbody, nucleus, plasma membrane, zymogen granule G-protein beta/gamma-subunit complex binding, G-protein coupled serotonin receptor binding, GTP binding, GTPase activity, guanyl nucleotide binding, metal ion binding, protein binding, signal transducer activity Human UniProtKB:G1SEJ8 GNAI2 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0008284=GO_REF:0000019, GO:0005886=Reactome:REACT_22335, GO:0008283=GO_REF:0000019, GO:0003924=GO_REF:0000033, GO:0007268=Reactome:REACT_13685, GO:0005634=GO_REF:0000019, GO:0007194=PMID:9637720, GO:0007193=Reactome:REACT_15333, GO:0007243=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=GO_REF:0000019, GO:0005737=PMID:17635935, GO:0000186=GO_REF:0000019, GO:0051924=GO_REF:0000019, GO:0004871=GO_REF:0000033, GO:0005813=PMID:17635935, GO:0001664=GO_REF:0000033, GO:0007584=PMID:8587610, GO:0005834=GO_REF:0000033, GO:0030168=Reactome:REACT_798, GO:0030496=PMID:17635935, GO:0007214=GO_REF:0000033, GO:0005525=GO_REF:0000037, GO:0031683=GO_REF:0000033, GO:0007213=GO_REF:0000019, GO:0031234=GO_REF:0000033, GO:0007165=PMID:9637720, GO:0007049=GO_REF:0000037, GO:0019001=GO_REF:0000002, GO:0001973=GO_REF:0000033, GO:0007186=PMID:8587610, GO:0007596=Reactome:REACT_604, GO:0050805=GO_REF:0000019, GO:0007188=GO_REF:0000002, GO:0045121=GO_REF:0000019, GO:0051301=PMID:17635935} P04899 Guanine nucleotide-binding protein G(i) subunit alpha-2 protein 20130415 {GO:0005515=IPI, GO:0008284=IEA, GO:0005886=TAS, GO:0008283=IEA, GO:0003924=IBA, GO:0007268=TAS, GO:0005634=IEA, GO:0007194=TAS, GO:0007193=TAS, GO:0007243=IEA, GO:0046872=IEA, GO:0005829=IEA, GO:0005737=IDA, GO:0000186=IEA, GO:0051924=IEA, GO:0004871=IBA, GO:0005813=IDA, GO:0001664=IBA, GO:0007584=TAS, GO:0005834=IBA, GO:0030168=TAS, GO:0030496=IDA, GO:0007214=IBA, GO:0005525=IEA, GO:0031683=IBA, GO:0007213=IEA, GO:0031234=IBA, GO:0007165=TAS, GO:0007049=IEA, GO:0019001=IEA, GO:0001973=IBA, GO:0007186=TAS, GO:0007596=TAS, GO:0050805=IEA, GO:0007188=IEA, GO:0045121=IEA, GO:0051301=IMP} G-protein coupled acetylcholine receptor signaling pathway, G-protein coupled receptor signaling pathway, activation of MAPKK activity, adenosine receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, blood coagulation, cell cycle, cell division, cell proliferation, gamma-aminobutyric acid signaling pathway, intracellular protein kinase cascade, negative regulation of adenylate cyclase activity, negative regulation of synaptic transmission, platelet activation, positive regulation of cell proliferation, regulation of calcium ion transport, response to nutrient, signal transduction, synaptic transmission centrosome, cytoplasm, cytosol, extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, membrane raft, midbody, nucleus, plasma membrane G-protein beta/gamma-subunit complex binding, G-protein coupled receptor binding, GTP binding, GTPase activity, guanyl nucleotide binding, metal ion binding, protein binding, signal transducer activity Human UniProtKB:Q99750 GNAI3 Reactome UniProtKB {GO:0005813=PMID:17635935, GO:0005794=GO_REF:0000019, GO:0005886=Reactome:REACT_22335, GO:0005834=GO_REF:0000033, GO:0003924=GO_REF:0000033, GO:0030168=Reactome:REACT_798, GO:0007268=Reactome:REACT_13685, GO:0030496=PMID:17635935, GO:0007194=PMID:7608168, GO:0005525=GO_REF:0000037, GO:0031683=GO_REF:0000033, GO:0007193=Reactome:REACT_15333, GO:0006906=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0031234=GO_REF:0000033, GO:0042588=GO_REF:0000019, GO:0005737=PMID:17635935, GO:0007049=GO_REF:0000037, GO:0007596=Reactome:REACT_604, GO:0006810=PMID:2452165, GO:0045121=GO_REF:0000019, GO:0031821=GO_REF:0000033, GO:0004871=GO_REF:0000033, GO:0051301=PMID:17635935} P08754 Guanine nucleotide-binding protein G(k) subunit alpha protein 20130301 {GO:0005813=IDA, GO:0005794=IEA, GO:0005886=TAS, GO:0005834=IBA, GO:0003924=IBA, GO:0030168=TAS, GO:0007268=TAS, GO:0030496=IDA, GO:0007194=TAS, GO:0005525=IEA, GO:0031683=IBA, GO:0007193=TAS, GO:0006906=IEA, GO:0046872=IEA, GO:0031234=IBA, GO:0042588=IEA, GO:0005737=IDA, GO:0007049=IEA, GO:0007596=TAS, GO:0006810=NAS, GO:0045121=IEA, GO:0031821=IBA, GO:0004871=IBA, GO:0051301=IDA} adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, blood coagulation, cell cycle, cell division, negative regulation of adenylate cyclase activity, platelet activation, synaptic transmission, transport, vesicle fusion Golgi apparatus, centrosome, cytoplasm, extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, membrane raft, midbody, plasma membrane, zymogen granule G-protein beta/gamma-subunit complex binding, G-protein coupled serotonin receptor binding, GTP binding, GTPase activity, metal ion binding, signal transducer activity Human GNAL Reactome UniProtKB {GO:0007608=GO_REF:0000033, GO:0001664=GO_REF:0000033, GO:0005886=Reactome:REACT_15547, GO:0005834=GO_REF:0000033, GO:0003924=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0031683=GO_REF:0000033, GO:0005525=GO_REF:0000037, GO:0007193=Reactome:REACT_15333, GO:0046872=GO_REF:0000037, GO:0031234=GO_REF:0000033, GO:0007191=GO_REF:0000033, GO:0007165=PMID:8243272, GO:0007190=GO_REF:0000019, GO:0001975=GO_REF:0000019, GO:0031000=GO_REF:0000019, GO:0007186=GO_REF:0000002, GO:0007189=Reactome:REACT_15312, GO:0004871=GO_REF:0000033} P38405 Guanine nucleotide-binding protein G(olf) subunit alpha protein 20130213 {GO:0007608=IBA, GO:0001664=IBA, GO:0005886=TAS, GO:0005834=IBA, GO:0003924=IEA, GO:0007268=TAS, GO:0031683=IBA, GO:0005525=IEA, GO:0007193=TAS, GO:0046872=IEA, GO:0031234=IBA, GO:0007191=IBA, GO:0007165=TAS, GO:0007190=IEA, GO:0001975=IEA, GO:0031000=IEA, GO:0007186=IEA, GO:0007189=TAS, GO:0004871=IBA} G-protein coupled receptor signaling pathway, activation of adenylate cyclase activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-activating dopamine receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, response to amphetamine, response to caffeine, sensory perception of smell, signal transduction, synaptic transmission extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, plasma membrane G-protein beta/gamma-subunit complex binding, G-protein coupled receptor binding, GTP binding, GTPase activity, metal ion binding, signal transducer activity Human GNAO1 Reactome UniProtKB {GO:0042542=GO_REF:0000019, GO:0043005=GO_REF:0000019, GO:0005886=Reactome:REACT_15549, GO:0031852=GO_REF:0000019, GO:0008016=GO_REF:0000019, GO:0003924=GO_REF:0000033, GO:0046872=GO_REF:0000037, GO:0031175=GO_REF:0000019, GO:0005622=GO_REF:0000019, GO:0006936=PMID:9050846, GO:0007626=GO_REF:0000019, GO:0051926=GO_REF:0000019, GO:0004871=GO_REF:0000033, GO:0034097=GO_REF:0000019, GO:0051430=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0005834=GO_REF:0000033, GO:0007568=GO_REF:0000019, GO:0043278=GO_REF:0000019, GO:0007212=GO_REF:0000033, GO:0005525=GO_REF:0000019, GO:0031683=GO_REF:0000033, GO:0031234=GO_REF:0000033, GO:0043547=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0007186=GO_REF:0000002, GO:0007188=GO_REF:0000033, GO:0031821=GO_REF:0000033, GO:0030900=GO_REF:0000019} P09471 Guanine nucleotide-binding protein G(o) subunit alpha protein 20130123 {GO:0042542=IEA, GO:0043005=IEA, GO:0005886=TAS, GO:0031852=IEA, GO:0008016=IEA, GO:0003924=IBA, GO:0046872=IEA, GO:0031175=IEA, GO:0005622=IEA, GO:0006936=TAS, GO:0007626=IEA, GO:0051926=IEA, GO:0004871=IBA, GO:0034097=IEA, GO:0051430=IEA, GO:0042493=IEA, GO:0005834=IBA, GO:0007568=IEA, GO:0043278=IEA, GO:0007212=IBA, GO:0005525=IEA, GO:0031683=IBA, GO:0031234=IBA, GO:0043547=IEA, GO:0043234=IEA, GO:0016020=IEA, GO:0007186=IEA, GO:0007188=IBA, GO:0031821=IBA, GO:0030900=IEA} G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, aging, dopamine receptor signaling pathway, forebrain development, locomotory behavior, muscle contraction, negative regulation of calcium ion transport, neuron projection development, positive regulation of GTPase activity, regulation of heart contraction, response to cytokine stimulus, response to drug, response to hydrogen peroxide, response to morphine extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, intracellular, membrane, neuron projection, plasma membrane, protein complex G-protein beta/gamma-subunit complex binding, G-protein coupled serotonin receptor binding, GTP binding, GTPase activity, corticotropin-releasing hormone receptor 1 binding, metal ion binding, mu-type opioid receptor binding, signal transducer activity Human GNAQ GOC UniProtKB {GO:0005515=PMID:18672896, GO:0005886=Reactome:REACT_23902, GO:0003924=GO_REF:0000002, GO:0007202=PMID:8825633, GO:0009791=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0035412=PMID:20399743, GO:0007507=GO_REF:0000019, GO:0016322=GO_REF:0000019, GO:0005737=PMID:9175863, GO:0007610=GO_REF:0000019, GO:0045634=GO_REF:0000019, GO:0004871=GO_REF:0000033, GO:0048066=GO_REF:0000019, GO:0031965=GO_REF:0000039, GO:0001664=GO_REF:0000033, GO:0005834=GO_REF:0000033, GO:0050821=PMID:20399743, GO:0030168=Reactome:REACT_798, GO:0007215=GO_REF:0000033, GO:0005525=GO_REF:0000037, GO:0031683=GO_REF:0000033, GO:0031234=GO_REF:0000033, GO:0043547=PMID:15611106, GO:0001501=GO_REF:0000019, GO:0007186=GO_REF:0000002, GO:0016020=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0060158=GO_REF:0000033, GO:0006469=PMID:20399743, GO:0007189=GO_REF:0000033, GO:0001508=GO_REF:0000033, GO:0021884=GO_REF:0000019, GO:0042733=GO_REF:0000019, GO:0005096=PMID:15611106} P50148 Guanine nucleotide-binding protein G(q) subunit alpha protein 20130413 {GO:0005515=IPI, GO:0005886=TAS, GO:0003924=IEA, GO:0007202=TAS, GO:0009791=IEA, GO:0046872=IEA, GO:0035412=IMP, GO:0007507=IEA, GO:0016322=IEA, GO:0005737=TAS, GO:0007610=IEA, GO:0045634=IEA, GO:0004871=IBA, GO:0048066=IEA, GO:0031965=IEA, GO:0001664=IBA, GO:0005834=IBA, GO:0050821=IMP, GO:0030168=TAS, GO:0007215=IBA, GO:0005525=IEA, GO:0031683=IBA, GO:0031234=IBA, GO:0043547=IDA, GO:0001501=IEA, GO:0007186=IEA, GO:0016020=IEA, GO:0007596=TAS, GO:0060158=IBA, GO:0006469=IMP, GO:0007189=IBA, GO:0001508=IBA, GO:0021884=IEA, GO:0042733=IEA, GO:0005096=IDA} G-protein coupled receptor signaling pathway, activation of phospholipase C activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, behavior, blood coagulation, developmental pigmentation, embryonic digit morphogenesis, forebrain neuron development, glutamate receptor signaling pathway, heart development, negative regulation of protein kinase activity, neuron remodeling, phospholipase C-activating dopamine receptor signaling pathway, platelet activation, positive regulation of GTPase activity, post-embryonic development, protein stabilization, regulation of action potential, regulation of catenin import into nucleus, regulation of melanocyte differentiation, skeletal system development cytoplasm, extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, membrane, nuclear membrane, plasma membrane G-protein beta/gamma-subunit complex binding, G-protein coupled receptor binding, GTP binding, GTPase activator activity, GTPase activity, metal ion binding, protein binding, signal transducer activity Human GNAS BHF-UCL UniProtKB {GO:0007608=PMID:3018580, GO:0009306=PMID:10729789, GO:0051216=GO_REF:0000019, GO:0007606=GO_REF:0000033, GO:0031224=PMID:7997272, GO:0048701=GO_REF:0000019, GO:0001894=GO_REF:0000019, GO:0007610=GO_REF:0000019, GO:0006833=Reactome:REACT_24023, GO:0007565=PMID:10729789, GO:0031683=GO_REF:0000033, GO:0031234=GO_REF:0000033, GO:0001958=GO_REF:0000019, GO:0007186=GO_REF:0000002, GO:0071870=GO_REF:0000024, GO:0043588=GO_REF:0000019, GO:0030133=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0031852=GO_REF:0000033, GO:0003924=GO_REF:0000033, GO:0044281=Reactome:REACT_111217, GO:0071380=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0030425=GO_REF:0000019, GO:0005829=GO_REF:0000024, GO:0007191=GO_REF:0000033, GO:0007190=PMID:9159128, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000054, GO:0035264=GO_REF:0000019, GO:0071377=Reactome:REACT_1665, GO:0071514=GO_REF:0000019, GO:0006171=Reactome:REACT_18321, GO:0004871=GO_REF:0000033, GO:0042493=GO_REF:0000019, GO:0005834=GO_REF:0000033, GO:0045672=GO_REF:0000019, GO:0046907=PMID:7997272, GO:0005576=GO_REF:0000029, GO:0005525=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0001726=GO_REF:0000039, GO:0032588=PMID:7997272, GO:0006306=GO_REF:0000019, GO:0040032=GO_REF:0000019, GO:0045669=GO_REF:0000019, GO:0019001=GO_REF:0000002, GO:0006112=GO_REF:0000019, GO:0004016=Reactome:REACT_18321, GO:0016020=GO_REF:0000024, GO:0035255=GO_REF:0000033, GO:0050796=Reactome:REACT_18325, GO:0007596=Reactome:REACT_604, GO:0035116=GO_REF:0000019} Q5JWF2 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas protein 20120323 {GO:0007608=TAS, GO:0009306=NAS, GO:0051216=IEA, GO:0007606=IBA, GO:0031224=IDA, GO:0048701=IEA, GO:0001894=IEA, GO:0007610=IEA, GO:0006833=TAS, GO:0007565=NAS, GO:0031683=IBA, GO:0031234=IBA, GO:0001958=IEA, GO:0007186=IEA, GO:0071870=ISS, GO:0043588=IEA, GO:0030133=IEA, GO:0005886=IEA, GO:0031852=IBA, GO:0003924=IBA, GO:0044281=TAS, GO:0071380=ISS, GO:0046872=IEA, GO:0030425=IEA, GO:0005829=ISS, GO:0007191=IBA, GO:0007190=TAS, GO:0003674=ND, GO:0005737=IDA, GO:0035264=IEA, GO:0071377=TAS, GO:0071514=IEA, GO:0006171=TAS, GO:0004871=IBA, GO:0042493=IEA, GO:0005834=IBA, GO:0045672=IEA, GO:0046907=NAS, GO:0005576=NAS, GO:0005525=IEA, GO:0055085=TAS, GO:0001726=IEA, GO:0032588=IDA, GO:0006306=IEA, GO:0040032=IEA, GO:0045669=IEA, GO:0019001=IEA, GO:0006112=IEA, GO:0004016=TAS, GO:0016020=ISS, GO:0035255=IBA, GO:0050796=TAS, GO:0007596=TAS, GO:0035116=IEA} DNA methylation, G-protein coupled receptor signaling pathway, activation of adenylate cyclase activity, adenylate cyclase-activating dopamine receptor signaling pathway, behavior, blood coagulation, cAMP biosynthetic process, cartilage development, cellular response to catecholamine stimulus, cellular response to glucagon stimulus, cellular response to prostaglandin E stimulus, embryonic cranial skeleton morphogenesis, embryonic hindlimb morphogenesis, endochondral ossification, energy reserve metabolic process, female pregnancy, genetic imprinting, intracellular transport, multicellular organism growth, positive regulation of osteoblast differentiation, positive regulation of osteoclast differentiation, post-embryonic body morphogenesis, protein secretion, regulation of insulin secretion, response to drug, sensory perception of chemical stimulus, sensory perception of smell, skin development, small molecule metabolic process, tissue homeostasis, transmembrane transport, water transport cytoplasm, cytosol, dendrite, extracellular region, extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, intrinsic to membrane, membrane, plasma membrane, ruffle, trans-Golgi network membrane, transport vesicle G-protein beta/gamma-subunit complex binding, GTP binding, GTPase activity, adenylate cyclase activity, guanyl nucleotide binding, ionotropic glutamate receptor binding, metal ion binding, molecular_function, mu-type opioid receptor binding, signal transducer activity Human UniProtKB:P63095 GNAT1 Reactome UniProtKB {GO:0000035=GO_REF:0000024, GO:0005886=Reactome:REACT_18400, GO:0007603=PMID:17584859, GO:0060041=GO_REF:0000019, GO:0042622=GO_REF:0000024, GO:0008283=GO_REF:0000019, GO:0003924=PMID:17584859, GO:0009642=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0016324=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0071257=GO_REF:0000019, GO:0050908=PMID:17584859, GO:0043025=GO_REF:0000019, GO:0009416=GO_REF:0000024, GO:0004871=GO_REF:0000033, GO:0001580=GO_REF:0000033, GO:0016056=GO_REF:0000019, GO:0001664=GO_REF:0000033, GO:0019901=GO_REF:0000024, GO:0051343=GO_REF:0000019, GO:0051344=GO_REF:0000024, GO:0005834=GO_REF:0000033, GO:0031683=GO_REF:0000033, GO:0005525=GO_REF:0000024, GO:0050917=GO_REF:0000033, GO:0031234=GO_REF:0000033, GO:0007165=PMID:8673138, GO:0001917=PMID:2534964, GO:0016020=PMID:7822269, GO:0032391=GO_REF:0000019, GO:0007188=GO_REF:0000033, GO:0019003=GO_REF:0000024, GO:0007601=PMID:8673138, GO:0042462=GO_REF:0000019, GO:0001750=PMID:2534964} P11488 Guanine nucleotide-binding protein G(t) subunit alpha-1 protein 20130213 {GO:0000035=ISS, GO:0005886=TAS, GO:0007603=IMP, GO:0060041=IEA, GO:0042622=ISS, GO:0008283=IEA, GO:0003924=NAS, GO:0009642=IEA, GO:0046872=IEA, GO:0016324=IEA, GO:0005737=IEA, GO:0071257=IEA, GO:0050908=IMP, GO:0043025=IEA, GO:0009416=ISS, GO:0004871=IBA, GO:0001580=IBA, GO:0016056=IEA, GO:0001664=IBA, GO:0019901=ISS, GO:0051343=IEA, GO:0051344=ISS, GO:0005834=IBA, GO:0031683=IBA, GO:0005525=ISS, GO:0050917=IBA, GO:0031234=IBA, GO:0007165=NAS, GO:0001917=IDA, GO:0016020=NAS, GO:0032391=IEA, GO:0007188=IBA, GO:0019003=ISS, GO:0007601=TAS, GO:0042462=IEA, GO:0001750=IDA} adenylate cyclase-modulating G-protein coupled receptor signaling pathway, cell proliferation, cellular response to electrical stimulus, detection of chemical stimulus involved in sensory perception of bitter taste, detection of light stimulus involved in visual perception, eye photoreceptor cell development, negative regulation of cyclic-nucleotide phosphodiesterase activity, phototransduction, visible light, positive regulation of cyclic-nucleotide phosphodiesterase activity, response to light intensity, response to light stimulus, retina development in camera-type eye, rhodopsin mediated signaling pathway, sensory perception of umami taste, signal transduction, visual perception apical plasma membrane, cytoplasm, extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, membrane, neuronal cell body, photoreceptor connecting cilium, photoreceptor inner segment, photoreceptor outer segment, photoreceptor outer segment membrane, plasma membrane G-protein beta/gamma-subunit complex binding, G-protein coupled receptor binding, GDP binding, GTP binding, GTPase activity, acyl binding, metal ion binding, protein kinase binding, signal transducer activity Human GNAT2 Reactome UniProtKB {GO:0001664=GO_REF:0000033, GO:0005886=Reactome:REACT_18400, GO:0046549=GO_REF:0000019, GO:0042622=GO_REF:0000024, GO:0005834=GO_REF:0000033, GO:0003924=GO_REF:0000033, GO:0031683=GO_REF:0000033, GO:0009642=GO_REF:0000019, GO:0005525=PMID:1936270, GO:0007204=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0008020=PMID:2534964, GO:0031234=GO_REF:0000033, GO:0001917=PMID:2534964, GO:0007186=PMID:2534964, GO:0050908=PMID:12077706, GO:0007188=GO_REF:0000033, GO:0004871=GO_REF:0000033, GO:0007602=PMID:2534964, GO:0007601=PMID:2534964, GO:0001580=GO_REF:0000033, GO:0001750=GO_REF:0000024} P19087 Guanine nucleotide-binding protein G(t) subunit alpha-2 protein 20130213 {GO:0001664=IBA, GO:0005886=TAS, GO:0046549=IEA, GO:0042622=ISS, GO:0005834=IBA, GO:0003924=IBA, GO:0031683=IBA, GO:0009642=IEA, GO:0005525=NAS, GO:0007204=IEA, GO:0046872=IEA, GO:0008020=NAS, GO:0031234=IBA, GO:0001917=IDA, GO:0007186=NAS, GO:0050908=IMP, GO:0007188=IBA, GO:0004871=IBA, GO:0007602=NAS, GO:0007601=NAS, GO:0001580=IBA, GO:0001750=ISS} G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, detection of chemical stimulus involved in sensory perception of bitter taste, detection of light stimulus involved in visual perception, elevation of cytosolic calcium ion concentration, phototransduction, response to light intensity, retinal cone cell development, visual perception extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, photoreceptor inner segment, photoreceptor outer segment, photoreceptor outer segment membrane, plasma membrane G-protein beta/gamma-subunit complex binding, G-protein coupled photoreceptor activity, G-protein coupled receptor binding, GTP binding, GTPase activity, metal ion binding, signal transducer activity Human GNAT3 Reactome UniProtKB {GO:0001664=GO_REF:0000033, GO:0005886=Reactome:REACT_15549, GO:0005834=GO_REF:0000033, GO:0003924=GO_REF:0000033, GO:0031683=GO_REF:0000033, GO:0005525=GO_REF:0000019, GO:0050916=GO_REF:0000033, GO:0050917=GO_REF:0000033, GO:0046872=GO_REF:0000037, GO:0031234=GO_REF:0000033, GO:0043234=PMID:18468998, GO:0001917=GO_REF:0000033, GO:0016324=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0007188=GO_REF:0000033, GO:0004871=GO_REF:0000033, GO:0001580=GO_REF:0000033, GO:0035094=GO_REF:0000019, GO:0001750=GO_REF:0000033} A8MTJ3 Guanine nucleotide-binding protein G(t) subunit alpha-3 protein 20081107 {GO:0001664=IBA, GO:0005886=TAS, GO:0005834=IBA, GO:0003924=IBA, GO:0031683=IBA, GO:0005525=IEA, GO:0050916=IBA, GO:0050917=IBA, GO:0046872=IEA, GO:0031234=IBA, GO:0043234=IDA, GO:0001917=IBA, GO:0016324=IEA, GO:0005737=IEA, GO:0007188=IBA, GO:0004871=IBA, GO:0001580=IBA, GO:0035094=IEA, GO:0001750=IBA} adenylate cyclase-modulating G-protein coupled receptor signaling pathway, detection of chemical stimulus involved in sensory perception of bitter taste, response to nicotine, sensory perception of sweet taste, sensory perception of umami taste apical plasma membrane, cytoplasm, extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, photoreceptor inner segment, photoreceptor outer segment, plasma membrane, protein complex G-protein beta/gamma-subunit complex binding, G-protein coupled receptor binding, GTP binding, GTPase activity, metal ion binding, signal transducer activity Human GNAZ Reactome UniProtKB {GO:0005886=Reactome:REACT_22380, GO:0005783=PMID:2117645, GO:0005834=GO_REF:0000033, GO:0003924=GO_REF:0000033, GO:0005635=PMID:2117645, GO:0005525=GO_REF:0000037, GO:0031683=GO_REF:0000033, GO:0007193=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=GO_REF:0000019, GO:0031234=GO_REF:0000033, GO:0007186=PMID:3129724, GO:0007188=GO_REF:0000033, GO:0031821=GO_REF:0000033, GO:0004871=GO_REF:0000033, GO:0005057=PMID:2456569} P19086 Guanine nucleotide-binding protein G(z) subunit alpha protein 20130213 {GO:0005886=TAS, GO:0005783=TAS, GO:0005834=IBA, GO:0003924=IBA, GO:0005635=TAS, GO:0005525=IEA, GO:0031683=IBA, GO:0007193=IEA, GO:0046872=IEA, GO:0005829=IEA, GO:0031234=IBA, GO:0007186=TAS, GO:0007188=IBA, GO:0031821=IBA, GO:0004871=IBA, GO:0005057=TAS} G-protein coupled receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway cytosol, endoplasmic reticulum, extrinsic to internal side of plasma membrane, heterotrimeric G-protein complex, nuclear envelope, plasma membrane G-protein beta/gamma-subunit complex binding, G-protein coupled serotonin receptor binding, GTP binding, GTPase activity, metal ion binding, receptor signaling protein activity, signal transducer activity Human GNB1 GOC UniProtKB {GO:0060041=GO_REF:0000019, GO:0005886=Reactome:REACT_25066, GO:0042622=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:0003924=PMID:1543505, GO:0007200=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0007265=PMID:8717044, GO:0044281=Reactome:REACT_111217, GO:0071380=GO_REF:0000024, GO:0007204=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0007191=GO_REF:0000024, GO:0005622=GO_REF:0000024, GO:0050909=GO_REF:0000019, GO:0071377=Reactome:REACT_1665, GO:0004871=GO_REF:0000037, GO:0005834=PMID:1543505, GO:0071456=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0007213=PMID:8717044, GO:0044297=GO_REF:0000019, GO:0006184=PMID:3095147, GO:0001917=GO_REF:0000019, GO:0007165=PMID:8717044, GO:0051020=PMID:19255495, GO:0006112=Reactome:REACT_1505, GO:0016020=GO_REF:0000024, GO:0007596=Reactome:REACT_604, GO:0071870=GO_REF:0000024, GO:0010659=GO_REF:0000019} P62873 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 protein 20130413 {GO:0060041=IEA, GO:0005886=TAS, GO:0042622=IEA, GO:0008283=IEA, GO:0003924=IDA, GO:0007200=IEA, GO:0007268=TAS, GO:0007265=TAS, GO:0044281=TAS, GO:0071380=ISS, GO:0007204=IEA, GO:0030425=IEA, GO:0007191=ISS, GO:0005622=ISS, GO:0050909=IEA, GO:0071377=TAS, GO:0004871=IEA, GO:0005834=IDA, GO:0071456=IEA, GO:0030168=TAS, GO:0007213=TAS, GO:0044297=IEA, GO:0006184=TAS, GO:0001917=IEA, GO:0007165=TAS, GO:0051020=IPI, GO:0006112=TAS, GO:0016020=ISS, GO:0007596=TAS, GO:0071870=ISS, GO:0010659=IEA} G-protein coupled acetylcholine receptor signaling pathway, GTP catabolic process, Ras protein signal transduction, adenylate cyclase-activating dopamine receptor signaling pathway, blood coagulation, cardiac muscle cell apoptotic process, cell proliferation, cellular response to catecholamine stimulus, cellular response to glucagon stimulus, cellular response to hypoxia, cellular response to prostaglandin E stimulus, elevation of cytosolic calcium ion concentration, energy reserve metabolic process, phospholipase C-activating G-protein coupled receptor signaling pathway, platelet activation, retina development in camera-type eye, sensory perception of taste, signal transduction, small molecule metabolic process, synaptic transmission cell body, dendrite, heterotrimeric G-protein complex, intracellular, membrane, photoreceptor inner segment, photoreceptor outer segment membrane, plasma membrane GTPase activity, GTPase binding, signal transducer activity Human GNB1L UniProtKB UniProtKB {GO:0035556=PMID:11072084, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000019, GO:0007186=PMID:11072084, GO:0035176=GO_REF:0000019, GO:0009898=PMID:11072084} Q9BYB4 Guanine nucleotide-binding protein subunit beta-like protein 1 protein 20030805 {GO:0035556=NAS, GO:0003674=ND, GO:0005737=IEA, GO:0007186=NAS, GO:0035176=IEA, GO:0009898=NAS} G-protein coupled receptor signaling pathway, intracellular signal transduction, social behavior cytoplasm, internal side of plasma membrane molecular_function Human GNB2 GOC UniProtKB {GO:0005515=PMID:16498633, GO:0048471=PMID:16498633, GO:0005886=Reactome:REACT_25066, GO:0005246=GO_REF:0000019, GO:0003924=PMID:2902634, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0044297=GO_REF:0000019, GO:0006184=PMID:2902634, GO:0043234=GO_REF:0000019, GO:0051020=PMID:19255495, GO:0006112=Reactome:REACT_1505, GO:0007186=PMID:7649993, GO:0071377=Reactome:REACT_1665, GO:0004871=GO_REF:0000037} P62879 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 protein 20130413 {GO:0005515=IPI, GO:0048471=IDA, GO:0005886=TAS, GO:0005246=IEA, GO:0003924=TAS, GO:0007268=TAS, GO:0044281=TAS, GO:0044297=IEA, GO:0006184=TAS, GO:0043234=IEA, GO:0051020=IPI, GO:0006112=TAS, GO:0007186=TAS, GO:0071377=TAS, GO:0004871=IEA} G-protein coupled receptor signaling pathway, GTP catabolic process, cellular response to glucagon stimulus, energy reserve metabolic process, small molecule metabolic process, synaptic transmission cell body, perinuclear region of cytoplasm, plasma membrane, protein complex GTPase activity, GTPase binding, calcium channel regulator activity, protein binding, signal transducer activity Human GNB2L1 GOC UniProtKB {GO:0017148=GO_REF:0000024, GO:0005515=PMID:21146485, GO:0030308=PMID:9584165, GO:0048471=PMID:11279199, GO:0007369=GO_REF:0000037, GO:0061099=PMID:9584165, GO:0030178=GO_REF:0000024, GO:0032436=PMID:19785988, GO:0015935=GO_REF:0000024, GO:0005634=PMID:17108144, GO:0030425=GO_REF:0000024, GO:0032880=GO_REF:0000024, GO:0050765=PMID:21347310, GO:0005737=PMID:19785988, GO:0005080=PMID:11279199, GO:0043025=GO_REF:0000024, GO:0051726=PMID:9584165, GO:0043204=GO_REF:0000039, GO:0005856=GO_REF:0000039, GO:0008200=GO_REF:0000024, GO:0042169=PMID:11279199, GO:0032464=PMID:20541605, GO:0030971=PMID:9584165, GO:0030335=PMID:20499158, GO:0043065=PMID:20541605, GO:0019903=PMID:11278757, GO:2000543=GO_REF:0000024, GO:2000114=GO_REF:0000024, GO:0005102=PMID:12809483, GO:0030292=PMID:9584165, GO:0030496=PMID:15166316, GO:0001891=PMID:21347310, GO:0043547=PMID:20499158, GO:0007049=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0001934=PMID:17108144, GO:0048511=GO_REF:0000037, GO:0051302=GO_REF:0000024, GO:0090003=GO_REF:0000019} P63244 Guanine nucleotide-binding protein subunit beta-2-like 1 protein 20130413 {GO:0017148=ISS, GO:0005515=IPI, GO:0030308=IDA, GO:0048471=IDA, GO:0007369=IEA, GO:0061099=IDA, GO:0030178=ISS, GO:0032436=IDA, GO:0015935=ISS, GO:0005634=IDA, GO:0030425=ISS, GO:0032880=ISS, GO:0050765=IMP, GO:0005737=IDA, GO:0005080=IDA, GO:0043025=ISS, GO:0051726=IDA, GO:0043204=IEA, GO:0005856=IEA, GO:0008200=ISS, GO:0042169=IDA, GO:0032464=IDA, GO:0030971=IDA, GO:0030335=IDA, GO:0043065=IDA, GO:0019903=IPI, GO:2000543=ISS, GO:2000114=ISS, GO:0005102=NAS, GO:0030292=IDA, GO:0030496=IDA, GO:0001891=IDA, GO:0043547=IDA, GO:0007049=IEA, GO:0019048=IEA, GO:0001934=IDA, GO:0048511=IEA, GO:0051302=ISS, GO:0090003=IEA} cell cycle, gastrulation, negative regulation of Wnt receptor signaling pathway, negative regulation of cell growth, negative regulation of phagocytosis, negative regulation of protein tyrosine kinase activity, negative regulation of translation, positive regulation of GTPase activity, positive regulation of apoptotic process, positive regulation of cell migration, positive regulation of gastrulation, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of protein homooligomerization, positive regulation of protein phosphorylation, regulation of cell cycle, regulation of cell division, regulation of establishment of cell polarity, regulation of establishment of protein localization to plasma membrane, regulation of protein localization, rhythmic process, virus-host interaction cytoplasm, cytoskeleton, dendrite, midbody, neuronal cell body, nucleus, perikaryon, perinuclear region of cytoplasm, phagocytic cup, small ribosomal subunit SH2 domain binding, ion channel inhibitor activity, protein binding, protein kinase C binding, protein phosphatase binding, protein tyrosine kinase inhibitor activity, receptor binding, receptor tyrosine kinase binding Human GNB3 GOC UniProtKB {GO:0043005=GO_REF:0000019, GO:0005886=Reactome:REACT_25066, GO:0003924=PMID:9425898, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0044297=GO_REF:0000019, GO:0006184=PMID:9425898, GO:0051020=PMID:19255495, GO:0006112=Reactome:REACT_1505, GO:0007186=PMID:2107550, GO:0071377=Reactome:REACT_1665, GO:0008217=PMID:9425898, GO:0004871=GO_REF:0000037} P16520 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 protein 20130413 {GO:0043005=IEA, GO:0005886=TAS, GO:0003924=TAS, GO:0007268=TAS, GO:0044281=TAS, GO:0044297=IEA, GO:0006184=TAS, GO:0051020=IPI, GO:0006112=TAS, GO:0007186=TAS, GO:0071377=TAS, GO:0008217=TAS, GO:0004871=IEA} G-protein coupled receptor signaling pathway, GTP catabolic process, cellular response to glucagon stimulus, energy reserve metabolic process, regulation of blood pressure, small molecule metabolic process, synaptic transmission cell body, neuron projection, plasma membrane GTPase activity, GTPase binding, signal transducer activity Human GNB4 Reactome UniProtKB {GO:0006112=Reactome:REACT_1505, GO:0005886=Reactome:REACT_22110, GO:0071377=Reactome:REACT_1665, GO:0044281=Reactome:REACT_111217, GO:0004871=GO_REF:0000037} Q9HAV0 Guanine nucleotide-binding protein subunit beta-4 protein 20130301 {GO:0006112=TAS, GO:0005886=TAS, GO:0071377=TAS, GO:0044281=TAS, GO:0004871=IEA} cellular response to glucagon stimulus, energy reserve metabolic process, small molecule metabolic process plasma membrane signal transducer activity Human GNB5 GOC UniProtKB {GO:0006184=PMID:9606987, GO:0007165=PMID:9606987, GO:0007186=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0005834=GO_REF:0000029, GO:0003924=PMID:9606987, GO:0005634=GO_REF:0000019, GO:0004871=PMID:9606987} O14775 Guanine nucleotide-binding protein subunit beta-5 protein 20130413 {GO:0006184=NAS, GO:0007165=NAS, GO:0007186=IEA, GO:0005886=IEA, GO:0005834=NAS, GO:0003924=NAS, GO:0005634=IEA, GO:0004871=NAS} G-protein coupled receptor signaling pathway, GTP catabolic process, signal transduction heterotrimeric G-protein complex, nucleus, plasma membrane GTPase activity, signal transducer activity Human GNE PINC UniProtKB {GO:0008761=GO_REF:0000002, GO:0006054=PMID:9305888, GO:0006045=GO_REF:0000041, GO:0006047=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0005829=GO_REF:0000019, GO:0005737=PMID:9305888, GO:0046380=GO_REF:0000002, GO:0016787=GO_REF:0000037, GO:0009384=GO_REF:0000003, GO:0007155=PMID:10334995, GO:0009103=GO_REF:0000002} Q9Y223 Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase protein 20030904 {GO:0008761=IEA, GO:0006054=TAS, GO:0006045=IEA, GO:0006047=IEA, GO:0005524=IEA, GO:0046872=IEA, GO:0005829=IEA, GO:0005737=TAS, GO:0046380=IEA, GO:0016787=IEA, GO:0009384=IEA, GO:0007155=TAS, GO:0009103=IEA} N-acetylglucosamine biosynthetic process, N-acetylneuraminate biosynthetic process, N-acetylneuraminate metabolic process, UDP-N-acetylglucosamine metabolic process, cell adhesion, lipopolysaccharide biosynthetic process cytoplasm, cytosol ATP binding, N-acylmannosamine kinase activity, UDP-N-acetylglucosamine 2-epimerase activity, hydrolase activity, metal ion binding Human GNG10 GOC UniProtKB {GO:0006184=PMID:7665596, GO:0007165=PMID:7665596, GO:0006112=Reactome:REACT_1505, GO:0005886=Reactome:REACT_25066, GO:0007186=GO_REF:0000002, GO:0071377=Reactome:REACT_1665, GO:0005834=GO_REF:0000002, GO:0003924=PMID:7665596, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0004871=GO_REF:0000037} P50151 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 protein 20130413 {GO:0006184=TAS, GO:0007165=TAS, GO:0006112=TAS, GO:0005886=TAS, GO:0007186=IEA, GO:0071377=TAS, GO:0005834=IEA, GO:0003924=TAS, GO:0007268=TAS, GO:0044281=TAS, GO:0004871=IEA} G-protein coupled receptor signaling pathway, GTP catabolic process, cellular response to glucagon stimulus, energy reserve metabolic process, signal transduction, small molecule metabolic process, synaptic transmission heterotrimeric G-protein complex, plasma membrane GTPase activity, signal transducer activity Human GNG11 GOC UniProtKB {GO:0006184=PMID:7665596, GO:0007165=PMID:7665596, GO:0006112=Reactome:REACT_1505, GO:0005886=Reactome:REACT_22110, GO:0007186=GO_REF:0000002, GO:0071377=Reactome:REACT_1665, GO:0005834=GO_REF:0000002, GO:0003924=PMID:7665596, GO:0044281=Reactome:REACT_111217, GO:0004871=GO_REF:0000037} P61952 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 protein 20130413 {GO:0006184=TAS, GO:0007165=TAS, GO:0006112=TAS, GO:0005886=TAS, GO:0007186=IEA, GO:0071377=TAS, GO:0005834=IEA, GO:0003924=TAS, GO:0044281=TAS, GO:0004871=IEA} G-protein coupled receptor signaling pathway, GTP catabolic process, cellular response to glucagon stimulus, energy reserve metabolic process, signal transduction, small molecule metabolic process heterotrimeric G-protein complex, plasma membrane GTPase activity, signal transducer activity Human GNG12 Reactome UniProtKB {GO:0007165=PMID:10819326, GO:0006112=Reactome:REACT_1505, GO:0005886=Reactome:REACT_25066, GO:0007186=GO_REF:0000002, GO:0071377=Reactome:REACT_1665, GO:0005834=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0004871=GO_REF:0000037} Q9UBI6 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 protein 20130301 {GO:0007165=TAS, GO:0006112=TAS, GO:0005886=TAS, GO:0007186=IEA, GO:0071377=TAS, GO:0005834=IEA, GO:0007268=TAS, GO:0044281=TAS, GO:0004871=IEA} G-protein coupled receptor signaling pathway, cellular response to glucagon stimulus, energy reserve metabolic process, signal transduction, small molecule metabolic process, synaptic transmission heterotrimeric G-protein complex, plasma membrane signal transducer activity Human GNG13 Reactome UniProtKB {GO:0006112=Reactome:REACT_1505, GO:0005886=Reactome:REACT_22110, GO:0050909=GO_REF:0000019, GO:0071377=Reactome:REACT_1665, GO:0005834=GO_REF:0000019, GO:0007200=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0004871=GO_REF:0000037} Q9P2W3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 protein 20130301 {GO:0006112=TAS, GO:0005886=TAS, GO:0050909=IEA, GO:0071377=TAS, GO:0005834=IEA, GO:0007200=IEA, GO:0044281=TAS, GO:0004871=IEA} cellular response to glucagon stimulus, energy reserve metabolic process, phospholipase C-activating G-protein coupled receptor signaling pathway, sensory perception of taste, small molecule metabolic process heterotrimeric G-protein complex, plasma membrane signal transducer activity Human GNG2 BHF-UCL UniProtKB {GO:0005886=Reactome:REACT_25066, GO:0008283=GO_REF:0000019, GO:0005834=GO_REF:0000024, GO:0007268=Reactome:REACT_13685, GO:0030168=Reactome:REACT_798, GO:0044281=Reactome:REACT_111217, GO:0071380=GO_REF:0000024, GO:0007191=GO_REF:0000024, GO:0006112=Reactome:REACT_1505, GO:0016020=GO_REF:0000024, GO:0007186=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0071377=Reactome:REACT_1665, GO:0071870=GO_REF:0000024, GO:0004871=GO_REF:0000037} P59768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 protein 20120329 {GO:0005886=TAS, GO:0008283=IEA, GO:0005834=ISS, GO:0007268=TAS, GO:0030168=TAS, GO:0044281=TAS, GO:0071380=ISS, GO:0007191=ISS, GO:0006112=TAS, GO:0016020=ISS, GO:0007186=IEA, GO:0007596=TAS, GO:0071377=TAS, GO:0071870=ISS, GO:0004871=IEA} G-protein coupled receptor signaling pathway, adenylate cyclase-activating dopamine receptor signaling pathway, blood coagulation, cell proliferation, cellular response to catecholamine stimulus, cellular response to glucagon stimulus, cellular response to prostaglandin E stimulus, energy reserve metabolic process, platelet activation, small molecule metabolic process, synaptic transmission heterotrimeric G-protein complex, membrane, plasma membrane signal transducer activity Human UniProtKB:P63212 GNG3 GOC UniProtKB {GO:0006184=PMID:10075696, GO:0000187=PMID:10075696, GO:0006112=Reactome:REACT_1505, GO:0005886=Reactome:REACT_25066, GO:0007186=GO_REF:0000002, GO:0071377=Reactome:REACT_1665, GO:0005834=GO_REF:0000002, GO:0003924=PMID:10075696, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0004871=GO_REF:0000037} P63215 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 protein 20130413 {GO:0006184=TAS, GO:0000187=TAS, GO:0006112=TAS, GO:0005886=TAS, GO:0007186=IEA, GO:0071377=TAS, GO:0005834=IEA, GO:0003924=TAS, GO:0007268=TAS, GO:0044281=TAS, GO:0004871=IEA} G-protein coupled receptor signaling pathway, GTP catabolic process, activation of MAPK activity, cellular response to glucagon stimulus, energy reserve metabolic process, small molecule metabolic process, synaptic transmission heterotrimeric G-protein complex, plasma membrane GTPase activity, signal transducer activity Human GNG4 IntAct UniProtKB {GO:0005515=PMID:23021213, GO:0030308=PMID:15824735, GO:0006112=Reactome:REACT_1505, GO:0008277=PMID:7665596, GO:0005886=Reactome:REACT_25066, GO:0007186=GO_REF:0000002, GO:0071377=Reactome:REACT_1665, GO:0005834=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0004871=GO_REF:0000037} P50150 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 protein 20130415 {GO:0005515=IPI, GO:0030308=IMP, GO:0006112=TAS, GO:0008277=TAS, GO:0005886=TAS, GO:0007186=IEA, GO:0071377=TAS, GO:0005834=IEA, GO:0007268=TAS, GO:0044281=TAS, GO:0004871=IEA} G-protein coupled receptor signaling pathway, cellular response to glucagon stimulus, energy reserve metabolic process, negative regulation of cell growth, regulation of G-protein coupled receptor protein signaling pathway, small molecule metabolic process, synaptic transmission heterotrimeric G-protein complex, plasma membrane protein binding, signal transducer activity Human UniProtKB:Q3MMY3 GNG5 GOC UniProtKB {GO:0006184=PMID:10819326, GO:0007165=PMID:9790912, GO:0006112=Reactome:REACT_1505, GO:0005886=Reactome:REACT_25066, GO:0007186=PMID:20277477, GO:0071377=Reactome:REACT_1665, GO:0005834=PMID:9790912, GO:0003924=PMID:10819326, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0004871=PMID:20277477} P63218 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 protein 20130413 {GO:0006184=NAS, GO:0007165=NAS, GO:0006112=TAS, GO:0005886=TAS, GO:0007186=NAS, GO:0071377=TAS, GO:0005834=NAS, GO:0003924=NAS, GO:0007268=TAS, GO:0044281=TAS, GO:0004871=NAS} G-protein coupled receptor signaling pathway, GTP catabolic process, cellular response to glucagon stimulus, energy reserve metabolic process, signal transduction, small molecule metabolic process, synaptic transmission heterotrimeric G-protein complex, plasma membrane GTPase activity, signal transducer activity Human GNG7 Reactome UniProtKB {GO:0005886=Reactome:REACT_25066, GO:0005834=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0008277=PMID:9600093, GO:0006112=Reactome:REACT_1505, GO:0007186=GO_REF:0000002, GO:0071377=Reactome:REACT_1665, GO:0001662=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0004871=GO_REF:0000019, GO:0045761=GO_REF:0000019, GO:0007168=GO_REF:0000019} O60262 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 protein 20130301 {GO:0005886=TAS, GO:0005834=IEA, GO:0007268=TAS, GO:0044281=TAS, GO:0008277=TAS, GO:0006112=TAS, GO:0007186=IEA, GO:0071377=TAS, GO:0001662=IEA, GO:0007626=IEA, GO:0004871=IEA, GO:0045761=IEA, GO:0007168=IEA} G-protein coupled receptor signaling pathway, behavioral fear response, cellular response to glucagon stimulus, energy reserve metabolic process, locomotory behavior, receptor guanylyl cyclase signaling pathway, regulation of G-protein coupled receptor protein signaling pathway, regulation of adenylate cyclase activity, small molecule metabolic process, synaptic transmission heterotrimeric G-protein complex, plasma membrane signal transducer activity Human GNG8 GOC UniProtKB {GO:0006184=PMID:10819326, GO:0006112=Reactome:REACT_1505, GO:0005886=Reactome:REACT_25066, GO:0007186=PMID:10819326, GO:0071377=Reactome:REACT_1665, GO:0005834=GO_REF:0000002, GO:0003924=PMID:10819326, GO:0007268=Reactome:REACT_13685, GO:0005576=GO_REF:0000029, GO:0044281=Reactome:REACT_111217, GO:0004871=PMID:10819326, GO:0007399=GO_REF:0000019} Q9UK08 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 protein 20130413 {GO:0006184=NAS, GO:0006112=TAS, GO:0005886=TAS, GO:0007186=NAS, GO:0071377=TAS, GO:0005834=IEA, GO:0003924=NAS, GO:0007268=TAS, GO:0005576=NAS, GO:0044281=TAS, GO:0004871=NAS, GO:0007399=IEA} G-protein coupled receptor signaling pathway, GTP catabolic process, cellular response to glucagon stimulus, energy reserve metabolic process, nervous system development, small molecule metabolic process, synaptic transmission extracellular region, heterotrimeric G-protein complex, plasma membrane GTPase activity, signal transducer activity Human GNGT1 GOC UniProtKB {GO:0005886=Reactome:REACT_25066, GO:0005834=GO_REF:0000019, GO:0003924=PMID:8661128, GO:0007268=Reactome:REACT_13685, GO:0071456=GO_REF:0000019, GO:0006184=PMID:8661128, GO:0001917=GO_REF:0000019, GO:0007165=PMID:8661128, GO:0008104=GO_REF:0000019, GO:0007186=GO_REF:0000002, GO:0010659=GO_REF:0000019, GO:0004871=GO_REF:0000037, GO:0007602=GO_REF:0000019, GO:0042462=GO_REF:0000019, GO:0001750=GO_REF:0000019} P63211 Guanine nucleotide-binding protein G(T) subunit gamma-T1 protein 20130413 {GO:0005886=TAS, GO:0005834=IEA, GO:0003924=TAS, GO:0007268=TAS, GO:0071456=IEA, GO:0006184=TAS, GO:0001917=IEA, GO:0007165=NAS, GO:0008104=IEA, GO:0007186=IEA, GO:0010659=IEA, GO:0004871=IEA, GO:0007602=IEA, GO:0042462=IEA, GO:0001750=IEA} G-protein coupled receptor signaling pathway, GTP catabolic process, cardiac muscle cell apoptotic process, cellular response to hypoxia, eye photoreceptor cell development, phototransduction, protein localization, signal transduction, synaptic transmission heterotrimeric G-protein complex, photoreceptor inner segment, photoreceptor outer segment, plasma membrane GTPase activity, signal transducer activity Human GNGT2 GOC UniProtKB {GO:0006184=PMID:9286705, GO:0005886=Reactome:REACT_25066, GO:0007186=PMID:9286705, GO:0005834=PMID:10570481, GO:0003924=PMID:10570481, GO:0007268=Reactome:REACT_13685, GO:0005576=GO_REF:0000029, GO:0004871=PMID:9286705, GO:0007602=PMID:9286705} O14610 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 protein 20130413 {GO:0006184=NAS, GO:0005886=TAS, GO:0007186=NAS, GO:0005834=IDA, GO:0003924=IDA, GO:0007268=TAS, GO:0005576=NAS, GO:0004871=NAS, GO:0007602=NAS} G-protein coupled receptor signaling pathway, GTP catabolic process, phototransduction, synaptic transmission extracellular region, heterotrimeric G-protein complex, plasma membrane GTPase activity, signal transducer activity Human GNL1 GOC UniProtKB {GO:0006184=GO_REF:0000033, GO:0007165=PMID:8180467, GO:0005198=PMID:8180467, GO:0042254=GO_REF:0000033, GO:0003924=GO_REF:0000033, GO:0005525=PMID:8180467, GO:0005615=PMID:8180467, GO:0002456=PMID:8180467, GO:0006974=PMID:17525332, GO:0005829=GO_REF:0000033} P36915 Guanine nucleotide-binding protein-like 1 protein 20130413 {GO:0006184=IBA, GO:0007165=NAS, GO:0005198=NAS, GO:0042254=IBA, GO:0003924=IBA, GO:0005525=NAS, GO:0005615=NAS, GO:0002456=NAS, GO:0006974=IDA, GO:0005829=IBA} GTP catabolic process, T cell mediated immunity, response to DNA damage stimulus, ribosome biogenesis, signal transduction cytosol, extracellular space GTP binding, GTPase activity, structural molecule activity Human PANTHER:PTN000119716 GNL2 GOC UniProtKB {GO:0006184=PMID:8822211, GO:0008150=GO_REF:0000015, GO:0042254=GO_REF:0000033, GO:0003924=GO_REF:0000033, GO:0005730=GO_REF:0000052, GO:0005634=PMID:8822211, GO:0005525=PMID:8822211} Q13823 Nucleolar GTP-binding protein 2 protein 20130413 {GO:0006184=NAS, GO:0008150=ND, GO:0042254=IBA, GO:0003924=IBA, GO:0005730=IDA, GO:0005634=TAS, GO:0005525=NAS} GTP catabolic process, biological_process, ribosome biogenesis nucleolus, nucleus GTP binding, GTPase activity Human GNL3 GOC UniProtKB {GO:0006184=GO_REF:0000033, GO:0005515=PMID:21988832, GO:0008283=GO_REF:0000019, GO:0042254=GO_REF:0000033, GO:0042127=GO_REF:0000024, GO:0003924=GO_REF:0000033, GO:0005730=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0005654=GO_REF:0000019, GO:0005525=GO_REF:0000024} Q9BVP2 Guanine nucleotide-binding protein-like 3 protein 20130413 {GO:0006184=IBA, GO:0005515=IPI, GO:0008283=IEA, GO:0042254=IBA, GO:0042127=ISS, GO:0003924=IBA, GO:0005730=ISS, GO:0005634=ISS, GO:0005654=IEA, GO:0005525=ISS} GTP catabolic process, cell proliferation, regulation of cell proliferation, ribosome biogenesis nucleolus, nucleoplasm, nucleus GTP binding, GTPase activity, protein binding Human PANTHER:PTN000119716 GNL3L GOC UniProtKB {GO:0006184=GO_REF:0000033, GO:0005739=GO_REF:0000052, GO:0005515=PMID:21132010, GO:0042254=GO_REF:0000033, GO:0005730=GO_REF:0000052, GO:0003924=GO_REF:0000033, GO:0005634=GO_REF:0000052, GO:0005525=GO_REF:0000037} Q9NVN8 Guanine nucleotide-binding protein-like 3-like protein protein 20130413 {GO:0006184=IBA, GO:0005739=IDA, GO:0005515=IPI, GO:0042254=IBA, GO:0005730=IDA, GO:0003924=IBA, GO:0005634=IDA, GO:0005525=IEA} GTP catabolic process, ribosome biogenesis mitochondrion, nucleolus, nucleus GTP binding, GTPase activity, protein binding Human PANTHER:PTN000119716 GNLY PINC UniProtKB {GO:0006968=PMID:9756476, GO:0050832=GO_REF:0000037, GO:0031640=GO_REF:0000037, GO:0005615=PMID:2212946, GO:0042742=GO_REF:0000037} P22749 Granulysin protein 20030904 {GO:0006968=TAS, GO:0050832=IEA, GO:0031640=IEA, GO:0005615=TAS, GO:0042742=IEA} cellular defense response, defense response to bacterium, defense response to fungus, killing of cells of other organism extracellular space Human GNMT HPA UniProtKB {GO:0005515=PMID:21988832, GO:0006111=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0005542=GO_REF:0000037, GO:0051289=PMID:15340920, GO:0005977=GO_REF:0000019, GO:0016594=PMID:15340920, GO:0046500=PMID:15340920, GO:0006555=GO_REF:0000019, GO:0006730=GO_REF:0000019, GO:0017174=PMID:15340920, GO:0006464=PMID:10843803} Q14749 Glycine N-methyltransferase protein 20101115 {GO:0005515=IPI, GO:0006111=IEA, GO:0005737=IDA, GO:0005542=IEA, GO:0051289=IPI, GO:0005977=IEA, GO:0016594=IDA, GO:0046500=IDA, GO:0006555=IEA, GO:0006730=IEA, GO:0017174=IDA, GO:0006464=NAS} S-adenosylmethionine metabolic process, cellular protein modification process, glycogen metabolic process, methionine metabolic process, one-carbon metabolic process, protein homotetramerization, regulation of gluconeogenesis cytoplasm folic acid binding, glycine N-methyltransferase activity, glycine binding, protein binding Human GNPAT InterPro UniProtKB {GO:0005782=Reactome:REACT_16930, GO:0030913=GO_REF:0000019, GO:0007584=GO_REF:0000019, GO:0008611=Reactome:REACT_1407, GO:0016290=PMID:8186247, GO:0042493=GO_REF:0000019, GO:0005102=PMID:20178365, GO:0021587=GO_REF:0000019, GO:0004366=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0008654=GO_REF:0000002, GO:0016287=Reactome:REACT_15, GO:0007416=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0042594=GO_REF:0000019, GO:0070542=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0006644=Reactome:REACT_120870, GO:0006654=Reactome:REACT_120906, GO:0044255=Reactome:REACT_16957, GO:0005778=Reactome:REACT_121344, GO:0016044=GO_REF:0000019, GO:0046474=Reactome:REACT_121401, GO:0005777=PMID:15687349} Q5TBH8 Dihydroxyacetone phosphate acyltransferase protein 20130413 {GO:0005782=TAS, GO:0030913=IEA, GO:0007584=IEA, GO:0008611=TAS, GO:0016290=IDA, GO:0042493=IEA, GO:0005102=IPI, GO:0021587=IEA, GO:0004366=IEA, GO:0044281=TAS, GO:0008654=IEA, GO:0016287=TAS, GO:0007416=IEA, GO:0005739=IEA, GO:0042594=IEA, GO:0070542=IEA, GO:0016020=IEA, GO:0006644=TAS, GO:0006654=TAS, GO:0044255=TAS, GO:0005778=TAS, GO:0016044=IEA, GO:0046474=TAS, GO:0005777=IDA} cellular lipid metabolic process, cellular membrane organization, cerebellum morphogenesis, ether lipid biosynthetic process, glycerophospholipid biosynthetic process, paranodal junction assembly, phosphatidic acid biosynthetic process, phospholipid biosynthetic process, phospholipid metabolic process, response to drug, response to fatty acid, response to nutrient, response to starvation, small molecule metabolic process, synapse assembly membrane, mitochondrion, peroxisomal matrix, peroxisomal membrane, peroxisome glycerol-3-phosphate O-acyltransferase activity, glycerone-phosphate O-acyltransferase activity, palmitoyl-CoA hydrolase activity, receptor binding Human InterPro:IPR022284 GNPDA1 PINC UniProtKB {GO:0007338=PMID:9714720, GO:0005737=GO_REF:0000024, GO:0004342=PMID:9438414, GO:0016787=GO_REF:0000037, GO:0005975=GO_REF:0000037, GO:0006043=PMID:9438414, GO:0006044=GO_REF:0000002, GO:0006091=PMID:9438414} P46926 Glucosamine-6-phosphate isomerase 1 protein 20030904 {GO:0007338=TAS, GO:0005737=ISS, GO:0004342=IMP, GO:0016787=IEA, GO:0005975=IEA, GO:0006043=IMP, GO:0006044=IEA, GO:0006091=IMP} N-acetylglucosamine metabolic process, carbohydrate metabolic process, generation of precursor metabolites and energy, glucosamine catabolic process, single fertilization cytoplasm glucosamine-6-phosphate deaminase activity, hydrolase activity Human GNPDA2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0004342=GO_REF:0000003, GO:0016787=GO_REF:0000037, GO:0005975=GO_REF:0000037, GO:0006044=GO_REF:0000002} Q8TDQ7 Glucosamine-6-phosphate isomerase 2 protein 20130413 {GO:0005737=IEA, GO:0004342=IEA, GO:0016787=IEA, GO:0005975=IEA, GO:0006044=IEA} N-acetylglucosamine metabolic process, carbohydrate metabolic process cytoplasm glucosamine-6-phosphate deaminase activity, hydrolase activity Human UniProtKB-SubCell:SL-0086 GNPNAT1 Reactome UniProtKB {GO:0005793=GO_REF:0000019, GO:0005794=GO_REF:0000019, GO:0005770=GO_REF:0000019, GO:0006041=GO_REF:0000019, GO:0006044=GO_REF:0000019, GO:0006048=Reactome:REACT_22394, GO:0005829=Reactome:REACT_22233, GO:0001889=GO_REF:0000019, GO:0004343=Reactome:REACT_22233, GO:0000139=GO_REF:0000039, GO:0048029=GO_REF:0000019, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0010008=GO_REF:0000039, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q96EK6 Glucosamine 6-phosphate N-acetyltransferase protein 20091207 {GO:0005793=IEA, GO:0005794=IEA, GO:0005770=IEA, GO:0006041=IEA, GO:0006044=IEA, GO:0006048=TAS, GO:0005829=TAS, GO:0001889=IEA, GO:0004343=TAS, GO:0000139=IEA, GO:0048029=IEA, GO:0006488=TAS, GO:0044267=TAS, GO:0010008=IEA, GO:0043687=TAS, GO:0018279=TAS} N-acetylglucosamine metabolic process, UDP-N-acetylglucosamine biosynthetic process, cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, glucosamine metabolic process, liver development, post-translational protein modification, protein N-linked glycosylation via asparagine Golgi apparatus, Golgi membrane, cytosol, endoplasmic reticulum-Golgi intermediate compartment, endosome membrane, late endosome glucosamine 6-phosphate N-acetyltransferase activity, monosaccharide binding Human GNPTAB UniProtKB UniProtKB {GO:0009306=GO_REF:0000019, GO:0000139=GO_REF:0000039, GO:0003976=GO_REF:0000003, GO:0005509=GO_REF:0000002, GO:0046835=GO_REF:0000019, GO:0005634=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0030154=GO_REF:0000002, GO:0008134=GO_REF:0000002} Q3T906 N-acetylglucosamine-1-phosphotransferase subunits alpha/beta protein 20130413 {GO:0009306=IEA, GO:0000139=IEA, GO:0003976=IEA, GO:0005509=IEA, GO:0046835=IEA, GO:0005634=IEA, GO:0016021=IEA, GO:0030154=IEA, GO:0008134=IEA} carbohydrate phosphorylation, cell differentiation, protein secretion Golgi membrane, integral to membrane, nucleus UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity, calcium ion binding, transcription factor binding Human UniProtKB-SubCell:SL-0134 GNPTG UniProtKB UniProtKB {GO:0005794=GO_REF:0000039, GO:0005576=GO_REF:0000039} Q9UJJ9 N-acetylglucosamine-1-phosphotransferase subunit gamma protein 20130413 {GO:0005794=IEA, GO:0005576=IEA} Golgi apparatus, extracellular region Human UniProtKB-SubCell:SL-0132 GNRH1 Reactome UniProtKB {GO:0010468=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0008285=PMID:10832105, GO:0045471=GO_REF:0000019, GO:0007267=PMID:1310542, GO:0031960=GO_REF:0000019, GO:0005576=Reactome:REACT_22436, GO:0007275=GO_REF:0000019, GO:0042698=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0007165=PMID:8692981, GO:0005179=PMID:2863757, GO:0005183=GO_REF:0000002} P01148 Progonadoliberin-1 protein 20100609 {GO:0010468=IEA, GO:0007565=IEA, GO:0043066=IEA, GO:0008285=TAS, GO:0045471=IEA, GO:0007267=TAS, GO:0031960=IEA, GO:0005576=TAS, GO:0007275=IEA, GO:0042698=IEA, GO:0005615=IEA, GO:0007165=TAS, GO:0005179=TAS, GO:0005183=IEA} cell-cell signaling, female pregnancy, multicellular organismal development, negative regulation of apoptotic process, negative regulation of cell proliferation, ovulation cycle, regulation of gene expression, response to corticosteroid stimulus, response to ethanol, signal transduction extracellular region, extracellular space gonadotropin hormone-releasing hormone activity, hormone activity Human GNRH2 Reactome UniProtKB {GO:0007165=PMID:9419371, GO:0005179=GO_REF:0000037, GO:0005576=Reactome:REACT_22436, GO:0007275=GO_REF:0000002} O43555 Progonadoliberin-2 protein 20100609 {GO:0007165=TAS, GO:0005179=IEA, GO:0005576=TAS, GO:0007275=IEA} multicellular organismal development, signal transduction extracellular region hormone activity Human GNRHR GOC UniProtKB {GO:0005886=Reactome:REACT_22436, GO:0007186=PMID:8386108, GO:0016020=PMID:9259321, GO:0005887=PMID:8386108, GO:0007275=PMID:10686191, GO:0097211=PMID:8386108, GO:0004968=GO_REF:0000002} P30968 Gonadotropin-releasing hormone receptor protein 20130413 {GO:0005886=TAS, GO:0007186=TAS, GO:0016020=TAS, GO:0005887=TAS, GO:0007275=TAS, GO:0097211=TAS, GO:0004968=IEA} G-protein coupled receptor signaling pathway, cellular response to gonadotropin-releasing hormone, multicellular organismal development integral to plasma membrane, membrane, plasma membrane gonadotropin-releasing hormone receptor activity Human GNS IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0005975=Reactome:REACT_474, GO:0042340=Reactome:REACT_121313, GO:0006027=PMID:3689315, GO:0044281=Reactome:REACT_111217, GO:0008484=PMID:15962010, GO:0008449=GO_REF:0000003, GO:0030203=Reactome:REACT_121315, GO:0005764=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0043202=Reactome:REACT_120828, GO:0042339=Reactome:REACT_121288} P15586 N-acetylglucosamine-6-sulfatase protein 20130415 {GO:0005515=IPI, GO:0005975=TAS, GO:0042340=TAS, GO:0006027=TAS, GO:0044281=TAS, GO:0008484=IDA, GO:0008449=IEA, GO:0030203=TAS, GO:0005764=IEA, GO:0046872=IEA, GO:0043202=TAS, GO:0042339=TAS} carbohydrate metabolic process, glycosaminoglycan catabolic process, glycosaminoglycan metabolic process, keratan sulfate catabolic process, keratan sulfate metabolic process, small molecule metabolic process lysosomal lumen, lysosome N-acetylglucosamine-6-sulfatase activity, metal ion binding, protein binding, sulfuric ester hydrolase activity Human UniProtKB:P16333 GOLGA1 PINC UniProtKB {GO:0005802=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0005794=PMID:9324025, GO:0032580=GO_REF:0000039, GO:0000042=GO_REF:0000002} Q92805 Golgin subfamily A member 1 protein 20030904 {GO:0005802=IEA, GO:0048471=IEA, GO:0005794=TAS, GO:0032580=IEA, GO:0000042=IEA} protein targeting to Golgi Golgi apparatus, Golgi cisterna membrane, perinuclear region of cytoplasm, trans-Golgi network Human GOLGA2 HPA UniProtKB {GO:0005515=PMID:23455922, GO:0005801=PMID:22802641, GO:0005794=GO_REF:0000052, GO:0000139=Reactome:REACT_147881, GO:0000088=Reactome:REACT_765, GO:0032580=GO_REF:0000039, GO:0000087=Reactome:REACT_910, GO:0000278=Reactome:REACT_152} Q08379 Golgin subfamily A member 2 protein 20100326 {GO:0005515=IPI, GO:0005801=IDA, GO:0005794=IDA, GO:0000139=TAS, GO:0000088=TAS, GO:0032580=IEA, GO:0000087=TAS, GO:0000278=TAS} M phase of mitotic cell cycle, mitotic cell cycle, mitotic prophase Golgi apparatus, Golgi cisterna membrane, Golgi membrane, cis-Golgi network protein binding Human GOLGA3 HPA UniProtKB {GO:0005215=PMID:8315394, GO:0005793=GO_REF:0000019, GO:0005794=GO_REF:0000052, GO:0000139=PMID:9295333, GO:0032580=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0017119=PMID:8315394, GO:0006891=PMID:8315394, GO:0005634=GO_REF:0000052} Q08378 Golgin subfamily A member 3 protein 20111111 {GO:0005215=NAS, GO:0005793=IEA, GO:0005794=IDA, GO:0000139=TAS, GO:0032580=IEA, GO:0005730=IDA, GO:0017119=IDA, GO:0006891=NAS, GO:0005634=IDA} intra-Golgi vesicle-mediated transport Golgi apparatus, Golgi cisterna membrane, Golgi membrane, Golgi transport complex, endoplasmic reticulum-Golgi intermediate compartment, nucleolus, nucleus transporter activity Human GOLGA4 IntAct UniProtKB {GO:0005802=PMID:1400343, GO:0005515=PMID:22705394, GO:0005737=PMID:15265687, GO:0051020=PMID:14580338, GO:0005794=PMID:19224922, GO:0000139=GO_REF:0000039, GO:0043001=PMID:15265687, GO:0016192=PMID:8626529, GO:0000042=GO_REF:0000002} Q13439 Golgin subfamily A member 4 protein 20130415 {GO:0005802=TAS, GO:0005515=IPI, GO:0005737=IDA, GO:0051020=IPI, GO:0005794=IDA, GO:0000139=IEA, GO:0043001=IDA, GO:0016192=TAS, GO:0000042=IEA} Golgi to plasma membrane protein transport, protein targeting to Golgi, vesicle-mediated transport Golgi apparatus, Golgi membrane, cytoplasm, trans-Golgi network GTPase binding, protein binding Human UniProtKB:Q96NW4 GOLGA5 HPA UniProtKB {GO:0005801=PMID:12538640, GO:0017137=PMID:12538640, GO:0005794=GO_REF:0000052, GO:0000139=GO_REF:0000039, GO:0031985=PMID:12538640, GO:0007030=PMID:12538640, GO:0048193=PMID:12538640, GO:0016021=PMID:9915833, GO:0042803=PMID:9915833} Q8TBA6 Golgin subfamily A member 5 protein 20080205 {GO:0005801=IDA, GO:0017137=IDA, GO:0005794=IDA, GO:0000139=IEA, GO:0031985=IDA, GO:0007030=IMP, GO:0048193=IMP, GO:0016021=IDA, GO:0042803=IPI} Golgi organization, Golgi vesicle transport Golgi apparatus, Golgi cisterna, Golgi membrane, cis-Golgi network, integral to membrane Rab GTPase binding, protein homodimerization activity Human GOLGA6L10 null null {} null null null null {} null null null GOLGA6L9 null null {} null null null null {} null null null GOLGA7 UniProtKB UniProtKB {GO:0000139=GO_REF:0000039} Q7Z5G4 Golgin subfamily A member 7 protein 20130413 {GO:0000139=IEA} Golgi membrane Human UniProtKB-SubCell:SL-0134 GOLGA8A InterPro UniProtKB {GO:0005794=GO_REF:0000002, GO:0032580=GO_REF:0000039} J3KQL3 Golgin subfamily A member 8A protein 20130413 {GO:0005794=IEA, GO:0032580=IEA} Golgi apparatus, Golgi cisterna membrane Human InterPro:IPR024858 GOLGA8B InterPro UniProtKB {GO:0005794=GO_REF:0000002, GO:0032580=GO_REF:0000039} C9J1B5 Golgin subfamily A member 8B protein 20130413 {GO:0005794=IEA, GO:0032580=IEA} Golgi apparatus, Golgi cisterna membrane Human InterPro:IPR024858 GOLGA8H InterPro UniProtKB {GO:0005794=GO_REF:0000002} P0CJ92 Golgin subfamily A member 8H protein 20130413 {GO:0005794=IEA} Golgi apparatus Human InterPro:IPR024858 GOLGA8J InterPro UniProtKB {GO:0005794=GO_REF:0000002} H3BRU0 Golgin subfamily A member 8J protein 20130413 {GO:0005794=IEA} Golgi apparatus Human InterPro:IPR024858 GOLGB1 HPA UniProtKB {GO:0005515=PMID:16169070, GO:0005793=PMID:15308636, GO:0005794=GO_REF:0000052, GO:0005795=PMID:7691276, GO:0000139=GO_REF:0000039, GO:0007030=PMID:7691276, GO:0016021=GO_REF:0000037} Q14789 Golgin subfamily B member 1 protein 20080205 {GO:0005515=IPI, GO:0005793=IDA, GO:0005794=IDA, GO:0005795=TAS, GO:0000139=IEA, GO:0007030=TAS, GO:0016021=IEA} Golgi organization Golgi apparatus, Golgi membrane, Golgi stack, endoplasmic reticulum-Golgi intermediate compartment, integral to membrane protein binding Human GOLIM4 HPA UniProtKB {GO:0005801=PMID:9201717, GO:0005794=GO_REF:0000052, GO:0005796=PMID:9201717, GO:0032580=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0006810=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0030139=PMID:9201717, GO:0016021=GO_REF:0000037, GO:0010008=GO_REF:0000039} O00461 Golgi integral membrane protein 4 protein 20101115 {GO:0005801=TAS, GO:0005794=IDA, GO:0005796=TAS, GO:0032580=IEA, GO:0005730=IDA, GO:0006810=IEA, GO:0005634=IDA, GO:0030139=TAS, GO:0016021=IEA, GO:0010008=IEA} transport Golgi apparatus, Golgi cisterna membrane, Golgi lumen, cis-Golgi network, endocytic vesicle, endosome membrane, integral to membrane, nucleolus, nucleus Human GOLM1 HPA UniProtKB {GO:0005515=PMID:21280149, GO:0005794=GO_REF:0000052, GO:0005887=PMID:10831838} Q8NBJ4 Golgi membrane protein 1 protein 20081203 {GO:0005515=IPI, GO:0005794=IDA, GO:0005887=TAS} Golgi apparatus, integral to plasma membrane protein binding Human GOLPH3 HPA UniProtKB {GO:0005802=PMID:19553991, GO:0005515=PMID:22190034, GO:0031965=GO_REF:0000052, GO:0032008=PMID:19553991, GO:0010821=PMID:16263763, GO:0005886=GO_REF:0000052, GO:0008283=PMID:19553991, GO:0008289=GO_REF:0000037, GO:0005829=PMID:16263763, GO:0005739=PMID:16263763, GO:0005758=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0032580=GO_REF:0000039, GO:0005768=GO_REF:0000039} Q9H4A6 Golgi phosphoprotein 3 protein 20111111 {GO:0005802=IDA, GO:0005515=IPI, GO:0031965=IDA, GO:0032008=IMP, GO:0010821=IDA, GO:0005886=IDA, GO:0008283=IMP, GO:0008289=IEA, GO:0005829=IDA, GO:0005739=IDA, GO:0005758=IEA, GO:0005737=IDA, GO:0032580=IEA, GO:0005768=IEA} cell proliferation, positive regulation of TOR signaling cascade, regulation of mitochondrion organization Golgi cisterna membrane, cytoplasm, cytosol, endosome, mitochondrial intermembrane space, mitochondrion, nuclear membrane, plasma membrane, trans-Golgi network lipid binding, protein binding Human GOLPH3L IntAct UniProtKB {GO:0005515=PMID:23275563, GO:0032580=GO_REF:0000039, GO:0008289=GO_REF:0000037} Q9H4A5 Golgi phosphoprotein 3-like protein 20130415 {GO:0005515=IPI, GO:0032580=IEA, GO:0008289=IEA} Golgi cisterna membrane lipid binding, protein binding Human UniProtKB:P42858 GOLT1B GOC UniProtKB {GO:0007165=PMID:12761501, GO:0000139=GO_REF:0000039, GO:0005783=GO_REF:0000054, GO:0004871=PMID:12761501, GO:0016021=GO_REF:0000037, GO:0043123=PMID:12761501, GO:0015031=GO_REF:0000037, GO:0016192=GO_REF:0000002} Q9Y3E0 Vesicle transport protein GOT1B protein 20130413 {GO:0007165=IMP, GO:0000139=IEA, GO:0005783=IDA, GO:0004871=IMP, GO:0016021=IEA, GO:0043123=IMP, GO:0015031=IEA, GO:0016192=IEA} positive regulation of I-kappaB kinase/NF-kappaB cascade, protein transport, signal transduction, vesicle-mediated transport Golgi membrane, endoplasmic reticulum, integral to membrane signal transducer activity Human GON4L HPA UniProtKB {GO:0006355=GO_REF:0000002, GO:0003682=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000002} Q3T8J9 GON-4-like protein protein 20111111 {GO:0006355=IEA, GO:0003682=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA} regulation of transcription, DNA-dependent nucleolus, nucleus DNA binding, chromatin binding NOT Human GOPC HPA UniProtKB {GO:0005515=PMID:11707463, GO:0005794=GO_REF:0000052, GO:0030054=GO_REF:0000037, GO:0005886=PMID:11707463, GO:0007289=GO_REF:0000019, GO:0043004=PMID:11707463, GO:0014069=GO_REF:0000039, GO:0045176=PMID:11707463, GO:0006893=PMID:11707463, GO:0015031=GO_REF:0000037, GO:0008022=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0044325=PMID:11707463, GO:0006888=PMID:11707463, GO:0005109=GO_REF:0000019, GO:0043234=PMID:18468998, GO:0005737=GO_REF:0000052, GO:0005083=GO_REF:0000019, GO:0016020=PMID:11707463, GO:0000139=GO_REF:0000039, GO:0045211=GO_REF:0000037, GO:0051260=PMID:11707463, GO:0030140=PMID:11384996} Q9HD26 Golgi-associated PDZ and coiled-coil motif-containing protein protein 20100326 {GO:0005515=IPI, GO:0005794=IDA, GO:0030054=IEA, GO:0005886=NAS, GO:0007289=IEA, GO:0043004=NAS, GO:0014069=IEA, GO:0045176=NAS, GO:0006893=NAS, GO:0015031=IEA, GO:0008022=IEA, GO:0042803=IEA, GO:0044325=IPI, GO:0006888=NAS, GO:0005109=IEA, GO:0043234=IDA, GO:0005737=IDA, GO:0005083=IEA, GO:0016020=IDA, GO:0000139=IEA, GO:0045211=IEA, GO:0051260=IPI, GO:0030140=NAS} ER to Golgi vesicle-mediated transport, Golgi to plasma membrane transport, apical protein localization, cytoplasmic sequestering of CFTR protein, protein homooligomerization, protein transport, spermatid nucleus differentiation Golgi apparatus, Golgi membrane, cell junction, cytoplasm, membrane, plasma membrane, postsynaptic density, postsynaptic membrane, protein complex, trans-Golgi network transport vesicle frizzled binding, ion channel binding, protein C-terminus binding, protein binding, protein homodimerization activity, small GTPase regulator activity Human GORAB HPA UniProtKB {GO:0005515=PMID:15781263, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q5T7V8 RAB6-interacting golgin protein 20111111 {GO:0005515=IPI, GO:0005737=IDA, GO:0005794=IDA, GO:0005730=IDA, GO:0005634=IDA} Golgi apparatus, cytoplasm, nucleolus, nucleus protein binding Human GORASP1 Reactome UniProtKB {GO:0005794=GO_REF:0000019, GO:0000139=Reactome:REACT_147881, GO:0000088=Reactome:REACT_765, GO:0000087=Reactome:REACT_910, GO:0000278=Reactome:REACT_152, GO:0015031=GO_REF:0000037} Q9BQQ3 Golgi reassembly-stacking protein 1 protein 20120328 {GO:0005794=IEA, GO:0000139=TAS, GO:0000088=TAS, GO:0000087=TAS, GO:0000278=TAS, GO:0015031=IEA} M phase of mitotic cell cycle, mitotic cell cycle, mitotic prophase, protein transport Golgi apparatus, Golgi membrane Human GORASP2 HPA UniProtKB {GO:0005515=PMID:21884936, GO:0006996=PMID:21515684, GO:0005794=GO_REF:0000052, GO:0000139=Reactome:REACT_147850, GO:0000088=Reactome:REACT_765, GO:0016020=PMID:21515684, GO:0000087=Reactome:REACT_910, GO:0000278=Reactome:REACT_152} Q9H8Y8 Golgi reassembly-stacking protein 2 protein 20110516 {GO:0005515=IPI, GO:0006996=IMP, GO:0005794=IDA, GO:0000139=TAS, GO:0000088=TAS, GO:0016020=TAS, GO:0000087=TAS, GO:0000278=TAS} M phase of mitotic cell cycle, mitotic cell cycle, mitotic prophase, organelle organization Golgi apparatus, Golgi membrane, membrane protein binding Human GOSR1 BHF-UCL UniProtKB {GO:0006888=GO_REF:0000019, GO:0005484=PMID:15215310, GO:0005801=GO_REF:0000019, GO:0005794=PMID:15215310, GO:0000139=PMID:21669198, GO:0042147=PMID:15215310, GO:0031201=PMID:15215310, GO:0006891=PMID:8636227, GO:0016021=GO_REF:0000019, GO:0015031=GO_REF:0000037} O95249 Golgi SNAP receptor complex member 1 protein 20130121 {GO:0006888=IEA, GO:0005484=IDA, GO:0005801=IEA, GO:0005794=IDA, GO:0000139=IDA, GO:0042147=IDA, GO:0031201=TAS, GO:0006891=TAS, GO:0016021=IEA, GO:0015031=IEA} ER to Golgi vesicle-mediated transport, intra-Golgi vesicle-mediated transport, protein transport, retrograde transport, endosome to Golgi Golgi apparatus, Golgi membrane, SNARE complex, cis-Golgi network, integral to membrane SNAP receptor activity Human GOSR2 Reactome UniProtKB {GO:0006888=PMID:9349823, GO:0005215=PMID:9349823, GO:0000139=Reactome:REACT_116129, GO:0006944=PMID:9349823, GO:0005795=GO_REF:0000002, GO:0006810=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0006987=Reactome:REACT_18368, GO:0015031=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0030968=Reactome:REACT_18356} O14653 Golgi SNAP receptor complex member 2 protein 20130301 {GO:0006888=TAS, GO:0005215=TAS, GO:0000139=TAS, GO:0006944=TAS, GO:0005795=IEA, GO:0006810=IEA, GO:0016021=IEA, GO:0006987=TAS, GO:0015031=IEA, GO:0044267=TAS, GO:0030968=TAS} ER to Golgi vesicle-mediated transport, activation of signaling protein activity involved in unfolded protein response, cellular membrane fusion, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, protein transport, transport Golgi membrane, Golgi stack, integral to membrane transporter activity Human GOT1 Reactome UniProtKB {GO:0031406=GO_REF:0000019, GO:0006531=GO_REF:0000024, GO:0006532=GO_REF:0000019, GO:0006533=PMID:2241899, GO:0008483=Reactome:REACT_75811, GO:0006094=Reactome:REACT_1520, GO:0044281=Reactome:REACT_111217, GO:0047801=GO_REF:0000024, GO:0005764=GO_REF:0000019, GO:0019551=GO_REF:0000019, GO:0019550=GO_REF:0000019, GO:0005829=Reactome:REACT_75811, GO:0034641=Reactome:REACT_13, GO:0005737=PMID:7060339, GO:0019509=Reactome:REACT_75881, GO:0006595=Reactome:REACT_14820, GO:0006103=GO_REF:0000024, GO:0006006=Reactome:REACT_723, GO:0043679=GO_REF:0000019, GO:0004609=GO_REF:0000019, GO:0004069=Reactome:REACT_2078, GO:0080130=GO_REF:0000003, GO:0006520=GO_REF:0000002, GO:0032869=PMID:8396422, GO:0009058=GO_REF:0000002, GO:0006536=GO_REF:0000024, GO:0005975=Reactome:REACT_474, GO:0006107=GO_REF:0000019, GO:0008652=Reactome:REACT_238, GO:0055089=GO_REF:0000019, GO:0051384=PMID:8396422, GO:0000096=Reactome:REACT_115639, GO:0006114=GO_REF:0000024, GO:0030170=GO_REF:0000002} P17174 Aspartate aminotransferase, cytoplasmic protein 20110516 {GO:0031406=IEA, GO:0006531=ISS, GO:0006532=IEA, GO:0006533=IDA, GO:0008483=TAS, GO:0006094=TAS, GO:0044281=TAS, GO:0047801=ISS, GO:0005764=IEA, GO:0019551=IEA, GO:0019550=IEA, GO:0005829=TAS, GO:0034641=TAS, GO:0005737=IDA, GO:0019509=TAS, GO:0006595=TAS, GO:0006103=ISS, GO:0006006=TAS, GO:0043679=IEA, GO:0004609=IEA, GO:0004069=TAS, GO:0080130=IEA, GO:0006520=IEA, GO:0032869=IEP, GO:0009058=IEA, GO:0006536=ISS, GO:0005975=TAS, GO:0006107=IEA, GO:0008652=TAS, GO:0055089=IEA, GO:0051384=IEP, GO:0000096=TAS, GO:0006114=ISS, GO:0030170=IEA} 2-oxoglutarate metabolic process, L-methionine salvage from methylthioadenosine, aspartate biosynthetic process, aspartate catabolic process, aspartate metabolic process, biosynthetic process, carbohydrate metabolic process, cellular amino acid biosynthetic process, cellular amino acid metabolic process, cellular nitrogen compound metabolic process, cellular response to insulin stimulus, fatty acid homeostasis, gluconeogenesis, glucose metabolic process, glutamate catabolic process to 2-oxoglutarate, glutamate catabolic process to aspartate, glutamate metabolic process, glycerol biosynthetic process, oxaloacetate metabolic process, polyamine metabolic process, response to glucocorticoid stimulus, small molecule metabolic process, sulfur amino acid metabolic process axon terminus, cytoplasm, cytosol, lysosome L-aspartate:2-oxoglutarate aminotransferase activity, L-cysteine:2-oxoglutarate aminotransferase activity, L-phenylalanine:2-oxoglutarate aminotransferase activity, carboxylic acid binding, phosphatidylserine decarboxylase activity, pyridoxal phosphate binding, transaminase activity Human GOT1L1 UniProtKB UniProtKB {GO:0006520=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0009058=GO_REF:0000002, GO:0030170=GO_REF:0000002, GO:0008483=GO_REF:0000037} Q8NHS2 Putative aspartate aminotransferase, cytoplasmic 2 protein 20130413 {GO:0006520=IEA, GO:0005737=IEA, GO:0009058=IEA, GO:0030170=IEA, GO:0008483=IEA} biosynthetic process, cellular amino acid metabolic process cytoplasm pyridoxal phosphate binding, transaminase activity Human UniProtKB-SubCell:SL-0086 GOT2 BHF-UCL UniProtKB {GO:0006531=GO_REF:0000024, GO:0006532=GO_REF:0000019, GO:0005886=PMID:9537447, GO:0006533=PMID:2567216, GO:0045471=PMID:9537447, GO:0005743=GO_REF:0000019, GO:0006094=Reactome:REACT_1520, GO:0044281=Reactome:REACT_111217, GO:0019551=GO_REF:0000019, GO:0019550=GO_REF:0000019, GO:0005739=GO_REF:0000024, GO:0034641=Reactome:REACT_13, GO:0005759=Reactome:REACT_1632, GO:0006103=GO_REF:0000024, GO:0006006=Reactome:REACT_723, GO:0004069=Reactome:REACT_1632, GO:0080130=GO_REF:0000003, GO:0006520=GO_REF:0000002, GO:0009058=GO_REF:0000002, GO:0006536=GO_REF:0000024, GO:0005975=Reactome:REACT_474, GO:0006107=GO_REF:0000019, GO:0008652=Reactome:REACT_238, GO:0019470=PMID:21998747, GO:0030170=GO_REF:0000002, GO:0016212=GO_REF:0000003, GO:0015908=PMID:9537447} P00505 Aspartate aminotransferase, mitochondrial protein 20120710 {GO:0006531=ISS, GO:0006532=IEA, GO:0005886=IDA, GO:0006533=IDA, GO:0045471=IDA, GO:0005743=IEA, GO:0006094=TAS, GO:0044281=TAS, GO:0019551=IEA, GO:0019550=IEA, GO:0005739=ISS, GO:0034641=TAS, GO:0005759=TAS, GO:0006103=ISS, GO:0006006=TAS, GO:0004069=EXP, GO:0080130=IEA, GO:0006520=IEA, GO:0009058=IEA, GO:0006536=ISS, GO:0005975=TAS, GO:0006107=IEA, GO:0008652=TAS, GO:0019470=TAS, GO:0030170=IEA, GO:0016212=IEA, GO:0015908=IEP} 2-oxoglutarate metabolic process, 4-hydroxyproline catabolic process, aspartate biosynthetic process, aspartate catabolic process, aspartate metabolic process, biosynthetic process, carbohydrate metabolic process, cellular amino acid biosynthetic process, cellular amino acid metabolic process, cellular nitrogen compound metabolic process, fatty acid transport, gluconeogenesis, glucose metabolic process, glutamate catabolic process to 2-oxoglutarate, glutamate catabolic process to aspartate, glutamate metabolic process, oxaloacetate metabolic process, response to ethanol, small molecule metabolic process mitochondrial inner membrane, mitochondrial matrix, mitochondrion, plasma membrane L-aspartate:2-oxoglutarate aminotransferase activity, L-phenylalanine:2-oxoglutarate aminotransferase activity, kynurenine-oxoglutarate transaminase activity, pyridoxal phosphate binding Human GP1BA GOC UniProtKB {GO:0005515=PMID:15039442, GO:0005886=Reactome:REACT_24010, GO:0015057=PMID:12855810, GO:0030168=Reactome:REACT_798, GO:0031362=GO_REF:0000019, GO:0007599=GO_REF:0000019, GO:0000902=GO_REF:0000019, GO:0016020=PMID:15297306, GO:0030193=PMID:12855810, GO:0070493=PMID:3759960, GO:0005887=PMID:3353370, GO:0007596=Reactome:REACT_2051, GO:0007597=Reactome:REACT_326, GO:0007155=PMID:9410473, GO:0042730=PMID:12855810, GO:0007166=PMID:3353370} P07359 Platelet glycoprotein Ib alpha chain protein 20130413 {GO:0005515=IPI, GO:0005886=TAS, GO:0015057=TAS, GO:0030168=TAS, GO:0031362=IEA, GO:0007599=IEA, GO:0000902=IEA, GO:0016020=IDA, GO:0030193=TAS, GO:0070493=TAS, GO:0005887=TAS, GO:0007596=TAS, GO:0007597=TAS, GO:0007155=IDA, GO:0042730=IDA, GO:0007166=TAS} blood coagulation, blood coagulation, intrinsic pathway, cell adhesion, cell morphogenesis, cell surface receptor signaling pathway, fibrinolysis, hemostasis, platelet activation, regulation of blood coagulation, thrombin receptor signaling pathway anchored to external side of plasma membrane, integral to plasma membrane, membrane, plasma membrane protein binding, thrombin receptor activity Human GP1BB BHF-UCL UniProtKB {GO:0005515=PMID:4044584, GO:0005886=Reactome:REACT_24010, GO:0007596=Reactome:REACT_2051, GO:0005887=PMID:3353370, GO:0007597=Reactome:REACT_326, GO:0030168=Reactome:REACT_798, GO:0007155=GO_REF:0000037, GO:0007166=PMID:3353370, GO:0004888=PMID:3353370} P13224 Platelet glycoprotein Ib beta chain protein 20080914 {GO:0005515=IPI, GO:0005886=TAS, GO:0007596=TAS, GO:0005887=NAS, GO:0007597=TAS, GO:0030168=TAS, GO:0007155=IEA, GO:0007166=NAS, GO:0004888=NAS} blood coagulation, blood coagulation, intrinsic pathway, cell adhesion, cell surface receptor signaling pathway, platelet activation integral to plasma membrane, plasma membrane protein binding, transmembrane signaling receptor activity Human UniProtKB:P21333 GP2 UniProtKB UniProtKB {GO:0002412=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0031225=GO_REF:0000037, GO:0003823=GO_REF:0000019} P55259 Pancreatic secretory granule membrane major glycoprotein GP2 protein 20130413 {GO:0002412=IEA, GO:0016324=IEA, GO:0005576=IEA, GO:0031225=IEA, GO:0003823=IEA} antigen transcytosis by M cells in mucosal-associated lymphoid tissue anchored to membrane, apical plasma membrane, extracellular region antigen binding Human UniProtKB-SubCell:SL-0243 GP5 Reactome UniProtKB {GO:0010544=GO_REF:0000019, GO:0005886=Reactome:REACT_24010, GO:0007160=GO_REF:0000019, GO:0007596=Reactome:REACT_2051, GO:0005887=PMID:7690959, GO:0007597=Reactome:REACT_326, GO:0005518=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0007155=PMID:7690959} P40197 Platelet glycoprotein V protein 20130213 {GO:0010544=IEA, GO:0005886=TAS, GO:0007160=IEA, GO:0007596=TAS, GO:0005887=TAS, GO:0007597=TAS, GO:0005518=IEA, GO:0030168=TAS, GO:0007155=NAS} blood coagulation, blood coagulation, intrinsic pathway, cell adhesion, cell-matrix adhesion, negative regulation of platelet activation, platelet activation integral to plasma membrane, plasma membrane collagen binding Human GP6 IntAct UniProtKB {GO:0005515=PMID:1715582, GO:0005886=Reactome:REACT_23800, GO:0007596=Reactome:REACT_604, GO:0005887=GO_REF:0000019, GO:0005518=PMID:11027634, GO:0030168=Reactome:REACT_798, GO:0004872=PMID:11027634, GO:0050900=Reactome:REACT_12051, GO:0007167=PMID:9153205, GO:0004888=PMID:10822077} Q9HCN6 Platelet glycoprotein VI protein 20130415 {GO:0005515=IPI, GO:0005886=TAS, GO:0007596=TAS, GO:0005887=IEA, GO:0005518=TAS, GO:0030168=TAS, GO:0004872=TAS, GO:0050900=TAS, GO:0007167=TAS, GO:0004888=TAS} blood coagulation, enzyme linked receptor protein signaling pathway, leukocyte migration, platelet activation integral to plasma membrane, plasma membrane collagen binding, protein binding, receptor activity, transmembrane signaling receptor activity Human UniProtKB:P07948 GP9 Reactome UniProtKB {GO:0005886=Reactome:REACT_24010, GO:0007596=Reactome:REACT_2051, GO:0005887=PMID:2771955, GO:0007597=Reactome:REACT_326, GO:0030168=Reactome:REACT_798, GO:0007155=GO_REF:0000037} P14770 Platelet glycoprotein IX protein 20130213 {GO:0005886=TAS, GO:0007596=TAS, GO:0005887=TAS, GO:0007597=TAS, GO:0030168=TAS, GO:0007155=IEA} blood coagulation, blood coagulation, intrinsic pathway, cell adhesion, platelet activation integral to plasma membrane, plasma membrane Human GPA33 PINC UniProtKB {GO:0005887=PMID:9012807, GO:0004872=PMID:9012807} Q99795 Cell surface A33 antigen protein 20030904 {GO:0005887=TAS, GO:0004872=TAS} integral to plasma membrane receptor activity Human GPAA1 Reactome UniProtKB {GO:0006501=Reactome:REACT_1853, GO:0005515=PMID:10793132, GO:0034235=PMID:14660601, GO:0006461=PMID:14660601, GO:0015631=PMID:12052837, GO:0016255=Reactome:REACT_1830, GO:0005789=Reactome:REACT_1777, GO:0042765=PMID:15713669, GO:0006621=PMID:12052837, GO:0003923=PMID:9468317, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} O43292 Glycosylphosphatidylinositol anchor attachment 1 protein protein 20130213 {GO:0006501=TAS, GO:0005515=IPI, GO:0034235=IMP, GO:0006461=NAS, GO:0015631=NAS, GO:0016255=TAS, GO:0005789=TAS, GO:0042765=TAS, GO:0006621=NAS, GO:0003923=NAS, GO:0044267=TAS, GO:0043687=TAS} C-terminal protein lipidation, attachment of GPI anchor to protein, cellular protein metabolic process, post-translational protein modification, protein complex assembly, protein retention in ER lumen GPI-anchor transamidase complex, endoplasmic reticulum membrane GPI anchor binding, GPI-anchor transamidase activity, protein binding, tubulin binding Human GPAM Reactome UniProtKB {GO:0006637=GO_REF:0000019, GO:0070970=GO_REF:0000019, GO:0070236=GO_REF:0000019, GO:0005743=GO_REF:0000019, GO:0055089=GO_REF:0000019, GO:0005741=Reactome:REACT_147810, GO:0004366=PMID:18238778, GO:0044281=Reactome:REACT_111217, GO:0008654=GO_REF:0000002, GO:0009749=GO_REF:0000019, GO:0042104=GO_REF:0000019, GO:0051607=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0006631=GO_REF:0000019, GO:0019432=Reactome:REACT_1190, GO:0016024=GO_REF:0000041, GO:0055091=GO_REF:0000019, GO:0050707=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0040018=GO_REF:0000019, GO:0006644=Reactome:REACT_120870, GO:0006654=Reactome:REACT_120906, GO:0044255=Reactome:REACT_22279, GO:0046474=Reactome:REACT_121401} Q9HCL2 Glycerol-3-phosphate acyltransferase 1, mitochondrial protein 20130301 {GO:0006637=IEA, GO:0070970=IEA, GO:0070236=IEA, GO:0005743=IEA, GO:0055089=IEA, GO:0005741=TAS, GO:0004366=IMP, GO:0044281=TAS, GO:0008654=IEA, GO:0009749=IEA, GO:0042104=IEA, GO:0051607=IEA, GO:0016020=IEA, GO:0006631=IEA, GO:0019432=TAS, GO:0016024=IEA, GO:0055091=IEA, GO:0050707=IEA, GO:0016021=IEA, GO:0040018=IEA, GO:0006644=TAS, GO:0006654=TAS, GO:0044255=TAS, GO:0046474=TAS} CDP-diacylglycerol biosynthetic process, acyl-CoA metabolic process, cellular lipid metabolic process, defense response to virus, fatty acid homeostasis, fatty acid metabolic process, glycerophospholipid biosynthetic process, interleukin-2 secretion, negative regulation of activation-induced cell death of T cells, phosphatidic acid biosynthetic process, phospholipid biosynthetic process, phospholipid homeostasis, phospholipid metabolic process, positive regulation of activated T cell proliferation, positive regulation of multicellular organism growth, regulation of cytokine secretion, response to glucose stimulus, small molecule metabolic process, triglyceride biosynthetic process integral to membrane, membrane, mitochondrial inner membrane, mitochondrial outer membrane glycerol-3-phosphate O-acyltransferase activity Human GPANK1 InterPro UniProtKB {GO:0003676=GO_REF:0000002} O95872 G patch domain and ankyrin repeat-containing protein 1 protein 20130413 {GO:0003676=IEA} nucleic acid binding Human InterPro:IPR000467 GPAT2 Reactome UniProtKB {GO:0004366=GO_REF:0000024, GO:0005741=Reactome:REACT_121291, GO:0008654=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0006072=GO_REF:0000024, GO:0005739=GO_REF:0000024, GO:0016020=GO_REF:0000002, GO:0019432=GO_REF:0000024, GO:0016024=GO_REF:0000041, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0006654=Reactome:REACT_120906, GO:0046474=Reactome:REACT_121401} Q6NUI2 Glycerol-3-phosphate acyltransferase 2, mitochondrial protein 20130301 {GO:0004366=ISS, GO:0005741=TAS, GO:0008654=IEA, GO:0044281=TAS, GO:0006072=ISS, GO:0005739=ISS, GO:0016020=IEA, GO:0019432=ISS, GO:0016024=IEA, GO:0016021=IEA, GO:0006644=TAS, GO:0006654=TAS, GO:0046474=TAS} CDP-diacylglycerol biosynthetic process, glycerol-3-phosphate metabolic process, glycerophospholipid biosynthetic process, phosphatidic acid biosynthetic process, phospholipid biosynthetic process, phospholipid metabolic process, small molecule metabolic process, triglyceride biosynthetic process integral to membrane, membrane, mitochondrial outer membrane, mitochondrion glycerol-3-phosphate O-acyltransferase activity Human GPATCH1 UniProtKB UniProtKB {GO:0000398=PMID:11991638, GO:0071013=PMID:11991638, GO:0003676=GO_REF:0000002} Q9BRR8 G patch domain-containing protein 1 protein 20110302 {GO:0000398=IC, GO:0071013=IDA, GO:0003676=IEA} mRNA splicing, via spliceosome catalytic step 2 spliceosome nucleic acid binding Human GPATCH2 UniProtKB UniProtKB {GO:0010923=PMID:19389623, GO:0003676=GO_REF:0000002} Q9NW75 G patch domain-containing protein 2 protein 20111103 {GO:0010923=IDA, GO:0003676=IEA} negative regulation of phosphatase activity nucleic acid binding Human GPATCH4 InterPro UniProtKB {GO:0003676=GO_REF:0000002} Q5T3I0 G patch domain-containing protein 4 protein 20130413 {GO:0003676=IEA} nucleic acid binding Human InterPro:IPR000467 GPATCH8 IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0008270=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0003676=GO_REF:0000002} Q9UKJ3 G patch domain-containing protein 8 protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0003674=ND, GO:0008270=IEA, GO:0005575=ND, GO:0003676=IEA} biological_process cellular_component molecular_function, nucleic acid binding, protein binding, zinc ion binding Human UniProtKB:P54253 GPBP1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0003700=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0045893=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q86WP2 Vasculin protein 20130413 {GO:0005737=IEA, GO:0003700=IEA, GO:0005634=IEA, GO:0045893=IEA, GO:0003677=IEA, GO:0006351=IEA} positive regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0086 GPBP1L1 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9HC44 Vasculin-like protein 1 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding Human UniProtKB-SubCell:SL-0191 GPC1 Reactome UniProtKB {GO:0005886=Reactome:REACT_160272, GO:0007603=Reactome:REACT_160125, GO:0044281=Reactome:REACT_111217, GO:0031225=GO_REF:0000037, GO:0005615=GO_REF:0000039, GO:0014037=GO_REF:0000024, GO:0007411=Reactome:REACT_18266, GO:0030200=PMID:12732622, GO:0030204=Reactome:REACT_121206, GO:2001016=GO_REF:0000024, GO:0030203=Reactome:REACT_121408, GO:0043202=Reactome:REACT_121392, GO:0005507=PMID:12732622, GO:0017134=GO_REF:0000024, GO:0005796=Reactome:REACT_121320, GO:0005975=Reactome:REACT_474, GO:0005578=GO_REF:0000024, GO:0006027=Reactome:REACT_120752, GO:0043395=GO_REF:0000002, GO:0001523=Reactome:REACT_24968, GO:0006024=Reactome:REACT_121248, GO:0032288=GO_REF:0000024, GO:0005887=PMID:2148568, GO:0043236=GO_REF:0000024, GO:0040037=GO_REF:0000024, GO:0045121=PMID:12732622, GO:0005768=GO_REF:0000039} P35052 Glypican-1 protein 20130301 {GO:0005886=TAS, GO:0007603=TAS, GO:0044281=TAS, GO:0031225=IEA, GO:0005615=IEA, GO:0014037=ISS, GO:0007411=TAS, GO:0030200=IDA, GO:0030204=TAS, GO:2001016=ISS, GO:0030203=TAS, GO:0043202=TAS, GO:0005507=IDA, GO:0017134=ISS, GO:0005796=TAS, GO:0005975=TAS, GO:0005578=ISS, GO:0006027=TAS, GO:0043395=IEA, GO:0001523=TAS, GO:0006024=TAS, GO:0032288=ISS, GO:0005887=TAS, GO:0043236=ISS, GO:0040037=ISS, GO:0045121=IDA, GO:0005768=IEA} Schwann cell differentiation, axon guidance, carbohydrate metabolic process, chondroitin sulfate metabolic process, glycosaminoglycan biosynthetic process, glycosaminoglycan catabolic process, glycosaminoglycan metabolic process, heparan sulfate proteoglycan catabolic process, myelin assembly, negative regulation of fibroblast growth factor receptor signaling pathway, phototransduction, visible light, positive regulation of skeletal muscle cell differentiation, retinoid metabolic process, small molecule metabolic process Golgi lumen, anchored to membrane, endosome, extracellular space, integral to plasma membrane, lysosomal lumen, membrane raft, plasma membrane, proteinaceous extracellular matrix copper ion binding, fibroblast growth factor binding, heparan sulfate proteoglycan binding, laminin binding Human GPC2 LIFEdb UniProtKB {GO:0005886=Reactome:REACT_160272, GO:0007603=Reactome:REACT_160125, GO:0005783=GO_REF:0000054, GO:0005796=Reactome:REACT_121320, GO:0005975=Reactome:REACT_474, GO:0005578=GO_REF:0000002, GO:0006027=Reactome:REACT_120752, GO:0043395=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0031225=GO_REF:0000037, GO:0005615=GO_REF:0000039, GO:0001523=Reactome:REACT_24968, GO:0006024=Reactome:REACT_121248, GO:0007224=GO_REF:0000019, GO:0030182=GO_REF:0000019, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408, GO:0043202=Reactome:REACT_121392} Q8N158 Glypican-2 protein 20100607 {GO:0005886=TAS, GO:0007603=TAS, GO:0005783=IDA, GO:0005796=TAS, GO:0005975=TAS, GO:0005578=IEA, GO:0006027=TAS, GO:0043395=IEA, GO:0044281=TAS, GO:0031225=IEA, GO:0005615=IEA, GO:0001523=TAS, GO:0006024=TAS, GO:0007224=IEA, GO:0030182=IEA, GO:0030204=TAS, GO:0030203=TAS, GO:0043202=TAS} carbohydrate metabolic process, chondroitin sulfate metabolic process, glycosaminoglycan biosynthetic process, glycosaminoglycan catabolic process, glycosaminoglycan metabolic process, neuron differentiation, phototransduction, visible light, retinoid metabolic process, small molecule metabolic process, smoothened signaling pathway Golgi lumen, anchored to membrane, endoplasmic reticulum, extracellular space, lysosomal lumen, plasma membrane, proteinaceous extracellular matrix heparan sulfate proteoglycan binding Human GPC3 Reactome UniProtKB {GO:0005515=PMID:17549790, GO:0045732=GO_REF:0000019, GO:0001658=GO_REF:0000019, GO:0007603=Reactome:REACT_160125, GO:0005886=Reactome:REACT_160272, GO:0060422=PMID:17549790, GO:0030324=GO_REF:0000019, GO:0050680=GO_REF:0000019, GO:2000096=GO_REF:0000019, GO:0045879=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0031225=GO_REF:0000037, GO:0030282=GO_REF:0000019, GO:0009653=PMID:8589713, GO:0005615=GO_REF:0000039, GO:0005764=GO_REF:0000019, GO:0072180=GO_REF:0000019, GO:0045807=GO_REF:0000019, GO:0030513=GO_REF:0000019, GO:0045880=GO_REF:0000019, GO:0060976=GO_REF:0000019, GO:0072138=GO_REF:0000024, GO:0009948=GO_REF:0000019, GO:0046326=GO_REF:0000019, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408, GO:0046658=GO_REF:0000019, GO:0090090=GO_REF:0000019, GO:0045926=GO_REF:0000019, GO:0043202=Reactome:REACT_121392, GO:0010171=GO_REF:0000019, GO:0005975=Reactome:REACT_474, GO:0005796=Reactome:REACT_121320, GO:0030316=GO_REF:0000019, GO:0005578=GO_REF:0000002, GO:0006027=Reactome:REACT_120752, GO:0043395=GO_REF:0000002, GO:0001523=Reactome:REACT_24968, GO:0006024=Reactome:REACT_121248, GO:0072203=GO_REF:0000019, GO:0005887=PMID:7657705, GO:0035116=GO_REF:0000019} P51654 Glypican-3 protein 20130301 {GO:0005515=IPI, GO:0045732=IEA, GO:0001658=IEA, GO:0007603=TAS, GO:0005886=TAS, GO:0060422=IDA, GO:0030324=IEA, GO:0050680=IEA, GO:2000096=IEA, GO:0045879=IEA, GO:0044281=TAS, GO:0031225=IEA, GO:0030282=IEA, GO:0009653=TAS, GO:0005615=IEA, GO:0005764=IEA, GO:0072180=IEA, GO:0045807=IEA, GO:0030513=IEA, GO:0045880=IEA, GO:0060976=IEA, GO:0072138=ISS, GO:0009948=IEA, GO:0046326=IEA, GO:0030204=TAS, GO:0030203=TAS, GO:0046658=IEA, GO:0090090=IEA, GO:0045926=IEA, GO:0043202=TAS, GO:0010171=IEA, GO:0005975=TAS, GO:0005796=TAS, GO:0030316=IEA, GO:0005578=IEA, GO:0006027=TAS, GO:0043395=IEA, GO:0001523=TAS, GO:0006024=TAS, GO:0072203=IEA, GO:0005887=TAS, GO:0035116=IEA} anatomical structure morphogenesis, anterior/posterior axis specification, body morphogenesis, bone mineralization, branching involved in ureteric bud morphogenesis, carbohydrate metabolic process, cell proliferation involved in metanephros development, chondroitin sulfate metabolic process, coronary vasculature development, embryonic hindlimb morphogenesis, glycosaminoglycan biosynthetic process, glycosaminoglycan catabolic process, glycosaminoglycan metabolic process, lung development, mesenchymal cell proliferation involved in ureteric bud development, mesonephric duct morphogenesis, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of epithelial cell proliferation, negative regulation of growth, negative regulation of smoothened signaling pathway, osteoclast differentiation, phototransduction, visible light, positive regulation of BMP signaling pathway, positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway, positive regulation of endocytosis, positive regulation of glucose import, positive regulation of protein catabolic process, positive regulation of smoothened signaling pathway, retinoid metabolic process, small molecule metabolic process Golgi lumen, anchored to membrane, anchored to plasma membrane, extracellular space, integral to plasma membrane, lysosomal lumen, lysosome, plasma membrane, proteinaceous extracellular matrix heparan sulfate proteoglycan binding, peptidyl-dipeptidase inhibitor activity, protein binding Human GPC4 Reactome UniProtKB {GO:0007603=Reactome:REACT_160125, GO:0005886=Reactome:REACT_160272, GO:0008283=PMID:9787072, GO:0005796=Reactome:REACT_121320, GO:0005975=Reactome:REACT_474, GO:0005578=GO_REF:0000002, GO:0006027=Reactome:REACT_120752, GO:0043395=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0031225=GO_REF:0000037, GO:0005615=GO_REF:0000039, GO:0009653=PMID:9787072, GO:0001523=Reactome:REACT_24968, GO:0006024=Reactome:REACT_121248, GO:0005887=PMID:9931407, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408, GO:0009897=PMID:10585884, GO:0043202=Reactome:REACT_121392} O75487 Glypican-4 protein 20130301 {GO:0007603=TAS, GO:0005886=TAS, GO:0008283=TAS, GO:0005796=TAS, GO:0005975=TAS, GO:0005578=IEA, GO:0006027=TAS, GO:0043395=IEA, GO:0044281=TAS, GO:0031225=IEA, GO:0005615=IEA, GO:0009653=TAS, GO:0001523=TAS, GO:0006024=TAS, GO:0005887=TAS, GO:0030204=TAS, GO:0030203=TAS, GO:0009897=IDA, GO:0043202=TAS} anatomical structure morphogenesis, carbohydrate metabolic process, cell proliferation, chondroitin sulfate metabolic process, glycosaminoglycan biosynthetic process, glycosaminoglycan catabolic process, glycosaminoglycan metabolic process, phototransduction, visible light, retinoid metabolic process, small molecule metabolic process Golgi lumen, anchored to membrane, external side of plasma membrane, extracellular space, integral to plasma membrane, lysosomal lumen, plasma membrane, proteinaceous extracellular matrix heparan sulfate proteoglycan binding Human GPC5 Reactome UniProtKB {GO:0005886=Reactome:REACT_160272, GO:0007603=Reactome:REACT_160125, GO:0005796=Reactome:REACT_121320, GO:0005975=Reactome:REACT_474, GO:0005578=GO_REF:0000002, GO:0006027=Reactome:REACT_120752, GO:0043395=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0031225=GO_REF:0000037, GO:0005615=GO_REF:0000039, GO:0001523=Reactome:REACT_24968, GO:0006024=Reactome:REACT_121248, GO:0005887=PMID:7657705, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408, GO:0043202=Reactome:REACT_121392} P78333 Glypican-5 protein 20130301 {GO:0005886=TAS, GO:0007603=TAS, GO:0005796=TAS, GO:0005975=TAS, GO:0005578=IEA, GO:0006027=TAS, GO:0043395=IEA, GO:0044281=TAS, GO:0031225=IEA, GO:0005615=IEA, GO:0001523=TAS, GO:0006024=TAS, GO:0005887=TAS, GO:0030204=TAS, GO:0030203=TAS, GO:0043202=TAS} carbohydrate metabolic process, chondroitin sulfate metabolic process, glycosaminoglycan biosynthetic process, glycosaminoglycan catabolic process, glycosaminoglycan metabolic process, phototransduction, visible light, retinoid metabolic process, small molecule metabolic process Golgi lumen, anchored to membrane, extracellular space, integral to plasma membrane, lysosomal lumen, plasma membrane, proteinaceous extracellular matrix heparan sulfate proteoglycan binding Human GPCPD1 Reactome UniProtKB {GO:0006629=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0006644=Reactome:REACT_120977, GO:0047389=GO_REF:0000003, GO:2001070=GO_REF:0000002, GO:0008889=GO_REF:0000002, GO:0006071=GO_REF:0000002, GO:0046474=Reactome:REACT_121401, GO:0005829=GO_REF:0000039} Q9NPB8 Glycerophosphocholine phosphodiesterase GPCPD1 protein 20130301 {GO:0006629=IEA, GO:0044281=TAS, GO:0006644=TAS, GO:0047389=IEA, GO:2001070=IEA, GO:0008889=IEA, GO:0006071=IEA, GO:0046474=TAS, GO:0005829=IEA} glycerol metabolic process, glycerophospholipid biosynthetic process, lipid metabolic process, phospholipid metabolic process, small molecule metabolic process cytosol glycerophosphocholine phosphodiesterase activity, glycerophosphodiester phosphodiesterase activity, starch binding Human GPD1 HPA UniProtKB {GO:0009331=GO_REF:0000002, GO:0004368=GO_REF:0000019, GO:0006094=GO_REF:0000019, GO:0004367=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0042803=GO_REF:0000002, GO:0046168=GO_REF:0000002, GO:0005829=Reactome:REACT_1146, GO:0005739=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0051287=GO_REF:0000019, GO:0006116=GO_REF:0000019, GO:0071356=GO_REF:0000019, GO:0019432=Reactome:REACT_1190, GO:0006644=Reactome:REACT_120870, GO:0071320=GO_REF:0000019, GO:0006654=Reactome:REACT_120906, GO:0044255=Reactome:REACT_22279, GO:0046474=Reactome:REACT_121401} P21695 "Glycerol-3-phosphate dehydrogenase ""NAD(+)"", cytoplasmic" protein 20111111 {GO:0009331=IEA, GO:0004368=IEA, GO:0006094=IEA, GO:0004367=IEA, GO:0044281=TAS, GO:0042803=IEA, GO:0046168=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0005737=IDA, GO:0051287=IEA, GO:0006116=IEA, GO:0071356=IEA, GO:0019432=TAS, GO:0006644=TAS, GO:0071320=IEA, GO:0006654=TAS, GO:0044255=TAS, GO:0046474=TAS} NADH oxidation, cellular lipid metabolic process, cellular response to cAMP, cellular response to tumor necrosis factor, gluconeogenesis, glycerol-3-phosphate catabolic process, glycerophospholipid biosynthetic process, phosphatidic acid biosynthetic process, phospholipid metabolic process, small molecule metabolic process, triglyceride biosynthetic process cytoplasm, cytosol, glycerol-3-phosphate dehydrogenase complex, mitochondrion "NAD binding, glycerol-3-phosphate dehydrogenase NAD+"" activity, glycerol-3-phosphate dehydrogenase activity, protein homodimerization activity""" Human GPD1L HPA UniProtKB {GO:0005886=PMID:17967977, GO:0019674=PMID:19745168, GO:0044281=Reactome:REACT_111217, GO:0042803=GO_REF:0000002, GO:0005829=Reactome:REACT_1146, GO:0046168=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0060373=PMID:17967977, GO:0051287=GO_REF:0000002, GO:0090038=PMID:19666841, GO:0010765=PMID:19745168, GO:0019432=Reactome:REACT_1190, GO:2000010=PMID:17967977, GO:0006654=Reactome:REACT_120906, GO:0044255=Reactome:REACT_22279, GO:0086005=PMID:17967977, GO:0009331=GO_REF:0000002, GO:0005975=GO_REF:0000002, GO:0004367=GO_REF:0000003, GO:2000649=PMID:17967977, GO:0006734=GO_REF:0000019, GO:0044325=PMID:19666841, GO:0002027=PMID:17967977, GO:0006644=Reactome:REACT_120870, GO:0046474=Reactome:REACT_121401, GO:0017080=PMID:17967977} Q8N335 Glycerol-3-phosphate dehydrogenase 1-like protein protein 20101115 {GO:0005886=IDA, GO:0019674=IMP, GO:0044281=TAS, GO:0042803=IEA, GO:0005829=TAS, GO:0046168=IEA, GO:0005737=IDA, GO:0060373=IMP, GO:0051287=IEA, GO:0090038=IMP, GO:0010765=IMP, GO:0019432=TAS, GO:2000010=IMP, GO:0006654=TAS, GO:0044255=TAS, GO:0086005=IMP, GO:0009331=IEA, GO:0005975=IEA, GO:0004367=IEA, GO:2000649=IMP, GO:0006734=IEA, GO:0044325=IPI, GO:0002027=IMP, GO:0006644=TAS, GO:0046474=TAS, GO:0017080=IMP} NAD metabolic process, NADH metabolic process, carbohydrate metabolic process, cellular lipid metabolic process, glycerol-3-phosphate catabolic process, glycerophospholipid biosynthetic process, negative regulation of protein kinase C signaling cascade, phosphatidic acid biosynthetic process, phospholipid metabolic process, positive regulation of protein localization to cell surface, positive regulation of sodium ion transport, regulation of heart rate, regulation of sodium ion transmembrane transporter activity, regulation of ventricular cardiac muscle cell action potential, regulation of ventricular cardiac muscle cell membrane depolarization, small molecule metabolic process, triglyceride biosynthetic process cytoplasm, cytosol, glycerol-3-phosphate dehydrogenase complex, plasma membrane "NAD binding, glycerol-3-phosphate dehydrogenase NAD+"" activity, ion channel binding, protein homodimerization activity, sodium channel regulator activity""" Human GPD2 Reactome UniProtKB {GO:0009331=GO_REF:0000002, GO:0052591=GO_REF:0000003, GO:0019563=GO_REF:0000041, GO:0005509=GO_REF:0000002, GO:0006094=GO_REF:0000019, GO:0005743=Reactome:REACT_16938, GO:0004368=PMID:9070847, GO:0044281=Reactome:REACT_111217, GO:0006072=GO_REF:0000019, GO:0044255=Reactome:REACT_22279} P43304 Glycerol-3-phosphate dehydrogenase, mitochondrial protein 20130301 {GO:0009331=IEA, GO:0052591=IEA, GO:0019563=IEA, GO:0005509=IEA, GO:0006094=IEA, GO:0005743=TAS, GO:0004368=TAS, GO:0044281=TAS, GO:0006072=IEA, GO:0044255=TAS} cellular lipid metabolic process, gluconeogenesis, glycerol catabolic process, glycerol-3-phosphate metabolic process, small molecule metabolic process glycerol-3-phosphate dehydrogenase complex, mitochondrial inner membrane calcium ion binding, glycerol-3-phosphate dehydrogenase activity, sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity Human GPHA2 MGI UniProtKB {GO:0005179=GO_REF:0000037, GO:0005576=PMID:12089349} Q96T91 Glycoprotein hormone alpha-2 protein 20021024 {GO:0005179=IEA, GO:0005576=IDA} extracellular region hormone activity Human GPHB5 UniProtKB UniProtKB {GO:0005179=GO_REF:0000037, GO:0005576=GO_REF:0000039} Q86YW7 Glycoprotein hormone beta-5 protein 20130413 {GO:0005179=IEA, GO:0005576=IEA} extracellular region hormone activity Human UniProtKB-SubCell:SL-0243 GPHN Reactome UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25050, GO:0006767=Reactome:REACT_11238, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0032324=Reactome:REACT_25073, GO:0005737=GO_REF:0000037, GO:0007529=GO_REF:0000019, GO:0006766=Reactome:REACT_11193, GO:0045211=GO_REF:0000039, GO:0006777=GO_REF:0000037, GO:0005856=GO_REF:0000039, GO:0016740=Reactome:REACT_25050} Q9NQX3 Gephyrin protein 20101105 {GO:0030054=IEA, GO:0005886=TAS, GO:0006767=TAS, GO:0044281=TAS, GO:0005524=IEA, GO:0046872=IEA, GO:0032324=TAS, GO:0005737=IEA, GO:0007529=IEA, GO:0006766=TAS, GO:0045211=IEA, GO:0006777=IEA, GO:0005856=IEA, GO:0016740=TAS} Mo-molybdopterin cofactor biosynthetic process, establishment of synaptic specificity at neuromuscular junction, molybdopterin cofactor biosynthetic process, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cell junction, cytoplasm, cytoskeleton, plasma membrane, postsynaptic membrane ATP binding, metal ion binding, transferase activity Human GPI HPA UniProtKB {GO:0043005=GO_REF:0000019, GO:0019242=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0046185=GO_REF:0000019, GO:0006094=Reactome:REACT_1520, GO:0005634=GO_REF:0000052, GO:0004347=Reactome:REACT_1690, GO:0044281=Reactome:REACT_111217, GO:0005615=GO_REF:0000037, GO:0006096=Reactome:REACT_1383, GO:0005829=Reactome:REACT_1690, GO:0043524=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0006959=PMID:3020690, GO:0016866=GO_REF:0000019, GO:0007611=GO_REF:0000019, GO:0006006=Reactome:REACT_723, GO:0043154=GO_REF:0000019, GO:0051156=GO_REF:0000019, GO:0005975=Reactome:REACT_474, GO:0005730=GO_REF:0000052, GO:0001525=GO_REF:0000037, GO:0005125=GO_REF:0000037, GO:0007599=PMID:7435496, GO:0048029=GO_REF:0000019, GO:0008083=GO_REF:0000037} P06744 Glucose-6-phosphate isomerase protein 20101115 {GO:0043005=IEA, GO:0019242=IEA, GO:0005886=IDA, GO:0046185=IEA, GO:0006094=TAS, GO:0005634=IDA, GO:0004347=TAS, GO:0044281=TAS, GO:0005615=IEA, GO:0006096=TAS, GO:0005829=TAS, GO:0043524=IEA, GO:0005737=IDA, GO:0006959=TAS, GO:0016866=IEA, GO:0007611=IEA, GO:0006006=TAS, GO:0043154=IEA, GO:0051156=IEA, GO:0005975=TAS, GO:0005730=IDA, GO:0001525=IEA, GO:0005125=IEA, GO:0007599=TAS, GO:0048029=IEA, GO:0008083=IEA} aldehyde catabolic process, angiogenesis, carbohydrate metabolic process, gluconeogenesis, glucose 6-phosphate metabolic process, glucose metabolic process, glycolysis, hemostasis, humoral immune response, learning or memory, methylglyoxal biosynthetic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of neuron apoptotic process, small molecule metabolic process cytoplasm, cytosol, extracellular space, neuron projection, nucleolus, nucleus, plasma membrane cytokine activity, glucose-6-phosphate isomerase activity, growth factor activity, intramolecular transferase activity, monosaccharide binding Human GPKOW HPA UniProtKB {GO:0005515=PMID:21880142, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002} Q92917 G patch domain and KOW motifs-containing protein protein 20101115 {GO:0005515=IPI, GO:0008150=ND, GO:0003674=ND, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA} biological_process nucleolus, nucleus molecular_function, nucleic acid binding, protein binding NOT Human GPLD1 UniProtKB UniProtKB {GO:0008286=PMID:18328347, GO:0008285=PMID:19135435, GO:0051047=GO_REF:0000024, GO:0002042=PMID:17720976, GO:0010897=GO_REF:0000024, GO:0005615=PMID:17761367, GO:0071467=PMID:17761367, GO:0010907=GO_REF:0000024, GO:0010983=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0071397=PMID:17761367, GO:0002062=GO_REF:0000024, GO:0035701=PMID:17368745, GO:0071277=PMID:2760042, GO:0006507=PMID:2760042, GO:0070633=GO_REF:0000024, GO:0032869=PMID:15907827, GO:0010867=GO_REF:0000024, GO:0043065=PMID:19135435, GO:0035774=GO_REF:0000024, GO:1900076=PMID:18328347, GO:0005578=GO_REF:0000024, GO:0004621=PMID:2760042, GO:0009749=PMID:15907827, GO:0010595=PMID:17720976, GO:0071401=PMID:17761367, GO:0001503=GO_REF:0000024, GO:0045919=PMID:19135435, GO:0010694=GO_REF:0000024, GO:0046470=PMID:2017684, GO:0002430=PMID:19135435, GO:0097241=PMID:17368745, GO:0017080=GO_REF:0000024} P80108 Phosphatidylinositol-glycan-specific phospholipase D protein 20120131 {GO:0008286=IDA, GO:0008285=IDA, GO:0051047=ISS, GO:0002042=IMP, GO:0010897=ISS, GO:0005615=IDA, GO:0071467=IDA, GO:0010907=ISS, GO:0010983=ISS, GO:0005737=ISS, GO:0071397=IMP, GO:0002062=ISS, GO:0035701=TAS, GO:0071277=IDA, GO:0006507=IDA, GO:0070633=ISS, GO:0032869=IDA, GO:0010867=ISS, GO:0043065=IDA, GO:0035774=ISS, GO:1900076=IDA, GO:0005578=ISS, GO:0004621=IDA, GO:0009749=IDA, GO:0010595=IMP, GO:0071401=IMP, GO:0001503=ISS, GO:0045919=IDA, GO:0010694=ISS, GO:0046470=TAS, GO:0002430=IDA, GO:0097241=TAS, GO:0017080=ISS} GPI anchor release, cell migration involved in sprouting angiogenesis, cellular response to calcium ion, cellular response to cholesterol, cellular response to insulin stimulus, cellular response to pH, cellular response to triglyceride, chondrocyte differentiation, complement receptor mediated signaling pathway, hematopoietic stem cell migration, hematopoietic stem cell migration to bone marrow, insulin receptor signaling pathway, negative regulation of cell proliferation, negative regulation of triglyceride catabolic process, ossification, phosphatidylcholine metabolic process, positive regulation of alkaline phosphatase activity, positive regulation of apoptotic process, positive regulation of cytolysis, positive regulation of endothelial cell migration, positive regulation of glucose metabolic process, positive regulation of high-density lipoprotein particle clearance, positive regulation of insulin secretion involved in cellular response to glucose stimulus, positive regulation of secretion, positive regulation of triglyceride biosynthetic process, regulation of cellular response to insulin stimulus, response to glucose stimulus, transepithelial transport cytoplasm, extracellular space, proteinaceous extracellular matrix glycosylphosphatidylinositol phospholipase D activity, sodium channel regulator activity Human GPM6A UniProtKB UniProtKB {GO:0043005=GO_REF:0000024, GO:0005262=GO_REF:0000019, GO:0003407=GO_REF:0000024, GO:0005886=GO_REF:0000024, GO:0009986=PMID:12493773, GO:0051491=GO_REF:0000024, GO:0030175=GO_REF:0000024, GO:0044295=GO_REF:0000024, GO:0007416=GO_REF:0000024, GO:0048863=PMID:19298174, GO:0043197=GO_REF:0000039, GO:0048812=GO_REF:0000024, GO:0043025=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0001764=PMID:19298174} P51674 Neuronal membrane glycoprotein M6-a protein 20120503 {GO:0043005=ISS, GO:0005262=IEA, GO:0003407=ISS, GO:0005886=ISS, GO:0009986=IDA, GO:0051491=ISS, GO:0030175=ISS, GO:0044295=ISS, GO:0007416=ISS, GO:0048863=IDA, GO:0043197=IEA, GO:0048812=ISS, GO:0043025=ISS, GO:0016021=IEA, GO:0001764=IDA} neural retina development, neuron migration, neuron projection morphogenesis, positive regulation of filopodium assembly, stem cell differentiation, synapse assembly axonal growth cone, cell surface, dendritic spine, filopodium, integral to membrane, neuron projection, neuronal cell body, plasma membrane calcium channel activity Human UniProtKB:Q812E9 GPM6B UniProtKB UniProtKB {GO:0030501=PMID:21638316, GO:0005886=GO_REF:0000024, GO:0015031=GO_REF:0000037, GO:0051893=PMID:21638316, GO:0030154=GO_REF:0000037, GO:0007399=PMID:8661015, GO:2000009=GO_REF:0000024, GO:0003674=GO_REF:0000015, GO:0085029=PMID:21638316, GO:0001503=GO_REF:0000037, GO:0051612=GO_REF:0000024, GO:0032956=PMID:21638316, GO:0045121=GO_REF:0000024, GO:0016021=GO_REF:0000029} Q13491 Neuronal membrane glycoprotein M6-b protein 20120503 {GO:0030501=IMP, GO:0005886=ISS, GO:0015031=IEA, GO:0051893=IMP, GO:0030154=IEA, GO:0007399=NAS, GO:2000009=ISS, GO:0003674=ND, GO:0085029=IMP, GO:0001503=IEA, GO:0051612=ISS, GO:0032956=IMP, GO:0045121=ISS, GO:0016021=NAS} cell differentiation, extracellular matrix assembly, negative regulation of protein localization to cell surface, negative regulation of serotonin uptake, nervous system development, ossification, positive regulation of bone mineralization, protein transport, regulation of actin cytoskeleton organization, regulation of focal adhesion assembly integral to membrane, membrane raft, plasma membrane molecular_function Human GPN1 HPA UniProtKB {GO:0005737=GO_REF:0000039, GO:0017111=GO_REF:0000002, GO:0000166=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q9HCN4 GPN-loop GTPase 1 protein 20110516 {GO:0005737=IEA, GO:0017111=IEA, GO:0000166=IEA, GO:0005525=IEA, GO:0043231=IDA} cytoplasm, intracellular membrane-bounded organelle GTP binding, nucleoside-triphosphatase activity, nucleotide binding Human GPN2 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0000166=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0005525=GO_REF:0000037} Q9H9Y4 GPN-loop GTPase 2 protein 20080610 {GO:0008150=ND, GO:0003674=ND, GO:0000166=IEA, GO:0005575=ND, GO:0005525=IEA} biological_process cellular_component GTP binding, molecular_function, nucleotide binding Human GPN3 LIFEdb UniProtKB {GO:0043234=GO_REF:0000054, GO:0000166=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q9UHW5 GPN-loop GTPase 3 protein 20100607 {GO:0043234=IDA, GO:0000166=IEA, GO:0005525=IEA} protein complex GTP binding, nucleotide binding Human GPNMB UniProtKB UniProtKB {GO:0042470=GO_REF:0000039, GO:0008285=PMID:7814155, GO:0005178=GO_REF:0000019, GO:0005887=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0030282=GO_REF:0000019, GO:0007155=GO_REF:0000019, GO:0008201=GO_REF:0000019, GO:0001649=GO_REF:0000019} Q96F58 Glycoprotein (Transmembrane) nmb protein 20130413 {GO:0042470=IEA, GO:0008285=TAS, GO:0005178=IEA, GO:0005887=IEA, GO:0016021=IEA, GO:0030282=IEA, GO:0007155=IEA, GO:0008201=IEA, GO:0001649=IEA} bone mineralization, cell adhesion, negative regulation of cell proliferation, osteoblast differentiation integral to membrane, integral to plasma membrane, melanosome heparin binding, integrin binding Human UniProtKB-KW:KW-0812 GPR1 PINC UniProtKB {GO:0007186=PMID:7851889, GO:0005887=PMID:7851889, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000002} P46091 G-protein coupled receptor 1 protein 20030904 {GO:0007186=TAS, GO:0005887=TAS, GO:0004930=IEA, GO:0016021=IEA} G-protein coupled receptor signaling pathway integral to membrane, integral to plasma membrane G-protein coupled receptor activity Human GPR107 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q5VW38 Protein GPR107 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 GPR108 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9NPR9 Protein GPR108 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 GPR113 GDB UniProtKB {GO:0007186=PMID:15203201, GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0007218=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q8IZF5 Probable G-protein coupled receptor 113 protein 20050506 {GO:0007186=TAS, GO:0005886=IEA, GO:0004930=IEA, GO:0007218=IEA, GO:0016021=IEA} G-protein coupled receptor signaling pathway, neuropeptide signaling pathway integral to membrane, plasma membrane G-protein coupled receptor activity Human GPR115 GDB UniProtKB {GO:0007186=PMID:15203201, GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0007218=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q8IZF3 Probable G-protein coupled receptor 115 protein 20050506 {GO:0007186=TAS, GO:0005886=IEA, GO:0004930=IEA, GO:0007218=IEA, GO:0016021=IEA} G-protein coupled receptor signaling pathway, neuropeptide signaling pathway integral to membrane, plasma membrane G-protein coupled receptor activity Human GPR119 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0031210=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0030073=GO_REF:0000019} Q8TDV5 Glucose-dependent insulinotropic receptor protein 20130413 {GO:0005886=IEA, GO:0004930=IEA, GO:0031210=IEA, GO:0016021=IEA, GO:0030073=IEA} insulin secretion integral to membrane, plasma membrane G-protein coupled receptor activity, phosphatidylcholine binding Human UniProtKB-SubCell:SL-0039 GPR12 PINC UniProtKB {GO:0007186=PMID:8530049, GO:0005887=PMID:8530049, GO:0004930=GO_REF:0000037, GO:0006874=GO_REF:0000019, GO:0031210=GO_REF:0000019} P47775 G-protein coupled receptor 12 protein 20030904 {GO:0007186=TAS, GO:0005887=TAS, GO:0004930=IEA, GO:0006874=IEA, GO:0031210=IEA} G-protein coupled receptor signaling pathway, cellular calcium ion homeostasis integral to plasma membrane G-protein coupled receptor activity, phosphatidylcholine binding Human GPR124 GDB UniProtKB {GO:0007186=PMID:15203201, GO:0005886=GO_REF:0000039, GO:0050920=GO_REF:0000024, GO:0043542=GO_REF:0000024, GO:0004930=GO_REF:0000037, GO:0007218=GO_REF:0000002, GO:0045765=GO_REF:0000024, GO:0002040=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0007417=GO_REF:0000024} Q96PE1 G-protein coupled receptor 124 protein 20050504 {GO:0007186=TAS, GO:0005886=IEA, GO:0050920=ISS, GO:0043542=ISS, GO:0004930=IEA, GO:0007218=IEA, GO:0045765=ISS, GO:0002040=ISS, GO:0016021=IEA, GO:0007417=ISS} G-protein coupled receptor signaling pathway, central nervous system development, endothelial cell migration, neuropeptide signaling pathway, regulation of angiogenesis, regulation of chemotaxis, sprouting angiogenesis integral to membrane, plasma membrane G-protein coupled receptor activity Human GPR125 GDB UniProtKB {GO:0007186=PMID:15203201, GO:0004930=GO_REF:0000037, GO:0007218=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0009897=GO_REF:0000019} Q8IWK6 Probable G-protein coupled receptor 125 protein 20050504 {GO:0007186=TAS, GO:0004930=IEA, GO:0007218=IEA, GO:0016021=IEA, GO:0009897=IEA} G-protein coupled receptor signaling pathway, neuropeptide signaling pathway external side of plasma membrane, integral to membrane G-protein coupled receptor activity Human GPR126 GDB UniProtKB {GO:0007186=PMID:15203201, GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0007218=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q86SQ4 G-protein coupled receptor 126 protein 20050510 {GO:0007186=TAS, GO:0005886=IEA, GO:0004930=IEA, GO:0007218=IEA, GO:0016021=IEA} G-protein coupled receptor signaling pathway, neuropeptide signaling pathway integral to membrane, plasma membrane G-protein coupled receptor activity Human GPR135 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q8IZ08 Probable G-protein coupled receptor 135 protein 20130413 {GO:0005886=IEA, GO:0004930=IEA, GO:0016021=IEA} integral to membrane, plasma membrane G-protein coupled receptor activity Human UniProtKB-SubCell:SL-0039 GPR142 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0030054=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q7Z601 Probable G-protein coupled receptor 142 protein 20101115 {GO:0005737=IDA, GO:0030054=IDA, GO:0005886=IDA, GO:0004930=IEA, GO:0016021=IEA} cell junction, cytoplasm, integral to membrane, plasma membrane G-protein coupled receptor activity Human GPR143 PINC UniProtKB {GO:0005515=PMID:19717472, GO:0033162=PMID:16621890, GO:0072544=PMID:18828673, GO:0072545=PMID:18828673, GO:0035584=PMID:18828673, GO:0006726=PMID:7647783, GO:0005886=PMID:16524428, GO:0032438=PMID:19717472, GO:0032400=PMID:19717472, GO:0005765=PMID:16621890, GO:0032402=PMID:19717472, GO:0016324=PMID:18828673, GO:0005737=PMID:10471510, GO:0050848=PMID:18828673, GO:0042470=PMID:10471510, GO:0005794=PMID:19717472, GO:0004930=PMID:16524428, GO:0048015=PMID:16524428, GO:0035240=PMID:18828673, GO:0007165=PMID:10471510, GO:0007186=PMID:16524428, GO:0016020=PMID:10471510, GO:0016021=GO_REF:0000037, GO:0035643=PMID:18828673, GO:0007601=PMID:7647783} P51810 G-protein coupled receptor 143 protein 20030904 {GO:0005515=IPI, GO:0033162=IDA, GO:0072544=IDA, GO:0072545=IDA, GO:0035584=IDA, GO:0006726=TAS, GO:0005886=IDA, GO:0032438=IMP, GO:0032400=IDA, GO:0005765=IDA, GO:0032402=IDA, GO:0016324=IDA, GO:0005737=TAS, GO:0050848=IDA, GO:0042470=IDA, GO:0005794=IDA, GO:0004930=IDA, GO:0048015=IDA, GO:0035240=IDA, GO:0007165=TAS, GO:0007186=IDA, GO:0016020=TAS, GO:0016021=IEA, GO:0035643=IDA, GO:0007601=TAS} G-protein coupled receptor signaling pathway, calcium-mediated signaling using intracellular calcium source, eye pigment biosynthetic process, melanosome localization, melanosome organization, melanosome transport, phosphatidylinositol-mediated signaling, regulation of calcium-mediated signaling, signal transduction, visual perception Golgi apparatus, apical plasma membrane, cytoplasm, integral to membrane, lysosomal membrane, melanosome, melanosome membrane, membrane, plasma membrane G-protein coupled receptor activity, L-DOPA binding, L-DOPA receptor activity, dopamine binding, protein binding, tyrosine binding Human GPR15 PINC UniProtKB {GO:0007186=PMID:8838812, GO:0004930=PMID:8838812, GO:0005887=PMID:8838812, GO:0045028=GO_REF:0000002} P49685 G-protein coupled receptor 15 protein 20030904 {GO:0007186=TAS, GO:0004930=TAS, GO:0005887=TAS, GO:0045028=IEA} G-protein coupled receptor signaling pathway integral to plasma membrane G-protein coupled purinergic nucleotide receptor activity, G-protein coupled receptor activity Human GPR151 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q8TDV0 Probable G-protein coupled receptor 151 protein 20130413 {GO:0005886=IEA, GO:0004930=IEA, GO:0016021=IEA} integral to membrane, plasma membrane G-protein coupled receptor activity Human UniProtKB-SubCell:SL-0039 GPR153 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q6NV75 Probable G-protein coupled receptor 153 protein 20130413 {GO:0005886=IEA, GO:0004930=IEA, GO:0016021=IEA} integral to membrane, plasma membrane G-protein coupled receptor activity Human UniProtKB-SubCell:SL-0039 GPR155 UniProtKB UniProtKB {GO:0035556=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0055085=GO_REF:0000002} Q7Z3F1 Integral membrane protein GPR155 protein 20130413 {GO:0035556=IEA, GO:0016021=IEA, GO:0055085=IEA} intracellular signal transduction, transmembrane transport integral to membrane Human UniProtKB-KW:KW-0812 GPR158 UniProtKB UniProtKB {GO:0008277=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0072659=GO_REF:0000019} Q5T848 Probable G-protein coupled receptor 158 protein 20130413 {GO:0008277=IEA, GO:0005886=IEA, GO:0004930=IEA, GO:0016021=IEA, GO:0072659=IEA} protein localization to plasma membrane, regulation of G-protein coupled receptor protein signaling pathway integral to membrane, plasma membrane G-protein coupled receptor activity Human UniProtKB-SubCell:SL-0039 GPR161 UniProtKB UniProtKB {GO:1901621=GO_REF:0000024, GO:0060170=GO_REF:0000039, GO:0007186=GO_REF:0000024, GO:0004930=GO_REF:0000024, GO:0030819=GO_REF:0000024, GO:0007275=GO_REF:0000037, GO:0072372=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0055037=GO_REF:0000024} Q8N6U8 G-protein coupled receptor 161 protein 20130222 {GO:1901621=ISS, GO:0060170=IEA, GO:0007186=ISS, GO:0004930=ISS, GO:0030819=ISS, GO:0007275=IEA, GO:0072372=ISS, GO:0016021=IEA, GO:0055037=ISS} G-protein coupled receptor signaling pathway, multicellular organismal development, negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning, positive regulation of cAMP biosynthetic process cilium membrane, integral to membrane, primary cilium, recycling endosome G-protein coupled receptor activity Human UniProtKB:B2RPY5 GPR17 GOC UniProtKB {GO:0070098=PMID:8558062, GO:0005886=Reactome:REACT_22436, GO:0007186=PMID:8558062, GO:0005887=PMID:8558062, GO:0045028=GO_REF:0000002, GO:0004930=GO_REF:0000002, GO:0004950=PMID:8558062, GO:0016021=GO_REF:0000002} Q13304 Uracil nucleotide/cysteinyl leukotriene receptor protein 20130413 {GO:0070098=TAS, GO:0005886=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0045028=IEA, GO:0004930=IEA, GO:0004950=TAS, GO:0016021=IEA} G-protein coupled receptor signaling pathway, chemokine-mediated signaling pathway integral to membrane, integral to plasma membrane, plasma membrane G-protein coupled purinergic nucleotide receptor activity, G-protein coupled receptor activity, chemokine receptor activity Human GPR176 PINC UniProtKB {GO:0007186=PMID:7893747, GO:0005887=PMID:7893747, GO:0004930=GO_REF:0000037, GO:0007268=PMID:7893747, GO:0016021=GO_REF:0000002} Q14439 Probable G-protein coupled receptor 176 protein 20030904 {GO:0007186=TAS, GO:0005887=TAS, GO:0004930=IEA, GO:0007268=TAS, GO:0016021=IEA} G-protein coupled receptor signaling pathway, synaptic transmission integral to membrane, integral to plasma membrane G-protein coupled receptor activity Human GPR179 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0044292=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007601=PMID:22325362, GO:0072659=GO_REF:0000019} Q6PRD1 Probable G-protein coupled receptor 179 protein 20120510 {GO:0005886=IEA, GO:0004930=IEA, GO:0044292=IEA, GO:0016021=IEA, GO:0007601=IMP, GO:0072659=IEA} protein localization to plasma membrane, visual perception dendrite terminus, integral to membrane, plasma membrane G-protein coupled receptor activity Human GPR180 UniProtKB UniProtKB {GO:0007186=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0019236=GO_REF:0000002} Q86V85 Integral membrane protein GPR180 protein 20130413 {GO:0007186=IEA, GO:0016021=IEA, GO:0019236=IEA} G-protein coupled receptor signaling pathway, response to pheromone integral to membrane Human UniProtKB-KW:KW-0812 GPR182 PINC UniProtKB {GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0007166=PMID:9367907, GO:0004888=PMID:9367907} O15218 G-protein coupled receptor 182 protein 20030904 {GO:0005886=IEA, GO:0004930=IEA, GO:0016021=IEA, GO:0007166=TAS, GO:0004888=TAS} cell surface receptor signaling pathway integral to membrane, plasma membrane G-protein coupled receptor activity, transmembrane signaling receptor activity Human GPR183 PINC UniProtKB {GO:0006955=PMID:8383238, GO:0008142=PMID:21796212, GO:0007186=PMID:21673108, GO:0005886=PMID:21673108, GO:0005887=PMID:8383238, GO:0004930=PMID:8383238, GO:0030890=PMID:21673108, GO:0045028=GO_REF:0000002, GO:0006959=GO_REF:0000024, GO:0070374=PMID:21673108, GO:0002313=GO_REF:0000024} P32249 G-protein coupled receptor 183 protein 20030904 {GO:0006955=TAS, GO:0008142=IDA, GO:0007186=IDA, GO:0005886=IDA, GO:0005887=TAS, GO:0004930=TAS, GO:0030890=IDA, GO:0045028=IEA, GO:0006959=ISS, GO:0070374=IDA, GO:0002313=ISS} G-protein coupled receptor signaling pathway, humoral immune response, immune response, mature B cell differentiation involved in immune response, positive regulation of B cell proliferation, positive regulation of ERK1 and ERK2 cascade integral to plasma membrane, plasma membrane G-protein coupled purinergic nucleotide receptor activity, G-protein coupled receptor activity, oxysterol binding Human GPR20 UniProtKB UniProtKB {GO:0007186=PMID:9073069, GO:0004930=PMID:18347022, GO:0005887=PMID:18347022} Q99678 G-protein coupled receptor 20 protein 20091202 {GO:0007186=IDA, GO:0004930=IDA, GO:0005887=IDA} G-protein coupled receptor signaling pathway integral to plasma membrane G-protein coupled receptor activity Human GPR21 PINC UniProtKB {GO:0007186=PMID:9073069, GO:0005887=PMID:9073069, GO:0004930=GO_REF:0000037} Q99679 Probable G-protein coupled receptor 21 protein 20030904 {GO:0007186=TAS, GO:0005887=TAS, GO:0004930=IEA} G-protein coupled receptor signaling pathway integral to plasma membrane G-protein coupled receptor activity Human GPR22 PINC UniProtKB {GO:0007186=PMID:9073069, GO:0005887=PMID:9073069, GO:0004930=GO_REF:0000037} Q99680 Probable G-protein coupled receptor 22 protein 20030904 {GO:0007186=TAS, GO:0005887=TAS, GO:0004930=IEA} G-protein coupled receptor signaling pathway integral to plasma membrane G-protein coupled receptor activity Human GPR25 PINC UniProtKB {GO:0007186=PMID:9020062, GO:0005887=PMID:9020062, GO:0004930=GO_REF:0000037} O00155 Probable G-protein coupled receptor 25 protein 20030904 {GO:0007186=TAS, GO:0005887=TAS, GO:0004930=IEA} G-protein coupled receptor signaling pathway integral to plasma membrane G-protein coupled receptor activity Human GPR26 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0004930=PMID:17363172, GO:0007189=PMID:17363172, GO:0016021=GO_REF:0000037} Q8NDV2 G-protein coupled receptor 26 protein 20100201 {GO:0005886=IEA, GO:0004930=IDA, GO:0007189=IDA, GO:0016021=IEA} adenylate cyclase-activating G-protein coupled receptor signaling pathway integral to membrane, plasma membrane G-protein coupled receptor activity Human GPR3 PINC UniProtKB {GO:0040020=GO_REF:0000019, GO:0005887=PMID:7639700, GO:0004930=GO_REF:0000037, GO:0007189=PMID:7639700} P46089 G-protein coupled receptor 3 protein 20030904 {GO:0040020=IEA, GO:0005887=TAS, GO:0004930=IEA, GO:0007189=TAS} adenylate cyclase-activating G-protein coupled receptor signaling pathway, regulation of meiosis integral to plasma membrane G-protein coupled receptor activity Human GPR37 PINC UniProtKB {GO:0007186=PMID:9144577, GO:0005887=PMID:9144577, GO:0004930=GO_REF:0000037, GO:0005789=GO_REF:0000039} O15354 Probable G-protein coupled receptor 37 protein 20030904 {GO:0007186=TAS, GO:0005887=TAS, GO:0004930=IEA, GO:0005789=IEA} G-protein coupled receptor signaling pathway endoplasmic reticulum membrane, integral to plasma membrane G-protein coupled receptor activity Human GPR37L1 IntAct UniProtKB {GO:0005515=PMID:20517885, GO:0008150=GO_REF:0000015, GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0016021=PMID:9539149} O60883 Endothelin B receptor-like protein 2 protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0005886=IEA, GO:0004930=IEA, GO:0016021=NAS} biological_process integral to membrane, plasma membrane G-protein coupled receptor activity, protein binding Human UniProtKB:P42785 GPR39 Reactome UniProtKB {GO:0005886=Reactome:REACT_22251, GO:0007186=PMID:9441746, GO:0005887=PMID:9441746, GO:0004930=GO_REF:0000037, GO:0046872=GO_REF:0000037} O43194 G-protein coupled receptor 39 protein 20091019 {GO:0005886=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0004930=IEA, GO:0046872=IEA} G-protein coupled receptor signaling pathway integral to plasma membrane, plasma membrane G-protein coupled receptor activity, metal ion binding Human GPR45 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q9Y5Y3 Probable G-protein coupled receptor 45 protein 20130413 {GO:0005886=IEA, GO:0004930=IEA, GO:0016021=IEA} integral to membrane, plasma membrane G-protein coupled receptor activity Human UniProtKB-SubCell:SL-0039 GPR50 PINC UniProtKB {GO:0007186=PMID:8647286, GO:0005887=PMID:8647286, GO:0004930=PMID:8647286, GO:0007267=PMID:8647286, GO:0008502=GO_REF:0000002} Q13585 Melatonin-related receptor protein 20030904 {GO:0007186=TAS, GO:0005887=TAS, GO:0004930=TAS, GO:0007267=TAS, GO:0008502=IEA} G-protein coupled receptor signaling pathway, cell-cell signaling integral to plasma membrane G-protein coupled receptor activity, melatonin receptor activity Human GPR52 PINC UniProtKB {GO:0007186=PMID:9931487, GO:0005887=PMID:9931487, GO:0004930=GO_REF:0000037} Q9Y2T5 Probable G-protein coupled receptor 52 protein 20030904 {GO:0007186=TAS, GO:0005887=TAS, GO:0004930=IEA} G-protein coupled receptor signaling pathway integral to plasma membrane G-protein coupled receptor activity Human GPR56 GDB UniProtKB {GO:0007186=PMID:15004227, GO:0005886=GO_REF:0000038, GO:0007420=PMID:15044805, GO:0005887=PMID:10049584, GO:0007218=GO_REF:0000002, GO:0004930=GO_REF:0000037, GO:0007267=PMID:10049584, GO:0016021=PMID:15004227, GO:0007155=PMID:15674329} Q9Y653 G-protein coupled receptor 56 protein 20050510 {GO:0007186=TAS, GO:0005886=IEA, GO:0007420=IMP, GO:0005887=TAS, GO:0007218=IEA, GO:0004930=IEA, GO:0007267=TAS, GO:0016021=TAS, GO:0007155=IDA} G-protein coupled receptor signaling pathway, brain development, cell adhesion, cell-cell signaling, neuropeptide signaling pathway integral to membrane, integral to plasma membrane, plasma membrane G-protein coupled receptor activity Human GPR61 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} Q9BZJ8 Probable G-protein coupled receptor 61 protein 20061026 {GO:0008150=ND, GO:0005886=IEA, GO:0004930=IEA, GO:0005575=ND, GO:0016021=IEA} biological_process cellular_component, integral to membrane, plasma membrane G-protein coupled receptor activity Human GPR63 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0016020=GO_REF:0000029, GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q9BZJ6 Probable G-protein coupled receptor 63 protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0016020=NAS, GO:0005886=IEA, GO:0004930=IEA, GO:0016021=IEA} biological_process integral to membrane, membrane, plasma membrane G-protein coupled receptor activity, molecular_function Human GPR64 HPA UniProtKB {GO:0016324=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0007186=PMID:9150425, GO:0005886=GO_REF:0000038, GO:0005887=PMID:9150425, GO:0007218=GO_REF:0000002, GO:0004930=GO_REF:0000037, GO:0007283=PMID:9150425, GO:0016021=PMID:12420295} Q8IZP9 G-protein coupled receptor 64 protein 20100326 {GO:0016324=IEA, GO:0005737=IDA, GO:0007186=TAS, GO:0005886=IEA, GO:0005887=TAS, GO:0007218=IEA, GO:0004930=IEA, GO:0007283=TAS, GO:0016021=TAS} G-protein coupled receptor signaling pathway, neuropeptide signaling pathway, spermatogenesis apical plasma membrane, cytoplasm, integral to membrane, integral to plasma membrane, plasma membrane G-protein coupled receptor activity Human GPR78 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0004930=PMID:17363172, GO:0007189=PMID:17363172, GO:0016021=GO_REF:0000037} Q96P69 G-protein coupled receptor 78 protein 20100201 {GO:0005886=IEA, GO:0004930=IDA, GO:0007189=IDA, GO:0016021=IEA} adenylate cyclase-activating G-protein coupled receptor signaling pathway integral to membrane, plasma membrane G-protein coupled receptor activity Human GPR89A GOC UniProtKB {GO:0007165=PMID:12761501, GO:0044070=PMID:18794847, GO:0030660=PMID:18794847, GO:0032580=PMID:18794847, GO:0004871=PMID:12761501, GO:0016021=GO_REF:0000037, GO:0043123=PMID:12761501, GO:0015031=GO_REF:0000037, GO:0008308=PMID:18794847, GO:0051452=PMID:18794847} B7ZAQ6 Golgi pH regulator A protein 20130413 {GO:0007165=IMP, GO:0044070=IDA, GO:0030660=IDA, GO:0032580=IDA, GO:0004871=IMP, GO:0016021=IEA, GO:0043123=IMP, GO:0015031=IEA, GO:0008308=IDA, GO:0051452=IDA} intracellular pH reduction, positive regulation of I-kappaB kinase/NF-kappaB cascade, protein transport, regulation of anion transport, signal transduction Golgi cisterna membrane, Golgi-associated vesicle membrane, integral to membrane signal transducer activity, voltage-gated anion channel activity Human GPR89B UniProtKB UniProtKB {GO:0005244=GO_REF:0000037, GO:0000139=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0015031=GO_REF:0000037} P0CG08 Golgi pH regulator B protein 20130413 {GO:0005244=IEA, GO:0000139=IEA, GO:0016021=IEA, GO:0015031=IEA} protein transport Golgi membrane, integral to membrane voltage-gated ion channel activity Human UniProtKB-SubCell:SL-0134 GPR89C UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} A6NKF9 Putative Golgi pH regulator C protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 GPRASP1 IntAct UniProtKB {GO:0005515=PMID:15086532, GO:0005737=GO_REF:0000039} Q5JY77 G-protein coupled receptor-associated sorting protein 1 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA} cytoplasm protein binding Human UniProtKB:P41143 GPRASP2 LIFEdb UniProtKB {GO:0005737=GO_REF:0000054, GO:0001540=GO_REF:0000019} Q96D09 G-protein coupled receptor-associated sorting protein 2 protein 20100607 {GO:0005737=IDA, GO:0001540=IEA} cytoplasm beta-amyloid binding Human GPRC5A HPA UniProtKB {GO:0007165=PMID:9857033, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005887=PMID:9857033, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000002, GO:0030659=GO_REF:0000039, GO:0043231=GO_REF:0000052} Q8NFJ5 Retinoic acid-induced protein 3 protein 20120912 {GO:0007165=TAS, GO:0005794=IDA, GO:0005886=IDA, GO:0005887=TAS, GO:0004930=IEA, GO:0016021=IEA, GO:0030659=IEA, GO:0043231=IDA} signal transduction Golgi apparatus, cytoplasmic vesicle membrane, integral to membrane, integral to plasma membrane, intracellular membrane-bounded organelle, plasma membrane G-protein coupled receptor activity Human GPRC5B HPA UniProtKB {GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0016021=GO_REF:0000037, GO:0030659=GO_REF:0000039, GO:0070062=PMID:21557262, GO:0043231=GO_REF:0000052} Q9NZH0 G-protein coupled receptor family C group 5 member B protein 20101115 {GO:0005794=IDA, GO:0005886=IEA, GO:0004930=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0016021=IEA, GO:0030659=IEA, GO:0070062=IDA, GO:0043231=IDA} Golgi apparatus, cytoplasmic vesicle membrane, extracellular vesicular exosome, integral to membrane, intracellular membrane-bounded organelle, nucleolus, nucleus, plasma membrane G-protein coupled receptor activity Human GPRC5C PINC UniProtKB {GO:0005739=GO_REF:0000019, GO:0007186=PMID:10783259, GO:0005887=PMID:10783259, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000002, GO:0030659=GO_REF:0000039} Q9NQ84 G-protein coupled receptor family C group 5 member C protein 20050308 {GO:0005739=IEA, GO:0007186=TAS, GO:0005887=TAS, GO:0004930=IEA, GO:0016021=IEA, GO:0030659=IEA} G-protein coupled receptor signaling pathway cytoplasmic vesicle membrane, integral to membrane, integral to plasma membrane, mitochondrion G-protein coupled receptor activity Human GPRIN1 UniProtKB UniProtKB {GO:0051219=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0031175=GO_REF:0000019, GO:0030426=GO_REF:0000039} Q7Z2K8 G protein-regulated inducer of neurite outgrowth 1 protein 20130413 {GO:0051219=IEA, GO:0005886=IEA, GO:0031175=IEA, GO:0030426=IEA} neuron projection development growth cone, plasma membrane phosphoprotein binding Human UniProtKB-SubCell:SL-0288 GPRIN2 null null {} null null null null {} null null null GPS1 PINC UniProtKB {GO:0000188=PMID:8943324, GO:0007049=PMID:8943324, GO:0005737=GO_REF:0000039, GO:0008180=PMID:18850735, GO:0010388=PMID:19141280, GO:0007254=PMID:8943324, GO:0005095=PMID:8943324} Q13098 COP9 signalosome complex subunit 1 protein 20030904 {GO:0000188=TAS, GO:0007049=TAS, GO:0005737=IEA, GO:0008180=IDA, GO:0010388=IDA, GO:0007254=TAS, GO:0005095=TAS} JNK cascade, cell cycle, cullin deneddylation, inactivation of MAPK activity cytoplasm, signalosome GTPase inhibitor activity Human GPS2 IntAct UniProtKB {GO:0000188=PMID:8943324, GO:0005515=PMID:22190034, GO:0007049=PMID:8943324, GO:0046329=PMID:11931768, GO:0017053=PMID:12628926, GO:0003714=PMID:11931768, GO:0007254=PMID:8943324, GO:0000122=PMID:11931768, GO:0005095=PMID:8943324} Q13227 G protein pathway suppressor 2 protein 20130415 {GO:0000188=TAS, GO:0005515=IPI, GO:0007049=TAS, GO:0046329=IDA, GO:0017053=IDA, GO:0003714=IDA, GO:0007254=TAS, GO:0000122=IDA, GO:0005095=TAS} JNK cascade, cell cycle, inactivation of MAPK activity, negative regulation of JNK cascade, negative regulation of transcription from RNA polymerase II promoter transcriptional repressor complex GTPase inhibitor activity, protein binding, transcription corepressor activity Human UniProtKB:P12504 GPSM1 HPA UniProtKB {GO:0005794=GO_REF:0000052, GO:0008277=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0000139=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005789=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0005092=GO_REF:0000002, GO:0030154=GO_REF:0000037, GO:0005829=GO_REF:0000039, GO:0007399=GO_REF:0000037} Q86YR5 G-protein-signaling modulator 1 protein 20110516 {GO:0005794=IDA, GO:0008277=IEA, GO:0005886=IEA, GO:0000139=IEA, GO:0005730=IDA, GO:0005789=IEA, GO:0005634=IDA, GO:0005092=IEA, GO:0030154=IEA, GO:0005829=IEA, GO:0007399=IEA} cell differentiation, nervous system development, regulation of G-protein coupled receptor protein signaling pathway Golgi apparatus, Golgi membrane, cytosol, endoplasmic reticulum membrane, nucleolus, nucleus, plasma membrane GDP-dissociation inhibitor activity Human GPSM2 ENSEMBL UniProtKB {GO:0005515=PMID:15537540, GO:0005737=GO_REF:0000052, GO:0008277=GO_REF:0000002, GO:0007186=PMID:8973305, GO:0005730=GO_REF:0000052, GO:0060487=GO_REF:0000019, GO:0000132=GO_REF:0000019, GO:0045177=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0005092=GO_REF:0000002, GO:0005938=GO_REF:0000039, GO:0042802=PMID:15537540} Q5T1N9 G-protein-signaling modulator 2 protein 20130413 {GO:0005515=IPI, GO:0005737=IDA, GO:0008277=IEA, GO:0007186=TAS, GO:0005730=IDA, GO:0060487=IEA, GO:0000132=IEA, GO:0045177=IEA, GO:0005634=IDA, GO:0005092=IEA, GO:0005938=IEA, GO:0042802=IPI} G-protein coupled receptor signaling pathway, establishment of mitotic spindle orientation, lung epithelial cell differentiation, regulation of G-protein coupled receptor protein signaling pathway apical part of cell, cell cortex, cytoplasm, nucleolus, nucleus GDP-dissociation inhibitor activity, identical protein binding, protein binding Human Ensembl:ENSMUSP00000029482 GPSM3 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000039, GO:0008277=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0005092=GO_REF:0000002, GO:0030695=GO_REF:0000002} Q9Y4H4 G-protein-signaling modulator 3 protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0005737=IEA, GO:0008277=IEA, GO:0005575=ND, GO:0005092=IEA, GO:0030695=IEA} biological_process, regulation of G-protein coupled receptor protein signaling pathway cellular_component, cytoplasm GDP-dissociation inhibitor activity, GTPase regulator activity, molecular_function Human GPT Reactome UniProtKB {GO:0034641=Reactome:REACT_13, GO:0006807=GO_REF:0000029, GO:0005737=GO_REF:0000029, GO:0004021=Reactome:REACT_356, GO:0042853=GO_REF:0000041, GO:0030170=GO_REF:0000002, GO:0006094=GO_REF:0000029, GO:0008652=Reactome:REACT_238, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_356} P24298 Alanine aminotransferase 1 protein 20100210 {GO:0034641=TAS, GO:0006807=NAS, GO:0005737=NAS, GO:0004021=EXP, GO:0042853=IEA, GO:0030170=IEA, GO:0006094=NAS, GO:0008652=TAS, GO:0044281=TAS, GO:0005829=TAS} L-alanine catabolic process, cellular amino acid biosynthetic process, cellular nitrogen compound metabolic process, gluconeogenesis, nitrogen compound metabolic process, small molecule metabolic process cytoplasm, cytosol L-alanine:2-oxoglutarate aminotransferase activity, pyridoxal phosphate binding Human GPT2 Reactome UniProtKB {GO:0034641=Reactome:REACT_13, GO:0004021=Reactome:REACT_21311, GO:0009058=GO_REF:0000002, GO:0042851=PMID:11863375, GO:0005759=Reactome:REACT_21311, GO:0006103=PMID:11863375, GO:0042853=GO_REF:0000041, GO:0030170=GO_REF:0000002, GO:0008652=Reactome:REACT_238, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002} Q8TD30 Alanine aminotransferase 2 protein 20130213 {GO:0034641=TAS, GO:0004021=EXP, GO:0009058=IEA, GO:0042851=IDA, GO:0005759=TAS, GO:0006103=IDA, GO:0042853=IEA, GO:0030170=IEA, GO:0008652=TAS, GO:0044281=TAS, GO:0003824=IEA} 2-oxoglutarate metabolic process, L-alanine catabolic process, L-alanine metabolic process, biosynthetic process, cellular amino acid biosynthetic process, cellular nitrogen compound metabolic process, small molecule metabolic process mitochondrial matrix L-alanine:2-oxoglutarate aminotransferase activity, catalytic activity, pyridoxal phosphate binding Human GPX1 BHF-UCL UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0042542=PMID:12829378, GO:0009650=PMID:17097614, GO:0060047=PMID:14573732, GO:0001659=GO_REF:0000019, GO:0007605=GO_REF:0000019, GO:0006749=PMID:12829378, GO:0004602=PMID:12829378, GO:0043523=GO_REF:0000019, GO:0006195=Reactome:REACT_2086, GO:0045444=GO_REF:0000019, GO:0009410=GO_REF:0000019, GO:0042744=PMID:15203190, GO:0006979=GO_REF:0000002, GO:0010332=GO_REF:0000019, GO:0033194=GO_REF:0000019, GO:0014902=GO_REF:0000019, GO:0051702=GO_REF:0000019, GO:0048741=GO_REF:0000019, GO:0009636=GO_REF:0000019, GO:0033599=PMID:16945136, GO:0043534=GO_REF:0000019, GO:0001885=GO_REF:0000019, GO:0006144=Reactome:REACT_522, GO:0006641=GO_REF:0000019, GO:0045454=PMID:12829378, GO:0051450=GO_REF:0000019, GO:0051897=GO_REF:0000019, GO:0017124=PMID:12893824, GO:0002862=GO_REF:0000019, GO:0004866=PMID:12751788, GO:0001836=PMID:12221075, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_150391, GO:0005739=PMID:10833429, GO:0005737=PMID:10833429, GO:0042311=GO_REF:0000019, GO:0018158=GO_REF:0000019, GO:0043403=GO_REF:0000019, GO:0043154=PMID:12221075, GO:0043066=PMID:12221075, GO:0019372=Reactome:REACT_150209, GO:0008631=GO_REF:0000019, GO:0060055=GO_REF:0000019, GO:0010269=PMID:12810669, GO:0055086=Reactome:REACT_1698, GO:0006917=GO_REF:0000019, GO:0061136=PMID:12751788, GO:0009609=GO_REF:0000019, GO:0040029=PMID:16132718} P07203 Glutathione peroxidase 1 protein 20071109 {GO:0019369=TAS, GO:0042542=IMP, GO:0009650=IMP, GO:0060047=IMP, GO:0001659=IEA, GO:0007605=IEA, GO:0006749=IDA, GO:0004602=IDA, GO:0043523=IEA, GO:0006195=TAS, GO:0045444=IEA, GO:0009410=IEA, GO:0042744=IDA, GO:0006979=IEA, GO:0010332=IEA, GO:0033194=IEA, GO:0014902=IEA, GO:0051702=IEA, GO:0048741=IEA, GO:0009636=IEA, GO:0033599=IMP, GO:0043534=IEA, GO:0001885=IEA, GO:0006144=TAS, GO:0006641=IEA, GO:0045454=IDA, GO:0051450=IEA, GO:0051897=IEA, GO:0017124=IPI, GO:0002862=IEA, GO:0004866=IDA, GO:0001836=IMP, GO:0044281=TAS, GO:0005829=TAS, GO:0005739=IDA, GO:0005737=IDA, GO:0042311=IEA, GO:0018158=IEA, GO:0043403=IEA, GO:0043154=IMP, GO:0043066=IMP, GO:0019372=TAS, GO:0008631=IEA, GO:0060055=IEA, GO:0010269=IMP, GO:0055086=TAS, GO:0006917=IEA, GO:0061136=IDA, GO:0009609=IEA, GO:0040029=IDA} UV protection, angiogenesis involved in wound healing, arachidonic acid metabolic process, blood vessel endothelial cell migration, cell redox homeostasis, endothelial cell development, fat cell differentiation, glutathione metabolic process, heart contraction, hydrogen peroxide catabolic process, induction of apoptosis, interaction with symbiont, intrinsic apoptotic signaling pathway in response to oxidative stress, lipoxygenase pathway, myoblast proliferation, myotube differentiation, negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of inflammatory response to antigenic stimulus, nucleobase-containing small molecule metabolic process, positive regulation of protein kinase B signaling cascade, protein oxidation, purine nucleobase metabolic process, purine nucleotide catabolic process, regulation of gene expression, epigenetic, regulation of mammary gland epithelial cell proliferation, regulation of neuron apoptotic process, regulation of proteasomal protein catabolic process, release of cytochrome c from mitochondria, response to gamma radiation, response to hydrogen peroxide, response to hydroperoxide, response to oxidative stress, response to selenium ion, response to symbiotic bacterium, response to toxic substance, response to xenobiotic stimulus, sensory perception of sound, skeletal muscle fiber development, skeletal muscle tissue regeneration, small molecule metabolic process, temperature homeostasis, triglyceride metabolic process, vasodilation cytoplasm, cytosol, mitochondrion SH3 domain binding, endopeptidase inhibitor activity, glutathione peroxidase activity Human GPX2 HPA UniProtKB {GO:0004602=GO_REF:0000003, GO:0005737=GO_REF:0000052, GO:0001659=GO_REF:0000019, GO:0002862=GO_REF:0000019, GO:0051702=GO_REF:0000019, GO:0009609=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0009055=PMID:8428933, GO:0005634=GO_REF:0000052, GO:0006979=GO_REF:0000002} P18283 Glutathione peroxidase 2 protein 20101115 {GO:0004602=IEA, GO:0005737=IDA, GO:0001659=IEA, GO:0002862=IEA, GO:0051702=IEA, GO:0009609=IEA, GO:0005730=IDA, GO:0009055=TAS, GO:0005634=IDA, GO:0006979=IEA} interaction with symbiont, negative regulation of inflammatory response to antigenic stimulus, response to oxidative stress, response to symbiotic bacterium, temperature homeostasis cytoplasm, nucleolus, nucleus electron carrier activity, glutathione peroxidase activity Human GPX4 Reactome UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0005739=PMID:9705830, GO:0004602=PMID:9705830, GO:0019372=Reactome:REACT_150209, GO:0047066=GO_REF:0000003, GO:0007275=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0006644=PMID:8039723, GO:0006979=GO_REF:0000002, GO:0005829=Reactome:REACT_150391, GO:0055114=PMID:9705830} P36969 Phospholipid hydroperoxide glutathione peroxidase, mitochondrial protein 20130301 {GO:0019369=TAS, GO:0005739=TAS, GO:0004602=TAS, GO:0019372=TAS, GO:0047066=IEA, GO:0007275=IEA, GO:0044281=TAS, GO:0006644=TAS, GO:0006979=IEA, GO:0005829=TAS, GO:0055114=TAS} arachidonic acid metabolic process, lipoxygenase pathway, multicellular organismal development, oxidation-reduction process, phospholipid metabolic process, response to oxidative stress, small molecule metabolic process cytosol, mitochondrion glutathione peroxidase activity, phospholipid-hydroperoxide glutathione peroxidase activity Human GPX7 UniProtKB UniProtKB {GO:0004602=GO_REF:0000003, GO:0005576=GO_REF:0000039, GO:0006979=GO_REF:0000002} Q96SL4 Glutathione peroxidase 7 protein 20130413 {GO:0004602=IEA, GO:0005576=IEA, GO:0006979=IEA} response to oxidative stress extracellular region glutathione peroxidase activity Human UniProtKB-SubCell:SL-0243 GPX8 UniProtKB UniProtKB {GO:0004602=GO_REF:0000003, GO:0016021=GO_REF:0000037, GO:0006979=GO_REF:0000002} Q8TED1 Probable glutathione peroxidase 8 protein 20130413 {GO:0004602=IEA, GO:0016021=IEA, GO:0006979=IEA} response to oxidative stress integral to membrane glutathione peroxidase activity Human EC:1.11.1.9 GRAMD1A UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q96CP6 GRAM domain-containing protein 1A protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 GRAMD1C UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8IYS0 GRAM domain-containing protein 1C protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 GRAMD3 UniProtKB UniProtKB {GO:0005881=PMID:23264731} Q96HH9 GRAM domain-containing protein 3 protein 20130311 {GO:0005881=IDA} cytoplasmic microtubule Human GRAMD4 UniProtKB UniProtKB {GO:0031966=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q6IC98 GRAM domain-containing protein 4 protein 20130413 {GO:0031966=IEA, GO:0006915=IEA, GO:0016021=IEA} apoptotic process integral to membrane, mitochondrial membrane Human UniProtKB-SubCell:SL-0171 GRAP Reactome UniProtKB {GO:0005737=PMID:8647802, GO:0005070=PMID:8647802, GO:0007267=PMID:8647802, GO:0007265=PMID:8647802, GO:0005829=Reactome:REACT_111192} Q13588 GRB2-related adapter protein protein 20110711 {GO:0005737=TAS, GO:0005070=TAS, GO:0007267=TAS, GO:0007265=TAS, GO:0005829=TAS} Ras protein signal transduction, cell-cell signaling cytoplasm, cytosol SH3/SH2 adaptor activity Human GRAP2 HPA UniProtKB {GO:0005515=PMID:12359715, GO:0050852=Reactome:REACT_12526, GO:0005737=GO_REF:0000052, GO:0045087=Reactome:REACT_6802, GO:0005070=PMID:9878555, GO:0031295=Reactome:REACT_19344, GO:0007267=PMID:9878555, GO:0005730=GO_REF:0000052, GO:0007265=PMID:9878555, GO:0005634=GO_REF:0000052, GO:0005829=Reactome:REACT_147838, GO:0005768=PMID:21179510} O75791 GRB2-related adapter protein 2 protein 20080205 {GO:0005515=IPI, GO:0050852=TAS, GO:0005737=IDA, GO:0045087=TAS, GO:0005070=TAS, GO:0031295=TAS, GO:0007267=TAS, GO:0005730=IDA, GO:0007265=TAS, GO:0005634=IDA, GO:0005829=TAS, GO:0005768=IDA} Ras protein signal transduction, T cell costimulation, T cell receptor signaling pathway, cell-cell signaling, innate immune response cytoplasm, cytosol, endosome, nucleolus, nucleus SH3/SH2 adaptor activity, protein binding Human GRASP UniProtKB UniProtKB {GO:0007165=GO_REF:0000019, GO:0048471=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0008104=GO_REF:0000019, GO:0030306=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0045211=GO_REF:0000039, GO:0030165=GO_REF:0000019} Q7Z6J2 General receptor for phosphoinositides 1-associated scaffold protein protein 20130413 {GO:0007165=IEA, GO:0048471=IEA, GO:0030054=IEA, GO:0008104=IEA, GO:0030306=IEA, GO:0005886=IEA, GO:0045211=IEA, GO:0030165=IEA} protein localization, signal transduction cell junction, perinuclear region of cytoplasm, plasma membrane, postsynaptic membrane ADP-ribosylation factor binding, PDZ domain binding Human UniProtKB-SubCell:SL-0198 GRB10 BHF-UCL UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005515=PMID:8798570, GO:0030949=PMID:15060076, GO:0005886=PMID:9006901, GO:0005158=PMID:15664450, GO:0046627=PMID:15664450, GO:0030178=PMID:17376403, GO:0045719=GO_REF:0000019, GO:0005829=Reactome:REACT_111192, GO:0042326=GO_REF:0000019, GO:0007165=GO_REF:0000002, GO:0005737=PMID:9006901, GO:0005543=GO_REF:0000002, GO:0005070=GO_REF:0000019, GO:0046325=PMID:15664450, GO:0048009=GO_REF:0000019, GO:0042327=GO_REF:0000019} Q13322 Growth factor receptor-bound protein 10 protein 20090430 {GO:0008286=TAS, GO:0005515=IPI, GO:0030949=IDA, GO:0005886=TAS, GO:0005158=ISS, GO:0046627=ISS, GO:0030178=IDA, GO:0045719=IEA, GO:0005829=TAS, GO:0042326=IEA, GO:0007165=IEA, GO:0005737=TAS, GO:0005543=IEA, GO:0005070=IEA, GO:0046325=ISS, GO:0048009=IEA, GO:0042327=IEA} insulin receptor signaling pathway, insulin-like growth factor receptor signaling pathway, negative regulation of Wnt receptor signaling pathway, negative regulation of glucose import, negative regulation of glycogen biosynthetic process, negative regulation of insulin receptor signaling pathway, negative regulation of phosphorylation, positive regulation of phosphorylation, positive regulation of vascular endothelial growth factor receptor signaling pathway, signal transduction cytoplasm, cytosol, plasma membrane SH3/SH2 adaptor activity, insulin receptor binding, phospholipid binding, protein binding Human UniProtKB:Q60760 GRB14 BHF-UCL UniProtKB {GO:0007165=GO_REF:0000002, GO:0005737=PMID:11278563, GO:0005543=GO_REF:0000002, GO:0005886=PMID:11278563, GO:0000139=GO_REF:0000039, GO:0007596=Reactome:REACT_604, GO:0005070=GO_REF:0000019, GO:0050900=Reactome:REACT_12051, GO:0010008=GO_REF:0000039, GO:0043231=PMID:11278563, GO:0005829=Reactome:REACT_16885} Q14449 Growth factor receptor-bound protein 14 protein 20081217 {GO:0007165=IEA, GO:0005737=IDA, GO:0005543=IEA, GO:0005886=IDA, GO:0000139=IEA, GO:0007596=TAS, GO:0005070=IEA, GO:0050900=TAS, GO:0010008=IEA, GO:0043231=IDA, GO:0005829=TAS} blood coagulation, leukocyte migration, signal transduction Golgi membrane, cytoplasm, cytosol, endosome membrane, intracellular membrane-bounded organelle, plasma membrane SH3/SH2 adaptor activity, phospholipid binding Human GRB2 BHF-UCL UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005515=PMID:22726438, GO:0017124=PMID:19509291, GO:0005154=PMID:12577067, GO:0005886=Reactome:REACT_147854, GO:0031295=Reactome:REACT_19344, GO:0060670=GO_REF:0000019, GO:0007267=PMID:8253073, GO:0005634=PMID:21179510, GO:0043560=PMID:8388384, GO:0007265=Reactome:REACT_12033, GO:0050900=Reactome:REACT_12051, GO:0051291=GO_REF:0000019, GO:0030154=GO_REF:0000019, GO:0005829=Reactome:REACT_12490, GO:0031623=PMID:14985334, GO:0005737=PMID:21179510, GO:0048646=GO_REF:0000019, GO:0030838=GO_REF:0000019, GO:0008180=PMID:22561606, GO:0007173=Reactome:REACT_9417, GO:0007411=Reactome:REACT_18266, GO:0043408=GO_REF:0000019, GO:0012506=GO_REF:0000019, GO:0070436=PMID:20086093, GO:0048011=Reactome:REACT_11061, GO:0005794=GO_REF:0000039, GO:0019901=PMID:20086093, GO:0005168=PMID:15488758, GO:0048015=Reactome:REACT_12464, GO:0019903=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0042059=Reactome:REACT_12484, GO:0030168=Reactome:REACT_798, GO:0071479=PMID:20160708, GO:0042770=PMID:20160708, GO:0046875=PMID:12925710, GO:0008543=Reactome:REACT_9470, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0005070=PMID:8253073, GO:0019048=GO_REF:0000037, GO:0001784=GO_REF:0000019, GO:2000379=PMID:20160708, GO:0038096=Reactome:REACT_160123, GO:0005768=PMID:21179510} P62993 Growth factor receptor-bound protein 2 protein 20120308 {GO:0008286=TAS, GO:0005515=IPI, GO:0017124=IDA, GO:0005154=IPI, GO:0005886=TAS, GO:0031295=TAS, GO:0060670=IEA, GO:0007267=TAS, GO:0005634=IDA, GO:0043560=IPI, GO:0007265=TAS, GO:0050900=TAS, GO:0051291=IEA, GO:0030154=IEA, GO:0005829=TAS, GO:0031623=IMP, GO:0005737=IDA, GO:0048646=IEA, GO:0030838=IEA, GO:0008180=IDA, GO:0007173=TAS, GO:0007411=TAS, GO:0043408=IEA, GO:0012506=IEA, GO:0070436=IDA, GO:0048011=TAS, GO:0005794=IEA, GO:0019901=IPI, GO:0005168=IPI, GO:0048015=TAS, GO:0019903=IEA, GO:0019904=IEA, GO:0007568=IEA, GO:0042059=TAS, GO:0030168=TAS, GO:0071479=IMP, GO:0042770=IMP, GO:0046875=IPI, GO:0008543=TAS, GO:0007596=TAS, GO:0045087=TAS, GO:0005070=TAS, GO:0019048=IEA, GO:0001784=IEA, GO:2000379=IMP, GO:0038096=TAS, GO:0005768=IDA} Fc-gamma receptor signaling pathway involved in phagocytosis, Ras protein signal transduction, T cell costimulation, aging, anatomical structure formation involved in morphogenesis, axon guidance, blood coagulation, branching involved in labyrinthine layer morphogenesis, cell differentiation, cell-cell signaling, cellular response to ionizing radiation, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, leukocyte migration, negative regulation of epidermal growth factor receptor signaling pathway, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, platelet activation, positive regulation of actin filament polymerization, positive regulation of reactive oxygen species metabolic process, protein heterooligomerization, receptor internalization, regulation of MAPK cascade, signal transduction in response to DNA damage, virus-host interaction Golgi apparatus, Grb2-EGFR complex, cytoplasm, cytosol, endosome, nucleus, plasma membrane, signalosome, vesicle membrane SH3 domain binding, SH3/SH2 adaptor activity, ephrin receptor binding, epidermal growth factor receptor binding, insulin receptor substrate binding, neurotrophin TRKA receptor binding, phosphotyrosine binding, protein binding, protein domain specific binding, protein kinase binding, protein phosphatase binding Human GRB7 IntAct UniProtKB {GO:0005515=PMID:20665473, GO:0017148=GO_REF:0000024, GO:0030335=PMID:12021278, GO:0005886=GO_REF:0000039, GO:0019901=PMID:12021278, GO:0010494=GO_REF:0000024, GO:0003723=GO_REF:0000037, GO:0042995=GO_REF:0000039, GO:0050900=Reactome:REACT_12051, GO:0042802=PMID:15841400, GO:0005829=Reactome:REACT_115703, GO:0034063=GO_REF:0000024, GO:0007173=PMID:9710451, GO:0007596=Reactome:REACT_604, GO:0005070=PMID:9710451, GO:0035091=PMID:12021278, GO:0005925=PMID:12021278} Q14451 Growth factor receptor-bound protein 7 protein 20130415 {GO:0005515=IPI, GO:0017148=ISS, GO:0030335=IDA, GO:0005886=IEA, GO:0019901=IDA, GO:0010494=ISS, GO:0003723=IEA, GO:0042995=IEA, GO:0050900=TAS, GO:0042802=IPI, GO:0005829=TAS, GO:0034063=ISS, GO:0007173=TAS, GO:0007596=TAS, GO:0005070=TAS, GO:0035091=IDA, GO:0005925=IDA} blood coagulation, epidermal growth factor receptor signaling pathway, leukocyte migration, negative regulation of translation, positive regulation of cell migration, stress granule assembly cell projection, cytoplasmic stress granule, cytosol, focal adhesion, plasma membrane RNA binding, SH3/SH2 adaptor activity, identical protein binding, phosphatidylinositol binding, protein binding, protein kinase binding Human UniProtKB:Q14451 GREM1 BHF-UCL UniProtKB {GO:0005515=PMID:16545136, GO:0042346=GO_REF:0000019, GO:0008284=PMID:16545136, GO:0030308=GO_REF:0000019, GO:0001658=GO_REF:0000019, GO:0033689=PMID:15539560, GO:0002042=PMID:9660951, GO:0007267=GO_REF:0000019, GO:0010717=PMID:16816361, GO:0009954=GO_REF:0000019, GO:0030326=GO_REF:0000019, GO:0032872=PMID:9660951, GO:0060394=PMID:15539560, GO:0051893=GO_REF:0000019, GO:0060676=GO_REF:0000019, GO:0005615=PMID:9660951, GO:0051973=PMID:16545136, GO:0030514=PMID:15539560, GO:0016015=PMID:9660951, GO:0030296=GO_REF:0000019, GO:0051092=GO_REF:0000019, GO:0036122=PMID:9660951, GO:0045944=PMID:9660951, GO:0030199=PMID:15539560, GO:0090191=GO_REF:0000019, GO:0090090=PMID:15539560, GO:0048018=PMID:9660951, GO:0090190=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0006915=GO_REF:0000019, GO:0090291=PMID:15539560, GO:0030502=PMID:15539560, GO:0005125=GO_REF:0000037, GO:0045766=GO_REF:0000019, GO:2000727=PMID:9660951, GO:0000902=PMID:16545136, GO:0046851=PMID:15539560, GO:0003337=GO_REF:0000019, GO:0072331=PMID:9660951, GO:1900155=PMID:15539560, GO:0048263=PMID:9660951, GO:0043184=PMID:9660951, GO:1900158=PMID:15539560, GO:0090027=GO_REF:0000024, GO:0045892=GO_REF:0000019, GO:0003257=PMID:9660951} O60565 Gremlin-1 protein 20120319 {GO:0005515=IPI, GO:0042346=IEA, GO:0008284=IDA, GO:0030308=IEA, GO:0001658=IEA, GO:0033689=IMP, GO:0002042=ISS, GO:0007267=IEA, GO:0010717=IMP, GO:0009954=IEA, GO:0030326=IEA, GO:0032872=ISS, GO:0060394=IDA, GO:0051893=IEA, GO:0060676=IEA, GO:0005615=NAS, GO:0051973=IDA, GO:0030514=IDA, GO:0016015=ISS, GO:0030296=IEA, GO:0051092=IEA, GO:0036122=ISS, GO:0045944=ISS, GO:0030199=IMP, GO:0090191=IEA, GO:0090090=IDA, GO:0048018=ISS, GO:0090190=IEA, GO:0009986=IEA, GO:0006915=IEA, GO:0090291=IMP, GO:0030502=IMP, GO:0005125=IEA, GO:0045766=IEA, GO:2000727=ISS, GO:0000902=IDA, GO:0046851=IMP, GO:0003337=IEA, GO:0072331=ISS, GO:1900155=IMP, GO:0048263=IMP, GO:0043184=ISS, GO:1900158=IMP, GO:0090027=ISS, GO:0045892=IEA, GO:0003257=ISS} apoptotic process, branching involved in ureteric bud morphogenesis, cell migration involved in sprouting angiogenesis, cell morphogenesis, cell-cell signaling, collagen fibril organization, determination of dorsal identity, embryonic limb morphogenesis, mesenchymal to epithelial transition involved in metanephros morphogenesis, negative regulation of BMP signaling pathway, negative regulation of bone mineralization, negative regulation of bone mineralization involved in bone maturation, negative regulation of bone remodeling, negative regulation of bone trabecula formation, negative regulation of branching involved in ureteric bud morphogenesis, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cell growth, negative regulation of monocyte chemotaxis, negative regulation of osteoblast proliferation, negative regulation of osteoclast proliferation, negative regulation of pathway-restricted SMAD protein phosphorylation, negative regulation of transcription, DNA-dependent, positive regulation of NF-kappaB import into nucleus, positive regulation of NF-kappaB transcription factor activity, positive regulation of angiogenesis, positive regulation of branching involved in ureteric bud morphogenesis, positive regulation of cardiac muscle cell differentiation, positive regulation of cell proliferation, positive regulation of telomerase activity, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation, proximal/distal pattern formation, regulation of epithelial to mesenchymal transition, regulation of focal adhesion assembly, regulation of stress-activated MAPK cascade, signal transduction by p53 class mediator, ureteric bud formation cell surface, extracellular space BMP binding, cytokine activity, morphogen activity, protein binding, protein tyrosine kinase activator activity, receptor agonist activity, vascular endothelial growth factor receptor 2 binding Human UniProtKB:O70326 GREM2 Reactome UniProtKB {GO:0005576=Reactome:REACT_12026, GO:0030509=Reactome:REACT_12034, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037} Q9H772 Gremlin-2 protein 20130301 {GO:0005576=TAS, GO:0030509=TAS, GO:0005615=IEA, GO:0005125=IEA} BMP signaling pathway extracellular region, extracellular space cytokine activity Human GRHL1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0005794=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005654=Reactome:REACT_115770, GO:0007275=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0003677=GO_REF:0000037, GO:0044255=Reactome:REACT_22279, GO:0006351=GO_REF:0000037} Q9NZI5 Grainyhead-like protein 1 homolog protein 20080205 {GO:0005737=IDA, GO:0006355=IEA, GO:0005794=IDA, GO:0005634=IDA, GO:0005654=TAS, GO:0007275=IEA, GO:0044281=TAS, GO:0003677=IEA, GO:0044255=TAS, GO:0006351=IEA} cellular lipid metabolic process, multicellular organismal development, regulation of transcription, DNA-dependent, small molecule metabolic process, transcription, DNA-dependent Golgi apparatus, cytoplasm, nucleoplasm, nucleus DNA binding Human GRHL2 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0001843=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0001701=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6ISB3 Grainyhead-like protein 2 homolog protein 20101115 {GO:0005737=IDA, GO:0006355=IEA, GO:0005730=IDA, GO:0001843=IEA, GO:0005634=IDA, GO:0001701=IEA, GO:0003677=IEA, GO:0006351=IEA} in utero embryonic development, neural tube closure, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleolus, nucleus DNA binding Human GRHL3 MGI UniProtKB {GO:0001736=GO_REF:0000019, GO:0007389=GO_REF:0000019, GO:0000981=GO_REF:0000019, GO:0090179=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0007398=GO_REF:0000019, GO:0007417=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0008544=GO_REF:0000019, GO:0032321=GO_REF:0000019, GO:0032956=PMID:20643356, GO:0045944=GO_REF:0000019, GO:0061029=GO_REF:0000019, GO:0042060=GO_REF:0000019, GO:0090103=GO_REF:0000019} Q8TE85 Grainyhead-like protein 3 homolog protein 20101206 {GO:0001736=IEA, GO:0007389=IEA, GO:0000981=IEA, GO:0090179=IEA, GO:0005634=IEA, GO:0007398=IEA, GO:0007417=IEA, GO:0003677=IEA, GO:0008544=IEA, GO:0032321=IEA, GO:0032956=IGI, GO:0045944=IEA, GO:0061029=IEA, GO:0042060=IEA, GO:0090103=IEA} central nervous system development, cochlea morphogenesis, ectoderm development, epidermis development, establishment of planar polarity, eyelid development in camera-type eye, pattern specification process, planar cell polarity pathway involved in neural tube closure, positive regulation of Rho GTPase activity, positive regulation of transcription from RNA polymerase II promoter, regulation of actin cytoskeleton organization, wound healing nucleus DNA binding, sequence-specific DNA binding RNA polymerase II transcription factor activity Human UniProtKB:Q8IW93 GRHPR LIFEdb UniProtKB {GO:0007588=PMID:10484776, GO:0048037=GO_REF:0000002, GO:0005782=Reactome:REACT_16910, GO:0008465=PMID:10484776, GO:0044281=Reactome:REACT_111217, GO:0016618=PMID:17510093, GO:0051259=PMID:16756993, GO:0070402=PMID:16756993, GO:0042803=PMID:16756993, GO:0016616=GO_REF:0000002, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000054, GO:0051287=PMID:10484776, GO:0008152=PMID:10524214, GO:0046487=Reactome:REACT_16925, GO:0030267=PMID:10484776, GO:0055114=PMID:10484776} Q9UBQ7 Glyoxylate reductase/hydroxypyruvate reductase protein 20100607 {GO:0007588=IMP, GO:0048037=IEA, GO:0005782=TAS, GO:0008465=IDA, GO:0044281=TAS, GO:0016618=IDA, GO:0051259=IDA, GO:0070402=IDA, GO:0042803=IDA, GO:0016616=IEA, GO:0034641=TAS, GO:0005737=IDA, GO:0051287=TAS, GO:0008152=NAS, GO:0046487=TAS, GO:0030267=IDA, GO:0055114=IDA} cellular nitrogen compound metabolic process, excretion, glyoxylate metabolic process, metabolic process, oxidation-reduction process, protein oligomerization, small molecule metabolic process cytoplasm, peroxisomal matrix NAD binding, NADPH binding, cofactor binding, glycerate dehydrogenase activity, glyoxylate reductase (NADP) activity, hydroxypyruvate reductase activity, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, protein homodimerization activity Human GRIA1 BHF-UCL UniProtKB {GO:0005515=PMID:20805473, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_20569, GO:0005234=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0030425=GO_REF:0000024, GO:0031623=GO_REF:0000019, GO:0043197=GO_REF:0000024, GO:0045211=GO_REF:0000039, GO:0004971=PMID:20805473, GO:0032281=GO_REF:0000024, GO:0004970=GO_REF:0000002, GO:0015277=PMID:1311100, GO:0043025=GO_REF:0000024, GO:0007616=GO_REF:0000019, GO:0009986=GO_REF:0000024, GO:0014069=GO_REF:0000024, GO:0030165=GO_REF:0000024, GO:0044309=GO_REF:0000024, GO:0030666=Reactome:REACT_18330, GO:0007165=PMID:1311100, GO:0032590=GO_REF:0000019, GO:0030288=GO_REF:0000002, GO:0008066=PMID:1320959, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000038} P42261 Glutamate receptor 1 protein 20110218 {GO:0005515=IPI, GO:0030054=IEA, GO:0005886=TAS, GO:0005234=IEA, GO:0007268=TAS, GO:0030425=ISS, GO:0031623=IEA, GO:0043197=ISS, GO:0045211=IEA, GO:0004971=IDA, GO:0032281=ISS, GO:0004970=IEA, GO:0015277=TAS, GO:0043025=ISS, GO:0007616=IEA, GO:0009986=ISS, GO:0014069=ISS, GO:0030165=ISS, GO:0044309=ISS, GO:0030666=TAS, GO:0007165=TAS, GO:0032590=IEA, GO:0030288=IEA, GO:0008066=TAS, GO:0005789=IEA, GO:0016021=IEA} long-term memory, receptor internalization, signal transduction, synaptic transmission alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex, cell junction, cell surface, dendrite, dendrite membrane, dendritic spine, endocytic vesicle membrane, endoplasmic reticulum membrane, integral to membrane, neuron spine, neuronal cell body, outer membrane-bounded periplasmic space, plasma membrane, postsynaptic density, postsynaptic membrane PDZ domain binding, alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity, extracellular-glutamate-gated ion channel activity, glutamate receptor activity, ionotropic glutamate receptor activity, kainate selective glutamate receptor activity, protein binding Human UniProtKB:P23818 GRIA2 Reactome UniProtKB {GO:0005215=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_20569, GO:0005234=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0030666=Reactome:REACT_18330, GO:0007165=PMID:8003671, GO:0035235=PMID:20614889, GO:0005887=GO_REF:0000024, GO:0004971=GO_REF:0000024, GO:0045211=GO_REF:0000039, GO:0030288=GO_REF:0000002, GO:0004970=PMID:20614889, GO:0032281=GO_REF:0000024, GO:0008066=PMID:1311100, GO:0005789=GO_REF:0000039, GO:0015277=GO_REF:0000024, GO:0016021=GO_REF:0000038} P42262 Glutamate receptor 2 protein 20130129 {GO:0005215=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0005234=IEA, GO:0007268=TAS, GO:0030666=TAS, GO:0007165=TAS, GO:0035235=IDA, GO:0005887=ISS, GO:0004971=ISS, GO:0045211=IEA, GO:0030288=IEA, GO:0004970=IDA, GO:0032281=ISS, GO:0008066=TAS, GO:0005789=IEA, GO:0015277=ISS, GO:0016021=IEA} ionotropic glutamate receptor signaling pathway, signal transduction, synaptic transmission alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex, cell junction, endocytic vesicle membrane, endoplasmic reticulum membrane, integral to membrane, integral to plasma membrane, outer membrane-bounded periplasmic space, plasma membrane, postsynaptic membrane alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity, extracellular-glutamate-gated ion channel activity, glutamate receptor activity, ionotropic glutamate receptor activity, kainate selective glutamate receptor activity, transporter activity Human GRIA3 Reactome UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_20569, GO:0005234=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0007215=PMID:1709304, GO:0030666=Reactome:REACT_18393, GO:0016020=GO_REF:0000002, GO:0045211=GO_REF:0000039, GO:0004971=PMID:21172611, GO:0004970=GO_REF:0000002, GO:0032281=GO_REF:0000024, GO:0006810=PMID:1709304, GO:0016021=GO_REF:0000038} P42263 Glutamate receptor 3 protein 20130129 {GO:0030054=IEA, GO:0005886=TAS, GO:0005234=IEA, GO:0007268=TAS, GO:0007215=TAS, GO:0030666=TAS, GO:0016020=IEA, GO:0045211=IEA, GO:0004971=IDA, GO:0004970=IEA, GO:0032281=ISS, GO:0006810=TAS, GO:0016021=IEA} glutamate receptor signaling pathway, synaptic transmission, transport alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex, cell junction, endocytic vesicle membrane, integral to membrane, membrane, plasma membrane, postsynaptic membrane alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity, extracellular-glutamate-gated ion channel activity, ionotropic glutamate receptor activity Human GRIA4 GOC UniProtKB {GO:0005215=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_20569, GO:0005234=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0007215=PMID:8589990, GO:0030425=GO_REF:0000039, GO:0030666=Reactome:REACT_18393, GO:0035235=GO_REF:0000024, GO:0032983=GO_REF:0000024, GO:0045211=GO_REF:0000039, GO:0030288=GO_REF:0000002, GO:0004971=PMID:21172611, GO:0032281=GO_REF:0000024, GO:0004970=GO_REF:0000024, GO:0006810=PMID:8589990, GO:0015277=GO_REF:0000024, GO:0016021=GO_REF:0000038} P48058 Glutamate receptor 4 protein 20130413 {GO:0005215=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0005234=IEA, GO:0007268=TAS, GO:0007215=TAS, GO:0030425=IEA, GO:0030666=TAS, GO:0035235=ISS, GO:0032983=ISS, GO:0045211=IEA, GO:0030288=IEA, GO:0004971=IDA, GO:0032281=ISS, GO:0004970=ISS, GO:0006810=TAS, GO:0015277=ISS, GO:0016021=IEA} glutamate receptor signaling pathway, ionotropic glutamate receptor signaling pathway, synaptic transmission, transport alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex, cell junction, dendrite, endocytic vesicle membrane, integral to membrane, kainate selective glutamate receptor complex, outer membrane-bounded periplasmic space, plasma membrane, postsynaptic membrane alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity, extracellular-glutamate-gated ion channel activity, ionotropic glutamate receptor activity, kainate selective glutamate receptor activity, transporter activity Human UniProtKB:P19493 GRID1 UniProtKB UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0045211=GO_REF:0000039, GO:0030288=GO_REF:0000002, GO:0005234=GO_REF:0000002, GO:0004970=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q9ULK0 Glutamate receptor ionotropic, delta-1 protein 20130413 {GO:0030054=IEA, GO:0005886=IEA, GO:0045211=IEA, GO:0030288=IEA, GO:0005234=IEA, GO:0004970=IEA, GO:0016021=IEA} cell junction, integral to membrane, outer membrane-bounded periplasmic space, plasma membrane, postsynaptic membrane extracellular-glutamate-gated ion channel activity, ionotropic glutamate receptor activity Human UniProtKB-SubCell:SL-0219 GRID2 BHF-UCL UniProtKB {GO:0030054=GO_REF:0000037, GO:0008328=GO_REF:0000024, GO:0005886=GO_REF:0000024, GO:0060134=GO_REF:0000024, GO:0005234=GO_REF:0000002, GO:0035249=GO_REF:0000024, GO:0060079=GO_REF:0000024, GO:0045202=GO_REF:0000024, GO:0007215=PMID:9465309, GO:0030165=GO_REF:0000024, GO:0043523=GO_REF:0000024, GO:0043197=GO_REF:0000024, GO:0005887=PMID:9465309, GO:0045211=GO_REF:0000039, GO:0030288=GO_REF:0000002, GO:0008066=PMID:9465309, GO:0097110=GO_REF:0000024, GO:0004970=GO_REF:0000002, GO:0006810=PMID:9465309, GO:0016021=GO_REF:0000038, GO:0034613=GO_REF:0000024} O43424 Glutamate receptor ionotropic, delta-2 protein 20120314 {GO:0030054=IEA, GO:0008328=ISS, GO:0005886=ISS, GO:0060134=ISS, GO:0005234=IEA, GO:0035249=ISS, GO:0060079=ISS, GO:0045202=ISS, GO:0007215=TAS, GO:0030165=ISS, GO:0043523=ISS, GO:0043197=ISS, GO:0005887=TAS, GO:0045211=IEA, GO:0030288=IEA, GO:0008066=TAS, GO:0097110=ISS, GO:0004970=IEA, GO:0006810=TAS, GO:0016021=IEA, GO:0034613=ISS} cellular protein localization, glutamate receptor signaling pathway, prepulse inhibition, regulation of excitatory postsynaptic membrane potential, regulation of neuron apoptotic process, synaptic transmission, glutamatergic, transport cell junction, dendritic spine, integral to membrane, integral to plasma membrane, ionotropic glutamate receptor complex, outer membrane-bounded periplasmic space, plasma membrane, postsynaptic membrane, synapse PDZ domain binding, extracellular-glutamate-gated ion channel activity, glutamate receptor activity, ionotropic glutamate receptor activity, scaffold protein binding Human UniProtKB:Q61625 GRID2IP InterPro UniProtKB {GO:0030054=GO_REF:0000037, GO:0030036=GO_REF:0000002, GO:0005886=GO_REF:0000037, GO:0045211=GO_REF:0000039, GO:0003779=GO_REF:0000002, GO:0060292=GO_REF:0000019} C9JNS8 Delphilin protein 20130413 {GO:0030054=IEA, GO:0030036=IEA, GO:0005886=IEA, GO:0045211=IEA, GO:0003779=IEA, GO:0060292=IEA} actin cytoskeleton organization, long term synaptic depression cell junction, plasma membrane, postsynaptic membrane actin binding Human InterPro:IPR003104 GRIK1 Reactome UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_21414, GO:0005234=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0014054=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0045211=GO_REF:0000039, GO:0004970=GO_REF:0000002, GO:0015277=PMID:9335499, GO:0006810=PMID:8260617, GO:0030534=GO_REF:0000019, GO:0051966=PMID:9335499, GO:0051967=GO_REF:0000019, GO:0035249=GO_REF:0000019, GO:0060079=GO_REF:0000019, GO:0007215=PMID:8260617, GO:0007417=PMID:10580501, GO:0032230=GO_REF:0000019, GO:0007399=PMID:8260617, GO:0042734=GO_REF:0000019, GO:0032983=GO_REF:0000019, GO:0060080=GO_REF:0000019, GO:0005887=PMID:8260617, GO:0016021=GO_REF:0000038, GO:0048266=GO_REF:0000019} P39086 Glutamate receptor ionotropic, kainate 1 protein 20130213 {GO:0030054=IEA, GO:0005886=TAS, GO:0005234=IEA, GO:0007268=TAS, GO:0014054=IEA, GO:0030425=IEA, GO:0045211=IEA, GO:0004970=IEA, GO:0015277=IDA, GO:0006810=TAS, GO:0030534=IEA, GO:0051966=TAS, GO:0051967=IEA, GO:0035249=IEA, GO:0060079=IEA, GO:0007215=TAS, GO:0007417=TAS, GO:0032230=IEA, GO:0007399=TAS, GO:0042734=IEA, GO:0032983=IEA, GO:0060080=IEA, GO:0005887=TAS, GO:0016021=IEA, GO:0048266=IEA} adult behavior, behavioral response to pain, central nervous system development, glutamate receptor signaling pathway, negative regulation of synaptic transmission, glutamatergic, nervous system development, positive regulation of gamma-aminobutyric acid secretion, positive regulation of synaptic transmission, GABAergic, regulation of excitatory postsynaptic membrane potential, regulation of inhibitory postsynaptic membrane potential, regulation of synaptic transmission, glutamatergic, synaptic transmission, synaptic transmission, glutamatergic, transport cell junction, dendrite, integral to membrane, integral to plasma membrane, kainate selective glutamate receptor complex, plasma membrane, postsynaptic membrane, presynaptic membrane extracellular-glutamate-gated ion channel activity, ionotropic glutamate receptor activity, kainate selective glutamate receptor activity Human GRIK2 Reactome UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_21414, GO:0005234=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0006886=GO_REF:0000019, GO:0019228=GO_REF:0000019, GO:0005622=GO_REF:0000019, GO:0043524=GO_REF:0000019, GO:0045211=GO_REF:0000039, GO:0004970=GO_REF:0000019, GO:0048169=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0015277=PMID:15537878, GO:0006810=PMID:7536611, GO:0001662=GO_REF:0000019, GO:0035249=GO_REF:0000019, GO:0006874=GO_REF:0000019, GO:0060079=GO_REF:0000019, GO:0050804=PMID:15537878, GO:0007215=PMID:7536611, GO:0042734=GO_REF:0000019, GO:0032983=GO_REF:0000019, GO:0060080=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0005887=PMID:7536611, GO:0050806=PMID:15537878, GO:0048172=PMID:15537878} Q13002 Glutamate receptor ionotropic, kainate 2 protein 20130213 {GO:0030054=IEA, GO:0005886=TAS, GO:0005234=IEA, GO:0007268=TAS, GO:0006886=IEA, GO:0019228=IEA, GO:0005622=IEA, GO:0043524=IEA, GO:0045211=IEA, GO:0004970=IEA, GO:0048169=IEA, GO:0043025=IEA, GO:0015277=IDA, GO:0006810=NAS, GO:0001662=IEA, GO:0035249=IEA, GO:0006874=IEA, GO:0060079=IEA, GO:0050804=IDA, GO:0007215=TAS, GO:0042734=IEA, GO:0032983=IEA, GO:0060080=IEA, GO:0016020=IEA, GO:0005887=TAS, GO:0050806=IMP, GO:0048172=IMP} behavioral fear response, cellular calcium ion homeostasis, glutamate receptor signaling pathway, intracellular protein transport, negative regulation of neuron apoptotic process, positive regulation of synaptic transmission, regulation of action potential in neuron, regulation of excitatory postsynaptic membrane potential, regulation of inhibitory postsynaptic membrane potential, regulation of long-term neuronal synaptic plasticity, regulation of short-term neuronal synaptic plasticity, regulation of synaptic transmission, synaptic transmission, synaptic transmission, glutamatergic, transport cell junction, integral to plasma membrane, intracellular, kainate selective glutamate receptor complex, membrane, neuronal cell body, plasma membrane, postsynaptic membrane, presynaptic membrane extracellular-glutamate-gated ion channel activity, ionotropic glutamate receptor activity, kainate selective glutamate receptor activity Human GRIK3 GOC UniProtKB {GO:0030424=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_21414, GO:0001640=PMID:9144652, GO:0005234=GO_REF:0000002, GO:0051967=GO_REF:0000024, GO:0007216=PMID:9144652, GO:0007268=Reactome:REACT_13685, GO:0007196=PMID:9144652, GO:0032839=GO_REF:0000024, GO:0007215=PMID:7719709, GO:0030425=GO_REF:0000024, GO:0035235=PMID:11124978, GO:0005887=PMID:7719709, GO:0043195=GO_REF:0000024, GO:0045211=GO_REF:0000039, GO:0004970=PMID:11124978, GO:0008066=PMID:8128318, GO:0042391=PMID:11124978, GO:0015277=PMID:7719709, GO:0043204=GO_REF:0000024, GO:0016021=GO_REF:0000038} Q13003 Glutamate receptor ionotropic, kainate 3 protein 20130413 {GO:0030424=ISS, GO:0030054=IEA, GO:0005886=TAS, GO:0001640=IDA, GO:0005234=IEA, GO:0051967=ISS, GO:0007216=IDA, GO:0007268=TAS, GO:0007196=IDA, GO:0032839=ISS, GO:0007215=IDA, GO:0030425=ISS, GO:0035235=IDA, GO:0005887=IDA, GO:0043195=ISS, GO:0045211=IEA, GO:0004970=IDA, GO:0008066=TAS, GO:0042391=IDA, GO:0015277=IDA, GO:0043204=ISS, GO:0016021=IEA} G-protein coupled glutamate receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway, glutamate receptor signaling pathway, ionotropic glutamate receptor signaling pathway, negative regulation of synaptic transmission, glutamatergic, regulation of membrane potential, synaptic transmission axon, cell junction, dendrite, dendrite cytoplasm, integral to membrane, integral to plasma membrane, perikaryon, plasma membrane, postsynaptic membrane, terminal bouton adenylate cyclase inhibiting G-protein coupled glutamate receptor activity, extracellular-glutamate-gated ion channel activity, glutamate receptor activity, ionotropic glutamate receptor activity, kainate selective glutamate receptor activity Human GRIK4 Reactome UniProtKB {GO:0042734=GO_REF:0000019, GO:0032983=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_21414, GO:0005887=PMID:8263508, GO:0045211=GO_REF:0000039, GO:0005234=GO_REF:0000002, GO:0015277=PMID:8263508, GO:0006810=PMID:8263508, GO:0007268=Reactome:REACT_13685, GO:0007215=PMID:8263508} Q16099 Glutamate receptor ionotropic, kainate 4 protein 20100205 {GO:0042734=IEA, GO:0032983=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0005887=TAS, GO:0045211=IEA, GO:0005234=IEA, GO:0015277=TAS, GO:0006810=TAS, GO:0007268=TAS, GO:0007215=TAS} glutamate receptor signaling pathway, synaptic transmission, transport cell junction, integral to plasma membrane, kainate selective glutamate receptor complex, plasma membrane, postsynaptic membrane, presynaptic membrane extracellular-glutamate-gated ion channel activity, kainate selective glutamate receptor activity Human GRIK5 Reactome UniProtKB {GO:0017124=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_21414, GO:0005234=GO_REF:0000002, GO:0060079=GO_REF:0000019, GO:0035249=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0014069=GO_REF:0000019, GO:0030165=GO_REF:0000019, GO:0042802=GO_REF:0000019, GO:0042734=GO_REF:0000019, GO:0043525=GO_REF:0000019, GO:0032983=GO_REF:0000019, GO:0043195=GO_REF:0000019, GO:0045211=GO_REF:0000039, GO:0031630=GO_REF:0000019, GO:0015277=PMID:1321949, GO:0051649=GO_REF:0000019, GO:0043204=GO_REF:0000019, GO:0043113=GO_REF:0000019, GO:0016021=GO_REF:0000029, GO:0006621=GO_REF:0000019, GO:0071333=GO_REF:0000019} Q16478 Glutamate receptor ionotropic, kainate 5 protein 20091216 {GO:0017124=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0005234=IEA, GO:0060079=IEA, GO:0035249=IEA, GO:0007268=TAS, GO:0014069=IEA, GO:0030165=IEA, GO:0042802=IEA, GO:0042734=IEA, GO:0043525=IEA, GO:0032983=IEA, GO:0043195=IEA, GO:0045211=IEA, GO:0031630=IEA, GO:0015277=IDA, GO:0051649=IEA, GO:0043204=IEA, GO:0043113=IEA, GO:0016021=NAS, GO:0006621=IEA, GO:0071333=IEA} cellular response to glucose stimulus, establishment of localization in cell, positive regulation of neuron apoptotic process, protein retention in ER lumen, receptor clustering, regulation of excitatory postsynaptic membrane potential, regulation of synaptic vesicle fusion to presynaptic membrane, synaptic transmission, synaptic transmission, glutamatergic cell junction, integral to membrane, kainate selective glutamate receptor complex, perikaryon, plasma membrane, postsynaptic density, postsynaptic membrane, presynaptic membrane, terminal bouton PDZ domain binding, SH3 domain binding, extracellular-glutamate-gated ion channel activity, identical protein binding, kainate selective glutamate receptor activity Human GRIN1 UniProtKB UniProtKB {GO:0005515=PMID:17997397, GO:0005516=GO_REF:0000024, GO:0043005=GO_REF:0000024, GO:0030054=GO_REF:0000038, GO:0005886=GO_REF:0000038, GO:0045471=PMID:18445116, GO:0017146=PMID:17047094, GO:0005234=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0045202=GO_REF:0000024, GO:0030425=PMID:10749211, GO:0055074=GO_REF:0000024, GO:0043197=GO_REF:0000024, GO:0004972=PMID:7679115, GO:0043195=GO_REF:0000024, GO:0045944=GO_REF:0000024, GO:0045211=GO_REF:0000038, GO:0004970=GO_REF:0000002, GO:0042391=PMID:7679115, GO:0042165=GO_REF:0000024, GO:0006812=PMID:7685113, GO:0005262=PMID:7685113, GO:2000463=GO_REF:0000024, GO:0009986=GO_REF:0000024, GO:0005509=GO_REF:0000024, GO:0060079=GO_REF:0000024, GO:0014069=GO_REF:0000024, GO:0043083=GO_REF:0000024, GO:0060076=GO_REF:0000024, GO:0008021=GO_REF:0000024, GO:0035235=GO_REF:0000024, GO:0005887=PMID:7685113, GO:0030288=GO_REF:0000002, GO:0008542=GO_REF:0000024, GO:0070588=PMID:7685113, GO:0016594=PMID:17047094, GO:0016595=PMID:7685113, GO:0016021=GO_REF:0000038} Q5VSF9 Glutamate receptor ionotropic, NMDA 1 protein 20130413 {GO:0005515=IPI, GO:0005516=ISS, GO:0043005=ISS, GO:0030054=IEA, GO:0005886=IEA, GO:0045471=IDA, GO:0017146=IDA, GO:0005234=IEA, GO:0007268=TAS, GO:0045202=ISS, GO:0030425=IDA, GO:0055074=ISS, GO:0043197=ISS, GO:0004972=IDA, GO:0043195=ISS, GO:0045944=ISS, GO:0045211=IEA, GO:0004970=IEA, GO:0042391=IDA, GO:0042165=ISS, GO:0006812=IDA, GO:0005262=IDA, GO:2000463=ISS, GO:0009986=ISS, GO:0005509=ISS, GO:0060079=ISS, GO:0014069=ISS, GO:0043083=ISS, GO:0060076=ISS, GO:0008021=ISS, GO:0035235=ISS, GO:0005887=IDA, GO:0030288=IEA, GO:0008542=ISS, GO:0070588=IDA, GO:0016594=IMP, GO:0016595=IDA, GO:0016021=IEA} calcium ion homeostasis, calcium ion transmembrane transport, cation transport, ionotropic glutamate receptor signaling pathway, positive regulation of excitatory postsynaptic membrane potential, positive regulation of transcription from RNA polymerase II promoter, regulation of excitatory postsynaptic membrane potential, regulation of membrane potential, response to ethanol, synaptic transmission, visual learning N-methyl-D-aspartate selective glutamate receptor complex, cell junction, cell surface, dendrite, dendritic spine, excitatory synapse, integral to membrane, integral to plasma membrane, neuron projection, outer membrane-bounded periplasmic space, plasma membrane, postsynaptic density, postsynaptic membrane, synapse, synaptic cleft, synaptic vesicle, terminal bouton N-methyl-D-aspartate selective glutamate receptor activity, calcium channel activity, calcium ion binding, calmodulin binding, extracellular-glutamate-gated ion channel activity, glutamate binding, glycine binding, ionotropic glutamate receptor activity, neurotransmitter binding, protein binding Human UniProtKB-KW:KW-0628 GRIN2A BHF-UCL UniProtKB {GO:0005515=PMID:17997397, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_20670, GO:0045471=PMID:18445116, GO:0017146=PMID:10480938, GO:0005234=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0001964=GO_REF:0000019, GO:0008104=GO_REF:0000019, GO:0042417=GO_REF:0000019, GO:0048167=GO_REF:0000019, GO:0004972=GO_REF:0000019, GO:0045211=GO_REF:0000039, GO:0004970=GO_REF:0000002, GO:0007611=PMID:7816096, GO:0006810=PMID:8768735, GO:0007613=GO_REF:0000019, GO:0022008=GO_REF:0000019, GO:0005262=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0009986=GO_REF:0000024, GO:0033058=GO_REF:0000019, GO:0042177=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0060079=GO_REF:0000019, GO:0009611=GO_REF:0000019, GO:0014069=GO_REF:0000019, GO:0030431=GO_REF:0000019, GO:0007215=PMID:8768735, GO:0019233=GO_REF:0000019, GO:0042428=GO_REF:0000019, GO:0042734=GO_REF:0000019, GO:0001975=GO_REF:0000019, GO:0005887=PMID:8768735, GO:0030288=GO_REF:0000002, GO:0008542=GO_REF:0000019, GO:0008270=GO_REF:0000024, GO:0016021=GO_REF:0000038, GO:0051930=GO_REF:0000019} Q12879 Glutamate receptor ionotropic, NMDA 2A protein 20120316 {GO:0005515=IPI, GO:0030054=IEA, GO:0005886=TAS, GO:0045471=IDA, GO:0017146=IDA, GO:0005234=IEA, GO:0007268=TAS, GO:0001964=IEA, GO:0008104=IEA, GO:0042417=IEA, GO:0048167=IEA, GO:0004972=IEA, GO:0045211=IEA, GO:0004970=IEA, GO:0007611=TAS, GO:0006810=TAS, GO:0007613=IEA, GO:0022008=IEA, GO:0005262=IEA, GO:0043065=IEA, GO:0009986=ISS, GO:0033058=IEA, GO:0042177=IEA, GO:0042493=IEA, GO:0060079=IEA, GO:0009611=IEA, GO:0014069=IEA, GO:0030431=IEA, GO:0007215=TAS, GO:0019233=IEA, GO:0042428=IEA, GO:0042734=IEA, GO:0001975=IEA, GO:0005887=TAS, GO:0030288=IEA, GO:0008542=IEA, GO:0008270=ISS, GO:0016021=IEA, GO:0051930=IEA} directional locomotion, dopamine metabolic process, glutamate receptor signaling pathway, learning or memory, memory, negative regulation of protein catabolic process, neurogenesis, positive regulation of apoptotic process, protein localization, regulation of excitatory postsynaptic membrane potential, regulation of sensory perception of pain, regulation of synaptic plasticity, response to amphetamine, response to drug, response to ethanol, response to wounding, sensory perception of pain, serotonin metabolic process, sleep, startle response, synaptic transmission, transport, visual learning N-methyl-D-aspartate selective glutamate receptor complex, cell junction, cell surface, integral to membrane, integral to plasma membrane, outer membrane-bounded periplasmic space, plasma membrane, postsynaptic density, postsynaptic membrane, presynaptic membrane N-methyl-D-aspartate selective glutamate receptor activity, calcium channel activity, extracellular-glutamate-gated ion channel activity, ionotropic glutamate receptor activity, protein binding, zinc ion binding Human UniProtKB:P35436 GRIN2B BHF-UCL UniProtKB {GO:0005515=PMID:17997397, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_20670, GO:0005234=GO_REF:0000002, GO:0017146=PMID:17047094, GO:0045471=PMID:18445116, GO:0007268=Reactome:REACT_13685, GO:0001964=GO_REF:0000019, GO:0001967=GO_REF:0000019, GO:0004972=GO_REF:0000019, GO:0048167=GO_REF:0000019, GO:0045211=GO_REF:0000039, GO:0007611=PMID:10485705, GO:0006810=PMID:8768735, GO:0007613=GO_REF:0000019, GO:0001662=GO_REF:0000019, GO:0050966=GO_REF:0000019, GO:0007612=GO_REF:0000019, GO:0005262=GO_REF:0000019, GO:0009986=GO_REF:0000024, GO:0060079=GO_REF:0000019, GO:0014069=GO_REF:0000019, GO:0007215=PMID:8768735, GO:0001701=GO_REF:0000019, GO:0008021=GO_REF:0000019, GO:0007423=GO_REF:0000019, GO:0005887=PMID:8768735, GO:0030288=GO_REF:0000002, GO:0016594=PMID:17047094, GO:0008270=GO_REF:0000024, GO:0048266=GO_REF:0000019} Q13224 Glutamate receptor ionotropic, NMDA 2B protein 20120316 {GO:0005515=IPI, GO:0030054=IEA, GO:0005886=TAS, GO:0005234=IEA, GO:0017146=IDA, GO:0045471=IDA, GO:0007268=TAS, GO:0001964=IEA, GO:0001967=IEA, GO:0004972=IEA, GO:0048167=IEA, GO:0045211=IEA, GO:0007611=TAS, GO:0006810=TAS, GO:0007613=IEA, GO:0001662=IEA, GO:0050966=IEA, GO:0007612=IEA, GO:0005262=IEA, GO:0009986=ISS, GO:0060079=IEA, GO:0014069=IEA, GO:0007215=TAS, GO:0001701=IEA, GO:0008021=IEA, GO:0007423=IEA, GO:0005887=TAS, GO:0030288=IEA, GO:0016594=IDA, GO:0008270=ISS, GO:0048266=IEA} behavioral fear response, behavioral response to pain, detection of mechanical stimulus involved in sensory perception of pain, glutamate receptor signaling pathway, in utero embryonic development, learning, learning or memory, memory, regulation of excitatory postsynaptic membrane potential, regulation of synaptic plasticity, response to ethanol, sensory organ development, startle response, suckling behavior, synaptic transmission, transport N-methyl-D-aspartate selective glutamate receptor complex, cell junction, cell surface, integral to plasma membrane, outer membrane-bounded periplasmic space, plasma membrane, postsynaptic density, postsynaptic membrane, synaptic vesicle N-methyl-D-aspartate selective glutamate receptor activity, calcium channel activity, extracellular-glutamate-gated ion channel activity, glycine binding, protein binding, zinc ion binding Human UniProtKB:Q01097 GRIN2C HPA UniProtKB {GO:0030054=GO_REF:0000037, GO:0005261=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0042177=GO_REF:0000019, GO:0033058=GO_REF:0000019, GO:0005234=GO_REF:0000002, GO:0017146=GO_REF:0000019, GO:0060079=GO_REF:0000019, GO:0009611=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0014069=GO_REF:0000019, GO:0007215=PMID:9798920, GO:0030165=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0047485=GO_REF:0000019, GO:0008104=GO_REF:0000019, GO:0005887=PMID:9798920, GO:0004972=GO_REF:0000019, GO:0030288=GO_REF:0000002, GO:0045211=GO_REF:0000039, GO:0004970=GO_REF:0000002, GO:0006810=PMID:9798920, GO:0050885=GO_REF:0000019, GO:0016021=GO_REF:0000038} Q14957 Glutamate receptor ionotropic, NMDA 2C protein 20110516 {GO:0030054=IEA, GO:0005261=IEA, GO:0005886=IDA, GO:0042177=IEA, GO:0033058=IEA, GO:0005234=IEA, GO:0017146=IEA, GO:0060079=IEA, GO:0009611=IEA, GO:0007268=TAS, GO:0014069=IEA, GO:0007215=TAS, GO:0030165=IEA, GO:0005737=IDA, GO:0047485=IEA, GO:0008104=IEA, GO:0005887=TAS, GO:0004972=IEA, GO:0030288=IEA, GO:0045211=IEA, GO:0004970=IEA, GO:0006810=TAS, GO:0050885=IEA, GO:0016021=IEA} directional locomotion, glutamate receptor signaling pathway, negative regulation of protein catabolic process, neuromuscular process controlling balance, protein localization, regulation of excitatory postsynaptic membrane potential, response to wounding, synaptic transmission, transport N-methyl-D-aspartate selective glutamate receptor complex, cell junction, cytoplasm, integral to membrane, integral to plasma membrane, outer membrane-bounded periplasmic space, plasma membrane, postsynaptic density, postsynaptic membrane N-methyl-D-aspartate selective glutamate receptor activity, PDZ domain binding, cation channel activity, extracellular-glutamate-gated ion channel activity, ionotropic glutamate receptor activity, protein N-terminus binding Human GRIN2D Reactome UniProtKB {GO:0001964=GO_REF:0000019, GO:0007165=PMID:9480759, GO:0008344=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_20670, GO:0004972=GO_REF:0000019, GO:0045211=GO_REF:0000039, GO:0030288=GO_REF:0000002, GO:0005234=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0016021=GO_REF:0000037, GO:0051930=GO_REF:0000019} O15399 Glutamate receptor ionotropic, NMDA 2D protein 20130301 {GO:0001964=IEA, GO:0007165=NAS, GO:0008344=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0004972=IEA, GO:0045211=IEA, GO:0030288=IEA, GO:0005234=IEA, GO:0007268=TAS, GO:0016021=IEA, GO:0051930=IEA} adult locomotory behavior, regulation of sensory perception of pain, signal transduction, startle response, synaptic transmission cell junction, integral to membrane, outer membrane-bounded periplasmic space, plasma membrane, postsynaptic membrane N-methyl-D-aspartate selective glutamate receptor activity, extracellular-glutamate-gated ion channel activity Human GRIN3A UniProtKB UniProtKB {GO:0005515=PMID:17658481, GO:0043005=PMID:17658481, GO:0005262=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0017146=PMID:17997397, GO:0045471=PMID:18445116, GO:0005234=GO_REF:0000002, GO:0060134=GO_REF:0000019, GO:0014069=GO_REF:0000039, GO:0045202=PMID:17658481, GO:0016358=GO_REF:0000019, GO:0042802=PMID:17997397, GO:0016020=PMID:17997397, GO:0004972=GO_REF:0000024, GO:0030288=GO_REF:0000002, GO:0045211=GO_REF:0000039, GO:0016594=PMID:17320117, GO:0043025=PMID:17658481, GO:0042165=GO_REF:0000019, GO:0006816=GO_REF:0000024, GO:0016021=PMID:11880201, GO:0048511=GO_REF:0000019, GO:0051721=GO_REF:0000024} Q8TCU5 Glutamate receptor ionotropic, NMDA 3A protein 20080704 {GO:0005515=IPI, GO:0043005=IDA, GO:0005262=IEA, GO:0030054=IEA, GO:0017146=IDA, GO:0045471=IDA, GO:0005234=IEA, GO:0060134=IEA, GO:0014069=IEA, GO:0045202=IDA, GO:0016358=IEA, GO:0042802=IPI, GO:0016020=IDA, GO:0004972=ISS, GO:0030288=IEA, GO:0045211=IEA, GO:0016594=IDA, GO:0043025=IDA, GO:0042165=IEA, GO:0006816=ISS, GO:0016021=NAS, GO:0048511=IEA, GO:0051721=ISS} calcium ion transport, dendrite development, prepulse inhibition, response to ethanol, rhythmic process N-methyl-D-aspartate selective glutamate receptor complex, cell junction, integral to membrane, membrane, neuron projection, neuronal cell body, outer membrane-bounded periplasmic space, postsynaptic density, postsynaptic membrane, synapse N-methyl-D-aspartate selective glutamate receptor activity, calcium channel activity, extracellular-glutamate-gated ion channel activity, glycine binding, identical protein binding, neurotransmitter binding, protein binding, protein phosphatase 2A binding Human UniProtKB:Q66K74 GRIN3B GOC UniProtKB {GO:0005262=PMID:11735224, GO:0030054=GO_REF:0000037, GO:0005261=GO_REF:0000024, GO:0005234=GO_REF:0000002, GO:0017146=PMID:11735224, GO:0030594=GO_REF:0000024, GO:0051205=PMID:11735224, GO:0007268=GO_REF:0000024, GO:0035235=GO_REF:0000024, GO:0030288=GO_REF:0000002, GO:0045211=GO_REF:0000039, GO:0004970=GO_REF:0000002, GO:0016594=GO_REF:0000024, GO:0043025=PMID:11735224, GO:0051924=PMID:11735224, GO:0042165=GO_REF:0000024} O60391 Glutamate receptor ionotropic, NMDA 3B protein 20130413 {GO:0005262=ISS, GO:0030054=IEA, GO:0005261=ISS, GO:0005234=IEA, GO:0017146=ISS, GO:0030594=ISS, GO:0051205=ISS, GO:0007268=ISS, GO:0035235=ISS, GO:0030288=IEA, GO:0045211=IEA, GO:0004970=IEA, GO:0016594=ISS, GO:0043025=ISS, GO:0051924=ISS, GO:0042165=ISS} ionotropic glutamate receptor signaling pathway, protein insertion into membrane, regulation of calcium ion transport, synaptic transmission N-methyl-D-aspartate selective glutamate receptor complex, cell junction, neuronal cell body, outer membrane-bounded periplasmic space, postsynaptic membrane calcium channel activity, cation channel activity, extracellular-glutamate-gated ion channel activity, glycine binding, ionotropic glutamate receptor activity, neurotransmitter binding, neurotransmitter receptor activity Human UniProtKB:Q8VHN2 GRIP1 BHF-UCL UniProtKB {GO:0043005=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0008013=PMID:16344550, GO:0005886=GO_REF:0000024, GO:0005783=GO_REF:0000039, GO:0003713=PMID:15572661, GO:0007268=Reactome:REACT_13685, GO:0030159=PMID:10197531, GO:0050681=PMID:15572661, GO:0008022=PMID:16344550, GO:0005829=Reactome:REACT_18330, GO:0035556=PMID:10197531, GO:0008104=GO_REF:0000019, GO:0045211=GO_REF:0000039, GO:0016023=GO_REF:0000039, GO:0045121=GO_REF:0000019, GO:0045893=PMID:15572661, GO:0030521=PMID:15572661} Q9Y3R0 Glutamate receptor-interacting protein 1 protein 20120815 {GO:0043005=ISS, GO:0030054=IEA, GO:0008013=TAS, GO:0005886=ISS, GO:0005783=IEA, GO:0003713=NAS, GO:0007268=TAS, GO:0030159=NAS, GO:0050681=NAS, GO:0008022=IPI, GO:0005829=TAS, GO:0035556=NAS, GO:0008104=IEA, GO:0045211=IEA, GO:0016023=IEA, GO:0045121=IEA, GO:0045893=NAS, GO:0030521=NAS} androgen receptor signaling pathway, intracellular signal transduction, positive regulation of transcription, DNA-dependent, protein localization, synaptic transmission cell junction, cytoplasmic membrane-bounded vesicle, cytosol, endoplasmic reticulum, membrane raft, neuron projection, plasma membrane, postsynaptic membrane androgen receptor binding, beta-catenin binding, protein C-terminus binding, receptor signaling complex scaffold activity, transcription coactivator activity Human UniProtKB:Q925T6 GRIP2 Reactome UniProtKB {GO:0005886=Reactome:REACT_18330, GO:0007268=Reactome:REACT_13685, GO:0005829=Reactome:REACT_18330} Q9C0E4 Glutamate receptor-interacting protein 2 protein 20130301 {GO:0005886=TAS, GO:0007268=TAS, GO:0005829=TAS} synaptic transmission cytosol, plasma membrane Human GRIPAP1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0005769=GO_REF:0000039} Q4V328 GRIP1-associated protein 1 protein 20061106 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND, GO:0005769=IEA} biological_process cellular_component, early endosome molecular_function Human GRK1 PINC UniProtKB {GO:0006915=GO_REF:0000019, GO:0038032=GO_REF:0000002, GO:0022400=PMID:15946941, GO:0050254=PMID:15946941, GO:0005524=GO_REF:0000037, GO:0008277=PMID:1656454, GO:0004672=PMID:9147475, GO:0004703=GO_REF:0000002, GO:0046777=PMID:15946941, GO:0016020=GO_REF:0000039, GO:0004674=GO_REF:0000038, GO:0009416=GO_REF:0000019, GO:0060060=GO_REF:0000019, GO:0008594=GO_REF:0000019, GO:0007601=GO_REF:0000037, GO:0016056=PMID:9147475, GO:0042327=GO_REF:0000019} Q15835 Rhodopsin kinase protein 20030904 {GO:0006915=IEA, GO:0038032=IEA, GO:0022400=IDA, GO:0050254=IDA, GO:0005524=IEA, GO:0008277=TAS, GO:0004672=TAS, GO:0004703=IEA, GO:0046777=IMP, GO:0016020=IEA, GO:0004674=IEA, GO:0009416=IEA, GO:0060060=IEA, GO:0008594=IEA, GO:0007601=IEA, GO:0016056=TAS, GO:0042327=IEA} apoptotic process, photoreceptor cell morphogenesis, positive regulation of phosphorylation, post-embryonic retina morphogenesis in camera-type eye, protein autophosphorylation, regulation of G-protein coupled receptor protein signaling pathway, regulation of rhodopsin mediated signaling pathway, response to light stimulus, rhodopsin mediated signaling pathway, termination of G-protein coupled receptor signaling pathway, visual perception membrane ATP binding, G-protein coupled receptor kinase activity, protein kinase activity, protein serine/threonine kinase activity, rhodopsin kinase activity Human GRK4 PINC UniProtKB {GO:0031623=PMID:20074556, GO:0007165=GO_REF:0000002, GO:0008277=PMID:1338872, GO:0004703=GO_REF:0000003, GO:0043025=GO_REF:0000019, GO:0038032=GO_REF:0000002, GO:0050254=GO_REF:0000019, GO:0005938=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0030425=GO_REF:0000019, GO:0002031=GO_REF:0000019, GO:0005829=GO_REF:0000019} P32298 G protein-coupled receptor kinase 4 protein 20030904 {GO:0031623=IDA, GO:0007165=IEA, GO:0008277=TAS, GO:0004703=IEA, GO:0043025=IEA, GO:0038032=IEA, GO:0050254=IEA, GO:0005938=IEA, GO:0005524=IEA, GO:0030425=IEA, GO:0002031=IEA, GO:0005829=IEA} G-protein coupled receptor internalization, receptor internalization, regulation of G-protein coupled receptor protein signaling pathway, signal transduction, termination of G-protein coupled receptor signaling pathway cell cortex, cytosol, dendrite, neuronal cell body ATP binding, G-protein coupled receptor kinase activity, rhodopsin kinase activity Human GRK5 BHF-UCL UniProtKB {GO:0005515=PMID:17986524, GO:0043066=PMID:20124405, GO:0005886=PMID:17986524, GO:0007217=PMID:17986524, GO:0038032=GO_REF:0000002, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0008277=PMID:8288567, GO:0005543=PMID:9813065, GO:0004703=GO_REF:0000003, GO:0046777=PMID:14976207, GO:0004674=PMID:20124405, GO:0005080=PMID:9813065, GO:0007188=PMID:8626574, GO:0016055=GO_REF:0000037} P34947 G protein-coupled receptor kinase 5 protein 20080206 {GO:0005515=IPI, GO:0043066=IDA, GO:0005886=IDA, GO:0007217=IDA, GO:0038032=IEA, GO:0006915=IEA, GO:0005634=IEA, GO:0005524=IEA, GO:0007165=IEA, GO:0005737=IEA, GO:0008277=TAS, GO:0005543=TAS, GO:0004703=IEA, GO:0046777=IDA, GO:0004674=IDA, GO:0005080=TAS, GO:0007188=TAS, GO:0016055=IEA} Wnt receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, apoptotic process, negative regulation of apoptotic process, protein autophosphorylation, regulation of G-protein coupled receptor protein signaling pathway, signal transduction, tachykinin receptor signaling pathway, termination of G-protein coupled receptor signaling pathway cytoplasm, nucleus, plasma membrane ATP binding, G-protein coupled receptor kinase activity, phospholipid binding, protein binding, protein kinase C binding, protein serine/threonine kinase activity Human GRK6 PINC UniProtKB {GO:0007165=GO_REF:0000002, GO:0008277=PMID:8077221, GO:0004703=GO_REF:0000003, GO:0016020=GO_REF:0000039, GO:0038032=GO_REF:0000002, GO:0016055=GO_REF:0000037, GO:0005524=GO_REF:0000037} P43250 G protein-coupled receptor kinase 6 protein 20030904 {GO:0007165=IEA, GO:0008277=TAS, GO:0004703=IEA, GO:0016020=IEA, GO:0038032=IEA, GO:0016055=IEA, GO:0005524=IEA} Wnt receptor signaling pathway, regulation of G-protein coupled receptor protein signaling pathway, signal transduction, termination of G-protein coupled receptor signaling pathway membrane ATP binding, G-protein coupled receptor kinase activity Human GRK7 UniProtKB UniProtKB {GO:0007165=GO_REF:0000002, GO:0046777=PMID:15946941, GO:0004703=GO_REF:0000003, GO:0016020=GO_REF:0000039, GO:0038032=GO_REF:0000002, GO:0050254=PMID:15946941, GO:0007601=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q8WTQ7 G protein-coupled receptor kinase 7 protein 20110719 {GO:0007165=IEA, GO:0046777=IMP, GO:0004703=IEA, GO:0016020=IEA, GO:0038032=IEA, GO:0050254=IDA, GO:0007601=IEA, GO:0005524=IEA} protein autophosphorylation, signal transduction, termination of G-protein coupled receptor signaling pathway, visual perception membrane ATP binding, G-protein coupled receptor kinase activity, rhodopsin kinase activity Human GRM1 Reactome UniProtKB {GO:0008219=GO_REF:0000037, GO:0005886=Reactome:REACT_18380, GO:0004930=PMID:7476890, GO:0007268=PMID:9076744, GO:0014069=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0019233=GO_REF:0000019, GO:0000187=GO_REF:0000019, GO:0000186=GO_REF:0000019, GO:0071257=GO_REF:0000019, GO:0007186=PMID:7476890, GO:0005887=PMID:7476890, GO:0008066=PMID:7476890, GO:0007626=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0051930=GO_REF:0000019} Q13255 Metabotropic glutamate receptor 1 protein 20090512 {GO:0008219=IEA, GO:0005886=TAS, GO:0004930=TAS, GO:0007268=TAS, GO:0014069=IEA, GO:0005634=IEA, GO:0019233=IEA, GO:0000187=IEA, GO:0000186=IEA, GO:0071257=IEA, GO:0007186=TAS, GO:0005887=TAS, GO:0008066=TAS, GO:0007626=IEA, GO:0016021=IEA, GO:0051930=IEA} G-protein coupled receptor signaling pathway, activation of MAPK activity, activation of MAPKK activity, cell death, cellular response to electrical stimulus, locomotory behavior, regulation of sensory perception of pain, sensory perception of pain, synaptic transmission integral to membrane, integral to plasma membrane, nucleus, plasma membrane, postsynaptic density G-protein coupled receptor activity, glutamate receptor activity Human GRM2 Reactome UniProtKB {GO:0030424=GO_REF:0000019, GO:0005886=Reactome:REACT_18380, GO:0005246=GO_REF:0000019, GO:0004930=PMID:7620613, GO:0001641=GO_REF:0000019, GO:0007268=PMID:7620613, GO:0007194=PMID:7620613, GO:0014047=GO_REF:0000019, GO:0005622=GO_REF:0000019, GO:0042734=GO_REF:0000019, GO:0005887=PMID:7620613, GO:0008066=PMID:7620613, GO:0016021=GO_REF:0000002} Q14416 Metabotropic glutamate receptor 2 protein 20090512 {GO:0030424=IEA, GO:0005886=TAS, GO:0005246=IEA, GO:0004930=TAS, GO:0001641=IEA, GO:0007268=TAS, GO:0007194=TAS, GO:0014047=IEA, GO:0005622=IEA, GO:0042734=IEA, GO:0005887=TAS, GO:0008066=TAS, GO:0016021=IEA} glutamate secretion, negative regulation of adenylate cyclase activity, synaptic transmission axon, integral to membrane, integral to plasma membrane, intracellular, plasma membrane, presynaptic membrane G-protein coupled receptor activity, calcium channel regulator activity, glutamate receptor activity, group II metabotropic glutamate receptor activity Human GRM3 InterPro UniProtKB {GO:0030424=GO_REF:0000019, GO:0005886=Reactome:REACT_18380, GO:0004930=GO_REF:0000002, GO:0005246=GO_REF:0000019, GO:0001641=GO_REF:0000019, GO:0007268=PMID:8840013, GO:0014069=GO_REF:0000019, GO:0050804=GO_REF:0000019, GO:0007194=PMID:8840013, GO:0042734=GO_REF:0000019, GO:0005887=PMID:8840013, GO:0045211=GO_REF:0000019, GO:0008066=PMID:8840013, GO:0016021=GO_REF:0000002} Q2PNZ6 Metabotropic glutamate receptor 3 protein 20130413 {GO:0030424=IEA, GO:0005886=TAS, GO:0004930=IEA, GO:0005246=IEA, GO:0001641=IEA, GO:0007268=TAS, GO:0014069=IEA, GO:0050804=IEA, GO:0007194=TAS, GO:0042734=IEA, GO:0005887=TAS, GO:0045211=IEA, GO:0008066=TAS, GO:0016021=IEA} negative regulation of adenylate cyclase activity, regulation of synaptic transmission, synaptic transmission axon, integral to membrane, integral to plasma membrane, plasma membrane, postsynaptic density, postsynaptic membrane, presynaptic membrane G-protein coupled receptor activity, calcium channel regulator activity, glutamate receptor activity, group II metabotropic glutamate receptor activity Human InterPro:IPR000162|InterPro:IPR000337|InterPro:IPR001234|InterPro:IPR017979 GRM4 UniProtKB UniProtKB {GO:0005886=GO_REF:0000040, GO:0004930=GO_REF:0000038, GO:0007268=PMID:8738157, GO:0007196=PMID:15102938, GO:0031410=PMID:15102938, GO:0007269=PMID:15102938, GO:0005622=PMID:15102938, GO:0043523=PMID:15102938, GO:0000187=PMID:15102938, GO:0043198=GO_REF:0000019, GO:0005887=PMID:15102938, GO:0043195=GO_REF:0000019, GO:0008066=PMID:9473604, GO:0016021=GO_REF:0000038, GO:0007612=GO_REF:0000019, GO:0043410=PMID:15102938, GO:0048787=GO_REF:0000019} Q6ZMQ2 cDNA FLJ16766 fis, clone BRAWH3013197, highly similar to Metabotropic glutamate receptor 4 protein 20130413 {GO:0005886=IEA, GO:0004930=IEA, GO:0007268=TAS, GO:0007196=IMP, GO:0031410=IDA, GO:0007269=TAS, GO:0005622=IDA, GO:0043523=TAS, GO:0000187=IDA, GO:0043198=IEA, GO:0005887=IDA, GO:0043195=IEA, GO:0008066=TAS, GO:0016021=IEA, GO:0007612=IEA, GO:0043410=IEP, GO:0048787=IEA} activation of MAPK activity, adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway, learning, neurotransmitter secretion, positive regulation of MAPK cascade, regulation of neuron apoptotic process, synaptic transmission cytoplasmic vesicle, dendritic shaft, integral to membrane, integral to plasma membrane, intracellular, plasma membrane, presynaptic active zone membrane, terminal bouton G-protein coupled receptor activity, glutamate receptor activity Human UniProtKB-SubCell:SL-0039 GRM5 UniProtKB UniProtKB {GO:0006355=GO_REF:0000019, GO:0005886=GO_REF:0000040, GO:0004930=GO_REF:0000038, GO:0031687=GO_REF:0000019, GO:0007268=GO_REF:0000019, GO:0014069=GO_REF:0000019, GO:0007205=GO_REF:0000019, GO:0007206=PMID:7908515, GO:0005737=GO_REF:0000019, GO:0000185=GO_REF:0000019, GO:0005887=PMID:7908515, GO:0043198=GO_REF:0000019, GO:0040013=GO_REF:0000019, GO:0002029=GO_REF:0000019, GO:0008066=PMID:7908515, GO:0006468=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0007612=GO_REF:0000019, GO:0048170=GO_REF:0000019} Q6J164 Metabotropic glutamate receptor 5 protein 20130413 {GO:0006355=IEA, GO:0005886=IEA, GO:0004930=IEA, GO:0031687=IEA, GO:0007268=IEA, GO:0014069=IEA, GO:0007205=IEA, GO:0007206=TAS, GO:0005737=IEA, GO:0000185=IEA, GO:0005887=TAS, GO:0043198=IEA, GO:0040013=IEA, GO:0002029=IEA, GO:0008066=TAS, GO:0006468=IEA, GO:0007626=IEA, GO:0016021=IEA, GO:0007612=IEA, GO:0048170=IEA} activation of MAPKKK activity, desensitization of G-protein coupled receptor protein signaling pathway, learning, locomotory behavior, negative regulation of locomotion, phospholipase C-activating G-protein coupled glutamate receptor signaling pathway, positive regulation of long-term neuronal synaptic plasticity, protein kinase C-activating G-protein coupled receptor signaling pathway, protein phosphorylation, regulation of transcription, DNA-dependent, synaptic transmission cytoplasm, dendritic shaft, integral to membrane, integral to plasma membrane, plasma membrane, postsynaptic density A2A adenosine receptor binding, G-protein coupled receptor activity, glutamate receptor activity Human UniProtKB-SubCell:SL-0039 GRM6 Reactome UniProtKB {GO:0009584=PMID:9215706, GO:0005886=Reactome:REACT_18380, GO:0060041=GO_REF:0000019, GO:0005887=PMID:9215706, GO:0004930=PMID:9215706, GO:0035841=GO_REF:0000019, GO:0001640=GO_REF:0000019, GO:0008066=PMID:9215706, GO:0007216=PMID:9215706, GO:0007268=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0007601=GO_REF:0000037} O15303 Metabotropic glutamate receptor 6 protein 20090512 {GO:0009584=TAS, GO:0005886=TAS, GO:0060041=IEA, GO:0005887=TAS, GO:0004930=TAS, GO:0035841=IEA, GO:0001640=IEA, GO:0008066=TAS, GO:0007216=TAS, GO:0007268=IEA, GO:0007626=IEA, GO:0007601=IEA} G-protein coupled glutamate receptor signaling pathway, detection of visible light, locomotory behavior, retina development in camera-type eye, synaptic transmission, visual perception integral to plasma membrane, new growing cell tip, plasma membrane G-protein coupled receptor activity, adenylate cyclase inhibiting G-protein coupled glutamate receptor activity, glutamate receptor activity Human GRM7 Reactome UniProtKB {GO:0030424=GO_REF:0000024, GO:0007608=GO_REF:0000037, GO:0005886=Reactome:REACT_18380, GO:0007605=PMID:19047183, GO:0030818=PMID:9473604, GO:0014050=GO_REF:0000024, GO:0007268=PMID:9473604, GO:0007194=PMID:9473604, GO:0010855=PMID:9473604, GO:0030425=PMID:9630572, GO:0032279=GO_REF:0000024, GO:0043198=GO_REF:0000024, GO:0045211=GO_REF:0000024, GO:0030534=GO_REF:0000019, GO:0001662=PMID:17167337, GO:0001661=GO_REF:0000019, GO:0070905=PMID:9144652, GO:0005938=PMID:9630572, GO:0048786=GO_REF:0000024, GO:0005245=GO_REF:0000019, GO:0004930=GO_REF:0000038, GO:0005246=GO_REF:0000019, GO:0007614=GO_REF:0000019, GO:0001642=PMID:9473604, GO:0042734=GO_REF:0000019, GO:0007186=GO_REF:0000002, GO:0005887=PMID:9473604, GO:0008066=PMID:9473604, GO:0016595=PMID:9473604, GO:0016021=PMID:12746871} Q14831 Metabotropic glutamate receptor 7 protein 20090512 {GO:0030424=ISS, GO:0007608=IEA, GO:0005886=TAS, GO:0007605=IMP, GO:0030818=IDA, GO:0014050=ISS, GO:0007268=IDA, GO:0007194=IDA, GO:0010855=IDA, GO:0030425=IDA, GO:0032279=ISS, GO:0043198=ISS, GO:0045211=ISS, GO:0030534=IEA, GO:0001662=IMP, GO:0001661=IEA, GO:0070905=IDA, GO:0005938=IDA, GO:0048786=ISS, GO:0005245=IEA, GO:0004930=IEA, GO:0005246=IEA, GO:0007614=IEA, GO:0001642=IDA, GO:0042734=IEA, GO:0007186=IEA, GO:0005887=NAS, GO:0008066=IDA, GO:0016595=IDA, GO:0016021=IDA} G-protein coupled receptor signaling pathway, adult behavior, behavioral fear response, conditioned taste aversion, negative regulation of adenylate cyclase activity, negative regulation of cAMP biosynthetic process, negative regulation of glutamate secretion, sensory perception of smell, sensory perception of sound, short-term memory, synaptic transmission asymmetric synapse, axon, cell cortex, dendrite, dendritic shaft, integral to membrane, integral to plasma membrane, plasma membrane, postsynaptic membrane, presynaptic active zone, presynaptic membrane G-protein coupled receptor activity, adenylate cyclase inhibitor activity, calcium channel regulator activity, glutamate binding, glutamate receptor activity, group III metabotropic glutamate receptor activity, serine binding, voltage-gated calcium channel activity Human GRM8 Reactome UniProtKB {GO:0007608=GO_REF:0000037, GO:0005886=Reactome:REACT_18380, GO:0005887=PMID:9473604, GO:0004930=PMID:9473604, GO:0030818=PMID:11166323, GO:0008066=PMID:9473604, GO:0001642=GO_REF:0000019, GO:0016021=GO_REF:0000002, GO:0007194=PMID:9473604, GO:0007601=PMID:9473604} O00222 Metabotropic glutamate receptor 8 protein 20090512 {GO:0007608=IEA, GO:0005886=TAS, GO:0005887=TAS, GO:0004930=TAS, GO:0030818=IDA, GO:0008066=TAS, GO:0001642=IEA, GO:0016021=IEA, GO:0007194=TAS, GO:0007601=TAS} negative regulation of adenylate cyclase activity, negative regulation of cAMP biosynthetic process, sensory perception of smell, visual perception integral to membrane, integral to plasma membrane, plasma membrane G-protein coupled receptor activity, glutamate receptor activity, group III metabotropic glutamate receptor activity Human GRN HPA UniProtKB {GO:0005515=PMID:23088713, GO:0050679=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0007165=PMID:1542665, GO:0008219=GO_REF:0000037, GO:0007566=GO_REF:0000019, GO:0001835=GO_REF:0000019, GO:0008083=PMID:1542665, GO:0005615=GO_REF:0000019, GO:0005125=GO_REF:0000037, GO:0043231=GO_REF:0000052} P28799 Granulins protein 20111111 {GO:0005515=IPI, GO:0050679=IEA, GO:0005739=IEA, GO:0007165=NAS, GO:0008219=IEA, GO:0007566=IEA, GO:0001835=IEA, GO:0008083=TAS, GO:0005615=IEA, GO:0005125=IEA, GO:0043231=IDA} blastocyst hatching, cell death, embryo implantation, positive regulation of epithelial cell proliferation, signal transduction extracellular space, intracellular membrane-bounded organelle, mitochondrion cytokine activity, growth factor activity, protein binding Human GRP Reactome UniProtKB {GO:0007165=PMID:3027901, GO:0007218=PMID:8756537, GO:0005102=PMID:3027901, GO:0005576=Reactome:REACT_22436, GO:0005184=PMID:8756537, GO:0005615=PMID:8756537} P07492 Gastrin-releasing peptide protein 20080826 {GO:0007165=NAS, GO:0007218=IDA, GO:0005102=NAS, GO:0005576=TAS, GO:0005184=IDA, GO:0005615=IDA} neuropeptide signaling pathway, signal transduction extracellular region, extracellular space neuropeptide hormone activity, receptor binding Human GRPEL1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0006457=GO_REF:0000002, GO:0005759=PMID:11311562, GO:0006626=Reactome:REACT_118595, GO:0051087=GO_REF:0000002, GO:0051082=PMID:11311562, GO:0030150=GO_REF:0000029, GO:0044267=Reactome:REACT_17015, GO:0042803=GO_REF:0000002, GO:0000774=GO_REF:0000002} Q9HAV7 GrpE protein homolog 1, mitochondrial protein 20110516 {GO:0005739=IDA, GO:0006457=IEA, GO:0005759=IDA, GO:0006626=TAS, GO:0051087=IEA, GO:0051082=IDA, GO:0030150=NAS, GO:0044267=TAS, GO:0042803=IEA, GO:0000774=IEA} cellular protein metabolic process, protein folding, protein import into mitochondrial matrix, protein targeting to mitochondrion mitochondrial matrix, mitochondrion adenyl-nucleotide exchange factor activity, chaperone binding, protein homodimerization activity, unfolded protein binding Human GRPEL2 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0006457=GO_REF:0000002, GO:0005759=GO_REF:0000039, GO:0006626=Reactome:REACT_118595, GO:0005743=GO_REF:0000019, GO:0051087=GO_REF:0000002, GO:0051082=GO_REF:0000019, GO:0044267=Reactome:REACT_17015, GO:0042803=GO_REF:0000002, GO:0000774=GO_REF:0000002} Q8TAA5 GrpE protein homolog 2, mitochondrial protein 20090616 {GO:0005739=IDA, GO:0005737=IDA, GO:0006457=IEA, GO:0005759=IEA, GO:0006626=TAS, GO:0005743=IEA, GO:0051087=IEA, GO:0051082=IEA, GO:0044267=TAS, GO:0042803=IEA, GO:0000774=IEA} cellular protein metabolic process, protein folding, protein targeting to mitochondrion cytoplasm, mitochondrial inner membrane, mitochondrial matrix, mitochondrion adenyl-nucleotide exchange factor activity, chaperone binding, protein homodimerization activity, unfolded protein binding Human GRPR Reactome UniProtKB {GO:0004946=GO_REF:0000002, GO:0005886=Reactome:REACT_22436, GO:0007186=PMID:1655761, GO:0005887=PMID:8391296, GO:0008283=PMID:1655761, GO:0042127=GO_REF:0000019, GO:0008528=PMID:7838118} P30550 Gastrin-releasing peptide receptor protein 20080826 {GO:0004946=IEA, GO:0005886=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0008283=TAS, GO:0042127=IEA, GO:0008528=TAS} G-protein coupled receptor signaling pathway, cell proliferation, regulation of cell proliferation integral to plasma membrane, plasma membrane G-protein coupled peptide receptor activity, bombesin receptor activity Human GRSF1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0006378=PMID:8036161, GO:0005737=PMID:8036161, GO:0016331=GO_REF:0000019, GO:0000166=GO_REF:0000002, GO:0003723=PMID:8036161, GO:0003729=PMID:8036161, GO:0009952=GO_REF:0000019, GO:0003676=GO_REF:0000002} Q12849 G-rich sequence factor 1 protein 20110516 {GO:0005739=IDA, GO:0006378=TAS, GO:0005737=TAS, GO:0016331=IEA, GO:0000166=IEA, GO:0003723=TAS, GO:0003729=TAS, GO:0009952=IEA, GO:0003676=IEA} anterior/posterior pattern specification, mRNA polyadenylation, morphogenesis of embryonic epithelium cytoplasm, mitochondrion RNA binding, mRNA binding, nucleic acid binding, nucleotide binding Human GRTP1 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0005097=GO_REF:0000002} Q5TC63 Growth hormone-regulated TBC protein 1 protein 20130413 {GO:0005622=IEA, GO:0005097=IEA} intracellular Rab GTPase activator activity Human InterPro:IPR000195 GRWD1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9BQ67 Glutamate-rich WD repeat-containing protein 1 protein 20111111 {GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA} cytoplasm, nucleolus, nucleus Human GRXCR1 UniProtKB UniProtKB {GO:0060122=GO_REF:0000024, GO:0042491=GO_REF:0000019, GO:0007605=GO_REF:0000024, GO:0015035=GO_REF:0000002, GO:0048563=GO_REF:0000019, GO:0060118=GO_REF:0000024, GO:0009055=GO_REF:0000002, GO:0060119=GO_REF:0000024, GO:0032420=GO_REF:0000024, GO:0060091=GO_REF:0000024, GO:0003674=GO_REF:0000015, GO:0010923=PMID:19389623, GO:0045454=GO_REF:0000002} A8MXD5 Glutaredoxin domain-containing cysteine-rich protein 1 protein 20111103 {GO:0060122=ISS, GO:0042491=IEA, GO:0007605=ISS, GO:0015035=IEA, GO:0048563=IEA, GO:0060118=ISS, GO:0009055=IEA, GO:0060119=ISS, GO:0032420=ISS, GO:0060091=ISS, GO:0003674=ND, GO:0010923=IDA, GO:0045454=IEA} auditory receptor cell differentiation, cell redox homeostasis, inner ear receptor cell development, inner ear receptor stereocilium organization, negative regulation of phosphatase activity, post-embryonic organ morphogenesis, sensory perception of sound, vestibular receptor cell development kinocilium, stereocilium electron carrier activity, molecular_function, protein disulfide oxidoreductase activity Human GSC BHF-UCL UniProtKB {GO:0001103=GO_REF:0000024, GO:0005667=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0007369=PMID:7916327, GO:0023019=GO_REF:0000019, GO:0030178=GO_REF:0000019, GO:0048704=GO_REF:0000019, GO:0005634=GO_REF:0000029, GO:0000122=GO_REF:0000019, GO:0003677=GO_REF:0000029, GO:0043565=GO_REF:0000002, GO:0048644=GO_REF:0000019, GO:0001085=GO_REF:0000024, GO:0042474=GO_REF:0000024, GO:0021904=GO_REF:0000019, GO:0030900=GO_REF:0000019} P56915 Homeobox protein goosecoid protein 20121106 {GO:0001103=ISS, GO:0005667=IEA, GO:0003700=IEA, GO:0007369=NAS, GO:0023019=IEA, GO:0030178=IEA, GO:0048704=IEA, GO:0005634=NAS, GO:0000122=IEA, GO:0003677=NAS, GO:0043565=IEA, GO:0048644=IEA, GO:0001085=ISS, GO:0042474=ISS, GO:0021904=IEA, GO:0030900=IEA} dorsal/ventral neural tube patterning, embryonic skeletal system morphogenesis, forebrain development, gastrulation, middle ear morphogenesis, muscle organ morphogenesis, negative regulation of Wnt receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, signal transduction involved in regulation of gene expression nucleus, transcription factor complex DNA binding, RNA polymerase II repressing transcription factor binding, RNA polymerase II transcription factor binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:Q02591 GSC2 MGI UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=PMID:9700206, GO:0006357=PMID:9700206, GO:0005634=GO_REF:0000039, GO:0003677=PMID:9441739, GO:0009653=PMID:9150167} O15499 Homeobox protein goosecoid-2 protein 20080403 {GO:0043565=IEA, GO:0003700=IDA, GO:0006357=IDA, GO:0005634=IEA, GO:0003677=TAS, GO:0009653=TAS} anatomical structure morphogenesis, regulation of transcription from RNA polymerase II promoter nucleus DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human GSDMA UniProtKB UniProtKB {GO:0048471=PMID:17471240, GO:0006915=GO_REF:0000037, GO:0006917=PMID:17471240} Q96QA5 Gasdermin-A protein 20080708 {GO:0048471=IDA, GO:0006915=IEA, GO:0006917=IDA} apoptotic process, induction of apoptosis perinuclear region of cytoplasm Human GSDMB UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q8TAX9 Gasdermin-B protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 GSDMD ENSEMBL UniProtKB {GO:0031668=GO_REF:0000019} P57764 Gasdermin-D protein 20130413 {GO:0031668=IEA} cellular response to extracellular stimulus Human Ensembl:ENSMUSP00000023238 GSG2 HPA UniProtKB {GO:0005515=PMID:22939624, GO:0090231=PMID:20705812, GO:0031965=GO_REF:0000052, GO:0005813=PMID:11228240, GO:0005694=GO_REF:0000039, GO:0005819=PMID:15681610, GO:0005634=GO_REF:0000052, GO:0071459=PMID:20705812, GO:0003677=GO_REF:0000019, GO:0005524=PMID:11228240, GO:0007243=PMID:11228240, GO:0043231=GO_REF:0000052, GO:0072354=PMID:15681610, GO:0005737=GO_REF:0000052, GO:0004672=PMID:11228240, GO:2000751=PMID:23071153, GO:0006468=PMID:11228240, GO:0007064=PMID:20705812} Q8TF76 Serine/threonine-protein kinase haspin protein 20111111 {GO:0005515=IPI, GO:0090231=IMP, GO:0031965=IDA, GO:0005813=IDA, GO:0005694=IEA, GO:0005819=IDA, GO:0005634=IDA, GO:0071459=IMP, GO:0003677=IEA, GO:0005524=IDA, GO:0007243=IDA, GO:0043231=IDA, GO:0072354=IMP, GO:0005737=IDA, GO:0004672=IDA, GO:2000751=IMP, GO:0006468=IDA, GO:0007064=IMP} histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore, intracellular protein kinase cascade, mitotic sister chromatid cohesion, protein localization to chromosome, centromeric region, protein phosphorylation, regulation of spindle checkpoint centrosome, chromosome, cytoplasm, intracellular membrane-bounded organelle, nuclear membrane, nucleus, spindle ATP binding, DNA binding, histone kinase activity (H3-T3 specific), protein binding, protein kinase activity Human GSK3A BHF-UCL UniProtKB {GO:0034236=PMID:11035810, GO:0005515=PMID:16365045, GO:0008286=PMID:18285345, GO:0032007=GO_REF:0000024, GO:0045732=PMID:19759537, GO:0030819=GO_REF:0000024, GO:0030877=PMID:19759537, GO:0050321=PMID:19366350, GO:0003214=GO_REF:0000024, GO:0010905=PMID:11035810, GO:0030968=Reactome:REACT_18356, GO:0005829=PMID:11035810, GO:0007173=Reactome:REACT_9417, GO:0046325=PMID:17569761, GO:0016055=GO_REF:0000037, GO:0090090=PMID:19366350, GO:0045823=GO_REF:0000024, GO:2000467=GO_REF:0000024, GO:2000466=PMID:19366350, GO:0032869=PMID:17569761, GO:0048011=Reactome:REACT_11061, GO:0048015=Reactome:REACT_12464, GO:0046627=PMID:17569761, GO:0005977=GO_REF:0000037, GO:0051348=PMID:17569761, GO:0005524=GO_REF:0000037, GO:0045719=PMID:19366350, GO:0007399=GO_REF:0000037, GO:0003073=GO_REF:0000024, GO:0061052=GO_REF:0000024, GO:0004674=PMID:11035810, GO:0008543=Reactome:REACT_9470, GO:2000077=PMID:19366350, GO:0045087=Reactome:REACT_6802, GO:0006468=PMID:11035810, GO:0006987=Reactome:REACT_18368, GO:0071879=GO_REF:0000024, GO:0044267=Reactome:REACT_17015} P49840 Glycogen synthase kinase-3 alpha protein 20100930 {GO:0034236=IPI, GO:0005515=IPI, GO:0008286=ISS, GO:0032007=ISS, GO:0045732=NAS, GO:0030819=ISS, GO:0030877=NAS, GO:0050321=TAS, GO:0003214=ISS, GO:0010905=IC, GO:0030968=TAS, GO:0005829=TAS, GO:0007173=TAS, GO:0046325=IMP, GO:0016055=IEA, GO:0090090=TAS, GO:0045823=ISS, GO:2000467=ISS, GO:2000466=TAS, GO:0032869=IMP, GO:0048011=TAS, GO:0048015=TAS, GO:0046627=IMP, GO:0005977=IEA, GO:0051348=IMP, GO:0005524=IEA, GO:0045719=TAS, GO:0007399=IEA, GO:0003073=ISS, GO:0061052=ISS, GO:0004674=IDA, GO:0008543=TAS, GO:2000077=TAS, GO:0045087=TAS, GO:0006468=IDA, GO:0006987=TAS, GO:0071879=ISS, GO:0044267=TAS} Wnt receptor signaling pathway, activation of signaling protein activity involved in unfolded protein response, cardiac left ventricle morphogenesis, cellular protein metabolic process, cellular response to insulin stimulus, endoplasmic reticulum unfolded protein response, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, glycogen metabolic process, innate immune response, insulin receptor signaling pathway, negative regulation of TOR signaling cascade, negative regulation of UDP-glucose catabolic process, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cell growth involved in cardiac muscle cell development, negative regulation of glucose import, negative regulation of glycogen (starch) synthase activity, negative regulation of glycogen biosynthetic process, negative regulation of insulin receptor signaling pathway, negative regulation of transferase activity, negative regulation of type B pancreatic cell development, nervous system development, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of adrenergic receptor signaling pathway, positive regulation of cAMP biosynthetic process, positive regulation of glycogen (starch) synthase activity, positive regulation of heart contraction, positive regulation of protein catabolic process, protein phosphorylation, regulation of systemic arterial blood pressure beta-catenin destruction complex, cytosol ATP binding, protein binding, protein kinase A catalytic subunit binding, protein serine/threonine kinase activity, tau-protein kinase activity Human UniProtKB:O75581 GSK3B BHF-UCL UniProtKB {GO:0005515=PMID:16365045, GO:0006983=PMID:14744935, GO:0008013=PMID:8638126, GO:0050321=PMID:16365045, GO:0030877=PMID:16188939, GO:0035372=GO_REF:0000019, GO:0030010=GO_REF:0000019, GO:0032855=PMID:18156211, GO:0044027=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0018105=PMID:8638126, GO:0048168=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0016301=Reactome:REACT_9987, GO:0006611=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0045444=GO_REF:0000019, GO:0009887=GO_REF:0000019, GO:0031625=PMID:21118991, GO:0010800=GO_REF:0000019, GO:2000466=PMID:19366350, GO:0005813=PMID:21399614, GO:0071109=PMID:19581563, GO:0019901=PMID:18348280, GO:0005977=PMID:8638126, GO:0007520=GO_REF:0000019, GO:0005178=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:2000077=PMID:19366350, GO:0007623=GO_REF:0000024, GO:0050774=GO_REF:0000019, GO:0045121=GO_REF:0000019, GO:0045892=GO_REF:0000019, GO:0001954=PMID:18156211, GO:0034236=PMID:11035810, GO:0045732=PMID:16188939, GO:0048471=GO_REF:0000019, GO:0005886=PMID:20937854, GO:0044337=GO_REF:0000019, GO:2000738=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0001837=PMID:15448698, GO:0005829=Reactome:REACT_147823, GO:0032092=GO_REF:0000024, GO:0030426=GO_REF:0000019, GO:0046827=PMID:14744935, GO:0035556=PMID:14749367, GO:0002039=PMID:14744935, GO:0033138=GO_REF:0000019, GO:0005737=PMID:19038973, GO:0031334=PMID:8638126, GO:0031333=PMID:16188939, GO:0043197=GO_REF:0000019, GO:0043198=GO_REF:0000019, GO:0043407=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0001085=PMID:20864106, GO:0060070=PMID:18787224, GO:0090090=PMID:19366350, GO:0000320=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0043066=PMID:14744935, GO:0051059=PMID:15465828, GO:0048015=Reactome:REACT_12464, GO:0042493=GO_REF:0000019, GO:0051534=PMID:9072970, GO:0005730=GO_REF:0000052, GO:0048156=GO_REF:0000019, GO:0032886=PMID:20937854, GO:0005524=GO_REF:0000019, GO:0045719=PMID:19366350, GO:0021766=PMID:19581563, GO:0010226=GO_REF:0000019, GO:0035255=GO_REF:0000019, GO:0016477=GO_REF:0000019, GO:0004674=GO_REF:0000024, GO:0030529=GO_REF:0000019, GO:0006349=GO_REF:0000019, GO:0006468=PMID:11035810} P49841 Glycogen synthase kinase-3 beta protein 20100818 {GO:0005515=IPI, GO:0006983=IDA, GO:0008013=IPI, GO:0050321=IDA, GO:0030877=IDA, GO:0035372=IEA, GO:0030010=IEA, GO:0032855=IMP, GO:0044027=IEA, GO:0007173=TAS, GO:0018105=IDA, GO:0048168=IEA, GO:0007411=TAS, GO:0016301=TAS, GO:0006611=IEA, GO:0043025=IEA, GO:0045444=IEA, GO:0009887=IEA, GO:0031625=IPI, GO:0010800=IEA, GO:2000466=TAS, GO:0005813=IDA, GO:0071109=IMP, GO:0019901=IPI, GO:0005977=IDA, GO:0007520=IEA, GO:0005178=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:2000077=TAS, GO:0007623=ISS, GO:0050774=IEA, GO:0045121=IEA, GO:0045892=IEA, GO:0001954=IMP, GO:0034236=IPI, GO:0045732=IC, GO:0048471=IEA, GO:0005886=IDA, GO:0044337=IEA, GO:2000738=IEA, GO:0005634=IDA, GO:0001837=IMP, GO:0005829=TAS, GO:0032092=ISS, GO:0030426=IEA, GO:0046827=IDA, GO:0035556=IDA, GO:0002039=IDA, GO:0033138=IEA, GO:0005737=IDA, GO:0031334=IDA, GO:0031333=IMP, GO:0043197=IEA, GO:0043198=IEA, GO:0043407=IEA, GO:0045944=IEA, GO:0001085=IPI, GO:0060070=IDA, GO:0090090=TAS, GO:0000320=IEA, GO:0048011=TAS, GO:0043066=IDA, GO:0051059=IPI, GO:0048015=TAS, GO:0042493=IEA, GO:0051534=IMP, GO:0005730=IDA, GO:0048156=IEA, GO:0032886=IMP, GO:0005524=IEA, GO:0045719=TAS, GO:0021766=IMP, GO:0010226=IEA, GO:0035255=IEA, GO:0016477=IEA, GO:0004674=ISS, GO:0030529=IEA, GO:0006349=IEA, GO:0006468=IDA} ER overload response, axon guidance, canonical Wnt receptor signaling pathway, canonical Wnt receptor signaling pathway involved in positive regulation of apoptotic process, cell migration, circadian rhythm, epidermal growth factor receptor signaling pathway, epithelial to mesenchymal transition, establishment of cell polarity, fat cell differentiation, fibroblast growth factor receptor signaling pathway, glycogen metabolic process, hippocampus development, hypermethylation of CpG island, innate immune response, intracellular signal transduction, myoblast fusion, negative regulation of MAP kinase activity, negative regulation of NFAT protein import into nucleus, negative regulation of apoptotic process, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of dendrite morphogenesis, negative regulation of glycogen (starch) synthase activity, negative regulation of glycogen biosynthetic process, negative regulation of protein complex assembly, negative regulation of transcription, DNA-dependent, negative regulation of type B pancreatic cell development, neurotrophin TRK receptor signaling pathway, organ morphogenesis, peptidyl-serine phosphorylation, phosphatidylinositol-mediated signaling, positive regulation of Rac GTPase activity, positive regulation of cell-matrix adhesion, positive regulation of peptidyl-serine phosphorylation, positive regulation of peptidyl-threonine phosphorylation, positive regulation of protein binding, positive regulation of protein catabolic process, positive regulation of protein complex assembly, positive regulation of protein export from nucleus, positive regulation of stem cell differentiation, positive regulation of transcription from RNA polymerase II promoter, protein export from nucleus, protein localization to microtubule, protein phosphorylation, re-entry into mitotic cell cycle, regulation of gene expression by genetic imprinting, regulation of microtubule-based process, regulation of neuronal synaptic plasticity, response to drug, response to lithium ion, superior temporal gyrus development beta-catenin destruction complex, centrosome, cytoplasm, cytosol, dendritic shaft, dendritic spine, growth cone, membrane raft, neuronal cell body, nucleolus, nucleus, perinuclear region of cytoplasm, plasma membrane, ribonucleoprotein complex ATP binding, NF-kappaB binding, RNA polymerase II transcription factor binding, beta-catenin binding, integrin binding, ionotropic glutamate receptor binding, kinase activity, p53 binding, protein binding, protein kinase A catalytic subunit binding, protein kinase binding, protein serine/threonine kinase activity, tau protein binding, tau-protein kinase activity, ubiquitin protein ligase binding Human GSN InterPro UniProtKB {GO:0005515=PMID:10793131, GO:0048471=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0042246=GO_REF:0000019, GO:0015629=GO_REF:0000019, GO:0030155=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_13795, GO:0051014=GO_REF:0000024, GO:0051016=PMID:1321812, GO:0030041=GO_REF:0000024, GO:0071276=GO_REF:0000019, GO:0016192=GO_REF:0000019, GO:0048015=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0005509=PMID:1321812, GO:0006915=GO_REF:0000019, GO:0003779=GO_REF:0000002, GO:0005576=Reactome:REACT_75905, GO:0001726=GO_REF:0000019, GO:0030027=GO_REF:0000019, GO:0051593=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0008154=GO_REF:0000019, GO:0014003=GO_REF:0000019, GO:0060271=PMID:20393563} Q5T0I1 Gelsolin protein 20130413 {GO:0005515=IPI, GO:0048471=IEA, GO:0045471=IEA, GO:0042246=IEA, GO:0015629=IEA, GO:0030155=IEA, GO:0005615=IEA, GO:0006921=TAS, GO:0005829=TAS, GO:0051014=ISS, GO:0051016=TAS, GO:0030041=ISS, GO:0071276=IEA, GO:0016192=IEA, GO:0048015=IEA, GO:0007568=IEA, GO:0005509=TAS, GO:0006915=IEA, GO:0003779=IEA, GO:0005576=TAS, GO:0001726=IEA, GO:0030027=IEA, GO:0051593=IEA, GO:0043234=IEA, GO:0008154=IEA, GO:0014003=IEA, GO:0060271=IMP} actin filament polymerization, actin filament severing, actin polymerization or depolymerization, aging, apoptotic process, barbed-end actin filament capping, cellular component disassembly involved in execution phase of apoptosis, cellular response to cadmium ion, cilium morphogenesis, oligodendrocyte development, phosphatidylinositol-mediated signaling, regulation of cell adhesion, response to ethanol, response to folic acid, tissue regeneration, vesicle-mediated transport actin cytoskeleton, cytosol, extracellular region, extracellular space, lamellipodium, perinuclear region of cytoplasm, protein complex, ruffle actin binding, calcium ion binding, protein binding Human InterPro:IPR007122 GSPT1 GOC UniProtKB {GO:0006184=PMID:15326224, GO:0005622=PMID:15326224, GO:0005515=PMID:9712840, GO:0000082=PMID:2511002, GO:0000184=PMID:15326224, GO:0006479=PMID:18539146, GO:0003924=PMID:15326224, GO:0005525=GO_REF:0000037, GO:0003747=PMID:15326224} P15170 Eukaryotic peptide chain release factor GTP-binding subunit ERF3A protein 20130413 {GO:0006184=TAS, GO:0005622=NAS, GO:0005515=IPI, GO:0000082=TAS, GO:0000184=TAS, GO:0006479=IDA, GO:0003924=TAS, GO:0005525=IEA, GO:0003747=IMP} G1/S transition of mitotic cell cycle, GTP catabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, protein methylation intracellular GTP binding, GTPase activity, protein binding, translation release factor activity Human GSPT2 IntAct UniProtKB {GO:0005515=PMID:18447585, GO:0010467=Reactome:REACT_71, GO:0007049=GO_REF:0000037, GO:0016070=Reactome:REACT_21257, GO:0000184=Reactome:REACT_75886, GO:0016071=Reactome:REACT_20605, GO:0003924=GO_REF:0000002, GO:0006415=Reactome:REACT_1986, GO:0005525=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0005829=Reactome:REACT_75917} Q8IYD1 Eukaryotic peptide chain release factor GTP-binding subunit ERF3B protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0007049=IEA, GO:0016070=TAS, GO:0000184=TAS, GO:0016071=TAS, GO:0003924=IEA, GO:0006415=TAS, GO:0005525=IEA, GO:0044267=TAS, GO:0006412=TAS, GO:0005829=TAS} RNA metabolic process, cell cycle, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational termination cytosol GTP binding, GTPase activity, protein binding Human UniProtKB:Q92900 GSR Reactome UniProtKB {GO:0050661=GO_REF:0000002, GO:0005739=GO_REF:0000039, GO:0016668=GO_REF:0000002, GO:0015949=Reactome:REACT_21330, GO:0050660=GO_REF:0000002, GO:0009055=PMID:947404, GO:0006749=GO_REF:0000002, GO:0055086=Reactome:REACT_1698, GO:0045454=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0004362=Reactome:REACT_2220, GO:0005829=Reactome:REACT_2220} P00390 Glutathione reductase, mitochondrial protein 20130213 {GO:0050661=IEA, GO:0005739=IEA, GO:0016668=IEA, GO:0015949=TAS, GO:0050660=IEA, GO:0009055=TAS, GO:0006749=IEA, GO:0055086=TAS, GO:0045454=IEA, GO:0044281=TAS, GO:0004362=TAS, GO:0005829=TAS} cell redox homeostasis, glutathione metabolic process, nucleobase-containing small molecule interconversion, nucleobase-containing small molecule metabolic process, small molecule metabolic process cytosol, mitochondrion NADP binding, electron carrier activity, flavin adenine dinucleotide binding, glutathione-disulfide reductase activity, oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor Human GSS Reactome UniProtKB {GO:0006520=PMID:8896573, GO:0042277=GO_REF:0000019, GO:0006805=Reactome:REACT_13433, GO:0000287=PMID:10369661, GO:0007568=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0004363=Reactome:REACT_6886, GO:0005524=PMID:10369661, GO:0042803=PMID:10369661, GO:0005829=Reactome:REACT_6886, GO:0007399=PMID:8896573, GO:0043295=PMID:10369661, GO:0006750=Reactome:REACT_6960, GO:0016594=GO_REF:0000019, GO:0031667=GO_REF:0000019, GO:0034612=GO_REF:0000019, GO:0009410=GO_REF:0000019, GO:0006979=PMID:465367, GO:0043200=GO_REF:0000019, GO:0046686=GO_REF:0000019} P48637 Glutathione synthetase protein 20130213 {GO:0006520=TAS, GO:0042277=IEA, GO:0006805=TAS, GO:0000287=IDA, GO:0007568=IEA, GO:0044281=TAS, GO:0004363=TAS, GO:0005524=IDA, GO:0042803=IDA, GO:0005829=TAS, GO:0007399=TAS, GO:0043295=IDA, GO:0006750=TAS, GO:0016594=IEA, GO:0031667=IEA, GO:0034612=IEA, GO:0009410=IEA, GO:0006979=TAS, GO:0043200=IEA, GO:0046686=IEA} aging, cellular amino acid metabolic process, glutathione biosynthetic process, nervous system development, response to amino acid stimulus, response to cadmium ion, response to nutrient levels, response to oxidative stress, response to tumor necrosis factor, response to xenobiotic stimulus, small molecule metabolic process, xenobiotic metabolic process cytosol ATP binding, glutathione binding, glutathione synthase activity, glycine binding, magnesium ion binding, peptide binding, protein homodimerization activity Human GSTA1 Reactome UniProtKB {GO:0005737=GO_REF:0000029, GO:0006805=Reactome:REACT_13433, GO:0008152=PMID:3800996, GO:0006749=PMID:11851347, GO:0044281=Reactome:REACT_111217, GO:0004364=PMID:11851347, GO:0005829=Reactome:REACT_6854} P08263 Glutathione S-transferase A1 protein 20130301 {GO:0005737=NAS, GO:0006805=TAS, GO:0008152=IC, GO:0006749=IDA, GO:0044281=TAS, GO:0004364=IDA, GO:0005829=TAS} glutathione metabolic process, metabolic process, small molecule metabolic process, xenobiotic metabolic process cytoplasm, cytosol glutathione transferase activity Human GSTA2 Reactome UniProtKB {GO:0006805=Reactome:REACT_13433, GO:0006749=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0004364=GO_REF:0000024, GO:0005829=Reactome:REACT_6854} P09210 Glutathione S-transferase A2 protein 20130301 {GO:0006805=TAS, GO:0006749=ISS, GO:0044281=TAS, GO:0004364=ISS, GO:0005829=TAS} glutathione metabolic process, small molecule metabolic process, xenobiotic metabolic process cytosol glutathione transferase activity Human GSTA3 UniProtKB UniProtKB {GO:0006805=Reactome:REACT_13433, GO:0006749=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0004364=GO_REF:0000003, GO:0005829=Reactome:REACT_6854} Q5JW85 Glutathione S-transferase protein 20130413 {GO:0006805=TAS, GO:0006749=ISS, GO:0044281=TAS, GO:0004364=IEA, GO:0005829=TAS} glutathione metabolic process, small molecule metabolic process, xenobiotic metabolic process cytosol glutathione transferase activity Human EC:2.5.1.18 GSTA4 UniProtKB UniProtKB {GO:0006805=Reactome:REACT_13433, GO:0006749=PMID:10329152, GO:0044281=Reactome:REACT_111217, GO:0004364=GO_REF:0000003, GO:0042803=PMID:10329152, GO:0005829=Reactome:REACT_6854} Q6P4G1 Glutathione S-transferase protein 20130413 {GO:0006805=TAS, GO:0006749=IDA, GO:0044281=TAS, GO:0004364=IEA, GO:0042803=IPI, GO:0005829=TAS} glutathione metabolic process, small molecule metabolic process, xenobiotic metabolic process cytosol glutathione transferase activity, protein homodimerization activity Human EC:2.5.1.18 GSTA5 Reactome UniProtKB {GO:0006805=Reactome:REACT_13433, GO:0006749=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0004364=GO_REF:0000024, GO:0005829=Reactome:REACT_6854} Q7RTV2 Glutathione S-transferase A5 protein 20130301 {GO:0006805=TAS, GO:0006749=ISS, GO:0044281=TAS, GO:0004364=ISS, GO:0005829=TAS} glutathione metabolic process, small molecule metabolic process, xenobiotic metabolic process cytosol glutathione transferase activity Human GSTCD BHF-UCL UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q8NEC7 Glutathione S-transferase C-terminal domain-containing protein protein 20111130 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human GSTK1 HPA UniProtKB {GO:0005622=GO_REF:0000054, GO:0004602=PMID:14742434, GO:0005759=GO_REF:0000019, GO:0005102=PMID:20178365, GO:0005743=GO_REF:0000019, GO:0015035=GO_REF:0000002, GO:0006749=GO_REF:0000019, GO:0004364=PMID:14742434, GO:0005777=PMID:14742434, GO:0043231=GO_REF:0000052} Q9Y2Q3 Glutathione S-transferase kappa 1 protein 20101115 {GO:0005622=IDA, GO:0004602=IDA, GO:0005759=IEA, GO:0005102=IPI, GO:0005743=IEA, GO:0015035=IEA, GO:0006749=IEA, GO:0004364=IDA, GO:0005777=IDA, GO:0043231=IDA} glutathione metabolic process intracellular, intracellular membrane-bounded organelle, mitochondrial inner membrane, mitochondrial matrix, peroxisome glutathione peroxidase activity, glutathione transferase activity, protein disulfide oxidoreductase activity, receptor binding Human GSTM1 BHF-UCL UniProtKB {GO:0043295=PMID:8373352, GO:0005737=PMID:8373352, GO:0006805=Reactome:REACT_13433, GO:0018916=PMID:8373352, GO:0070458=PMID:8373352, GO:0042178=PMID:8373352, GO:0006749=PMID:8373352, GO:0044281=Reactome:REACT_111217, GO:0019899=PMID:8373352, GO:0004364=PMID:8373352, GO:0042803=PMID:8373352, GO:0005829=Reactome:REACT_6854} P09488 Glutathione S-transferase Mu 1 protein 20121214 {GO:0043295=IDA, GO:0005737=IDA, GO:0006805=TAS, GO:0018916=IDA, GO:0070458=IDA, GO:0042178=IDA, GO:0006749=IDA, GO:0044281=TAS, GO:0019899=IPI, GO:0004364=IDA, GO:0042803=IPI, GO:0005829=TAS} cellular detoxification of nitrogen compound, glutathione metabolic process, nitrobenzene metabolic process, small molecule metabolic process, xenobiotic catabolic process, xenobiotic metabolic process cytoplasm, cytosol enzyme binding, glutathione binding, glutathione transferase activity, protein homodimerization activity Human GSTM2 BHF-UCL UniProtKB {GO:0070458=PMID:2034681, GO:0042178=PMID:8373352, GO:0005102=PMID:22406107, GO:0071313=PMID:22406107, GO:0006749=PMID:8373352, GO:0010881=PMID:22406107, GO:0004364=PMID:8373352, GO:0014809=PMID:17023043, GO:0042803=PMID:8373352, GO:0060316=PMID:17023043, GO:0005737=PMID:8373352, GO:0043295=PMID:2034681, GO:0016529=PMID:22406107, GO:0018916=PMID:2034681, GO:0010880=PMID:17023043, GO:0060315=PMID:22406107, GO:0055119=PMID:21323602, GO:0019899=PMID:8373352} P28161 Glutathione S-transferase Mu 2 protein 20121214 {GO:0070458=IDA, GO:0042178=IDA, GO:0005102=IPI, GO:0071313=IDA, GO:0006749=IDA, GO:0010881=IC, GO:0004364=IDA, GO:0014809=IC, GO:0042803=IPI, GO:0060316=IDA, GO:0005737=IDA, GO:0043295=IDA, GO:0016529=IDA, GO:0018916=IDA, GO:0010880=IDA, GO:0060315=IDA, GO:0055119=TAS, GO:0019899=IPI} cellular detoxification of nitrogen compound, cellular response to caffeine, glutathione metabolic process, negative regulation of ryanodine-sensitive calcium-release channel activity, nitrobenzene metabolic process, positive regulation of ryanodine-sensitive calcium-release channel activity, regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion, regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum, regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion, relaxation of cardiac muscle, xenobiotic catabolic process cytoplasm, sarcoplasmic reticulum enzyme binding, glutathione binding, glutathione transferase activity, protein homodimerization activity, receptor binding Human GSTM3 BHF-UCL UniProtKB {GO:0005737=PMID:8373352, GO:0043295=PMID:8373352, GO:0043627=PMID:10037815, GO:0018916=PMID:8373352, GO:0008065=PMID:2345169, GO:0070458=PMID:8373352, GO:0042178=PMID:8373352, GO:0006749=PMID:8373352, GO:0019899=PMID:8373352, GO:0004364=PMID:8373352, GO:0042803=PMID:8373352, GO:0042802=PMID:19060904} P21266 Glutathione S-transferase Mu 3 protein 20121214 {GO:0005737=IDA, GO:0043295=IDA, GO:0043627=IEP, GO:0018916=IDA, GO:0008065=TAS, GO:0070458=IDA, GO:0042178=IDA, GO:0006749=IDA, GO:0019899=IPI, GO:0004364=IDA, GO:0042803=IPI, GO:0042802=IPI} cellular detoxification of nitrogen compound, establishment of blood-nerve barrier, glutathione metabolic process, nitrobenzene metabolic process, response to estrogen stimulus, xenobiotic catabolic process cytoplasm enzyme binding, glutathione binding, glutathione transferase activity, identical protein binding, protein homodimerization activity Human GSTM4 InterPro UniProtKB {GO:0005737=PMID:8373352, GO:0043295=PMID:8373352, GO:0006805=Reactome:REACT_13433, GO:0042178=PMID:8373352, GO:0005789=Reactome:REACT_6947, GO:0006749=PMID:8373352, GO:0044281=Reactome:REACT_111217, GO:0019899=PMID:8373352, GO:0004364=GO_REF:0000002, GO:0042803=PMID:8373352} Q4JNT8 Glutathione S-transferase Mu 4 protein 20130413 {GO:0005737=IDA, GO:0043295=IDA, GO:0006805=TAS, GO:0042178=IDA, GO:0005789=TAS, GO:0006749=IDA, GO:0044281=TAS, GO:0019899=IPI, GO:0004364=IEA, GO:0042803=IPI} glutathione metabolic process, small molecule metabolic process, xenobiotic catabolic process, xenobiotic metabolic process cytoplasm, endoplasmic reticulum membrane enzyme binding, glutathione binding, glutathione transferase activity, protein homodimerization activity Human InterPro:IPR003081 GSTM5 InterPro UniProtKB {GO:0006805=Reactome:REACT_13433, GO:0005789=Reactome:REACT_6947, GO:0006749=PMID:10587441, GO:0044281=Reactome:REACT_111217, GO:0004364=GO_REF:0000002} Q5T8R1 Glutathione S-transferase Mu 5 protein 20130413 {GO:0006805=TAS, GO:0005789=TAS, GO:0006749=IDA, GO:0044281=TAS, GO:0004364=IEA} glutathione metabolic process, small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane glutathione transferase activity Human InterPro:IPR003081 GSTO1 InterPro UniProtKB {GO:0006805=Reactome:REACT_13433, GO:0014810=PMID:11035031, GO:0042178=PMID:12928150, GO:0010881=PMID:11035031, GO:0044281=Reactome:REACT_111217, GO:0004364=GO_REF:0000002, GO:0045174=PMID:11511179, GO:0005829=Reactome:REACT_6854, GO:0060316=PMID:11035031, GO:0019852=PMID:11511179, GO:0050610=GO_REF:0000003, GO:0005737=GO_REF:0000002, GO:0010880=PMID:11035031, GO:0060315=PMID:11035031, GO:0016491=PMID:11511179, GO:0071243=PMID:11511179} Q5TA02 Glutathione S-transferase omega-1 protein 20130413 {GO:0006805=TAS, GO:0014810=IC, GO:0042178=IDA, GO:0010881=IC, GO:0044281=TAS, GO:0004364=IEA, GO:0045174=IDA, GO:0005829=TAS, GO:0060316=IDA, GO:0019852=IDA, GO:0050610=IEA, GO:0005737=IEA, GO:0010880=IDA, GO:0060315=IDA, GO:0016491=IDA, GO:0071243=IDA} L-ascorbic acid metabolic process, cellular response to arsenic-containing substance, negative regulation of ryanodine-sensitive calcium-release channel activity, positive regulation of ryanodine-sensitive calcium-release channel activity, positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion, regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion, regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum, small molecule metabolic process, xenobiotic catabolic process, xenobiotic metabolic process cytoplasm, cytosol glutathione dehydrogenase (ascorbate) activity, glutathione transferase activity, methylarsonate reductase activity, oxidoreductase activity Human InterPro:IPR005442 GSTO2 Reactome UniProtKB {GO:0006805=Reactome:REACT_13433, GO:0006767=Reactome:REACT_11238, GO:0044281=Reactome:REACT_111217, GO:0004364=GO_REF:0000003, GO:0045174=PMID:15970797, GO:0005829=Reactome:REACT_11095, GO:0019852=Reactome:REACT_11202, GO:0050610=GO_REF:0000003, GO:0005737=GO_REF:0000002, GO:0006766=Reactome:REACT_11193, GO:0016491=PMID:15970797, GO:0071243=PMID:15970797, GO:0016740=GO_REF:0000038, GO:0055114=PMID:15970797} Q9H4Y5 Glutathione S-transferase omega-2 protein 20070705 {GO:0006805=TAS, GO:0006767=TAS, GO:0044281=TAS, GO:0004364=IEA, GO:0045174=IDA, GO:0005829=TAS, GO:0019852=TAS, GO:0050610=IEA, GO:0005737=IEA, GO:0006766=TAS, GO:0016491=IDA, GO:0071243=IDA, GO:0016740=IEA, GO:0055114=IDA} L-ascorbic acid metabolic process, cellular response to arsenic-containing substance, oxidation-reduction process, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process, xenobiotic metabolic process cytoplasm, cytosol glutathione dehydrogenase (ascorbate) activity, glutathione transferase activity, methylarsonate reductase activity, oxidoreductase activity, transferase activity Human GSTP1 BHF-UCL UniProtKB {GO:0005515=PMID:16636664, GO:0006805=Reactome:REACT_13433, GO:0032691=PMID:18962899, GO:0048147=GO_REF:0000024, GO:0006749=PMID:1540159, GO:0005634=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0032872=GO_REF:0000024, GO:0019207=GO_REF:0000024, GO:0071638=PMID:18962899, GO:0032873=GO_REF:0000024, GO:0005829=Reactome:REACT_6854, GO:0043409=PMID:18962899, GO:0005739=GO_REF:0000039, GO:0005622=PMID:18962899, GO:0005737=PMID:16130169, GO:0043407=PMID:11408560, GO:0060547=GO_REF:0000024, GO:0070373=PMID:11408560, GO:0035726=GO_REF:0000024, GO:0043508=PMID:16636664, GO:0008432=GO_REF:0000024, GO:0070372=GO_REF:0000024, GO:0070026=PMID:11533048, GO:0032930=GO_REF:0000024, GO:0043124=GO_REF:0000024, GO:0043066=PMID:16636664, GO:0032720=PMID:18962899, GO:0004364=PMID:1540159, GO:0002674=PMID:18962899, GO:0007417=PMID:9802272, GO:0010804=PMID:16636664, GO:0097057=PMID:16636664, GO:0009890=PMID:18962899, GO:0071222=GO_REF:0000024, GO:0070664=GO_REF:0000024, GO:0006469=PMID:16636664, GO:0035732=PMID:12871931, GO:0000302=GO_REF:0000024, GO:0051771=PMID:18962899, GO:0035730=PMID:11533048, GO:0035731=PMID:11533048} P09211 Glutathione S-transferase P protein 20110309 {GO:0005515=IPI, GO:0006805=TAS, GO:0032691=IDA, GO:0048147=ISS, GO:0006749=IDA, GO:0005634=IEA, GO:0044281=TAS, GO:0032872=ISS, GO:0019207=ISS, GO:0071638=IDA, GO:0032873=ISS, GO:0005829=TAS, GO:0043409=NAS, GO:0005739=IEA, GO:0005622=IDA, GO:0005737=TAS, GO:0043407=IDA, GO:0060547=ISS, GO:0070373=IDA, GO:0035726=ISS, GO:0043508=IDA, GO:0008432=ISS, GO:0070372=ISS, GO:0070026=NAS, GO:0032930=ISS, GO:0043124=ISS, GO:0043066=IDA, GO:0032720=IDA, GO:0004364=IDA, GO:0002674=NAS, GO:0007417=TAS, GO:0010804=IC, GO:0097057=IDA, GO:0009890=IDA, GO:0071222=ISS, GO:0070664=ISS, GO:0006469=IDA, GO:0035732=NAS, GO:0000302=ISS, GO:0051771=IDA, GO:0035730=IDA, GO:0035731=IDA} cellular response to lipopolysaccharide, central nervous system development, common myeloid progenitor cell proliferation, glutathione metabolic process, negative regulation of ERK1 and ERK2 cascade, negative regulation of I-kappaB kinase/NF-kappaB cascade, negative regulation of JUN kinase activity, negative regulation of MAP kinase activity, negative regulation of MAPK cascade, negative regulation of acute inflammatory response, negative regulation of apoptotic process, negative regulation of biosynthetic process, negative regulation of fibroblast proliferation, negative regulation of interleukin-1 beta production, negative regulation of leukocyte proliferation, negative regulation of monocyte chemotactic protein-1 production, negative regulation of necrotic cell death, negative regulation of nitric-oxide synthase biosynthetic process, negative regulation of protein kinase activity, negative regulation of stress-activated MAPK cascade, negative regulation of tumor necrosis factor production, negative regulation of tumor necrosis factor-mediated signaling pathway, nitric oxide storage, positive regulation of superoxide anion generation, regulation of ERK1 and ERK2 cascade, regulation of stress-activated MAPK cascade, response to reactive oxygen species, small molecule metabolic process, xenobiotic metabolic process TRAF2-GSTP1 complex, cytoplasm, cytosol, intracellular, mitochondrion, nucleus JUN kinase binding, S-nitrosoglutathione binding, dinitrosyl-iron complex binding, glutathione transferase activity, kinase regulator activity, nitric oxide binding, protein binding Human UniProtKB:P19157 GSTT1 ENSEMBL UniProtKB {GO:0004602=GO_REF:0000019, GO:0014070=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0006749=GO_REF:0000019, GO:0004364=GO_REF:0000019, GO:0016740=GO_REF:0000038, GO:0005829=GO_REF:0000019} Q6IC69 GSTT1 protein protein 20130413 {GO:0004602=IEA, GO:0014070=IEA, GO:0042493=IEA, GO:0006749=IEA, GO:0004364=IEA, GO:0016740=IEA, GO:0005829=IEA} glutathione metabolic process, response to drug, response to organic cyclic compound cytosol glutathione peroxidase activity, glutathione transferase activity, transferase activity Human Ensembl:ENSRNOP00000001669 GSTT2 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0004364=GO_REF:0000003} P0CG29 Glutathione S-transferase theta-2 protein 20101115 {GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0004364=IEA} cytoplasm, nucleolus, nucleus glutathione transferase activity Human GSTZ1 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0006559=Reactome:REACT_1786, GO:0009072=GO_REF:0000002, GO:0006749=PMID:10739172, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0004364=PMID:10739172, GO:0042803=PMID:10739172, GO:0005829=Reactome:REACT_1466, GO:0005739=GO_REF:0000024, GO:0004602=PMID:9396740, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000002, GO:0006572=GO_REF:0000037, GO:0016034=Reactome:REACT_1466, GO:0016853=GO_REF:0000038, GO:0016740=GO_REF:0000038} O43708 Maleylacetoacetate isomerase protein 20130415 {GO:0005515=IPI, GO:0006559=TAS, GO:0009072=IEA, GO:0006749=IDA, GO:0044281=TAS, GO:0003824=IEA, GO:0004364=IDA, GO:0042803=IPI, GO:0005829=TAS, GO:0005739=ISS, GO:0004602=TAS, GO:0034641=TAS, GO:0005737=IEA, GO:0006572=IEA, GO:0016034=EXP, GO:0016853=IEA, GO:0016740=IEA} L-phenylalanine catabolic process, aromatic amino acid family metabolic process, cellular nitrogen compound metabolic process, glutathione metabolic process, small molecule metabolic process, tyrosine catabolic process cytoplasm, cytosol, mitochondrion catalytic activity, glutathione peroxidase activity, glutathione transferase activity, isomerase activity, maleylacetoacetate isomerase activity, protein binding, protein homodimerization activity, transferase activity Human UniProtKB:P16333 GSX2 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0002087=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0021798=GO_REF:0000019, GO:0021889=GO_REF:0000019, GO:0048665=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0048853=GO_REF:0000019, GO:0021575=GO_REF:0000019, GO:0021527=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0060163=GO_REF:0000019} Q9BZM3 GS homeobox 2 protein 20130413 {GO:0043565=IEA, GO:0002087=IEA, GO:0003700=IEA, GO:0021798=IEA, GO:0021889=IEA, GO:0048665=IEA, GO:0005634=IEA, GO:0048853=IEA, GO:0021575=IEA, GO:0021527=IEA, GO:0006351=IEA, GO:0060163=IEA} forebrain dorsal/ventral pattern formation, forebrain morphogenesis, hindbrain morphogenesis, neuron fate specification, olfactory bulb interneuron differentiation, regulation of respiratory gaseous exchange by neurological system process, spinal cord association neuron differentiation, subpallium neuron fate commitment, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0191 GTDC1 UniProtKB UniProtKB {GO:0009058=GO_REF:0000002, GO:0016757=GO_REF:0000037, GO:0016740=GO_REF:0000038} Q4AE62 Glycosyltransferase-like domain-containing protein 1 protein 20130413 {GO:0009058=IEA, GO:0016757=IEA, GO:0016740=IEA} biosynthetic process transferase activity, transferase activity, transferring glycosyl groups Human UniProtKB-KW:KW-0328 GTF2A1 BHF-UCL UniProtKB {GO:0005515=PMID:8006019, GO:0010467=Reactome:REACT_71, GO:0022415=Reactome:REACT_6361, GO:0006355=GO_REF:0000037, GO:0006368=Reactome:REACT_2089, GO:0006367=Reactome:REACT_1851, GO:0046982=PMID:8626665, GO:0006366=PMID:7724559, GO:0003713=PMID:8224850, GO:0003677=PMID:7724559, GO:0016032=Reactome:REACT_6256, GO:0017025=PMID:7724559, GO:0005672=PMID:7724559, GO:0005654=Reactome:REACT_1844, GO:0008134=PMID:8626665} P52655 Transcription initiation factor IIA subunit 1 protein 20081029 {GO:0005515=IPI, GO:0010467=TAS, GO:0022415=TAS, GO:0006355=IEA, GO:0006368=TAS, GO:0006367=TAS, GO:0046982=IPI, GO:0006366=IDA, GO:0003713=TAS, GO:0003677=IDA, GO:0016032=TAS, GO:0017025=IPI, GO:0005672=IDA, GO:0005654=TAS, GO:0008134=IPI} gene expression, regulation of transcription, DNA-dependent, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, viral reproduction, viral reproductive process nucleoplasm, transcription factor TFIIA complex DNA binding, TBP-class protein binding, protein binding, protein heterodimerization activity, transcription coactivator activity, transcription factor binding Human UniProtKB:P52657 GTF2A1L PINC UniProtKB {GO:0006355=GO_REF:0000037, GO:0006367=GO_REF:0000002, GO:0006366=PMID:10364255, GO:0003713=PMID:10364255, GO:0005672=GO_REF:0000002, GO:0003677=GO_REF:0000037} Q9UNN4 TFIIA-alpha and beta-like factor protein 20030904 {GO:0006355=IEA, GO:0006367=IEA, GO:0006366=TAS, GO:0003713=TAS, GO:0005672=IEA, GO:0003677=IEA} regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter transcription factor TFIIA complex DNA binding, transcription coactivator activity Human GTF2A2 BHF-UCL UniProtKB {GO:0001103=GO_REF:0000019, GO:0005515=PMID:8626665, GO:0010467=Reactome:REACT_71, GO:0022415=Reactome:REACT_6361, GO:0006368=Reactome:REACT_2089, GO:0006367=Reactome:REACT_1851, GO:0046982=PMID:8626665, GO:0006366=PMID:8626665, GO:0003713=PMID:7958899, GO:0042803=PMID:8626665, GO:0051091=PMID:8626665, GO:0045944=PMID:7958899, GO:0019048=GO_REF:0000037, GO:0017025=PMID:8626665, GO:0016032=Reactome:REACT_6256, GO:0005672=PMID:7724559, GO:0005654=Reactome:REACT_1844, GO:0051123=PMID:7958899, GO:0008134=PMID:8626665} P52657 Transcription initiation factor IIA subunit 2 protein 20081029 {GO:0001103=IEA, GO:0005515=IPI, GO:0010467=TAS, GO:0022415=TAS, GO:0006368=TAS, GO:0006367=TAS, GO:0046982=IPI, GO:0006366=IDA, GO:0003713=IDA, GO:0042803=IPI, GO:0051091=IDA, GO:0045944=IDA, GO:0019048=IEA, GO:0017025=IPI, GO:0016032=TAS, GO:0005672=IDA, GO:0005654=TAS, GO:0051123=IDA, GO:0008134=IPI} RNA polymerase II transcriptional preinitiation complex assembly, gene expression, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, viral reproduction, viral reproductive process, virus-host interaction nucleoplasm, transcription factor TFIIA complex RNA polymerase II repressing transcription factor binding, TBP-class protein binding, protein binding, protein heterodimerization activity, protein homodimerization activity, transcription coactivator activity, transcription factor binding Human GTF2B IntAct UniProtKB {GO:0005515=PMID:12529369, GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006352=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0006368=Reactome:REACT_2089, GO:0006367=Reactome:REACT_1851, GO:0006366=Reactome:REACT_1366, GO:0003677=GO_REF:0000019, GO:0046966=PMID:8524305, GO:0019048=GO_REF:0000037, GO:0016032=Reactome:REACT_6256, GO:0017025=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_1844, GO:0008134=PMID:9722567} Q00403 Transcription initiation factor IIB protein 20130415 {GO:0005515=IPI, GO:0022415=TAS, GO:0010467=TAS, GO:0006352=IEA, GO:0006355=IEA, GO:0006368=TAS, GO:0006367=TAS, GO:0006366=TAS, GO:0003677=IEA, GO:0046966=IPI, GO:0019048=IEA, GO:0016032=TAS, GO:0017025=IEA, GO:0008270=IEA, GO:0005654=TAS, GO:0008134=IPI} DNA-dependent transcription, initiation, gene expression, regulation of transcription, DNA-dependent, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, viral reproduction, viral reproductive process, virus-host interaction nucleoplasm DNA binding, TBP-class protein binding, protein binding, thyroid hormone receptor binding, transcription factor binding, zinc ion binding Human UniProtKB:P48281 GTF2E1 Reactome UniProtKB {GO:0005515=PMID:7667268, GO:0043565=GO_REF:0000002, GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006368=Reactome:REACT_2089, GO:0006355=GO_REF:0000037, GO:0006367=Reactome:REACT_1851, GO:0006366=Reactome:REACT_1366, GO:0019048=GO_REF:0000037, GO:0016032=Reactome:REACT_6256, GO:0005654=Reactome:REACT_1844, GO:0008270=GO_REF:0000002} P29083 General transcription factor IIE subunit 1 protein 20130213 {GO:0005515=IPI, GO:0043565=IEA, GO:0022415=TAS, GO:0010467=TAS, GO:0006368=TAS, GO:0006355=IEA, GO:0006367=TAS, GO:0006366=TAS, GO:0019048=IEA, GO:0016032=TAS, GO:0005654=TAS, GO:0008270=IEA} gene expression, regulation of transcription, DNA-dependent, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, viral reproduction, viral reproductive process, virus-host interaction nucleoplasm protein binding, sequence-specific DNA binding, zinc ion binding Human GTF2E2 HPA UniProtKB {GO:0005515=PMID:21988832, GO:0010467=Reactome:REACT_71, GO:0022415=Reactome:REACT_6361, GO:0006355=GO_REF:0000037, GO:0006368=Reactome:REACT_2089, GO:0006367=Reactome:REACT_1851, GO:0006366=Reactome:REACT_1366, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0016032=Reactome:REACT_6256, GO:0005654=Reactome:REACT_1844, GO:0005673=GO_REF:0000002} P29084 Transcription initiation factor IIE subunit beta protein 20110516 {GO:0005515=IPI, GO:0010467=TAS, GO:0022415=TAS, GO:0006355=IEA, GO:0006368=TAS, GO:0006367=TAS, GO:0006366=TAS, GO:0005634=IDA, GO:0003677=IEA, GO:0005737=IDA, GO:0016032=TAS, GO:0005654=TAS, GO:0005673=IEA} gene expression, regulation of transcription, DNA-dependent, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, viral reproduction, viral reproductive process cytoplasm, nucleoplasm, nucleus, transcription factor TFIIE complex DNA binding, protein binding Human GTF2F1 HPA UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:12737519, GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006368=Reactome:REACT_2089, GO:0030054=GO_REF:0000052, GO:0006367=Reactome:REACT_1851, GO:0006366=Reactome:REACT_1366, GO:0003713=PMID:7854423, GO:0006370=Reactome:REACT_1470, GO:0005634=GO_REF:0000052, GO:0019211=PMID:12721286, GO:0003824=GO_REF:0000002, GO:0009615=PMID:16548883, GO:0003677=GO_REF:0000037, GO:0050434=Reactome:REACT_6162, GO:0000398=Reactome:REACT_1753, GO:0045944=GO_REF:0000019, GO:0016032=Reactome:REACT_6256, GO:0005654=Reactome:REACT_6355, GO:0045893=GO_REF:0000002, GO:0005674=PMID:1734283, GO:0008134=PMID:8625415} P35269 General transcription factor IIF subunit 1 protein 20101115 {GO:0008380=TAS, GO:0005515=IPI, GO:0022415=TAS, GO:0010467=TAS, GO:0006368=TAS, GO:0030054=IDA, GO:0006367=TAS, GO:0006366=TAS, GO:0003713=TAS, GO:0006370=TAS, GO:0005634=IDA, GO:0019211=IDA, GO:0003824=IEA, GO:0009615=IEP, GO:0003677=IEA, GO:0050434=TAS, GO:0000398=TAS, GO:0045944=IEA, GO:0016032=TAS, GO:0005654=TAS, GO:0045893=IEA, GO:0005674=TAS, GO:0008134=IPI} 7-methylguanosine mRNA capping, RNA splicing, gene expression, mRNA splicing, via spliceosome, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of viral transcription, response to virus, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, viral reproduction, viral reproductive process cell junction, nucleoplasm, nucleus, transcription factor TFIIF complex DNA binding, catalytic activity, phosphatase activator activity, protein binding, transcription coactivator activity, transcription factor binding Human GTF2F2 HPA UniProtKB {GO:0008026=GO_REF:0000002, GO:0005515=PMID:20195357, GO:0008380=Reactome:REACT_1735, GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000037, GO:0006368=Reactome:REACT_2089, GO:0006367=Reactome:REACT_1851, GO:0006366=Reactome:REACT_1366, GO:0006370=Reactome:REACT_1470, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0050434=Reactome:REACT_6162, GO:0000398=Reactome:REACT_1753, GO:0015630=GO_REF:0000052, GO:0016032=Reactome:REACT_6256, GO:0005654=Reactome:REACT_6355, GO:0005674=GO_REF:0000002} P13984 General transcription factor IIF subunit 2 protein 20101115 {GO:0008026=IEA, GO:0005515=IPI, GO:0008380=TAS, GO:0022415=TAS, GO:0010467=TAS, GO:0006355=IEA, GO:0006368=TAS, GO:0006367=TAS, GO:0006366=TAS, GO:0006370=TAS, GO:0005634=IDA, GO:0003677=IEA, GO:0005524=IEA, GO:0050434=TAS, GO:0000398=TAS, GO:0015630=IDA, GO:0016032=TAS, GO:0005654=TAS, GO:0005674=IEA} 7-methylguanosine mRNA capping, RNA splicing, gene expression, mRNA splicing, via spliceosome, positive regulation of viral transcription, regulation of transcription, DNA-dependent, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, viral reproduction, viral reproductive process microtubule cytoskeleton, nucleoplasm, nucleus, transcription factor TFIIF complex ATP binding, ATP-dependent helicase activity, DNA binding, protein binding Human GTF2H1 GOC UniProtKB {GO:0005515=PMID:10734143, GO:0010467=Reactome:REACT_71, GO:0022415=Reactome:REACT_6361, GO:0006368=Reactome:REACT_2089, GO:0006367=Reactome:REACT_1851, GO:0006366=Reactome:REACT_1366, GO:0006363=Reactome:REACT_1074, GO:0006362=Reactome:REACT_2204, GO:0006361=Reactome:REACT_1974, GO:0006360=Reactome:REACT_1309, GO:0000079=PMID:7533895, GO:0000439=GO_REF:0000002, GO:0045944=PMID:8692841, GO:0016032=Reactome:REACT_6256, GO:0008094=PMID:9852112, GO:0006370=Reactome:REACT_1470, GO:0008353=PMID:9852112, GO:0006351=GO_REF:0000002, GO:0050434=Reactome:REACT_6162, GO:0006281=Reactome:REACT_216, GO:0004672=PMID:9852112, GO:0006283=Reactome:REACT_1628, GO:0006468=PMID:9852112, GO:0005654=Reactome:REACT_2233, GO:0006289=Reactome:REACT_1826, GO:0000718=Reactome:REACT_311, GO:0005675=PMID:9852112} P32780 General transcription factor IIH subunit 1 protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0022415=TAS, GO:0006368=TAS, GO:0006367=TAS, GO:0006366=TAS, GO:0006363=TAS, GO:0006362=TAS, GO:0006361=TAS, GO:0006360=TAS, GO:0000079=TAS, GO:0000439=IEA, GO:0045944=IDA, GO:0016032=TAS, GO:0008094=IDA, GO:0006370=TAS, GO:0008353=IDA, GO:0006351=IEA, GO:0050434=TAS, GO:0006281=TAS, GO:0004672=IDA, GO:0006283=TAS, GO:0006468=IDA, GO:0005654=TAS, GO:0006289=TAS, GO:0000718=TAS, GO:0005675=IDA} 7-methylguanosine mRNA capping, DNA repair, gene expression, nucleotide-excision repair, nucleotide-excision repair, DNA damage removal, positive regulation of transcription from RNA polymerase II promoter, positive regulation of viral transcription, protein phosphorylation, regulation of cyclin-dependent protein serine/threonine kinase activity, termination of RNA polymerase I transcription, transcription elongation from RNA polymerase I promoter, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase I promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase I promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transcription-coupled nucleotide-excision repair, viral reproduction, viral reproductive process core TFIIH complex, holo TFIIH complex, nucleoplasm DNA-dependent ATPase activity, RNA polymerase II carboxy-terminal domain kinase activity, protein binding, protein kinase activity Human GTF2H2 GOC UniProtKB {GO:0005515=PMID:8692842, GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006368=Reactome:REACT_2089, GO:0003700=PMID:8194529, GO:0006367=Reactome:REACT_1851, GO:0006366=Reactome:REACT_1366, GO:0006363=Reactome:REACT_1074, GO:0006362=Reactome:REACT_2204, GO:0006361=Reactome:REACT_1974, GO:0006360=Reactome:REACT_1309, GO:0006412=PMID:8194529, GO:0000439=GO_REF:0000002, GO:0016032=Reactome:REACT_6256, GO:0009411=PMID:8194529, GO:0008094=PMID:9852112, GO:0006370=Reactome:REACT_1470, GO:0003676=PMID:8194529, GO:0008353=PMID:9852112, GO:0002031=PMID:15775968, GO:0006351=GO_REF:0000002, GO:0050434=Reactome:REACT_6162, GO:0006281=Reactome:REACT_216, GO:0004672=PMID:9852112, GO:0047485=PMID:8652557, GO:0006283=Reactome:REACT_1628, GO:0006468=PMID:9852112, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_2233, GO:0006289=Reactome:REACT_1826, GO:0000718=Reactome:REACT_311, GO:0005675=PMID:9852112, GO:0008135=PMID:8194529} Q13888 General transcription factor IIH subunit 2 protein 20130413 {GO:0005515=IPI, GO:0022415=TAS, GO:0010467=TAS, GO:0006368=TAS, GO:0003700=NAS, GO:0006367=TAS, GO:0006366=TAS, GO:0006363=TAS, GO:0006362=TAS, GO:0006361=TAS, GO:0006360=TAS, GO:0006412=TAS, GO:0000439=IEA, GO:0016032=TAS, GO:0009411=TAS, GO:0008094=IDA, GO:0006370=TAS, GO:0003676=TAS, GO:0008353=IDA, GO:0002031=IMP, GO:0006351=IEA, GO:0050434=TAS, GO:0006281=TAS, GO:0004672=IDA, GO:0047485=IPI, GO:0006283=TAS, GO:0006468=IDA, GO:0008270=IEA, GO:0005654=TAS, GO:0006289=TAS, GO:0000718=TAS, GO:0005675=IDA, GO:0008135=TAS} 7-methylguanosine mRNA capping, DNA repair, G-protein coupled receptor internalization, gene expression, nucleotide-excision repair, nucleotide-excision repair, DNA damage removal, positive regulation of viral transcription, protein phosphorylation, response to UV, termination of RNA polymerase I transcription, transcription elongation from RNA polymerase I promoter, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase I promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase I promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transcription-coupled nucleotide-excision repair, translation, viral reproduction, viral reproductive process core TFIIH complex, holo TFIIH complex, nucleoplasm DNA-dependent ATPase activity, RNA polymerase II carboxy-terminal domain kinase activity, nucleic acid binding, protein N-terminus binding, protein binding, protein kinase activity, sequence-specific DNA binding transcription factor activity, translation factor activity, nucleic acid binding, zinc ion binding Human GTF2H2D null null {} null null null null {} null null null GTF2H3 GOC UniProtKB {GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006368=Reactome:REACT_2089, GO:0003700=GO_REF:0000029, GO:0006367=Reactome:REACT_1851, GO:0006366=Reactome:REACT_1366, GO:0006363=Reactome:REACT_1074, GO:0006362=Reactome:REACT_2204, GO:0006361=Reactome:REACT_1974, GO:0006360=Reactome:REACT_1309, GO:0006412=PMID:8194529, GO:0046872=GO_REF:0000037, GO:0000439=GO_REF:0000002, GO:0016032=Reactome:REACT_6256, GO:0008094=PMID:9852112, GO:0006355=GO_REF:0000029, GO:0006370=Reactome:REACT_1470, GO:0008353=PMID:9852112, GO:0050434=Reactome:REACT_6162, GO:0003684=GO_REF:0000029, GO:0004672=PMID:9852112, GO:0047485=PMID:8652557, GO:0006281=Reactome:REACT_216, GO:0006283=Reactome:REACT_1628, GO:0006468=PMID:9852112, GO:0005654=Reactome:REACT_2233, GO:0006289=Reactome:REACT_1826, GO:0000718=Reactome:REACT_311, GO:0005675=PMID:9852112, GO:0008135=PMID:8194529} Q13889 General transcription factor IIH subunit 3 protein 20130413 {GO:0022415=TAS, GO:0010467=TAS, GO:0006368=TAS, GO:0003700=NAS, GO:0006367=TAS, GO:0006366=TAS, GO:0006363=TAS, GO:0006362=TAS, GO:0006361=TAS, GO:0006360=TAS, GO:0006412=TAS, GO:0046872=IEA, GO:0000439=IEA, GO:0016032=TAS, GO:0008094=IDA, GO:0006355=NAS, GO:0006370=TAS, GO:0008353=IDA, GO:0050434=TAS, GO:0003684=NAS, GO:0004672=IDA, GO:0047485=IPI, GO:0006281=TAS, GO:0006283=TAS, GO:0006468=IDA, GO:0005654=TAS, GO:0006289=TAS, GO:0000718=TAS, GO:0005675=IDA, GO:0008135=TAS} 7-methylguanosine mRNA capping, DNA repair, gene expression, nucleotide-excision repair, nucleotide-excision repair, DNA damage removal, positive regulation of viral transcription, protein phosphorylation, regulation of transcription, DNA-dependent, termination of RNA polymerase I transcription, transcription elongation from RNA polymerase I promoter, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase I promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase I promoter, transcription initiation from RNA polymerase II promoter, transcription-coupled nucleotide-excision repair, translation, viral reproduction, viral reproductive process core TFIIH complex, holo TFIIH complex, nucleoplasm DNA-dependent ATPase activity, RNA polymerase II carboxy-terminal domain kinase activity, damaged DNA binding, metal ion binding, protein N-terminus binding, protein kinase activity, sequence-specific DNA binding transcription factor activity, translation factor activity, nucleic acid binding Human GTF2H4 GOC UniProtKB {GO:0005515=PMID:17466626, GO:0010467=Reactome:REACT_71, GO:0022415=Reactome:REACT_6361, GO:0006368=Reactome:REACT_2089, GO:0003700=PMID:9118947, GO:0006367=Reactome:REACT_1851, GO:0006366=Reactome:REACT_1366, GO:0006363=Reactome:REACT_1074, GO:0006362=Reactome:REACT_2204, GO:0006361=Reactome:REACT_1974, GO:0006360=Reactome:REACT_1309, GO:0000439=GO_REF:0000002, GO:0004003=GO_REF:0000002, GO:0016032=Reactome:REACT_6256, GO:0008094=PMID:9852112, GO:0006370=Reactome:REACT_1470, GO:0008353=PMID:9852112, GO:0050434=Reactome:REACT_6162, GO:0004672=PMID:9852112, GO:0006281=Reactome:REACT_216, GO:0006283=Reactome:REACT_1628, GO:0006468=PMID:9852112, GO:0005654=Reactome:REACT_2233, GO:0006289=Reactome:REACT_1826, GO:0000718=Reactome:REACT_311, GO:0005675=PMID:9852112} Q92759 General transcription factor IIH subunit 4 protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0022415=TAS, GO:0006368=TAS, GO:0003700=TAS, GO:0006367=TAS, GO:0006366=TAS, GO:0006363=TAS, GO:0006362=TAS, GO:0006361=TAS, GO:0006360=TAS, GO:0000439=IEA, GO:0004003=IEA, GO:0016032=TAS, GO:0008094=IDA, GO:0006370=TAS, GO:0008353=IDA, GO:0050434=TAS, GO:0004672=IDA, GO:0006281=TAS, GO:0006283=TAS, GO:0006468=IDA, GO:0005654=TAS, GO:0006289=TAS, GO:0000718=TAS, GO:0005675=IDA} 7-methylguanosine mRNA capping, DNA repair, gene expression, nucleotide-excision repair, nucleotide-excision repair, DNA damage removal, positive regulation of viral transcription, protein phosphorylation, termination of RNA polymerase I transcription, transcription elongation from RNA polymerase I promoter, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase I promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase I promoter, transcription initiation from RNA polymerase II promoter, transcription-coupled nucleotide-excision repair, viral reproduction, viral reproductive process core TFIIH complex, holo TFIIH complex, nucleoplasm ATP-dependent DNA helicase activity, DNA-dependent ATPase activity, RNA polymerase II carboxy-terminal domain kinase activity, protein binding, protein kinase activity, sequence-specific DNA binding transcription factor activity Human GTF2H5 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0000439=GO_REF:0000002, GO:0006289=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q6ZYL4 General transcription factor IIH subunit 5 protein 20130413 {GO:0006355=IEA, GO:0000439=IEA, GO:0006289=IEA, GO:0006351=IEA} nucleotide-excision repair, regulation of transcription, DNA-dependent, transcription, DNA-dependent core TFIIH complex Human UniProtKB-KW:KW-0805 GTF2I HPA UniProtKB {GO:0005515=PMID:9012831, GO:0006367=PMID:9334314, GO:0003700=PMID:9334314, GO:0006366=PMID:9334314, GO:0051481=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0009790=GO_REF:0000019, GO:0042995=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0007165=PMID:9012831, GO:0005737=GO_REF:0000039, GO:0016525=PMID:19242469, GO:0043025=GO_REF:0000019, GO:0051019=GO_REF:0000019} P78347 General transcription factor II-I protein 20100326 {GO:0005515=IPI, GO:0006367=TAS, GO:0003700=NAS, GO:0006366=TAS, GO:0051481=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0009790=IEA, GO:0042995=IEA, GO:0003677=IEA, GO:0007165=TAS, GO:0005737=IEA, GO:0016525=IDA, GO:0043025=IEA, GO:0051019=IEA} embryo development, negative regulation of angiogenesis, reduction of cytosolic calcium ion concentration, signal transduction, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter cell projection, cytoplasm, neuronal cell body, nucleolus, nucleus DNA binding, mitogen-activated protein kinase binding, protein binding, sequence-specific DNA binding transcription factor activity NOT Human GTF2IRD1 HPA UniProtKB {GO:0006355=PMID:10575229, GO:0005737=GO_REF:0000052, GO:0003700=PMID:10575229, GO:0003705=PMID:9774679, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0009790=GO_REF:0000019, GO:0003677=GO_REF:0000037} Q9UHL9 General transcription factor II-I repeat domain-containing protein 1 protein 20111111 {GO:0006355=NAS, GO:0005737=IDA, GO:0003700=NAS, GO:0003705=NAS, GO:0005730=IDA, GO:0005634=IDA, GO:0009790=IEA, GO:0003677=IEA} embryo development, regulation of transcription, DNA-dependent cytoplasm, nucleolus, nucleus DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, sequence-specific DNA binding transcription factor activity Human GTF2IRD2 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q86UP8 General transcription factor II-I repeat domain-containing protein 2A protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding Human UniProtKB-SubCell:SL-0191 GTF2IRD2B UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6EKJ0 General transcription factor II-I repeat domain-containing protein 2B protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding Human UniProtKB-SubCell:SL-0191 GTF3A HPA UniProtKB {GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000037, GO:0009303=PMID:8063702, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0005654=Reactome:REACT_1545, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0006383=Reactome:REACT_1371, GO:0003677=GO_REF:0000019} Q92664 Transcription factor IIIA protein 20090616 {GO:0010467=TAS, GO:0006355=IEA, GO:0009303=TAS, GO:0003723=IEA, GO:0005634=IDA, GO:0005654=TAS, GO:0008270=IEA, GO:0003676=IEA, GO:0006383=TAS, GO:0003677=IEA} gene expression, rRNA transcription, regulation of transcription, DNA-dependent, transcription from RNA polymerase III promoter nucleoplasm, nucleus DNA binding, RNA binding, nucleic acid binding, zinc ion binding Human GTF3C1 HPA UniProtKB {GO:0005515=PMID:19299493, GO:0009304=PMID:8164661, GO:0010467=Reactome:REACT_71, GO:0009303=PMID:8164661, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0042791=PMID:17409385, GO:0003677=PMID:17409385, GO:0006383=Reactome:REACT_1371, GO:0006351=PMID:17409385, GO:0042797=PMID:17409385, GO:0000127=PMID:17409385, GO:0030529=GO_REF:0000019, GO:0005654=Reactome:REACT_1779} Q12789 General transcription factor 3C polypeptide 1 protein 20120912 {GO:0005515=IPI, GO:0009304=TAS, GO:0010467=TAS, GO:0009303=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0042791=IC, GO:0003677=IC, GO:0006383=TAS, GO:0006351=IC, GO:0042797=IC, GO:0000127=IDA, GO:0030529=IEA, GO:0005654=TAS} 5S class rRNA transcription from RNA polymerase III type 1 promoter, gene expression, rRNA transcription, tRNA transcription, tRNA transcription from RNA polymerase III promoter, transcription from RNA polymerase III promoter, transcription, DNA-dependent nucleolus, nucleoplasm, nucleus, ribonucleoprotein complex, transcription factor TFIIIC complex DNA binding, protein binding Human GTF3C2 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0042797=PMID:17409385, GO:0000127=PMID:17409385, GO:0005654=Reactome:REACT_1779, GO:0042791=PMID:17409385, GO:0006383=Reactome:REACT_1371, GO:0003677=PMID:17409385, GO:0006351=PMID:17409385} Q8WUA4 General transcription factor 3C polypeptide 2 protein 20130213 {GO:0010467=TAS, GO:0042797=IC, GO:0000127=IDA, GO:0005654=TAS, GO:0042791=IC, GO:0006383=TAS, GO:0003677=IDA, GO:0006351=IDA} 5S class rRNA transcription from RNA polymerase III type 1 promoter, gene expression, tRNA transcription from RNA polymerase III promoter, transcription from RNA polymerase III promoter, transcription, DNA-dependent nucleoplasm, transcription factor TFIIIC complex DNA binding Human GTF3C3 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0042797=PMID:17409385, GO:0000127=PMID:17409385, GO:0005654=Reactome:REACT_1779, GO:0042791=PMID:17409385, GO:0006383=Reactome:REACT_1371, GO:0003677=PMID:17409385, GO:0006351=PMID:17409385} Q9Y5Q9 General transcription factor 3C polypeptide 3 protein 20130213 {GO:0010467=TAS, GO:0042797=IC, GO:0000127=IDA, GO:0005654=TAS, GO:0042791=IC, GO:0006383=TAS, GO:0003677=IC, GO:0006351=IC} 5S class rRNA transcription from RNA polymerase III type 1 promoter, gene expression, tRNA transcription from RNA polymerase III promoter, transcription from RNA polymerase III promoter, transcription, DNA-dependent nucleoplasm, transcription factor TFIIIC complex DNA binding Human GTF3C4 GOC UniProtKB {GO:0005515=PMID:17409385, GO:0010467=Reactome:REACT_71, GO:0016573=PMID:10523658, GO:0043085=PMID:10523658, GO:0042791=PMID:17409385, GO:0006384=PMID:10523658, GO:0003677=PMID:17409385, GO:0006383=Reactome:REACT_1371, GO:0006351=PMID:17409385, GO:0042797=PMID:17409385, GO:0000127=PMID:17409385, GO:0005654=Reactome:REACT_1779, GO:0008047=PMID:10523658, GO:0004402=GO_REF:0000003} Q9UKN8 General transcription factor 3C polypeptide 4 protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0016573=TAS, GO:0043085=TAS, GO:0042791=IC, GO:0006384=TAS, GO:0003677=IC, GO:0006383=TAS, GO:0006351=IC, GO:0042797=IC, GO:0000127=IDA, GO:0005654=TAS, GO:0008047=TAS, GO:0004402=IEA} 5S class rRNA transcription from RNA polymerase III type 1 promoter, gene expression, histone acetylation, positive regulation of catalytic activity, tRNA transcription from RNA polymerase III promoter, transcription from RNA polymerase III promoter, transcription initiation from RNA polymerase III promoter, transcription, DNA-dependent nucleoplasm, transcription factor TFIIIC complex DNA binding, enzyme activator activity, histone acetyltransferase activity, protein binding Human GTF3C5 Reactome UniProtKB {GO:0005515=PMID:17409385, GO:0010467=Reactome:REACT_71, GO:0042797=PMID:17409385, GO:0000127=PMID:17409385, GO:0005654=Reactome:REACT_1779, GO:0042791=PMID:17409385, GO:0006383=Reactome:REACT_1371, GO:0003677=PMID:17409385, GO:0006351=PMID:17409385} Q9Y5Q8 General transcription factor 3C polypeptide 5 protein 20130213 {GO:0005515=IPI, GO:0010467=TAS, GO:0042797=IC, GO:0000127=IDA, GO:0005654=TAS, GO:0042791=IC, GO:0006383=TAS, GO:0003677=IC, GO:0006351=IC} 5S class rRNA transcription from RNA polymerase III type 1 promoter, gene expression, tRNA transcription from RNA polymerase III promoter, transcription from RNA polymerase III promoter, transcription, DNA-dependent nucleoplasm, transcription factor TFIIIC complex DNA binding, protein binding Human GTF3C6 HGNC UniProtKB {GO:0005515=PMID:17409385, GO:0042797=PMID:17409385, GO:0000127=PMID:17409385, GO:0042791=PMID:17409385, GO:0006383=PMID:17409385, GO:0003677=PMID:17409385, GO:0006351=PMID:17409385} Q969F1 General transcription factor 3C polypeptide 6 protein 20070730 {GO:0005515=IPI, GO:0042797=IC, GO:0000127=IDA, GO:0042791=IC, GO:0006383=IDA, GO:0003677=IDA, GO:0006351=IDA} 5S class rRNA transcription from RNA polymerase III type 1 promoter, tRNA transcription from RNA polymerase III promoter, transcription from RNA polymerase III promoter, transcription, DNA-dependent transcription factor TFIIIC complex DNA binding, protein binding Human UniProtKB:Q9Y5Q8 GTPBP1 PINC UniProtKB {GO:0006184=GO_REF:0000024, GO:0007165=PMID:9070279, GO:0006955=PMID:9070279, GO:0000177=GO_REF:0000024, GO:0003924=GO_REF:0000024, GO:0061014=GO_REF:0000024, GO:0005525=GO_REF:0000037, GO:0005829=GO_REF:0000024} O00178 GTP-binding protein 1 protein 20030904 {GO:0006184=ISS, GO:0007165=TAS, GO:0006955=TAS, GO:0000177=ISS, GO:0003924=ISS, GO:0061014=ISS, GO:0005525=IEA, GO:0005829=ISS} GTP catabolic process, immune response, positive regulation of mRNA catabolic process, signal transduction cytoplasmic exosome (RNase complex), cytosol GTP binding, GTPase activity Human GTPBP10 InterPro UniProtKB {GO:0005739=GO_REF:0000019, GO:0000287=GO_REF:0000002, GO:0005694=GO_REF:0000039, GO:0042254=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000002} F8WCN4 GTP-binding protein 10 protein 20130413 {GO:0005739=IEA, GO:0000287=IEA, GO:0005694=IEA, GO:0042254=IEA, GO:0005730=IEA, GO:0003924=IEA, GO:0005525=IEA} ribosome biogenesis chromosome, mitochondrion, nucleolus GTP binding, GTPase activity, magnesium ion binding Human InterPro:IPR006169 GTPBP2 UniProtKB UniProtKB {GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q9BX10 GTP-binding protein 2 protein 20130413 {GO:0003924=IEA, GO:0005525=IEA} GTP binding, GTPase activity Human UniProtKB-KW:KW-0342 GTPBP3 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0003924=GO_REF:0000002, GO:0005634=GO_REF:0000054, GO:0005525=GO_REF:0000037, GO:0006400=GO_REF:0000002} Q969Y2 tRNA modification GTPase GTPBP3, mitochondrial protein 20110516 {GO:0005739=IDA, GO:0003924=IEA, GO:0005634=IDA, GO:0005525=IEA, GO:0006400=IEA} tRNA modification mitochondrion, nucleus GTP binding, GTPase activity Human GTPBP4 GOC UniProtKB {GO:0005515=PMID:17210637, GO:0048471=PMID:17210637, GO:0031965=GO_REF:0000052, GO:0022408=PMID:17210637, GO:0030336=PMID:17210637, GO:0033342=PMID:17210637, GO:0005794=GO_REF:0000052, GO:0008285=PMID:17210637, GO:0042254=GO_REF:0000037, GO:0050821=PMID:17210637, GO:0005730=GO_REF:0000052, GO:0003924=PMID:17210637, GO:0005634=GO_REF:0000052, GO:0000079=PMID:17210637, GO:0005525=PMID:17210637, GO:0006184=PMID:17210637, GO:0005737=GO_REF:0000052, GO:0031397=PMID:17210637, GO:0008156=PMID:17210637} Q9BZE4 Nucleolar GTP-binding protein 1 protein 20130413 {GO:0005515=IPI, GO:0048471=IDA, GO:0031965=IDA, GO:0022408=IDA, GO:0030336=IDA, GO:0033342=IMP, GO:0005794=IDA, GO:0008285=IMP, GO:0042254=IEA, GO:0050821=IDA, GO:0005730=IDA, GO:0003924=IDA, GO:0005634=IDA, GO:0000079=IDA, GO:0005525=IDA, GO:0006184=IDA, GO:0005737=IDA, GO:0031397=IDA, GO:0008156=IMP} GTP catabolic process, negative regulation of DNA replication, negative regulation of cell migration, negative regulation of cell proliferation, negative regulation of cell-cell adhesion, negative regulation of collagen binding, negative regulation of protein ubiquitination, protein stabilization, regulation of cyclin-dependent protein serine/threonine kinase activity, ribosome biogenesis Golgi apparatus, cytoplasm, nuclear membrane, nucleolus, nucleus, perinuclear region of cytoplasm GTP binding, GTPase activity, protein binding Human GTPBP5 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0000287=GO_REF:0000002, GO:0042254=GO_REF:0000037, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q9H4K7 GTP-binding protein 5 protein 20130413 {GO:0005739=IEA, GO:0000287=IEA, GO:0042254=IEA, GO:0003924=IEA, GO:0005525=IEA} ribosome biogenesis mitochondrion GTP binding, GTPase activity, magnesium ion binding Human UniProtKB-SubCell:SL-0173 GTPBP6 UniProtKB UniProtKB {GO:0005525=GO_REF:0000037} O43824 Putative GTP-binding protein 6 protein 20130413 {GO:0005525=IEA} GTP binding Human UniProtKB-KW:KW-0342 GTPBP8 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0003924=GO_REF:0000002, GO:0000917=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q8N3Z3 GTP-binding protein 8 protein 20130413 {GO:0005739=IEA, GO:0003924=IEA, GO:0000917=IEA, GO:0005525=IEA} barrier septum assembly mitochondrion GTP binding, GTPase activity Human Ensembl:ENSMUSP00000125352 GTSE1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0000085=PMID:10974554, GO:0005881=PMID:10974554, GO:0007017=PMID:10974554, GO:0006977=PMID:10974554} Q9NYZ3 G2 and S phase-expressed protein 1 protein 20021105 {GO:0003674=ND, GO:0000085=NAS, GO:0005881=NAS, GO:0007017=NAS, GO:0006977=NAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G2 phase of mitotic cell cycle, microtubule-based process cytoplasmic microtubule molecular_function Human GTSF1 ENSEMBL UniProtKB {GO:0005737=GO_REF:0000019, GO:0046872=GO_REF:0000037} Q8WW33 Gametocyte-specific factor 1 protein 20130413 {GO:0005737=IEA, GO:0046872=IEA} cytoplasm metal ion binding Human Ensembl:ENSMUSP00000023129 GUCA1A PINC UniProtKB {GO:0007165=PMID:7983048, GO:0016020=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0007602=GO_REF:0000019, GO:0007601=GO_REF:0000019, GO:0008048=GO_REF:0000019} P43080 Guanylyl cyclase-activating protein 1 protein 20040811 {GO:0007165=NAS, GO:0016020=IEA, GO:0005509=IEA, GO:0007602=IEA, GO:0007601=IEA, GO:0008048=IEA} phototransduction, signal transduction, visual perception membrane calcium ion binding, calcium sensitive guanylate cyclase activator activity Human GUCA1B PINC UniProtKB {GO:0007589=PMID:1327879, GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0007267=PMID:1409606, GO:0007168=PMID:1327879, GO:0007602=GO_REF:0000019, GO:0007601=GO_REF:0000019, GO:0008048=GO_REF:0000019} Q9UMX6 Guanylyl cyclase-activating protein 2 protein 20030904 {GO:0007589=TAS, GO:0005886=IEA, GO:0005509=IEA, GO:0007267=TAS, GO:0007168=TAS, GO:0007602=IEA, GO:0007601=IEA, GO:0008048=IEA} body fluid secretion, cell-cell signaling, phototransduction, receptor guanylyl cyclase signaling pathway, visual perception plasma membrane calcium ion binding, calcium sensitive guanylate cyclase activator activity Human GUCA2A UniProtKB UniProtKB {GO:0007165=GO_REF:0000029, GO:0030250=PMID:8095028, GO:0005179=PMID:7947768, GO:0005576=PMID:8095028} Q02747 Guanylin protein 20030404 {GO:0007165=NAS, GO:0030250=NAS, GO:0005179=NAS, GO:0005576=NAS} signal transduction extracellular region guanylate cyclase activator activity, hormone activity Human GUCA2B PINC UniProtKB {GO:0007589=GO_REF:0000019, GO:0007588=GO_REF:0000019, GO:0006182=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0045776=GO_REF:0000019, GO:0008048=PMID:8605041} Q16661 Guanylate cyclase activator 2B protein 20030904 {GO:0007589=IEA, GO:0007588=IEA, GO:0006182=IEA, GO:0005576=IEA, GO:0045776=IEA, GO:0008048=TAS} body fluid secretion, cGMP biosynthetic process, excretion, negative regulation of blood pressure extracellular region calcium sensitive guanylate cyclase activator activity Human GUCY1A2 Reactome UniProtKB {GO:0035556=GO_REF:0000002, GO:0007165=PMID:1683630, GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000038, GO:0007596=Reactome:REACT_604, GO:0030828=GO_REF:0000019, GO:0004383=GO_REF:0000003, GO:0005525=GO_REF:0000037, GO:0020037=GO_REF:0000002} P33402 Guanylate cyclase soluble subunit alpha-2 protein 20130301 {GO:0035556=IEA, GO:0007165=TAS, GO:0005737=IEA, GO:0000166=IEA, GO:0007596=TAS, GO:0030828=IEA, GO:0004383=IEA, GO:0005525=IEA, GO:0020037=IEA} blood coagulation, intracellular signal transduction, positive regulation of cGMP biosynthetic process, signal transduction cytoplasm GTP binding, guanylate cyclase activity, heme binding, nucleotide binding Human GUCY1A3 Reactome UniProtKB {GO:0007263=PMID:9742212, GO:0052565=GO_REF:0000019, GO:0008015=PMID:9742212, GO:0004383=GO_REF:0000003, GO:0005525=GO_REF:0000037, GO:0060087=GO_REF:0000019, GO:0035556=GO_REF:0000002, GO:0008074=PMID:1352257, GO:0000166=GO_REF:0000038, GO:0007596=Reactome:REACT_604, GO:0008217=GO_REF:0000019, GO:0030828=GO_REF:0000019, GO:0004872=PMID:9742212, GO:0020037=GO_REF:0000002} Q02108 Guanylate cyclase soluble subunit alpha-3 protein 20130301 {GO:0007263=TAS, GO:0052565=IEA, GO:0008015=TAS, GO:0004383=IEA, GO:0005525=IEA, GO:0060087=IEA, GO:0035556=IEA, GO:0008074=TAS, GO:0000166=IEA, GO:0007596=TAS, GO:0008217=IEA, GO:0030828=IEA, GO:0004872=TAS, GO:0020037=IEA} blood circulation, blood coagulation, intracellular signal transduction, nitric oxide mediated signal transduction, positive regulation of cGMP biosynthetic process, regulation of blood pressure, relaxation of vascular smooth muscle, response to defense-related host nitric oxide production guanylate cyclase complex, soluble GTP binding, guanylate cyclase activity, heme binding, nucleotide binding, receptor activity Human GUCY1B3 HPA UniProtKB {GO:0007263=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0008015=PMID:9742212, GO:0043167=GO_REF:0000019, GO:0051879=GO_REF:0000019, GO:0004383=GO_REF:0000003, GO:0005525=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0035556=GO_REF:0000002, GO:0008074=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0000166=GO_REF:0000038, GO:0007596=Reactome:REACT_604, GO:0004872=PMID:9742212, GO:0020037=GO_REF:0000019} Q02153 Guanylate cyclase soluble subunit beta-1 protein 20101115 {GO:0007263=IEA, GO:0046982=IEA, GO:0008015=TAS, GO:0043167=IEA, GO:0051879=IEA, GO:0004383=IEA, GO:0005525=IEA, GO:0046872=IEA, GO:0043231=IDA, GO:0035556=IEA, GO:0008074=IEA, GO:0005737=IDA, GO:0000166=IEA, GO:0007596=TAS, GO:0004872=TAS, GO:0020037=IEA} blood circulation, blood coagulation, intracellular signal transduction, nitric oxide mediated signal transduction cytoplasm, guanylate cyclase complex, soluble, intracellular membrane-bounded organelle GTP binding, Hsp90 protein binding, guanylate cyclase activity, heme binding, ion binding, metal ion binding, nucleotide binding, protein heterodimerization activity, receptor activity Human GUCY2C PINC UniProtKB {GO:0005515=PMID:11950846, GO:0035556=GO_REF:0000002, GO:0004672=GO_REF:0000002, GO:0042127=GO_REF:0000019, GO:0015643=GO_REF:0000019, GO:0009636=GO_REF:0000019, GO:0004383=GO_REF:0000003, GO:0016021=GO_REF:0000037, GO:0007168=PMID:1680854, GO:0005525=GO_REF:0000037, GO:0005524=GO_REF:0000002} P25092 Heat-stable enterotoxin receptor protein 20030904 {GO:0005515=IPI, GO:0035556=IEA, GO:0004672=IEA, GO:0042127=IEA, GO:0015643=IEA, GO:0009636=IEA, GO:0004383=IEA, GO:0016021=IEA, GO:0007168=TAS, GO:0005525=IEA, GO:0005524=IEA} intracellular signal transduction, receptor guanylyl cyclase signaling pathway, regulation of cell proliferation, response to toxic substance integral to membrane ATP binding, GTP binding, guanylate cyclase activity, protein binding, protein kinase activity, toxic substance binding Human GUCY2D PINC UniProtKB {GO:0005640=PMID:7777544, GO:0035556=GO_REF:0000002, GO:0004672=GO_REF:0000002, GO:0005887=PMID:1356371, GO:0004872=PMID:1356371, GO:0004383=GO_REF:0000003, GO:0007168=PMID:1356371, GO:0005525=GO_REF:0000037, GO:0007601=GO_REF:0000037, GO:0005524=GO_REF:0000002, GO:0042802=GO_REF:0000019} Q02846 Retinal guanylyl cyclase 1 protein 20031119 {GO:0005640=TAS, GO:0035556=IEA, GO:0004672=IEA, GO:0005887=TAS, GO:0004872=TAS, GO:0004383=IEA, GO:0007168=TAS, GO:0005525=IEA, GO:0007601=IEA, GO:0005524=IEA, GO:0042802=IEA} intracellular signal transduction, receptor guanylyl cyclase signaling pathway, visual perception integral to plasma membrane, nuclear outer membrane ATP binding, GTP binding, guanylate cyclase activity, identical protein binding, protein kinase activity, receptor activity Human GUCY2F PINC UniProtKB {GO:0005640=PMID:7777544, GO:0035556=GO_REF:0000002, GO:0004672=GO_REF:0000002, GO:0046982=GO_REF:0000019, GO:0005887=PMID:7777544, GO:0004872=PMID:7777544, GO:0004383=GO_REF:0000003, GO:0007168=PMID:7777544, GO:0005525=GO_REF:0000037, GO:0007601=GO_REF:0000037, GO:0005524=GO_REF:0000002, GO:0042803=GO_REF:0000019} P51841 Retinal guanylyl cyclase 2 protein 20030904 {GO:0005640=TAS, GO:0035556=IEA, GO:0004672=IEA, GO:0046982=IEA, GO:0005887=TAS, GO:0004872=TAS, GO:0004383=IEA, GO:0007168=TAS, GO:0005525=IEA, GO:0007601=IEA, GO:0005524=IEA, GO:0042803=IEA} intracellular signal transduction, receptor guanylyl cyclase signaling pathway, visual perception integral to plasma membrane, nuclear outer membrane ATP binding, GTP binding, guanylate cyclase activity, protein heterodimerization activity, protein homodimerization activity, protein kinase activity, receptor activity Human GUF1 UniProtKB UniProtKB {GO:0005759=GO_REF:0000020, GO:0005743=GO_REF:0000039, GO:0003924=GO_REF:0000020, GO:0043022=GO_REF:0000020, GO:0045727=GO_REF:0000020, GO:0005525=GO_REF:0000020, GO:0006412=GO_REF:0000037} Q8N442 Translation factor GUF1, mitochondrial protein 20130413 {GO:0005759=IEA, GO:0005743=IEA, GO:0003924=IEA, GO:0043022=IEA, GO:0045727=IEA, GO:0005525=IEA, GO:0006412=IEA} positive regulation of translation, translation mitochondrial inner membrane, mitochondrial matrix GTP binding, GTPase activity, ribosome binding Human UniProtKB-SubCell:SL-0168 GUK1 Reactome UniProtKB {GO:0015949=Reactome:REACT_21330, GO:0017144=Reactome:REACT_121388, GO:0004385=PMID:8663313, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0006163=PMID:8663313, GO:0005829=Reactome:REACT_1606} Q16774 Guanylate kinase protein 20130301 {GO:0015949=TAS, GO:0017144=TAS, GO:0004385=IDA, GO:0055086=TAS, GO:0044281=TAS, GO:0005524=IEA, GO:0006163=IDA, GO:0005829=TAS} drug metabolic process, nucleobase-containing small molecule interconversion, nucleobase-containing small molecule metabolic process, purine nucleotide metabolic process, small molecule metabolic process cytosol ATP binding, guanylate kinase activity Human GULP1 GOC UniProtKB {GO:0007165=PMID:10574771, GO:0005737=GO_REF:0000052, GO:0006869=GO_REF:0000037, GO:0006915=GO_REF:0000037, GO:0004871=PMID:10574771, GO:0006911=PMID:11729193} Q9UBP9 PTB domain-containing engulfment adapter protein 1 protein 20130413 {GO:0007165=TAS, GO:0005737=IDA, GO:0006869=IEA, GO:0006915=IEA, GO:0004871=TAS, GO:0006911=IDA} apoptotic process, lipid transport, phagocytosis, engulfment, signal transduction cytoplasm signal transducer activity Human GUSB HPA UniProtKB {GO:0004566=Reactome:REACT_121353, GO:0005975=Reactome:REACT_474, GO:0030212=Reactome:REACT_121083, GO:0006027=Reactome:REACT_120752, GO:0044281=Reactome:REACT_111217, GO:0030214=Reactome:REACT_120996, GO:0030203=Reactome:REACT_121315, GO:0004553=GO_REF:0000002, GO:0043231=GO_REF:0000052, GO:0043202=Reactome:REACT_121353} P08236 Beta-glucuronidase protein 20111111 {GO:0004566=TAS, GO:0005975=TAS, GO:0030212=TAS, GO:0006027=TAS, GO:0044281=TAS, GO:0030214=TAS, GO:0030203=TAS, GO:0004553=IEA, GO:0043231=IDA, GO:0043202=TAS} carbohydrate metabolic process, glycosaminoglycan catabolic process, glycosaminoglycan metabolic process, hyaluronan catabolic process, hyaluronan metabolic process, small molecule metabolic process intracellular membrane-bounded organelle, lysosomal lumen beta-glucuronidase activity, hydrolase activity, hydrolyzing O-glycosyl compounds Human GXYLT1 Reactome UniProtKB {GO:0035252=PMID:19940119, GO:0000139=Reactome:REACT_120955, GO:0005975=Reactome:REACT_474, GO:0016266=PMID:19940119, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408} Q4G148 Glucoside xylosyltransferase 1 protein 20130301 {GO:0035252=IDA, GO:0000139=TAS, GO:0005975=TAS, GO:0016266=IDA, GO:0044281=TAS, GO:0016021=IEA, GO:0030204=TAS, GO:0030203=TAS} O-glycan processing, carbohydrate metabolic process, chondroitin sulfate metabolic process, glycosaminoglycan metabolic process, small molecule metabolic process Golgi membrane, integral to membrane UDP-xylosyltransferase activity Human GYG1 IntAct UniProtKB {GO:0005515=PMID:17055998, GO:0005975=Reactome:REACT_474, GO:0016757=GO_REF:0000002, GO:0005978=Reactome:REACT_1736, GO:0006006=Reactome:REACT_723, GO:0008466=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0005980=Reactome:REACT_1008, GO:0046872=GO_REF:0000037, GO:0005536=GO_REF:0000019, GO:0005829=Reactome:REACT_1902} P46976 Glycogenin-1 protein 20130415 {GO:0005515=IPI, GO:0005975=TAS, GO:0016757=IEA, GO:0005978=TAS, GO:0006006=TAS, GO:0008466=IEA, GO:0044281=TAS, GO:0005980=TAS, GO:0046872=IEA, GO:0005536=IEA, GO:0005829=TAS} carbohydrate metabolic process, glucose metabolic process, glycogen biosynthetic process, glycogen catabolic process, small molecule metabolic process cytosol glucose binding, glycogenin glucosyltransferase activity, metal ion binding, protein binding, transferase activity, transferring glycosyl groups Human UniProtKB:P13807 GYG2 Reactome UniProtKB {GO:0005975=Reactome:REACT_474, GO:0016757=GO_REF:0000002, GO:0005978=Reactome:REACT_1736, GO:0006006=Reactome:REACT_723, GO:0008466=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0005980=Reactome:REACT_1008, GO:0005829=Reactome:REACT_21313} O15488 Glycogenin-2 protein 20130213 {GO:0005975=TAS, GO:0016757=IEA, GO:0005978=TAS, GO:0006006=TAS, GO:0008466=IEA, GO:0044281=TAS, GO:0005980=TAS, GO:0005829=TAS} carbohydrate metabolic process, glucose metabolic process, glycogen biosynthetic process, glycogen catabolic process, small molecule metabolic process cytosol glycogenin glucosyltransferase activity, transferase activity, transferring glycosyl groups Human GYLTL1B UniProtKB UniProtKB {GO:0000139=GO_REF:0000039, GO:0016757=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0046716=GO_REF:0000024} Q8N3Y3 Glycosyltransferase-like protein LARGE2 protein 20041006 {GO:0000139=IEA, GO:0016757=IEA, GO:0016021=IEA, GO:0046716=ISS} muscle cell homeostasis Golgi membrane, integral to membrane transferase activity, transferring glycosyl groups Human UniProtKB:Q9Z1M7 GYPA IntAct UniProtKB {GO:0005886=PMID:8245024, GO:0016020=PMID:3456608, GO:0047484=GO_REF:0000019, GO:0005887=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0016021=GO_REF:0000002, GO:0007016=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0009897=GO_REF:0000019, GO:0042802=PMID:15067009} P02724 Glycophorin-A protein 20130415 {GO:0005886=TAS, GO:0016020=TAS, GO:0047484=IEA, GO:0005887=IEA, GO:0019048=IEA, GO:0016021=IEA, GO:0007016=IEA, GO:0042803=IEA, GO:0009897=IEA, GO:0042802=IPI} cytoskeletal anchoring at plasma membrane, regulation of response to osmotic stress, virus-host interaction external side of plasma membrane, integral to membrane, integral to plasma membrane, membrane, plasma membrane identical protein binding, protein homodimerization activity Human UniProtKB:P02724 GYPB PINC UniProtKB {GO:0005886=PMID:2734312, GO:0005887=PMID:7622054, GO:0016021=GO_REF:0000002} P06028 Glycophorin-B protein 20030904 {GO:0005886=TAS, GO:0005887=TAS, GO:0016021=IEA} integral to membrane, integral to plasma membrane, plasma membrane Human GYPC PINC UniProtKB {GO:0005515=PMID:16669616, GO:0005886=PMID:8219208, GO:0005887=PMID:2416746, GO:0030863=PMID:16669616} P04921 Glycophorin-C protein 20030904 {GO:0005515=IPI, GO:0005886=NAS, GO:0005887=TAS, GO:0030863=IDA} cortical cytoskeleton, integral to plasma membrane, plasma membrane protein binding Human GYS1 IntAct UniProtKB {GO:0005515=PMID:17055998, GO:0007507=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0019901=PMID:16275910, GO:0005975=Reactome:REACT_474, GO:0016234=GO_REF:0000019, GO:0005978=Reactome:REACT_1736, GO:0006006=Reactome:REACT_723, GO:0044281=Reactome:REACT_111217, GO:0004373=PMID:16275910, GO:0005536=GO_REF:0000019, GO:0005829=Reactome:REACT_1169} P13807 "Glycogen ""starch"" synthase, muscle" protein 20130415 {GO:0005515=IPI, GO:0007507=IEA, GO:0005737=IEA, GO:0019901=IPI, GO:0005975=TAS, GO:0016234=IEA, GO:0005978=TAS, GO:0006006=TAS, GO:0044281=TAS, GO:0004373=IDA, GO:0005536=IEA, GO:0005829=TAS} carbohydrate metabolic process, glucose metabolic process, glycogen biosynthetic process, heart development, small molecule metabolic process cytoplasm, cytosol, inclusion body glucose binding, glycogen (starch) synthase activity, protein binding, protein kinase binding Human UniProtKB:P46976 GYS2 Reactome UniProtKB {GO:0005975=Reactome:REACT_474, GO:0005978=Reactome:REACT_1736, GO:0043265=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0006091=PMID:9691087, GO:0004373=GO_REF:0000024, GO:0042803=PMID:9691087, GO:0005829=Reactome:REACT_1169, GO:0009749=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0006006=Reactome:REACT_723, GO:0030864=GO_REF:0000024, GO:0005856=GO_REF:0000024, GO:0005938=GO_REF:0000024} P54840 "Glycogen ""starch"" synthase, liver" protein 20130213 {GO:0005975=TAS, GO:0005978=TAS, GO:0043265=ISS, GO:0044281=TAS, GO:0006091=TAS, GO:0004373=ISS, GO:0042803=TAS, GO:0005829=TAS, GO:0009749=ISS, GO:0005737=ISS, GO:0006006=TAS, GO:0030864=ISS, GO:0005856=ISS, GO:0005938=ISS} carbohydrate metabolic process, generation of precursor metabolites and energy, glucose metabolic process, glycogen biosynthetic process, response to glucose stimulus, small molecule metabolic process cell cortex, cortical actin cytoskeleton, cytoplasm, cytoskeleton, cytosol, ectoplasm glycogen (starch) synthase activity, protein homodimerization activity Human GZF1 UniProtKB UniProtKB {GO:0043565=PMID:16049025, GO:0001658=GO_REF:0000019, GO:0005730=GO_REF:0000039, GO:0005654=GO_REF:0000039, GO:0005634=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0000122=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0045892=PMID:16049025, GO:0006351=GO_REF:0000037} Q9H116 GDNF-inducible zinc finger protein 1 protein 20110428 {GO:0043565=IDA, GO:0001658=IEA, GO:0005730=IEA, GO:0005654=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0000122=IEA, GO:0003676=IEA, GO:0045892=IDA, GO:0006351=IEA} branching involved in ureteric bud morphogenesis, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus, nucleoplasm, nucleus nucleic acid binding, sequence-specific DNA binding, zinc ion binding Human GZMA UniProtKB UniProtKB {GO:0005515=PMID:12524539, GO:0001772=PMID:12524539, GO:0043065=PMID:12524539, GO:0004252=PMID:12819770, GO:0051354=PMID:12524539, GO:0006915=PMID:12524539, GO:0005576=GO_REF:0000039, GO:0005634=PMID:11909973, GO:0042803=PMID:12819770, GO:0006922=PMID:11331782, GO:0043392=PMID:12524539, GO:0006955=PMID:12524539, GO:0032078=PMID:12524539, GO:0051603=PMID:12524539, GO:0019835=GO_REF:0000037} P12544 Granzyme A protein 20040709 {GO:0005515=IPI, GO:0001772=TAS, GO:0043065=IDA, GO:0004252=IDA, GO:0051354=IDA, GO:0006915=TAS, GO:0005576=IEA, GO:0005634=TAS, GO:0042803=IDA, GO:0006922=IDA, GO:0043392=IDA, GO:0006955=TAS, GO:0032078=IDA, GO:0051603=IDA, GO:0019835=IEA} apoptotic process, cleavage of lamin involved in execution phase of apoptosis, cytolysis, immune response, negative regulation of DNA binding, negative regulation of endodeoxyribonuclease activity, negative regulation of oxidoreductase activity, positive regulation of apoptotic process, proteolysis involved in cellular protein catabolic process extracellular region, immunological synapse, nucleus protein binding, protein homodimerization activity, serine-type endopeptidase activity Human UniProtKB:P27695 GZMB HPA UniProtKB {GO:0001772=PMID:12524539, GO:0005515=PMID:16267761, GO:0004252=PMID:12524539, GO:0006915=Reactome:REACT_578, GO:0005634=PMID:11909973, GO:0097193=Reactome:REACT_964, GO:0043231=GO_REF:0000052, GO:0006922=PMID:11331782, GO:0005829=Reactome:REACT_1610, GO:0005737=GO_REF:0000052, GO:1900740=Reactome:REACT_701, GO:0019835=GO_REF:0000037, GO:0006508=GO_REF:0000038, GO:0008236=PMID:2402757} P10144 Granzyme B protein 20101115 {GO:0001772=TAS, GO:0005515=IPI, GO:0004252=TAS, GO:0006915=TAS, GO:0005634=TAS, GO:0097193=TAS, GO:0043231=IDA, GO:0006922=IDA, GO:0005829=TAS, GO:0005737=IDA, GO:1900740=TAS, GO:0019835=IEA, GO:0006508=IEA, GO:0008236=TAS} apoptotic process, cleavage of lamin involved in execution phase of apoptosis, cytolysis, intrinsic apoptotic signaling pathway, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, proteolysis cytoplasm, cytosol, immunological synapse, intracellular membrane-bounded organelle, nucleus protein binding, serine-type endopeptidase activity, serine-type peptidase activity Human GZMH InterPro UniProtKB {GO:0005737=GO_REF:0000029, GO:0004252=GO_REF:0000002, GO:0019835=GO_REF:0000037, GO:0006508=GO_REF:0000002, GO:0006915=PMID:2402757} Q6XGZ1 Granzyme H splice variant 2 protein 20130413 {GO:0005737=NAS, GO:0004252=IEA, GO:0019835=IEA, GO:0006508=IEA, GO:0006915=NAS} apoptotic process, cytolysis, proteolysis cytoplasm serine-type endopeptidase activity Human InterPro:IPR001254|InterPro:IPR018114 GZMK PINC UniProtKB {GO:0004252=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0008236=PMID:8656064, GO:0005576=GO_REF:0000039} P49863 Granzyme K protein 20030904 {GO:0004252=IEA, GO:0006508=IEA, GO:0008236=TAS, GO:0005576=IEA} proteolysis extracellular region serine-type endopeptidase activity, serine-type peptidase activity Human GZMM PINC UniProtKB {GO:0004252=GO_REF:0000002, GO:0045087=GO_REF:0000037, GO:0019835=GO_REF:0000019, GO:0006508=GO_REF:0000037, GO:0008236=PMID:7713495, GO:0006915=GO_REF:0000037, GO:0005576=GO_REF:0000039} P51124 Granzyme M protein 20030904 {GO:0004252=IEA, GO:0045087=IEA, GO:0019835=IEA, GO:0006508=IEA, GO:0008236=TAS, GO:0006915=IEA, GO:0005576=IEA} apoptotic process, cytolysis, innate immune response, proteolysis extracellular region serine-type endopeptidase activity, serine-type peptidase activity Human H1F0 HPA UniProtKB {GO:0000790=PMID:19882353, GO:0005794=GO_REF:0000052, GO:0006309=Reactome:REACT_1213, GO:0006334=GO_REF:0000002, GO:0006915=Reactome:REACT_578, GO:0005634=GO_REF:0000052, GO:0005654=Reactome:REACT_13702, GO:0000786=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006921=Reactome:REACT_995} P07305 Histone H1.0 protein 20111111 {GO:0000790=IDA, GO:0005794=IDA, GO:0006309=TAS, GO:0006334=IEA, GO:0006915=TAS, GO:0005634=IDA, GO:0005654=TAS, GO:0000786=IEA, GO:0003677=IEA, GO:0006921=TAS} apoptotic DNA fragmentation, apoptotic process, cellular component disassembly involved in execution phase of apoptosis, nucleosome assembly Golgi apparatus, nuclear chromatin, nucleoplasm, nucleosome, nucleus DNA binding Human H1FX UniProtKB UniProtKB {GO:0006334=GO_REF:0000029, GO:0005634=GO_REF:0000039, GO:0000786=GO_REF:0000029, GO:0003677=GO_REF:0000029} Q92522 Histone H1x protein 20030424 {GO:0006334=NAS, GO:0005634=IEA, GO:0000786=NAS, GO:0003677=NAS} nucleosome assembly nucleosome, nucleus DNA binding Human H2AFB1 UniProtKB UniProtKB {GO:0006397=PMID:22795134, GO:0046982=GO_REF:0000002, GO:0006334=PMID:22795134, GO:0035327=PMID:22795134, GO:0000788=PMID:22795134, GO:0003677=GO_REF:0000037} P0C5Y9 Histone H2A-Bbd type 1 protein 20120824 {GO:0006397=IMP, GO:0046982=IEA, GO:0006334=IDA, GO:0035327=IDA, GO:0000788=IDA, GO:0003677=IEA} mRNA processing, nucleosome assembly nuclear nucleosome, transcriptionally active chromatin DNA binding, protein heterodimerization activity Human H2AFB2 UniProtKB UniProtKB {GO:0006397=PMID:22795134, GO:0046982=GO_REF:0000002, GO:0006334=PMID:22795134, GO:0035327=PMID:22795134, GO:0000788=PMID:22795134, GO:0003677=GO_REF:0000037} P0C5Z0 Histone H2A-Bbd type 2/3 protein 20120824 {GO:0006397=IMP, GO:0046982=IEA, GO:0006334=IDA, GO:0035327=IDA, GO:0000788=IDA, GO:0003677=IEA} mRNA processing, nucleosome assembly nuclear nucleosome, transcriptionally active chromatin DNA binding, protein heterodimerization activity Human H2AFB3 null null {} null null null null {} null null null H2AFJ UniProtKB UniProtKB {GO:0046982=GO_REF:0000002, GO:0006334=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0000786=GO_REF:0000037, GO:0003677=GO_REF:0000037} Q9BTM1 Histone H2A.J protein 20130413 {GO:0046982=IEA, GO:0006334=IEA, GO:0005634=IEA, GO:0000786=IEA, GO:0003677=IEA} nucleosome assembly nucleosome, nucleus DNA binding, protein heterodimerization activity Human UniProtKB-SubCell:SL-0191 H2AFV UniProtKB UniProtKB {GO:0046982=GO_REF:0000002, GO:0006334=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0000786=GO_REF:0000037, GO:0003677=GO_REF:0000037} Q71UI9 Histone H2A.V protein 20130413 {GO:0046982=IEA, GO:0006334=IEA, GO:0005634=IEA, GO:0000786=IEA, GO:0003677=IEA} nucleosome assembly nucleosome, nucleus DNA binding, protein heterodimerization activity Human UniProtKB-SubCell:SL-0191 H2AFX BHF-UCL UniProtKB {GO:0005515=PMID:20360685, GO:0000790=GO_REF:0000019, GO:0005657=GO_REF:0000019, GO:0005634=PMID:15604234, GO:0007283=GO_REF:0000019, GO:0045739=PMID:19234442, GO:0006302=Reactome:REACT_2054, GO:0042393=PMID:19234442, GO:0000724=Reactome:REACT_1874, GO:0010212=PMID:19234442, GO:0000786=GO_REF:0000029, GO:0001741=GO_REF:0000019, GO:0000794=GO_REF:0000019, GO:0000781=PMID:15149599, GO:0046982=GO_REF:0000002, GO:0006334=PMID:2587254, GO:0003677=PMID:2587254, GO:0006974=PMID:15149599, GO:0003684=GO_REF:0000019, GO:0007126=GO_REF:0000037, GO:0006281=Reactome:REACT_216, GO:0005654=Reactome:REACT_1809, GO:0000077=PMID:17974976, GO:0019899=PMID:19234442, GO:0001673=GO_REF:0000019} P16104 Histone H2A.x protein 20101202 {GO:0005515=IPI, GO:0000790=IEA, GO:0005657=IEA, GO:0005634=IDA, GO:0007283=IEA, GO:0045739=NAS, GO:0006302=TAS, GO:0042393=IPI, GO:0000724=TAS, GO:0010212=NAS, GO:0000786=NAS, GO:0001741=IEA, GO:0000794=IEA, GO:0000781=IDA, GO:0046982=IEA, GO:0006334=NAS, GO:0003677=NAS, GO:0006974=IDA, GO:0003684=IEA, GO:0007126=IEA, GO:0006281=TAS, GO:0005654=TAS, GO:0000077=IDA, GO:0019899=IPI, GO:0001673=IEA} DNA damage checkpoint, DNA repair, double-strand break repair, double-strand break repair via homologous recombination, meiosis, nucleosome assembly, positive regulation of DNA repair, response to DNA damage stimulus, response to ionizing radiation, spermatogenesis XY body, chromosome, telomeric region, condensed nuclear chromosome, male germ cell nucleus, nuclear chromatin, nucleoplasm, nucleosome, nucleus, replication fork DNA binding, damaged DNA binding, enzyme binding, histone binding, protein binding, protein heterodimerization activity colocalizes_with Human H2AFY MGI UniProtKB {GO:0001740=PMID:11331621, GO:0000793=GO_REF:0000019, GO:0046982=GO_REF:0000002, GO:0003682=GO_REF:0000019, GO:0006334=PMID:9714746, GO:0005634=GO_REF:0000040, GO:0007549=PMID:15053874, GO:0000786=PMID:9714746, GO:0003677=PMID:9714746, GO:0016568=GO_REF:0000037} O75367 Core histone macro-H2A.1 protein 20040629 {GO:0001740=IDA, GO:0000793=IEA, GO:0046982=IEA, GO:0003682=IEA, GO:0006334=NAS, GO:0005634=IEA, GO:0007549=IDA, GO:0000786=NAS, GO:0003677=NAS, GO:0016568=IEA} chromatin modification, dosage compensation, nucleosome assembly Barr body, condensed chromosome, nucleosome, nucleus DNA binding, chromatin binding, protein heterodimerization activity Human H2AFY2 HPA UniProtKB {GO:0001740=PMID:11331621, GO:0046982=GO_REF:0000002, GO:0006334=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0007549=PMID:11331621, GO:0000786=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q9P0M6 Core histone macro-H2A.2 protein 20110516 {GO:0001740=IDA, GO:0046982=IEA, GO:0006334=IEA, GO:0005634=IDA, GO:0007549=IDA, GO:0000786=IEA, GO:0003677=IEA, GO:0016568=IEA} chromatin modification, dosage compensation, nucleosome assembly Barr body, nucleosome, nucleus DNA binding, protein heterodimerization activity Human H2AFZ MGI UniProtKB {GO:0001740=PMID:11331621, GO:0046982=GO_REF:0000002, GO:0006334=GO_REF:0000002, GO:0005634=PMID:11331621, GO:0000786=GO_REF:0000037, GO:0003677=GO_REF:0000037} P0C0S5 Histone H2A.Z protein 20091116 {GO:0001740=IDA, GO:0046982=IEA, GO:0006334=IEA, GO:0005634=IDA, GO:0000786=IEA, GO:0003677=IEA} nucleosome assembly Barr body, nucleosome, nucleus DNA binding, protein heterodimerization activity Human H2BFM HPA UniProtKB {GO:0046982=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0006334=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0000786=GO_REF:0000037, GO:0003677=GO_REF:0000037} P0C1H6 Histone H2B type F-M protein 20111111 {GO:0046982=IEA, GO:0005730=IDA, GO:0006334=IEA, GO:0005634=IDA, GO:0000786=IEA, GO:0003677=IEA} nucleosome assembly nucleolus, nucleosome, nucleus DNA binding, protein heterodimerization activity NOT Human H3F3A Reactome UniProtKB {GO:0046982=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0006334=GO_REF:0000002, GO:0005654=Reactome:REACT_25371, GO:0005576=Reactome:REACT_75858, GO:0005634=GO_REF:0000038, GO:0000786=GO_REF:0000037, GO:0003677=GO_REF:0000037} P84243 Histone H3.3 protein 20130301 {GO:0046982=IEA, GO:0007596=TAS, GO:0006334=IEA, GO:0005654=TAS, GO:0005576=TAS, GO:0005634=IEA, GO:0000786=IEA, GO:0003677=IEA} blood coagulation, nucleosome assembly extracellular region, nucleoplasm, nucleosome, nucleus DNA binding, protein heterodimerization activity Human H3F3B UniProtKB UniProtKB {GO:0046982=GO_REF:0000002, GO:0006334=GO_REF:0000002, GO:0005634=GO_REF:0000038, GO:0000786=GO_REF:0000002, GO:0003677=GO_REF:0000038} K7ES00 Histone H3.3 protein 20130413 {GO:0046982=IEA, GO:0006334=IEA, GO:0005634=IEA, GO:0000786=IEA, GO:0003677=IEA} nucleosome assembly nucleosome, nucleus DNA binding, protein heterodimerization activity Human UniProtKB-KW:KW-0539 H3F3C UniProtKB UniProtKB {GO:0046982=GO_REF:0000002, GO:0006334=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0000786=GO_REF:0000037, GO:0003677=GO_REF:0000037} Q6NXT2 Histone H3.3C protein 20130413 {GO:0046982=IEA, GO:0006334=IEA, GO:0005634=IEA, GO:0000786=IEA, GO:0003677=IEA} nucleosome assembly nucleosome, nucleus DNA binding, protein heterodimerization activity Human UniProtKB-SubCell:SL-0191 H6PD UniProtKB UniProtKB {GO:0050661=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0047936=GO_REF:0000003, GO:0004345=GO_REF:0000019, GO:0005788=GO_REF:0000039, GO:0030246=GO_REF:0000019, GO:0017057=GO_REF:0000003, GO:0097305=GO_REF:0000019, GO:0006098=GO_REF:0000019} O95479 GDH/6PGL endoplasmic bifunctional protein protein 20130413 {GO:0050661=IEA, GO:0005739=IEA, GO:0047936=IEA, GO:0004345=IEA, GO:0005788=IEA, GO:0030246=IEA, GO:0017057=IEA, GO:0097305=IEA, GO:0006098=IEA} pentose-phosphate shunt, response to alcohol endoplasmic reticulum lumen, mitochondrion "6-phosphogluconolactonase activity, NADP binding, carbohydrate binding, glucose 1-dehydrogenase NAD(P)"" activity, glucose-6-phosphate dehydrogenase activity""" Human UniProtKB-SubCell:SL-0096 HAAO Reactome UniProtKB {GO:0006569=Reactome:REACT_916, GO:0031966=GO_REF:0000019, GO:0005506=GO_REF:0000019, GO:0000334=Reactome:REACT_612, GO:0009055=PMID:7514594, GO:0044281=Reactome:REACT_111217, GO:0010043=PMID:12007609, GO:0008198=PMID:12007609, GO:0005829=Reactome:REACT_612, GO:0034641=Reactome:REACT_13, GO:0019805=PMID:7514594, GO:0019825=GO_REF:0000019, GO:0046874=GO_REF:0000019, GO:0009435=GO_REF:0000041, GO:0070050=PMID:2967497, GO:0046686=PMID:12007609} P46952 3-hydroxyanthranilate 3,4-dioxygenase protein 20130213 {GO:0006569=TAS, GO:0031966=IEA, GO:0005506=IEA, GO:0000334=TAS, GO:0009055=NAS, GO:0044281=TAS, GO:0010043=IDA, GO:0008198=IDA, GO:0005829=TAS, GO:0034641=TAS, GO:0019805=NAS, GO:0019825=IEA, GO:0046874=IEA, GO:0009435=IEA, GO:0070050=IMP, GO:0046686=IDA} NAD biosynthetic process, cellular nitrogen compound metabolic process, neuron homeostasis, quinolinate biosynthetic process, quinolinate metabolic process, response to cadmium ion, response to zinc ion, small molecule metabolic process, tryptophan catabolic process cytosol, mitochondrial membrane 3-hydroxyanthranilate 3,4-dioxygenase activity, electron carrier activity, ferrous iron binding, iron ion binding, oxygen binding Human HABP2 PINC UniProtKB {GO:0004252=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0005576=PMID:14718574, GO:0005539=PMID:8827452, GO:0007155=PMID:8827452, GO:0005615=PMID:8827452} Q14520 Hyaluronan-binding protein 2 protein 20030904 {GO:0004252=IEA, GO:0006508=IEA, GO:0005576=NAS, GO:0005539=TAS, GO:0007155=TAS, GO:0005615=TAS} cell adhesion, proteolysis extracellular region, extracellular space glycosaminoglycan binding, serine-type endopeptidase activity Human HABP4 IntAct UniProtKB {GO:0005515=PMID:16169070, GO:0006355=GO_REF:0000037, GO:0030168=Reactome:REACT_798, GO:0005634=GO_REF:0000024, GO:0005576=Reactome:REACT_21347, GO:0030017=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0043392=PMID:15862299, GO:0005829=Reactome:REACT_21347, GO:0005737=GO_REF:0000024, GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0071260=GO_REF:0000024} Q5JVS0 Intracellular hyaluronan-binding protein 4 protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0030168=TAS, GO:0005634=ISS, GO:0005576=TAS, GO:0030017=ISS, GO:0006351=IEA, GO:0043392=IDA, GO:0005829=TAS, GO:0005737=ISS, GO:0007596=TAS, GO:0002576=TAS, GO:0071260=ISS} blood coagulation, cellular response to mechanical stimulus, negative regulation of DNA binding, platelet activation, platelet degranulation, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, cytosol, extracellular region, nucleus, sarcomere protein binding Human UniProtKB:Q99873 HACE1 UniProtKB UniProtKB {GO:0030334=PMID:22036506, GO:0004842=PMID:22036506, GO:0006355=GO_REF:0000037, GO:0017137=PMID:21988917, GO:0016567=PMID:21988917, GO:0005783=GO_REF:0000039, GO:0005634=GO_REF:0000033, GO:0006351=GO_REF:0000037, GO:0005622=GO_REF:0000002, GO:0048365=PMID:22036506, GO:0016601=PMID:22036506, GO:0007049=GO_REF:0000037, GO:0000139=PMID:21988917, GO:0006944=PMID:21988917, GO:0042787=PMID:22036506, GO:0032580=GO_REF:0000039, GO:0007030=PMID:21988917, GO:0070936=PMID:22036506} Q8IYU2 E3 ubiquitin-protein ligase HACE1 protein 20120113 {GO:0030334=IMP, GO:0004842=IDA, GO:0006355=IEA, GO:0017137=IDA, GO:0016567=IDA, GO:0005783=IEA, GO:0005634=IBA, GO:0006351=IEA, GO:0005622=IEA, GO:0048365=IPI, GO:0016601=TAS, GO:0007049=IEA, GO:0000139=IDA, GO:0006944=IMP, GO:0042787=IDA, GO:0032580=IEA, GO:0007030=IDA, GO:0070936=IDA} Golgi organization, Rac protein signal transduction, cell cycle, cellular membrane fusion, protein K48-linked ubiquitination, protein ubiquitination, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, regulation of cell migration, regulation of transcription, DNA-dependent, transcription, DNA-dependent Golgi cisterna membrane, Golgi membrane, endoplasmic reticulum, intracellular, nucleus Rab GTPase binding, Rac GTPase binding, ubiquitin-protein ligase activity Human HACL1 IntAct UniProtKB {GO:0048037=PMID:15644336, GO:0000287=GO_REF:0000002, GO:0005782=Reactome:REACT_17035, GO:0005102=PMID:20178365, GO:0044281=Reactome:REACT_111217, GO:0030976=PMID:10468558, GO:0003824=GO_REF:0000002, GO:0051259=PMID:21708296, GO:0016829=GO_REF:0000038, GO:0042802=PMID:16189514, GO:0001561=Reactome:REACT_17003, GO:0016830=Reactome:REACT_17035, GO:0044255=Reactome:REACT_16957, GO:0005777=PMID:14561759} Q9UJ83 2-hydroxyacyl-CoA lyase 1 protein 20130415 {GO:0048037=IDA, GO:0000287=IEA, GO:0005782=TAS, GO:0005102=IPI, GO:0044281=TAS, GO:0030976=IDA, GO:0003824=IEA, GO:0051259=IDA, GO:0016829=IEA, GO:0042802=IPI, GO:0001561=TAS, GO:0016830=TAS, GO:0044255=TAS, GO:0005777=IDA} cellular lipid metabolic process, fatty acid alpha-oxidation, protein oligomerization, small molecule metabolic process peroxisomal matrix, peroxisome carbon-carbon lyase activity, catalytic activity, cofactor binding, identical protein binding, lyase activity, magnesium ion binding, receptor binding, thiamine pyrophosphate binding Human UniProtKB:Q9UJ83 HADH HPA UniProtKB {GO:0014823=GO_REF:0000019, GO:0032868=GO_REF:0000019, GO:0006635=Reactome:REACT_1473, GO:0042493=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005743=GO_REF:0000019, GO:0003857=Reactome:REACT_2195, GO:0070403=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000054, GO:0005759=Reactome:REACT_2195, GO:0006631=GO_REF:0000002, GO:0046676=GO_REF:0000019, GO:0044255=Reactome:REACT_22279} Q16836 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial protein 20110516 {GO:0014823=IEA, GO:0032868=IEA, GO:0006635=TAS, GO:0042493=IEA, GO:0005730=IDA, GO:0005743=IEA, GO:0003857=TAS, GO:0070403=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0005739=IDA, GO:0005737=IDA, GO:0005759=TAS, GO:0006631=IEA, GO:0046676=IEA, GO:0044255=TAS} cellular lipid metabolic process, fatty acid beta-oxidation, fatty acid metabolic process, negative regulation of insulin secretion, response to activity, response to drug, response to insulin stimulus, small molecule metabolic process cytoplasm, mitochondrial inner membrane, mitochondrial matrix, mitochondrion, nucleolus, nucleus 3-hydroxyacyl-CoA dehydrogenase activity, NAD+ binding Human HADHA HPA UniProtKB {GO:0005515=PMID:20562859, GO:0042645=PMID:18063578, GO:0050662=GO_REF:0000002, GO:0005743=Reactome:REACT_120775, GO:0035965=Reactome:REACT_121006, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0032403=GO_REF:0000019, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0051287=GO_REF:0000019, GO:0006631=GO_REF:0000002, GO:0003985=PMID:8135828, GO:0000062=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0032868=GO_REF:0000019, GO:0006635=Reactome:REACT_1473, GO:0042493=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0003857=GO_REF:0000019, GO:0016508=GO_REF:0000019, GO:0016509=GO_REF:0000003, GO:0016507=GO_REF:0000019, GO:0004300=GO_REF:0000003, GO:0006644=Reactome:REACT_120870, GO:0046474=Reactome:REACT_121401} P40939 Trifunctional enzyme subunit alpha, mitochondrial protein 20090616 {GO:0005515=IPI, GO:0042645=IDA, GO:0050662=IEA, GO:0005743=TAS, GO:0035965=TAS, GO:0044281=TAS, GO:0003824=IEA, GO:0032403=IEA, GO:0005739=IDA, GO:0005737=IDA, GO:0051287=IEA, GO:0006631=IEA, GO:0003985=TAS, GO:0000062=IEA, GO:0044255=TAS, GO:0032868=IEA, GO:0006635=TAS, GO:0042493=IEA, GO:0005730=IDA, GO:0003857=IEA, GO:0016508=IEA, GO:0016509=IEA, GO:0016507=IEA, GO:0004300=IEA, GO:0006644=TAS, GO:0046474=TAS} cardiolipin acyl-chain remodeling, cellular lipid metabolic process, fatty acid beta-oxidation, fatty acid metabolic process, glycerophospholipid biosynthetic process, phospholipid metabolic process, response to drug, response to insulin stimulus, small molecule metabolic process cytoplasm, mitochondrial fatty acid beta-oxidation multienzyme complex, mitochondrial inner membrane, mitochondrial nucleoid, mitochondrion, nucleolus 3-hydroxyacyl-CoA dehydrogenase activity, NAD binding, acetyl-CoA C-acetyltransferase activity, catalytic activity, coenzyme binding, enoyl-CoA hydratase activity, fatty-acyl-CoA binding, long-chain-3-hydroxyacyl-CoA dehydrogenase activity, long-chain-enoyl-CoA hydratase activity, protein binding, protein complex binding Human HADHB BHF-UCL UniProtKB {GO:0042645=PMID:18063578, GO:0005515=PMID:20562859, GO:0016747=GO_REF:0000002, GO:0006635=Reactome:REACT_1473, GO:0005783=PMID:21527675, GO:0035965=Reactome:REACT_121006, GO:0005743=Reactome:REACT_120775, GO:0005741=PMID:21527675, GO:0003857=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0005740=PMID:1550553, GO:0032403=GO_REF:0000019, GO:0005739=PMID:7958339, GO:0051287=GO_REF:0000019, GO:0016508=GO_REF:0000019, GO:0016509=GO_REF:0000019, GO:0016507=GO_REF:0000019, GO:0006644=Reactome:REACT_120870, GO:0003988=GO_REF:0000003, GO:0004300=GO_REF:0000019, GO:0000062=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0046474=Reactome:REACT_121401} P55084 Trifunctional enzyme subunit beta, mitochondrial protein 20090218 {GO:0042645=IDA, GO:0005515=IPI, GO:0016747=IEA, GO:0006635=TAS, GO:0005783=IDA, GO:0035965=TAS, GO:0005743=TAS, GO:0005741=IDA, GO:0003857=IEA, GO:0044281=TAS, GO:0005740=TAS, GO:0032403=IEA, GO:0005739=NAS, GO:0051287=IEA, GO:0016508=IEA, GO:0016509=IEA, GO:0016507=IEA, GO:0006644=TAS, GO:0003988=IEA, GO:0004300=IEA, GO:0000062=IEA, GO:0044255=TAS, GO:0046474=TAS} cardiolipin acyl-chain remodeling, cellular lipid metabolic process, fatty acid beta-oxidation, glycerophospholipid biosynthetic process, phospholipid metabolic process, small molecule metabolic process endoplasmic reticulum, mitochondrial envelope, mitochondrial fatty acid beta-oxidation multienzyme complex, mitochondrial inner membrane, mitochondrial nucleoid, mitochondrial outer membrane, mitochondrion 3-hydroxyacyl-CoA dehydrogenase activity, NAD binding, acetyl-CoA C-acyltransferase activity, enoyl-CoA hydratase activity, fatty-acyl-CoA binding, long-chain-3-hydroxyacyl-CoA dehydrogenase activity, long-chain-enoyl-CoA hydratase activity, protein binding, protein complex binding, transferase activity, transferring acyl groups other than amino-acyl groups Human HAGH UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0005759=GO_REF:0000039, GO:0006750=PMID:8550579, GO:0008270=GO_REF:0000002, GO:0004416=PMID:8550579} Q16775 Hydroxyacylglutathione hydrolase, mitochondrial protein 20090807 {GO:0005739=IEA, GO:0005759=IEA, GO:0006750=IDA, GO:0008270=IEA, GO:0004416=IDA} glutathione biosynthetic process mitochondrial matrix, mitochondrion hydroxyacylglutathione hydrolase activity, zinc ion binding Human HAGHL InterPro UniProtKB {GO:0016787=GO_REF:0000002, GO:0006750=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0004416=GO_REF:0000002} Q6PII5 Hydroxyacylglutathione hydrolase-like protein protein 20130413 {GO:0016787=IEA, GO:0006750=IEA, GO:0008270=IEA, GO:0004416=IEA} glutathione biosynthetic process hydrolase activity, hydroxyacylglutathione hydrolase activity, zinc ion binding Human InterPro:IPR017782 HAL InterPro UniProtKB {GO:0034641=Reactome:REACT_13, GO:0019557=GO_REF:0000041, GO:0009058=GO_REF:0000002, GO:0019556=GO_REF:0000041, GO:0006548=Reactome:REACT_1249, GO:0004397=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_1225, GO:0016841=GO_REF:0000002} Q4VB95 HAL protein protein 20130413 {GO:0034641=TAS, GO:0019557=IEA, GO:0009058=IEA, GO:0019556=IEA, GO:0006548=TAS, GO:0004397=IEA, GO:0044281=TAS, GO:0005829=TAS, GO:0016841=IEA} biosynthetic process, cellular nitrogen compound metabolic process, histidine catabolic process, histidine catabolic process to glutamate and formamide, histidine catabolic process to glutamate and formate, small molecule metabolic process cytosol ammonia-lyase activity, histidine ammonia-lyase activity Human InterPro:IPR001106 HAMP UniProtKB UniProtKB {GO:0006879=GO_REF:0000002, GO:0006955=PMID:11113131, GO:0005179=GO_REF:0000037, GO:0050832=GO_REF:0000037, GO:0031640=GO_REF:0000037, GO:0005576=PMID:11034317, GO:0042742=GO_REF:0000037} P81172 Hepcidin protein 20010917 {GO:0006879=IEA, GO:0006955=TAS, GO:0005179=IEA, GO:0050832=IEA, GO:0031640=IEA, GO:0005576=NAS, GO:0042742=IEA} cellular iron ion homeostasis, defense response to bacterium, defense response to fungus, immune response, killing of cells of other organism extracellular region hormone activity Human HAND1 BHF-UCL UniProtKB {GO:0005515=PMID:16043483, GO:0006366=PMID:11802795, GO:0044212=PMID:11802795, GO:0055010=PMID:18276607, GO:0005634=PMID:11802795, GO:0003219=PMID:18276607, GO:0042803=PMID:16043483, GO:0043433=GO_REF:0000019, GO:0003218=PMID:18276607, GO:0042802=GO_REF:0000024, GO:0007507=GO_REF:0000024, GO:0001947=GO_REF:0000024, GO:0005737=PMID:11802795, GO:0045944=PMID:16043483, GO:0003144=GO_REF:0000019, GO:0042475=GO_REF:0000019, GO:0001707=GO_REF:0000019, GO:0035050=GO_REF:0000024, GO:0046982=GO_REF:0000019, GO:0003713=PMID:16043483, GO:0060411=PMID:19586923, GO:0001824=PMID:11802795, GO:0060707=GO_REF:0000019, GO:0005730=GO_REF:0000039, GO:0043425=PMID:11802795, GO:0001525=GO_REF:0000024, GO:0000122=PMID:11802795, GO:0001829=PMID:11802795, GO:0043565=GO_REF:0000019, GO:0005654=GO_REF:0000039, GO:0060485=GO_REF:0000019, GO:0060536=GO_REF:0000019, GO:0019899=GO_REF:0000019, GO:0045892=PMID:11802795, GO:0008134=PMID:16043483} O96004 Heart- and neural crest derivatives-expressed protein 1 protein 20100421 {GO:0005515=IPI, GO:0006366=IDA, GO:0044212=IDA, GO:0055010=IMP, GO:0005634=IDA, GO:0003219=IMP, GO:0042803=NAS, GO:0043433=IEA, GO:0003218=IMP, GO:0042802=ISS, GO:0007507=ISS, GO:0001947=ISS, GO:0005737=IDA, GO:0045944=IDA, GO:0003144=IEA, GO:0042475=IEA, GO:0001707=IEA, GO:0035050=ISS, GO:0046982=IEA, GO:0003713=IDA, GO:0060411=IMP, GO:0001824=IEP, GO:0060707=IEA, GO:0005730=IEA, GO:0043425=IPI, GO:0001525=ISS, GO:0000122=IDA, GO:0001829=IEP, GO:0043565=IEA, GO:0005654=IEA, GO:0060485=IEA, GO:0060536=IEA, GO:0019899=IEA, GO:0045892=IDA, GO:0008134=IPI} angiogenesis, blastocyst development, cardiac left ventricle formation, cardiac right ventricle formation, cardiac septum morphogenesis, cartilage morphogenesis, embryonic heart tube development, embryonic heart tube formation, heart development, heart looping, mesenchyme development, mesoderm formation, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, odontogenesis of dentin-containing tooth, positive regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter, trophectodermal cell differentiation, trophoblast giant cell differentiation, ventricular cardiac muscle tissue morphogenesis cytoplasm, nucleolus, nucleoplasm, nucleus bHLH transcription factor binding, enzyme binding, identical protein binding, protein binding, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding, transcription coactivator activity, transcription factor binding, transcription regulatory region DNA binding Human HAND2 BHF-UCL UniProtKB {GO:0005515=PMID:15486975, GO:0000790=PMID:16280598, GO:0044212=GO_REF:0000024, GO:0010463=GO_REF:0000019, GO:0048538=GO_REF:0000024, GO:0042803=GO_REF:0000024, GO:0007512=PMID:9878849, GO:0007507=PMID:15486975, GO:0001947=GO_REF:0000024, GO:0014032=GO_REF:0000024, GO:0046983=GO_REF:0000002, GO:0010667=GO_REF:0000024, GO:0000977=PMID:16280598, GO:0046982=GO_REF:0000019, GO:0003713=GO_REF:0000024, GO:0070888=GO_REF:0000024, GO:0001701=GO_REF:0000024, GO:0048485=GO_REF:0000019, GO:0043392=GO_REF:0000019, GO:0043234=PMID:15486975, GO:0048935=GO_REF:0000019, GO:0060536=GO_REF:0000019, GO:0043586=GO_REF:0000019, GO:0045893=GO_REF:0000024, GO:2000763=GO_REF:0000024, GO:0061325=GO_REF:0000019, GO:2000764=GO_REF:0000024, GO:0003357=PMID:16280598, GO:0042733=GO_REF:0000019, GO:0008134=GO_REF:0000024, GO:2000679=PMID:16280598, GO:0003219=GO_REF:0000019, GO:0043433=GO_REF:0000019, GO:0001967=GO_REF:0000019, GO:0045944=PMID:16280598, GO:0060021=GO_REF:0000019, GO:0042475=GO_REF:0000019, GO:0033613=GO_REF:0000024, GO:0003266=GO_REF:0000024, GO:0005667=GO_REF:0000024, GO:0006355=GO_REF:0000024, GO:0006915=GO_REF:0000024, GO:0001525=GO_REF:0000037, GO:0001077=PMID:15486975, GO:0003007=GO_REF:0000024, GO:0045668=GO_REF:0000019, GO:0003680=PMID:15486975, GO:0061309=GO_REF:0000024, GO:0060982=GO_REF:0000019, GO:0003253=GO_REF:0000019, GO:0061032=GO_REF:0000019} P61296 Heart- and neural crest derivatives-expressed protein 2 protein 20110618 {GO:0005515=IPI, GO:0000790=IDA, GO:0044212=ISS, GO:0010463=IEA, GO:0048538=ISS, GO:0042803=ISS, GO:0007512=IEP, GO:0007507=NAS, GO:0001947=ISS, GO:0014032=ISS, GO:0046983=IEA, GO:0010667=ISS, GO:0000977=IDA, GO:0046982=IEA, GO:0003713=ISS, GO:0070888=ISS, GO:0001701=ISS, GO:0048485=IEA, GO:0043392=IEA, GO:0043234=IDA, GO:0048935=IEA, GO:0060536=IEA, GO:0043586=IEA, GO:0045893=ISS, GO:2000763=ISS, GO:0061325=IEA, GO:2000764=ISS, GO:0003357=NAS, GO:0042733=IEA, GO:0008134=ISS, GO:2000679=IDA, GO:0003219=IEA, GO:0043433=IEA, GO:0001967=IEA, GO:0045944=IDA, GO:0060021=IEA, GO:0042475=IEA, GO:0033613=ISS, GO:0003266=ISS, GO:0005667=ISS, GO:0006355=ISS, GO:0006915=ISS, GO:0001525=IEA, GO:0001077=IDA, GO:0003007=ISS, GO:0045668=IEA, GO:0003680=IDA, GO:0061309=ISS, GO:0060982=IEA, GO:0003253=IEA, GO:0061032=IEA} adult heart development, angiogenesis, apoptotic process, cardiac neural crest cell development involved in outflow tract morphogenesis, cardiac neural crest cell migration involved in outflow tract morphogenesis, cardiac right ventricle formation, cartilage morphogenesis, cell proliferation involved in outflow tract morphogenesis, coronary artery morphogenesis, embryonic digit morphogenesis, heart development, heart looping, heart morphogenesis, in utero embryonic development, mesenchymal cell proliferation, negative regulation of DNA binding, negative regulation of cardiac muscle cell apoptotic process, negative regulation of osteoblast differentiation, negative regulation of sequence-specific DNA binding transcription factor activity, neural crest cell development, noradrenergic neuron differentiation, odontogenesis of dentin-containing tooth, palate development, peripheral nervous system neuron development, positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process, positive regulation of transcription regulatory region DNA binding, positive regulation of transcription, DNA-dependent, regulation of secondary heart field cardioblast proliferation, regulation of transcription, DNA-dependent, suckling behavior, sympathetic nervous system development, thymus development, tongue development, visceral serous pericardium development nuclear chromatin, protein complex, transcription factor complex AT DNA binding, E-box binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II regulatory region sequence-specific DNA binding, activating transcription factor binding, protein binding, protein dimerization activity, protein heterodimerization activity, protein homodimerization activity, transcription coactivator activity, transcription factor binding, transcription regulatory region DNA binding Human UniProtKB:Q61039 HAO1 Reactome UniProtKB {GO:0052852=GO_REF:0000003, GO:0052853=GO_REF:0000003, GO:0005782=Reactome:REACT_17020, GO:0010181=PMID:18215067, GO:0005102=PMID:20178365, GO:0044281=Reactome:REACT_111217, GO:0052854=GO_REF:0000003, GO:0046296=PMID:18215067, GO:0034641=Reactome:REACT_13, GO:0001561=PMID:18215067, GO:0008891=Reactome:REACT_17020, GO:0003973=PMID:10777549, GO:0047969=Reactome:REACT_16979, GO:0046487=Reactome:REACT_16925, GO:0006979=GO_REF:0000019, GO:0005777=PMID:10777549} Q9UJM8 Hydroxyacid oxidase 1 protein 20100411 {GO:0052852=IEA, GO:0052853=IEA, GO:0005782=TAS, GO:0010181=IDA, GO:0005102=IPI, GO:0044281=TAS, GO:0052854=IEA, GO:0046296=IDA, GO:0034641=TAS, GO:0001561=IDA, GO:0008891=TAS, GO:0003973=IDA, GO:0047969=TAS, GO:0046487=TAS, GO:0006979=IEA, GO:0005777=IDA} cellular nitrogen compound metabolic process, fatty acid alpha-oxidation, glycolate catabolic process, glyoxylate metabolic process, response to oxidative stress, small molecule metabolic process peroxisomal matrix, peroxisome (S)-2-hydroxy-acid oxidase activity, FMN binding, glycolate oxidase activity, glyoxylate oxidase activity, long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity, medium-chain-(S)-2-hydroxy-acid oxidase activity, receptor binding, very-long-chain-(S)-2-hydroxy-acid oxidase activity Human HAO2 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0018924=GO_REF:0000019, GO:0019395=PMID:10777549, GO:0052852=GO_REF:0000003, GO:0052853=PMID:10777549, GO:0010181=GO_REF:0000019, GO:0003973=PMID:10777549, GO:0005102=PMID:20178365, GO:0016491=GO_REF:0000002, GO:0051260=GO_REF:0000019, GO:0052854=GO_REF:0000003, GO:0005777=PMID:10777549} Q9NYQ3 Hydroxyacid oxidase 2 protein 20120926 {GO:0005739=IEA, GO:0018924=IEA, GO:0019395=IDA, GO:0052852=IEA, GO:0052853=IDA, GO:0010181=IEA, GO:0003973=IDA, GO:0005102=IPI, GO:0016491=IEA, GO:0051260=IEA, GO:0052854=IEA, GO:0005777=IDA} fatty acid oxidation, mandelate metabolic process, protein homooligomerization mitochondrion, peroxisome (S)-2-hydroxy-acid oxidase activity, FMN binding, long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity, medium-chain-(S)-2-hydroxy-acid oxidase activity, oxidoreductase activity, receptor binding, very-long-chain-(S)-2-hydroxy-acid oxidase activity Human HAP1 PINC UniProtKB {GO:0005515=PMID:20515468, GO:0008104=PMID:18922795, GO:0007420=PMID:7477378, GO:0047496=GO_REF:0000019, GO:0007268=PMID:9361024, GO:0016023=GO_REF:0000019, GO:0015629=PMID:9361024, GO:0005856=PMID:9361024} P54257 Huntingtin-associated protein 1 protein 20030904 {GO:0005515=IPI, GO:0008104=IMP, GO:0007420=NAS, GO:0047496=IEA, GO:0007268=TAS, GO:0016023=IEA, GO:0015629=TAS, GO:0005856=TAS} brain development, protein localization, synaptic transmission, vesicle transport along microtubule actin cytoskeleton, cytoplasmic membrane-bounded vesicle, cytoskeleton protein binding Human HAPLN1 UniProtKB UniProtKB {GO:0005540=GO_REF:0000037, GO:0016020=GO_REF:0000038, GO:0005578=GO_REF:0000039, GO:0007155=GO_REF:0000002} P10915 Hyaluronan and proteoglycan link protein 1 protein 20130413 {GO:0005540=IEA, GO:0016020=IEA, GO:0005578=IEA, GO:0007155=IEA} cell adhesion membrane, proteinaceous extracellular matrix hyaluronic acid binding Human UniProtKB-SubCell:SL-0111 HARS HPA UniProtKB {GO:0010467=Reactome:REACT_71, GO:0005737=GO_REF:0000052, GO:0006412=PMID:7755634, GO:0005524=GO_REF:0000029, GO:0004812=GO_REF:0000002, GO:0004821=PMID:1549469, GO:0005829=Reactome:REACT_15315, GO:0006418=Reactome:REACT_15482, GO:0006427=GO_REF:0000002} P12081 Histidine--tRNA ligase, cytoplasmic protein 20110516 {GO:0010467=TAS, GO:0005737=IDA, GO:0006412=NAS, GO:0005524=NAS, GO:0004812=IEA, GO:0004821=NAS, GO:0005829=TAS, GO:0006418=TAS, GO:0006427=IEA} gene expression, histidyl-tRNA aminoacylation, tRNA aminoacylation for protein translation, translation cytoplasm, cytosol ATP binding, aminoacyl-tRNA ligase activity, histidine-tRNA ligase activity Human HARS2 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0005737=GO_REF:0000029, GO:0005759=Reactome:REACT_15376, GO:0006412=PMID:7755634, GO:0005524=GO_REF:0000029, GO:0004821=PMID:7755634, GO:0004812=GO_REF:0000002, GO:0006427=GO_REF:0000002, GO:0006418=Reactome:REACT_15482} P49590 Probable histidine--tRNA ligase, mitochondrial protein 20130301 {GO:0010467=TAS, GO:0005737=NAS, GO:0005759=TAS, GO:0006412=NAS, GO:0005524=NAS, GO:0004821=NAS, GO:0004812=IEA, GO:0006427=IEA, GO:0006418=TAS} gene expression, histidyl-tRNA aminoacylation, tRNA aminoacylation for protein translation, translation cytoplasm, mitochondrial matrix ATP binding, aminoacyl-tRNA ligase activity, histidine-tRNA ligase activity Human HAS1 Reactome UniProtKB {GO:0005886=Reactome:REACT_121109, GO:0010764=PMID:19577615, GO:0016758=GO_REF:0000002, GO:0005975=Reactome:REACT_474, GO:0005887=PMID:9169154, GO:0030213=Reactome:REACT_121301, GO:0030212=Reactome:REACT_121083, GO:0050501=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0007155=PMID:8798544, GO:0030203=Reactome:REACT_121315, GO:0006024=PMID:8798544} Q92839 Hyaluronan synthase 1 protein 20130301 {GO:0005886=TAS, GO:0010764=IMP, GO:0016758=IEA, GO:0005975=TAS, GO:0005887=TAS, GO:0030213=TAS, GO:0030212=TAS, GO:0050501=IEA, GO:0044281=TAS, GO:0007155=TAS, GO:0030203=TAS, GO:0006024=TAS} carbohydrate metabolic process, cell adhesion, glycosaminoglycan biosynthetic process, glycosaminoglycan metabolic process, hyaluronan biosynthetic process, hyaluronan metabolic process, negative regulation of fibroblast migration, small molecule metabolic process integral to plasma membrane, plasma membrane hyaluronan synthase activity, transferase activity, transferring hexosyl groups Human HAS2 BHF-UCL UniProtKB {GO:0008284=PMID:22016393, GO:0030335=PMID:22016393, GO:0005887=PMID:20522558, GO:0001822=GO_REF:0000024, GO:0071356=PMID:20522558, GO:0071347=PMID:20522558, GO:0030213=PMID:22016393, GO:0050501=PMID:22016393, GO:0070295=GO_REF:0000024, GO:0035810=GO_REF:0000024, GO:1900625=PMID:20522558, GO:0071498=PMID:21551265} Q92819 Hyaluronan synthase 2 protein 20120521 {GO:0008284=IMP, GO:0030335=IMP, GO:0005887=IDA, GO:0001822=ISS, GO:0071356=IEP, GO:0071347=IEP, GO:0030213=IMP, GO:0050501=IMP, GO:0070295=ISS, GO:0035810=ISS, GO:1900625=IMP, GO:0071498=IEP} cellular response to fluid shear stress, cellular response to interleukin-1, cellular response to tumor necrosis factor, hyaluronan biosynthetic process, kidney development, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of monocyte aggregation, positive regulation of urine volume, renal water absorption integral to plasma membrane hyaluronan synthase activity Human HAS3 Reactome UniProtKB {GO:1900106=PMID:16900089, GO:0005886=Reactome:REACT_121109, GO:0005975=Reactome:REACT_474, GO:0005887=PMID:9169154, GO:0030213=Reactome:REACT_121301, GO:0030212=Reactome:REACT_121083, GO:0036117=PMID:16900089, GO:0050501=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0016021=PMID:9083017, GO:0030203=Reactome:REACT_121315} O00219 Hyaluronan synthase 3 protein 20130301 {GO:1900106=IDA, GO:0005886=TAS, GO:0005975=TAS, GO:0005887=TAS, GO:0030213=TAS, GO:0030212=TAS, GO:0036117=IDA, GO:0050501=IEA, GO:0044281=TAS, GO:0016021=TAS, GO:0030203=TAS} carbohydrate metabolic process, glycosaminoglycan metabolic process, hyaluronan biosynthetic process, hyaluronan metabolic process, positive regulation of hyaluranon cable assembly, small molecule metabolic process hyaluranon cable, integral to membrane, integral to plasma membrane, plasma membrane hyaluronan synthase activity Human HAT1 HPA UniProtKB {GO:0005515=PMID:22190034, GO:0005737=GO_REF:0000039, GO:0006348=GO_REF:0000002, GO:0007584=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0006323=PMID:9427644, GO:0005654=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0006475=PMID:9427644, GO:0016363=GO_REF:0000039, GO:0004402=GO_REF:0000003, GO:0043231=GO_REF:0000052} O14929 Histone acetyltransferase type B catalytic subunit protein 20110516 {GO:0005515=IPI, GO:0005737=IEA, GO:0006348=IEA, GO:0007584=IEA, GO:0005730=IDA, GO:0006323=TAS, GO:0005654=IEA, GO:0005634=IDA, GO:0006475=TAS, GO:0016363=IEA, GO:0004402=IEA, GO:0043231=IDA} DNA packaging, chromatin silencing at telomere, internal protein amino acid acetylation, response to nutrient cytoplasm, intracellular membrane-bounded organelle, nuclear matrix, nucleolus, nucleoplasm, nucleus histone acetyltransferase activity, protein binding Human HAUS1 HPA UniProtKB {GO:0051297=PMID:19427217, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0005813=PMID:21399614, GO:0000922=GO_REF:0000039, GO:0007067=GO_REF:0000037, GO:0005874=GO_REF:0000037, GO:0070652=PMID:19369198, GO:0051225=PMID:19369198, GO:0051301=GO_REF:0000037} Q96CS2 HAUS augmin-like complex subunit 1 protein 20111111 {GO:0051297=IMP, GO:0003674=ND, GO:0005737=IDA, GO:0005813=IDA, GO:0000922=IEA, GO:0007067=IEA, GO:0005874=IEA, GO:0070652=IDA, GO:0051225=IMP, GO:0051301=IEA} cell division, centrosome organization, mitosis, spindle assembly HAUS complex, centrosome, cytoplasm, microtubule, spindle pole molecular_function Human HAUS2 HPA UniProtKB {GO:0005813=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0005874=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005819=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0051225=PMID:19427217, GO:0005829=Reactome:REACT_15470, GO:0051297=PMID:19427217, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0007067=GO_REF:0000037, GO:0000086=Reactome:REACT_2203, GO:0070652=PMID:19369198, GO:0000278=Reactome:REACT_152, GO:0051301=GO_REF:0000037} Q9NVX0 HAUS augmin-like complex subunit 2 protein 20110516 {GO:0005813=IDA, GO:0005794=IDA, GO:0005874=IEA, GO:0005730=IDA, GO:0005819=IEA, GO:0005634=IDA, GO:0051225=IMP, GO:0005829=TAS, GO:0051297=IMP, GO:0003674=ND, GO:0005737=IDA, GO:0007067=IEA, GO:0000086=TAS, GO:0070652=IDA, GO:0000278=TAS, GO:0051301=IEA} G2/M transition of mitotic cell cycle, cell division, centrosome organization, mitosis, mitotic cell cycle, spindle assembly Golgi apparatus, HAUS complex, centrosome, cytoplasm, cytosol, microtubule, nucleolus, nucleus, spindle molecular_function Human HAUS3 UniProtKB UniProtKB {GO:0051297=PMID:19427217, GO:0003674=GO_REF:0000015, GO:0005813=PMID:21399614, GO:0007067=GO_REF:0000037, GO:0005737=GO_REF:0000037, GO:0005874=GO_REF:0000037, GO:0005819=GO_REF:0000039, GO:0070652=PMID:19369198, GO:0051225=PMID:19427217, GO:0051301=GO_REF:0000037} Q68CZ6 HAUS augmin-like complex subunit 3 protein 20110517 {GO:0051297=IMP, GO:0003674=ND, GO:0005813=IDA, GO:0007067=IEA, GO:0005737=IEA, GO:0005874=IEA, GO:0005819=IEA, GO:0070652=IDA, GO:0051225=IMP, GO:0051301=IEA} cell division, centrosome organization, mitosis, spindle assembly HAUS complex, centrosome, cytoplasm, microtubule, spindle molecular_function Human HAUS4 UniProtKB UniProtKB {GO:0051297=PMID:19427217, GO:0003674=GO_REF:0000015, GO:0005813=PMID:21399614, GO:0007067=GO_REF:0000037, GO:0005737=GO_REF:0000037, GO:0005874=GO_REF:0000037, GO:0005819=GO_REF:0000039, GO:0070652=PMID:19369198, GO:0051225=PMID:19427217, GO:0051301=GO_REF:0000037} Q9H6D7 HAUS augmin-like complex subunit 4 protein 20110517 {GO:0051297=IMP, GO:0003674=ND, GO:0005813=IDA, GO:0007067=IEA, GO:0005737=IEA, GO:0005874=IEA, GO:0005819=IEA, GO:0070652=IDA, GO:0051225=IMP, GO:0051301=IEA} cell division, centrosome organization, mitosis, spindle assembly HAUS complex, centrosome, cytoplasm, microtubule, spindle molecular_function Human HAUS5 UniProtKB UniProtKB {GO:0051297=PMID:19427217, GO:0003674=GO_REF:0000015, GO:0005813=PMID:21399614, GO:0007067=GO_REF:0000037, GO:0005737=GO_REF:0000037, GO:0005874=GO_REF:0000037, GO:0005819=GO_REF:0000039, GO:0070652=PMID:19369198, GO:0051225=PMID:19427217, GO:0051301=GO_REF:0000037} O94927 HAUS augmin-like complex subunit 5 protein 20110517 {GO:0051297=IMP, GO:0003674=ND, GO:0005813=IDA, GO:0007067=IEA, GO:0005737=IEA, GO:0005874=IEA, GO:0005819=IEA, GO:0070652=IDA, GO:0051225=IMP, GO:0051301=IEA} cell division, centrosome organization, mitosis, spindle assembly HAUS complex, centrosome, cytoplasm, microtubule, spindle molecular_function Human HAUS6 HPA UniProtKB {GO:0051297=PMID:19427217, GO:0003674=GO_REF:0000015, GO:0007067=GO_REF:0000037, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0005874=GO_REF:0000037, GO:0005819=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0070652=PMID:19369198, GO:0005634=GO_REF:0000052, GO:0051225=PMID:19427217, GO:0051301=GO_REF:0000037} Q7Z4H7 HAUS augmin-like complex subunit 6 protein 20101115 {GO:0051297=IMP, GO:0003674=ND, GO:0007067=IEA, GO:0005813=IDA, GO:0005737=IDA, GO:0005874=IEA, GO:0005819=IEA, GO:0005730=IDA, GO:0070652=IDA, GO:0005634=IDA, GO:0051225=IMP, GO:0051301=IEA} cell division, centrosome organization, mitosis, spindle assembly HAUS complex, centrosome, cytoplasm, microtubule, nucleolus, nucleus, spindle molecular_function Human HAUS7 HPA UniProtKB {GO:0051297=PMID:19427217, GO:0007067=GO_REF:0000037, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005874=GO_REF:0000037, GO:0005819=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0070652=PMID:19369198, GO:0031996=PMID:11163772, GO:0051225=PMID:19427217, GO:0051301=GO_REF:0000037} Q99871 HAUS augmin-like complex subunit 7 protein 20101115 {GO:0051297=IMP, GO:0007067=IEA, GO:0005813=IDA, GO:0005737=IDA, GO:0005886=IDA, GO:0005874=IEA, GO:0005819=IEA, GO:0005730=IDA, GO:0070652=IDA, GO:0031996=IPI, GO:0051225=IMP, GO:0051301=IEA} cell division, centrosome organization, mitosis, spindle assembly HAUS complex, centrosome, cytoplasm, microtubule, nucleolus, plasma membrane, spindle thioesterase binding Human HAUS8 UniProtKB UniProtKB {GO:0051297=PMID:19427217, GO:0003674=GO_REF:0000015, GO:0005813=PMID:21399614, GO:0005737=GO_REF:0000039, GO:0000922=GO_REF:0000039, GO:0007067=GO_REF:0000037, GO:0005874=GO_REF:0000037, GO:0070652=PMID:19369198, GO:0051225=PMID:19427217, GO:0051301=GO_REF:0000037} Q9BT25 HAUS augmin-like complex subunit 8 protein 20110517 {GO:0051297=IMP, GO:0003674=ND, GO:0005813=IDA, GO:0005737=IEA, GO:0000922=IEA, GO:0007067=IEA, GO:0005874=IEA, GO:0070652=IDA, GO:0051225=IMP, GO:0051301=IEA} cell division, centrosome organization, mitosis, spindle assembly HAUS complex, centrosome, cytoplasm, microtubule, spindle pole molecular_function Human HAVCR1 UniProtKB UniProtKB {GO:0019048=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q96D42 Hepatitis A virus cellular receptor 1 protein 20130413 {GO:0019048=IEA, GO:0016021=IEA} virus-host interaction integral to membrane Human UniProtKB-KW:KW-0945 HAVCR2 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8TDQ0 Hepatitis A virus cellular receptor 2 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 HAX1 BHF-UCL UniProtKB {GO:0005515=PMID:21217774, GO:0005667=PMID:23001182, GO:0051897=PMID:23001182, GO:0031965=GO_REF:0000039, GO:0005783=GO_REF:0000024, GO:2000251=PMID:23001182, GO:0050731=PMID:23001182, GO:0014068=PMID:23001182, GO:0005635=PMID:9058808, GO:0015629=GO_REF:0000024, GO:0030027=GO_REF:0000024, GO:0005739=PMID:9058808, GO:0019966=PMID:11554782, GO:0033138=PMID:23001182, GO:0030833=PMID:23001182, GO:0016529=GO_REF:0000039, GO:0047485=PMID:11554782, GO:0071345=PMID:23001182, GO:0030854=PMID:23001182, GO:0045944=PMID:23001182, GO:0016023=GO_REF:0000039} O00165 HCLS1-associated protein X-1 protein 20121119 {GO:0005515=IPI, GO:0005667=IDA, GO:0051897=IMP, GO:0031965=IEA, GO:0005783=ISS, GO:2000251=IMP, GO:0050731=IMP, GO:0014068=IMP, GO:0005635=TAS, GO:0015629=ISS, GO:0030027=ISS, GO:0005739=IDA, GO:0019966=IDA, GO:0033138=IMP, GO:0030833=IMP, GO:0016529=IEA, GO:0047485=IDA, GO:0071345=IMP, GO:0030854=IMP, GO:0045944=IMP, GO:0016023=IEA} cellular response to cytokine stimulus, positive regulation of actin cytoskeleton reorganization, positive regulation of granulocyte differentiation, positive regulation of peptidyl-serine phosphorylation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of protein kinase B signaling cascade, positive regulation of transcription from RNA polymerase II promoter, regulation of actin filament polymerization actin cytoskeleton, cytoplasmic membrane-bounded vesicle, endoplasmic reticulum, lamellipodium, mitochondrion, nuclear envelope, nuclear membrane, sarcoplasmic reticulum, transcription factor complex interleukin-1 binding, protein N-terminus binding, protein binding Human HBA1 BHF-UCL UniProtKB {GO:0005515=PMID:16169070, GO:0042542=PMID:19740759, GO:0005506=GO_REF:0000002, GO:0005833=PMID:19740759, GO:0005576=Reactome:REACT_160297, GO:0044281=Reactome:REACT_111217, GO:0051291=PMID:19740759, GO:0015671=PMID:7518430, GO:0005829=Reactome:REACT_121267, GO:0031838=PMID:19740759, GO:0004601=PMID:19740759, GO:0019825=GO_REF:0000002, GO:0022627=PMID:8706699, GO:0071682=Reactome:REACT_160193, GO:0005344=GO_REF:0000037, GO:0015701=Reactome:REACT_121380, GO:0042744=PMID:19740759, GO:0010942=PMID:19740759, GO:0031720=PMID:19740759, GO:0020037=GO_REF:0000002} P69905 Hemoglobin subunit alpha protein 20110216 {GO:0005515=IPI, GO:0042542=IDA, GO:0005506=IEA, GO:0005833=IDA, GO:0005576=TAS, GO:0044281=TAS, GO:0051291=IDA, GO:0015671=TAS, GO:0005829=TAS, GO:0031838=IDA, GO:0004601=IDA, GO:0019825=IEA, GO:0022627=IDA, GO:0071682=TAS, GO:0005344=IEA, GO:0015701=TAS, GO:0042744=IDA, GO:0010942=IDA, GO:0031720=IDA, GO:0020037=IEA} bicarbonate transport, hydrogen peroxide catabolic process, oxygen transport, positive regulation of cell death, protein heterooligomerization, response to hydrogen peroxide, small molecule metabolic process cytosol, cytosolic small ribosomal subunit, endocytic vesicle lumen, extracellular region, haptoglobin-hemoglobin complex, hemoglobin complex haptoglobin binding, heme binding, iron ion binding, oxygen binding, oxygen transporter activity, peroxidase activity, protein binding Human HBA2 UniProtKB UniProtKB {GO:0019825=GO_REF:0000002, GO:0005833=GO_REF:0000002, GO:0005506=GO_REF:0000002, GO:0005344=GO_REF:0000038, GO:0020037=GO_REF:0000002} G3V1N2 HCG1745306, isoform CRA_a protein 20130413 {GO:0019825=IEA, GO:0005833=IEA, GO:0005506=IEA, GO:0005344=IEA, GO:0020037=IEA} hemoglobin complex heme binding, iron ion binding, oxygen binding, oxygen transporter activity Human UniProtKB-KW:KW-0561 HBB BHF-UCL UniProtKB {GO:0005515=PMID:16169070, GO:0042542=PMID:19740759, GO:0044281=Reactome:REACT_111217, GO:0051291=PMID:19740759, GO:0070293=PMID:18465053, GO:0045429=PMID:7965120, GO:0005829=Reactome:REACT_121267, GO:0030492=PMID:1512262, GO:0031838=PMID:19740759, GO:0050880=GO_REF:0000037, GO:0004601=PMID:19740759, GO:0030185=PMID:8292032, GO:0071682=Reactome:REACT_160193, GO:0042744=PMID:19740759, GO:0010942=PMID:19740759, GO:0031720=PMID:19740759, GO:0005833=PMID:19740759, GO:0005506=GO_REF:0000002, GO:0005576=Reactome:REACT_160297, GO:0015671=PMID:11747442, GO:0019825=PMID:11747442, GO:0007596=Reactome:REACT_604, GO:0008217=GO_REF:0000037, GO:0005344=PMID:11747442, GO:0015701=Reactome:REACT_121380, GO:0020037=GO_REF:0000002} P68871 Hemoglobin subunit beta protein 20110216 {GO:0005515=IPI, GO:0042542=IDA, GO:0044281=TAS, GO:0051291=IDA, GO:0070293=IMP, GO:0045429=NAS, GO:0005829=TAS, GO:0030492=IDA, GO:0031838=IDA, GO:0050880=IEA, GO:0004601=IDA, GO:0030185=NAS, GO:0071682=TAS, GO:0042744=IDA, GO:0010942=IDA, GO:0031720=IDA, GO:0005833=IDA, GO:0005506=IEA, GO:0005576=TAS, GO:0015671=NAS, GO:0019825=IDA, GO:0007596=TAS, GO:0008217=IEA, GO:0005344=NAS, GO:0015701=TAS, GO:0020037=IEA} bicarbonate transport, blood coagulation, hydrogen peroxide catabolic process, nitric oxide transport, oxygen transport, positive regulation of cell death, positive regulation of nitric oxide biosynthetic process, protein heterooligomerization, regulation of blood pressure, regulation of blood vessel size, renal absorption, response to hydrogen peroxide, small molecule metabolic process cytosol, endocytic vesicle lumen, extracellular region, haptoglobin-hemoglobin complex, hemoglobin complex haptoglobin binding, heme binding, hemoglobin binding, iron ion binding, oxygen binding, oxygen transporter activity, peroxidase activity, protein binding Human HBD Reactome UniProtKB {GO:0005833=GO_REF:0000002, GO:0019825=GO_REF:0000002, GO:0005506=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0005344=GO_REF:0000037, GO:0005829=Reactome:REACT_25336, GO:0020037=GO_REF:0000002} P02042 Hemoglobin subunit delta protein 20130301 {GO:0005833=IEA, GO:0019825=IEA, GO:0005506=IEA, GO:0007596=TAS, GO:0005344=IEA, GO:0005829=TAS, GO:0020037=IEA} blood coagulation cytosol, hemoglobin complex heme binding, iron ion binding, oxygen binding, oxygen transporter activity Human HBE1 Reactome UniProtKB {GO:0019825=GO_REF:0000002, GO:0005833=GO_REF:0000002, GO:0005506=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0005344=GO_REF:0000037, GO:0000122=GO_REF:0000019, GO:0005829=Reactome:REACT_25336, GO:0020037=GO_REF:0000002} P02100 Hemoglobin subunit epsilon protein 20130301 {GO:0019825=IEA, GO:0005833=IEA, GO:0005506=IEA, GO:0007596=TAS, GO:0005344=IEA, GO:0000122=IEA, GO:0005829=TAS, GO:0020037=IEA} blood coagulation, negative regulation of transcription from RNA polymerase II promoter cytosol, hemoglobin complex heme binding, iron ion binding, oxygen binding, oxygen transporter activity Human HBEGF BHF-UCL UniProtKB {GO:0051545=GO_REF:0000019, GO:0051897=PMID:17655843, GO:0048011=Reactome:REACT_11061, GO:0005154=GO_REF:0000019, GO:0030335=PMID:17655843, GO:0035313=GO_REF:0000019, GO:0043499=PMID:12070119, GO:0051549=GO_REF:0000019, GO:0009986=PMID:12743035, GO:0030307=GO_REF:0000019, GO:0090303=PMID:17655843, GO:0048015=Reactome:REACT_12464, GO:0008016=GO_REF:0000019, GO:0005576=Reactome:REACT_147854, GO:0048661=GO_REF:0000019, GO:0005615=PMID:12743035, GO:0007165=PMID:1840698, GO:0007517=PMID:8347598, GO:0007173=PMID:17655843, GO:0008543=Reactome:REACT_9470, GO:0005887=GO_REF:0000024, GO:0045087=Reactome:REACT_6802, GO:0008083=GO_REF:0000019, GO:0008201=PMID:8300582} Q99075 Proheparin-binding EGF-like growth factor protein 20081121 {GO:0051545=IEA, GO:0051897=IMP, GO:0048011=TAS, GO:0005154=IEA, GO:0030335=IMP, GO:0035313=IEA, GO:0043499=IDA, GO:0051549=IEA, GO:0009986=IDA, GO:0030307=IEA, GO:0090303=IMP, GO:0048015=TAS, GO:0008016=IEA, GO:0005576=TAS, GO:0048661=IEA, GO:0005615=IDA, GO:0007165=TAS, GO:0007517=TAS, GO:0007173=IMP, GO:0008543=TAS, GO:0005887=ISS, GO:0045087=TAS, GO:0008083=IEA, GO:0008201=IMP} epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, muscle organ development, negative regulation of elastin biosynthetic process, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of cell growth, positive regulation of cell migration, positive regulation of keratinocyte migration, positive regulation of protein kinase B signaling cascade, positive regulation of smooth muscle cell proliferation, positive regulation of wound healing, regulation of heart contraction, signal transduction, wound healing, spreading of epidermal cells cell surface, extracellular region, extracellular space, integral to plasma membrane epidermal growth factor receptor binding, eukaryotic cell surface binding, growth factor activity, heparin binding Human HBG1 Reactome UniProtKB {GO:0019825=GO_REF:0000002, GO:0005833=GO_REF:0000002, GO:0005506=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0005344=GO_REF:0000037, GO:0005829=Reactome:REACT_25336, GO:0020037=GO_REF:0000002} P69891 Hemoglobin subunit gamma-1 protein 20130301 {GO:0019825=IEA, GO:0005833=IEA, GO:0005506=IEA, GO:0007596=TAS, GO:0005344=IEA, GO:0005829=TAS, GO:0020037=IEA} blood coagulation cytosol, hemoglobin complex heme binding, iron ion binding, oxygen binding, oxygen transporter activity Human HBG2 Reactome UniProtKB {GO:0019825=GO_REF:0000002, GO:0005833=GO_REF:0000002, GO:0005506=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0005344=GO_REF:0000037, GO:0005829=Reactome:REACT_25336, GO:0020037=GO_REF:0000002} P69892 Hemoglobin subunit gamma-2 protein 20130301 {GO:0019825=IEA, GO:0005833=IEA, GO:0005506=IEA, GO:0007596=TAS, GO:0005344=IEA, GO:0005829=TAS, GO:0020037=IEA} blood coagulation cytosol, hemoglobin complex heme binding, iron ion binding, oxygen binding, oxygen transporter activity Human HBP1 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0003723=GO_REF:0000002, GO:0043268=GO_REF:0000019, GO:0007050=PMID:9030690, GO:0005634=GO_REF:0000039, GO:0016055=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O60381 HMG box-containing protein 1 protein 20060210 {GO:0006355=IEA, GO:0003723=IEA, GO:0043268=IEA, GO:0007050=NAS, GO:0005634=IEA, GO:0016055=IEA, GO:0003677=IEA, GO:0006351=IEA} Wnt receptor signaling pathway, cell cycle arrest, positive regulation of potassium ion transport, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, RNA binding Human HBS1L PINC UniProtKB {GO:0007165=PMID:9872408, GO:0003924=GO_REF:0000002, GO:0003746=GO_REF:0000037, GO:0005525=GO_REF:0000037, GO:0006412=PMID:9872408} Q9Y450 HBS1-like protein protein 20030904 {GO:0007165=TAS, GO:0003924=IEA, GO:0003746=IEA, GO:0005525=IEA, GO:0006412=TAS} signal transduction, translation GTP binding, GTPase activity, translation elongation factor activity Human HBZ ENSEMBL UniProtKB {GO:0043249=GO_REF:0000019, GO:0019825=GO_REF:0000002, GO:0005833=GO_REF:0000002, GO:0005506=GO_REF:0000002, GO:0005344=GO_REF:0000037, GO:0000122=GO_REF:0000019, GO:0020037=GO_REF:0000002} P02008 Hemoglobin subunit zeta protein 20130413 {GO:0043249=IEA, GO:0019825=IEA, GO:0005833=IEA, GO:0005506=IEA, GO:0005344=IEA, GO:0000122=IEA, GO:0020037=IEA} erythrocyte maturation, negative regulation of transcription from RNA polymerase II promoter hemoglobin complex heme binding, iron ion binding, oxygen binding, oxygen transporter activity Human Ensembl:ENSMUSP00000020531 HCCS HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005743=GO_REF:0000039, GO:0004408=GO_REF:0000003, GO:0009887=PMID:8661044, GO:0046872=GO_REF:0000037, GO:0055114=PMID:8661044} P53701 Cytochrome c-type heme lyase protein 20080205 {GO:0005739=IDA, GO:0005743=IEA, GO:0004408=IEA, GO:0009887=TAS, GO:0046872=IEA, GO:0055114=TAS} organ morphogenesis, oxidation-reduction process mitochondrial inner membrane, mitochondrion holocytochrome-c synthase activity, metal ion binding Human HCFC1 HPA UniProtKB {GO:0005515=PMID:21909281, GO:0003700=PMID:8392914, GO:0006366=PMID:8392914, GO:0005634=GO_REF:0000052, GO:0070461=PMID:18838386, GO:0042802=PMID:12670868, GO:0005739=GO_REF:0000052, GO:0005737=PMID:20091349, GO:0048188=PMID:17998332, GO:0071339=PMID:15960975, GO:0043996=PMID:20018852, GO:0000123=PMID:20018852, GO:0043995=PMID:20018852, GO:0043025=PMID:20091349, GO:0006355=PMID:12670868, GO:0003713=PMID:10675337, GO:0005730=GO_REF:0000052, GO:0050821=PMID:21285374, GO:0000122=GO_REF:0000024, GO:0045787=PMID:10623756, GO:0010628=PMID:21285374, GO:0043981=PMID:20018852, GO:0007049=GO_REF:0000037, GO:0043982=PMID:20018852, GO:0019046=PMID:10675337, GO:0070688=PMID:19377461, GO:0043984=PMID:20018852, GO:0003682=PMID:21285374, GO:0043254=PMID:10675337, GO:0005671=PMID:18838386, GO:0046972=PMID:20018852} P51610 Host cell factor 1 protein 20100326 {GO:0005515=IPI, GO:0003700=NAS, GO:0006366=TAS, GO:0005634=IDA, GO:0070461=IDA, GO:0042802=IPI, GO:0005739=IDA, GO:0005737=IDA, GO:0048188=IDA, GO:0071339=IDA, GO:0043996=IDA, GO:0000123=IDA, GO:0043995=IDA, GO:0043025=IDA, GO:0006355=IDA, GO:0003713=IMP, GO:0005730=IDA, GO:0050821=IDA, GO:0000122=ISS, GO:0045787=TAS, GO:0010628=IDA, GO:0043981=IDA, GO:0007049=IEA, GO:0043982=IDA, GO:0019046=NAS, GO:0070688=IDA, GO:0043984=IDA, GO:0003682=IDA, GO:0043254=IDA, GO:0005671=IDA, GO:0046972=IDA} cell cycle, histone H4-K16 acetylation, histone H4-K5 acetylation, histone H4-K8 acetylation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of cell cycle, positive regulation of gene expression, protein stabilization, regulation of protein complex assembly, regulation of transcription, DNA-dependent, release from viral latency, transcription from RNA polymerase II promoter Ada2/Gcn5/Ada3 transcription activator complex, MLL1 complex, MLL5-L complex, SAGA-type complex, Set1C/COMPASS complex, cytoplasm, histone acetyltransferase complex, mitochondrion, neuronal cell body, nucleolus, nucleus chromatin binding, histone acetyltransferase activity (H4-K16 specific), histone acetyltransferase activity (H4-K5 specific), histone acetyltransferase activity (H4-K8 specific), identical protein binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity Human HCFC1R1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039} Q9NWW0 Host cell factor C1 regulator 1 protein 20130413 {GO:0005737=IEA, GO:0005634=IEA} cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 HCFC2 PINC UniProtKB {GO:0005737=PMID:10196288, GO:0006357=PMID:10196288, GO:0003713=PMID:10196288, GO:0016032=PMID:10196288, GO:0005634=GO_REF:0000039, GO:0000122=GO_REF:0000024} Q9Y5Z7 Host cell factor 2 protein 20030904 {GO:0005737=IDA, GO:0006357=TAS, GO:0003713=TAS, GO:0016032=TAS, GO:0005634=IEA, GO:0000122=ISS} negative regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, viral reproduction cytoplasm, nucleus transcription coactivator activity Human HCK IntAct UniProtKB {GO:0005515=PMID:19234535, GO:0030133=GO_REF:0000039, GO:0006909=GO_REF:0000019, GO:0008284=PMID:10092522, GO:0071801=PMID:15998323, GO:0050830=GO_REF:0000019, GO:0005884=PMID:15998323, GO:0008360=PMID:10092522, GO:0019221=PMID:18538446, GO:2000251=PMID:11904303, GO:0005634=GO_REF:0000039, GO:0042995=GO_REF:0000037, GO:0005764=PMID:15998323, GO:0005829=Reactome:REACT_160304, GO:0050764=PMID:11904303, GO:0051090=PMID:17535448, GO:0002758=PMID:18538446, GO:0046777=PMID:10092522, GO:0006954=GO_REF:0000037, GO:0030838=PMID:18538446, GO:0016032=Reactome:REACT_6185, GO:0007155=PMID:18538446, GO:0031663=PMID:18538446, GO:0060333=PMID:18538446, GO:0043066=PMID:17535448, GO:0005794=GO_REF:0000039, GO:0002522=PMID:18538446, GO:0050727=PMID:18538446, GO:0045728=PMID:18538446, GO:0018108=PMID:10092522, GO:0043299=PMID:18538446, GO:0005524=GO_REF:0000037, GO:0050690=Reactome:REACT_11068, GO:0031234=PMID:11904303, GO:0007229=PMID:18538446, GO:0045087=Reactome:REACT_6802, GO:0005901=PMID:7791757, GO:0019048=GO_REF:0000037, GO:0007498=PMID:3453117, GO:0006468=PMID:3496523, GO:0004713=PMID:10092522, GO:0038096=Reactome:REACT_160123, GO:0004715=GO_REF:0000003, GO:0005925=PMID:11904303} P08631 Tyrosine-protein kinase HCK protein 20130415 {GO:0005515=IPI, GO:0030133=IEA, GO:0006909=IEA, GO:0008284=IMP, GO:0071801=IDA, GO:0050830=IEA, GO:0005884=IDA, GO:0008360=IMP, GO:0019221=TAS, GO:2000251=IMP, GO:0005634=IEA, GO:0042995=IEA, GO:0005764=IDA, GO:0005829=TAS, GO:0050764=IMP, GO:0051090=IMP, GO:0002758=TAS, GO:0046777=IMP, GO:0006954=IEA, GO:0030838=TAS, GO:0016032=TAS, GO:0007155=TAS, GO:0031663=TAS, GO:0060333=TAS, GO:0043066=IMP, GO:0005794=IEA, GO:0002522=TAS, GO:0050727=TAS, GO:0045728=TAS, GO:0018108=IMP, GO:0043299=TAS, GO:0005524=IEA, GO:0050690=TAS, GO:0031234=IMP, GO:0007229=TAS, GO:0045087=TAS, GO:0005901=IDA, GO:0019048=IEA, GO:0007498=TAS, GO:0006468=TAS, GO:0004713=IMP, GO:0038096=TAS, GO:0004715=IEA, GO:0005925=IMP} Fc-gamma receptor signaling pathway involved in phagocytosis, cell adhesion, cytokine-mediated signaling pathway, defense response to Gram-positive bacterium, inflammatory response, innate immune response, innate immune response-activating signal transduction, integrin-mediated signaling pathway, interferon-gamma-mediated signaling pathway, leukocyte degranulation, leukocyte migration involved in immune response, lipopolysaccharide-mediated signaling pathway, mesoderm development, negative regulation of apoptotic process, peptidyl-tyrosine phosphorylation, phagocytosis, positive regulation of actin cytoskeleton reorganization, positive regulation of actin filament polymerization, positive regulation of cell proliferation, protein autophosphorylation, protein phosphorylation, regulation of cell shape, regulation of defense response to virus by virus, regulation of inflammatory response, regulation of phagocytosis, regulation of podosome assembly, regulation of sequence-specific DNA binding transcription factor activity, respiratory burst after phagocytosis, viral reproduction, virus-host interaction Golgi apparatus, actin filament, caveola, cell projection, cytosol, extrinsic to internal side of plasma membrane, focal adhesion, lysosome, nucleus, transport vesicle ATP binding, non-membrane spanning protein tyrosine kinase activity, protein binding, protein tyrosine kinase activity Human UniProtKB:P42768 HCLS1 BHF-UCL UniProtKB {GO:0005515=PMID:21398607, GO:0051897=PMID:23001182, GO:0008284=GO_REF:0000024, GO:0017124=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0050731=PMID:23001182, GO:2000251=PMID:23001182, GO:0005634=PMID:23001182, GO:0042993=PMID:23001182, GO:0032403=GO_REF:0000019, GO:0035556=PMID:8978766, GO:0005739=GO_REF:0000039, GO:0005737=PMID:23001182, GO:0033138=PMID:23001182, GO:0030833=PMID:23001182, GO:0030854=PMID:23001182, GO:0045944=PMID:23001182, GO:0001085=PMID:23001182, GO:0009725=GO_REF:0000024, GO:0005667=PMID:23001182, GO:0006355=PMID:2587259, GO:0042531=GO_REF:0000024, GO:0019901=PMID:23001182, GO:0014068=PMID:23001182, GO:2000107=PMID:23001182, GO:0071345=PMID:23001182, GO:0030218=GO_REF:0000024} P14317 Hematopoietic lineage cell-specific protein protein 20121119 {GO:0005515=IPI, GO:0051897=IMP, GO:0008284=ISS, GO:0017124=IEA, GO:0005886=IDA, GO:0050731=IMP, GO:2000251=IC, GO:0005634=IDA, GO:0042993=IMP, GO:0032403=IEA, GO:0035556=TAS, GO:0005739=IEA, GO:0005737=IDA, GO:0033138=IMP, GO:0030833=IMP, GO:0030854=IMP, GO:0045944=IMP, GO:0001085=IPI, GO:0009725=ISS, GO:0005667=IDA, GO:0006355=TAS, GO:0042531=ISS, GO:0019901=IPI, GO:0014068=IMP, GO:2000107=IMP, GO:0071345=IMP, GO:0030218=ISS} cellular response to cytokine stimulus, erythrocyte differentiation, intracellular signal transduction, negative regulation of leukocyte apoptotic process, positive regulation of actin cytoskeleton reorganization, positive regulation of cell proliferation, positive regulation of granulocyte differentiation, positive regulation of peptidyl-serine phosphorylation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of protein kinase B signaling cascade, positive regulation of transcription factor import into nucleus, positive regulation of transcription from RNA polymerase II promoter, positive regulation of tyrosine phosphorylation of STAT protein, regulation of actin filament polymerization, regulation of transcription, DNA-dependent, response to hormone stimulus cytoplasm, mitochondrion, nucleus, plasma membrane, transcription factor complex RNA polymerase II transcription factor binding, SH3 domain binding, protein binding, protein complex binding, protein kinase binding Human HCN1 Reactome UniProtKB {GO:0030424=GO_REF:0000019, GO:0030552=GO_REF:0000037, GO:0005886=Reactome:REACT_75788, GO:0046549=GO_REF:0000019, GO:0005272=GO_REF:0000037, GO:0005249=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0005267=PMID:9405696, GO:0045176=GO_REF:0000019, GO:0016021=PMID:9405696, GO:0006813=PMID:9405696, GO:0030425=GO_REF:0000019} O60741 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 protein 20101019 {GO:0030424=IEA, GO:0030552=IEA, GO:0005886=TAS, GO:0046549=IEA, GO:0005272=IEA, GO:0005249=IEA, GO:0007268=TAS, GO:0005267=NAS, GO:0045176=IEA, GO:0016021=NAS, GO:0006813=NAS, GO:0030425=IEA} apical protein localization, potassium ion transport, retinal cone cell development, synaptic transmission axon, dendrite, integral to membrane, plasma membrane cAMP binding, potassium channel activity, sodium channel activity, voltage-gated potassium channel activity Human HCN2 Reactome UniProtKB {GO:0006936=PMID:10228147, GO:0005261=PMID:10228147, GO:0030552=GO_REF:0000037, GO:0005886=Reactome:REACT_75788, GO:0005272=GO_REF:0000037, GO:0008076=PMID:9630217, GO:0005249=GO_REF:0000002, GO:0042391=GO_REF:0000019, GO:0007267=PMID:9630217, GO:0007268=Reactome:REACT_13685, GO:0006812=PMID:10228147} Q9UL51 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 protein 20101019 {GO:0006936=TAS, GO:0005261=TAS, GO:0030552=IEA, GO:0005886=TAS, GO:0005272=IEA, GO:0008076=TAS, GO:0005249=IEA, GO:0042391=IEA, GO:0007267=TAS, GO:0007268=TAS, GO:0006812=TAS} cation transport, cell-cell signaling, muscle contraction, regulation of membrane potential, synaptic transmission plasma membrane, voltage-gated potassium channel complex cAMP binding, cation channel activity, sodium channel activity, voltage-gated potassium channel activity Human HCN3 Reactome UniProtKB {GO:0030552=GO_REF:0000037, GO:0005886=Reactome:REACT_75788, GO:0005272=GO_REF:0000037, GO:0005249=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0016021=GO_REF:0000037} Q9P1Z3 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 protein 20101019 {GO:0030552=IEA, GO:0005886=TAS, GO:0005272=IEA, GO:0005249=IEA, GO:0007268=TAS, GO:0016021=IEA} synaptic transmission integral to membrane, plasma membrane cAMP binding, sodium channel activity, voltage-gated potassium channel activity Human HCN4 Reactome UniProtKB {GO:0005261=PMID:10228147, GO:0005886=Reactome:REACT_75788, GO:0005272=GO_REF:0000037, GO:0008015=PMID:10228147, GO:0005222=GO_REF:0000019, GO:0008016=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0001701=GO_REF:0000019, GO:0030552=GO_REF:0000037, GO:0006936=PMID:10228147, GO:0005249=GO_REF:0000002, GO:0043195=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0006812=PMID:10228147} Q9Y3Q4 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 protein 20101019 {GO:0005261=TAS, GO:0005886=TAS, GO:0005272=IEA, GO:0008015=NAS, GO:0005222=IEA, GO:0008016=IEA, GO:0007268=TAS, GO:0001701=IEA, GO:0030552=IEA, GO:0006936=TAS, GO:0005249=IEA, GO:0043195=IEA, GO:0016021=IEA, GO:0006812=TAS} blood circulation, cation transport, in utero embryonic development, muscle contraction, regulation of heart contraction, synaptic transmission integral to membrane, plasma membrane, terminal bouton cAMP binding, cation channel activity, intracellular cAMP activated cation channel activity, sodium channel activity, voltage-gated potassium channel activity Human HCRT Reactome UniProtKB {GO:0005791=GO_REF:0000039, GO:0048471=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0051928=GO_REF:0000019, GO:0060079=GO_REF:0000019, GO:0043267=GO_REF:0000019, GO:0007268=PMID:9419374, GO:0007200=GO_REF:0000019, GO:0046928=GO_REF:0000019, GO:0005576=Reactome:REACT_22436, GO:0051970=GO_REF:0000019, GO:0051971=GO_REF:0000019, GO:0007204=GO_REF:0000019, GO:0007205=GO_REF:0000019, GO:0008021=PMID:9419374, GO:0031771=GO_REF:0000019, GO:0031772=GO_REF:0000019, GO:0007218=GO_REF:0000037, GO:0042755=GO_REF:0000019, GO:0008156=GO_REF:0000019, GO:0030141=GO_REF:0000019} O43612 Orexin protein 20090107 {GO:0005791=IEA, GO:0048471=IEA, GO:0030054=IEA, GO:0051928=IEA, GO:0060079=IEA, GO:0043267=IEA, GO:0007268=TAS, GO:0007200=IEA, GO:0046928=IEA, GO:0005576=TAS, GO:0051970=IEA, GO:0051971=IEA, GO:0007204=IEA, GO:0007205=IEA, GO:0008021=TAS, GO:0031771=IEA, GO:0031772=IEA, GO:0007218=IEA, GO:0042755=IEA, GO:0008156=IEA, GO:0030141=IEA} eating behavior, elevation of cytosolic calcium ion concentration, negative regulation of DNA replication, negative regulation of potassium ion transport, negative regulation of transmission of nerve impulse, neuropeptide signaling pathway, phospholipase C-activating G-protein coupled receptor signaling pathway, positive regulation of calcium ion transport, positive regulation of transmission of nerve impulse, protein kinase C-activating G-protein coupled receptor signaling pathway, regulation of excitatory postsynaptic membrane potential, regulation of neurotransmitter secretion, synaptic transmission cell junction, extracellular region, perinuclear region of cytoplasm, rough endoplasmic reticulum, secretory granule, synaptic vesicle type 1 hypocretin receptor binding, type 2 hypocretin receptor binding Human HCRTR1 Reactome UniProtKB {GO:0016499=GO_REF:0000002, GO:0007631=GO_REF:0000002, GO:0005886=Reactome:REACT_22436, GO:0005887=PMID:9491897, GO:0004930=PMID:9491897, GO:0007218=GO_REF:0000019, GO:0007268=PMID:9491897, GO:0016021=GO_REF:0000038, GO:0017046=GO_REF:0000019} O43613 Orexin receptor type 1 protein 20090107 {GO:0016499=IEA, GO:0007631=IEA, GO:0005886=TAS, GO:0005887=TAS, GO:0004930=TAS, GO:0007218=IEA, GO:0007268=TAS, GO:0016021=IEA, GO:0017046=IEA} feeding behavior, neuropeptide signaling pathway, synaptic transmission integral to membrane, integral to plasma membrane, plasma membrane G-protein coupled receptor activity, orexin receptor activity, peptide hormone binding Human HCRTR2 Reactome UniProtKB {GO:0016499=GO_REF:0000019, GO:0007631=GO_REF:0000019, GO:0005886=Reactome:REACT_22436, GO:0007218=PMID:9491897, GO:0005887=PMID:9491897, GO:0007268=PMID:9491897, GO:0007200=GO_REF:0000019, GO:0017046=GO_REF:0000019, GO:0008188=PMID:9491897} O43614 Orexin receptor type 2 protein 20090107 {GO:0016499=IEA, GO:0007631=IEA, GO:0005886=TAS, GO:0007218=TAS, GO:0005887=TAS, GO:0007268=TAS, GO:0007200=IEA, GO:0017046=IEA, GO:0008188=TAS} feeding behavior, neuropeptide signaling pathway, phospholipase C-activating G-protein coupled receptor signaling pathway, synaptic transmission integral to plasma membrane, plasma membrane neuropeptide receptor activity, orexin receptor activity, peptide hormone binding Human HCST Reactome UniProtKB {GO:0005515=PMID:10426994, GO:0005886=Reactome:REACT_11178, GO:0009986=PMID:10426994, GO:0050776=Reactome:REACT_11152, GO:0014068=PMID:10426994, GO:0016021=GO_REF:0000037, GO:0043548=PMID:10426994} Q9UBK5 Hematopoietic cell signal transducer protein 20070516 {GO:0005515=IPI, GO:0005886=TAS, GO:0009986=IDA, GO:0050776=TAS, GO:0014068=IDA, GO:0016021=IEA, GO:0043548=IDA} positive regulation of phosphatidylinositol 3-kinase cascade, regulation of immune response cell surface, integral to membrane, plasma membrane phosphatidylinositol 3-kinase binding, protein binding Human HDAC1 InterPro UniProtKB {GO:0005515=PMID:16964284, GO:0010467=Reactome:REACT_71, GO:0000790=PMID:22926524, GO:0003700=PMID:8646880, GO:0006367=Reactome:REACT_12627, GO:0010832=PMID:10983972, GO:0016581=PMID:17827154, GO:0007219=Reactome:REACT_118859, GO:0016580=PMID:17827154, GO:0007179=Reactome:REACT_6844, GO:0001103=PMID:22926524, GO:0001106=PMID:15919722, GO:0060766=PMID:15919722, GO:0000122=PMID:18854353, GO:0045786=Reactome:REACT_13695, GO:0033558=PMID:17172643, GO:0043922=PMID:16540471, GO:0000118=PMID:12711221, GO:0005654=PMID:22926524, GO:0061198=GO_REF:0000024, GO:0000278=Reactome:REACT_152, GO:0019899=PMID:11641274, GO:0045893=PMID:16762839, GO:0042733=GO_REF:0000024, GO:0008134=PMID:18850004, GO:0008284=PMID:18347167, GO:0042826=PMID:12590135, GO:0005634=GO_REF:0000052, GO:0046970=GO_REF:0000003, GO:0010870=PMID:18316616, GO:0005829=PMID:18326024, GO:0097372=GO_REF:0000003, GO:0005737=PMID:12711221, GO:0061029=GO_REF:0000024, GO:0045944=PMID:16762839, GO:0042475=GO_REF:0000024, GO:0006338=PMID:17827154, GO:0004407=GO_REF:0000002, GO:0033613=PMID:20590529, GO:0006476=PMID:17172643, GO:0046969=GO_REF:0000003, GO:0032041=GO_REF:0000003, GO:0070932=PMID:12590135, GO:0070933=PMID:12590135, GO:0016575=PMID:19182791, GO:0048011=Reactome:REACT_13776, GO:0043066=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0060789=GO_REF:0000024, GO:0006351=Reactome:REACT_121061, GO:0009913=GO_REF:0000024, GO:0007596=Reactome:REACT_604, GO:0019048=GO_REF:0000037, GO:0016568=PMID:12711221} Q5TEE2 Histone deacetylase 1 protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0000790=IDA, GO:0003700=TAS, GO:0006367=TAS, GO:0010832=IMP, GO:0016581=IDA, GO:0007219=TAS, GO:0016580=IDA, GO:0007179=TAS, GO:0001103=IPI, GO:0001106=IDA, GO:0060766=IDA, GO:0000122=IDA, GO:0045786=TAS, GO:0033558=IDA, GO:0043922=IMP, GO:0000118=TAS, GO:0005654=IDA, GO:0061198=ISS, GO:0000278=TAS, GO:0019899=IPI, GO:0045893=IDA, GO:0042733=ISS, GO:0008134=IPI, GO:0008284=IMP, GO:0042826=IPI, GO:0005634=IDA, GO:0046970=IEA, GO:0010870=IMP, GO:0005829=IDA, GO:0097372=IEA, GO:0005737=TAS, GO:0061029=ISS, GO:0045944=IDA, GO:0042475=ISS, GO:0006338=IC, GO:0004407=IEA, GO:0033613=IPI, GO:0006476=IDA, GO:0046969=IEA, GO:0032041=IEA, GO:0070932=IDA, GO:0070933=IDA, GO:0016575=IMP, GO:0048011=TAS, GO:0043066=ISS, GO:0005730=IDA, GO:0060789=ISS, GO:0006351=TAS, GO:0009913=ISS, GO:0007596=TAS, GO:0019048=IEA, GO:0016568=TAS} Notch signaling pathway, blood coagulation, chromatin modification, chromatin remodeling, embryonic digit morphogenesis, epidermal cell differentiation, eyelid development in camera-type eye, fungiform papilla formation, gene expression, hair follicle placode formation, histone H3 deacetylation, histone H4 deacetylation, histone deacetylation, mitotic cell cycle, negative regulation by host of viral transcription, negative regulation of androgen receptor signaling pathway, negative regulation of apoptotic process, negative regulation of cell cycle, negative regulation of myotube differentiation, negative regulation of transcription from RNA polymerase II promoter, neurotrophin TRK receptor signaling pathway, odontogenesis of dentin-containing tooth, positive regulation of cell proliferation, positive regulation of receptor biosynthetic process, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein deacetylation, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, virus-host interaction NuRD complex, Sin3 complex, cytoplasm, cytosol, histone deacetylase complex, nuclear chromatin, nucleolus, nucleoplasm, nucleus NAD-dependent histone deacetylase activity (H3-K14 specific), NAD-dependent histone deacetylase activity (H3-K18 specific), NAD-dependent histone deacetylase activity (H3-K9 specific), NAD-dependent histone deacetylase activity (H4-K16 specific), RNA polymerase II repressing transcription factor binding, RNA polymerase II transcription corepressor activity, activating transcription factor binding, enzyme binding, histone deacetylase activity, histone deacetylase binding, protein binding, protein deacetylase activity, sequence-specific DNA binding transcription factor activity, transcription factor binding Human InterPro:IPR003084 HDAC10 Reactome UniProtKB {GO:0005515=PMID:17172643, GO:0032041=GO_REF:0000003, GO:0006355=PMID:11861901, GO:0016575=PMID:11861901, GO:0042826=PMID:11861901, GO:0005634=PMID:11861901, GO:0046970=GO_REF:0000003, GO:0000122=PMID:11726666, GO:0033558=PMID:17172643, GO:0006351=GO_REF:0000037, GO:0097372=GO_REF:0000003, GO:0005737=PMID:11861901, GO:0000118=PMID:11861901, GO:0007219=Reactome:REACT_118859, GO:0016787=GO_REF:0000038, GO:0014003=GO_REF:0000019, GO:0005654=Reactome:REACT_160192, GO:0004407=PMID:11861901, GO:0019899=PMID:11861901, GO:0006476=PMID:17172643, GO:0046969=GO_REF:0000003, GO:0045892=PMID:11726666, GO:0016568=PMID:11861901} Q969S8 Histone deacetylase 10 protein 20130301 {GO:0005515=IPI, GO:0032041=IEA, GO:0006355=IDA, GO:0016575=IDA, GO:0042826=IDA, GO:0005634=IDA, GO:0046970=IEA, GO:0000122=IDA, GO:0033558=IDA, GO:0006351=IEA, GO:0097372=IEA, GO:0005737=IDA, GO:0000118=IDA, GO:0007219=TAS, GO:0016787=IEA, GO:0014003=IEA, GO:0005654=TAS, GO:0004407=IDA, GO:0019899=IPI, GO:0006476=IDA, GO:0046969=IEA, GO:0045892=IDA, GO:0016568=NAS} Notch signaling pathway, chromatin modification, histone deacetylation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, oligodendrocyte development, protein deacetylation, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, histone deacetylase complex, nucleoplasm, nucleus NAD-dependent histone deacetylase activity (H3-K14 specific), NAD-dependent histone deacetylase activity (H3-K18 specific), NAD-dependent histone deacetylase activity (H3-K9 specific), NAD-dependent histone deacetylase activity (H4-K16 specific), enzyme binding, histone deacetylase activity, histone deacetylase binding, hydrolase activity, protein binding, protein deacetylase activity Human HDAC11 LIFEdb UniProtKB {GO:0032041=GO_REF:0000003, GO:0006355=GO_REF:0000037, GO:0016575=PMID:11948178, GO:0005886=GO_REF:0000054, GO:0005634=PMID:11948178, GO:0046970=GO_REF:0000003, GO:0006351=GO_REF:0000037, GO:0097372=GO_REF:0000003, GO:0000118=PMID:11948178, GO:0016787=GO_REF:0000038, GO:0014003=GO_REF:0000019, GO:0004407=PMID:11948178, GO:0046969=GO_REF:0000003, GO:0008134=PMID:12711221, GO:0016568=PMID:12711221} Q96DB2 Histone deacetylase 11 protein 20100607 {GO:0032041=IEA, GO:0006355=IEA, GO:0016575=IDA, GO:0005886=IDA, GO:0005634=IDA, GO:0046970=IEA, GO:0006351=IEA, GO:0097372=IEA, GO:0000118=IDA, GO:0016787=IEA, GO:0014003=IEA, GO:0004407=IDA, GO:0046969=IEA, GO:0008134=TAS, GO:0016568=TAS} chromatin modification, histone deacetylation, oligodendrocyte development, regulation of transcription, DNA-dependent, transcription, DNA-dependent histone deacetylase complex, nucleus, plasma membrane NAD-dependent histone deacetylase activity (H3-K14 specific), NAD-dependent histone deacetylase activity (H3-K18 specific), NAD-dependent histone deacetylase activity (H3-K9 specific), NAD-dependent histone deacetylase activity (H4-K16 specific), histone deacetylase activity, hydrolase activity, transcription factor binding Human HDAC2 HPA UniProtKB {GO:0000792=GO_REF:0000019, GO:0005515=PMID:19497860, GO:0000790=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0005657=GO_REF:0000019, GO:0016581=PMID:17827154, GO:0016580=PMID:17827154, GO:0017053=GO_REF:0000019, GO:0045347=PMID:19041327, GO:0001103=PMID:22926524, GO:0000122=PMID:19276356, GO:0045786=Reactome:REACT_13695, GO:0090311=GO_REF:0000019, GO:0031490=GO_REF:0000019, GO:0016358=GO_REF:0000024, GO:0033558=PMID:19041327, GO:0032967=PMID:19041327, GO:0010977=PMID:18754010, GO:0005654=Reactome:REACT_25101, GO:0045893=PMID:19041327, GO:0061198=PMID:21093383, GO:0019899=PMID:11641274, GO:0045892=PMID:19276356, GO:0042733=PMID:21093383, GO:0008134=PMID:17827154, GO:0006344=PMID:19372552, GO:0008284=PMID:18347167, GO:0046970=GO_REF:0000003, GO:0005634=GO_REF:0000052, GO:0010870=PMID:18316616, GO:0043433=PMID:19041327, GO:0097372=GO_REF:0000003, GO:0051091=GO_REF:0000019, GO:0005737=PMID:12711221, GO:0061029=PMID:21093383, GO:0045944=PMID:19372552, GO:0042475=PMID:21093383, GO:0006338=PMID:17827154, GO:0004407=PMID:16642021, GO:0090090=GO_REF:0000019, GO:0046969=GO_REF:0000003, GO:0032041=GO_REF:0000003, GO:0005667=GO_REF:0000019, GO:0016575=PMID:19372552, GO:0043066=PMID:21093383, GO:0048011=Reactome:REACT_13776, GO:0060789=PMID:21093383, GO:0006351=GO_REF:0000037, GO:0045862=PMID:19041327, GO:0009913=PMID:21093383, GO:0043565=PMID:19276356, GO:0021766=GO_REF:0000019, GO:0035098=PMID:20075857, GO:0007596=Reactome:REACT_604, GO:0048714=GO_REF:0000019, GO:0003682=GO_REF:0000024} Q92769 Histone deacetylase 2 protein 20081203 {GO:0000792=IEA, GO:0005515=IPI, GO:0000790=IEA, GO:0003700=IEA, GO:0005657=IEA, GO:0016581=IDA, GO:0016580=IDA, GO:0017053=IEA, GO:0045347=IC, GO:0001103=IPI, GO:0000122=IMP, GO:0045786=TAS, GO:0090311=IEA, GO:0031490=IEA, GO:0016358=ISS, GO:0033558=IMP, GO:0032967=IC, GO:0010977=ISS, GO:0005654=TAS, GO:0045893=IC, GO:0061198=ISS, GO:0019899=IPI, GO:0045892=IMP, GO:0042733=ISS, GO:0008134=IPI, GO:0006344=IMP, GO:0008284=IMP, GO:0046970=IEA, GO:0005634=IDA, GO:0010870=IMP, GO:0043433=IMP, GO:0097372=IEA, GO:0051091=IEA, GO:0005737=TAS, GO:0061029=ISS, GO:0045944=IMP, GO:0042475=ISS, GO:0006338=IC, GO:0004407=IDA, GO:0090090=IEA, GO:0046969=IEA, GO:0032041=IEA, GO:0005667=IEA, GO:0016575=IMP, GO:0043066=ISS, GO:0048011=TAS, GO:0060789=ISS, GO:0006351=IEA, GO:0045862=IMP, GO:0009913=ISS, GO:0043565=IDA, GO:0021766=IEA, GO:0035098=IDA, GO:0007596=TAS, GO:0048714=IEA, GO:0003682=ISS} blood coagulation, chromatin remodeling, dendrite development, embryonic digit morphogenesis, epidermal cell differentiation, eyelid development in camera-type eye, fungiform papilla formation, hair follicle placode formation, hippocampus development, histone deacetylation, maintenance of chromatin silencing, negative regulation of MHC class II biosynthetic process, negative regulation of apoptotic process, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cell cycle, negative regulation of neuron projection development, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, neurotrophin TRK receptor signaling pathway, odontogenesis of dentin-containing tooth, positive regulation of cell proliferation, positive regulation of collagen biosynthetic process, positive regulation of oligodendrocyte differentiation, positive regulation of proteolysis, positive regulation of receptor biosynthetic process, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of protein deacetylation, transcription, DNA-dependent ESC/E(Z) complex, NuRD complex, Sin3 complex, cytoplasm, heterochromatin, nuclear chromatin, nucleoplasm, nucleus, replication fork, transcription factor complex, transcriptional repressor complex NAD-dependent histone deacetylase activity (H3-K14 specific), NAD-dependent histone deacetylase activity (H3-K18 specific), NAD-dependent histone deacetylase activity (H3-K9 specific), NAD-dependent histone deacetylase activity (H4-K16 specific), RNA polymerase II repressing transcription factor binding, chromatin DNA binding, chromatin binding, enzyme binding, histone deacetylase activity, protein binding, protein deacetylase activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human HDAC3 BHF-UCL UniProtKB {GO:0005515=PMID:18854353, GO:0042826=PMID:10869435, GO:0046970=GO_REF:0000003, GO:0005634=PMID:18347167, GO:0010832=PMID:10983972, GO:0044281=Reactome:REACT_111217, GO:0097372=GO_REF:0000003, GO:0005737=PMID:12711221, GO:0046329=PMID:11931768, GO:0007219=Reactome:REACT_118859, GO:0017053=PMID:11804585, GO:0040014=GO_REF:0000019, GO:0005876=PMID:18326024, GO:0004407=PMID:16924111, GO:0046969=GO_REF:0000003, GO:0006476=PMID:17172643, GO:0044255=Reactome:REACT_22279, GO:0032041=GO_REF:0000003, GO:0048011=Reactome:REACT_13776, GO:0043066=PMID:10777477, GO:0003714=PMID:12628926, GO:0000122=PMID:18854353, GO:0045786=Reactome:REACT_13695, GO:0051225=PMID:18326024, GO:0031490=GO_REF:0000019, GO:0032922=GO_REF:0000019, GO:0033558=PMID:17172643, GO:0006351=GO_REF:0000037, GO:0007346=GO_REF:0000019, GO:0000118=PMID:12711221, GO:0005654=Reactome:REACT_160192, GO:0019899=PMID:11641274, GO:0045892=PMID:16924111, GO:0016568=PMID:12711221, GO:0008134=PMID:12711221} O15379 Histone deacetylase 3 protein 20090803 {GO:0005515=IPI, GO:0042826=IPI, GO:0046970=IEA, GO:0005634=IDA, GO:0010832=IMP, GO:0044281=TAS, GO:0097372=IEA, GO:0005737=TAS, GO:0046329=IMP, GO:0007219=TAS, GO:0017053=IDA, GO:0040014=IEA, GO:0005876=IDA, GO:0004407=IMP, GO:0046969=IEA, GO:0006476=IDA, GO:0044255=TAS, GO:0032041=IEA, GO:0048011=TAS, GO:0043066=TAS, GO:0003714=IMP, GO:0000122=IDA, GO:0045786=TAS, GO:0051225=IMP, GO:0031490=IEA, GO:0032922=IEA, GO:0033558=IDA, GO:0006351=IEA, GO:0007346=IEA, GO:0000118=TAS, GO:0005654=TAS, GO:0019899=IPI, GO:0045892=IMP, GO:0016568=TAS, GO:0008134=TAS} Notch signaling pathway, cellular lipid metabolic process, chromatin modification, circadian regulation of gene expression, negative regulation of JNK cascade, negative regulation of apoptotic process, negative regulation of cell cycle, negative regulation of myotube differentiation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, neurotrophin TRK receptor signaling pathway, protein deacetylation, regulation of mitotic cell cycle, regulation of multicellular organism growth, small molecule metabolic process, spindle assembly, transcription, DNA-dependent cytoplasm, histone deacetylase complex, nucleoplasm, nucleus, spindle microtubule, transcriptional repressor complex NAD-dependent histone deacetylase activity (H3-K14 specific), NAD-dependent histone deacetylase activity (H3-K18 specific), NAD-dependent histone deacetylase activity (H3-K9 specific), NAD-dependent histone deacetylase activity (H4-K16 specific), chromatin DNA binding, enzyme binding, histone deacetylase activity, histone deacetylase binding, protein binding, protein deacetylase activity, transcription corepressor activity, transcription factor binding Human UniProtKB:P56524 HDAC4 BHF-UCL UniProtKB {GO:0005515=PMID:10869435, GO:0030018=GO_REF:0000019, GO:0031594=GO_REF:0000019, GO:0042641=GO_REF:0000019, GO:0044212=PMID:18850004, GO:0010832=PMID:10983972, GO:0017053=PMID:11804585, GO:0045820=GO_REF:0000024, GO:0019901=GO_REF:0000019, GO:0034983=PMID:18614528, GO:0003714=GO_REF:0000019, GO:0043393=PMID:19071119, GO:0048742=GO_REF:0000019, GO:0000122=PMID:19276356, GO:0030955=PMID:18614528, GO:0014894=GO_REF:0000024, GO:0033558=PMID:18614528, GO:0042113=PMID:12711221, GO:0001501=GO_REF:0000019, GO:0000118=PMID:11804585, GO:0002076=GO_REF:0000019, GO:0008270=PMID:18614528, GO:0045893=GO_REF:0000024, GO:0031672=GO_REF:0000019, GO:0045892=PMID:19276356, GO:0008134=PMID:19071119, GO:0008284=PMID:18850004, GO:0008285=GO_REF:0000019, GO:0042826=PMID:10869435, GO:0005634=PMID:10869435, GO:0046970=GO_REF:0000003, GO:0043433=PMID:18850004, GO:0005829=GO_REF:0000019, GO:0097372=GO_REF:0000003, GO:0051091=PMID:19071119, GO:0005737=PMID:10869435, GO:0006954=PMID:12711221, GO:0045944=GO_REF:0000024, GO:0030183=PMID:12711221, GO:0070491=PMID:11804585, GO:0014898=PMID:17011572, GO:0033235=PMID:17696781, GO:0006338=PMID:18850004, GO:0004407=PMID:10869435, GO:0033613=PMID:10983972, GO:0046969=GO_REF:0000003, GO:0070555=PMID:19281832, GO:0032041=GO_REF:0000003, GO:0070932=PMID:12590135, GO:0070933=PMID:12590135, GO:0016575=PMID:18850004, GO:0042493=GO_REF:0000019, GO:0010882=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0007399=PMID:12711221, GO:0043565=PMID:19276356, GO:0045668=GO_REF:0000019, GO:0016787=GO_REF:0000038} P56524 Histone deacetylase 4 protein 20100524 {GO:0005515=IPI, GO:0030018=IEA, GO:0031594=IEA, GO:0042641=IEA, GO:0044212=IDA, GO:0010832=IMP, GO:0017053=IDA, GO:0045820=ISS, GO:0019901=IEA, GO:0034983=IDA, GO:0003714=IEA, GO:0043393=IMP, GO:0048742=IEA, GO:0000122=IMP, GO:0030955=IDA, GO:0014894=ISS, GO:0033558=IDA, GO:0042113=TAS, GO:0001501=IEA, GO:0000118=IDA, GO:0002076=IEA, GO:0008270=IDA, GO:0045893=ISS, GO:0031672=IEA, GO:0045892=IMP, GO:0008134=IPI, GO:0008284=IMP, GO:0008285=IEA, GO:0042826=IPI, GO:0005634=IDA, GO:0046970=IEA, GO:0043433=IMP, GO:0005829=IEA, GO:0097372=IEA, GO:0051091=IMP, GO:0005737=IDA, GO:0006954=TAS, GO:0045944=ISS, GO:0030183=TAS, GO:0070491=IPI, GO:0014898=TAS, GO:0033235=IDA, GO:0006338=IDA, GO:0004407=IDA, GO:0033613=IPI, GO:0046969=IEA, GO:0070555=IMP, GO:0032041=IEA, GO:0070932=IDA, GO:0070933=IDA, GO:0016575=IMP, GO:0042493=IEA, GO:0010882=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0007399=TAS, GO:0043565=IDA, GO:0045668=IEA, GO:0016787=IEA} B cell activation, B cell differentiation, cardiac muscle hypertrophy in response to stress, chromatin remodeling, histone H3 deacetylation, histone H4 deacetylation, histone deacetylation, inflammatory response, negative regulation of cell proliferation, negative regulation of glycolysis, negative regulation of myotube differentiation, negative regulation of osteoblast differentiation, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, nervous system development, osteoblast development, peptidyl-lysine deacetylation, positive regulation of cell proliferation, positive regulation of protein sumoylation, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of cardiac muscle contraction by calcium ion signaling, regulation of protein binding, regulation of skeletal muscle fiber development, response to denervation involved in regulation of muscle adaptation, response to drug, response to interleukin-1, skeletal system development, transcription, DNA-dependent A band, Z disc, actomyosin, cytoplasm, cytosol, histone deacetylase complex, neuromuscular junction, nucleus, transcriptional repressor complex DNA binding, NAD-dependent histone deacetylase activity (H3-K14 specific), NAD-dependent histone deacetylase activity (H3-K18 specific), NAD-dependent histone deacetylase activity (H3-K9 specific), NAD-dependent histone deacetylase activity (H4-K16 specific), activating transcription factor binding, histone deacetylase activity, histone deacetylase binding, hydrolase activity, potassium ion binding, protein binding, protein deacetylase activity, protein kinase binding, repressing transcription factor binding, sequence-specific DNA binding, transcription corepressor activity, transcription factor binding, transcription regulatory region DNA binding, zinc ion binding Human HDAC5 HPA UniProtKB {GO:0005515=PMID:10869435, GO:0006342=PMID:10869435, GO:0044212=PMID:19351956, GO:0006325=PMID:12711221, GO:0010830=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0046970=GO_REF:0000003, GO:0010832=PMID:11081517, GO:0042220=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=GO_REF:0000019, GO:0007507=GO_REF:0000019, GO:0097372=GO_REF:0000003, GO:0051091=PMID:19071119, GO:0005737=GO_REF:0000052, GO:0006954=PMID:12711221, GO:0007219=Reactome:REACT_118859, GO:0045944=PMID:19071119, GO:0070491=PMID:12242305, GO:0030183=PMID:12711221, GO:0005080=PMID:20188095, GO:0090051=PMID:19351956, GO:0006338=PMID:10220385, GO:0004407=PMID:10869435, GO:0046969=GO_REF:0000003, GO:0032041=GO_REF:0000003, GO:0032869=PMID:18184930, GO:0016575=PMID:10869435, GO:0005794=GO_REF:0000052, GO:0003714=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0043393=PMID:19071119, GO:0000122=PMID:19351956, GO:0006351=GO_REF:0000037, GO:0042113=PMID:12711221, GO:0016604=GO_REF:0000019, GO:0045668=GO_REF:0000019, GO:0000118=PMID:12711221, GO:0002076=GO_REF:0000019, GO:0005654=Reactome:REACT_160192, GO:0045892=PMID:12711221, GO:0008134=PMID:19071119, GO:0016568=PMID:12711221} Q9UQL6 Histone deacetylase 5 protein 20120912 {GO:0005515=IPI, GO:0006342=TAS, GO:0044212=IDA, GO:0006325=TAS, GO:0010830=ISS, GO:0005634=IDA, GO:0046970=IEA, GO:0010832=IMP, GO:0042220=IEA, GO:0046872=IEA, GO:0005829=IEA, GO:0007507=IEA, GO:0097372=IEA, GO:0051091=IMP, GO:0005737=IDA, GO:0006954=TAS, GO:0007219=TAS, GO:0045944=IMP, GO:0070491=IPI, GO:0030183=TAS, GO:0005080=IPI, GO:0090051=IMP, GO:0006338=TAS, GO:0004407=IDA, GO:0046969=IEA, GO:0032041=IEA, GO:0032869=NAS, GO:0016575=IDA, GO:0005794=IDA, GO:0003714=IEA, GO:0005730=IDA, GO:0043393=IMP, GO:0000122=IMP, GO:0006351=IEA, GO:0042113=TAS, GO:0016604=IEA, GO:0045668=IEA, GO:0000118=TAS, GO:0002076=IEA, GO:0005654=TAS, GO:0045892=TAS, GO:0008134=IPI, GO:0016568=TAS} B cell activation, B cell differentiation, Notch signaling pathway, cellular response to insulin stimulus, chromatin modification, chromatin organization, chromatin remodeling, chromatin silencing, heart development, histone deacetylation, inflammatory response, negative regulation of cell migration involved in sprouting angiogenesis, negative regulation of myotube differentiation, negative regulation of osteoblast differentiation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, osteoblast development, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, regulation of myotube differentiation, regulation of protein binding, response to cocaine, transcription, DNA-dependent Golgi apparatus, cytoplasm, cytosol, histone deacetylase complex, nuclear body, nucleolus, nucleoplasm, nucleus NAD-dependent histone deacetylase activity (H3-K14 specific), NAD-dependent histone deacetylase activity (H3-K18 specific), NAD-dependent histone deacetylase activity (H3-K9 specific), NAD-dependent histone deacetylase activity (H4-K16 specific), histone deacetylase activity, metal ion binding, protein binding, protein kinase C binding, repressing transcription factor binding, transcription corepressor activity, transcription factor binding, transcription regulatory region DNA binding Human HDAC6 HPA UniProtKB {GO:0008017=PMID:19228685, GO:0005515=PMID:22645275, GO:0032418=PMID:16192271, GO:0043130=GO_REF:0000019, GO:0010469=PMID:19158084, GO:0070301=PMID:18606987, GO:0051354=PMID:18606987, GO:0008013=PMID:18356165, GO:0051879=PMID:15916966, GO:0006886=PMID:16192271, GO:0051788=PMID:14675537, GO:0071218=GO_REF:0000019, GO:0000209=GO_REF:0000019, GO:0034983=PMID:18606987, GO:0060765=PMID:18852123, GO:0048487=GO_REF:0000019, GO:0009636=PMID:19158084, GO:0043241=GO_REF:0000019, GO:0070848=PMID:18356165, GO:0043242=PMID:15916966, GO:0070845=PMID:14675537, GO:0060632=PMID:19228685, GO:0070846=PMID:19158084, GO:0000118=PMID:11948178, GO:0070840=PMID:14675537, GO:0070842=PMID:14675537, GO:0008270=GO_REF:0000002, GO:0019899=PMID:11861901, GO:0045892=PMID:11861901, GO:0031593=PMID:14675537, GO:0005881=GO_REF:0000019, GO:0048471=PMID:12024216, GO:0042826=PMID:12620231, GO:0046970=GO_REF:0000003, GO:0005634=GO_REF:0000052, GO:0035967=PMID:16192271, GO:0010870=PMID:18316616, GO:0005829=GO_REF:0000024, GO:0097372=GO_REF:0000003, GO:0005737=PMID:11861901, GO:0090035=PMID:19158084, GO:0004407=PMID:10220385, GO:0046969=GO_REF:0000003, GO:0031252=PMID:12024216, GO:0006476=PMID:15916966, GO:0032041=GO_REF:0000003, GO:0016575=PMID:10220385, GO:0010033=PMID:19158084, GO:0043065=PMID:18606987, GO:0016235=PMID:14675537, GO:0016234=PMID:16192271, GO:0043014=PMID:19228685, GO:0005875=PMID:19228685, GO:0005874=PMID:12620231, GO:0016236=PMID:16192271, GO:0048156=PMID:18636984, GO:0005730=GO_REF:0000052, GO:0009967=PMID:19158084, GO:0003779=GO_REF:0000037, GO:0010727=PMID:18606987, GO:0006351=GO_REF:0000037, GO:0045861=PMID:18356165, GO:0030286=PMID:14675537, GO:0016787=GO_REF:0000038, GO:0005901=PMID:18356165, GO:0042903=PMID:19228685, GO:0007026=GO_REF:0000019, GO:0090042=PMID:19228685, GO:0006515=PMID:14675537, GO:0010634=PMID:12024216, GO:0043162=GO_REF:0000019} Q9UBN7 Histone deacetylase 6 protein 20101115 {GO:0008017=IDA, GO:0005515=IPI, GO:0032418=IMP, GO:0043130=IEA, GO:0010469=IMP, GO:0070301=IMP, GO:0051354=IC, GO:0008013=IPI, GO:0051879=IDA, GO:0006886=IMP, GO:0051788=IMP, GO:0071218=IEA, GO:0000209=IEA, GO:0034983=IMP, GO:0060765=TAS, GO:0048487=IEA, GO:0009636=IMP, GO:0043241=IEA, GO:0070848=IMP, GO:0043242=IMP, GO:0070845=IMP, GO:0060632=IC, GO:0070846=IMP, GO:0000118=IDA, GO:0070840=IDA, GO:0070842=IMP, GO:0008270=IEA, GO:0019899=ISS, GO:0045892=ISS, GO:0031593=IDA, GO:0005881=IEA, GO:0048471=IDA, GO:0042826=IPI, GO:0046970=IEA, GO:0005634=IDA, GO:0035967=IMP, GO:0010870=IMP, GO:0005829=ISS, GO:0097372=IEA, GO:0005737=ISS, GO:0090035=IMP, GO:0004407=IDA, GO:0046969=IEA, GO:0031252=IDA, GO:0006476=IMP, GO:0032041=IEA, GO:0016575=IDA, GO:0010033=IMP, GO:0043065=IMP, GO:0016235=IDA, GO:0016234=IDA, GO:0043014=IDA, GO:0005875=IDA, GO:0005874=IDA, GO:0016236=IMP, GO:0048156=IDA, GO:0005730=IDA, GO:0009967=IMP, GO:0003779=IEA, GO:0010727=IC, GO:0006351=IEA, GO:0045861=IMP, GO:0030286=IDA, GO:0016787=IEA, GO:0005901=IDA, GO:0042903=IDA, GO:0007026=IEA, GO:0090042=IDA, GO:0006515=IMP, GO:0010634=IMP, GO:0043162=IEA} Hsp90 deacetylation, aggresome assembly, cellular response to hydrogen peroxide, cellular response to misfolded protein, cellular response to topologically incorrect protein, histone deacetylation, intracellular protein transport, lysosome localization, macroautophagy, misfolded or incompletely synthesized protein catabolic process, negative regulation of hydrogen peroxide metabolic process, negative regulation of microtubule depolymerization, negative regulation of oxidoreductase activity, negative regulation of protein complex disassembly, negative regulation of proteolysis, negative regulation of transcription, DNA-dependent, peptidyl-lysine deacetylation, polyubiquitinated misfolded protein transport, positive regulation of apoptotic process, positive regulation of chaperone-mediated protein complex assembly, positive regulation of epithelial cell migration, positive regulation of receptor biosynthetic process, positive regulation of signal transduction, protein complex disassembly, protein deacetylation, protein polyubiquitination, regulation of androgen receptor signaling pathway, regulation of microtubule-based movement, regulation of receptor activity, response to growth factor stimulus, response to misfolded protein, response to organic substance, response to toxic substance, transcription, DNA-dependent, tubulin deacetylation, ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway aggresome, caveola, cell leading edge, cytoplasm, cytoplasmic microtubule, cytosol, dynein complex, histone deacetylase complex, inclusion body, microtubule, microtubule associated complex, nucleolus, nucleus, perinuclear region of cytoplasm Hsp90 protein binding, NAD-dependent histone deacetylase activity (H3-K14 specific), NAD-dependent histone deacetylase activity (H3-K18 specific), NAD-dependent histone deacetylase activity (H3-K9 specific), NAD-dependent histone deacetylase activity (H4-K16 specific), actin binding, alpha-tubulin binding, beta-catenin binding, beta-tubulin binding, dynein complex binding, enzyme binding, histone deacetylase activity, histone deacetylase binding, hydrolase activity, microtubule binding, polyubiquitin binding, protein binding, tau protein binding, tubulin deacetylase activity, ubiquitin binding, zinc ion binding NOT Human HDAC7 HPA UniProtKB {GO:0005515=PMID:22155184, GO:0046970=GO_REF:0000003, GO:0005634=PMID:16980613, GO:0046872=GO_REF:0000037, GO:0097372=GO_REF:0000003, GO:0071889=PMID:16980613, GO:0005737=GO_REF:0000052, GO:0007219=Reactome:REACT_118859, GO:0070491=PMID:17360565, GO:0005080=PMID:20188095, GO:0090050=PMID:19351956, GO:0004407=GO_REF:0000002, GO:0033613=PMID:20590529, GO:0046969=GO_REF:0000003, GO:0032703=PMID:17360565, GO:0032041=GO_REF:0000003, GO:0019901=PMID:16980613, GO:0003714=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0000118=GO_REF:0000002, GO:0045668=PMID:17997710, GO:0016787=GO_REF:0000038, GO:0003682=GO_REF:0000019, GO:0007043=GO_REF:0000019, GO:0005654=Reactome:REACT_160192, GO:0001570=GO_REF:0000019} Q8WUI4 Histone deacetylase 7 protein 20101115 {GO:0005515=IPI, GO:0046970=IEA, GO:0005634=IDA, GO:0046872=IEA, GO:0097372=IEA, GO:0071889=IDA, GO:0005737=IDA, GO:0007219=TAS, GO:0070491=IPI, GO:0005080=IPI, GO:0090050=IMP, GO:0004407=IEA, GO:0033613=IPI, GO:0046969=IEA, GO:0032703=IDA, GO:0032041=IEA, GO:0019901=IPI, GO:0003714=IEA, GO:0000122=IEA, GO:0006351=IEA, GO:0000118=IEA, GO:0045668=IMP, GO:0016787=IEA, GO:0003682=IEA, GO:0007043=IEA, GO:0005654=TAS, GO:0001570=IEA} Notch signaling pathway, cell-cell junction assembly, negative regulation of interleukin-2 production, negative regulation of osteoblast differentiation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of cell migration involved in sprouting angiogenesis, transcription, DNA-dependent, vasculogenesis cytoplasm, histone deacetylase complex, nucleoplasm, nucleus 14-3-3 protein binding, NAD-dependent histone deacetylase activity (H3-K14 specific), NAD-dependent histone deacetylase activity (H3-K18 specific), NAD-dependent histone deacetylase activity (H3-K9 specific), NAD-dependent histone deacetylase activity (H4-K16 specific), activating transcription factor binding, chromatin binding, histone deacetylase activity, hydrolase activity, metal ion binding, protein binding, protein kinase C binding, protein kinase binding, repressing transcription factor binding, transcription corepressor activity Human HDAC8 Reactome UniProtKB {GO:0032041=GO_REF:0000003, GO:0000236=Reactome:REACT_682, GO:0046970=GO_REF:0000003, GO:0005634=PMID:12711221, GO:0000122=PMID:10748112, GO:0000228=PMID:10748112, GO:0071922=PMID:22885700, GO:0006351=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_150294, GO:0006333=PMID:10748112, GO:0097372=GO_REF:0000003, GO:0005737=PMID:12711221, GO:0000118=PMID:12711221, GO:0016787=GO_REF:0000038, GO:0000087=Reactome:REACT_910, GO:0007062=PMID:22885700, GO:0004407=PMID:12711221, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0046969=GO_REF:0000003, GO:0008134=PMID:12711221, GO:0016568=PMID:12711221} Q9BY41 Histone deacetylase 8 protein 20121101 {GO:0032041=IEA, GO:0000236=TAS, GO:0046970=IEA, GO:0005634=TAS, GO:0000122=TAS, GO:0000228=TAS, GO:0071922=IMP, GO:0006351=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0006333=TAS, GO:0097372=IEA, GO:0005737=TAS, GO:0000118=TAS, GO:0016787=IEA, GO:0000087=TAS, GO:0007062=IMP, GO:0004407=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0046969=IEA, GO:0008134=TAS, GO:0016568=TAS} M phase of mitotic cell cycle, chromatin assembly or disassembly, chromatin modification, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, negative regulation of transcription from RNA polymerase II promoter, regulation of cohesin localization to chromatin, sister chromatid cohesion, transcription, DNA-dependent cytoplasm, cytosol, histone deacetylase complex, nuclear chromosome, nucleus NAD-dependent histone deacetylase activity (H3-K14 specific), NAD-dependent histone deacetylase activity (H3-K18 specific), NAD-dependent histone deacetylase activity (H3-K9 specific), NAD-dependent histone deacetylase activity (H4-K16 specific), histone deacetylase activity, hydrolase activity, metal ion binding, transcription factor binding Human HDAC9 BHF-UCL UniProtKB {GO:0005515=PMID:16147992, GO:0042826=PMID:12590135, GO:0046970=GO_REF:0000003, GO:0005634=PMID:12590135, GO:0046872=GO_REF:0000037, GO:0007507=GO_REF:0000024, GO:0097372=GO_REF:0000003, GO:0005737=PMID:12590135, GO:0006954=PMID:12711221, GO:0007219=Reactome:REACT_118859, GO:0030183=PMID:12711221, GO:0070491=PMID:17360565, GO:0005080=PMID:20188095, GO:0051153=GO_REF:0000024, GO:0090050=PMID:19351956, GO:0004407=PMID:11535832, GO:0046969=GO_REF:0000003, GO:0032041=GO_REF:0000003, GO:0070932=PMID:12590135, GO:0005667=PMID:19303849, GO:0070933=PMID:12590135, GO:0032869=PMID:19303849, GO:0016575=PMID:11535832, GO:0034983=PMID:11535832, GO:0003714=GO_REF:0000024, GO:0048742=GO_REF:0000024, GO:0000122=PMID:11535832, GO:0033558=PMID:11535832, GO:0006351=GO_REF:0000037, GO:0042113=PMID:12711221, GO:0035097=GO_REF:0000024, GO:0000118=PMID:12711221, GO:0005654=Reactome:REACT_160192, GO:0045892=PMID:11535832, GO:0008134=PMID:19303849} Q9UKV0 Histone deacetylase 9 protein 20100524 {GO:0005515=IPI, GO:0042826=IPI, GO:0046970=IEA, GO:0005634=IDA, GO:0046872=IEA, GO:0007507=ISS, GO:0097372=IEA, GO:0005737=IDA, GO:0006954=TAS, GO:0007219=TAS, GO:0030183=TAS, GO:0070491=IPI, GO:0005080=IPI, GO:0051153=ISS, GO:0090050=IMP, GO:0004407=IDA, GO:0046969=IEA, GO:0032041=IEA, GO:0070932=IDA, GO:0005667=IDA, GO:0070933=IDA, GO:0032869=IDA, GO:0016575=IDA, GO:0034983=IDA, GO:0003714=ISS, GO:0048742=ISS, GO:0000122=IDA, GO:0033558=IDA, GO:0006351=IEA, GO:0042113=TAS, GO:0035097=ISS, GO:0000118=TAS, GO:0005654=TAS, GO:0045892=IDA, GO:0008134=IPI} B cell activation, B cell differentiation, Notch signaling pathway, cellular response to insulin stimulus, heart development, histone H3 deacetylation, histone H4 deacetylation, histone deacetylation, inflammatory response, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, peptidyl-lysine deacetylation, positive regulation of cell migration involved in sprouting angiogenesis, regulation of skeletal muscle fiber development, regulation of striated muscle cell differentiation, transcription, DNA-dependent cytoplasm, histone deacetylase complex, histone methyltransferase complex, nucleoplasm, nucleus, transcription factor complex NAD-dependent histone deacetylase activity (H3-K14 specific), NAD-dependent histone deacetylase activity (H3-K18 specific), NAD-dependent histone deacetylase activity (H3-K9 specific), NAD-dependent histone deacetylase activity (H4-K16 specific), histone deacetylase activity, histone deacetylase binding, metal ion binding, protein binding, protein deacetylase activity, protein kinase C binding, repressing transcription factor binding, transcription corepressor activity, transcription factor binding Human HDC Reactome UniProtKB {GO:0001694=PMID:22767596, GO:0034641=Reactome:REACT_13, GO:0006520=GO_REF:0000002, GO:0006547=PMID:1487235, GO:0006548=Reactome:REACT_1249, GO:0030170=GO_REF:0000002, GO:0016831=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0004398=Reactome:REACT_115661, GO:0042423=GO_REF:0000037, GO:0005829=Reactome:REACT_115661} P19113 Histidine decarboxylase protein 20120112 {GO:0001694=IDA, GO:0034641=TAS, GO:0006520=IEA, GO:0006547=TAS, GO:0006548=TAS, GO:0030170=IEA, GO:0016831=IEA, GO:0044281=TAS, GO:0004398=TAS, GO:0042423=IEA, GO:0005829=TAS} catecholamine biosynthetic process, cellular amino acid metabolic process, cellular nitrogen compound metabolic process, histamine biosynthetic process, histidine catabolic process, histidine metabolic process, small molecule metabolic process cytosol carboxy-lyase activity, histidine decarboxylase activity, pyridoxal phosphate binding Human HDDC2 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0005739=GO_REF:0000019, GO:0008081=GO_REF:0000002, GO:0046872=GO_REF:0000002} Q7Z4H3 HD domain-containing protein 2 protein 20130415 {GO:0005515=IPI, GO:0005739=IEA, GO:0008081=IEA, GO:0046872=IEA} mitochondrion metal ion binding, phosphoric diester hydrolase activity, protein binding Human UniProtKB:Q76353 HDDC3 UniProtKB UniProtKB {GO:0008893=GO_REF:0000003, GO:0003824=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q8N4P3 Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 protein 20130413 {GO:0008893=IEA, GO:0003824=IEA, GO:0046872=IEA} catalytic activity, guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity, metal ion binding Human EC:3.1.7.2 HDGF BHF-UCL UniProtKB {GO:0008283=PMID:7929202, GO:0001106=PMID:19162039, GO:0000122=PMID:19162039, GO:0003677=GO_REF:0000037, GO:0030968=Reactome:REACT_18356, GO:0001222=PMID:19162039, GO:0007165=PMID:7929202, GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000037, GO:0017053=PMID:19162039, GO:0005654=Reactome:REACT_115773, GO:0006987=Reactome:REACT_18368, GO:0008201=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0008083=GO_REF:0000037} P51858 Hepatoma-derived growth factor protein 20121026 {GO:0008283=TAS, GO:0001106=IDA, GO:0000122=IDA, GO:0003677=IEA, GO:0030968=TAS, GO:0001222=IPI, GO:0007165=NAS, GO:0005737=IEA, GO:0000166=IEA, GO:0017053=IDA, GO:0005654=TAS, GO:0006987=TAS, GO:0008201=IEA, GO:0044267=TAS, GO:0008083=IEA} activation of signaling protein activity involved in unfolded protein response, cell proliferation, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, negative regulation of transcription from RNA polymerase II promoter, signal transduction cytoplasm, nucleoplasm, transcriptional repressor complex DNA binding, RNA polymerase II transcription corepressor activity, growth factor activity, heparin binding, nucleotide binding, transcription corepressor binding Human UniProtKB:Q13363 HDHD2 UniProtKB UniProtKB {GO:0016787=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q9H0R4 Haloacid dehalogenase-like hydrolase domain-containing protein 2 protein 20130413 {GO:0016787=IEA, GO:0046872=IEA} hydrolase activity, metal ion binding Human UniProtKB-KW:KW-0479 HDHD3 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0005739=GO_REF:0000019, GO:0008967=GO_REF:0000002} Q9BSH5 Haloacid dehalogenase-like hydrolase domain-containing protein 3 protein 20130415 {GO:0005515=IPI, GO:0005739=IEA, GO:0008967=IEA} mitochondrion phosphoglycolate phosphatase activity, protein binding Human UniProtKB:Q15645 HDLBP HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005886=PMID:1318310, GO:0034364=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0006869=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008289=PMID:1318310, GO:0008203=GO_REF:0000037} Q00341 Vigilin protein 20080818 {GO:0005737=IDA, GO:0005886=TAS, GO:0034364=IEA, GO:0003723=IEA, GO:0006869=IEA, GO:0005634=IEA, GO:0008289=TAS, GO:0008203=IEA} cholesterol metabolic process, lipid transport cytoplasm, high-density lipoprotein particle, nucleus, plasma membrane RNA binding, lipid binding Human HDX UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0005634=GO_REF:0000039} Q7Z353 Highly divergent homeobox protein 20130413 {GO:0043565=IEA, GO:0003700=IEA, GO:0005634=IEA} nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0191 HEATR1 HPA UniProtKB {GO:0005515=PMID:22190034, GO:0005739=GO_REF:0000052, GO:0030529=GO_REF:0000037, GO:0006364=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9H583 HEAT repeat-containing protein 1 protein 20120912 {GO:0005515=IPI, GO:0005739=IDA, GO:0030529=IEA, GO:0006364=IEA, GO:0005730=IDA, GO:0005634=IDA} rRNA processing mitochondrion, nucleolus, nucleus, ribonucleoprotein complex protein binding Human HEATR2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q86Y56 HEAT repeat-containing protein 2 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 HEATR3 null null {} null null null null {} null null null HEATR5A null null {} null null null null {} null null null HEATR5B null null {} null null null null {} null null null HEATR6 null null {} null null null null {} null null null HEBP1 Reactome UniProtKB {GO:0005739=GO_REF:0000019, GO:0007623=PMID:10640688, GO:0005576=Reactome:REACT_22289, GO:0020037=GO_REF:0000024, GO:0005829=GO_REF:0000019} Q9NRV9 Heme-binding protein 1 protein 20091104 {GO:0005739=IEA, GO:0007623=TAS, GO:0005576=TAS, GO:0020037=ISS, GO:0005829=IEA} circadian rhythm cytosol, extracellular region, mitochondrion heme binding Human HEBP2 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0005737=PMID:17098234} Q9Y5Z4 Heme-binding protein 2 protein 20090915 {GO:0005739=IEA, GO:0005737=IDA} cytoplasm, mitochondrion Human HECA UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0030323=PMID:11696983, GO:0005575=GO_REF:0000015} Q9UBI9 Headcase protein homolog protein 20061026 {GO:0003674=ND, GO:0030323=NAS, GO:0005575=ND} respiratory tube development cellular_component molecular_function Human HECTD1 UniProtKB UniProtKB {GO:0005515=PMID:12421765, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000033, GO:0004842=GO_REF:0000033, GO:0042787=GO_REF:0000033, GO:0001843=GO_REF:0000019, GO:0005634=GO_REF:0000033, GO:0007155=GO_REF:0000002, GO:0046872=GO_REF:0000002} Q9ULT8 E3 ubiquitin-protein ligase HECTD1 protein 20100615 {GO:0005515=IPI, GO:0005622=IEA, GO:0005737=IBA, GO:0004842=IBA, GO:0042787=IBA, GO:0001843=IEA, GO:0005634=IBA, GO:0007155=IEA, GO:0046872=IEA} cell adhesion, neural tube closure, protein ubiquitination involved in ubiquitin-dependent protein catabolic process cytoplasm, intracellular, nucleus metal ion binding, protein binding, ubiquitin-protein ligase activity Human UniProtKB:Q8N6C5 HECTD2 RefGenome UniProtKB {GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000033, GO:0004842=GO_REF:0000033, GO:0042787=GO_REF:0000033, GO:0005634=GO_REF:0000033} Q5U5R9 Probable E3 ubiquitin-protein ligase HECTD2 protein 20110204 {GO:0005622=IEA, GO:0005737=IBA, GO:0004842=IBA, GO:0042787=IBA, GO:0005634=IBA} protein ubiquitination involved in ubiquitin-dependent protein catabolic process cytoplasm, intracellular, nucleus ubiquitin-protein ligase activity Human PANTHER:PTN000134256 HECTD3 UniProtKB UniProtKB {GO:0005515=PMID:18194665, GO:0019905=GO_REF:0000019, GO:0048471=GO_REF:0000024, GO:0004842=GO_REF:0000024, GO:0005737=GO_REF:0000033, GO:0042787=GO_REF:0000033, GO:0043161=PMID:18194665, GO:0005634=GO_REF:0000033} Q5T447 E3 ubiquitin-protein ligase HECTD3 protein 20100607 {GO:0005515=IPI, GO:0019905=IEA, GO:0048471=ISS, GO:0004842=ISS, GO:0005737=IBA, GO:0042787=IBA, GO:0043161=IDA, GO:0005634=IBA} proteasomal ubiquitin-dependent protein catabolic process, protein ubiquitination involved in ubiquitin-dependent protein catabolic process cytoplasm, nucleus, perinuclear region of cytoplasm protein binding, syntaxin binding, ubiquitin-protein ligase activity Human UniProtKB:Q9H2D6 HECW1 HPA UniProtKB {GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0004842=GO_REF:0000033, GO:0042787=GO_REF:0000033, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q76N89 E3 ubiquitin-protein ligase HECW1 protein 20101115 {GO:0005622=IEA, GO:0005737=IDA, GO:0004842=IBA, GO:0042787=IBA, GO:0005730=IDA, GO:0005634=IDA} protein ubiquitination involved in ubiquitin-dependent protein catabolic process cytoplasm, intracellular, nucleolus, nucleus ubiquitin-protein ligase activity Human HECW2 RefGenome UniProtKB {GO:0005737=GO_REF:0000033, GO:0004842=GO_REF:0000033, GO:0042787=GO_REF:0000033, GO:0005634=GO_REF:0000033} Q9P2P5 E3 ubiquitin-protein ligase HECW2 protein 20110204 {GO:0005737=IBA, GO:0004842=IBA, GO:0042787=IBA, GO:0005634=IBA} protein ubiquitination involved in ubiquitin-dependent protein catabolic process cytoplasm, nucleus ubiquitin-protein ligase activity Human PANTHER:PTN000134256 HEG1 UniProtKB UniProtKB {GO:0030324=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0003281=GO_REF:0000019, GO:0048845=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0060039=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0045216=GO_REF:0000019, GO:0003209=GO_REF:0000019, GO:0003017=GO_REF:0000019, GO:0035264=GO_REF:0000019, GO:0001886=GO_REF:0000019, GO:0005911=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0001570=GO_REF:0000019, GO:0050878=GO_REF:0000019, GO:0001945=GO_REF:0000019, GO:0009897=GO_REF:0000019} Q9ULI3 Protein HEG homolog 1 protein 20130413 {GO:0030324=IEA, GO:0005509=IEA, GO:0005576=IEA, GO:0003281=IEA, GO:0048845=IEA, GO:0009791=IEA, GO:0060039=IEA, GO:0001701=IEA, GO:0045216=IEA, GO:0003209=IEA, GO:0003017=IEA, GO:0035264=IEA, GO:0001886=IEA, GO:0005911=IEA, GO:0016021=IEA, GO:0001570=IEA, GO:0050878=IEA, GO:0001945=IEA, GO:0009897=IEA} cardiac atrium morphogenesis, cell-cell junction organization, endothelial cell morphogenesis, in utero embryonic development, lung development, lymph circulation, lymph vessel development, multicellular organism growth, pericardium development, post-embryonic development, regulation of body fluid levels, vasculogenesis, venous blood vessel morphogenesis, ventricular septum development cell-cell junction, external side of plasma membrane, extracellular region, integral to membrane calcium ion binding Human UniProtKB-SubCell:SL-0243 HELB UniProtKB UniProtKB {GO:0006260=PMID:12181327, GO:0043141=PMID:12181327, GO:0004003=GO_REF:0000002, GO:0017116=PMID:12181327, GO:0005658=PMID:12181327, GO:0006269=PMID:12181327, GO:0005524=GO_REF:0000037} Q8NG08 DNA helicase B protein 20080124 {GO:0006260=IMP, GO:0043141=IDA, GO:0004003=IEA, GO:0017116=IDA, GO:0005658=IDA, GO:0006269=IDA, GO:0005524=IEA} DNA replication, DNA replication, synthesis of RNA primer alpha DNA polymerase:primase complex ATP binding, ATP-dependent 5'-3' DNA helicase activity, ATP-dependent DNA helicase activity, single-stranded DNA-dependent ATP-dependent DNA helicase activity Human HELLS InterPro UniProtKB {GO:0031508=GO_REF:0000024, GO:0043066=GO_REF:0000019, GO:0006346=GO_REF:0000024, GO:0001655=GO_REF:0000019, GO:0004386=GO_REF:0000002, GO:0007275=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0007067=GO_REF:0000037, GO:0010216=GO_REF:0000024, GO:0005721=GO_REF:0000024, GO:0003682=GO_REF:0000019, GO:0046651=GO_REF:0000024, GO:0000775=GO_REF:0000024, GO:0051301=GO_REF:0000037} Q9NW36 cDNA FLJ10339 fis, clone NT2RM2000740, weakly similar to POSSIBLE GLOBAL TRANSCRIPTION ACTIVATOR SNF2L protein 20130413 {GO:0031508=ISS, GO:0043066=IEA, GO:0006346=ISS, GO:0001655=IEA, GO:0004386=IEA, GO:0007275=ISS, GO:0005634=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0005524=IEA, GO:0006351=IEA, GO:0007067=IEA, GO:0010216=ISS, GO:0005721=ISS, GO:0003682=IEA, GO:0046651=ISS, GO:0000775=ISS, GO:0051301=IEA} cell division, centromeric heterochromatin assembly, lymphocyte proliferation, maintenance of DNA methylation, methylation-dependent chromatin silencing, mitosis, multicellular organismal development, negative regulation of apoptotic process, transcription, DNA-dependent, urogenital system development centromeric heterochromatin, chromosome, centromeric region, nucleus ATP binding, DNA binding, chromatin binding, helicase activity, nucleic acid binding Human InterPro:IPR001650 HELQ HPA UniProtKB {GO:0008026=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0004386=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q8TDG4 Helicase POLQ-like protein 20110516 {GO:0008026=IEA, GO:0005730=IDA, GO:0004386=IEA, GO:0005634=IDA, GO:0003676=IEA, GO:0005524=IEA} nucleolus, nucleus ATP binding, ATP-dependent helicase activity, helicase activity, nucleic acid binding NOT Human HELT UniProtKB UniProtKB {GO:0021858=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0006355=GO_REF:0000038, GO:0003700=GO_REF:0000019, GO:0005634=GO_REF:0000038, GO:0010259=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0007417=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000038, GO:0042803=GO_REF:0000019, GO:0001967=GO_REF:0000019, GO:0035264=GO_REF:0000019, GO:0046983=GO_REF:0000002} B7ZMI7 Hairy and enhancer of split-related protein HELT protein 20130413 {GO:0021858=IEA, GO:0005667=IEA, GO:0006355=IEA, GO:0003700=IEA, GO:0005634=IEA, GO:0010259=IEA, GO:0000122=IEA, GO:0007417=IEA, GO:0009791=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0042803=IEA, GO:0001967=IEA, GO:0035264=IEA, GO:0046983=IEA} GABAergic neuron differentiation in basal ganglia, central nervous system development, multicellular organism growth, multicellular organismal aging, negative regulation of transcription from RNA polymerase II promoter, post-embryonic development, regulation of transcription, DNA-dependent, suckling behavior, transcription, DNA-dependent nucleus, transcription factor complex DNA binding, protein dimerization activity, protein homodimerization activity, sequence-specific DNA binding transcription factor activity Human UniProtKB-KW:KW-0805 HELZ UniProtKB UniProtKB {GO:0004386=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} P42694 Probable helicase with zinc finger domain protein 20130413 {GO:0004386=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0005524=IEA} nucleus ATP binding, helicase activity, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 HEMGN IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0045667=GO_REF:0000019, GO:0005654=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q9BXL5 Hemogen protein 20130415 {GO:0005515=IPI, GO:0045667=IEA, GO:0005654=IEA, GO:0007275=IEA, GO:0030154=IEA} cell differentiation, multicellular organismal development, regulation of osteoblast differentiation nucleoplasm protein binding Human UniProtKB:Q13363 HENMT1 UniProtKB UniProtKB {GO:0001510=GO_REF:0000024, GO:0003723=GO_REF:0000037, GO:0034587=GO_REF:0000024, GO:0043186=GO_REF:0000024, GO:0031047=GO_REF:0000037, GO:0008171=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0008173=GO_REF:0000024} Q5T8I9 Small RNA 2'-O-methyltransferase protein 20110222 {GO:0001510=ISS, GO:0003723=IEA, GO:0034587=ISS, GO:0043186=ISS, GO:0031047=IEA, GO:0008171=ISS, GO:0046872=IEA, GO:0008173=ISS} RNA methylation, gene silencing by RNA, piRNA metabolic process P granule O-methyltransferase activity, RNA binding, RNA methyltransferase activity, metal ion binding Human UniProtKB:Q568P9 HERC1 PINC UniProtKB {GO:0005086=PMID:8861955, GO:0005737=PMID:8861955, GO:0004842=GO_REF:0000002, GO:0005794=GO_REF:0000039, GO:0016020=GO_REF:0000039, GO:0006810=GO_REF:0000037, GO:0005829=GO_REF:0000039} Q15751 Probable E3 ubiquitin-protein ligase HERC1 protein 20030904 {GO:0005086=TAS, GO:0005737=TAS, GO:0004842=IEA, GO:0005794=IEA, GO:0016020=IEA, GO:0006810=IEA, GO:0005829=IEA} transport Golgi apparatus, cytoplasm, cytosol, membrane ARF guanyl-nucleotide exchange factor activity, ubiquitin-protein ligase activity Human HERC2 UniProtKB UniProtKB {GO:0005515=PMID:20023648, GO:0032183=PMID:22508508, GO:0004842=PMID:20304803, GO:0016567=PMID:20304803, GO:0005814=GO_REF:0000039, GO:0005743=GO_REF:0000019, GO:0005634=PMID:20304803, GO:0007283=GO_REF:0000019, GO:0006886=PMID:9949213, GO:0006974=PMID:22508508, GO:0005085=PMID:9949213, GO:0005737=PMID:20304803, GO:0006281=PMID:20023648, GO:0042787=GO_REF:0000033, GO:0008270=GO_REF:0000002, GO:0031625=PMID:22508508, GO:0020037=GO_REF:0000002} O95714 E3 ubiquitin-protein ligase HERC2 protein 20110413 {GO:0005515=IPI, GO:0032183=IDA, GO:0004842=IDA, GO:0016567=IDA, GO:0005814=IEA, GO:0005743=IEA, GO:0005634=IDA, GO:0007283=IEA, GO:0006886=NAS, GO:0006974=IDA, GO:0005085=NAS, GO:0005737=IDA, GO:0006281=IDA, GO:0042787=IBA, GO:0008270=IEA, GO:0031625=IPI, GO:0020037=IEA} DNA repair, intracellular protein transport, protein ubiquitination, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, response to DNA damage stimulus, spermatogenesis centriole, cytoplasm, mitochondrial inner membrane, nucleus SUMO binding, guanyl-nucleotide exchange factor activity, heme binding, protein binding, ubiquitin protein ligase binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:O76064 HERC3 HPA UniProtKB {GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0004842=GO_REF:0000033, GO:0042787=GO_REF:0000033, GO:0016023=GO_REF:0000039, GO:0005634=GO_REF:0000033} Q15034 Probable E3 ubiquitin-protein ligase HERC3 protein 20110516 {GO:0005622=IEA, GO:0005737=IDA, GO:0004842=IBA, GO:0042787=IBA, GO:0016023=IEA, GO:0005634=IBA} protein ubiquitination involved in ubiquitin-dependent protein catabolic process cytoplasm, cytoplasmic membrane-bounded vesicle, intracellular, nucleus ubiquitin-protein ligase activity Human HERC4 UniProtKB UniProtKB {GO:0005737=GO_REF:0000033, GO:0004842=GO_REF:0000033, GO:0042787=GO_REF:0000033, GO:0005634=GO_REF:0000033, GO:0007283=PMID:17967448, GO:0030154=GO_REF:0000037, GO:0005829=GO_REF:0000039} Q5GLZ8 Probable E3 ubiquitin-protein ligase HERC4 protein 20110413 {GO:0005737=IBA, GO:0004842=IBA, GO:0042787=IBA, GO:0005634=IBA, GO:0007283=ISS, GO:0030154=IEA, GO:0005829=IEA} cell differentiation, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, spermatogenesis cytoplasm, cytosol, nucleus ubiquitin-protein ligase activity Human UniProtKB:Q6PAV2 HERC5 Reactome UniProtKB {GO:0005515=PMID:20308324, GO:0050688=PMID:20308324, GO:0004842=GO_REF:0000033, GO:0048471=GO_REF:0000039, GO:0032020=PMID:20308324, GO:0019221=Reactome:REACT_25229, GO:0005634=GO_REF:0000033, GO:0000079=PMID:10581175, GO:0005829=Reactome:REACT_116157, GO:0005622=GO_REF:0000002, GO:0051607=GO_REF:0000037, GO:0005737=GO_REF:0000033, GO:0042787=GO_REF:0000033, GO:0045087=Reactome:REACT_6802, GO:0032480=Reactome:REACT_25271, GO:0042296=PMID:20308324} Q9UII4 E3 ISG15--protein ligase HERC5 protein 20100823 {GO:0005515=IPI, GO:0050688=IDA, GO:0004842=IBA, GO:0048471=IEA, GO:0032020=IDA, GO:0019221=TAS, GO:0005634=IBA, GO:0000079=TAS, GO:0005829=TAS, GO:0005622=IEA, GO:0051607=IEA, GO:0005737=IBA, GO:0042787=IBA, GO:0045087=TAS, GO:0032480=TAS, GO:0042296=IDA} ISG15-protein conjugation, cytokine-mediated signaling pathway, defense response to virus, innate immune response, negative regulation of type I interferon production, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of defense response to virus cytoplasm, cytosol, intracellular, nucleus, perinuclear region of cytoplasm ISG15 ligase activity, protein binding, ubiquitin-protein ligase activity Human HERC6 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0004842=GO_REF:0000033, GO:0042787=GO_REF:0000033, GO:0005634=GO_REF:0000052, GO:0005829=GO_REF:0000039} Q8IVU3 Probable E3 ubiquitin-protein ligase HERC6 protein 20110516 {GO:0005737=IDA, GO:0004842=IBA, GO:0042787=IBA, GO:0005634=IDA, GO:0005829=IEA} protein ubiquitination involved in ubiquitin-dependent protein catabolic process cytoplasm, cytosol, nucleus ubiquitin-protein ligase activity Human HERPUD1 Reactome UniProtKB {GO:0006986=PMID:10922362, GO:0003674=GO_REF:0000015, GO:0006511=GO_REF:0000019, GO:0005789=Reactome:REACT_116082, GO:0006874=GO_REF:0000019, GO:0031396=GO_REF:0000019, GO:0016021=GO_REF:0000019, GO:0006987=Reactome:REACT_18277, GO:0043154=GO_REF:0000019, GO:0044267=Reactome:REACT_17015, GO:0030968=Reactome:REACT_18356, GO:0032092=GO_REF:0000019} Q15011 Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein protein 20130301 {GO:0006986=IEP, GO:0003674=ND, GO:0006511=IEA, GO:0005789=TAS, GO:0006874=IEA, GO:0031396=IEA, GO:0016021=IEA, GO:0006987=TAS, GO:0043154=IEA, GO:0044267=TAS, GO:0030968=TAS, GO:0032092=IEA} activation of signaling protein activity involved in unfolded protein response, cellular calcium ion homeostasis, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of protein binding, regulation of protein ubiquitination, response to unfolded protein, ubiquitin-dependent protein catabolic process endoplasmic reticulum membrane, integral to membrane molecular_function Human HERPUD2 ENSEMBL UniProtKB {GO:0006986=GO_REF:0000037, GO:0007283=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q9BSE4 Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein protein 20130413 {GO:0006986=IEA, GO:0007283=IEA, GO:0016021=IEA} response to unfolded protein, spermatogenesis integral to membrane Human Ensembl:ENSMUSP00000008573 HES1 BHF-UCL UniProtKB {GO:0005515=PMID:12535671, GO:0071820=GO_REF:0000024, GO:0003700=PMID:17681138, GO:0021555=GO_REF:0000019, GO:0061106=GO_REF:0000019, GO:0045598=GO_REF:0000019, GO:0021558=GO_REF:0000019, GO:0021557=GO_REF:0000019, GO:0046331=GO_REF:0000019, GO:0072282=GO_REF:0000019, GO:0048844=GO_REF:0000024, GO:0048538=GO_REF:0000024, GO:0003281=GO_REF:0000024, GO:0060675=GO_REF:0000019, GO:0021861=GO_REF:0000024, GO:0042803=GO_REF:0000024, GO:0007224=GO_REF:0000019, GO:0003143=GO_REF:0000024, GO:0061009=GO_REF:0000019, GO:0007219=Reactome:REACT_118859, GO:0060716=GO_REF:0000019, GO:0045747=GO_REF:0000019, GO:0000122=PMID:12535671, GO:0072049=GO_REF:0000019, GO:0060037=GO_REF:0000024, GO:0045977=GO_REF:0000024, GO:0045608=GO_REF:0000019, GO:0001889=GO_REF:0000019, GO:2000227=GO_REF:0000019, GO:0043388=GO_REF:0000024, GO:0072141=GO_REF:0000019, GO:0005654=Reactome:REACT_160282, GO:0072050=GO_REF:0000019, GO:0045892=PMID:12535671, GO:0008134=PMID:17611704, GO:0035910=GO_REF:0000024, GO:0021984=GO_REF:0000019, GO:0008284=GO_REF:0000024, GO:0042668=GO_REF:0000019, GO:0042826=PMID:12535671, GO:0030324=GO_REF:0000019, GO:0007262=GO_REF:0000024, GO:0072012=GO_REF:0000019, GO:0005634=GO_REF:0000024, GO:0021537=GO_REF:0000019, GO:2000737=PMID:19682396, GO:0021575=GO_REF:0000019, GO:0030513=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0048667=GO_REF:0000019, GO:0045944=GO_REF:0000024, GO:0042102=GO_REF:0000019, GO:0090102=GO_REF:0000019, GO:0048469=GO_REF:0000019, GO:0007155=GO_REF:0000019, GO:0035019=GO_REF:0000019, GO:0003266=GO_REF:0000024, GO:0060164=GO_REF:0000019, GO:0097150=PMID:19682396, GO:0060412=GO_REF:0000024, GO:0042517=GO_REF:0000024, GO:0060253=GO_REF:0000024, GO:0003677=PMID:7906273, GO:0003151=GO_REF:0000024, GO:0007399=PMID:8020957, GO:0046427=GO_REF:0000024, GO:0043565=GO_REF:0000024, GO:0001078=GO_REF:0000024, GO:2000974=PMID:12032823, GO:0048711=GO_REF:0000024, GO:0006461=GO_REF:0000024, GO:0016477=GO_REF:0000019, GO:0061309=GO_REF:0000024, GO:0031018=Reactome:REACT_13698, GO:0048715=GO_REF:0000024, GO:0030901=GO_REF:0000019, GO:0097084=GO_REF:0000024, GO:2000978=GO_REF:0000024} Q14469 Transcription factor HES-1 protein 20120730 {GO:0005515=IPI, GO:0071820=ISS, GO:0003700=IDA, GO:0021555=IEA, GO:0061106=IEA, GO:0045598=IEA, GO:0021558=IEA, GO:0021557=IEA, GO:0046331=IEA, GO:0072282=IEA, GO:0048844=ISS, GO:0048538=ISS, GO:0003281=ISS, GO:0060675=IEA, GO:0021861=ISS, GO:0042803=ISS, GO:0007224=IEA, GO:0003143=ISS, GO:0061009=IEA, GO:0007219=TAS, GO:0060716=IEA, GO:0045747=IEA, GO:0000122=IDA, GO:0072049=IEA, GO:0060037=ISS, GO:0045977=ISS, GO:0045608=IEA, GO:0001889=IEA, GO:2000227=IEA, GO:0043388=ISS, GO:0072141=IEA, GO:0005654=TAS, GO:0072050=IEA, GO:0045892=IDA, GO:0008134=NAS, GO:0035910=ISS, GO:0021984=IEA, GO:0008284=ISS, GO:0042668=IEA, GO:0042826=IPI, GO:0030324=IEA, GO:0007262=ISS, GO:0072012=IEA, GO:0005634=ISS, GO:0021537=IEA, GO:2000737=IMP, GO:0021575=IEA, GO:0030513=IEA, GO:0005737=IEA, GO:0048667=IEA, GO:0045944=ISS, GO:0042102=IEA, GO:0090102=IEA, GO:0048469=IEA, GO:0007155=IEA, GO:0035019=IEA, GO:0003266=ISS, GO:0060164=IEA, GO:0097150=IEP, GO:0060412=ISS, GO:0042517=ISS, GO:0060253=ISS, GO:0003677=TAS, GO:0003151=ISS, GO:0007399=TAS, GO:0046427=ISS, GO:0043565=ISS, GO:0001078=ISS, GO:2000974=IMP, GO:0048711=ISS, GO:0006461=ISS, GO:0016477=IEA, GO:0061309=ISS, GO:0031018=TAS, GO:0048715=ISS, GO:0030901=IEA, GO:0097084=ISS, GO:2000978=ISS} Notch signaling pathway, S-shaped body morphogenesis, STAT protein import into nucleus, adenohypophysis development, artery morphogenesis, ascending aorta morphogenesis, auditory receptor cell fate determination, cardiac neural crest cell development involved in outflow tract morphogenesis, cell adhesion, cell maturation, cell migration, cell morphogenesis involved in neuron differentiation, cochlea development, comma-shaped body morphogenesis, common bile duct development, embryonic heart tube morphogenesis, endocrine pancreas development, forebrain radial glial cell differentiation, glomerulus vasculature development, hindbrain morphogenesis, labyrinthine layer blood vessel development, lateral inhibition, liver development, lung development, metanephric nephron tubule morphogenesis, midbrain development, midbrain-hindbrain boundary morphogenesis, negative regulation of auditory receptor cell differentiation, negative regulation of forebrain neuron differentiation, negative regulation of glial cell proliferation, negative regulation of oligodendrocyte differentiation, negative regulation of pancreatic A cell differentiation, negative regulation of pro-B cell differentiation, negative regulation of stem cell differentiation, negative regulation of stomach neuroendocrine cell differentiation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, nervous system development, neuronal stem cell maintenance, oculomotor nerve development, outflow tract morphogenesis, pharyngeal system development, positive regulation of BMP signaling pathway, positive regulation of DNA binding, positive regulation of JAK-STAT cascade, positive regulation of Notch signaling pathway, positive regulation of T cell proliferation, positive regulation of astrocyte differentiation, positive regulation of cell proliferation, positive regulation of mitotic cell cycle, embryonic, positive regulation of transcription from RNA polymerase II promoter, positive regulation of tyrosine phosphorylation of Stat3 protein, protein complex assembly, regulation of fat cell differentiation, regulation of secondary heart field cardioblast proliferation, regulation of timing of neuron differentiation, renal interstitial cell development, smoothened signaling pathway, somatic stem cell maintenance, telencephalon development, thymus development, trochlear nerve development, ureteric bud morphogenesis, vascular smooth muscle cell development, ventricular septum development, ventricular septum morphogenesis cytoplasm, nucleoplasm, nucleus DNA binding, N-box binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, histone deacetylase binding, protein binding, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human UniProtKB:Q3UZZ2 HES4 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0008134=PMID:17611704, GO:0007399=GO_REF:0000037} Q9HCC6 Transcription factor HES-4 protein 20110715 {GO:0006355=IEA, GO:0046983=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0030154=IEA, GO:0006351=IEA, GO:0008134=NAS, GO:0007399=IEA} cell differentiation, nervous system development, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, protein dimerization activity, transcription factor binding Human HES5 Reactome UniProtKB {GO:0051216=PMID:17093926, GO:0048708=GO_REF:0000024, GO:0072282=GO_REF:0000019, GO:0021861=GO_REF:0000019, GO:0007224=GO_REF:0000024, GO:0003690=GO_REF:0000019, GO:0007219=Reactome:REACT_118859, GO:0002062=GO_REF:0000024, GO:0046983=GO_REF:0000002, GO:0045747=GO_REF:0000019, GO:0000122=GO_REF:0000024, GO:0072049=GO_REF:0000019, GO:0072086=GO_REF:0000019, GO:0007420=GO_REF:0000024, GO:0072050=GO_REF:0000019, GO:0045595=GO_REF:0000024, GO:0005654=Reactome:REACT_160289, GO:0045893=GO_REF:0000024, GO:0008134=PMID:17611704, GO:0042668=GO_REF:0000019, GO:0008284=PMID:17849174, GO:0022010=GO_REF:0000024, GO:0021781=GO_REF:0000024, GO:0021537=GO_REF:0000024, GO:2000737=PMID:19682396, GO:0030513=GO_REF:0000024, GO:0050767=GO_REF:0000024, GO:2000981=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0031641=GO_REF:0000024, GO:0048469=GO_REF:0000024, GO:0043010=GO_REF:0000024, GO:0007155=GO_REF:0000024, GO:0097150=PMID:19682396, GO:0042491=GO_REF:0000024, GO:0042517=GO_REF:0000024, GO:0005575=GO_REF:0000015, GO:0048661=PMID:19855400, GO:0046427=GO_REF:0000024, GO:0048712=GO_REF:0000024, GO:0001078=GO_REF:0000024, GO:2000974=GO_REF:0000024, GO:0006461=GO_REF:0000024, GO:0045665=GO_REF:0000024, GO:0014003=GO_REF:0000024, GO:0003682=GO_REF:0000019, GO:0048715=GO_REF:0000024, GO:0021915=GO_REF:0000024, GO:2000978=GO_REF:0000019} Q5TA89 Transcription factor HES-5 protein 20130301 {GO:0051216=IDA, GO:0048708=ISS, GO:0072282=IEA, GO:0021861=IEA, GO:0007224=ISS, GO:0003690=IEA, GO:0007219=TAS, GO:0002062=ISS, GO:0046983=IEA, GO:0045747=IEA, GO:0000122=ISS, GO:0072049=IEA, GO:0072086=IEA, GO:0007420=ISS, GO:0072050=IEA, GO:0045595=ISS, GO:0005654=TAS, GO:0045893=ISS, GO:0008134=NAS, GO:0042668=IEA, GO:0008284=IMP, GO:0022010=ISS, GO:0021781=ISS, GO:0021537=ISS, GO:2000737=IMP, GO:0030513=ISS, GO:0050767=ISS, GO:2000981=IEA, GO:0045944=IEA, GO:0031641=ISS, GO:0048469=ISS, GO:0043010=ISS, GO:0007155=ISS, GO:0097150=IEP, GO:0042491=ISS, GO:0042517=ISS, GO:0005575=ND, GO:0048661=IGI, GO:0046427=ISS, GO:0048712=ISS, GO:0001078=ISS, GO:2000974=ISS, GO:0006461=ISS, GO:0045665=ISS, GO:0014003=ISS, GO:0003682=IEA, GO:0048715=ISS, GO:0021915=ISS, GO:2000978=IEA} Notch signaling pathway, S-shaped body morphogenesis, astrocyte differentiation, auditory receptor cell differentiation, auditory receptor cell fate determination, brain development, camera-type eye development, cartilage development, cell adhesion, cell maturation, central nervous system myelination, chondrocyte differentiation, comma-shaped body morphogenesis, forebrain radial glial cell differentiation, glial cell fate commitment, metanephric nephron tubule morphogenesis, negative regulation of astrocyte differentiation, negative regulation of forebrain neuron differentiation, negative regulation of inner ear receptor cell differentiation, negative regulation of neuron differentiation, negative regulation of oligodendrocyte differentiation, negative regulation of pro-B cell differentiation, negative regulation of stem cell differentiation, negative regulation of transcription from RNA polymerase II promoter, neural tube development, neuronal stem cell maintenance, oligodendrocyte development, positive regulation of BMP signaling pathway, positive regulation of JAK-STAT cascade, positive regulation of Notch signaling pathway, positive regulation of cell proliferation, positive regulation of smooth muscle cell proliferation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of tyrosine phosphorylation of Stat3 protein, protein complex assembly, regulation of cell differentiation, regulation of myelination, regulation of neurogenesis, smoothened signaling pathway, specification of loop of Henle identity, telencephalon development cellular_component, nucleoplasm RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, chromatin binding, double-stranded DNA binding, protein dimerization activity, transcription factor binding Human HES6 UniProtKB UniProtKB {GO:0003712=PMID:10851137, GO:0005667=PMID:10851137, GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000019, GO:0006357=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0003677=GO_REF:0000002, GO:0030154=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0008134=PMID:17611704, GO:0007399=GO_REF:0000019} Q96HZ4 Transcription cofactor HES-6 protein 20110715 {GO:0003712=ISS, GO:0005667=ISS, GO:0006355=NAS, GO:0003700=IEA, GO:0006357=IEA, GO:0046983=IEA, GO:0003677=IEA, GO:0030154=IEA, GO:0006351=IEA, GO:0008134=NAS, GO:0007399=IEA} cell differentiation, nervous system development, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription, DNA-dependent transcription factor complex DNA binding, protein dimerization activity, sequence-specific DNA binding transcription factor activity, transcription cofactor activity, transcription factor binding Human HES7 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0001756=GO_REF:0000019, GO:0005634=PMID:11260262, GO:0007275=GO_REF:0000037, GO:0000122=GO_REF:0000019, GO:0003677=PMID:11260262, GO:0006351=GO_REF:0000037, GO:0036342=GO_REF:0000019, GO:0001501=GO_REF:0000019, GO:0007219=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0007498=PMID:11260262, GO:0048511=GO_REF:0000019, GO:0008134=PMID:17611704} Q9BYE0 Transcription factor HES-7 protein 20110715 {GO:0006355=IEA, GO:0001756=IEA, GO:0005634=NAS, GO:0007275=IEA, GO:0000122=IEA, GO:0003677=NAS, GO:0006351=IEA, GO:0036342=IEA, GO:0001501=IEA, GO:0007219=IEA, GO:0046983=IEA, GO:0007498=NAS, GO:0048511=IEA, GO:0008134=NAS} Notch signaling pathway, mesoderm development, multicellular organismal development, negative regulation of transcription from RNA polymerase II promoter, post-anal tail morphogenesis, regulation of transcription, DNA-dependent, rhythmic process, skeletal system development, somitogenesis, transcription, DNA-dependent nucleus DNA binding, protein dimerization activity, transcription factor binding Human HESX1 PINC UniProtKB {GO:0003700=GO_REF:0000002, GO:0030916=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0008022=GO_REF:0000019, GO:0003677=PMID:9620767, GO:0048853=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0047485=GO_REF:0000019, GO:0007420=PMID:9620767, GO:0003682=GO_REF:0000019, GO:0045892=GO_REF:0000019, GO:0043584=GO_REF:0000019} Q9UBX0 Homeobox expressed in ES cells 1 protein 20030904 {GO:0003700=IEA, GO:0030916=IEA, GO:0005634=IEA, GO:0008022=IEA, GO:0003677=TAS, GO:0048853=IEA, GO:0006351=IEA, GO:0043565=IEA, GO:0047485=IEA, GO:0007420=TAS, GO:0003682=IEA, GO:0045892=IEA, GO:0043584=IEA} brain development, forebrain morphogenesis, negative regulation of transcription, DNA-dependent, nose development, otic vesicle formation, transcription, DNA-dependent nucleus DNA binding, chromatin binding, protein C-terminus binding, protein N-terminus binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human HEXA Reactome UniProtKB {GO:0008219=GO_REF:0000037, GO:0019915=GO_REF:0000019, GO:0007605=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0005764=GO_REF:0000019, GO:0004553=GO_REF:0000002, GO:0030207=Reactome:REACT_120888, GO:0048667=GO_REF:0000019, GO:0050884=GO_REF:0000019, GO:0007628=GO_REF:0000019, GO:0050885=GO_REF:0000019, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121315, GO:0043202=Reactome:REACT_121316, GO:0004563=GO_REF:0000003, GO:0006665=Reactome:REACT_19323, GO:0046982=PMID:6230359, GO:0006687=Reactome:REACT_116105, GO:0005975=Reactome:REACT_474, GO:0006689=GO_REF:0000019, GO:0042552=GO_REF:0000019, GO:0042339=Reactome:REACT_121288, GO:0019953=GO_REF:0000019, GO:0001501=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0042340=Reactome:REACT_121313, GO:0030212=Reactome:REACT_121083, GO:0030214=Reactome:REACT_120996, GO:0007040=GO_REF:0000019} P06865 Beta-hexosaminidase subunit alpha protein 20110921 {GO:0008219=IEA, GO:0019915=IEA, GO:0007605=IEA, GO:0044281=TAS, GO:0005764=IEA, GO:0004553=IEA, GO:0030207=TAS, GO:0048667=IEA, GO:0050884=IEA, GO:0007628=IEA, GO:0050885=IEA, GO:0030204=TAS, GO:0030203=TAS, GO:0043202=TAS, GO:0004563=IEA, GO:0006665=TAS, GO:0046982=IDA, GO:0006687=TAS, GO:0005975=TAS, GO:0006689=IEA, GO:0042552=IEA, GO:0042339=TAS, GO:0019953=IEA, GO:0001501=IEA, GO:0016020=IEA, GO:0042340=TAS, GO:0030212=TAS, GO:0030214=TAS, GO:0007040=IEA} adult walking behavior, carbohydrate metabolic process, cell death, cell morphogenesis involved in neuron differentiation, chondroitin sulfate catabolic process, chondroitin sulfate metabolic process, ganglioside catabolic process, glycosaminoglycan metabolic process, glycosphingolipid metabolic process, hyaluronan catabolic process, hyaluronan metabolic process, keratan sulfate catabolic process, keratan sulfate metabolic process, lipid storage, lysosome organization, myelination, neuromuscular process controlling balance, neuromuscular process controlling posture, sensory perception of sound, sexual reproduction, skeletal system development, small molecule metabolic process, sphingolipid metabolic process lysosomal lumen, lysosome, membrane beta-N-acetylhexosaminidase activity, hydrolase activity, hydrolyzing O-glycosyl compounds, protein heterodimerization activity Human HEXB ENSEMBL UniProtKB {GO:0008219=GO_REF:0000037, GO:0048477=GO_REF:0000019, GO:0019915=GO_REF:0000019, GO:0008360=GO_REF:0000019, GO:0007605=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0005764=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0004553=GO_REF:0000002, GO:0030207=Reactome:REACT_120888, GO:0045944=GO_REF:0000019, GO:0050885=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0030204=Reactome:REACT_121206, GO:0030203=GO_REF:0000019, GO:0043202=Reactome:REACT_121316, GO:0006665=Reactome:REACT_19323, GO:0004563=GO_REF:0000019, GO:0009313=GO_REF:0000019, GO:0006687=Reactome:REACT_116105, GO:0046982=PMID:6230359, GO:0001669=GO_REF:0000019, GO:0005975=Reactome:REACT_474, GO:0006689=GO_REF:0000019, GO:0042552=GO_REF:0000019, GO:0006874=GO_REF:0000019, GO:0008654=GO_REF:0000019, GO:0043615=GO_REF:0000019, GO:0042339=Reactome:REACT_121288, GO:0001501=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0042340=Reactome:REACT_121313, GO:0030212=Reactome:REACT_121083, GO:0007341=GO_REF:0000019, GO:0030214=Reactome:REACT_120996, GO:0007040=GO_REF:0000019, GO:0044267=GO_REF:0000019, GO:0008049=GO_REF:0000019} Q5URX0 Beta-hexosaminidase subunit beta protein 20130413 {GO:0008219=IEA, GO:0048477=IEA, GO:0019915=IEA, GO:0008360=IEA, GO:0007605=IEA, GO:0044281=TAS, GO:0003824=IEA, GO:0005764=IEA, GO:0042803=IEA, GO:0004553=IEA, GO:0030207=TAS, GO:0045944=IEA, GO:0050885=IEA, GO:0007626=IEA, GO:0030204=TAS, GO:0030203=IEA, GO:0043202=TAS, GO:0006665=TAS, GO:0004563=IEA, GO:0009313=IEA, GO:0006687=TAS, GO:0046982=IDA, GO:0001669=IEA, GO:0005975=TAS, GO:0006689=IEA, GO:0042552=IEA, GO:0006874=IEA, GO:0008654=IEA, GO:0043615=IEA, GO:0042339=TAS, GO:0001501=IEA, GO:0016020=IEA, GO:0042340=TAS, GO:0030212=TAS, GO:0007341=IEA, GO:0030214=TAS, GO:0007040=IEA, GO:0044267=IEA, GO:0008049=IEA} astrocyte cell migration, carbohydrate metabolic process, cell death, cellular calcium ion homeostasis, cellular protein metabolic process, chondroitin sulfate catabolic process, chondroitin sulfate metabolic process, ganglioside catabolic process, glycosaminoglycan metabolic process, glycosphingolipid metabolic process, hyaluronan catabolic process, hyaluronan metabolic process, keratan sulfate catabolic process, keratan sulfate metabolic process, lipid storage, locomotory behavior, lysosome organization, male courtship behavior, myelination, neuromuscular process controlling balance, oligosaccharide catabolic process, oogenesis, penetration of zona pellucida, phospholipid biosynthetic process, positive regulation of transcription from RNA polymerase II promoter, regulation of cell shape, sensory perception of sound, skeletal system development, small molecule metabolic process, sphingolipid metabolic process acrosomal vesicle, lysosomal lumen, lysosome, membrane beta-N-acetylhexosaminidase activity, catalytic activity, hydrolase activity, hydrolyzing O-glycosyl compounds, protein heterodimerization activity, protein homodimerization activity Human Ensembl:ENSMUSP00000022169 HEXDC UniProtKB UniProtKB {GO:0004563=GO_REF:0000003, GO:0005737=GO_REF:0000039, GO:0005975=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003824=GO_REF:0000002, GO:0004553=GO_REF:0000002} Q8WVB3 Hexosaminidase D protein 20130413 {GO:0004563=IEA, GO:0005737=IEA, GO:0005975=IEA, GO:0005634=IEA, GO:0003824=IEA, GO:0004553=IEA} carbohydrate metabolic process cytoplasm, nucleus beta-N-acetylhexosaminidase activity, catalytic activity, hydrolase activity, hydrolyzing O-glycosyl compounds Human UniProtKB-SubCell:SL-0086 HEXIM1 HPA UniProtKB {GO:0005515=PMID:15941832, GO:0007507=GO_REF:0000019, GO:0005737=PMID:12581153, GO:0045736=PMID:14580347, GO:0005730=GO_REF:0000052, GO:0004861=PMID:14580347, GO:0017069=PMID:14580347, GO:0005634=GO_REF:0000052, GO:0000122=PMID:14580347, GO:0045892=PMID:14580347, GO:0006351=GO_REF:0000037} O94992 Protein HEXIM1 protein 20101115 {GO:0005515=IPI, GO:0007507=IEA, GO:0005737=IDA, GO:0045736=IDA, GO:0005730=IDA, GO:0004861=IDA, GO:0017069=IDA, GO:0005634=IDA, GO:0000122=IDA, GO:0045892=IDA, GO:0006351=IEA} heart development, negative regulation of cyclin-dependent protein serine/threonine kinase activity, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleolus, nucleus cyclin-dependent protein serine/threonine kinase inhibitor activity, protein binding, snRNA binding NOT Human HEXIM2 HPA UniProtKB {GO:0005515=PMID:15713661, GO:0005737=GO_REF:0000052, GO:0045736=PMID:15713662, GO:0005730=GO_REF:0000052, GO:0004861=PMID:15713662, GO:0017069=PMID:15713662, GO:0005634=GO_REF:0000052, GO:0000122=PMID:15713662, GO:0045892=PMID:15713662, GO:0006351=GO_REF:0000037} Q96MH2 Protein HEXIM2 protein 20100326 {GO:0005515=IPI, GO:0005737=IDA, GO:0045736=IDA, GO:0005730=IDA, GO:0004861=IDA, GO:0017069=IDA, GO:0005634=IDA, GO:0000122=IDA, GO:0045892=IDA, GO:0006351=IEA} negative regulation of cyclin-dependent protein serine/threonine kinase activity, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleolus, nucleus cyclin-dependent protein serine/threonine kinase inhibitor activity, protein binding, snRNA binding Human HEY1 BHF-UCL UniProtKB {GO:0005515=PMID:10692439, GO:0000988=PMID:21290414, GO:2001212=GO_REF:0000024, GO:0035912=GO_REF:0000024, GO:0003700=PMID:15485867, GO:0000983=GO_REF:0000024, GO:0003184=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:2000678=PMID:18239137, GO:0060317=GO_REF:0000024, GO:0061314=PMID:17259303, GO:0005737=GO_REF:0000024, GO:0007219=Reactome:REACT_118859, GO:0009948=GO_REF:0000019, GO:0045944=GO_REF:0000024, GO:0003222=GO_REF:0000019, GO:0060716=GO_REF:0000024, GO:0046983=GO_REF:0000002, GO:2000820=PMID:18239137, GO:0045746=PMID:18239137, GO:0006355=GO_REF:0000038, GO:0003199=GO_REF:0000019, GO:0003198=GO_REF:0000024, GO:0060412=GO_REF:0000024, GO:0060411=GO_REF:0000024, GO:0003203=GO_REF:0000024, GO:0060842=GO_REF:0000024, GO:0000122=PMID:11486045, GO:0001525=PMID:11866539, GO:0003208=GO_REF:0000024, GO:0003190=GO_REF:0000024, GO:0035939=PMID:21290414, GO:0036304=GO_REF:0000024, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000038, GO:0060347=GO_REF:0000024, GO:0045669=GO_REF:0000019, GO:0002076=GO_REF:0000019, GO:0005654=Reactome:REACT_160290, GO:0001570=GO_REF:0000019, GO:0045892=PMID:15485867, GO:0008134=PMID:17611704} Q9Y5J3 Hairy/enhancer-of-split related with YRPW motif protein 1 protein 20110615 {GO:0005515=IPI, GO:0000988=IDA, GO:2001212=ISS, GO:0035912=ISS, GO:0003700=IDA, GO:0000983=ISS, GO:0003184=ISS, GO:0005634=ISS, GO:2000678=IDA, GO:0060317=ISS, GO:0061314=IC, GO:0005737=ISS, GO:0007219=TAS, GO:0009948=IEA, GO:0045944=ISS, GO:0003222=IEA, GO:0060716=ISS, GO:0046983=IEA, GO:2000820=IDA, GO:0045746=IDA, GO:0006355=IEA, GO:0003199=IEA, GO:0003198=ISS, GO:0060412=ISS, GO:0060411=ISS, GO:0003203=ISS, GO:0060842=ISS, GO:0000122=IMP, GO:0001525=IEP, GO:0003208=ISS, GO:0003190=ISS, GO:0035939=IDA, GO:0036304=ISS, GO:0003677=IEA, GO:0006351=IEA, GO:0060347=ISS, GO:0045669=IEA, GO:0002076=IEA, GO:0005654=TAS, GO:0001570=IEA, GO:0045892=IDA, GO:0008134=NAS} Notch signaling involved in heart development, Notch signaling pathway, angiogenesis, anterior/posterior axis specification, arterial endothelial cell differentiation, atrioventricular valve formation, cardiac epithelial to mesenchymal transition, cardiac septum morphogenesis, cardiac ventricle morphogenesis, dorsal aorta morphogenesis, endocardial cushion morphogenesis, endocardial cushion to mesenchymal transition involved in heart valve formation, epithelial to mesenchymal transition involved in endocardial cushion formation, heart trabecula formation, labyrinthine layer blood vessel development, negative regulation of Notch signaling pathway, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation, negative regulation of transcription regulatory region DNA binding, negative regulation of transcription, DNA-dependent, osteoblast development, positive regulation of osteoblast differentiation, positive regulation of transcription from RNA polymerase II promoter, pulmonary valve morphogenesis, regulation of transcription, DNA-dependent, regulation of vasculogenesis, transcription, DNA-dependent, umbilical cord morphogenesis, vasculogenesis, ventricular septum morphogenesis, ventricular trabecula myocardium morphogenesis cytoplasm, nucleoplasm, nucleus DNA binding, RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity, microsatellite binding, protein binding, protein binding transcription factor activity, protein dimerization activity, sequence-specific DNA binding transcription factor activity, transcription factor binding Human HEY2 BHF-UCL UniProtKB {GO:0005515=PMID:11486045, GO:0060045=GO_REF:0000019, GO:0000988=PMID:21290414, GO:2001212=GO_REF:0000024, GO:0003700=PMID:15485867, GO:0000983=GO_REF:0000024, GO:0003184=GO_REF:0000024, GO:0003186=GO_REF:0000024, GO:0007219=Reactome:REACT_118859, GO:0016580=PMID:11486045, GO:0017053=PMID:11486045, GO:0014031=GO_REF:0000024, GO:0046983=GO_REF:0000002, GO:0060716=GO_REF:0000024, GO:0010667=GO_REF:0000019, GO:2000820=GO_REF:0000024, GO:0001102=PMID:16293227, GO:0045746=GO_REF:0000019, GO:0003171=GO_REF:0000019, GO:2000723=GO_REF:0000024, GO:0000122=PMID:16293227, GO:0065004=GO_REF:0000019, GO:0060347=GO_REF:0000019, GO:0060633=PMID:10692439, GO:0045607=GO_REF:0000019, GO:0045165=GO_REF:0000019, GO:0061156=GO_REF:0000024, GO:0055015=GO_REF:0000024, GO:0005654=Reactome:REACT_160290, GO:0010460=GO_REF:0000019, GO:0045892=PMID:12535671, GO:0051145=PMID:10692439, GO:0008134=PMID:17611704, GO:0035910=GO_REF:0000024, GO:0035912=GO_REF:0000024, GO:0042826=PMID:12535671, GO:0005634=GO_REF:0000024, GO:0003215=GO_REF:0000024, GO:0003214=GO_REF:0000024, GO:2000678=PMID:10692439, GO:0060977=GO_REF:0000019, GO:0060317=GO_REF:0000024, GO:0061314=PMID:12372254, GO:0005737=GO_REF:0000024, GO:0009948=GO_REF:0000019, GO:0045944=GO_REF:0000024, GO:0014898=GO_REF:0000019, GO:0003222=GO_REF:0000019, GO:0090102=GO_REF:0000019, GO:0003150=GO_REF:0000024, GO:0003199=GO_REF:0000019, GO:0060413=GO_REF:0000024, GO:0060412=GO_REF:0000024, GO:0060411=GO_REF:0000024, GO:0003195=GO_REF:0000019, GO:0060842=GO_REF:0000024, GO:0036304=GO_REF:0000024, GO:0035939=PMID:21290414, GO:0003208=GO_REF:0000024, GO:0003151=GO_REF:0000024, GO:0043565=PMID:11486045, GO:0060948=GO_REF:0000019, GO:0010629=GO_REF:0000024, GO:0097084=PMID:15821257, GO:0001570=GO_REF:0000019, GO:0010621=GO_REF:0000024} Q9UBP5 Hairy/enhancer-of-split related with YRPW motif protein 2 protein 20110615 {GO:0005515=IPI, GO:0060045=IEA, GO:0000988=IDA, GO:2001212=ISS, GO:0003700=IDA, GO:0000983=ISS, GO:0003184=ISS, GO:0003186=ISS, GO:0007219=TAS, GO:0016580=IDA, GO:0017053=IDA, GO:0014031=ISS, GO:0046983=IEA, GO:0060716=ISS, GO:0010667=IEA, GO:2000820=ISS, GO:0001102=IPI, GO:0045746=IEA, GO:0003171=IEA, GO:2000723=ISS, GO:0000122=IDA, GO:0065004=IEA, GO:0060347=IEA, GO:0060633=IDA, GO:0045607=IEA, GO:0045165=IEA, GO:0061156=ISS, GO:0055015=ISS, GO:0005654=TAS, GO:0010460=IEA, GO:0045892=IDA, GO:0051145=NAS, GO:0008134=NAS, GO:0035910=ISS, GO:0035912=ISS, GO:0042826=IPI, GO:0005634=ISS, GO:0003215=ISS, GO:0003214=ISS, GO:2000678=IDA, GO:0060977=IEA, GO:0060317=ISS, GO:0061314=IC, GO:0005737=ISS, GO:0009948=IEA, GO:0045944=ISS, GO:0014898=IEA, GO:0003222=IEA, GO:0090102=IEA, GO:0003150=ISS, GO:0003199=IEA, GO:0060413=ISS, GO:0060412=ISS, GO:0060411=ISS, GO:0003195=IEA, GO:0060842=ISS, GO:0036304=ISS, GO:0035939=IDA, GO:0003208=ISS, GO:0003151=ISS, GO:0043565=IDA, GO:0060948=IEA, GO:0010629=ISS, GO:0097084=IEP, GO:0001570=IEA, GO:0010621=ISS} Notch signaling involved in heart development, Notch signaling pathway, anterior/posterior axis specification, arterial endothelial cell differentiation, ascending aorta morphogenesis, atrial septum morphogenesis, atrioventricular valve development, cardiac epithelial to mesenchymal transition, cardiac left ventricle morphogenesis, cardiac muscle hypertrophy in response to stress, cardiac right ventricle morphogenesis, cardiac septum morphogenesis, cardiac vascular smooth muscle cell development, cardiac ventricle morphogenesis, cell fate commitment, cochlea development, coronary vasculature morphogenesis, dorsal aorta morphogenesis, endocardial cushion to mesenchymal transition involved in heart valve formation, heart trabecula formation, labyrinthine layer blood vessel development, mesenchymal cell development, muscular septum morphogenesis, negative regulation of Notch signaling pathway, negative regulation of cardiac muscle cell apoptotic process, negative regulation of cardiac vascular smooth muscle cell differentiation, negative regulation of gene expression, negative regulation of transcription by transcription factor localization, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation, negative regulation of transcription initiation from RNA polymerase II promoter, negative regulation of transcription regulatory region DNA binding, negative regulation of transcription, DNA-dependent, outflow tract morphogenesis, positive regulation of cardiac muscle cell proliferation, positive regulation of heart rate, positive regulation of transcription from RNA polymerase II promoter, protein-DNA complex assembly, pulmonary artery morphogenesis, pulmonary valve morphogenesis, regulation of auditory receptor cell differentiation, regulation of vasculogenesis, smooth muscle cell differentiation, tricuspid valve formation, tricuspid valve morphogenesis, umbilical cord morphogenesis, vascular smooth muscle cell development, vasculogenesis, ventricular cardiac muscle cell development, ventricular septum morphogenesis, ventricular trabecula myocardium morphogenesis Sin3 complex, cytoplasm, nucleoplasm, nucleus, transcriptional repressor complex RNA polymerase II activating transcription factor binding, RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity, histone deacetylase binding, microsatellite binding, protein binding, protein binding transcription factor activity, protein dimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human UniProtKB:Q61169 HEYL BHF-UCL UniProtKB {GO:0071773=GO_REF:0000019, GO:0005515=PMID:21454491, GO:0000988=PMID:21290414, GO:0003700=PMID:15485867, GO:0000983=GO_REF:0000024, GO:0003181=GO_REF:0000024, GO:0072014=GO_REF:0000019, GO:0003184=GO_REF:0000024, GO:0005634=PMID:21454491, GO:0050683=PMID:21454491, GO:0042803=GO_REF:0000019, GO:0032835=GO_REF:0000019, GO:0060317=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0007219=Reactome:REACT_118859, GO:0045944=PMID:21290414, GO:0014031=GO_REF:0000024, GO:0046982=PMID:21454491, GO:0003198=GO_REF:0000024, GO:0001106=GO_REF:0000019, GO:0003714=PMID:21454491, GO:0060412=GO_REF:0000024, GO:0003203=GO_REF:0000024, GO:0060766=PMID:21454491, GO:0003208=GO_REF:0000024, GO:2000824=PMID:21454491, GO:0035939=PMID:21290414, GO:0000979=GO_REF:0000019, GO:0003151=GO_REF:0000024, GO:0001077=GO_REF:0000019, GO:0045666=GO_REF:0000024, GO:0005654=Reactome:REACT_160290, GO:0045892=PMID:21454491, GO:0008134=PMID:17611704} Q9NQ87 Hairy/enhancer-of-split related with YRPW motif-like protein protein 20120730 {GO:0071773=IEA, GO:0005515=IPI, GO:0000988=IDA, GO:0003700=IDA, GO:0000983=ISS, GO:0003181=ISS, GO:0072014=IEA, GO:0003184=ISS, GO:0005634=IDA, GO:0050683=IPI, GO:0042803=IEA, GO:0032835=IEA, GO:0060317=ISS, GO:0005737=ISS, GO:0007219=TAS, GO:0045944=IDA, GO:0014031=ISS, GO:0046982=IDA, GO:0003198=ISS, GO:0001106=IEA, GO:0003714=IDA, GO:0060412=ISS, GO:0003203=ISS, GO:0060766=IDA, GO:0003208=ISS, GO:2000824=IDA, GO:0035939=IDA, GO:0000979=IEA, GO:0003151=ISS, GO:0001077=IEA, GO:0045666=ISS, GO:0005654=TAS, GO:0045892=IDA, GO:0008134=NAS} Notch signaling pathway, atrioventricular valve morphogenesis, cardiac epithelial to mesenchymal transition, cardiac ventricle morphogenesis, cellular response to BMP stimulus, endocardial cushion morphogenesis, epithelial to mesenchymal transition involved in endocardial cushion formation, glomerulus development, mesenchymal cell development, negative regulation of androgen receptor activity, negative regulation of androgen receptor signaling pathway, negative regulation of transcription, DNA-dependent, outflow tract morphogenesis, positive regulation of neuron differentiation, positive regulation of transcription from RNA polymerase II promoter, proximal tubule development, pulmonary valve morphogenesis, ventricular septum morphogenesis cytoplasm, nucleoplasm, nucleus AF-1 domain binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II core promoter sequence-specific DNA binding, RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity, RNA polymerase II transcription corepressor activity, microsatellite binding, protein binding, protein binding transcription factor activity, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding transcription factor activity, transcription corepressor activity, transcription factor binding Human UniProtKB:Q9DBX7 HFE InterPro UniProtKB {GO:0005515=PMID:15880641, GO:0002474=GO_REF:0000037, GO:0007565=GO_REF:0000019, GO:0048471=PMID:15880641, GO:0005886=PMID:10638746, GO:0042612=GO_REF:0000002, GO:0005102=PMID:10638746, GO:0045178=PMID:15880641, GO:0010106=GO_REF:0000019, GO:0045177=PMID:15880641, GO:0031410=PMID:15880641, GO:0060586=GO_REF:0000019, GO:0006879=PMID:10638746, GO:0006955=GO_REF:0000002, GO:0006461=PMID:10638746, GO:0005887=PMID:10638746, GO:0019882=GO_REF:0000002, GO:0042446=GO_REF:0000019, GO:0055037=PMID:15880641, GO:0005769=PMID:15880641} Q6B0J5 HFE protein protein 20130413 {GO:0005515=IPI, GO:0002474=IEA, GO:0007565=IEA, GO:0048471=IDA, GO:0005886=TAS, GO:0042612=IEA, GO:0005102=IPI, GO:0045178=IDA, GO:0010106=IEA, GO:0045177=IDA, GO:0031410=IDA, GO:0060586=IEA, GO:0006879=TAS, GO:0006955=IEA, GO:0006461=TAS, GO:0005887=TAS, GO:0019882=IEA, GO:0042446=IEA, GO:0055037=IDA, GO:0005769=IDA} antigen processing and presentation, antigen processing and presentation of peptide antigen via MHC class I, cellular iron ion homeostasis, cellular response to iron ion starvation, female pregnancy, hormone biosynthetic process, immune response, multicellular organismal iron ion homeostasis, protein complex assembly MHC class I protein complex, apical part of cell, basal part of cell, cytoplasmic vesicle, early endosome, integral to plasma membrane, perinuclear region of cytoplasm, plasma membrane, recycling endosome protein binding, receptor binding Human InterPro:IPR001039 HFE2 Reactome UniProtKB {GO:0005515=PMID:19357398, GO:0005886=PMID:16075058, GO:0009986=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0045944=GO_REF:0000019, GO:0031225=GO_REF:0000037, GO:0030509=GO_REF:0000019, GO:0015026=GO_REF:0000019, GO:0055072=PMID:16075058, GO:0005615=GO_REF:0000019} Q6ZVN8 Hemojuvelin protein 20130301 {GO:0005515=IPI, GO:0005886=IDA, GO:0009986=IEA, GO:0007411=TAS, GO:0045944=IEA, GO:0031225=IEA, GO:0030509=IEA, GO:0015026=IEA, GO:0055072=IGI, GO:0005615=IEA} BMP signaling pathway, axon guidance, iron ion homeostasis, positive regulation of transcription from RNA polymerase II promoter anchored to membrane, cell surface, extracellular space, plasma membrane coreceptor activity, protein binding Human HGD Reactome UniProtKB {GO:0034641=Reactome:REACT_13, GO:0006559=Reactome:REACT_1786, GO:0004411=Reactome:REACT_557, GO:0006570=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0006572=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_557} Q93099 Homogentisate 1,2-dioxygenase protein 20130213 {GO:0034641=TAS, GO:0006559=TAS, GO:0004411=EXP, GO:0006570=IEA, GO:0044281=TAS, GO:0006572=IEA, GO:0046872=IEA, GO:0005829=TAS} L-phenylalanine catabolic process, cellular nitrogen compound metabolic process, small molecule metabolic process, tyrosine catabolic process, tyrosine metabolic process cytosol homogentisate 1,2-dioxygenase activity, metal ion binding Human HGF GOC UniProtKB {GO:0005515=PMID:18585357, GO:0004252=PMID:2531289, GO:2000573=PMID:2531289, GO:0031100=GO_REF:0000019, GO:0050731=PMID:21245381, GO:0001837=PMID:14679171, GO:0005615=GO_REF:0000019, GO:0000187=GO_REF:0000019, GO:0090201=PMID:20655899, GO:0060665=PMID:14517989, GO:0045944=PMID:22521434, GO:0035729=PMID:21245381, GO:0006508=PMID:2531289, GO:0031093=Reactome:REACT_21351, GO:0043066=GO_REF:0000019, GO:0030335=PMID:21245381, GO:0048012=PMID:21245381, GO:0046982=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0014068=PMID:20655899, GO:0005576=Reactome:REACT_21351, GO:0042056=PMID:21245381, GO:0050918=PMID:21245381, GO:0045669=PMID:22521434, GO:0001889=GO_REF:0000019, GO:0000902=GO_REF:0000019, GO:0007067=PMID:2531289, GO:0007596=Reactome:REACT_604, GO:0060326=PMID:21245381, GO:0002576=Reactome:REACT_318, GO:0051450=GO_REF:0000019, GO:0008083=PMID:2531289} P14210 Hepatocyte growth factor protein 20130413 {GO:0005515=IPI, GO:0004252=NAS, GO:2000573=IDA, GO:0031100=IEA, GO:0050731=IDA, GO:0001837=TAS, GO:0005615=IEA, GO:0000187=IEA, GO:0090201=IDA, GO:0060665=IDA, GO:0045944=NAS, GO:0035729=IDA, GO:0006508=NAS, GO:0031093=TAS, GO:0043066=IEA, GO:0030335=IDA, GO:0048012=IDA, GO:0046982=IEA, GO:0030168=TAS, GO:0014068=IDA, GO:0005576=TAS, GO:0042056=IDA, GO:0050918=IDA, GO:0045669=NAS, GO:0001889=IEA, GO:0000902=IEA, GO:0007067=NAS, GO:0007596=TAS, GO:0060326=IDA, GO:0002576=TAS, GO:0051450=IEA, GO:0008083=NAS} activation of MAPK activity, blood coagulation, cell chemotaxis, cell morphogenesis, cellular response to hepatocyte growth factor stimulus, epithelial to mesenchymal transition, hepatocyte growth factor receptor signaling pathway, liver development, mitosis, myoblast proliferation, negative regulation of apoptotic process, negative regulation of release of cytochrome c from mitochondria, organ regeneration, platelet activation, platelet degranulation, positive chemotaxis, positive regulation of DNA biosynthetic process, positive regulation of cell migration, positive regulation of osteoblast differentiation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of transcription from RNA polymerase II promoter, proteolysis, regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling extracellular region, extracellular space, platelet alpha granule lumen chemoattractant activity, growth factor activity, protein binding, protein heterodimerization activity, serine-type endopeptidase activity Human HGFAC PINC UniProtKB {GO:0005791=GO_REF:0000019, GO:0004252=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0008236=PMID:8226803, GO:0005576=PMID:14718574, GO:0005615=GO_REF:0000002} Q04756 Hepatocyte growth factor activator protein 20030904 {GO:0005791=IEA, GO:0004252=IEA, GO:0006508=IEA, GO:0008236=TAS, GO:0005576=NAS, GO:0005615=IEA} proteolysis extracellular region, extracellular space, rough endoplasmic reticulum serine-type endopeptidase activity, serine-type peptidase activity Human HGS HPA UniProtKB {GO:0005515=PMID:10861283, GO:0008285=PMID:9407053, GO:0042176=PMID:15611048, GO:0008333=GO_REF:0000019, GO:0019904=PMID:11984006, GO:0042059=Reactome:REACT_12484, GO:0032585=GO_REF:0000039, GO:0009966=GO_REF:0000002, GO:0006886=GO_REF:0000002, GO:0046426=PMID:12444102, GO:0046872=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0005829=Reactome:REACT_27272, GO:0007165=PMID:9407053, GO:0005737=GO_REF:0000052, GO:0007173=Reactome:REACT_9417, GO:0016020=GO_REF:0000019, GO:0031901=GO_REF:0000039, GO:0016197=Reactome:REACT_27258, GO:0030141=GO_REF:0000019, GO:0005769=PMID:10861283, GO:0016044=Reactome:REACT_11123, GO:0005768=PMID:15611048} O14964 Hepatocyte growth factor-regulated tyrosine kinase substrate protein 20080818 {GO:0005515=IPI, GO:0008285=TAS, GO:0042176=TAS, GO:0008333=IEA, GO:0019904=IPI, GO:0042059=TAS, GO:0032585=IEA, GO:0009966=IEA, GO:0006886=IEA, GO:0046426=IDA, GO:0046872=IEA, GO:0043231=IDA, GO:0005829=TAS, GO:0007165=TAS, GO:0005737=IDA, GO:0007173=TAS, GO:0016020=IEA, GO:0031901=IEA, GO:0016197=TAS, GO:0030141=IEA, GO:0005769=IDA, GO:0016044=TAS, GO:0005768=IDA} cellular membrane organization, endosomal transport, endosome to lysosome transport, epidermal growth factor receptor signaling pathway, intracellular protein transport, negative regulation of JAK-STAT cascade, negative regulation of cell proliferation, negative regulation of epidermal growth factor receptor signaling pathway, regulation of protein catabolic process, regulation of signal transduction, signal transduction cytoplasm, cytosol, early endosome, early endosome membrane, endosome, intracellular membrane-bounded organelle, membrane, multivesicular body membrane, secretory granule metal ion binding, protein binding, protein domain specific binding Human HHAT UniProtKB UniProtKB {GO:0018345=GO_REF:0000019, GO:0016746=GO_REF:0000037, GO:0005789=GO_REF:0000039, GO:0016409=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005525=GO_REF:0000037, GO:0016740=GO_REF:0000038, GO:0007224=GO_REF:0000019} Q5VTY9 Protein-cysteine N-palmitoyltransferase HHAT protein 20130413 {GO:0018345=IEA, GO:0016746=IEA, GO:0005789=IEA, GO:0016409=IEA, GO:0007275=IEA, GO:0016021=IEA, GO:0005525=IEA, GO:0016740=IEA, GO:0007224=IEA} multicellular organismal development, protein palmitoylation, smoothened signaling pathway endoplasmic reticulum membrane, integral to membrane GTP binding, palmitoyltransferase activity, transferase activity, transferase activity, transferring acyl groups Human UniProtKB-SubCell:SL-0097 HHATL UniProtKB UniProtKB {GO:0048471=PMID:11374908, GO:0005783=GO_REF:0000024, GO:0005789=GO_REF:0000039, GO:0060262=GO_REF:0000024, GO:0016021=GO_REF:0000037} Q9HCP6 Protein-cysteine N-palmitoyltransferase HHAT-like protein protein 20110201 {GO:0048471=IDA, GO:0005783=ISS, GO:0005789=IEA, GO:0060262=ISS, GO:0016021=IEA} negative regulation of N-terminal protein palmitoylation endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, perinuclear region of cytoplasm Human HHEX BHF-UCL UniProtKB {GO:0005515=PMID:19324893, GO:0034504=PMID:18713067, GO:0003700=GO_REF:0000002, GO:0044212=PMID:18755198, GO:0030878=GO_REF:0000019, GO:0030154=PMID:10871399, GO:0042803=PMID:16540119, GO:0060431=GO_REF:0000019, GO:0010944=PMID:19324893, GO:0006406=PMID:12554669, GO:0032993=PMID:18755198, GO:0061009=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0022027=GO_REF:0000019, GO:0016055=GO_REF:0000037, GO:0071103=PMID:18755198, GO:0008301=PMID:18755198, GO:0000122=PMID:15016828, GO:0001701=GO_REF:0000019, GO:0002573=GO_REF:0000019, GO:0007049=PMID:12554669, GO:0061017=GO_REF:0000019, GO:0016973=PMID:12554669, GO:0061010=GO_REF:0000019, GO:0017025=PMID:19324893, GO:0061011=GO_REF:0000019, GO:0071837=GO_REF:0000019, GO:0045892=PMID:15016828, GO:0008134=PMID:15016828, GO:0030948=PMID:15016828, GO:0008283=PMID:12554669, GO:0043434=GO_REF:0000019, GO:0030177=GO_REF:0000024, GO:0005634=PMID:12588764, GO:0009952=GO_REF:0000024, GO:0005737=PMID:12554669, GO:0035264=GO_REF:0000019, GO:0048568=GO_REF:0000019, GO:0045944=PMID:12655000, GO:0030183=GO_REF:0000024, GO:0070491=PMID:15187083, GO:0035050=GO_REF:0000019, GO:0090009=GO_REF:0000019, GO:0009611=GO_REF:0000019, GO:0048853=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0043565=PMID:10871399, GO:0007165=GO_REF:0000019, GO:0007492=GO_REF:0000019, GO:0031016=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0016525=PMID:15016828, GO:0008190=PMID:12554669, GO:0001570=GO_REF:0000019, GO:0010621=PMID:18713067, GO:0070365=GO_REF:0000019} Q03014 Hematopoietically-expressed homeobox protein HHEX protein 20100218 {GO:0005515=IPI, GO:0034504=IDA, GO:0003700=IEA, GO:0044212=IDA, GO:0030878=IEA, GO:0030154=IC, GO:0042803=IPI, GO:0060431=IEA, GO:0010944=TAS, GO:0006406=IDA, GO:0032993=IDA, GO:0061009=IEA, GO:0042127=IEA, GO:0022027=IEA, GO:0016055=IEA, GO:0071103=IDA, GO:0008301=IDA, GO:0000122=IDA, GO:0001701=IEA, GO:0002573=IEA, GO:0007049=IDA, GO:0061017=IEA, GO:0016973=IMP, GO:0061010=IEA, GO:0017025=TAS, GO:0061011=IEA, GO:0071837=IEA, GO:0045892=IDA, GO:0008134=IPI, GO:0030948=ISS, GO:0008283=IDA, GO:0043434=IEA, GO:0030177=ISS, GO:0005634=IDA, GO:0009952=ISS, GO:0005737=IDA, GO:0035264=IEA, GO:0048568=IEA, GO:0045944=IDA, GO:0030183=ISS, GO:0070491=IDA, GO:0035050=IEA, GO:0090009=IEA, GO:0009611=IEA, GO:0048853=IEA, GO:0006351=IEA, GO:0043565=IDA, GO:0007165=IEA, GO:0007492=IEA, GO:0031016=IEA, GO:0003682=IEA, GO:0016525=ISS, GO:0008190=IDA, GO:0001570=IEA, GO:0010621=IC, GO:0070365=IEA} B cell differentiation, DNA conformation change, Wnt receptor signaling pathway, anterior/posterior pattern specification, cell cycle, cell differentiation, cell proliferation, common bile duct development, embryonic heart tube development, embryonic organ development, endoderm development, forebrain morphogenesis, gall bladder development, hepatic duct development, hepatoblast differentiation, hepatocyte differentiation, in utero embryonic development, interkinetic nuclear migration, mRNA export from nucleus, multicellular organism growth, myeloid leukocyte differentiation, negative regulation of angiogenesis, negative regulation of transcription by competitive promoter binding, negative regulation of transcription by transcription factor localization, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, negative regulation of vascular endothelial growth factor receptor signaling pathway, pancreas development, poly(A)+ mRNA export from nucleus, positive regulation of Wnt receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, primary lung bud formation, primitive streak formation, protein localization to nucleus, regulation of cell proliferation, response to peptide hormone stimulus, response to wounding, signal transduction, thyroid gland development, transcription, DNA-dependent, vasculogenesis cytoplasm, nucleus, protein-DNA complex DNA binding, bending, HMG box domain binding, TBP-class protein binding, chromatin binding, eukaryotic initiation factor 4E binding, protein binding, protein homodimerization activity, repressing transcription factor binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding Human HHIP BHF-UCL UniProtKB {GO:0005515=PMID:19561609, GO:0048038=GO_REF:0000002, GO:0016901=GO_REF:0000002, GO:0009986=GO_REF:0000019, GO:0005975=GO_REF:0000002, GO:0048705=PMID:11435703, GO:0045879=PMID:11435703, GO:0005576=GO_REF:0000039, GO:0009953=GO_REF:0000019, GO:0007224=GO_REF:0000019, GO:0007405=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0060441=GO_REF:0000019, GO:0040036=GO_REF:0000019, GO:0005887=PMID:11435703, GO:0008270=PMID:19561609, GO:0009968=PMID:19561609, GO:0097108=PMID:19561611} Q96QV1 Hedgehog-interacting protein protein 20110804 {GO:0005515=IPI, GO:0048038=IEA, GO:0016901=IEA, GO:0009986=IEA, GO:0005975=IEA, GO:0048705=ISS, GO:0045879=ISS, GO:0005576=IEA, GO:0009953=IEA, GO:0007224=IEA, GO:0007405=IEA, GO:0005737=IEA, GO:0060441=IEA, GO:0040036=IEA, GO:0005887=ISS, GO:0008270=IDA, GO:0009968=IDA, GO:0097108=IPI} carbohydrate metabolic process, dorsal/ventral pattern formation, epithelial tube branching involved in lung morphogenesis, negative regulation of signal transduction, negative regulation of smoothened signaling pathway, neuroblast proliferation, regulation of fibroblast growth factor receptor signaling pathway, skeletal system morphogenesis, smoothened signaling pathway cell surface, cytoplasm, extracellular region, integral to plasma membrane hedgehog family protein binding, oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor, protein binding, quinone binding, zinc ion binding Human UniProtKB:O43323 HHLA3 IntAct UniProtKB {GO:0005515=PMID:16189514} Q9XRX5 HERV-H LTR-associating protein 3 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:Q13287 HIAT1 UniProtKB UniProtKB {GO:0005215=GO_REF:0000002, GO:0005886=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0055085=GO_REF:0000002} Q96MC6 Hippocampus abundant transcript 1 protein protein 20130413 {GO:0005215=IEA, GO:0005886=IEA, GO:0016021=IEA, GO:0055085=IEA} transmembrane transport integral to membrane, plasma membrane transporter activity Human UniProtKB-KW:KW-0812 HIATL1 UniProtKB UniProtKB {GO:0005215=GO_REF:0000002, GO:0005886=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0055085=GO_REF:0000002} Q5SR56 Hippocampus abundant transcript-like protein 1 protein 20130413 {GO:0005215=IEA, GO:0005886=IEA, GO:0016021=IEA, GO:0055085=IEA} transmembrane transport integral to membrane, plasma membrane transporter activity Human UniProtKB-KW:KW-0812 HIATL2 UniProtKB UniProtKB {GO:0005215=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0055085=GO_REF:0000002} Q5VZR4 Hippocampus abundant transcript-like protein 2 protein 20130413 {GO:0005215=IEA, GO:0016021=IEA, GO:0055085=IEA} transmembrane transport integral to membrane transporter activity Human UniProtKB-KW:KW-0812 HIBADH Reactome UniProtKB {GO:0005739=GO_REF:0000029, GO:0034641=Reactome:REACT_13, GO:0004616=GO_REF:0000002, GO:0051287=GO_REF:0000002, GO:0005759=Reactome:REACT_21400, GO:0006574=PMID:16466957, GO:0009083=Reactome:REACT_197, GO:0044281=Reactome:REACT_111217, GO:0008442=Reactome:REACT_21400, GO:0006098=GO_REF:0000002} P31937 3-hydroxyisobutyrate dehydrogenase, mitochondrial protein 20130213 {GO:0005739=NAS, GO:0034641=TAS, GO:0004616=IEA, GO:0051287=IEA, GO:0005759=TAS, GO:0006574=IDA, GO:0009083=TAS, GO:0044281=TAS, GO:0008442=TAS, GO:0006098=IEA} branched-chain amino acid catabolic process, cellular nitrogen compound metabolic process, pentose-phosphate shunt, small molecule metabolic process, valine catabolic process mitochondrial matrix, mitochondrion 3-hydroxyisobutyrate dehydrogenase activity, NAD binding, phosphogluconate dehydrogenase (decarboxylating) activity Human HIBCH Reactome UniProtKB {GO:0005739=GO_REF:0000019, GO:0034641=Reactome:REACT_13, GO:0005759=Reactome:REACT_919, GO:0006574=GO_REF:0000041, GO:0009083=Reactome:REACT_197, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002} Q6NVY1 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial protein 20130301 {GO:0005739=IEA, GO:0034641=TAS, GO:0005759=TAS, GO:0006574=IEA, GO:0009083=TAS, GO:0044281=TAS, GO:0003824=IEA} branched-chain amino acid catabolic process, cellular nitrogen compound metabolic process, small molecule metabolic process, valine catabolic process mitochondrial matrix, mitochondrion catalytic activity Human HIC1 HPA UniProtKB {GO:0005515=PMID:19486893, GO:0006355=PMID:7585125, GO:0003700=PMID:15231840, GO:0008630=PMID:16269335, GO:0042826=PMID:12052894, GO:0005730=GO_REF:0000052, GO:0030178=PMID:16724116, GO:0005634=GO_REF:0000052, GO:0007275=GO_REF:0000029, GO:0000122=PMID:15231840, GO:0003677=GO_REF:0000029, GO:0006351=GO_REF:0000037, GO:0043565=PMID:15231840, GO:0005737=GO_REF:0000052, GO:0043517=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0016055=GO_REF:0000037, GO:0000785=GO_REF:0000024} Q14526 Hypermethylated in cancer 1 protein protein 20110516 {GO:0005515=IPI, GO:0006355=TAS, GO:0003700=IDA, GO:0008630=IDA, GO:0042826=IDA, GO:0005730=IDA, GO:0030178=IDA, GO:0005634=IDA, GO:0007275=NAS, GO:0000122=IDA, GO:0003677=NAS, GO:0006351=IEA, GO:0043565=IDA, GO:0005737=IDA, GO:0043517=ISS, GO:0008270=IEA, GO:0016055=IEA, GO:0000785=ISS} Wnt receptor signaling pathway, intrinsic apoptotic signaling pathway in response to DNA damage, multicellular organismal development, negative regulation of Wnt receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, positive regulation of DNA damage response, signal transduction by p53 class mediator, regulation of transcription, DNA-dependent, transcription, DNA-dependent chromatin, cytoplasm, nucleolus, nucleus DNA binding, histone deacetylase binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human HIC2 HPA UniProtKB {GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0008022=PMID:12052894, GO:0005925=GO_REF:0000052, GO:0003677=PMID:11554746, GO:0045892=PMID:11554746, GO:0006351=GO_REF:0000037} Q96JB3 Hypermethylated in cancer 2 protein protein 20101115 {GO:0005886=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0008022=IPI, GO:0005925=IDA, GO:0003677=NAS, GO:0045892=NAS, GO:0006351=IEA} negative regulation of transcription, DNA-dependent, transcription, DNA-dependent focal adhesion, nucleolus, nucleus, plasma membrane DNA binding, protein C-terminus binding, zinc ion binding Human HIF1A BHF-UCL UniProtKB {GO:0010468=PMID:18419598, GO:0005515=PMID:18775313, GO:0042541=GO_REF:0000019, GO:0000988=PMID:22735262, GO:0003700=PMID:11782478, GO:0044212=PMID:99104162, GO:0051216=GO_REF:0000019, GO:0003705=PMID:7539918, GO:0001755=GO_REF:0000019, GO:0051879=PMID:9079689, GO:0051541=PMID:18037992, GO:0060574=GO_REF:0000019, GO:0006879=GO_REF:0000019, GO:0001947=GO_REF:0000019, GO:0043524=GO_REF:0000019, GO:0070101=PMID:17178876, GO:0007219=Reactome:REACT_118859, GO:0046886=PMID:1448077, GO:0046983=GO_REF:0000002, GO:0042789=PMID:7539918, GO:0045821=PMID:8089148, GO:0031625=PMID:11641274, GO:0045926=GO_REF:0000019, GO:0035035=PMID:15261140, GO:0006089=GO_REF:0000019, GO:0019901=PMID:20889502, GO:0046982=PMID:9079689, GO:0014850=GO_REF:0000019, GO:0001892=GO_REF:0000019, GO:0033554=Reactome:REACT_120956, GO:0032722=PMID:18370914, GO:0030502=GO_REF:0000019, GO:0048546=GO_REF:0000019, GO:0051000=PMID:18254728, GO:0045648=PMID:1448077, GO:0008542=GO_REF:0000019, GO:0071347=PMID:12958148, GO:0032963=PMID:18037992, GO:0019896=PMID:19528298, GO:0005654=Reactome:REACT_121374, GO:0019899=PMID:11641274, GO:0045893=PMID:8089148, GO:0032364=PMID:16956324, GO:0008134=PMID:7539918, GO:2001054=GO_REF:0000019, GO:0030949=PMID:12958148, GO:0032007=GO_REF:0000019, GO:0021987=GO_REF:0000019, GO:0042826=GO_REF:0000019, GO:0061419=PMID:22735262, GO:0061298=GO_REF:0000019, GO:0061418=Reactome:REACT_120815, GO:0005634=GO_REF:0000052, GO:0010870=PMID:17178876, GO:0001837=PMID:18037992, GO:0046716=GO_REF:0000019, GO:0005829=Reactome:REACT_121198, GO:0005737=GO_REF:0000052, GO:0045944=PMID:17981124, GO:0001922=GO_REF:0000019, GO:0004871=GO_REF:0000002, GO:0035162=GO_REF:0000019, GO:0005667=PMID:9576906, GO:0001666=PMID:8756616, GO:0006355=PMID:11782478, GO:0021502=GO_REF:0000019, GO:0035774=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0071456=Reactome:REACT_121311, GO:0002052=GO_REF:0000019, GO:0002248=PMID:18037992, GO:0043619=PMID:8387214, GO:0001525=GO_REF:0000019, GO:0042593=GO_REF:0000019, GO:0003208=GO_REF:0000019, GO:0010575=PMID:8756616, GO:0003677=GO_REF:0000038, GO:0045766=PMID:8756616, GO:0003151=GO_REF:0000019, GO:0006351=GO_REF:0000038, GO:0010573=PMID:12958148, GO:0043565=PMID:7539918, GO:0007165=PMID:12411310, GO:0006110=GO_REF:0000019, GO:0032909=PMID:12411310, GO:0001077=GO_REF:0000019, GO:0050790=GO_REF:0000019, GO:0001938=PMID:8756616, GO:0007595=GO_REF:0000019, GO:0071542=GO_REF:0000019, GO:0010634=PMID:18037992, GO:0061030=GO_REF:0000019} Q16665 Hypoxia-inducible factor 1-alpha protein 20121129 {GO:0010468=IDA, GO:0005515=IPI, GO:0042541=IEA, GO:0000988=IDA, GO:0003700=IDA, GO:0044212=IDA, GO:0051216=IEA, GO:0003705=IDA, GO:0001755=IEA, GO:0051879=IDA, GO:0051541=ISS, GO:0060574=IEA, GO:0006879=IEA, GO:0001947=IEA, GO:0043524=IEA, GO:0070101=IC, GO:0007219=TAS, GO:0046886=IDA, GO:0046983=IEA, GO:0042789=IC, GO:0045821=IC, GO:0031625=IPI, GO:0045926=IEA, GO:0035035=IPI, GO:0006089=IEA, GO:0019901=IPI, GO:0046982=IPI, GO:0014850=IEA, GO:0001892=IEA, GO:0033554=TAS, GO:0032722=TAS, GO:0030502=IEA, GO:0048546=IEA, GO:0051000=TAS, GO:0045648=IC, GO:0008542=IEA, GO:0071347=IEP, GO:0032963=ISS, GO:0019896=IMP, GO:0005654=TAS, GO:0019899=IPI, GO:0045893=IDA, GO:0032364=IDA, GO:0008134=IPI, GO:2001054=IEA, GO:0030949=IC, GO:0032007=IEA, GO:0021987=IEA, GO:0042826=IEA, GO:0061419=IDA, GO:0061298=IEA, GO:0061418=TAS, GO:0005634=IDA, GO:0010870=IMP, GO:0001837=ISS, GO:0046716=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0045944=IGI, GO:0001922=IEA, GO:0004871=IEA, GO:0035162=IEA, GO:0005667=IPI, GO:0001666=IDA, GO:0006355=IDA, GO:0021502=IEA, GO:0035774=IEA, GO:0005730=IDA, GO:0071456=TAS, GO:0002052=IEA, GO:0002248=ISS, GO:0043619=IDA, GO:0001525=IEA, GO:0042593=IEA, GO:0003208=IEA, GO:0010575=IDA, GO:0003677=IEA, GO:0045766=IC, GO:0003151=IEA, GO:0006351=IEA, GO:0010573=IDA, GO:0043565=IDA, GO:0007165=IMP, GO:0006110=IEA, GO:0032909=IMP, GO:0001077=IEA, GO:0050790=IEA, GO:0001938=IC, GO:0007595=IEA, GO:0071542=IEA, GO:0010634=ISS, GO:0061030=IEA} B-1 B cell homeostasis, Notch signaling pathway, angiogenesis, axon transport of mitochondrion, cardiac ventricle morphogenesis, cartilage development, cellular iron ion homeostasis, cellular response to hypoxia, cellular response to interleukin-1, cellular response to stress, cerebral cortex development, collagen metabolic process, connective tissue replacement involved in inflammatory response wound healing, digestive tract morphogenesis, dopaminergic neuron differentiation, elastin metabolic process, embryonic hemopoiesis, embryonic placenta development, epithelial cell differentiation involved in mammary gland alveolus development, epithelial to mesenchymal transition, glucose homeostasis, heart looping, hemoglobin biosynthetic process, intestinal epithelial cell maturation, lactate metabolic process, lactation, mRNA transcription from RNA polymerase II promoter, muscle cell homeostasis, negative regulation of TOR signaling cascade, negative regulation of bone mineralization, negative regulation of growth, negative regulation of mesenchymal cell apoptotic process, negative regulation of neuron apoptotic process, neural crest cell migration, neural fold elevation formation, outflow tract morphogenesis, oxygen homeostasis, positive regulation of angiogenesis, positive regulation of chemokine production, positive regulation of chemokine-mediated signaling pathway, positive regulation of endothelial cell proliferation, positive regulation of epithelial cell migration, positive regulation of erythrocyte differentiation, positive regulation of glycolysis, positive regulation of hormone biosynthetic process, positive regulation of insulin secretion involved in cellular response to glucose stimulus, positive regulation of neuroblast proliferation, positive regulation of nitric-oxide synthase activity, positive regulation of receptor biosynthetic process, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter in response to hypoxia, positive regulation of transcription, DNA-dependent, positive regulation of vascular endothelial growth factor receptor signaling pathway, positive regulation vascular endothelial growth factor production, regulation of catalytic activity, regulation of gene expression, regulation of glycolysis, regulation of transcription from RNA polymerase II promoter in response to hypoxia, regulation of transcription from RNA polymerase II promoter in response to oxidative stress, regulation of transcription, DNA-dependent, regulation of transforming growth factor beta2 production, response to hypoxia, response to muscle activity, retina vasculature development in camera-type eye, signal transduction, transcription, DNA-dependent, vascular endothelial growth factor production, visual learning cytoplasm, cytosol, nucleolus, nucleoplasm, nucleus, transcription factor complex DNA binding, Hsp90 protein binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, enzyme binding, histone acetyltransferase binding, histone deacetylase binding, protein binding, protein binding transcription factor activity, protein dimerization activity, protein heterodimerization activity, protein kinase binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, signal transducer activity, transcription factor binding, transcription regulatory region DNA binding, ubiquitin protein ligase binding Human HIF1AN IntAct UniProtKB {GO:0031406=PMID:17135241, GO:0005515=PMID:19060904, GO:0048471=PMID:19726677, GO:0042265=PMID:21177872, GO:2001214=PMID:17636018, GO:0036138=PMID:21251231, GO:0042264=PMID:21177872, GO:0036139=PMID:21251231, GO:0061418=Reactome:REACT_120815, GO:0005112=PMID:18299578, GO:0005634=PMID:18299578, GO:0042803=PMID:12446723, GO:0005829=Reactome:REACT_121198, GO:0005737=PMID:14734545, GO:0036140=PMID:12215170, GO:0071532=PMID:21251231, GO:0045746=PMID:18299578, GO:0048037=PMID:12446723, GO:0051059=PMID:17003112, GO:0005506=PMID:12446723, GO:0071456=Reactome:REACT_121311, GO:0033554=Reactome:REACT_120956, GO:0061428=PMID:11641274, GO:0006351=GO_REF:0000037, GO:0045663=PMID:18299578, GO:0019826=PMID:12080085, GO:0016706=Reactome:REACT_121198, GO:0008270=PMID:12446723, GO:0016702=GO_REF:0000037, GO:0055114=PMID:12215170} Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor protein 20130415 {GO:0031406=IDA, GO:0005515=IPI, GO:0048471=IDA, GO:0042265=IDA, GO:2001214=NAS, GO:0036138=IDA, GO:0042264=IDA, GO:0036139=IDA, GO:0061418=TAS, GO:0005112=IPI, GO:0005634=IDA, GO:0042803=IDA, GO:0005829=TAS, GO:0005737=IDA, GO:0036140=IDA, GO:0071532=IPI, GO:0045746=IDA, GO:0048037=IDA, GO:0051059=IPI, GO:0005506=IDA, GO:0071456=TAS, GO:0033554=TAS, GO:0061428=IDA, GO:0006351=IEA, GO:0045663=IDA, GO:0019826=NAS, GO:0016706=EXP, GO:0008270=IDA, GO:0016702=IEA, GO:0055114=IDA} cellular response to hypoxia, cellular response to stress, negative regulation of Notch signaling pathway, negative regulation of transcription from RNA polymerase II promoter in response to hypoxia, oxidation-reduction process, peptidyl-asparagine hydroxylation, peptidyl-aspartic acid hydroxylation, peptidyl-histidine hydroxylation, positive regulation of myoblast differentiation, positive regulation of vasculogenesis, regulation of transcription from RNA polymerase II promoter in response to hypoxia, transcription, DNA-dependent cytoplasm, cytosol, nucleus, perinuclear region of cytoplasm NF-kappaB binding, Notch binding, ankyrin repeat binding, carboxylic acid binding, cofactor binding, iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, oxygen sensor activity, peptidyl-asparagine 3-dioxygenase activity, peptidyl-histidine dioxygenase activity, protein binding, protein homodimerization activity, zinc ion binding Human UniProtKB:Q96DX5 HIF3A HPA UniProtKB {GO:0001666=GO_REF:0000019, GO:0006355=GO_REF:0000002, GO:0003700=GO_REF:0000019, GO:0006366=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0071456=Reactome:REACT_121311, GO:0061418=Reactome:REACT_120815, GO:0005634=GO_REF:0000052, GO:0033554=Reactome:REACT_120956, GO:0003677=GO_REF:0000019, GO:0005829=Reactome:REACT_121242, GO:0005737=GO_REF:0000052, GO:0046983=GO_REF:0000002, GO:0005654=Reactome:REACT_121374, GO:0004871=GO_REF:0000002} Q9Y2N7 Hypoxia-inducible factor 3-alpha protein 20110516 {GO:0001666=IEA, GO:0006355=IEA, GO:0003700=IEA, GO:0006366=IEA, GO:0005886=IDA, GO:0071456=TAS, GO:0061418=TAS, GO:0005634=IDA, GO:0033554=TAS, GO:0003677=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0046983=IEA, GO:0005654=TAS, GO:0004871=IEA} cellular response to hypoxia, cellular response to stress, regulation of transcription from RNA polymerase II promoter in response to hypoxia, regulation of transcription, DNA-dependent, response to hypoxia, transcription from RNA polymerase II promoter cytoplasm, cytosol, nucleoplasm, nucleus, plasma membrane DNA binding, protein dimerization activity, sequence-specific DNA binding transcription factor activity, signal transducer activity Human HIGD1A LIFEdb UniProtKB {GO:0043234=GO_REF:0000054, GO:0043066=PMID:21856340, GO:0070469=GO_REF:0000037, GO:0005743=GO_REF:0000039, GO:0006950=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0022900=GO_REF:0000037} Q9Y241 HIG1 domain family member 1A, mitochondrial protein 20100607 {GO:0043234=IDA, GO:0043066=IDA, GO:0070469=IEA, GO:0005743=IEA, GO:0006950=IEA, GO:0016021=IEA, GO:0022900=IEA} electron transport chain, negative regulation of apoptotic process, response to stress integral to membrane, mitochondrial inner membrane, protein complex, respiratory chain Human HIGD1B UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9P298 HIG1 domain family member 1B protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 HIGD2A MGI UniProtKB {GO:0043066=PMID:21856340, GO:0070469=GO_REF:0000037, GO:0005743=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0022900=GO_REF:0000037} Q9BW72 HIG1 domain family member 2A, mitochondrial protein 20120315 {GO:0043066=IDA, GO:0070469=IEA, GO:0005743=IEA, GO:0016021=IEA, GO:0022900=IEA} electron transport chain, negative regulation of apoptotic process integral to membrane, mitochondrial inner membrane, respiratory chain Human HILPDA BHF-UCL UniProtKB {GO:0005811=PMID:20624928, GO:0008284=PMID:15930302, GO:0009986=PMID:15930302, GO:0005102=PMID:15930302, GO:0006950=PMID:10690527, GO:0010884=PMID:20624928, GO:0035425=PMID:15930302, GO:0001819=PMID:20624928, GO:0016021=GO_REF:0000037, GO:0030141=PMID:15930302, GO:0005615=PMID:15930302} Q9Y5L2 Hypoxia-inducible lipid droplet-associated protein protein 20100806 {GO:0005811=IDA, GO:0008284=IDA, GO:0009986=IDA, GO:0005102=IPI, GO:0006950=NAS, GO:0010884=IDA, GO:0035425=IDA, GO:0001819=IDA, GO:0016021=IEA, GO:0030141=IDA, GO:0005615=IDA} autocrine signaling, positive regulation of cell proliferation, positive regulation of cytokine production, positive regulation of lipid storage, response to stress cell surface, extracellular space, integral to membrane, lipid particle, secretory granule receptor binding Human HINFP UniProtKB UniProtKB {GO:0005515=PMID:18850719, GO:0010468=PMID:15988025, GO:0015030=PMID:15988025, GO:0003700=PMID:9540062, GO:0044212=PMID:14752047, GO:0005634=PMID:18850719, GO:0045184=PMID:15988025, GO:0042393=PMID:14585971, GO:0000082=PMID:14585971, GO:0000083=PMID:15988025, GO:0045445=PMID:15541338, GO:0006355=PMID:9540062, GO:0003713=PMID:19170105, GO:0005730=PMID:11553631, GO:0001701=GO_REF:0000024, GO:0003677=PMID:18850719, GO:0006351=GO_REF:0000019, GO:0010628=PMID:14585971, GO:0006281=PMID:17974976, GO:0003682=GO_REF:0000019, GO:0010629=PMID:15541338, GO:0008270=GO_REF:0000002, GO:0005654=PMID:11553631, GO:0000077=PMID:17974976, GO:0045893=PMID:17163457, GO:0019899=PMID:11553631, GO:0045892=PMID:17163457} Q9BQA5 Histone H4 transcription factor protein 20090717 {GO:0005515=IPI, GO:0010468=IMP, GO:0015030=IDA, GO:0003700=IMP, GO:0044212=IDA, GO:0005634=IDA, GO:0045184=IMP, GO:0042393=IPI, GO:0000082=IMP, GO:0000083=IMP, GO:0045445=IMP, GO:0006355=IMP, GO:0003713=IDA, GO:0005730=IDA, GO:0001701=ISS, GO:0003677=IDA, GO:0006351=IEA, GO:0010628=IMP, GO:0006281=IMP, GO:0003682=IEA, GO:0010629=IMP, GO:0008270=IEA, GO:0005654=IDA, GO:0000077=IMP, GO:0045893=IDA, GO:0019899=IPI, GO:0045892=IDA} DNA damage checkpoint, DNA repair, G1/S transition of mitotic cell cycle, establishment of protein localization, in utero embryonic development, myoblast differentiation, negative regulation of gene expression, negative regulation of transcription, DNA-dependent, positive regulation of gene expression, positive regulation of transcription, DNA-dependent, regulation of gene expression, regulation of transcription involved in G1/S phase of mitotic cell cycle, regulation of transcription, DNA-dependent, transcription, DNA-dependent Cajal body, nucleolus, nucleoplasm, nucleus DNA binding, chromatin binding, enzyme binding, histone binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, transcription regulatory region DNA binding, zinc ion binding Human UniProtKB:Q14207 HINT1 HPA UniProtKB {GO:0006355=PMID:16835243, GO:0005886=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003824=GO_REF:0000002, GO:0009154=PMID:16835243, GO:0006351=GO_REF:0000037, GO:0007165=PMID:8812426, GO:0005737=GO_REF:0000052, GO:0000118=PMID:16835243, GO:0000166=GO_REF:0000037, GO:0016787=PMID:16835243, GO:0072332=PMID:16835243, GO:0005080=PMID:9770345, GO:0005856=PMID:8812426} P49773 Histidine triad nucleotide-binding protein 1 protein 20111111 {GO:0006355=IMP, GO:0005886=IDA, GO:0005634=IDA, GO:0003824=IEA, GO:0009154=IDA, GO:0006351=IEA, GO:0007165=TAS, GO:0005737=IDA, GO:0000118=IDA, GO:0000166=IEA, GO:0016787=IDA, GO:0072332=IMP, GO:0005080=TAS, GO:0005856=TAS} intrinsic apoptotic signaling pathway by p53 class mediator, purine ribonucleotide catabolic process, regulation of transcription, DNA-dependent, signal transduction, transcription, DNA-dependent cytoplasm, cytoskeleton, histone deacetylase complex, nucleus, plasma membrane catalytic activity, hydrolase activity, nucleotide binding, protein kinase C binding Human HINT2 UniProtKB UniProtKB {GO:0005739=GO_REF:0000024, GO:0006694=GO_REF:0000037, GO:0016787=GO_REF:0000037, GO:0000166=GO_REF:0000037, GO:0006915=GO_REF:0000037} Q9BX68 Histidine triad nucleotide-binding protein 2, mitochondrial protein 20041006 {GO:0005739=ISS, GO:0006694=IEA, GO:0016787=IEA, GO:0000166=IEA, GO:0006915=IEA} apoptotic process, steroid biosynthetic process mitochondrion hydrolase activity, nucleotide binding Human UniProtKB:Q9D0S9 HINT3 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0016787=GO_REF:0000037, GO:0000166=GO_REF:0000037, GO:0005730=GO_REF:0000052} Q9NQE9 Histidine triad nucleotide-binding protein 3 protein 20101115 {GO:0005739=IDA, GO:0005737=IDA, GO:0016787=IEA, GO:0000166=IEA, GO:0005730=IDA} cytoplasm, mitochondrion, nucleolus hydrolase activity, nucleotide binding Human HIP1 HPA UniProtKB {GO:0005515=PMID:11788820, GO:0006355=GO_REF:0000037, GO:0005794=PMID:11788820, GO:0006919=PMID:11788820, GO:0030136=PMID:11517213, GO:0006915=PMID:11788820, GO:0042981=PMID:11788820, GO:0003779=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006917=PMID:11007801, GO:0006351=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0006897=GO_REF:0000019, GO:0030665=GO_REF:0000039, GO:0005737=PMID:11604514, GO:0005543=GO_REF:0000002, GO:0016020=PMID:9147654, GO:0030276=PMID:11577110, GO:0048260=PMID:11577110, GO:0005200=PMID:9140394, GO:0005856=PMID:9147654, GO:0035091=PMID:14732715, GO:0048268=PMID:11577110} O00291 Huntingtin-interacting protein 1 protein 20101115 {GO:0005515=IPI, GO:0006355=IEA, GO:0005794=IDA, GO:0006919=IDA, GO:0030136=IDA, GO:0006915=IDA, GO:0042981=IDA, GO:0003779=IEA, GO:0005634=IEA, GO:0006917=IDA, GO:0006351=IEA, GO:0030154=IEA, GO:0043231=IDA, GO:0006897=IEA, GO:0030665=IEA, GO:0005737=IDA, GO:0005543=IEA, GO:0016020=TAS, GO:0030276=IDA, GO:0048260=IMP, GO:0005200=TAS, GO:0005856=TAS, GO:0035091=IDA, GO:0048268=IDA} activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, cell differentiation, clathrin coat assembly, endocytosis, induction of apoptosis, positive regulation of receptor-mediated endocytosis, regulation of apoptotic process, regulation of transcription, DNA-dependent, transcription, DNA-dependent Golgi apparatus, clathrin-coated vesicle, clathrin-coated vesicle membrane, cytoplasm, cytoskeleton, intracellular membrane-bounded organelle, membrane, nucleus actin binding, clathrin binding, phosphatidylinositol binding, phospholipid binding, protein binding, structural constituent of cytoskeleton Human HIP1R UniProtKB UniProtKB {GO:0005515=PMID:15533940, GO:0030665=GO_REF:0000039, GO:0005905=GO_REF:0000029, GO:0048471=GO_REF:0000039, GO:0030136=PMID:14732715, GO:0003779=GO_REF:0000029, GO:0035091=PMID:14732715, GO:0005856=GO_REF:0000019, GO:0006898=PMID:11889126} O75146 Huntingtin-interacting protein 1-related protein protein 20100507 {GO:0005515=IPI, GO:0030665=IEA, GO:0005905=NAS, GO:0048471=IEA, GO:0030136=IDA, GO:0003779=NAS, GO:0035091=IDA, GO:0005856=IEA, GO:0006898=IMP} receptor-mediated endocytosis clathrin-coated vesicle, clathrin-coated vesicle membrane, coated pit, cytoskeleton, perinuclear region of cytoplasm actin binding, phosphatidylinositol binding, protein binding Human HIPK1 IntAct UniProtKB {GO:0005515=PMID:12702766, GO:0006355=GO_REF:0000037, GO:0008284=GO_REF:0000019, GO:0060235=GO_REF:0000019, GO:0001654=PMID:20579985, GO:0006915=PMID:15701637, GO:0060216=PMID:20231426, GO:0010842=GO_REF:0000019, GO:0061072=GO_REF:0000019, GO:0060059=GO_REF:0000019, GO:0010803=PMID:15701637, GO:0009952=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0045766=PMID:16917507, GO:0006351=GO_REF:0000037, GO:0048596=GO_REF:0000019, GO:0007224=GO_REF:0000019, GO:0042771=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0016607=GO_REF:0000019, GO:0004674=GO_REF:0000037, GO:0016605=GO_REF:0000019, GO:0030182=GO_REF:0000019} Q86Z02 Homeodomain-interacting protein kinase 1 protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0008284=IEA, GO:0060235=IEA, GO:0001654=ISS, GO:0006915=IDA, GO:0060216=ISS, GO:0010842=IEA, GO:0061072=IEA, GO:0060059=IEA, GO:0010803=IDA, GO:0009952=IEA, GO:0005524=IEA, GO:0045766=ISS, GO:0006351=IEA, GO:0048596=IEA, GO:0007224=IEA, GO:0042771=IEA, GO:0005737=IEA, GO:0016607=IEA, GO:0004674=IEA, GO:0016605=IEA, GO:0030182=IEA} anterior/posterior pattern specification, apoptotic process, definitive hemopoiesis, embryonic camera-type eye morphogenesis, embryonic retina morphogenesis in camera-type eye, eye development, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, iris morphogenesis, lens induction in camera-type eye, neuron differentiation, positive regulation of angiogenesis, positive regulation of cell proliferation, regulation of transcription, DNA-dependent, regulation of tumor necrosis factor-mediated signaling pathway, retina layer formation, smoothened signaling pathway, transcription, DNA-dependent PML body, cytoplasm, nuclear speck ATP binding, protein binding, protein serine/threonine kinase activity Human UniProtKB:P04637 HIPK2 HPA UniProtKB {GO:0005515=PMID:14647468, GO:0001654=PMID:20579985, GO:0046330=PMID:14678985, GO:0046332=PMID:12874272, GO:0048596=GO_REF:0000019, GO:0007224=GO_REF:0000019, GO:0043524=GO_REF:0000019, GO:0030578=PMID:18974774, GO:0018105=GO_REF:0000024, GO:0050882=GO_REF:0000019, GO:0018107=GO_REF:0000024, GO:0007179=GO_REF:0000019, GO:0006978=PMID:14647468, GO:0001102=GO_REF:0000024, GO:0031965=GO_REF:0000052, GO:0001105=GO_REF:0000024, GO:0005813=GO_REF:0000052, GO:0060235=GO_REF:0000019, GO:0003714=PMID:12874272, GO:0046790=PMID:14990717, GO:0010842=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0042771=PMID:18974774, GO:0043388=GO_REF:0000019, GO:0045893=PMID:14647468, GO:0008284=GO_REF:0000019, GO:0061072=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0009952=GO_REF:0000019, GO:0060395=PMID:12874272, GO:0032092=GO_REF:0000024, GO:0030514=PMID:12874272, GO:0005737=GO_REF:0000024, GO:0051091=GO_REF:0000024, GO:0030182=GO_REF:0000019, GO:0045944=GO_REF:0000024, GO:0007628=GO_REF:0000019, GO:0051726=PMID:18974774, GO:0030511=PMID:14678985, GO:0071456=PMID:18974774, GO:0060059=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0097193=PMID:15122315, GO:0045766=PMID:19046997, GO:0016604=PMID:14626429, GO:0004672=PMID:9748262, GO:0004674=GO_REF:0000024, GO:0019048=PMID:14990717, GO:0016605=PMID:14647468, GO:0030218=PMID:20231426} Q9H2X6 Homeodomain-interacting protein kinase 2 protein 20101115 {GO:0005515=IPI, GO:0001654=ISS, GO:0046330=IMP, GO:0046332=IPI, GO:0048596=IEA, GO:0007224=IEA, GO:0043524=IEA, GO:0030578=TAS, GO:0018105=ISS, GO:0050882=IEA, GO:0018107=ISS, GO:0007179=IEA, GO:0006978=IDA, GO:0001102=ISS, GO:0031965=IDA, GO:0001105=ISS, GO:0005813=IDA, GO:0060235=IEA, GO:0003714=IDA, GO:0046790=IPI, GO:0010842=IEA, GO:0000122=IEA, GO:0042771=TAS, GO:0043388=IEA, GO:0045893=IMP, GO:0008284=IEA, GO:0061072=IEA, GO:0005634=IDA, GO:0009952=IEA, GO:0060395=IDA, GO:0032092=ISS, GO:0030514=IMP, GO:0005737=ISS, GO:0051091=ISS, GO:0030182=IEA, GO:0045944=ISS, GO:0007628=IEA, GO:0051726=TAS, GO:0030511=IMP, GO:0071456=TAS, GO:0060059=IEA, GO:0005524=IEA, GO:0097193=NAS, GO:0045766=IDA, GO:0016604=TAS, GO:0004672=TAS, GO:0004674=ISS, GO:0019048=NAS, GO:0016605=IDA, GO:0030218=ISS} DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, PML body organization, SMAD protein signal transduction, adult walking behavior, anterior/posterior pattern specification, cellular response to hypoxia, embryonic camera-type eye morphogenesis, embryonic retina morphogenesis in camera-type eye, erythrocyte differentiation, eye development, intrinsic apoptotic signaling pathway, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, iris morphogenesis, lens induction in camera-type eye, negative regulation of BMP signaling pathway, negative regulation of neuron apoptotic process, negative regulation of transcription from RNA polymerase II promoter, neuron differentiation, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, positive regulation of DNA binding, positive regulation of JNK cascade, positive regulation of angiogenesis, positive regulation of cell proliferation, positive regulation of protein binding, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of transforming growth factor beta receptor signaling pathway, regulation of cell cycle, retina layer formation, smoothened signaling pathway, transforming growth factor beta receptor signaling pathway, virus-host interaction, voluntary musculoskeletal movement PML body, centrosome, cytoplasm, nuclear body, nuclear membrane, nucleus ATP binding, RNA polymerase II activating transcription factor binding, RNA polymerase II transcription coactivator activity, SMAD binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, transcription corepressor activity, virion binding Human HIPK3 HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0043066=PMID:14766760, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000029, GO:0005737=GO_REF:0000052, GO:0004672=PMID:14766760, GO:0018105=PMID:11034606, GO:0004674=PMID:10919273, GO:0016605=GO_REF:0000019, GO:0018107=PMID:11034606, GO:0006468=PMID:14766760, GO:0009299=PMID:17210646, GO:0043508=GO_REF:0000024} Q9H422 Homeodomain-interacting protein kinase 3 protein 20101115 {GO:0006355=IEA, GO:0043066=IMP, GO:0006915=IEA, GO:0005634=IDA, GO:0005524=NAS, GO:0005737=IDA, GO:0004672=IDA, GO:0018105=ISS, GO:0004674=IDA, GO:0016605=IEA, GO:0018107=ISS, GO:0006468=IDA, GO:0009299=IDA, GO:0043508=ISS} apoptotic process, mRNA transcription, negative regulation of JUN kinase activity, negative regulation of apoptotic process, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, protein phosphorylation, regulation of transcription, DNA-dependent PML body, cytoplasm, nucleus ATP binding, protein kinase activity, protein serine/threonine kinase activity Human HIPK4 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0004674=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q8NE63 Homeodomain-interacting protein kinase 4 protein 20130413 {GO:0005737=IEA, GO:0004674=IEA, GO:0005524=IEA} cytoplasm ATP binding, protein serine/threonine kinase activity Human UniProtKB-SubCell:SL-0086 HIRA PINC UniProtKB {GO:0005515=PMID:9710638, GO:0006355=GO_REF:0000002, GO:0000790=GO_REF:0000019, GO:0007369=GO_REF:0000019, GO:0003700=PMID:9731536, GO:0006357=PMID:9731536, GO:0003714=PMID:9731536, GO:0005634=PMID:9710638, GO:0009653=PMID:7633437, GO:0001649=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0042692=GO_REF:0000019, GO:0003682=GO_REF:0000002, GO:0016605=GO_REF:0000039, GO:0016568=GO_REF:0000037} P54198 Protein HIRA protein 20031119 {GO:0005515=IPI, GO:0006355=IEA, GO:0000790=IEA, GO:0007369=IEA, GO:0003700=TAS, GO:0006357=TAS, GO:0003714=TAS, GO:0005634=TAS, GO:0009653=TAS, GO:0001649=IEA, GO:0006351=IEA, GO:0042692=IEA, GO:0003682=IEA, GO:0016605=IEA, GO:0016568=IEA} anatomical structure morphogenesis, chromatin modification, gastrulation, muscle cell differentiation, osteoblast differentiation, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription, DNA-dependent PML body, nuclear chromatin, nucleus chromatin binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human HIRIP3 PINC UniProtKB {GO:0005515=PMID:9710638, GO:0005634=PMID:17391060, GO:0006333=PMID:9710638} Q9BW71 HIRA-interacting protein 3 protein 20050308 {GO:0005515=IPI, GO:0005634=IDA, GO:0006333=TAS} chromatin assembly or disassembly nucleus protein binding Human HIST1H1A UniProtKB UniProtKB {GO:0000790=PMID:19882353, GO:0006334=GO_REF:0000002, GO:0007283=GO_REF:0000019, GO:0000786=GO_REF:0000002, GO:0003677=GO_REF:0000019} Q02539 Histone H1.1 protein 20120118 {GO:0000790=IDA, GO:0006334=IEA, GO:0007283=IEA, GO:0000786=IEA, GO:0003677=IEA} nucleosome assembly, spermatogenesis nuclear chromatin, nucleosome DNA binding Human HIST1H1B UniProtKB UniProtKB {GO:0000790=PMID:19882353, GO:0006334=GO_REF:0000029, GO:0000786=GO_REF:0000029, GO:0003677=GO_REF:0000029} P16401 Histone H1.5 protein 20120118 {GO:0000790=IDA, GO:0006334=NAS, GO:0000786=NAS, GO:0003677=NAS} nucleosome assembly nuclear chromatin, nucleosome DNA binding Human HIST1H1C UniProtKB UniProtKB {GO:0006334=GO_REF:0000029, GO:0005634=GO_REF:0000039, GO:0000786=GO_REF:0000029, GO:0003677=GO_REF:0000029} P16403 Histone H1.2 protein 20030424 {GO:0006334=NAS, GO:0005634=IEA, GO:0000786=NAS, GO:0003677=NAS} nucleosome assembly nucleosome, nucleus DNA binding Human HIST1H1D UniProtKB UniProtKB {GO:0000790=PMID:19882353, GO:0006334=GO_REF:0000029, GO:0000786=GO_REF:0000029, GO:0003677=GO_REF:0000029} P16402 Histone H1.3 protein 20120118 {GO:0000790=IDA, GO:0006334=NAS, GO:0000786=NAS, GO:0003677=NAS} nucleosome assembly nuclear chromatin, nucleosome DNA binding Human HIST1H1E BHF-UCL UniProtKB {GO:0005515=PMID:15469825, GO:0006334=GO_REF:0000029, GO:0016584=GO_REF:0000019, GO:0005634=PMID:17540172, GO:0000786=GO_REF:0000029, GO:0003677=GO_REF:0000029} P10412 Histone H1.4 protein 20080912 {GO:0005515=IPI, GO:0006334=NAS, GO:0016584=IEA, GO:0005634=IDA, GO:0000786=NAS, GO:0003677=NAS} nucleosome assembly, nucleosome positioning nucleosome, nucleus DNA binding, protein binding Human UniProtKB:Q96EB6 HIST1H1T ENSEMBL UniProtKB {GO:0000794=GO_REF:0000019, GO:0006334=GO_REF:0000002, GO:0007275=GO_REF:0000037, GO:0030317=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0007339=GO_REF:0000019, GO:0000786=GO_REF:0000002, GO:0003677=GO_REF:0000019, GO:0030154=GO_REF:0000037} P22492 Histone H1t protein 20130413 {GO:0000794=IEA, GO:0006334=IEA, GO:0007275=IEA, GO:0030317=IEA, GO:0007283=IEA, GO:0007339=IEA, GO:0000786=IEA, GO:0003677=IEA, GO:0030154=IEA} binding of sperm to zona pellucida, cell differentiation, multicellular organismal development, nucleosome assembly, sperm motility, spermatogenesis condensed nuclear chromosome, nucleosome DNA binding Human Ensembl:ENSMUSP00000037304 HIST1H2AA UniProtKB UniProtKB {GO:0046982=GO_REF:0000002, GO:0006334=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0000786=GO_REF:0000037, GO:0003677=GO_REF:0000037} Q96QV6 Histone H2A type 1-A protein 20130413 {GO:0046982=IEA, GO:0006334=IEA, GO:0005634=IEA, GO:0000786=IEA, GO:0003677=IEA} nucleosome assembly nucleosome, nucleus DNA binding, protein heterodimerization activity Human UniProtKB-SubCell:SL-0191 HIST1H2AB UniProtKB UniProtKB {GO:0046982=GO_REF:0000002, GO:0006334=GO_REF:0000029, GO:0005634=GO_REF:0000039, GO:0000786=GO_REF:0000029, GO:0003677=PMID:6647026} P04908 Histone H2A type 1-B/E protein 20030424 {GO:0046982=IEA, GO:0006334=NAS, GO:0005634=IEA, GO:0000786=NAS, GO:0003677=NAS} nucleosome assembly nucleosome, nucleus DNA binding, protein heterodimerization activity Human HIST1H2AC UniProtKB UniProtKB {GO:0046982=GO_REF:0000002, GO:0006334=GO_REF:0000029, GO:0005634=GO_REF:0000039, GO:0000786=GO_REF:0000029, GO:0003677=GO_REF:0000029} Q93077 Histone H2A type 1-C protein 20030424 {GO:0046982=IEA, GO:0006334=NAS, GO:0005634=IEA, GO:0000786=NAS, GO:0003677=NAS} nucleosome assembly nucleosome, nucleus DNA binding, protein heterodimerization activity Human HIST1H2AD UniProtKB UniProtKB {GO:0046982=GO_REF:0000002, GO:0006334=GO_REF:0000029, GO:0005634=GO_REF:0000039, GO:0000786=GO_REF:0000029, GO:0003677=GO_REF:0000029} P20671 Histone H2A type 1-D protein 20030424 {GO:0046982=IEA, GO:0006334=NAS, GO:0005634=IEA, GO:0000786=NAS, GO:0003677=NAS} nucleosome assembly nucleosome, nucleus DNA binding, protein heterodimerization activity Human HIST1H2AE null null {} null null null null {} null null null HIST1H2AG UniProtKB UniProtKB {GO:0046982=GO_REF:0000002, GO:0006334=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0019899=PMID:17980597, GO:0000786=GO_REF:0000037, GO:0003677=GO_REF:0000037} P0C0S8 Histone H2A type 1 protein 20100610 {GO:0046982=IEA, GO:0006334=IEA, GO:0005634=IEA, GO:0019899=IPI, GO:0000786=IEA, GO:0003677=IEA} nucleosome assembly nucleosome, nucleus DNA binding, enzyme binding, protein heterodimerization activity Human UniProtKB:Q9Y6I4 HIST1H2AH UniProtKB UniProtKB {GO:0046982=GO_REF:0000002, GO:0006334=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0000786=GO_REF:0000037, GO:0003677=GO_REF:0000037} Q96KK5 Histone H2A type 1-H protein 20130413 {GO:0046982=IEA, GO:0006334=IEA, GO:0005634=IEA, GO:0000786=IEA, GO:0003677=IEA} nucleosome assembly nucleosome, nucleus DNA binding, protein heterodimerization activity Human UniProtKB-SubCell:SL-0191 HIST1H2AI null null {} null null null null {} null null null HIST1H2AJ UniProtKB UniProtKB {GO:0046982=GO_REF:0000002, GO:0006334=GO_REF:0000029, GO:0005634=GO_REF:0000039, GO:0000786=GO_REF:0000029, GO:0003677=GO_REF:0000029} Q99878 Histone H2A type 1-J protein 20030424 {GO:0046982=IEA, GO:0006334=NAS, GO:0005634=IEA, GO:0000786=NAS, GO:0003677=NAS} nucleosome assembly nucleosome, nucleus DNA binding, protein heterodimerization activity Human HIST1H2AK null null {} null null null null {} null null null HIST1H2AL null null {} null null null null {} null null null HIST1H2AM null null {} null null null null {} null null null HIST1H2BA UniProtKB UniProtKB {GO:0006954=GO_REF:0000019, GO:0046982=GO_REF:0000002, GO:0071229=GO_REF:0000019, GO:0006334=GO_REF:0000002, GO:0031639=GO_REF:0000019, GO:0051099=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0071674=GO_REF:0000019, GO:0000786=GO_REF:0000037, GO:0003677=GO_REF:0000019, GO:0019897=GO_REF:0000019} Q96A08 Histone H2B type 1-A protein 20130413 {GO:0006954=IEA, GO:0046982=IEA, GO:0071229=IEA, GO:0006334=IEA, GO:0031639=IEA, GO:0051099=IEA, GO:0005634=IEA, GO:0071674=IEA, GO:0000786=IEA, GO:0003677=IEA, GO:0019897=IEA} cellular response to acid, inflammatory response, mononuclear cell migration, nucleosome assembly, plasminogen activation, positive regulation of binding extrinsic to plasma membrane, nucleosome, nucleus DNA binding, protein heterodimerization activity Human UniProtKB-SubCell:SL-0191 HIST1H2BB UniProtKB UniProtKB {GO:0046982=GO_REF:0000002, GO:0006334=PMID:9439656, GO:0005634=GO_REF:0000039, GO:0000786=PMID:9439656, GO:0003677=PMID:9439656} P33778 Histone H2B type 1-B protein 20030424 {GO:0046982=IEA, GO:0006334=NAS, GO:0005634=IEA, GO:0000786=NAS, GO:0003677=NAS} nucleosome assembly nucleosome, nucleus DNA binding, protein heterodimerization activity Human HIST1H2BC UniProtKB UniProtKB {GO:0046982=GO_REF:0000002, GO:0006334=PMID:422550, GO:0005634=GO_REF:0000039, GO:0000786=PMID:422550, GO:0003677=PMID:422550, GO:0042742=GO_REF:0000037} P62807 Histone H2B type 1-C/E/F/G/I protein 20041129 {GO:0046982=IEA, GO:0006334=NAS, GO:0005634=IEA, GO:0000786=NAS, GO:0003677=NAS, GO:0042742=IEA} defense response to bacterium, nucleosome assembly nucleosome, nucleus DNA binding, protein heterodimerization activity Human HIST1H2BD UniProtKB UniProtKB {GO:0046982=GO_REF:0000002, GO:0006334=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0000786=GO_REF:0000037, GO:0003677=GO_REF:0000037} P58876 Histone H2B type 1-D protein 20130413 {GO:0046982=IEA, GO:0006334=IEA, GO:0005634=IEA, GO:0000786=IEA, GO:0003677=IEA} nucleosome assembly nucleosome, nucleus DNA binding, protein heterodimerization activity Human UniProtKB-SubCell:SL-0191 HIST1H2BE null null {} null null null null {} null null null HIST1H2BF null null {} null null null null {} null null null HIST1H2BG null null {} null null null null {} null null null HIST1H2BH UniProtKB UniProtKB {GO:0046982=GO_REF:0000002, GO:0006334=PMID:9119399, GO:0005634=GO_REF:0000039, GO:0000786=PMID:9119399, GO:0003677=PMID:9119399} Q93079 Histone H2B type 1-H protein 20030424 {GO:0046982=IEA, GO:0006334=NAS, GO:0005634=IEA, GO:0000786=NAS, GO:0003677=NAS} nucleosome assembly nucleosome, nucleus DNA binding, protein heterodimerization activity Human HIST1H2BI null null {} null null null null {} null null null HIST1H2BJ UniProtKB UniProtKB {GO:0046982=GO_REF:0000002, GO:0006334=PMID:6647026, GO:0005634=GO_REF:0000039, GO:0000786=PMID:6647026, GO:0003677=PMID:6647026, GO:0042742=GO_REF:0000037} P06899 Histone H2B type 1-J protein 20030424 {GO:0046982=IEA, GO:0006334=NAS, GO:0005634=IEA, GO:0000786=NAS, GO:0003677=NAS, GO:0042742=IEA} defense response to bacterium, nucleosome assembly nucleosome, nucleus DNA binding, protein heterodimerization activity Human HIST1H2BK UniProtKB UniProtKB {GO:0046982=GO_REF:0000002, GO:0006334=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0000786=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0042742=GO_REF:0000037} O60814 Histone H2B type 1-K protein 20130413 {GO:0046982=IEA, GO:0006334=IEA, GO:0005634=IEA, GO:0000786=IEA, GO:0003677=IEA, GO:0042742=IEA} defense response to bacterium, nucleosome assembly nucleosome, nucleus DNA binding, protein heterodimerization activity Human UniProtKB-SubCell:SL-0191 HIST1H2BL UniProtKB UniProtKB {GO:0046982=GO_REF:0000002, GO:0006334=PMID:9439656, GO:0005634=GO_REF:0000039, GO:0000786=PMID:9439656, GO:0003677=PMID:9439656} Q99880 Histone H2B type 1-L protein 20030424 {GO:0046982=IEA, GO:0006334=NAS, GO:0005634=IEA, GO:0000786=NAS, GO:0003677=NAS} nucleosome assembly nucleosome, nucleus DNA binding, protein heterodimerization activity Human HIST1H2BM UniProtKB UniProtKB {GO:0046982=GO_REF:0000002, GO:0006334=PMID:9439656, GO:0005634=GO_REF:0000039, GO:0000786=PMID:9439656, GO:0003677=PMID:9439656} Q99879 Histone H2B type 1-M protein 20030424 {GO:0046982=IEA, GO:0006334=NAS, GO:0005634=IEA, GO:0000786=NAS, GO:0003677=NAS} nucleosome assembly nucleosome, nucleus DNA binding, protein heterodimerization activity Human HIST1H2BN UniProtKB UniProtKB {GO:0046982=GO_REF:0000002, GO:0006334=PMID:9439656, GO:0005634=GO_REF:0000039, GO:0000786=PMID:9439656, GO:0003677=PMID:9439656} Q99877 Histone H2B type 1-N protein 20030424 {GO:0046982=IEA, GO:0006334=NAS, GO:0005634=IEA, GO:0000786=NAS, GO:0003677=NAS} nucleosome assembly nucleosome, nucleus DNA binding, protein heterodimerization activity Human HIST1H2BO UniProtKB UniProtKB {GO:0046982=GO_REF:0000002, GO:0006334=PMID:1768865, GO:0005634=GO_REF:0000039, GO:0000786=PMID:1768865, GO:0003677=PMID:1768865} P23527 Histone H2B type 1-O protein 20030424 {GO:0046982=IEA, GO:0006334=NAS, GO:0005634=IEA, GO:0000786=NAS, GO:0003677=NAS} nucleosome assembly nucleosome, nucleus DNA binding, protein heterodimerization activity Human HIST1H3A BHF-UCL UniProtKB {GO:0005515=PMID:23275563, GO:0060968=PMID:16267050, GO:0046982=GO_REF:0000002, GO:0051320=PMID:16267050, GO:0007596=Reactome:REACT_604, GO:0006334=GO_REF:0000002, GO:0005654=Reactome:REACT_25371, GO:0005576=Reactome:REACT_75858, GO:0000786=GO_REF:0000037, GO:0003677=GO_REF:0000037} P68431 Histone H3.1 protein 20110311 {GO:0005515=IPI, GO:0060968=IDA, GO:0046982=IEA, GO:0051320=NAS, GO:0007596=TAS, GO:0006334=IEA, GO:0005654=TAS, GO:0005576=TAS, GO:0000786=IEA, GO:0003677=IEA} S phase, blood coagulation, nucleosome assembly, regulation of gene silencing extracellular region, nucleoplasm, nucleosome DNA binding, protein binding, protein heterodimerization activity Human HIST1H3B null null {} null null null null {} null null null HIST1H3C null null {} null null null null {} null null null HIST1H3D null null {} null null null null {} null null null HIST1H3E null null {} null null null null {} null null null HIST1H3F null null {} null null null null {} null null null HIST1H3G null null {} null null null null {} null null null HIST1H3H null null {} null null null null {} null null null HIST1H3I null null {} null null null null {} null null null HIST1H3J null null {} null null null null {} null null null HIST1H4A HPA UniProtKB {GO:0005515=PMID:21596426, GO:0046982=GO_REF:0000002, GO:0048015=PMID:15504738, GO:0005730=GO_REF:0000052, GO:0006325=PMID:15504738, GO:0006334=Reactome:REACT_22344, GO:0005634=GO_REF:0000052, GO:0005576=Reactome:REACT_75858, GO:0015629=GO_REF:0000052, GO:0003677=PMID:3035717, GO:0034080=Reactome:REACT_22186, GO:0045653=PMID:18474616, GO:0000723=Reactome:REACT_7970, GO:0005654=Reactome:REACT_22217, GO:0000786=PMID:3035717} P62805 Histone H4 protein 20120912 {GO:0005515=IPI, GO:0046982=IEA, GO:0048015=NAS, GO:0005730=IDA, GO:0006325=NAS, GO:0006334=TAS, GO:0005634=IDA, GO:0005576=TAS, GO:0015629=IDA, GO:0003677=TAS, GO:0034080=TAS, GO:0045653=IDA, GO:0000723=TAS, GO:0005654=TAS, GO:0000786=TAS} CENP-A containing nucleosome assembly at centromere, chromatin organization, negative regulation of megakaryocyte differentiation, nucleosome assembly, phosphatidylinositol-mediated signaling, telomere maintenance actin cytoskeleton, extracellular region, nucleolus, nucleoplasm, nucleosome, nucleus DNA binding, protein binding, protein heterodimerization activity Human HIST1H4B null null {} null null null null {} null null null HIST1H4C null null {} null null null null {} null null null HIST1H4D null null {} null null null null {} null null null HIST1H4E null null {} null null null null {} null null null HIST1H4F null null {} null null null null {} null null null HIST1H4G HPA UniProtKB {GO:0046982=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0006334=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0015629=GO_REF:0000052, GO:0000786=GO_REF:0000037, GO:0003677=GO_REF:0000037} Q99525 Histone H4-like protein type G protein 20120912 {GO:0046982=IEA, GO:0005730=IDA, GO:0006334=IEA, GO:0005634=IDA, GO:0015629=IDA, GO:0000786=IEA, GO:0003677=IEA} nucleosome assembly actin cytoskeleton, nucleolus, nucleosome, nucleus DNA binding, protein heterodimerization activity Human HIST1H4H null null {} null null null null {} null null null HIST1H4I null null {} null null null null {} null null null HIST1H4J null null {} null null null null {} null null null HIST1H4K null null {} null null null null {} null null null HIST1H4L null null {} null null null null {} null null null HIST2H2AA3 UniProtKB UniProtKB {GO:0046982=GO_REF:0000002, GO:0006334=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0000786=GO_REF:0000037, GO:0003677=GO_REF:0000037} Q6FI13 Histone H2A type 2-A protein 20130413 {GO:0046982=IEA, GO:0006334=IEA, GO:0005634=IEA, GO:0000786=IEA, GO:0003677=IEA} nucleosome assembly nucleosome, nucleus DNA binding, protein heterodimerization activity Human UniProtKB-SubCell:SL-0191 HIST2H2AA4 null null {} null null null null {} null null null HIST2H2AB UniProtKB UniProtKB {GO:0046982=GO_REF:0000002, GO:0006334=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0000786=GO_REF:0000037, GO:0003677=GO_REF:0000037} Q8IUE6 Histone H2A type 2-B protein 20130413 {GO:0046982=IEA, GO:0006334=IEA, GO:0005634=IEA, GO:0000786=IEA, GO:0003677=IEA} nucleosome assembly nucleosome, nucleus DNA binding, protein heterodimerization activity Human UniProtKB-SubCell:SL-0191 HIST2H2AC UniProtKB UniProtKB {GO:0046982=GO_REF:0000002, GO:0006334=GO_REF:0000029, GO:0005634=GO_REF:0000039, GO:0000786=GO_REF:0000029, GO:0003677=GO_REF:0000029} Q16777 Histone H2A type 2-C protein 20030424 {GO:0046982=IEA, GO:0006334=NAS, GO:0005634=IEA, GO:0000786=NAS, GO:0003677=NAS} nucleosome assembly nucleosome, nucleus DNA binding, protein heterodimerization activity Human HIST2H2BE UniProtKB UniProtKB {GO:0046982=GO_REF:0000002, GO:0006334=PMID:1469070, GO:0005634=GO_REF:0000039, GO:0000786=PMID:1469070, GO:0003677=PMID:1469070, GO:0042742=GO_REF:0000037} Q16778 Histone H2B type 2-E protein 20030424 {GO:0046982=IEA, GO:0006334=NAS, GO:0005634=IEA, GO:0000786=NAS, GO:0003677=NAS, GO:0042742=IEA} defense response to bacterium, nucleosome assembly nucleosome, nucleus DNA binding, protein heterodimerization activity Human HIST2H2BF UniProtKB UniProtKB {GO:0046982=GO_REF:0000002, GO:0006334=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0000786=GO_REF:0000037, GO:0003677=GO_REF:0000037} Q5QNW6 Histone H2B type 2-F protein 20130413 {GO:0046982=IEA, GO:0006334=IEA, GO:0005634=IEA, GO:0000786=IEA, GO:0003677=IEA} nucleosome assembly nucleosome, nucleus DNA binding, protein heterodimerization activity Human UniProtKB-SubCell:SL-0191 HIST2H3A IntAct UniProtKB {GO:0005515=PMID:21596426, GO:0046982=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0006334=GO_REF:0000002, GO:0005654=Reactome:REACT_25371, GO:0005576=Reactome:REACT_75858, GO:0000786=GO_REF:0000037, GO:0003677=GO_REF:0000037} Q71DI3 Histone H3.2 protein 20130415 {GO:0005515=IPI, GO:0046982=IEA, GO:0007596=TAS, GO:0006334=IEA, GO:0005654=TAS, GO:0005576=TAS, GO:0000786=IEA, GO:0003677=IEA} blood coagulation, nucleosome assembly extracellular region, nucleoplasm, nucleosome DNA binding, protein binding, protein heterodimerization activity Human UniProtKB:Q12830-4 HIST2H3C null null {} null null null null {} null null null HIST2H3D null null {} null null null null {} null null null HIST2H4A null null {} null null null null {} null null null HIST2H4B null null {} null null null null {} null null null HIST3H2A UniProtKB UniProtKB {GO:0046982=GO_REF:0000002, GO:0006334=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0000786=GO_REF:0000037, GO:0003677=GO_REF:0000037} Q7L7L0 Histone H2A type 3 protein 20130413 {GO:0046982=IEA, GO:0006334=IEA, GO:0005634=IEA, GO:0000786=IEA, GO:0003677=IEA} nucleosome assembly nucleosome, nucleus DNA binding, protein heterodimerization activity Human UniProtKB-SubCell:SL-0191 HIST3H2BB UniProtKB UniProtKB {GO:0046982=GO_REF:0000002, GO:0006334=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0000786=GO_REF:0000037, GO:0003677=GO_REF:0000037} Q8N257 Histone H2B type 3-B protein 20130413 {GO:0046982=IEA, GO:0006334=IEA, GO:0005634=IEA, GO:0000786=IEA, GO:0003677=IEA} nucleosome assembly nucleosome, nucleus DNA binding, protein heterodimerization activity Human UniProtKB-SubCell:SL-0191 HIST3H3 IntAct UniProtKB {GO:0005515=PMID:17567753, GO:0000723=Reactome:REACT_7970, GO:0046982=GO_REF:0000002, GO:0006334=GO_REF:0000029, GO:0005654=Reactome:REACT_8031, GO:0000786=GO_REF:0000029, GO:0003677=GO_REF:0000029} Q16695 Histone H3.1t protein 20130415 {GO:0005515=IPI, GO:0000723=TAS, GO:0046982=IEA, GO:0006334=NAS, GO:0005654=TAS, GO:0000786=NAS, GO:0003677=NAS} nucleosome assembly, telomere maintenance nucleoplasm, nucleosome DNA binding, protein binding, protein heterodimerization activity Human UniProtKB:O75164 HIST4H4 null null {} null null null null {} null null null HIVEP1 IntAct UniProtKB {GO:0005515=PMID:21078624, GO:0005737=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0005634=PMID:19732766, GO:0000122=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037} P15822 Zinc finger protein 40 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0008270=IEA, GO:0005634=IDA, GO:0000122=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, nucleus DNA binding, nucleic acid binding, protein binding, zinc ion binding Human UniProtKB:O00555 HIVEP2 UniProtKB UniProtKB {GO:0006355=GO_REF:0000029, GO:0005634=GO_REF:0000029, GO:0008270=GO_REF:0000002, GO:0003677=PMID:2247438, GO:0006351=GO_REF:0000037} P31629 Transcription factor HIVEP2 protein 20021104 {GO:0006355=NAS, GO:0005634=NAS, GO:0008270=IEA, GO:0003677=TAS, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human HIVEP3 MGI UniProtKB {GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0045893=PMID:15790681, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q5T1R4 Transcription factor HIVEP3 protein 20051028 {GO:0005737=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0045893=IDA, GO:0003677=IEA, GO:0006351=IEA} positive regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus DNA binding, zinc ion binding Human HJURP HPA UniProtKB {GO:0005730=GO_REF:0000052, GO:0006334=Reactome:REACT_22344, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0034080=Reactome:REACT_22186, GO:0042393=PMID:19410545, GO:0005737=GO_REF:0000052, GO:0007049=GO_REF:0000037, GO:0007059=PMID:19410544, GO:0051101=PMID:21478274, GO:0043254=PMID:21478274, GO:0000777=PMID:19410545, GO:0005654=Reactome:REACT_22217, GO:0000775=PMID:19410544} Q8NCD3 Holliday junction recognition protein protein 20101115 {GO:0005730=IDA, GO:0006334=TAS, GO:0005634=IDA, GO:0003677=IEA, GO:0034080=TAS, GO:0042393=IPI, GO:0005737=IDA, GO:0007049=IEA, GO:0007059=IMP, GO:0051101=IDA, GO:0043254=IDA, GO:0000777=IDA, GO:0005654=TAS, GO:0000775=IDA} CENP-A containing nucleosome assembly at centromere, cell cycle, chromosome segregation, nucleosome assembly, regulation of DNA binding, regulation of protein complex assembly chromosome, centromeric region, condensed chromosome kinetochore, cytoplasm, nucleolus, nucleoplasm, nucleus DNA binding, histone binding Human HK1 GOC UniProtKB {GO:0005515=PMID:22304920, GO:0001678=GO_REF:0000033, GO:0005975=Reactome:REACT_474, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005741=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0004396=PMID:3207429, GO:0055085=Reactome:REACT_19118, GO:0005524=GO_REF:0000037, GO:0006096=GO_REF:0000033, GO:0008645=Reactome:REACT_9441, GO:0005829=Reactome:REACT_1827, GO:0005739=GO_REF:0000052, GO:0004340=GO_REF:0000033, GO:0008865=GO_REF:0000033, GO:0015758=Reactome:REACT_212, GO:0016773=GO_REF:0000002, GO:0045121=GO_REF:0000019, GO:0019158=GO_REF:0000033, GO:0051156=GO_REF:0000033} P19367 Hexokinase-1 protein 20130413 {GO:0005515=IPI, GO:0001678=IBA, GO:0005975=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0005741=IEA, GO:0044281=TAS, GO:0004396=TAS, GO:0055085=TAS, GO:0005524=IEA, GO:0006096=IBA, GO:0008645=TAS, GO:0005829=TAS, GO:0005739=IDA, GO:0004340=IBA, GO:0008865=IBA, GO:0015758=TAS, GO:0016773=IEA, GO:0045121=IEA, GO:0019158=IBA, GO:0051156=IBA} carbohydrate metabolic process, cellular glucose homeostasis, glucose 6-phosphate metabolic process, glucose transport, glycolysis, hexose transport, small molecule metabolic process, transmembrane transport cytosol, membrane raft, mitochondrial outer membrane, mitochondrion, nucleolus, nucleus ATP binding, fructokinase activity, glucokinase activity, hexokinase activity, mannokinase activity, phosphotransferase activity, alcohol group as acceptor, protein binding Human PANTHER:PTN000455350 HK2 GOC UniProtKB {GO:0001678=GO_REF:0000033, GO:0005975=Reactome:REACT_474, GO:0005741=PMID:18350175, GO:0044281=Reactome:REACT_111217, GO:0004396=PMID:9278438, GO:0055085=Reactome:REACT_19118, GO:0005524=GO_REF:0000019, GO:0006096=GO_REF:0000033, GO:0005536=GO_REF:0000019, GO:0008645=Reactome:REACT_9441, GO:0005829=Reactome:REACT_1827, GO:0005739=GO_REF:0000019, GO:0004340=GO_REF:0000033, GO:0008865=GO_REF:0000033, GO:0008637=PMID:18350175, GO:0015758=Reactome:REACT_212, GO:0007595=GO_REF:0000019, GO:0046324=GO_REF:0000019, GO:0019158=GO_REF:0000033, GO:0051156=GO_REF:0000033} P52789 Hexokinase-2 protein 20130413 {GO:0001678=IBA, GO:0005975=TAS, GO:0005741=IDA, GO:0044281=TAS, GO:0004396=TAS, GO:0055085=TAS, GO:0005524=IEA, GO:0006096=IBA, GO:0005536=IEA, GO:0008645=TAS, GO:0005829=TAS, GO:0005739=IEA, GO:0004340=IBA, GO:0008865=IBA, GO:0008637=IDA, GO:0015758=TAS, GO:0007595=IEA, GO:0046324=IEA, GO:0019158=IBA, GO:0051156=IBA} apoptotic mitochondrial changes, carbohydrate metabolic process, cellular glucose homeostasis, glucose 6-phosphate metabolic process, glucose transport, glycolysis, hexose transport, lactation, regulation of glucose import, small molecule metabolic process, transmembrane transport cytosol, mitochondrial outer membrane, mitochondrion ATP binding, fructokinase activity, glucokinase activity, glucose binding, hexokinase activity, mannokinase activity Human PANTHER:PTN000455350 HK3 GOC UniProtKB {GO:0001678=GO_REF:0000033, GO:0005975=Reactome:REACT_474, GO:0042562=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0004396=PMID:8717435, GO:0055085=Reactome:REACT_19118, GO:0005524=GO_REF:0000029, GO:0006096=GO_REF:0000029, GO:0008645=Reactome:REACT_9441, GO:0005829=Reactome:REACT_1827, GO:0005739=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0004340=GO_REF:0000033, GO:0008865=GO_REF:0000033, GO:0015758=Reactome:REACT_212, GO:0016020=GO_REF:0000029, GO:0016301=GO_REF:0000038, GO:0016773=GO_REF:0000002, GO:0019158=GO_REF:0000033, GO:0019899=GO_REF:0000019, GO:0051156=GO_REF:0000033} P52790 Hexokinase-3 protein 20130413 {GO:0001678=IBA, GO:0005975=TAS, GO:0042562=IEA, GO:0044281=TAS, GO:0004396=IDA, GO:0055085=TAS, GO:0005524=NAS, GO:0006096=NAS, GO:0008645=TAS, GO:0005829=TAS, GO:0005739=IEA, GO:0043234=IEA, GO:0004340=IBA, GO:0008865=IBA, GO:0015758=TAS, GO:0016020=NAS, GO:0016301=IEA, GO:0016773=IEA, GO:0019158=IBA, GO:0019899=IEA, GO:0051156=IBA} carbohydrate metabolic process, cellular glucose homeostasis, glucose 6-phosphate metabolic process, glucose transport, glycolysis, hexose transport, small molecule metabolic process, transmembrane transport cytosol, membrane, mitochondrion, protein complex ATP binding, enzyme binding, fructokinase activity, glucokinase activity, hexokinase activity, hormone binding, kinase activity, mannokinase activity, phosphotransferase activity, alcohol group as acceptor Human PANTHER:PTN000455350 HKDC1 GOC UniProtKB {GO:0005739=GO_REF:0000052, GO:0004340=GO_REF:0000033, GO:0008865=GO_REF:0000033, GO:0001678=GO_REF:0000033, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0019158=GO_REF:0000033, GO:0051156=GO_REF:0000033, GO:0005524=GO_REF:0000037, GO:0006096=GO_REF:0000033, GO:0005829=GO_REF:0000033} Q2TB90 Putative hexokinase HKDC1 protein 20130413 {GO:0005739=IDA, GO:0004340=IBA, GO:0008865=IBA, GO:0001678=IBA, GO:0005730=IDA, GO:0005634=IDA, GO:0019158=IBA, GO:0051156=IBA, GO:0005524=IEA, GO:0006096=IBA, GO:0005829=IBA} cellular glucose homeostasis, glucose 6-phosphate metabolic process, glycolysis cytosol, mitochondrion, nucleolus, nucleus ATP binding, fructokinase activity, glucokinase activity, mannokinase activity Human PANTHER:PTN000455350 HLA-A InterPro UniProtKB {GO:0005515=PMID:12414957, GO:0002474=GO_REF:0000038, GO:0005886=Reactome:REACT_111215, GO:0019221=Reactome:REACT_25229, GO:0006955=GO_REF:0000002, GO:0060337=Reactome:REACT_25162, GO:0019882=GO_REF:0000002, GO:0030670=Reactome:REACT_111215, GO:0016032=Reactome:REACT_6185, GO:0071556=Reactome:REACT_75922, GO:0060333=Reactome:REACT_25078, GO:0012507=Reactome:REACT_75894, GO:0002480=Reactome:REACT_111168, GO:0042612=GO_REF:0000002, GO:0042590=Reactome:REACT_111119, GO:0005102=PMID:19124746, GO:0050690=Reactome:REACT_11149, GO:0000139=Reactome:REACT_75894, GO:0005887=PMID:8188325, GO:0019048=GO_REF:0000037, GO:0031901=Reactome:REACT_111222, GO:0050776=Reactome:REACT_11152, GO:0002479=Reactome:REACT_111178, GO:0016021=GO_REF:0000038, GO:0016045=PMID:22321387} Q5SRN7 HLA class I histocompatibility antigen, A-68 alpha chain protein 20130413 {GO:0005515=IPI, GO:0002474=IEA, GO:0005886=TAS, GO:0019221=TAS, GO:0006955=IEA, GO:0060337=TAS, GO:0019882=IEA, GO:0030670=TAS, GO:0016032=TAS, GO:0071556=TAS, GO:0060333=TAS, GO:0012507=TAS, GO:0002480=TAS, GO:0042612=IEA, GO:0042590=TAS, GO:0005102=IPI, GO:0050690=TAS, GO:0000139=TAS, GO:0005887=NAS, GO:0019048=IEA, GO:0031901=TAS, GO:0050776=TAS, GO:0002479=TAS, GO:0016021=IEA, GO:0016045=IMP} antigen processing and presentation, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent, antigen processing and presentation of peptide antigen via MHC class I, cytokine-mediated signaling pathway, detection of bacterium, immune response, interferon-gamma-mediated signaling pathway, regulation of defense response to virus by virus, regulation of immune response, type I interferon-mediated signaling pathway, viral reproduction, virus-host interaction ER to Golgi transport vesicle membrane, Golgi membrane, MHC class I protein complex, early endosome membrane, integral to lumenal side of endoplasmic reticulum membrane, integral to membrane, integral to plasma membrane, phagocytic vesicle membrane, plasma membrane protein binding, receptor binding Human InterPro:IPR001039 HLA-B Reactome UniProtKB {GO:0002474=Reactome:REACT_75820, GO:0005886=Reactome:REACT_147782, GO:0019221=Reactome:REACT_25229, GO:0006955=GO_REF:0000002, GO:0060337=Reactome:REACT_25162, GO:0019882=GO_REF:0000002, GO:0030670=Reactome:REACT_111215, GO:0071556=Reactome:REACT_75922, GO:0060333=Reactome:REACT_25078, GO:0012507=Reactome:REACT_75894, GO:0002480=Reactome:REACT_111168, GO:2001198=PMID:20008523, GO:0042612=GO_REF:0000037, GO:0042590=Reactome:REACT_111119, GO:0005102=PMID:20008523, GO:0006952=PMID:3011411, GO:0002667=PMID:20008523, GO:0016020=PMID:3011411, GO:0000139=Reactome:REACT_75894, GO:0005887=PMID:8420828, GO:0045087=Reactome:REACT_6802, GO:0019048=GO_REF:0000037, GO:0031901=Reactome:REACT_111222, GO:0050776=Reactome:REACT_11152, GO:0032655=PMID:20008523, GO:0002479=Reactome:REACT_111178, GO:0032675=PMID:20008523, GO:0016021=GO_REF:0000037, GO:0016045=PMID:22321387} Q95365 HLA class I histocompatibility antigen, B-38 alpha chain protein 20130213 {GO:0002474=TAS, GO:0005886=TAS, GO:0019221=TAS, GO:0006955=IEA, GO:0060337=TAS, GO:0019882=IEA, GO:0030670=TAS, GO:0071556=TAS, GO:0060333=TAS, GO:0012507=TAS, GO:0002480=TAS, GO:2001198=IMP, GO:0042612=IEA, GO:0042590=TAS, GO:0005102=IPI, GO:0006952=TAS, GO:0002667=IMP, GO:0016020=TAS, GO:0000139=TAS, GO:0005887=NAS, GO:0045087=TAS, GO:0019048=IEA, GO:0031901=TAS, GO:0050776=TAS, GO:0032655=IMP, GO:0002479=TAS, GO:0032675=IMP, GO:0016021=IEA, GO:0016045=IMP} antigen processing and presentation, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent, antigen processing and presentation of peptide antigen via MHC class I, cytokine-mediated signaling pathway, defense response, detection of bacterium, immune response, innate immune response, interferon-gamma-mediated signaling pathway, regulation of T cell anergy, regulation of dendritic cell differentiation, regulation of immune response, regulation of interleukin-12 production, regulation of interleukin-6 production, type I interferon-mediated signaling pathway, virus-host interaction ER to Golgi transport vesicle membrane, Golgi membrane, MHC class I protein complex, early endosome membrane, integral to lumenal side of endoplasmic reticulum membrane, integral to membrane, integral to plasma membrane, membrane, phagocytic vesicle membrane, plasma membrane receptor binding Human HLA-C Reactome UniProtKB {GO:0002474=Reactome:REACT_75820, GO:0012507=Reactome:REACT_75894, GO:0002480=Reactome:REACT_111168, GO:0005886=Reactome:REACT_111215, GO:0042612=GO_REF:0000037, GO:0019221=Reactome:REACT_25229, GO:0042590=Reactome:REACT_111119, GO:0005576=GO_REF:0000039, GO:0006955=PMID:2787363, GO:0060337=Reactome:REACT_25162, GO:0000139=Reactome:REACT_75894, GO:0005887=PMID:2787363, GO:0019882=GO_REF:0000002, GO:0031901=Reactome:REACT_111222, GO:0019048=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0050776=Reactome:REACT_11152, GO:0030670=Reactome:REACT_111215, GO:0071556=Reactome:REACT_75922, GO:0002479=Reactome:REACT_111178, GO:0016021=GO_REF:0000038, GO:0060333=Reactome:REACT_25078} Q9TNN7 HLA class I histocompatibility antigen, Cw-5 alpha chain protein 20101103 {GO:0002474=TAS, GO:0012507=TAS, GO:0002480=TAS, GO:0005886=TAS, GO:0042612=IEA, GO:0019221=TAS, GO:0042590=TAS, GO:0005576=IEA, GO:0006955=NAS, GO:0060337=TAS, GO:0000139=TAS, GO:0005887=NAS, GO:0019882=IEA, GO:0031901=TAS, GO:0019048=IEA, GO:0045087=TAS, GO:0050776=TAS, GO:0030670=TAS, GO:0071556=TAS, GO:0002479=TAS, GO:0016021=IEA, GO:0060333=TAS} antigen processing and presentation, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent, antigen processing and presentation of peptide antigen via MHC class I, cytokine-mediated signaling pathway, immune response, innate immune response, interferon-gamma-mediated signaling pathway, regulation of immune response, type I interferon-mediated signaling pathway, virus-host interaction ER to Golgi transport vesicle membrane, Golgi membrane, MHC class I protein complex, early endosome membrane, extracellular region, integral to lumenal side of endoplasmic reticulum membrane, integral to membrane, integral to plasma membrane, phagocytic vesicle membrane, plasma membrane Human HLA-DMA UniProtKB UniProtKB {GO:0048839=GO_REF:0000019, GO:0016064=GO_REF:0000019, GO:0002504=GO_REF:0000038, GO:0005771=GO_REF:0000019, GO:0042613=GO_REF:0000038, GO:0005765=Reactome:REACT_121161, GO:0015031=GO_REF:0000019, GO:0045059=GO_REF:0000019, GO:0019886=Reactome:REACT_121399, GO:0006955=GO_REF:0000002, GO:0006461=GO_REF:0000019, GO:0050778=GO_REF:0000019, GO:0031902=GO_REF:0000039, GO:0051085=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0010008=GO_REF:0000019, GO:0045582=GO_REF:0000019} Q5SP00 HLA class II histocompatibility antigen, DM alpha chain protein 20130413 {GO:0048839=IEA, GO:0016064=IEA, GO:0002504=IEA, GO:0005771=IEA, GO:0042613=IEA, GO:0005765=TAS, GO:0015031=IEA, GO:0045059=IEA, GO:0019886=TAS, GO:0006955=IEA, GO:0006461=IEA, GO:0050778=IEA, GO:0031902=IEA, GO:0051085=IEA, GO:0016021=IEA, GO:0010008=IEA, GO:0045582=IEA} antigen processing and presentation of exogenous peptide antigen via MHC class II, antigen processing and presentation of peptide or polysaccharide antigen via MHC class II, chaperone mediated protein folding requiring cofactor, immune response, immunoglobulin mediated immune response, inner ear development, positive regulation of T cell differentiation, positive regulation of immune response, positive thymic T cell selection, protein complex assembly, protein transport MHC class II protein complex, endosome membrane, integral to membrane, late endosome membrane, lysosomal membrane, multivesicular body Human UniProtKB-KW:KW-0491 HLA-DMB Reactome UniProtKB {GO:0019886=Reactome:REACT_121399, GO:0006955=GO_REF:0000002, GO:0002504=GO_REF:0000038, GO:0031902=GO_REF:0000039, GO:0042613=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005765=Reactome:REACT_121161} P28068 HLA class II histocompatibility antigen, DM beta chain protein 20120221 {GO:0019886=TAS, GO:0006955=IEA, GO:0002504=IEA, GO:0031902=IEA, GO:0042613=IEA, GO:0016021=IEA, GO:0005765=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, antigen processing and presentation of peptide or polysaccharide antigen via MHC class II, immune response MHC class II protein complex, integral to membrane, late endosome membrane, lysosomal membrane Human HLA-DOA Reactome UniProtKB {GO:0019886=Reactome:REACT_121399, GO:0006955=GO_REF:0000002, GO:0005886=PMID:3000765, GO:0002504=GO_REF:0000038, GO:0045580=GO_REF:0000019, GO:0042613=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005765=Reactome:REACT_121161, GO:0032395=PMID:3000765, GO:0010008=GO_REF:0000039} P06340 HLA class II histocompatibility antigen, DO alpha chain protein 20120221 {GO:0019886=TAS, GO:0006955=IEA, GO:0005886=TAS, GO:0002504=IEA, GO:0045580=IEA, GO:0042613=IEA, GO:0016021=IEA, GO:0005765=TAS, GO:0032395=TAS, GO:0010008=IEA} antigen processing and presentation of exogenous peptide antigen via MHC class II, antigen processing and presentation of peptide or polysaccharide antigen via MHC class II, immune response, regulation of T cell differentiation MHC class II protein complex, endosome membrane, integral to membrane, lysosomal membrane, plasma membrane MHC class II receptor activity Human HLA-DOB Reactome UniProtKB {GO:0019886=Reactome:REACT_121399, GO:0006955=GO_REF:0000002, GO:0002504=GO_REF:0000038, GO:0042613=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005765=Reactome:REACT_121161, GO:0005764=PMID:8890155, GO:0032395=PMID:2998758, GO:0010008=GO_REF:0000039} P13765 HLA class II histocompatibility antigen, DO beta chain protein 20120221 {GO:0019886=TAS, GO:0006955=IEA, GO:0002504=IEA, GO:0042613=IEA, GO:0016021=IEA, GO:0005765=TAS, GO:0005764=IDA, GO:0032395=TAS, GO:0010008=IEA} antigen processing and presentation of exogenous peptide antigen via MHC class II, antigen processing and presentation of peptide or polysaccharide antigen via MHC class II, immune response MHC class II protein complex, endosome membrane, integral to membrane, lysosomal membrane, lysosome MHC class II receptor activity Human HLA-DPA1 Reactome UniProtKB {GO:0050852=Reactome:REACT_12526, GO:0012507=Reactome:REACT_121121, GO:0005886=Reactome:REACT_121063, GO:0002504=GO_REF:0000038, GO:0031295=Reactome:REACT_19344, GO:0019221=Reactome:REACT_25229, GO:0042613=GO_REF:0000037, GO:0005765=Reactome:REACT_121306, GO:0032588=Reactome:REACT_121309, GO:0030666=Reactome:REACT_121177, GO:0019886=Reactome:REACT_121399, GO:0006955=PMID:2461352, GO:0071346=PMID:8568247, GO:0000139=Reactome:REACT_121309, GO:0005887=PMID:2461352, GO:0071556=Reactome:REACT_121334, GO:0016021=GO_REF:0000038, GO:0030669=Reactome:REACT_121177, GO:0032395=PMID:2461352, GO:0010008=GO_REF:0000039, GO:0060333=Reactome:REACT_25078, GO:0030658=Reactome:REACT_121063} P20036 HLA class II histocompatibility antigen, DP alpha 1 chain protein 20120221 {GO:0050852=TAS, GO:0012507=TAS, GO:0005886=TAS, GO:0002504=IEA, GO:0031295=TAS, GO:0019221=TAS, GO:0042613=IEA, GO:0005765=TAS, GO:0032588=TAS, GO:0030666=TAS, GO:0019886=TAS, GO:0006955=NAS, GO:0071346=IDA, GO:0000139=TAS, GO:0005887=NAS, GO:0071556=TAS, GO:0016021=IEA, GO:0030669=TAS, GO:0032395=NAS, GO:0010008=IEA, GO:0060333=TAS, GO:0030658=TAS} T cell costimulation, T cell receptor signaling pathway, antigen processing and presentation of exogenous peptide antigen via MHC class II, antigen processing and presentation of peptide or polysaccharide antigen via MHC class II, cellular response to interferon-gamma, cytokine-mediated signaling pathway, immune response, interferon-gamma-mediated signaling pathway ER to Golgi transport vesicle membrane, Golgi membrane, MHC class II protein complex, clathrin-coated endocytic vesicle membrane, endocytic vesicle membrane, endosome membrane, integral to lumenal side of endoplasmic reticulum membrane, integral to membrane, integral to plasma membrane, lysosomal membrane, plasma membrane, trans-Golgi network membrane, transport vesicle membrane MHC class II receptor activity Human HLA-DPB1 UniProtKB UniProtKB {GO:0050852=Reactome:REACT_12526, GO:0012507=Reactome:REACT_121121, GO:0005886=Reactome:REACT_121063, GO:0002504=GO_REF:0000038, GO:0031295=Reactome:REACT_19344, GO:0019221=Reactome:REACT_25229, GO:0042613=GO_REF:0000038, GO:0005765=Reactome:REACT_121306, GO:0032588=Reactome:REACT_121309, GO:0030666=Reactome:REACT_121177, GO:0019886=Reactome:REACT_121399, GO:0006955=GO_REF:0000002, GO:0000139=Reactome:REACT_121309, GO:0019882=GO_REF:0000002, GO:0071556=Reactome:REACT_121334, GO:0016021=GO_REF:0000038, GO:0030669=Reactome:REACT_121177, GO:0010008=GO_REF:0000039, GO:0060333=Reactome:REACT_25078, GO:0030658=Reactome:REACT_121063} Q5SQ72 HLA class II histocompatibility antigen, DP beta 1 chain protein 20130413 {GO:0050852=TAS, GO:0012507=TAS, GO:0005886=TAS, GO:0002504=IEA, GO:0031295=TAS, GO:0019221=TAS, GO:0042613=IEA, GO:0005765=TAS, GO:0032588=TAS, GO:0030666=TAS, GO:0019886=TAS, GO:0006955=IEA, GO:0000139=TAS, GO:0019882=IEA, GO:0071556=TAS, GO:0016021=IEA, GO:0030669=TAS, GO:0010008=IEA, GO:0060333=TAS, GO:0030658=TAS} T cell costimulation, T cell receptor signaling pathway, antigen processing and presentation, antigen processing and presentation of exogenous peptide antigen via MHC class II, antigen processing and presentation of peptide or polysaccharide antigen via MHC class II, cytokine-mediated signaling pathway, immune response, interferon-gamma-mediated signaling pathway ER to Golgi transport vesicle membrane, Golgi membrane, MHC class II protein complex, clathrin-coated endocytic vesicle membrane, endocytic vesicle membrane, endosome membrane, integral to lumenal side of endoplasmic reticulum membrane, integral to membrane, lysosomal membrane, plasma membrane, trans-Golgi network membrane, transport vesicle membrane Human UniProtKB-KW:KW-0491 HLA-DQA1 Reactome UniProtKB {GO:0050852=Reactome:REACT_12526, GO:0012507=Reactome:REACT_121121, GO:0005886=Reactome:REACT_121063, GO:0002504=GO_REF:0000038, GO:0031295=Reactome:REACT_19344, GO:0019221=Reactome:REACT_25229, GO:0042613=GO_REF:0000037, GO:0005765=Reactome:REACT_121306, GO:0032588=Reactome:REACT_121309, GO:0030666=Reactome:REACT_121177, GO:0019886=Reactome:REACT_121399, GO:0006955=PMID:3584986, GO:0000139=Reactome:REACT_121309, GO:0005887=PMID:3584986, GO:0071556=Reactome:REACT_121334, GO:0016021=GO_REF:0000038, GO:0030669=Reactome:REACT_121177, GO:0032395=PMID:3584986, GO:0010008=GO_REF:0000039, GO:0060333=Reactome:REACT_25078, GO:0030658=Reactome:REACT_121063} P01909 HLA class II histocompatibility antigen, DQ alpha 1 chain protein 20120221 {GO:0050852=TAS, GO:0012507=TAS, GO:0005886=TAS, GO:0002504=IEA, GO:0031295=TAS, GO:0019221=TAS, GO:0042613=IEA, GO:0005765=TAS, GO:0032588=TAS, GO:0030666=TAS, GO:0019886=TAS, GO:0006955=NAS, GO:0000139=TAS, GO:0005887=NAS, GO:0071556=TAS, GO:0016021=IEA, GO:0030669=TAS, GO:0032395=NAS, GO:0010008=IEA, GO:0060333=TAS, GO:0030658=TAS} T cell costimulation, T cell receptor signaling pathway, antigen processing and presentation of exogenous peptide antigen via MHC class II, antigen processing and presentation of peptide or polysaccharide antigen via MHC class II, cytokine-mediated signaling pathway, immune response, interferon-gamma-mediated signaling pathway ER to Golgi transport vesicle membrane, Golgi membrane, MHC class II protein complex, clathrin-coated endocytic vesicle membrane, endocytic vesicle membrane, endosome membrane, integral to lumenal side of endoplasmic reticulum membrane, integral to membrane, integral to plasma membrane, lysosomal membrane, plasma membrane, trans-Golgi network membrane, transport vesicle membrane MHC class II receptor activity Human HLA-DQA2 Reactome UniProtKB {GO:0050852=Reactome:REACT_12526, GO:0012507=Reactome:REACT_121121, GO:0005886=Reactome:REACT_121063, GO:0031295=Reactome:REACT_19344, GO:0019221=Reactome:REACT_25229, GO:0042613=GO_REF:0000037, GO:0005765=Reactome:REACT_121306, GO:0032588=Reactome:REACT_121309, GO:0030666=Reactome:REACT_121177, GO:0019886=Reactome:REACT_121399, GO:0006955=PMID:3036828, GO:0000139=Reactome:REACT_121309, GO:0005887=PMID:3036828, GO:0071556=Reactome:REACT_121334, GO:0030669=Reactome:REACT_121177, GO:0032395=PMID:3036828, GO:0010008=GO_REF:0000039, GO:0060333=Reactome:REACT_25078, GO:0030658=Reactome:REACT_121063} P01906 HLA class II histocompatibility antigen, DQ alpha 2 chain protein 20120221 {GO:0050852=TAS, GO:0012507=TAS, GO:0005886=TAS, GO:0031295=TAS, GO:0019221=TAS, GO:0042613=IEA, GO:0005765=TAS, GO:0032588=TAS, GO:0030666=TAS, GO:0019886=TAS, GO:0006955=NAS, GO:0000139=TAS, GO:0005887=NAS, GO:0071556=TAS, GO:0030669=TAS, GO:0032395=NAS, GO:0010008=IEA, GO:0060333=TAS, GO:0030658=TAS} T cell costimulation, T cell receptor signaling pathway, antigen processing and presentation of exogenous peptide antigen via MHC class II, cytokine-mediated signaling pathway, immune response, interferon-gamma-mediated signaling pathway ER to Golgi transport vesicle membrane, Golgi membrane, MHC class II protein complex, clathrin-coated endocytic vesicle membrane, endocytic vesicle membrane, endosome membrane, integral to lumenal side of endoplasmic reticulum membrane, integral to plasma membrane, lysosomal membrane, plasma membrane, trans-Golgi network membrane, transport vesicle membrane MHC class II receptor activity Human HLA-DQB1 UniProtKB UniProtKB {GO:0050852=Reactome:REACT_12526, GO:0012507=Reactome:REACT_121121, GO:0005886=Reactome:REACT_121063, GO:0002504=GO_REF:0000038, GO:0031295=Reactome:REACT_19344, GO:0019221=Reactome:REACT_25229, GO:0042613=GO_REF:0000038, GO:0005765=Reactome:REACT_121306, GO:0032588=Reactome:REACT_121309, GO:0030666=Reactome:REACT_121177, GO:0019886=Reactome:REACT_121399, GO:0006955=GO_REF:0000002, GO:0016020=PMID:2998758, GO:0000139=Reactome:REACT_121309, GO:0002381=PMID:17050030, GO:0071556=Reactome:REACT_121334, GO:0016021=GO_REF:0000038, GO:0030669=Reactome:REACT_121177, GO:0032395=PMID:2998758, GO:0010008=GO_REF:0000039, GO:0060333=Reactome:REACT_25078, GO:0030658=Reactome:REACT_121063, GO:0002455=PMID:17050030} Q5Y7D6 MHC class II antigen protein 20130413 {GO:0050852=TAS, GO:0012507=TAS, GO:0005886=TAS, GO:0002504=IEA, GO:0031295=TAS, GO:0019221=TAS, GO:0042613=IEA, GO:0005765=TAS, GO:0032588=TAS, GO:0030666=TAS, GO:0019886=TAS, GO:0006955=IEA, GO:0016020=NAS, GO:0000139=TAS, GO:0002381=IDA, GO:0071556=TAS, GO:0016021=IEA, GO:0030669=TAS, GO:0032395=NAS, GO:0010008=IEA, GO:0060333=TAS, GO:0030658=TAS, GO:0002455=IDA} T cell costimulation, T cell receptor signaling pathway, antigen processing and presentation of exogenous peptide antigen via MHC class II, antigen processing and presentation of peptide or polysaccharide antigen via MHC class II, cytokine-mediated signaling pathway, humoral immune response mediated by circulating immunoglobulin, immune response, immunoglobulin production involved in immunoglobulin mediated immune response, interferon-gamma-mediated signaling pathway ER to Golgi transport vesicle membrane, Golgi membrane, MHC class II protein complex, clathrin-coated endocytic vesicle membrane, endocytic vesicle membrane, endosome membrane, integral to lumenal side of endoplasmic reticulum membrane, integral to membrane, lysosomal membrane, membrane, plasma membrane, trans-Golgi network membrane, transport vesicle membrane MHC class II receptor activity Human UniProtKB-KW:KW-0491 HLA-DQB2 UniProtKB UniProtKB {GO:0050852=Reactome:REACT_12526, GO:0012507=Reactome:REACT_121121, GO:0005886=Reactome:REACT_121063, GO:0002504=GO_REF:0000038, GO:0031295=Reactome:REACT_19344, GO:0019221=Reactome:REACT_25229, GO:0042613=GO_REF:0000038, GO:0005765=Reactome:REACT_121306, GO:0032588=Reactome:REACT_121309, GO:0030666=Reactome:REACT_121177, GO:0019886=Reactome:REACT_121399, GO:0006955=GO_REF:0000002, GO:0000139=Reactome:REACT_121309, GO:0071556=Reactome:REACT_121334, GO:0016021=GO_REF:0000038, GO:0030669=Reactome:REACT_121177, GO:0032395=PMID:2564844, GO:0010008=GO_REF:0000039, GO:0060333=Reactome:REACT_25078, GO:0030658=Reactome:REACT_121063} Q5SR05 HLA class II histocompatibility antigen, DQ beta 2 chain protein 20130413 {GO:0050852=TAS, GO:0012507=TAS, GO:0005886=TAS, GO:0002504=IEA, GO:0031295=TAS, GO:0019221=TAS, GO:0042613=IEA, GO:0005765=TAS, GO:0032588=TAS, GO:0030666=TAS, GO:0019886=TAS, GO:0006955=IEA, GO:0000139=TAS, GO:0071556=TAS, GO:0016021=IEA, GO:0030669=TAS, GO:0032395=NAS, GO:0010008=IEA, GO:0060333=TAS, GO:0030658=TAS} T cell costimulation, T cell receptor signaling pathway, antigen processing and presentation of exogenous peptide antigen via MHC class II, antigen processing and presentation of peptide or polysaccharide antigen via MHC class II, cytokine-mediated signaling pathway, immune response, interferon-gamma-mediated signaling pathway ER to Golgi transport vesicle membrane, Golgi membrane, MHC class II protein complex, clathrin-coated endocytic vesicle membrane, endocytic vesicle membrane, endosome membrane, integral to lumenal side of endoplasmic reticulum membrane, integral to membrane, lysosomal membrane, plasma membrane, trans-Golgi network membrane, transport vesicle membrane MHC class II receptor activity Human UniProtKB-KW:KW-0491 HLA-DRA UniProtKB UniProtKB {GO:0050852=Reactome:REACT_12526, GO:0012507=Reactome:REACT_121121, GO:0005886=Reactome:REACT_121063, GO:0002504=GO_REF:0000038, GO:0031295=Reactome:REACT_19344, GO:0019221=Reactome:REACT_25229, GO:0042613=GO_REF:0000038, GO:0005765=Reactome:REACT_121306, GO:0032588=Reactome:REACT_121309, GO:0005764=PMID:8890155, GO:0030666=Reactome:REACT_121177, GO:0019886=Reactome:REACT_121399, GO:0006955=GO_REF:0000002, GO:0000139=Reactome:REACT_121309, GO:0019882=GO_REF:0000002, GO:0005887=PMID:6812963, GO:0031902=PMID:19117940, GO:0071556=Reactome:REACT_121334, GO:0016021=GO_REF:0000038, GO:0030669=Reactome:REACT_121177, GO:0032395=PMID:6812963, GO:0060333=Reactome:REACT_25078, GO:0030658=Reactome:REACT_121063} Q5SP06 HLA class II histocompatibility antigen, DR alpha chain protein 20130413 {GO:0050852=TAS, GO:0012507=TAS, GO:0005886=TAS, GO:0002504=IEA, GO:0031295=TAS, GO:0019221=TAS, GO:0042613=IEA, GO:0005765=TAS, GO:0032588=TAS, GO:0005764=IDA, GO:0030666=TAS, GO:0019886=TAS, GO:0006955=IEA, GO:0000139=TAS, GO:0019882=IEA, GO:0005887=NAS, GO:0031902=IDA, GO:0071556=TAS, GO:0016021=IEA, GO:0030669=TAS, GO:0032395=NAS, GO:0060333=TAS, GO:0030658=TAS} T cell costimulation, T cell receptor signaling pathway, antigen processing and presentation, antigen processing and presentation of exogenous peptide antigen via MHC class II, antigen processing and presentation of peptide or polysaccharide antigen via MHC class II, cytokine-mediated signaling pathway, immune response, interferon-gamma-mediated signaling pathway ER to Golgi transport vesicle membrane, Golgi membrane, MHC class II protein complex, clathrin-coated endocytic vesicle membrane, endocytic vesicle membrane, integral to lumenal side of endoplasmic reticulum membrane, integral to membrane, integral to plasma membrane, late endosome membrane, lysosomal membrane, lysosome, plasma membrane, trans-Golgi network membrane, transport vesicle membrane MHC class II receptor activity Human UniProtKB-KW:KW-0491 HLA-DRB1 Reactome UniProtKB {GO:0005515=PMID:15795121, GO:0002437=GO_REF:0000024, GO:0050852=Reactome:REACT_12526, GO:0005886=Reactome:REACT_121063, GO:0019221=Reactome:REACT_25229, GO:0031295=Reactome:REACT_19344, GO:0042088=GO_REF:0000024, GO:0005765=Reactome:REACT_121306, GO:0042130=GO_REF:0000024, GO:0019886=Reactome:REACT_121399, GO:0006955=GO_REF:0000024, GO:0002381=GO_REF:0000024, GO:0042605=GO_REF:0000024, GO:2001179=GO_REF:0000024, GO:0071556=Reactome:REACT_121334, GO:0032689=GO_REF:0000024, GO:0030658=Reactome:REACT_121063, GO:0060333=Reactome:REACT_25078, GO:0012507=Reactome:REACT_121121, GO:0051262=GO_REF:0000024, GO:0035774=GO_REF:0000024, GO:0042613=GO_REF:0000037, GO:0032588=Reactome:REACT_121309, GO:0030666=Reactome:REACT_121177, GO:0007165=PMID:8775462, GO:0000139=Reactome:REACT_121309, GO:0016020=PMID:3129499, GO:0005887=PMID:3456344, GO:0031902=PMID:18305173, GO:0032673=GO_REF:0000024, GO:0032395=PMID:3129499, GO:0030669=Reactome:REACT_121177, GO:0016045=GO_REF:0000024, GO:0009897=GO_REF:0000024, GO:0002455=GO_REF:0000024} Q9TQE0 HLA class II histocompatibility antigen, DRB1-9 beta chain protein 20130301 {GO:0005515=IPI, GO:0002437=ISS, GO:0050852=TAS, GO:0005886=TAS, GO:0019221=TAS, GO:0031295=TAS, GO:0042088=ISS, GO:0005765=TAS, GO:0042130=ISS, GO:0019886=TAS, GO:0006955=ISS, GO:0002381=ISS, GO:0042605=ISS, GO:2001179=ISS, GO:0071556=TAS, GO:0032689=ISS, GO:0030658=TAS, GO:0060333=TAS, GO:0012507=TAS, GO:0051262=ISS, GO:0035774=ISS, GO:0042613=IEA, GO:0032588=TAS, GO:0030666=TAS, GO:0007165=NAS, GO:0000139=TAS, GO:0016020=NAS, GO:0005887=TAS, GO:0031902=IDA, GO:0032673=ISS, GO:0032395=NAS, GO:0030669=TAS, GO:0016045=ISS, GO:0009897=ISS, GO:0002455=ISS} T cell costimulation, T cell receptor signaling pathway, T-helper 1 type immune response, antigen processing and presentation of exogenous peptide antigen via MHC class II, cytokine-mediated signaling pathway, detection of bacterium, humoral immune response mediated by circulating immunoglobulin, immune response, immunoglobulin production involved in immunoglobulin mediated immune response, inflammatory response to antigenic stimulus, interferon-gamma-mediated signaling pathway, negative regulation of T cell proliferation, negative regulation of interferon-gamma production, positive regulation of insulin secretion involved in cellular response to glucose stimulus, protein tetramerization, regulation of interleukin-10 secretion, regulation of interleukin-4 production, signal transduction ER to Golgi transport vesicle membrane, Golgi membrane, MHC class II protein complex, clathrin-coated endocytic vesicle membrane, endocytic vesicle membrane, external side of plasma membrane, integral to lumenal side of endoplasmic reticulum membrane, integral to plasma membrane, late endosome membrane, lysosomal membrane, membrane, plasma membrane, trans-Golgi network membrane, transport vesicle membrane MHC class II receptor activity, peptide antigen binding, protein binding Human HLA-DRB5 Reactome UniProtKB {GO:0050852=Reactome:REACT_12526, GO:0012507=Reactome:REACT_121121, GO:0005886=Reactome:REACT_121063, GO:0019221=Reactome:REACT_25229, GO:0031295=Reactome:REACT_19344, GO:0042613=GO_REF:0000037, GO:0005765=Reactome:REACT_121306, GO:0032588=Reactome:REACT_121309, GO:0030666=Reactome:REACT_121177, GO:0019886=Reactome:REACT_121399, GO:0000139=Reactome:REACT_121309, GO:0031902=PMID:18305173, GO:0071556=Reactome:REACT_121334, GO:0030669=Reactome:REACT_121177, GO:0060333=Reactome:REACT_25078, GO:0030658=Reactome:REACT_121063} Q30154 HLA class II histocompatibility antigen, DR beta 5 chain protein 20120221 {GO:0050852=TAS, GO:0012507=TAS, GO:0005886=TAS, GO:0019221=TAS, GO:0031295=TAS, GO:0042613=IEA, GO:0005765=TAS, GO:0032588=TAS, GO:0030666=TAS, GO:0019886=TAS, GO:0000139=TAS, GO:0031902=IDA, GO:0071556=TAS, GO:0030669=TAS, GO:0060333=TAS, GO:0030658=TAS} T cell costimulation, T cell receptor signaling pathway, antigen processing and presentation of exogenous peptide antigen via MHC class II, cytokine-mediated signaling pathway, interferon-gamma-mediated signaling pathway ER to Golgi transport vesicle membrane, Golgi membrane, MHC class II protein complex, clathrin-coated endocytic vesicle membrane, endocytic vesicle membrane, integral to lumenal side of endoplasmic reticulum membrane, late endosome membrane, lysosomal membrane, plasma membrane, trans-Golgi network membrane, transport vesicle membrane Human HLA-E InterPro UniProtKB {GO:0002474=Reactome:REACT_75820, GO:0012507=Reactome:REACT_75894, GO:0002480=Reactome:REACT_111168, GO:0005886=Reactome:REACT_147879, GO:0042612=GO_REF:0000002, GO:0019221=Reactome:REACT_25229, GO:0042590=Reactome:REACT_111119, GO:0006955=GO_REF:0000002, GO:0060337=Reactome:REACT_25162, GO:0000139=Reactome:REACT_75894, GO:0019882=GO_REF:0000002, GO:0031901=Reactome:REACT_111222, GO:0045087=Reactome:REACT_6802, GO:0050776=Reactome:REACT_11152, GO:0030670=Reactome:REACT_111215, GO:0071556=Reactome:REACT_75922, GO:0002479=Reactome:REACT_111178, GO:0060333=Reactome:REACT_25078} Q6DU44 HLA-E protein protein 20130413 {GO:0002474=TAS, GO:0012507=TAS, GO:0002480=TAS, GO:0005886=TAS, GO:0042612=IEA, GO:0019221=TAS, GO:0042590=TAS, GO:0006955=IEA, GO:0060337=TAS, GO:0000139=TAS, GO:0019882=IEA, GO:0031901=TAS, GO:0045087=TAS, GO:0050776=TAS, GO:0030670=TAS, GO:0071556=TAS, GO:0002479=TAS, GO:0060333=TAS} antigen processing and presentation, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent, antigen processing and presentation of peptide antigen via MHC class I, cytokine-mediated signaling pathway, immune response, innate immune response, interferon-gamma-mediated signaling pathway, regulation of immune response, type I interferon-mediated signaling pathway ER to Golgi transport vesicle membrane, Golgi membrane, MHC class I protein complex, early endosome membrane, integral to lumenal side of endoplasmic reticulum membrane, phagocytic vesicle membrane, plasma membrane Human InterPro:IPR001039 HLA-F InterPro UniProtKB {GO:0002474=Reactome:REACT_75820, GO:0012507=Reactome:REACT_75894, GO:0002480=Reactome:REACT_111168, GO:0005886=Reactome:REACT_111215, GO:0042612=GO_REF:0000002, GO:0019221=Reactome:REACT_25229, GO:0042590=Reactome:REACT_111119, GO:0006955=GO_REF:0000002, GO:0060337=Reactome:REACT_25162, GO:0000139=Reactome:REACT_75894, GO:0019882=GO_REF:0000002, GO:0031901=Reactome:REACT_111222, GO:0050776=Reactome:REACT_11152, GO:0030670=Reactome:REACT_111215, GO:0071556=Reactome:REACT_75922, GO:0002479=Reactome:REACT_111178, GO:0060333=Reactome:REACT_25078} Q5SPT7 HLA class I histocompatibility antigen, alpha chain F protein 20130413 {GO:0002474=TAS, GO:0012507=TAS, GO:0002480=TAS, GO:0005886=TAS, GO:0042612=IEA, GO:0019221=TAS, GO:0042590=TAS, GO:0006955=IEA, GO:0060337=TAS, GO:0000139=TAS, GO:0019882=IEA, GO:0031901=TAS, GO:0050776=TAS, GO:0030670=TAS, GO:0071556=TAS, GO:0002479=TAS, GO:0060333=TAS} antigen processing and presentation, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent, antigen processing and presentation of peptide antigen via MHC class I, cytokine-mediated signaling pathway, immune response, interferon-gamma-mediated signaling pathway, regulation of immune response, type I interferon-mediated signaling pathway ER to Golgi transport vesicle membrane, Golgi membrane, MHC class I protein complex, early endosome membrane, integral to lumenal side of endoplasmic reticulum membrane, phagocytic vesicle membrane, plasma membrane Human InterPro:IPR001039 HLA-G InterPro UniProtKB {GO:0002474=Reactome:REACT_75820, GO:0005886=Reactome:REACT_111215, GO:0019221=Reactome:REACT_25229, GO:0032735=PMID:20702625, GO:0042803=PMID:18550825, GO:0042130=PMID:20702625, GO:0006955=GO_REF:0000002, GO:0060337=Reactome:REACT_25162, GO:0019882=GO_REF:0000002, GO:0030670=Reactome:REACT_111215, GO:0071556=Reactome:REACT_75922, GO:2001199=PMID:20702625, GO:0060333=Reactome:REACT_25078, GO:0012507=Reactome:REACT_75894, GO:0002480=Reactome:REACT_111168, GO:0042612=GO_REF:0000002, GO:0042590=Reactome:REACT_111119, GO:0005102=PMID:20702625, GO:0002666=PMID:20448110, GO:0006968=PMID:9539768, GO:0002767=PMID:20702625, GO:0000139=Reactome:REACT_75894, GO:0031901=Reactome:REACT_111222, GO:0050776=Reactome:REACT_11152, GO:0002479=Reactome:REACT_111178, GO:0045591=PMID:20448110} Q5RJ85 HLA class I histocompatibility antigen, alpha chain G protein 20130413 {GO:0002474=TAS, GO:0005886=TAS, GO:0019221=TAS, GO:0032735=IDA, GO:0042803=NAS, GO:0042130=IDA, GO:0006955=IEA, GO:0060337=TAS, GO:0019882=IEA, GO:0030670=TAS, GO:0071556=TAS, GO:2001199=IDA, GO:0060333=TAS, GO:0012507=TAS, GO:0002480=TAS, GO:0042612=IEA, GO:0042590=TAS, GO:0005102=IPI, GO:0002666=IMP, GO:0006968=TAS, GO:0002767=IDA, GO:0000139=TAS, GO:0031901=TAS, GO:0050776=TAS, GO:0002479=TAS, GO:0045591=IMP} antigen processing and presentation, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent, antigen processing and presentation of peptide antigen via MHC class I, cellular defense response, cytokine-mediated signaling pathway, immune response, immune response-inhibiting cell surface receptor signaling pathway, interferon-gamma-mediated signaling pathway, negative regulation of T cell proliferation, negative regulation of dendritic cell differentiation, positive regulation of T cell tolerance induction, positive regulation of interleukin-12 production, positive regulation of regulatory T cell differentiation, regulation of immune response, type I interferon-mediated signaling pathway ER to Golgi transport vesicle membrane, Golgi membrane, MHC class I protein complex, early endosome membrane, integral to lumenal side of endoplasmic reticulum membrane, phagocytic vesicle membrane, plasma membrane protein homodimerization activity, receptor binding Human InterPro:IPR001039 HLCS HPA UniProtKB {GO:0009305=PMID:7842009, GO:0004080=PMID:7842009, GO:0008283=PMID:18429047, GO:0016570=PMID:14613969, GO:0071110=PMID:14613969, GO:0005524=GO_REF:0000037, GO:0016363=PMID:14613969, GO:0042803=GO_REF:0000019, GO:0070781=PMID:17904341, GO:0005829=PMID:9630604, GO:0005739=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0018271=PMID:18429047, GO:0005652=PMID:14613969, GO:0009374=PMID:14613969, GO:0004078=GO_REF:0000003, GO:0004077=GO_REF:0000003, GO:0019899=PMID:19157941, GO:0000785=PMID:14613969, GO:0004079=GO_REF:0000003, GO:0006464=GO_REF:0000002} P50747 Biotin--protein ligase protein 20090616 {GO:0009305=IDA, GO:0004080=IDA, GO:0008283=IMP, GO:0016570=IDA, GO:0071110=IDA, GO:0005524=IEA, GO:0016363=IDA, GO:0042803=IEA, GO:0070781=IDA, GO:0005829=IDA, GO:0005739=IEA, GO:0005737=IDA, GO:0018271=IMP, GO:0005652=IDA, GO:0009374=IDA, GO:0004078=IEA, GO:0004077=IEA, GO:0019899=IPI, GO:0000785=IDA, GO:0004079=IEA, GO:0006464=IEA} cell proliferation, cellular protein modification process, histone biotinylation, histone modification, protein biotinylation, response to biotin chromatin, cytoplasm, cytosol, mitochondrion, nuclear lamina, nuclear matrix "ATP binding, biotin binding, biotin-acetyl-CoA-carboxylase"" ligase activity, biotin-""methylcrotonoyl-CoA-carboxylase"" ligase activity, biotin-""methylmalonyl-CoA-carboxytransferase"" ligase activity, biotin-""propionyl-CoA-carboxylase (ATP-hydrolyzing)"" ligase activity, biotin-protein ligase activity, enzyme binding, protein homodimerization activity""" Human HLF PINC UniProtKB {GO:0043565=GO_REF:0000002, GO:0003690=PMID:1386162, GO:0003700=GO_REF:0000002, GO:0006366=PMID:8639829, GO:0007275=PMID:1386162, GO:0005634=GO_REF:0000039, GO:0048511=GO_REF:0000037, GO:0003677=PMID:8639829} Q16534 Hepatic leukemia factor protein 20030904 {GO:0043565=IEA, GO:0003690=TAS, GO:0003700=IEA, GO:0006366=TAS, GO:0007275=TAS, GO:0005634=IEA, GO:0048511=IEA, GO:0003677=TAS} multicellular organismal development, rhythmic process, transcription from RNA polymerase II promoter nucleus DNA binding, double-stranded DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human HLTF HPA UniProtKB {GO:0005515=PMID:10391891, GO:0006355=PMID:7876228, GO:0016567=GO_REF:0000041, GO:0006357=GO_REF:0000019, GO:0016874=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0004386=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0016887=GO_REF:0000019, GO:0016568=GO_REF:0000037} Q14527 Helicase-like transcription factor protein 20100326 {GO:0005515=IPI, GO:0006355=TAS, GO:0016567=IEA, GO:0006357=IEA, GO:0016874=IEA, GO:0005730=IDA, GO:0004386=IEA, GO:0005634=IDA, GO:0003677=IEA, GO:0005524=IEA, GO:0006351=IEA, GO:0008270=IEA, GO:0016887=IEA, GO:0016568=IEA} chromatin modification, protein ubiquitination, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus, nucleus ATP binding, ATPase activity, DNA binding, helicase activity, ligase activity, protein binding, zinc ion binding NOT Human HLX MGI UniProtKB {GO:0000976=GO_REF:0000002, GO:0008284=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0046622=GO_REF:0000019, GO:0007275=PMID:8094082, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0048484=GO_REF:0000019, GO:0043565=PMID:9073066, GO:0001889=GO_REF:0000019, GO:0048557=GO_REF:0000019, GO:0007519=GO_REF:0000019, GO:0045629=GO_REF:0000019, GO:0045627=GO_REF:0000019} Q14774 H2.0-like homeobox protein protein 20080331 {GO:0000976=IEA, GO:0008284=IEA, GO:0003700=IEA, GO:0046622=IEA, GO:0007275=TAS, GO:0005634=IEA, GO:0006351=IEA, GO:0030154=IEA, GO:0048484=IEA, GO:0043565=IDA, GO:0001889=IEA, GO:0048557=IEA, GO:0007519=IEA, GO:0045629=IEA, GO:0045627=IEA} cell differentiation, embryonic digestive tract morphogenesis, enteric nervous system development, liver development, multicellular organismal development, negative regulation of T-helper 2 cell differentiation, positive regulation of T-helper 1 cell differentiation, positive regulation of cell proliferation, positive regulation of organ growth, skeletal muscle tissue development, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding Human HM13 UniProtKB UniProtKB {GO:0005515=PMID:19720873, GO:0005791=PMID:15998642, GO:0005886=GO_REF:0000039, GO:0009986=GO_REF:0000024, GO:0005783=GO_REF:0000024, GO:0031293=PMID:16829952, GO:0071458=PMID:15385547, GO:0042803=PMID:15998642, GO:0042500=PMID:16873890, GO:0033619=PMID:14741365, GO:0071556=PMID:15385547, GO:0008233=PMID:14741365, GO:0006509=PMID:17965014} Q8TCT9 Minor histocompatibility antigen H13 protein 20120302 {GO:0005515=IPI, GO:0005791=IDA, GO:0005886=IEA, GO:0009986=ISS, GO:0005783=ISS, GO:0031293=IMP, GO:0071458=IDA, GO:0042803=IDA, GO:0042500=IMP, GO:0033619=IDA, GO:0071556=IDA, GO:0008233=IDA, GO:0006509=IMP} membrane protein ectodomain proteolysis, membrane protein intracellular domain proteolysis, membrane protein proteolysis cell surface, endoplasmic reticulum, integral to cytosolic side of endoplasmic reticulum membrane, integral to lumenal side of endoplasmic reticulum membrane, plasma membrane, rough endoplasmic reticulum aspartic endopeptidase activity, intramembrane cleaving, peptidase activity, protein binding, protein homodimerization activity Human HMBOX1 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0005737=PMID:19757162, GO:0003700=GO_REF:0000002, GO:0005634=PMID:19757162, GO:0045893=GO_REF:0000002, GO:0045892=PMID:19757162, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q6NT76 Homeobox-containing protein 1 protein 20100309 {GO:0043565=IEA, GO:0005737=IDA, GO:0003700=IEA, GO:0005634=IDA, GO:0045893=IEA, GO:0045892=IDA, GO:0003677=IEA, GO:0006351=IEA} negative regulation of transcription, DNA-dependent, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human HMBS Reactome UniProtKB {GO:0018160=GO_REF:0000002, GO:0006778=Reactome:REACT_9431, GO:0044281=Reactome:REACT_111217, GO:0006782=GO_REF:0000041, GO:0033014=GO_REF:0000002, GO:0004418=Reactome:REACT_9446, GO:0005829=Reactome:REACT_9446, GO:0006783=Reactome:REACT_9465} P08397 Porphobilinogen deaminase protein 20130129 {GO:0018160=IEA, GO:0006778=TAS, GO:0044281=TAS, GO:0006782=IEA, GO:0033014=IEA, GO:0004418=TAS, GO:0005829=TAS, GO:0006783=TAS} heme biosynthetic process, peptidyl-pyrromethane cofactor linkage, porphyrin-containing compound metabolic process, protoporphyrinogen IX biosynthetic process, small molecule metabolic process, tetrapyrrole biosynthetic process cytosol hydroxymethylbilane synthase activity Human HMCN1 UniProtKB UniProtKB {GO:0030054=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0005938=GO_REF:0000019, GO:0007601=GO_REF:0000037, GO:0050896=GO_REF:0000037, GO:0005604=GO_REF:0000039} Q96RW7 Hemicentin-1 protein 20130413 {GO:0030054=IEA, GO:0005509=IEA, GO:0005938=IEA, GO:0007601=IEA, GO:0050896=IEA, GO:0005604=IEA} response to stimulus, visual perception basement membrane, cell cortex, cell junction calcium ion binding Human UniProtKB-SubCell:SL-0025 HMG20A HPA UniProtKB {GO:0005515=PMID:23275563, GO:0006355=PMID:10773667, GO:0003700=PMID:10773667, GO:0046982=GO_REF:0000019, GO:0045665=GO_REF:0000019, GO:0006325=PMID:10773667, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000122=GO_REF:0000019, GO:0003677=PMID:10773667, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000019} Q9NP66 High mobility group protein 20A protein 20080818 {GO:0005515=IPI, GO:0006355=NAS, GO:0003700=NAS, GO:0046982=IEA, GO:0045665=IEA, GO:0006325=NAS, GO:0005730=IDA, GO:0005634=IDA, GO:0000122=IEA, GO:0003677=NAS, GO:0006351=IEA, GO:0016568=IEA} chromatin modification, chromatin organization, negative regulation of neuron differentiation, negative regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus, nucleus DNA binding, protein binding, protein heterodimerization activity, sequence-specific DNA binding transcription factor activity NOT Human HMG20B IntAct UniProtKB {GO:0005515=PMID:21399666, GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000029, GO:0046982=GO_REF:0000019, GO:0005694=GO_REF:0000039, GO:0006325=GO_REF:0000029, GO:0005634=GO_REF:0000029, GO:0003677=GO_REF:0000029, GO:0006351=GO_REF:0000037, GO:0007049=GO_REF:0000037, GO:0007596=Reactome:REACT_604, GO:0045666=GO_REF:0000019, GO:0005654=Reactome:REACT_25101, GO:0033234=GO_REF:0000019, GO:0016568=GO_REF:0000037} Q9P0W2 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related protein 20130415 {GO:0005515=IPI, GO:0006355=NAS, GO:0003700=NAS, GO:0046982=IEA, GO:0005694=IEA, GO:0006325=NAS, GO:0005634=NAS, GO:0003677=NAS, GO:0006351=IEA, GO:0007049=IEA, GO:0007596=TAS, GO:0045666=IEA, GO:0005654=TAS, GO:0033234=IEA, GO:0016568=IEA} blood coagulation, cell cycle, chromatin modification, chromatin organization, negative regulation of protein sumoylation, positive regulation of neuron differentiation, regulation of transcription, DNA-dependent, transcription, DNA-dependent chromosome, nucleoplasm, nucleus DNA binding, protein binding, protein heterodimerization activity, sequence-specific DNA binding transcription factor activity Human UniProtKB:P51587 HMGA1 Reactome UniProtKB {GO:0005515=PMID:10428834, GO:0022415=Reactome:REACT_6266, GO:0008285=PMID:16901784, GO:0003700=PMID:10428834, GO:0005634=PMID:16901784, GO:0090402=PMID:16901784, GO:0035985=PMID:16901784, GO:0035986=PMID:16901784, GO:0042974=PMID:10428834, GO:0042975=PMID:10428834, GO:0005829=Reactome:REACT_9450, GO:0046965=PMID:10428834, GO:0030374=PMID:10428834, GO:0016032=Reactome:REACT_6256, GO:2000774=PMID:16901784, GO:0000785=GO_REF:0000002, GO:0031936=PMID:10428834, GO:0005667=PMID:10428834, GO:0006355=PMID:10871404, GO:0006337=PMID:10428834, GO:0009615=PMID:17005673, GO:0003677=PMID:10871404, GO:0006351=GO_REF:0000037, GO:0006461=PMID:10428834, GO:0003680=PMID:10428834, GO:0006268=PMID:10428834, GO:0005654=Reactome:REACT_9054, GO:0019899=PMID:16157300, GO:0045893=PMID:10428834, GO:0045892=PMID:16901784, GO:0075713=Reactome:REACT_8990, GO:0008134=PMID:10428834} P17096 High mobility group protein HMG-I/HMG-Y protein 20130129 {GO:0005515=IPI, GO:0022415=TAS, GO:0008285=IMP, GO:0003700=IMP, GO:0005634=IDA, GO:0090402=IDA, GO:0035985=IDA, GO:0035986=IDA, GO:0042974=IDA, GO:0042975=IDA, GO:0005829=TAS, GO:0046965=IDA, GO:0030374=IMP, GO:0016032=TAS, GO:2000774=IMP, GO:0000785=IEA, GO:0031936=TAS, GO:0005667=TAS, GO:0006355=TAS, GO:0006337=TAS, GO:0009615=IEP, GO:0003677=TAS, GO:0006351=IEA, GO:0006461=TAS, GO:0003680=TAS, GO:0006268=NAS, GO:0005654=TAS, GO:0019899=IPI, GO:0045893=IMP, GO:0045892=IMP, GO:0075713=TAS, GO:0008134=IDA} DNA unwinding involved in replication, establishment of integrated proviral latency, negative regulation of cell proliferation, negative regulation of chromatin silencing, negative regulation of transcription, DNA-dependent, nucleosome disassembly, oncogene-induced senescence, positive regulation of cellular senescence, positive regulation of transcription, DNA-dependent, protein complex assembly, regulation of transcription, DNA-dependent, response to virus, senescence-associated heterochromatin focus assembly, transcription, DNA-dependent, viral reproduction, viral reproductive process chromatin, cytosol, nucleoplasm, nucleus, senescence-associated heterochromatin focus, transcription factor complex AT DNA binding, DNA binding, enzyme binding, ligand-dependent nuclear receptor transcription coactivator activity, peroxisome proliferator activated receptor binding, protein binding, retinoic acid receptor binding, retinoid X receptor binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human HMGA2 InterPro UniProtKB {GO:0005515=PMID:16293633, GO:0003906=PMID:19465398, GO:0000988=PMID:18832382, GO:0030261=GO_REF:0000037, GO:0004677=PMID:19549901, GO:2001022=PMID:19465398, GO:0006325=PMID:19551524, GO:0046332=PMID:18832382, GO:0035985=PMID:16901784, GO:0010564=PMID:14645522, GO:0007283=GO_REF:0000019, GO:0035986=PMID:16901784, GO:0035987=PMID:17624332, GO:0035988=PMID:21484705, GO:0071158=PMID:16061642, GO:0032993=PMID:19465398, GO:0002062=PMID:21484705, GO:0045444=PMID:17624332, GO:0000785=GO_REF:0000002, GO:0000975=PMID:17426251, GO:0008301=PMID:14627817, GO:0071141=PMID:18832382, GO:0031492=PMID:17078040, GO:0007275=PMID:7606786, GO:0001047=PMID:14627817, GO:0000122=PMID:14627817, GO:2000036=PMID:17624332, GO:0043922=PMID:17005673, GO:0043392=PMID:14645522, GO:0003131=PMID:17624332, GO:0006284=PMID:19465398, GO:0070742=PMID:14645522, GO:0045893=PMID:17624332, GO:0045892=PMID:18832382, GO:0008134=PMID:14645522, GO:0051301=GO_REF:0000037, GO:0060123=GO_REF:0000019, GO:0007095=PMID:16061642, GO:0021846=GO_REF:0000019, GO:2000679=PMID:18832382, GO:0031507=PMID:16901784, GO:0030325=GO_REF:0000019, GO:0035497=PMID:14645522, GO:0021983=GO_REF:0000019, GO:0005634=GO_REF:0000002, GO:0090402=PMID:16901784, GO:0001837=PMID:18832382, GO:0031052=PMID:19549901, GO:0042769=PMID:19465398, GO:0045944=PMID:14645522, GO:2001038=PMID:16061642, GO:2000774=PMID:16901784, GO:0048333=PMID:17624332, GO:0040018=GO_REF:0000019, GO:0035019=GO_REF:0000019, GO:2001033=PMID:19549901, GO:0006355=GO_REF:0000002, GO:0043066=PMID:19465398, GO:0043065=PMID:16061642, GO:0048762=PMID:17624332, GO:0045869=PMID:17005673, GO:0035978=PMID:16061642, GO:0035501=PMID:18832382, GO:2000685=PMID:16061642, GO:2000648=PMID:17624332, GO:0035500=PMID:18832382, GO:0000228=GO_REF:0000024, GO:0009615=PMID:17005673, GO:0003677=GO_REF:0000002, GO:0010628=PMID:18832382, GO:0048863=PMID:17078040, GO:0048712=GO_REF:0000019, GO:0051575=PMID:19465398, GO:0001078=PMID:14627817, GO:0001077=PMID:18832382, GO:0007067=GO_REF:0000037, GO:0003680=PMID:18832382, GO:0001071=PMID:17426251, GO:0060613=GO_REF:0000019, GO:0008584=GO_REF:0000019} Q1M188 HMGA2c protein 20130413 {GO:0005515=IPI, GO:0003906=IDA, GO:0000988=IDA, GO:0030261=IEA, GO:0004677=IDA, GO:2001022=IDA, GO:0006325=TAS, GO:0046332=IPI, GO:0035985=IDA, GO:0010564=IDA, GO:0007283=IEA, GO:0035986=IDA, GO:0035987=IMP, GO:0035988=IDA, GO:0071158=IDA, GO:0032993=IDA, GO:0002062=IDA, GO:0045444=IMP, GO:0000785=IEA, GO:0000975=IDA, GO:0008301=IMP, GO:0071141=IDA, GO:0031492=IDA, GO:0007275=TAS, GO:0001047=IDA, GO:0000122=IDA, GO:2000036=IMP, GO:0043922=IDA, GO:0043392=IDA, GO:0003131=IMP, GO:0006284=IDA, GO:0070742=IMP, GO:0045893=IMP, GO:0045892=IDA, GO:0008134=IPI, GO:0051301=IEA, GO:0060123=IEA, GO:0007095=IDA, GO:0021846=IEA, GO:2000679=IDA, GO:0031507=IDA, GO:0030325=IEA, GO:0035497=IDA, GO:0021983=IEA, GO:0005634=IEA, GO:0090402=IDA, GO:0001837=IMP, GO:0031052=IDA, GO:0042769=IDA, GO:0045944=IDA, GO:2001038=IDA, GO:2000774=IMP, GO:0048333=IMP, GO:0040018=IEA, GO:0035019=IEA, GO:2001033=IDA, GO:0006355=IEA, GO:0043066=IDA, GO:0043065=IDA, GO:0048762=IMP, GO:0045869=IDA, GO:0035978=IDA, GO:0035501=IDA, GO:2000685=IDA, GO:2000648=IMP, GO:0035500=IDA, GO:0000228=ISS, GO:0009615=IEP, GO:0003677=IEA, GO:0010628=IDA, GO:0048863=IEP, GO:0048712=IEA, GO:0051575=IDA, GO:0001078=IDA, GO:0001077=IDA, GO:0007067=IEA, GO:0003680=IMP, GO:0001071=IDA, GO:0060613=IEA, GO:0008584=IEA} DNA damage response, detection of DNA damage, adrenal gland development, base-excision repair, cell division, cell proliferation in forebrain, chondrocyte differentiation, chondrocyte proliferation, chromatin organization, chromosome breakage, chromosome condensation, endodermal cell differentiation, epithelial to mesenchymal transition, fat cell differentiation, fat pad development, heterochromatin assembly, histone H2A-S139 phosphorylation, male gonad development, mesenchymal cell differentiation, mesodermal cell differentiation, mesodermal-endodermal cell signaling, mitosis, mitotic G2 DNA damage checkpoint, multicellular organismal development, negative regulation by host of viral transcription, negative regulation of DNA binding, negative regulation of apoptotic process, negative regulation of astrocyte differentiation, negative regulation of double-strand break repair via nonhomologous end joining, negative regulation of retroviral genome replication, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, oncogene-induced senescence, pituitary gland development, positive regulation of apoptotic process, positive regulation of cell cycle arrest, positive regulation of cellular response to X-ray, positive regulation of cellular senescence, positive regulation of gene expression, positive regulation of multicellular organism growth, positive regulation of response to DNA damage stimulus, positive regulation of stem cell proliferation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription regulatory region DNA binding, positive regulation of transcription, DNA-dependent, regulation of cell cycle process, regulation of cellular response to drug, regulation of growth hormone secretion, regulation of stem cell maintenance, regulation of transcription, DNA-dependent, response to virus, senescence-associated heterochromatin focus assembly, somatic stem cell maintenance, spermatogenesis, stem cell differentiation SMAD protein complex, chromatin, nuclear chromosome, nucleus, protein-DNA complex, senescence-associated heterochromatin focus 5'-deoxyribose-5-phosphate lyase activity, AT DNA binding, C2H2 zinc finger domain binding, DNA binding, DNA binding, bending, DNA-(apurinic or apyrimidinic site) lyase activity, DNA-dependent protein kinase activity, MH1 domain binding, MH2 domain binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, SMAD binding, cAMP response element binding, core promoter binding, nucleic acid binding transcription factor activity, nucleosomal DNA binding, protein binding, protein binding transcription factor activity, regulatory region DNA binding, transcription factor binding Human InterPro:IPR000116|InterPro:IPR000637 HMGB1 InterPro UniProtKB {GO:0005515=PMID:19505873, GO:0000793=PMID:12925773, GO:0003700=PMID:19223331, GO:0001654=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0031175=GO_REF:0000024, GO:0003690=GO_REF:0000024, GO:0050786=GO_REF:0000024, GO:0003697=GO_REF:0000024, GO:0017053=PMID:19158276, GO:0017055=PMID:8006019, GO:0033151=PMID:9166431, GO:2000426=GO_REF:0000019, GO:0008301=PMID:19223331, GO:0051384=GO_REF:0000019, GO:0000122=PMID:19158276, GO:0005125=GO_REF:0000019, GO:0042056=GO_REF:0000024, GO:0043280=PMID:19800306, GO:0051103=GO_REF:0000024, GO:0045087=Reactome:REACT_6802, GO:0043388=PMID:19223331, GO:0006288=PMID:9600082, GO:0005654=Reactome:REACT_13513, GO:0008134=PMID:19223331, GO:0002437=PMID:19841752, GO:0043005=GO_REF:0000019, GO:0010858=GO_REF:0000019, GO:0030324=GO_REF:0000019, GO:0005634=GO_REF:0000002, GO:0006921=Reactome:REACT_995, GO:0005737=GO_REF:0000019, GO:0045639=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0070491=PMID:19223331, GO:0001773=GO_REF:0000024, GO:0043065=PMID:19800306, GO:0006357=PMID:11748232, GO:0002407=GO_REF:0000024, GO:0006915=Reactome:REACT_578, GO:0006310=GO_REF:0000024, GO:0005576=Reactome:REACT_25382, GO:0030295=GO_REF:0000019, GO:0003677=GO_REF:0000002, GO:0050918=GO_REF:0000024, GO:0003684=GO_REF:0000024, GO:0045819=GO_REF:0000019, GO:0006309=Reactome:REACT_1213, GO:0006265=GO_REF:0000024} Q5T7C6 High mobility group protein B1 protein 20130413 {GO:0005515=IPI, GO:0000793=IDA, GO:0003700=IDA, GO:0001654=IEA, GO:0005615=IEA, GO:0031175=ISS, GO:0003690=ISS, GO:0050786=ISS, GO:0003697=ISS, GO:0017053=IDA, GO:0017055=IDA, GO:0033151=IDA, GO:2000426=IEA, GO:0008301=IMP, GO:0051384=IEA, GO:0000122=IMP, GO:0005125=IEA, GO:0042056=ISS, GO:0043280=IDA, GO:0051103=ISS, GO:0045087=TAS, GO:0043388=IDA, GO:0006288=IDA, GO:0005654=TAS, GO:0008134=IPI, GO:0002437=IEP, GO:0043005=IEA, GO:0010858=IEA, GO:0030324=IEA, GO:0005634=IEA, GO:0006921=TAS, GO:0005737=IEA, GO:0045639=IEA, GO:0045944=IEA, GO:0070491=IPI, GO:0001773=ISS, GO:0043065=IDA, GO:0006357=IDA, GO:0002407=ISS, GO:0006915=TAS, GO:0006310=ISS, GO:0005576=TAS, GO:0030295=IEA, GO:0003677=IEA, GO:0050918=ISS, GO:0003684=ISS, GO:0045819=IEA, GO:0006309=TAS, GO:0006265=ISS} DNA ligation involved in DNA repair, DNA recombination, DNA topological change, V(D)J recombination, apoptotic DNA fragmentation, apoptotic process, base-excision repair, DNA ligation, cellular component disassembly involved in execution phase of apoptosis, dendritic cell chemotaxis, eye development, inflammatory response to antigenic stimulus, innate immune response, lung development, myeloid dendritic cell activation, negative regulation of RNA polymerase II transcriptional preinitiation complex assembly, negative regulation of apoptotic cell clearance, negative regulation of transcription from RNA polymerase II promoter, neuron projection development, positive chemotaxis, positive regulation of DNA binding, positive regulation of apoptotic process, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of glycogen catabolic process, positive regulation of myeloid cell differentiation, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, response to glucocorticoid stimulus condensed chromosome, cytoplasm, extracellular region, extracellular space, neuron projection, nucleoplasm, nucleus, transcriptional repressor complex DNA binding, DNA binding, bending, RAGE receptor binding, calcium-dependent protein kinase regulator activity, chemoattractant activity, cytokine activity, damaged DNA binding, double-stranded DNA binding, protein binding, protein kinase activator activity, repressing transcription factor binding, sequence-specific DNA binding transcription factor activity, single-stranded DNA binding, transcription factor binding Human InterPro:IPR017967 HMGB2 GOC UniProtKB {GO:0005515=PMID:9636147, GO:0000793=PMID:12925773, GO:0048471=PMID:11909973, GO:0003700=PMID:19223331, GO:0044212=PMID:19965638, GO:0007289=GO_REF:0000019, GO:0006325=PMID:15504738, GO:0005634=PMID:8339930, GO:0005615=PMID:19811285, GO:0006921=Reactome:REACT_995, GO:0032075=PMID:978439, GO:0045654=PMID:19965638, GO:0005737=PMID:11909973, GO:0003690=GO_REF:0000024, GO:0050786=PMID:19811285, GO:0003697=GO_REF:0000024, GO:0045944=PMID:19223331, GO:0033151=GO_REF:0000024, GO:0006357=PMID:7797075, GO:0008301=PMID:11909973, GO:0048015=PMID:15504738, GO:0019904=GO_REF:0000019, GO:0006334=PMID:11909973, GO:0006915=Reactome:REACT_578, GO:0048545=GO_REF:0000019, GO:0042056=PMID:19811285, GO:0003677=PMID:11909973, GO:0050918=PMID:19811285, GO:0003684=PMID:8226934, GO:0043234=PMID:11909973, GO:0071222=PMID:19811285, GO:0051103=GO_REF:0000024, GO:0001938=PMID:19811285, GO:0006309=Reactome:REACT_1213, GO:0060326=PMID:19811285, GO:0045648=PMID:19965638, GO:0043388=PMID:19965638, GO:0005654=Reactome:REACT_13513, GO:0006288=PMID:9600082, GO:0045893=PMID:19965638, GO:0045892=PMID:9636147, GO:0006265=GO_REF:0000024, GO:0008584=GO_REF:0000019} P26583 High mobility group protein B2 protein 20130413 {GO:0005515=IPI, GO:0000793=IDA, GO:0048471=IDA, GO:0003700=IDA, GO:0044212=IDA, GO:0007289=IEA, GO:0006325=NAS, GO:0005634=IDA, GO:0005615=IDA, GO:0006921=TAS, GO:0032075=IDA, GO:0045654=IMP, GO:0005737=IDA, GO:0003690=ISS, GO:0050786=IGI, GO:0003697=ISS, GO:0045944=IDA, GO:0033151=ISS, GO:0006357=IDA, GO:0008301=IDA, GO:0048015=NAS, GO:0019904=IEA, GO:0006334=NAS, GO:0006915=TAS, GO:0048545=IEA, GO:0042056=IDA, GO:0003677=IMP, GO:0050918=IDA, GO:0003684=IDA, GO:0043234=IDA, GO:0071222=IEP, GO:0051103=ISS, GO:0001938=IDA, GO:0006309=TAS, GO:0060326=IDA, GO:0045648=IMP, GO:0043388=IDA, GO:0005654=TAS, GO:0006288=IDA, GO:0045893=IDA, GO:0045892=IDA, GO:0006265=ISS, GO:0008584=IEA} DNA ligation involved in DNA repair, DNA topological change, V(D)J recombination, apoptotic DNA fragmentation, apoptotic process, base-excision repair, DNA ligation, cell chemotaxis, cellular component disassembly involved in execution phase of apoptosis, cellular response to lipopolysaccharide, chromatin organization, male gonad development, negative regulation of transcription, DNA-dependent, nucleosome assembly, phosphatidylinositol-mediated signaling, positive chemotaxis, positive regulation of DNA binding, positive regulation of endothelial cell proliferation, positive regulation of erythrocyte differentiation, positive regulation of megakaryocyte differentiation, positive regulation of nuclease activity, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, response to steroid hormone stimulus, spermatid nucleus differentiation condensed chromosome, cytoplasm, extracellular space, nucleoplasm, nucleus, perinuclear region of cytoplasm, protein complex DNA binding, DNA binding, bending, RAGE receptor binding, chemoattractant activity, damaged DNA binding, double-stranded DNA binding, protein binding, protein domain specific binding, sequence-specific DNA binding transcription factor activity, single-stranded DNA binding, transcription regulatory region DNA binding Human HMGB3 PINC UniProtKB {GO:0003690=GO_REF:0000024, GO:0008301=GO_REF:0000024, GO:0005694=GO_REF:0000039, GO:0007275=PMID:9598312, GO:0006310=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000002} O15347 High mobility group protein B3 protein 20030904 {GO:0003690=ISS, GO:0008301=ISS, GO:0005694=IEA, GO:0007275=TAS, GO:0006310=ISS, GO:0005634=IEA, GO:0003677=IEA} DNA recombination, multicellular organismal development chromosome, nucleus DNA binding, DNA binding, bending, double-stranded DNA binding Human HMGB4 UniProtKB UniProtKB {GO:0005694=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037} Q8WW32 High mobility group protein B4 protein 20130413 {GO:0005694=IEA, GO:0005634=IEA, GO:0003677=IEA} chromosome, nucleus DNA binding Human UniProtKB-SubCell:SL-0468 HMGCL Reactome UniProtKB {GO:0031406=GO_REF:0000019, GO:0005743=GO_REF:0000019, GO:0009790=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0046872=PMID:16330550, GO:0042803=PMID:12464283, GO:0005739=PMID:9869651, GO:0042594=GO_REF:0000019, GO:0005759=Reactome:REACT_2103, GO:0000062=GO_REF:0000019, GO:0006552=PMID:9200711, GO:0044255=Reactome:REACT_22279, GO:0005777=PMID:9869651, GO:0006637=GO_REF:0000019, GO:0000287=PMID:9200711, GO:0030145=PMID:9200711, GO:0051262=PMID:12464283, GO:0007584=GO_REF:0000019, GO:0005102=PMID:20178365, GO:0001889=GO_REF:0000019, GO:0070542=GO_REF:0000019, GO:0046951=Reactome:REACT_1464, GO:0046950=Reactome:REACT_1861, GO:0007005=GO_REF:0000019, GO:0004419=Reactome:REACT_2103} P35914 Hydroxymethylglutaryl-CoA lyase, mitochondrial protein 20100319 {GO:0031406=IEA, GO:0005743=IEA, GO:0009790=IEA, GO:0044281=TAS, GO:0046872=IDA, GO:0042803=IDA, GO:0005739=IDA, GO:0042594=IEA, GO:0005759=TAS, GO:0000062=IEA, GO:0006552=NAS, GO:0044255=TAS, GO:0005777=IDA, GO:0006637=IEA, GO:0000287=IDA, GO:0030145=IDA, GO:0051262=IDA, GO:0007584=IEA, GO:0005102=IPI, GO:0001889=IEA, GO:0070542=IEA, GO:0046951=TAS, GO:0046950=TAS, GO:0007005=IEA, GO:0004419=TAS} acyl-CoA metabolic process, cellular ketone body metabolic process, cellular lipid metabolic process, embryo development, ketone body biosynthetic process, leucine catabolic process, liver development, mitochondrion organization, protein tetramerization, response to fatty acid, response to nutrient, response to starvation, small molecule metabolic process mitochondrial inner membrane, mitochondrial matrix, mitochondrion, peroxisome carboxylic acid binding, fatty-acyl-CoA binding, hydroxymethylglutaryl-CoA lyase activity, magnesium ion binding, manganese ion binding, metal ion binding, protein homodimerization activity, receptor binding Human HMGCR Reactome UniProtKB {GO:0050662=GO_REF:0000002, GO:0006695=Reactome:REACT_9405, GO:0005783=PMID:17180682, GO:0045471=GO_REF:0000019, GO:0032874=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0009790=GO_REF:0000019, GO:0015936=GO_REF:0000002, GO:0070402=PMID:10698924, GO:0042803=GO_REF:0000019, GO:0043231=GO_REF:0000019, GO:0061045=GO_REF:0000019, GO:0043407=GO_REF:0000019, GO:0045908=GO_REF:0000019, GO:0010666=GO_REF:0000019, GO:0045445=GO_REF:0000019, GO:0070374=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0005778=PMID:17180682, GO:0010664=GO_REF:0000019, GO:0051262=PMID:10698924, GO:0007584=GO_REF:0000019, GO:0004420=GO_REF:0000003, GO:0007568=GO_REF:0000019, GO:0008299=GO_REF:0000019, GO:0048643=GO_REF:0000019, GO:0048661=GO_REF:0000019, GO:0006743=GO_REF:0000019, GO:0008542=GO_REF:0000019, GO:0005789=Reactome:REACT_115997, GO:0016021=GO_REF:0000037, GO:0061179=GO_REF:0000019, GO:0042282=PMID:2991281} P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase protein 20130301 {GO:0050662=IEA, GO:0006695=TAS, GO:0005783=IDA, GO:0045471=IEA, GO:0032874=IEA, GO:0044281=TAS, GO:0009790=IEA, GO:0015936=IEA, GO:0070402=IDA, GO:0042803=IEA, GO:0043231=IEA, GO:0061045=IEA, GO:0043407=IEA, GO:0045908=IEA, GO:0010666=IEA, GO:0045445=IEA, GO:0070374=IEA, GO:0044255=TAS, GO:0005778=IDA, GO:0010664=IEA, GO:0051262=IDA, GO:0007584=IEA, GO:0004420=IEA, GO:0007568=IEA, GO:0008299=IEA, GO:0048643=IEA, GO:0048661=IEA, GO:0006743=IEA, GO:0008542=IEA, GO:0005789=TAS, GO:0016021=IEA, GO:0061179=IEA, GO:0042282=IDA} aging, cellular lipid metabolic process, cholesterol biosynthetic process, coenzyme A metabolic process, embryo development, isoprenoid biosynthetic process, myoblast differentiation, negative regulation of MAP kinase activity, negative regulation of insulin secretion involved in cellular response to glucose stimulus, negative regulation of striated muscle cell apoptotic process, negative regulation of vasodilation, negative regulation of wound healing, positive regulation of ERK1 and ERK2 cascade, positive regulation of cardiac muscle cell apoptotic process, positive regulation of skeletal muscle tissue development, positive regulation of smooth muscle cell proliferation, positive regulation of stress-activated MAPK cascade, protein tetramerization, response to ethanol, response to nutrient, small molecule metabolic process, ubiquinone metabolic process, visual learning endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle, peroxisomal membrane NADPH binding, coenzyme binding, hydroxymethylglutaryl-CoA reductase (NADPH) activity, hydroxymethylglutaryl-CoA reductase activity, protein homodimerization activity Human HMGCS1 HPA UniProtKB {GO:0006629=PMID:7913309, GO:0006695=Reactome:REACT_9405, GO:0005886=GO_REF:0000052, GO:0009645=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0014074=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0005829=Reactome:REACT_115739, GO:0071372=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0071397=GO_REF:0000019, GO:0008144=GO_REF:0000019, GO:0001101=GO_REF:0000019, GO:0033197=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0004421=GO_REF:0000003, GO:0043177=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0046690=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0008299=GO_REF:0000002, GO:0001889=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0055094=GO_REF:0000019, GO:0016853=GO_REF:0000019, GO:0008584=GO_REF:0000019} Q01581 Hydroxymethylglutaryl-CoA synthase, cytoplasmic protein 20110516 {GO:0006629=NAS, GO:0006695=TAS, GO:0005886=IDA, GO:0009645=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0014074=IEA, GO:0042803=IEA, GO:0005829=TAS, GO:0071372=IEA, GO:0005737=IDA, GO:0071397=IEA, GO:0008144=IEA, GO:0001101=IEA, GO:0033197=IEA, GO:0044255=TAS, GO:0004421=IEA, GO:0043177=IEA, GO:0042493=IEA, GO:0046690=IEA, GO:0005730=IDA, GO:0008299=IEA, GO:0001889=IEA, GO:0007420=IEA, GO:0055094=IEA, GO:0016853=IEA, GO:0008584=IEA} brain development, cellular lipid metabolic process, cellular response to cholesterol, cellular response to follicle-stimulating hormone stimulus, cholesterol biosynthetic process, isoprenoid biosynthetic process, lipid metabolic process, liver development, male gonad development, response to acid, response to drug, response to lipoprotein particle stimulus, response to low light intensity stimulus, response to purine-containing compound, response to tellurium ion, response to vitamin E, small molecule metabolic process cytoplasm, cytosol, nucleolus, nucleus, plasma membrane drug binding, hydroxymethylglutaryl-CoA synthase activity, isomerase activity, organic acid binding, protein homodimerization activity Human HMGCS2 Reactome UniProtKB {GO:0005739=PMID:7851882, GO:0006695=GO_REF:0000037, GO:0004421=GO_REF:0000003, GO:0046951=Reactome:REACT_1464, GO:0005759=Reactome:REACT_116136, GO:0046950=Reactome:REACT_1861, GO:0005743=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0008299=GO_REF:0000002, GO:0044255=Reactome:REACT_22279} P54868 Hydroxymethylglutaryl-CoA synthase, mitochondrial protein 20130301 {GO:0005739=TAS, GO:0006695=IEA, GO:0004421=IEA, GO:0046951=TAS, GO:0005759=TAS, GO:0046950=TAS, GO:0005743=IEA, GO:0044281=TAS, GO:0008299=IEA, GO:0044255=TAS} cellular ketone body metabolic process, cellular lipid metabolic process, cholesterol biosynthetic process, isoprenoid biosynthetic process, ketone body biosynthetic process, small molecule metabolic process mitochondrial inner membrane, mitochondrial matrix, mitochondrion hydroxymethylglutaryl-CoA synthase activity Human HMGN1 PINC UniProtKB {GO:0050678=GO_REF:0000019, GO:0031492=GO_REF:0000002, GO:0006325=GO_REF:0000019, GO:0005634=PMID:16780588, GO:0003677=PMID:8047885, GO:0048597=GO_REF:0000019, GO:0000720=GO_REF:0000019, GO:0010225=GO_REF:0000019, GO:0040034=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0032786=PMID:8047885, GO:0006283=GO_REF:0000019, GO:0010224=GO_REF:0000019, GO:0000785=GO_REF:0000002} P05114 Non-histone chromosomal protein HMG-14 protein 20030904 {GO:0050678=IEA, GO:0031492=IEA, GO:0006325=IEA, GO:0005634=IDA, GO:0003677=TAS, GO:0048597=IEA, GO:0000720=IEA, GO:0010225=IEA, GO:0040034=IEA, GO:0005737=IEA, GO:0032786=TAS, GO:0006283=IEA, GO:0010224=IEA, GO:0000785=IEA} chromatin organization, positive regulation of DNA-dependent transcription, elongation, post-embryonic camera-type eye morphogenesis, pyrimidine dimer repair by nucleotide-excision repair, regulation of development, heterochronic, regulation of epithelial cell proliferation, response to UV-B, response to UV-C, transcription-coupled nucleotide-excision repair chromatin, cytoplasm, nucleus DNA binding, nucleosomal DNA binding Human HMGN2 HPA UniProtKB {GO:0006355=GO_REF:0000029, GO:0005737=GO_REF:0000039, GO:0006325=GO_REF:0000029, GO:0031492=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000029, GO:0000785=GO_REF:0000002} P05204 Non-histone chromosomal protein HMG-17 protein 20120912 {GO:0006355=NAS, GO:0005737=IEA, GO:0006325=NAS, GO:0031492=IEA, GO:0005634=IDA, GO:0003677=NAS, GO:0000785=IEA} chromatin organization, regulation of transcription, DNA-dependent chromatin, cytoplasm, nucleus DNA binding, nucleosomal DNA binding Human HMGN3 HPA UniProtKB {GO:0046966=PMID:7776974, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0051091=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0031492=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0000785=GO_REF:0000002, GO:0061178=GO_REF:0000019, GO:0016568=GO_REF:0000037} Q15651 High mobility group nucleosome-binding domain-containing protein 3 protein 20101115 {GO:0046966=NAS, GO:0008150=ND, GO:0005737=IDA, GO:0051091=IEA, GO:0045944=IEA, GO:0005730=IDA, GO:0031492=IEA, GO:0005634=IDA, GO:0000785=IEA, GO:0061178=IEA, GO:0016568=IEA} biological_process, chromatin modification, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, regulation of insulin secretion involved in cellular response to glucose stimulus chromatin, cytoplasm, nucleolus, nucleus nucleosomal DNA binding, thyroid hormone receptor binding Human HMGN4 HPA UniProtKB {GO:0031492=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0000785=GO_REF:0000002} O00479 High mobility group nucleosome-binding domain-containing protein 4 protein 20120912 {GO:0031492=IEA, GO:0005634=IDA, GO:0000785=IEA} chromatin, nucleus nucleosomal DNA binding Human HMGN5 HPA UniProtKB {GO:0006355=PMID:11161810, GO:0006357=GO_REF:0000019, GO:0003682=PMID:11161810, GO:0005730=GO_REF:0000052, GO:0031492=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0005654=GO_REF:0000019, GO:0045893=PMID:11161810, GO:0000785=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0016568=GO_REF:0000037} Q5JSL0 High mobility group nucleosome-binding domain-containing protein 5 protein 20101115 {GO:0006355=NAS, GO:0006357=IEA, GO:0003682=NAS, GO:0005730=IDA, GO:0031492=IEA, GO:0005634=IDA, GO:0005654=IEA, GO:0045893=NAS, GO:0000785=IEA, GO:0006351=IEA, GO:0043231=IDA, GO:0016568=IEA} chromatin modification, positive regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription, DNA-dependent chromatin, intracellular membrane-bounded organelle, nucleolus, nucleoplasm, nucleus chromatin binding, nucleosomal DNA binding Human HMGXB3 GOC UniProtKB {GO:0016310=PMID:9027509, GO:0008150=GO_REF:0000015, GO:0016301=PMID:9027509, GO:0005634=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0003677=GO_REF:0000037} Q12766 HMG domain-containing protein 3 protein 20130413 {GO:0016310=NAS, GO:0008150=ND, GO:0016301=NAS, GO:0005634=IEA, GO:0005575=ND, GO:0003677=IEA} biological_process, phosphorylation cellular_component, nucleus DNA binding, kinase activity Human HMGXB4 UniProtKB UniProtKB {GO:0008333=PMID:10329004, GO:0030178=GO_REF:0000024, GO:0005634=GO_REF:0000029, GO:0016589=PMID:20850016, GO:0016055=GO_REF:0000037, GO:0003677=GO_REF:0000029} Q9UGU5 HMG domain-containing protein 4 protein 20101105 {GO:0008333=NAS, GO:0030178=ISS, GO:0005634=NAS, GO:0016589=IDA, GO:0016055=IEA, GO:0003677=NAS} Wnt receptor signaling pathway, endosome to lysosome transport, negative regulation of Wnt receptor signaling pathway NURF complex, nucleus DNA binding Human HMHA1 Reactome UniProtKB {GO:0035556=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007264=Reactome:REACT_11044, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} Q92619 Minor histocompatibility protein HA-1 protein 20130301 {GO:0035556=IEA, GO:0005622=IEA, GO:0051056=TAS, GO:0007264=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0005096=IEA} intracellular signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol, intracellular GTPase activator activity, metal ion binding Human HMMR Reactome UniProtKB {GO:0005737=GO_REF:0000039, GO:0005886=Reactome:REACT_120971, GO:0009986=GO_REF:0000039, GO:0005540=GO_REF:0000037, GO:0005975=Reactome:REACT_474, GO:0030212=Reactome:REACT_121083, GO:0044281=Reactome:REACT_111217, GO:0030214=Reactome:REACT_120996, GO:0030203=Reactome:REACT_121315} O75330 Hyaluronan mediated motility receptor protein 20130301 {GO:0005737=IEA, GO:0005886=TAS, GO:0009986=IEA, GO:0005540=IEA, GO:0005975=TAS, GO:0030212=TAS, GO:0044281=TAS, GO:0030214=TAS, GO:0030203=TAS} carbohydrate metabolic process, glycosaminoglycan metabolic process, hyaluronan catabolic process, hyaluronan metabolic process, small molecule metabolic process cell surface, cytoplasm, plasma membrane hyaluronic acid binding Human HMOX1 BHF-UCL UniProtKB {GO:0031670=GO_REF:0000019, GO:0008219=GO_REF:0000024, GO:0042542=GO_REF:0000024, GO:0043627=GO_REF:0000019, GO:0005615=PMID:18307065, GO:0007243=PMID:17652371, GO:0042803=PMID:19556236, GO:0006879=Reactome:REACT_25060, GO:0043524=GO_REF:0000019, GO:0051260=PMID:19556236, GO:0042167=PMID:17915953, GO:0043123=PMID:12761501, GO:0006979=PMID:9884342, GO:0043305=GO_REF:0000019, GO:0032764=GO_REF:0000019, GO:0014806=PMID:18289072, GO:0006788=PMID:17915953, GO:0043392=GO_REF:0000019, GO:0006778=Reactome:REACT_9431, GO:0005789=Reactome:REACT_22100, GO:0019899=PMID:15516695, GO:0045080=PMID:17652371, GO:0020037=PMID:17915953, GO:0005783=GO_REF:0000024, GO:0007264=GO_REF:0000019, GO:0004392=PMID:17915953, GO:0034101=PMID:9884342, GO:0005634=GO_REF:0000024, GO:0004630=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0055072=PMID:17915953, GO:0043433=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=GO_REF:0000019, GO:0051090=GO_REF:0000024, GO:0034383=PMID:9884342, GO:0045909=PMID:17915953, GO:0071276=GO_REF:0000019, GO:0004871=PMID:12761501, GO:0001666=GO_REF:0000019, GO:0007588=PMID:17915953, GO:0043066=PMID:18202225, GO:0008630=GO_REF:0000019, GO:0005730=GO_REF:0000019, GO:0002246=PMID:9884342, GO:0045765=PMID:17652371, GO:0071456=PMID:12511571, GO:0048662=PMID:17600318, GO:0043619=GO_REF:0000024, GO:0001525=PMID:12239590, GO:0048661=PMID:17600318, GO:0055085=Reactome:REACT_15518, GO:0045766=GO_REF:0000019, GO:0016020=PMID:3345742, GO:0002686=PMID:14525760, GO:0005901=GO_REF:0000019, GO:0001935=PMID:12239590, GO:0008217=GO_REF:0000019, GO:0035094=PMID:18205746} P09601 Heme oxygenase 1 protein 20080528 {GO:0031670=IEA, GO:0008219=ISS, GO:0042542=ISS, GO:0043627=IEA, GO:0005615=TAS, GO:0007243=TAS, GO:0042803=IDA, GO:0006879=TAS, GO:0043524=IEA, GO:0051260=IDA, GO:0042167=IDA, GO:0043123=IMP, GO:0006979=IMP, GO:0043305=IEA, GO:0032764=IEA, GO:0014806=TAS, GO:0006788=IDA, GO:0043392=IEA, GO:0006778=TAS, GO:0005789=TAS, GO:0019899=ISS, GO:0045080=TAS, GO:0020037=IDA, GO:0005783=ISS, GO:0007264=IEA, GO:0004392=IDA, GO:0034101=IMP, GO:0005634=ISS, GO:0004630=IEA, GO:0044281=TAS, GO:0055072=IDA, GO:0043433=IEA, GO:0046872=IEA, GO:0005829=IEA, GO:0051090=ISS, GO:0034383=TAS, GO:0045909=IC, GO:0071276=IEA, GO:0004871=IMP, GO:0001666=IEA, GO:0007588=IC, GO:0043066=IMP, GO:0008630=IEA, GO:0005730=IEA, GO:0002246=IMP, GO:0045765=TAS, GO:0071456=IEP, GO:0048662=IDA, GO:0043619=ISS, GO:0001525=TAS, GO:0048661=IDA, GO:0055085=TAS, GO:0045766=IEA, GO:0016020=TAS, GO:0002686=TAS, GO:0005901=IEA, GO:0001935=TAS, GO:0008217=IEA, GO:0035094=IDA} angiogenesis, cell death, cellular iron ion homeostasis, cellular response to cadmium ion, cellular response to hypoxia, cellular response to nutrient, endothelial cell proliferation, erythrocyte homeostasis, excretion, heme catabolic process, heme oxidation, intracellular protein kinase cascade, intrinsic apoptotic signaling pathway in response to DNA damage, iron ion homeostasis, low-density lipoprotein particle clearance, negative regulation of DNA binding, negative regulation of apoptotic process, negative regulation of leukocyte migration, negative regulation of mast cell cytokine production, negative regulation of mast cell degranulation, negative regulation of neuron apoptotic process, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of smooth muscle cell proliferation, porphyrin-containing compound metabolic process, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of angiogenesis, positive regulation of chemokine biosynthetic process, positive regulation of smooth muscle cell proliferation, positive regulation of vasodilation, protein homooligomerization, regulation of angiogenesis, regulation of blood pressure, regulation of sequence-specific DNA binding transcription factor activity, regulation of transcription from RNA polymerase II promoter in response to oxidative stress, response to estrogen stimulus, response to hydrogen peroxide, response to hypoxia, response to nicotine, response to oxidative stress, small GTPase mediated signal transduction, small molecule metabolic process, smooth muscle hyperplasia, transmembrane transport, wound healing involved in inflammatory response caveola, cytosol, endoplasmic reticulum, endoplasmic reticulum membrane, extracellular space, membrane, nucleolus, nucleus enzyme binding, heme binding, heme oxygenase (decyclizing) activity, metal ion binding, phospholipase D activity, protein homodimerization activity, signal transducer activity Human HMOX2 Reactome UniProtKB {GO:0005515=PMID:15528406, GO:0001666=PMID:15528406, GO:0005886=PMID:15528406, GO:0004392=PMID:1575508, GO:0006788=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0055085=Reactome:REACT_15518, GO:0046872=GO_REF:0000037, GO:0006879=Reactome:REACT_25060, GO:0006778=Reactome:REACT_9431, GO:0005789=Reactome:REACT_22100, GO:0042167=Reactome:REACT_22297, GO:0006979=GO_REF:0000019} P30519 Heme oxygenase 2 protein 20130301 {GO:0005515=IPI, GO:0001666=IDA, GO:0005886=IDA, GO:0004392=IDA, GO:0006788=IEA, GO:0044281=TAS, GO:0055085=TAS, GO:0046872=IEA, GO:0006879=TAS, GO:0006778=TAS, GO:0005789=TAS, GO:0042167=TAS, GO:0006979=IEA} cellular iron ion homeostasis, heme catabolic process, heme oxidation, porphyrin-containing compound metabolic process, response to hypoxia, response to oxidative stress, small molecule metabolic process, transmembrane transport endoplasmic reticulum membrane, plasma membrane heme oxygenase (decyclizing) activity, metal ion binding, protein binding Human HMX1 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0005634=PMID:10206974, GO:0007275=GO_REF:0000037, GO:0045892=PMID:10206974, GO:0003677=PMID:10206974, GO:0006351=GO_REF:0000037} Q9NP08 Homeobox protein HMX1 protein 20110607 {GO:0043565=IEA, GO:0003700=IEA, GO:0005634=IC, GO:0007275=IEA, GO:0045892=IMP, GO:0003677=IMP, GO:0006351=IEA} multicellular organismal development, negative regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human GO:0045892 HMX2 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0008284=GO_REF:0000019, GO:0042472=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0007420=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037} A2RU54 Homeobox protein HMX2 protein 20130413 {GO:0043565=IEA, GO:0008284=IEA, GO:0042472=IEA, GO:0003700=IEA, GO:0007420=IEA, GO:0005634=IEA, GO:0030154=IEA, GO:0006351=IEA} brain development, cell differentiation, inner ear morphogenesis, positive regulation of cell proliferation, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0191 HMX3 UniProtKB UniProtKB {GO:0043565=GO_REF:0000019, GO:0042472=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0007566=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0060135=GO_REF:0000019, GO:0050885=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037} A6NHT5 Homeobox protein HMX3 protein 20130413 {GO:0043565=IEA, GO:0042472=IEA, GO:0003700=IEA, GO:0007566=IEA, GO:0007420=IEA, GO:0060135=IEA, GO:0050885=IEA, GO:0005634=IEA, GO:0030154=IEA, GO:0006351=IEA} brain development, cell differentiation, embryo implantation, inner ear morphogenesis, maternal process involved in female pregnancy, neuromuscular process controlling balance, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0191 HN1 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039} Q9UK76 Hematological and neurological expressed 1 protein protein 20130413 {GO:0005634=IEA} nucleus Human UniProtKB-SubCell:SL-0191 HN1L HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005634=GO_REF:0000039} Q9H910 Hematological and neurological expressed 1-like protein protein 20111111 {GO:0005737=IDA, GO:0005886=IDA, GO:0005634=IEA} cytoplasm, nucleus, plasma membrane Human HNF1A BHF-UCL UniProtKB {GO:0005515=PMID:19264593, GO:0003700=PMID:11980910, GO:0030111=GO_REF:0000019, GO:0044212=PMID:15961790, GO:0006699=GO_REF:0000019, GO:0045453=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0048608=GO_REF:0000019, GO:0003690=GO_REF:0000019, GO:0046323=PMID:11269503, GO:0046983=PMID:12453420, GO:0006979=GO_REF:0000019, GO:0035623=PMID:11269503, GO:0046982=GO_REF:0000019, GO:0043691=GO_REF:0000019, GO:0001890=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0006783=GO_REF:0000019, GO:0001889=GO_REF:0000019, GO:0043234=PMID:11980910, GO:0048341=GO_REF:0000019, GO:0015908=GO_REF:0000019, GO:0045120=GO_REF:0000019, GO:0045893=PMID:12453420, GO:0030073=GO_REF:0000019, GO:0035565=PMID:15355349, GO:0008134=GO_REF:0000019, GO:0001750=GO_REF:0000019, GO:0005634=PMID:15355349, GO:0030326=GO_REF:0000019, GO:0060261=PMID:15355349, GO:0060395=GO_REF:0000019, GO:0005737=PMID:15355349, GO:0008104=GO_REF:0000019, GO:0045944=GO_REF:0000024, GO:0006633=GO_REF:0000019, GO:0006338=GO_REF:0000019, GO:0008203=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0006357=PMID:10330009, GO:0001824=GO_REF:0000019, GO:0042593=PMID:11269503, GO:0003677=GO_REF:0000038, GO:0009749=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0001077=GO_REF:0000024, GO:0050796=GO_REF:0000019, GO:0015721=GO_REF:0000019, GO:0031018=GO_REF:0000019} P20823 Hepatocyte nuclear factor 1-alpha protein 20110311 {GO:0005515=IPI, GO:0003700=IDA, GO:0030111=IEA, GO:0044212=IDA, GO:0006699=IEA, GO:0045453=IEA, GO:0042803=IEA, GO:0048608=IEA, GO:0003690=IEA, GO:0046323=IMP, GO:0046983=IPI, GO:0006979=IEA, GO:0035623=IMP, GO:0046982=IEA, GO:0043691=IEA, GO:0001890=IEA, GO:0000122=IEA, GO:0006783=IEA, GO:0001889=IEA, GO:0043234=IDA, GO:0048341=IEA, GO:0015908=IEA, GO:0045120=IEA, GO:0045893=IDA, GO:0030073=IEA, GO:0035565=IMP, GO:0008134=IEA, GO:0001750=IEA, GO:0005634=IDA, GO:0030326=IEA, GO:0060261=IGI, GO:0060395=IEA, GO:0005737=IDA, GO:0008104=IEA, GO:0045944=ISS, GO:0006633=IEA, GO:0006338=IEA, GO:0008203=IEA, GO:0005667=IEA, GO:0006357=IDA, GO:0001824=IEA, GO:0042593=IMP, GO:0003677=IEA, GO:0009749=IEA, GO:0043565=IEA, GO:0001077=ISS, GO:0050796=IEA, GO:0015721=IEA, GO:0031018=IEA} SMAD protein signal transduction, bile acid and bile salt transport, bile acid biosynthetic process, blastocyst development, bone resorption, cholesterol metabolic process, chromatin remodeling, embryonic limb morphogenesis, endocrine pancreas development, fatty acid biosynthetic process, fatty acid transport, glucose homeostasis, glucose import, heme biosynthetic process, insulin secretion, liver development, negative regulation of transcription from RNA polymerase II promoter, paraxial mesoderm formation, placenta development, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription initiation from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein localization, regulation of Wnt receptor signaling pathway, regulation of insulin secretion, regulation of pronephros size, regulation of transcription from RNA polymerase II promoter, renal glucose absorption, reproductive structure development, response to glucose stimulus, response to oxidative stress, reverse cholesterol transport cytoplasm, nucleus, photoreceptor outer segment, pronucleus, protein complex, transcription factor complex DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, double-stranded DNA binding, protein binding, protein dimerization activity, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding Human UniProtKB:P15257 HNF1B HPA UniProtKB {GO:0005515=PMID:21281489, GO:0003700=PMID:16297991, GO:0030111=GO_REF:0000019, GO:0044212=GO_REF:0000019, GO:0003705=GO_REF:0000019, GO:0048793=PMID:15355349, GO:0042663=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0060261=PMID:15355349, GO:0009952=GO_REF:0000019, GO:0001714=GO_REF:0000019, GO:0072181=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0060677=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0001822=PMID:21281489, GO:0005730=GO_REF:0000052, GO:0039020=PMID:15355349, GO:0001826=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0050673=GO_REF:0000019, GO:0009749=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0072095=GO_REF:0000019, GO:0061017=GO_REF:0000019, GO:0048557=GO_REF:0000019, GO:0031018=Reactome:REACT_13698, GO:0048754=GO_REF:0000019, GO:0045893=PMID:21281489, GO:0035565=PMID:15355349, GO:0030073=GO_REF:0000019, GO:0030902=GO_REF:0000019} P35680 Hepatocyte nuclear factor 1-beta protein 20080818 {GO:0005515=IPI, GO:0003700=IDA, GO:0030111=IEA, GO:0044212=IEA, GO:0003705=IEA, GO:0048793=IMP, GO:0042663=IEA, GO:0005634=IDA, GO:0060261=IDA, GO:0009952=IEA, GO:0001714=IEA, GO:0072181=IEA, GO:0042803=IEA, GO:0060677=IEA, GO:0045944=IEA, GO:0005667=IEA, GO:0043066=IEA, GO:0046982=IEA, GO:0001822=IDA, GO:0005730=IDA, GO:0039020=IGI, GO:0001826=IEA, GO:0000122=IEA, GO:0050673=IEA, GO:0009749=IEA, GO:0043565=IEA, GO:0072095=IEA, GO:0061017=IEA, GO:0048557=IEA, GO:0031018=TAS, GO:0048754=IEA, GO:0045893=IDA, GO:0035565=IMP, GO:0030073=IEA, GO:0030902=IEA} anterior/posterior pattern specification, branching morphogenesis of an epithelial tube, embryonic digestive tract morphogenesis, endocrine pancreas development, endodermal cell fate specification, epithelial cell proliferation, hepatoblast differentiation, hindbrain development, inner cell mass cell differentiation, insulin secretion, kidney development, mesonephric duct formation, negative regulation of apoptotic process, negative regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription initiation from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, pronephric nephron tubule development, pronephros development, regulation of Wnt receptor signaling pathway, regulation of branch elongation involved in ureteric bud branching, regulation of endodermal cell fate specification, regulation of pronephros size, response to glucose stimulus, ureteric bud elongation nucleolus, nucleus, transcription factor complex RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, protein binding, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding NOT Human HNF4A BHF-UCL UniProtKB {GO:0005515=PMID:16488887, GO:0006629=GO_REF:0000019, GO:2000189=GO_REF:0000024, GO:0010467=Reactome:REACT_71, GO:0030308=PMID:18163890, GO:0008285=PMID:18163890, GO:0006805=PMID:17827783, GO:0003700=PMID:10330009, GO:0006367=Reactome:REACT_15525, GO:0044212=PMID:16488887, GO:0003705=GO_REF:0000019, GO:0003707=GO_REF:0000002, GO:0070328=GO_REF:0000024, GO:0005634=PMID:14563941, GO:0060395=GO_REF:0000019, GO:0042803=PMID:12220494, GO:0005737=PMID:14563941, GO:0045944=PMID:17827783, GO:0010470=GO_REF:0000019, GO:0007548=GO_REF:0000019, GO:0006591=PMID:17827783, GO:0004879=GO_REF:0000002, GO:0033613=GO_REF:0000024, GO:0005504=PMID:12220494, GO:0006357=PMID:18163890, GO:0023019=GO_REF:0000019, GO:0055088=PMID:17827783, GO:0005102=PMID:12220494, GO:0042593=GO_REF:0000024, GO:0003677=PMID:10551874, GO:0009749=GO_REF:0000024, GO:0019216=PMID:10551874, GO:0043565=GO_REF:0000019, GO:0001077=GO_REF:0000024, GO:0050796=GO_REF:0000024, GO:0007596=PMID:12911579, GO:0031018=Reactome:REACT_13819, GO:0055091=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_19207, GO:0045893=PMID:16488887} P41235 Hepatocyte nuclear factor 4-alpha protein 20110311 {GO:0005515=IPI, GO:0006629=IEA, GO:2000189=ISS, GO:0010467=TAS, GO:0030308=IMP, GO:0008285=IMP, GO:0006805=IMP, GO:0003700=IDA, GO:0006367=TAS, GO:0044212=IDA, GO:0003705=IEA, GO:0003707=IEA, GO:0070328=ISS, GO:0005634=IDA, GO:0060395=IEA, GO:0042803=IDA, GO:0005737=IDA, GO:0045944=IMP, GO:0010470=IEA, GO:0007548=IEA, GO:0006591=IMP, GO:0004879=IEA, GO:0033613=ISS, GO:0005504=IDA, GO:0006357=IMP, GO:0023019=IEA, GO:0055088=IMP, GO:0005102=IDA, GO:0042593=ISS, GO:0003677=IDA, GO:0009749=ISS, GO:0019216=IDA, GO:0043565=IEA, GO:0001077=ISS, GO:0050796=ISS, GO:0007596=IDA, GO:0031018=TAS, GO:0055091=ISS, GO:0008270=IEA, GO:0005654=TAS, GO:0045893=IDA} SMAD protein signal transduction, blood coagulation, endocrine pancreas development, gene expression, glucose homeostasis, lipid homeostasis, lipid metabolic process, negative regulation of cell growth, negative regulation of cell proliferation, ornithine metabolic process, phospholipid homeostasis, positive regulation of cholesterol homeostasis, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of gastrulation, regulation of insulin secretion, regulation of lipid metabolic process, regulation of transcription from RNA polymerase II promoter, response to glucose stimulus, sex differentiation, signal transduction involved in regulation of gene expression, transcription initiation from RNA polymerase II promoter, triglyceride homeostasis, xenobiotic metabolic process cytoplasm, nucleoplasm, nucleus DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, activating transcription factor binding, fatty acid binding, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, protein binding, protein homodimerization activity, receptor binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity, transcription regulatory region DNA binding, zinc ion binding Human UniProtKB:P49698 HNF4G Reactome UniProtKB {GO:0043565=GO_REF:0000002, GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_15525, GO:0003700=PMID:8622695, GO:0006357=PMID:8622695, GO:0031018=Reactome:REACT_13819, GO:0003707=GO_REF:0000002, GO:0005654=Reactome:REACT_19207, GO:0008270=GO_REF:0000002, GO:0004879=GO_REF:0000002, GO:0045893=GO_REF:0000019} Q14541 Hepatocyte nuclear factor 4-gamma protein 20130301 {GO:0043565=IEA, GO:0010467=TAS, GO:0006367=TAS, GO:0003700=TAS, GO:0006357=TAS, GO:0031018=TAS, GO:0003707=IEA, GO:0005654=TAS, GO:0008270=IEA, GO:0004879=IEA, GO:0045893=IEA} endocrine pancreas development, gene expression, positive regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter nucleoplasm ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity, zinc ion binding Human HNMT HPA UniProtKB {GO:0043005=GO_REF:0000019, GO:0007585=PMID:7943261, GO:0002347=GO_REF:0000019, GO:0046539=GO_REF:0000003, GO:0005730=GO_REF:0000052, GO:0051384=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0006972=GO_REF:0000019, GO:0014075=GO_REF:0000019, GO:0042220=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0007420=GO_REF:0000019, GO:0070555=GO_REF:0000019} P50135 Histamine N-methyltransferase protein 20110516 {GO:0043005=IEA, GO:0007585=TAS, GO:0002347=IEA, GO:0046539=IEA, GO:0005730=IDA, GO:0051384=IEA, GO:0005634=IDA, GO:0006972=IEA, GO:0014075=IEA, GO:0042220=IEA, GO:0005737=IDA, GO:0007420=IEA, GO:0070555=IEA} brain development, hyperosmotic response, respiratory gaseous exchange, response to amine stimulus, response to cocaine, response to glucocorticoid stimulus, response to interleukin-1, response to tumor cell cytoplasm, neuron projection, nucleolus, nucleus histamine N-methyltransferase activity Human HNRNPA0 HPA UniProtKB {GO:0006397=PMID:7585247, GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0019901=PMID:20932473, GO:0003723=PMID:7585247, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006954=GO_REF:0000024, GO:0000166=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0030529=GO_REF:0000037, GO:0032496=GO_REF:0000024, GO:0017091=PMID:20932473, GO:0005654=Reactome:REACT_1935, GO:0070935=GO_REF:0000024} Q13151 Heterogeneous nuclear ribonucleoprotein A0 protein 20110516 {GO:0006397=TAS, GO:0008380=TAS, GO:0010467=TAS, GO:0019901=IPI, GO:0003723=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0006954=ISS, GO:0000166=IEA, GO:0000398=TAS, GO:0030529=IEA, GO:0032496=ISS, GO:0017091=IDA, GO:0005654=TAS, GO:0070935=ISS} 3'-UTR-mediated mRNA stabilization, RNA splicing, gene expression, inflammatory response, mRNA processing, mRNA splicing, via spliceosome, response to lipopolysaccharide nucleolus, nucleoplasm, nucleus, ribonucleoprotein complex AU-rich element binding, RNA binding, nucleotide binding, protein kinase binding NOT Human HNRNPA1 HPA UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0006397=PMID:8521471, GO:0010467=Reactome:REACT_71, GO:0003727=PMID:8521471, GO:0051170=PMID:8521471, GO:0003723=PMID:8521471, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0071013=PMID:11991638, GO:0006405=PMID:8521471, GO:0005737=GO_REF:0000052, GO:0003697=PMID:8521471, GO:0000166=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0019048=GO_REF:0000037, GO:0030529=PMID:18809582, GO:0005654=Reactome:REACT_1935, GO:0005681=PMID:9731529, GO:0045111=GO_REF:0000052, GO:0051028=GO_REF:0000037, GO:0051168=PMID:8521471} P09651 Heterogeneous nuclear ribonucleoprotein A1 protein 20120912 {GO:0008380=TAS, GO:0006397=TAS, GO:0010467=TAS, GO:0003727=IC, GO:0051170=IDA, GO:0003723=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0071013=IDA, GO:0006405=IC, GO:0005737=IDA, GO:0003697=IDA, GO:0000166=IEA, GO:0000398=TAS, GO:0019048=IEA, GO:0030529=IDA, GO:0005654=TAS, GO:0005681=IDA, GO:0045111=IDA, GO:0051028=IEA, GO:0051168=IDA} RNA export from nucleus, RNA splicing, gene expression, mRNA processing, mRNA splicing, via spliceosome, mRNA transport, nuclear export, nuclear import, virus-host interaction catalytic step 2 spliceosome, cytoplasm, intermediate filament cytoskeleton, nucleolus, nucleoplasm, nucleus, ribonucleoprotein complex, spliceosomal complex RNA binding, nucleic acid binding, nucleotide binding, single-stranded DNA binding, single-stranded RNA binding Human HNRNPA1L2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0000380=GO_REF:0000019, GO:0003723=GO_REF:0000037, GO:0005681=GO_REF:0000037, GO:0051028=GO_REF:0000037} Q32P51 Heterogeneous nuclear ribonucleoprotein A1-like 2 protein 20130413 {GO:0005737=IEA, GO:0000166=IEA, GO:0000380=IEA, GO:0003723=IEA, GO:0005681=IEA, GO:0051028=IEA} alternative mRNA splicing, via spliceosome, mRNA transport cytoplasm, spliceosomal complex RNA binding, nucleotide binding Human UniProtKB-SubCell:SL-0086 HNRNPA2B1 BHF-UCL UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:21784977, GO:0006397=PMID:2557628, GO:0010467=Reactome:REACT_71, GO:0048025=GO_REF:0000019, GO:0003723=PMID:15659580, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0050658=PMID:17004321, GO:0071013=PMID:11991638, GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0030529=PMID:2557628, GO:0005654=Reactome:REACT_1935, GO:0005681=PMID:9731529, GO:0097157=GO_REF:0000019, GO:0043047=PMID:15659580} P22626 Heterogeneous nuclear ribonucleoproteins A2/B1 protein 20121001 {GO:0008380=TAS, GO:0005515=IPI, GO:0006397=IDA, GO:0010467=TAS, GO:0048025=IEA, GO:0003723=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0050658=IDA, GO:0071013=IDA, GO:0005737=IEA, GO:0000166=IEA, GO:0000398=TAS, GO:0030529=IDA, GO:0005654=TAS, GO:0005681=IDA, GO:0097157=IEA, GO:0043047=IDA} RNA splicing, RNA transport, gene expression, mRNA processing, mRNA splicing, via spliceosome, negative regulation of mRNA splicing, via spliceosome catalytic step 2 spliceosome, cytoplasm, nucleolus, nucleoplasm, nucleus, ribonucleoprotein complex, spliceosomal complex RNA binding, nucleotide binding, pre-mRNA intronic binding, protein binding, single-stranded telomeric DNA binding Human HNRNPA3 HPA UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0000166=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0030529=PMID:8101480, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005654=Reactome:REACT_1935, GO:0005634=GO_REF:0000052, GO:0071013=PMID:11991638, GO:0003676=GO_REF:0000002} P51991 Heterogeneous nuclear ribonucleoprotein A3 protein 20101115 {GO:0008380=TAS, GO:0010467=TAS, GO:0000166=IEA, GO:0000398=TAS, GO:0030529=TAS, GO:0003723=IEA, GO:0005730=IDA, GO:0005654=TAS, GO:0005634=IDA, GO:0071013=IDA, GO:0003676=IEA} RNA splicing, gene expression, mRNA splicing, via spliceosome catalytic step 2 spliceosome, nucleolus, nucleoplasm, nucleus, ribonucleoprotein complex RNA binding, nucleic acid binding, nucleotide binding Human HNRNPAB HPA UniProtKB {GO:0043565=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0003700=GO_REF:0000024, GO:0000166=GO_REF:0000002, GO:0003723=PMID:1717314, GO:0030529=PMID:17289661, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0001837=GO_REF:0000024, GO:0045893=GO_REF:0000024, GO:0003729=PMID:8999813, GO:0003676=GO_REF:0000002} Q99729 Heterogeneous nuclear ribonucleoprotein A/B protein 20111111 {GO:0043565=ISS, GO:0005737=ISS, GO:0003700=ISS, GO:0000166=IEA, GO:0003723=TAS, GO:0030529=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0001837=ISS, GO:0045893=ISS, GO:0003729=TAS, GO:0003676=IEA} epithelial to mesenchymal transition, positive regulation of transcription, DNA-dependent cytoplasm, nucleolus, nucleus, ribonucleoprotein complex RNA binding, mRNA binding, nucleic acid binding, nucleotide binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity NOT Human HNRNPC IntAct UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:17289661, GO:0010467=Reactome:REACT_71, GO:0000166=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0003723=PMID:9731529, GO:0030529=GO_REF:0000038, GO:0005654=Reactome:REACT_1935, GO:0005681=PMID:9731529, GO:0071013=PMID:11991638, GO:0003676=GO_REF:0000002, GO:0042802=PMID:16189514} P07910 Heterogeneous nuclear ribonucleoproteins C1/C2 protein 20130415 {GO:0008380=TAS, GO:0005515=IPI, GO:0010467=TAS, GO:0000166=IEA, GO:0000398=TAS, GO:0003723=NAS, GO:0030529=IEA, GO:0005654=TAS, GO:0005681=IDA, GO:0071013=IDA, GO:0003676=IEA, GO:0042802=IPI} RNA splicing, gene expression, mRNA splicing, via spliceosome catalytic step 2 spliceosome, nucleoplasm, ribonucleoprotein complex, spliceosomal complex RNA binding, identical protein binding, nucleic acid binding, nucleotide binding, protein binding Human UniProtKB:P07910 HNRNPCL1 UniProtKB UniProtKB {GO:0000166=GO_REF:0000002, GO:0030529=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039} O60812 Heterogeneous nuclear ribonucleoprotein C-like 1 protein 20130413 {GO:0000166=IEA, GO:0030529=IEA, GO:0003723=IEA, GO:0005634=IEA} nucleus, ribonucleoprotein complex RNA binding, nucleotide binding Human UniProtKB-SubCell:SL-0191 HNRNPD HPA UniProtKB {GO:0005515=PMID:12107167, GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0043488=GO_REF:0000019, GO:0006396=PMID:10205060, GO:0006355=PMID:1433497, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=PMID:8321232, GO:0042162=PMID:8321232, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0005829=Reactome:REACT_25343, GO:0006401=PMID:10205060, GO:0000166=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0030529=PMID:17289661, GO:0005654=Reactome:REACT_1935, GO:0045893=PMID:1433497} Q14103 Heterogeneous nuclear ribonucleoprotein D0 protein 20101115 {GO:0005515=IPI, GO:0008380=TAS, GO:0010467=TAS, GO:0043488=IEA, GO:0006396=TAS, GO:0006355=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=IDA, GO:0042162=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0006351=IEA, GO:0005829=TAS, GO:0006401=TAS, GO:0000166=IEA, GO:0000398=TAS, GO:0030529=IDA, GO:0005654=TAS, GO:0045893=NAS} RNA catabolic process, RNA metabolic process, RNA processing, RNA splicing, gene expression, mRNA metabolic process, mRNA splicing, via spliceosome, positive regulation of transcription, DNA-dependent, regulation of mRNA stability, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytosol, nucleolus, nucleoplasm, nucleus, ribonucleoprotein complex RNA binding, nucleic acid binding, nucleotide binding, protein binding, telomeric DNA binding NOT Human HNRNPF HPA UniProtKB {GO:0005515=PMID:17932509, GO:0008380=Reactome:REACT_1735, GO:0006396=PMID:7499401, GO:0010467=Reactome:REACT_71, GO:0003727=PMID:20526337, GO:0003723=PMID:7499401, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0071013=PMID:11991638, GO:0005737=GO_REF:0000052, GO:0000166=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0043484=PMID:20526337, GO:0005654=Reactome:REACT_1935} P52597 Heterogeneous nuclear ribonucleoprotein F protein 20090616 {GO:0005515=IPI, GO:0008380=TAS, GO:0006396=TAS, GO:0010467=TAS, GO:0003727=IDA, GO:0003723=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0071013=IDA, GO:0005737=IDA, GO:0000166=IEA, GO:0000398=TAS, GO:0043484=IDA, GO:0005654=TAS} RNA processing, RNA splicing, gene expression, mRNA splicing, via spliceosome, regulation of RNA splicing catalytic step 2 spliceosome, cytoplasm, nucleolus, nucleoplasm, nucleus RNA binding, nucleotide binding, protein binding, single-stranded RNA binding Human HNRNPH1 HPA UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:16946708, GO:0010467=Reactome:REACT_71, GO:0006396=PMID:7499401, GO:0003723=PMID:16946708, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0015629=GO_REF:0000052, GO:0071013=PMID:11991638, GO:0008266=PMID:7499401, GO:0005737=GO_REF:0000052, GO:0000166=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0005654=Reactome:REACT_1935, GO:0043484=PMID:16946708} P31943 Heterogeneous nuclear ribonucleoprotein H protein 20101115 {GO:0008380=TAS, GO:0005515=IPI, GO:0010467=TAS, GO:0006396=TAS, GO:0003723=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0015629=IDA, GO:0071013=IDA, GO:0008266=TAS, GO:0005737=IDA, GO:0000166=IEA, GO:0000398=TAS, GO:0005654=TAS, GO:0043484=IDA} RNA processing, RNA splicing, gene expression, mRNA splicing, via spliceosome, regulation of RNA splicing actin cytoskeleton, catalytic step 2 spliceosome, cytoplasm, nucleolus, nucleoplasm, nucleus RNA binding, nucleic acid binding, nucleotide binding, poly(U) RNA binding, protein binding Human HNRNPH2 HPA UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0005737=GO_REF:0000052, GO:0000166=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0030529=PMID:18809582, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005654=Reactome:REACT_1935, GO:0015629=GO_REF:0000052} P55795 Heterogeneous nuclear ribonucleoprotein H2 protein 20101115 {GO:0008380=TAS, GO:0010467=TAS, GO:0005737=IDA, GO:0000166=IEA, GO:0000398=TAS, GO:0030529=IDA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005654=TAS, GO:0015629=IDA} RNA splicing, gene expression, mRNA splicing, via spliceosome actin cytoskeleton, cytoplasm, nucleolus, nucleoplasm, nucleus, ribonucleoprotein complex RNA binding, nucleotide binding Human HNRNPH3 HPA UniProtKB {GO:0008380=PMID:8999868, GO:0006396=PMID:8999868, GO:0000166=GO_REF:0000002, GO:0000398=PMID:10858537, GO:0003723=PMID:10858537, GO:0030529=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000038} P31942 Heterogeneous nuclear ribonucleoprotein H3 protein 20110516 {GO:0008380=TAS, GO:0006396=TAS, GO:0000166=IEA, GO:0000398=NAS, GO:0003723=NAS, GO:0030529=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA} RNA processing, RNA splicing, mRNA splicing, via spliceosome nucleolus, nucleus, ribonucleoprotein complex RNA binding, nucleic acid binding, nucleotide binding NOT Human HNRNPK HPA UniProtKB {GO:0005515=PMID:19174163, GO:0008380=Reactome:REACT_1735, GO:0006396=PMID:8107114, GO:0010467=Reactome:REACT_71, GO:0000790=PMID:20371611, GO:0003723=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0045716=PMID:20371611, GO:0000978=PMID:20371611, GO:0071013=PMID:11991638, GO:0007165=PMID:16130169, GO:0001077=PMID:20371611, GO:0005737=GO_REF:0000039, GO:0003697=PMID:20371611, GO:0000398=Reactome:REACT_467, GO:0045944=PMID:20371611, GO:0019048=GO_REF:0000037, GO:0048260=PMID:20371611, GO:0010988=PMID:20371611, GO:0005654=Reactome:REACT_1935, GO:0072369=PMID:20371611} Q5T6W5 Heterogeneous nuclear ribonucleoprotein K protein 20080205 {GO:0005515=IPI, GO:0008380=TAS, GO:0006396=TAS, GO:0010467=TAS, GO:0000790=IDA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0045716=IMP, GO:0000978=IMP, GO:0071013=IDA, GO:0007165=TAS, GO:0001077=IMP, GO:0005737=IEA, GO:0003697=TAS, GO:0000398=TAS, GO:0045944=IMP, GO:0019048=IEA, GO:0048260=IMP, GO:0010988=IMP, GO:0005654=TAS, GO:0072369=IMP} RNA processing, RNA splicing, gene expression, mRNA splicing, via spliceosome, positive regulation of low-density lipoprotein particle receptor biosynthetic process, positive regulation of receptor-mediated endocytosis, positive regulation of transcription from RNA polymerase II promoter, regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter, regulation of low-density lipoprotein particle clearance, signal transduction, virus-host interaction catalytic step 2 spliceosome, cytoplasm, nuclear chromatin, nucleolus, nucleoplasm, nucleus RNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, protein binding, single-stranded DNA binding NOT Human HNRNPL Reactome UniProtKB {GO:0006397=GO_REF:0000002, GO:0005515=PMID:11809897, GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0006396=PMID:2687284, GO:0044212=PMID:11809897, GO:0003723=GO_REF:0000037, GO:0005634=PMID:15798186, GO:0003676=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0030529=PMID:17289661, GO:0005654=Reactome:REACT_1935} P14866 Heterogeneous nuclear ribonucleoprotein L protein 20130213 {GO:0006397=IEA, GO:0005515=IPI, GO:0008380=TAS, GO:0010467=TAS, GO:0006396=TAS, GO:0044212=IDA, GO:0003723=IEA, GO:0005634=IDA, GO:0003676=IEA, GO:0005737=IEA, GO:0000166=IEA, GO:0000398=TAS, GO:0030529=IDA, GO:0005654=TAS} RNA processing, RNA splicing, gene expression, mRNA processing, mRNA splicing, via spliceosome cytoplasm, nucleoplasm, nucleus, ribonucleoprotein complex RNA binding, nucleic acid binding, nucleotide binding, protein binding, transcription regulatory region DNA binding Human HNRNPM HPA UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:19874820, GO:0010467=Reactome:REACT_71, GO:0003723=PMID:9731529, GO:0019904=PMID:11984006, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0071013=PMID:11991638, GO:0016363=PMID:19874820, GO:0042382=PMID:19874820, GO:0000166=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0005887=PMID:8088785, GO:0000380=PMID:19874820, GO:0005681=PMID:9731529, GO:0005654=PMID:19874820} P52272 Heterogeneous nuclear ribonucleoprotein M protein 20100326 {GO:0008380=TAS, GO:0005515=IPI, GO:0010467=TAS, GO:0003723=NAS, GO:0019904=IPI, GO:0005730=IDA, GO:0005634=IDA, GO:0071013=IDA, GO:0016363=IDA, GO:0042382=IDA, GO:0000166=IEA, GO:0000398=TAS, GO:0005887=TAS, GO:0000380=IMP, GO:0005681=IDA, GO:0005654=IDA} RNA splicing, alternative mRNA splicing, via spliceosome, gene expression, mRNA splicing, via spliceosome catalytic step 2 spliceosome, integral to plasma membrane, nuclear matrix, nucleolus, nucleoplasm, nucleus, paraspeckles, spliceosomal complex RNA binding, nucleotide binding, protein binding, protein domain specific binding NOT Human HNRNPR HPA UniProtKB {GO:0005515=PMID:17474147, GO:0006397=PMID:9421497, GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0003723=PMID:9421497, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000038, GO:0071013=PMID:11991638, GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0030529=GO_REF:0000038, GO:0005654=Reactome:REACT_1935, GO:0005681=PMID:9421497} Q2L7G6 Heterogeneous nuclear ribonucleoprotein R protein 20111111 {GO:0005515=IPI, GO:0006397=NAS, GO:0008380=TAS, GO:0010467=TAS, GO:0003723=NAS, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0071013=IDA, GO:0005737=IEA, GO:0000166=IEA, GO:0000398=TAS, GO:0030529=IEA, GO:0005654=TAS, GO:0005681=NAS} RNA splicing, gene expression, mRNA processing, mRNA splicing, via spliceosome catalytic step 2 spliceosome, cytoplasm, nucleolus, nucleoplasm, nucleus, ribonucleoprotein complex, spliceosomal complex RNA binding, nucleic acid binding, nucleotide binding, protein binding NOT Human HNRNPU InterPro UniProtKB {GO:0005515=PMID:19174163, GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0006396=PMID:1628625, GO:0070934=PMID:19029303, GO:0009986=GO_REF:0000039, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000002, GO:0071013=PMID:11991638, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0000398=Reactome:REACT_467, GO:0030529=PMID:17289661, GO:0005654=Reactome:REACT_1935, GO:0070937=PMID:19029303} Q5RI18 Heterogeneous nuclear ribonucleoprotein U protein 20130413 {GO:0005515=IPI, GO:0008380=TAS, GO:0010467=TAS, GO:0006396=TAS, GO:0070934=IMP, GO:0009986=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0071013=IDA, GO:0003677=IEA, GO:0005524=IEA, GO:0000398=TAS, GO:0030529=IDA, GO:0005654=TAS, GO:0070937=IDA} CRD-mediated mRNA stabilization, RNA processing, RNA splicing, gene expression, mRNA splicing, via spliceosome CRD-mediated mRNA stability complex, catalytic step 2 spliceosome, cell surface, nucleoplasm, nucleus, ribonucleoprotein complex ATP binding, DNA binding, RNA binding, protein binding Human InterPro:IPR026745 HNRNPUL1 IntAct UniProtKB {GO:0005515=PMID:15907477, GO:0008380=Reactome:REACT_1735, GO:0006396=PMID:9733834, GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0005634=PMID:11513728, GO:0009615=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0000398=Reactome:REACT_467, GO:0030529=GO_REF:0000037, GO:0005654=Reactome:REACT_1935, GO:0019899=PMID:11513728} Q9BUJ2 Heterogeneous nuclear ribonucleoprotein U-like protein 1 protein 20130415 {GO:0005515=IPI, GO:0008380=TAS, GO:0006396=TAS, GO:0010467=TAS, GO:0006355=IEA, GO:0003723=IEA, GO:0005634=IDA, GO:0009615=IEA, GO:0003676=IEA, GO:0006351=IEA, GO:0000398=TAS, GO:0030529=IEA, GO:0005654=TAS, GO:0019899=IPI} RNA processing, RNA splicing, gene expression, mRNA splicing, via spliceosome, regulation of transcription, DNA-dependent, response to virus, transcription, DNA-dependent nucleoplasm, nucleus, ribonucleoprotein complex RNA binding, enzyme binding, nucleic acid binding, protein binding Human UniProtKB:P04637 HNRNPUL2 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0005634=GO_REF:0000024, GO:0003676=GO_REF:0000002} Q1KMD3 Heterogeneous nuclear ribonucleoprotein U-like protein 2 protein 20070115 {GO:0008150=ND, GO:0005634=ISS, GO:0003676=IEA} biological_process nucleus nucleic acid binding Human HNRPDL UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0006355=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O14979 Heterogeneous nuclear ribonucleoprotein D-like protein 20130413 {GO:0005737=IEA, GO:0006355=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus DNA binding, RNA binding, nucleotide binding Human UniProtKB-SubCell:SL-0086 HNRPLL UniProtKB UniProtKB {GO:0005515=PMID:18669861, GO:0006397=GO_REF:0000002, GO:0000166=GO_REF:0000002, GO:0030529=GO_REF:0000037, GO:0003723=GO_REF:0000002, GO:0005634=GO_REF:0000002, GO:0003729=PMID:18669861, GO:0003676=GO_REF:0000002, GO:0033120=PMID:18669861} Q8WVV9 Heterogeneous nuclear ribonucleoprotein L-like protein 20090731 {GO:0005515=IPI, GO:0006397=IEA, GO:0000166=IEA, GO:0030529=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0003729=IDA, GO:0003676=IEA, GO:0033120=IDA} mRNA processing, positive regulation of RNA splicing nucleus, ribonucleoprotein complex RNA binding, mRNA binding, nucleic acid binding, nucleotide binding, protein binding Human UniProtKB:P14866 HOMER1 BHF-UCL UniProtKB {GO:0030018=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0051928=GO_REF:0000019, GO:0035418=GO_REF:0000019, GO:0048148=GO_REF:0000019, GO:0007268=PMID:9808458, GO:2001257=PMID:14505576, GO:2001256=PMID:14505576, GO:0007206=PMID:9808459, GO:0042802=GO_REF:0000019, GO:0043198=GO_REF:0000019, GO:0045211=GO_REF:0000037, GO:0097110=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0035591=PMID:14505576, GO:0048875=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0090279=GO_REF:0000019, GO:0006950=GO_REF:0000019, GO:0045177=GO_REF:0000019, GO:0048741=GO_REF:0000019, GO:0014069=GO_REF:0000039, GO:0009967=PMID:14505576, GO:0044325=PMID:14505576, GO:0051592=PMID:14505576, GO:0032947=GO_REF:0000019, GO:0031802=GO_REF:0000019, GO:0003009=GO_REF:0000019, GO:0005887=PMID:9808459, GO:0043034=GO_REF:0000019, GO:0007623=GO_REF:0000019, GO:0035094=GO_REF:0000019} Q86YM7 Homer protein homolog 1 protein 20120119 {GO:0030018=IEA, GO:0030054=IEA, GO:0051928=IEA, GO:0035418=IEA, GO:0048148=IEA, GO:0007268=TAS, GO:2001257=TAS, GO:2001256=TAS, GO:0007206=TAS, GO:0042802=IEA, GO:0043198=IEA, GO:0045211=IEA, GO:0097110=IEA, GO:0043025=IEA, GO:0035591=IC, GO:0048875=IEA, GO:0046982=IEA, GO:0090279=IEA, GO:0006950=IEA, GO:0045177=IEA, GO:0048741=IEA, GO:0014069=IEA, GO:0009967=IC, GO:0044325=IPI, GO:0051592=IDA, GO:0032947=IEA, GO:0031802=IEA, GO:0003009=IEA, GO:0005887=TAS, GO:0043034=IEA, GO:0007623=IEA, GO:0035094=IEA} behavioral response to cocaine, chemical homeostasis within a tissue, circadian rhythm, phospholipase C-activating G-protein coupled glutamate receptor signaling pathway, positive regulation of calcium ion transport, positive regulation of signal transduction, protein localization to synapse, regulation of calcium ion import, regulation of cation channel activity, regulation of store-operated calcium entry, response to calcium ion, response to nicotine, response to stress, skeletal muscle contraction, skeletal muscle fiber development, synaptic transmission Z disc, apical part of cell, cell junction, costamere, dendritic shaft, integral to plasma membrane, neuronal cell body, postsynaptic density, postsynaptic membrane identical protein binding, ion channel binding, protein complex scaffold, protein heterodimerization activity, scaffold protein binding, signaling adaptor activity, type 5 metabotropic glutamate receptor binding Human HOMER2 HPA UniProtKB {GO:0048875=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0035584=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0019904=GO_REF:0000019, GO:0007216=PMID:9808458, GO:0014069=GO_REF:0000039, GO:0048148=GO_REF:0000019, GO:0045177=GO_REF:0000019, GO:0003779=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0030160=GO_REF:0000019, GO:0008277=GO_REF:0000019, GO:0035256=GO_REF:0000019, GO:0045211=GO_REF:0000037, GO:0043025=GO_REF:0000019} Q9NSB8 Homer protein homolog 2 protein 20111111 {GO:0048875=IEA, GO:0030054=IEA, GO:0035584=IEA, GO:0046982=IEA, GO:0005886=IDA, GO:0019904=IEA, GO:0007216=TAS, GO:0014069=IEA, GO:0048148=IEA, GO:0045177=IEA, GO:0003779=IEA, GO:0042803=IEA, GO:0005737=IDA, GO:0030160=IEA, GO:0008277=IEA, GO:0035256=IEA, GO:0045211=IEA, GO:0043025=IEA} G-protein coupled glutamate receptor signaling pathway, behavioral response to cocaine, calcium-mediated signaling using intracellular calcium source, chemical homeostasis within a tissue, regulation of G-protein coupled receptor protein signaling pathway apical part of cell, cell junction, cytoplasm, neuronal cell body, plasma membrane, postsynaptic density, postsynaptic membrane G-protein coupled glutamate receptor binding, GKAP/Homer scaffold activity, actin binding, protein domain specific binding, protein heterodimerization activity, protein homodimerization activity Human HOMER3 IntAct UniProtKB {GO:0005515=PMID:18387811, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000037, GO:0045211=GO_REF:0000037, GO:0019904=GO_REF:0000019, GO:0007216=PMID:9808458, GO:0045178=GO_REF:0000019, GO:0014069=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0006605=PMID:10653696, GO:0008022=GO_REF:0000019, GO:0005829=GO_REF:0000019} Q9NSC5 Homer protein homolog 3 protein 20130415 {GO:0005515=IPI, GO:0030054=IEA, GO:0005886=IEA, GO:0045211=IEA, GO:0019904=IEA, GO:0007216=TAS, GO:0045178=IEA, GO:0014069=IEA, GO:0005575=ND, GO:0006605=TAS, GO:0008022=IEA, GO:0005829=IEA} G-protein coupled glutamate receptor signaling pathway, protein targeting basal part of cell, cell junction, cellular_component, cytosol, plasma membrane, postsynaptic density, postsynaptic membrane protein C-terminus binding, protein binding, protein domain specific binding Human UniProtKB:P05067-8 HOMEZ HPA UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037} Q8IX15 Homeobox and leucine zipper protein Homez protein 20110516 {GO:0043565=IEA, GO:0003700=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006351=IEA} transcription, DNA-dependent nucleolus, nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity NOT Human HOOK1 UniProtKB UniProtKB {GO:0008017=GO_REF:0000002, GO:0005515=PMID:18799622, GO:0030897=PMID:18799622, GO:0008333=PMID:18799622, GO:0005874=GO_REF:0000019, GO:0007286=GO_REF:0000019, GO:0000226=GO_REF:0000002, GO:0003779=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0045022=PMID:18799622, GO:0042802=PMID:18799622, GO:0005737=GO_REF:0000002, GO:0007032=PMID:18799622, GO:0007040=PMID:18799622, GO:0070695=PMID:18799622} Q9UJC3 Protein Hook homolog 1 protein 20090603 {GO:0008017=IEA, GO:0005515=IPI, GO:0030897=IDA, GO:0008333=IMP, GO:0005874=IEA, GO:0007286=IEA, GO:0000226=IEA, GO:0003779=IEA, GO:0007275=IEA, GO:0015031=IEA, GO:0045022=IMP, GO:0042802=IPI, GO:0005737=IEA, GO:0007032=IMP, GO:0007040=IMP, GO:0070695=IDA} early endosome to late endosome transport, endosome organization, endosome to lysosome transport, lysosome organization, microtubule cytoskeleton organization, multicellular organismal development, protein transport, spermatid development FHF complex, HOPS complex, cytoplasm, microtubule actin binding, identical protein binding, microtubule binding, protein binding Human UniProtKB:Q86VS8 HOOK2 IntAct UniProtKB {GO:0008017=GO_REF:0000002, GO:0005515=PMID:16189514, GO:0005813=PMID:17140400, GO:0030897=PMID:18799622, GO:0005874=GO_REF:0000037, GO:0008333=PMID:18799622, GO:0000226=GO_REF:0000002, GO:0015031=GO_REF:0000037, GO:0045022=PMID:18799622, GO:0006897=PMID:9927460, GO:0042802=PMID:18799622, GO:0005737=GO_REF:0000002, GO:0007032=PMID:18799622, GO:0007040=PMID:18799622, GO:0070695=PMID:18799622} Q96ED9 Protein Hook homolog 2 protein 20130415 {GO:0008017=IEA, GO:0005515=IPI, GO:0005813=IDA, GO:0030897=IDA, GO:0005874=IEA, GO:0008333=IMP, GO:0000226=IEA, GO:0015031=IEA, GO:0045022=IMP, GO:0006897=TAS, GO:0042802=IPI, GO:0005737=IEA, GO:0007032=IMP, GO:0007040=IMP, GO:0070695=IDA} early endosome to late endosome transport, endocytosis, endosome organization, endosome to lysosome transport, lysosome organization, microtubule cytoskeleton organization, protein transport FHF complex, HOPS complex, centrosome, cytoplasm, microtubule identical protein binding, microtubule binding, protein binding Human UniProtKB:Q8N5R6 HOOK3 HPA UniProtKB {GO:0005515=PMID:17237231, GO:0008017=PMID:11238449, GO:0005801=PMID:11238449, GO:0030897=PMID:18799622, GO:0034451=GO_REF:0000019, GO:0031122=PMID:11238449, GO:0015031=GO_REF:0000037, GO:0045022=PMID:18799622, GO:0042802=PMID:18799622, GO:0005737=GO_REF:0000052, GO:0050768=GO_REF:0000024, GO:0022027=GO_REF:0000024, GO:0071539=GO_REF:0000024, GO:0007032=PMID:18799622, GO:0051645=PMID:11238449, GO:0000242=GO_REF:0000024, GO:0070695=PMID:18799622, GO:0097150=GO_REF:0000019, GO:0005813=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0005874=GO_REF:0000037, GO:0008333=PMID:18799622, GO:0000226=GO_REF:0000002, GO:0034454=GO_REF:0000024, GO:0007040=PMID:18799622} Q86VS8 Protein Hook homolog 3 protein 20101115 {GO:0005515=IPI, GO:0008017=IDA, GO:0005801=IDA, GO:0030897=IDA, GO:0034451=IEA, GO:0031122=IMP, GO:0015031=IEA, GO:0045022=IMP, GO:0042802=IPI, GO:0005737=IDA, GO:0050768=ISS, GO:0022027=ISS, GO:0071539=ISS, GO:0007032=IMP, GO:0051645=IMP, GO:0000242=ISS, GO:0070695=IDA, GO:0097150=IEA, GO:0005813=IDA, GO:0005794=IDA, GO:0005874=IEA, GO:0008333=IMP, GO:0000226=IEA, GO:0034454=ISS, GO:0007040=IMP} Golgi localization, cytoplasmic microtubule organization, early endosome to late endosome transport, endosome organization, endosome to lysosome transport, interkinetic nuclear migration, lysosome organization, microtubule anchoring at centrosome, microtubule cytoskeleton organization, negative regulation of neurogenesis, neuronal stem cell maintenance, protein localization to centrosome, protein transport FHF complex, Golgi apparatus, HOPS complex, centriolar satellite, centrosome, cis-Golgi network, cytoplasm, microtubule, pericentriolar material identical protein binding, microtubule binding, protein binding Human HOPX MGI UniProtKB {GO:0016575=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0048286=GO_REF:0000019, GO:0008016=GO_REF:0000019, GO:0043393=GO_REF:0000019, GO:0005634=PMID:17192267, GO:0000122=GO_REF:0000019, GO:0001829=PMID:17576768, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0007507=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0043415=GO_REF:0000019, GO:0051155=GO_REF:0000019, GO:0045596=PMID:17576768} Q9BPY8 Homeodomain-only protein protein 20101102 {GO:0016575=IEA, GO:0003700=IEA, GO:0048286=IEA, GO:0008016=IEA, GO:0043393=IEA, GO:0005634=IDA, GO:0000122=IEA, GO:0001829=IDA, GO:0003677=IEA, GO:0006351=IEA, GO:0007507=IEA, GO:0043565=IEA, GO:0043415=IEA, GO:0051155=IEA, GO:0045596=IDA} heart development, histone deacetylation, lung alveolus development, negative regulation of cell differentiation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of skeletal muscle tissue regeneration, positive regulation of striated muscle cell differentiation, regulation of heart contraction, regulation of protein binding, transcription, DNA-dependent, trophectodermal cell differentiation nucleus DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human HOXA1 PINC UniProtKB {GO:0003700=GO_REF:0000002, GO:0060876=PMID:16155570, GO:0007634=PMID:16155570, GO:0007605=PMID:16155570, GO:0048844=PMID:16155570, GO:0005634=GO_REF:0000039, GO:0048702=PMID:16155570, GO:0009952=GO_REF:0000019, GO:0021599=PMID:16155570, GO:0009653=PMID:16155570, GO:0050905=PMID:16155570, GO:0045944=GO_REF:0000019, GO:0090102=PMID:16155570, GO:0090103=PMID:16155570, GO:0042473=PMID:16155570, GO:0048839=PMID:16155570, GO:0021953=GO_REF:0000019, GO:0021569=GO_REF:0000019, GO:0007275=PMID:7622051, GO:0060840=PMID:16155570, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0021571=GO_REF:0000019, GO:0021570=GO_REF:0000019, GO:0008045=GO_REF:0000019, GO:0021754=GO_REF:0000019, GO:0050890=PMID:16155570, GO:0050795=PMID:16155570, GO:0021612=GO_REF:0000019} P49639 Homeobox protein Hox-A1 protein 20030904 {GO:0003700=IEA, GO:0060876=IMP, GO:0007634=IDA, GO:0007605=IDA, GO:0048844=IMP, GO:0005634=IEA, GO:0048702=IMP, GO:0009952=IEA, GO:0021599=IMP, GO:0009653=IMP, GO:0050905=IDA, GO:0045944=IEA, GO:0090102=IMP, GO:0090103=IMP, GO:0042473=IDA, GO:0048839=IMP, GO:0021953=IEA, GO:0021569=IEA, GO:0007275=TAS, GO:0060840=IMP, GO:0006351=IEA, GO:0043565=IEA, GO:0021571=IEA, GO:0021570=IEA, GO:0008045=IEA, GO:0021754=IEA, GO:0050890=IDA, GO:0050795=IDA, GO:0021612=IEA} abducens nerve formation, anatomical structure morphogenesis, anterior/posterior pattern specification, artery development, artery morphogenesis, central nervous system neuron differentiation, cochlea development, cochlea morphogenesis, cognition, embryonic neurocranium morphogenesis, facial nerve structural organization, facial nucleus development, inner ear development, motor neuron axon guidance, multicellular organismal development, neuromuscular process, optokinetic behavior, outer ear morphogenesis, positive regulation of transcription from RNA polymerase II promoter, regulation of behavior, rhombomere 3 development, rhombomere 4 development, rhombomere 5 development, semicircular canal formation, sensory perception of sound, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human HOXA10 IntAct UniProtKB {GO:0005515=PMID:18692240, GO:0043565=GO_REF:0000002, GO:0005667=GO_REF:0000019, GO:0001501=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0007275=PMID:8972230, GO:0009954=GO_REF:0000019, GO:0007283=PMID:7700356, GO:0030326=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0006351=GO_REF:0000037} P31260 Homeobox protein Hox-A10 protein 20130415 {GO:0005515=IPI, GO:0043565=IEA, GO:0005667=IEA, GO:0001501=IEA, GO:0003700=IEA, GO:0007275=TAS, GO:0009954=IEA, GO:0007283=TAS, GO:0030326=IEA, GO:0009952=IEA, GO:0006351=IEA} anterior/posterior pattern specification, embryonic limb morphogenesis, multicellular organismal development, proximal/distal pattern formation, skeletal system development, spermatogenesis, transcription, DNA-dependent transcription factor complex protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:P17947 HOXA11 HPA UniProtKB {GO:0001656=GO_REF:0000019, GO:0001658=GO_REF:0000024, GO:0003700=GO_REF:0000002, GO:0009954=GO_REF:0000019, GO:0001759=GO_REF:0000019, GO:0009953=GO_REF:0000024, GO:0030326=GO_REF:0000024, GO:0009952=GO_REF:0000019, GO:0009653=PMID:9745033, GO:0005737=GO_REF:0000052, GO:0048589=GO_REF:0000024, GO:0032993=GO_REF:0000024, GO:0060351=GO_REF:0000024, GO:0032332=GO_REF:0000024, GO:0005667=GO_REF:0000024, GO:0010720=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0007275=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0043234=GO_REF:0000024, GO:0001501=GO_REF:0000024, GO:0007501=GO_REF:0000024, GO:0060272=GO_REF:0000019, GO:0045893=GO_REF:0000024, GO:0042733=GO_REF:0000019} P31270 Homeobox protein Hox-A11 protein 20110516 {GO:0001656=IEA, GO:0001658=ISS, GO:0003700=IEA, GO:0009954=IEA, GO:0001759=IEA, GO:0009953=ISS, GO:0030326=ISS, GO:0009952=IEA, GO:0009653=TAS, GO:0005737=IDA, GO:0048589=ISS, GO:0032993=ISS, GO:0060351=ISS, GO:0032332=ISS, GO:0005667=ISS, GO:0010720=ISS, GO:0005730=IDA, GO:0007275=ISS, GO:0006351=IEA, GO:0043565=IEA, GO:0043234=ISS, GO:0001501=ISS, GO:0007501=ISS, GO:0060272=IEA, GO:0045893=ISS, GO:0042733=IEA} anatomical structure morphogenesis, anterior/posterior pattern specification, branching involved in ureteric bud morphogenesis, cartilage development involved in endochondral bone morphogenesis, developmental growth, dorsal/ventral pattern formation, embryonic digit morphogenesis, embryonic limb morphogenesis, embryonic skeletal joint morphogenesis, mesodermal cell fate specification, metanephros development, multicellular organismal development, organ induction, positive regulation of cell development, positive regulation of chondrocyte differentiation, positive regulation of transcription, DNA-dependent, proximal/distal pattern formation, skeletal system development, transcription, DNA-dependent cytoplasm, nucleolus, protein complex, protein-DNA complex, transcription factor complex sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human HOXA13 PINC UniProtKB {GO:0048839=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0044212=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0048844=GO_REF:0000019, GO:0003281=GO_REF:0000019, GO:0045840=GO_REF:0000019, GO:0060847=GO_REF:0000019, GO:0003677=PMID:9020844, GO:0006351=GO_REF:0000037, GO:0060442=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0030539=GO_REF:0000019, GO:0001501=PMID:9020844, GO:0001894=GO_REF:0000019, GO:0001886=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0035115=GO_REF:0000019, GO:0030510=GO_REF:0000019, GO:0001570=GO_REF:0000019} P31271 Homeobox protein Hox-A13 protein 20030904 {GO:0048839=IEA, GO:0003700=IEA, GO:0043065=IEA, GO:0044212=IEA, GO:0005634=IEA, GO:0048844=IEA, GO:0003281=IEA, GO:0045840=IEA, GO:0060847=IEA, GO:0003677=TAS, GO:0006351=IEA, GO:0060442=IEA, GO:0043565=IEA, GO:0030539=IEA, GO:0001501=TAS, GO:0001894=IEA, GO:0001886=IEA, GO:0045944=IEA, GO:0035115=IEA, GO:0030510=IEA, GO:0001570=IEA} artery morphogenesis, branching involved in prostate gland morphogenesis, embryonic forelimb morphogenesis, endothelial cell fate specification, endothelial cell morphogenesis, inner ear development, male genitalia development, positive regulation of apoptotic process, positive regulation of mitosis, positive regulation of transcription from RNA polymerase II promoter, regulation of BMP signaling pathway, skeletal system development, tissue homeostasis, transcription, DNA-dependent, vasculogenesis, ventricular septum development nucleus DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding Human HOXA2 HPA UniProtKB {GO:0003700=GO_REF:0000002, GO:0007379=GO_REF:0000019, GO:0001709=GO_REF:0000019, GO:0021658=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0021568=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0048703=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0009953=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000019, GO:0008045=GO_REF:0000019, GO:0045665=GO_REF:0000019, GO:0002076=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0035284=GO_REF:0000019, GO:0042474=GO_REF:0000019} O43364 Homeobox protein Hox-A2 protein 20101115 {GO:0003700=IEA, GO:0007379=IEA, GO:0001709=IEA, GO:0021658=IEA, GO:0005730=IDA, GO:0021568=IEA, GO:0005634=IDA, GO:0048703=IEA, GO:0000122=IEA, GO:0009953=IEA, GO:0009952=IEA, GO:0006351=IEA, GO:0043565=IEA, GO:0008045=IEA, GO:0045665=IEA, GO:0002076=IEA, GO:0045944=IEA, GO:0035284=IEA, GO:0042474=IEA} anterior/posterior pattern specification, brain segmentation, cell fate determination, dorsal/ventral pattern formation, embryonic viscerocranium morphogenesis, middle ear morphogenesis, motor neuron axon guidance, negative regulation of neuron differentiation, negative regulation of transcription from RNA polymerase II promoter, osteoblast development, positive regulation of transcription from RNA polymerase II promoter, rhombomere 2 development, rhombomere 3 morphogenesis, segment specification, transcription, DNA-dependent nucleolus, nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity NOT Human HOXA3 HPA UniProtKB {GO:0008284=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0051216=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0048538=GO_REF:0000019, GO:0048704=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0001525=PMID:17972163, GO:0030878=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0048645=GO_REF:0000019, GO:0060017=GO_REF:0000019, GO:0021615=GO_REF:0000019, GO:0001974=GO_REF:0000019, GO:0071837=GO_REF:0000019, GO:0010159=GO_REF:0000019} O43365 Homeobox protein Hox-A3 protein 20101115 {GO:0008284=IEA, GO:0003700=IEA, GO:0051216=IEA, GO:0005730=IDA, GO:0048538=IEA, GO:0048704=IEA, GO:0005634=IDA, GO:0001525=IEP, GO:0030878=IEA, GO:0009952=IEA, GO:0006351=IEA, GO:0043565=IEA, GO:0048645=IEA, GO:0060017=IEA, GO:0021615=IEA, GO:0001974=IEA, GO:0071837=IEA, GO:0010159=IEA} angiogenesis, anterior/posterior pattern specification, blood vessel remodeling, cartilage development, embryonic skeletal system morphogenesis, glossopharyngeal nerve morphogenesis, organ formation, parathyroid gland development, positive regulation of cell proliferation, specification of organ position, thymus development, thyroid gland development, transcription, DNA-dependent nucleolus, nucleus HMG box domain binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity NOT Human HOXA5 UniProtKB UniProtKB {GO:0005515=PMID:15545268, GO:0003700=PMID:10879542, GO:0048704=GO_REF:0000019, GO:0005634=PMID:15545268, GO:0010870=PMID:10875927, GO:0030878=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0060574=GO_REF:0000019, GO:0003016=GO_REF:0000019, GO:0060644=GO_REF:0000019, GO:0045639=PMID:10397719, GO:0035264=GO_REF:0000019, GO:0045944=PMID:10879542, GO:0060435=GO_REF:0000019, GO:0043065=PMID:10879542, GO:0048286=GO_REF:0000019, GO:0060764=GO_REF:0000019, GO:0003677=PMID:8657138, GO:0006351=GO_REF:0000037, GO:0033599=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0060441=GO_REF:0000019, GO:0045647=PMID:10397719, GO:0016477=GO_REF:0000019, GO:0060638=GO_REF:0000019, GO:0016525=PMID:17957028, GO:0060484=GO_REF:0000019, GO:0060535=GO_REF:0000019, GO:0060749=GO_REF:0000019, GO:0060480=GO_REF:0000019} P20719 Homeobox protein Hox-A5 protein 20100322 {GO:0005515=IPI, GO:0003700=IDA, GO:0048704=IEA, GO:0005634=IDA, GO:0010870=IDA, GO:0030878=IEA, GO:0009952=IEA, GO:0060574=IEA, GO:0003016=IEA, GO:0060644=IEA, GO:0045639=IDA, GO:0035264=IEA, GO:0045944=IDA, GO:0060435=IEA, GO:0043065=IDA, GO:0048286=IEA, GO:0060764=IEA, GO:0003677=IDA, GO:0006351=IEA, GO:0033599=IEA, GO:0043565=IEA, GO:0060441=IEA, GO:0045647=IDA, GO:0016477=IEA, GO:0060638=IEA, GO:0016525=IMP, GO:0060484=IEA, GO:0060535=IEA, GO:0060749=IEA, GO:0060480=IEA} anterior/posterior pattern specification, bronchiole development, cell migration, cell-cell signaling involved in mammary gland development, embryonic skeletal system morphogenesis, epithelial tube branching involved in lung morphogenesis, intestinal epithelial cell maturation, lung alveolus development, lung goblet cell differentiation, lung-associated mesenchyme development, mammary gland alveolus development, mammary gland epithelial cell differentiation, mesenchymal-epithelial cell signaling, multicellular organism growth, negative regulation of angiogenesis, negative regulation of erythrocyte differentiation, positive regulation of apoptotic process, positive regulation of myeloid cell differentiation, positive regulation of receptor biosynthetic process, positive regulation of transcription from RNA polymerase II promoter, regulation of mammary gland epithelial cell proliferation, respiratory system process, thyroid gland development, trachea cartilage morphogenesis, transcription, DNA-dependent nucleus DNA binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human HOXA6 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0048704=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0006351=GO_REF:0000037} P31267 Homeobox protein Hox-A6 protein 20130413 {GO:0043565=IEA, GO:0003700=IEA, GO:0005634=IEA, GO:0048704=IEA, GO:0009952=IEA, GO:0006351=IEA} anterior/posterior pattern specification, embryonic skeletal system morphogenesis, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0191 HOXA7 MGI UniProtKB {GO:0003700=GO_REF:0000019, GO:0005634=PMID:11435435, GO:0048704=GO_REF:0000019, GO:0000122=PMID:11435435, GO:0001525=PMID:17972163, GO:0009952=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0045617=PMID:11435435, GO:0048863=GO_REF:0000019, GO:0043565=PMID:11435435, GO:0045656=PMID:14704364, GO:0045944=GO_REF:0000019, GO:0002686=PMID:14704364, GO:0045892=PMID:11435435, GO:0008134=PMID:18973687, GO:0001953=PMID:14704364} P31268 Homeobox protein Hox-A7 protein 20080608 {GO:0003700=IEA, GO:0005634=IC, GO:0048704=IEA, GO:0000122=IDA, GO:0001525=IEP, GO:0009952=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0045617=IDA, GO:0048863=IEA, GO:0043565=IDA, GO:0045656=IDA, GO:0045944=IEA, GO:0002686=IDA, GO:0045892=IDA, GO:0008134=IPI, GO:0001953=IDA} angiogenesis, anterior/posterior pattern specification, embryonic skeletal system morphogenesis, negative regulation of cell-matrix adhesion, negative regulation of keratinocyte differentiation, negative regulation of leukocyte migration, negative regulation of monocyte differentiation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of transcription from RNA polymerase II promoter, stem cell differentiation, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human HOXA9 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0005667=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0048706=GO_REF:0000019, GO:0007275=PMID:8563754, GO:0005634=GO_REF:0000054, GO:0009954=GO_REF:0000019, GO:0030879=GO_REF:0000019, GO:0060216=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0005737=GO_REF:0000019, GO:0045638=GO_REF:0000024, GO:0042118=PMID:22269951, GO:0035115=GO_REF:0000019, GO:0019899=PMID:22269951} P31269 Homeobox protein Hox-A9 protein 20130415 {GO:0005515=IPI, GO:0005667=IEA, GO:0003700=IEA, GO:0048706=IEA, GO:0007275=TAS, GO:0005634=IDA, GO:0009954=IEA, GO:0030879=IEA, GO:0060216=IEA, GO:0009952=IEA, GO:0006351=IEA, GO:0043565=IEA, GO:0005737=IEA, GO:0045638=ISS, GO:0042118=IMP, GO:0035115=IEA, GO:0019899=IPI} anterior/posterior pattern specification, definitive hemopoiesis, embryonic forelimb morphogenesis, embryonic skeletal system development, endothelial cell activation, mammary gland development, multicellular organismal development, negative regulation of myeloid cell differentiation, proximal/distal pattern formation, transcription, DNA-dependent cytoplasm, nucleus, transcription factor complex enzyme binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:Q15654 HOXB1 HPA UniProtKB {GO:0007389=PMID:10052460, GO:0006355=PMID:10052460, GO:0003700=GO_REF:0000029, GO:0019904=PMID:10052460, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0048704=GO_REF:0000019, GO:0007275=PMID:10052460, GO:0009952=GO_REF:0000019, GO:0003677=PMID:10052460, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000019, GO:0021571=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0021570=GO_REF:0000019, GO:0021754=GO_REF:0000019, GO:0048646=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0021612=GO_REF:0000019} Q4VB03 Homeobox protein Hox-B1 protein 20111111 {GO:0007389=TAS, GO:0006355=TAS, GO:0003700=NAS, GO:0019904=IPI, GO:0005730=IDA, GO:0005634=IDA, GO:0048704=IEA, GO:0007275=NAS, GO:0009952=IEA, GO:0003677=IDA, GO:0006351=IEA, GO:0043565=IEA, GO:0021571=IEA, GO:0005737=IDA, GO:0021570=IEA, GO:0021754=IEA, GO:0048646=IEA, GO:0045944=IEA, GO:0021612=IEA} anatomical structure formation involved in morphogenesis, anterior/posterior pattern specification, embryonic skeletal system morphogenesis, facial nerve structural organization, facial nucleus development, multicellular organismal development, pattern specification process, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, rhombomere 4 development, rhombomere 5 development, transcription, DNA-dependent cytoplasm, nucleolus, nucleus DNA binding, protein domain specific binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human HOXB13 PINC UniProtKB {GO:0043565=GO_REF:0000002, GO:0005667=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0008544=PMID:9665387, GO:0060743=GO_REF:0000019, GO:0009611=PMID:9665387, GO:0001525=PMID:17972163, GO:0033574=GO_REF:0000019, GO:0040008=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0060527=GO_REF:0000019} Q92826 Homeobox protein Hox-B13 protein 20030904 {GO:0043565=IEA, GO:0005667=IEA, GO:0003700=IEA, GO:0008544=TAS, GO:0060743=IEA, GO:0009611=TAS, GO:0001525=IEP, GO:0033574=IEA, GO:0040008=IEA, GO:0006351=IEA, GO:0060527=IEA} angiogenesis, epidermis development, epithelial cell maturation involved in prostate gland development, prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis, regulation of growth, response to testosterone stimulus, response to wounding, transcription, DNA-dependent transcription factor complex sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human HOXB2 PINC UniProtKB {GO:0003700=GO_REF:0000002, GO:0002011=GO_REF:0000019, GO:0008015=PMID:7876223, GO:0021569=GO_REF:0000019, GO:0048704=GO_REF:0000019, GO:0048857=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0007275=PMID:7876223, GO:0009953=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0021570=GO_REF:0000019, GO:0021612=GO_REF:0000019} P14652 Homeobox protein Hox-B2 protein 20030904 {GO:0003700=IEA, GO:0002011=IEA, GO:0008015=TAS, GO:0021569=IEA, GO:0048704=IEA, GO:0048857=IEA, GO:0005634=IEA, GO:0007275=TAS, GO:0009953=IEA, GO:0009952=IEA, GO:0006351=IEA, GO:0043565=IEA, GO:0021570=IEA, GO:0021612=IEA} anterior/posterior pattern specification, blood circulation, dorsal/ventral pattern formation, embryonic skeletal system morphogenesis, facial nerve structural organization, morphogenesis of an epithelial sheet, multicellular organismal development, neural nucleus development, rhombomere 3 development, rhombomere 4 development, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human HOXB3 UniProtKB UniProtKB {GO:0003700=GO_REF:0000002, GO:0021546=GO_REF:0000019, GO:0051216=GO_REF:0000019, GO:0048704=GO_REF:0000019, GO:0060216=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0001525=PMID:17972163, GO:0000122=GO_REF:0000019, GO:0030878=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0000979=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0021615=GO_REF:0000019, GO:0050767=GO_REF:0000019, GO:0060324=GO_REF:0000019} P14651 Homeobox protein Hox-B3 protein 20100323 {GO:0003700=IEA, GO:0021546=IEA, GO:0051216=IEA, GO:0048704=IEA, GO:0060216=IEA, GO:0005634=IEA, GO:0001525=IEP, GO:0000122=IEA, GO:0030878=IEA, GO:0009952=IEA, GO:0000979=IEA, GO:0006351=IEA, GO:0043565=IEA, GO:0021615=IEA, GO:0050767=IEA, GO:0060324=IEA} angiogenesis, anterior/posterior pattern specification, cartilage development, definitive hemopoiesis, embryonic skeletal system morphogenesis, face development, glossopharyngeal nerve morphogenesis, negative regulation of transcription from RNA polymerase II promoter, regulation of neurogenesis, rhombomere development, thyroid gland development, transcription, DNA-dependent nucleus RNA polymerase II core promoter sequence-specific DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human HOXB4 BHF-UCL UniProtKB {GO:0048103=GO_REF:0000019, GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000029, GO:0002011=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:2000738=PMID:18932205, GO:0007275=GO_REF:0000029, GO:0048704=GO_REF:0000019, GO:0060216=GO_REF:0000019, GO:0005634=GO_REF:0000029, GO:0000122=GO_REF:0000019, GO:0048539=GO_REF:0000019, GO:0060218=PMID:18932205, GO:0009952=GO_REF:0000019, GO:0048536=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0045944=PMID:18932205} P17483 Homeobox protein Hox-B4 protein 20121024 {GO:0048103=IEA, GO:0006355=NAS, GO:0003700=NAS, GO:0002011=IEA, GO:0008283=IEA, GO:2000738=IDA, GO:0007275=NAS, GO:0048704=IEA, GO:0060216=IEA, GO:0005634=NAS, GO:0000122=IEA, GO:0048539=IEA, GO:0060218=IDA, GO:0009952=IEA, GO:0048536=IEA, GO:0006351=IEA, GO:0043565=IEA, GO:0045944=IDA} anterior/posterior pattern specification, bone marrow development, cell proliferation, definitive hemopoiesis, embryonic skeletal system morphogenesis, hematopoietic stem cell differentiation, morphogenesis of an epithelial sheet, multicellular organismal development, negative regulation of transcription from RNA polymerase II promoter, positive regulation of stem cell differentiation, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, somatic stem cell division, spleen development, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human HOXB5 PINC UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0048704=GO_REF:0000019, GO:0045446=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0009653=PMID:3000607, GO:0006351=GO_REF:0000037} P09067 Homeobox protein Hox-B5 protein 20031119 {GO:0043565=IEA, GO:0003700=IEA, GO:0005634=IEA, GO:0048704=IEA, GO:0045446=IEA, GO:0009952=IEA, GO:0009653=TAS, GO:0006351=IEA} anatomical structure morphogenesis, anterior/posterior pattern specification, embryonic skeletal system morphogenesis, endothelial cell differentiation, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human HOXB6 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000029, GO:0034101=GO_REF:0000019, GO:0005634=GO_REF:0000029, GO:0048704=GO_REF:0000019, GO:0008595=GO_REF:0000029, GO:0006351=GO_REF:0000037} P17509 Homeobox protein Hox-B6 protein 20021104 {GO:0043565=IEA, GO:0006355=NAS, GO:0003700=NAS, GO:0034101=IEA, GO:0005634=NAS, GO:0048704=IEA, GO:0008595=NAS, GO:0006351=IEA} anterior/posterior axis specification, embryo, embryonic skeletal system morphogenesis, erythrocyte homeostasis, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human HOXB7 HPA UniProtKB {GO:0005515=PMID:17308091, GO:0006355=PMID:1678287, GO:0003700=PMID:1678287, GO:0005730=GO_REF:0000052, GO:0048704=GO_REF:0000019, GO:0007275=PMID:2885844, GO:0005634=GO_REF:0000052, GO:0009952=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0030099=GO_REF:0000019, GO:0090190=GO_REF:0000019} P09629 Homeobox protein Hox-B7 protein 20120912 {GO:0005515=IPI, GO:0006355=NAS, GO:0003700=NAS, GO:0005730=IDA, GO:0048704=IEA, GO:0007275=NAS, GO:0005634=IDA, GO:0009952=IEA, GO:0006351=IEA, GO:0043565=IEA, GO:0005737=IDA, GO:0030099=IEA, GO:0090190=IEA} anterior/posterior pattern specification, embryonic skeletal system morphogenesis, multicellular organismal development, myeloid cell differentiation, positive regulation of branching involved in ureteric bud morphogenesis, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleolus, nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human HOXB8 UniProtKB UniProtKB {GO:0008344=GO_REF:0000019, GO:0000976=GO_REF:0000002, GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000029, GO:0048704=GO_REF:0000019, GO:0005634=GO_REF:0000029, GO:0007275=GO_REF:0000029, GO:0009952=GO_REF:0000019, GO:0019233=GO_REF:0000019, GO:0021516=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0045638=GO_REF:0000024, GO:0007625=GO_REF:0000019} P17481 Homeobox protein Hox-B8 protein 20121109 {GO:0008344=IEA, GO:0000976=IEA, GO:0006355=NAS, GO:0003700=NAS, GO:0048704=IEA, GO:0005634=NAS, GO:0007275=NAS, GO:0009952=IEA, GO:0019233=IEA, GO:0021516=IEA, GO:0006351=IEA, GO:0045638=ISS, GO:0007625=IEA} adult locomotory behavior, anterior/posterior pattern specification, dorsal spinal cord development, embryonic skeletal system morphogenesis, grooming behavior, multicellular organismal development, negative regulation of myeloid cell differentiation, regulation of transcription, DNA-dependent, sensory perception of pain, transcription, DNA-dependent nucleus sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding Human UniProtKB:P09632 HOXB9 HPA UniProtKB {GO:0005515=PMID:19060904, GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000029, GO:0005730=GO_REF:0000052, GO:0048706=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0030879=GO_REF:0000019, GO:0007275=GO_REF:0000029, GO:0009952=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0005739=GO_REF:0000052, GO:0043565=GO_REF:0000002, GO:0060326=PMID:19576624, GO:0045944=GO_REF:0000019, GO:0060070=PMID:19576624} P17482 Homeobox protein Hox-B9 protein 20101115 {GO:0005515=IPI, GO:0006355=NAS, GO:0003700=NAS, GO:0005730=IDA, GO:0048706=IEA, GO:0005634=IDA, GO:0030879=IEA, GO:0007275=NAS, GO:0009952=IEA, GO:0006351=IEA, GO:0005739=IDA, GO:0043565=IEA, GO:0060326=IDA, GO:0045944=IEA, GO:0060070=IMP} anterior/posterior pattern specification, canonical Wnt receptor signaling pathway, cell chemotaxis, embryonic skeletal system development, mammary gland development, multicellular organismal development, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription, DNA-dependent mitochondrion, nucleolus, nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human HOXC10 PINC UniProtKB {GO:0043565=GO_REF:0000002, GO:0050905=GO_REF:0000019, GO:0008284=PMID:10835276, GO:0019907=PMID:11445587, GO:0001501=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0021520=GO_REF:0000019, GO:0009954=GO_REF:0000019, GO:0030326=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q9NYD6 Homeobox protein Hox-C10 protein 20030904 {GO:0043565=IEA, GO:0050905=IEA, GO:0008284=TAS, GO:0019907=IDA, GO:0001501=IEA, GO:0003700=IEA, GO:0021520=IEA, GO:0009954=IEA, GO:0030326=IEA, GO:0009952=IEA, GO:0006351=IEA} anterior/posterior pattern specification, embryonic limb morphogenesis, neuromuscular process, positive regulation of cell proliferation, proximal/distal pattern formation, skeletal system development, spinal cord motor neuron cell fate specification, transcription, DNA-dependent cyclin-dependent protein kinase activating kinase holoenzyme complex sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human HOXC11 HPA UniProtKB {GO:0001656=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0009954=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0001759=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0005739=GO_REF:0000052, GO:0043565=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0007492=PMID:9582375, GO:0060272=GO_REF:0000019, GO:0042733=GO_REF:0000019} O43248 Homeobox protein Hox-C11 protein 20110516 {GO:0001656=IEA, GO:0003700=IEA, GO:0005730=IDA, GO:0009954=IEA, GO:0005634=IDA, GO:0001759=IEA, GO:0009952=IEA, GO:0006351=IEA, GO:0005739=IDA, GO:0043565=IEA, GO:0005737=IDA, GO:0007492=TAS, GO:0060272=IEA, GO:0042733=IEA} anterior/posterior pattern specification, embryonic digit morphogenesis, embryonic skeletal joint morphogenesis, endoderm development, metanephros development, organ induction, proximal/distal pattern formation, transcription, DNA-dependent cytoplasm, mitochondrion, nucleolus, nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human HOXC13 IntAct UniProtKB {GO:0005515=PMID:18692240, GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000029, GO:0007275=GO_REF:0000029, GO:0005634=GO_REF:0000029, GO:0009952=GO_REF:0000019, GO:0009653=PMID:10835276, GO:0043587=GO_REF:0000019, GO:0001942=GO_REF:0000019, GO:0006351=GO_REF:0000037} P31276 Homeobox protein Hox-C13 protein 20130415 {GO:0005515=IPI, GO:0043565=IEA, GO:0003700=NAS, GO:0007275=NAS, GO:0005634=NAS, GO:0009952=IEA, GO:0009653=TAS, GO:0043587=IEA, GO:0001942=IEA, GO:0006351=IEA} anatomical structure morphogenesis, anterior/posterior pattern specification, hair follicle development, multicellular organismal development, tongue morphogenesis, transcription, DNA-dependent nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:P32519 HOXC4 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000029, GO:0051216=GO_REF:0000019, GO:0071837=GO_REF:0000019, GO:0007275=GO_REF:0000029, GO:0005634=GO_REF:0000029, GO:0009952=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0048562=GO_REF:0000019} P09017 Homeobox protein Hox-C4 protein 20021104 {GO:0043565=IEA, GO:0006355=NAS, GO:0003700=NAS, GO:0051216=IEA, GO:0071837=IEA, GO:0007275=NAS, GO:0005634=NAS, GO:0009952=IEA, GO:0006351=IEA, GO:0048562=IEA} anterior/posterior pattern specification, cartilage development, embryonic organ morphogenesis, multicellular organismal development, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus HMG box domain binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human HOXC5 HPA UniProtKB {GO:0043565=GO_REF:0000002, GO:0030054=GO_REF:0000052, GO:0003700=GO_REF:0000002, GO:0006357=PMID:1346761, GO:0005730=GO_REF:0000052, GO:0048706=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0009952=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q00444 Homeobox protein Hox-C5 protein 20100326 {GO:0043565=IEA, GO:0030054=IDA, GO:0003700=IEA, GO:0006357=TAS, GO:0005730=IDA, GO:0048706=IEA, GO:0005634=IDA, GO:0009952=IEA, GO:0006351=IEA} anterior/posterior pattern specification, embryonic skeletal system development, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cell junction, nucleolus, nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human HOXC6 PINC UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0006357=PMID:8870653, GO:0003714=PMID:8870653, GO:0048706=GO_REF:0000019, GO:0007275=PMID:8870653, GO:0005634=GO_REF:0000039, GO:0009952=GO_REF:0000019, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037} P09630 Homeobox protein Hox-C6 protein 20030904 {GO:0043565=IEA, GO:0003700=IEA, GO:0006357=TAS, GO:0003714=TAS, GO:0048706=IEA, GO:0007275=TAS, GO:0005634=IEA, GO:0009952=IEA, GO:0003677=IEA, GO:0006351=IEA} anterior/posterior pattern specification, embryonic skeletal system development, multicellular organismal development, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human HOXC8 UniProtKB UniProtKB {GO:0006355=GO_REF:0000029, GO:0000976=GO_REF:0000002, GO:0003700=GO_REF:0000029, GO:0030182=GO_REF:0000019, GO:0048705=GO_REF:0000019, GO:0007275=GO_REF:0000029, GO:0005634=GO_REF:0000029, GO:0000122=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0006351=GO_REF:0000037} P31273 Homeobox protein Hox-C8 protein 20021104 {GO:0006355=NAS, GO:0000976=IEA, GO:0003700=NAS, GO:0030182=IEA, GO:0048705=IEA, GO:0007275=NAS, GO:0005634=NAS, GO:0000122=IEA, GO:0009952=IEA, GO:0006351=IEA} anterior/posterior pattern specification, multicellular organismal development, negative regulation of transcription from RNA polymerase II promoter, neuron differentiation, regulation of transcription, DNA-dependent, skeletal system morphogenesis, transcription, DNA-dependent nucleus sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding Human HOXC9 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0048704=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0006351=GO_REF:0000037} P31274 Homeobox protein Hox-C9 protein 20130413 {GO:0043565=IEA, GO:0003700=IEA, GO:0005634=IEA, GO:0048704=IEA, GO:0009952=IEA, GO:0006351=IEA} anterior/posterior pattern specification, embryonic skeletal system morphogenesis, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0191 HOXD1 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0048706=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q9GZZ0 Homeobox protein Hox-D1 protein 20130413 {GO:0043565=IEA, GO:0003700=IEA, GO:0048706=IEA, GO:0005634=IEA, GO:0006351=IEA} embryonic skeletal system development, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0191 HOXD10 UniProtKB UniProtKB {GO:0035137=GO_REF:0000019, GO:0008344=GO_REF:0000019, GO:0035136=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0021520=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0048704=GO_REF:0000019, GO:0009954=GO_REF:0000019, GO:0030326=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0050905=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0007519=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0048935=GO_REF:0000019} P28358 Homeobox protein Hox-D10 protein 20130413 {GO:0035137=IEA, GO:0008344=IEA, GO:0035136=IEA, GO:0003700=IEA, GO:0021520=IEA, GO:0005634=IEA, GO:0048704=IEA, GO:0009954=IEA, GO:0030326=IEA, GO:0009952=IEA, GO:0006351=IEA, GO:0050905=IEA, GO:0043565=IEA, GO:0007519=IEA, GO:0003682=IEA, GO:0045944=IEA, GO:0048935=IEA} adult locomotory behavior, anterior/posterior pattern specification, embryonic limb morphogenesis, embryonic skeletal system morphogenesis, forelimb morphogenesis, hindlimb morphogenesis, neuromuscular process, peripheral nervous system neuron development, positive regulation of transcription from RNA polymerase II promoter, proximal/distal pattern formation, skeletal muscle tissue development, spinal cord motor neuron cell fate specification, transcription, DNA-dependent nucleus chromatin binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0191 HOXD11 UniProtKB UniProtKB {GO:0001656=GO_REF:0000019, GO:0001658=GO_REF:0000024, GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000029, GO:0010720=GO_REF:0000019, GO:0009954=GO_REF:0000019, GO:0005634=GO_REF:0000029, GO:0009953=GO_REF:0000024, GO:0001759=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0048589=GO_REF:0000019, GO:0060272=GO_REF:0000019, GO:0060351=GO_REF:0000019, GO:0032332=GO_REF:0000019, GO:0042733=GO_REF:0000019} P31277 Homeobox protein Hox-D11 protein 20120509 {GO:0001656=IEA, GO:0001658=ISS, GO:0006355=NAS, GO:0003700=NAS, GO:0010720=IEA, GO:0009954=IEA, GO:0005634=NAS, GO:0009953=ISS, GO:0001759=IEA, GO:0009952=IEA, GO:0006351=IEA, GO:0043565=IEA, GO:0048589=IEA, GO:0060272=IEA, GO:0060351=IEA, GO:0032332=IEA, GO:0042733=IEA} anterior/posterior pattern specification, branching involved in ureteric bud morphogenesis, cartilage development involved in endochondral bone morphogenesis, developmental growth, dorsal/ventral pattern formation, embryonic digit morphogenesis, embryonic skeletal joint morphogenesis, metanephros development, organ induction, positive regulation of cell development, positive regulation of chondrocyte differentiation, proximal/distal pattern formation, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:P23813 HOXD12 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0007389=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0006355=GO_REF:0000029, GO:0001501=GO_REF:0000019, GO:0003700=GO_REF:0000029, GO:0007275=GO_REF:0000029, GO:0000228=GO_REF:0000029, GO:0003677=GO_REF:0000038, GO:0042733=GO_REF:0000019, GO:0006351=GO_REF:0000037} P35452 Homeobox protein Hox-D12 protein 20021104 {GO:0043565=IEA, GO:0007389=IEA, GO:0005667=IEA, GO:0006355=NAS, GO:0001501=IEA, GO:0003700=NAS, GO:0007275=NAS, GO:0000228=NAS, GO:0003677=IEA, GO:0042733=IEA, GO:0006351=IEA} embryonic digit morphogenesis, multicellular organismal development, pattern specification process, regulation of transcription, DNA-dependent, skeletal system development, transcription, DNA-dependent nuclear chromosome, transcription factor complex DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human HOXD13 PINC UniProtKB {GO:0006355=PMID:9207113, GO:0003700=GO_REF:0000019, GO:0006366=PMID:8614804, GO:0007275=PMID:9207113, GO:0005634=GO_REF:0000039, GO:0060571=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0003677=PMID:8614804, GO:0060687=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0030539=GO_REF:0000019, GO:0001501=GO_REF:0000019, GO:0048619=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0060602=GO_REF:0000019, GO:0042733=GO_REF:0000019, GO:0060527=GO_REF:0000019} P35453 Homeobox protein Hox-D13 protein 20030904 {GO:0006355=TAS, GO:0003700=IEA, GO:0006366=TAS, GO:0007275=TAS, GO:0005634=IEA, GO:0060571=IEA, GO:0009952=IEA, GO:0003677=TAS, GO:0060687=IEA, GO:0043565=IEA, GO:0030539=IEA, GO:0001501=IEA, GO:0048619=IEA, GO:0045944=IEA, GO:0042127=IEA, GO:0003682=IEA, GO:0060602=IEA, GO:0042733=IEA, GO:0060527=IEA} anterior/posterior pattern specification, branch elongation of an epithelium, embryonic digit morphogenesis, embryonic hindgut morphogenesis, male genitalia development, morphogenesis of an epithelial fold, multicellular organismal development, positive regulation of transcription from RNA polymerase II promoter, prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis, regulation of branching involved in prostate gland morphogenesis, regulation of cell proliferation, regulation of transcription, DNA-dependent, skeletal system development, transcription from RNA polymerase II promoter nucleus DNA binding, chromatin binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human HOXD3 UniProtKB UniProtKB {GO:0003700=GO_REF:0000002, GO:0051216=GO_REF:0000024, GO:0048704=GO_REF:0000024, GO:0005634=PMID:12836255, GO:0030878=GO_REF:0000024, GO:0009952=GO_REF:0000024, GO:0006351=PMID:12836255, GO:0043565=GO_REF:0000002, GO:0010628=PMID:12836255, GO:0021615=GO_REF:0000019, GO:0007219=PMID:12836255, GO:0007160=PMID:7742539, GO:0045666=GO_REF:0000024} P31249 Homeobox protein Hox-D3 protein 20110607 {GO:0003700=IEA, GO:0051216=ISS, GO:0048704=ISS, GO:0005634=IC, GO:0030878=ISS, GO:0009952=ISS, GO:0006351=IMP, GO:0043565=IEA, GO:0010628=IMP, GO:0021615=IEA, GO:0007219=IMP, GO:0007160=IDA, GO:0045666=ISS} Notch signaling pathway, anterior/posterior pattern specification, cartilage development, cell-matrix adhesion, embryonic skeletal system morphogenesis, glossopharyngeal nerve morphogenesis, positive regulation of gene expression, positive regulation of neuron differentiation, thyroid gland development, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human GO:0006351 HOXD4 UniProtKB UniProtKB {GO:0048863=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000029, GO:0005634=GO_REF:0000029, GO:0007275=PMID:2879245, GO:0048704=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0006351=GO_REF:0000037} P09016 Homeobox protein Hox-D4 protein 20021104 {GO:0048863=IEA, GO:0043565=IEA, GO:0006355=NAS, GO:0003700=NAS, GO:0005634=NAS, GO:0007275=NAS, GO:0048704=IEA, GO:0009952=IEA, GO:0006351=IEA} anterior/posterior pattern specification, embryonic skeletal system morphogenesis, multicellular organismal development, regulation of transcription, DNA-dependent, stem cell differentiation, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human HOXD8 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000029, GO:0048705=GO_REF:0000019, GO:0005634=PMID:2568311, GO:0007275=GO_REF:0000038, GO:0000122=GO_REF:0000019, GO:0008595=PMID:2568311, GO:0006351=GO_REF:0000037} P13378 Homeobox protein Hox-D8 protein 20010829 {GO:0043565=IEA, GO:0006355=NAS, GO:0003700=NAS, GO:0048705=IEA, GO:0005634=NAS, GO:0007275=IEA, GO:0000122=IEA, GO:0008595=NAS, GO:0006351=IEA} anterior/posterior axis specification, embryo, multicellular organismal development, negative regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, skeletal system morphogenesis, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human HOXD9 UniProtKB UniProtKB {GO:0035137=GO_REF:0000019, GO:0008344=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0009954=GO_REF:0000019, GO:0030879=GO_REF:0000019, GO:0048704=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0007519=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0048935=GO_REF:0000019, GO:0035115=GO_REF:0000019} P28356 Homeobox protein Hox-D9 protein 20130413 {GO:0035137=IEA, GO:0008344=IEA, GO:0003700=IEA, GO:0005634=IEA, GO:0009954=IEA, GO:0030879=IEA, GO:0048704=IEA, GO:0009952=IEA, GO:0006351=IEA, GO:0043565=IEA, GO:0007519=IEA, GO:0045944=IEA, GO:0048935=IEA, GO:0035115=IEA} adult locomotory behavior, anterior/posterior pattern specification, embryonic forelimb morphogenesis, embryonic skeletal system morphogenesis, hindlimb morphogenesis, mammary gland development, peripheral nervous system neuron development, positive regulation of transcription from RNA polymerase II promoter, proximal/distal pattern formation, skeletal muscle tissue development, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0191 HP InterPro UniProtKB {GO:0042542=PMID:19740759, GO:2000296=PMID:19740759, GO:0016209=GO_REF:0000037, GO:0051354=PMID:19740759, GO:0004252=GO_REF:0000002, GO:0005576=GO_REF:0000002, GO:0006952=PMID:7036344, GO:0006953=GO_REF:0000037, GO:0003824=GO_REF:0000002, GO:0005615=PMID:19433579, GO:0006879=GO_REF:0000029, GO:0031838=PMID:19740759, GO:0030492=GO_REF:0000002, GO:0071682=Reactome:REACT_160193, GO:0006508=GO_REF:0000002, GO:0010942=PMID:19740759, GO:0042742=GO_REF:0000037} Q0VAC5 HP protein protein 20130413 {GO:0042542=IDA, GO:2000296=IDA, GO:0016209=IEA, GO:0051354=IDA, GO:0004252=IEA, GO:0005576=IEA, GO:0006952=TAS, GO:0006953=IEA, GO:0003824=IEA, GO:0005615=IDA, GO:0006879=NAS, GO:0031838=IDA, GO:0030492=IEA, GO:0071682=TAS, GO:0006508=IEA, GO:0010942=IDA, GO:0042742=IEA} acute-phase response, cellular iron ion homeostasis, defense response, defense response to bacterium, negative regulation of hydrogen peroxide catabolic process, negative regulation of oxidoreductase activity, positive regulation of cell death, proteolysis, response to hydrogen peroxide endocytic vesicle lumen, extracellular region, extracellular space, haptoglobin-hemoglobin complex antioxidant activity, catalytic activity, hemoglobin binding, serine-type endopeptidase activity Human InterPro:IPR008292 HP1BP3 UniProtKB UniProtKB {GO:0006334=GO_REF:0000002, GO:0005634=GO_REF:0000038, GO:0000786=GO_REF:0000002, GO:0003677=GO_REF:0000038} Q5SWC8 Heterochromatin protein 1-binding protein 3 protein 20130413 {GO:0006334=IEA, GO:0005634=IEA, GO:0000786=IEA, GO:0003677=IEA} nucleosome assembly nucleosome, nucleus DNA binding Human UniProtKB-KW:KW-0539 HPCA UniProtKB UniProtKB {GO:0048839=GO_REF:0000019, GO:0005509=PMID:8387172, GO:0003779=PMID:11964161} P84074 Neuron-specific calcium-binding protein hippocalcin protein 20040715 {GO:0048839=IEA, GO:0005509=NAS, GO:0003779=IDA} inner ear development actin binding, calcium ion binding Human HPCAL1 InterPro UniProtKB {GO:0005509=GO_REF:0000002} P37235 Hippocalcin-like protein 1 protein 20130413 {GO:0005509=IEA} calcium ion binding Human InterPro:IPR001125|InterPro:IPR002048|InterPro:IPR011992 HPCAL4 LIFEdb UniProtKB {GO:0005622=GO_REF:0000054, GO:0005246=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0007417=PMID:10520747, GO:0008022=GO_REF:0000019} Q9UM19 Hippocalcin-like protein 4 protein 20100607 {GO:0005622=IDA, GO:0005246=IEA, GO:0019904=IEA, GO:0005509=IEA, GO:0007417=TAS, GO:0008022=IEA} central nervous system development intracellular calcium channel regulator activity, calcium ion binding, protein C-terminus binding, protein domain specific binding Human HPD Reactome UniProtKB {GO:0034641=Reactome:REACT_13, GO:0006559=Reactome:REACT_1786, GO:0003868=Reactome:REACT_1145, GO:0044281=Reactome:REACT_111217, GO:0006572=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_1145} P32754 4-hydroxyphenylpyruvate dioxygenase protein 20130213 {GO:0034641=TAS, GO:0006559=TAS, GO:0003868=EXP, GO:0044281=TAS, GO:0006572=ISS, GO:0046872=IEA, GO:0005829=TAS} L-phenylalanine catabolic process, cellular nitrogen compound metabolic process, small molecule metabolic process, tyrosine catabolic process cytosol 4-hydroxyphenylpyruvate dioxygenase activity, metal ion binding Human HPDL UniProtKB UniProtKB {GO:0003868=GO_REF:0000002, GO:0009072=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q96IR7 4-hydroxyphenylpyruvate dioxygenase-like protein protein 20130413 {GO:0003868=IEA, GO:0009072=IEA, GO:0046872=IEA} aromatic amino acid family metabolic process 4-hydroxyphenylpyruvate dioxygenase activity, metal ion binding Human UniProtKB-KW:KW-0479 HPGD HPA UniProtKB {GO:0019371=Reactome:REACT_150149, GO:0019369=Reactome:REACT_147851, GO:0007565=PMID:15531523, GO:0006693=PMID:16828555, GO:0007567=PMID:15531523, GO:0019372=PMID:15581601, GO:0005730=GO_REF:0000052, GO:0070403=PMID:16828555, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0003824=PMID:2025296, GO:0045786=PMID:15574495, GO:0004957=PMID:10198228, GO:0042803=PMID:2025296, GO:0005829=Reactome:REACT_150285, GO:0005737=GO_REF:0000052, GO:0051287=PMID:10198228, GO:0070493=GO_REF:0000024, GO:0016491=GO_REF:0000002, GO:0007179=PMID:15574495, GO:2001300=Reactome:REACT_150320, GO:0097070=GO_REF:0000024, GO:0030728=GO_REF:0000024, GO:0016404=Reactome:REACT_150285} P15428 "15-hydroxyprostaglandin dehydrogenase ""NAD(+)""" protein 20101115 {GO:0019371=TAS, GO:0019369=TAS, GO:0007565=IDA, GO:0006693=IDA, GO:0007567=IDA, GO:0019372=TAS, GO:0005730=IDA, GO:0070403=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0003824=IDA, GO:0045786=IDA, GO:0004957=IDA, GO:0042803=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0051287=IDA, GO:0070493=ISS, GO:0016491=IEA, GO:0007179=IDA, GO:2001300=TAS, GO:0097070=ISS, GO:0030728=ISS, GO:0016404=TAS} arachidonic acid metabolic process, cyclooxygenase pathway, ductus arteriosus closure, female pregnancy, lipoxin metabolic process, lipoxygenase pathway, negative regulation of cell cycle, ovulation, parturition, prostaglandin metabolic process, small molecule metabolic process, thrombin receptor signaling pathway, transforming growth factor beta receptor signaling pathway cytoplasm, cytosol, nucleolus, nucleus 15-hydroxyprostaglandin dehydrogenase (NAD+) activity, NAD binding, NAD+ binding, catalytic activity, oxidoreductase activity, prostaglandin E receptor activity, protein homodimerization activity Human HPGDS HPA UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0019371=Reactome:REACT_150149, GO:0006693=PMID:12627223, GO:0000287=PMID:12627223, GO:0005509=PMID:12627223, GO:0005730=GO_REF:0000052, GO:0004667=Reactome:REACT_150171, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0004364=GO_REF:0000003, GO:0042803=PMID:12627223, GO:0005829=Reactome:REACT_150171, GO:0007165=PMID:9353279, GO:0005737=GO_REF:0000052, GO:0007626=PMID:10781097} O60760 Hematopoietic prostaglandin D synthase protein 20100326 {GO:0019369=TAS, GO:0019371=TAS, GO:0006693=IDA, GO:0000287=IDA, GO:0005509=IDA, GO:0005730=IDA, GO:0004667=EXP, GO:0005634=IDA, GO:0044281=TAS, GO:0004364=IEA, GO:0042803=IPI, GO:0005829=TAS, GO:0007165=NAS, GO:0005737=IDA, GO:0007626=TAS} arachidonic acid metabolic process, cyclooxygenase pathway, locomotory behavior, prostaglandin metabolic process, signal transduction, small molecule metabolic process cytoplasm, cytosol, nucleolus, nucleus calcium ion binding, glutathione transferase activity, magnesium ion binding, prostaglandin-D synthase activity, protein homodimerization activity Human HPN HPA UniProtKB {GO:0005515=PMID:19911255, GO:0060429=GO_REF:0000019, GO:0097066=GO_REF:0000024, GO:0004252=PMID:16908524, GO:0030307=PMID:8346233, GO:0008360=PMID:8346233, GO:0050680=PMID:19843851, GO:0010719=PMID:19843851, GO:0005737=GO_REF:0000052, GO:0005911=GO_REF:0000024, GO:0043025=GO_REF:0000024, GO:0006508=PMID:19843851, GO:0090103=GO_REF:0000024, GO:2000611=GO_REF:0000024, GO:0071805=GO_REF:0000024, GO:0070008=GO_REF:0000002, GO:0034769=PMID:16908524, GO:0005044=GO_REF:0000002, GO:0009986=PMID:16908524, GO:0097195=GO_REF:0000024, GO:0010628=GO_REF:0000024, GO:0016020=GO_REF:0000002, GO:0005887=PMID:1885621, GO:0050910=GO_REF:0000024, GO:0005789=PMID:17918732, GO:0008233=PMID:16908524, GO:0016021=PMID:19843851, GO:0015269=GO_REF:0000024} P05981 Serine protease hepsin protein 20080205 {GO:0005515=IPI, GO:0060429=IEA, GO:0097066=ISS, GO:0004252=IDA, GO:0030307=IMP, GO:0008360=IMP, GO:0050680=IDA, GO:0010719=IDA, GO:0005737=IDA, GO:0005911=ISS, GO:0043025=ISS, GO:0006508=IDA, GO:0090103=ISS, GO:2000611=ISS, GO:0071805=ISS, GO:0070008=IEA, GO:0034769=IDA, GO:0005044=IEA, GO:0009986=IDA, GO:0097195=ISS, GO:0010628=ISS, GO:0016020=IEA, GO:0005887=IDA, GO:0050910=ISS, GO:0005789=IDA, GO:0008233=IDA, GO:0016021=IDA, GO:0015269=ISS} basement membrane disassembly, cochlea morphogenesis, detection of mechanical stimulus involved in sensory perception of sound, epithelium development, negative regulation of epithelial cell proliferation, negative regulation of epithelial to mesenchymal transition, pilomotor reflex, positive regulation of cell growth, positive regulation of gene expression, positive regulation of thyroid hormone generation, potassium ion transmembrane transport, proteolysis, regulation of cell shape, response to thyroid hormone stimulus cell surface, cell-cell junction, cytoplasm, endoplasmic reticulum membrane, integral to membrane, integral to plasma membrane, membrane, neuronal cell body calcium-activated potassium channel activity, peptidase activity, protein binding, scavenger receptor activity, serine-type endopeptidase activity, serine-type exopeptidase activity Human HPR BHF-UCL UniProtKB {GO:0030492=PMID:2987228, GO:0034366=PMID:16682745, GO:0005576=Reactome:REACT_160200, GO:0003824=GO_REF:0000002} P00739 Haptoglobin-related protein protein 20090507 {GO:0030492=NAS, GO:0034366=IDA, GO:0005576=TAS, GO:0003824=IEA} extracellular region, spherical high-density lipoprotein particle catalytic activity, hemoglobin binding Human HPRT1 HPA UniProtKB {GO:0005515=PMID:19060904, GO:0046040=PMID:19527031, GO:0044281=Reactome:REACT_111217, GO:0042803=PMID:8044844, GO:0005829=Reactome:REACT_1444, GO:0006178=PMID:19527031, GO:0045964=PMID:8643611, GO:0005737=GO_REF:0000052, GO:0042417=GO_REF:0000019, GO:0000166=GO_REF:0000037, GO:0051289=PMID:15990111, GO:0032264=GO_REF:0000033, GO:0019835=GO_REF:0000019, GO:0032263=GO_REF:0000033, GO:0043101=Reactome:REACT_1923, GO:0046038=PMID:19527031, GO:0007610=PMID:16138897, GO:0043103=PMID:19527031, GO:0007625=GO_REF:0000019, GO:0021895=GO_REF:0000019, GO:0000287=PMID:10360366, GO:0004422=Reactome:REACT_1444, GO:0052657=PMID:19527031, GO:0021954=GO_REF:0000019, GO:0055086=Reactome:REACT_1698, GO:0021756=GO_REF:0000019, GO:0006166=PMID:9824441, GO:0048813=GO_REF:0000019, GO:0001975=GO_REF:0000019, GO:0006168=GO_REF:0000033, GO:0006144=Reactome:REACT_522, GO:0046100=PMID:9824441, GO:0046651=GO_REF:0000019, GO:0006164=PMID:9824441} P00492 Hypoxanthine-guanine phosphoribosyltransferase protein 20080205 {GO:0005515=IPI, GO:0046040=IDA, GO:0044281=TAS, GO:0042803=IPI, GO:0005829=TAS, GO:0006178=IDA, GO:0045964=IMP, GO:0005737=IDA, GO:0042417=IEA, GO:0000166=IEA, GO:0051289=IPI, GO:0032264=IBA, GO:0019835=IEA, GO:0032263=IBA, GO:0043101=TAS, GO:0046038=IDA, GO:0007610=IMP, GO:0043103=IDA, GO:0007625=IEA, GO:0021895=IEA, GO:0000287=IDA, GO:0004422=EXP, GO:0052657=IDA, GO:0021954=IEA, GO:0055086=TAS, GO:0021756=IEA, GO:0006166=IMP, GO:0048813=IEA, GO:0001975=IEA, GO:0006168=IBA, GO:0006144=TAS, GO:0046100=IMP, GO:0046651=IEA, GO:0006164=IMP} GMP catabolic process, GMP salvage, IMP metabolic process, IMP salvage, adenine salvage, behavior, central nervous system neuron development, cerebral cortex neuron differentiation, cytolysis, dendrite morphogenesis, dopamine metabolic process, grooming behavior, guanine salvage, hypoxanthine metabolic process, hypoxanthine salvage, lymphocyte proliferation, nucleobase-containing small molecule metabolic process, positive regulation of dopamine metabolic process, protein homotetramerization, purine nucleobase metabolic process, purine nucleotide biosynthetic process, purine ribonucleoside salvage, purine-containing compound salvage, response to amphetamine, small molecule metabolic process, striatum development cytoplasm, cytosol guanine phosphoribosyltransferase activity, hypoxanthine phosphoribosyltransferase activity, magnesium ion binding, nucleotide binding, protein binding, protein homodimerization activity Human HPS1 PINC UniProtKB {GO:0060041=GO_REF:0000019, GO:0030318=GO_REF:0000019, GO:0005764=PMID:10625677, GO:0032816=GO_REF:0000019, GO:0005737=PMID:10625677, GO:0007596=GO_REF:0000019, GO:0005887=PMID:8896559, GO:0033299=GO_REF:0000019, GO:0048069=GO_REF:0000019, GO:0046983=PMID:12663659, GO:0016023=PMID:11836498, GO:0007601=GO_REF:0000037, GO:0007040=PMID:10625677} Q92902 Hermansky-Pudlak syndrome 1 protein protein 20030904 {GO:0060041=IEA, GO:0030318=IEA, GO:0005764=TAS, GO:0032816=IEA, GO:0005737=TAS, GO:0007596=IEA, GO:0005887=TAS, GO:0033299=IEA, GO:0048069=IEA, GO:0046983=IPI, GO:0016023=IDA, GO:0007601=IEA, GO:0007040=TAS} blood coagulation, eye pigmentation, lysosome organization, melanocyte differentiation, positive regulation of natural killer cell activation, retina development in camera-type eye, secretion of lysosomal enzymes, visual perception cytoplasm, cytoplasmic membrane-bounded vesicle, integral to plasma membrane, lysosome protein dimerization activity Human HPS3 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0006996=GO_REF:0000019, GO:0043473=GO_REF:0000019} Q969F9 Hermansky-Pudlak syndrome 3 protein protein 20130413 {GO:0005737=IEA, GO:0006996=IEA, GO:0043473=IEA} organelle organization, pigmentation cytoplasm Human UniProtKB-SubCell:SL-0086 HPS4 UniProtKB UniProtKB {GO:0042470=PMID:12663659, GO:0042827=PMID:12756248, GO:0050821=PMID:12663659, GO:0030318=GO_REF:0000019, GO:0006605=PMID:12663659, GO:0005764=PMID:12663659, GO:0042803=PMID:12663659, GO:0007599=PMID:11836498, GO:0005737=PMID:12756248, GO:0016020=PMID:12756248, GO:0007596=GO_REF:0000019, GO:0046983=PMID:12663659, GO:0007040=PMID:12663659, GO:0048075=PMID:11836498} Q9NQG7 Hermansky-Pudlak syndrome 4 protein protein 20030807 {GO:0042470=IDA, GO:0042827=IDA, GO:0050821=IPI, GO:0030318=IEA, GO:0006605=IDA, GO:0005764=IDA, GO:0042803=IPI, GO:0007599=TAS, GO:0005737=IDA, GO:0016020=IDA, GO:0007596=IEA, GO:0046983=IPI, GO:0007040=IDA, GO:0048075=TAS} blood coagulation, hemostasis, lysosome organization, melanocyte differentiation, positive regulation of eye pigmentation, protein stabilization, protein targeting cytoplasm, lysosome, melanosome, membrane, platelet dense granule protein dimerization activity, protein homodimerization activity Human HPS5 UniProtKB UniProtKB {GO:0006996=GO_REF:0000019, GO:0007596=GO_REF:0000019, GO:0043473=GO_REF:0000019, GO:0005829=GO_REF:0000039} Q9UPZ3 Hermansky-Pudlak syndrome 5 protein protein 20130413 {GO:0006996=IEA, GO:0007596=IEA, GO:0043473=IEA, GO:0005829=IEA} blood coagulation, organelle organization, pigmentation cytosol Human UniProtKB-SubCell:SL-0091 HPS6 UniProtKB UniProtKB {GO:0006996=GO_REF:0000019, GO:0007596=GO_REF:0000019, GO:0005783=GO_REF:0000037, GO:0031901=GO_REF:0000039, GO:0030318=GO_REF:0000019, GO:0005829=GO_REF:0000039} Q86YV9 Hermansky-Pudlak syndrome 6 protein protein 20130413 {GO:0006996=IEA, GO:0007596=IEA, GO:0005783=IEA, GO:0031901=IEA, GO:0030318=IEA, GO:0005829=IEA} blood coagulation, melanocyte differentiation, organelle organization cytosol, early endosome membrane, endoplasmic reticulum Human UniProtKB-SubCell:SL-0093 HPSE Reactome UniProtKB {GO:0005515=PMID:20561914, GO:0051897=PMID:15044433, GO:0030305=Reactome:REACT_121335, GO:0005634=PMID:20309870, GO:0044281=Reactome:REACT_111217, GO:0005765=GO_REF:0000039, GO:0005764=PMID:15126626, GO:0061042=GO_REF:0000019, GO:0016798=GO_REF:0000002, GO:0046983=PMID:12927802, GO:0030200=PMID:12213822, GO:0033690=PMID:20309870, GO:0030203=Reactome:REACT_121315, GO:0043202=Reactome:REACT_121335, GO:0004566=PMID:10395325, GO:0005975=Reactome:REACT_474, GO:0006027=Reactome:REACT_120752, GO:0005576=GO_REF:0000039, GO:0006029=PMID:10446189, GO:0010575=PMID:16452201, GO:0051798=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0007160=PMID:12773484, GO:0030194=PMID:20634491, GO:0045121=GO_REF:0000019, GO:0045545=PMID:15292202, GO:0051797=PMID:18557927} Q9Y251 Heparanase protein 20111014 {GO:0005515=IPI, GO:0051897=IDA, GO:0030305=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0005765=IEA, GO:0005764=IDA, GO:0061042=IEA, GO:0016798=IEA, GO:0046983=IDA, GO:0030200=IDA, GO:0033690=IDA, GO:0030203=TAS, GO:0043202=TAS, GO:0004566=TAS, GO:0005975=TAS, GO:0006027=TAS, GO:0005576=IEA, GO:0006029=TAS, GO:0010575=IDA, GO:0051798=IEA, GO:0016020=IEA, GO:0007160=IDA, GO:0030194=IDA, GO:0045121=IEA, GO:0045545=IDA, GO:0051797=IDA} carbohydrate metabolic process, cell-matrix adhesion, glycosaminoglycan catabolic process, glycosaminoglycan metabolic process, heparan sulfate proteoglycan catabolic process, positive regulation of blood coagulation, positive regulation of hair follicle development, positive regulation of osteoblast proliferation, positive regulation of protein kinase B signaling cascade, positive regulation vascular endothelial growth factor production, proteoglycan metabolic process, regulation of hair follicle development, small molecule metabolic process, vascular wound healing extracellular region, lysosomal lumen, lysosomal membrane, lysosome, membrane, membrane raft, nucleus beta-glucuronidase activity, heparanase activity, hydrolase activity, acting on glycosyl bonds, protein binding, protein dimerization activity, syndecan binding Human HPX Reactome UniProtKB {GO:0005515=PMID:20610401, GO:0015886=PMID:3855550, GO:0020027=GO_REF:0000019, GO:0015232=PMID:3855550, GO:0042511=GO_REF:0000019, GO:0005576=Reactome:REACT_160297, GO:0005615=PMID:19433579, GO:0046872=GO_REF:0000037, GO:0006879=PMID:3855550, GO:0060335=GO_REF:0000019, GO:0002925=GO_REF:0000019, GO:0002639=GO_REF:0000019, GO:0071682=Reactome:REACT_160232, GO:0019048=GO_REF:0000037, GO:0042168=GO_REF:0000019} P02790 Hemopexin protein 20121007 {GO:0005515=IPI, GO:0015886=TAS, GO:0020027=IEA, GO:0015232=TAS, GO:0042511=IEA, GO:0005576=TAS, GO:0005615=IDA, GO:0046872=IEA, GO:0006879=TAS, GO:0060335=IEA, GO:0002925=IEA, GO:0002639=IEA, GO:0071682=TAS, GO:0019048=IEA, GO:0042168=IEA} cellular iron ion homeostasis, heme metabolic process, heme transport, hemoglobin metabolic process, positive regulation of humoral immune response mediated by circulating immunoglobulin, positive regulation of immunoglobulin production, positive regulation of interferon-gamma-mediated signaling pathway, positive regulation of tyrosine phosphorylation of Stat1 protein, virus-host interaction endocytic vesicle lumen, extracellular region, extracellular space heme transporter activity, metal ion binding, protein binding Human HR UniProtKB UniProtKB {GO:0016604=GO_REF:0000019, GO:0006355=PMID:9445480, GO:0003700=PMID:9445480, GO:0003714=GO_REF:0000019, GO:0005634=PMID:9445480, GO:0003677=PMID:9445480, GO:0045892=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037} O43593 Protein hairless protein 20010912 {GO:0016604=IEA, GO:0006355=NAS, GO:0003700=NAS, GO:0003714=IEA, GO:0005634=NAS, GO:0003677=NAS, GO:0045892=IEA, GO:0046872=IEA, GO:0006351=IEA} negative regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent nuclear body, nucleus DNA binding, metal ion binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human HRAS BHF-UCL UniProtKB {GO:0005515=PMID:22169110, GO:0034259=PMID:23027131, GO:0046330=PMID:22065586, GO:2000251=PMID:23027131, GO:0050900=Reactome:REACT_12051, GO:0032855=PMID:23027131, GO:0043524=GO_REF:0000019, GO:1900029=PMID:23027131, GO:0006935=PMID:10848592, GO:0007173=Reactome:REACT_9417, GO:0000165=Reactome:REACT_634, GO:0007411=Reactome:REACT_18266, GO:0048169=GO_REF:0000019, GO:0009887=PMID:10848592, GO:0070374=PMID:22065586, GO:0050679=PMID:20154697, GO:0030335=PMID:23027131, GO:0005794=PMID:14500341, GO:0045740=PMID:9765203, GO:0006897=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0008542=GO_REF:0000019, GO:0032228=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0035176=GO_REF:0000019, GO:0051146=GO_REF:0000019, GO:0090398=PMID:9054499, GO:0008286=Reactome:REACT_498, GO:2000630=PMID:23027131, GO:0007093=PMID:9054499, GO:0048471=GO_REF:0000039, GO:0008284=PMID:9765203, GO:0008285=PMID:9054499, GO:0030036=GO_REF:0000019, GO:0005886=Reactome:REACT_147697, GO:0035022=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:0007264=Reactome:REACT_12077, GO:0090303=PMID:23027131, GO:0003924=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0005634=GO_REF:0000039, GO:0007265=PMID:23027131, GO:0051291=GO_REF:0000019, GO:0005829=Reactome:REACT_20612, GO:0005737=PMID:10842192, GO:0000186=Reactome:REACT_12005, GO:0043406=PMID:23027131, GO:0045944=PMID:23027131, GO:0007050=PMID:9054499, GO:0048011=Reactome:REACT_11061, GO:0006917=GO_REF:0000019, GO:0005525=PMID:17260967, GO:0008022=PMID:9219684, GO:0097193=GO_REF:0000019, GO:0007165=PMID:8607982, GO:0000139=GO_REF:0000039, GO:0007596=Reactome:REACT_604, GO:0010629=PMID:23027131, GO:0001934=PMID:22065586, GO:0043410=PMID:9765203, GO:0007166=PMID:9020890} P01112 GTPase HRas protein 20121130 {GO:0005515=IPI, GO:0034259=IDA, GO:0046330=IDA, GO:2000251=IDA, GO:0050900=TAS, GO:0032855=IDA, GO:0043524=IEA, GO:1900029=IDA, GO:0006935=TAS, GO:0007173=TAS, GO:0000165=TAS, GO:0007411=TAS, GO:0048169=IEA, GO:0009887=TAS, GO:0070374=IDA, GO:0050679=IMP, GO:0030335=IDA, GO:0005794=IDA, GO:0045740=IDA, GO:0006897=IEA, GO:0008543=TAS, GO:0008542=IEA, GO:0032228=IEA, GO:0045087=TAS, GO:0035176=IEA, GO:0051146=IEA, GO:0090398=IDA, GO:0008286=TAS, GO:2000630=IDA, GO:0007093=IDA, GO:0048471=IEA, GO:0008284=IDA, GO:0008285=IDA, GO:0030036=IEA, GO:0005886=TAS, GO:0035022=IEA, GO:0008283=IEA, GO:0007264=TAS, GO:0090303=IDA, GO:0003924=IEA, GO:0007268=TAS, GO:0005634=IEA, GO:0007265=IDA, GO:0051291=IEA, GO:0005829=TAS, GO:0005737=TAS, GO:0000186=TAS, GO:0043406=IDA, GO:0045944=IDA, GO:0007050=IDA, GO:0048011=TAS, GO:0006917=IEA, GO:0005525=IDA, GO:0008022=IPI, GO:0097193=IEA, GO:0007165=NAS, GO:0000139=IEA, GO:0007596=TAS, GO:0010629=IDA, GO:0001934=IDA, GO:0043410=IDA, GO:0007166=TAS} MAPK cascade, Ras protein signal transduction, actin cytoskeleton organization, activation of MAPKK activity, axon guidance, blood coagulation, cell cycle arrest, cell proliferation, cell surface receptor signaling pathway, cellular senescence, chemotaxis, endocytosis, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, induction of apoptosis, innate immune response, insulin receptor signaling pathway, intrinsic apoptotic signaling pathway, leukocyte migration, mitotic cell cycle checkpoint, negative regulation of Rho GTPase activity, negative regulation of cell proliferation, negative regulation of gene expression, negative regulation of neuron apoptotic process, neurotrophin TRK receptor signaling pathway, organ morphogenesis, positive regulation of DNA replication, positive regulation of ERK1 and ERK2 cascade, positive regulation of JNK cascade, positive regulation of MAP kinase activity, positive regulation of MAPK cascade, positive regulation of Rac GTPase activity, positive regulation of Rac protein signal transduction, positive regulation of actin cytoskeleton reorganization, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of epithelial cell proliferation, positive regulation of miRNA metabolic process, positive regulation of protein phosphorylation, positive regulation of ruffle assembly, positive regulation of transcription from RNA polymerase II promoter, positive regulation of wound healing, protein heterooligomerization, regulation of long-term neuronal synaptic plasticity, regulation of synaptic transmission, GABAergic, signal transduction, small GTPase mediated signal transduction, social behavior, striated muscle cell differentiation, synaptic transmission, visual learning Golgi apparatus, Golgi membrane, cytoplasm, cytosol, nucleus, perinuclear region of cytoplasm, plasma membrane GTP binding, GTPase activity, protein C-terminus binding, protein binding Human HRASLS ENSEMBL UniProtKB {GO:0016042=GO_REF:0000037, GO:0005641=GO_REF:0000019, GO:0046485=GO_REF:0000019, GO:0007031=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0004620=GO_REF:0000019, GO:0016740=GO_REF:0000037, GO:0005777=GO_REF:0000019} Q9HDD0 Phospholipid-metabolizing enzyme A-C1 protein 20130413 {GO:0016042=IEA, GO:0005641=IEA, GO:0046485=IEA, GO:0007031=IEA, GO:0016021=IEA, GO:0004620=IEA, GO:0016740=IEA, GO:0005777=IEA} ether lipid metabolic process, lipid catabolic process, peroxisome organization integral to membrane, nuclear envelope lumen, peroxisome phospholipase activity, transferase activity Human Ensembl:ENSMUSP00000087257 HRASLS5 UniProtKB UniProtKB {GO:0016746=GO_REF:0000037} Q96KN8 Ca(2+)-independent N-acyltransferase protein 20130413 {GO:0016746=IEA} transferase activity, transferring acyl groups Human UniProtKB-KW:KW-0012 HRC BHF-UCL UniProtKB {GO:0005515=PMID:17526652, GO:0006936=PMID:2037293, GO:0005509=PMID:2037293, GO:0033018=PMID:11504710, GO:0010881=PMID:17526652, GO:0033017=GO_REF:0000019, GO:0055074=GO_REF:0000019} P23327 Sarcoplasmic reticulum histidine-rich calcium-binding protein protein 20130218 {GO:0005515=IPI, GO:0006936=TAS, GO:0005509=TAS, GO:0033018=TAS, GO:0010881=TAS, GO:0033017=IEA, GO:0055074=IEA} calcium ion homeostasis, muscle contraction, regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion sarcoplasmic reticulum lumen, sarcoplasmic reticulum membrane calcium ion binding, protein binding Human HRG IntAct UniProtKB {GO:0010468=PMID:21215706, GO:0005515=PMID:21988832, GO:0033629=PMID:16489009, GO:0030308=PMID:21215706, GO:0043498=PMID:16436387, GO:0008285=PMID:14744774, GO:0004869=GO_REF:0000002, GO:0005886=Reactome:REACT_2235, GO:0004867=GO_REF:0000019, GO:0050730=PMID:16489009, GO:0010543=GO_REF:0000024, GO:0050832=PMID:18797515, GO:0051894=PMID:14744774, GO:0046872=PMID:678554, GO:0010593=PMID:16489009, GO:0006935=GO_REF:0000037, GO:0019865=PMID:10514432, GO:0032956=PMID:16489009, GO:0031093=Reactome:REACT_21351, GO:0008201=PMID:16436387, GO:0043065=PMID:14744774, GO:0051918=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_21351, GO:0043395=PMID:16436387, GO:0001525=GO_REF:0000037, GO:1900747=PMID:16489009, GO:0007162=PMID:14744774, GO:0002839=PMID:21215706, GO:0030193=PMID:6740558, GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0016525=PMID:14744774, GO:0043254=PMID:16489009, GO:0008270=PMID:16436387, GO:2001027=PMID:14744774, GO:0042730=Reactome:REACT_641, GO:0043537=GO_REF:0000024, GO:2000504=PMID:21215706, GO:0020037=PMID:678554} P04196 Histidine-rich glycoprotein protein 20130415 {GO:0010468=IDA, GO:0005515=IPI, GO:0033629=IDA, GO:0030308=IDA, GO:0043498=IDA, GO:0008285=IDA, GO:0004869=IEA, GO:0005886=TAS, GO:0004867=IEA, GO:0050730=IDA, GO:0010543=ISS, GO:0050832=IDA, GO:0051894=IDA, GO:0046872=IDA, GO:0010593=IDA, GO:0006935=IEA, GO:0019865=IDA, GO:0032956=IDA, GO:0031093=TAS, GO:0008201=IDA, GO:0043065=IDA, GO:0051918=IEA, GO:0030168=TAS, GO:0005576=TAS, GO:0043395=IDA, GO:0001525=IEA, GO:1900747=IDA, GO:0007162=IDA, GO:0002839=IDA, GO:0030193=IDA, GO:0007596=TAS, GO:0002576=TAS, GO:0016525=IDA, GO:0043254=IDA, GO:0008270=IDA, GO:2001027=IDA, GO:0042730=TAS, GO:0043537=ISS, GO:2000504=IDA, GO:0020037=IDA} angiogenesis, blood coagulation, chemotaxis, defense response to fungus, fibrinolysis, negative regulation of angiogenesis, negative regulation of blood vessel endothelial cell migration, negative regulation of cell adhesion, negative regulation of cell adhesion mediated by integrin, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of endothelial cell chemotaxis, negative regulation of fibrinolysis, negative regulation of lamellipodium assembly, negative regulation of vascular endothelial growth factor signaling pathway, platelet activation, platelet degranulation, positive regulation of apoptotic process, positive regulation of blood vessel remodeling, positive regulation of focal adhesion assembly, positive regulation of immune response to tumor cell, regulation of actin cytoskeleton organization, regulation of blood coagulation, regulation of gene expression, regulation of peptidyl-tyrosine phosphorylation, regulation of platelet activation, regulation of protein complex assembly extracellular region, plasma membrane, platelet alpha granule lumen cell surface binding, cysteine-type endopeptidase inhibitor activity, heme binding, heparan sulfate proteoglycan binding, heparin binding, immunoglobulin binding, metal ion binding, protein binding, serine-type endopeptidase inhibitor activity, zinc ion binding Human UniProtKB:Q96PM5 HRH1 HPA UniProtKB {GO:0005886=GO_REF:0000052, GO:0004930=PMID:7925364, GO:0048016=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0050804=GO_REF:0000002, GO:0007200=PMID:8280179, GO:0005634=GO_REF:0000052, GO:0004969=GO_REF:0000024, GO:0007204=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0006954=PMID:10818238, GO:0045907=GO_REF:0000002, GO:0007186=PMID:7925364, GO:0005887=GO_REF:0000024, GO:0043114=GO_REF:0000002, GO:0048245=GO_REF:0000002, GO:0032962=GO_REF:0000024, GO:0030814=GO_REF:0000002, GO:0071420=GO_REF:0000024} P35367 Histamine H1 receptor protein 20101115 {GO:0005886=IDA, GO:0004930=TAS, GO:0048016=ISS, GO:0005730=IDA, GO:0050804=IEA, GO:0007200=TAS, GO:0005634=IDA, GO:0004969=ISS, GO:0007204=IEA, GO:0005737=IDA, GO:0006954=TAS, GO:0045907=IEA, GO:0007186=TAS, GO:0005887=ISS, GO:0043114=IEA, GO:0048245=IEA, GO:0032962=ISS, GO:0030814=IEA, GO:0071420=ISS} G-protein coupled receptor signaling pathway, cellular response to histamine, elevation of cytosolic calcium ion concentration, eosinophil chemotaxis, inflammatory response, inositol phosphate-mediated signaling, phospholipase C-activating G-protein coupled receptor signaling pathway, positive regulation of inositol trisphosphate biosynthetic process, positive regulation of vasoconstriction, regulation of cAMP metabolic process, regulation of synaptic transmission, regulation of vascular permeability cytoplasm, integral to plasma membrane, nucleolus, nucleus, plasma membrane G-protein coupled receptor activity, histamine receptor activity Human HRH2 Reactome UniProtKB {GO:0006955=PMID:9725260, GO:0005886=Reactome:REACT_22268, GO:0045907=GO_REF:0000002, GO:0007187=PMID:9725260, GO:0005887=PMID:1714721, GO:0050804=GO_REF:0000002, GO:0030814=GO_REF:0000002, GO:0004969=GO_REF:0000002, GO:0001696=GO_REF:0000002} P25021 Histamine H2 receptor protein 20100217 {GO:0006955=TAS, GO:0005886=TAS, GO:0045907=IEA, GO:0007187=TAS, GO:0005887=TAS, GO:0050804=IEA, GO:0030814=IEA, GO:0004969=IEA, GO:0001696=IEA} G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, gastric acid secretion, immune response, positive regulation of vasoconstriction, regulation of cAMP metabolic process, regulation of synaptic transmission integral to plasma membrane, plasma membrane histamine receptor activity Human HRH3 Reactome UniProtKB {GO:0005886=Reactome:REACT_22289, GO:0007187=PMID:10347254, GO:0005887=PMID:10347254, GO:0030814=GO_REF:0000002, GO:0004969=GO_REF:0000002, GO:0007204=GO_REF:0000002, GO:0007269=PMID:10347254} Q9Y5N1 Histamine H3 receptor protein 20100217 {GO:0005886=TAS, GO:0007187=TAS, GO:0005887=TAS, GO:0030814=IEA, GO:0004969=IEA, GO:0007204=IEA, GO:0007269=TAS} G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, elevation of cytosolic calcium ion concentration, neurotransmitter secretion, regulation of cAMP metabolic process integral to plasma membrane, plasma membrane histamine receptor activity Human HRH4 Reactome UniProtKB {GO:0008150=GO_REF:0000015, GO:0006954=GO_REF:0000002, GO:0005886=Reactome:REACT_22289, GO:0043408=GO_REF:0000002, GO:0016021=GO_REF:0000029, GO:0004969=PMID:11118334, GO:0007204=GO_REF:0000002} Q9H3N8 Histamine H4 receptor protein 20100217 {GO:0008150=ND, GO:0006954=IEA, GO:0005886=TAS, GO:0043408=IEA, GO:0016021=NAS, GO:0004969=NAS, GO:0007204=IEA} biological_process, elevation of cytosolic calcium ion concentration, inflammatory response, regulation of MAPK cascade integral to membrane, plasma membrane histamine receptor activity Human HRK BHF-UCL UniProtKB {GO:0032464=PMID:21041309, GO:0005515=PMID:15694340, GO:0005739=PMID:15031724, GO:0043065=PMID:15031724, GO:0090200=PMID:21041309, GO:0006915=GO_REF:0000037, GO:0006917=PMID:9130713, GO:0016021=GO_REF:0000037} O00198 Activator of apoptosis harakiri protein 20110317 {GO:0032464=IDA, GO:0005515=IPI, GO:0005739=IDA, GO:0043065=IMP, GO:0090200=IDA, GO:0006915=IEA, GO:0006917=TAS, GO:0016021=IEA} apoptotic process, induction of apoptosis, positive regulation of apoptotic process, positive regulation of protein homooligomerization, positive regulation of release of cytochrome c from mitochondria integral to membrane, mitochondrion protein binding Human HRNR ENSEMBL UniProtKB {GO:0005509=GO_REF:0000002, GO:0031424=GO_REF:0000037, GO:0001533=GO_REF:0000019} Q86YZ3 Hornerin protein 20130413 {GO:0005509=IEA, GO:0031424=IEA, GO:0001533=IEA} keratinization cornified envelope calcium ion binding Human Ensembl:ENSMUSP00000088369 HRSP12 HPA UniProtKB {GO:0005739=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0004519=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0019239=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0006449=PMID:8530410} P52758 Ribonuclease UK114 protein 20101115 {GO:0005739=IEA, GO:0005737=IDA, GO:0004519=IEA, GO:0005730=IDA, GO:0019239=IEA, GO:0005634=IDA, GO:0006449=TAS} regulation of translational termination cytoplasm, mitochondrion, nucleolus, nucleus deaminase activity, endonuclease activity Human HS1BP3 InterPro UniProtKB {GO:0007154=GO_REF:0000002, GO:0035091=GO_REF:0000002} Q53T59 HCLS1-binding protein 3 protein 20130413 {GO:0007154=IEA, GO:0035091=IEA} cell communication phosphatidylinositol binding Human InterPro:IPR001683 HS3ST1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005975=Reactome:REACT_474, GO:0005796=Reactome:REACT_120741, GO:0008146=PMID:9988767, GO:0044281=Reactome:REACT_111217, GO:0016021=PMID:9988767, GO:0008467=GO_REF:0000003, GO:0030203=Reactome:REACT_121315, GO:0006024=Reactome:REACT_121248} O14792 Heparan sulfate glucosamine 3-O-sulfotransferase 1 protein 20080818 {GO:0005737=IDA, GO:0005975=TAS, GO:0005796=TAS, GO:0008146=TAS, GO:0044281=TAS, GO:0016021=TAS, GO:0008467=IEA, GO:0030203=TAS, GO:0006024=TAS} carbohydrate metabolic process, glycosaminoglycan biosynthetic process, glycosaminoglycan metabolic process, small molecule metabolic process Golgi lumen, cytoplasm, integral to membrane "heparan sulfate""-glucosamine 3-sulfotransferase 1 activity, sulfotransferase activity""" Human HSBP1 PINC UniProtKB {GO:0006936=GO_REF:0000019, GO:0003714=PMID:9649501, GO:0005634=GO_REF:0000039, GO:0000122=PMID:9649501, GO:0005856=GO_REF:0000019} O75506 Heat shock factor-binding protein 1 protein 20030904 {GO:0006936=IEA, GO:0003714=TAS, GO:0005634=IEA, GO:0000122=TAS, GO:0005856=IEA} muscle contraction, negative regulation of transcription from RNA polymerase II promoter cytoskeleton, nucleus transcription corepressor activity Human HSBP1L1 null null {} null null null null {} null null null HSCB BHF-UCL UniProtKB {GO:0005739=PMID:12938016, GO:0005515=PMID:20668094, GO:0003674=GO_REF:0000015, GO:0005737=PMID:20668094, GO:0016226=PMID:20668094, GO:0006457=GO_REF:0000002, GO:0051087=GO_REF:0000002, GO:0051259=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q8IWL3 Iron-sulfur cluster co-chaperone protein HscB, mitochondrial protein 20100810 {GO:0005739=TAS, GO:0005515=IPI, GO:0003674=ND, GO:0005737=IDA, GO:0016226=IMP, GO:0006457=IEA, GO:0051087=IEA, GO:0051259=IEA, GO:0046872=IEA} iron-sulfur cluster assembly, protein folding, protein oligomerization cytoplasm, mitochondrion chaperone binding, metal ion binding, molecular_function, protein binding Human HSD11B1 Reactome UniProtKB {GO:0070524=GO_REF:0000003, GO:0030324=GO_REF:0000019, GO:0006704=Reactome:REACT_11036, GO:0005789=Reactome:REACT_10043, GO:0003845=Reactome:REACT_10043, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0008202=Reactome:REACT_11057} P28845 Corticosteroid 11-beta-dehydrogenase isozyme 1 protein 20100322 {GO:0070524=IEA, GO:0030324=IEA, GO:0006704=TAS, GO:0005789=TAS, GO:0003845=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0008202=TAS} glucocorticoid biosynthetic process, lung development, small molecule metabolic process, steroid metabolic process endoplasmic reticulum membrane, integral to membrane "11-beta-hydroxysteroid dehydrogenase (NADP+) activity, 11-beta-hydroxysteroid dehydrogenase NAD(P)"" activity""" Human HSD11B1L UniProtKB UniProtKB {GO:0016491=GO_REF:0000037, GO:0005576=GO_REF:0000039} Q7Z5J1 Hydroxysteroid 11-beta-dehydrogenase 1-like protein protein 20130413 {GO:0016491=IEA, GO:0005576=IEA} extracellular region oxidoreductase activity Human UniProtKB-SubCell:SL-0243 HSD11B2 PINC UniProtKB {GO:0032868=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:0005783=GO_REF:0000039, GO:0042493=GO_REF:0000019, GO:0006704=PMID:7859916, GO:0003845=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0032094=GO_REF:0000019, GO:0043231=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0051287=GO_REF:0000019, GO:0002017=GO_REF:0000019, GO:0005496=GO_REF:0000019, GO:0008211=GO_REF:0000019} P80365 Corticosteroid 11-beta-dehydrogenase isozyme 2 protein 20030904 {GO:0032868=IEA, GO:0001666=IEA, GO:0007565=IEA, GO:0005783=IEA, GO:0042493=IEA, GO:0006704=TAS, GO:0003845=IEA, GO:0051384=IEA, GO:0032094=IEA, GO:0043231=IEA, GO:0005737=IEA, GO:0051287=IEA, GO:0002017=IEA, GO:0005496=IEA, GO:0008211=IEA} female pregnancy, glucocorticoid biosynthetic process, glucocorticoid metabolic process, regulation of blood volume by renal aldosterone, response to drug, response to food, response to glucocorticoid stimulus, response to hypoxia, response to insulin stimulus cytoplasm, endoplasmic reticulum, intracellular membrane-bounded organelle "11-beta-hydroxysteroid dehydrogenase NAD(P)"" activity, NAD binding, steroid binding""" Human HSD17B1 Reactome UniProtKB {GO:0008210=PMID:2584224, GO:0004303=Reactome:REACT_25243, GO:0006694=PMID:8547176, GO:0005737=PMID:8547176, GO:0006703=Reactome:REACT_11037, GO:0016491=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0003824=PMID:8547176, GO:0008202=Reactome:REACT_11057, GO:0005829=Reactome:REACT_25243} P14061 Estradiol 17-beta-dehydrogenase 1 protein 20130213 {GO:0008210=TAS, GO:0004303=TAS, GO:0006694=TAS, GO:0005737=TAS, GO:0006703=TAS, GO:0016491=IEA, GO:0044281=TAS, GO:0003824=TAS, GO:0008202=TAS, GO:0005829=TAS} estrogen biosynthetic process, estrogen metabolic process, small molecule metabolic process, steroid biosynthetic process, steroid metabolic process cytoplasm, cytosol catalytic activity, estradiol 17-beta-dehydrogenase activity, oxidoreductase activity Human HSD17B10 IntAct UniProtKB {GO:0005515=PMID:9338779, GO:0006629=PMID:9338779, GO:0005886=PMID:9338779, GO:0005783=GO_REF:0000019, GO:0005743=GO_REF:0000019, GO:0008709=PMID:9338779, GO:0003857=Reactome:REACT_21320, GO:0009083=Reactome:REACT_197, GO:0044281=Reactome:REACT_111217, GO:0008033=GO_REF:0000037, GO:0005739=GO_REF:0000024, GO:0034641=Reactome:REACT_13, GO:0005737=PMID:9338779, GO:0005759=Reactome:REACT_21320, GO:0047015=GO_REF:0000003, GO:0016491=GO_REF:0000002} Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 protein 20130415 {GO:0005515=IPI, GO:0006629=TAS, GO:0005886=TAS, GO:0005783=IEA, GO:0005743=IEA, GO:0008709=TAS, GO:0003857=EXP, GO:0009083=TAS, GO:0044281=TAS, GO:0008033=IEA, GO:0005739=ISS, GO:0034641=TAS, GO:0005737=TAS, GO:0005759=TAS, GO:0047015=IEA, GO:0016491=IEA} branched-chain amino acid catabolic process, cellular nitrogen compound metabolic process, lipid metabolic process, small molecule metabolic process, tRNA processing cytoplasm, endoplasmic reticulum, mitochondrial inner membrane, mitochondrial matrix, mitochondrion, plasma membrane 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity, 3-hydroxyacyl-CoA dehydrogenase activity, cholate 7-alpha-dehydrogenase activity, oxidoreductase activity, protein binding Human UniProtKB:P05067 HSD17B11 HGNC UniProtKB {GO:0005737=PMID:12697717, GO:0004303=GO_REF:0000003, GO:0006694=GO_REF:0000037, GO:0016491=GO_REF:0000002, GO:0016229=PMID:12697717, GO:0005576=GO_REF:0000039, GO:0006710=PMID:12697717} Q8NBQ5 Estradiol 17-beta-dehydrogenase 11 protein 20071017 {GO:0005737=IDA, GO:0004303=IEA, GO:0006694=IEA, GO:0016491=IEA, GO:0016229=IDA, GO:0005576=IEA, GO:0006710=IDA} androgen catabolic process, steroid biosynthetic process cytoplasm, extracellular region estradiol 17-beta-dehydrogenase activity, oxidoreductase activity, steroid dehydrogenase activity Human HSD17B12 InterPro UniProtKB {GO:0005515=PMID:20937905, GO:0004303=GO_REF:0000003, GO:0006703=GO_REF:0000041, GO:0005518=GO_REF:0000019, GO:0010811=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0035338=Reactome:REACT_1319, GO:0031012=GO_REF:0000019, GO:0030198=GO_REF:0000019, GO:0019432=Reactome:REACT_1190, GO:0016491=GO_REF:0000002, GO:0005789=Reactome:REACT_22155, GO:0006633=GO_REF:0000041, GO:0016021=GO_REF:0000037, GO:0001968=GO_REF:0000019, GO:0008201=GO_REF:0000019, GO:0044255=Reactome:REACT_22279} Q96EA9 Estradiol 17-beta-dehydrogenase 12 protein 20130413 {GO:0005515=IPI, GO:0004303=IEA, GO:0006703=IEA, GO:0005518=IEA, GO:0010811=IEA, GO:0044281=TAS, GO:0035338=TAS, GO:0031012=IEA, GO:0030198=IEA, GO:0019432=TAS, GO:0016491=IEA, GO:0005789=TAS, GO:0006633=IEA, GO:0016021=IEA, GO:0001968=IEA, GO:0008201=IEA, GO:0044255=TAS} cellular lipid metabolic process, estrogen biosynthetic process, extracellular matrix organization, fatty acid biosynthetic process, long-chain fatty-acyl-CoA biosynthetic process, positive regulation of cell-substrate adhesion, small molecule metabolic process, triglyceride biosynthetic process endoplasmic reticulum membrane, extracellular matrix, integral to membrane collagen binding, estradiol 17-beta-dehydrogenase activity, fibronectin binding, heparin binding, oxidoreductase activity, protein binding Human InterPro:IPR002198 HSD17B14 HPA UniProtKB {GO:0005515=PMID:19060904, GO:0006706=PMID:17067289, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0004303=PMID:17067289, GO:0016491=GO_REF:0000002, GO:0047045=PMID:17067289, GO:0005829=PMID:17067289} Q9BPX1 17-beta-hydroxysteroid dehydrogenase 14 protein 20100326 {GO:0005515=IPI, GO:0006706=IDA, GO:0005813=IDA, GO:0005737=IDA, GO:0004303=IDA, GO:0016491=IEA, GO:0047045=IDA, GO:0005829=IDA} steroid catabolic process centrosome, cytoplasm, cytosol estradiol 17-beta-dehydrogenase activity, oxidoreductase activity, protein binding, testosterone 17-beta-dehydrogenase (NADP+) activity Human HSD17B3 InterPro UniProtKB {GO:0030539=PMID:8075637, GO:0061370=GO_REF:0000041, GO:0006702=Reactome:REACT_11059, GO:0016491=GO_REF:0000002, GO:0005789=Reactome:REACT_9948, GO:0044281=Reactome:REACT_111217, GO:0047045=GO_REF:0000003, GO:0008202=Reactome:REACT_11057, GO:0043231=PMID:8075637} Q5U0Q6 Hydroxysteroid (17-beta) dehydrogenase 3 protein 20130413 {GO:0030539=TAS, GO:0061370=IEA, GO:0006702=TAS, GO:0016491=IEA, GO:0005789=TAS, GO:0044281=TAS, GO:0047045=IEA, GO:0008202=TAS, GO:0043231=TAS} androgen biosynthetic process, male genitalia development, small molecule metabolic process, steroid metabolic process, testosterone biosynthetic process endoplasmic reticulum membrane, intracellular membrane-bounded organelle oxidoreductase activity, testosterone 17-beta-dehydrogenase (NADP+) activity Human InterPro:IPR002198|InterPro:IPR020904 HSD17B4 HPA UniProtKB {GO:0000038=GO_REF:0000019, GO:0005782=Reactome:REACT_121210, GO:0006699=Reactome:REACT_11054, GO:0044281=Reactome:REACT_111217, GO:0042803=PMID:15644212, GO:0043231=GO_REF:0000052, GO:0005739=GO_REF:0000019, GO:0032934=GO_REF:0000002, GO:0060009=GO_REF:0000019, GO:0008206=Reactome:REACT_11040, GO:0044255=Reactome:REACT_16957, GO:0005778=PMID:21525035, GO:0005777=PMID:9482850, GO:0006635=PMID:10400999, GO:0008209=PMID:7487879, GO:0005102=PMID:20178365, GO:0003857=Reactome:REACT_16976, GO:0036109=Reactome:REACT_121147, GO:0033989=Reactome:REACT_10019, GO:0033559=Reactome:REACT_121284, GO:0008210=PMID:7487879, GO:0036112=PMID:9089413, GO:0036111=PMID:9482850, GO:0016508=Reactome:REACT_121210, GO:0016491=GO_REF:0000038, GO:0033540=Reactome:REACT_17062, GO:0016853=GO_REF:0000037} P51659 Peroxisomal multifunctional enzyme type 2 protein 20111111 {GO:0000038=IEA, GO:0005782=TAS, GO:0006699=TAS, GO:0044281=TAS, GO:0042803=IDA, GO:0043231=IDA, GO:0005739=IEA, GO:0032934=IEA, GO:0060009=IEA, GO:0008206=TAS, GO:0044255=TAS, GO:0005778=IDA, GO:0005777=NAS, GO:0006635=IDA, GO:0008209=IDA, GO:0005102=IPI, GO:0003857=TAS, GO:0036109=TAS, GO:0033989=TAS, GO:0033559=TAS, GO:0008210=IDA, GO:0036112=IDA, GO:0036111=IDA, GO:0016508=TAS, GO:0016491=IEA, GO:0033540=TAS, GO:0016853=IEA} Sertoli cell development, alpha-linolenic acid metabolic process, androgen metabolic process, bile acid biosynthetic process, bile acid metabolic process, cellular lipid metabolic process, estrogen metabolic process, fatty acid beta-oxidation, fatty acid beta-oxidation using acyl-CoA oxidase, medium-chain fatty-acyl-CoA metabolic process, small molecule metabolic process, unsaturated fatty acid metabolic process, very long-chain fatty acid metabolic process, very long-chain fatty-acyl-CoA metabolic process intracellular membrane-bounded organelle, mitochondrion, peroxisomal matrix, peroxisomal membrane, peroxisome 3-hydroxyacyl-CoA dehydrogenase activity, 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity, isomerase activity, long-chain-enoyl-CoA hydratase activity, oxidoreductase activity, protein homodimerization activity, receptor binding, sterol binding Human HSD17B7 InterPro UniProtKB {GO:0006695=Reactome:REACT_9405, GO:0004303=GO_REF:0000003, GO:0005148=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0006703=GO_REF:0000041, GO:0005789=Reactome:REACT_10079, GO:0016491=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0000253=GO_REF:0000003} Q5T249 HCG2024989, isoform CRA_g protein 20130413 {GO:0006695=TAS, GO:0004303=IEA, GO:0005148=IEA, GO:0005886=IEA, GO:0006703=IEA, GO:0005789=TAS, GO:0016491=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0000253=IEA} cholesterol biosynthetic process, estrogen biosynthetic process, small molecule metabolic process endoplasmic reticulum membrane, integral to membrane, plasma membrane 3-keto sterol reductase activity, estradiol 17-beta-dehydrogenase activity, oxidoreductase activity, prolactin receptor binding Human InterPro:IPR002198 HSD17B8 UniProtKB UniProtKB {GO:0005515=PMID:19571038, GO:0004303=PMID:17978863, GO:0005886=GO_REF:0000019, GO:0005759=PMID:19571038, GO:0006703=PMID:17978863, GO:0050327=GO_REF:0000019, GO:0008209=GO_REF:0000019, GO:0047035=GO_REF:0000003, GO:0003857=PMID:19571038, GO:0006633=GO_REF:0000041, GO:0005740=GO_REF:0000019} Q92506 Estradiol 17-beta-dehydrogenase 8 protein 20100428 {GO:0005515=IPI, GO:0004303=IDA, GO:0005886=IEA, GO:0005759=IDA, GO:0006703=IDA, GO:0050327=IEA, GO:0008209=IEA, GO:0047035=IEA, GO:0003857=IDA, GO:0006633=IEA, GO:0005740=IEA} androgen metabolic process, estrogen biosynthetic process, fatty acid biosynthetic process mitochondrial envelope, mitochondrial matrix, plasma membrane 3-hydroxyacyl-CoA dehydrogenase activity, estradiol 17-beta-dehydrogenase activity, protein binding, testosterone 17-beta-dehydrogenase (NAD+) activity, testosterone dehydrogenase (NAD+) activity Human HSD3B1 InterPro UniProtKB {GO:0006705=Reactome:REACT_11047, GO:0004769=PMID:1944309, GO:0006694=GO_REF:0000002, GO:0006702=Reactome:REACT_11059, GO:0006703=PMID:1944309, GO:0006704=Reactome:REACT_11036, GO:0005743=PMID:8274411, GO:0044281=Reactome:REACT_111217, GO:0003854=GO_REF:0000002, GO:0005758=PMID:8274411, GO:0030868=GO_REF:0000024, GO:0005789=Reactome:REACT_10056, GO:0016021=GO_REF:0000037, GO:0008202=Reactome:REACT_11057} Q5TDG2 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 protein 20130413 {GO:0006705=TAS, GO:0004769=ISS, GO:0006694=IEA, GO:0006702=TAS, GO:0006703=TAS, GO:0006704=TAS, GO:0005743=IDA, GO:0044281=TAS, GO:0003854=IEA, GO:0005758=IDA, GO:0030868=ISS, GO:0005789=TAS, GO:0016021=IEA, GO:0008202=TAS} androgen biosynthetic process, estrogen biosynthetic process, glucocorticoid biosynthetic process, mineralocorticoid biosynthetic process, small molecule metabolic process, steroid biosynthetic process, steroid metabolic process endoplasmic reticulum membrane, integral to membrane, mitochondrial inner membrane, mitochondrial intermembrane space, smooth endoplasmic reticulum membrane 3-beta-hydroxy-delta5-steroid dehydrogenase activity, steroid delta-isomerase activity Human InterPro:IPR002225 HSD3B2 InterPro UniProtKB {GO:0006705=Reactome:REACT_11047, GO:0004769=PMID:1944309, GO:0006694=GO_REF:0000002, GO:0031966=PMID:1944309, GO:0005783=PMID:1944309, GO:0006702=Reactome:REACT_11059, GO:0006704=Reactome:REACT_11036, GO:0005743=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0003854=GO_REF:0000002, GO:0005758=GO_REF:0000024, GO:0030868=GO_REF:0000024, GO:0005789=Reactome:REACT_10056, GO:0016021=PMID:1944309, GO:0008202=Reactome:REACT_11057} Q5QP01 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 protein 20130413 {GO:0006705=TAS, GO:0004769=IDA, GO:0006694=IEA, GO:0031966=NAS, GO:0005783=NAS, GO:0006702=TAS, GO:0006704=TAS, GO:0005743=ISS, GO:0044281=TAS, GO:0003854=IEA, GO:0005758=ISS, GO:0030868=ISS, GO:0005789=TAS, GO:0016021=NAS, GO:0008202=TAS} androgen biosynthetic process, glucocorticoid biosynthetic process, mineralocorticoid biosynthetic process, small molecule metabolic process, steroid biosynthetic process, steroid metabolic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial membrane, smooth endoplasmic reticulum membrane 3-beta-hydroxy-delta5-steroid dehydrogenase activity, steroid delta-isomerase activity Human InterPro:IPR002225 HSD3B7 Reactome UniProtKB {GO:0006694=GO_REF:0000002, GO:0006699=Reactome:REACT_11054, GO:0005789=Reactome:REACT_10115, GO:0008206=Reactome:REACT_11040, GO:0044281=Reactome:REACT_111217, GO:0005575=GO_REF:0000015, GO:0047016=GO_REF:0000003, GO:0016021=GO_REF:0000037, GO:0003854=PMID:11067870} Q9H2F3 3 beta-hydroxysteroid dehydrogenase type 7 protein 20130301 {GO:0006694=IEA, GO:0006699=TAS, GO:0005789=TAS, GO:0008206=TAS, GO:0044281=TAS, GO:0005575=ND, GO:0047016=IEA, GO:0016021=IEA, GO:0003854=NAS} bile acid biosynthetic process, bile acid metabolic process, small molecule metabolic process, steroid biosynthetic process cellular_component, endoplasmic reticulum membrane, integral to membrane 3-beta-hydroxy-delta5-steroid dehydrogenase activity, cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity Human HSDL1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0016491=GO_REF:0000002} Q3SXM5 Inactive hydroxysteroid dehydrogenase-like protein 1 protein 20130413 {GO:0005739=IEA, GO:0016491=IEA} mitochondrion oxidoreductase activity Human UniProtKB-SubCell:SL-0173 HSDL2 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0032934=GO_REF:0000002, GO:0016491=GO_REF:0000037, GO:0005777=PMID:19703561} Q6YN16 Hydroxysteroid dehydrogenase-like protein 2 protein 20120517 {GO:0005739=IEA, GO:0003674=ND, GO:0008150=ND, GO:0032934=IEA, GO:0016491=IEA, GO:0005777=IDA} biological_process mitochondrion, peroxisome molecular_function, oxidoreductase activity, sterol binding Human HSF1 HPA UniProtKB {GO:0005515=PMID:23352416, GO:0090231=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0008285=GO_REF:0000019, GO:0009408=GO_REF:0000002, GO:0001162=PMID:10561509, GO:0005730=GO_REF:0000052, GO:0060136=GO_REF:0000019, GO:0001892=GO_REF:0000019, GO:0032720=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0007283=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0034605=PMID:17897941, GO:0043565=GO_REF:0000002, GO:0043234=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0045944=PMID:10561509, GO:0003682=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0006468=GO_REF:0000019, GO:0045120=GO_REF:0000019, GO:0040018=GO_REF:0000019, GO:0007143=GO_REF:0000019} Q00613 Heat shock factor protein 1 protein 20101115 {GO:0005515=IPI, GO:0090231=IEA, GO:0003700=IEA, GO:0008285=IEA, GO:0009408=IEA, GO:0001162=IDA, GO:0005730=IDA, GO:0060136=IEA, GO:0001892=IEA, GO:0032720=IEA, GO:0005634=IDA, GO:0007283=IEA, GO:0006351=IEA, GO:0034605=IDA, GO:0043565=IEA, GO:0043234=IEA, GO:0005737=IDA, GO:0045944=IDA, GO:0003682=IEA, GO:0032496=IEA, GO:0006468=IEA, GO:0045120=IEA, GO:0040018=IEA, GO:0007143=IEA} cellular response to heat, embryonic placenta development, embryonic process involved in female pregnancy, female meiosis, negative regulation of cell proliferation, negative regulation of tumor necrosis factor production, positive regulation of multicellular organism growth, positive regulation of transcription from RNA polymerase II promoter, protein phosphorylation, regulation of spindle checkpoint, response to heat, response to lipopolysaccharide, spermatogenesis, transcription, DNA-dependent cytoplasm, nucleolus, nucleus, pronucleus, protein complex RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding, chromatin binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human HSF2 HPA UniProtKB {GO:0005737=GO_REF:0000039, GO:0003700=GO_REF:0000002, GO:0006366=PMID:1871106, GO:0045944=PMID:10561509, GO:0003713=PMID:1871106, GO:0001162=PMID:10561509, GO:0005730=GO_REF:0000052, GO:0006950=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0007283=GO_REF:0000019, GO:0042803=GO_REF:0000019} Q03933 Heat shock factor protein 2 protein 20111111 {GO:0005737=IEA, GO:0003700=IEA, GO:0006366=TAS, GO:0045944=IDA, GO:0003713=TAS, GO:0001162=IDA, GO:0005730=IDA, GO:0006950=IEA, GO:0005634=IDA, GO:0007283=IEA, GO:0042803=IEA} positive regulation of transcription from RNA polymerase II promoter, response to stress, spermatogenesis, transcription from RNA polymerase II promoter cytoplasm, nucleolus, nucleus RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding, protein homodimerization activity, sequence-specific DNA binding transcription factor activity, transcription coactivator activity NOT Human HSF2BP PINC UniProtKB {GO:0006366=PMID:9651507, GO:0006950=GO_REF:0000038, GO:0007283=PMID:9651507, GO:0005829=PMID:16780588} O75031 Heat shock factor 2-binding protein protein 20030904 {GO:0006366=TAS, GO:0006950=IEA, GO:0007283=TAS, GO:0005829=IDA} response to stress, spermatogenesis, transcription from RNA polymerase II promoter cytosol Human HSF4 PINC UniProtKB {GO:0006355=PMID:8972228, GO:0008284=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0003714=PMID:8972228, GO:0045597=GO_REF:0000019, GO:0006950=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0000122=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000019, GO:0070207=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0043010=GO_REF:0000019, GO:0048468=GO_REF:0000019, GO:0033169=GO_REF:0000019} Q9ULV5 Heat shock factor protein 4 protein 20030904 {GO:0006355=TAS, GO:0008284=IEA, GO:0003700=IEA, GO:0003714=TAS, GO:0045597=IEA, GO:0006950=IEA, GO:0005634=IEA, GO:0000122=IEA, GO:0006351=IEA, GO:0043565=IEA, GO:0070207=IEA, GO:0045944=IEA, GO:0043010=IEA, GO:0048468=IEA, GO:0033169=IEA} camera-type eye development, cell development, histone H3-K9 demethylation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of cell differentiation, positive regulation of cell proliferation, positive regulation of transcription from RNA polymerase II promoter, protein homotrimerization, regulation of transcription, DNA-dependent, response to stress, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human HSFX1 IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0043565=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0003700=GO_REF:0000002, GO:0005634=GO_REF:0000054, GO:0006351=GO_REF:0000037} Q9UBD0 Heat shock transcription factor, X-linked protein 20130415 {GO:0005515=IPI, GO:0043565=IEA, GO:0005737=IEA, GO:0003700=IEA, GO:0005634=IDA, GO:0006351=IEA} transcription, DNA-dependent cytoplasm, nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:P54253 HSFY1 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0003700=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q96LI6 Heat shock transcription factor, Y-linked protein 20130413 {GO:0043565=IEA, GO:0005737=IEA, GO:0003700=IEA, GO:0005634=IEA, GO:0006351=IEA} transcription, DNA-dependent cytoplasm, nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0086 HSH2D UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039} Q96JZ2 Hematopoietic SH2 domain-containing protein protein 20130413 {GO:0005737=IEA, GO:0005634=IEA} cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 HSP90AA1 InterPro UniProtKB {GO:0006986=PMID:2527334, GO:0005515=PMID:21988832, GO:0006200=PMID:15937123, GO:0005886=Reactome:REACT_12459, GO:0050999=Reactome:REACT_12477, GO:0044281=Reactome:REACT_111217, GO:0045040=PMID:15644312, GO:0042803=PMID:11470816, GO:0042802=PMID:21360678, GO:0045429=GO_REF:0000024, GO:0005829=Reactome:REACT_116154, GO:0042026=PMID:9660753, GO:0000166=PMID:11470816, GO:0006457=GO_REF:0000002, GO:0007411=Reactome:REACT_18266, GO:0000086=Reactome:REACT_2203, GO:0046209=Reactome:REACT_12508, GO:0030235=PMID:15937123, GO:0051131=PMID:15644312, GO:0006839=PMID:12526792, GO:0016887=PMID:15937123, GO:0042470=GO_REF:0000039, GO:0030911=PMID:9660753, GO:0006950=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0007165=PMID:11470816, GO:0045087=Reactome:REACT_6802, GO:0051082=GO_REF:0000002, GO:0000278=Reactome:REACT_152, GO:0038096=Reactome:REACT_160123} Q86U12 Full-length cDNA clone CS0CAP007YF18 of Thymus of Homo sapiens (human) protein 20130413 {GO:0006986=NAS, GO:0005515=IPI, GO:0006200=IDA, GO:0005886=TAS, GO:0050999=TAS, GO:0044281=TAS, GO:0045040=IDA, GO:0042803=TAS, GO:0042802=IPI, GO:0045429=ISS, GO:0005829=TAS, GO:0042026=TAS, GO:0000166=TAS, GO:0006457=IEA, GO:0007411=TAS, GO:0000086=TAS, GO:0046209=TAS, GO:0030235=IDA, GO:0051131=IDA, GO:0006839=TAS, GO:0016887=IDA, GO:0042470=IEA, GO:0030911=IDA, GO:0006950=IEA, GO:0005524=IEA, GO:0007165=NAS, GO:0045087=TAS, GO:0051082=IEA, GO:0000278=TAS, GO:0038096=TAS} ATP catabolic process, Fc-gamma receptor signaling pathway involved in phagocytosis, G2/M transition of mitotic cell cycle, axon guidance, chaperone-mediated protein complex assembly, innate immune response, mitochondrial transport, mitotic cell cycle, nitric oxide metabolic process, positive regulation of nitric oxide biosynthetic process, protein folding, protein import into mitochondrial outer membrane, protein refolding, regulation of nitric-oxide synthase activity, response to stress, response to unfolded protein, signal transduction, small molecule metabolic process cytosol, melanosome, plasma membrane ATP binding, ATPase activity, TPR domain binding, identical protein binding, nitric-oxide synthase regulator activity, nucleotide binding, protein binding, protein homodimerization activity, unfolded protein binding Human InterPro:IPR001404 HSP90AA2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0006457=GO_REF:0000002, GO:0006950=GO_REF:0000037, GO:0051082=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q14568 Putative heat shock protein HSP 90-alpha A2 protein 20130413 {GO:0005737=IEA, GO:0006457=IEA, GO:0006950=IEA, GO:0051082=IEA, GO:0005524=IEA} protein folding, response to stress cytoplasm ATP binding, unfolded protein binding Human UniProtKB-SubCell:SL-0086 HSP90AB1 InterPro UniProtKB {GO:0005515=PMID:23455922, GO:0006986=PMID:2768249, GO:0009651=GO_REF:0000019, GO:0033160=GO_REF:0000019, GO:0071902=GO_REF:0000019, GO:0032435=PMID:16280321, GO:0031526=GO_REF:0000019, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_75877, GO:0045429=GO_REF:0000024, GO:0032092=GO_REF:0000019, GO:0060334=PMID:16280321, GO:0005739=GO_REF:0000019, GO:0016323=GO_REF:0000019, GO:0005737=GO_REF:0000029, GO:0016324=GO_REF:0000019, GO:0043524=GO_REF:0000019, GO:0060338=PMID:16280321, GO:0008180=PMID:18850735, GO:0007411=Reactome:REACT_18266, GO:0006457=GO_REF:0000002, GO:0030235=GO_REF:0000024, GO:0017098=GO_REF:0000019, GO:0042470=GO_REF:0000039, GO:0030911=GO_REF:0000024, GO:0009986=GO_REF:0000019, GO:0019901=GO_REF:0000019, GO:0016234=GO_REF:0000019, GO:0032564=GO_REF:0000019, GO:0006950=GO_REF:0000002, GO:0001890=GO_REF:0000019, GO:0005525=GO_REF:0000019, GO:0005524=GO_REF:0000002, GO:0002135=GO_REF:0000019, GO:0002134=GO_REF:0000019, GO:0044325=GO_REF:0000019, GO:0045793=GO_REF:0000019, GO:0071407=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0051082=GO_REF:0000002, GO:0038096=Reactome:REACT_160123} Q5T9W8 Heat shock protein HSP 90-beta protein 20130413 {GO:0005515=IPI, GO:0006986=NAS, GO:0009651=IEA, GO:0033160=IEA, GO:0071902=IEA, GO:0032435=IMP, GO:0031526=IEA, GO:0035872=TAS, GO:0005829=TAS, GO:0045429=ISS, GO:0032092=IEA, GO:0060334=IMP, GO:0005739=IEA, GO:0016323=IEA, GO:0005737=NAS, GO:0016324=IEA, GO:0043524=IEA, GO:0060338=IMP, GO:0008180=IDA, GO:0007411=TAS, GO:0006457=IEA, GO:0030235=ISS, GO:0017098=IEA, GO:0042470=IEA, GO:0030911=ISS, GO:0009986=IEA, GO:0019901=IEA, GO:0016234=IEA, GO:0032564=IEA, GO:0006950=IEA, GO:0001890=IEA, GO:0005525=IEA, GO:0005524=IEA, GO:0002135=IEA, GO:0002134=IEA, GO:0044325=IEA, GO:0045793=IEA, GO:0071407=IEA, GO:0045087=TAS, GO:0051082=IEA, GO:0038096=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, axon guidance, cellular response to organic cyclic compound, innate immune response, negative regulation of neuron apoptotic process, negative regulation of proteasomal ubiquitin-dependent protein catabolic process, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, placenta development, positive regulation of cell size, positive regulation of nitric oxide biosynthetic process, positive regulation of protein binding, positive regulation of protein import into nucleus, translocation, positive regulation of protein serine/threonine kinase activity, protein folding, regulation of interferon-gamma-mediated signaling pathway, regulation of type I interferon-mediated signaling pathway, response to salt stress, response to stress, response to unfolded protein apical plasma membrane, basolateral plasma membrane, brush border membrane, cell surface, cytoplasm, cytosol, inclusion body, melanosome, mitochondrion, signalosome ATP binding, CTP binding, GTP binding, TPR domain binding, UTP binding, dATP binding, ion channel binding, nitric-oxide synthase regulator activity, protein binding, protein kinase binding, sulfonylurea receptor binding, unfolded protein binding Human InterPro:IPR001404|InterPro:IPR019805 HSP90B1 HPA UniProtKB {GO:0005515=PMID:18264092, GO:0048471=PMID:10497210, GO:0005783=GO_REF:0000052, GO:0003723=PMID:11958450, GO:0031247=PMID:19000834, GO:0015031=PMID:15845869, GO:0030968=Reactome:REACT_18356, GO:0005829=PMID:9596688, GO:0044459=GO_REF:0000019, GO:0006457=GO_REF:0000002, GO:0042470=GO_REF:0000039, GO:0001666=PMID:15620698, GO:0043066=PMID:10497210, GO:0051208=PMID:15192333, GO:0019903=PMID:19000834, GO:0005509=PMID:10497210, GO:0006950=GO_REF:0000002, GO:0046790=PMID:11958450, GO:0030496=PMID:15166316, GO:0002224=Reactome:REACT_6966, GO:0030433=PMID:18264092, GO:0005524=GO_REF:0000037, GO:0071318=PMID:19000834, GO:0045087=Reactome:REACT_6802, GO:0005789=PMID:10497210, GO:0005788=Reactome:REACT_118729, GO:0043666=PMID:19000834, GO:0051082=GO_REF:0000002, GO:0006987=Reactome:REACT_18348, GO:0044267=Reactome:REACT_17015, GO:0050750=PMID:15082773} P14625 Endoplasmin protein 20080205 {GO:0005515=IPI, GO:0048471=IDA, GO:0005783=IDA, GO:0003723=IDA, GO:0031247=IDA, GO:0015031=NAS, GO:0030968=TAS, GO:0005829=IDA, GO:0044459=IEA, GO:0006457=IEA, GO:0042470=IEA, GO:0001666=IDA, GO:0043066=IMP, GO:0051208=NAS, GO:0019903=IDA, GO:0005509=TAS, GO:0006950=IEA, GO:0046790=IPI, GO:0030496=IDA, GO:0002224=TAS, GO:0030433=IMP, GO:0005524=IEA, GO:0071318=IDA, GO:0045087=TAS, GO:0005789=IDA, GO:0005788=TAS, GO:0043666=IDA, GO:0051082=IEA, GO:0006987=TAS, GO:0044267=TAS, GO:0050750=IDA} ER-associated protein catabolic process, actin rod assembly, activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, cellular response to ATP, endoplasmic reticulum unfolded protein response, innate immune response, negative regulation of apoptotic process, protein folding, protein transport, regulation of phosphoprotein phosphatase activity, response to hypoxia, response to stress, sequestering of calcium ion, toll-like receptor signaling pathway cytosol, endoplasmic reticulum, endoplasmic reticulum lumen, endoplasmic reticulum membrane, melanosome, midbody, perinuclear region of cytoplasm, plasma membrane part ATP binding, RNA binding, calcium ion binding, low-density lipoprotein particle receptor binding, protein binding, protein phosphatase binding, unfolded protein binding, virion binding Human HSPA12A UniProtKB UniProtKB {GO:0005524=GO_REF:0000037} O43301 Heat shock 70 kDa protein 12A protein 20130413 {GO:0005524=IEA} ATP binding Human UniProtKB-KW:KW-0067 HSPA13 PINC UniProtKB {GO:0005783=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0043231=PMID:8131751} P48723 Heat shock 70 kDa protein 13 protein 20030904 {GO:0005783=IEA, GO:0005524=IEA, GO:0043231=TAS} endoplasmic reticulum, intracellular membrane-bounded organelle ATP binding Human HSPA14 UniProtKB UniProtKB {GO:0005515=PMID:16002468, GO:0006950=GO_REF:0000038, GO:0005840=PMID:16002468, GO:0051083=PMID:16002468, GO:0005524=GO_REF:0000037, GO:0005829=PMID:16002468} Q0VDF9 Heat shock 70 kDa protein 14 protein 20110120 {GO:0005515=IPI, GO:0006950=IEA, GO:0005840=IDA, GO:0051083=TAS, GO:0005524=IEA, GO:0005829=IDA} 'de novo' cotranslational protein folding, response to stress cytosol, ribosome ATP binding, protein binding Human UniProtKB:Q99543 HSPA1A BHF-UCL UniProtKB {GO:0006986=PMID:10859165, GO:0005515=PMID:15603737, GO:0090084=PMID:15603737, GO:0010467=Reactome:REACT_71, GO:0030308=PMID:9553041, GO:0048471=PMID:15603737, GO:0008285=PMID:9553041, GO:0005783=PMID:16130169, GO:0005634=PMID:10205060, GO:0005829=Reactome:REACT_25315, GO:0005739=PMID:16130169, GO:0042026=PMID:15603737, GO:0005737=PMID:9553041, GO:0008180=PMID:18850735, GO:0031625=PMID:15603737, GO:0043066=PMID:16130169, GO:0016235=PMID:15885686, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0016234=PMID:15603737, GO:0006402=PMID:10205060, GO:0005524=GO_REF:0000037, GO:0047485=PMID:9553041, GO:0016607=PMID:9553041, GO:0044183=PMID:15603737, GO:0030529=PMID:17289661, GO:0051082=PMID:16130169} P08107 Heat shock 70 kDa protein 1A/1B protein 20100111 {GO:0006986=IDA, GO:0005515=IPI, GO:0090084=IDA, GO:0010467=TAS, GO:0030308=IMP, GO:0048471=IDA, GO:0008285=IMP, GO:0005783=TAS, GO:0005634=IDA, GO:0005829=TAS, GO:0005739=TAS, GO:0042026=IDA, GO:0005737=IDA, GO:0008180=IDA, GO:0031625=IPI, GO:0043066=TAS, GO:0016235=IDA, GO:0016070=TAS, GO:0016071=TAS, GO:0016234=IDA, GO:0006402=IDA, GO:0005524=IEA, GO:0047485=IPI, GO:0016607=IDA, GO:0044183=IDA, GO:0030529=IDA, GO:0051082=TAS} RNA metabolic process, gene expression, mRNA catabolic process, mRNA metabolic process, negative regulation of apoptotic process, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of inclusion body assembly, protein refolding, response to unfolded protein aggresome, cytoplasm, cytosol, endoplasmic reticulum, inclusion body, mitochondrion, nuclear speck, nucleus, perinuclear region of cytoplasm, ribonucleoprotein complex, signalosome ATP binding, protein N-terminus binding, protein binding, protein binding involved in protein folding, ubiquitin protein ligase binding, unfolded protein binding Human UniProtKB:O60260 HSPA1B null null {} null null null null {} null null null HSPA1L PINC UniProtKB {GO:0006986=PMID:9685725, GO:0008180=PMID:18850735, GO:0005759=GO_REF:0000019, GO:0005524=GO_REF:0000037} P34931 Heat shock 70 kDa protein 1-like protein 20040806 {GO:0006986=TAS, GO:0008180=IDA, GO:0005759=IEA, GO:0005524=IEA} response to unfolded protein mitochondrial matrix, signalosome ATP binding Human HSPA2 IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0006986=PMID:7829106, GO:0000795=GO_REF:0000019, GO:0051861=GO_REF:0000019, GO:0009986=PMID:12493773, GO:0007286=GO_REF:0000019, GO:0036128=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0005739=GO_REF:0000019, GO:0070194=GO_REF:0000019, GO:0051082=PMID:3037489, GO:0001673=GO_REF:0000019, GO:0031662=GO_REF:0000019, GO:0007141=GO_REF:0000019, GO:0007140=PMID:8622925} P54652 Heat shock-related 70 kDa protein 2 protein 20130415 {GO:0005515=IPI, GO:0006986=TAS, GO:0000795=IEA, GO:0051861=IEA, GO:0009986=IDA, GO:0007286=IEA, GO:0036128=ISS, GO:0005524=IEA, GO:0005739=IEA, GO:0070194=IEA, GO:0051082=TAS, GO:0001673=IEA, GO:0031662=IEA, GO:0007141=IEA, GO:0007140=TAS} male meiosis, male meiosis I, positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M, response to unfolded protein, spermatid development, synaptonemal complex disassembly CatSper complex, cell surface, male germ cell nucleus, mitochondrion, synaptonemal complex ATP binding, glycolipid binding, protein binding, unfolded protein binding Human UniProtKB:Q9NZL4 HSPA4 HPA UniProtKB {GO:0006986=PMID:8335910, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0051131=PMID:15644312, GO:0045040=PMID:15644312, GO:0005524=PMID:8335910} P34932 Heat shock 70 kDa protein 4 protein 20101115 {GO:0006986=NAS, GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0051131=IDA, GO:0045040=IDA, GO:0005524=NAS} chaperone-mediated protein complex assembly, protein import into mitochondrial outer membrane, response to unfolded protein cytoplasm, nucleolus, nucleus ATP binding Human HSPA4L UniProtKB UniProtKB {GO:0006986=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0006457=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0005524=GO_REF:0000024} O95757 Heat shock 70 kDa protein 4L protein 20041006 {GO:0006986=ISS, GO:0005737=ISS, GO:0006457=ISS, GO:0005634=ISS, GO:0005524=ISS} protein folding, response to unfolded protein cytoplasm, nucleus ATP binding Human UniProtKB:P83581 HSPA5 GOC UniProtKB {GO:0005515=PMID:18064632, GO:0006983=GO_REF:0000019, GO:0006200=GO_REF:0000024, GO:0005783=PMID:16223484, GO:0051087=PMID:19816510, GO:0030176=PMID:11181571, GO:0005634=PMID:11943137, GO:0030968=PMID:19816510, GO:0051787=PMID:18400946, GO:0008180=PMID:18850735, GO:0021680=GO_REF:0000019, GO:0034663=PMID:18400946, GO:0031398=GO_REF:0000019, GO:0042149=PMID:10085239, GO:0030674=GO_REF:0000029, GO:0016887=GO_REF:0000024, GO:0030512=GO_REF:0000019, GO:0031625=PMID:8666824, GO:0042470=GO_REF:0000039, GO:0005793=PMID:15308636, GO:0043066=PMID:12665508, GO:0009986=PMID:12493773, GO:0005509=PMID:16130169, GO:0019904=PMID:12411443, GO:0030168=Reactome:REACT_798, GO:0030496=PMID:15166316, GO:0030433=PMID:19816510, GO:0005524=GO_REF:0000037, GO:0021589=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0005789=Reactome:REACT_115545, GO:0005788=Reactome:REACT_18413, GO:0043022=GO_REF:0000019, GO:0051082=PMID:16130169, GO:0006987=Reactome:REACT_18368, GO:0060904=PMID:19816510, GO:0044267=Reactome:REACT_17015} P11021 78 kDa glucose-regulated protein protein 20130413 {GO:0005515=IPI, GO:0006983=IEA, GO:0006200=ISS, GO:0005783=IDA, GO:0051087=TAS, GO:0030176=IDA, GO:0005634=IMP, GO:0030968=TAS, GO:0051787=IDA, GO:0008180=IDA, GO:0021680=IEA, GO:0034663=IDA, GO:0031398=IEA, GO:0042149=IDA, GO:0030674=NAS, GO:0016887=ISS, GO:0030512=IEA, GO:0031625=IPI, GO:0042470=IEA, GO:0005793=IDA, GO:0043066=IMP, GO:0009986=IDA, GO:0005509=TAS, GO:0019904=IPI, GO:0030168=TAS, GO:0030496=IDA, GO:0030433=TAS, GO:0005524=IEA, GO:0021589=IEA, GO:0007596=TAS, GO:0002576=TAS, GO:0005789=TAS, GO:0005788=TAS, GO:0043022=IEA, GO:0051082=TAS, GO:0006987=TAS, GO:0060904=TAS, GO:0044267=TAS} ATP catabolic process, ER overload response, ER-associated protein catabolic process, activation of signaling protein activity involved in unfolded protein response, blood coagulation, cellular protein metabolic process, cellular response to glucose starvation, cerebellar Purkinje cell layer development, cerebellum structural organization, endoplasmic reticulum unfolded protein response, negative regulation of apoptotic process, negative regulation of transforming growth factor beta receptor signaling pathway, platelet activation, platelet degranulation, positive regulation of protein ubiquitination, regulation of protein folding in endoplasmic reticulum cell surface, endoplasmic reticulum, endoplasmic reticulum chaperone complex, endoplasmic reticulum lumen, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment, integral to endoplasmic reticulum membrane, melanosome, midbody, nucleus, signalosome ATP binding, ATPase activity, calcium ion binding, chaperone binding, misfolded protein binding, protein binding, protein binding, bridging, protein domain specific binding, ribosome binding, ubiquitin protein ligase binding, unfolded protein binding Human UniProtKB:P07823 HSPA6 PINC UniProtKB {GO:0006986=PMID:2327978, GO:0008180=PMID:18850735, GO:0005524=GO_REF:0000037} P17066 Heat shock 70 kDa protein 6 protein 20040806 {GO:0006986=TAS, GO:0008180=IDA, GO:0005524=IEA} response to unfolded protein signalosome ATP binding Human HSPA8 BHF-UCL UniProtKB {GO:0008380=GO_REF:0000037, GO:0006986=PMID:11093761, GO:0005515=PMID:15936278, GO:0010467=Reactome:REACT_71, GO:0042623=PMID:8530083, GO:0005886=Reactome:REACT_23813, GO:0007268=Reactome:REACT_13685, GO:0005634=PMID:20176811, GO:0007269=Reactome:REACT_13723, GO:0005829=Reactome:REACT_25315, GO:0005622=PMID:8713105, GO:0006457=PMID:8530083, GO:0051726=GO_REF:0000019, GO:0005681=GO_REF:0000037, GO:0070062=GO_REF:0000019, GO:0006397=GO_REF:0000037, GO:0000974=PMID:20176811, GO:0042470=GO_REF:0000039, GO:0016070=Reactome:REACT_21257, GO:0009986=PMID:12493773, GO:0016071=Reactome:REACT_20605, GO:0005730=PMID:92266438, GO:0006892=Reactome:REACT_11235, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0030529=PMID:17289661, GO:0051085=GO_REF:0000019, GO:0061202=Reactome:REACT_23973, GO:0051082=GO_REF:0000019, GO:0045892=PMID:10722728, GO:0016044=Reactome:REACT_11123} P11142 Heat shock cognate 71 kDa protein protein 20091209 {GO:0008380=IEA, GO:0006986=NAS, GO:0005515=IPI, GO:0010467=TAS, GO:0042623=NAS, GO:0005886=TAS, GO:0007268=TAS, GO:0005634=IDA, GO:0007269=TAS, GO:0005829=TAS, GO:0005622=NAS, GO:0006457=NAS, GO:0051726=IEA, GO:0005681=IEA, GO:0070062=IEA, GO:0006397=IEA, GO:0000974=IDA, GO:0042470=IEA, GO:0016070=TAS, GO:0009986=IDA, GO:0016071=TAS, GO:0005730=IDA, GO:0006892=TAS, GO:0005524=IEA, GO:0006351=IEA, GO:0019048=IEA, GO:0030529=IDA, GO:0051085=IEA, GO:0061202=TAS, GO:0051082=IEA, GO:0045892=IDA, GO:0016044=TAS} RNA metabolic process, RNA splicing, cellular membrane organization, chaperone mediated protein folding requiring cofactor, gene expression, mRNA metabolic process, mRNA processing, negative regulation of transcription, DNA-dependent, neurotransmitter secretion, post-Golgi vesicle-mediated transport, protein folding, regulation of cell cycle, response to unfolded protein, synaptic transmission, transcription, DNA-dependent, virus-host interaction Prp19 complex, cell surface, clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane, cytosol, extracellular vesicular exosome, intracellular, melanosome, nucleolus, nucleus, plasma membrane, ribonucleoprotein complex, spliceosomal complex ATP binding, ATPase activity, coupled, protein binding, unfolded protein binding Human UniProtKB:P25686-2 HSPA9 HPA UniProtKB {GO:0042645=PMID:18063578, GO:0005515=PMID:22726440, GO:0043066=PMID:16130169, GO:0009986=PMID:12493773, GO:0006626=Reactome:REACT_118595, GO:0005730=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0005739=GO_REF:0000052, GO:0005737=PMID:7684501, GO:0006457=GO_REF:0000002, GO:0006611=GO_REF:0000019, GO:0051082=PMID:16130169, GO:0019899=GO_REF:0000019, GO:0044267=Reactome:REACT_17015} P38646 Stress-70 protein, mitochondrial protein 20080205 {GO:0042645=IDA, GO:0005515=IPI, GO:0043066=TAS, GO:0009986=IDA, GO:0006626=TAS, GO:0005730=IEA, GO:0005524=IEA, GO:0005739=IDA, GO:0005737=TAS, GO:0006457=IEA, GO:0006611=IEA, GO:0051082=TAS, GO:0019899=IEA, GO:0044267=TAS} cellular protein metabolic process, negative regulation of apoptotic process, protein export from nucleus, protein folding, protein targeting to mitochondrion cell surface, cytoplasm, mitochondrial nucleoid, mitochondrion, nucleolus ATP binding, enzyme binding, protein binding, unfolded protein binding Human HSPB1 BHF-UCL UniProtKB {GO:0006986=PMID:1560006, GO:0005515=PMID:21575178, GO:0008219=GO_REF:0000037, GO:0010467=Reactome:REACT_71, GO:0043130=GO_REF:0000024, GO:0030018=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0032731=GO_REF:0000024, GO:0006928=PMID:16130169, GO:0005634=PMID:19464326, GO:0005829=Reactome:REACT_25315, GO:0005737=PMID:19464326, GO:0005080=GO_REF:0000024, GO:0005856=PMID:16130169, GO:0043122=GO_REF:0000024, GO:0000502=GO_REF:0000024, GO:0043066=GO_REF:0000024, GO:0009986=PMID:12493773, GO:0019901=PMID:8774846, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0042535=GO_REF:0000024, GO:0005819=GO_REF:0000039, GO:0009615=PMID:16548883, GO:0006446=PMID:10859165, GO:0008426=GO_REF:0000024, GO:0006469=GO_REF:0000024} P04792 Heat shock protein beta-1 protein 20120102 {GO:0006986=NAS, GO:0005515=IPI, GO:0008219=IEA, GO:0010467=TAS, GO:0043130=ISS, GO:0030018=IEA, GO:0005886=IEA, GO:0032731=ISS, GO:0006928=TAS, GO:0005634=IDA, GO:0005829=TAS, GO:0005737=IDA, GO:0005080=ISS, GO:0005856=TAS, GO:0043122=ISS, GO:0000502=ISS, GO:0043066=ISS, GO:0009986=IDA, GO:0019901=IPI, GO:0016070=TAS, GO:0016071=TAS, GO:0042535=ISS, GO:0005819=IEA, GO:0009615=IEP, GO:0006446=TAS, GO:0008426=ISS, GO:0006469=ISS} RNA metabolic process, cell death, cellular component movement, gene expression, mRNA metabolic process, negative regulation of apoptotic process, negative regulation of protein kinase activity, positive regulation of interleukin-1 beta production, positive regulation of tumor necrosis factor biosynthetic process, regulation of I-kappaB kinase/NF-kappaB cascade, regulation of translational initiation, response to unfolded protein, response to virus Z disc, cell surface, cytoplasm, cytoskeleton, cytosol, nucleus, plasma membrane, proteasome complex, spindle protein binding, protein kinase C binding, protein kinase C inhibitor activity, protein kinase binding, ubiquitin binding Human UniProtKB:P14602 HSPB11 ENSEMBL UniProtKB {GO:0005929=GO_REF:0000019, GO:0006950=GO_REF:0000037, GO:0030992=GO_REF:0000019, GO:0007155=GO_REF:0000002} Q9Y547 Heat shock protein beta-11 protein 20130413 {GO:0005929=IEA, GO:0006950=IEA, GO:0030992=IEA, GO:0007155=IEA} cell adhesion, response to stress cilium, intraflagellar transport particle B Human Ensembl:ENSMUSP00000048810 HSPB2 GOC UniProtKB {GO:0005515=PMID:14594798, GO:0006986=PMID:9344664, GO:0005737=GO_REF:0000052, GO:0009408=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0043085=PMID:9490724, GO:0008047=PMID:9490724, GO:0005829=PMID:9490724, GO:0007525=GO_REF:0000019} Q16082 Heat shock protein beta-2 protein 20130413 {GO:0005515=IPI, GO:0006986=NAS, GO:0005737=IDA, GO:0009408=IEA, GO:0005634=IDA, GO:0043085=TAS, GO:0008047=TAS, GO:0005829=TAS, GO:0007525=IEA} positive regulation of catalytic activity, response to heat, response to unfolded protein, somatic muscle development cytoplasm, cytosol, nucleus enzyme activator activity, protein binding Human HSPB3 PINC UniProtKB {GO:0006986=PMID:9858786, GO:0008219=GO_REF:0000037, GO:0005737=PMID:19464326, GO:0005634=PMID:19464326} Q12988 Heat shock protein beta-3 protein 20040806 {GO:0006986=TAS, GO:0008219=IEA, GO:0005737=IDA, GO:0005634=IDA} cell death, response to unfolded protein cytoplasm, nucleus Human HSPB6 IntAct UniProtKB {GO:0005515=PMID:16225851, GO:0005737=PMID:19464326, GO:0005212=GO_REF:0000002, GO:0006950=GO_REF:0000037, GO:0005634=PMID:19464326, GO:0042803=GO_REF:0000024} O14558 Heat shock protein beta-6 protein 20130415 {GO:0005515=IPI, GO:0005737=IDA, GO:0005212=IEA, GO:0006950=IEA, GO:0005634=IDA, GO:0042803=ISS} response to stress cytoplasm, nucleus protein binding, protein homodimerization activity, structural constituent of eye lens Human UniProtKB:Q9UJY1 HSPB7 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0006986=PMID:10593960, GO:0005739=GO_REF:0000019, GO:0005737=PMID:19464326, GO:0015030=GO_REF:0000039, GO:0008016=PMID:10593960, GO:0006950=GO_REF:0000038, GO:0005634=PMID:19464326, GO:0008022=PMID:10593960} Q9UBY9 Heat shock protein beta-7 protein 20130415 {GO:0005515=IPI, GO:0006986=TAS, GO:0005739=IEA, GO:0005737=IDA, GO:0015030=IEA, GO:0008016=TAS, GO:0006950=IEA, GO:0005634=IDA, GO:0008022=TAS} regulation of heart contraction, response to stress, response to unfolded protein Cajal body, cytoplasm, mitochondrion, nucleus protein C-terminus binding, protein binding Human UniProtKB:Q9UJY1 HSPB8 IntAct UniProtKB {GO:0005622=GO_REF:0000054, GO:0005515=PMID:16225851, GO:0008150=GO_REF:0000015, GO:0008219=GO_REF:0000037, GO:0005737=PMID:19464326, GO:0004672=PMID:14985082, GO:0006950=GO_REF:0000037, GO:0005634=PMID:19464326, GO:0042802=PMID:14594798} Q9UJY1 Heat shock protein beta-8 protein 20130415 {GO:0005622=IDA, GO:0005515=IPI, GO:0008150=ND, GO:0008219=IEA, GO:0005737=IDA, GO:0004672=IDA, GO:0006950=IEA, GO:0005634=IDA, GO:0042802=IPI} biological_process, cell death, response to stress cytoplasm, intracellular, nucleus identical protein binding, protein binding, protein kinase activity Human UniProtKB:Q9UJY1 HSPB9 IntAct UniProtKB {GO:0005515=PMID:15503857, GO:0005737=PMID:19464326, GO:0006950=GO_REF:0000037, GO:0005634=PMID:19464326} Q9BQS6 Heat shock protein beta-9 protein 20130415 {GO:0005515=IPI, GO:0005737=IDA, GO:0006950=IEA, GO:0005634=IDA} response to stress cytoplasm, nucleus protein binding Human UniProtKB:P63172 HSPBAP1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q96EW2 HSPB1-associated protein 1 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 HSPBP1 GOC UniProtKB {GO:0005515=PMID:16713569, GO:0004857=PMID:9830037, GO:0006457=PMID:9830037, GO:0032436=PMID:16831871, GO:0031398=PMID:16831871, GO:0043086=PMID:9830037} Q9NZL4 Hsp70-binding protein 1 protein 20130413 {GO:0005515=IPI, GO:0004857=TAS, GO:0006457=TAS, GO:0032436=IDA, GO:0031398=IDA, GO:0043086=TAS} negative regulation of catalytic activity, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of protein ubiquitination, protein folding enzyme inhibitor activity, protein binding Human HSPD1 GOC UniProtKB {GO:0005515=PMID:17823127, GO:0032755=PMID:16148103, GO:0006986=PMID:11050098, GO:0043498=PMID:11807771, GO:0043032=PMID:17164250, GO:0048291=PMID:16148103, GO:0003688=GO_REF:0000024, GO:0005615=PMID:18229457, GO:0042026=PMID:11050098, GO:0051604=GO_REF:0000024, GO:0044459=GO_REF:0000019, GO:0003697=GO_REF:0000024, GO:0006458=GO_REF:0000024, GO:0002755=PMID:16148103, GO:0005759=PMID:17823127, GO:0002842=PMID:10663613, GO:0032729=GO_REF:0000024, GO:0046696=PMID:17164250, GO:0002368=PMID:16148103, GO:0019907=PMID:11445587, GO:0009986=PMID:10663613, GO:0032727=PMID:17164250, GO:0006950=GO_REF:0000038, GO:0042113=PMID:16148103, GO:0042110=PMID:18256040, GO:0050870=GO_REF:0000024, GO:0051082=GO_REF:0000024, GO:0044267=GO_REF:0000002, GO:0006200=GO_REF:0000024, GO:0032733=PMID:16148103, GO:0030135=PMID:11807771, GO:0051087=PMID:10205158, GO:0005743=GO_REF:0000024, GO:0032735=PMID:17164250, GO:0005829=PMID:17823127, GO:0005739=GO_REF:0000052, GO:0002039=PMID:18086682, GO:0042100=PMID:16148103, GO:0030141=GO_REF:0000024, GO:0051131=GO_REF:0000024, GO:0016887=GO_REF:0000024, GO:0043066=PMID:17823127, GO:0043065=PMID:17823127, GO:0006919=PMID:17823127, GO:0050821=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0001530=PMID:17164250, GO:0005905=PMID:11807771, GO:0019048=GO_REF:0000037, GO:0005769=PMID:11807771} P10809 60 kDa heat shock protein, mitochondrial protein 20130413 {GO:0005515=IPI, GO:0032755=IDA, GO:0006986=IDA, GO:0043498=IDA, GO:0043032=IDA, GO:0048291=IDA, GO:0003688=ISS, GO:0005615=IDA, GO:0042026=IDA, GO:0051604=ISS, GO:0044459=IEA, GO:0003697=ISS, GO:0006458=ISS, GO:0002755=IDA, GO:0005759=TAS, GO:0002842=IDA, GO:0032729=ISS, GO:0046696=IDA, GO:0002368=IDA, GO:0019907=IDA, GO:0009986=IDA, GO:0032727=IDA, GO:0006950=IEA, GO:0042113=IDA, GO:0042110=IDA, GO:0050870=ISS, GO:0051082=ISS, GO:0044267=IEA, GO:0006200=ISS, GO:0032733=IDA, GO:0030135=IDA, GO:0051087=IPI, GO:0005743=ISS, GO:0032735=IDA, GO:0005829=IDA, GO:0005739=IDA, GO:0002039=IPI, GO:0042100=IDA, GO:0030141=ISS, GO:0051131=ISS, GO:0016887=ISS, GO:0043066=IMP, GO:0043065=IMP, GO:0006919=IDA, GO:0050821=ISS, GO:0005524=IEA, GO:0001530=IDA, GO:0005905=IDA, GO:0019048=IEA, GO:0005769=IDA} 'de novo' protein folding, ATP catabolic process, B cell activation, B cell cytokine production, B cell proliferation, MyD88-dependent toll-like receptor signaling pathway, T cell activation, activation of cysteine-type endopeptidase activity involved in apoptotic process, cellular protein metabolic process, chaperone-mediated protein complex assembly, isotype switching to IgG isotypes, negative regulation of apoptotic process, positive regulation of T cell activation, positive regulation of T cell mediated immune response to tumor cell, positive regulation of apoptotic process, positive regulation of interferon-alpha production, positive regulation of interferon-gamma production, positive regulation of interleukin-10 production, positive regulation of interleukin-12 production, positive regulation of interleukin-6 production, positive regulation of macrophage activation, protein maturation, protein refolding, protein stabilization, response to stress, response to unfolded protein, virus-host interaction cell surface, coated pit, coated vesicle, cyclin-dependent protein kinase activating kinase holoenzyme complex, cytosol, early endosome, extracellular space, lipopolysaccharide receptor complex, mitochondrial inner membrane, mitochondrial matrix, mitochondrion, plasma membrane part, secretory granule ATP binding, ATPase activity, DNA replication origin binding, cell surface binding, chaperone binding, lipopolysaccharide binding, p53 binding, protein binding, single-stranded DNA binding, unfolded protein binding Human UniProtKB:P19882 HSPE1 IntAct UniProtKB {GO:0006986=PMID:7698325, GO:0005515=PMID:18319262, GO:0005739=GO_REF:0000024, GO:0005737=GO_REF:0000002, GO:0006919=PMID:10205158, GO:0006457=GO_REF:0000002, GO:0005759=GO_REF:0000039, GO:0051087=GO_REF:0000024, GO:0006950=GO_REF:0000038, GO:0051082=PMID:12483302, GO:0005524=GO_REF:0000002} P61604 10 kDa heat shock protein, mitochondrial protein 20130415 {GO:0006986=TAS, GO:0005515=IPI, GO:0005739=ISS, GO:0005737=IEA, GO:0006919=NAS, GO:0006457=IEA, GO:0005759=IEA, GO:0051087=ISS, GO:0006950=IEA, GO:0051082=NAS, GO:0005524=IEA} activation of cysteine-type endopeptidase activity involved in apoptotic process, protein folding, response to stress, response to unfolded protein cytoplasm, mitochondrial matrix, mitochondrion ATP binding, chaperone binding, protein binding, unfolded protein binding Human UniProtKB:P49789 HSPG2 BHF-UCL UniProtKB {GO:0005515=PMID:11956183, GO:0006629=Reactome:REACT_602, GO:0005886=Reactome:REACT_160272, GO:0007603=Reactome:REACT_160125, GO:0048704=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0008104=GO_REF:0000019, GO:0002062=GO_REF:0000019, GO:0030198=GO_REF:0000019, GO:0060351=GO_REF:0000019, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408, GO:0043202=Reactome:REACT_121392, GO:0005796=Reactome:REACT_121320, GO:0005975=Reactome:REACT_474, GO:0005605=GO_REF:0000019, GO:0006027=Reactome:REACT_120752, GO:0005576=Reactome:REACT_75905, GO:0001525=GO_REF:0000037, GO:0008022=PMID:12604605, GO:0001523=Reactome:REACT_24968, GO:0006024=Reactome:REACT_121248, GO:0031012=PMID:22261194, GO:0048738=GO_REF:0000019, GO:0001958=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0042157=Reactome:REACT_6841} P98160 Basement membrane-specific heparan sulfate proteoglycan core protein protein 20120228 {GO:0005515=IPI, GO:0006629=TAS, GO:0005886=TAS, GO:0007603=TAS, GO:0048704=IEA, GO:0044281=TAS, GO:0046872=IEA, GO:0008104=IEA, GO:0002062=IEA, GO:0030198=IEA, GO:0060351=IEA, GO:0030204=TAS, GO:0030203=TAS, GO:0043202=TAS, GO:0005796=TAS, GO:0005975=TAS, GO:0005605=IEA, GO:0006027=TAS, GO:0005576=TAS, GO:0001525=IEA, GO:0008022=IPI, GO:0001523=TAS, GO:0006024=TAS, GO:0031012=ISS, GO:0048738=IEA, GO:0001958=IEA, GO:0007420=IEA, GO:0042157=TAS} angiogenesis, brain development, carbohydrate metabolic process, cardiac muscle tissue development, cartilage development involved in endochondral bone morphogenesis, chondrocyte differentiation, chondroitin sulfate metabolic process, embryonic skeletal system morphogenesis, endochondral ossification, extracellular matrix organization, glycosaminoglycan biosynthetic process, glycosaminoglycan catabolic process, glycosaminoglycan metabolic process, lipid metabolic process, lipoprotein metabolic process, phototransduction, visible light, protein localization, retinoid metabolic process, small molecule metabolic process Golgi lumen, basal lamina, extracellular matrix, extracellular region, lysosomal lumen, plasma membrane metal ion binding, protein C-terminus binding, protein binding colocalizes_with Human UniProtKB:F1SU03 HSPH1 HPA UniProtKB {GO:0006986=PMID:9931472, GO:0005737=GO_REF:0000052, GO:0045345=PMID:12952910, GO:0043014=GO_REF:0000019, GO:0005874=GO_REF:0000019, GO:0051135=PMID:12952910, GO:0051085=GO_REF:0000019, GO:0006950=GO_REF:0000038, GO:0005730=GO_REF:0000052, GO:0005576=PMID:12952910, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037} Q92598 Heat shock protein 105 kDa protein 20111111 {GO:0006986=TAS, GO:0005737=IDA, GO:0045345=TAS, GO:0043014=IEA, GO:0005874=IEA, GO:0051135=TAS, GO:0051085=IEA, GO:0006950=IEA, GO:0005730=IDA, GO:0005576=TAS, GO:0005634=IDA, GO:0005524=IEA} chaperone mediated protein folding requiring cofactor, positive regulation of MHC class I biosynthetic process, positive regulation of NK T cell activation, response to stress, response to unfolded protein cytoplasm, extracellular region, microtubule, nucleolus, nucleus ATP binding, alpha-tubulin binding Human HTATIP2 HPA UniProtKB {GO:0005515=PMID:15282309, GO:0043066=PMID:10611237, GO:0006357=PMID:9482853, GO:0051170=PMID:15282309, GO:0003713=PMID:9482853, GO:0006915=GO_REF:0000037, GO:0045765=PMID:11313954, GO:0005634=PMID:9482853, GO:0042981=PMID:9174052, GO:0006917=PMID:9174052, GO:0001525=GO_REF:0000037, GO:0005635=PMID:15282309, GO:0030154=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0019048=GO_REF:0000037, GO:0016491=GO_REF:0000037} Q9BUP3 Oxidoreductase HTATIP2 protein 20101115 {GO:0005515=IPI, GO:0043066=TAS, GO:0006357=TAS, GO:0051170=IDA, GO:0003713=TAS, GO:0006915=IEA, GO:0045765=IDA, GO:0005634=TAS, GO:0042981=IDA, GO:0006917=TAS, GO:0001525=IEA, GO:0005635=IDA, GO:0030154=IEA, GO:0005737=IDA, GO:0019048=IEA, GO:0016491=IEA} angiogenesis, apoptotic process, cell differentiation, induction of apoptosis, negative regulation of apoptotic process, nuclear import, regulation of angiogenesis, regulation of apoptotic process, regulation of transcription from RNA polymerase II promoter, virus-host interaction cytoplasm, nuclear envelope, nucleus oxidoreductase activity, protein binding, transcription coactivator activity Human HTATSF1 HPA UniProtKB {GO:0006357=PMID:10454543, GO:0000166=GO_REF:0000002, GO:0032784=PMID:10454543, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0019079=PMID:10454543, GO:0006351=GO_REF:0000037} Q5H919 HIV Tat-specific factor 1 protein 20080818 {GO:0006357=TAS, GO:0000166=IEA, GO:0032784=TAS, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0019079=TAS, GO:0006351=IEA} regulation of DNA-dependent transcription, elongation, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent, viral genome replication nucleolus, nucleus RNA binding, nucleic acid binding, nucleotide binding NOT Human HTN1 IntAct UniProtKB {GO:0005515=PMID:16203048, GO:0050832=GO_REF:0000037, GO:0031640=GO_REF:0000037, GO:0005576=PMID:3286634, GO:0031214=GO_REF:0000037, GO:0042742=PMID:3286634} P15515 Histatin-1 protein 20130415 {GO:0005515=IPI, GO:0050832=IEA, GO:0031640=IEA, GO:0005576=NAS, GO:0031214=IEA, GO:0042742=NAS} biomineral tissue development, defense response to bacterium, defense response to fungus, killing of cells of other organism extracellular region protein binding Human UniProtKB:Q8TAX7 HTN3 UniProtKB UniProtKB {GO:0050832=GO_REF:0000037, GO:0031640=GO_REF:0000037, GO:0005576=PMID:3286634, GO:0031214=GO_REF:0000037, GO:0042742=PMID:3286634, GO:0046872=GO_REF:0000037} P15516 Histatin-3 protein 20040129 {GO:0050832=IEA, GO:0031640=IEA, GO:0005576=NAS, GO:0031214=IEA, GO:0042742=NAS, GO:0046872=IEA} biomineral tissue development, defense response to bacterium, defense response to fungus, killing of cells of other organism extracellular region metal ion binding Human HTR1A GOC UniProtKB {GO:0008284=PMID:1330092, GO:0005886=Reactome:REACT_22289, GO:0008283=GO_REF:0000002, GO:0046883=GO_REF:0000002, GO:0042221=GO_REF:0000002, GO:0007210=PMID:9736659, GO:0004993=GO_REF:0000019, GO:0007186=PMID:1330092, GO:0005887=GO_REF:0000002, GO:0050795=GO_REF:0000002, GO:0042310=GO_REF:0000002, GO:0007610=GO_REF:0000002, GO:0030815=GO_REF:0000002, GO:0097458=GO_REF:0000002} P08908 5-hydroxytryptamine receptor 1A protein 20130413 {GO:0008284=TAS, GO:0005886=TAS, GO:0008283=IEA, GO:0046883=IEA, GO:0042221=IEA, GO:0007210=TAS, GO:0004993=IEA, GO:0007186=TAS, GO:0005887=IEA, GO:0050795=IEA, GO:0042310=IEA, GO:0007610=IEA, GO:0030815=IEA, GO:0097458=IEA} G-protein coupled receptor signaling pathway, behavior, cell proliferation, negative regulation of cAMP metabolic process, positive regulation of cell proliferation, regulation of behavior, regulation of hormone secretion, response to chemical stimulus, serotonin receptor signaling pathway, vasoconstriction integral to plasma membrane, neuron part, plasma membrane serotonin receptor activity Human HTR1B Reactome UniProtKB {GO:0005886=Reactome:REACT_22289, GO:0030818=PMID:8882600, GO:0051967=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0051385=GO_REF:0000019, GO:0007268=GO_REF:0000019, GO:0051378=GO_REF:0000019, GO:0042220=GO_REF:0000019, GO:0002031=GO_REF:0000019, GO:0007205=GO_REF:0000019, GO:0014059=GO_REF:0000019, GO:0004993=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0071502=GO_REF:0000019, GO:0007186=PMID:1315531, GO:0046849=GO_REF:0000019, GO:0007187=PMID:1559993, GO:0050795=GO_REF:0000002, GO:0042756=GO_REF:0000019, GO:0005887=GO_REF:0000002, GO:0008144=GO_REF:0000019, GO:0042310=GO_REF:0000002, GO:0032229=GO_REF:0000019} P28222 5-hydroxytryptamine receptor 1B protein 20090212 {GO:0005886=TAS, GO:0030818=IDA, GO:0051967=IEA, GO:0045471=IEA, GO:0042493=IEA, GO:0051385=IEA, GO:0007268=IEA, GO:0051378=IEA, GO:0042220=IEA, GO:0002031=IEA, GO:0007205=IEA, GO:0014059=IEA, GO:0004993=IEA, GO:0005737=IEA, GO:0071502=IEA, GO:0007186=TAS, GO:0046849=IEA, GO:0007187=TAS, GO:0050795=IEA, GO:0042756=IEA, GO:0005887=IEA, GO:0008144=IEA, GO:0042310=IEA, GO:0032229=IEA} G-protein coupled receptor internalization, G-protein coupled receptor signaling pathway, G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, bone remodeling, cellular response to temperature stimulus, drinking behavior, negative regulation of cAMP biosynthetic process, negative regulation of synaptic transmission, GABAergic, negative regulation of synaptic transmission, glutamatergic, protein kinase C-activating G-protein coupled receptor signaling pathway, regulation of behavior, regulation of dopamine secretion, response to cocaine, response to drug, response to ethanol, response to mineralocorticoid stimulus, synaptic transmission, vasoconstriction cytoplasm, integral to plasma membrane, plasma membrane drug binding, serotonin binding, serotonin receptor activity Human HTR1D Reactome UniProtKB {GO:0005886=Reactome:REACT_22289, GO:0007268=GO_REF:0000002, GO:0009636=GO_REF:0000019, GO:0051378=GO_REF:0000019, GO:0014827=PMID:9186750, GO:0040012=GO_REF:0000002, GO:0004993=GO_REF:0000019, GO:0005887=GO_REF:0000002, GO:0050795=GO_REF:0000002, GO:0007187=PMID:1565658, GO:0042310=GO_REF:0000002, GO:0007610=GO_REF:0000002, GO:0030815=GO_REF:0000002} P28221 5-hydroxytryptamine receptor 1D protein 20090212 {GO:0005886=TAS, GO:0007268=IEA, GO:0009636=IEA, GO:0051378=IEA, GO:0014827=IMP, GO:0040012=IEA, GO:0004993=IEA, GO:0005887=IEA, GO:0050795=IEA, GO:0007187=TAS, GO:0042310=IEA, GO:0007610=IEA, GO:0030815=IEA} G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, behavior, intestine smooth muscle contraction, negative regulation of cAMP metabolic process, regulation of behavior, regulation of locomotion, response to toxic substance, synaptic transmission, vasoconstriction integral to plasma membrane, plasma membrane serotonin binding, serotonin receptor activity Human HTR1E GOC UniProtKB {GO:0004993=PMID:1608964, GO:0005886=Reactome:REACT_22289, GO:0007186=PMID:1608964, GO:0007187=PMID:1733778, GO:0004930=PMID:1733778, GO:0005887=GO_REF:0000002, GO:0007610=GO_REF:0000002, GO:0007268=GO_REF:0000002, GO:0030815=GO_REF:0000002, GO:0051378=PMID:1608964, GO:0007210=PMID:1608964} P28566 5-hydroxytryptamine receptor 1E protein 20130413 {GO:0004993=IDA, GO:0005886=TAS, GO:0007186=TAS, GO:0007187=TAS, GO:0004930=TAS, GO:0005887=IEA, GO:0007610=IEA, GO:0007268=IEA, GO:0030815=IEA, GO:0051378=IDA, GO:0007210=IDA} G-protein coupled receptor signaling pathway, G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, behavior, negative regulation of cAMP metabolic process, serotonin receptor signaling pathway, synaptic transmission integral to plasma membrane, plasma membrane G-protein coupled receptor activity, serotonin binding, serotonin receptor activity Human HTR1F GOC UniProtKB {GO:0004993=PMID:8380639, GO:0005886=Reactome:REACT_22289, GO:0007187=PMID:8380639, GO:0005887=GO_REF:0000002, GO:0007610=GO_REF:0000002, GO:0007268=GO_REF:0000002, GO:0030815=GO_REF:0000002, GO:0051378=PMID:8380639, GO:0007210=PMID:8380639} P30939 5-hydroxytryptamine receptor 1F protein 20130413 {GO:0004993=IDA, GO:0005886=TAS, GO:0007187=TAS, GO:0005887=IEA, GO:0007610=IEA, GO:0007268=IEA, GO:0030815=IEA, GO:0051378=IDA, GO:0007210=IDA} G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, behavior, negative regulation of cAMP metabolic process, serotonin receptor signaling pathway, synaptic transmission integral to plasma membrane, plasma membrane serotonin binding, serotonin receptor activity Human HTR2A Reactome UniProtKB {GO:0008219=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0001659=GO_REF:0000019, GO:0005886=Reactome:REACT_22436, GO:0043267=GO_REF:0000019, GO:0007268=PMID:9109547, GO:0051378=PMID:7582481, GO:0032403=GO_REF:0000019, GO:0014059=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0006939=GO_REF:0000002, GO:0001965=GO_REF:0000019, GO:0004993=PMID:7582481, GO:0050880=GO_REF:0000002, GO:0045907=GO_REF:0000019, GO:0043198=GO_REF:0000019, GO:0043406=GO_REF:0000019, GO:0008144=PMID:15831837, GO:0071886=PMID:19057895, GO:0007613=GO_REF:0000019, GO:0070371=PMID:19057895, GO:0051209=PMID:18703043, GO:0006661=PMID:19057895, GO:0042493=PMID:15862800, GO:0051967=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0006950=GO_REF:0000019, GO:0046883=GO_REF:0000002, GO:0030431=GO_REF:0000019, GO:0014065=PMID:16517693, GO:0007210=PMID:18703043, GO:0019233=GO_REF:0000019, GO:1900482=GO_REF:0000002, GO:0004435=PMID:16517693, GO:0005887=GO_REF:0000002, GO:0050795=GO_REF:0000002, GO:0007208=GO_REF:0000019, GO:0032962=GO_REF:0000002} P28223 5-hydroxytryptamine receptor 2A protein 20090212 {GO:0008219=IEA, GO:0008284=IEA, GO:0001659=IEA, GO:0005886=TAS, GO:0043267=IEA, GO:0007268=TAS, GO:0051378=IDA, GO:0032403=IEA, GO:0014059=IEA, GO:0005829=IEA, GO:0006939=IEA, GO:0001965=IEA, GO:0004993=IDA, GO:0050880=IEA, GO:0045907=IEA, GO:0043198=IEA, GO:0043406=IEA, GO:0008144=IDA, GO:0071886=IDA, GO:0007613=IEA, GO:0070371=IMP, GO:0051209=IMP, GO:0006661=IMP, GO:0042493=IDA, GO:0051967=IEA, GO:0007568=IEA, GO:0006950=IEA, GO:0046883=IEA, GO:0030431=IEA, GO:0014065=IMP, GO:0007210=IMP, GO:0019233=IEA, GO:1900482=IEA, GO:0004435=IMP, GO:0005887=IEA, GO:0050795=IEA, GO:0007208=IEA, GO:0032962=IEA} ERK1 and ERK2 cascade, aging, cell death, memory, negative regulation of potassium ion transport, negative regulation of synaptic transmission, glutamatergic, phosphatidylinositol 3-kinase cascade, phosphatidylinositol biosynthetic process, phospholipase C-activating serotonin receptor signaling pathway, positive regulation of MAP kinase activity, positive regulation of cell proliferation, positive regulation of diacylglycerol biosynthetic process, positive regulation of inositol trisphosphate biosynthetic process, positive regulation of vasoconstriction, regulation of behavior, regulation of blood vessel size, regulation of dopamine secretion, regulation of hormone secretion, release of sequestered calcium ion into cytosol, response to drug, response to stress, sensory perception of pain, serotonin receptor signaling pathway, sleep, smooth muscle contraction, synaptic transmission, temperature homeostasis cytosol, dendritic shaft, integral to plasma membrane, plasma membrane 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding, G-protein alpha-subunit binding, drug binding, phosphatidylinositol phospholipase C activity, protein complex binding, serotonin binding, serotonin receptor activity Human HTR2B GOC UniProtKB {GO:0008284=PMID:15925089, GO:0019722=PMID:8882600, GO:0005886=Reactome:REACT_22436, GO:0001755=GO_REF:0000024, GO:0050715=GO_REF:0000024, GO:0001819=PMID:19023134, GO:0051378=PMID:7582481, GO:0048598=GO_REF:0000024, GO:0007205=GO_REF:0000024, GO:0003300=GO_REF:0000024, GO:0001965=PMID:15625277, GO:0005737=PMID:15925089, GO:0004993=PMID:7582481, GO:0043406=PMID:15625277, GO:0014033=GO_REF:0000024, GO:0008144=PMID:15831837, GO:0042310=PMID:15625277, GO:0060548=PMID:20099302, GO:0071277=PMID:19057895, GO:0007610=GO_REF:0000002, GO:0051781=GO_REF:0000024, GO:0070371=PMID:19057895, GO:0043123=PMID:12761501, GO:0005262=PMID:8882600, GO:0043066=GO_REF:0000024, GO:0051209=PMID:8882600, GO:0006661=PMID:19057895, GO:0042493=PMID:15862800, GO:0014065=PMID:16517693, GO:0014827=PMID:9186750, GO:0002031=PMID:15625277, GO:0070528=PMID:20099302, GO:0007210=PMID:18703043, GO:0005099=GO_REF:0000024, GO:0016310=PMID:19308295, GO:0003007=GO_REF:0000024, GO:0071502=GO_REF:0000024, GO:0007186=PMID:15625277, GO:0001938=PMID:19308295, GO:1900482=GO_REF:0000002, GO:0051000=PMID:15625277, GO:0004435=PMID:16517693, GO:0050795=PMID:21179162, GO:0005887=GO_REF:0000002, GO:0006182=PMID:12970106, GO:0070588=PMID:8882600, GO:0010507=PMID:20099302, GO:0032962=GO_REF:0000002} P41595 5-hydroxytryptamine receptor 2B protein 20130413 {GO:0008284=IMP, GO:0019722=IMP, GO:0005886=TAS, GO:0001755=ISS, GO:0050715=ISS, GO:0001819=IDA, GO:0051378=IDA, GO:0048598=ISS, GO:0007205=ISS, GO:0003300=ISS, GO:0001965=IMP, GO:0005737=IDA, GO:0004993=IDA, GO:0043406=IDA, GO:0014033=ISS, GO:0008144=IDA, GO:0042310=IMP, GO:0060548=IMP, GO:0071277=IMP, GO:0007610=IEA, GO:0051781=ISS, GO:0070371=IMP, GO:0043123=IEP, GO:0005262=IMP, GO:0043066=ISS, GO:0051209=IMP, GO:0006661=IMP, GO:0042493=IDA, GO:0014065=IMP, GO:0014827=IMP, GO:0002031=IMP, GO:0070528=IMP, GO:0007210=IMP, GO:0005099=ISS, GO:0016310=IMP, GO:0003007=ISS, GO:0071502=ISS, GO:0007186=IMP, GO:0001938=IMP, GO:1900482=IEA, GO:0051000=IDA, GO:0004435=IMP, GO:0050795=IMP, GO:0005887=IEA, GO:0006182=IDA, GO:0070588=IMP, GO:0010507=IMP, GO:0032962=IEA} ERK1 and ERK2 cascade, G-protein coupled receptor internalization, G-protein coupled receptor signaling pathway, behavior, cGMP biosynthetic process, calcium ion transmembrane transport, calcium-mediated signaling, cardiac muscle hypertrophy, cellular response to calcium ion, cellular response to temperature stimulus, embryonic morphogenesis, heart morphogenesis, intestine smooth muscle contraction, negative regulation of apoptotic process, negative regulation of autophagy, negative regulation of cell death, neural crest cell differentiation, neural crest cell migration, phosphatidylinositol 3-kinase cascade, phosphatidylinositol biosynthetic process, phosphorylation, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of MAP kinase activity, positive regulation of cell division, positive regulation of cell proliferation, positive regulation of cytokine production, positive regulation of cytokine secretion, positive regulation of diacylglycerol biosynthetic process, positive regulation of endothelial cell proliferation, positive regulation of inositol trisphosphate biosynthetic process, positive regulation of nitric-oxide synthase activity, protein kinase C signaling cascade, protein kinase C-activating G-protein coupled receptor signaling pathway, regulation of behavior, release of sequestered calcium ion into cytosol, response to drug, serotonin receptor signaling pathway, vasoconstriction cytoplasm, integral to plasma membrane, plasma membrane G-protein alpha-subunit binding, Ras GTPase activator activity, calcium channel activity, drug binding, phosphatidylinositol phospholipase C activity, serotonin binding, serotonin receptor activity Human HTR2C Reactome UniProtKB {GO:0007631=GO_REF:0000002, GO:0051209=PMID:18703043, GO:0006661=PMID:19057895, GO:0005886=Reactome:REACT_22436, GO:0042493=PMID:18703043, GO:0007268=GO_REF:0000002, GO:0051378=PMID:7582481, GO:0019098=GO_REF:0000002, GO:0007210=PMID:18703043, GO:0004993=PMID:7582481, GO:1900482=GO_REF:0000002, GO:0004435=PMID:12970106, GO:0005887=GO_REF:0000002, GO:0006182=PMID:12970106, GO:0071886=PMID:19057895, GO:0008144=PMID:15831837, GO:0040013=GO_REF:0000002, GO:0042310=GO_REF:0000002, GO:0032962=GO_REF:0000002, GO:0070371=PMID:19057895} P28335 5-hydroxytryptamine receptor 2C protein 20090212 {GO:0007631=IEA, GO:0051209=IMP, GO:0006661=IMP, GO:0005886=TAS, GO:0042493=IDA, GO:0007268=IEA, GO:0051378=IDA, GO:0019098=IEA, GO:0007210=IMP, GO:0004993=IDA, GO:1900482=IEA, GO:0004435=IDA, GO:0005887=IEA, GO:0006182=IDA, GO:0071886=IDA, GO:0008144=IDA, GO:0040013=IEA, GO:0042310=IEA, GO:0032962=IEA, GO:0070371=IMP} ERK1 and ERK2 cascade, cGMP biosynthetic process, feeding behavior, negative regulation of locomotion, phosphatidylinositol biosynthetic process, positive regulation of diacylglycerol biosynthetic process, positive regulation of inositol trisphosphate biosynthetic process, release of sequestered calcium ion into cytosol, reproductive behavior, response to drug, serotonin receptor signaling pathway, synaptic transmission, vasoconstriction integral to plasma membrane, plasma membrane 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding, drug binding, phosphatidylinositol phospholipase C activity, serotonin binding, serotonin receptor activity Human HTR3A InterPro UniProtKB {GO:0005232=PMID:7565620, GO:0005230=GO_REF:0000029, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_25246, GO:0007586=PMID:7565620, GO:0007268=PMID:7565620, GO:0051378=PMID:7565620, GO:0055085=Reactome:REACT_15518, GO:0007210=PMID:7565620, GO:0004993=PMID:7565620, GO:0034220=Reactome:REACT_25387, GO:0005887=PMID:7565620, GO:0045211=GO_REF:0000002, GO:0006810=GO_REF:0000029, GO:0004872=PMID:9950429, GO:0016021=GO_REF:0000002, GO:0015276=GO_REF:0000002} Q9UEP2 5-hydroxytryptamine receptor 3A protein 20130413 {GO:0005232=TAS, GO:0005230=NAS, GO:0030054=IEA, GO:0005886=TAS, GO:0007586=TAS, GO:0007268=TAS, GO:0051378=IDA, GO:0055085=TAS, GO:0007210=IDA, GO:0004993=IDA, GO:0034220=TAS, GO:0005887=TAS, GO:0045211=IEA, GO:0006810=NAS, GO:0004872=TAS, GO:0016021=IEA, GO:0015276=IEA} digestion, ion transmembrane transport, serotonin receptor signaling pathway, synaptic transmission, transmembrane transport, transport cell junction, integral to membrane, integral to plasma membrane, plasma membrane, postsynaptic membrane extracellular ligand-gated ion channel activity, ligand-gated ion channel activity, receptor activity, serotonin binding, serotonin receptor activity, serotonin-activated cation-selective channel activity Human InterPro:IPR008132|InterPro:IPR008133 HTR3C Reactome UniProtKB {GO:0005230=GO_REF:0000002, GO:0034220=Reactome:REACT_25387, GO:0005886=Reactome:REACT_25246, GO:0045211=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_15518} Q8WXA8 5-hydroxytryptamine receptor 3C protein 20100923 {GO:0005230=IEA, GO:0034220=TAS, GO:0005886=TAS, GO:0045211=IEA, GO:0016021=IEA, GO:0055085=TAS} ion transmembrane transport, transmembrane transport integral to membrane, plasma membrane, postsynaptic membrane extracellular ligand-gated ion channel activity Human HTR4 GOC UniProtKB {GO:0008284=PMID:15925089, GO:0005886=Reactome:REACT_22268, GO:0007268=GO_REF:0000002, GO:0032098=GO_REF:0000002, GO:0007210=PMID:9603189, GO:0004993=PMID:16102731, GO:0005737=PMID:15925089, GO:0050890=GO_REF:0000002, GO:0016020=PMID:16102731, GO:0007186=PMID:9351641, GO:0007187=PMID:9603189, GO:0005887=GO_REF:0000002, GO:0030816=GO_REF:0000002, GO:0045761=GO_REF:0000002, GO:0004683=GO_REF:0000002, GO:0005768=GO_REF:0000039} Q13639 5-hydroxytryptamine receptor 4 protein 20130413 {GO:0008284=IMP, GO:0005886=TAS, GO:0007268=IEA, GO:0032098=IEA, GO:0007210=TAS, GO:0004993=IDA, GO:0005737=IDA, GO:0050890=IEA, GO:0016020=IDA, GO:0007186=TAS, GO:0007187=TAS, GO:0005887=IEA, GO:0030816=IEA, GO:0045761=IEA, GO:0004683=IEA, GO:0005768=IEA} G-protein coupled receptor signaling pathway, G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, cognition, positive regulation of cAMP metabolic process, positive regulation of cell proliferation, regulation of adenylate cyclase activity, regulation of appetite, serotonin receptor signaling pathway, synaptic transmission cytoplasm, endosome, integral to plasma membrane, membrane, plasma membrane calmodulin-dependent protein kinase activity, serotonin receptor activity Human HTR6 IntAct UniProtKB {GO:0005515=PMID:17189269, GO:0005886=Reactome:REACT_22268, GO:0042493=GO_REF:0000019, GO:0014050=GO_REF:0000019, GO:0046883=GO_REF:0000002, GO:0014053=GO_REF:0000019, GO:0007268=PMID:8522988, GO:0060291=GO_REF:0000019, GO:0014054=GO_REF:0000019, GO:0004969=PMID:8522988, GO:0030425=GO_REF:0000019, GO:0014058=GO_REF:0000019, GO:0004993=GO_REF:0000019, GO:0007187=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0005887=GO_REF:0000002, GO:0030816=GO_REF:0000002, GO:0007612=GO_REF:0000019, GO:0032355=GO_REF:0000019, GO:0033603=GO_REF:0000019} P50406 5-hydroxytryptamine receptor 6 protein 20130415 {GO:0005515=IPI, GO:0005886=TAS, GO:0042493=IEA, GO:0014050=IEA, GO:0046883=IEA, GO:0014053=IEA, GO:0007268=TAS, GO:0060291=IEA, GO:0014054=IEA, GO:0004969=TAS, GO:0030425=IEA, GO:0014058=IEA, GO:0004993=IEA, GO:0007187=IEA, GO:0007420=IEA, GO:0005887=IEA, GO:0030816=IEA, GO:0007612=IEA, GO:0032355=IEA, GO:0033603=IEA} G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, brain development, learning, long-term synaptic potentiation, negative regulation of acetylcholine secretion, negative regulation of gamma-aminobutyric acid secretion, negative regulation of glutamate secretion, positive regulation of cAMP metabolic process, positive regulation of dopamine secretion, positive regulation of gamma-aminobutyric acid secretion, regulation of hormone secretion, response to drug, response to estradiol stimulus, synaptic transmission dendrite, integral to plasma membrane, plasma membrane histamine receptor activity, protein binding, serotonin receptor activity Human UniProtKB:P06241 HTR7 InterPro UniProtKB {GO:0006939=GO_REF:0000002, GO:0004993=GO_REF:0000002, GO:0005886=Reactome:REACT_22268, GO:0007187=PMID:8226867, GO:0005887=GO_REF:0000002, GO:0008015=PMID:8226867, GO:0042310=GO_REF:0000002, GO:0030816=GO_REF:0000002, GO:0007623=GO_REF:0000002, GO:0007610=GO_REF:0000002, GO:0007268=GO_REF:0000002, GO:0007210=PMID:8226867} Q5VX04 5-hydroxytryptamine receptor 7 protein 20130413 {GO:0006939=IEA, GO:0004993=IEA, GO:0005886=TAS, GO:0007187=TAS, GO:0005887=IEA, GO:0008015=TAS, GO:0042310=IEA, GO:0030816=IEA, GO:0007623=IEA, GO:0007610=IEA, GO:0007268=IEA, GO:0007210=TAS} G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, behavior, blood circulation, circadian rhythm, positive regulation of cAMP metabolic process, serotonin receptor signaling pathway, smooth muscle contraction, synaptic transmission, vasoconstriction integral to plasma membrane, plasma membrane serotonin receptor activity Human InterPro:IPR001069 HTRA1 PINC UniProtKB {GO:0030514=GO_REF:0000019, GO:0004252=GO_REF:0000002, GO:0006508=GO_REF:0000024, GO:0008236=GO_REF:0000024, GO:0005615=PMID:9852107, GO:0001558=GO_REF:0000002, GO:0030512=GO_REF:0000019, GO:0005829=GO_REF:0000039, GO:0005520=GO_REF:0000002} Q92743 Serine protease HTRA1 protein 20030904 {GO:0030514=IEA, GO:0004252=IEA, GO:0006508=ISS, GO:0008236=ISS, GO:0005615=TAS, GO:0001558=IEA, GO:0030512=IEA, GO:0005829=IEA, GO:0005520=IEA} negative regulation of BMP signaling pathway, negative regulation of transforming growth factor beta receptor signaling pathway, proteolysis, regulation of cell growth cytosol, extracellular space insulin-like growth factor binding, serine-type endopeptidase activity, serine-type peptidase activity Human HTRA2 BHF-UCL UniProtKB {GO:0005515=PMID:20125124, GO:0035631=GO_REF:0000024, GO:0004252=PMID:10873535, GO:0005783=PMID:10995577, GO:0006672=GO_REF:0000019, GO:0005634=PMID:10971580, GO:0006923=PMID:18309324, GO:0005739=PMID:18309324, GO:0005758=PMID:15044455, GO:0048666=GO_REF:0000019, GO:0040014=GO_REF:0000019, GO:0006508=PMID:10873535, GO:0007628=GO_REF:0000019, GO:0060548=GO_REF:0000019, GO:0019742=GO_REF:0000019, GO:0031966=GO_REF:0000039, GO:0043065=PMID:20125124, GO:0006950=PMID:10971580, GO:0097194=PMID:18309324, GO:0009635=GO_REF:0000019, GO:2001244=PMID:20125124, GO:0097193=GO_REF:0000019, GO:0071363=PMID:20125124, GO:0005789=PMID:10644717, GO:0009898=GO_REF:0000024, GO:0008236=PMID:18309324, GO:0008233=PMID:11604410, GO:0051082=PMID:10644717, GO:0030900=GO_REF:0000019, GO:0007005=GO_REF:0000019} O43464 Serine protease HTRA2, mitochondrial protein 20110110 {GO:0005515=IPI, GO:0035631=ISS, GO:0004252=TAS, GO:0005783=NAS, GO:0006672=IEA, GO:0005634=TAS, GO:0006923=TAS, GO:0005739=TAS, GO:0005758=IDA, GO:0048666=IEA, GO:0040014=IEA, GO:0006508=TAS, GO:0007628=IEA, GO:0060548=IEA, GO:0019742=IEA, GO:0031966=IEA, GO:0043065=IMP, GO:0006950=TAS, GO:0097194=TAS, GO:0009635=IEA, GO:2001244=IMP, GO:0097193=IEA, GO:0071363=IMP, GO:0005789=TAS, GO:0009898=ISS, GO:0008236=TAS, GO:0008233=IDA, GO:0051082=NAS, GO:0030900=IEA, GO:0007005=IEA} adult walking behavior, cellular response to growth factor stimulus, ceramide metabolic process, cleavage of cytoskeletal proteins involved in execution phase of apoptosis, execution phase of apoptosis, forebrain development, intrinsic apoptotic signaling pathway, mitochondrion organization, negative regulation of cell death, neuron development, pentacyclic triterpenoid metabolic process, positive regulation of apoptotic process, positive regulation of intrinsic apoptotic signaling pathway, proteolysis, regulation of multicellular organism growth, response to herbicide, response to stress CD40 receptor complex, endoplasmic reticulum, endoplasmic reticulum membrane, internal side of plasma membrane, mitochondrial intermembrane space, mitochondrial membrane, mitochondrion, nucleus peptidase activity, protein binding, serine-type endopeptidase activity, serine-type peptidase activity, unfolded protein binding Human UniProtKB:Q9JIY5 HTRA3 UniProtKB UniProtKB {GO:0005515=PMID:22229724, GO:0030514=GO_REF:0000024, GO:0004252=GO_REF:0000002, GO:0006508=PMID:22229724, GO:0008236=PMID:22229724, GO:0005576=GO_REF:0000039, GO:0001558=GO_REF:0000002, GO:0030512=GO_REF:0000024, GO:0005520=GO_REF:0000002} P83110 Serine protease HTRA3 protein 20120413 {GO:0005515=IPI, GO:0030514=ISS, GO:0004252=IEA, GO:0006508=IDA, GO:0008236=IDA, GO:0005576=IEA, GO:0001558=IEA, GO:0030512=ISS, GO:0005520=IEA} negative regulation of BMP signaling pathway, negative regulation of transforming growth factor beta receptor signaling pathway, proteolysis, regulation of cell growth extracellular region insulin-like growth factor binding, protein binding, serine-type endopeptidase activity, serine-type peptidase activity Human UniProtKB:Q9D236 HTT HPA UniProtKB {GO:0005515=PMID:23275563, GO:0034452=PMID:18922795, GO:0000132=PMID:20696378, GO:0007283=GO_REF:0000019, GO:0006606=GO_REF:0000019, GO:0051402=GO_REF:0000019, GO:0043524=GO_REF:0000019, GO:0048167=GO_REF:0000019, GO:0047496=PMID:20515468, GO:0007030=PMID:20515468, GO:0005794=PMID:15837803, GO:0051938=GO_REF:0000019, GO:0006890=PMID:20515468, GO:0007569=GO_REF:0000019, GO:0048487=PMID:11870213, GO:0007212=GO_REF:0000019, GO:0006888=GO_REF:0000019, GO:0045505=PMID:20515468, GO:0043234=PMID:18922795, GO:0051592=GO_REF:0000019, GO:0019805=GO_REF:0000019, GO:0050809=GO_REF:0000019, GO:0008542=GO_REF:0000019, GO:0035176=GO_REF:0000019, GO:0042445=GO_REF:0000019, GO:0048341=GO_REF:0000019, GO:0008088=GO_REF:0000019, GO:0030073=GO_REF:0000019, GO:0008134=GO_REF:0000033, GO:0030424=PMID:7748555, GO:0005783=PMID:17704510, GO:0005634=GO_REF:0000052, GO:0048513=GO_REF:0000033, GO:0021988=GO_REF:0000019, GO:0019244=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0008340=GO_REF:0000019, GO:0055072=GO_REF:0000019, GO:0030425=PMID:7748555, GO:0034047=PMID:21562226, GO:0005829=PMID:20515468, GO:0002039=PMID:10823891, GO:0005737=GO_REF:0000052, GO:0048666=GO_REF:0000019, GO:0016197=GO_REF:0000019, GO:0021990=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0046825=PMID:15654337, GO:0030659=PMID:7748555, GO:0046902=GO_REF:0000019, GO:0005776=PMID:17704510, GO:0016234=GO_REF:0000019, GO:0005770=PMID:17704510, GO:0005730=GO_REF:0000052, GO:0051881=GO_REF:0000019, GO:0021756=GO_REF:0000019, GO:0000050=GO_REF:0000019, GO:0000052=GO_REF:0000019, GO:0007029=GO_REF:0000019} P42858 Huntingtin protein 20101115 {GO:0005515=IPI, GO:0034452=IPI, GO:0000132=IMP, GO:0007283=IEA, GO:0006606=IEA, GO:0051402=IEA, GO:0043524=IEA, GO:0048167=IEA, GO:0047496=IMP, GO:0007030=IMP, GO:0005794=IDA, GO:0051938=IEA, GO:0006890=IMP, GO:0007569=IEA, GO:0048487=IDA, GO:0007212=IEA, GO:0006888=IEA, GO:0045505=IDA, GO:0043234=IDA, GO:0051592=IEA, GO:0019805=IEA, GO:0050809=IEA, GO:0008542=IEA, GO:0035176=IEA, GO:0042445=IEA, GO:0048341=IEA, GO:0008088=IEA, GO:0030073=IEA, GO:0008134=IBA, GO:0030424=IDA, GO:0005783=IDA, GO:0005634=IDA, GO:0048513=IBA, GO:0021988=IEA, GO:0019244=IEA, GO:0009952=IEA, GO:0008340=IEA, GO:0055072=IEA, GO:0030425=IDA, GO:0034047=IMP, GO:0005829=IDA, GO:0002039=IPI, GO:0005737=IDA, GO:0048666=IEA, GO:0016197=IEA, GO:0021990=IEA, GO:0007626=IEA, GO:0046825=IMP, GO:0030659=IDA, GO:0046902=IEA, GO:0005776=IDA, GO:0016234=IEA, GO:0005770=IDA, GO:0005730=IDA, GO:0051881=IEA, GO:0021756=IEA, GO:0000050=IEA, GO:0000052=IEA, GO:0007029=IEA} ER to Golgi vesicle-mediated transport, Golgi organization, L-glutamate import, anterior/posterior pattern specification, axon cargo transport, cell aging, citrulline metabolic process, determination of adult lifespan, dopamine receptor signaling pathway, endoplasmic reticulum organization, endosomal transport, establishment of mitotic spindle orientation, hormone metabolic process, insulin secretion, iron ion homeostasis, lactate biosynthetic process from pyruvate, locomotory behavior, negative regulation of neuron apoptotic process, neural plate formation, neuron apoptotic process, neuron development, olfactory lobe development, organ development, paraxial mesoderm formation, protein import into nucleus, quinolinate biosynthetic process, regulation of mitochondrial membrane permeability, regulation of mitochondrial membrane potential, regulation of protein export from nucleus, regulation of protein phosphatase type 2A activity, regulation of synaptic plasticity, response to calcium ion, retrograde vesicle-mediated transport, Golgi to ER, social behavior, spermatogenesis, striatum development, urea cycle, vesicle transport along microtubule, visual learning Golgi apparatus, autophagic vacuole, axon, cytoplasm, cytoplasmic vesicle membrane, cytosol, dendrite, endoplasmic reticulum, inclusion body, late endosome, nucleolus, nucleus, protein complex beta-tubulin binding, diazepam binding, dynactin binding, dynein intermediate chain binding, p53 binding, protein binding, transcription factor binding Human HUNK PINC UniProtKB {GO:0007165=PMID:10662544, GO:0004674=GO_REF:0000037, GO:0007275=PMID:10662544, GO:0005524=GO_REF:0000037} P57058 Hormonally up-regulated neu tumor-associated kinase protein 20030904 {GO:0007165=TAS, GO:0004674=IEA, GO:0007275=TAS, GO:0005524=IEA} multicellular organismal development, signal transduction ATP binding, protein serine/threonine kinase activity Human HUS1 HPA UniProtKB {GO:0005515=PMID:19464297, GO:0030896=GO_REF:0000002, GO:0005794=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=PMID:10846170, GO:0009790=GO_REF:0000019, GO:0006974=PMID:9872989, GO:0071479=PMID:21659603, GO:0006260=Reactome:REACT_6769, GO:0006281=PMID:9872989, GO:0000724=GO_REF:0000019, GO:0000075=Reactome:REACT_1538, GO:0001932=GO_REF:0000019, GO:0006468=GO_REF:0000019, GO:0005654=Reactome:REACT_6729, GO:0000077=PMID:21659603, GO:0008156=GO_REF:0000019, GO:0009411=GO_REF:0000019} O60921 Checkpoint protein HUS1 protein 20101115 {GO:0005515=IPI, GO:0030896=IEA, GO:0005794=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0009790=IEA, GO:0006974=TAS, GO:0071479=IDA, GO:0006260=TAS, GO:0006281=TAS, GO:0000724=IEA, GO:0000075=TAS, GO:0001932=IEA, GO:0006468=IEA, GO:0005654=TAS, GO:0000077=IMP, GO:0008156=IEA, GO:0009411=IEA} DNA damage checkpoint, DNA repair, DNA replication, cell cycle checkpoint, cellular response to ionizing radiation, double-strand break repair via homologous recombination, embryo development, negative regulation of DNA replication, protein phosphorylation, regulation of protein phosphorylation, response to DNA damage stimulus, response to UV Golgi apparatus, checkpoint clamp complex, nucleolus, nucleoplasm, nucleus protein binding Human HUS1B InterPro UniProtKB {GO:0030896=GO_REF:0000002, GO:0006281=GO_REF:0000002, GO:0005730=GO_REF:0000002, GO:0000077=GO_REF:0000002} Q8NHY5 Checkpoint protein HUS1B protein 20130413 {GO:0030896=IEA, GO:0006281=IEA, GO:0005730=IEA, GO:0000077=IEA} DNA damage checkpoint, DNA repair checkpoint clamp complex, nucleolus Human InterPro:IPR007150|InterPro:IPR016580 HUWE1 HPA UniProtKB {GO:0000209=PMID:15989957, GO:0005515=PMID:15989956, GO:0004842=PMID:19713937, GO:0006513=PMID:19713937, GO:0016574=PMID:15767685, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000024, GO:0030154=GO_REF:0000037, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0042787=GO_REF:0000033, GO:0006284=PMID:19713937} Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 protein 20080818 {GO:0000209=IDA, GO:0005515=IPI, GO:0004842=IDA, GO:0006513=IDA, GO:0016574=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=ISS, GO:0030154=IEA, GO:0005622=IEA, GO:0005737=IDA, GO:0042787=IBA, GO:0006284=IMP} base-excision repair, cell differentiation, histone ubiquitination, protein monoubiquitination, protein polyubiquitination, protein ubiquitination involved in ubiquitin-dependent protein catabolic process cytoplasm, intracellular, nucleolus, nucleus DNA binding, protein binding, ubiquitin-protein ligase activity Human HVCN1 HGNC UniProtKB {GO:0030171=PMID:16556803, GO:0016021=PMID:16554753, GO:0010043=PMID:16556803, GO:0009268=PMID:16556803, GO:0015992=PMID:16556803} Q96D96 Voltage-gated hydrogen channel 1 protein 20060428 {GO:0030171=ISS, GO:0016021=IDA, GO:0010043=ISS, GO:0009268=ISS, GO:0015992=ISS} proton transport, response to pH, response to zinc ion integral to membrane voltage-gated proton channel activity Human UniProtKB:Q3U2S8 HYAL1 HPA UniProtKB {GO:0030308=PMID:18725949, GO:0030307=PMID:20473947, GO:0051216=PMID:11944887, GO:0036117=PMID:16900089, GO:0044281=Reactome:REACT_111217, GO:0005615=PMID:21695196, GO:0071467=PMID:19478093, GO:0030207=Reactome:REACT_120888, GO:1900106=PMID:16900089, GO:0005737=GO_REF:0000052, GO:0001618=PMID:11296287, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121315, GO:0046677=PMID:11944887, GO:0043202=Reactome:REACT_121345, GO:0045927=PMID:21829529, GO:0050679=PMID:21829529, GO:0005975=Reactome:REACT_474, GO:0009615=PMID:11296287, GO:0045766=PMID:20473947, GO:0044344=PMID:19577615, GO:0045785=PMID:20473947, GO:0060272=GO_REF:0000019, GO:0030213=PMID:21829529, GO:0045750=PMID:21829529, GO:0030212=Reactome:REACT_121083, GO:0004415=PMID:11944887, GO:0050501=PMID:21829529, GO:0030214=Reactome:REACT_120996, GO:0010634=PMID:21829529, GO:0008134=PMID:18718911} Q12794 Hyaluronidase-1 protein 20080205 {GO:0030308=IDA, GO:0030307=IMP, GO:0051216=IEP, GO:0036117=IDA, GO:0044281=TAS, GO:0005615=IDA, GO:0071467=IDA, GO:0030207=TAS, GO:1900106=IDA, GO:0005737=IDA, GO:0001618=IDA, GO:0030204=TAS, GO:0030203=TAS, GO:0046677=IDA, GO:0043202=TAS, GO:0045927=IDA, GO:0050679=IDA, GO:0005975=TAS, GO:0009615=IDA, GO:0045766=IMP, GO:0044344=IDA, GO:0045785=IMP, GO:0060272=IEA, GO:0030213=IDA, GO:0045750=IDA, GO:0030212=TAS, GO:0004415=IDA, GO:0050501=IDA, GO:0030214=TAS, GO:0010634=IDA, GO:0008134=IDA} carbohydrate metabolic process, cartilage development, cellular response to fibroblast growth factor stimulus, cellular response to pH, chondroitin sulfate catabolic process, chondroitin sulfate metabolic process, embryonic skeletal joint morphogenesis, glycosaminoglycan metabolic process, hyaluronan biosynthetic process, hyaluronan catabolic process, hyaluronan metabolic process, negative regulation of cell growth, positive regulation of S phase of mitotic cell cycle, positive regulation of angiogenesis, positive regulation of cell adhesion, positive regulation of cell growth, positive regulation of epithelial cell migration, positive regulation of epithelial cell proliferation, positive regulation of growth, positive regulation of hyaluranon cable assembly, response to antibiotic, response to virus, small molecule metabolic process cytoplasm, extracellular space, hyaluranon cable, lysosomal lumen hyaluronan synthase activity, hyalurononglucosaminidase activity, transcription factor binding, viral receptor activity Human HYAL2 BHF-UCL UniProtKB {GO:0005515=PMID:12676986, GO:0030308=PMID:18725949, GO:0005886=Reactome:REACT_120971, GO:0005783=PMID:16191204, GO:0051216=PMID:11944887, GO:0048705=GO_REF:0000019, GO:0071560=PMID:19366691, GO:0030139=PMID:19366691, GO:0010259=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0046718=GO_REF:0000024, GO:0070295=GO_REF:0000024, GO:0031362=PMID:16191204, GO:0005829=PMID:19366691, GO:0051607=GO_REF:0000019, GO:0010764=PMID:19577615, GO:0002244=GO_REF:0000019, GO:0001618=PMID:16191204, GO:0045944=GO_REF:0000024, GO:0030203=Reactome:REACT_121315, GO:0046658=PMID:21740893, GO:0046677=PMID:11944887, GO:0030971=PMID:12676986, GO:0050431=GO_REF:0000024, GO:0019087=GO_REF:0000024, GO:0043065=GO_REF:0000024, GO:0009986=GO_REF:0000024, GO:0005975=Reactome:REACT_474, GO:0001822=GO_REF:0000024, GO:0019064=PMID:11296287, GO:0006027=PMID:9712871, GO:0009615=PMID:11296287, GO:0060586=GO_REF:0000019, GO:0044344=PMID:19577615, GO:0005902=PMID:19366691, GO:0000139=PMID:21740893, GO:0042117=PMID:19443707, GO:0030212=Reactome:REACT_121083, GO:0042307=GO_REF:0000024, GO:0045121=PMID:21740893, GO:0004415=Reactome:REACT_120971, GO:0030214=Reactome:REACT_120996, GO:0035810=GO_REF:0000024, GO:0019899=PMID:19366691} Q12891 Hyaluronidase-2 protein 20111215 {GO:0005515=IPI, GO:0030308=IDA, GO:0005886=TAS, GO:0005783=NAS, GO:0051216=IEP, GO:0048705=IEA, GO:0071560=IDA, GO:0030139=IDA, GO:0010259=IEA, GO:0044281=TAS, GO:0046718=ISS, GO:0070295=ISS, GO:0031362=IDA, GO:0005829=IDA, GO:0051607=IEA, GO:0010764=IDA, GO:0002244=IEA, GO:0001618=IDA, GO:0045944=ISS, GO:0030203=TAS, GO:0046658=IDA, GO:0046677=IEP, GO:0030971=IPI, GO:0050431=ISS, GO:0019087=ISS, GO:0043065=ISS, GO:0009986=ISS, GO:0005975=TAS, GO:0001822=ISS, GO:0019064=IDA, GO:0006027=IDA, GO:0009615=IDA, GO:0060586=IEA, GO:0044344=IDA, GO:0005902=IDA, GO:0000139=ISS, GO:0042117=IDA, GO:0030212=TAS, GO:0042307=ISS, GO:0045121=IDA, GO:0004415=TAS, GO:0030214=TAS, GO:0035810=ISS, GO:0019899=IPI} carbohydrate metabolic process, cartilage development, cellular response to fibroblast growth factor stimulus, cellular response to transforming growth factor beta stimulus, defense response to virus, glycosaminoglycan catabolic process, glycosaminoglycan metabolic process, hematopoietic progenitor cell differentiation, hyaluronan catabolic process, hyaluronan metabolic process, kidney development, monocyte activation, multicellular organismal aging, multicellular organismal iron ion homeostasis, negative regulation of cell growth, negative regulation of fibroblast migration, positive regulation of apoptotic process, positive regulation of protein import into nucleus, positive regulation of transcription from RNA polymerase II promoter, positive regulation of urine volume, renal water absorption, response to antibiotic, response to virus, skeletal system morphogenesis, small molecule metabolic process, transformation of host cell by virus, viral entry into host cell, viral entry into host cell via membrane fusion with the plasma membrane Golgi membrane, anchored to external side of plasma membrane, anchored to plasma membrane, cell surface, cytosol, endocytic vesicle, endoplasmic reticulum, membrane raft, microvillus, plasma membrane enzyme binding, hyalurononglucosaminidase activity, protein binding, receptor tyrosine kinase binding, transforming growth factor beta binding, viral receptor activity Human HYAL3 UniProtKB UniProtKB {GO:0051216=PMID:11944887, GO:0001618=PMID:11296287, GO:0005975=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0004415=PMID:11944887, GO:0009615=PMID:11296287, GO:0046677=PMID:11944887} O43820 Hyaluronidase-3 protein 20120217 {GO:0051216=IEP, GO:0001618=IDA, GO:0005975=IEA, GO:0005576=IEA, GO:0004415=IDA, GO:0009615=IDA, GO:0046677=IEP} carbohydrate metabolic process, cartilage development, response to antibiotic, response to virus extracellular region hyalurononglucosaminidase activity, viral receptor activity Human HYDIN InterPro UniProtKB {GO:0005198=GO_REF:0000002} H0YF91 Hydrocephalus-inducing protein homolog protein 20130413 {GO:0005198=IEA} structural molecule activity Human InterPro:IPR000535 HYI UniProtKB UniProtKB {GO:0008903=GO_REF:0000003} Q5T013 Putative hydroxypyruvate isomerase protein 20130413 {GO:0008903=IEA} hydroxypyruvate isomerase activity Human EC:5.3.1.22 HYLS1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005813=PMID:21399614, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q96M11 Hydrolethalus syndrome protein 1 protein 20111111 {GO:0005737=IDA, GO:0005813=IDA, GO:0005886=IDA, GO:0005730=IDA, GO:0005634=IDA} centrosome, cytoplasm, nucleolus, nucleus, plasma membrane Human HYOU1 Reactome UniProtKB {GO:0005783=PMID:9020069, GO:0006950=PMID:9020069, GO:0005788=Reactome:REACT_115877, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0005524=GO_REF:0000037, GO:0030968=Reactome:REACT_18356} Q9Y4L1 Hypoxia up-regulated protein 1 protein 20130301 {GO:0005783=TAS, GO:0006950=TAS, GO:0005788=TAS, GO:0006987=TAS, GO:0044267=TAS, GO:0005524=IEA, GO:0030968=TAS} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, response to stress endoplasmic reticulum, endoplasmic reticulum lumen ATP binding Human IAH1 UniProtKB UniProtKB {GO:0016042=GO_REF:0000037, GO:0006629=GO_REF:0000002, GO:0016787=GO_REF:0000002, GO:0016788=GO_REF:0000002} Q2TAA2 Isoamyl acetate-hydrolyzing esterase 1 homolog protein 20130413 {GO:0016042=IEA, GO:0006629=IEA, GO:0016787=IEA, GO:0016788=IEA} lipid catabolic process, lipid metabolic process hydrolase activity, hydrolase activity, acting on ester bonds Human UniProtKB-KW:KW-0442 IAPP Reactome UniProtKB {GO:0007165=PMID:10342886, GO:0005179=GO_REF:0000037, GO:0031018=Reactome:REACT_13819, GO:0007267=PMID:2608057, GO:0005102=PMID:2608057, GO:0043025=GO_REF:0000019, GO:0006915=PMID:8152488, GO:0005576=Reactome:REACT_75905, GO:0045596=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0045779=GO_REF:0000019, GO:0019233=GO_REF:0000019} P10997 Islet amyloid polypeptide protein 20130301 {GO:0007165=TAS, GO:0005179=IEA, GO:0031018=TAS, GO:0007267=TAS, GO:0005102=TAS, GO:0043025=IEA, GO:0006915=TAS, GO:0005576=TAS, GO:0045596=IEA, GO:0005615=IEA, GO:0045779=IEA, GO:0019233=IEA} apoptotic process, cell-cell signaling, endocrine pancreas development, negative regulation of bone resorption, negative regulation of cell differentiation, sensory perception of pain, signal transduction extracellular region, extracellular space, neuronal cell body hormone activity, receptor binding Human IARS InterPro UniProtKB {GO:0005515=PMID:9556618, GO:0010467=Reactome:REACT_71, GO:0005737=GO_REF:0000002, GO:0002161=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006428=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0004822=GO_REF:0000002, GO:0004812=GO_REF:0000002, GO:0006418=GO_REF:0000002, GO:0005829=Reactome:REACT_15516} Q5TCD1 Isoleucine--tRNA ligase, cytoplasmic protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0005737=IEA, GO:0002161=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006428=IEA, GO:0005524=IEA, GO:0004822=IEA, GO:0004812=IEA, GO:0006418=IEA, GO:0005829=TAS} gene expression, isoleucyl-tRNA aminoacylation, tRNA aminoacylation for protein translation cytoplasm, cytosol, nucleolus, nucleus ATP binding, aminoacyl-tRNA editing activity, aminoacyl-tRNA ligase activity, isoleucine-tRNA ligase activity, protein binding Human InterPro:IPR002301 IARS2 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0010467=Reactome:REACT_71, GO:0005737=GO_REF:0000052, GO:0002161=GO_REF:0000002, GO:0005759=Reactome:REACT_15423, GO:0006428=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0004822=GO_REF:0000003, GO:0006418=Reactome:REACT_15482} Q9NSE4 Isoleucine--tRNA ligase, mitochondrial protein 20101115 {GO:0005739=IDA, GO:0010467=TAS, GO:0005737=IDA, GO:0002161=IEA, GO:0005759=TAS, GO:0006428=IEA, GO:0005524=IEA, GO:0004822=IEA, GO:0006418=TAS} gene expression, isoleucyl-tRNA aminoacylation, tRNA aminoacylation for protein translation cytoplasm, mitochondrial matrix, mitochondrion ATP binding, aminoacyl-tRNA editing activity, isoleucine-tRNA ligase activity Human IBA57 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0006546=GO_REF:0000002, GO:0004047=GO_REF:0000002, GO:0006783=GO_REF:0000037} Q5T440 Putative transferase CAF17, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0006546=IEA, GO:0004047=IEA, GO:0006783=IEA} glycine catabolic process, heme biosynthetic process mitochondrion aminomethyltransferase activity Human UniProtKB-SubCell:SL-0173 IBSP Reactome UniProtKB {GO:0071363=GO_REF:0000019, GO:0001503=GO_REF:0000002, GO:0030198=GO_REF:0000019, GO:0005576=Reactome:REACT_13402, GO:0007155=GO_REF:0000037, GO:0031214=GO_REF:0000037} P21815 Bone sialoprotein 2 protein 20100804 {GO:0071363=IEA, GO:0001503=IEA, GO:0030198=IEA, GO:0005576=TAS, GO:0007155=IEA, GO:0031214=IEA} biomineral tissue development, cell adhesion, cellular response to growth factor stimulus, extracellular matrix organization, ossification extracellular region Human IBTK HPA UniProtKB {GO:0005737=PMID:11577348, GO:0051209=PMID:11577348, GO:0019901=PMID:11577348, GO:0016020=GO_REF:0000039, GO:0061099=PMID:11577348, GO:0030292=PMID:11577348, GO:0005730=GO_REF:0000052, GO:0001933=PMID:11577348, GO:0005634=GO_REF:0000052} Q9P2D0 Inhibitor of Bruton tyrosine kinase protein 20100326 {GO:0005737=IDA, GO:0051209=IDA, GO:0019901=IDA, GO:0016020=IEA, GO:0061099=IDA, GO:0030292=IDA, GO:0005730=IDA, GO:0001933=IDA, GO:0005634=IDA} negative regulation of protein phosphorylation, negative regulation of protein tyrosine kinase activity, release of sequestered calcium ion into cytosol cytoplasm, membrane, nucleolus, nucleus protein kinase binding, protein tyrosine kinase inhibitor activity NOT Human ICA1 HPA UniProtKB {GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0030054=GO_REF:0000037, GO:0000139=PMID:12682071, GO:0019904=GO_REF:0000002, GO:0006836=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0030672=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0030667=PMID:12682071, GO:0030658=GO_REF:0000039, GO:0005829=GO_REF:0000024} Q96HG3 Islet cell autoantigen 1, 69kDa protein 20090616 {GO:0003674=ND, GO:0005737=IDA, GO:0030054=IEA, GO:0000139=IDA, GO:0019904=IEA, GO:0006836=IEA, GO:0005730=IDA, GO:0030672=ISS, GO:0005634=IDA, GO:0030667=IDA, GO:0030658=IEA, GO:0005829=ISS} neurotransmitter transport Golgi membrane, cell junction, cytoplasm, cytosol, nucleolus, nucleus, secretory granule membrane, synaptic vesicle membrane, transport vesicle membrane molecular_function, protein domain specific binding Human ICAM1 BHF-UCL UniProtKB {GO:0005515=PMID:12716892, GO:0014070=GO_REF:0000019, GO:0043498=GO_REF:0000019, GO:0008360=GO_REF:0000019, GO:0019221=Reactome:REACT_25229, GO:0050900=PMID:12082081, GO:0030155=GO_REF:0000019, GO:0005615=PMID:9290466, GO:0016337=GO_REF:0000002, GO:0031669=GO_REF:0000019, GO:0071356=GO_REF:0000019, GO:0051926=GO_REF:0000019, GO:0060333=Reactome:REACT_25078, GO:0007569=GO_REF:0000019, GO:0071312=GO_REF:0000019, GO:0005178=PMID:1448173, GO:0005887=PMID:2538243, GO:0071347=GO_REF:0000019, GO:0050776=Reactome:REACT_11152, GO:0046688=GO_REF:0000019, GO:0002457=GO_REF:0000019, GO:0009897=GO_REF:0000019, GO:0004888=PMID:2538243, GO:0033627=GO_REF:0000019, GO:0005886=Reactome:REACT_25082, GO:0045471=GO_REF:0000019, GO:0051856=PMID:2538243, GO:0045429=GO_REF:0000019, GO:0001541=GO_REF:0000019, GO:0051092=GO_REF:0000019, GO:0045907=GO_REF:0000019, GO:0010212=GO_REF:0000019, GO:0007159=PMID:2477710, GO:0022614=PMID:12082081, GO:0004872=PMID:2538243, GO:0071333=GO_REF:0000019, GO:0007155=PMID:16809613, GO:0043200=GO_REF:0000019, GO:0007157=PMID:2477710, GO:0001772=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0071456=GO_REF:0000019, GO:0002693=PMID:12902516, GO:0034698=GO_REF:0000019, GO:0001975=GO_REF:0000019, GO:0071222=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0002291=PMID:2477710, GO:0001910=PMID:16038038, GO:0010477=GO_REF:0000019, GO:0046813=PMID:2538243} P05362 Intercellular adhesion molecule 1 protein 20081128 {GO:0005515=IPI, GO:0014070=IEA, GO:0043498=IEA, GO:0008360=IEA, GO:0019221=TAS, GO:0050900=IEP, GO:0030155=IEA, GO:0005615=IDA, GO:0016337=IEA, GO:0031669=IEA, GO:0071356=IEA, GO:0051926=IEA, GO:0060333=TAS, GO:0007569=IEA, GO:0071312=IEA, GO:0005178=IPI, GO:0005887=TAS, GO:0071347=IEA, GO:0050776=TAS, GO:0046688=IEA, GO:0002457=IEA, GO:0009897=IEA, GO:0004888=TAS, GO:0033627=IEA, GO:0005886=TAS, GO:0045471=IEA, GO:0051856=IDA, GO:0045429=IEA, GO:0001541=IEA, GO:0051092=IEA, GO:0045907=IEA, GO:0010212=IEA, GO:0007159=IMP, GO:0022614=IEP, GO:0004872=TAS, GO:0071333=IEA, GO:0007155=IDA, GO:0043200=IEA, GO:0007157=TAS, GO:0001772=IEA, GO:0042493=IEA, GO:0071456=IEA, GO:0002693=IMP, GO:0034698=IEA, GO:0001975=IEA, GO:0071222=IEA, GO:0016020=IEA, GO:0002291=IMP, GO:0001910=TAS, GO:0010477=IEA, GO:0046813=IDA} T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell, T cell antigen processing and presentation, adhesion to symbiont, cell adhesion, cell adhesion mediated by integrin, cell aging, cell-cell adhesion, cellular response to alkaloid, cellular response to glucose stimulus, cellular response to hypoxia, cellular response to interleukin-1, cellular response to lipopolysaccharide, cellular response to nutrient levels, cellular response to tumor necrosis factor, cytokine-mediated signaling pathway, heterophilic cell-cell adhesion, interferon-gamma-mediated signaling pathway, leukocyte cell-cell adhesion, leukocyte migration, membrane to membrane docking, negative regulation of calcium ion transport, ovarian follicle development, positive regulation of NF-kappaB transcription factor activity, positive regulation of cellular extravasation, positive regulation of nitric oxide biosynthetic process, positive regulation of vasoconstriction, regulation of cell adhesion, regulation of cell shape, regulation of immune response, regulation of leukocyte mediated cytotoxicity, response to amino acid stimulus, response to amphetamine, response to copper ion, response to drug, response to ethanol, response to gonadotropin stimulus, response to ionizing radiation, response to organic cyclic compound, response to sulfur dioxide, virion attachment, binding of host cell surface receptor external side of plasma membrane, extracellular space, immunological synapse, integral to plasma membrane, membrane, plasma membrane cell surface binding, integrin binding, protein binding, receptor activity, transmembrane signaling receptor activity Human ICAM2 BHF-UCL UniProtKB {GO:0016337=GO_REF:0000002, GO:0005178=PMID:1448173, GO:0005886=Reactome:REACT_11173, GO:0016020=GO_REF:0000002, GO:0005887=GO_REF:0000019, GO:0050776=Reactome:REACT_11152, GO:0001931=GO_REF:0000019} P13598 Intercellular adhesion molecule 2 protein 20081128 {GO:0016337=IEA, GO:0005178=IPI, GO:0005886=TAS, GO:0016020=IEA, GO:0005887=IEA, GO:0050776=TAS, GO:0001931=IEA} cell-cell adhesion, regulation of immune response integral to plasma membrane, membrane, plasma membrane, uropod integrin binding Human UniProtKB:P20701 ICAM3 BHF-UCL UniProtKB {GO:0005515=PMID:12082081, GO:0016337=GO_REF:0000002, GO:0005178=PMID:1448173, GO:0005886=Reactome:REACT_11173, GO:0016020=GO_REF:0000002, GO:0005887=PMID:8459213, GO:0050776=Reactome:REACT_11152, GO:0005102=PMID:8459213} P32942 Intercellular adhesion molecule 3 protein 20081128 {GO:0005515=IPI, GO:0016337=IEA, GO:0005178=IPI, GO:0005886=TAS, GO:0016020=IEA, GO:0005887=TAS, GO:0050776=TAS, GO:0005102=TAS} cell-cell adhesion, regulation of immune response integral to plasma membrane, membrane, plasma membrane integrin binding, protein binding, receptor binding Human UniProtKB:P20701 ICAM4 Reactome UniProtKB {GO:0016337=GO_REF:0000002, GO:0005178=PMID:8566017, GO:0005886=Reactome:REACT_11173, GO:0050776=Reactome:REACT_11152, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q14773 Intercellular adhesion molecule 4 protein 20130228 {GO:0016337=IEA, GO:0005178=TAS, GO:0005886=TAS, GO:0050776=TAS, GO:0005576=IEA, GO:0016021=IEA} cell-cell adhesion, regulation of immune response extracellular region, integral to membrane, plasma membrane integrin binding Human ICAM5 IntAct UniProtKB {GO:0005515=PMID:16820411, GO:0006909=GO_REF:0000019, GO:0016337=GO_REF:0000002, GO:0005886=PMID:8995416, GO:0016020=GO_REF:0000002, GO:0005887=PMID:8995416} Q9UMF0 Intercellular adhesion molecule 5 protein 20130415 {GO:0005515=IPI, GO:0006909=IEA, GO:0016337=IEA, GO:0005886=TAS, GO:0016020=IEA, GO:0005887=TAS} cell-cell adhesion, phagocytosis integral to plasma membrane, membrane, plasma membrane protein binding Human UniProtKB:P05094 ICK HPA UniProtKB {GO:0005515=PMID:22939624, GO:0007165=PMID:10699974, GO:0000287=PMID:10699974, GO:0004674=PMID:10699974, GO:0006468=PMID:10699974, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0005524=PMID:10699974, GO:0007243=PMID:10699974, GO:0043231=GO_REF:0000052, GO:0005829=GO_REF:0000039, GO:0004693=GO_REF:0000003} Q9UPZ9 Serine/threonine-protein kinase ICK protein 20080818 {GO:0005515=IPI, GO:0007165=TAS, GO:0000287=IDA, GO:0004674=IDA, GO:0006468=IDA, GO:0005634=IEA, GO:0007275=IEA, GO:0005524=IDA, GO:0007243=IDA, GO:0043231=IDA, GO:0005829=IEA, GO:0004693=IEA} intracellular protein kinase cascade, multicellular organismal development, protein phosphorylation, signal transduction cytosol, intracellular membrane-bounded organelle, nucleus ATP binding, cyclin-dependent protein serine/threonine kinase activity, magnesium ion binding, protein binding, protein serine/threonine kinase activity Human ICMT MGI UniProtKB {GO:0008284=GO_REF:0000019, GO:0005783=PMID:9614111, GO:0046578=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0001889=GO_REF:0000019, GO:0004671=GO_REF:0000003, GO:0008140=GO_REF:0000019, GO:0035264=GO_REF:0000019, GO:0016020=PMID:10441503, GO:0006481=PMID:10441503, GO:0006612=PMID:9614111, GO:0005789=GO_REF:0000039, GO:0003880=PMID:9614111, GO:0016021=GO_REF:0000037, GO:0006464=PMID:9614111} O60725 Protein-S-isoprenylcysteine O-methyltransferase protein 20080501 {GO:0008284=IEA, GO:0005783=IDA, GO:0046578=IEA, GO:0001701=IEA, GO:0001889=IEA, GO:0004671=IEA, GO:0008140=IEA, GO:0035264=IEA, GO:0016020=TAS, GO:0006481=TAS, GO:0006612=TAS, GO:0005789=IEA, GO:0003880=TAS, GO:0016021=IEA, GO:0006464=TAS} C-terminal protein methylation, cellular protein modification process, in utero embryonic development, liver development, multicellular organism growth, positive regulation of cell proliferation, protein targeting to membrane, regulation of Ras protein signal transduction endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, membrane cAMP response element binding protein binding, protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity, protein C-terminal carboxyl O-methyltransferase activity Human ICOS Reactome UniProtKB {GO:0006955=PMID:9930702, GO:0016337=GO_REF:0000019, GO:0002517=GO_REF:0000019, GO:0005886=Reactome:REACT_19418, GO:0005887=GO_REF:0000019, GO:0031295=Reactome:REACT_19344, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000029, GO:0009897=GO_REF:0000019} Q9Y6W8 Inducible T-cell costimulator protein 20070516 {GO:0006955=NAS, GO:0016337=IEA, GO:0002517=IEA, GO:0005886=TAS, GO:0005887=IEA, GO:0031295=TAS, GO:0005576=IEA, GO:0016021=NAS, GO:0009897=IEA} T cell costimulation, T cell tolerance induction, cell-cell adhesion, immune response external side of plasma membrane, extracellular region, integral to membrane, integral to plasma membrane, plasma membrane Human ICOSLG Reactome UniProtKB {GO:0005886=Reactome:REACT_19418, GO:0045404=GO_REF:0000019, GO:0031295=Reactome:REACT_19344, GO:0005102=PMID:11429535, GO:0006952=PMID:11983910, GO:0006972=PMID:12145647, GO:0042113=GO_REF:0000037, GO:0007165=PMID:12145647, GO:0042104=PMID:11429535, GO:0042110=PMID:11983910, GO:0016020=GO_REF:0000038, GO:0005887=GO_REF:0000019, GO:0016021=PMID:12145647, GO:0009897=GO_REF:0000019} O75144 ICOS ligand protein 20090529 {GO:0005886=TAS, GO:0045404=IEA, GO:0031295=TAS, GO:0005102=TAS, GO:0006952=NAS, GO:0006972=NAS, GO:0042113=IEA, GO:0007165=NAS, GO:0042104=TAS, GO:0042110=NAS, GO:0016020=IEA, GO:0005887=IEA, GO:0016021=NAS, GO:0009897=IEA} B cell activation, T cell activation, T cell costimulation, defense response, hyperosmotic response, positive regulation of activated T cell proliferation, positive regulation of interleukin-4 biosynthetic process, signal transduction external side of plasma membrane, integral to membrane, integral to plasma membrane, membrane, plasma membrane receptor binding Human ICT1 UniProtKB UniProtKB {GO:0005739=PMID:20186120, GO:0070126=PMID:20186120, GO:0004045=PMID:20186120, GO:0016150=PMID:20186120, GO:0003747=GO_REF:0000002, GO:0005762=PMID:20186120} Q14197 Peptidyl-tRNA hydrolase ICT1, mitochondrial protein 20100305 {GO:0005739=IDA, GO:0070126=IDA, GO:0004045=IDA, GO:0016150=IDA, GO:0003747=IEA, GO:0005762=IDA} mitochondrial translational termination mitochondrial large ribosomal subunit, mitochondrion aminoacyl-tRNA hydrolase activity, translation release factor activity, translation release factor activity, codon nonspecific Human ID1 BHF-UCL UniProtKB {GO:0005515=PMID:15694377, GO:0060426=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0060425=GO_REF:0000019, GO:0048514=PMID:14522471, GO:0005634=GO_REF:0000039, GO:0043433=PMID:15138269, GO:0031648=GO_REF:0000019, GO:0007507=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0043408=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0007179=PMID:14522471, GO:0046677=GO_REF:0000019, GO:0006915=GO_REF:0000019, GO:0045765=GO_REF:0000019, GO:0030509=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0001525=PMID:14522471, GO:0006351=GO_REF:0000019, GO:0043392=GO_REF:0000019, GO:0043534=PMID:14522471, GO:0045668=GO_REF:0000019, GO:0001886=GO_REF:0000019, GO:0032963=GO_REF:0000019, GO:0045892=PMID:15138269, GO:0010621=PMID:14522471} P41134 DNA-binding protein inhibitor ID-1 protein 20090114 {GO:0005515=IPI, GO:0060426=IEA, GO:0003700=IEA, GO:0060425=IEA, GO:0048514=TAS, GO:0005634=IEA, GO:0043433=IDA, GO:0031648=IEA, GO:0007507=IEA, GO:0005737=IEA, GO:0043408=IEA, GO:0046983=IEA, GO:0007179=TAS, GO:0046677=IEA, GO:0006915=IEA, GO:0045765=IEA, GO:0030509=IEA, GO:0000122=IEA, GO:0001525=TAS, GO:0006351=IEA, GO:0043392=IEA, GO:0043534=TAS, GO:0045668=IEA, GO:0001886=IEA, GO:0032963=IEA, GO:0045892=IDA, GO:0010621=TAS} BMP signaling pathway, angiogenesis, apoptotic process, blood vessel endothelial cell migration, blood vessel morphogenesis, collagen metabolic process, endothelial cell morphogenesis, heart development, lung morphogenesis, lung vasculature development, negative regulation of DNA binding, negative regulation of osteoblast differentiation, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription by transcription factor localization, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, protein destabilization, regulation of MAPK cascade, regulation of angiogenesis, response to antibiotic, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway cytoplasm, nucleus protein binding, protein dimerization activity, sequence-specific DNA binding transcription factor activity Human ID2 HPA UniProtKB {GO:0001656=GO_REF:0000019, GO:0005515=PMID:10915743, GO:0043353=GO_REF:0000019, GO:2000045=PMID:16311606, GO:0071158=GO_REF:0000024, GO:0048541=GO_REF:0000019, GO:0009649=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0000785=GO_REF:0000019, GO:0071285=GO_REF:0000019, GO:2000178=GO_REF:0000024, GO:0007275=PMID:1741406, GO:0000122=GO_REF:0000019, GO:0045651=GO_REF:0000019, GO:0045787=GO_REF:0000019, GO:0044325=PMID:16311606, GO:0019216=GO_REF:0000019, GO:0043392=GO_REF:0000019, GO:0071931=PMID:16311606, GO:0043234=GO_REF:0000024, GO:0033598=GO_REF:0000024, GO:0045648=GO_REF:0000019, GO:0045600=GO_REF:0000019, GO:0045893=GO_REF:0000024, GO:0045892=PMID:14627819, GO:0090398=GO_REF:0000024, GO:0045578=GO_REF:0000019, GO:0003166=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0045777=GO_REF:0000024, GO:0043433=PMID:14627819, GO:0005829=PMID:16311606, GO:0005737=GO_REF:0000052, GO:0021772=GO_REF:0000019, GO:0001779=GO_REF:0000019, GO:0048469=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0048663=GO_REF:0000024, GO:0048661=GO_REF:0000024, GO:0010628=GO_REF:0000024, GO:0048711=GO_REF:0000019, GO:0045668=GO_REF:0000019, GO:0045665=GO_REF:0000024, GO:0048557=GO_REF:0000024, GO:0014003=GO_REF:0000019, GO:0048715=GO_REF:0000019, GO:0010629=GO_REF:0000024, GO:0060612=GO_REF:0000019, GO:0061030=GO_REF:0000024, GO:0060749=GO_REF:0000024, GO:0061031=GO_REF:0000024} Q02363 DNA-binding protein inhibitor ID-2 protein 20101115 {GO:0001656=IEA, GO:0005515=IPI, GO:0043353=IEA, GO:2000045=IMP, GO:0071158=ISS, GO:0048541=IEA, GO:0009649=IEA, GO:0046983=IEA, GO:0000785=IEA, GO:0071285=IEA, GO:2000178=ISS, GO:0007275=TAS, GO:0000122=IEA, GO:0045651=IEA, GO:0045787=IEA, GO:0044325=IPI, GO:0019216=IEA, GO:0043392=IEA, GO:0071931=IC, GO:0043234=ISS, GO:0033598=ISS, GO:0045648=IEA, GO:0045600=IEA, GO:0045893=ISS, GO:0045892=IDA, GO:0090398=ISS, GO:0045578=IEA, GO:0003166=IEA, GO:0005634=IDA, GO:0045777=ISS, GO:0043433=IDA, GO:0005829=IDA, GO:0005737=IDA, GO:0021772=IEA, GO:0001779=IEA, GO:0048469=IEA, GO:0005730=IDA, GO:0048663=ISS, GO:0048661=ISS, GO:0010628=ISS, GO:0048711=IEA, GO:0045668=IEA, GO:0045665=ISS, GO:0048557=ISS, GO:0014003=IEA, GO:0048715=IEA, GO:0010629=ISS, GO:0060612=IEA, GO:0061030=ISS, GO:0060749=ISS, GO:0061031=ISS} Peyer's patch development, adipose tissue development, bundle of His development, cell maturation, cellular response to lithium ion, cellular senescence, embryonic digestive tract morphogenesis, endodermal digestive tract morphogenesis, entrainment of circadian clock, enucleate erythrocyte differentiation, epithelial cell differentiation involved in mammary gland alveolus development, mammary gland alveolus development, mammary gland epithelial cell proliferation, metanephros development, multicellular organismal development, natural killer cell differentiation, negative regulation of B cell differentiation, negative regulation of DNA binding, negative regulation of gene expression, negative regulation of neural precursor cell proliferation, negative regulation of neuron differentiation, negative regulation of oligodendrocyte differentiation, negative regulation of osteoblast differentiation, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, neuron fate commitment, olfactory bulb development, oligodendrocyte development, positive regulation of astrocyte differentiation, positive regulation of blood pressure, positive regulation of cell cycle, positive regulation of cell cycle arrest, positive regulation of erythrocyte differentiation, positive regulation of fat cell differentiation, positive regulation of gene expression, positive regulation of macrophage differentiation, positive regulation of smooth muscle cell proliferation, positive regulation of transcription involved in G1/S phase of mitotic cell cycle, positive regulation of transcription, DNA-dependent, regulation of G1/S transition of mitotic cell cycle, regulation of lipid metabolic process chromatin, cytoplasm, cytosol, nucleolus, nucleus, protein complex ion channel binding, protein binding, protein dimerization activity Human ID3 GDB UniProtKB {GO:0001656=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0043433=PMID:14627819, GO:0007507=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0030182=GO_REF:0000019, GO:0030855=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0042476=GO_REF:0000019, GO:0051726=GO_REF:0000019, GO:0006275=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0003714=PMID:8437843, GO:0019904=GO_REF:0000019, GO:0009611=GO_REF:0000019, GO:0007275=PMID:1628620, GO:0000122=GO_REF:0000019, GO:0007417=GO_REF:0000019, GO:0006351=GO_REF:0000019, GO:0007517=GO_REF:0000037, GO:0045668=GO_REF:0000019, GO:0030903=GO_REF:0000019, GO:0045892=PMID:14627819, GO:0008134=GO_REF:0000019} Q02535 DNA-binding protein inhibitor ID-3 protein 20060216 {GO:0001656=IEA, GO:0003700=IEA, GO:0005634=IEA, GO:0043433=IDA, GO:0007507=IEA, GO:0005737=IEA, GO:0030182=IEA, GO:0030855=IEA, GO:0046983=IEA, GO:0042476=IEA, GO:0051726=IEA, GO:0006275=IEA, GO:0043065=IEA, GO:0003714=TAS, GO:0019904=IEA, GO:0009611=IEA, GO:0007275=TAS, GO:0000122=IEA, GO:0007417=IEA, GO:0006351=IEA, GO:0007517=IEA, GO:0045668=IEA, GO:0030903=IEA, GO:0045892=IDA, GO:0008134=IEA} central nervous system development, epithelial cell differentiation, heart development, metanephros development, multicellular organismal development, muscle organ development, negative regulation of osteoblast differentiation, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, neuron differentiation, notochord development, odontogenesis, positive regulation of apoptotic process, regulation of DNA replication, regulation of cell cycle, response to wounding, transcription, DNA-dependent cytoplasm, nucleus protein dimerization activity, protein domain specific binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity, transcription factor binding Human ID4 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0008284=GO_REF:0000019, GO:0006357=PMID:7665172, GO:0022010=GO_REF:0000019, GO:0045599=GO_REF:0000019, GO:0003714=PMID:7665172, GO:0005634=PMID:11136250, GO:0000122=GO_REF:0000019, GO:0007405=GO_REF:0000019, GO:0048712=GO_REF:0000019, GO:0045669=GO_REF:0000019, GO:0021766=GO_REF:0000019, GO:0000082=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0045665=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0048715=GO_REF:0000019, GO:0001085=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0045444=GO_REF:0000019, GO:0034613=GO_REF:0000019, GO:0045892=PMID:11136250, GO:0021895=GO_REF:0000019} P47928 DNA-binding protein inhibitor ID-4 protein 20130415 {GO:0005515=IPI, GO:0008284=IEA, GO:0006357=TAS, GO:0022010=IEA, GO:0045599=IEA, GO:0003714=TAS, GO:0005634=IC, GO:0000122=IEA, GO:0007405=IEA, GO:0048712=IEA, GO:0045669=IEA, GO:0021766=IEA, GO:0000082=IEA, GO:0005737=IEA, GO:0045665=IEA, GO:0045944=IEA, GO:0048715=IEA, GO:0001085=IEA, GO:0046983=IEA, GO:0045444=IEA, GO:0034613=IEA, GO:0045892=IDA, GO:0021895=IEA} G1/S transition of mitotic cell cycle, cellular protein localization, central nervous system myelination, cerebral cortex neuron differentiation, fat cell differentiation, hippocampus development, negative regulation of astrocyte differentiation, negative regulation of fat cell differentiation, negative regulation of neuron differentiation, negative regulation of oligodendrocyte differentiation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, neuroblast proliferation, positive regulation of cell proliferation, positive regulation of osteoblast differentiation, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter cytoplasm, nucleus RNA polymerase II transcription factor binding, protein binding, protein dimerization activity, transcription corepressor activity Human UniProtKB:P16333 IDE InterPro UniProtKB {GO:0008286=PMID:3059494, GO:0005515=PMID:17715127, GO:0031597=GO_REF:0000019, GO:0043130=PMID:21185309, GO:0010992=PMID:21185309, GO:0005886=GO_REF:0000039, GO:0005782=GO_REF:0000019, GO:0005634=PMID:15285718, GO:0010815=PMID:21185309, GO:0008340=PMID:18448515, GO:0051291=GO_REF:0000019, GO:0046872=GO_REF:0000002, GO:0042803=PMID:17613531, GO:0005829=PMID:15285718, GO:0005739=PMID:15285718, GO:0005737=PMID:9231799, GO:0001540=GO_REF:0000019, GO:0001948=PMID:17055432, GO:0051289=GO_REF:0000019, GO:0006508=GO_REF:0000002, GO:0051260=PMID:17051221, GO:1901142=PMID:18448515, GO:1901143=PMID:9231799, GO:0016887=GO_REF:0000019, GO:0043559=PMID:20082125, GO:0031626=GO_REF:0000019, GO:0005777=PMID:9231799, GO:0042277=PMID:20082125, GO:0009986=PMID:17055432, GO:0005102=PMID:20178365, GO:0005524=PMID:17613531, GO:0050435=PMID:17613531, GO:0045861=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0042447=GO_REF:0000019, GO:0008270=PMID:17613531, GO:0004222=GO_REF:0000002} Q5T5N3 Insulin-degrading enzyme protein 20130413 {GO:0008286=NAS, GO:0005515=IPI, GO:0031597=IEA, GO:0043130=IPI, GO:0010992=IDA, GO:0005886=IEA, GO:0005782=IEA, GO:0005634=IDA, GO:0010815=IDA, GO:0008340=IDA, GO:0051291=IEA, GO:0046872=IEA, GO:0042803=IPI, GO:0005829=IDA, GO:0005739=IDA, GO:0005737=IDA, GO:0001540=IEA, GO:0001948=IPI, GO:0051289=IEA, GO:0006508=IEA, GO:0051260=IDA, GO:1901142=IDA, GO:1901143=IDA, GO:0016887=IEA, GO:0043559=IPI, GO:0031626=IEA, GO:0005777=IDA, GO:0042277=IPI, GO:0009986=IDA, GO:0005102=IPI, GO:0005524=IDA, GO:0050435=IDA, GO:0045861=IEA, GO:0019048=IEA, GO:0042447=IEA, GO:0008270=IDA, GO:0004222=IEA} beta-amyloid metabolic process, bradykinin catabolic process, determination of adult lifespan, hormone catabolic process, insulin catabolic process, insulin metabolic process, insulin receptor signaling pathway, negative regulation of proteolysis, protein heterooligomerization, protein homooligomerization, protein homotetramerization, proteolysis, ubiquitin homeostasis, virus-host interaction cell surface, cytoplasm, cytosol, cytosolic proteasome complex, mitochondrion, nucleus, peroxisomal matrix, peroxisome, plasma membrane ATP binding, ATPase activity, beta-amyloid binding, beta-endorphin binding, glycoprotein binding, insulin binding, metal ion binding, metalloendopeptidase activity, peptide binding, protein binding, protein homodimerization activity, receptor binding, ubiquitin binding, zinc ion binding Human InterPro:IPR011237|InterPro:IPR011249 IDH1 LIFEdb UniProtKB {GO:0050661=GO_REF:0000019, GO:0000287=PMID:19935646, GO:0006099=GO_REF:0000037, GO:0005782=Reactome:REACT_16932, GO:0005102=PMID:20178365, GO:0006749=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0048545=GO_REF:0000019, GO:0006097=GO_REF:0000037, GO:0042803=PMID:19935646, GO:0004450=Reactome:REACT_17007, GO:0005829=Reactome:REACT_25008, GO:0006102=PMID:20171178, GO:0005739=GO_REF:0000019, GO:0008585=GO_REF:0000019, GO:0005737=GO_REF:0000054, GO:0051287=GO_REF:0000002, GO:0006740=Reactome:REACT_16904, GO:0006103=Reactome:REACT_160183, GO:0006979=GO_REF:0000019, GO:0044255=Reactome:REACT_16957, GO:0005777=PMID:10521434} O75874 "Isocitrate dehydrogenase ""NADP"" cytoplasmic" protein 20100607 {GO:0050661=IEA, GO:0000287=IDA, GO:0006099=IEA, GO:0005782=TAS, GO:0005102=IPI, GO:0006749=IEA, GO:0044281=TAS, GO:0048545=IEA, GO:0006097=IEA, GO:0042803=IPI, GO:0004450=EXP, GO:0005829=TAS, GO:0006102=IDA, GO:0005739=IEA, GO:0008585=IEA, GO:0005737=IDA, GO:0051287=IEA, GO:0006740=TAS, GO:0006103=TAS, GO:0006979=IEA, GO:0044255=TAS, GO:0005777=IDA} 2-oxoglutarate metabolic process, NADPH regeneration, cellular lipid metabolic process, female gonad development, glutathione metabolic process, glyoxylate cycle, isocitrate metabolic process, response to oxidative stress, response to steroid hormone stimulus, small molecule metabolic process, tricarboxylic acid cycle cytoplasm, cytosol, mitochondrion, peroxisomal matrix, peroxisome NAD binding, NADP binding, isocitrate dehydrogenase (NADP+) activity, magnesium ion binding, protein homodimerization activity, receptor binding Human IDH2 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0006102=GO_REF:0000024, GO:0006099=Reactome:REACT_1785, GO:0051287=GO_REF:0000002, GO:0000287=GO_REF:0000024, GO:0005975=PMID:8954790, GO:0005759=Reactome:REACT_21355, GO:0006103=GO_REF:0000024, GO:0005743=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0006097=GO_REF:0000037, GO:0004450=Reactome:REACT_21355} P48735 "Isocitrate dehydrogenase ""NADP"", mitochondrial" protein 20090616 {GO:0005739=IDA, GO:0006102=ISS, GO:0006099=TAS, GO:0051287=IEA, GO:0000287=ISS, GO:0005975=NAS, GO:0005759=TAS, GO:0006103=ISS, GO:0005743=IEA, GO:0044281=TAS, GO:0006097=IEA, GO:0004450=EXP} 2-oxoglutarate metabolic process, carbohydrate metabolic process, glyoxylate cycle, isocitrate metabolic process, small molecule metabolic process, tricarboxylic acid cycle mitochondrial inner membrane, mitochondrial matrix, mitochondrion NAD binding, isocitrate dehydrogenase (NADP+) activity, magnesium ion binding Human IDH3A HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0006099=Reactome:REACT_1785, GO:0051287=GO_REF:0000002, GO:0000287=GO_REF:0000002, GO:0004449=GO_REF:0000003, GO:0005975=PMID:8833160, GO:0005759=Reactome:REACT_1068, GO:0044281=Reactome:REACT_111217, GO:0016616=GO_REF:0000002} P50213 "Isocitrate dehydrogenase ""NAD"" subunit alpha, mitochondrial" protein 20111111 {GO:0005739=IDA, GO:0006099=TAS, GO:0051287=IEA, GO:0000287=IEA, GO:0004449=IEA, GO:0005975=NAS, GO:0005759=TAS, GO:0044281=TAS, GO:0016616=IEA} carbohydrate metabolic process, small molecule metabolic process, tricarboxylic acid cycle mitochondrial matrix, mitochondrion NAD binding, isocitrate dehydrogenase (NAD+) activity, magnesium ion binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Human IDH3B Reactome UniProtKB {GO:0005739=PMID:10601238, GO:0006102=GO_REF:0000019, GO:0006099=Reactome:REACT_1785, GO:0051287=GO_REF:0000002, GO:0000287=GO_REF:0000002, GO:0004449=GO_REF:0000003, GO:0005759=Reactome:REACT_1068, GO:0006103=GO_REF:0000019, GO:0009055=PMID:10601238, GO:0044281=Reactome:REACT_111217, GO:0006734=GO_REF:0000019} O43837 "Isocitrate dehydrogenase ""NAD"" subunit beta, mitochondrial" protein 20120320 {GO:0005739=TAS, GO:0006102=IEA, GO:0006099=TAS, GO:0051287=IEA, GO:0000287=IEA, GO:0004449=IEA, GO:0005759=TAS, GO:0006103=IEA, GO:0009055=TAS, GO:0044281=TAS, GO:0006734=IEA} 2-oxoglutarate metabolic process, NADH metabolic process, isocitrate metabolic process, small molecule metabolic process, tricarboxylic acid cycle mitochondrial matrix, mitochondrion NAD binding, electron carrier activity, isocitrate dehydrogenase (NAD+) activity, magnesium ion binding Human IDH3G HPA UniProtKB {GO:0000287=GO_REF:0000002, GO:0006099=Reactome:REACT_1785, GO:0005975=PMID:9286695, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0016616=GO_REF:0000002, GO:0005739=GO_REF:0000052, GO:0006102=GO_REF:0000024, GO:0051287=GO_REF:0000002, GO:0004449=GO_REF:0000024, GO:0005759=Reactome:REACT_1068} P51553 "Isocitrate dehydrogenase ""NAD"" subunit gamma, mitochondrial" protein 20080205 {GO:0000287=IEA, GO:0006099=TAS, GO:0005975=NAS, GO:0005730=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0005524=IEA, GO:0016616=IEA, GO:0005739=IDA, GO:0006102=ISS, GO:0051287=IEA, GO:0004449=ISS, GO:0005759=TAS} carbohydrate metabolic process, isocitrate metabolic process, small molecule metabolic process, tricarboxylic acid cycle mitochondrial matrix, mitochondrion, nucleolus, nucleus ATP binding, NAD binding, isocitrate dehydrogenase (NAD+) activity, magnesium ion binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Human IDI1 Reactome UniProtKB {GO:0005739=GO_REF:0000019, GO:0006695=Reactome:REACT_9405, GO:0035634=GO_REF:0000019, GO:0016787=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0008299=GO_REF:0000037, GO:0004452=GO_REF:0000003, GO:0050992=GO_REF:0000041, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_147880, GO:0005777=PMID:17180682} Q13907 Isopentenyl-diphosphate Delta-isomerase 1 protein 20130301 {GO:0005739=IEA, GO:0006695=TAS, GO:0035634=IEA, GO:0016787=IEA, GO:0044281=TAS, GO:0008299=IEA, GO:0004452=IEA, GO:0050992=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0005777=IDA} cholesterol biosynthetic process, dimethylallyl diphosphate biosynthetic process, isoprenoid biosynthetic process, response to stilbenoid, small molecule metabolic process cytosol, mitochondrion, peroxisome hydrolase activity, isopentenyl-diphosphate delta-isomerase activity, metal ion binding Human IDI2 Reactome UniProtKB {GO:0006695=Reactome:REACT_9405, GO:0016787=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0008299=PMID:17202134, GO:0004452=PMID:17202134, GO:0050992=GO_REF:0000041, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_9517, GO:0005777=PMID:17202134} Q9BXS1 Isopentenyl-diphosphate Delta-isomerase 2 protein 20130301 {GO:0006695=TAS, GO:0016787=IEA, GO:0044281=TAS, GO:0008299=IDA, GO:0004452=IDA, GO:0050992=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0005777=IDA} cholesterol biosynthetic process, dimethylallyl diphosphate biosynthetic process, isoprenoid biosynthetic process, small molecule metabolic process cytosol, peroxisome hydrolase activity, isopentenyl-diphosphate delta-isomerase activity, metal ion binding Human IDO1 Reactome UniProtKB {GO:0006569=Reactome:REACT_916, GO:0032693=GO_REF:0000019, GO:0070233=GO_REF:0000019, GO:0046007=GO_REF:0000019, GO:0032735=GO_REF:0000019, GO:0002534=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0030485=GO_REF:0000019, GO:0005829=Reactome:REACT_11113, GO:0034641=Reactome:REACT_13, GO:0002678=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0007610=GO_REF:0000019, GO:0004833=Reactome:REACT_11113, GO:0007565=PMID:9712583, GO:0043065=GO_REF:0000019, GO:0009055=PMID:2109605, GO:0032421=GO_REF:0000019, GO:0033555=GO_REF:0000019, GO:0002666=GO_REF:0000019, GO:0019441=GO_REF:0000041, GO:0033754=GO_REF:0000003, GO:0002830=GO_REF:0000019, GO:0034276=GO_REF:0000019, GO:0020037=GO_REF:0000002} P14902 Indoleamine 2,3-dioxygenase 1 protein 20100225 {GO:0006569=TAS, GO:0032693=IEA, GO:0070233=IEA, GO:0046007=IEA, GO:0032735=IEA, GO:0002534=IEA, GO:0044281=TAS, GO:0046872=IEA, GO:0030485=IEA, GO:0005829=TAS, GO:0034641=TAS, GO:0002678=IEA, GO:0032496=IEA, GO:0007610=IEA, GO:0004833=EXP, GO:0007565=TAS, GO:0043065=IEA, GO:0009055=TAS, GO:0032421=IEA, GO:0033555=IEA, GO:0002666=IEA, GO:0019441=IEA, GO:0033754=IEA, GO:0002830=IEA, GO:0034276=IEA, GO:0020037=IEA} behavior, cellular nitrogen compound metabolic process, cytokine production involved in inflammatory response, female pregnancy, kynurenic acid biosynthetic process, multicellular organismal response to stress, negative regulation of T cell apoptotic process, negative regulation of activated T cell proliferation, negative regulation of interleukin-10 production, positive regulation of T cell tolerance induction, positive regulation of apoptotic process, positive regulation of chronic inflammatory response, positive regulation of interleukin-12 production, positive regulation of type 2 immune response, response to lipopolysaccharide, small molecule metabolic process, tryptophan catabolic process, tryptophan catabolic process to kynurenine cytosol, smooth muscle contractile fiber, stereocilium bundle electron carrier activity, heme binding, indoleamine 2,3-dioxygenase activity, metal ion binding, tryptophan 2,3-dioxygenase activity Human IDS Reactome UniProtKB {GO:0030207=Reactome:REACT_120888, GO:0005975=Reactome:REACT_474, GO:0004423=Reactome:REACT_121160, GO:0006027=Reactome:REACT_120752, GO:0044281=Reactome:REACT_111217, GO:0008484=GO_REF:0000002, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121315, GO:0046872=GO_REF:0000037, GO:0043202=Reactome:REACT_121160} P22304 Iduronate 2-sulfatase protein 20111019 {GO:0030207=TAS, GO:0005975=TAS, GO:0004423=TAS, GO:0006027=TAS, GO:0044281=TAS, GO:0008484=IEA, GO:0030204=TAS, GO:0030203=TAS, GO:0046872=IEA, GO:0043202=TAS} carbohydrate metabolic process, chondroitin sulfate catabolic process, chondroitin sulfate metabolic process, glycosaminoglycan catabolic process, glycosaminoglycan metabolic process, small molecule metabolic process lysosomal lumen iduronate-2-sulfatase activity, metal ion binding, sulfuric ester hydrolase activity Human IDUA Reactome UniProtKB {GO:0048878=GO_REF:0000019, GO:0005975=Reactome:REACT_474, GO:0030135=GO_REF:0000019, GO:0005102=GO_REF:0000019, GO:0006027=Reactome:REACT_120752, GO:0048705=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0005764=GO_REF:0000019, GO:0004553=GO_REF:0000002, GO:0030207=Reactome:REACT_120888, GO:0000902=GO_REF:0000019, GO:0003940=GO_REF:0000003, GO:0005984=PMID:2470345, GO:0030204=Reactome:REACT_121206, GO:0035108=GO_REF:0000019, GO:0030203=Reactome:REACT_121315, GO:0007040=GO_REF:0000019, GO:0043202=Reactome:REACT_121137} P35475 Alpha-L-iduronidase protein 20130301 {GO:0048878=IEA, GO:0005975=TAS, GO:0030135=IEA, GO:0005102=IEA, GO:0006027=TAS, GO:0048705=IEA, GO:0044281=TAS, GO:0005764=IEA, GO:0004553=IEA, GO:0030207=TAS, GO:0000902=IEA, GO:0003940=IEA, GO:0005984=TAS, GO:0030204=TAS, GO:0035108=IEA, GO:0030203=TAS, GO:0007040=IEA, GO:0043202=TAS} carbohydrate metabolic process, cell morphogenesis, chemical homeostasis, chondroitin sulfate catabolic process, chondroitin sulfate metabolic process, disaccharide metabolic process, glycosaminoglycan catabolic process, glycosaminoglycan metabolic process, limb morphogenesis, lysosome organization, skeletal system morphogenesis, small molecule metabolic process coated vesicle, lysosomal lumen, lysosome L-iduronidase activity, hydrolase activity, hydrolyzing O-glycosyl compounds, receptor binding Human IER2 null null {} null null null null {} null null null IER3 InterPro UniProtKB {GO:0005515=PMID:15451437, GO:0043066=GO_REF:0000002, GO:0045732=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:2001020=PMID:20467439, GO:0006915=PMID:9196025, GO:0005634=PMID:20467439, GO:0009653=PMID:9196025, GO:0050728=GO_REF:0000019, GO:0001562=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0045820=GO_REF:0000019, GO:2000377=GO_REF:0000019, GO:0003085=GO_REF:0000019} Q5ST79 Immediate early response 3, isoform CRA_b protein 20130413 {GO:0005515=IPI, GO:0043066=IEA, GO:0045732=IEA, GO:0043065=IEA, GO:2001020=IMP, GO:0006915=TAS, GO:0005634=IDA, GO:0009653=TAS, GO:0050728=IEA, GO:0001562=IEA, GO:0016021=IEA, GO:0045820=IEA, GO:2000377=IEA, GO:0003085=IEA} anatomical structure morphogenesis, apoptotic process, negative regulation of apoptotic process, negative regulation of glycolysis, negative regulation of inflammatory response, negative regulation of systemic arterial blood pressure, positive regulation of apoptotic process, positive regulation of protein catabolic process, regulation of reactive oxygen species metabolic process, regulation of response to DNA damage stimulus, response to protozoan integral to membrane, nucleus protein binding Human InterPro:IPR024829 IER3IP1 HPA UniProtKB {GO:0005794=GO_REF:0000052, GO:0005783=GO_REF:0000052, GO:0005789=GO_REF:0000039, GO:0042981=PMID:21835305, GO:0016021=GO_REF:0000037} Q9Y5U9 Immediate early response 3-interacting protein 1 protein 20080205 {GO:0005794=IDA, GO:0005783=IDA, GO:0005789=IEA, GO:0042981=IMP, GO:0016021=IEA} regulation of apoptotic process Golgi apparatus, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane Human IER5 null null {} null null null null {} null null null IER5L null null {} null null null null {} null null null IFFO1 UniProtKB UniProtKB {GO:0005882=GO_REF:0000037} Q0D2I5 Intermediate filament family orphan 1 protein 20130413 {GO:0005882=IEA} intermediate filament Human UniProtKB-KW:KW-0403 IFFO2 null null {} null null null null {} null null null IFI16 HPA UniProtKB {GO:0005515=PMID:20890285, GO:0008283=PMID:9766636, GO:0032731=PMID:21575908, GO:0005634=GO_REF:0000052, GO:0001819=PMID:22046441, GO:0002218=PMID:21575908, GO:0097202=PMID:21575908, GO:0005829=Reactome:REACT_147878, GO:0005737=GO_REF:0000052, GO:0051607=PMID:21575908, GO:0003690=PMID:7536752, GO:0006954=GO_REF:0000037, GO:0045944=PMID:21575908, GO:0030099=PMID:7536752, GO:0032481=Reactome:REACT_147841, GO:0030224=PMID:9766636, GO:0042149=PMID:21573174, GO:0045071=PMID:22291595, GO:0045824=PMID:22046441, GO:0030097=PMID:9766636, GO:0006355=GO_REF:0000029, GO:0006914=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:2000117=PMID:22046441, GO:0000122=PMID:22046441, GO:0009615=GO_REF:0000029, GO:0006351=GO_REF:0000037, GO:0071479=PMID:14654789, GO:0043392=PMID:22291595, GO:0042771=PMID:14654789, GO:0016607=PMID:19158679, GO:0072332=PMID:21573174, GO:0045087=Reactome:REACT_6802, GO:0010506=PMID:21573174, GO:0005654=PMID:14654789, GO:0045892=PMID:9642285, GO:0008134=PMID:22291595} Q16666 Gamma-interferon-inducible protein 16 protein 20101115 {GO:0005515=IPI, GO:0008283=NAS, GO:0032731=IDA, GO:0005634=IDA, GO:0001819=TAS, GO:0002218=IDA, GO:0097202=IMP, GO:0005829=TAS, GO:0005737=IDA, GO:0051607=IMP, GO:0003690=IDA, GO:0006954=IEA, GO:0045944=IMP, GO:0030099=NAS, GO:0032481=TAS, GO:0030224=IDA, GO:0042149=IDA, GO:0045071=IDA, GO:0045824=IDA, GO:0030097=NAS, GO:0006355=NAS, GO:0006914=IEA, GO:0005730=IDA, GO:2000117=IDA, GO:0000122=IMP, GO:0009615=NAS, GO:0006351=IEA, GO:0071479=IDA, GO:0043392=IDA, GO:0042771=IDA, GO:0016607=IDA, GO:0072332=IMP, GO:0045087=TAS, GO:0010506=IEP, GO:0005654=IDA, GO:0045892=IDA, GO:0008134=IDA} activation of cysteine-type endopeptidase activity, activation of innate immune response, autophagy, cell proliferation, cellular response to glucose starvation, cellular response to ionizing radiation, defense response to virus, hemopoiesis, inflammatory response, innate immune response, intrinsic apoptotic signaling pathway by p53 class mediator, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, monocyte differentiation, myeloid cell differentiation, negative regulation of DNA binding, negative regulation of cysteine-type endopeptidase activity, negative regulation of innate immune response, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, negative regulation of viral genome replication, positive regulation of cytokine production, positive regulation of interleukin-1 beta production, positive regulation of transcription from RNA polymerase II promoter, positive regulation of type I interferon production, regulation of autophagy, regulation of transcription, DNA-dependent, response to virus, transcription, DNA-dependent cytoplasm, cytosol, nuclear speck, nucleolus, nucleoplasm, nucleus double-stranded DNA binding, protein binding, transcription factor binding Human IFI27 Reactome UniProtKB {GO:0005739=PMID:18330707, GO:0003674=GO_REF:0000015, GO:0060337=Reactome:REACT_25162, GO:0006919=PMID:18330707, GO:0019221=Reactome:REACT_25229, GO:0005741=Reactome:REACT_25192, GO:0016021=GO_REF:0000029, GO:0097190=PMID:18330707} P40305 Interferon alpha-inducible protein 27, mitochondrial protein 20130228 {GO:0005739=IDA, GO:0003674=ND, GO:0060337=TAS, GO:0006919=IDA, GO:0019221=TAS, GO:0005741=TAS, GO:0016021=NAS, GO:0097190=IDA} activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic signaling pathway, cytokine-mediated signaling pathway, type I interferon-mediated signaling pathway integral to membrane, mitochondrial outer membrane, mitochondrion molecular_function Human IFI30 HPA UniProtKB {GO:0016667=PMID:10639150, GO:0030054=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0019221=Reactome:REACT_25229, GO:0048147=GO_REF:0000019, GO:0050821=GO_REF:0000019, GO:0042590=GO_REF:0000024, GO:0005576=GO_REF:0000039, GO:0005764=PMID:10639150, GO:0043231=GO_REF:0000052, GO:0019886=Reactome:REACT_121399, GO:0043202=Reactome:REACT_121326, GO:0060333=Reactome:REACT_25078} P13284 Gamma-interferon-inducible lysosomal thiol reductase protein 20101115 {GO:0016667=IMP, GO:0030054=IDA, GO:0005886=IDA, GO:0019221=TAS, GO:0048147=IEA, GO:0050821=IEA, GO:0042590=ISS, GO:0005576=IEA, GO:0005764=IDA, GO:0043231=IDA, GO:0019886=TAS, GO:0043202=TAS, GO:0060333=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class II, cytokine-mediated signaling pathway, interferon-gamma-mediated signaling pathway, negative regulation of fibroblast proliferation, protein stabilization cell junction, extracellular region, intracellular membrane-bounded organelle, lysosomal lumen, lysosome, plasma membrane oxidoreductase activity, acting on a sulfur group of donors Human IFI35 Reactome UniProtKB {GO:0005515=PMID:8954125, GO:0006955=GO_REF:0000029, GO:0060337=Reactome:REACT_25162, GO:0019221=Reactome:REACT_25229, GO:0005634=PMID:8288566, GO:0009615=GO_REF:0000029, GO:0005829=Reactome:REACT_25192} P80217 Interferon-induced 35 kDa protein protein 20130228 {GO:0005515=IPI, GO:0006955=NAS, GO:0060337=TAS, GO:0019221=TAS, GO:0005634=IDA, GO:0009615=NAS, GO:0005829=TAS} cytokine-mediated signaling pathway, immune response, response to virus, type I interferon-mediated signaling pathway cytosol, nucleus protein binding Human IFI44 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0009615=PMID:7925411} Q8TCB0 Interferon-induced protein 44 protein 20100326 {GO:0005737=IDA, GO:0009615=TAS} response to virus cytoplasm Human IFI6 Reactome UniProtKB {GO:0005739=PMID:15685448, GO:0005515=PMID:15685448, GO:0043066=PMID:15685448, GO:0006955=PMID:3017706, GO:0060337=Reactome:REACT_25162, GO:0005886=Reactome:REACT_25192, GO:0051902=PMID:15685448, GO:0019221=Reactome:REACT_25229, GO:0001836=PMID:15685448, GO:0016021=GO_REF:0000037, GO:0043154=PMID:15685448} P09912 Interferon alpha-inducible protein 6 protein 20130228 {GO:0005739=IDA, GO:0005515=IPI, GO:0043066=IMP, GO:0006955=TAS, GO:0060337=TAS, GO:0005886=TAS, GO:0051902=IMP, GO:0019221=TAS, GO:0001836=IMP, GO:0016021=IEA, GO:0043154=IMP} cytokine-mediated signaling pathway, immune response, negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of mitochondrial depolarization, release of cytochrome c from mitochondria, type I interferon-mediated signaling pathway integral to membrane, mitochondrion, plasma membrane protein binding Human IFIH1 HPA UniProtKB {GO:0005515=PMID:16127453, GO:0003725=PMID:17079289, GO:0032728=PMID:17079289, GO:0003727=PMID:19656871, GO:0034344=PMID:21616437, GO:0016925=PMID:21156324, GO:0032727=PMID:17079289, GO:0004386=GO_REF:0000037, GO:0042981=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0009615=PMID:21616437, GO:0003677=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_25398, GO:0005737=GO_REF:0000052, GO:0039528=PMID:21616437, GO:0045087=Reactome:REACT_6802, GO:0019048=GO_REF:0000037, GO:0043021=PMID:19881509, GO:0009597=PMID:17079289, GO:0008270=PMID:19380577, GO:0032480=Reactome:REACT_25271} Q9BYX4 Interferon-induced helicase C domain-containing protein 1 protein 20080818 {GO:0005515=IPI, GO:0003725=TAS, GO:0032728=TAS, GO:0003727=IDA, GO:0034344=TAS, GO:0016925=IDA, GO:0032727=TAS, GO:0004386=IEA, GO:0042981=IEA, GO:0005634=IEA, GO:0009615=TAS, GO:0003677=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0039528=TAS, GO:0045087=TAS, GO:0019048=IEA, GO:0043021=IPI, GO:0009597=TAS, GO:0008270=IDA, GO:0032480=TAS} cytoplasmic pattern recognition receptor signaling pathway in response to virus, detection of virus, innate immune response, negative regulation of type I interferon production, positive regulation of interferon-alpha production, positive regulation of interferon-beta production, protein sumoylation, regulation of apoptotic process, regulation of type III interferon production, response to virus, virus-host interaction cytoplasm, cytosol, nucleus ATP binding, DNA binding, double-stranded RNA binding, helicase activity, protein binding, ribonucleoprotein complex binding, single-stranded RNA binding, zinc ion binding Human IFIT1 BHF-UCL UniProtKB {GO:0032091=PMID:19416887, GO:0050688=GO_REF:0000002, GO:0005515=PMID:19416887, GO:0050689=PMID:19416887, GO:0019060=PMID:19008854, GO:0003723=PMID:21642987, GO:0019221=Reactome:REACT_25229, GO:0051097=PMID:19008854, GO:0009615=PMID:19416887, GO:0005829=Reactome:REACT_115684, GO:0071360=PMID:19008854, GO:0051607=GO_REF:0000037, GO:0005737=PMID:19008854, GO:0060337=Reactome:REACT_25162, GO:0071357=PMID:19008854, GO:0045070=PMID:19416887, GO:0045071=PMID:19008854} P09914 Interferon-induced protein with tetratricopeptide repeats 1 protein 20110119 {GO:0032091=IDA, GO:0050688=IEA, GO:0005515=IPI, GO:0050689=IDA, GO:0019060=IDA, GO:0003723=IDA, GO:0019221=TAS, GO:0051097=IDA, GO:0009615=IDA, GO:0005829=TAS, GO:0071360=IDA, GO:0051607=IEA, GO:0005737=IDA, GO:0060337=TAS, GO:0071357=IDA, GO:0045070=IDA, GO:0045071=IMP} cellular response to exogenous dsRNA, cellular response to type I interferon, cytokine-mediated signaling pathway, defense response to virus, intracellular transport of viral proteins in host cell, negative regulation of defense response to virus by host, negative regulation of helicase activity, negative regulation of protein binding, negative regulation of viral genome replication, positive regulation of viral genome replication, regulation of defense response to virus, response to virus, type I interferon-mediated signaling pathway cytoplasm, cytosol RNA binding, protein binding Human IFIT1B null null {} null null null null {} null null null IFIT2 BHF-UCL UniProtKB {GO:0005515=PMID:19416887, GO:0032091=PMID:19416887, GO:0043065=PMID:21190939, GO:0035457=GO_REF:0000019, GO:0005783=PMID:21190939, GO:0003723=GO_REF:0000037, GO:0019221=Reactome:REACT_25229, GO:0009615=PMID:19416887, GO:0005829=Reactome:REACT_25192, GO:0051607=GO_REF:0000037, GO:0005737=PMID:21190939, GO:0008637=PMID:21190939, GO:0060337=Reactome:REACT_25162} P09913 Interferon-induced protein with tetratricopeptide repeats 2 protein 20110119 {GO:0005515=IPI, GO:0032091=IDA, GO:0043065=IDA, GO:0035457=IEA, GO:0005783=IDA, GO:0003723=IEA, GO:0019221=TAS, GO:0009615=IDA, GO:0005829=TAS, GO:0051607=IEA, GO:0005737=IDA, GO:0008637=TAS, GO:0060337=TAS} apoptotic mitochondrial changes, cellular response to interferon-alpha, cytokine-mediated signaling pathway, defense response to virus, negative regulation of protein binding, positive regulation of apoptotic process, response to virus, type I interferon-mediated signaling pathway cytoplasm, cytosol, endoplasmic reticulum RNA binding, protein binding Human IFIT3 IntAct UniProtKB {GO:0005515=PMID:21642987, GO:0043066=PMID:21190939, GO:0008285=PMID:17050680, GO:0035457=GO_REF:0000002, GO:0019221=Reactome:REACT_25229, GO:0009615=PMID:21642987, GO:0005829=Reactome:REACT_25192, GO:0042802=PMID:21642987, GO:0005739=PMID:21813773, GO:0003674=GO_REF:0000015, GO:0051607=GO_REF:0000037, GO:0005737=PMID:18706081, GO:0060337=Reactome:REACT_25162} O14879 Interferon-induced protein with tetratricopeptide repeats 3 protein 20130415 {GO:0005515=IPI, GO:0043066=IDA, GO:0008285=IDA, GO:0035457=IEA, GO:0019221=TAS, GO:0009615=IMP, GO:0005829=TAS, GO:0042802=IPI, GO:0005739=IDA, GO:0003674=ND, GO:0051607=IEA, GO:0005737=IDA, GO:0060337=TAS} cellular response to interferon-alpha, cytokine-mediated signaling pathway, defense response to virus, negative regulation of apoptotic process, negative regulation of cell proliferation, response to virus, type I interferon-mediated signaling pathway cytoplasm, cytosol, mitochondrion identical protein binding, molecular_function, protein binding Human UniProtKB:O14879 IFIT5 UniProtKB UniProtKB {GO:0051607=PMID:23334420, GO:0003727=PMID:23334420, GO:0000049=PMID:23317505, GO:0003723=PMID:21642987, GO:0045087=GO_REF:0000037, GO:0045177=PMID:23317505, GO:0032587=PMID:23317505, GO:0015629=PMID:23317505} Q13325 Interferon-induced protein with tetratricopeptide repeats 5 protein 20130125 {GO:0051607=IMP, GO:0003727=IDA, GO:0000049=IDA, GO:0003723=IDA, GO:0045087=IEA, GO:0045177=IDA, GO:0032587=IDA, GO:0015629=IDA} defense response to virus, innate immune response actin cytoskeleton, apical part of cell, ruffle membrane RNA binding, single-stranded RNA binding, tRNA binding Human IFITM1 Reactome UniProtKB {GO:0005515=PMID:2398277, GO:0030336=PMID:20838853, GO:0008285=PMID:20838853, GO:0005886=Reactome:REACT_25192, GO:0035456=PMID:21253575, GO:0019221=Reactome:REACT_25229, GO:0035455=PMID:22479637, GO:0009615=PMID:22479637, GO:0045669=PMID:22634173, GO:0051607=GO_REF:0000037, GO:0060337=Reactome:REACT_25162, GO:0001503=GO_REF:0000037, GO:0046597=PMID:21253575, GO:0050776=Reactome:REACT_11152, GO:0005057=PMID:7559564, GO:0016021=GO_REF:0000037, GO:0034341=PMID:21253575, GO:0007166=PMID:7559564, GO:0045071=PMID:21253575} P13164 Interferon-induced transmembrane protein 1 protein 20130228 {GO:0005515=IPI, GO:0030336=IMP, GO:0008285=IMP, GO:0005886=TAS, GO:0035456=IDA, GO:0019221=TAS, GO:0035455=IDA, GO:0009615=IDA, GO:0045669=IMP, GO:0051607=IEA, GO:0060337=TAS, GO:0001503=IEA, GO:0046597=IDA, GO:0050776=TAS, GO:0005057=TAS, GO:0016021=IEA, GO:0034341=IDA, GO:0007166=TAS, GO:0045071=IDA} cell surface receptor signaling pathway, cytokine-mediated signaling pathway, defense response to virus, negative regulation of cell migration, negative regulation of cell proliferation, negative regulation of viral entry into host cell, negative regulation of viral genome replication, ossification, positive regulation of osteoblast differentiation, regulation of immune response, response to interferon-alpha, response to interferon-beta, response to interferon-gamma, response to virus, type I interferon-mediated signaling pathway integral to membrane, plasma membrane protein binding, receptor signaling protein activity Human IFITM2 Reactome UniProtKB {GO:0005886=Reactome:REACT_25192, GO:0035456=PMID:21253575, GO:0035455=PMID:22479637, GO:0019221=Reactome:REACT_25229, GO:0009615=PMID:22479637, GO:0009607=GO_REF:0000002, GO:0051607=GO_REF:0000037, GO:0006955=PMID:1906403, GO:0060337=Reactome:REACT_25162, GO:0046597=PMID:21253575, GO:0016021=GO_REF:0000037, GO:0034341=PMID:21253575, GO:0045071=PMID:21253575} Q01629 Interferon-induced transmembrane protein 2 protein 20130228 {GO:0005886=TAS, GO:0035456=IDA, GO:0035455=IDA, GO:0019221=TAS, GO:0009615=IDA, GO:0009607=IEA, GO:0051607=IEA, GO:0006955=TAS, GO:0060337=TAS, GO:0046597=IDA, GO:0016021=IEA, GO:0034341=IDA, GO:0045071=IDA} cytokine-mediated signaling pathway, defense response to virus, immune response, negative regulation of viral entry into host cell, negative regulation of viral genome replication, response to biotic stimulus, response to interferon-alpha, response to interferon-beta, response to interferon-gamma, response to virus, type I interferon-mediated signaling pathway integral to membrane, plasma membrane Human IFITM3 LIFEdb UniProtKB {GO:0005886=GO_REF:0000054, GO:0035456=PMID:21253575, GO:0019221=Reactome:REACT_25229, GO:0035455=PMID:22479637, GO:0032897=PMID:20943977, GO:0005765=GO_REF:0000039, GO:0009615=PMID:22479637, GO:0009607=GO_REF:0000002, GO:0051607=GO_REF:0000037, GO:0006955=PMID:1906403, GO:0060337=Reactome:REACT_25162, GO:0046597=PMID:21253575, GO:0031902=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0034341=PMID:21253575, GO:0045071=PMID:21253575} Q01628 Interferon-induced transmembrane protein 3 protein 20100607 {GO:0005886=IDA, GO:0035456=IDA, GO:0019221=TAS, GO:0035455=IDA, GO:0032897=IDA, GO:0005765=IEA, GO:0009615=IDA, GO:0009607=IEA, GO:0051607=IEA, GO:0006955=TAS, GO:0060337=TAS, GO:0046597=IDA, GO:0031902=IEA, GO:0016021=IEA, GO:0034341=IDA, GO:0045071=IDA} cytokine-mediated signaling pathway, defense response to virus, immune response, negative regulation of viral entry into host cell, negative regulation of viral genome replication, negative regulation of viral transcription, response to biotic stimulus, response to interferon-alpha, response to interferon-beta, response to interferon-gamma, response to virus, type I interferon-mediated signaling pathway integral to membrane, late endosome membrane, lysosomal membrane, plasma membrane Human IFLTD1 ENSEMBL UniProtKB {GO:0005882=GO_REF:0000037, GO:0005737=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:0005198=GO_REF:0000002, GO:0005635=GO_REF:0000019} Q8N9Z9 Intermediate filament tail domain-containing protein 1 protein 20130413 {GO:0005882=IEA, GO:0005737=IEA, GO:0008283=IEA, GO:0005198=IEA, GO:0005635=IEA} cell proliferation cytoplasm, intermediate filament, nuclear envelope structural molecule activity Human Ensembl:ENSMUSP00000107337 IFNA1 Reactome UniProtKB {GO:0051607=GO_REF:0000037, GO:0060337=Reactome:REACT_25162, GO:0060338=Reactome:REACT_25216, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0005132=PMID:4057246, GO:0019221=Reactome:REACT_25229, GO:0005576=Reactome:REACT_25401, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037} P01562 Interferon alpha-1/13 protein 20130228 {GO:0051607=IEA, GO:0060337=TAS, GO:0060338=TAS, GO:0007596=TAS, GO:0045087=TAS, GO:0005132=TAS, GO:0019221=TAS, GO:0005576=TAS, GO:0005615=IEA, GO:0005125=IEA} blood coagulation, cytokine-mediated signaling pathway, defense response to virus, innate immune response, regulation of type I interferon-mediated signaling pathway, type I interferon-mediated signaling pathway extracellular region, extracellular space cytokine activity, interferon-alpha/beta receptor binding Human IFNA16 Reactome UniProtKB {GO:0051607=GO_REF:0000037, GO:0060337=Reactome:REACT_25162, GO:0060338=Reactome:REACT_25216, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0005132=PMID:6548765, GO:0019221=Reactome:REACT_25229, GO:0005576=Reactome:REACT_25401, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037} P05015 Interferon alpha-16 protein 20130228 {GO:0051607=IEA, GO:0060337=TAS, GO:0060338=TAS, GO:0007596=TAS, GO:0045087=TAS, GO:0005132=TAS, GO:0019221=TAS, GO:0005576=TAS, GO:0005615=IEA, GO:0005125=IEA} blood coagulation, cytokine-mediated signaling pathway, defense response to virus, innate immune response, regulation of type I interferon-mediated signaling pathway, type I interferon-mediated signaling pathway extracellular region, extracellular space cytokine activity, interferon-alpha/beta receptor binding Human IFNA2 BHF-UCL UniProtKB {GO:0005515=PMID:7759950, GO:2000552=PMID:20554961, GO:2000666=PMID:20554961, GO:0042517=PMID:22783022, GO:0005132=PMID:6158094, GO:0019221=Reactome:REACT_25229, GO:2000663=PMID:20554961, GO:0007267=PMID:10477584, GO:0005576=Reactome:REACT_25401, GO:0006917=PMID:10477584, GO:0005125=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0051607=PMID:22783022, GO:0060337=Reactome:REACT_25162, GO:0006954=PMID:10477584, GO:0060338=Reactome:REACT_25216, GO:0046597=PMID:22783022, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0010629=PMID:20554961, GO:0045581=PMID:20554961, GO:0045892=PMID:20554961, GO:0007166=PMID:6158094} P01563 Interferon alpha-2 protein 20121122 {GO:0005515=IPI, GO:2000552=IDA, GO:2000666=IDA, GO:0042517=IDA, GO:0005132=TAS, GO:0019221=TAS, GO:2000663=IDA, GO:0007267=TAS, GO:0005576=TAS, GO:0006917=TAS, GO:0005125=IEA, GO:0005615=IEA, GO:0051607=IDA, GO:0060337=TAS, GO:0006954=TAS, GO:0060338=TAS, GO:0046597=IDA, GO:0007596=TAS, GO:0045087=TAS, GO:0010629=IDA, GO:0045581=IDA, GO:0045892=IDA, GO:0007166=TAS} blood coagulation, cell surface receptor signaling pathway, cell-cell signaling, cytokine-mediated signaling pathway, defense response to virus, induction of apoptosis, inflammatory response, innate immune response, negative regulation of T cell differentiation, negative regulation of T-helper 2 cell cytokine production, negative regulation of gene expression, negative regulation of interleukin-13 secretion, negative regulation of interleukin-5 secretion, negative regulation of transcription, DNA-dependent, negative regulation of viral entry into host cell, positive regulation of tyrosine phosphorylation of Stat3 protein, regulation of type I interferon-mediated signaling pathway, type I interferon-mediated signaling pathway extracellular region, extracellular space cytokine activity, interferon-alpha/beta receptor binding, protein binding Human IFNA5 Reactome UniProtKB {GO:0051607=GO_REF:0000037, GO:0060337=Reactome:REACT_25162, GO:0060338=Reactome:REACT_25216, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0019221=Reactome:REACT_25229, GO:0005576=Reactome:REACT_25401, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037, GO:0005126=GO_REF:0000002} P01569 Interferon alpha-5 protein 20130228 {GO:0051607=IEA, GO:0060337=TAS, GO:0060338=TAS, GO:0007596=TAS, GO:0045087=TAS, GO:0019221=TAS, GO:0005576=TAS, GO:0005615=IEA, GO:0005125=IEA, GO:0005126=IEA} blood coagulation, cytokine-mediated signaling pathway, defense response to virus, innate immune response, regulation of type I interferon-mediated signaling pathway, type I interferon-mediated signaling pathway extracellular region, extracellular space cytokine activity, cytokine receptor binding Human IFNA8 Reactome UniProtKB {GO:0051607=GO_REF:0000037, GO:0060337=Reactome:REACT_25162, GO:0060338=Reactome:REACT_25216, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0019221=Reactome:REACT_25229, GO:0005576=Reactome:REACT_25401, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037, GO:0005126=GO_REF:0000002} P32881 Interferon alpha-8 protein 20130228 {GO:0051607=IEA, GO:0060337=TAS, GO:0060338=TAS, GO:0007596=TAS, GO:0045087=TAS, GO:0019221=TAS, GO:0005576=TAS, GO:0005615=IEA, GO:0005125=IEA, GO:0005126=IEA} blood coagulation, cytokine-mediated signaling pathway, defense response to virus, innate immune response, regulation of type I interferon-mediated signaling pathway, type I interferon-mediated signaling pathway extracellular region, extracellular space cytokine activity, cytokine receptor binding Human IFNAR1 Reactome UniProtKB {GO:0032729=GO_REF:0000019, GO:0005886=Reactome:REACT_25401, GO:0019221=Reactome:REACT_25229, GO:0045351=GO_REF:0000019, GO:0009615=PMID:2153461, GO:0007259=PMID:7665574, GO:0042110=GO_REF:0000019, GO:0051607=GO_REF:0000019, GO:0060337=Reactome:REACT_25162, GO:0060338=Reactome:REACT_25216, GO:0004905=PMID:7665574, GO:0005887=PMID:8181059, GO:0004904=GO_REF:0000019, GO:0007166=PMID:7665574} P17181 Interferon alpha/beta receptor 1 protein 20100614 {GO:0032729=IEA, GO:0005886=TAS, GO:0019221=TAS, GO:0045351=IEA, GO:0009615=TAS, GO:0007259=TAS, GO:0042110=IEA, GO:0051607=IEA, GO:0060337=TAS, GO:0060338=TAS, GO:0004905=TAS, GO:0005887=TAS, GO:0004904=IEA, GO:0007166=TAS} JAK-STAT cascade, T cell activation, cell surface receptor signaling pathway, cytokine-mediated signaling pathway, defense response to virus, positive regulation of interferon-gamma production, regulation of type I interferon-mediated signaling pathway, response to virus, type I interferon biosynthetic process, type I interferon-mediated signaling pathway integral to plasma membrane, plasma membrane interferon receptor activity, type I interferon receptor activity Human IFNAR2 IntAct UniProtKB {GO:0005515=PMID:17923090, GO:0006357=GO_REF:0000019, GO:0019901=PMID:7759950, GO:0005886=Reactome:REACT_25401, GO:0008283=GO_REF:0000019, GO:0035455=PMID:7759950, GO:0019221=Reactome:REACT_25229, GO:0005576=PMID:7588638, GO:0009615=PMID:7588638, GO:0005615=GO_REF:0000019, GO:0007259=PMID:7588638, GO:0060337=Reactome:REACT_25162, GO:0060338=Reactome:REACT_25216, GO:0004905=PMID:7759950, GO:0005887=PMID:7759950, GO:0007166=PMID:8798579} P48551 Interferon alpha/beta receptor 2 protein 20130415 {GO:0005515=IPI, GO:0006357=IEA, GO:0019901=IPI, GO:0005886=TAS, GO:0008283=IEA, GO:0035455=IDA, GO:0019221=TAS, GO:0005576=TAS, GO:0009615=TAS, GO:0005615=IEA, GO:0007259=TAS, GO:0060337=TAS, GO:0060338=TAS, GO:0004905=IDA, GO:0005887=IDA, GO:0007166=TAS} JAK-STAT cascade, cell proliferation, cell surface receptor signaling pathway, cytokine-mediated signaling pathway, regulation of transcription from RNA polymerase II promoter, regulation of type I interferon-mediated signaling pathway, response to interferon-alpha, response to virus, type I interferon-mediated signaling pathway extracellular region, extracellular space, integral to plasma membrane, plasma membrane protein binding, protein kinase binding, type I interferon receptor activity Human UniProtKB:Q92793 IFNB1 BHF-UCL UniProtKB {GO:2000552=PMID:20554961, GO:0008285=PMID:3872918, GO:0005132=PMID:2414376, GO:0019221=Reactome:REACT_25229, GO:0005615=GO_REF:0000019, GO:0051607=PMID:19416887, GO:0060337=Reactome:REACT_25162, GO:0030101=PMID:11987821, GO:0060338=Reactome:REACT_25216, GO:0042100=PMID:3135963, GO:0045944=PMID:19008854, GO:0006959=GO_REF:0000019, GO:0045581=PMID:20554961, GO:0042742=GO_REF:0000019, GO:0045071=PMID:19008854, GO:0006919=PMID:11337497, GO:0003714=PMID:16873258, GO:0032897=PMID:16873258, GO:0005576=Reactome:REACT_25401, GO:0006917=PMID:11337497, GO:0009615=PMID:12120696, GO:0045343=PMID:8805651, GO:0005125=GO_REF:0000019, GO:0002250=GO_REF:0000019, GO:0071360=PMID:19416887, GO:0045089=PMID:11987821, GO:0046597=PMID:10963806, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0007166=PMID:10640778} P01574 Interferon beta protein 20110119 {GO:2000552=IDA, GO:0008285=NAS, GO:0005132=NAS, GO:0019221=TAS, GO:0005615=IEA, GO:0051607=IDA, GO:0060337=TAS, GO:0030101=NAS, GO:0060338=TAS, GO:0042100=NAS, GO:0045944=IDA, GO:0006959=IEA, GO:0045581=IDA, GO:0042742=IEA, GO:0045071=IDA, GO:0006919=IDA, GO:0003714=IDA, GO:0032897=IDA, GO:0005576=TAS, GO:0006917=IDA, GO:0009615=NAS, GO:0045343=NAS, GO:0005125=IEA, GO:0002250=IEA, GO:0071360=IMP, GO:0045089=NAS, GO:0046597=NAS, GO:0007596=TAS, GO:0045087=TAS, GO:0007166=TAS} B cell proliferation, activation of cysteine-type endopeptidase activity involved in apoptotic process, adaptive immune response, blood coagulation, cell surface receptor signaling pathway, cellular response to exogenous dsRNA, cytokine-mediated signaling pathway, defense response to bacterium, defense response to virus, humoral immune response, induction of apoptosis, innate immune response, natural killer cell activation, negative regulation of T cell differentiation, negative regulation of T-helper 2 cell cytokine production, negative regulation of cell proliferation, negative regulation of viral entry into host cell, negative regulation of viral genome replication, negative regulation of viral transcription, positive regulation of innate immune response, positive regulation of transcription from RNA polymerase II promoter, regulation of MHC class I biosynthetic process, regulation of type I interferon-mediated signaling pathway, response to virus, type I interferon-mediated signaling pathway extracellular region, extracellular space cytokine activity, interferon-alpha/beta receptor binding, transcription corepressor activity Human IFNE UniProtKB UniProtKB {GO:0051607=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037, GO:0005126=GO_REF:0000002} Q86WN2 Interferon epsilon protein 20130413 {GO:0051607=IEA, GO:0005615=IEA, GO:0005125=IEA, GO:0005126=IEA} defense response to virus extracellular space cytokine activity, cytokine receptor binding Human UniProtKB-KW:KW-0051 IFNG BHF-UCL UniProtKB {GO:0051712=PMID:7544003, GO:0019221=Reactome:REACT_25229, GO:0005615=GO_REF:0000019, GO:0030968=GO_REF:0000019, GO:0045348=GO_REF:0000019, GO:0060334=Reactome:REACT_24980, GO:0051607=GO_REF:0000019, GO:0072308=GO_REF:0000024, GO:0044130=GO_REF:0000019, GO:0071351=GO_REF:0000019, GO:0042742=GO_REF:0000019, GO:0000060=PMID:15604419, GO:0060333=Reactome:REACT_25078, GO:0045410=GO_REF:0000019, GO:0032760=GO_REF:0000019, GO:0030593=GO_REF:0000019, GO:0042832=GO_REF:0000019, GO:0000122=GO_REF:0000024, GO:0005125=GO_REF:0000019, GO:0045785=GO_REF:0000019, GO:0032224=GO_REF:0000019, GO:0045084=GO_REF:0000019, GO:0002026=GO_REF:0000019, GO:0048304=GO_REF:0000019, GO:0009897=GO_REF:0000019, GO:0045080=GO_REF:0000019, GO:0001781=GO_REF:0000019, GO:0060559=PMID:9282826, GO:0051044=PMID:18373975, GO:0005133=GO_REF:0000002, GO:0060557=PMID:9282826, GO:0060550=PMID:9282826, GO:0006928=PMID:10477596, GO:0032735=PMID:7605994, GO:0060552=PMID:9282826, GO:0033141=PMID:21268089, GO:0045429=PMID:8383325, GO:0019882=GO_REF:0000019, GO:0050718=GO_REF:0000019, GO:0006959=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0042102=GO_REF:0000019, GO:0007050=PMID:16942485, GO:0002302=GO_REF:0000019, GO:0031642=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:2000309=PMID:16220542, GO:0042511=PMID:15604419, GO:0006915=PMID:7828849, GO:0045672=PMID:16220542, GO:0032747=PMID:20027291, GO:0002053=GO_REF:0000024, GO:0048662=PMID:16942485, GO:0005576=PMID:20041150, GO:0003340=GO_REF:0000024, GO:0009615=PMID:16280321, GO:0032700=PMID:18501882, GO:0002250=GO_REF:0000019, GO:0071222=GO_REF:0000019, GO:0050796=PMID:8383325, GO:0045666=GO_REF:0000019, GO:0034393=PMID:16942485, GO:0007166=PMID:10477596} P01579 Interferon gamma protein 20110223 {GO:0051712=IDA, GO:0019221=TAS, GO:0005615=IEA, GO:0030968=IEA, GO:0045348=IEA, GO:0060334=TAS, GO:0051607=IEA, GO:0072308=ISS, GO:0044130=IEA, GO:0071351=IEA, GO:0042742=IEA, GO:0000060=IDA, GO:0060333=TAS, GO:0045410=IEA, GO:0032760=IEA, GO:0030593=IEA, GO:0042832=IEA, GO:0000122=ISS, GO:0005125=IEA, GO:0045785=IEA, GO:0032224=IEA, GO:0045084=IEA, GO:0002026=IEA, GO:0048304=IEA, GO:0009897=IEA, GO:0045080=IEA, GO:0001781=IEA, GO:0060559=IDA, GO:0051044=IDA, GO:0005133=IEA, GO:0060557=IDA, GO:0060550=IDA, GO:0006928=TAS, GO:0032735=IDA, GO:0060552=IDA, GO:0033141=NAS, GO:0045429=IDA, GO:0019882=IEA, GO:0050718=IEA, GO:0006959=IEA, GO:0045944=IEA, GO:0042102=IEA, GO:0007050=IDA, GO:0002302=IEA, GO:0031642=IEA, GO:0042493=IEA, GO:2000309=IDA, GO:0042511=IDA, GO:0006915=IGI, GO:0045672=IDA, GO:0032747=IDA, GO:0002053=ISS, GO:0048662=IDA, GO:0005576=IDA, GO:0003340=ISS, GO:0009615=IDA, GO:0032700=IDA, GO:0002250=IEA, GO:0071222=IEA, GO:0050796=IDA, GO:0045666=IEA, GO:0034393=IDA, GO:0007166=TAS} CD8-positive, alpha-beta T cell differentiation involved in immune response, adaptive immune response, antigen processing and presentation, apoptotic process, cell cycle arrest, cell surface receptor signaling pathway, cellular component movement, cellular response to interleukin-18, cellular response to lipopolysaccharide, cytokine-mediated signaling pathway, defense response to bacterium, defense response to protozoan, defense response to virus, endoplasmic reticulum unfolded protein response, humoral immune response, interferon-gamma-mediated signaling pathway, negative regulation of growth of symbiont in host, negative regulation of interleukin-17 production, negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis, negative regulation of metanephric nephron tubule epithelial cell differentiation, negative regulation of myelination, negative regulation of smooth muscle cell proliferation, negative regulation of transcription from RNA polymerase II promoter, neutrophil apoptotic process, neutrophil chemotaxis, positive regulation of MHC class II biosynthetic process, positive regulation of T cell proliferation, positive regulation of calcidiol 1-monooxygenase activity, positive regulation of cell adhesion, positive regulation of chemokine biosynthetic process, positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity, positive regulation of fructose 1,6-bisphosphate metabolic process, positive regulation of interleukin-1 beta secretion, positive regulation of interleukin-12 biosynthetic process, positive regulation of interleukin-12 production, positive regulation of interleukin-23 production, positive regulation of interleukin-6 biosynthetic process, positive regulation of isotype switching to IgG isotypes, positive regulation of killing of cells of other organism, positive regulation of membrane protein ectodomain proteolysis, positive regulation of mesenchymal cell proliferation, positive regulation of neuron differentiation, positive regulation of nitric oxide biosynthetic process, positive regulation of osteoclast differentiation, positive regulation of peptidyl-serine phosphorylation of STAT protein, positive regulation of smooth muscle cell apoptotic process, positive regulation of synaptic transmission, cholinergic, positive regulation of transcription from RNA polymerase II promoter, positive regulation of tumor necrosis factor (ligand) superfamily member 11 production, positive regulation of tumor necrosis factor production, positive regulation of tyrosine phosphorylation of Stat1 protein, positive regulation of vitamin D biosynthetic process, protein import into nucleus, translocation, regulation of insulin secretion, regulation of interferon-gamma-mediated signaling pathway, regulation of the force of heart contraction, response to drug, response to virus external side of plasma membrane, extracellular region, extracellular space cytokine activity, interferon-gamma receptor binding Human IFNGR1 InterPro UniProtKB {GO:0060334=Reactome:REACT_24980, GO:0007165=PMID:2971451, GO:0019955=GO_REF:0000002, GO:0005886=Reactome:REACT_25369, GO:0016020=GO_REF:0000002, GO:0005887=PMID:2971451, GO:0004906=PMID:2971451, GO:0019221=Reactome:REACT_25229, GO:0009615=PMID:2954953, GO:0060333=Reactome:REACT_25078} Q5TFD1 Interferon gamma receptor 1 protein 20130413 {GO:0060334=TAS, GO:0007165=TAS, GO:0019955=IEA, GO:0005886=TAS, GO:0016020=IEA, GO:0005887=TAS, GO:0004906=TAS, GO:0019221=TAS, GO:0009615=TAS, GO:0060333=TAS} cytokine-mediated signaling pathway, interferon-gamma-mediated signaling pathway, regulation of interferon-gamma-mediated signaling pathway, response to virus, signal transduction integral to plasma membrane, membrane, plasma membrane cytokine binding, interferon-gamma receptor activity Human InterPro:IPR008355 IFNGR2 Reactome UniProtKB {GO:0060334=Reactome:REACT_24980, GO:0005886=Reactome:REACT_25369, GO:0005887=PMID:8910544, GO:0004906=PMID:9616207, GO:0005783=PMID:16780588, GO:0019221=Reactome:REACT_25229, GO:0009615=PMID:8124716, GO:0007166=PMID:9616207, GO:0060333=Reactome:REACT_25078} P38484 Interferon gamma receptor 2 protein 20100426 {GO:0060334=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0004906=TAS, GO:0005783=IDA, GO:0019221=TAS, GO:0009615=TAS, GO:0007166=TAS, GO:0060333=TAS} cell surface receptor signaling pathway, cytokine-mediated signaling pathway, interferon-gamma-mediated signaling pathway, regulation of interferon-gamma-mediated signaling pathway, response to virus endoplasmic reticulum, integral to plasma membrane, plasma membrane interferon-gamma receptor activity Human IFNW1 PINC UniProtKB {GO:0051607=GO_REF:0000037, GO:0007050=PMID:10835682, GO:0009615=PMID:1647209, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037, GO:0005126=GO_REF:0000002} P05000 Interferon omega-1 protein 20030904 {GO:0051607=IEA, GO:0007050=TAS, GO:0009615=TAS, GO:0005615=IEA, GO:0005125=IEA, GO:0005126=IEA} cell cycle arrest, defense response to virus, response to virus extracellular space cytokine activity, cytokine receptor binding Human IFRD1 PINC UniProtKB {GO:0042692=GO_REF:0000019, GO:0007518=PMID:7756174, GO:0007527=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0005634=GO_REF:0000019} O00458 Interferon-related developmental regulator 1 protein 20030904 {GO:0042692=IEA, GO:0007518=TAS, GO:0007527=IEA, GO:0007275=IEA, GO:0005634=IEA} adult somatic muscle development, multicellular organismal development, muscle cell differentiation, myoblast fate determination nucleus Human IFRD2 IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q12894 Interferon-related developmental regulator 2 protein 20130415 {GO:0005515=IPI, GO:0003674=ND, GO:0005575=ND} cellular_component molecular_function, protein binding Human UniProtKB:Q9Y6K5 IFT122 HPA UniProtKB {GO:0005515=PMID:22190034, GO:0010172=GO_REF:0000024, GO:0035050=GO_REF:0000024, GO:0060830=GO_REF:0000019, GO:0001843=GO_REF:0000024, GO:0045879=GO_REF:0000024, GO:0072372=GO_REF:0000024, GO:0048593=GO_REF:0000024, GO:0060831=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0060271=GO_REF:0000024, GO:0030991=PMID:20889716, GO:0032391=GO_REF:0000024, GO:0060173=GO_REF:0000024, GO:0005932=GO_REF:0000039, GO:0035721=GO_REF:0000024, GO:0042733=GO_REF:0000019} Q9HBG6 Intraflagellar transport protein 122 homolog protein 20111111 {GO:0005515=IPI, GO:0010172=ISS, GO:0035050=ISS, GO:0060830=IEA, GO:0001843=ISS, GO:0045879=ISS, GO:0072372=ISS, GO:0048593=ISS, GO:0060831=IEA, GO:0005737=IDA, GO:0060271=ISS, GO:0030991=IDA, GO:0032391=ISS, GO:0060173=ISS, GO:0005932=IEA, GO:0035721=ISS, GO:0042733=IEA} camera-type eye morphogenesis, ciliary receptor clustering involved in smoothened signaling pathway, cilium morphogenesis, embryonic body morphogenesis, embryonic digit morphogenesis, embryonic heart tube development, intraflagellar retrograde transport, limb development, negative regulation of smoothened signaling pathway, neural tube closure, smoothened signaling pathway involved in dorsal/ventral neural tube patterning cytoplasm, intraflagellar transport particle A, microtubule basal body, photoreceptor connecting cilium, primary cilium protein binding Human IFT140 UniProtKB UniProtKB {GO:0042384=GO_REF:0000019, GO:0030991=PMID:20889716, GO:0032391=GO_REF:0000019, GO:0035085=GO_REF:0000019, GO:0036064=PMID:22503633} Q96RY7 Intraflagellar transport protein 140 homolog protein 20130222 {GO:0042384=IEA, GO:0030991=IDA, GO:0032391=IEA, GO:0035085=IEA, GO:0036064=IDA} cilium assembly cilium axoneme, cilium basal body, intraflagellar transport particle A, photoreceptor connecting cilium Human IFT172 UniProtKB UniProtKB {GO:0042384=GO_REF:0000024, GO:0005929=GO_REF:0000024, GO:0007368=GO_REF:0000019, GO:0016485=GO_REF:0000019, GO:0009953=GO_REF:0000019, GO:0007224=GO_REF:0000019, GO:0001841=GO_REF:0000019} Q9UG01 Intraflagellar transport protein 172 homolog protein 20080418 {GO:0042384=ISS, GO:0005929=ISS, GO:0007368=IEA, GO:0016485=IEA, GO:0009953=IEA, GO:0007224=IEA, GO:0001841=IEA} cilium assembly, determination of left/right symmetry, dorsal/ventral pattern formation, neural tube formation, protein processing, smoothened signaling pathway cilium Human UniProtKB:Q6VH22 IFT20 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0005929=GO_REF:0000019, GO:0051642=GO_REF:0000019, GO:0005794=GO_REF:0000039, GO:0005814=GO_REF:0000039, GO:0030030=GO_REF:0000037, GO:0044292=GO_REF:0000019, GO:0030992=GO_REF:0000019, GO:0005932=GO_REF:0000039} Q8IY31 Intraflagellar transport protein 20 homolog protein 20130415 {GO:0005515=IPI, GO:0005929=IEA, GO:0051642=IEA, GO:0005794=IEA, GO:0005814=IEA, GO:0030030=IEA, GO:0044292=IEA, GO:0030992=IEA, GO:0005932=IEA} cell projection organization, centrosome localization Golgi apparatus, centriole, cilium, dendrite terminus, intraflagellar transport particle B, microtubule basal body protein binding Human UniProtKB:Q9BQD3 IFT27 BHF-UCL UniProtKB {GO:0031514=GO_REF:0000024, GO:0007264=GO_REF:0000002, GO:0030992=GO_REF:0000024, GO:0005525=GO_REF:0000037} Q9BW83 Intraflagellar transport protein 27 homolog protein 20110314 {GO:0031514=ISS, GO:0007264=IEA, GO:0030992=ISS, GO:0005525=IEA} small GTPase mediated signal transduction intraflagellar transport particle B, motile cilium GTP binding Human UniProtKB:A8HN58 IFT43 UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0060271=PMID:21378380, GO:0030991=PMID:20889716, GO:0005856=GO_REF:0000039, GO:0035721=PMID:21378380} Q96FT9 Intraflagellar transport protein 43 homolog protein 20130222 {GO:0005737=IEA, GO:0060271=IMP, GO:0030991=IDA, GO:0005856=IEA, GO:0035721=IMP} cilium morphogenesis, intraflagellar retrograde transport cytoplasm, cytoskeleton, intraflagellar transport particle A Human IFT46 BHF-UCL UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0043234=GO_REF:0000019, GO:0005737=GO_REF:0000054, GO:0042073=GO_REF:0000024, GO:0031514=GO_REF:0000024, GO:0050821=GO_REF:0000024, GO:0009296=GO_REF:0000024, GO:0005634=PMID:10873569, GO:0005932=GO_REF:0000024, GO:0031512=GO_REF:0000019, GO:0008022=GO_REF:0000024} Q9NQC8 Intraflagellar transport protein 46 homolog protein 20110314 {GO:0008150=ND, GO:0003674=ND, GO:0043234=IEA, GO:0005737=IDA, GO:0042073=ISS, GO:0031514=ISS, GO:0050821=ISS, GO:0009296=ISS, GO:0005634=NAS, GO:0005932=ISS, GO:0031512=IEA, GO:0008022=ISS} biological_process, flagellum assembly, intraflagellar transport, protein stabilization cytoplasm, microtubule basal body, motile cilium, motile primary cilium, nucleus, protein complex molecular_function, protein C-terminus binding Human UniProtKB:A2T2X4 IFT52 BHF-UCL UniProtKB {GO:0001947=GO_REF:0000019, GO:0031514=GO_REF:0000024, GO:0030992=GO_REF:0000024, GO:0044292=GO_REF:0000019, GO:0032391=GO_REF:0000019, GO:0009953=GO_REF:0000019, GO:0008022=GO_REF:0000024, GO:0045862=GO_REF:0000019, GO:0042733=GO_REF:0000019, GO:0007224=GO_REF:0000019, GO:0001841=GO_REF:0000019} Q9Y366 Intraflagellar transport protein 52 homolog protein 20110314 {GO:0001947=IEA, GO:0031514=ISS, GO:0030992=ISS, GO:0044292=IEA, GO:0032391=IEA, GO:0009953=IEA, GO:0008022=ISS, GO:0045862=IEA, GO:0042733=IEA, GO:0007224=IEA, GO:0001841=IEA} dorsal/ventral pattern formation, embryonic digit morphogenesis, heart looping, neural tube formation, positive regulation of proteolysis, smoothened signaling pathway dendrite terminus, intraflagellar transport particle B, motile cilium, photoreceptor connecting cilium protein C-terminus binding Human UniProtKB:Q946G4 IFT57 IntAct UniProtKB {GO:0005515=PMID:18188704, GO:0006355=GO_REF:0000037, GO:0005794=GO_REF:0000019, GO:0006919=PMID:11788820, GO:0006915=PMID:11788820, GO:0044292=GO_REF:0000019, GO:0032391=GO_REF:0000019, GO:0042981=PMID:11788820, GO:0005932=GO_REF:0000024, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9NWB7 Intraflagellar transport protein 57 homolog protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0005794=IEA, GO:0006919=IDA, GO:0006915=IDA, GO:0044292=IEA, GO:0032391=IEA, GO:0042981=IDA, GO:0005932=ISS, GO:0003677=IEA, GO:0006351=IEA} activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, regulation of apoptotic process, regulation of transcription, DNA-dependent, transcription, DNA-dependent Golgi apparatus, dendrite terminus, microtubule basal body, photoreceptor connecting cilium DNA binding, protein binding Human UniProtKB:Q6QNY1 IFT74 HPA UniProtKB {GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0031514=GO_REF:0000024, GO:0045944=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0033630=GO_REF:0000019, GO:0030992=GO_REF:0000024, GO:0016023=GO_REF:0000039, GO:0005634=GO_REF:0000019} Q96LB3 Intraflagellar transport protein 74 homolog protein 20111111 {GO:0005813=IDA, GO:0005737=IDA, GO:0031514=ISS, GO:0045944=IEA, GO:0003682=IEA, GO:0033630=IEA, GO:0030992=ISS, GO:0016023=IEA, GO:0005634=IEA} positive regulation of cell adhesion mediated by integrin, positive regulation of transcription from RNA polymerase II promoter centrosome, cytoplasm, cytoplasmic membrane-bounded vesicle, intraflagellar transport particle B, motile cilium, nucleus chromatin binding Human IFT80 UniProtKB UniProtKB {GO:0005932=GO_REF:0000039, GO:0035085=GO_REF:0000039} Q9P2H3 Intraflagellar transport protein 80 homolog protein 20130413 {GO:0005932=IEA, GO:0035085=IEA} cilium axoneme, microtubule basal body Human UniProtKB-SubCell:SL-0304 IFT81 BHF-UCL UniProtKB {GO:0005813=GO_REF:0000019, GO:0031514=GO_REF:0000024, GO:0030992=GO_REF:0000024, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000024, GO:0030154=GO_REF:0000037} Q8WYA0 Intraflagellar transport protein 81 homolog protein 20110314 {GO:0005813=IEA, GO:0031514=ISS, GO:0030992=ISS, GO:0007275=IEA, GO:0007283=ISS, GO:0030154=IEA} cell differentiation, multicellular organismal development, spermatogenesis centrosome, intraflagellar transport particle B, motile cilium Human UniProtKB:Q68RJ5 IFT88 BHF-UCL UniProtKB {GO:0060426=GO_REF:0000019, GO:0007368=GO_REF:0000019, GO:0009953=GO_REF:0000019, GO:0035085=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0021537=GO_REF:0000019, GO:0007224=GO_REF:0000019, GO:0016485=GO_REF:0000019, GO:0048568=GO_REF:0000019, GO:0005932=GO_REF:0000024, GO:0003382=GO_REF:0000019, GO:0005814=GO_REF:0000024, GO:0031514=GO_REF:0000024, GO:0060411=GO_REF:0000019, GO:0045177=GO_REF:0000019, GO:0031512=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0045862=GO_REF:0000019, GO:0048853=GO_REF:0000019, GO:0005929=GO_REF:0000024, GO:0060271=GO_REF:0000024, GO:0032391=GO_REF:0000019, GO:0030992=GO_REF:0000024, GO:0042487=GO_REF:0000019, GO:0042733=GO_REF:0000019} Q13099 Intraflagellar transport protein 88 homolog protein 20110314 {GO:0060426=IEA, GO:0007368=IEA, GO:0009953=IEA, GO:0035085=IEA, GO:0009952=IEA, GO:0021537=IEA, GO:0007224=IEA, GO:0016485=IEA, GO:0048568=IEA, GO:0005932=ISS, GO:0003382=IEA, GO:0005814=ISS, GO:0031514=ISS, GO:0060411=IEA, GO:0045177=IEA, GO:0031512=IEA, GO:0001701=IEA, GO:0045862=IEA, GO:0048853=IEA, GO:0005929=ISS, GO:0060271=ISS, GO:0032391=IEA, GO:0030992=ISS, GO:0042487=IEA, GO:0042733=IEA} anterior/posterior pattern specification, cardiac septum morphogenesis, cilium morphogenesis, determination of left/right symmetry, dorsal/ventral pattern formation, embryonic digit morphogenesis, embryonic organ development, epithelial cell morphogenesis, forebrain morphogenesis, in utero embryonic development, lung vasculature development, positive regulation of proteolysis, protein processing, regulation of odontogenesis of dentin-containing tooth, smoothened signaling pathway, telencephalon development apical part of cell, centriole, cilium, cilium axoneme, intraflagellar transport particle B, microtubule basal body, motile cilium, motile primary cilium, photoreceptor connecting cilium Human UniProtKB:Q9FPW0 IGBP1 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0043066=GO_REF:0000019, GO:0035306=GO_REF:0000019, GO:0008601=PMID:9647778, GO:0035308=GO_REF:0000019, GO:0031434=GO_REF:0000019, GO:0000122=PMID:17438131, GO:0032873=PMID:17438131, GO:0042113=GO_REF:0000037, GO:0007165=PMID:9647778, GO:0060632=PMID:18949047, GO:0005737=PMID:9647778, GO:0045944=GO_REF:0000019, GO:0034612=PMID:17438131, GO:0043154=PMID:17438131, GO:0070555=PMID:17438131} P78318 Immunoglobulin-binding protein 1 protein 20130415 {GO:0005515=IPI, GO:0043066=IEA, GO:0035306=IEA, GO:0008601=IDA, GO:0035308=IEA, GO:0031434=IEA, GO:0000122=IMP, GO:0032873=IMP, GO:0042113=IEA, GO:0007165=NAS, GO:0060632=IMP, GO:0005737=NAS, GO:0045944=IEA, GO:0034612=IMP, GO:0043154=IMP, GO:0070555=IMP} B cell activation, negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of protein dephosphorylation, negative regulation of stress-activated MAPK cascade, negative regulation of transcription from RNA polymerase II promoter, positive regulation of dephosphorylation, positive regulation of transcription from RNA polymerase II promoter, regulation of microtubule-based movement, response to interleukin-1, response to tumor necrosis factor, signal transduction cytoplasm mitogen-activated protein kinase kinase binding, protein binding, protein phosphatase type 2A regulator activity Human UniProtKB:P67775 IGDCC3 ENSEMBL UniProtKB {GO:0005887=GO_REF:0000019, GO:0050885=GO_REF:0000019} Q8IVU1 Immunoglobulin superfamily DCC subclass member 3 protein 20130413 {GO:0005887=IEA, GO:0050885=IEA} neuromuscular process controlling balance integral to plasma membrane Human Ensembl:ENSMUSP00000034961 IGDCC4 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q8TDY8 Immunoglobulin superfamily DCC subclass member 4 protein 20130413 {GO:0005886=IEA, GO:0016021=IEA} integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 IGF1 BHF-UCL UniProtKB {GO:0005515=PMID:10766744, GO:0033160=PMID:19654000, GO:0005159=PMID:8452530, GO:0005158=PMID:8452530, GO:0050731=PMID:7782332, GO:0046579=PMID:9722506, GO:0030879=GO_REF:0000019, GO:0005615=PMID:7188854, GO:0060509=GO_REF:0000019, GO:0030104=GO_REF:0000019, GO:0046326=PMID:21076856, GO:0045445=PMID:17531227, GO:0070373=GO_REF:0000019, GO:0014834=PMID:17531227, GO:0045821=PMID:7688386, GO:2000288=GO_REF:0000019, GO:0050679=PMID:7188854, GO:0048839=GO_REF:0000019, GO:0048286=GO_REF:0000019, GO:0045740=GO_REF:0000024, GO:0030168=Reactome:REACT_798, GO:0060766=GO_REF:0000019, GO:0014068=PMID:7688386, GO:0045840=PMID:7188854, GO:0014904=PMID:17531227, GO:0070886=PMID:19654000, GO:0030166=PMID:12746903, GO:0001501=PMID:10448861, GO:0005178=PMID:19578119, GO:0007517=PMID:10448861, GO:0005179=PMID:7188854, GO:0043388=PMID:19654000, GO:0010001=GO_REF:0000019, GO:0051450=PMID:17531227, GO:0045893=PMID:9722506, GO:0035630=PMID:16433617, GO:0044267=Reactome:REACT_17015, GO:0008083=GO_REF:0000037, GO:0060426=GO_REF:0000019, GO:0051897=GO_REF:0000019, GO:0008284=PMID:12746903, GO:0060736=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0005886=Reactome:REACT_150464, GO:0032878=GO_REF:0000019, GO:0042523=PMID:9722506, GO:0021940=GO_REF:0000019, GO:0006928=PMID:10766744, GO:0007265=PMID:10848592, GO:0048146=PMID:7188854, GO:0014911=PMID:10766744, GO:0042104=PMID:15694994, GO:0035264=GO_REF:0000019, GO:0090201=GO_REF:0000024, GO:0014896=PMID:10191278, GO:0045944=PMID:16433617, GO:0040014=PMID:8421089, GO:0031093=Reactome:REACT_21351, GO:0010613=PMID:19654000, GO:0060527=GO_REF:0000019, GO:0043066=PMID:16942485, GO:0050650=GO_REF:0000019, GO:0045725=PMID:21076856, GO:0048015=PMID:7692086, GO:0060741=GO_REF:0000019, GO:0005576=Reactome:REACT_150464, GO:0048661=PMID:10766744, GO:0016942=PMID:10766744, GO:0045669=PMID:16433617, GO:0006260=PMID:10766744, GO:0007165=PMID:10448861, GO:0034392=PMID:16942485, GO:0009441=PMID:10448861, GO:0043568=PMID:10766744, GO:0001974=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0031017=GO_REF:0000019, GO:0002576=Reactome:REACT_318, GO:0060463=GO_REF:0000019, GO:0048009=GO_REF:0000019, GO:0060510=GO_REF:0000019, GO:0048754=GO_REF:0000019, GO:0043410=PMID:19654000} P05019 Insulin-like growth factor I protein 20110120 {GO:0005515=IPI, GO:0033160=IDA, GO:0005159=IPI, GO:0005158=IPI, GO:0050731=IDA, GO:0046579=IDA, GO:0030879=IEA, GO:0005615=IDA, GO:0060509=IEA, GO:0030104=IEA, GO:0046326=IDA, GO:0045445=IDA, GO:0070373=IEA, GO:0014834=IDA, GO:0045821=IDA, GO:2000288=IEA, GO:0050679=IDA, GO:0048839=IEA, GO:0048286=IEA, GO:0045740=ISS, GO:0030168=TAS, GO:0060766=IEA, GO:0014068=IDA, GO:0045840=IDA, GO:0014904=IDA, GO:0070886=IDA, GO:0030166=IDA, GO:0001501=TAS, GO:0005178=IDA, GO:0007517=TAS, GO:0005179=IDA, GO:0043388=IDA, GO:0010001=IEA, GO:0051450=IDA, GO:0045893=IDA, GO:0035630=IDA, GO:0044267=TAS, GO:0008083=IEA, GO:0060426=IEA, GO:0051897=IEA, GO:0008284=IDA, GO:0060736=IEA, GO:0008285=IEA, GO:0005886=TAS, GO:0032878=IEA, GO:0042523=IDA, GO:0021940=IEA, GO:0006928=TAS, GO:0007265=TAS, GO:0048146=IDA, GO:0014911=IDA, GO:0042104=IDA, GO:0035264=IEA, GO:0090201=ISS, GO:0014896=IMP, GO:0045944=IDA, GO:0040014=IEP, GO:0031093=TAS, GO:0010613=IDA, GO:0060527=IEA, GO:0043066=IDA, GO:0050650=IEA, GO:0045725=IDA, GO:0048015=IDA, GO:0060741=IEA, GO:0005576=TAS, GO:0048661=IDA, GO:0016942=IC, GO:0045669=IDA, GO:0006260=TAS, GO:0007165=TAS, GO:0034392=IDA, GO:0009441=TAS, GO:0043568=IDA, GO:0001974=IEA, GO:0007596=TAS, GO:0031017=IEA, GO:0002576=TAS, GO:0060463=IEA, GO:0048009=IEA, GO:0060510=IEA, GO:0048754=IEA, GO:0043410=IDA} DNA replication, Ras protein signal transduction, Type I pneumocyte differentiation, Type II pneumocyte differentiation, blood coagulation, blood vessel remodeling, bone mineralization involved in bone maturation, branching morphogenesis of an epithelial tube, cellular component movement, cellular protein metabolic process, chondroitin sulfate proteoglycan biosynthetic process, exocrine pancreas development, glial cell differentiation, glycolate metabolic process, inner ear development, insulin-like growth factor receptor signaling pathway, lung alveolus development, lung lobe morphogenesis, lung vasculature development, mammary gland development, multicellular organism growth, muscle hypertrophy, muscle organ development, myoblast differentiation, myoblast proliferation, myotube cell development, negative regulation of ERK1 and ERK2 cascade, negative regulation of androgen receptor signaling pathway, negative regulation of apoptotic process, negative regulation of cell proliferation, negative regulation of release of cytochrome c from mitochondria, negative regulation of smooth muscle cell apoptotic process, phosphatidylinositol-mediated signaling, platelet activation, platelet degranulation, positive regulation of DNA binding, positive regulation of DNA replication, positive regulation of MAPK cascade, positive regulation of Ras protein signal transduction, positive regulation of activated T cell proliferation, positive regulation of calcineurin-NFAT signaling cascade, positive regulation of cardiac muscle hypertrophy, positive regulation of cell proliferation, positive regulation of cerebellar granule cell precursor proliferation, positive regulation of epithelial cell proliferation, positive regulation of fibroblast proliferation, positive regulation of glucose import, positive regulation of glycogen biosynthetic process, positive regulation of glycolysis, positive regulation of insulin-like growth factor receptor signaling pathway, positive regulation of mitosis, positive regulation of myoblast proliferation, positive regulation of osteoblast differentiation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of protein import into nucleus, translocation, positive regulation of protein kinase B signaling cascade, positive regulation of smooth muscle cell migration, positive regulation of smooth muscle cell proliferation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of tyrosine phosphorylation of Stat5 protein, prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis, prostate gland growth, prostate gland stromal morphogenesis, proteoglycan biosynthetic process, regulation of establishment or maintenance of cell polarity, regulation of multicellular organism growth, satellite cell maintenance involved in skeletal muscle regeneration, signal transduction, skeletal system development, water homeostasis extracellular region, extracellular space, insulin-like growth factor binding protein complex, plasma membrane, platelet alpha granule lumen growth factor activity, hormone activity, insulin receptor binding, insulin-like growth factor receptor binding, integrin binding, protein binding Human IGF1R BHF-UCL UniProtKB {GO:0005515=PMID:21685939, GO:0005158=PMID:8452530, GO:0030879=GO_REF:0000019, GO:0043560=PMID:7541045, GO:0030010=GO_REF:0000019, GO:0007409=GO_REF:0000019, GO:0042802=PMID:11448933, GO:0043231=PMID:8452530, GO:0046328=PMID:12556535, GO:0046777=PMID:11162456, GO:0033197=GO_REF:0000019, GO:0043559=PMID:8452530, GO:0005520=PMID:1846292, GO:0030335=PMID:12138094, GO:0032467=GO_REF:0000019, GO:0045740=PMID:12138094, GO:0051389=PMID:12556535, GO:0014065=PMID:7541045, GO:0007420=GO_REF:0000019, GO:0005887=PMID:7679099, GO:0043548=PMID:7541045, GO:0051898=GO_REF:0000019, GO:0008286=PMID:10829031, GO:0051897=GO_REF:0000019, GO:0043005=GO_REF:0000019, GO:0008284=PMID:10749889, GO:0005886=Reactome:REACT_150464, GO:0031994=PMID:8452530, GO:0051291=GO_REF:0000019, GO:0043409=GO_REF:0000019, GO:0001965=GO_REF:0000019, GO:0006955=PMID:16886151, GO:0030238=GO_REF:0000019, GO:0090031=GO_REF:0000019, GO:0043066=PMID:12556535, GO:0051054=GO_REF:0000019, GO:0051262=PMID:1846292, GO:0048015=PMID:7692086, GO:0060740=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0007165=PMID:3003744, GO:0016020=PMID:8452530, GO:0005901=GO_REF:0000019, GO:0031017=GO_REF:0000019, GO:0005010=PMID:7679099, GO:0006468=GO_REF:0000019, GO:0048009=PMID:7679099, GO:0016021=GO_REF:0000038, GO:0004713=Reactome:REACT_150288, GO:0043410=GO_REF:0000019, GO:0004714=GO_REF:0000002, GO:0007169=GO_REF:0000002} P08069 Insulin-like growth factor 1 receptor protein 20080528 {GO:0005515=IPI, GO:0005158=IDA, GO:0030879=IEA, GO:0043560=IPI, GO:0030010=IEA, GO:0007409=IEA, GO:0042802=IPI, GO:0043231=IDA, GO:0046328=IDA, GO:0046777=IDA, GO:0033197=IEA, GO:0043559=IPI, GO:0005520=IDA, GO:0030335=IMP, GO:0032467=IEA, GO:0045740=IMP, GO:0051389=IDA, GO:0014065=IC, GO:0007420=IEA, GO:0005887=IC, GO:0043548=IPI, GO:0051898=IEA, GO:0008286=TAS, GO:0051897=IEA, GO:0043005=IEA, GO:0008284=TAS, GO:0005886=TAS, GO:0031994=IPI, GO:0051291=IEA, GO:0043409=IEA, GO:0001965=IEA, GO:0006955=IMP, GO:0030238=IEA, GO:0090031=IEA, GO:0043066=IDA, GO:0051054=IEA, GO:0051262=IDA, GO:0048015=IDA, GO:0060740=IEA, GO:0005524=IEA, GO:0007165=TAS, GO:0016020=IDA, GO:0005901=IEA, GO:0031017=IEA, GO:0005010=IDA, GO:0006468=IEA, GO:0048009=IDA, GO:0016021=IEA, GO:0004713=TAS, GO:0043410=IEA, GO:0004714=IEA, GO:0007169=IEA} axonogenesis, brain development, establishment of cell polarity, exocrine pancreas development, immune response, inactivation of MAPKK activity, insulin receptor signaling pathway, insulin-like growth factor receptor signaling pathway, male sex determination, mammary gland development, negative regulation of MAPK cascade, negative regulation of apoptotic process, negative regulation of protein kinase B signaling cascade, phosphatidylinositol 3-kinase cascade, phosphatidylinositol-mediated signaling, positive regulation of DNA metabolic process, positive regulation of DNA replication, positive regulation of MAPK cascade, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of cytokinesis, positive regulation of protein kinase B signaling cascade, positive regulation of steroid hormone biosynthetic process, prostate gland epithelium morphogenesis, protein autophosphorylation, protein heterooligomerization, protein phosphorylation, protein tetramerization, regulation of JNK cascade, response to vitamin E, signal transduction, transmembrane receptor protein tyrosine kinase signaling pathway caveola, integral to membrane, integral to plasma membrane, intracellular membrane-bounded organelle, membrane, neuron projection, plasma membrane ATP binding, G-protein alpha-subunit binding, identical protein binding, insulin binding, insulin receptor binding, insulin receptor substrate binding, insulin-like growth factor I binding, insulin-like growth factor binding, insulin-like growth factor-activated receptor activity, phosphatidylinositol 3-kinase binding, protein binding, protein tyrosine kinase activity, transmembrane receptor protein tyrosine kinase activity Human UniProtKB:P01308 IGF2 GOC UniProtKB {GO:0008286=PMID:1845984, GO:0005515=PMID:10611375, GO:0051897=PMID:11500939, GO:0008284=PMID:11500939, GO:0071902=GO_REF:0000024, GO:0005886=Reactome:REACT_150464, GO:0005159=PMID:1845984, GO:0005158=PMID:12138094, GO:0050731=GO_REF:0000024, GO:2000273=GO_REF:0000024, GO:0005615=GO_REF:0000002, GO:0042104=PMID:15694994, GO:0006006=GO_REF:0000037, GO:0051781=GO_REF:0000037, GO:0031093=Reactome:REACT_21351, GO:2000467=GO_REF:0000024, GO:0006355=PMID:12881524, GO:0045725=GO_REF:0000024, GO:0030168=Reactome:REACT_798, GO:0046628=PMID:11500939, GO:0007275=PMID:6382022, GO:0005576=Reactome:REACT_150464, GO:0045840=PMID:11500939, GO:0038028=GO_REF:0000024, GO:0043085=GO_REF:0000024, GO:0001501=PMID:8298652, GO:0005179=GO_REF:0000037, GO:0001503=GO_REF:0000037, GO:0007596=Reactome:REACT_604, GO:0030546=GO_REF:0000024, GO:0002576=Reactome:REACT_318, GO:0001934=GO_REF:0000024, GO:0006349=PMID:8968759, GO:0043539=GO_REF:0000024, GO:0043410=PMID:11500939, GO:0044267=Reactome:REACT_17015, GO:0008083=PMID:11500939} P01344 Insulin-like growth factor II protein 20130413 {GO:0008286=TAS, GO:0005515=IPI, GO:0051897=IDA, GO:0008284=IC, GO:0071902=ISS, GO:0005886=TAS, GO:0005159=TAS, GO:0005158=IPI, GO:0050731=ISS, GO:2000273=ISS, GO:0005615=IEA, GO:0042104=IDA, GO:0006006=IEA, GO:0051781=IEA, GO:0031093=TAS, GO:2000467=ISS, GO:0006355=NAS, GO:0045725=ISS, GO:0030168=TAS, GO:0046628=IDA, GO:0007275=TAS, GO:0005576=TAS, GO:0045840=IDA, GO:0038028=ISS, GO:0043085=ISS, GO:0001501=TAS, GO:0005179=IEA, GO:0001503=IEA, GO:0007596=TAS, GO:0030546=ISS, GO:0002576=TAS, GO:0001934=ISS, GO:0006349=TAS, GO:0043539=ISS, GO:0043410=IDA, GO:0044267=TAS, GO:0008083=IDA} blood coagulation, cellular protein metabolic process, glucose metabolic process, insulin receptor signaling pathway, insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade, multicellular organismal development, ossification, platelet activation, platelet degranulation, positive regulation of MAPK cascade, positive regulation of activated T cell proliferation, positive regulation of catalytic activity, positive regulation of cell division, positive regulation of cell proliferation, positive regulation of glycogen (starch) synthase activity, positive regulation of glycogen biosynthetic process, positive regulation of insulin receptor signaling pathway, positive regulation of mitosis, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of protein kinase B signaling cascade, positive regulation of protein phosphorylation, positive regulation of protein serine/threonine kinase activity, positive regulation of receptor activity, regulation of gene expression by genetic imprinting, regulation of transcription, DNA-dependent, skeletal system development extracellular region, extracellular space, plasma membrane, platelet alpha granule lumen growth factor activity, hormone activity, insulin receptor binding, insulin-like growth factor receptor binding, protein binding, protein serine/threonine kinase activator activity, receptor activator activity Human UniProtKB:P09535 IGF2BP1 HPA UniProtKB {GO:0017148=PMID:9891060, GO:0005515=PMID:17932509, GO:0048027=PMID:9891060, GO:0010467=Reactome:REACT_71, GO:0070934=PMID:19029303, GO:0005886=GO_REF:0000052, GO:0010494=PMID:17101699, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003729=PMID:17289661, GO:0045182=PMID:9891060, GO:0006403=GO_REF:0000019, GO:0030027=GO_REF:0000039, GO:0043231=GO_REF:0000052, GO:0005829=Reactome:REACT_22241, GO:0042035=PMID:9891060, GO:0005737=GO_REF:0000052, GO:0000166=GO_REF:0000002, GO:0043197=GO_REF:0000039, GO:0030529=PMID:17289661, GO:0003730=PMID:20080952, GO:0010610=PMID:17101699, GO:0070937=PMID:19029303} Q9NZI8 Insulin-like growth factor 2 mRNA-binding protein 1 protein 20101115 {GO:0017148=IDA, GO:0005515=IPI, GO:0048027=IDA, GO:0010467=TAS, GO:0070934=IDA, GO:0005886=IDA, GO:0010494=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0003729=IDA, GO:0045182=IDA, GO:0006403=IEA, GO:0030027=IEA, GO:0043231=IDA, GO:0005829=TAS, GO:0042035=IC, GO:0005737=IDA, GO:0000166=IEA, GO:0043197=IEA, GO:0030529=IDA, GO:0003730=IDA, GO:0010610=IMP, GO:0070937=IDA} CRD-mediated mRNA stabilization, RNA localization, gene expression, negative regulation of translation, regulation of cytokine biosynthetic process, regulation of mRNA stability involved in response to stress CRD-mediated mRNA stability complex, cytoplasm, cytoplasmic stress granule, cytosol, dendritic spine, intracellular membrane-bounded organelle, lamellipodium, nucleolus, nucleus, plasma membrane, ribonucleoprotein complex mRNA 3'-UTR binding, mRNA 5'-UTR binding, mRNA binding, nucleotide binding, protein binding, translation regulator activity Human IGF2BP2 BHF-UCL UniProtKB {GO:0005515=PMID:12674497, GO:0017148=PMID:9891060, GO:0010467=Reactome:REACT_71, GO:0048027=PMID:9891060, GO:0003723=GO_REF:0000002, GO:0005634=PMID:15618018, GO:0009653=PMID:9891060, GO:0045182=PMID:9891060, GO:0005829=Reactome:REACT_22195, GO:0042035=PMID:9891060, GO:0005737=PMID:15618018, GO:0000166=GO_REF:0000002, GO:0003730=PMID:20080952, GO:0005856=PMID:15618018} Q9Y6M1 Insulin-like growth factor 2 mRNA-binding protein 2 protein 20080328 {GO:0005515=IPI, GO:0017148=ISS, GO:0010467=TAS, GO:0048027=IDA, GO:0003723=IEA, GO:0005634=IDA, GO:0009653=TAS, GO:0045182=ISS, GO:0005829=TAS, GO:0042035=IC, GO:0005737=IDA, GO:0000166=IEA, GO:0003730=IDA, GO:0005856=IDA} anatomical structure morphogenesis, gene expression, negative regulation of translation, regulation of cytokine biosynthetic process cytoplasm, cytoskeleton, cytosol, nucleus RNA binding, mRNA 3'-UTR binding, mRNA 5'-UTR binding, nucleotide binding, protein binding, translation regulator activity Human GO:0048027 IGF2BP3 HPA UniProtKB {GO:0005515=PMID:17289661, GO:0017148=PMID:9891060, GO:0048027=PMID:9891060, GO:0010467=Reactome:REACT_71, GO:0003723=PMID:9891060, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002, GO:0006412=PMID:9891060, GO:0009653=PMID:9891060, GO:0045182=PMID:9891060, GO:0005829=Reactome:REACT_22429, GO:0042035=PMID:9891060, GO:0005737=GO_REF:0000052, GO:0000166=GO_REF:0000002, GO:0003730=PMID:20080952} O00425 Insulin-like growth factor 2 mRNA-binding protein 3 protein 20080818 {GO:0005515=IPI, GO:0017148=ISS, GO:0048027=IDA, GO:0010467=TAS, GO:0003723=TAS, GO:0005634=IEA, GO:0003676=IEA, GO:0006412=TAS, GO:0009653=TAS, GO:0045182=ISS, GO:0005829=TAS, GO:0042035=IC, GO:0005737=IDA, GO:0000166=IEA, GO:0003730=IDA} anatomical structure morphogenesis, gene expression, negative regulation of translation, regulation of cytokine biosynthetic process, translation cytoplasm, cytosol, nucleus RNA binding, mRNA 3'-UTR binding, mRNA 5'-UTR binding, nucleic acid binding, nucleotide binding, protein binding, translation regulator activity Human IGF2R GOC UniProtKB {GO:0051219=PMID:10900005, GO:0005515=PMID:10900005, GO:0005215=GO_REF:0000002, GO:0009986=PMID:10900005, GO:0030139=PMID:10900005, GO:0005765=GO_REF:0000039, GO:0005537=GO_REF:0000019, GO:0006898=PMID:10799489, GO:0007165=PMID:7753549, GO:0001948=PMID:10900005, GO:0005887=PMID:10799489, GO:0005641=GO_REF:0000019, GO:0005010=PMID:10799489, GO:0048009=PMID:10799489, GO:0004872=PMID:7753549, GO:0030140=PMID:15078902, GO:0005768=PMID:15078902, GO:0005520=GO_REF:0000019} P11717 Cation-independent mannose-6-phosphate receptor protein 20130413 {GO:0051219=IDA, GO:0005515=IPI, GO:0005215=IEA, GO:0009986=IDA, GO:0030139=IDA, GO:0005765=IEA, GO:0005537=IEA, GO:0006898=TAS, GO:0007165=TAS, GO:0001948=IDA, GO:0005887=TAS, GO:0005641=IEA, GO:0005010=TAS, GO:0048009=TAS, GO:0004872=TAS, GO:0030140=IDA, GO:0005768=IDA, GO:0005520=IEA} insulin-like growth factor receptor signaling pathway, receptor-mediated endocytosis, signal transduction cell surface, endocytic vesicle, endosome, integral to plasma membrane, lysosomal membrane, nuclear envelope lumen, trans-Golgi network transport vesicle glycoprotein binding, insulin-like growth factor binding, insulin-like growth factor-activated receptor activity, mannose binding, phosphoprotein binding, protein binding, receptor activity, transporter activity Human IGFALS HPA UniProtKB {GO:0007165=PMID:1384485, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005576=Reactome:REACT_15475, GO:0007155=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0005615=GO_REF:0000039, GO:0005520=PMID:1379671} P35858 Insulin-like growth factor-binding protein complex acid labile subunit protein 20111111 {GO:0007165=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0005576=TAS, GO:0007155=IEA, GO:0044267=TAS, GO:0005615=IEA, GO:0005520=TAS} cell adhesion, cellular protein metabolic process, signal transduction extracellular region, extracellular space, nucleolus, nucleus insulin-like growth factor binding NOT Human IGFBP1 Reactome UniProtKB {GO:0008286=GO_REF:0000019, GO:0007165=PMID:2454104, GO:0030307=GO_REF:0000019, GO:0005576=Reactome:REACT_115690, GO:0006987=Reactome:REACT_18277, GO:0042246=GO_REF:0000019, GO:0044267=Reactome:REACT_17015, GO:0005615=GO_REF:0000019, GO:0001558=GO_REF:0000002, GO:0030968=Reactome:REACT_18356, GO:0005520=GO_REF:0000019} P08833 Insulin-like growth factor-binding protein 1 protein 20111021 {GO:0008286=IEA, GO:0007165=TAS, GO:0030307=IEA, GO:0005576=TAS, GO:0006987=TAS, GO:0042246=IEA, GO:0044267=TAS, GO:0005615=IEA, GO:0001558=IEA, GO:0030968=TAS, GO:0005520=IEA} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, insulin receptor signaling pathway, positive regulation of cell growth, regulation of cell growth, signal transduction, tissue regeneration extracellular region, extracellular space insulin-like growth factor binding Human IGFBP2 BHF-UCL UniProtKB {GO:0007565=GO_REF:0000019, GO:0007584=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0006950=GO_REF:0000019, GO:0031994=PMID:19081843, GO:0031995=GO_REF:0000024, GO:0051384=GO_REF:0000019, GO:0005576=Reactome:REACT_15419, GO:0031410=GO_REF:0000019, GO:0001558=GO_REF:0000002, GO:0005615=PMID:15694994, GO:0032870=GO_REF:0000019, GO:0009612=GO_REF:0000019, GO:0042104=PMID:15694994, GO:0007165=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0010226=GO_REF:0000019, GO:0043567=GO_REF:0000024, GO:0032526=GO_REF:0000019, GO:0044267=Reactome:REACT_17015, GO:0032355=GO_REF:0000019, GO:0005520=GO_REF:0000002} P18065 Insulin-like growth factor-binding protein 2 protein 20110421 {GO:0007565=IEA, GO:0007584=IEA, GO:0042493=IEA, GO:0007568=IEA, GO:0006950=IEA, GO:0031994=IDA, GO:0031995=ISS, GO:0051384=IEA, GO:0005576=TAS, GO:0031410=IEA, GO:0001558=IEA, GO:0005615=IDA, GO:0032870=IEA, GO:0009612=IEA, GO:0042104=IDA, GO:0007165=IEA, GO:0016324=IEA, GO:0010226=IEA, GO:0043567=ISS, GO:0032526=IEA, GO:0044267=TAS, GO:0032355=IEA, GO:0005520=IEA} aging, cellular protein metabolic process, cellular response to hormone stimulus, female pregnancy, positive regulation of activated T cell proliferation, regulation of cell growth, regulation of insulin-like growth factor receptor signaling pathway, response to drug, response to estradiol stimulus, response to glucocorticoid stimulus, response to lithium ion, response to mechanical stimulus, response to nutrient, response to retinoic acid, response to stress, signal transduction apical plasma membrane, cytoplasmic vesicle, extracellular region, extracellular space insulin-like growth factor I binding, insulin-like growth factor II binding, insulin-like growth factor binding Human IGFBP3 BHF-UCL UniProtKB {GO:0005515=PMID:9388210, GO:0008285=PMID:19258508, GO:0031994=PMID:10766744, GO:0005634=PMID:17434920, GO:0001558=GO_REF:0000019, GO:0005615=PMID:17119061, GO:0046872=PMID:14576163, GO:0010906=GO_REF:0000019, GO:0014912=PMID:10766744, GO:0008160=PMID:11940579, GO:0044342=GO_REF:0000019, GO:0009968=PMID:11940579, GO:0001968=GO_REF:0000019, GO:0005520=PMID:12599210, GO:0043065=PMID:11971816, GO:0006915=GO_REF:0000037, GO:0005576=Reactome:REACT_15475, GO:0048662=PMID:10766744, GO:0016942=PMID:10766744, GO:0043568=GO_REF:0000019, GO:0045663=PMID:12599210, GO:0001933=PMID:17591901, GO:0006468=PMID:17434920, GO:0043410=GO_REF:0000019, GO:0044267=Reactome:REACT_17015} P17936 Insulin-like growth factor-binding protein 3 protein 20080530 {GO:0005515=IPI, GO:0008285=IGI, GO:0031994=IPI, GO:0005634=IDA, GO:0001558=IEA, GO:0005615=IDA, GO:0046872=NAS, GO:0010906=IEA, GO:0014912=IDA, GO:0008160=IDA, GO:0044342=IEA, GO:0009968=NAS, GO:0001968=IEA, GO:0005520=NAS, GO:0043065=IMP, GO:0006915=IEA, GO:0005576=TAS, GO:0048662=IDA, GO:0016942=IC, GO:0043568=IEA, GO:0045663=IDA, GO:0001933=IDA, GO:0006468=IDA, GO:0043410=IEA, GO:0044267=TAS} apoptotic process, cellular protein metabolic process, negative regulation of cell proliferation, negative regulation of protein phosphorylation, negative regulation of signal transduction, negative regulation of smooth muscle cell migration, negative regulation of smooth muscle cell proliferation, positive regulation of MAPK cascade, positive regulation of apoptotic process, positive regulation of insulin-like growth factor receptor signaling pathway, positive regulation of myoblast differentiation, protein phosphorylation, regulation of cell growth, regulation of glucose metabolic process, type B pancreatic cell proliferation extracellular region, extracellular space, insulin-like growth factor binding protein complex, nucleus fibronectin binding, insulin-like growth factor I binding, insulin-like growth factor binding, metal ion binding, protein binding, protein tyrosine phosphatase activator activity Human IGFBP4 Reactome UniProtKB {GO:0008283=PMID:1377672, GO:0005576=Reactome:REACT_15447, GO:0006259=PMID:1377672, GO:0001558=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0010906=GO_REF:0000019, GO:0007165=PMID:1377672, GO:0001501=PMID:1377672, GO:0006954=GO_REF:0000019, GO:0044342=GO_REF:0000019, GO:0043568=GO_REF:0000019, GO:0043410=GO_REF:0000019, GO:0044267=Reactome:REACT_17015, GO:0005520=GO_REF:0000019} P22692 Insulin-like growth factor-binding protein 4 protein 20081119 {GO:0008283=TAS, GO:0005576=TAS, GO:0006259=TAS, GO:0001558=IEA, GO:0005615=IEA, GO:0010906=IEA, GO:0007165=TAS, GO:0001501=TAS, GO:0006954=IEA, GO:0044342=IEA, GO:0043568=IEA, GO:0043410=IEA, GO:0044267=TAS, GO:0005520=IEA} DNA metabolic process, cell proliferation, cellular protein metabolic process, inflammatory response, positive regulation of MAPK cascade, positive regulation of insulin-like growth factor receptor signaling pathway, regulation of cell growth, regulation of glucose metabolic process, signal transduction, skeletal system development, type B pancreatic cell proliferation extracellular region, extracellular space insulin-like growth factor binding Human IGFBP5 BHF-UCL UniProtKB {GO:0048630=GO_REF:0000019, GO:0005515=PMID:15700281, GO:0017148=PMID:15700281, GO:0051897=GO_REF:0000019, GO:0031994=PMID:10766744, GO:0001558=GO_REF:0000019, GO:0014912=PMID:10766744, GO:0010906=GO_REF:0000019, GO:0031069=GO_REF:0000019, GO:0035556=GO_REF:0000019, GO:0044342=GO_REF:0000019, GO:0006006=GO_REF:0000019, GO:0001968=GO_REF:0000019, GO:0005520=GO_REF:0000002, GO:0030336=PMID:15700281, GO:0060056=GO_REF:0000019, GO:0048662=PMID:10766744, GO:0005576=Reactome:REACT_15355, GO:0042593=GO_REF:0000019, GO:0016942=PMID:10766744, GO:0001649=GO_REF:0000019, GO:0007165=PMID:7525452, GO:0071407=PMID:7559606, GO:0045668=GO_REF:0000019, GO:0043569=PMID:10766744, GO:0043568=GO_REF:0000019, GO:0071320=PMID:7559606, GO:0044267=Reactome:REACT_17015, GO:0051146=GO_REF:0000019} P24593 Insulin-like growth factor-binding protein 5 protein 20080530 {GO:0048630=IEA, GO:0005515=IPI, GO:0017148=IDA, GO:0051897=IEA, GO:0031994=IPI, GO:0001558=IEA, GO:0014912=IDA, GO:0010906=IEA, GO:0031069=IEA, GO:0035556=IEA, GO:0044342=IEA, GO:0006006=IEA, GO:0001968=IEA, GO:0005520=IEA, GO:0030336=IDA, GO:0060056=IEA, GO:0048662=IDA, GO:0005576=TAS, GO:0042593=IEA, GO:0016942=IC, GO:0001649=IEA, GO:0007165=NAS, GO:0071407=IDA, GO:0045668=IEA, GO:0043569=IDA, GO:0043568=IEA, GO:0071320=IDA, GO:0044267=TAS, GO:0051146=IEA} cellular protein metabolic process, cellular response to cAMP, cellular response to organic cyclic compound, glucose homeostasis, glucose metabolic process, hair follicle morphogenesis, intracellular signal transduction, mammary gland involution, negative regulation of cell migration, negative regulation of insulin-like growth factor receptor signaling pathway, negative regulation of osteoblast differentiation, negative regulation of smooth muscle cell migration, negative regulation of smooth muscle cell proliferation, negative regulation of translation, osteoblast differentiation, positive regulation of insulin-like growth factor receptor signaling pathway, positive regulation of protein kinase B signaling cascade, regulation of cell growth, regulation of glucose metabolic process, signal transduction, skeletal muscle tissue growth, striated muscle cell differentiation, type B pancreatic cell proliferation extracellular region, insulin-like growth factor binding protein complex fibronectin binding, insulin-like growth factor I binding, insulin-like growth factor binding, protein binding Human IGFBP6 Reactome UniProtKB {GO:0007165=PMID:10087296, GO:0008285=PMID:7539002, GO:0005794=GO_REF:0000019, GO:0031994=GO_REF:0000019, GO:0005576=Reactome:REACT_15506, GO:0044267=Reactome:REACT_17015, GO:0005615=GO_REF:0000019, GO:0001558=GO_REF:0000002, GO:0005520=GO_REF:0000002} P24592 Insulin-like growth factor-binding protein 6 protein 20081119 {GO:0007165=NAS, GO:0008285=TAS, GO:0005794=IEA, GO:0031994=IEA, GO:0005576=TAS, GO:0044267=TAS, GO:0005615=IEA, GO:0001558=IEA, GO:0005520=IEA} cellular protein metabolic process, negative regulation of cell proliferation, regulation of cell growth, signal transduction Golgi apparatus, extracellular region, extracellular space insulin-like growth factor I binding, insulin-like growth factor binding Human IGFBP7 PINC UniProtKB {GO:0005515=PMID:9388210, GO:0048839=GO_REF:0000019, GO:0008285=PMID:8939990, GO:0007155=PMID:8117260, GO:0001558=GO_REF:0000002, GO:0005520=GO_REF:0000002} Q16270 Insulin-like growth factor-binding protein 7 protein 20030904 {GO:0005515=IPI, GO:0048839=IEA, GO:0008285=TAS, GO:0007155=IDA, GO:0001558=IEA, GO:0005520=IEA} cell adhesion, inner ear development, negative regulation of cell proliferation, regulation of cell growth insulin-like growth factor binding, protein binding Human IGHMBP2 GOC UniProtKB {GO:0005515=PMID:19299493, GO:0008219=GO_REF:0000037, GO:0030424=GO_REF:0000024, GO:0003723=PMID:19158098, GO:0032575=PMID:19158098, GO:0005634=PMID:19299493, GO:0006412=PMID:19299493, GO:0008186=PMID:19158098, GO:0030426=GO_REF:0000024, GO:0005737=PMID:19299493, GO:0003697=PMID:8493094, GO:0051260=PMID:19299493, GO:0032508=PMID:8349627, GO:0008094=PMID:19158098, GO:0006355=GO_REF:0000037, GO:0043141=PMID:19158098, GO:0000049=PMID:19299493, GO:0006310=PMID:8349627, GO:0003677=PMID:19158098, GO:0005524=PMID:19158098, GO:0006351=GO_REF:0000037, GO:0003678=PMID:8349627, GO:0006260=PMID:8493094, GO:0006281=PMID:8493094, GO:0032797=PMID:19299493, GO:0030529=GO_REF:0000024, GO:0043022=PMID:19158098, GO:0008270=GO_REF:0000002, GO:0008134=PMID:19299493} P38935 DNA-binding protein SMUBP-2 protein 20130413 {GO:0005515=IPI, GO:0008219=IEA, GO:0030424=ISS, GO:0003723=IDA, GO:0032575=IDA, GO:0005634=IDA, GO:0006412=NAS, GO:0008186=IDA, GO:0030426=ISS, GO:0005737=IDA, GO:0003697=TAS, GO:0051260=IPI, GO:0032508=TAS, GO:0008094=IDA, GO:0006355=IEA, GO:0043141=IDA, GO:0000049=IDA, GO:0006310=TAS, GO:0003677=IDA, GO:0005524=IDA, GO:0006351=IEA, GO:0003678=TAS, GO:0006260=TAS, GO:0006281=TAS, GO:0032797=IDA, GO:0030529=ISS, GO:0043022=IDA, GO:0008270=IEA, GO:0008134=IPI} DNA duplex unwinding, DNA recombination, DNA repair, DNA replication, cell death, protein homooligomerization, regulation of transcription, DNA-dependent, transcription, DNA-dependent, translation SMN complex, axon, cytoplasm, growth cone, nucleus, ribonucleoprotein complex ATP binding, ATP-dependent 5'-3' DNA helicase activity, ATP-dependent 5'-3' RNA helicase activity, DNA binding, DNA helicase activity, DNA-dependent ATPase activity, RNA binding, RNA-dependent ATPase activity, protein binding, ribosome binding, single-stranded DNA binding, tRNA binding, transcription factor binding, zinc ion binding Human IGIP UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} A6NJ69 IgA-inducing protein homolog protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 IGJ UniProtKB UniProtKB {GO:0006955=PMID:2984306, GO:0005576=PMID:14718574, GO:0003823=PMID:2984306} P01591 Immunoglobulin J chain protein 20010921 {GO:0006955=NAS, GO:0005576=NAS, GO:0003823=NAS} immune response extracellular region antigen binding Human IGLL1 UniProtKB UniProtKB {GO:0006955=PMID:2501791, GO:0016020=PMID:2501791, GO:0005576=GO_REF:0000039} P15814 Immunoglobulin lambda-like polypeptide 1 protein 20010912 {GO:0006955=NAS, GO:0016020=NAS, GO:0005576=IEA} immune response extracellular region, membrane Human IGLL5 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} B9A064 Immunoglobulin lambda-like polypeptide 5 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 IGSF1 UniProtKB UniProtKB {GO:0005515=PMID:12421765, GO:0007165=PMID:11266516, GO:0006355=PMID:11266516, GO:0016020=PMID:11266516, GO:0034711=PMID:11266516, GO:0004872=PMID:11266516, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q8N6C5 Immunoglobulin superfamily member 1 protein 20100615 {GO:0005515=IPI, GO:0007165=IDA, GO:0006355=IDA, GO:0016020=IDA, GO:0034711=IDA, GO:0004872=IDA, GO:0005576=IEA, GO:0016021=IEA} regulation of transcription, DNA-dependent, signal transduction extracellular region, integral to membrane, membrane inhibin binding, protein binding, receptor activity Human UniProtKB:Q9ULT8 IGSF10 UniProtKB UniProtKB {GO:0001503=GO_REF:0000037, GO:0005576=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q6WRI0 Immunoglobulin superfamily member 10 protein 20130413 {GO:0001503=IEA, GO:0005576=IEA, GO:0007275=IEA, GO:0030154=IEA} cell differentiation, multicellular organismal development, ossification extracellular region Human UniProtKB-SubCell:SL-0243 IGSF11 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037, GO:0040008=GO_REF:0000037} Q5DX21 Immunoglobulin superfamily member 11 protein 20130413 {GO:0005886=IEA, GO:0016021=IEA, GO:0007155=IEA, GO:0040008=IEA} cell adhesion, regulation of growth integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 IGSF21 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q96ID5 Immunoglobulin superfamily member 21 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 IGSF22 null null {} null null null null {} null null null IGSF3 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} O75054 Immunoglobulin superfamily member 3 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 IGSF5 UniProtKB UniProtKB {GO:0016337=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0009986=GO_REF:0000019, GO:0005923=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0030165=GO_REF:0000019} Q9NSI5 Immunoglobulin superfamily member 5 protein 20130413 {GO:0016337=IEA, GO:0005886=IEA, GO:0009986=IEA, GO:0005923=IEA, GO:0016021=IEA, GO:0030165=IEA} cell-cell adhesion cell surface, integral to membrane, plasma membrane, tight junction PDZ domain binding Human UniProtKB-SubCell:SL-0265 IGSF6 PINC UniProtKB {GO:0006955=PMID:9809579, GO:0005887=PMID:9809579, GO:0007166=PMID:9809579, GO:0004888=PMID:9809579} O95976 Immunoglobulin superfamily member 6 protein 20030904 {GO:0006955=TAS, GO:0005887=TAS, GO:0007166=TAS, GO:0004888=TAS} cell surface receptor signaling pathway, immune response integral to plasma membrane transmembrane signaling receptor activity Human IGSF8 UniProtKB UniProtKB {GO:0007338=PMID:11504738, GO:0005515=PMID:11504738, GO:0005886=GO_REF:0000039, GO:0007519=PMID:11504738, GO:0008283=PMID:11504738, GO:0006928=PMID:11504738, GO:0016021=PMID:11504738, GO:0007399=PMID:11504738} Q969P0 Immunoglobulin superfamily member 8 protein 20090424 {GO:0007338=NAS, GO:0005515=IPI, GO:0005886=IEA, GO:0007519=NAS, GO:0008283=NAS, GO:0006928=NAS, GO:0016021=IDA, GO:0007399=NAS} cell proliferation, cellular component movement, nervous system development, single fertilization, skeletal muscle tissue development integral to membrane, plasma membrane protein binding Human UniProtKB:P60033 IGSF9 UniProtKB UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0045202=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0030425=GO_REF:0000019, GO:0016358=GO_REF:0000019} Q9P2J2 Protein turtle homolog A protein 20130413 {GO:0030054=IEA, GO:0005886=IEA, GO:0045202=IEA, GO:0016021=IEA, GO:0030425=IEA, GO:0016358=IEA} dendrite development cell junction, dendrite, integral to membrane, plasma membrane, synapse Human UniProtKB-SubCell:SL-0258 IHH BHF-UCL UniProtKB {GO:0033088=GO_REF:0000024, GO:0046638=GO_REF:0000024, GO:0033089=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0033085=GO_REF:0000024, GO:0051216=GO_REF:0000019, GO:0045453=GO_REF:0000019, GO:0060220=GO_REF:0000019, GO:0007267=GO_REF:0000029, GO:0005615=GO_REF:0000039, GO:0035988=GO_REF:0000019, GO:0005113=GO_REF:0000029, GO:0048596=GO_REF:0000019, GO:0046639=GO_REF:0000024, GO:0007224=GO_REF:0000019, GO:0001947=GO_REF:0000024, GO:0009880=GO_REF:0000019, GO:0045880=GO_REF:0000024, GO:0035264=GO_REF:0000019, GO:0015485=GO_REF:0000029, GO:0048666=GO_REF:0000019, GO:0048745=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0006508=GO_REF:0000037, GO:0048469=GO_REF:0000019, GO:0016539=GO_REF:0000002, GO:0003406=GO_REF:0000019, GO:0003382=GO_REF:0000019, GO:0090136=GO_REF:0000019, GO:0001569=GO_REF:0000019, GO:0072498=GO_REF:0000019, GO:0001708=GO_REF:0000019, GO:0005576=GO_REF:0000029, GO:0002053=GO_REF:0000019, GO:0006029=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0001649=GO_REF:0000019, GO:0031012=GO_REF:0000019, GO:0048074=GO_REF:0000019, GO:0030704=GO_REF:0000019, GO:0061053=GO_REF:0000024, GO:0032967=GO_REF:0000019, GO:0048557=GO_REF:0000019, GO:0031016=GO_REF:0000019, GO:0060323=GO_REF:0000019, GO:0008233=GO_REF:0000037, GO:0040008=GO_REF:0000019} Q14623 Indian hedgehog protein protein 20110719 {GO:0033088=ISS, GO:0046638=ISS, GO:0033089=ISS, GO:0005886=IEA, GO:0033085=ISS, GO:0051216=IEA, GO:0045453=IEA, GO:0060220=IEA, GO:0007267=NAS, GO:0005615=IEA, GO:0035988=IEA, GO:0005113=NAS, GO:0048596=IEA, GO:0046639=ISS, GO:0007224=IEA, GO:0001947=ISS, GO:0009880=IEA, GO:0045880=ISS, GO:0035264=IEA, GO:0015485=NAS, GO:0048666=IEA, GO:0048745=IEA, GO:0045944=IEA, GO:0006508=IEA, GO:0048469=IEA, GO:0016539=IEA, GO:0003406=IEA, GO:0003382=IEA, GO:0090136=IEA, GO:0001569=IEA, GO:0072498=IEA, GO:0001708=IEA, GO:0005576=NAS, GO:0002053=IEA, GO:0006029=IEA, GO:0001701=IEA, GO:0001649=IEA, GO:0031012=IEA, GO:0048074=IEA, GO:0030704=IEA, GO:0061053=ISS, GO:0032967=IEA, GO:0048557=IEA, GO:0031016=IEA, GO:0060323=IEA, GO:0008233=IEA, GO:0040008=IEA} bone resorption, camera-type eye photoreceptor cell fate commitment, cartilage development, cell fate specification, cell maturation, cell-cell signaling, chondrocyte proliferation, embryonic camera-type eye morphogenesis, embryonic digestive tract morphogenesis, embryonic pattern specification, embryonic skeletal joint development, epithelial cell morphogenesis, epithelial cell-cell adhesion, head morphogenesis, heart looping, in utero embryonic development, intein-mediated protein splicing, multicellular organism growth, negative regulation of T cell differentiation in thymus, negative regulation of alpha-beta T cell differentiation, negative regulation of eye pigmentation, negative regulation of immature T cell proliferation in thymus, neuron development, osteoblast differentiation, pancreas development, patterning of blood vessels, positive regulation of T cell differentiation in thymus, positive regulation of alpha-beta T cell differentiation, positive regulation of collagen biosynthetic process, positive regulation of mesenchymal cell proliferation, positive regulation of smoothened signaling pathway, positive regulation of transcription from RNA polymerase II promoter, proteoglycan metabolic process, proteolysis, regulation of growth, retinal pigment epithelium development, smooth muscle tissue development, smoothened signaling pathway, somite development, vitelline membrane formation extracellular matrix, extracellular region, extracellular space, plasma membrane cholesterol binding, patched binding, peptidase activity Human UniProtKB:P97812 IK IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0006955=PMID:7970704, GO:0007267=PMID:7970704, GO:0005634=GO_REF:0000039, GO:0005615=PMID:7970704} Q13123 Protein Red protein 20130415 {GO:0005515=IPI, GO:0006955=TAS, GO:0007267=TAS, GO:0005634=IEA, GO:0005615=TAS} cell-cell signaling, immune response extracellular space, nucleus protein binding Human UniProtKB:P04618 IKBIP HGNC UniProtKB {GO:0005515=PMID:15389287, GO:0010165=PMID:15389287, GO:0005783=PMID:15389287, GO:0005789=GO_REF:0000039, GO:0006917=PMID:15389287, GO:0016021=GO_REF:0000037} Q70UQ0 Inhibitor of nuclear factor kappa-B kinase-interacting protein protein 20060301 {GO:0005515=IPI, GO:0010165=IEP, GO:0005783=IDA, GO:0005789=IEA, GO:0006917=IMP, GO:0016021=IEA} induction of apoptosis, response to X-ray endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane protein binding Human IKBKAP GOC UniProtKB {GO:0005515=PMID:21903422, GO:0006368=PMID:11714725, GO:0030335=GO_REF:0000024, GO:0006357=PMID:11714725, GO:0005730=PMID:11714725, GO:0008023=PMID:11714725, GO:0003677=PMID:11714725, GO:0007165=PMID:9751059, GO:0005737=PMID:11714725, GO:0033588=PMID:22854966, GO:0006955=PMID:9751059, GO:0006461=PMID:9751059, GO:0016591=PMID:11714725, GO:0006468=PMID:9751059, GO:0008607=PMID:11818576, GO:0004871=PMID:9751059} O95163 Elongator complex protein 1 protein 20130413 {GO:0005515=IPI, GO:0006368=IDA, GO:0030335=ISS, GO:0006357=TAS, GO:0005730=IDA, GO:0008023=IDA, GO:0003677=IDA, GO:0007165=TAS, GO:0005737=IDA, GO:0033588=IDA, GO:0006955=TAS, GO:0006461=TAS, GO:0016591=IDA, GO:0006468=TAS, GO:0008607=IDA, GO:0004871=TAS} immune response, positive regulation of cell migration, protein complex assembly, protein phosphorylation, regulation of transcription from RNA polymerase II promoter, signal transduction, transcription elongation from RNA polymerase II promoter DNA-directed RNA polymerase II, holoenzyme, Elongator holoenzyme complex, cytoplasm, nucleolus, transcription elongation factor complex DNA binding, phosphorylase kinase regulator activity, protein binding, signal transducer activity Human IKBKB GOC UniProtKB {GO:0005515=PMID:22810585, GO:0035631=GO_REF:0000024, GO:0050852=Reactome:REACT_12526, GO:0034142=Reactome:REACT_6894, GO:0001782=GO_REF:0000019, GO:0008384=Reactome:REACT_22418, GO:0008385=PMID:18626576, GO:0070423=Reactome:REACT_75776, GO:0007249=PMID:18626576, GO:0005634=GO_REF:0000039, GO:2001259=GO_REF:0000019, GO:0035872=Reactome:REACT_75913, GO:0042802=PMID:21765415, GO:0005829=Reactome:REACT_118618, GO:0002756=Reactome:REACT_6809, GO:0005737=GO_REF:0000052, GO:0006954=PMID:18626576, GO:0051092=Reactome:REACT_21281, GO:0010765=GO_REF:0000019, GO:0002755=Reactome:REACT_27215, GO:0032481=Reactome:REACT_118823, GO:0043123=Reactome:REACT_24918, GO:0034138=Reactome:REACT_6783, GO:0048011=Reactome:REACT_13776, GO:0043066=Reactome:REACT_13537, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0019901=PMID:12492477, GO:0007252=Reactome:REACT_22418, GO:0034134=Reactome:REACT_7980, GO:0009615=PMID:18626576, GO:0002224=Reactome:REACT_9020, GO:0005524=GO_REF:0000037, GO:0004672=PMID:20434986, GO:0004674=Reactome:REACT_12399, GO:0045087=Reactome:REACT_6802, GO:0009898=GO_REF:0000024, GO:0035666=Reactome:REACT_25281, GO:0034166=Reactome:REACT_9027, GO:0006468=PMID:20434986, GO:0045121=GO_REF:0000039, GO:0034146=Reactome:REACT_9061, GO:0045893=PMID:9813230, GO:0034162=Reactome:REACT_9047} O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta protein 20130413 {GO:0005515=IPI, GO:0035631=ISS, GO:0050852=TAS, GO:0034142=TAS, GO:0001782=IEA, GO:0008384=TAS, GO:0008385=TAS, GO:0070423=TAS, GO:0007249=TAS, GO:0005634=IEA, GO:2001259=IEA, GO:0035872=TAS, GO:0042802=IPI, GO:0005829=TAS, GO:0002756=TAS, GO:0005737=IDA, GO:0006954=TAS, GO:0051092=TAS, GO:0010765=IEA, GO:0002755=TAS, GO:0032481=TAS, GO:0043123=TAS, GO:0034138=TAS, GO:0048011=TAS, GO:0043066=TAS, GO:0038124=TAS, GO:0038123=TAS, GO:0019901=IPI, GO:0007252=TAS, GO:0034134=TAS, GO:0009615=TAS, GO:0002224=TAS, GO:0005524=IEA, GO:0004672=IDA, GO:0004674=TAS, GO:0045087=TAS, GO:0009898=ISS, GO:0035666=TAS, GO:0034166=TAS, GO:0006468=IDA, GO:0045121=IEA, GO:0034146=TAS, GO:0045893=NAS, GO:0034162=TAS} B cell homeostasis, I-kappaB kinase/NF-kappaB cascade, I-kappaB phosphorylation, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, T cell receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, inflammatory response, innate immune response, negative regulation of apoptotic process, neurotrophin TRK receptor signaling pathway, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, nucleotide-binding oligomerization domain containing signaling pathway, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of cation channel activity, positive regulation of sodium ion transport, positive regulation of transcription, DNA-dependent, positive regulation of type I interferon production, protein phosphorylation, response to virus, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway CD40 receptor complex, IkappaB kinase complex, cytoplasm, cytosol, internal side of plasma membrane, membrane raft, nucleus ATP binding, IkappaB kinase activity, identical protein binding, protein binding, protein kinase activity, protein kinase binding, protein serine/threonine kinase activity Human IKBKE GOC UniProtKB {GO:0005515=PMID:21903422, GO:0034142=Reactome:REACT_6894, GO:0008384=GO_REF:0000003, GO:0008630=PMID:20188669, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0002224=Reactome:REACT_6966, GO:0005524=GO_REF:0000029, GO:0038061=PMID:10882136, GO:0005829=Reactome:REACT_25368, GO:0002756=Reactome:REACT_6809, GO:0006955=PMID:10421793, GO:0005737=GO_REF:0000052, GO:0004704=PMID:10882136, GO:0004672=Reactome:REACT_25368, GO:0045087=Reactome:REACT_6802, GO:0016605=PMID:20188669, GO:0035666=Reactome:REACT_25281, GO:0006468=PMID:20188669, GO:0043123=PMID:12761501, GO:0034138=Reactome:REACT_6783, GO:0032480=Reactome:REACT_25271, GO:0010008=Reactome:REACT_25081} Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon protein 20130413 {GO:0005515=IPI, GO:0034142=TAS, GO:0008384=IEA, GO:0008630=IMP, GO:0005730=IDA, GO:0005634=IDA, GO:0002224=TAS, GO:0005524=NAS, GO:0038061=IDA, GO:0005829=TAS, GO:0002756=TAS, GO:0006955=NAS, GO:0005737=IDA, GO:0004704=IDA, GO:0004672=TAS, GO:0045087=TAS, GO:0016605=IDA, GO:0035666=TAS, GO:0006468=IDA, GO:0043123=IEP, GO:0034138=TAS, GO:0032480=TAS, GO:0010008=TAS} MyD88-independent toll-like receptor signaling pathway, NIK/NF-kappaB cascade, TRIF-dependent toll-like receptor signaling pathway, immune response, innate immune response, intrinsic apoptotic signaling pathway in response to DNA damage, negative regulation of type I interferon production, positive regulation of I-kappaB kinase/NF-kappaB cascade, protein phosphorylation, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor signaling pathway PML body, cytoplasm, cytosol, endosome membrane, nucleolus, nucleus ATP binding, IkappaB kinase activity, NF-kappaB-inducing kinase activity, protein binding, protein kinase activity Human IKBKG HPA UniProtKB {GO:0005515=PMID:15474016, GO:0050852=Reactome:REACT_12526, GO:0034142=Reactome:REACT_6894, GO:0001782=GO_REF:0000019, GO:0008385=PMID:18626576, GO:0070423=Reactome:REACT_75776, GO:0007249=PMID:18626576, GO:0005634=PMID:14651848, GO:0051403=Reactome:REACT_21308, GO:0035872=Reactome:REACT_75913, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_118618, GO:0005622=GO_REF:0000054, GO:0002756=Reactome:REACT_6809, GO:0000187=Reactome:REACT_21399, GO:0005737=GO_REF:0000052, GO:0006955=PMID:9751060, GO:0051092=Reactome:REACT_21281, GO:0006954=PMID:18626576, GO:0002755=Reactome:REACT_27215, GO:0032481=Reactome:REACT_118823, GO:0004871=PMID:9927690, GO:0043123=Reactome:REACT_24918, GO:0034138=Reactome:REACT_6783, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0046982=GO_REF:0000019, GO:0007250=GO_REF:0000019, GO:0034134=Reactome:REACT_7980, GO:0019904=PMID:15341735, GO:0007254=Reactome:REACT_21368, GO:0006917=PMID:9927690, GO:0002224=Reactome:REACT_9020, GO:0009615=PMID:18626576, GO:0006974=PMID:14651848, GO:0006351=GO_REF:0000037, GO:0044444=PMID:11113112, GO:0019048=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0035666=Reactome:REACT_25281, GO:0034166=Reactome:REACT_9027, GO:0034146=Reactome:REACT_9061, GO:0034162=Reactome:REACT_9047} Q9Y6K9 NF-kappa-B essential modulator protein 20080818 {GO:0005515=IPI, GO:0050852=TAS, GO:0034142=TAS, GO:0001782=IEA, GO:0008385=TAS, GO:0070423=TAS, GO:0007249=TAS, GO:0005634=IDA, GO:0051403=TAS, GO:0035872=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0005622=IDA, GO:0002756=TAS, GO:0000187=TAS, GO:0005737=IDA, GO:0006955=TAS, GO:0051092=TAS, GO:0006954=TAS, GO:0002755=TAS, GO:0032481=TAS, GO:0004871=TAS, GO:0043123=TAS, GO:0034138=TAS, GO:0038124=TAS, GO:0038123=TAS, GO:0046982=IEA, GO:0007250=IEA, GO:0034134=TAS, GO:0019904=IPI, GO:0007254=TAS, GO:0006917=TAS, GO:0002224=TAS, GO:0009615=TAS, GO:0006974=IDA, GO:0006351=IEA, GO:0044444=IDA, GO:0019048=IEA, GO:0045087=TAS, GO:0035666=TAS, GO:0034166=TAS, GO:0034146=TAS, GO:0034162=TAS} B cell homeostasis, I-kappaB kinase/NF-kappaB cascade, JNK cascade, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, T cell receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, activation of MAPK activity, activation of NF-kappaB-inducing kinase activity, immune response, induction of apoptosis, inflammatory response, innate immune response, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, nucleotide-binding oligomerization domain containing signaling pathway, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of type I interferon production, response to DNA damage stimulus, response to virus, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, transcription, DNA-dependent, virus-host interaction IkappaB kinase complex, cytoplasm, cytoplasmic part, cytosol, intracellular, nucleus metal ion binding, protein binding, protein domain specific binding, protein heterodimerization activity, signal transducer activity Human IKZF1 PINC UniProtKB {GO:0003700=GO_REF:0000019, GO:0060041=GO_REF:0000019, GO:0048538=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0045660=GO_REF:0000019, GO:0048535=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0048541=GO_REF:0000019, GO:0051138=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0030183=GO_REF:0000019, GO:0001779=GO_REF:0000019, GO:0040018=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0003677=PMID:8543809, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000019, GO:0007049=GO_REF:0000037, GO:0005721=GO_REF:0000019, GO:0030217=GO_REF:0000019, GO:0048732=GO_REF:0000019, GO:0007498=PMID:8543809, GO:0008270=GO_REF:0000002, GO:0030900=GO_REF:0000019, GO:0016568=GO_REF:0000037} Q13422 DNA-binding protein Ikaros protein 20030904 {GO:0003700=IEA, GO:0060041=IEA, GO:0048538=IEA, GO:0005634=IEA, GO:0045660=IEA, GO:0048535=IEA, GO:0005737=IEA, GO:0048541=IEA, GO:0051138=IEA, GO:0045944=IEA, GO:0030183=IEA, GO:0001779=IEA, GO:0040018=IEA, GO:0046982=IEA, GO:0000122=IEA, GO:0003677=TAS, GO:0006351=IEA, GO:0043565=IEA, GO:0007049=IEA, GO:0005721=IEA, GO:0030217=IEA, GO:0048732=IEA, GO:0007498=TAS, GO:0008270=IEA, GO:0030900=IEA, GO:0016568=IEA} B cell differentiation, Peyer's patch development, T cell differentiation, cell cycle, chromatin modification, forebrain development, gland development, lymph node development, mesoderm development, natural killer cell differentiation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of NK T cell differentiation, positive regulation of multicellular organism growth, positive regulation of neutrophil differentiation, positive regulation of transcription from RNA polymerase II promoter, retina development in camera-type eye, thymus development, transcription, DNA-dependent centromeric heterochromatin, cytoplasm, nucleus DNA binding, protein heterodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human IKZF2 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0046982=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0005634=GO_REF:0000029, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0042803=GO_REF:0000019} Q9UKS7 Zinc finger protein Helios protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0046982=IEA, GO:0045944=IEA, GO:0005634=NAS, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0042803=IEA} biological_process, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding, molecular_function, nucleic acid binding, protein heterodimerization activity, protein homodimerization activity, zinc ion binding Human IKZF3 HPA UniProtKB {GO:0005515=PMID:20676092, GO:0045577=GO_REF:0000024, GO:0003700=PMID:10552935, GO:0005886=GO_REF:0000052, GO:0006357=PMID:10552935, GO:0046982=PMID:17646674, GO:0005634=GO_REF:0000052, GO:0030888=GO_REF:0000024, GO:0042981=PMID:10369681, GO:0006351=GO_REF:0000037, GO:0042803=PMID:17646674, GO:0043565=GO_REF:0000024, GO:0042113=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0045619=GO_REF:0000024, GO:0007498=PMID:10552935, GO:0008270=GO_REF:0000002} Q9UKT9 Zinc finger protein Aiolos protein 20120912 {GO:0005515=IPI, GO:0045577=ISS, GO:0003700=TAS, GO:0005886=IDA, GO:0006357=TAS, GO:0046982=IDA, GO:0005634=IDA, GO:0030888=ISS, GO:0042981=IMP, GO:0006351=IEA, GO:0042803=IDA, GO:0043565=ISS, GO:0042113=IEA, GO:0005737=IDA, GO:0045619=ISS, GO:0007498=TAS, GO:0008270=IEA} B cell activation, mesoderm development, regulation of B cell differentiation, regulation of B cell proliferation, regulation of apoptotic process, regulation of lymphocyte differentiation, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, nucleus, plasma membrane protein binding, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human IKZF4 UniProtKB UniProtKB {GO:0003700=PMID:10978333, GO:0046982=GO_REF:0000019, GO:0005634=PMID:10978333, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0045892=PMID:10978333, GO:0006351=GO_REF:0000037, GO:0042803=GO_REF:0000019} Q9H2S9 Zinc finger protein Eos protein 20010928 {GO:0003700=TAS, GO:0046982=IEA, GO:0005634=TAS, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0045892=TAS, GO:0006351=IEA, GO:0042803=IEA} negative regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding transcription factor activity, zinc ion binding Human IKZF5 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9H5V7 Zinc finger protein Pegasus protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 IL10 BHF-UCL UniProtKB {GO:0010468=PMID:9184696, GO:0032715=PMID:10443688, GO:0060670=GO_REF:0000019, GO:0005615=PMID:10443688, GO:0042130=PMID:14971032, GO:0045348=GO_REF:0000019, GO:0071392=GO_REF:0000019, GO:0045347=PMID:11244051, GO:0002904=PMID:9184696, GO:0044130=GO_REF:0000019, GO:0032689=GO_REF:0000019, GO:0042742=GO_REF:0000019, GO:0002875=GO_REF:0000019, GO:0032868=GO_REF:0000019, GO:0030886=GO_REF:0000019, GO:0045191=PMID:8228801, GO:0030595=PMID:9405662, GO:0042536=GO_REF:0000019, GO:0032720=GO_REF:0000019, GO:0030889=PMID:9184696, GO:0051384=PMID:10443688, GO:0005125=PMID:10443688, GO:0045355=PMID:9637497, GO:0045893=PMID:7749983, GO:0008083=PMID:1371884, GO:0051930=GO_REF:0000019, GO:0051045=PMID:18383040, GO:0007267=PMID:1847510, GO:0002237=PMID:17449476, GO:0050715=PMID:10443688, GO:0002740=PMID:10443688, GO:0042092=PMID:11244051, GO:0051091=PMID:7749983, GO:0006954=PMID:10443688, GO:0042100=PMID:8228801, GO:0045019=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0030183=PMID:8228801, GO:0034465=GO_REF:0000019, GO:0014854=GO_REF:0000019, GO:0030097=PMID:11244051, GO:0014823=GO_REF:0000019, GO:0043066=PMID:8312229, GO:0042493=GO_REF:0000019, GO:0007253=PMID:10975994, GO:0005141=PMID:1847510, GO:0071222=PMID:14971032, GO:0032695=GO_REF:0000019, GO:0032800=PMID:10443688} P22301 Interleukin-10 protein 20111125 {GO:0010468=IDA, GO:0032715=IDA, GO:0060670=IEA, GO:0005615=IDA, GO:0042130=NAS, GO:0045348=IEA, GO:0071392=IEA, GO:0045347=TAS, GO:0002904=IDA, GO:0044130=IEA, GO:0032689=IEA, GO:0042742=IEA, GO:0002875=IEA, GO:0032868=IEA, GO:0030886=IEA, GO:0045191=NAS, GO:0030595=TAS, GO:0042536=IEA, GO:0032720=IEA, GO:0030889=IDA, GO:0051384=IDA, GO:0005125=NAS, GO:0045355=NAS, GO:0045893=IDA, GO:0008083=NAS, GO:0051930=IEA, GO:0051045=IDA, GO:0007267=IC, GO:0002237=IDA, GO:0050715=IDA, GO:0002740=IDA, GO:0042092=TAS, GO:0051091=IDA, GO:0006954=IDA, GO:0042100=NAS, GO:0045019=IEA, GO:0045944=IEA, GO:0030183=NAS, GO:0034465=IEA, GO:0014854=IEA, GO:0030097=TAS, GO:0014823=IEA, GO:0043066=NAS, GO:0042493=IEA, GO:0007253=NAS, GO:0005141=NAS, GO:0071222=NAS, GO:0032695=IEA, GO:0032800=IDA} B cell differentiation, B cell proliferation, branching involved in labyrinthine layer morphogenesis, cell-cell signaling, cellular response to estradiol stimulus, cellular response to lipopolysaccharide, cytoplasmic sequestering of NF-kappaB, defense response to bacterium, hemopoiesis, inflammatory response, leukocyte chemotaxis, negative regulation of B cell proliferation, negative regulation of MHC class II biosynthetic process, negative regulation of T cell proliferation, negative regulation of apoptotic process, negative regulation of chronic inflammatory response to antigenic stimulus, negative regulation of cytokine secretion involved in immune response, negative regulation of growth of symbiont in host, negative regulation of interferon-alpha biosynthetic process, negative regulation of interferon-gamma production, negative regulation of interleukin-12 production, negative regulation of interleukin-6 production, negative regulation of membrane protein ectodomain proteolysis, negative regulation of myeloid dendritic cell activation, negative regulation of nitric oxide biosynthetic process, negative regulation of tumor necrosis factor biosynthetic process, negative regulation of tumor necrosis factor production, positive regulation of B cell apoptotic process, positive regulation of MHC class II biosynthetic process, positive regulation of cytokine secretion, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, receptor biosynthetic process, regulation of gene expression, regulation of isotype switching, regulation of sensory perception of pain, response to activity, response to carbon monoxide, response to drug, response to glucocorticoid stimulus, response to inactivity, response to insulin stimulus, response to molecule of bacterial origin, type 2 immune response extracellular space cytokine activity, growth factor activity, interleukin-10 receptor binding Human IL10RA GOC UniProtKB {GO:0005515=PMID:15837194, GO:0007165=PMID:8407942, GO:0004920=PMID:8120391, GO:0005886=PMID:8407942, GO:0004872=PMID:8407942, GO:0004871=PMID:8407942, GO:0016021=GO_REF:0000037} Q13651 Interleukin-10 receptor subunit alpha protein 20130413 {GO:0005515=IPI, GO:0007165=TAS, GO:0004920=TAS, GO:0005886=TAS, GO:0004872=TAS, GO:0004871=TAS, GO:0016021=IEA} signal transduction integral to membrane, plasma membrane interleukin-10 receptor activity, protein binding, receptor activity, signal transducer activity Human IL10RB PINC UniProtKB {GO:0005515=PMID:12483210, GO:0007165=PMID:10954742, GO:0006955=PMID:9463407, GO:0004920=PMID:10954742, GO:0006954=PMID:10954742, GO:0005886=PMID:10954742, GO:0032002=PMID:12483210, GO:0004872=PMID:8314576, GO:0016021=PMID:9312047} Q08334 Interleukin-10 receptor subunit beta protein 20030904 {GO:0005515=IPI, GO:0007165=TAS, GO:0006955=TAS, GO:0004920=TAS, GO:0006954=TAS, GO:0005886=TAS, GO:0032002=NAS, GO:0004872=TAS, GO:0016021=TAS} immune response, inflammatory response, signal transduction integral to membrane, interleukin-28 receptor complex, plasma membrane interleukin-10 receptor activity, protein binding, receptor activity Human IL11 MGI UniProtKB {GO:0008284=PMID:2145578, GO:0005142=PMID:2145578, GO:0007267=PMID:2145578, GO:0050731=PMID:7508917, GO:0030168=GO_REF:0000029, GO:0005576=PMID:2145578, GO:0005125=GO_REF:0000019, GO:0005615=GO_REF:0000037, GO:0046888=PMID:7867561, GO:0005737=GO_REF:0000019, GO:0033138=PMID:7508917, GO:0045944=PMID:7508917, GO:0030219=PMID:2145578, GO:0030183=PMID:2145578, GO:0045444=PMID:1828438, GO:0043410=PMID:7508917, GO:0008083=PMID:2145578} P20809 Interleukin-11 protein 20101104 {GO:0008284=IDA, GO:0005142=NAS, GO:0007267=IC, GO:0050731=IDA, GO:0030168=NAS, GO:0005576=IC, GO:0005125=IEA, GO:0005615=IEA, GO:0046888=IDA, GO:0005737=IEA, GO:0033138=IDA, GO:0045944=IDA, GO:0030219=NAS, GO:0030183=NAS, GO:0045444=NAS, GO:0043410=IDA, GO:0008083=IDA} B cell differentiation, cell-cell signaling, fat cell differentiation, megakaryocyte differentiation, negative regulation of hormone secretion, platelet activation, positive regulation of MAPK cascade, positive regulation of cell proliferation, positive regulation of peptidyl-serine phosphorylation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of transcription from RNA polymerase II promoter cytoplasm, extracellular region, extracellular space cytokine activity, growth factor activity, interleukin-11 receptor binding Human IL11RA GOC UniProtKB {GO:0007165=PMID:8786120, GO:0032502=PMID:21741611, GO:0004896=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0005887=PMID:7670098, GO:0007566=GO_REF:0000019, GO:0060322=PMID:21741611, GO:0004871=PMID:8786120, GO:0004888=PMID:7670098} Q14626 Interleukin-11 receptor subunit alpha protein 20130413 {GO:0007165=TAS, GO:0032502=IMP, GO:0004896=IEA, GO:0016020=IEA, GO:0005887=TAS, GO:0007566=IEA, GO:0060322=IMP, GO:0004871=TAS, GO:0004888=TAS} developmental process, embryo implantation, head development, signal transduction integral to plasma membrane, membrane cytokine receptor activity, signal transducer activity, transmembrane signaling receptor activity Human IL12A BHF-UCL UniProtKB {GO:0005515=PMID:10899108, GO:0050830=PMID:1357073, GO:0042520=PMID:12372421, GO:0005615=PMID:16456693, GO:0032816=PMID:1674604, GO:0045513=PMID:9342359, GO:0005737=GO_REF:0000019, GO:0006955=PMID:9789052, GO:0042102=GO_REF:0000019, GO:0051135=PMID:19088061, GO:0032496=PMID:8557999, GO:0007050=PMID:16942485, GO:0032729=PMID:19088061, GO:0042163=GO_REF:0000019, GO:0005143=PMID:1674604, GO:0046982=PMID:1674604, GO:0050671=PMID:2204066, GO:0042832=GO_REF:0000019, GO:0048662=PMID:16942485, GO:0005576=GO_REF:0000002, GO:0009615=PMID:16548883, GO:0005125=PMID:1674604, GO:0032700=PMID:16482511, GO:0045785=PMID:7903063, GO:0016477=PMID:7903063, GO:0043514=PMID:11114383, GO:0010224=PMID:8992506, GO:0001916=PMID:2204066, GO:0034393=PMID:16942485, GO:0045954=PMID:2204066, GO:0002860=PMID:7903063, GO:0008083=PMID:1674604} P29459 Interleukin-12 subunit alpha protein 20110111 {GO:0005515=IPI, GO:0050830=IEP, GO:0042520=IDA, GO:0005615=IDA, GO:0032816=IDA, GO:0045513=IPI, GO:0005737=IEA, GO:0006955=TAS, GO:0042102=IEA, GO:0051135=IDA, GO:0032496=IDA, GO:0007050=IDA, GO:0032729=IDA, GO:0042163=IEA, GO:0005143=NAS, GO:0046982=IPI, GO:0050671=IDA, GO:0042832=IEA, GO:0048662=IDA, GO:0005576=IEA, GO:0009615=IEP, GO:0005125=IDA, GO:0032700=IDA, GO:0045785=IDA, GO:0016477=IDA, GO:0043514=IDA, GO:0010224=IDA, GO:0001916=IDA, GO:0034393=IDA, GO:0045954=IDA, GO:0002860=IDA, GO:0008083=IDA} cell cycle arrest, cell migration, defense response to Gram-positive bacterium, defense response to protozoan, immune response, negative regulation of interleukin-17 production, negative regulation of smooth muscle cell proliferation, positive regulation of NK T cell activation, positive regulation of T cell mediated cytotoxicity, positive regulation of T cell proliferation, positive regulation of cell adhesion, positive regulation of interferon-gamma production, positive regulation of lymphocyte proliferation, positive regulation of natural killer cell activation, positive regulation of natural killer cell mediated cytotoxicity, positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, positive regulation of smooth muscle cell apoptotic process, positive regulation of tyrosine phosphorylation of Stat4 protein, response to UV-B, response to lipopolysaccharide, response to virus cytoplasm, extracellular region, extracellular space, interleukin-12 complex cytokine activity, growth factor activity, interleukin-12 beta subunit binding, interleukin-12 receptor binding, interleukin-27 binding, protein binding, protein heterodimerization activity Human IL12B BHF-UCL UniProtKB {GO:0005515=PMID:11114383, GO:2000318=GO_REF:0000024, GO:0032693=PMID:16751425, GO:0032819=PMID:19088061, GO:0005615=PMID:1673147, GO:0042803=GO_REF:0000019, GO:0032816=PMID:20027291, GO:0042802=PMID:7527811, GO:0051607=GO_REF:0000019, GO:0030101=PMID:1673147, GO:0045078=PMID:1673147, GO:0044130=GO_REF:0000019, GO:0045519=PMID:11114383, GO:0032729=PMID:19088061, GO:0004896=GO_REF:0000002, GO:0032760=PMID:16751425, GO:0032725=PMID:20027291, GO:0046982=PMID:1674604, GO:0042164=GO_REF:0000019, GO:0050671=PMID:1674604, GO:0042832=GO_REF:0000019, GO:0005125=PMID:1674604, GO:0045785=PMID:7903063, GO:0019953=PMID:16772281, GO:0071346=GO_REF:0000019, GO:0002230=GO_REF:0000024, GO:0051142=PMID:19088061, GO:0070743=PMID:11114383, GO:0008083=PMID:1674604, GO:0042346=PMID:20428758, GO:0002862=GO_REF:0000019, GO:0032733=PMID:15265908, GO:0042523=PMID:12023369, GO:0032735=PMID:20027291, GO:0042088=PMID:1673147, GO:0042520=PMID:19088061, GO:2000330=GO_REF:0000024, GO:0042093=PMID:1673147, GO:0042104=PMID:11114383, GO:0005737=GO_REF:0000019, GO:0043382=GO_REF:0000024, GO:0002827=GO_REF:0000024, GO:0042095=PMID:1673147, GO:0042102=PMID:12023369, GO:0051135=PMID:19088061, GO:0007050=PMID:16942485, GO:0010535=PMID:12023369, GO:0032740=PMID:16482511, GO:0005143=PMID:9603733, GO:0042517=PMID:12023369, GO:0045672=PMID:17888176, GO:0042510=PMID:12023369, GO:0048662=PMID:16942485, GO:0032700=PMID:16482511, GO:0050829=PMID:15114670, GO:0042035=PMID:1673147, GO:0071222=GO_REF:0000019, GO:0016477=PMID:7903063, GO:0016020=GO_REF:0000002, GO:0010224=PMID:8992506, GO:0043514=PMID:11114383, GO:0001916=GO_REF:0000024, GO:0034105=PMID:16482511, GO:0050729=PMID:16482511, GO:0034393=PMID:16942485, GO:0002860=PMID:7903063} P29460 Interleukin-12 subunit beta protein 20110111 {GO:0005515=IPI, GO:2000318=ISS, GO:0032693=IMP, GO:0032819=IDA, GO:0005615=TAS, GO:0042803=IEA, GO:0032816=IC, GO:0042802=IPI, GO:0051607=IEA, GO:0030101=IDA, GO:0045078=TAS, GO:0044130=IEA, GO:0045519=IDA, GO:0032729=IDA, GO:0004896=IEA, GO:0032760=IMP, GO:0032725=IDA, GO:0046982=IPI, GO:0042164=IEA, GO:0050671=IDA, GO:0042832=IEA, GO:0005125=IDA, GO:0045785=IDA, GO:0019953=TAS, GO:0071346=IEA, GO:0002230=ISS, GO:0051142=IDA, GO:0070743=IDA, GO:0008083=IDA, GO:0042346=TAS, GO:0002862=IEA, GO:0032733=IDA, GO:0042523=IDA, GO:0032735=IDA, GO:0042088=TAS, GO:0042520=IDA, GO:2000330=ISS, GO:0042093=IDA, GO:0042104=IDA, GO:0005737=IEA, GO:0043382=ISS, GO:0002827=ISS, GO:0042095=TAS, GO:0042102=IDA, GO:0051135=IDA, GO:0007050=IDA, GO:0010535=IDA, GO:0032740=IDA, GO:0005143=TAS, GO:0042517=IDA, GO:0045672=IDA, GO:0042510=IDA, GO:0048662=IDA, GO:0032700=IDA, GO:0050829=IDA, GO:0042035=TAS, GO:0071222=IEA, GO:0016477=IDA, GO:0016020=IEA, GO:0010224=IDA, GO:0043514=IDA, GO:0001916=ISS, GO:0034105=IC, GO:0050729=IC, GO:0034393=IDA, GO:0002860=IDA} T-helper 1 type immune response, T-helper cell differentiation, cell cycle arrest, cell migration, cellular response to interferon-gamma, cellular response to lipopolysaccharide, defense response to Gram-negative bacterium, defense response to protozoan, defense response to virus, interferon-gamma biosynthetic process, natural killer cell activation, negative regulation of growth of symbiont in host, negative regulation of inflammatory response to antigenic stimulus, negative regulation of interleukin-10 production, negative regulation of interleukin-17 production, negative regulation of smooth muscle cell proliferation, positive regulation of NF-kappaB import into nucleus, positive regulation of NK T cell activation, positive regulation of NK T cell proliferation, positive regulation of T cell mediated cytotoxicity, positive regulation of T cell proliferation, positive regulation of T-helper 1 type immune response, positive regulation of T-helper 17 cell lineage commitment, positive regulation of T-helper 17 type immune response, positive regulation of activated T cell proliferation, positive regulation of activation of JAK2 kinase activity, positive regulation of cell adhesion, positive regulation of defense response to virus by host, positive regulation of granulocyte macrophage colony-stimulating factor production, positive regulation of inflammatory response, positive regulation of interferon-gamma biosynthetic process, positive regulation of interferon-gamma production, positive regulation of interleukin-10 production, positive regulation of interleukin-12 production, positive regulation of interleukin-17 production, positive regulation of lymphocyte proliferation, positive regulation of memory T cell differentiation, positive regulation of natural killer cell activation, positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, positive regulation of natural killer cell proliferation, positive regulation of osteoclast differentiation, positive regulation of smooth muscle cell apoptotic process, positive regulation of tissue remodeling, positive regulation of tumor necrosis factor production, positive regulation of tyrosine phosphorylation of Stat3 protein, positive regulation of tyrosine phosphorylation of Stat4 protein, positive regulation of tyrosine phosphorylation of Stat5 protein, regulation of cytokine biosynthetic process, regulation of tyrosine phosphorylation of Stat1 protein, response to UV-B, sexual reproduction cytoplasm, extracellular space, interleukin-12 complex, interleukin-23 complex, membrane cytokine activity, cytokine receptor activity, growth factor activity, identical protein binding, interleukin-12 alpha subunit binding, interleukin-12 receptor binding, interleukin-23 receptor binding, protein binding, protein heterodimerization activity, protein homodimerization activity Human IL12RB1 GOC UniProtKB {GO:0032729=PMID:11114383, GO:2000318=GO_REF:0000024, GO:0038155=PMID:12023369, GO:0004896=PMID:8943050, GO:0072536=PMID:12023369, GO:0005143=PMID:12023369, GO:0019221=PMID:7911493, GO:0042020=PMID:12023369, GO:2000330=GO_REF:0000024, GO:0016517=PMID:8943050, GO:0007165=PMID:8943050, GO:0042104=PMID:11114383, GO:0071346=PMID:12023369, GO:0043382=GO_REF:0000024, GO:0042022=PMID:12023369, GO:0002230=GO_REF:0000024, GO:0002827=GO_REF:0000024, GO:0001916=GO_REF:0000024, GO:0035722=PMID:8943050, GO:0042019=PMID:12023369} P42701 Interleukin-12 receptor subunit beta-1 protein 20130413 {GO:0032729=IDA, GO:2000318=ISS, GO:0038155=IDA, GO:0004896=TAS, GO:0072536=IDA, GO:0005143=IPI, GO:0019221=TAS, GO:0042020=IDA, GO:2000330=ISS, GO:0016517=IDA, GO:0007165=IC, GO:0042104=IDA, GO:0071346=IDA, GO:0043382=ISS, GO:0042022=IDA, GO:0002230=ISS, GO:0002827=ISS, GO:0001916=ISS, GO:0035722=IDA, GO:0042019=IPI} cellular response to interferon-gamma, cytokine-mediated signaling pathway, interleukin-12-mediated signaling pathway, interleukin-23-mediated signaling pathway, positive regulation of T cell mediated cytotoxicity, positive regulation of T-helper 1 type immune response, positive regulation of T-helper 17 cell lineage commitment, positive regulation of T-helper 17 type immune response, positive regulation of activated T cell proliferation, positive regulation of defense response to virus by host, positive regulation of interferon-gamma production, positive regulation of memory T cell differentiation, signal transduction interleukin-12 receptor complex, interleukin-23 receptor complex cytokine receptor activity, interleukin-12 receptor activity, interleukin-12 receptor binding, interleukin-23 binding, interleukin-23 receptor activity Human IL12RB2 GOC UniProtKB {GO:0032729=PMID:11114383, GO:0008284=PMID:8943050, GO:0004896=PMID:8943050, GO:0019901=GO_REF:0000019, GO:0005887=PMID:8943050, GO:0019221=PMID:8943050, GO:0032496=GO_REF:0000019, GO:0018108=GO_REF:0000019, GO:0032609=GO_REF:0000019, GO:0007166=PMID:8943050, GO:0009897=GO_REF:0000019} Q99665 Interleukin-12 receptor subunit beta-2 protein 20130413 {GO:0032729=IDA, GO:0008284=TAS, GO:0004896=TAS, GO:0019901=IEA, GO:0005887=TAS, GO:0019221=TAS, GO:0032496=IEA, GO:0018108=IEA, GO:0032609=IEA, GO:0007166=TAS, GO:0009897=IEA} cell surface receptor signaling pathway, cytokine-mediated signaling pathway, interferon-gamma production, peptidyl-tyrosine phosphorylation, positive regulation of cell proliferation, positive regulation of interferon-gamma production, response to lipopolysaccharide external side of plasma membrane, integral to plasma membrane cytokine receptor activity, protein kinase binding Human IL13 BHF-UCL UniProtKB {GO:0005515=PMID:18243101, GO:1901247=PMID:20539013, GO:0043032=GO_REF:0000019, GO:0030890=GO_REF:0000019, GO:0042526=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0050714=GO_REF:0000019, GO:0007267=PMID:10725748, GO:0006928=PMID:10725748, GO:0005615=PMID:16275384, GO:0071635=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0006955=GO_REF:0000002, GO:0006954=PMID:8096327, GO:0002639=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0010155=GO_REF:0000019, GO:0051281=GO_REF:0000019, GO:0005144=GO_REF:0000019, GO:1901251=PMID:20539013, GO:0005576=PMID:20041150, GO:0032723=GO_REF:0000019, GO:0005125=GO_REF:0000037, GO:0048661=GO_REF:0000019, GO:0007165=PMID:10725748, GO:2000231=GO_REF:0000019, GO:0071345=GO_REF:0000019, GO:0071260=GO_REF:0000019, GO:0009897=GO_REF:0000019, GO:0035094=GO_REF:0000019} P35225 Interleukin-13 protein 20120808 {GO:0005515=IPI, GO:1901247=NAS, GO:0043032=IEA, GO:0030890=IEA, GO:0042526=IEA, GO:0045471=IEA, GO:0050714=IEA, GO:0007267=IC, GO:0006928=TAS, GO:0005615=ISS, GO:0071635=IEA, GO:0005737=IEA, GO:0006955=IEA, GO:0006954=TAS, GO:0002639=IEA, GO:0032496=IEA, GO:0010155=IEA, GO:0051281=IEA, GO:0005144=IEA, GO:1901251=NAS, GO:0005576=IDA, GO:0032723=IEA, GO:0005125=IEA, GO:0048661=IEA, GO:0007165=NAS, GO:2000231=IEA, GO:0071345=IEA, GO:0071260=IEA, GO:0009897=IEA, GO:0035094=IEA} cell-cell signaling, cellular component movement, cellular response to cytokine stimulus, cellular response to mechanical stimulus, immune response, inflammatory response, negative regulation of lung ciliated cell differentiation, negative regulation of transforming growth factor beta production, positive regulation of B cell proliferation, positive regulation of connective tissue growth factor production, positive regulation of immunoglobulin production, positive regulation of lung goblet cell differentiation, positive regulation of macrophage activation, positive regulation of pancreatic stellate cell proliferation, positive regulation of protein secretion, positive regulation of release of sequestered calcium ion into cytosol, positive regulation of smooth muscle cell proliferation, positive regulation of tyrosine phosphorylation of Stat6 protein, regulation of proton transport, response to ethanol, response to lipopolysaccharide, response to nicotine, signal transduction cytoplasm, external side of plasma membrane, extracellular region, extracellular space cytokine activity, interleukin-13 receptor binding, protein binding Human IL13RA1 InterPro UniProtKB {GO:0005515=PMID:18243101, GO:0004896=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0005886=PMID:9083087, GO:0005898=PMID:9013879, GO:0007166=PMID:9013879} Q9UDY5 Interleukin-13 receptor soluble form protein 20130413 {GO:0005515=IPI, GO:0004896=IEA, GO:0016020=IEA, GO:0005886=TAS, GO:0005898=TAS, GO:0007166=TAS} cell surface receptor signaling pathway interleukin-13 receptor complex, membrane, plasma membrane cytokine receptor activity, protein binding Human InterPro:IPR003532 IL13RA2 GOC UniProtKB {GO:0007165=PMID:9725226, GO:0004896=PMID:9725226, GO:0019221=PMID:9725226, GO:0004871=PMID:9725226, GO:0016021=GO_REF:0000037, GO:0005615=PMID:9083087} Q14627 Interleukin-13 receptor subunit alpha-2 protein 20130413 {GO:0007165=TAS, GO:0004896=TAS, GO:0019221=TAS, GO:0004871=TAS, GO:0016021=IEA, GO:0005615=TAS} cytokine-mediated signaling pathway, signal transduction extracellular space, integral to membrane cytokine receptor activity, signal transducer activity Human IL15 BHF-UCL UniProtKB {GO:0005515=PMID:16284400, GO:0008284=PMID:10851076, GO:0007267=PMID:7759105, GO:0005634=GO_REF:0000039, GO:0032819=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0071305=GO_REF:0000019, GO:0048535=GO_REF:0000019, GO:0005737=PMID:10851076, GO:0006955=GO_REF:0000002, GO:0006954=GO_REF:0000019, GO:0042102=GO_REF:0000019, GO:0045580=GO_REF:0000019, GO:0001779=GO_REF:0000019, GO:0048469=GO_REF:0000019, GO:0032740=PMID:16482511, GO:0005794=PMID:10851076, GO:0042517=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0014732=GO_REF:0000019, GO:0048662=GO_REF:0000019, GO:0005576=PMID:14718574, GO:0032825=GO_REF:0000019, GO:0001866=GO_REF:0000019, GO:0005125=GO_REF:0000019, GO:0005126=GO_REF:0000002, GO:0050691=GO_REF:0000019, GO:0007165=PMID:8178155, GO:0016020=PMID:10851076, GO:0005887=PMID:10851076, GO:0050778=GO_REF:0000019, GO:0034105=PMID:16482511, GO:0050729=PMID:16482511, GO:0045062=GO_REF:0000019, GO:0030212=GO_REF:0000019, GO:0005768=PMID:10851076} P40933 Interleukin-15 protein 20110111 {GO:0005515=IPI, GO:0008284=TAS, GO:0007267=TAS, GO:0005634=IEA, GO:0032819=IEA, GO:0005615=IEA, GO:0071305=IEA, GO:0048535=IEA, GO:0005737=TAS, GO:0006955=IEA, GO:0006954=IEA, GO:0042102=IEA, GO:0045580=IEA, GO:0001779=IEA, GO:0048469=IEA, GO:0032740=IDA, GO:0005794=TAS, GO:0042517=IEA, GO:0007568=IEA, GO:0014732=IEA, GO:0048662=IEA, GO:0005576=NAS, GO:0032825=IEA, GO:0001866=IEA, GO:0005125=IEA, GO:0005126=IEA, GO:0050691=IEA, GO:0007165=TAS, GO:0016020=TAS, GO:0005887=TAS, GO:0050778=IEA, GO:0034105=IC, GO:0050729=IC, GO:0045062=IEA, GO:0030212=IEA, GO:0005768=TAS} NK T cell proliferation, aging, cell maturation, cell-cell signaling, cellular response to vitamin D, extrathymic T cell selection, hyaluronan metabolic process, immune response, inflammatory response, lymph node development, natural killer cell differentiation, negative regulation of smooth muscle cell proliferation, positive regulation of T cell proliferation, positive regulation of cell proliferation, positive regulation of immune response, positive regulation of inflammatory response, positive regulation of interleukin-17 production, positive regulation of natural killer cell differentiation, positive regulation of natural killer cell proliferation, positive regulation of tissue remodeling, positive regulation of tyrosine phosphorylation of Stat3 protein, regulation of T cell differentiation, regulation of defense response to virus by host, signal transduction, skeletal muscle atrophy Golgi apparatus, cytoplasm, endosome, extracellular region, extracellular space, integral to plasma membrane, membrane, nucleus cytokine activity, cytokine receptor binding, protein binding Human GO:0032740 IL15RA GOC UniProtKB {GO:0005515=PMID:16284400, GO:0031965=GO_REF:0000039, GO:0004896=PMID:7641685, GO:0008283=PMID:8530383, GO:0019221=PMID:7641685, GO:0032825=GO_REF:0000019, GO:0005615=GO_REF:0000039, GO:0007165=PMID:8530383, GO:0000139=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0004871=PMID:8530383, GO:0030659=GO_REF:0000039} Q13261 Interleukin-15 receptor subunit alpha protein 20130413 {GO:0005515=IPI, GO:0031965=IEA, GO:0004896=TAS, GO:0008283=TAS, GO:0019221=TAS, GO:0032825=IEA, GO:0005615=IEA, GO:0007165=TAS, GO:0000139=IEA, GO:0005789=IEA, GO:0016021=IEA, GO:0004871=TAS, GO:0030659=IEA} cell proliferation, cytokine-mediated signaling pathway, positive regulation of natural killer cell differentiation, signal transduction Golgi membrane, cytoplasmic vesicle membrane, endoplasmic reticulum membrane, extracellular space, integral to membrane, nuclear membrane cytokine receptor activity, protein binding, signal transducer activity Human IL16 HPA UniProtKB {GO:0050930=GO_REF:0000019, GO:0005622=GO_REF:0000019, GO:0006955=PMID:9144227, GO:0006355=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0030595=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q14005 Pro-interleukin-16 protein 20101115 {GO:0050930=IEA, GO:0005622=IEA, GO:0006955=TAS, GO:0006355=IEA, GO:0005737=IDA, GO:0005886=IDA, GO:0030595=IEA, GO:0019048=IEA, GO:0005634=IDA, GO:0005615=IEA, GO:0005125=IEA, GO:0006351=IEA} immune response, induction of positive chemotaxis, leukocyte chemotaxis, regulation of transcription, DNA-dependent, transcription, DNA-dependent, virus-host interaction cytoplasm, extracellular space, intracellular, nucleus, plasma membrane cytokine activity Human IL17A BHF-UCL UniProtKB {GO:0008219=PMID:8390535, GO:0072537=PMID:21145111, GO:0007267=PMID:7499828, GO:0032747=PMID:21145111, GO:0006915=PMID:7499828, GO:0045672=PMID:17888176, GO:0005125=GO_REF:0000037, GO:0005615=GO_REF:0000019, GO:1900017=GO_REF:0000019, GO:0006955=PMID:7499828, GO:0006954=GO_REF:0000002, GO:0045944=PMID:16982811, GO:0071347=GO_REF:0000019, GO:0006486=PMID:7499828, GO:0009897=GO_REF:0000019} Q16552 Interleukin-17A protein 20110223 {GO:0008219=TAS, GO:0072537=IDA, GO:0007267=TAS, GO:0032747=IDA, GO:0006915=TAS, GO:0045672=IDA, GO:0005125=IEA, GO:0005615=IEA, GO:1900017=IEA, GO:0006955=TAS, GO:0006954=IEA, GO:0045944=IDA, GO:0071347=IEA, GO:0006486=TAS, GO:0009897=IEA} apoptotic process, cell death, cell-cell signaling, cellular response to interleukin-1, fibroblast activation, immune response, inflammatory response, positive regulation of cytokine production involved in inflammatory response, positive regulation of interleukin-23 production, positive regulation of osteoclast differentiation, positive regulation of transcription from RNA polymerase II promoter, protein glycosylation external side of plasma membrane, extracellular space cytokine activity Human IL17B PINC UniProtKB {GO:1900017=GO_REF:0000019, GO:0006955=PMID:10639155, GO:0006954=GO_REF:0000002, GO:0007267=PMID:10639155, GO:0005125=GO_REF:0000019, GO:0005615=GO_REF:0000037} Q9UHF5 Interleukin-17B protein 20030904 {GO:1900017=IEA, GO:0006955=TAS, GO:0006954=IEA, GO:0007267=TAS, GO:0005125=IEA, GO:0005615=IEA} cell-cell signaling, immune response, inflammatory response, positive regulation of cytokine production involved in inflammatory response extracellular space cytokine activity Human IL17F UniProtKB UniProtKB {GO:0045414=PMID:11574464, GO:0051216=PMID:11574464, GO:0045423=PMID:11574464, GO:0005576=PMID:11574464, GO:0045408=PMID:11574464, GO:0006029=PMID:11574464, GO:0042089=PMID:11591732, GO:0005615=GO_REF:0000019, GO:0005125=PMID:11591732, GO:0005126=GO_REF:0000019, GO:0042803=PMID:11574464, GO:1900017=GO_REF:0000019, GO:0006954=GO_REF:0000002, GO:0019955=PMID:11574464, GO:0045076=PMID:11591732, GO:0045944=GO_REF:0000019, GO:0016525=PMID:11591732, GO:0017015=PMID:11591732, GO:0042109=PMID:11591732} Q96PD4 Interleukin-17F protein 20040819 {GO:0045414=IDA, GO:0051216=IDA, GO:0045423=IDA, GO:0005576=NAS, GO:0045408=IDA, GO:0006029=IDA, GO:0042089=IDA, GO:0005615=IEA, GO:0005125=IDA, GO:0005126=IEA, GO:0042803=IDA, GO:1900017=IEA, GO:0006954=IEA, GO:0019955=IDA, GO:0045076=IDA, GO:0045944=IEA, GO:0016525=IDA, GO:0017015=IDA, GO:0042109=IDA} cartilage development, cytokine biosynthetic process, inflammatory response, lymphotoxin A biosynthetic process, negative regulation of angiogenesis, positive regulation of cytokine production involved in inflammatory response, positive regulation of transcription from RNA polymerase II promoter, proteoglycan metabolic process, regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, regulation of interleukin-2 biosynthetic process, regulation of interleukin-6 biosynthetic process, regulation of interleukin-8 biosynthetic process, regulation of transforming growth factor beta receptor signaling pathway extracellular region, extracellular space cytokine activity, cytokine binding, cytokine receptor binding, protein homodimerization activity Human IL17RA BHF-UCL UniProtKB {GO:0005515=PMID:21993848, GO:1900017=GO_REF:0000019, GO:0030368=PMID:9367539, GO:0072537=PMID:21145111, GO:0005887=PMID:9367539, GO:0032747=PMID:21145111, GO:0007166=PMID:9367539} Q96F46 Interleukin-17 receptor A protein 20110223 {GO:0005515=IPI, GO:1900017=IEA, GO:0030368=NAS, GO:0072537=IDA, GO:0005887=NAS, GO:0032747=IDA, GO:0007166=NAS} cell surface receptor signaling pathway, fibroblast activation, positive regulation of cytokine production involved in inflammatory response, positive regulation of interleukin-23 production integral to plasma membrane interleukin-17 receptor activity, protein binding Human IL17RB GOC UniProtKB {GO:0005737=GO_REF:0000019, GO:0004896=PMID:10815801, GO:0016020=PMID:10815801, GO:0009986=GO_REF:0000019, GO:0005887=PMID:10749887, GO:0019221=PMID:10815801, GO:0006952=PMID:10749887, GO:0005576=GO_REF:0000039, GO:0001558=PMID:10815801} Q9NRM6 Interleukin-17 receptor B protein 20130413 {GO:0005737=IEA, GO:0004896=NAS, GO:0016020=NAS, GO:0009986=IEA, GO:0005887=TAS, GO:0019221=NAS, GO:0006952=TAS, GO:0005576=IEA, GO:0001558=NAS} cytokine-mediated signaling pathway, defense response, regulation of cell growth cell surface, cytoplasm, extracellular region, integral to plasma membrane, membrane cytokine receptor activity Human IL17RC MGI UniProtKB {GO:1900017=GO_REF:0000019, GO:0030368=PMID:17911633, GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q8NAC3 Interleukin-17 receptor C protein 20120424 {GO:1900017=IEA, GO:0030368=IDA, GO:0005886=IEA, GO:0016021=IEA} positive regulation of cytokine production involved in inflammatory response integral to membrane, plasma membrane interleukin-17 receptor activity Human IL17RD UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0000139=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q8NFM7 Interleukin-17 receptor D protein 20130413 {GO:0005886=IEA, GO:0000139=IEA, GO:0016021=IEA} Golgi membrane, integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 IL18 BHF-UCL UniProtKB {GO:0070301=GO_REF:0000019, GO:0009409=GO_REF:0000019, GO:0032819=PMID:19088061, GO:0005615=GO_REF:0000019, GO:0030155=PMID:11477102, GO:0032757=GO_REF:0000019, GO:0043525=GO_REF:0000019, GO:0071356=GO_REF:0000019, GO:0032729=PMID:19088061, GO:0032760=GO_REF:0000019, GO:0032725=PMID:20027291, GO:0042253=PMID:10653850, GO:0030431=PMID:11506998, GO:0032722=GO_REF:0000019, GO:0048546=GO_REF:0000019, GO:0005125=PMID:11598150, GO:0001649=GO_REF:0000019, GO:0071346=GO_REF:0000019, GO:0032967=GO_REF:0000019, GO:0055093=GO_REF:0000019, GO:0051142=PMID:19088061, GO:0030324=GO_REF:0000019, GO:0032731=GO_REF:0000019, GO:0007267=PMID:9792649, GO:0042088=PMID:8766574, GO:0005829=Reactome:REACT_23994, GO:0042094=PMID:10653850, GO:0042104=PMID:8766574, GO:0016324=GO_REF:0000019, GO:0042092=PMID:11905033, GO:0006955=PMID:8999896, GO:0071374=GO_REF:0000019, GO:0071375=GO_REF:0000019, GO:0042095=PMID:10227975, GO:0050966=GO_REF:0000019, GO:0032930=GO_REF:0000019, GO:0009314=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0032740=PMID:16482511, GO:0005576=Reactome:REACT_23994, GO:0042231=PMID:10227975, GO:0001525=PMID:11466388, GO:0010628=GO_REF:0000019, GO:2000256=GO_REF:0000019, GO:0042033=PMID:11598150, GO:0034105=PMID:16482511, GO:0050729=PMID:16482511, GO:0071320=GO_REF:0000019, GO:0071260=GO_REF:0000019, GO:0043117=GO_REF:0000019, GO:2000504=GO_REF:0000019} Q14116 Interleukin-18 protein 20110111 {GO:0070301=IEA, GO:0009409=IEA, GO:0032819=IDA, GO:0005615=IEA, GO:0030155=IDA, GO:0032757=IEA, GO:0043525=IEA, GO:0071356=IEA, GO:0032729=IDA, GO:0032760=IEA, GO:0032725=IDA, GO:0042253=TAS, GO:0030431=ISS, GO:0032722=IEA, GO:0048546=IEA, GO:0005125=TAS, GO:0001649=IEA, GO:0071346=IEA, GO:0032967=IEA, GO:0055093=IEA, GO:0051142=IDA, GO:0030324=IEA, GO:0032731=IEA, GO:0007267=TAS, GO:0042088=IDA, GO:0005829=TAS, GO:0042094=TAS, GO:0042104=IDA, GO:0016324=IEA, GO:0042092=TAS, GO:0006955=TAS, GO:0071374=IEA, GO:0071375=IEA, GO:0042095=TAS, GO:0050966=IEA, GO:0032930=IEA, GO:0009314=IEA, GO:0001666=IEA, GO:0032740=IDA, GO:0005576=TAS, GO:0042231=TAS, GO:0001525=IDA, GO:0010628=IEA, GO:2000256=IEA, GO:0042033=TAS, GO:0034105=IC, GO:0050729=IC, GO:0071320=IEA, GO:0071260=IEA, GO:0043117=IEA, GO:2000504=IEA} T-helper 1 type immune response, angiogenesis, cell-cell signaling, cellular response to cAMP, cellular response to hydrogen peroxide, cellular response to interferon-gamma, cellular response to mechanical stimulus, cellular response to parathyroid hormone stimulus, cellular response to peptide hormone stimulus, cellular response to tumor necrosis factor, chemokine biosynthetic process, detection of mechanical stimulus involved in sensory perception of pain, digestive tract morphogenesis, granulocyte macrophage colony-stimulating factor biosynthetic process, immune response, interferon-gamma biosynthetic process, interleukin-13 biosynthetic process, interleukin-2 biosynthetic process, lung development, osteoblast differentiation, positive regulation of NK T cell proliferation, positive regulation of activated T cell proliferation, positive regulation of blood vessel remodeling, positive regulation of chemokine production, positive regulation of collagen biosynthetic process, positive regulation of gene expression, positive regulation of granulocyte macrophage colony-stimulating factor production, positive regulation of inflammatory response, positive regulation of interferon-gamma production, positive regulation of interleukin-1 beta production, positive regulation of interleukin-17 production, positive regulation of interleukin-8 production, positive regulation of male germ cell proliferation, positive regulation of natural killer cell proliferation, positive regulation of neuron apoptotic process, positive regulation of superoxide anion generation, positive regulation of tissue remodeling, positive regulation of tumor necrosis factor production, positive regulation of vascular permeability, regulation of cell adhesion, response to cold, response to hyperoxia, response to hypoxia, response to radiation, sleep, type 2 immune response apical plasma membrane, cytosol, extracellular region, extracellular space cytokine activity Human IL18BP GOC UniProtKB {GO:0070301=GO_REF:0000019, GO:1900116=PMID:11890646, GO:0071356=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0005576=PMID:10023777, GO:0042088=PMID:10023777, GO:0048019=PMID:11890646, GO:0005615=GO_REF:0000019, GO:0042007=PMID:10023777} O95998 Interleukin-18-binding protein protein 20130413 {GO:0070301=IEA, GO:1900116=TAS, GO:0071356=IEA, GO:0032496=IEA, GO:0005576=TAS, GO:0042088=IDA, GO:0048019=TAS, GO:0005615=IEA, GO:0042007=IDA} T-helper 1 type immune response, cellular response to hydrogen peroxide, cellular response to tumor necrosis factor, extracellular negative regulation of signal transduction, response to lipopolysaccharide extracellular region, extracellular space interleukin-18 binding, receptor antagonist activity Human IL18R1 PINC UniProtKB {GO:0007165=PMID:9325300, GO:0006955=PMID:9325300, GO:0005886=PMID:9325300, GO:0004908=GO_REF:0000002, GO:0004872=PMID:9325300, GO:0016021=GO_REF:0000037} Q13478 Interleukin-18 receptor 1 protein 20030904 {GO:0007165=TAS, GO:0006955=TAS, GO:0005886=TAS, GO:0004908=IEA, GO:0004872=TAS, GO:0016021=IEA} immune response, signal transduction integral to membrane, plasma membrane interleukin-1 receptor activity, receptor activity Human IL18RAP InterPro UniProtKB {GO:0007165=GO_REF:0000002, GO:0006955=PMID:9792649, GO:0006954=PMID:9792649, GO:0004872=PMID:9792649, GO:0016021=GO_REF:0000037, GO:0007166=PMID:9792649} Q3KPE8 Interleukin-18 receptor accessory protein protein 20130413 {GO:0007165=IEA, GO:0006955=TAS, GO:0006954=TAS, GO:0004872=TAS, GO:0016021=IEA, GO:0007166=TAS} cell surface receptor signaling pathway, immune response, inflammatory response, signal transduction integral to membrane receptor activity Human InterPro:IPR000157 IL19 UniProtKB UniProtKB {GO:0007165=PMID:11196675, GO:0006955=PMID:11196675, GO:0006915=GO_REF:0000037, GO:0005576=PMID:11196675, GO:0005125=PMID:11196675, GO:0005615=GO_REF:0000037} Q9UHD0 Interleukin-19 protein 20020614 {GO:0007165=NAS, GO:0006955=NAS, GO:0006915=IEA, GO:0005576=NAS, GO:0005125=TAS, GO:0005615=IEA} apoptotic process, immune response, signal transduction extracellular region, extracellular space cytokine activity Human IL1A BHF-UCL UniProtKB {GO:0005515=PMID:18329368, GO:0043066=PMID:10748004, GO:0005149=GO_REF:0000002, GO:0008285=PMID:3493774, GO:0008283=PMID:6209582, GO:0005507=PMID:12746488, GO:0019221=PMID:2989698, GO:0006915=PMID:1924307, GO:0045840=PMID:2989698, GO:0005576=Reactome:REACT_22435, GO:0050715=PMID:1739124, GO:0005125=PMID:2989698, GO:0005615=PMID:3493774, GO:0010575=GO_REF:0000024, GO:0045766=GO_REF:0000024, GO:0005829=PMID:12746488, GO:0034605=PMID:12746488, GO:0045086=PMID:2989698, GO:0006955=GO_REF:0000002, GO:0006954=PMID:6209582, GO:0045944=GO_REF:0000019, GO:0001660=GO_REF:0000037, GO:0051781=GO_REF:0000037, GO:0046688=PMID:12746488} P01583 Interleukin-1 alpha protein 20090112 {GO:0005515=IPI, GO:0043066=TAS, GO:0005149=IEA, GO:0008285=IDA, GO:0008283=TAS, GO:0005507=IDA, GO:0019221=IMP, GO:0006915=TAS, GO:0045840=IMP, GO:0005576=TAS, GO:0050715=IDA, GO:0005125=IMP, GO:0005615=IMP, GO:0010575=ISS, GO:0045766=ISS, GO:0005829=IDA, GO:0034605=IDA, GO:0045086=IMP, GO:0006955=IEA, GO:0006954=TAS, GO:0045944=IEA, GO:0001660=IEA, GO:0051781=IEA, GO:0046688=IDA} apoptotic process, cell proliferation, cellular response to heat, cytokine-mediated signaling pathway, fever generation, immune response, inflammatory response, negative regulation of apoptotic process, negative regulation of cell proliferation, positive regulation of angiogenesis, positive regulation of cell division, positive regulation of cytokine secretion, positive regulation of interleukin-2 biosynthetic process, positive regulation of mitosis, positive regulation of transcription from RNA polymerase II promoter, positive regulation vascular endothelial growth factor production, response to copper ion cytosol, extracellular region, extracellular space copper ion binding, cytokine activity, interleukin-1 receptor binding, protein binding Human IL1B BHF-UCL UniProtKB {GO:0032755=PMID:16865359, GO:0019221=PMID:10748004, GO:0046330=GO_REF:0000019, GO:0002711=PMID:1919436, GO:0005615=PMID:12483741, GO:0032757=PMID:19524870, GO:0031622=GO_REF:0000024, GO:0030730=PMID:19032770, GO:0071639=PMID:19524870, GO:0032496=GO_REF:0000019, GO:0001660=GO_REF:0000037, GO:0033198=GO_REF:0000019, GO:0034116=PMID:19281832, GO:0051781=GO_REF:0000037, GO:0043123=GO_REF:0000019, GO:0043122=PMID:10748004, GO:0032729=PMID:20027291, GO:0045410=GO_REF:0000019, GO:0032725=PMID:20027291, GO:0007566=PMID:16720713, GO:0071310=PMID:19158679, GO:0030593=GO_REF:0000019, GO:0019904=PMID:16575408, GO:0014805=PMID:16477012, GO:0045840=PMID:2989698, GO:0005125=PMID:2989698, GO:0045086=PMID:2989698, GO:0070487=PMID:15100360, GO:0008083=GO_REF:0000002, GO:0045833=PMID:16865359, GO:0045080=GO_REF:0000019, GO:0042346=PMID:18390750, GO:0030949=PMID:12958148, GO:0060559=PMID:17023519, GO:0050996=PMID:16865359, GO:0051044=PMID:18373975, GO:0050995=PMID:19032770, GO:0008285=PMID:3493774, GO:0007267=PMID:2989698, GO:0035066=PMID:20018936, GO:0045429=PMID:8383325, GO:0005829=Reactome:REACT_23994, GO:0046827=PMID:19281832, GO:0000187=PMID:10748004, GO:0051091=PMID:10748004, GO:0006955=GO_REF:0000002, GO:0060355=PMID:19281832, GO:0006954=PMID:10748004, GO:0051092=PMID:12958148, GO:0045944=GO_REF:0000019, GO:0043407=PMID:16865359, GO:0042102=PMID:1919436, GO:0030141=GO_REF:0000019, GO:0043066=PMID:10748004, GO:0005149=PMID:1919436, GO:0070164=PMID:16865359, GO:0046627=PMID:16865359, GO:0006915=PMID:9218611, GO:0005576=PMID:20041150, GO:0010829=PMID:16865359, GO:0035505=PMID:18390750, GO:0010575=GO_REF:0000024, GO:0035690=PMID:19158679, GO:0045766=GO_REF:0000024, GO:0007165=PMID:9218611, GO:0033129=PMID:20018936, GO:0050796=PMID:8383325, GO:0001934=PMID:10748004, GO:0032611=GO_REF:0000019, GO:0030213=PMID:15100360, GO:0032308=GO_REF:0000024, GO:0071260=PMID:19593445} P01584 Interleukin-1 beta protein 20101202 {GO:0032755=TAS, GO:0019221=IDA, GO:0046330=IEA, GO:0002711=IC, GO:0005615=IDA, GO:0032757=IDA, GO:0031622=ISS, GO:0030730=IDA, GO:0071639=IDA, GO:0032496=IEA, GO:0001660=IEA, GO:0033198=IEA, GO:0034116=NAS, GO:0051781=IEA, GO:0043123=IEA, GO:0043122=IDA, GO:0032729=IDA, GO:0045410=IEA, GO:0032725=IDA, GO:0007566=TAS, GO:0071310=IDA, GO:0030593=IEA, GO:0019904=IPI, GO:0014805=NAS, GO:0045840=IMP, GO:0005125=IMP, GO:0045086=IMP, GO:0070487=IDA, GO:0008083=IEA, GO:0045833=ISS, GO:0045080=IEA, GO:0042346=IDA, GO:0030949=IC, GO:0060559=IDA, GO:0050996=ISS, GO:0051044=IDA, GO:0050995=IDA, GO:0008285=IDA, GO:0007267=TAS, GO:0035066=NAS, GO:0045429=IDA, GO:0005829=TAS, GO:0046827=NAS, GO:0000187=IDA, GO:0051091=IDA, GO:0006955=IEA, GO:0060355=NAS, GO:0006954=IDA, GO:0051092=IDA, GO:0045944=IEA, GO:0043407=ISS, GO:0042102=IDA, GO:0030141=IEA, GO:0043066=IDA, GO:0005149=NAS, GO:0070164=ISS, GO:0046627=ISS, GO:0006915=TAS, GO:0005576=IDA, GO:0010829=ISS, GO:0035505=IDA, GO:0010575=ISS, GO:0035690=IDA, GO:0045766=ISS, GO:0007165=TAS, GO:0033129=NAS, GO:0050796=IDA, GO:0001934=IDA, GO:0032611=IEA, GO:0030213=IDA, GO:0032308=ISS, GO:0071260=IEP} activation of MAPK activity, apoptotic process, cell-cell signaling, cellular response to drug, cellular response to mechanical stimulus, cellular response to organic substance, cytokine-mediated signaling pathway, embryo implantation, fever generation, hyaluronan biosynthetic process, immune response, inflammatory response, interleukin-1 beta production, monocyte aggregation, negative regulation of MAP kinase activity, negative regulation of adiponectin secretion, negative regulation of apoptotic process, negative regulation of cell proliferation, negative regulation of glucose transport, negative regulation of insulin receptor signaling pathway, negative regulation of lipid catabolic process, negative regulation of lipid metabolic process, neutrophil chemotaxis, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of JNK cascade, positive regulation of NF-kappaB import into nucleus, positive regulation of NF-kappaB transcription factor activity, positive regulation of T cell mediated immunity, positive regulation of T cell proliferation, positive regulation of angiogenesis, positive regulation of calcidiol 1-monooxygenase activity, positive regulation of cell adhesion molecule production, positive regulation of cell division, positive regulation of chemokine biosynthetic process, positive regulation of fever generation, positive regulation of granulocyte macrophage colony-stimulating factor production, positive regulation of heterotypic cell-cell adhesion, positive regulation of histone acetylation, positive regulation of histone phosphorylation, positive regulation of interferon-gamma production, positive regulation of interleukin-2 biosynthetic process, positive regulation of interleukin-6 biosynthetic process, positive regulation of interleukin-6 production, positive regulation of interleukin-8 production, positive regulation of lipid catabolic process, positive regulation of membrane protein ectodomain proteolysis, positive regulation of mitosis, positive regulation of monocyte chemotactic protein-1 production, positive regulation of myosin light chain kinase activity, positive regulation of nitric oxide biosynthetic process, positive regulation of prostaglandin secretion, positive regulation of protein export from nucleus, positive regulation of protein phosphorylation, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, positive regulation of vascular endothelial growth factor receptor signaling pathway, positive regulation vascular endothelial growth factor production, regulation of I-kappaB kinase/NF-kappaB cascade, regulation of insulin secretion, response to ATP, response to lipopolysaccharide, sequestering of triglyceride, signal transduction, smooth muscle adaptation cytosol, extracellular region, extracellular space, secretory granule cytokine activity, growth factor activity, interleukin-1 receptor binding, protein domain specific binding Human IL1F10 UniProtKB UniProtKB {GO:0006955=GO_REF:0000002, GO:0005149=GO_REF:0000002, GO:0006954=GO_REF:0000002, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037} Q8WWZ1 Interleukin-1 family member 10 protein 20130413 {GO:0006955=IEA, GO:0005149=IEA, GO:0006954=IEA, GO:0005615=IEA, GO:0005125=IEA} immune response, inflammatory response extracellular space cytokine activity, interleukin-1 receptor binding Human UniProtKB-KW:KW-0202 IL1R1 BHF-UCL UniProtKB {GO:0005515=PMID:16286467, GO:0009986=GO_REF:0000019, GO:0005886=Reactome:REACT_22435, GO:0005576=GO_REF:0000039, GO:0005161=PMID:16477012, GO:0002020=GO_REF:0000019, GO:0004909=GO_REF:0000002, GO:0006955=PMID:9120302, GO:0016020=PMID:16477012, GO:0005887=PMID:2530587, GO:0004908=PMID:10383454, GO:0004871=PMID:2530587, GO:0007166=PMID:1833184, GO:0070498=PMID:10383454, GO:0070555=PMID:10383454, GO:0004888=PMID:2530587} P14778 Interleukin-1 receptor type 1 protein 20081124 {GO:0005515=IPI, GO:0009986=IEA, GO:0005886=TAS, GO:0005576=IEA, GO:0005161=IPI, GO:0002020=IEA, GO:0004909=IEA, GO:0006955=TAS, GO:0016020=IDA, GO:0005887=TAS, GO:0004908=IDA, GO:0004871=TAS, GO:0007166=TAS, GO:0070498=IDA, GO:0070555=IDA, GO:0004888=TAS} cell surface receptor signaling pathway, immune response, interleukin-1-mediated signaling pathway, response to interleukin-1 cell surface, extracellular region, integral to plasma membrane, membrane, plasma membrane interleukin-1 receptor activity, interleukin-1, Type I, activating receptor activity, platelet-derived growth factor receptor binding, protease binding, protein binding, signal transducer activity, transmembrane signaling receptor activity Human IL1R2 BHF-UCL UniProtKB {GO:0005515=PMID:1830582, GO:0006955=PMID:8898719, GO:0004910=GO_REF:0000002, GO:0005886=Reactome:REACT_22331, GO:0004908=PMID:10191101, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037} P27930 Interleukin-1 receptor type 2 protein 20110804 {GO:0005515=IPI, GO:0006955=TAS, GO:0004910=IEA, GO:0005886=TAS, GO:0004908=TAS, GO:0005576=IEA, GO:0016021=IEA} immune response extracellular region, integral to membrane, plasma membrane interleukin-1 receptor activity, interleukin-1, Type II, blocking receptor activity, protein binding Human UniProtKB:P18510 IL1RAP Reactome UniProtKB {GO:0042094=GO_REF:0000019, GO:0006955=PMID:9065432, GO:0006954=PMID:9065432, GO:0006461=PMID:7775431, GO:0005886=Reactome:REACT_22435, GO:0005887=PMID:7775431, GO:0004908=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0004871=PMID:9065432} Q9NPH3 Interleukin-1 receptor accessory protein protein 20091203 {GO:0042094=IEA, GO:0006955=TAS, GO:0006954=TAS, GO:0006461=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0004908=IEA, GO:0005576=IEA, GO:0004871=TAS} immune response, inflammatory response, interleukin-2 biosynthetic process, protein complex assembly extracellular region, integral to plasma membrane, plasma membrane interleukin-1 receptor activity, signal transducer activity Human IL1RAPL1 BHF-UCL UniProtKB {GO:0005515=PMID:21940441, GO:0030424=GO_REF:0000039, GO:0009986=GO_REF:0000024, GO:0005886=PMID:12783849, GO:0005245=GO_REF:0000024, GO:0005102=GO_REF:0000024, GO:0030425=GO_REF:0000024, GO:0045920=PMID:12783849, GO:0007165=GO_REF:0000002, GO:0019966=PMID:12783849, GO:0005737=GO_REF:0000039, GO:0097105=GO_REF:0000024, GO:0045211=PMID:21940441, GO:0030182=GO_REF:0000024, GO:0050775=GO_REF:0000024, GO:0010975=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0007157=GO_REF:0000024} Q9NZN1 Interleukin-1 receptor accessory protein-like 1 protein 20120503 {GO:0005515=IPI, GO:0030424=IEA, GO:0009986=ISS, GO:0005886=IDA, GO:0005245=ISS, GO:0005102=ISS, GO:0030425=ISS, GO:0045920=IDA, GO:0007165=IEA, GO:0019966=IDA, GO:0005737=IEA, GO:0097105=ISS, GO:0045211=NAS, GO:0030182=ISS, GO:0050775=ISS, GO:0010975=ISS, GO:0016021=IEA, GO:0007157=ISS} heterophilic cell-cell adhesion, negative regulation of exocytosis, neuron differentiation, positive regulation of dendrite morphogenesis, presynaptic membrane assembly, regulation of neuron projection development, signal transduction axon, cell surface, cytoplasm, dendrite, integral to membrane, plasma membrane, postsynaptic membrane interleukin-1 binding, protein binding, receptor binding, voltage-gated calcium channel activity Human IL1RL1 IntAct UniProtKB {GO:0005515=PMID:16286016, GO:0004896=PMID:10191101, GO:0032754=GO_REF:0000019, GO:0043032=GO_REF:0000019, GO:0002113=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0007165=PMID:1482686, GO:0006955=PMID:10527832, GO:0002114=GO_REF:0000019, GO:0004908=GO_REF:0000002, GO:0002826=GO_REF:0000019, GO:0050729=GO_REF:0000019, GO:0005057=PMID:1482686, GO:0016021=GO_REF:0000037, GO:0032689=GO_REF:0000019, GO:0009897=GO_REF:0000019, GO:0043124=GO_REF:0000019, GO:0090197=GO_REF:0000019} Q01638 Interleukin-1 receptor-like 1 protein 20130415 {GO:0005515=IPI, GO:0004896=TAS, GO:0032754=IEA, GO:0043032=IEA, GO:0002113=IEA, GO:0005576=IEA, GO:0007165=TAS, GO:0006955=NAS, GO:0002114=IEA, GO:0004908=IEA, GO:0002826=IEA, GO:0050729=IEA, GO:0005057=TAS, GO:0016021=IEA, GO:0032689=IEA, GO:0009897=IEA, GO:0043124=IEA, GO:0090197=IEA} immune response, negative regulation of I-kappaB kinase/NF-kappaB cascade, negative regulation of T-helper 1 type immune response, negative regulation of interferon-gamma production, positive regulation of chemokine secretion, positive regulation of inflammatory response, positive regulation of interleukin-5 production, positive regulation of macrophage activation, signal transduction external side of plasma membrane, extracellular region, integral to membrane cytokine receptor activity, interleukin-1 receptor activity, interleukin-33 binding, interleukin-33 receptor activity, protein binding, receptor signaling protein activity Human UniProtKB:O95760 IL1RL2 PINC UniProtKB {GO:0004909=GO_REF:0000002, GO:0007165=PMID:1833184, GO:0006968=PMID:8332913, GO:0005887=PMID:1833184, GO:0004908=PMID:1833184} Q9HB29 Interleukin-1 receptor-like 2 protein 20050308 {GO:0004909=IEA, GO:0007165=TAS, GO:0006968=TAS, GO:0005887=TAS, GO:0004908=TAS} cellular defense response, signal transduction integral to plasma membrane interleukin-1 receptor activity, interleukin-1, Type I, activating receptor activity Human IL1RN HPA UniProtKB {GO:0006629=GO_REF:0000019, GO:0002439=GO_REF:0000019, GO:0005886=Reactome:REACT_22331, GO:0014050=GO_REF:0000019, GO:0045352=PMID:1828071, GO:0005634=GO_REF:0000052, GO:0045353=PMID:1830582, GO:0005152=PMID:2139180, GO:0005151=PMID:1830582, GO:0005615=PMID:12483741, GO:0005150=PMID:1828071, GO:0005622=PMID:7629520, GO:0006955=PMID:7629520, GO:0005737=GO_REF:0000052, GO:0034115=PMID:2139180, GO:0007613=GO_REF:0000019, GO:0043507=GO_REF:0000019, GO:0005813=GO_REF:0000052, GO:0043066=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:2000660=PMID:2137200, GO:0042493=GO_REF:0000019, GO:0010243=GO_REF:0000019, GO:0051384=PMID:10443688, GO:0031982=GO_REF:0000019, GO:0030073=GO_REF:0000019} P18510 Interleukin-1 receptor antagonist protein protein 20101115 {GO:0006629=IEA, GO:0002439=IEA, GO:0005886=TAS, GO:0014050=IEA, GO:0045352=IDA, GO:0005634=IDA, GO:0045353=IDA, GO:0005152=IDA, GO:0005151=IPI, GO:0005615=IDA, GO:0005150=IPI, GO:0005622=NAS, GO:0006955=NAS, GO:0005737=IDA, GO:0034115=IDA, GO:0007613=IEA, GO:0043507=IEA, GO:0005813=IDA, GO:0043066=IEA, GO:0007565=IEA, GO:2000660=IDA, GO:0042493=IEA, GO:0010243=IEA, GO:0051384=IDA, GO:0031982=IEA, GO:0030073=IEA} chronic inflammatory response to antigenic stimulus, female pregnancy, immune response, insulin secretion, lipid metabolic process, memory, negative regulation of apoptotic process, negative regulation of glutamate secretion, negative regulation of heterotypic cell-cell adhesion, negative regulation of interleukin-1-mediated signaling pathway, positive regulation of JUN kinase activity, response to drug, response to glucocorticoid stimulus, response to organic nitrogen centrosome, cytoplasm, extracellular space, intracellular, nucleus, plasma membrane, vesicle interleukin-1 Type I receptor antagonist activity, interleukin-1 Type II receptor antagonist activity, interleukin-1 receptor antagonist activity, interleukin-1, Type I receptor binding, interleukin-1, Type II receptor binding Human IL2 BHF-UCL UniProtKB {GO:0008284=PMID:8476561, GO:0031851=GO_REF:0000019, GO:0005134=PMID:8262055, GO:0030890=PMID:9184696, GO:0030307=PMID:8476561, GO:0007267=PMID:8476561, GO:0042523=PMID:19088061, GO:0007204=GO_REF:0000019, GO:0005615=PMID:6608729, GO:0007205=GO_REF:0000019, GO:0042104=PMID:10072077, GO:0006955=PMID:2342538, GO:0030101=PMID:8476561, GO:0043208=GO_REF:0000019, GO:0002903=PMID:9184696, GO:0045944=GO_REF:0000019, GO:0046013=GO_REF:0000019, GO:0007155=PMID:10929056, GO:0045822=GO_REF:0000019, GO:0060999=GO_REF:0000019, GO:0032729=GO_REF:0000019, GO:0032740=PMID:16482511, GO:0043066=PMID:8476561, GO:0005576=Reactome:REACT_27317, GO:0005125=PMID:10072077, GO:0050672=GO_REF:0000019, GO:0019209=PMID:8476561, GO:0030217=PMID:8476561, GO:0034105=PMID:16482511, GO:0050728=GO_REF:0000019, GO:0050729=PMID:16482511, GO:0051024=GO_REF:0000019, GO:0030246=GO_REF:0000019, GO:0001933=GO_REF:0000019, GO:0048304=GO_REF:0000019, GO:0008083=PMID:8476561, GO:0045591=GO_REF:0000019} P60568 Interleukin-2 protein 20110111 {GO:0008284=TAS, GO:0031851=IEA, GO:0005134=IDA, GO:0030890=IDA, GO:0030307=TAS, GO:0007267=TAS, GO:0042523=IDA, GO:0007204=IEA, GO:0005615=TAS, GO:0007205=IEA, GO:0042104=IDA, GO:0006955=TAS, GO:0030101=TAS, GO:0043208=IEA, GO:0002903=IDA, GO:0045944=IEA, GO:0046013=IEA, GO:0007155=TAS, GO:0045822=IEA, GO:0060999=IEA, GO:0032729=IEA, GO:0032740=IDA, GO:0043066=TAS, GO:0005576=TAS, GO:0005125=IDA, GO:0050672=IEA, GO:0019209=TAS, GO:0030217=TAS, GO:0034105=IC, GO:0050728=IEA, GO:0050729=IC, GO:0051024=IEA, GO:0030246=IEA, GO:0001933=IEA, GO:0048304=IEA, GO:0008083=TAS, GO:0045591=IEA} T cell differentiation, cell adhesion, cell-cell signaling, elevation of cytosolic calcium ion concentration, immune response, natural killer cell activation, negative regulation of B cell apoptotic process, negative regulation of apoptotic process, negative regulation of heart contraction, negative regulation of inflammatory response, negative regulation of lymphocyte proliferation, negative regulation of protein phosphorylation, positive regulation of B cell proliferation, positive regulation of activated T cell proliferation, positive regulation of cell growth, positive regulation of cell proliferation, positive regulation of dendritic spine development, positive regulation of immunoglobulin secretion, positive regulation of inflammatory response, positive regulation of interferon-gamma production, positive regulation of interleukin-17 production, positive regulation of isotype switching to IgG isotypes, positive regulation of regulatory T cell differentiation, positive regulation of tissue remodeling, positive regulation of transcription from RNA polymerase II promoter, positive regulation of tyrosine phosphorylation of Stat5 protein, protein kinase C-activating G-protein coupled receptor signaling pathway, regulation of T cell homeostatic proliferation extracellular region, extracellular space carbohydrate binding, cytokine activity, glycosphingolipid binding, growth factor activity, interleukin-2 receptor binding, kappa-type opioid receptor binding, kinase activator activity Human IL20 UniProtKB UniProtKB {GO:0045606=PMID:11470428, GO:0045618=PMID:11470428, GO:0042517=PMID:11470428, GO:0050727=PMID:11470428, GO:0005102=GO_REF:0000002, GO:0005576=PMID:11470428, GO:0045517=PMID:11470428, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037} Q9NYY1 Interleukin-20 protein 20031031 {GO:0045606=TAS, GO:0045618=TAS, GO:0042517=TAS, GO:0050727=TAS, GO:0005102=IEA, GO:0005576=TAS, GO:0045517=TAS, GO:0005615=IEA, GO:0005125=IEA} positive regulation of epidermal cell differentiation, positive regulation of keratinocyte differentiation, positive regulation of tyrosine phosphorylation of Stat3 protein, regulation of inflammatory response extracellular region, extracellular space cytokine activity, interleukin-20 receptor binding, receptor binding Human IL20RA UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9UHF4 Interleukin-20 receptor subunit alpha protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 IL20RB ENSEMBL UniProtKB {GO:0032703=GO_REF:0000019, GO:0002437=GO_REF:0000019, GO:0032753=GO_REF:0000019, GO:0048873=GO_REF:0000019, GO:0032733=GO_REF:0000019, GO:0002765=GO_REF:0000019, GO:0001808=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0032689=GO_REF:0000019, GO:0042130=GO_REF:0000019} Q6UXL0 Interleukin-20 receptor subunit beta protein 20130413 {GO:0032703=IEA, GO:0002437=IEA, GO:0032753=IEA, GO:0048873=IEA, GO:0032733=IEA, GO:0002765=IEA, GO:0001808=IEA, GO:0016021=IEA, GO:0032689=IEA, GO:0042130=IEA} homeostasis of number of cells within a tissue, immune response-inhibiting signal transduction, inflammatory response to antigenic stimulus, negative regulation of T cell proliferation, negative regulation of interferon-gamma production, negative regulation of interleukin-2 production, negative regulation of type IV hypersensitivity, positive regulation of interleukin-10 production, positive regulation of interleukin-4 production integral to membrane Human Ensembl:ENSMUSP00000096057 IL21 BHF-UCL UniProtKB {GO:0032740=PMID:16482511, GO:0008284=PMID:17673207, GO:0032733=GO_REF:0000019, GO:0005134=PMID:12504082, GO:0030890=PMID:17673207, GO:0042517=PMID:17673207, GO:0002729=GO_REF:0000019, GO:0042511=PMID:17673207, GO:0032825=GO_REF:0000019, GO:0005125=GO_REF:0000037, GO:0005615=PMID:11081504, GO:0005126=PMID:15546387, GO:0007165=PMID:11081504, GO:0006955=GO_REF:0000002, GO:0034105=PMID:16482511, GO:0045078=PMID:15765404, GO:0050729=PMID:16482511, GO:0045954=GO_REF:0000019, GO:0042102=PMID:17673207, GO:0048469=PMID:14635054} Q9HBE4 Interleukin-21 protein 20110111 {GO:0032740=IDA, GO:0008284=IDA, GO:0032733=IEA, GO:0005134=IPI, GO:0030890=IDA, GO:0042517=IDA, GO:0002729=IEA, GO:0042511=IDA, GO:0032825=IEA, GO:0005125=IEA, GO:0005615=NAS, GO:0005126=TAS, GO:0007165=NAS, GO:0006955=IEA, GO:0034105=IC, GO:0045078=NAS, GO:0050729=IC, GO:0045954=IEA, GO:0042102=IDA, GO:0048469=IDA} cell maturation, immune response, positive regulation of B cell proliferation, positive regulation of T cell proliferation, positive regulation of cell proliferation, positive regulation of inflammatory response, positive regulation of interferon-gamma biosynthetic process, positive regulation of interleukin-10 production, positive regulation of interleukin-17 production, positive regulation of natural killer cell cytokine production, positive regulation of natural killer cell differentiation, positive regulation of natural killer cell mediated cytotoxicity, positive regulation of tissue remodeling, positive regulation of tyrosine phosphorylation of Stat1 protein, positive regulation of tyrosine phosphorylation of Stat3 protein, signal transduction extracellular space cytokine activity, cytokine receptor binding, interleukin-2 receptor binding Human GO:0032740 IL21R GOC UniProtKB {GO:0030101=PMID:11081504, GO:0016021=PMID:11081504, GO:0001532=PMID:11081504, GO:0038114=PMID:11081504} Q9HBE5 Interleukin-21 receptor protein 20130413 {GO:0030101=NAS, GO:0016021=NAS, GO:0001532=NAS, GO:0038114=NAS} interleukin-21-mediated signaling pathway, natural killer cell activation integral to membrane interleukin-21 receptor activity Human IL22 UniProtKB UniProtKB {GO:0006954=PMID:10954742, GO:0007267=PMID:10875937, GO:0005576=PMID:10875937, GO:0006953=PMID:11481447, GO:0045518=PMID:10875937, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037} Q9GZX6 Interleukin-22 protein 20040225 {GO:0006954=NAS, GO:0007267=IC, GO:0005576=IC, GO:0006953=NAS, GO:0045518=NAS, GO:0005615=IEA, GO:0005125=IEA} acute-phase response, cell-cell signaling, inflammatory response extracellular region, extracellular space cytokine activity, interleukin-22 receptor binding Human GO:0045518 IL22RA1 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0016020=GO_REF:0000029, GO:0004904=PMID:10875937, GO:0016021=GO_REF:0000037} Q8N6P7 Interleukin-22 receptor subunit alpha-1 protein 20061026 {GO:0008150=ND, GO:0016020=NAS, GO:0004904=TAS, GO:0016021=IEA} biological_process integral to membrane, membrane interferon receptor activity Human IL22RA2 UniProtKB UniProtKB {GO:0042018=PMID:11390454, GO:0042017=PMID:11390453, GO:0042516=GO_REF:0000024, GO:0005615=PMID:11390453, GO:0005829=GO_REF:0000019} Q969J5 Interleukin-22 receptor subunit alpha-2 protein 20050927 {GO:0042018=IDA, GO:0042017=IDA, GO:0042516=ISS, GO:0005615=NAS, GO:0005829=IEA} regulation of tyrosine phosphorylation of Stat3 protein cytosol, extracellular space interleukin-22 binding, interleukin-22 receptor activity Human IL23A BHF-UCL UniProtKB {GO:0042346=PMID:20428758, GO:2000318=GO_REF:0000024, GO:0048771=GO_REF:0000037, GO:0032733=PMID:15265908, GO:0032693=PMID:16751425, GO:0042523=PMID:12023369, GO:0032735=PMID:20027291, GO:0032819=PMID:19088061, GO:0042520=PMID:19088061, GO:2000330=GO_REF:0000024, GO:0032816=PMID:20027291, GO:0042104=PMID:11114383, GO:0051607=GO_REF:0000037, GO:0006954=GO_REF:0000037, GO:0042098=GO_REF:0000019, GO:0043382=GO_REF:0000024, GO:0045944=GO_REF:0000019, GO:0002827=GO_REF:0000024, GO:0042102=PMID:12023369, GO:0051135=PMID:19088061, GO:0045519=PMID:11114383, GO:0032729=PMID:17888176, GO:0010535=PMID:12023369, GO:0032740=PMID:17888176, GO:0032760=PMID:16751425, GO:0032725=PMID:20027291, GO:0042517=PMID:19088061, GO:0045672=PMID:17888176, GO:0042510=PMID:12023369, GO:0005125=GO_REF:0000037, GO:0050829=PMID:15114670, GO:0002230=PMID:12421946, GO:0001916=GO_REF:0000024, GO:0034105=PMID:16482511, GO:0045087=GO_REF:0000037, GO:0050729=PMID:16482511, GO:0090023=GO_REF:0000019, GO:0051142=PMID:19088061, GO:0070743=PMID:11114383} Q9NPF7 Interleukin-23 subunit alpha protein 20110113 {GO:0042346=TAS, GO:2000318=ISS, GO:0048771=IEA, GO:0032733=IDA, GO:0032693=IMP, GO:0042523=IDA, GO:0032735=IDA, GO:0032819=IDA, GO:0042520=IDA, GO:2000330=ISS, GO:0032816=IC, GO:0042104=IDA, GO:0051607=IEA, GO:0006954=IEA, GO:0042098=IEA, GO:0043382=ISS, GO:0045944=IEA, GO:0002827=ISS, GO:0042102=IDA, GO:0051135=IDA, GO:0045519=IDA, GO:0032729=IDA, GO:0010535=IDA, GO:0032740=IDA, GO:0032760=IMP, GO:0032725=IDA, GO:0042517=IDA, GO:0045672=IDA, GO:0042510=IDA, GO:0005125=IEA, GO:0050829=IDA, GO:0002230=IDA, GO:0001916=ISS, GO:0034105=IC, GO:0045087=IEA, GO:0050729=IC, GO:0090023=IEA, GO:0051142=IDA, GO:0070743=IDA} T cell proliferation, defense response to Gram-negative bacterium, defense response to virus, inflammatory response, innate immune response, negative regulation of interleukin-10 production, positive regulation of NF-kappaB import into nucleus, positive regulation of NK T cell activation, positive regulation of NK T cell proliferation, positive regulation of T cell mediated cytotoxicity, positive regulation of T cell proliferation, positive regulation of T-helper 1 type immune response, positive regulation of T-helper 17 cell lineage commitment, positive regulation of T-helper 17 type immune response, positive regulation of activated T cell proliferation, positive regulation of activation of JAK2 kinase activity, positive regulation of defense response to virus by host, positive regulation of granulocyte macrophage colony-stimulating factor production, positive regulation of inflammatory response, positive regulation of interferon-gamma production, positive regulation of interleukin-10 production, positive regulation of interleukin-12 production, positive regulation of interleukin-17 production, positive regulation of memory T cell differentiation, positive regulation of natural killer cell activation, positive regulation of natural killer cell proliferation, positive regulation of neutrophil chemotaxis, positive regulation of osteoclast differentiation, positive regulation of tissue remodeling, positive regulation of transcription from RNA polymerase II promoter, positive regulation of tumor necrosis factor production, positive regulation of tyrosine phosphorylation of Stat3 protein, positive regulation of tyrosine phosphorylation of Stat4 protein, positive regulation of tyrosine phosphorylation of Stat5 protein, regulation of tyrosine phosphorylation of Stat1 protein, tissue remodeling interleukin-23 complex cytokine activity, interleukin-23 receptor binding Human IL23R GOC UniProtKB {GO:2000318=GO_REF:0000024, GO:0038155=PMID:12023369, GO:0032693=PMID:16751425, GO:0042523=PMID:12023369, GO:0032735=PMID:20027291, GO:0032819=PMID:19088061, GO:0042520=PMID:19088061, GO:2000330=GO_REF:0000024, GO:0042104=PMID:11114383, GO:0006954=GO_REF:0000037, GO:0043382=GO_REF:0000024, GO:0002827=GO_REF:0000024, GO:0042102=PMID:12023369, GO:0051135=PMID:19088061, GO:0032496=PMID:12023369, GO:0034341=PMID:12023369, GO:0032729=PMID:19088061, GO:0010535=PMID:12023369, GO:0032740=PMID:17888176, GO:0072536=PMID:12023369, GO:0005143=PMID:12023369, GO:0032725=PMID:20027291, GO:0042517=PMID:19088061, GO:0042020=PMID:12023369, GO:0045672=PMID:17888176, GO:0042510=PMID:12023369, GO:0050829=PMID:15114670, GO:0002230=GO_REF:0000024, GO:0001916=GO_REF:0000024, GO:0042019=PMID:12023369} Q5VWK5 Interleukin-23 receptor protein 20130413 {GO:2000318=ISS, GO:0038155=IDA, GO:0032693=IMP, GO:0042523=IC, GO:0032735=IDA, GO:0032819=IC, GO:0042520=IC, GO:2000330=ISS, GO:0042104=IC, GO:0006954=IEA, GO:0043382=ISS, GO:0002827=ISS, GO:0042102=IC, GO:0051135=IC, GO:0032496=IDA, GO:0034341=IDA, GO:0032729=TAS, GO:0010535=IC, GO:0032740=IC, GO:0072536=IDA, GO:0005143=IPI, GO:0032725=IC, GO:0042517=IC, GO:0042020=IDA, GO:0045672=IC, GO:0042510=IC, GO:0050829=IC, GO:0002230=ISS, GO:0001916=ISS, GO:0042019=IPI} defense response to Gram-negative bacterium, inflammatory response, interleukin-23-mediated signaling pathway, negative regulation of interleukin-10 production, positive regulation of NK T cell activation, positive regulation of T cell mediated cytotoxicity, positive regulation of T cell proliferation, positive regulation of T-helper 1 type immune response, positive regulation of T-helper 17 cell lineage commitment, positive regulation of T-helper 17 type immune response, positive regulation of activated T cell proliferation, positive regulation of activation of JAK2 kinase activity, positive regulation of defense response to virus by host, positive regulation of granulocyte macrophage colony-stimulating factor production, positive regulation of interferon-gamma production, positive regulation of interleukin-12 production, positive regulation of interleukin-17 production, positive regulation of memory T cell differentiation, positive regulation of natural killer cell proliferation, positive regulation of osteoclast differentiation, positive regulation of tyrosine phosphorylation of Stat3 protein, positive regulation of tyrosine phosphorylation of Stat4 protein, positive regulation of tyrosine phosphorylation of Stat5 protein, regulation of tyrosine phosphorylation of Stat1 protein, response to interferon-gamma, response to lipopolysaccharide interleukin-23 receptor complex interleukin-12 receptor binding, interleukin-23 binding, interleukin-23 receptor activity Human IL24 ENSEMBL UniProtKB {GO:0030336=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0071222=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0033136=GO_REF:0000019, GO:0042517=GO_REF:0000019, GO:0042060=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0071353=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0005125=GO_REF:0000037} Q13007 Interleukin-24 protein 20130413 {GO:0030336=IEA, GO:0008284=IEA, GO:0071222=IEA, GO:0008285=IEA, GO:0033136=IEA, GO:0042517=IEA, GO:0042060=IEA, GO:0006915=IEA, GO:0071353=IEA, GO:0005615=IEA, GO:0005125=IEA} apoptotic process, cellular response to interleukin-4, cellular response to lipopolysaccharide, negative regulation of cell migration, negative regulation of cell proliferation, positive regulation of cell proliferation, positive regulation of tyrosine phosphorylation of Stat3 protein, serine phosphorylation of STAT3 protein, wound healing extracellular space cytokine activity Human Ensembl:ENSRNOP00000006106 IL25 UniProtKB UniProtKB {GO:0002437=GO_REF:0000019, GO:0008150=GO_REF:0000015, GO:0016020=GO_REF:0000029, GO:0045944=GO_REF:0000019, GO:0009620=GO_REF:0000019, GO:0030222=GO_REF:0000019, GO:0009624=GO_REF:0000019, GO:0005125=GO_REF:0000019, GO:0005615=GO_REF:0000037, GO:0030380=PMID:11058597} Q9H293 Interleukin-25 protein 20061026 {GO:0002437=IEA, GO:0008150=ND, GO:0016020=NAS, GO:0045944=IEA, GO:0009620=IEA, GO:0030222=IEA, GO:0009624=IEA, GO:0005125=IEA, GO:0005615=IEA, GO:0030380=TAS} biological_process, eosinophil differentiation, inflammatory response to antigenic stimulus, positive regulation of transcription from RNA polymerase II promoter, response to fungus, response to nematode extracellular space, membrane cytokine activity, interleukin-17E receptor binding Human IL26 PINC UniProtKB {GO:0051897=PMID:18483078, GO:0045944=PMID:18483078, GO:0007267=PMID:10729163, GO:0050680=PMID:18483078, GO:0032874=PMID:18483078, GO:0050715=PMID:18483078, GO:0070374=PMID:18483078, GO:0005125=PMID:18483078, GO:0005615=PMID:18483078, GO:0005829=PMID:18483078, GO:0046427=PMID:18483078} Q9NPH9 Interleukin-26 protein 20030904 {GO:0051897=IDA, GO:0045944=IDA, GO:0007267=TAS, GO:0050680=IDA, GO:0032874=IDA, GO:0050715=IDA, GO:0070374=IDA, GO:0005125=IDA, GO:0005615=IDA, GO:0005829=IDA, GO:0046427=IDA} cell-cell signaling, negative regulation of epithelial cell proliferation, positive regulation of ERK1 and ERK2 cascade, positive regulation of JAK-STAT cascade, positive regulation of cytokine secretion, positive regulation of protein kinase B signaling cascade, positive regulation of stress-activated MAPK cascade, positive regulation of transcription from RNA polymerase II promoter cytosol, extracellular space cytokine activity Human IL27 UniProtKB UniProtKB {GO:0050688=GO_REF:0000037, GO:0009617=GO_REF:0000019, GO:0006954=GO_REF:0000037, GO:0045078=PMID:12734330, GO:0045087=GO_REF:0000037, GO:0005102=GO_REF:0000024, GO:0042129=GO_REF:0000024, GO:0045625=PMID:12734330, GO:0045523=GO_REF:0000024, GO:0005125=GO_REF:0000037, GO:0005615=GO_REF:0000024} Q8NEV9 Interleukin-27 subunit alpha protein 20030709 {GO:0050688=IEA, GO:0009617=IEA, GO:0006954=IEA, GO:0045078=IDA, GO:0045087=IEA, GO:0005102=ISS, GO:0042129=ISS, GO:0045625=IDA, GO:0045523=ISS, GO:0005125=IEA, GO:0005615=ISS} inflammatory response, innate immune response, positive regulation of interferon-gamma biosynthetic process, regulation of T cell proliferation, regulation of T-helper 1 cell differentiation, regulation of defense response to virus, response to bacterium extracellular space cytokine activity, interleukin-27 receptor binding, receptor binding Human IL27RA PINC UniProtKB {GO:0048302=GO_REF:0000019, GO:0032729=GO_REF:0000019, GO:0006955=PMID:9600072, GO:0002829=GO_REF:0000019, GO:0005887=PMID:9600072, GO:0050830=GO_REF:0000019, GO:0002827=GO_REF:0000019, GO:0045509=GO_REF:0000019, GO:0007166=PMID:9600072, GO:0004888=PMID:9600072} Q6UWB1 Interleukin-27 receptor subunit alpha protein 20061106 {GO:0048302=IEA, GO:0032729=IEA, GO:0006955=TAS, GO:0002829=IEA, GO:0005887=TAS, GO:0050830=IEA, GO:0002827=IEA, GO:0045509=IEA, GO:0007166=TAS, GO:0004888=TAS} cell surface receptor signaling pathway, defense response to Gram-positive bacterium, immune response, negative regulation of type 2 immune response, positive regulation of T-helper 1 type immune response, positive regulation of interferon-gamma production, regulation of isotype switching to IgG isotypes integral to plasma membrane interleukin-27 receptor activity, transmembrane signaling receptor activity Human IL2RA Reactome UniProtKB {GO:0002437=GO_REF:0000019, GO:0050687=GO_REF:0000019, GO:0004911=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0005886=Reactome:REACT_27317, GO:0008283=PMID:2983318, GO:0006915=PMID:9096364, GO:0006924=GO_REF:0000019, GO:0019976=GO_REF:0000019, GO:0042130=GO_REF:0000019, GO:0042104=GO_REF:0000019, GO:0006955=PMID:9096364, GO:0050777=GO_REF:0000019, GO:0007219=GO_REF:0000019, GO:0050728=GO_REF:0000019, GO:0008144=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0046013=GO_REF:0000019, GO:0007166=PMID:2983318, GO:0009897=GO_REF:0000019, GO:0045582=GO_REF:0000019} P01589 Interleukin-2 receptor subunit alpha protein 20091211 {GO:0002437=IEA, GO:0050687=IEA, GO:0004911=IEA, GO:0043065=IEA, GO:0005886=TAS, GO:0008283=TAS, GO:0006915=TAS, GO:0006924=IEA, GO:0019976=IEA, GO:0042130=IEA, GO:0042104=IEA, GO:0006955=TAS, GO:0050777=IEA, GO:0007219=IEA, GO:0050728=IEA, GO:0008144=IEA, GO:0016021=IEA, GO:0046013=IEA, GO:0007166=TAS, GO:0009897=IEA, GO:0045582=IEA} Notch signaling pathway, activation-induced cell death of T cells, apoptotic process, cell proliferation, cell surface receptor signaling pathway, immune response, inflammatory response to antigenic stimulus, negative regulation of T cell proliferation, negative regulation of defense response to virus, negative regulation of immune response, negative regulation of inflammatory response, positive regulation of T cell differentiation, positive regulation of activated T cell proliferation, positive regulation of apoptotic process, regulation of T cell homeostatic proliferation external side of plasma membrane, integral to membrane, plasma membrane drug binding, interleukin-2 binding, interleukin-2 receptor activity Human IL2RB GOC UniProtKB {GO:0007165=PMID:2785715, GO:0043066=PMID:7736574, GO:0004911=PMID:7736574, GO:0006461=PMID:2467293, GO:0005886=Reactome:REACT_27317, GO:0005887=PMID:8514792, GO:0019048=GO_REF:0000037, GO:0019221=PMID:7736574, GO:0038110=PMID:7736574, GO:0019976=GO_REF:0000024, GO:0009897=GO_REF:0000024} P14784 Interleukin-2 receptor subunit beta protein 20130413 {GO:0007165=TAS, GO:0043066=IDA, GO:0004911=IDA, GO:0006461=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0019048=IEA, GO:0019221=IDA, GO:0038110=IDA, GO:0019976=ISS, GO:0009897=ISS} cytokine-mediated signaling pathway, interleukin-2-mediated signaling pathway, negative regulation of apoptotic process, protein complex assembly, signal transduction, virus-host interaction external side of plasma membrane, integral to plasma membrane, plasma membrane interleukin-2 binding, interleukin-2 receptor activity Human IL2RG InterPro UniProtKB {GO:0005515=PMID:8266077, GO:0004911=PMID:8266076, GO:0004896=GO_REF:0000002, GO:0004913=PMID:8266078, GO:0005886=Reactome:REACT_115695, GO:0004917=PMID:8266077, GO:0019976=GO_REF:0000024, GO:0007165=PMID:8266076, GO:0006955=PMID:8266078, GO:0016020=GO_REF:0000002, GO:0005887=PMID:8514792, GO:0019048=GO_REF:0000037, GO:0038111=PMID:8266077, GO:0038110=PMID:8266076, GO:0035771=PMID:8266078, GO:0009897=GO_REF:0000024} Q5FC12 IL2RG nirs variant 2 protein 20130413 {GO:0005515=IPI, GO:0004911=TAS, GO:0004896=IEA, GO:0004913=TAS, GO:0005886=TAS, GO:0004917=TAS, GO:0019976=ISS, GO:0007165=NAS, GO:0006955=TAS, GO:0016020=IEA, GO:0005887=TAS, GO:0019048=IEA, GO:0038111=TAS, GO:0038110=TAS, GO:0035771=TAS, GO:0009897=ISS} immune response, interleukin-2-mediated signaling pathway, interleukin-4-mediated signaling pathway, interleukin-7-mediated signaling pathway, signal transduction, virus-host interaction external side of plasma membrane, integral to plasma membrane, membrane, plasma membrane cytokine receptor activity, interleukin-2 binding, interleukin-2 receptor activity, interleukin-4 receptor activity, interleukin-7 receptor activity, protein binding Human InterPro:IPR003531 IL3 BHF-UCL UniProtKB {GO:0008284=GO_REF:0000024, GO:0005135=PMID:2544122, GO:0045740=PMID:9722506, GO:0007267=PMID:3497400, GO:0050731=GO_REF:0000024, GO:0042523=PMID:9722506, GO:0005576=Reactome:REACT_24024, GO:0005125=GO_REF:0000037, GO:0005615=GO_REF:0000024, GO:0007399=PMID:9736740, GO:0006955=GO_REF:0000002, GO:0008083=GO_REF:0000037, GO:0035162=PMID:21149635} P08700 Interleukin-3 protein 20080530 {GO:0008284=ISS, GO:0005135=TAS, GO:0045740=IDA, GO:0007267=TAS, GO:0050731=ISS, GO:0042523=IDA, GO:0005576=TAS, GO:0005125=IEA, GO:0005615=ISS, GO:0007399=TAS, GO:0006955=IEA, GO:0008083=IEA, GO:0035162=IDA} cell-cell signaling, embryonic hemopoiesis, immune response, nervous system development, positive regulation of DNA replication, positive regulation of cell proliferation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of tyrosine phosphorylation of Stat5 protein extracellular region, extracellular space cytokine activity, growth factor activity, interleukin-3 receptor binding Human IL31RA UniProtKB UniProtKB {GO:0043066=PMID:11877449, GO:0008284=PMID:11877449, GO:0004896=PMID:11877449, GO:0019901=PMID:11877449, GO:0005886=GO_REF:0000039, GO:0043031=PMID:11877449, GO:0042517=PMID:11877449, GO:0019221=PMID:11877449, GO:0003713=PMID:11877449, GO:0042523=PMID:11877449, GO:0006952=PMID:11877449, GO:0042592=PMID:11877449, GO:0007259=PMID:11877449, GO:0019955=PMID:11877449, GO:0000165=PMID:11877449, GO:0030225=PMID:11877449, GO:0030224=PMID:11877449, GO:0016021=PMID:11877449, GO:0045893=PMID:11877449, GO:0007169=PMID:11877449} Q8NI17 Interleukin-31 receptor subunit alpha protein 20031216 {GO:0043066=NAS, GO:0008284=IDA, GO:0004896=TAS, GO:0019901=NAS, GO:0005886=IEA, GO:0043031=NAS, GO:0042517=IEP, GO:0019221=TAS, GO:0003713=NAS, GO:0042523=IEP, GO:0006952=NAS, GO:0042592=NAS, GO:0007259=IEP, GO:0019955=NAS, GO:0000165=NAS, GO:0030225=NAS, GO:0030224=IEP, GO:0016021=NAS, GO:0045893=NAS, GO:0007169=NAS} JAK-STAT cascade, MAPK cascade, cytokine-mediated signaling pathway, defense response, homeostatic process, macrophage differentiation, monocyte differentiation, negative regulation of apoptotic process, negative regulation of macrophage activation, positive regulation of cell proliferation, positive regulation of transcription, DNA-dependent, positive regulation of tyrosine phosphorylation of Stat3 protein, positive regulation of tyrosine phosphorylation of Stat5 protein, transmembrane receptor protein tyrosine kinase signaling pathway integral to membrane, plasma membrane cytokine binding, cytokine receptor activity, protein kinase binding, transcription coactivator activity Human IL32 PINC UniProtKB {GO:0006955=PMID:1729377, GO:0006952=PMID:1729377, GO:0007155=PMID:1729377, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037} P24001 Interleukin-32 protein 20030904 {GO:0006955=TAS, GO:0006952=TAS, GO:0007155=TAS, GO:0005615=IEA, GO:0005125=IEA} cell adhesion, defense response, immune response extracellular space cytokine activity Human IL33 BHF-UCL UniProtKB {GO:0005515=PMID:16286016, GO:0030133=GO_REF:0000039, GO:0032755=GO_REF:0000019, GO:0032753=GO_REF:0000019, GO:0032754=GO_REF:0000019, GO:0043032=PMID:19841166, GO:0005694=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0032736=GO_REF:0000019, GO:0005125=PMID:19841166, GO:0005615=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0045944=PMID:19841166, GO:0002686=GO_REF:0000019, GO:0051025=GO_REF:0000019, GO:0050729=PMID:19841166, GO:0002826=GO_REF:0000019, GO:0051024=GO_REF:0000019, GO:0002830=GO_REF:0000019, GO:0032689=GO_REF:0000019, GO:0090197=PMID:19841166} O95760 Interleukin-33 protein 20101020 {GO:0005515=IPI, GO:0030133=IEA, GO:0032755=IEA, GO:0032753=IEA, GO:0032754=IEA, GO:0043032=IDA, GO:0005694=IEA, GO:0005634=IEA, GO:0032736=IEA, GO:0005125=IDA, GO:0005615=IEA, GO:0006351=IEA, GO:0045944=ISS, GO:0002686=IEA, GO:0051025=IEA, GO:0050729=ISS, GO:0002826=IEA, GO:0051024=IEA, GO:0002830=IEA, GO:0032689=IEA, GO:0090197=IDA} negative regulation of T-helper 1 type immune response, negative regulation of immunoglobulin secretion, negative regulation of interferon-gamma production, negative regulation of leukocyte migration, positive regulation of chemokine secretion, positive regulation of immunoglobulin secretion, positive regulation of inflammatory response, positive regulation of interleukin-13 production, positive regulation of interleukin-4 production, positive regulation of interleukin-5 production, positive regulation of interleukin-6 production, positive regulation of macrophage activation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of type 2 immune response, transcription, DNA-dependent chromosome, extracellular space, nucleus, transport vesicle cytokine activity, protein binding Human UniProtKB:Q8BVZ5 IL34 UniProtKB UniProtKB {GO:0008284=PMID:18467591, GO:0006954=GO_REF:0000037, GO:0045087=GO_REF:0000037, GO:0005157=PMID:18467591, GO:0001934=PMID:18467591, GO:0008083=GO_REF:0000037, GO:0005125=GO_REF:0000037, GO:0005615=PMID:18467591} Q6ZMJ4 Interleukin-34 protein 20080722 {GO:0008284=IDA, GO:0006954=IEA, GO:0045087=IEA, GO:0005157=IDA, GO:0001934=IDA, GO:0008083=IEA, GO:0005125=IEA, GO:0005615=IDA} inflammatory response, innate immune response, positive regulation of cell proliferation, positive regulation of protein phosphorylation extracellular space cytokine activity, growth factor activity, macrophage colony-stimulating factor receptor binding Human IL36RN GOC UniProtKB {GO:0005149=GO_REF:0000002, GO:0001960=PMID:10512743, GO:0005152=GO_REF:0000002, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037} Q9UBH0 Interleukin-36 receptor antagonist protein protein 20130413 {GO:0005149=IEA, GO:0001960=TAS, GO:0005152=IEA, GO:0005615=IEA, GO:0005125=IEA} negative regulation of cytokine-mediated signaling pathway extracellular space cytokine activity, interleukin-1 receptor antagonist activity, interleukin-1 receptor binding Human IL37 UniProtKB UniProtKB {GO:0006955=PMID:10744718, GO:0005149=PMID:10744718, GO:0006954=GO_REF:0000002, GO:0005576=PMID:10625660, GO:0005634=GO_REF:0000039, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037, GO:0005829=GO_REF:0000039} Q9NZH6 Interleukin-37 protein 20050308 {GO:0006955=NAS, GO:0005149=NAS, GO:0006954=IEA, GO:0005576=NAS, GO:0005634=IEA, GO:0005615=IEA, GO:0005125=IEA, GO:0005829=IEA} immune response, inflammatory response cytosol, extracellular region, extracellular space, nucleus cytokine activity, interleukin-1 receptor binding Human IL3RA GOC UniProtKB {GO:0038156=PMID:1833064, GO:0004896=GO_REF:0000002, GO:0005886=Reactome:REACT_23884, GO:0016020=GO_REF:0000002, GO:0004912=PMID:1833064, GO:0016021=GO_REF:0000037, GO:0036016=PMID:1833064} P26951 Interleukin-3 receptor subunit alpha protein 20130413 {GO:0038156=TAS, GO:0004896=IEA, GO:0005886=TAS, GO:0016020=IEA, GO:0004912=TAS, GO:0016021=IEA, GO:0036016=TAS} cellular response to interleukin-3, interleukin-3-mediated signaling pathway integral to membrane, membrane, plasma membrane cytokine receptor activity, interleukin-3 receptor activity Human IL4 IntAct UniProtKB {GO:0005515=PMID:18243101, GO:0014070=GO_REF:0000019, GO:0048295=GO_REF:0000024, GO:0043031=GO_REF:0000019, GO:0005615=PMID:11418631, GO:0045348=GO_REF:0000024, GO:0006935=PMID:10725748, GO:0035745=PMID:20554961, GO:0007565=GO_REF:0000019, GO:0045191=PMID:11418631, GO:0071288=GO_REF:0000019, GO:2000320=GO_REF:0000019, GO:0002674=GO_REF:0000019, GO:0005125=GO_REF:0000019, GO:0002227=GO_REF:0000019, GO:0050776=GO_REF:0000024, GO:0045893=PMID:19346497, GO:0008083=PMID:11418631, GO:0048304=GO_REF:0000024, GO:0045892=PMID:18579517, GO:0009897=GO_REF:0000019, GO:0045080=GO_REF:0000019, GO:0005136=PMID:11418631, GO:0032733=GO_REF:0000019, GO:0030890=GO_REF:0000024, GO:0045471=GO_REF:0000019, GO:0031296=GO_REF:0000019, GO:0042523=GO_REF:0000019, GO:0045189=PMID:11967989, GO:0032736=PMID:19346497, GO:0097028=PMID:21149635, GO:0042104=GO_REF:0000019, GO:0006955=PMID:3016727, GO:0051091=GO_REF:0000019, GO:0042092=PMID:11676128, GO:0045019=GO_REF:0000019, GO:0002677=GO_REF:0000019, GO:0045944=GO_REF:0000024, GO:0042102=GO_REF:0000024, GO:0030183=PMID:11418631, GO:0010155=GO_REF:0000019, GO:0034097=GO_REF:0000019, GO:0045582=PMID:20554961, GO:0008203=PMID:11971948, GO:0043066=GO_REF:0000024, GO:0007584=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0045671=GO_REF:0000024, GO:0042325=GO_REF:0000024, GO:0006968=PMID:10725748, GO:0045064=GO_REF:0000019, GO:0002296=GO_REF:0000019} P05112 Interleukin-4 protein 20130415 {GO:0005515=IPI, GO:0014070=IEA, GO:0048295=ISS, GO:0043031=IEA, GO:0005615=TAS, GO:0045348=ISS, GO:0006935=TAS, GO:0035745=IDA, GO:0007565=IEA, GO:0045191=TAS, GO:0071288=IEA, GO:2000320=IEA, GO:0002674=IEA, GO:0005125=IEA, GO:0002227=IEA, GO:0050776=ISS, GO:0045893=IDA, GO:0008083=NAS, GO:0048304=ISS, GO:0045892=IDA, GO:0009897=IEA, GO:0045080=IEA, GO:0005136=TAS, GO:0032733=IEA, GO:0030890=ISS, GO:0045471=IEA, GO:0031296=IEA, GO:0042523=IEA, GO:0045189=TAS, GO:0032736=IDA, GO:0097028=IDA, GO:0042104=IEA, GO:0006955=TAS, GO:0051091=IEA, GO:0042092=TAS, GO:0045019=IEA, GO:0002677=IEA, GO:0045944=ISS, GO:0042102=ISS, GO:0030183=TAS, GO:0010155=IEA, GO:0034097=IEA, GO:0045582=IDA, GO:0008203=ISS, GO:0043066=ISS, GO:0007584=IEA, GO:0042493=IEA, GO:0045671=ISS, GO:0042325=ISS, GO:0006968=TAS, GO:0045064=IEA, GO:0002296=IEA} B cell costimulation, B cell differentiation, T-helper 1 cell lineage commitment, T-helper 2 cell cytokine production, T-helper 2 cell differentiation, cellular defense response, cellular response to mercury ion, chemotaxis, cholesterol metabolic process, connective tissue growth factor biosynthetic process, dendritic cell differentiation, female pregnancy, immune response, innate immune response in mucosa, negative regulation of T-helper 17 cell differentiation, negative regulation of acute inflammatory response, negative regulation of apoptotic process, negative regulation of chronic inflammatory response, negative regulation of macrophage activation, negative regulation of nitric oxide biosynthetic process, negative regulation of osteoclast differentiation, negative regulation of transcription, DNA-dependent, positive regulation of B cell proliferation, positive regulation of MHC class II biosynthetic process, positive regulation of T cell differentiation, positive regulation of T cell proliferation, positive regulation of activated T cell proliferation, positive regulation of chemokine biosynthetic process, positive regulation of interleukin-10 production, positive regulation of interleukin-13 production, positive regulation of isotype switching to IgE isotypes, positive regulation of isotype switching to IgG isotypes, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of tyrosine phosphorylation of Stat5 protein, regulation of immune response, regulation of isotype switching, regulation of phosphorylation, regulation of proton transport, response to cytokine stimulus, response to drug, response to ethanol, response to nutrient, response to organic cyclic compound, type 2 immune response external side of plasma membrane, extracellular space cytokine activity, growth factor activity, interleukin-4 receptor binding, protein binding Human UniProtKB:P78552 IL4R GOC UniProtKB {GO:0005515=PMID:18243101, GO:0043627=GO_REF:0000019, GO:0004896=GO_REF:0000002, GO:0004913=PMID:2307934, GO:0043032=GO_REF:0000019, GO:0002532=GO_REF:0000002, GO:0043560=PMID:19641626, GO:0005615=GO_REF:0000019, GO:0007165=PMID:2307934, GO:0006955=PMID:2307934, GO:0016020=GO_REF:0000002, GO:0005887=PMID:2307934, GO:0042127=GO_REF:0000019, GO:0045626=GO_REF:0000019, GO:0035771=PMID:2307934, GO:0005057=PMID:2307934, GO:0016021=GO_REF:0000002, GO:0045630=GO_REF:0000019, GO:0030728=GO_REF:0000019, GO:0090197=GO_REF:0000019} P24394 Interleukin-4 receptor subunit alpha protein 20130413 {GO:0005515=IPI, GO:0043627=IEA, GO:0004896=IEA, GO:0004913=TAS, GO:0043032=IEA, GO:0002532=IEA, GO:0043560=RCA, GO:0005615=IEA, GO:0007165=TAS, GO:0006955=TAS, GO:0016020=IEA, GO:0005887=TAS, GO:0042127=IEA, GO:0045626=IEA, GO:0035771=TAS, GO:0005057=TAS, GO:0016021=IEA, GO:0045630=IEA, GO:0030728=IEA, GO:0090197=IEA} immune response, interleukin-4-mediated signaling pathway, negative regulation of T-helper 1 cell differentiation, ovulation, positive regulation of T-helper 2 cell differentiation, positive regulation of chemokine secretion, positive regulation of macrophage activation, production of molecular mediator involved in inflammatory response, regulation of cell proliferation, response to estrogen stimulus, signal transduction extracellular space, integral to membrane, integral to plasma membrane, membrane cytokine receptor activity, insulin receptor substrate binding, interleukin-4 receptor activity, protein binding, receptor signaling protein activity Human IL5 BHF-UCL UniProtKB {GO:0005515=PMID:1495999, GO:0071803=PMID:15220135, GO:0005137=GO_REF:0000019, GO:0030890=GO_REF:0000019, GO:0019221=GO_REF:0000019, GO:0050731=GO_REF:0000024, GO:0005576=PMID:20041150, GO:0005615=PMID:3024129, GO:0005125=GO_REF:0000019, GO:0046427=GO_REF:0000019, GO:0006955=GO_REF:0000002, GO:0051091=GO_REF:0000019, GO:0006954=GO_REF:0000019, GO:0045645=GO_REF:0000019, GO:0051024=GO_REF:0000019, GO:0045893=GO_REF:0000019, GO:0008083=GO_REF:0000037} P05113 Interleukin-5 protein 20110220 {GO:0005515=IPI, GO:0071803=IDA, GO:0005137=IEA, GO:0030890=IEA, GO:0019221=IEA, GO:0050731=ISS, GO:0005576=IDA, GO:0005615=TAS, GO:0005125=IEA, GO:0046427=IEA, GO:0006955=IEA, GO:0051091=IEA, GO:0006954=IEA, GO:0045645=IEA, GO:0051024=IEA, GO:0045893=IEA, GO:0008083=IEA} cytokine-mediated signaling pathway, immune response, inflammatory response, positive regulation of B cell proliferation, positive regulation of JAK-STAT cascade, positive regulation of eosinophil differentiation, positive regulation of immunoglobulin secretion, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of podosome assembly, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription, DNA-dependent extracellular region, extracellular space cytokine activity, growth factor activity, interleukin-5 receptor binding, protein binding Human IL5RA GOC UniProtKB {GO:0002437=GO_REF:0000019, GO:0005515=PMID:1495999, GO:0004896=GO_REF:0000002, GO:0005886=Reactome:REACT_24024, GO:0008283=PMID:1732409, GO:0071310=GO_REF:0000019, GO:0038043=PMID:1495999, GO:0004914=PMID:1495999, GO:0005615=PMID:1495999, GO:0007165=PMID:1732409, GO:0016020=GO_REF:0000002, GO:0032674=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q01344 Interleukin-5 receptor subunit alpha protein 20130413 {GO:0002437=IEA, GO:0005515=IPI, GO:0004896=IEA, GO:0005886=TAS, GO:0008283=TAS, GO:0071310=IEA, GO:0038043=TAS, GO:0004914=TAS, GO:0005615=TAS, GO:0007165=TAS, GO:0016020=IEA, GO:0032674=IEA, GO:0016021=IEA} cell proliferation, cellular response to organic substance, inflammatory response to antigenic stimulus, interleukin-5-mediated signaling pathway, regulation of interleukin-5 production, signal transduction extracellular space, integral to membrane, membrane, plasma membrane cytokine receptor activity, interleukin-5 receptor activity, protein binding Human IL6 BHF-UCL UniProtKB {GO:0032755=PMID:10510402, GO:0050830=PMID:16034137, GO:0050731=PMID:7508917, GO:0051971=GO_REF:0000019, GO:0005615=PMID:10443688, GO:0046888=GO_REF:0000019, GO:0051607=PMID:3023045, GO:0051602=GO_REF:0000019, GO:0045079=GO_REF:0000024, GO:0046677=GO_REF:0000019, GO:0032868=GO_REF:0000019, GO:0045740=GO_REF:0000019, GO:0042832=GO_REF:0000019, GO:1901215=GO_REF:0000019, GO:0030168=PMID:7831669, GO:0005896=PMID:2261637, GO:0006953=PMID:12832423, GO:0005125=PMID:10443688, GO:0048635=GO_REF:0000019, GO:0042110=GO_REF:0000019, GO:0032966=PMID:12419823, GO:0016049=GO_REF:0000019, GO:0045454=GO_REF:0000019, GO:0060445=GO_REF:0000019, GO:0001781=PMID:7595060, GO:0050710=GO_REF:0000019, GO:0046716=GO_REF:0000019, GO:0051091=PMID:7749983, GO:0006955=GO_REF:0000002, GO:0033138=PMID:7508917, GO:0051092=PMID:12419823, GO:0006954=PMID:10443688, GO:0002675=PMID:2444978, GO:0060664=GO_REF:0000019, GO:0002384=PMID:2444978, GO:0006959=PMID:3491322, GO:0042102=PMID:3130269, GO:0043154=GO_REF:0000019, GO:0043200=GO_REF:0000019, GO:0045721=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0042517=PMID:12643274, GO:0009611=GO_REF:0000019, GO:0005576=Reactome:REACT_27309, GO:0042981=PMID:9949178, GO:0045727=PMID:16732314, GO:0048661=PMID:10510402, GO:0002690=PMID:16034137, GO:0010888=PMID:16464856, GO:0009612=GO_REF:0000019, GO:0045669=PMID:12372336, GO:0045666=GO_REF:0000019, GO:0051024=PMID:3491322, GO:0032494=PMID:16034137, GO:0033160=GO_REF:0000019, GO:0070301=PMID:19168699, GO:0009408=GO_REF:0000019, GO:0045599=PMID:16464856, GO:0008360=GO_REF:0000019, GO:0009409=GO_REF:0000019, GO:0019221=PMID:2261637, GO:0031175=PMID:3264880, GO:0046849=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0031667=GO_REF:0000019, GO:0070102=PMID:12552091, GO:0070374=GO_REF:0000019, GO:0050679=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0051384=PMID:10443688, GO:0032722=PMID:10510402, GO:0051592=GO_REF:0000019, GO:0050871=PMID:3491322, GO:0045893=PMID:7749983, GO:0008083=PMID:2261637, GO:0009897=GO_REF:0000019, GO:0005138=PMID:12829785, GO:0051897=GO_REF:0000019, GO:0008284=PMID:18719127, GO:0008285=GO_REF:0000019, GO:0045188=GO_REF:0000019, GO:0045429=GO_REF:0000019, GO:0031000=GO_REF:0000019, GO:0045944=PMID:17324931, GO:0070091=PMID:18719127, GO:0045630=GO_REF:0000019, GO:2000366=PMID:17324931, GO:0043066=PMID:18719127, GO:0002446=PMID:16034137, GO:0045765=PMID:8557680, GO:0010574=PMID:8557680, GO:0002548=PMID:10510402, GO:0046427=PMID:17324931, GO:0050829=PMID:16034137, GO:0031018=PMID:18719127, GO:0006469=GO_REF:0000019, GO:0043410=PMID:12419823} P05231 Interleukin-6 protein 20110430 {GO:0032755=IDA, GO:0050830=IEP, GO:0050731=IDA, GO:0051971=IEA, GO:0005615=IDA, GO:0046888=IEA, GO:0051607=IDA, GO:0051602=IEA, GO:0045079=ISS, GO:0046677=IEA, GO:0032868=IEA, GO:0045740=IEA, GO:0042832=IEA, GO:1901215=IEA, GO:0030168=TAS, GO:0005896=IDA, GO:0006953=TAS, GO:0005125=NAS, GO:0048635=IEA, GO:0042110=IEA, GO:0032966=IDA, GO:0016049=IEA, GO:0045454=IEA, GO:0060445=IEA, GO:0001781=IDA, GO:0050710=IEA, GO:0046716=IEA, GO:0051091=IDA, GO:0006955=IEA, GO:0033138=IDA, GO:0051092=IDA, GO:0006954=IDA, GO:0002675=IDA, GO:0060664=IEA, GO:0002384=IDA, GO:0006959=IC, GO:0042102=IDA, GO:0043154=IEA, GO:0043200=IEA, GO:0045721=IEA, GO:0042493=IEA, GO:0042517=IDA, GO:0009611=IEA, GO:0005576=TAS, GO:0042981=IDA, GO:0045727=IDA, GO:0048661=IDA, GO:0002690=IC, GO:0010888=NAS, GO:0009612=IEA, GO:0045669=TAS, GO:0045666=IEA, GO:0051024=IDA, GO:0032494=IEP, GO:0033160=IEA, GO:0070301=IDA, GO:0009408=IEA, GO:0045599=NAS, GO:0008360=IEA, GO:0009409=IEA, GO:0019221=IDA, GO:0031175=IMP, GO:0046849=IEA, GO:0032496=IEA, GO:0031667=IEA, GO:0070102=IDA, GO:0070374=IEA, GO:0050679=IEA, GO:0007568=IEA, GO:0051384=IDA, GO:0032722=IDA, GO:0051592=IEA, GO:0050871=IDA, GO:0045893=IDA, GO:0008083=IDA, GO:0009897=IEA, GO:0005138=IPI, GO:0051897=IEA, GO:0008284=IMP, GO:0008285=IEA, GO:0045188=IEA, GO:0045429=IEA, GO:0031000=IEA, GO:0045944=IDA, GO:0070091=ISS, GO:0045630=IEA, GO:2000366=IC, GO:0043066=IMP, GO:0002446=IC, GO:0045765=IC, GO:0010574=IDA, GO:0002548=IC, GO:0046427=IDA, GO:0050829=IEP, GO:0031018=ISS, GO:0006469=IEA, GO:0043410=IDA} T cell activation, acute-phase response, aging, bone remodeling, branching involved in salivary gland morphogenesis, cell growth, cell redox homeostasis, cellular response to hydrogen peroxide, cytokine-mediated signaling pathway, defense response to Gram-negative bacterium, defense response to Gram-positive bacterium, defense response to protozoan, defense response to virus, endocrine pancreas development, epithelial cell proliferation involved in salivary gland morphogenesis, glucagon secretion, hepatic immune response, humoral immune response, immune response, inflammatory response, interleukin-6-mediated signaling pathway, monocyte chemotaxis, muscle cell homeostasis, negative regulation of apoptotic process, negative regulation of cell proliferation, negative regulation of chemokine biosynthetic process, negative regulation of collagen biosynthetic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of cytokine secretion, negative regulation of fat cell differentiation, negative regulation of gluconeogenesis, negative regulation of hormone secretion, negative regulation of lipid storage, negative regulation of muscle organ development, negative regulation of neuron death, negative regulation of protein kinase activity, neuron projection development, neutrophil apoptotic process, neutrophil mediated immunity, platelet activation, positive regulation of B cell activation, positive regulation of DNA replication, positive regulation of ERK1 and ERK2 cascade, positive regulation of JAK-STAT cascade, positive regulation of MAPK cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of STAT protein import into nucleus, positive regulation of T cell proliferation, positive regulation of T-helper 2 cell differentiation, positive regulation of acute inflammatory response, positive regulation of cell proliferation, positive regulation of chemokine production, positive regulation of epithelial cell proliferation, positive regulation of immunoglobulin secretion, positive regulation of interleukin-6 production, positive regulation of leukocyte chemotaxis, positive regulation of neuron differentiation, positive regulation of nitric oxide biosynthetic process, positive regulation of osteoblast differentiation, positive regulation of peptidyl-serine phosphorylation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of protein import into nucleus, translocation, positive regulation of protein kinase B signaling cascade, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of smooth muscle cell proliferation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of translation, positive regulation of transmission of nerve impulse, positive regulation of tyrosine phosphorylation of Stat3 protein, regulation of angiogenesis, regulation of apoptotic process, regulation of cell shape, regulation of circadian sleep/wake cycle, non-REM sleep, regulation of vascular endothelial growth factor production, response to amino acid stimulus, response to antibiotic, response to caffeine, response to calcium ion, response to cold, response to drug, response to electrical stimulus, response to glucocorticoid stimulus, response to heat, response to insulin stimulus, response to lipopolysaccharide, response to mechanical stimulus, response to nutrient levels, response to peptidoglycan, response to wounding external side of plasma membrane, extracellular region, extracellular space, interleukin-6 receptor complex cytokine activity, growth factor activity, interleukin-6 receptor binding Human GO:0045944 IL6R BHF-UCL UniProtKB {GO:0005138=PMID:12829785, GO:0005515=PMID:16034137, GO:0032755=PMID:10510402, GO:0008284=PMID:2261637, GO:0005886=Reactome:REACT_27288, GO:0070119=PMID:12643274, GO:0019221=PMID:2261637, GO:0019981=PMID:12829785, GO:0050731=PMID:11884403, GO:0042803=PMID:12633863, GO:0016323=GO_REF:0000039, GO:0016324=PMID:16034137, GO:0002384=PMID:12832423, GO:0004897=PMID:12643274, GO:0070102=PMID:12643274, GO:0034097=PMID:2261637, GO:0043066=PMID:18719127, GO:0004896=GO_REF:0000002, GO:0009986=GO_REF:0000019, GO:0004915=PMID:2261637, GO:0042517=PMID:12643274, GO:0005896=PMID:2261637, GO:0005576=Reactome:REACT_27309, GO:0042981=PMID:15100312, GO:0006953=PMID:12832423, GO:0032722=PMID:10510402, GO:0070120=PMID:12643274, GO:0048661=PMID:10510402, GO:0002690=PMID:15100312, GO:0002548=PMID:10510402, GO:0045669=PMID:12372336, GO:0050829=PMID:16034137, GO:0016020=GO_REF:0000002, GO:0031018=PMID:18719127, GO:0019899=PMID:12748171} P08887 Interleukin-6 receptor subunit alpha protein 20081031 {GO:0005138=IPI, GO:0005515=IPI, GO:0032755=IDA, GO:0008284=IDA, GO:0005886=TAS, GO:0070119=IPI, GO:0019221=IDA, GO:0019981=IPI, GO:0050731=IDA, GO:0042803=IPI, GO:0016323=IEA, GO:0016324=IDA, GO:0002384=TAS, GO:0004897=IMP, GO:0070102=IMP, GO:0034097=IDA, GO:0043066=IMP, GO:0004896=IEA, GO:0009986=IEA, GO:0004915=IDA, GO:0042517=IMP, GO:0005896=IDA, GO:0005576=TAS, GO:0042981=TAS, GO:0006953=TAS, GO:0032722=IDA, GO:0070120=IMP, GO:0048661=IDA, GO:0002690=TAS, GO:0002548=IC, GO:0045669=TAS, GO:0050829=IEP, GO:0016020=IEA, GO:0031018=IMP, GO:0019899=IPI} acute-phase response, ciliary neurotrophic factor-mediated signaling pathway, cytokine-mediated signaling pathway, defense response to Gram-negative bacterium, endocrine pancreas development, hepatic immune response, interleukin-6-mediated signaling pathway, monocyte chemotaxis, negative regulation of apoptotic process, positive regulation of cell proliferation, positive regulation of chemokine production, positive regulation of interleukin-6 production, positive regulation of leukocyte chemotaxis, positive regulation of osteoblast differentiation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of smooth muscle cell proliferation, positive regulation of tyrosine phosphorylation of Stat3 protein, regulation of apoptotic process, response to cytokine stimulus apical plasma membrane, basolateral plasma membrane, cell surface, extracellular region, interleukin-6 receptor complex, membrane, plasma membrane ciliary neurotrophic factor binding, ciliary neurotrophic factor receptor activity, cytokine receptor activity, enzyme binding, interleukin-6 binding, interleukin-6 receptor activity, interleukin-6 receptor binding, protein binding, protein homodimerization activity Human IL6ST GOC UniProtKB {GO:0005138=PMID:12829785, GO:0005515=PMID:10982829, GO:0004921=GO_REF:0000019, GO:0008284=PMID:2261637, GO:0005886=Reactome:REACT_27309, GO:0004924=PMID:8999038, GO:0019221=PMID:2261637, GO:0004923=PMID:12643274, GO:0019981=PMID:12829785, GO:0042803=PMID:8390097, GO:0030425=GO_REF:0000019, GO:0070110=PMID:12707266, GO:0002675=PMID:8999038, GO:0019838=PMID:8999038, GO:0042102=PMID:14764690, GO:0043025=GO_REF:0000019, GO:0070102=PMID:2261637, GO:0004897=PMID:12643274, GO:0002821=PMID:14764690, GO:0034097=PMID:2261637, GO:0010613=PMID:10744750, GO:0008593=GO_REF:0000019, GO:0070106=PMID:14764690, GO:0043066=PMID:17530315, GO:0042517=PMID:14764690, GO:0004915=PMID:12643274, GO:0005977=GO_REF:0000019, GO:0042511=PMID:14764690, GO:0005896=PMID:2261637, GO:0005576=Reactome:REACT_27205, GO:0019970=GO_REF:0000019, GO:0070120=PMID:12643274, GO:0010575=PMID:10744750, GO:0038165=PMID:8999038, GO:0005127=PMID:12707266, GO:0045669=PMID:12372336, GO:0048861=PMID:12643274, GO:0048711=GO_REF:0000019, GO:0005900=PMID:8999038, GO:0045509=PMID:14764690, GO:0009897=GO_REF:0000019} P40189 Interleukin-6 receptor subunit beta protein 20130413 {GO:0005138=IPI, GO:0005515=IPI, GO:0004921=IEA, GO:0008284=IDA, GO:0005886=TAS, GO:0004924=IDA, GO:0019221=IDA, GO:0004923=IGI, GO:0019981=IPI, GO:0042803=TAS, GO:0030425=IEA, GO:0070110=IDA, GO:0002675=IC, GO:0019838=IPI, GO:0042102=IMP, GO:0043025=IEA, GO:0070102=IDA, GO:0004897=IDA, GO:0002821=IC, GO:0034097=IDA, GO:0010613=TAS, GO:0008593=IEA, GO:0070106=IMP, GO:0043066=TAS, GO:0042517=IMP, GO:0004915=IGI, GO:0005977=IEA, GO:0042511=IMP, GO:0005896=IDA, GO:0005576=TAS, GO:0019970=IEA, GO:0070120=IDA, GO:0010575=TAS, GO:0038165=IDA, GO:0005127=IPI, GO:0045669=IMP, GO:0048861=IGI, GO:0048711=IEA, GO:0005900=IDA, GO:0045509=IC, GO:0009897=IEA} ciliary neurotrophic factor-mediated signaling pathway, cytokine-mediated signaling pathway, glycogen metabolic process, interleukin-27-mediated signaling pathway, interleukin-6-mediated signaling pathway, leukemia inhibitory factor signaling pathway, negative regulation of apoptotic process, oncostatin-M-mediated signaling pathway, positive regulation of T cell proliferation, positive regulation of acute inflammatory response, positive regulation of adaptive immune response, positive regulation of astrocyte differentiation, positive regulation of cardiac muscle hypertrophy, positive regulation of cell proliferation, positive regulation of osteoblast differentiation, positive regulation of tyrosine phosphorylation of Stat1 protein, positive regulation of tyrosine phosphorylation of Stat3 protein, positive regulation vascular endothelial growth factor production, regulation of Notch signaling pathway, response to cytokine stimulus ciliary neurotrophic factor receptor complex, dendrite, external side of plasma membrane, extracellular region, interleukin-6 receptor complex, neuronal cell body, oncostatin-M receptor complex, plasma membrane ciliary neurotrophic factor receptor activity, ciliary neurotrophic factor receptor binding, growth factor binding, interleukin-11 binding, interleukin-11 receptor activity, interleukin-27 receptor activity, interleukin-6 binding, interleukin-6 receptor activity, interleukin-6 receptor binding, leukemia inhibitory factor receptor activity, oncostatin-M receptor activity, protein binding, protein homodimerization activity Human IL7 InterPro UniProtKB {GO:0005515=PMID:8266077, GO:0010468=GO_REF:0000019, GO:0008284=PMID:2643102, GO:0043066=GO_REF:0000024, GO:0046622=GO_REF:0000019, GO:0030890=GO_REF:0000024, GO:0045453=GO_REF:0000024, GO:0007267=PMID:2643102, GO:0005576=GO_REF:0000002, GO:0005125=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0043086=GO_REF:0000019, GO:0005126=GO_REF:0000002, GO:0006955=GO_REF:0000002, GO:0048873=GO_REF:0000019, GO:0006959=PMID:2643102, GO:0009887=PMID:2643102, GO:0002360=GO_REF:0000019, GO:0005139=GO_REF:0000002, GO:0008083=GO_REF:0000002, GO:0045582=GO_REF:0000024} Q5FBY6 IL7 nirs variant 3 protein 20130413 {GO:0005515=IPI, GO:0010468=IEA, GO:0008284=TAS, GO:0043066=ISS, GO:0046622=IEA, GO:0030890=ISS, GO:0045453=ISS, GO:0007267=TAS, GO:0005576=IEA, GO:0005125=IEA, GO:0005615=IEA, GO:0043086=IEA, GO:0005126=IEA, GO:0006955=IEA, GO:0048873=IEA, GO:0006959=TAS, GO:0009887=TAS, GO:0002360=IEA, GO:0005139=IEA, GO:0008083=IEA, GO:0045582=ISS} T cell lineage commitment, bone resorption, cell-cell signaling, homeostasis of number of cells within a tissue, humoral immune response, immune response, negative regulation of apoptotic process, negative regulation of catalytic activity, organ morphogenesis, positive regulation of B cell proliferation, positive regulation of T cell differentiation, positive regulation of cell proliferation, positive regulation of organ growth, regulation of gene expression extracellular region, extracellular space cytokine activity, cytokine receptor binding, growth factor activity, interleukin-7 receptor binding, protein binding Human InterPro:IPR000226|InterPro:IPR001181 IL7R GOC UniProtKB {GO:0005515=PMID:8266077, GO:0033089=GO_REF:0000019, GO:0008361=GO_REF:0000019, GO:0005886=Reactome:REACT_115823, GO:0003823=PMID:9495344, GO:0048535=GO_REF:0000019, GO:0048872=GO_REF:0000019, GO:0006955=PMID:9843216, GO:0042100=GO_REF:0000019, GO:0038111=PMID:8266077, GO:0004896=GO_REF:0000002, GO:0004917=PMID:8266077, GO:0005576=GO_REF:0000039, GO:0010628=GO_REF:0000019, GO:0000902=GO_REF:0000019, GO:0007165=PMID:2317865, GO:0016020=GO_REF:0000002, GO:0030217=GO_REF:0000019, GO:0001915=GO_REF:0000019, GO:0016049=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0000018=PMID:9495344, GO:0009897=GO_REF:0000019, GO:0002377=GO_REF:0000019, GO:0007166=PMID:9843216} P16871 Interleukin-7 receptor subunit alpha protein 20130413 {GO:0005515=IPI, GO:0033089=IEA, GO:0008361=IEA, GO:0005886=TAS, GO:0003823=TAS, GO:0048535=IEA, GO:0048872=IEA, GO:0006955=TAS, GO:0042100=IEA, GO:0038111=TAS, GO:0004896=IEA, GO:0004917=TAS, GO:0005576=IEA, GO:0010628=IEA, GO:0000902=IEA, GO:0007165=TAS, GO:0016020=IEA, GO:0030217=IEA, GO:0001915=IEA, GO:0016049=IEA, GO:0016021=IEA, GO:0000018=TAS, GO:0009897=IEA, GO:0002377=IEA, GO:0007166=TAS} B cell proliferation, T cell differentiation, cell growth, cell morphogenesis, cell surface receptor signaling pathway, homeostasis of number of cells, immune response, immunoglobulin production, interleukin-7-mediated signaling pathway, lymph node development, negative regulation of T cell mediated cytotoxicity, positive regulation of T cell differentiation in thymus, positive regulation of gene expression, regulation of DNA recombination, regulation of cell size, signal transduction external side of plasma membrane, extracellular region, integral to membrane, membrane, plasma membrane antigen binding, cytokine receptor activity, interleukin-7 receptor activity, protein binding Human IL8 BHF-UCL UniProtKB {GO:0005515=PMID:10880251, GO:0034976=PMID:20829347, GO:0005153=PMID:1840701, GO:0019722=PMID:11877327, GO:0008285=PMID:9551928, GO:0002237=PMID:19912257, GO:0006928=PMID:10820279, GO:0030155=PMID:2007144, GO:0005615=GO_REF:0000037, GO:0030968=Reactome:REACT_18356, GO:0045091=PMID:11483765, GO:0035556=PMID:10734056, GO:0006955=GO_REF:0000002, GO:0006954=PMID:11483765, GO:0071356=GO_REF:0000002, GO:0007050=PMID:11564821, GO:0008009=GO_REF:0000002, GO:0045744=PMID:10734056, GO:0030593=PMID:11564821, GO:0005576=Reactome:REACT_115727, GO:0048566=PMID:20875417, GO:0001525=PMID:11483765, GO:0050930=PMID:11564821, GO:0007165=PMID:10820279, GO:0071222=PMID:19912257, GO:0007186=PMID:8381837, GO:0071347=GO_REF:0000002, GO:0090023=PMID:1699135, GO:0042119=PMID:11483765, GO:0006987=Reactome:REACT_18277, GO:0044267=Reactome:REACT_17015} P10145 Interleukin-8 protein 20110202 {GO:0005515=IPI, GO:0034976=IDA, GO:0005153=IPI, GO:0019722=TAS, GO:0008285=TAS, GO:0002237=IDA, GO:0006928=TAS, GO:0030155=IDA, GO:0005615=IEA, GO:0030968=TAS, GO:0045091=IDA, GO:0035556=IDA, GO:0006955=IEA, GO:0006954=TAS, GO:0071356=IEA, GO:0007050=IDA, GO:0008009=IEA, GO:0045744=IDA, GO:0030593=IGI, GO:0005576=TAS, GO:0048566=IEP, GO:0001525=TAS, GO:0050930=IGI, GO:0007165=TAS, GO:0071222=IDA, GO:0007186=TAS, GO:0071347=IEA, GO:0090023=TAS, GO:0042119=TAS, GO:0006987=TAS, GO:0044267=TAS} G-protein coupled receptor signaling pathway, activation of signaling protein activity involved in unfolded protein response, angiogenesis, calcium-mediated signaling, cell cycle arrest, cellular component movement, cellular protein metabolic process, cellular response to interleukin-1, cellular response to lipopolysaccharide, cellular response to tumor necrosis factor, embryonic digestive tract development, endoplasmic reticulum unfolded protein response, immune response, induction of positive chemotaxis, inflammatory response, intracellular signal transduction, negative regulation of G-protein coupled receptor protein signaling pathway, negative regulation of cell proliferation, neutrophil activation, neutrophil chemotaxis, positive regulation of neutrophil chemotaxis, regulation of cell adhesion, regulation of retroviral genome replication, response to endoplasmic reticulum stress, response to molecule of bacterial origin, signal transduction extracellular region, extracellular space chemokine activity, interleukin-8 receptor binding, protein binding Human IL9 PINC UniProtKB {GO:0008284=PMID:1680606, GO:0006955=GO_REF:0000002, GO:0006954=PMID:9371819, GO:0030307=GO_REF:0000019, GO:0045407=GO_REF:0000024, GO:0005140=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0005125=GO_REF:0000019, GO:0008083=GO_REF:0000037} P15248 Interleukin-9 protein 20030904 {GO:0008284=TAS, GO:0006955=IEA, GO:0006954=TAS, GO:0030307=IEA, GO:0045407=ISS, GO:0005140=IEA, GO:0005615=IEA, GO:0005125=IEA, GO:0008083=IEA} immune response, inflammatory response, positive regulation of cell growth, positive regulation of cell proliferation, positive regulation of interleukin-5 biosynthetic process extracellular space cytokine activity, growth factor activity, interleukin-9 receptor binding Human IL9R GOC UniProtKB {GO:0007165=PMID:1376929, GO:0004896=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0008283=PMID:1376929, GO:0005887=PMID:1376929, GO:0004919=PMID:1376929, GO:0005615=PMID:1376929, GO:0038113=PMID:1376929} Q01113 Interleukin-9 receptor protein 20130413 {GO:0007165=TAS, GO:0004896=IEA, GO:0016020=IEA, GO:0008283=TAS, GO:0005887=TAS, GO:0004919=TAS, GO:0005615=TAS, GO:0038113=TAS} cell proliferation, interleukin-9-mediated signaling pathway, signal transduction extracellular space, integral to plasma membrane, membrane cytokine receptor activity, interleukin-9 receptor activity Human ILDR2 ENSEMBL UniProtKB {GO:0048873=GO_REF:0000019, GO:0031016=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0030073=GO_REF:0000019, GO:0030154=GO_REF:0000019, GO:0009749=GO_REF:0000019} Q71H61 Immunoglobulin-like domain-containing receptor 2 protein 20130413 {GO:0048873=IEA, GO:0031016=IEA, GO:0016021=IEA, GO:0030073=IEA, GO:0030154=IEA, GO:0009749=IEA} cell differentiation, homeostasis of number of cells within a tissue, insulin secretion, pancreas development, response to glucose stimulus integral to membrane Human Ensembl:ENSMUSP00000107047 ILF2 HPA UniProtKB {GO:0003725=PMID:10574923, GO:0005515=PMID:21146485, GO:0005737=GO_REF:0000039, GO:0006955=GO_REF:0000002, GO:0030529=PMID:17289661, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0045893=PMID:11739746, GO:0003677=PMID:11804788, GO:0005524=GO_REF:0000002, GO:0006351=PMID:11739746, GO:0016740=GO_REF:0000002} Q12905 Interleukin enhancer-binding factor 2 protein 20101115 {GO:0003725=IDA, GO:0005515=IPI, GO:0005737=IEA, GO:0006955=IEA, GO:0030529=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0045893=IDA, GO:0003677=IDA, GO:0005524=IEA, GO:0006351=IDA, GO:0016740=IEA} immune response, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleolus, nucleus, ribonucleoprotein complex ATP binding, DNA binding, double-stranded RNA binding, protein binding, transferase activity NOT Human ILF3 HPA UniProtKB {GO:0005515=PMID:10749851, GO:0005739=GO_REF:0000052, GO:0003725=PMID:10574923, GO:0030529=PMID:17289661, GO:0003723=PMID:10400669, GO:0005730=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0045893=PMID:11739746, GO:0045892=PMID:11739746, GO:0003677=PMID:10574923, GO:0006351=GO_REF:0000037, GO:0000279=PMID:8885239} Q12906 Interleukin enhancer-binding factor 3 protein 20080205 {GO:0005515=IPI, GO:0005739=IDA, GO:0003725=IDA, GO:0030529=IDA, GO:0003723=NAS, GO:0005730=IEA, GO:0005634=IDA, GO:0045893=IDA, GO:0045892=IDA, GO:0003677=IDA, GO:0006351=IEA, GO:0000279=NAS} M phase, negative regulation of transcription, DNA-dependent, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent mitochondrion, nucleolus, nucleus, ribonucleoprotein complex DNA binding, RNA binding, double-stranded RNA binding, protein binding Human ILK IntAct UniProtKB {GO:0005515=PMID:23455922, GO:0001658=GO_REF:0000019, GO:0090263=PMID:20018240, GO:0030017=GO_REF:0000039, GO:0043524=GO_REF:0000019, GO:0018105=GO_REF:0000019, GO:0032956=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0034446=PMID:19118217, GO:0010667=GO_REF:0000019, GO:0030335=GO_REF:0000019, GO:0019901=PMID:19118217, GO:0034329=Reactome:REACT_20676, GO:0007569=GO_REF:0000019, GO:0030027=GO_REF:0000039, GO:0045197=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0005178=GO_REF:0000019, GO:0007229=PMID:9366252, GO:0050775=GO_REF:0000019, GO:0043034=GO_REF:0000019, GO:0045893=PMID:20018240, GO:0005925=GO_REF:0000039, GO:0001954=GO_REF:0000019, GO:0051897=GO_REF:0000019, GO:0017124=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0008283=PMID:10871859, GO:0045773=GO_REF:0000019, GO:0051291=GO_REF:0000019, GO:0014912=GO_REF:0000019, GO:0005829=Reactome:REACT_20656, GO:0030513=GO_REF:0000019, GO:0005737=GO_REF:0000029, GO:0005911=GO_REF:0000019, GO:0043198=GO_REF:0000019, GO:0043406=GO_REF:0000019, GO:0043195=GO_REF:0000019, GO:0007050=GO_REF:0000019, GO:0004871=GO_REF:0000019, GO:0043206=GO_REF:0000019, GO:0048662=GO_REF:0000019, GO:0005524=GO_REF:0000029, GO:0032288=GO_REF:0000019, GO:0045669=GO_REF:0000019, GO:0004672=GO_REF:0000002, GO:0007160=GO_REF:0000029, GO:0004674=PMID:9366252, GO:0045663=GO_REF:0000019, GO:0048812=GO_REF:0000019, GO:0006468=PMID:10871859, GO:0006469=GO_REF:0000019, GO:0042327=PMID:20018240} Q13418 Integrin-linked protein kinase protein 20130415 {GO:0005515=IPI, GO:0001658=IEA, GO:0090263=IMP, GO:0030017=IEA, GO:0043524=IEA, GO:0018105=IEA, GO:0032956=IEA, GO:0043025=IEA, GO:0034446=IMP, GO:0010667=IEA, GO:0030335=IEA, GO:0019901=IPI, GO:0034329=TAS, GO:0007569=IEA, GO:0030027=IEA, GO:0045197=IEA, GO:0043234=IEA, GO:0005178=IEA, GO:0007229=IDA, GO:0050775=IEA, GO:0043034=IEA, GO:0045893=IMP, GO:0005925=IEA, GO:0001954=IEA, GO:0051897=IEA, GO:0017124=IEA, GO:0008284=IEA, GO:0005886=IEA, GO:0008283=NAS, GO:0045773=IEA, GO:0051291=IEA, GO:0014912=IEA, GO:0005829=TAS, GO:0030513=IEA, GO:0005737=NAS, GO:0005911=IEA, GO:0043198=IEA, GO:0043406=IEA, GO:0043195=IEA, GO:0007050=IEA, GO:0004871=IEA, GO:0043206=IEA, GO:0048662=IEA, GO:0005524=NAS, GO:0032288=IEA, GO:0045669=IEA, GO:0004672=IEA, GO:0007160=NAS, GO:0004674=IDA, GO:0045663=IEA, GO:0048812=IEA, GO:0006468=IDA, GO:0006469=IEA, GO:0042327=IMP} branching involved in ureteric bud morphogenesis, cell aging, cell cycle arrest, cell junction assembly, cell proliferation, cell-matrix adhesion, establishment or maintenance of epithelial cell apical/basal polarity, extracellular fibril organization, integrin-mediated signaling pathway, myelin assembly, negative regulation of cardiac muscle cell apoptotic process, negative regulation of neuron apoptotic process, negative regulation of protein kinase activity, negative regulation of smooth muscle cell migration, negative regulation of smooth muscle cell proliferation, neuron projection morphogenesis, peptidyl-serine phosphorylation, positive regulation of BMP signaling pathway, positive regulation of MAP kinase activity, positive regulation of axon extension, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of cell-matrix adhesion, positive regulation of dendrite morphogenesis, positive regulation of myoblast differentiation, positive regulation of osteoblast differentiation, positive regulation of phosphorylation, positive regulation of protein kinase B signaling cascade, positive regulation of transcription, DNA-dependent, protein heterooligomerization, protein phosphorylation, regulation of actin cytoskeleton organization, substrate adhesion-dependent cell spreading cell-cell junction, costamere, cytoplasm, cytosol, dendritic shaft, focal adhesion, lamellipodium, neuronal cell body, plasma membrane, protein complex, sarcomere, terminal bouton ATP binding, SH3 domain binding, integrin binding, protein binding, protein kinase activity, protein kinase binding, protein serine/threonine kinase activity, signal transducer activity Human UniProtKB:Q9NVD7 ILKAP IntAct UniProtKB {GO:0005515=PMID:11331582, GO:0005737=GO_REF:0000039, GO:0006470=GO_REF:0000019, GO:0004722=GO_REF:0000019, GO:0045786=GO_REF:0000019, GO:0007090=GO_REF:0000019, GO:0003824=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q9H0C8 Integrin-linked kinase-associated serine/threonine phosphatase 2C protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0006470=IEA, GO:0004722=IEA, GO:0045786=IEA, GO:0007090=IEA, GO:0003824=IEA, GO:0046872=IEA} negative regulation of cell cycle, protein dephosphorylation, regulation of S phase of mitotic cell cycle cytoplasm catalytic activity, metal ion binding, protein binding, protein serine/threonine phosphatase activity Human UniProtKB:Q13418 ILVBL InterPro UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0000287=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037, GO:0003824=GO_REF:0000002, GO:0030976=GO_REF:0000002, GO:0016740=GO_REF:0000037} M0R1B5 Acetolactate synthase-like protein protein 20130413 {GO:0008150=ND, GO:0003674=ND, GO:0000287=IEA, GO:0005575=ND, GO:0016021=IEA, GO:0003824=IEA, GO:0030976=IEA, GO:0016740=IEA} biological_process cellular_component, integral to membrane catalytic activity, magnesium ion binding, molecular_function, thiamine pyrophosphate binding, transferase activity Human InterPro:IPR012001 IMMT IntAct UniProtKB {GO:0005515=PMID:16169070, GO:0008150=GO_REF:0000015, GO:0051560=GO_REF:0000019, GO:0009409=GO_REF:0000019, GO:0005743=PMID:9168817, GO:0016021=GO_REF:0000037} Q16891 Mitochondrial inner membrane protein protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0051560=IEA, GO:0009409=IEA, GO:0005743=IDA, GO:0016021=IEA} biological_process, mitochondrial calcium ion homeostasis, response to cold integral to membrane, mitochondrial inner membrane protein binding Human UniProtKB:O60341 IMP3 LIFEdb UniProtKB {GO:0005515=PMID:12655004, GO:0030529=GO_REF:0000037, GO:0006364=GO_REF:0000037, GO:0005730=PMID:12655004, GO:0005634=GO_REF:0000054, GO:0019843=GO_REF:0000037} Q9NV31 U3 small nucleolar ribonucleoprotein protein IMP3 protein 20100607 {GO:0005515=IPI, GO:0030529=IEA, GO:0006364=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0019843=IEA} rRNA processing nucleolus, nucleus, ribonucleoprotein complex protein binding, rRNA binding Human IMP4 HGNC UniProtKB {GO:0005515=PMID:12655004, GO:0006364=PMID:12655004, GO:0030529=GO_REF:0000037, GO:0005730=PMID:12655004} Q96G21 U3 small nucleolar ribonucleoprotein protein IMP4 protein 20050221 {GO:0005515=IPI, GO:0006364=NAS, GO:0030529=IEA, GO:0005730=IDA} rRNA processing nucleolus, ribonucleoprotein complex protein binding Human IMPA1 HPA UniProtKB {GO:0052833=GO_REF:0000003, GO:0052832=GO_REF:0000003, GO:0006021=GO_REF:0000041, GO:0043647=Reactome:REACT_150352, GO:0006661=PMID:1377913, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0006796=PMID:1377913, GO:0042803=PMID:17068342, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_150231, GO:0005739=GO_REF:0000052, GO:0046854=GO_REF:0000002, GO:0007165=PMID:1377913, GO:0005737=PMID:17068342, GO:0046855=PMID:17068342, GO:0008934=PMID:17068342} P29218 Inositol monophosphatase 1 protein 20110516 {GO:0052833=IEA, GO:0052832=IEA, GO:0006021=IEA, GO:0043647=TAS, GO:0006661=IMP, GO:0005730=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0006796=IMP, GO:0042803=IPI, GO:0046872=IEA, GO:0005829=TAS, GO:0005739=IDA, GO:0046854=IEA, GO:0007165=IMP, GO:0005737=IDA, GO:0046855=IDA, GO:0008934=IDA} inositol biosynthetic process, inositol phosphate dephosphorylation, inositol phosphate metabolic process, phosphate-containing compound metabolic process, phosphatidylinositol biosynthetic process, phosphatidylinositol phosphorylation, signal transduction, small molecule metabolic process cytoplasm, cytosol, mitochondrion, nucleolus, nucleus inositol monophosphate 1-phosphatase activity, inositol monophosphate 3-phosphatase activity, inositol monophosphate 4-phosphatase activity, metal ion binding, protein homodimerization activity Human IMPA2 InterPro UniProtKB {GO:0052833=GO_REF:0000003, GO:0052832=GO_REF:0000003, GO:0006021=GO_REF:0000041, GO:0043647=Reactome:REACT_150352, GO:0044281=Reactome:REACT_111217, GO:0006796=PMID:9322233, GO:0046872=GO_REF:0000037, GO:0042803=PMID:17068342, GO:0005829=Reactome:REACT_150231, GO:0046854=GO_REF:0000002, GO:0007165=PMID:9322233, GO:0005737=PMID:17068342, GO:0046855=PMID:17068342, GO:0008934=PMID:17068342} Q6PIP6 IMPA2 protein protein 20130413 {GO:0052833=IEA, GO:0052832=IEA, GO:0006021=IEA, GO:0043647=TAS, GO:0044281=TAS, GO:0006796=TAS, GO:0046872=IEA, GO:0042803=IPI, GO:0005829=TAS, GO:0046854=IEA, GO:0007165=TAS, GO:0005737=IDA, GO:0046855=IDA, GO:0008934=IDA} inositol biosynthetic process, inositol phosphate dephosphorylation, inositol phosphate metabolic process, phosphate-containing compound metabolic process, phosphatidylinositol phosphorylation, signal transduction, small molecule metabolic process cytoplasm, cytosol inositol monophosphate 1-phosphatase activity, inositol monophosphate 3-phosphatase activity, inositol monophosphate 4-phosphatase activity, metal ion binding, protein homodimerization activity Human InterPro:IPR000760 IMPACT UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0006446=GO_REF:0000019, GO:0001933=GO_REF:0000019, GO:0005575=GO_REF:0000015} Q9P2X3 Protein IMPACT protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0006446=IEA, GO:0001933=IEA, GO:0005575=ND} biological_process, negative regulation of protein phosphorylation, regulation of translational initiation cellular_component molecular_function Human IMPAD1 MGI UniProtKB {GO:0052833=GO_REF:0000003, GO:0052832=GO_REF:0000003, GO:0005794=PMID:18695242, GO:0006021=GO_REF:0000041, GO:0008441=GO_REF:0000003, GO:0009791=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0046854=GO_REF:0000002, GO:0001958=GO_REF:0000019, GO:0002063=GO_REF:0000019, GO:0008254=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0030204=GO_REF:0000019, GO:0008934=GO_REF:0000003, GO:0042733=GO_REF:0000019} Q9NX62 Inositol monophosphatase 3 protein 20091016 {GO:0052833=IEA, GO:0052832=IEA, GO:0005794=IDA, GO:0006021=IEA, GO:0008441=IEA, GO:0009791=IEA, GO:0046872=IEA, GO:0046854=IEA, GO:0001958=IEA, GO:0002063=IEA, GO:0008254=IEA, GO:0016021=IEA, GO:0030204=IEA, GO:0008934=IEA, GO:0042733=IEA} chondrocyte development, chondroitin sulfate metabolic process, embryonic digit morphogenesis, endochondral ossification, inositol biosynthetic process, phosphatidylinositol phosphorylation, post-embryonic development Golgi apparatus, integral to membrane 3'(2'),5'-bisphosphate nucleotidase activity, 3'-nucleotidase activity, inositol monophosphate 1-phosphatase activity, inositol monophosphate 3-phosphatase activity, inositol monophosphate 4-phosphatase activity, metal ion binding Human IMPDH1 Reactome UniProtKB {GO:0009168=Reactome:REACT_1776, GO:0060041=GO_REF:0000019, GO:0003938=GO_REF:0000003, GO:0003723=GO_REF:0000037, GO:0009409=GO_REF:0000019, GO:0055086=Reactome:REACT_1698, GO:0005634=PMID:14766016, GO:0044281=Reactome:REACT_111217, GO:0003676=PMID:14766016, GO:0003677=PMID:14766016, GO:0046872=GO_REF:0000020, GO:0005829=Reactome:REACT_1488, GO:0005737=PMID:14766016, GO:0006177=GO_REF:0000020, GO:0000166=GO_REF:0000020, GO:0006144=Reactome:REACT_522, GO:0046651=GO_REF:0000019, GO:0006164=GO_REF:0000002} P20839 Inosine-5'-monophosphate dehydrogenase 1 protein 20130213 {GO:0009168=TAS, GO:0060041=IEA, GO:0003938=IEA, GO:0003723=IEA, GO:0009409=IEA, GO:0055086=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0003676=IDA, GO:0003677=IDA, GO:0046872=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0006177=IEA, GO:0000166=IEA, GO:0006144=TAS, GO:0046651=IEA, GO:0006164=IEA} GMP biosynthetic process, lymphocyte proliferation, nucleobase-containing small molecule metabolic process, purine nucleobase metabolic process, purine nucleotide biosynthetic process, purine ribonucleoside monophosphate biosynthetic process, response to cold, retina development in camera-type eye, small molecule metabolic process cytoplasm, cytosol, nucleus DNA binding, IMP dehydrogenase activity, RNA binding, metal ion binding, nucleic acid binding, nucleotide binding Human IMPDH2 Reactome UniProtKB {GO:0009168=Reactome:REACT_1776, GO:0060041=GO_REF:0000019, GO:0003938=GO_REF:0000003, GO:0003723=GO_REF:0000037, GO:0055086=Reactome:REACT_1698, GO:0005634=PMID:14766016, GO:0044281=Reactome:REACT_111217, GO:0003677=GO_REF:0000037, GO:0046872=GO_REF:0000020, GO:0005829=Reactome:REACT_1488, GO:0005737=PMID:14766016, GO:0006177=GO_REF:0000020, GO:0000166=PMID:14766016, GO:0006144=Reactome:REACT_522, GO:0051289=GO_REF:0000019, GO:0046651=GO_REF:0000019, GO:0005778=PMID:21525035, GO:0006164=GO_REF:0000002} P12268 Inosine-5'-monophosphate dehydrogenase 2 protein 20130213 {GO:0009168=TAS, GO:0060041=IEA, GO:0003938=IEA, GO:0003723=IEA, GO:0055086=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0003677=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0006177=IEA, GO:0000166=IDA, GO:0006144=TAS, GO:0051289=IEA, GO:0046651=IEA, GO:0005778=IDA, GO:0006164=IEA} GMP biosynthetic process, lymphocyte proliferation, nucleobase-containing small molecule metabolic process, protein homotetramerization, purine nucleobase metabolic process, purine nucleotide biosynthetic process, purine ribonucleoside monophosphate biosynthetic process, retina development in camera-type eye, small molecule metabolic process cytoplasm, cytosol, nucleus, peroxisomal membrane DNA binding, IMP dehydrogenase activity, RNA binding, metal ion binding, nucleotide binding Human INA PINC UniProtKB {GO:0060052=GO_REF:0000019, GO:0005883=GO_REF:0000019, GO:0005200=PMID:7769995, GO:0030154=GO_REF:0000037, GO:0007399=GO_REF:0000037} Q16352 Alpha-internexin protein 20030904 {GO:0060052=IEA, GO:0005883=IEA, GO:0005200=TAS, GO:0030154=IEA, GO:0007399=IEA} cell differentiation, nervous system development, neurofilament cytoskeleton organization neurofilament structural constituent of cytoskeleton Human INADL IntAct UniProtKB {GO:0005515=PMID:21481793, GO:0035556=PMID:9280290, GO:0048471=PMID:18596123, GO:0016324=GO_REF:0000039, GO:0070830=Reactome:REACT_19373, GO:0005886=Reactome:REACT_19144, GO:0034329=Reactome:REACT_20676, GO:0005923=PMID:22006950, GO:0045216=Reactome:REACT_19331} Q8NI35 InaD-like protein protein 20130415 {GO:0005515=IPI, GO:0035556=NAS, GO:0048471=IDA, GO:0016324=IEA, GO:0070830=TAS, GO:0005886=TAS, GO:0034329=TAS, GO:0005923=IDA, GO:0045216=TAS} cell junction assembly, cell-cell junction organization, intracellular signal transduction, tight junction assembly apical plasma membrane, perinuclear region of cytoplasm, plasma membrane, tight junction protein binding Human UniProtKB:P35240 INCA1 HPA UniProtKB {GO:0005515=PMID:21874239, GO:0005737=GO_REF:0000052, GO:0045736=PMID:21540187, GO:0030332=PMID:21540187, GO:0005730=GO_REF:0000052, GO:0004861=PMID:21540187, GO:0005634=GO_REF:0000052} Q0VD86 Protein INCA1 protein 20111111 {GO:0005515=IPI, GO:0005737=IDA, GO:0045736=IDA, GO:0030332=IDA, GO:0005730=IDA, GO:0004861=IDA, GO:0005634=IDA} negative regulation of cyclin-dependent protein serine/threonine kinase activity cytoplasm, nucleolus, nucleus cyclin binding, cyclin-dependent protein serine/threonine kinase inhibitor activity, protein binding Human INCENP IntAct UniProtKB {GO:0005515=PMID:20562864, GO:0000236=Reactome:REACT_682, GO:0010369=GO_REF:0000019, GO:0005874=GO_REF:0000037, GO:0005819=PMID:9864353, GO:0030496=GO_REF:0000019, GO:0000801=GO_REF:0000019, GO:0000800=GO_REF:0000019, GO:0005829=Reactome:REACT_150414, GO:0000910=PMID:16239925, GO:0043234=PMID:16239925, GO:0007059=PMID:16239925, GO:0005721=PMID:9864353, GO:0000087=Reactome:REACT_910, GO:0000777=GO_REF:0000039, GO:0000776=PMID:16760428, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0000775=PMID:11084331} Q9NQS7 Inner centromere protein protein 20130415 {GO:0005515=IPI, GO:0000236=TAS, GO:0010369=IEA, GO:0005874=IEA, GO:0005819=IDA, GO:0030496=IEA, GO:0000801=IEA, GO:0000800=IEA, GO:0005829=TAS, GO:0000910=IMP, GO:0043234=IDA, GO:0007059=IMP, GO:0005721=IDA, GO:0000087=TAS, GO:0000777=IEA, GO:0000776=IDA, GO:0000278=TAS, GO:0000090=TAS, GO:0000775=IDA} M phase of mitotic cell cycle, chromosome segregation, cytokinesis, mitotic anaphase, mitotic cell cycle, mitotic prometaphase central element, centromeric heterochromatin, chromocenter, chromosome, centromeric region, condensed chromosome kinetochore, cytosol, kinetochore, lateral element, microtubule, midbody, protein complex, spindle protein binding Human UniProtKB:Q96GD4 INF2 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0048471=PMID:20023659, GO:0030036=GO_REF:0000002, GO:0005783=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0017048=GO_REF:0000002, GO:0003779=GO_REF:0000037} Q27J81 Inverted formin-2 protein 20101115 {GO:0005737=IDA, GO:0048471=IDA, GO:0030036=IEA, GO:0005783=IDA, GO:0005634=IDA, GO:0017048=IEA, GO:0003779=IEA} actin cytoskeleton organization cytoplasm, endoplasmic reticulum, nucleus, perinuclear region of cytoplasm Rho GTPase binding, actin binding Human ING1 PINC UniProtKB {GO:0030308=PMID:8944021, GO:0007049=GO_REF:0000037, GO:0008285=PMID:8944021, GO:0005634=PMID:10866301, GO:0008270=GO_REF:0000002, GO:0035064=PMID:16728974, GO:0006606=GO_REF:0000019, GO:0045893=GO_REF:0000019, GO:0010941=GO_REF:0000019} Q9UK53 Inhibitor of growth protein 1 protein 20050308 {GO:0030308=NAS, GO:0007049=IEA, GO:0008285=TAS, GO:0005634=NAS, GO:0008270=IEA, GO:0035064=IDA, GO:0006606=IEA, GO:0045893=IEA, GO:0010941=IEA} cell cycle, negative regulation of cell growth, negative regulation of cell proliferation, positive regulation of transcription, DNA-dependent, protein import into nucleus, regulation of cell death nucleus methylated histone residue binding, zinc ion binding Human ING2 HPA UniProtKB {GO:0005515=PMID:18334480, GO:2001020=PMID:21124965, GO:0007286=PMID:21124965, GO:0005634=GO_REF:0000052, GO:0007283=PMID:21124965, GO:0035064=PMID:16728974, GO:0032403=PMID:18334480, GO:0016580=PMID:16387653, GO:2000772=PMID:21124965, GO:0030511=PMID:18334480, GO:0006355=PMID:15243141, GO:0043066=PMID:21124965, GO:0005730=GO_REF:0000052, GO:0030317=PMID:21124965, GO:0048133=PMID:21124965, GO:0003677=PMID:15243141, GO:0006351=GO_REF:0000037, GO:0007165=PMID:10072587, GO:0016602=PMID:15243141, GO:0003682=PMID:10072587, GO:0072520=PMID:21124965, GO:0008270=GO_REF:0000002, GO:0045893=PMID:18334480, GO:0035091=PMID:16893883, GO:0007141=PMID:21124965, GO:0040008=GO_REF:0000037, GO:0016568=PMID:21124965} Q9H160 Inhibitor of growth protein 2 protein 20100326 {GO:0005515=IPI, GO:2001020=NAS, GO:0007286=ISS, GO:0005634=IDA, GO:0007283=ISS, GO:0035064=IDA, GO:0032403=IDA, GO:0016580=IDA, GO:2000772=NAS, GO:0030511=IDA, GO:0006355=IDA, GO:0043066=ISS, GO:0005730=IDA, GO:0030317=ISS, GO:0048133=ISS, GO:0003677=IDA, GO:0006351=IEA, GO:0007165=TAS, GO:0016602=IDA, GO:0003682=TAS, GO:0072520=ISS, GO:0008270=IEA, GO:0045893=IDA, GO:0035091=IDA, GO:0007141=ISS, GO:0040008=IEA, GO:0016568=ISS} chromatin modification, male germ-line stem cell division, male meiosis I, negative regulation of apoptotic process, positive regulation of transcription, DNA-dependent, positive regulation of transforming growth factor beta receptor signaling pathway, regulation of cellular senescence, regulation of growth, regulation of response to DNA damage stimulus, regulation of transcription, DNA-dependent, seminiferous tubule development, signal transduction, sperm motility, spermatid development, spermatogenesis, transcription, DNA-dependent CCAAT-binding factor complex, Sin3 complex, nucleolus, nucleus DNA binding, chromatin binding, methylated histone residue binding, phosphatidylinositol binding, protein binding, protein complex binding, zinc ion binding NOT Human ING3 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0043065=PMID:16387653, GO:0032777=PMID:14966270, GO:0043967=PMID:14966270, GO:0043968=PMID:14966270, GO:0035267=PMID:16387653, GO:0008270=GO_REF:0000002, GO:0035064=PMID:16728974, GO:0004402=PMID:14966270, GO:0040008=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9NXR8 Inhibitor of growth protein 3 protein 20110726 {GO:0006355=IEA, GO:0043065=IDA, GO:0032777=IDA, GO:0043967=IDA, GO:0043968=IDA, GO:0035267=IDA, GO:0008270=IEA, GO:0035064=IDA, GO:0004402=IDA, GO:0040008=IEA, GO:0006351=IEA} histone H2A acetylation, histone H4 acetylation, positive regulation of apoptotic process, regulation of growth, regulation of transcription, DNA-dependent, transcription, DNA-dependent NuA4 histone acetyltransferase complex, Piccolo NuA4 histone acetyltransferase complex histone acetyltransferase activity, methylated histone residue binding, zinc ion binding Human ING4 UniProtKB UniProtKB {GO:0005515=PMID:15029197, GO:0008285=PMID:15251430, GO:0043065=PMID:16387653, GO:0003713=PMID:16387653, GO:0006915=PMID:15251430, GO:0005634=PMID:15029197, GO:0035064=PMID:16728974, GO:0006260=PMID:16387653, GO:0043981=PMID:16387653, GO:0043983=PMID:16387653, GO:0043982=PMID:16387653, GO:0043966=PMID:16387653, GO:0043984=PMID:16387653, GO:0000123=PMID:16387653, GO:0008270=GO_REF:0000002, GO:0007050=PMID:15251430, GO:0006978=PMID:16387653, GO:0045892=PMID:15029197, GO:0006473=PMID:12750254, GO:0045926=PMID:12750254} Q9UNL4 Inhibitor of growth protein 4 protein 20110726 {GO:0005515=IPI, GO:0008285=IDA, GO:0043065=IDA, GO:0003713=IDA, GO:0006915=IDA, GO:0005634=IDA, GO:0035064=IDA, GO:0006260=IDA, GO:0043981=IDA, GO:0043983=IDA, GO:0043982=IDA, GO:0043966=IDA, GO:0043984=IDA, GO:0000123=IDA, GO:0008270=IEA, GO:0007050=IDA, GO:0006978=IDA, GO:0045892=IDA, GO:0006473=IDA, GO:0045926=IDA} DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, DNA replication, apoptotic process, cell cycle arrest, histone H3 acetylation, histone H4-K12 acetylation, histone H4-K16 acetylation, histone H4-K5 acetylation, histone H4-K8 acetylation, negative regulation of cell proliferation, negative regulation of growth, negative regulation of transcription, DNA-dependent, positive regulation of apoptotic process, protein acetylation histone acetyltransferase complex, nucleus methylated histone residue binding, protein binding, transcription coactivator activity, zinc ion binding Human ING5 MGI UniProtKB {GO:0005515=PMID:12750254, GO:0070776=PMID:18794358, GO:0008285=PMID:21750715, GO:0043065=PMID:21750715, GO:0005634=PMID:18794358, GO:0035064=PMID:16728974, GO:0045749=PMID:21750715, GO:0006351=GO_REF:0000037, GO:0006260=PMID:16387653, GO:0043966=PMID:16387653, GO:0008270=GO_REF:0000002, GO:0045893=PMID:16387653, GO:0006473=PMID:12750254, GO:0045926=PMID:12750254} Q8WYH8 Inhibitor of growth protein 5 protein 20130107 {GO:0005515=IPI, GO:0070776=IDA, GO:0008285=IGI, GO:0043065=IGI, GO:0005634=IDA, GO:0035064=IDA, GO:0045749=IDA, GO:0006351=IEA, GO:0006260=IDA, GO:0043966=IDA, GO:0008270=IEA, GO:0045893=IDA, GO:0006473=IDA, GO:0045926=IDA} DNA replication, histone H3 acetylation, negative regulation of S phase of mitotic cell cycle, negative regulation of cell proliferation, negative regulation of growth, positive regulation of apoptotic process, positive regulation of transcription, DNA-dependent, protein acetylation, transcription, DNA-dependent MOZ/MORF histone acetyltransferase complex, nucleus methylated histone residue binding, protein binding, zinc ion binding Human INHA BHF-UCL UniProtKB {GO:0045578=PMID:12456957, GO:0042541=PMID:1310063, GO:0005515=PMID:10746731, GO:0007267=PMID:12456957, GO:0034673=PMID:10746731, GO:0030154=PMID:12456957, GO:0001541=PMID:9166111, GO:0045077=PMID:12456957, GO:0042127=PMID:9032295, GO:0051726=PMID:9032295, GO:0043025=GO_REF:0000019, GO:0007050=PMID:12456957, GO:0046982=GO_REF:0000019, GO:0005102=PMID:9032295, GO:0046882=PMID:3267209, GO:0046881=PMID:12456957, GO:0005576=PMID:12456957, GO:0006917=PMID:8267637, GO:0045786=PMID:12456957, GO:0045650=PMID:12456957, GO:0005125=PMID:12456957, GO:0007399=PMID:10320815, GO:0042326=PMID:12456957, GO:0007165=PMID:3267209, GO:0001917=GO_REF:0000019, GO:0001501=PMID:10865214, GO:0009605=PMID:10320815, GO:0005179=PMID:12456957, GO:0034711=GO_REF:0000019, GO:0043512=PMID:7890768, GO:0030218=PMID:1310063, GO:0008083=PMID:12324653, GO:0007166=PMID:12456957, GO:0008584=GO_REF:0000019, GO:0001750=GO_REF:0000019} P05111 Inhibin alpha chain protein 20080909 {GO:0045578=TAS, GO:0042541=IDA, GO:0005515=IPI, GO:0007267=TAS, GO:0034673=IDA, GO:0030154=TAS, GO:0001541=NAS, GO:0045077=TAS, GO:0042127=IDA, GO:0051726=IDA, GO:0043025=IEA, GO:0007050=TAS, GO:0046982=IEA, GO:0005102=IPI, GO:0046882=NAS, GO:0046881=TAS, GO:0005576=TAS, GO:0006917=IDA, GO:0045786=TAS, GO:0045650=TAS, GO:0005125=TAS, GO:0007399=NAS, GO:0042326=TAS, GO:0007165=TAS, GO:0001917=IEA, GO:0001501=TAS, GO:0009605=TAS, GO:0005179=TAS, GO:0034711=IEA, GO:0043512=IDA, GO:0030218=NAS, GO:0008083=TAS, GO:0007166=TAS, GO:0008584=IEA, GO:0001750=IEA} cell cycle arrest, cell differentiation, cell surface receptor signaling pathway, cell-cell signaling, erythrocyte differentiation, hemoglobin biosynthetic process, induction of apoptosis, male gonad development, negative regulation of B cell differentiation, negative regulation of cell cycle, negative regulation of follicle-stimulating hormone secretion, negative regulation of interferon-gamma biosynthetic process, negative regulation of macrophage differentiation, negative regulation of phosphorylation, nervous system development, ovarian follicle development, positive regulation of follicle-stimulating hormone secretion, regulation of cell cycle, regulation of cell proliferation, response to external stimulus, signal transduction, skeletal system development extracellular region, inhibin A complex, inhibin-betaglycan-ActRII complex, neuronal cell body, photoreceptor inner segment, photoreceptor outer segment cytokine activity, growth factor activity, hormone activity, inhibin binding, protein binding, protein heterodimerization activity, receptor binding Human INHBA BHF-UCL UniProtKB {GO:0042541=PMID:1310063, GO:0005515=PMID:12697670, GO:0030308=PMID:9884026, GO:0042701=PMID:10932194, GO:0030154=PMID:12456957, GO:0042802=PMID:2575216, GO:0071397=GO_REF:0000019, GO:0045077=PMID:12456957, GO:0001942=PMID:10932194, GO:0046982=GO_REF:0000019, GO:0046882=PMID:3267209, GO:0046881=PMID:12456957, GO:0006952=PMID:12456957, GO:0046880=PMID:10932194, GO:0045786=PMID:9884026, GO:0045650=PMID:12456957, GO:0005125=PMID:9884026, GO:0032925=PMID:9884026, GO:0005179=PMID:12456957, GO:0045648=PMID:9032295, GO:0045893=PMID:21281489, GO:0008083=PMID:12324653, GO:0040007=GO_REF:0000002, GO:0060279=GO_REF:0000024, GO:0045578=PMID:12456957, GO:0008285=PMID:11948405, GO:0007267=PMID:12456957, GO:0071372=GO_REF:0000019, GO:0001541=PMID:10932194, GO:0000082=PMID:9884026, GO:0070699=PMID:7890768, GO:0002244=PMID:15451575, GO:0045944=PMID:21281489, GO:0061029=GO_REF:0000024, GO:0042476=PMID:10932194, GO:0060021=PMID:10932194, GO:0007050=PMID:9884026, GO:0048333=GO_REF:0000019, GO:0043509=PMID:7890768, GO:0006357=PMID:11948405, GO:0010862=PMID:19736306, GO:0005576=Reactome:REACT_150395, GO:0006917=PMID:8267637, GO:0007399=PMID:10320815, GO:0042326=PMID:12456957, GO:0030218=PMID:1310063, GO:0043512=PMID:7890768, GO:0017046=PMID:16198295, GO:0007166=PMID:12456957, GO:0008584=PMID:10932194} P08476 Inhibin beta A chain protein 20120312 {GO:0042541=IDA, GO:0005515=IPI, GO:0030308=IDA, GO:0042701=IGI, GO:0030154=TAS, GO:0042802=IPI, GO:0071397=IEA, GO:0045077=TAS, GO:0001942=IGI, GO:0046982=IEA, GO:0046882=NAS, GO:0046881=TAS, GO:0006952=TAS, GO:0046880=IGI, GO:0045786=IDA, GO:0045650=TAS, GO:0005125=IDA, GO:0032925=IDA, GO:0005179=TAS, GO:0045648=IDA, GO:0045893=IDA, GO:0008083=TAS, GO:0040007=IEA, GO:0060279=ISS, GO:0045578=TAS, GO:0008285=IDA, GO:0007267=TAS, GO:0071372=IEA, GO:0001541=IGI, GO:0000082=IDA, GO:0070699=IPI, GO:0002244=IDA, GO:0045944=IDA, GO:0061029=ISS, GO:0042476=IGI, GO:0060021=IGI, GO:0007050=IDA, GO:0048333=IEA, GO:0043509=IDA, GO:0006357=IDA, GO:0010862=IDA, GO:0005576=TAS, GO:0006917=IDA, GO:0007399=NAS, GO:0042326=TAS, GO:0030218=NAS, GO:0043512=IDA, GO:0017046=IPI, GO:0007166=TAS, GO:0008584=IGI} G1/S transition of mitotic cell cycle, cell cycle arrest, cell differentiation, cell surface receptor signaling pathway, cell-cell signaling, cellular response to cholesterol, cellular response to follicle-stimulating hormone stimulus, defense response, erythrocyte differentiation, eyelid development in camera-type eye, growth, hair follicle development, hematopoietic progenitor cell differentiation, hemoglobin biosynthetic process, induction of apoptosis, male gonad development, mesodermal cell differentiation, negative regulation of B cell differentiation, negative regulation of cell cycle, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of follicle-stimulating hormone secretion, negative regulation of interferon-gamma biosynthetic process, negative regulation of macrophage differentiation, negative regulation of phosphorylation, nervous system development, odontogenesis, ovarian follicle development, palate development, positive regulation of erythrocyte differentiation, positive regulation of follicle-stimulating hormone secretion, positive regulation of ovulation, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, progesterone secretion, regulation of activin receptor signaling pathway, regulation of follicle-stimulating hormone secretion, regulation of transcription from RNA polymerase II promoter activin A complex, extracellular region, inhibin A complex cytokine activity, growth factor activity, hormone activity, identical protein binding, peptide hormone binding, protein binding, protein heterodimerization activity, type II activin receptor binding Human INHBB Reactome UniProtKB {GO:0005515=PMID:12697670, GO:0048471=PMID:16650820, GO:0048599=GO_REF:0000019, GO:0042803=PMID:2575216, GO:0030154=PMID:10320815, GO:0001541=PMID:12790766, GO:0044320=GO_REF:0000019, GO:0045444=GO_REF:0000024, GO:0046676=GO_REF:0000024, GO:0009267=GO_REF:0000024, GO:0032869=GO_REF:0000024, GO:0046882=PMID:3122219, GO:0046881=PMID:3122219, GO:0006952=PMID:3122219, GO:0005576=Reactome:REACT_150395, GO:0042981=GO_REF:0000019, GO:0032924=PMID:16650820, GO:0005125=PMID:3122219, GO:0009605=PMID:10320815, GO:0005179=PMID:3122219, GO:0046789=PMID:12456957, GO:0048178=PMID:12419948, GO:0008083=GO_REF:0000037, GO:0040007=GO_REF:0000002, GO:0060279=GO_REF:0000024} P09529 Inhibin beta B chain protein 20110715 {GO:0005515=IPI, GO:0048471=IDA, GO:0048599=IEA, GO:0042803=IPI, GO:0030154=NAS, GO:0001541=NAS, GO:0044320=IEA, GO:0045444=ISS, GO:0046676=ISS, GO:0009267=ISS, GO:0032869=ISS, GO:0046882=IPI, GO:0046881=IPI, GO:0006952=TAS, GO:0005576=TAS, GO:0042981=IEA, GO:0032924=IDA, GO:0005125=TAS, GO:0009605=IDA, GO:0005179=TAS, GO:0046789=TAS, GO:0048178=IDA, GO:0008083=IEA, GO:0040007=IEA, GO:0060279=ISS} activin receptor signaling pathway, cell differentiation, cellular response to insulin stimulus, cellular response to leptin stimulus, cellular response to starvation, defense response, fat cell differentiation, growth, negative regulation of follicle-stimulating hormone secretion, negative regulation of hepatocyte growth factor biosynthetic process, negative regulation of insulin secretion, oocyte development, ovarian follicle development, positive regulation of follicle-stimulating hormone secretion, positive regulation of ovulation, regulation of apoptotic process, response to external stimulus extracellular region, perinuclear region of cytoplasm cytokine activity, growth factor activity, hormone activity, host cell surface receptor binding, protein binding, protein homodimerization activity Human INHBC PINC UniProtKB {GO:0005179=GO_REF:0000037, GO:0005576=GO_REF:0000039, GO:0005160=PMID:7826378, GO:0008083=GO_REF:0000037, GO:0040007=GO_REF:0000002} P55103 Inhibin beta C chain protein 20030904 {GO:0005179=IEA, GO:0005576=IEA, GO:0005160=TAS, GO:0008083=IEA, GO:0040007=IEA} growth extracellular region growth factor activity, hormone activity, transforming growth factor beta receptor binding Human INHBE UniProtKB UniProtKB {GO:0005179=GO_REF:0000037, GO:0005576=GO_REF:0000039, GO:0040007=GO_REF:0000002, GO:0008083=GO_REF:0000037} P58166 Inhibin beta E chain protein 20130413 {GO:0005179=IEA, GO:0005576=IEA, GO:0040007=IEA, GO:0008083=IEA} growth extracellular region growth factor activity, hormone activity Human UniProtKB-SubCell:SL-0243 INO80 GOC UniProtKB {GO:0005515=PMID:20855601, GO:0016817=GO_REF:0000002, GO:0006200=PMID:16298340, GO:0030307=PMID:20237820, GO:0005634=PMID:18026119, GO:2000045=PMID:20237820, GO:0006302=PMID:20687897, GO:0034644=PMID:18026119, GO:0000724=PMID:18026119, GO:0045944=PMID:20687897, GO:0010571=PMID:20237820, GO:0006338=PMID:16298340, GO:0032508=PMID:16298340, GO:0016887=PMID:16298340, GO:0043014=PMID:20237820, GO:0005874=GO_REF:0000037, GO:0003779=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0003677=PMID:16298340, GO:0051225=PMID:20237820, GO:0003678=PMID:16298340, GO:0071479=PMID:20687897, GO:0031011=PMID:21303910, GO:0000070=PMID:20237820, GO:0070914=PMID:20855601, GO:0051301=GO_REF:0000037} Q9ULG1 DNA helicase INO80 protein 20130413 {GO:0005515=IPI, GO:0016817=IEA, GO:0006200=IDA, GO:0030307=IMP, GO:0005634=IDA, GO:2000045=IMP, GO:0006302=IMP, GO:0034644=IMP, GO:0000724=IMP, GO:0045944=IMP, GO:0010571=IMP, GO:0006338=IDA, GO:0032508=IDA, GO:0016887=IDA, GO:0043014=IMP, GO:0005874=IEA, GO:0003779=IEA, GO:0005524=IEA, GO:0003677=IDA, GO:0051225=IMP, GO:0003678=IDA, GO:0071479=IMP, GO:0031011=IDA, GO:0000070=IMP, GO:0070914=IMP, GO:0051301=IEA} ATP catabolic process, DNA duplex unwinding, UV-damage excision repair, cell division, cellular response to UV, cellular response to ionizing radiation, chromatin remodeling, double-strand break repair, double-strand break repair via homologous recombination, mitotic sister chromatid segregation, positive regulation of DNA replication involved in S phase, positive regulation of cell growth, positive regulation of transcription from RNA polymerase II promoter, regulation of G1/S transition of mitotic cell cycle, spindle assembly Ino80 complex, microtubule, nucleus ATP binding, ATPase activity, DNA binding, DNA helicase activity, actin binding, alpha-tubulin binding, hydrolase activity, acting on acid anhydrides, protein binding Human INO80B HPA UniProtKB {GO:0031011=PMID:21303910, GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0006281=GO_REF:0000037, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0006310=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9C086 INO80 complex subunit B protein 20111111 {GO:0031011=IDA, GO:0005737=IDA, GO:0006355=IEA, GO:0006281=IEA, GO:0005886=IDA, GO:0005730=IEA, GO:0005634=IDA, GO:0006310=IEA, GO:0046872=IEA, GO:0006351=IEA} DNA recombination, DNA repair, regulation of transcription, DNA-dependent, transcription, DNA-dependent Ino80 complex, cytoplasm, nucleolus, nucleus, plasma membrane metal ion binding Human INO80C HPA UniProtKB {GO:0031011=PMID:21303910, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0006355=GO_REF:0000037, GO:0006281=GO_REF:0000037, GO:0071339=PMID:15960975, GO:0005730=GO_REF:0000052, GO:0006310=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6PI98 INO80 complex subunit C protein 20120912 {GO:0031011=IDA, GO:0008150=ND, GO:0003674=ND, GO:0006355=IEA, GO:0006281=IEA, GO:0071339=IDA, GO:0005730=IDA, GO:0006310=IEA, GO:0006351=IEA} DNA recombination, DNA repair, biological_process, regulation of transcription, DNA-dependent, transcription, DNA-dependent Ino80 complex, MLL1 complex, nucleolus molecular_function Human INO80D UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0006281=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006310=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q53TQ3 INO80 complex subunit D protein 20130413 {GO:0006355=IEA, GO:0006281=IEA, GO:0005634=IEA, GO:0006310=IEA, GO:0006351=IEA} DNA recombination, DNA repair, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus Human UniProtKB-SubCell:SL-0191 INO80E HPA UniProtKB {GO:0006260=GO_REF:0000002, GO:0031011=PMID:21303910, GO:0006355=GO_REF:0000037, GO:0006281=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006310=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8NBZ0 INO80 complex subunit E protein 20111111 {GO:0006260=IEA, GO:0031011=IDA, GO:0006355=IEA, GO:0006281=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006310=IEA, GO:0006351=IEA} DNA recombination, DNA repair, DNA replication, regulation of transcription, DNA-dependent, transcription, DNA-dependent Ino80 complex, nucleolus, nucleus Human INPP1 Reactome UniProtKB {GO:0007165=PMID:8390685, GO:0046854=GO_REF:0000002, GO:0043647=Reactome:REACT_150352, GO:0044281=Reactome:REACT_111217, GO:0006796=PMID:8390685, GO:0052829=Reactome:REACT_150176, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_150296, GO:0004441=Reactome:REACT_150296} P49441 Inositol polyphosphate 1-phosphatase protein 20111213 {GO:0007165=TAS, GO:0046854=IEA, GO:0043647=TAS, GO:0044281=TAS, GO:0006796=TAS, GO:0052829=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0004441=TAS} inositol phosphate metabolic process, phosphate-containing compound metabolic process, phosphatidylinositol phosphorylation, signal transduction, small molecule metabolic process cytosol inositol-1,3,4-trisphosphate 1-phosphatase activity, inositol-1,4-bisphosphate 1-phosphatase activity, metal ion binding Human INPP4A Reactome UniProtKB {GO:0007165=PMID:7608176, GO:0043647=Reactome:REACT_150352, GO:0006661=Reactome:REACT_121025, GO:0034597=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0006644=Reactome:REACT_121175, GO:0016316=GO_REF:0000003, GO:0005829=Reactome:REACT_150323} Q96PE3 Type I inositol 3,4-bisphosphate 4-phosphatase protein 20130301 {GO:0007165=TAS, GO:0043647=TAS, GO:0006661=TAS, GO:0034597=IEA, GO:0044281=TAS, GO:0006644=TAS, GO:0016316=IEA, GO:0005829=TAS} inositol phosphate metabolic process, phosphatidylinositol biosynthetic process, phospholipid metabolic process, signal transduction, small molecule metabolic process cytosol phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity, phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity Human INPP4B Reactome UniProtKB {GO:0007165=PMID:9295334, GO:0043647=Reactome:REACT_150352, GO:0006661=Reactome:REACT_121025, GO:0034597=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0006644=Reactome:REACT_121175, GO:0016316=GO_REF:0000003, GO:0005829=Reactome:REACT_150323} O15327 Type II inositol 3,4-bisphosphate 4-phosphatase protein 20130301 {GO:0007165=TAS, GO:0043647=TAS, GO:0006661=TAS, GO:0034597=IEA, GO:0044281=TAS, GO:0006644=TAS, GO:0016316=IEA, GO:0005829=TAS} inositol phosphate metabolic process, phosphatidylinositol biosynthetic process, phospholipid metabolic process, signal transduction, small molecule metabolic process cytosol phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity, phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity Human INPP5A InterPro UniProtKB {GO:0007154=GO_REF:0000029, GO:0043647=Reactome:REACT_150352, GO:0005886=Reactome:REACT_150429, GO:0016020=PMID:8006039, GO:0052658=GO_REF:0000003, GO:0052659=GO_REF:0000003, GO:0046856=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0004445=PMID:8006039, GO:0042731=PMID:8999861} Q5T1B5 Type I inositol 1,4,5-trisphosphate 5-phosphatase protein 20130413 {GO:0007154=NAS, GO:0043647=TAS, GO:0005886=TAS, GO:0016020=NAS, GO:0052658=IEA, GO:0052659=IEA, GO:0046856=IEA, GO:0044281=TAS, GO:0004445=NAS, GO:0042731=IPI} cell communication, inositol phosphate metabolic process, phosphatidylinositol dephosphorylation, small molecule metabolic process membrane, plasma membrane PH domain binding, inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity, inositol-1,4,5-trisphosphate 5-phosphatase activity, inositol-polyphosphate 5-phosphatase activity Human InterPro:IPR000300 INPP5B HPA UniProtKB {GO:0005515=PMID:21233288, GO:0051056=Reactome:REACT_11051, GO:0005793=GO_REF:0000039, GO:0005794=GO_REF:0000039, GO:0043647=Reactome:REACT_150352, GO:0005886=Reactome:REACT_150429, GO:0052658=PMID:7721860, GO:0007264=Reactome:REACT_11044, GO:0070613=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0007283=GO_REF:0000019, GO:0030317=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_9982, GO:0004439=PMID:7721860, GO:0005737=GO_REF:0000052, GO:0016020=PMID:7721860, GO:0031901=GO_REF:0000039, GO:0046856=PMID:7721860, GO:0015630=GO_REF:0000052, GO:0030670=GO_REF:0000039, GO:0016021=GO_REF:0000019} P32019 Type II inositol 1,4,5-trisphosphate 5-phosphatase protein 20101115 {GO:0005515=IPI, GO:0051056=TAS, GO:0005793=IEA, GO:0005794=IEA, GO:0043647=TAS, GO:0005886=TAS, GO:0052658=IDA, GO:0007264=TAS, GO:0070613=IEA, GO:0044281=TAS, GO:0007283=IEA, GO:0030317=IEA, GO:0001701=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0004439=IDA, GO:0005737=IDA, GO:0016020=IDA, GO:0031901=IEA, GO:0046856=IDA, GO:0015630=IDA, GO:0030670=IEA, GO:0016021=IEA} in utero embryonic development, inositol phosphate metabolic process, phosphatidylinositol dephosphorylation, regulation of protein processing, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction, small molecule metabolic process, sperm motility, spermatogenesis Golgi apparatus, cytoplasm, cytosol, early endosome membrane, endoplasmic reticulum-Golgi intermediate compartment, integral to membrane, membrane, microtubule cytoskeleton, phagocytic vesicle membrane, plasma membrane inositol-1,4,5-trisphosphate 5-phosphatase activity, metal ion binding, phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, protein binding Human INPP5D Reactome UniProtKB {GO:0005515=PMID:21712384, GO:0050852=Reactome:REACT_12526, GO:0017124=GO_REF:0000019, GO:0016064=GO_REF:0000019, GO:0043647=Reactome:REACT_150312, GO:0045579=GO_REF:0000019, GO:0045409=GO_REF:0000019, GO:0051425=GO_REF:0000019, GO:0034594=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0006796=PMID:8769125, GO:0050900=Reactome:REACT_12051, GO:0008340=GO_REF:0000019, GO:0045779=GO_REF:0000019, GO:0005829=Reactome:REACT_150220, GO:0035556=GO_REF:0000019, GO:0005622=GO_REF:0000019, GO:0045656=GO_REF:0000019, GO:0045659=GO_REF:0000019, GO:0009968=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0006661=Reactome:REACT_121025, GO:0030889=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0045671=GO_REF:0000019, GO:0004445=GO_REF:0000019, GO:0007165=PMID:8769125, GO:0050777=GO_REF:0000019, GO:0016020=GO_REF:0000039, GO:0007596=Reactome:REACT_604, GO:0045648=GO_REF:0000019, GO:0046856=GO_REF:0000002, GO:0006644=Reactome:REACT_121175} Q92835 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 protein 20111102 {GO:0005515=IPI, GO:0050852=TAS, GO:0017124=IEA, GO:0016064=IEA, GO:0043647=TAS, GO:0045579=IEA, GO:0045409=IEA, GO:0051425=IEA, GO:0034594=IEA, GO:0044281=TAS, GO:0006796=TAS, GO:0050900=TAS, GO:0008340=IEA, GO:0045779=IEA, GO:0005829=TAS, GO:0035556=IEA, GO:0005622=IEA, GO:0045656=IEA, GO:0045659=IEA, GO:0009968=IEA, GO:0043065=IEA, GO:0006661=TAS, GO:0030889=IEA, GO:0006915=IEA, GO:0045671=IEA, GO:0004445=IEA, GO:0007165=TAS, GO:0050777=IEA, GO:0016020=IEA, GO:0007596=TAS, GO:0045648=IEA, GO:0046856=IEA, GO:0006644=TAS} T cell receptor signaling pathway, apoptotic process, blood coagulation, determination of adult lifespan, immunoglobulin mediated immune response, inositol phosphate metabolic process, intracellular signal transduction, leukocyte migration, negative regulation of B cell proliferation, negative regulation of bone resorption, negative regulation of immune response, negative regulation of interleukin-6 biosynthetic process, negative regulation of monocyte differentiation, negative regulation of neutrophil differentiation, negative regulation of osteoclast differentiation, negative regulation of signal transduction, phosphate-containing compound metabolic process, phosphatidylinositol biosynthetic process, phosphatidylinositol dephosphorylation, phospholipid metabolic process, positive regulation of B cell differentiation, positive regulation of apoptotic process, positive regulation of erythrocyte differentiation, signal transduction, small molecule metabolic process cytosol, intracellular, membrane PTB domain binding, SH3 domain binding, inositol-polyphosphate 5-phosphatase activity, phosphatidylinositol trisphosphate phosphatase activity, protein binding Human INPP5E Reactome UniProtKB {GO:0008150=GO_REF:0000015, GO:0004439=GO_REF:0000003, GO:0006661=Reactome:REACT_120836, GO:0032580=GO_REF:0000039, GO:0046855=GO_REF:0000019, GO:0046856=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0004445=PMID:10764818, GO:0006644=Reactome:REACT_121175, GO:0035085=PMID:19668215, GO:0005856=GO_REF:0000037, GO:0005829=Reactome:REACT_120928} Q9NRR6 72 kDa inositol polyphosphate 5-phosphatase protein 20130301 {GO:0008150=ND, GO:0004439=IEA, GO:0006661=TAS, GO:0032580=IEA, GO:0046855=IEA, GO:0046856=IEA, GO:0044281=TAS, GO:0004445=TAS, GO:0006644=TAS, GO:0035085=IDA, GO:0005856=IEA, GO:0005829=TAS} biological_process, inositol phosphate dephosphorylation, phosphatidylinositol biosynthetic process, phosphatidylinositol dephosphorylation, phospholipid metabolic process, small molecule metabolic process Golgi cisterna membrane, cilium axoneme, cytoskeleton, cytosol inositol-polyphosphate 5-phosphatase activity, phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity Human INPP5K IntAct UniProtKB {GO:0005515=PMID:16002321, GO:0005802=PMID:12556481, GO:0034595=PMID:18774950, GO:0034594=PMID:12556481, GO:0005000=GO_REF:0000024, GO:0071356=PMID:21712384, GO:0097178=PMID:12556481, GO:0051926=PMID:12556481, GO:2000466=GO_REF:0000024, GO:0032868=GO_REF:0000019, GO:0005979=GO_REF:0000024, GO:0032869=PMID:12556481, GO:0046030=PMID:10753883, GO:0090315=PMID:12556481, GO:0001701=GO_REF:0000019, GO:0034485=PMID:21712384, GO:0043922=PMID:18774950, GO:0051497=PMID:12556481, GO:0007186=GO_REF:0000024, GO:0016311=PMID:18774950, GO:0016312=PMID:10753883, GO:2001153=GO_REF:0000024, GO:0006644=Reactome:REACT_121175, GO:0035810=GO_REF:0000024, GO:0045893=GO_REF:0000024, GO:0045892=GO_REF:0000024, GO:0051898=PMID:12556481, GO:0043005=PMID:10753883, GO:0048471=PMID:21712384, GO:0030036=PMID:10753883, GO:0005783=PMID:12536145, GO:0072661=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0032870=GO_REF:0000024, GO:0005829=Reactome:REACT_121166, GO:0005737=GO_REF:0000024, GO:0042577=PMID:10753883, GO:0033137=GO_REF:0000019, GO:0043407=PMID:12556481, GO:0006661=Reactome:REACT_121025, GO:0052658=GO_REF:0000003, GO:0035305=GO_REF:0000024, GO:0052659=GO_REF:0000003, GO:0046627=PMID:12556481, GO:0045869=PMID:18774950, GO:0032587=PMID:12556481, GO:0004445=GO_REF:0000003, GO:0042593=GO_REF:0000024, GO:0010829=PMID:12556481, GO:0001726=PMID:12536145, GO:0045719=PMID:12556481, GO:0016020=PMID:12536145, GO:0071364=PMID:21712384, GO:0046855=PMID:12536145, GO:0046856=PMID:12536145, GO:0001933=GO_REF:0000024, GO:0071320=GO_REF:0000024} Q9BT40 Inositol polyphosphate 5-phosphatase K protein 20130415 {GO:0005515=IPI, GO:0005802=IDA, GO:0034595=IMP, GO:0034594=IDA, GO:0005000=ISS, GO:0071356=IDA, GO:0097178=IDA, GO:0051926=IDA, GO:2000466=ISS, GO:0032868=IEA, GO:0005979=ISS, GO:0032869=IDA, GO:0046030=IDA, GO:0090315=IDA, GO:0001701=IEA, GO:0034485=IDA, GO:0043922=IDA, GO:0051497=IDA, GO:0007186=ISS, GO:0016311=IMP, GO:0016312=IDA, GO:2001153=ISS, GO:0006644=TAS, GO:0035810=ISS, GO:0045893=ISS, GO:0045892=ISS, GO:0051898=IDA, GO:0043005=IDA, GO:0048471=IDA, GO:0030036=NAS, GO:0005783=IDA, GO:0072661=ISS, GO:0044281=TAS, GO:0032870=ISS, GO:0005829=TAS, GO:0005737=ISS, GO:0042577=NAS, GO:0033137=IEA, GO:0043407=IDA, GO:0006661=TAS, GO:0052658=IEA, GO:0035305=ISS, GO:0052659=IEA, GO:0046627=IDA, GO:0045869=IDA, GO:0032587=IDA, GO:0004445=IEA, GO:0042593=ISS, GO:0010829=IDA, GO:0001726=IDA, GO:0045719=IDA, GO:0016020=IDA, GO:0071364=IDA, GO:0046855=IDA, GO:0046856=IDA, GO:0001933=ISS, GO:0071320=ISS} G-protein coupled receptor signaling pathway, actin cytoskeleton organization, cellular response to cAMP, cellular response to epidermal growth factor stimulus, cellular response to hormone stimulus, cellular response to insulin stimulus, cellular response to tumor necrosis factor, dephosphorylation, glucose homeostasis, in utero embryonic development, inositol phosphate dephosphorylation, negative regulation by host of viral transcription, negative regulation of MAP kinase activity, negative regulation of calcium ion transport, negative regulation of dephosphorylation, negative regulation of glucose transport, negative regulation of glycogen (starch) synthase activity, negative regulation of glycogen biosynthetic process, negative regulation of insulin receptor signaling pathway, negative regulation of peptidyl-serine phosphorylation, negative regulation of protein kinase B signaling cascade, negative regulation of protein phosphorylation, negative regulation of protein targeting to membrane, negative regulation of retroviral genome replication, negative regulation of stress fiber assembly, negative regulation of transcription, DNA-dependent, phosphatidylinositol biosynthetic process, phosphatidylinositol dephosphorylation, phospholipid metabolic process, positive regulation of renal water transport, positive regulation of transcription, DNA-dependent, positive regulation of urine volume, protein targeting to plasma membrane, regulation of glycogen biosynthetic process, response to insulin stimulus, ruffle assembly, small molecule metabolic process cytoplasm, cytosol, endoplasmic reticulum, membrane, neuron projection, perinuclear region of cytoplasm, ruffle, ruffle membrane, trans-Golgi network inositol bisphosphate phosphatase activity, inositol trisphosphate phosphatase activity, inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity, inositol-1,4,5-trisphosphate 5-phosphatase activity, inositol-polyphosphate 5-phosphatase activity, lipid phosphatase activity, phosphatidylinositol phosphate 5-phosphatase activity, phosphatidylinositol trisphosphate phosphatase activity, phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity, protein binding, vasopressin receptor activity Human UniProtKB:Q8TBB1 INPPL1 HPA UniProtKB {GO:0005515=PMID:20368287, GO:0017124=GO_REF:0000037, GO:0008285=GO_REF:0000019, GO:0043647=Reactome:REACT_150312, GO:0005886=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0030175=GO_REF:0000039, GO:0009791=GO_REF:0000019, GO:0005829=Reactome:REACT_150220, GO:0005737=GO_REF:0000052, GO:0032957=GO_REF:0000019, GO:0043407=GO_REF:0000019, GO:0006006=GO_REF:0000019, GO:0097178=GO_REF:0000019, GO:0007015=PMID:15668240, GO:0010642=GO_REF:0000019, GO:0007155=PMID:15668240, GO:0005856=GO_REF:0000039, GO:0042169=PMID:5668240, GO:0032868=GO_REF:0000019, GO:0005794=GO_REF:0000052, GO:0006661=Reactome:REACT_121025, GO:0042493=GO_REF:0000019, GO:0046627=GO_REF:0000019, GO:0005547=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0004445=GO_REF:0000019, GO:0030027=GO_REF:0000039, GO:0006897=PMID:15668240, GO:0043569=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0010629=GO_REF:0000019, GO:0046856=GO_REF:0000002, GO:0010977=GO_REF:0000019, GO:0008156=GO_REF:0000019, GO:0006644=Reactome:REACT_121175} O15357 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 protein 20110516 {GO:0005515=IPI, GO:0017124=IEA, GO:0008285=IEA, GO:0043647=TAS, GO:0005886=IEA, GO:0044281=TAS, GO:0030175=IEA, GO:0009791=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0032957=IEA, GO:0043407=IEA, GO:0006006=IEA, GO:0097178=IEA, GO:0007015=IMP, GO:0010642=IEA, GO:0007155=TAS, GO:0005856=IEA, GO:0042169=IPI, GO:0032868=IEA, GO:0005794=IDA, GO:0006661=TAS, GO:0042493=IEA, GO:0046627=IEA, GO:0005547=IEA, GO:0003779=IEA, GO:0004445=IEA, GO:0030027=IEA, GO:0006897=IMP, GO:0043569=IEA, GO:0007420=IEA, GO:0010629=IEA, GO:0046856=IEA, GO:0010977=IEA, GO:0008156=IEA, GO:0006644=TAS} actin filament organization, brain development, cell adhesion, endocytosis, glucose metabolic process, inositol phosphate metabolic process, inositol trisphosphate metabolic process, negative regulation of DNA replication, negative regulation of MAP kinase activity, negative regulation of cell proliferation, negative regulation of gene expression, negative regulation of insulin receptor signaling pathway, negative regulation of insulin-like growth factor receptor signaling pathway, negative regulation of neuron projection development, negative regulation of platelet-derived growth factor receptor signaling pathway, phosphatidylinositol biosynthetic process, phosphatidylinositol dephosphorylation, phospholipid metabolic process, post-embryonic development, response to drug, response to insulin stimulus, ruffle assembly, small molecule metabolic process Golgi apparatus, cytoplasm, cytoskeleton, cytosol, filopodium, lamellipodium, plasma membrane SH2 domain binding, SH3 domain binding, actin binding, inositol-polyphosphate 5-phosphatase activity, phosphatidylinositol-3,4,5-trisphosphate binding, protein binding Human INS BHF-UCL UniProtKB {GO:0005515=PMID:9388210, GO:0005159=PMID:8452530, GO:0030307=PMID:11742412, GO:0005158=PMID:8452530, GO:0046631=PMID:10604997, GO:0045597=PMID:11742412, GO:2000252=PMID:17957153, GO:0050731=PMID:11278339, GO:0002020=PMID:20082125, GO:0005615=PMID:9667398, GO:0046889=PMID:11742412, GO:0045922=PMID:1184755, GO:0015758=PMID:14615391, GO:0000165=PMID:11278339, GO:0046326=PMID:14615391, GO:0045821=PMID:381941, GO:0030335=PMID:12138094, GO:0005796=Reactome:REACT_15512, GO:0045740=PMID:7688386, GO:0014068=PMID:7688386, GO:0045840=PMID:11500939, GO:0006953=PMID:14739855, GO:0002674=PMID:11443198, GO:0032270=PMID:3553851, GO:0005179=PMID:381941, GO:0007186=PMID:9092559, GO:0051000=PMID:12135947, GO:0042060=PMID:9498508, GO:0050709=PMID:14739855, GO:0005788=Reactome:REACT_15512, GO:0050708=PMID:15591776, GO:0044267=Reactome:REACT_17015, GO:0034774=Reactome:REACT_15374, GO:0008286=Reactome:REACT_498, GO:0051897=PMID:11500939, GO:0008284=PMID:17925406, GO:0050995=PMID:11742412, GO:0007267=PMID:7556975, GO:0050715=PMID:15473891, GO:0044281=Reactome:REACT_111217, GO:0060266=PMID:11443198, GO:0060267=PMID:9092559, GO:0045429=PMID:14615391, GO:0032880=PMID:14615391, GO:0051092=PMID:19727662, GO:0045909=PMID:14744991, GO:0032148=PMID:8702995, GO:0045908=PMID:12946932, GO:0006006=GO_REF:0000037, GO:0033861=PMID:11443198, GO:0031954=PMID:3518947, GO:0045721=PMID:11742412, GO:0043066=PMID:16604263, GO:0006355=PMID:12881524, GO:0022898=PMID:14615391, GO:0045725=PMID:17925406, GO:0042177=PMID:15185208, GO:0006521=PMID:3553851, GO:0046628=PMID:7688386, GO:0055089=PMID:1184755, GO:0005576=Reactome:REACT_75905, GO:0042593=PMID:381941, GO:0090336=PMID:11387233, GO:0045861=PMID:3553851, GO:0031904=Reactome:REACT_1355, GO:0045818=PMID:381941, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0031018=Reactome:REACT_13819, GO:0043410=PMID:11500939} P01308 Insulin protein 20130111 {GO:0005515=IPI, GO:0005159=IPI, GO:0030307=NAS, GO:0005158=IPI, GO:0046631=IDA, GO:0045597=NAS, GO:2000252=IDA, GO:0050731=IDA, GO:0002020=IPI, GO:0005615=IDA, GO:0046889=NAS, GO:0045922=IMP, GO:0015758=IDA, GO:0000165=IDA, GO:0046326=IDA, GO:0045821=IMP, GO:0030335=ISS, GO:0005796=TAS, GO:0045740=IDA, GO:0014068=IDA, GO:0045840=IDA, GO:0006953=IDA, GO:0002674=IDA, GO:0032270=IMP, GO:0005179=IMP, GO:0007186=IDA, GO:0051000=NAS, GO:0042060=IDA, GO:0050709=IDA, GO:0005788=TAS, GO:0050708=IDA, GO:0044267=TAS, GO:0034774=TAS, GO:0008286=TAS, GO:0051897=IDA, GO:0008284=IDA, GO:0050995=NAS, GO:0007267=IC, GO:0050715=IDA, GO:0044281=TAS, GO:0060266=IDA, GO:0060267=IDA, GO:0045429=NAS, GO:0032880=IDA, GO:0051092=IDA, GO:0045909=NAS, GO:0032148=IDA, GO:0045908=NAS, GO:0006006=IEA, GO:0033861=IDA, GO:0031954=ISS, GO:0045721=NAS, GO:0043066=NAS, GO:0006355=NAS, GO:0022898=IDA, GO:0045725=IDA, GO:0042177=IDA, GO:0006521=IMP, GO:0046628=IDA, GO:0055089=IMP, GO:0005576=TAS, GO:0042593=IMP, GO:0090336=TAS, GO:0045861=IMP, GO:0031904=TAS, GO:0045818=IMP, GO:0006112=TAS, GO:0050796=TAS, GO:0031018=TAS, GO:0043410=IDA} G-protein coupled receptor signaling pathway, MAPK cascade, activation of protein kinase B activity, acute-phase response, alpha-beta T cell activation, cell-cell signaling, cellular protein metabolic process, endocrine pancreas development, energy reserve metabolic process, fatty acid homeostasis, glucose homeostasis, glucose metabolic process, glucose transport, insulin receptor signaling pathway, negative regulation of NAD(P)H oxidase activity, negative regulation of acute inflammatory response, negative regulation of apoptotic process, negative regulation of fatty acid metabolic process, negative regulation of feeding behavior, negative regulation of gluconeogenesis, negative regulation of glycogen catabolic process, negative regulation of lipid catabolic process, negative regulation of protein catabolic process, negative regulation of protein secretion, negative regulation of proteolysis, negative regulation of respiratory burst involved in inflammatory response, negative regulation of vasodilation, positive regulation of DNA replication, positive regulation of MAPK cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of brown fat cell differentiation, positive regulation of cell differentiation, positive regulation of cell growth, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of cellular protein metabolic process, positive regulation of cytokine secretion, positive regulation of glucose import, positive regulation of glycogen biosynthetic process, positive regulation of glycolysis, positive regulation of insulin receptor signaling pathway, positive regulation of lipid biosynthetic process, positive regulation of mitosis, positive regulation of nitric oxide biosynthetic process, positive regulation of nitric-oxide synthase activity, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of protein autophosphorylation, positive regulation of protein kinase B signaling cascade, positive regulation of respiratory burst, positive regulation of vasodilation, regulation of cellular amino acid metabolic process, regulation of insulin secretion, regulation of protein localization, regulation of protein secretion, regulation of transcription, DNA-dependent, regulation of transmembrane transporter activity, small molecule metabolic process, wound healing Golgi lumen, endoplasmic reticulum lumen, endosome lumen, extracellular region, extracellular space, secretory granule lumen hormone activity, insulin receptor binding, insulin-like growth factor receptor binding, protease binding, protein binding Human INSC UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0060487=GO_REF:0000019, GO:0000132=GO_REF:0000019, GO:0045177=GO_REF:0000019, GO:0007399=GO_REF:0000037} Q1MX18 Protein inscuteable homolog protein 20130413 {GO:0005737=IEA, GO:0060487=IEA, GO:0000132=IEA, GO:0045177=IEA, GO:0007399=IEA} establishment of mitotic spindle orientation, lung epithelial cell differentiation, nervous system development apical part of cell, cytoplasm Human UniProtKB-SubCell:SL-0086 INSIG1 IntAct UniProtKB {GO:0005515=PMID:21081644, GO:0006695=GO_REF:0000019, GO:0042472=GO_REF:0000019, GO:0006991=GO_REF:0000019, GO:0008283=PMID:9268630, GO:0045599=GO_REF:0000019, GO:0005783=PMID:12202038, GO:0045717=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0010894=GO_REF:0000019, GO:0060363=GO_REF:0000019, GO:0032933=PMID:12242332, GO:1901303=PMID:15899885, GO:0008152=PMID:9268630, GO:0032937=PMID:15899885, GO:0005789=Reactome:REACT_147840, GO:0006641=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:0042474=GO_REF:0000019} O15503 Insulin-induced gene 1 protein protein 20130415 {GO:0005515=IPI, GO:0006695=IEA, GO:0042472=IEA, GO:0006991=IEA, GO:0008283=TAS, GO:0045599=IEA, GO:0005783=IDA, GO:0045717=IEA, GO:0044281=TAS, GO:0010894=IEA, GO:0060363=IEA, GO:0032933=IDA, GO:1901303=IMP, GO:0008152=TAS, GO:0032937=IDA, GO:0005789=TAS, GO:0006641=IEA, GO:0060021=IEA, GO:0042474=IEA} SREBP signaling pathway, cell proliferation, cholesterol biosynthetic process, cranial suture morphogenesis, inner ear morphogenesis, metabolic process, middle ear morphogenesis, negative regulation of cargo loading into COPII-coated vesicle, negative regulation of fat cell differentiation, negative regulation of fatty acid biosynthetic process, negative regulation of steroid biosynthetic process, palate development, response to sterol depletion, small molecule metabolic process, triglyceride metabolic process SREBP-SCAP-Insig complex, endoplasmic reticulum, endoplasmic reticulum membrane protein binding Human UniProtKB:P00181 INSIG2 Reactome UniProtKB {GO:0005515=PMID:12242332, GO:0006695=GO_REF:0000019, GO:0032868=GO_REF:0000019, GO:0042472=GO_REF:0000019, GO:0045717=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0010894=GO_REF:0000019, GO:0060363=GO_REF:0000019, GO:0070542=GO_REF:0000019, GO:0032933=PMID:12242332, GO:0032937=PMID:12242332, GO:0005789=Reactome:REACT_147840, GO:0006641=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:0042474=GO_REF:0000019, GO:0008134=GO_REF:0000019} Q9Y5U4 Insulin-induced gene 2 protein protein 20130301 {GO:0005515=IPI, GO:0006695=IEA, GO:0032868=IEA, GO:0042472=IEA, GO:0045717=IEA, GO:0044281=TAS, GO:0010894=IEA, GO:0060363=IEA, GO:0070542=IEA, GO:0032933=IDA, GO:0032937=IDA, GO:0005789=TAS, GO:0006641=IEA, GO:0060021=IEA, GO:0042474=IEA, GO:0008134=IEA} SREBP signaling pathway, cholesterol biosynthetic process, cranial suture morphogenesis, inner ear morphogenesis, middle ear morphogenesis, negative regulation of fatty acid biosynthetic process, negative regulation of steroid biosynthetic process, palate development, response to fatty acid, response to insulin stimulus, small molecule metabolic process, triglyceride metabolic process SREBP-SCAP-Insig complex, endoplasmic reticulum membrane protein binding, transcription factor binding Human INSL3 Reactome UniProtKB {GO:0008284=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0001664=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0005158=PMID:8253799, GO:0030819=GO_REF:0000019, GO:0007267=PMID:8253799, GO:0005102=PMID:8020942, GO:0005576=Reactome:REACT_22268, GO:0007283=PMID:8253799, GO:0001556=GO_REF:0000019, GO:0002020=PMID:20082125, GO:0005615=GO_REF:0000019, GO:0007193=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0005179=GO_REF:0000037, GO:0008584=GO_REF:0000019} P51460 Insulin-like 3 protein 20091027 {GO:0008284=IEA, GO:0043066=IEA, GO:0048471=IEA, GO:0001664=IEA, GO:0008285=IEA, GO:0005158=TAS, GO:0030819=IEA, GO:0007267=TAS, GO:0005102=TAS, GO:0005576=TAS, GO:0007283=TAS, GO:0001556=IEA, GO:0002020=IPI, GO:0005615=IEA, GO:0007193=IEA, GO:0001701=IEA, GO:0005179=IEA, GO:0008584=IEA} adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, cell-cell signaling, in utero embryonic development, male gonad development, negative regulation of apoptotic process, negative regulation of cell proliferation, oocyte maturation, positive regulation of cAMP biosynthetic process, positive regulation of cell proliferation, spermatogenesis extracellular region, extracellular space, perinuclear region of cytoplasm G-protein coupled receptor binding, hormone activity, insulin receptor binding, protease binding, receptor binding Human INSM1 Reactome UniProtKB {GO:0006355=GO_REF:0000037, GO:0031018=Reactome:REACT_13698, GO:0005654=Reactome:REACT_13811, GO:0003323=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q01101 Insulinoma-associated protein 1 protein 20130301 {GO:0006355=IEA, GO:0031018=TAS, GO:0005654=TAS, GO:0003323=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} endocrine pancreas development, regulation of transcription, DNA-dependent, transcription, DNA-dependent, type B pancreatic cell development nucleoplasm DNA binding, zinc ion binding Human INSM2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96T92 Insulinoma-associated protein 2 protein 20130413 {GO:0005737=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0086 INSR GOC UniProtKB {GO:0005515=PMID:11289049, GO:0005159=PMID:8452530, GO:0043560=PMID:7537849, GO:0046777=PMID:8496180, GO:0005899=PMID:15069075, GO:0046326=PMID:11001060, GO:0045821=PMID:7693131, GO:0042169=PMID:8276809, GO:0043559=PMID:8452530, GO:0023014=PMID:6849137, GO:0032869=PMID:8440175, GO:0030335=PMID:12138094, GO:0005975=GO_REF:0000037, GO:0045740=PMID:12138094, GO:0018108=PMID:8496180, GO:0045840=PMID:11500939, GO:0007186=PMID:9092559, GO:0005887=PMID:9092559, GO:0048639=PMID:7693131, GO:0010008=Reactome:REACT_599, GO:0043548=PMID:7537849, GO:0008286=PMID:6849137, GO:0051897=PMID:11500939, GO:0008284=PMID:11500939, GO:0005886=PMID:6849137, GO:0031994=PMID:8452530, GO:0051425=PMID:7559478, GO:0031995=PMID:12138094, GO:0051290=PMID:1898103, GO:0060267=PMID:9092559, GO:0045429=PMID:10747347, GO:0032147=PMID:9819385, GO:0000187=PMID:17001305, GO:0030238=GO_REF:0000019, GO:0032148=PMID:7556070, GO:0019087=PMID:17001305, GO:0006355=PMID:12881524, GO:0005009=PMID:6849137, GO:0045725=PMID:17925406, GO:0042593=PMID:7693131, GO:0005525=PMID:9092559, GO:0005524=PMID:6849137, GO:0045995=PMID:7693131, GO:0003007=PMID:7693131, GO:0016020=PMID:8452530, GO:0071363=GO_REF:0000019, GO:0005901=PMID:15182363, GO:0031017=GO_REF:0000019, GO:0001934=PMID:7556070, GO:0004713=PMID:8496180, GO:0043410=PMID:11500939, GO:0004716=PMID:6849137} P06213 Insulin receptor protein 20130413 {GO:0005515=IPI, GO:0005159=IDA, GO:0043560=IPI, GO:0046777=IDA, GO:0005899=IMP, GO:0046326=NAS, GO:0045821=IMP, GO:0042169=IPI, GO:0043559=IPI, GO:0023014=IDA, GO:0032869=IDA, GO:0030335=IMP, GO:0005975=IEA, GO:0045740=IMP, GO:0018108=IDA, GO:0045840=IMP, GO:0007186=IDA, GO:0005887=IDA, GO:0048639=IMP, GO:0010008=TAS, GO:0043548=IPI, GO:0008286=IDA, GO:0051897=IMP, GO:0008284=IC, GO:0005886=IC, GO:0031994=IPI, GO:0051425=IPI, GO:0031995=IPI, GO:0051290=IDA, GO:0060267=IDA, GO:0045429=IMP, GO:0032147=IMP, GO:0000187=IMP, GO:0030238=IEA, GO:0032148=IDA, GO:0019087=IMP, GO:0006355=IMP, GO:0005009=IDA, GO:0045725=IDA, GO:0042593=IMP, GO:0005525=IDA, GO:0005524=IDA, GO:0045995=IMP, GO:0003007=IMP, GO:0016020=IDA, GO:0071363=IEA, GO:0005901=IDA, GO:0031017=IEA, GO:0001934=IDA, GO:0004713=IDA, GO:0043410=IMP, GO:0004716=IDA} G-protein coupled receptor signaling pathway, activation of MAPK activity, activation of protein kinase B activity, activation of protein kinase activity, carbohydrate metabolic process, cellular response to growth factor stimulus, cellular response to insulin stimulus, exocrine pancreas development, glucose homeostasis, heart morphogenesis, insulin receptor signaling pathway, male sex determination, peptidyl-tyrosine phosphorylation, positive regulation of DNA replication, positive regulation of MAPK cascade, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of developmental growth, positive regulation of glucose import, positive regulation of glycogen biosynthetic process, positive regulation of glycolysis, positive regulation of mitosis, positive regulation of nitric oxide biosynthetic process, positive regulation of protein kinase B signaling cascade, positive regulation of protein phosphorylation, positive regulation of respiratory burst, protein autophosphorylation, protein heterotetramerization, regulation of embryonic development, regulation of transcription, DNA-dependent, signal transduction by phosphorylation, transformation of host cell by virus caveola, endosome membrane, insulin receptor complex, integral to plasma membrane, membrane, plasma membrane ATP binding, GTP binding, PTB domain binding, SH2 domain binding, insulin binding, insulin receptor substrate binding, insulin-activated receptor activity, insulin-like growth factor I binding, insulin-like growth factor II binding, insulin-like growth factor receptor binding, phosphatidylinositol 3-kinase binding, protein binding, protein tyrosine kinase activity, receptor signaling protein tyrosine kinase activity Human INSRR UniProtKB UniProtKB {GO:0046777=PMID:21641549, GO:0031532=PMID:21641549, GO:0005887=PMID:10226785, GO:0030238=GO_REF:0000019, GO:0043560=GO_REF:0000002, GO:0004714=PMID:21641549, GO:0071469=PMID:21641549, GO:0007169=PMID:10226785, GO:0005524=GO_REF:0000037, GO:0043548=GO_REF:0000002} P14616 Insulin receptor-related protein protein 20110920 {GO:0046777=IMP, GO:0031532=IDA, GO:0005887=NAS, GO:0030238=IEA, GO:0043560=IEA, GO:0004714=IDA, GO:0071469=IDA, GO:0007169=NAS, GO:0005524=IEA, GO:0043548=IEA} actin cytoskeleton reorganization, cellular response to alkalinity, male sex determination, protein autophosphorylation, transmembrane receptor protein tyrosine kinase signaling pathway integral to plasma membrane ATP binding, insulin receptor substrate binding, phosphatidylinositol 3-kinase binding, transmembrane receptor protein tyrosine kinase activity Human INTS1 HGNC UniProtKB {GO:0034474=GO_REF:0000019, GO:0031965=GO_REF:0000039, GO:0043066=GO_REF:0000019, GO:0001833=GO_REF:0000019, GO:0032039=PMID:16239144, GO:0016021=GO_REF:0000037, GO:0043154=GO_REF:0000019, GO:0016180=PMID:16239144} Q8N201 Integrator complex subunit 1 protein 20090723 {GO:0034474=IEA, GO:0031965=IEA, GO:0043066=IEA, GO:0001833=IEA, GO:0032039=IDA, GO:0016021=IEA, GO:0043154=IEA, GO:0016180=IDA} U2 snRNA 3'-end processing, inner cell mass cell proliferation, negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, snRNA processing integral to membrane, integrator complex, nuclear membrane Human INTS10 HPA UniProtKB {GO:0005515=PMID:16239144, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0032039=PMID:16239144, GO:0005634=GO_REF:0000052, GO:0016180=PMID:16239144} Q9NVR2 Integrator complex subunit 10 protein 20110516 {GO:0005515=IPI, GO:0005737=IDA, GO:0005730=IDA, GO:0032039=IDA, GO:0005634=IDA, GO:0016180=IDA} snRNA processing cytoplasm, integrator complex, nucleolus, nucleus protein binding Human INTS12 HGNC UniProtKB {GO:0005515=PMID:16239144, GO:0032039=PMID:16239144, GO:0008270=GO_REF:0000002, GO:0016180=PMID:16239144} Q96CB8 Integrator complex subunit 12 protein 20060426 {GO:0005515=IPI, GO:0032039=IDA, GO:0008270=IEA, GO:0016180=IDA} snRNA processing integrator complex protein binding, zinc ion binding Human INTS2 LIFEdb UniProtKB {GO:0005622=GO_REF:0000054, GO:0005515=PMID:16239144, GO:0031965=GO_REF:0000039, GO:0032039=PMID:16239144, GO:0016021=GO_REF:0000037, GO:0016180=PMID:16239144} Q9H0H0 Integrator complex subunit 2 protein 20100607 {GO:0005622=IDA, GO:0005515=IPI, GO:0031965=IEA, GO:0032039=IDA, GO:0016021=IEA, GO:0016180=IDA} snRNA processing integral to membrane, integrator complex, intracellular, nuclear membrane protein binding Human INTS3 HGNC UniProtKB {GO:0005515=PMID:16239144, GO:0006281=PMID:19605351, GO:0010212=PMID:19605351, GO:0032039=PMID:16239144, GO:0000075=PMID:19683501, GO:0070876=PMID:19683501, GO:0005634=PMID:19683501, GO:0006974=PMID:19683501, GO:0016180=PMID:16239144} Q68E01 Integrator complex subunit 3 protein 20061120 {GO:0005515=IPI, GO:0006281=IMP, GO:0010212=IMP, GO:0032039=IDA, GO:0000075=IMP, GO:0070876=IDA, GO:0005634=IDA, GO:0006974=IMP, GO:0016180=IDA} DNA repair, cell cycle checkpoint, response to DNA damage stimulus, response to ionizing radiation, snRNA processing SOSS complex, integrator complex, nucleus protein binding Human INTS4 HGNC UniProtKB {GO:0005515=PMID:16239144, GO:0032039=PMID:16239144, GO:0016180=PMID:16239144} Q96HW7 Integrator complex subunit 4 protein 20061127 {GO:0005515=IPI, GO:0032039=IDA, GO:0016180=IDA} snRNA processing integrator complex protein binding Human INTS5 HGNC UniProtKB {GO:0005515=PMID:16239144, GO:0032039=PMID:16239144, GO:0016021=GO_REF:0000037, GO:0016180=PMID:16239144} Q6P9B9 Integrator complex subunit 5 protein 20061117 {GO:0005515=IPI, GO:0032039=IDA, GO:0016021=IEA, GO:0016180=IDA} snRNA processing integral to membrane, integrator complex protein binding Human INTS6 HPA UniProtKB {GO:0005515=PMID:16239144, GO:0032039=PMID:16239144, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0015629=GO_REF:0000052, GO:0016180=PMID:16239144, GO:0004888=PMID:10467397} Q9UL03 Integrator complex subunit 6 protein 20080205 {GO:0005515=IPI, GO:0032039=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0015629=IDA, GO:0016180=IDA, GO:0004888=TAS} snRNA processing actin cytoskeleton, integrator complex, nucleolus, nucleus protein binding, transmembrane signaling receptor activity Human INTS7 HGNC UniProtKB {GO:0005515=PMID:21659603, GO:0005694=PMID:21659603, GO:0032039=PMID:16239144, GO:0000077=PMID:21659603, GO:0071479=PMID:21659603, GO:0016180=PMID:16239144} Q9NVH2 Integrator complex subunit 7 protein 20061120 {GO:0005515=IPI, GO:0005694=IDA, GO:0032039=IDA, GO:0000077=IMP, GO:0071479=IDA, GO:0016180=IDA} DNA damage checkpoint, cellular response to ionizing radiation, snRNA processing chromosome, integrator complex protein binding Human INTS8 HGNC UniProtKB {GO:0005515=PMID:16239144, GO:0032039=PMID:16239144, GO:0016180=PMID:16239144} Q75QN2 Integrator complex subunit 8 protein 20061117 {GO:0005515=IPI, GO:0032039=IDA, GO:0016180=IDA} snRNA processing integrator complex protein binding Human INTS9 HGNC UniProtKB {GO:0005515=PMID:16239144, GO:0016787=GO_REF:0000002, GO:0032039=PMID:16239144, GO:0016180=PMID:16239144} Q9NV88 Integrator complex subunit 9 protein 20061106 {GO:0005515=IPI, GO:0016787=IEA, GO:0032039=IDA, GO:0016180=IDA} snRNA processing integrator complex hydrolase activity, protein binding Human INVS UniProtKB UniProtKB {GO:0005515=PMID:21565611, GO:0005516=GO_REF:0000037, GO:0001822=GO_REF:0000019, GO:0005874=GO_REF:0000037, GO:0005819=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0009791=GO_REF:0000019, GO:0005929=GO_REF:0000039, GO:0005737=GO_REF:0000039, GO:0031016=GO_REF:0000019, GO:0016020=GO_REF:0000039, GO:0060971=GO_REF:0000019, GO:0016055=GO_REF:0000037, GO:0090090=PMID:18371931} Q9Y283 Inversin protein 20110616 {GO:0005515=IPI, GO:0005516=IEA, GO:0001822=IEA, GO:0005874=IEA, GO:0005819=IEA, GO:0005634=IEA, GO:0009791=IEA, GO:0005929=IEA, GO:0005737=IEA, GO:0031016=IEA, GO:0016020=IEA, GO:0060971=IEA, GO:0016055=IEA, GO:0090090=IDA} Wnt receptor signaling pathway, embryonic heart tube left/right pattern formation, kidney development, negative regulation of canonical Wnt receptor signaling pathway, pancreas development, post-embryonic development cilium, cytoplasm, membrane, microtubule, nucleus, spindle calmodulin binding, protein binding Human UniProtKB:Q15051 IP6K1 HPA UniProtKB {GO:0046854=PMID:10574768, GO:0008440=GO_REF:0000002, GO:0043647=Reactome:REACT_150275, GO:0005730=GO_REF:0000052, GO:0052724=GO_REF:0000003, GO:0005654=Reactome:REACT_150465, GO:0052723=GO_REF:0000003, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0000832=GO_REF:0000003, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_150450} Q92551 Inositol hexakisphosphate kinase 1 protein 20111111 {GO:0046854=IDA, GO:0008440=IEA, GO:0043647=TAS, GO:0005730=IDA, GO:0052724=IEA, GO:0005654=TAS, GO:0052723=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0000832=IEA, GO:0005524=IEA, GO:0005829=TAS} inositol phosphate metabolic process, phosphatidylinositol phosphorylation, small molecule metabolic process cytosol, nucleolus, nucleoplasm, nucleus ATP binding, inositol hexakisphosphate 1-kinase activity, inositol hexakisphosphate 3-kinase activity, inositol hexakisphosphate 5-kinase activity, inositol-1,4,5-trisphosphate 3-kinase activity Human IP6K2 HPA UniProtKB {GO:0008440=GO_REF:0000002, GO:0030308=PMID:11337497, GO:0043065=PMID:11337497, GO:0043647=Reactome:REACT_150275, GO:0019221=Reactome:REACT_25229, GO:0052724=GO_REF:0000003, GO:0005634=GO_REF:0000052, GO:0052723=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0000832=GO_REF:0000003, GO:0043231=GO_REF:0000052, GO:0046854=PMID:10574768, GO:0060337=Reactome:REACT_25162, GO:0006817=GO_REF:0000019, GO:0005654=Reactome:REACT_150465, GO:0045111=GO_REF:0000052} Q9UHH9 Inositol hexakisphosphate kinase 2 protein 20101115 {GO:0008440=IEA, GO:0030308=IMP, GO:0043065=IMP, GO:0043647=TAS, GO:0019221=TAS, GO:0052724=IEA, GO:0005634=IDA, GO:0052723=IEA, GO:0044281=TAS, GO:0005524=IEA, GO:0000832=IEA, GO:0043231=IDA, GO:0046854=IDA, GO:0060337=TAS, GO:0006817=IEA, GO:0005654=TAS, GO:0045111=IDA} cytokine-mediated signaling pathway, inositol phosphate metabolic process, negative regulation of cell growth, phosphate ion transport, phosphatidylinositol phosphorylation, positive regulation of apoptotic process, small molecule metabolic process, type I interferon-mediated signaling pathway intermediate filament cytoskeleton, intracellular membrane-bounded organelle, nucleoplasm, nucleus ATP binding, inositol hexakisphosphate 1-kinase activity, inositol hexakisphosphate 3-kinase activity, inositol hexakisphosphate 5-kinase activity, inositol-1,4,5-trisphosphate 3-kinase activity Human IPCEF1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0004601=PMID:11320098, GO:0005543=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0005344=PMID:11919282, GO:0006979=PMID:11320098, GO:0015671=PMID:11919282} Q8WWN9 Interactor protein for cytohesin exchange factors 1 protein 20041006 {GO:0005737=IEA, GO:0004601=ISS, GO:0005543=IEA, GO:0005886=IEA, GO:0005344=NAS, GO:0006979=ISS, GO:0015671=NAS} oxygen transport, response to oxidative stress cytoplasm, plasma membrane oxygen transporter activity, peroxidase activity, phospholipid binding Human UniProtKB:Q921A4 IPMK HPA UniProtKB {GO:0000824=GO_REF:0000019, GO:0008440=GO_REF:0000019, GO:0043647=Reactome:REACT_150275, GO:0032958=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005654=Reactome:REACT_150392, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0000823=GO_REF:0000003, GO:0001841=GO_REF:0000019} Q8NFU5 Inositol polyphosphate multikinase protein 20110516 {GO:0000824=IEA, GO:0008440=IEA, GO:0043647=TAS, GO:0032958=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005654=TAS, GO:0044281=TAS, GO:0005524=IEA, GO:0000823=IEA, GO:0001841=IEA} inositol phosphate biosynthetic process, inositol phosphate metabolic process, neural tube formation, small molecule metabolic process nucleolus, nucleoplasm, nucleus ATP binding, inositol tetrakisphosphate 3-kinase activity, inositol-1,4,5-trisphosphate 3-kinase activity, inositol-1,4,5-trisphosphate 6-kinase activity NOT Human IPO11 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0006610=GO_REF:0000019, GO:0005643=GO_REF:0000002, GO:0008565=GO_REF:0000019, GO:0006886=GO_REF:0000002} Q9UI26 Importin-11 protein 20130413 {GO:0005737=IEA, GO:0006610=IEA, GO:0005643=IEA, GO:0008565=IEA, GO:0006886=IEA} intracellular protein transport, ribosomal protein import into nucleus cytoplasm, nuclear pore protein transporter activity Human UniProtKB-SubCell:SL-0086 IPO13 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0005737=GO_REF:0000039, GO:0005643=GO_REF:0000002, GO:0008565=GO_REF:0000002, GO:0006606=PMID:15964792} O94829 Importin-13 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0005643=IEA, GO:0008565=IEA, GO:0006606=IDA} protein import into nucleus cytoplasm, nuclear pore protein binding, protein transporter activity Human UniProtKB:Q15699 IPO4 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005643=PMID:11823430, GO:0008565=GO_REF:0000002, GO:0015031=PMID:11823430, GO:0006886=GO_REF:0000002} Q8TEX9 Importin-4 protein 20050920 {GO:0005737=IEA, GO:0005643=NAS, GO:0008565=IEA, GO:0015031=NAS, GO:0006886=IEA} intracellular protein transport, protein transport cytoplasm, nuclear pore protein transporter activity colocalizes_with Human IPO5 IntAct UniProtKB {GO:0005515=PMID:20562859, GO:0005737=GO_REF:0000039, GO:0006610=PMID:9687515, GO:0005643=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0008536=PMID:9114010, GO:0008565=GO_REF:0000024, GO:0005730=GO_REF:0000039, GO:0005634=GO_REF:0000024, GO:0005095=PMID:9271386, GO:0006607=GO_REF:0000024, GO:0006886=GO_REF:0000002} O00410 Importin-5 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0006610=IDA, GO:0005643=IEA, GO:0019048=IEA, GO:0008536=TAS, GO:0008565=ISS, GO:0005730=IEA, GO:0005634=ISS, GO:0005095=TAS, GO:0006607=ISS, GO:0006886=IEA} NLS-bearing substrate import into nucleus, intracellular protein transport, ribosomal protein import into nucleus, virus-host interaction cytoplasm, nuclear pore, nucleolus, nucleus GTPase inhibitor activity, Ran GTPase binding, protein binding, protein transporter activity Human UniProtKB:Q9H0R8 IPO7 HPA UniProtKB {GO:0005515=PMID:15282309, GO:0005215=PMID:9214382, GO:0007165=PMID:9214382, GO:0042393=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0005083=PMID:9214382, GO:0005794=GO_REF:0000052, GO:0005643=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0008536=PMID:9214382, GO:0008565=GO_REF:0000002, GO:0006606=GO_REF:0000019} O95373 Importin-7 protein 20100326 {GO:0005515=IPI, GO:0005215=TAS, GO:0007165=TAS, GO:0042393=IEA, GO:0005737=IDA, GO:0005083=TAS, GO:0005794=IDA, GO:0005643=IEA, GO:0019048=IEA, GO:0008536=TAS, GO:0008565=IEA, GO:0006606=IEA} protein import into nucleus, signal transduction, virus-host interaction Golgi apparatus, cytoplasm, nuclear pore Ran GTPase binding, histone binding, protein binding, protein transporter activity, small GTPase regulator activity, transporter activity Human IPO8 IntAct UniProtKB {GO:0005515=PMID:19167051, GO:0007165=PMID:9214382, GO:0005737=GO_REF:0000039, GO:0005643=GO_REF:0000002, GO:0008536=PMID:9214382, GO:0008565=GO_REF:0000002, GO:0006886=GO_REF:0000002} O15397 Importin-8 protein 20130415 {GO:0005515=IPI, GO:0007165=TAS, GO:0005737=IEA, GO:0005643=IEA, GO:0008536=TAS, GO:0008565=IEA, GO:0006886=IEA} intracellular protein transport, signal transduction cytoplasm, nuclear pore Ran GTPase binding, protein binding, protein transporter activity Human UniProtKB:Q9UL18 IPO9 UniProtKB UniProtKB {GO:0005515=PMID:15282309, GO:0042393=GO_REF:0000024, GO:0005737=PMID:11823430, GO:0005643=GO_REF:0000002, GO:0008565=PMID:11823430, GO:0006606=PMID:11823430} Q96P70 Importin-9 protein 20061113 {GO:0005515=IPI, GO:0042393=ISS, GO:0005737=IDA, GO:0005643=IEA, GO:0008565=IDA, GO:0006606=NAS} protein import into nucleus cytoplasm, nuclear pore histone binding, protein binding, protein transporter activity Human UniProtKB:Q9BUP3 IPP PINC UniProtKB {GO:0005737=GO_REF:0000037, GO:0003779=GO_REF:0000037, GO:0015629=PMID:10072760} Q9Y573 Actin-binding protein IPP protein 20030904 {GO:0005737=IEA, GO:0003779=IEA, GO:0015629=TAS} actin cytoskeleton, cytoplasm actin binding Human IPPK BHF-UCL UniProtKB {GO:0005622=PMID:12084730, GO:0052746=PMID:12084730, GO:0043647=Reactome:REACT_150275, GO:0005654=Reactome:REACT_150383, GO:0044281=Reactome:REACT_111217, GO:0035299=PMID:12084730, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_150360} Q9H8X2 Inositol-pentakisphosphate 2-kinase protein 20111106 {GO:0005622=IDA, GO:0052746=IDA, GO:0043647=TAS, GO:0005654=TAS, GO:0044281=TAS, GO:0035299=IDA, GO:0005524=IEA, GO:0005829=TAS} inositol phosphate metabolic process, inositol phosphorylation, small molecule metabolic process cytosol, intracellular, nucleoplasm ATP binding, inositol pentakisphosphate 2-kinase activity Human IQCA1 UniProtKB UniProtKB {GO:0005524=GO_REF:0000037} Q86XH1 IQ and AAA domain-containing protein 1 protein 20130413 {GO:0005524=IEA} ATP binding Human UniProtKB-KW:KW-0067 IQCB1 HGNC UniProtKB {GO:0005515=PMID:21565611, GO:0005516=PMID:15723066, GO:0042384=GO_REF:0000024, GO:0005813=PMID:21399614, GO:0005737=GO_REF:0000037, GO:0032391=PMID:15723066, GO:0045494=PMID:15723066, GO:0048496=PMID:15723066, GO:0001750=GO_REF:0000019} Q15051 IQ calmodulin-binding motif-containing protein 1 protein 20071018 {GO:0005515=IPI, GO:0005516=IDA, GO:0042384=ISS, GO:0005813=IDA, GO:0005737=IEA, GO:0032391=IDA, GO:0045494=IMP, GO:0048496=IMP, GO:0001750=IEA} cilium assembly, maintenance of organ identity, photoreceptor cell maintenance centrosome, cytoplasm, photoreceptor connecting cilium, photoreceptor outer segment calmodulin binding, protein binding Human IQCG null null {} null null null null {} null null null IQCH null null {} null null null null {} null null null IQCJ null null {} null null null null {} null null null IQCK null null {} null null null null {} null null null IQGAP1 GOC UniProtKB {GO:0005515=PMID:21724847, GO:0043005=GO_REF:0000019, GO:0030054=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0072015=GO_REF:0000024, GO:0007264=GO_REF:0000002, GO:0005884=PMID:8670801, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0032403=GO_REF:0000019, GO:0001817=GO_REF:0000019, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0005911=GO_REF:0000019, GO:0045860=GO_REF:0000019, GO:0071277=PMID:18567582, GO:0031252=GO_REF:0000019, GO:0019901=PMID:17563371, GO:0035305=GO_REF:0000019, GO:0019903=PMID:16380380, GO:0005509=PMID:18567582, GO:0005874=PMID:21525035, GO:0005730=GO_REF:0000052, GO:0030496=PMID:15166316, GO:0016328=GO_REF:0000019, GO:0043547=PMID:8051149, GO:0005099=GO_REF:0000002, GO:0043234=GO_REF:0000019, GO:0007165=PMID:8051149, GO:0048365=GO_REF:0000019, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0030529=GO_REF:0000019, GO:0036057=GO_REF:0000024, GO:0005095=PMID:8670801, GO:0005096=PMID:8051149} P46940 Ras GTPase-activating-like protein IQGAP1 protein 20130413 {GO:0005515=IPI, GO:0043005=IEA, GO:0030054=IDA, GO:0005886=IDA, GO:0072015=ISS, GO:0007264=IEA, GO:0005884=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0032403=IEA, GO:0001817=IEA, GO:0005622=IEA, GO:0005737=IDA, GO:0005911=IEA, GO:0045860=IEA, GO:0071277=IDA, GO:0031252=IEA, GO:0019901=IPI, GO:0035305=IEA, GO:0019903=IPI, GO:0005509=TAS, GO:0005874=IDA, GO:0005730=IDA, GO:0030496=IDA, GO:0016328=IEA, GO:0043547=TAS, GO:0005099=IEA, GO:0043234=IEA, GO:0007165=TAS, GO:0048365=IEA, GO:0006112=TAS, GO:0050796=TAS, GO:0030529=IEA, GO:0036057=ISS, GO:0005095=TAS, GO:0005096=TAS} cellular response to calcium ion, energy reserve metabolic process, glomerular visceral epithelial cell development, negative regulation of dephosphorylation, positive regulation of GTPase activity, positive regulation of protein kinase activity, regulation of cytokine production, regulation of insulin secretion, signal transduction, small GTPase mediated signal transduction, small molecule metabolic process actin filament, cell junction, cell leading edge, cell-cell junction, cytoplasm, intracellular, lateral plasma membrane, microtubule, midbody, neuron projection, nucleolus, nucleus, plasma membrane, protein complex, ribonucleoprotein complex, slit diaphragm GTPase activator activity, GTPase inhibitor activity, Rac GTPase binding, Ras GTPase activator activity, calcium ion binding, protein binding, protein complex binding, protein kinase binding, protein phosphatase binding Human IQGAP2 PINC UniProtKB {GO:0005622=GO_REF:0000002, GO:0005099=GO_REF:0000002, GO:0005516=GO_REF:0000037, GO:0051056=GO_REF:0000002, GO:0007165=PMID:8756646, GO:0005902=GO_REF:0000019, GO:0007264=GO_REF:0000002, GO:0003779=PMID:8756646, GO:0015629=PMID:8756646, GO:0005095=PMID:8756646, GO:0005096=GO_REF:0000002} Q13576 Ras GTPase-activating-like protein IQGAP2 protein 20030904 {GO:0005622=IEA, GO:0005099=IEA, GO:0005516=IEA, GO:0051056=IEA, GO:0007165=TAS, GO:0005902=IEA, GO:0007264=IEA, GO:0003779=TAS, GO:0015629=TAS, GO:0005095=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction actin cytoskeleton, intracellular, microvillus GTPase activator activity, GTPase inhibitor activity, Ras GTPase activator activity, actin binding, calmodulin binding Human IQGAP3 ENSEMBL UniProtKB {GO:0005516=GO_REF:0000037, GO:0008361=GO_REF:0000019, GO:0071310=GO_REF:0000019, GO:0007265=GO_REF:0000019, GO:0016328=GO_REF:0000019, GO:0005099=GO_REF:0000002, GO:0010628=GO_REF:0000019, GO:0000187=GO_REF:0000019, GO:0000082=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0005911=GO_REF:0000019, GO:0010629=GO_REF:0000019, GO:0017048=GO_REF:0000019, GO:0070371=GO_REF:0000019, GO:0033601=GO_REF:0000019} Q86VI3 Ras GTPase-activating-like protein IQGAP3 protein 20130413 {GO:0005516=IEA, GO:0008361=IEA, GO:0071310=IEA, GO:0007265=IEA, GO:0016328=IEA, GO:0005099=IEA, GO:0010628=IEA, GO:0000187=IEA, GO:0000082=IEA, GO:0005737=IEA, GO:0005911=IEA, GO:0010629=IEA, GO:0017048=IEA, GO:0070371=IEA, GO:0033601=IEA} ERK1 and ERK2 cascade, G1/S transition of mitotic cell cycle, Ras protein signal transduction, activation of MAPK activity, cellular response to organic substance, negative regulation of gene expression, positive regulation of gene expression, positive regulation of mammary gland epithelial cell proliferation, regulation of cell size cell-cell junction, cytoplasm, lateral plasma membrane Ras GTPase activator activity, Rho GTPase binding, calmodulin binding Human Ensembl:ENSMUSP00000071715 IQSEC1 HPA UniProtKB {GO:0005802=GO_REF:0000033, GO:0005086=GO_REF:0000033, GO:0005737=GO_REF:0000039, GO:0030036=GO_REF:0000033, GO:0030054=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0032012=GO_REF:0000002, GO:0016192=GO_REF:0000033, GO:0043231=GO_REF:0000052} Q6DN90 IQ motif and SEC7 domain-containing protein 1 protein 20110516 {GO:0005802=IBA, GO:0005086=IBA, GO:0005737=IEA, GO:0030036=IBA, GO:0030054=IDA, GO:0005543=IEA, GO:0005730=IDA, GO:0032012=IEA, GO:0016192=IBA, GO:0043231=IDA} actin cytoskeleton organization, regulation of ARF protein signal transduction, vesicle-mediated transport cell junction, cytoplasm, intracellular membrane-bounded organelle, nucleolus, trans-Golgi network ARF guanyl-nucleotide exchange factor activity, phospholipid binding Human IQSEC2 RefGenome UniProtKB {GO:0005802=GO_REF:0000033, GO:0005086=GO_REF:0000033, GO:0005737=GO_REF:0000039, GO:0030054=GO_REF:0000033, GO:0030036=GO_REF:0000033, GO:0005543=GO_REF:0000002, GO:0032012=GO_REF:0000002, GO:0005634=GO_REF:0000033, GO:0016192=GO_REF:0000033} Q5JU85 IQ motif and SEC7 domain-containing protein 2 protein 20120409 {GO:0005802=IBA, GO:0005086=IBA, GO:0005737=IEA, GO:0030054=IBA, GO:0030036=IBA, GO:0005543=IEA, GO:0032012=IEA, GO:0005634=IBA, GO:0016192=IBA} actin cytoskeleton organization, regulation of ARF protein signal transduction, vesicle-mediated transport cell junction, cytoplasm, nucleus, trans-Golgi network ARF guanyl-nucleotide exchange factor activity, phospholipid binding Human PANTHER:PTN000070822 IQUB ENSEMBL UniProtKB {GO:0001669=GO_REF:0000019, GO:0060271=GO_REF:0000019} Q8NA54 IQ and ubiquitin-like domain-containing protein protein 20130413 {GO:0001669=IEA, GO:0060271=IEA} cilium morphogenesis acrosomal vesicle Human Ensembl:ENSMUSP00000051177 IRAK1 GOC UniProtKB {GO:0005515=PMID:22037600, GO:0004842=Reactome:REACT_22381, GO:0051259=PMID:16831874, GO:0051403=Reactome:REACT_21308, GO:0042803=PMID:10383454, GO:0002756=Reactome:REACT_6809, GO:0004704=PMID:8599092, GO:0046777=PMID:10383454, GO:0016301=PMID:12054681, GO:0002755=PMID:10383454, GO:0032496=PMID:10383454, GO:0007178=PMID:11397809, GO:0043123=Reactome:REACT_24918, GO:0031663=PMID:10383454, GO:0016772=GO_REF:0000002, GO:0005811=GO_REF:0000024, GO:0038124=Reactome:REACT_8006, GO:0046982=PMID:10383454, GO:0038123=Reactome:REACT_8005, GO:0034134=PMID:10383454, GO:0002224=Reactome:REACT_9020, GO:0001959=PMID:10383454, GO:0045087=Reactome:REACT_6802, GO:0034166=Reactome:REACT_9027, GO:0035666=Reactome:REACT_25281, GO:0045893=PMID:11397809, GO:0010008=Reactome:REACT_25312, GO:0034162=Reactome:REACT_9047, GO:0016567=Reactome:REACT_22381, GO:0034142=Reactome:REACT_6894, GO:0005886=Reactome:REACT_27228, GO:0070423=Reactome:REACT_75776, GO:0005634=GO_REF:0000039, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_27140, GO:0000187=Reactome:REACT_21399, GO:0045323=PMID:10854325, GO:0051092=PMID:10383454, GO:0045944=GO_REF:0000019, GO:0034138=Reactome:REACT_6783, GO:0070498=PMID:10383454, GO:0070555=PMID:10383454, GO:0048011=Reactome:REACT_13776, GO:0005149=GO_REF:0000019, GO:0043066=Reactome:REACT_13537, GO:0007250=PMID:11397809, GO:0007254=Reactome:REACT_21368, GO:0071456=GO_REF:0000019, GO:0032088=PMID:10383454, GO:0005524=GO_REF:0000037, GO:0048661=GO_REF:0000019, GO:0007165=PMID:10854325, GO:0004672=Reactome:REACT_27151, GO:0004674=Reactome:REACT_25184, GO:0006468=PMID:8599092, GO:0032494=GO_REF:0000019, GO:0034146=Reactome:REACT_9061} P51617 Interleukin-1 receptor-associated kinase 1 protein 20130413 {GO:0005515=IPI, GO:0004842=TAS, GO:0051259=IMP, GO:0051403=TAS, GO:0042803=IPI, GO:0002756=TAS, GO:0004704=TAS, GO:0046777=IDA, GO:0016301=IDA, GO:0002755=TAS, GO:0032496=IMP, GO:0007178=NAS, GO:0043123=TAS, GO:0031663=IMP, GO:0016772=IEA, GO:0005811=ISS, GO:0038124=TAS, GO:0046982=IPI, GO:0038123=TAS, GO:0034134=IMP, GO:0002224=TAS, GO:0001959=IMP, GO:0045087=TAS, GO:0034166=TAS, GO:0035666=TAS, GO:0045893=NAS, GO:0010008=TAS, GO:0034162=TAS, GO:0016567=TAS, GO:0034142=TAS, GO:0005886=TAS, GO:0070423=TAS, GO:0005634=IEA, GO:0035872=TAS, GO:0005829=TAS, GO:0000187=TAS, GO:0045323=NAS, GO:0051092=IDA, GO:0045944=IEA, GO:0034138=TAS, GO:0070498=IMP, GO:0070555=IMP, GO:0048011=TAS, GO:0005149=IEA, GO:0043066=TAS, GO:0007250=IDA, GO:0007254=TAS, GO:0071456=IEA, GO:0032088=IMP, GO:0005524=IEA, GO:0048661=IEA, GO:0007165=NAS, GO:0004672=TAS, GO:0004674=EXP, GO:0006468=TAS, GO:0032494=IEA, GO:0034146=TAS} JNK cascade, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, activation of MAPK activity, activation of NF-kappaB-inducing kinase activity, cellular response to hypoxia, innate immune response, interleukin-1-mediated signaling pathway, lipopolysaccharide-mediated signaling pathway, negative regulation of NF-kappaB transcription factor activity, negative regulation of apoptotic process, neurotrophin TRK receptor signaling pathway, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, nucleotide-binding oligomerization domain containing signaling pathway, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of smooth muscle cell proliferation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein autophosphorylation, protein oligomerization, protein phosphorylation, protein ubiquitination, regulation of cytokine-mediated signaling pathway, response to interleukin-1, response to lipopolysaccharide, response to peptidoglycan, signal transduction, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, transmembrane receptor protein serine/threonine kinase signaling pathway cytosol, endosome membrane, interleukin-1 receptor complex, lipid particle, nucleus, plasma membrane ATP binding, NF-kappaB-inducing kinase activity, interleukin-1 receptor binding, kinase activity, protein binding, protein heterodimerization activity, protein homodimerization activity, protein kinase activity, protein serine/threonine kinase activity, transferase activity, transferring phosphorus-containing groups, ubiquitin-protein ligase activity Human IRAK1BP1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0006355=GO_REF:0000037, GO:0007249=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q5VVH5 Interleukin-1 receptor-associated kinase 1-binding protein 1 protein 20051209 {GO:0005737=IEA, GO:0006355=IEA, GO:0007249=ISS, GO:0005634=IEA, GO:0006351=IEA} I-kappaB kinase/NF-kappaB cascade, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus Human UniProtKB:Q9ESJ7 IRAK2 BHF-UCL UniProtKB {GO:0005515=PMID:21988832, GO:0034142=Reactome:REACT_6894, GO:0005886=Reactome:REACT_121298, GO:0070423=Reactome:REACT_75776, GO:0007249=PMID:9374458, GO:0051403=Reactome:REACT_21308, GO:0042803=PMID:10383454, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_27140, GO:0002756=Reactome:REACT_6809, GO:0000187=Reactome:REACT_21399, GO:0051092=PMID:10383454, GO:0006954=PMID:9374458, GO:0002755=PMID:10383454, GO:0031663=GO_REF:0000019, GO:0034138=Reactome:REACT_6783, GO:0070498=PMID:10383454, GO:0070555=PMID:10383454, GO:0038124=Reactome:REACT_8006, GO:0046982=PMID:10383454, GO:0009986=PMID:12493773, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0007254=Reactome:REACT_21368, GO:0032088=PMID:10383454, GO:0002224=Reactome:REACT_9020, GO:0005524=GO_REF:0000037, GO:0001959=PMID:10383454, GO:0004672=GO_REF:0000002, GO:0045087=Reactome:REACT_6802, GO:0034166=Reactome:REACT_9027, GO:0035666=Reactome:REACT_25281, GO:0006468=PMID:9374458, GO:0034146=Reactome:REACT_9061, GO:0010008=Reactome:REACT_25322, GO:0034162=Reactome:REACT_9047} O43187 Interleukin-1 receptor-associated kinase-like 2 protein 20090424 {GO:0005515=IPI, GO:0034142=TAS, GO:0005886=TAS, GO:0070423=TAS, GO:0007249=TAS, GO:0051403=TAS, GO:0042803=IPI, GO:0035872=TAS, GO:0005829=TAS, GO:0002756=TAS, GO:0000187=TAS, GO:0051092=IMP, GO:0006954=TAS, GO:0002755=TAS, GO:0031663=IEA, GO:0034138=TAS, GO:0070498=IMP, GO:0070555=IMP, GO:0038124=TAS, GO:0046982=IPI, GO:0009986=IDA, GO:0038123=TAS, GO:0034134=TAS, GO:0007254=TAS, GO:0032088=IMP, GO:0002224=TAS, GO:0005524=IEA, GO:0001959=IMP, GO:0004672=IEA, GO:0045087=TAS, GO:0034166=TAS, GO:0035666=TAS, GO:0006468=TAS, GO:0034146=TAS, GO:0010008=TAS, GO:0034162=TAS} I-kappaB kinase/NF-kappaB cascade, JNK cascade, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, activation of MAPK activity, inflammatory response, innate immune response, interleukin-1-mediated signaling pathway, lipopolysaccharide-mediated signaling pathway, negative regulation of NF-kappaB transcription factor activity, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, nucleotide-binding oligomerization domain containing signaling pathway, positive regulation of NF-kappaB transcription factor activity, protein phosphorylation, regulation of cytokine-mediated signaling pathway, response to interleukin-1, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway cell surface, cytosol, endosome membrane, plasma membrane ATP binding, protein binding, protein heterodimerization activity, protein homodimerization activity, protein kinase activity Human IRAK3 BHF-UCL UniProtKB {GO:0005515=PMID:21903422, GO:0034122=PMID:12150927, GO:0032715=PMID:12150927, GO:0019221=GO_REF:0000024, GO:0005634=PMID:17379480, GO:0042803=PMID:10383454, GO:0005737=PMID:17379480, GO:0051092=PMID:10383454, GO:0046777=GO_REF:0000019, GO:0001960=PMID:12150927, GO:0043244=GO_REF:0000024, GO:0002755=PMID:10383454, GO:0043407=PMID:17379480, GO:0032496=PMID:12150927, GO:0070555=PMID:10383454, GO:0070498=PMID:10383454, GO:0045824=PMID:12150927, GO:0000287=PMID:10383454, GO:0046982=PMID:10383454, GO:0042177=PMID:17379480, GO:0032720=PMID:15728517, GO:0032088=PMID:10383454, GO:0009615=PMID:12150927, GO:0005524=PMID:10383454, GO:0043242=PMID:12150927, GO:0010933=PMID:12150927, GO:0010936=PMID:12150927, GO:0004674=PMID:10383454, GO:0032695=PMID:12150927, GO:0032494=PMID:12150927, GO:0006468=PMID:10383454, GO:0043330=PMID:12150927} Q9Y616 Interleukin-1 receptor-associated kinase 3 protein 20090312 {GO:0005515=IPI, GO:0034122=ISS, GO:0032715=ISS, GO:0019221=ISS, GO:0005634=IDA, GO:0042803=IPI, GO:0005737=IDA, GO:0051092=IMP, GO:0046777=IEA, GO:0001960=IC, GO:0043244=ISS, GO:0002755=TAS, GO:0043407=IMP, GO:0032496=ISS, GO:0070555=IMP, GO:0070498=IMP, GO:0045824=ISS, GO:0000287=IDA, GO:0046982=IPI, GO:0042177=IMP, GO:0032720=IMP, GO:0032088=IMP, GO:0009615=IC, GO:0005524=IDA, GO:0043242=IMP, GO:0010933=ISS, GO:0010936=ISS, GO:0004674=IDA, GO:0032695=ISS, GO:0032494=ISS, GO:0006468=IDA, GO:0043330=ISS} MyD88-dependent toll-like receptor signaling pathway, cytokine-mediated signaling pathway, interleukin-1-mediated signaling pathway, negative regulation of MAP kinase activity, negative regulation of NF-kappaB transcription factor activity, negative regulation of cytokine-mediated signaling pathway, negative regulation of innate immune response, negative regulation of interleukin-12 production, negative regulation of interleukin-6 production, negative regulation of macrophage cytokine production, negative regulation of protein catabolic process, negative regulation of protein complex disassembly, negative regulation of toll-like receptor signaling pathway, negative regulation of tumor necrosis factor production, positive regulation of NF-kappaB transcription factor activity, positive regulation of macrophage tolerance induction, protein autophosphorylation, protein phosphorylation, regulation of protein complex disassembly, response to exogenous dsRNA, response to interleukin-1, response to lipopolysaccharide, response to peptidoglycan, response to virus cytoplasm, nucleus ATP binding, magnesium ion binding, protein binding, protein heterodimerization activity, protein homodimerization activity, protein serine/threonine kinase activity Human IRAK4 IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0005149=GO_REF:0000019, GO:0038124=Reactome:REACT_8006, GO:0034142=Reactome:REACT_6894, GO:0000287=GO_REF:0000002, GO:0038123=Reactome:REACT_8005, GO:0005886=Reactome:REACT_121298, GO:0034134=Reactome:REACT_7980, GO:0019221=GO_REF:0000019, GO:0007254=GO_REF:0000019, GO:0001816=GO_REF:0000019, GO:0002224=Reactome:REACT_9020, GO:0048661=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_27293, GO:0004672=Reactome:REACT_27228, GO:0004674=Reactome:REACT_24948, GO:0045087=Reactome:REACT_6802, GO:0045944=GO_REF:0000019, GO:0002755=Reactome:REACT_27215, GO:0034166=Reactome:REACT_9027, GO:0034146=Reactome:REACT_9061, GO:0034162=Reactome:REACT_9047, GO:0010008=Reactome:REACT_25312} Q9NWZ3 Interleukin-1 receptor-associated kinase 4 protein 20130415 {GO:0005515=IPI, GO:0005149=IEA, GO:0038124=TAS, GO:0034142=TAS, GO:0000287=IEA, GO:0038123=TAS, GO:0005886=TAS, GO:0034134=TAS, GO:0019221=IEA, GO:0007254=IEA, GO:0001816=IEA, GO:0002224=TAS, GO:0048661=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0004672=EXP, GO:0004674=TAS, GO:0045087=TAS, GO:0045944=IEA, GO:0002755=TAS, GO:0034166=TAS, GO:0034146=TAS, GO:0034162=TAS, GO:0010008=TAS} JNK cascade, MyD88-dependent toll-like receptor signaling pathway, cytokine production, cytokine-mediated signaling pathway, innate immune response, positive regulation of smooth muscle cell proliferation, positive regulation of transcription from RNA polymerase II promoter, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway cytosol, endosome membrane, plasma membrane ATP binding, interleukin-1 receptor binding, magnesium ion binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB:P58753 IREB2 UniProtKB UniProtKB {GO:0005515=PMID:19762596, GO:0051539=GO_REF:0000019, GO:0003723=PMID:9924025, GO:0007568=GO_REF:0000019, GO:0010040=GO_REF:0000019, GO:0030316=GO_REF:0000019, GO:0071456=GO_REF:0000019, GO:0034101=GO_REF:0000019, GO:0006782=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0006417=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0006879=GO_REF:0000019, GO:0005737=PMID:7983023, GO:0050892=GO_REF:0000019, GO:0008152=GO_REF:0000002, GO:0006826=PMID:9924025, GO:0030350=PMID:9924025, GO:0032526=GO_REF:0000019} P48200 Iron-responsive element-binding protein 2 protein 20111117 {GO:0005515=IPI, GO:0051539=IEA, GO:0003723=TAS, GO:0007568=IEA, GO:0010040=IEA, GO:0030316=IEA, GO:0071456=IEA, GO:0034101=IEA, GO:0006782=IEA, GO:0009791=IEA, GO:0046872=IEA, GO:0006417=IEA, GO:0005829=IEA, GO:0005739=IEA, GO:0006879=IEA, GO:0005737=NAS, GO:0050892=IEA, GO:0008152=IEA, GO:0006826=TAS, GO:0030350=TAS, GO:0032526=IEA} aging, cellular iron ion homeostasis, cellular response to hypoxia, erythrocyte homeostasis, intestinal absorption, iron ion transport, metabolic process, osteoclast differentiation, post-embryonic development, protoporphyrinogen IX biosynthetic process, regulation of translation, response to iron(II) ion, response to retinoic acid cytoplasm, cytosol, mitochondrion 4 iron, 4 sulfur cluster binding, RNA binding, iron-responsive element binding, metal ion binding, protein binding Human IRF1 BHF-UCL UniProtKB {GO:0005515=PMID:15509808, GO:0000790=PMID:18035482, GO:0003700=GO_REF:0000019, GO:0008285=PMID:11846974, GO:0035458=PMID:18035482, GO:0006366=PMID:2475256, GO:0019221=Reactome:REACT_25229, GO:0005634=PMID:11846971, GO:0005829=Reactome:REACT_25192, GO:0005737=GO_REF:0000024, GO:0051607=PMID:21389130, GO:0060337=Reactome:REACT_25162, GO:0045944=GO_REF:0000019, GO:0051726=PMID:11846974, GO:0032481=GO_REF:0000024, GO:0007050=PMID:22200613, GO:0060333=Reactome:REACT_25078, GO:0000975=GO_REF:0000002, GO:0032728=PMID:21389130, GO:2000564=GO_REF:0000024, GO:0006917=PMID:19851330, GO:0000978=PMID:18035482, GO:0003677=PMID:11846971, GO:0043565=GO_REF:0000019, GO:0002819=PMID:11846971, GO:0045084=GO_REF:0000019, GO:0043374=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0045088=PMID:11846971, GO:0034124=GO_REF:0000024, GO:0005654=Reactome:REACT_25334, GO:0071260=PMID:19593445, GO:0045893=PMID:15509808, GO:0045590=GO_REF:0000024, GO:0045892=PMID:18084608} P10914 Interferon regulatory factor 1 protein 20121126 {GO:0005515=IPI, GO:0000790=IDA, GO:0003700=IEA, GO:0008285=TAS, GO:0035458=IDA, GO:0006366=TAS, GO:0019221=TAS, GO:0005634=TAS, GO:0005829=TAS, GO:0005737=ISS, GO:0051607=IDA, GO:0060337=TAS, GO:0045944=IEA, GO:0051726=TAS, GO:0032481=ISS, GO:0007050=IDA, GO:0060333=TAS, GO:0000975=IEA, GO:0032728=IMP, GO:2000564=ISS, GO:0006917=IDA, GO:0000978=IDA, GO:0003677=TAS, GO:0043565=IEA, GO:0002819=TAS, GO:0045084=IEA, GO:0043374=IEA, GO:0007596=TAS, GO:0045088=TAS, GO:0034124=ISS, GO:0005654=TAS, GO:0071260=IEP, GO:0045893=IMP, GO:0045590=ISS, GO:0045892=IMP} CD8-positive, alpha-beta T cell differentiation, blood coagulation, cell cycle arrest, cellular response to interferon-beta, cellular response to mechanical stimulus, cytokine-mediated signaling pathway, defense response to virus, induction of apoptosis, interferon-gamma-mediated signaling pathway, negative regulation of cell proliferation, negative regulation of regulatory T cell differentiation, negative regulation of transcription, DNA-dependent, positive regulation of interferon-beta production, positive regulation of interleukin-12 biosynthetic process, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of type I interferon production, regulation of CD8-positive, alpha-beta T cell proliferation, regulation of MyD88-dependent toll-like receptor signaling pathway, regulation of adaptive immune response, regulation of cell cycle, regulation of innate immune response, transcription from RNA polymerase II promoter, type I interferon-mediated signaling pathway cytoplasm, cytosol, nuclear chromatin, nucleoplasm, nucleus DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, protein binding, regulatory region DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human IRF2 HPA UniProtKB {GO:0005515=PMID:21903422, GO:0000975=GO_REF:0000002, GO:0006355=PMID:9540062, GO:0003700=PMID:9540062, GO:0008283=PMID:8438157, GO:0019221=Reactome:REACT_25229, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000122=PMID:7507207, GO:0003677=PMID:9540062, GO:0006351=GO_REF:0000037, GO:0005829=Reactome:REACT_25192, GO:0060337=Reactome:REACT_25162, GO:0007596=Reactome:REACT_604, GO:0005654=Reactome:REACT_25232, GO:0005925=GO_REF:0000052, GO:0060333=Reactome:REACT_25078} P14316 Interferon regulatory factor 2 protein 20101115 {GO:0005515=IPI, GO:0000975=IEA, GO:0006355=IMP, GO:0003700=IMP, GO:0008283=TAS, GO:0019221=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0000122=TAS, GO:0003677=IDA, GO:0006351=IEA, GO:0005829=TAS, GO:0060337=TAS, GO:0007596=TAS, GO:0005654=TAS, GO:0005925=IDA, GO:0060333=TAS} blood coagulation, cell proliferation, cytokine-mediated signaling pathway, interferon-gamma-mediated signaling pathway, negative regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription, DNA-dependent, type I interferon-mediated signaling pathway cytosol, focal adhesion, nucleolus, nucleoplasm, nucleus DNA binding, protein binding, regulatory region DNA binding, sequence-specific DNA binding transcription factor activity Human IRF2BP1 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0016874=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8IU81 Interferon regulatory factor 2-binding protein 1 protein 20130413 {GO:0006355=IEA, GO:0016874=IEA, GO:0005634=IEA, GO:0046872=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus ligase activity, metal ion binding Human UniProtKB-SubCell:SL-0191 IRF2BP2 HPA UniProtKB {GO:0005737=GO_REF:0000039, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q7Z5L9 Interferon regulatory factor 2-binding protein 2 protein 20100326 {GO:0005737=IEA, GO:0006355=IEA, GO:0005634=IDA, GO:0046872=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus metal ion binding Human IRF2BPL UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005634=PMID:11095982, GO:0046872=GO_REF:0000037} Q9H1B7 Interferon regulatory factor 2-binding protein-like protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0005634=NAS, GO:0046872=IEA} biological_process nucleus metal ion binding, molecular_function Human IRF3 InterPro UniProtKB {GO:0005515=PMID:21988832, GO:0003700=GO_REF:0000002, GO:0034142=Reactome:REACT_6894, GO:0006366=PMID:8524823, GO:0019221=Reactome:REACT_25229, GO:0005634=PMID:17079289, GO:0042803=PMID:12062447, GO:0042802=PMID:22000020, GO:0005829=Reactome:REACT_147901, GO:0071888=PMID:16846591, GO:0002756=Reactome:REACT_6809, GO:0005737=PMID:17079289, GO:0051607=GO_REF:0000024, GO:0060337=Reactome:REACT_25162, GO:0032481=Reactome:REACT_147841, GO:0032480=Reactome:REACT_25271, GO:0034138=Reactome:REACT_6783, GO:0060333=Reactome:REACT_25078, GO:0003712=PMID:8524823, GO:0032728=GO_REF:0000024, GO:0000975=GO_REF:0000002, GO:0032727=GO_REF:0000024, GO:0006917=PMID:20049431, GO:0002224=Reactome:REACT_6966, GO:0003677=PMID:12062447, GO:0039530=PMID:16979567, GO:0006974=PMID:16979567, GO:0019048=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0005654=Reactome:REACT_118567, GO:0035666=Reactome:REACT_25281} Q7Z5G6 Interferon regulatory factor 3 protein 20130413 {GO:0005515=IPI, GO:0003700=IEA, GO:0034142=TAS, GO:0006366=TAS, GO:0019221=TAS, GO:0005634=IDA, GO:0042803=IPI, GO:0042802=IPI, GO:0005829=TAS, GO:0071888=TAS, GO:0002756=TAS, GO:0005737=IDA, GO:0051607=ISS, GO:0060337=TAS, GO:0032481=TAS, GO:0032480=TAS, GO:0034138=TAS, GO:0060333=TAS, GO:0003712=TAS, GO:0032728=ISS, GO:0000975=IEA, GO:0032727=ISS, GO:0006917=TAS, GO:0002224=TAS, GO:0003677=NAS, GO:0039530=TAS, GO:0006974=TAS, GO:0019048=IEA, GO:0045087=TAS, GO:0005654=TAS, GO:0035666=TAS} MDA-5 signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, cytokine-mediated signaling pathway, defense response to virus, induction of apoptosis, innate immune response, interferon-gamma-mediated signaling pathway, macrophage apoptotic process, negative regulation of type I interferon production, positive regulation of interferon-alpha production, positive regulation of interferon-beta production, positive regulation of type I interferon production, response to DNA damage stimulus, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor signaling pathway, transcription from RNA polymerase II promoter, type I interferon-mediated signaling pathway, virus-host interaction cytoplasm, cytosol, nucleoplasm, nucleus DNA binding, identical protein binding, protein binding, protein homodimerization activity, regulatory region DNA binding, sequence-specific DNA binding transcription factor activity, transcription cofactor activity Human InterPro:IPR019471|InterPro:IPR019817 IRF4 HPA UniProtKB {GO:0005515=PMID:21903422, GO:0003700=GO_REF:0000024, GO:0034122=GO_REF:0000019, GO:0045404=PMID:12374808, GO:0019221=Reactome:REACT_25229, GO:0005634=GO_REF:0000052, GO:0072540=GO_REF:0000024, GO:0005829=Reactome:REACT_25192, GO:0005737=GO_REF:0000052, GO:0060337=Reactome:REACT_25162, GO:0045944=GO_REF:0000019, GO:0000788=GO_REF:0000019, GO:0043011=GO_REF:0000019, GO:0045368=PMID:12374808, GO:0060333=Reactome:REACT_25078, GO:0000975=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0042832=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000024, GO:0045086=PMID:12374808, GO:0042110=PMID:12374808, GO:0043966=GO_REF:0000019, GO:0043967=GO_REF:0000019, GO:0043388=GO_REF:0000019, GO:0045893=PMID:12374808, GO:0045622=PMID:12374808, GO:0045082=PMID:12374808, GO:0008134=PMID:12374808} Q15306 Interferon regulatory factor 4 protein 20101115 {GO:0005515=IPI, GO:0003700=ISS, GO:0034122=IEA, GO:0045404=IDA, GO:0019221=TAS, GO:0005634=IDA, GO:0072540=ISS, GO:0005829=TAS, GO:0005737=IDA, GO:0060337=TAS, GO:0045944=IEA, GO:0000788=IEA, GO:0043011=IEA, GO:0045368=IDA, GO:0060333=TAS, GO:0000975=IEA, GO:0005730=IDA, GO:0042832=ISS, GO:0006351=IEA, GO:0043565=ISS, GO:0045086=IDA, GO:0042110=NAS, GO:0043966=IEA, GO:0043967=IEA, GO:0043388=IEA, GO:0045893=IDA, GO:0045622=NAS, GO:0045082=IDA, GO:0008134=NAS} T cell activation, T-helper 17 cell lineage commitment, cytokine-mediated signaling pathway, defense response to protozoan, histone H3 acetylation, histone H4 acetylation, interferon-gamma-mediated signaling pathway, myeloid dendritic cell differentiation, negative regulation of toll-like receptor signaling pathway, positive regulation of DNA binding, positive regulation of interleukin-10 biosynthetic process, positive regulation of interleukin-13 biosynthetic process, positive regulation of interleukin-2 biosynthetic process, positive regulation of interleukin-4 biosynthetic process, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of T-helper cell differentiation, transcription, DNA-dependent, type I interferon-mediated signaling pathway cytoplasm, cytosol, nuclear nucleosome, nucleolus, nucleus protein binding, regulatory region DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human IRF5 InterPro UniProtKB {GO:0005515=PMID:21988832, GO:0032728=PMID:22412986, GO:0000975=GO_REF:0000002, GO:0043065=PMID:22412986, GO:0003700=GO_REF:0000002, GO:0032727=PMID:22412986, GO:0019221=Reactome:REACT_25229, GO:0032735=PMID:22412986, GO:0005634=PMID:22412986, GO:0006351=GO_REF:0000037, GO:0005829=Reactome:REACT_25192, GO:0051607=GO_REF:0000019, GO:0005737=PMID:22412986, GO:0060337=Reactome:REACT_25162, GO:0032494=PMID:22412986, GO:0032495=PMID:22412986, GO:0060333=Reactome:REACT_25078} Q1A7B4 Interferon regulatory factor 5 protein 20130413 {GO:0005515=IPI, GO:0032728=IC, GO:0000975=IEA, GO:0043065=IMP, GO:0003700=IEA, GO:0032727=IC, GO:0019221=TAS, GO:0032735=IC, GO:0005634=IDA, GO:0006351=IEA, GO:0005829=TAS, GO:0051607=IEA, GO:0005737=IDA, GO:0060337=TAS, GO:0032494=IDA, GO:0032495=IDA, GO:0060333=TAS} cytokine-mediated signaling pathway, defense response to virus, interferon-gamma-mediated signaling pathway, positive regulation of apoptotic process, positive regulation of interferon-alpha production, positive regulation of interferon-beta production, positive regulation of interleukin-12 production, response to muramyl dipeptide, response to peptidoglycan, transcription, DNA-dependent, type I interferon-mediated signaling pathway cytoplasm, cytosol, nucleus protein binding, regulatory region DNA binding, sequence-specific DNA binding transcription factor activity Human InterPro:IPR019817 IRF6 IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0000975=GO_REF:0000002, GO:0003700=GO_REF:0000024, GO:0008285=PMID:18212048, GO:0019221=Reactome:REACT_25229, GO:0005634=GO_REF:0000039, GO:0043616=GO_REF:0000019, GO:0003677=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0005829=Reactome:REACT_25192, GO:0005737=PMID:18212048, GO:0060337=Reactome:REACT_25162, GO:0060644=GO_REF:0000024, GO:0030216=GO_REF:0000019, GO:0007050=PMID:18212048, GO:0043588=GO_REF:0000019, GO:0048468=GO_REF:0000019, GO:0045893=GO_REF:0000024, GO:0060333=Reactome:REACT_25078} O14896 Interferon regulatory factor 6 protein 20130415 {GO:0005515=IPI, GO:0000975=IEA, GO:0003700=ISS, GO:0008285=IDA, GO:0019221=TAS, GO:0005634=IEA, GO:0043616=IEA, GO:0003677=ISS, GO:0006351=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0060337=TAS, GO:0060644=ISS, GO:0030216=IEA, GO:0007050=IDA, GO:0043588=IEA, GO:0048468=IEA, GO:0045893=ISS, GO:0060333=TAS} cell cycle arrest, cell development, cytokine-mediated signaling pathway, interferon-gamma-mediated signaling pathway, keratinocyte differentiation, keratinocyte proliferation, mammary gland epithelial cell differentiation, negative regulation of cell proliferation, positive regulation of transcription, DNA-dependent, skin development, transcription, DNA-dependent, type I interferon-mediated signaling pathway cytoplasm, cytosol, nucleus DNA binding, protein binding, regulatory region DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:Q02556 IRF7 BHF-UCL UniProtKB {GO:0005515=PMID:20392859, GO:0032479=PMID:21490621, GO:0034142=Reactome:REACT_6894, GO:0016064=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0006366=PMID:9315633, GO:0019221=Reactome:REACT_25229, GO:0000982=PMID:17404045, GO:0045351=GO_REF:0000019, GO:0005634=PMID:9786932, GO:0005829=Reactome:REACT_25368, GO:0002756=Reactome:REACT_6809, GO:0005737=PMID:9786932, GO:0060337=Reactome:REACT_25162, GO:0045655=PMID:21490621, GO:0045944=PMID:16127453, GO:0034138=Reactome:REACT_6783, GO:0032607=GO_REF:0000024, GO:0060333=Reactome:REACT_25078, GO:0032608=GO_REF:0000024, GO:0000975=GO_REF:0000002, GO:0032728=PMID:16979567, GO:0032727=PMID:16127453, GO:0000122=PMID:9315633, GO:2000110=PMID:21490621, GO:0009615=PMID:21490621, GO:0002224=Reactome:REACT_9020, GO:0000979=PMID:17404045, GO:0003677=PMID:12374802, GO:0039530=PMID:16979567, GO:0006974=PMID:16979567, GO:0002819=PMID:17404045, GO:0045087=Reactome:REACT_6802, GO:0050776=PMID:21490621, GO:0034124=GO_REF:0000024, GO:0019043=PMID:21490621, GO:0060340=GO_REF:0000019, GO:0035666=Reactome:REACT_25281, GO:0005654=Reactome:REACT_25352, GO:0034127=GO_REF:0000024, GO:0045893=PMID:12374802, GO:0034162=Reactome:REACT_9047, GO:0010008=Reactome:REACT_25312} Q92985 Interferon regulatory factor 7 protein 20110201 {GO:0005515=IPI, GO:0032479=TAS, GO:0034142=TAS, GO:0016064=IEA, GO:0003700=IEA, GO:0006366=TAS, GO:0019221=TAS, GO:0000982=IDA, GO:0045351=IEA, GO:0005634=TAS, GO:0005829=TAS, GO:0002756=TAS, GO:0005737=TAS, GO:0060337=TAS, GO:0045655=TAS, GO:0045944=IDA, GO:0034138=TAS, GO:0032607=ISS, GO:0060333=TAS, GO:0032608=ISS, GO:0000975=IEA, GO:0032728=TAS, GO:0032727=IDA, GO:0000122=TAS, GO:2000110=TAS, GO:0009615=TAS, GO:0002224=TAS, GO:0000979=IDA, GO:0003677=IMP, GO:0039530=TAS, GO:0006974=TAS, GO:0002819=IDA, GO:0045087=TAS, GO:0050776=TAS, GO:0034124=ISS, GO:0019043=TAS, GO:0060340=IEA, GO:0035666=TAS, GO:0005654=TAS, GO:0034127=ISS, GO:0045893=IMP, GO:0034162=TAS, GO:0010008=TAS} MDA-5 signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, cytokine-mediated signaling pathway, establishment of viral latency, immunoglobulin mediated immune response, innate immune response, interferon-alpha production, interferon-beta production, interferon-gamma-mediated signaling pathway, negative regulation of macrophage apoptotic process, negative regulation of transcription from RNA polymerase II promoter, positive regulation of interferon-alpha production, positive regulation of interferon-beta production, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of type I interferon-mediated signaling pathway, regulation of MyD88-dependent toll-like receptor signaling pathway, regulation of MyD88-independent toll-like receptor signaling pathway, regulation of adaptive immune response, regulation of immune response, regulation of monocyte differentiation, regulation of type I interferon production, response to DNA damage stimulus, response to virus, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor signaling pathway, transcription from RNA polymerase II promoter, type I interferon biosynthetic process, type I interferon-mediated signaling pathway cytoplasm, cytosol, endosome membrane, nucleoplasm, nucleus DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding, protein binding, regulatory region DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:P21580 IRF8 IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0006909=GO_REF:0000019, GO:0032729=GO_REF:0000019, GO:0000975=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0003705=PMID:1460054, GO:0019221=Reactome:REACT_25229, GO:0042832=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0032735=GO_REF:0000019, GO:0000122=PMID:1460054, GO:0003677=GO_REF:0000019, GO:0005829=Reactome:REACT_25192, GO:0006955=PMID:8861914, GO:0060337=Reactome:REACT_25162, GO:0071222=GO_REF:0000019, GO:0030099=GO_REF:0000019, GO:0044130=GO_REF:0000019, GO:0045893=GO_REF:0000019, GO:0042742=GO_REF:0000019, GO:0060333=Reactome:REACT_25078} Q02556 Interferon regulatory factor 8 protein 20130415 {GO:0005515=IPI, GO:0006909=IEA, GO:0032729=IEA, GO:0000975=IEA, GO:0003700=IEA, GO:0003705=TAS, GO:0019221=TAS, GO:0042832=IEA, GO:0005634=IEA, GO:0032735=IEA, GO:0000122=TAS, GO:0003677=IEA, GO:0005829=TAS, GO:0006955=TAS, GO:0060337=TAS, GO:0071222=IEA, GO:0030099=IEA, GO:0044130=IEA, GO:0045893=IEA, GO:0042742=IEA, GO:0060333=TAS} cellular response to lipopolysaccharide, cytokine-mediated signaling pathway, defense response to bacterium, defense response to protozoan, immune response, interferon-gamma-mediated signaling pathway, myeloid cell differentiation, negative regulation of growth of symbiont in host, negative regulation of transcription from RNA polymerase II promoter, phagocytosis, positive regulation of interferon-gamma production, positive regulation of interleukin-12 production, positive regulation of transcription, DNA-dependent, type I interferon-mediated signaling pathway cytosol, nucleus DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, protein binding, regulatory region DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:O14896 IRF9 HPA UniProtKB {GO:0005515=PMID:21903422, GO:0000975=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0006366=PMID:1630447, GO:0019221=Reactome:REACT_25229, GO:0045351=GO_REF:0000019, GO:0005634=PMID:1630447, GO:0005829=Reactome:REACT_25284, GO:0005737=GO_REF:0000052, GO:0051607=GO_REF:0000037, GO:0060337=Reactome:REACT_25162, GO:0005654=Reactome:REACT_25169, GO:0007166=PMID:1630447, GO:0060333=Reactome:REACT_25078} Q00978 Interferon regulatory factor 9 protein 20080205 {GO:0005515=IPI, GO:0000975=IEA, GO:0003700=IEA, GO:0006366=TAS, GO:0019221=TAS, GO:0045351=IEA, GO:0005634=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0051607=IEA, GO:0060337=TAS, GO:0005654=TAS, GO:0007166=TAS, GO:0060333=TAS} cell surface receptor signaling pathway, cytokine-mediated signaling pathway, defense response to virus, interferon-gamma-mediated signaling pathway, transcription from RNA polymerase II promoter, type I interferon biosynthetic process, type I interferon-mediated signaling pathway cytoplasm, cytosol, nucleoplasm, nucleus protein binding, regulatory region DNA binding, sequence-specific DNA binding transcription factor activity Human IRGC ENSEMBL UniProtKB {GO:0050829=GO_REF:0000019, GO:0016817=GO_REF:0000002, GO:0035458=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0020005=GO_REF:0000019, GO:0005789=GO_REF:0000019, GO:0003924=GO_REF:0000019, GO:0042832=GO_REF:0000019, GO:0010506=GO_REF:0000019, GO:0019003=GO_REF:0000019, GO:0005525=GO_REF:0000019, GO:0042802=GO_REF:0000019} Q6NXR0 Interferon-inducible GTPase 5 protein 20130413 {GO:0050829=IEA, GO:0016817=IEA, GO:0035458=IEA, GO:0016020=IEA, GO:0020005=IEA, GO:0005789=IEA, GO:0003924=IEA, GO:0042832=IEA, GO:0010506=IEA, GO:0019003=IEA, GO:0005525=IEA, GO:0042802=IEA} cellular response to interferon-beta, defense response to Gram-negative bacterium, defense response to protozoan, regulation of autophagy endoplasmic reticulum membrane, membrane, symbiont-containing vacuole membrane GDP binding, GTP binding, GTPase activity, hydrolase activity, acting on acid anhydrides, identical protein binding Human Ensembl:ENSMUSP00000032473 IRGQ null null {} null null null null {} null null null IRS1 BHF-UCL UniProtKB {GO:0008286=PMID:16516141, GO:0005515=PMID:7559478, GO:0010468=GO_REF:0000019, GO:0008284=PMID:17925406, GO:0034504=GO_REF:0000019, GO:0005886=Reactome:REACT_150315, GO:0005159=PMID:7541045, GO:0005158=PMID:7537849, GO:0043434=GO_REF:0000024, GO:0030879=GO_REF:0000019, GO:0005634=GO_REF:0000024, GO:0060397=Reactome:REACT_111133, GO:0010907=PMID:16814735, GO:0043231=GO_REF:0000024, GO:0005829=Reactome:REACT_12384, GO:0005737=GO_REF:0000024, GO:0005543=GO_REF:0000002, GO:0043552=GO_REF:0000024, GO:0007173=Reactome:REACT_9417, GO:0046326=PMID:16814735, GO:0005899=GO_REF:0000024, GO:0005080=GO_REF:0000024, GO:0005068=GO_REF:0000024, GO:0004871=GO_REF:0000037, GO:0046676=PMID:15572028, GO:0042169=GO_REF:0000024, GO:0032868=PMID:16516141, GO:0032869=PMID:16814735, GO:0048011=Reactome:REACT_11061, GO:0030335=GO_REF:0000019, GO:0045725=PMID:17925406, GO:0046627=GO_REF:0000024, GO:0048015=Reactome:REACT_12464, GO:0046628=GO_REF:0000024, GO:0002053=GO_REF:0000019, GO:0042593=PMID:16814735, GO:0014065=PMID:7782332, GO:0016042=GO_REF:0000019, GO:2001275=PMID:7493946, GO:0007165=PMID:1311924, GO:0008543=Reactome:REACT_9470, GO:0005901=PMID:15182363, GO:0045087=Reactome:REACT_6802, GO:0032000=PMID:16814735, GO:0043491=GO_REF:0000019, GO:0048009=PMID:7541045, GO:0043548=PMID:7782332} P35568 Insulin receptor substrate 1 protein 20100121 {GO:0008286=IDA, GO:0005515=IPI, GO:0010468=IEA, GO:0008284=NAS, GO:0034504=IEA, GO:0005886=TAS, GO:0005159=IPI, GO:0005158=IPI, GO:0043434=ISS, GO:0030879=IEA, GO:0005634=ISS, GO:0060397=TAS, GO:0010907=IMP, GO:0043231=ISS, GO:0005829=TAS, GO:0005737=ISS, GO:0005543=IEA, GO:0043552=ISS, GO:0007173=TAS, GO:0046326=IMP, GO:0005899=ISS, GO:0005080=ISS, GO:0005068=ISS, GO:0004871=IEA, GO:0046676=IDA, GO:0042169=ISS, GO:0032868=IDA, GO:0032869=IMP, GO:0048011=TAS, GO:0030335=IEA, GO:0045725=NAS, GO:0046627=ISS, GO:0048015=TAS, GO:0046628=ISS, GO:0002053=IEA, GO:0042593=TAS, GO:0014065=IDA, GO:0016042=IEA, GO:2001275=IDA, GO:0007165=TAS, GO:0008543=TAS, GO:0005901=IDA, GO:0045087=TAS, GO:0032000=IMP, GO:0043491=IEA, GO:0048009=IPI, GO:0043548=IPI} JAK-STAT cascade involved in growth hormone signaling pathway, cellular response to insulin stimulus, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, glucose homeostasis, innate immune response, insulin receptor signaling pathway, insulin-like growth factor receptor signaling pathway, lipid catabolic process, mammary gland development, negative regulation of insulin receptor signaling pathway, negative regulation of insulin secretion, neurotrophin TRK receptor signaling pathway, phosphatidylinositol 3-kinase cascade, phosphatidylinositol-mediated signaling, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of fatty acid beta-oxidation, positive regulation of glucose import, positive regulation of glucose import in response to insulin stimulus, positive regulation of glucose metabolic process, positive regulation of glycogen biosynthetic process, positive regulation of insulin receptor signaling pathway, positive regulation of mesenchymal cell proliferation, positive regulation of phosphatidylinositol 3-kinase activity, protein kinase B signaling cascade, protein localization to nucleus, regulation of gene expression, response to insulin stimulus, response to peptide hormone stimulus, signal transduction caveola, cytoplasm, cytosol, insulin receptor complex, intracellular membrane-bounded organelle, nucleus, plasma membrane SH2 domain binding, insulin receptor binding, insulin-like growth factor receptor binding, phosphatidylinositol 3-kinase binding, phospholipid binding, protein binding, protein kinase C binding, signal transducer activity, transmembrane receptor protein tyrosine kinase adaptor activity Human IRS2 BHF-UCL UniProtKB {GO:0008286=GO_REF:0000024, GO:0005515=PMID:21241768, GO:0008284=PMID:17925406, GO:0005886=Reactome:REACT_150340, GO:0030890=GO_REF:0000024, GO:0008283=GO_REF:0000019, GO:0005158=GO_REF:0000002, GO:0030879=GO_REF:0000019, GO:0060397=Reactome:REACT_111133, GO:0005829=Reactome:REACT_150340, GO:0010907=PMID:16814735, GO:0005543=GO_REF:0000002, GO:0007173=Reactome:REACT_9417, GO:0002903=GO_REF:0000024, GO:0046326=PMID:16814735, GO:0006006=PMID:9495343, GO:0032024=GO_REF:0000024, GO:0004871=GO_REF:0000037, GO:0033673=GO_REF:0000024, GO:0048011=Reactome:REACT_11061, GO:0032869=PMID:16814735, GO:0030335=GO_REF:0000019, GO:0045725=PMID:17925406, GO:0019901=GO_REF:0000019, GO:0048015=Reactome:REACT_12464, GO:0055088=PMID:16814735, GO:0010748=PMID:16814735, GO:0002053=GO_REF:0000019, GO:0009749=GO_REF:0000024, GO:0019216=PMID:16814735, GO:0007165=PMID:7675087, GO:0007420=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0032000=PMID:16814735, GO:0043548=GO_REF:0000019} Q9Y4H2 Insulin receptor substrate 2 protein 20100120 {GO:0008286=ISS, GO:0005515=IPI, GO:0008284=NAS, GO:0005886=TAS, GO:0030890=ISS, GO:0008283=IEA, GO:0005158=IEA, GO:0030879=IEA, GO:0060397=TAS, GO:0005829=TAS, GO:0010907=IMP, GO:0005543=IEA, GO:0007173=TAS, GO:0002903=ISS, GO:0046326=IMP, GO:0006006=TAS, GO:0032024=ISS, GO:0004871=IEA, GO:0033673=ISS, GO:0048011=TAS, GO:0032869=IMP, GO:0030335=IEA, GO:0045725=NAS, GO:0019901=IEA, GO:0048015=TAS, GO:0055088=TAS, GO:0010748=IMP, GO:0002053=IEA, GO:0009749=ISS, GO:0019216=TAS, GO:0007165=TAS, GO:0007420=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:0032000=IMP, GO:0043548=IEA} JAK-STAT cascade involved in growth hormone signaling pathway, brain development, cell proliferation, cellular response to insulin stimulus, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, glucose metabolic process, innate immune response, insulin receptor signaling pathway, lipid homeostasis, mammary gland development, negative regulation of B cell apoptotic process, negative regulation of kinase activity, negative regulation of plasma membrane long-chain fatty acid transport, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of B cell proliferation, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of fatty acid beta-oxidation, positive regulation of glucose import, positive regulation of glucose metabolic process, positive regulation of glycogen biosynthetic process, positive regulation of insulin secretion, positive regulation of mesenchymal cell proliferation, regulation of lipid metabolic process, response to glucose stimulus, signal transduction cytosol, plasma membrane insulin receptor binding, phosphatidylinositol 3-kinase binding, phospholipid binding, protein binding, protein kinase binding, signal transducer activity Human UniProtKB:P81122 IRS4 Reactome UniProtKB {GO:0007165=PMID:9261155, GO:0005543=GO_REF:0000002, GO:0005886=Reactome:REACT_150315, GO:0005070=PMID:9261155, GO:0005158=GO_REF:0000002, GO:0004871=GO_REF:0000037} O14654 Insulin receptor substrate 4 protein 20120724 {GO:0007165=TAS, GO:0005543=IEA, GO:0005886=TAS, GO:0005070=TAS, GO:0005158=IEA, GO:0004871=IEA} signal transduction plasma membrane SH3/SH2 adaptor activity, insulin receptor binding, phospholipid binding, signal transducer activity Human IRX1 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0072272=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0072086=GO_REF:0000019} P78414 Iroquois-class homeodomain protein IRX-1 protein 20130413 {GO:0043565=IEA, GO:0003700=IEA, GO:0072272=IEA, GO:0005634=IEA, GO:0072086=IEA} proximal/distal pattern formation involved in metanephric nephron development, specification of loop of Henle identity nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0191 IRX2 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0072272=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0072086=GO_REF:0000019} Q9BZI1 Iroquois-class homeodomain protein IRX-2 protein 20130413 {GO:0043565=IEA, GO:0003700=IEA, GO:0072272=IEA, GO:0005634=IEA, GO:0072086=IEA} proximal/distal pattern formation involved in metanephric nephron development, specification of loop of Henle identity nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0191 IRX4 UniProtKB UniProtKB {GO:0007507=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000002, GO:0048561=GO_REF:0000019} P78413 Iroquois-class homeodomain protein IRX-4 protein 20130413 {GO:0007507=IEA, GO:0043565=IEA, GO:0006355=IEA, GO:0003700=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0048561=IEA} establishment of organ orientation, heart development, regulation of transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0191 IRX5 UniProtKB UniProtKB {GO:0008406=PMID:22581230, GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0002027=GO_REF:0000019, GO:0060040=GO_REF:0000019, GO:0042551=GO_REF:0000019, GO:0005499=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0048701=PMID:22581230, GO:0007601=GO_REF:0000037, GO:0050896=GO_REF:0000037, GO:0006351=GO_REF:0000037} P78411 Iroquois-class homeodomain protein IRX-5 protein 20120814 {GO:0008406=IMP, GO:0043565=IEA, GO:0003700=IEA, GO:0002027=IEA, GO:0060040=IEA, GO:0042551=IEA, GO:0005499=IEA, GO:0005634=IEA, GO:0048701=IMP, GO:0007601=IEA, GO:0050896=IEA, GO:0006351=IEA} embryonic cranial skeleton morphogenesis, gonad development, neuron maturation, regulation of heart rate, response to stimulus, retinal bipolar neuron differentiation, transcription, DNA-dependent, visual perception nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, vitamin D binding Human ISCA1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0051536=GO_REF:0000037, GO:0016226=GO_REF:0000002, GO:0005198=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q9BUE6 Iron-sulfur cluster assembly 1 homolog, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0051536=IEA, GO:0016226=IEA, GO:0005198=IEA, GO:0046872=IEA} iron-sulfur cluster assembly mitochondrion iron-sulfur cluster binding, metal ion binding, structural molecule activity Human UniProtKB-SubCell:SL-0173 ISCU LIFEdb UniProtKB {GO:0005515=PMID:16527810, GO:0005739=PMID:11060020, GO:0009399=PMID:8875867, GO:0032947=PMID:16527810, GO:0005737=GO_REF:0000054, GO:0051536=GO_REF:0000002, GO:0016226=PMID:11060020, GO:0005506=PMID:11060020, GO:0005759=Reactome:REACT_150385, GO:0005634=PMID:16527810, GO:0044281=Reactome:REACT_111217, GO:0005829=PMID:16527810} Q9H1K1 Iron-sulfur cluster assembly enzyme ISCU, mitochondrial protein 20100607 {GO:0005515=IPI, GO:0005739=IDA, GO:0009399=TAS, GO:0032947=IDA, GO:0005737=IDA, GO:0051536=IEA, GO:0016226=TAS, GO:0005506=TAS, GO:0005759=TAS, GO:0005634=TAS, GO:0044281=TAS, GO:0005829=IDA} iron-sulfur cluster assembly, nitrogen fixation, small molecule metabolic process cytoplasm, cytosol, mitochondrial matrix, mitochondrion, nucleus iron ion binding, iron-sulfur cluster binding, protein binding, protein complex scaffold Human ISG15 Reactome UniProtKB {GO:0032020=PMID:16122702, GO:0019221=Reactome:REACT_25229, GO:0007267=GO_REF:0000029, GO:0005615=GO_REF:0000029, GO:0005829=Reactome:REACT_116157, GO:0051607=GO_REF:0000037, GO:0005737=GO_REF:0000029, GO:0060337=Reactome:REACT_25162, GO:0019048=GO_REF:0000037, GO:0019941=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0031386=GO_REF:0000019, GO:0032480=Reactome:REACT_25271} P05161 Ubiquitin-like protein ISG15 protein 20130228 {GO:0032020=IDA, GO:0019221=TAS, GO:0007267=NAS, GO:0005615=NAS, GO:0005829=TAS, GO:0051607=IEA, GO:0005737=NAS, GO:0060337=TAS, GO:0019048=IEA, GO:0019941=IEA, GO:0045087=TAS, GO:0031386=IEA, GO:0032480=TAS} ISG15-protein conjugation, cell-cell signaling, cytokine-mediated signaling pathway, defense response to virus, innate immune response, modification-dependent protein catabolic process, negative regulation of type I interferon production, type I interferon-mediated signaling pathway, virus-host interaction cytoplasm, cytosol, extracellular space protein tag Human ISG20 Reactome UniProtKB {GO:0008283=PMID:9569007, GO:0008310=PMID:11401564, GO:0003723=GO_REF:0000037, GO:0006364=GO_REF:0000037, GO:0019221=Reactome:REACT_25229, GO:0009615=PMID:12594219, GO:0003676=GO_REF:0000002, GO:0008859=GO_REF:0000003, GO:0046872=GO_REF:0000037, GO:0006401=PMID:11401564, GO:0005622=GO_REF:0000002, GO:0004527=GO_REF:0000002, GO:0051607=GO_REF:0000037, GO:0060337=Reactome:REACT_25162, GO:0000175=PMID:11401564, GO:0016605=PMID:9235947, GO:0005654=Reactome:REACT_25192, GO:0000738=PMID:11401564} Q96AZ6 Interferon-stimulated gene 20 kDa protein protein 20130228 {GO:0008283=TAS, GO:0008310=IDA, GO:0003723=IEA, GO:0006364=IEA, GO:0019221=TAS, GO:0009615=IDA, GO:0003676=IEA, GO:0008859=IEA, GO:0046872=IEA, GO:0006401=IDA, GO:0005622=IEA, GO:0004527=IEA, GO:0051607=IEA, GO:0060337=TAS, GO:0000175=IDA, GO:0016605=IDA, GO:0005654=TAS, GO:0000738=IDA} DNA catabolic process, exonucleolytic, RNA catabolic process, cell proliferation, cytokine-mediated signaling pathway, defense response to virus, rRNA processing, response to virus, type I interferon-mediated signaling pathway PML body, intracellular, nucleoplasm 3'-5'-exoribonuclease activity, RNA binding, exonuclease activity, exoribonuclease II activity, metal ion binding, nucleic acid binding, single-stranded DNA specific 3'-5' exodeoxyribonuclease activity Human ISG20L2 HPA UniProtKB {GO:0005515=PMID:19060904, GO:0004527=GO_REF:0000037, GO:0042254=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0043231=GO_REF:0000052} Q9H9L3 Interferon-stimulated 20 kDa exonuclease-like 2 protein 20101115 {GO:0005515=IPI, GO:0004527=IEA, GO:0042254=IEA, GO:0005730=IEA, GO:0005634=IDA, GO:0003676=IEA, GO:0043231=IDA} ribosome biogenesis intracellular membrane-bounded organelle, nucleolus, nucleus exonuclease activity, nucleic acid binding, protein binding Human ISL1 BHF-UCL UniProtKB {GO:0032755=GO_REF:0000024, GO:0003700=GO_REF:0000002, GO:0055010=GO_REF:0000024, GO:0001755=GO_REF:0000019, GO:0003139=PMID:20520780, GO:0021559=GO_REF:0000024, GO:0060913=PMID:19571884, GO:0043524=GO_REF:0000024, GO:0060379=GO_REF:0000019, GO:0032024=PMID:19619559, GO:0032729=GO_REF:0000024, GO:0001102=PMID:19619559, GO:0016922=GO_REF:0000024, GO:1901258=GO_REF:0000024, GO:0001105=PMID:19619559, GO:0032760=GO_REF:0000024, GO:0032725=GO_REF:0000024, GO:0030331=GO_REF:0000024, GO:0000122=GO_REF:0000024, GO:0060037=GO_REF:0000024, GO:0071385=GO_REF:0000024, GO:0060384=GO_REF:0000024, GO:0043388=GO_REF:0000019, GO:0048880=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0048936=GO_REF:0000024, GO:0033147=GO_REF:0000024, GO:0001158=PMID:19619559, GO:0031290=GO_REF:0000019, GO:0032730=GO_REF:0000024, GO:0008284=GO_REF:0000019, GO:0031103=GO_REF:0000019, GO:0071657=GO_REF:0000024, GO:0032731=GO_REF:0000024, GO:0021983=GO_REF:0000019, GO:0032735=GO_REF:0000024, GO:0005634=PMID:7907017, GO:0003215=GO_REF:0000024, GO:0005737=PMID:7907017, GO:0045944=GO_REF:0000024, GO:0090090=GO_REF:0000019, GO:0003266=GO_REF:0000019, GO:0021524=GO_REF:0000019, GO:0021522=GO_REF:0000024, GO:0090074=GO_REF:0000024, GO:0021520=GO_REF:0000019, GO:0060413=GO_REF:0000024, GO:0042517=GO_REF:0000019, GO:0048762=GO_REF:0000024, GO:0048665=GO_REF:0000024, GO:0003203=GO_REF:0000024, GO:0043425=PMID:16321656, GO:0010575=GO_REF:0000024, GO:0045766=GO_REF:0000024, GO:0003151=GO_REF:0000024, GO:0043565=GO_REF:0000002, GO:0031016=GO_REF:0000024, GO:0045665=GO_REF:0000019, GO:0050728=GO_REF:0000024, GO:0003682=GO_REF:0000019, GO:0003148=GO_REF:0000024} P61371 Insulin gene enhancer protein ISL-1 protein 20120806 {GO:0032755=ISS, GO:0003700=IEA, GO:0055010=ISS, GO:0001755=IEA, GO:0003139=IMP, GO:0021559=ISS, GO:0060913=IDA, GO:0043524=ISS, GO:0060379=IEA, GO:0032024=IC, GO:0032729=ISS, GO:0001102=IPI, GO:0016922=ISS, GO:1901258=ISS, GO:0001105=IDA, GO:0032760=ISS, GO:0032725=ISS, GO:0030331=ISS, GO:0000122=ISS, GO:0060037=ISS, GO:0071385=ISS, GO:0060384=ISS, GO:0043388=IEA, GO:0048880=ISS, GO:0008270=IEA, GO:0048936=ISS, GO:0033147=ISS, GO:0001158=IDA, GO:0031290=IEA, GO:0032730=ISS, GO:0008284=IEA, GO:0031103=IEA, GO:0071657=ISS, GO:0032731=ISS, GO:0021983=IEA, GO:0032735=ISS, GO:0005634=NAS, GO:0003215=ISS, GO:0005737=NAS, GO:0045944=ISS, GO:0090090=IEA, GO:0003266=IEA, GO:0021524=IEA, GO:0021522=ISS, GO:0090074=ISS, GO:0021520=IEA, GO:0060413=ISS, GO:0042517=IEA, GO:0048762=ISS, GO:0048665=ISS, GO:0003203=ISS, GO:0043425=IPI, GO:0010575=ISS, GO:0045766=ISS, GO:0003151=ISS, GO:0043565=IEA, GO:0031016=ISS, GO:0045665=IEA, GO:0050728=ISS, GO:0003682=IEA, GO:0003148=ISS} atrial septum morphogenesis, axon regeneration, cardiac cell fate determination, cardiac muscle cell myoblast differentiation, cardiac right ventricle morphogenesis, cellular response to glucocorticoid stimulus, endocardial cushion morphogenesis, innervation, mesenchymal cell differentiation, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of inflammatory response, negative regulation of intracellular estrogen receptor signaling pathway, negative regulation of neuron apoptotic process, negative regulation of neuron differentiation, negative regulation of protein homodimerization activity, negative regulation of transcription from RNA polymerase II promoter, neural crest cell migration, neuron fate specification, outflow tract morphogenesis, outflow tract septum morphogenesis, pancreas development, peripheral nervous system neuron axonogenesis, pharyngeal system development, pituitary gland development, positive regulation of DNA binding, positive regulation of angiogenesis, positive regulation of cell proliferation, positive regulation of granulocyte colony-stimulating factor production, positive regulation of granulocyte macrophage colony-stimulating factor production, positive regulation of insulin secretion, positive regulation of interferon-gamma production, positive regulation of interleukin-1 alpha production, positive regulation of interleukin-1 beta production, positive regulation of interleukin-12 production, positive regulation of interleukin-6 production, positive regulation of macrophage colony-stimulating factor production, positive regulation of transcription from RNA polymerase II promoter, positive regulation of tumor necrosis factor production, positive regulation of tyrosine phosphorylation of Stat3 protein, positive regulation vascular endothelial growth factor production, regulation of secondary heart field cardioblast proliferation, retinal ganglion cell axon guidance, secondary heart field specification, sensory system development, spinal cord motor neuron cell fate specification, spinal cord motor neuron differentiation, trigeminal nerve development, ventricular cardiac muscle tissue morphogenesis, visceral motor neuron differentiation cytoplasm, nucleus RNA polymerase II activating transcription factor binding, RNA polymerase II transcription coactivator activity, bHLH transcription factor binding, chromatin binding, enhancer sequence-specific DNA binding, estrogen receptor binding, ligand-dependent nuclear receptor binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB:P61372 ISL2 BHF-UCL UniProtKB {GO:0043565=GO_REF:0000002, GO:0031290=GO_REF:0000019, GO:0005622=GO_REF:0000019, GO:0021524=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0045665=GO_REF:0000019, GO:0048666=PMID:9452425, GO:0021520=GO_REF:0000019, GO:0048935=PMID:20096094, GO:0005634=PMID:17091338, GO:0008270=GO_REF:0000002, GO:0003677=PMID:17091338} Q96A47 Insulin gene enhancer protein ISL-2 protein 20110921 {GO:0043565=IEA, GO:0031290=IEA, GO:0005622=IEA, GO:0021524=IEA, GO:0003700=IEA, GO:0045665=IEA, GO:0048666=TAS, GO:0021520=IEA, GO:0048935=TAS, GO:0005634=IC, GO:0008270=IEA, GO:0003677=ISS} negative regulation of neuron differentiation, neuron development, peripheral nervous system neuron development, retinal ganglion cell axon guidance, spinal cord motor neuron cell fate specification, visceral motor neuron differentiation intracellular, nucleus DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ISOC1 HGNC UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0003824=GO_REF:0000002, GO:0005777=PMID:14561759} Q96CN7 Isochorismatase domain-containing protein 1 protein 20061204 {GO:0003674=ND, GO:0008150=ND, GO:0003824=IEA, GO:0005777=ISS} biological_process peroxisome catalytic activity, molecular_function Human UniProtKB:Q6I7R3 ISOC2 BHF-UCL UniProtKB {GO:0031648=PMID:17658461, GO:0005515=PMID:17658461, GO:0005739=GO_REF:0000039, GO:0005737=PMID:17658461, GO:0005634=PMID:17658461, GO:0003824=GO_REF:0000002} Q96AB3 Isochorismatase domain-containing protein 2, mitochondrial protein 20071114 {GO:0031648=IMP, GO:0005515=IPI, GO:0005739=IEA, GO:0005737=IDA, GO:0005634=IDA, GO:0003824=IEA} protein destabilization cytoplasm, mitochondrion, nucleus catalytic activity, protein binding Human IST1 IntAct UniProtKB {GO:0019076=PMID:19129479, GO:0005515=PMID:16713569, GO:0090541=PMID:19129479, GO:0005793=PMID:10942595, GO:0090543=PMID:19129479, GO:0019904=PMID:20719964, GO:0016023=GO_REF:0000039, GO:0046746=PMID:19129479, GO:0051301=PMID:20719964, GO:0009838=PMID:19129479, GO:0005829=PMID:19129480} P53990 IST1 homolog protein 20130415 {GO:0019076=IDA, GO:0005515=IPI, GO:0090541=IPI, GO:0005793=IDA, GO:0090543=IDA, GO:0019904=IPI, GO:0016023=IEA, GO:0046746=IDA, GO:0051301=IMP, GO:0009838=IDA, GO:0005829=IDA} abscission, cell division, viral release from host cell, virus budding from nuclear membrane by viral capsid re-envelopment Flemming body, cytoplasmic membrane-bounded vesicle, cytosol, endoplasmic reticulum-Golgi intermediate compartment MIT domain binding, protein binding, protein domain specific binding Human UniProtKB:P54253 ISX UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q2M1V0 Intestine-specific homeobox protein 20130413 {GO:0043565=IEA, GO:0003700=IEA, GO:0005634=IEA, GO:0006351=IEA} transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0191 ISY1 HPA UniProtKB {GO:0000398=PMID:11991638, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0071013=PMID:11991638} Q9ULR0 Pre-mRNA-splicing factor ISY1 homolog protein 20101115 {GO:0000398=IC, GO:0005730=IDA, GO:0005634=IDA, GO:0071013=IDA} mRNA splicing, via spliceosome catalytic step 2 spliceosome, nucleolus, nucleus NOT Human ISYNA1 Reactome UniProtKB {GO:0006021=GO_REF:0000041, GO:0043647=Reactome:REACT_150352, GO:0004512=Reactome:REACT_150300, GO:0044281=Reactome:REACT_111217, GO:0008654=GO_REF:0000037, GO:0005829=Reactome:REACT_150300} Q9NPH2 Inositol-3-phosphate synthase 1 protein 20111102 {GO:0006021=IEA, GO:0043647=TAS, GO:0004512=TAS, GO:0044281=TAS, GO:0008654=IEA, GO:0005829=TAS} inositol biosynthetic process, inositol phosphate metabolic process, phospholipid biosynthetic process, small molecule metabolic process cytosol inositol-3-phosphate synthase activity Human ITCH HPA UniProtKB {GO:0005515=PMID:20818436, GO:0035519=PMID:17028573, GO:0006511=PMID:15678106, GO:0050687=PMID:19881509, GO:0004842=Reactome:REACT_118581, GO:0045732=GO_REF:0000019, GO:0016567=PMID:17592138, GO:0005886=PMID:14602072, GO:0090085=GO_REF:0000024, GO:0070423=Reactome:REACT_75776, GO:0005634=GO_REF:0000033, GO:0046718=PMID:12450395, GO:0001558=PMID:9462742, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_118690, GO:0005737=GO_REF:0000052, GO:0051607=GO_REF:0000037, GO:0070534=PMID:19592251, GO:0046329=GO_REF:0000024, GO:0006954=PMID:9462742, GO:0007219=Reactome:REACT_118859, GO:0042787=GO_REF:0000033, GO:0032480=Reactome:REACT_25271, GO:0005938=GO_REF:0000019, GO:0043066=PMID:20068034, GO:0046642=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0032088=GO_REF:0000024, GO:0031410=GO_REF:0000019, GO:0045236=PMID:19116316, GO:0045087=Reactome:REACT_6802, GO:0002669=GO_REF:0000019, GO:0043021=PMID:19881509, GO:0070936=PMID:19881509} Q96J02 E3 ubiquitin-protein ligase Itchy homolog protein 20090616 {GO:0005515=IPI, GO:0035519=IDA, GO:0006511=IDA, GO:0050687=IMP, GO:0004842=TAS, GO:0045732=IEA, GO:0016567=IDA, GO:0005886=IDA, GO:0090085=ISS, GO:0070423=TAS, GO:0005634=IBA, GO:0046718=TAS, GO:0001558=NAS, GO:0035872=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0051607=IEA, GO:0070534=IDA, GO:0046329=ISS, GO:0006954=NAS, GO:0007219=TAS, GO:0042787=IBA, GO:0032480=TAS, GO:0005938=IEA, GO:0043066=IMP, GO:0046642=IEA, GO:0006915=IEA, GO:0032088=ISS, GO:0031410=IEA, GO:0045236=IPI, GO:0045087=TAS, GO:0002669=IEA, GO:0043021=IPI, GO:0070936=IDA} Notch signaling pathway, apoptotic process, defense response to virus, inflammatory response, innate immune response, negative regulation of JNK cascade, negative regulation of NF-kappaB transcription factor activity, negative regulation of alpha-beta T cell proliferation, negative regulation of apoptotic process, negative regulation of defense response to virus, negative regulation of type I interferon production, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, nucleotide-binding oligomerization domain containing signaling pathway, positive regulation of T cell anergy, positive regulation of protein catabolic process, protein K29-linked ubiquitination, protein K48-linked ubiquitination, protein K63-linked ubiquitination, protein ubiquitination, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, regulation of cell growth, regulation of protein deubiquitination, ubiquitin-dependent protein catabolic process, viral entry into host cell cell cortex, cytoplasm, cytoplasmic vesicle, cytosol, nucleus, plasma membrane CXCR chemokine receptor binding, protein binding, ribonucleoprotein complex binding, ubiquitin-protein ligase activity Human ITFG1 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q8TB96 T-cell immunomodulatory protein protein 20130413 {GO:0005576=IEA, GO:0016021=IEA} extracellular region, integral to membrane Human UniProtKB-SubCell:SL-0243 ITFG2 null null {} null null null null {} null null null ITFG3 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9H0X4 Protein ITFG3 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 ITGA1 Reactome UniProtKB {GO:0005515=PMID:16754661, GO:0008305=PMID:8428973, GO:0043005=GO_REF:0000019, GO:0005886=Reactome:REACT_20663, GO:0046982=GO_REF:0000019, GO:0001669=GO_REF:0000019, GO:0005518=PMID:8428973, GO:0030593=GO_REF:0000019, GO:0045178=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0000187=GO_REF:0000019, GO:0043525=GO_REF:0000019, GO:0006936=Reactome:REACT_20558, GO:0005178=GO_REF:0000019, GO:0007160=GO_REF:0000029, GO:0007411=Reactome:REACT_18266, GO:0007229=GO_REF:0000037, GO:0042311=GO_REF:0000019, GO:0045123=GO_REF:0000019, GO:0043204=GO_REF:0000019, GO:0045121=GO_REF:0000019, GO:0009897=GO_REF:0000019} P56199 Integrin alpha-1 protein 20080310 {GO:0005515=IPI, GO:0008305=TAS, GO:0043005=IEA, GO:0005886=TAS, GO:0046982=IEA, GO:0001669=IEA, GO:0005518=TAS, GO:0030593=IEA, GO:0045178=IEA, GO:0046872=IEA, GO:0000187=IEA, GO:0043525=IEA, GO:0006936=TAS, GO:0005178=IEA, GO:0007160=NAS, GO:0007411=TAS, GO:0007229=IEA, GO:0042311=IEA, GO:0045123=IEA, GO:0043204=IEA, GO:0045121=IEA, GO:0009897=IEA} activation of MAPK activity, axon guidance, cell-matrix adhesion, cellular extravasation, integrin-mediated signaling pathway, muscle contraction, neutrophil chemotaxis, positive regulation of neuron apoptotic process, vasodilation acrosomal vesicle, basal part of cell, external side of plasma membrane, integrin complex, membrane raft, neuron projection, perikaryon, plasma membrane collagen binding, integrin binding, metal ion binding, protein binding, protein heterodimerization activity Human ITGA10 Reactome UniProtKB {GO:0008305=GO_REF:0000002, GO:0005886=Reactome:REACT_13784, GO:0007160=PMID:9685391, GO:0007229=GO_REF:0000037, GO:0005518=PMID:9685391, GO:0007155=GO_REF:0000038, GO:0046872=GO_REF:0000037} O75578 Integrin alpha-10 protein 20080310 {GO:0008305=IEA, GO:0005886=TAS, GO:0007160=TAS, GO:0007229=IEA, GO:0005518=TAS, GO:0007155=IEA, GO:0046872=IEA} cell adhesion, cell-matrix adhesion, integrin-mediated signaling pathway integrin complex, plasma membrane collagen binding, metal ion binding Human ITGA11 Reactome UniProtKB {GO:0008305=GO_REF:0000002, GO:0007517=PMID:10464311, GO:0005886=Reactome:REACT_13663, GO:0007160=PMID:10464311, GO:0007229=GO_REF:0000037, GO:0005518=PMID:10464311, GO:0007155=PMID:10486209, GO:0046872=GO_REF:0000037} Q9UKX5 Integrin alpha-11 protein 20080310 {GO:0008305=IEA, GO:0007517=TAS, GO:0005886=TAS, GO:0007160=TAS, GO:0007229=IEA, GO:0005518=TAS, GO:0007155=TAS, GO:0046872=IEA} cell adhesion, cell-matrix adhesion, integrin-mediated signaling pathway, muscle organ development integrin complex, plasma membrane collagen binding, metal ion binding Human ITGA2 BHF-UCL UniProtKB {GO:0005515=PMID:21947080, GO:0008305=GO_REF:0000002, GO:0009986=PMID:21310825, GO:0005886=PMID:21310825, GO:0005518=PMID:9391074, GO:0045178=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0007160=PMID:2545729, GO:0007596=Reactome:REACT_604, GO:0007229=GO_REF:0000037, GO:0007411=Reactome:REACT_18266, GO:0019048=GO_REF:0000037, GO:0009887=PMID:9391074, GO:0007155=PMID:10942362, GO:0009897=GO_REF:0000019} P17301 Integrin alpha-2 protein 20110427 {GO:0005515=IPI, GO:0008305=IEA, GO:0009986=IDA, GO:0005886=IDA, GO:0005518=TAS, GO:0045178=IEA, GO:0046872=IEA, GO:0007160=TAS, GO:0007596=TAS, GO:0007229=IEA, GO:0007411=TAS, GO:0019048=IEA, GO:0009887=TAS, GO:0007155=TAS, GO:0009897=IEA} axon guidance, blood coagulation, cell adhesion, cell-matrix adhesion, integrin-mediated signaling pathway, organ morphogenesis, virus-host interaction basal part of cell, cell surface, external side of plasma membrane, integrin complex, plasma membrane collagen binding, metal ion binding, protein binding Human ITGA2B IntAct UniProtKB {GO:0005515=PMID:15379538, GO:0008305=GO_REF:0000002, GO:0005886=Reactome:REACT_24004, GO:0050840=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0046872=GO_REF:0000037, GO:0042802=PMID:15067009, GO:0007160=GO_REF:0000019, GO:0007229=GO_REF:0000037, GO:0005887=PMID:2439501, GO:0007411=Reactome:REACT_18266, GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0031092=Reactome:REACT_21394, GO:0007155=PMID:2439501, GO:0005925=GO_REF:0000019, GO:0009897=GO_REF:0000019} P08514 Integrin alpha-IIb protein 20130415 {GO:0005515=IPI, GO:0008305=IEA, GO:0005886=TAS, GO:0050840=IEA, GO:0030168=TAS, GO:0046872=IEA, GO:0042802=IPI, GO:0007160=IEA, GO:0007229=IEA, GO:0005887=TAS, GO:0007411=TAS, GO:0007596=TAS, GO:0002576=TAS, GO:0031092=TAS, GO:0007155=TAS, GO:0005925=IEA, GO:0009897=IEA} axon guidance, blood coagulation, cell adhesion, cell-matrix adhesion, integrin-mediated signaling pathway, platelet activation, platelet degranulation external side of plasma membrane, focal adhesion, integral to plasma membrane, integrin complex, plasma membrane, platelet alpha granule membrane extracellular matrix binding, identical protein binding, metal ion binding, protein binding Human UniProtKB:P08514 ITGA3 BHF-UCL UniProtKB {GO:0005515=PMID:1911778, GO:0008305=GO_REF:0000002, GO:0009986=PMID:21310825, GO:0005886=PMID:21310825, GO:0045202=GO_REF:0000019, GO:0050900=Reactome:REACT_12051, GO:0046872=GO_REF:0000037, GO:0016323=GO_REF:0000019, GO:0007160=PMID:1655803, GO:0007229=GO_REF:0000037, GO:0007596=Reactome:REACT_604, GO:0007613=GO_REF:0000019, GO:0007155=GO_REF:0000002, GO:0001764=GO_REF:0000019} P26006 Integrin alpha-3 protein 20080926 {GO:0005515=IPI, GO:0008305=IEA, GO:0009986=IDA, GO:0005886=IDA, GO:0045202=IEA, GO:0050900=TAS, GO:0046872=IEA, GO:0016323=IEA, GO:0007160=TAS, GO:0007229=IEA, GO:0007596=TAS, GO:0007613=IEA, GO:0007155=IEA, GO:0001764=IEA} blood coagulation, cell adhesion, cell-matrix adhesion, integrin-mediated signaling pathway, leukocyte migration, memory, neuron migration basolateral plasma membrane, cell surface, integrin complex, plasma membrane, synapse metal ion binding, protein binding Human UniProtKB:P27797 ITGA4 BHF-UCL UniProtKB {GO:0005515=PMID:20159608, GO:0008305=GO_REF:0000002, GO:0060710=GO_REF:0000019, GO:0009986=PMID:1715889, GO:0005886=Reactome:REACT_13818, GO:0050900=Reactome:REACT_12051, GO:0046872=GO_REF:0000037, GO:0007507=GO_REF:0000019, GO:0016477=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0007229=GO_REF:0000037, GO:0001974=GO_REF:0000019, GO:0030183=PMID:1715889, GO:0050776=Reactome:REACT_11152, GO:0060324=GO_REF:0000019, GO:0007159=PMID:1715889, GO:0001968=GO_REF:0000019, GO:0007157=GO_REF:0000019, GO:0009897=GO_REF:0000019} P13612 Integrin alpha-4 protein 20080623 {GO:0005515=IPI, GO:0008305=IEA, GO:0060710=IEA, GO:0009986=IDA, GO:0005886=TAS, GO:0050900=TAS, GO:0046872=IEA, GO:0007507=IEA, GO:0016477=IEA, GO:0007596=TAS, GO:0007229=IEA, GO:0001974=IEA, GO:0030183=IC, GO:0050776=TAS, GO:0060324=IEA, GO:0007159=IDA, GO:0001968=IEA, GO:0007157=IEA, GO:0009897=IEA} B cell differentiation, blood coagulation, blood vessel remodeling, cell migration, chorio-allantoic fusion, face development, heart development, heterophilic cell-cell adhesion, integrin-mediated signaling pathway, leukocyte cell-cell adhesion, leukocyte migration, regulation of immune response cell surface, external side of plasma membrane, integrin complex, plasma membrane fibronectin binding, metal ion binding, protein binding Human GO:0007159 ITGA5 BHF-UCL UniProtKB {GO:0005515=PMID:14970227, GO:0030949=PMID:19267251, GO:0035313=PMID:14970227, GO:0005886=Reactome:REACT_160128, GO:0050731=PMID:10022831, GO:0045202=GO_REF:0000019, GO:0050900=Reactome:REACT_12051, GO:0046872=GO_REF:0000037, GO:0005911=PMID:14970227, GO:0007411=Reactome:REACT_18266, GO:0030198=Reactome:REACT_118779, GO:0007159=GO_REF:0000019, GO:0007613=GO_REF:0000019, GO:0007155=PMID:2454952, GO:0007157=GO_REF:0000019, GO:0008305=GO_REF:0000002, GO:0032587=PMID:14970227, GO:0033631=GO_REF:0000019, GO:0001525=PMID:19267251, GO:0005161=PMID:19267251, GO:0001726=PMID:11919189, GO:0005178=GO_REF:0000019, GO:0007229=GO_REF:0000037, GO:0007596=Reactome:REACT_604, GO:0019048=GO_REF:0000037, GO:0071062=PMID:19267251, GO:0007044=GO_REF:0000019, GO:0043184=PMID:19267251, GO:0005925=PMID:14970227, GO:0009897=GO_REF:0000019} P08648 Integrin alpha-5 protein 20100325 {GO:0005515=IPI, GO:0030949=TAS, GO:0035313=IEP, GO:0005886=TAS, GO:0050731=IMP, GO:0045202=IEA, GO:0050900=TAS, GO:0046872=IEA, GO:0005911=IDA, GO:0007411=TAS, GO:0030198=TAS, GO:0007159=IEA, GO:0007613=IEA, GO:0007155=TAS, GO:0007157=IEA, GO:0008305=IEA, GO:0032587=IDA, GO:0033631=IEA, GO:0001525=TAS, GO:0005161=TAS, GO:0001726=TAS, GO:0005178=IEA, GO:0007229=IEA, GO:0007596=TAS, GO:0019048=IEA, GO:0071062=TAS, GO:0007044=IEA, GO:0043184=TAS, GO:0005925=IDA, GO:0009897=IEA} angiogenesis, axon guidance, blood coagulation, cell adhesion, cell-cell adhesion mediated by integrin, cell-substrate junction assembly, extracellular matrix organization, heterophilic cell-cell adhesion, integrin-mediated signaling pathway, leukocyte cell-cell adhesion, leukocyte migration, memory, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of vascular endothelial growth factor receptor signaling pathway, virus-host interaction, wound healing, spreading of epidermal cells alphav-beta3 integrin-vitronectin complex, cell-cell junction, external side of plasma membrane, focal adhesion, integrin complex, plasma membrane, ruffle, ruffle membrane, synapse integrin binding, metal ion binding, platelet-derived growth factor receptor binding, protein binding, vascular endothelial growth factor receptor 2 binding Human ITGA6 BHF-UCL UniProtKB {GO:0030056=GO_REF:0000019, GO:0033627=GO_REF:0000019, GO:0005886=PMID:21310825, GO:0050900=Reactome:REACT_12051, GO:0046872=GO_REF:0000037, GO:0009925=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0045944=PMID:21310825, GO:0031668=GO_REF:0000019, GO:0031581=Reactome:REACT_20537, GO:0042475=GO_REF:0000019, GO:0046847=GO_REF:0000019, GO:0007155=GO_REF:0000037, GO:0008305=GO_REF:0000002, GO:0043066=PMID:21310825, GO:0022409=GO_REF:0000019, GO:0043065=PMID:19364818, GO:0034329=Reactome:REACT_20676, GO:0005604=GO_REF:0000019, GO:0005178=GO_REF:0000019, GO:0007160=GO_REF:0000019, GO:0007229=GO_REF:0000037, GO:0050873=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0007044=PMID:9185503, GO:0009897=GO_REF:0000019, GO:0042327=PMID:21310825} P23229 Integrin alpha-6 protein 20110427 {GO:0030056=IEA, GO:0033627=IEA, GO:0005886=IDA, GO:0050900=TAS, GO:0046872=IEA, GO:0009925=IEA, GO:0030198=TAS, GO:0045944=IMP, GO:0031668=IEA, GO:0031581=TAS, GO:0042475=IEA, GO:0046847=IEA, GO:0007155=IEA, GO:0008305=IEA, GO:0043066=IMP, GO:0022409=IEA, GO:0043065=IGI, GO:0034329=TAS, GO:0005604=IEA, GO:0005178=IEA, GO:0007160=IEA, GO:0007229=IEA, GO:0050873=IEA, GO:0007596=TAS, GO:0007044=TAS, GO:0009897=IEA, GO:0042327=IMP} blood coagulation, brown fat cell differentiation, cell adhesion, cell adhesion mediated by integrin, cell junction assembly, cell-matrix adhesion, cell-substrate junction assembly, cellular response to extracellular stimulus, extracellular matrix organization, filopodium assembly, hemidesmosome assembly, integrin-mediated signaling pathway, leukocyte migration, negative regulation of apoptotic process, odontogenesis of dentin-containing tooth, positive regulation of apoptotic process, positive regulation of cell-cell adhesion, positive regulation of phosphorylation, positive regulation of transcription from RNA polymerase II promoter basal plasma membrane, basement membrane, external side of plasma membrane, hemidesmosome, integrin complex, plasma membrane integrin binding, metal ion binding Human ITGA7 Reactome UniProtKB {GO:0008305=GO_REF:0000019, GO:0005886=Reactome:REACT_13716, GO:0009986=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0008360=GO_REF:0000037, GO:0048514=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005737=GO_REF:0000019, GO:0007517=PMID:9354797, GO:0005178=GO_REF:0000019, GO:0007160=PMID:9354797, GO:0016477=GO_REF:0000019, GO:0007229=GO_REF:0000019, GO:0007519=GO_REF:0000019, GO:0043236=GO_REF:0000019, GO:0007155=GO_REF:0000038, GO:0050839=GO_REF:0000019} Q13683 Integrin alpha-7 protein 20080310 {GO:0008305=IEA, GO:0005886=TAS, GO:0009986=IEA, GO:0046982=IEA, GO:0008360=IEA, GO:0048514=IEA, GO:0046872=IEA, GO:0005737=IEA, GO:0007517=TAS, GO:0005178=IEA, GO:0007160=TAS, GO:0016477=IEA, GO:0007229=IEA, GO:0007519=IEA, GO:0043236=IEA, GO:0007155=IEA, GO:0050839=IEA} blood vessel morphogenesis, cell adhesion, cell migration, cell-matrix adhesion, integrin-mediated signaling pathway, muscle organ development, regulation of cell shape, skeletal muscle tissue development cell surface, cytoplasm, integrin complex, plasma membrane cell adhesion molecule binding, integrin binding, laminin binding, metal ion binding, protein heterodimerization activity Human ITGA8 BHF-UCL UniProtKB {GO:0001656=GO_REF:0000019, GO:0008305=PMID:7768999, GO:0042472=GO_REF:0000019, GO:0005886=Reactome:REACT_150434, GO:2000721=GO_REF:0000019, GO:0045177=GO_REF:0000019, GO:0034678=PMID:21335239, GO:0046872=GO_REF:0000037, GO:0007399=GO_REF:0000037, GO:0045184=GO_REF:0000019, GO:0016337=PMID:7768999, GO:0007160=PMID:7768999, GO:0030198=Reactome:REACT_118779, GO:0007229=GO_REF:0000037, GO:0048745=GO_REF:0000019, GO:0030030=GO_REF:0000019, GO:0007613=GO_REF:0000019, GO:0030511=GO_REF:0000019} P53708 Integrin alpha-8 protein 20120105 {GO:0001656=IEA, GO:0008305=TAS, GO:0042472=IEA, GO:0005886=TAS, GO:2000721=IEA, GO:0045177=IEA, GO:0034678=TAS, GO:0046872=IEA, GO:0007399=IEA, GO:0045184=IEA, GO:0016337=NAS, GO:0007160=NAS, GO:0030198=TAS, GO:0007229=IEA, GO:0048745=IEA, GO:0030030=IEA, GO:0007613=IEA, GO:0030511=IEA} cell projection organization, cell-cell adhesion, cell-matrix adhesion, establishment of protein localization, extracellular matrix organization, inner ear morphogenesis, integrin-mediated signaling pathway, memory, metanephros development, nervous system development, positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation, positive regulation of transforming growth factor beta receptor signaling pathway, smooth muscle tissue development alpha8-beta1 integrin complex, apical part of cell, integrin complex, plasma membrane metal ion binding Human ITGA9 Reactome UniProtKB {GO:0008305=GO_REF:0000002, GO:0009925=GO_REF:0000019, GO:0005886=Reactome:REACT_22152, GO:0007411=Reactome:REACT_18266, GO:0007229=GO_REF:0000037, GO:0030593=GO_REF:0000019, GO:0007155=PMID:21060781, GO:0046872=GO_REF:0000037} Q13797 Integrin alpha-9 protein 20130301 {GO:0008305=IEA, GO:0009925=IEA, GO:0005886=TAS, GO:0007411=TAS, GO:0007229=IEA, GO:0030593=IEA, GO:0007155=IGI, GO:0046872=IEA} axon guidance, cell adhesion, integrin-mediated signaling pathway, neutrophil chemotaxis basal plasma membrane, integrin complex, plasma membrane metal ion binding Human ITGAD Reactome UniProtKB {GO:0008305=PMID:20187620, GO:0016337=GO_REF:0000029, GO:0006955=PMID:9841932, GO:0005886=Reactome:REACT_13787, GO:0007160=GO_REF:0000029, GO:0007229=GO_REF:0000037, GO:0050798=GO_REF:0000019, GO:0046872=GO_REF:0000037} Q13349 Integrin alpha-D protein 20080310 {GO:0008305=TAS, GO:0016337=NAS, GO:0006955=NAS, GO:0005886=TAS, GO:0007160=NAS, GO:0007229=IEA, GO:0050798=IEA, GO:0046872=IEA} activated T cell proliferation, cell-cell adhesion, cell-matrix adhesion, immune response, integrin-mediated signaling pathway integrin complex, plasma membrane metal ion binding Human ITGAE Reactome UniProtKB {GO:0008305=GO_REF:0000002, GO:0005886=Reactome:REACT_13535, GO:0007229=GO_REF:0000037, GO:0007155=GO_REF:0000037, GO:0009897=GO_REF:0000019, GO:0046872=GO_REF:0000037} P38570 Integrin alpha-E protein 20080418 {GO:0008305=IEA, GO:0005886=TAS, GO:0007229=IEA, GO:0007155=IEA, GO:0009897=IEA, GO:0046872=IEA} cell adhesion, integrin-mediated signaling pathway external side of plasma membrane, integrin complex, plasma membrane metal ion binding Human ITGAL BHF-UCL UniProtKB {GO:0001772=GO_REF:0000019, GO:0008305=PMID:8103515, GO:0022409=GO_REF:0000019, GO:0005886=Reactome:REACT_12042, GO:0006928=PMID:10477596, GO:0050900=Reactome:REACT_12051, GO:0046872=GO_REF:0000037, GO:0050850=GO_REF:0000019, GO:0007165=PMID:8103515, GO:0006954=PMID:8103515, GO:0007596=Reactome:REACT_604, GO:0007229=GO_REF:0000037, GO:0002291=PMID:2477710, GO:0050776=Reactome:REACT_11152, GO:0042102=GO_REF:0000019, GO:0007159=PMID:2477710, GO:0050798=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0007155=PMID:8103515, GO:0050839=PMID:1448173, GO:0007157=PMID:2477710, GO:0007166=GO_REF:0000019, GO:0009897=GO_REF:0000019} P20701 Integrin alpha-L protein 20081128 {GO:0001772=IEA, GO:0008305=NAS, GO:0022409=IEA, GO:0005886=TAS, GO:0006928=TAS, GO:0050900=TAS, GO:0046872=IEA, GO:0050850=IEA, GO:0007165=NAS, GO:0006954=NAS, GO:0007596=TAS, GO:0007229=IEA, GO:0002291=IMP, GO:0050776=TAS, GO:0042102=IEA, GO:0007159=IMP, GO:0050798=IEA, GO:0016021=IEA, GO:0007155=NAS, GO:0050839=IPI, GO:0007157=IMP, GO:0007166=IEA, GO:0009897=IEA} T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell, activated T cell proliferation, blood coagulation, cell adhesion, cell surface receptor signaling pathway, cellular component movement, heterophilic cell-cell adhesion, inflammatory response, integrin-mediated signaling pathway, leukocyte cell-cell adhesion, leukocyte migration, positive regulation of T cell proliferation, positive regulation of calcium-mediated signaling, positive regulation of cell-cell adhesion, regulation of immune response, signal transduction external side of plasma membrane, immunological synapse, integral to membrane, integrin complex, plasma membrane cell adhesion molecule binding, metal ion binding Human UniProtKB:P32942 ITGAM Reactome UniProtKB {GO:0005515=PMID:15194813, GO:0008305=GO_REF:0000002, GO:0034142=Reactome:REACT_6894, GO:0005886=Reactome:REACT_150423, GO:0030593=GO_REF:0000019, GO:0001846=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0043395=GO_REF:0000019, GO:0014005=GO_REF:0000019, GO:0050900=Reactome:REACT_12051, GO:0002224=Reactome:REACT_6966, GO:0046872=GO_REF:0000037, GO:0001948=PMID:15004192, GO:0007596=Reactome:REACT_604, GO:0007229=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0007159=GO_REF:0000019, GO:0045123=GO_REF:0000019, GO:0050798=GO_REF:0000019, GO:0007155=PMID:2563162, GO:0008201=GO_REF:0000019, GO:0009897=GO_REF:0000019} P11215 Integrin alpha-M protein 20071111 {GO:0005515=IPI, GO:0008305=IEA, GO:0034142=TAS, GO:0005886=TAS, GO:0030593=IEA, GO:0001846=IEA, GO:0005634=IEA, GO:0043395=IEA, GO:0014005=IEA, GO:0050900=TAS, GO:0002224=TAS, GO:0046872=IEA, GO:0001948=IPI, GO:0007596=TAS, GO:0007229=IEA, GO:0045087=TAS, GO:0007159=IEA, GO:0045123=IEA, GO:0050798=IEA, GO:0007155=TAS, GO:0008201=IEA, GO:0009897=IEA} activated T cell proliferation, blood coagulation, cell adhesion, cellular extravasation, innate immune response, integrin-mediated signaling pathway, leukocyte cell-cell adhesion, leukocyte migration, microglia development, neutrophil chemotaxis, toll-like receptor 4 signaling pathway, toll-like receptor signaling pathway external side of plasma membrane, integrin complex, nucleus, plasma membrane glycoprotein binding, heparan sulfate proteoglycan binding, heparin binding, metal ion binding, opsonin binding, protein binding Human ITGAV BHF-UCL UniProtKB {GO:0005515=PMID:20639902, GO:0002474=Reactome:REACT_75820, GO:0008284=PMID:19578119, GO:0005886=PMID:21310825, GO:2000536=PMID:10570297, GO:0031994=PMID:19578119, GO:0046718=PMID:10570297, GO:0050900=Reactome:REACT_12051, GO:0046872=GO_REF:0000037, GO:0050764=PMID:10570297, GO:0035867=PMID:19578119, GO:0030198=Reactome:REACT_118779, GO:0007411=Reactome:REACT_18266, GO:0005080=GO_REF:0000024, GO:0052066=PMID:10570297, GO:0007155=PMID:10218736, GO:0070371=GO_REF:0000024, GO:0033690=GO_REF:0000019, GO:0008305=PMID:15215180, GO:0043066=PMID:10708943, GO:0050431=GO_REF:0000024, GO:0030335=GO_REF:0000019, GO:0009986=PMID:21310825, GO:0005245=PMID:18395422, GO:0010745=PMID:15215180, GO:0042590=Reactome:REACT_111119, GO:0043277=GO_REF:0000019, GO:0001846=GO_REF:0000024, GO:0045715=PMID:15215180, GO:2000425=GO_REF:0000024, GO:0001525=PMID:11866539, GO:0050748=PMID:15215180, GO:0010888=PMID:15215180, GO:0045785=PMID:10708943, GO:0045335=Reactome:REACT_111116, GO:0016020=GO_REF:0000024, GO:0007160=PMID:11877390, GO:0007229=PMID:11877390, GO:0005887=PMID:11877390, GO:0007596=Reactome:REACT_604, GO:0070588=PMID:18395422, GO:0032369=PMID:15215180, GO:0002479=Reactome:REACT_111174, GO:0009897=GO_REF:0000019} P06756 Integrin alpha-V protein 20110328 {GO:0005515=IPI, GO:0002474=TAS, GO:0008284=IDA, GO:0005886=IDA, GO:2000536=IDA, GO:0031994=IDA, GO:0046718=TAS, GO:0050900=TAS, GO:0046872=IEA, GO:0050764=IDA, GO:0035867=IDA, GO:0030198=TAS, GO:0007411=TAS, GO:0005080=ISS, GO:0052066=NAS, GO:0007155=IDA, GO:0070371=ISS, GO:0033690=IEA, GO:0008305=IDA, GO:0043066=IDA, GO:0050431=ISS, GO:0030335=IEA, GO:0009986=IDA, GO:0005245=IDA, GO:0010745=IMP, GO:0042590=TAS, GO:0043277=IEA, GO:0001846=ISS, GO:0045715=IMP, GO:2000425=ISS, GO:0001525=IEP, GO:0050748=IMP, GO:0010888=IMP, GO:0045785=IDA, GO:0045335=TAS, GO:0016020=ISS, GO:0007160=NAS, GO:0007229=NAS, GO:0005887=NAS, GO:0007596=TAS, GO:0070588=IDA, GO:0032369=IMP, GO:0002479=TAS, GO:0009897=IEA} ERK1 and ERK2 cascade, angiogenesis, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic cell clearance, axon guidance, blood coagulation, calcium ion transmembrane transport, cell adhesion, cell-matrix adhesion, entry of symbiont into host cell by promotion of host phagocytosis, extracellular matrix organization, integrin-mediated signaling pathway, leukocyte migration, negative regulation of apoptotic process, negative regulation of entry of bacterium into host cell, negative regulation of lipid storage, negative regulation of lipid transport, negative regulation of lipoprotein metabolic process, negative regulation of low-density lipoprotein particle receptor biosynthetic process, negative regulation of macrophage derived foam cell differentiation, positive regulation of cell adhesion, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of osteoblast proliferation, regulation of apoptotic cell clearance, regulation of phagocytosis, viral entry into host cell alphav-beta3 integrin-IGF-1-IGF1R complex, cell surface, external side of plasma membrane, integral to plasma membrane, integrin complex, membrane, phagocytic vesicle, plasma membrane insulin-like growth factor I binding, metal ion binding, opsonin binding, protein binding, protein kinase C binding, transforming growth factor beta binding, voltage-gated calcium channel activity Human ITGAX BHF-UCL UniProtKB {GO:0005515=PMID:17726152, GO:0008305=GO_REF:0000002, GO:0051607=GO_REF:0000019, GO:0005886=Reactome:REACT_13612, GO:0007596=Reactome:REACT_604, GO:0007229=GO_REF:0000037, GO:0009887=PMID:3327687, GO:0004872=PMID:2303426, GO:0050900=Reactome:REACT_12051, GO:0007155=GO_REF:0000037, GO:0009897=GO_REF:0000019, GO:0046872=GO_REF:0000037} P20702 Integrin alpha-X protein 20071123 {GO:0005515=IPI, GO:0008305=IEA, GO:0051607=IEA, GO:0005886=TAS, GO:0007596=TAS, GO:0007229=IEA, GO:0009887=TAS, GO:0004872=TAS, GO:0050900=TAS, GO:0007155=IEA, GO:0009897=IEA, GO:0046872=IEA} blood coagulation, cell adhesion, defense response to virus, integrin-mediated signaling pathway, leukocyte migration, organ morphogenesis external side of plasma membrane, integrin complex, plasma membrane metal ion binding, protein binding, receptor activity Human UniProtKB:Q5JRA6 ITGB1 ENSEMBL UniProtKB {GO:0005515=PMID:14970227, GO:0030056=GO_REF:0000019, GO:0031594=GO_REF:0000019, GO:0005518=GO_REF:0000019, GO:0050731=GO_REF:0000019, GO:0050900=Reactome:REACT_12051, GO:0002020=GO_REF:0000019, GO:0071305=GO_REF:0000019, GO:0031175=GO_REF:0000019, GO:0001948=GO_REF:0000019, GO:0070830=GO_REF:0000019, GO:0001894=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0007411=Reactome:REACT_18266, GO:0055007=GO_REF:0000019, GO:0035748=GO_REF:0000019, GO:0042470=GO_REF:0000039, GO:0008305=PMID:9552005, GO:0030335=GO_REF:0000019, GO:0009986=PMID:1715889, GO:0046982=PMID:9552005, GO:0001708=GO_REF:0000019, GO:0019901=GO_REF:0000019, GO:0034329=Reactome:REACT_20676, GO:0060135=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0045214=GO_REF:0000019, GO:0007275=GO_REF:0000002, GO:0034678=PMID:21335239, GO:0001701=GO_REF:0000019, GO:0034679=GO_REF:0000019, GO:0071479=GO_REF:0000019, GO:0005604=GO_REF:0000019, GO:0005178=GO_REF:0000019, GO:0008277=GO_REF:0000019, GO:0051393=GO_REF:0000019, GO:0007229=GO_REF:0000019, GO:0031345=GO_REF:0000019, GO:0050776=Reactome:REACT_11152, GO:0010976=GO_REF:0000019, GO:0043236=GO_REF:0000019, GO:0045121=GO_REF:0000019, GO:0005925=GO_REF:0000019, GO:0009897=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0005886=PMID:21310825, GO:0010811=GO_REF:0000019, GO:0002042=GO_REF:0000019, GO:0032154=GO_REF:0000039, GO:0046872=GO_REF:0000037, GO:0045807=GO_REF:0000019, GO:0034667=GO_REF:0000019, GO:0000082=GO_REF:0000019, GO:0014704=GO_REF:0000019, GO:0030183=PMID:1715889, GO:0007159=PMID:1715889, GO:0051726=GO_REF:0000019, GO:0004872=GO_REF:0000002, GO:0001968=GO_REF:0000019, GO:0007156=PMID:10201960, GO:0071559=GO_REF:0000019, GO:0014823=GO_REF:0000019, GO:0042277=GO_REF:0000019, GO:0008354=GO_REF:0000019, GO:0043065=PMID:19364818, GO:0001669=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0006874=GO_REF:0000019, GO:0032587=PMID:14970227, GO:0003779=GO_REF:0000019, GO:0033631=PMID:17704059, GO:0001726=PMID:11919189, GO:0034698=GO_REF:0000019, GO:0042383=GO_REF:0000019, GO:0006968=PMID:10201960, GO:0016477=PMID:11919189, GO:0007160=GO_REF:0000019, GO:0045665=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0007161=PMID:19651211, GO:0045666=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0032594=GO_REF:0000019, GO:0071260=GO_REF:0000019, GO:0043410=GO_REF:0000019} Q5T3E6 Integrin beta-1 protein 20130413 {GO:0005515=IPI, GO:0030056=IEA, GO:0031594=IEA, GO:0005518=IEA, GO:0050731=IEA, GO:0050900=TAS, GO:0002020=IEA, GO:0071305=IEA, GO:0031175=IEA, GO:0001948=IEA, GO:0070830=IEA, GO:0001894=IEA, GO:0030198=TAS, GO:0007411=TAS, GO:0055007=IEA, GO:0035748=IEA, GO:0042470=IEA, GO:0008305=NAS, GO:0030335=IEA, GO:0009986=IDA, GO:0046982=NAS, GO:0001708=IEA, GO:0019901=IEA, GO:0034329=TAS, GO:0060135=IEA, GO:0019904=IEA, GO:0045214=IEA, GO:0007275=IEA, GO:0034678=TAS, GO:0001701=IEA, GO:0034679=IEA, GO:0071479=IEA, GO:0005604=IEA, GO:0005178=IEA, GO:0008277=IEA, GO:0051393=IEA, GO:0007229=IEA, GO:0031345=IEA, GO:0050776=TAS, GO:0010976=IEA, GO:0043236=IEA, GO:0045121=IEA, GO:0005925=IEA, GO:0009897=IEA, GO:0008284=IEA, GO:0008285=IEA, GO:0005886=IDA, GO:0010811=IEA, GO:0002042=IEA, GO:0032154=IEA, GO:0046872=IEA, GO:0045807=IEA, GO:0034667=IEA, GO:0000082=IEA, GO:0014704=IEA, GO:0030183=IC, GO:0007159=IDA, GO:0051726=IEA, GO:0004872=IEA, GO:0001968=IEA, GO:0007156=TAS, GO:0071559=IEA, GO:0014823=IEA, GO:0042277=IEA, GO:0008354=IEA, GO:0043065=IGI, GO:0001669=IEA, GO:0042493=IEA, GO:0006874=IEA, GO:0032587=IDA, GO:0003779=IEA, GO:0033631=IEP, GO:0001726=TAS, GO:0034698=IEA, GO:0042383=IEA, GO:0006968=TAS, GO:0016477=TAS, GO:0007160=IEA, GO:0045665=IEA, GO:0007596=TAS, GO:0007161=IGI, GO:0045666=IEA, GO:0019048=IEA, GO:0032594=IEA, GO:0071260=IEA, GO:0043410=IEA} B cell differentiation, G1/S transition of mitotic cell cycle, axon guidance, blood coagulation, calcium-independent cell-matrix adhesion, cardiac muscle cell differentiation, cell fate specification, cell junction assembly, cell migration, cell migration involved in sprouting angiogenesis, cell-cell adhesion mediated by integrin, cell-matrix adhesion, cellular calcium ion homeostasis, cellular defense response, cellular response to ionizing radiation, cellular response to mechanical stimulus, cellular response to vitamin D, extracellular matrix organization, germ cell migration, homophilic cell adhesion, in utero embryonic development, integrin-mediated signaling pathway, leukocyte cell-cell adhesion, leukocyte migration, maternal process involved in female pregnancy, multicellular organismal development, negative regulation of cell projection organization, negative regulation of cell proliferation, negative regulation of neuron differentiation, neuron projection development, positive regulation of MAPK cascade, positive regulation of apoptotic process, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of cell-substrate adhesion, positive regulation of endocytosis, positive regulation of neuron differentiation, positive regulation of neuron projection development, positive regulation of peptidyl-tyrosine phosphorylation, protein transport within lipid bilayer, regulation of G-protein coupled receptor protein signaling pathway, regulation of cell cycle, regulation of immune response, response to activity, response to drug, response to gonadotropin stimulus, response to transforming growth factor beta stimulus, sarcomere organization, tight junction assembly, tissue homeostasis, virus-host interaction acrosomal vesicle, alpha3-beta1 integrin complex, alpha8-beta1 integrin complex, alpha9-beta1 integrin complex, basement membrane, cell surface, cleavage furrow, external side of plasma membrane, focal adhesion, hemidesmosome, integrin complex, intercalated disc, melanosome, membrane raft, myelin sheath abaxonal region, neuromuscular junction, plasma membrane, ruffle, ruffle membrane, sarcolemma actin binding, alpha-actinin binding, collagen binding, fibronectin binding, glycoprotein binding, integrin binding, laminin binding, metal ion binding, peptide binding, protease binding, protein binding, protein domain specific binding, protein heterodimerization activity, protein kinase binding, receptor activity Human Ensembl:ENSRNOP00000014785 ITGB1BP1 HGNC UniProtKB {GO:0005515=PMID:11919189, GO:0016477=PMID:11919189, GO:0007160=PMID:9281591, GO:0016020=PMID:9281591, GO:0007229=GO_REF:0000038, GO:0001726=PMID:11919189, GO:0030027=PMID:11919189, GO:0007243=PMID:9813144, GO:0005829=PMID:11919189} O14713 Integrin beta-1-binding protein 1 protein 20070418 {GO:0005515=IPI, GO:0016477=TAS, GO:0007160=IDA, GO:0016020=NAS, GO:0007229=IEA, GO:0001726=IDA, GO:0030027=IDA, GO:0007243=TAS, GO:0005829=IDA} cell migration, cell-matrix adhesion, integrin-mediated signaling pathway, intracellular protein kinase cascade cytosol, lamellipodium, membrane, ruffle protein binding Human ITGB1BP2 PINC UniProtKB {GO:0007165=PMID:10506186, GO:0030018=GO_REF:0000019, GO:0017124=GO_REF:0000037, GO:0007517=PMID:10506186, GO:0005178=GO_REF:0000019, GO:0005509=GO_REF:0000019, GO:0008270=GO_REF:0000019} Q9UKP3 Integrin beta-1-binding protein 2 protein 20030904 {GO:0007165=TAS, GO:0030018=IEA, GO:0017124=IEA, GO:0007517=TAS, GO:0005178=IEA, GO:0005509=IEA, GO:0008270=IEA} muscle organ development, signal transduction Z disc SH3 domain binding, calcium ion binding, integrin binding, zinc ion binding Human ITGB2 BHF-UCL UniProtKB {GO:0008305=PMID:12885943, GO:0034142=Reactome:REACT_6894, GO:0005886=Reactome:REACT_150423, GO:0019901=PMID:12885943, GO:0050730=PMID:12885943, GO:0008360=PMID:12885943, GO:0030593=PMID:12885943, GO:0007267=PMID:12885943, GO:0006915=PMID:12885943, GO:0007275=GO_REF:0000002, GO:0050900=Reactome:REACT_12051, GO:0002224=Reactome:REACT_6966, GO:0046872=GO_REF:0000037, GO:0001948=PMID:16831868, GO:0006954=PMID:12885943, GO:0007160=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0007229=PMID:12885943, GO:0045087=Reactome:REACT_6802, GO:0050776=Reactome:REACT_11152, GO:0007159=PMID:12885943, GO:0004872=GO_REF:0000002, GO:0007155=PMID:1694220} P05107 Integrin beta-2 protein 20081127 {GO:0008305=NAS, GO:0034142=TAS, GO:0005886=TAS, GO:0019901=IPI, GO:0050730=IDA, GO:0008360=NAS, GO:0030593=IDA, GO:0007267=NAS, GO:0006915=NAS, GO:0007275=IEA, GO:0050900=TAS, GO:0002224=TAS, GO:0046872=IEA, GO:0001948=IPI, GO:0006954=NAS, GO:0007160=IEA, GO:0007596=TAS, GO:0007229=NAS, GO:0045087=TAS, GO:0050776=TAS, GO:0007159=IDA, GO:0004872=IEA, GO:0007155=TAS} apoptotic process, blood coagulation, cell adhesion, cell-cell signaling, cell-matrix adhesion, inflammatory response, innate immune response, integrin-mediated signaling pathway, leukocyte cell-cell adhesion, leukocyte migration, multicellular organismal development, neutrophil chemotaxis, regulation of cell shape, regulation of immune response, regulation of peptidyl-tyrosine phosphorylation, toll-like receptor 4 signaling pathway, toll-like receptor signaling pathway integrin complex, plasma membrane glycoprotein binding, metal ion binding, protein kinase binding, receptor activity Human UniProtKB:Q15762 ITGB3 GOC UniProtKB {GO:0005515=PMID:20639902, GO:0030949=PMID:19267251, GO:0005886=Reactome:REACT_150434, GO:0045124=PMID:19267251, GO:0050731=PMID:10022831, GO:0005634=PMID:22027834, GO:0050900=Reactome:REACT_12051, GO:0042802=PMID:14681217, GO:0032147=PMID:10022831, GO:0006457=PMID:15466936, GO:0007411=Reactome:REACT_18266, GO:0030198=Reactome:REACT_118779, GO:0031092=Reactome:REACT_21394, GO:0004872=GO_REF:0000002, GO:0007155=PMID:2452834, GO:0050839=PMID:8837777, GO:0030334=GO_REF:0000002, GO:0008305=PMID:15215180, GO:0042470=PMID:15466936, GO:0010745=PMID:15215180, GO:0060055=PMID:19267251, GO:0014909=PMID:8837777, GO:0030168=Reactome:REACT_798, GO:0003756=PMID:15466936, GO:0045715=PMID:15215180, GO:0005161=PMID:19267251, GO:0050748=PMID:15215180, GO:0010888=PMID:15215180, GO:0010595=PMID:10022831, GO:0070527=PMID:15466936, GO:0001938=PMID:10022831, GO:0007160=GO_REF:0000002, GO:0005887=PMID:2452834, GO:0007596=Reactome:REACT_604, GO:0007229=PMID:21488147, GO:0019048=GO_REF:0000037, GO:0042060=PMID:8837777, GO:0071062=PMID:19267251, GO:0002576=Reactome:REACT_318, GO:0001934=PMID:19267251, GO:0032369=PMID:15215180, GO:0035295=PMID:19267251, GO:0043184=PMID:10022831, GO:0007044=GO_REF:0000002} P05106 Integrin beta-3 protein 20130413 {GO:0005515=IPI, GO:0030949=TAS, GO:0005886=TAS, GO:0045124=TAS, GO:0050731=IMP, GO:0005634=IDA, GO:0050900=TAS, GO:0042802=IPI, GO:0032147=IMP, GO:0006457=IDA, GO:0007411=TAS, GO:0030198=TAS, GO:0031092=TAS, GO:0004872=IEA, GO:0007155=TAS, GO:0050839=IPI, GO:0030334=IEA, GO:0008305=IDA, GO:0042470=IDA, GO:0010745=IMP, GO:0060055=TAS, GO:0014909=IMP, GO:0030168=TAS, GO:0003756=IDA, GO:0045715=IMP, GO:0005161=TAS, GO:0050748=IMP, GO:0010888=IMP, GO:0010595=IMP, GO:0070527=IMP, GO:0001938=IMP, GO:0007160=IEA, GO:0005887=TAS, GO:0007596=TAS, GO:0007229=TAS, GO:0019048=IEA, GO:0042060=IC, GO:0071062=TAS, GO:0002576=TAS, GO:0001934=TAS, GO:0032369=IMP, GO:0035295=TAS, GO:0043184=IPI, GO:0007044=IEA} activation of protein kinase activity, angiogenesis involved in wound healing, axon guidance, blood coagulation, cell adhesion, cell-matrix adhesion, cell-substrate junction assembly, extracellular matrix organization, integrin-mediated signaling pathway, leukocyte migration, negative regulation of lipid storage, negative regulation of lipid transport, negative regulation of lipoprotein metabolic process, negative regulation of low-density lipoprotein particle receptor biosynthetic process, negative regulation of macrophage derived foam cell differentiation, platelet activation, platelet aggregation, platelet degranulation, positive regulation of endothelial cell migration, positive regulation of endothelial cell proliferation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of protein phosphorylation, positive regulation of vascular endothelial growth factor receptor signaling pathway, protein folding, regulation of bone resorption, regulation of cell migration, smooth muscle cell migration, tube development, virus-host interaction, wound healing alphav-beta3 integrin-vitronectin complex, integral to plasma membrane, integrin complex, melanosome, nucleus, plasma membrane, platelet alpha granule membrane cell adhesion molecule binding, identical protein binding, platelet-derived growth factor receptor binding, protein binding, protein disulfide isomerase activity, receptor activity, vascular endothelial growth factor receptor 2 binding Human ITGB3BP HPA UniProtKB {GO:0000236=Reactome:REACT_682, GO:0048011=Reactome:REACT_13776, GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0006334=Reactome:REACT_22344, GO:0006915=Reactome:REACT_13643, GO:0005634=GO_REF:0000052, GO:0008022=PMID:10490654, GO:0097190=Reactome:REACT_13720, GO:0006351=GO_REF:0000037, GO:0005829=Reactome:REACT_150414, GO:0034080=Reactome:REACT_22186, GO:0007165=PMID:7593198, GO:0005737=PMID:7593198, GO:0016020=PMID:7593198, GO:0000087=Reactome:REACT_910, GO:0000777=GO_REF:0000039, GO:0005654=Reactome:REACT_22217, GO:0004871=PMID:10490654, GO:0000278=Reactome:REACT_152, GO:0007155=PMID:7593198, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q13352 Centromere protein R protein 20100326 {GO:0000236=TAS, GO:0048011=TAS, GO:0006355=IEA, GO:0005730=IDA, GO:0006334=TAS, GO:0006915=TAS, GO:0005634=IDA, GO:0008022=TAS, GO:0097190=TAS, GO:0006351=IEA, GO:0005829=TAS, GO:0034080=TAS, GO:0007165=TAS, GO:0005737=TAS, GO:0016020=TAS, GO:0000087=TAS, GO:0000777=IEA, GO:0005654=TAS, GO:0004871=TAS, GO:0000278=TAS, GO:0007155=TAS, GO:0000090=TAS, GO:0051301=IEA} CENP-A containing nucleosome assembly at centromere, M phase of mitotic cell cycle, apoptotic process, apoptotic signaling pathway, cell adhesion, cell division, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, neurotrophin TRK receptor signaling pathway, nucleosome assembly, regulation of transcription, DNA-dependent, signal transduction, transcription, DNA-dependent condensed chromosome kinetochore, cytoplasm, cytosol, membrane, nucleolus, nucleoplasm, nucleus protein C-terminus binding, signal transducer activity NOT Human ITGB4 BHF-UCL UniProtKB {GO:0005515=PMID:21880726, GO:0008305=GO_REF:0000019, GO:0030056=PMID:12482924, GO:0009986=PMID:21310825, GO:0005886=PMID:21310825, GO:0034329=Reactome:REACT_20676, GO:0009611=PMID:19403692, GO:0007275=GO_REF:0000002, GO:0005604=GO_REF:0000019, GO:0009925=GO_REF:0000019, GO:0007160=GO_REF:0000002, GO:0030198=Reactome:REACT_118779, GO:0007229=GO_REF:0000037, GO:0048870=PMID:19403692, GO:0031581=Reactome:REACT_20537, GO:0004872=GO_REF:0000002, GO:0046847=GO_REF:0000019, GO:0007155=PMID:2311577, GO:0031252=PMID:19403692} P16144 Integrin beta-4 protein 20110427 {GO:0005515=IPI, GO:0008305=IEA, GO:0030056=IDA, GO:0009986=IDA, GO:0005886=IDA, GO:0034329=TAS, GO:0009611=IDA, GO:0007275=IEA, GO:0005604=IEA, GO:0009925=IEA, GO:0007160=IEA, GO:0030198=TAS, GO:0007229=IEA, GO:0048870=IMP, GO:0031581=TAS, GO:0004872=IEA, GO:0046847=IEA, GO:0007155=NAS, GO:0031252=IDA} cell adhesion, cell junction assembly, cell motility, cell-matrix adhesion, extracellular matrix organization, filopodium assembly, hemidesmosome assembly, integrin-mediated signaling pathway, multicellular organismal development, response to wounding basal plasma membrane, basement membrane, cell leading edge, cell surface, hemidesmosome, integrin complex, plasma membrane protein binding, receptor activity Human ITGB5 IntAct UniProtKB {GO:0005515=PMID:21397862, GO:0008305=GO_REF:0000002, GO:0002474=Reactome:REACT_75820, GO:0005886=Reactome:REACT_150434, GO:0042590=Reactome:REACT_111119, GO:0007275=GO_REF:0000002, GO:0045335=Reactome:REACT_111116, GO:0005178=GO_REF:0000019, GO:0006936=Reactome:REACT_20558, GO:0007229=GO_REF:0000037, GO:0030198=Reactome:REACT_118779, GO:0002479=Reactome:REACT_111174, GO:0004872=GO_REF:0000002, GO:0007155=GO_REF:0000037, GO:0005925=GO_REF:0000019, GO:0031252=GO_REF:0000019} P18084 Integrin beta-5 protein 20130415 {GO:0005515=IPI, GO:0008305=IEA, GO:0002474=TAS, GO:0005886=TAS, GO:0042590=TAS, GO:0007275=IEA, GO:0045335=TAS, GO:0005178=IEA, GO:0006936=TAS, GO:0007229=IEA, GO:0030198=TAS, GO:0002479=TAS, GO:0004872=IEA, GO:0007155=IEA, GO:0005925=IEA, GO:0031252=IEA} antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, cell adhesion, extracellular matrix organization, integrin-mediated signaling pathway, multicellular organismal development, muscle contraction cell leading edge, focal adhesion, integrin complex, phagocytic vesicle, plasma membrane integrin binding, protein binding, receptor activity Human UniProtKB:Q9BY76 ITGB6 Reactome UniProtKB {GO:0008305=GO_REF:0000002, GO:0006954=GO_REF:0000019, GO:0005178=GO_REF:0000019, GO:0005886=Reactome:REACT_150434, GO:0007160=GO_REF:0000002, GO:0030198=Reactome:REACT_118779, GO:0007229=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0007275=GO_REF:0000002, GO:0004872=GO_REF:0000002, GO:0007155=PMID:2365683} P18564 Integrin beta-6 protein 20130301 {GO:0008305=IEA, GO:0006954=IEA, GO:0005178=IEA, GO:0005886=TAS, GO:0007160=IEA, GO:0030198=TAS, GO:0007229=IEA, GO:0019048=IEA, GO:0007275=IEA, GO:0004872=IEA, GO:0007155=TAS} cell adhesion, cell-matrix adhesion, extracellular matrix organization, inflammatory response, integrin-mediated signaling pathway, multicellular organismal development, virus-host interaction integrin complex, plasma membrane integrin binding, receptor activity Human ITGB7 Reactome UniProtKB {GO:0008305=GO_REF:0000002, GO:0005886=Reactome:REACT_13535, GO:0007160=GO_REF:0000002, GO:0007229=GO_REF:0000037, GO:0050776=Reactome:REACT_11152, GO:0007275=GO_REF:0000002, GO:0004872=GO_REF:0000002, GO:0007155=PMID:2040616, GO:0050900=GO_REF:0000019, GO:0046872=GO_REF:0000037} P26010 Integrin beta-7 protein 20130130 {GO:0008305=IEA, GO:0005886=TAS, GO:0007160=IEA, GO:0007229=IEA, GO:0050776=TAS, GO:0007275=IEA, GO:0004872=IEA, GO:0007155=TAS, GO:0050900=IEA, GO:0046872=IEA} cell adhesion, cell-matrix adhesion, integrin-mediated signaling pathway, leukocyte migration, multicellular organismal development, regulation of immune response integrin complex, plasma membrane metal ion binding, receptor activity Human ITGB8 BHF-UCL UniProtKB {GO:0008305=GO_REF:0000002, GO:0060674=PMID:19267251, GO:0005886=Reactome:REACT_150434, GO:0007160=GO_REF:0000002, GO:0030198=Reactome:REACT_118779, GO:0007229=GO_REF:0000037, GO:0001573=GO_REF:0000019, GO:0004872=GO_REF:0000002, GO:0007155=PMID:1918072} P26012 Integrin beta-8 protein 20100325 {GO:0008305=IEA, GO:0060674=TAS, GO:0005886=TAS, GO:0007160=IEA, GO:0030198=TAS, GO:0007229=IEA, GO:0001573=IEA, GO:0004872=IEA, GO:0007155=TAS} cell adhesion, cell-matrix adhesion, extracellular matrix organization, ganglioside metabolic process, integrin-mediated signaling pathway, placenta blood vessel development integrin complex, plasma membrane receptor activity Human ITIH1 PINC UniProtKB {GO:0045321=GO_REF:0000029, GO:0004867=GO_REF:0000037, GO:0005509=PMID:2446322, GO:0030212=GO_REF:0000029, GO:0005576=PMID:14718574} P19827 Inter-alpha-trypsin inhibitor heavy chain H1 protein 20030904 {GO:0045321=NAS, GO:0004867=IEA, GO:0005509=TAS, GO:0030212=NAS, GO:0005576=NAS} hyaluronan metabolic process, leukocyte activation extracellular region calcium ion binding, serine-type endopeptidase inhibitor activity Human ITIH2 InterPro UniProtKB {GO:0010951=PMID:2476436, GO:0004866=PMID:2476436, GO:0004867=GO_REF:0000002, GO:0030212=GO_REF:0000002, GO:0005576=PMID:14718574} Q5T985 Uncharacterized protein protein 20130413 {GO:0010951=TAS, GO:0004866=TAS, GO:0004867=IEA, GO:0030212=IEA, GO:0005576=NAS} hyaluronan metabolic process, negative regulation of endopeptidase activity extracellular region endopeptidase inhibitor activity, serine-type endopeptidase inhibitor activity Human InterPro:IPR010600 ITIH3 GOC UniProtKB {GO:0010951=PMID:2465147, GO:0004866=PMID:2465147, GO:0004867=GO_REF:0000037, GO:0030212=GO_REF:0000002, GO:0005576=PMID:14718574} Q06033 Inter-alpha-trypsin inhibitor heavy chain H3 protein 20130413 {GO:0010951=TAS, GO:0004866=TAS, GO:0004867=IEA, GO:0030212=IEA, GO:0005576=NAS} hyaluronan metabolic process, negative regulation of endopeptidase activity extracellular region endopeptidase inhibitor activity, serine-type endopeptidase inhibitor activity Human ITIH4 GOC UniProtKB {GO:0010951=PMID:9756925, GO:0005515=PMID:16271702, GO:0005737=GO_REF:0000019, GO:0004866=PMID:9756925, GO:0005886=GO_REF:0000019, GO:0004867=GO_REF:0000037, GO:0030212=GO_REF:0000002, GO:0005576=PMID:14718574, GO:0006953=PMID:19263524, GO:0034097=PMID:10486281} Q14624 Inter-alpha-trypsin inhibitor heavy chain H4 protein 20130413 {GO:0010951=TAS, GO:0005515=IPI, GO:0005737=IEA, GO:0004866=TAS, GO:0005886=IEA, GO:0004867=IEA, GO:0030212=IEA, GO:0005576=NAS, GO:0006953=IEP, GO:0034097=IEP} acute-phase response, hyaluronan metabolic process, negative regulation of endopeptidase activity, response to cytokine stimulus cytoplasm, extracellular region, plasma membrane endopeptidase inhibitor activity, protein binding, serine-type endopeptidase inhibitor activity Human ITIH5 UniProtKB UniProtKB {GO:0004867=GO_REF:0000037, GO:0030212=GO_REF:0000002, GO:0005576=GO_REF:0000039} Q86UX2 Inter-alpha-trypsin inhibitor heavy chain H5 protein 20130413 {GO:0004867=IEA, GO:0030212=IEA, GO:0005576=IEA} hyaluronan metabolic process extracellular region serine-type endopeptidase inhibitor activity Human UniProtKB-SubCell:SL-0243 ITK IntAct UniProtKB {GO:0005515=PMID:19807924, GO:0050852=Reactome:REACT_12526, GO:0007202=GO_REF:0000024, GO:0001816=GO_REF:0000024, GO:0001865=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_12604, GO:0035556=GO_REF:0000002, GO:0002250=GO_REF:0000024, GO:0007165=PMID:8364206, GO:0006968=PMID:8364206, GO:0042110=PMID:12186560, GO:0005543=GO_REF:0000002, GO:0032609=GO_REF:0000019, GO:0032633=GO_REF:0000019, GO:0004715=PMID:12186560} Q08881 Tyrosine-protein kinase ITK/TSK protein 20130415 {GO:0005515=IPI, GO:0050852=TAS, GO:0007202=ISS, GO:0001816=ISS, GO:0001865=IEA, GO:0005524=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0035556=IEA, GO:0002250=ISS, GO:0007165=TAS, GO:0006968=TAS, GO:0042110=TAS, GO:0005543=IEA, GO:0032609=IEA, GO:0032633=IEA, GO:0004715=IDA} NK T cell differentiation, T cell activation, T cell receptor signaling pathway, activation of phospholipase C activity, adaptive immune response, cellular defense response, cytokine production, interferon-gamma production, interleukin-4 production, intracellular signal transduction, signal transduction cytosol ATP binding, metal ion binding, non-membrane spanning protein tyrosine kinase activity, phospholipid binding, protein binding Human UniProtKB:P48023 ITLN1 UniProtKB UniProtKB {GO:0046326=PMID:16531507, GO:0001934=PMID:16531507, GO:0045121=GO_REF:0000024, GO:0005576=GO_REF:0000039, GO:0031526=GO_REF:0000024, GO:0031225=GO_REF:0000037, GO:0009624=GO_REF:0000024} Q8WWA0 Intelectin-1 protein 20071210 {GO:0046326=IDA, GO:0001934=IDA, GO:0045121=ISS, GO:0005576=IEA, GO:0031526=ISS, GO:0031225=IEA, GO:0009624=ISS} positive regulation of glucose import, positive regulation of protein phosphorylation, response to nematode anchored to membrane, brush border membrane, extracellular region, membrane raft Human ITM2A IntAct UniProtKB {GO:0005515=PMID:15983050, GO:0016021=GO_REF:0000037} O43736 Integral membrane protein 2A protein 20130415 {GO:0005515=IPI, GO:0016021=IEA} integral to membrane protein binding Human UniProtKB:P05067-4 ITM2B HPA UniProtKB {GO:0005515=PMID:17965014, GO:0005794=GO_REF:0000052, GO:0005886=PMID:22194595, GO:0006915=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0005576=Reactome:REACT_75905, GO:0006917=GO_REF:0000019, GO:0005524=GO_REF:0000019, GO:0005615=PMID:18524908, GO:0042985=PMID:16027166, GO:0043231=GO_REF:0000052, GO:0007399=PMID:10391242, GO:0001540=PMID:19849849, GO:0031301=PMID:10526337, GO:0030660=PMID:17965014, GO:0010008=GO_REF:0000039} Q9Y287 Integral membrane protein 2B protein 20101115 {GO:0005515=IPI, GO:0005794=IDA, GO:0005886=IDA, GO:0006915=IEA, GO:0005634=IDA, GO:0005576=TAS, GO:0006917=IEA, GO:0005524=IEA, GO:0005615=IDA, GO:0042985=IDA, GO:0043231=IDA, GO:0007399=TAS, GO:0001540=IPI, GO:0031301=IDA, GO:0030660=IDA, GO:0010008=IEA} apoptotic process, induction of apoptosis, negative regulation of amyloid precursor protein biosynthetic process, nervous system development Golgi apparatus, Golgi-associated vesicle membrane, endosome membrane, extracellular region, extracellular space, integral to organelle membrane, intracellular membrane-bounded organelle, nucleus, plasma membrane ATP binding, beta-amyloid binding, protein binding Human ITM2C BHF-UCL UniProtKB {GO:0005515=PMID:18452648, GO:0048471=PMID:18452648, GO:0001540=PMID:19849849, GO:0005794=GO_REF:0000054, GO:0005886=PMID:19114711, GO:0030182=PMID:18452648, GO:0010977=PMID:18452648, GO:0016021=GO_REF:0000037, GO:0005765=GO_REF:0000039, GO:0012502=GO_REF:0000019, GO:0005764=PMID:14592447, GO:0005524=GO_REF:0000019} Q9NQX7 Integral membrane protein 2C protein 20091223 {GO:0005515=IPI, GO:0048471=IDA, GO:0001540=IPI, GO:0005794=IDA, GO:0005886=IDA, GO:0030182=IDA, GO:0010977=IDA, GO:0016021=IEA, GO:0005765=IEA, GO:0012502=IEA, GO:0005764=IDA, GO:0005524=IEA} induction of programmed cell death, negative regulation of neuron projection development, neuron differentiation Golgi apparatus, integral to membrane, lysosomal membrane, lysosome, perinuclear region of cytoplasm, plasma membrane ATP binding, beta-amyloid binding, protein binding Human UniProtKB:P05067 ITPA HPA UniProtKB {GO:0036220=Reactome:REACT_150277, GO:0005737=GO_REF:0000052, GO:0051276=GO_REF:0000019, GO:0006193=GO_REF:0000019, GO:0000166=GO_REF:0000037, GO:0036222=Reactome:REACT_150195, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0035870=Reactome:REACT_150247, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_150277} Q9BY32 Inosine triphosphate pyrophosphatase protein 20100326 {GO:0036220=EXP, GO:0005737=IDA, GO:0051276=IEA, GO:0006193=IEA, GO:0000166=IEA, GO:0036222=EXP, GO:0055086=TAS, GO:0044281=TAS, GO:0035870=EXP, GO:0046872=IEA, GO:0005829=TAS} ITP catabolic process, chromosome organization, nucleobase-containing small molecule metabolic process, small molecule metabolic process cytoplasm, cytosol ITP diphosphatase activity, XTP diphosphatase activity, dITP diphosphatase activity, metal ion binding, nucleotide binding Human ITPK1 Reactome UniProtKB {GO:0052835=Reactome:REACT_150431, GO:0052825=Reactome:REACT_150330, GO:0000287=GO_REF:0000002, GO:0043647=Reactome:REACT_150312, GO:0052725=Reactome:REACT_150157, GO:0044281=Reactome:REACT_111217, GO:0003824=PMID:8662638, GO:0005524=GO_REF:0000037, GO:0052831=Reactome:REACT_150200, GO:0052830=Reactome:REACT_150351, GO:0052726=Reactome:REACT_150236, GO:0005829=Reactome:REACT_150431, GO:0005622=GO_REF:0000002, GO:0007165=PMID:8662638, GO:0032957=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0016853=GO_REF:0000037, GO:0047325=Reactome:REACT_150321} Q13572 Inositol-tetrakisphosphate 1-kinase protein 20111213 {GO:0052835=TAS, GO:0052825=TAS, GO:0000287=IEA, GO:0043647=TAS, GO:0052725=TAS, GO:0044281=TAS, GO:0003824=TAS, GO:0005524=IEA, GO:0052831=TAS, GO:0052830=TAS, GO:0052726=TAS, GO:0005829=TAS, GO:0005622=IEA, GO:0007165=TAS, GO:0032957=IEA, GO:0007596=TAS, GO:0016853=IEA, GO:0047325=TAS} blood coagulation, inositol phosphate metabolic process, inositol trisphosphate metabolic process, signal transduction, small molecule metabolic process cytosol, intracellular ATP binding, catalytic activity, inositol tetrakisphosphate 1-kinase activity, inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity, inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity, inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity, inositol-1,3,4-trisphosphate 5-kinase activity, inositol-1,3,4-trisphosphate 6-kinase activity, inositol-3,4,6-trisphosphate 1-kinase activity, isomerase activity, magnesium ion binding Human ITPKA Reactome UniProtKB {GO:0007165=PMID:1847047, GO:0005516=GO_REF:0000037, GO:0006020=GO_REF:0000019, GO:0008440=GO_REF:0000003, GO:0043647=Reactome:REACT_150312, GO:0044281=Reactome:REACT_111217, GO:0004683=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_150282} P23677 Inositol-trisphosphate 3-kinase A protein 20111102 {GO:0007165=TAS, GO:0005516=IEA, GO:0006020=IEA, GO:0008440=IEA, GO:0043647=TAS, GO:0044281=TAS, GO:0004683=IEA, GO:0005524=IEA, GO:0005829=TAS} inositol metabolic process, inositol phosphate metabolic process, signal transduction, small molecule metabolic process cytosol ATP binding, calmodulin binding, calmodulin-dependent protein kinase activity, inositol-1,4,5-trisphosphate 3-kinase activity Human ITPKB Reactome UniProtKB {GO:0046638=GO_REF:0000019, GO:0007165=PMID:1654894, GO:0005516=GO_REF:0000037, GO:0008440=GO_REF:0000003, GO:0043647=Reactome:REACT_150312, GO:0000165=GO_REF:0000019, GO:0046579=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0045059=GO_REF:0000019, GO:0007166=GO_REF:0000019, GO:0005829=Reactome:REACT_150282} P27987 Inositol-trisphosphate 3-kinase B protein 20111102 {GO:0046638=IEA, GO:0007165=TAS, GO:0005516=IEA, GO:0008440=IEA, GO:0043647=TAS, GO:0000165=IEA, GO:0046579=IEA, GO:0044281=TAS, GO:0005524=IEA, GO:0045059=IEA, GO:0007166=IEA, GO:0005829=TAS} MAPK cascade, cell surface receptor signaling pathway, inositol phosphate metabolic process, positive regulation of Ras protein signal transduction, positive regulation of alpha-beta T cell differentiation, positive thymic T cell selection, signal transduction, small molecule metabolic process cytosol ATP binding, calmodulin binding, inositol-1,4,5-trisphosphate 3-kinase activity Human ITPKC Reactome UniProtKB {GO:0005516=GO_REF:0000037, GO:0008440=GO_REF:0000003, GO:0043647=Reactome:REACT_150312, GO:0005634=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_150282} Q96DU7 Inositol-trisphosphate 3-kinase C protein 20111213 {GO:0005516=IEA, GO:0008440=IEA, GO:0043647=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0005524=IEA, GO:0005829=TAS} inositol phosphate metabolic process, small molecule metabolic process cytosol, nucleus ATP binding, calmodulin binding, inositol-1,4,5-trisphosphate 3-kinase activity Human ITPR1 GOC UniProtKB {GO:0005515=PMID:20010695, GO:0031088=PMID:10828023, GO:0005783=PMID:8648241, GO:0005637=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0007202=Reactome:REACT_12079, GO:0009791=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0050882=GO_REF:0000019, GO:0006816=PMID:7852357, GO:0031094=PMID:10828023, GO:0031095=Reactome:REACT_118637, GO:0005955=GO_REF:0000019, GO:0001666=PMID:19120137, GO:0048011=Reactome:REACT_11061, GO:0051209=GO_REF:0000024, GO:0005220=GO_REF:0000024, GO:0048016=PMID:8648241, GO:0032469=GO_REF:0000019, GO:0005730=GO_REF:0000019, GO:0015085=PMID:7500840, GO:0030168=Reactome:REACT_798, GO:0014069=GO_REF:0000019, GO:0007165=Reactome:REACT_12478, GO:0016529=GO_REF:0000019, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0070059=GO_REF:0000024, GO:0007596=Reactome:REACT_604, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0005789=Reactome:REACT_118808, GO:0016021=GO_REF:0000037, GO:0035091=GO_REF:0000024, GO:0038096=Reactome:REACT_160123, GO:0005218=GO_REF:0000024} Q14643 Inositol 1,4,5-trisphosphate receptor type 1 protein 20130413 {GO:0005515=IPI, GO:0031088=IDA, GO:0005783=NAS, GO:0005637=IEA, GO:0044281=TAS, GO:0007202=TAS, GO:0009791=IEA, GO:0007173=TAS, GO:0050882=IEA, GO:0006816=NAS, GO:0031094=IDA, GO:0031095=TAS, GO:0005955=IEA, GO:0001666=IDA, GO:0048011=TAS, GO:0051209=ISS, GO:0005220=ISS, GO:0048016=TAS, GO:0032469=IEA, GO:0005730=IEA, GO:0015085=TAS, GO:0030168=TAS, GO:0014069=IEA, GO:0007165=TAS, GO:0016529=IEA, GO:0006112=TAS, GO:0050796=TAS, GO:0070059=ISS, GO:0007596=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0005789=TAS, GO:0016021=IEA, GO:0035091=ISS, GO:0038096=TAS, GO:0005218=ISS} Fc-gamma receptor signaling pathway involved in phagocytosis, activation of phospholipase C activity, blood coagulation, calcium ion transport, endoplasmic reticulum calcium ion homeostasis, energy reserve metabolic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, inositol phosphate-mediated signaling, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, neurotrophin TRK receptor signaling pathway, platelet activation, post-embryonic development, regulation of insulin secretion, release of sequestered calcium ion into cytosol, response to hypoxia, signal transduction, small molecule metabolic process, voluntary musculoskeletal movement calcineurin complex, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, nuclear inner membrane, nucleolus, platelet dense granule membrane, platelet dense tubular network, platelet dense tubular network membrane, postsynaptic density, sarcoplasmic reticulum calcium ion transmembrane transporter activity, inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity, intracellular ligand-gated calcium channel activity, phosphatidylinositol binding, protein binding Human ITPR2 BHF-UCL UniProtKB {GO:0005886=PMID:10828023, GO:0007202=Reactome:REACT_12079, GO:0044281=Reactome:REACT_111217, GO:0007173=Reactome:REACT_9417, GO:0006810=PMID:8081734, GO:0031095=Reactome:REACT_118637, GO:0005938=GO_REF:0000019, GO:0001666=PMID:19120137, GO:0048011=Reactome:REACT_11061, GO:0005220=GO_REF:0000019, GO:0015085=PMID:8081734, GO:0030168=Reactome:REACT_798, GO:0033017=PMID:10828023, GO:0007165=Reactome:REACT_12478, GO:0071361=GO_REF:0000019, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0007596=Reactome:REACT_604, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0005789=Reactome:REACT_118808, GO:0016021=GO_REF:0000037, GO:0071320=GO_REF:0000019, GO:0035091=GO_REF:0000019, GO:0038096=Reactome:REACT_160123} Q14571 Inositol 1,4,5-trisphosphate receptor type 2 protein 20120815 {GO:0005886=IDA, GO:0007202=TAS, GO:0044281=TAS, GO:0007173=TAS, GO:0006810=TAS, GO:0031095=TAS, GO:0005938=IEA, GO:0001666=IDA, GO:0048011=TAS, GO:0005220=IEA, GO:0015085=TAS, GO:0030168=TAS, GO:0033017=IMP, GO:0007165=TAS, GO:0071361=IEA, GO:0006112=TAS, GO:0050796=TAS, GO:0007596=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0005789=TAS, GO:0016021=IEA, GO:0071320=IEA, GO:0035091=IEA, GO:0038096=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, activation of phospholipase C activity, blood coagulation, cellular response to cAMP, cellular response to ethanol, energy reserve metabolic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, neurotrophin TRK receptor signaling pathway, platelet activation, regulation of insulin secretion, response to hypoxia, signal transduction, small molecule metabolic process, transport cell cortex, endoplasmic reticulum membrane, integral to membrane, plasma membrane, platelet dense tubular network membrane, sarcoplasmic reticulum membrane calcium ion transmembrane transporter activity, inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity, phosphatidylinositol binding Human ITPR3 BHF-UCL UniProtKB {GO:0005515=PMID:19052258, GO:0060402=GO_REF:0000024, GO:0005886=PMID:21062895, GO:0005783=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0007202=Reactome:REACT_12079, GO:0051291=GO_REF:0000024, GO:0007204=GO_REF:0000024, GO:0005640=GO_REF:0000024, GO:0070679=PMID:8288584, GO:0005737=GO_REF:0000024, GO:0007173=Reactome:REACT_9417, GO:0043209=GO_REF:0000024, GO:0043025=GO_REF:0000024, GO:0051260=GO_REF:0000024, GO:0031095=Reactome:REACT_118637, GO:0048011=Reactome:REACT_11061, GO:0005220=PMID:10828023, GO:0005730=GO_REF:0000019, GO:0045177=PMID:8288584, GO:0030168=Reactome:REACT_798, GO:0050916=GO_REF:0000019, GO:0050917=GO_REF:0000019, GO:0000822=GO_REF:0000024, GO:0005903=PMID:8288584, GO:0051592=PMID:19052258, GO:0007165=Reactome:REACT_12478, GO:0043533=GO_REF:0000024, GO:0050913=GO_REF:0000019, GO:0006112=Reactome:REACT_1505, GO:0007186=GO_REF:0000024, GO:0050796=Reactome:REACT_18325, GO:0005887=PMID:10828023, GO:0007596=Reactome:REACT_604, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0005789=Reactome:REACT_118808, GO:0005654=GO_REF:0000019, GO:0035091=GO_REF:0000019, GO:0038096=Reactome:REACT_160123, GO:0005218=GO_REF:0000024} Q14573 Inositol 1,4,5-trisphosphate receptor type 3 protein 20090624 {GO:0005515=IPI, GO:0060402=ISS, GO:0005886=IDA, GO:0005783=ISS, GO:0044281=TAS, GO:0007202=TAS, GO:0051291=ISS, GO:0007204=ISS, GO:0005640=ISS, GO:0070679=IDA, GO:0005737=ISS, GO:0007173=TAS, GO:0043209=ISS, GO:0043025=ISS, GO:0051260=ISS, GO:0031095=TAS, GO:0048011=TAS, GO:0005220=IDA, GO:0005730=IEA, GO:0045177=ISS, GO:0030168=TAS, GO:0050916=IEA, GO:0050917=IEA, GO:0000822=ISS, GO:0005903=ISS, GO:0051592=IDA, GO:0007165=TAS, GO:0043533=ISS, GO:0050913=IEA, GO:0006112=TAS, GO:0007186=ISS, GO:0050796=TAS, GO:0005887=IDA, GO:0007596=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0005789=TAS, GO:0005654=IEA, GO:0035091=IEA, GO:0038096=TAS, GO:0005218=ISS} Fc-gamma receptor signaling pathway involved in phagocytosis, G-protein coupled receptor signaling pathway, activation of phospholipase C activity, blood coagulation, calcium ion transport into cytosol, elevation of cytosolic calcium ion concentration, energy reserve metabolic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, neurotrophin TRK receptor signaling pathway, platelet activation, protein heterooligomerization, protein homooligomerization, regulation of insulin secretion, response to calcium ion, sensory perception of bitter taste, sensory perception of sweet taste, sensory perception of umami taste, signal transduction, small molecule metabolic process apical part of cell, brush border, cytoplasm, endoplasmic reticulum, endoplasmic reticulum membrane, integral to plasma membrane, myelin sheath, neuronal cell body, nuclear outer membrane, nucleolus, nucleoplasm, plasma membrane, platelet dense tubular network membrane inositol 1,3,4,5 tetrakisphosphate binding, inositol 1,4,5 trisphosphate binding, inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity, inositol hexakisphosphate binding, intracellular ligand-gated calcium channel activity, phosphatidylinositol binding, protein binding Human ITPRIP UniProtKB UniProtKB {GO:0005886=GO_REF:0000039} Q8IWB1 Inositol 1,4,5-trisphosphate receptor-interacting protein protein 20130413 {GO:0005886=IEA} plasma membrane Human UniProtKB-SubCell:SL-0039 ITPRIPL1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q6GPH6 Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 ITSN1 InterPro UniProtKB {GO:0005515=PMID:12812986, GO:0051897=GO_REF:0000019, GO:0043005=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000052, GO:0007264=Reactome:REACT_11044, GO:0035023=GO_REF:0000002, GO:0045202=GO_REF:0000037, GO:0030139=GO_REF:0000019, GO:0005829=Reactome:REACT_19216, GO:0005085=PMID:9799604, GO:0035556=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0043524=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0005089=GO_REF:0000002, GO:0070064=PMID:20946875, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0005509=PMID:9799604, GO:0006915=Reactome:REACT_13638, GO:0048488=PMID:9799604, GO:0097190=Reactome:REACT_13720, GO:0030027=GO_REF:0000039, GO:0006897=GO_REF:0000002, GO:0005905=PMID:20946875, GO:0019209=GO_REF:0000019, GO:0032947=PMID:20946875} Q6J334 Intersectin-1 protein 20130413 {GO:0005515=IPI, GO:0051897=IEA, GO:0043005=IEA, GO:0030054=IEA, GO:0005886=IDA, GO:0007264=TAS, GO:0035023=IEA, GO:0045202=IEA, GO:0030139=IEA, GO:0005829=TAS, GO:0005085=NAS, GO:0035556=IEA, GO:0005622=IEA, GO:0043524=IEA, GO:0005543=IEA, GO:0005089=IEA, GO:0070064=IPI, GO:0051056=TAS, GO:0048011=TAS, GO:0005509=NAS, GO:0006915=TAS, GO:0048488=TAS, GO:0097190=TAS, GO:0030027=IEA, GO:0006897=IEA, GO:0005905=IDA, GO:0019209=IEA, GO:0032947=IDA} apoptotic process, apoptotic signaling pathway, endocytosis, intracellular signal transduction, negative regulation of neuron apoptotic process, neurotrophin TRK receptor signaling pathway, positive regulation of protein kinase B signaling cascade, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction, synaptic vesicle endocytosis cell junction, coated pit, cytosol, endocytic vesicle, intracellular, lamellipodium, neuron projection, plasma membrane, synapse Rho guanyl-nucleotide exchange factor activity, calcium ion binding, guanyl-nucleotide exchange factor activity, kinase activator activity, phospholipid binding, proline-rich region binding, protein binding, protein complex scaffold Human InterPro:IPR000219 ITSN2 PINC UniProtKB {GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0035023=GO_REF:0000002, GO:0005070=PMID:9630982, GO:0005509=GO_REF:0000002, GO:0005089=GO_REF:0000002, GO:0006897=GO_REF:0000037} Q9NZM3 Intersectin-2 protein 20030904 {GO:0005737=IEA, GO:0005543=IEA, GO:0035023=IEA, GO:0005070=TAS, GO:0005509=IEA, GO:0005089=IEA, GO:0006897=IEA} endocytosis, regulation of Rho protein signal transduction cytoplasm Rho guanyl-nucleotide exchange factor activity, SH3/SH2 adaptor activity, calcium ion binding, phospholipid binding Human IVD BHF-UCL UniProtKB {GO:0034641=Reactome:REACT_13, GO:0008470=GO_REF:0000024, GO:0031966=GO_REF:0000019, GO:0005759=GO_REF:0000024, GO:0050660=GO_REF:0000002, GO:0009083=Reactome:REACT_197, GO:0003995=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0006552=GO_REF:0000024} P26440 Isovaleryl-CoA dehydrogenase, mitochondrial protein 20091127 {GO:0034641=TAS, GO:0008470=ISS, GO:0031966=IEA, GO:0005759=ISS, GO:0050660=IEA, GO:0009083=TAS, GO:0003995=IEA, GO:0044281=TAS, GO:0006552=ISS} branched-chain amino acid catabolic process, cellular nitrogen compound metabolic process, leucine catabolic process, small molecule metabolic process mitochondrial matrix, mitochondrial membrane acyl-CoA dehydrogenase activity, flavin adenine dinucleotide binding, isovaleryl-CoA dehydrogenase activity Human UniProtKB:P12007 IVL UniProtKB UniProtKB {GO:0005737=PMID:16639001, GO:0018149=PMID:10908733, GO:0010224=PMID:16639001, GO:0030216=PMID:10908733, GO:0005198=PMID:10908733, GO:0031424=GO_REF:0000037, GO:0018153=PMID:1601889, GO:0030674=PMID:10908733, GO:0001533=PMID:10908733} P07476 Involucrin protein 20060607 {GO:0005737=IDA, GO:0018149=IDA, GO:0010224=IDA, GO:0030216=IDA, GO:0005198=IDA, GO:0031424=IEA, GO:0018153=TAS, GO:0030674=IDA, GO:0001533=IDA} isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine, keratinization, keratinocyte differentiation, peptide cross-linking, response to UV-B cornified envelope, cytoplasm protein binding, bridging, structural molecule activity Human IVNS1ABP PINC UniProtKB {GO:0008380=PMID:9696811, GO:0005667=PMID:9696811, GO:0005737=GO_REF:0000039, GO:0019048=GO_REF:0000037, GO:0005681=PMID:9696811, GO:0009615=PMID:9696811, GO:0005856=GO_REF:0000039, GO:0006383=PMID:9696811} Q9Y6Y0 Influenza virus NS1A-binding protein protein 20030904 {GO:0008380=TAS, GO:0005667=TAS, GO:0005737=IEA, GO:0019048=IEA, GO:0005681=TAS, GO:0009615=TAS, GO:0005856=IEA, GO:0006383=TAS} RNA splicing, response to virus, transcription from RNA polymerase III promoter, virus-host interaction cytoplasm, cytoskeleton, spliceosomal complex, transcription factor complex Human IWS1 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000002} Q96ST2 Protein IWS1 homolog protein 20130413 {GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} transcription, DNA-dependent nucleus DNA binding Human UniProtKB-SubCell:SL-0191 JAG1 BHF-UCL UniProtKB {GO:0007220=Reactome:REACT_2001, GO:0005886=PMID:20437614, GO:0045599=GO_REF:0000019, GO:0003184=PMID:20437614, GO:0005112=PMID:9268641, GO:0003215=GO_REF:0000024, GO:0072017=GO_REF:0000019, GO:2000737=PMID:19682396, GO:0061314=PMID:20437614, GO:0045639=GO_REF:0000019, GO:0007219=Reactome:REACT_118862, GO:0042127=PMID:10329626, GO:0045944=PMID:20437614, GO:0045445=PMID:10329626, GO:0045446=PMID:10329626, GO:0097150=PMID:19682396, GO:0030334=PMID:11549580, GO:0045747=GO_REF:0000019, GO:0030097=PMID:10329626, GO:0042491=GO_REF:0000019, GO:0002011=GO_REF:0000019, GO:0001709=PMID:9207788, GO:0005509=GO_REF:0000029, GO:0060411=GO_REF:0000024, GO:0035909=GO_REF:0000024, GO:0045177=GO_REF:0000019, GO:0005576=PMID:11427524, GO:0007275=GO_REF:0000029, GO:0001525=PMID:8955070, GO:0061444=GO_REF:0000024, GO:0007399=PMID:8923452, GO:0061156=PMID:9207787, GO:0016020=PMID:9268641, GO:0045665=GO_REF:0000019, GO:0005887=PMID:11427524, GO:0072070=GO_REF:0000019, GO:0030216=PMID:12107827, GO:0005198=PMID:10679295, GO:0061309=GO_REF:0000024, GO:0032495=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0008083=PMID:11067884} P78504 Protein jagged-1 protein 20120727 {GO:0007220=TAS, GO:0005886=IDA, GO:0045599=IEA, GO:0003184=IMP, GO:0005112=NAS, GO:0003215=ISS, GO:0072017=IEA, GO:2000737=IMP, GO:0061314=IMP, GO:0045639=IEA, GO:0007219=TAS, GO:0042127=NAS, GO:0045944=IMP, GO:0045445=NAS, GO:0045446=NAS, GO:0097150=IEP, GO:0030334=NAS, GO:0045747=IEA, GO:0030097=NAS, GO:0042491=IEA, GO:0002011=IEA, GO:0001709=NAS, GO:0005509=NAS, GO:0060411=ISS, GO:0035909=ISS, GO:0045177=IEA, GO:0005576=NAS, GO:0007275=NAS, GO:0001525=NAS, GO:0061444=ISS, GO:0007399=NAS, GO:0061156=IMP, GO:0016020=TAS, GO:0045665=IEA, GO:0005887=NAS, GO:0072070=IEA, GO:0030216=NAS, GO:0005198=NAS, GO:0061309=ISS, GO:0032495=IEA, GO:0016021=IEA, GO:0008083=NAS} Notch receptor processing, Notch signaling involved in heart development, Notch signaling pathway, angiogenesis, aorta morphogenesis, auditory receptor cell differentiation, cardiac neural crest cell development involved in outflow tract morphogenesis, cardiac right ventricle morphogenesis, cardiac septum morphogenesis, cell fate determination, distal tubule development, endocardial cushion cell development, endothelial cell differentiation, hemopoiesis, keratinocyte differentiation, loop of Henle development, morphogenesis of an epithelial sheet, multicellular organismal development, myoblast differentiation, negative regulation of fat cell differentiation, negative regulation of neuron differentiation, negative regulation of stem cell differentiation, nervous system development, neuronal stem cell maintenance, positive regulation of Notch signaling pathway, positive regulation of myeloid cell differentiation, positive regulation of transcription from RNA polymerase II promoter, pulmonary artery morphogenesis, pulmonary valve morphogenesis, regulation of cell migration, regulation of cell proliferation, response to muramyl dipeptide apical part of cell, extracellular region, integral to membrane, integral to plasma membrane, membrane, plasma membrane Notch binding, calcium ion binding, growth factor activity, structural molecule activity Human UniProtKB:Q9QXX0 JAG2 IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0030334=PMID:11549580, GO:0007220=Reactome:REACT_2001, GO:0005886=Reactome:REACT_160234, GO:0042492=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0005112=PMID:9315665, GO:0042981=GO_REF:0000019, GO:0007283=PMID:11700865, GO:0001701=GO_REF:0000019, GO:0030155=GO_REF:0000019, GO:0030154=PMID:11549580, GO:0001501=GO_REF:0000019, GO:0003016=GO_REF:0000019, GO:0007049=PMID:11549580, GO:0009912=PMID:10080181, GO:0016331=GO_REF:0000019, GO:0007219=Reactome:REACT_118862, GO:0030217=PMID:10383933, GO:0005887=PMID:10910909, GO:0042127=PMID:10383933, GO:0045061=PMID:10383933, GO:0042475=GO_REF:0000019, GO:0008083=PMID:10383933} Q9Y219 Protein jagged-2 protein 20130415 {GO:0005515=IPI, GO:0030334=NAS, GO:0007220=TAS, GO:0005886=TAS, GO:0042492=IEA, GO:0005509=IEA, GO:0005112=IPI, GO:0042981=IEA, GO:0007283=IEP, GO:0001701=IEA, GO:0030155=IEA, GO:0030154=IDA, GO:0001501=IEA, GO:0003016=IEA, GO:0007049=NAS, GO:0009912=ISS, GO:0016331=IEA, GO:0007219=TAS, GO:0030217=IDA, GO:0005887=ISS, GO:0042127=IDA, GO:0045061=IDA, GO:0042475=IEA, GO:0008083=IDA} Notch receptor processing, Notch signaling pathway, T cell differentiation, auditory receptor cell fate commitment, cell cycle, cell differentiation, gamma-delta T cell differentiation, in utero embryonic development, morphogenesis of embryonic epithelium, odontogenesis of dentin-containing tooth, regulation of apoptotic process, regulation of cell adhesion, regulation of cell migration, regulation of cell proliferation, respiratory system process, skeletal system development, spermatogenesis, thymic T cell selection integral to plasma membrane, plasma membrane Notch binding, calcium ion binding, growth factor activity, protein binding Human UniProtKB:Q5VTD9 JAGN1 UniProtKB UniProtKB {GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q8N5M9 Protein jagunal homolog 1 protein 20130413 {GO:0005789=IEA, GO:0016021=IEA} endoplasmic reticulum membrane, integral to membrane Human UniProtKB-SubCell:SL-0097 JAK1 BHF-UCL UniProtKB {GO:0005515=PMID:7759950, GO:0005131=PMID:10502458, GO:0019221=Reactome:REACT_25229, GO:0005634=PMID:10502458, GO:0018108=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0007243=GO_REF:0000019, GO:0005829=Reactome:REACT_115890, GO:0012505=GO_REF:0000039, GO:0060334=Reactome:REACT_24980, GO:0035556=PMID:8232552, GO:0005737=PMID:10502458, GO:0060337=Reactome:REACT_25162, GO:0060338=Reactome:REACT_25216, GO:0016020=GO_REF:0000037, GO:0006468=PMID:1848670, GO:0004713=Reactome:REACT_25105, GO:0005856=GO_REF:0000002, GO:0004715=GO_REF:0000003, GO:0046677=PMID:16280321, GO:0060333=Reactome:REACT_25078, GO:0007167=GO_REF:0000019} P23458 Tyrosine-protein kinase JAK1 protein 20081205 {GO:0005515=IPI, GO:0005131=ISS, GO:0019221=TAS, GO:0005634=IDA, GO:0018108=IEA, GO:0005524=IEA, GO:0007243=IEA, GO:0005829=TAS, GO:0012505=IEA, GO:0060334=TAS, GO:0035556=TAS, GO:0005737=IDA, GO:0060337=TAS, GO:0060338=TAS, GO:0016020=IEA, GO:0006468=TAS, GO:0004713=TAS, GO:0005856=IEA, GO:0004715=IEA, GO:0046677=IDA, GO:0060333=TAS, GO:0007167=IEA} cytokine-mediated signaling pathway, enzyme linked receptor protein signaling pathway, interferon-gamma-mediated signaling pathway, intracellular protein kinase cascade, intracellular signal transduction, peptidyl-tyrosine phosphorylation, protein phosphorylation, regulation of interferon-gamma-mediated signaling pathway, regulation of type I interferon-mediated signaling pathway, response to antibiotic, type I interferon-mediated signaling pathway cytoplasm, cytoskeleton, cytosol, endomembrane system, membrane, nucleus ATP binding, growth hormone receptor binding, non-membrane spanning protein tyrosine kinase activity, protein binding, protein tyrosine kinase activity Human JAK2 BHF-UCL UniProtKB {GO:0042506=GO_REF:0000019, GO:0005515=PMID:18692472, GO:0042503=GO_REF:0000019, GO:0042508=GO_REF:0000019, GO:0050731=GO_REF:0000024, GO:0030154=GO_REF:0000024, GO:0060334=Reactome:REACT_24980, GO:0046777=GO_REF:0000024, GO:0033194=GO_REF:0000019, GO:0046677=PMID:16280321, GO:0060333=Reactome:REACT_25078, GO:0022408=GO_REF:0000019, GO:0032760=GO_REF:0000024, GO:0018108=GO_REF:0000024, GO:0043392=GO_REF:0000024, GO:0043388=GO_REF:0000019, GO:0042977=GO_REF:0000024, GO:0032731=GO_REF:0000019, GO:0042523=GO_REF:0000024, GO:0060399=GO_REF:0000024, GO:0005634=PMID:10502458, GO:0060396=PMID:10925297, GO:0060397=GO_REF:0000024, GO:0051428=GO_REF:0000019, GO:0016363=GO_REF:0000019, GO:0005829=Reactome:REACT_116060, GO:0042393=PMID:19783980, GO:0000186=GO_REF:0000019, GO:0051091=GO_REF:0000019, GO:0030041=PMID:10925297, GO:0031959=GO_REF:0000019, GO:0035409=PMID:19783980, GO:0042517=GO_REF:0000024, GO:0050867=GO_REF:0000019, GO:0005102=PMID:11201744, GO:0050727=PMID:10925297, GO:0033130=GO_REF:0000019, GO:0035401=PMID:19783980, GO:0097296=GO_REF:0000024, GO:0012505=GO_REF:0000039, GO:0004672=PMID:9670957, GO:0007596=Reactome:REACT_604, GO:0005901=GO_REF:0000024, GO:0050729=GO_REF:0000019, GO:0030218=GO_REF:0000024, GO:0032516=GO_REF:0000019, GO:0007498=PMID:9590174, GO:0048008=GO_REF:0000019, GO:0033160=GO_REF:0000019, GO:0045597=GO_REF:0000019, GO:0019221=PMID:8609418, GO:0043560=GO_REF:0000019, GO:0007243=GO_REF:0000024, GO:0043524=GO_REF:0000019, GO:0032496=GO_REF:0000024, GO:0030099=GO_REF:0000019, GO:0070671=PMID:7528775, GO:0032024=GO_REF:0000019, GO:0005856=GO_REF:0000002, GO:0045822=GO_REF:0000019, GO:0042169=PMID:9727029, GO:0030335=GO_REF:0000019, GO:0019901=PMID:10925297, GO:0014068=GO_REF:0000024, GO:0033209=PMID:8609418, GO:0007186=GO_REF:0000019, GO:0045121=GO_REF:0000024, GO:0043548=GO_REF:0000019, GO:0020037=PMID:21036157, GO:0007260=GO_REF:0000024, GO:0031103=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0008285=GO_REF:0000024, GO:0007262=GO_REF:0000024, GO:0005131=GO_REF:0000024, GO:0010811=PMID:10925297, GO:0006928=PMID:9670957, GO:0031702=GO_REF:0000019, GO:0007204=GO_REF:0000019, GO:0045429=GO_REF:0000019, GO:0035556=PMID:9590174, GO:0005737=PMID:10502458, GO:0035722=PMID:7528775, GO:0043065=GO_REF:0000024, GO:0005143=GO_REF:0000024, GO:0006919=GO_REF:0000024, GO:0061180=GO_REF:0000024, GO:0008631=GO_REF:0000019, GO:0006915=GO_REF:0000024, GO:0008022=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0007259=PMID:9670957, GO:0007165=GO_REF:0000024, GO:0031904=Reactome:REACT_115907, GO:0009755=GO_REF:0000019, GO:0006468=PMID:9670957, GO:0034612=PMID:8609418, GO:0004713=Reactome:REACT_25139, GO:0051770=GO_REF:0000024, GO:0004715=GO_REF:0000003, GO:0007167=GO_REF:0000024} O60674 Tyrosine-protein kinase JAK2 protein 20110401 {GO:0042506=IEA, GO:0005515=IPI, GO:0042503=IEA, GO:0042508=IEA, GO:0050731=ISS, GO:0030154=ISS, GO:0060334=TAS, GO:0046777=ISS, GO:0033194=IEA, GO:0046677=IDA, GO:0060333=TAS, GO:0022408=IEA, GO:0032760=ISS, GO:0018108=ISS, GO:0043392=ISS, GO:0043388=IEA, GO:0042977=ISS, GO:0032731=IEA, GO:0042523=ISS, GO:0060399=ISS, GO:0005634=IDA, GO:0060396=IDA, GO:0060397=ISS, GO:0051428=IEA, GO:0016363=IEA, GO:0005829=TAS, GO:0042393=IDA, GO:0000186=IEA, GO:0051091=IEA, GO:0030041=NAS, GO:0031959=IEA, GO:0035409=IDA, GO:0042517=ISS, GO:0050867=IEA, GO:0005102=IPI, GO:0050727=IDA, GO:0033130=IEA, GO:0035401=IDA, GO:0097296=ISS, GO:0012505=IEA, GO:0004672=NAS, GO:0007596=TAS, GO:0005901=ISS, GO:0050729=IEA, GO:0030218=ISS, GO:0032516=IEA, GO:0007498=TAS, GO:0048008=IEA, GO:0033160=IEA, GO:0045597=IEA, GO:0019221=IDA, GO:0043560=IEA, GO:0007243=ISS, GO:0043524=IEA, GO:0032496=ISS, GO:0030099=IEA, GO:0070671=IDA, GO:0032024=IEA, GO:0005856=IEA, GO:0045822=IEA, GO:0042169=IPI, GO:0030335=IEA, GO:0019901=IDA, GO:0014068=ISS, GO:0033209=IDA, GO:0007186=IEA, GO:0045121=ISS, GO:0043548=IEA, GO:0020037=IDA, GO:0007260=ISS, GO:0031103=IEA, GO:0008284=IEA, GO:0008285=ISS, GO:0007262=ISS, GO:0005131=ISS, GO:0010811=IDA, GO:0006928=TAS, GO:0031702=IEA, GO:0007204=IEA, GO:0045429=IEA, GO:0035556=TAS, GO:0005737=IDA, GO:0035722=IDA, GO:0043065=ISS, GO:0005143=ISS, GO:0006919=ISS, GO:0061180=ISS, GO:0008631=IEA, GO:0006915=ISS, GO:0008022=IEA, GO:0005524=IEA, GO:0007259=TAS, GO:0007165=ISS, GO:0031904=TAS, GO:0009755=IEA, GO:0006468=TAS, GO:0034612=IDA, GO:0004713=TAS, GO:0051770=ISS, GO:0004715=IEA, GO:0007167=ISS} G-protein coupled receptor signaling pathway, JAK-STAT cascade, JAK-STAT cascade involved in growth hormone signaling pathway, STAT protein import into nucleus, actin filament polymerization, activation of JAK2 kinase activity, activation of MAPKK activity, activation of cysteine-type endopeptidase activity involved in apoptotic process, activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway, apoptotic process, axon regeneration, blood coagulation, cell differentiation, cellular component movement, cytokine-mediated signaling pathway, elevation of cytosolic calcium ion concentration, enzyme linked receptor protein signaling pathway, erythrocyte differentiation, growth hormone receptor signaling pathway, histone H3-Y41 phosphorylation, hormone-mediated signaling pathway, interferon-gamma-mediated signaling pathway, interleukin-12-mediated signaling pathway, intracellular protein kinase cascade, intracellular signal transduction, intrinsic apoptotic signaling pathway in response to oxidative stress, mammary gland epithelium development, mesoderm development, mineralocorticoid receptor signaling pathway, myeloid cell differentiation, negative regulation of DNA binding, negative regulation of cell proliferation, negative regulation of cell-cell adhesion, negative regulation of heart contraction, negative regulation of neuron apoptotic process, peptidyl-tyrosine phosphorylation, platelet-derived growth factor receptor signaling pathway, positive regulation of DNA binding, positive regulation of apoptotic process, positive regulation of cell activation, positive regulation of cell differentiation, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of cell-substrate adhesion, positive regulation of growth hormone receptor signaling pathway, positive regulation of inflammatory response, positive regulation of insulin secretion, positive regulation of interleukin-1 beta production, positive regulation of nitric oxide biosynthetic process, positive regulation of nitric-oxide synthase biosynthetic process, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of phosphoprotein phosphatase activity, positive regulation of protein import into nucleus, translocation, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of tumor necrosis factor production, positive regulation of tyrosine phosphorylation of Stat3 protein, positive regulation of tyrosine phosphorylation of Stat5 protein, protein autophosphorylation, protein phosphorylation, regulation of inflammatory response, regulation of interferon-gamma-mediated signaling pathway, response to antibiotic, response to hydroperoxide, response to interleukin-12, response to lipopolysaccharide, response to tumor necrosis factor, signal transduction, tumor necrosis factor-mediated signaling pathway, tyrosine phosphorylation of STAT protein, tyrosine phosphorylation of Stat1 protein, tyrosine phosphorylation of Stat3 protein, tyrosine phosphorylation of Stat5 protein caveola, cytoplasm, cytoskeleton, cytosol, endomembrane system, endosome lumen, membrane raft, nuclear matrix, nucleus ATP binding, SH2 domain binding, acetylcholine receptor binding, growth hormone receptor binding, heme binding, histone binding, histone kinase activity (H3-Y41 specific), insulin receptor substrate binding, interleukin-12 receptor binding, non-membrane spanning protein tyrosine kinase activity, peptide hormone receptor binding, phosphatidylinositol 3-kinase binding, protein C-terminus binding, protein binding, protein kinase activity, protein kinase binding, protein tyrosine kinase activity, receptor binding, type 1 angiotensin receptor binding Human UniProtKB:Q62120 JAK3 BHF-UCL UniProtKB {GO:0005515=PMID:9045636, GO:0007260=PMID:19290934, GO:0070232=GO_REF:0000024, GO:0032693=GO_REF:0000024, GO:0007262=PMID:19290934, GO:0060397=PMID:19290934, GO:0007243=GO_REF:0000024, GO:0005829=Reactome:REACT_115695, GO:0002731=GO_REF:0000024, GO:0045944=GO_REF:0000019, GO:0030183=GO_REF:0000024, GO:0070670=PMID:7594533, GO:0070672=PMID:7594533, GO:0035771=PMID:7538655, GO:0043029=GO_REF:0000024, GO:0005856=GO_REF:0000002, GO:0043066=GO_REF:0000024, GO:0071104=PMID:7594533, GO:0050868=GO_REF:0000024, GO:0070244=GO_REF:0000024, GO:0042981=GO_REF:0000024, GO:0018108=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0012505=GO_REF:0000039, GO:0016020=GO_REF:0000037, GO:0045221=GO_REF:0000024, GO:0032695=GO_REF:0000024, GO:0045087=GO_REF:0000037, GO:0045626=GO_REF:0000024, GO:0006468=PMID:8022790, GO:0004713=GO_REF:0000024, GO:0004715=GO_REF:0000003, GO:0070669=PMID:9973401, GO:0007167=GO_REF:0000024} P52333 Tyrosine-protein kinase JAK3 protein 20110401 {GO:0005515=IPI, GO:0007260=TAS, GO:0070232=ISS, GO:0032693=ISS, GO:0007262=TAS, GO:0060397=TAS, GO:0007243=ISS, GO:0005829=TAS, GO:0002731=ISS, GO:0045944=IEA, GO:0030183=ISS, GO:0070670=IDA, GO:0070672=TAS, GO:0035771=IDA, GO:0043029=ISS, GO:0005856=IEA, GO:0043066=ISS, GO:0071104=TAS, GO:0050868=ISS, GO:0070244=ISS, GO:0042981=ISS, GO:0018108=ISS, GO:0005524=IEA, GO:0012505=IEA, GO:0016020=IEA, GO:0045221=ISS, GO:0032695=ISS, GO:0045087=IEA, GO:0045626=ISS, GO:0006468=TAS, GO:0004713=ISS, GO:0004715=IEA, GO:0070669=TAS, GO:0007167=ISS} B cell differentiation, JAK-STAT cascade involved in growth hormone signaling pathway, STAT protein import into nucleus, T cell homeostasis, enzyme linked receptor protein signaling pathway, innate immune response, interleukin-4-mediated signaling pathway, intracellular protein kinase cascade, negative regulation of FasL biosynthetic process, negative regulation of T cell activation, negative regulation of T-helper 1 cell differentiation, negative regulation of apoptotic process, negative regulation of dendritic cell cytokine production, negative regulation of interleukin-10 production, negative regulation of interleukin-12 production, negative regulation of thymocyte apoptotic process, peptidyl-tyrosine phosphorylation, positive regulation of transcription from RNA polymerase II promoter, protein phosphorylation, regulation of T cell apoptotic process, regulation of apoptotic process, response to interleukin-15, response to interleukin-2, response to interleukin-4, response to interleukin-9, tyrosine phosphorylation of STAT protein cytoskeleton, cytosol, endomembrane system, membrane ATP binding, non-membrane spanning protein tyrosine kinase activity, protein binding, protein tyrosine kinase activity Human UniProtKB:Q62137 JAKMIP1 MGI UniProtKB {GO:0008017=GO_REF:0000002, GO:0005737=GO_REF:0000037, GO:0030529=PMID:14718537, GO:0003723=PMID:14718537, GO:0005874=GO_REF:0000019, GO:0050811=PMID:14718537, GO:0019894=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0019900=GO_REF:0000002, GO:0019898=PMID:14718537} Q96N16 Janus kinase and microtubule-interacting protein 1 protein 20040730 {GO:0008017=IEA, GO:0005737=IEA, GO:0030529=IDA, GO:0003723=IDA, GO:0005874=IEA, GO:0050811=IDA, GO:0019894=IEA, GO:0015031=IEA, GO:0019900=IEA, GO:0019898=IDA} protein transport cytoplasm, extrinsic to membrane, microtubule, ribonucleoprotein complex GABA receptor binding, RNA binding, kinase binding, kinesin binding, microtubule binding Human JAKMIP2 UniProtKB UniProtKB {GO:0008017=GO_REF:0000002, GO:0005794=GO_REF:0000039, GO:0016301=GO_REF:0000038, GO:0019900=GO_REF:0000002} Q96AA8 Janus kinase and microtubule-interacting protein 2 protein 20130413 {GO:0008017=IEA, GO:0005794=IEA, GO:0016301=IEA, GO:0019900=IEA} Golgi apparatus kinase activity, kinase binding, microtubule binding Human UniProtKB-SubCell:SL-0132 JAM2 IntAct UniProtKB {GO:0005515=PMID:21982860, GO:0016337=PMID:10779521, GO:0007162=GO_REF:0000019, GO:0005886=Reactome:REACT_12053, GO:0046982=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:10779521, GO:0005923=GO_REF:0000039, GO:0050900=Reactome:REACT_12051} P57087 Junctional adhesion molecule B protein 20130415 {GO:0005515=IPI, GO:0016337=NAS, GO:0007162=IEA, GO:0005886=TAS, GO:0046982=IEA, GO:0007596=TAS, GO:0005887=NAS, GO:0005923=IEA, GO:0050900=TAS} blood coagulation, cell-cell adhesion, leukocyte migration, negative regulation of cell adhesion integral to plasma membrane, plasma membrane, tight junction protein binding, protein heterodimerization activity Human UniProtKB:Q9BX67 JAM3 IntAct UniProtKB {GO:0030057=PMID:15194813, GO:0005515=PMID:21982860, GO:0001780=GO_REF:0000019, GO:0005886=Reactome:REACT_12053, GO:0007286=GO_REF:0000019, GO:0030010=GO_REF:0000019, GO:0050900=Reactome:REACT_12051, GO:0005615=PMID:20592283, GO:0042803=GO_REF:0000019, GO:0033010=GO_REF:0000019, GO:0043220=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0002523=GO_REF:0000019, GO:0042552=GO_REF:0000019, GO:0090138=GO_REF:0000019, GO:0044291=PMID:15994945, GO:0001525=PMID:20592283, GO:0002250=GO_REF:0000019, GO:0005178=PMID:15194813, GO:0007160=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0090022=PMID:15194813, GO:0016021=GO_REF:0000037, GO:0005923=GO_REF:0000019, GO:0002318=GO_REF:0000019} Q9BX67 Junctional adhesion molecule C protein 20130415 {GO:0030057=IDA, GO:0005515=IPI, GO:0001780=IEA, GO:0005886=TAS, GO:0007286=IEA, GO:0030010=IEA, GO:0050900=TAS, GO:0005615=IDA, GO:0042803=IEA, GO:0033010=IEA, GO:0043220=IEA, GO:0046982=IEA, GO:0002523=IEA, GO:0042552=IEA, GO:0090138=IEA, GO:0044291=IDA, GO:0001525=IDA, GO:0002250=IEA, GO:0005178=IPI, GO:0007160=IEA, GO:0007596=TAS, GO:0090022=IDA, GO:0016021=IEA, GO:0005923=IEA, GO:0002318=IEA} adaptive immune response, angiogenesis, blood coagulation, cell-matrix adhesion, establishment of cell polarity, leukocyte migration, leukocyte migration involved in inflammatory response, myelination, myeloid progenitor cell differentiation, neutrophil homeostasis, regulation of actin cytoskeleton organization by cell-cell adhesion, regulation of neutrophil chemotaxis, spermatid development Schmidt-Lanterman incisure, cell-cell contact zone, desmosome, extracellular space, integral to membrane, paranodal junction, plasma membrane, tight junction integrin binding, protein binding, protein heterodimerization activity, protein homodimerization activity Human UniProtKB:P57087 JARID2 PINC UniProtKB {GO:0008285=GO_REF:0000019, GO:0032452=GO_REF:0000024, GO:0005634=PMID:20075857, GO:0048538=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0007417=PMID:8894700, GO:0048536=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0001889=GO_REF:0000019, GO:0048863=GO_REF:0000024, GO:0031061=GO_REF:0000024, GO:0051574=GO_REF:0000024, GO:0035097=GO_REF:0000024, GO:0035098=PMID:20075857, GO:0003682=GO_REF:0000024, GO:0045892=GO_REF:0000024} Q92833 Protein Jumonji protein 20030904 {GO:0008285=IEA, GO:0032452=ISS, GO:0005634=IDA, GO:0048538=IEA, GO:0000122=IEA, GO:0007417=TAS, GO:0048536=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0001889=IEA, GO:0048863=ISS, GO:0031061=ISS, GO:0051574=ISS, GO:0035097=ISS, GO:0035098=IDA, GO:0003682=ISS, GO:0045892=ISS} central nervous system development, liver development, negative regulation of cell proliferation, negative regulation of histone methylation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of histone H3-K9 methylation, spleen development, stem cell differentiation, thymus development, transcription, DNA-dependent ESC/E(Z) complex, histone methyltransferase complex, nucleus DNA binding, chromatin binding, histone demethylase activity Human JAZF1 MGI UniProtKB {GO:0017053=PMID:15302918, GO:0003714=PMID:15302918, GO:0008270=GO_REF:0000002, GO:0000122=PMID:15302918, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q86VZ6 Juxtaposed with another zinc finger protein 1 protein 20041221 {GO:0017053=IDA, GO:0003714=IDA, GO:0008270=IEA, GO:0000122=IDA, GO:0003676=IEA, GO:0006351=IEA} negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent transcriptional repressor complex nucleic acid binding, transcription corepressor activity, zinc ion binding Human JDP2 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0003690=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0031065=GO_REF:0000019, GO:0045599=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0000122=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q8WYK2 Jun dimerization protein 2 protein 20130413 {GO:0043565=IEA, GO:0003700=IEA, GO:0003690=IEA, GO:0046982=IEA, GO:0031065=IEA, GO:0045599=IEA, GO:0003682=IEA, GO:0005634=IEA, GO:0000122=IEA, GO:0006351=IEA} negative regulation of fat cell differentiation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of histone deacetylation, transcription, DNA-dependent nucleus chromatin binding, double-stranded DNA binding, protein heterodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0191 JKAMP UniProtKB UniProtKB {GO:0006986=GO_REF:0000037, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0030433=PMID:19269966, GO:0031625=PMID:19269966} Q9P055 JNK1/MAPK8-associated membrane protein protein 20100625 {GO:0006986=IEA, GO:0005789=IEA, GO:0016021=IEA, GO:0030433=IDA, GO:0031625=IPI} ER-associated protein catabolic process, response to unfolded protein endoplasmic reticulum membrane, integral to membrane ubiquitin protein ligase binding Human JMJD1C IntAct UniProtKB {GO:0005515=PMID:17353003, GO:0005622=PMID:7776974, GO:0046966=PMID:7776974, GO:0006355=PMID:7776974, GO:0007596=Reactome:REACT_604, GO:0005654=Reactome:REACT_25371, GO:0016702=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q15652 Probable JmjC domain-containing histone demethylation protein 2C protein 20130415 {GO:0005515=IPI, GO:0005622=NAS, GO:0046966=TAS, GO:0006355=TAS, GO:0007596=TAS, GO:0005654=TAS, GO:0016702=IEA, GO:0046872=IEA, GO:0006351=IEA, GO:0016568=IEA} blood coagulation, chromatin modification, regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleoplasm metal ion binding, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, protein binding, thyroid hormone receptor binding Human UniProtKB:P10275 JMJD4 null null {} null null null null {} null null null JMJD6 BHF-UCL UniProtKB {GO:0008380=GO_REF:0000037, GO:0005515=PMID:19574390, GO:0003727=PMID:20679243, GO:0048024=PMID:19574390, GO:0070815=PMID:19574390, GO:0005886=GO_REF:0000019, GO:0060041=GO_REF:0000019, GO:0030324=GO_REF:0000019, GO:0003723=PMID:21060799, GO:0002040=GO_REF:0000024, GO:0005634=PMID:17534701, GO:0042802=PMID:17534701, GO:0007507=GO_REF:0000019, GO:0033746=PMID:17947579, GO:0048821=GO_REF:0000019, GO:0033749=PMID:17947579, GO:0004872=GO_REF:0000019, GO:0006397=GO_REF:0000037, GO:0033077=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0070079=PMID:17947579, GO:0005506=PMID:20679243, GO:0070078=PMID:17947579, GO:0001822=GO_REF:0000019, GO:0005730=PMID:21060799, GO:0006915=GO_REF:0000019, GO:0043654=GO_REF:0000019, GO:0018395=PMID:19574390, GO:0006351=GO_REF:0000037, GO:0042116=GO_REF:0000019, GO:0005654=PMID:21060799, GO:0016702=GO_REF:0000037, GO:0007166=GO_REF:0000019} Q6NYC1 Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 protein 20081104 {GO:0008380=IEA, GO:0005515=IPI, GO:0003727=IDA, GO:0048024=IMP, GO:0070815=IDA, GO:0005886=IEA, GO:0060041=IEA, GO:0030324=IEA, GO:0003723=TAS, GO:0002040=ISS, GO:0005634=IDA, GO:0042802=IDA, GO:0007507=IEA, GO:0033746=IDA, GO:0048821=IEA, GO:0033749=IDA, GO:0004872=IEA, GO:0006397=IEA, GO:0033077=IEA, GO:0006355=IEA, GO:0070079=IDA, GO:0005506=IDA, GO:0070078=IDA, GO:0001822=IEA, GO:0005730=IDA, GO:0006915=IEA, GO:0043654=IEA, GO:0018395=IDA, GO:0006351=IEA, GO:0042116=IEA, GO:0005654=IDA, GO:0016702=IEA, GO:0007166=IEA} RNA splicing, T cell differentiation in thymus, apoptotic process, cell surface receptor signaling pathway, erythrocyte development, heart development, histone H3-R2 demethylation, histone H4-R3 demethylation, kidney development, lung development, mRNA processing, macrophage activation, peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine, recognition of apoptotic cell, regulation of mRNA splicing, via spliceosome, regulation of transcription, DNA-dependent, retina development in camera-type eye, sprouting angiogenesis, transcription, DNA-dependent nucleolus, nucleoplasm, nucleus, plasma membrane RNA binding, histone demethylase activity (H3-R2 specific), histone demethylase activity (H4-R3 specific), identical protein binding, iron ion binding, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, peptidyl-lysine 5-dioxygenase activity, protein binding, receptor activity, single-stranded RNA binding Human JMY IntAct UniProtKB {GO:0005515=PMID:17170761, GO:0034314=GO_REF:0000024, GO:0070060=GO_REF:0000024, GO:0043065=GO_REF:0000024, GO:0006357=GO_REF:0000024, GO:0003713=GO_REF:0000024, GO:0003779=GO_REF:0000037, GO:0005634=GO_REF:0000024, GO:0006917=GO_REF:0000024, GO:0070358=GO_REF:0000024, GO:0005737=GO_REF:0000037, GO:0051091=GO_REF:0000024, GO:0006281=GO_REF:0000037, GO:0007050=GO_REF:0000024, GO:0005856=GO_REF:0000039, GO:0031252=PMID:19287377} Q8N9B5 Junction-mediating and -regulatory protein protein 20130415 {GO:0005515=IPI, GO:0034314=ISS, GO:0070060=ISS, GO:0043065=ISS, GO:0006357=ISS, GO:0003713=ISS, GO:0003779=IEA, GO:0005634=ISS, GO:0006917=ISS, GO:0070358=ISS, GO:0005737=IEA, GO:0051091=ISS, GO:0006281=IEA, GO:0007050=ISS, GO:0005856=IEA, GO:0031252=IDA} 'de novo' actin filament nucleation, Arp2/3 complex-mediated actin nucleation, DNA repair, actin polymerization-dependent cell motility, cell cycle arrest, induction of apoptosis, positive regulation of apoptotic process, positive regulation of sequence-specific DNA binding transcription factor activity, regulation of transcription from RNA polymerase II promoter cell leading edge, cytoplasm, cytoskeleton, nucleus actin binding, protein binding, transcription coactivator activity Human UniProtKB:Q00987 JOSD1 UniProtKB UniProtKB {GO:0006508=GO_REF:0000037, GO:0008242=GO_REF:0000002} Q15040 Josephin-1 protein 20130413 {GO:0006508=IEA, GO:0008242=IEA} proteolysis omega peptidase activity Human UniProtKB-KW:KW-0645 JOSD2 UniProtKB UniProtKB {GO:0016579=PMID:21118805, GO:0004843=PMID:21118805, GO:0006508=GO_REF:0000037, GO:0008242=GO_REF:0000002} Q8TAC2 Josephin-2 protein 20110218 {GO:0016579=IDA, GO:0004843=IDA, GO:0006508=IEA, GO:0008242=IEA} protein deubiquitination, proteolysis omega peptidase activity, ubiquitin-specific protease activity Human JPH1 BHF-UCL UniProtKB {GO:0014701=PMID:19095005, GO:0003674=GO_REF:0000015, GO:0030018=GO_REF:0000019, GO:0060402=PMID:19095005, GO:0007517=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0060314=PMID:19095005, GO:0030314=PMID:10891348, GO:0016021=GO_REF:0000037, GO:0008307=GO_REF:0000019} Q9HDC5 Junctophilin-1 protein 20090203 {GO:0014701=TAS, GO:0003674=ND, GO:0030018=IEA, GO:0060402=TAS, GO:0007517=IEA, GO:0005886=IEA, GO:0060314=TAS, GO:0030314=NAS, GO:0016021=IEA, GO:0008307=IEA} calcium ion transport into cytosol, muscle organ development, regulation of ryanodine-sensitive calcium-release channel activity Z disc, integral to membrane, junctional membrane complex, junctional sarcoplasmic reticulum membrane, plasma membrane molecular_function, structural constituent of muscle Human JPH2 BHF-UCL UniProtKB {GO:0060316=PMID:20095964, GO:0005515=PMID:20095964, GO:0014701=PMID:19095005, GO:0030018=GO_REF:0000019, GO:0060402=PMID:19095005, GO:0005886=GO_REF:0000039, GO:0060314=PMID:19095005, GO:0030314=GO_REF:0000019, GO:0015278=PMID:20095964, GO:0016021=GO_REF:0000037, GO:0055024=GO_REF:0000019, GO:0055074=PMID:20095964} Q9BR39 Junctophilin-2 protein 20090203 {GO:0060316=IDA, GO:0005515=IPI, GO:0014701=TAS, GO:0030018=IEA, GO:0060402=TAS, GO:0005886=IEA, GO:0060314=TAS, GO:0030314=IEA, GO:0015278=IDA, GO:0016021=IEA, GO:0055024=IEA, GO:0055074=IDA} calcium ion homeostasis, calcium ion transport into cytosol, positive regulation of ryanodine-sensitive calcium-release channel activity, regulation of cardiac muscle tissue development, regulation of ryanodine-sensitive calcium-release channel activity Z disc, integral to membrane, junctional membrane complex, junctional sarcoplasmic reticulum membrane, plasma membrane calcium-release channel activity, protein binding Human JPH3 BHF-UCL UniProtKB {GO:0040011=GO_REF:0000019, GO:0014701=PMID:19095005, GO:0003674=GO_REF:0000015, GO:0060402=PMID:19095005, GO:0005886=GO_REF:0000039, GO:0048168=GO_REF:0000019, GO:0060314=PMID:19095005, GO:0030314=GO_REF:0000019, GO:0015278=GO_REF:0000019, GO:0007613=GO_REF:0000019, GO:0016021=PMID:10891348, GO:0035640=GO_REF:0000019} Q8WXH2 Junctophilin-3 protein 20090203 {GO:0040011=IEA, GO:0014701=TAS, GO:0003674=ND, GO:0060402=TAS, GO:0005886=IEA, GO:0048168=IEA, GO:0060314=TAS, GO:0030314=IEA, GO:0015278=IEA, GO:0007613=IEA, GO:0016021=NAS, GO:0035640=IEA} calcium ion transport into cytosol, exploration behavior, locomotion, memory, regulation of neuronal synaptic plasticity, regulation of ryanodine-sensitive calcium-release channel activity integral to membrane, junctional membrane complex, junctional sarcoplasmic reticulum membrane, plasma membrane calcium-release channel activity, molecular_function Human JRK UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005634=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0003677=GO_REF:0000037} O75564 Jerky protein homolog protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0005634=IEA, GO:0005575=ND, GO:0003677=IEA} biological_process cellular_component, nucleus DNA binding, molecular_function Human JSRP1 UniProtKB UniProtKB {GO:0003009=PMID:22927026, GO:0033017=GO_REF:0000039} Q96MG2 Junctional sarcoplasmic reticulum protein 1 protein 20121129 {GO:0003009=IDA, GO:0033017=IEA} skeletal muscle contraction sarcoplasmic reticulum membrane Human JTB PINC UniProtKB {GO:0043066=GO_REF:0000019, GO:0005813=PMID:21225229, GO:0019901=PMID:21225229, GO:0005819=PMID:21225229, GO:0006915=GO_REF:0000037, GO:0030496=PMID:21225229, GO:0005739=GO_REF:0000039, GO:0005737=PMID:21225229, GO:0007067=PMID:21225229, GO:0016020=PMID:10321732, GO:0005887=PMID:10321732, GO:0042127=GO_REF:0000019, GO:0045860=PMID:21225229} O76095 Protein JTB protein 20030904 {GO:0043066=IEA, GO:0005813=IDA, GO:0019901=IDA, GO:0005819=IDA, GO:0006915=IEA, GO:0030496=IDA, GO:0005739=IEA, GO:0005737=IDA, GO:0007067=IMP, GO:0016020=TAS, GO:0005887=TAS, GO:0042127=IEA, GO:0045860=IMP} apoptotic process, mitosis, negative regulation of apoptotic process, positive regulation of protein kinase activity, regulation of cell proliferation centrosome, cytoplasm, integral to plasma membrane, membrane, midbody, mitochondrion, spindle protein kinase binding Human JUN GOC UniProtKB {GO:0005515=PMID:21988832, GO:0042542=GO_REF:0000019, GO:0001190=PMID:19861239, GO:0003700=PMID:9732876, GO:0044212=PMID:9732876, GO:0003705=PMID:19861239, GO:0051403=Reactome:REACT_21308, GO:0051591=GO_REF:0000019, GO:0002756=Reactome:REACT_6809, GO:0043524=GO_REF:0000019, GO:0003690=GO_REF:0000019, GO:0043525=GO_REF:0000019, GO:0045657=GO_REF:0000019, GO:0002755=Reactome:REACT_27215, GO:0017053=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0007179=PMID:9732876, GO:0007612=GO_REF:0000019, GO:0001102=PMID:19861239, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0005719=PMID:19861239, GO:0034134=Reactome:REACT_7980, GO:0007568=GO_REF:0000019, GO:0045740=GO_REF:0000019, GO:0003713=PMID:2833704, GO:0002224=Reactome:REACT_9020, GO:0043923=PMID:2833704, GO:0043392=PMID:14645924, GO:0043922=PMID:2833704, GO:0001889=GO_REF:0000019, GO:0032321=PMID:11804590, GO:0007184=PMID:9732876, GO:0045087=Reactome:REACT_6802, GO:0007623=GO_REF:0000019, GO:0071837=GO_REF:0000019, GO:0000980=PMID:19861239, GO:0035666=Reactome:REACT_25281, GO:0034166=Reactome:REACT_9027, GO:0005654=Reactome:REACT_21404, GO:0045893=PMID:9732876, GO:0045892=PMID:2833704, GO:0034162=Reactome:REACT_9047, GO:0008134=PMID:16007074, GO:0035026=GO_REF:0000019, GO:0031103=GO_REF:0000019, GO:0034142=Reactome:REACT_6894, GO:0008285=GO_REF:0000019, GO:0051899=GO_REF:0000019, GO:0035497=PMID:19861239, GO:0001836=GO_REF:0000019, GO:0048146=GO_REF:0000019, GO:0060395=PMID:9732876, GO:0005829=GO_REF:0000019, GO:0031953=GO_REF:0000019, GO:0051090=Reactome:REACT_21326, GO:0045944=PMID:19861239, GO:0051726=GO_REF:0000019, GO:0071277=GO_REF:0000019, GO:0030224=GO_REF:0000019, GO:0034097=GO_REF:0000019, GO:0034138=Reactome:REACT_6783, GO:0001774=GO_REF:0000019, GO:0009314=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0070412=PMID:9732876, GO:0001525=GO_REF:0000019, GO:0051365=GO_REF:0000019, GO:0000228=PMID:10918580, GO:0003677=PMID:2825349, GO:0048661=GO_REF:0000019, GO:0003151=GO_REF:0000019, GO:0005100=PMID:11804590, GO:0009612=GO_REF:0000019, GO:0001077=GO_REF:0000019, GO:0001938=GO_REF:0000019, GO:0034146=Reactome:REACT_9061} P05412 Transcription factor AP-1 protein 20130413 {GO:0005515=IPI, GO:0042542=IEA, GO:0001190=IC, GO:0003700=IDA, GO:0044212=IDA, GO:0003705=IC, GO:0051403=TAS, GO:0051591=IEA, GO:0002756=TAS, GO:0043524=IEA, GO:0003690=IEA, GO:0043525=IEA, GO:0045657=IEA, GO:0002755=TAS, GO:0017053=IEA, GO:0032496=IEA, GO:0007179=IDA, GO:0007612=IEA, GO:0001102=IPI, GO:0038124=TAS, GO:0038123=TAS, GO:0005719=IDA, GO:0034134=TAS, GO:0007568=IEA, GO:0045740=IEA, GO:0003713=IDA, GO:0002224=TAS, GO:0043923=IDA, GO:0043392=IDA, GO:0043922=IDA, GO:0001889=IEA, GO:0032321=IDA, GO:0007184=IDA, GO:0045087=TAS, GO:0007623=IEA, GO:0071837=IEA, GO:0000980=IDA, GO:0035666=TAS, GO:0034166=TAS, GO:0005654=TAS, GO:0045893=IDA, GO:0045892=IDA, GO:0034162=TAS, GO:0008134=IPI, GO:0035026=IEA, GO:0031103=IEA, GO:0034142=TAS, GO:0008285=IEA, GO:0051899=IEA, GO:0035497=IDA, GO:0001836=IEA, GO:0048146=IEA, GO:0060395=IDA, GO:0005829=IEA, GO:0031953=IEA, GO:0051090=TAS, GO:0045944=IC, GO:0051726=IEA, GO:0071277=IEA, GO:0030224=IEA, GO:0034097=IEA, GO:0034138=TAS, GO:0001774=IEA, GO:0009314=IEA, GO:0005667=IEA, GO:0042493=IEA, GO:0070412=IPI, GO:0001525=IEA, GO:0051365=IEA, GO:0000228=TAS, GO:0003677=TAS, GO:0048661=IEA, GO:0003151=IEA, GO:0005100=IDA, GO:0009612=IEA, GO:0001077=IEA, GO:0001938=IEA, GO:0034146=TAS} MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, SMAD protein import into nucleus, SMAD protein signal transduction, TRIF-dependent toll-like receptor signaling pathway, aging, angiogenesis, axon regeneration, cellular response to calcium ion, cellular response to potassium ion starvation, circadian rhythm, innate immune response, leading edge cell differentiation, learning, liver development, membrane depolarization, microglial cell activation, monocyte differentiation, negative regulation by host of viral transcription, negative regulation of DNA binding, negative regulation of cell proliferation, negative regulation of neuron apoptotic process, negative regulation of protein autophosphorylation, negative regulation of transcription, DNA-dependent, outflow tract morphogenesis, positive regulation by host of viral transcription, positive regulation of DNA replication, positive regulation of Rho GTPase activity, positive regulation of endothelial cell proliferation, positive regulation of fibroblast proliferation, positive regulation of monocyte differentiation, positive regulation of neuron apoptotic process, positive regulation of smooth muscle cell proliferation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of cell cycle, regulation of sequence-specific DNA binding transcription factor activity, release of cytochrome c from mitochondria, response to cAMP, response to cytokine stimulus, response to drug, response to hydrogen peroxide, response to lipopolysaccharide, response to mechanical stimulus, response to radiation, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, transforming growth factor beta receptor signaling pathway cytosol, nuclear chromosome, nuclear euchromatin, nucleoplasm, transcription factor complex, transcriptional repressor complex DNA binding, HMG box domain binding, R-SMAD binding, RNA polymerase II activating transcription factor binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II distal enhancer sequence-specific DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription, Rho GTPase activator activity, cAMP response element binding, double-stranded DNA binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, transcription factor binding, transcription regulatory region DNA binding Human JUNB HPA UniProtKB {GO:0005515=PMID:21988832, GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_12627, GO:0003700=GO_REF:0000019, GO:0033687=GO_REF:0000019, GO:0045597=GO_REF:0000019, GO:0043434=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0051591=GO_REF:0000019, GO:0032870=GO_REF:0000019, GO:0046697=GO_REF:0000019, GO:0003690=GO_REF:0000019, GO:0045944=Reactome:REACT_120734, GO:0051726=GO_REF:0000019, GO:0060716=GO_REF:0000019, GO:0071277=GO_REF:0000019, GO:0007179=Reactome:REACT_6844, GO:0009416=GO_REF:0000019, GO:0034097=GO_REF:0000019, GO:0000785=PMID:2513129, GO:0051412=GO_REF:0000019, GO:0000977=GO_REF:0000019, GO:0006357=PMID:2513129, GO:0003714=PMID:2513129, GO:0042493=GO_REF:0000019, GO:0003713=PMID:2513129, GO:0005730=GO_REF:0000052, GO:0030316=GO_REF:0000019, GO:0060136=GO_REF:0000019, GO:0001829=GO_REF:0000019, GO:0003677=PMID:10764760, GO:0006351=Reactome:REACT_121061, GO:0001649=GO_REF:0000019, GO:0009612=GO_REF:0000019, GO:0032570=GO_REF:0000019, GO:0005654=Reactome:REACT_121406, GO:0001570=GO_REF:0000019} P17275 Transcription factor jun-B protein 20081203 {GO:0005515=IPI, GO:0010467=TAS, GO:0006367=TAS, GO:0003700=IEA, GO:0033687=IEA, GO:0045597=IEA, GO:0043434=IEA, GO:0005634=IDA, GO:0051591=IEA, GO:0032870=IEA, GO:0046697=IEA, GO:0003690=IEA, GO:0045944=TAS, GO:0051726=IEA, GO:0060716=IEA, GO:0071277=IEA, GO:0007179=TAS, GO:0009416=IEA, GO:0034097=IEA, GO:0000785=TAS, GO:0051412=IEA, GO:0000977=IEA, GO:0006357=TAS, GO:0003714=TAS, GO:0042493=IEA, GO:0003713=TAS, GO:0005730=IDA, GO:0030316=IEA, GO:0060136=IEA, GO:0001829=IEA, GO:0003677=TAS, GO:0006351=TAS, GO:0001649=IEA, GO:0009612=IEA, GO:0032570=IEA, GO:0005654=TAS, GO:0001570=IEA} cellular response to calcium ion, cellular response to hormone stimulus, decidualization, embryonic process involved in female pregnancy, gene expression, labyrinthine layer blood vessel development, osteoblast differentiation, osteoblast proliferation, osteoclast differentiation, positive regulation of cell differentiation, positive regulation of transcription from RNA polymerase II promoter, regulation of cell cycle, regulation of transcription from RNA polymerase II promoter, response to cAMP, response to corticosterone stimulus, response to cytokine stimulus, response to drug, response to light stimulus, response to mechanical stimulus, response to peptide hormone stimulus, response to progesterone stimulus, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, trophectodermal cell differentiation, vasculogenesis chromatin, nucleolus, nucleoplasm, nucleus DNA binding, RNA polymerase II regulatory region sequence-specific DNA binding, double-stranded DNA binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, transcription corepressor activity NOT Human JUND IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0014070=GO_REF:0000019, GO:0016922=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0006357=PMID:1903194, GO:0044212=PMID:1903194, GO:0006366=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0043434=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0009612=GO_REF:0000019, GO:0045669=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0003690=GO_REF:0000019, GO:0002076=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0071277=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0007623=GO_REF:0000019, GO:0009416=GO_REF:0000019, GO:0000785=PMID:1903194} P17535 Transcription factor jun-D protein 20130415 {GO:0005515=IPI, GO:0014070=IEA, GO:0016922=IEA, GO:0003700=IEA, GO:0006357=TAS, GO:0044212=IDA, GO:0006366=IEA, GO:0007568=IEA, GO:0043434=IEA, GO:0005634=IEA, GO:0009612=IEA, GO:0045669=IEA, GO:0043565=IEA, GO:0043234=IEA, GO:0003690=IEA, GO:0002076=IEA, GO:0045944=IEA, GO:0071277=IEA, GO:0032496=IEA, GO:0007623=IEA, GO:0009416=IEA, GO:0000785=TAS} aging, cellular response to calcium ion, circadian rhythm, osteoblast development, positive regulation of osteoblast differentiation, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, response to light stimulus, response to lipopolysaccharide, response to mechanical stimulus, response to organic cyclic compound, response to peptide hormone stimulus, transcription from RNA polymerase II promoter chromatin, nucleus, protein complex double-stranded DNA binding, ligand-dependent nuclear receptor binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding Human UniProtKB:Q00987 JUP BHF-UCL UniProtKB {GO:0030057=PMID:1639850, GO:0005515=PMID:16917092, GO:0030056=GO_REF:0000024, GO:0030018=GO_REF:0000033, GO:0003181=GO_REF:0000033, GO:0090263=PMID:14661054, GO:0016342=PMID:7650039, GO:0048599=GO_REF:0000033, GO:0042803=GO_REF:0000024, GO:0003308=GO_REF:0000033, GO:0086069=PMID:17924338, GO:0016337=PMID:18937352, GO:0050982=PMID:18937352, GO:0032993=PMID:14661054, GO:0042127=PMID:17924338, GO:0002159=PMID:22889254, GO:0005856=GO_REF:0000024, GO:0086005=PMID:17924338, GO:0071665=PMID:14661054, GO:0045296=PMID:1639850, GO:0019901=GO_REF:0000033, GO:0045294=PMID:7890674, GO:0019903=PMID:8663237, GO:0034329=Reactome:REACT_20676, GO:0003713=PMID:14661054, GO:0000122=GO_REF:0000033, GO:0045216=Reactome:REACT_19331, GO:0003136=GO_REF:0000033, GO:0009898=GO_REF:0000024, GO:0042307=PMID:10825188, GO:0043588=GO_REF:0000033, GO:0034332=Reactome:REACT_19195, GO:0005882=GO_REF:0000019, GO:0007369=GO_REF:0000033, GO:0005886=PMID:14661054, GO:0005634=PMID:14661054, GO:0086091=PMID:17924338, GO:0015629=GO_REF:0000033, GO:0051291=GO_REF:0000019, GO:0005829=GO_REF:0000024, GO:0005916=GO_REF:0000033, GO:0005915=GO_REF:0000024, GO:0016323=GO_REF:0000033, GO:0071681=PMID:10868478, GO:0051091=PMID:14661054, GO:0005737=PMID:14661054, GO:0005913=PMID:10403777, GO:0005911=PMID:14661054, GO:0007016=PMID:22889254, GO:0005667=GO_REF:0000033, GO:0071603=GO_REF:0000024, GO:0042981=PMID:17924338, GO:0007398=GO_REF:0000033, GO:0016328=GO_REF:0000019, GO:0016327=GO_REF:0000019, GO:0007399=GO_REF:0000033, GO:0000902=GO_REF:0000033, GO:0016477=PMID:18937352, GO:0016331=GO_REF:0000033, GO:0005198=PMID:22889254, GO:0005199=PMID:7650039} P14923 Junction plakoglobin protein 20120625 {GO:0030057=IDA, GO:0005515=IPI, GO:0030056=ISS, GO:0030018=IBA, GO:0003181=IBA, GO:0090263=IC, GO:0016342=IDA, GO:0048599=IBA, GO:0042803=ISS, GO:0003308=IBA, GO:0086069=IMP, GO:0016337=IDA, GO:0050982=IDA, GO:0032993=IDA, GO:0042127=IDA, GO:0002159=IDA, GO:0005856=ISS, GO:0086005=IMP, GO:0071665=IDA, GO:0045296=IPI, GO:0019901=IBA, GO:0045294=IPI, GO:0019903=IPI, GO:0034329=TAS, GO:0003713=IDA, GO:0000122=IKR, GO:0045216=TAS, GO:0003136=IBA, GO:0009898=ISS, GO:0042307=IDA, GO:0043588=IBA, GO:0034332=TAS, GO:0005882=IEA, GO:0007369=IBA, GO:0005886=IDA, GO:0005634=IMP, GO:0086091=IMP, GO:0015629=IBA, GO:0051291=IEA, GO:0005829=ISS, GO:0005916=IBA, GO:0005915=ISS, GO:0016323=IBA, GO:0071681=IDA, GO:0051091=IDA, GO:0005737=IMP, GO:0005913=IDA, GO:0005911=IDA, GO:0007016=NAS, GO:0005667=IKR, GO:0071603=ISS, GO:0042981=IDA, GO:0007398=IBA, GO:0016328=IEA, GO:0016327=IEA, GO:0007399=IBA, GO:0000902=IBA, GO:0016477=IMP, GO:0016331=IBA, GO:0005198=NAS, GO:0005199=IC} adherens junction organization, atrioventricular valve morphogenesis, bundle of His cell to Purkinje myocyte communication, cell junction assembly, cell migration, cell morphogenesis, cell-cell adhesion, cell-cell junction organization, cellular response to indole-3-methanol, cytoskeletal anchoring at plasma membrane, desmosome assembly, detection of mechanical stimulus, ectoderm development, endothelial cell-cell adhesion, gastrulation, morphogenesis of embryonic epithelium, negative regulation of Wnt receptor signaling pathway involved in heart development, negative regulation of heart induction by canonical Wnt receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, nervous system development, oocyte development, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of protein import into nucleus, positive regulation of sequence-specific DNA binding transcription factor activity, protein heterooligomerization, regulation of apoptotic process, regulation of cell proliferation, regulation of heart rate by cardiac conduction, regulation of ventricular cardiac muscle cell action potential, skin development Z disc, actin cytoskeleton, apicolateral plasma membrane, basolateral plasma membrane, catenin complex, cell-cell adherens junction, cell-cell junction, cytoplasm, cytoskeleton, cytosol, desmosome, fascia adherens, gamma-catenin-TCF7L2 complex, hemidesmosome, intermediate filament, internal side of plasma membrane, lateral plasma membrane, nucleus, plasma membrane, protein-DNA complex, transcription factor complex, zonula adherens alpha-catenin binding, cadherin binding, protein binding, protein homodimerization activity, protein kinase binding, protein phosphatase binding, structural constituent of cell wall, structural molecule activity, transcription coactivator activity Human UniProtKB:P15924 KAL1 PINC UniProtKB {GO:0006935=PMID:8842728, GO:0005886=GO_REF:0000039, GO:0007411=PMID:1922361, GO:0004867=GO_REF:0000037, GO:0005578=PMID:8832397, GO:0006928=PMID:1922361, GO:0007155=GO_REF:0000037, GO:0005615=PMID:8842728, GO:0008201=GO_REF:0000037, GO:0005201=PMID:8842728} P23352 Anosmin-1 protein 20030904 {GO:0006935=TAS, GO:0005886=IEA, GO:0007411=TAS, GO:0004867=IEA, GO:0005578=TAS, GO:0006928=TAS, GO:0007155=IEA, GO:0005615=TAS, GO:0008201=IEA, GO:0005201=TAS} axon guidance, cell adhesion, cellular component movement, chemotaxis extracellular space, plasma membrane, proteinaceous extracellular matrix extracellular matrix structural constituent, heparin binding, serine-type endopeptidase inhibitor activity Human KALRN Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0007264=Reactome:REACT_11044, GO:0035023=GO_REF:0000002, GO:0006915=Reactome:REACT_13638, GO:0015629=PMID:10023074, GO:0097190=Reactome:REACT_13720, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_19301, GO:0007399=GO_REF:0000024, GO:0005085=PMID:9285789, GO:0035556=GO_REF:0000024, GO:0005622=GO_REF:0000002, GO:0007165=PMID:9285789, GO:0005543=GO_REF:0000002, GO:0004674=GO_REF:0000037, GO:0006468=PMID:10023074, GO:0005089=GO_REF:0000002, GO:0016192=PMID:9285789} O60229 Kalirin protein 20130301 {GO:0051056=TAS, GO:0048011=TAS, GO:0007264=TAS, GO:0035023=IEA, GO:0006915=TAS, GO:0015629=TAS, GO:0097190=TAS, GO:0005524=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0007399=ISS, GO:0005085=TAS, GO:0035556=ISS, GO:0005622=IEA, GO:0007165=TAS, GO:0005543=IEA, GO:0004674=IEA, GO:0006468=TAS, GO:0005089=IEA, GO:0016192=TAS} apoptotic process, apoptotic signaling pathway, intracellular signal transduction, nervous system development, neurotrophin TRK receptor signaling pathway, protein phosphorylation, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction, vesicle-mediated transport actin cytoskeleton, cytosol, intracellular ATP binding, Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, metal ion binding, phospholipid binding, protein serine/threonine kinase activity Human KANK1 IntAct UniProtKB {GO:0005515=PMID:19559006, GO:0006355=GO_REF:0000037, GO:0030336=PMID:18458160, GO:0008013=PMID:16968744, GO:2000393=PMID:19171758, GO:0035024=PMID:18458160, GO:0046627=PMID:18458160, GO:0090303=PMID:22084092, GO:2000114=PMID:22084092, GO:0030177=PMID:16968744, GO:0032587=PMID:19559006, GO:0005634=GO_REF:0000039, GO:0035413=PMID:16968744, GO:0006351=GO_REF:0000037, GO:1900028=PMID:19171758, GO:0005737=GO_REF:0000039, GO:1900025=PMID:19171758, GO:0030837=PMID:17996375, GO:0010977=PMID:19171758} Q14678 KN motif and ankyrin repeat domain-containing protein 1 protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0030336=IMP, GO:0008013=IDA, GO:2000393=IDA, GO:0035024=IMP, GO:0046627=IMP, GO:0090303=IMP, GO:2000114=IMP, GO:0030177=IDA, GO:0032587=IDA, GO:0005634=IEA, GO:0035413=IMP, GO:0006351=IEA, GO:1900028=IDA, GO:0005737=IEA, GO:1900025=IDA, GO:0030837=IDA, GO:0010977=IDA} negative regulation of Rho protein signal transduction, negative regulation of actin filament polymerization, negative regulation of cell migration, negative regulation of insulin receptor signaling pathway, negative regulation of lamellipodium morphogenesis, negative regulation of neuron projection development, negative regulation of ruffle assembly, negative regulation of substrate adhesion-dependent cell spreading, positive regulation of Wnt receptor signaling pathway, positive regulation of catenin import into nucleus, positive regulation of wound healing, regulation of establishment of cell polarity, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus, ruffle membrane beta-catenin binding, protein binding Human UniProtKB:Q7Z4S6 KANK2 IntAct UniProtKB {GO:0005515=PMID:22371500, GO:0005739=PMID:22371500, GO:0043069=PMID:22371500, GO:0005737=PMID:17476305, GO:0008285=PMID:17476305, GO:0006915=GO_REF:0000037, GO:2000134=PMID:17476305, GO:0033147=PMID:17476305, GO:0000122=PMID:17476305, GO:0006351=GO_REF:0000037} Q63ZY3 KN motif and ankyrin repeat domain-containing protein 2 protein 20130415 {GO:0005515=IPI, GO:0005739=IDA, GO:0043069=IDA, GO:0005737=IDA, GO:0008285=IDA, GO:0006915=IEA, GO:2000134=IDA, GO:0033147=IDA, GO:0000122=IDA, GO:0006351=IEA} apoptotic process, negative regulation of G1/S transition of mitotic cell cycle, negative regulation of cell proliferation, negative regulation of intracellular estrogen receptor signaling pathway, negative regulation of programmed cell death, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, mitochondrion protein binding Human UniProtKB:O95831 KANK4 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q5T7N3 KN motif and ankyrin repeat domain-containing protein 4 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 KANSL2 UniProtKB UniProtKB {GO:0043981=PMID:20018852, GO:0043982=PMID:20018852, GO:0043984=PMID:20018852, GO:0043996=PMID:20018852, GO:0043995=PMID:20018852, GO:0000123=PMID:20018852, GO:0046972=PMID:20018852} Q9H9L4 KAT8 regulatory NSL complex subunit 2 protein 20120118 {GO:0043981=IDA, GO:0043982=IDA, GO:0043984=IDA, GO:0043996=IDA, GO:0043995=IDA, GO:0000123=IDA, GO:0046972=IDA} histone H4-K16 acetylation, histone H4-K5 acetylation, histone H4-K8 acetylation histone acetyltransferase complex histone acetyltransferase activity (H4-K16 specific), histone acetyltransferase activity (H4-K5 specific), histone acetyltransferase activity (H4-K8 specific) contributes_to Human KANSL3 UniProtKB UniProtKB {GO:0043981=PMID:20018852, GO:0043982=PMID:20018852, GO:0043984=PMID:20018852, GO:0043996=PMID:20018852, GO:0043995=PMID:20018852, GO:0000123=PMID:20018852, GO:0046972=PMID:20018852} Q9P2N6 KAT8 regulatory NSL complex subunit 3 protein 20120118 {GO:0043981=IDA, GO:0043982=IDA, GO:0043984=IDA, GO:0043996=IDA, GO:0043995=IDA, GO:0000123=IDA, GO:0046972=IDA} histone H4-K16 acetylation, histone H4-K5 acetylation, histone H4-K8 acetylation histone acetyltransferase complex histone acetyltransferase activity (H4-K16 specific), histone acetyltransferase activity (H4-K5 specific), histone acetyltransferase activity (H4-K8 specific) contributes_to Human KARS HPA UniProtKB {GO:0010467=Reactome:REACT_71, GO:0000049=PMID:10952987, GO:0005886=GO_REF:0000039, GO:0015966=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0004824=Reactome:REACT_15537, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000019, GO:0008033=PMID:10952987, GO:0017101=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0006418=Reactome:REACT_15482, GO:0005829=Reactome:REACT_15516, GO:0005739=PMID:10952987, GO:0005737=GO_REF:0000052, GO:0005759=Reactome:REACT_15537, GO:0006430=PMID:10952987, GO:0019048=GO_REF:0000037, GO:0015630=GO_REF:0000052, GO:0016597=GO_REF:0000019} Q15046 Lysine--tRNA ligase protein 20111111 {GO:0010467=TAS, GO:0000049=NAS, GO:0005886=IEA, GO:0015966=IEA, GO:0005576=IEA, GO:0005634=IEA, GO:0004824=TAS, GO:0003676=IEA, GO:0005524=IEA, GO:0008033=NAS, GO:0017101=IEA, GO:0046872=IEA, GO:0006418=TAS, GO:0005829=TAS, GO:0005739=IDA, GO:0005737=IDA, GO:0005759=TAS, GO:0006430=IDA, GO:0019048=IEA, GO:0015630=IDA, GO:0016597=IEA} diadenosine tetraphosphate biosynthetic process, gene expression, lysyl-tRNA aminoacylation, tRNA aminoacylation for protein translation, tRNA processing, virus-host interaction aminoacyl-tRNA synthetase multienzyme complex, cytoplasm, cytosol, extracellular region, microtubule cytoskeleton, mitochondrial matrix, mitochondrion, nucleus, plasma membrane ATP binding, amino acid binding, lysine-tRNA ligase activity, metal ion binding, nucleic acid binding, tRNA binding Human KAT2A BHF-UCL UniProtKB {GO:0005515=PMID:21725360, GO:0072686=GO_REF:0000019, GO:0006366=PMID:8552087, GO:0042826=PMID:12887892, GO:0008283=GO_REF:0000019, GO:0001756=GO_REF:0000019, GO:0005634=GO_REF:0000002, GO:0021537=GO_REF:0000019, GO:0031647=PMID:20562830, GO:0035264=GO_REF:0000019, GO:0043997=GO_REF:0000019, GO:0006338=PMID:8552087, GO:0044154=GO_REF:0000019, GO:0004402=PMID:10373431, GO:0016578=PMID:18206972, GO:0006355=GO_REF:0000002, GO:0008080=GO_REF:0000002, GO:0006357=PMID:8552087, GO:0030914=PMID:11564863, GO:0010484=PMID:18838386, GO:0003713=PMID:11564863, GO:0001843=GO_REF:0000019, GO:0042981=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0033276=PMID:10373431, GO:0022037=GO_REF:0000019, GO:0043966=PMID:18838386, GO:0003682=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0005671=PMID:18838386, GO:0030901=GO_REF:0000019} Q92830 Histone acetyltransferase KAT2A protein 20101105 {GO:0005515=IPI, GO:0072686=IEA, GO:0006366=TAS, GO:0042826=IPI, GO:0008283=IEA, GO:0001756=IEA, GO:0005634=IEA, GO:0021537=IEA, GO:0031647=IMP, GO:0035264=IEA, GO:0043997=IEA, GO:0006338=TAS, GO:0044154=IEA, GO:0004402=IDA, GO:0016578=IDA, GO:0006355=IEA, GO:0008080=IEA, GO:0006357=TAS, GO:0030914=IDA, GO:0010484=IDA, GO:0003713=IDA, GO:0001843=IEA, GO:0042981=IEA, GO:0001701=IEA, GO:0033276=IDA, GO:0022037=IEA, GO:0043966=IDA, GO:0003682=IEA, GO:0019048=IEA, GO:0005671=IDA, GO:0030901=IEA} cell proliferation, chromatin remodeling, histone H3 acetylation, histone H3-K14 acetylation, histone deubiquitination, in utero embryonic development, metencephalon development, midbrain development, multicellular organism growth, neural tube closure, regulation of apoptotic process, regulation of protein stability, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, somitogenesis, telencephalon development, transcription from RNA polymerase II promoter, virus-host interaction Ada2/Gcn5/Ada3 transcription activator complex, STAGA complex, mitotic spindle, nucleus, transcription factor TFTC complex H3 histone acetyltransferase activity, N-acetyltransferase activity, chromatin binding, histone acetyltransferase activity, histone acetyltransferase activity (H4-K12 specific), histone deacetylase binding, protein binding, transcription coactivator activity Human KAT2B BHF-UCL UniProtKB {GO:0005515=PMID:19303849, GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_118713, GO:0008285=PMID:8684459, GO:0010835=PMID:19470756, GO:0042641=GO_REF:0000019, GO:0042826=PMID:12887892, GO:0045736=GO_REF:0000019, GO:0006361=Reactome:REACT_1974, GO:0005634=GO_REF:0000024, GO:0006360=Reactome:REACT_1309, GO:0018076=PMID:12435739, GO:0004468=PMID:19303849, GO:0007219=Reactome:REACT_118859, GO:0000125=PMID:18669648, GO:0045944=PMID:19470756, GO:0006338=PMID:10365964, GO:0007050=PMID:8684459, GO:0004402=GO_REF:0000003, GO:0006473=PMID:8684459, GO:0003712=PMID:8684459, GO:0032869=PMID:19303849, GO:0019901=GO_REF:0000024, GO:0003713=PMID:12435739, GO:0018394=PMID:19303849, GO:0043966=PMID:18838386, GO:0019048=GO_REF:0000037, GO:0004861=GO_REF:0000024, GO:0005671=PMID:18838386, GO:0000776=GO_REF:0000019, GO:0016407=PMID:8684459, GO:0005654=Reactome:REACT_160309, GO:0031672=GO_REF:0000019, GO:0008134=PMID:15509593, GO:0031674=GO_REF:0000019} Q92831 Histone acetyltransferase KAT2B protein 20121130 {GO:0005515=IPI, GO:0010467=TAS, GO:0006367=TAS, GO:0008285=IDA, GO:0010835=IDA, GO:0042641=IEA, GO:0042826=IPI, GO:0045736=IEA, GO:0006361=TAS, GO:0005634=ISS, GO:0006360=TAS, GO:0018076=IDA, GO:0004468=IDA, GO:0007219=TAS, GO:0000125=NAS, GO:0045944=IDA, GO:0006338=NAS, GO:0007050=TAS, GO:0004402=IEA, GO:0006473=TAS, GO:0003712=IPI, GO:0032869=IDA, GO:0019901=ISS, GO:0003713=IDA, GO:0018394=IDA, GO:0043966=IDA, GO:0019048=IEA, GO:0004861=ISS, GO:0005671=IDA, GO:0000776=IEA, GO:0016407=IDA, GO:0005654=TAS, GO:0031672=IEA, GO:0008134=IPI, GO:0031674=IEA} N-terminal peptidyl-lysine acetylation, Notch signaling pathway, cell cycle arrest, cellular response to insulin stimulus, chromatin remodeling, gene expression, histone H3 acetylation, negative regulation of cell proliferation, negative regulation of cyclin-dependent protein serine/threonine kinase activity, peptidyl-lysine acetylation, positive regulation of transcription from RNA polymerase II promoter, protein acetylation, regulation of protein ADP-ribosylation, transcription from RNA polymerase I promoter, transcription initiation from RNA polymerase I promoter, transcription initiation from RNA polymerase II promoter, virus-host interaction A band, Ada2/Gcn5/Ada3 transcription activator complex, I band, PCAF complex, actomyosin, kinetochore, nucleoplasm, nucleus acetyltransferase activity, cyclin-dependent protein serine/threonine kinase inhibitor activity, histone acetyltransferase activity, histone deacetylase binding, lysine N-acetyltransferase activity, protein binding, protein kinase binding, transcription coactivator activity, transcription cofactor activity, transcription factor binding Human KAT5 HPA UniProtKB {GO:0005515=PMID:22094252, GO:0016747=GO_REF:0000002, GO:0048471=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0050681=PMID:15572661, GO:0032403=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=GO_REF:0000019, GO:0006302=PMID:10966108, GO:0045944=GO_REF:0000019, GO:0070491=PMID:17360565, GO:0035267=PMID:14966270, GO:0006978=PMID:14966270, GO:0000785=GO_REF:0000019, GO:0004402=PMID:14966270, GO:0032703=PMID:17360565, GO:0005667=GO_REF:0000019, GO:0016573=PMID:10966108, GO:0003713=PMID:17360565, GO:0005730=GO_REF:0000052, GO:0000122=PMID:17360565, GO:0006351=GO_REF:0000037, GO:0032777=PMID:14966270, GO:0019048=GO_REF:0000037, GO:0045893=PMID:14966270, GO:0045892=PMID:17360565, GO:0040008=GO_REF:0000037, GO:0030521=PMID:15572661, GO:0008134=GO_REF:0000019} Q92993 Histone acetyltransferase KAT5 protein 20090616 {GO:0005515=IPI, GO:0016747=IEA, GO:0048471=IEA, GO:0005634=IDA, GO:0050681=NAS, GO:0032403=IEA, GO:0046872=IEA, GO:0005829=IEA, GO:0006302=IMP, GO:0045944=IEA, GO:0070491=IPI, GO:0035267=IDA, GO:0006978=IDA, GO:0000785=IEA, GO:0004402=IDA, GO:0032703=IDA, GO:0005667=IEA, GO:0016573=IDA, GO:0003713=TAS, GO:0005730=IDA, GO:0000122=IMP, GO:0006351=IEA, GO:0032777=IDA, GO:0019048=IEA, GO:0045893=IDA, GO:0045892=IDA, GO:0040008=IEA, GO:0030521=NAS, GO:0008134=IEA} DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, androgen receptor signaling pathway, double-strand break repair, histone acetylation, negative regulation of interleukin-2 production, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of growth, transcription, DNA-dependent, virus-host interaction NuA4 histone acetyltransferase complex, Piccolo NuA4 histone acetyltransferase complex, chromatin, cytosol, nucleolus, nucleus, perinuclear region of cytoplasm, transcription factor complex androgen receptor binding, histone acetyltransferase activity, metal ion binding, protein binding, protein complex binding, repressing transcription factor binding, transcription coactivator activity, transcription factor binding, transferase activity, transferring acyl groups other than amino-acyl groups NOT Human KAT6A PINC UniProtKB {GO:0005515=PMID:23431171, GO:0016747=GO_REF:0000002, GO:0070776=PMID:16387653, GO:0006323=PMID:8782817, GO:0005634=PMID:18794358, GO:0030099=PMID:11742995, GO:0000786=GO_REF:0000002, GO:0035162=GO_REF:0000019, GO:0035019=GO_REF:0000019, GO:0004402=PMID:17925393, GO:0006473=PMID:23431171, GO:0006355=GO_REF:0000002, GO:0016573=PMID:17925393, GO:0003713=PMID:18794358, GO:0005730=GO_REF:0000039, GO:0006334=GO_REF:0000002, GO:0003677=PMID:17925393, GO:0006351=GO_REF:0000037, GO:0043966=PMID:16387653, GO:0016605=PMID:23431171, GO:0016407=PMID:11742995, GO:0008270=PMID:17925393, GO:0045893=PMID:11965546, GO:0045892=PMID:11742995, GO:0008134=PMID:11965546, GO:0090398=PMID:23431171} Q92794 Histone acetyltransferase KAT6A protein 20030904 {GO:0005515=IPI, GO:0016747=IEA, GO:0070776=IDA, GO:0006323=TAS, GO:0005634=IDA, GO:0030099=IDA, GO:0000786=IEA, GO:0035162=IEA, GO:0035019=IEA, GO:0004402=IDA, GO:0006473=IDA, GO:0006355=IEA, GO:0016573=IDA, GO:0003713=TAS, GO:0005730=IEA, GO:0006334=IEA, GO:0003677=IDA, GO:0006351=IEA, GO:0043966=IDA, GO:0016605=IDA, GO:0016407=IDA, GO:0008270=IDA, GO:0045893=IDA, GO:0045892=IDA, GO:0008134=IDA, GO:0090398=IMP} DNA packaging, cellular senescence, embryonic hemopoiesis, histone H3 acetylation, histone acetylation, myeloid cell differentiation, negative regulation of transcription, DNA-dependent, nucleosome assembly, positive regulation of transcription, DNA-dependent, protein acetylation, regulation of transcription, DNA-dependent, somatic stem cell maintenance, transcription, DNA-dependent MOZ/MORF histone acetyltransferase complex, PML body, nucleolus, nucleosome, nucleus DNA binding, acetyltransferase activity, histone acetyltransferase activity, protein binding, transcription coactivator activity, transcription factor binding, transferase activity, transferring acyl groups other than amino-acyl groups, zinc ion binding Human KAT6B HPA UniProtKB {GO:0005515=PMID:11965546, GO:0006355=PMID:10497217, GO:0070776=PMID:16387653, GO:0016573=PMID:11965546, GO:0006334=PMID:10497217, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0043966=PMID:16387653, GO:0008270=GO_REF:0000002, GO:0016407=PMID:11965546, GO:0000786=PMID:10497217, GO:0045893=PMID:10497217, GO:0045892=PMID:10497217, GO:0004402=PMID:10497217, GO:0008134=PMID:11965546} Q8WYB5 Histone acetyltransferase KAT6B protein 20080205 {GO:0005515=IPI, GO:0006355=NAS, GO:0070776=IDA, GO:0016573=IDA, GO:0006334=NAS, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA, GO:0043966=IDA, GO:0008270=IEA, GO:0016407=IDA, GO:0000786=NAS, GO:0045893=IDA, GO:0045892=IDA, GO:0004402=IDA, GO:0008134=IDA} histone H3 acetylation, histone acetylation, negative regulation of transcription, DNA-dependent, nucleosome assembly, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent MOZ/MORF histone acetyltransferase complex, nucleosome, nucleus DNA binding, acetyltransferase activity, histone acetyltransferase activity, protein binding, transcription factor binding, zinc ion binding Human KAT7 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0006355=PMID:10438470, GO:0016747=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0005730=PMID:16387653, GO:0005634=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0043981=PMID:16387653, GO:0006260=PMID:16387653, GO:0043983=PMID:16387653, GO:0043982=PMID:16387653, GO:0043966=PMID:16387653, GO:0043984=PMID:16387653, GO:0000123=PMID:16387653, GO:0005654=PMID:16387653, GO:0008270=GO_REF:0000002, GO:0004402=GO_REF:0000003} O95251 Histone acetyltransferase KAT7 protein 20130415 {GO:0005515=IPI, GO:0006355=TAS, GO:0016747=IEA, GO:0003700=IEA, GO:0005730=IDA, GO:0005634=IEA, GO:0006351=IEA, GO:0043981=IDA, GO:0006260=IDA, GO:0043983=IDA, GO:0043982=IDA, GO:0043966=IDA, GO:0043984=IDA, GO:0000123=IDA, GO:0005654=IDA, GO:0008270=IEA, GO:0004402=IEA} DNA replication, histone H3 acetylation, histone H4-K12 acetylation, histone H4-K16 acetylation, histone H4-K5 acetylation, histone H4-K8 acetylation, regulation of transcription, DNA-dependent, transcription, DNA-dependent histone acetyltransferase complex, nucleolus, nucleoplasm, nucleus histone acetyltransferase activity, protein binding, sequence-specific DNA binding transcription factor activity, transferase activity, transferring acyl groups other than amino-acyl groups, zinc ion binding Human UniProtKB:P08670 KAT8 IntAct UniProtKB {GO:0005515=PMID:15960975, GO:0016747=GO_REF:0000002, GO:0005634=PMID:11742995, GO:0035064=PMID:15960975, GO:0046872=GO_REF:0000037, GO:0071339=PMID:15960975, GO:0043996=PMID:20018852, GO:0000123=PMID:20018852, GO:0043995=PMID:20018852, GO:0072487=PMID:20018852, GO:0030099=PMID:11742995, GO:0004402=PMID:11742995, GO:0006355=GO_REF:0000002, GO:0016573=PMID:11742995, GO:0006351=GO_REF:0000037, GO:0043981=PMID:20018852, GO:0043982=PMID:20018852, GO:0043984=PMID:20018852, GO:0000776=GO_REF:0000019, GO:0016407=PMID:11742995, GO:0046972=PMID:20018852, GO:0045893=PMID:15960975, GO:0019899=GO_REF:0000019, GO:0045892=PMID:11742995, GO:0008134=PMID:11742995} Q9H7Z6 Histone acetyltransferase KAT8 protein 20130415 {GO:0005515=IPI, GO:0016747=IEA, GO:0005634=IDA, GO:0035064=IDA, GO:0046872=IEA, GO:0071339=IDA, GO:0043996=IDA, GO:0000123=IDA, GO:0043995=IDA, GO:0072487=IDA, GO:0030099=IDA, GO:0004402=IDA, GO:0006355=IEA, GO:0016573=IDA, GO:0006351=IEA, GO:0043981=IDA, GO:0043982=IDA, GO:0043984=IDA, GO:0000776=IEA, GO:0016407=IDA, GO:0046972=IDA, GO:0045893=IMP, GO:0019899=IEA, GO:0045892=IDA, GO:0008134=IDA} histone H4-K16 acetylation, histone H4-K5 acetylation, histone H4-K8 acetylation, histone acetylation, myeloid cell differentiation, negative regulation of transcription, DNA-dependent, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent MLL1 complex, MSL complex, histone acetyltransferase complex, kinetochore, nucleus acetyltransferase activity, enzyme binding, histone acetyltransferase activity, histone acetyltransferase activity (H4-K16 specific), histone acetyltransferase activity (H4-K5 specific), histone acetyltransferase activity (H4-K8 specific), metal ion binding, methylated histone residue binding, protein binding, transcription factor binding, transferase activity, transferring acyl groups other than amino-acyl groups Human UniProtKB:Q99496 KATNA1 HPA UniProtKB {GO:0005515=PMID:19261606, GO:0008017=PMID:10751153, GO:0030424=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0001578=GO_REF:0000019, GO:0031122=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0030426=GO_REF:0000019, GO:0051013=GO_REF:0000019, GO:0005737=PMID:19261606, GO:0008104=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0016887=GO_REF:0000019, GO:0005811=GO_REF:0000019, GO:0005813=GO_REF:0000052, GO:0046982=PMID:10751153, GO:0005874=GO_REF:0000037, GO:0005819=PMID:19261606, GO:0030496=PMID:19261606, GO:0051329=PMID:10751153, GO:0005524=GO_REF:0000037, GO:0008568=PMID:10751153, GO:0007067=GO_REF:0000037, GO:0000922=PMID:19261606, GO:0045502=GO_REF:0000019, GO:0010977=GO_REF:0000019, GO:0001764=GO_REF:0000019, GO:0051301=GO_REF:0000037} O75449 Katanin p60 ATPase-containing subunit A1 protein 20110516 {GO:0005515=IPI, GO:0008017=IDA, GO:0030424=IEA, GO:0005886=IEA, GO:0001578=IEA, GO:0031122=IEA, GO:0005634=IDA, GO:0030426=IEA, GO:0051013=IEA, GO:0005737=IDA, GO:0008104=IEA, GO:0043025=IEA, GO:0016887=IEA, GO:0005811=IEA, GO:0005813=IDA, GO:0046982=IPI, GO:0005874=IEA, GO:0005819=IDA, GO:0030496=IDA, GO:0051329=IMP, GO:0005524=IEA, GO:0008568=IDA, GO:0007067=IEA, GO:0000922=IDA, GO:0045502=IEA, GO:0010977=IEA, GO:0001764=IEA, GO:0051301=IEA} cell division, cytoplasmic microtubule organization, interphase of mitotic cell cycle, microtubule bundle formation, microtubule severing, mitosis, negative regulation of neuron projection development, neuron migration, protein localization axon, centrosome, cytoplasm, growth cone, lipid particle, microtubule, midbody, neuronal cell body, nucleus, plasma membrane, spindle, spindle pole ATP binding, ATPase activity, dynein binding, microtubule binding, microtubule-severing ATPase activity, protein binding, protein heterodimerization activity Human KATNAL1 UniProtKB UniProtKB {GO:0008568=GO_REF:0000003, GO:0005737=GO_REF:0000037, GO:0005874=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q9BW62 Katanin p60 ATPase-containing subunit A-like 1 protein 20130413 {GO:0008568=IEA, GO:0005737=IEA, GO:0005874=IEA, GO:0005524=IEA} cytoplasm, microtubule ATP binding, microtubule-severing ATPase activity Human EC:3.6.4.3 KATNAL2 UniProtKB UniProtKB {GO:0008568=GO_REF:0000003, GO:0005737=GO_REF:0000037, GO:0017111=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q8IYT4 Katanin p60 ATPase-containing subunit A-like 2 protein 20130413 {GO:0008568=IEA, GO:0005737=IEA, GO:0017111=IEA, GO:0005874=IEA, GO:0005524=IEA} cytoplasm, microtubule ATP binding, microtubule-severing ATPase activity, nucleoside-triphosphatase activity Human EC:3.6.4.3 KATNB1 HPA UniProtKB {GO:0008017=PMID:10751153, GO:0030424=GO_REF:0000019, GO:0005813=GO_REF:0000019, GO:0031117=PMID:10751153, GO:0005886=GO_REF:0000052, GO:0046982=PMID:10751153, GO:0005874=GO_REF:0000037, GO:0030496=GO_REF:0000019, GO:0006605=PMID:10751153, GO:0008352=PMID:9568719, GO:0030426=GO_REF:0000019, GO:0008568=PMID:10751153, GO:0051013=GO_REF:0000019, GO:0000922=PMID:10751153, GO:0005737=GO_REF:0000052, GO:0007067=GO_REF:0000037, GO:0045502=GO_REF:0000019, GO:0015630=GO_REF:0000052, GO:0010976=GO_REF:0000019, GO:0007026=PMID:10751153, GO:0043025=GO_REF:0000019, GO:0010942=GO_REF:0000019, GO:0051301=GO_REF:0000037} Q9BVA0 Katanin p80 WD40 repeat-containing subunit B1 protein 20111111 {GO:0008017=NAS, GO:0030424=IEA, GO:0005813=IEA, GO:0031117=IMP, GO:0005886=IDA, GO:0046982=IPI, GO:0005874=IEA, GO:0030496=IEA, GO:0006605=NAS, GO:0008352=IDA, GO:0030426=IEA, GO:0008568=IDA, GO:0051013=IEA, GO:0000922=IDA, GO:0005737=IDA, GO:0007067=IEA, GO:0045502=IEA, GO:0015630=IDA, GO:0010976=IEA, GO:0007026=IMP, GO:0043025=IEA, GO:0010942=IEA, GO:0051301=IEA} cell division, microtubule severing, mitosis, negative regulation of microtubule depolymerization, positive regulation of cell death, positive regulation of microtubule depolymerization, positive regulation of neuron projection development, protein targeting axon, centrosome, cytoplasm, growth cone, katanin complex, microtubule, microtubule cytoskeleton, midbody, neuronal cell body, plasma membrane, spindle pole dynein binding, microtubule binding, microtubule-severing ATPase activity, protein heterodimerization activity Human KAZN HPA UniProtKB {GO:0030057=PMID:15337775, GO:0031965=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0031424=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0001533=PMID:15337775, GO:0043231=GO_REF:0000052} Q674X7 Kazrin protein 20110516 {GO:0030057=IDA, GO:0031965=IDA, GO:0005737=IDA, GO:0031424=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0001533=IDA, GO:0043231=IDA} keratinization cornified envelope, cytoplasm, desmosome, intracellular membrane-bounded organelle, nuclear membrane, nucleolus, nucleus Human KBTBD11 null null {} null null null null {} null null null KBTBD13 UniPathway UniProtKB {GO:0005737=GO_REF:0000039, GO:0016567=GO_REF:0000041} C9JR72 Kelch repeat and BTB domain-containing protein 13 protein 20130413 {GO:0005737=IEA, GO:0016567=IEA} protein ubiquitination cytoplasm Human UniPathway:UPA00143 KBTBD2 null null {} null null null null {} null null null KBTBD3 null null {} null null null null {} null null null KBTBD4 null null {} null null null null {} null null null KBTBD6 IntAct UniProtKB {GO:0005515=PMID:20562859, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q86V97 Kelch repeat and BTB domain-containing protein 6 protein 20130415 {GO:0005515=IPI, GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function, protein binding Human UniProtKB:Q9H0R8 KBTBD7 IntAct UniProtKB {GO:0005515=PMID:20562859, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q8WVZ9 Kelch repeat and BTB domain-containing protein 7 protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function, protein binding Human UniProtKB:Q9H0R8 KBTBD8 null null {} null null null null {} null null null KCMF1 UniProtKB UniProtKB {GO:0016874=GO_REF:0000037, GO:0008270=GO_REF:0000002} Q9P0J7 E3 ubiquitin-protein ligase KCMF1 protein 20130413 {GO:0016874=IEA, GO:0008270=IEA} ligase activity, zinc ion binding Human UniProtKB-KW:KW-0436 KCNA1 BHF-UCL UniProtKB {GO:0005251=GO_REF:0000033, GO:0015079=PMID:8845167, GO:0016324=GO_REF:0000019, GO:0005886=Reactome:REACT_75857, GO:0044224=GO_REF:0000024, GO:0008076=GO_REF:0000002, GO:0043025=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0005267=PMID:7842011, GO:0051260=GO_REF:0000002, GO:0006813=PMID:8845167, GO:0030425=GO_REF:0000019} Q09470 Potassium voltage-gated channel subfamily A member 1 protein 20091117 {GO:0005251=IBA, GO:0015079=TAS, GO:0016324=IEA, GO:0005886=TAS, GO:0044224=ISS, GO:0008076=IEA, GO:0043025=IEA, GO:0007268=TAS, GO:0005267=TAS, GO:0051260=IEA, GO:0006813=TAS, GO:0030425=IEA} potassium ion transport, protein homooligomerization, synaptic transmission apical plasma membrane, dendrite, juxtaparanode region of axon, neuronal cell body, plasma membrane, voltage-gated potassium channel complex delayed rectifier potassium channel activity, potassium channel activity, potassium ion transmembrane transporter activity Human UniProtKB:P16388 KCNA10 Reactome UniProtKB {GO:0005251=GO_REF:0000033, GO:0005886=Reactome:REACT_75857, GO:0005221=PMID:9177773, GO:0008076=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0051260=GO_REF:0000002, GO:0006813=PMID:9177773} Q16322 Potassium voltage-gated channel subfamily A member 10 protein 20130301 {GO:0005251=IBA, GO:0005886=TAS, GO:0005221=TAS, GO:0008076=IEA, GO:0007268=TAS, GO:0051260=IEA, GO:0006813=TAS} potassium ion transport, protein homooligomerization, synaptic transmission plasma membrane, voltage-gated potassium channel complex delayed rectifier potassium channel activity, intracellular cyclic nucleotide activated cation channel activity Human KCNA2 BHF-UCL UniProtKB {GO:0005251=PMID:1715584, GO:0015271=GO_REF:0000019, GO:0005886=Reactome:REACT_75857, GO:0044224=GO_REF:0000024, GO:0005249=PMID:2251283, GO:0008076=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0005267=PMID:2722779, GO:0051260=GO_REF:0000002, GO:0021633=GO_REF:0000019, GO:0006813=PMID:2251283} P16389 Potassium voltage-gated channel subfamily A member 2 protein 20091117 {GO:0005251=TAS, GO:0015271=IEA, GO:0005886=TAS, GO:0044224=ISS, GO:0005249=TAS, GO:0008076=IEA, GO:0007268=TAS, GO:0005267=TAS, GO:0051260=IEA, GO:0021633=IEA, GO:0006813=TAS} optic nerve structural organization, potassium ion transport, protein homooligomerization, synaptic transmission juxtaparanode region of axon, plasma membrane, voltage-gated potassium channel complex delayed rectifier potassium channel activity, outward rectifier potassium channel activity, potassium channel activity, voltage-gated potassium channel activity Human UniProtKB:P63141 KCNA3 Reactome UniProtKB {GO:0005251=GO_REF:0000033, GO:0015271=GO_REF:0000019, GO:0005244=PMID:1373731, GO:0005886=Reactome:REACT_75857, GO:0008076=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0045121=GO_REF:0000019, GO:0051260=GO_REF:0000002, GO:0006813=PMID:1373731} P22001 Potassium voltage-gated channel subfamily A member 3 protein 20130301 {GO:0005251=IBA, GO:0015271=IEA, GO:0005244=TAS, GO:0005886=TAS, GO:0008076=IEA, GO:0007268=TAS, GO:0045121=IEA, GO:0051260=IEA, GO:0006813=TAS} potassium ion transport, protein homooligomerization, synaptic transmission membrane raft, plasma membrane, voltage-gated potassium channel complex delayed rectifier potassium channel activity, outward rectifier potassium channel activity, voltage-gated ion channel activity Human KCNA4 Reactome UniProtKB {GO:0005515=PMID:7477295, GO:0005251=GO_REF:0000033, GO:0005886=Reactome:REACT_75857, GO:0005249=PMID:2001794, GO:0008076=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0051260=GO_REF:0000002, GO:0030955=GO_REF:0000002, GO:0006813=PMID:2001794} P22459 Potassium voltage-gated channel subfamily A member 4 protein 20130301 {GO:0005515=IPI, GO:0005251=IBA, GO:0005886=TAS, GO:0005249=TAS, GO:0008076=IEA, GO:0007268=TAS, GO:0051260=IEA, GO:0030955=IEA, GO:0006813=TAS} potassium ion transport, protein homooligomerization, synaptic transmission plasma membrane, voltage-gated potassium channel complex delayed rectifier potassium channel activity, potassium ion binding, protein binding, voltage-gated potassium channel activity Human KCNA5 BHF-UCL UniProtKB {GO:0005251=PMID:19343045, GO:0005886=PMID:7615797, GO:0055075=GO_REF:0000019, GO:0043267=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0043266=PMID:12021261, GO:0086091=PMID:19343045, GO:0019229=GO_REF:0000019, GO:0071435=PMID:16236819, GO:0015271=PMID:16236819, GO:0060372=PMID:19343045, GO:0086089=PMID:19343045, GO:0008076=PMID:1986382, GO:0042391=PMID:1986382, GO:0097110=PMID:12970345, GO:0051260=GO_REF:0000002, GO:0006813=PMID:8576199, GO:0001666=GO_REF:0000019, GO:0005794=PMID:16780588, GO:0051481=GO_REF:0000019, GO:0005102=GO_REF:0000019, GO:0060081=PMID:16236819, GO:0050796=PMID:1986382, GO:0051393=PMID:10812072, GO:0005901=PMID:17060380, GO:0019870=GO_REF:0000019, GO:0086014=PMID:19343045, GO:0045121=PMID:18218624} P22460 Potassium voltage-gated channel subfamily A member 5 protein 20120920 {GO:0005251=IMP, GO:0005886=IDA, GO:0055075=IEA, GO:0043267=IEA, GO:0007268=TAS, GO:0043266=IMP, GO:0086091=IMP, GO:0019229=IEA, GO:0071435=IMP, GO:0015271=IMP, GO:0060372=IMP, GO:0086089=IMP, GO:0008076=IDA, GO:0042391=IDA, GO:0097110=IPI, GO:0051260=IEA, GO:0006813=IDA, GO:0001666=IEA, GO:0005794=IDA, GO:0051481=IEA, GO:0005102=IEA, GO:0060081=IMP, GO:0050796=TAS, GO:0051393=IPI, GO:0005901=TAS, GO:0019870=IEA, GO:0086014=IMP, GO:0045121=IDA} membrane hyperpolarization, negative regulation of potassium ion transport, potassium ion export, potassium ion homeostasis, potassium ion transport, protein homooligomerization, reduction of cytosolic calcium ion concentration, regulation of atrial cardiac muscle cell action potential, regulation of atrial cardiac muscle cell membrane repolarization, regulation of heart rate by cardiac conduction, regulation of insulin secretion, regulation of membrane potential, regulation of potassium ion transport, regulation of vasoconstriction, response to hypoxia, synaptic transmission Golgi apparatus, caveola, membrane raft, plasma membrane, voltage-gated potassium channel complex alpha-actinin binding, delayed rectifier potassium channel activity, outward rectifier potassium channel activity, potassium channel inhibitor activity, receptor binding, scaffold protein binding, voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization Human KCNA6 Reactome UniProtKB {GO:0005251=GO_REF:0000033, GO:0005886=Reactome:REACT_75857, GO:0005249=PMID:2347305, GO:0008076=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0051260=GO_REF:0000002, GO:0006813=PMID:2347305} P17658 Potassium voltage-gated channel subfamily A member 6 protein 20130301 {GO:0005251=IBA, GO:0005886=TAS, GO:0005249=TAS, GO:0008076=IEA, GO:0007268=TAS, GO:0051260=IEA, GO:0006813=TAS} potassium ion transport, protein homooligomerization, synaptic transmission plasma membrane, voltage-gated potassium channel complex delayed rectifier potassium channel activity, voltage-gated potassium channel activity Human KCNAB1 Reactome UniProtKB {GO:0005737=GO_REF:0000039, GO:0005886=Reactome:REACT_75857, GO:0005249=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0015459=PMID:7499366, GO:0016021=GO_REF:0000002, GO:0055085=GO_REF:0000002, GO:0006813=PMID:7499366} Q14722 Voltage-gated potassium channel subunit beta-1 protein 20130301 {GO:0005737=IEA, GO:0005886=TAS, GO:0005249=IEA, GO:0007268=TAS, GO:0015459=TAS, GO:0016021=IEA, GO:0055085=IEA, GO:0006813=TAS} potassium ion transport, synaptic transmission, transmembrane transport cytoplasm, integral to membrane, plasma membrane potassium channel regulator activity, voltage-gated potassium channel activity Human KCNAB2 InterPro UniProtKB {GO:0005737=GO_REF:0000002, GO:0005886=Reactome:REACT_75857, GO:0044224=GO_REF:0000024, GO:0005249=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0015459=PMID:7649300, GO:0016021=GO_REF:0000002, GO:0051291=GO_REF:0000019} Q5TG84 Voltage-gated potassium channel subunit beta-2 protein 20130413 {GO:0005737=IEA, GO:0005886=TAS, GO:0044224=ISS, GO:0005249=IEA, GO:0007268=TAS, GO:0015459=TAS, GO:0016021=IEA, GO:0051291=IEA} protein heterooligomerization, synaptic transmission cytoplasm, integral to membrane, juxtaparanode region of axon, plasma membrane potassium channel regulator activity, voltage-gated potassium channel activity Human InterPro:IPR005401 KCNAB3 Reactome UniProtKB {GO:0005737=GO_REF:0000039, GO:0005886=Reactome:REACT_75857, GO:0005249=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0015459=PMID:9857044, GO:0016021=GO_REF:0000002, GO:0006813=PMID:9857044} O43448 Voltage-gated potassium channel subunit beta-3 protein 20130301 {GO:0005737=IEA, GO:0005886=TAS, GO:0005249=IEA, GO:0007268=TAS, GO:0015459=TAS, GO:0016021=IEA, GO:0006813=TAS} potassium ion transport, synaptic transmission cytoplasm, integral to membrane, plasma membrane potassium channel regulator activity, voltage-gated potassium channel activity Human KCNB1 Reactome UniProtKB {GO:0005251=GO_REF:0000033, GO:0005515=PMID:10484328, GO:0005886=Reactome:REACT_75857, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0030425=GO_REF:0000019, GO:0032809=GO_REF:0000019, GO:0015271=GO_REF:0000019, GO:0032590=GO_REF:0000019, GO:0047485=GO_REF:0000019, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0008076=GO_REF:0000002, GO:0045211=GO_REF:0000019, GO:0051260=GO_REF:0000002} Q14721 Potassium voltage-gated channel subfamily B member 1 protein 20130301 {GO:0005251=IBA, GO:0005515=IPI, GO:0005886=TAS, GO:0007268=TAS, GO:0044281=TAS, GO:0030425=IEA, GO:0032809=IEA, GO:0015271=IEA, GO:0032590=IEA, GO:0047485=IEA, GO:0006112=TAS, GO:0050796=TAS, GO:0008076=IEA, GO:0045211=IEA, GO:0051260=IEA} energy reserve metabolic process, protein homooligomerization, regulation of insulin secretion, small molecule metabolic process, synaptic transmission dendrite, dendrite membrane, neuronal cell body membrane, plasma membrane, postsynaptic membrane, voltage-gated potassium channel complex delayed rectifier potassium channel activity, outward rectifier potassium channel activity, protein N-terminus binding, protein binding Human KCNB2 Reactome UniProtKB {GO:0005251=PMID:9612272, GO:0005886=Reactome:REACT_75857, GO:0008076=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0051260=GO_REF:0000002, GO:0006940=PMID:9612272, GO:0006813=PMID:9612272} Q92953 Potassium voltage-gated channel subfamily B member 2 protein 20130301 {GO:0005251=TAS, GO:0005886=TAS, GO:0008076=IEA, GO:0007268=TAS, GO:0051260=IEA, GO:0006940=TAS, GO:0006813=TAS} potassium ion transport, protein homooligomerization, regulation of smooth muscle contraction, synaptic transmission plasma membrane, voltage-gated potassium channel complex delayed rectifier potassium channel activity Human KCNC1 Reactome UniProtKB {GO:0005251=GO_REF:0000033, GO:0005886=Reactome:REACT_75857, GO:0008076=GO_REF:0000002, GO:0005249=PMID:8449507, GO:0007268=Reactome:REACT_13685, GO:0051260=GO_REF:0000002, GO:0006813=PMID:8449507} P48547 Potassium voltage-gated channel subfamily C member 1 protein 20130301 {GO:0005251=IBA, GO:0005886=TAS, GO:0008076=IEA, GO:0005249=TAS, GO:0007268=TAS, GO:0051260=IEA, GO:0006813=TAS} potassium ion transport, protein homooligomerization, synaptic transmission plasma membrane, voltage-gated potassium channel complex delayed rectifier potassium channel activity, voltage-gated potassium channel activity Human KCNC2 Reactome UniProtKB {GO:0005251=GO_REF:0000033, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0005886=Reactome:REACT_75857, GO:0008076=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0051260=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0001508=GO_REF:0000019} Q96PR1 Potassium voltage-gated channel subfamily C member 2 protein 20130301 {GO:0005251=IBA, GO:0006112=TAS, GO:0050796=TAS, GO:0005886=TAS, GO:0008076=IEA, GO:0007268=TAS, GO:0051260=IEA, GO:0044281=TAS, GO:0001508=IEA} energy reserve metabolic process, protein homooligomerization, regulation of action potential, regulation of insulin secretion, small molecule metabolic process, synaptic transmission plasma membrane, voltage-gated potassium channel complex delayed rectifier potassium channel activity Human KCNC3 Reactome UniProtKB {GO:0005251=GO_REF:0000033, GO:0008219=GO_REF:0000037, GO:0031594=GO_REF:0000019, GO:0005886=Reactome:REACT_75857, GO:0007268=Reactome:REACT_13685, GO:0046928=GO_REF:0000019, GO:0032809=GO_REF:0000019, GO:0032590=GO_REF:0000019, GO:0005249=PMID:1740329, GO:0008076=GO_REF:0000002, GO:0051260=GO_REF:0000002, GO:0043679=GO_REF:0000019, GO:0030673=GO_REF:0000019, GO:0006813=PMID:1740329} Q14003 Potassium voltage-gated channel subfamily C member 3 protein 20130301 {GO:0005251=IBA, GO:0008219=IEA, GO:0031594=IEA, GO:0005886=TAS, GO:0007268=TAS, GO:0046928=IEA, GO:0032809=IEA, GO:0032590=IEA, GO:0005249=TAS, GO:0008076=IEA, GO:0051260=IEA, GO:0043679=IEA, GO:0030673=IEA, GO:0006813=TAS} cell death, potassium ion transport, protein homooligomerization, regulation of neurotransmitter secretion, synaptic transmission axolemma, axon terminus, dendrite membrane, neuromuscular junction, neuronal cell body membrane, plasma membrane, voltage-gated potassium channel complex delayed rectifier potassium channel activity, voltage-gated potassium channel activity Human KCND1 Reactome UniProtKB {GO:0005251=GO_REF:0000033, GO:0005886=Reactome:REACT_75857, GO:0008076=GO_REF:0000002, GO:0005249=GO_REF:0000029, GO:0007268=Reactome:REACT_13685, GO:0051260=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0006813=GO_REF:0000029, GO:0030425=GO_REF:0000039, GO:0046872=GO_REF:0000037} Q9NSA2 Potassium voltage-gated channel subfamily D member 1 protein 20130301 {GO:0005251=IBA, GO:0005886=TAS, GO:0008076=IEA, GO:0005249=NAS, GO:0007268=TAS, GO:0051260=IEA, GO:0005575=ND, GO:0006813=NAS, GO:0030425=IEA, GO:0046872=IEA} potassium ion transport, protein homooligomerization, synaptic transmission cellular_component, dendrite, plasma membrane, voltage-gated potassium channel complex delayed rectifier potassium channel activity, metal ion binding, voltage-gated potassium channel activity Human KCND2 IntAct UniProtKB {GO:0005515=PMID:15358149, GO:0005251=GO_REF:0000033, GO:0005250=GO_REF:0000033, GO:0005886=Reactome:REACT_75857, GO:0009986=PMID:12493773, GO:0043197=PMID:11102480, GO:0008076=GO_REF:0000002, GO:0005249=PMID:11102480, GO:0007268=Reactome:REACT_13685, GO:0051260=GO_REF:0000002, GO:0001508=PMID:11102480, GO:0046872=GO_REF:0000037} Q9NZV8 Potassium voltage-gated channel subfamily D member 2 protein 20130415 {GO:0005515=IPI, GO:0005251=IBA, GO:0005250=IBA, GO:0005886=TAS, GO:0009986=IDA, GO:0043197=NAS, GO:0008076=IEA, GO:0005249=NAS, GO:0007268=TAS, GO:0051260=IEA, GO:0001508=TAS, GO:0046872=IEA} protein homooligomerization, regulation of action potential, synaptic transmission cell surface, dendritic spine, plasma membrane, voltage-gated potassium channel complex A-type (transient outward) potassium channel activity, delayed rectifier potassium channel activity, metal ion binding, protein binding, voltage-gated potassium channel activity Human UniProtKB:Q9NS61-3 KCND3 Reactome UniProtKB {GO:0005251=GO_REF:0000033, GO:0042383=GO_REF:0000039, GO:0005250=GO_REF:0000033, GO:0005886=Reactome:REACT_75857, GO:0008076=GO_REF:0000002, GO:0043025=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0051260=GO_REF:0000002, GO:0006813=PMID:8734615, GO:0030425=GO_REF:0000039, GO:0046872=GO_REF:0000037} Q9UK17 Potassium voltage-gated channel subfamily D member 3 protein 20130301 {GO:0005251=IBA, GO:0042383=IEA, GO:0005250=IBA, GO:0005886=TAS, GO:0008076=IEA, GO:0043025=IEA, GO:0007268=TAS, GO:0051260=IEA, GO:0006813=TAS, GO:0030425=IEA, GO:0046872=IEA} potassium ion transport, protein homooligomerization, synaptic transmission dendrite, neuronal cell body, plasma membrane, sarcolemma, voltage-gated potassium channel complex A-type (transient outward) potassium channel activity, delayed rectifier potassium channel activity, metal ion binding Human KCNE1 BHF-UCL UniProtKB {GO:0005251=PMID:8900283, GO:0060047=GO_REF:0000019, GO:0051899=PMID:8900283, GO:0005886=PMID:16780588, GO:0007605=PMID:9020846, GO:0008015=PMID:9020846, GO:0008016=PMID:8900283, GO:0031433=PMID:11697903, GO:0015459=PMID:8900283, GO:0086091=GO_REF:0000019, GO:0005764=PMID:16780588, GO:1901381=PMID:8900283, GO:0071435=PMID:17289006, GO:0016324=GO_REF:0000019, GO:0006936=PMID:9020846, GO:0006493=PMID:21669976, GO:0005249=PMID:17289006, GO:0008076=PMID:17289006, GO:0002070=GO_REF:0000019, GO:0006487=PMID:21669976, GO:0071805=PMID:8900283} P15382 Potassium voltage-gated channel subfamily E member 1 protein 20120928 {GO:0005251=IDA, GO:0060047=IEA, GO:0051899=IDA, GO:0005886=IDA, GO:0007605=TAS, GO:0008015=NAS, GO:0008016=IC, GO:0031433=IPI, GO:0015459=IDA, GO:0086091=IEA, GO:0005764=IDA, GO:1901381=IDA, GO:0071435=IDA, GO:0016324=IEA, GO:0006936=TAS, GO:0006493=IDA, GO:0005249=IDA, GO:0008076=IDA, GO:0002070=IEA, GO:0006487=IDA, GO:0071805=IDA} blood circulation, epithelial cell maturation, heart contraction, membrane depolarization, muscle contraction, positive regulation of potassium ion transmembrane transport, potassium ion export, potassium ion transmembrane transport, protein N-linked glycosylation, protein O-linked glycosylation, regulation of heart contraction, regulation of heart rate by cardiac conduction, sensory perception of sound apical plasma membrane, lysosome, plasma membrane, voltage-gated potassium channel complex delayed rectifier potassium channel activity, potassium channel regulator activity, telethonin binding, voltage-gated potassium channel activity Human KCNE1L PINC UniProtKB {GO:0008076=PMID:10493825, GO:0008016=PMID:10493825} Q9UJ90 Potassium voltage-gated channel subfamily E member 1-like protein protein 20030904 {GO:0008076=TAS, GO:0008016=TAS} regulation of heart contraction voltage-gated potassium channel complex Human KCNE2 PINC UniProtKB {GO:0006936=PMID:10219239, GO:0005886=PMID:16780588, GO:0008015=PMID:10219239, GO:0008076=GO_REF:0000019, GO:0005249=GO_REF:0000019, GO:0008016=PMID:10219239, GO:0015459=GO_REF:0000019, GO:0060307=GO_REF:0000019, GO:0034613=GO_REF:0000019, GO:0006813=PMID:10219239, GO:0005764=PMID:16780588, GO:0086005=GO_REF:0000019} Q9Y6J6 Potassium voltage-gated channel subfamily E member 2 protein 20030904 {GO:0006936=TAS, GO:0005886=IDA, GO:0008015=NAS, GO:0008076=IEA, GO:0005249=IEA, GO:0008016=TAS, GO:0015459=IEA, GO:0060307=IEA, GO:0034613=IEA, GO:0006813=TAS, GO:0005764=IDA, GO:0086005=IEA} blood circulation, cellular protein localization, muscle contraction, potassium ion transport, regulation of heart contraction, regulation of ventricular cardiac muscle cell action potential, regulation of ventricular cardiac muscle cell membrane repolarization lysosome, plasma membrane, voltage-gated potassium channel complex potassium channel regulator activity, voltage-gated potassium channel activity Human KCNE3 ENSEMBL UniProtKB {GO:0016020=GO_REF:0000002, GO:0005249=GO_REF:0000002, GO:0015459=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0043266=GO_REF:0000019} Q9Y6H6 Potassium voltage-gated channel subfamily E member 3 protein 20130413 {GO:0016020=IEA, GO:0005249=IEA, GO:0015459=IEA, GO:0016021=IEA, GO:0043266=IEA} regulation of potassium ion transport integral to membrane, membrane potassium channel regulator activity, voltage-gated potassium channel activity Human Ensembl:ENSRNOP00000044706 KCNE4 ENSEMBL UniProtKB {GO:0016324=GO_REF:0000019, GO:0005249=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q8WWG9 Potassium voltage-gated channel subfamily E member 4 protein 20130413 {GO:0016324=IEA, GO:0005249=IEA, GO:0016021=IEA} apical plasma membrane, integral to membrane voltage-gated potassium channel activity Human Ensembl:ENSRNOP00000065211 KCNF1 Reactome UniProtKB {GO:0005251=GO_REF:0000033, GO:0005886=Reactome:REACT_75857, GO:0008076=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0005267=PMID:9434767, GO:0051260=GO_REF:0000002, GO:0006813=PMID:9434767} Q9H3M0 Potassium voltage-gated channel subfamily F member 1 protein 20130301 {GO:0005251=IBA, GO:0005886=TAS, GO:0008076=IEA, GO:0007268=TAS, GO:0005267=TAS, GO:0051260=IEA, GO:0006813=TAS} potassium ion transport, protein homooligomerization, synaptic transmission plasma membrane, voltage-gated potassium channel complex delayed rectifier potassium channel activity, potassium channel activity Human KCNG1 HPA UniProtKB {GO:0005251=GO_REF:0000033, GO:0005886=Reactome:REACT_75857, GO:0008076=GO_REF:0000002, GO:0005249=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0005267=PMID:9434767, GO:0051260=GO_REF:0000002, GO:0016021=GO_REF:0000029, GO:0006813=PMID:9434767, GO:0043231=GO_REF:0000052} Q9UIX4 Potassium voltage-gated channel subfamily G member 1 protein 20111111 {GO:0005251=IBA, GO:0005886=TAS, GO:0008076=IEA, GO:0005249=IEA, GO:0007268=TAS, GO:0005267=NAS, GO:0051260=IEA, GO:0016021=NAS, GO:0006813=NAS, GO:0043231=IDA} potassium ion transport, protein homooligomerization, synaptic transmission integral to membrane, intracellular membrane-bounded organelle, plasma membrane, voltage-gated potassium channel complex delayed rectifier potassium channel activity, potassium channel activity, voltage-gated potassium channel activity Human KCNG2 Reactome UniProtKB {GO:0005251=PMID:10551266, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0005886=Reactome:REACT_75857, GO:0008076=GO_REF:0000002, GO:0008016=PMID:10551266, GO:0007268=Reactome:REACT_13685, GO:0051260=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0006813=PMID:10551266} Q9UJ96 Potassium voltage-gated channel subfamily G member 2 protein 20130301 {GO:0005251=TAS, GO:0006112=TAS, GO:0050796=TAS, GO:0005886=TAS, GO:0008076=IEA, GO:0008016=TAS, GO:0007268=TAS, GO:0051260=IEA, GO:0044281=TAS, GO:0006813=TAS} energy reserve metabolic process, potassium ion transport, protein homooligomerization, regulation of heart contraction, regulation of insulin secretion, small molecule metabolic process, synaptic transmission plasma membrane, voltage-gated potassium channel complex delayed rectifier potassium channel activity Human KCNG3 Reactome UniProtKB {GO:0005515=PMID:11852086, GO:0005251=GO_REF:0000033, GO:0005886=Reactome:REACT_75857, GO:0005783=PMID:12060745, GO:0008076=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0051260=GO_REF:0000002} Q8TAE7 Potassium voltage-gated channel subfamily G member 3 protein 20130301 {GO:0005515=IPI, GO:0005251=IBA, GO:0005886=TAS, GO:0005783=IDA, GO:0008076=IEA, GO:0007268=TAS, GO:0051260=IEA} protein homooligomerization, synaptic transmission endoplasmic reticulum, plasma membrane, voltage-gated potassium channel complex delayed rectifier potassium channel activity, protein binding Human KCNG4 Reactome UniProtKB {GO:0005251=GO_REF:0000033, GO:0005886=Reactome:REACT_75857, GO:0008076=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0051260=GO_REF:0000002} Q8TDN1 Potassium voltage-gated channel subfamily G member 4 protein 20130301 {GO:0005251=IBA, GO:0005886=TAS, GO:0008076=IEA, GO:0007268=TAS, GO:0051260=IEA} protein homooligomerization, synaptic transmission plasma membrane, voltage-gated potassium channel complex delayed rectifier potassium channel activity Human KCNH1 IntAct UniProtKB {GO:0005515=PMID:10880439, GO:0005251=PMID:9738473, GO:0005516=GO_REF:0000037, GO:0005886=Reactome:REACT_75857, GO:0008076=PMID:9738473, GO:0007268=Reactome:REACT_13685, GO:0005637=GO_REF:0000039, GO:0007520=PMID:9738473, GO:0006813=PMID:9738473, GO:0000155=GO_REF:0000002} O95259 Potassium voltage-gated channel subfamily H member 1 protein 20130415 {GO:0005515=IPI, GO:0005251=TAS, GO:0005516=IEA, GO:0005886=TAS, GO:0008076=TAS, GO:0007268=TAS, GO:0005637=IEA, GO:0007520=TAS, GO:0006813=TAS, GO:0000155=IEA} myoblast fusion, potassium ion transport, synaptic transmission nuclear inner membrane, plasma membrane, voltage-gated potassium channel complex calmodulin binding, delayed rectifier potassium channel activity, phosphorelay sensor kinase activity, protein binding Human UniProtKB:P62158 KCNH2 BHF-UCL UniProtKB {GO:0005515=PMID:16361248, GO:0005251=PMID:7736582, GO:0005242=GO_REF:0000019, GO:0005886=Reactome:REACT_75857, GO:0008015=PMID:7736582, GO:0008016=PMID:7736582, GO:0007268=Reactome:REACT_13685, GO:0005635=GO_REF:0000019, GO:0060307=GO_REF:0000019, GO:0086091=PMID:7889573, GO:0000155=GO_REF:0000002, GO:0005737=GO_REF:0000019, GO:0006936=PMID:7736582, GO:0008076=PMID:7736582, GO:0005249=PMID:21063088, GO:0016021=GO_REF:0000038, GO:0006813=PMID:7736582, GO:0071805=PMID:21063088} Q12809 Potassium voltage-gated channel subfamily H member 2 protein 20120620 {GO:0005515=IPI, GO:0005251=TAS, GO:0005242=IEA, GO:0005886=TAS, GO:0008015=NAS, GO:0008016=TAS, GO:0007268=TAS, GO:0005635=IEA, GO:0060307=IEA, GO:0086091=IMP, GO:0000155=IEA, GO:0005737=IEA, GO:0006936=TAS, GO:0008076=TAS, GO:0005249=IDA, GO:0016021=IEA, GO:0006813=TAS, GO:0071805=IDA} blood circulation, muscle contraction, potassium ion transmembrane transport, potassium ion transport, regulation of heart contraction, regulation of heart rate by cardiac conduction, regulation of ventricular cardiac muscle cell membrane repolarization, synaptic transmission cytoplasm, integral to membrane, nuclear envelope, plasma membrane, voltage-gated potassium channel complex delayed rectifier potassium channel activity, inward rectifier potassium channel activity, phosphorelay sensor kinase activity, protein binding, voltage-gated potassium channel activity Human KCNH5 Reactome UniProtKB {GO:0005622=PMID:22855790, GO:0005516=GO_REF:0000037, GO:0005886=Reactome:REACT_75857, GO:0009986=PMID:22855790, GO:0010389=PMID:22855790, GO:0005249=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0016021=GO_REF:0000037, GO:0000155=GO_REF:0000002} Q8NCM2 Potassium voltage-gated channel subfamily H member 5 protein 20130301 {GO:0005622=IDA, GO:0005516=IEA, GO:0005886=TAS, GO:0009986=IDA, GO:0010389=IDA, GO:0005249=IEA, GO:0007268=TAS, GO:0016021=IEA, GO:0000155=IEA} regulation of G2/M transition of mitotic cell cycle, synaptic transmission cell surface, integral to membrane, intracellular, plasma membrane calmodulin binding, phosphorelay sensor kinase activity, voltage-gated potassium channel activity Human KCNH8 Reactome UniProtKB {GO:0005886=Reactome:REACT_75857, GO:0016020=GO_REF:0000002, GO:0005249=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0016021=GO_REF:0000037, GO:0000155=GO_REF:0000002} Q96L42 Potassium voltage-gated channel subfamily H member 8 protein 20130301 {GO:0005886=TAS, GO:0016020=IEA, GO:0005249=IEA, GO:0007268=TAS, GO:0016021=IEA, GO:0000155=IEA} synaptic transmission integral to membrane, membrane, plasma membrane phosphorelay sensor kinase activity, voltage-gated potassium channel activity Human KCNIP1 IntAct UniProtKB {GO:0005515=PMID:15358149, GO:0005513=PMID:10676964, GO:0005244=GO_REF:0000037, GO:0046982=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000019, GO:0005267=GO_REF:0000037, GO:0015459=GO_REF:0000019, GO:0007268=PMID:10676964, GO:0030425=GO_REF:0000019, GO:0007165=PMID:10676964, GO:0047485=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0045760=GO_REF:0000019} Q9NZI2 Kv channel-interacting protein 1 protein 20130415 {GO:0005515=IPI, GO:0005513=TAS, GO:0005244=IEA, GO:0046982=IEA, GO:0005886=IEA, GO:0005509=IEA, GO:0005267=IEA, GO:0015459=IEA, GO:0007268=TAS, GO:0030425=IEA, GO:0007165=TAS, GO:0047485=IEA, GO:0043025=IEA, GO:0045760=IEA} detection of calcium ion, positive regulation of action potential, signal transduction, synaptic transmission dendrite, neuronal cell body, plasma membrane calcium ion binding, potassium channel activity, potassium channel regulator activity, protein N-terminus binding, protein binding, protein heterodimerization activity, voltage-gated ion channel activity Human UniProtKB:Q9NS61-3 KCNIP2 PINC UniProtKB {GO:0005250=PMID:11287421, GO:0005513=PMID:10676964, GO:0046923=PMID:11287421, GO:0005509=PMID:11287421, GO:0008016=PMID:11287421, GO:0007268=PMID:11287421, GO:0007165=PMID:10676964, GO:0005737=PMID:11287421, GO:0047485=PMID:11287421, GO:0006936=PMID:11287421, GO:0045163=PMID:11287421, GO:0008076=PMID:11287421, GO:0006813=PMID:11287421} Q9NS61 Kv channel-interacting protein 2 protein 20061106 {GO:0005250=TAS, GO:0005513=TAS, GO:0046923=NAS, GO:0005509=TAS, GO:0008016=TAS, GO:0007268=NAS, GO:0007165=TAS, GO:0005737=IDA, GO:0047485=IPI, GO:0006936=NAS, GO:0045163=IDA, GO:0008076=NAS, GO:0006813=TAS} clustering of voltage-gated potassium channels, detection of calcium ion, muscle contraction, potassium ion transport, regulation of heart contraction, signal transduction, synaptic transmission cytoplasm, voltage-gated potassium channel complex A-type (transient outward) potassium channel activity, ER retention sequence binding, calcium ion binding, protein N-terminus binding Human KCNIP3 PINC UniProtKB {GO:0005794=GO_REF:0000039, GO:0005244=GO_REF:0000037, GO:0006357=PMID:10078534, GO:0005886=GO_REF:0000039, GO:0005783=GO_REF:0000039, GO:0003714=PMID:10078534, GO:0005509=GO_REF:0000002, GO:0005267=GO_REF:0000037, GO:0006915=GO_REF:0000037, GO:0015459=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0000122=GO_REF:0000019, GO:0008022=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0006886=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0019233=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0007165=PMID:10900016, GO:0043523=GO_REF:0000019, GO:0007610=GO_REF:0000019, GO:0048265=GO_REF:0000019, GO:0048306=GO_REF:0000019} Q9Y2W7 Calsenilin protein 20030904 {GO:0005794=IEA, GO:0005244=IEA, GO:0006357=TAS, GO:0005886=IEA, GO:0005783=IEA, GO:0003714=TAS, GO:0005509=IEA, GO:0005267=IEA, GO:0006915=IEA, GO:0015459=IEA, GO:0005634=IEA, GO:0000122=IEA, GO:0008022=IEA, GO:0003677=IEA, GO:0006886=IEA, GO:0006351=IEA, GO:0019233=IEA, GO:0005829=IEA, GO:0007165=TAS, GO:0043523=IEA, GO:0007610=IEA, GO:0048265=IEA, GO:0048306=IEA} apoptotic process, behavior, intracellular protein transport, negative regulation of transcription from RNA polymerase II promoter, regulation of neuron apoptotic process, regulation of transcription from RNA polymerase II promoter, response to pain, sensory perception of pain, signal transduction, transcription, DNA-dependent Golgi apparatus, cytosol, endoplasmic reticulum, nucleus, plasma membrane DNA binding, calcium ion binding, calcium-dependent protein binding, potassium channel activity, potassium channel regulator activity, protein C-terminus binding, transcription corepressor activity, voltage-gated ion channel activity Human KCNIP4 UniProtKB UniProtKB {GO:0005244=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0043025=GO_REF:0000019, GO:0005267=GO_REF:0000037, GO:0030425=GO_REF:0000019} Q6PIL6 Kv channel-interacting protein 4 protein 20130413 {GO:0005244=IEA, GO:0005886=IEA, GO:0005509=IEA, GO:0043025=IEA, GO:0005267=IEA, GO:0030425=IEA} dendrite, neuronal cell body, plasma membrane calcium ion binding, potassium channel activity, voltage-gated ion channel activity Human UniProtKB-SubCell:SL-0039 KCNJ1 Reactome UniProtKB {GO:0005242=GO_REF:0000002, GO:0007588=PMID:9015377, GO:0005886=Reactome:REACT_75810, GO:0001822=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0009791=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0070294=GO_REF:0000019, GO:0001894=GO_REF:0000019, GO:1900128=GO_REF:0000019, GO:0008076=PMID:9015377, GO:0072358=GO_REF:0000019, GO:0006813=PMID:9015377} P48048 ATP-sensitive inward rectifier potassium channel 1 protein 20110522 {GO:0005242=IEA, GO:0007588=TAS, GO:0005886=TAS, GO:0001822=IEA, GO:0007268=TAS, GO:0009791=IEA, GO:0005524=IEA, GO:0070294=IEA, GO:0001894=IEA, GO:1900128=IEA, GO:0008076=TAS, GO:0072358=IEA, GO:0006813=TAS} cardiovascular system development, excretion, kidney development, post-embryonic development, potassium ion transport, regulation of G-protein activated inward rectifier potassium channel activity, renal sodium ion absorption, synaptic transmission, tissue homeostasis plasma membrane, voltage-gated potassium channel complex ATP binding, inward rectifier potassium channel activity Human KCNJ10 Reactome UniProtKB {GO:0005515=PMID:17628813, GO:0021554=GO_REF:0000019, GO:0005886=Reactome:REACT_75810, GO:0022010=GO_REF:0000019, GO:0055075=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0042802=GO_REF:0000019, GO:0016323=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0015272=PMID:8995301, GO:0006954=GO_REF:0000019, GO:0016010=GO_REF:0000019, GO:0051289=GO_REF:0000019, GO:0048169=GO_REF:0000019, GO:0007628=GO_REF:0000019, GO:0006813=PMID:8995301, GO:0009637=GO_REF:0000019, GO:0010107=GO_REF:0000019, GO:0051385=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0060075=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0005902=GO_REF:0000019, GO:0060081=GO_REF:0000019, GO:0005887=PMID:8995301, GO:0051935=GO_REF:0000019, GO:0007601=GO_REF:0000019, GO:0051930=GO_REF:0000019} P78508 ATP-sensitive inward rectifier potassium channel 10 protein 20110522 {GO:0005515=IPI, GO:0021554=IEA, GO:0005886=TAS, GO:0022010=IEA, GO:0055075=IEA, GO:0007268=TAS, GO:0042802=IEA, GO:0016323=IEA, GO:0016324=IEA, GO:0015272=TAS, GO:0006954=IEA, GO:0016010=IEA, GO:0051289=IEA, GO:0048169=IEA, GO:0007628=IEA, GO:0006813=TAS, GO:0009637=IEA, GO:0010107=IEA, GO:0051385=IEA, GO:0051384=IEA, GO:0060075=IEA, GO:0005524=IEA, GO:0005902=IEA, GO:0060081=IEA, GO:0005887=TAS, GO:0051935=IEA, GO:0007601=IEA, GO:0051930=IEA} L-glutamate uptake involved in synaptic transmission, adult walking behavior, central nervous system myelination, inflammatory response, membrane hyperpolarization, optic nerve development, potassium ion homeostasis, potassium ion import, potassium ion transport, protein homotetramerization, regulation of long-term neuronal synaptic plasticity, regulation of resting membrane potential, regulation of sensory perception of pain, response to blue light, response to glucocorticoid stimulus, response to mineralocorticoid stimulus, synaptic transmission, visual perception apical plasma membrane, basolateral plasma membrane, dystrophin-associated glycoprotein complex, integral to plasma membrane, microvillus, plasma membrane ATP binding, ATP-activated inward rectifier potassium channel activity, identical protein binding, protein binding Human KCNJ11 BHF-UCL UniProtKB {GO:0008282=PMID:19805355, GO:0005886=PMID:19805355, GO:0005783=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0005739=GO_REF:0000019, GO:0015272=GO_REF:0000024, GO:0005249=PMID:19805355, GO:0008076=PMID:20610380, GO:0031072=GO_REF:0000019, GO:0042391=PMID:18073297, GO:0006006=PMID:15115830, GO:0033198=PMID:18073297, GO:0046676=PMID:8923010, GO:0071805=PMID:19805355, GO:0042493=PMID:18073297, GO:0030506=PMID:20610380, GO:0030315=GO_REF:0000019, GO:0010107=GO_REF:0000024, GO:0030955=PMID:8923010, GO:0033574=GO_REF:0000019, GO:0008022=GO_REF:0000019, GO:0005524=PMID:12860923, GO:0044325=PMID:20610380, GO:0006112=Reactome:REACT_1505, GO:0050796=PMID:15115830, GO:0005887=PMID:8923010, GO:0050877=PMID:15115830, GO:0016021=GO_REF:0000038} Q14654 ATP-sensitive inward rectifier potassium channel 11 protein 20120615 {GO:0008282=IDA, GO:0005886=IDA, GO:0005783=IEA, GO:0007268=TAS, GO:0044281=TAS, GO:0005739=IEA, GO:0015272=ISS, GO:0005249=IDA, GO:0008076=IDA, GO:0031072=IEA, GO:0042391=IDA, GO:0006006=IMP, GO:0033198=IDA, GO:0046676=IMP, GO:0071805=IDA, GO:0042493=IMP, GO:0030506=IPI, GO:0030315=IEA, GO:0010107=ISS, GO:0030955=TAS, GO:0033574=IEA, GO:0008022=IEA, GO:0005524=ISS, GO:0044325=IPI, GO:0006112=TAS, GO:0050796=IMP, GO:0005887=TAS, GO:0050877=IMP, GO:0016021=IEA} energy reserve metabolic process, glucose metabolic process, negative regulation of insulin secretion, neurological system process, potassium ion import, potassium ion transmembrane transport, regulation of insulin secretion, regulation of membrane potential, response to ATP, response to drug, response to testosterone stimulus, small molecule metabolic process, synaptic transmission ATP-sensitive potassium channel complex, T-tubule, endoplasmic reticulum, integral to membrane, integral to plasma membrane, mitochondrion, plasma membrane, voltage-gated potassium channel complex ATP binding, ATP-activated inward rectifier potassium channel activity, ankyrin binding, heat shock protein binding, ion channel binding, potassium ion binding, protein C-terminus binding, voltage-gated potassium channel activity Human KCNJ12 Reactome UniProtKB {GO:0005242=GO_REF:0000002, GO:0006936=PMID:7859381, GO:0005886=Reactome:REACT_75758, GO:0008015=PMID:7859381, GO:0008016=PMID:7859381, GO:0007268=Reactome:REACT_13685, GO:0015459=PMID:8647284, GO:0016021=GO_REF:0000037, GO:0008200=PMID:8647284, GO:0006813=PMID:7859381} Q14500 ATP-sensitive inward rectifier potassium channel 12 protein 20130301 {GO:0005242=IEA, GO:0006936=TAS, GO:0005886=TAS, GO:0008015=NAS, GO:0008016=TAS, GO:0007268=TAS, GO:0015459=TAS, GO:0016021=IEA, GO:0008200=TAS, GO:0006813=TAS} blood circulation, muscle contraction, potassium ion transport, regulation of heart contraction, synaptic transmission integral to membrane, plasma membrane inward rectifier potassium channel activity, ion channel inhibitor activity, potassium channel regulator activity Human KCNJ15 Reactome UniProtKB {GO:0005242=GO_REF:0000019, GO:0005886=Reactome:REACT_25066, GO:0005887=PMID:8995301, GO:0007268=Reactome:REACT_13685, GO:0016021=GO_REF:0000002, GO:0006813=PMID:8995301} Q99712 ATP-sensitive inward rectifier potassium channel 15 protein 20130301 {GO:0005242=IEA, GO:0005886=TAS, GO:0005887=TAS, GO:0007268=TAS, GO:0016021=IEA, GO:0006813=TAS} potassium ion transport, synaptic transmission integral to membrane, integral to plasma membrane, plasma membrane inward rectifier potassium channel activity Human KCNJ16 Reactome UniProtKB {GO:0005242=PMID:11060447, GO:0005886=Reactome:REACT_75810, GO:0016020=GO_REF:0000002, GO:0008076=PMID:11060447, GO:0007268=Reactome:REACT_13685, GO:0016021=GO_REF:0000038, GO:0006813=PMID:11060447} Q9NPI9 Inward rectifier potassium channel 16 protein 20110522 {GO:0005242=NAS, GO:0005886=TAS, GO:0016020=IEA, GO:0008076=NAS, GO:0007268=TAS, GO:0016021=IEA, GO:0006813=NAS} potassium ion transport, synaptic transmission integral to membrane, membrane, plasma membrane, voltage-gated potassium channel complex inward rectifier potassium channel activity Human KCNJ18 UniProtKB UniProtKB {GO:0005242=PMID:20074522, GO:0005886=PMID:20074522, GO:0016021=GO_REF:0000037} B7U540 Inward rectifier potassium channel 18 protein 20100511 {GO:0005242=IDA, GO:0005886=IDA, GO:0016021=IEA} integral to membrane, plasma membrane inward rectifier potassium channel activity Human KCNJ2 Reactome UniProtKB {GO:0005242=GO_REF:0000002, GO:0015693=GO_REF:0000019, GO:0005886=Reactome:REACT_75758, GO:0005887=PMID:7696590, GO:0043025=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0086001=GO_REF:0000019, GO:0006813=PMID:7696590, GO:0030425=GO_REF:0000019, GO:0042802=GO_REF:0000019} P63252 Inward rectifier potassium channel 2 protein 20130301 {GO:0005242=IEA, GO:0015693=IEA, GO:0005886=TAS, GO:0005887=TAS, GO:0043025=IEA, GO:0007268=TAS, GO:0086001=IEA, GO:0006813=TAS, GO:0030425=IEA, GO:0042802=IEA} magnesium ion transport, potassium ion transport, regulation of cardiac muscle cell action potential, synaptic transmission dendrite, integral to plasma membrane, neuronal cell body, plasma membrane identical protein binding, inward rectifier potassium channel activity Human KCNJ3 BHF-UCL UniProtKB {GO:0005515=PMID:12297500, GO:0005242=PMID:12297500, GO:0005886=Reactome:REACT_25066, GO:0015467=GO_REF:0000002, GO:0008076=PMID:8804710, GO:0051602=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0030315=GO_REF:0000019, GO:0006813=PMID:8804710, GO:0009897=GO_REF:0000019} P48549 G protein-activated inward rectifier potassium channel 1 protein 20080903 {GO:0005515=IPI, GO:0005242=IDA, GO:0005886=TAS, GO:0015467=IEA, GO:0008076=TAS, GO:0051602=IEA, GO:0007268=TAS, GO:0030315=IEA, GO:0006813=TAS, GO:0009897=IEA} potassium ion transport, response to electrical stimulus, synaptic transmission T-tubule, external side of plasma membrane, plasma membrane, voltage-gated potassium channel complex G-protein activated inward rectifier potassium channel activity, inward rectifier potassium channel activity, protein binding Human UniProtKB:P48051 KCNJ4 Reactome UniProtKB {GO:0005515=PMID:16855024, GO:0016323=PMID:16855024, GO:0005242=GO_REF:0000002, GO:0005886=Reactome:REACT_75758, GO:0008076=PMID:8051145, GO:0007268=Reactome:REACT_13685, GO:0030165=PMID:16855024, GO:0006813=PMID:8051145, GO:0030659=GO_REF:0000039} P48050 Inward rectifier potassium channel 4 protein 20130301 {GO:0005515=IPI, GO:0016323=IDA, GO:0005242=IEA, GO:0005886=TAS, GO:0008076=TAS, GO:0007268=TAS, GO:0030165=IPI, GO:0006813=TAS, GO:0030659=IEA} potassium ion transport, synaptic transmission basolateral plasma membrane, cytoplasmic vesicle membrane, plasma membrane, voltage-gated potassium channel complex PDZ domain binding, inward rectifier potassium channel activity, protein binding Human KCNJ5 BHF-UCL UniProtKB {GO:0005515=PMID:12297500, GO:0005242=PMID:12297500, GO:0005886=Reactome:REACT_25066, GO:0015467=PMID:8834003, GO:0008076=PMID:8834003, GO:0007268=Reactome:REACT_13685, GO:0016021=GO_REF:0000002, GO:0006813=PMID:8834003} P48544 G protein-activated inward rectifier potassium channel 4 protein 20080903 {GO:0005515=IPI, GO:0005242=IDA, GO:0005886=TAS, GO:0015467=TAS, GO:0008076=TAS, GO:0007268=TAS, GO:0016021=IEA, GO:0006813=TAS} potassium ion transport, synaptic transmission integral to membrane, plasma membrane, voltage-gated potassium channel complex G-protein activated inward rectifier potassium channel activity, inward rectifier potassium channel activity, protein binding Human UniProtKB:P48051 KCNJ6 BHF-UCL UniProtKB {GO:0005515=PMID:12297500, GO:0005242=PMID:7796919, GO:0005794=PMID:16780588, GO:0005886=Reactome:REACT_25066, GO:0015467=GO_REF:0000019, GO:0008076=PMID:7796919, GO:0007268=Reactome:REACT_13477, GO:0006813=PMID:7796919} P48051 G protein-activated inward rectifier potassium channel 2 protein 20080903 {GO:0005515=IPI, GO:0005242=TAS, GO:0005794=IDA, GO:0005886=TAS, GO:0015467=IEA, GO:0008076=TAS, GO:0007268=TAS, GO:0006813=TAS} potassium ion transport, synaptic transmission Golgi apparatus, plasma membrane, voltage-gated potassium channel complex G-protein activated inward rectifier potassium channel activity, inward rectifier potassium channel activity, protein binding Human UniProtKB:Q92806 KCNJ8 Reactome UniProtKB {GO:0005242=PMID:7890693, GO:0005886=Reactome:REACT_111144, GO:0008282=GO_REF:0000019, GO:0001822=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0010107=GO_REF:0000019, GO:0030016=GO_REF:0000019, GO:0005524=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0007507=GO_REF:0000019, GO:0042383=GO_REF:0000019, GO:0051607=GO_REF:0000019, GO:0015272=GO_REF:0000019, GO:0008076=PMID:7890693, GO:0042311=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0006813=PMID:7890693, GO:0043330=GO_REF:0000019, GO:0009268=GO_REF:0000019} Q15842 ATP-sensitive inward rectifier potassium channel 8 protein 20130301 {GO:0005242=TAS, GO:0005886=TAS, GO:0008282=IEA, GO:0001822=IEA, GO:0007268=TAS, GO:0010107=IEA, GO:0030016=IEA, GO:0005524=IEA, GO:0005739=IEA, GO:0007507=IEA, GO:0042383=IEA, GO:0051607=IEA, GO:0015272=IEA, GO:0008076=TAS, GO:0042311=IEA, GO:0032496=IEA, GO:0006813=TAS, GO:0043330=IEA, GO:0009268=IEA} defense response to virus, heart development, kidney development, potassium ion import, potassium ion transport, response to exogenous dsRNA, response to lipopolysaccharide, response to pH, synaptic transmission, vasodilation ATP-sensitive potassium channel complex, mitochondrion, myofibril, plasma membrane, sarcolemma, voltage-gated potassium channel complex ATP binding, ATP-activated inward rectifier potassium channel activity, inward rectifier potassium channel activity Human KCNJ9 BHF-UCL UniProtKB {GO:0005515=PMID:12297500, GO:0005886=Reactome:REACT_25066, GO:0015467=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0016021=GO_REF:0000037} Q92806 G protein-activated inward rectifier potassium channel 3 protein 20080903 {GO:0005515=IPI, GO:0005886=TAS, GO:0015467=IEA, GO:0007268=TAS, GO:0016021=IEA} synaptic transmission integral to membrane, plasma membrane G-protein activated inward rectifier potassium channel activity, protein binding Human UniProtKB:P48544 KCNK1 InterPro UniProtKB {GO:0005242=PMID:8605869, GO:0016324=GO_REF:0000019, GO:0005886=Reactome:REACT_75806, GO:0008076=PMID:8605869, GO:0005267=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0016021=GO_REF:0000002, GO:0031526=GO_REF:0000019, GO:0006813=PMID:8605869, GO:0035094=GO_REF:0000019, GO:0005768=GO_REF:0000019} Q5T5E7 Potassium channel subfamily K member 1 protein 20130413 {GO:0005242=TAS, GO:0016324=IEA, GO:0005886=TAS, GO:0008076=TAS, GO:0005267=IEA, GO:0007268=TAS, GO:0016021=IEA, GO:0031526=IEA, GO:0006813=TAS, GO:0035094=IEA, GO:0005768=IEA} potassium ion transport, response to nicotine, synaptic transmission apical plasma membrane, brush border membrane, endosome, integral to membrane, plasma membrane, voltage-gated potassium channel complex inward rectifier potassium channel activity, potassium channel activity Human InterPro:IPR005408 KCNK10 Reactome UniProtKB {GO:0007165=PMID:10880510, GO:0005244=GO_REF:0000037, GO:0005886=Reactome:REACT_75846, GO:0016020=GO_REF:0000002, GO:0006810=PMID:10880510, GO:0007268=Reactome:REACT_13685, GO:0005267=GO_REF:0000019, GO:0016021=GO_REF:0000037} P57789 Potassium channel subfamily K member 10 protein 20130301 {GO:0007165=NAS, GO:0005244=IEA, GO:0005886=TAS, GO:0016020=IEA, GO:0006810=TAS, GO:0007268=TAS, GO:0005267=IEA, GO:0016021=IEA} signal transduction, synaptic transmission, transport integral to membrane, membrane, plasma membrane potassium channel activity, voltage-gated ion channel activity Human KCNK15 UniProtKB UniProtKB {GO:0005244=PMID:11749039, GO:0005267=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q9H427 Potassium channel subfamily K member 15 protein 20050811 {GO:0005244=IDA, GO:0005267=IEA, GO:0016021=IEA} integral to membrane potassium channel activity, voltage-gated ion channel activity NOT Human KCNK17 Reactome UniProtKB {GO:0005244=GO_REF:0000037, GO:0005886=Reactome:REACT_75749, GO:0016020=GO_REF:0000029, GO:0007268=Reactome:REACT_13685, GO:0005267=PMID:11248242, GO:0016021=GO_REF:0000037, GO:0006813=PMID:11248242} Q96T54 Potassium channel subfamily K member 17 protein 20110522 {GO:0005244=IEA, GO:0005886=TAS, GO:0016020=NAS, GO:0007268=TAS, GO:0005267=IDA, GO:0016021=IEA, GO:0006813=IDA} potassium ion transport, synaptic transmission integral to membrane, membrane, plasma membrane potassium channel activity, voltage-gated ion channel activity Human KCNK18 BHF-UCL UniProtKB {GO:0071435=PMID:12754259, GO:0015271=PMID:12754259, GO:0005886=Reactome:REACT_75865, GO:0005887=PMID:12754259, GO:0007268=Reactome:REACT_13685, GO:0005267=Reactome:REACT_75865, GO:0006813=PMID:20006580, GO:0015269=GO_REF:0000019, GO:0071467=PMID:12754259} Q7Z418 Potassium channel subfamily K member 18 protein 20111118 {GO:0071435=IDA, GO:0015271=IDA, GO:0005886=TAS, GO:0005887=IC, GO:0007268=TAS, GO:0005267=TAS, GO:0006813=IDA, GO:0015269=IEA, GO:0071467=IDA} cellular response to pH, potassium ion export, potassium ion transport, synaptic transmission integral to plasma membrane, plasma membrane calcium-activated potassium channel activity, outward rectifier potassium channel activity, potassium channel activity Human GO:0015271 KCNK3 Reactome UniProtKB {GO:0071294=GO_REF:0000019, GO:0005886=Reactome:REACT_75935, GO:0046982=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0051481=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0071456=GO_REF:0000019, GO:0005267=PMID:9312005, GO:0008022=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0005252=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0005887=PMID:9312005, GO:0090102=GO_REF:0000019, GO:0006813=PMID:9312005} O14649 Potassium channel subfamily K member 3 protein 20110522 {GO:0071294=IEA, GO:0005886=TAS, GO:0046982=IEA, GO:0042493=IEA, GO:0051481=IEA, GO:0007268=TAS, GO:0071456=IEA, GO:0005267=TAS, GO:0008022=IEA, GO:0042803=IEA, GO:0005252=IEA, GO:0007420=IEA, GO:0005887=TAS, GO:0090102=IEA, GO:0006813=TAS} brain development, cellular response to hypoxia, cellular response to zinc ion, cochlea development, potassium ion transport, reduction of cytosolic calcium ion concentration, response to drug, synaptic transmission integral to plasma membrane, plasma membrane open rectifier potassium channel activity, potassium channel activity, protein C-terminus binding, protein heterodimerization activity, protein homodimerization activity Human KCNK4 Reactome UniProtKB {GO:0005244=GO_REF:0000037, GO:0005886=Reactome:REACT_75846, GO:0016020=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0005267=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0006813=PMID:10767409} Q9NYG8 Potassium channel subfamily K member 4 protein 20130301 {GO:0005244=IEA, GO:0005886=TAS, GO:0016020=IEA, GO:0007268=TAS, GO:0005267=IEA, GO:0016021=IEA, GO:0006813=TAS} potassium ion transport, synaptic transmission integral to membrane, membrane, plasma membrane potassium channel activity, voltage-gated ion channel activity Human KCNK5 PINC UniProtKB {GO:0007588=PMID:9812978, GO:0005244=GO_REF:0000037, GO:0005887=PMID:9812978, GO:0005267=GO_REF:0000037, GO:0006813=PMID:9812978} O95279 Potassium channel subfamily K member 5 protein 20030904 {GO:0007588=TAS, GO:0005244=IEA, GO:0005887=TAS, GO:0005267=IEA, GO:0006813=TAS} excretion, potassium ion transport integral to plasma membrane potassium channel activity, voltage-gated ion channel activity Human KCNK9 Reactome UniProtKB {GO:0005244=GO_REF:0000037, GO:0005886=Reactome:REACT_75935, GO:0016020=GO_REF:0000029, GO:0046982=GO_REF:0000019, GO:0090102=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0005267=GO_REF:0000029, GO:0016021=GO_REF:0000037, GO:0006813=PMID:11042359, GO:0042803=GO_REF:0000019, GO:0008021=GO_REF:0000019} Q9NPC2 Potassium channel subfamily K member 9 protein 20110522 {GO:0005244=IEA, GO:0005886=TAS, GO:0016020=NAS, GO:0046982=IEA, GO:0090102=IEA, GO:0007268=TAS, GO:0005267=NAS, GO:0016021=IEA, GO:0006813=NAS, GO:0042803=IEA, GO:0008021=IEA} cochlea development, potassium ion transport, synaptic transmission integral to membrane, membrane, plasma membrane, synaptic vesicle potassium channel activity, protein heterodimerization activity, protein homodimerization activity, voltage-gated ion channel activity Human KCNMA1 InterPro UniProtKB {GO:0005515=PMID:15703204, GO:0045475=GO_REF:0000019, GO:0005886=Reactome:REACT_75757, GO:0005783=GO_REF:0000019, GO:0007605=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0019228=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0060087=GO_REF:0000019, GO:0016324=PMID:10840032, GO:0043195=GO_REF:0000019, GO:0008076=GO_REF:0000002, GO:0005249=GO_REF:0000002, GO:0045211=GO_REF:0000019, GO:0042391=PMID:7993625, GO:0007628=GO_REF:0000019, GO:0050885=GO_REF:0000019, GO:0048469=GO_REF:0000019, GO:0051260=GO_REF:0000019, GO:0006813=PMID:11245614, GO:0034465=PMID:18180950, GO:0071805=GO_REF:0000033, GO:0060072=GO_REF:0000002, GO:0046541=GO_REF:0000019, GO:0001666=PMID:15528406, GO:0043065=PMID:11245614, GO:0030007=PMID:11245614, GO:0042491=GO_REF:0000019, GO:0003779=PMID:15703204, GO:0006970=PMID:10840032, GO:0060073=PMID:11641143, GO:0060083=PMID:11641143, GO:0045794=PMID:12388065, GO:0051592=PMID:18458941, GO:0060082=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0005901=PMID:15703204, GO:0016021=PMID:7877450, GO:0032344=GO_REF:0000019, GO:0015269=PMID:11245614, GO:0009897=GO_REF:0000019} Q5SVK5 Calcium-activated potassium channel subunit alpha-1 protein 20130413 {GO:0005515=IPI, GO:0045475=IEA, GO:0005886=TAS, GO:0005783=IEA, GO:0007605=IEA, GO:0007268=TAS, GO:0019228=IEA, GO:0046872=IEA, GO:0060087=IEA, GO:0016324=IDA, GO:0043195=IEA, GO:0008076=IEA, GO:0005249=IEA, GO:0045211=IEA, GO:0042391=IDA, GO:0007628=IEA, GO:0050885=IEA, GO:0048469=IEA, GO:0051260=IEA, GO:0006813=IDA, GO:0034465=IMP, GO:0071805=IBA, GO:0060072=IEA, GO:0046541=IEA, GO:0001666=IDA, GO:0043065=IMP, GO:0030007=IDA, GO:0042491=IEA, GO:0003779=IDA, GO:0006970=IDA, GO:0060073=IDA, GO:0060083=IDA, GO:0045794=IDA, GO:0051592=IDA, GO:0060082=IEA, GO:0016020=IEA, GO:0007596=TAS, GO:0005901=IDA, GO:0016021=IDA, GO:0032344=IEA, GO:0015269=IDA, GO:0009897=IEA} adult walking behavior, auditory receptor cell differentiation, blood coagulation, cell maturation, cellular potassium ion homeostasis, eye blink reflex, locomotor rhythm, micturition, negative regulation of cell volume, neuromuscular process controlling balance, positive regulation of apoptotic process, potassium ion transmembrane transport, potassium ion transport, protein homooligomerization, regulation of action potential in neuron, regulation of aldosterone metabolic process, regulation of membrane potential, relaxation of vascular smooth muscle, response to calcium ion, response to carbon monoxide, response to hypoxia, response to osmotic stress, saliva secretion, sensory perception of sound, smooth muscle contraction involved in micturition, synaptic transmission apical plasma membrane, caveola, endoplasmic reticulum, external side of plasma membrane, integral to membrane, membrane, plasma membrane, postsynaptic membrane, terminal bouton, voltage-gated potassium channel complex actin binding, calcium-activated potassium channel activity, large conductance calcium-activated potassium channel activity, metal ion binding, protein binding, voltage-gated potassium channel activity Human InterPro:IPR024939 KCNMB1 Reactome UniProtKB {GO:0051592=GO_REF:0000019, GO:0005886=Reactome:REACT_75757, GO:0007596=Reactome:REACT_604, GO:0008076=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0015459=GO_REF:0000019, GO:0006813=PMID:8799178, GO:0015269=GO_REF:0000019} Q16558 Calcium-activated potassium channel subunit beta-1 protein 20130301 {GO:0051592=IEA, GO:0005886=TAS, GO:0007596=TAS, GO:0008076=IEA, GO:0007268=TAS, GO:0015459=IEA, GO:0006813=TAS, GO:0015269=IEA} blood coagulation, potassium ion transport, response to calcium ion, synaptic transmission plasma membrane, voltage-gated potassium channel complex calcium-activated potassium channel activity, potassium channel regulator activity Human KCNMB2 Reactome UniProtKB {GO:0005513=PMID:10692449, GO:0005886=Reactome:REACT_75757, GO:0015459=PMID:10097176, GO:0007268=Reactome:REACT_13685, GO:0019228=PMID:10692449, GO:0019229=PMID:10692449, GO:0016020=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:10692449, GO:0008076=PMID:10692449, GO:0001508=PMID:10692449, GO:0008200=PMID:10097176, GO:0015269=PMID:10692449, GO:0006813=PMID:10692449} Q9Y691 Calcium-activated potassium channel subunit beta-2 protein 20130301 {GO:0005513=IDA, GO:0005886=TAS, GO:0015459=TAS, GO:0007268=TAS, GO:0019228=IDA, GO:0019229=TAS, GO:0016020=IEA, GO:0007596=TAS, GO:0005887=IDA, GO:0008076=IDA, GO:0001508=IDA, GO:0008200=TAS, GO:0015269=IDA, GO:0006813=IDA} blood coagulation, detection of calcium ion, potassium ion transport, regulation of action potential, regulation of action potential in neuron, regulation of vasoconstriction, synaptic transmission integral to plasma membrane, membrane, plasma membrane, voltage-gated potassium channel complex calcium-activated potassium channel activity, ion channel inhibitor activity, potassium channel regulator activity Human KCNN1 Reactome UniProtKB {GO:0005516=GO_REF:0000037, GO:0005886=Reactome:REACT_75830, GO:0008076=PMID:8781233, GO:0007268=Reactome:REACT_13685, GO:0015269=PMID:8781233, GO:0006813=PMID:8781233, GO:0016286=GO_REF:0000002} Q92952 Small conductance calcium-activated potassium channel protein 1 protein 20130301 {GO:0005516=IEA, GO:0005886=TAS, GO:0008076=TAS, GO:0007268=TAS, GO:0015269=TAS, GO:0006813=TAS, GO:0016286=IEA} potassium ion transport, synaptic transmission plasma membrane, voltage-gated potassium channel complex calcium-activated potassium channel activity, calmodulin binding, small conductance calcium-activated potassium channel activity Human KCNN2 BHF-UCL UniProtKB {GO:0005516=GO_REF:0000037, GO:0030018=GO_REF:0000019, GO:0005886=Reactome:REACT_75830, GO:1901379=PMID:17110593, GO:0007268=Reactome:REACT_13685, GO:0030315=GO_REF:0000019, GO:0016021=PMID:10991935, GO:0015269=PMID:17110593, GO:0006813=PMID:10991935, GO:0071805=PMID:17110593, GO:0016286=PMID:10991935} Q9H2S1 Small conductance calcium-activated potassium channel protein 2 protein 20120928 {GO:0005516=IEA, GO:0030018=IEA, GO:0005886=TAS, GO:1901379=IDA, GO:0007268=TAS, GO:0030315=IEA, GO:0016021=NAS, GO:0015269=IDA, GO:0006813=NAS, GO:0071805=IDA, GO:0016286=TAS} potassium ion transmembrane transport, potassium ion transport, regulation of potassium ion transmembrane transport, synaptic transmission T-tubule, Z disc, integral to membrane, plasma membrane calcium-activated potassium channel activity, calmodulin binding, small conductance calcium-activated potassium channel activity Human KCNN3 Reactome UniProtKB {GO:0005516=GO_REF:0000037, GO:0005737=GO_REF:0000019, GO:0005886=Reactome:REACT_75830, GO:0007268=Reactome:REACT_13685, GO:0016021=GO_REF:0000037, GO:0016286=GO_REF:0000002} Q9UGI6 Small conductance calcium-activated potassium channel protein 3 protein 20130301 {GO:0005516=IEA, GO:0005737=IEA, GO:0005886=TAS, GO:0007268=TAS, GO:0016021=IEA, GO:0016286=IEA} synaptic transmission cytoplasm, integral to membrane, plasma membrane calmodulin binding, small conductance calcium-activated potassium channel activity Human KCNN4 BHF-UCL UniProtKB {GO:0005515=PMID:12198491, GO:0005516=GO_REF:0000037, GO:0005886=Reactome:REACT_75793, GO:0019903=PMID:18796614, GO:0030322=PMID:18796614, GO:0050714=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0006952=PMID:9407042, GO:0050862=PMID:18796614, GO:0045332=GO_REF:0000019, GO:0016286=GO_REF:0000002, GO:0006884=GO_REF:0000019, GO:0008076=PMID:18796614, GO:0006816=PMID:18796614, GO:0016021=GO_REF:0000002, GO:0015269=PMID:18796614, GO:0006813=PMID:9380751, GO:0046541=GO_REF:0000019} O15554 Intermediate conductance calcium-activated potassium channel protein 4 protein 20110805 {GO:0005515=IPI, GO:0005516=IEA, GO:0005886=TAS, GO:0019903=IPI, GO:0030322=IDA, GO:0050714=IEA, GO:0007268=TAS, GO:0006952=TAS, GO:0050862=IDA, GO:0045332=IEA, GO:0016286=IEA, GO:0006884=IEA, GO:0008076=IC, GO:0006816=IDA, GO:0016021=IEA, GO:0015269=IDA, GO:0006813=TAS, GO:0046541=IEA} calcium ion transport, cell volume homeostasis, defense response, phospholipid translocation, positive regulation of T cell receptor signaling pathway, positive regulation of protein secretion, potassium ion transport, saliva secretion, stabilization of membrane potential, synaptic transmission integral to membrane, plasma membrane, voltage-gated potassium channel complex calcium-activated potassium channel activity, calmodulin binding, protein binding, protein phosphatase binding, small conductance calcium-activated potassium channel activity Human GO:0015269 KCNQ1 BHF-UCL UniProtKB {GO:0005251=PMID:8900283, GO:0005516=GO_REF:0000037, GO:0005886=Reactome:REACT_75857, GO:0005770=PMID:21957902, GO:0008015=PMID:8528244, GO:0007605=PMID:9020846, GO:0008016=PMID:8900283, GO:0060306=PMID:8528244, GO:0007268=Reactome:REACT_13685, GO:0016458=GO_REF:0000019, GO:0005764=PMID:21957902, GO:0042221=GO_REF:0000019, GO:0042383=GO_REF:0000019, GO:0016323=PMID:21957902, GO:0071435=PMID:17289006, GO:0015271=GO_REF:0000019, GO:0042589=GO_REF:0000019, GO:0006936=PMID:8528244, GO:0005249=PMID:17289006, GO:0008076=PMID:17289006, GO:0006349=GO_REF:0000019, GO:0072358=GO_REF:0000019, GO:0046676=GO_REF:0000019, GO:0005769=PMID:21957902} P51787 Potassium voltage-gated channel subfamily KQT member 1 protein 20120801 {GO:0005251=IDA, GO:0005516=IEA, GO:0005886=TAS, GO:0005770=IDA, GO:0008015=NAS, GO:0007605=TAS, GO:0008016=IC, GO:0060306=IMP, GO:0007268=TAS, GO:0016458=IEA, GO:0005764=IDA, GO:0042221=IEA, GO:0042383=IEA, GO:0016323=IDA, GO:0071435=IDA, GO:0015271=IEA, GO:0042589=IEA, GO:0006936=TAS, GO:0005249=IDA, GO:0008076=IDA, GO:0006349=IEA, GO:0072358=IEA, GO:0046676=IEA, GO:0005769=IDA} blood circulation, cardiovascular system development, gene silencing, muscle contraction, negative regulation of insulin secretion, potassium ion export, regulation of gene expression by genetic imprinting, regulation of heart contraction, regulation of membrane repolarization, response to chemical stimulus, sensory perception of sound, synaptic transmission basolateral plasma membrane, early endosome, late endosome, lysosome, plasma membrane, sarcolemma, voltage-gated potassium channel complex, zymogen granule membrane calmodulin binding, delayed rectifier potassium channel activity, outward rectifier potassium channel activity, voltage-gated potassium channel activity Human KCNQ2 InterPro UniProtKB {GO:0005251=GO_REF:0000033, GO:0043194=PMID:16525039, GO:0033268=PMID:16525039, GO:0005886=PMID:16525039, GO:0007411=Reactome:REACT_18266, GO:0008076=GO_REF:0000002, GO:0005249=GO_REF:0000002, GO:0030506=PMID:16525039, GO:0007268=Reactome:REACT_13685, GO:0005267=PMID:9430594, GO:0006813=PMID:9677360, GO:0007399=PMID:9425895} Q4VXP7 Potassium voltage-gated channel subfamily KQT member 2 protein 20130413 {GO:0005251=IBA, GO:0043194=ISS, GO:0033268=ISS, GO:0005886=ISS, GO:0007411=TAS, GO:0008076=IEA, GO:0005249=IEA, GO:0030506=IPI, GO:0007268=TAS, GO:0005267=TAS, GO:0006813=TAS, GO:0007399=TAS} axon guidance, nervous system development, potassium ion transport, synaptic transmission axon initial segment, node of Ranvier, plasma membrane, voltage-gated potassium channel complex ankyrin binding, delayed rectifier potassium channel activity, potassium channel activity, voltage-gated potassium channel activity Human InterPro:IPR003091 KCNQ3 BHF-UCL UniProtKB {GO:0005251=GO_REF:0000033, GO:0043194=PMID:16525039, GO:0060081=GO_REF:0000019, GO:0033268=PMID:16525039, GO:0005886=PMID:16525039, GO:0007411=Reactome:REACT_18266, GO:0008076=GO_REF:0000002, GO:0005249=PMID:9677360, GO:0007268=Reactome:REACT_13685, GO:0005267=PMID:9836639, GO:0006813=PMID:9677360} O43525 Potassium voltage-gated channel subfamily KQT member 3 protein 20120607 {GO:0005251=IBA, GO:0043194=ISS, GO:0060081=IEA, GO:0033268=ISS, GO:0005886=ISS, GO:0007411=TAS, GO:0008076=IEA, GO:0005249=TAS, GO:0007268=TAS, GO:0005267=TAS, GO:0006813=TAS} axon guidance, membrane hyperpolarization, potassium ion transport, synaptic transmission axon initial segment, node of Ranvier, plasma membrane, voltage-gated potassium channel complex delayed rectifier potassium channel activity, potassium channel activity, voltage-gated potassium channel activity Human UniProtKB:Q8K3F6 KCNQ4 Reactome UniProtKB {GO:0005251=GO_REF:0000033, GO:0009925=GO_REF:0000039, GO:0042472=GO_REF:0000019, GO:0005886=Reactome:REACT_75857, GO:0007605=GO_REF:0000019, GO:0008076=GO_REF:0000002, GO:0005249=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0005267=PMID:10025409, GO:0006813=PMID:10025409} P56696 Potassium voltage-gated channel subfamily KQT member 4 protein 20130301 {GO:0005251=IBA, GO:0009925=IEA, GO:0042472=IEA, GO:0005886=TAS, GO:0007605=IEA, GO:0008076=IEA, GO:0005249=IEA, GO:0007268=TAS, GO:0005267=TAS, GO:0006813=TAS} inner ear morphogenesis, potassium ion transport, sensory perception of sound, synaptic transmission basal plasma membrane, plasma membrane, voltage-gated potassium channel complex delayed rectifier potassium channel activity, potassium channel activity, voltage-gated potassium channel activity Human KCNQ5 Reactome UniProtKB {GO:0005251=GO_REF:0000033, GO:0005242=PMID:10787416, GO:0006461=PMID:10787416, GO:0005886=Reactome:REACT_75857, GO:0016020=GO_REF:0000002, GO:0005249=GO_REF:0000002, GO:0008076=GO_REF:0000002, GO:0007268=Reactome:REACT_13685} Q9NR82 Potassium voltage-gated channel subfamily KQT member 5 protein 20130301 {GO:0005251=IBA, GO:0005242=TAS, GO:0006461=NAS, GO:0005886=TAS, GO:0016020=IEA, GO:0005249=IEA, GO:0008076=IEA, GO:0007268=TAS} protein complex assembly, synaptic transmission membrane, plasma membrane, voltage-gated potassium channel complex delayed rectifier potassium channel activity, inward rectifier potassium channel activity, voltage-gated potassium channel activity Human KCNRG IntAct UniProtKB {GO:0005783=GO_REF:0000039, GO:0051260=GO_REF:0000002, GO:0042802=PMID:19447967} Q8N5I3 Potassium channel regulatory protein protein 20130415 {GO:0005783=IEA, GO:0051260=IEA, GO:0042802=IPI} protein homooligomerization endoplasmic reticulum identical protein binding Human UniProtKB:Q8N5I3 KCNS3 HPA UniProtKB {GO:0005251=PMID:10484328, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0015459=PMID:10484328, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0043231=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0005249=GO_REF:0000002, GO:0008076=GO_REF:0000002, GO:0051260=GO_REF:0000002, GO:0006813=PMID:10484328} Q9BQ31 Potassium voltage-gated channel subfamily S member 3 protein 20100326 {GO:0005251=TAS, GO:0005794=IDA, GO:0005886=IDA, GO:0015459=TAS, GO:0007268=TAS, GO:0044281=TAS, GO:0043231=IDA, GO:0005737=IDA, GO:0006112=TAS, GO:0050796=TAS, GO:0005249=IEA, GO:0008076=IEA, GO:0051260=IEA, GO:0006813=TAS} energy reserve metabolic process, potassium ion transport, protein homooligomerization, regulation of insulin secretion, small molecule metabolic process, synaptic transmission Golgi apparatus, cytoplasm, intracellular membrane-bounded organelle, plasma membrane, voltage-gated potassium channel complex delayed rectifier potassium channel activity, potassium channel regulator activity, voltage-gated potassium channel activity Human KCNV1 Reactome UniProtKB {GO:0005251=GO_REF:0000033, GO:0005886=Reactome:REACT_75857, GO:0005887=PMID:8670833, GO:0008076=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0015459=PMID:8670833, GO:0051260=GO_REF:0000002, GO:0008200=PMID:8670833, GO:0006813=PMID:8670833} Q6PIU1 Potassium voltage-gated channel subfamily V member 1 protein 20130301 {GO:0005251=IBA, GO:0005886=TAS, GO:0005887=TAS, GO:0008076=IEA, GO:0007268=TAS, GO:0015459=TAS, GO:0051260=IEA, GO:0008200=TAS, GO:0006813=TAS} potassium ion transport, protein homooligomerization, synaptic transmission integral to plasma membrane, plasma membrane, voltage-gated potassium channel complex delayed rectifier potassium channel activity, ion channel inhibitor activity, potassium channel regulator activity Human KCNV2 Reactome UniProtKB {GO:0005251=GO_REF:0000033, GO:0005886=Reactome:REACT_75857, GO:0008076=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0051260=GO_REF:0000002} Q8TDN2 Potassium voltage-gated channel subfamily V member 2 protein 20130301 {GO:0005251=IBA, GO:0005886=TAS, GO:0008076=IEA, GO:0007268=TAS, GO:0051260=IEA} protein homooligomerization, synaptic transmission plasma membrane, voltage-gated potassium channel complex delayed rectifier potassium channel activity Human KCTD1 UniProtKB UniProtKB {GO:0003714=PMID:19115315, GO:0005634=PMID:19115315, GO:0051260=GO_REF:0000002, GO:0045892=PMID:19115315, GO:0006351=GO_REF:0000037, GO:0008134=PMID:19115315} Q719H9 BTB/POZ domain-containing protein KCTD1 protein 20110426 {GO:0003714=IDA, GO:0005634=IDA, GO:0051260=IEA, GO:0045892=IDA, GO:0006351=IEA, GO:0008134=IPI} negative regulation of transcription, DNA-dependent, protein homooligomerization, transcription, DNA-dependent nucleus transcription corepressor activity, transcription factor binding Human KCTD10 HPA UniProtKB {GO:0004842=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0016567=GO_REF:0000024, GO:0031463=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0043161=GO_REF:0000024, GO:0051260=GO_REF:0000002, GO:0005634=GO_REF:0000052} Q9H3F6 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 protein 20090616 {GO:0004842=ISS, GO:0005737=IDA, GO:0016567=ISS, GO:0031463=ISS, GO:0005730=IDA, GO:0043161=ISS, GO:0051260=IEA, GO:0005634=IDA} proteasomal ubiquitin-dependent protein catabolic process, protein homooligomerization, protein ubiquitination Cul3-RING ubiquitin ligase complex, cytoplasm, nucleolus, nucleus ubiquitin-protein ligase activity Human KCTD11 UniPathway UniProtKB {GO:0005737=GO_REF:0000019, GO:0007049=GO_REF:0000037, GO:0016567=GO_REF:0000041, GO:0045666=GO_REF:0000019, GO:0045879=GO_REF:0000019, GO:0051260=GO_REF:0000002, GO:0007406=GO_REF:0000019, GO:0040008=GO_REF:0000037} Q693B1 BTB/POZ domain-containing protein KCTD11 protein 20130413 {GO:0005737=IEA, GO:0007049=IEA, GO:0016567=IEA, GO:0045666=IEA, GO:0045879=IEA, GO:0051260=IEA, GO:0007406=IEA, GO:0040008=IEA} cell cycle, negative regulation of neuroblast proliferation, negative regulation of smoothened signaling pathway, positive regulation of neuron differentiation, protein homooligomerization, protein ubiquitination, regulation of growth cytoplasm Human UniPathway:UPA00143 KCTD12 UniProtKB UniProtKB {GO:0043235=GO_REF:0000019, GO:0042734=GO_REF:0000039, GO:0008277=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000037, GO:0045211=GO_REF:0000039, GO:0051260=GO_REF:0000002} Q96CX2 BTB/POZ domain-containing protein KCTD12 protein 20130413 {GO:0043235=IEA, GO:0042734=IEA, GO:0008277=IEA, GO:0030054=IEA, GO:0005886=IEA, GO:0045211=IEA, GO:0051260=IEA} protein homooligomerization, regulation of G-protein coupled receptor protein signaling pathway cell junction, plasma membrane, postsynaptic membrane, presynaptic membrane, receptor complex Human UniProtKB-SubCell:SL-0219 KCTD13 HPA UniProtKB {GO:0004842=PMID:19782033, GO:0016567=PMID:19782033, GO:0035024=PMID:19782033, GO:0019904=GO_REF:0000019, GO:0045740=GO_REF:0000019, GO:0043149=PMID:19782033, GO:0005634=GO_REF:0000052, GO:0042802=GO_REF:0000019, GO:0006260=PMID:15726626, GO:0016477=PMID:19782033, GO:0031463=PMID:19782033, GO:0051260=GO_REF:0000002, GO:0043161=PMID:19782033, GO:0017049=PMID:19782033} Q8WZ19 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 protein 20111111 {GO:0004842=IDA, GO:0016567=IDA, GO:0035024=IMP, GO:0019904=IEA, GO:0045740=IEA, GO:0043149=IMP, GO:0005634=IDA, GO:0042802=IEA, GO:0006260=ISS, GO:0016477=IMP, GO:0031463=IDA, GO:0051260=IEA, GO:0043161=IDA, GO:0017049=IDA} DNA replication, cell migration, negative regulation of Rho protein signal transduction, positive regulation of DNA replication, proteasomal ubiquitin-dependent protein catabolic process, protein homooligomerization, protein ubiquitination, stress fiber assembly Cul3-RING ubiquitin ligase complex, nucleus GTP-Rho binding, identical protein binding, protein domain specific binding, ubiquitin-protein ligase activity Human KCTD14 InterPro UniProtKB {GO:0051260=GO_REF:0000002} Q9BQ13 BTB/POZ domain-containing protein KCTD14 protein 20130413 {GO:0051260=IEA} protein homooligomerization Human InterPro:IPR003131 KCTD15 InterPro UniProtKB {GO:0051260=GO_REF:0000002} Q96SI1 BTB/POZ domain-containing protein KCTD15 protein 20130413 {GO:0051260=IEA} protein homooligomerization Human InterPro:IPR003131 KCTD16 UniProtKB UniProtKB {GO:0043235=GO_REF:0000019, GO:0042734=GO_REF:0000039, GO:0008277=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000037, GO:0045211=GO_REF:0000039, GO:0051260=GO_REF:0000002} Q68DU8 BTB/POZ domain-containing protein KCTD16 protein 20130413 {GO:0043235=IEA, GO:0042734=IEA, GO:0008277=IEA, GO:0030054=IEA, GO:0005886=IEA, GO:0045211=IEA, GO:0051260=IEA} protein homooligomerization, regulation of G-protein coupled receptor protein signaling pathway cell junction, plasma membrane, postsynaptic membrane, presynaptic membrane, receptor complex Human UniProtKB-SubCell:SL-0219 KCTD17 IntAct UniProtKB {GO:0051260=GO_REF:0000002, GO:0042802=PMID:16189514} Q8N5Z5 BTB/POZ domain-containing protein KCTD17 protein 20130415 {GO:0051260=IEA, GO:0042802=IPI} protein homooligomerization identical protein binding Human UniProtKB:Q8N5Z5 KCTD18 InterPro UniProtKB {GO:0051260=GO_REF:0000002} Q6PI47 BTB/POZ domain-containing protein KCTD18 protein 20130413 {GO:0051260=IEA} protein homooligomerization Human InterPro:IPR003131 KCTD2 InterPro UniProtKB {GO:0051260=GO_REF:0000002} Q14681 BTB/POZ domain-containing protein KCTD2 protein 20130413 {GO:0051260=IEA} protein homooligomerization Human InterPro:IPR003131 KCTD20 InterPro UniProtKB {GO:0051260=GO_REF:0000002} Q7Z5Y7 BTB/POZ domain-containing protein KCTD20 protein 20130413 {GO:0051260=IEA} protein homooligomerization Human InterPro:IPR003131 KCTD21 InterPro UniProtKB {GO:0051260=GO_REF:0000002} Q4G0X4 BTB/POZ domain-containing protein KCTD21 protein 20130413 {GO:0051260=IEA} protein homooligomerization Human InterPro:IPR003131 KCTD3 InterPro UniProtKB {GO:0051260=GO_REF:0000002} Q9Y597 BTB/POZ domain-containing protein KCTD3 protein 20130413 {GO:0051260=IEA} protein homooligomerization Human InterPro:IPR003131 KCTD4 InterPro UniProtKB {GO:0051260=GO_REF:0000002} Q8WVF5 BTB/POZ domain-containing protein KCTD4 protein 20130413 {GO:0051260=IEA} protein homooligomerization Human InterPro:IPR003131 KCTD5 UniProtKB UniProtKB {GO:0005515=PMID:18573101, GO:0019048=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0051260=GO_REF:0000002, GO:0005829=PMID:18573101} Q9NXV2 BTB/POZ domain-containing protein KCTD5 protein 20091102 {GO:0005515=IPI, GO:0019048=IEA, GO:0005634=IEA, GO:0051260=IEA, GO:0005829=IDA} protein homooligomerization, virus-host interaction cytosol, nucleus protein binding Human KCTD6 InterPro UniProtKB {GO:0051260=GO_REF:0000002} Q8NC69 BTB/POZ domain-containing protein KCTD6 protein 20130413 {GO:0051260=IEA} protein homooligomerization Human InterPro:IPR003131 KCTD7 UniProtKB UniProtKB {GO:0008219=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0051260=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000002, GO:0005829=GO_REF:0000039} Q96MP8 BTB/POZ domain-containing protein KCTD7 protein 20130413 {GO:0008219=IEA, GO:0005886=IEA, GO:0051260=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0005829=IEA} cell death, protein homooligomerization cytosol, plasma membrane DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0039 KCTD8 UniProtKB UniProtKB {GO:0043235=GO_REF:0000019, GO:0042734=GO_REF:0000039, GO:0008277=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000037, GO:0045211=GO_REF:0000039, GO:0051260=GO_REF:0000002} Q6ZWB6 BTB/POZ domain-containing protein KCTD8 protein 20130413 {GO:0043235=IEA, GO:0042734=IEA, GO:0008277=IEA, GO:0030054=IEA, GO:0005886=IEA, GO:0045211=IEA, GO:0051260=IEA} protein homooligomerization, regulation of G-protein coupled receptor protein signaling pathway cell junction, plasma membrane, postsynaptic membrane, presynaptic membrane, receptor complex Human UniProtKB-SubCell:SL-0219 KCTD9 InterPro UniProtKB {GO:0051260=GO_REF:0000002} Q7L273 BTB/POZ domain-containing protein KCTD9 protein 20130413 {GO:0051260=IEA} protein homooligomerization Human InterPro:IPR003131 KDELC1 UniProtKB UniProtKB {GO:0005788=GO_REF:0000024} Q6UW63 KDEL motif-containing protein 1 protein 20110907 {GO:0005788=ISS} endoplasmic reticulum lumen Human UniProtKB:Q9JHP7 KDELC2 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005788=GO_REF:0000039, GO:0005575=GO_REF:0000015} Q7Z4H8 KDEL motif-containing protein 2 protein 20101201 {GO:0003674=ND, GO:0008150=ND, GO:0005788=IEA, GO:0005575=ND} biological_process cellular_component, endoplasmic reticulum lumen molecular_function Human KDELR1 ENSEMBL UniProtKB {GO:0005801=GO_REF:0000019, GO:0005793=PMID:15308636, GO:0005794=GO_REF:0000019, GO:0046923=GO_REF:0000002, GO:0005783=GO_REF:0000019, GO:0015031=GO_REF:0000038, GO:0006886=PMID:2172835, GO:0016020=PMID:2172835, GO:0005789=GO_REF:0000039, GO:0006621=GO_REF:0000002, GO:0016021=GO_REF:0000038, GO:0016192=GO_REF:0000037, GO:0005046=PMID:2172835} Q8NBW7 ER lumen protein retaining receptor protein 20130413 {GO:0005801=IEA, GO:0005793=IDA, GO:0005794=IEA, GO:0046923=IEA, GO:0005783=IEA, GO:0015031=IEA, GO:0006886=TAS, GO:0016020=TAS, GO:0005789=IEA, GO:0006621=IEA, GO:0016021=IEA, GO:0016192=IEA, GO:0005046=TAS} intracellular protein transport, protein retention in ER lumen, protein transport, vesicle-mediated transport Golgi apparatus, cis-Golgi network, endoplasmic reticulum, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment, integral to membrane, membrane ER retention sequence binding, KDEL sequence binding Human Ensembl:ENSRNOP00000028627 KDELR2 PINC UniProtKB {GO:0005801=GO_REF:0000019, GO:0005794=PMID:1316805, GO:0046923=GO_REF:0000002, GO:0005783=PMID:1316805, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0006621=GO_REF:0000002, GO:0016192=GO_REF:0000037, GO:0006886=PMID:1325562, GO:0005046=PMID:1316805} P33947 ER lumen protein retaining receptor 2 protein 20030904 {GO:0005801=IEA, GO:0005794=TAS, GO:0046923=IEA, GO:0005783=TAS, GO:0005789=IEA, GO:0016021=IEA, GO:0006621=IEA, GO:0016192=IEA, GO:0006886=TAS, GO:0005046=TAS} intracellular protein transport, protein retention in ER lumen, vesicle-mediated transport Golgi apparatus, cis-Golgi network, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane ER retention sequence binding, KDEL sequence binding Human KDELR3 Reactome UniProtKB {GO:0046923=GO_REF:0000002, GO:0005789=Reactome:REACT_115630, GO:0016021=GO_REF:0000037, GO:0006621=GO_REF:0000002, GO:0006987=Reactome:REACT_18368, GO:0016192=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0030968=Reactome:REACT_18356} O43731 ER lumen protein retaining receptor 3 protein 20130301 {GO:0046923=IEA, GO:0005789=TAS, GO:0016021=IEA, GO:0006621=IEA, GO:0006987=TAS, GO:0016192=IEA, GO:0015031=IEA, GO:0044267=TAS, GO:0030968=TAS} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, protein retention in ER lumen, protein transport, vesicle-mediated transport endoplasmic reticulum membrane, integral to membrane ER retention sequence binding Human KDM1A BHF-UCL UniProtKB {GO:0005515=PMID:19497860, GO:0032454=PMID:20228790, GO:0032453=PMID:15620353, GO:0000790=PMID:20833138, GO:0003700=GO_REF:0000019, GO:0032452=PMID:19497860, GO:0044212=GO_REF:0000024, GO:0050681=PMID:16079795, GO:0045654=GO_REF:0000019, GO:0046886=GO_REF:0000019, GO:0034648=PMID:20228790, GO:2000179=GO_REF:0000019, GO:0000122=PMID:17805299, GO:0001701=GO_REF:0000019, GO:0043392=PMID:17805299, GO:0045648=GO_REF:0000019, GO:0006482=PMID:17805299, GO:0016491=PMID:15620353, GO:0005654=Reactome:REACT_25101, GO:0019899=PMID:17277772, GO:0045892=PMID:19497860, GO:0008134=PMID:20833138, GO:0032091=PMID:17805299, GO:0008283=GO_REF:0000019, GO:0050660=PMID:15620353, GO:0021983=GO_REF:0000019, GO:0005634=PMID:19497860, GO:0043433=PMID:17805299, GO:0002039=PMID:17805299, GO:0034720=PMID:20228790, GO:0051091=PMID:20833138, GO:0030374=PMID:16079795, GO:0045944=PMID:20833138, GO:0001085=GO_REF:0000019, GO:0030851=GO_REF:0000019, GO:0005667=GO_REF:0000024, GO:0043066=PMID:17805299, GO:0006355=GO_REF:0000002, GO:0006357=PMID:16079795, GO:0043426=PMID:20833138, GO:2000648=GO_REF:0000019, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0010725=GO_REF:0000019, GO:0032451=PMID:17805299, GO:0007596=Reactome:REACT_604, GO:0051573=GO_REF:0000019, GO:0003682=PMID:20228790, GO:0051572=GO_REF:0000019, GO:0043518=PMID:17805299, GO:0055001=PMID:20833138, GO:0033169=PMID:20228790} O60341 Lysine-specific histone demethylase 1A protein 20110126 {GO:0005515=IPI, GO:0032454=IDA, GO:0032453=IDA, GO:0000790=ISS, GO:0003700=IEA, GO:0032452=IDA, GO:0044212=ISS, GO:0050681=IDA, GO:0045654=IEA, GO:0046886=IEA, GO:0034648=IDA, GO:2000179=IEA, GO:0000122=IMP, GO:0001701=IEA, GO:0043392=IC, GO:0045648=IEA, GO:0006482=IMP, GO:0016491=IDA, GO:0005654=TAS, GO:0019899=IPI, GO:0045892=IDA, GO:0008134=IDA, GO:0032091=IMP, GO:0008283=IEA, GO:0050660=IDA, GO:0021983=IEA, GO:0005634=IDA, GO:0043433=IMP, GO:0002039=IPI, GO:0034720=IDA, GO:0051091=IDA, GO:0030374=IMP, GO:0045944=IDA, GO:0001085=IEA, GO:0030851=IEA, GO:0005667=ISS, GO:0043066=IMP, GO:0006355=IEA, GO:0006357=IMP, GO:0043426=IDA, GO:2000648=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0010725=IEA, GO:0032451=IMP, GO:0007596=TAS, GO:0051573=IEA, GO:0003682=IDA, GO:0051572=IEA, GO:0043518=IMP, GO:0055001=ISS, GO:0033169=IDA} blood coagulation, cell proliferation, granulocyte differentiation, histone H3-K4 demethylation, histone H3-K9 demethylation, in utero embryonic development, muscle cell development, negative regulation of DNA binding, negative regulation of DNA damage response, signal transduction by p53 class mediator, negative regulation of apoptotic process, negative regulation of histone H3-K4 methylation, negative regulation of histone H3-K9 methylation, negative regulation of protein binding, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, pituitary gland development, positive regulation of erythrocyte differentiation, positive regulation of hormone biosynthetic process, positive regulation of megakaryocyte differentiation, positive regulation of neural precursor cell proliferation, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of stem cell proliferation, positive regulation of transcription from RNA polymerase II promoter, protein demethylation, regulation of primitive erythrocyte differentiation, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription, DNA-dependent nuclear chromatin, nucleoplasm, nucleus, transcription factor complex DNA binding, MRF binding, RNA polymerase II transcription factor binding, androgen receptor binding, chromatin binding, demethylase activity, enzyme binding, flavin adenine dinucleotide binding, histone demethylase activity, histone demethylase activity (H3-K4 specific), histone demethylase activity (H3-K9 specific), histone demethylase activity (H3-dimethyl-K4 specific), ligand-dependent nuclear receptor transcription coactivator activity, oxidoreductase activity, p53 binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding Human UniProtKB:Q6ZQ88 KDM1B UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0050660=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0005634=PMID:19727073, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0034720=PMID:19727073, GO:0034648=PMID:19727073, GO:0044030=PMID:19727073, GO:0016491=GO_REF:0000037, GO:0006349=PMID:19727073, GO:0034649=PMID:19727073, GO:0008270=GO_REF:0000019, GO:0043046=GO_REF:0000019} Q8NB78 Lysine-specific histone demethylase 1B protein 20091210 {GO:0006355=IEA, GO:0050660=IEA, GO:0007275=IEA, GO:0005634=ISS, GO:0003677=IEA, GO:0006351=IEA, GO:0034720=ISS, GO:0034648=ISS, GO:0044030=ISS, GO:0016491=IEA, GO:0006349=ISS, GO:0034649=ISS, GO:0008270=IEA, GO:0043046=IEA} DNA methylation involved in gamete generation, histone H3-K4 demethylation, multicellular organismal development, regulation of DNA methylation, regulation of gene expression by genetic imprinting, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, flavin adenine dinucleotide binding, histone demethylase activity (H3-dimethyl-K4 specific), histone demethylase activity (H3-monomethyl-K4 specific), oxidoreductase activity, zinc ion binding Human UniProtKB:Q8CIG3 KDM2A MGI UniProtKB {GO:0045322=GO_REF:0000019, GO:0070544=PMID:20417597, GO:0000790=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0005654=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0016702=GO_REF:0000037, GO:0003677=GO_REF:0000002, GO:0051864=GO_REF:0000003, GO:0006351=GO_REF:0000037} Q9Y2K7 Lysine-specific demethylase 2A protein 20120213 {GO:0045322=IEA, GO:0070544=IMP, GO:0000790=IEA, GO:0006355=IEA, GO:0005654=IEA, GO:0008270=IEA, GO:0016702=IEA, GO:0003677=IEA, GO:0051864=IEA, GO:0006351=IEA} histone H3-K36 demethylation, regulation of transcription, DNA-dependent, transcription, DNA-dependent nuclear chromatin, nucleoplasm DNA binding, histone demethylase activity (H3-K36 specific), oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, unmethylated CpG binding, zinc ion binding Human KDM2B GOC UniProtKB {GO:0005515=PMID:16943429, GO:0035518=PMID:16943429, GO:0032452=PMID:21220025, GO:0021555=GO_REF:0000024, GO:0005634=PMID:10799292, GO:0007283=GO_REF:0000024, GO:0019843=GO_REF:0000037, GO:0048596=GO_REF:0000024, GO:0021678=GO_REF:0000024, GO:0043524=GO_REF:0000024, GO:0016577=PMID:21220025, GO:0031519=PMID:16943429, GO:2000178=GO_REF:0000024, GO:0021993=GO_REF:0000024, GO:0005730=GO_REF:0000039, GO:0000122=GO_REF:0000024, GO:0003677=PMID:10799292, GO:0051864=GO_REF:0000003, GO:0006351=GO_REF:0000037, GO:0021670=GO_REF:0000024, GO:0021592=GO_REF:0000024, GO:0030901=GO_REF:0000024, GO:0008270=GO_REF:0000029, GO:0030900=GO_REF:0000024, GO:0016702=GO_REF:0000037, GO:0030902=GO_REF:0000024} Q8NHM5 Lysine-specific demethylase 2B protein 20130413 {GO:0005515=IPI, GO:0035518=IDA, GO:0032452=TAS, GO:0021555=ISS, GO:0005634=NAS, GO:0007283=ISS, GO:0019843=IEA, GO:0048596=ISS, GO:0021678=ISS, GO:0043524=ISS, GO:0016577=TAS, GO:0031519=IDA, GO:2000178=ISS, GO:0021993=ISS, GO:0005730=IEA, GO:0000122=ISS, GO:0003677=NAS, GO:0051864=IEA, GO:0006351=IEA, GO:0021670=ISS, GO:0021592=ISS, GO:0030901=ISS, GO:0008270=NAS, GO:0030900=ISS, GO:0016702=IEA, GO:0030902=ISS} embryonic camera-type eye morphogenesis, forebrain development, fourth ventricle development, hindbrain development, histone H2A monoubiquitination, histone demethylation, initiation of neural tube closure, lateral ventricle development, midbrain development, midbrain-hindbrain boundary morphogenesis, negative regulation of neural precursor cell proliferation, negative regulation of neuron apoptotic process, negative regulation of transcription from RNA polymerase II promoter, spermatogenesis, third ventricle development, transcription, DNA-dependent PcG protein complex, nucleolus, nucleus DNA binding, histone demethylase activity, histone demethylase activity (H3-K36 specific), oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, protein binding, rRNA binding, zinc ion binding Human KDM3A UniProtKB UniProtKB {GO:0000976=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0005506=PMID:16603237, GO:0007290=GO_REF:0000019, GO:0001047=GO_REF:0000019, GO:0005634=PMID:16603237, GO:0050681=PMID:16603237, GO:0006351=GO_REF:0000037, GO:0046293=PMID:16603237, GO:0005737=GO_REF:0000039, GO:0009755=PMID:16603237, GO:0036123=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0051573=GO_REF:0000019, GO:0045893=PMID:16603237, GO:0016702=GO_REF:0000037, GO:0030521=PMID:16603237, GO:0033169=PMID:16603237} Q9Y4C1 Lysine-specific demethylase 3A protein 20080130 {GO:0000976=IEA, GO:0003700=IEA, GO:0005506=IMP, GO:0007290=IEA, GO:0001047=IEA, GO:0005634=IDA, GO:0050681=IDA, GO:0006351=IEA, GO:0046293=IDA, GO:0005737=IEA, GO:0009755=IDA, GO:0036123=IEA, GO:0045944=IEA, GO:0051573=IEA, GO:0045893=IMP, GO:0016702=IEA, GO:0030521=IDA, GO:0033169=IDA} androgen receptor signaling pathway, formaldehyde biosynthetic process, histone H3-K9 demethylation, histone H3-K9 dimethylation, hormone-mediated signaling pathway, negative regulation of histone H3-K9 methylation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, spermatid nucleus elongation, transcription, DNA-dependent cytoplasm, nucleus androgen receptor binding, core promoter binding, iron ion binding, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding Human KDM3B HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0016702=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q7LBC6 Lysine-specific demethylase 3B protein 20090616 {GO:0006355=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0016702=IEA, GO:0046872=IEA, GO:0006351=IEA, GO:0016568=IEA} chromatin modification, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus, nucleus metal ion binding, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen NOT Human KDM4A GOC UniProtKB {GO:0016577=PMID:16024779, GO:0005515=PMID:17567753, GO:0005813=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=PMID:16024779, GO:0035064=PMID:22373579, GO:0006351=GO_REF:0000037, GO:0051864=PMID:16024779, GO:0070544=PMID:16024779, GO:0005737=GO_REF:0000052, GO:0019048=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0016702=GO_REF:0000037, GO:0045892=PMID:16024779, GO:0031625=PMID:22373579} O75164 Lysine-specific demethylase 4A protein 20130413 {GO:0016577=IDA, GO:0005515=IPI, GO:0005813=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0035064=IDA, GO:0006351=IEA, GO:0051864=IDA, GO:0070544=IDA, GO:0005737=IDA, GO:0019048=IEA, GO:0008270=IEA, GO:0016702=IEA, GO:0045892=IDA, GO:0031625=IPI} histone H3-K36 demethylation, histone demethylation, negative regulation of transcription, DNA-dependent, transcription, DNA-dependent, virus-host interaction centrosome, cytoplasm, nucleolus, nucleus histone demethylase activity (H3-K36 specific), methylated histone residue binding, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, protein binding, ubiquitin protein ligase binding, zinc ion binding Human KDM4B UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0016702=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} O94953 Lysine-specific demethylase 4B protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0016702=IEA, GO:0006351=IEA, GO:0016568=IEA} chromatin modification, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, zinc ion binding Human UniProtKB-SubCell:SL-0191 KDM4C BHF-UCL UniProtKB {GO:0032454=PMID:17277772, GO:0008284=PMID:17277772, GO:0000790=PMID:17277772, GO:0006357=PMID:17277772, GO:0005634=GO_REF:0000038, GO:0008270=GO_REF:0000002, GO:0050681=PMID:17277772, GO:0016702=GO_REF:0000037, GO:0019899=PMID:17277772, GO:0006351=GO_REF:0000037, GO:0033169=PMID:17277772} Q9H3R0 Lysine-specific demethylase 4C protein 20110218 {GO:0032454=IMP, GO:0008284=IMP, GO:0000790=IDA, GO:0006357=IDA, GO:0005634=IEA, GO:0008270=IEA, GO:0050681=IPI, GO:0016702=IEA, GO:0019899=IPI, GO:0006351=IEA, GO:0033169=IMP} histone H3-K9 demethylation, positive regulation of cell proliferation, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nuclear chromatin, nucleus androgen receptor binding, enzyme binding, histone demethylase activity (H3-K9 specific), oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, zinc ion binding Human KDM4D UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0016702=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q6B0I6 Lysine-specific demethylase 4D protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0016702=IEA, GO:0046872=IEA, GO:0006351=IEA, GO:0016568=IEA} chromatin modification, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus metal ion binding, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Human UniProtKB-SubCell:SL-0191 KDM5A HPA UniProtKB {GO:0019907=PMID:11445587, GO:0003700=PMID:8414517, GO:0006366=PMID:8414517, GO:0005730=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0007275=GO_REF:0000037, GO:0003677=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0003682=GO_REF:0000019, GO:0016706=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0016702=GO_REF:0000037, GO:0045893=PMID:11358960, GO:0016568=GO_REF:0000037} P29375 Lysine-specific demethylase 5A protein 20101115 {GO:0019907=IDA, GO:0003700=TAS, GO:0006366=TAS, GO:0005730=IEA, GO:0005634=IDA, GO:0007275=IEA, GO:0003677=IEA, GO:0005737=IDA, GO:0003682=IEA, GO:0016706=IEA, GO:0008270=IEA, GO:0016702=IEA, GO:0045893=IDA, GO:0016568=IEA} chromatin modification, multicellular organismal development, positive regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter cyclin-dependent protein kinase activating kinase holoenzyme complex, cytoplasm, nucleolus, nucleus DNA binding, chromatin binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, sequence-specific DNA binding transcription factor activity, zinc ion binding Human KDM5B GOC UniProtKB {GO:0005515=PMID:12657635, GO:0003700=PMID:10336460, GO:0003714=PMID:12657635, GO:0005730=GO_REF:0000052, GO:0005634=PMID:12657635, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0034720=PMID:20228790, GO:0034721=PMID:20228790, GO:0034648=PMID:20228790, GO:0034647=PMID:20228790, GO:0016706=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0016702=GO_REF:0000037, GO:0045892=PMID:12657635} Q9UGL1 Lysine-specific demethylase 5B protein 20130413 {GO:0005515=IPI, GO:0003700=TAS, GO:0003714=IDA, GO:0005730=IDA, GO:0005634=TAS, GO:0003677=IEA, GO:0006351=IEA, GO:0043231=IDA, GO:0034720=IDA, GO:0034721=IDA, GO:0034648=IDA, GO:0034647=IDA, GO:0016706=IEA, GO:0008270=IEA, GO:0016702=IEA, GO:0045892=IDA} histone H3-K4 demethylation, histone H3-K4 demethylation, trimethyl-H3-K4-specific, negative regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular membrane-bounded organelle, nucleolus, nucleus DNA binding, histone demethylase activity (H3-dimethyl-K4 specific), histone demethylase activity (H3-trimethyl-K4 specific), oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, protein binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity, zinc ion binding Human KDM5C MGI UniProtKB {GO:0034720=PMID:17320160, GO:0032453=PMID:17320160, GO:0006355=GO_REF:0000037, GO:0016706=GO_REF:0000002, GO:0005634=PMID:18078810, GO:0008270=GO_REF:0000002, GO:0016702=GO_REF:0000037, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037} P41229 Lysine-specific demethylase 5C protein 20120213 {GO:0034720=IDA, GO:0032453=IDA, GO:0006355=IEA, GO:0016706=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0016702=IEA, GO:0003677=IEA, GO:0006351=IEA} histone H3-K4 demethylation, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, histone demethylase activity (H3-K4 specific), oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, zinc ion binding Human KDM5D MGI UniProtKB {GO:0003674=GO_REF:0000015, GO:0034720=PMID:17320160, GO:0032453=PMID:17320160, GO:0016706=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0007283=GO_REF:0000029, GO:0016702=GO_REF:0000037, GO:0003677=GO_REF:0000002} Q9BY66 Lysine-specific demethylase 5D protein 20120213 {GO:0003674=ND, GO:0034720=IDA, GO:0032453=IDA, GO:0016706=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0005575=ND, GO:0007283=NAS, GO:0016702=IEA, GO:0003677=IEA} histone H3-K4 demethylation, spermatogenesis cellular_component, nucleus DNA binding, histone demethylase activity (H3-K4 specific), molecular_function, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, zinc ion binding Human KDM6A MGI UniProtKB {GO:0035097=PMID:17500065, GO:0005634=PMID:17500065, GO:0016702=GO_REF:0000037, GO:0051568=PMID:17178841, GO:0046872=GO_REF:0000037} O15550 Lysine-specific demethylase 6A protein 20120418 {GO:0035097=IDA, GO:0005634=IDA, GO:0016702=IEA, GO:0051568=ISS, GO:0046872=IEA} histone H3-K4 methylation histone methyltransferase complex, nucleus metal ion binding, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Human KDM6B UniProtKB UniProtKB {GO:0043565=GO_REF:0000019, GO:0016577=GO_REF:0000019, GO:0006954=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0000122=GO_REF:0000019, GO:0016702=GO_REF:0000037, GO:0046872=GO_REF:0000037} O15054 Lysine-specific demethylase 6B protein 20130413 {GO:0043565=IEA, GO:0016577=IEA, GO:0006954=IEA, GO:0005634=IEA, GO:0000122=IEA, GO:0016702=IEA, GO:0046872=IEA} histone demethylation, inflammatory response, negative regulation of transcription from RNA polymerase II promoter nucleus metal ion binding, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, sequence-specific DNA binding Human UniProtKB-SubCell:SL-0191 KDR GOC UniProtKB {GO:0005515=PMID:22897854, GO:0035584=PMID:15215251, GO:0008360=PMID:7929439, GO:0051879=PMID:19267251, GO:0046777=PMID:10102632, GO:0043129=GO_REF:0000019, GO:0045446=GO_REF:0000019, GO:0070374=PMID:15215251, GO:0038084=PMID:15215251, GO:0038083=GO_REF:0000024, GO:0001945=GO_REF:0000019, GO:0023014=PMID:10022831, GO:0030335=PMID:7929439, GO:0048286=GO_REF:0000019, GO:0014068=PMID:9804796, GO:0018108=PMID:10102632, GO:0010595=PMID:10022831, GO:0005178=PMID:10022831, GO:0045165=GO_REF:0000019, GO:0005887=PMID:10102632, GO:0009897=GO_REF:0000019, GO:0035924=PMID:15215251, GO:0008284=PMID:7929439, GO:0005886=GO_REF:0000024, GO:0002042=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0051894=PMID:12820653, GO:0055074=GO_REF:0000019, GO:0050927=PMID:7929439, GO:0001541=GO_REF:0000019, GO:0019838=PMID:10022831, GO:0005021=PMID:10022831, GO:0048469=GO_REF:0000019, GO:0035162=GO_REF:0000024, GO:0048010=Reactome:REACT_12529, GO:0043066=PMID:15215251, GO:0003158=GO_REF:0000024, GO:0002053=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0001525=PMID:10022831, GO:0005524=GO_REF:0000037, GO:0045766=PMID:15215251, GO:0001938=PMID:10022831, GO:0019048=GO_REF:0000037, GO:0001934=PMID:19033661, GO:0016023=GO_REF:0000039, GO:0004713=PMID:10037737, GO:0048754=GO_REF:0000019, GO:0004714=PMID:1417831, GO:0051770=PMID:9837777, GO:2000352=PMID:9804796, GO:0043410=PMID:11387210, GO:0001570=GO_REF:0000024, GO:0007169=PMID:1417831, GO:0005769=GO_REF:0000024, GO:0004716=PMID:10022831} P35968 Vascular endothelial growth factor receptor 2 protein 20130413 {GO:0005515=IPI, GO:0035584=IMP, GO:0008360=IDA, GO:0051879=TAS, GO:0046777=IDA, GO:0043129=IEA, GO:0045446=IEA, GO:0070374=IMP, GO:0038084=IDA, GO:0038083=ISS, GO:0001945=IEA, GO:0023014=TAS, GO:0030335=IDA, GO:0048286=IEA, GO:0014068=IDA, GO:0018108=IDA, GO:0010595=IMP, GO:0005178=IPI, GO:0045165=IEA, GO:0005887=IDA, GO:0009897=IEA, GO:0035924=IMP, GO:0008284=IDA, GO:0005886=ISS, GO:0002042=ISS, GO:0005634=IEA, GO:0051894=IDA, GO:0055074=IEA, GO:0050927=IDA, GO:0001541=IEA, GO:0019838=IPI, GO:0005021=IDA, GO:0048469=IEA, GO:0035162=ISS, GO:0048010=TAS, GO:0043066=IMP, GO:0003158=ISS, GO:0002053=IEA, GO:0005576=IEA, GO:0001525=TAS, GO:0005524=IEA, GO:0045766=IMP, GO:0001938=IMP, GO:0019048=IEA, GO:0001934=IDA, GO:0016023=IEA, GO:0004713=IDA, GO:0048754=IEA, GO:0004714=TAS, GO:0051770=IMP, GO:2000352=IDA, GO:0043410=IDA, GO:0001570=ISS, GO:0007169=TAS, GO:0005769=ISS, GO:0004716=TAS} angiogenesis, branching morphogenesis of an epithelial tube, calcium ion homeostasis, calcium-mediated signaling using intracellular calcium source, cell fate commitment, cell maturation, cell migration involved in sprouting angiogenesis, cellular response to vascular endothelial growth factor stimulus, embryonic hemopoiesis, endothelial cell differentiation, endothelium development, lung alveolus development, lymph vessel development, negative regulation of apoptotic process, negative regulation of endothelial cell apoptotic process, ovarian follicle development, peptidyl-tyrosine autophosphorylation, peptidyl-tyrosine phosphorylation, positive regulation of ERK1 and ERK2 cascade, positive regulation of MAPK cascade, positive regulation of angiogenesis, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of endothelial cell migration, positive regulation of endothelial cell proliferation, positive regulation of focal adhesion assembly, positive regulation of mesenchymal cell proliferation, positive regulation of nitric-oxide synthase biosynthetic process, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of positive chemotaxis, positive regulation of protein phosphorylation, protein autophosphorylation, regulation of cell shape, signal transduction by phosphorylation, surfactant homeostasis, transmembrane receptor protein tyrosine kinase signaling pathway, vascular endothelial growth factor receptor signaling pathway, vascular endothelial growth factor signaling pathway, vasculogenesis, virus-host interaction cytoplasmic membrane-bounded vesicle, early endosome, external side of plasma membrane, extracellular region, integral to plasma membrane, nucleus, plasma membrane ATP binding, Hsp90 protein binding, growth factor binding, integrin binding, protein binding, protein tyrosine kinase activity, receptor signaling protein tyrosine kinase activity, transmembrane receptor protein tyrosine kinase activity, vascular endothelial growth factor-activated receptor activity Human KDSR Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0047560=PMID:15364918, GO:0006666=PMID:15364918, GO:0005783=PMID:15364918, GO:0030148=Reactome:REACT_115810, GO:0005789=Reactome:REACT_19162, GO:0016491=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0005615=PMID:8417785} Q06136 3-ketodihydrosphingosine reductase protein 20130301 {GO:0006665=TAS, GO:0047560=IDA, GO:0006666=IDA, GO:0005783=IDA, GO:0030148=TAS, GO:0005789=TAS, GO:0016491=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0005615=TAS} 3-keto-sphinganine metabolic process, small molecule metabolic process, sphingolipid biosynthetic process, sphingolipid metabolic process endoplasmic reticulum, endoplasmic reticulum membrane, extracellular space, integral to membrane 3-dehydrosphinganine reductase activity, oxidoreductase activity Human KEAP1 HPA UniProtKB {GO:0005515=PMID:21988832, GO:0005813=GO_REF:0000052, GO:0006355=GO_REF:0000019, GO:0016567=PMID:15983046, GO:0005783=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0030496=PMID:15166316, GO:0005634=GO_REF:0000052, GO:0001701=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0031463=PMID:15983046, GO:0045604=GO_REF:0000019, GO:0010499=PMID:15983046} Q14145 Kelch-like ECH-associated protein 1 protein 20080818 {GO:0005515=IPI, GO:0005813=IDA, GO:0006355=IEA, GO:0016567=IDA, GO:0005783=IEA, GO:0005730=IDA, GO:0030496=IDA, GO:0005634=IDA, GO:0001701=IEA, GO:0006351=IEA, GO:0005737=IDA, GO:0031463=IDA, GO:0045604=IEA, GO:0010499=IDA} in utero embryonic development, proteasomal ubiquitin-independent protein catabolic process, protein ubiquitination, regulation of epidermal cell differentiation, regulation of transcription, DNA-dependent, transcription, DNA-dependent Cul3-RING ubiquitin ligase complex, centrosome, cytoplasm, endoplasmic reticulum, midbody, nucleolus, nucleus protein binding Human KEL HGNC UniProtKB {GO:0005515=PMID:7737196, GO:0005886=GO_REF:0000039, GO:0042310=PMID:15769748, GO:0006508=GO_REF:0000037, GO:0016021=PMID:9647734, GO:0004222=PMID:15769748, GO:0046872=GO_REF:0000037} P23276 Kell blood group glycoprotein protein 20100205 {GO:0005515=IPI, GO:0005886=IEA, GO:0042310=TAS, GO:0006508=IEA, GO:0016021=TAS, GO:0004222=IDA, GO:0046872=IEA} proteolysis, vasoconstriction integral to membrane, plasma membrane metal ion binding, metalloendopeptidase activity, protein binding Human KERA Reactome UniProtKB {GO:0005796=Reactome:REACT_121317, GO:0005975=Reactome:REACT_474, GO:0005578=PMID:10802664, GO:0005576=Reactome:REACT_121303, GO:0044281=Reactome:REACT_111217, GO:0042339=Reactome:REACT_121288, GO:0061303=GO_REF:0000019, GO:0003674=GO_REF:0000015, GO:0018146=Reactome:REACT_121120, GO:0042340=Reactome:REACT_121313, GO:0007601=GO_REF:0000037, GO:0030203=Reactome:REACT_121315, GO:0050896=GO_REF:0000037, GO:0043202=Reactome:REACT_121303} O60938 Keratocan protein 20130301 {GO:0005796=TAS, GO:0005975=TAS, GO:0005578=NAS, GO:0005576=TAS, GO:0044281=TAS, GO:0042339=TAS, GO:0061303=IEA, GO:0003674=ND, GO:0018146=TAS, GO:0042340=TAS, GO:0007601=IEA, GO:0030203=TAS, GO:0050896=IEA, GO:0043202=TAS} carbohydrate metabolic process, cornea development in camera-type eye, glycosaminoglycan metabolic process, keratan sulfate biosynthetic process, keratan sulfate catabolic process, keratan sulfate metabolic process, response to stimulus, small molecule metabolic process, visual perception Golgi lumen, extracellular region, lysosomal lumen, proteinaceous extracellular matrix molecular_function Human KHDRBS1 IntAct UniProtKB {GO:0006397=PMID:1374686, GO:0005515=PMID:21988832, GO:0017124=GO_REF:0000019, GO:0008283=PMID:9013542, GO:0003723=PMID:1374686, GO:0005634=PMID:1374686, GO:0003677=PMID:1374686, GO:0032403=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0007165=PMID:9013542, GO:0005737=GO_REF:0000019, GO:0031647=PMID:21613532, GO:0016020=PMID:1374686, GO:0000086=GO_REF:0000024, GO:0005070=PMID:9045636, GO:0070618=GO_REF:0000019, GO:0007050=PMID:9013542, GO:0045948=PMID:21613532, GO:0046833=PMID:21613532, GO:0046831=GO_REF:0000024, GO:0045892=GO_REF:0000024, GO:0007166=PMID:9045636} Q07666 KH domain-containing, RNA-binding, signal transduction-associated protein 1 protein 20130415 {GO:0006397=TAS, GO:0005515=IPI, GO:0017124=IEA, GO:0008283=TAS, GO:0003723=IDA, GO:0005634=IDA, GO:0003677=TAS, GO:0032403=IEA, GO:0006351=IEA, GO:0007165=TAS, GO:0005737=IEA, GO:0031647=IDA, GO:0016020=IDA, GO:0000086=ISS, GO:0005070=IPI, GO:0070618=IEA, GO:0007050=TAS, GO:0045948=IDA, GO:0046833=IDA, GO:0046831=ISS, GO:0045892=ISS, GO:0007166=IDA} G2/M transition of mitotic cell cycle, cell cycle arrest, cell proliferation, cell surface receptor signaling pathway, mRNA processing, negative regulation of transcription, DNA-dependent, positive regulation of RNA export from nucleus, positive regulation of translational initiation, regulation of RNA export from nucleus, regulation of protein stability, signal transduction, transcription, DNA-dependent Grb2-Sos complex, cytoplasm, membrane, nucleus DNA binding, RNA binding, SH3 domain binding, SH3/SH2 adaptor activity, protein binding, protein complex binding Human UniProtKB:P62993 KHDRBS2 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0008266=GO_REF:0000019, GO:0017124=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0046982=GO_REF:0000019, GO:0008143=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0042169=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q5VWX1 KH domain-containing, RNA-binding, signal transduction-associated protein 2 protein 20130415 {GO:0005515=IPI, GO:0008266=IEA, GO:0017124=IEA, GO:0006355=IEA, GO:0046982=IEA, GO:0008143=IEA, GO:0005634=IEA, GO:0042169=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus SH2 domain binding, SH3 domain binding, poly(A) RNA binding, poly(U) RNA binding, protein binding, protein heterodimerization activity Human UniProtKB:P38159 KHDRBS3 HPA UniProtKB {GO:0005515=PMID:20195357, GO:0017124=GO_REF:0000037, GO:0006355=GO_REF:0000037, GO:0003723=PMID:19561594, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0007283=PMID:10332027, GO:0006351=GO_REF:0000037} O75525 KH domain-containing, RNA-binding, signal transduction-associated protein 3 protein 20080205 {GO:0005515=IPI, GO:0017124=IEA, GO:0006355=IEA, GO:0003723=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0007283=TAS, GO:0006351=IEA} regulation of transcription, DNA-dependent, spermatogenesis, transcription, DNA-dependent nucleolus, nucleus RNA binding, SH3 domain binding, protein binding NOT Human KHK HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005975=Reactome:REACT_474, GO:0044281=Reactome:REACT_111217, GO:0004454=Reactome:REACT_1927, GO:0005524=GO_REF:0000037, GO:0006001=Reactome:REACT_1571, GO:0005829=Reactome:REACT_1927} P50053 Ketohexokinase protein 20080205 {GO:0005737=IDA, GO:0005975=TAS, GO:0044281=TAS, GO:0004454=EXP, GO:0005524=IEA, GO:0006001=TAS, GO:0005829=TAS} carbohydrate metabolic process, fructose catabolic process, small molecule metabolic process cytoplasm, cytosol ATP binding, ketohexokinase activity Human KHNYN BHF-UCL UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} O15037 Protein KHNYN protein 20130118 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human KHSRP HPA UniProtKB {GO:0006397=GO_REF:0000037, GO:0008380=PMID:10911989, GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000037, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0010494=GO_REF:0000019, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0005829=Reactome:REACT_25257, GO:0000375=PMID:10911989, GO:0005654=Reactome:REACT_25152, GO:0051028=GO_REF:0000037} Q92945 Far upstream element-binding protein 2 protein 20101115 {GO:0006397=IEA, GO:0008380=TAS, GO:0010467=TAS, GO:0006355=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0010494=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA, GO:0005829=TAS, GO:0000375=TAS, GO:0005654=TAS, GO:0051028=IEA} RNA metabolic process, RNA splicing, RNA splicing, via transesterification reactions, gene expression, mRNA metabolic process, mRNA processing, mRNA transport, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasmic stress granule, cytosol, nucleolus, nucleoplasm, nucleus DNA binding, RNA binding NOT Human KIAA0020 HPA UniProtKB {GO:0005783=PMID:10942595, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052} Q15397 Pumilio domain-containing protein KIAA0020 protein 20080205 {GO:0005783=IDA, GO:0003723=IEA, GO:0005730=IDA} endoplasmic reticulum, nucleolus RNA binding Human KIAA0100 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q14667 UPF0378 protein KIAA0100 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 KIAA0101 UniProtKB UniProtKB {GO:0006260=PMID:23000965, GO:0005515=PMID:21628590, GO:0051297=PMID:21673012, GO:0048471=PMID:21673012, GO:0003682=PMID:23000965, GO:0051726=PMID:21628590, GO:0005634=PMID:21628590, GO:0019985=PMID:23000965, GO:0009411=PMID:23000965, GO:0006974=PMID:21628590} Q15004 PCNA-associated factor protein 20121022 {GO:0006260=IDA, GO:0005515=IPI, GO:0051297=IMP, GO:0048471=IDA, GO:0003682=IDA, GO:0051726=IMP, GO:0005634=IDA, GO:0019985=IMP, GO:0009411=IDA, GO:0006974=IDA} DNA replication, centrosome organization, regulation of cell cycle, response to DNA damage stimulus, response to UV, translesion synthesis nucleus, perinuclear region of cytoplasm chromatin binding, protein binding Human UniProtKB:P12004 KIAA0195 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q12767 Uncharacterized protein KIAA0195 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 KIAA0196 UniProtKB UniProtKB {GO:0008219=GO_REF:0000037, GO:0016197=GO_REF:0000019, GO:0071203=PMID:19922875, GO:0005768=GO_REF:0000019} Q12768 WASH complex subunit strumpellin protein 20091127 {GO:0008219=IEA, GO:0016197=IEA, GO:0071203=IDA, GO:0005768=IEA} cell death, endosomal transport WASH complex, endosome Human KIAA0226 UniProtKB UniProtKB {GO:0005515=PMID:19270696, GO:0005794=PMID:19270696, GO:0005770=PMID:19270696, GO:0045806=PMID:19270696, GO:0010507=PMID:19270696, GO:0006914=GO_REF:0000037, GO:0005764=GO_REF:0000039, GO:0005769=PMID:19270696, GO:0006897=GO_REF:0000037} Q92622 Run domain Beclin-1 interacting and cystein-rich containing protein protein 20100625 {GO:0005515=IPI, GO:0005794=IDA, GO:0005770=IDA, GO:0045806=IMP, GO:0010507=IMP, GO:0006914=IEA, GO:0005764=IEA, GO:0005769=IDA, GO:0006897=IEA} autophagy, endocytosis, negative regulation of autophagy, negative regulation of endocytosis Golgi apparatus, early endosome, late endosome, lysosome protein binding Human UniProtKB:Q8NEB9 KIAA0226L null null {} null null null null {} null null null KIAA0232 UniProtKB UniProtKB {GO:0005524=GO_REF:0000037} Q92628 Uncharacterized protein KIAA0232 protein 20130413 {GO:0005524=IEA} ATP binding Human UniProtKB-KW:KW-0067 KIAA0247 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} Q92537 Uncharacterized protein KIAA0247 protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND, GO:0016021=IEA} biological_process cellular_component, integral to membrane molecular_function Human KIAA0319 UniProtKB UniProtKB {GO:0005515=PMID:19419997, GO:0005886=PMID:19419997, GO:0031901=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0001764=PMID:19679544, GO:2000171=PMID:19679544, GO:0005769=PMID:19419997} Q5VV43 Dyslexia-associated protein KIAA0319 protein 20101110 {GO:0005515=IPI, GO:0005886=IDA, GO:0031901=IEA, GO:0016021=IEA, GO:0001764=IGI, GO:2000171=IGI, GO:0005769=IDA} negative regulation of dendrite development, neuron migration early endosome, early endosome membrane, integral to membrane, plasma membrane protein binding Human KIAA0368 null null {} null null null null {} null null null KIAA0391 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0008033=GO_REF:0000037} O15091 Mitochondrial ribonuclease P protein 3 protein 20130413 {GO:0005739=IEA, GO:0008033=IEA} tRNA processing mitochondrion Human UniProtKB-SubCell:SL-0173 KIAA0408 IntAct UniProtKB {GO:0005515=PMID:20195357} Q6ZU52 Uncharacterized protein KIAA0408 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:P04150 KIAA0430 UniProtKB UniProtKB {GO:0010468=GO_REF:0000024, GO:0003674=GO_REF:0000015, GO:0048477=GO_REF:0000024, GO:0000166=GO_REF:0000002, GO:0010923=PMID:19389623, GO:0003723=GO_REF:0000037, GO:0007143=GO_REF:0000024, GO:0003676=GO_REF:0000002, GO:0030154=GO_REF:0000037, GO:0005777=PMID:15932519} Q9Y4F3 Meiosis arrest female protein 1 protein 20120430 {GO:0010468=ISS, GO:0003674=ND, GO:0048477=ISS, GO:0000166=IEA, GO:0010923=IDA, GO:0003723=IEA, GO:0007143=ISS, GO:0003676=IEA, GO:0030154=IEA, GO:0005777=IDA} cell differentiation, female meiosis, negative regulation of phosphatase activity, oogenesis, regulation of gene expression peroxisome RNA binding, molecular_function, nucleic acid binding, nucleotide binding Human UniProtKB:Q8BJ34 KIAA0513 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} O60268 Uncharacterized protein KIAA0513 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 KIAA0556 HPA UniProtKB {GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} O60303 Uncharacterized protein KIAA0556 protein 20111111 {GO:0005886=IDA, GO:0005730=IDA, GO:0005634=IDA} nucleolus, nucleus, plasma membrane Human KIAA0586 UniProtKB UniProtKB {GO:0005813=PMID:19144723, GO:0005737=GO_REF:0000037, GO:0060271=GO_REF:0000024, GO:0007224=GO_REF:0000024} Q9BVV6 Protein TALPID3 protein 20120925 {GO:0005813=IDA, GO:0005737=IEA, GO:0060271=ISS, GO:0007224=ISS} cilium morphogenesis, smoothened signaling pathway centrosome, cytoplasm Human UniProtKB:E9PV87 KIAA0753 HPA UniProtKB {GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052} Q2KHM9 Uncharacterized protein KIAA0753 protein 20101115 {GO:0005813=IDA, GO:0005737=IDA} centrosome, cytoplasm Human KIAA0754 null null {} null null null null {} null null null KIAA0825 null null {} null null null null {} null null null KIAA0895 null null {} null null null null {} null null null KIAA0907 null null {} null null null null {} null null null KIAA0922 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} A2VDJ0 Transmembrane protein 131-like protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 KIAA0930 null null {} null null null null {} null null null KIAA0947 null null {} null null null null {} null null null KIAA1009 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005813=PMID:21399614, GO:0007067=GO_REF:0000037, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005819=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0051301=GO_REF:0000037} Q5TB80 Protein QN1 homolog protein 20101115 {GO:0005737=IDA, GO:0005813=IDA, GO:0007067=IEA, GO:0005886=IDA, GO:0005730=IDA, GO:0005819=IEA, GO:0005634=IDA, GO:0051301=IEA} cell division, mitosis centrosome, cytoplasm, nucleolus, nucleus, plasma membrane, spindle Human KIAA1033 MGI UniProtKB {GO:0016197=PMID:20923837, GO:0071203=PMID:19922875, GO:0005768=PMID:20923837} Q2M389 WASH complex subunit 7 protein 20120912 {GO:0016197=IMP, GO:0071203=IDA, GO:0005768=IDA} endosomal transport WASH complex, endosome Human KIAA1107 null null {} null null null null {} null null null KIAA1109 BHF-UCL UniProtKB {GO:0005515=PMID:20195357, GO:0030856=PMID:17190194, GO:0016020=PMID:16632497, GO:0005634=PMID:17190194, GO:0016021=GO_REF:0000037, GO:0001558=PMID:17190194} Q2LD37 Uncharacterized protein KIAA1109 protein 20110128 {GO:0005515=IPI, GO:0030856=NAS, GO:0016020=NAS, GO:0005634=NAS, GO:0016021=IEA, GO:0001558=NAS} regulation of cell growth, regulation of epithelial cell differentiation integral to membrane, membrane, nucleus protein binding Human KIAA1143 null null {} null null null null {} null null null KIAA1147 null null {} null null null null {} null null null KIAA1161 ENSEMBL UniProtKB {GO:0051897=GO_REF:0000019, GO:0031965=GO_REF:0000019, GO:0043568=GO_REF:0000019, GO:0005975=GO_REF:0000002, GO:0048741=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0004553=GO_REF:0000002} Q6NSJ0 Uncharacterized family 31 glucosidase KIAA1161 protein 20130413 {GO:0051897=IEA, GO:0031965=IEA, GO:0043568=IEA, GO:0005975=IEA, GO:0048741=IEA, GO:0016021=IEA, GO:0004553=IEA} carbohydrate metabolic process, positive regulation of insulin-like growth factor receptor signaling pathway, positive regulation of protein kinase B signaling cascade, skeletal muscle fiber development integral to membrane, nuclear membrane hydrolase activity, hydrolyzing O-glycosyl compounds Human Ensembl:ENSMUSP00000059038 KIAA1191 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000024, GO:0016491=GO_REF:0000037, GO:0005575=GO_REF:0000015} Q96A73 Putative monooxygenase p33MONOX protein 20120305 {GO:0008150=ND, GO:0003674=ND, GO:0005737=ISS, GO:0016491=IEA, GO:0005575=ND} biological_process cellular_component, cytoplasm molecular_function, oxidoreductase activity Human UniProtKB:Q9DBN4 KIAA1199 ENSEMBL UniProtKB {GO:0005737=GO_REF:0000019} Q8WUJ3 Protein KIAA1199 protein 20130413 {GO:0005737=IEA} cytoplasm Human Ensembl:ENSMUSP00000063277 KIAA1211 null null {} null null null null {} null null null KIAA1217 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000024, GO:0048706=GO_REF:0000024} Q5T5P2 Sickle tail protein homolog protein 20070423 {GO:0003674=ND, GO:0005737=ISS, GO:0048706=ISS} embryonic skeletal system development cytoplasm molecular_function Human UniProtKB:A2AQ25 KIAA1244 null null {} null null null null {} null null null KIAA1279 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0005739=PMID:16225668, GO:0019894=PMID:16225668, GO:0006839=PMID:16225668, GO:0030154=GO_REF:0000037, GO:0007399=GO_REF:0000037} Q96EK5 KIF1-binding protein protein 20130415 {GO:0005515=IPI, GO:0005739=IDA, GO:0019894=IPI, GO:0006839=IMP, GO:0030154=IEA, GO:0007399=IEA} cell differentiation, mitochondrial transport, nervous system development mitochondrion kinesin binding, protein binding Human UniProtKB:P47804 KIAA1324 BHF-UCL UniProtKB {GO:0005802=PMID:21072319, GO:0003674=GO_REF:0000015, GO:0005887=PMID:21072319, GO:0005770=PMID:21072319, GO:0016236=PMID:21072319, GO:2000786=PMID:21072319, GO:0042981=PMID:21072319, GO:0044090=PMID:21072319, GO:0005764=PMID:21072319} Q6UXG2 UPF0577 protein KIAA1324 protein 20110615 {GO:0005802=IDA, GO:0003674=ND, GO:0005887=IDA, GO:0005770=IDA, GO:0016236=IMP, GO:2000786=IMP, GO:0042981=IMP, GO:0044090=IMP, GO:0005764=IDA} macroautophagy, positive regulation of autophagic vacuole assembly, positive regulation of vacuole organization, regulation of apoptotic process integral to plasma membrane, late endosome, lysosome, trans-Golgi network molecular_function colocalizes_with Human KIAA1328 null null {} null null null null {} null null null KIAA1377 IntAct UniProtKB {GO:0005515=PMID:15383276} Q9P2H0 Uncharacterized protein KIAA1377 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:Q9Y2X7 KIAA1407 null null {} null null null null {} null null null KIAA1429 UniProtKB UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0005634=GO_REF:0000039} Q69YN4 Protein virilizer homolog protein 20130413 {GO:0008380=IEA, GO:0006397=IEA, GO:0005634=IEA} RNA splicing, mRNA processing nucleus Human UniProtKB-SubCell:SL-0191 KIAA1430 null null {} null null null null {} null null null KIAA1432 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q4ADV7 Protein RIC1 homolog protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 KIAA1467 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} A2RU67 Uncharacterized protein KIAA1467 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 KIAA1468 null null {} null null null null {} null null null KIAA1522 null null {} null null null null {} null null null KIAA1524 HPA UniProtKB {GO:0005515=PMID:17632056, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0016021=GO_REF:0000037} Q8TCG1 Protein CIP2A protein 20110516 {GO:0005515=IPI, GO:0005737=IDA, GO:0005886=IDA, GO:0016021=IEA} cytoplasm, integral to membrane, plasma membrane protein binding Human KIAA1549 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9HCM3 UPF0606 protein KIAA1549 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 KIAA1586 InterPro UniProtKB {GO:0003676=GO_REF:0000002} Q9HCI6 Uncharacterized protein KIAA1586 protein 20130413 {GO:0003676=IEA} nucleic acid binding Human InterPro:IPR012337 KIAA1598 Reactome UniProtKB {GO:0030424=GO_REF:0000039, GO:0007411=Reactome:REACT_18266, GO:0019900=GO_REF:0000002} A0MZ66 Shootin-1 protein 20091012 {GO:0030424=IEA, GO:0007411=TAS, GO:0019900=IEA} axon guidance axon kinase binding Human KIAA1671 null null {} null null null null {} null null null KIAA1683 LIFEdb UniProtKB {GO:0005739=GO_REF:0000054} Q9H0B3 Uncharacterized protein KIAA1683 protein 20100607 {GO:0005739=IDA} mitochondrion Human KIAA1715 ENSEMBL UniProtKB {GO:0007596=GO_REF:0000019, GO:0035115=GO_REF:0000019, GO:0042733=GO_REF:0000019} C9JM95 Protein KIAA1715 protein 20130413 {GO:0007596=IEA, GO:0035115=IEA, GO:0042733=IEA} blood coagulation, embryonic digit morphogenesis, embryonic forelimb morphogenesis Human Ensembl:ENSMUSP00000066891 KIAA1731 UniProtKB UniProtKB {GO:0005737=PMID:20844083, GO:0005813=PMID:20844083, GO:0005856=PMID:20844083} Q9C0D2 Centrosomal protein KIAA1731 protein 20110816 {GO:0005737=IDA, GO:0005813=IDA, GO:0005856=IDA} centrosome, cytoplasm, cytoskeleton Human KIAA1737 null null {} null null null null {} null null null KIAA1841 null null {} null null null null {} null null null KIAA1875 null null {} null null null null {} null null null KIAA1958 null null {} null null null null {} null null null KIAA1967 GOC UniProtKB {GO:0008380=PMID:22446626, GO:0006397=GO_REF:0000037, GO:0004857=PMID:18235502, GO:0044609=PMID:22446626, GO:0005515=PMID:22190034, GO:0043065=PMID:18235502, GO:0000993=PMID:22446626, GO:0006915=PMID:15824730, GO:0005634=GO_REF:0000054, GO:0043086=PMID:19218236, GO:0005737=PMID:15824730, GO:0032784=PMID:22446626, GO:0005759=PMID:15824730, GO:0005681=PMID:22446626, GO:0019899=PMID:18235501} Q8N163 DBIRD complex subunit KIAA1967 protein 20130413 {GO:0008380=IMP, GO:0006397=IEA, GO:0004857=IDA, GO:0044609=IDA, GO:0005515=IPI, GO:0043065=IMP, GO:0000993=IDA, GO:0006915=IDA, GO:0005634=IDA, GO:0043086=IMP, GO:0005737=IDA, GO:0032784=IMP, GO:0005759=IDA, GO:0005681=IDA, GO:0019899=IPI} RNA splicing, apoptotic process, mRNA processing, negative regulation of catalytic activity, positive regulation of apoptotic process, regulation of DNA-dependent transcription, elongation DBIRD complex, cytoplasm, mitochondrial matrix, nucleus, spliceosomal complex RNA polymerase II core binding, enzyme binding, enzyme inhibitor activity, protein binding Human UniProtKB:O43463 KIAA1984 null null {} null null null null {} null null null KIAA2013 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8IYS2 Uncharacterized protein KIAA2013 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 KIAA2018 UniProtKB UniProtKB {GO:0016020=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0004571=GO_REF:0000002, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037} Q68DE3 Basic helix-loop-helix domain-containing protein KIAA2018 protein 20130413 {GO:0016020=IEA, GO:0005509=IEA, GO:0004571=IEA, GO:0046983=IEA, GO:0005634=IEA, GO:0003677=IEA} membrane, nucleus DNA binding, calcium ion binding, mannosyl-oligosaccharide 1,2-alpha-mannosidase activity, protein dimerization activity Human UniProtKB-SubCell:SL-0191 KIAA2022 RefGenome UniProtKB {GO:0043625=GO_REF:0000033, GO:0000084=GO_REF:0000033, GO:0007346=GO_REF:0000033, GO:0008408=GO_REF:0000033, GO:0045004=GO_REF:0000033, GO:0003887=GO_REF:0000033, GO:0006287=GO_REF:0000033, GO:0006297=GO_REF:0000033, GO:0005634=GO_REF:0000033, GO:0043137=GO_REF:0000033, GO:0019985=GO_REF:0000033} Q5QGS0 Uncharacterized protein KIAA2022 protein 20110104 {GO:0043625=IBA, GO:0000084=IBA, GO:0007346=IBA, GO:0008408=IBA, GO:0045004=IBA, GO:0003887=IBA, GO:0006287=IBA, GO:0006297=IBA, GO:0005634=IBA, GO:0043137=IBA, GO:0019985=IBA} DNA replication proofreading, DNA replication, removal of RNA primer, S phase of mitotic cell cycle, base-excision repair, gap-filling, nucleotide-excision repair, DNA gap filling, regulation of mitotic cell cycle, translesion synthesis delta DNA polymerase complex, nucleus 3'-5' exonuclease activity, DNA-directed DNA polymerase activity Human PANTHER:PTN000035478 KIAA2026 null null {} null null null null {} null null null KIDINS220 Reactome UniProtKB {GO:0048813=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0000186=Reactome:REACT_12005, GO:0016021=GO_REF:0000037, GO:0001701=GO_REF:0000019, GO:0005829=Reactome:REACT_12066} Q9ULH0 Kinase D-interacting substrate of 220 kDa protein 20130213 {GO:0048813=IEA, GO:0048011=TAS, GO:0000186=TAS, GO:0016021=IEA, GO:0001701=IEA, GO:0005829=TAS} activation of MAPKK activity, dendrite morphogenesis, in utero embryonic development, neurotrophin TRK receptor signaling pathway cytosol, integral to membrane Human KIF11 HPA UniProtKB {GO:0008017=GO_REF:0000002, GO:0005871=PMID:8548803, GO:0007100=GO_REF:0000019, GO:0019901=PMID:19001501, GO:0005874=PMID:21525035, GO:0005819=PMID:19001501, GO:0003777=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_120995, GO:0019886=Reactome:REACT_121399, GO:0005737=GO_REF:0000052, GO:0000922=PMID:14718566, GO:0007067=PMID:8548803, GO:0007596=Reactome:REACT_604, GO:0005876=PMID:14718566, GO:0007051=PMID:14718566, GO:0090307=PMID:19001501, GO:0007052=PMID:8548803, GO:0007018=Reactome:REACT_25201, GO:0051301=GO_REF:0000037} P52732 Kinesin-like protein KIF11 protein 20101115 {GO:0008017=IEA, GO:0005871=TAS, GO:0007100=IEA, GO:0019901=IPI, GO:0005874=IDA, GO:0005819=IDA, GO:0003777=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0019886=TAS, GO:0005737=IDA, GO:0000922=IDA, GO:0007067=TAS, GO:0007596=TAS, GO:0005876=IDA, GO:0007051=IMP, GO:0090307=IDA, GO:0007052=TAS, GO:0007018=TAS, GO:0051301=IEA} antigen processing and presentation of exogenous peptide antigen via MHC class II, blood coagulation, cell division, microtubule-based movement, mitosis, mitotic centrosome separation, mitotic spindle organization, spindle assembly involved in mitosis, spindle organization cytoplasm, cytosol, kinesin complex, microtubule, spindle, spindle microtubule, spindle pole ATP binding, microtubule binding, microtubule motor activity, protein kinase binding Human KIF13A UniProtKB UniProtKB {GO:0005515=PMID:20208530, GO:0005813=PMID:20208530, GO:0035459=PMID:19841138, GO:0043001=GO_REF:0000024, GO:0005875=GO_REF:0000002, GO:0032438=PMID:19841138, GO:0005874=GO_REF:0000037, GO:0008333=PMID:19841138, GO:0072383=GO_REF:0000024, GO:0030496=PMID:20208530, GO:0003777=GO_REF:0000024, GO:0006886=PMID:20208530, GO:0005524=GO_REF:0000037, GO:0032588=GO_REF:0000024, GO:0000910=PMID:20208530, GO:0007049=GO_REF:0000037, GO:0000139=GO_REF:0000039, GO:0010008=PMID:19841138, GO:0007018=GO_REF:0000002} Q9H1H9 Kinesin-like protein KIF13A protein 20110317 {GO:0005515=IPI, GO:0005813=IDA, GO:0035459=IMP, GO:0043001=ISS, GO:0005875=IEA, GO:0032438=IMP, GO:0005874=IEA, GO:0008333=IMP, GO:0072383=ISS, GO:0030496=IDA, GO:0003777=ISS, GO:0006886=IMP, GO:0005524=IEA, GO:0032588=ISS, GO:0000910=IMP, GO:0007049=IEA, GO:0000139=IEA, GO:0010008=IDA, GO:0007018=IEA} Golgi to plasma membrane protein transport, cargo loading into vesicle, cell cycle, cytokinesis, endosome to lysosome transport, intracellular protein transport, melanosome organization, microtubule-based movement, plus-end-directed vesicle transport along microtubule Golgi membrane, centrosome, endosome membrane, microtubule, microtubule associated complex, midbody, trans-Golgi network membrane ATP binding, microtubule motor activity, protein binding Human UniProtKB:Q9EQW7 KIF13B IntAct UniProtKB {GO:0005515=PMID:10859302, GO:0030424=PMID:20194617, GO:0019901=PMID:20194617, GO:0005875=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0006605=PMID:10859302, GO:0003777=PMID:10859302, GO:0005524=GO_REF:0000037, GO:0007165=PMID:10859302, GO:0071889=PMID:20194617, GO:0005737=PMID:10859302, GO:0042110=PMID:12496241, GO:0050770=PMID:20194617, GO:0007018=PMID:10859302} Q9NQT8 Kinesin-like protein KIF13B protein 20130415 {GO:0005515=IPI, GO:0030424=IDA, GO:0019901=IPI, GO:0005875=IEA, GO:0005874=IEA, GO:0006605=TAS, GO:0003777=NAS, GO:0005524=IEA, GO:0007165=NAS, GO:0071889=IDA, GO:0005737=IDA, GO:0042110=NAS, GO:0050770=IDA, GO:0007018=TAS} T cell activation, microtubule-based movement, protein targeting, regulation of axonogenesis, signal transduction axon, cytoplasm, microtubule, microtubule associated complex 14-3-3 protein binding, ATP binding, microtubule motor activity, protein binding, protein kinase binding Human UniProtKB:Q12959-2 KIF14 UniProtKB UniProtKB {GO:0005515=PMID:16820410, GO:0005737=GO_REF:0000039, GO:0005875=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0005819=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0003777=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0007018=GO_REF:0000002} Q15058 Kinesin-like protein KIF14 protein 20091203 {GO:0005515=IPI, GO:0005737=IEA, GO:0005875=IEA, GO:0005874=IEA, GO:0005819=IEA, GO:0005634=IEA, GO:0003777=IEA, GO:0005524=IEA, GO:0007018=IEA} microtubule-based movement cytoplasm, microtubule, microtubule associated complex, nucleus, spindle ATP binding, microtubule motor activity, protein binding Human UniProtKB:P32121 KIF15 Reactome UniProtKB {GO:0005813=PMID:10878014, GO:0005873=PMID:10878014, GO:0008283=PMID:10878014, GO:0005875=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0005819=GO_REF:0000039, GO:0003777=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0003677=PMID:10878014, GO:0005829=Reactome:REACT_120995, GO:0019886=Reactome:REACT_121399, GO:0003774=PMID:10878014, GO:0007067=PMID:10878014, GO:0007596=Reactome:REACT_604, GO:0007018=Reactome:REACT_25201} Q9NS87 Kinesin-like protein KIF15 protein 20130301 {GO:0005813=TAS, GO:0005873=TAS, GO:0008283=TAS, GO:0005875=IEA, GO:0005874=IEA, GO:0005819=IEA, GO:0003777=IEA, GO:0005524=IEA, GO:0003677=TAS, GO:0005829=TAS, GO:0019886=TAS, GO:0003774=TAS, GO:0007067=TAS, GO:0007596=TAS, GO:0007018=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, blood coagulation, cell proliferation, microtubule-based movement, mitosis centrosome, cytosol, microtubule, microtubule associated complex, plus-end kinesin complex, spindle ATP binding, DNA binding, microtubule motor activity, motor activity Human KIF16B UniProtKB UniProtKB {GO:0001704=GO_REF:0000024, GO:0017137=GO_REF:0000019, GO:0005875=GO_REF:0000002, GO:0043325=PMID:17641687, GO:0005874=GO_REF:0000037, GO:0080025=PMID:17641687, GO:0005547=PMID:17641687, GO:0032266=PMID:15882625, GO:0045022=PMID:15882625, GO:0006895=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0001919=PMID:15882625, GO:0007154=GO_REF:0000002, GO:0007492=GO_REF:0000024, GO:0007173=PMID:15882625, GO:0008543=GO_REF:0000024, GO:0032801=PMID:15882625, GO:0031901=GO_REF:0000039, GO:0008574=PMID:15882625, GO:0035091=GO_REF:0000002, GO:0005769=PMID:15882625, GO:0005768=PMID:17641687, GO:0007018=GO_REF:0000002} Q96L93 Kinesin-like protein KIF16B protein 20110415 {GO:0001704=ISS, GO:0017137=IEA, GO:0005875=IEA, GO:0043325=IDA, GO:0005874=IEA, GO:0080025=IDA, GO:0005547=IDA, GO:0032266=IDA, GO:0045022=IMP, GO:0006895=ISS, GO:0005524=IEA, GO:0001919=IMP, GO:0007154=IEA, GO:0007492=ISS, GO:0007173=IMP, GO:0008543=ISS, GO:0032801=IMP, GO:0031901=IEA, GO:0008574=IDA, GO:0035091=IEA, GO:0005769=IDA, GO:0005768=IDA, GO:0007018=IEA} Golgi to endosome transport, cell communication, early endosome to late endosome transport, endoderm development, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, formation of primary germ layer, microtubule-based movement, receptor catabolic process, regulation of receptor recycling early endosome, early endosome membrane, endosome, microtubule, microtubule associated complex ATP binding, Rab GTPase binding, phosphatidylinositol binding, phosphatidylinositol-3,4,5-trisphosphate binding, phosphatidylinositol-3,4-bisphosphate binding, phosphatidylinositol-3,5-bisphosphate binding, phosphatidylinositol-3-phosphate binding, plus-end-directed microtubule motor activity Human UniProtKB:B1AVY7 KIF17 ENSEMBL UniProtKB {GO:0005871=GO_REF:0000019, GO:0005737=GO_REF:0000037, GO:0031503=GO_REF:0000019, GO:0005874=GO_REF:0000037, GO:0016192=GO_REF:0000019, GO:0003777=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0007018=GO_REF:0000002} Q9P2E2 Kinesin-like protein KIF17 protein 20130413 {GO:0005871=IEA, GO:0005737=IEA, GO:0031503=IEA, GO:0005874=IEA, GO:0016192=IEA, GO:0003777=IEA, GO:0015031=IEA, GO:0005524=IEA, GO:0007018=IEA} microtubule-based movement, protein complex localization, protein transport, vesicle-mediated transport cytoplasm, kinesin complex, microtubule ATP binding, microtubule motor activity Human Ensembl:ENSMUSP00000030539 KIF18A HPA UniProtKB {GO:0008017=PMID:18680169, GO:0005828=PMID:17346968, GO:0005515=PMID:17006958, GO:0043130=PMID:18680169, GO:0000236=Reactome:REACT_682, GO:0005634=PMID:18680169, GO:0015031=GO_REF:0000037, GO:0070463=PMID:17346968, GO:0005829=Reactome:REACT_150414, GO:0019886=Reactome:REACT_121399, GO:0005737=GO_REF:0000052, GO:0051010=PMID:17346968, GO:0008574=PMID:17346968, GO:0015630=GO_REF:0000052, GO:0000087=Reactome:REACT_910, GO:0007019=PMID:17346968, GO:0007018=Reactome:REACT_25201, GO:0005815=GO_REF:0000039, GO:0005875=GO_REF:0000002, GO:0003779=PMID:18680169, GO:0005524=GO_REF:0000037, GO:0001726=PMID:17006958, GO:0007596=Reactome:REACT_604, GO:0005901=PMID:17006958, GO:0007080=PMID:17346968, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} Q8NI77 Kinesin-like protein KIF18A protein 20111111 {GO:0008017=IDA, GO:0005828=IDA, GO:0005515=IPI, GO:0043130=IDA, GO:0000236=TAS, GO:0005634=IDA, GO:0015031=IEA, GO:0070463=IDA, GO:0005829=TAS, GO:0019886=TAS, GO:0005737=IDA, GO:0051010=IDA, GO:0008574=IDA, GO:0015630=IDA, GO:0000087=TAS, GO:0007019=IDA, GO:0007018=TAS, GO:0005815=IEA, GO:0005875=IEA, GO:0003779=IPI, GO:0005524=IEA, GO:0001726=IDA, GO:0007596=TAS, GO:0005901=IDA, GO:0007080=IDA, GO:0000278=TAS, GO:0000090=TAS} M phase of mitotic cell cycle, antigen processing and presentation of exogenous peptide antigen via MHC class II, blood coagulation, microtubule depolymerization, microtubule-based movement, mitotic anaphase, mitotic cell cycle, mitotic metaphase plate congression, mitotic prometaphase, protein transport caveola, cytoplasm, cytosol, kinetochore microtubule, microtubule associated complex, microtubule cytoskeleton, microtubule organizing center, nucleus, ruffle ATP binding, actin binding, microtubule binding, microtubule plus-end binding, plus-end-directed microtubule motor activity, protein binding, tubulin-dependent ATPase activity, ubiquitin binding Human KIF18B HPA UniProtKB {GO:0005886=GO_REF:0000052, GO:0005875=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003777=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0007067=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0000278=PMID:20600703, GO:0051302=PMID:20600703, GO:0007018=GO_REF:0000002, GO:0051301=GO_REF:0000037} Q86Y91 Kinesin-like protein KIF18B protein 20110516 {GO:0005886=IDA, GO:0005875=IEA, GO:0005874=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003777=IEA, GO:0005524=IEA, GO:0007067=IEA, GO:0005737=IDA, GO:0000278=IDA, GO:0051302=IDA, GO:0007018=IEA, GO:0051301=IEA} cell division, microtubule-based movement, mitosis, mitotic cell cycle, regulation of cell division cytoplasm, microtubule, microtubule associated complex, nucleolus, nucleus, plasma membrane ATP binding, microtubule motor activity Human KIF1A HPA UniProtKB {GO:0008219=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0003774=PMID:7539720, GO:0005543=GO_REF:0000002, GO:0005875=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0008089=PMID:7539720, GO:0003777=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0007018=GO_REF:0000002} Q12756 Kinesin-like protein KIF1A protein 20101115 {GO:0008219=IEA, GO:0005737=IDA, GO:0003774=TAS, GO:0005543=IEA, GO:0005875=IEA, GO:0005874=IEA, GO:0005634=IDA, GO:0008089=TAS, GO:0003777=IEA, GO:0005524=IEA, GO:0007018=IEA} anterograde axon cargo transport, cell death, microtubule-based movement cytoplasm, microtubule, microtubule associated complex, nucleus ATP binding, microtubule motor activity, motor activity, phospholipid binding Human KIF1B UniProtKB UniProtKB {GO:0005515=PMID:16225668, GO:0043005=GO_REF:0000024, GO:0005875=GO_REF:0000024, GO:0005874=GO_REF:0000037, GO:0006915=GO_REF:0000037, GO:0031410=GO_REF:0000024, GO:0007274=GO_REF:0000024, GO:0003777=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0007270=GO_REF:0000024, GO:0005739=GO_REF:0000039, GO:0030705=GO_REF:0000024, GO:0005543=GO_REF:0000002, GO:0047497=GO_REF:0000019, GO:0019894=PMID:10341097, GO:0008089=GO_REF:0000024, GO:0016887=GO_REF:0000024, GO:0030659=GO_REF:0000024, GO:0007018=GO_REF:0000024} O60333 Kinesin-like protein KIF1B protein 20120611 {GO:0005515=IPI, GO:0043005=ISS, GO:0005875=ISS, GO:0005874=IEA, GO:0006915=IEA, GO:0031410=ISS, GO:0007274=ISS, GO:0003777=ISS, GO:0005524=IEA, GO:0007270=ISS, GO:0005739=IEA, GO:0030705=ISS, GO:0005543=IEA, GO:0047497=IEA, GO:0019894=TAS, GO:0008089=ISS, GO:0016887=ISS, GO:0030659=ISS, GO:0007018=ISS} anterograde axon cargo transport, apoptotic process, cytoskeleton-dependent intracellular transport, microtubule-based movement, mitochondrion transport along microtubule, neuromuscular synaptic transmission, neuron-neuron synaptic transmission cytoplasmic vesicle, cytoplasmic vesicle membrane, microtubule, microtubule associated complex, mitochondrion, neuron projection ATP binding, ATPase activity, kinesin binding, microtubule motor activity, phospholipid binding, protein binding Human UniProtKB:O88658 KIF1C PINC UniProtKB {GO:0003774=PMID:9685376, GO:0005794=GO_REF:0000019, GO:0005783=PMID:9685376, GO:0006890=GO_REF:0000019, GO:0005875=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0003777=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0007018=GO_REF:0000002} O43896 Kinesin-like protein KIF1C protein 20030904 {GO:0003774=TAS, GO:0005794=IEA, GO:0005783=TAS, GO:0006890=IEA, GO:0005875=IEA, GO:0005874=IEA, GO:0003777=IEA, GO:0005524=IEA, GO:0007018=IEA} microtubule-based movement, retrograde vesicle-mediated transport, Golgi to ER Golgi apparatus, endoplasmic reticulum, microtubule, microtubule associated complex ATP binding, microtubule motor activity, motor activity Human KIF20A Reactome UniProtKB {GO:0005215=PMID:9438855, GO:0005794=GO_REF:0000039, GO:0019901=PMID:12939256, GO:0005875=GO_REF:0000002, GO:0001578=PMID:12939256, GO:0005874=GO_REF:0000037, GO:0005819=PMID:12939256, GO:0003777=GO_REF:0000002, GO:0015031=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0000910=Reactome:REACT_1932, GO:0000087=Reactome:REACT_910, GO:0005654=Reactome:REACT_1120, GO:0000278=Reactome:REACT_152, GO:0016192=PMID:9438855, GO:0007018=GO_REF:0000002} O95235 Kinesin-like protein KIF20A protein 20130213 {GO:0005215=TAS, GO:0005794=IEA, GO:0019901=IPI, GO:0005875=IEA, GO:0001578=IDA, GO:0005874=IEA, GO:0005819=IDA, GO:0003777=IEA, GO:0015031=IEA, GO:0005524=IEA, GO:0000910=TAS, GO:0000087=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0016192=TAS, GO:0007018=IEA} M phase of mitotic cell cycle, cytokinesis, microtubule bundle formation, microtubule-based movement, mitotic cell cycle, protein transport, vesicle-mediated transport Golgi apparatus, microtubule, microtubule associated complex, nucleoplasm, spindle ATP binding, microtubule motor activity, protein kinase binding, transporter activity Human KIF20B GOC UniProtKB {GO:0007088=PMID:11470801, GO:0005813=PMID:11470801, GO:0006200=PMID:11470801, GO:0050699=PMID:11470801, GO:0005875=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0005819=GO_REF:0000039, GO:0005730=PMID:11470801, GO:0003777=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0007067=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0000087=PMID:8885239, GO:0005654=PMID:11470801, GO:0007050=PMID:11470801, GO:0016887=PMID:11470801, GO:0007018=GO_REF:0000002, GO:0051301=GO_REF:0000037} Q96Q89 Kinesin-like protein KIF20B protein 20130413 {GO:0007088=NAS, GO:0005813=IDA, GO:0006200=IDA, GO:0050699=IPI, GO:0005875=IEA, GO:0005874=IEA, GO:0005819=IEA, GO:0005730=IDA, GO:0003777=IEA, GO:0005524=IEA, GO:0007067=IEA, GO:0005737=IEA, GO:0000087=TAS, GO:0005654=IDA, GO:0007050=NAS, GO:0016887=IDA, GO:0007018=IEA, GO:0051301=IEA} ATP catabolic process, M phase of mitotic cell cycle, cell cycle arrest, cell division, microtubule-based movement, mitosis, regulation of mitosis centrosome, cytoplasm, microtubule, microtubule associated complex, nucleolus, nucleoplasm, spindle ATP binding, ATPase activity, WW domain binding, microtubule motor activity Human KIF21A IntAct UniProtKB {GO:0005515=PMID:19559006, GO:0005737=GO_REF:0000037, GO:0005875=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0003777=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0007018=GO_REF:0000002} Q7Z4S6 Kinesin-like protein KIF21A protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0005875=IEA, GO:0005874=IEA, GO:0003777=IEA, GO:0005524=IEA, GO:0007018=IEA} microtubule-based movement cytoplasm, microtubule, microtubule associated complex ATP binding, microtubule motor activity, protein binding Human UniProtKB:Q14678-2 KIF21B UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0005875=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0003777=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0007018=GO_REF:0000002} O75037 Kinesin-like protein KIF21B protein 20130413 {GO:0005737=IEA, GO:0005875=IEA, GO:0005874=IEA, GO:0003777=IEA, GO:0005524=IEA, GO:0007018=IEA} microtubule-based movement cytoplasm, microtubule, microtubule associated complex ATP binding, microtubule motor activity Human UniProtKB-KW:KW-0493 KIF22 HPA UniProtKB {GO:0005875=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0005819=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0003777=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_120995, GO:0019886=Reactome:REACT_121399, GO:0005737=GO_REF:0000052, GO:0007067=PMID:8599929, GO:0006281=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0000776=PMID:8599929, GO:0005925=GO_REF:0000052, GO:0000785=GO_REF:0000019, GO:0007018=Reactome:REACT_25201} Q14807 Kinesin-like protein KIF22 protein 20111111 {GO:0005875=IEA, GO:0005874=IEA, GO:0005819=IEA, GO:0005634=IDA, GO:0003777=IEA, GO:0003677=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0019886=TAS, GO:0005737=IDA, GO:0007067=TAS, GO:0006281=IEA, GO:0007596=TAS, GO:0000776=TAS, GO:0005925=IDA, GO:0000785=IEA, GO:0007018=TAS} DNA repair, antigen processing and presentation of exogenous peptide antigen via MHC class II, blood coagulation, microtubule-based movement, mitosis chromatin, cytoplasm, cytosol, focal adhesion, kinetochore, microtubule, microtubule associated complex, nucleus, spindle ATP binding, DNA binding, microtubule motor activity Human KIF23 IntAct UniProtKB {GO:0051256=PMID:16103226, GO:0005515=PMID:18329369, GO:0008017=PMID:11782313, GO:0072686=PMID:16236794, GO:0005813=PMID:20186884, GO:0005871=PMID:1406973, GO:0000022=PMID:1406973, GO:0005875=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0005819=PMID:15197175, GO:0030496=PMID:20186884, GO:0005634=PMID:11782313, GO:0003777=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_120995, GO:0045171=GO_REF:0000019, GO:0019886=Reactome:REACT_121399, GO:0000910=Reactome:REACT_1932, GO:0007596=Reactome:REACT_604, GO:0000087=Reactome:REACT_910, GO:0005654=Reactome:REACT_1930, GO:0097149=PMID:16236794, GO:0000278=Reactome:REACT_152, GO:0007018=Reactome:REACT_25201} Q02241 Kinesin-like protein KIF23 protein 20130415 {GO:0051256=IMP, GO:0005515=IPI, GO:0008017=IDA, GO:0072686=IDA, GO:0005813=IDA, GO:0005871=TAS, GO:0000022=TAS, GO:0005875=IEA, GO:0005874=IEA, GO:0005819=IDA, GO:0030496=IDA, GO:0005634=IDA, GO:0003777=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0045171=IEA, GO:0019886=TAS, GO:0000910=TAS, GO:0007596=TAS, GO:0000087=TAS, GO:0005654=TAS, GO:0097149=IDA, GO:0000278=TAS, GO:0007018=TAS} M phase of mitotic cell cycle, antigen processing and presentation of exogenous peptide antigen via MHC class II, blood coagulation, cytokinesis, microtubule-based movement, mitotic cell cycle, mitotic spindle elongation, spindle midzone assembly involved in mitosis centralspindlin complex, centrosome, cytosol, intercellular bridge, kinesin complex, microtubule, microtubule associated complex, midbody, mitotic spindle, nucleoplasm, nucleus, spindle ATP binding, microtubule binding, microtubule motor activity, protein binding Human UniProtKB:Q9NR09 KIF24 IntAct UniProtKB {GO:0005515=PMID:21620453, GO:0042384=PMID:21620453, GO:0005814=PMID:21620453, GO:0005875=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0003777=PMID:21620453, GO:0005524=GO_REF:0000037, GO:0007019=PMID:21620453, GO:0007018=GO_REF:0000002} Q5T7B8 Kinesin-like protein KIF24 protein 20130415 {GO:0005515=IPI, GO:0042384=IMP, GO:0005814=IDA, GO:0005875=IEA, GO:0005874=IEA, GO:0003777=IDA, GO:0005524=IEA, GO:0007019=IDA, GO:0007018=IEA} cilium assembly, microtubule depolymerization, microtubule-based movement centriole, microtubule, microtubule associated complex ATP binding, microtubule motor activity, protein binding Human UniProtKB:Q8IW35 KIF26A Reactome UniProtKB {GO:0008017=GO_REF:0000024, GO:0005875=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0003777=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0048484=GO_REF:0000024, GO:0005829=Reactome:REACT_120995, GO:0019886=Reactome:REACT_121399, GO:0001560=GO_REF:0000024, GO:0007596=Reactome:REACT_604, GO:0009968=GO_REF:0000024, GO:0016887=GO_REF:0000024, GO:0007018=Reactome:REACT_25201} Q9ULI4 Kinesin-like protein KIF26A protein 20130301 {GO:0008017=ISS, GO:0005875=IEA, GO:0005874=IEA, GO:0003777=ISS, GO:0005524=IEA, GO:0048484=ISS, GO:0005829=TAS, GO:0019886=TAS, GO:0001560=ISS, GO:0007596=TAS, GO:0009968=ISS, GO:0016887=ISS, GO:0007018=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, blood coagulation, enteric nervous system development, microtubule-based movement, negative regulation of signal transduction, regulation of cell growth by extracellular stimulus cytosol, microtubule, microtubule associated complex ATP binding, ATPase activity, microtubule binding, microtubule motor activity Human KIF26B UniProtKB UniProtKB {GO:0072092=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0022409=GO_REF:0000019, GO:0005875=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0030010=GO_REF:0000019, GO:0003777=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0007018=GO_REF:0000002} Q2KJY2 Kinesin-like protein KIF26B protein 20130413 {GO:0072092=IEA, GO:0005737=IEA, GO:0022409=IEA, GO:0005875=IEA, GO:0005874=IEA, GO:0030010=IEA, GO:0003777=IEA, GO:0005524=IEA, GO:0007018=IEA} establishment of cell polarity, microtubule-based movement, positive regulation of cell-cell adhesion, ureteric bud invasion cytoplasm, microtubule, microtubule associated complex ATP binding, microtubule motor activity Human UniProtKB-SubCell:SL-0086 KIF2A Reactome UniProtKB {GO:0005515=PMID:18411309, GO:0000236=Reactome:REACT_682, GO:0005813=PMID:21399614, GO:0005875=GO_REF:0000002, GO:0005874=GO_REF:0000038, GO:0003777=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0005829=Reactome:REACT_150414, GO:0007399=GO_REF:0000037, GO:0019886=Reactome:REACT_121399, GO:0003774=PMID:9177777, GO:0000922=PMID:18411309, GO:0007596=Reactome:REACT_604, GO:0000087=Reactome:REACT_910, GO:0005876=PMID:18411309, GO:0000278=Reactome:REACT_152, GO:0007052=PMID:18411309, GO:0000090=Reactome:REACT_1275, GO:0007018=Reactome:REACT_25201, GO:0051301=GO_REF:0000037} O00139 Kinesin-like protein KIF2A protein 20130301 {GO:0005515=IPI, GO:0000236=TAS, GO:0005813=IDA, GO:0005875=IEA, GO:0005874=IEA, GO:0003777=IEA, GO:0005524=IEA, GO:0030154=IEA, GO:0005829=TAS, GO:0007399=IEA, GO:0019886=TAS, GO:0003774=TAS, GO:0000922=IDA, GO:0007596=TAS, GO:0000087=TAS, GO:0005876=IDA, GO:0000278=TAS, GO:0007052=IDA, GO:0000090=TAS, GO:0007018=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, antigen processing and presentation of exogenous peptide antigen via MHC class II, blood coagulation, cell differentiation, cell division, microtubule-based movement, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, mitotic spindle organization, nervous system development centrosome, cytosol, microtubule, microtubule associated complex, spindle microtubule, spindle pole ATP binding, microtubule motor activity, motor activity, protein binding Human KIF2B HPA UniProtKB {GO:0000236=Reactome:REACT_682, GO:0005815=GO_REF:0000039, GO:0005875=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005819=GO_REF:0000039, GO:0051983=PMID:19060894, GO:0005634=GO_REF:0000052, GO:0003777=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_150414, GO:0019886=Reactome:REACT_121399, GO:0007596=Reactome:REACT_604, GO:0015630=GO_REF:0000052, GO:0000087=Reactome:REACT_910, GO:0000777=GO_REF:0000039, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0007019=PMID:19060894, GO:0007018=Reactome:REACT_25201, GO:0051301=GO_REF:0000037} Q8N4N8 Kinesin-like protein KIF2B protein 20100326 {GO:0000236=TAS, GO:0005815=IEA, GO:0005875=IEA, GO:0005874=IEA, GO:0005730=IDA, GO:0005819=IEA, GO:0051983=IMP, GO:0005634=IDA, GO:0003777=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0019886=TAS, GO:0007596=TAS, GO:0015630=IDA, GO:0000087=TAS, GO:0000777=IEA, GO:0000278=TAS, GO:0000090=TAS, GO:0007019=IMP, GO:0007018=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, antigen processing and presentation of exogenous peptide antigen via MHC class II, blood coagulation, cell division, microtubule depolymerization, microtubule-based movement, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, regulation of chromosome segregation condensed chromosome kinetochore, cytosol, microtubule, microtubule associated complex, microtubule cytoskeleton, microtubule organizing center, nucleolus, nucleus, spindle ATP binding, microtubule motor activity Human KIF2C Reactome UniProtKB {GO:0005515=PMID:19632184, GO:0005881=GO_REF:0000024, GO:0000236=Reactome:REACT_682, GO:0008283=PMID:9434124, GO:0005634=GO_REF:0000039, GO:0005829=Reactome:REACT_150414, GO:0019886=Reactome:REACT_121399, GO:0007059=GO_REF:0000037, GO:0051010=PMID:19632184, GO:0015630=GO_REF:0000054, GO:0000087=Reactome:REACT_910, GO:0007019=PMID:19060894, GO:0007018=Reactome:REACT_25201, GO:0005871=PMID:9434124, GO:0005875=GO_REF:0000002, GO:0005874=GO_REF:0000038, GO:0030951=PMID:14718566, GO:0051983=PMID:19060894, GO:0019237=PMID:9434124, GO:0003777=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0007067=PMID:9434124, GO:0007596=Reactome:REACT_604, GO:0000777=GO_REF:0000039, GO:0000776=PMID:14960279, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0000775=PMID:14960279, GO:0051301=GO_REF:0000037} Q99661 Kinesin-like protein KIF2C protein 20130301 {GO:0005515=IPI, GO:0005881=ISS, GO:0000236=TAS, GO:0008283=TAS, GO:0005634=IEA, GO:0005829=TAS, GO:0019886=TAS, GO:0007059=IEA, GO:0051010=IDA, GO:0015630=IDA, GO:0000087=TAS, GO:0007019=IMP, GO:0007018=TAS, GO:0005871=TAS, GO:0005875=IEA, GO:0005874=IEA, GO:0030951=IMP, GO:0051983=IMP, GO:0019237=TAS, GO:0003777=IEA, GO:0005524=IEA, GO:0007067=TAS, GO:0007596=TAS, GO:0000777=IEA, GO:0000776=IDA, GO:0000278=TAS, GO:0000090=TAS, GO:0000775=IDA, GO:0051301=IEA} M phase of mitotic cell cycle, antigen processing and presentation of exogenous peptide antigen via MHC class II, blood coagulation, cell division, cell proliferation, chromosome segregation, establishment or maintenance of microtubule cytoskeleton polarity, microtubule depolymerization, microtubule-based movement, mitosis, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, regulation of chromosome segregation chromosome, centromeric region, condensed chromosome kinetochore, cytoplasmic microtubule, cytosol, kinesin complex, kinetochore, microtubule, microtubule associated complex, microtubule cytoskeleton, nucleus ATP binding, centromeric DNA binding, microtubule motor activity, microtubule plus-end binding, protein binding Human KIF3A BHF-UCL UniProtKB {GO:0005515=PMID:16298999, GO:0007368=GO_REF:0000019, GO:0016939=PMID:16298999, GO:0072383=PMID:16298999, GO:0009952=GO_REF:0000019, GO:0007224=GO_REF:0000019, GO:0005829=Reactome:REACT_120995, GO:0007507=GO_REF:0000019, GO:0019886=Reactome:REACT_121399, GO:0008574=PMID:16298999, GO:0021904=GO_REF:0000019, GO:0005876=PMID:16298999, GO:0007018=Reactome:REACT_25201, GO:0005813=PMID:16298999, GO:0006996=PMID:1447303, GO:0001822=GO_REF:0000019, GO:0005875=GO_REF:0000002, GO:0005874=GO_REF:0000038, GO:0072372=GO_REF:0000024, GO:0003777=GO_REF:0000002, GO:0001701=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0042384=GO_REF:0000024, GO:0007596=Reactome:REACT_604, GO:0032391=GO_REF:0000019, GO:0016044=Reactome:REACT_11123} Q9Y496 Kinesin-like protein KIF3A protein 20110117 {GO:0005515=IPI, GO:0007368=IEA, GO:0016939=IDA, GO:0072383=TAS, GO:0009952=IEA, GO:0007224=IEA, GO:0005829=TAS, GO:0007507=IEA, GO:0019886=TAS, GO:0008574=TAS, GO:0021904=IEA, GO:0005876=IDA, GO:0007018=TAS, GO:0005813=IDA, GO:0006996=TAS, GO:0001822=IEA, GO:0005875=IEA, GO:0005874=IEA, GO:0072372=ISS, GO:0003777=IEA, GO:0001701=IEA, GO:0005524=IEA, GO:0042384=ISS, GO:0007596=TAS, GO:0032391=IEA, GO:0016044=TAS} anterior/posterior pattern specification, antigen processing and presentation of exogenous peptide antigen via MHC class II, blood coagulation, cellular membrane organization, cilium assembly, determination of left/right symmetry, dorsal/ventral neural tube patterning, heart development, in utero embryonic development, kidney development, microtubule-based movement, organelle organization, plus-end-directed vesicle transport along microtubule, smoothened signaling pathway centrosome, cytosol, kinesin II complex, microtubule, microtubule associated complex, photoreceptor connecting cilium, primary cilium, spindle microtubule ATP binding, microtubule motor activity, plus-end-directed microtubule motor activity, protein binding Human KIF3B BHF-UCL UniProtKB {GO:0005515=PMID:16298999, GO:0005813=PMID:16298999, GO:0007368=PMID:9865700, GO:0007100=PMID:16298999, GO:0005873=PMID:7559760, GO:0016939=PMID:16298999, GO:0005875=GO_REF:0000002, GO:0072383=PMID:16298999, GO:0003777=PMID:9865700, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_120995, GO:0019886=Reactome:REACT_121399, GO:0007596=Reactome:REACT_604, GO:0008574=PMID:7559760, GO:0017048=PMID:19635168, GO:0005876=PMID:16298999, GO:0090307=PMID:19635168, GO:0008089=PMID:7559760, GO:0007052=PMID:16298999, GO:0016044=Reactome:REACT_11123, GO:0007018=Reactome:REACT_25201} O15066 Kinesin-like protein KIF3B protein 20110117 {GO:0005515=IPI, GO:0005813=NAS, GO:0007368=TAS, GO:0007100=TAS, GO:0005873=TAS, GO:0016939=IDA, GO:0005875=IEA, GO:0072383=TAS, GO:0003777=TAS, GO:0005524=IEA, GO:0005829=TAS, GO:0019886=TAS, GO:0007596=TAS, GO:0008574=TAS, GO:0017048=IPI, GO:0005876=NAS, GO:0090307=IMP, GO:0008089=TAS, GO:0007052=TAS, GO:0016044=TAS, GO:0007018=TAS} anterograde axon cargo transport, antigen processing and presentation of exogenous peptide antigen via MHC class II, blood coagulation, cellular membrane organization, determination of left/right symmetry, microtubule-based movement, mitotic centrosome separation, mitotic spindle organization, plus-end-directed vesicle transport along microtubule, spindle assembly involved in mitosis centrosome, cytosol, kinesin II complex, microtubule associated complex, plus-end kinesin complex, spindle microtubule ATP binding, Rho GTPase binding, microtubule motor activity, plus-end-directed microtubule motor activity, protein binding Human KIF3C Reactome UniProtKB {GO:0019886=Reactome:REACT_121399, GO:0003774=PMID:9480755, GO:0005871=PMID:9480755, GO:0007596=Reactome:REACT_604, GO:0005875=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0003777=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_120995, GO:0007018=Reactome:REACT_25201} O14782 Kinesin-like protein KIF3C protein 20130301 {GO:0019886=TAS, GO:0003774=TAS, GO:0005871=TAS, GO:0007596=TAS, GO:0005875=IEA, GO:0005874=IEA, GO:0003777=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0007018=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, blood coagulation, microtubule-based movement cytosol, kinesin complex, microtubule, microtubule associated complex ATP binding, microtubule motor activity, motor activity Human KIF4A HPA UniProtKB {GO:0006996=PMID:7929562, GO:0005694=GO_REF:0000039, GO:0005875=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0030496=PMID:15166316, GO:0005634=GO_REF:0000052, GO:0003777=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0016363=GO_REF:0000039, GO:0005829=Reactome:REACT_120995, GO:0019886=Reactome:REACT_121399, GO:0005737=PMID:7929562, GO:0007596=Reactome:REACT_604, GO:0007411=Reactome:REACT_18266, GO:0005876=PMID:7929562, GO:0008089=PMID:7929562, GO:0007018=Reactome:REACT_25201} O95239 Chromosome-associated kinesin KIF4A protein 20120912 {GO:0006996=TAS, GO:0005694=IEA, GO:0005875=IEA, GO:0005730=IDA, GO:0030496=IDA, GO:0005634=IDA, GO:0003777=IEA, GO:0003677=IEA, GO:0005524=IEA, GO:0016363=IEA, GO:0005829=TAS, GO:0019886=TAS, GO:0005737=TAS, GO:0007596=TAS, GO:0007411=TAS, GO:0005876=TAS, GO:0008089=TAS, GO:0007018=TAS} anterograde axon cargo transport, antigen processing and presentation of exogenous peptide antigen via MHC class II, axon guidance, blood coagulation, microtubule-based movement, organelle organization chromosome, cytoplasm, cytosol, microtubule associated complex, midbody, nuclear matrix, nucleolus, nucleus, spindle microtubule ATP binding, DNA binding, microtubule motor activity NOT Human KIF4B HPA UniProtKB {GO:0005694=GO_REF:0000002, GO:0005875=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003777=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0016363=GO_REF:0000039, GO:0005829=Reactome:REACT_120995, GO:0019886=Reactome:REACT_121399, GO:0007411=Reactome:REACT_18266, GO:0007596=Reactome:REACT_604, GO:0007018=Reactome:REACT_25201} Q2VIQ3 Chromosome-associated kinesin KIF4B protein 20120912 {GO:0005694=IEA, GO:0005875=IEA, GO:0005874=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003777=IEA, GO:0003677=IEA, GO:0005524=IEA, GO:0016363=IEA, GO:0005829=TAS, GO:0019886=TAS, GO:0007411=TAS, GO:0007596=TAS, GO:0007018=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, axon guidance, blood coagulation, microtubule-based movement chromosome, cytosol, microtubule, microtubule associated complex, nuclear matrix, nucleolus, nucleus ATP binding, DNA binding, microtubule motor activity NOT Human KIF5A IntAct UniProtKB {GO:0005515=PMID:22705394, GO:0043005=GO_REF:0000019, GO:0008219=GO_REF:0000037, GO:0048471=GO_REF:0000039, GO:0005871=PMID:7514426, GO:0005875=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0007268=PMID:7514426, GO:0003777=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_120995, GO:0019886=Reactome:REACT_121399, GO:0005737=GO_REF:0000019, GO:0003774=PMID:7514426, GO:0016020=PMID:7514426, GO:0007596=Reactome:REACT_604, GO:0035253=GO_REF:0000019, GO:0007018=Reactome:REACT_25201} Q12840 Kinesin heavy chain isoform 5A protein 20130415 {GO:0005515=IPI, GO:0043005=IEA, GO:0008219=IEA, GO:0048471=IEA, GO:0005871=TAS, GO:0005875=IEA, GO:0005874=IEA, GO:0007268=TAS, GO:0003777=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0019886=TAS, GO:0005737=IEA, GO:0003774=TAS, GO:0016020=TAS, GO:0007596=TAS, GO:0035253=IEA, GO:0007018=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, blood coagulation, cell death, microtubule-based movement, synaptic transmission ciliary rootlet, cytoplasm, cytosol, kinesin complex, membrane, microtubule, microtubule associated complex, neuron projection, perinuclear region of cytoplasm ATP binding, microtubule motor activity, motor activity, protein binding Human UniProtKB:Q96NW4 KIF5B BHF-UCL UniProtKB {GO:0005515=PMID:19164528, GO:0008017=GO_REF:0000024, GO:0043005=GO_REF:0000019, GO:0005871=PMID:1607388, GO:0048471=GO_REF:0000024, GO:0005874=GO_REF:0000037, GO:0043268=PMID:19675065, GO:0003777=GO_REF:0000024, GO:0035617=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0031982=PMID:20682791, GO:0047496=GO_REF:0000024, GO:0035253=GO_REF:0000019, GO:0042391=PMID:19675065, GO:0044267=Reactome:REACT_17015, GO:0007028=GO_REF:0000019, GO:0007018=PMID:7514426} P33176 Kinesin-1 heavy chain protein 20120920 {GO:0005515=IPI, GO:0008017=ISS, GO:0043005=IEA, GO:0005871=TAS, GO:0048471=ISS, GO:0005874=IEA, GO:0043268=IDA, GO:0003777=ISS, GO:0035617=ISS, GO:0005524=IEA, GO:0031982=IDA, GO:0047496=ISS, GO:0035253=IEA, GO:0042391=IDA, GO:0044267=TAS, GO:0007028=IEA, GO:0007018=TAS} cellular protein metabolic process, cytoplasm organization, microtubule-based movement, positive regulation of potassium ion transport, regulation of membrane potential, stress granule disassembly, vesicle transport along microtubule ciliary rootlet, kinesin complex, microtubule, neuron projection, perinuclear region of cytoplasm, vesicle ATP binding, microtubule binding, microtubule motor activity, protein binding Human KIF5C IntAct UniProtKB {GO:0005515=PMID:19135897, GO:0043005=GO_REF:0000019, GO:0005871=PMID:9782088, GO:0006996=PMID:9782088, GO:0005875=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0003777=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0005737=GO_REF:0000019, GO:0008045=GO_REF:0000019, GO:0035253=GO_REF:0000019, GO:0051028=GO_REF:0000024, GO:0007018=GO_REF:0000002} O60282 Kinesin heavy chain isoform 5C protein 20130415 {GO:0005515=IPI, GO:0043005=IEA, GO:0005871=TAS, GO:0006996=TAS, GO:0005875=IEA, GO:0005874=IEA, GO:0003777=IEA, GO:0005524=IEA, GO:0005737=IEA, GO:0008045=IEA, GO:0035253=IEA, GO:0051028=ISS, GO:0007018=IEA} mRNA transport, microtubule-based movement, motor neuron axon guidance, organelle organization ciliary rootlet, cytoplasm, kinesin complex, microtubule, microtubule associated complex, neuron projection ATP binding, microtubule motor activity, protein binding Human UniProtKB:Q8IXI2 KIF6 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0005737=GO_REF:0000037, GO:0005875=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0003777=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0007018=GO_REF:0000002} Q6ZMV9 Kinesin-like protein KIF6 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0005875=IEA, GO:0005874=IEA, GO:0003777=IEA, GO:0005524=IEA, GO:0007018=IEA} microtubule-based movement cytoplasm, microtubule, microtubule associated complex ATP binding, microtubule motor activity, protein binding Human UniProtKB:Q92624 KIF7 UniProtKB UniProtKB {GO:0005515=PMID:21633164, GO:0005929=PMID:19592253, GO:0045880=GO_REF:0000024, GO:0005875=GO_REF:0000002, GO:0005874=GO_REF:0000038, GO:0045879=GO_REF:0000024, GO:0003777=PMID:21633164, GO:0005524=GO_REF:0000037, GO:0007018=GO_REF:0000002} Q2M1P5 Kinesin-like protein KIF7 protein 20110929 {GO:0005515=IPI, GO:0005929=IDA, GO:0045880=ISS, GO:0005875=IEA, GO:0005874=IEA, GO:0045879=ISS, GO:0003777=IDA, GO:0005524=IEA, GO:0007018=IEA} microtubule-based movement, negative regulation of smoothened signaling pathway, positive regulation of smoothened signaling pathway cilium, microtubule, microtubule associated complex ATP binding, microtubule motor activity, protein binding Human UniProtKB:O15259 KIFAP3 BHF-UCL UniProtKB {GO:0005515=PMID:9506951, GO:0000794=PMID:16298999, GO:0005813=PMID:16298999, GO:0005871=GO_REF:0000002, GO:0008285=GO_REF:0000019, GO:0016939=PMID:16298999, GO:0005783=PMID:8900189, GO:0072383=PMID:16298999, GO:0046587=GO_REF:0000019, GO:0005829=Reactome:REACT_120995, GO:0019886=Reactome:REACT_121399, GO:0007165=PMID:8900189, GO:0008104=GO_REF:0000019, GO:0006461=PMID:8900189, GO:0007596=Reactome:REACT_604, GO:0005876=PMID:16298999, GO:0019894=PMID:16298999, GO:0007017=GO_REF:0000024, GO:0016044=Reactome:REACT_11123, GO:0007018=Reactome:REACT_25201} Q92845 Kinesin-associated protein 3 protein 20110117 {GO:0005515=IPI, GO:0000794=IDA, GO:0005813=IDA, GO:0005871=IEA, GO:0008285=IEA, GO:0016939=IDA, GO:0005783=TAS, GO:0072383=TAS, GO:0046587=IEA, GO:0005829=TAS, GO:0019886=TAS, GO:0007165=TAS, GO:0008104=IEA, GO:0006461=TAS, GO:0007596=TAS, GO:0005876=IDA, GO:0019894=IPI, GO:0007017=ISS, GO:0016044=TAS, GO:0007018=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, blood coagulation, cellular membrane organization, microtubule-based movement, microtubule-based process, negative regulation of cell proliferation, plus-end-directed vesicle transport along microtubule, positive regulation of calcium-dependent cell-cell adhesion, protein complex assembly, protein localization, signal transduction centrosome, condensed nuclear chromosome, cytosol, endoplasmic reticulum, kinesin II complex, kinesin complex, spindle microtubule kinesin binding, protein binding Human KIFC1 Reactome UniProtKB {GO:0000070=PMID:8276466, GO:0005815=GO_REF:0000039, GO:0007596=Reactome:REACT_604, GO:0005875=GO_REF:0000029, GO:0005874=GO_REF:0000037, GO:0005819=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0003777=PMID:8276466, GO:0005524=PMID:8276466, GO:0005769=GO_REF:0000039, GO:0007018=Reactome:REACT_25201, GO:0051301=GO_REF:0000037} Q9BW19 Kinesin-like protein KIFC1 protein 20101103 {GO:0000070=NAS, GO:0005815=IEA, GO:0007596=TAS, GO:0005875=NAS, GO:0005874=IEA, GO:0005819=IEA, GO:0005634=IEA, GO:0003777=NAS, GO:0005524=NAS, GO:0005769=IEA, GO:0007018=TAS, GO:0051301=IEA} blood coagulation, cell division, microtubule-based movement, mitotic sister chromatid segregation early endosome, microtubule, microtubule associated complex, microtubule organizing center, nucleus, spindle ATP binding, microtubule motor activity Human KIFC2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0005875=GO_REF:0000002, GO:0005874=GO_REF:0000038, GO:0003777=GO_REF:0000002, GO:0005524=GO_REF:0000038, GO:0007018=GO_REF:0000002} Q96NN6 Kinesin family member C2, isoform CRA_a protein 20130413 {GO:0005737=IEA, GO:0005875=IEA, GO:0005874=IEA, GO:0003777=IEA, GO:0005524=IEA, GO:0007018=IEA} microtubule-based movement cytoplasm, microtubule, microtubule associated complex ATP binding, microtubule motor activity Human UniProtKB-KW:KW-0493 KIFC3 PINC UniProtKB {GO:0090136=PMID:19041755, GO:0005871=GO_REF:0000019, GO:0005813=PMID:19041755, GO:0005794=GO_REF:0000019, GO:0005875=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0003777=PMID:9782090, GO:0045218=PMID:19041755, GO:0005524=GO_REF:0000037, GO:0005915=PMID:19041755, GO:0008569=GO_REF:0000002, GO:0007030=GO_REF:0000019, GO:0007017=GO_REF:0000019, GO:0007601=PMID:9782090, GO:0030659=GO_REF:0000039, GO:0007018=GO_REF:0000002} Q9BVG8 Kinesin-like protein KIFC3 protein 20050308 {GO:0090136=IMP, GO:0005871=IEA, GO:0005813=IDA, GO:0005794=IEA, GO:0005875=IEA, GO:0005874=IEA, GO:0003777=TAS, GO:0045218=IMP, GO:0005524=IEA, GO:0005915=IDA, GO:0008569=IEA, GO:0007030=IEA, GO:0007017=IEA, GO:0007601=TAS, GO:0030659=IEA, GO:0007018=IEA} Golgi organization, epithelial cell-cell adhesion, microtubule-based movement, microtubule-based process, visual perception, zonula adherens maintenance Golgi apparatus, centrosome, cytoplasmic vesicle membrane, kinesin complex, microtubule, microtubule associated complex, zonula adherens ATP binding, microtubule motor activity, minus-end-directed microtubule motor activity Human KIN PINC UniProtKB {GO:0006397=PMID:17045609, GO:0003723=PMID:17045609, GO:0006310=GO_REF:0000037, GO:0005634=PMID:1923796, GO:0003677=PMID:1923796, GO:0046872=GO_REF:0000037, GO:0006974=PMID:12853634, GO:0016363=PMID:12754299, GO:0006260=PMID:12359749, GO:0005737=GO_REF:0000039, GO:0006281=GO_REF:0000037, GO:0003690=GO_REF:0000024, GO:0019048=GO_REF:0000037} O60870 DNA/RNA-binding protein KIN17 protein 20030904 {GO:0006397=TAS, GO:0003723=IDA, GO:0006310=IEA, GO:0005634=TAS, GO:0003677=TAS, GO:0046872=IEA, GO:0006974=IEP, GO:0016363=IDA, GO:0006260=IDA, GO:0005737=IEA, GO:0006281=IEA, GO:0003690=ISS, GO:0019048=IEA} DNA recombination, DNA repair, DNA replication, mRNA processing, response to DNA damage stimulus, virus-host interaction cytoplasm, nuclear matrix, nucleus DNA binding, RNA binding, double-stranded DNA binding, metal ion binding Human KIR2DL1 Reactome UniProtKB {GO:0005515=PMID:18604210, GO:0002769=PMID:18604210, GO:0006955=PMID:7749980, GO:0005886=Reactome:REACT_11140, GO:0005887=PMID:7749980, GO:0050776=Reactome:REACT_11152, GO:0004872=PMID:7749980} P43626 Killer cell immunoglobulin-like receptor 2DL1 protein 20070711 {GO:0005515=IPI, GO:0002769=IDA, GO:0006955=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0050776=TAS, GO:0004872=TAS} immune response, natural killer cell inhibitory signaling pathway, regulation of immune response integral to plasma membrane, plasma membrane protein binding, receptor activity Human KIR2DL3 Reactome UniProtKB {GO:0005515=PMID:18604210, GO:0006955=PMID:7749980, GO:0005886=Reactome:REACT_11210, GO:0005887=PMID:9059894, GO:0050776=Reactome:REACT_11152, GO:0004872=PMID:7749980, GO:0016021=PMID:7749980, GO:0003823=PMID:9059894} P43628 Killer cell immunoglobulin-like receptor 2DL3 protein 20130228 {GO:0005515=IPI, GO:0006955=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0050776=TAS, GO:0004872=TAS, GO:0016021=TAS, GO:0003823=TAS} immune response, regulation of immune response integral to membrane, integral to plasma membrane, plasma membrane antigen binding, protein binding, receptor activity Human KIR2DL4 Reactome UniProtKB {GO:0005515=PMID:18604210, GO:0007165=PMID:8946682, GO:0006968=PMID:8946682, GO:0005886=Reactome:REACT_11141, GO:0005887=PMID:8946682, GO:0050776=Reactome:REACT_11152, GO:0004888=PMID:8946682} Q99706 Killer cell immunoglobulin-like receptor 2DL4 protein 20070515 {GO:0005515=IPI, GO:0007165=TAS, GO:0006968=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0050776=TAS, GO:0004888=TAS} cellular defense response, regulation of immune response, signal transduction integral to plasma membrane, plasma membrane protein binding, transmembrane signaling receptor activity Human KIR2DS4 Reactome UniProtKB {GO:0005886=Reactome:REACT_147866, GO:0005887=PMID:7749980, GO:0045087=Reactome:REACT_6802} P43632 Killer cell immunoglobulin-like receptor 2DS4 protein 20120525 {GO:0005886=TAS, GO:0005887=TAS, GO:0045087=TAS} innate immune response integral to plasma membrane, plasma membrane Human KIR3DL1 UniProtKB UniProtKB {GO:0006955=PMID:8662091, GO:0005886=Reactome:REACT_11223, GO:0005887=PMID:8662091, GO:0050776=Reactome:REACT_11152, GO:0030109=PMID:7650366} Q14946 Killer cell immunoglobulin-like receptor 3DL1 protein 20010920 {GO:0006955=NAS, GO:0005886=TAS, GO:0005887=NAS, GO:0050776=TAS, GO:0030109=NAS} immune response, regulation of immune response integral to plasma membrane, plasma membrane HLA-B specific inhibitory MHC class I receptor activity Human KIR3DL2 Reactome UniProtKB {GO:0006968=PMID:7716543, GO:0005886=Reactome:REACT_11124, GO:0005887=PMID:7716543, GO:0050776=Reactome:REACT_11152} P43630 Killer cell immunoglobulin-like receptor 3DL2 protein 20070515 {GO:0006968=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0050776=TAS} cellular defense response, regulation of immune response integral to plasma membrane, plasma membrane Human KIRREL Reactome UniProtKB {GO:0005515=PMID:21402783, GO:0007588=GO_REF:0000019, GO:0016337=GO_REF:0000019, GO:0005886=Reactome:REACT_23929, GO:0030838=GO_REF:0000019, GO:0016020=GO_REF:0000038, GO:0005911=PMID:21402783, GO:0043198=GO_REF:0000019, GO:0001933=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q96J84 Kin of IRRE-like protein 1 protein 20120323 {GO:0005515=IPI, GO:0007588=IEA, GO:0016337=IEA, GO:0005886=TAS, GO:0030838=IEA, GO:0016020=IEA, GO:0005911=IDA, GO:0043198=IEA, GO:0001933=IEA, GO:0016021=IEA} cell-cell adhesion, excretion, negative regulation of protein phosphorylation, positive regulation of actin filament polymerization cell-cell junction, dendritic shaft, integral to membrane, membrane, plasma membrane protein binding Human KIRREL3 Reactome UniProtKB {GO:0005515=PMID:12424224, GO:0030097=GO_REF:0000024, GO:0030424=GO_REF:0000019, GO:0016020=GO_REF:0000038, GO:0005886=Reactome:REACT_23777, GO:0043198=GO_REF:0000019, GO:0021740=GO_REF:0000019, GO:0005576=GO_REF:0000024, GO:0016021=GO_REF:0000024, GO:0001764=GO_REF:0000019} Q8IZU9 Kin of IRRE-like protein 3 protein 20120323 {GO:0005515=IPI, GO:0030097=ISS, GO:0030424=IEA, GO:0016020=IEA, GO:0005886=TAS, GO:0043198=IEA, GO:0021740=IEA, GO:0005576=ISS, GO:0016021=ISS, GO:0001764=IEA} hemopoiesis, neuron migration, principal sensory nucleus of trigeminal nerve development axon, dendritic shaft, extracellular region, integral to membrane, membrane, plasma membrane protein binding Human KISS1 Reactome UniProtKB {GO:0005515=PMID:11387329, GO:0043005=GO_REF:0000019, GO:0060124=GO_REF:0000019, GO:0060112=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0033686=GO_REF:0000019, GO:0005576=Reactome:REACT_22436, GO:0005615=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0031773=GO_REF:0000019, GO:0050806=GO_REF:0000019, GO:0051482=GO_REF:0000019, GO:0007010=PMID:9192814, GO:0043025=GO_REF:0000019, GO:0043410=GO_REF:0000019} Q15726 Metastasis-suppressor KiSS-1 protein 20081218 {GO:0005515=IPI, GO:0043005=IEA, GO:0060124=IEA, GO:0060112=IEA, GO:0008285=IEA, GO:0033686=IEA, GO:0005576=TAS, GO:0005615=IEA, GO:0005737=IEA, GO:0016324=IEA, GO:0031773=IEA, GO:0050806=IEA, GO:0051482=IEA, GO:0007010=TAS, GO:0043025=IEA, GO:0043410=IEA} cytoskeleton organization, elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway, generation of ovulation cycle rhythm, negative regulation of cell proliferation, positive regulation of MAPK cascade, positive regulation of growth hormone secretion, positive regulation of luteinizing hormone secretion, positive regulation of synaptic transmission apical plasma membrane, cytoplasm, extracellular region, extracellular space, neuron projection, neuronal cell body kisspeptin receptor binding, protein binding Human KISS1R GOC UniProtKB {GO:0005515=PMID:11387329, GO:0008285=GO_REF:0000019, GO:0019722=GO_REF:0000019, GO:0005886=Reactome:REACT_22436, GO:0009986=GO_REF:0000019, GO:0004930=GO_REF:0000002, GO:0008188=PMID:11387329, GO:0000186=GO_REF:0000019, GO:0042923=GO_REF:0000019, GO:0007186=PMID:11387329, GO:0007218=PMID:11387329, GO:0050806=GO_REF:0000019, GO:0046887=GO_REF:0000019, GO:0051496=GO_REF:0000019, GO:0007610=PMID:11387329, GO:0016021=PMID:11387329, GO:0050482=GO_REF:0000019} Q969F8 KiSS-1 receptor protein 20130413 {GO:0005515=IPI, GO:0008285=IEA, GO:0019722=IEA, GO:0005886=TAS, GO:0009986=IEA, GO:0004930=IEA, GO:0008188=IDA, GO:0000186=IEA, GO:0042923=IEA, GO:0007186=NAS, GO:0007218=IDA, GO:0050806=IEA, GO:0046887=IEA, GO:0051496=IEA, GO:0007610=NAS, GO:0016021=IDA, GO:0050482=IEA} G-protein coupled receptor signaling pathway, activation of MAPKK activity, arachidonic acid secretion, behavior, calcium-mediated signaling, negative regulation of cell proliferation, neuropeptide signaling pathway, positive regulation of hormone secretion, positive regulation of stress fiber assembly, positive regulation of synaptic transmission cell surface, integral to membrane, plasma membrane G-protein coupled receptor activity, neuropeptide binding, neuropeptide receptor activity, protein binding Human KIT GOC UniProtKB {GO:0005515=PMID:17662946, GO:0008360=GO_REF:0000024, GO:0019221=PMID:21640708, GO:0007286=GO_REF:0000019, GO:0007283=GO_REF:0000024, GO:0002020=GO_REF:0000019, GO:0005615=PMID:14625290, GO:0007243=GO_REF:0000019, GO:0035234=GO_REF:0000019, GO:0042803=PMID:21640708, GO:0043069=GO_REF:0000019, GO:0046777=PMID:21640708, GO:0007173=Reactome:REACT_9417, GO:0043552=PMID:16129412, GO:0060374=GO_REF:0000024, GO:0042127=PMID:21057534, GO:0002327=GO_REF:0000024, GO:0023014=PMID:9438854, GO:0038162=GO_REF:0000024, GO:0002320=GO_REF:0000019, GO:0043303=PMID:20100931, GO:0031532=PMID:1721869, GO:0006687=GO_REF:0000019, GO:0032762=PMID:20100931, GO:0014068=PMID:16129412, GO:0018108=PMID:21640708, GO:0035855=GO_REF:0000024, GO:0019955=PMID:21640708, GO:0048070=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0002371=GO_REF:0000024, GO:0038093=PMID:20100931, GO:0002318=GO_REF:0000019, GO:0009897=GO_REF:0000019, GO:0097326=GO_REF:0000024, GO:0038109=PMID:17662946, GO:0097324=GO_REF:0000024, GO:0097067=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0005886=Reactome:REACT_147854, GO:0030032=GO_REF:0000024, GO:0042523=PMID:21135090, GO:0005634=GO_REF:0000052, GO:0046872=GO_REF:0000037, GO:0000187=PMID:21640708, GO:0005737=GO_REF:0000052, GO:0001541=GO_REF:0000024, GO:0051091=PMID:21135090, GO:0006954=GO_REF:0000024, GO:0005020=GO_REF:0000019, GO:0035162=GO_REF:0000024, GO:0009314=GO_REF:0000019, GO:0030097=PMID:16129412, GO:0048011=Reactome:REACT_11061, GO:0048015=Reactome:REACT_12464, GO:0042517=PMID:21135090, GO:0042511=PMID:21135090, GO:0048565=GO_REF:0000024, GO:0030318=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0046427=PMID:21135090, GO:0010863=PMID:16129412, GO:0048863=GO_REF:0000024, GO:0010628=GO_REF:0000019, GO:0007165=PMID:9990072, GO:0030217=GO_REF:0000024, GO:0070662=PMID:21057534, GO:0060326=PMID:1721869, GO:0050910=GO_REF:0000024, GO:0002551=PMID:20100931, GO:0019827=PMID:21057534, GO:0030218=GO_REF:0000024, GO:0043473=GO_REF:0000024, GO:0004713=PMID:1717985, GO:0016021=GO_REF:0000037, GO:0043410=PMID:21640708, GO:0004714=PMID:21640708, GO:0004716=GO_REF:0000002, GO:0008584=PMID:17848411} P10721 Mast/stem cell growth factor receptor Kit protein 20130413 {GO:0005515=IPI, GO:0008360=ISS, GO:0019221=IDA, GO:0007286=IEA, GO:0007283=ISS, GO:0002020=IEA, GO:0005615=IDA, GO:0007243=IEA, GO:0035234=IEA, GO:0042803=IPI, GO:0043069=IEA, GO:0046777=IDA, GO:0007173=TAS, GO:0043552=TAS, GO:0060374=ISS, GO:0042127=TAS, GO:0002327=ISS, GO:0023014=TAS, GO:0038162=ISS, GO:0002320=IEA, GO:0043303=IMP, GO:0031532=IDA, GO:0006687=IEA, GO:0032762=IDA, GO:0014068=TAS, GO:0018108=IDA, GO:0035855=ISS, GO:0019955=IDA, GO:0048070=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:0002371=ISS, GO:0038093=IDA, GO:0002318=IEA, GO:0009897=IEA, GO:0097326=ISS, GO:0038109=IDA, GO:0097324=ISS, GO:0097067=IEA, GO:0008284=IEA, GO:0005886=TAS, GO:0030032=ISS, GO:0042523=IMP, GO:0005634=IDA, GO:0046872=IEA, GO:0000187=IDA, GO:0005737=IDA, GO:0001541=ISS, GO:0051091=IMP, GO:0006954=ISS, GO:0005020=IEA, GO:0035162=ISS, GO:0009314=IEA, GO:0030097=TAS, GO:0048011=TAS, GO:0048015=TAS, GO:0042517=IMP, GO:0042511=IMP, GO:0048565=ISS, GO:0030318=ISS, GO:0005524=IEA, GO:0046427=IMP, GO:0010863=TAS, GO:0048863=ISS, GO:0010628=IEA, GO:0007165=TAS, GO:0030217=ISS, GO:0070662=TAS, GO:0060326=IDA, GO:0050910=ISS, GO:0002551=IDA, GO:0019827=TAS, GO:0030218=ISS, GO:0043473=ISS, GO:0004713=TAS, GO:0016021=IEA, GO:0043410=IMP, GO:0004714=IDA, GO:0004716=IEA, GO:0008584=IEP} Fc receptor signaling pathway, Kit signaling pathway, T cell differentiation, actin cytoskeleton reorganization, activation of MAPK activity, cell chemotaxis, cellular response to thyroid hormone stimulus, cytokine-mediated signaling pathway, dendritic cell cytokine production, detection of mechanical stimulus involved in sensory perception of sound, digestive tract development, embryonic hemopoiesis, epidermal growth factor receptor signaling pathway, erythrocyte differentiation, erythropoietin-mediated signaling pathway, fibroblast growth factor receptor signaling pathway, germ cell programmed cell death, glycosphingolipid metabolic process, hemopoiesis, immature B cell differentiation, inflammatory response, innate immune response, intracellular protein kinase cascade, lamellipodium assembly, lymphoid progenitor cell differentiation, male gonad development, mast cell chemotaxis, mast cell cytokine production, mast cell degranulation, mast cell differentiation, mast cell proliferation, megakaryocyte development, melanocyte adhesion, melanocyte differentiation, melanocyte migration, myeloid progenitor cell differentiation, negative regulation of programmed cell death, neurotrophin TRK receptor signaling pathway, ovarian follicle development, peptidyl-tyrosine phosphorylation, phosphatidylinositol-mediated signaling, pigmentation, positive regulation of JAK-STAT cascade, positive regulation of MAPK cascade, positive regulation of cell proliferation, positive regulation of gene expression, positive regulation of phosphatidylinositol 3-kinase activity, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of phospholipase C activity, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of tyrosine phosphorylation of Stat1 protein, positive regulation of tyrosine phosphorylation of Stat3 protein, positive regulation of tyrosine phosphorylation of Stat5 protein, protein autophosphorylation, regulation of cell proliferation, regulation of cell shape, regulation of developmental pigmentation, response to radiation, signal transduction, signal transduction by phosphorylation, spermatid development, spermatogenesis, stem cell differentiation, stem cell maintenance cytoplasm, external side of plasma membrane, extracellular space, integral to membrane, nucleus, plasma membrane ATP binding, cytokine binding, metal ion binding, protease binding, protein binding, protein homodimerization activity, protein tyrosine kinase activity, receptor signaling protein tyrosine kinase activity, stem cell factor receptor activity, transmembrane receptor protein tyrosine kinase activity Human KITLG BHF-UCL UniProtKB {GO:0005515=PMID:17662946, GO:0033026=GO_REF:0000019, GO:0005886=Reactome:REACT_111098, GO:0008283=PMID:2208279, GO:0001755=GO_REF:0000019, GO:0050731=GO_REF:0000019, GO:0046579=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0035234=GO_REF:0000019, GO:0005737=GO_REF:0000037, GO:0007173=Reactome:REACT_9417, GO:0043406=GO_REF:0000019, GO:0045636=GO_REF:0000019, GO:0007155=GO_REF:0000037, GO:0005856=GO_REF:0000039, GO:0035162=PMID:21149635, GO:0030097=GO_REF:0000029, GO:0048011=Reactome:REACT_11061, GO:0048015=Reactome:REACT_12464, GO:0045740=PMID:9722506, GO:0005576=Reactome:REACT_147854, GO:0005125=GO_REF:0000019, GO:0007165=PMID:2208279, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0002763=GO_REF:0000019, GO:0016021=GO_REF:0000019, GO:0008083=GO_REF:0000037, GO:0005173=GO_REF:0000029, GO:0008584=PMID:17848411, GO:0070668=GO_REF:0000019} P21583 Kit ligand protein 20080530 {GO:0005515=IPI, GO:0033026=IEA, GO:0005886=TAS, GO:0008283=TAS, GO:0001755=IEA, GO:0050731=IEA, GO:0046579=IEA, GO:0005615=IEA, GO:0035234=IEA, GO:0005737=IEA, GO:0007173=TAS, GO:0043406=IEA, GO:0045636=IEA, GO:0007155=IEA, GO:0005856=IEA, GO:0035162=IDA, GO:0030097=NAS, GO:0048011=TAS, GO:0048015=TAS, GO:0045740=IDA, GO:0005576=TAS, GO:0005125=IEA, GO:0007165=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0002763=IEA, GO:0016021=IEA, GO:0008083=IEA, GO:0005173=NAS, GO:0008584=IEP, GO:0070668=IEA} cell adhesion, cell proliferation, embryonic hemopoiesis, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, germ cell programmed cell death, hemopoiesis, innate immune response, male gonad development, negative regulation of mast cell apoptotic process, neural crest cell migration, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of DNA replication, positive regulation of MAP kinase activity, positive regulation of Ras protein signal transduction, positive regulation of mast cell proliferation, positive regulation of melanocyte differentiation, positive regulation of myeloid leukocyte differentiation, positive regulation of peptidyl-tyrosine phosphorylation, signal transduction cytoplasm, cytoskeleton, extracellular region, extracellular space, integral to membrane, plasma membrane cytokine activity, growth factor activity, protein binding, stem cell factor receptor binding Human KL Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0048011=Reactome:REACT_11061, GO:0002526=GO_REF:0000019, GO:0004566=GO_REF:0000003, GO:0030501=PMID:12110410, GO:0005886=Reactome:REACT_111055, GO:0005975=GO_REF:0000002, GO:0017134=PMID:18829467, GO:0048015=Reactome:REACT_12464, GO:0007568=PMID:11792841, GO:0005576=Reactome:REACT_147854, GO:0005104=GO_REF:0000019, GO:0004553=GO_REF:0000002, GO:0055074=GO_REF:0000019, GO:0006112=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0005179=GO_REF:0000037, GO:0008543=Reactome:REACT_9484, GO:0005887=PMID:9464267, GO:0045087=Reactome:REACT_6802, GO:0005499=GO_REF:0000037, GO:0004871=PMID:9363890, GO:0008422=PMID:9363890, GO:0090080=GO_REF:0000019} Q9UEF7 Klotho protein 20070202 {GO:0008286=TAS, GO:0048011=TAS, GO:0002526=IEA, GO:0004566=IEA, GO:0030501=IMP, GO:0005886=TAS, GO:0005975=IEA, GO:0017134=IPI, GO:0048015=TAS, GO:0007568=IMP, GO:0005576=TAS, GO:0005104=IEA, GO:0004553=IEA, GO:0055074=IEA, GO:0006112=IEA, GO:0007173=TAS, GO:0005179=IEA, GO:0008543=TAS, GO:0005887=TAS, GO:0045087=TAS, GO:0005499=IEA, GO:0004871=TAS, GO:0008422=TAS, GO:0090080=IEA} acute inflammatory response, aging, calcium ion homeostasis, carbohydrate metabolic process, energy reserve metabolic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway, positive regulation of bone mineralization extracellular region, integral to plasma membrane, plasma membrane beta-glucosidase activity, beta-glucuronidase activity, fibroblast growth factor binding, fibroblast growth factor receptor binding, hormone activity, hydrolase activity, hydrolyzing O-glycosyl compounds, signal transducer activity, vitamin D binding Human KLB Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0008284=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0005886=Reactome:REACT_147854, GO:0005975=GO_REF:0000002, GO:0017134=PMID:19117008, GO:0048015=Reactome:REACT_12464, GO:0004553=GO_REF:0000002, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0016021=GO_REF:0000037, GO:0090080=GO_REF:0000019} Q86Z14 Beta-klotho protein 20130301 {GO:0008286=TAS, GO:0008284=IEA, GO:0048011=TAS, GO:0005886=TAS, GO:0005975=IEA, GO:0017134=IPI, GO:0048015=TAS, GO:0004553=IEA, GO:0007173=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0016021=IEA, GO:0090080=IEA} carbohydrate metabolic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway, positive regulation of cell proliferation integral to membrane, plasma membrane fibroblast growth factor binding, hydrolase activity, hydrolyzing O-glycosyl compounds Human KLC1 BHF-UCL UniProtKB {GO:0005515=PMID:19861499, GO:0019886=Reactome:REACT_121399, GO:0003774=PMID:8786116, GO:0005871=GO_REF:0000024, GO:0007596=Reactome:REACT_604, GO:0019048=GO_REF:0000037, GO:0005874=GO_REF:0000037, GO:0003777=GO_REF:0000002, GO:0035617=GO_REF:0000024, GO:0007018=Reactome:REACT_25201, GO:0005829=Reactome:REACT_120995} Q07866 Kinesin light chain 1 protein 20110110 {GO:0005515=IPI, GO:0019886=TAS, GO:0003774=TAS, GO:0005871=ISS, GO:0007596=TAS, GO:0019048=IEA, GO:0005874=IEA, GO:0003777=IEA, GO:0035617=ISS, GO:0007018=TAS, GO:0005829=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, blood coagulation, microtubule-based movement, stress granule disassembly, virus-host interaction cytosol, kinesin complex, microtubule microtubule motor activity, motor activity, protein binding Human UniProtKB:O88447 KLC2 BHF-UCL UniProtKB {GO:0005515=PMID:14985359, GO:0043005=GO_REF:0000019, GO:0005871=GO_REF:0000024, GO:0005874=GO_REF:0000037, GO:0016938=PMID:20510358, GO:0003777=GO_REF:0000002, GO:0005829=Reactome:REACT_120995, GO:0019886=Reactome:REACT_121399, GO:0043234=GO_REF:0000054, GO:0005737=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0035253=GO_REF:0000019, GO:0008088=GO_REF:0000019, GO:0019894=GO_REF:0000024, GO:0007018=Reactome:REACT_25201} Q9H0B6 Kinesin light chain 2 protein 20111118 {GO:0005515=IPI, GO:0043005=IEA, GO:0005871=ISS, GO:0005874=IEA, GO:0016938=NAS, GO:0003777=IEA, GO:0005829=TAS, GO:0019886=TAS, GO:0043234=IDA, GO:0005737=IEA, GO:0007596=TAS, GO:0035253=IEA, GO:0008088=IEA, GO:0019894=ISS, GO:0007018=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, axon cargo transport, blood coagulation, microtubule-based movement ciliary rootlet, cytoplasm, cytosol, kinesin I complex, kinesin complex, microtubule, neuron projection, protein complex kinesin binding, microtubule motor activity, protein binding Human KLC3 ENSEMBL UniProtKB {GO:0008017=GO_REF:0000019, GO:0043005=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0005871=GO_REF:0000002, GO:0008808=GO_REF:0000019, GO:0035253=GO_REF:0000019, GO:0005874=GO_REF:0000037, GO:0019894=GO_REF:0000019, GO:0003777=GO_REF:0000002} Q6P597 Kinesin light chain 3 protein 20130413 {GO:0008017=IEA, GO:0043005=IEA, GO:0005737=IEA, GO:0005871=IEA, GO:0008808=IEA, GO:0035253=IEA, GO:0005874=IEA, GO:0019894=IEA, GO:0003777=IEA} ciliary rootlet, cytoplasm, kinesin complex, microtubule, neuron projection cardiolipin synthase activity, kinesin binding, microtubule binding, microtubule motor activity Human Ensembl:ENSMUSP00000038091 KLC4 UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0005871=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0003777=GO_REF:0000002} Q9NSK0 Kinesin light chain 4 protein 20130413 {GO:0005737=IEA, GO:0005871=IEA, GO:0005874=IEA, GO:0003777=IEA} cytoplasm, kinesin complex, microtubule microtubule motor activity Human UniProtKB-KW:KW-0493 KLF1 BHF-UCL UniProtKB {GO:0000987=PMID:21539536, GO:0000790=PMID:21539536, GO:0003700=PMID:9778250, GO:0044212=PMID:20676099, GO:0005634=PMID:21055716, GO:0001701=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0001889=GO_REF:0000019, GO:0043249=GO_REF:0000019, GO:0030218=PMID:21055716, GO:0008270=GO_REF:0000002, GO:0006338=GO_REF:0000019, GO:0045893=PMID:20676099, GO:0035162=GO_REF:0000019} Q13351 Krueppel-like factor 1 protein 20111118 {GO:0000987=IDA, GO:0000790=IDA, GO:0003700=TAS, GO:0044212=IDA, GO:0005634=IDA, GO:0001701=IEA, GO:0006351=IEA, GO:0001889=IEA, GO:0043249=IEA, GO:0030218=IMP, GO:0008270=IEA, GO:0006338=IEA, GO:0045893=IDA, GO:0035162=IEA} chromatin remodeling, embryonic hemopoiesis, erythrocyte differentiation, erythrocyte maturation, in utero embryonic development, liver development, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent nuclear chromatin, nucleus core promoter proximal region sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding, zinc ion binding Human KLF10 IntAct UniProtKB {GO:0005515=PMID:10976766, GO:0008285=PMID:9748269, GO:0003700=PMID:9748269, GO:0008283=PMID:10816551, GO:0007267=PMID:8532536, GO:0045672=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0006917=GO_REF:0000019, GO:0030282=GO_REF:0000019, GO:0000122=PMID:9748269, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0001501=PMID:10816551, GO:0008270=GO_REF:0000002, GO:0007179=PMID:10816551, GO:0035019=GO_REF:0000019} Q13118 Krueppel-like factor 10 protein 20130415 {GO:0005515=IPI, GO:0008285=TAS, GO:0003700=TAS, GO:0008283=TAS, GO:0007267=TAS, GO:0045672=IEA, GO:0005634=IEA, GO:0006917=IEA, GO:0030282=IEA, GO:0000122=TAS, GO:0003677=IEA, GO:0006351=IEA, GO:0001501=TAS, GO:0008270=IEA, GO:0007179=TAS, GO:0035019=IEA} bone mineralization, cell proliferation, cell-cell signaling, induction of apoptosis, negative regulation of cell proliferation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of osteoclast differentiation, skeletal system development, somatic stem cell maintenance, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway nucleus DNA binding, protein binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB:P08047 KLF11 BHF-UCL UniProtKB {GO:0008285=PMID:21171965, GO:0043065=PMID:21171965, GO:0003700=PMID:9748269, GO:0044212=PMID:21171965, GO:0006366=PMID:9748269, GO:0000115=PMID:21171965, GO:0000981=PMID:21171965, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0000122=PMID:21171965, GO:0045892=GO_REF:0000019} O14901 Krueppel-like factor 11 protein 20110324 {GO:0008285=IDA, GO:0043065=IDA, GO:0003700=TAS, GO:0044212=IDA, GO:0006366=TAS, GO:0000115=IDA, GO:0000981=IDA, GO:0006915=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0000122=IDA, GO:0045892=IEA} apoptotic process, negative regulation of cell proliferation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of apoptotic process, regulation of transcription involved in S phase of mitotic cell cycle, transcription from RNA polymerase II promoter nucleus sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding, zinc ion binding Human KLF12 PINC UniProtKB {GO:0003700=PMID:16615998, GO:0006357=PMID:10704285, GO:0003714=PMID:10704285, GO:0045944=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0000122=PMID:16615998, GO:0003677=PMID:16615998, GO:0006351=GO_REF:0000037} Q9Y4X4 Krueppel-like factor 12 protein 20030904 {GO:0003700=IDA, GO:0006357=TAS, GO:0003714=TAS, GO:0045944=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0000122=IDA, GO:0003677=IDA, GO:0006351=IEA} negative regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity, zinc ion binding Human KLF13 PINC UniProtKB {GO:0008285=GO_REF:0000019, GO:0006366=PMID:10023774, GO:0045647=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000019} Q9Y2Y9 Krueppel-like factor 13 protein 20030904 {GO:0008285=IEA, GO:0006366=TAS, GO:0045647=IEA, GO:0045944=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA} negative regulation of cell proliferation, negative regulation of erythrocyte differentiation, positive regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter nucleus DNA binding, nucleic acid binding, zinc ion binding Human KLF14 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8TD94 Krueppel-like factor 14 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 KLF15 HPA UniProtKB {GO:0001077=PMID:19767294, GO:0015758=GO_REF:0000019, GO:0045944=PMID:19767294, GO:0005730=GO_REF:0000052, GO:0010001=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000019} Q9UIH9 Krueppel-like factor 15 protein 20110516 {GO:0001077=IC, GO:0015758=IEA, GO:0045944=IMP, GO:0005730=IDA, GO:0010001=IEA, GO:0008270=IEA, GO:0003677=IEA} glial cell differentiation, glucose transport, positive regulation of transcription from RNA polymerase II promoter nucleolus DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, zinc ion binding Human KLF16 UniProtKB UniProtKB {GO:0003700=GO_REF:0000019, GO:0006357=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0007212=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q9BXK1 Krueppel-like factor 16 protein 20130413 {GO:0003700=IEA, GO:0006357=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0007212=IEA, GO:0003677=IEA, GO:0006351=IEA} dopamine receptor signaling pathway, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB-SubCell:SL-0191 KLF2 BHF-UCL UniProtKB {GO:0071499=PMID:23043106, GO:0070301=GO_REF:0000019, GO:0003700=GO_REF:0000029, GO:0032715=GO_REF:0000019, GO:0005634=GO_REF:0000029, GO:0001701=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000019, GO:0000902=GO_REF:0000019, GO:0043249=GO_REF:0000019, GO:0035264=GO_REF:0000019, GO:0071347=GO_REF:0000019, GO:0071356=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0045893=GO_REF:0000029, GO:0036003=PMID:23043106} Q9Y5W3 Krueppel-like factor 2 protein 20121203 {GO:0071499=IMP, GO:0070301=IEA, GO:0003700=NAS, GO:0032715=IEA, GO:0005634=NAS, GO:0001701=IEA, GO:0006351=IEA, GO:0043565=IEA, GO:0000902=IEA, GO:0043249=IEA, GO:0035264=IEA, GO:0071347=IEA, GO:0071356=IEA, GO:0008270=IEA, GO:0045893=NAS, GO:0036003=IMP} cell morphogenesis, cellular response to hydrogen peroxide, cellular response to interleukin-1, cellular response to laminar fluid shear stress, cellular response to tumor necrosis factor, erythrocyte maturation, in utero embryonic development, multicellular organism growth, negative regulation of interleukin-6 production, positive regulation of transcription from RNA polymerase II promoter in response to stress, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human KLF3 PINC UniProtKB {GO:0003700=PMID:10582345, GO:0007275=PMID:10582345, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P57682 Krueppel-like factor 3 protein 20030904 {GO:0003700=NAS, GO:0007275=TAS, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} multicellular organismal development, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human KLF4 HPA UniProtKB {GO:0000987=PMID:21539536, GO:0051898=GO_REF:0000019, GO:0000790=PMID:21539536, GO:0001190=PMID:21539536, GO:0008285=PMID:8702718, GO:0003700=PMID:9422764, GO:0006366=GO_REF:0000024, GO:0044212=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0048730=GO_REF:0000019, GO:0003690=GO_REF:0000019, GO:0045944=GO_REF:0000024, GO:0001085=GO_REF:0000019, GO:0034115=PMID:20551324, GO:0045444=GO_REF:0000019, GO:0070373=GO_REF:0000019, GO:0032526=GO_REF:0000019, GO:0043154=PMID:20551324, GO:0000785=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0045415=PMID:20551324, GO:0035014=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0032088=PMID:20551324, GO:0048662=GO_REF:0000019, GO:0014067=GO_REF:0000019, GO:2000342=PMID:20551324, GO:0031077=GO_REF:0000019, GO:0009913=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0001077=GO_REF:0000019, GO:0007500=PMID:8940147, GO:0014740=GO_REF:0000019, GO:0050728=PMID:20551324, GO:0019827=GO_REF:0000019, GO:0008270=PMID:9422764, GO:0045595=GO_REF:0000024, GO:0045893=GO_REF:0000024, GO:0045892=PMID:9422764, GO:0001010=GO_REF:0000019} Q5T3J6 Krueppel-like factor 4 protein 20100326 {GO:0000987=IDA, GO:0051898=IEA, GO:0000790=IDA, GO:0001190=IDA, GO:0008285=TAS, GO:0003700=NAS, GO:0006366=ISS, GO:0044212=IEA, GO:0005634=IDA, GO:0048730=IEA, GO:0003690=IEA, GO:0045944=ISS, GO:0001085=IEA, GO:0034115=IDA, GO:0045444=IEA, GO:0070373=IEA, GO:0032526=IEA, GO:0043154=IDA, GO:0000785=IEA, GO:0005667=IEA, GO:0045415=IDA, GO:0035014=IEA, GO:0005730=IDA, GO:0032088=IDA, GO:0048662=IEA, GO:0014067=IEA, GO:2000342=IDA, GO:0031077=IEA, GO:0009913=IEA, GO:0043565=IEA, GO:0001077=IEA, GO:0007500=TAS, GO:0014740=IEA, GO:0050728=TAS, GO:0019827=IEA, GO:0008270=NAS, GO:0045595=ISS, GO:0045893=ISS, GO:0045892=IDA, GO:0001010=IEA} epidermal cell differentiation, epidermis morphogenesis, fat cell differentiation, mesodermal cell fate determination, negative regulation of ERK1 and ERK2 cascade, negative regulation of NF-kappaB transcription factor activity, negative regulation of cell proliferation, negative regulation of chemokine (C-X-C motif) ligand 2 production, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of heterotypic cell-cell adhesion, negative regulation of inflammatory response, negative regulation of interleukin-8 biosynthetic process, negative regulation of muscle hyperplasia, negative regulation of phosphatidylinositol 3-kinase cascade, negative regulation of protein kinase B signaling cascade, negative regulation of smooth muscle cell proliferation, negative regulation of transcription, DNA-dependent, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, post-embryonic camera-type eye development, regulation of cell differentiation, response to retinoic acid, stem cell maintenance, transcription from RNA polymerase II promoter chromatin, nuclear chromatin, nucleolus, nucleus, transcription factor complex RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II transcription factor binding, RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription, core promoter proximal region sequence-specific DNA binding, double-stranded DNA binding, phosphatidylinositol 3-kinase regulator activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, sequence-specific DNA binding transcription factor recruiting transcription factor activity, transcription regulatory region DNA binding, zinc ion binding NOT Human KLF5 HPA UniProtKB {GO:0005794=GO_REF:0000052, GO:0003700=GO_REF:0000019, GO:0006366=PMID:8479902, GO:0030033=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0001525=GO_REF:0000019, GO:0045893=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0043231=GO_REF:0000052} Q13887 Krueppel-like factor 5 protein 20110516 {GO:0005794=IDA, GO:0003700=IEA, GO:0006366=TAS, GO:0030033=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0001525=IEA, GO:0045893=IEA, GO:0003677=IEA, GO:0043231=IDA} angiogenesis, microvillus assembly, positive regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter Golgi apparatus, intracellular membrane-bounded organelle, nucleolus, nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human KLF6 UniProtKB UniProtKB {GO:0006355=GO_REF:0000029, GO:0005737=GO_REF:0000019, GO:0030183=PMID:9000136, GO:0019221=GO_REF:0000019, GO:0005634=PMID:9689109, GO:0008270=GO_REF:0000002, GO:0045893=PMID:9083102, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q99612 Krueppel-like factor 6 protein 20021104 {GO:0006355=NAS, GO:0005737=IEA, GO:0030183=NAS, GO:0019221=IEA, GO:0005634=TAS, GO:0008270=IEA, GO:0045893=TAS, GO:0003677=IEA, GO:0006351=IEA} B cell differentiation, cytokine-mediated signaling pathway, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus DNA binding, zinc ion binding Human KLF7 PINC UniProtKB {GO:0048813=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0006357=PMID:9774444, GO:0007411=GO_REF:0000019, GO:0003713=PMID:9774444, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0045893=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O75840 Krueppel-like factor 7 protein 20030904 {GO:0048813=IEA, GO:0003700=IEA, GO:0006357=TAS, GO:0007411=IEA, GO:0003713=TAS, GO:0005634=IEA, GO:0008270=IEA, GO:0045893=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} axon guidance, dendrite morphogenesis, positive regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, zinc ion binding Human KLF8 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O95600 Krueppel-like factor 8 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 KLF9 PINC UniProtKB {GO:0050847=GO_REF:0000019, GO:0097067=PMID:19375645, GO:0003700=PMID:8051167, GO:0006357=PMID:1356762, GO:0007566=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q13886 Krueppel-like factor 9 protein 20030904 {GO:0050847=IEA, GO:0097067=IDA, GO:0003700=TAS, GO:0006357=TAS, GO:0007566=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} cellular response to thyroid hormone stimulus, embryo implantation, progesterone receptor signaling pathway, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human KLHDC10 null null {} null null null null {} null null null KLHDC2 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039} Q9Y2U9 Kelch domain-containing protein 2 protein 20130413 {GO:0005634=IEA} nucleus Human UniProtKB-SubCell:SL-0191 KLHDC3 Reactome UniProtKB {GO:0005515=PMID:12482870, GO:0005737=PMID:12606021, GO:0000790=PMID:12606021, GO:0003682=PMID:12606021, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0030968=Reactome:REACT_18356, GO:0005829=Reactome:REACT_115919, GO:0007131=PMID:12606021} Q9BQ90 Kelch domain-containing protein 3 protein 20130301 {GO:0005515=IPI, GO:0005737=IDA, GO:0000790=IDA, GO:0003682=IDA, GO:0006987=TAS, GO:0044267=TAS, GO:0030968=TAS, GO:0005829=TAS, GO:0007131=NAS} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, reciprocal meiotic recombination cytoplasm, cytosol, nuclear chromatin chromatin binding, protein binding Human KLHDC4 null null {} null null null null {} null null null KLHDC8A null null {} null null null null {} null null null KLHDC8B HPA UniProtKB {GO:0005737=GO_REF:0000052} Q8IXV7 Kelch domain-containing protein 8B protein 20090616 {GO:0005737=IDA} cytoplasm Human KLHDC9 null null {} null null null null {} null null null KLHL1 UniProtKB UniProtKB {GO:0005737=PMID:10888605, GO:0030036=PMID:10888605, GO:0021680=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0007628=GO_REF:0000019, GO:0003779=PMID:10888605, GO:0005856=GO_REF:0000039, GO:0030425=GO_REF:0000019, GO:0016358=GO_REF:0000019} Q9NR64 Kelch-like protein 1 protein 20010918 {GO:0005737=IDA, GO:0030036=NAS, GO:0021680=IEA, GO:0043025=IEA, GO:0007628=IEA, GO:0003779=NAS, GO:0005856=IEA, GO:0030425=IEA, GO:0016358=IEA} actin cytoskeleton organization, adult walking behavior, cerebellar Purkinje cell layer development, dendrite development cytoplasm, cytoskeleton, dendrite, neuronal cell body actin binding Human KLHL10 UniProtKB UniProtKB {GO:0009566=GO_REF:0000019, GO:0000902=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0048873=GO_REF:0000019, GO:0007286=GO_REF:0000019, GO:0048808=GO_REF:0000019, GO:0008584=GO_REF:0000019} Q6JEL2 Kelch-like protein 10 protein 20130413 {GO:0009566=IEA, GO:0000902=IEA, GO:0005737=IEA, GO:0048873=IEA, GO:0007286=IEA, GO:0048808=IEA, GO:0008584=IEA} cell morphogenesis, fertilization, homeostasis of number of cells within a tissue, male genitalia morphogenesis, male gonad development, spermatid development cytoplasm Human UniProtKB-SubCell:SL-0086 KLHL11 null null {} null null null null {} null null null KLHL12 IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0006888=PMID:22358839, GO:0030134=PMID:22358839, GO:0006513=PMID:22358839, GO:0031463=PMID:22358839, GO:0048208=PMID:22358839, GO:0016055=PMID:20970343} Q53G59 Kelch-like protein 12 protein 20130415 {GO:0005515=IPI, GO:0006888=IDA, GO:0030134=IDA, GO:0006513=IDA, GO:0031463=IDA, GO:0048208=IMP, GO:0016055=IMP} COPII vesicle coating, ER to Golgi vesicle-mediated transport, Wnt receptor signaling pathway, protein monoubiquitination Cul3-RING ubiquitin ligase complex, ER to Golgi transport vesicle protein binding Human UniProtKB:P54253 KLHL13 UniProtKB UniProtKB {GO:0000910=PMID:17543862, GO:0004842=PMID:17543862, GO:0007067=GO_REF:0000037, GO:0016567=PMID:17543862, GO:0031463=PMID:17543862} Q9P2N7 Kelch-like protein 13 protein 20100608 {GO:0000910=IMP, GO:0004842=IDA, GO:0007067=IEA, GO:0016567=IDA, GO:0031463=IDA} cytokinesis, mitosis, protein ubiquitination Cul3-RING ubiquitin ligase complex ubiquitin-protein ligase activity contributes_to Human KLHL14 MGI UniProtKB {GO:0043005=GO_REF:0000019, GO:0005783=PMID:19535332, GO:0005789=GO_REF:0000039, GO:0043025=GO_REF:0000019, GO:0005829=GO_REF:0000039} Q9P2G3 Kelch-like protein 14 protein 20120504 {GO:0043005=IEA, GO:0005783=IDA, GO:0005789=IEA, GO:0043025=IEA, GO:0005829=IEA} cytosol, endoplasmic reticulum, endoplasmic reticulum membrane, neuron projection, neuronal cell body Human KLHL15 UniPathway UniProtKB {GO:0016567=GO_REF:0000041} Q96M94 Kelch-like protein 15 protein 20130413 {GO:0016567=IEA} protein ubiquitination Human UniPathway:UPA00143 KLHL17 UniProtKB UniProtKB {GO:0031208=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0016567=GO_REF:0000041, GO:0030036=GO_REF:0000024, GO:0005886=GO_REF:0000037, GO:0014069=GO_REF:0000039, GO:0032839=GO_REF:0000019, GO:0015629=GO_REF:0000024, GO:0032947=GO_REF:0000024, GO:0051015=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0045211=GO_REF:0000037, GO:0043025=GO_REF:0000019} Q6TDP4 Kelch-like protein 17 protein 20110427 {GO:0031208=IEA, GO:0030054=IEA, GO:0016567=IEA, GO:0030036=ISS, GO:0005886=IEA, GO:0014069=IEA, GO:0032839=IEA, GO:0015629=ISS, GO:0032947=ISS, GO:0051015=IEA, GO:0007420=IEA, GO:0045211=IEA, GO:0043025=IEA} actin cytoskeleton organization, brain development, protein ubiquitination actin cytoskeleton, cell junction, dendrite cytoplasm, neuronal cell body, plasma membrane, postsynaptic density, postsynaptic membrane POZ domain binding, actin filament binding, protein complex scaffold Human UniProtKB:Q8K430 KLHL18 null null {} null null null null {} null null null KLHL2 UniProtKB UniProtKB {GO:0005515=PMID:21784977, GO:0005737=GO_REF:0000024, GO:0016567=GO_REF:0000024, GO:0031463=GO_REF:0000024, GO:0003779=PMID:10397770, GO:0015629=PMID:10397770, GO:0001726=GO_REF:0000039, GO:0030027=GO_REF:0000039, GO:0005829=GO_REF:0000039} O95198 Kelch-like protein 2 protein 20111209 {GO:0005515=IPI, GO:0005737=ISS, GO:0016567=ISS, GO:0031463=ISS, GO:0003779=IDA, GO:0015629=IDA, GO:0001726=IEA, GO:0030027=IEA, GO:0005829=IEA} protein ubiquitination Cul3-RING ubiquitin ligase complex, actin cytoskeleton, cytoplasm, cytosol, lamellipodium, ruffle actin binding, protein binding Human UniProtKB:P26651 KLHL20 HPA UniProtKB {GO:0005515=PMID:20389280, GO:0048471=GO_REF:0000039, GO:0043066=PMID:20389280, GO:0004842=PMID:20389280, GO:0005794=GO_REF:0000052, GO:0016567=PMID:20389280, GO:0009986=PMID:12493773, GO:0035455=PMID:20389280, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003779=GO_REF:0000037, GO:0015629=PMID:10888605, GO:0044444=PMID:20389280, GO:0005737=GO_REF:0000052, GO:0019964=PMID:20389280, GO:0016605=PMID:20389280, GO:0007010=PMID:10888605, GO:0031463=PMID:20389280, GO:0043161=PMID:20389280} Q9Y2M5 Kelch-like protein 20 protein 20101115 {GO:0005515=IPI, GO:0048471=IEA, GO:0043066=IMP, GO:0004842=IDA, GO:0005794=IDA, GO:0016567=IDA, GO:0009986=IDA, GO:0035455=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0003779=IEA, GO:0015629=TAS, GO:0044444=IDA, GO:0005737=IDA, GO:0019964=IDA, GO:0016605=IDA, GO:0007010=TAS, GO:0031463=IDA, GO:0043161=IDA} cytoskeleton organization, negative regulation of apoptotic process, proteasomal ubiquitin-dependent protein catabolic process, protein ubiquitination, response to interferon-alpha Cul3-RING ubiquitin ligase complex, Golgi apparatus, PML body, actin cytoskeleton, cell surface, cytoplasm, cytoplasmic part, nucleolus, nucleus, perinuclear region of cytoplasm actin binding, interferon-gamma binding, protein binding, ubiquitin-protein ligase activity Human KLHL21 UniProtKB UniProtKB {GO:0005827=PMID:19995937, GO:0000910=PMID:19995937, GO:0004842=PMID:19995937, GO:0007067=GO_REF:0000037, GO:0005737=GO_REF:0000037, GO:0016567=PMID:19995937, GO:0051322=PMID:19995937, GO:0031463=PMID:19995937} Q9UJP4 Kelch-like protein 21 protein 20100608 {GO:0005827=IDA, GO:0000910=IMP, GO:0004842=IDA, GO:0007067=IEA, GO:0005737=IEA, GO:0016567=IDA, GO:0051322=IMP, GO:0031463=IDA} anaphase, cytokinesis, mitosis, protein ubiquitination Cul3-RING ubiquitin ligase complex, cytoplasm, polar microtubule ubiquitin-protein ligase activity contributes_to Human KLHL22 UniProtKB UniProtKB {GO:0016567=GO_REF:0000041, GO:0031463=PMID:19995937, GO:0051301=PMID:19995937} Q53GT1 Kelch-like protein 22 protein 20100608 {GO:0016567=IEA, GO:0031463=IDA, GO:0051301=IMP} cell division, protein ubiquitination Cul3-RING ubiquitin ligase complex Human KLHL23 null null {} null null null null {} null null null KLHL24 UniProtKB UniProtKB {GO:0030424=GO_REF:0000039, GO:0005737=GO_REF:0000039, GO:0043204=GO_REF:0000039} Q6TFL4 Kelch-like protein 24 protein 20130413 {GO:0030424=IEA, GO:0005737=IEA, GO:0043204=IEA} axon, cytoplasm, perikaryon Human UniProtKB-SubCell:SL-0197 KLHL25 LIFEdb UniProtKB {GO:0005737=GO_REF:0000054} Q9H0H3 Ectoderm-neural cortex protein 2 protein 20100607 {GO:0005737=IDA} cytoplasm Human KLHL26 null null {} null null null null {} null null null KLHL28 null null {} null null null null {} null null null KLHL29 null null {} null null null null {} null null null KLHL3 PINC UniProtKB {GO:0005515=PMID:22406640, GO:0016567=PMID:22406640, GO:0005198=PMID:10843806, GO:0031463=PMID:22406640, GO:0072156=PMID:22406640, GO:0003779=GO_REF:0000037, GO:0005856=GO_REF:0000039, GO:0070294=PMID:22406640, GO:0005829=PMID:22406640} Q9UH77 Kelch-like protein 3 protein 20030904 {GO:0005515=IPI, GO:0016567=TAS, GO:0005198=TAS, GO:0031463=TAS, GO:0072156=IMP, GO:0003779=IEA, GO:0005856=IEA, GO:0070294=IMP, GO:0005829=IDA} distal tubule morphogenesis, protein ubiquitination, renal sodium ion absorption Cul3-RING ubiquitin ligase complex, cytoskeleton, cytosol actin binding, protein binding, structural molecule activity Human KLHL31 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9H511 Kelch-like protein 31 protein 20130413 {GO:0006355=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent Human UniProtKB-KW:KW-0805 KLHL32 null null {} null null null null {} null null null KLHL34 null null {} null null null null {} null null null KLHL35 null null {} null null null null {} null null null KLHL36 UniPathway UniProtKB {GO:0016567=GO_REF:0000041} Q8N4N3 Kelch-like protein 36 protein 20130413 {GO:0016567=IEA} protein ubiquitination Human UniPathway:UPA00143 KLHL38 IntAct UniProtKB {GO:0005515=PMID:22939624} Q2WGJ6 Kelch-like protein 38 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:P08238 KLHL4 HPA UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0015630=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003779=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q9C0H6 Kelch-like protein 4 protein 20101115 {GO:0003674=ND, GO:0008150=ND, GO:0005737=IDA, GO:0015630=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0003779=IEA, GO:0043231=IDA} biological_process cytoplasm, intracellular membrane-bounded organelle, microtubule cytoskeleton, nucleolus, nucleus actin binding, molecular_function Human KLHL5 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005737=PMID:14672410, GO:0003779=GO_REF:0000037, GO:0005856=GO_REF:0000039} Q96PQ7 Kelch-like protein 5 protein 20090724 {GO:0003674=ND, GO:0008150=ND, GO:0005737=NAS, GO:0003779=IEA, GO:0005856=IEA} biological_process cytoplasm, cytoskeleton actin binding, molecular_function Human KLHL6 ENSEMBL UniProtKB {GO:0050853=GO_REF:0000019, GO:0002467=GO_REF:0000019} Q8WZ60 Kelch-like protein 6 protein 20130413 {GO:0050853=IEA, GO:0002467=IEA} B cell receptor signaling pathway, germinal center formation Human Ensembl:ENSMUSP00000053023 KLHL7 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0016567=PMID:21828050, GO:0005886=GO_REF:0000052, GO:0031463=PMID:21828050, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0042803=PMID:21828050} Q8IXQ5 Kelch-like protein 7 protein 20111111 {GO:0005737=IDA, GO:0016567=IDA, GO:0005886=IDA, GO:0031463=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0042803=IDA} protein ubiquitination Cul3-RING ubiquitin ligase complex, cytoplasm, nucleolus, nucleus, plasma membrane protein homodimerization activity Human KLHL8 null null {} null null null null {} null null null KLHL9 UniProtKB UniProtKB {GO:0000910=PMID:17543862, GO:0004842=PMID:17543862, GO:0007067=GO_REF:0000037, GO:0016567=PMID:17543862, GO:0031463=PMID:17543862, GO:0030496=PMID:19995937} Q9P2J3 Kelch-like protein 9 protein 20100608 {GO:0000910=IMP, GO:0004842=IDA, GO:0007067=IEA, GO:0016567=IDA, GO:0031463=IDA, GO:0030496=IDA} cytokinesis, mitosis, protein ubiquitination Cul3-RING ubiquitin ligase complex, midbody ubiquitin-protein ligase activity Human KLK1 UniProtKB UniProtKB {GO:0004252=PMID:7749372, GO:0006508=GO_REF:0000037, GO:0005634=PMID:19232384} P06870 Kallikrein-1 protein 20110510 {GO:0004252=NAS, GO:0006508=IEA, GO:0005634=IDA} proteolysis nucleus serine-type endopeptidase activity Human KLK10 PINC UniProtKB {GO:0007049=GO_REF:0000037, GO:0004252=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0008236=PMID:8764136, GO:0005576=GO_REF:0000039} O43240 Kallikrein-10 protein 20030904 {GO:0007049=IEA, GO:0004252=IEA, GO:0006508=IEA, GO:0008236=TAS, GO:0005576=IEA} cell cycle, proteolysis extracellular region serine-type endopeptidase activity, serine-type peptidase activity Human KLK13 UniProtKB UniProtKB {GO:0005515=PMID:14687906, GO:0005737=PMID:12642628, GO:0016787=PMID:14687906, GO:0004252=PMID:10766816, GO:0006508=PMID:10766816, GO:0005576=PMID:10766816} Q9UKR3 Kallikrein-13 protein 20051222 {GO:0005515=IPI, GO:0005737=IDA, GO:0016787=IDA, GO:0004252=NAS, GO:0006508=NAS, GO:0005576=TAS} proteolysis cytoplasm, extracellular region hydrolase activity, protein binding, serine-type endopeptidase activity Human KLK2 BHF-UCL UniProtKB {GO:0022617=Reactome:REACT_118572, GO:0004252=PMID:9042371, GO:0030198=Reactome:REACT_118779, GO:0006508=GO_REF:0000037, GO:0005576=Reactome:REACT_118600} P20151 Kallikrein-2 protein 20111202 {GO:0022617=TAS, GO:0004252=IDA, GO:0030198=TAS, GO:0006508=IEA, GO:0005576=TAS} extracellular matrix disassembly, extracellular matrix organization, proteolysis extracellular region serine-type endopeptidase activity Human KLK3 InterPro UniProtKB {GO:0005515=PMID:1725227, GO:0004252=GO_REF:0000002, GO:0016525=PMID:10675891, GO:0006508=GO_REF:0000002, GO:0008236=PMID:2470553, GO:0005576=Reactome:REACT_15465, GO:0044267=Reactome:REACT_17015} Q8IXI4 Prostate specific antigen protein 20130413 {GO:0005515=IPI, GO:0004252=IEA, GO:0016525=NAS, GO:0006508=IEA, GO:0008236=TAS, GO:0005576=TAS, GO:0044267=TAS} cellular protein metabolic process, negative regulation of angiogenesis, proteolysis extracellular region protein binding, serine-type endopeptidase activity, serine-type peptidase activity Human InterPro:IPR001254|InterPro:IPR001314|InterPro:IPR018114 KLK4 UniProtKB UniProtKB {GO:0004252=GO_REF:0000002, GO:0097186=PMID:15235027, GO:0006508=PMID:10438493, GO:0008236=PMID:10438493, GO:0005576=GO_REF:0000039, GO:0046872=GO_REF:0000037} Q9Y5K2 Kallikrein-4 protein 20120621 {GO:0004252=IEA, GO:0097186=IMP, GO:0006508=NAS, GO:0008236=NAS, GO:0005576=IEA, GO:0046872=IEA} amelogenesis, proteolysis extracellular region metal ion binding, serine-type endopeptidase activity, serine-type peptidase activity Human KLK5 PINC UniProtKB {GO:0005515=PMID:19194479, GO:0045745=PMID:16885167, GO:0008544=PMID:10514489, GO:0004252=PMID:16885167, GO:0006508=GO_REF:0000029, GO:0008236=PMID:10514489, GO:0008233=PMID:10608802, GO:0005576=GO_REF:0000029, GO:0005615=PMID:10608802} Q9Y337 Kallikrein-5 protein 20030904 {GO:0005515=IPI, GO:0045745=IDA, GO:0008544=TAS, GO:0004252=IDA, GO:0006508=NAS, GO:0008236=TAS, GO:0008233=TAS, GO:0005576=NAS, GO:0005615=TAS} epidermis development, positive regulation of G-protein coupled receptor protein signaling pathway, proteolysis extracellular region, extracellular space peptidase activity, protein binding, serine-type endopeptidase activity, serine-type peptidase activity Human KLK6 UniProtKB UniProtKB {GO:0005515=PMID:12878203, GO:0045745=PMID:16885167, GO:0016540=PMID:12878203, GO:0004252=PMID:16885167, GO:0005783=GO_REF:0000037, GO:0042552=PMID:11668196, GO:0009611=PMID:12016211, GO:0005730=GO_REF:0000039, GO:0005576=PMID:11668196, GO:0042982=PMID:12709365, GO:0042246=PMID:12878203, GO:0007417=PMID:12589961, GO:0005739=GO_REF:0000039, GO:0005737=PMID:11668196, GO:0010975=GO_REF:0000019, GO:0030574=PMID:12878203, GO:0006508=GO_REF:0000037, GO:0042445=PMID:11668196, GO:0045595=PMID:11668196} Q92876 Kallikrein-6 protein 20090529 {GO:0005515=IPI, GO:0045745=IDA, GO:0016540=NAS, GO:0004252=IDA, GO:0005783=IEA, GO:0042552=NAS, GO:0009611=NAS, GO:0005730=IEA, GO:0005576=IDA, GO:0042982=NAS, GO:0042246=NAS, GO:0007417=NAS, GO:0005739=IEA, GO:0005737=IDA, GO:0010975=IEA, GO:0030574=NAS, GO:0006508=IEA, GO:0042445=NAS, GO:0045595=NAS} amyloid precursor protein metabolic process, central nervous system development, collagen catabolic process, hormone metabolic process, myelination, positive regulation of G-protein coupled receptor protein signaling pathway, protein autoprocessing, proteolysis, regulation of cell differentiation, regulation of neuron projection development, response to wounding, tissue regeneration cytoplasm, endoplasmic reticulum, extracellular region, mitochondrion, nucleolus protein binding, serine-type endopeptidase activity Human KLK7 PINC UniProtKB {GO:0008544=PMID:8034709, GO:0004252=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0008236=PMID:8034709, GO:0005576=GO_REF:0000039} P49862 Kallikrein-7 protein 20030904 {GO:0008544=TAS, GO:0004252=IEA, GO:0006508=IEA, GO:0008236=TAS, GO:0005576=IEA} epidermis development, proteolysis extracellular region serine-type endopeptidase activity, serine-type peptidase activity Human KLK8 BHF-UCL UniProtKB {GO:0005515=PMID:17761692, GO:0008219=GO_REF:0000024, GO:0004252=PMID:16337200, GO:0009611=GO_REF:0000024, GO:0005615=GO_REF:0000024, GO:0043616=GO_REF:0000024, GO:0005737=PMID:17761692, GO:0050808=GO_REF:0000019, GO:0048681=GO_REF:0000024, GO:0050807=GO_REF:0000024, GO:0048812=GO_REF:0000024, GO:0006508=GO_REF:0000037, GO:0007613=GO_REF:0000024, GO:0031642=GO_REF:0000024} O60259 Kallikrein-8 protein 20110310 {GO:0005515=IPI, GO:0008219=ISS, GO:0004252=IDA, GO:0009611=ISS, GO:0005615=ISS, GO:0043616=ISS, GO:0005737=IDA, GO:0050808=IEA, GO:0048681=ISS, GO:0050807=ISS, GO:0048812=ISS, GO:0006508=IEA, GO:0007613=ISS, GO:0031642=ISS} cell death, keratinocyte proliferation, memory, negative regulation of axon regeneration, negative regulation of myelination, neuron projection morphogenesis, proteolysis, regulation of synapse organization, response to wounding, synapse organization cytoplasm, extracellular space protein binding, serine-type endopeptidase activity Human KLK9 UniProtKB UniProtKB {GO:0004252=PMID:11054574, GO:0006508=GO_REF:0000029, GO:0005576=GO_REF:0000029} Q9UKQ9 Kallikrein-9 protein 20021104 {GO:0004252=NAS, GO:0006508=NAS, GO:0005576=NAS} proteolysis extracellular region serine-type endopeptidase activity Human KLKB1 BHF-UCL UniProtKB {GO:0005515=PMID:2844223, GO:0004252=GO_REF:0000002, GO:0005506=GO_REF:0000002, GO:0005886=Reactome:REACT_2004, GO:0051919=PMID:89876, GO:0009055=GO_REF:0000002, GO:0005576=Reactome:REACT_118776, GO:0005615=PMID:89876, GO:0004497=GO_REF:0000038, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0007596=Reactome:REACT_2051, GO:0002542=PMID:2510163, GO:0007597=Reactome:REACT_326, GO:0006508=GO_REF:0000037, GO:0031639=PMID:89876, GO:0016705=GO_REF:0000002, GO:0042730=GO_REF:0000037, GO:0031638=PMID:2510163, GO:0020037=GO_REF:0000002} P03952 Plasma kallikrein protein 20081015 {GO:0005515=IPI, GO:0004252=IEA, GO:0005506=IEA, GO:0005886=TAS, GO:0051919=IDA, GO:0009055=IEA, GO:0005576=TAS, GO:0005615=IDA, GO:0004497=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0007596=TAS, GO:0002542=TAS, GO:0007597=TAS, GO:0006508=IEA, GO:0031639=IDA, GO:0016705=IEA, GO:0042730=IEA, GO:0031638=TAS, GO:0020037=IEA} Factor XII activation, blood coagulation, blood coagulation, intrinsic pathway, extracellular matrix disassembly, extracellular matrix organization, fibrinolysis, plasminogen activation, positive regulation of fibrinolysis, proteolysis, zymogen activation extracellular region, extracellular space, plasma membrane electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, protein binding, serine-type endopeptidase activity Human KLRB1 PINC UniProtKB {GO:0005886=PMID:8077657, GO:0030246=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007166=PMID:8077657, GO:0004888=PMID:8077657} Q12918 Killer cell lectin-like receptor subfamily B member 1 protein 20030904 {GO:0005886=TAS, GO:0030246=IEA, GO:0016021=IEA, GO:0007166=TAS, GO:0004888=TAS} cell surface receptor signaling pathway integral to membrane, plasma membrane carbohydrate binding, transmembrane signaling receptor activity Human KLRC1 Reactome UniProtKB {GO:0005886=Reactome:REACT_11119, GO:0005887=PMID:2007850, GO:0050776=Reactome:REACT_11152, GO:0030246=GO_REF:0000002, GO:0007166=PMID:2007850, GO:0004888=PMID:2007850} P26715 NKG2-A/NKG2-B type II integral membrane protein protein 20130130 {GO:0005886=TAS, GO:0005887=TAS, GO:0050776=TAS, GO:0030246=IEA, GO:0007166=TAS, GO:0004888=TAS} cell surface receptor signaling pathway, regulation of immune response integral to plasma membrane, plasma membrane carbohydrate binding, transmembrane signaling receptor activity Human KLRC2 IntAct UniProtKB {GO:0005515=PMID:20890284, GO:0007165=PMID:2007850, GO:0006968=PMID:9683661, GO:0005886=Reactome:REACT_147879, GO:0005887=PMID:8436421, GO:0045087=Reactome:REACT_6802, GO:0030246=GO_REF:0000002, GO:0004888=PMID:9683661} P26717 NKG2-C type II integral membrane protein protein 20130415 {GO:0005515=IPI, GO:0007165=TAS, GO:0006968=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0045087=TAS, GO:0030246=IEA, GO:0004888=TAS} cellular defense response, innate immune response, signal transduction integral to plasma membrane, plasma membrane carbohydrate binding, protein binding, transmembrane signaling receptor activity Human UniProtKB:O43914 KLRC3 PINC UniProtKB {GO:0006968=PMID:9683661, GO:0030246=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0004888=PMID:9683661} Q07444 NKG2-E type II integral membrane protein protein 20030904 {GO:0006968=TAS, GO:0030246=IEA, GO:0016021=IEA, GO:0004888=TAS} cellular defense response integral to membrane carbohydrate binding, transmembrane signaling receptor activity Human KLRC4 PINC UniProtKB {GO:0006968=PMID:9683661, GO:0016021=GO_REF:0000037} O43908 NKG2-F type II integral membrane protein protein 20050308 {GO:0006968=TAS, GO:0016021=IEA} cellular defense response integral to membrane Human KLRD1 Reactome UniProtKB {GO:0005886=Reactome:REACT_147879, GO:0045087=Reactome:REACT_6802, GO:0050776=Reactome:REACT_11152, GO:0030246=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007166=PMID:7589107, GO:0009897=GO_REF:0000019, GO:0004888=PMID:7589107} Q13241 Natural killer cells antigen CD94 protein 20130130 {GO:0005886=TAS, GO:0045087=TAS, GO:0050776=TAS, GO:0030246=IEA, GO:0016021=IEA, GO:0007166=TAS, GO:0009897=IEA, GO:0004888=TAS} cell surface receptor signaling pathway, innate immune response, regulation of immune response external side of plasma membrane, integral to membrane, plasma membrane carbohydrate binding, transmembrane signaling receptor activity Human KLRF1 PINC UniProtKB {GO:0016020=PMID:10671213, GO:0005887=PMID:10671213, GO:0030246=GO_REF:0000002, GO:0007166=PMID:10671213, GO:0004888=PMID:10671213, GO:0032393=PMID:10671213} Q9NZS2 Killer cell lectin-like receptor subfamily F member 1 protein 20030904 {GO:0016020=TAS, GO:0005887=TAS, GO:0030246=IEA, GO:0007166=TAS, GO:0004888=TAS, GO:0032393=TAS} cell surface receptor signaling pathway integral to plasma membrane, membrane MHC class I receptor activity, carbohydrate binding, transmembrane signaling receptor activity Human KLRF2 UniProtKB UniProtKB {GO:0005515=PMID:20194751, GO:0050663=PMID:20194751, GO:0043320=PMID:20194751, GO:0005887=PMID:20194751, GO:0030246=GO_REF:0000002, GO:0042803=PMID:20194751} D3W0D1 Killer cell lectin-like receptor subfamily F member 2 protein 20101217 {GO:0005515=IPI, GO:0050663=TAS, GO:0043320=TAS, GO:0005887=IDA, GO:0030246=IEA, GO:0042803=IDA} cytokine secretion, natural killer cell degranulation integral to plasma membrane carbohydrate binding, protein binding, protein homodimerization activity Human UniProtKB:Q6UVW9 KLRG1 Reactome UniProtKB {GO:0006968=PMID:9842918, GO:0006954=PMID:9842918, GO:0005886=GO_REF:0000039, GO:0045087=GO_REF:0000037, GO:0050776=Reactome:REACT_11152, GO:0030246=GO_REF:0000002, GO:0004872=PMID:9765598, GO:0016021=GO_REF:0000037, GO:0007166=PMID:9842918} Q96E93 Killer cell lectin-like receptor subfamily G member 1 protein 20070516 {GO:0006968=TAS, GO:0006954=TAS, GO:0005886=IEA, GO:0045087=IEA, GO:0050776=TAS, GO:0030246=IEA, GO:0004872=TAS, GO:0016021=IEA, GO:0007166=TAS} cell surface receptor signaling pathway, cellular defense response, inflammatory response, innate immune response, regulation of immune response integral to membrane, plasma membrane carbohydrate binding, receptor activity Human KLRK1 ENSEMBL UniProtKB {GO:0032729=GO_REF:0000019, GO:0005515=PMID:15240696, GO:0042288=GO_REF:0000019, GO:0005886=Reactome:REACT_147879, GO:0009986=PMID:10426994, GO:0050830=GO_REF:0000019, GO:0031295=PMID:18676862, GO:0042803=GO_REF:0000019, GO:0045429=GO_REF:0000019, GO:0002223=GO_REF:0000019, GO:0007165=PMID:2007850, GO:0071222=GO_REF:0000019, GO:0030101=GO_REF:0000019, GO:0005887=PMID:2007850, GO:0045087=Reactome:REACT_6802, GO:0050776=Reactome:REACT_11152, GO:0045954=GO_REF:0000019, GO:0030246=GO_REF:0000002, GO:0004872=PMID:2007850, GO:0016021=PMID:9683661, GO:0009897=GO_REF:0000019, GO:0032394=GO_REF:0000019} Q8WZ67 NKG2-D type II integral membrane protein protein 20130413 {GO:0032729=IEA, GO:0005515=IPI, GO:0042288=IEA, GO:0005886=TAS, GO:0009986=IDA, GO:0050830=IEA, GO:0031295=TAS, GO:0042803=IEA, GO:0045429=IEA, GO:0002223=IEA, GO:0007165=TAS, GO:0071222=IEA, GO:0030101=IEA, GO:0005887=TAS, GO:0045087=TAS, GO:0050776=TAS, GO:0045954=IEA, GO:0030246=IEA, GO:0004872=TAS, GO:0016021=TAS, GO:0009897=IEA, GO:0032394=IEA} T cell costimulation, cellular response to lipopolysaccharide, defense response to Gram-positive bacterium, innate immune response, natural killer cell activation, positive regulation of interferon-gamma production, positive regulation of natural killer cell mediated cytotoxicity, positive regulation of nitric oxide biosynthetic process, regulation of immune response, signal transduction, stimulatory C-type lectin receptor signaling pathway cell surface, external side of plasma membrane, integral to membrane, integral to plasma membrane, plasma membrane MHC class I protein binding, MHC class Ib receptor activity, carbohydrate binding, protein binding, protein homodimerization activity, receptor activity Human Ensembl:ENSMUSP00000032252 KMO Reactome UniProtKB {GO:0070189=PMID:10672018, GO:0006569=Reactome:REACT_916, GO:0009651=PMID:10672018, GO:0050660=PMID:10672018, GO:0005743=GO_REF:0000019, GO:0005741=PMID:10672018, GO:0044281=Reactome:REACT_111217, GO:0004502=PMID:10672018, GO:0005829=Reactome:REACT_927, GO:0034641=Reactome:REACT_13, GO:0019805=GO_REF:0000002, GO:0019441=GO_REF:0000019, GO:0016174=PMID:10672018, GO:0016021=GO_REF:0000037, GO:0009435=GO_REF:0000041} O15229 Kynurenine 3-monooxygenase protein 20130301 {GO:0070189=IDA, GO:0006569=TAS, GO:0009651=IDA, GO:0050660=IDA, GO:0005743=IEA, GO:0005741=ISS, GO:0044281=TAS, GO:0004502=IDA, GO:0005829=TAS, GO:0034641=TAS, GO:0019805=IEA, GO:0019441=IEA, GO:0016174=IDA, GO:0016021=IEA, GO:0009435=IEA} NAD biosynthetic process, cellular nitrogen compound metabolic process, kynurenine metabolic process, quinolinate biosynthetic process, response to salt stress, small molecule metabolic process, tryptophan catabolic process, tryptophan catabolic process to kynurenine cytosol, integral to membrane, mitochondrial inner membrane, mitochondrial outer membrane NAD(P)H oxidase activity, flavin adenine dinucleotide binding, kynurenine 3-monooxygenase activity Human KNDC1 UniProtKB UniProtKB {GO:0051056=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0030425=GO_REF:0000019, GO:0005085=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0021707=GO_REF:0000019, GO:0048814=GO_REF:0000019, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0004674=GO_REF:0000019, GO:0001934=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0005088=GO_REF:0000019, GO:0032045=GO_REF:0000019} Q76NI1 Protein very KIND protein 20081107 {GO:0051056=IEA, GO:0007264=IEA, GO:0005575=ND, GO:0030425=IEA, GO:0005085=IEA, GO:0005622=IEA, GO:0021707=IEA, GO:0048814=IEA, GO:0008150=ND, GO:0003674=ND, GO:0004674=IEA, GO:0001934=IEA, GO:0043025=IEA, GO:0005088=IEA, GO:0032045=IEA} biological_process, cerebellar granule cell differentiation, positive regulation of protein phosphorylation, regulation of dendrite morphogenesis, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cellular_component, dendrite, guanyl-nucleotide exchange factor complex, intracellular, neuronal cell body Ras guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, molecular_function, protein serine/threonine kinase activity Human KNG1 IntAct UniProtKB {GO:0005515=PMID:8710908, GO:0004869=GO_REF:0000037, GO:0043065=PMID:12715893, GO:0005886=Reactome:REACT_2239, GO:0005102=PMID:11290596, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_22436, GO:0007204=PMID:16014619, GO:0005615=GO_REF:0000039, GO:0006939=PMID:11385996, GO:0007162=PMID:11970955, GO:0006954=PMID:11385996, GO:0007596=Reactome:REACT_2051, GO:0042311=GO_REF:0000037, GO:0030195=PMID:11970955, GO:0007597=Reactome:REACT_326, GO:0002576=Reactome:REACT_318, GO:0035815=PMID:11385996, GO:0031093=Reactome:REACT_21351, GO:0008270=PMID:12911595, GO:0035810=PMID:11385996, GO:0008201=PMID:12911595} P01042 Kininogen-1 protein 20130415 {GO:0005515=IPI, GO:0004869=IEA, GO:0043065=NAS, GO:0005886=TAS, GO:0005102=IPI, GO:0030168=TAS, GO:0005576=TAS, GO:0007204=IDA, GO:0005615=IEA, GO:0006939=TAS, GO:0007162=IDA, GO:0006954=TAS, GO:0007596=TAS, GO:0042311=IEA, GO:0030195=IDA, GO:0007597=TAS, GO:0002576=TAS, GO:0035815=TAS, GO:0031093=TAS, GO:0008270=NAS, GO:0035810=TAS, GO:0008201=NAS} blood coagulation, blood coagulation, intrinsic pathway, elevation of cytosolic calcium ion concentration, inflammatory response, negative regulation of blood coagulation, negative regulation of cell adhesion, platelet activation, platelet degranulation, positive regulation of apoptotic process, positive regulation of renal sodium excretion, positive regulation of urine volume, smooth muscle contraction, vasodilation extracellular region, extracellular space, plasma membrane, platelet alpha granule lumen cysteine-type endopeptidase inhibitor activity, heparin binding, protein binding, receptor binding, zinc ion binding Human UniProtKB:Q07021 KNTC1 Reactome UniProtKB {GO:0005515=PMID:12686595, GO:0005828=PMID:11146660, GO:0000236=Reactome:REACT_682, GO:0007093=PMID:11146660, GO:0007096=PMID:11146660, GO:0005634=PMID:11146660, GO:0005829=Reactome:REACT_150414, GO:0000922=PMID:11146660, GO:0006461=PMID:11146660, GO:0000087=Reactome:REACT_910, GO:0000777=GO_REF:0000039, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} P50748 Kinetochore-associated protein 1 protein 20130213 {GO:0005515=IPI, GO:0005828=IDA, GO:0000236=TAS, GO:0007093=IDA, GO:0007096=NAS, GO:0005634=NAS, GO:0005829=TAS, GO:0000922=IDA, GO:0006461=NAS, GO:0000087=TAS, GO:0000777=IEA, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, cell division, mitotic anaphase, mitotic cell cycle, mitotic cell cycle checkpoint, mitotic prometaphase, protein complex assembly, regulation of exit from mitosis condensed chromosome kinetochore, cytosol, kinetochore microtubule, nucleus, spindle pole protein binding Human KPNA1 Reactome UniProtKB {GO:0005515=PMID:12011095, GO:0019221=Reactome:REACT_25229, GO:0019058=Reactome:REACT_6167, GO:0006915=Reactome:REACT_578, GO:0005634=GO_REF:0000024, GO:0006606=GO_REF:0000002, GO:0006607=PMID:7754385, GO:0006921=Reactome:REACT_995, GO:0030425=GO_REF:0000024, GO:0005829=Reactome:REACT_115827, GO:0005737=PMID:7754385, GO:0006309=Reactome:REACT_1213, GO:0005643=PMID:8052633, GO:0008565=GO_REF:0000002, GO:0016032=Reactome:REACT_6185, GO:0042307=GO_REF:0000024, GO:0008139=PMID:7754385, GO:0005654=Reactome:REACT_115827, GO:0000018=PMID:8052633, GO:0075733=Reactome:REACT_6248} P52294 Importin subunit alpha-1 protein 20130213 {GO:0005515=IPI, GO:0019221=TAS, GO:0019058=TAS, GO:0006915=TAS, GO:0005634=ISS, GO:0006606=IEA, GO:0006607=TAS, GO:0006921=TAS, GO:0030425=ISS, GO:0005829=TAS, GO:0005737=TAS, GO:0006309=TAS, GO:0005643=TAS, GO:0008565=IEA, GO:0016032=TAS, GO:0042307=ISS, GO:0008139=TAS, GO:0005654=TAS, GO:0000018=TAS, GO:0075733=TAS} NLS-bearing substrate import into nucleus, apoptotic DNA fragmentation, apoptotic process, cellular component disassembly involved in execution phase of apoptosis, cytokine-mediated signaling pathway, intracellular transport of viral material, positive regulation of protein import into nucleus, protein import into nucleus, regulation of DNA recombination, viral infectious cycle, viral reproduction cytoplasm, cytosol, dendrite, nuclear pore, nucleoplasm, nucleus nuclear localization sequence binding, protein binding, protein transporter activity Human KPNA2 BHF-UCL UniProtKB {GO:0005515=PMID:21988832, GO:0042826=PMID:10869435, GO:0019221=Reactome:REACT_25229, GO:0005634=PMID:9020106, GO:0006259=PMID:9168958, GO:0006606=GO_REF:0000002, GO:0006607=PMID:17324944, GO:0005829=Reactome:REACT_115827, GO:0000085=PMID:7565597, GO:0005737=PMID:7754385, GO:0019048=GO_REF:0000037, GO:0008565=GO_REF:0000002, GO:0008139=PMID:17324944, GO:0005654=Reactome:REACT_115827, GO:0000018=PMID:8016130, GO:0000072=PMID:7565597} P52292 Importin subunit alpha-2 protein 20090803 {GO:0005515=IPI, GO:0042826=IPI, GO:0019221=TAS, GO:0005634=TAS, GO:0006259=TAS, GO:0006606=IEA, GO:0006607=IDA, GO:0005829=TAS, GO:0000085=TAS, GO:0005737=TAS, GO:0019048=IEA, GO:0008565=IEA, GO:0008139=IDA, GO:0005654=TAS, GO:0000018=TAS, GO:0000072=TAS} DNA metabolic process, G2 phase of mitotic cell cycle, M phase specific microtubule process, NLS-bearing substrate import into nucleus, cytokine-mediated signaling pathway, protein import into nucleus, regulation of DNA recombination, virus-host interaction cytoplasm, cytosol, nucleoplasm, nucleus histone deacetylase binding, nuclear localization sequence binding, protein binding, protein transporter activity Human UniProtKB:P56524 KPNA3 IntAct UniProtKB {GO:0005515=PMID:15057270, GO:0006461=PMID:9435235, GO:0005643=PMID:9154134, GO:0019221=Reactome:REACT_25229, GO:0008565=GO_REF:0000002, GO:0005654=Reactome:REACT_115827, GO:0008139=PMID:9435235, GO:0008022=GO_REF:0000019, GO:0075732=GO_REF:0000037, GO:0046718=GO_REF:0000037, GO:0006607=PMID:9435235, GO:0005829=Reactome:REACT_115827} O00505 Importin subunit alpha-3 protein 20130415 {GO:0005515=IPI, GO:0006461=TAS, GO:0005643=TAS, GO:0019221=TAS, GO:0008565=IEA, GO:0005654=TAS, GO:0008139=TAS, GO:0008022=IEA, GO:0075732=IEA, GO:0046718=IEA, GO:0006607=TAS, GO:0005829=TAS} NLS-bearing substrate import into nucleus, cytokine-mediated signaling pathway, protein complex assembly, viral entry into host cell, viral penetration into host nucleus cytosol, nuclear pore, nucleoplasm nuclear localization sequence binding, protein C-terminus binding, protein binding, protein transporter activity Human UniProtKB:P46527 KPNA4 Reactome UniProtKB {GO:0019221=Reactome:REACT_25229, GO:0008565=GO_REF:0000019, GO:0005654=Reactome:REACT_115827, GO:0006607=PMID:9395085, GO:0005829=Reactome:REACT_115827} O00629 Importin subunit alpha-4 protein 20130301 {GO:0019221=TAS, GO:0008565=IEA, GO:0005654=TAS, GO:0006607=TAS, GO:0005829=TAS} NLS-bearing substrate import into nucleus, cytokine-mediated signaling pathway cytosol, nucleoplasm protein transporter activity Human KPNA5 InterPro UniProtKB {GO:0005515=PMID:22770219, GO:0005737=GO_REF:0000002, GO:0019221=Reactome:REACT_25229, GO:0008565=GO_REF:0000002, GO:0005634=GO_REF:0000002, GO:0005654=Reactome:REACT_115827, GO:0006606=GO_REF:0000002, GO:0006607=PMID:9395085, GO:0005829=Reactome:REACT_115827} Q5TD90 Importin subunit alpha-6 protein 20130413 {GO:0005515=IPI, GO:0005737=IEA, GO:0019221=TAS, GO:0008565=IEA, GO:0005634=IEA, GO:0005654=TAS, GO:0006606=IEA, GO:0006607=TAS, GO:0005829=TAS} NLS-bearing substrate import into nucleus, cytokine-mediated signaling pathway, protein import into nucleus cytoplasm, cytosol, nucleoplasm, nucleus protein binding, protein transporter activity Human InterPro:IPR002652 KPNA6 PINC UniProtKB {GO:0005737=GO_REF:0000002, GO:0008565=GO_REF:0000019, GO:0005634=GO_REF:0000002, GO:0006606=GO_REF:0000019, GO:0006607=PMID:9395085} O60684 Importin subunit alpha-7 protein 20030904 {GO:0005737=IEA, GO:0008565=IEA, GO:0005634=IEA, GO:0006606=IEA, GO:0006607=TAS} NLS-bearing substrate import into nucleus, protein import into nucleus cytoplasm, nucleus protein transporter activity Human KPNA7 Reactome UniProtKB {GO:0019221=Reactome:REACT_25229, GO:0008565=GO_REF:0000002, GO:0005654=Reactome:REACT_115827, GO:0006606=GO_REF:0000002, GO:0005829=Reactome:REACT_115827} A9QM74 Importin subunit alpha-8 protein 20130301 {GO:0019221=TAS, GO:0008565=IEA, GO:0005654=TAS, GO:0006606=IEA, GO:0005829=TAS} cytokine-mediated signaling pathway, protein import into nucleus cytosol, nucleoplasm protein transporter activity Human KPNB1 HPA UniProtKB {GO:0005515=PMID:15494309, GO:0031965=GO_REF:0000052, GO:0019221=Reactome:REACT_25229, GO:0019904=PMID:11984006, GO:0019058=Reactome:REACT_6167, GO:0006915=Reactome:REACT_578, GO:0044281=Reactome:REACT_111217, GO:0006606=PMID:15964792, GO:0006607=PMID:7627554, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_147887, GO:0006913=GO_REF:0000002, GO:0043234=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0006610=PMID:9687515, GO:0006309=Reactome:REACT_1213, GO:0005643=GO_REF:0000002, GO:0008565=GO_REF:0000019, GO:0016032=Reactome:REACT_6185, GO:0008139=PMID:7627554, GO:0005654=Reactome:REACT_147887, GO:0008270=PMID:7615630, GO:0075733=Reactome:REACT_6248, GO:0000060=PMID:7615630} Q14974 Importin subunit beta-1 protein 20111111 {GO:0005515=IPI, GO:0031965=IDA, GO:0019221=TAS, GO:0019904=IPI, GO:0019058=TAS, GO:0006915=TAS, GO:0044281=TAS, GO:0006606=IDA, GO:0006607=TAS, GO:0006921=TAS, GO:0005829=TAS, GO:0006913=IEA, GO:0043234=IEA, GO:0005737=IDA, GO:0006610=IDA, GO:0006309=TAS, GO:0005643=IEA, GO:0008565=IEA, GO:0016032=TAS, GO:0008139=TAS, GO:0005654=TAS, GO:0008270=TAS, GO:0075733=TAS, GO:0000060=TAS} NLS-bearing substrate import into nucleus, apoptotic DNA fragmentation, apoptotic process, cellular component disassembly involved in execution phase of apoptosis, cytokine-mediated signaling pathway, intracellular transport of viral material, nucleocytoplasmic transport, protein import into nucleus, protein import into nucleus, translocation, ribosomal protein import into nucleus, small molecule metabolic process, viral infectious cycle, viral reproduction cytoplasm, cytosol, nuclear membrane, nuclear pore, nucleoplasm, protein complex nuclear localization sequence binding, protein binding, protein domain specific binding, protein transporter activity, zinc ion binding Human KPRP UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q5T749 Keratinocyte proline-rich protein protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 KPTN PINC UniProtKB {GO:0048471=GO_REF:0000039, GO:0005815=PMID:1372044, GO:0007605=PMID:10099934, GO:0006928=PMID:10099934, GO:0032420=GO_REF:0000039, GO:0007015=PMID:10099934, GO:0005634=PMID:1372044, GO:0003779=GO_REF:0000037, GO:0015629=PMID:10099934, GO:0030426=GO_REF:0000039} Q9Y664 Kaptin protein 20030904 {GO:0048471=IEA, GO:0005815=TAS, GO:0007605=NAS, GO:0006928=TAS, GO:0032420=IEA, GO:0007015=TAS, GO:0005634=TAS, GO:0003779=IEA, GO:0015629=TAS, GO:0030426=IEA} actin filament organization, cellular component movement, sensory perception of sound actin cytoskeleton, growth cone, microtubule organizing center, nucleus, perinuclear region of cytoplasm, stereocilium actin binding Human KRAS BHF-UCL UniProtKB {GO:0005515=PMID:12732644, GO:0008286=Reactome:REACT_498, GO:0008284=GO_REF:0000019, GO:0030036=GO_REF:0000019, GO:0005886=Reactome:REACT_147697, GO:0035022=GO_REF:0000019, GO:0007264=Reactome:REACT_12077, GO:0019221=GO_REF:0000019, GO:0003924=GO_REF:0000002, GO:0007265=Reactome:REACT_12033, GO:0050900=Reactome:REACT_12051, GO:0005739=GO_REF:0000019, GO:0000186=Reactome:REACT_12005, GO:0043524=GO_REF:0000019, GO:0051092=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0007411=Reactome:REACT_18266, GO:0043406=GO_REF:0000019, GO:0000165=Reactome:REACT_634, GO:0030275=GO_REF:0000019, GO:0048169=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0051385=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0005525=GO_REF:0000037, GO:0010628=PMID:22065586, GO:0016020=GO_REF:0000002, GO:0051000=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0032228=GO_REF:0000019, GO:0008542=GO_REF:0000019, GO:0035176=GO_REF:0000019, GO:0001934=PMID:22065586, GO:0045121=GO_REF:0000019, GO:0019003=GO_REF:0000019, GO:0019002=GO_REF:0000019, GO:0051146=GO_REF:0000019} P01116 GTPase KRas protein 20111212 {GO:0005515=IPI, GO:0008286=TAS, GO:0008284=IEA, GO:0030036=IEA, GO:0005886=TAS, GO:0035022=IEA, GO:0007264=TAS, GO:0019221=IEA, GO:0003924=IEA, GO:0007265=TAS, GO:0050900=TAS, GO:0005739=IEA, GO:0000186=TAS, GO:0043524=IEA, GO:0051092=IEA, GO:0007173=TAS, GO:0007411=TAS, GO:0043406=IEA, GO:0000165=TAS, GO:0030275=IEA, GO:0048169=IEA, GO:0048011=TAS, GO:0051385=IEA, GO:0051384=IEA, GO:0005525=IEA, GO:0010628=IMP, GO:0016020=IEA, GO:0051000=IEA, GO:0008543=TAS, GO:0007596=TAS, GO:0045087=TAS, GO:0032228=IEA, GO:0008542=IEA, GO:0035176=IEA, GO:0001934=IMP, GO:0045121=IEA, GO:0019003=IEA, GO:0019002=IEA, GO:0051146=IEA} MAPK cascade, Ras protein signal transduction, actin cytoskeleton organization, activation of MAPKK activity, axon guidance, blood coagulation, cytokine-mediated signaling pathway, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, leukocyte migration, negative regulation of neuron apoptotic process, neurotrophin TRK receptor signaling pathway, positive regulation of MAP kinase activity, positive regulation of NF-kappaB transcription factor activity, positive regulation of Rac protein signal transduction, positive regulation of cell proliferation, positive regulation of gene expression, positive regulation of nitric-oxide synthase activity, positive regulation of protein phosphorylation, regulation of long-term neuronal synaptic plasticity, regulation of synaptic transmission, GABAergic, response to glucocorticoid stimulus, response to mineralocorticoid stimulus, small GTPase mediated signal transduction, social behavior, striated muscle cell differentiation, visual learning membrane, membrane raft, mitochondrion, plasma membrane GDP binding, GMP binding, GTP binding, GTPase activity, LRR domain binding, protein binding Human KRBA1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} A5PL33 Protein KRBA1 protein 20090706 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human KRCC1 null null {} null null null null {} null null null KREMEN1 BHF-UCL UniProtKB {GO:0005515=PMID:17804805, GO:0007154=PMID:11267660, GO:0016020=PMID:11267660, GO:0016021=GO_REF:0000037, GO:0016055=GO_REF:0000037, GO:0060828=PMID:17804805} Q96MU8 Kremen protein 1 protein 20100930 {GO:0005515=IPI, GO:0007154=TAS, GO:0016020=TAS, GO:0016021=IEA, GO:0016055=IEA, GO:0060828=NAS} Wnt receptor signaling pathway, cell communication, regulation of canonical Wnt receptor signaling pathway integral to membrane, membrane protein binding Human UniProtKB:O94907 KREMEN2 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0016055=GO_REF:0000037} Q8NCW0 Kremen protein 2 protein 20130413 {GO:0016021=IEA, GO:0016055=IEA} Wnt receptor signaling pathway integral to membrane Human UniProtKB-KW:KW-0879 KRI1 null null {} null null null null {} null null null KRIT1 IntAct UniProtKB {GO:0005515=PMID:17657516, GO:0005886=GO_REF:0000039, GO:0007264=PMID:9285558, GO:2000114=PMID:20332120, GO:0001525=GO_REF:0000037, GO:0032092=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0010596=PMID:20616044, GO:0005083=PMID:9285558, GO:0005737=GO_REF:0000037, GO:0005911=PMID:20332120, GO:0001937=PMID:20616044, GO:0016525=PMID:20616044, GO:0045454=PMID:20668652, GO:2000352=PMID:20616044, GO:0005856=GO_REF:0000039} O00522 Krev interaction trapped protein 1 protein 20130415 {GO:0005515=IPI, GO:0005886=IEA, GO:0007264=TAS, GO:2000114=IMP, GO:0001525=IEA, GO:0032092=IEA, GO:0043234=IEA, GO:0010596=IMP, GO:0005083=TAS, GO:0005737=IEA, GO:0005911=IDA, GO:0001937=IMP, GO:0016525=IMP, GO:0045454=IMP, GO:2000352=IMP, GO:0005856=IEA} angiogenesis, cell redox homeostasis, negative regulation of angiogenesis, negative regulation of endothelial cell apoptotic process, negative regulation of endothelial cell migration, negative regulation of endothelial cell proliferation, positive regulation of protein binding, regulation of establishment of cell polarity, small GTPase mediated signal transduction cell-cell junction, cytoplasm, cytoskeleton, plasma membrane, protein complex protein binding, small GTPase regulator activity Human UniProtKB:Q9BSQ5 KRR1 HPA UniProtKB {GO:0005737=GO_REF:0000039, GO:0030529=GO_REF:0000037, GO:0006364=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q13601 KRR1 small subunit processome component homolog protein 20111111 {GO:0005737=IEA, GO:0030529=IEA, GO:0006364=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA} rRNA processing cytoplasm, nucleolus, nucleus, ribonucleoprotein complex RNA binding Human KRT1 PINC UniProtKB {GO:0005515=PMID:11290596, GO:0005882=PMID:1380725, GO:0005886=GO_REF:0000039, GO:0045765=PMID:11290596, GO:0001867=PMID:11549596, GO:0016020=PMID:11290596, GO:0008544=PMID:1380725, GO:0005200=PMID:1380725, GO:0030246=PMID:11549596, GO:0004872=PMID:11290596, GO:0045095=GO_REF:0000019, GO:0005856=PMID:1381288, GO:0006979=PMID:11549596, GO:0042730=PMID:11290596} P04264 Keratin, type II cytoskeletal 1 protein 20030904 {GO:0005515=IPI, GO:0005882=TAS, GO:0005886=IEA, GO:0045765=NAS, GO:0001867=IPI, GO:0016020=IDA, GO:0008544=TAS, GO:0005200=TAS, GO:0030246=IPI, GO:0004872=NAS, GO:0045095=IEA, GO:0005856=TAS, GO:0006979=NAS, GO:0042730=NAS} complement activation, lectin pathway, epidermis development, fibrinolysis, regulation of angiogenesis, response to oxidative stress cytoskeleton, intermediate filament, keratin filament, membrane, plasma membrane carbohydrate binding, protein binding, receptor activity, structural constituent of cytoskeleton Human KRT10 PINC UniProtKB {GO:0005882=PMID:2459124, GO:0008544=PMID:1380725, GO:0005198=PMID:1380725, GO:0071277=GO_REF:0000019, GO:0045095=GO_REF:0000019, GO:0030280=PMID:2459124} P13645 Keratin, type I cytoskeletal 10 protein 20030904 {GO:0005882=NAS, GO:0008544=TAS, GO:0005198=TAS, GO:0071277=IEA, GO:0045095=IEA, GO:0030280=NAS} cellular response to calcium ion, epidermis development intermediate filament, keratin filament structural constituent of epidermis, structural molecule activity Human KRT12 PINC UniProtKB {GO:0061303=GO_REF:0000019, GO:0005882=GO_REF:0000037, GO:0060429=GO_REF:0000019, GO:0005198=GO_REF:0000002, GO:0007601=PMID:9171831} Q99456 Keratin, type I cytoskeletal 12 protein 20030904 {GO:0061303=IEA, GO:0005882=IEA, GO:0060429=IEA, GO:0005198=IEA, GO:0007601=TAS} cornea development in camera-type eye, epithelium development, visual perception intermediate filament structural molecule activity Human KRT13 PINC UniProtKB {GO:0009314=GO_REF:0000019, GO:0005882=GO_REF:0000038, GO:0008544=PMID:7493031, GO:0071300=GO_REF:0000019, GO:0005198=GO_REF:0000002, GO:0045095=PMID:9714826, GO:0043587=GO_REF:0000019} P13646 Keratin, type I cytoskeletal 13 protein 20030904 {GO:0009314=IEA, GO:0005882=IEA, GO:0008544=TAS, GO:0071300=IEA, GO:0005198=IEA, GO:0045095=IDA, GO:0043587=IEA} cellular response to retinoic acid, epidermis development, response to radiation, tongue morphogenesis intermediate filament, keratin filament structural molecule activity Human KRT14 BHF-UCL UniProtKB {GO:0005882=PMID:10852826, GO:0005515=PMID:15731013, GO:0034329=Reactome:REACT_20676, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0010043=GO_REF:0000019, GO:0071944=GO_REF:0000019, GO:0005829=Reactome:REACT_20615, GO:0005737=GO_REF:0000052, GO:0008544=PMID:7525408, GO:0010212=GO_REF:0000019, GO:0030855=GO_REF:0000019, GO:0005200=PMID:7525408, GO:0031581=Reactome:REACT_20537, GO:0045110=PMID:11724817, GO:0045095=PMID:7679677} P02533 Keratin, type I cytoskeletal 14 protein 20120928 {GO:0005882=IDA, GO:0005515=IPI, GO:0034329=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0010043=IEA, GO:0071944=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0008544=TAS, GO:0010212=IEA, GO:0030855=IEA, GO:0005200=TAS, GO:0031581=TAS, GO:0045110=IMP, GO:0045095=IDA} cell junction assembly, epidermis development, epithelial cell differentiation, hemidesmosome assembly, intermediate filament bundle assembly, response to ionizing radiation, response to zinc ion cell periphery, cytoplasm, cytosol, intermediate filament, keratin filament, nucleolus, nucleus protein binding, structural constituent of cytoskeleton Human KRT15 BHF-UCL UniProtKB {GO:0005515=PMID:16189514, GO:0005882=GO_REF:0000037, GO:0008544=PMID:2452170, GO:0005198=GO_REF:0000002, GO:0097110=PMID:10852826, GO:0005200=PMID:2580298} P19012 Keratin, type I cytoskeletal 15 protein 20120928 {GO:0005515=IPI, GO:0005882=IEA, GO:0008544=TAS, GO:0005198=IEA, GO:0097110=IPI, GO:0005200=TAS} epidermis development intermediate filament protein binding, scaffold protein binding, structural constituent of cytoskeleton, structural molecule activity Human UniProtKB:Q99959 KRT16 HGNC UniProtKB {GO:0005515=PMID:15731013, GO:0005882=PMID:2451124, GO:0008544=PMID:7539673, GO:0008283=PMID:8595410, GO:0005198=GO_REF:0000002, GO:0045104=GO_REF:0000019, GO:0007010=PMID:2451124, GO:0005200=PMID:2451124} P08779 Keratin, type I cytoskeletal 16 protein 20060206 {GO:0005515=IPI, GO:0005882=NAS, GO:0008544=TAS, GO:0008283=TAS, GO:0005198=IEA, GO:0045104=IEA, GO:0007010=NAS, GO:0005200=NAS} cell proliferation, cytoskeleton organization, epidermis development, intermediate filament cytoskeleton organization intermediate filament protein binding, structural constituent of cytoskeleton, structural molecule activity Human UniProtKB:Q9BT92 KRT17 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0005882=GO_REF:0000037, GO:0042289=PMID:15795121, GO:0045109=GO_REF:0000019, GO:0030307=GO_REF:0000019, GO:0031424=GO_REF:0000019, GO:0045727=GO_REF:0000019, GO:0071944=GO_REF:0000019, GO:0007165=PMID:15795121, GO:0051798=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0008544=PMID:7539673, GO:0005198=GO_REF:0000002, GO:0005200=PMID:1281771, GO:0002009=GO_REF:0000019, GO:0032395=PMID:15795121} Q04695 Keratin, type I cytoskeletal 17 protein 20130415 {GO:0005515=IPI, GO:0005882=IEA, GO:0042289=IPI, GO:0045109=IEA, GO:0030307=IEA, GO:0031424=IEA, GO:0045727=IEA, GO:0071944=IEA, GO:0007165=IMP, GO:0051798=IEA, GO:0005737=IEA, GO:0008544=TAS, GO:0005198=IEA, GO:0005200=TAS, GO:0002009=IEA, GO:0032395=IDA} epidermis development, intermediate filament organization, keratinization, morphogenesis of an epithelium, positive regulation of cell growth, positive regulation of hair follicle development, positive regulation of translation, signal transduction cell periphery, cytoplasm, intermediate filament MHC class II protein binding, MHC class II receptor activity, protein binding, structural constituent of cytoskeleton, structural molecule activity Human UniProtKB:Q15834 KRT18 BHF-UCL UniProtKB {GO:0005882=PMID:10852826, GO:0005515=PMID:21988832, GO:0048471=GO_REF:0000039, GO:0043066=PMID:11684708, GO:0005815=PMID:18000879, GO:0034451=PMID:18000879, GO:0005730=GO_REF:0000039, GO:0006915=GO_REF:0000019, GO:0009653=PMID:2434380, GO:0033209=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0007049=GO_REF:0000037, GO:0005198=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0097110=PMID:10852826, GO:0045095=PMID:16424149, GO:0043000=PMID:15529338} P05783 Keratin, type I cytoskeletal 18 protein 20120928 {GO:0005882=IDA, GO:0005515=IPI, GO:0048471=IEA, GO:0043066=IDA, GO:0005815=IDA, GO:0034451=IDA, GO:0005730=IEA, GO:0006915=IEA, GO:0009653=TAS, GO:0033209=IEA, GO:0005737=IDA, GO:0007049=IEA, GO:0005198=IEA, GO:0019048=IEA, GO:0097110=IPI, GO:0045095=IDA, GO:0043000=IDA} Golgi to plasma membrane CFTR protein transport, anatomical structure morphogenesis, apoptotic process, cell cycle, negative regulation of apoptotic process, tumor necrosis factor-mediated signaling pathway, virus-host interaction centriolar satellite, cytoplasm, intermediate filament, keratin filament, microtubule organizing center, nucleolus, perinuclear region of cytoplasm protein binding, scaffold protein binding, structural molecule activity Human KRT19 IntAct UniProtKB {GO:0005882=GO_REF:0000037, GO:0005515=PMID:16000376, GO:0030018=GO_REF:0000019, GO:0043627=PMID:10037815, GO:0060706=GO_REF:0000019, GO:0045214=PMID:16000376, GO:0032403=GO_REF:0000019, GO:0071944=PMID:19185580, GO:0042383=GO_REF:0000019, GO:0016010=GO_REF:0000019, GO:0005198=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0005200=PMID:2448790, GO:0043034=PMID:16000376, GO:0008307=PMID:16000376} P08727 Keratin, type I cytoskeletal 19 protein 20130415 {GO:0005882=IEA, GO:0005515=IPI, GO:0030018=IEA, GO:0043627=IEP, GO:0060706=IEA, GO:0045214=IDA, GO:0032403=IEA, GO:0071944=IDA, GO:0042383=IEA, GO:0016010=IEA, GO:0005198=IEA, GO:0019048=IEA, GO:0005200=TAS, GO:0043034=IDA, GO:0008307=IDA} cell differentiation involved in embryonic placenta development, response to estrogen stimulus, sarcomere organization, virus-host interaction Z disc, cell periphery, costamere, dystrophin-associated glycoprotein complex, intermediate filament, sarcolemma protein binding, protein complex binding, structural constituent of cytoskeleton, structural constituent of muscle, structural molecule activity Human UniProtKB:P11532 KRT2 HPA UniProtKB {GO:0005882=PMID:1380918, GO:0032980=PMID:12598329, GO:0051546=PMID:15737202, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0008544=PMID:7524919, GO:0005200=PMID:1380918, GO:0031424=PMID:12598329, GO:0045111=GO_REF:0000052, GO:0045095=GO_REF:0000002, GO:0043616=PMID:12598329} P35908 Keratin, type II cytoskeletal 2 epidermal protein 20100326 {GO:0005882=TAS, GO:0032980=IDA, GO:0051546=IDA, GO:0005737=IDA, GO:0005794=IDA, GO:0008544=TAS, GO:0005200=TAS, GO:0031424=IDA, GO:0045111=IDA, GO:0045095=IEA, GO:0043616=IDA} epidermis development, keratinization, keratinocyte activation, keratinocyte migration, keratinocyte proliferation Golgi apparatus, cytoplasm, intermediate filament, intermediate filament cytoskeleton, keratin filament structural constituent of cytoskeleton Human KRT20 UniProtKB UniProtKB {GO:0005515=PMID:16608857, GO:0005882=PMID:8359595, GO:0005737=PMID:10973561, GO:0045109=PMID:12857878, GO:0005200=PMID:8359595, GO:0050708=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0033554=GO_REF:0000019} P35900 Keratin, type I cytoskeletal 20 protein 20070927 {GO:0005515=IPI, GO:0005882=NAS, GO:0005737=IDA, GO:0045109=IMP, GO:0005200=NAS, GO:0050708=IEA, GO:0006915=IEA, GO:0033554=IEA} apoptotic process, cellular response to stress, intermediate filament organization, regulation of protein secretion cytoplasm, intermediate filament protein binding, structural constituent of cytoskeleton Human KRT23 UniProtKB UniProtKB {GO:0005882=GO_REF:0000037, GO:0005198=GO_REF:0000002} Q9C075 Keratin, type I cytoskeletal 23 protein 20130413 {GO:0005882=IEA, GO:0005198=IEA} intermediate filament structural molecule activity Human UniProtKB-KW:KW-0416 KRT24 HPA UniProtKB {GO:0005882=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0005198=GO_REF:0000002, GO:0045111=GO_REF:0000052} Q2M2I5 Keratin, type I cytoskeletal 24 protein 20101115 {GO:0005882=IEA, GO:0005737=IDA, GO:0005198=IEA, GO:0045111=IDA} cytoplasm, intermediate filament, intermediate filament cytoskeleton structural molecule activity Human KRT25 UniProtKB UniProtKB {GO:0005882=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0045109=GO_REF:0000019, GO:0005198=GO_REF:0000002, GO:0031069=GO_REF:0000019} Q7Z3Z0 Keratin, type I cytoskeletal 25 protein 20130413 {GO:0005882=IEA, GO:0005737=IEA, GO:0045109=IEA, GO:0005198=IEA, GO:0031069=IEA} hair follicle morphogenesis, intermediate filament organization cytoplasm, intermediate filament structural molecule activity Human UniProtKB-SubCell:SL-0086 KRT26 UniProtKB UniProtKB {GO:0005882=GO_REF:0000037, GO:0005198=GO_REF:0000002} Q7Z3Y9 Keratin, type I cytoskeletal 26 protein 20130413 {GO:0005882=IEA, GO:0005198=IEA} intermediate filament structural molecule activity Human UniProtKB-KW:KW-0416 KRT27 UniProtKB UniProtKB {GO:0005882=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0005198=GO_REF:0000002, GO:0031069=GO_REF:0000019} Q7Z3Y8 Keratin, type I cytoskeletal 27 protein 20130413 {GO:0005882=IEA, GO:0005737=IEA, GO:0005198=IEA, GO:0031069=IEA} hair follicle morphogenesis cytoplasm, intermediate filament structural molecule activity Human UniProtKB-SubCell:SL-0086 KRT28 UniProtKB UniProtKB {GO:0005882=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0005198=GO_REF:0000002} Q7Z3Y7 Keratin, type I cytoskeletal 28 protein 20130413 {GO:0005882=IEA, GO:0005737=IEA, GO:0005198=IEA} cytoplasm, intermediate filament structural molecule activity Human UniProtKB-SubCell:SL-0086 KRT3 UniProtKB UniProtKB {GO:0005882=PMID:9171831, GO:0005198=PMID:9171831, GO:0045104=PMID:9171831, GO:0030855=GO_REF:0000024, GO:0007010=GO_REF:0000029, GO:0045095=PMID:9171831} P12035 Keratin, type II cytoskeletal 3 protein 20060407 {GO:0005882=NAS, GO:0005198=IMP, GO:0045104=IMP, GO:0030855=ISS, GO:0007010=NAS, GO:0045095=TAS} cytoskeleton organization, epithelial cell differentiation, intermediate filament cytoskeleton organization intermediate filament, keratin filament structural molecule activity Human KRT31 PINC UniProtKB {GO:0005882=GO_REF:0000037, GO:0008544=PMID:7578244, GO:0005200=PMID:9405442} Q15323 Keratin, type I cuticular Ha1 protein 20030904 {GO:0005882=IEA, GO:0008544=TAS, GO:0005200=TAS} epidermis development intermediate filament structural constituent of cytoskeleton Human KRT32 PINC UniProtKB {GO:0005882=GO_REF:0000037, GO:0008544=PMID:7556444, GO:0005198=GO_REF:0000002} Q14532 Keratin, type I cuticular Ha2 protein 20030904 {GO:0005882=IEA, GO:0008544=TAS, GO:0005198=IEA} epidermis development intermediate filament structural molecule activity Human KRT33A UniProtKB UniProtKB {GO:0005882=GO_REF:0000037, GO:0005198=GO_REF:0000002} O76009 Keratin, type I cuticular Ha3-I protein 20130413 {GO:0005882=IEA, GO:0005198=IEA} intermediate filament structural molecule activity Human UniProtKB-KW:KW-0416 KRT33B UniProtKB UniProtKB {GO:0005882=GO_REF:0000037, GO:0005198=GO_REF:0000002} Q14525 Keratin, type I cuticular Ha3-II protein 20130413 {GO:0005882=IEA, GO:0005198=IEA} intermediate filament structural molecule activity Human UniProtKB-KW:KW-0416 KRT34 PINC UniProtKB {GO:0005882=GO_REF:0000037, GO:0008544=PMID:9756910, GO:0005198=GO_REF:0000002} O76011 Keratin, type I cuticular Ha4 protein 20030904 {GO:0005882=IEA, GO:0008544=TAS, GO:0005198=IEA} epidermis development intermediate filament structural molecule activity Human KRT35 PINC UniProtKB {GO:0005882=GO_REF:0000037, GO:0005198=GO_REF:0000002, GO:0009653=PMID:8823373} Q92764 Keratin, type I cuticular Ha5 protein 20031119 {GO:0005882=IEA, GO:0005198=IEA, GO:0009653=TAS} anatomical structure morphogenesis intermediate filament structural molecule activity Human KRT36 UniProtKB UniProtKB {GO:0005882=GO_REF:0000037, GO:0008150=GO_REF:0000015, GO:0045616=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0030280=PMID:9756910} O76013 Keratin, type I cuticular Ha6 protein 20061026 {GO:0005882=IEA, GO:0008150=ND, GO:0045616=IEA, GO:0005575=ND, GO:0030280=NAS} biological_process, regulation of keratinocyte differentiation cellular_component, intermediate filament structural constituent of epidermis Human KRT37 UniProtKB UniProtKB {GO:0005882=GO_REF:0000037, GO:0005198=GO_REF:0000002} O76014 Keratin, type I cuticular Ha7 protein 20130413 {GO:0005882=IEA, GO:0005198=IEA} intermediate filament structural molecule activity Human UniProtKB-KW:KW-0416 KRT38 UniProtKB UniProtKB {GO:0005882=GO_REF:0000037, GO:0005198=GO_REF:0000002} O76015 Keratin, type I cuticular Ha8 protein 20130413 {GO:0005882=IEA, GO:0005198=IEA} intermediate filament structural molecule activity Human UniProtKB-KW:KW-0416 KRT4 UniProtKB UniProtKB {GO:0005882=PMID:2452170, GO:0005198=GO_REF:0000029, GO:0030855=GO_REF:0000024, GO:0007010=PMID:2452170, GO:0050680=GO_REF:0000024, GO:0045095=GO_REF:0000002} P19013 Keratin, type II cytoskeletal 4 protein 20060118 {GO:0005882=NAS, GO:0005198=NAS, GO:0030855=ISS, GO:0007010=NAS, GO:0050680=ISS, GO:0045095=IEA} cytoskeleton organization, epithelial cell differentiation, negative regulation of epithelial cell proliferation intermediate filament, keratin filament structural molecule activity Human UniProtKB:P07744 KRT5 BHF-UCL UniProtKB {GO:0005882=PMID:10852826, GO:0005515=PMID:15731013, GO:0005739=GO_REF:0000019, GO:0008544=PMID:7520042, GO:0005886=GO_REF:0000019, GO:0005198=GO_REF:0000002, GO:0034329=Reactome:REACT_20676, GO:0097110=PMID:10852826, GO:0031581=Reactome:REACT_20537, GO:0005200=PMID:7520042, GO:0045095=PMID:7679677, GO:0005829=Reactome:REACT_20615} P13647 Keratin, type II cytoskeletal 5 protein 20120928 {GO:0005882=IDA, GO:0005515=IPI, GO:0005739=IEA, GO:0008544=TAS, GO:0005886=IEA, GO:0005198=IEA, GO:0034329=TAS, GO:0097110=IPI, GO:0031581=TAS, GO:0005200=TAS, GO:0045095=IDA, GO:0005829=TAS} cell junction assembly, epidermis development, hemidesmosome assembly cytosol, intermediate filament, keratin filament, mitochondrion, plasma membrane protein binding, scaffold protein binding, structural constituent of cytoskeleton, structural molecule activity Human KRT6A IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0005882=PMID:2410904, GO:0008284=PMID:7543104, GO:0005200=PMID:7543104, GO:0007398=PMID:7545493, GO:0045095=GO_REF:0000002, GO:0030154=PMID:7543104} P02538 Keratin, type II cytoskeletal 6A protein 20130415 {GO:0005515=IPI, GO:0005882=TAS, GO:0008284=NAS, GO:0005200=NAS, GO:0007398=TAS, GO:0045095=IEA, GO:0030154=NAS} cell differentiation, ectoderm development, positive regulation of cell proliferation intermediate filament, keratin filament protein binding, structural constituent of cytoskeleton Human UniProtKB:Q15834 KRT6B PINC UniProtKB {GO:0005200=PMID:9618173, GO:0007398=PMID:9618173, GO:0045095=GO_REF:0000002} P04259 Keratin, type II cytoskeletal 6B protein 20030904 {GO:0005200=TAS, GO:0007398=TAS, GO:0045095=IEA} ectoderm development keratin filament structural constituent of cytoskeleton Human KRT6C UniProtKB UniProtKB {GO:0005882=PMID:9054461, GO:0005198=GO_REF:0000029, GO:0007010=GO_REF:0000029, GO:0045095=GO_REF:0000002} P48668 Keratin, type II cytoskeletal 6C protein 20010924 {GO:0005882=NAS, GO:0005198=NAS, GO:0007010=NAS, GO:0045095=IEA} cytoskeleton organization intermediate filament, keratin filament structural molecule activity Human KRT7 HPA UniProtKB {GO:0005515=PMID:11169732, GO:0005882=PMID:2415537, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0005198=GO_REF:0000029, GO:0019048=GO_REF:0000037, GO:0007010=GO_REF:0000029, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0045095=GO_REF:0000002, GO:0006417=PMID:12072504} P08729 Keratin, type II cytoskeletal 7 protein 20101115 {GO:0005515=IPI, GO:0005882=NAS, GO:0005737=IDA, GO:0005794=IDA, GO:0005198=NAS, GO:0019048=IEA, GO:0007010=NAS, GO:0005730=IDA, GO:0005634=IDA, GO:0045095=IEA, GO:0006417=IDA} cytoskeleton organization, regulation of translation, virus-host interaction Golgi apparatus, cytoplasm, intermediate filament, keratin filament, nucleolus, nucleus protein binding, structural molecule activity Human KRT71 ENSEMBL UniProtKB {GO:0005198=GO_REF:0000002, GO:0045095=GO_REF:0000019, GO:0031069=GO_REF:0000019} Q3SY84 Keratin, type II cytoskeletal 71 protein 20130413 {GO:0005198=IEA, GO:0045095=IEA, GO:0031069=IEA} hair follicle morphogenesis keratin filament structural molecule activity Human Ensembl:ENSMUSP00000023710 KRT72 InterPro UniProtKB {GO:0005198=GO_REF:0000002, GO:0045095=GO_REF:0000002} Q14CN4 Keratin, type II cytoskeletal 72 protein 20130413 {GO:0005198=IEA, GO:0045095=IEA} keratin filament structural molecule activity Human InterPro:IPR003054 KRT73 InterPro UniProtKB {GO:0005198=GO_REF:0000002, GO:0045095=GO_REF:0000002} Q86Y46 Keratin, type II cytoskeletal 73 protein 20130413 {GO:0005198=IEA, GO:0045095=IEA} keratin filament structural molecule activity Human InterPro:IPR003054 KRT74 InterPro UniProtKB {GO:0005198=GO_REF:0000002, GO:0045095=GO_REF:0000002} Q7RTS7 Keratin, type II cytoskeletal 74 protein 20130413 {GO:0005198=IEA, GO:0045095=IEA} keratin filament structural molecule activity Human InterPro:IPR003054 KRT75 InterPro UniProtKB {GO:0005198=GO_REF:0000002, GO:0045095=GO_REF:0000002} O95678 Keratin, type II cytoskeletal 75 protein 20130413 {GO:0005198=IEA, GO:0045095=IEA} keratin filament structural molecule activity Human InterPro:IPR003054 KRT76 HPA UniProtKB {GO:0005882=PMID:1282112, GO:0005198=GO_REF:0000029, GO:0007010=PMID:1282112, GO:0045111=GO_REF:0000052, GO:0045095=GO_REF:0000002} Q01546 Keratin, type II cytoskeletal 2 oral protein 20111111 {GO:0005882=NAS, GO:0005198=NAS, GO:0007010=NAS, GO:0045111=IDA, GO:0045095=IEA} cytoskeleton organization intermediate filament, intermediate filament cytoskeleton, keratin filament structural molecule activity Human KRT77 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005198=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0045095=GO_REF:0000002} Q7Z794 Keratin, type II cytoskeletal 1b protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0005198=IEA, GO:0005575=ND, GO:0045095=IEA} biological_process cellular_component, keratin filament molecular_function, structural molecule activity Human KRT78 InterPro UniProtKB {GO:0005198=GO_REF:0000002, GO:0045095=GO_REF:0000002} Q8N1N4 Keratin, type II cytoskeletal 78 protein 20130413 {GO:0005198=IEA, GO:0045095=IEA} keratin filament structural molecule activity Human InterPro:IPR003054 KRT79 InterPro UniProtKB {GO:0005198=GO_REF:0000002, GO:0045095=GO_REF:0000002} Q5XKE5 Keratin, type II cytoskeletal 79 protein 20130413 {GO:0005198=IEA, GO:0045095=IEA} keratin filament structural molecule activity Human InterPro:IPR003054 KRT8 BHF-UCL UniProtKB {GO:0005515=PMID:21988832, GO:0005882=PMID:10852826, GO:0005737=PMID:19188445, GO:0005198=GO_REF:0000029, GO:0019048=GO_REF:0000037, GO:0097110=PMID:10852826, GO:0007010=GO_REF:0000029, GO:0005654=GO_REF:0000039, GO:0045095=GO_REF:0000002, GO:0016363=GO_REF:0000039} P05787 Keratin, type II cytoskeletal 8 protein 20120928 {GO:0005515=IPI, GO:0005882=IDA, GO:0005737=IDA, GO:0005198=NAS, GO:0019048=IEA, GO:0097110=IPI, GO:0007010=NAS, GO:0005654=IEA, GO:0045095=IEA, GO:0016363=IEA} cytoskeleton organization, virus-host interaction cytoplasm, intermediate filament, keratin filament, nuclear matrix, nucleoplasm protein binding, scaffold protein binding, structural molecule activity Human KRT80 InterPro UniProtKB {GO:0005198=GO_REF:0000002, GO:0045095=GO_REF:0000002} Q6KB66 Keratin, type II cytoskeletal 80 protein 20130413 {GO:0005198=IEA, GO:0045095=IEA} keratin filament structural molecule activity Human InterPro:IPR003054 KRT81 IntAct UniProtKB {GO:0005515=PMID:23088713, GO:0005198=GO_REF:0000002, GO:0045095=GO_REF:0000002} Q14533 Keratin, type II cuticular Hb1 protein 20130415 {GO:0005515=IPI, GO:0005198=IEA, GO:0045095=IEA} keratin filament protein binding, structural molecule activity Human UniProtKB:P09022 KRT82 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0045095=PMID:10692104, GO:0030280=PMID:10692104} Q9NSB4 Keratin, type II cuticular Hb2 protein 20111214 {GO:0008150=ND, GO:0005575=ND, GO:0045095=IDA, GO:0030280=NAS} biological_process cellular_component, keratin filament structural constituent of epidermis Human KRT83 PINC UniProtKB {GO:0008544=PMID:9084137, GO:0005198=GO_REF:0000002, GO:0045095=GO_REF:0000002} P78385 Keratin, type II cuticular Hb3 protein 20030904 {GO:0008544=TAS, GO:0005198=IEA, GO:0045095=IEA} epidermis development keratin filament structural molecule activity Human KRT84 UniProtKB UniProtKB {GO:0045616=GO_REF:0000019, GO:0035878=PMID:10692104, GO:0005200=PMID:10692104, GO:0005575=GO_REF:0000015, GO:0045095=PMID:10692104, GO:0001942=PMID:10692104, GO:0030280=GO_REF:0000029} Q9NSB2 Keratin, type II cuticular Hb4 protein 20111214 {GO:0045616=IEA, GO:0035878=NAS, GO:0005200=NAS, GO:0005575=ND, GO:0045095=IDA, GO:0001942=NAS, GO:0030280=NAS} hair follicle development, nail development, regulation of keratinocyte differentiation cellular_component, keratin filament structural constituent of cytoskeleton, structural constituent of epidermis Human KRT85 PINC UniProtKB {GO:0008544=PMID:9084137, GO:0005198=GO_REF:0000002, GO:0045095=GO_REF:0000002} P78386 Keratin, type II cuticular Hb5 protein 20030904 {GO:0008544=TAS, GO:0005198=IEA, GO:0045095=IEA} epidermis development keratin filament structural molecule activity Human KRT86 UniProtKB UniProtKB {GO:0005882=GO_REF:0000029, GO:0005198=GO_REF:0000029, GO:0007010=GO_REF:0000029, GO:0045095=GO_REF:0000002} O43790 Keratin, type II cuticular Hb6 protein 20050308 {GO:0005882=NAS, GO:0005198=NAS, GO:0007010=NAS, GO:0045095=IEA} cytoskeleton organization intermediate filament, keratin filament structural molecule activity Human KRT9 PINC UniProtKB {GO:0005882=GO_REF:0000037, GO:0045109=PMID:10218578, GO:0008544=PMID:8647270, GO:0005198=GO_REF:0000002, GO:0005200=PMID:8647270, GO:0043588=PMID:7507869, GO:0007283=GO_REF:0000019} P35527 Keratin, type I cytoskeletal 9 protein 20030904 {GO:0005882=IEA, GO:0045109=IMP, GO:0008544=TAS, GO:0005198=IEA, GO:0005200=TAS, GO:0043588=IDA, GO:0007283=IEA} epidermis development, intermediate filament organization, skin development, spermatogenesis intermediate filament structural constituent of cytoskeleton, structural molecule activity Human KRTAP10-7 InterPro UniProtKB {GO:0045095=GO_REF:0000002} P60409 Keratin-associated protein 10-7 protein 20130413 {GO:0045095=IEA} keratin filament Human InterPro:IPR002494 KRTAP11-1 InterPro UniProtKB {GO:0005198=GO_REF:0000002, GO:0045095=GO_REF:0000002} Q8IUC1 Keratin-associated protein 11-1 protein 20130413 {GO:0005198=IEA, GO:0045095=IEA} keratin filament structural molecule activity Human InterPro:IPR007659 KRTAP19-5 UniProtKB UniProtKB {GO:0005882=GO_REF:0000037} Q3LI72 Keratin-associated protein 19-5 protein 20130413 {GO:0005882=IEA} intermediate filament Human UniProtKB-KW:KW-0416 KRTAP26-1 UniProtKB UniProtKB {GO:0005882=GO_REF:0000037} Q6PEX3 Keratin-associated protein 26-1 protein 20130413 {GO:0005882=IEA} intermediate filament Human UniProtKB-KW:KW-0416 KRTAP3-2 InterPro UniProtKB {GO:0005198=GO_REF:0000002, GO:0045095=GO_REF:0000002} Q9BYR7 Keratin-associated protein 3-2 protein 20130413 {GO:0005198=IEA, GO:0045095=IEA} keratin filament structural molecule activity Human InterPro:IPR007659 KRTAP3-3 InterPro UniProtKB {GO:0005198=GO_REF:0000002, GO:0045095=GO_REF:0000002} Q9BYR6 Keratin-associated protein 3-3 protein 20130413 {GO:0005198=IEA, GO:0045095=IEA} keratin filament structural molecule activity Human InterPro:IPR007659 KRTAP4-12 InterPro UniProtKB {GO:0045095=GO_REF:0000002} Q9BQ66 Keratin-associated protein 4-12 protein 20130413 {GO:0045095=IEA} keratin filament Human InterPro:IPR002494 KRTAP5-9 PINC UniProtKB {GO:0008544=PMID:1703541, GO:0045095=GO_REF:0000002} P26371 Keratin-associated protein 5-9 protein 20030904 {GO:0008544=TAS, GO:0045095=IEA} epidermis development keratin filament Human KRTAP9-2 InterPro UniProtKB {GO:0045095=GO_REF:0000002} Q9BYQ4 Keratin-associated protein 9-2 protein 20130413 {GO:0045095=IEA} keratin filament Human InterPro:IPR002494 KRTAP9-3 InterPro UniProtKB {GO:0045095=GO_REF:0000002} Q9BYQ3 Keratin-associated protein 9-3 protein 20130413 {GO:0045095=IEA} keratin filament Human InterPro:IPR002494 KRTCAP2 HGNC UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037, GO:0008250=GO_REF:0000024} Q8N6L1 Keratinocyte-associated protein 2 protein 20070103 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND, GO:0016021=IEA, GO:0008250=ISS} biological_process cellular_component, integral to membrane, oligosaccharyltransferase complex molecular_function colocalizes_with Human UniProtKB:Q5RL79 KRTCAP3 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q53RY4 Keratinocyte-associated protein 3 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 KSR1 UniProtKB UniProtKB {GO:0005622=GO_REF:0000029, GO:0035556=GO_REF:0000002, GO:0004672=PMID:8521512, GO:0004674=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0006468=GO_REF:0000029, GO:0007265=PMID:8521512, GO:0043410=GO_REF:0000019, GO:0005524=GO_REF:0000029, GO:0005078=GO_REF:0000019, GO:0046872=GO_REF:0000037} Q8IVT5 Kinase suppressor of Ras 1 protein 20050308 {GO:0005622=NAS, GO:0035556=IEA, GO:0004672=NAS, GO:0004674=IEA, GO:0005789=IEA, GO:0006468=NAS, GO:0007265=NAS, GO:0043410=IEA, GO:0005524=NAS, GO:0005078=IEA, GO:0046872=IEA} Ras protein signal transduction, intracellular signal transduction, positive regulation of MAPK cascade, protein phosphorylation endoplasmic reticulum membrane, intracellular ATP binding, MAP-kinase scaffold activity, metal ion binding, protein kinase activity, protein serine/threonine kinase activity Human KSR2 ENSEMBL UniProtKB {GO:0035556=GO_REF:0000002, GO:0004672=GO_REF:0000002, GO:0019722=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0004674=GO_REF:0000002, GO:0031434=GO_REF:0000019, GO:0043410=GO_REF:0000019, GO:0005524=GO_REF:0000002, GO:0005078=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=GO_REF:0000019} Q6VAB6 Kinase suppressor of Ras 2 protein 20130413 {GO:0035556=IEA, GO:0004672=IEA, GO:0019722=IEA, GO:0005886=IEA, GO:0004674=IEA, GO:0031434=IEA, GO:0043410=IEA, GO:0005524=IEA, GO:0005078=IEA, GO:0046872=IEA, GO:0005829=IEA} calcium-mediated signaling, intracellular signal transduction, positive regulation of MAPK cascade cytosol, plasma membrane ATP binding, MAP-kinase scaffold activity, metal ion binding, mitogen-activated protein kinase kinase binding, protein kinase activity, protein serine/threonine kinase activity Human Ensembl:ENSMUSP00000137670 KTI12 UniProtKB UniProtKB {GO:0005524=GO_REF:0000037} Q96EK9 Protein KTI12 homolog protein 20130413 {GO:0005524=IEA} ATP binding Human UniProtKB-KW:KW-0067 KTN1 HPA UniProtKB {GO:0003674=GO_REF:0000015, GO:0016020=PMID:7787243, GO:0005887=PMID:7787243, GO:0005783=GO_REF:0000052, GO:0005789=GO_REF:0000039, GO:0030176=GO_REF:0000002, GO:0016021=PMID:7787244, GO:0019894=GO_REF:0000002, GO:0015031=GO_REF:0000002, GO:0007018=GO_REF:0000002} Q86UP2 Kinectin protein 20080205 {GO:0003674=ND, GO:0016020=TAS, GO:0005887=TAS, GO:0005783=IDA, GO:0005789=IEA, GO:0030176=IEA, GO:0016021=TAS, GO:0019894=IEA, GO:0015031=IEA, GO:0007018=IEA} microtubule-based movement, protein transport endoplasmic reticulum, endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane, integral to membrane, integral to plasma membrane, membrane kinesin binding, molecular_function Human KXD1 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0031083=GO_REF:0000024, GO:0016192=GO_REF:0000024} Q9BQD3 KxDL motif-containing protein 1 protein 20130415 {GO:0005515=IPI, GO:0031083=ISS, GO:0016192=ISS} vesicle-mediated transport BLOC-1 complex protein binding Human UniProtKB:Q9UJ41 KY UniProtKB UniProtKB {GO:0030018=GO_REF:0000024, GO:0007528=GO_REF:0000019, GO:0006508=GO_REF:0000037, GO:0008233=GO_REF:0000037, GO:0005856=GO_REF:0000039} Q8NBH2 Kyphoscoliosis peptidase protein 20100804 {GO:0030018=ISS, GO:0007528=IEA, GO:0006508=IEA, GO:0008233=IEA, GO:0005856=IEA} neuromuscular junction development, proteolysis Z disc, cytoskeleton peptidase activity Human UniProtKB:Q8C8H8 KYNU HPA UniProtKB {GO:0006569=Reactome:REACT_916, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0030429=Reactome:REACT_2234, GO:0044281=Reactome:REACT_111217, GO:0034516=PMID:1939450, GO:0042803=PMID:11985583, GO:0043420=PMID:11985583, GO:0005829=Reactome:REACT_2234, GO:0005739=PMID:6468727, GO:0034641=Reactome:REACT_13, GO:0097053=GO_REF:0000041, GO:0005737=GO_REF:0000052, GO:0019805=PMID:9291104, GO:0019441=GO_REF:0000019, GO:0030170=GO_REF:0000019, GO:0019442=GO_REF:0000019, GO:0034341=PMID:9291104, GO:0009435=GO_REF:0000041} Q16719 Kynureninase protein 20101115 {GO:0006569=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0030429=TAS, GO:0044281=TAS, GO:0034516=IMP, GO:0042803=IDA, GO:0043420=IDA, GO:0005829=TAS, GO:0005739=IDA, GO:0034641=TAS, GO:0097053=IEA, GO:0005737=IDA, GO:0019805=IDA, GO:0019441=IEA, GO:0030170=IEA, GO:0019442=IEA, GO:0034341=IDA, GO:0009435=IEA} L-kynurenine catabolic process, NAD biosynthetic process, anthranilate metabolic process, cellular nitrogen compound metabolic process, quinolinate biosynthetic process, response to interferon-gamma, response to vitamin B6, small molecule metabolic process, tryptophan catabolic process, tryptophan catabolic process to acetyl-CoA, tryptophan catabolic process to kynurenine cytoplasm, cytosol, mitochondrion, nucleolus, nucleus kynureninase activity, protein homodimerization activity, pyridoxal phosphate binding Human L1CAM BHF-UCL UniProtKB {GO:0008219=GO_REF:0000037, GO:0022409=GO_REF:0000019, GO:0005886=Reactome:REACT_22408, GO:0033631=GO_REF:0000019, GO:0050900=Reactome:REACT_12051, GO:0043621=GO_REF:0000019, GO:0007399=PMID:1769655, GO:0050850=GO_REF:0000019, GO:0042802=GO_REF:0000019, GO:0042734=GO_REF:0000019, GO:0034109=GO_REF:0000019, GO:0005178=GO_REF:0000019, GO:0006935=PMID:19909241, GO:0007596=Reactome:REACT_604, GO:0007411=Reactome:REACT_18266, GO:0043195=GO_REF:0000019, GO:0007159=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0033691=GO_REF:0000019, GO:0007155=PMID:7920659, GO:0007156=GO_REF:0000019, GO:0007166=GO_REF:0000019, GO:0009897=GO_REF:0000019, GO:0007157=GO_REF:0000019} P32004 Neural cell adhesion molecule L1 protein 20110907 {GO:0008219=IEA, GO:0022409=IEA, GO:0005886=TAS, GO:0033631=IEA, GO:0050900=TAS, GO:0043621=IEA, GO:0007399=TAS, GO:0050850=IEA, GO:0042802=IEA, GO:0042734=IEA, GO:0034109=IEA, GO:0005178=IEA, GO:0006935=TAS, GO:0007596=TAS, GO:0007411=TAS, GO:0043195=IEA, GO:0007159=IEA, GO:0016021=IEA, GO:0033691=IEA, GO:0007155=NAS, GO:0007156=IEA, GO:0007166=IEA, GO:0009897=IEA, GO:0007157=IEA} axon guidance, blood coagulation, cell adhesion, cell death, cell surface receptor signaling pathway, cell-cell adhesion mediated by integrin, chemotaxis, heterophilic cell-cell adhesion, homophilic cell adhesion, homotypic cell-cell adhesion, leukocyte cell-cell adhesion, leukocyte migration, nervous system development, positive regulation of calcium-mediated signaling, positive regulation of cell-cell adhesion external side of plasma membrane, integral to membrane, plasma membrane, presynaptic membrane, terminal bouton identical protein binding, integrin binding, protein self-association, sialic acid binding Human L1TD1 null null {} null null null null {} null null null L2HGDH Reactome UniProtKB {GO:0005739=PMID:16005139, GO:0006103=Reactome:REACT_25367, GO:0005743=Reactome:REACT_24926, GO:0016491=GO_REF:0000002, GO:0031305=PMID:16005139, GO:0047545=PMID:16005139, GO:0044281=Reactome:REACT_111217, GO:0016021=PMID:16005139, GO:0044267=PMID:16005139} Q9H9P8 L-2-hydroxyglutarate dehydrogenase, mitochondrial protein 20130301 {GO:0005739=IDA, GO:0006103=TAS, GO:0005743=TAS, GO:0016491=IEA, GO:0031305=NAS, GO:0047545=IDA, GO:0044281=TAS, GO:0016021=IDA, GO:0044267=IDA} 2-oxoglutarate metabolic process, cellular protein metabolic process, small molecule metabolic process integral to membrane, integral to mitochondrial inner membrane, mitochondrial inner membrane, mitochondrion 2-hydroxyglutarate dehydrogenase activity, oxidoreductase activity Human L3MBTL1 IntAct UniProtKB {GO:0030097=PMID:15334543, GO:0005515=PMID:17540172, GO:0000793=PMID:10445843, GO:0007088=PMID:10445843, GO:0003700=GO_REF:0000002, GO:0005730=PMID:10445843, GO:0031491=PMID:17540172, GO:0005634=PMID:18408754, GO:0031493=PMID:17540172, GO:0035064=PMID:22120668, GO:0032093=PMID:12588862, GO:0006351=GO_REF:0000037, GO:0042802=PMID:12588862, GO:0045652=PMID:18474616, GO:0042393=PMID:18474616, GO:0003682=PMID:18408754, GO:0051726=PMID:15566354, GO:0008270=GO_REF:0000002, GO:0005654=PMID:10445843, GO:0045892=PMID:12588862, GO:0000785=PMID:18408754, GO:0016568=PMID:17540172} Q9Y468 Lethal(3)malignant brain tumor-like protein 1 protein 20130415 {GO:0030097=IEP, GO:0005515=IPI, GO:0000793=IDA, GO:0007088=IMP, GO:0003700=IEA, GO:0005730=IDA, GO:0031491=IDA, GO:0005634=IDA, GO:0031493=IDA, GO:0035064=IDA, GO:0032093=IPI, GO:0006351=IEA, GO:0042802=IPI, GO:0045652=IDA, GO:0042393=IPI, GO:0003682=IDA, GO:0051726=NAS, GO:0008270=IEA, GO:0005654=IDA, GO:0045892=IMP, GO:0000785=IDA, GO:0016568=IDA} chromatin modification, hemopoiesis, negative regulation of transcription, DNA-dependent, regulation of cell cycle, regulation of megakaryocyte differentiation, regulation of mitosis, transcription, DNA-dependent chromatin, condensed chromosome, nucleolus, nucleoplasm, nucleus SAM domain binding, chromatin binding, histone binding, identical protein binding, methylated histone residue binding, nucleosomal histone binding, nucleosome binding, protein binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB:P62805 L3MBTL2 LIFEdb UniProtKB {GO:0042393=PMID:17540172, GO:0006355=GO_REF:0000037, GO:0003714=GO_REF:0000029, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000054, GO:0035064=PMID:19233876, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000029} Q969R5 Lethal(3)malignant brain tumor-like protein 2 protein 20100607 {GO:0042393=IPI, GO:0006355=IEA, GO:0003714=NAS, GO:0008270=IEA, GO:0005634=IDA, GO:0035064=IDA, GO:0006351=IEA, GO:0016568=NAS} chromatin modification, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus histone binding, methylated histone residue binding, transcription corepressor activity, zinc ion binding Human L3MBTL3 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000029, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q96JM7 Lethal(3)malignant brain tumor-like protein 3 protein 20061026 {GO:0003674=ND, GO:0006355=IEA, GO:0005634=NAS, GO:0006351=IEA, GO:0016568=IEA} chromatin modification, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus molecular_function Human L3MBTL4 UniProtKB UniProtKB {GO:0006355=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q8NA19 Lethal(3)malignant brain tumor-like protein 4 protein 20130413 {GO:0006355=IEA, GO:0003700=IEA, GO:0008270=IEA, GO:0005634=IEA, GO:0006351=IEA, GO:0016568=IEA} chromatin modification, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB-SubCell:SL-0191 LACRT UniProtKB UniProtKB {GO:0050679=PMID:16923831, GO:0070075=PMID:18840430, GO:0008284=PMID:16982797, GO:0019722=PMID:11419941, GO:0051047=PMID:11419941, GO:0005518=PMID:11419941, GO:0033173=PMID:16923831, GO:0050731=PMID:11419941, GO:0051533=PMID:16923831, GO:0005576=PMID:17850790, GO:0001948=PMID:11419941, GO:0047485=PMID:16982797, GO:0043237=PMID:11419941, GO:0034067=PMID:16923831, GO:0001968=PMID:11419941, GO:0030141=PMID:11419941, GO:0051281=PMID:16923831, GO:0008083=PMID:16982797} Q9GZZ8 Extracellular glycoprotein lacritin protein 20081013 {GO:0050679=IDA, GO:0070075=NAS, GO:0008284=IDA, GO:0019722=IDA, GO:0051047=IDA, GO:0005518=IDA, GO:0033173=IDA, GO:0050731=IDA, GO:0051533=IDA, GO:0005576=IDA, GO:0001948=IDA, GO:0047485=IPI, GO:0043237=IDA, GO:0034067=IDA, GO:0001968=IDA, GO:0030141=IDA, GO:0051281=IDA, GO:0008083=IDA} calcineurin-NFAT signaling cascade, calcium-mediated signaling, positive regulation of NFAT protein import into nucleus, positive regulation of cell proliferation, positive regulation of epithelial cell proliferation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of release of sequestered calcium ion into cytosol, positive regulation of secretion, protein localization to Golgi apparatus, tear secretion extracellular region, secretory granule collagen binding, fibronectin binding, glycoprotein binding, growth factor activity, laminin-1 binding, protein N-terminus binding Human LACTB HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0016787=GO_REF:0000037} P83111 Serine beta-lactamase-like protein LACTB, mitochondrial protein 20111111 {GO:0005739=IDA, GO:0005737=IDA, GO:0016787=IEA} cytoplasm, mitochondrion hydrolase activity Human LACTB2 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0016787=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q53H82 Beta-lactamase-like protein 2 protein 20130413 {GO:0005739=IEA, GO:0016787=IEA, GO:0046872=IEA} mitochondrion hydrolase activity, metal ion binding Human Ensembl:ENSMUSP00000027071 LAD1 HPA UniProtKB {GO:0005198=PMID:9119369, GO:0015629=GO_REF:0000052, GO:0005604=GO_REF:0000039} O00515 Ladinin-1 protein 20111111 {GO:0005198=TAS, GO:0015629=IDA, GO:0005604=IEA} actin cytoskeleton, basement membrane structural molecule activity Human LAG3 MGI UniProtKB {GO:0045085=GO_REF:0000019, GO:0042289=PMID:9159144, GO:0050868=GO_REF:0000019, GO:0045954=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0003823=PMID:1692078, GO:0009897=GO_REF:0000019, GO:0007166=GO_REF:0000019, GO:0004888=GO_REF:0000019} P18627 Lymphocyte activation gene 3 protein protein 20101104 {GO:0045085=IEA, GO:0042289=IDA, GO:0050868=IEA, GO:0045954=IEA, GO:0016021=IEA, GO:0003823=TAS, GO:0009897=IEA, GO:0007166=IEA, GO:0004888=IEA} cell surface receptor signaling pathway, negative regulation of T cell activation, negative regulation of interleukin-2 biosynthetic process, positive regulation of natural killer cell mediated cytotoxicity external side of plasma membrane, integral to membrane MHC class II protein binding, antigen binding, transmembrane signaling receptor activity Human LAGE3 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q14657 L antigen family member 3 protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human LAIR1 HPA UniProtKB {GO:0005515=PMID:16754721, GO:0005886=GO_REF:0000052, GO:0016021=GO_REF:0000037} Q6GTX8 Leukocyte-associated immunoglobulin-like receptor 1 protein 20100326 {GO:0005515=IPI, GO:0005886=IDA, GO:0016021=IEA} integral to membrane, plasma membrane protein binding Human LALBA PINC UniProtKB {GO:0005989=GO_REF:0000037, GO:0007165=PMID:7644538, GO:0005509=GO_REF:0000002, GO:0007267=PMID:7644538, GO:0004461=GO_REF:0000002, GO:0006917=PMID:7644538, GO:0005615=PMID:7644538, GO:0042742=PMID:7644538} P00709 Alpha-lactalbumin protein 20030904 {GO:0005989=IEA, GO:0007165=TAS, GO:0005509=IEA, GO:0007267=TAS, GO:0004461=IEA, GO:0006917=TAS, GO:0005615=TAS, GO:0042742=TAS} cell-cell signaling, defense response to bacterium, induction of apoptosis, lactose biosynthetic process, signal transduction extracellular space calcium ion binding, lactose synthase activity Human LAMA1 Reactome UniProtKB {GO:0030334=GO_REF:0000002, GO:0002011=GO_REF:0000019, GO:0005578=GO_REF:0000024, GO:0005102=GO_REF:0000002, GO:0005606=PMID:10964500, GO:0005576=Reactome:REACT_13613, GO:0005608=PMID:10964500, GO:0005615=PMID:10964500, GO:0030155=GO_REF:0000002, GO:0045198=GO_REF:0000019, GO:0005604=PMID:2099832, GO:0045995=GO_REF:0000002, GO:0060441=GO_REF:0000019, GO:0061304=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0005911=GO_REF:0000019, GO:0043208=GO_REF:0000019, GO:0007155=GO_REF:0000037, GO:0007166=GO_REF:0000024, GO:0005201=GO_REF:0000024, GO:0060445=GO_REF:0000019} P25391 Laminin subunit alpha-1 protein 20080310 {GO:0030334=IEA, GO:0002011=IEA, GO:0005578=ISS, GO:0005102=IEA, GO:0005606=IPI, GO:0005576=TAS, GO:0005608=IPI, GO:0005615=IDA, GO:0030155=IEA, GO:0045198=IEA, GO:0005604=IDA, GO:0045995=IEA, GO:0060441=IEA, GO:0061304=IEA, GO:0007411=TAS, GO:0005911=IEA, GO:0043208=IEA, GO:0007155=IEA, GO:0007166=ISS, GO:0005201=ISS, GO:0060445=IEA} axon guidance, branching involved in salivary gland morphogenesis, cell adhesion, cell surface receptor signaling pathway, epithelial tube branching involved in lung morphogenesis, establishment of epithelial cell apical/basal polarity, morphogenesis of an epithelial sheet, regulation of cell adhesion, regulation of cell migration, regulation of embryonic development, retinal blood vessel morphogenesis basement membrane, cell-cell junction, extracellular region, extracellular space, laminin-1 complex, laminin-3 complex, proteinaceous extracellular matrix extracellular matrix structural constituent, glycosphingolipid binding, receptor binding Human LAMA2 BHF-UCL UniProtKB {GO:0030334=GO_REF:0000002, GO:0005102=GO_REF:0000002, GO:0005606=GO_REF:0000002, GO:0005576=Reactome:REACT_13716, GO:0030155=GO_REF:0000002, GO:0005604=PMID:14557481, GO:0031012=PMID:22261194, GO:0045995=GO_REF:0000002, GO:0042383=GO_REF:0000019, GO:0032224=GO_REF:0000019, GO:0007517=PMID:7550355, GO:0007411=GO_REF:0000019, GO:0005198=PMID:2185464, GO:0007155=GO_REF:0000037} P24043 Laminin subunit alpha-2 protein 20120228 {GO:0030334=IEA, GO:0005102=IEA, GO:0005606=IEA, GO:0005576=TAS, GO:0030155=IEA, GO:0005604=IDA, GO:0031012=ISS, GO:0045995=IEA, GO:0042383=IEA, GO:0032224=IEA, GO:0007517=TAS, GO:0007411=IEA, GO:0005198=TAS, GO:0007155=IEA} axon guidance, cell adhesion, muscle organ development, positive regulation of synaptic transmission, cholinergic, regulation of cell adhesion, regulation of cell migration, regulation of embryonic development basement membrane, extracellular matrix, extracellular region, laminin-1 complex, sarcolemma receptor binding, structural molecule activity colocalizes_with Human UniProtKB:F1S2Z4 LAMA3 InterPro UniProtKB {GO:0030334=GO_REF:0000002, GO:0034329=Reactome:REACT_20676, GO:0005102=GO_REF:0000002, GO:0005606=GO_REF:0000002, GO:0005576=Reactome:REACT_150470, GO:0030155=GO_REF:0000002, GO:0005604=PMID:8586427, GO:0045995=GO_REF:0000002, GO:0005610=GO_REF:0000019, GO:0008544=PMID:8586427, GO:0005198=PMID:8586427, GO:0030198=Reactome:REACT_118779, GO:0031581=Reactome:REACT_20537, GO:0007155=GO_REF:0000002} Q6VU69 Laminin alpha 3 splice variant a protein 20130413 {GO:0030334=IEA, GO:0034329=TAS, GO:0005102=IEA, GO:0005606=IEA, GO:0005576=TAS, GO:0030155=IEA, GO:0005604=TAS, GO:0045995=IEA, GO:0005610=IEA, GO:0008544=TAS, GO:0005198=NAS, GO:0030198=TAS, GO:0031581=TAS, GO:0007155=IEA} cell adhesion, cell junction assembly, epidermis development, extracellular matrix organization, hemidesmosome assembly, regulation of cell adhesion, regulation of cell migration, regulation of embryonic development basement membrane, extracellular region, laminin-1 complex, laminin-5 complex receptor binding, structural molecule activity Human InterPro:IPR009254 LAMA4 BHF-UCL UniProtKB {GO:0031012=PMID:22261194, GO:0045995=GO_REF:0000002, GO:0030334=GO_REF:0000002, GO:0001568=GO_REF:0000019, GO:0050873=GO_REF:0000019, GO:0005102=GO_REF:0000002, GO:0005605=PMID:7959779, GO:0005606=GO_REF:0000002, GO:0007155=GO_REF:0000037, GO:0030155=GO_REF:0000002, GO:0005201=PMID:7959779, GO:0005604=PMID:14557481} Q16363 Laminin subunit alpha-4 protein 20120228 {GO:0031012=ISS, GO:0045995=IEA, GO:0030334=IEA, GO:0001568=IEA, GO:0050873=IEA, GO:0005102=IEA, GO:0005605=TAS, GO:0005606=IEA, GO:0007155=IEA, GO:0030155=IEA, GO:0005201=TAS, GO:0005604=IDA} blood vessel development, brown fat cell differentiation, cell adhesion, regulation of cell adhesion, regulation of cell migration, regulation of embryonic development basal lamina, basement membrane, extracellular matrix, laminin-1 complex extracellular matrix structural constituent, receptor binding colocalizes_with Human UniProtKB:F1RZM4 LAMA5 BHF-UCL UniProtKB {GO:0001658=GO_REF:0000019, GO:0008037=PMID:11821406, GO:0030324=GO_REF:0000019, GO:0008283=PMID:11821406, GO:0001755=GO_REF:0000019, GO:0009790=PMID:11821406, GO:0005615=PMID:10964500, GO:0030155=GO_REF:0000002, GO:0001738=GO_REF:0000019, GO:0030154=PMID:11821406, GO:0042127=GO_REF:0000019, GO:0048041=PMID:11821406, GO:0007010=PMID:11821406, GO:0034446=PMID:16236823, GO:0042475=GO_REF:0000019, GO:0045446=PMID:11821406, GO:0001942=GO_REF:0000019, GO:0030334=GO_REF:0000002, GO:0005605=PMID:11821406, GO:0005606=GO_REF:0000002, GO:0001525=PMID:11821406, GO:0043260=PMID:16236823, GO:0005604=PMID:14557481, GO:0045995=GO_REF:0000002, GO:0042384=GO_REF:0000019, GO:0043259=PMID:16236823, GO:0005178=PMID:11821406, GO:0007517=GO_REF:0000019, GO:0016331=GO_REF:0000019, GO:0016477=PMID:11821406, GO:0007229=PMID:11821406, GO:0005198=PMID:11821406, GO:0090002=GO_REF:0000019, GO:0060445=GO_REF:0000019} O15230 Laminin subunit alpha-5 protein 20090408 {GO:0001658=IEA, GO:0008037=NAS, GO:0030324=IEA, GO:0008283=NAS, GO:0001755=IEA, GO:0009790=NAS, GO:0005615=IDA, GO:0030155=IEA, GO:0001738=IEA, GO:0030154=NAS, GO:0042127=IEA, GO:0048041=NAS, GO:0007010=NAS, GO:0034446=IDA, GO:0042475=IEA, GO:0045446=NAS, GO:0001942=IEA, GO:0030334=IEA, GO:0005605=NAS, GO:0005606=IEA, GO:0001525=NAS, GO:0043260=TAS, GO:0005604=IDA, GO:0045995=IEA, GO:0042384=IEA, GO:0043259=TAS, GO:0005178=IDA, GO:0007517=IEA, GO:0016331=IEA, GO:0016477=IDA, GO:0007229=IMP, GO:0005198=IC, GO:0090002=IEA, GO:0060445=IEA} angiogenesis, branching involved in salivary gland morphogenesis, branching involved in ureteric bud morphogenesis, cell differentiation, cell migration, cell proliferation, cell recognition, cilium assembly, cytoskeleton organization, embryo development, endothelial cell differentiation, establishment of protein localization to plasma membrane, focal adhesion assembly, hair follicle development, integrin-mediated signaling pathway, lung development, morphogenesis of a polarized epithelium, morphogenesis of embryonic epithelium, muscle organ development, neural crest cell migration, odontogenesis of dentin-containing tooth, regulation of cell adhesion, regulation of cell migration, regulation of cell proliferation, regulation of embryonic development, substrate adhesion-dependent cell spreading basal lamina, basement membrane, extracellular space, laminin-1 complex, laminin-10 complex, laminin-11 complex integrin binding, structural molecule activity Human LAMB1 BHF-UCL UniProtKB {GO:0050679=PMID:14557481, GO:0048471=GO_REF:0000024, GO:0030335=PMID:16289578, GO:0007566=GO_REF:0000019, GO:0005606=PMID:14557481, GO:0005576=Reactome:REACT_13716, GO:0005607=PMID:16289578, GO:0005615=PMID:10964500, GO:0031175=PMID:15894315, GO:0005604=PMID:2099832, GO:0031012=PMID:22261194, GO:0007162=GO_REF:0000019, GO:0043259=PMID:10964500, GO:0005178=GO_REF:0000019, GO:0016477=GO_REF:0000019, GO:0043257=PMID:16289578, GO:0007411=Reactome:REACT_18266, GO:0005198=PMID:10842354, GO:0043208=GO_REF:0000019, GO:0042476=PMID:15894315, GO:0034446=PMID:16236823, GO:0007155=PMID:14557481, GO:0019899=GO_REF:0000019, GO:0005201=PMID:16289578} P07942 Laminin subunit beta-1 protein 20120228 {GO:0050679=TAS, GO:0048471=ISS, GO:0030335=IDA, GO:0007566=IEA, GO:0005606=TAS, GO:0005576=TAS, GO:0005607=IDA, GO:0005615=IDA, GO:0031175=IDA, GO:0005604=IDA, GO:0031012=ISS, GO:0007162=IEA, GO:0043259=IDA, GO:0005178=IEA, GO:0016477=IEA, GO:0043257=IDA, GO:0007411=TAS, GO:0005198=NAS, GO:0043208=IEA, GO:0042476=IDA, GO:0034446=IDA, GO:0007155=TAS, GO:0019899=IEA, GO:0005201=IDA} axon guidance, cell adhesion, cell migration, embryo implantation, negative regulation of cell adhesion, neuron projection development, odontogenesis, positive regulation of cell migration, positive regulation of epithelial cell proliferation, substrate adhesion-dependent cell spreading basement membrane, extracellular matrix, extracellular region, extracellular space, laminin-1 complex, laminin-10 complex, laminin-2 complex, laminin-8 complex, perinuclear region of cytoplasm enzyme binding, extracellular matrix structural constituent, glycosphingolipid binding, integrin binding, structural molecule activity colocalizes_with Human UniProtKB:Q95LE2 LAMB2 BHF-UCL UniProtKB {GO:0060041=GO_REF:0000019, GO:0072249=GO_REF:0000019, GO:0005605=PMID:7698745, GO:0014044=GO_REF:0000019, GO:0045202=GO_REF:0000019, GO:0005608=PMID:10964500, GO:0048677=GO_REF:0000019, GO:0043260=PMID:16236823, GO:0005604=PMID:14557481, GO:0031012=PMID:22261194, GO:0005178=GO_REF:0000019, GO:0072274=GO_REF:0000019, GO:0005198=PMID:7698745, GO:0007528=GO_REF:0000019, GO:0014002=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0007155=GO_REF:0000037, GO:0007601=GO_REF:0000019} P55268 Laminin subunit beta-2 protein 20120228 {GO:0060041=IEA, GO:0072249=IEA, GO:0005605=TAS, GO:0014044=IEA, GO:0045202=IEA, GO:0005608=IPI, GO:0048677=IEA, GO:0043260=TAS, GO:0005604=IDA, GO:0031012=ISS, GO:0005178=IEA, GO:0072274=IEA, GO:0005198=NAS, GO:0007528=IEA, GO:0014002=IEA, GO:0007411=IEA, GO:0007155=IEA, GO:0007601=IEA} Schwann cell development, astrocyte development, axon extension involved in regeneration, axon guidance, cell adhesion, metanephric glomerular basement membrane development, metanephric glomerular visceral epithelial cell development, neuromuscular junction development, retina development in camera-type eye, visual perception basal lamina, basement membrane, extracellular matrix, laminin-11 complex, laminin-3 complex, synapse integrin binding, structural molecule activity colocalizes_with Human UniProtKB:Q95J99 LAMB3 ENSEMBL UniProtKB {GO:0005515=PMID:19275936, GO:0005610=GO_REF:0000019, GO:0008544=PMID:7774918, GO:0030198=Reactome:REACT_118779, GO:0005198=PMID:7550320, GO:0050873=GO_REF:0000019, GO:0034329=Reactome:REACT_20676, GO:0031581=Reactome:REACT_20537, GO:0005576=Reactome:REACT_150470, GO:0007155=GO_REF:0000037} Q5THA1 Laminin subunit beta-3 protein 20130413 {GO:0005515=IPI, GO:0005610=IEA, GO:0008544=TAS, GO:0030198=TAS, GO:0005198=NAS, GO:0050873=IEA, GO:0034329=TAS, GO:0031581=TAS, GO:0005576=TAS, GO:0007155=IEA} brown fat cell differentiation, cell adhesion, cell junction assembly, epidermis development, extracellular matrix organization, hemidesmosome assembly extracellular region, laminin-5 complex protein binding, structural molecule activity Human Ensembl:ENSMUSP00000016315 LAMB4 UniProtKB UniProtKB {GO:0007155=GO_REF:0000037, GO:0005604=GO_REF:0000039} A4D0S4 Laminin subunit beta-4 protein 20130413 {GO:0007155=IEA, GO:0005604=IEA} cell adhesion basement membrane Human UniProtKB-SubCell:SL-0025 LAMC1 BHF-UCL UniProtKB {GO:0050679=PMID:14557481, GO:0005606=PMID:14557481, GO:0005576=Reactome:REACT_13716, GO:0043260=PMID:16236823, GO:0005615=PMID:10964500, GO:0005604=PMID:15159456, GO:0031012=PMID:22261194, GO:0043259=PMID:16236823, GO:0006461=PMID:15159456, GO:0007492=PMID:9885251, GO:0016477=PMID:15561105, GO:0022617=PMID:15159456, GO:0007411=Reactome:REACT_18266, GO:0043208=GO_REF:0000019, GO:0031581=PMID:15159456, GO:0034446=PMID:16236823, GO:0007155=PMID:15159456, GO:0005201=PMID:15159456} P11047 Laminin subunit gamma-1 protein 20120228 {GO:0050679=TAS, GO:0005606=TAS, GO:0005576=TAS, GO:0043260=TAS, GO:0005615=NAS, GO:0005604=IDA, GO:0031012=ISS, GO:0043259=TAS, GO:0006461=IDA, GO:0007492=TAS, GO:0016477=IMP, GO:0022617=IMP, GO:0007411=TAS, GO:0043208=IEA, GO:0031581=IMP, GO:0034446=IDA, GO:0007155=IDA, GO:0005201=IMP} axon guidance, cell adhesion, cell migration, endoderm development, extracellular matrix disassembly, hemidesmosome assembly, positive regulation of epithelial cell proliferation, protein complex assembly, substrate adhesion-dependent cell spreading basement membrane, extracellular matrix, extracellular region, extracellular space, laminin-1 complex, laminin-10 complex, laminin-11 complex extracellular matrix structural constituent, glycosphingolipid binding colocalizes_with Human UniProtKB:Q95J98 LAMC2 Reactome UniProtKB {GO:0005610=GO_REF:0000019, GO:0008544=PMID:8012394, GO:0030198=Reactome:REACT_118779, GO:0034329=Reactome:REACT_20676, GO:0031581=Reactome:REACT_20537, GO:0005576=Reactome:REACT_150470, GO:0007155=GO_REF:0000037, GO:0008201=GO_REF:0000019} Q13753 Laminin subunit gamma-2 protein 20130213 {GO:0005610=IEA, GO:0008544=TAS, GO:0030198=TAS, GO:0034329=TAS, GO:0031581=TAS, GO:0005576=TAS, GO:0007155=IEA, GO:0008201=IEA} cell adhesion, cell junction assembly, epidermis development, extracellular matrix organization, hemidesmosome assembly extracellular region, laminin-5 complex heparin binding Human LAMC3 PINC UniProtKB {GO:0000904=GO_REF:0000019, GO:0016020=PMID:10225960, GO:0060041=GO_REF:0000019, GO:0005198=PMID:10225960, GO:0014002=GO_REF:0000019, GO:0005578=PMID:10225960, GO:0007155=GO_REF:0000037, GO:0007601=GO_REF:0000019, GO:0005604=GO_REF:0000039} Q9Y6N6 Laminin subunit gamma-3 protein 20030904 {GO:0000904=IEA, GO:0016020=TAS, GO:0060041=IEA, GO:0005198=TAS, GO:0014002=IEA, GO:0005578=TAS, GO:0007155=IEA, GO:0007601=IEA, GO:0005604=IEA} astrocyte development, cell adhesion, cell morphogenesis involved in differentiation, retina development in camera-type eye, visual perception basement membrane, membrane, proteinaceous extracellular matrix structural molecule activity Human LAMP1 MGI UniProtKB {GO:0042470=GO_REF:0000019, GO:0048102=GO_REF:0000019, GO:0097208=GO_REF:0000019, GO:0005770=PMID:18388320, GO:0005771=GO_REF:0000019, GO:0006914=GO_REF:0000019, GO:0005765=GO_REF:0000039, GO:0005764=PMID:22792322, GO:0030425=GO_REF:0000019, GO:0042383=GO_REF:0000019, GO:0016020=PMID:3174652, GO:0005887=PMID:3174652, GO:0043025=GO_REF:0000019, GO:0009897=GO_REF:0000019, GO:0010008=GO_REF:0000039} P11279 Lysosome-associated membrane glycoprotein 1 protein 20120905 {GO:0042470=IEA, GO:0048102=IEA, GO:0097208=IEA, GO:0005770=IDA, GO:0005771=IEA, GO:0006914=IEA, GO:0005765=IEA, GO:0005764=IDA, GO:0030425=IEA, GO:0042383=IEA, GO:0016020=TAS, GO:0005887=TAS, GO:0043025=IEA, GO:0009897=IEA, GO:0010008=IEA} autophagic cell death, autophagy alveolar lamellar body, dendrite, endosome membrane, external side of plasma membrane, integral to plasma membrane, late endosome, lysosomal membrane, lysosome, melanosome, membrane, multivesicular body, neuronal cell body, sarcolemma Human LAMP2 Reactome UniProtKB {GO:0031088=Reactome:REACT_21266, GO:0005886=Reactome:REACT_21266, GO:0016020=PMID:15297306, GO:0007596=Reactome:REACT_604, GO:0005770=PMID:15229288, GO:0002576=Reactome:REACT_318, GO:0031902=PMID:21896273, GO:0030670=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0016021=GO_REF:0000037, GO:0005765=PMID:21896273, GO:0005764=PMID:19535332} P13473 Lysosome-associated membrane glycoprotein 2 protein 20130213 {GO:0031088=TAS, GO:0005886=TAS, GO:0016020=IDA, GO:0007596=TAS, GO:0005770=IDA, GO:0002576=TAS, GO:0031902=IDA, GO:0030670=IEA, GO:0030168=TAS, GO:0016021=IEA, GO:0005765=IDA, GO:0005764=IDA} blood coagulation, platelet activation, platelet degranulation integral to membrane, late endosome, late endosome membrane, lysosomal membrane, lysosome, membrane, phagocytic vesicle membrane, plasma membrane, platelet dense granule membrane Human LAMP3 PINC UniProtKB {GO:0097233=GO_REF:0000019, GO:0008283=PMID:9721848, GO:0016021=GO_REF:0000037, GO:0005765=GO_REF:0000039} Q9UQV4 Lysosome-associated membrane glycoprotein 3 protein 20061106 {GO:0097233=IEA, GO:0008283=TAS, GO:0016021=IEA, GO:0005765=IEA} cell proliferation alveolar lamellar body membrane, integral to membrane, lysosomal membrane Human LAMTOR1 HPA UniProtKB {GO:0005515=PMID:20381137, GO:0032418=GO_REF:0000024, GO:0032008=PMID:20381137, GO:0005886=GO_REF:0000052, GO:0032439=GO_REF:0000024, GO:0010872=PMID:20544018, GO:0005765=GO_REF:0000039, GO:0005764=PMID:20544018, GO:0043231=GO_REF:0000052, GO:0010874=PMID:20544018, GO:0005085=PMID:22980980, GO:0071986=PMID:20381137, GO:0071230=PMID:20381137, GO:0007032=GO_REF:0000024, GO:0060620=PMID:20544018, GO:0042632=PMID:20544018, GO:0005794=GO_REF:0000052, GO:0032947=PMID:22980980, GO:0001919=GO_REF:0000024, GO:0031902=GO_REF:0000024, GO:0016049=PMID:20381137, GO:0045121=GO_REF:0000024, GO:0034613=PMID:20381137, GO:0043410=GO_REF:0000024, GO:0007040=GO_REF:0000024} Q6IAA8 Ragulator complex protein LAMTOR1 protein 20080818 {GO:0005515=IPI, GO:0032418=ISS, GO:0032008=IMP, GO:0005886=IDA, GO:0032439=ISS, GO:0010872=IMP, GO:0005765=IEA, GO:0005764=IDA, GO:0043231=IDA, GO:0010874=IMP, GO:0005085=IDA, GO:0071986=IDA, GO:0071230=IMP, GO:0007032=ISS, GO:0060620=IMP, GO:0042632=IMP, GO:0005794=IDA, GO:0032947=IDA, GO:0001919=ISS, GO:0031902=ISS, GO:0016049=IMP, GO:0045121=ISS, GO:0034613=IMP, GO:0043410=ISS, GO:0007040=ISS} cell growth, cellular protein localization, cellular response to amino acid stimulus, cholesterol homeostasis, endosome localization, endosome organization, lysosome localization, lysosome organization, positive regulation of MAPK cascade, positive regulation of TOR signaling cascade, regulation of cholesterol efflux, regulation of cholesterol esterification, regulation of cholesterol import, regulation of receptor recycling Golgi apparatus, Ragulator complex, intracellular membrane-bounded organelle, late endosome membrane, lysosomal membrane, lysosome, membrane raft, plasma membrane guanyl-nucleotide exchange factor activity, protein binding, protein complex scaffold Human LAMTOR2 IntAct UniProtKB {GO:0005515=PMID:22980980, GO:0005085=PMID:22980980, GO:0032947=PMID:22980980, GO:0071986=PMID:20381137, GO:0000186=GO_REF:0000019, GO:0032008=PMID:20381137, GO:0071230=PMID:20381137, GO:0005770=GO_REF:0000024, GO:0016049=PMID:20381137, GO:0034613=PMID:20381137, GO:0005765=GO_REF:0000039} Q9Y2Q5 Ragulator complex protein LAMTOR2 protein 20130415 {GO:0005515=IPI, GO:0005085=IDA, GO:0032947=IDA, GO:0071986=IDA, GO:0000186=IEA, GO:0032008=IMP, GO:0071230=IMP, GO:0005770=ISS, GO:0016049=IMP, GO:0034613=IMP, GO:0005765=IEA} activation of MAPKK activity, cell growth, cellular protein localization, cellular response to amino acid stimulus, positive regulation of TOR signaling cascade Ragulator complex, late endosome, lysosomal membrane guanyl-nucleotide exchange factor activity, protein binding, protein complex scaffold Human UniProtKB:Q9UHA4 LAMTOR3 IntAct UniProtKB {GO:0005515=PMID:22980980, GO:0005085=PMID:22980980, GO:0032947=PMID:22980980, GO:0071986=PMID:20381137, GO:0032008=PMID:20381137, GO:0071230=PMID:20381137, GO:0034613=PMID:20381137} Q9UHA4 Ragulator complex protein LAMTOR3 protein 20130415 {GO:0005515=IPI, GO:0005085=IDA, GO:0032947=IDA, GO:0071986=IDA, GO:0032008=IMP, GO:0071230=IMP, GO:0034613=IMP} cellular protein localization, cellular response to amino acid stimulus, positive regulation of TOR signaling cascade Ragulator complex guanyl-nucleotide exchange factor activity, protein binding, protein complex scaffold Human UniProtKB:Q9Y2Q5 LANCL1 HPA UniProtKB {GO:0017124=PMID:19528316, GO:0043295=PMID:19528316, GO:0005737=GO_REF:0000039, GO:0007186=PMID:10944443, GO:0004930=PMID:9512664, GO:0005887=PMID:10944443, GO:0015630=GO_REF:0000052, GO:0008270=PMID:19528316, GO:0005634=GO_REF:0000039, GO:0003824=GO_REF:0000002, GO:0050750=PMID:15082773, GO:0043231=GO_REF:0000052} O43813 LanC-like protein 1 protein 20101115 {GO:0017124=IPI, GO:0043295=IDA, GO:0005737=IEA, GO:0007186=IDA, GO:0004930=TAS, GO:0005887=IDA, GO:0015630=IDA, GO:0008270=IDA, GO:0005634=IEA, GO:0003824=IEA, GO:0050750=IDA, GO:0043231=IDA} G-protein coupled receptor signaling pathway cytoplasm, integral to plasma membrane, intracellular membrane-bounded organelle, microtubule cytoskeleton, nucleus G-protein coupled receptor activity, SH3 domain binding, catalytic activity, glutathione binding, low-density lipoprotein particle receptor binding, zinc ion binding Human LANCL2 HPA UniProtKB {GO:0009789=PMID:19667068, GO:0005886=PMID:16979580, GO:0070273=PMID:16979580, GO:0005634=GO_REF:0000052, GO:0032266=PMID:16979580, GO:0003824=GO_REF:0000002, GO:0005525=PMID:11762191, GO:0005524=PMID:11762191, GO:0005829=PMID:12566319, GO:0005737=GO_REF:0000052, GO:0030864=PMID:16979580, GO:0045892=PMID:12566319, GO:0010314=PMID:16979580} Q9NS86 LanC-like protein 2 protein 20101115 {GO:0009789=IDA, GO:0005886=IDA, GO:0070273=IDA, GO:0005634=IDA, GO:0032266=IDA, GO:0003824=IEA, GO:0005525=NAS, GO:0005524=NAS, GO:0005829=IDA, GO:0005737=IDA, GO:0030864=IDA, GO:0045892=IDA, GO:0010314=IDA} negative regulation of transcription, DNA-dependent, positive regulation of abscisic acid mediated signaling pathway cortical actin cytoskeleton, cytoplasm, cytosol, nucleus, plasma membrane ATP binding, GTP binding, catalytic activity, phosphatidylinositol-3-phosphate binding, phosphatidylinositol-4-phosphate binding, phosphatidylinositol-5-phosphate binding Human LAP3 HPA UniProtKB {GO:0005802=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0000287=GO_REF:0000029, GO:0030145=GO_REF:0000029, GO:0004177=PMID:1908238, GO:0006508=PMID:1908238, GO:0005730=GO_REF:0000052, GO:0008235=PMID:1908238, GO:0008270=GO_REF:0000029, GO:0005634=GO_REF:0000052, GO:0019538=GO_REF:0000002} P28838 Cytosol aminopeptidase protein 20101115 {GO:0005802=IEA, GO:0005739=IEA, GO:0005737=IDA, GO:0000287=NAS, GO:0030145=NAS, GO:0004177=NAS, GO:0006508=NAS, GO:0005730=IDA, GO:0008235=NAS, GO:0008270=NAS, GO:0005634=IDA, GO:0019538=IEA} protein metabolic process, proteolysis cytoplasm, mitochondrion, nucleolus, nucleus, trans-Golgi network aminopeptidase activity, magnesium ion binding, manganese ion binding, metalloexopeptidase activity, zinc ion binding Human LAPTM4A UniProtKB UniProtKB {GO:0005794=PMID:10942595, GO:0006810=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0012505=GO_REF:0000039} Q15012 Lysosomal-associated transmembrane protein 4A protein 20060117 {GO:0005794=IDA, GO:0006810=IEA, GO:0016021=IEA, GO:0012505=IEA} transport Golgi apparatus, endomembrane system, integral to membrane Human LAPTM4B IntAct UniProtKB {GO:0005515=PMID:20711237, GO:0006810=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0012505=GO_REF:0000039} Q86VI4 Lysosomal-associated transmembrane protein 4B protein 20130415 {GO:0005515=IPI, GO:0006810=IEA, GO:0016021=IEA, GO:0012505=IEA} transport endomembrane system, integral to membrane protein binding Human UniProtKB:P08183 LAPTM5 PINC UniProtKB {GO:0005887=GO_REF:0000002, GO:0006810=GO_REF:0000037, GO:0005765=GO_REF:0000039, GO:0005764=PMID:8661146} Q13571 Lysosomal-associated transmembrane protein 5 protein 20030904 {GO:0005887=IEA, GO:0006810=IEA, GO:0005765=IEA, GO:0005764=TAS} transport integral to plasma membrane, lysosomal membrane, lysosome Human LARGE PINC UniProtKB {GO:0008375=PMID:9892679, GO:0030173=PMID:9892679, GO:0009101=PMID:9892679, GO:0016757=PMID:9892679, GO:0006688=PMID:9892679, GO:0006044=PMID:9892679, GO:0006486=GO_REF:0000041, GO:0046716=GO_REF:0000024} O95461 Glycosyltransferase-like protein LARGE1 protein 20050308 {GO:0008375=TAS, GO:0030173=TAS, GO:0009101=TAS, GO:0016757=TAS, GO:0006688=TAS, GO:0006044=TAS, GO:0006486=IEA, GO:0046716=ISS} N-acetylglucosamine metabolic process, glycoprotein biosynthetic process, glycosphingolipid biosynthetic process, muscle cell homeostasis, protein glycosylation integral to Golgi membrane acetylglucosaminyltransferase activity, transferase activity, transferring glycosyl groups Human LARP1 BHF-UCL UniProtKB {GO:0003723=GO_REF:0000037, GO:0016239=PMID:22354037} Q6PKG0 La-related protein 1 protein 20120531 {GO:0003723=IEA, GO:0016239=IMP} positive regulation of macroautophagy RNA binding Human LARP1B UniProtKB UniProtKB {GO:0003723=GO_REF:0000037, GO:0030529=GO_REF:0000038, GO:0003676=GO_REF:0000038} Q659C4 La-related protein 1B protein 20130413 {GO:0003723=IEA, GO:0030529=IEA, GO:0003676=IEA} ribonucleoprotein complex RNA binding, nucleic acid binding Human UniProtKB-KW:KW-0694 LARP4 InterPro UniProtKB {GO:0003723=GO_REF:0000037, GO:0030529=GO_REF:0000038, GO:0022604=PMID:21834987, GO:0007010=PMID:21834987, GO:0003676=GO_REF:0000002} Q96J85 C-Mpl binding protein protein 20130413 {GO:0003723=IEA, GO:0030529=IEA, GO:0022604=IMP, GO:0007010=IMP, GO:0003676=IEA} cytoskeleton organization, regulation of cell morphogenesis ribonucleoprotein complex RNA binding, nucleic acid binding Human InterPro:IPR000504 LARP4B UniProtKB UniProtKB {GO:0042788=PMID:20573744, GO:0010494=PMID:20573744, GO:0003723=GO_REF:0000037, GO:0045727=PMID:20573744, GO:0005829=PMID:20573744} Q92615 La-related protein 4B protein 20130208 {GO:0042788=IDA, GO:0010494=IDA, GO:0003723=IEA, GO:0045727=IMP, GO:0005829=IDA} positive regulation of translation cytoplasmic stress granule, cytosol, polysomal ribosome RNA binding Human LARP6 HPA UniProtKB {GO:0006396=GO_REF:0000002, GO:0005794=GO_REF:0000052, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0030529=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006417=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q9BRS8 La-related protein 6 protein 20101115 {GO:0006396=IEA, GO:0005794=IDA, GO:0000166=IEA, GO:0003723=IEA, GO:0030529=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006417=IEA, GO:0043231=IDA} RNA processing, regulation of translation Golgi apparatus, intracellular membrane-bounded organelle, nucleolus, nucleus, ribonucleoprotein complex RNA binding, nucleotide binding Human LARP7 HPA UniProtKB {GO:0006396=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0000166=GO_REF:0000002, GO:0030529=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005654=GO_REF:0000039, GO:0005634=GO_REF:0000052} Q4G0J3 La-related protein 7 protein 20111111 {GO:0006396=IEA, GO:0005737=IDA, GO:0000166=IEA, GO:0030529=IEA, GO:0003723=IEA, GO:0005654=IEA, GO:0005634=IDA} RNA processing cytoplasm, nucleoplasm, nucleus, ribonucleoprotein complex RNA binding, nucleotide binding Human LARS IntAct UniProtKB {GO:0005515=PMID:22424946, GO:0010467=Reactome:REACT_71, GO:0005737=GO_REF:0000002, GO:0002161=GO_REF:0000002, GO:0004823=Reactome:REACT_15504, GO:0005524=GO_REF:0000037, GO:0006429=GO_REF:0000002, GO:0006418=Reactome:REACT_15482, GO:0005829=Reactome:REACT_15516} Q9P2J5 Leucine--tRNA ligase, cytoplasmic protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0005737=IEA, GO:0002161=IEA, GO:0004823=TAS, GO:0005524=IEA, GO:0006429=IEA, GO:0006418=TAS, GO:0005829=TAS} gene expression, leucyl-tRNA aminoacylation, tRNA aminoacylation for protein translation cytoplasm, cytosol ATP binding, aminoacyl-tRNA editing activity, leucine-tRNA ligase activity, protein binding Human UniProtKB:Q9NQL2 LARS2 Reactome UniProtKB {GO:0005739=GO_REF:0000019, GO:0010467=Reactome:REACT_71, GO:0002161=GO_REF:0000002, GO:0005737=GO_REF:0000002, GO:0005759=Reactome:REACT_15357, GO:0004823=GO_REF:0000003, GO:0006429=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0006418=Reactome:REACT_15482} Q15031 Probable leucine--tRNA ligase, mitochondrial protein 20130301 {GO:0005739=IEA, GO:0010467=TAS, GO:0002161=IEA, GO:0005737=IEA, GO:0005759=TAS, GO:0004823=IEA, GO:0006429=IEA, GO:0005524=IEA, GO:0006418=TAS} gene expression, leucyl-tRNA aminoacylation, tRNA aminoacylation for protein translation cytoplasm, mitochondrial matrix, mitochondrion ATP binding, aminoacyl-tRNA editing activity, leucine-tRNA ligase activity Human LAS1L HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0071339=PMID:15960975, GO:0006364=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9Y4W2 Ribosomal biogenesis protein LAS1L protein 20111111 {GO:0005737=IDA, GO:0071339=IDA, GO:0006364=IEA, GO:0005730=IDA, GO:0005634=IDA} rRNA processing MLL1 complex, cytoplasm, nucleolus, nucleus Human LASP1 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0051015=GO_REF:0000019, GO:0015075=GO_REF:0000024, GO:0005070=PMID:7589475, GO:0008270=GO_REF:0000002, GO:0030864=GO_REF:0000024, GO:0005925=GO_REF:0000019, GO:0006811=GO_REF:0000024} Q14847 LIM and SH3 domain protein 1 protein 20130415 {GO:0005515=IPI, GO:0051015=IEA, GO:0015075=ISS, GO:0005070=TAS, GO:0008270=IEA, GO:0030864=ISS, GO:0005925=IEA, GO:0006811=ISS} ion transport cortical actin cytoskeleton, focal adhesion SH3/SH2 adaptor activity, actin filament binding, ion transmembrane transporter activity, protein binding, zinc ion binding Human UniProtKB:Q99750 LAT BHF-UCL UniProtKB {GO:0001772=PMID:12646565, GO:0005515=PMID:14722116, GO:0050852=Reactome:REACT_12526, GO:0010467=GO_REF:0000019, GO:0043303=GO_REF:0000037, GO:0019722=PMID:12646565, GO:0050863=PMID:12646565, GO:0005886=Reactome:REACT_147838, GO:0019901=PMID:12186560, GO:0030168=Reactome:REACT_798, GO:0007265=PMID:12646565, GO:0035556=PMID:12646565, GO:0007165=GO_REF:0000002, GO:0006955=PMID:15100278, GO:0042110=PMID:12186560, GO:0006954=GO_REF:0000019, GO:0008180=GO_REF:0000024, GO:0016020=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0007229=PMID:15100278, GO:0045087=Reactome:REACT_6802, GO:0005070=PMID:9489702, GO:0045121=PMID:14722116, GO:0016021=PMID:12646565} O43561 Linker for activation of T-cells family member 1 protein 20090109 {GO:0001772=IDA, GO:0005515=IPI, GO:0050852=TAS, GO:0010467=IEA, GO:0043303=IEA, GO:0019722=IMP, GO:0050863=IMP, GO:0005886=TAS, GO:0019901=IPI, GO:0030168=TAS, GO:0007265=IMP, GO:0035556=IDA, GO:0007165=IEA, GO:0006955=IDA, GO:0042110=TAS, GO:0006954=IEA, GO:0008180=ISS, GO:0016020=IEA, GO:0007596=TAS, GO:0007229=IDA, GO:0045087=TAS, GO:0005070=IDA, GO:0045121=TAS, GO:0016021=IDA} Ras protein signal transduction, T cell activation, T cell receptor signaling pathway, blood coagulation, calcium-mediated signaling, gene expression, immune response, inflammatory response, innate immune response, integrin-mediated signaling pathway, intracellular signal transduction, mast cell degranulation, platelet activation, regulation of T cell activation, signal transduction immunological synapse, integral to membrane, membrane, membrane raft, plasma membrane, signalosome SH3/SH2 adaptor activity, protein binding, protein kinase binding Human UniProtKB:Q60631 LAT2 HGNC UniProtKB {GO:0050853=PMID:12514734, GO:0005515=PMID:14722116, GO:0035556=PMID:14722116, GO:0042113=PMID:12514734, GO:0043303=GO_REF:0000037, GO:0019722=PMID:14722116, GO:0005886=GO_REF:0000039, GO:0045121=PMID:12486104, GO:0016021=GO_REF:0000037, GO:0042169=PMID:14722116} Q9GZY6 Linker for activation of T-cells family member 2 protein 20050413 {GO:0050853=IDA, GO:0005515=IPI, GO:0035556=IGI, GO:0042113=IDA, GO:0043303=IEA, GO:0019722=IGI, GO:0005886=IEA, GO:0045121=IDA, GO:0016021=IEA, GO:0042169=IMP} B cell activation, B cell receptor signaling pathway, calcium-mediated signaling, intracellular signal transduction, mast cell degranulation integral to membrane, membrane raft, plasma membrane SH2 domain binding, protein binding Human LATS1 BHF-UCL UniProtKB {GO:0005515=PMID:20412773, GO:0000287=PMID:10518011, GO:0019901=PMID:19927127, GO:0005815=GO_REF:0000039, GO:0000819=PMID:15122335, GO:0045736=PMID:9988268, GO:0051220=PMID:20412773, GO:0035329=PMID:20412773, GO:0005524=PMID:10518011, GO:0005829=Reactome:REACT_118858, GO:0033138=PMID:20412773, GO:0007067=GO_REF:0000037, GO:0000922=PMID:10518011, GO:0030833=PMID:15220930, GO:0009755=GO_REF:0000024, GO:0030216=GO_REF:0000019, GO:0004674=PMID:20412773, GO:0000086=PMID:15122335, GO:0043254=PMID:20412773, GO:0006468=PMID:10518011, GO:0090090=PMID:20412773, GO:0051301=GO_REF:0000037} O95835 Serine/threonine-protein kinase LATS1 protein 20100721 {GO:0005515=IPI, GO:0000287=IDA, GO:0019901=IPI, GO:0005815=IEA, GO:0000819=IDA, GO:0045736=IDA, GO:0051220=IMP, GO:0035329=IDA, GO:0005524=IDA, GO:0005829=TAS, GO:0033138=IDA, GO:0007067=IEA, GO:0000922=IDA, GO:0030833=IDA, GO:0009755=ISS, GO:0030216=IEA, GO:0004674=IDA, GO:0000086=IDA, GO:0043254=IMP, GO:0006468=IDA, GO:0090090=IMP, GO:0051301=IEA} G2/M transition of mitotic cell cycle, cell division, cytoplasmic sequestering of protein, hippo signaling cascade, hormone-mediated signaling pathway, keratinocyte differentiation, mitosis, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cyclin-dependent protein serine/threonine kinase activity, positive regulation of peptidyl-serine phosphorylation, protein phosphorylation, regulation of actin filament polymerization, regulation of protein complex assembly, sister chromatid segregation cytosol, microtubule organizing center, spindle pole ATP binding, magnesium ion binding, protein binding, protein kinase binding, protein serine/threonine kinase activity Human LATS2 BHF-UCL UniProtKB {GO:0005515=PMID:19739119, GO:0046620=GO_REF:0000019, GO:0005815=GO_REF:0000039, GO:0045736=PMID:12853976, GO:0005634=PMID:10673337, GO:0035329=PMID:20412773, GO:0005524=PMID:10871863, GO:0046872=GO_REF:0000037, GO:0007243=PMID:10871863, GO:0005829=Reactome:REACT_118858, GO:0000922=PMID:12853976, GO:0000082=PMID:12853976, GO:0007067=GO_REF:0000037, GO:0009755=PMID:15131260, GO:0030216=GO_REF:0000019, GO:0004674=Reactome:REACT_118829, GO:0006468=PMID:10871863, GO:0034613=GO_REF:0000019, GO:0090090=PMID:20412773, GO:0051301=GO_REF:0000037} Q9NRM7 Serine/threonine-protein kinase LATS2 protein 20100721 {GO:0005515=IPI, GO:0046620=IEA, GO:0005815=IEA, GO:0045736=IDA, GO:0005634=IDA, GO:0035329=IDA, GO:0005524=IDA, GO:0046872=IEA, GO:0007243=IDA, GO:0005829=TAS, GO:0000922=IDA, GO:0000082=IDA, GO:0007067=IEA, GO:0009755=IDA, GO:0030216=IEA, GO:0004674=TAS, GO:0006468=IDA, GO:0034613=IEA, GO:0090090=IMP, GO:0051301=IEA} G1/S transition of mitotic cell cycle, cell division, cellular protein localization, hippo signaling cascade, hormone-mediated signaling pathway, intracellular protein kinase cascade, keratinocyte differentiation, mitosis, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cyclin-dependent protein serine/threonine kinase activity, protein phosphorylation, regulation of organ growth cytosol, microtubule organizing center, nucleus, spindle pole ATP binding, metal ion binding, protein binding, protein serine/threonine kinase activity Human LAX1 HPA UniProtKB {GO:0005515=PMID:12359715, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0019901=PMID:12359715, GO:0050868=PMID:12359715, GO:0050851=GO_REF:0000019, GO:0035556=PMID:12359715, GO:0000188=PMID:12359715, GO:0042113=PMID:12359715, GO:0006955=PMID:12359715, GO:0005737=GO_REF:0000052, GO:0045121=PMID:12359715, GO:0016021=PMID:12359715, GO:0042169=PMID:12359715, GO:0048305=GO_REF:0000019} Q8IWV1 Lymphocyte transmembrane adapter 1 protein 20080205 {GO:0005515=IPI, GO:0005794=IDA, GO:0005886=IDA, GO:0019901=IDA, GO:0050868=IDA, GO:0050851=IEA, GO:0035556=IDA, GO:0000188=IMP, GO:0042113=IDA, GO:0006955=IDA, GO:0005737=IDA, GO:0045121=IDA, GO:0016021=IDA, GO:0042169=IDA, GO:0048305=IEA} B cell activation, antigen receptor-mediated signaling pathway, immune response, immunoglobulin secretion, inactivation of MAPK activity, intracellular signal transduction, negative regulation of T cell activation Golgi apparatus, cytoplasm, integral to membrane, membrane raft, plasma membrane SH2 domain binding, protein binding, protein kinase binding Human LAYN HGNC UniProtKB {GO:0009986=GO_REF:0000024, GO:0005540=PMID:11294894, GO:0030246=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005925=GO_REF:0000024, GO:0001726=GO_REF:0000024} Q6UX15 Layilin protein 20051207 {GO:0009986=ISS, GO:0005540=IDA, GO:0030246=IEA, GO:0016021=IEA, GO:0005925=ISS, GO:0001726=ISS} cell surface, focal adhesion, integral to membrane, ruffle carbohydrate binding, hyaluronic acid binding Human UniProtKB:Q9Z209 LBH HPA UniProtKB {GO:0005737=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0007275=GO_REF:0000037, GO:0005634=GO_REF:0000019, GO:0045893=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q53QV2 Protein LBH protein 20101115 {GO:0005737=IEA, GO:0005730=IDA, GO:0007275=IEA, GO:0005634=IEA, GO:0045893=IEA, GO:0006351=IEA, GO:0043231=IDA} multicellular organismal development, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, intracellular membrane-bounded organelle, nucleolus, nucleus Human LBP BHF-UCL UniProtKB {GO:0032755=PMID:8409400, GO:0034145=PMID:11528597, GO:0005515=PMID:21988832, GO:0043498=PMID:2477488, GO:0034142=Reactome:REACT_6894, GO:0070891=PMID:12594207, GO:0043032=PMID:8409400, GO:0050830=PMID:12932360, GO:0005615=PMID:2477488, GO:0032757=PMID:8409400, GO:0060265=GO_REF:0000024, GO:0002281=PMID:2402637, GO:0032496=PMID:11739189, GO:0044130=GO_REF:0000019, GO:0031663=PMID:8409400, GO:0008228=PMID:2477488, GO:0032760=PMID:8409400, GO:0042535=GO_REF:0000019, GO:0005102=PMID:2477488, GO:0032720=PMID:11739189, GO:0005576=Reactome:REACT_6902, GO:0032722=GO_REF:0000019, GO:0006953=PMID:2477488, GO:0002224=Reactome:REACT_6966, GO:0015920=PMID:8985160, GO:0051636=PMID:11528597, GO:0001530=PMID:2477488, GO:0002232=GO_REF:0000019, GO:0050829=PMID:2402637, GO:0071223=PMID:12594207, GO:0006968=PMID:2402637, GO:0071222=PMID:12594207, GO:0045087=PMID:12932360, GO:0051637=PMID:12932360, GO:0090023=GO_REF:0000019, GO:0032490=PMID:11528597} P18428 Lipopolysaccharide-binding protein protein 20080708 {GO:0032755=IDA, GO:0034145=IDA, GO:0005515=IPI, GO:0043498=ISS, GO:0034142=TAS, GO:0070891=IDA, GO:0043032=IDA, GO:0050830=IC, GO:0005615=ISS, GO:0032757=IDA, GO:0060265=ISS, GO:0002281=ISS, GO:0032496=IDA, GO:0044130=IEA, GO:0031663=IDA, GO:0008228=ISS, GO:0032760=IDA, GO:0042535=IEA, GO:0005102=ISS, GO:0032720=IDA, GO:0005576=TAS, GO:0032722=IEA, GO:0006953=ISS, GO:0002224=TAS, GO:0015920=IDA, GO:0051636=IDA, GO:0001530=ISS, GO:0002232=IEA, GO:0050829=ISS, GO:0071223=IDA, GO:0006968=ISS, GO:0071222=IDA, GO:0045087=IC, GO:0051637=IDA, GO:0090023=IEA, GO:0032490=IDA} acute-phase response, cellular defense response, cellular response to lipopolysaccharide, cellular response to lipoteichoic acid, defense response to Gram-negative bacterium, defense response to Gram-positive bacterium, detection of molecule of bacterial origin, innate immune response, leukocyte chemotaxis involved in inflammatory response, lipopolysaccharide transport, lipopolysaccharide-mediated signaling pathway, macrophage activation involved in immune response, negative regulation of growth of symbiont in host, negative regulation of tumor necrosis factor production, opsonization, positive regulation of chemokine production, positive regulation of interleukin-6 production, positive regulation of interleukin-8 production, positive regulation of macrophage activation, positive regulation of neutrophil chemotaxis, positive regulation of respiratory burst involved in inflammatory response, positive regulation of toll-like receptor 4 signaling pathway, positive regulation of tumor necrosis factor biosynthetic process, positive regulation of tumor necrosis factor production, response to lipopolysaccharide, toll-like receptor 4 signaling pathway, toll-like receptor signaling pathway extracellular region, extracellular space Gram-negative bacterial cell surface binding, Gram-positive bacterial cell surface binding, cell surface binding, lipopolysaccharide binding, lipoteichoic acid binding, protein binding, receptor binding Human LBR BHF-UCL UniProtKB {GO:0005515=PMID:8663349, GO:0006695=Reactome:REACT_9405, GO:0031965=GO_REF:0000052, GO:0070087=PMID:15882967, GO:0005635=Reactome:REACT_9995, GO:0044281=Reactome:REACT_111217, GO:0016628=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0005639=PMID:8157662, GO:0005739=GO_REF:0000052, GO:0016020=GO_REF:0000002, GO:0016021=PMID:15698635, GO:0005521=PMID:8157662} Q14739 Lamin-B receptor protein 20100127 {GO:0005515=IPI, GO:0006695=TAS, GO:0031965=IDA, GO:0070087=IPI, GO:0005635=TAS, GO:0044281=TAS, GO:0016628=IEA, GO:0003677=IEA, GO:0005639=TAS, GO:0005739=IDA, GO:0016020=IEA, GO:0016021=IDA, GO:0005521=TAS} cholesterol biosynthetic process, small molecule metabolic process integral to membrane, integral to nuclear inner membrane, membrane, mitochondrion, nuclear envelope, nuclear membrane DNA binding, chromo shadow domain binding, lamin binding, oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor, protein binding Human UniProtKB:P45973 LBX1 PINC UniProtKB {GO:0001947=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0000976=GO_REF:0000002, GO:0008285=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0007517=GO_REF:0000037, GO:0045665=GO_REF:0000019, GO:0048664=GO_REF:0000019, GO:0009653=PMID:8645601, GO:0006351=GO_REF:0000037, GO:0021920=GO_REF:0000019} P52954 Transcription factor LBX1 protein 20031119 {GO:0001947=IEA, GO:0005667=IEA, GO:0000976=IEA, GO:0008285=IEA, GO:0003700=IEA, GO:0007517=IEA, GO:0045665=IEA, GO:0048664=IEA, GO:0009653=TAS, GO:0006351=IEA, GO:0021920=IEA} anatomical structure morphogenesis, heart looping, muscle organ development, negative regulation of cell proliferation, negative regulation of neuron differentiation, neuron fate determination, regulation of transcription from RNA polymerase II promoter involved in spinal cord association neuron specification, transcription, DNA-dependent transcription factor complex sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding Human LCAT BHF-UCL UniProtKB {GO:0042632=PMID:4335615, GO:0006629=Reactome:REACT_602, GO:0005515=PMID:11435418, GO:0008374=GO_REF:0000002, GO:0043691=PMID:4335615, GO:0005576=Reactome:REACT_13735, GO:0030301=PMID:10559507, GO:0044281=Reactome:REACT_111217, GO:0005615=PMID:3458198, GO:0034372=PMID:15654758, GO:0034364=PMID:3104518, GO:0004607=PMID:4335615, GO:0034375=PMID:4335615, GO:0042157=Reactome:REACT_13621, GO:0034435=PMID:4335615, GO:0034186=PMID:1587806, GO:0006644=PMID:4335615, GO:0090107=GO_REF:0000019, GO:0006656=PMID:11966470, GO:0042158=GO_REF:0000019, GO:0008203=PMID:4335615} P04180 Phosphatidylcholine-sterol acyltransferase protein 20080801 {GO:0042632=IDA, GO:0006629=TAS, GO:0005515=IPI, GO:0008374=IEA, GO:0043691=IDA, GO:0005576=TAS, GO:0030301=IDA, GO:0044281=TAS, GO:0005615=IDA, GO:0034372=IDA, GO:0034364=IDA, GO:0004607=IDA, GO:0034375=IDA, GO:0042157=TAS, GO:0034435=IDA, GO:0034186=IPI, GO:0006644=IDA, GO:0090107=IEA, GO:0006656=IDA, GO:0042158=IEA, GO:0008203=IDA} cholesterol esterification, cholesterol homeostasis, cholesterol metabolic process, cholesterol transport, high-density lipoprotein particle remodeling, lipid metabolic process, lipoprotein biosynthetic process, lipoprotein metabolic process, phosphatidylcholine biosynthetic process, phospholipid metabolic process, regulation of high-density lipoprotein particle assembly, reverse cholesterol transport, small molecule metabolic process, very-low-density lipoprotein particle remodeling extracellular region, extracellular space, high-density lipoprotein particle O-acyltransferase activity, apolipoprotein A-I binding, phosphatidylcholine-sterol O-acyltransferase activity, protein binding Human UniProtKB:P02647 LCK UniProtKB UniProtKB {GO:0005515=PMID:22939624, GO:0042542=GO_REF:0000019, GO:0006882=GO_REF:0000024, GO:0050900=Reactome:REACT_12051, GO:0032403=GO_REF:0000019, GO:0010043=GO_REF:0000019, GO:0046777=GO_REF:0000019, GO:0001948=PMID:8650207, GO:0042609=PMID:7486703, GO:0070474=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0051117=PMID:15671290, GO:0042169=GO_REF:0000024, GO:0000242=PMID:7513706, GO:0051209=GO_REF:0000024, GO:0019901=PMID:8618896, GO:0045588=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0018108=GO_REF:0000019, GO:0051249=PMID:7852312, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0050870=GO_REF:0000024, GO:0045121=GO_REF:0000024, GO:0043548=PMID:7504174, GO:0050853=GO_REF:0000019, GO:0050852=Reactome:REACT_12526, GO:0005886=Reactome:REACT_12640, GO:0050856=GO_REF:0000019, GO:0031295=Reactome:REACT_19344, GO:0042523=GO_REF:0000019, GO:0030139=GO_REF:0000019, GO:0003823=GO_REF:0000019, GO:0005829=Reactome:REACT_147879, GO:0016032=Reactome:REACT_6185, GO:0004722=GO_REF:0000024, GO:0030097=PMID:12884910, GO:0001772=PMID:20007709, GO:0048011=Reactome:REACT_11061, GO:0042610=PMID:2470098, GO:0006919=GO_REF:0000024, GO:0048015=Reactome:REACT_12464, GO:0042493=GO_REF:0000024, GO:0006915=GO_REF:0000019, GO:0006917=PMID:16116473, GO:0050862=PMID:12614355, GO:0008022=PMID:16245368, GO:0005524=GO_REF:0000038, GO:0050690=Reactome:REACT_11166, GO:0009612=GO_REF:0000019, GO:0010628=GO_REF:0000019, GO:0030217=PMID:1579166, GO:0007596=Reactome:REACT_604, GO:0019048=GO_REF:0000037, GO:0006468=PMID:214242, GO:0004713=GO_REF:0000038, GO:0004715=GO_REF:0000003} Q573B4 Tyrosine-protein kinase Lck protein 20130413 {GO:0005515=IPI, GO:0042542=IEA, GO:0006882=ISS, GO:0050900=TAS, GO:0032403=IEA, GO:0010043=IEA, GO:0046777=IEA, GO:0001948=IPI, GO:0042609=IPI, GO:0070474=IEA, GO:0007173=TAS, GO:0051117=IPI, GO:0042169=ISS, GO:0000242=IDA, GO:0051209=ISS, GO:0019901=IPI, GO:0045588=IEA, GO:0007568=IEA, GO:0030168=TAS, GO:0018108=IEA, GO:0051249=NAS, GO:0008543=TAS, GO:0045087=TAS, GO:0050870=ISS, GO:0045121=ISS, GO:0043548=IPI, GO:0050853=IEA, GO:0050852=TAS, GO:0005886=TAS, GO:0050856=IEA, GO:0031295=TAS, GO:0042523=IEA, GO:0030139=IEA, GO:0003823=IEA, GO:0005829=TAS, GO:0016032=TAS, GO:0004722=ISS, GO:0030097=NAS, GO:0001772=IDA, GO:0048011=TAS, GO:0042610=IPI, GO:0006919=ISS, GO:0048015=TAS, GO:0042493=ISS, GO:0006915=IEA, GO:0006917=IMP, GO:0050862=NAS, GO:0008022=IPI, GO:0005524=IEA, GO:0050690=TAS, GO:0009612=IEA, GO:0010628=IEA, GO:0030217=IMP, GO:0007596=TAS, GO:0019048=IEA, GO:0006468=IDA, GO:0004713=IEA, GO:0004715=IEA} B cell receptor signaling pathway, T cell costimulation, T cell differentiation, T cell receptor signaling pathway, activation of cysteine-type endopeptidase activity involved in apoptotic process, aging, apoptotic process, blood coagulation, cellular zinc ion homeostasis, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, hemopoiesis, induction of apoptosis, innate immune response, leukocyte migration, neurotrophin TRK receptor signaling pathway, peptidyl-tyrosine phosphorylation, phosphatidylinositol-mediated signaling, platelet activation, positive regulation of T cell activation, positive regulation of T cell receptor signaling pathway, positive regulation of gamma-delta T cell differentiation, positive regulation of gene expression, positive regulation of tyrosine phosphorylation of Stat5 protein, positive regulation of uterine smooth muscle contraction, protein autophosphorylation, protein phosphorylation, regulation of T cell receptor signaling pathway, regulation of defense response to virus by virus, regulation of lymphocyte activation, release of sequestered calcium ion into cytosol, response to drug, response to hydrogen peroxide, response to mechanical stimulus, response to zinc ion, viral reproduction, virus-host interaction cytosol, endocytic vesicle, immunological synapse, membrane raft, pericentriolar material, plasma membrane ATP binding, ATPase binding, CD4 receptor binding, CD8 receptor binding, SH2 domain binding, antigen binding, glycoprotein binding, non-membrane spanning protein tyrosine kinase activity, phosphatidylinositol 3-kinase binding, protein C-terminus binding, protein binding, protein complex binding, protein kinase binding, protein serine/threonine phosphatase activity, protein tyrosine kinase activity Human UniProtKB-KW:KW-0067 LCLAT1 Reactome UniProtKB {GO:0016746=GO_REF:0000002, GO:0005783=GO_REF:0000019, GO:0035965=Reactome:REACT_121006, GO:0007275=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0003841=GO_REF:0000003, GO:0016024=GO_REF:0000041, GO:0005789=Reactome:REACT_121307, GO:0019432=Reactome:REACT_1190, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0006654=Reactome:REACT_120906, GO:0044255=Reactome:REACT_22279, GO:0046474=Reactome:REACT_121401} Q6UWP7 Lysocardiolipin acyltransferase 1 protein 20130301 {GO:0016746=IEA, GO:0005783=IEA, GO:0035965=TAS, GO:0007275=IEA, GO:0044281=TAS, GO:0003841=IEA, GO:0016024=IEA, GO:0005789=TAS, GO:0019432=TAS, GO:0016021=IEA, GO:0006644=TAS, GO:0006654=TAS, GO:0044255=TAS, GO:0046474=TAS} CDP-diacylglycerol biosynthetic process, cardiolipin acyl-chain remodeling, cellular lipid metabolic process, glycerophospholipid biosynthetic process, multicellular organismal development, phosphatidic acid biosynthetic process, phospholipid metabolic process, small molecule metabolic process, triglyceride biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane 1-acylglycerol-3-phosphate O-acyltransferase activity, transferase activity, transferring acyl groups Human LCMT1 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0031333=PMID:17724024, GO:0006481=PMID:10600115, GO:0008168=GO_REF:0000002, GO:0090266=PMID:17724024, GO:0006479=PMID:17724024, GO:0003880=PMID:10600115, GO:0042981=PMID:17724024, GO:0008757=PMID:10600115, GO:0006464=PMID:10600115} Q9UIC8 Leucine carboxyl methyltransferase 1 protein 20130415 {GO:0005515=IPI, GO:0031333=IMP, GO:0006481=IDA, GO:0008168=IEA, GO:0090266=IMP, GO:0006479=IMP, GO:0003880=IDA, GO:0042981=IMP, GO:0008757=TAS, GO:0006464=TAS} C-terminal protein methylation, cellular protein modification process, negative regulation of protein complex assembly, protein methylation, regulation of apoptotic process, regulation of mitotic cell cycle spindle assembly checkpoint S-adenosylmethionine-dependent methyltransferase activity, methyltransferase activity, protein C-terminal carboxyl O-methyltransferase activity, protein binding Human UniProtKB:P51116 LCMT2 UniProtKB UniProtKB {GO:0005515=PMID:12853982, GO:0008168=GO_REF:0000037, GO:0008033=GO_REF:0000037} O60294 Leucine carboxyl methyltransferase 2 protein 20050609 {GO:0005515=IPI, GO:0008168=IEA, GO:0008033=IEA} tRNA processing methyltransferase activity, protein binding Human UniProtKB:Q7Z419 LCN1 PINC UniProtKB {GO:0004869=PMID:8999869, GO:0050909=GO_REF:0000037, GO:0006508=PMID:8999869, GO:0006810=GO_REF:0000037, GO:0005576=GO_REF:0000039, GO:0050896=GO_REF:0000037} P31025 Lipocalin-1 protein 20030904 {GO:0004869=TAS, GO:0050909=IEA, GO:0006508=TAS, GO:0006810=IEA, GO:0005576=IEA, GO:0050896=IEA} proteolysis, response to stimulus, sensory perception of taste, transport extracellular region cysteine-type endopeptidase inhibitor activity Human LCN2 HPA UniProtKB {GO:0005215=GO_REF:0000002, GO:0070301=GO_REF:0000019, GO:0002020=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0070207=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0031669=GO_REF:0000019, GO:0071356=GO_REF:0000019, GO:0015891=GO_REF:0000024, GO:0006811=GO_REF:0000037, GO:0005506=GO_REF:0000024, GO:0042493=GO_REF:0000019, GO:0036094=GO_REF:0000002, GO:0006915=GO_REF:0000037, GO:0009635=GO_REF:0000019, GO:0005576=GO_REF:0000024, GO:0042981=GO_REF:0000024, GO:0009615=GO_REF:0000019, GO:0010628=GO_REF:0000019, GO:0071222=GO_REF:0000019, GO:0031346=GO_REF:0000019, GO:0045087=GO_REF:0000024, GO:0071347=GO_REF:0000019} P80188 Neutrophil gelatinase-associated lipocalin protein 20080205 {GO:0005215=IEA, GO:0070301=IEA, GO:0002020=IEA, GO:0005615=IEA, GO:0042803=IEA, GO:0005829=IEA, GO:0070207=IEA, GO:0005737=IDA, GO:0031669=IEA, GO:0071356=IEA, GO:0015891=ISS, GO:0006811=IEA, GO:0005506=ISS, GO:0042493=IEA, GO:0036094=IEA, GO:0006915=IEA, GO:0009635=IEA, GO:0005576=ISS, GO:0042981=ISS, GO:0009615=IEA, GO:0010628=IEA, GO:0071222=IEA, GO:0031346=IEA, GO:0045087=ISS, GO:0071347=IEA} apoptotic process, cellular response to hydrogen peroxide, cellular response to interleukin-1, cellular response to lipopolysaccharide, cellular response to nutrient levels, cellular response to tumor necrosis factor, innate immune response, ion transport, positive regulation of cell projection organization, positive regulation of gene expression, protein homotrimerization, regulation of apoptotic process, response to drug, response to herbicide, response to virus, siderophore transport cytoplasm, cytosol, extracellular region, extracellular space iron ion binding, protease binding, protein homodimerization activity, small molecule binding, transporter activity Human LCOR UniProtKB UniProtKB {GO:0003700=GO_REF:0000019, GO:0006366=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0000122=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0008134=GO_REF:0000019} Q96JN0 Ligand-dependent corepressor protein 20130413 {GO:0003700=IEA, GO:0006366=IEA, GO:0005634=IEA, GO:0000122=IEA, GO:0003677=IEA, GO:0008134=IEA} negative regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter nucleus DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human UniProtKB-SubCell:SL-0191 LCORL UniProtKB UniProtKB {GO:0006366=GO_REF:0000019, GO:0006357=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037} Q8N3X6 Ligand-dependent nuclear receptor corepressor-like protein protein 20130413 {GO:0006366=IEA, GO:0006357=IEA, GO:0005634=IEA, GO:0003677=IEA} regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter nucleus DNA binding Human UniProtKB-SubCell:SL-0191 LCP1 HPA UniProtKB {GO:0030054=GO_REF:0000039, GO:0005886=GO_REF:0000052, GO:0005884=GO_REF:0000019, GO:0031100=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0003779=PMID:2252891, GO:0001891=GO_REF:0000019, GO:0032587=GO_REF:0000039, GO:0015629=GO_REF:0000052, GO:0001726=GO_REF:0000019, GO:0042802=GO_REF:0000019, GO:0005829=PMID:17294403, GO:0005737=GO_REF:0000052, GO:0051015=GO_REF:0000019, GO:0033157=PMID:17294403, GO:0051017=GO_REF:0000019, GO:0002286=PMID:17294403} Q5TBN5 Plastin-2 protein 20101115 {GO:0030054=IEA, GO:0005886=IDA, GO:0005884=IEA, GO:0031100=IEA, GO:0005509=IEA, GO:0003779=NAS, GO:0001891=IEA, GO:0032587=IEA, GO:0015629=IDA, GO:0001726=IEA, GO:0042802=IEA, GO:0005829=IDA, GO:0005737=IDA, GO:0051015=IEA, GO:0033157=IDA, GO:0051017=IEA, GO:0002286=IDA} T cell activation involved in immune response, actin filament bundle assembly, organ regeneration, regulation of intracellular protein transport actin cytoskeleton, actin filament, cell junction, cytoplasm, cytosol, phagocytic cup, plasma membrane, ruffle, ruffle membrane actin binding, actin filament binding, calcium ion binding, identical protein binding Human LCP2 IntAct UniProtKB {GO:0005515=PMID:21983831, GO:0050852=Reactome:REACT_12526, GO:0006955=PMID:7706237, GO:0050663=GO_REF:0000019, GO:0045576=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0030168=Reactome:REACT_798, GO:0007169=PMID:7706237, GO:0005829=Reactome:REACT_147838} Q13094 Lymphocyte cytosolic protein 2 protein 20130415 {GO:0005515=IPI, GO:0050852=TAS, GO:0006955=TAS, GO:0050663=IEA, GO:0045576=IEA, GO:0007596=TAS, GO:0045087=TAS, GO:0030168=TAS, GO:0007169=TAS, GO:0005829=TAS} T cell receptor signaling pathway, blood coagulation, cytokine secretion, immune response, innate immune response, mast cell activation, platelet activation, transmembrane receptor protein tyrosine kinase signaling pathway cytosol protein binding Human UniProtKB:Q99JP0 LCT Reactome UniProtKB {GO:0017042=GO_REF:0000003, GO:0016324=GO_REF:0000039, GO:0005886=Reactome:REACT_9455, GO:0016020=PMID:2460343, GO:0005887=PMID:2460343, GO:0005975=Reactome:REACT_474, GO:0044245=Reactome:REACT_9472, GO:0000016=Reactome:REACT_9455, GO:0044281=Reactome:REACT_111217, GO:0004553=GO_REF:0000002} P09848 Lactase-phlorizin hydrolase protein 20061103 {GO:0017042=IEA, GO:0016324=IEA, GO:0005886=TAS, GO:0016020=TAS, GO:0005887=TAS, GO:0005975=TAS, GO:0044245=TAS, GO:0000016=TAS, GO:0044281=TAS, GO:0004553=IEA} carbohydrate metabolic process, polysaccharide digestion, small molecule metabolic process apical plasma membrane, integral to plasma membrane, membrane, plasma membrane glycosylceramidase activity, hydrolase activity, hydrolyzing O-glycosyl compounds, lactase activity Human LDB1 BHF-UCL UniProtKB {GO:0000790=PMID:20855495, GO:0006366=GO_REF:0000019, GO:0005634=GO_REF:0000024, GO:0043621=GO_REF:0000019, GO:0042803=GO_REF:0000024, GO:0022607=GO_REF:0000019, GO:0010669=GO_REF:0000019, GO:0009948=GO_REF:0000019, GO:0032784=GO_REF:0000024, GO:0021702=GO_REF:0000019, GO:0005911=GO_REF:0000019, GO:0045944=PMID:20855495, GO:0030182=GO_REF:0000024, GO:0030274=PMID:12792813, GO:0046985=GO_REF:0000024, GO:0043973=GO_REF:0000024, GO:0016055=GO_REF:0000019, GO:0035019=GO_REF:0000019, GO:0001942=GO_REF:0000019, GO:0001102=PMID:16314316, GO:0005667=PMID:16314316, GO:0006355=PMID:12792813, GO:0000972=GO_REF:0000024, GO:0003714=PMID:9391090, GO:0007275=PMID:12792813, GO:0001702=GO_REF:0000019, GO:0006351=PMID:12792813, GO:0045785=GO_REF:0000019, GO:0043234=GO_REF:0000024, GO:0045647=GO_REF:0000024, GO:0003682=GO_REF:0000019, GO:0060322=GO_REF:0000019, GO:0019899=GO_REF:0000019, GO:0001158=GO_REF:0000019, GO:0045892=PMID:10767331} Q86U70 LIM domain-binding protein 1 protein 20110205 {GO:0000790=IDA, GO:0006366=IEA, GO:0005634=ISS, GO:0043621=IEA, GO:0042803=ISS, GO:0022607=IEA, GO:0010669=IEA, GO:0009948=IEA, GO:0032784=ISS, GO:0021702=IEA, GO:0005911=IEA, GO:0045944=IMP, GO:0030182=ISS, GO:0030274=IPI, GO:0046985=ISS, GO:0043973=ISS, GO:0016055=IEA, GO:0035019=IEA, GO:0001942=IEA, GO:0001102=IPI, GO:0005667=IDA, GO:0006355=NAS, GO:0000972=ISS, GO:0003714=TAS, GO:0007275=NAS, GO:0001702=IEA, GO:0006351=NAS, GO:0045785=IEA, GO:0043234=ISS, GO:0045647=ISS, GO:0003682=IEA, GO:0060322=IEA, GO:0019899=IEA, GO:0001158=IEA, GO:0045892=IDA} Wnt receptor signaling pathway, anterior/posterior axis specification, cellular component assembly, cerebellar Purkinje cell differentiation, epithelial structure maintenance, gastrulation with mouth forming second, hair follicle development, head development, histone H3-K4 acetylation, multicellular organismal development, negative regulation of erythrocyte differentiation, negative regulation of transcription, DNA-dependent, neuron differentiation, positive regulation of cell adhesion, positive regulation of hemoglobin biosynthetic process, positive regulation of transcription from RNA polymerase II promoter, regulation of DNA-dependent transcription, elongation, regulation of transcription, DNA-dependent, somatic stem cell maintenance, transcription from RNA polymerase II promoter, transcription, DNA-dependent, transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery cell-cell junction, nuclear chromatin, nucleus, protein complex, transcription factor complex LIM domain binding, RNA polymerase II activating transcription factor binding, chromatin binding, enhancer sequence-specific DNA binding, enzyme binding, protein homodimerization activity, protein self-association, transcription corepressor activity Human LDB2 UniProtKB UniProtKB {GO:0003712=GO_REF:0000002, GO:0005667=GO_REF:0000019, GO:0044089=GO_REF:0000019, GO:0010669=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0030274=GO_REF:0000024, GO:0005634=PMID:9853615, GO:0019899=GO_REF:0000019, GO:0035019=GO_REF:0000019, GO:0001942=GO_REF:0000019} O43679 LIM domain-binding protein 2 protein 20070124 {GO:0003712=IEA, GO:0005667=IEA, GO:0044089=IEA, GO:0010669=IEA, GO:0045944=IEA, GO:0030274=ISS, GO:0005634=IDA, GO:0019899=IEA, GO:0035019=IEA, GO:0001942=IEA} epithelial structure maintenance, hair follicle development, positive regulation of cellular component biogenesis, positive regulation of transcription from RNA polymerase II promoter, somatic stem cell maintenance nucleus, transcription factor complex LIM domain binding, enzyme binding, transcription cofactor activity Human LDB3 MGI UniProtKB {GO:0008092=PMID:17987659, GO:0005515=PMID:10427098, GO:0030018=PMID:10427098, GO:0048471=GO_REF:0000039, GO:0005080=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005856=PMID:10427098, GO:0031143=GO_REF:0000039} O75112 LIM domain-binding protein 3 protein 20130307 {GO:0008092=IPI, GO:0005515=IPI, GO:0030018=IDA, GO:0048471=IEA, GO:0005080=IEA, GO:0008270=IEA, GO:0005856=IDA, GO:0031143=IEA} Z disc, cytoskeleton, perinuclear region of cytoplasm, pseudopodium cytoskeletal protein binding, protein binding, protein kinase C binding, zinc ion binding Human LDHA Reactome UniProtKB {GO:0005739=GO_REF:0000019, GO:0005737=GO_REF:0000002, GO:0004459=PMID:1953713, GO:0044262=GO_REF:0000002, GO:0006090=Reactome:REACT_2071, GO:0031668=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0006096=PMID:1953713, GO:0005829=Reactome:REACT_1010, GO:0016616=GO_REF:0000002} P00338 L-lactate dehydrogenase A chain protein 20130213 {GO:0005739=IEA, GO:0005737=IEA, GO:0004459=NAS, GO:0044262=IEA, GO:0006090=TAS, GO:0031668=IEA, GO:0044281=TAS, GO:0006096=NAS, GO:0005829=TAS, GO:0016616=IEA} cellular carbohydrate metabolic process, cellular response to extracellular stimulus, glycolysis, pyruvate metabolic process, small molecule metabolic process cytoplasm, cytosol, mitochondrion L-lactate dehydrogenase activity, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Human LDHAL6A UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0004459=GO_REF:0000003, GO:0044262=GO_REF:0000002, GO:0006096=GO_REF:0000037} Q6ZMR3 L-lactate dehydrogenase A-like 6A protein 20130413 {GO:0005737=IEA, GO:0004459=IEA, GO:0044262=IEA, GO:0006096=IEA} cellular carbohydrate metabolic process, glycolysis cytoplasm L-lactate dehydrogenase activity Human UniProtKB-SubCell:SL-0086 LDHAL6B IntAct UniProtKB {GO:0005515=PMID:12107167, GO:0005737=GO_REF:0000002, GO:0004459=GO_REF:0000003, GO:0044262=GO_REF:0000002, GO:0006096=GO_REF:0000037} Q9BYZ2 L-lactate dehydrogenase A-like 6B protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0004459=IEA, GO:0044262=IEA, GO:0006096=IEA} cellular carbohydrate metabolic process, glycolysis cytoplasm L-lactate dehydrogenase activity, protein binding Human UniProtKB:Q14103 LDHB Reactome UniProtKB {GO:0006089=GO_REF:0000019, GO:0044262=GO_REF:0000002, GO:0019674=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0006096=GO_REF:0000037, GO:0042802=GO_REF:0000019, GO:0005829=Reactome:REACT_1010, GO:0005739=GO_REF:0000019, GO:0005737=PMID:16130169, GO:0051287=GO_REF:0000019, GO:0004459=GO_REF:0000003, GO:0006090=Reactome:REACT_2071, GO:0019900=GO_REF:0000019} P07195 L-lactate dehydrogenase B chain protein 20130213 {GO:0006089=IEA, GO:0044262=IEA, GO:0019674=IEA, GO:0044281=TAS, GO:0006096=IEA, GO:0042802=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0005737=TAS, GO:0051287=IEA, GO:0004459=IEA, GO:0006090=TAS, GO:0019900=IEA} NAD metabolic process, cellular carbohydrate metabolic process, glycolysis, lactate metabolic process, pyruvate metabolic process, small molecule metabolic process cytoplasm, cytosol, mitochondrion L-lactate dehydrogenase activity, NAD binding, identical protein binding, kinase binding Human LDHC UniProtKB UniProtKB {GO:0006754=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0019516=GO_REF:0000019, GO:0004459=GO_REF:0000003, GO:0044262=GO_REF:0000002, GO:0030317=GO_REF:0000019, GO:0019244=GO_REF:0000019, GO:0006096=GO_REF:0000037, GO:0016616=GO_REF:0000002} P07864 L-lactate dehydrogenase C chain protein 20130413 {GO:0006754=IEA, GO:0005737=IEA, GO:0019516=IEA, GO:0004459=IEA, GO:0044262=IEA, GO:0030317=IEA, GO:0019244=IEA, GO:0006096=IEA, GO:0016616=IEA} ATP biosynthetic process, cellular carbohydrate metabolic process, glycolysis, lactate biosynthetic process from pyruvate, lactate oxidation, sperm motility cytoplasm L-lactate dehydrogenase activity, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Human UniProtKB-SubCell:SL-0086 LDHD UniProtKB UniProtKB {GO:0005739=GO_REF:0000024, GO:0005515=PMID:12127981, GO:0004458=GO_REF:0000003, GO:0008762=GO_REF:0000002, GO:0050660=GO_REF:0000002, GO:0005743=GO_REF:0000019} Q86WU2 Probable D-lactate dehydrogenase, mitochondrial protein 20041006 {GO:0005739=ISS, GO:0005515=IPI, GO:0004458=IEA, GO:0008762=IEA, GO:0050660=IEA, GO:0005743=IEA} mitochondrial inner membrane, mitochondrion D-lactate dehydrogenase (cytochrome) activity, UDP-N-acetylmuramate dehydrogenase activity, flavin adenine dinucleotide binding, protein binding Human UniProtKB:Q7TNG8 LDLR BHF-UCL UniProtKB {GO:0005515=PMID:17452316, GO:0006629=Reactome:REACT_602, GO:0005886=Reactome:REACT_6940, GO:0007603=Reactome:REACT_160125, GO:0010899=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0030301=PMID:17142622, GO:0005764=PMID:15166224, GO:0005041=PMID:6091915, GO:0030299=PMID:17142622, GO:0001948=PMID:10571240, GO:0015914=GO_REF:0000024, GO:0034383=PMID:17142622, GO:0030229=PMID:8626535, GO:0034362=GO_REF:0000037, GO:0008203=GO_REF:0000019, GO:0042632=PMID:17142622, GO:0010867=GO_REF:0000024, GO:0005794=PMID:17461796, GO:0009986=PMID:17461796, GO:0005770=PMID:17461796, GO:0005509=GO_REF:0000002, GO:0030169=GO_REF:0000019, GO:0001523=Reactome:REACT_24968, GO:0006898=Reactome:REACT_6934, GO:0006897=PMID:12671190, GO:0005905=PMID:15166224, GO:0070508=GO_REF:0000024, GO:0005887=PMID:6327078, GO:0019048=GO_REF:0000037, GO:0042157=Reactome:REACT_6841, GO:0016021=GO_REF:0000038, GO:0030669=Reactome:REACT_6924, GO:0009897=PMID:15166224, GO:0042159=GO_REF:0000019, GO:0010008=Reactome:REACT_6901, GO:0005769=PMID:15166224} P01130 Low-density lipoprotein receptor protein 20090731 {GO:0005515=IPI, GO:0006629=TAS, GO:0005886=TAS, GO:0007603=TAS, GO:0010899=ISS, GO:0044281=TAS, GO:0030301=IMP, GO:0005764=IDA, GO:0005041=IDA, GO:0030299=IMP, GO:0001948=IPI, GO:0015914=ISS, GO:0034383=IMP, GO:0030229=IDA, GO:0034362=IEA, GO:0008203=IEA, GO:0042632=IMP, GO:0010867=ISS, GO:0005794=IDA, GO:0009986=IDA, GO:0005770=IDA, GO:0005509=IEA, GO:0030169=IEA, GO:0001523=TAS, GO:0006898=TAS, GO:0006897=TAS, GO:0005905=IDA, GO:0070508=ISS, GO:0005887=TAS, GO:0019048=IEA, GO:0042157=TAS, GO:0016021=IEA, GO:0030669=TAS, GO:0009897=IDA, GO:0042159=IEA, GO:0010008=TAS, GO:0005769=IDA} cholesterol homeostasis, cholesterol import, cholesterol metabolic process, cholesterol transport, endocytosis, intestinal cholesterol absorption, lipid metabolic process, lipoprotein catabolic process, lipoprotein metabolic process, low-density lipoprotein particle clearance, phospholipid transport, phototransduction, visible light, positive regulation of triglyceride biosynthetic process, receptor-mediated endocytosis, regulation of phosphatidylcholine catabolic process, retinoid metabolic process, small molecule metabolic process, virus-host interaction Golgi apparatus, cell surface, clathrin-coated endocytic vesicle membrane, coated pit, early endosome, endosome membrane, external side of plasma membrane, integral to membrane, integral to plasma membrane, late endosome, low-density lipoprotein particle, lysosome, plasma membrane calcium ion binding, glycoprotein binding, low-density lipoprotein particle binding, low-density lipoprotein receptor activity, protein binding, very-low-density lipoprotein particle receptor activity Human UniProtKB:Q8NBP7 LDLRAD3 UniProtKB UniProtKB {GO:0001540=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0070613=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0006898=GO_REF:0000019} Q86YD5 Low-density lipoprotein receptor class A domain-containing protein 3 protein 20130413 {GO:0001540=IEA, GO:0005886=IEA, GO:0070613=IEA, GO:0016021=IEA, GO:0006898=IEA} receptor-mediated endocytosis, regulation of protein processing integral to membrane, plasma membrane beta-amyloid binding Human UniProtKB-SubCell:SL-0039 LDLRAP1 GOC UniProtKB {GO:0005515=PMID:12221107, GO:0030424=GO_REF:0000024, GO:0035615=PMID:15728179, GO:0035612=PMID:15728179, GO:0005883=PMID:17727637, GO:0030159=PMID:15166224, GO:0005829=PMID:12451172, GO:0031623=PMID:15166224, GO:0090205=PMID:15166224, GO:0001540=PMID:12805363, GO:0009925=PMID:12451172, GO:0030276=PMID:12221107, GO:0006810=PMID:12451172, GO:0008203=PMID:12451172, GO:0090118=PMID:12464675, GO:0042632=PMID:15166224, GO:0035591=PMID:12221107, GO:0030121=PMID:12451172, GO:0030122=PMID:12451172, GO:0043393=PMID:15166224, GO:0005546=PMID:12451172, GO:0009967=PMID:12221107, GO:0042982=PMID:12805363, GO:0006898=PMID:14528014, GO:0048260=PMID:15166224, GO:0009898=PMID:14528014, GO:0001784=PMID:12451172, GO:0055037=PMID:14528014, GO:0005769=PMID:14528014, GO:0090003=PMID:12805363, GO:0050750=PMID:14528014} Q5SW96 Low density lipoprotein receptor adapter protein 1 protein 20130413 {GO:0005515=IPI, GO:0030424=ISS, GO:0035615=IDA, GO:0035612=IDA, GO:0005883=ISS, GO:0030159=IMP, GO:0005829=IDA, GO:0031623=IMP, GO:0090205=IC, GO:0001540=IPI, GO:0009925=IDA, GO:0030276=IDA, GO:0006810=NAS, GO:0008203=NAS, GO:0090118=IMP, GO:0042632=IMP, GO:0035591=IDA, GO:0030121=IDA, GO:0030122=IDA, GO:0043393=IMP, GO:0005546=IDA, GO:0009967=IDA, GO:0042982=IMP, GO:0006898=IDA, GO:0048260=IMP, GO:0009898=IDA, GO:0001784=IDA, GO:0055037=IDA, GO:0005769=IDA, GO:0090003=IMP, GO:0050750=IPI} amyloid precursor protein metabolic process, cholesterol homeostasis, cholesterol metabolic process, positive regulation of cholesterol metabolic process, positive regulation of receptor-mediated endocytosis, positive regulation of signal transduction, receptor internalization, receptor-mediated endocytosis, receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport, regulation of establishment of protein localization to plasma membrane, regulation of protein binding, transport AP-1 adaptor complex, AP-2 adaptor complex, axon, basal plasma membrane, cytosol, early endosome, internal side of plasma membrane, neurofilament, recycling endosome AP-2 adaptor complex binding, beta-amyloid binding, clathrin adaptor activity, clathrin binding, low-density lipoprotein particle receptor binding, phosphatidylinositol-4,5-bisphosphate binding, phosphotyrosine binding, protein binding, receptor signaling complex scaffold activity, signaling adaptor activity Human LDOC1 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0008285=PMID:10403563, GO:0005634=GO_REF:0000039} O95751 Protein LDOC1 protein 20130415 {GO:0005515=IPI, GO:0008285=TAS, GO:0005634=IEA} negative regulation of cell proliferation nucleus protein binding Human UniProtKB:Q9H9D4 LDOC1L null null {} null null null null {} null null null LEAP2 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039, GO:0042742=GO_REF:0000037} Q969E1 Liver-expressed antimicrobial peptide 2 protein 20130413 {GO:0005576=IEA, GO:0042742=IEA} defense response to bacterium extracellular region Human UniProtKB-SubCell:SL-0243 LECT1 PINC UniProtKB {GO:0030948=GO_REF:0000019, GO:0001501=PMID:10103018, GO:0051216=GO_REF:0000037, GO:0001937=GO_REF:0000019, GO:0001886=GO_REF:0000019, GO:0016525=PMID:16980969, GO:0005576=GO_REF:0000039, GO:0006029=PMID:10103018, GO:0016021=GO_REF:0000037, GO:0012505=GO_REF:0000039} O75829 Leukocyte cell-derived chemotaxin 1 protein 20030904 {GO:0030948=IEA, GO:0001501=TAS, GO:0051216=IEA, GO:0001937=IEA, GO:0001886=IEA, GO:0016525=IDA, GO:0005576=IEA, GO:0006029=TAS, GO:0016021=IEA, GO:0012505=IEA} cartilage development, endothelial cell morphogenesis, negative regulation of angiogenesis, negative regulation of endothelial cell proliferation, negative regulation of vascular endothelial growth factor receptor signaling pathway, proteoglycan metabolic process, skeletal system development endomembrane system, extracellular region, integral to membrane Human LECT2 PINC UniProtKB {GO:0001501=PMID:9545637, GO:0005737=GO_REF:0000039, GO:0006935=GO_REF:0000037, GO:0030178=GO_REF:0000019, GO:0005615=PMID:9266841} O14960 Leukocyte cell-derived chemotaxin-2 protein 20030904 {GO:0001501=TAS, GO:0005737=IEA, GO:0006935=IEA, GO:0030178=IEA, GO:0005615=TAS} chemotaxis, negative regulation of Wnt receptor signaling pathway, skeletal system development cytoplasm, extracellular space Human LEF1 BHF-UCL UniProtKB {GO:0005515=PMID:23001182, GO:0003700=PMID:11751639, GO:0060710=GO_REF:0000033, GO:0006366=PMID:23001182, GO:0008013=PMID:9488439, GO:0044212=PMID:16344550, GO:0030307=PMID:20360943, GO:0032714=PMID:18445004, GO:0003705=GO_REF:0000033, GO:0001756=GO_REF:0000033, GO:0046632=GO_REF:0000033, GO:0032713=PMID:18445004, GO:0001755=GO_REF:0000033, GO:0030879=GO_REF:0000033, GO:0021861=GO_REF:0000033, GO:0048747=GO_REF:0000033, GO:0032993=PMID:10825188, GO:0050909=GO_REF:0000019, GO:0048069=GO_REF:0000033, GO:0016202=GO_REF:0000033, GO:0071353=PMID:18579517, GO:0071864=PMID:17063141, GO:0016055=PMID:10644691, GO:0071866=PMID:17063141, GO:0043027=PMID:20360943, GO:0021542=GO_REF:0000033, GO:0022407=GO_REF:0000019, GO:0000977=PMID:23001182, GO:0030335=PMID:20018240, GO:0060033=GO_REF:0000019, GO:0045295=PMID:14661054, GO:0033153=GO_REF:0000019, GO:0008301=GO_REF:0000024, GO:0030331=PMID:18794125, GO:0021879=GO_REF:0000033, GO:0030509=GO_REF:0000033, GO:0000122=GO_REF:0000019, GO:0021873=GO_REF:0000033, GO:0043923=PMID:7657162, GO:0035326=PMID:7657162, GO:0001649=PMID:20128911, GO:0043392=PMID:18445004, GO:0045843=GO_REF:0000019, GO:0043966=PMID:20363964, GO:0061153=GO_REF:0000033, GO:0071345=PMID:23001182, GO:0043967=PMID:20363964, GO:0007420=GO_REF:0000033, GO:0070742=PMID:18445004, GO:0048341=GO_REF:0000033, GO:0043586=GO_REF:0000019, GO:0045893=PMID:10644691, GO:0045892=PMID:20363964, GO:0070016=PMID:12408825, GO:0008134=GO_REF:0000019, GO:0008284=PMID:19351848, GO:0010718=PMID:20018240, GO:0048699=GO_REF:0000033, GO:0030284=PMID:18794125, GO:0021943=GO_REF:0000033, GO:0002040=GO_REF:0000033, GO:0005634=PMID:23001182, GO:0001837=GO_REF:0000024, GO:0030326=GO_REF:0000033, GO:0042393=PMID:20363964, GO:0005737=PMID:23001182, GO:0042100=GO_REF:0000033, GO:0045944=PMID:23001182, GO:0030854=PMID:23001182, GO:0060021=GO_REF:0000024, GO:0042475=GO_REF:0000019, GO:0030223=PMID:17063141, GO:0043154=PMID:20360943, GO:0090090=PMID:19402906, GO:0060070=PMID:20123964, GO:0022008=GO_REF:0000033, GO:0005667=PMID:23001182, GO:0043066=PMID:20360943, GO:0001569=GO_REF:0000033, GO:0060561=GO_REF:0000033, GO:0006917=GO_REF:0000033, GO:0001228=PMID:23001182, GO:0021854=GO_REF:0000033, GO:0003677=GO_REF:0000024, GO:0010628=PMID:16344550, GO:0043565=PMID:10825188, GO:0071899=PMID:18794125, GO:0060325=GO_REF:0000033, GO:0045063=GO_REF:0000024, GO:0060326=PMID:19576624, GO:0032696=PMID:18445004, GO:0003682=GO_REF:0000033, GO:0071895=GO_REF:0000033} Q9UJU2 Lymphoid enhancer-binding factor 1 protein 20121119 {GO:0005515=IPI, GO:0003700=IDA, GO:0060710=IBA, GO:0006366=IDA, GO:0008013=IDA, GO:0044212=IDA, GO:0030307=IMP, GO:0032714=IDA, GO:0003705=IBA, GO:0001756=IBA, GO:0046632=IBA, GO:0032713=IDA, GO:0001755=IBA, GO:0030879=IBA, GO:0021861=IBA, GO:0048747=IBA, GO:0032993=IDA, GO:0050909=IEA, GO:0048069=IBA, GO:0016202=IBA, GO:0071353=IDA, GO:0071864=IMP, GO:0016055=IDA, GO:0071866=IMP, GO:0043027=IMP, GO:0021542=IBA, GO:0022407=IEA, GO:0000977=IDA, GO:0030335=IMP, GO:0060033=IEA, GO:0045295=IPI, GO:0033153=IEA, GO:0008301=ISS, GO:0030331=IDA, GO:0021879=IBA, GO:0030509=IBA, GO:0000122=IEA, GO:0021873=IBA, GO:0043923=IDA, GO:0035326=IDA, GO:0001649=IEP, GO:0043392=IDA, GO:0045843=IEA, GO:0043966=IMP, GO:0061153=IBA, GO:0071345=IMP, GO:0043967=IMP, GO:0007420=IBA, GO:0070742=IPI, GO:0048341=IBA, GO:0043586=IEA, GO:0045893=IDA, GO:0045892=IMP, GO:0070016=IPI, GO:0008134=IEA, GO:0008284=IDA, GO:0010718=IMP, GO:0048699=IBA, GO:0030284=IDA, GO:0021943=IBA, GO:0002040=IBA, GO:0005634=IDA, GO:0001837=ISS, GO:0030326=IBA, GO:0042393=IPI, GO:0005737=IDA, GO:0042100=IBA, GO:0045944=IMP, GO:0030854=IMP, GO:0060021=ISS, GO:0042475=IEA, GO:0030223=IMP, GO:0043154=IMP, GO:0090090=IMP, GO:0060070=IDA, GO:0022008=IBA, GO:0005667=IDA, GO:0043066=IMP, GO:0001569=IBA, GO:0060561=IBA, GO:0006917=IBA, GO:0001228=IMP, GO:0021854=IBA, GO:0003677=ISS, GO:0010628=IDA, GO:0043565=IDA, GO:0071899=IDA, GO:0060325=IBA, GO:0045063=ISS, GO:0060326=IDA, GO:0032696=IDA, GO:0003682=IBA, GO:0071895=IBA} B cell proliferation, BMP signaling pathway, T cell receptor V(D)J recombination, T-helper 1 cell differentiation, Wnt receptor signaling pathway, alpha-beta T cell differentiation, anatomical structure regression, apoptotic process involved in morphogenesis, brain development, canonical Wnt receptor signaling pathway, cell chemotaxis, cellular response to cytokine stimulus, cellular response to interleukin-4, chorio-allantoic fusion, dentate gyrus development, embryonic limb morphogenesis, epithelial to mesenchymal transition, eye pigmentation, face morphogenesis, forebrain neuroblast division, forebrain neuron differentiation, forebrain radial glial cell differentiation, formation of radial glial scaffolds, generation of neurons, histone H3 acetylation, histone H4 acetylation, hypothalamus development, induction of apoptosis, mammary gland development, muscle fiber development, negative regulation of DNA binding, negative regulation of apoptotic process, negative regulation of apoptotic process in bone marrow, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of estrogen receptor binding, negative regulation of interleukin-13 production, negative regulation of interleukin-4 production, negative regulation of interleukin-5 production, negative regulation of striated muscle tissue development, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, neural crest cell migration, neurogenesis, neutrophil differentiation, odontoblast differentiation, odontogenesis of dentin-containing tooth, osteoblast differentiation, palate development, paraxial mesoderm formation, patterning of blood vessels, positive regulation by host of viral transcription, positive regulation of cell growth, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of cell proliferation in bone marrow, positive regulation of epithelial to mesenchymal transition, positive regulation of gene expression, positive regulation of granulocyte differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of cell-cell adhesion, regulation of striated muscle tissue development, sensory perception of taste, somitogenesis, sprouting angiogenesis, tongue development, trachea gland development, transcription from RNA polymerase II promoter cytoplasm, nucleus, protein-DNA complex, transcription factor complex C2H2 zinc finger domain binding, DNA binding, DNA binding, bending, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, RNA polymerase II regulatory region sequence-specific DNA binding, RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, armadillo repeat domain binding, beta-catenin binding, chromatin binding, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, enhancer binding, estrogen receptor activity, estrogen receptor binding, gamma-catenin binding, histone binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding Human LEFTY2 Reactome UniProtKB {GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0030168=Reactome:REACT_798, GO:0016049=GO_REF:0000002, GO:0031093=Reactome:REACT_21351, GO:0005576=Reactome:REACT_21351, GO:0007179=PMID:9153275, GO:0007275=GO_REF:0000037, GO:0008083=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037, GO:0005160=GO_REF:0000002} O00292 Left-right determination factor 2 protein 20130213 {GO:0007596=TAS, GO:0002576=TAS, GO:0030168=TAS, GO:0016049=IEA, GO:0031093=TAS, GO:0005576=TAS, GO:0007179=TAS, GO:0007275=IEA, GO:0008083=IEA, GO:0005615=IEA, GO:0005125=IEA, GO:0005160=IEA} blood coagulation, cell growth, multicellular organismal development, platelet activation, platelet degranulation, transforming growth factor beta receptor signaling pathway extracellular region, extracellular space, platelet alpha granule lumen cytokine activity, growth factor activity, transforming growth factor beta receptor binding Human LEMD2 HPA UniProtKB {GO:0043409=GO_REF:0000019, GO:0031965=GO_REF:0000052, GO:0035914=PMID:19720741, GO:0005639=PMID:16339967} Q8NC56 LEM domain-containing protein 2 protein 20090616 {GO:0043409=IEA, GO:0031965=IDA, GO:0035914=IGI, GO:0005639=IDA} negative regulation of MAPK cascade, skeletal muscle cell differentiation integral to nuclear inner membrane, nuclear membrane Human LEMD3 MGI UniProtKB {GO:0030514=PMID:15647271, GO:0005515=PMID:15647271, GO:0016020=PMID:10671519, GO:0000166=GO_REF:0000002, GO:0051726=GO_REF:0000019, GO:0005637=PMID:15647271, GO:0032926=PMID:15647271, GO:0016021=PMID:10671519, GO:0035914=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0030512=PMID:15647271, GO:0005639=GO_REF:0000002} Q9Y2U8 Inner nuclear membrane protein Man1 protein 20060131 {GO:0030514=IDA, GO:0005515=IPI, GO:0016020=TAS, GO:0000166=IEA, GO:0051726=IEA, GO:0005637=IDA, GO:0032926=IDA, GO:0016021=IDA, GO:0035914=IEA, GO:0003677=IEA, GO:0030512=IDA, GO:0005639=IEA} negative regulation of BMP signaling pathway, negative regulation of activin receptor signaling pathway, negative regulation of transforming growth factor beta receptor signaling pathway, regulation of cell cycle, skeletal muscle cell differentiation integral to membrane, integral to nuclear inner membrane, membrane, nuclear inner membrane DNA binding, nucleotide binding, protein binding Human LENG1 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q96BZ8 Leukocyte receptor cluster member 1 protein 20061106 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human LENG8 UniProtKB UniProtKB {GO:0005515=PMID:16239144} Q96PV6 Leukocyte receptor cluster member 8 protein 20090723 {GO:0005515=IPI} protein binding Human UniProtKB:P60896 LENG9 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0016070=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003824=GO_REF:0000002} Q96B70 Leukocyte receptor cluster member 9 protein 20130413 {GO:0005622=IEA, GO:0016070=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003824=IEA} RNA metabolic process intracellular catalytic activity, nucleic acid binding, zinc ion binding Human InterPro:IPR000571 LEO1 HPA UniProtKB {GO:0005515=PMID:20178742, GO:0006378=PMID:21329879, GO:0033523=PMID:16307923, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037, GO:0001711=GO_REF:0000024, GO:0045638=PMID:20541477, GO:0019827=PMID:19345177, GO:0045944=PMID:20178742, GO:0032968=PMID:20178742, GO:0016593=PMID:20178742, GO:0016055=GO_REF:0000037, GO:0010390=PMID:16307923, GO:0031442=PMID:21329879} Q8WVC0 RNA polymerase-associated protein LEO1 protein 20110516 {GO:0005515=IPI, GO:0006378=IMP, GO:0033523=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0006351=IEA, GO:0001711=ISS, GO:0045638=IDA, GO:0019827=IDA, GO:0045944=IDA, GO:0032968=IDA, GO:0016593=IDA, GO:0016055=IEA, GO:0010390=IDA, GO:0031442=IMP} Wnt receptor signaling pathway, endodermal cell fate commitment, histone H2B ubiquitination, histone monoubiquitination, mRNA polyadenylation, negative regulation of myeloid cell differentiation, positive regulation of mRNA 3'-end processing, positive regulation of transcription elongation from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter, stem cell maintenance, transcription, DNA-dependent Cdc73/Paf1 complex, nucleolus, nucleus protein binding NOT Human LEP Reactome UniProtKB {GO:2000491=GO_REF:0000019, GO:0033686=GO_REF:0000019, GO:0071298=GO_REF:0000019, GO:0071300=GO_REF:0000019, GO:0030300=GO_REF:0000019, GO:0001819=GO_REF:0000019, GO:0005615=GO_REF:0000024, GO:0002021=GO_REF:0000019, GO:0050901=GO_REF:0000019, GO:0043270=GO_REF:0000019, GO:0033197=GO_REF:0000019, GO:2000486=GO_REF:0000019, GO:0032868=GO_REF:0000019, GO:0060587=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:0001542=GO_REF:0000019, GO:0046881=GO_REF:0000019, GO:0001890=PMID:17957153, GO:0000122=GO_REF:0000019, GO:0005179=GO_REF:0000019, GO:0048639=PMID:17957153, GO:0033210=GO_REF:0000019, GO:0007623=GO_REF:0000019, GO:0042445=GO_REF:0000019, GO:0030073=GO_REF:0000019, GO:0008083=GO_REF:0000019, GO:0035630=GO_REF:0000019, GO:0008343=GO_REF:0000024, GO:0007260=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0032099=GO_REF:0000024, GO:0050810=GO_REF:0000019, GO:0051428=GO_REF:0000019, GO:0009062=GO_REF:0000019, GO:0045639=GO_REF:0000019, GO:0045906=GO_REF:0000019, GO:0006006=GO_REF:0000019, GO:0008206=GO_REF:0000019, GO:2000366=GO_REF:0000019, GO:0008203=GO_REF:0000019, GO:0070093=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0042517=GO_REF:0000019, GO:0021954=GO_REF:0000019, GO:0046628=GO_REF:0000019, GO:0005576=Reactome:REACT_27275, GO:0006111=GO_REF:0000019, GO:0006112=GO_REF:0000019, GO:0050796=GO_REF:0000019, GO:0006114=GO_REF:0000019, GO:0008217=GO_REF:0000019, GO:0061037=GO_REF:0000019, GO:0042755=GO_REF:0000019, GO:0043410=GO_REF:0000019, GO:0060612=GO_REF:0000019} P41159 Leptin protein 20090324 {GO:2000491=IEA, GO:0033686=IEA, GO:0071298=IEA, GO:0071300=IEA, GO:0030300=IEA, GO:0001819=IEA, GO:0005615=ISS, GO:0002021=IEA, GO:0050901=IEA, GO:0043270=IEA, GO:0033197=IEA, GO:2000486=IEA, GO:0032868=IEA, GO:0060587=IEA, GO:0007565=IEA, GO:0001542=IEA, GO:0046881=IEA, GO:0001890=IDA, GO:0000122=IEA, GO:0005179=IEA, GO:0048639=IDA, GO:0033210=IEA, GO:0007623=IEA, GO:0042445=IEA, GO:0030073=IEA, GO:0008083=IEA, GO:0035630=IEA, GO:0008343=ISS, GO:0007260=IEA, GO:0008284=IEA, GO:0032099=ISS, GO:0050810=IEA, GO:0051428=IEA, GO:0009062=IEA, GO:0045639=IEA, GO:0045906=IEA, GO:0006006=IEA, GO:0008206=IEA, GO:2000366=IEA, GO:0008203=IEA, GO:0070093=IEA, GO:0001666=IEA, GO:0043066=IEA, GO:0042517=IEA, GO:0021954=IEA, GO:0046628=IEA, GO:0005576=TAS, GO:0006111=IEA, GO:0006112=IEA, GO:0050796=IEA, GO:0006114=IEA, GO:0008217=IEA, GO:0061037=IEA, GO:0042755=IEA, GO:0043410=IEA, GO:0060612=IEA} adipose tissue development, adult feeding behavior, bile acid metabolic process, bone mineralization involved in bone maturation, cellular response to L-ascorbic acid, cellular response to retinoic acid, central nervous system neuron development, cholesterol metabolic process, circadian rhythm, eating behavior, energy reserve metabolic process, fatty acid catabolic process, female pregnancy, glucose metabolic process, glycerol biosynthetic process, hormone metabolic process, insulin secretion, leptin-mediated signaling pathway, leukocyte tethering or rolling, negative regulation of apoptotic process, negative regulation of appetite, negative regulation of cartilage development, negative regulation of glucagon secretion, negative regulation of glutamine transport, negative regulation of transcription from RNA polymerase II promoter, negative regulation of vasoconstriction, ovulation from ovarian follicle, placenta development, positive regulation of MAPK cascade, positive regulation of STAT protein import into nucleus, positive regulation of cell proliferation, positive regulation of cytokine production, positive regulation of developmental growth, positive regulation of follicle-stimulating hormone secretion, positive regulation of hepatic stellate cell activation, positive regulation of insulin receptor signaling pathway, positive regulation of ion transport, positive regulation of luteinizing hormone secretion, positive regulation of myeloid cell differentiation, positive regulation of tyrosine phosphorylation of Stat3 protein, regulation of blood pressure, regulation of gluconeogenesis, regulation of insulin secretion, regulation of intestinal cholesterol absorption, regulation of lipoprotein lipid oxidation, regulation of steroid biosynthetic process, response to dietary excess, response to hypoxia, response to insulin stimulus, response to vitamin E, tyrosine phosphorylation of STAT protein extracellular region, extracellular space growth factor activity, hormone activity, peptide hormone receptor binding Human LEPR IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0006112=PMID:9537324, GO:0004896=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0051346=GO_REF:0000019, GO:0007275=PMID:9537324, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0007166=PMID:9537324, GO:0004888=PMID:9537324, GO:0008203=GO_REF:0000019} P48357 Leptin receptor protein 20130415 {GO:0005515=IPI, GO:0006112=TAS, GO:0004896=IEA, GO:0005886=IEA, GO:0051346=IEA, GO:0007275=TAS, GO:0005576=IEA, GO:0016021=IEA, GO:0007166=TAS, GO:0004888=TAS, GO:0008203=IEA} cell surface receptor signaling pathway, cholesterol metabolic process, energy reserve metabolic process, multicellular organismal development, negative regulation of hydrolase activity extracellular region, integral to membrane, plasma membrane cytokine receptor activity, protein binding, transmembrane signaling receptor activity Human UniProtKB:P62993 LEPRE1 Reactome UniProtKB {GO:0031418=GO_REF:0000037, GO:0008285=PMID:10951563, GO:0005506=GO_REF:0000002, GO:0005578=GO_REF:0000039, GO:0005634=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0030278=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0019797=GO_REF:0000003, GO:0030199=GO_REF:0000019, GO:0016049=GO_REF:0000019, GO:0005788=Reactome:REACT_121152, GO:0016702=GO_REF:0000037} Q32P28 Prolyl 3-hydroxylase 1 protein 20120416 {GO:0031418=IEA, GO:0008285=NAS, GO:0005506=IEA, GO:0005578=IEA, GO:0005634=IEA, GO:0005575=ND, GO:0003674=ND, GO:0030278=IEA, GO:0030198=TAS, GO:0019797=IEA, GO:0030199=IEA, GO:0016049=IEA, GO:0005788=TAS, GO:0016702=IEA} cell growth, collagen fibril organization, extracellular matrix organization, negative regulation of cell proliferation, regulation of ossification cellular_component, endoplasmic reticulum lumen, nucleus, proteinaceous extracellular matrix L-ascorbic acid binding, iron ion binding, molecular_function, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, procollagen-proline 3-dioxygenase activity Human LEPREL1 Reactome UniProtKB {GO:0008285=PMID:19436308, GO:0005794=PMID:15063763, GO:0031418=GO_REF:0000037, GO:0005506=GO_REF:0000002, GO:0030198=Reactome:REACT_118779, GO:0005783=PMID:15063763, GO:0016706=GO_REF:0000002, GO:0005788=Reactome:REACT_121152, GO:0016702=GO_REF:0000037, GO:0005604=GO_REF:0000024} Q8IVL5 Prolyl 3-hydroxylase 2 protein 20130301 {GO:0008285=IDA, GO:0005794=IDA, GO:0031418=IEA, GO:0005506=IEA, GO:0030198=TAS, GO:0005783=IDA, GO:0016706=IEA, GO:0005788=TAS, GO:0016702=IEA, GO:0005604=ISS} extracellular matrix organization, negative regulation of cell proliferation Golgi apparatus, basement membrane, endoplasmic reticulum, endoplasmic reticulum lumen L-ascorbic acid binding, iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Human LEPREL2 Reactome UniProtKB {GO:0008285=PMID:19436308, GO:0031418=GO_REF:0000037, GO:0005506=GO_REF:0000002, GO:0030198=Reactome:REACT_118779, GO:0019797=GO_REF:0000003, GO:0016706=GO_REF:0000002, GO:0005788=Reactome:REACT_121152, GO:0016702=GO_REF:0000037} Q8IVL6 Prolyl 3-hydroxylase 3 protein 20130301 {GO:0008285=IDA, GO:0031418=IEA, GO:0005506=IEA, GO:0030198=TAS, GO:0019797=IEA, GO:0016706=IEA, GO:0005788=TAS, GO:0016702=IEA} extracellular matrix organization, negative regulation of cell proliferation endoplasmic reticulum lumen L-ascorbic acid binding, iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, procollagen-proline 3-dioxygenase activity Human LEPREL4 PINC UniProtKB {GO:0000794=PMID:8862517, GO:0000795=PMID:8862517, GO:0005730=GO_REF:0000039, GO:0007130=PMID:8862517} Q92791 Synaptonemal complex protein SC65 protein 20030904 {GO:0000794=TAS, GO:0000795=TAS, GO:0005730=IEA, GO:0007130=TAS} synaptonemal complex assembly condensed nuclear chromosome, nucleolus, synaptonemal complex Human LEPROT UniProtKB UniProtKB {GO:0060400=PMID:19907080, GO:0005794=PMID:18042720, GO:0000139=GO_REF:0000039, GO:0005102=PMID:18042720, GO:0016021=GO_REF:0000037, GO:0046426=PMID:18042720, GO:0010008=GO_REF:0000039, GO:2000009=PMID:18042720, GO:0005768=PMID:18042720} O15243 Leptin receptor gene-related protein protein 20111129 {GO:0060400=IDA, GO:0005794=IDA, GO:0000139=IEA, GO:0005102=IDA, GO:0016021=IEA, GO:0046426=IDA, GO:0010008=IEA, GO:2000009=IDA, GO:0005768=IDA} negative regulation of JAK-STAT cascade, negative regulation of growth hormone receptor signaling pathway, negative regulation of protein localization to cell surface Golgi apparatus, Golgi membrane, endosome, endosome membrane, integral to membrane receptor binding Human LEPROTL1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} O95214 Leptin receptor overlapping transcript-like 1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 LETM1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005515=PMID:18628306, GO:0005509=GO_REF:0000002, GO:0005743=PMID:18628306, GO:0016021=GO_REF:0000037, GO:0042407=PMID:18628306} O95202 LETM1 and EF-hand domain-containing protein 1, mitochondrial protein 20081203 {GO:0005739=IDA, GO:0005515=IPI, GO:0005509=IEA, GO:0005743=IDA, GO:0016021=IEA, GO:0042407=IMP} cristae formation integral to membrane, mitochondrial inner membrane, mitochondrion calcium ion binding, protein binding Human LETM2 UniProtKB UniProtKB {GO:0005743=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q2VYF4 LETM1 domain-containing protein LETM2, mitochondrial protein 20130413 {GO:0005743=IEA, GO:0016021=IEA} integral to membrane, mitochondrial inner membrane Human UniProtKB-SubCell:SL-0168 LETMD1 IntAct UniProtKB {GO:0005515=PMID:16762630, GO:0005739=GO_REF:0000019, GO:0005741=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q6P1Q0 LETM1 domain-containing protein 1 protein 20130415 {GO:0005515=IPI, GO:0005739=IEA, GO:0005741=IEA, GO:0016021=IEA} integral to membrane, mitochondrial outer membrane, mitochondrion protein binding Human UniProtKB:Q00765 LFNG Reactome UniProtKB {GO:0045747=GO_REF:0000019, GO:0003674=GO_REF:0000015, GO:0033829=GO_REF:0000003, GO:0007386=GO_REF:0000019, GO:0001541=GO_REF:0000019, GO:0030173=GO_REF:0000002, GO:0007219=Reactome:REACT_299, GO:0009887=PMID:10341080, GO:0005576=PMID:10341080, GO:0007143=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0032092=GO_REF:0000019} Q8NES3 Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe protein 20130301 {GO:0045747=IEA, GO:0003674=ND, GO:0033829=IEA, GO:0007386=IEA, GO:0001541=IEA, GO:0030173=IEA, GO:0007219=TAS, GO:0009887=NAS, GO:0005576=NAS, GO:0007143=IEA, GO:0046872=IEA, GO:0032092=IEA} Notch signaling pathway, compartment pattern specification, female meiosis, organ morphogenesis, ovarian follicle development, positive regulation of Notch signaling pathway, positive regulation of protein binding extracellular region, integral to Golgi membrane O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity, metal ion binding, molecular_function Human LGALS1 GOC UniProtKB {GO:0034120=GO_REF:0000019, GO:0031295=GO_REF:0000019, GO:0010812=GO_REF:0000019, GO:0016936=GO_REF:0000002, GO:0005634=GO_REF:0000019, GO:0048678=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0005622=GO_REF:0000054, GO:0005737=PMID:16130169, GO:0001948=GO_REF:0000019, GO:0045445=GO_REF:0000019, GO:0004871=PMID:12761501, GO:0071333=GO_REF:0000019, GO:0043123=PMID:12761501, GO:0030395=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0005578=GO_REF:0000039, GO:0006915=PMID:1713454, GO:0042981=PMID:16130169, GO:0033555=GO_REF:0000019, GO:0031012=PMID:22261194, GO:0007165=PMID:12761501, GO:0071407=GO_REF:0000019, GO:0043236=GO_REF:0000019, GO:0010977=GO_REF:0000019, GO:0002317=GO_REF:0000019} P09382 Galectin-1 protein 20130413 {GO:0034120=IEA, GO:0031295=IEA, GO:0010812=IEA, GO:0016936=IEA, GO:0005634=IEA, GO:0048678=IEA, GO:0042803=IEA, GO:0005622=IDA, GO:0005737=TAS, GO:0001948=IEA, GO:0045445=IEA, GO:0004871=IMP, GO:0071333=IEA, GO:0043123=IMP, GO:0030395=IEA, GO:0009986=IEA, GO:0042493=IEA, GO:0005578=IEA, GO:0006915=TAS, GO:0042981=TAS, GO:0033555=IEA, GO:0031012=ISS, GO:0007165=IMP, GO:0071407=IEA, GO:0043236=IEA, GO:0010977=IEA, GO:0002317=IEA} T cell costimulation, apoptotic process, cellular response to glucose stimulus, cellular response to organic cyclic compound, multicellular organismal response to stress, myoblast differentiation, negative regulation of cell-substrate adhesion, negative regulation of neuron projection development, plasma cell differentiation, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of erythrocyte aggregation, regulation of apoptotic process, response to axon injury, response to drug, signal transduction cell surface, cytoplasm, extracellular matrix, intracellular, nucleus, proteinaceous extracellular matrix galactoside binding, glycoprotein binding, lactose binding, laminin binding, protein homodimerization activity, signal transducer activity Human LGALS12 MGI UniProtKB {GO:0005739=GO_REF:0000019, GO:0030246=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0097193=PMID:11435439, GO:0030395=PMID:11435439} Q96DT0 Galectin-12 protein 20040223 {GO:0005739=IEA, GO:0030246=IEA, GO:0005634=IEA, GO:0097193=IDA, GO:0030395=IDA} intrinsic apoptotic signaling pathway mitochondrion, nucleus carbohydrate binding, lactose binding Human LGALS13 PINC UniProtKB {GO:0016042=GO_REF:0000037, GO:0004091=GO_REF:0000037, GO:0004622=GO_REF:0000003, GO:0030246=GO_REF:0000002, GO:0006644=PMID:10527825} Q9UHV8 Galactoside-binding soluble lectin 13 protein 20030904 {GO:0016042=IEA, GO:0004091=IEA, GO:0004622=IEA, GO:0030246=IEA, GO:0006644=TAS} lipid catabolic process, phospholipid metabolic process carbohydrate binding, carboxylesterase activity, lysophospholipase activity Human LGALS2 ENSEMBL UniProtKB {GO:0030246=GO_REF:0000002, GO:0016936=GO_REF:0000019} P05162 Galectin-2 protein 20130413 {GO:0030246=IEA, GO:0016936=IEA} carbohydrate binding, galactoside binding Human Ensembl:ENSRNOP00000011750 LGALS3 Reactome UniProtKB {GO:0006397=GO_REF:0000037, GO:0008380=GO_REF:0000037, GO:0005515=PMID:19016746, GO:0005886=PMID:9162064, GO:0005578=GO_REF:0000019, GO:0005743=PMID:19016746, GO:0005634=PMID:14961764, GO:0030154=GO_REF:0000037, GO:0001501=GO_REF:0000019, GO:0005737=PMID:14961764, GO:0019863=GO_REF:0000037, GO:0030198=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0030246=GO_REF:0000002, GO:0005681=GO_REF:0000037} P17931 Galectin-3 protein 20130301 {GO:0006397=IEA, GO:0008380=IEA, GO:0005515=IPI, GO:0005886=TAS, GO:0005578=IEA, GO:0005743=IDA, GO:0005634=IDA, GO:0030154=IEA, GO:0001501=IEA, GO:0005737=IDA, GO:0019863=IEA, GO:0030198=IEA, GO:0045087=TAS, GO:0030246=IEA, GO:0005681=IEA} RNA splicing, cell differentiation, extracellular matrix organization, innate immune response, mRNA processing, skeletal system development cytoplasm, mitochondrial inner membrane, nucleus, plasma membrane, proteinaceous extracellular matrix, spliceosomal complex IgE binding, carbohydrate binding, protein binding Human LGALS3BP PINC UniProtKB {GO:0007165=PMID:8390986, GO:0006968=PMID:8034587, GO:0016020=GO_REF:0000002, GO:0005578=GO_REF:0000039, GO:0007155=GO_REF:0000037, GO:0005615=PMID:8390986, GO:0005044=GO_REF:0000002} Q08380 Galectin-3-binding protein protein 20030904 {GO:0007165=TAS, GO:0006968=TAS, GO:0016020=IEA, GO:0005578=IEA, GO:0007155=IEA, GO:0005615=TAS, GO:0005044=IEA} cell adhesion, cellular defense response, signal transduction extracellular space, membrane, proteinaceous extracellular matrix scavenger receptor activity Human LGALS4 PINC UniProtKB {GO:0005886=PMID:9162064, GO:0030246=GO_REF:0000002, GO:0007155=PMID:9162064, GO:0005829=PMID:9162064} P56470 Galectin-4 protein 20030904 {GO:0005886=TAS, GO:0030246=IEA, GO:0007155=TAS, GO:0005829=TAS} cell adhesion cytosol, plasma membrane carbohydrate binding Human LGALS7 PINC UniProtKB {GO:0005737=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0030246=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0005615=PMID:7534301, GO:0007157=PMID:7534301} P47929 Galectin-7 protein 20031119 {GO:0005737=IEA, GO:0006915=IEA, GO:0030246=IEA, GO:0005634=IEA, GO:0005615=TAS, GO:0007157=TAS} apoptotic process, heterophilic cell-cell adhesion cytoplasm, extracellular space, nucleus carbohydrate binding Human LGALS7B null null {} null null null null {} null null null LGALS8 ENSEMBL UniProtKB {GO:0005737=GO_REF:0000039, GO:0031295=GO_REF:0000019, GO:0002317=GO_REF:0000019, GO:0030246=GO_REF:0000019, GO:0005615=PMID:8692978} Q5T3P9 Galectin-8 protein 20130413 {GO:0005737=IEA, GO:0031295=IEA, GO:0002317=IEA, GO:0030246=IEA, GO:0005615=TAS} T cell costimulation, plasma cell differentiation cytoplasm, extracellular space carbohydrate binding Human Ensembl:ENSMUSP00000115094 LGALS9 InterPro UniProtKB {GO:0007165=PMID:12761501, GO:0005737=GO_REF:0000039, GO:0005534=PMID:9045665, GO:0030246=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0004871=PMID:12761501, GO:0043123=PMID:12761501} Q8WYQ7 Lectin, galactoside-binding, soluble, 9 (Galectin 9), isoform CRA_b protein 20130413 {GO:0007165=IMP, GO:0005737=IEA, GO:0005534=TAS, GO:0030246=IEA, GO:0005576=IEA, GO:0004871=IMP, GO:0043123=IMP} positive regulation of I-kappaB kinase/NF-kappaB cascade, signal transduction cytoplasm, extracellular region carbohydrate binding, galactose binding, signal transducer activity Human InterPro:IPR001079 LGALSL LIFEdb UniProtKB {GO:0005622=GO_REF:0000054, GO:0030246=GO_REF:0000002} Q3ZCW2 Galectin-related protein protein 20100607 {GO:0005622=IDA, GO:0030246=IEA} intracellular carbohydrate binding Human LGI1 PINC UniProtKB {GO:0005515=PMID:20463223, GO:0030054=GO_REF:0000037, GO:0008283=PMID:9879993, GO:0007411=PMID:20463223, GO:0030307=PMID:20463223, GO:0050806=GO_REF:0000024, GO:0005102=PMID:20463223, GO:0045202=GO_REF:0000039, GO:0005576=GO_REF:0000039, GO:0051260=GO_REF:0000019, GO:0031175=PMID:20463223, GO:0007399=PMID:9879993} O95970 Leucine-rich glioma-inactivated protein 1 protein 20030904 {GO:0005515=IPI, GO:0030054=IEA, GO:0008283=TAS, GO:0007411=IMP, GO:0030307=IMP, GO:0050806=ISS, GO:0005102=IPI, GO:0045202=IEA, GO:0005576=IEA, GO:0051260=IEA, GO:0031175=IMP, GO:0007399=TAS} axon guidance, cell proliferation, nervous system development, neuron projection development, positive regulation of cell growth, positive regulation of synaptic transmission, protein homooligomerization cell junction, extracellular region, synapse protein binding, receptor binding Human LGI4 ENSEMBL UniProtKB {GO:0008344=GO_REF:0000019, GO:0042551=GO_REF:0000019, GO:0022011=GO_REF:0000019, GO:0005615=GO_REF:0000019} Q8N135 Leucine-rich repeat LGI family member 4 protein 20130413 {GO:0008344=IEA, GO:0042551=IEA, GO:0022011=IEA, GO:0005615=IEA} adult locomotory behavior, myelination in peripheral nervous system, neuron maturation extracellular space Human Ensembl:ENSMUSP00000041579 LGMN Reactome UniProtKB {GO:0005770=GO_REF:0000019, GO:0042359=Reactome:REACT_13523, GO:0045177=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0002224=Reactome:REACT_6966, GO:0004197=PMID:9065484, GO:0019886=Reactome:REACT_121399, GO:0043524=PMID:18374643, GO:0040015=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0006508=PMID:9065484, GO:0001101=GO_REF:0000019, GO:0008233=PMID:136644, GO:0008202=Reactome:REACT_11057, GO:0043202=Reactome:REACT_121251} Q99538 Legumain protein 20130301 {GO:0005770=IEA, GO:0042359=TAS, GO:0045177=IEA, GO:0044281=TAS, GO:0002224=TAS, GO:0004197=ISS, GO:0019886=TAS, GO:0043524=IGI, GO:0040015=IEA, GO:0045087=TAS, GO:0006508=ISS, GO:0001101=IEA, GO:0008233=IDA, GO:0008202=TAS, GO:0043202=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, innate immune response, negative regulation of multicellular organism growth, negative regulation of neuron apoptotic process, proteolysis, response to acid, small molecule metabolic process, steroid metabolic process, toll-like receptor signaling pathway, vitamin D metabolic process apical part of cell, late endosome, lysosomal lumen cysteine-type endopeptidase activity, peptidase activity Human LGR4 PINC UniProtKB {GO:0072202=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0004930=PMID:10894923, GO:0072282=GO_REF:0000019, GO:0072224=GO_REF:0000019, GO:0050673=GO_REF:0000019, GO:0016500=GO_REF:0000002, GO:0030539=GO_REF:0000019, GO:0061290=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0045893=GO_REF:0000019, GO:0045892=GO_REF:0000019, GO:0090190=GO_REF:0000019} Q9BXB1 Leucine-rich repeat-containing G-protein coupled receptor 4 protein 20050308 {GO:0072202=IEA, GO:0005886=IEA, GO:0004930=TAS, GO:0072282=IEA, GO:0072224=IEA, GO:0050673=IEA, GO:0016500=IEA, GO:0030539=IEA, GO:0061290=IEA, GO:0016021=IEA, GO:0045893=IEA, GO:0045892=IEA, GO:0090190=IEA} canonical Wnt receptor signaling pathway involved in metanephric kidney development, cell differentiation involved in metanephros development, epithelial cell proliferation, male genitalia development, metanephric glomerulus development, metanephric nephron tubule morphogenesis, negative regulation of transcription, DNA-dependent, positive regulation of branching involved in ureteric bud morphogenesis, positive regulation of transcription, DNA-dependent integral to membrane, plasma membrane G-protein coupled receptor activity, protein-hormone receptor activity Human LGR6 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0016500=GO_REF:0000002} Q9HBX8 Leucine-rich repeat-containing G-protein coupled receptor 6 protein 20130413 {GO:0005886=IEA, GO:0016021=IEA, GO:0016500=IEA} integral to membrane, plasma membrane protein-hormone receptor activity Human UniProtKB-SubCell:SL-0039 LGSN InterPro UniProtKB {GO:0004356=GO_REF:0000002, GO:0006542=GO_REF:0000002} Q5TDP6 Lengsin protein 20130413 {GO:0004356=IEA, GO:0006542=IEA} glutamine biosynthetic process glutamate-ammonia ligase activity Human InterPro:IPR008147 LHB BHF-UCL UniProtKB {GO:0007165=PMID:10484773, GO:0006701=PMID:14557487, GO:0016486=Reactome:REACT_15452, GO:0005179=GO_REF:0000037, GO:0007267=PMID:10484773, GO:0005102=PMID:10484773, GO:0005576=Reactome:REACT_22268, GO:0044267=Reactome:REACT_17015, GO:0008584=PMID:6785294} P01229 Lutropin subunit beta protein 20080820 {GO:0007165=TAS, GO:0006701=TAS, GO:0016486=TAS, GO:0005179=IEA, GO:0007267=TAS, GO:0005102=TAS, GO:0005576=TAS, GO:0044267=TAS, GO:0008584=TAS} cell-cell signaling, cellular protein metabolic process, male gonad development, peptide hormone processing, progesterone biosynthetic process, signal transduction extracellular region hormone activity, receptor binding Human LHCGR BHF-UCL UniProtKB {GO:0060065=GO_REF:0000019, GO:0038106=GO_REF:0000024, GO:0046544=GO_REF:0000019, GO:0005886=Reactome:REACT_22268, GO:0007200=GO_REF:0000024, GO:0004964=GO_REF:0000002, GO:0007283=GO_REF:0000019, GO:0007190=GO_REF:0000024, GO:0030539=PMID:9626653, GO:0001541=GO_REF:0000019, GO:0071371=GO_REF:0000024, GO:0007186=PMID:9626653, GO:0005887=GO_REF:0000024, GO:0007187=PMID:7719343, GO:0072520=GO_REF:0000019, GO:0043950=GO_REF:0000024, GO:0032962=GO_REF:0000024, GO:0035472=GO_REF:0000024, GO:0016021=GO_REF:0000002, GO:0090030=GO_REF:0000019, GO:0008584=PMID:7719343, GO:0005768=PMID:10617611} P22888 Lutropin-choriogonadotropic hormone receptor protein 20120308 {GO:0060065=IEA, GO:0038106=ISS, GO:0046544=IEA, GO:0005886=TAS, GO:0007200=ISS, GO:0004964=IEA, GO:0007283=IEA, GO:0007190=ISS, GO:0030539=TAS, GO:0001541=IEA, GO:0071371=ISS, GO:0007186=TAS, GO:0005887=ISS, GO:0007187=TAS, GO:0072520=IEA, GO:0043950=ISS, GO:0032962=ISS, GO:0035472=ISS, GO:0016021=IEA, GO:0090030=IEA, GO:0008584=TAS, GO:0005768=TAS} G-protein coupled receptor signaling pathway, G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, activation of adenylate cyclase activity, cellular response to gonadotropin stimulus, development of secondary male sexual characteristics, male genitalia development, male gonad development, ovarian follicle development, phospholipase C-activating G-protein coupled receptor signaling pathway, positive regulation of cAMP-mediated signaling, positive regulation of inositol trisphosphate biosynthetic process, regulation of steroid hormone biosynthetic process, seminiferous tubule development, spermatogenesis, uterus development endosome, integral to membrane, integral to plasma membrane, plasma membrane choriogonadotropin hormone binding, choriogonadotropin hormone receptor activity, luteinizing hormone receptor activity Human UniProtKB:P30730 LHFPL2 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q6ZUX7 Lipoma HMGIC fusion partner-like 2 protein protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 LHPP HPA UniProtKB {GO:0008969=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0000287=GO_REF:0000024, GO:0006470=GO_REF:0000024, GO:0016787=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0004427=PMID:12801912, GO:0005634=GO_REF:0000052, GO:0006796=PMID:12801912, GO:0042803=PMID:12801912, GO:0005829=PMID:16430861} Q9H008 Phospholysine phosphohistidine inorganic pyrophosphate phosphatase protein 20101115 {GO:0008969=ISS, GO:0005737=IDA, GO:0000287=ISS, GO:0006470=ISS, GO:0016787=IEA, GO:0005730=IDA, GO:0004427=IDA, GO:0005634=IDA, GO:0006796=IDA, GO:0042803=IPI, GO:0005829=IDA} phosphate-containing compound metabolic process, protein dephosphorylation cytoplasm, cytosol, nucleolus, nucleus hydrolase activity, inorganic diphosphatase activity, magnesium ion binding, phosphohistidine phosphatase activity, protein homodimerization activity Human LHX1 PINC UniProtKB {GO:0010468=GO_REF:0000024, GO:0007389=GO_REF:0000024, GO:0001657=GO_REF:0000024, GO:0001658=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0006366=GO_REF:0000024, GO:0001655=GO_REF:0000024, GO:0048793=GO_REF:0000019, GO:0048703=GO_REF:0000024, GO:0009791=GO_REF:0000024, GO:0009653=GO_REF:0000024, GO:0072077=GO_REF:0000024, GO:0009880=GO_REF:0000024, GO:0072278=GO_REF:0000019, GO:0035846=GO_REF:0000024, GO:0035847=GO_REF:0000024, GO:0048646=GO_REF:0000024, GO:0072177=GO_REF:0000019, GO:0072178=GO_REF:0000024, GO:0009887=PMID:7700351, GO:0035849=GO_REF:0000019, GO:0001705=GO_REF:0000024, GO:0001706=GO_REF:0000024, GO:0003714=GO_REF:0000024, GO:0021937=GO_REF:0000024, GO:0021549=GO_REF:0000024, GO:0010842=GO_REF:0000024, GO:0072049=GO_REF:0000024, GO:0001702=GO_REF:0000024, GO:0021871=GO_REF:0000024, GO:0043234=GO_REF:0000024, GO:2000768=GO_REF:0000024, GO:0008045=GO_REF:0000024, GO:0072284=GO_REF:0000019, GO:0072283=GO_REF:0000019, GO:0035852=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0072050=GO_REF:0000024, GO:0045893=GO_REF:0000024, GO:0045892=GO_REF:0000024, GO:0060429=GO_REF:0000024, GO:0060065=GO_REF:0000024, GO:0060067=GO_REF:0000024, GO:0060066=GO_REF:0000024, GO:0060068=GO_REF:0000024, GO:0007267=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0009953=GO_REF:0000024, GO:0009952=GO_REF:0000024, GO:0021517=GO_REF:0000019, GO:0021537=GO_REF:0000019, GO:0032525=GO_REF:0000019, GO:0009948=GO_REF:0000024, GO:0021702=GO_REF:0000024, GO:0040019=GO_REF:0000024, GO:0090190=GO_REF:0000024, GO:2000744=GO_REF:0000024, GO:0090009=GO_REF:0000024, GO:0001822=GO_REF:0000024, GO:2000543=GO_REF:0000024, GO:0035502=GO_REF:0000019, GO:0060059=GO_REF:0000024, GO:0072224=GO_REF:0000019, GO:0021527=GO_REF:0000024, GO:0044344=GO_REF:0000019, GO:0007399=PMID:9212161, GO:0043565=GO_REF:0000002, GO:0061205=GO_REF:0000024, GO:0001071=GO_REF:0000024, GO:0060322=GO_REF:0000024, GO:0001764=GO_REF:0000024} P48742 LIM/homeobox protein Lhx1 protein 20031120 {GO:0010468=ISS, GO:0007389=ISS, GO:0001657=ISS, GO:0001658=IEA, GO:0003700=IEA, GO:0006366=ISS, GO:0001655=ISS, GO:0048793=IEA, GO:0048703=ISS, GO:0009791=ISS, GO:0009653=ISS, GO:0072077=ISS, GO:0009880=ISS, GO:0072278=IEA, GO:0035846=ISS, GO:0035847=ISS, GO:0048646=ISS, GO:0072177=IEA, GO:0072178=ISS, GO:0009887=TAS, GO:0035849=IEA, GO:0001705=ISS, GO:0001706=ISS, GO:0003714=ISS, GO:0021937=ISS, GO:0021549=ISS, GO:0010842=ISS, GO:0072049=ISS, GO:0001702=ISS, GO:0021871=ISS, GO:0043234=ISS, GO:2000768=ISS, GO:0008045=ISS, GO:0072284=IEA, GO:0072283=IEA, GO:0035852=IEA, GO:0008270=IEA, GO:0072050=ISS, GO:0045893=ISS, GO:0045892=ISS, GO:0060429=ISS, GO:0060065=ISS, GO:0060067=ISS, GO:0060066=ISS, GO:0060068=ISS, GO:0007267=ISS, GO:0005634=ISS, GO:0009953=ISS, GO:0009952=ISS, GO:0021517=IEA, GO:0021537=IEA, GO:0032525=IEA, GO:0009948=ISS, GO:0021702=ISS, GO:0040019=ISS, GO:0090190=ISS, GO:2000744=ISS, GO:0090009=ISS, GO:0001822=ISS, GO:2000543=ISS, GO:0035502=IEA, GO:0060059=ISS, GO:0072224=IEA, GO:0021527=ISS, GO:0044344=IEA, GO:0007399=TAS, GO:0043565=IEA, GO:0061205=ISS, GO:0001071=ISS, GO:0060322=ISS, GO:0001764=ISS} S-shaped body morphogenesis, anatomical structure formation involved in morphogenesis, anatomical structure morphogenesis, anterior/posterior axis specification, anterior/posterior pattern specification, branching involved in ureteric bud morphogenesis, cell-cell signaling, cellular response to fibroblast growth factor stimulus, cerebellar Purkinje cell differentiation, cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation, cerebellum development, cervix development, comma-shaped body morphogenesis, dorsal/ventral pattern formation, ectoderm formation, embryonic pattern specification, embryonic retina morphogenesis in camera-type eye, embryonic viscerocranium morphogenesis, endoderm formation, epithelium development, forebrain regionalization, gastrulation with mouth forming second, head development, horizontal cell localization, kidney development, mesonephric duct development, metanephric S-shaped body morphogenesis, metanephric comma-shaped body morphogenesis, metanephric glomerulus development, metanephric part of ureteric bud development, metanephric renal vesicle morphogenesis, motor neuron axon guidance, negative regulation of transcription, DNA-dependent, nephric duct elongation, nephric duct morphogenesis, nervous system development, neuron migration, organ morphogenesis, oviduct development, oviduct epithelium development, paramesonephric duct development, pattern specification process, positive regulation of anterior head development, positive regulation of branching involved in ureteric bud morphogenesis, positive regulation of embryonic development, positive regulation of gastrulation, positive regulation of nephron tubule epithelial cell differentiation, positive regulation of transcription, DNA-dependent, post-embryonic development, primitive streak formation, pronephros development, regulation of gene expression, renal vesicle morphogenesis, retina layer formation, somite rostral/caudal axis specification, spinal cord association neuron differentiation, telencephalon development, transcription from RNA polymerase II promoter, ureteric bud development, urogenital system development, uterine epithelium development, uterus development, vagina development, ventral spinal cord development nucleus, protein complex nucleic acid binding transcription factor activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity, zinc ion binding Human LHX2 UniProtKB UniProtKB {GO:0000988=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0001843=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0009953=GO_REF:0000019, GO:0021978=GO_REF:0000019, GO:2000678=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0007498=GO_REF:0000019, GO:0045893=GO_REF:0000024} P50458 LIM/homeobox protein Lhx2 protein 20110420 {GO:0000988=IEA, GO:0003700=IEA, GO:0001843=IEA, GO:0005634=IEA, GO:0009953=IEA, GO:0021978=IEA, GO:2000678=IEA, GO:0006351=IEA, GO:0043565=IEA, GO:0007411=IEA, GO:0045944=IEA, GO:0008270=IEA, GO:0007498=IEA, GO:0045893=ISS} axon guidance, dorsal/ventral pattern formation, mesoderm development, negative regulation of transcription regulatory region DNA binding, neural tube closure, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, telencephalon regionalization, transcription, DNA-dependent nucleus protein binding transcription factor activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB:Q9Z0S2 LHX3 PINC UniProtKB {GO:0000988=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0048839=PMID:18407919, GO:0043066=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0021521=GO_REF:0000019, GO:0021520=GO_REF:0000019, GO:0021983=GO_REF:0000019, GO:0005634=PMID:10598593, GO:0001890=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0021527=GO_REF:0000019, GO:0021526=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0008045=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0009887=PMID:10598593, GO:0008270=GO_REF:0000002, GO:0045893=GO_REF:0000024} Q9UBR4 LIM/homeobox protein Lhx3 protein 20031120 {GO:0000988=IEA, GO:0005667=IEA, GO:0048839=IEP, GO:0043066=IEA, GO:0003700=IEA, GO:0021521=IEA, GO:0021520=IEA, GO:0021983=IEA, GO:0005634=TAS, GO:0001890=IEA, GO:0006351=IEA, GO:0021527=IEA, GO:0021526=IEA, GO:0043565=IEA, GO:0008045=IEA, GO:0045944=IEA, GO:0009887=TAS, GO:0008270=IEA, GO:0045893=ISS} inner ear development, medial motor column neuron differentiation, motor neuron axon guidance, negative regulation of apoptotic process, organ morphogenesis, pituitary gland development, placenta development, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, spinal cord association neuron differentiation, spinal cord motor neuron cell fate specification, transcription, DNA-dependent, ventral spinal cord interneuron specification nucleus, transcription factor complex protein binding transcription factor activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human LHX4 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0043066=GO_REF:0000019, GO:0008045=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0009887=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0001890=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0021526=GO_REF:0000019} Q969G2 LIM/homeobox protein Lhx4 protein 20130413 {GO:0043565=IEA, GO:0043066=IEA, GO:0008045=IEA, GO:0003700=IEA, GO:0009887=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0001890=IEA, GO:0006351=IEA, GO:0021526=IEA} medial motor column neuron differentiation, motor neuron axon guidance, negative regulation of apoptotic process, organ morphogenesis, placenta development, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB-SubCell:SL-0191 LHX9 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0008585=GO_REF:0000019, GO:0008045=GO_REF:0000024, GO:0035262=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0008283=GO_REF:0000019, GO:0003714=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0045892=GO_REF:0000024, GO:0008584=GO_REF:0000019} Q9NQ69 LIM/homeobox protein Lhx9 protein 20110504 {GO:0043565=IEA, GO:0008585=IEA, GO:0008045=ISS, GO:0035262=IEA, GO:0003700=IEA, GO:0008283=IEA, GO:0003714=ISS, GO:0005634=IEA, GO:0008270=IEA, GO:0045892=ISS, GO:0008584=IEA} cell proliferation, female gonad development, gonad morphogenesis, male gonad development, motor neuron axon guidance, negative regulation of transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity, zinc ion binding Human UniProtKB:Q90881 LIF BHF-UCL UniProtKB {GO:0060426=GO_REF:0000019, GO:0008284=PMID:8999038, GO:0042503=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0050731=PMID:7508917, GO:0033141=PMID:20624457, GO:1900182=PMID:22783022, GO:1901676=PMID:22783022, GO:0005615=PMID:12643274, GO:0046888=PMID:7867561, GO:0048644=GO_REF:0000019, GO:0046697=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0006955=GO_REF:0000002, GO:0033138=PMID:7508917, GO:0048666=GO_REF:0000019, GO:0045944=PMID:22783022, GO:0072307=PMID:20624457, GO:0070373=GO_REF:0000019, GO:0005146=PMID:8999038, GO:0048286=GO_REF:0000019, GO:0007566=GO_REF:0000019, GO:0042517=PMID:20624457, GO:0060708=GO_REF:0000019, GO:0060707=GO_REF:0000019, GO:0042511=PMID:20624457, GO:0005102=PMID:8999038, GO:0007275=PMID:3143918, GO:0045651=PMID:7957045, GO:0005125=PMID:7957045, GO:0072108=PMID:20624457, GO:0048861=PMID:12643274, GO:0048711=GO_REF:0000019, GO:0001974=GO_REF:0000019, GO:0019827=GO_REF:0000019, GO:0060463=GO_REF:0000019, GO:0001135=PMID:22783022, GO:0043410=PMID:7508917, GO:0045835=GO_REF:0000019, GO:0008083=PMID:12643274} P15018 Leukemia inhibitory factor protein 20121122 {GO:0060426=IEA, GO:0008284=IDA, GO:0042503=IEA, GO:0008285=IEA, GO:0050731=IDA, GO:0033141=IDA, GO:1900182=IDA, GO:1901676=IDA, GO:0005615=IC, GO:0046888=IDA, GO:0048644=IEA, GO:0046697=IEA, GO:0005737=IDA, GO:0006955=IEA, GO:0033138=IDA, GO:0048666=IEA, GO:0045944=IDA, GO:0072307=IDA, GO:0070373=IEA, GO:0005146=IPI, GO:0048286=IEA, GO:0007566=IEA, GO:0042517=IDA, GO:0060708=IEA, GO:0060707=IEA, GO:0042511=IDA, GO:0005102=IPI, GO:0007275=TAS, GO:0045651=IDA, GO:0005125=IDA, GO:0072108=IDA, GO:0048861=IDA, GO:0048711=IEA, GO:0001974=IEA, GO:0019827=IEA, GO:0060463=IEA, GO:0001135=IDA, GO:0043410=IDA, GO:0045835=IEA, GO:0008083=IDA} blood vessel remodeling, decidualization, embryo implantation, immune response, leukemia inhibitory factor signaling pathway, lung alveolus development, lung lobe morphogenesis, lung vasculature development, multicellular organismal development, muscle organ morphogenesis, negative regulation of ERK1 and ERK2 cascade, negative regulation of cell proliferation, negative regulation of hormone secretion, negative regulation of meiosis, neuron development, positive regulation of MAPK cascade, positive regulation of astrocyte differentiation, positive regulation of cell proliferation, positive regulation of histone H3-K27 acetylation, positive regulation of macrophage differentiation, positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis, positive regulation of peptidyl-serine phosphorylation, positive regulation of peptidyl-serine phosphorylation of STAT protein, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of protein localization to nucleus, positive regulation of transcription from RNA polymerase II promoter, positive regulation of tyrosine phosphorylation of Stat1 protein, positive regulation of tyrosine phosphorylation of Stat3 protein, regulation of metanephric nephron tubule epithelial cell differentiation, spongiotrophoblast differentiation, stem cell maintenance, trophoblast giant cell differentiation, tyrosine phosphorylation of Stat3 protein cytoplasm, extracellular space RNA polymerase II transcription factor recruiting transcription factor activity, cytokine activity, growth factor activity, leukemia inhibitory factor receptor binding, receptor binding Human LIFR GOC UniProtKB {GO:0008284=PMID:8999038, GO:0004924=PMID:8999038, GO:0004923=PMID:12643274, GO:0019221=PMID:7957045, GO:0005576=GO_REF:0000039, GO:0070120=PMID:12643274, GO:0038165=PMID:8999038, GO:0005127=PMID:12707266, GO:0048861=PMID:12643274, GO:0019838=PMID:8999038, GO:0005887=PMID:1915266, GO:0004897=PMID:12643274, GO:0034097=PMID:8999038, GO:0007166=PMID:1915266} P42702 Leukemia inhibitory factor receptor protein 20130413 {GO:0008284=IDA, GO:0004924=IDA, GO:0004923=IDA, GO:0019221=IDA, GO:0005576=IEA, GO:0070120=IDA, GO:0038165=IDA, GO:0005127=IPI, GO:0048861=IDA, GO:0019838=IPI, GO:0005887=TAS, GO:0004897=IDA, GO:0034097=IDA, GO:0007166=TAS} cell surface receptor signaling pathway, ciliary neurotrophic factor-mediated signaling pathway, cytokine-mediated signaling pathway, leukemia inhibitory factor signaling pathway, oncostatin-M-mediated signaling pathway, positive regulation of cell proliferation, response to cytokine stimulus extracellular region, integral to plasma membrane ciliary neurotrophic factor receptor activity, ciliary neurotrophic factor receptor binding, growth factor binding, leukemia inhibitory factor receptor activity, oncostatin-M receptor activity Human LIG1 UniProtKB UniProtKB {GO:0042542=GO_REF:0000019, GO:0003909=PMID:9809069, GO:0005634=GO_REF:0000033, GO:0006303=GO_REF:0000019, GO:0009653=PMID:8696349, GO:0046872=GO_REF:0000037, GO:0006302=Reactome:REACT_2054, GO:0006273=GO_REF:0000033, GO:0005739=GO_REF:0000033, GO:0000084=Reactome:REACT_899, GO:0006271=Reactome:REACT_932, GO:0000723=Reactome:REACT_7970, GO:0000724=Reactome:REACT_1874, GO:0000722=Reactome:REACT_8027, GO:0006297=Reactome:REACT_1998, GO:0033151=PMID:9809069, GO:0005694=GO_REF:0000033, GO:0006310=GO_REF:0000038, GO:0003910=GO_REF:0000003, GO:0006259=PMID:2204063, GO:0005524=GO_REF:0000038, GO:0003677=GO_REF:0000002, GO:0006260=GO_REF:0000038, GO:0006281=Reactome:REACT_216, GO:0051103=GO_REF:0000002, GO:0006283=Reactome:REACT_1628, GO:0006284=Reactome:REACT_1104, GO:0005654=Reactome:REACT_7994, GO:0006289=Reactome:REACT_1826, GO:0000278=Reactome:REACT_152, GO:0032201=Reactome:REACT_7961, GO:0051301=GO_REF:0000037} Q2TB12 DNA ligase protein 20130413 {GO:0042542=IEA, GO:0003909=IDA, GO:0005634=IBA, GO:0006303=IEA, GO:0009653=TAS, GO:0046872=IEA, GO:0006302=TAS, GO:0006273=IBA, GO:0005739=IBA, GO:0000084=TAS, GO:0006271=TAS, GO:0000723=TAS, GO:0000724=TAS, GO:0000722=TAS, GO:0006297=TAS, GO:0033151=IDA, GO:0005694=IBA, GO:0006310=IEA, GO:0003910=IEA, GO:0006259=TAS, GO:0005524=IEA, GO:0003677=IEA, GO:0006260=IEA, GO:0006281=TAS, GO:0051103=IEA, GO:0006283=TAS, GO:0006284=TAS, GO:0005654=TAS, GO:0006289=TAS, GO:0000278=TAS, GO:0032201=TAS, GO:0051301=IEA} DNA ligation involved in DNA repair, DNA metabolic process, DNA recombination, DNA repair, DNA replication, DNA strand elongation involved in DNA replication, S phase of mitotic cell cycle, V(D)J recombination, anatomical structure morphogenesis, base-excision repair, cell division, double-strand break repair, double-strand break repair via homologous recombination, double-strand break repair via nonhomologous end joining, lagging strand elongation, mitotic cell cycle, nucleotide-excision repair, nucleotide-excision repair, DNA gap filling, response to hydrogen peroxide, telomere maintenance, telomere maintenance via recombination, telomere maintenance via semi-conservative replication, transcription-coupled nucleotide-excision repair chromosome, mitochondrion, nucleoplasm, nucleus ATP binding, DNA binding, DNA ligase (ATP) activity, DNA ligase activity, metal ion binding Human EC:6.5.1.1 LIG3 HPA UniProtKB {GO:0005515=PMID:15744309, GO:0033151=PMID:9809069, GO:0000795=GO_REF:0000019, GO:0005694=GO_REF:0000033, GO:0003909=PMID:9809069, GO:0005634=GO_REF:0000052, GO:0006310=GO_REF:0000002, GO:0007283=PMID:7565692, GO:0003910=GO_REF:0000033, GO:0006303=GO_REF:0000019, GO:0003677=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0006273=GO_REF:0000033, GO:0005739=GO_REF:0000033, GO:0006281=Reactome:REACT_216, GO:0051103=GO_REF:0000002, GO:0006284=Reactome:REACT_1104, GO:0043504=GO_REF:0000019, GO:0005654=Reactome:REACT_1659, GO:0008270=GO_REF:0000002, GO:0006289=GO_REF:0000033, GO:0045910=GO_REF:0000019, GO:0007131=PMID:7565692, GO:0051301=GO_REF:0000037} P49916 DNA ligase 3 protein 20080205 {GO:0005515=IPI, GO:0033151=IDA, GO:0000795=IEA, GO:0005694=IBA, GO:0003909=IDA, GO:0005634=IDA, GO:0006310=IEA, GO:0007283=TAS, GO:0003910=IBA, GO:0006303=IEA, GO:0003677=IEA, GO:0005524=IEA, GO:0006273=IBA, GO:0005739=IBA, GO:0006281=TAS, GO:0051103=IEA, GO:0006284=TAS, GO:0043504=IEA, GO:0005654=TAS, GO:0008270=IEA, GO:0006289=IBA, GO:0045910=IEA, GO:0007131=TAS, GO:0051301=IEA} DNA ligation involved in DNA repair, DNA recombination, DNA repair, V(D)J recombination, base-excision repair, cell division, double-strand break repair via nonhomologous end joining, lagging strand elongation, mitochondrial DNA repair, negative regulation of DNA recombination, nucleotide-excision repair, reciprocal meiotic recombination, spermatogenesis chromosome, mitochondrion, nucleoplasm, nucleus, synaptonemal complex ATP binding, DNA binding, DNA ligase (ATP) activity, DNA ligase activity, protein binding, zinc ion binding Human LIG4 HPA UniProtKB {GO:0005515=PMID:16439205, GO:0000793=PMID:12589063, GO:0016874=PMID:9242410, GO:0003909=Reactome:REACT_115886, GO:0051402=GO_REF:0000024, GO:0043524=GO_REF:0000024, GO:0006297=PMID:12517771, GO:0002328=GO_REF:0000024, GO:0010332=GO_REF:0000024, GO:0071285=GO_REF:0000019, GO:0033077=GO_REF:0000024, GO:0033151=PMID:9809069, GO:0033152=GO_REF:0000019, GO:0033153=GO_REF:0000024, GO:0045190=GO_REF:0000024, GO:0003910=PMID:8798671, GO:0007417=GO_REF:0000024, GO:0001701=GO_REF:0000024, GO:0007049=GO_REF:0000037, GO:0006281=Reactome:REACT_216, GO:0051103=GO_REF:0000024, GO:0051102=GO_REF:0000024, GO:0005654=Reactome:REACT_9073, GO:0005925=GO_REF:0000052, GO:0075713=Reactome:REACT_6918, GO:0051301=GO_REF:0000037, GO:0000012=PMID:8798671, GO:0022415=Reactome:REACT_6266, GO:0051276=GO_REF:0000024, GO:0010165=PMID:9809069, GO:0005886=GO_REF:0000052, GO:0008283=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0048146=GO_REF:0000024, GO:0006303=Reactome:REACT_1022, GO:0046872=GO_REF:0000037, GO:0006302=Reactome:REACT_2054, GO:0006273=GO_REF:0000033, GO:0005737=GO_REF:0000052, GO:0050769=GO_REF:0000024, GO:0016032=Reactome:REACT_6256, GO:0005958=PMID:15194694, GO:0035019=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0008022=PMID:12589063, GO:0005524=GO_REF:0000019, GO:0003677=PMID:8798671, GO:0032807=PMID:9809069, GO:0070419=PMID:20383123, GO:0006266=PMID:12517771} P49917 DNA ligase 4 protein 20101115 {GO:0005515=IPI, GO:0000793=IDA, GO:0016874=IDA, GO:0003909=TAS, GO:0051402=ISS, GO:0043524=ISS, GO:0006297=IDA, GO:0002328=ISS, GO:0010332=ISS, GO:0071285=IEA, GO:0033077=ISS, GO:0033151=IDA, GO:0033152=IEA, GO:0033153=ISS, GO:0045190=ISS, GO:0003910=IDA, GO:0007417=ISS, GO:0001701=ISS, GO:0007049=IEA, GO:0006281=TAS, GO:0051103=ISS, GO:0051102=ISS, GO:0005654=TAS, GO:0005925=IDA, GO:0075713=TAS, GO:0051301=IEA, GO:0000012=IDA, GO:0022415=TAS, GO:0051276=ISS, GO:0010165=IMP, GO:0005886=IDA, GO:0008283=ISS, GO:0005634=IDA, GO:0048146=ISS, GO:0006303=TAS, GO:0046872=IEA, GO:0006302=TAS, GO:0006273=IBA, GO:0005737=IDA, GO:0050769=ISS, GO:0016032=TAS, GO:0005958=IDA, GO:0035019=ISS, GO:0005730=IDA, GO:0008022=IPI, GO:0005524=IEA, GO:0003677=IDA, GO:0032807=IMP, GO:0070419=IDA, GO:0006266=IDA} DNA ligation, DNA ligation involved in DNA recombination, DNA ligation involved in DNA repair, DNA repair, T cell differentiation in thymus, T cell receptor V(D)J recombination, V(D)J recombination, cell cycle, cell division, cell proliferation, cellular response to lithium ion, central nervous system development, chromosome organization, double-strand break repair, double-strand break repair via nonhomologous end joining, establishment of integrated proviral latency, immunoglobulin V(D)J recombination, in utero embryonic development, isotype switching, lagging strand elongation, negative regulation of neuron apoptotic process, neuron apoptotic process, nucleotide-excision repair, DNA gap filling, positive regulation of fibroblast proliferation, positive regulation of neurogenesis, pro-B cell differentiation, response to X-ray, response to gamma radiation, single strand break repair, somatic stem cell maintenance, viral reproduction, viral reproductive process DNA ligase IV complex, DNA-dependent protein kinase-DNA ligase 4 complex, condensed chromosome, cytoplasm, focal adhesion, nonhomologous end joining complex, nucleolus, nucleoplasm, nucleus, plasma membrane ATP binding, DNA binding, DNA ligase (ATP) activity, DNA ligase activity, ligase activity, metal ion binding, protein C-terminus binding, protein binding Human LILRA1 Reactome UniProtKB {GO:0005886=Reactome:REACT_11127, GO:0050776=Reactome:REACT_11152, GO:0006952=PMID:9548455, GO:0016021=GO_REF:0000037, GO:0003823=PMID:9548455, GO:0007166=PMID:9548455, GO:0004888=PMID:9548455} O75019 Leukocyte immunoglobulin-like receptor subfamily A member 1 protein 20130228 {GO:0005886=TAS, GO:0050776=TAS, GO:0006952=TAS, GO:0016021=IEA, GO:0003823=TAS, GO:0007166=TAS, GO:0004888=TAS} cell surface receptor signaling pathway, defense response, regulation of immune response integral to membrane, plasma membrane antigen binding, transmembrane signaling receptor activity Human LILRA3 PINC UniProtKB {GO:0007165=PMID:9151699, GO:0005886=PMID:9151699, GO:0006952=PMID:9151699, GO:0004872=PMID:9151699, GO:0005576=GO_REF:0000039, GO:0003823=PMID:9151699} Q8N6C8 Leukocyte immunoglobulin-like receptor subfamily A member 3 protein 20050308 {GO:0007165=TAS, GO:0005886=TAS, GO:0006952=TAS, GO:0004872=TAS, GO:0005576=IEA, GO:0003823=TAS} defense response, signal transduction extracellular region, plasma membrane antigen binding, receptor activity Human LILRB1 BHF-UCL UniProtKB {GO:0046636=PMID:21213105, GO:0042288=PMID:19124746, GO:0005886=Reactome:REACT_11127, GO:2001186=PMID:21213105, GO:0097028=PMID:18094328, GO:0042803=PMID:21213105, GO:0042130=PMID:15585844, GO:0031623=PMID:17869268, GO:0051607=PMID:15585844, GO:0002309=PMID:18094328, GO:0045944=PMID:18550825, GO:0045806=PMID:18094328, GO:0002774=PMID:9842885, GO:0032609=PMID:11907092, GO:0030109=PMID:11907092, GO:0042169=PMID:11907092, GO:2001199=PMID:18684926, GO:2001202=PMID:18094328, GO:0043065=PMID:21551166, GO:2001205=PMID:18802077, GO:2001193=PMID:21233315, GO:0009615=PMID:17869268, GO:0045786=PMID:21551166, GO:2000669=PMID:18094328, GO:0014063=PMID:11907092, GO:0032945=PMID:21551166, GO:0072643=PMID:15585844, GO:0007165=PMID:18802077, GO:0002767=PMID:18550825, GO:0071222=PMID:18094328, GO:0045919=PMID:18684926, GO:0035548=PMID:21213105, GO:0050776=Reactome:REACT_11152, GO:0001915=PMID:21213105, GO:0008157=PMID:18802077, GO:0016021=GO_REF:0000037, GO:2001189=PMID:18094328, GO:0009897=PMID:15585844, GO:0032393=PMID:21233315} Q8NHL6 Leukocyte immunoglobulin-like receptor subfamily B member 1 protein 20111125 {GO:0046636=IDA, GO:0042288=IPI, GO:0005886=TAS, GO:2001186=IDA, GO:0097028=IEP, GO:0042803=IPI, GO:0042130=IDA, GO:0031623=TAS, GO:0051607=IDA, GO:0002309=IDA, GO:0045944=NAS, GO:0045806=IDA, GO:0002774=IDA, GO:0032609=IDA, GO:0030109=IDA, GO:0042169=IDA, GO:2001199=IMP, GO:2001202=IDA, GO:0043065=IDA, GO:2001205=IDA, GO:2001193=IDA, GO:0009615=IDA, GO:0045786=IDA, GO:2000669=IDA, GO:0014063=IDA, GO:0032945=IDA, GO:0072643=IDA, GO:0007165=IDA, GO:0002767=NAS, GO:0071222=IEP, GO:0045919=IDA, GO:0035548=IDA, GO:0050776=TAS, GO:0001915=IDA, GO:0008157=IPI, GO:0016021=IEA, GO:2001189=IDA, GO:0009897=IDA, GO:0032393=IDA} Fc receptor mediated inhibitory signaling pathway, T cell proliferation involved in immune response, cellular response to lipopolysaccharide, defense response to virus, dendritic cell differentiation, immune response-inhibiting cell surface receptor signaling pathway, interferon-gamma production, interferon-gamma secretion, negative regulation of CD8-positive, alpha-beta T cell activation, negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell, negative regulation of T cell mediated cytotoxicity, negative regulation of T cell proliferation, negative regulation of alpha-beta T cell activation, negative regulation of cell cycle, negative regulation of dendritic cell apoptotic process, negative regulation of dendritic cell differentiation, negative regulation of endocytosis, negative regulation of interferon-beta secretion, negative regulation of mononuclear cell proliferation, negative regulation of osteoclast development, negative regulation of serotonin secretion, negative regulation of transforming growth factor-beta secretion, positive regulation of apoptotic process, positive regulation of cytolysis, positive regulation of gamma-delta T cell activation involved in immune response, positive regulation of transcription from RNA polymerase II promoter, receptor internalization, regulation of immune response, response to virus, signal transduction external side of plasma membrane, integral to membrane, plasma membrane HLA-B specific inhibitory MHC class I receptor activity, MHC class I protein binding, MHC class I receptor activity, SH2 domain binding, protein homodimerization activity, protein phosphatase 1 binding Human LILRB2 BHF-UCL UniProtKB {GO:0032755=PMID:18550825, GO:0005515=PMID:18802077, GO:0042288=PMID:19124746, GO:0043499=PMID:14971032, GO:0005886=Reactome:REACT_11127, GO:0007267=PMID:9382880, GO:0005615=PMID:14971032, GO:0042130=PMID:19124746, GO:0005737=PMID:19124746, GO:0006955=PMID:9079806, GO:0042102=PMID:14971032, GO:0002774=PMID:9842885, GO:0034113=PMID:19124746, GO:0004872=PMID:9382880, GO:0050839=PMID:19124746, GO:2001198=PMID:20008523, GO:0009986=PMID:14971032, GO:0002666=PMID:20008523, GO:0007165=PMID:20008523, GO:0006968=PMID:9382880, GO:0002767=PMID:20702625, GO:0071222=PMID:14971032, GO:0016020=PMID:9079806, GO:0002578=PMID:19124746, GO:0005887=PMID:14971032, GO:0050776=Reactome:REACT_11152, GO:0008157=PMID:9842885, GO:0032396=PMID:14971032, GO:0023029=PMID:20008523, GO:0007166=PMID:9079806} Q8N423 Leukocyte immunoglobulin-like receptor subfamily B member 2 protein 20111125 {GO:0032755=NAS, GO:0005515=IPI, GO:0042288=IPI, GO:0043499=IDA, GO:0005886=TAS, GO:0007267=TAS, GO:0005615=IDA, GO:0042130=IDA, GO:0005737=IDA, GO:0006955=TAS, GO:0042102=IDA, GO:0002774=IDA, GO:0034113=IDA, GO:0004872=TAS, GO:0050839=IPI, GO:2001198=IC, GO:0009986=IDA, GO:0002666=IMP, GO:0007165=IMP, GO:0006968=TAS, GO:0002767=IDA, GO:0071222=IMP, GO:0016020=TAS, GO:0002578=IDA, GO:0005887=IC, GO:0050776=TAS, GO:0008157=IPI, GO:0032396=IMP, GO:0023029=IPI, GO:0007166=TAS} Fc receptor mediated inhibitory signaling pathway, cell surface receptor signaling pathway, cell-cell signaling, cellular defense response, cellular response to lipopolysaccharide, heterotypic cell-cell adhesion, immune response, immune response-inhibiting cell surface receptor signaling pathway, negative regulation of T cell proliferation, negative regulation of antigen processing and presentation, positive regulation of T cell proliferation, positive regulation of T cell tolerance induction, positive regulation of interleukin-6 production, regulation of dendritic cell differentiation, regulation of immune response, signal transduction cell surface, cytoplasm, extracellular space, integral to plasma membrane, membrane, plasma membrane MHC class I protein binding, MHC class Ib protein binding, cell adhesion molecule binding, eukaryotic cell surface binding, inhibitory MHC class I receptor activity, protein binding, protein phosphatase 1 binding, receptor activity Human LILRB3 PINC UniProtKB {GO:0005515=PMID:18802077, GO:0005887=PMID:9278324, GO:0006952=PMID:9382880, GO:0004872=PMID:9382880, GO:0045671=PMID:18802077, GO:0007166=PMID:9382880, GO:0004888=PMID:9278324} O75022 Leukocyte immunoglobulin-like receptor subfamily B member 3 protein 20050308 {GO:0005515=IPI, GO:0005887=TAS, GO:0006952=TAS, GO:0004872=TAS, GO:0045671=IDA, GO:0007166=TAS, GO:0004888=TAS} cell surface receptor signaling pathway, defense response, negative regulation of osteoclast differentiation integral to plasma membrane protein binding, receptor activity, transmembrane signaling receptor activity Human LILRB4 PINC UniProtKB {GO:0005515=PMID:18802077, GO:0007165=PMID:9151699, GO:0005886=GO_REF:0000039, GO:0004872=PMID:9151699, GO:0045671=PMID:18802077, GO:0016021=GO_REF:0000037, GO:0003823=PMID:9151699} Q8NHJ6 Leukocyte immunoglobulin-like receptor subfamily B member 4 protein 20050308 {GO:0005515=IPI, GO:0007165=TAS, GO:0005886=IEA, GO:0004872=TAS, GO:0045671=IDA, GO:0016021=IEA, GO:0003823=TAS} negative regulation of osteoclast differentiation, signal transduction integral to membrane, plasma membrane antigen binding, protein binding, receptor activity Human LIM2 UniProtKB UniProtKB {GO:0005212=GO_REF:0000029, GO:0030054=PMID:2584203, GO:0005886=GO_REF:0000019, GO:0002088=GO_REF:0000019, GO:0007043=PMID:2584203, GO:0016021=GO_REF:0000037, GO:0031982=GO_REF:0000019} P55344 Lens fiber membrane intrinsic protein protein 20020606 {GO:0005212=NAS, GO:0030054=NAS, GO:0005886=IEA, GO:0002088=IEA, GO:0007043=NAS, GO:0016021=IEA, GO:0031982=IEA} cell-cell junction assembly, lens development in camera-type eye cell junction, integral to membrane, plasma membrane, vesicle structural constituent of eye lens Human LIMA1 HPA UniProtKB {GO:0003785=PMID:12566430, GO:0030835=PMID:12566430, GO:0001725=PMID:10618726, GO:0005737=GO_REF:0000052, GO:0051015=PMID:12566430, GO:0005886=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0015629=GO_REF:0000052, GO:0005925=PMID:10618726, GO:0051017=PMID:12566430, GO:0031529=PMID:12566430} Q9UHB6 LIM domain and actin-binding protein 1 protein 20120912 {GO:0003785=IDA, GO:0030835=IDA, GO:0001725=IDA, GO:0005737=IDA, GO:0051015=IDA, GO:0005886=IDA, GO:0008270=IEA, GO:0015629=IDA, GO:0005925=IDA, GO:0051017=IDA, GO:0031529=IDA} actin filament bundle assembly, negative regulation of actin filament depolymerization, ruffle organization actin cytoskeleton, cytoplasm, focal adhesion, plasma membrane, stress fiber actin filament binding, actin monomer binding, zinc ion binding Human LIMCH1 InterPro UniProtKB {GO:0031032=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0003779=GO_REF:0000002} Q9UPQ0 LIM and calponin homology domains-containing protein 1 protein 20130413 {GO:0031032=IEA, GO:0008270=IEA, GO:0003779=IEA} actomyosin structure organization actin binding, zinc ion binding Human InterPro:IPR001997 LIMD1 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0008360=PMID:21834987, GO:2000637=PMID:20616046, GO:0005634=PMID:18439753, GO:0016442=PMID:20616046, GO:0005737=PMID:18439753, GO:0005912=PMID:20303269, GO:0000932=PMID:20616046, GO:0007010=PMID:21834987, GO:0090090=GO_REF:0000024, GO:0001666=PMID:22286099, GO:0006355=PMID:10647888, GO:0033962=PMID:20616046, GO:0003714=GO_REF:0000024, GO:0007275=PMID:10647888, GO:0006351=GO_REF:0000037, GO:0016310=PMID:18439753, GO:0035331=PMID:20303269, GO:0007165=PMID:10647888, GO:0045668=GO_REF:0000024, GO:0002076=GO_REF:0000024, GO:0016477=PMID:21834987, GO:0035195=PMID:20616046, GO:0008270=GO_REF:0000002, GO:0005925=PMID:18439753, GO:0045892=PMID:22286099} Q9UGP4 LIM domain-containing protein 1 protein 20130415 {GO:0005515=IPI, GO:0008360=IMP, GO:2000637=IMP, GO:0005634=IDA, GO:0016442=IDA, GO:0005737=IDA, GO:0005912=IDA, GO:0000932=IDA, GO:0007010=IMP, GO:0090090=ISS, GO:0001666=IDA, GO:0006355=TAS, GO:0033962=IMP, GO:0003714=ISS, GO:0007275=TAS, GO:0006351=IEA, GO:0016310=IDA, GO:0035331=IDA, GO:0007165=TAS, GO:0045668=ISS, GO:0002076=ISS, GO:0016477=IMP, GO:0035195=IMP, GO:0008270=IEA, GO:0005925=IDA, GO:0045892=IMP} cell migration, cytoplasmic mRNA processing body assembly, cytoskeleton organization, gene silencing by miRNA, multicellular organismal development, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of hippo signaling cascade, negative regulation of osteoblast differentiation, negative regulation of transcription, DNA-dependent, osteoblast development, phosphorylation, positive regulation of gene silencing by miRNA, regulation of cell shape, regulation of transcription, DNA-dependent, response to hypoxia, signal transduction, transcription, DNA-dependent RNA-induced silencing complex, adherens junction, cytoplasm, cytoplasmic mRNA processing body, focal adhesion, nucleus protein binding, transcription corepressor activity, zinc ion binding Human UniProtKB:Q9Q2G4 LIMD2 InterPro UniProtKB {GO:0008270=GO_REF:0000002} Q9BT23 LIM domain-containing protein 2 protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR001781 LIME1 ENSEMBL UniProtKB {GO:0050853=GO_REF:0000019, GO:0042345=GO_REF:0000019, GO:0019815=GO_REF:0000019, GO:0050852=GO_REF:0000002, GO:0070851=GO_REF:0000019, GO:0043405=GO_REF:0000019, GO:0019901=GO_REF:0000019, GO:0006357=GO_REF:0000019, GO:0051279=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0014066=GO_REF:0000019} Q9H400 Lck-interacting transmembrane adapter 1 protein 20130413 {GO:0050853=IEA, GO:0042345=IEA, GO:0019815=IEA, GO:0050852=IEA, GO:0070851=IEA, GO:0043405=IEA, GO:0019901=IEA, GO:0006357=IEA, GO:0051279=IEA, GO:0016021=IEA, GO:0014066=IEA} B cell receptor signaling pathway, T cell receptor signaling pathway, regulation of MAP kinase activity, regulation of NF-kappaB import into nucleus, regulation of phosphatidylinositol 3-kinase cascade, regulation of release of sequestered calcium ion into cytosol, regulation of transcription from RNA polymerase II promoter B cell receptor complex, integral to membrane growth factor receptor binding, protein kinase binding Human Ensembl:ENSMUSP00000045010 LIMK1 HPA UniProtKB {GO:0005515=PMID:17512523, GO:0043005=GO_REF:0000024, GO:0030036=PMID:10428028, GO:0046982=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0045773=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0007266=PMID:10436159, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_160233, GO:0007399=PMID:8689688, GO:0007165=PMID:10436159, GO:0005737=GO_REF:0000052, GO:0004672=PMID:8537403, GO:0007411=Reactome:REACT_18266, GO:0004674=Reactome:REACT_19168, GO:0032233=PMID:17512523, GO:0031072=PMID:17512523, GO:0045087=Reactome:REACT_6802, GO:0051444=PMID:17512523, GO:0006468=PMID:17512523, GO:0008270=GO_REF:0000002, GO:0038096=Reactome:REACT_160123, GO:0005925=GO_REF:0000019} P53667 LIM domain kinase 1 protein 20101115 {GO:0005515=IPI, GO:0043005=ISS, GO:0030036=TAS, GO:0046982=IEA, GO:0005730=IDA, GO:0045773=ISS, GO:0005634=IDA, GO:0007266=TAS, GO:0005524=IEA, GO:0005829=TAS, GO:0007399=TAS, GO:0007165=TAS, GO:0005737=IDA, GO:0004672=NAS, GO:0007411=TAS, GO:0004674=TAS, GO:0032233=IDA, GO:0031072=IDA, GO:0045087=TAS, GO:0051444=IDA, GO:0006468=IDA, GO:0008270=IEA, GO:0038096=TAS, GO:0005925=IEA} Fc-gamma receptor signaling pathway involved in phagocytosis, Rho protein signal transduction, actin cytoskeleton organization, axon guidance, innate immune response, negative regulation of ubiquitin-protein ligase activity, nervous system development, positive regulation of actin filament bundle assembly, positive regulation of axon extension, protein phosphorylation, signal transduction cytoplasm, cytosol, focal adhesion, neuron projection, nucleolus, nucleus ATP binding, heat shock protein binding, protein binding, protein heterodimerization activity, protein kinase activity, protein serine/threonine kinase activity, zinc ion binding Human LIMK2 IntAct UniProtKB {GO:0005515=PMID:22939624, GO:0016310=PMID:8537403, GO:0005801=GO_REF:0000019, GO:0042325=GO_REF:0000002, GO:0005737=PMID:8954941, GO:0004672=GO_REF:0000002, GO:0046982=GO_REF:0000019, GO:0004674=PMID:8537403, GO:0005634=PMID:8954941, GO:0008270=GO_REF:0000002, GO:0007283=GO_REF:0000019, GO:0005524=GO_REF:0000037} P53671 LIM domain kinase 2 protein 20130415 {GO:0005515=IPI, GO:0016310=TAS, GO:0005801=IEA, GO:0042325=IEA, GO:0005737=TAS, GO:0004672=IEA, GO:0046982=IEA, GO:0004674=TAS, GO:0005634=TAS, GO:0008270=IEA, GO:0007283=IEA, GO:0005524=IEA} phosphorylation, regulation of phosphorylation, spermatogenesis cis-Golgi network, cytoplasm, nucleus ATP binding, protein binding, protein heterodimerization activity, protein kinase activity, protein serine/threonine kinase activity, zinc ion binding Human UniProtKB:P08238 LIMS1 IntAct UniProtKB {GO:0005515=PMID:23455922, GO:0048471=PMID:21390327, GO:0005886=GO_REF:0000039, GO:0034329=Reactome:REACT_20676, GO:0007569=PMID:7517666, GO:0071560=PMID:21390327, GO:0008270=PMID:19074270, GO:0045892=PMID:21390327, GO:0005925=PMID:21390327, GO:0005829=Reactome:REACT_20645} P48059 LIM and senescent cell antigen-like-containing domain protein 1 protein 20130415 {GO:0005515=IPI, GO:0048471=IDA, GO:0005886=IEA, GO:0034329=TAS, GO:0007569=TAS, GO:0071560=IEP, GO:0008270=IDA, GO:0045892=IDA, GO:0005925=IDA, GO:0005829=TAS} cell aging, cell junction assembly, cellular response to transforming growth factor beta stimulus, negative regulation of transcription, DNA-dependent cytosol, focal adhesion, perinuclear region of cytoplasm, plasma membrane protein binding, zinc ion binding Human UniProtKB:Q13418 LIMS2 Reactome UniProtKB {GO:0005886=GO_REF:0000039, GO:0034329=Reactome:REACT_20676, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0005925=GO_REF:0000039, GO:0005829=Reactome:REACT_20645} Q7Z4I7 LIM and senescent cell antigen-like-containing domain protein 2 protein 20130301 {GO:0005886=IEA, GO:0034329=TAS, GO:0005634=IEA, GO:0008270=IEA, GO:0005925=IEA, GO:0005829=TAS} cell junction assembly cytosol, focal adhesion, nucleus, plasma membrane zinc ion binding Human LIN28A MGI UniProtKB {GO:0005515=PMID:19703396, GO:0006355=GO_REF:0000002, GO:0010494=PMID:17617744, GO:0003723=PMID:18951094, GO:0045686=GO_REF:0000019, GO:0005730=GO_REF:0000039, GO:0031123=PMID:18951094, GO:0005634=PMID:17617744, GO:0045727=GO_REF:0000019, GO:0003729=GO_REF:0000019, GO:0003677=GO_REF:0000002, GO:0007281=GO_REF:0000019, GO:0010587=PMID:18951094, GO:0060964=GO_REF:0000019, GO:0005737=PMID:20014101, GO:0035198=GO_REF:0000019, GO:0000932=PMID:17617744, GO:0045666=GO_REF:0000019, GO:0031054=PMID:19703396, GO:0019827=PMID:19703396, GO:0008270=GO_REF:0000002, GO:0031369=GO_REF:0000019} Q9H9Z2 Protein lin-28 homolog A protein 20111129 {GO:0005515=IPI, GO:0006355=IEA, GO:0010494=IDA, GO:0003723=IDA, GO:0045686=IEA, GO:0005730=IEA, GO:0031123=IMP, GO:0005634=IDA, GO:0045727=IEA, GO:0003729=IEA, GO:0003677=IEA, GO:0007281=IEA, GO:0010587=IMP, GO:0060964=IEA, GO:0005737=IDA, GO:0035198=IEA, GO:0000932=IDA, GO:0045666=IEA, GO:0031054=IMP, GO:0019827=IMP, GO:0008270=IEA, GO:0031369=IEA} RNA 3'-end processing, germ cell development, miRNA catabolic process, negative regulation of glial cell differentiation, positive regulation of neuron differentiation, positive regulation of translation, pre-miRNA processing, regulation of gene silencing by miRNA, regulation of transcription, DNA-dependent, stem cell maintenance cytoplasm, cytoplasmic mRNA processing body, cytoplasmic stress granule, nucleolus, nucleus DNA binding, RNA binding, mRNA binding, miRNA binding, protein binding, translation initiation factor binding, zinc ion binding Human LIN28B HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005515=PMID:19703396, GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000002, GO:0031054=PMID:19703396, GO:0003723=PMID:19703396, GO:0005730=GO_REF:0000052, GO:0031123=PMID:19703396, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000002, GO:0010587=PMID:19703396} Q6ZN17 Protein lin-28 homolog B protein 20111111 {GO:0005739=IDA, GO:0005515=IPI, GO:0005737=IDA, GO:0006355=IEA, GO:0031054=IMP, GO:0003723=IDA, GO:0005730=IDA, GO:0031123=IMP, GO:0005634=IDA, GO:0008270=IEA, GO:0003677=IEA, GO:0010587=IMP} RNA 3'-end processing, miRNA catabolic process, pre-miRNA processing, regulation of transcription, DNA-dependent cytoplasm, mitochondrion, nucleolus, nucleus DNA binding, RNA binding, protein binding, zinc ion binding Human LIN37 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0005654=Reactome:REACT_111236, GO:0000278=Reactome:REACT_152} Q96GY3 Protein lin-37 homolog protein 20130415 {GO:0005515=IPI, GO:0005654=TAS, GO:0000278=TAS} mitotic cell cycle nucleoplasm protein binding Human UniProtKB:Q8IYF3 LIN52 Reactome UniProtKB {GO:0005654=Reactome:REACT_111236, GO:0000278=Reactome:REACT_152} Q52LA3 Protein lin-52 homolog protein 20110826 {GO:0005654=TAS, GO:0000278=TAS} mitotic cell cycle nucleoplasm Human LIN54 Reactome UniProtKB {GO:0006355=GO_REF:0000037, GO:0005654=Reactome:REACT_111236, GO:0000278=Reactome:REACT_152, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6MZP7 Protein lin-54 homolog protein 20110607 {GO:0006355=IEA, GO:0005654=TAS, GO:0000278=TAS, GO:0003677=IEA, GO:0006351=IEA} mitotic cell cycle, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleoplasm DNA binding Human LIN7A BHF-UCL UniProtKB {GO:0005515=PMID:16855024, GO:0048839=GO_REF:0000019, GO:0014069=GO_REF:0000039, GO:0048489=GO_REF:0000019, GO:0006887=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0030165=GO_REF:0000019, GO:0007269=GO_REF:0000019, GO:0016323=GO_REF:0000039, GO:0006461=PMID:9482110, GO:0045211=GO_REF:0000037, GO:0005923=GO_REF:0000039, GO:0097016=PMID:17237226} O14910 Protein lin-7 homolog A protein 20110403 {GO:0005515=IPI, GO:0048839=IEA, GO:0014069=IEA, GO:0048489=IEA, GO:0006887=IEA, GO:0015031=IEA, GO:0030165=IEA, GO:0007269=IEA, GO:0016323=IEA, GO:0006461=TAS, GO:0045211=IEA, GO:0005923=IEA, GO:0097016=IPI} exocytosis, inner ear development, neurotransmitter secretion, protein complex assembly, protein transport, synaptic vesicle transport basolateral plasma membrane, postsynaptic density, postsynaptic membrane, tight junction L27 domain binding, PDZ domain binding, protein binding Human UniProtKB:Q5T2T1 LIN7B BHF-UCL UniProtKB {GO:0016323=GO_REF:0000039, GO:0045211=GO_REF:0000037, GO:0019904=PMID:17237226, GO:0014069=GO_REF:0000039, GO:0005923=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0006887=GO_REF:0000037, GO:0007269=GO_REF:0000019} Q9HAP6 Protein lin-7 homolog B protein 20110307 {GO:0016323=IEA, GO:0045211=IEA, GO:0019904=IPI, GO:0014069=IEA, GO:0005923=IEA, GO:0015031=IEA, GO:0006887=IEA, GO:0007269=IEA} exocytosis, neurotransmitter secretion, protein transport basolateral plasma membrane, postsynaptic density, postsynaptic membrane, tight junction protein domain specific binding Human UniProtKB:Q5T2T1 LIN7C BHF-UCL UniProtKB {GO:0008092=PMID:17987659, GO:0016323=GO_REF:0000039, GO:0045211=GO_REF:0000037, GO:0019904=PMID:17237226, GO:0014069=GO_REF:0000039, GO:0005923=GO_REF:0000039, GO:0030165=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0006887=GO_REF:0000037, GO:0007269=GO_REF:0000019} Q9NUP9 Protein lin-7 homolog C protein 20110307 {GO:0008092=IPI, GO:0016323=IEA, GO:0045211=IEA, GO:0019904=IPI, GO:0014069=IEA, GO:0005923=IEA, GO:0030165=IEA, GO:0015031=IEA, GO:0006887=IEA, GO:0007269=IEA} exocytosis, neurotransmitter secretion, protein transport basolateral plasma membrane, postsynaptic density, postsynaptic membrane, tight junction PDZ domain binding, cytoskeletal protein binding, protein domain specific binding Human UniProtKB:Q5T2T1 LIN9 HPA UniProtKB {GO:0006260=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005654=Reactome:REACT_111236, GO:0005634=GO_REF:0000052, GO:0000278=Reactome:REACT_152} Q5TKA1 Protein lin-9 homolog protein 20101115 {GO:0006260=IEA, GO:0005730=IDA, GO:0005654=TAS, GO:0005634=IDA, GO:0000278=TAS} DNA replication, mitotic cell cycle nucleolus, nucleoplasm, nucleus NOT Human LINGO1 Reactome UniProtKB {GO:0048011=Reactome:REACT_13776, GO:0005154=GO_REF:0000019, GO:0005886=Reactome:REACT_13496, GO:0048715=GO_REF:0000019, GO:0043491=GO_REF:0000019, GO:0021954=GO_REF:0000019, GO:0050771=Reactome:REACT_13815, GO:0016021=GO_REF:0000037, GO:0050770=Reactome:REACT_13620, GO:0031175=GO_REF:0000019} Q96FE5 Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 protein 20130130 {GO:0048011=TAS, GO:0005154=IEA, GO:0005886=TAS, GO:0048715=IEA, GO:0043491=IEA, GO:0021954=IEA, GO:0050771=TAS, GO:0016021=IEA, GO:0050770=TAS, GO:0031175=IEA} central nervous system neuron development, negative regulation of axonogenesis, negative regulation of oligodendrocyte differentiation, neuron projection development, neurotrophin TRK receptor signaling pathway, protein kinase B signaling cascade, regulation of axonogenesis integral to membrane, plasma membrane epidermal growth factor receptor binding Human LINGO2 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q7L985 Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 LINS null null {} null null null null {} null null null LIPA ENSEMBL UniProtKB {GO:0006629=GO_REF:0000002, GO:0048771=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:0030324=GO_REF:0000019, GO:0016788=GO_REF:0000002, GO:0001816=GO_REF:0000019, GO:0005764=GO_REF:0000039, GO:0016298=PMID:1718995, GO:0016042=GO_REF:0000037, GO:0000902=GO_REF:0000019, GO:0006954=GO_REF:0000019, GO:0048873=GO_REF:0000019, GO:0004771=PMID:1718995} Q5T770 Lysosomal acid lipase/cholesteryl ester hydrolase protein 20130413 {GO:0006629=IEA, GO:0048771=IEA, GO:0008283=IEA, GO:0030324=IEA, GO:0016788=IEA, GO:0001816=IEA, GO:0005764=IEA, GO:0016298=IDA, GO:0016042=IEA, GO:0000902=IEA, GO:0006954=IEA, GO:0048873=IEA, GO:0004771=IDA} cell morphogenesis, cell proliferation, cytokine production, homeostasis of number of cells within a tissue, inflammatory response, lipid catabolic process, lipid metabolic process, lung development, tissue remodeling lysosome hydrolase activity, acting on ester bonds, lipase activity, sterol esterase activity Human Ensembl:ENSMUSP00000053270 LIPC BHF-UCL UniProtKB {GO:0006629=GO_REF:0000002, GO:0042632=PMID:1883393, GO:0004806=PMID:2839510, GO:0043691=PMID:14531818, GO:0030169=GO_REF:0000024, GO:0070328=PMID:1883393, GO:0005576=GO_REF:0000038, GO:0004620=PMID:3244012, GO:0050253=GO_REF:0000003, GO:0005615=PMID:2839510, GO:0034372=PMID:8640403, GO:0034374=PMID:3244012, GO:0034382=PMID:9685400, GO:0034364=GO_REF:0000037, GO:0034373=PMID:2839510, GO:0034375=PMID:3244012, GO:0006633=PMID:182536, GO:0034638=PMID:2839510, GO:0019433=PMID:2839510, GO:0034185=GO_REF:0000024, GO:0008201=GO_REF:0000037, GO:0008203=GO_REF:0000019} P11150 Hepatic triacylglycerol lipase protein 20090210 {GO:0006629=IEA, GO:0042632=IMP, GO:0004806=IDA, GO:0043691=IC, GO:0030169=ISS, GO:0070328=IMP, GO:0005576=IEA, GO:0004620=TAS, GO:0050253=IEA, GO:0005615=IDA, GO:0034372=IDA, GO:0034374=IMP, GO:0034382=TAS, GO:0034364=IEA, GO:0034373=TAS, GO:0034375=IMP, GO:0006633=IDA, GO:0034638=TAS, GO:0019433=IDA, GO:0034185=ISS, GO:0008201=IEA, GO:0008203=IEA} cholesterol homeostasis, cholesterol metabolic process, chylomicron remnant clearance, fatty acid biosynthetic process, high-density lipoprotein particle remodeling, intermediate-density lipoprotein particle remodeling, lipid metabolic process, low-density lipoprotein particle remodeling, phosphatidylcholine catabolic process, reverse cholesterol transport, triglyceride catabolic process, triglyceride homeostasis, very-low-density lipoprotein particle remodeling extracellular region, extracellular space, high-density lipoprotein particle apolipoprotein binding, heparin binding, low-density lipoprotein particle binding, phospholipase activity, retinyl-palmitate esterase activity, triglyceride lipase activity Human LIPE Reactome UniProtKB {GO:0006629=Reactome:REACT_602, GO:0046340=GO_REF:0000019, GO:0005515=PMID:17026959, GO:0005811=GO_REF:0000024, GO:0004806=GO_REF:0000019, GO:0019901=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0016298=GO_REF:0000002, GO:0005829=GO_REF:0000039, GO:0016042=GO_REF:0000024, GO:0016787=GO_REF:0000002, GO:0005901=GO_REF:0000039, GO:0006468=PMID:3420405, GO:0019433=Reactome:REACT_494, GO:0033878=GO_REF:0000003, GO:0008203=GO_REF:0000037} Q05469 Hormone-sensitive lipase protein 20130213 {GO:0006629=TAS, GO:0046340=IEA, GO:0005515=IPI, GO:0005811=ISS, GO:0004806=IEA, GO:0019901=IEA, GO:0044281=TAS, GO:0016298=IEA, GO:0005829=IEA, GO:0016042=ISS, GO:0016787=IEA, GO:0005901=IEA, GO:0006468=TAS, GO:0019433=TAS, GO:0033878=IEA, GO:0008203=IEA} cholesterol metabolic process, diacylglycerol catabolic process, lipid catabolic process, lipid metabolic process, protein phosphorylation, small molecule metabolic process, triglyceride catabolic process caveola, cytosol, lipid particle hormone-sensitive lipase activity, hydrolase activity, lipase activity, protein binding, protein kinase binding, triglyceride lipase activity Human LIPF InterPro UniProtKB {GO:0005739=GO_REF:0000019, GO:0016042=GO_REF:0000037, GO:0004806=PMID:3304425, GO:0016615=GO_REF:0000019, GO:0016788=GO_REF:0000002, GO:0006641=PMID:3304425, GO:0006108=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0050253=GO_REF:0000003, GO:0008289=PMID:2753032} Q5VXI8 cDNA FLJ50254, highly similar to Gastric triacylglycerol lipase (EC 3.1.1.3) protein 20130413 {GO:0005739=IEA, GO:0016042=IEA, GO:0004806=TAS, GO:0016615=IEA, GO:0016788=IEA, GO:0006641=NAS, GO:0006108=IEA, GO:0005576=IEA, GO:0005575=ND, GO:0050253=IEA, GO:0008289=NAS} lipid catabolic process, malate metabolic process, triglyceride metabolic process cellular_component, extracellular region, mitochondrion hydrolase activity, acting on ester bonds, lipid binding, malate dehydrogenase activity, retinyl-palmitate esterase activity, triglyceride lipase activity Human InterPro:IPR025483 LIPG BHF-UCL UniProtKB {GO:0042632=PMID:19136670, GO:0006629=PMID:10318835, GO:0032376=PMID:19136670, GO:0004806=GO_REF:0000003, GO:0007584=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:0043691=PMID:19136670, GO:0005576=GO_REF:0000038, GO:0004620=PMID:10192396, GO:0050253=GO_REF:0000003, GO:0004465=GO_REF:0000002, GO:0005615=PMID:10192396, GO:0050746=GO_REF:0000019, GO:0010983=PMID:19136670, GO:0034375=PMID:19136670, GO:0055091=PMID:19136670, GO:0008970=PMID:10318835, GO:0009395=PMID:19136670, GO:0008201=GO_REF:0000037} Q9Y5X9 Endothelial lipase protein 20090629 {GO:0042632=IMP, GO:0006629=TAS, GO:0032376=IDA, GO:0004806=IEA, GO:0007584=IEA, GO:0008283=IEA, GO:0043691=IMP, GO:0005576=IEA, GO:0004620=IDA, GO:0050253=IEA, GO:0004465=IEA, GO:0005615=IDA, GO:0050746=IEA, GO:0010983=IMP, GO:0034375=IMP, GO:0055091=IMP, GO:0008970=IDA, GO:0009395=NAS, GO:0008201=IEA} cell proliferation, cholesterol homeostasis, high-density lipoprotein particle remodeling, lipid metabolic process, phospholipid catabolic process, phospholipid homeostasis, positive regulation of cholesterol transport, positive regulation of high-density lipoprotein particle clearance, regulation of lipoprotein metabolic process, response to nutrient, reverse cholesterol transport extracellular region, extracellular space heparin binding, lipoprotein lipase activity, phosphatidylcholine 1-acylhydrolase activity, phospholipase activity, retinyl-palmitate esterase activity, triglyceride lipase activity Human LIPH UniProtKB UniProtKB {GO:0016042=PMID:12963729, GO:0006629=GO_REF:0000002, GO:0005886=PMID:12963729, GO:0016787=GO_REF:0000038, GO:0005576=GO_REF:0000038, GO:0004620=PMID:12963729, GO:0003824=GO_REF:0000002, GO:0005615=PMID:12963729, GO:0008201=PMID:12963729} Q8WWY8 Lipase member H protein 20110405 {GO:0016042=IDA, GO:0006629=IEA, GO:0005886=IDA, GO:0016787=IEA, GO:0005576=IEA, GO:0004620=IDA, GO:0003824=IEA, GO:0005615=IDA, GO:0008201=IDA} lipid catabolic process, lipid metabolic process extracellular region, extracellular space, plasma membrane catalytic activity, heparin binding, hydrolase activity, phospholipase activity Human LIPM UniProtKB UniProtKB {GO:0016042=GO_REF:0000037, GO:0016788=GO_REF:0000002, GO:0005576=GO_REF:0000039} Q5VYY2 Lipase member M protein 20130413 {GO:0016042=IEA, GO:0016788=IEA, GO:0005576=IEA} lipid catabolic process extracellular region hydrolase activity, acting on ester bonds Human UniProtKB-SubCell:SL-0243 LIPT1 PINC UniProtKB {GO:0006629=PMID:10103005, GO:0005739=GO_REF:0000039, GO:0016746=GO_REF:0000037, GO:0009249=GO_REF:0000002, GO:0003824=GO_REF:0000002, GO:0006464=PMID:10103005} Q9Y234 Lipoyltransferase 1, mitochondrial protein 20030904 {GO:0006629=TAS, GO:0005739=IEA, GO:0016746=IEA, GO:0009249=IEA, GO:0003824=IEA, GO:0006464=TAS} cellular protein modification process, lipid metabolic process, protein lipoylation mitochondrion catalytic activity, transferase activity, transferring acyl groups Human LITAF GOC UniProtKB {GO:0005515=PMID:16118794, GO:0042347=GO_REF:0000019, GO:0005794=PMID:16118794, GO:0005886=PMID:16118794, GO:0006357=PMID:10200294, GO:0050699=PMID:15064722, GO:0006915=GO_REF:0000037, GO:0005765=PMID:11274176, GO:0001817=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0007165=PMID:12761501, GO:0071222=GO_REF:0000019, GO:0004871=PMID:12761501, GO:0043123=PMID:12761501} Q99732 Lipopolysaccharide-induced tumor necrosis factor-alpha factor protein 20130413 {GO:0005515=IPI, GO:0042347=IEA, GO:0005794=IMP, GO:0005886=IMP, GO:0006357=TAS, GO:0050699=IPI, GO:0006915=IEA, GO:0005765=IDA, GO:0001817=IEA, GO:0006351=IEA, GO:0007165=IMP, GO:0071222=IEA, GO:0004871=IMP, GO:0043123=IMP} apoptotic process, cellular response to lipopolysaccharide, negative regulation of NF-kappaB import into nucleus, positive regulation of I-kappaB kinase/NF-kappaB cascade, regulation of cytokine production, regulation of transcription from RNA polymerase II promoter, signal transduction, transcription, DNA-dependent Golgi apparatus, lysosomal membrane, plasma membrane WW domain binding, protein binding, signal transducer activity Human LLGL1 GOC UniProtKB {GO:0005515=PMID:7542763, GO:0030424=GO_REF:0000024, GO:0019901=PMID:7542763, GO:0032851=GO_REF:0000024, GO:0006893=GO_REF:0000024, GO:0007409=GO_REF:0000024, GO:0006887=GO_REF:0000037, GO:0032588=GO_REF:0000024, GO:0000137=GO_REF:0000024, GO:0005737=PMID:7542763, GO:0006461=PMID:7542763, GO:0000139=GO_REF:0000039, GO:0005198=PMID:7542763, GO:0030866=PMID:7542763, GO:0031901=GO_REF:0000024, GO:0035090=GO_REF:0000019, GO:0030864=PMID:7542763, GO:0005856=PMID:7542763, GO:0005097=GO_REF:0000024, GO:0035748=GO_REF:0000019} Q15334 Lethal(2) giant larvae protein homolog 1 protein 20130413 {GO:0005515=IPI, GO:0030424=ISS, GO:0019901=IDA, GO:0032851=ISS, GO:0006893=ISS, GO:0007409=ISS, GO:0006887=IEA, GO:0032588=ISS, GO:0000137=ISS, GO:0005737=IDA, GO:0006461=IDA, GO:0000139=IEA, GO:0005198=TAS, GO:0030866=IDA, GO:0031901=ISS, GO:0035090=IEA, GO:0030864=IDA, GO:0005856=TAS, GO:0005097=ISS, GO:0035748=IEA} Golgi to plasma membrane transport, axonogenesis, cortical actin cytoskeleton organization, exocytosis, maintenance of apical/basal cell polarity, positive regulation of Rab GTPase activity, protein complex assembly Golgi cis cisterna, Golgi membrane, axon, cortical actin cytoskeleton, cytoplasm, cytoskeleton, early endosome membrane, myelin sheath abaxonal region, trans-Golgi network membrane Rab GTPase activator activity, protein binding, protein kinase binding, structural molecule activity Human UniProtKB:Q8K4K5 LLGL2 HPA UniProtKB {GO:0005515=PMID:12725730, GO:0005737=GO_REF:0000052, GO:0007049=GO_REF:0000037, GO:0032878=PMID:12725730, GO:0030165=PMID:12725730, GO:0006887=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0051301=GO_REF:0000037} Q6P1M3 Lethal(2) giant larvae protein homolog 2 protein 20101115 {GO:0005515=IPI, GO:0005737=IDA, GO:0007049=IEA, GO:0032878=IDA, GO:0030165=IPI, GO:0006887=IEA, GO:0043231=IDA, GO:0051301=IEA} cell cycle, cell division, exocytosis, regulation of establishment or maintenance of cell polarity cytoplasm, intracellular membrane-bounded organelle PDZ domain binding, protein binding Human LLPH null null {} null null null null {} null null null LMAN1 Reactome UniProtKB {GO:0005515=PMID:9774442, GO:0012507=Reactome:REACT_25176, GO:0005793=PMID:15308636, GO:0005537=PMID:7876089, GO:0030017=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0006888=PMID:9546392, GO:0010638=PMID:18287528, GO:0000139=GO_REF:0000039, GO:0007596=PMID:9546392, GO:0006457=PMID:9546392, GO:0034498=PMID:18287528, GO:0033116=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0007030=PMID:18287528, GO:0032527=PMID:18287528, GO:0016021=GO_REF:0000037, GO:0051082=PMID:9546392, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} P49257 Protein ERGIC-53 protein 20101116 {GO:0005515=IPI, GO:0012507=TAS, GO:0005793=IDA, GO:0005537=TAS, GO:0030017=IEA, GO:0046872=IEA, GO:0006888=TAS, GO:0010638=IMP, GO:0000139=IEA, GO:0007596=TAS, GO:0006457=TAS, GO:0034498=IMP, GO:0033116=IEA, GO:0005789=IEA, GO:0007030=IMP, GO:0032527=IMP, GO:0016021=IEA, GO:0051082=TAS, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS} ER to Golgi vesicle-mediated transport, Golgi organization, blood coagulation, cellular protein metabolic process, early endosome to Golgi transport, positive regulation of organelle organization, post-translational protein modification, protein N-linked glycosylation via asparagine, protein exit from endoplasmic reticulum, protein folding ER to Golgi transport vesicle membrane, Golgi membrane, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment, endoplasmic reticulum-Golgi intermediate compartment membrane, integral to membrane, sarcomere mannose binding, metal ion binding, protein binding, unfolded protein binding Human LMAN2 UniProtKB UniProtKB {GO:0005793=PMID:15308636, GO:0000139=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0033116=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q12907 Vesicular integral-membrane protein VIP36 protein 20060116 {GO:0005793=IDA, GO:0000139=IEA, GO:0016020=IEA, GO:0033116=IEA, GO:0005789=IEA, GO:0016021=IEA, GO:0015031=IEA, GO:0046872=IEA} protein transport Golgi membrane, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment, endoplasmic reticulum-Golgi intermediate compartment membrane, integral to membrane, membrane metal ion binding Human LMAN2L UniProtKB UniProtKB {GO:0006888=PMID:12878160, GO:0030134=PMID:12878160, GO:0005794=PMID:12878160, GO:0000139=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0006457=PMID:12609988, GO:0005789=PMID:12609988, GO:0016021=PMID:12609988, GO:0015031=PMID:12878160, GO:0005537=PMID:12609988, GO:0046872=GO_REF:0000037} Q9H0V9 VIP36-like protein protein 20030808 {GO:0006888=TAS, GO:0030134=NAS, GO:0005794=IDA, GO:0000139=IEA, GO:0016020=IEA, GO:0006457=NAS, GO:0005789=IDA, GO:0016021=TAS, GO:0015031=IMP, GO:0005537=TAS, GO:0046872=IEA} ER to Golgi vesicle-mediated transport, protein folding, protein transport ER to Golgi transport vesicle, Golgi apparatus, Golgi membrane, endoplasmic reticulum membrane, integral to membrane, membrane mannose binding, metal ion binding Human LMBR1 ENSEMBL UniProtKB {GO:0016021=GO_REF:0000037, GO:0042733=GO_REF:0000019} Q8WVP7 Limb region 1 protein homolog protein 20130413 {GO:0016021=IEA, GO:0042733=IEA} embryonic digit morphogenesis integral to membrane Human Ensembl:ENSMUSP00000058405 LMBR1L UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0006897=GO_REF:0000037} Q6UX01 Protein LMBR1L protein 20130413 {GO:0005886=IEA, GO:0016021=IEA, GO:0006897=IEA} endocytosis integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 LMBRD1 UniProtKB UniProtKB {GO:0031419=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0006810=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005765=GO_REF:0000039} Q9NUN5 Probable lysosomal cobalamin transporter protein 20130413 {GO:0031419=IEA, GO:0019048=IEA, GO:0006810=IEA, GO:0016021=IEA, GO:0005765=IEA} transport, virus-host interaction integral to membrane, lysosomal membrane cobalamin binding Human UniProtKB-SubCell:SL-0157 LMBRD2 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q68DH5 LMBR1 domain-containing protein 2 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 LMCD1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0003714=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0000122=GO_REF:0000019, GO:0070886=PMID:20026769, GO:0010611=PMID:20026769, GO:0006351=GO_REF:0000037} Q9NZU5 LIM and cysteine-rich domains protein 1 protein 20100203 {GO:0005737=IEA, GO:0003714=ISS, GO:0005634=IEA, GO:0008270=IEA, GO:0000122=IEA, GO:0070886=IMP, GO:0010611=IMP, GO:0006351=IEA} negative regulation of transcription from RNA polymerase II promoter, positive regulation of calcineurin-NFAT signaling cascade, regulation of cardiac muscle hypertrophy, transcription, DNA-dependent cytoplasm, nucleus transcription corepressor activity, zinc ion binding Human LMF2 UniProtKB UniProtKB {GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q9BU23 Lipase maturation factor 2 protein 20130413 {GO:0005789=IEA, GO:0016021=IEA} endoplasmic reticulum membrane, integral to membrane Human UniProtKB-SubCell:SL-0097 LMNA HPA UniProtKB {GO:0005515=PMID:10514485, GO:0005882=GO_REF:0000038, GO:0007077=Reactome:REACT_160255, GO:0034504=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0005635=Reactome:REACT_13476, GO:0090343=PMID:20458013, GO:0005638=GO_REF:0000019, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_160075, GO:0030968=Reactome:REACT_18356, GO:0005737=GO_REF:0000052, GO:0000088=Reactome:REACT_765, GO:0000087=Reactome:REACT_910, GO:0035105=GO_REF:0000019, GO:0030334=GO_REF:0000024, GO:0007084=Reactome:REACT_160113, GO:0030951=GO_REF:0000024, GO:0071456=PMID:20810912, GO:0006915=Reactome:REACT_578, GO:0042981=GO_REF:0000024, GO:0005198=GO_REF:0000002, GO:0055015=GO_REF:0000019, GO:0005654=Reactome:REACT_160221, GO:0000278=Reactome:REACT_152, GO:0006987=Reactome:REACT_18368, GO:0000090=Reactome:REACT_1275, GO:0044267=Reactome:REACT_17015} Q6UYC3 Prelamin-A/C protein 20120912 {GO:0005515=IPI, GO:0005882=IEA, GO:0007077=TAS, GO:0034504=ISS, GO:0005634=IDA, GO:0005635=TAS, GO:0090343=IDA, GO:0005638=IEA, GO:0006921=TAS, GO:0005829=TAS, GO:0030968=TAS, GO:0005737=IDA, GO:0000088=TAS, GO:0000087=TAS, GO:0035105=IEA, GO:0030334=ISS, GO:0007084=TAS, GO:0030951=ISS, GO:0071456=IEP, GO:0006915=TAS, GO:0042981=ISS, GO:0005198=IEA, GO:0055015=IEA, GO:0005654=TAS, GO:0000278=TAS, GO:0006987=TAS, GO:0000090=TAS, GO:0044267=TAS} M phase of mitotic cell cycle, activation of signaling protein activity involved in unfolded protein response, apoptotic process, cellular component disassembly involved in execution phase of apoptosis, cellular protein metabolic process, cellular response to hypoxia, endoplasmic reticulum unfolded protein response, establishment or maintenance of microtubule cytoskeleton polarity, mitotic anaphase, mitotic cell cycle, mitotic nuclear envelope disassembly, mitotic nuclear envelope reassembly, mitotic prophase, positive regulation of cell aging, protein localization to nucleus, regulation of apoptotic process, regulation of cell migration, sterol regulatory element binding protein import into nucleus, ventricular cardiac muscle cell development cytoplasm, cytosol, intermediate filament, lamin filament, nuclear envelope, nucleoplasm, nucleus protein binding, structural molecule activity Human LMNB1 Reactome UniProtKB {GO:0043274=GO_REF:0000019, GO:0005198=GO_REF:0000002, GO:0006915=Reactome:REACT_578, GO:0005637=GO_REF:0000039, GO:0005654=Reactome:REACT_13484, GO:0005635=Reactome:REACT_13484, GO:0006921=Reactome:REACT_995, GO:0005638=GO_REF:0000019} P20700 Lamin-B1 protein 20130301 {GO:0043274=IEA, GO:0005198=IEA, GO:0006915=TAS, GO:0005637=IEA, GO:0005654=TAS, GO:0005635=TAS, GO:0006921=TAS, GO:0005638=IEA} apoptotic process, cellular component disassembly involved in execution phase of apoptosis lamin filament, nuclear envelope, nuclear inner membrane, nucleoplasm phospholipase binding, structural molecule activity Human LMNB2 UniProtKB UniProtKB {GO:0005882=GO_REF:0000038, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005198=GO_REF:0000002, GO:0005652=GO_REF:0000029, GO:0005637=GO_REF:0000039, GO:0005638=GO_REF:0000019} Q03252 Lamin-B2 protein 20061026 {GO:0005882=IEA, GO:0008150=ND, GO:0003674=ND, GO:0005198=IEA, GO:0005652=NAS, GO:0005637=IEA, GO:0005638=IEA} biological_process intermediate filament, lamin filament, nuclear inner membrane, nuclear lamina molecular_function, structural molecule activity Human LMO1 BHF-UCL UniProtKB {GO:0045944=PMID:20855495, GO:0005634=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0000122=GO_REF:0000019} P25800 Rhombotin-1 protein 20110206 {GO:0045944=IMP, GO:0005634=ISS, GO:0008270=IEA, GO:0000122=IEA} negative regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter nucleus zinc ion binding Human LMO2 BHF-UCL UniProtKB {GO:0005515=PMID:16314316, GO:0001102=PMID:16314316, GO:0005667=PMID:16314316, GO:0048037=PMID:16314316, GO:0097067=PMID:19375645, GO:0001190=PMID:16314316, GO:0000977=PMID:16314316, GO:0000981=PMID:16314316, GO:0043425=PMID:16314316, GO:0007275=PMID:1923511, GO:0070888=PMID:16314316, GO:0001228=PMID:16314316, GO:0045647=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0045944=PMID:16314316, GO:0042789=PMID:16314316, GO:0008270=GO_REF:0000002, GO:0035162=GO_REF:0000019} P25791 Rhombotin-2 protein 20120622 {GO:0005515=IPI, GO:0001102=IPI, GO:0005667=IDA, GO:0048037=IPI, GO:0097067=IDA, GO:0001190=IDA, GO:0000977=IDA, GO:0000981=IDA, GO:0043425=IPI, GO:0007275=TAS, GO:0070888=IDA, GO:0001228=IDA, GO:0045647=IEA, GO:0003682=IEA, GO:0045944=IDA, GO:0042789=IDA, GO:0008270=IEA, GO:0035162=IEA} cellular response to thyroid hormone stimulus, embryonic hemopoiesis, mRNA transcription from RNA polymerase II promoter, multicellular organismal development, negative regulation of erythrocyte differentiation, positive regulation of transcription from RNA polymerase II promoter transcription factor complex E-box binding, RNA polymerase II activating transcription factor binding, RNA polymerase II regulatory region sequence-specific DNA binding, RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, bHLH transcription factor binding, chromatin binding, cofactor binding, protein binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, zinc ion binding Human LMO3 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q8TAP4 LIM domain only protein 3 protein 20130413 {GO:0006355=IEA, GO:0008270=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent zinc ion binding Human UniProtKB-KW:KW-0805 LMO4 UniProtKB UniProtKB {GO:0021514=GO_REF:0000019, GO:0050865=GO_REF:0000019, GO:0005667=GO_REF:0000024, GO:0042659=GO_REF:0000019, GO:0003700=PMID:10209267, GO:0021522=GO_REF:0000019, GO:0006366=GO_REF:0000024, GO:0001843=GO_REF:0000024, GO:0003281=GO_REF:0000019, GO:0048538=GO_REF:0000019, GO:0021527=GO_REF:0000019, GO:0031333=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0001158=GO_REF:0000019, GO:0008134=GO_REF:0000024} P61968 LIM domain transcription factor LMO4 protein 20051109 {GO:0021514=IEA, GO:0050865=IEA, GO:0005667=ISS, GO:0042659=IEA, GO:0003700=TAS, GO:0021522=IEA, GO:0006366=ISS, GO:0001843=ISS, GO:0003281=IEA, GO:0048538=IEA, GO:0021527=IEA, GO:0031333=IEA, GO:0045944=IEA, GO:0008270=IEA, GO:0001158=IEA, GO:0008134=ISS} negative regulation of protein complex assembly, neural tube closure, positive regulation of transcription from RNA polymerase II promoter, regulation of cell activation, regulation of cell fate specification, spinal cord association neuron differentiation, spinal cord motor neuron differentiation, thymus development, transcription from RNA polymerase II promoter, ventral spinal cord interneuron differentiation, ventricular septum development transcription factor complex enhancer sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, zinc ion binding Human UniProtKB:P61969 LMO7 PINC UniProtKB {GO:0005737=PMID:9826547, GO:0004842=PMID:10531035, GO:0016567=PMID:10531035, GO:0000151=PMID:10531035, GO:0005634=PMID:9826547, GO:0008270=GO_REF:0000002} Q8WWI1 LIM domain only protein 7 protein 20050308 {GO:0005737=TAS, GO:0004842=NAS, GO:0016567=NAS, GO:0000151=NAS, GO:0005634=TAS, GO:0008270=IEA} protein ubiquitination cytoplasm, nucleus, ubiquitin ligase complex ubiquitin-protein ligase activity, zinc ion binding Human LMOD1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0006936=Reactome:REACT_20558, GO:0016020=PMID:2026759, GO:0003779=GO_REF:0000002, GO:0005856=GO_REF:0000039, GO:0005523=GO_REF:0000002, GO:0005829=Reactome:REACT_20663} P29536 Leiomodin-1 protein 20101115 {GO:0005737=IDA, GO:0006936=TAS, GO:0016020=TAS, GO:0003779=IEA, GO:0005856=IEA, GO:0005523=IEA, GO:0005829=TAS} muscle contraction cytoplasm, cytoskeleton, cytosol, membrane actin binding, tropomyosin binding Human LMTK2 IntAct UniProtKB {GO:0005515=PMID:12393858, GO:0048471=PMID:12832520, GO:0005794=PMID:12832520, GO:0004864=PMID:12393858, GO:0032456=PMID:18029400, GO:0045022=PMID:18429820, GO:0005524=PMID:12393858, GO:0070853=PMID:18029400, GO:0033572=PMID:18429820, GO:0046777=PMID:12393858, GO:0018105=PMID:16887929, GO:0001881=PMID:18429820, GO:0004674=PMID:16887929, GO:0018107=PMID:16887929, GO:0006468=PMID:12393858, GO:0004713=GO_REF:0000002, GO:0016021=PMID:12393858, GO:0055037=PMID:18029400, GO:0005769=PMID:18029400} Q8IWU2 Serine/threonine-protein kinase LMTK2 protein 20130415 {GO:0005515=IPI, GO:0048471=IDA, GO:0005794=IDA, GO:0004864=IDA, GO:0032456=IMP, GO:0045022=IMP, GO:0005524=NAS, GO:0070853=IPI, GO:0033572=IMP, GO:0046777=IDA, GO:0018105=IDA, GO:0001881=IMP, GO:0004674=IDA, GO:0018107=IDA, GO:0006468=IDA, GO:0004713=IEA, GO:0016021=IDA, GO:0055037=IDA, GO:0005769=IDA} early endosome to late endosome transport, endocytic recycling, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, protein autophosphorylation, protein phosphorylation, receptor recycling, transferrin transport Golgi apparatus, early endosome, integral to membrane, perinuclear region of cytoplasm, recycling endosome ATP binding, myosin VI binding, protein binding, protein phosphatase inhibitor activity, protein serine/threonine kinase activity, protein tyrosine kinase activity Human UniProtKB:P41236 LMTK3 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0004674=GO_REF:0000037, GO:0010923=PMID:19389623, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037, GO:0004713=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q96Q04 Serine/threonine-protein kinase LMTK3 protein 20111103 {GO:0008150=ND, GO:0003674=ND, GO:0004674=IEA, GO:0010923=IDA, GO:0005575=ND, GO:0016021=IEA, GO:0004713=IEA, GO:0005524=IEA} biological_process, negative regulation of phosphatase activity cellular_component, integral to membrane ATP binding, molecular_function, protein serine/threonine kinase activity, protein tyrosine kinase activity Human LMX1A UniProtKB UniProtKB {GO:0021542=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0021953=GO_REF:0000019, GO:0021549=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0001558=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0045665=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0071542=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0030901=GO_REF:0000019} Q8TE12 LIM homeobox transcription factor 1-alpha protein 20130413 {GO:0021542=IEA, GO:0003700=IEA, GO:0021953=IEA, GO:0021549=IEA, GO:0005634=IEA, GO:0001558=IEA, GO:0006351=IEA, GO:0043565=IEA, GO:0045665=IEA, GO:0007411=IEA, GO:0071542=IEA, GO:0008270=IEA, GO:0030901=IEA} axon guidance, central nervous system neuron differentiation, cerebellum development, dentate gyrus development, dopaminergic neuron differentiation, midbrain development, negative regulation of neuron differentiation, regulation of cell growth, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB-SubCell:SL-0191 LMX1B UniProtKB UniProtKB {GO:0005515=PMID:12792813, GO:0008219=GO_REF:0000019, GO:0006355=PMID:10767331, GO:0003700=PMID:10767331, GO:0008283=GO_REF:0000019, GO:0021954=GO_REF:0000019, GO:0021587=GO_REF:0000019, GO:0007275=PMID:9618165, GO:0005634=PMID:10767331, GO:0009953=GO_REF:0000024, GO:0001701=PMID:12792813, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0035265=GO_REF:0000019, GO:0030182=GO_REF:0000024, GO:0045944=GO_REF:0000019, GO:0030199=GO_REF:0000019, GO:0071542=GO_REF:0000019, GO:0002930=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0030901=GO_REF:0000019, GO:0001764=GO_REF:0000019, GO:0035108=GO_REF:0000019} O60663 LIM homeobox transcription factor 1-beta protein 20041006 {GO:0005515=IPI, GO:0008219=IEA, GO:0006355=IDA, GO:0003700=IDA, GO:0008283=IEA, GO:0021954=IEA, GO:0021587=IEA, GO:0007275=NAS, GO:0005634=IDA, GO:0009953=ISS, GO:0001701=NAS, GO:0006351=IEA, GO:0043565=IEA, GO:0035265=IEA, GO:0030182=ISS, GO:0045944=IEA, GO:0030199=IEA, GO:0071542=IEA, GO:0002930=IEA, GO:0008270=IEA, GO:0030901=IEA, GO:0001764=IEA, GO:0035108=IEA} cell death, cell proliferation, central nervous system neuron development, cerebellum morphogenesis, collagen fibril organization, dopaminergic neuron differentiation, dorsal/ventral pattern formation, in utero embryonic development, limb morphogenesis, midbrain development, multicellular organismal development, neuron differentiation, neuron migration, organ growth, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, trabecular meshwork development, transcription, DNA-dependent nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB:O88609 LNPEP Reactome UniProtKB {GO:0000209=Reactome:REACT_75842, GO:0002474=Reactome:REACT_75820, GO:0002480=Reactome:REACT_111168, GO:0048471=GO_REF:0000019, GO:0007565=PMID:8550619, GO:0005886=PMID:9177475, GO:0042590=Reactome:REACT_111119, GO:0007267=PMID:8550619, GO:0005576=GO_REF:0000039, GO:0005829=Reactome:REACT_75931, GO:0005622=PMID:15691326, GO:0030163=GO_REF:0000019, GO:0031905=Reactome:REACT_111222, GO:0005887=PMID:9177475, GO:0004177=Reactome:REACT_111222, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0030659=Reactome:REACT_147698, GO:0016044=Reactome:REACT_11123, GO:0008237=GO_REF:0000037} Q9UIQ6 Leucyl-cystinyl aminopeptidase protein 20110328 {GO:0000209=TAS, GO:0002474=TAS, GO:0002480=TAS, GO:0048471=IEA, GO:0007565=TAS, GO:0005886=TAS, GO:0042590=TAS, GO:0007267=TAS, GO:0005576=IEA, GO:0005829=TAS, GO:0005622=IDA, GO:0030163=IEA, GO:0031905=TAS, GO:0005887=TAS, GO:0004177=EXP, GO:0006508=IEA, GO:0008270=IEA, GO:0030659=TAS, GO:0016044=TAS, GO:0008237=IEA} antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent, antigen processing and presentation of peptide antigen via MHC class I, cell-cell signaling, cellular membrane organization, female pregnancy, protein catabolic process, protein polyubiquitination, proteolysis cytoplasmic vesicle membrane, cytosol, early endosome lumen, extracellular region, integral to plasma membrane, intracellular, perinuclear region of cytoplasm, plasma membrane aminopeptidase activity, metallopeptidase activity, zinc ion binding Human LNX1 IntAct UniProtKB {GO:0005515=PMID:20864041, GO:0005737=GO_REF:0000039, GO:0004842=GO_REF:0000019, GO:0042787=GO_REF:0000019, GO:0051260=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0030165=GO_REF:0000019} Q8TBB1 E3 ubiquitin-protein ligase LNX protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0004842=IEA, GO:0042787=IEA, GO:0051260=IEA, GO:0008270=IEA, GO:0030165=IEA} protein homooligomerization, protein ubiquitination involved in ubiquitin-dependent protein catabolic process cytoplasm PDZ domain binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q96M61 LNX2 ENSEMBL UniProtKB {GO:0051260=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0030165=GO_REF:0000019} Q8N448 Ligand of Numb protein X 2 protein 20130413 {GO:0051260=IEA, GO:0008270=IEA, GO:0030165=IEA} protein homooligomerization PDZ domain binding, zinc ion binding Human Ensembl:ENSMUSP00000016664 LOH12CR1 null null {} null null null null {} null null null LONP1 UniProtKB UniProtKB {GO:0042645=PMID:18063578, GO:0005515=PMID:14739292, GO:0003727=PMID:14739292, GO:0004252=GO_REF:0000002, GO:0010044=GO_REF:0000019, GO:0043623=GO_REF:0000019, GO:0005739=GO_REF:0000052, GO:0030163=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0003697=GO_REF:0000033, GO:0005759=PMID:12198491, GO:0051603=PMID:8248235, GO:0070407=PMID:12198491, GO:0006508=GO_REF:0000002, GO:0051260=PMID:14739292, GO:0009725=GO_REF:0000019, GO:0000002=PMID:17420247, GO:0032042=PMID:14739292, GO:0001666=PMID:17418790, GO:0070182=PMID:14739292, GO:0007568=GO_REF:0000019, GO:0051880=PMID:18174225, GO:0005524=GO_REF:0000038, GO:0043565=PMID:14739292, GO:0043531=PMID:14739292, GO:0004176=GO_REF:0000002, GO:0006515=GO_REF:0000002, GO:0070361=PMID:9485316, GO:0034599=PMID:12198491, GO:0007005=PMID:15683722, GO:0070362=PMID:9485316, GO:0070363=PMID:9485316, GO:0070364=PMID:9485316} Q8N8K8 Lon protease homolog protein 20130413 {GO:0042645=IDA, GO:0005515=IPI, GO:0003727=IDA, GO:0004252=IEA, GO:0010044=IEA, GO:0043623=IEA, GO:0005739=IDA, GO:0030163=IEA, GO:0005737=IDA, GO:0003697=IBA, GO:0005759=IMP, GO:0051603=IDA, GO:0070407=IMP, GO:0006508=IEA, GO:0051260=IDA, GO:0009725=IEA, GO:0000002=NAS, GO:0032042=NAS, GO:0001666=IEP, GO:0070182=IPI, GO:0007568=IEA, GO:0051880=IDA, GO:0005524=IEA, GO:0043565=IDA, GO:0043531=IDA, GO:0004176=IEA, GO:0006515=IEA, GO:0070361=IDA, GO:0034599=IC, GO:0007005=IMP, GO:0070362=IDA, GO:0070363=IDA, GO:0070364=IDA} aging, cellular protein complex assembly, cellular response to oxidative stress, misfolded or incompletely synthesized protein catabolic process, mitochondrial DNA metabolic process, mitochondrial genome maintenance, mitochondrion organization, oxidation-dependent protein catabolic process, protein catabolic process, protein homooligomerization, proteolysis, proteolysis involved in cellular protein catabolic process, response to aluminum ion, response to hormone stimulus, response to hypoxia cytoplasm, mitochondrial matrix, mitochondrial nucleoid, mitochondrion ADP binding, ATP binding, ATP-dependent peptidase activity, DNA polymerase binding, G-quadruplex DNA binding, mitochondrial heavy strand promoter anti-sense binding, mitochondrial heavy strand promoter sense binding, mitochondrial light strand promoter anti-sense binding, mitochondrial light strand promoter sense binding, protein binding, sequence-specific DNA binding, serine-type endopeptidase activity, single-stranded DNA binding, single-stranded RNA binding Human UniProtKB-KW:KW-0067 LONP2 HGNC UniProtKB {GO:0005515=PMID:18281296, GO:0014070=GO_REF:0000019, GO:0031998=PMID:22002062, GO:0004252=GO_REF:0000033, GO:0005782=GO_REF:0000033, GO:0006625=PMID:18281296, GO:0005102=PMID:20178365, GO:0005634=GO_REF:0000019, GO:0002020=PMID:22002062, GO:0005524=GO_REF:0000033, GO:0043565=GO_REF:0000033, GO:0030163=GO_REF:0000002, GO:0004176=GO_REF:0000033, GO:0006508=GO_REF:0000002, GO:0007031=PMID:14561759, GO:0008233=PMID:18281296, GO:0006515=GO_REF:0000033, GO:0019899=PMID:18281296, GO:0005777=PMID:14561759, GO:0009295=GO_REF:0000033, GO:0006465=PMID:18281296} Q86WA8 Lon protease homolog 2, peroxisomal protein 20061204 {GO:0005515=IPI, GO:0014070=IEA, GO:0031998=IMP, GO:0004252=IBA, GO:0005782=IBA, GO:0006625=NAS, GO:0005102=IPI, GO:0005634=IEA, GO:0002020=IPI, GO:0005524=IBA, GO:0043565=IBA, GO:0030163=IEA, GO:0004176=IBA, GO:0006508=IEA, GO:0007031=NAS, GO:0008233=IDA, GO:0006515=IBA, GO:0019899=IPI, GO:0005777=IDA, GO:0009295=IBA, GO:0006465=IMP} misfolded or incompletely synthesized protein catabolic process, peroxisome organization, protein catabolic process, protein targeting to peroxisome, proteolysis, regulation of fatty acid beta-oxidation, response to organic cyclic compound, signal peptide processing nucleoid, nucleus, peroxisomal matrix, peroxisome ATP binding, ATP-dependent peptidase activity, enzyme binding, peptidase activity, protease binding, protein binding, receptor binding, sequence-specific DNA binding, serine-type endopeptidase activity Human LONRF1 InterPro UniProtKB {GO:0004176=GO_REF:0000002, GO:0006508=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q17RB8 LON peptidase N-terminal domain and RING finger protein 1 protein 20130413 {GO:0004176=IEA, GO:0006508=IEA, GO:0008270=IEA} proteolysis ATP-dependent peptidase activity, zinc ion binding Human InterPro:IPR001841 LONRF2 InterPro UniProtKB {GO:0004176=GO_REF:0000002, GO:0006508=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q1L5Z9 LON peptidase N-terminal domain and RING finger protein 2 protein 20130413 {GO:0004176=IEA, GO:0006508=IEA, GO:0008270=IEA} proteolysis ATP-dependent peptidase activity, zinc ion binding Human InterPro:IPR001841 LONRF3 IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0004176=GO_REF:0000002, GO:0006508=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q496Y0 LON peptidase N-terminal domain and RING finger protein 3 protein 20130415 {GO:0005515=IPI, GO:0004176=IEA, GO:0006508=IEA, GO:0008270=IEA} proteolysis ATP-dependent peptidase activity, protein binding, zinc ion binding Human UniProtKB:P35232 LOR MGI UniProtKB {GO:0005515=PMID:7592852, GO:0005737=GO_REF:0000039, GO:0018149=PMID:10908733, GO:0030216=PMID:10908733, GO:0005198=PMID:10908733, GO:0005200=GO_REF:0000019, GO:0031424=GO_REF:0000037, GO:0009898=GO_REF:0000019, GO:0005654=GO_REF:0000039, GO:0030674=PMID:10908733, GO:0030280=GO_REF:0000019, GO:0001533=PMID:11698679} P23490 Loricrin protein 20110408 {GO:0005515=IPI, GO:0005737=IEA, GO:0018149=IDA, GO:0030216=IDA, GO:0005198=IDA, GO:0005200=IEA, GO:0031424=IEA, GO:0009898=IEA, GO:0005654=IEA, GO:0030674=IDA, GO:0030280=IEA, GO:0001533=IDA} keratinization, keratinocyte differentiation, peptide cross-linking cornified envelope, cytoplasm, internal side of plasma membrane, nucleoplasm protein binding, protein binding, bridging, structural constituent of cytoskeleton, structural constituent of epidermis, structural molecule activity Human LOX IntAct UniProtKB {GO:0005515=PMID:19570982, GO:0005581=GO_REF:0000019, GO:0001568=GO_REF:0000019, GO:0005507=GO_REF:0000019, GO:0030324=GO_REF:0000019, GO:0004720=GO_REF:0000003, GO:0042493=GO_REF:0000019, GO:0005576=Reactome:REACT_150462, GO:0005634=GO_REF:0000019, GO:0048545=GO_REF:0000019, GO:0005615=GO_REF:0000039, GO:0030198=Reactome:REACT_118779, GO:0030199=GO_REF:0000019, GO:0042060=GO_REF:0000019, GO:0006464=PMID:1685472, GO:0048251=GO_REF:0000019} P28300 Protein-lysine 6-oxidase protein 20130415 {GO:0005515=IPI, GO:0005581=IEA, GO:0001568=IEA, GO:0005507=IEA, GO:0030324=IEA, GO:0004720=IEA, GO:0042493=IEA, GO:0005576=TAS, GO:0005634=IEA, GO:0048545=IEA, GO:0005615=IEA, GO:0030198=TAS, GO:0030199=IEA, GO:0042060=IEA, GO:0006464=TAS, GO:0048251=IEA} blood vessel development, cellular protein modification process, collagen fibril organization, elastic fiber assembly, extracellular matrix organization, lung development, response to drug, response to steroid hormone stimulus, wound healing collagen, extracellular region, extracellular space, nucleus copper ion binding, protein binding, protein-lysine 6-oxidase activity Human UniProtKB:P35555 LOXHD1 GOC UniProtKB {GO:0005262=GO_REF:0000033, GO:0050982=GO_REF:0000033, GO:0016020=GO_REF:0000033, GO:0007605=PMID:19732867, GO:0070588=GO_REF:0000033, GO:0032420=GO_REF:0000024} Q8IVV2 Lipoxygenase homology domain-containing protein 1 protein 20130413 {GO:0005262=IBA, GO:0050982=IBA, GO:0016020=IBA, GO:0007605=IMP, GO:0070588=IBA, GO:0032420=ISS} calcium ion transmembrane transport, detection of mechanical stimulus, sensory perception of sound membrane, stereocilium calcium channel activity Human PANTHER:PTN000093539 LOXL1 Reactome UniProtKB {GO:0016641=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0005507=GO_REF:0000002, GO:0005576=Reactome:REACT_150131, GO:0018277=PMID:7689553, GO:0005615=GO_REF:0000039, GO:0055114=PMID:7689553} Q08397 Lysyl oxidase homolog 1 protein 20111125 {GO:0016641=IEA, GO:0030198=TAS, GO:0005507=IEA, GO:0005576=TAS, GO:0018277=TAS, GO:0005615=IEA, GO:0055114=TAS} extracellular matrix organization, oxidation-reduction process, protein deamination extracellular region, extracellular space copper ion binding, oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor Human LOXL2 PINC UniProtKB {GO:0005515=PMID:16096638, GO:0002040=PMID:21835952, GO:0005634=PMID:16096638, GO:0035064=PMID:22483618, GO:0001837=PMID:16096638, GO:0005615=PMID:23319596, GO:0070492=PMID:23319596, GO:0030199=PMID:21835952, GO:0032332=GO_REF:0000024, GO:0007155=PMID:9079631, GO:0018277=PMID:22483618, GO:0005044=GO_REF:0000002, GO:0001666=GO_REF:0000024, GO:0005694=GO_REF:0000039, GO:0005507=GO_REF:0000002, GO:0004720=PMID:22483618, GO:0003714=PMID:22483618, GO:0007568=PMID:9079631, GO:0016570=PMID:22483618, GO:0009055=PMID:9079631, GO:0006351=GO_REF:0000037, GO:0005604=GO_REF:0000024, GO:0016020=GO_REF:0000002, GO:0043542=PMID:21835952, GO:0003682=PMID:22483618, GO:0001935=PMID:21835952, GO:0046688=PMID:23319596, GO:0045892=PMID:16096638, GO:0006464=PMID:23319596, GO:0055114=PMID:22483618} Q9Y4K0 Lysyl oxidase homolog 2 protein 20030904 {GO:0005515=IPI, GO:0002040=IMP, GO:0005634=TAS, GO:0035064=IDA, GO:0001837=IDA, GO:0005615=IDA, GO:0070492=IDA, GO:0030199=IMP, GO:0032332=ISS, GO:0007155=TAS, GO:0018277=IDA, GO:0005044=IEA, GO:0001666=ISS, GO:0005694=IEA, GO:0005507=IEA, GO:0004720=IDA, GO:0003714=IDA, GO:0007568=TAS, GO:0016570=IDA, GO:0009055=TAS, GO:0006351=IEA, GO:0005604=ISS, GO:0016020=IEA, GO:0043542=IMP, GO:0003682=IDA, GO:0001935=IMP, GO:0046688=IDA, GO:0045892=IDA, GO:0006464=IDA, GO:0055114=IDA} aging, cell adhesion, cellular protein modification process, collagen fibril organization, endothelial cell migration, endothelial cell proliferation, epithelial to mesenchymal transition, histone modification, negative regulation of transcription, DNA-dependent, oxidation-reduction process, positive regulation of chondrocyte differentiation, protein deamination, response to copper ion, response to hypoxia, sprouting angiogenesis, transcription, DNA-dependent basement membrane, chromosome, extracellular space, membrane, nucleus chromatin binding, copper ion binding, electron carrier activity, methylated histone residue binding, oligosaccharide binding, protein binding, protein-lysine 6-oxidase activity, scavenger receptor activity, transcription corepressor activity Human LOXL3 InterPro UniProtKB {GO:0005515=PMID:16096638, GO:0008150=GO_REF:0000015, GO:0016641=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0005507=GO_REF:0000002, GO:0004720=PMID:11284725, GO:0005634=PMID:16096638, GO:0005576=PMID:11284725, GO:0001837=PMID:16096638, GO:0045892=PMID:16096638, GO:0005615=GO_REF:0000039, GO:0005044=GO_REF:0000002} Q6IPL7 Lysyl oxidase homolog 3 protein 20130413 {GO:0005515=IPI, GO:0008150=ND, GO:0016641=IEA, GO:0016020=IEA, GO:0005507=IEA, GO:0004720=NAS, GO:0005634=TAS, GO:0005576=IDA, GO:0001837=IDA, GO:0045892=IDA, GO:0005615=IEA, GO:0005044=IEA} biological_process, epithelial to mesenchymal transition, negative regulation of transcription, DNA-dependent extracellular region, extracellular space, membrane, nucleus copper ion binding, oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor, protein binding, protein-lysine 6-oxidase activity, scavenger receptor activity Human InterPro:IPR001695|InterPro:IPR019828 LOXL4 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0016020=GO_REF:0000002, GO:0005507=GO_REF:0000002, GO:0004720=GO_REF:0000019, GO:0005615=GO_REF:0000039, GO:0005044=GO_REF:0000002} Q96JB6 Lysyl oxidase homolog 4 protein 20130415 {GO:0005515=IPI, GO:0016020=IEA, GO:0005507=IEA, GO:0004720=IEA, GO:0005615=IEA, GO:0005044=IEA} extracellular space, membrane copper ion binding, protein binding, protein-lysine 6-oxidase activity, scavenger receptor activity Human UniProtKB:Q15645 LPA GOC UniProtKB {GO:0006629=Reactome:REACT_602, GO:0004866=PMID:8047165, GO:0004252=PMID:2531657, GO:0008015=PMID:8047165, GO:0034358=PMID:2531657, GO:0005576=Reactome:REACT_6958, GO:0044281=Reactome:REACT_111217, GO:0006898=Reactome:REACT_6934, GO:0010951=PMID:8047165, GO:0006869=GO_REF:0000037, GO:0006508=GO_REF:0000037, GO:0042157=Reactome:REACT_6823, GO:0034185=PMID:9269765, GO:0001968=PMID:2531657, GO:0008201=PMID:2531657} P08519 Apolipoprotein(a) protein 20130413 {GO:0006629=TAS, GO:0004866=TAS, GO:0004252=IDA, GO:0008015=TAS, GO:0034358=IDA, GO:0005576=TAS, GO:0044281=TAS, GO:0006898=TAS, GO:0010951=TAS, GO:0006869=IEA, GO:0006508=IEA, GO:0042157=TAS, GO:0034185=IPI, GO:0001968=IPI, GO:0008201=NAS} blood circulation, lipid metabolic process, lipid transport, lipoprotein metabolic process, negative regulation of endopeptidase activity, proteolysis, receptor-mediated endocytosis, small molecule metabolic process extracellular region, plasma lipoprotein particle apolipoprotein binding, endopeptidase inhibitor activity, fibronectin binding, heparin binding, serine-type endopeptidase activity Human LPAR1 Reactome UniProtKB {GO:0005515=PMID:19306925, GO:0005886=Reactome:REACT_22436, GO:0035025=GO_REF:0000019, GO:0030139=PMID:19306925, GO:0007202=PMID:9804623, GO:0007204=PMID:9804623, GO:0071673=GO_REF:0000019, GO:0001965=GO_REF:0000019, GO:0000187=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0005543=GO_REF:0000019, GO:0043197=GO_REF:0000019, GO:0043198=GO_REF:0000019, GO:0051482=GO_REF:0000019, GO:0043123=PMID:12761501, GO:0060999=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0009986=PMID:19306925, GO:0004930=PMID:8922387, GO:0042552=GO_REF:0000019, GO:0071453=GO_REF:0000019, GO:0032060=GO_REF:0000019, GO:0030165=GO_REF:0000019, GO:0007186=PMID:8922387, GO:0005887=PMID:9070858, GO:0010977=GO_REF:0000019, GO:0070915=GO_REF:0000002, GO:0016021=GO_REF:0000038} Q92633 Lysophosphatidic acid receptor 1 protein 20090430 {GO:0005515=IPI, GO:0005886=TAS, GO:0035025=IEA, GO:0030139=IDA, GO:0007202=TAS, GO:0007204=TAS, GO:0071673=IEA, GO:0001965=IEA, GO:0000187=IEA, GO:0005737=IEA, GO:0005543=IEA, GO:0043197=IEA, GO:0043198=IEA, GO:0051482=IEA, GO:0043123=IEP, GO:0060999=IEA, GO:0043065=IEA, GO:0009986=IDA, GO:0004930=TAS, GO:0042552=IEA, GO:0071453=IEA, GO:0032060=IEA, GO:0030165=IEA, GO:0007186=TAS, GO:0005887=TAS, GO:0010977=IEA, GO:0070915=IEA, GO:0016021=IEA} G-protein coupled receptor signaling pathway, activation of MAPK activity, activation of phospholipase C activity, bleb assembly, cellular response to oxygen levels, elevation of cytosolic calcium ion concentration, elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway, myelination, negative regulation of neuron projection development, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of Rho protein signal transduction, positive regulation of apoptotic process, positive regulation of dendritic spine development, positive regulation of smooth muscle cell chemotaxis cell surface, cytoplasm, dendritic shaft, dendritic spine, endocytic vesicle, integral to membrane, integral to plasma membrane, plasma membrane G-protein alpha-subunit binding, G-protein coupled receptor activity, PDZ domain binding, lysophosphatidic acid receptor activity, phospholipid binding, protein binding Human LPAR2 IntAct UniProtKB {GO:0005515=PMID:16203867, GO:0005886=Reactome:REACT_22436, GO:0009986=PMID:19306925, GO:0004930=PMID:9525886, GO:0035025=GO_REF:0000019, GO:0030139=PMID:19306925, GO:0007202=PMID:9804623, GO:0030165=GO_REF:0000019, GO:0007204=PMID:9804623, GO:0008289=PMID:9525886, GO:0000187=GO_REF:0000019, GO:0007186=PMID:9525886, GO:0005887=PMID:9525886, GO:0016021=GO_REF:0000002, GO:0070915=GO_REF:0000002} Q9HBW0 Lysophosphatidic acid receptor 2 protein 20130415 {GO:0005515=IPI, GO:0005886=TAS, GO:0009986=IDA, GO:0004930=TAS, GO:0035025=IEA, GO:0030139=IDA, GO:0007202=TAS, GO:0030165=IEA, GO:0007204=TAS, GO:0008289=TAS, GO:0000187=IEA, GO:0007186=TAS, GO:0005887=TAS, GO:0016021=IEA, GO:0070915=IEA} G-protein coupled receptor signaling pathway, activation of MAPK activity, activation of phospholipase C activity, elevation of cytosolic calcium ion concentration, positive regulation of Rho protein signal transduction cell surface, endocytic vesicle, integral to membrane, integral to plasma membrane, plasma membrane G-protein coupled receptor activity, PDZ domain binding, lipid binding, lysophosphatidic acid receptor activity, protein binding Human UniProtKB:Q15599 LPAR3 HPA UniProtKB {GO:0005886=GO_REF:0000052, GO:0051928=GO_REF:0000019, GO:0004930=PMID:10488122, GO:0032060=GO_REF:0000019, GO:0007268=PMID:10488122, GO:0007204=PMID:10488122, GO:0043231=GO_REF:0000052, GO:0008289=PMID:10488122, GO:0000187=GO_REF:0000019, GO:0001965=GO_REF:0000019, GO:0005543=GO_REF:0000019, GO:0005887=PMID:10488122, GO:0007187=PMID:10488122, GO:0051482=GO_REF:0000019, GO:0070915=GO_REF:0000002} Q9UBY5 Lysophosphatidic acid receptor 3 protein 20100326 {GO:0005886=IDA, GO:0051928=IEA, GO:0004930=TAS, GO:0032060=IEA, GO:0007268=TAS, GO:0007204=TAS, GO:0043231=IDA, GO:0008289=TAS, GO:0000187=IEA, GO:0001965=IEA, GO:0005543=IEA, GO:0005887=TAS, GO:0007187=TAS, GO:0051482=IEA, GO:0070915=IEA} G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, activation of MAPK activity, bleb assembly, elevation of cytosolic calcium ion concentration, elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway, positive regulation of calcium ion transport, synaptic transmission integral to plasma membrane, intracellular membrane-bounded organelle, plasma membrane G-protein alpha-subunit binding, G-protein coupled receptor activity, lipid binding, lysophosphatidic acid receptor activity, phospholipid binding Human LPAR4 Reactome UniProtKB {GO:0005886=Reactome:REACT_22436, GO:0007186=PMID:9073069, GO:0005887=PMID:9073069, GO:0004930=PMID:9073069, GO:0045028=GO_REF:0000002, GO:0008289=GO_REF:0000037} Q99677 Lysophosphatidic acid receptor 4 protein 20100217 {GO:0005886=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0004930=TAS, GO:0045028=IEA, GO:0008289=IEA} G-protein coupled receptor signaling pathway integral to plasma membrane, plasma membrane G-protein coupled purinergic nucleotide receptor activity, G-protein coupled receptor activity, lipid binding Human LPAR6 Reactome UniProtKB {GO:0005886=Reactome:REACT_22436, GO:0007186=GO_REF:0000029, GO:0004930=GO_REF:0000029, GO:0045028=GO_REF:0000002, GO:0016021=GO_REF:0000037} P43657 Lysophosphatidic acid receptor 6 protein 20100217 {GO:0005886=TAS, GO:0007186=NAS, GO:0004930=NAS, GO:0045028=IEA, GO:0016021=IEA} G-protein coupled receptor signaling pathway integral to membrane, plasma membrane G-protein coupled purinergic nucleotide receptor activity, G-protein coupled receptor activity Human LPCAT1 Reactome UniProtKB {GO:0045732=GO_REF:0000019, GO:0005794=GO_REF:0000024, GO:0047184=GO_REF:0000024, GO:0060041=GO_REF:0000019, GO:0005783=GO_REF:0000024, GO:0036148=Reactome:REACT_121324, GO:0005509=GO_REF:0000002, GO:2001246=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0008654=GO_REF:0000024, GO:0047192=GO_REF:0000003, GO:0000139=GO_REF:0000039, GO:0019432=Reactome:REACT_1190, GO:0005789=Reactome:REACT_121363, GO:0043129=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0006654=Reactome:REACT_120906, GO:0044255=Reactome:REACT_22279, GO:0036151=Reactome:REACT_120829, GO:0046474=Reactome:REACT_121401} Q8NF37 Lysophosphatidylcholine acyltransferase 1 protein 20130301 {GO:0045732=IEA, GO:0005794=ISS, GO:0047184=ISS, GO:0060041=IEA, GO:0005783=ISS, GO:0036148=TAS, GO:0005509=IEA, GO:2001246=IEA, GO:0044281=TAS, GO:0008654=ISS, GO:0047192=IEA, GO:0000139=IEA, GO:0019432=TAS, GO:0005789=TAS, GO:0043129=IEA, GO:0016021=IEA, GO:0006644=TAS, GO:0006654=TAS, GO:0044255=TAS, GO:0036151=TAS, GO:0046474=TAS} cellular lipid metabolic process, glycerophospholipid biosynthetic process, negative regulation of phosphatidylcholine biosynthetic process, phosphatidic acid biosynthetic process, phosphatidylcholine acyl-chain remodeling, phosphatidylglycerol acyl-chain remodeling, phospholipid biosynthetic process, phospholipid metabolic process, positive regulation of protein catabolic process, retina development in camera-type eye, small molecule metabolic process, surfactant homeostasis, triglyceride biosynthetic process Golgi apparatus, Golgi membrane, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane 1-acylglycerophosphocholine O-acyltransferase activity, 1-alkylglycerophosphocholine O-acetyltransferase activity, calcium ion binding Human LPCAT2 HPA UniProtKB {GO:0016746=GO_REF:0000002, GO:0047184=GO_REF:0000024, GO:0005795=GO_REF:0000024, GO:0005783=GO_REF:0000052, GO:0006663=GO_REF:0000024, GO:0005509=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0047192=GO_REF:0000024, GO:0000139=GO_REF:0000039, GO:0005789=Reactome:REACT_120871, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0016044=GO_REF:0000024, GO:0036151=Reactome:REACT_120829, GO:0046474=Reactome:REACT_121401} Q7L5N7 Lysophosphatidylcholine acyltransferase 2 protein 20101115 {GO:0016746=IEA, GO:0047184=ISS, GO:0005795=ISS, GO:0005783=IDA, GO:0006663=ISS, GO:0005509=IEA, GO:0044281=TAS, GO:0047192=ISS, GO:0000139=IEA, GO:0005789=TAS, GO:0016021=IEA, GO:0006644=TAS, GO:0016044=ISS, GO:0036151=TAS, GO:0046474=TAS} cellular membrane organization, glycerophospholipid biosynthetic process, phosphatidylcholine acyl-chain remodeling, phospholipid metabolic process, platelet activating factor biosynthetic process, small molecule metabolic process Golgi membrane, Golgi stack, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane 1-acylglycerophosphocholine O-acyltransferase activity, 1-alkylglycerophosphocholine O-acetyltransferase activity, calcium ion binding, transferase activity, transferring acyl groups Human LPCAT3 Reactome UniProtKB {GO:0036150=Reactome:REACT_121384, GO:0047184=PMID:22511767, GO:0016746=GO_REF:0000038, GO:0005789=Reactome:REACT_121340, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0036151=Reactome:REACT_120829, GO:0046474=Reactome:REACT_121401, GO:0036152=Reactome:REACT_121369} Q6P1A2 Lysophospholipid acyltransferase 5 protein 20130301 {GO:0036150=TAS, GO:0047184=IMP, GO:0016746=IEA, GO:0005789=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0006644=TAS, GO:0036151=TAS, GO:0046474=TAS, GO:0036152=TAS} glycerophospholipid biosynthetic process, phosphatidylcholine acyl-chain remodeling, phosphatidylethanolamine acyl-chain remodeling, phosphatidylserine acyl-chain remodeling, phospholipid metabolic process, small molecule metabolic process endoplasmic reticulum membrane, integral to membrane 1-acylglycerophosphocholine O-acyltransferase activity, transferase activity, transferring acyl groups Human LPCAT4 Reactome UniProtKB {GO:0005509=GO_REF:0000002, GO:0036148=Reactome:REACT_121324, GO:0044281=Reactome:REACT_111217, GO:0050200=GO_REF:0000003, GO:0036150=Reactome:REACT_121384, GO:0005789=Reactome:REACT_121363, GO:0019432=Reactome:REACT_1190, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0006654=Reactome:REACT_120906, GO:0036151=Reactome:REACT_120829, GO:0044255=Reactome:REACT_22279, GO:0046474=Reactome:REACT_121401, GO:0036152=Reactome:REACT_121369} Q643R3 Lysophospholipid acyltransferase LPCAT4 protein 20130301 {GO:0005509=IEA, GO:0036148=TAS, GO:0044281=TAS, GO:0050200=IEA, GO:0036150=TAS, GO:0005789=TAS, GO:0019432=TAS, GO:0016021=IEA, GO:0006644=TAS, GO:0006654=TAS, GO:0036151=TAS, GO:0044255=TAS, GO:0046474=TAS, GO:0036152=TAS} cellular lipid metabolic process, glycerophospholipid biosynthetic process, phosphatidic acid biosynthetic process, phosphatidylcholine acyl-chain remodeling, phosphatidylethanolamine acyl-chain remodeling, phosphatidylglycerol acyl-chain remodeling, phosphatidylserine acyl-chain remodeling, phospholipid metabolic process, small molecule metabolic process, triglyceride biosynthetic process endoplasmic reticulum membrane, integral to membrane calcium ion binding, plasmalogen synthase activity Human LPGAT1 Reactome UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005737=PMID:10942595, GO:0016746=GO_REF:0000037, GO:0036148=Reactome:REACT_121324, GO:0005789=Reactome:REACT_121363, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0046474=Reactome:REACT_121401} Q92604 Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 protein 20130301 {GO:0008150=ND, GO:0003674=ND, GO:0005737=IDA, GO:0016746=IEA, GO:0036148=TAS, GO:0005789=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0006644=TAS, GO:0046474=TAS} biological_process, glycerophospholipid biosynthetic process, phosphatidylglycerol acyl-chain remodeling, phospholipid metabolic process, small molecule metabolic process cytoplasm, endoplasmic reticulum membrane, integral to membrane molecular_function, transferase activity, transferring acyl groups Human LPHN1 IntAct UniProtKB {GO:0005515=PMID:21078624, GO:0043005=GO_REF:0000024, GO:0030424=GO_REF:0000024, GO:0090129=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0035584=GO_REF:0000024, GO:0005886=GO_REF:0000024, GO:0004930=GO_REF:0000037, GO:0045202=GO_REF:0000024, GO:0030426=GO_REF:0000024, GO:0042734=GO_REF:0000024, GO:0007186=PMID:15203201, GO:0016020=GO_REF:0000002, GO:0007218=GO_REF:0000002, GO:0016524=GO_REF:0000024, GO:0030246=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0050839=GO_REF:0000024, GO:0007157=GO_REF:0000024} O94910 Latrophilin-1 protein 20130415 {GO:0005515=IPI, GO:0043005=ISS, GO:0030424=ISS, GO:0090129=ISS, GO:0030054=IEA, GO:0035584=ISS, GO:0005886=ISS, GO:0004930=IEA, GO:0045202=ISS, GO:0030426=ISS, GO:0042734=ISS, GO:0007186=TAS, GO:0016020=IEA, GO:0007218=IEA, GO:0016524=ISS, GO:0030246=IEA, GO:0016021=IEA, GO:0050839=ISS, GO:0007157=ISS} G-protein coupled receptor signaling pathway, calcium-mediated signaling using intracellular calcium source, heterophilic cell-cell adhesion, neuropeptide signaling pathway, positive regulation of synapse maturation axon, cell junction, growth cone, integral to membrane, membrane, neuron projection, plasma membrane, presynaptic membrane, synapse G-protein coupled receptor activity, carbohydrate binding, cell adhesion molecule binding, latrotoxin receptor activity, protein binding Human UniProtKB:O00555 LPHN2 UniProtKB UniProtKB {GO:0007186=PMID:10030676, GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0007218=GO_REF:0000002, GO:0016524=PMID:10030676, GO:0030246=GO_REF:0000002, GO:0016021=PMID:10030676} O95490 Latrophilin-2 protein 20011004 {GO:0007186=NAS, GO:0005886=IEA, GO:0004930=IEA, GO:0007218=IEA, GO:0016524=NAS, GO:0030246=IEA, GO:0016021=NAS} G-protein coupled receptor signaling pathway, neuropeptide signaling pathway integral to membrane, plasma membrane G-protein coupled receptor activity, carbohydrate binding, latrotoxin receptor activity Human LPHN3 UniProtKB UniProtKB {GO:0007186=PMID:10994649, GO:0005886=GO_REF:0000039, GO:0004930=PMID:10994649, GO:0007218=GO_REF:0000002, GO:0030246=GO_REF:0000002, GO:0016021=PMID:10994649} Q9HAR2 Latrophilin-3 protein 20011004 {GO:0007186=NAS, GO:0005886=IEA, GO:0004930=NAS, GO:0007218=IEA, GO:0030246=IEA, GO:0016021=NAS} G-protein coupled receptor signaling pathway, neuropeptide signaling pathway integral to membrane, plasma membrane G-protein coupled receptor activity, carbohydrate binding Human LPIN1 Reactome UniProtKB {GO:0006646=Reactome:REACT_120919, GO:0042826=GO_REF:0000019, GO:0045598=GO_REF:0000019, GO:0031100=GO_REF:0000019, GO:0005634=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0042975=GO_REF:0000019, GO:0031529=GO_REF:0000019, GO:0009062=GO_REF:0000024, GO:0005829=GO_REF:0000039, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000024, GO:0045944=GO_REF:0000019, GO:0001085=GO_REF:0000019, GO:0019432=Reactome:REACT_1190, GO:0044255=Reactome:REACT_22279, GO:0006656=Reactome:REACT_121238, GO:0005667=GO_REF:0000019, GO:0032869=GO_REF:0000019, GO:0031965=GO_REF:0000024, GO:0031532=GO_REF:0000019, GO:0000266=GO_REF:0000019, GO:0003713=GO_REF:0000019, GO:0008195=GO_REF:0000003, GO:0000122=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0031065=GO_REF:0000019, GO:0005789=Reactome:REACT_120792, GO:0006644=Reactome:REACT_120870, GO:0006642=GO_REF:0000024, GO:0046474=Reactome:REACT_121401} Q14693 Phosphatidate phosphatase LPIN1 protein 20111102 {GO:0006646=TAS, GO:0042826=IEA, GO:0045598=IEA, GO:0031100=IEA, GO:0005634=ISS, GO:0044281=TAS, GO:0042975=IEA, GO:0031529=IEA, GO:0009062=ISS, GO:0005829=IEA, GO:0003674=ND, GO:0005737=ISS, GO:0045944=IEA, GO:0001085=IEA, GO:0019432=TAS, GO:0044255=TAS, GO:0006656=TAS, GO:0005667=IEA, GO:0032869=IEA, GO:0031965=ISS, GO:0031532=IEA, GO:0000266=IEA, GO:0003713=IEA, GO:0008195=IEA, GO:0000122=IEA, GO:0006351=IEA, GO:0031065=IEA, GO:0005789=TAS, GO:0006644=TAS, GO:0006642=ISS, GO:0046474=TAS} actin cytoskeleton reorganization, cellular lipid metabolic process, cellular response to insulin stimulus, fatty acid catabolic process, glycerophospholipid biosynthetic process, mitochondrial fission, negative regulation of transcription from RNA polymerase II promoter, organ regeneration, phosphatidylcholine biosynthetic process, phosphatidylethanolamine biosynthetic process, phospholipid metabolic process, positive regulation of histone deacetylation, positive regulation of transcription from RNA polymerase II promoter, regulation of fat cell differentiation, ruffle organization, small molecule metabolic process, transcription, DNA-dependent, triglyceride biosynthetic process, triglyceride mobilization cytoplasm, cytosol, endoplasmic reticulum membrane, nuclear membrane, nucleus, transcription factor complex RNA polymerase II transcription factor binding, histone deacetylase binding, molecular_function, peroxisome proliferator activated receptor binding, phosphatidate phosphatase activity, transcription coactivator activity Human LPIN2 Reactome UniProtKB {GO:0006629=GO_REF:0000024, GO:0006646=Reactome:REACT_120919, GO:0003713=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0008195=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0005829=GO_REF:0000039, GO:0045944=GO_REF:0000024, GO:0005789=Reactome:REACT_120792, GO:0006631=GO_REF:0000037, GO:0019432=Reactome:REACT_1190, GO:0006644=Reactome:REACT_120870, GO:0044255=Reactome:REACT_22279, GO:0046474=Reactome:REACT_121401, GO:0006656=Reactome:REACT_121238} Q92539 Phosphatidate phosphatase LPIN2 protein 20111102 {GO:0006629=ISS, GO:0006646=TAS, GO:0003713=ISS, GO:0005634=IEA, GO:0044281=TAS, GO:0008195=ISS, GO:0006351=IEA, GO:0005829=IEA, GO:0045944=ISS, GO:0005789=TAS, GO:0006631=IEA, GO:0019432=TAS, GO:0006644=TAS, GO:0044255=TAS, GO:0046474=TAS, GO:0006656=TAS} cellular lipid metabolic process, fatty acid metabolic process, glycerophospholipid biosynthetic process, lipid metabolic process, phosphatidylcholine biosynthetic process, phosphatidylethanolamine biosynthetic process, phospholipid metabolic process, positive regulation of transcription from RNA polymerase II promoter, small molecule metabolic process, transcription, DNA-dependent, triglyceride biosynthetic process cytosol, endoplasmic reticulum membrane, nucleus phosphatidate phosphatase activity, transcription coactivator activity Human LPL BHF-UCL UniProtKB {GO:0005515=PMID:20124439, GO:0006629=Reactome:REACT_602, GO:0004806=PMID:182536, GO:0005886=GO_REF:0000039, GO:0007603=Reactome:REACT_160125, GO:0042627=GO_REF:0000037, GO:0070328=PMID:17018885, GO:0031225=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0005615=PMID:12573449, GO:0034361=GO_REF:0000037, GO:0019432=GO_REF:0000019, GO:0006633=PMID:182536, GO:0019433=PMID:182536, GO:0008201=PMID:12573449, GO:0009986=GO_REF:0000019, GO:0010744=PMID:12573449, GO:0042493=GO_REF:0000019, GO:0005102=PMID:10085125, GO:0005576=Reactome:REACT_160186, GO:0004620=PMID:10727238, GO:0010886=PMID:12573449, GO:0004465=PMID:3973011, GO:0001523=Reactome:REACT_24968, GO:0031012=GO_REF:0000019, GO:0034372=PMID:3973011, GO:0034371=PMID:3973011, GO:0010890=PMID:12573449, GO:0042157=Reactome:REACT_6841, GO:0006641=PMID:10727238, GO:0034185=PMID:15178420, GO:0006644=PMID:10727238, GO:0017129=GO_REF:0000019} P06858 Lipoprotein lipase protein 20121031 {GO:0005515=IPI, GO:0006629=TAS, GO:0004806=IDA, GO:0005886=IEA, GO:0007603=TAS, GO:0042627=IEA, GO:0070328=IGI, GO:0031225=IEA, GO:0044281=TAS, GO:0005615=IDA, GO:0034361=IEA, GO:0019432=IEA, GO:0006633=IDA, GO:0019433=IDA, GO:0008201=IDA, GO:0009986=IEA, GO:0010744=IC, GO:0042493=IEA, GO:0005102=IPI, GO:0005576=TAS, GO:0004620=ISS, GO:0010886=IMP, GO:0004465=IDA, GO:0001523=TAS, GO:0031012=IEA, GO:0034372=IDA, GO:0034371=IC, GO:0010890=IMP, GO:0042157=TAS, GO:0006641=ISS, GO:0034185=IPI, GO:0006644=ISS, GO:0017129=IEA} chylomicron remodeling, fatty acid biosynthetic process, lipid metabolic process, lipoprotein metabolic process, phospholipid metabolic process, phototransduction, visible light, positive regulation of cholesterol storage, positive regulation of macrophage derived foam cell differentiation, positive regulation of sequestering of triglyceride, response to drug, retinoid metabolic process, small molecule metabolic process, triglyceride biosynthetic process, triglyceride catabolic process, triglyceride homeostasis, triglyceride metabolic process, very-low-density lipoprotein particle remodeling anchored to membrane, cell surface, chylomicron, extracellular matrix, extracellular region, extracellular space, plasma membrane, very-low-density lipoprotein particle apolipoprotein binding, heparin binding, lipoprotein lipase activity, phospholipase activity, protein binding, receptor binding, triglyceride binding, triglyceride lipase activity Human UniProtKB:Q6Q788 LPO UniProtKB UniProtKB {GO:0004601=GO_REF:0000003, GO:0005575=GO_REF:0000015, GO:0042744=GO_REF:0000037, GO:0005615=GO_REF:0000039, GO:0006979=PMID:8964511, GO:0046872=GO_REF:0000037, GO:0020037=GO_REF:0000002} P22079 Lactoperoxidase protein 20061026 {GO:0004601=IEA, GO:0005575=ND, GO:0042744=IEA, GO:0005615=IEA, GO:0006979=NAS, GO:0046872=IEA, GO:0020037=IEA} hydrogen peroxide catabolic process, response to oxidative stress cellular_component, extracellular space heme binding, metal ion binding, peroxidase activity Human LPP HPA UniProtKB {GO:0005515=PMID:15649318, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0007155=GO_REF:0000037, GO:0005925=GO_REF:0000052} Q93052 Lipoma-preferred partner protein 20101115 {GO:0005515=IPI, GO:0008150=ND, GO:0005737=IDA, GO:0005886=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0007155=IEA, GO:0005925=IDA} biological_process, cell adhesion cytoplasm, focal adhesion, nucleus, plasma membrane protein binding, zinc ion binding Human LPXN PINC UniProtKB {GO:0003712=PMID:18451096, GO:0005515=PMID:18451096, GO:0033628=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0048471=GO_REF:0000039, GO:0005886=PMID:17640867, GO:0050859=PMID:17640867, GO:0002102=PMID:12674328, GO:0005634=PMID:18451096, GO:0042995=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0007165=PMID:9565592, GO:0007162=PMID:20543562, GO:0005737=PMID:18451096, GO:0006461=PMID:9565592, GO:0008270=GO_REF:0000002, GO:0007155=GO_REF:0000037, GO:0005925=PMID:20543562} O60711 Leupaxin protein 20030904 {GO:0003712=IDA, GO:0005515=IPI, GO:0033628=IEA, GO:0006355=IEA, GO:0048471=IEA, GO:0005886=IDA, GO:0050859=IDA, GO:0002102=IDA, GO:0005634=IDA, GO:0042995=IEA, GO:0006351=IEA, GO:0007165=TAS, GO:0007162=IDA, GO:0005737=IDA, GO:0006461=TAS, GO:0008270=IEA, GO:0007155=IEA, GO:0005925=IDA} cell adhesion, negative regulation of B cell receptor signaling pathway, negative regulation of cell adhesion, protein complex assembly, regulation of cell adhesion mediated by integrin, regulation of transcription, DNA-dependent, signal transduction, transcription, DNA-dependent cell projection, cytoplasm, focal adhesion, nucleus, perinuclear region of cytoplasm, plasma membrane, podosome protein binding, transcription cofactor activity, zinc ion binding Human LRAT Reactome UniProtKB {GO:0005791=GO_REF:0000024, GO:0047173=GO_REF:0000003, GO:0048471=GO_REF:0000024, GO:0016746=PMID:9920938, GO:0007603=Reactome:REACT_160125, GO:0005771=GO_REF:0000024, GO:0009790=GO_REF:0000019, GO:0001523=Reactome:REACT_160156, GO:0019841=GO_REF:0000019, GO:0006776=GO_REF:0000019, GO:0042573=GO_REF:0000019, GO:0001972=GO_REF:0000019, GO:0042572=GO_REF:0000041, GO:0005789=Reactome:REACT_160266, GO:0016021=GO_REF:0000037, GO:0007601=GO_REF:0000037} O95237 Lecithin retinol acyltransferase protein 20130301 {GO:0005791=ISS, GO:0047173=IEA, GO:0048471=ISS, GO:0016746=TAS, GO:0007603=TAS, GO:0005771=ISS, GO:0009790=IEA, GO:0001523=TAS, GO:0019841=IEA, GO:0006776=IEA, GO:0042573=IEA, GO:0001972=IEA, GO:0042572=IEA, GO:0005789=TAS, GO:0016021=IEA, GO:0007601=IEA} embryo development, phototransduction, visible light, retinoic acid metabolic process, retinoid metabolic process, retinol metabolic process, visual perception, vitamin A metabolic process endoplasmic reticulum membrane, integral to membrane, multivesicular body, perinuclear region of cytoplasm, rough endoplasmic reticulum phosphatidylcholine-retinol O-acyltransferase activity, retinoic acid binding, retinol binding, transferase activity, transferring acyl groups Human LRBA UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005794=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0005783=GO_REF:0000039, GO:0016023=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037, GO:0005764=GO_REF:0000039} P50851 Lipopolysaccharide-responsive and beige-like anchor protein protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0005794=IEA, GO:0005886=IEA, GO:0005783=IEA, GO:0016023=IEA, GO:0005575=ND, GO:0016021=IEA, GO:0005764=IEA} biological_process Golgi apparatus, cellular_component, cytoplasmic membrane-bounded vesicle, endoplasmic reticulum, integral to membrane, lysosome, plasma membrane molecular_function Human LRCH1 null null {} null null null null {} null null null LRCH2 null null {} null null null null {} null null null LRCH3 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q96II8 Leucine-rich repeat and calponin homology domain-containing protein 3 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 LRCH4 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0016605=PMID:16449650, GO:0007399=PMID:9799793} O75427 Leucine-rich repeat and calponin homology domain-containing protein 4 protein 20130415 {GO:0005515=IPI, GO:0016605=IDA, GO:0007399=TAS} nervous system development PML body protein binding Human UniProtKB:Q99750 LRFN1 UniProtKB UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000037, GO:0045211=GO_REF:0000037, GO:0014069=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q9P244 Leucine-rich repeat and fibronectin type III domain-containing protein 1 protein 20130413 {GO:0030054=IEA, GO:0005886=IEA, GO:0045211=IEA, GO:0014069=IEA, GO:0016021=IEA} cell junction, integral to membrane, plasma membrane, postsynaptic density, postsynaptic membrane Human UniProtKB-SubCell:SL-0297 LRG1 MGI UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0016020=PMID:3856868, GO:0050873=GO_REF:0000019, GO:0005576=PMID:14718574, GO:0005615=PMID:20363744} P02750 Leucine-rich alpha-2-glycoprotein protein 20120508 {GO:0008150=ND, GO:0003674=ND, GO:0016020=NAS, GO:0050873=IEA, GO:0005576=NAS, GO:0005615=IDA} biological_process, brown fat cell differentiation extracellular region, extracellular space, membrane molecular_function Human LRIF1 HPA UniProtKB {GO:0005515=PMID:15383276, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0042974=GO_REF:0000002, GO:0016363=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q5T3J3 Ligand-dependent nuclear receptor-interacting factor 1 protein 20111111 {GO:0005515=IPI, GO:0006355=IEA, GO:0005634=IDA, GO:0042974=IEA, GO:0016363=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nuclear matrix, nucleus protein binding, retinoic acid receptor binding Human LRIG1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q96JA1 Leucine-rich repeats and immunoglobulin-like domains protein 1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 LRIG2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037} O94898 Leucine-rich repeats and immunoglobulin-like domains protein 2 protein 20130413 {GO:0005737=IEA, GO:0005886=IEA, GO:0016021=IEA} cytoplasm, integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 LRIG3 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0030659=GO_REF:0000039} Q6UXM1 Leucine-rich repeats and immunoglobulin-like domains protein 3 protein 20130413 {GO:0005886=IEA, GO:0007275=IEA, GO:0016021=IEA, GO:0030659=IEA} multicellular organismal development cytoplasmic vesicle membrane, integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0089 LRIT1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0030176=GO_REF:0000024} Q9P2V4 Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1 protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0030176=ISS} biological_process integral to endoplasmic reticulum membrane molecular_function Human LRMP PINC UniProtKB {GO:0005887=PMID:8021504, GO:0005789=GO_REF:0000039, GO:0016021=PMID:8798562, GO:0006906=PMID:8021504, GO:0006903=PMID:8021504} Q12912 Lymphoid-restricted membrane protein protein 20030904 {GO:0005887=TAS, GO:0005789=IEA, GO:0016021=TAS, GO:0006906=TAS, GO:0006903=TAS} vesicle fusion, vesicle targeting endoplasmic reticulum membrane, integral to membrane, integral to plasma membrane Human LRP1 InterPro UniProtKB {GO:0005515=PMID:17326667, GO:0007603=Reactome:REACT_160125, GO:0005886=Reactome:REACT_160272, GO:0097242=PMID:19098903, GO:0030178=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0070325=PMID:18635818, GO:0032403=PMID:8626514, GO:0010875=GO_REF:0000024, GO:0014912=GO_REF:0000024, GO:0042953=PMID:3266596, GO:0032956=GO_REF:0000024, GO:0004872=PMID:10880251, GO:0042954=PMID:3266596, GO:0008203=GO_REF:0000019, GO:2000587=GO_REF:0000024, GO:0032429=GO_REF:0000024, GO:0032374=GO_REF:0000024, GO:0005509=GO_REF:0000002, GO:0032370=GO_REF:0000024, GO:0035909=GO_REF:0000024, GO:0043277=GO_REF:0000024, GO:0001523=Reactome:REACT_24968, GO:0006898=GO_REF:0000019, GO:0030666=Reactome:REACT_160232, GO:0005905=GO_REF:0000039, GO:0005887=GO_REF:0000024, GO:0016021=GO_REF:0000038, GO:0034185=PMID:18635818} Q86SW0 Low-density lipoprotein receptor-related protein 1 85 kDa subunit protein 20130413 {GO:0005515=IPI, GO:0007603=TAS, GO:0005886=TAS, GO:0097242=TAS, GO:0030178=ISS, GO:0005634=IEA, GO:0070325=IC, GO:0032403=IDA, GO:0010875=ISS, GO:0014912=ISS, GO:0042953=NAS, GO:0032956=ISS, GO:0004872=TAS, GO:0042954=NAS, GO:0008203=IEA, GO:2000587=ISS, GO:0032429=ISS, GO:0032374=ISS, GO:0005509=IEA, GO:0032370=ISS, GO:0035909=ISS, GO:0043277=ISS, GO:0001523=TAS, GO:0006898=IEA, GO:0030666=TAS, GO:0005905=IEA, GO:0005887=ISS, GO:0016021=IEA, GO:0034185=IPI} aorta morphogenesis, apoptotic cell clearance, beta-amyloid clearance, cholesterol metabolic process, lipoprotein transport, negative regulation of Wnt receptor signaling pathway, negative regulation of platelet-derived growth factor receptor-beta signaling pathway, negative regulation of smooth muscle cell migration, phototransduction, visible light, positive regulation of cholesterol efflux, positive regulation of lipid transport, receptor-mediated endocytosis, regulation of actin cytoskeleton organization, regulation of cholesterol transport, regulation of phospholipase A2 activity, retinoid metabolic process coated pit, endocytic vesicle membrane, integral to membrane, integral to plasma membrane, nucleus, plasma membrane apolipoprotein binding, calcium ion binding, lipoprotein particle receptor binding, lipoprotein transporter activity, protein binding, protein complex binding, receptor activity Human InterPro:IPR001881|InterPro:IPR018097 LRP10 UniProtKB UniProtKB {GO:0006629=GO_REF:0000019, GO:0005041=GO_REF:0000019, GO:0005905=GO_REF:0000039, GO:0048839=GO_REF:0000019, GO:0006869=GO_REF:0000019, GO:0016021=GO_REF:0000019} Q7Z4F1 Low-density lipoprotein receptor-related protein 10 protein 20130413 {GO:0006629=IEA, GO:0005041=IEA, GO:0005905=IEA, GO:0048839=IEA, GO:0006869=IEA, GO:0016021=IEA} inner ear development, lipid metabolic process, lipid transport coated pit, integral to membrane low-density lipoprotein receptor activity Human UniProtKB-SubCell:SL-0072 LRP11 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q86VZ4 Low-density lipoprotein receptor-related protein 11 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 LRP12 IntAct UniProtKB {GO:0005515=PMID:12809483, GO:0005041=PMID:12809483, GO:0007165=PMID:12809483, GO:0005905=GO_REF:0000039, GO:0005887=PMID:12809483, GO:0016021=PMID:9927190, GO:0040008=PMID:9927190, GO:0006897=PMID:12809483} Q9Y561 Low-density lipoprotein receptor-related protein 12 protein 20130415 {GO:0005515=IPI, GO:0005041=NAS, GO:0007165=NAS, GO:0005905=IEA, GO:0005887=IDA, GO:0016021=NAS, GO:0040008=NAS, GO:0006897=NAS} endocytosis, regulation of growth, signal transduction coated pit, integral to membrane, integral to plasma membrane low-density lipoprotein receptor activity, protein binding Human UniProtKB:Q9NPI5 LRP1B PINC UniProtKB {GO:0005041=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0015031=PMID:10766186, GO:0006898=PMID:10766186} Q9NZR2 Low-density lipoprotein receptor-related protein 1B protein 20030904 {GO:0005041=IEA, GO:0005509=IEA, GO:0016021=IEA, GO:0015031=TAS, GO:0006898=TAS} protein transport, receptor-mediated endocytosis integral to membrane calcium ion binding, low-density lipoprotein receptor activity Human LRP2 Reactome UniProtKB {GO:0006629=PMID:7768901, GO:0005515=PMID:14528014, GO:0017124=GO_REF:0000037, GO:0005794=GO_REF:0000019, GO:0007603=Reactome:REACT_160125, GO:0005886=Reactome:REACT_160272, GO:0042359=Reactome:REACT_13523, GO:0005783=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0030139=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0031526=GO_REF:0000019, GO:0001523=Reactome:REACT_24968, GO:0005764=PMID:7768901, GO:0006898=GO_REF:0000019, GO:0006897=PMID:7768901, GO:0016324=GO_REF:0000024, GO:0005905=GO_REF:0000039, GO:0006486=PMID:2786251, GO:0016021=GO_REF:0000037, GO:0030900=GO_REF:0000019, GO:0008202=Reactome:REACT_11057, GO:0005768=GO_REF:0000019} P98164 Low-density lipoprotein receptor-related protein 2 protein 20130301 {GO:0006629=TAS, GO:0005515=IPI, GO:0017124=IEA, GO:0005794=IEA, GO:0007603=TAS, GO:0005886=TAS, GO:0042359=TAS, GO:0005783=IEA, GO:0008283=IEA, GO:0005509=IEA, GO:0030139=IEA, GO:0044281=TAS, GO:0031526=IEA, GO:0001523=TAS, GO:0005764=TAS, GO:0006898=IEA, GO:0006897=TAS, GO:0016324=ISS, GO:0005905=IEA, GO:0006486=TAS, GO:0016021=IEA, GO:0030900=IEA, GO:0008202=TAS, GO:0005768=IEA} cell proliferation, endocytosis, forebrain development, lipid metabolic process, phototransduction, visible light, protein glycosylation, receptor-mediated endocytosis, retinoid metabolic process, small molecule metabolic process, steroid metabolic process, vitamin D metabolic process Golgi apparatus, apical plasma membrane, brush border membrane, coated pit, endocytic vesicle, endoplasmic reticulum, endosome, integral to membrane, lysosome, plasma membrane SH3 domain binding, calcium ion binding, protein binding Human LRP2BP HGNC UniProtKB {GO:0005515=PMID:12508107, GO:0005737=GO_REF:0000039} Q9P2M1 LRP2-binding protein protein 20050222 {GO:0005515=IPI, GO:0005737=IEA} cytoplasm protein binding Human UniProtKB:Q7Z5C0 LRP3 PINC UniProtKB {GO:0005905=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0006898=PMID:9693042} O75074 Low-density lipoprotein receptor-related protein 3 protein 20030904 {GO:0005905=IEA, GO:0016021=IEA, GO:0006898=TAS} receptor-mediated endocytosis coated pit, integral to membrane Human LRP4 BHF-UCL UniProtKB {GO:0005515=PMID:21471202, GO:0030971=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0001822=GO_REF:0000019, GO:0005509=GO_REF:0000029, GO:0009954=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0009953=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0006897=GO_REF:0000037, GO:0030279=PMID:21471202, GO:0043113=GO_REF:0000019, GO:0042475=GO_REF:0000019, GO:0051124=GO_REF:0000019, GO:0001932=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0016055=GO_REF:0000037, GO:0090090=PMID:20093106, GO:0001942=GO_REF:0000019, GO:0042733=GO_REF:0000019} O75096 Low-density lipoprotein receptor-related protein 4 protein 20100914 {GO:0005515=IPI, GO:0030971=IEA, GO:0005886=IEA, GO:0001822=IEA, GO:0005509=NAS, GO:0009954=IEA, GO:0005575=ND, GO:0009953=IEA, GO:0042803=IEA, GO:0006897=IEA, GO:0030279=IMP, GO:0043113=IEA, GO:0042475=IEA, GO:0051124=IEA, GO:0001932=IEA, GO:0016021=IEA, GO:0016055=IEA, GO:0090090=IDA, GO:0001942=IEA, GO:0042733=IEA} Wnt receptor signaling pathway, dorsal/ventral pattern formation, embryonic digit morphogenesis, endocytosis, hair follicle development, kidney development, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of ossification, odontogenesis of dentin-containing tooth, proximal/distal pattern formation, receptor clustering, regulation of protein phosphorylation, synaptic growth at neuromuscular junction cellular_component, integral to membrane, plasma membrane calcium ion binding, protein binding, protein homodimerization activity, receptor tyrosine kinase binding Human LRP5 BHF-UCL UniProtKB {GO:0005515=PMID:18762581, GO:0019534=PMID:18350154, GO:0017147=GO_REF:0000033, GO:0008284=PMID:9790987, GO:0005886=PMID:17680723, GO:0071901=PMID:19107203, GO:0005783=GO_REF:0000039, GO:0060042=PMID:15346351, GO:0030326=GO_REF:0000033, GO:0048539=PMID:17680723, GO:0009952=GO_REF:0000033, GO:0044332=PMID:11029007, GO:0048596=GO_REF:0000033, GO:0046849=GO_REF:0000033, GO:0045944=PMID:12857724, GO:0006007=PMID:19673927, GO:0016055=PMID:17955262, GO:0060070=PMID:15035989, GO:0042813=GO_REF:0000033, GO:0042632=PMID:18721193, GO:0002053=PMID:17680723, GO:0045840=PMID:9790987, GO:0060059=GO_REF:0000033, GO:0015026=GO_REF:0000033, GO:0001702=GO_REF:0000033, GO:0060828=PMID:18044981, GO:0006897=GO_REF:0000037, GO:0043235=PMID:18762581, GO:0061304=PMID:15024691, GO:0045668=PMID:17680723, GO:0002076=GO_REF:0000033, GO:0060349=PMID:20146170, GO:0045600=PMID:17680723, GO:0008217=PMID:18721193, GO:0016021=GO_REF:0000037, GO:0045893=PMID:17955262, GO:0060612=PMID:17680723, GO:0060444=GO_REF:0000033, GO:0061178=GO_REF:0000033} O75197 Low-density lipoprotein receptor-related protein 5 protein 20100930 {GO:0005515=IPI, GO:0019534=IMP, GO:0017147=IBA, GO:0008284=IDA, GO:0005886=IDA, GO:0071901=IMP, GO:0005783=IEA, GO:0060042=IMP, GO:0030326=IBA, GO:0048539=IMP, GO:0009952=IBA, GO:0044332=IDA, GO:0048596=IBA, GO:0046849=IBA, GO:0045944=IDA, GO:0006007=IMP, GO:0016055=IDA, GO:0060070=IDA, GO:0042813=IBA, GO:0042632=IMP, GO:0002053=IMP, GO:0045840=IDA, GO:0060059=IBA, GO:0015026=IBA, GO:0001702=IBA, GO:0060828=IMP, GO:0006897=IEA, GO:0043235=IDA, GO:0061304=IMP, GO:0045668=IMP, GO:0002076=IBA, GO:0060349=IMP, GO:0045600=IMP, GO:0008217=IMP, GO:0016021=IEA, GO:0045893=IDA, GO:0060612=IMP, GO:0060444=IBA, GO:0061178=IBA} Wnt receptor signaling pathway, Wnt receptor signaling pathway involved in dorsal/ventral axis specification, adipose tissue development, anterior/posterior pattern specification, bone marrow development, bone morphogenesis, bone remodeling, branching involved in mammary gland duct morphogenesis, canonical Wnt receptor signaling pathway, cholesterol homeostasis, embryonic camera-type eye morphogenesis, embryonic limb morphogenesis, embryonic retina morphogenesis in camera-type eye, endocytosis, gastrulation with mouth forming second, glucose catabolic process, negative regulation of osteoblast differentiation, negative regulation of protein serine/threonine kinase activity, osteoblast development, positive regulation of cell proliferation, positive regulation of fat cell differentiation, positive regulation of mesenchymal cell proliferation, positive regulation of mitosis, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of blood pressure, regulation of canonical Wnt receptor signaling pathway, regulation of insulin secretion involved in cellular response to glucose stimulus, retina morphogenesis in camera-type eye, retinal blood vessel morphogenesis endoplasmic reticulum, integral to membrane, plasma membrane, receptor complex Wnt-activated receptor activity, Wnt-protein binding, coreceptor activity, protein binding, toxin transporter activity Human LRP5L RefGenome UniProtKB {GO:0042813=GO_REF:0000033, GO:0017147=GO_REF:0000033, GO:0060070=GO_REF:0000033, GO:0044332=GO_REF:0000033} A4QPB2 Low-density lipoprotein receptor-related protein 5-like protein protein 20110720 {GO:0042813=IBA, GO:0017147=IBA, GO:0060070=IBA, GO:0044332=IBA} Wnt receptor signaling pathway involved in dorsal/ventral axis specification, canonical Wnt receptor signaling pathway Wnt-activated receptor activity, Wnt-protein binding Human PANTHER:PTN000056248 LRP6 GOC UniProtKB {GO:0005515=PMID:19107203, GO:0090263=PMID:15271658, GO:0048705=GO_REF:0000019, GO:2000149=GO_REF:0000019, GO:0014029=PMID:11029007, GO:0021861=GO_REF:0000019, GO:0048596=GO_REF:0000033, GO:0005109=PMID:11029007, GO:0042074=GO_REF:0000019, GO:0071397=PMID:16890161, GO:0014033=PMID:11029007, GO:2000151=GO_REF:0000019, GO:0016055=PMID:11029007, GO:0090118=GO_REF:0000033, GO:0009986=PMID:12897152, GO:0021874=GO_REF:0000019, GO:0001702=GO_REF:0000033, GO:0060349=GO_REF:0000033, GO:0060535=GO_REF:0000033, GO:0060444=GO_REF:0000033, GO:0060596=GO_REF:0000019, GO:0021987=GO_REF:0000033, GO:0071901=PMID:19107203, GO:0005783=GO_REF:0000039, GO:0090244=GO_REF:0000033, GO:0044332=PMID:11029007, GO:0044335=PMID:11029007, GO:0090245=GO_REF:0000033, GO:0044340=PMID:15271658, GO:0051091=PMID:14739301, GO:0042475=GO_REF:0000033, GO:0060070=PMID:20137080, GO:0061310=GO_REF:0000019, GO:0042813=GO_REF:0000033, GO:0005102=PMID:14739301, GO:0060059=GO_REF:0000033, GO:0031410=PMID:16890161, GO:0036342=GO_REF:0000019, GO:0003344=GO_REF:0000033, GO:0060325=GO_REF:0000033, GO:0016020=GO_REF:0000019, GO:0034392=PMID:15271658, GO:0005901=PMID:17569865, GO:0035116=GO_REF:0000019, GO:0030901=GO_REF:0000033, GO:0034185=GO_REF:0000033, GO:0035115=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0005769=GO_REF:0000019, GO:0017147=PMID:11029007, GO:0019534=PMID:18350154, GO:0045599=GO_REF:0000019, GO:0045598=GO_REF:0000033, GO:0050680=GO_REF:0000019, GO:0045202=GO_REF:0000033, GO:0042803=PMID:12897152, GO:0005041=PMID:16263759, GO:0001947=GO_REF:0000019, GO:0009880=GO_REF:0000033, GO:0021794=GO_REF:0000033, GO:0021795=GO_REF:0000019, GO:0046849=GO_REF:0000033, GO:0060284=GO_REF:0000019, GO:0043025=GO_REF:0000033, GO:0019210=PMID:16365045, GO:0021587=GO_REF:0000033, GO:0001843=GO_REF:0000033, GO:0045787=PMID:15271658, GO:0051593=GO_REF:0000019, GO:0043235=GO_REF:0000033, GO:0071936=PMID:11029007, GO:0030917=GO_REF:0000033, GO:0061324=GO_REF:0000019, GO:0045893=PMID:18215320, GO:0042733=GO_REF:0000019, GO:2000168=GO_REF:0000019, GO:0005886=PMID:17569865, GO:2000166=GO_REF:0000019, GO:0007268=GO_REF:0000033, GO:0021943=GO_REF:0000019, GO:0030326=GO_REF:0000033, GO:0009952=GO_REF:0000033, GO:0045778=GO_REF:0000019, GO:0009950=GO_REF:0000019, GO:0035261=GO_REF:0000033, GO:0060026=GO_REF:0000033, GO:0030278=GO_REF:0000033, GO:0045780=GO_REF:0000019, GO:0045944=PMID:12857724, GO:0060021=GO_REF:0000033, GO:1901998=PMID:16564009, GO:0043065=GO_REF:0000019, GO:0090009=GO_REF:0000033, GO:2000055=PMID:15908424, GO:0002053=GO_REF:0000019, GO:0071542=GO_REF:0000019, GO:2000162=GO_REF:0000019, GO:0001933=PMID:16365045, GO:2000164=GO_REF:0000019, GO:0006469=PMID:16365045} O75581 Low-density lipoprotein receptor-related protein 6 protein 20130413 {GO:0005515=IPI, GO:0090263=IDA, GO:0048705=IEA, GO:2000149=IEA, GO:0014029=IDA, GO:0021861=IEA, GO:0048596=IBA, GO:0005109=IPI, GO:0042074=IEA, GO:0071397=IMP, GO:0014033=IDA, GO:2000151=IEA, GO:0016055=IMP, GO:0090118=IBA, GO:0009986=IDA, GO:0021874=IEA, GO:0001702=IBA, GO:0060349=IBA, GO:0060535=IBA, GO:0060444=IBA, GO:0060596=IEA, GO:0021987=IBA, GO:0071901=IDA, GO:0005783=IEA, GO:0090244=IBA, GO:0044332=IDA, GO:0044335=IC, GO:0090245=IBA, GO:0044340=IC, GO:0051091=IDA, GO:0042475=IBA, GO:0060070=IDA, GO:0061310=IEA, GO:0042813=IBA, GO:0005102=IPI, GO:0060059=IBA, GO:0031410=IDA, GO:0036342=IEA, GO:0003344=IBA, GO:0060325=IBA, GO:0016020=IEA, GO:0034392=IMP, GO:0005901=IDA, GO:0035116=IEA, GO:0030901=IBA, GO:0034185=IBA, GO:0035115=IEA, GO:0016021=IEA, GO:0005769=IEA, GO:0017147=IPI, GO:0019534=IMP, GO:0045599=IEA, GO:0045598=IBA, GO:0050680=IEA, GO:0045202=IBA, GO:0042803=IPI, GO:0005041=IDA, GO:0001947=IEA, GO:0009880=IBA, GO:0021794=IBA, GO:0021795=IEA, GO:0046849=IBA, GO:0060284=IEA, GO:0043025=IBA, GO:0019210=IMP, GO:0021587=IBA, GO:0001843=IBA, GO:0045787=IMP, GO:0051593=IEA, GO:0043235=IBA, GO:0071936=IDA, GO:0030917=IBA, GO:0061324=IEA, GO:0045893=IMP, GO:0042733=IEA, GO:2000168=IEA, GO:0005886=IDA, GO:2000166=IEA, GO:0007268=IBA, GO:0021943=IEA, GO:0030326=IBA, GO:0009952=IBA, GO:0045778=IEA, GO:0009950=IEA, GO:0035261=IBA, GO:0060026=IBA, GO:0030278=IBA, GO:0045780=IEA, GO:0045944=IDA, GO:0060021=IBA, GO:1901998=IMP, GO:0043065=IEA, GO:0090009=IBA, GO:2000055=IDA, GO:0002053=IEA, GO:0071542=IEA, GO:2000162=IEA, GO:0001933=IMP, GO:2000164=IEA, GO:0006469=IMP} Wnt receptor signaling pathway, Wnt receptor signaling pathway involved in dorsal/ventral axis specification, Wnt receptor signaling pathway involved in forebrain neuroblast division, Wnt receptor signaling pathway involved in somitogenesis, anterior/posterior pattern specification, axis elongation involved in somitogenesis, bone morphogenesis, bone remodeling, branching involved in mammary gland duct morphogenesis, canonical Wnt receptor signaling pathway, canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development, canonical Wnt receptor signaling pathway involved in neural crest cell differentiation, canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation, canonical Wnt receptor signaling pathway involved in regulation of cell proliferation, cell migration involved in gastrulation, cellular response to cholesterol, cerebellum morphogenesis, cerebral cortex cell migration, cerebral cortex development, convergent extension, dopaminergic neuron differentiation, dorsal/ventral axis specification, embryonic camera-type eye morphogenesis, embryonic digit morphogenesis, embryonic forelimb morphogenesis, embryonic hindlimb morphogenesis, embryonic limb morphogenesis, embryonic pattern specification, embryonic retina morphogenesis in camera-type eye, external genitalia morphogenesis, face morphogenesis, forebrain radial glial cell differentiation, formation of radial glial scaffolds, gastrulation with mouth forming second, heart looping, mammary placode formation, midbrain development, midbrain-hindbrain boundary development, negative regulation of epithelial cell proliferation, negative regulation of fat cell differentiation, negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis, negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis, negative regulation of planar cell polarity pathway involved in neural tube closure, negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis, negative regulation of planar cell polarity pathway involved in pericardium morphogenesis, negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis, negative regulation of protein kinase activity, negative regulation of protein phosphorylation, negative regulation of protein serine/threonine kinase activity, negative regulation of smooth muscle cell apoptotic process, neural crest cell differentiation, neural crest formation, neural tube closure, odontogenesis of dentin-containing tooth, palate development, pericardium morphogenesis, positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification, positive regulation of apoptotic process, positive regulation of bone resorption, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of cell cycle, positive regulation of mesenchymal cell proliferation, positive regulation of ossification, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, post-anal tail morphogenesis, primitive streak formation, receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport, regulation of cell development, regulation of fat cell differentiation, regulation of ossification, response to folic acid, skeletal system morphogenesis, synaptic transmission, thalamus development, toxin transport, trachea cartilage morphogenesis caveola, cell surface, cytoplasmic vesicle, early endosome, endoplasmic reticulum, integral to membrane, membrane, neuronal cell body, plasma membrane, receptor complex, synapse Wnt-activated receptor activity, Wnt-protein binding, apolipoprotein binding, coreceptor activity involved in Wnt receptor signaling pathway, frizzled binding, kinase inhibitor activity, low-density lipoprotein receptor activity, protein binding, protein homodimerization activity, receptor binding, toxin transporter activity Human LRP8 BHF-UCL UniProtKB {GO:0006629=PMID:11152697, GO:0005515=PMID:12950167, GO:0005886=Reactome:REACT_160272, GO:0007603=Reactome:REACT_160125, GO:0061098=GO_REF:0000024, GO:0019221=PMID:11152697, GO:0050731=GO_REF:0000024, GO:0030229=PMID:8626535, GO:0006508=PMID:11152697, GO:0061003=GO_REF:0000024, GO:1900006=GO_REF:0000024, GO:0021541=GO_REF:0000024, GO:0005509=GO_REF:0000002, GO:0050804=GO_REF:0000024, GO:0005576=GO_REF:0000039, GO:0000122=GO_REF:0000024, GO:0021819=GO_REF:0000019, GO:0001523=Reactome:REACT_24968, GO:0038026=GO_REF:0000024, GO:0006897=PMID:8626535, GO:0038025=GO_REF:0000024, GO:0007165=PMID:10380922, GO:0032793=GO_REF:0000024, GO:0007596=Reactome:REACT_604, GO:0005901=PMID:11369809, GO:0016021=PMID:11152697, GO:0034185=PMID:8626535, GO:0004888=PMID:8626535} Q14114 Low-density lipoprotein receptor-related protein 8 protein 20120502 {GO:0006629=NAS, GO:0005515=IPI, GO:0005886=TAS, GO:0007603=TAS, GO:0061098=ISS, GO:0019221=NAS, GO:0050731=ISS, GO:0030229=IDA, GO:0006508=NAS, GO:0061003=ISS, GO:1900006=ISS, GO:0021541=ISS, GO:0005509=IEA, GO:0050804=ISS, GO:0005576=IEA, GO:0000122=ISS, GO:0021819=IEA, GO:0001523=TAS, GO:0038026=ISS, GO:0006897=IDA, GO:0038025=ISS, GO:0007165=TAS, GO:0032793=ISS, GO:0007596=TAS, GO:0005901=IDA, GO:0016021=IC, GO:0034185=IC, GO:0004888=TAS} ammon gyrus development, blood coagulation, cytokine-mediated signaling pathway, endocytosis, layer formation in cerebral cortex, lipid metabolic process, negative regulation of transcription from RNA polymerase II promoter, phototransduction, visible light, positive regulation of CREB transcription factor activity, positive regulation of dendrite development, positive regulation of dendritic spine morphogenesis, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of protein tyrosine kinase activity, proteolysis, reelin-mediated signaling pathway, regulation of synaptic transmission, retinoid metabolic process, signal transduction caveola, extracellular region, integral to membrane, plasma membrane apolipoprotein binding, calcium ion binding, protein binding, reelin receptor activity, transmembrane signaling receptor activity, very-low-density lipoprotein particle receptor activity Human UniProtKB:Q924X6 LRPAP1 GOC UniProtKB {GO:0032091=PMID:8083232, GO:0048237=GO_REF:0000019, GO:0009986=GO_REF:0000039, GO:0005886=PMID:16263759, GO:0005783=GO_REF:0000052, GO:0005576=PMID:8083232, GO:0070326=PMID:8083232, GO:0031982=GO_REF:0000019, GO:1900222=PMID:19098903, GO:0010916=PMID:8083232, GO:1900116=PMID:8083232, GO:0006457=PMID:8654360, GO:0004873=PMID:2229028, GO:0016021=PMID:1712782, GO:0051082=PMID:8654360, GO:0035473=GO_REF:0000019, GO:0016192=PMID:8654360, GO:0048019=PMID:8083232, GO:0008201=GO_REF:0000037, GO:0050750=PMID:16263759} P30533 Alpha-2-macroglobulin receptor-associated protein protein 20130413 {GO:0032091=IDA, GO:0048237=IEA, GO:0009986=IEA, GO:0005886=IDA, GO:0005783=IDA, GO:0005576=IDA, GO:0070326=IPI, GO:0031982=IEA, GO:1900222=IGI, GO:0010916=IDA, GO:1900116=IDA, GO:0006457=TAS, GO:0004873=TAS, GO:0016021=TAS, GO:0051082=TAS, GO:0035473=IEA, GO:0016192=TAS, GO:0048019=IDA, GO:0008201=IEA, GO:0050750=IDA} extracellular negative regulation of signal transduction, negative regulation of beta-amyloid clearance, negative regulation of protein binding, negative regulation of very-low-density lipoprotein particle clearance, protein folding, vesicle-mediated transport cell surface, endoplasmic reticulum, extracellular region, integral to membrane, plasma membrane, rough endoplasmic reticulum lumen, vesicle asialoglycoprotein receptor activity, heparin binding, lipase binding, low-density lipoprotein particle receptor binding, receptor antagonist activity, unfolded protein binding, very-low-density lipoprotein particle receptor binding Human LRPPRC HPA UniProtKB {GO:0042645=PMID:18063578, GO:0005515=PMID:15907802, GO:0008017=PMID:12762840, GO:0048471=PMID:12762840, GO:0006355=GO_REF:0000037, GO:0000794=PMID:12762840, GO:0003723=PMID:12832482, GO:0005874=PMID:21525035, GO:0048487=PMID:12762840, GO:0005637=GO_REF:0000039, GO:0005634=PMID:12762840, GO:0006351=GO_REF:0000037, GO:0005739=GO_REF:0000052, GO:0005640=GO_REF:0000039, GO:0051015=PMID:12762840, GO:0047497=PMID:12762840, GO:0003697=GO_REF:0000019, GO:0005654=GO_REF:0000039, GO:0051028=GO_REF:0000037, GO:0005856=PMID:12762840} P42704 Leucine-rich PPR motif-containing protein, mitochondrial protein 20110516 {GO:0042645=IDA, GO:0005515=IPI, GO:0008017=TAS, GO:0048471=IDA, GO:0006355=IEA, GO:0000794=IDA, GO:0003723=NAS, GO:0005874=IDA, GO:0048487=IDA, GO:0005637=IEA, GO:0005634=IDA, GO:0006351=IEA, GO:0005739=IDA, GO:0005640=IEA, GO:0051015=IDA, GO:0047497=TAS, GO:0003697=IEA, GO:0005654=IEA, GO:0051028=IEA, GO:0005856=IDA} mRNA transport, mitochondrion transport along microtubule, regulation of transcription, DNA-dependent, transcription, DNA-dependent condensed nuclear chromosome, cytoskeleton, microtubule, mitochondrial nucleoid, mitochondrion, nuclear inner membrane, nuclear outer membrane, nucleoplasm, nucleus, perinuclear region of cytoplasm RNA binding, actin filament binding, beta-tubulin binding, microtubule binding, protein binding, single-stranded DNA binding Human LRR1 UniPathway UniProtKB {GO:0016567=GO_REF:0000041, GO:0016853=GO_REF:0000038} Q96L50 Leucine-rich repeat protein 1 protein 20130413 {GO:0016567=IEA, GO:0016853=IEA} protein ubiquitination isomerase activity Human UniPathway:UPA00143 LRRC1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0016020=GO_REF:0000039} Q9BTT6 Leucine-rich repeat-containing protein 1 protein 20130413 {GO:0005737=IEA, GO:0016020=IEA} cytoplasm, membrane Human UniProtKB-SubCell:SL-0162 LRRC14 null null {} null null null null {} null null null LRRC15 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8TF66 Leucine-rich repeat-containing protein 15 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 LRRC16A HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0016477=PMID:19846667, GO:0007596=Reactome:REACT_604, GO:0030032=PMID:19846667, GO:0005634=GO_REF:0000052, GO:0007015=PMID:19846667, GO:0046415=PMID:19503597, GO:0030027=PMID:19846667, GO:0031529=PMID:19846667, GO:0005829=Reactome:REACT_25319} Q5VZK9 Leucine-rich repeat-containing protein 16A protein 20111111 {GO:0005737=IDA, GO:0016477=IMP, GO:0007596=TAS, GO:0030032=IMP, GO:0005634=IDA, GO:0007015=NAS, GO:0046415=IMP, GO:0030027=IDA, GO:0031529=IMP, GO:0005829=TAS} actin filament organization, blood coagulation, cell migration, lamellipodium assembly, ruffle organization, urate metabolic process cytoplasm, cytosol, lamellipodium, nucleus Human LRRC18 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q8N456 Leucine-rich repeat-containing protein 18 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 LRRC20 null null {} null null null null {} null null null LRRC23 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q53EV4 Leucine-rich repeat-containing protein 23 protein 20061214 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human LRRC25 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8N386 Leucine-rich repeat-containing protein 25 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 LRRC28 null null {} null null null null {} null null null LRRC3 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0016021=GO_REF:0000037} Q9BY71 Leucine-rich repeat-containing protein 3 protein 20130415 {GO:0005515=IPI, GO:0016021=IEA} integral to membrane protein binding Human UniProtKB:P16333 LRRC32 PINC UniProtKB {GO:0010628=GO_REF:0000019, GO:0005887=PMID:8180135, GO:0046007=GO_REF:0000019, GO:0050710=GO_REF:0000019} Q14392 Leucine-rich repeat-containing protein 32 protein 20030904 {GO:0010628=IEA, GO:0005887=TAS, GO:0046007=IEA, GO:0050710=IEA} negative regulation of activated T cell proliferation, negative regulation of cytokine secretion, positive regulation of gene expression integral to plasma membrane Human LRRC33 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q86YC3 Leucine-rich repeat-containing protein 33 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 LRRC37A UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} A6NMS7 Leucine-rich repeat-containing protein 37A protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 LRRC37B HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0016021=GO_REF:0000037} Q96QE4 Leucine-rich repeat-containing protein 37B protein 20090616 {GO:0005737=IDA, GO:0016021=IEA} cytoplasm, integral to membrane Human LRRC3B UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q96PB8 Leucine-rich repeat-containing protein 3B protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 LRRC4 UniProtKB UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000037, GO:0045211=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q9HBW1 Leucine-rich repeat-containing protein 4 protein 20130413 {GO:0030054=IEA, GO:0005886=IEA, GO:0045211=IEA, GO:0016021=IEA} cell junction, integral to membrane, plasma membrane, postsynaptic membrane Human UniProtKB-SubCell:SL-0219 LRRC40 null null {} null null null null {} null null null LRRC41 UniPathway UniProtKB {GO:0016567=GO_REF:0000041} Q15345 Leucine-rich repeat-containing protein 41 protein 20130413 {GO:0016567=IEA} protein ubiquitination Human UniPathway:UPA00143 LRRC42 null null {} null null null null {} null null null LRRC45 UniProtKB UniProtKB {GO:0005813=PMID:21399614} Q96CN5 Leucine-rich repeat-containing protein 45 protein 20110517 {GO:0005813=IDA} centrosome Human LRRC47 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0003723=GO_REF:0000002, GO:0004826=GO_REF:0000002} Q8N1G4 Leucine-rich repeat-containing protein 47 protein 20130415 {GO:0005515=IPI, GO:0003723=IEA, GO:0004826=IEA} RNA binding, phenylalanine-tRNA ligase activity, protein binding Human UniProtKB:P04591:PRO_0000038596 LRRC49 UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0005874=GO_REF:0000037} Q8IUZ0 Leucine-rich repeat-containing protein 49 protein 20130413 {GO:0005737=IEA, GO:0005874=IEA} cytoplasm, microtubule Human UniProtKB-KW:KW-0493 LRRC4C UniProtKB UniProtKB {GO:0005515=PMID:14595443, GO:0030054=GO_REF:0000037, GO:0016020=PMID:14595443, GO:0005886=GO_REF:0000037, GO:0045211=GO_REF:0000039, GO:0016021=PMID:14595443, GO:0050770=PMID:14595443} Q9HCJ2 Leucine-rich repeat-containing protein 4C protein 20050218 {GO:0005515=IPI, GO:0030054=IEA, GO:0016020=IDA, GO:0005886=IEA, GO:0045211=IEA, GO:0016021=NAS, GO:0050770=IDA} regulation of axonogenesis cell junction, integral to membrane, membrane, plasma membrane, postsynaptic membrane protein binding Human UniProtKB:Q9Y2I2 LRRC57 null null {} null null null null {} null null null LRRC58 null null {} null null null null {} null null null LRRC59 HPA UniProtKB {GO:0042645=PMID:18063578, GO:0005783=GO_REF:0000052, GO:0005789=GO_REF:0000039, GO:0005635=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q96AG4 Leucine-rich repeat-containing protein 59 protein 20101115 {GO:0042645=IDA, GO:0005783=IDA, GO:0005789=IEA, GO:0005635=IEA, GO:0016021=IEA} endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, mitochondrial nucleoid, nuclear envelope Human LRRC61 null null {} null null null null {} null null null LRRC69 null null {} null null null null {} null null null LRRC7 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000037, GO:0045211=GO_REF:0000037, GO:0014069=GO_REF:0000039} Q96NW7 Leucine-rich repeat-containing protein 7 protein 20130413 {GO:0005737=IEA, GO:0030054=IEA, GO:0005886=IEA, GO:0045211=IEA, GO:0014069=IEA} cell junction, cytoplasm, plasma membrane, postsynaptic density, postsynaptic membrane Human UniProtKB-SubCell:SL-0297 LRRC70 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q7Z2Q7 Leucine-rich repeat-containing protein 70 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 LRRC8A UniProtKB UniProtKB {GO:0002329=GO_REF:0000024, GO:0016021=GO_REF:0000037} Q8IWT6 Leucine-rich repeat-containing protein 8A protein 20090925 {GO:0002329=ISS, GO:0016021=IEA} pre-B cell differentiation integral to membrane Human UniProtKB:Q80WG5 LRRC8C UniProtKB UniProtKB {GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q8TDW0 Leucine-rich repeat-containing protein 8C protein 20130413 {GO:0005789=IEA, GO:0016021=IEA} endoplasmic reticulum membrane, integral to membrane Human UniProtKB-SubCell:SL-0097 LRRC8D UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q7L1W4 Leucine-rich repeat-containing protein 8D protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 LRRC8E UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q6NSJ5 Leucine-rich repeat-containing protein 8E protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 LRRCC1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005813=PMID:21399614, GO:0007067=GO_REF:0000037, GO:0005814=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0051301=GO_REF:0000037} Q9C099 Leucine-rich repeat and coiled-coil domain-containing protein 1 protein 20090616 {GO:0005737=IDA, GO:0005813=IDA, GO:0007067=IEA, GO:0005814=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0051301=IEA} cell division, mitosis centriole, centrosome, cytoplasm, nucleolus, nucleus Human LRRFIP1 IntAct UniProtKB {GO:0005515=PMID:10366446, GO:0003725=PMID:9671805, GO:0005737=GO_REF:0000039, GO:0006357=PMID:9705290, GO:0005634=PMID:9705290, GO:0005856=PMID:9671805, GO:0045892=PMID:9705290, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q32MZ4 Leucine-rich repeat flightless-interacting protein 1 protein 20130415 {GO:0005515=IPI, GO:0003725=TAS, GO:0005737=IEA, GO:0006357=TAS, GO:0005634=NAS, GO:0005856=TAS, GO:0045892=NAS, GO:0003677=IEA, GO:0006351=IEA} negative regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, cytoskeleton, nucleus DNA binding, double-stranded RNA binding, protein binding Human UniProtKB:Q13045 LRRFIP2 IntAct UniProtKB {GO:0005515=PMID:15677333, GO:0008150=GO_REF:0000015, GO:0030275=PMID:10366446, GO:0005575=GO_REF:0000015, GO:0016055=GO_REF:0000037} Q9Y608 Leucine-rich repeat flightless-interacting protein 2 protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0030275=IPI, GO:0005575=ND, GO:0016055=IEA} Wnt receptor signaling pathway, biological_process cellular_component LRR domain binding, protein binding Human UniProtKB:Q92997 LRRIQ1 null null {} null null null null {} null null null LRRK1 HPA UniProtKB {GO:0005515=PMID:20144646, GO:0005622=GO_REF:0000002, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000037, GO:0007264=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0042802=PMID:22952686} Q38SD2 Leucine-rich repeat serine/threonine-protein kinase 1 protein 20101115 {GO:0005515=IPI, GO:0005622=IEA, GO:0005739=IDA, GO:0005737=IDA, GO:0004672=IEA, GO:0004674=IEA, GO:0007264=IEA, GO:0005525=IEA, GO:0005524=IEA, GO:0046872=IEA, GO:0042802=IPI} small GTPase mediated signal transduction cytoplasm, intracellular, mitochondrion ATP binding, GTP binding, identical protein binding, metal ion binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human LRRK2 GOC UniProtKB {GO:0005802=GO_REF:0000019, GO:0005515=PMID:21048939, GO:0042803=PMID:16321986, GO:0007406=PMID:21168496, GO:0022028=PMID:21168496, GO:0043068=PMID:17200152, GO:0046777=PMID:17200152, GO:0018105=PMID:19576176, GO:0000165=PMID:17200152, GO:0018107=PMID:21048939, GO:0031398=PMID:16352719, GO:0043025=PMID:21696411, GO:0010942=PMID:21168496, GO:0006979=PMID:19692353, GO:0061002=PMID:21168496, GO:0004708=PMID:19302196, GO:0035640=PMID:20659558, GO:0034260=PMID:22423108, GO:0048312=PMID:21159966, GO:0044325=PMID:22012985, GO:0043547=PMID:17442267, GO:0006184=PMID:21048939, GO:0070997=PMID:19692353, GO:0045121=GO_REF:0000019, GO:0010508=GO_REF:0000024, GO:0032473=PMID:16269541, GO:0043005=PMID:21048939, GO:0005886=GO_REF:0000019, GO:0007264=GO_REF:0000002, GO:0032436=GO_REF:0000024, GO:0003924=PMID:21048939, GO:0032839=PMID:21696411, GO:0035564=GO_REF:0000024, GO:0008340=PMID:19692353, GO:0005739=PMID:21850687, GO:0000187=PMID:19302196, GO:0040012=PMID:19692353, GO:0005737=PMID:16321986, GO:0000186=PMID:19302196, GO:0021772=PMID:21168496, GO:0015631=PMID:21159966, GO:0007528=PMID:21159966, GO:0042391=PMID:21159966, GO:2000173=PMID:21168496, GO:0060161=PMID:20659558, GO:0006914=GO_REF:0000037, GO:0014043=PMID:21168496, GO:0005525=PMID:17260967, GO:0005524=GO_REF:0000037, GO:0008021=GO_REF:0000019, GO:0004672=PMID:21850687, GO:0004674=PMID:21048939, GO:0034211=PMID:17260967, GO:0001934=PMID:20659558, GO:0017048=PMID:21048939, GO:0005096=PMID:17442267} Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 protein 20130413 {GO:0005802=IEA, GO:0005515=IPI, GO:0042803=IPI, GO:0007406=IMP, GO:0022028=IMP, GO:0043068=IDA, GO:0046777=IDA, GO:0018105=IDA, GO:0000165=IDA, GO:0018107=IDA, GO:0031398=IDA, GO:0043025=IDA, GO:0010942=IMP, GO:0006979=IMP, GO:0061002=IMP, GO:0004708=IDA, GO:0035640=IMP, GO:0034260=IDA, GO:0048312=IMP, GO:0044325=IPI, GO:0043547=IDA, GO:0006184=IDA, GO:0070997=IMP, GO:0045121=IEA, GO:0010508=ISS, GO:0032473=IDA, GO:0043005=IDA, GO:0005886=IEA, GO:0007264=IEA, GO:0032436=ISS, GO:0003924=IDA, GO:0032839=IDA, GO:0035564=ISS, GO:0008340=IMP, GO:0005739=IDA, GO:0000187=IDA, GO:0040012=IMP, GO:0005737=IDA, GO:0000186=IDA, GO:0021772=IMP, GO:0015631=IDA, GO:0007528=IMP, GO:0042391=IMP, GO:2000173=IMP, GO:0060161=IMP, GO:0006914=IEA, GO:0014043=IMP, GO:0005525=IDA, GO:0005524=IEA, GO:0008021=IEA, GO:0004672=IDA, GO:0004674=IDA, GO:0034211=IDA, GO:0001934=IMP, GO:0017048=IPI, GO:0005096=IDA} GTP catabolic process, MAPK cascade, activation of MAPK activity, activation of MAPKK activity, autophagy, determination of adult lifespan, exploration behavior, intracellular distribution of mitochondria, negative regulation of GTPase activity, negative regulation of branching morphogenesis of a nerve, negative regulation of dendritic spine morphogenesis, negative regulation of neuroblast proliferation, negative regulation of neuron maturation, neuromuscular junction development, neuron death, olfactory bulb development, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, positive regulation of GTPase activity, positive regulation of autophagy, positive regulation of cell death, positive regulation of dopamine receptor signaling pathway, positive regulation of programmed cell death, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of protein phosphorylation, positive regulation of protein ubiquitination, protein autophosphorylation, regulation of kidney size, regulation of locomotion, regulation of membrane potential, response to oxidative stress, small GTPase mediated signal transduction, tangential migration from the subventricular zone to the olfactory bulb cytoplasm, dendrite cytoplasm, external side of mitochondrial outer membrane, membrane raft, mitochondrion, neuron projection, neuronal cell body, plasma membrane, synaptic vesicle, trans-Golgi network ATP binding, GTP binding, GTP-dependent protein kinase activity, GTPase activator activity, GTPase activity, MAP kinase kinase activity, Rho GTPase binding, ion channel binding, protein binding, protein homodimerization activity, protein kinase activity, protein serine/threonine kinase activity, tubulin binding Human LRRN1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q6UXK5 Leucine-rich repeat neuronal protein 1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 LRRN2 PINC UniProtKB {GO:0007165=PMID:9662332, GO:0004872=PMID:9662332, GO:0016021=GO_REF:0000037, GO:0007155=PMID:9662332} O75325 Leucine-rich repeat neuronal protein 2 protein 20030904 {GO:0007165=TAS, GO:0004872=TAS, GO:0016021=IEA, GO:0007155=TAS} cell adhesion, signal transduction integral to membrane receptor activity Human LRRN4 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8WUT4 Leucine-rich repeat neuronal protein 4 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 LRRTM4 UniProtKB UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0045211=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q86VH4 Leucine-rich repeat transmembrane neuronal protein 4 protein 20130413 {GO:0030054=IEA, GO:0005886=IEA, GO:0045211=IEA, GO:0016021=IEA} cell junction, integral to membrane, plasma membrane, postsynaptic membrane Human UniProtKB-SubCell:SL-0219 LRSAM1 HPA UniProtKB {GO:0005515=PMID:15256501, GO:0000209=PMID:18077552, GO:0004842=PMID:15256501, GO:0070086=PMID:15256501, GO:0005576=GO_REF:0000002, GO:0015031=GO_REF:0000037, GO:0046755=PMID:15256501, GO:0051865=PMID:15256501, GO:0030163=PMID:18077552, GO:0005737=GO_REF:0000052, GO:0005179=GO_REF:0000002, GO:0045806=PMID:15256501, GO:0008270=GO_REF:0000002, GO:0044425=PMID:15256501} Q6UWE0 E3 ubiquitin-protein ligase LRSAM1 protein 20100326 {GO:0005515=IPI, GO:0000209=IDA, GO:0004842=IDA, GO:0070086=IDA, GO:0005576=IEA, GO:0015031=IEA, GO:0046755=IMP, GO:0051865=IDA, GO:0030163=IMP, GO:0005737=IDA, GO:0005179=IEA, GO:0045806=IMP, GO:0008270=IEA, GO:0044425=IDA} negative regulation of endocytosis, non-lytic virus budding, protein autoubiquitination, protein catabolic process, protein polyubiquitination, protein transport, ubiquitin-dependent endocytosis cytoplasm, extracellular region, membrane part hormone activity, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human LRTOMT UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0016206=PMID:18794526, GO:0007605=PMID:18794526, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037, GO:0042135=GO_REF:0000037, GO:0042424=PMID:18794526, GO:0060117=PMID:18794526} Q96E66 Leucine-rich repeat-containing protein 51 protein 20130413 {GO:0005737=IEA, GO:0016206=ISS, GO:0007605=ISS, GO:0005575=ND, GO:0016021=IEA, GO:0042135=IEA, GO:0042424=ISS, GO:0060117=ISS} auditory receptor cell development, catecholamine catabolic process, neurotransmitter catabolic process, sensory perception of sound cellular_component, cytoplasm, integral to membrane catechol O-methyltransferase activity Human UniProtKB-SubCell:SL-0086 LRWD1 UniProtKB UniProtKB {GO:0005515=PMID:20932478, GO:0008327=PMID:21029866, GO:0006325=PMID:20932478, GO:0005634=PMID:21029866, GO:0035064=PMID:21029866, GO:0005721=PMID:20932478, GO:0071169=PMID:20932478, GO:0006270=PMID:20932478, GO:0003682=PMID:21029866, GO:0031933=PMID:20932478, GO:0005664=PMID:21029866, GO:0000080=PMID:20932478, GO:0016568=GO_REF:0000037} Q9UFC0 Leucine-rich repeat and WD repeat-containing protein 1 protein 20101105 {GO:0005515=IPI, GO:0008327=IDA, GO:0006325=IMP, GO:0005634=IDA, GO:0035064=IDA, GO:0005721=IDA, GO:0071169=IDA, GO:0006270=TAS, GO:0003682=IDA, GO:0031933=IDA, GO:0005664=IDA, GO:0000080=IMP, GO:0016568=IEA} DNA replication initiation, G1 phase of mitotic cell cycle, chromatin modification, chromatin organization, establishment of protein localization to chromatin centromeric heterochromatin, nuclear origin of replication recognition complex, nucleus, telomeric heterochromatin chromatin binding, methyl-CpG binding, methylated histone residue binding, protein binding Human LSAMP IntAct UniProtKB {GO:0005515=PMID:21982860, GO:0005886=GO_REF:0000039, GO:0031225=GO_REF:0000037, GO:0007155=GO_REF:0000037, GO:0007399=PMID:8666243} Q13449 Limbic system-associated membrane protein protein 20130415 {GO:0005515=IPI, GO:0005886=IEA, GO:0031225=IEA, GO:0007155=IEA, GO:0007399=TAS} cell adhesion, nervous system development anchored to membrane, plasma membrane protein binding Human UniProtKB:Q9P121 LSG1 GOC UniProtKB {GO:0006184=GO_REF:0000033, GO:0005737=GO_REF:0000052, GO:0015030=PMID:16209721, GO:0005783=GO_REF:0000054, GO:0042254=GO_REF:0000033, GO:0003924=GO_REF:0000033, GO:0005634=GO_REF:0000052, GO:0015031=GO_REF:0000037, GO:0005525=PMID:16209721, GO:0051168=PMID:16209721, GO:0005829=GO_REF:0000033} Q9H089 Large subunit GTPase 1 homolog protein 20130413 {GO:0006184=IBA, GO:0005737=IDA, GO:0015030=IDA, GO:0005783=IDA, GO:0042254=IBA, GO:0003924=IBA, GO:0005634=IDA, GO:0015031=IEA, GO:0005525=IDA, GO:0051168=IDA, GO:0005829=IBA} GTP catabolic process, nuclear export, protein transport, ribosome biogenesis Cajal body, cytoplasm, cytosol, endoplasmic reticulum, nucleus GTP binding, GTPase activity Human PANTHER:PTN000119716 LSM1 IntAct UniProtKB {GO:0006397=GO_REF:0000037, GO:0005515=PMID:15231747, GO:0008380=PMID:10369684, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=GO_REF:0000037, GO:0043928=Reactome:REACT_20518, GO:0005634=PMID:18559850, GO:0005829=Reactome:REACT_20560, GO:0005737=PMID:18559850, GO:0030529=GO_REF:0000037, GO:0000375=PMID:10369684, GO:0071044=PMID:18172165, GO:0000288=Reactome:REACT_20639} O15116 U6 snRNA-associated Sm-like protein LSm1 protein 20130415 {GO:0006397=IEA, GO:0005515=IPI, GO:0008380=TAS, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=IEA, GO:0043928=TAS, GO:0005634=IDA, GO:0005829=TAS, GO:0005737=IDA, GO:0030529=IEA, GO:0000375=TAS, GO:0071044=IMP, GO:0000288=TAS} RNA metabolic process, RNA splicing, RNA splicing, via transesterification reactions, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, histone mRNA catabolic process, mRNA metabolic process, mRNA processing, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay cytoplasm, cytosol, nucleus, ribonucleoprotein complex RNA binding, protein binding Human UniProtKB:Q9Y333 LSM10 IntAct UniProtKB {GO:0000084=PMID:16914750, GO:0005515=PMID:19060904, GO:0008380=GO_REF:0000037, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0015030=PMID:11574479, GO:0008334=Reactome:REACT_1364, GO:0006366=Reactome:REACT_1366, GO:0031124=Reactome:REACT_1768, GO:0005683=PMID:11574479, GO:0005654=Reactome:REACT_1591, GO:0071208=GO_REF:0000024} Q969L4 U7 snRNA-associated Sm-like protein LSm10 protein 20130415 {GO:0000084=IMP, GO:0005515=IPI, GO:0008380=IEA, GO:0010467=TAS, GO:0006369=TAS, GO:0015030=IDA, GO:0008334=TAS, GO:0006366=TAS, GO:0031124=TAS, GO:0005683=IDA, GO:0005654=TAS, GO:0071208=ISS} RNA splicing, S phase of mitotic cell cycle, gene expression, histone mRNA metabolic process, mRNA 3'-end processing, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter Cajal body, U7 snRNP, nucleoplasm histone pre-mRNA DCP binding, protein binding Human UniProtKB:P62310 LSM11 HPA UniProtKB {GO:0005515=PMID:12975319, GO:0006369=Reactome:REACT_894, GO:0010467=Reactome:REACT_71, GO:0006398=GO_REF:0000024, GO:0006366=Reactome:REACT_1366, GO:0008334=Reactome:REACT_1364, GO:0031124=Reactome:REACT_1768, GO:0005634=GO_REF:0000052, GO:0000084=PMID:16914750, GO:0005683=GO_REF:0000024, GO:0005654=Reactome:REACT_1591, GO:0071204=GO_REF:0000024, GO:0071209=PMID:12975319} P83369 U7 snRNA-associated Sm-like protein LSm11 protein 20110516 {GO:0005515=IPI, GO:0006369=TAS, GO:0010467=TAS, GO:0006398=ISS, GO:0006366=TAS, GO:0008334=TAS, GO:0031124=TAS, GO:0005634=IDA, GO:0000084=IMP, GO:0005683=ISS, GO:0005654=TAS, GO:0071204=ISS, GO:0071209=IDA} S phase of mitotic cell cycle, gene expression, histone mRNA 3'-end processing, histone mRNA metabolic process, mRNA 3'-end processing, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter U7 snRNP, histone pre-mRNA 3'end processing complex, nucleoplasm, nucleus U7 snRNA binding, protein binding Human LSM12 null null {} null null null null {} null null null LSM14A HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0033962=PMID:17074753, GO:0000932=PMID:16484376, GO:0010494=PMID:16484376, GO:0007275=GO_REF:0000037, GO:0006417=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q8ND56 Protein LSM14 homolog A protein 20110516 {GO:0005737=IDA, GO:0033962=IMP, GO:0000932=IDA, GO:0010494=IDA, GO:0007275=IEA, GO:0006417=IEA, GO:0043231=IDA} cytoplasmic mRNA processing body assembly, multicellular organismal development, regulation of translation cytoplasm, cytoplasmic mRNA processing body, cytoplasmic stress granule, intracellular membrane-bounded organelle Human LSM14B UniProtKB UniProtKB {GO:0030529=GO_REF:0000037, GO:0007275=GO_REF:0000037, GO:0006417=GO_REF:0000037} Q9BX40 Protein LSM14 homolog B protein 20130413 {GO:0030529=IEA, GO:0007275=IEA, GO:0006417=IEA} multicellular organismal development, regulation of translation ribonucleoprotein complex Human UniProtKB-KW:KW-0687 LSM2 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0019901=GO_REF:0000019, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0043928=Reactome:REACT_20518, GO:0005634=GO_REF:0000029, GO:0071013=PMID:11991638, GO:0005829=Reactome:REACT_20560, GO:0000398=Reactome:REACT_1753, GO:0005654=Reactome:REACT_2241, GO:0017070=PMID:10523320, GO:0000288=Reactome:REACT_20639} Q9Y333 U6 snRNA-associated Sm-like protein LSm2 protein 20130415 {GO:0005515=IPI, GO:0008380=TAS, GO:0010467=TAS, GO:0019901=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0043928=TAS, GO:0005634=NAS, GO:0071013=IDA, GO:0005829=TAS, GO:0000398=TAS, GO:0005654=TAS, GO:0017070=NAS, GO:0000288=TAS} RNA metabolic process, RNA splicing, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, mRNA metabolic process, mRNA splicing, via spliceosome, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay catalytic step 2 spliceosome, cytosol, nucleoplasm, nucleus U6 snRNA binding, protein binding, protein kinase binding Human UniProtKB:P62310 LSM3 IntAct UniProtKB {GO:0005515=PMID:15231747, GO:0006397=PMID:10369684, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0000398=PMID:11991638, GO:0003723=GO_REF:0000037, GO:0043928=Reactome:REACT_20518, GO:0005634=PMID:10369684, GO:0071013=PMID:11991638, GO:0005829=Reactome:REACT_20560, GO:0000288=Reactome:REACT_20639} P62310 U6 snRNA-associated Sm-like protein LSm3 protein 20130415 {GO:0005515=IPI, GO:0006397=TAS, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0000398=IC, GO:0003723=IEA, GO:0043928=TAS, GO:0005634=TAS, GO:0071013=IDA, GO:0005829=TAS, GO:0000288=TAS} RNA metabolic process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, mRNA metabolic process, mRNA processing, mRNA splicing, via spliceosome, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay catalytic step 2 spliceosome, cytosol, nucleus RNA binding, protein binding Human UniProtKB:O15116 LSM4 IntAct UniProtKB {GO:0006397=GO_REF:0000037, GO:0008380=GO_REF:0000037, GO:0005515=PMID:21988832, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=GO_REF:0000037, GO:0043928=Reactome:REACT_20518, GO:0005829=Reactome:REACT_20560, GO:0030532=PMID:10369684, GO:0005681=GO_REF:0000037, GO:0005688=PMID:10369684, GO:0000288=Reactome:REACT_20639} Q9Y4Z0 U6 snRNA-associated Sm-like protein LSm4 protein 20130415 {GO:0006397=IEA, GO:0008380=IEA, GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=IEA, GO:0043928=TAS, GO:0005829=TAS, GO:0030532=TAS, GO:0005681=IEA, GO:0005688=TAS, GO:0000288=TAS} RNA metabolic process, RNA splicing, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, mRNA metabolic process, mRNA processing, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay U6 snRNP, cytosol, small nuclear ribonucleoprotein complex, spliceosomal complex RNA binding, protein binding Human UniProtKB:Q9UK45 LSM5 IntAct UniProtKB {GO:0005515=PMID:15231747, GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=GO_REF:0000037, GO:0043928=Reactome:REACT_20518, GO:0005634=PMID:10369684, GO:0005681=GO_REF:0000037, GO:0005829=Reactome:REACT_20560, GO:0000288=Reactome:REACT_20639} Q9Y4Y9 U6 snRNA-associated Sm-like protein LSm5 protein 20130415 {GO:0005515=IPI, GO:0008380=IEA, GO:0006397=IEA, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=IEA, GO:0043928=TAS, GO:0005634=TAS, GO:0005681=IEA, GO:0005829=TAS, GO:0000288=TAS} RNA metabolic process, RNA splicing, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, mRNA metabolic process, mRNA processing, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay cytosol, nucleus, spliceosomal complex RNA binding, protein binding Human UniProtKB:Q9UK45 LSM6 IntAct UniProtKB {GO:0005515=PMID:15231747, GO:0006397=GO_REF:0000037, GO:0008380=PMID:10523320, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=GO_REF:0000037, GO:0006364=GO_REF:0000037, GO:0043928=Reactome:REACT_20518, GO:0008033=GO_REF:0000037, GO:0005829=Reactome:REACT_20560, GO:0030532=PMID:10523320, GO:0005681=GO_REF:0000037, GO:0000288=Reactome:REACT_20639} P62312 U6 snRNA-associated Sm-like protein LSm6 protein 20130415 {GO:0005515=IPI, GO:0006397=IEA, GO:0008380=TAS, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=IEA, GO:0006364=IEA, GO:0043928=TAS, GO:0008033=IEA, GO:0005829=TAS, GO:0030532=TAS, GO:0005681=IEA, GO:0000288=TAS} RNA metabolic process, RNA splicing, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, mRNA metabolic process, mRNA processing, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, rRNA processing, tRNA processing cytosol, small nuclear ribonucleoprotein complex, spliceosomal complex RNA binding, protein binding Human UniProtKB:Q9Y4Y9 LSM7 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0000398=GO_REF:0000029, GO:0043928=Reactome:REACT_20518, GO:0005634=GO_REF:0000029, GO:0005681=GO_REF:0000037, GO:0017070=PMID:10523320, GO:0005829=Reactome:REACT_20560, GO:0000288=Reactome:REACT_20639} Q9UK45 U6 snRNA-associated Sm-like protein LSm7 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0000398=NAS, GO:0043928=TAS, GO:0005634=NAS, GO:0005681=IEA, GO:0017070=NAS, GO:0005829=TAS, GO:0000288=TAS} RNA metabolic process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, mRNA metabolic process, mRNA splicing, via spliceosome, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay cytosol, nucleus, spliceosomal complex U6 snRNA binding, protein binding Human UniProtKB:Q9Y4Z0 LSMD1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039} Q9BRA0 LSM domain-containing protein 1 protein 20130413 {GO:0005737=IEA, GO:0005634=IEA} cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 LSP1 PINC UniProtKB {GO:0006968=PMID:2174784, GO:0005886=GO_REF:0000039, GO:0006928=PMID:8274738, GO:0003779=PMID:8274738, GO:0004871=GO_REF:0000002, GO:0015629=PMID:8274738} P33241 Lymphocyte-specific protein 1 protein 20030904 {GO:0006968=TAS, GO:0005886=IEA, GO:0006928=TAS, GO:0003779=TAS, GO:0004871=IEA, GO:0015629=TAS} cellular component movement, cellular defense response actin cytoskeleton, plasma membrane actin binding, signal transducer activity Human LSR HGNC UniProtKB {GO:0001889=GO_REF:0000024, GO:0034361=GO_REF:0000037, GO:0005886=GO_REF:0000024, GO:0034362=GO_REF:0000037, GO:0042627=GO_REF:0000037, GO:0009790=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0019216=GO_REF:0000019} Q86X29 Lipolysis-stimulated lipoprotein receptor protein 20061120 {GO:0001889=ISS, GO:0034361=IEA, GO:0005886=ISS, GO:0034362=IEA, GO:0042627=IEA, GO:0009790=ISS, GO:0016021=IEA, GO:0019216=IEA} embryo development, liver development, regulation of lipid metabolic process chylomicron, integral to membrane, low-density lipoprotein particle, plasma membrane, very-low-density lipoprotein particle Human UniProtKB:Q99KG5 LSS BHF-UCL UniProtKB {GO:0006695=PMID:17186944, GO:0005789=Reactome:REACT_147844, GO:0000250=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0008202=PMID:7639730} P48449 Lanosterol synthase protein 20090126 {GO:0006695=IMP, GO:0005789=TAS, GO:0000250=IEA, GO:0044281=TAS, GO:0003824=IEA, GO:0008202=TAS} cholesterol biosynthetic process, small molecule metabolic process, steroid metabolic process endoplasmic reticulum membrane catalytic activity, lanosterol synthase activity Human LST1 InterPro UniProtKB {GO:0000902=GO_REF:0000002, GO:0005737=PMID:11478849, GO:0006955=GO_REF:0000002, GO:0005794=PMID:11478849, GO:0000139=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0008360=GO_REF:0000037, GO:0016021=PMID:10706707, GO:0009653=PMID:10944527, GO:0016358=PMID:11478849, GO:0050672=PMID:10706707} Q5STA8 Leukocyte-specific transcript 1 protein protein 20130413 {GO:0000902=IEA, GO:0005737=IDA, GO:0006955=IEA, GO:0005794=NAS, GO:0000139=IEA, GO:0016020=IEA, GO:0008360=IEA, GO:0016021=IDA, GO:0009653=NAS, GO:0016358=IDA, GO:0050672=IDA} anatomical structure morphogenesis, cell morphogenesis, dendrite development, immune response, negative regulation of lymphocyte proliferation, regulation of cell shape Golgi apparatus, Golgi membrane, cytoplasm, integral to membrane, membrane Human InterPro:IPR007775 LTA PINC UniProtKB {GO:0032729=GO_REF:0000019, GO:0005164=GO_REF:0000002, GO:0001666=GO_REF:0000019, GO:0002876=GO_REF:0000019, GO:0050830=GO_REF:0000019, GO:0007584=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0005102=PMID:3001529, GO:0007267=PMID:6334807, GO:0048147=GO_REF:0000019, GO:0006917=PMID:6334807, GO:0005125=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0048535=GO_REF:0000019, GO:0007165=PMID:6334807, GO:0002925=GO_REF:0000019, GO:0016020=GO_REF:0000039, GO:0006959=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0044130=GO_REF:0000019} P01374 Lymphotoxin-alpha protein 20030904 {GO:0032729=IEA, GO:0005164=IEA, GO:0001666=IEA, GO:0002876=IEA, GO:0050830=IEA, GO:0007584=IEA, GO:0042493=IEA, GO:0005102=TAS, GO:0007267=TAS, GO:0048147=IEA, GO:0006917=TAS, GO:0005125=IEA, GO:0005615=IEA, GO:0048535=IEA, GO:0007165=TAS, GO:0002925=IEA, GO:0016020=IEA, GO:0006959=IEA, GO:0032496=IEA, GO:0044130=IEA} cell-cell signaling, defense response to Gram-positive bacterium, humoral immune response, induction of apoptosis, lymph node development, negative regulation of fibroblast proliferation, negative regulation of growth of symbiont in host, positive regulation of chronic inflammatory response to antigenic stimulus, positive regulation of humoral immune response mediated by circulating immunoglobulin, positive regulation of interferon-gamma production, response to drug, response to hypoxia, response to lipopolysaccharide, response to nutrient, signal transduction extracellular space, membrane cytokine activity, receptor binding, tumor necrosis factor receptor binding Human LTA4H HPA UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0019370=PMID:15078870, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0004463=Reactome:REACT_15478, GO:0006691=Reactome:REACT_150420, GO:0005829=Reactome:REACT_15478, GO:0005737=GO_REF:0000052, GO:0006954=PMID:11175901, GO:0004177=PMID:15078870, GO:0006508=GO_REF:0000037, GO:0008270=PMID:15078870, GO:0008233=PMID:1881903, GO:0043171=PMID:15078870, GO:0008237=GO_REF:0000037, GO:0004301=PMID:15078870} P09960 Leukotriene A-4 hydrolase protein 20100326 {GO:0019369=TAS, GO:0019370=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0004463=TAS, GO:0006691=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0006954=NAS, GO:0004177=IDA, GO:0006508=IEA, GO:0008270=IDA, GO:0008233=TAS, GO:0043171=IDA, GO:0008237=IEA, GO:0004301=IDA} arachidonic acid metabolic process, inflammatory response, leukotriene biosynthetic process, leukotriene metabolic process, peptide catabolic process, proteolysis, small molecule metabolic process cytoplasm, cytosol, nucleolus, nucleus aminopeptidase activity, epoxide hydrolase activity, leukotriene-A4 hydrolase activity, metallopeptidase activity, peptidase activity, zinc ion binding Human LTB PINC UniProtKB {GO:0005164=GO_REF:0000002, GO:0010467=GO_REF:0000019, GO:0005102=PMID:7916655, GO:0007267=PMID:7916655, GO:0005575=GO_REF:0000015, GO:0005125=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0048535=GO_REF:0000019, GO:0007165=PMID:7916655, GO:0006955=GO_REF:0000002, GO:0045084=GO_REF:0000024, GO:0043588=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q06643 Lymphotoxin-beta protein 20030904 {GO:0005164=IEA, GO:0010467=IEA, GO:0005102=TAS, GO:0007267=TAS, GO:0005575=ND, GO:0005125=IEA, GO:0005615=IEA, GO:0048535=IEA, GO:0007165=TAS, GO:0006955=IEA, GO:0045084=ISS, GO:0043588=IEA, GO:0016021=IEA} cell-cell signaling, gene expression, immune response, lymph node development, positive regulation of interleukin-12 biosynthetic process, signal transduction, skin development cellular_component, extracellular space, integral to membrane cytokine activity, receptor binding, tumor necrosis factor receptor binding Human LTB4R Reactome UniProtKB {GO:0006955=PMID:9177352, GO:0006936=PMID:8702478, GO:0006954=GO_REF:0000019, GO:0005886=Reactome:REACT_22436, GO:0000166=PMID:8702478, GO:0007186=PMID:9177352, GO:0005887=PMID:9177352, GO:0007200=PMID:8702478, GO:0006928=PMID:9177352, GO:0001632=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0004974=PMID:9177352} Q15722 Leukotriene B4 receptor 1 protein 20090326 {GO:0006955=TAS, GO:0006936=TAS, GO:0006954=IEA, GO:0005886=TAS, GO:0000166=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0007200=TAS, GO:0006928=TAS, GO:0001632=IEA, GO:0016021=IEA, GO:0004974=TAS} G-protein coupled receptor signaling pathway, cellular component movement, immune response, inflammatory response, muscle contraction, phospholipase C-activating G-protein coupled receptor signaling pathway integral to membrane, integral to plasma membrane, plasma membrane leukotriene B4 receptor activity, leukotriene receptor activity, nucleotide binding Human LTBP1 BHF-UCL UniProtKB {GO:0005515=PMID:18677313, GO:0035583=PMID:18677313, GO:0019838=GO_REF:0000037, GO:0030198=Reactome:REACT_118779, GO:0005509=GO_REF:0000002, GO:0005578=PMID:8537398, GO:0005024=PMID:8537398, GO:0005576=Reactome:REACT_150295} Q14766 Latent-transforming growth factor beta-binding protein 1 protein 20120708 {GO:0005515=IPI, GO:0035583=TAS, GO:0019838=IEA, GO:0030198=TAS, GO:0005509=IEA, GO:0005578=NAS, GO:0005024=NAS, GO:0005576=TAS} extracellular matrix organization, sequestering of TGFbeta in extracellular matrix extracellular region, proteinaceous extracellular matrix calcium ion binding, growth factor binding, protein binding, transforming growth factor beta-activated receptor activity Human UniProtKB:Q86TH1 LTBP2 PINC UniProtKB {GO:0009306=PMID:8697098, GO:0019838=GO_REF:0000037, GO:0005509=GO_REF:0000002, GO:0005578=PMID:7798248, GO:0007179=PMID:8697098, GO:0006605=PMID:7798248, GO:0008201=GO_REF:0000037} Q14767 Latent-transforming growth factor beta-binding protein 2 protein 20030904 {GO:0009306=TAS, GO:0019838=IEA, GO:0005509=IEA, GO:0005578=TAS, GO:0007179=TAS, GO:0006605=TAS, GO:0008201=IEA} protein secretion, protein targeting, transforming growth factor beta receptor signaling pathway proteinaceous extracellular matrix calcium ion binding, growth factor binding, heparin binding Human LTBP3 Reactome UniProtKB {GO:0060430=GO_REF:0000019, GO:0019838=GO_REF:0000037, GO:0046849=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0045780=GO_REF:0000019, GO:0060349=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0007179=GO_REF:0000019, GO:0005576=Reactome:REACT_150269, GO:0032331=GO_REF:0000019, GO:0030502=GO_REF:0000019} Q9NS15 Latent-transforming growth factor beta-binding protein 3 protein 20130301 {GO:0060430=IEA, GO:0019838=IEA, GO:0046849=IEA, GO:0030198=TAS, GO:0045780=IEA, GO:0060349=IEA, GO:0005509=IEA, GO:0007179=IEA, GO:0005576=TAS, GO:0032331=IEA, GO:0030502=IEA} bone morphogenesis, bone remodeling, extracellular matrix organization, lung saccule development, negative regulation of bone mineralization, negative regulation of chondrocyte differentiation, positive regulation of bone resorption, transforming growth factor beta receptor signaling pathway extracellular region calcium ion binding, growth factor binding Human LTBP4 IntAct UniProtKB {GO:0005515=PMID:21078624, GO:0050431=PMID:9660815, GO:0005509=PMID:9660815, GO:0005578=PMID:9660815, GO:0005576=Reactome:REACT_150295, GO:0007275=PMID:9660815, GO:0005539=PMID:9660815, GO:0001558=PMID:9660815, GO:0030162=PMID:9660815, GO:0005178=PMID:9660815, GO:0030198=Reactome:REACT_118779, GO:0006457=PMID:9660815, GO:0005024=PMID:9660815, GO:0045595=PMID:9660815, GO:0007179=GO_REF:0000019, GO:0030252=PMID:9660815, GO:0017015=PMID:9660815} Q8N2S1 Latent-transforming growth factor beta-binding protein 4 protein 20130415 {GO:0005515=IPI, GO:0050431=IDA, GO:0005509=NAS, GO:0005578=IDA, GO:0005576=TAS, GO:0007275=TAS, GO:0005539=NAS, GO:0001558=TAS, GO:0030162=IDA, GO:0005178=NAS, GO:0030198=TAS, GO:0006457=TAS, GO:0005024=NAS, GO:0045595=TAS, GO:0007179=IEA, GO:0030252=TAS, GO:0017015=TAS} extracellular matrix organization, growth hormone secretion, multicellular organismal development, protein folding, regulation of cell differentiation, regulation of cell growth, regulation of proteolysis, regulation of transforming growth factor beta receptor signaling pathway, transforming growth factor beta receptor signaling pathway extracellular region, proteinaceous extracellular matrix calcium ion binding, glycosaminoglycan binding, integrin binding, protein binding, transforming growth factor beta binding, transforming growth factor beta-activated receptor activity Human UniProtKB:O15265 LTBR IntAct UniProtKB {GO:0005515=PMID:20732415, GO:0007165=PMID:8171323, GO:2001238=PMID:20732415, GO:0019048=GO_REF:0000037, GO:0046330=PMID:20732415, GO:0006915=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0071260=PMID:19593445, GO:0043123=PMID:12761501, GO:0031625=PMID:11279055, GO:0042802=PMID:20732415} P36941 Tumor necrosis factor receptor superfamily member 3 protein 20130415 {GO:0005515=IPI, GO:0007165=TAS, GO:2001238=IMP, GO:0019048=IEA, GO:0046330=IMP, GO:0006915=IEA, GO:0016021=IEA, GO:0071260=IEP, GO:0043123=IEP, GO:0031625=IPI, GO:0042802=IPI} apoptotic process, cellular response to mechanical stimulus, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of JNK cascade, positive regulation of extrinsic apoptotic signaling pathway, signal transduction, virus-host interaction integral to membrane identical protein binding, protein binding, ubiquitin protein ligase binding Human UniProtKB:P36941 LTC4S Reactome UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0005515=PMID:19233132, GO:0019370=GO_REF:0000037, GO:0005783=PMID:19233132, GO:0019372=Reactome:REACT_150209, GO:0044281=Reactome:REACT_111217, GO:0005635=Reactome:REACT_150273, GO:0004364=GO_REF:0000033, GO:0004464=PMID:8706658, GO:0006691=Reactome:REACT_150420, GO:0008289=PMID:8706658, GO:0043231=PMID:1454853, GO:0005640=GO_REF:0000039, GO:0004602=GO_REF:0000033, GO:0006750=GO_REF:0000033, GO:0005789=GO_REF:0000039, GO:2001300=Reactome:REACT_150320, GO:0016021=GO_REF:0000037, GO:0008047=GO_REF:0000002} Q16873 Leukotriene C4 synthase protein 20120224 {GO:0019369=TAS, GO:0005515=IPI, GO:0019370=IEA, GO:0005783=IDA, GO:0019372=TAS, GO:0044281=TAS, GO:0005635=TAS, GO:0004364=IBA, GO:0004464=IDA, GO:0006691=TAS, GO:0008289=IDA, GO:0043231=TAS, GO:0005640=IEA, GO:0004602=IBA, GO:0006750=IBA, GO:0005789=IEA, GO:2001300=TAS, GO:0016021=IEA, GO:0008047=IEA} arachidonic acid metabolic process, glutathione biosynthetic process, leukotriene biosynthetic process, leukotriene metabolic process, lipoxin metabolic process, lipoxygenase pathway, small molecule metabolic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle, nuclear envelope, nuclear outer membrane enzyme activator activity, glutathione peroxidase activity, glutathione transferase activity, leukotriene-C4 synthase activity, lipid binding, protein binding Human LTF IntAct UniProtKB {GO:0005515=PMID:1544444, GO:0006355=GO_REF:0000037, GO:0051701=Reactome:REACT_121237, GO:0004252=PMID:9770539, GO:0033214=Reactome:REACT_121118, GO:0005576=Reactome:REACT_121409, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0052572=Reactome:REACT_121042, GO:0006351=GO_REF:0000037, GO:0008199=GO_REF:0000002, GO:0006879=GO_REF:0000002, GO:0005737=GO_REF:0000019, GO:0006959=PMID:9770539, GO:0006508=GO_REF:0000037, GO:0097013=Reactome:REACT_121328, GO:0006826=GO_REF:0000002, GO:0008233=GO_REF:0000019, GO:0030141=PMID:11907569, GO:0090382=Reactome:REACT_121256, GO:0008201=PMID:11907569, GO:0042742=GO_REF:0000037} P02788 Lactotransferrin protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0051701=TAS, GO:0004252=TAS, GO:0033214=TAS, GO:0005576=TAS, GO:0005634=IEA, GO:0003677=IEA, GO:0052572=TAS, GO:0006351=IEA, GO:0008199=IEA, GO:0006879=IEA, GO:0005737=IEA, GO:0006959=TAS, GO:0006508=IEA, GO:0097013=TAS, GO:0006826=IEA, GO:0008233=IEA, GO:0030141=IDA, GO:0090382=TAS, GO:0008201=IDA, GO:0042742=IEA} cellular iron ion homeostasis, defense response to bacterium, humoral immune response, interaction with host, iron assimilation by chelation and transport, iron ion transport, phagosome maturation, proteolysis, regulation of transcription, DNA-dependent, response to host immune response, transcription, DNA-dependent cytoplasm, extracellular region, nucleus, phagocytic vesicle lumen, secretory granule DNA binding, ferric iron binding, heparin binding, peptidase activity, protein binding, serine-type endopeptidase activity Human UniProtKB:P62157 LTK BHF-UCL UniProtKB {GO:0005886=PMID:7685902, GO:0071300=PMID:17910947, GO:0008283=PMID:10445845, GO:0006915=PMID:10445845, GO:0005524=GO_REF:0000037, GO:0014065=PMID:9223670, GO:0007165=PMID:7685902, GO:0004672=PMID:10445845, GO:0016020=PMID:10445845, GO:0005887=PMID:7685902, GO:0010976=PMID:17910947, GO:0006468=PMID:9223670, GO:0016021=GO_REF:0000038, GO:0004713=PMID:7685902, GO:0004714=GO_REF:0000003, GO:0007169=GO_REF:0000002} P29376 Leukocyte tyrosine kinase receptor protein 20110707 {GO:0005886=TAS, GO:0071300=IMP, GO:0008283=IDA, GO:0006915=IDA, GO:0005524=IEA, GO:0014065=IMP, GO:0007165=TAS, GO:0004672=IDA, GO:0016020=IDA, GO:0005887=TAS, GO:0010976=IMP, GO:0006468=IDA, GO:0016021=IEA, GO:0004713=TAS, GO:0004714=IEA, GO:0007169=IEA} apoptotic process, cell proliferation, cellular response to retinoic acid, phosphatidylinositol 3-kinase cascade, positive regulation of neuron projection development, protein phosphorylation, signal transduction, transmembrane receptor protein tyrosine kinase signaling pathway integral to membrane, integral to plasma membrane, membrane, plasma membrane ATP binding, protein kinase activity, protein tyrosine kinase activity, transmembrane receptor protein tyrosine kinase activity Human LTN1 IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0016567=GO_REF:0000041, GO:0016874=GO_REF:0000037, GO:0008270=GO_REF:0000002} O94822 E3 ubiquitin-protein ligase listerin protein 20130415 {GO:0005515=IPI, GO:0016567=IEA, GO:0016874=IEA, GO:0008270=IEA} protein ubiquitination ligase activity, protein binding, zinc ion binding Human UniProtKB:Q92985 LTV1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q96GA3 Protein LTV1 homolog protein 20101115 {GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA} cytoplasm, nucleolus, nucleus Human LUC7L ENSEMBL UniProtKB {GO:0005634=GO_REF:0000019, GO:0050733=GO_REF:0000019, GO:0045843=GO_REF:0000019} Q9NQ29 Putative RNA-binding protein Luc7-like 1 protein 20130413 {GO:0005634=IEA, GO:0050733=IEA, GO:0045843=IEA} negative regulation of striated muscle tissue development nucleus RS domain binding Human Ensembl:ENSMUSP00000110627 LUC7L2 UniProtKB UniProtKB {GO:0016607=GO_REF:0000039, GO:0019899=PMID:19574390} Q9Y383 Putative RNA-binding protein Luc7-like 2 protein 20090713 {GO:0016607=IEA, GO:0019899=IPI} nuclear speck enzyme binding Human UniProtKB:Q6NYC1 LUC7L3 HPA UniProtKB {GO:0008380=PMID:10631324, GO:0005515=PMID:18663000, GO:0006397=GO_REF:0000037, GO:0016607=GO_REF:0000039, GO:0005886=GO_REF:0000052, GO:0006950=PMID:10754390, GO:0005730=GO_REF:0000052, GO:0006915=PMID:10754390, GO:0005634=GO_REF:0000052, GO:0003729=PMID:10631324, GO:0003677=GO_REF:0000037, GO:0005925=GO_REF:0000052} O95232 Luc7-like protein 3 protein 20101115 {GO:0008380=IMP, GO:0005515=IPI, GO:0006397=IEA, GO:0016607=IEA, GO:0005886=IDA, GO:0006950=IMP, GO:0005730=IDA, GO:0006915=IMP, GO:0005634=IDA, GO:0003729=IMP, GO:0003677=IEA, GO:0005925=IDA} RNA splicing, apoptotic process, mRNA processing, response to stress focal adhesion, nuclear speck, nucleolus, nucleus, plasma membrane DNA binding, mRNA binding, protein binding Human LUM BHF-UCL UniProtKB {GO:0014070=GO_REF:0000019, GO:0051216=GO_REF:0000019, GO:0005796=Reactome:REACT_121317, GO:0005975=Reactome:REACT_474, GO:0005518=PMID:10892350, GO:0005578=PMID:7665616, GO:0005576=Reactome:REACT_121303, GO:0044281=Reactome:REACT_111217, GO:0070848=GO_REF:0000019, GO:0005583=PMID:10734230, GO:0042339=Reactome:REACT_121288, GO:0031012=PMID:22261194, GO:0018146=Reactome:REACT_121120, GO:0045944=GO_REF:0000019, GO:0030199=PMID:10892350, GO:0042340=Reactome:REACT_121313, GO:0030203=Reactome:REACT_121315, GO:0007601=GO_REF:0000002, GO:0043202=Reactome:REACT_121303, GO:0005201=PMID:10892350} P51884 Lumican protein 20120228 {GO:0014070=IEA, GO:0051216=IEA, GO:0005796=TAS, GO:0005975=TAS, GO:0005518=IDA, GO:0005578=TAS, GO:0005576=TAS, GO:0044281=TAS, GO:0070848=IEA, GO:0005583=IDA, GO:0042339=TAS, GO:0031012=ISS, GO:0018146=TAS, GO:0045944=IEA, GO:0030199=NAS, GO:0042340=TAS, GO:0030203=TAS, GO:0007601=IEA, GO:0043202=TAS, GO:0005201=NAS} carbohydrate metabolic process, cartilage development, collagen fibril organization, glycosaminoglycan metabolic process, keratan sulfate biosynthetic process, keratan sulfate catabolic process, keratan sulfate metabolic process, positive regulation of transcription from RNA polymerase II promoter, response to growth factor stimulus, response to organic cyclic compound, small molecule metabolic process, visual perception Golgi lumen, extracellular matrix, extracellular region, fibrillar collagen, lysosomal lumen, proteinaceous extracellular matrix collagen binding, extracellular matrix structural constituent colocalizes_with Human UniProtKB:F1SQ09 LUZP1 UniProtKB UniProtKB {GO:0021503=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0003281=GO_REF:0000019, GO:0060840=GO_REF:0000019} Q86V48 Leucine zipper protein 1 protein 20130413 {GO:0021503=IEA, GO:0005634=IEA, GO:0003281=IEA, GO:0060840=IEA} artery development, neural fold bending, ventricular septum development nucleus Human UniProtKB-SubCell:SL-0191 LXN UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0006954=GO_REF:0000037, GO:0008191=GO_REF:0000019, GO:0050965=GO_REF:0000019, GO:0008201=GO_REF:0000037} Q9BS40 Latexin protein 20130413 {GO:0005737=IEA, GO:0006954=IEA, GO:0008191=IEA, GO:0050965=IEA, GO:0008201=IEA} detection of temperature stimulus involved in sensory perception of pain, inflammatory response cytoplasm heparin binding, metalloendopeptidase inhibitor activity Human UniProtKB-SubCell:SL-0086 LY6D PINC UniProtKB {GO:0035634=GO_REF:0000019, GO:0016020=PMID:7790363, GO:0005886=GO_REF:0000039, GO:0009986=GO_REF:0000019, GO:0030098=GO_REF:0000019, GO:0031225=GO_REF:0000037, GO:0007155=GO_REF:0000037} Q14210 Lymphocyte antigen 6D protein 20030904 {GO:0035634=IEA, GO:0016020=TAS, GO:0005886=IEA, GO:0009986=IEA, GO:0030098=IEA, GO:0031225=IEA, GO:0007155=IEA} cell adhesion, lymphocyte differentiation, response to stilbenoid anchored to membrane, cell surface, membrane, plasma membrane Human LY6E PINC UniProtKB {GO:0042415=GO_REF:0000019, GO:0055010=GO_REF:0000019, GO:0030325=GO_REF:0000019, GO:0005887=PMID:8650192, GO:0035265=GO_REF:0000019, GO:0031225=GO_REF:0000037, GO:0001701=GO_REF:0000019, GO:0007166=PMID:8650192, GO:0048242=GO_REF:0000019} Q16553 Lymphocyte antigen 6E protein 20030904 {GO:0042415=IEA, GO:0055010=IEA, GO:0030325=IEA, GO:0005887=TAS, GO:0035265=IEA, GO:0031225=IEA, GO:0001701=IEA, GO:0007166=TAS, GO:0048242=IEA} adrenal gland development, cell surface receptor signaling pathway, epinephrine secretion, in utero embryonic development, norepinephrine metabolic process, organ growth, ventricular cardiac muscle tissue morphogenesis anchored to membrane, integral to plasma membrane Human LY6G5B UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005576=GO_REF:0000039, GO:0005575=GO_REF:0000015} Q8NDX9 Lymphocyte antigen 6 complex locus protein G5b protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0005576=IEA, GO:0005575=ND} biological_process cellular_component, extracellular region molecular_function Human LY6G6F UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q5SQ64 Lymphocyte antigen 6 complex locus protein G6f protein 20130413 {GO:0005886=IEA, GO:0016021=IEA} integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 LY6H PINC UniProtKB {GO:0005886=GO_REF:0000039, GO:0009887=PMID:9799603, GO:0031225=GO_REF:0000037, GO:0007399=PMID:9799603} O94772 Lymphocyte antigen 6H protein 20030904 {GO:0005886=IEA, GO:0009887=TAS, GO:0031225=IEA, GO:0007399=TAS} nervous system development, organ morphogenesis anchored to membrane, plasma membrane Human LY6K HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005576=GO_REF:0000039, GO:0031225=GO_REF:0000037} Q17RY6 Lymphocyte antigen 6K protein 20101115 {GO:0005737=IDA, GO:0005886=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0005576=IEA, GO:0031225=IEA} anchored to membrane, cytoplasm, extracellular region, nucleolus, nucleus, plasma membrane Human LY86 MGI UniProtKB {GO:0006954=GO_REF:0000037, GO:0005886=PMID:9763566, GO:0008283=PMID:9763566, GO:0006959=PMID:9763566, GO:0045087=GO_REF:0000037, GO:0031666=PMID:10880523, GO:0006915=PMID:9763566, GO:0005615=GO_REF:0000039} O95711 Lymphocyte antigen 86 protein 20130305 {GO:0006954=IEA, GO:0005886=TAS, GO:0008283=TAS, GO:0006959=TAS, GO:0045087=IEA, GO:0031666=IGI, GO:0006915=TAS, GO:0005615=IEA} apoptotic process, cell proliferation, humoral immune response, inflammatory response, innate immune response, positive regulation of lipopolysaccharide-mediated signaling pathway extracellular space, plasma membrane Human UniProtKB:Q99467 LY9 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0016064=GO_REF:0000029, GO:0004872=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037} Q9HBG7 T-lymphocyte surface antigen Ly-9 protein 20021105 {GO:0003674=ND, GO:0016064=NAS, GO:0004872=IEA, GO:0016021=IEA, GO:0007155=IEA} cell adhesion, immunoglobulin mediated immune response integral to membrane molecular_function, receptor activity Human LY96 GOC UniProtKB {GO:0046696=PMID:19252480, GO:0005515=PMID:17803912, GO:0038124=Reactome:REACT_8006, GO:0034142=Reactome:REACT_6894, GO:0038123=Reactome:REACT_8005, GO:0005886=Reactome:REACT_150418, GO:0034134=Reactome:REACT_7980, GO:0007249=Reactome:REACT_25351, GO:0001875=PMID:19252480, GO:0015026=PMID:10359581, GO:0002224=Reactome:REACT_6966, GO:0005615=GO_REF:0000039, GO:0002756=Reactome:REACT_6809, GO:0006968=PMID:10359581, GO:0006954=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0002755=Reactome:REACT_6788, GO:0032496=PMID:12594207, GO:0032497=PMID:19252480, GO:0035666=Reactome:REACT_25281, GO:0031663=PMID:19252480, GO:0034138=Reactome:REACT_6783, GO:0010008=Reactome:REACT_150447, GO:0007166=PMID:10359581} Q9Y6Y9 Lymphocyte antigen 96 protein 20130413 {GO:0046696=IDA, GO:0005515=IPI, GO:0038124=TAS, GO:0034142=TAS, GO:0038123=TAS, GO:0005886=TAS, GO:0034134=TAS, GO:0007249=TAS, GO:0001875=IDA, GO:0015026=TAS, GO:0002224=TAS, GO:0005615=IEA, GO:0002756=TAS, GO:0006968=TAS, GO:0006954=IEA, GO:0045087=TAS, GO:0002755=TAS, GO:0032496=IDA, GO:0032497=IDA, GO:0035666=TAS, GO:0031663=IDA, GO:0034138=TAS, GO:0010008=TAS, GO:0007166=TAS} I-kappaB kinase/NF-kappaB cascade, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, cell surface receptor signaling pathway, cellular defense response, detection of lipopolysaccharide, inflammatory response, innate immune response, lipopolysaccharide-mediated signaling pathway, response to lipopolysaccharide, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway endosome membrane, extracellular space, lipopolysaccharide receptor complex, plasma membrane coreceptor activity, lipopolysaccharide receptor activity, protein binding Human LYAR LIFEdb UniProtKB {GO:0005730=GO_REF:0000054, GO:0046872=GO_REF:0000037} Q9NX58 Cell growth-regulating nucleolar protein protein 20100607 {GO:0005730=IDA, GO:0046872=IEA} nucleolus metal ion binding Human LYL1 UniProtKB UniProtKB {GO:0005515=PMID:18160048, GO:0006355=PMID:10023675, GO:0030183=GO_REF:0000024, GO:0046983=GO_REF:0000002, GO:0060216=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0045893=PMID:18160048, GO:0003677=PMID:18160048, GO:0001955=PMID:20418284, GO:0006351=GO_REF:0000037} P12980 Protein lyl-1 protein 20101112 {GO:0005515=IPI, GO:0006355=IDA, GO:0030183=ISS, GO:0046983=IEA, GO:0060216=ISS, GO:0005634=IEA, GO:0045893=IDA, GO:0003677=IDA, GO:0001955=IMP, GO:0006351=IEA} B cell differentiation, blood vessel maturation, definitive hemopoiesis, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, protein binding, protein dimerization activity Human UniProtKB:P27792 LYN GOC UniProtKB {GO:0051219=GO_REF:0000019, GO:0005515=PMID:23001182, GO:0070447=GO_REF:0000019, GO:0071300=PMID:17910947, GO:0002513=GO_REF:0000024, GO:0001817=GO_REF:0000024, GO:0046777=PMID:7682714, GO:0031625=GO_REF:0000019, GO:0030061=GO_REF:0000019, GO:0010741=GO_REF:0000024, GO:0043304=GO_REF:0000024, GO:0032868=GO_REF:0000019, GO:0005794=GO_REF:0000052, GO:0030889=GO_REF:0000019, GO:0009636=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0018108=PMID:7682714, GO:0044325=PMID:12538589, GO:0005178=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0045646=GO_REF:0000024, GO:0050853=GO_REF:0000019, GO:0033628=PMID:18802065, GO:0050855=GO_REF:0000024, GO:0048471=PMID:20605918, GO:0050663=GO_REF:0000019, GO:0001782=GO_REF:0000024, GO:0005634=PMID:18817770, GO:0060397=Reactome:REACT_111133, GO:0097028=GO_REF:0000024, GO:0005829=Reactome:REACT_160304, GO:0043208=GO_REF:0000019, GO:0034666=GO_REF:0000019, GO:0002774=GO_REF:0000024, GO:0009725=GO_REF:0000024, GO:0043200=GO_REF:0000019, GO:0090330=GO_REF:0000024, GO:0050727=GO_REF:0000019, GO:0042981=PMID:11517336, GO:0060252=GO_REF:0000019, GO:0006974=PMID:11517336, GO:0007596=Reactome:REACT_604, GO:0014003=GO_REF:0000019, GO:0002576=GO_REF:0000024, GO:0030218=GO_REF:0000024, GO:0070668=PMID:11435302, GO:0070667=GO_REF:0000024, GO:0014070=GO_REF:0000019, GO:0070304=PMID:10891478, GO:0002762=GO_REF:0000019, GO:0050900=Reactome:REACT_12051, GO:0048678=GO_REF:0000019, GO:0031175=GO_REF:0000019, GO:0043231=GO_REF:0000052, GO:0034605=GO_REF:0000019, GO:0005758=GO_REF:0000019, GO:0009743=GO_REF:0000019, GO:0043552=GO_REF:0000019, GO:0031668=GO_REF:0000019, GO:0002902=GO_REF:0000019, GO:0070373=GO_REF:0000024, GO:0031663=GO_REF:0000024, GO:0070372=GO_REF:0000024, GO:0023014=PMID:10748115, GO:0042531=GO_REF:0000024, GO:0030335=GO_REF:0000019, GO:0006991=GO_REF:0000019, GO:0014069=GO_REF:0000019, GO:0005161=GO_REF:0000019, GO:0002768=GO_REF:0000024, GO:0050777=PMID:15489917, GO:0010976=PMID:17910947, GO:0050707=GO_REF:0000019, GO:0045121=PMID:11313396, GO:2000670=GO_REF:0000024, GO:0090025=PMID:18802065, GO:0002431=GO_REF:0000024, GO:0038096=Reactome:REACT_160123, GO:0034144=GO_REF:0000024, GO:0017124=GO_REF:0000019, GO:0008284=GO_REF:0000024, GO:0008285=PMID:14726379, GO:0005886=GO_REF:0000052, GO:0051279=GO_REF:0000019, GO:0031295=Reactome:REACT_19344, GO:0033003=GO_REF:0000024, GO:0035556=GO_REF:0000019, GO:0005737=GO_REF:0000024, GO:0043407=GO_REF:0000024, GO:0034136=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0007165=PMID:7650013, GO:0002553=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0001933=GO_REF:0000024, GO:0001932=PMID:15489917, GO:0006468=PMID:3561390, GO:0004713=Reactome:REACT_111112, GO:0004715=Reactome:REACT_111235, GO:0007169=PMID:14726379, GO:0051272=PMID:16467205, GO:0060369=GO_REF:0000019, GO:0004716=PMID:10748115} P07948 Tyrosine-protein kinase Lyn protein 20130413 {GO:0051219=IEA, GO:0005515=IPI, GO:0070447=IEA, GO:0071300=IMP, GO:0002513=ISS, GO:0001817=ISS, GO:0046777=IDA, GO:0031625=IEA, GO:0030061=IEA, GO:0010741=ISS, GO:0043304=ISS, GO:0032868=IEA, GO:0005794=IDA, GO:0030889=IEA, GO:0009636=IEA, GO:0030168=TAS, GO:0018108=IDA, GO:0044325=IPI, GO:0005178=IEA, GO:0045087=TAS, GO:0045646=ISS, GO:0050853=IEA, GO:0033628=IMP, GO:0050855=ISS, GO:0048471=IDA, GO:0050663=IEA, GO:0001782=ISS, GO:0005634=IDA, GO:0060397=TAS, GO:0097028=ISS, GO:0005829=TAS, GO:0043208=IEA, GO:0034666=IEA, GO:0002774=ISS, GO:0009725=ISS, GO:0043200=IEA, GO:0090330=ISS, GO:0050727=IEA, GO:0042981=IDA, GO:0060252=IEA, GO:0006974=IDA, GO:0007596=TAS, GO:0014003=IEA, GO:0002576=ISS, GO:0030218=ISS, GO:0070668=IMP, GO:0070667=ISS, GO:0014070=IEA, GO:0070304=IDA, GO:0002762=IEA, GO:0050900=TAS, GO:0048678=IEA, GO:0031175=IEA, GO:0043231=IDA, GO:0034605=IEA, GO:0005758=IEA, GO:0009743=IEA, GO:0043552=IEA, GO:0031668=IEA, GO:0002902=IEA, GO:0070373=ISS, GO:0031663=ISS, GO:0070372=ISS, GO:0023014=TAS, GO:0042531=ISS, GO:0030335=IEA, GO:0006991=IEA, GO:0014069=IEA, GO:0005161=IEA, GO:0002768=ISS, GO:0050777=TAS, GO:0010976=IMP, GO:0050707=IEA, GO:0045121=IDA, GO:2000670=ISS, GO:0090025=IMP, GO:0002431=ISS, GO:0038096=TAS, GO:0034144=ISS, GO:0017124=IEA, GO:0008284=ISS, GO:0008285=IMP, GO:0005886=IDA, GO:0051279=IEA, GO:0031295=TAS, GO:0033003=ISS, GO:0035556=IEA, GO:0005737=ISS, GO:0043407=ISS, GO:0034136=ISS, GO:0005524=IEA, GO:0007165=TAS, GO:0002553=IEA, GO:0019048=IEA, GO:0001933=ISS, GO:0001932=TAS, GO:0006468=TAS, GO:0004713=TAS, GO:0004715=TAS, GO:0007169=IMP, GO:0051272=IDA, GO:0060369=IEA, GO:0004716=TAS} B cell homeostasis, B cell receptor signaling pathway, Fc receptor mediated inhibitory signaling pathway, Fc receptor mediated stimulatory signaling pathway, Fc-gamma receptor signaling pathway involved in phagocytosis, JAK-STAT cascade involved in growth hormone signaling pathway, T cell costimulation, blood coagulation, cellular response to extracellular stimulus, cellular response to heat, cellular response to retinoic acid, cytokine secretion, dendritic cell differentiation, erythrocyte differentiation, histamine secretion by mast cell, immune response-regulating cell surface receptor signaling pathway, innate immune response, intracellular signal transduction, leukocyte migration, lipopolysaccharide-mediated signaling pathway, negative regulation of B cell proliferation, negative regulation of ERK1 and ERK2 cascade, negative regulation of MAP kinase activity, negative regulation of cell proliferation, negative regulation of immune response, negative regulation of intracellular protein kinase cascade, negative regulation of mast cell proliferation, negative regulation of myeloid leukocyte differentiation, negative regulation of protein phosphorylation, negative regulation of toll-like receptor 2 signaling pathway, negative regulation of toll-like receptor 4 signaling pathway, neuron projection development, oligodendrocyte development, peptidyl-tyrosine phosphorylation, platelet activation, platelet degranulation, positive regulation of Fc receptor mediated stimulatory signaling pathway, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of cellular component movement, positive regulation of dendritic cell apoptotic process, positive regulation of glial cell proliferation, positive regulation of mast cell proliferation, positive regulation of neuron projection development, positive regulation of oligodendrocyte progenitor proliferation, positive regulation of phosphatidylinositol 3-kinase activity, positive regulation of stress-activated protein kinase signaling cascade, positive regulation of tyrosine phosphorylation of STAT protein, protein autophosphorylation, protein phosphorylation, regulation of B cell apoptotic process, regulation of B cell receptor signaling pathway, regulation of ERK1 and ERK2 cascade, regulation of apoptotic process, regulation of cell adhesion mediated by integrin, regulation of cytokine production, regulation of cytokine secretion, regulation of erythrocyte differentiation, regulation of inflammatory response, regulation of mast cell activation, regulation of mast cell degranulation, regulation of monocyte chemotaxis, regulation of platelet aggregation, regulation of protein phosphorylation, regulation of release of sequestered calcium ion into cytosol, response to DNA damage stimulus, response to amino acid stimulus, response to axon injury, response to carbohydrate stimulus, response to hormone stimulus, response to insulin stimulus, response to organic cyclic compound, response to sterol depletion, response to toxic substance, signal transduction, signal transduction by phosphorylation, tolerance induction to self antigen, transmembrane receptor protein tyrosine kinase signaling pathway, virus-host interaction Golgi apparatus, alpha2-beta1 integrin complex, cytoplasm, cytosol, intracellular membrane-bounded organelle, membrane raft, mitochondrial crista, mitochondrial intermembrane space, nucleus, perinuclear region of cytoplasm, plasma membrane, postsynaptic density ATP binding, SH3 domain binding, glycosphingolipid binding, integrin binding, ion channel binding, non-membrane spanning protein tyrosine kinase activity, phosphoprotein binding, platelet-derived growth factor receptor binding, protein binding, protein tyrosine kinase activity, receptor signaling protein tyrosine kinase activity, ubiquitin protein ligase binding Human LYPD3 HGNC UniProtKB {GO:0007160=GO_REF:0000019, GO:0043236=GO_REF:0000019, GO:0006928=GO_REF:0000019, GO:0016021=GO_REF:0000019, GO:0046658=PMID:15012588} O95274 Ly6/PLAUR domain-containing protein 3 protein 20060209 {GO:0007160=IEA, GO:0043236=IEA, GO:0006928=IEA, GO:0016021=IEA, GO:0046658=TAS} cell-matrix adhesion, cellular component movement anchored to plasma membrane, integral to membrane laminin binding Human LYPD6B UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0031225=GO_REF:0000037} Q8NI32 Ly6/PLAUR domain-containing protein 6B protein 20130413 {GO:0005886=IEA, GO:0031225=IEA} anchored to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 LYPLA1 Reactome UniProtKB {GO:0005739=GO_REF:0000019, GO:0016787=GO_REF:0000002, GO:0008474=Reactome:REACT_12463, GO:0004622=PMID:10064899, GO:0050999=Reactome:REACT_12477, GO:0006631=GO_REF:0000037, GO:0046209=Reactome:REACT_12508, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_12463} O75608 Acyl-protein thioesterase 1 protein 20130213 {GO:0005739=IEA, GO:0016787=IEA, GO:0008474=TAS, GO:0004622=TAS, GO:0050999=TAS, GO:0006631=IEA, GO:0046209=TAS, GO:0044281=TAS, GO:0005829=TAS} fatty acid metabolic process, nitric oxide metabolic process, regulation of nitric-oxide synthase activity, small molecule metabolic process cytosol, mitochondrion hydrolase activity, lysophospholipase activity, palmitoyl-(protein) hydrolase activity Human LYPLA2 InterPro UniProtKB {GO:0005737=GO_REF:0000039, GO:0016787=GO_REF:0000002, GO:0006631=GO_REF:0000037} Q5QPQ3 Acyl-protein thioesterase 2 protein 20130413 {GO:0005737=IEA, GO:0016787=IEA, GO:0006631=IEA} fatty acid metabolic process cytoplasm hydrolase activity Human InterPro:IPR003140 LYPLAL1 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000039, GO:0004622=PMID:12706107, GO:0005575=GO_REF:0000015} Q5VWZ2 Lysophospholipase-like protein 1 protein 20080924 {GO:0008150=ND, GO:0005737=IEA, GO:0004622=NAS, GO:0005575=ND} biological_process cellular_component, cytoplasm lysophospholipase activity Human LYRM1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0005634=GO_REF:0000039} O43325 LYR motif-containing protein 1 protein 20130413 {GO:0005739=IEA, GO:0005634=IEA} mitochondrion, nucleus Human UniProtKB-SubCell:SL-0191 LYRM2 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019} Q9NU23 LYR motif-containing protein 2 protein 20130413 {GO:0005739=IEA} mitochondrion Human Ensembl:ENSMUSP00000061451 LYRM4 HPA UniProtKB {GO:0005739=GO_REF:0000019, GO:0005759=Reactome:REACT_150385, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217} Q9HD34 LYR motif-containing protein 4 protein 20111111 {GO:0005739=IEA, GO:0005759=TAS, GO:0005634=IDA, GO:0044281=TAS} small molecule metabolic process mitochondrial matrix, mitochondrion, nucleus Human LYRM7 UniProtKB UniProtKB {GO:0005759=GO_REF:0000039} Q5U5X0 Complex III assembly factor LYRM7 protein 20130413 {GO:0005759=IEA} mitochondrial matrix Human UniProtKB-SubCell:SL-0170 LYST UniProtKB UniProtKB {GO:0005515=PMID:11984006, GO:0002446=GO_REF:0000019, GO:0030595=GO_REF:0000024, GO:0032438=GO_REF:0000024, GO:0042267=PMID:10648412, GO:0042493=GO_REF:0000019, GO:0042832=GO_REF:0000024, GO:0005829=GO_REF:0000019, GO:0032816=GO_REF:0000019, GO:0051607=GO_REF:0000024, GO:0032510=PMID:9606205, GO:0007596=GO_REF:0000019, GO:0033299=GO_REF:0000019, GO:0015630=PMID:9606205, GO:0043473=PMID:10648412, GO:0055091=GO_REF:0000019, GO:0033364=GO_REF:0000024, GO:0006644=GO_REF:0000019, GO:0007017=GO_REF:0000019, GO:0007040=GO_REF:0000019, GO:0042742=GO_REF:0000024, GO:0002456=GO_REF:0000019} Q99698 Lysosomal-trafficking regulator protein 20080612 {GO:0005515=IPI, GO:0002446=IEA, GO:0030595=ISS, GO:0032438=ISS, GO:0042267=IMP, GO:0042493=IEA, GO:0042832=ISS, GO:0005829=IEA, GO:0032816=IEA, GO:0051607=ISS, GO:0032510=IMP, GO:0007596=IEA, GO:0033299=IEA, GO:0015630=IDA, GO:0043473=IMP, GO:0055091=IEA, GO:0033364=ISS, GO:0006644=IEA, GO:0007017=IEA, GO:0007040=IEA, GO:0042742=ISS, GO:0002456=IEA} T cell mediated immunity, blood coagulation, defense response to bacterium, defense response to protozoan, defense response to virus, endosome to lysosome transport via multivesicular body sorting pathway, leukocyte chemotaxis, lysosome organization, mast cell secretory granule organization, melanosome organization, microtubule-based process, natural killer cell mediated cytotoxicity, neutrophil mediated immunity, phospholipid homeostasis, phospholipid metabolic process, pigmentation, positive regulation of natural killer cell activation, response to drug, secretion of lysosomal enzymes cytosol, microtubule cytoskeleton protein binding Human UniProtKB:Q9NRX2 LYZ Reactome UniProtKB {GO:0006954=PMID:366724, GO:0016998=GO_REF:0000002, GO:0019835=GO_REF:0000037, GO:0003796=PMID:2829884, GO:0005576=Reactome:REACT_75905, GO:0005615=PMID:2829884, GO:0042742=GO_REF:0000037} P61626 Lysozyme C protein 20101014 {GO:0006954=TAS, GO:0016998=IEA, GO:0019835=IEA, GO:0003796=TAS, GO:0005576=TAS, GO:0005615=TAS, GO:0042742=IEA} cell wall macromolecule catabolic process, cytolysis, defense response to bacterium, inflammatory response extracellular region, extracellular space lysozyme activity Human LZIC RefGenome UniProtKB {GO:0008013=GO_REF:0000002, GO:0010212=GO_REF:0000019, GO:0007417=GO_REF:0000033} Q8WZA0 Protein LZIC protein 20120414 {GO:0008013=IEA, GO:0010212=IEA, GO:0007417=IBA} central nervous system development, response to ionizing radiation beta-catenin binding Human PANTHER:PTN000421031 LZTFL1 IntAct UniProtKB {GO:0042802=PMID:22072986} Q9NQ48 Leucine zipper transcription factor-like protein 1 protein 20130415 {GO:0042802=IPI} identical protein binding Human UniProtKB:Q9NQ48 LZTR1 GOC UniProtKB {GO:0006355=PMID:7633402, GO:0003700=PMID:7633402, GO:0009653=PMID:7633402} Q8N653 Leucine-zipper-like transcriptional regulator 1 protein 20130413 {GO:0006355=TAS, GO:0003700=TAS, GO:0009653=TAS} anatomical structure morphogenesis, regulation of transcription, DNA-dependent sequence-specific DNA binding transcription factor activity Human LZTS1 HPA UniProtKB {GO:0005515=PMID:22354037, GO:0010467=Reactome:REACT_71, GO:0006386=Reactome:REACT_63, GO:0006355=GO_REF:0000029, GO:0005794=GO_REF:0000052, GO:0006385=Reactome:REACT_756, GO:0030054=GO_REF:0000037, GO:0003700=PMID:10097140, GO:0005886=GO_REF:0000052, GO:0016242=PMID:22354037, GO:0005730=GO_REF:0000052, GO:0014069=GO_REF:0000039, GO:0005634=GO_REF:0000029, GO:0006383=Reactome:REACT_1371, GO:0003677=PMID:10097140, GO:0044297=GO_REF:0000019, GO:0006351=PMID:10097140, GO:0048814=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0007049=GO_REF:0000037, GO:0016324=GO_REF:0000019, GO:0043198=GO_REF:0000019, GO:0045211=GO_REF:0000019, GO:0005654=Reactome:REACT_1779} Q9Y250 Leucine zipper putative tumor suppressor 1 protein 20100326 {GO:0005515=IPI, GO:0010467=TAS, GO:0006386=TAS, GO:0006355=NAS, GO:0005794=IDA, GO:0006385=TAS, GO:0030054=IEA, GO:0003700=TAS, GO:0005886=IDA, GO:0016242=IMP, GO:0005730=IDA, GO:0014069=IEA, GO:0005634=NAS, GO:0006383=TAS, GO:0003677=NAS, GO:0044297=IEA, GO:0006351=NAS, GO:0048814=IEA, GO:0005737=IDA, GO:0007049=IEA, GO:0016324=IEA, GO:0043198=IEA, GO:0045211=IEA, GO:0005654=TAS} cell cycle, gene expression, negative regulation of macroautophagy, regulation of dendrite morphogenesis, regulation of transcription, DNA-dependent, termination of RNA polymerase III transcription, transcription elongation from RNA polymerase III promoter, transcription from RNA polymerase III promoter, transcription, DNA-dependent Golgi apparatus, apical plasma membrane, cell body, cell junction, cytoplasm, dendritic shaft, nucleolus, nucleoplasm, nucleus, plasma membrane, postsynaptic density, postsynaptic membrane DNA binding, protein binding, sequence-specific DNA binding transcription factor activity Human LZTS2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0007067=GO_REF:0000037, GO:0005815=GO_REF:0000039, GO:0005874=GO_REF:0000037, GO:0016055=GO_REF:0000037, GO:0051301=GO_REF:0000037} Q9BRK4 Leucine zipper putative tumor suppressor 2 protein 20130413 {GO:0005737=IEA, GO:0007067=IEA, GO:0005815=IEA, GO:0005874=IEA, GO:0016055=IEA, GO:0051301=IEA} Wnt receptor signaling pathway, cell division, mitosis cytoplasm, microtubule, microtubule organizing center Human UniProtKB-SubCell:SL-0048 M6PR MGI UniProtKB {GO:0015578=GO_REF:0000002, GO:0000323=GO_REF:0000002, GO:0009986=PMID:12493773, GO:0005887=PMID:10799489, GO:0005770=GO_REF:0000019, GO:0008333=PMID:10799489, GO:0016021=GO_REF:0000002, GO:0005765=GO_REF:0000039, GO:0005537=GO_REF:0000002, GO:0006898=PMID:10799489, GO:0005768=PMID:15078902, GO:0004888=PMID:10799489} P20645 Cation-dependent mannose-6-phosphate receptor protein 20050930 {GO:0015578=IEA, GO:0000323=IEA, GO:0009986=IDA, GO:0005887=TAS, GO:0005770=IEA, GO:0008333=TAS, GO:0016021=IEA, GO:0005765=IEA, GO:0005537=IEA, GO:0006898=TAS, GO:0005768=IDA, GO:0004888=TAS} endosome to lysosome transport, receptor-mediated endocytosis cell surface, endosome, integral to membrane, integral to plasma membrane, late endosome, lysosomal membrane, lytic vacuole mannose binding, mannose transmembrane transporter activity, transmembrane signaling receptor activity Human MAB21L1 PINC UniProtKB {GO:0008284=GO_REF:0000019, GO:0048568=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0043010=GO_REF:0000019, GO:0009653=PMID:8733127} Q13394 Protein mab-21-like 1 protein 20031119 {GO:0008284=IEA, GO:0048568=IEA, GO:0005634=IEA, GO:0043010=IEA, GO:0009653=TAS} anatomical structure morphogenesis, camera-type eye development, embryonic organ development, positive regulation of cell proliferation nucleus Human MAB21L2 PINC UniProtKB {GO:0010172=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0048568=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0043010=GO_REF:0000019, GO:0007399=PMID:10556287} Q9Y586 Protein mab-21-like 2 protein 20030904 {GO:0010172=IEA, GO:0008284=IEA, GO:0048568=IEA, GO:0005634=IEA, GO:0043010=IEA, GO:0007399=TAS} camera-type eye development, embryonic body morphogenesis, embryonic organ development, nervous system development, positive regulation of cell proliferation nucleus Human MACC1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0051781=GO_REF:0000037, GO:0008083=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6ZN28 Metastasis-associated in colon cancer protein 1 protein 20130413 {GO:0005737=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0051781=IEA, GO:0008083=IEA, GO:0006351=IEA} positive regulation of cell division, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus growth factor activity Human UniProtKB-SubCell:SL-0086 MACF1 GOC UniProtKB {GO:0008017=GO_REF:0000029, GO:0005515=PMID:17043677, GO:0006200=GO_REF:0000024, GO:0005886=PMID:20937854, GO:0043001=PMID:15265687, GO:0006928=GO_REF:0000019, GO:0030177=GO_REF:0000024, GO:0015629=GO_REF:0000019, GO:0051893=GO_REF:0000024, GO:0005737=PMID:16076900, GO:0051015=PMID:10529403, GO:0007050=GO_REF:0000002, GO:0016055=GO_REF:0000019, GO:0005856=PMID:10529403, GO:0016887=GO_REF:0000024, GO:0001707=GO_REF:0000019, GO:0005794=PMID:16076900, GO:0005509=GO_REF:0000029, GO:0005874=PMID:16076900, GO:0032886=PMID:20937854, GO:0003779=PMID:10559237, GO:0032587=PMID:20937854, GO:0008150=GO_REF:0000015, GO:0007163=GO_REF:0000019, GO:0042060=GO_REF:0000024, GO:0006620=GO_REF:0000019, GO:0010632=GO_REF:0000024} Q9UPN3 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 protein 20130413 {GO:0008017=NAS, GO:0005515=IPI, GO:0006200=ISS, GO:0005886=IDA, GO:0043001=IDA, GO:0006928=IEA, GO:0030177=ISS, GO:0015629=IEA, GO:0051893=ISS, GO:0005737=IDA, GO:0051015=NAS, GO:0007050=IEA, GO:0016055=IEA, GO:0005856=NAS, GO:0016887=ISS, GO:0001707=IEA, GO:0005794=IDA, GO:0005509=NAS, GO:0005874=IDA, GO:0032886=IMP, GO:0003779=IDA, GO:0032587=IDA, GO:0008150=ND, GO:0007163=IEA, GO:0042060=ISS, GO:0006620=IEA, GO:0010632=ISS} ATP catabolic process, Golgi to plasma membrane protein transport, Wnt receptor signaling pathway, biological_process, cell cycle arrest, cellular component movement, establishment or maintenance of cell polarity, mesoderm formation, positive regulation of Wnt receptor signaling pathway, posttranslational protein targeting to membrane, regulation of epithelial cell migration, regulation of focal adhesion assembly, regulation of microtubule-based process, wound healing Golgi apparatus, actin cytoskeleton, cytoplasm, cytoskeleton, microtubule, plasma membrane, ruffle membrane ATPase activity, actin binding, actin filament binding, calcium ion binding, microtubule binding, protein binding Human UniProtKB:Q9QXZ0 MACROD1 IntAct UniProtKB {GO:0005515=PMID:17914104, GO:0042278=PMID:21257746, GO:0005739=GO_REF:0000019, GO:0019213=PMID:21257746} Q9BQ69 O-acetyl-ADP-ribose deacetylase MACROD1 protein 20130415 {GO:0005515=IPI, GO:0042278=IDA, GO:0005739=IEA, GO:0019213=IDA} purine nucleoside metabolic process mitochondrion deacetylase activity, protein binding Human UniProtKB:P03372 MACROD2 UniProtKB UniProtKB {GO:0042278=PMID:21257746, GO:0007420=GO_REF:0000019, GO:0019213=PMID:21257746, GO:0005575=GO_REF:0000015} A1Z1Q3 O-acetyl-ADP-ribose deacetylase MACROD2 protein 20110909 {GO:0042278=IDA, GO:0007420=IEA, GO:0019213=IDA, GO:0005575=ND} brain development, purine nucleoside metabolic process cellular_component deacetylase activity Human MAD1L1 HPA UniProtKB {GO:0005515=PMID:21988832, GO:0000236=Reactome:REACT_682, GO:0072686=PMID:20133940, GO:0007094=Reactome:REACT_2137, GO:0007093=PMID:9546394, GO:0005813=PMID:9546394, GO:0005819=PMID:9546394, GO:0005634=GO_REF:0000052, GO:0090235=PMID:20133940, GO:0015629=GO_REF:0000052, GO:0005829=Reactome:REACT_150414, GO:0000093=PMID:9546394, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0005643=PMID:18981471, GO:0000089=PMID:9546394, GO:0000087=Reactome:REACT_910, GO:0000777=GO_REF:0000039, GO:0000075=Reactome:REACT_1538, GO:0000776=PMID:20133940, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q9Y6D9 Mitotic spindle assembly checkpoint protein MAD1 protein 20101115 {GO:0005515=IPI, GO:0000236=TAS, GO:0072686=IDA, GO:0007094=TAS, GO:0007093=NAS, GO:0005813=NAS, GO:0005819=NAS, GO:0005634=IDA, GO:0090235=IDA, GO:0015629=IDA, GO:0005829=TAS, GO:0000093=NAS, GO:0005739=IDA, GO:0005737=IDA, GO:0005643=IDA, GO:0000089=NAS, GO:0000087=TAS, GO:0000777=IEA, GO:0000075=TAS, GO:0000776=IDA, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, cell cycle checkpoint, cell division, mitotic anaphase, mitotic cell cycle, mitotic cell cycle checkpoint, mitotic metaphase, mitotic prometaphase, mitotic spindle assembly checkpoint, mitotic telophase, regulation of metaphase plate congression actin cytoskeleton, centrosome, condensed chromosome kinetochore, cytoplasm, cytosol, kinetochore, mitochondrion, mitotic spindle, nuclear pore, nucleus, spindle protein binding Human MAD2L1 BHF-UCL UniProtKB {GO:0005515=PMID:10527948, GO:0072686=PMID:20133940, GO:0000236=Reactome:REACT_682, GO:0007094=Reactome:REACT_2137, GO:0048471=PMID:20870947, GO:0007093=PMID:8824189, GO:0005634=PMID:20870947, GO:0090267=PMID:20870947, GO:0031145=Reactome:REACT_6850, GO:0042803=PMID:18022367, GO:0005829=Reactome:REACT_150414, GO:0005643=PMID:18981471, GO:0000087=Reactome:REACT_910, GO:0043066=PMID:20870947, GO:0042177=PMID:11459825, GO:0060564=PMID:11459825, GO:0051436=Reactome:REACT_1041, GO:0051439=Reactome:REACT_6837, GO:0000922=GO_REF:0000039, GO:0000070=GO_REF:0000019, GO:0000777=GO_REF:0000039, GO:0000776=PMID:20133940, GO:0000075=Reactome:REACT_1538, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q13257 Mitotic spindle assembly checkpoint protein MAD2A protein 20081114 {GO:0005515=IPI, GO:0072686=IDA, GO:0000236=TAS, GO:0007094=TAS, GO:0048471=IDA, GO:0007093=IDA, GO:0005634=IDA, GO:0090267=IMP, GO:0031145=TAS, GO:0042803=IPI, GO:0005829=TAS, GO:0005643=IDA, GO:0000087=TAS, GO:0043066=IMP, GO:0042177=IDA, GO:0060564=IDA, GO:0051436=TAS, GO:0051439=TAS, GO:0000922=IEA, GO:0000070=IEA, GO:0000777=IEA, GO:0000776=IDA, GO:0000075=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle checkpoint, cell division, mitotic anaphase, mitotic cell cycle, mitotic cell cycle checkpoint, mitotic prometaphase, mitotic sister chromatid segregation, mitotic spindle assembly checkpoint, negative regulation of apoptotic process, negative regulation of mitotic anaphase-promoting complex activity, negative regulation of protein catabolic process, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of mitotic cell cycle spindle assembly checkpoint, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle condensed chromosome kinetochore, cytosol, kinetochore, mitotic spindle, nuclear pore, nucleus, perinuclear region of cytoplasm, spindle pole protein binding, protein homodimerization activity Human UniProtKB:P78536 MAD2L1BP IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0005737=PMID:10942595, GO:0007093=PMID:18022368, GO:0007096=PMID:12456649, GO:0005819=GO_REF:0000039, GO:0005634=PMID:10942595} Q15013 MAD2L1-binding protein protein 20130415 {GO:0005515=IPI, GO:0005737=IDA, GO:0007093=IMP, GO:0007096=IMP, GO:0005819=IEA, GO:0005634=IDA} mitotic cell cycle checkpoint, regulation of exit from mitosis cytoplasm, nucleus, spindle protein binding Human UniProtKB:Q15645 MAD2L2 BHF-UCL UniProtKB {GO:0005515=PMID:10527948, GO:0007094=PMID:10366450, GO:0005634=PMID:19443654, GO:2000048=PMID:19443654, GO:0010719=PMID:19443654, GO:2000678=PMID:19443654, GO:0001558=PMID:15988022, GO:0043433=PMID:19443654, GO:0006302=PMID:15988022, GO:0005737=GO_REF:0000039, GO:0033138=PMID:17296730, GO:0010944=PMID:19443654, GO:0005680=PMID:11459825, GO:0007015=PMID:19443654, GO:0016035=PMID:20164194, GO:0008432=PMID:17296730, GO:0090090=PMID:19443654, GO:0001102=PMID:19443654, GO:0042177=PMID:11459826, GO:0005819=PMID:21063390, GO:0060564=PMID:11459826, GO:0000122=PMID:19443654, GO:0006351=GO_REF:0000037, GO:0042772=PMID:17296730, GO:0007067=GO_REF:0000037, GO:0006281=Reactome:REACT_216, GO:0005654=Reactome:REACT_1918, GO:0045893=PMID:17296730, GO:0051301=GO_REF:0000037} Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B protein 20121203 {GO:0005515=IPI, GO:0007094=TAS, GO:0005634=IDA, GO:2000048=IMP, GO:0010719=IMP, GO:2000678=IMP, GO:0001558=IGI, GO:0043433=IDA, GO:0006302=IGI, GO:0005737=IEA, GO:0033138=IDA, GO:0010944=IMP, GO:0005680=IDA, GO:0007015=IMP, GO:0016035=IDA, GO:0008432=IDA, GO:0090090=IMP, GO:0001102=IPI, GO:0042177=IDA, GO:0005819=IDA, GO:0060564=IDA, GO:0000122=IDA, GO:0006351=IEA, GO:0042772=IDA, GO:0007067=IEA, GO:0006281=TAS, GO:0005654=TAS, GO:0045893=IMP, GO:0051301=IEA} DNA damage response, signal transduction resulting in transcription, DNA repair, actin filament organization, cell division, double-strand break repair, mitosis, mitotic spindle assembly checkpoint, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cell-cell adhesion mediated by cadherin, negative regulation of epithelial to mesenchymal transition, negative regulation of mitotic anaphase-promoting complex activity, negative regulation of protein catabolic process, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription by competitive promoter binding, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription regulatory region DNA binding, positive regulation of peptidyl-serine phosphorylation, positive regulation of transcription, DNA-dependent, regulation of cell growth, transcription, DNA-dependent anaphase-promoting complex, cytoplasm, nucleoplasm, nucleus, spindle, zeta DNA polymerase complex JUN kinase binding, RNA polymerase II activating transcription factor binding, protein binding Human MADCAM1 InterPro UniProtKB {GO:0007165=PMID:8502297, GO:0006955=PMID:8502297, GO:0005886=Reactome:REACT_11230, GO:0016020=GO_REF:0000002, GO:0030216=GO_REF:0000019, GO:0050776=Reactome:REACT_11152, GO:0007568=GO_REF:0000019, GO:0002687=GO_REF:0000019, GO:0009790=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0050900=GO_REF:0000019, GO:0007155=GO_REF:0000002} Q5UGI7 Mucosal vascular addressin cell adhesion molecule 1 splice variant protein 20130413 {GO:0007165=TAS, GO:0006955=TAS, GO:0005886=TAS, GO:0016020=IEA, GO:0030216=IEA, GO:0050776=TAS, GO:0007568=IEA, GO:0002687=IEA, GO:0009790=IEA, GO:0016021=IEA, GO:0050900=IEA, GO:0007155=IEA} aging, cell adhesion, embryo development, immune response, keratinocyte differentiation, leukocyte migration, positive regulation of leukocyte migration, regulation of immune response, signal transduction integral to membrane, membrane, plasma membrane Human InterPro:IPR015169 MADD HPA UniProtKB {GO:0005515=PMID:16273344, GO:0017112=PMID:20937701, GO:0000187=PMID:9115275, GO:0005737=GO_REF:0000039, GO:0005886=GO_REF:0000052, GO:0051726=PMID:14735464, GO:0006915=GO_REF:0000037, GO:0042981=PMID:14735464, GO:0005123=PMID:9115275, GO:0016021=PMID:8988362, GO:0030295=PMID:9115275, GO:0007166=PMID:9115275} Q8WXG6 MAP kinase-activating death domain protein protein 20111111 {GO:0005515=IPI, GO:0017112=IDA, GO:0000187=IMP, GO:0005737=IEA, GO:0005886=IDA, GO:0051726=IMP, GO:0006915=IEA, GO:0042981=IMP, GO:0005123=TAS, GO:0016021=IDA, GO:0030295=TAS, GO:0007166=TAS} activation of MAPK activity, apoptotic process, cell surface receptor signaling pathway, regulation of apoptotic process, regulation of cell cycle cytoplasm, integral to membrane, plasma membrane Rab guanyl-nucleotide exchange factor activity, death receptor binding, protein binding, protein kinase activator activity Human MAEA HPA UniProtKB {GO:0005826=PMID:16510120, GO:0005819=PMID:16510120, GO:0003779=PMID:16510120, GO:0005634=GO_REF:0000052, GO:0015629=GO_REF:0000019, GO:0016363=PMID:16510120, GO:0007346=PMID:16510120, GO:0007049=GO_REF:0000037, GO:0043249=GO_REF:0000037, GO:0005887=PMID:9763581, GO:0048822=GO_REF:0000019, GO:0007010=GO_REF:0000019, GO:0007155=PMID:9763581, GO:0005856=PMID:16510120, GO:0033033=PMID:9763581, GO:0051301=GO_REF:0000037} Q7L5Y9 Macrophage erythroblast attacher protein 20110516 {GO:0005826=IDA, GO:0005819=IDA, GO:0003779=IDA, GO:0005634=IDA, GO:0015629=IEA, GO:0016363=IDA, GO:0007346=NAS, GO:0007049=IEA, GO:0043249=IEA, GO:0005887=IDA, GO:0048822=IEA, GO:0007010=IEA, GO:0007155=IDA, GO:0005856=IDA, GO:0033033=IDA, GO:0051301=IEA} cell adhesion, cell cycle, cell division, cytoskeleton organization, enucleate erythrocyte development, erythrocyte maturation, negative regulation of myeloid cell apoptotic process, regulation of mitotic cell cycle actin cytoskeleton, actomyosin contractile ring, cytoskeleton, integral to plasma membrane, nuclear matrix, nucleus, spindle actin binding Human MAF PINC UniProtKB {GO:0048839=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0070306=GO_REF:0000019, GO:0006366=PMID:9616139, GO:0005634=GO_REF:0000039, GO:0032330=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0001816=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0048468=GO_REF:0000019, GO:0000785=PMID:9616139} O75444 Transcription factor Maf protein 20030904 {GO:0048839=IEA, GO:0003700=IEA, GO:0070306=IEA, GO:0006366=TAS, GO:0005634=IEA, GO:0032330=IEA, GO:0000122=IEA, GO:0001816=IEA, GO:0043565=IEA, GO:0005737=IEA, GO:0045944=IEA, GO:0048468=IEA, GO:0000785=TAS} cell development, cytokine production, inner ear development, lens fiber cell differentiation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter, regulation of chondrocyte differentiation, transcription from RNA polymerase II promoter chromatin, cytoplasm, nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human MAF1 LIFEdb UniProtKB {GO:0030424=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0005634=PMID:20233713, GO:0060077=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0005829=GO_REF:0000019, GO:0005622=GO_REF:0000054, GO:0005737=PMID:20233713, GO:0016480=PMID:20233713, GO:0001032=PMID:20233713, GO:0001030=PMID:20233713, GO:0001031=PMID:20233713} Q9H063 Repressor of RNA polymerase III transcription MAF1 homolog protein 20100607 {GO:0030424=IEA, GO:0005886=IEA, GO:0005634=IDA, GO:0060077=IEA, GO:0030425=IEA, GO:0006351=IEA, GO:0005829=IEA, GO:0005622=IDA, GO:0005737=IDA, GO:0016480=IDA, GO:0001032=IDA, GO:0001030=IDA, GO:0001031=IDA} negative regulation of transcription from RNA polymerase III promoter, transcription, DNA-dependent axon, cytoplasm, cytosol, dendrite, inhibitory synapse, intracellular, nucleus, plasma membrane RNA polymerase III type 1 promoter DNA binding, RNA polymerase III type 2 promoter DNA binding, RNA polymerase III type 3 promoter DNA binding Human MAFA BHF-UCL UniProtKB {GO:0043565=GO_REF:0000002, GO:0006355=PMID:12368292, GO:0003700=PMID:17941991, GO:0007263=PMID:17941991, GO:0046982=PMID:12368292, GO:0045944=GO_REF:0000019, GO:0005634=PMID:12368292, GO:0030073=PMID:17941991, GO:0003677=PMID:12368292, GO:0042803=PMID:12368292, GO:0006351=GO_REF:0000037, GO:0009749=PMID:12368292} Q8NHW3 Transcription factor MafA protein 20080228 {GO:0043565=IEA, GO:0006355=TAS, GO:0003700=TAS, GO:0007263=IDA, GO:0046982=NAS, GO:0045944=IEA, GO:0005634=IDA, GO:0030073=IDA, GO:0003677=IDA, GO:0042803=TAS, GO:0006351=IEA, GO:0009749=IDA} insulin secretion, nitric oxide mediated signal transduction, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, response to glucose stimulus, transcription, DNA-dependent nucleus DNA binding, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human MAFB PINC UniProtKB {GO:0005515=PMID:10698492, GO:0005667=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0042472=GO_REF:0000019, GO:0007379=GO_REF:0000019, GO:0007585=GO_REF:0000019, GO:0005634=PMID:8001130, GO:0006351=GO_REF:0000037, GO:0007423=PMID:8001130, GO:0043565=GO_REF:0000002, GO:0021572=GO_REF:0000019, GO:0021571=GO_REF:0000019, GO:0045647=PMID:8620536, GO:0035284=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0008134=PMID:10698492} Q9Y5Q3 Transcription factor MafB protein 20030904 {GO:0005515=IPI, GO:0005667=IEA, GO:0003700=IEA, GO:0042472=IEA, GO:0007379=IEA, GO:0007585=IEA, GO:0005634=TAS, GO:0006351=IEA, GO:0007423=TAS, GO:0043565=IEA, GO:0021572=IEA, GO:0021571=IEA, GO:0045647=IDA, GO:0035284=IEA, GO:0045944=IEA, GO:0008134=IDA} brain segmentation, inner ear morphogenesis, negative regulation of erythrocyte differentiation, positive regulation of transcription from RNA polymerase II promoter, respiratory gaseous exchange, rhombomere 5 development, rhombomere 6 development, segment specification, sensory organ development, transcription, DNA-dependent nucleus, transcription factor complex protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human MAFF Reactome UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0007567=PMID:10527846, GO:0006366=PMID:10527846, GO:0007596=Reactome:REACT_604, GO:0005654=Reactome:REACT_25340, GO:0005634=GO_REF:0000002, GO:0045604=GO_REF:0000019, GO:0001701=GO_REF:0000019} Q9ULX9 Transcription factor MafF protein 20130301 {GO:0043565=IEA, GO:0003700=IEA, GO:0007567=TAS, GO:0006366=TAS, GO:0007596=TAS, GO:0005654=TAS, GO:0005634=IEA, GO:0045604=IEA, GO:0001701=IEA} blood coagulation, in utero embryonic development, parturition, regulation of epidermal cell differentiation, transcription from RNA polymerase II promoter nucleoplasm, nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human MAFG Reactome UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0042127=GO_REF:0000019, GO:0030641=GO_REF:0000019, GO:0005654=Reactome:REACT_25340, GO:0030534=GO_REF:0000019, GO:0005634=GO_REF:0000002, GO:0045604=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0006351=GO_REF:0000037} O15525 Transcription factor MafG protein 20130301 {GO:0043565=IEA, GO:0003700=IEA, GO:0007596=TAS, GO:0042127=IEA, GO:0030641=IEA, GO:0005654=TAS, GO:0030534=IEA, GO:0005634=IEA, GO:0045604=IEA, GO:0001701=IEA, GO:0006351=IEA} adult behavior, blood coagulation, in utero embryonic development, regulation of cell proliferation, regulation of cellular pH, regulation of epidermal cell differentiation, transcription, DNA-dependent nucleoplasm, nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human MAFK Reactome UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0005654=Reactome:REACT_25340, GO:0006351=GO_REF:0000037} O60675 Transcription factor MafK protein 20130301 {GO:0043565=IEA, GO:0003700=IEA, GO:0007596=TAS, GO:0005654=TAS, GO:0006351=IEA} blood coagulation, transcription, DNA-dependent nucleoplasm sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human MAG Reactome UniProtKB {GO:0043220=GO_REF:0000019, GO:0048011=Reactome:REACT_13776, GO:0005886=Reactome:REACT_16975, GO:0007596=Reactome:REACT_604, GO:0033270=GO_REF:0000019, GO:0050771=Reactome:REACT_13815, GO:0016021=GO_REF:0000037, GO:0050900=Reactome:REACT_12051, GO:0007155=GO_REF:0000037, GO:0050770=Reactome:REACT_13620} P20916 Myelin-associated glycoprotein protein 20130301 {GO:0043220=IEA, GO:0048011=TAS, GO:0005886=TAS, GO:0007596=TAS, GO:0033270=IEA, GO:0050771=TAS, GO:0016021=IEA, GO:0050900=TAS, GO:0007155=IEA, GO:0050770=TAS} blood coagulation, cell adhesion, leukocyte migration, negative regulation of axonogenesis, neurotrophin TRK receptor signaling pathway, regulation of axonogenesis Schmidt-Lanterman incisure, integral to membrane, paranode region of axon, plasma membrane Human MAGEA1 IntAct UniProtKB {GO:0005515=PMID:21364888, GO:0045746=PMID:15316101, GO:0005737=PMID:15316101, GO:0005886=PMID:1840703, GO:0042826=PMID:15316101, GO:0005634=PMID:15316101, GO:0000122=PMID:15316101, GO:0006351=GO_REF:0000037} P43355 Melanoma-associated antigen 1 protein 20130415 {GO:0005515=IPI, GO:0045746=IDA, GO:0005737=IDA, GO:0005886=TAS, GO:0042826=IDA, GO:0005634=IDA, GO:0000122=IDA, GO:0006351=IEA} negative regulation of Notch signaling pathway, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, nucleus, plasma membrane histone deacetylase binding, protein binding Human UniProtKB:Q8N140 MAGEA10 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039} P43363 Melanoma-associated antigen 10 protein 20130413 {GO:0005634=IEA} nucleus Human UniProtKB-SubCell:SL-0191 MAGEA11 HPA UniProtKB {GO:0005515=PMID:16189514, GO:0005737=GO_REF:0000052, GO:0005634=GO_REF:0000052} P43364 Melanoma-associated antigen 11 protein 20111111 {GO:0005515=IPI, GO:0005737=IDA, GO:0005634=IDA} cytoplasm, nucleus protein binding Human MAGEA12 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} P43365 Melanoma-associated antigen 12 protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human MAGEA2 IntAct UniProtKB {GO:0005515=PMID:20864041, GO:0042826=PMID:16847267, GO:0005634=PMID:16847267, GO:0000122=PMID:16847267, GO:0006351=GO_REF:0000037, GO:0072331=PMID:16847267, GO:0016605=PMID:22117195, GO:0070491=PMID:16847267, GO:0051443=PMID:20864041, GO:1901984=PMID:22117195, GO:0033234=PMID:22117195, GO:0044257=PMID:20864041, GO:0031625=PMID:20864041, GO:0090398=PMID:22117195} P43356 Melanoma-associated antigen 2 protein 20130415 {GO:0005515=IPI, GO:0042826=IDA, GO:0005634=IDA, GO:0000122=IDA, GO:0006351=IEA, GO:0072331=IDA, GO:0016605=IDA, GO:0070491=IDA, GO:0051443=IMP, GO:1901984=IDA, GO:0033234=IDA, GO:0044257=IMP, GO:0031625=IDA, GO:0090398=IDA} cellular protein catabolic process, cellular senescence, negative regulation of protein acetylation, negative regulation of protein sumoylation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of ubiquitin-protein ligase activity, signal transduction by p53 class mediator, transcription, DNA-dependent PML body, nucleus histone deacetylase binding, protein binding, repressing transcription factor binding, ubiquitin protein ligase binding Human UniProtKB:P62256 MAGEA2B null null {} null null null null {} null null null MAGEA3 IntAct UniProtKB {GO:0005515=PMID:21277283} P43357 Melanoma-associated antigen 3 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:Q13263 MAGEA4 IntAct UniProtKB {GO:0005515=PMID:12525503, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} P43358 Melanoma-associated antigen 4 protein 20130415 {GO:0005515=IPI, GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function, protein binding Human UniProtKB:O75832 MAGEA6 IntAct UniProtKB {GO:0005515=PMID:20864041, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} P43360 Melanoma-associated antigen 6 protein 20130415 {GO:0005515=IPI, GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function, protein binding Human UniProtKB:Q13263 MAGEA8 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} P43361 Melanoma-associated antigen 8 protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human MAGEA9 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} P43362 Melanoma-associated antigen 9 protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human MAGEB1 null null {} null null null null {} null null null MAGEB10 null null {} null null null null {} null null null MAGEB18 IntAct UniProtKB {GO:0005515=PMID:20864041, GO:0005737=GO_REF:0000019} Q96M61 Melanoma-associated antigen B18 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA} cytoplasm protein binding Human UniProtKB:Q8TBB1 MAGEB2 null null {} null null null null {} null null null MAGEB4 null null {} null null null null {} null null null MAGEB6 IntAct UniProtKB {GO:0005515=PMID:23275563, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q8N7X4 Melanoma-associated antigen B6 protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function, protein binding Human UniProtKB:P42858 MAGEC1 null null {} null null null null {} null null null MAGEC2 IntAct UniProtKB {GO:0005515=PMID:20864041, GO:0005737=PMID:12920247, GO:0051443=PMID:20864041, GO:0005634=PMID:12920247, GO:0044257=PMID:20864041, GO:0031625=PMID:20864041} Q9UBF1 Melanoma-associated antigen C2 protein 20130415 {GO:0005515=IPI, GO:0005737=IDA, GO:0051443=IMP, GO:0005634=IDA, GO:0044257=IMP, GO:0031625=IDA} cellular protein catabolic process, positive regulation of ubiquitin-protein ligase activity cytoplasm, nucleus protein binding, ubiquitin protein ligase binding Human UniProtKB:P62256 MAGED1 Reactome UniProtKB {GO:0005515=PMID:15930293, GO:0048011=Reactome:REACT_13776, GO:0006355=PMID:15930293, GO:0043065=GO_REF:0000019, GO:0006357=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0003713=GO_REF:0000019, GO:0050680=PMID:15930293, GO:0006915=Reactome:REACT_13638, GO:0042981=Reactome:REACT_13648, GO:0097190=Reactome:REACT_13720, GO:0043234=PMID:15930293, GO:0005737=GO_REF:0000039, GO:0043406=GO_REF:0000019, GO:0045893=GO_REF:0000019, GO:0045892=GO_REF:0000019, GO:0090190=GO_REF:0000019} Q9Y5V3 Melanoma-associated antigen D1 protein 20070417 {GO:0005515=IPI, GO:0048011=TAS, GO:0006355=TAS, GO:0043065=IEA, GO:0006357=IEA, GO:0005886=IEA, GO:0003713=IEA, GO:0050680=IDA, GO:0006915=TAS, GO:0042981=TAS, GO:0097190=TAS, GO:0043234=IDA, GO:0005737=IEA, GO:0043406=IEA, GO:0045893=IEA, GO:0045892=IEA, GO:0090190=IEA} apoptotic process, apoptotic signaling pathway, negative regulation of epithelial cell proliferation, negative regulation of transcription, DNA-dependent, neurotrophin TRK receptor signaling pathway, positive regulation of MAP kinase activity, positive regulation of apoptotic process, positive regulation of branching involved in ureteric bud morphogenesis, positive regulation of transcription, DNA-dependent, regulation of apoptotic process, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent cytoplasm, plasma membrane, protein complex protein binding, transcription coactivator activity Human MAGED2 null null {} null null null null {} null null null MAGED4 null null {} null null null null {} null null null MAGED4B null null {} null null null null {} null null null MAGEE1 IntAct UniProtKB {GO:0005515=PMID:20864041, GO:0008150=GO_REF:0000015, GO:0048471=PMID:14623885, GO:0016010=PMID:14623885, GO:0005886=PMID:14623885, GO:0045211=PMID:14623885, GO:0005634=PMID:14623885, GO:0030425=PMID:14623885} Q9HCI5 Melanoma-associated antigen E1 protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0048471=ISS, GO:0016010=ISS, GO:0005886=ISS, GO:0045211=ISS, GO:0005634=ISS, GO:0030425=ISS} biological_process dendrite, dystrophin-associated glycoprotein complex, nucleus, perinuclear region of cytoplasm, plasma membrane, postsynaptic membrane protein binding Human UniProtKB:Q13263 MAGEF1 null null {} null null null null {} null null null MAGEH1 PINC UniProtKB {GO:0005737=GO_REF:0000019, GO:0006915=PMID:10948432} Q9H213 Melanoma-associated antigen H1 protein 20050308 {GO:0005737=IEA, GO:0006915=TAS} apoptotic process cytoplasm Human MAGEL2 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0006355=GO_REF:0000019, GO:0005575=GO_REF:0000015} Q9UJ55 MAGE-like protein 2 protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0006355=IEA, GO:0005575=ND} biological_process, regulation of transcription, DNA-dependent cellular_component molecular_function Human MAGI1 IntAct UniProtKB {GO:0005515=PMID:14627983, GO:0005737=PMID:16464232, GO:0006461=PMID:9647739, GO:0005886=GO_REF:0000039, GO:0005911=PMID:9647739, GO:0051393=PMID:16464232, GO:0042995=PMID:16464232, GO:0005923=GO_REF:0000039, GO:0007155=PMID:9647739, GO:0008022=PMID:9647739, GO:0005524=GO_REF:0000037, GO:0007166=PMID:9647739} Q96QZ7 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 protein 20130415 {GO:0005515=IPI, GO:0005737=IDA, GO:0006461=NAS, GO:0005886=IEA, GO:0005911=TAS, GO:0051393=IPI, GO:0042995=IDA, GO:0005923=IEA, GO:0007155=TAS, GO:0008022=TAS, GO:0005524=IEA, GO:0007166=TAS} cell adhesion, cell surface receptor signaling pathway, protein complex assembly cell projection, cell-cell junction, cytoplasm, plasma membrane, tight junction ATP binding, alpha-actinin binding, protein C-terminus binding, protein binding Human UniProtKB:O94868 MAGI2 IntAct UniProtKB {GO:0051898=PMID:10760291, GO:0005515=PMID:16316992, GO:0048471=GO_REF:0000024, GO:0008285=GO_REF:0000024, GO:0005886=PMID:10760291, GO:0072015=GO_REF:0000024, GO:0030159=PMID:11526121, GO:0045202=GO_REF:0000024, GO:0005634=PMID:10760291, GO:0046332=GO_REF:0000024, GO:0031697=PMID:11526121, GO:0051291=GO_REF:0000024, GO:0060395=GO_REF:0000024, GO:0005737=PMID:11526121, GO:0070699=GO_REF:0000024, GO:0004871=GO_REF:0000019, GO:0030336=GO_REF:0000024, GO:0003402=PMID:20534871, GO:0019902=PMID:10760291, GO:0014069=GO_REF:0000024, GO:0032926=GO_REF:0000024, GO:0071850=GO_REF:0000024, GO:0036057=GO_REF:0000024, GO:0043113=GO_REF:0000024, GO:0005923=PMID:10760291} Q86UL8 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 protein 20130415 {GO:0051898=IDA, GO:0005515=IPI, GO:0048471=ISS, GO:0008285=ISS, GO:0005886=IDA, GO:0072015=ISS, GO:0030159=IDA, GO:0045202=ISS, GO:0005634=IDA, GO:0046332=ISS, GO:0031697=IPI, GO:0051291=ISS, GO:0060395=ISS, GO:0005737=IDA, GO:0070699=ISS, GO:0004871=IEA, GO:0030336=ISS, GO:0003402=NAS, GO:0019902=IPI, GO:0014069=ISS, GO:0032926=ISS, GO:0071850=ISS, GO:0036057=ISS, GO:0043113=ISS, GO:0005923=IDA} SMAD protein signal transduction, glomerular visceral epithelial cell development, mitotic cell cycle arrest, negative regulation of activin receptor signaling pathway, negative regulation of cell migration, negative regulation of cell proliferation, negative regulation of protein kinase B signaling cascade, planar cell polarity pathway involved in axis elongation, protein heterooligomerization, receptor clustering cytoplasm, nucleus, perinuclear region of cytoplasm, plasma membrane, postsynaptic density, slit diaphragm, synapse, tight junction SMAD binding, beta-1 adrenergic receptor binding, phosphatase binding, protein binding, receptor signaling complex scaffold activity, signal transducer activity, type II activin receptor binding Human UniProtKB:P08588 MAGI3 IntAct UniProtKB {GO:0005515=PMID:16316992, GO:0035556=PMID:10748157, GO:0005109=GO_REF:0000019, GO:0016020=PMID:10748157, GO:0005886=GO_REF:0000039, GO:0019048=GO_REF:0000037, GO:0006915=PMID:10748157, GO:0004385=PMID:10748157, GO:0005634=GO_REF:0000039, GO:0005923=GO_REF:0000039, GO:0043507=GO_REF:0000019, GO:0005524=GO_REF:0000037} Q5TCQ9 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 protein 20130415 {GO:0005515=IPI, GO:0035556=NAS, GO:0005109=IEA, GO:0016020=NAS, GO:0005886=IEA, GO:0019048=IEA, GO:0006915=NAS, GO:0004385=NAS, GO:0005634=IEA, GO:0005923=IEA, GO:0043507=IEA, GO:0005524=IEA} apoptotic process, intracellular signal transduction, positive regulation of JUN kinase activity, virus-host interaction membrane, nucleus, plasma membrane, tight junction ATP binding, frizzled binding, guanylate kinase activity, protein binding Human UniProtKB:P08588 MAGOH IntAct UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:23084401, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0016070=Reactome:REACT_21257, GO:0006366=Reactome:REACT_1366, GO:0016071=Reactome:REACT_20605, GO:0003723=GO_REF:0000037, GO:0031124=Reactome:REACT_1849, GO:0005634=GO_REF:0000029, GO:0071013=PMID:11991638, GO:0006417=GO_REF:0000037, GO:0005829=Reactome:REACT_75910, GO:0006406=Reactome:REACT_1597, GO:0016607=GO_REF:0000039, GO:0000184=Reactome:REACT_75886, GO:0000398=Reactome:REACT_467, GO:0005654=Reactome:REACT_2104, GO:0035145=PMID:16601204} P61326 Protein mago nashi homolog protein 20130415 {GO:0008380=TAS, GO:0005515=IPI, GO:0010467=TAS, GO:0006369=TAS, GO:0016070=TAS, GO:0006366=TAS, GO:0016071=TAS, GO:0003723=IEA, GO:0031124=TAS, GO:0005634=NAS, GO:0071013=IDA, GO:0006417=IEA, GO:0005829=TAS, GO:0006406=TAS, GO:0016607=IEA, GO:0000184=TAS, GO:0000398=TAS, GO:0005654=TAS, GO:0035145=IDA} RNA metabolic process, RNA splicing, gene expression, mRNA 3'-end processing, mRNA export from nucleus, mRNA metabolic process, mRNA splicing, via spliceosome, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, regulation of translation, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter catalytic step 2 spliceosome, cytosol, exon-exon junction complex, nuclear speck, nucleoplasm, nucleus RNA binding, protein binding Human UniProtKB:O15234 MAGOHB UniProtKB UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0051028=GO_REF:0000037} Q96A72 Protein mago nashi homolog 2 protein 20130413 {GO:0008380=IEA, GO:0006397=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0051028=IEA} RNA splicing, mRNA processing, mRNA transport nucleus RNA binding Human UniProtKB-SubCell:SL-0191 MAGT1 HGNC UniProtKB {GO:0015693=PMID:19717468, GO:0050890=PMID:18455129, GO:0005887=PMID:19717468, GO:0015095=PMID:19717468, GO:0006487=PMID:18455129, GO:0008250=PMID:15835887} Q9H0U3 Magnesium transporter protein 1 protein 20061117 {GO:0015693=IMP, GO:0050890=IMP, GO:0005887=NAS, GO:0015095=IMP, GO:0006487=NAS, GO:0008250=IDA} cognition, magnesium ion transport, protein N-linked glycosylation integral to plasma membrane, oligosaccharyltransferase complex magnesium ion transmembrane transporter activity Human MAK UniProtKB UniProtKB {GO:0005515=PMID:21986944, GO:0072686=PMID:21986944, GO:0005813=PMID:21986944, GO:0006355=GO_REF:0000037, GO:0003713=PMID:16951154, GO:0030496=PMID:21986944, GO:0005634=PMID:12084720, GO:0007275=GO_REF:0000037, GO:0007283=PMID:2183027, GO:0045494=GO_REF:0000024, GO:0005524=GO_REF:0000038, GO:0006351=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0001917=PMID:21825139, GO:0005737=GO_REF:0000037, GO:0046777=PMID:21986944, GO:0004672=PMID:2183027, GO:0004674=GO_REF:0000002, GO:0006468=PMID:21986944, GO:0004693=GO_REF:0000003, GO:0001750=GO_REF:0000024} Q8IXN4 Serine/threonine-protein kinase MAK protein 20130413 {GO:0005515=IPI, GO:0072686=IDA, GO:0005813=IDA, GO:0006355=IEA, GO:0003713=IDA, GO:0030496=IDA, GO:0005634=IDA, GO:0007275=IEA, GO:0007283=NAS, GO:0045494=ISS, GO:0005524=IEA, GO:0006351=IEA, GO:0030154=IEA, GO:0001917=IDA, GO:0005737=IEA, GO:0046777=IMP, GO:0004672=NAS, GO:0004674=IEA, GO:0006468=IDA, GO:0004693=IEA, GO:0001750=ISS} cell differentiation, multicellular organismal development, photoreceptor cell maintenance, protein autophosphorylation, protein phosphorylation, regulation of transcription, DNA-dependent, spermatogenesis, transcription, DNA-dependent centrosome, cytoplasm, midbody, mitotic spindle, nucleus, photoreceptor inner segment, photoreceptor outer segment ATP binding, cyclin-dependent protein serine/threonine kinase activity, protein binding, protein kinase activity, protein serine/threonine kinase activity, transcription coactivator activity Human UniProtKB-KW:KW-0067 MAK16 UniProtKB UniProtKB {GO:0005730=GO_REF:0000039} Q9BXY0 Protein MAK16 homolog protein 20130413 {GO:0005730=IEA} nucleolus Human UniProtKB-SubCell:SL-0188 MAL IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0005783=PMID:8132541, GO:0042552=PMID:10428054, GO:0045176=PMID:10739088, GO:0006917=PMID:10366425, GO:0007417=PMID:10739088, GO:0030154=PMID:10739088, GO:0008289=PMID:10739088, GO:0016505=PMID:10366425, GO:0016324=PMID:10739088, GO:0005887=PMID:9003426, GO:0045121=PMID:12153479, GO:0001766=PMID:12153479, GO:0019911=PMID:12153479, GO:0015267=PMID:3494249, GO:0005768=PMID:9003426, GO:0019898=GO_REF:0000019} P21145 Myelin and lymphocyte protein protein 20130415 {GO:0005515=IPI, GO:0005783=IDA, GO:0042552=TAS, GO:0045176=TAS, GO:0006917=NAS, GO:0007417=TAS, GO:0030154=TAS, GO:0008289=TAS, GO:0016505=NAS, GO:0016324=TAS, GO:0005887=TAS, GO:0045121=IDA, GO:0001766=TAS, GO:0019911=IDA, GO:0015267=TAS, GO:0005768=TAS, GO:0019898=IEA} apical protein localization, cell differentiation, central nervous system development, induction of apoptosis, membrane raft polarization, myelination apical plasma membrane, endoplasmic reticulum, endosome, extrinsic to membrane, integral to plasma membrane, membrane raft apoptotic protease activator activity, channel activity, lipid binding, protein binding, structural constituent of myelin sheath Human UniProtKB:Q93009 MAL2 UniProtKB UniProtKB {GO:0005515=PMID:12963375, GO:0048471=GO_REF:0000039, GO:0016324=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0012505=GO_REF:0000039} Q969L2 Protein MAL2 protein 20060116 {GO:0005515=IPI, GO:0048471=IEA, GO:0016324=IEA, GO:0016021=IEA, GO:0012505=IEA} apical plasma membrane, endomembrane system, integral to membrane, perinuclear region of cytoplasm protein binding Human UniProtKB:O43399-1 MALL HGNC UniProtKB {GO:0005515=PMID:11294831, GO:0042632=PMID:11294831, GO:0005886=PMID:11294831, GO:0000139=PMID:11294831, GO:0030136=PMID:11294831, GO:0016023=PMID:11294831, GO:0045121=PMID:11294831, GO:0016021=GO_REF:0000029} Q13021 MAL-like protein protein 20051102 {GO:0005515=IPI, GO:0042632=NAS, GO:0005886=IDA, GO:0000139=IDA, GO:0030136=IDA, GO:0016023=IDA, GO:0045121=IDA, GO:0016021=NAS} cholesterol homeostasis Golgi membrane, clathrin-coated vesicle, cytoplasmic membrane-bounded vesicle, integral to membrane, membrane raft, plasma membrane protein binding Human MALT1 GOC UniProtKB {GO:0005515=PMID:18223652, GO:0050852=Reactome:REACT_12526, GO:0048471=GO_REF:0000039, GO:0004842=PMID:14695475, GO:0016567=PMID:15125833, GO:0005886=Reactome:REACT_118777, GO:0050856=GO_REF:0000019, GO:0009620=GO_REF:0000019, GO:0002237=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0002020=GO_REF:0000019, GO:0043621=PMID:15125833, GO:0051259=PMID:15125833, GO:0005829=Reactome:REACT_118777, GO:0005737=GO_REF:0000052, GO:0051092=PMID:18223652, GO:0042098=GO_REF:0000019, GO:0031398=PMID:18223652, GO:0006508=PMID:18223652, GO:0001923=GO_REF:0000019, GO:0004871=PMID:12761501, GO:0043123=PMID:12761501, GO:0051168=PMID:16123224, GO:0043066=PMID:11090634, GO:0007250=PMID:15125833, GO:0032449=PMID:15125833, GO:0032743=PMID:15125833, GO:0005730=GO_REF:0000052, GO:0042981=PMID:12819136, GO:0006952=PMID:10523859, GO:0002726=PMID:15125833, GO:0004197=PMID:11090634, GO:0043234=PMID:15125833, GO:0019209=PMID:15125833, GO:0045087=GO_REF:0000019, GO:0050870=PMID:15125833, GO:0008233=PMID:18223652} Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 protein 20130413 {GO:0005515=IPI, GO:0050852=TAS, GO:0048471=IEA, GO:0004842=IDA, GO:0016567=IDA, GO:0005886=TAS, GO:0050856=IEA, GO:0009620=IEA, GO:0002237=IEA, GO:0005634=IDA, GO:0002020=IEA, GO:0043621=IPI, GO:0051259=IDA, GO:0005829=TAS, GO:0005737=IDA, GO:0051092=IMP, GO:0042098=IEA, GO:0031398=NAS, GO:0006508=IDA, GO:0001923=IEA, GO:0004871=IMP, GO:0043123=IMP, GO:0051168=IDA, GO:0043066=NAS, GO:0007250=IMP, GO:0032449=NAS, GO:0032743=IMP, GO:0005730=IDA, GO:0042981=IDA, GO:0006952=NAS, GO:0002726=IMP, GO:0004197=NAS, GO:0043234=IDA, GO:0019209=IMP, GO:0045087=IEA, GO:0050870=IC, GO:0008233=IDA} B-1 B cell differentiation, T cell proliferation, T cell receptor signaling pathway, activation of NF-kappaB-inducing kinase activity, defense response, innate immune response, negative regulation of apoptotic process, nuclear export, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of T cell activation, positive regulation of T cell cytokine production, positive regulation of interleukin-2 production, positive regulation of protein ubiquitination, protein oligomerization, protein ubiquitination, proteolysis, regulation of T cell receptor signaling pathway, regulation of apoptotic process, response to fungus, response to molecule of bacterial origin CBM complex, cytoplasm, cytosol, nucleolus, nucleus, perinuclear region of cytoplasm, plasma membrane, protein complex cysteine-type endopeptidase activity, kinase activator activity, peptidase activity, protease binding, protein binding, protein self-association, signal transducer activity, ubiquitin-protein ligase activity Human MAML1 HPA UniProtKB {GO:0005515=PMID:16510869, GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_14835, GO:0019901=PMID:15546612, GO:0003713=PMID:11101851, GO:0005730=GO_REF:0000052, GO:0010831=PMID:16510869, GO:0005634=GO_REF:0000052, GO:0003162=GO_REF:0000024, GO:0043231=GO_REF:0000052, GO:0002193=PMID:16510869, GO:0060928=GO_REF:0000024, GO:0016607=GO_REF:0000039, GO:0007219=Reactome:REACT_118859, GO:0045944=PMID:16510869, GO:0042605=PMID:17317671, GO:0006468=PMID:16510869, GO:0005654=Reactome:REACT_160309, GO:0045445=GO_REF:0000019} Q92585 Mastermind-like protein 1 protein 20111111 {GO:0005515=IPI, GO:0010467=TAS, GO:0006367=TAS, GO:0019901=IPI, GO:0003713=IDA, GO:0005730=IDA, GO:0010831=IGI, GO:0005634=IDA, GO:0003162=ISS, GO:0043231=IDA, GO:0002193=IDA, GO:0060928=ISS, GO:0016607=IEA, GO:0007219=TAS, GO:0045944=IDA, GO:0042605=IPI, GO:0006468=IDA, GO:0005654=TAS, GO:0045445=IEA} Notch signaling pathway, atrioventricular node cell development, atrioventricular node development, gene expression, myoblast differentiation, positive regulation of myotube differentiation, positive regulation of transcription from RNA polymerase II promoter, protein phosphorylation, transcription initiation from RNA polymerase II promoter MAML1-RBP-Jkappa- ICN1 complex, intracellular membrane-bounded organelle, nuclear speck, nucleolus, nucleoplasm, nucleus peptide antigen binding, protein binding, protein kinase binding, transcription coactivator activity Human MAML2 HPA UniProtKB {GO:0010467=Reactome:REACT_71, GO:0005794=GO_REF:0000052, GO:0006367=Reactome:REACT_14835, GO:0007219=Reactome:REACT_118859, GO:0016607=GO_REF:0000039, GO:0045944=PMID:12370315, GO:0003713=PMID:12370315, GO:0005654=Reactome:REACT_160309, GO:0005634=GO_REF:0000052} Q8IZL2 Mastermind-like protein 2 protein 20111111 {GO:0010467=TAS, GO:0005794=IDA, GO:0006367=TAS, GO:0007219=TAS, GO:0016607=IEA, GO:0045944=IDA, GO:0003713=IDA, GO:0005654=TAS, GO:0005634=IDA} Notch signaling pathway, gene expression, positive regulation of transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter Golgi apparatus, nuclear speck, nucleoplasm, nucleus transcription coactivator activity Human MAML3 HPA UniProtKB {GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_14835, GO:0016607=GO_REF:0000039, GO:0007219=Reactome:REACT_118859, GO:0045944=PMID:12370315, GO:0003713=PMID:12370315, GO:0005730=GO_REF:0000052, GO:0005654=Reactome:REACT_160309, GO:0005634=GO_REF:0000052} Q96JK9 Mastermind-like protein 3 protein 20111111 {GO:0010467=TAS, GO:0006367=TAS, GO:0016607=IEA, GO:0007219=TAS, GO:0045944=IDA, GO:0003713=IDA, GO:0005730=IDA, GO:0005654=TAS, GO:0005634=IDA} Notch signaling pathway, gene expression, positive regulation of transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter nuclear speck, nucleolus, nucleoplasm, nucleus transcription coactivator activity NOT Human MAMSTR UniProtKB UniProtKB {GO:0001076=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0010831=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002} Q6ZN01 MEF2-activating motif and SAP domain-containing transcriptional regulator protein 20130413 {GO:0001076=IEA, GO:0045944=IEA, GO:0010831=IEA, GO:0005634=IEA, GO:0003676=IEA} positive regulation of myotube differentiation, positive regulation of transcription from RNA polymerase II promoter nucleus RNA polymerase II transcription factor binding transcription factor activity, nucleic acid binding Human UniProtKB-SubCell:SL-0191 MAN1A2 InterPro UniProtKB {GO:0005794=GO_REF:0000052, GO:0007585=GO_REF:0000019, GO:0048286=GO_REF:0000019, GO:0004571=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0016020=GO_REF:0000002, GO:0000139=Reactome:REACT_25341, GO:0006491=PMID:9592125, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0018279=Reactome:REACT_22426, GO:0043687=Reactome:REACT_22161} Q5T9E3 Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB protein 20130413 {GO:0005794=IDA, GO:0007585=IEA, GO:0048286=IEA, GO:0004571=IEA, GO:0005509=IEA, GO:0005730=IDA, GO:0016020=IEA, GO:0000139=TAS, GO:0006491=TAS, GO:0016021=IEA, GO:0044267=TAS, GO:0018279=TAS, GO:0043687=TAS} N-glycan processing, cellular protein metabolic process, lung alveolus development, post-translational protein modification, protein N-linked glycosylation via asparagine, respiratory gaseous exchange Golgi apparatus, Golgi membrane, integral to membrane, membrane, nucleolus calcium ion binding, mannosyl-oligosaccharide 1,2-alpha-mannosidase activity Human InterPro:IPR001382 MAN1B1 Reactome UniProtKB {GO:0009311=PMID:10409699, GO:0005783=PMID:18003979, GO:0005509=PMID:10521544, GO:0004571=PMID:12090241, GO:0044322=Reactome:REACT_25313, GO:0030433=PMID:18003979, GO:0016020=PMID:18003979, GO:0006457=Reactome:REACT_23878, GO:0005789=GO_REF:0000039, GO:0006487=PMID:10521544, GO:0016021=PMID:10521544, GO:0044267=Reactome:REACT_17015, GO:0018279=Reactome:REACT_22426, GO:0043687=Reactome:REACT_22161} Q9UKM7 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase protein 20100810 {GO:0009311=TAS, GO:0005783=IDA, GO:0005509=TAS, GO:0004571=IDA, GO:0044322=TAS, GO:0030433=IMP, GO:0016020=IDA, GO:0006457=TAS, GO:0005789=IEA, GO:0006487=NAS, GO:0016021=TAS, GO:0044267=TAS, GO:0018279=TAS, GO:0043687=TAS} ER-associated protein catabolic process, cellular protein metabolic process, oligosaccharide metabolic process, post-translational protein modification, protein N-linked glycosylation, protein N-linked glycosylation via asparagine, protein folding endoplasmic reticulum, endoplasmic reticulum membrane, endoplasmic reticulum quality control compartment, integral to membrane, membrane calcium ion binding, mannosyl-oligosaccharide 1,2-alpha-mannosidase activity Human MAN1C1 Reactome UniProtKB {GO:0030173=PMID:10915796, GO:0000139=Reactome:REACT_25341, GO:0016020=GO_REF:0000002, GO:0005509=PMID:10915796, GO:0004571=PMID:10915796, GO:0006487=PMID:10915796, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q9NR34 Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC protein 20130301 {GO:0030173=TAS, GO:0000139=TAS, GO:0016020=IEA, GO:0005509=TAS, GO:0004571=TAS, GO:0006487=TAS, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS} cellular protein metabolic process, post-translational protein modification, protein N-linked glycosylation, protein N-linked glycosylation via asparagine Golgi membrane, integral to Golgi membrane, membrane calcium ion binding, mannosyl-oligosaccharide 1,2-alpha-mannosidase activity Human MAN2A1 Reactome UniProtKB {GO:0004572=GO_REF:0000003, GO:0007585=GO_REF:0000019, GO:0048286=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0016799=GO_REF:0000019, GO:0001889=GO_REF:0000019, GO:0000139=Reactome:REACT_25047, GO:0006491=GO_REF:0000019, GO:0030246=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007005=GO_REF:0000019, GO:0007033=GO_REF:0000019, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426, GO:0006013=GO_REF:0000002} Q16706 Alpha-mannosidase 2 protein 20101004 {GO:0004572=IEA, GO:0007585=IEA, GO:0048286=IEA, GO:0001701=IEA, GO:0016799=IEA, GO:0001889=IEA, GO:0000139=TAS, GO:0006491=IEA, GO:0030246=IEA, GO:0008270=IEA, GO:0016021=IEA, GO:0007005=IEA, GO:0007033=IEA, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS, GO:0006013=IEA} N-glycan processing, cellular protein metabolic process, in utero embryonic development, liver development, lung alveolus development, mannose metabolic process, mitochondrion organization, post-translational protein modification, protein N-linked glycosylation via asparagine, respiratory gaseous exchange, vacuole organization Golgi membrane, integral to membrane carbohydrate binding, hydrolase activity, hydrolyzing N-glycosyl compounds, mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity, zinc ion binding Human MAN2A2 Reactome UniProtKB {GO:0004572=GO_REF:0000029, GO:0005975=GO_REF:0000029, GO:0015923=GO_REF:0000019, GO:0016799=GO_REF:0000019, GO:0000139=Reactome:REACT_25047, GO:0030246=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0004559=GO_REF:0000002, GO:0006013=GO_REF:0000002, GO:0018279=Reactome:REACT_22426, GO:0043687=Reactome:REACT_22161} P49641 Alpha-mannosidase 2x protein 20101004 {GO:0004572=NAS, GO:0005975=NAS, GO:0015923=IEA, GO:0016799=IEA, GO:0000139=TAS, GO:0030246=IEA, GO:0008270=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0004559=IEA, GO:0006013=IEA, GO:0018279=TAS, GO:0043687=TAS} carbohydrate metabolic process, cellular protein metabolic process, mannose metabolic process, post-translational protein modification, protein N-linked glycosylation via asparagine Golgi membrane, integral to membrane alpha-mannosidase activity, carbohydrate binding, hydrolase activity, hydrolyzing N-glycosyl compounds, mannosidase activity, mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity, zinc ion binding Human MAN2B1 PINC UniProtKB {GO:0005975=GO_REF:0000002, GO:0006517=PMID:8910458, GO:0030246=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0015923=GO_REF:0000002, GO:0005764=GO_REF:0000039, GO:0006464=PMID:8910458, GO:0004559=GO_REF:0000003, GO:0006013=GO_REF:0000002} O00754 Lysosomal alpha-mannosidase protein 20030904 {GO:0005975=IEA, GO:0006517=TAS, GO:0030246=IEA, GO:0008270=IEA, GO:0015923=IEA, GO:0005764=IEA, GO:0006464=IDA, GO:0004559=IEA, GO:0006013=IEA} carbohydrate metabolic process, cellular protein modification process, mannose metabolic process, protein deglycosylation lysosome alpha-mannosidase activity, carbohydrate binding, mannosidase activity, zinc ion binding Human MAN2B2 UniProtKB UniProtKB {GO:0030246=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0005764=GO_REF:0000019, GO:0004559=GO_REF:0000003, GO:0006013=GO_REF:0000019} Q9Y2E5 Epididymis-specific alpha-mannosidase protein 20130413 {GO:0030246=IEA, GO:0005576=IEA, GO:0008270=IEA, GO:0005764=IEA, GO:0004559=IEA, GO:0006013=IEA} mannose metabolic process extracellular region, lysosome alpha-mannosidase activity, carbohydrate binding, zinc ion binding Human UniProtKB-SubCell:SL-0243 MAN2C1 UniProtKB UniProtKB {GO:0030246=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0004559=GO_REF:0000003, GO:0006013=GO_REF:0000002} Q9NTJ4 Alpha-mannosidase 2C1 protein 20130413 {GO:0030246=IEA, GO:0008270=IEA, GO:0004559=IEA, GO:0006013=IEA} mannose metabolic process alpha-mannosidase activity, carbohydrate binding, zinc ion binding Human EC:3.2.1.24 MANBAL UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9NQG1 Protein MANBAL protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 MANEA HPA UniProtKB {GO:0005794=GO_REF:0000052, GO:0000139=Reactome:REACT_25136, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0004569=GO_REF:0000003, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q5SRI9 Glycoprotein endo-alpha-1,2-mannosidase protein 20080205 {GO:0005794=IDA, GO:0000139=TAS, GO:0016021=IEA, GO:0044267=TAS, GO:0004569=IEA, GO:0043687=TAS, GO:0018279=TAS} cellular protein metabolic process, post-translational protein modification, protein N-linked glycosylation via asparagine Golgi apparatus, Golgi membrane, integral to membrane glycoprotein endo-alpha-1,2-mannosidase activity Human MANF UniProtKB UniProtKB {GO:0006986=GO_REF:0000037, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0048471=GO_REF:0000019, GO:0002014=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0005615=GO_REF:0000019, GO:0008083=GO_REF:0000037} P55145 Mesencephalic astrocyte-derived neurotrophic factor protein 20061026 {GO:0006986=IEA, GO:0008150=ND, GO:0003674=ND, GO:0048471=IEA, GO:0002014=IEA, GO:0005575=ND, GO:0005615=IEA, GO:0008083=IEA} biological_process, response to unfolded protein, vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure cellular_component, extracellular space, perinuclear region of cytoplasm growth factor activity, molecular_function Human MAOA Reactome UniProtKB {GO:0008131=Reactome:REACT_15485, GO:0006805=Reactome:REACT_13705, GO:0007268=Reactome:REACT_13685, GO:0007610=PMID:8211186, GO:0042420=GO_REF:0000019, GO:0005741=Reactome:REACT_15485, GO:0044281=Reactome:REACT_111217, GO:0042136=Reactome:REACT_13583, GO:0016021=GO_REF:0000037, GO:0042135=GO_REF:0000037, GO:0007269=Reactome:REACT_13723, GO:0006576=PMID:8211186} P21397 "Amine oxidase ""flavin-containing"" A" protein 20130213 {GO:0008131=TAS, GO:0006805=TAS, GO:0007268=TAS, GO:0007610=TAS, GO:0042420=IEA, GO:0005741=TAS, GO:0044281=TAS, GO:0042136=TAS, GO:0016021=IEA, GO:0042135=IEA, GO:0007269=TAS, GO:0006576=TAS} behavior, cellular biogenic amine metabolic process, dopamine catabolic process, neurotransmitter biosynthetic process, neurotransmitter catabolic process, neurotransmitter secretion, small molecule metabolic process, synaptic transmission, xenobiotic metabolic process integral to membrane, mitochondrial outer membrane primary amine oxidase activity Human MAOB Reactome UniProtKB {GO:0051412=GO_REF:0000019, GO:0006805=Reactome:REACT_13705, GO:0042493=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0050660=GO_REF:0000019, GO:0005743=GO_REF:0000019, GO:0009055=PMID:8602220, GO:0009636=GO_REF:0000019, GO:0010269=GO_REF:0000019, GO:0005741=Reactome:REACT_1260, GO:0044281=Reactome:REACT_111217, GO:0005740=PMID:7063850, GO:0010044=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0014063=GO_REF:0000019, GO:0045964=GO_REF:0000019, GO:0008131=Reactome:REACT_1260, GO:0016491=GO_REF:0000002, GO:0032496=GO_REF:0000019, GO:0016021=GO_REF:0000037} P27338 "Amine oxidase ""flavin-containing"" B" protein 20130213 {GO:0051412=IEA, GO:0006805=TAS, GO:0042493=IEA, GO:0045471=IEA, GO:0050660=IEA, GO:0005743=IEA, GO:0009055=TAS, GO:0009636=IEA, GO:0010269=IEA, GO:0005741=TAS, GO:0044281=TAS, GO:0005740=TAS, GO:0010044=IEA, GO:0042803=IEA, GO:0014063=IEA, GO:0045964=IEA, GO:0008131=TAS, GO:0016491=IEA, GO:0032496=IEA, GO:0016021=IEA} negative regulation of serotonin secretion, positive regulation of dopamine metabolic process, response to aluminum ion, response to corticosterone stimulus, response to drug, response to ethanol, response to lipopolysaccharide, response to selenium ion, response to toxic substance, small molecule metabolic process, xenobiotic metabolic process integral to membrane, mitochondrial envelope, mitochondrial inner membrane, mitochondrial outer membrane electron carrier activity, flavin adenine dinucleotide binding, oxidoreductase activity, primary amine oxidase activity, protein homodimerization activity Human MAP1A IntAct UniProtKB {GO:0005515=PMID:12812986, GO:0008017=GO_REF:0000002, GO:0016787=GO_REF:0000002, GO:0005198=PMID:8812494, GO:0005875=PMID:8812494, GO:0007605=GO_REF:0000019, GO:0005874=GO_REF:0000037, GO:0000226=GO_REF:0000002, GO:0005829=GO_REF:0000019} P78559 Microtubule-associated protein 1A protein 20130415 {GO:0005515=IPI, GO:0008017=IEA, GO:0016787=IEA, GO:0005198=NAS, GO:0005875=TAS, GO:0007605=IEA, GO:0005874=IEA, GO:0000226=IEA, GO:0005829=IEA} microtubule cytoskeleton organization, sensory perception of sound cytosol, microtubule, microtubule associated complex hydrolase activity, microtubule binding, protein binding, structural molecule activity Human UniProtKB:Q9NRI5 MAP1B IntAct UniProtKB {GO:0005515=PMID:12147674, GO:0008017=GO_REF:0000002, GO:0032387=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005886=PMID:19567321, GO:0009987=PMID:19567321, GO:0005875=PMID:1881920, GO:0001578=GO_REF:0000019, GO:0005874=GO_REF:0000037, GO:0045773=GO_REF:0000019, GO:0045202=GO_REF:0000039, GO:0000226=GO_REF:0000002, GO:0007409=GO_REF:0000019, GO:0016358=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0016787=GO_REF:0000002, GO:0047497=GO_REF:0000019, GO:0043197=GO_REF:0000039, GO:0005198=PMID:1881920, GO:0061162=GO_REF:0000019} P46821 Microtubule-associated protein 1B protein 20130415 {GO:0005515=IPI, GO:0008017=IEA, GO:0032387=IEA, GO:0030054=IEA, GO:0005886=IDA, GO:0009987=IDA, GO:0005875=TAS, GO:0001578=IEA, GO:0005874=IEA, GO:0045773=IEA, GO:0045202=IEA, GO:0000226=IEA, GO:0007409=IEA, GO:0016358=IEA, GO:0005829=IEA, GO:0016787=IEA, GO:0047497=IEA, GO:0043197=IEA, GO:0005198=NAS, GO:0061162=IEA} axonogenesis, cellular process, dendrite development, establishment of monopolar cell polarity, microtubule bundle formation, microtubule cytoskeleton organization, mitochondrion transport along microtubule, negative regulation of intracellular transport, positive regulation of axon extension cell junction, cytosol, dendritic spine, microtubule, microtubule associated complex, plasma membrane, synapse hydrolase activity, microtubule binding, protein binding, structural molecule activity Human UniProtKB:Q9H2C0 MAP1LC3A IntAct UniProtKB {GO:0005515=PMID:20562859, GO:0005776=PMID:19056683, GO:0000422=PMID:22267086, GO:0005770=GO_REF:0000019, GO:0008429=PMID:16303767, GO:0005874=GO_REF:0000037, GO:0000421=GO_REF:0000039, GO:0031410=GO_REF:0000037, GO:0012505=GO_REF:0000039, GO:0005829=PMID:15187094, GO:0005543=PMID:15187094, GO:0031090=PMID:12740394, GO:0000045=GO_REF:0000024} Q9H492 Microtubule-associated proteins 1A/1B light chain 3A protein 20130415 {GO:0005515=IPI, GO:0005776=IDA, GO:0000422=IGI, GO:0005770=IEA, GO:0008429=IDA, GO:0005874=IEA, GO:0000421=IEA, GO:0031410=IEA, GO:0012505=IEA, GO:0005829=IDA, GO:0005543=IDA, GO:0031090=IDA, GO:0000045=ISS} autophagic vacuole assembly, mitochondrion degradation autophagic vacuole, autophagic vacuole membrane, cytoplasmic vesicle, cytosol, endomembrane system, late endosome, microtubule, organelle membrane phosphatidylethanolamine binding, phospholipid binding, protein binding Human UniProtKB:Q13501 MAP1LC3B IntAct UniProtKB {GO:0005622=GO_REF:0000054, GO:0005515=PMID:20562859, GO:0005776=PMID:12740394, GO:0031090=PMID:12740394, GO:0000421=GO_REF:0000039, GO:0005874=GO_REF:0000037, GO:0006914=GO_REF:0000037, GO:0031410=GO_REF:0000037, GO:0012505=GO_REF:0000039} Q9GZQ8 Microtubule-associated proteins 1A/1B light chain 3B protein 20130415 {GO:0005622=IDA, GO:0005515=IPI, GO:0005776=ISS, GO:0031090=ISS, GO:0000421=IEA, GO:0005874=IEA, GO:0006914=IEA, GO:0031410=IEA, GO:0012505=IEA} autophagy autophagic vacuole, autophagic vacuole membrane, cytoplasmic vesicle, endomembrane system, intracellular, microtubule, organelle membrane protein binding Human UniProtKB:Q9Y4P1 MAP1LC3B2 UniProtKB UniProtKB {GO:0000421=GO_REF:0000039, GO:0005874=GO_REF:0000037, GO:0006914=GO_REF:0000037, GO:0031410=GO_REF:0000037, GO:0012505=GO_REF:0000039} A6NCE7 Microtubule-associated proteins 1A/1B light chain 3 beta 2 protein 20130413 {GO:0000421=IEA, GO:0005874=IEA, GO:0006914=IEA, GO:0031410=IEA, GO:0012505=IEA} autophagy autophagic vacuole membrane, cytoplasmic vesicle, endomembrane system, microtubule Human UniProtKB-SubCell:SL-0147 MAP1LC3C IntAct UniProtKB {GO:0005515=PMID:20562859, GO:0005776=PMID:12740394, GO:0031090=PMID:12740394, GO:0000421=GO_REF:0000039, GO:0005874=GO_REF:0000037, GO:0006914=GO_REF:0000037, GO:0031410=GO_REF:0000037, GO:0012505=GO_REF:0000039} Q9BXW4 Microtubule-associated proteins 1A/1B light chain 3C protein 20130415 {GO:0005515=IPI, GO:0005776=ISS, GO:0031090=ISS, GO:0000421=IEA, GO:0005874=IEA, GO:0006914=IEA, GO:0031410=IEA, GO:0012505=IEA} autophagy autophagic vacuole, autophagic vacuole membrane, cytoplasmic vesicle, endomembrane system, microtubule, organelle membrane protein binding Human UniProtKB:Q15459 MAP1S IntAct UniProtKB {GO:0008017=PMID:15528209, GO:0005515=PMID:14627543, GO:0048471=PMID:12762840, GO:0001578=PMID:15528209, GO:0005874=PMID:15528209, GO:0048487=PMID:12762840, GO:0005819=GO_REF:0000039, GO:0006915=PMID:12762840, GO:0045202=PMID:17658481, GO:0005634=PMID:12762840, GO:0042995=PMID:17658481, GO:0003677=PMID:15907802, GO:0030425=PMID:15528209, GO:0007399=PMID:16297881, GO:0042802=GO_REF:0000019, GO:0005829=PMID:12762840, GO:0004536=PMID:15907802, GO:0051015=PMID:15528209, GO:0015631=PMID:15528209, GO:0016787=GO_REF:0000002, GO:0047497=PMID:12762840, GO:0007420=PMID:15528209, GO:0048812=PMID:15528209, GO:0043025=PMID:15528209} Q66K74 Microtubule-associated protein 1S protein 20130415 {GO:0008017=IDA, GO:0005515=IPI, GO:0048471=IDA, GO:0001578=IMP, GO:0005874=IDA, GO:0048487=IDA, GO:0005819=IEA, GO:0006915=IDA, GO:0045202=IDA, GO:0005634=IDA, GO:0042995=IDA, GO:0003677=IDA, GO:0030425=ISS, GO:0007399=ISS, GO:0042802=IEA, GO:0005829=IDA, GO:0004536=IDA, GO:0051015=IDA, GO:0015631=IDA, GO:0016787=IEA, GO:0047497=TAS, GO:0007420=ISS, GO:0048812=IEP, GO:0043025=ISS} apoptotic process, brain development, microtubule bundle formation, mitochondrion transport along microtubule, nervous system development, neuron projection morphogenesis cell projection, cytosol, dendrite, microtubule, neuronal cell body, nucleus, perinuclear region of cytoplasm, spindle, synapse DNA binding, actin filament binding, beta-tubulin binding, deoxyribonuclease activity, hydrolase activity, identical protein binding, microtubule binding, protein binding, tubulin binding Human UniProtKB:O14599 MAP2 IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0008017=GO_REF:0000002, GO:0005516=GO_REF:0000037, GO:0002162=PMID:18341635, GO:0005875=PMID:9588626, GO:0001578=GO_REF:0000019, GO:0071310=GO_REF:0000019, GO:0005874=GO_REF:0000037, GO:0021954=PMID:20846339, GO:0007409=GO_REF:0000019, GO:0031175=PMID:20846339, GO:0016358=GO_REF:0000019, GO:0048813=PMID:20846339, GO:0005737=GO_REF:0000019, GO:0005198=PMID:9588626, GO:0034399=GO_REF:0000019, GO:0043198=GO_REF:0000019, GO:0018107=GO_REF:0000019, GO:0043025=GO_REF:0000019} P11137 Microtubule-associated protein 2 protein 20130415 {GO:0005515=IPI, GO:0008017=IEA, GO:0005516=IEA, GO:0002162=IPI, GO:0005875=TAS, GO:0001578=IEA, GO:0071310=IEA, GO:0005874=IEA, GO:0021954=IEP, GO:0007409=IEA, GO:0031175=IEP, GO:0016358=IEA, GO:0048813=IEP, GO:0005737=IEA, GO:0005198=NAS, GO:0034399=IEA, GO:0043198=IEA, GO:0018107=IEA, GO:0043025=IEA} axonogenesis, cellular response to organic substance, central nervous system neuron development, dendrite development, dendrite morphogenesis, microtubule bundle formation, neuron projection development, peptidyl-threonine phosphorylation cytoplasm, dendritic shaft, microtubule, microtubule associated complex, neuronal cell body, nuclear periphery calmodulin binding, dystroglycan binding, microtubule binding, protein binding, structural molecule activity Human UniProtKB:Q13951 MAP2K1 HPA UniProtKB {GO:0005515=PMID:22752157, GO:0060711=GO_REF:0000019, GO:0060674=GO_REF:0000019, GO:0045597=GO_REF:0000019, GO:0046579=GO_REF:0000019, GO:0051403=Reactome:REACT_21308, GO:0048678=GO_REF:0000019, GO:0032402=GO_REF:0000019, GO:0002756=Reactome:REACT_6809, GO:0007173=Reactome:REACT_9417, GO:0006935=PMID:10570282, GO:0000165=Reactome:REACT_634, GO:0047496=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0002755=Reactome:REACT_27215, GO:0005938=GO_REF:0000019, GO:0017016=GO_REF:0000019, GO:0006979=GO_REF:0000019, GO:0004708=PMID:8388392, GO:0048313=GO_REF:0000019, GO:0038124=Reactome:REACT_8006, GO:0030335=GO_REF:0000019, GO:0005794=PMID:19565474, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0005816=GO_REF:0000039, GO:0051384=GO_REF:0000019, GO:0031435=GO_REF:0000019, GO:0002224=Reactome:REACT_9020, GO:0032320=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0032968=GO_REF:0000019, GO:0035666=Reactome:REACT_25281, GO:0034166=Reactome:REACT_9027, GO:0005925=PMID:19565474, GO:0034162=Reactome:REACT_9047, GO:0090398=PMID:9765203, GO:0008286=Reactome:REACT_498, GO:0048471=GO_REF:0000019, GO:0008285=PMID:9765203, GO:0034142=Reactome:REACT_6894, GO:0005886=GO_REF:0000052, GO:0071902=PMID:8388392, GO:0007264=Reactome:REACT_12077, GO:0008283=GO_REF:0000019, GO:0006928=PMID:10912793, GO:0032839=GO_REF:0000019, GO:0005634=PMID:19565474, GO:0007265=Reactome:REACT_12033, GO:0032872=PMID:19565474, GO:0051291=GO_REF:0000019, GO:0005829=Reactome:REACT_111117, GO:0005739=PMID:19565474, GO:0000187=Reactome:REACT_1482, GO:0005737=GO_REF:0000052, GO:0000186=Reactome:REACT_12005, GO:0048870=GO_REF:0000019, GO:0043204=GO_REF:0000019, GO:0007050=PMID:9765203, GO:0034138=Reactome:REACT_6783, GO:0004728=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0090170=PMID:19565474, GO:2000641=PMID:19565474, GO:0005770=PMID:19565474, GO:0034111=GO_REF:0000019, GO:0005524=GO_REF:0000019, GO:0033267=GO_REF:0000019, GO:0007165=PMID:10570282, GO:0007067=GO_REF:0000019, GO:0004672=PMID:10570282, GO:0004674=Reactome:REACT_136, GO:0030216=GO_REF:0000019, GO:0003056=GO_REF:0000019, GO:0004712=PMID:19565474, GO:0004713=GO_REF:0000037, GO:0034146=Reactome:REACT_9061, GO:0005769=PMID:19565474} Q02750 Dual specificity mitogen-activated protein kinase kinase 1 protein 20120912 {GO:0005515=IPI, GO:0060711=IEA, GO:0060674=IEA, GO:0045597=IEA, GO:0046579=IEA, GO:0051403=TAS, GO:0048678=IEA, GO:0032402=IEA, GO:0002756=TAS, GO:0007173=TAS, GO:0006935=TAS, GO:0000165=TAS, GO:0047496=IEA, GO:0007411=TAS, GO:0002755=TAS, GO:0005938=IEA, GO:0017016=IEA, GO:0006979=IEA, GO:0004708=IDA, GO:0048313=IEA, GO:0038124=TAS, GO:0030335=IEA, GO:0005794=TAS, GO:0038123=TAS, GO:0034134=TAS, GO:0005816=IEA, GO:0051384=IEA, GO:0031435=IEA, GO:0002224=TAS, GO:0032320=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:0032968=IEA, GO:0035666=TAS, GO:0034166=TAS, GO:0005925=TAS, GO:0034162=TAS, GO:0090398=IMP, GO:0008286=TAS, GO:0048471=IEA, GO:0008285=IDA, GO:0034142=TAS, GO:0005886=IDA, GO:0071902=IDA, GO:0007264=TAS, GO:0008283=IEA, GO:0006928=TAS, GO:0032839=IEA, GO:0005634=TAS, GO:0007265=TAS, GO:0032872=TAS, GO:0051291=IEA, GO:0005829=TAS, GO:0005739=TAS, GO:0000187=TAS, GO:0005737=IDA, GO:0000186=TAS, GO:0048870=IEA, GO:0043204=IEA, GO:0007050=IMP, GO:0034138=TAS, GO:0004728=IEA, GO:0048011=TAS, GO:0090170=TAS, GO:2000641=TAS, GO:0005770=TAS, GO:0034111=IEA, GO:0005524=IEA, GO:0033267=IEA, GO:0007165=TAS, GO:0007067=IEA, GO:0004672=TAS, GO:0004674=TAS, GO:0030216=IEA, GO:0003056=IEA, GO:0004712=TAS, GO:0004713=IEA, GO:0034146=TAS, GO:0005769=TAS} Golgi inheritance, MAPK cascade, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, Ras protein signal transduction, TRIF-dependent toll-like receptor signaling pathway, activation of MAPK activity, activation of MAPKK activity, axon guidance, cell cycle arrest, cell motility, cell proliferation, cellular component movement, cellular senescence, chemotaxis, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, keratinocyte differentiation, labyrinthine layer development, melanosome transport, mitosis, negative regulation of cell proliferation, negative regulation of homotypic cell-cell adhesion, neurotrophin TRK receptor signaling pathway, placenta blood vessel development, positive regulation of Ras GTPase activity, positive regulation of Ras protein signal transduction, positive regulation of cell differentiation, positive regulation of cell migration, positive regulation of protein serine/threonine kinase activity, positive regulation of transcription elongation from RNA polymerase II promoter, protein heterooligomerization, regulation of Golgi inheritance, regulation of early endosome to late endosome transport, regulation of stress-activated MAPK cascade, regulation of vascular smooth muscle contraction, response to axon injury, response to glucocorticoid stimulus, response to oxidative stress, signal transduction, small GTPase mediated signal transduction, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, vesicle transport along microtubule Golgi apparatus, axon part, cell cortex, cytoplasm, cytosol, dendrite cytoplasm, early endosome, focal adhesion, late endosome, mitochondrion, nucleus, perikaryon, perinuclear region of cytoplasm, plasma membrane, spindle pole body ATP binding, MAP kinase kinase activity, Ras GTPase binding, mitogen-activated protein kinase kinase kinase binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity, protein tyrosine kinase activity, receptor signaling protein tyrosine phosphatase activity Human MAP2K2 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0051403=Reactome:REACT_21308, GO:2000147=GO_REF:0000019, GO:0002756=Reactome:REACT_6809, GO:0007173=Reactome:REACT_9417, GO:0000165=Reactome:REACT_634, GO:0007411=Reactome:REACT_18266, GO:0002755=Reactome:REACT_27215, GO:0070371=Reactome:REACT_1183, GO:0005938=GO_REF:0000019, GO:0004708=PMID:8388392, GO:0016772=GO_REF:0000002, GO:0038124=Reactome:REACT_8006, GO:0005794=PMID:19565474, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0030165=PMID:21615688, GO:0002224=Reactome:REACT_9020, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0034166=Reactome:REACT_9027, GO:0035666=Reactome:REACT_25281, GO:0005925=PMID:19565474, GO:0034162=Reactome:REACT_9047, GO:0008286=Reactome:REACT_498, GO:0034142=Reactome:REACT_6894, GO:0071902=PMID:8388392, GO:0007264=Reactome:REACT_12077, GO:0005634=PMID:19565474, GO:0007265=Reactome:REACT_12033, GO:0032872=PMID:19565474, GO:0005829=Reactome:REACT_111117, GO:0005739=PMID:19565474, GO:0000187=Reactome:REACT_1482, GO:0000186=Reactome:REACT_12005, GO:0097110=PMID:21615688, GO:0034138=Reactome:REACT_6783, GO:0005778=PMID:21525035, GO:0048011=Reactome:REACT_11061, GO:2000641=PMID:19565474, GO:0090170=PMID:19565474, GO:0005770=PMID:19565474, GO:0036289=PMID:8388392, GO:0005576=PMID:8388392, GO:0005524=GO_REF:0000029, GO:0032947=GO_REF:0000019, GO:0004674=Reactome:REACT_2247, GO:0004712=PMID:19565474, GO:0006468=GO_REF:0000029, GO:0004713=GO_REF:0000037, GO:0034146=Reactome:REACT_9061, GO:0005769=PMID:19565474} P36507 Dual specificity mitogen-activated protein kinase kinase 2 protein 20130415 {GO:0005515=IPI, GO:0051403=TAS, GO:2000147=IEA, GO:0002756=TAS, GO:0007173=TAS, GO:0000165=TAS, GO:0007411=TAS, GO:0002755=TAS, GO:0070371=TAS, GO:0005938=IEA, GO:0004708=IDA, GO:0016772=IEA, GO:0038124=TAS, GO:0005794=TAS, GO:0038123=TAS, GO:0034134=TAS, GO:0030165=IDA, GO:0002224=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0034166=TAS, GO:0035666=TAS, GO:0005925=TAS, GO:0034162=TAS, GO:0008286=TAS, GO:0034142=TAS, GO:0071902=IDA, GO:0007264=TAS, GO:0005634=TAS, GO:0007265=TAS, GO:0032872=TAS, GO:0005829=TAS, GO:0005739=TAS, GO:0000187=TAS, GO:0000186=TAS, GO:0097110=IPI, GO:0034138=TAS, GO:0005778=IDA, GO:0048011=TAS, GO:2000641=TAS, GO:0090170=TAS, GO:0005770=TAS, GO:0036289=IDA, GO:0005576=NAS, GO:0005524=NAS, GO:0032947=IEA, GO:0004674=TAS, GO:0004712=TAS, GO:0006468=NAS, GO:0004713=IEA, GO:0034146=TAS, GO:0005769=TAS} ERK1 and ERK2 cascade, MAPK cascade, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, Ras protein signal transduction, TRIF-dependent toll-like receptor signaling pathway, activation of MAPK activity, activation of MAPKK activity, axon guidance, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, neurotrophin TRK receptor signaling pathway, peptidyl-serine autophosphorylation, positive regulation of cell motility, positive regulation of protein serine/threonine kinase activity, protein phosphorylation, regulation of Golgi inheritance, regulation of early endosome to late endosome transport, regulation of stress-activated MAPK cascade, small GTPase mediated signal transduction, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway Golgi apparatus, cell cortex, cytosol, early endosome, extracellular region, focal adhesion, late endosome, mitochondrion, nucleus, peroxisomal membrane ATP binding, MAP kinase kinase activity, PDZ domain binding, protein binding, protein complex scaffold, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity, protein tyrosine kinase activity, scaffold protein binding, transferase activity, transferring phosphorus-containing groups Human UniProtKB:P10398 MAP2K3 IntAct UniProtKB {GO:0005515=PMID:21771788, GO:0034142=Reactome:REACT_6894, GO:0051403=Reactome:REACT_21308, GO:0060048=GO_REF:0000019, GO:0005829=Reactome:REACT_21338, GO:0000187=Reactome:REACT_21399, GO:0002756=Reactome:REACT_6809, GO:0006954=GO_REF:0000019, GO:0002755=Reactome:REACT_27215, GO:0045860=PMID:11980910, GO:0034138=Reactome:REACT_6783, GO:0004708=GO_REF:0000019, GO:0016772=GO_REF:0000002, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0019901=PMID:11279118, GO:0034134=Reactome:REACT_7980, GO:0002224=Reactome:REACT_9020, GO:0005524=GO_REF:0000037, GO:0042035=GO_REF:0000019, GO:0007165=PMID:7839144, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0034166=Reactome:REACT_9027, GO:0005654=Reactome:REACT_21395, GO:0035666=Reactome:REACT_25281, GO:0004713=GO_REF:0000037, GO:0045893=PMID:11980910, GO:0034146=Reactome:REACT_9061, GO:0034162=Reactome:REACT_9047} P46734 Dual specificity mitogen-activated protein kinase kinase 3 protein 20130415 {GO:0005515=IPI, GO:0034142=TAS, GO:0051403=TAS, GO:0060048=IEA, GO:0005829=TAS, GO:0000187=TAS, GO:0002756=TAS, GO:0006954=IEA, GO:0002755=TAS, GO:0045860=IDA, GO:0034138=TAS, GO:0004708=IEA, GO:0016772=IEA, GO:0038124=TAS, GO:0038123=TAS, GO:0019901=IPI, GO:0034134=TAS, GO:0002224=TAS, GO:0005524=IEA, GO:0042035=IEA, GO:0007165=TAS, GO:0004672=IEA, GO:0004674=IEA, GO:0045087=TAS, GO:0034166=TAS, GO:0005654=TAS, GO:0035666=TAS, GO:0004713=IEA, GO:0045893=IDA, GO:0034146=TAS, GO:0034162=TAS} MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, activation of MAPK activity, cardiac muscle contraction, inflammatory response, innate immune response, positive regulation of protein kinase activity, positive regulation of transcription, DNA-dependent, regulation of cytokine biosynthetic process, signal transduction, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway cytosol, nucleoplasm ATP binding, MAP kinase kinase activity, protein binding, protein kinase activity, protein kinase binding, protein serine/threonine kinase activity, protein tyrosine kinase activity, transferase activity, transferring phosphorus-containing groups Human UniProtKB:Q99683 MAP2K4 IntAct UniProtKB {GO:0005515=PMID:9808624, GO:0034142=Reactome:REACT_6894, GO:0005634=GO_REF:0000039, GO:0051403=Reactome:REACT_21308, GO:0005829=Reactome:REACT_21367, GO:0002756=Reactome:REACT_6809, GO:0000165=GO_REF:0000019, GO:0002755=Reactome:REACT_27215, GO:0034138=Reactome:REACT_6783, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0007254=Reactome:REACT_21368, GO:0006915=GO_REF:0000037, GO:0002224=Reactome:REACT_9020, GO:0005524=GO_REF:0000037, GO:0007165=PMID:7716521, GO:0004672=PMID:7716521, GO:0004674=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0034166=Reactome:REACT_9027, GO:0035666=Reactome:REACT_25281, GO:0004713=GO_REF:0000037, GO:0071260=PMID:19593445, GO:0034146=Reactome:REACT_9061, GO:0034162=Reactome:REACT_9047} P45985 Dual specificity mitogen-activated protein kinase kinase 4 protein 20130415 {GO:0005515=IPI, GO:0034142=TAS, GO:0005634=IEA, GO:0051403=TAS, GO:0005829=TAS, GO:0002756=TAS, GO:0000165=IEA, GO:0002755=TAS, GO:0034138=TAS, GO:0038124=TAS, GO:0038123=TAS, GO:0034134=TAS, GO:0007254=TAS, GO:0006915=IEA, GO:0002224=TAS, GO:0005524=IEA, GO:0007165=TAS, GO:0004672=TAS, GO:0004674=IEA, GO:0045087=TAS, GO:0034166=TAS, GO:0035666=TAS, GO:0004713=IEA, GO:0071260=IEP, GO:0034146=TAS, GO:0034162=TAS} JNK cascade, MAPK cascade, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, apoptotic process, cellular response to mechanical stimulus, innate immune response, signal transduction, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway cytosol, nucleus ATP binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, protein tyrosine kinase activity Human UniProtKB:Q13233 MAP2K5 BHF-UCL UniProtKB {GO:0005515=PMID:17474147, GO:0030307=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=GO_REF:0000019, GO:0007507=GO_REF:0000019, GO:0000187=PMID:20551324, GO:0045944=GO_REF:0000019, GO:0034115=PMID:20551324, GO:0070375=GO_REF:0000019, GO:0090051=PMID:20551324, GO:0043154=PMID:20551324, GO:0050679=GO_REF:0000019, GO:0071499=PMID:20551324, GO:0048011=Reactome:REACT_11061, GO:0043066=PMID:20551324, GO:0045415=PMID:20551324, GO:0060761=PMID:20551324, GO:0005819=GO_REF:0000019, GO:0032088=PMID:20551324, GO:0000122=GO_REF:0000019, GO:2000342=PMID:20551324, GO:0005524=GO_REF:0000019, GO:0007165=PMID:7759517, GO:0004672=PMID:7759517, GO:0071363=PMID:20551324, GO:0004674=GO_REF:0000037, GO:0004713=GO_REF:0000037} Q13163 Dual specificity mitogen-activated protein kinase kinase 5 protein 20111121 {GO:0005515=IPI, GO:0030307=IEA, GO:0005634=IEA, GO:0046872=IEA, GO:0005829=IEA, GO:0007507=IEA, GO:0000187=ISS, GO:0045944=IEA, GO:0034115=ISS, GO:0070375=IEA, GO:0090051=ISS, GO:0043154=ISS, GO:0050679=IEA, GO:0071499=TAS, GO:0048011=TAS, GO:0043066=ISS, GO:0045415=ISS, GO:0060761=ISS, GO:0005819=IEA, GO:0032088=ISS, GO:0000122=IEA, GO:2000342=ISS, GO:0005524=IEA, GO:0007165=TAS, GO:0004672=TAS, GO:0071363=ISS, GO:0004674=IEA, GO:0004713=IEA} ERK5 cascade, activation of MAPK activity, cellular response to growth factor stimulus, cellular response to laminar fluid shear stress, heart development, negative regulation of NF-kappaB transcription factor activity, negative regulation of apoptotic process, negative regulation of cell migration involved in sprouting angiogenesis, negative regulation of chemokine (C-X-C motif) ligand 2 production, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of heterotypic cell-cell adhesion, negative regulation of interleukin-8 biosynthetic process, negative regulation of response to cytokine stimulus, negative regulation of transcription from RNA polymerase II promoter, neurotrophin TRK receptor signaling pathway, positive regulation of cell growth, positive regulation of epithelial cell proliferation, positive regulation of transcription from RNA polymerase II promoter, signal transduction cytosol, nucleus, spindle ATP binding, metal ion binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, protein tyrosine kinase activity Human UniProtKB:Q62862 MAP2K6 Reactome UniProtKB {GO:0034142=Reactome:REACT_6894, GO:0070423=Reactome:REACT_75776, GO:0051403=Reactome:REACT_21308, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_75807, GO:0042692=Reactome:REACT_21303, GO:0000187=Reactome:REACT_21399, GO:0002756=Reactome:REACT_6809, GO:0002755=Reactome:REACT_27215, GO:0007050=PMID:10848581, GO:0005856=GO_REF:0000039, GO:0034138=Reactome:REACT_6783, GO:0004708=PMID:10848581, GO:0006355=GO_REF:0000037, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0019901=PMID:11279118, GO:0034134=Reactome:REACT_7980, GO:0006915=GO_REF:0000037, GO:0002224=Reactome:REACT_9020, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0006975=PMID:10848581, GO:0007165=PMID:8621675, GO:0051149=Reactome:REACT_21402, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0005654=Reactome:REACT_21395, GO:0034166=Reactome:REACT_9027, GO:0035666=Reactome:REACT_25281, GO:0004713=GO_REF:0000037, GO:0034146=Reactome:REACT_9061, GO:0034162=Reactome:REACT_9047} P52564 Dual specificity mitogen-activated protein kinase kinase 6 protein 20130301 {GO:0034142=TAS, GO:0070423=TAS, GO:0051403=TAS, GO:0035872=TAS, GO:0005829=TAS, GO:0042692=TAS, GO:0000187=TAS, GO:0002756=TAS, GO:0002755=TAS, GO:0007050=TAS, GO:0005856=IEA, GO:0034138=TAS, GO:0004708=TAS, GO:0006355=IEA, GO:0038124=TAS, GO:0038123=TAS, GO:0019901=IPI, GO:0034134=TAS, GO:0006915=IEA, GO:0002224=TAS, GO:0005524=IEA, GO:0006351=IEA, GO:0006975=TAS, GO:0007165=TAS, GO:0051149=TAS, GO:0004672=IEA, GO:0004674=IEA, GO:0045087=TAS, GO:0005654=TAS, GO:0034166=TAS, GO:0035666=TAS, GO:0004713=IEA, GO:0034146=TAS, GO:0034162=TAS} DNA damage induced protein phosphorylation, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, activation of MAPK activity, apoptotic process, cell cycle arrest, innate immune response, muscle cell differentiation, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, nucleotide-binding oligomerization domain containing signaling pathway, positive regulation of muscle cell differentiation, regulation of transcription, DNA-dependent, signal transduction, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, transcription, DNA-dependent cytoskeleton, cytosol, nucleoplasm ATP binding, MAP kinase kinase activity, protein kinase activity, protein kinase binding, protein serine/threonine kinase activity, protein tyrosine kinase activity Human MAP2K7 BHF-UCL UniProtKB {GO:0005515=PMID:20067578, GO:0034142=Reactome:REACT_6894, GO:0005634=GO_REF:0000024, GO:0051403=Reactome:REACT_21308, GO:0005829=Reactome:REACT_21367, GO:0002756=Reactome:REACT_6809, GO:0005737=GO_REF:0000024, GO:0043525=GO_REF:0000019, GO:0002755=Reactome:REACT_27215, GO:0034138=Reactome:REACT_6783, GO:0004708=PMID:9535930, GO:0038124=Reactome:REACT_8006, GO:0000287=PMID:9535930, GO:0038123=Reactome:REACT_8005, GO:0019901=PMID:14697235, GO:0019903=GO_REF:0000024, GO:0034134=Reactome:REACT_7980, GO:0006950=PMID:9535930, GO:0007254=Reactome:REACT_21368, GO:0006915=GO_REF:0000037, GO:0031435=GO_REF:0000019, GO:0007257=GO_REF:0000024, GO:0008022=GO_REF:0000019, GO:0002224=Reactome:REACT_9020, GO:0005524=GO_REF:0000019, GO:0007165=PMID:9535930, GO:0008545=GO_REF:0000019, GO:0004674=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0035666=Reactome:REACT_25281, GO:0034166=Reactome:REACT_9027, GO:0004713=GO_REF:0000037, GO:0034146=Reactome:REACT_9061, GO:0034162=Reactome:REACT_9047} O14733 Dual specificity mitogen-activated protein kinase kinase 7 protein 20110301 {GO:0005515=IPI, GO:0034142=TAS, GO:0005634=ISS, GO:0051403=TAS, GO:0005829=TAS, GO:0002756=TAS, GO:0005737=ISS, GO:0043525=IEA, GO:0002755=TAS, GO:0034138=TAS, GO:0004708=IDA, GO:0038124=TAS, GO:0000287=IDA, GO:0038123=TAS, GO:0019901=IPI, GO:0019903=ISS, GO:0034134=TAS, GO:0006950=IDA, GO:0007254=TAS, GO:0006915=IEA, GO:0031435=IEA, GO:0007257=ISS, GO:0008022=IEA, GO:0002224=TAS, GO:0005524=IEA, GO:0007165=TAS, GO:0008545=IEA, GO:0004674=IEA, GO:0045087=TAS, GO:0035666=TAS, GO:0034166=TAS, GO:0004713=IEA, GO:0034146=TAS, GO:0034162=TAS} JNK cascade, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, activation of JUN kinase activity, apoptotic process, innate immune response, positive regulation of neuron apoptotic process, response to stress, signal transduction, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway cytoplasm, cytosol, nucleus ATP binding, JUN kinase kinase activity, MAP kinase kinase activity, magnesium ion binding, mitogen-activated protein kinase kinase kinase binding, protein C-terminus binding, protein binding, protein kinase binding, protein phosphatase binding, protein serine/threonine kinase activity, protein tyrosine kinase activity Human UniProtKB:Q8CE90 MAP3K1 GOC UniProtKB {GO:0005515=PMID:11784851, GO:0034142=Reactome:REACT_6894, GO:0005829=Reactome:REACT_24935, GO:0000186=PMID:9808624, GO:0008637=GO_REF:0000019, GO:0030838=GO_REF:0000019, GO:0002755=Reactome:REACT_27215, GO:0007179=GO_REF:0000019, GO:0043010=GO_REF:0000019, GO:0004709=PMID:9808624, GO:0030334=GO_REF:0000019, GO:0038124=Reactome:REACT_8006, GO:0019901=PMID:17906693, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0002224=Reactome:REACT_9020, GO:0005524=GO_REF:0000029, GO:0008545=GO_REF:0000019, GO:0004672=Reactome:REACT_24935, GO:0045087=Reactome:REACT_6802, GO:0042060=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0006468=PMID:9808624, GO:0034166=Reactome:REACT_9027, GO:0071260=PMID:19593445, GO:0034146=Reactome:REACT_9061, GO:0034162=Reactome:REACT_9047} Q13233 Mitogen-activated protein kinase kinase kinase 1 protein 20130413 {GO:0005515=IPI, GO:0034142=TAS, GO:0005829=TAS, GO:0000186=NAS, GO:0008637=IEA, GO:0030838=IEA, GO:0002755=TAS, GO:0007179=IEA, GO:0043010=IEA, GO:0004709=NAS, GO:0030334=IEA, GO:0038124=TAS, GO:0019901=IPI, GO:0038123=TAS, GO:0034134=TAS, GO:0002224=TAS, GO:0005524=NAS, GO:0008545=IEA, GO:0004672=TAS, GO:0045087=TAS, GO:0042060=IEA, GO:0008270=IEA, GO:0006468=NAS, GO:0034166=TAS, GO:0071260=IEP, GO:0034146=TAS, GO:0034162=TAS} MyD88-dependent toll-like receptor signaling pathway, activation of MAPKK activity, apoptotic mitochondrial changes, camera-type eye development, cellular response to mechanical stimulus, innate immune response, positive regulation of actin filament polymerization, protein phosphorylation, regulation of cell migration, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, transforming growth factor beta receptor signaling pathway, wound healing cytosol ATP binding, JUN kinase kinase activity, MAP kinase kinase kinase activity, protein binding, protein kinase activity, protein kinase binding, zinc ion binding Human MAP3K10 GOC UniProtKB {GO:0003714=GO_REF:0000024, GO:0007254=PMID:10801775, GO:0046330=PMID:17584736, GO:0043425=PMID:19801649, GO:0007256=GO_REF:0000024, GO:0006917=PMID:10801775, GO:0007257=PMID:8195146, GO:0005524=GO_REF:0000037, GO:0042803=PMID:8195146, GO:0043433=PMID:19801649, GO:0007224=PMID:18455992, GO:0004706=GO_REF:0000024, GO:0007165=PMID:10801775, GO:0005737=PMID:18455992, GO:0004672=PMID:10801775, GO:0046777=PMID:8195146, GO:0018105=PMID:19801649, GO:0004674=PMID:19801649, GO:0018107=PMID:19801649, GO:0043507=PMID:17584736, GO:0004709=GO_REF:0000002, GO:0045892=GO_REF:0000024} Q02779 Mitogen-activated protein kinase kinase kinase 10 protein 20130413 {GO:0003714=ISS, GO:0007254=TAS, GO:0046330=IMP, GO:0043425=IPI, GO:0007256=ISS, GO:0006917=TAS, GO:0007257=ISS, GO:0005524=IEA, GO:0042803=ISS, GO:0043433=IMP, GO:0007224=IMP, GO:0004706=ISS, GO:0007165=TAS, GO:0005737=IDA, GO:0004672=TAS, GO:0046777=ISS, GO:0018105=IDA, GO:0004674=IDA, GO:0018107=IDA, GO:0043507=IMP, GO:0004709=IEA, GO:0045892=ISS} JNK cascade, activation of JNKK activity, activation of JUN kinase activity, induction of apoptosis, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription, DNA-dependent, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, positive regulation of JNK cascade, positive regulation of JUN kinase activity, protein autophosphorylation, signal transduction, smoothened signaling pathway cytoplasm ATP binding, JUN kinase kinase kinase activity, MAP kinase kinase kinase activity, bHLH transcription factor binding, protein homodimerization activity, protein kinase activity, protein serine/threonine kinase activity, transcription corepressor activity Human UniProtKB:Q95UN8 MAP3K11 IntAct UniProtKB {GO:0005515=PMID:20890305, GO:0008219=GO_REF:0000019, GO:0008283=PMID:15258589, GO:0046330=PMID:17584736, GO:0042803=PMID:9829970, GO:0042802=PMID:9829970, GO:0004706=GO_REF:0000024, GO:0000187=PMID:15258589, GO:0005737=GO_REF:0000037, GO:0046777=PMID:8195146, GO:0043525=GO_REF:0000019, GO:0043507=PMID:17584736, GO:0000080=PMID:15258589, GO:0007017=PMID:12529434, GO:0004709=GO_REF:0000002, GO:0005813=PMID:12529434, GO:0005874=PMID:12529434, GO:0007254=PMID:10799501, GO:0031434=GO_REF:0000019, GO:0031435=PMID:17584736, GO:0007257=PMID:15258589, GO:0005524=GO_REF:0000019, GO:0048365=GO_REF:0000019, GO:0004672=PMID:8183572, GO:0004674=PMID:8195146, GO:0006468=PMID:11053428, GO:0004713=GO_REF:0000002} Q16584 Mitogen-activated protein kinase kinase kinase 11 protein 20130415 {GO:0005515=IPI, GO:0008219=IEA, GO:0008283=IMP, GO:0046330=IMP, GO:0042803=IPI, GO:0042802=IPI, GO:0004706=ISS, GO:0000187=IMP, GO:0005737=IEA, GO:0046777=IDA, GO:0043525=IEA, GO:0043507=IMP, GO:0000080=IMP, GO:0007017=IMP, GO:0004709=IEA, GO:0005813=IDA, GO:0005874=IDA, GO:0007254=TAS, GO:0031434=IEA, GO:0031435=IPI, GO:0007257=IMP, GO:0005524=IEA, GO:0048365=IEA, GO:0004672=TAS, GO:0004674=IDA, GO:0006468=IDA, GO:0004713=IEA} G1 phase of mitotic cell cycle, JNK cascade, activation of JUN kinase activity, activation of MAPK activity, cell death, cell proliferation, microtubule-based process, positive regulation of JNK cascade, positive regulation of JUN kinase activity, positive regulation of neuron apoptotic process, protein autophosphorylation, protein phosphorylation centrosome, cytoplasm, microtubule ATP binding, JUN kinase kinase kinase activity, MAP kinase kinase kinase activity, Rac GTPase binding, identical protein binding, mitogen-activated protein kinase kinase binding, mitogen-activated protein kinase kinase kinase binding, protein binding, protein homodimerization activity, protein kinase activity, protein serine/threonine kinase activity, protein tyrosine kinase activity Human UniProtKB:P60953 MAP3K12 IntAct UniProtKB {GO:0005515=PMID:16169070, GO:0019901=PMID:14697235, GO:0005886=GO_REF:0000024, GO:0016572=GO_REF:0000024, GO:0007254=PMID:9353328, GO:0005524=GO_REF:0000037, GO:0007243=PMID:7983011, GO:0042803=GO_REF:0000024, GO:0005829=GO_REF:0000024, GO:0030426=GO_REF:0000019, GO:0033267=GO_REF:0000019, GO:0005737=PMID:8663324, GO:0004672=PMID:8663324, GO:0046777=GO_REF:0000024, GO:0016020=PMID:9353328, GO:0018105=GO_REF:0000024, GO:0004674=GO_REF:0000024, GO:0018107=GO_REF:0000024, GO:0006468=GO_REF:0000024, GO:0004709=GO_REF:0000003} Q12852 Mitogen-activated protein kinase kinase kinase 12 protein 20130415 {GO:0005515=IPI, GO:0019901=IPI, GO:0005886=ISS, GO:0016572=ISS, GO:0007254=ISS, GO:0005524=IEA, GO:0007243=TAS, GO:0042803=ISS, GO:0005829=ISS, GO:0030426=IEA, GO:0033267=IEA, GO:0005737=TAS, GO:0004672=TAS, GO:0046777=ISS, GO:0016020=ISS, GO:0018105=ISS, GO:0004674=ISS, GO:0018107=ISS, GO:0006468=ISS, GO:0004709=IEA} JNK cascade, histone phosphorylation, intracellular protein kinase cascade, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, protein autophosphorylation, protein phosphorylation axon part, cytoplasm, cytosol, growth cone, membrane, plasma membrane ATP binding, MAP kinase kinase kinase activity, protein binding, protein homodimerization activity, protein kinase activity, protein kinase binding, protein serine/threonine kinase activity Human UniProtKB:Q70Z53 MAP3K13 IntAct UniProtKB {GO:0005515=PMID:12492477, GO:0019901=PMID:9353328, GO:0008385=PMID:12492477, GO:0007254=PMID:11726277, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0042803=PMID:11163770, GO:0042802=PMID:11163770, GO:0000186=PMID:11726277, GO:0004672=GO_REF:0000002, GO:0046777=PMID:9353328, GO:0051092=PMID:12492477, GO:0016020=PMID:9353328, GO:0004674=PMID:9353328, GO:0006468=PMID:9353328, GO:0004709=PMID:11726277} O43283 Mitogen-activated protein kinase kinase kinase 13 protein 20130415 {GO:0005515=IPI, GO:0019901=ISS, GO:0008385=IDA, GO:0007254=IDA, GO:0005524=IEA, GO:0046872=IEA, GO:0042803=IDA, GO:0042802=IPI, GO:0000186=IDA, GO:0004672=IEA, GO:0046777=IDA, GO:0051092=IDA, GO:0016020=IDA, GO:0004674=IDA, GO:0006468=IDA, GO:0004709=IDA} JNK cascade, activation of MAPKK activity, positive regulation of NF-kappaB transcription factor activity, protein autophosphorylation, protein phosphorylation IkappaB kinase complex, membrane ATP binding, MAP kinase kinase kinase activity, identical protein binding, metal ion binding, protein binding, protein homodimerization activity, protein kinase activity, protein kinase binding, protein serine/threonine kinase activity Human UniProtKB:O43283 MAP3K14 HPA UniProtKB {GO:0005515=PMID:16286467, GO:0031295=Reactome:REACT_19344, GO:0007249=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037, GO:0038061=GO_REF:0000024, GO:0043231=GO_REF:0000052, GO:0005829=Reactome:REACT_19141, GO:0005737=GO_REF:0000052, GO:0004704=GO_REF:0000024, GO:0006955=GO_REF:0000024, GO:0004672=PMID:15001576, GO:0043123=PMID:19641626, GO:0071260=PMID:19593445, GO:0004709=GO_REF:0000003} Q99558 Mitogen-activated protein kinase kinase kinase 14 protein 20111111 {GO:0005515=IPI, GO:0031295=TAS, GO:0007249=ISS, GO:0005634=IDA, GO:0005524=IEA, GO:0038061=ISS, GO:0043231=IDA, GO:0005829=TAS, GO:0005737=IDA, GO:0004704=ISS, GO:0006955=ISS, GO:0004672=IDA, GO:0043123=RCA, GO:0071260=IEP, GO:0004709=IEA} I-kappaB kinase/NF-kappaB cascade, NIK/NF-kappaB cascade, T cell costimulation, cellular response to mechanical stimulus, immune response, positive regulation of I-kappaB kinase/NF-kappaB cascade cytoplasm, cytosol, intracellular membrane-bounded organelle, nucleus ATP binding, MAP kinase kinase kinase activity, NF-kappaB-inducing kinase activity, protein binding, protein kinase activity Human MAP3K15 UniProtKB UniProtKB {GO:0004674=GO_REF:0000002, GO:0004709=GO_REF:0000003, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q6ZN16 Mitogen-activated protein kinase kinase kinase 15 protein 20130413 {GO:0004674=IEA, GO:0004709=IEA, GO:0005524=IEA, GO:0046872=IEA} ATP binding, MAP kinase kinase kinase activity, metal ion binding, protein serine/threonine kinase activity Human EC:2.7.11.25 MAP3K2 MGI UniProtKB {GO:0019901=PMID:17906693, GO:0005634=GO_REF:0000039, GO:0007257=PMID:8621389, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0000187=PMID:8621389, GO:0005737=GO_REF:0000039, GO:0004672=PMID:15001576, GO:0004674=PMID:8621389, GO:0006468=PMID:8621389, GO:0071260=PMID:19593445, GO:0045893=PMID:14515274, GO:0004709=GO_REF:0000003} Q9Y2U5 Mitogen-activated protein kinase kinase kinase 2 protein 20091109 {GO:0019901=IPI, GO:0005634=IEA, GO:0007257=TAS, GO:0005524=IEA, GO:0046872=IEA, GO:0000187=TAS, GO:0005737=IEA, GO:0004672=IDA, GO:0004674=TAS, GO:0006468=TAS, GO:0071260=IEP, GO:0045893=IDA, GO:0004709=IEA} activation of JUN kinase activity, activation of MAPK activity, cellular response to mechanical stimulus, positive regulation of transcription, DNA-dependent, protein phosphorylation cytoplasm, nucleus ATP binding, MAP kinase kinase kinase activity, metal ion binding, protein kinase activity, protein kinase binding, protein serine/threonine kinase activity Human MAP3K3 GOC UniProtKB {GO:0005515=PMID:15001576, GO:0000186=PMID:9006902, GO:0046777=PMID:15001576, GO:0004672=PMID:15001576, GO:0000165=PMID:9006902, GO:0043123=PMID:12761501, GO:0004709=GO_REF:0000003, GO:0005524=GO_REF:0000037, GO:0007243=PMID:15001576, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_22171} Q99759 Mitogen-activated protein kinase kinase kinase 3 protein 20130413 {GO:0005515=IPI, GO:0000186=TAS, GO:0046777=IDA, GO:0004672=IDA, GO:0000165=TAS, GO:0043123=IEP, GO:0004709=IEA, GO:0005524=IEA, GO:0007243=IDA, GO:0046872=IEA, GO:0005829=TAS} MAPK cascade, activation of MAPKK activity, intracellular protein kinase cascade, positive regulation of I-kappaB kinase/NF-kappaB cascade, protein autophosphorylation cytosol ATP binding, MAP kinase kinase kinase activity, metal ion binding, protein binding, protein kinase activity Human MAP3K4 PINC UniProtKB {GO:0005515=PMID:16157600, GO:0010468=GO_REF:0000019, GO:0048471=GO_REF:0000039, GO:0007254=PMID:9305639, GO:0006950=PMID:9305639, GO:0001890=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0007243=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0000186=PMID:9305639, GO:0005737=GO_REF:0000024, GO:0004672=GO_REF:0000024, GO:0004674=GO_REF:0000002, GO:0060718=GO_REF:0000019, GO:0043507=GO_REF:0000024, GO:0004709=GO_REF:0000003, GO:0019100=GO_REF:0000019} Q9Y6R4 Mitogen-activated protein kinase kinase kinase 4 protein 20030904 {GO:0005515=IPI, GO:0010468=IEA, GO:0048471=IEA, GO:0007254=TAS, GO:0006950=TAS, GO:0001890=IEA, GO:0005524=IEA, GO:0007243=ISS, GO:0046872=IEA, GO:0000186=TAS, GO:0005737=ISS, GO:0004672=ISS, GO:0004674=IEA, GO:0060718=IEA, GO:0043507=ISS, GO:0004709=IEA, GO:0019100=IEA} JNK cascade, activation of MAPKK activity, chorionic trophoblast cell differentiation, intracellular protein kinase cascade, male germ-line sex determination, placenta development, positive regulation of JUN kinase activity, regulation of gene expression, response to stress cytoplasm, perinuclear region of cytoplasm ATP binding, MAP kinase kinase kinase activity, metal ion binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human MAP3K5 GOC UniProtKB {GO:0005515=PMID:12813029, GO:0070301=PMID:20674765, GO:0043065=PMID:21771788, GO:0000287=PMID:17210579, GO:0019901=GO_REF:0000019, GO:0006919=PMID:14761963, GO:0005783=GO_REF:0000039, GO:0019903=PMID:20674765, GO:0008631=PMID:21771788, GO:0007254=PMID:21771788, GO:0007257=PMID:8974401, GO:0005524=PMID:17210579, GO:0008656=PMID:14761963, GO:0097190=PMID:8974401, GO:0042803=PMID:11920685, GO:0042802=PMID:21771788, GO:0043280=PMID:20674765, GO:0000187=GO_REF:0000019, GO:0000186=PMID:11959862, GO:0004672=PMID:21771788, GO:0000165=PMID:21771788, GO:0019048=GO_REF:0000037, GO:0045087=GO_REF:0000037, GO:0004709=PMID:17210579} Q99683 Mitogen-activated protein kinase kinase kinase 5 protein 20130413 {GO:0005515=IPI, GO:0070301=IDA, GO:0043065=IDA, GO:0000287=IDA, GO:0019901=IEA, GO:0006919=IDA, GO:0005783=IEA, GO:0019903=IPI, GO:0008631=IDA, GO:0007254=IDA, GO:0007257=TAS, GO:0005524=IDA, GO:0008656=IDA, GO:0097190=TAS, GO:0042803=IDA, GO:0042802=IPI, GO:0043280=IDA, GO:0000187=IEA, GO:0000186=IDA, GO:0004672=IDA, GO:0000165=IDA, GO:0019048=IEA, GO:0045087=IEA, GO:0004709=IDA} JNK cascade, MAPK cascade, activation of JUN kinase activity, activation of MAPK activity, activation of MAPKK activity, activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic signaling pathway, cellular response to hydrogen peroxide, innate immune response, intrinsic apoptotic signaling pathway in response to oxidative stress, positive regulation of apoptotic process, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, virus-host interaction endoplasmic reticulum ATP binding, MAP kinase kinase kinase activity, cysteine-type endopeptidase activator activity involved in apoptotic process, identical protein binding, magnesium ion binding, protein binding, protein homodimerization activity, protein kinase activity, protein kinase binding, protein phosphatase binding Human MAP3K6 GOC UniProtKB {GO:0007165=PMID:9875215, GO:0000186=PMID:9875215, GO:0000287=PMID:9875215, GO:0004674=GO_REF:0000002, GO:0006468=PMID:9875215, GO:0007257=PMID:9875215, GO:0004709=PMID:9875215, GO:0005524=PMID:9875215} O95382 Mitogen-activated protein kinase kinase kinase 6 protein 20130413 {GO:0007165=TAS, GO:0000186=IDA, GO:0000287=IDA, GO:0004674=IEA, GO:0006468=IDA, GO:0007257=TAS, GO:0004709=IDA, GO:0005524=IDA} activation of JUN kinase activity, activation of MAPKK activity, protein phosphorylation, signal transduction ATP binding, MAP kinase kinase kinase activity, magnesium ion binding, protein serine/threonine kinase activity Human MAP3K7 BHF-UCL UniProtKB {GO:0005515=PMID:21903422, GO:0046330=GO_REF:0000019, GO:0007249=Reactome:REACT_25351, GO:0051403=Reactome:REACT_21308, GO:0002756=Reactome:REACT_6809, GO:0002755=Reactome:REACT_27215, GO:0007179=GO_REF:0000019, GO:0043123=PMID:14982987, GO:0004709=PMID:11460167, GO:0004708=GO_REF:0000019, GO:0000287=GO_REF:0000002, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0002726=PMID:15125833, GO:0002224=Reactome:REACT_9020, GO:0001841=GO_REF:0000019, GO:0043966=PMID:18838386, GO:0050870=PMID:15125833, GO:0045087=Reactome:REACT_6802, GO:0034166=Reactome:REACT_9027, GO:0035666=Reactome:REACT_25281, GO:0010008=Reactome:REACT_25322, GO:0034162=Reactome:REACT_9047, GO:0050852=Reactome:REACT_12526, GO:0034142=Reactome:REACT_6894, GO:0005886=GO_REF:0000039, GO:0008385=PMID:10094049, GO:0070423=Reactome:REACT_75776, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_75887, GO:0000187=Reactome:REACT_21399, GO:0000186=PMID:9079627, GO:0051092=Reactome:REACT_21281, GO:0043507=PMID:11460167, GO:0034138=Reactome:REACT_6783, GO:0043066=GO_REF:0000019, GO:0007250=PMID:10094049, GO:0032743=PMID:15125833, GO:0007252=PMID:11460167, GO:0007254=Reactome:REACT_21368, GO:0006915=GO_REF:0000037, GO:0001525=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0004672=PMID:10094049, GO:0004674=Reactome:REACT_25375, GO:0005671=PMID:18838386, GO:0034146=Reactome:REACT_9061} O43318 Mitogen-activated protein kinase kinase kinase 7 protein 20101105 {GO:0005515=IPI, GO:0046330=IEA, GO:0007249=TAS, GO:0051403=TAS, GO:0002756=TAS, GO:0002755=TAS, GO:0007179=IEA, GO:0043123=IMP, GO:0004709=IDA, GO:0004708=IEA, GO:0000287=IEA, GO:0038124=TAS, GO:0038123=TAS, GO:0034134=TAS, GO:0002726=IMP, GO:0002224=TAS, GO:0001841=IEA, GO:0043966=IDA, GO:0050870=IC, GO:0045087=TAS, GO:0034166=TAS, GO:0035666=TAS, GO:0010008=TAS, GO:0034162=TAS, GO:0050852=TAS, GO:0034142=TAS, GO:0005886=IEA, GO:0008385=IPI, GO:0070423=TAS, GO:0035872=TAS, GO:0005829=TAS, GO:0000187=TAS, GO:0000186=IDA, GO:0051092=TAS, GO:0043507=IDA, GO:0034138=TAS, GO:0043066=IEA, GO:0007250=IMP, GO:0032743=IMP, GO:0007252=IDA, GO:0007254=TAS, GO:0006915=IEA, GO:0001525=IEA, GO:0005524=IEA, GO:0006351=IEA, GO:0004672=IDA, GO:0004674=TAS, GO:0005671=IDA, GO:0034146=TAS} I-kappaB kinase/NF-kappaB cascade, I-kappaB phosphorylation, JNK cascade, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, T cell receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, activation of MAPK activity, activation of MAPKK activity, activation of NF-kappaB-inducing kinase activity, angiogenesis, apoptotic process, histone H3 acetylation, innate immune response, negative regulation of apoptotic process, neural tube formation, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, nucleotide-binding oligomerization domain containing signaling pathway, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of JNK cascade, positive regulation of JUN kinase activity, positive regulation of NF-kappaB transcription factor activity, positive regulation of T cell activation, positive regulation of T cell cytokine production, positive regulation of interleukin-2 production, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway Ada2/Gcn5/Ada3 transcription activator complex, IkappaB kinase complex, cytosol, endosome membrane, plasma membrane ATP binding, MAP kinase kinase activity, MAP kinase kinase kinase activity, magnesium ion binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human MAP3K8 HPA UniProtKB {GO:0005515=PMID:22939624, GO:0005737=GO_REF:0000052, GO:0007049=GO_REF:0000002, GO:0000287=GO_REF:0000002, GO:0004672=GO_REF:0000002, GO:0004674=PMID:8226782, GO:0031295=Reactome:REACT_19344, GO:0006468=PMID:2072910, GO:0004709=GO_REF:0000003, GO:0005524=GO_REF:0000002, GO:0005829=Reactome:REACT_22206} Q5T857 Mitogen-activated protein kinase kinase kinase 8 protein 20090616 {GO:0005515=IPI, GO:0005737=IDA, GO:0007049=IEA, GO:0000287=IEA, GO:0004672=IEA, GO:0004674=TAS, GO:0031295=TAS, GO:0006468=TAS, GO:0004709=IEA, GO:0005524=IEA, GO:0005829=TAS} T cell costimulation, cell cycle, protein phosphorylation cytoplasm, cytosol ATP binding, MAP kinase kinase kinase activity, magnesium ion binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human MAP3K9 GOC UniProtKB {GO:0005515=PMID:22939624, GO:0006355=GO_REF:0000037, GO:0006915=GO_REF:0000037, GO:0007256=GO_REF:0000024, GO:0007257=PMID:8195146, GO:0005575=GO_REF:0000015, GO:0005524=GO_REF:0000029, GO:0006351=GO_REF:0000037, GO:0042803=PMID:8195146, GO:0004706=GO_REF:0000024, GO:0046777=PMID:15610029, GO:0004674=PMID:15610029, GO:0006468=GO_REF:0000029, GO:0004713=GO_REF:0000002, GO:0004709=GO_REF:0000002, GO:0004708=PMID:8477742} P80192 Mitogen-activated protein kinase kinase kinase 9 protein 20130413 {GO:0005515=IPI, GO:0006355=IEA, GO:0006915=IEA, GO:0007256=ISS, GO:0007257=ISS, GO:0005575=ND, GO:0005524=NAS, GO:0006351=IEA, GO:0042803=ISS, GO:0004706=ISS, GO:0046777=IDA, GO:0004674=IDA, GO:0006468=NAS, GO:0004713=IEA, GO:0004709=IEA, GO:0004708=NAS} activation of JNKK activity, activation of JUN kinase activity, apoptotic process, protein autophosphorylation, protein phosphorylation, regulation of transcription, DNA-dependent, transcription, DNA-dependent cellular_component ATP binding, JUN kinase kinase kinase activity, MAP kinase kinase activity, MAP kinase kinase kinase activity, protein binding, protein homodimerization activity, protein serine/threonine kinase activity, protein tyrosine kinase activity Human UniProtKB:Q95UN8 MAP4 HPA UniProtKB {GO:0008017=GO_REF:0000019, GO:0005515=PMID:17474147, GO:0072686=PMID:21822276, GO:0005886=GO_REF:0000052, GO:0005875=PMID:1905296, GO:0005874=GO_REF:0000037, GO:0051294=PMID:21822276, GO:0005737=GO_REF:0000052, GO:0005198=PMID:1905296, GO:0051012=PMID:21822276, GO:0015630=GO_REF:0000052, GO:0007052=PMID:21822276, GO:0051301=PMID:21822276} P27816 Microtubule-associated protein 4 protein 20111111 {GO:0008017=IEA, GO:0005515=IPI, GO:0072686=IDA, GO:0005886=IDA, GO:0005875=TAS, GO:0005874=IEA, GO:0051294=IMP, GO:0005737=IDA, GO:0005198=TAS, GO:0051012=IMP, GO:0015630=IDA, GO:0007052=IMP, GO:0051301=IMP} cell division, establishment of spindle orientation, microtubule sliding, mitotic spindle organization cytoplasm, microtubule, microtubule associated complex, microtubule cytoskeleton, mitotic spindle, plasma membrane microtubule binding, protein binding, structural molecule activity Human MAP4K1 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0008349=PMID:11053428, GO:0006950=PMID:8824585, GO:0007257=PMID:8824585, GO:0005524=PMID:8824585, GO:0007243=PMID:8824585, GO:0005083=GO_REF:0000002, GO:0004672=PMID:8824585, GO:0000185=PMID:11053428, GO:0018105=PMID:11053428, GO:0016301=GO_REF:0000038, GO:0004674=PMID:8824585, GO:0006468=PMID:8824585} Q92918 Mitogen-activated protein kinase kinase kinase kinase 1 protein 20130415 {GO:0005515=IPI, GO:0008349=IDA, GO:0006950=IDA, GO:0007257=TAS, GO:0005524=IDA, GO:0007243=IDA, GO:0005083=IEA, GO:0004672=TAS, GO:0000185=IC, GO:0018105=IDA, GO:0016301=IEA, GO:0004674=IDA, GO:0006468=IDA} activation of JUN kinase activity, activation of MAPKKK activity, intracellular protein kinase cascade, peptidyl-serine phosphorylation, protein phosphorylation, response to stress ATP binding, MAP kinase kinase kinase kinase activity, kinase activity, protein binding, protein kinase activity, protein serine/threonine kinase activity, small GTPase regulator activity Human UniProtKB:P62993 MAP4K2 UniProtKB UniProtKB {GO:0005515=PMID:11784851, GO:0007254=PMID:7477268, GO:0006950=PMID:8643544, GO:0046330=PMID:17584736, GO:0031435=PMID:17584736, GO:0007257=PMID:17584736, GO:0005524=GO_REF:0000038, GO:0007243=PMID:11784851, GO:0006903=GO_REF:0000029, GO:0016323=GO_REF:0000039, GO:0006955=PMID:7515885, GO:0005083=GO_REF:0000002, GO:0004672=GO_REF:0000002, GO:0000139=GO_REF:0000039, GO:0004674=GO_REF:0000038, GO:0045087=GO_REF:0000037, GO:0006468=PMID:11784851} Q86VU3 Mitogen-activated protein kinase kinase kinase kinase protein 20130413 {GO:0005515=IPI, GO:0007254=TAS, GO:0006950=TAS, GO:0046330=IDA, GO:0031435=IPI, GO:0007257=IDA, GO:0005524=IEA, GO:0007243=IDA, GO:0006903=NAS, GO:0016323=IEA, GO:0006955=TAS, GO:0005083=IEA, GO:0004672=IEA, GO:0000139=IEA, GO:0004674=IEA, GO:0045087=IEA, GO:0006468=IDA} JNK cascade, activation of JUN kinase activity, immune response, innate immune response, intracellular protein kinase cascade, positive regulation of JNK cascade, protein phosphorylation, response to stress, vesicle targeting Golgi membrane, basolateral plasma membrane ATP binding, mitogen-activated protein kinase kinase kinase binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, small GTPase regulator activity Human UniProtKB-KW:KW-0067 MAP4K3 IntAct UniProtKB {GO:0005515=PMID:21983831, GO:0005083=GO_REF:0000002, GO:0004672=PMID:9275185, GO:0004674=PMID:9275185, GO:0016301=GO_REF:0000038, GO:0007254=PMID:9275185, GO:0006950=PMID:9275185, GO:0006468=PMID:9275185, GO:0005524=PMID:9275185, GO:0007243=PMID:9275185, GO:0016772=GO_REF:0000002} Q8IVH8 Mitogen-activated protein kinase kinase kinase kinase 3 protein 20130415 {GO:0005515=IPI, GO:0005083=IEA, GO:0004672=TAS, GO:0004674=IDA, GO:0016301=IEA, GO:0007254=TAS, GO:0006950=IDA, GO:0006468=IDA, GO:0005524=IDA, GO:0007243=IDA, GO:0016772=IEA} JNK cascade, intracellular protein kinase cascade, protein phosphorylation, response to stress ATP binding, kinase activity, protein binding, protein kinase activity, protein serine/threonine kinase activity, small GTPase regulator activity, transferase activity, transferring phosphorus-containing groups Human UniProtKB:Q13094 MAP4K4 UniProtKB UniProtKB {GO:0046328=PMID:14966141, GO:0005515=PMID:14966141, GO:0005737=PMID:14966141, GO:0005083=GO_REF:0000002, GO:0004672=GO_REF:0000002, GO:0004674=PMID:9890973, GO:0006950=PMID:9890973, GO:0006468=PMID:9890973, GO:0005524=PMID:9890973, GO:0007243=PMID:9890973, GO:0016772=GO_REF:0000002} O95819 Mitogen-activated protein kinase kinase kinase kinase 4 protein 20100910 {GO:0046328=IDA, GO:0005515=IPI, GO:0005737=IDA, GO:0005083=IEA, GO:0004672=IEA, GO:0004674=IDA, GO:0006950=IDA, GO:0006468=IDA, GO:0005524=IDA, GO:0007243=IDA, GO:0016772=IEA} intracellular protein kinase cascade, protein phosphorylation, regulation of JNK cascade, response to stress cytoplasm ATP binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, small GTPase regulator activity, transferase activity, transferring phosphorus-containing groups Human MAP4K5 HPA UniProtKB {GO:0005515=PMID:21706016, GO:0005737=GO_REF:0000052, GO:0005083=GO_REF:0000002, GO:0004672=PMID:9038372, GO:0005886=GO_REF:0000052, GO:0004674=PMID:9038372, GO:0006950=PMID:9038372, GO:0006468=PMID:9038372, GO:0007257=PMID:9038372, GO:0005524=PMID:9038372, GO:0007243=PMID:9038372} Q9Y4K4 Mitogen-activated protein kinase kinase kinase kinase 5 protein 20110516 {GO:0005515=IPI, GO:0005737=IDA, GO:0005083=IEA, GO:0004672=TAS, GO:0005886=IDA, GO:0004674=IDA, GO:0006950=IDA, GO:0006468=IDA, GO:0007257=TAS, GO:0005524=IDA, GO:0007243=IDA} activation of JUN kinase activity, intracellular protein kinase cascade, protein phosphorylation, response to stress cytoplasm, plasma membrane ATP binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, small GTPase regulator activity Human MAP6 UniProtKB UniProtKB {GO:0008017=GO_REF:0000019, GO:0005516=GO_REF:0000037, GO:0048471=PMID:17210638, GO:0005794=GO_REF:0000039, GO:0005874=PMID:17210638, GO:0007026=GO_REF:0000002} Q96JE9 Microtubule-associated protein 6 protein 20110317 {GO:0008017=IEA, GO:0005516=IEA, GO:0048471=IDA, GO:0005794=IEA, GO:0005874=IDA, GO:0007026=IEA} negative regulation of microtubule depolymerization Golgi apparatus, microtubule, perinuclear region of cytoplasm calmodulin binding, microtubule binding Human MAP7 HPA UniProtKB {GO:0048471=GO_REF:0000039, GO:0005886=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:0001578=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0007281=GO_REF:0000019, GO:0048872=GO_REF:0000019, GO:0016323=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0060009=GO_REF:0000019, GO:0035265=GO_REF:0000019, GO:0015630=GO_REF:0000052, GO:0032526=GO_REF:0000019, GO:0006997=GO_REF:0000019, GO:0006687=GO_REF:0000019, GO:0005875=PMID:8408219, GO:0005874=GO_REF:0000037, GO:0005102=GO_REF:0000024, GO:0000226=PMID:8408219, GO:0006970=GO_REF:0000024, GO:0072659=GO_REF:0000024, GO:0009566=GO_REF:0000019, GO:0000902=GO_REF:0000019, GO:0007163=PMID:8408219, GO:0005198=PMID:8408219, GO:0033327=GO_REF:0000019} Q14244 Ensconsin protein 20111111 {GO:0048471=IEA, GO:0005886=IEA, GO:0008283=IEA, GO:0001578=IEA, GO:0007283=IEA, GO:0007281=IEA, GO:0048872=IEA, GO:0016323=IEA, GO:0005737=IDA, GO:0060009=IEA, GO:0035265=IEA, GO:0015630=IDA, GO:0032526=IEA, GO:0006997=IEA, GO:0006687=IEA, GO:0005875=TAS, GO:0005874=IEA, GO:0005102=ISS, GO:0000226=TAS, GO:0006970=ISS, GO:0072659=ISS, GO:0009566=IEA, GO:0000902=IEA, GO:0007163=TAS, GO:0005198=TAS, GO:0033327=IEA} Leydig cell differentiation, Sertoli cell development, cell morphogenesis, cell proliferation, establishment or maintenance of cell polarity, fertilization, germ cell development, glycosphingolipid metabolic process, homeostasis of number of cells, microtubule bundle formation, microtubule cytoskeleton organization, nucleus organization, organ growth, protein localization to plasma membrane, response to osmotic stress, response to retinoic acid, spermatogenesis basolateral plasma membrane, cytoplasm, microtubule, microtubule associated complex, microtubule cytoskeleton, perinuclear region of cytoplasm, plasma membrane receptor binding, structural molecule activity Human MAP7D1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0005819=GO_REF:0000039} Q3KQU3 MAP7 domain-containing protein 1 protein 20130413 {GO:0005737=IEA, GO:0005819=IEA} cytoplasm, spindle Human UniProtKB-SubCell:SL-0251 MAP7D2 null null {} null null null null {} null null null MAP7D3 HPA UniProtKB {GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005819=GO_REF:0000039, GO:0005634=GO_REF:0000052} Q8IWC1 MAP7 domain-containing protein 3 protein 20110516 {GO:0005813=IDA, GO:0005737=IDA, GO:0005730=IDA, GO:0005819=IEA, GO:0005634=IDA} centrosome, cytoplasm, nucleolus, nucleus, spindle Human MAP9 HPA UniProtKB {GO:0000910=GO_REF:0000002, GO:0007067=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0007088=GO_REF:0000002, GO:0005794=GO_REF:0000052, GO:0005874=GO_REF:0000037, GO:0005819=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0051225=GO_REF:0000002} Q49MG5 Microtubule-associated protein 9 protein 20110516 {GO:0000910=IEA, GO:0007067=IEA, GO:0005737=IDA, GO:0007088=IEA, GO:0005794=IDA, GO:0005874=IEA, GO:0005819=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0051225=IEA} cytokinesis, mitosis, regulation of mitosis, spindle assembly Golgi apparatus, cytoplasm, microtubule, nucleolus, nucleus, spindle Human MAPK1 HPA UniProtKB {GO:0005515=PMID:16286470, GO:0043627=GO_REF:0000019, GO:0072584=PMID:19565474, GO:0019858=GO_REF:0000019, GO:0051403=Reactome:REACT_21308, GO:0002756=Reactome:REACT_6809, GO:0018105=PMID:15850461, GO:0007173=Reactome:REACT_9417, GO:0006935=PMID:10706854, GO:0007411=Reactome:REACT_18266, GO:0000165=Reactome:REACT_634, GO:0002755=Reactome:REACT_27215, GO:0060716=GO_REF:0000019, GO:0009887=GO_REF:0000019, GO:0070371=Reactome:REACT_1183, GO:0005856=PMID:19565474, GO:0031663=GO_REF:0000019, GO:0004707=GO_REF:0000003, GO:0038127=PMID:15133037, GO:0038124=Reactome:REACT_8006, GO:0030335=GO_REF:0000019, GO:0005794=PMID:19565474, GO:0038123=Reactome:REACT_8005, GO:0005815=GO_REF:0000039, GO:0019902=PMID:19494114, GO:0034134=Reactome:REACT_7980, GO:0006950=PMID:10958679, GO:0005819=GO_REF:0000039, GO:0030168=Reactome:REACT_798, GO:0009636=GO_REF:0000019, GO:0031435=GO_REF:0000019, GO:0002224=Reactome:REACT_9020, GO:0070849=PMID:18794356, GO:0033598=GO_REF:0000019, GO:0007049=GO_REF:0000037, GO:0051493=PMID:19565474, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0035666=Reactome:REACT_25281, GO:0034166=Reactome:REACT_9027, GO:0005654=Reactome:REACT_21251, GO:0001784=GO_REF:0000019, GO:0045596=GO_REF:0000019, GO:0045893=GO_REF:0000019, GO:0038096=Reactome:REACT_160123, GO:0005925=PMID:19565474, GO:0034162=Reactome:REACT_9047, GO:0008134=GO_REF:0000019, GO:0008286=Reactome:REACT_498, GO:0050853=GO_REF:0000019, GO:0050852=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0034142=Reactome:REACT_6894, GO:0007264=Reactome:REACT_12077, GO:0007268=Reactome:REACT_13685, GO:0032839=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0007265=Reactome:REACT_12033, GO:0060397=Reactome:REACT_111133, GO:0032872=PMID:19565474, GO:0031143=GO_REF:0000019, GO:0005829=Reactome:REACT_160224, GO:0005739=PMID:19565474, GO:0051090=Reactome:REACT_21326, GO:0000187=Reactome:REACT_1482, GO:0000186=Reactome:REACT_12005, GO:0005737=PMID:18794356, GO:0015630=GO_REF:0000052, GO:0043204=GO_REF:0000019, GO:0034138=Reactome:REACT_6783, GO:0048011=Reactome:REACT_11061, GO:0090170=PMID:19565474, GO:2000641=PMID:19565474, GO:0005770=PMID:19565474, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0045727=GO_REF:0000019, GO:0006917=PMID:10958679, GO:0000189=GO_REF:0000019, GO:0005524=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0008353=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0006974=GO_REF:0000019, GO:0019233=GO_REF:0000019, GO:0033267=GO_REF:0000019, GO:0007165=PMID:1540184, GO:0007596=Reactome:REACT_604, GO:0004674=PMID:18794356, GO:0005901=PMID:19565474, GO:0019048=GO_REF:0000037, GO:0034146=Reactome:REACT_9061, GO:0043330=GO_REF:0000019, GO:0005769=PMID:19565474} P28482 Mitogen-activated protein kinase 1 protein 20080205 {GO:0005515=IPI, GO:0043627=IEA, GO:0072584=TAS, GO:0019858=IEA, GO:0051403=TAS, GO:0002756=TAS, GO:0018105=IDA, GO:0007173=TAS, GO:0006935=TAS, GO:0007411=TAS, GO:0000165=TAS, GO:0002755=TAS, GO:0060716=IEA, GO:0009887=IEA, GO:0070371=TAS, GO:0005856=TAS, GO:0031663=IEA, GO:0004707=IEA, GO:0038127=IDA, GO:0038124=TAS, GO:0030335=IEA, GO:0005794=TAS, GO:0038123=TAS, GO:0005815=IEA, GO:0019902=IPI, GO:0034134=TAS, GO:0006950=TAS, GO:0005819=IEA, GO:0030168=TAS, GO:0009636=IEA, GO:0031435=IEA, GO:0002224=TAS, GO:0070849=IDA, GO:0033598=IEA, GO:0007049=IEA, GO:0051493=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0035666=TAS, GO:0034166=TAS, GO:0005654=TAS, GO:0001784=IEA, GO:0045596=IEA, GO:0045893=IEA, GO:0038096=TAS, GO:0005925=TAS, GO:0034162=TAS, GO:0008134=IEA, GO:0008286=TAS, GO:0050853=IEA, GO:0050852=IEA, GO:0008284=IEA, GO:0034142=TAS, GO:0007264=TAS, GO:0007268=TAS, GO:0032839=IEA, GO:0005634=IDA, GO:0007265=TAS, GO:0060397=TAS, GO:0032872=TAS, GO:0031143=IEA, GO:0005829=TAS, GO:0005739=TAS, GO:0051090=TAS, GO:0000187=TAS, GO:0000186=TAS, GO:0005737=IDA, GO:0015630=IDA, GO:0043204=IEA, GO:0034138=TAS, GO:0048011=TAS, GO:0090170=TAS, GO:2000641=TAS, GO:0005770=TAS, GO:0005730=IDA, GO:0006915=IEA, GO:0045727=IEA, GO:0006917=TAS, GO:0000189=IEA, GO:0005524=IEA, GO:0003677=IEA, GO:0008353=ISS, GO:0006351=IEA, GO:0006974=IEA, GO:0019233=IEA, GO:0033267=IEA, GO:0007165=TAS, GO:0007596=TAS, GO:0004674=IDA, GO:0005901=TAS, GO:0019048=IEA, GO:0034146=TAS, GO:0043330=IEA, GO:0005769=TAS} B cell receptor signaling pathway, ERBB signaling pathway, ERK1 and ERK2 cascade, Fc-gamma receptor signaling pathway involved in phagocytosis, JAK-STAT cascade involved in growth hormone signaling pathway, MAPK cascade, MAPK import into nucleus, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, Ras protein signal transduction, T cell receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, activation of MAPK activity, activation of MAPKK activity, apoptotic process, axon guidance, blood coagulation, caveolin-mediated endocytosis, cell cycle, chemotaxis, cytosine metabolic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, induction of apoptosis, innate immune response, insulin receptor signaling pathway, labyrinthine layer blood vessel development, lipopolysaccharide-mediated signaling pathway, mammary gland epithelial cell proliferation, negative regulation of cell differentiation, neurotrophin TRK receptor signaling pathway, organ morphogenesis, peptidyl-serine phosphorylation, platelet activation, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of transcription, DNA-dependent, positive regulation of translation, regulation of Golgi inheritance, regulation of cytoskeleton organization, regulation of early endosome to late endosome transport, regulation of sequence-specific DNA binding transcription factor activity, regulation of stress-activated MAPK cascade, response to DNA damage stimulus, response to epidermal growth factor stimulus, response to estrogen stimulus, response to exogenous dsRNA, response to stress, response to toxic substance, sensory perception of pain, signal transduction, small GTPase mediated signal transduction, stress-activated MAPK cascade, synaptic transmission, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, transcription, DNA-dependent, virus-host interaction Golgi apparatus, axon part, caveola, cytoplasm, cytoskeleton, cytosol, dendrite cytoplasm, early endosome, focal adhesion, late endosome, microtubule cytoskeleton, microtubule organizing center, mitochondrion, nucleolus, nucleoplasm, nucleus, perikaryon, pseudopodium, spindle ATP binding, DNA binding, MAP kinase activity, RNA polymerase II carboxy-terminal domain kinase activity, mitogen-activated protein kinase kinase kinase binding, phosphatase binding, phosphotyrosine binding, protein binding, protein serine/threonine kinase activity, transcription factor binding Human MAPK10 InterPro UniProtKB {GO:0005515=PMID:21988832, GO:0034142=Reactome:REACT_6894, GO:0005886=GO_REF:0000024, GO:0051403=Reactome:REACT_21308, GO:0005829=Reactome:REACT_21385, GO:0005739=GO_REF:0000024, GO:0000187=PMID:7826642, GO:0051090=Reactome:REACT_21326, GO:0004705=PMID:8654373, GO:0002756=Reactome:REACT_6809, GO:0005737=GO_REF:0000024, GO:0002755=Reactome:REACT_27215, GO:0034138=Reactome:REACT_6783, GO:0004708=PMID:7826642, GO:0016772=GO_REF:0000002, GO:0004707=GO_REF:0000002, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0007254=Reactome:REACT_21368, GO:0007258=PMID:8654373, GO:0002224=Reactome:REACT_9020, GO:0005524=GO_REF:0000002, GO:0007165=PMID:8654373, GO:0004672=GO_REF:0000002, GO:0045087=Reactome:REACT_6802, GO:0034166=Reactome:REACT_9027, GO:0035666=Reactome:REACT_25281, GO:0005654=Reactome:REACT_21385, GO:0034146=Reactome:REACT_9061, GO:0034162=Reactome:REACT_9047} Q499Y8 Mitogen-activated protein kinase 10 protein 20130413 {GO:0005515=IPI, GO:0034142=TAS, GO:0005886=ISS, GO:0051403=TAS, GO:0005829=TAS, GO:0005739=ISS, GO:0000187=TAS, GO:0051090=TAS, GO:0004705=ISS, GO:0002756=TAS, GO:0005737=ISS, GO:0002755=TAS, GO:0034138=TAS, GO:0004708=TAS, GO:0016772=IEA, GO:0004707=IEA, GO:0038124=TAS, GO:0038123=TAS, GO:0034134=TAS, GO:0007254=TAS, GO:0007258=TAS, GO:0002224=TAS, GO:0005524=IEA, GO:0007165=TAS, GO:0004672=IEA, GO:0045087=TAS, GO:0034166=TAS, GO:0035666=TAS, GO:0005654=TAS, GO:0034146=TAS, GO:0034162=TAS} JNK cascade, JUN phosphorylation, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, activation of MAPK activity, innate immune response, regulation of sequence-specific DNA binding transcription factor activity, signal transduction, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway cytoplasm, cytosol, mitochondrion, nucleoplasm, plasma membrane ATP binding, JUN kinase activity, MAP kinase activity, MAP kinase kinase activity, protein binding, protein kinase activity, transferase activity, transferring phosphorus-containing groups Human InterPro:IPR000719|InterPro:IPR008351 MAPK11 IntAct UniProtKB {GO:0005515=PMID:17254968, GO:0010467=Reactome:REACT_71, GO:0034142=Reactome:REACT_6894, GO:0007265=Reactome:REACT_12033, GO:0051403=Reactome:REACT_21308, GO:0007243=PMID:8663524, GO:0005829=Reactome:REACT_25129, GO:0042692=Reactome:REACT_21303, GO:0051090=Reactome:REACT_21326, GO:0000187=Reactome:REACT_21399, GO:0002756=Reactome:REACT_6809, GO:0002755=Reactome:REACT_27215, GO:0034138=Reactome:REACT_6783, GO:0004707=PMID:10330143, GO:0048011=Reactome:REACT_11061, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0034134=Reactome:REACT_7980, GO:0006950=PMID:8663524, GO:0002224=Reactome:REACT_9020, GO:0005524=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0007165=PMID:8663524, GO:0051149=Reactome:REACT_21402, GO:0004672=GO_REF:0000002, GO:0004674=Reactome:REACT_21375, GO:0045087=Reactome:REACT_6802, GO:0034166=Reactome:REACT_9027, GO:0035666=Reactome:REACT_25281, GO:0005654=Reactome:REACT_21395, GO:0034146=Reactome:REACT_9061, GO:0034162=Reactome:REACT_9047} Q15759 Mitogen-activated protein kinase 11 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0034142=TAS, GO:0007265=TAS, GO:0051403=TAS, GO:0007243=IDA, GO:0005829=TAS, GO:0042692=TAS, GO:0051090=TAS, GO:0000187=TAS, GO:0002756=TAS, GO:0002755=TAS, GO:0034138=TAS, GO:0004707=IDA, GO:0048011=TAS, GO:0038124=TAS, GO:0038123=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0034134=TAS, GO:0006950=IDA, GO:0002224=TAS, GO:0005524=IEA, GO:0006351=IEA, GO:0007165=TAS, GO:0051149=TAS, GO:0004672=IEA, GO:0004674=TAS, GO:0045087=TAS, GO:0034166=TAS, GO:0035666=TAS, GO:0005654=TAS, GO:0034146=TAS, GO:0034162=TAS} MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, RNA metabolic process, Ras protein signal transduction, TRIF-dependent toll-like receptor signaling pathway, activation of MAPK activity, gene expression, innate immune response, intracellular protein kinase cascade, mRNA metabolic process, muscle cell differentiation, neurotrophin TRK receptor signaling pathway, positive regulation of muscle cell differentiation, regulation of sequence-specific DNA binding transcription factor activity, response to stress, signal transduction, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, transcription, DNA-dependent cytosol, nucleoplasm ATP binding, MAP kinase activity, protein binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB:P04637 MAPK12 BHF-UCL UniProtKB {GO:0005515=PMID:12761180, GO:0048011=Reactome:REACT_11061, GO:0006355=GO_REF:0000037, GO:0000287=PMID:10508788, GO:0007265=Reactome:REACT_12033, GO:0005524=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0005829=Reactome:REACT_25129, GO:0006975=PMID:10848581, GO:0042692=Reactome:REACT_21303, GO:0005739=GO_REF:0000039, GO:0007165=PMID:8633070, GO:0051149=Reactome:REACT_21402, GO:0007517=PMID:8633070, GO:0004672=GO_REF:0000002, GO:0018105=PMID:15850461, GO:0004674=PMID:8633070, GO:0007050=PMID:10848581, GO:0005654=Reactome:REACT_21288, GO:0045445=PMID:8633070, GO:0004707=GO_REF:0000003} P53778 Mitogen-activated protein kinase 12 protein 20120123 {GO:0005515=IPI, GO:0048011=TAS, GO:0006355=IEA, GO:0000287=IDA, GO:0007265=TAS, GO:0005524=IEA, GO:0006351=IEA, GO:0005829=TAS, GO:0006975=TAS, GO:0042692=TAS, GO:0005739=IEA, GO:0007165=TAS, GO:0051149=TAS, GO:0007517=TAS, GO:0004672=IEA, GO:0018105=IDA, GO:0004674=IDA, GO:0007050=TAS, GO:0005654=TAS, GO:0045445=IDA, GO:0004707=IEA} DNA damage induced protein phosphorylation, Ras protein signal transduction, cell cycle arrest, muscle cell differentiation, muscle organ development, myoblast differentiation, neurotrophin TRK receptor signaling pathway, peptidyl-serine phosphorylation, positive regulation of muscle cell differentiation, regulation of transcription, DNA-dependent, signal transduction, transcription, DNA-dependent cytosol, mitochondrion, nucleoplasm ATP binding, MAP kinase activity, magnesium ion binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human MAPK13 UniProtKB UniProtKB {GO:0032755=PMID:19279008, GO:0005515=PMID:22447027, GO:0006355=GO_REF:0000037, GO:0048011=Reactome:REACT_11061, GO:0006950=PMID:9218798, GO:0006970=PMID:9731215, GO:0007265=Reactome:REACT_12033, GO:0005524=GO_REF:0000038, GO:0006351=GO_REF:0000037, GO:0007243=PMID:9218798, GO:0005829=Reactome:REACT_25129, GO:0007049=GO_REF:0000037, GO:0004672=GO_REF:0000002, GO:0018105=PMID:15850461, GO:0000165=PMID:9731215, GO:0004674=PMID:12244047, GO:0050729=PMID:19279008, GO:0004707=GO_REF:0000002} Q5U4A5 MAPK13 protein protein 20130413 {GO:0032755=IMP, GO:0005515=IPI, GO:0006355=IEA, GO:0048011=TAS, GO:0006950=IDA, GO:0006970=IDA, GO:0007265=TAS, GO:0005524=IEA, GO:0006351=IEA, GO:0007243=IDA, GO:0005829=TAS, GO:0007049=IEA, GO:0004672=IEA, GO:0018105=IDA, GO:0000165=IDA, GO:0004674=IDA, GO:0050729=IC, GO:0004707=IEA} MAPK cascade, Ras protein signal transduction, cell cycle, intracellular protein kinase cascade, neurotrophin TRK receptor signaling pathway, peptidyl-serine phosphorylation, positive regulation of inflammatory response, positive regulation of interleukin-6 production, regulation of transcription, DNA-dependent, response to osmotic stress, response to stress, transcription, DNA-dependent cytosol ATP binding, MAP kinase activity, protein binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB-KW:KW-0067 MAPK14 BHF-UCL UniProtKB {GO:0005515=PMID:19776015, GO:0010467=Reactome:REACT_71, GO:0051403=Reactome:REACT_21308, GO:0007243=PMID:10838079, GO:0042692=Reactome:REACT_21303, GO:0002756=Reactome:REACT_6809, GO:0018105=GO_REF:0000024, GO:0006935=PMID:10706854, GO:0002062=GO_REF:0000019, GO:0002755=Reactome:REACT_27215, GO:0031663=GO_REF:0000019, GO:0004708=PMID:10706854, GO:0004707=PMID:20932473, GO:0019395=GO_REF:0000019, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0034134=Reactome:REACT_7980, GO:0006950=PMID:7997261, GO:0030168=Reactome:REACT_798, GO:0002224=Reactome:REACT_9020, GO:0071479=PMID:20160708, GO:0042770=PMID:20160708, GO:0043536=PMID:18440775, GO:0000922=GO_REF:0000019, GO:0051149=Reactome:REACT_21402, GO:0045648=GO_REF:0000019, GO:0007519=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0042307=GO_REF:0000019, GO:0035666=Reactome:REACT_25281, GO:0034166=Reactome:REACT_9027, GO:0005654=Reactome:REACT_21395, GO:0000077=GO_REF:0000019, GO:2000379=PMID:20160708, GO:0034162=Reactome:REACT_9047, GO:0051146=GO_REF:0000019, GO:0034142=Reactome:REACT_6894, GO:0051525=GO_REF:0000024, GO:0006928=PMID:10912793, GO:0005634=GO_REF:0000024, GO:0007265=Reactome:REACT_12033, GO:0090400=PMID:20160708, GO:0005829=Reactome:REACT_25129, GO:0005739=GO_REF:0000019, GO:0051090=Reactome:REACT_21326, GO:0000187=Reactome:REACT_21399, GO:0005737=GO_REF:0000024, GO:0045944=GO_REF:0000019, GO:0006006=GO_REF:0000019, GO:0034138=Reactome:REACT_6783, GO:0048011=Reactome:REACT_11061, GO:0030316=GO_REF:0000024, GO:0006915=GO_REF:0000037, GO:0001525=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0000902=GO_REF:0000019, GO:0007165=PMID:10706854, GO:0004672=GO_REF:0000002, GO:0004674=Reactome:REACT_21375, GO:0007596=Reactome:REACT_604, GO:0032495=GO_REF:0000019, GO:0034146=Reactome:REACT_9061, GO:0070935=PMID:20932473, GO:0007166=PMID:10706854} Q16539 Mitogen-activated protein kinase 14 protein 20121128 {GO:0005515=IPI, GO:0010467=TAS, GO:0051403=TAS, GO:0007243=IDA, GO:0042692=TAS, GO:0002756=TAS, GO:0018105=ISS, GO:0006935=TAS, GO:0002062=IEA, GO:0002755=TAS, GO:0031663=IEA, GO:0004708=TAS, GO:0004707=IDA, GO:0019395=IEA, GO:0038124=TAS, GO:0038123=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0034134=TAS, GO:0006950=IDA, GO:0030168=TAS, GO:0002224=TAS, GO:0071479=IMP, GO:0042770=IMP, GO:0043536=IMP, GO:0000922=IEA, GO:0051149=TAS, GO:0045648=IEA, GO:0007519=IEA, GO:0045087=TAS, GO:0042307=IEA, GO:0035666=TAS, GO:0034166=TAS, GO:0005654=TAS, GO:0000077=IEA, GO:2000379=IMP, GO:0034162=TAS, GO:0051146=IEA, GO:0034142=TAS, GO:0051525=ISS, GO:0006928=TAS, GO:0005634=ISS, GO:0007265=TAS, GO:0090400=IMP, GO:0005829=TAS, GO:0005739=IEA, GO:0051090=TAS, GO:0000187=TAS, GO:0005737=ISS, GO:0045944=IEA, GO:0006006=IEA, GO:0034138=TAS, GO:0048011=TAS, GO:0030316=ISS, GO:0006915=IEA, GO:0001525=IEA, GO:0005524=IEA, GO:0006351=IEA, GO:0000902=IEA, GO:0007165=TAS, GO:0004672=IEA, GO:0004674=TAS, GO:0007596=TAS, GO:0032495=IEA, GO:0034146=TAS, GO:0070935=TAS, GO:0007166=TAS} 3'-UTR-mediated mRNA stabilization, DNA damage checkpoint, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, RNA metabolic process, Ras protein signal transduction, TRIF-dependent toll-like receptor signaling pathway, activation of MAPK activity, angiogenesis, apoptotic process, blood coagulation, cell morphogenesis, cell surface receptor signaling pathway, cellular component movement, cellular response to ionizing radiation, chemotaxis, chondrocyte differentiation, fatty acid oxidation, gene expression, glucose metabolic process, innate immune response, intracellular protein kinase cascade, lipopolysaccharide-mediated signaling pathway, mRNA metabolic process, muscle cell differentiation, neurotrophin TRK receptor signaling pathway, osteoclast differentiation, peptidyl-serine phosphorylation, platelet activation, positive regulation of blood vessel endothelial cell migration, positive regulation of erythrocyte differentiation, positive regulation of muscle cell differentiation, positive regulation of protein import into nucleus, positive regulation of reactive oxygen species metabolic process, positive regulation of transcription from RNA polymerase II promoter, regulation of sequence-specific DNA binding transcription factor activity, response to muramyl dipeptide, response to stress, signal transduction, signal transduction in response to DNA damage, skeletal muscle tissue development, stress-activated MAPK cascade, stress-induced premature senescence, striated muscle cell differentiation, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, transcription, DNA-dependent cytoplasm, cytosol, mitochondrion, nucleoplasm, nucleus, spindle pole ATP binding, MAP kinase activity, MAP kinase kinase activity, NFAT protein binding, protein binding, protein kinase activity, protein serine/threonine kinase activity NOT Human MAPK15 GOC UniProtKB {GO:0045732=GO_REF:0000019, GO:0017124=PMID:11875070, GO:0005634=GO_REF:0000019, GO:0005576=PMID:11875070, GO:0000122=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0005622=PMID:11875070, GO:0046777=PMID:11875070, GO:0000165=PMID:11875070, GO:0001934=GO_REF:0000019, GO:0031398=GO_REF:0000019, GO:0008156=GO_REF:0000019, GO:0032355=GO_REF:0000019, GO:0004707=PMID:11875070} Q8TD08 Mitogen-activated protein kinase 15 protein 20130413 {GO:0045732=IEA, GO:0017124=NAS, GO:0005634=IEA, GO:0005576=NAS, GO:0000122=IEA, GO:0005524=IEA, GO:0005622=NAS, GO:0046777=IDA, GO:0000165=IDA, GO:0001934=IEA, GO:0031398=IEA, GO:0008156=IEA, GO:0032355=IEA, GO:0004707=IDA} MAPK cascade, negative regulation of DNA replication, negative regulation of transcription from RNA polymerase II promoter, positive regulation of protein catabolic process, positive regulation of protein phosphorylation, positive regulation of protein ubiquitination, protein autophosphorylation, response to estradiol stimulus extracellular region, intracellular, nucleus ATP binding, MAP kinase activity, SH3 domain binding Human MAPK1IP1L null null {} null null null null {} null null null MAPK3 HPA UniProtKB {GO:0005515=PMID:19776015, GO:0010467=Reactome:REACT_71, GO:0051216=GO_REF:0000019, GO:0019221=Reactome:REACT_25229, GO:0072584=PMID:19565474, GO:0006361=Reactome:REACT_2232, GO:0006360=Reactome:REACT_1309, GO:0051403=Reactome:REACT_21308, GO:2000657=GO_REF:0000019, GO:0002756=Reactome:REACT_6809, GO:0007173=Reactome:REACT_9417, GO:0007411=Reactome:REACT_18266, GO:0000165=PMID:20018936, GO:0002755=Reactome:REACT_27215, GO:0009887=GO_REF:0000019, GO:0070374=PMID:19664780, GO:0005856=PMID:19565474, GO:0031663=GO_REF:0000019, GO:0038083=PMID:8388392, GO:0004707=Reactome:REACT_180, GO:0038124=Reactome:REACT_8006, GO:0005794=PMID:19565474, GO:0038123=Reactome:REACT_8005, GO:0019902=PMID:19494114, GO:0034134=Reactome:REACT_7980, GO:0030168=Reactome:REACT_798, GO:0030509=PMID:19664780, GO:0002224=Reactome:REACT_9020, GO:0070849=PMID:18794356, GO:0007049=GO_REF:0000037, GO:0051493=PMID:19565474, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0035666=Reactome:REACT_25281, GO:0034166=Reactome:REACT_9027, GO:0001784=GO_REF:0000019, GO:0005654=Reactome:REACT_21251, GO:0038096=Reactome:REACT_160123, GO:0005925=PMID:19565474, GO:0034162=Reactome:REACT_9047, GO:0008286=Reactome:REACT_498, GO:0034142=Reactome:REACT_6894, GO:0007264=Reactome:REACT_12077, GO:0007265=Reactome:REACT_12033, GO:0005634=GO_REF:0000052, GO:0060397=Reactome:REACT_111133, GO:0032872=PMID:19565474, GO:0035066=PMID:20018936, GO:0031143=GO_REF:0000019, GO:0005829=Reactome:REACT_160224, GO:0005739=PMID:19565474, GO:0051090=Reactome:REACT_21326, GO:0000187=Reactome:REACT_1482, GO:0005737=GO_REF:0000019, GO:0000186=Reactome:REACT_12005, GO:0045944=PMID:20018936, GO:0015630=GO_REF:0000052, GO:0034138=Reactome:REACT_6783, GO:0070498=PMID:20018936, GO:0048011=Reactome:REACT_11061, GO:0090170=PMID:19565474, GO:2000641=PMID:19565474, GO:0005770=PMID:19565474, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0005524=GO_REF:0000029, GO:0006351=GO_REF:0000019, GO:0006974=GO_REF:0000019, GO:0019233=GO_REF:0000019, GO:0033129=PMID:20018936, GO:0007596=Reactome:REACT_604, GO:0019048=GO_REF:0000037, GO:0005901=PMID:19565474, GO:0001934=PMID:19664780, GO:0006468=PMID:7687743, GO:0034146=Reactome:REACT_9061, GO:0071260=PMID:19593445, GO:0043330=GO_REF:0000019, GO:0005769=PMID:19565474} P27361 Mitogen-activated protein kinase 3 protein 20080205 {GO:0005515=IPI, GO:0010467=TAS, GO:0051216=IEA, GO:0019221=TAS, GO:0072584=TAS, GO:0006361=TAS, GO:0006360=TAS, GO:0051403=TAS, GO:2000657=IEA, GO:0002756=TAS, GO:0007173=TAS, GO:0007411=TAS, GO:0000165=NAS, GO:0002755=TAS, GO:0009887=IEA, GO:0070374=IMP, GO:0005856=TAS, GO:0031663=IEA, GO:0038083=IDA, GO:0004707=TAS, GO:0038124=TAS, GO:0005794=TAS, GO:0038123=TAS, GO:0019902=IPI, GO:0034134=TAS, GO:0030168=TAS, GO:0030509=IMP, GO:0002224=TAS, GO:0070849=IDA, GO:0007049=IEA, GO:0051493=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0035666=TAS, GO:0034166=TAS, GO:0001784=IEA, GO:0005654=TAS, GO:0038096=TAS, GO:0005925=TAS, GO:0034162=TAS, GO:0008286=TAS, GO:0034142=TAS, GO:0007264=TAS, GO:0007265=TAS, GO:0005634=IDA, GO:0060397=TAS, GO:0032872=TAS, GO:0035066=IMP, GO:0031143=IEA, GO:0005829=TAS, GO:0005739=TAS, GO:0051090=TAS, GO:0000187=TAS, GO:0005737=IEA, GO:0000186=TAS, GO:0045944=IMP, GO:0015630=IDA, GO:0034138=TAS, GO:0070498=IMP, GO:0048011=TAS, GO:0090170=TAS, GO:2000641=TAS, GO:0005770=TAS, GO:0005730=IDA, GO:0006915=IEA, GO:0005524=NAS, GO:0006351=IEA, GO:0006974=IEA, GO:0019233=IEA, GO:0033129=IMP, GO:0007596=TAS, GO:0019048=IEA, GO:0005901=TAS, GO:0001934=IMP, GO:0006468=IDA, GO:0034146=TAS, GO:0071260=IEP, GO:0043330=IEA, GO:0005769=TAS} BMP signaling pathway, Fc-gamma receptor signaling pathway involved in phagocytosis, JAK-STAT cascade involved in growth hormone signaling pathway, MAPK cascade, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, Ras protein signal transduction, TRIF-dependent toll-like receptor signaling pathway, activation of MAPK activity, activation of MAPKK activity, apoptotic process, axon guidance, blood coagulation, cartilage development, caveolin-mediated endocytosis, cell cycle, cellular response to mechanical stimulus, cytokine-mediated signaling pathway, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, gene expression, innate immune response, insulin receptor signaling pathway, interleukin-1-mediated signaling pathway, lipopolysaccharide-mediated signaling pathway, negative regulation of apolipoprotein binding, neurotrophin TRK receptor signaling pathway, organ morphogenesis, peptidyl-tyrosine autophosphorylation, platelet activation, positive regulation of ERK1 and ERK2 cascade, positive regulation of histone acetylation, positive regulation of histone phosphorylation, positive regulation of protein phosphorylation, positive regulation of transcription from RNA polymerase II promoter, protein phosphorylation, regulation of Golgi inheritance, regulation of cytoskeleton organization, regulation of early endosome to late endosome transport, regulation of sequence-specific DNA binding transcription factor activity, regulation of stress-activated MAPK cascade, response to DNA damage stimulus, response to epidermal growth factor stimulus, response to exogenous dsRNA, sensory perception of pain, small GTPase mediated signal transduction, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, transcription from RNA polymerase I promoter, transcription initiation from RNA polymerase I promoter, transcription, DNA-dependent, virus-host interaction Golgi apparatus, caveola, cytoplasm, cytoskeleton, cytosol, early endosome, focal adhesion, late endosome, microtubule cytoskeleton, mitochondrion, nucleolus, nucleoplasm, nucleus, pseudopodium ATP binding, MAP kinase activity, phosphatase binding, phosphotyrosine binding, protein binding Human MAPK4 GOC UniProtKB {GO:0005515=PMID:22939624, GO:0007049=GO_REF:0000037, GO:0005737=GO_REF:0000024, GO:0046982=GO_REF:0000019, GO:0019901=GO_REF:0000024, GO:0000165=PMID:7969157, GO:0006468=PMID:7969157, GO:0005634=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0042803=GO_REF:0000024, GO:0004707=GO_REF:0000003} P31152 Mitogen-activated protein kinase 4 protein 20130413 {GO:0005515=IPI, GO:0007049=IEA, GO:0005737=ISS, GO:0046982=IEA, GO:0019901=ISS, GO:0000165=TAS, GO:0006468=TAS, GO:0005634=ISS, GO:0005524=IEA, GO:0042803=ISS, GO:0004707=IEA} MAPK cascade, cell cycle, protein phosphorylation cytoplasm, nucleus ATP binding, MAP kinase activity, protein binding, protein heterodimerization activity, protein homodimerization activity, protein kinase binding Human MAPK6 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0007165=PMID:2032290, GO:0005737=GO_REF:0000024, GO:0007049=GO_REF:0000037, GO:0046982=GO_REF:0000019, GO:0019901=GO_REF:0000019, GO:0004674=PMID:2032290, GO:0005634=GO_REF:0000024, GO:0006468=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0004707=GO_REF:0000024} Q16659 Mitogen-activated protein kinase 6 protein 20130415 {GO:0005515=IPI, GO:0007165=TAS, GO:0005737=ISS, GO:0007049=IEA, GO:0046982=IEA, GO:0019901=IEA, GO:0004674=TAS, GO:0005634=ISS, GO:0006468=ISS, GO:0005524=IEA, GO:0004707=ISS} cell cycle, protein phosphorylation, signal transduction cytoplasm, nucleus ATP binding, MAP kinase activity, protein binding, protein heterodimerization activity, protein kinase binding, protein serine/threonine kinase activity Human UniProtKB:P12504 MAPK7 BHF-UCL UniProtKB {GO:0005515=PMID:7759517, GO:0070301=PMID:23043106, GO:0034142=Reactome:REACT_6894, GO:0071560=PMID:18588859, GO:0005634=PMID:23043106, GO:0051403=Reactome:REACT_21308, GO:0030154=GO_REF:0000037, GO:0005829=PMID:23043106, GO:0002756=Reactome:REACT_6809, GO:0005737=PMID:22869143, GO:0018105=GO_REF:0000019, GO:0002755=Reactome:REACT_27215, GO:0060548=PMID:23043106, GO:0034115=PMID:20551324, GO:0034138=Reactome:REACT_6783, GO:0036003=PMID:23043106, GO:0051019=PMID:23043106, GO:0016772=GO_REF:0000002, GO:0004707=GO_REF:0000003, GO:0071499=PMID:23043106, GO:0043066=PMID:23043106, GO:0048011=Reactome:REACT_11061, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0051534=GO_REF:0000019, GO:0034134=Reactome:REACT_7980, GO:0045765=GO_REF:0000019, GO:0006915=GO_REF:0000019, GO:0002224=Reactome:REACT_9020, GO:0005524=GO_REF:0000037, GO:0007165=PMID:7646528, GO:0007049=GO_REF:0000037, GO:0071363=PMID:20551324, GO:0004674=GO_REF:0000019, GO:0050728=PMID:20551324, GO:0045087=Reactome:REACT_6802, GO:0016605=PMID:22869143, GO:0034166=Reactome:REACT_9027, GO:0005654=Reactome:REACT_12539, GO:0035666=Reactome:REACT_25281, GO:0034146=Reactome:REACT_9061, GO:0034162=Reactome:REACT_9047} Q13164 Mitogen-activated protein kinase 7 protein 20121203 {GO:0005515=IPI, GO:0070301=IMP, GO:0034142=TAS, GO:0071560=IDA, GO:0005634=IDA, GO:0051403=TAS, GO:0030154=IEA, GO:0005829=IDA, GO:0002756=TAS, GO:0005737=IDA, GO:0018105=IEA, GO:0002755=TAS, GO:0060548=IMP, GO:0034115=IGI, GO:0034138=TAS, GO:0036003=IMP, GO:0051019=IPI, GO:0016772=IEA, GO:0004707=IEA, GO:0071499=IMP, GO:0043066=IC, GO:0048011=TAS, GO:0038124=TAS, GO:0038123=TAS, GO:0051534=IEA, GO:0034134=TAS, GO:0045765=IEA, GO:0006915=IEA, GO:0002224=TAS, GO:0005524=IEA, GO:0007165=TAS, GO:0007049=IEA, GO:0071363=IGI, GO:0004674=IEA, GO:0050728=TAS, GO:0045087=TAS, GO:0016605=IDA, GO:0034166=TAS, GO:0005654=TAS, GO:0035666=TAS, GO:0034146=TAS, GO:0034162=TAS} MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, apoptotic process, cell cycle, cell differentiation, cellular response to growth factor stimulus, cellular response to hydrogen peroxide, cellular response to laminar fluid shear stress, cellular response to transforming growth factor beta stimulus, innate immune response, negative regulation of NFAT protein import into nucleus, negative regulation of apoptotic process, negative regulation of cell death, negative regulation of heterotypic cell-cell adhesion, negative regulation of inflammatory response, neurotrophin TRK receptor signaling pathway, peptidyl-serine phosphorylation, positive regulation of transcription from RNA polymerase II promoter in response to stress, regulation of angiogenesis, signal transduction, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway PML body, cytoplasm, cytosol, nucleoplasm, nucleus ATP binding, MAP kinase activity, mitogen-activated protein kinase binding, protein binding, protein serine/threonine kinase activity, transferase activity, transferring phosphorus-containing groups Human MAPK8 UniProtKB UniProtKB {GO:0005515=PMID:16533805, GO:0010468=GO_REF:0000019, GO:0051403=Reactome:REACT_21308, GO:0002756=Reactome:REACT_6809, GO:0004705=PMID:21095239, GO:1900740=Reactome:REACT_2100, GO:0018105=PMID:20027304, GO:0002755=Reactome:REACT_27215, GO:0018107=PMID:20027304, GO:0009411=PMID:14967141, GO:0004707=GO_REF:0000002, GO:0035033=PMID:20027304, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0006950=PMID:8137421, GO:0002224=Reactome:REACT_9020, GO:0001503=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0005654=Reactome:REACT_21385, GO:0034166=Reactome:REACT_9027, GO:0035666=Reactome:REACT_25281, GO:0046686=GO_REF:0000019, GO:0034162=Reactome:REACT_9047, GO:0032091=PMID:21095239, GO:0034142=Reactome:REACT_6894, GO:0042826=PMID:20027304, GO:2001235=GO_REF:0000019, GO:0005634=PMID:20027304, GO:0005829=Reactome:REACT_25384, GO:0005739=GO_REF:0000019, GO:0032880=PMID:20027304, GO:0051090=Reactome:REACT_21326, GO:0034138=Reactome:REACT_6783, GO:0043066=PMID:14967141, GO:0048011=Reactome:REACT_13776, GO:2000017=GO_REF:0000019, GO:0007254=Reactome:REACT_21368, GO:0006915=Reactome:REACT_13643, GO:0007258=PMID:14967141, GO:0005524=GO_REF:0000038, GO:0097190=Reactome:REACT_13720, GO:0097193=Reactome:REACT_964, GO:0010628=PMID:22065586, GO:0004674=PMID:14967141, GO:0090045=PMID:20027304, GO:0031063=PMID:20027304, GO:0071260=PMID:19593445, GO:0034146=Reactome:REACT_9061} Q308M2 Mitogen-activated protein kinase 8 protein 20130413 {GO:0005515=IPI, GO:0010468=IEA, GO:0051403=TAS, GO:0002756=TAS, GO:0004705=IDA, GO:1900740=TAS, GO:0018105=IDA, GO:0002755=TAS, GO:0018107=IMP, GO:0009411=IDA, GO:0004707=IEA, GO:0035033=IMP, GO:0038124=TAS, GO:0038123=TAS, GO:0034134=TAS, GO:0006950=TAS, GO:0002224=TAS, GO:0001503=IEA, GO:0045087=TAS, GO:0005654=TAS, GO:0034166=TAS, GO:0035666=TAS, GO:0046686=IEA, GO:0034162=TAS, GO:0032091=IDA, GO:0034142=TAS, GO:0042826=IPI, GO:2001235=IEA, GO:0005634=IDA, GO:0005829=TAS, GO:0005739=IEA, GO:0032880=IDA, GO:0051090=TAS, GO:0034138=TAS, GO:0043066=IDA, GO:0048011=TAS, GO:2000017=IEA, GO:0007254=TAS, GO:0006915=TAS, GO:0007258=IDA, GO:0005524=IEA, GO:0097190=TAS, GO:0097193=TAS, GO:0010628=IMP, GO:0004674=IDA, GO:0090045=IMP, GO:0031063=IMP, GO:0071260=IEP, GO:0034146=TAS} JNK cascade, JUN phosphorylation, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, apoptotic process, apoptotic signaling pathway, cellular response to mechanical stimulus, innate immune response, intrinsic apoptotic signaling pathway, negative regulation of apoptotic process, negative regulation of protein binding, neurotrophin TRK receptor signaling pathway, ossification, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, positive regulation of apoptotic signaling pathway, positive regulation of deacetylase activity, positive regulation of determination of dorsal identity, positive regulation of gene expression, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, regulation of gene expression, regulation of histone deacetylation, regulation of protein localization, regulation of sequence-specific DNA binding transcription factor activity, response to UV, response to cadmium ion, response to stress, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway cytosol, mitochondrion, nucleoplasm, nucleus ATP binding, JUN kinase activity, MAP kinase activity, histone deacetylase binding, histone deacetylase regulator activity, protein binding, protein serine/threonine kinase activity Human UniProtKB-KW:KW-0067 MAPK8IP1 IntAct UniProtKB {GO:0005515=PMID:18286207, GO:0048471=GO_REF:0000039, GO:0045202=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0005829=GO_REF:0000019, GO:0046328=GO_REF:0000024, GO:0005737=PMID:10574993, GO:0046329=GO_REF:0000019, GO:0043508=GO_REF:0000019, GO:0008432=GO_REF:0000019, GO:0016192=GO_REF:0000024, GO:0043066=GO_REF:0000019, GO:0006355=GO_REF:0000019, GO:0031966=GO_REF:0000039, GO:0019901=PMID:11238452, GO:0044302=GO_REF:0000019, GO:0031434=GO_REF:0000019, GO:0031435=GO_REF:0000019, GO:0044294=GO_REF:0000019, GO:0044295=GO_REF:0000019, GO:0007258=GO_REF:0000019, GO:0044297=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0004860=PMID:9933567, GO:0019894=PMID:11238452, GO:0005078=PMID:11238452} Q9UQF2 C-Jun-amino-terminal kinase-interacting protein 1 protein 20130415 {GO:0005515=IPI, GO:0048471=IEA, GO:0045202=IEA, GO:0005634=IEA, GO:0005829=IEA, GO:0046328=ISS, GO:0005737=IDA, GO:0046329=IEA, GO:0043508=IEA, GO:0008432=IEA, GO:0016192=ISS, GO:0043066=IEA, GO:0006355=IEA, GO:0031966=IEA, GO:0019901=IPI, GO:0044302=IEA, GO:0031434=IEA, GO:0031435=IEA, GO:0044294=IEA, GO:0044295=IEA, GO:0007258=IEA, GO:0044297=IEA, GO:0005789=IEA, GO:0004860=TAS, GO:0019894=IPI, GO:0005078=IPI} JUN phosphorylation, negative regulation of JNK cascade, negative regulation of JUN kinase activity, negative regulation of apoptotic process, regulation of JNK cascade, regulation of transcription, DNA-dependent, vesicle-mediated transport axonal growth cone, cell body, cytoplasm, cytosol, dendritic growth cone, dentate gyrus mossy fiber, endoplasmic reticulum membrane, mitochondrial membrane, nucleus, perinuclear region of cytoplasm, synapse JUN kinase binding, MAP-kinase scaffold activity, kinesin binding, mitogen-activated protein kinase kinase binding, mitogen-activated protein kinase kinase kinase binding, protein binding, protein kinase binding, protein kinase inhibitor activity Human UniProtKB:O43318 MAPK8IP2 BHF-UCL UniProtKB {GO:0051966=GO_REF:0000024, GO:0010469=GO_REF:0000024, GO:0019901=PMID:10490659, GO:0007617=GO_REF:0000019, GO:0007254=GO_REF:0000019, GO:0060079=GO_REF:0000024, GO:2000311=GO_REF:0000024, GO:0014069=GO_REF:0000024, GO:2000310=GO_REF:0000024, GO:0046328=PMID:10490659, GO:0048813=GO_REF:0000024, GO:0005737=PMID:10490659, GO:0007172=PMID:10490659, GO:0001540=PMID:12023290, GO:0005198=PMID:10490659, GO:0035176=GO_REF:0000024, GO:0043025=GO_REF:0000019, GO:0001662=GO_REF:0000024, GO:0019894=GO_REF:0000024, GO:0005078=PMID:10490659, GO:0046958=GO_REF:0000024} Q13387 C-Jun-amino-terminal kinase-interacting protein 2 protein 20110117 {GO:0051966=ISS, GO:0010469=ISS, GO:0019901=IPI, GO:0007617=IEA, GO:0007254=IEA, GO:0060079=ISS, GO:2000311=ISS, GO:0014069=ISS, GO:2000310=ISS, GO:0046328=IDA, GO:0048813=ISS, GO:0005737=IDA, GO:0007172=TAS, GO:0001540=NAS, GO:0005198=TAS, GO:0035176=ISS, GO:0043025=IEA, GO:0001662=ISS, GO:0019894=ISS, GO:0005078=NAS, GO:0046958=ISS} JNK cascade, behavioral fear response, dendrite morphogenesis, mating behavior, nonassociative learning, regulation of JNK cascade, regulation of N-methyl-D-aspartate selective glutamate receptor activity, regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity, regulation of excitatory postsynaptic membrane potential, regulation of receptor activity, regulation of synaptic transmission, glutamatergic, signal complex assembly, social behavior cytoplasm, neuronal cell body, postsynaptic density MAP-kinase scaffold activity, beta-amyloid binding, kinesin binding, protein kinase binding, structural molecule activity Human UniProtKB:Q9ERE9 MAPK8IP3 UniProtKB UniProtKB {GO:0010468=GO_REF:0000019, GO:0019901=GO_REF:0000024, GO:0048286=GO_REF:0000019, GO:0007585=GO_REF:0000019, GO:0060425=GO_REF:0000019, GO:0031434=GO_REF:0000019, GO:0031435=GO_REF:0000019, GO:0007257=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0005790=GO_REF:0000019, GO:0046328=GO_REF:0000024, GO:0008104=GO_REF:0000019, GO:0000139=GO_REF:0000024, GO:0007411=GO_REF:0000019, GO:0019894=GO_REF:0000024, GO:0030673=GO_REF:0000019, GO:0030900=GO_REF:0000019, GO:0016192=GO_REF:0000024, GO:0008432=GO_REF:0000019, GO:0005078=GO_REF:0000024} Q9UPT6 C-Jun-amino-terminal kinase-interacting protein 3 protein 20041006 {GO:0010468=IEA, GO:0019901=ISS, GO:0048286=IEA, GO:0007585=IEA, GO:0060425=IEA, GO:0031434=IEA, GO:0031435=IEA, GO:0007257=IEA, GO:0009791=IEA, GO:0001701=IEA, GO:0030425=IEA, GO:0005790=IEA, GO:0046328=ISS, GO:0008104=IEA, GO:0000139=ISS, GO:0007411=IEA, GO:0019894=ISS, GO:0030673=IEA, GO:0030900=IEA, GO:0016192=ISS, GO:0008432=IEA, GO:0005078=ISS} activation of JUN kinase activity, axon guidance, forebrain development, in utero embryonic development, lung alveolus development, lung morphogenesis, post-embryonic development, protein localization, regulation of JNK cascade, regulation of gene expression, respiratory gaseous exchange, vesicle-mediated transport Golgi membrane, axolemma, dendrite, smooth endoplasmic reticulum JUN kinase binding, MAP-kinase scaffold activity, kinesin binding, mitogen-activated protein kinase kinase binding, mitogen-activated protein kinase kinase kinase binding, protein kinase binding Human UniProtKB:Q9ESN9 MAPK9 BHF-UCL UniProtKB {GO:0005515=PMID:19776015, GO:0014075=GO_REF:0000019, GO:0051403=Reactome:REACT_21308, GO:0010770=GO_REF:0000019, GO:0031175=GO_REF:0000019, GO:0046328=GO_REF:0000019, GO:0004705=PMID:8654373, GO:0002756=Reactome:REACT_6809, GO:0034644=GO_REF:0000019, GO:0016301=GO_REF:0000038, GO:0002755=Reactome:REACT_27215, GO:0071356=GO_REF:0000019, GO:0031396=GO_REF:0000019, GO:0004707=GO_REF:0000002, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0010744=PMID:18262097, GO:0034134=Reactome:REACT_7980, GO:0031394=GO_REF:0000019, GO:0006950=PMID:7969172, GO:0009636=GO_REF:0000019, GO:0031435=GO_REF:0000019, GO:0032722=GO_REF:0000019, GO:0007417=GO_REF:0000019, GO:0002224=Reactome:REACT_9020, GO:0008656=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0071347=GO_REF:0000019, GO:0035666=Reactome:REACT_25281, GO:0034166=Reactome:REACT_9027, GO:0005654=Reactome:REACT_21385, GO:0045893=GO_REF:0000019, GO:0046686=GO_REF:0000019, GO:0034162=Reactome:REACT_9047, GO:0008134=PMID:10376527, GO:0034142=Reactome:REACT_6894, GO:0006626=GO_REF:0000019, GO:2001235=GO_REF:0000019, GO:0001836=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0045429=GO_REF:0000019, GO:0005829=Reactome:REACT_21385, GO:0005739=GO_REF:0000019, GO:0051090=Reactome:REACT_21326, GO:0034138=Reactome:REACT_6783, GO:0043065=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0007254=Reactome:REACT_21368, GO:0005524=GO_REF:0000019, GO:0009612=GO_REF:0000019, GO:0010628=PMID:18262097, GO:0044445=GO_REF:0000019, GO:0071222=GO_REF:0000019, GO:0071363=GO_REF:0000019, GO:0001934=GO_REF:0000019, GO:0032308=GO_REF:0000019, GO:0051770=GO_REF:0000019, GO:0034146=Reactome:REACT_9061} P45984 Mitogen-activated protein kinase 9 protein 20090115 {GO:0005515=IPI, GO:0014075=IEA, GO:0051403=TAS, GO:0010770=IEA, GO:0031175=IEA, GO:0046328=IEA, GO:0004705=IDA, GO:0002756=TAS, GO:0034644=IEA, GO:0016301=IEA, GO:0002755=TAS, GO:0071356=IEA, GO:0031396=IEA, GO:0004707=IEA, GO:0038124=TAS, GO:0038123=TAS, GO:0010744=IMP, GO:0034134=TAS, GO:0031394=IEA, GO:0006950=TAS, GO:0009636=IEA, GO:0031435=IEA, GO:0032722=IEA, GO:0007417=IEA, GO:0002224=TAS, GO:0008656=IEA, GO:0045087=TAS, GO:0071347=IEA, GO:0035666=TAS, GO:0034166=TAS, GO:0005654=TAS, GO:0045893=IEA, GO:0046686=IEA, GO:0034162=TAS, GO:0008134=IDA, GO:0034142=TAS, GO:0006626=IEA, GO:2001235=IEA, GO:0001836=IEA, GO:0005634=IEA, GO:0045429=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0051090=TAS, GO:0034138=TAS, GO:0043065=IEA, GO:0042493=IEA, GO:0007254=TAS, GO:0005524=IEA, GO:0009612=IEA, GO:0010628=IMP, GO:0044445=IEA, GO:0071222=IEA, GO:0071363=IEA, GO:0001934=IEA, GO:0032308=IEA, GO:0051770=IEA, GO:0034146=TAS} JNK cascade, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, cellular response to UV, cellular response to growth factor stimulus, cellular response to interleukin-1, cellular response to lipopolysaccharide, cellular response to tumor necrosis factor, central nervous system development, innate immune response, neuron projection development, positive regulation of apoptotic process, positive regulation of apoptotic signaling pathway, positive regulation of cell morphogenesis involved in differentiation, positive regulation of chemokine production, positive regulation of gene expression, positive regulation of macrophage derived foam cell differentiation, positive regulation of nitric oxide biosynthetic process, positive regulation of nitric-oxide synthase biosynthetic process, positive regulation of prostaglandin biosynthetic process, positive regulation of prostaglandin secretion, positive regulation of protein phosphorylation, positive regulation of transcription, DNA-dependent, protein targeting to mitochondrion, regulation of JNK cascade, regulation of protein ubiquitination, regulation of sequence-specific DNA binding transcription factor activity, release of cytochrome c from mitochondria, response to amine stimulus, response to cadmium ion, response to drug, response to mechanical stimulus, response to stress, response to toxic substance, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway cytosol, cytosolic part, mitochondrion, nucleoplasm, nucleus ATP binding, JUN kinase activity, MAP kinase activity, cysteine-type endopeptidase activator activity involved in apoptotic process, kinase activity, mitogen-activated protein kinase kinase kinase binding, protein binding, transcription factor binding Human MAPKAP1 Reactome UniProtKB {GO:0048011=Reactome:REACT_11061, GO:0070300=PMID:17303383, GO:0005794=PMID:17303383, GO:0005886=PMID:17303383, GO:0048015=Reactome:REACT_12464, GO:0043325=PMID:17303383, GO:0031295=Reactome:REACT_19344, GO:0005547=PMID:17303383, GO:0080025=PMID:17303383, GO:0005546=PMID:17303383, GO:0005634=GO_REF:0000039, GO:0005829=Reactome:REACT_147858, GO:0046580=PMID:17303383, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9470, GO:0016301=GO_REF:0000038, GO:0045087=Reactome:REACT_6802, GO:0016023=GO_REF:0000039, GO:0017016=PMID:17303383} Q9BPZ7 Target of rapamycin complex 2 subunit MAPKAP1 protein 20130131 {GO:0048011=TAS, GO:0070300=IDA, GO:0005794=IDA, GO:0005886=IDA, GO:0048015=TAS, GO:0043325=IDA, GO:0031295=TAS, GO:0005547=IDA, GO:0080025=IDA, GO:0005546=IDA, GO:0005634=IEA, GO:0005829=TAS, GO:0046580=IMP, GO:0007173=TAS, GO:0008543=TAS, GO:0016301=IEA, GO:0045087=TAS, GO:0016023=IEA, GO:0017016=IDA} T cell costimulation, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, negative regulation of Ras protein signal transduction, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling Golgi apparatus, cytoplasmic membrane-bounded vesicle, cytosol, nucleus, plasma membrane Ras GTPase binding, kinase activity, phosphatidic acid binding, phosphatidylinositol-3,4,5-trisphosphate binding, phosphatidylinositol-3,4-bisphosphate binding, phosphatidylinositol-3,5-bisphosphate binding, phosphatidylinositol-4,5-bisphosphate binding Human MAPKAPK2 BHF-UCL UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0005515=PMID:23455922, GO:0010467=Reactome:REACT_71, GO:0034142=Reactome:REACT_6894, GO:0031572=PMID:20932473, GO:0007265=Reactome:REACT_12033, GO:0005634=PMID:20932473, GO:0044281=Reactome:REACT_111217, GO:0051403=Reactome:REACT_21308, GO:0006691=Reactome:REACT_150420, GO:0005829=Reactome:REACT_25285, GO:0000187=Reactome:REACT_21399, GO:0002756=Reactome:REACT_6809, GO:0005737=PMID:20932473, GO:0006954=GO_REF:0000024, GO:0018105=PMID:15850461, GO:0000165=PMID:8179591, GO:0002755=Reactome:REACT_27215, GO:0032496=GO_REF:0000024, GO:0004871=PMID:8179591, GO:0034138=Reactome:REACT_6783, GO:0048011=Reactome:REACT_11061, GO:0048839=GO_REF:0000019, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0032680=PMID:15014438, GO:0034134=Reactome:REACT_7980, GO:0006950=PMID:8774846, GO:0002224=Reactome:REACT_9020, GO:0005524=GO_REF:0000037, GO:0006974=PMID:20932473, GO:0044351=GO_REF:0000024, GO:0004672=PMID:8179591, GO:0004674=PMID:20932473, GO:0045087=Reactome:REACT_6802, GO:0035666=Reactome:REACT_25281, GO:0034166=Reactome:REACT_9027, GO:0006468=PMID:8179591, GO:0005654=Reactome:REACT_21395, GO:0032675=GO_REF:0000024, GO:0034146=Reactome:REACT_9061, GO:0070935=PMID:20932473, GO:0034162=Reactome:REACT_9047} P49137 MAP kinase-activated protein kinase 2 protein 20120123 {GO:0019369=TAS, GO:0005515=IPI, GO:0010467=TAS, GO:0034142=TAS, GO:0031572=IMP, GO:0007265=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0051403=TAS, GO:0006691=TAS, GO:0005829=TAS, GO:0000187=TAS, GO:0002756=TAS, GO:0005737=IDA, GO:0006954=ISS, GO:0018105=IDA, GO:0000165=TAS, GO:0002755=TAS, GO:0032496=ISS, GO:0004871=TAS, GO:0034138=TAS, GO:0048011=TAS, GO:0048839=IEA, GO:0038124=TAS, GO:0038123=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0032680=IDA, GO:0034134=TAS, GO:0006950=IDA, GO:0002224=TAS, GO:0005524=IEA, GO:0006974=IMP, GO:0044351=ISS, GO:0004672=TAS, GO:0004674=IDA, GO:0045087=TAS, GO:0035666=TAS, GO:0034166=TAS, GO:0006468=TAS, GO:0005654=TAS, GO:0032675=ISS, GO:0034146=TAS, GO:0070935=IDA, GO:0034162=TAS} 3'-UTR-mediated mRNA stabilization, G2 DNA damage checkpoint, MAPK cascade, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, RNA metabolic process, Ras protein signal transduction, TRIF-dependent toll-like receptor signaling pathway, activation of MAPK activity, arachidonic acid metabolic process, gene expression, inflammatory response, innate immune response, inner ear development, leukotriene metabolic process, mRNA metabolic process, macropinocytosis, neurotrophin TRK receptor signaling pathway, peptidyl-serine phosphorylation, protein phosphorylation, regulation of interleukin-6 production, regulation of tumor necrosis factor production, response to DNA damage stimulus, response to lipopolysaccharide, response to stress, small molecule metabolic process, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway cytoplasm, cytosol, nucleoplasm, nucleus ATP binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, signal transducer activity Human MAPKAPK3 BHF-UCL UniProtKB {GO:0005515=PMID:21575178, GO:0034142=Reactome:REACT_6894, GO:0005634=PMID:10781029, GO:0007265=Reactome:REACT_12033, GO:0051403=Reactome:REACT_21308, GO:0005829=Reactome:REACT_21358, GO:0000187=Reactome:REACT_21399, GO:0002756=Reactome:REACT_6809, GO:0018105=PMID:15850461, GO:0002755=Reactome:REACT_27215, GO:0032496=GO_REF:0000024, GO:0034138=Reactome:REACT_6783, GO:0004708=PMID:10781029, GO:0016772=GO_REF:0000002, GO:0048011=Reactome:REACT_11061, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0006950=PMID:8774846, GO:0002224=Reactome:REACT_9020, GO:0005524=GO_REF:0000037, GO:0007165=PMID:8626550, GO:0004672=GO_REF:0000002, GO:0044351=GO_REF:0000024, GO:0004674=PMID:8774846, GO:0045087=Reactome:REACT_6802, GO:0034166=Reactome:REACT_9027, GO:0005654=Reactome:REACT_21395, GO:0035666=Reactome:REACT_25281, GO:0034146=Reactome:REACT_9061, GO:0034162=Reactome:REACT_9047} Q16644 MAP kinase-activated protein kinase 3 protein 20120123 {GO:0005515=IPI, GO:0034142=TAS, GO:0005634=TAS, GO:0007265=TAS, GO:0051403=TAS, GO:0005829=TAS, GO:0000187=TAS, GO:0002756=TAS, GO:0018105=IDA, GO:0002755=TAS, GO:0032496=ISS, GO:0034138=TAS, GO:0004708=TAS, GO:0016772=IEA, GO:0048011=TAS, GO:0038124=TAS, GO:0038123=TAS, GO:0034134=TAS, GO:0006950=IDA, GO:0002224=TAS, GO:0005524=IEA, GO:0007165=TAS, GO:0004672=IEA, GO:0044351=ISS, GO:0004674=IDA, GO:0045087=TAS, GO:0034166=TAS, GO:0005654=TAS, GO:0035666=TAS, GO:0034146=TAS, GO:0034162=TAS} MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, Ras protein signal transduction, TRIF-dependent toll-like receptor signaling pathway, activation of MAPK activity, innate immune response, macropinocytosis, neurotrophin TRK receptor signaling pathway, peptidyl-serine phosphorylation, response to lipopolysaccharide, response to stress, signal transduction, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway cytosol, nucleoplasm, nucleus ATP binding, MAP kinase kinase activity, protein binding, protein kinase activity, protein serine/threonine kinase activity, transferase activity, transferring phosphorus-containing groups Human MAPKAPK5 GOC UniProtKB {GO:0005515=PMID:21575178, GO:0032007=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0006950=PMID:21329882, GO:0005634=GO_REF:0000052, GO:0007265=PMID:17254968, GO:0090400=PMID:17254968, GO:0005524=GO_REF:0000037, GO:0006417=PMID:21329882, GO:0000187=PMID:9628874, GO:0007165=PMID:9628874, GO:0002039=PMID:17254968, GO:0005737=GO_REF:0000052, GO:0046777=PMID:21329882, GO:0004672=GO_REF:0000019, GO:0000165=PMID:9628874, GO:0004674=PMID:17254968, GO:0004708=PMID:9628874, GO:0051019=GO_REF:0000019} Q8IW41 MAP kinase-activated protein kinase 5 protein 20130413 {GO:0005515=IPI, GO:0032007=ISS, GO:0005730=IDA, GO:0006950=IDA, GO:0005634=IDA, GO:0007265=IDA, GO:0090400=IDA, GO:0005524=IEA, GO:0006417=IDA, GO:0000187=TAS, GO:0007165=TAS, GO:0002039=IDA, GO:0005737=IDA, GO:0046777=IDA, GO:0004672=IEA, GO:0000165=TAS, GO:0004674=IDA, GO:0004708=TAS, GO:0051019=IEA} MAPK cascade, Ras protein signal transduction, activation of MAPK activity, negative regulation of TOR signaling cascade, protein autophosphorylation, regulation of translation, response to stress, signal transduction, stress-induced premature senescence cytoplasm, nucleolus, nucleus ATP binding, MAP kinase kinase activity, mitogen-activated protein kinase binding, p53 binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human MAPKBP1 ENSEMBL UniProtKB {GO:0007256=GO_REF:0000019} O60336 Mitogen-activated protein kinase-binding protein 1 protein 20130413 {GO:0007256=IEA} activation of JNKK activity Human Ensembl:ENSMUSP00000068516 MAPRE1 HPA UniProtKB {GO:0005515=PMID:19632184, GO:0000236=Reactome:REACT_682, GO:0005881=GO_REF:0000019, GO:0031253=GO_REF:0000019, GO:0031115=PMID:11943150, GO:0005813=GO_REF:0000052, GO:0005794=GO_REF:0000019, GO:0030981=PMID:15631994, GO:0008283=PMID:7606712, GO:0005874=PMID:10773885, GO:0005819=PMID:11943150, GO:0035372=PMID:19632184, GO:0035371=GO_REF:0000019, GO:0008022=PMID:7606712, GO:0005829=Reactome:REACT_150414, GO:0005737=GO_REF:0000052, GO:0051010=PMID:19632184, GO:0000086=Reactome:REACT_2203, GO:0000087=Reactome:REACT_910, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q15691 Microtubule-associated protein RP/EB family member 1 protein 20101115 {GO:0005515=IPI, GO:0000236=TAS, GO:0005881=IEA, GO:0031253=IEA, GO:0031115=IDA, GO:0005813=IDA, GO:0005794=IEA, GO:0030981=IDA, GO:0008283=TAS, GO:0005874=IDA, GO:0005819=IDA, GO:0035372=IDA, GO:0035371=IEA, GO:0008022=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0051010=IDA, GO:0000086=TAS, GO:0000087=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, cell division, cell proliferation, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, negative regulation of microtubule polymerization, protein localization to microtubule Golgi apparatus, cell projection membrane, centrosome, cortical microtubule cytoskeleton, cytoplasm, cytoplasmic microtubule, cytosol, microtubule, microtubule plus end, spindle microtubule plus-end binding, protein C-terminus binding, protein binding Human MAPRE2 LIFEdb UniProtKB {GO:0008017=GO_REF:0000002, GO:0007165=PMID:9233623, GO:0007067=GO_REF:0000037, GO:0005737=GO_REF:0000037, GO:0008283=PMID:9233623, GO:0015630=GO_REF:0000054, GO:0005874=GO_REF:0000037, GO:0051301=GO_REF:0000037} Q15555 Microtubule-associated protein RP/EB family member 2 protein 20100607 {GO:0008017=IEA, GO:0007165=TAS, GO:0007067=IEA, GO:0005737=IEA, GO:0008283=TAS, GO:0015630=IDA, GO:0005874=IEA, GO:0051301=IEA} cell division, cell proliferation, mitosis, signal transduction cytoplasm, microtubule, microtubule cytoskeleton microtubule binding Human MAPRE3 HPA UniProtKB {GO:0005515=PMID:20195357, GO:0008017=PMID:17310996, GO:0005083=GO_REF:0000029, GO:0007067=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0007049=PMID:17310996, GO:0005874=PMID:17310996, GO:0030496=PMID:17310996, GO:0045893=PMID:17310996, GO:0051301=GO_REF:0000037} Q9UPY8 Microtubule-associated protein RP/EB family member 3 protein 20080205 {GO:0005515=IPI, GO:0008017=ISS, GO:0005083=NAS, GO:0007067=IEA, GO:0005737=IDA, GO:0007049=ISS, GO:0005874=ISS, GO:0030496=ISS, GO:0045893=ISS, GO:0051301=IEA} cell cycle, cell division, mitosis, positive regulation of transcription, DNA-dependent cytoplasm, microtubule, midbody microtubule binding, protein binding, small GTPase regulator activity Human MAPT BHF-UCL UniProtKB {GO:0008017=PMID:1918161, GO:0005515=PMID:17317006, GO:0030424=PMID:8642405, GO:0017124=PMID:9763511, GO:0005886=PMID:8522593, GO:0048699=PMID:8522593, GO:0045773=PMID:1389180, GO:0007409=GO_REF:0000019, GO:0035085=GO_REF:0000019, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_13414, GO:0030426=PMID:8642405, GO:0047497=GO_REF:0000019, GO:0007628=GO_REF:0000019, GO:0045298=PMID:8642405, GO:0071813=PMID:7972031, GO:0031116=PMID:1421571, GO:0032387=GO_REF:0000019, GO:0019901=GO_REF:0000019, GO:0005875=PMID:10747907, GO:0005874=GO_REF:0000019, GO:0031113=PMID:1057175, GO:0006915=Reactome:REACT_578, GO:0000226=PMID:1057175, GO:0060632=GO_REF:0000019, GO:0034399=PMID:19157893, GO:0005200=PMID:2498079, GO:0010506=PMID:19074461, GO:0008088=GO_REF:0000019, GO:0034185=PMID:7566652, GO:0001764=GO_REF:0000019, GO:0019899=PMID:20133804} P10636 Microtubule-associated protein tau protein 20120508 {GO:0008017=IDA, GO:0005515=IPI, GO:0030424=IDA, GO:0017124=IPI, GO:0005886=IDA, GO:0048699=NAS, GO:0045773=IDA, GO:0007409=IEA, GO:0035085=IEA, GO:0006921=TAS, GO:0005829=TAS, GO:0030426=IDA, GO:0047497=IEA, GO:0007628=IEA, GO:0045298=IDA, GO:0071813=IPI, GO:0031116=IDA, GO:0032387=IEA, GO:0019901=IEA, GO:0005875=TAS, GO:0005874=IEA, GO:0031113=NAS, GO:0006915=TAS, GO:0000226=IDA, GO:0060632=IEA, GO:0034399=IDA, GO:0005200=TAS, GO:0010506=IGI, GO:0008088=IEA, GO:0034185=IPI, GO:0001764=IEA, GO:0019899=IPI} adult walking behavior, apoptotic process, axon cargo transport, axonogenesis, cellular component disassembly involved in execution phase of apoptosis, generation of neurons, microtubule cytoskeleton organization, mitochondrion transport along microtubule, negative regulation of intracellular transport, neuron migration, positive regulation of axon extension, positive regulation of microtubule polymerization, regulation of autophagy, regulation of microtubule polymerization, regulation of microtubule-based movement axon, cilium axoneme, cytosol, growth cone, microtubule, microtubule associated complex, nuclear periphery, plasma membrane, tubulin complex SH3 domain binding, apolipoprotein binding, enzyme binding, lipoprotein particle binding, microtubule binding, protein binding, protein kinase binding, structural constituent of cytoskeleton Human UniProtKB:P02649 MARC1 UniProtKB UniProtKB {GO:0005739=PMID:20861021, GO:0043546=PMID:20861021, GO:0051410=PMID:20861021, GO:0042126=PMID:20861021, GO:0008940=PMID:20861021, GO:0030170=GO_REF:0000002, GO:0005743=GO_REF:0000019, GO:0005741=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0003824=GO_REF:0000002, GO:0055114=PMID:20861021, GO:0030151=PMID:20861021} Q5VT66 MOSC domain-containing protein 1, mitochondrial protein 20111031 {GO:0005739=ISS, GO:0043546=IDA, GO:0051410=NAS, GO:0042126=IDA, GO:0008940=IDA, GO:0030170=IEA, GO:0005743=IEA, GO:0005741=IEA, GO:0016021=IEA, GO:0003824=IEA, GO:0055114=IDA, GO:0030151=IDA} detoxification of nitrogen compound, nitrate metabolic process, oxidation-reduction process integral to membrane, mitochondrial inner membrane, mitochondrial outer membrane, mitochondrion catalytic activity, molybdenum ion binding, molybdopterin cofactor binding, nitrate reductase activity, pyridoxal phosphate binding Human MARC2 LIFEdb UniProtKB {GO:0005739=GO_REF:0000054, GO:0043546=PMID:20861021, GO:0051410=PMID:20861021, GO:0042126=PMID:20861021, GO:0008940=PMID:20861021, GO:0030170=GO_REF:0000002, GO:0005743=GO_REF:0000019, GO:0005741=GO_REF:0000039, GO:0055114=PMID:20861021, GO:0030151=PMID:20861021, GO:0005777=GO_REF:0000039} Q969Z3 MOSC domain-containing protein 2, mitochondrial protein 20100607 {GO:0005739=IDA, GO:0043546=IDA, GO:0051410=NAS, GO:0042126=IDA, GO:0008940=IDA, GO:0030170=IEA, GO:0005743=IEA, GO:0005741=IEA, GO:0055114=IDA, GO:0030151=IDA, GO:0005777=IEA} detoxification of nitrogen compound, nitrate metabolic process, oxidation-reduction process mitochondrial inner membrane, mitochondrial outer membrane, mitochondrion, peroxisome molybdenum ion binding, molybdopterin cofactor binding, nitrate reductase activity, pyridoxal phosphate binding Human MARCH1 UniProtKB UniProtKB {GO:0042287=PMID:18389477, GO:0000209=PMID:19117940, GO:0004842=PMID:18389477, GO:0005794=GO_REF:0000039, GO:0005886=PMID:19117940, GO:0002495=PMID:18389477, GO:0005765=GO_REF:0000024, GO:0005764=PMID:14722266, GO:0032588=GO_REF:0000024, GO:0006955=PMID:18389477, GO:0031901=PMID:19117940, GO:0031902=PMID:19117940, GO:0005789=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0030659=GO_REF:0000039, GO:0005768=PMID:14722266} Q8TCQ1 E3 ubiquitin-protein ligase MARCH1 protein 20110616 {GO:0042287=IDA, GO:0000209=IDA, GO:0004842=IDA, GO:0005794=IEA, GO:0005886=IDA, GO:0002495=IDA, GO:0005765=ISS, GO:0005764=IDA, GO:0032588=ISS, GO:0006955=IDA, GO:0031901=IDA, GO:0031902=IDA, GO:0005789=ISS, GO:0008270=IEA, GO:0016021=IEA, GO:0030659=IEA, GO:0005768=IDA} antigen processing and presentation of peptide antigen via MHC class II, immune response, protein polyubiquitination Golgi apparatus, cytoplasmic vesicle membrane, early endosome membrane, endoplasmic reticulum membrane, endosome, integral to membrane, late endosome membrane, lysosomal membrane, lysosome, plasma membrane, trans-Golgi network membrane MHC protein binding, ubiquitin-protein ligase activity, zinc ion binding Human MARCH10 UniPathway UniProtKB {GO:0016567=GO_REF:0000041, GO:0016874=GO_REF:0000037, GO:0008270=GO_REF:0000002} Q8NA82 Probable E3 ubiquitin-protein ligase MARCH10 protein 20130413 {GO:0016567=IEA, GO:0016874=IEA, GO:0008270=IEA} protein ubiquitination ligase activity, zinc ion binding Human UniPathway:UPA00143 MARCH2 UniProtKB UniProtKB {GO:0004842=PMID:14722266, GO:0016567=PMID:14722266, GO:0005783=PMID:14722266, GO:0005789=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0031410=PMID:14722266, GO:0016021=GO_REF:0000037, GO:0005765=GO_REF:0000039, GO:0010008=GO_REF:0000039, GO:0006897=GO_REF:0000037} Q9P0N8 E3 ubiquitin-protein ligase MARCH2 protein 20101213 {GO:0004842=IDA, GO:0016567=IDA, GO:0005783=IDA, GO:0005789=IEA, GO:0008270=IEA, GO:0031410=IDA, GO:0016021=IEA, GO:0005765=IEA, GO:0010008=IEA, GO:0006897=IEA} endocytosis, protein ubiquitination cytoplasmic vesicle, endoplasmic reticulum, endoplasmic reticulum membrane, endosome membrane, integral to membrane, lysosomal membrane ubiquitin-protein ligase activity, zinc ion binding Human MARCH3 UniProtKB UniProtKB {GO:0016567=GO_REF:0000041, GO:0031901=GO_REF:0000039, GO:0016874=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005764=PMID:14722266, GO:0030659=GO_REF:0000039, GO:0005768=PMID:14722266, GO:0006897=GO_REF:0000037} Q86UD3 E3 ubiquitin-protein ligase MARCH3 protein 20101203 {GO:0016567=IEA, GO:0031901=IEA, GO:0016874=IEA, GO:0008270=IEA, GO:0016021=IEA, GO:0005764=IDA, GO:0030659=IEA, GO:0005768=IDA, GO:0006897=IEA} endocytosis, protein ubiquitination cytoplasmic vesicle membrane, early endosome membrane, endosome, integral to membrane, lysosome ligase activity, zinc ion binding Human MARCH4 UniProtKB UniProtKB {GO:0005802=PMID:14722266, GO:0004842=PMID:14722266, GO:0005795=PMID:14722266, GO:0000139=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q9P2E8 E3 ubiquitin-protein ligase MARCH4 protein 20101203 {GO:0005802=IDA, GO:0004842=IDA, GO:0005795=IDA, GO:0000139=IEA, GO:0008270=IEA, GO:0016021=IEA} Golgi membrane, Golgi stack, integral to membrane, trans-Golgi network ubiquitin-protein ligase activity, zinc ion binding Human MARCH5 UniProtKB UniProtKB {GO:0000209=PMID:16936636, GO:0005515=PMID:16874301, GO:0004842=PMID:16874301, GO:0005783=PMID:14722266, GO:0090344=PMID:20103533, GO:0005741=PMID:16874301, GO:0090141=PMID:20103533, GO:0090140=PMID:16874301, GO:0051865=PMID:16874301, GO:0051020=PMID:16936636, GO:0070585=PMID:17606867, GO:0005789=PMID:14722266, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q9NX47 E3 ubiquitin-protein ligase MARCH5 protein 20110719 {GO:0000209=IDA, GO:0005515=IPI, GO:0004842=IMP, GO:0005783=IDA, GO:0090344=IMP, GO:0005741=IDA, GO:0090141=IMP, GO:0090140=IMP, GO:0051865=IDA, GO:0051020=IPI, GO:0070585=IMP, GO:0005789=IDA, GO:0008270=IEA, GO:0016021=IEA} negative regulation of cell aging, positive regulation of mitochondrial fission, protein autoubiquitination, protein localization to mitochondrion, protein polyubiquitination, regulation of mitochondrial fission endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, mitochondrial outer membrane GTPase binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human MARCH6 UniProtKB UniProtKB {GO:0004842=PMID:19651899, GO:0030176=PMID:15673284, GO:0008270=GO_REF:0000002, GO:0019899=PMID:19651899, GO:0070936=PMID:15673284, GO:0031624=PMID:15673284} O60337 E3 ubiquitin-protein ligase MARCH6 protein 20101005 {GO:0004842=IMP, GO:0030176=IDA, GO:0008270=IEA, GO:0019899=IPI, GO:0070936=IDA, GO:0031624=IPI} protein K48-linked ubiquitination integral to endoplasmic reticulum membrane enzyme binding, ubiquitin conjugating enzyme binding, ubiquitin-protein ligase activity, zinc ion binding Human MARCH7 UniPathway UniProtKB {GO:0016567=GO_REF:0000041, GO:0016874=GO_REF:0000037, GO:0008270=GO_REF:0000002} Q9H992 E3 ubiquitin-protein ligase MARCH7 protein 20130413 {GO:0016567=IEA, GO:0016874=IEA, GO:0008270=IEA} protein ubiquitination ligase activity, zinc ion binding Human UniPathway:UPA00143 MARCH8 UniProtKB UniProtKB {GO:0000209=PMID:19117940, GO:0004842=PMID:19117940, GO:0042289=GO_REF:0000019, GO:0002495=GO_REF:0000019, GO:0031901=GO_REF:0000039, GO:0045347=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005765=GO_REF:0000039, GO:0005764=PMID:14722266, GO:0030659=GO_REF:0000039, GO:0005768=PMID:14722266} Q5T0T0 E3 ubiquitin-protein ligase MARCH8 protein 20110715 {GO:0000209=IDA, GO:0004842=IDA, GO:0042289=IEA, GO:0002495=IEA, GO:0031901=IEA, GO:0045347=IEA, GO:0008270=IEA, GO:0016021=IEA, GO:0005765=IEA, GO:0005764=IDA, GO:0030659=IEA, GO:0005768=IDA} antigen processing and presentation of peptide antigen via MHC class II, negative regulation of MHC class II biosynthetic process, protein polyubiquitination cytoplasmic vesicle membrane, early endosome membrane, endosome, integral to membrane, lysosomal membrane, lysosome MHC class II protein binding, ubiquitin-protein ligase activity, zinc ion binding Human MARCH9 UniProtKB UniProtKB {GO:0005802=PMID:14722266, GO:0016567=GO_REF:0000041, GO:0005795=PMID:14722266, GO:0000139=GO_REF:0000039, GO:0016874=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005765=GO_REF:0000039} Q86YJ5 E3 ubiquitin-protein ligase MARCH9 protein 20101203 {GO:0005802=IDA, GO:0016567=IEA, GO:0005795=IDA, GO:0000139=IEA, GO:0016874=IEA, GO:0008270=IEA, GO:0016021=IEA, GO:0005765=IEA} protein ubiquitination Golgi membrane, Golgi stack, integral to membrane, lysosomal membrane, trans-Golgi network ligase activity, zinc ion binding Human MARCKS Reactome UniProtKB {GO:0005516=GO_REF:0000037, GO:0005813=GO_REF:0000019, GO:0006112=Reactome:REACT_1505, GO:0051015=PMID:1560845, GO:0050796=Reactome:REACT_18325, GO:0005886=Reactome:REACT_18263, GO:0042585=GO_REF:0000019, GO:0005080=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0015629=PMID:1560845, GO:0005938=GO_REF:0000019} P29966 Myristoylated alanine-rich C-kinase substrate protein 20130301 {GO:0005516=IEA, GO:0005813=IEA, GO:0006112=TAS, GO:0051015=TAS, GO:0050796=TAS, GO:0005886=TAS, GO:0042585=IEA, GO:0005080=IEA, GO:0044281=TAS, GO:0015629=TAS, GO:0005938=IEA} energy reserve metabolic process, regulation of insulin secretion, small molecule metabolic process actin cytoskeleton, cell cortex, centrosome, germinal vesicle, plasma membrane actin filament binding, calmodulin binding, protein kinase C binding Human MARCKSL1 LIFEdb UniProtKB {GO:0005516=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0008284=GO_REF:0000019, GO:0005886=GO_REF:0000054, GO:0003779=GO_REF:0000037} P49006 MARCKS-related protein protein 20100607 {GO:0005516=IEA, GO:0005737=IEA, GO:0008284=IEA, GO:0005886=IDA, GO:0003779=IEA} positive regulation of cell proliferation cytoplasm, plasma membrane actin binding, calmodulin binding Human MARCO GOC UniProtKB {GO:0002221=PMID:10331948, GO:0005581=GO_REF:0000037, GO:0016020=GO_REF:0000002, GO:0005887=PMID:9468508, GO:0045087=GO_REF:0000037, GO:0007166=PMID:9468508, GO:0008329=PMID:10331948, GO:0004888=PMID:10331948, GO:0005044=GO_REF:0000002} Q9UEW3 Macrophage receptor MARCO protein 20130413 {GO:0002221=TAS, GO:0005581=IEA, GO:0016020=IEA, GO:0005887=TAS, GO:0045087=IEA, GO:0007166=TAS, GO:0008329=TAS, GO:0004888=TAS, GO:0005044=IEA} cell surface receptor signaling pathway, innate immune response, pattern recognition receptor signaling pathway collagen, integral to plasma membrane, membrane pattern recognition receptor activity, scavenger receptor activity, transmembrane signaling receptor activity Human MARK1 PINC UniProtKB {GO:0070300=PMID:21145462, GO:0000287=PMID:14976552, GO:0005886=PMID:21145462, GO:0050321=GO_REF:0000024, GO:0000226=GO_REF:0000019, GO:0005546=PMID:21145462, GO:0005524=PMID:14976552, GO:0007243=PMID:14976552, GO:0005737=GO_REF:0000024, GO:0004674=PMID:14976552, GO:0015630=PMID:9108484, GO:0007010=GO_REF:0000024, GO:0001786=PMID:21145462, GO:0006468=PMID:14976552, GO:0001764=GO_REF:0000024, GO:0016055=GO_REF:0000037, GO:0005856=GO_REF:0000024} Q9P0L2 Serine/threonine-protein kinase MARK1 protein 20061106 {GO:0070300=IDA, GO:0000287=IDA, GO:0005886=IDA, GO:0050321=ISS, GO:0000226=IEA, GO:0005546=IDA, GO:0005524=IDA, GO:0007243=IDA, GO:0005737=ISS, GO:0004674=IDA, GO:0015630=TAS, GO:0007010=ISS, GO:0001786=IDA, GO:0006468=IDA, GO:0001764=ISS, GO:0016055=IEA, GO:0005856=ISS} Wnt receptor signaling pathway, cytoskeleton organization, intracellular protein kinase cascade, microtubule cytoskeleton organization, neuron migration, protein phosphorylation cytoplasm, cytoskeleton, microtubule cytoskeleton, plasma membrane ATP binding, magnesium ion binding, phosphatidic acid binding, phosphatidylinositol-4,5-bisphosphate binding, phosphatidylserine binding, protein serine/threonine kinase activity, tau-protein kinase activity Human MARK2 BHF-UCL UniProtKB {GO:0005515=PMID:19615732, GO:0000287=PMID:14976552, GO:0045180=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0050321=GO_REF:0000024, GO:0030010=PMID:16775013, GO:0005634=GO_REF:0000019, GO:0005524=PMID:14976552, GO:0007243=PMID:14976552, GO:0045197=PMID:15324659, GO:0008289=GO_REF:0000037, GO:0046777=GO_REF:0000024, GO:0016020=PMID:14976552, GO:0051493=GO_REF:0000024, GO:0004674=PMID:20194617, GO:0016301=GO_REF:0000038, GO:0010976=PMID:12429843, GO:0006468=PMID:14976552, GO:0001764=GO_REF:0000024, GO:0016055=GO_REF:0000037, GO:0006979=PMID:16551573, GO:0050770=PMID:20194617} Q7KZI7 Serine/threonine-protein kinase MARK2 protein 20091104 {GO:0005515=IPI, GO:0000287=IDA, GO:0045180=IEA, GO:0005886=IEA, GO:0050321=ISS, GO:0030010=TAS, GO:0005634=IEA, GO:0005524=IDA, GO:0007243=IDA, GO:0045197=IDA, GO:0008289=IEA, GO:0046777=ISS, GO:0016020=IMP, GO:0051493=ISS, GO:0004674=IDA, GO:0016301=IEA, GO:0010976=IDA, GO:0006468=IDA, GO:0001764=ISS, GO:0016055=IEA, GO:0006979=IEP, GO:0050770=IMP} Wnt receptor signaling pathway, establishment of cell polarity, establishment or maintenance of epithelial cell apical/basal polarity, intracellular protein kinase cascade, neuron migration, positive regulation of neuron projection development, protein autophosphorylation, protein phosphorylation, regulation of axonogenesis, regulation of cytoskeleton organization, response to oxidative stress basal cortex, membrane, nucleus, plasma membrane ATP binding, kinase activity, lipid binding, magnesium ion binding, protein binding, protein serine/threonine kinase activity, tau-protein kinase activity Human MARK3 IntAct UniProtKB {GO:0005515=PMID:17979178, GO:0004672=GO_REF:0000002, GO:0005886=PMID:21145462, GO:0004674=PMID:16980613, GO:0016301=GO_REF:0000038, GO:0005524=GO_REF:0000037} P27448 MAP/microtubule affinity-regulating kinase 3 protein 20130415 {GO:0005515=IPI, GO:0004672=IEA, GO:0005886=IDA, GO:0004674=IDA, GO:0016301=IEA, GO:0005524=IEA} plasma membrane ATP binding, kinase activity, protein binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB:Q04917 MARK4 IntAct UniProtKB {GO:0005515=PMID:16959763, GO:0008017=PMID:14594945, GO:0043005=PMID:14594945, GO:0043130=PMID:14594945, GO:0005813=PMID:14594945, GO:0043015=PMID:14594945, GO:0005815=PMID:14594945, GO:0001578=PMID:14594945, GO:0050321=PMID:14594945, GO:0000226=PMID:14594945, GO:0005524=PMID:15009667, GO:0007399=PMID:14594945, GO:0043068=PMID:15009667, GO:0004672=GO_REF:0000002, GO:0004674=PMID:15009667, GO:0015630=PMID:14594945, GO:0006468=PMID:14594945} Q96L34 MAP/microtubule affinity-regulating kinase 4 protein 20130415 {GO:0005515=IPI, GO:0008017=IDA, GO:0043005=IDA, GO:0043130=NAS, GO:0005813=IDA, GO:0043015=IDA, GO:0005815=IDA, GO:0001578=IEP, GO:0050321=IDA, GO:0000226=IMP, GO:0005524=NAS, GO:0007399=IDA, GO:0043068=NAS, GO:0004672=IEA, GO:0004674=IDA, GO:0015630=IDA, GO:0006468=TAS} microtubule bundle formation, microtubule cytoskeleton organization, nervous system development, positive regulation of programmed cell death, protein phosphorylation centrosome, microtubule cytoskeleton, microtubule organizing center, neuron projection ATP binding, gamma-tubulin binding, microtubule binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, tau-protein kinase activity, ubiquitin binding Human UniProtKB:Q04917 MARS HPA UniProtKB {GO:0005739=GO_REF:0000019, GO:0010467=Reactome:REACT_71, GO:0005737=GO_REF:0000052, GO:0000049=GO_REF:0000037, GO:0006431=GO_REF:0000002, GO:0004825=Reactome:REACT_15420, GO:0005524=GO_REF:0000037, GO:0004812=GO_REF:0000002, GO:0005829=Reactome:REACT_15516, GO:0006418=Reactome:REACT_15482} P56192 Methionine--tRNA ligase, cytoplasmic protein 20100326 {GO:0005739=IEA, GO:0010467=TAS, GO:0005737=IDA, GO:0000049=IEA, GO:0006431=IEA, GO:0004825=TAS, GO:0005524=IEA, GO:0004812=IEA, GO:0005829=TAS, GO:0006418=TAS} gene expression, methionyl-tRNA aminoacylation, tRNA aminoacylation for protein translation cytoplasm, cytosol, mitochondrion ATP binding, aminoacyl-tRNA ligase activity, methionine-tRNA ligase activity, tRNA binding Human MARS2 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0006431=PMID:15274629, GO:0005759=Reactome:REACT_15446, GO:0004825=PMID:15274629, GO:0005524=GO_REF:0000037, GO:0006418=Reactome:REACT_15482} Q96GW9 Methionine--tRNA ligase, mitochondrial protein 20130301 {GO:0010467=TAS, GO:0006431=IDA, GO:0005759=TAS, GO:0004825=IDA, GO:0005524=IEA, GO:0006418=TAS} gene expression, methionyl-tRNA aminoacylation, tRNA aminoacylation for protein translation mitochondrial matrix ATP binding, methionine-tRNA ligase activity Human MARVELD1 UniProtKB UniProtKB {GO:0007049=GO_REF:0000037, GO:0005737=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0005856=GO_REF:0000039} Q9BSK0 MARVEL domain-containing protein 1 protein 20130413 {GO:0007049=IEA, GO:0005737=IEA, GO:0005886=IEA, GO:0005634=IEA, GO:0016021=IEA, GO:0005856=IEA} cell cycle cytoplasm, cytoskeleton, integral to membrane, nucleus, plasma membrane Human UniProtKB-SubCell:SL-0039 MARVELD2 MGI UniProtKB {GO:0043220=GO_REF:0000019, GO:0033010=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0007605=PMID:17186462, GO:0005923=PMID:20164257, GO:0016021=GO_REF:0000037, GO:0045216=PMID:20164257} Q8N4S9 MARVEL domain-containing protein 2 protein 20120514 {GO:0043220=IEA, GO:0033010=IEA, GO:0005886=IEA, GO:0007605=IMP, GO:0005923=IDA, GO:0016021=IEA, GO:0045216=IMP} cell-cell junction organization, sensory perception of sound Schmidt-Lanterman incisure, integral to membrane, paranodal junction, plasma membrane, tight junction Human MARVELD3 MGI UniProtKB {GO:0005923=PMID:20164257, GO:0016021=GO_REF:0000037, GO:0045216=PMID:20164257} Q96A59 MARVEL domain-containing protein 3 protein 20120514 {GO:0005923=IDA, GO:0016021=IEA, GO:0045216=IMP} cell-cell junction organization integral to membrane, tight junction Human MAS1 PINC UniProtKB {GO:0008284=GO_REF:0000019, GO:0004945=PMID:3419518, GO:0005886=PMID:16611642, GO:0008283=PMID:3419518, GO:0060732=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0009653=PMID:8661154, GO:0071375=GO_REF:0000019, GO:0014823=GO_REF:0000019, GO:0042277=GO_REF:0000024, GO:0009986=GO_REF:0000019, GO:0007250=GO_REF:0000019, GO:0004930=PMID:16611642, GO:0042493=GO_REF:0000019, GO:0045740=GO_REF:0000019, GO:0050727=GO_REF:0000019, GO:0034698=GO_REF:0000019, GO:0070528=PMID:16611642, GO:0021766=GO_REF:0000019, GO:0007186=PMID:3419518, GO:0005887=PMID:3419518, GO:0001933=GO_REF:0000019, GO:0017046=GO_REF:0000019, GO:0001595=GO_REF:0000024, GO:0008584=GO_REF:0000019} P04201 Proto-oncogene Mas protein 20030904 {GO:0008284=IEA, GO:0004945=TAS, GO:0005886=IDA, GO:0008283=TAS, GO:0060732=IEA, GO:0007283=IEA, GO:0009653=TAS, GO:0071375=IEA, GO:0014823=IEA, GO:0042277=ISS, GO:0009986=IEA, GO:0007250=IEA, GO:0004930=IDA, GO:0042493=IEA, GO:0045740=IEA, GO:0050727=IEA, GO:0034698=IEA, GO:0070528=IMP, GO:0021766=IEA, GO:0007186=TAS, GO:0005887=TAS, GO:0001933=IEA, GO:0017046=IEA, GO:0001595=ISS, GO:0008584=IEA} G-protein coupled receptor signaling pathway, activation of NF-kappaB-inducing kinase activity, anatomical structure morphogenesis, cell proliferation, cellular response to peptide hormone stimulus, hippocampus development, male gonad development, negative regulation of protein phosphorylation, positive regulation of DNA replication, positive regulation of cell proliferation, positive regulation of inositol phosphate biosynthetic process, protein kinase C signaling cascade, regulation of inflammatory response, response to activity, response to drug, response to gonadotropin stimulus, spermatogenesis cell surface, integral to plasma membrane, plasma membrane G-protein coupled receptor activity, angiotensin receptor activity, angiotensin type II receptor activity, peptide binding, peptide hormone binding Human MASP1 Reactome UniProtKB {GO:0005515=PMID:10946292, GO:0006956=Reactome:REACT_8024, GO:0004252=PMID:11527969, GO:0045087=Reactome:REACT_6802, GO:0005509=PMID:18596036, GO:0006508=GO_REF:0000037, GO:0005576=Reactome:REACT_8002, GO:0008233=PMID:12538697, GO:0005615=PMID:11485744, GO:0042803=PMID:18596036, GO:0048306=PMID:18596036, GO:0001867=Reactome:REACT_7964} P48740 Mannan-binding lectin serine protease 1 protein 20050915 {GO:0005515=IPI, GO:0006956=TAS, GO:0004252=IDA, GO:0045087=TAS, GO:0005509=IDA, GO:0006508=IEA, GO:0005576=TAS, GO:0008233=IDA, GO:0005615=IDA, GO:0042803=IPI, GO:0048306=IPI, GO:0001867=TAS} complement activation, complement activation, lectin pathway, innate immune response, proteolysis extracellular region, extracellular space calcium ion binding, calcium-dependent protein binding, peptidase activity, protein binding, protein homodimerization activity, serine-type endopeptidase activity Human MASP2 Reactome UniProtKB {GO:0005515=PMID:10946292, GO:0006956=Reactome:REACT_8024, GO:0004252=PMID:9087411, GO:0045087=Reactome:REACT_6802, GO:0006958=GO_REF:0000037, GO:0005509=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0005576=Reactome:REACT_8002, GO:0008233=PMID:10946292, GO:0048306=PMID:12421953, GO:0001867=Reactome:REACT_7964} O00187 Mannan-binding lectin serine protease 2 protein 20050915 {GO:0005515=IPI, GO:0006956=TAS, GO:0004252=IDA, GO:0045087=TAS, GO:0006958=IEA, GO:0005509=IEA, GO:0006508=IEA, GO:0005576=TAS, GO:0008233=IDA, GO:0048306=IPI, GO:0001867=TAS} complement activation, complement activation, classical pathway, complement activation, lectin pathway, innate immune response, proteolysis extracellular region calcium ion binding, calcium-dependent protein binding, peptidase activity, protein binding, serine-type endopeptidase activity Human MAST1 IntAct UniProtKB {GO:0005515=PMID:20029029, GO:0005737=GO_REF:0000037, GO:0000287=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0004674=GO_REF:0000024, GO:0007010=GO_REF:0000024, GO:0006468=GO_REF:0000024, GO:0005856=GO_REF:0000039, GO:0005524=GO_REF:0000024, GO:0007243=GO_REF:0000024} Q9Y2H9 Microtubule-associated serine/threonine-protein kinase 1 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0000287=ISS, GO:0005886=IEA, GO:0004674=ISS, GO:0007010=ISS, GO:0006468=ISS, GO:0005856=IEA, GO:0005524=ISS, GO:0007243=ISS} cytoskeleton organization, intracellular protein kinase cascade, protein phosphorylation cytoplasm, cytoskeleton, plasma membrane ATP binding, magnesium ion binding, protein binding, protein serine/threonine kinase activity Human UniProtKB:P00533 MAST2 HPA UniProtKB {GO:0005515=PMID:12117771, GO:0008017=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0045075=GO_REF:0000024, GO:0000287=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0019902=PMID:10646847, GO:0004674=GO_REF:0000019, GO:0015630=GO_REF:0000019, GO:0048515=GO_REF:0000024, GO:0006468=GO_REF:0000024, GO:0005524=GO_REF:0000024} Q6P0Q8 Microtubule-associated serine/threonine-protein kinase 2 protein 20111111 {GO:0005515=IPI, GO:0008017=IEA, GO:0005737=IDA, GO:0045075=ISS, GO:0000287=ISS, GO:0005886=IEA, GO:0019902=IPI, GO:0004674=IEA, GO:0015630=IEA, GO:0048515=ISS, GO:0006468=ISS, GO:0005524=ISS} protein phosphorylation, regulation of interleukin-12 biosynthetic process, spermatid differentiation cytoplasm, microtubule cytoskeleton, plasma membrane ATP binding, magnesium ion binding, microtubule binding, phosphatase binding, protein binding, protein serine/threonine kinase activity Human MAST3 IntAct UniProtKB {GO:0005515=PMID:15951562, GO:0000287=GO_REF:0000002, GO:0004674=GO_REF:0000037, GO:0005524=GO_REF:0000037} O60307 Microtubule-associated serine/threonine-protein kinase 3 protein 20130415 {GO:0005515=IPI, GO:0000287=IEA, GO:0004674=IEA, GO:0005524=IEA} ATP binding, magnesium ion binding, protein binding, protein serine/threonine kinase activity Human UniProtKB:P60484 MAST4 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0000287=GO_REF:0000002, GO:0004674=GO_REF:0000037, GO:0005524=GO_REF:0000037} O15021 Microtubule-associated serine/threonine-protein kinase 4 protein 20130413 {GO:0005737=IEA, GO:0000287=IEA, GO:0004674=IEA, GO:0005524=IEA} cytoplasm ATP binding, magnesium ion binding, protein serine/threonine kinase activity Human UniProtKB-SubCell:SL-0086 MASTL Reactome UniProtKB {GO:0005813=PMID:20538976, GO:0005634=PMID:20538976, GO:0005524=GO_REF:0000037, GO:0032154=PMID:20538976, GO:0006974=GO_REF:0000024, GO:0034048=PMID:20538976, GO:0005737=GO_REF:0000037, GO:0007067=PMID:20538976, GO:0000088=Reactome:REACT_765, GO:0016301=PMID:20818157, GO:0004674=PMID:20538976, GO:0000086=PMID:20538976, GO:0000087=Reactome:REACT_910, GO:0051726=PMID:20818157, GO:0005654=Reactome:REACT_150326, GO:0000278=Reactome:REACT_152, GO:0051721=GO_REF:0000024, GO:0051301=GO_REF:0000037} Q96GX5 Serine/threonine-protein kinase greatwall protein 20121003 {GO:0005813=IDA, GO:0005634=IDA, GO:0005524=IEA, GO:0032154=IDA, GO:0006974=ISS, GO:0034048=IMP, GO:0005737=IEA, GO:0007067=IMP, GO:0000088=TAS, GO:0016301=IDA, GO:0004674=IDA, GO:0000086=IMP, GO:0000087=TAS, GO:0051726=IMP, GO:0005654=TAS, GO:0000278=TAS, GO:0051721=ISS, GO:0051301=IEA} G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, cell division, mitosis, mitotic cell cycle, mitotic prophase, negative regulation of protein phosphatase type 2A activity, regulation of cell cycle, response to DNA damage stimulus centrosome, cleavage furrow, cytoplasm, nucleoplasm, nucleus ATP binding, kinase activity, protein phosphatase 2A binding, protein serine/threonine kinase activity Human MAT1A Reactome UniProtKB {GO:0034641=Reactome:REACT_13, GO:0006520=PMID:1772450, GO:0006805=Reactome:REACT_13433, GO:0000096=Reactome:REACT_115639, GO:0006556=GO_REF:0000041, GO:0044281=Reactome:REACT_111217, GO:0032259=Reactome:REACT_6946, GO:0006730=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0004478=GO_REF:0000003, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_6819} Q00266 S-adenosylmethionine synthase isoform type-1 protein 20080604 {GO:0034641=TAS, GO:0006520=TAS, GO:0006805=TAS, GO:0000096=TAS, GO:0006556=IEA, GO:0044281=TAS, GO:0032259=TAS, GO:0006730=IEA, GO:0005524=IEA, GO:0004478=IEA, GO:0046872=IEA, GO:0005829=TAS} S-adenosylmethionine biosynthetic process, cellular amino acid metabolic process, cellular nitrogen compound metabolic process, methylation, one-carbon metabolic process, small molecule metabolic process, sulfur amino acid metabolic process, xenobiotic metabolic process cytosol ATP binding, metal ion binding, methionine adenosyltransferase activity Human MAT2A Reactome UniProtKB {GO:0034641=Reactome:REACT_13, GO:0006805=Reactome:REACT_13433, GO:0000096=Reactome:REACT_115639, GO:0006556=GO_REF:0000041, GO:0044281=Reactome:REACT_111217, GO:0032259=Reactome:REACT_6946, GO:0004478=GO_REF:0000003, GO:0006730=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_6819} P31153 S-adenosylmethionine synthase isoform type-2 protein 20130213 {GO:0034641=TAS, GO:0006805=TAS, GO:0000096=TAS, GO:0006556=IEA, GO:0044281=TAS, GO:0032259=TAS, GO:0004478=IEA, GO:0006730=IEA, GO:0005524=IEA, GO:0046872=IEA, GO:0005829=TAS} S-adenosylmethionine biosynthetic process, cellular nitrogen compound metabolic process, methylation, one-carbon metabolic process, small molecule metabolic process, sulfur amino acid metabolic process, xenobiotic metabolic process cytosol ATP binding, metal ion binding, methionine adenosyltransferase activity Human MAT2B LIFEdb UniProtKB {GO:0005515=PMID:10644686, GO:0050662=GO_REF:0000002, GO:0006805=Reactome:REACT_13433, GO:0005634=GO_REF:0000054, GO:0008831=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0032259=Reactome:REACT_6946, GO:0005829=Reactome:REACT_6819, GO:0045226=GO_REF:0000002, GO:0005739=GO_REF:0000019, GO:0005622=PMID:10644686, GO:0034641=Reactome:REACT_13, GO:0000096=Reactome:REACT_115639, GO:0048270=PMID:10644686, GO:0006556=PMID:10644686, GO:0006730=GO_REF:0000037, GO:0044237=GO_REF:0000002, GO:0048269=PMID:10644686} Q9NZL9 Methionine adenosyltransferase 2 subunit beta protein 20100607 {GO:0005515=IPI, GO:0050662=IEA, GO:0006805=TAS, GO:0005634=IDA, GO:0008831=IEA, GO:0044281=TAS, GO:0003824=IEA, GO:0032259=TAS, GO:0005829=TAS, GO:0045226=IEA, GO:0005739=IEA, GO:0005622=IC, GO:0034641=TAS, GO:0000096=TAS, GO:0048270=IDA, GO:0006556=IDA, GO:0006730=IEA, GO:0044237=IEA, GO:0048269=IDA} S-adenosylmethionine biosynthetic process, cellular metabolic process, cellular nitrogen compound metabolic process, extracellular polysaccharide biosynthetic process, methylation, one-carbon metabolic process, small molecule metabolic process, sulfur amino acid metabolic process, xenobiotic metabolic process cytosol, intracellular, methionine adenosyltransferase complex, mitochondrion, nucleus catalytic activity, coenzyme binding, dTDP-4-dehydrorhamnose reductase activity, methionine adenosyltransferase regulator activity, protein binding Human MATK HPA UniProtKB {GO:0005515=PMID:22939624, GO:0008284=PMID:8999872, GO:0008283=PMID:8288563, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_115602, GO:0005737=GO_REF:0000052, GO:0016020=GO_REF:0000039, GO:0006468=PMID:7530249, GO:0007498=PMID:8288563, GO:0004713=PMID:7530249, GO:0004715=GO_REF:0000003} P42679 Megakaryocyte-associated tyrosine-protein kinase protein 20100326 {GO:0005515=IPI, GO:0008284=TAS, GO:0008283=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0005524=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0016020=IEA, GO:0006468=TAS, GO:0007498=TAS, GO:0004713=TAS, GO:0004715=IEA} cell proliferation, mesoderm development, positive regulation of cell proliferation, protein phosphorylation cytoplasm, cytosol, membrane, nucleolus, nucleus ATP binding, non-membrane spanning protein tyrosine kinase activity, protein binding, protein tyrosine kinase activity Human MATN1 PINC UniProtKB {GO:0005515=PMID:15075323, GO:0030500=GO_REF:0000019, GO:0006461=PMID:9083061, GO:0005578=GO_REF:0000039, GO:0003429=GO_REF:0000019, GO:0005201=PMID:9083061} P21941 Cartilage matrix protein protein 20030904 {GO:0005515=IPI, GO:0030500=IEA, GO:0006461=TAS, GO:0005578=IEA, GO:0003429=IEA, GO:0005201=TAS} growth plate cartilage chondrocyte morphogenesis, protein complex assembly, regulation of bone mineralization proteinaceous extracellular matrix extracellular matrix structural constituent, protein binding Human MATN2 BHF-UCL UniProtKB {GO:0031012=PMID:22261194, GO:0005515=PMID:21078624, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0031104=GO_REF:0000019, GO:0008347=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0005578=PMID:11124542, GO:0001764=GO_REF:0000019, GO:0048678=GO_REF:0000019, GO:0005604=GO_REF:0000019} O00339 Matrilin-2 protein 20120228 {GO:0031012=ISS, GO:0005515=IPI, GO:0008150=ND, GO:0003674=ND, GO:0031104=IEA, GO:0008347=IEA, GO:0007411=IEA, GO:0005509=IEA, GO:0005578=NAS, GO:0001764=IEA, GO:0048678=IEA, GO:0005604=IEA} axon guidance, biological_process, dendrite regeneration, glial cell migration, neuron migration, response to axon injury basement membrane, extracellular matrix, proteinaceous extracellular matrix calcium ion binding, molecular_function, protein binding colocalizes_with Human UniProtKB:F1S0M0 MATN3 UniProtKB UniProtKB {GO:0005515=PMID:15075323, GO:0001501=PMID:9350998, GO:0005509=GO_REF:0000002, GO:0005578=GO_REF:0000019, GO:0005201=PMID:9350998} O15232 Matrilin-3 protein 20090909 {GO:0005515=IPI, GO:0001501=TAS, GO:0005509=IEA, GO:0005578=IEA, GO:0005201=TAS} skeletal system development proteinaceous extracellular matrix calcium ion binding, extracellular matrix structural constituent, protein binding Human UniProtKB:P49747 MATN4 UniProtKB UniProtKB {GO:0005515=PMID:15075323, GO:0005509=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0048678=GO_REF:0000019} O95460 Matrilin-4 protein 20090909 {GO:0005515=IPI, GO:0005509=IEA, GO:0005576=IEA, GO:0048678=IEA} response to axon injury extracellular region calcium ion binding, protein binding Human UniProtKB:P49747 MATR3 HPA UniProtKB {GO:0005515=PMID:20195357, GO:0000166=GO_REF:0000002, GO:0005198=PMID:2033075, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005637=PMID:2033075, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0016363=GO_REF:0000039} P43243 Matrin-3 protein 20110516 {GO:0005515=IPI, GO:0000166=IEA, GO:0005198=TAS, GO:0003723=IEA, GO:0005730=IDA, GO:0005637=TAS, GO:0005634=IDA, GO:0008270=IEA, GO:0003676=IEA, GO:0016363=IEA} nuclear inner membrane, nuclear matrix, nucleolus, nucleus RNA binding, nucleic acid binding, nucleotide binding, protein binding, structural molecule activity, zinc ion binding NOT Human MAU2 Reactome UniProtKB {GO:0005515=PMID:16682347, GO:0000910=Reactome:REACT_1932, GO:0047485=PMID:16802858, GO:0000087=Reactome:REACT_910, GO:0034088=PMID:16802858, GO:0005634=PMID:16802858, GO:0005654=Reactome:REACT_150390, GO:0032116=PMID:16802858, GO:0000278=Reactome:REACT_152, GO:0000785=PMID:16682347} Q9Y6X3 MAU2 chromatid cohesion factor homolog protein 20111003 {GO:0005515=IPI, GO:0000910=TAS, GO:0047485=IPI, GO:0000087=TAS, GO:0034088=IMP, GO:0005634=IDA, GO:0005654=TAS, GO:0032116=IMP, GO:0000278=TAS, GO:0000785=IDA} M phase of mitotic cell cycle, cytokinesis, maintenance of mitotic sister chromatid cohesion, mitotic cell cycle SMC loading complex, chromatin, nucleoplasm, nucleus protein N-terminus binding, protein binding Human MAVS BHF-UCL UniProtKB {GO:0005515=PMID:16127453, GO:0033160=PMID:18818105, GO:1900063=PMID:20451243, GO:0071651=PMID:16127453, GO:0005741=PMID:18818105, GO:0002218=PMID:18818105, GO:0042993=PMID:18818105, GO:0032757=PMID:16127453, GO:0051607=PMID:20451243, GO:0051091=PMID:16127453, GO:0045944=PMID:18818105, GO:0004871=PMID:20451243, GO:0043123=PMID:12761501, GO:0032480=Reactome:REACT_25271, GO:0042742=PMID:19631370, GO:0045071=PMID:20451243, GO:0050700=PMID:16127453, GO:0032728=PMID:16127453, GO:0032760=PMID:16127453, GO:0019901=PMID:16127453, GO:0032727=PMID:16127453, GO:0071660=PMID:16127453, GO:0071360=PMID:16127453, GO:0007165=PMID:20451243, GO:0045087=Reactome:REACT_6802, GO:0019048=GO_REF:0000037, GO:0002230=PMID:16127453, GO:0001934=PMID:16127453, GO:0060340=PMID:16127453, GO:0016021=GO_REF:0000037} Q7Z434 Mitochondrial antiviral-signaling protein protein 20110310 {GO:0005515=IPI, GO:0033160=IDA, GO:1900063=IMP, GO:0071651=IDA, GO:0005741=IDA, GO:0002218=IMP, GO:0042993=IDA, GO:0032757=IDA, GO:0051607=IDA, GO:0051091=IDA, GO:0045944=IDA, GO:0004871=IMP, GO:0043123=IMP, GO:0032480=TAS, GO:0042742=IMP, GO:0045071=IDA, GO:0050700=IPI, GO:0032728=IDA, GO:0032760=IDA, GO:0019901=IPI, GO:0032727=IDA, GO:0071660=IDA, GO:0071360=IMP, GO:0007165=IMP, GO:0045087=TAS, GO:0019048=IEA, GO:0002230=IDA, GO:0001934=IDA, GO:0060340=IDA, GO:0016021=IEA} activation of innate immune response, cellular response to exogenous dsRNA, defense response to bacterium, defense response to virus, innate immune response, negative regulation of type I interferon production, negative regulation of viral genome replication, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of IP-10 production, positive regulation of chemokine (C-C motif) ligand 5 production, positive regulation of defense response to virus by host, positive regulation of interferon-alpha production, positive regulation of interferon-beta production, positive regulation of interleukin-8 production, positive regulation of protein import into nucleus, translocation, positive regulation of protein phosphorylation, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription factor import into nucleus, positive regulation of transcription from RNA polymerase II promoter, positive regulation of tumor necrosis factor production, positive regulation of type I interferon-mediated signaling pathway, regulation of peroxisome organization, signal transduction, virus-host interaction integral to membrane, mitochondrial outer membrane CARD domain binding, protein binding, protein kinase binding, signal transducer activity Human MAX InterPro UniProtKB {GO:0003712=PMID:8425218, GO:0005515=PMID:20195357, GO:0032868=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0006366=PMID:8425218, GO:0060041=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0003713=PMID:2006410, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0051402=GO_REF:0000019, GO:0048678=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0006461=GO_REF:0000019, GO:0071339=PMID:15960975, GO:0016605=GO_REF:0000019, GO:0071375=GO_REF:0000019, GO:0010629=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0009267=GO_REF:0000019} Q6V3B1 MAX protein protein 20130413 {GO:0003712=TAS, GO:0005515=IPI, GO:0032868=IEA, GO:0003700=IEA, GO:0006366=TAS, GO:0060041=IEA, GO:0046982=IEA, GO:0003713=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0051402=IEA, GO:0048678=IEA, GO:0032403=IEA, GO:0030425=IEA, GO:0042803=IEA, GO:0043565=IEA, GO:0005737=IDA, GO:0006461=IEA, GO:0071339=IDA, GO:0016605=IEA, GO:0071375=IEA, GO:0010629=IEA, GO:0046983=IEA, GO:0009267=IEA} cellular response to peptide hormone stimulus, cellular response to starvation, negative regulation of gene expression, neuron apoptotic process, protein complex assembly, response to axon injury, response to insulin stimulus, retina development in camera-type eye, transcription from RNA polymerase II promoter MLL1 complex, PML body, cytoplasm, dendrite, nucleolus, nucleus protein binding, protein complex binding, protein dimerization activity, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, transcription cofactor activity Human InterPro:IPR011598 MAZ IntAct UniProtKB {GO:0005515=PMID:11527412, GO:0006355=GO_REF:0000037, GO:0005737=GO_REF:0000019, GO:0003723=GO_REF:0000037, GO:0045944=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0000981=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000019} P56270 Myc-associated zinc finger protein protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0005737=IEA, GO:0003723=IEA, GO:0045944=IEA, GO:0003682=IEA, GO:0000981=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA} positive regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent cytoplasm, nucleus DNA binding, RNA binding, chromatin binding, nucleic acid binding, protein binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, zinc ion binding Human UniProtKB:Q91562 MB ENSEMBL UniProtKB {GO:0007507=GO_REF:0000019, GO:0042542=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0019825=GO_REF:0000019, GO:0005506=GO_REF:0000002, GO:0050873=GO_REF:0000019, GO:0005344=GO_REF:0000038, GO:0031444=GO_REF:0000019, GO:0009725=GO_REF:0000019, GO:0043353=GO_REF:0000019, GO:0015671=GO_REF:0000019, GO:0020037=GO_REF:0000002} Q8WVH6 MB protein protein 20130413 {GO:0007507=IEA, GO:0042542=IEA, GO:0001666=IEA, GO:0019825=IEA, GO:0005506=IEA, GO:0050873=IEA, GO:0005344=IEA, GO:0031444=IEA, GO:0009725=IEA, GO:0043353=IEA, GO:0015671=IEA, GO:0020037=IEA} brown fat cell differentiation, enucleate erythrocyte differentiation, heart development, oxygen transport, response to hormone stimulus, response to hydrogen peroxide, response to hypoxia, slow-twitch skeletal muscle fiber contraction heme binding, iron ion binding, oxygen binding, oxygen transporter activity Human Ensembl:ENSMUSP00000125995 MB21D1 UniProtKB UniProtKB {GO:0071360=PMID:23258413, GO:0051607=GO_REF:0000037, GO:0002230=PMID:23258413, GO:0045087=GO_REF:0000037, GO:0002218=PMID:23258413, GO:0009190=PMID:23258413, GO:0003677=PMID:23258413, GO:0046872=GO_REF:0000037, GO:0005829=PMID:23258413, GO:0061501=PMID:23258413} Q8N884 Cyclic GMP-AMP synthase protein 20130118 {GO:0071360=IDA, GO:0051607=IEA, GO:0002230=IMP, GO:0045087=IEA, GO:0002218=IMP, GO:0009190=IDA, GO:0003677=IDA, GO:0046872=IEA, GO:0005829=IDA, GO:0061501=IDA} activation of innate immune response, cellular response to exogenous dsRNA, cyclic nucleotide biosynthetic process, defense response to virus, innate immune response, positive regulation of defense response to virus by host cytosol DNA binding, cyclic-GMP-AMP synthase activity, metal ion binding Human MB21D2 null null {} null null null null {} null null null MBD1 IntAct UniProtKB {GO:0000792=GO_REF:0000019, GO:0005515=PMID:23275563, GO:0008327=PMID:10454587, GO:0003700=PMID:10866667, GO:0006366=PMID:9774669, GO:0003714=PMID:10866667, GO:0005634=PMID:10454587, GO:0003677=PMID:9774669, GO:0016363=GO_REF:0000024, GO:0005737=GO_REF:0000019, GO:0016607=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0045892=PMID:10454587} Q9UIS9 Methyl-CpG-binding domain protein 1 protein 20130415 {GO:0000792=IEA, GO:0005515=IPI, GO:0008327=NAS, GO:0003700=TAS, GO:0006366=TAS, GO:0003714=TAS, GO:0005634=NAS, GO:0003677=TAS, GO:0016363=ISS, GO:0005737=IEA, GO:0016607=ISS, GO:0008270=IEA, GO:0045892=NAS} negative regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter cytoplasm, heterochromatin, nuclear matrix, nuclear speck, nucleus DNA binding, methyl-CpG binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity, zinc ion binding Human UniProtKB:P42858 MBD2 PINC UniProtKB {GO:0005515=PMID:12183469, GO:0000792=GO_REF:0000019, GO:0042711=GO_REF:0000019, GO:0008327=PMID:21029866, GO:0019904=PMID:11984006, GO:0030177=GO_REF:0000019, GO:0005634=PMID:11553631, GO:0000122=GO_REF:0000019, GO:0003729=GO_REF:0000019, GO:0003677=GO_REF:0000002, GO:0043623=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0005737=GO_REF:0000019, GO:0000118=GO_REF:0000019, GO:0035197=GO_REF:0000019, GO:0003696=PMID:9774669, GO:0003682=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0070742=PMID:11553631, GO:0045892=PMID:10441743} Q9UBB5 Methyl-CpG-binding domain protein 2 protein 20050308 {GO:0005515=IPI, GO:0000792=IEA, GO:0042711=IEA, GO:0008327=IDA, GO:0019904=IPI, GO:0030177=IEA, GO:0005634=IDA, GO:0000122=IEA, GO:0003729=IEA, GO:0003677=IEA, GO:0043623=IEA, GO:0006351=IEA, GO:0005737=IEA, GO:0000118=IEA, GO:0035197=IEA, GO:0003696=TAS, GO:0003682=IEA, GO:0042127=IEA, GO:0070742=IPI, GO:0045892=NAS} cellular protein complex assembly, maternal behavior, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of Wnt receptor signaling pathway, regulation of cell proliferation, transcription, DNA-dependent cytoplasm, heterochromatin, histone deacetylase complex, nucleus C2H2 zinc finger domain binding, DNA binding, chromatin binding, mRNA binding, methyl-CpG binding, protein binding, protein domain specific binding, satellite DNA binding, siRNA binding Human MBD3 BHF-UCL UniProtKB {GO:0000792=GO_REF:0000019, GO:0005515=PMID:20676135, GO:0016573=GO_REF:0000019, GO:0006346=GO_REF:0000019, GO:0005634=GO_REF:0000002, GO:0000122=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0005737=GO_REF:0000019, GO:0016581=PMID:17827154, GO:0003682=GO_REF:0000019, GO:0009888=GO_REF:0000019} O95983 Methyl-CpG-binding domain protein 3 protein 20090625 {GO:0000792=IEA, GO:0005515=IPI, GO:0016573=IEA, GO:0006346=IEA, GO:0005634=IEA, GO:0000122=IEA, GO:0003677=IEA, GO:0001701=IEA, GO:0006351=IEA, GO:0005737=IEA, GO:0016581=NAS, GO:0003682=IEA, GO:0009888=IEA} histone acetylation, in utero embryonic development, methylation-dependent chromatin silencing, negative regulation of transcription from RNA polymerase II promoter, tissue development, transcription, DNA-dependent NuRD complex, cytoplasm, heterochromatin, nucleus DNA binding, chromatin binding, protein binding Human MBD3L1 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q8WWY6 Methyl-CpG-binding domain protein 3-like 1 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus Human UniProtKB-SubCell:SL-0191 MBD3L2 null null {} null null null null {} null null null MBD4 InterPro UniProtKB {GO:0005515=PMID:12702765, GO:0009314=GO_REF:0000019, GO:0008630=GO_REF:0000019, GO:0031572=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0004520=PMID:10097147, GO:0005634=GO_REF:0000052, GO:0003824=GO_REF:0000002, GO:0003677=GO_REF:0000002, GO:0005737=GO_REF:0000019, GO:0006281=Reactome:REACT_216, GO:0003696=PMID:9774669, GO:0006284=GO_REF:0000002, GO:0045008=Reactome:REACT_2156, GO:0006285=Reactome:REACT_804, GO:0005654=Reactome:REACT_1057, GO:0008263=PMID:14614141, GO:0000785=GO_REF:0000019} Q2MD36 Methyl-CpG-binding domain protein 4 protein 20130413 {GO:0005515=IPI, GO:0009314=IEA, GO:0008630=IEA, GO:0031572=IEA, GO:0005730=IDA, GO:0004520=TAS, GO:0005634=IDA, GO:0003824=IEA, GO:0003677=IEA, GO:0005737=IEA, GO:0006281=TAS, GO:0003696=TAS, GO:0006284=IEA, GO:0045008=TAS, GO:0006285=TAS, GO:0005654=TAS, GO:0008263=IDA, GO:0000785=IEA} DNA repair, G2 DNA damage checkpoint, base-excision repair, base-excision repair, AP site formation, depyrimidination, intrinsic apoptotic signaling pathway in response to DNA damage, response to radiation chromatin, cytoplasm, nucleolus, nucleoplasm, nucleus DNA binding, catalytic activity, endodeoxyribonuclease activity, protein binding, pyrimidine-specific mismatch base pair DNA N-glycosylase activity, satellite DNA binding Human InterPro:IPR003265 MBD5 UniProtKB UniProtKB {GO:0005694=GO_REF:0000039, GO:0003682=PMID:20700456, GO:0005634=GO_REF:0000039, GO:0003677=PMID:20700456} Q9P267 Methyl-CpG-binding domain protein 5 protein 20110221 {GO:0005694=IEA, GO:0003682=IDA, GO:0005634=IEA, GO:0003677=IDA} chromosome, nucleus DNA binding, chromatin binding NOT Human MBD6 HPA UniProtKB {GO:0005694=GO_REF:0000039, GO:0003682=PMID:20700456, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=PMID:20700456} Q96DN6 Methyl-CpG-binding domain protein 6 protein 20111111 {GO:0005694=IEA, GO:0003682=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IDA} chromosome, nucleolus, nucleus DNA binding, chromatin binding NOT Human MBIP HPA UniProtKB {GO:0005515=PMID:19060904, GO:0000173=PMID:10801814, GO:0005737=GO_REF:0000052, GO:0043966=PMID:18838386, GO:0005730=GO_REF:0000052, GO:0005671=PMID:18838386, GO:0004860=PMID:10801814, GO:0042802=PMID:19060904} Q9NS73 MAP3K12-binding inhibitory protein 1 protein 20101115 {GO:0005515=IPI, GO:0000173=TAS, GO:0005737=IDA, GO:0043966=IDA, GO:0005730=IDA, GO:0005671=IDA, GO:0004860=TAS, GO:0042802=IPI} histone H3 acetylation, inactivation of MAPK activity involved in osmosensory signaling pathway Ada2/Gcn5/Ada3 transcription activator complex, cytoplasm, nucleolus identical protein binding, protein binding, protein kinase inhibitor activity Human MBL2 BHF-UCL UniProtKB {GO:0005515=PMID:11485744, GO:0005581=GO_REF:0000037, GO:0051873=GO_REF:0000019, GO:0043499=PMID:2477488, GO:0050830=PMID:15148336, GO:0005102=PMID:11549596, GO:0005576=Reactome:REACT_8002, GO:0006953=PMID:2477488, GO:0005615=GO_REF:0000019, GO:0005537=PMID:2477488, GO:0001867=Reactome:REACT_7964, GO:0051635=PMID:2477488, GO:0006956=Reactome:REACT_8024, GO:0050766=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0006958=GO_REF:0000037, GO:0044130=PMID:15148336, GO:0006979=PMID:11549596, GO:0008228=PMID:2477488, GO:0048306=PMID:12421953} P11226 Mannose-binding protein C protein 20080707 {GO:0005515=IPI, GO:0005581=IEA, GO:0051873=IEA, GO:0043499=TAS, GO:0050830=IDA, GO:0005102=IPI, GO:0005576=TAS, GO:0006953=TAS, GO:0005615=IEA, GO:0005537=TAS, GO:0001867=TAS, GO:0051635=TAS, GO:0006956=TAS, GO:0050766=IEA, GO:0045087=TAS, GO:0006958=IEA, GO:0044130=IDA, GO:0006979=NAS, GO:0008228=TAS, GO:0048306=IPI} acute-phase response, complement activation, complement activation, classical pathway, complement activation, lectin pathway, defense response to Gram-positive bacterium, innate immune response, killing by host of symbiont cells, negative regulation of growth of symbiont in host, opsonization, positive regulation of phagocytosis, response to oxidative stress collagen, extracellular region, extracellular space bacterial cell surface binding, calcium-dependent protein binding, eukaryotic cell surface binding, mannose binding, protein binding, receptor binding Human MBLAC2 UniProtKB UniProtKB {GO:0016787=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q68D91 Metallo-beta-lactamase domain-containing protein 2 protein 20130413 {GO:0016787=IEA, GO:0046872=IEA} hydrolase activity, metal ion binding Human UniProtKB-KW:KW-0479 MBNL1 MGI UniProtKB {GO:0008380=PMID:18335541, GO:0005515=PMID:18335541, GO:0003725=PMID:10970838, GO:0010494=PMID:18335541, GO:0003723=PMID:16946708, GO:0006376=GO_REF:0000019, GO:0005634=PMID:16717059, GO:0030326=GO_REF:0000024, GO:0003676=GO_REF:0000002, GO:0001701=GO_REF:0000024, GO:0007399=GO_REF:0000024, GO:0005737=PMID:10970838, GO:0000381=GO_REF:0000019, GO:0007519=GO_REF:0000019, GO:0000380=GO_REF:0000019, GO:0043484=PMID:16946708, GO:0008270=GO_REF:0000002, GO:0045445=GO_REF:0000024} Q9NR56 Muscleblind-like protein 1 protein 20061016 {GO:0008380=IDA, GO:0005515=IPI, GO:0003725=IDA, GO:0010494=IDA, GO:0003723=IDA, GO:0006376=IEA, GO:0005634=IDA, GO:0030326=ISS, GO:0003676=IEA, GO:0001701=ISS, GO:0007399=ISS, GO:0005737=IDA, GO:0000381=IEA, GO:0007519=IEA, GO:0000380=IEA, GO:0043484=IDA, GO:0008270=IEA, GO:0045445=ISS} RNA splicing, alternative mRNA splicing, via spliceosome, embryonic limb morphogenesis, in utero embryonic development, mRNA splice site selection, myoblast differentiation, nervous system development, regulation of RNA splicing, regulation of alternative mRNA splicing, via spliceosome, skeletal muscle tissue development cytoplasm, cytoplasmic stress granule, nucleus RNA binding, double-stranded RNA binding, nucleic acid binding, protein binding, zinc ion binding Human MBNL2 UniProtKB UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0000381=GO_REF:0000019, GO:0003723=GO_REF:0000037, GO:0043484=PMID:16946708, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q5VZF2 Muscleblind-like protein 2 protein 20100115 {GO:0008380=IEA, GO:0006397=IEA, GO:0005737=IEA, GO:0000381=IEA, GO:0003723=IEA, GO:0043484=IDA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA} RNA splicing, mRNA processing, regulation of RNA splicing, regulation of alternative mRNA splicing, via spliceosome cytoplasm, nucleus RNA binding, nucleic acid binding, zinc ion binding Human MBNL3 HPA UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0005794=GO_REF:0000052, GO:0043484=PMID:15257297, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0045662=GO_REF:0000019, GO:0043231=GO_REF:0000052} Q9NUK0 Muscleblind-like protein 3 protein 20101115 {GO:0008380=IEA, GO:0006397=IEA, GO:0005794=IDA, GO:0043484=IDA, GO:0005634=IEA, GO:0007275=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0045662=IEA, GO:0043231=IDA} RNA splicing, mRNA processing, multicellular organismal development, negative regulation of myoblast differentiation, regulation of RNA splicing Golgi apparatus, intracellular membrane-bounded organelle, nucleus nucleic acid binding, zinc ion binding Human MBOAT7 IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0016747=GO_REF:0000003, GO:0036149=Reactome:REACT_120722, GO:0021591=GO_REF:0000019, GO:0005789=Reactome:REACT_121046, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0046474=Reactome:REACT_121401} Q96N66 Lysophospholipid acyltransferase 7 protein 20130415 {GO:0005515=IPI, GO:0016747=IEA, GO:0036149=TAS, GO:0021591=IEA, GO:0005789=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0006644=TAS, GO:0046474=TAS} glycerophospholipid biosynthetic process, phosphatidylinositol acyl-chain remodeling, phospholipid metabolic process, small molecule metabolic process, ventricular system development endoplasmic reticulum membrane, integral to membrane protein binding, transferase activity, transferring acyl groups other than amino-acyl groups Human UniProtKB:Q8VCW4 MBP PINC UniProtKB {GO:0005886=GO_REF:0000037, GO:0042552=GO_REF:0000019, GO:0007268=PMID:2434243, GO:0009636=GO_REF:0000019, GO:0008366=PMID:2434243, GO:0002020=GO_REF:0000019, GO:0007417=PMID:2434243, GO:0071944=GO_REF:0000019, GO:0033269=GO_REF:0000019, GO:0006955=PMID:7504278, GO:0043218=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0061024=GO_REF:0000019, GO:0019911=GO_REF:0000002, GO:0050771=GO_REF:0000019} P02686 Myelin basic protein protein 20030904 {GO:0005886=IEA, GO:0042552=IEA, GO:0007268=TAS, GO:0009636=IEA, GO:0008366=TAS, GO:0002020=IEA, GO:0007417=TAS, GO:0071944=IEA, GO:0033269=IEA, GO:0006955=TAS, GO:0043218=IEA, GO:0043025=IEA, GO:0061024=IEA, GO:0019911=IEA, GO:0050771=IEA} axon ensheathment, central nervous system development, immune response, membrane organization, myelination, negative regulation of axonogenesis, response to toxic substance, synaptic transmission cell periphery, compact myelin, internode region of axon, neuronal cell body, plasma membrane protease binding, structural constituent of myelin sheath Human MBTD1 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q05BQ5 MBT domain-containing protein 1 protein 20130413 {GO:0006355=IEA, GO:0008270=IEA, GO:0005634=IEA, GO:0006351=IEA, GO:0016568=IEA} chromatin modification, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus zinc ion binding Human UniProtKB-SubCell:SL-0191 MBTPS1 Reactome UniProtKB {GO:0006629=GO_REF:0000033, GO:0005794=GO_REF:0000033, GO:0004252=GO_REF:0000033, GO:0005795=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0042990=GO_REF:0000019, GO:0030968=Reactome:REACT_18356, GO:0000139=Reactome:REACT_147792, GO:0006508=GO_REF:0000033, GO:0005789=GO_REF:0000039, GO:0005788=PMID:9809072, GO:0016021=GO_REF:0000037, GO:0006987=Reactome:REACT_18348, GO:0044267=Reactome:REACT_17015, GO:0008203=GO_REF:0000037} Q14703 Membrane-bound transcription factor site-1 protease protein 20130301 {GO:0006629=IBA, GO:0005794=IBA, GO:0004252=IBA, GO:0005795=IEA, GO:0044281=TAS, GO:0042990=IEA, GO:0030968=TAS, GO:0000139=TAS, GO:0006508=IBA, GO:0005789=IEA, GO:0005788=TAS, GO:0016021=IEA, GO:0006987=TAS, GO:0044267=TAS, GO:0008203=IEA} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, cholesterol metabolic process, endoplasmic reticulum unfolded protein response, lipid metabolic process, proteolysis, regulation of transcription factor import into nucleus, small molecule metabolic process Golgi apparatus, Golgi membrane, Golgi stack, endoplasmic reticulum lumen, endoplasmic reticulum membrane, integral to membrane serine-type endopeptidase activity Human MBTPS2 Reactome UniProtKB {GO:0005737=PMID:19361614, GO:0000139=Reactome:REACT_147876, GO:0016020=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0006987=Reactome:REACT_18348, GO:0004222=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0046872=GO_REF:0000037, GO:0030968=Reactome:REACT_18356, GO:0008203=GO_REF:0000037} O43462 Membrane-bound transcription factor site-2 protease protein 20130301 {GO:0005737=IDA, GO:0000139=TAS, GO:0016020=IEA, GO:0006508=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0006987=TAS, GO:0004222=IEA, GO:0044267=TAS, GO:0046872=IEA, GO:0030968=TAS, GO:0008203=IEA} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, cholesterol metabolic process, endoplasmic reticulum unfolded protein response, proteolysis, small molecule metabolic process Golgi membrane, cytoplasm, integral to membrane, membrane metal ion binding, metalloendopeptidase activity Human MC1R HPA UniProtKB {GO:0005515=PMID:19329486, GO:0051897=PMID:18292087, GO:0009650=PMID:7581459, GO:0005886=GO_REF:0000052, GO:0030819=PMID:19329486, GO:0032720=PMID:10233018, GO:0008528=PMID:18292087, GO:0007275=PMID:7581459, GO:0010739=PMID:18292087, GO:0007243=PMID:18292087, GO:0019233=GO_REF:0000019, GO:0004977=PMID:9571181, GO:0005737=GO_REF:0000052, GO:0090037=PMID:18292087, GO:0042438=GO_REF:0000019, GO:0005887=PMID:9571181, GO:0007187=PMID:9571181, GO:0045944=PMID:18292087, GO:0004980=PMID:19743876, GO:0015630=GO_REF:0000052, GO:0070914=PMID:18292087, GO:0043473=PMID:18292087, GO:0016021=GO_REF:0000038, GO:0031625=PMID:19737927} Q01726 Melanocyte-stimulating hormone receptor protein 20120912 {GO:0005515=IPI, GO:0051897=ISS, GO:0009650=TAS, GO:0005886=IDA, GO:0030819=IDA, GO:0032720=IMP, GO:0008528=TAS, GO:0007275=TAS, GO:0010739=ISS, GO:0007243=ISS, GO:0019233=IEA, GO:0004977=TAS, GO:0005737=IDA, GO:0090037=ISS, GO:0042438=IEA, GO:0005887=TAS, GO:0007187=TAS, GO:0045944=ISS, GO:0004980=IPI, GO:0015630=IDA, GO:0070914=IDA, GO:0043473=TAS, GO:0016021=IEA, GO:0031625=IPI} G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, UV protection, UV-damage excision repair, intracellular protein kinase cascade, melanin biosynthetic process, multicellular organismal development, negative regulation of tumor necrosis factor production, pigmentation, positive regulation of cAMP biosynthetic process, positive regulation of protein kinase A signaling cascade, positive regulation of protein kinase B signaling cascade, positive regulation of protein kinase C signaling cascade, positive regulation of transcription from RNA polymerase II promoter, sensory perception of pain cytoplasm, integral to membrane, integral to plasma membrane, microtubule cytoskeleton, plasma membrane G-protein coupled peptide receptor activity, melanocortin receptor activity, melanocyte-stimulating hormone receptor activity, protein binding, ubiquitin protein ligase binding Human MC2R BHF-UCL UniProtKB {GO:0005515=PMID:19329486, GO:0005886=Reactome:REACT_22268, GO:0007186=PMID:1325670, GO:0007187=PMID:9175632, GO:0005887=PMID:9175632, GO:0030819=PMID:19329486, GO:0004978=GO_REF:0000002, GO:0004977=PMID:1325670} Q01718 Adrenocorticotropic hormone receptor protein 20100130 {GO:0005515=IPI, GO:0005886=TAS, GO:0007186=TAS, GO:0007187=TAS, GO:0005887=TAS, GO:0030819=IDA, GO:0004978=IEA, GO:0004977=TAS} G-protein coupled receptor signaling pathway, G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, positive regulation of cAMP biosynthetic process integral to plasma membrane, plasma membrane corticotropin receptor activity, melanocortin receptor activity, protein binding Human MC3R BHF-UCL UniProtKB {GO:0005515=PMID:19329486, GO:0005886=Reactome:REACT_22268, GO:0030819=PMID:19329486, GO:0007200=PMID:8175743, GO:0055078=GO_REF:0000019, GO:0004977=PMID:8175743, GO:0002027=GO_REF:0000019, GO:0042923=PMID:15927146, GO:0005887=PMID:8463333, GO:0007187=PMID:8175743, GO:0004980=PMID:19743876, GO:0008217=GO_REF:0000019, GO:0007188=GO_REF:0000019, GO:0017046=GO_REF:0000019, GO:0042309=GO_REF:0000019} P41968 Melanocortin receptor 3 protein 20100130 {GO:0005515=IPI, GO:0005886=TAS, GO:0030819=IDA, GO:0007200=TAS, GO:0055078=IEA, GO:0004977=TAS, GO:0002027=IEA, GO:0042923=IPI, GO:0005887=TAS, GO:0007187=TAS, GO:0004980=IPI, GO:0008217=IEA, GO:0007188=IEA, GO:0017046=IEA, GO:0042309=IEA} G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, homoiothermy, phospholipase C-activating G-protein coupled receptor signaling pathway, positive regulation of cAMP biosynthetic process, regulation of blood pressure, regulation of heart rate, sodium ion homeostasis integral to plasma membrane, plasma membrane melanocortin receptor activity, melanocyte-stimulating hormone receptor activity, neuropeptide binding, peptide hormone binding, protein binding Human MC4R BHF-UCL UniProtKB {GO:0005515=PMID:19329486, GO:0007631=GO_REF:0000019, GO:0032868=GO_REF:0000019, GO:0005886=Reactome:REACT_22268, GO:0030819=PMID:19329486, GO:2000252=GO_REF:0000019, GO:0002024=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0004977=PMID:8794897, GO:0006112=GO_REF:0000019, GO:0042923=PMID:15927146, GO:0045780=PMID:16614075, GO:0004980=PMID:19743876, GO:0007188=PMID:8794897, GO:0016021=GO_REF:0000037, GO:0017046=GO_REF:0000019, GO:0030073=GO_REF:0000019, GO:0031625=PMID:19737927} P32245 Melanocortin receptor 4 protein 20100130 {GO:0005515=IPI, GO:0007631=IEA, GO:0032868=IEA, GO:0005886=TAS, GO:0030819=IDA, GO:2000252=IEA, GO:0002024=IEA, GO:0005634=IEA, GO:0004977=TAS, GO:0006112=IEA, GO:0042923=IPI, GO:0045780=IMP, GO:0004980=IPI, GO:0007188=TAS, GO:0016021=IEA, GO:0017046=IEA, GO:0030073=IEA, GO:0031625=IPI} adenylate cyclase-modulating G-protein coupled receptor signaling pathway, diet induced thermogenesis, energy reserve metabolic process, feeding behavior, insulin secretion, negative regulation of feeding behavior, positive regulation of bone resorption, positive regulation of cAMP biosynthetic process, response to insulin stimulus integral to membrane, nucleus, plasma membrane melanocortin receptor activity, melanocyte-stimulating hormone receptor activity, neuropeptide binding, peptide hormone binding, protein binding, ubiquitin protein ligase binding Human MC5R BHF-UCL UniProtKB {GO:0005515=PMID:19329486, GO:0005886=Reactome:REACT_22268, GO:0007187=PMID:7739752, GO:0005887=PMID:7739752, GO:0030819=PMID:19329486, GO:0042562=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0004977=GO_REF:0000002} P33032 Melanocortin receptor 5 protein 20100130 {GO:0005515=IPI, GO:0005886=TAS, GO:0007187=TAS, GO:0005887=TAS, GO:0030819=IDA, GO:0042562=IEA, GO:0016021=IEA, GO:0004977=IEA} G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, positive regulation of cAMP biosynthetic process integral to membrane, integral to plasma membrane, plasma membrane hormone binding, melanocortin receptor activity, protein binding Human MCAM PINC UniProtKB {GO:0005886=PMID:8378324, GO:0003094=PMID:20354148, GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037, GO:0009653=PMID:8378324} P43121 Cell surface glycoprotein MUC18 protein 20040811 {GO:0005886=NAS, GO:0003094=IEP, GO:0016021=IEA, GO:0007155=IEA, GO:0009653=TAS} anatomical structure morphogenesis, cell adhesion, glomerular filtration integral to membrane, plasma membrane Human MCAT UniPathway UniProtKB {GO:0005739=PMID:12882974, GO:0008152=PMID:12882974, GO:0006633=GO_REF:0000041, GO:0004314=PMID:12882974, GO:0016740=PMID:12882974} Q8IVS2 Malonyl-CoA-acyl carrier protein transacylase, mitochondrial protein 20130413 {GO:0005739=IDA, GO:0008152=IDA, GO:0006633=IEA, GO:0004314=IDA, GO:0016740=IDA} fatty acid biosynthetic process, metabolic process mitochondrion "acyl-carrier-protein"" S-malonyltransferase activity, transferase activity""" Human UniPathway:UPA00094 MCC HPA UniProtKB {GO:0005515=PMID:21988832, GO:0007165=PMID:1848370, GO:0005737=GO_REF:0000052, GO:0005886=PMID:19555689, GO:0050680=PMID:18591935, GO:0004872=PMID:1848370, GO:0005634=PMID:18591935, GO:0016055=GO_REF:0000037, GO:0090090=PMID:18591935, GO:0010633=PMID:19555689} P23508 Colorectal mutant cancer protein protein 20111111 {GO:0005515=IPI, GO:0007165=TAS, GO:0005737=IDA, GO:0005886=IDA, GO:0050680=IDA, GO:0004872=TAS, GO:0005634=IDA, GO:0016055=IEA, GO:0090090=IDA, GO:0010633=IMP} Wnt receptor signaling pathway, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of epithelial cell migration, negative regulation of epithelial cell proliferation, signal transduction cytoplasm, nucleus, plasma membrane protein binding, receptor activity Human MCCC1 HPA UniProtKB {GO:0005743=Reactome:REACT_21275, GO:0006768=PMID:11401427, GO:0009083=Reactome:REACT_197, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000002, GO:0005739=GO_REF:0000052, GO:0034641=Reactome:REACT_13, GO:0004485=PMID:11170888, GO:0005759=PMID:11170888, GO:0009374=PMID:11401427, GO:0004075=GO_REF:0000002, GO:0006552=GO_REF:0000041} Q96RQ3 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial protein 20101115 {GO:0005743=TAS, GO:0006768=NAS, GO:0009083=TAS, GO:0044281=TAS, GO:0005524=IEA, GO:0046872=IEA, GO:0005739=IDA, GO:0034641=TAS, GO:0004485=NAS, GO:0005759=NAS, GO:0009374=NAS, GO:0004075=IEA, GO:0006552=IEA} biotin metabolic process, branched-chain amino acid catabolic process, cellular nitrogen compound metabolic process, leucine catabolic process, small molecule metabolic process mitochondrial inner membrane, mitochondrial matrix, mitochondrion ATP binding, biotin binding, biotin carboxylase activity, metal ion binding, methylcrotonoyl-CoA carboxylase activity Human MCCC2 Reactome UniProtKB {GO:0005739=PMID:11181649, GO:0034641=Reactome:REACT_13, GO:0004485=PMID:11170888, GO:0005759=GO_REF:0000039, GO:0016874=GO_REF:0000002, GO:0005743=Reactome:REACT_21275, GO:0009083=Reactome:REACT_197, GO:0044281=Reactome:REACT_111217, GO:0015936=GO_REF:0000019, GO:0006552=GO_REF:0000041, GO:0005524=GO_REF:0000037} Q9HCC0 Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial protein 20130121 {GO:0005739=NAS, GO:0034641=TAS, GO:0004485=NAS, GO:0005759=IEA, GO:0016874=IEA, GO:0005743=TAS, GO:0009083=TAS, GO:0044281=TAS, GO:0015936=IEA, GO:0006552=IEA, GO:0005524=IEA} branched-chain amino acid catabolic process, cellular nitrogen compound metabolic process, coenzyme A metabolic process, leucine catabolic process, small molecule metabolic process mitochondrial inner membrane, mitochondrial matrix, mitochondrion ATP binding, ligase activity, methylcrotonoyl-CoA carboxylase activity Human MCEE Reactome UniProtKB {GO:0005739=GO_REF:0000019, GO:0006635=Reactome:REACT_1473, GO:0004493=PMID:11481338, GO:0005759=Reactome:REACT_1909, GO:0019626=Reactome:REACT_993, GO:0044281=Reactome:REACT_111217, GO:0044255=Reactome:REACT_22279, GO:0046491=PMID:11481338} Q96PE7 Methylmalonyl-CoA epimerase, mitochondrial protein 20130301 {GO:0005739=IEA, GO:0006635=TAS, GO:0004493=IDA, GO:0005759=TAS, GO:0019626=TAS, GO:0044281=TAS, GO:0044255=TAS, GO:0046491=IDA} L-methylmalonyl-CoA metabolic process, cellular lipid metabolic process, fatty acid beta-oxidation, short-chain fatty acid catabolic process, small molecule metabolic process mitochondrial matrix, mitochondrion methylmalonyl-CoA epimerase activity Human MCF2 InterPro UniProtKB {GO:0005515=PMID:18470881, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0035023=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0006915=Reactome:REACT_13638, GO:0097190=Reactome:REACT_13720, GO:0005829=Reactome:REACT_19216, GO:0005622=GO_REF:0000002, GO:0035556=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0005089=GO_REF:0000002, GO:0005856=PMID:3056717} Q5JYJ7 DBL-transforming protein protein 20130413 {GO:0005515=IPI, GO:0051056=TAS, GO:0048011=TAS, GO:0035023=IEA, GO:0007264=TAS, GO:0006915=TAS, GO:0097190=TAS, GO:0005829=TAS, GO:0005622=IEA, GO:0035556=IEA, GO:0005543=IEA, GO:0016020=IEA, GO:0005089=IEA, GO:0005856=TAS} apoptotic process, apoptotic signaling pathway, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytoskeleton, cytosol, intracellular, membrane Rho guanyl-nucleotide exchange factor activity, phospholipid binding, protein binding Human InterPro:IPR001331 MCF2L Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0005886=GO_REF:0000039, GO:0007264=Reactome:REACT_11044, GO:0035023=GO_REF:0000002, GO:0006915=Reactome:REACT_13638, GO:0007266=GO_REF:0000019, GO:0097190=Reactome:REACT_13720, GO:0030027=GO_REF:0000019, GO:0005829=Reactome:REACT_19216, GO:0005622=GO_REF:0000002, GO:0035556=GO_REF:0000002, GO:0005545=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0016020=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0005089=GO_REF:0000019} O15068 Guanine nucleotide exchange factor DBS protein 20130301 {GO:0051056=TAS, GO:0048011=TAS, GO:0005886=IEA, GO:0007264=TAS, GO:0035023=IEA, GO:0006915=TAS, GO:0007266=IEA, GO:0097190=TAS, GO:0030027=IEA, GO:0005829=TAS, GO:0005622=IEA, GO:0035556=IEA, GO:0005545=IEA, GO:0005543=IEA, GO:0016020=IEA, GO:0045944=IEA, GO:0005089=IEA} Rho protein signal transduction, apoptotic process, apoptotic signaling pathway, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol, intracellular, lamellipodium, membrane, plasma membrane 1-phosphatidylinositol binding, Rho guanyl-nucleotide exchange factor activity, phospholipid binding Human MCF2L2 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0035023=GO_REF:0000002, GO:0005089=GO_REF:0000002} Q86YR7 Probable guanine nucleotide exchange factor MCF2L2 protein 20130413 {GO:0005622=IEA, GO:0005543=IEA, GO:0035023=IEA, GO:0005089=IEA} regulation of Rho protein signal transduction intracellular Rho guanyl-nucleotide exchange factor activity, phospholipid binding Human InterPro:IPR000219 MCFD2 Reactome UniProtKB {GO:0012507=Reactome:REACT_25176, GO:0005793=GO_REF:0000039, GO:0005794=GO_REF:0000039, GO:0005783=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0016192=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q8NI22 Multiple coagulation factor deficiency protein 2 protein 20101116 {GO:0012507=TAS, GO:0005793=IEA, GO:0005794=IEA, GO:0005783=IEA, GO:0005509=IEA, GO:0016192=IEA, GO:0015031=IEA, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS} cellular protein metabolic process, post-translational protein modification, protein N-linked glycosylation via asparagine, protein transport, vesicle-mediated transport ER to Golgi transport vesicle membrane, Golgi apparatus, endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment calcium ion binding Human MCHR1 BHF-UCL UniProtKB {GO:0007631=PMID:10421367, GO:0005886=Reactome:REACT_25247, GO:0051928=GO_REF:0000019, GO:0004930=PMID:10421367, GO:0030273=GO_REF:0000002, GO:0042562=GO_REF:0000019, GO:0031513=GO_REF:0000024, GO:0006091=PMID:10421367, GO:0008022=GO_REF:0000019, GO:0007204=GO_REF:0000019, GO:0007193=PMID:10421367, GO:0008188=PMID:10860944, GO:0007186=PMID:10421368, GO:0005887=PMID:10421367, GO:0007218=GO_REF:0000002, GO:0016021=GO_REF:0000002} Q99705 Melanin-concentrating hormone receptor 1 protein 20080517 {GO:0007631=TAS, GO:0005886=TAS, GO:0051928=IEA, GO:0004930=TAS, GO:0030273=IEA, GO:0042562=IEA, GO:0031513=ISS, GO:0006091=TAS, GO:0008022=IEA, GO:0007204=IEA, GO:0007193=TAS, GO:0008188=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0007218=IEA, GO:0016021=IEA} G-protein coupled receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, elevation of cytosolic calcium ion concentration, feeding behavior, generation of precursor metabolites and energy, neuropeptide signaling pathway, positive regulation of calcium ion transport integral to membrane, integral to plasma membrane, nonmotile primary cilium, plasma membrane G-protein coupled receptor activity, hormone binding, melanin-concentrating hormone receptor activity, neuropeptide receptor activity, protein C-terminus binding Human UniProtKB:Q8JZL2 MCHR2 Reactome UniProtKB {GO:0005886=Reactome:REACT_25247, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q969V1 Melanin-concentrating hormone receptor 2 protein 20101028 {GO:0005886=TAS, GO:0004930=IEA, GO:0016021=IEA} integral to membrane, plasma membrane G-protein coupled receptor activity Human MCL1 HPA UniProtKB {GO:0005515=PMID:23245996, GO:0043066=PMID:10837489, GO:0019725=PMID:10837489, GO:0046982=PMID:10837489, GO:0051434=PMID:21036904, GO:2001020=PMID:20467439, GO:0001709=PMID:10837489, GO:0006915=PMID:10837489, GO:0005634=PMID:20467439, GO:0007275=GO_REF:0000037, GO:0005741=PMID:10837489, GO:0005739=GO_REF:0000052, GO:0005737=PMID:10837489, GO:0016020=PMID:7896880, GO:0005759=GO_REF:0000019, GO:0097136=PMID:21199865, GO:2001240=PMID:20921992, GO:0005654=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0034097=PMID:9184696, GO:0015266=PMID:10837489} Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 protein 20080205 {GO:0005515=IPI, GO:0043066=TAS, GO:0019725=NAS, GO:0046982=IPI, GO:0051434=IPI, GO:2001020=IMP, GO:0001709=NAS, GO:0006915=IDA, GO:0005634=IDA, GO:0007275=IEA, GO:0005741=TAS, GO:0005739=IDA, GO:0005737=TAS, GO:0016020=IDA, GO:0005759=IEA, GO:0097136=IDA, GO:2001240=IMP, GO:0005654=IEA, GO:0016021=IEA, GO:0034097=IDA, GO:0015266=TAS} apoptotic process, cell fate determination, cellular homeostasis, multicellular organismal development, negative regulation of apoptotic process, negative regulation of extrinsic apoptotic signaling pathway in absence of ligand, regulation of response to DNA damage stimulus, response to cytokine stimulus Bcl-2 family protein complex, cytoplasm, integral to membrane, membrane, mitochondrial matrix, mitochondrial outer membrane, mitochondrion, nucleoplasm, nucleus BH3 domain binding, protein binding, protein channel activity, protein heterodimerization activity Human MCM10 HPA UniProtKB {GO:0005515=PMID:16189514, GO:0006260=Reactome:REACT_6769, GO:0000082=Reactome:REACT_1783, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_6750, GO:0005634=GO_REF:0000052, GO:0000278=Reactome:REACT_152, GO:0003677=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q7L590 Protein MCM10 homolog protein 20111111 {GO:0005515=IPI, GO:0006260=TAS, GO:0000082=TAS, GO:0005737=IDA, GO:0005730=IDA, GO:0000075=TAS, GO:0005654=TAS, GO:0005634=IDA, GO:0000278=TAS, GO:0003677=IEA, GO:0046872=IEA} DNA replication, G1/S transition of mitotic cell cycle, cell cycle checkpoint, mitotic cell cycle cytoplasm, nucleolus, nucleoplasm, nucleus DNA binding, metal ion binding, protein binding Human MCM2 IntAct UniProtKB {GO:0005515=PMID:17296731, GO:0042555=PMID:17296731, GO:0006334=GO_REF:0000019, GO:0005634=PMID:16899510, GO:0003688=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0003677=PMID:8175912, GO:0003678=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0006260=Reactome:REACT_6769, GO:0000084=Reactome:REACT_899, GO:0042393=GO_REF:0000019, GO:0006271=Reactome:REACT_932, GO:0000082=Reactome:REACT_1783, GO:0007049=PMID:8175912, GO:0006270=PMID:16899510, GO:0006268=GO_REF:0000019, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_6750, GO:0005664=GO_REF:0000019, GO:0000278=Reactome:REACT_152, GO:0000785=PMID:16899510} P49736 DNA replication licensing factor MCM2 protein 20130415 {GO:0005515=IPI, GO:0042555=IDA, GO:0006334=IEA, GO:0005634=IDA, GO:0003688=IEA, GO:0005524=IEA, GO:0003677=TAS, GO:0003678=IEA, GO:0046872=IEA, GO:0006260=TAS, GO:0000084=TAS, GO:0042393=IEA, GO:0006271=TAS, GO:0000082=TAS, GO:0007049=TAS, GO:0006270=IMP, GO:0006268=IEA, GO:0000075=TAS, GO:0005654=TAS, GO:0005664=IEA, GO:0000278=TAS, GO:0000785=IDA} DNA replication, DNA replication initiation, DNA strand elongation involved in DNA replication, DNA unwinding involved in replication, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, cell cycle, cell cycle checkpoint, mitotic cell cycle, nucleosome assembly MCM complex, chromatin, nuclear origin of replication recognition complex, nucleoplasm, nucleus ATP binding, DNA binding, DNA helicase activity, DNA replication origin binding, histone binding, metal ion binding, protein binding Human UniProtKB:Q14566 MCM3 HPA UniProtKB {GO:0005515=PMID:17296731, GO:0042555=PMID:17296731, GO:0048471=PMID:20531406, GO:0005813=GO_REF:0000052, GO:0005658=PMID:1549468, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0003678=GO_REF:0000002, GO:0043231=GO_REF:0000052, GO:0006260=GO_REF:0000002, GO:0000084=Reactome:REACT_899, GO:0006271=Reactome:REACT_932, GO:0000082=Reactome:REACT_1783, GO:0006270=GO_REF:0000002, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_6750, GO:0000278=Reactome:REACT_152} Q7Z6P5 DNA replication licensing factor MCM3 protein 20080205 {GO:0005515=IPI, GO:0042555=IDA, GO:0048471=IDA, GO:0005813=IDA, GO:0005658=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0005524=IEA, GO:0003678=IEA, GO:0043231=IDA, GO:0006260=IEA, GO:0000084=TAS, GO:0006271=TAS, GO:0000082=TAS, GO:0006270=IEA, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS} DNA replication, DNA replication initiation, DNA strand elongation involved in DNA replication, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, cell cycle checkpoint, mitotic cell cycle MCM complex, alpha DNA polymerase:primase complex, centrosome, intracellular membrane-bounded organelle, nucleolus, nucleoplasm, nucleus, perinuclear region of cytoplasm ATP binding, DNA binding, DNA helicase activity, protein binding Human MCM3AP PINC UniProtKB {GO:0006260=PMID:9712829, GO:0005737=GO_REF:0000019, GO:0005634=PMID:16780588, GO:0006606=PMID:9712829, GO:0003677=PMID:9712829, GO:0005829=PMID:16780588} O60318 80 kDa MCM3-associated protein protein 20030904 {GO:0006260=TAS, GO:0005737=IEA, GO:0005634=IDA, GO:0006606=TAS, GO:0003677=TAS, GO:0005829=IDA} DNA replication, protein import into nucleus cytoplasm, cytosol, nucleus DNA binding Human MCM4 HPA UniProtKB {GO:0005515=PMID:22190034, GO:0042555=PMID:17296731, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000038, GO:0005524=GO_REF:0000029, GO:0003678=GO_REF:0000002, GO:0006260=Reactome:REACT_6769, GO:0000084=Reactome:REACT_899, GO:0006271=Reactome:REACT_932, GO:0000082=Reactome:REACT_1783, GO:0004003=PMID:9305914, GO:0003697=GO_REF:0000019, GO:0006270=GO_REF:0000002, GO:0006268=GO_REF:0000019, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_6750, GO:0000278=Reactome:REACT_152} P33991 DNA replication licensing factor MCM4 protein 20080818 {GO:0005515=IPI, GO:0042555=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0005524=NAS, GO:0003678=IEA, GO:0006260=TAS, GO:0000084=TAS, GO:0006271=TAS, GO:0000082=TAS, GO:0004003=IDA, GO:0003697=IEA, GO:0006270=IEA, GO:0006268=IEA, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS} DNA replication, DNA replication initiation, DNA strand elongation involved in DNA replication, DNA unwinding involved in replication, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, cell cycle checkpoint, mitotic cell cycle MCM complex, nucleolus, nucleoplasm, nucleus ATP binding, ATP-dependent DNA helicase activity, DNA binding, DNA helicase activity, protein binding, single-stranded DNA binding NOT Human MCM5 IntAct UniProtKB {GO:0005515=PMID:17296731, GO:0042555=PMID:17296731, GO:0005634=PMID:8751386, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0003678=GO_REF:0000002, GO:0006260=Reactome:REACT_6769, GO:0000084=Reactome:REACT_899, GO:0006271=Reactome:REACT_932, GO:0000082=Reactome:REACT_1783, GO:0006270=GO_REF:0000002, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_6750, GO:0000278=Reactome:REACT_152, GO:0051301=GO_REF:0000038} P33992 DNA replication licensing factor MCM5 protein 20130415 {GO:0005515=IPI, GO:0042555=IDA, GO:0005634=TAS, GO:0003677=IEA, GO:0005524=IEA, GO:0003678=IEA, GO:0006260=TAS, GO:0000084=TAS, GO:0006271=TAS, GO:0000082=TAS, GO:0006270=IEA, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0051301=IEA} DNA replication, DNA replication initiation, DNA strand elongation involved in DNA replication, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, cell cycle checkpoint, cell division, mitotic cell cycle MCM complex, nucleoplasm, nucleus ATP binding, DNA binding, DNA helicase activity, protein binding Human UniProtKB:P49736 MCM6 HPA UniProtKB {GO:0005515=PMID:22190034, GO:0042555=PMID:17296731, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005524=PMID:9286856, GO:0042802=PMID:16189514, GO:0006260=Reactome:REACT_6769, GO:0000084=Reactome:REACT_899, GO:0006271=Reactome:REACT_932, GO:0000082=Reactome:REACT_1783, GO:0004003=PMID:9305914, GO:0003697=GO_REF:0000019, GO:0006270=GO_REF:0000002, GO:0006268=GO_REF:0000019, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_6750, GO:0000278=Reactome:REACT_152} Q14566 DNA replication licensing factor MCM6 protein 20101115 {GO:0005515=IPI, GO:0042555=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0005524=NAS, GO:0042802=IPI, GO:0006260=TAS, GO:0000084=TAS, GO:0006271=TAS, GO:0000082=TAS, GO:0004003=IDA, GO:0003697=IEA, GO:0006270=IEA, GO:0006268=IEA, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS} DNA replication, DNA replication initiation, DNA strand elongation involved in DNA replication, DNA unwinding involved in replication, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, cell cycle checkpoint, mitotic cell cycle MCM complex, nucleolus, nucleoplasm, nucleus ATP binding, ATP-dependent DNA helicase activity, identical protein binding, protein binding, single-stranded DNA binding NOT Human MCM7 IntAct UniProtKB {GO:0005515=PMID:17314511, GO:0042555=PMID:17296731, GO:0008283=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0003677=PMID:15538388, GO:0005524=GO_REF:0000037, GO:0006974=PMID:15538388, GO:0003678=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0006260=Reactome:REACT_6769, GO:0000084=Reactome:REACT_899, GO:0042325=PMID:15538388, GO:0006271=Reactome:REACT_932, GO:0000082=Reactome:REACT_1783, GO:0004003=PMID:9305914, GO:0003697=GO_REF:0000019, GO:0006270=GO_REF:0000002, GO:0071364=GO_REF:0000019, GO:0006268=GO_REF:0000019, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_6750, GO:0000278=Reactome:REACT_152, GO:0000785=PMID:8798650} P33993 DNA replication licensing factor MCM7 protein 20130415 {GO:0005515=IPI, GO:0042555=IDA, GO:0008283=IEA, GO:0042493=IEA, GO:0005634=IEA, GO:0003677=TAS, GO:0005524=IEA, GO:0006974=IMP, GO:0003678=IEA, GO:0005829=IEA, GO:0006260=TAS, GO:0000084=TAS, GO:0042325=IMP, GO:0006271=TAS, GO:0000082=TAS, GO:0004003=IDA, GO:0003697=IEA, GO:0006270=IEA, GO:0071364=IEA, GO:0006268=IEA, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000785=TAS} DNA replication, DNA replication initiation, DNA strand elongation involved in DNA replication, DNA unwinding involved in replication, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, cell cycle checkpoint, cell proliferation, cellular response to epidermal growth factor stimulus, mitotic cell cycle, regulation of phosphorylation, response to DNA damage stimulus, response to drug MCM complex, chromatin, cytosol, nucleoplasm, nucleus ATP binding, ATP-dependent DNA helicase activity, DNA binding, DNA helicase activity, protein binding, single-stranded DNA binding Human UniProtKB:P01106 MCM8 Reactome UniProtKB {GO:0004386=GO_REF:0000037, GO:0007292=GO_REF:0000024, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0006974=PMID:22771115, GO:0006260=Reactome:REACT_6769, GO:0000084=Reactome:REACT_899, GO:0048232=GO_REF:0000024, GO:0006271=Reactome:REACT_932, GO:0000082=Reactome:REACT_1783, GO:0000724=GO_REF:0000019, GO:0097362=PMID:22771115, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_6750, GO:0000278=Reactome:REACT_152} Q9UJA3 DNA helicase MCM8 protein 20130301 {GO:0004386=IEA, GO:0007292=ISS, GO:0003677=IEA, GO:0005524=IEA, GO:0006974=IDA, GO:0006260=TAS, GO:0000084=TAS, GO:0048232=ISS, GO:0006271=TAS, GO:0000082=TAS, GO:0000724=IEA, GO:0097362=IDA, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS} DNA replication, DNA strand elongation involved in DNA replication, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, cell cycle checkpoint, double-strand break repair via homologous recombination, female gamete generation, male gamete generation, mitotic cell cycle, response to DNA damage stimulus MCM8-MCM9 complex, nucleoplasm ATP binding, DNA binding, helicase activity Human MCM9 UniProtKB UniProtKB {GO:0006260=GO_REF:0000002, GO:0000724=PMID:22771115, GO:0097362=PMID:22771115, GO:0004386=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0007292=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0006974=PMID:22771115} Q9NXL9 DNA helicase MCM9 protein 20120727 {GO:0006260=IEA, GO:0000724=IDA, GO:0097362=IDA, GO:0004386=IEA, GO:0005634=IEA, GO:0007292=ISS, GO:0005524=IEA, GO:0003677=IEA, GO:0006974=IDA} DNA replication, double-strand break repair via homologous recombination, female gamete generation, response to DNA damage stimulus MCM8-MCM9 complex, nucleus ATP binding, DNA binding, helicase activity Human MCMBP HPA UniProtKB {GO:0000084=PMID:17296731, GO:0006261=PMID:21196493, GO:0042555=PMID:17296731, GO:0005737=GO_REF:0000052, GO:0007067=GO_REF:0000037, GO:0005886=GO_REF:0000052, GO:0003682=PMID:17296731, GO:0005730=GO_REF:0000052, GO:0007062=PMID:20090939, GO:0005634=GO_REF:0000052, GO:0051301=GO_REF:0000037} Q9BTE3 Mini-chromosome maintenance complex-binding protein protein 20110516 {GO:0000084=TAS, GO:0006261=IMP, GO:0042555=IDA, GO:0005737=IDA, GO:0007067=IEA, GO:0005886=IDA, GO:0003682=IDA, GO:0005730=IDA, GO:0007062=IMP, GO:0005634=IDA, GO:0051301=IEA} DNA-dependent DNA replication, S phase of mitotic cell cycle, cell division, mitosis, sister chromatid cohesion MCM complex, cytoplasm, nucleolus, nucleus, plasma membrane chromatin binding Human MCOLN1 HPA UniProtKB {GO:0005261=PMID:11030752, GO:0005886=GO_REF:0000052, GO:0005765=GO_REF:0000039, GO:0055085=Reactome:REACT_15518, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0005737=GO_REF:0000052, GO:0005887=PMID:11013137, GO:0031902=GO_REF:0000039, GO:0006816=GO_REF:0000037, GO:0016021=PMID:11030752, GO:0006812=PMID:11030752, GO:0010008=Reactome:REACT_25069} Q9GZU1 Mucolipin-1 protein 20101115 {GO:0005261=NAS, GO:0005886=IDA, GO:0005765=IEA, GO:0055085=TAS, GO:0006879=TAS, GO:0033572=TAS, GO:0005737=IDA, GO:0005887=NAS, GO:0031902=IEA, GO:0006816=IEA, GO:0016021=NAS, GO:0006812=NAS, GO:0010008=TAS} calcium ion transport, cation transport, cellular iron ion homeostasis, transferrin transport, transmembrane transport cytoplasm, endosome membrane, integral to membrane, integral to plasma membrane, late endosome membrane, lysosomal membrane, plasma membrane cation channel activity Human MCOLN3 ENSEMBL UniProtKB {GO:0005737=GO_REF:0000019, GO:0042491=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0006811=GO_REF:0000037} Q8TDD5 Mucolipin-3 protein 20130413 {GO:0005737=IEA, GO:0042491=IEA, GO:0005886=IEA, GO:0007626=IEA, GO:0016021=IEA, GO:0006811=IEA} auditory receptor cell differentiation, ion transport, locomotory behavior cytoplasm, integral to membrane, plasma membrane Human Ensembl:ENSMUSP00000038801 MCPH1 UniProtKB UniProtKB {GO:0010468=GO_REF:0000019, GO:0005737=GO_REF:0000037, GO:0005815=GO_REF:0000039, GO:0043549=GO_REF:0000019} Q8NEM0 Microcephalin protein 20130413 {GO:0010468=IEA, GO:0005737=IEA, GO:0005815=IEA, GO:0043549=IEA} regulation of gene expression, regulation of kinase activity cytoplasm, microtubule organizing center Human UniProtKB-SubCell:SL-0048 MCRS1 HPA UniProtKB {GO:0005515=PMID:19060904, GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006310=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0043981=PMID:20018852, GO:0031011=PMID:21303910, GO:0005737=PMID:9765390, GO:0043982=PMID:20018852, GO:0006281=GO_REF:0000037, GO:0043984=PMID:20018852, GO:0043996=PMID:20018852, GO:0071339=PMID:15960975, GO:0043995=PMID:20018852, GO:0000123=PMID:20018852, GO:0005654=PMID:9765390, GO:0046972=PMID:20018852, GO:0006464=PMID:9765390} Q96EZ8 Microspherule protein 1 protein 20120912 {GO:0005515=IPI, GO:0006355=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006310=IEA, GO:0006351=IEA, GO:0043981=IDA, GO:0031011=IDA, GO:0005737=TAS, GO:0043982=IDA, GO:0006281=IEA, GO:0043984=IDA, GO:0043996=IDA, GO:0071339=IDA, GO:0043995=IDA, GO:0000123=IDA, GO:0005654=TAS, GO:0046972=IDA, GO:0006464=TAS} DNA recombination, DNA repair, cellular protein modification process, histone H4-K16 acetylation, histone H4-K5 acetylation, histone H4-K8 acetylation, regulation of transcription, DNA-dependent, transcription, DNA-dependent Ino80 complex, MLL1 complex, cytoplasm, histone acetyltransferase complex, nucleolus, nucleoplasm, nucleus histone acetyltransferase activity (H4-K16 specific), histone acetyltransferase activity (H4-K5 specific), histone acetyltransferase activity (H4-K8 specific), protein binding NOT Human MCTP2 HGNC UniProtKB {GO:0005544=PMID:15528213, GO:0019722=PMID:15528213, GO:0005509=PMID:15528213, GO:0016021=PMID:15528213} Q6DN12 Multiple C2 and transmembrane domain-containing protein 2 protein 20051208 {GO:0005544=IDA, GO:0019722=NAS, GO:0005509=IDA, GO:0016021=IDA} calcium-mediated signaling integral to membrane calcium ion binding, calcium-dependent phospholipid binding Human MCTS1 PINC UniProtKB {GO:0008284=PMID:9766643, GO:0005737=GO_REF:0000039, GO:0007049=GO_REF:0000037, GO:0006355=GO_REF:0000037, GO:0003723=GO_REF:0000002, GO:0040008=GO_REF:0000037, GO:0006974=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9ULC4 Malignant T-cell-amplified sequence 1 protein 20030904 {GO:0008284=TAS, GO:0005737=IEA, GO:0007049=IEA, GO:0006355=IEA, GO:0003723=IEA, GO:0040008=IEA, GO:0006974=IEA, GO:0006351=IEA} cell cycle, positive regulation of cell proliferation, regulation of growth, regulation of transcription, DNA-dependent, response to DNA damage stimulus, transcription, DNA-dependent cytoplasm RNA binding Human MCU HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005515=PMID:23178883, GO:0005262=PMID:21685888, GO:0035786=PMID:21685886, GO:0019722=PMID:21685886, GO:0006851=PMID:21685888, GO:0051561=PMID:21685888, GO:0005743=PMID:21685888, GO:0032024=PMID:22829870, GO:0042593=PMID:22829870, GO:0016021=GO_REF:0000037, GO:0015292=PMID:21685888} Q8NE86 Calcium uniporter protein, mitochondrial protein 20090616 {GO:0005739=IDA, GO:0005515=IPI, GO:0005262=IDA, GO:0035786=IDA, GO:0019722=IDA, GO:0006851=IDA, GO:0051561=IDA, GO:0005743=IDA, GO:0032024=IMP, GO:0042593=IMP, GO:0016021=IEA, GO:0015292=IDA} calcium-mediated signaling, elevation of mitochondrial calcium ion concentration, glucose homeostasis, mitochondrial calcium ion transport, positive regulation of insulin secretion, protein complex oligomerization integral to membrane, mitochondrial inner membrane, mitochondrion calcium channel activity, protein binding, uniporter activity Human MDC1 HPA UniProtKB {GO:0005515=PMID:19804756, GO:0006281=Reactome:REACT_216, GO:0000724=Reactome:REACT_1874, GO:0005694=GO_REF:0000024, GO:0031573=PMID:17577209, GO:0005730=GO_REF:0000052, GO:0070975=PMID:20008512, GO:0005654=Reactome:REACT_1809, GO:0005634=GO_REF:0000052, GO:0008022=PMID:17577209, GO:0005925=GO_REF:0000052, GO:0006302=Reactome:REACT_2054} Q14676 Mediator of DNA damage checkpoint protein 1 protein 20120912 {GO:0005515=IPI, GO:0006281=TAS, GO:0000724=TAS, GO:0005694=ISS, GO:0031573=TAS, GO:0005730=IDA, GO:0070975=IPI, GO:0005654=TAS, GO:0005634=IDA, GO:0008022=IPI, GO:0005925=IDA, GO:0006302=TAS} DNA repair, double-strand break repair, double-strand break repair via homologous recombination, intra-S DNA damage checkpoint chromosome, focal adhesion, nucleolus, nucleoplasm, nucleus FHA domain binding, protein C-terminus binding, protein binding Human MDFI IntAct UniProtKB {GO:0005515=PMID:19447967, GO:0060707=GO_REF:0000019, GO:0030178=GO_REF:0000024, GO:0048704=GO_REF:0000019, GO:0005634=GO_REF:0000024, GO:0042994=PMID:8797820, GO:0000122=GO_REF:0000024, GO:0007257=GO_REF:0000019, GO:0009790=PMID:8797820, GO:0009950=GO_REF:0000024, GO:0043392=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0008134=GO_REF:0000019} Q99750 MyoD family inhibitor protein 20130415 {GO:0005515=IPI, GO:0060707=IEA, GO:0030178=ISS, GO:0048704=IEA, GO:0005634=ISS, GO:0042994=TAS, GO:0000122=ISS, GO:0007257=IEA, GO:0009790=TAS, GO:0009950=ISS, GO:0043392=ISS, GO:0005737=IEA, GO:0008134=IEA} activation of JUN kinase activity, cytoplasmic sequestering of transcription factor, dorsal/ventral axis specification, embryo development, embryonic skeletal system morphogenesis, negative regulation of DNA binding, negative regulation of Wnt receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, trophoblast giant cell differentiation cytoplasm, nucleus protein binding, transcription factor binding Human UniProtKB:Q9UBX3 MDFIC HPA UniProtKB {GO:0005515=PMID:12192039, GO:0005794=GO_REF:0000052, GO:0030111=PMID:12192039, GO:0030332=PMID:12944466, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0007257=PMID:12192039, GO:0030957=PMID:12944466, GO:0006351=GO_REF:0000037, GO:0050434=PMID:10671520, GO:0019048=GO_REF:0000037, GO:0042308=GO_REF:0000024, GO:0045893=PMID:12944466, GO:0045892=GO_REF:0000024, GO:0008134=PMID:12192039} Q9P1T7 MyoD family inhibitor domain-containing protein protein 20110516 {GO:0005515=IPI, GO:0005794=IDA, GO:0030111=IDA, GO:0030332=IPI, GO:0005730=IDA, GO:0005634=IDA, GO:0007257=IDA, GO:0030957=IDA, GO:0006351=IEA, GO:0050434=IDA, GO:0019048=IEA, GO:0042308=ISS, GO:0045893=IDA, GO:0045892=ISS, GO:0008134=IPI} activation of JUN kinase activity, negative regulation of protein import into nucleus, negative regulation of transcription, DNA-dependent, positive regulation of transcription, DNA-dependent, positive regulation of viral transcription, regulation of Wnt receptor signaling pathway, transcription, DNA-dependent, virus-host interaction Golgi apparatus, nucleolus, nucleus Tat protein binding, cyclin binding, protein binding, transcription factor binding Human MDGA1 HGNC UniProtKB {GO:0003674=GO_REF:0000015, GO:0016020=GO_REF:0000002, GO:0007420=PMID:15019943, GO:0001764=GO_REF:0000024, GO:0046658=PMID:15019943, GO:0021527=PMID:15019943} Q8NFP4 MAM domain-containing glycosylphosphatidylinositol anchor protein 1 protein 20070720 {GO:0003674=ND, GO:0016020=IEA, GO:0007420=ISS, GO:0001764=ISS, GO:0046658=ISS, GO:0021527=ISS} brain development, neuron migration, spinal cord association neuron differentiation anchored to plasma membrane, membrane molecular_function Human UniProtKB:P85171 MDGA2 HGNC UniProtKB {GO:0021522=PMID:15019943, GO:0005886=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0031225=GO_REF:0000037} Q7Z553 MAM domain-containing glycosylphosphatidylinositol anchor protein 2 protein 20070720 {GO:0021522=ISS, GO:0005886=IEA, GO:0016020=IEA, GO:0031225=IEA} spinal cord motor neuron differentiation anchored to membrane, membrane, plasma membrane Human UniProtKB:P60756 MDH1 HPA UniProtKB {GO:0005813=GO_REF:0000052, GO:0006099=GO_REF:0000037, GO:0044262=GO_REF:0000002, GO:0004470=PMID:8786100, GO:0005975=Reactome:REACT_474, GO:0006094=Reactome:REACT_1520, GO:0016615=GO_REF:0000002, GO:0006107=GO_REF:0000019, GO:0006108=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_11216, GO:0016616=GO_REF:0000002, GO:0006734=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0051287=GO_REF:0000019, GO:0047860=GO_REF:0000003, GO:0006006=Reactome:REACT_723, GO:0030060=Reactome:REACT_11216} P40925 Malate dehydrogenase, cytoplasmic protein 20120912 {GO:0005813=IDA, GO:0006099=IEA, GO:0044262=IEA, GO:0004470=TAS, GO:0005975=TAS, GO:0006094=TAS, GO:0016615=IEA, GO:0006107=IEA, GO:0006108=IEA, GO:0044281=TAS, GO:0005829=TAS, GO:0016616=IEA, GO:0006734=IEA, GO:0005739=IEA, GO:0005737=IDA, GO:0051287=IEA, GO:0047860=IEA, GO:0006006=TAS, GO:0030060=TAS} NADH metabolic process, carbohydrate metabolic process, cellular carbohydrate metabolic process, gluconeogenesis, glucose metabolic process, malate metabolic process, oxaloacetate metabolic process, small molecule metabolic process, tricarboxylic acid cycle centrosome, cytoplasm, cytosol, mitochondrion L-malate dehydrogenase activity, NAD binding, diiodophenylpyruvate reductase activity, malate dehydrogenase activity, malic enzyme activity, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Human MDH2 HPA UniProtKB {GO:0044262=GO_REF:0000002, GO:0006099=Reactome:REACT_1785, GO:0046554=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0005975=Reactome:REACT_474, GO:0006094=Reactome:REACT_1520, GO:0005730=GO_REF:0000052, GO:0005743=GO_REF:0000019, GO:0006107=GO_REF:0000019, GO:0006108=PMID:16740313, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0043621=GO_REF:0000019, GO:0006734=GO_REF:0000019, GO:0005739=GO_REF:0000052, GO:0005759=Reactome:REACT_11169, GO:0006006=Reactome:REACT_723, GO:0030060=Reactome:REACT_11169, GO:0006475=PMID:20167786} P40926 Malate dehydrogenase, mitochondrial protein 20100326 {GO:0044262=IEA, GO:0006099=TAS, GO:0046554=IEA, GO:0005886=IDA, GO:0005975=TAS, GO:0006094=TAS, GO:0005730=IDA, GO:0005743=IEA, GO:0006107=IEA, GO:0006108=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0043621=IEA, GO:0006734=IEA, GO:0005739=IDA, GO:0005759=TAS, GO:0006006=TAS, GO:0030060=EXP, GO:0006475=IDA} NADH metabolic process, carbohydrate metabolic process, cellular carbohydrate metabolic process, gluconeogenesis, glucose metabolic process, internal protein amino acid acetylation, malate metabolic process, oxaloacetate metabolic process, small molecule metabolic process, tricarboxylic acid cycle mitochondrial inner membrane, mitochondrial matrix, mitochondrion, nucleolus, nucleus, plasma membrane L-malate dehydrogenase activity, malate dehydrogenase (NADP+) activity, protein self-association Human MDK InterPro UniProtKB {GO:0021542=GO_REF:0000019, GO:0030421=GO_REF:0000019, GO:0021987=GO_REF:0000019, GO:0030325=GO_REF:0000024, GO:0007614=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0009611=GO_REF:0000024, GO:0005576=GO_REF:0000039, GO:0051384=GO_REF:0000019, GO:0030154=PMID:1639750, GO:0007399=PMID:9384573, GO:0007165=PMID:7835084, GO:0016477=GO_REF:0000019, GO:0050795=GO_REF:0000019, GO:0021681=GO_REF:0000019, GO:0000087=GO_REF:0000019, GO:0051781=GO_REF:0000037, GO:0001662=GO_REF:0000019, GO:0045893=GO_REF:0000019, GO:0008201=PMID:9384573, GO:0008083=GO_REF:0000002} Q2LEK4 Midkine protein 20130413 {GO:0021542=IEA, GO:0030421=IEA, GO:0021987=IEA, GO:0030325=ISS, GO:0007614=IEA, GO:0042493=IEA, GO:0009611=ISS, GO:0005576=IEA, GO:0051384=IEA, GO:0030154=NAS, GO:0007399=NAS, GO:0007165=NAS, GO:0016477=IEA, GO:0050795=IEA, GO:0021681=IEA, GO:0000087=IEA, GO:0051781=IEA, GO:0001662=IEA, GO:0045893=IEA, GO:0008201=IDA, GO:0008083=IEA} M phase of mitotic cell cycle, adrenal gland development, behavioral fear response, cell differentiation, cell migration, cerebellar granular layer development, cerebral cortex development, defecation, dentate gyrus development, nervous system development, positive regulation of cell division, positive regulation of transcription, DNA-dependent, regulation of behavior, response to drug, response to glucocorticoid stimulus, response to wounding, short-term memory, signal transduction extracellular region growth factor activity, heparin binding Human InterPro:IPR000762|InterPro:IPR020089|InterPro:IPR020090|InterPro:IPR020091 MDM2 InterPro UniProtKB {GO:0005515=PMID:19372219, GO:0071157=GO_REF:0000002, GO:0034504=PMID:10360174, GO:0004842=PMID:9450543, GO:0070301=GO_REF:0000019, GO:0045202=GO_REF:0000019, GO:0071301=GO_REF:0000019, GO:0042220=GO_REF:0000019, GO:0042802=PMID:22493164, GO:0009743=GO_REF:0000019, GO:0042787=PMID:11278372, GO:0007173=Reactome:REACT_9417, GO:0010039=GO_REF:0000019, GO:0032026=GO_REF:0000019, GO:0046677=PMID:20810912, GO:0006977=Reactome:REACT_1625, GO:0071312=GO_REF:0000019, GO:0071391=GO_REF:0000019, GO:0043278=GO_REF:0000019, GO:0000122=GO_REF:0000002, GO:0007089=GO_REF:0000019, GO:0043234=PMID:9529249, GO:0045931=PMID:17290220, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0000075=Reactome:REACT_1538, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_988, GO:0019899=PMID:17290220, GO:0045892=PMID:9271120, GO:0045472=GO_REF:0000019, GO:0008284=PMID:7791904, GO:0016567=GO_REF:0000002, GO:0005886=Reactome:REACT_18393, GO:0032436=PMID:11278372, GO:0007268=Reactome:REACT_13685, GO:0005634=GO_REF:0000002, GO:0042975=GO_REF:0000019, GO:0045184=PMID:10360174, GO:0005829=Reactome:REACT_147833, GO:0031648=PMID:9529249, GO:0046827=GO_REF:0000019, GO:0002039=PMID:9529249, GO:0005737=PMID:21726810, GO:0071375=GO_REF:0000019, GO:0097110=GO_REF:0000019, GO:0043154=GO_REF:0000019, GO:0071236=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0043066=GO_REF:0000002, GO:0042176=PMID:9153395, GO:0048015=Reactome:REACT_12464, GO:0042493=GO_REF:0000019, GO:0005730=PMID:22869143, GO:0071456=PMID:20810912, GO:0071494=GO_REF:0000019, GO:0030666=Reactome:REACT_18393, GO:0010628=GO_REF:0000019, GO:0016604=PMID:10360174, GO:0006461=PMID:12915590, GO:0019048=GO_REF:0000037, GO:0071229=GO_REF:0000019, GO:0043518=PMID:9529249, GO:0010955=GO_REF:0000019} Q9H4C5 E3 ubiquitin-protein ligase Mdm2 protein 20130413 {GO:0005515=IPI, GO:0071157=IEA, GO:0034504=IDA, GO:0004842=IDA, GO:0070301=IEA, GO:0045202=IEA, GO:0071301=IEA, GO:0042220=IEA, GO:0042802=IPI, GO:0009743=IEA, GO:0042787=IDA, GO:0007173=TAS, GO:0010039=IEA, GO:0032026=IEA, GO:0046677=IEP, GO:0006977=TAS, GO:0071312=IEA, GO:0071391=IEA, GO:0043278=IEA, GO:0000122=IEA, GO:0007089=IEA, GO:0043234=IDA, GO:0045931=IMP, GO:0008543=TAS, GO:0045087=TAS, GO:0000075=TAS, GO:0008270=IEA, GO:0005654=TAS, GO:0019899=IPI, GO:0045892=IDA, GO:0045472=IEA, GO:0008284=TAS, GO:0016567=IEA, GO:0005886=TAS, GO:0032436=IDA, GO:0007268=TAS, GO:0005634=IEA, GO:0042975=IEA, GO:0045184=IDA, GO:0005829=TAS, GO:0031648=IDA, GO:0046827=IEA, GO:0002039=IPI, GO:0005737=IMP, GO:0071375=IEA, GO:0097110=IEA, GO:0043154=IEA, GO:0071236=IEA, GO:0048011=TAS, GO:0043066=IEA, GO:0042176=IDA, GO:0048015=TAS, GO:0042493=IEA, GO:0005730=IDA, GO:0071456=IEP, GO:0071494=IEA, GO:0030666=TAS, GO:0010628=IEA, GO:0016604=IDA, GO:0006461=IDA, GO:0019048=IEA, GO:0071229=IEA, GO:0043518=IDA, GO:0010955=IEA} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, cell cycle checkpoint, cellular response to UV-C, cellular response to acid, cellular response to alkaloid, cellular response to antibiotic, cellular response to estrogen stimulus, cellular response to hydrogen peroxide, cellular response to hypoxia, cellular response to peptide hormone stimulus, cellular response to vitamin B1, epidermal growth factor receptor signaling pathway, establishment of protein localization, fibroblast growth factor receptor signaling pathway, innate immune response, negative regulation of DNA damage response, signal transduction by p53 class mediator, negative regulation of apoptotic process, negative regulation of cell cycle arrest, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of protein processing, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of cell proliferation, positive regulation of gene expression, positive regulation of mitotic cell cycle, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of protein export from nucleus, protein complex assembly, protein destabilization, protein localization to nucleus, protein ubiquitination, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, regulation of protein catabolic process, response to antibiotic, response to carbohydrate stimulus, response to cocaine, response to drug, response to ether, response to iron ion, response to magnesium ion, response to morphine, synaptic transmission, traversing start control point of mitotic cell cycle, virus-host interaction cytoplasm, cytosol, endocytic vesicle membrane, nuclear body, nucleolus, nucleoplasm, nucleus, plasma membrane, protein complex, synapse enzyme binding, identical protein binding, p53 binding, peroxisome proliferator activated receptor binding, protein binding, scaffold protein binding, ubiquitin-protein ligase activity, zinc ion binding Human InterPro:IPR016495 MDM4 InterPro UniProtKB {GO:0005515=PMID:22493164, GO:0071157=GO_REF:0000002, GO:0043066=GO_REF:0000002, GO:0008284=GO_REF:0000019, GO:0008285=PMID:9226370, GO:0042177=PMID:10608892, GO:0008283=PMID:12101245, GO:0050821=PMID:10608892, GO:0071456=PMID:20810912, GO:0006915=PMID:14660608, GO:0005634=GO_REF:0000002, GO:0000122=PMID:9226370, GO:0045023=PMID:12101245, GO:0006461=PMID:10608892, GO:0008270=GO_REF:0000002, GO:0019899=PMID:19838211} Q5T0Y4 Protein Mdm4 protein 20130413 {GO:0005515=IPI, GO:0071157=IEA, GO:0043066=IEA, GO:0008284=IEA, GO:0008285=TAS, GO:0042177=IMP, GO:0008283=IEP, GO:0050821=IEP, GO:0071456=IEP, GO:0006915=IEP, GO:0005634=IEA, GO:0000122=IDA, GO:0045023=IEP, GO:0006461=IDA, GO:0008270=IEA, GO:0019899=IPI} G0 to G1 transition, apoptotic process, cell proliferation, cellular response to hypoxia, negative regulation of apoptotic process, negative regulation of cell cycle arrest, negative regulation of cell proliferation, negative regulation of protein catabolic process, negative regulation of transcription from RNA polymerase II promoter, positive regulation of cell proliferation, protein complex assembly, protein stabilization nucleus enzyme binding, protein binding, zinc ion binding Human InterPro:IPR016495 MDN1 GOC UniProtKB {GO:0006461=PMID:12102729, GO:0006200=PMID:12102729, GO:0005730=GO_REF:0000039, GO:0005634=PMID:12102729, GO:0051082=PMID:12102729, GO:0016887=PMID:12102729, GO:0005524=GO_REF:0000037} Q9NU22 Midasin protein 20130413 {GO:0006461=NAS, GO:0006200=NAS, GO:0005730=IEA, GO:0005634=NAS, GO:0051082=NAS, GO:0016887=NAS, GO:0005524=IEA} ATP catabolic process, protein complex assembly nucleolus, nucleus ATP binding, ATPase activity, unfolded protein binding Human MDP1 UniProtKB UniProtKB {GO:0004725=GO_REF:0000003, GO:0046872=GO_REF:0000037} Q86V88 Magnesium-dependent phosphatase 1 protein 20130413 {GO:0004725=IEA, GO:0046872=IEA} metal ion binding, protein tyrosine phosphatase activity Human EC:3.1.3.48 ME1 Reactome UniProtKB {GO:0050661=PMID:7622060, GO:0051262=GO_REF:0000019, GO:0030145=PMID:7622060, GO:0005975=PMID:8187880, GO:0004470=PMID:8187880, GO:0004473=PMID:8187880, GO:0006108=PMID:8187880, GO:0009055=PMID:7622060, GO:0044281=Reactome:REACT_111217, GO:0016619=GO_REF:0000002, GO:0046872=GO_REF:0000038, GO:0005829=Reactome:REACT_115847, GO:0005739=GO_REF:0000019, GO:0009743=PMID:8187880, GO:0006741=PMID:8187880, GO:0051287=PMID:7622060, GO:0043531=PMID:7622060, GO:0009725=GO_REF:0000024, GO:0044255=Reactome:REACT_22279} P48163 NADP-dependent malic enzyme protein 20130301 {GO:0050661=TAS, GO:0051262=IEA, GO:0030145=IDA, GO:0005975=NAS, GO:0004470=IDA, GO:0004473=IDA, GO:0006108=IDA, GO:0009055=TAS, GO:0044281=TAS, GO:0016619=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0009743=TAS, GO:0006741=TAS, GO:0051287=TAS, GO:0043531=TAS, GO:0009725=ISS, GO:0044255=TAS} NADP biosynthetic process, carbohydrate metabolic process, cellular lipid metabolic process, malate metabolic process, protein tetramerization, response to carbohydrate stimulus, response to hormone stimulus, small molecule metabolic process cytosol, mitochondrion ADP binding, NAD binding, NADP binding, electron carrier activity, malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity, malate dehydrogenase (oxaloacetate-decarboxylating) activity, malic enzyme activity, manganese ion binding, metal ion binding Human ME2 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0051287=GO_REF:0000002, GO:0005759=GO_REF:0000039, GO:0009055=PMID:1993674, GO:0006108=GO_REF:0000002, GO:0004471=PMID:1993674, GO:0016619=GO_REF:0000003, GO:0046872=GO_REF:0000037, GO:0043231=GO_REF:0000052} P23368 NAD-dependent malic enzyme, mitochondrial protein 20081203 {GO:0005739=IDA, GO:0051287=IEA, GO:0005759=IEA, GO:0009055=TAS, GO:0006108=IEA, GO:0004471=TAS, GO:0016619=IEA, GO:0046872=IEA, GO:0043231=IDA} malate metabolic process intracellular membrane-bounded organelle, mitochondrial matrix, mitochondrion NAD binding, electron carrier activity, malate dehydrogenase (decarboxylating) activity, malate dehydrogenase (oxaloacetate-decarboxylating) activity, metal ion binding Human ME3 UniProtKB UniProtKB {GO:0048037=PMID:7818469, GO:0072592=PMID:7818469, GO:0004470=PMID:7818469, GO:0004473=PMID:7818469, GO:0006108=GO_REF:0000002, GO:0016619=GO_REF:0000002, GO:0046872=GO_REF:0000038, GO:0016616=GO_REF:0000002, GO:0005739=PMID:7818469, GO:0009060=PMID:7818469, GO:0051287=GO_REF:0000002, GO:0006090=PMID:7818469, GO:0005759=GO_REF:0000039, GO:0055114=PMID:7818469} Q6TCH8 Malic enzyme protein 20130413 {GO:0048037=TAS, GO:0072592=TAS, GO:0004470=IDA, GO:0004473=IDA, GO:0006108=IEA, GO:0016619=IEA, GO:0046872=IEA, GO:0016616=IEA, GO:0005739=TAS, GO:0009060=TAS, GO:0051287=IEA, GO:0006090=IDA, GO:0005759=IEA, GO:0055114=IDA} aerobic respiration, malate metabolic process, oxidation-reduction process, oxygen metabolic process, pyruvate metabolic process mitochondrial matrix, mitochondrion NAD binding, cofactor binding, malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity, malate dehydrogenase (oxaloacetate-decarboxylating) activity, malic enzyme activity, metal ion binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Human UniProtKB-KW:KW-0479 MEA1 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0005737=GO_REF:0000019, GO:0007283=GO_REF:0000037, GO:0008584=PMID:2813404, GO:0030154=GO_REF:0000037} Q16626 Male-enhanced antigen 1 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0007283=IEA, GO:0008584=TAS, GO:0030154=IEA} cell differentiation, male gonad development, spermatogenesis cytoplasm protein binding Human UniProtKB:P63010 MEAF6 HPA UniProtKB {GO:0005515=PMID:19060904, GO:0005813=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0070776=PMID:18794358, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037, GO:0043981=PMID:16387653, GO:0005737=GO_REF:0000052, GO:0043983=PMID:16387653, GO:0043982=PMID:16387653, GO:0043984=PMID:16387653, GO:0043968=PMID:14966270, GO:0035267=PMID:14966270, GO:0044154=PMID:16387653} Q9HAF1 Chromatin modification-related protein MEAF6 protein 20111111 {GO:0005515=IPI, GO:0005813=IDA, GO:0006355=IEA, GO:0070776=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0006351=IEA, GO:0043981=IDA, GO:0005737=IDA, GO:0043983=IDA, GO:0043982=IDA, GO:0043984=IDA, GO:0043968=IDA, GO:0035267=IDA, GO:0044154=IDA} histone H2A acetylation, histone H3-K14 acetylation, histone H4-K12 acetylation, histone H4-K16 acetylation, histone H4-K5 acetylation, histone H4-K8 acetylation, regulation of transcription, DNA-dependent, transcription, DNA-dependent MOZ/MORF histone acetyltransferase complex, NuA4 histone acetyltransferase complex, centrosome, cytoplasm, nucleolus, nucleus protein binding Human MECOM GOC UniProtKB {GO:0005515=PMID:21555002, GO:0001780=GO_REF:0000019, GO:0003700=PMID:8643684, GO:0005634=PMID:15897867, GO:0009791=GO_REF:0000019, GO:0030154=GO_REF:0000037, GO:0043069=PMID:10856240, GO:0009617=GO_REF:0000019, GO:0046329=PMID:10856240, GO:0006954=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0051726=PMID:11568182, GO:0006355=PMID:8643684, GO:0006915=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000024, GO:0001701=GO_REF:0000019, GO:0060039=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0071425=GO_REF:0000024, GO:0009605=GO_REF:0000019, GO:0000118=PMID:11568182, GO:0016607=PMID:11568182, GO:0035116=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0072001=GO_REF:0000019, GO:0035115=GO_REF:0000019, GO:0030900=GO_REF:0000019, GO:0045893=PMID:11568182, GO:0045892=PMID:10856240} Q13465 MDS1 and EVI1 complex locus protein MDS1 protein 20130413 {GO:0005515=IPI, GO:0001780=IEA, GO:0003700=TAS, GO:0005634=IDA, GO:0009791=IEA, GO:0030154=IEA, GO:0043069=IMP, GO:0009617=IEA, GO:0046329=IMP, GO:0006954=IEA, GO:0045944=IEA, GO:0042127=IEA, GO:0051726=IDA, GO:0006355=TAS, GO:0006915=IEA, GO:0003676=IEA, GO:0003677=ISS, GO:0001701=IEA, GO:0060039=IEA, GO:0006351=IEA, GO:0071425=ISS, GO:0009605=IEA, GO:0000118=IDA, GO:0016607=IDA, GO:0035116=IEA, GO:0008270=IEA, GO:0072001=IEA, GO:0035115=IEA, GO:0030900=IEA, GO:0045893=IDA, GO:0045892=IDA} apoptotic process, cell differentiation, embryonic forelimb morphogenesis, embryonic hindlimb morphogenesis, forebrain development, hematopoietic stem cell proliferation, in utero embryonic development, inflammatory response, negative regulation of JNK cascade, negative regulation of programmed cell death, negative regulation of transcription, DNA-dependent, neutrophil homeostasis, pericardium development, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, post-embryonic development, regulation of cell cycle, regulation of cell proliferation, regulation of transcription, DNA-dependent, renal system development, response to bacterium, response to external stimulus, transcription, DNA-dependent histone deacetylase complex, nuclear speck, nucleus DNA binding, nucleic acid binding, protein binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human MECP2 HPA UniProtKB {GO:0005515=PMID:15696166, GO:0000792=PMID:11441023, GO:0003700=GO_REF:0000019, GO:0060291=GO_REF:0000019, GO:0009790=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0043524=GO_REF:0000019, GO:0006122=GO_REF:0000019, GO:0010385=PMID:17296936, GO:0001662=GO_REF:0000019, GO:0051965=GO_REF:0000019, GO:0007616=GO_REF:0000019, GO:0003714=PMID:10773092, GO:0019904=PMID:11441023, GO:0060079=GO_REF:0000019, GO:0021549=GO_REF:0000019, GO:0000122=PMID:9620804, GO:0007416=GO_REF:0000019, GO:0016358=GO_REF:0000019, GO:0008542=GO_REF:0000019, GO:0021591=GO_REF:0000019, GO:0035176=GO_REF:0000019, GO:0045893=GO_REF:0000019, GO:0045892=PMID:11441023, GO:0006541=GO_REF:0000019, GO:0008134=GO_REF:0000019, GO:0008344=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0006342=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0035067=GO_REF:0000019, GO:0003729=GO_REF:0000019, GO:0001964=GO_REF:0000019, GO:0002087=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0008104=GO_REF:0000019, GO:0032048=GO_REF:0000019, GO:0050432=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0006020=GO_REF:0000019, GO:0019230=GO_REF:0000019, GO:0016573=GO_REF:0000019, GO:0007585=GO_REF:0000019, GO:0042551=GO_REF:0000019, GO:0016571=GO_REF:0000019, GO:0003677=PMID:9620804, GO:0006351=GO_REF:0000037, GO:0019233=GO_REF:0000019, GO:0031061=GO_REF:0000019, GO:0047485=PMID:11441023, GO:0001976=GO_REF:0000019, GO:0035197=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0009405=GO_REF:0000019, GO:0006349=GO_REF:0000019, GO:0046470=GO_REF:0000019, GO:0008211=GO_REF:0000019} P51608 Methyl-CpG-binding protein 2 protein 20100326 {GO:0005515=IPI, GO:0000792=IDA, GO:0003700=IEA, GO:0060291=IEA, GO:0009790=IEA, GO:0009791=IEA, GO:0043524=IEA, GO:0006122=IEA, GO:0010385=IMP, GO:0001662=IEA, GO:0051965=IEA, GO:0007616=IEA, GO:0003714=TAS, GO:0019904=IPI, GO:0060079=IEA, GO:0021549=IEA, GO:0000122=TAS, GO:0007416=IEA, GO:0016358=IEA, GO:0008542=IEA, GO:0021591=IEA, GO:0035176=IEA, GO:0045893=IEA, GO:0045892=IDA, GO:0006541=IEA, GO:0008134=IEA, GO:0008344=IEA, GO:0008284=IEA, GO:0006342=IEA, GO:0005634=IDA, GO:0035067=IEA, GO:0003729=IEA, GO:0001964=IEA, GO:0002087=IEA, GO:0005737=IEA, GO:0008104=IEA, GO:0032048=IEA, GO:0050432=IEA, GO:0001666=IEA, GO:0006020=IEA, GO:0019230=IEA, GO:0016573=IEA, GO:0007585=IEA, GO:0042551=IEA, GO:0016571=IEA, GO:0003677=TAS, GO:0006351=IEA, GO:0019233=IEA, GO:0031061=IEA, GO:0047485=IPI, GO:0001976=IEA, GO:0035197=IEA, GO:0003682=IEA, GO:0009405=IEA, GO:0006349=IEA, GO:0046470=IEA, GO:0008211=IEA} adult locomotory behavior, behavioral fear response, cardiolipin metabolic process, catecholamine secretion, cerebellum development, chromatin silencing, dendrite development, embryo development, glucocorticoid metabolic process, glutamine metabolic process, histone acetylation, histone methylation, inositol metabolic process, long-term memory, long-term synaptic potentiation, mitochondrial electron transport, ubiquinol to cytochrome c, negative regulation of histone acetylation, negative regulation of histone methylation, negative regulation of neuron apoptotic process, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, neurological system process involved in regulation of systemic arterial blood pressure, neuron maturation, pathogenesis, phosphatidylcholine metabolic process, positive regulation of cell proliferation, positive regulation of synapse assembly, positive regulation of transcription, DNA-dependent, post-embryonic development, proprioception, protein localization, regulation of excitatory postsynaptic membrane potential, regulation of gene expression by genetic imprinting, regulation of respiratory gaseous exchange by neurological system process, respiratory gaseous exchange, response to hypoxia, sensory perception of pain, social behavior, startle response, synapse assembly, transcription, DNA-dependent, ventricular system development, visual learning cytoplasm, heterochromatin, nucleus DNA binding, chromatin binding, double-stranded methylated DNA binding, mRNA binding, protein N-terminus binding, protein binding, protein domain specific binding, sequence-specific DNA binding transcription factor activity, siRNA binding, transcription corepressor activity, transcription factor binding Human MECR HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0019166=PMID:12654921, GO:0006631=PMID:12654921, GO:0016491=GO_REF:0000002, GO:0006633=GO_REF:0000037, GO:0008270=GO_REF:0000002} Q9BV79 Trans-2-enoyl-CoA reductase, mitochondrial protein 20111111 {GO:0005739=IDA, GO:0019166=IDA, GO:0006631=IDA, GO:0016491=IEA, GO:0006633=IEA, GO:0008270=IEA} fatty acid biosynthetic process, fatty acid metabolic process mitochondrion oxidoreductase activity, trans-2-enoyl-CoA reductase (NADPH) activity, zinc ion binding Human MED1 IntAct UniProtKB {GO:0005515=PMID:19377461, GO:0010839=PMID:17223341, GO:0010467=Reactome:REACT_71, GO:0033160=GO_REF:0000019, GO:0006367=Reactome:REACT_15525, GO:0006702=PMID:19497978, GO:0000981=GO_REF:0000024, GO:0060750=GO_REF:0000019, GO:0060335=GO_REF:0000019, GO:0045618=PMID:17082781, GO:0042809=PMID:17223341, GO:0045444=PMID:12037571, GO:0042789=GO_REF:0000024, GO:0006590=GO_REF:0000019, GO:0070371=PMID:18391015, GO:0044255=Reactome:REACT_22279, GO:0003406=GO_REF:0000019, GO:0003712=PMID:12218053, GO:0016922=PMID:18391015, GO:0001104=PMID:10198638, GO:0003713=PMID:12037571, GO:0030331=PMID:9653119, GO:0001892=GO_REF:0000019, GO:0000122=GO_REF:0000024, GO:0001889=GO_REF:0000019, GO:0035855=GO_REF:0000024, GO:0007420=GO_REF:0000019, GO:0071383=PMID:18391015, GO:0016592=PMID:14638676, GO:0005654=Reactome:REACT_19207, GO:0033148=GO_REF:0000019, GO:0045893=PMID:10198638, GO:0008134=PMID:17641689, GO:0097067=PMID:18391015, GO:0031100=GO_REF:0000019, GO:0035357=GO_REF:0000019, GO:0005634=PMID:16314496, GO:0044281=Reactome:REACT_111217, GO:0042974=PMID:9653119, GO:2000273=PMID:18391015, GO:0042975=PMID:9653119, GO:0030375=PMID:18391015, GO:0046966=PMID:9653119, GO:0030374=PMID:17641689, GO:0030518=PMID:11867769, GO:0002088=GO_REF:0000024, GO:0048822=GO_REF:0000019, GO:0045944=PMID:12037571, GO:0048821=GO_REF:0000024, GO:0035729=GO_REF:0000019, GO:0003222=GO_REF:0000019, GO:0051726=PMID:16314496, GO:0030224=GO_REF:0000019, GO:0004872=PMID:12218053, GO:2001141=PMID:17223341, GO:0035162=GO_REF:0000019, GO:0002154=PMID:16314496, GO:0043066=GO_REF:0000024, GO:0060745=GO_REF:0000019, GO:0060744=GO_REF:0000019, GO:0035050=GO_REF:0000019, GO:0006356=PMID:16314496, GO:0070318=GO_REF:0000019, GO:2000347=GO_REF:0000019, GO:0001525=GO_REF:0000024, GO:0050693=PMID:17827210, GO:0070562=GO_REF:0000019, GO:0006260=GO_REF:0000019, GO:0045665=GO_REF:0000024, GO:0007595=GO_REF:0000019, GO:0071364=PMID:16314496, GO:0030216=PMID:17223341, GO:0003682=PMID:17641689, GO:0035116=GO_REF:0000019, GO:0033601=GO_REF:0000019, GO:0030521=PMID:12218053} Q15648 Mediator of RNA polymerase II transcription subunit 1 protein 20130415 {GO:0005515=IPI, GO:0010839=IMP, GO:0010467=TAS, GO:0033160=IEA, GO:0006367=TAS, GO:0006702=IMP, GO:0000981=ISS, GO:0060750=IEA, GO:0060335=IEA, GO:0045618=IMP, GO:0042809=TAS, GO:0045444=IDA, GO:0042789=ISS, GO:0006590=IEA, GO:0070371=IDA, GO:0044255=TAS, GO:0003406=IEA, GO:0003712=IDA, GO:0016922=IDA, GO:0001104=IDA, GO:0003713=IDA, GO:0030331=IPI, GO:0001892=IEA, GO:0000122=ISS, GO:0001889=IEA, GO:0035855=ISS, GO:0007420=IEA, GO:0071383=IDA, GO:0016592=IDA, GO:0005654=TAS, GO:0033148=IEA, GO:0045893=IDA, GO:0008134=IPI, GO:0097067=IDA, GO:0031100=IEA, GO:0035357=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0042974=IPI, GO:2000273=IMP, GO:0042975=IPI, GO:0030375=IMP, GO:0046966=IPI, GO:0030374=IMP, GO:0030518=IDA, GO:0002088=ISS, GO:0048822=IEA, GO:0045944=IDA, GO:0048821=ISS, GO:0035729=IEA, GO:0003222=IEA, GO:0051726=NAS, GO:0030224=IEA, GO:0004872=IDA, GO:2001141=IMP, GO:0035162=IEA, GO:0002154=IMP, GO:0043066=ISS, GO:0060745=IEA, GO:0060744=IEA, GO:0035050=IEA, GO:0006356=IDA, GO:0070318=IEA, GO:2000347=IEA, GO:0001525=ISS, GO:0050693=IPI, GO:0070562=IEA, GO:0006260=IEA, GO:0045665=ISS, GO:0007595=IEA, GO:0071364=IDA, GO:0030216=IMP, GO:0003682=IMP, GO:0035116=IEA, GO:0033601=IEA, GO:0030521=IDA} DNA replication, ERK1 and ERK2 cascade, androgen biosynthetic process, androgen receptor signaling pathway, angiogenesis, brain development, cellular lipid metabolic process, cellular response to epidermal growth factor stimulus, cellular response to hepatocyte growth factor stimulus, cellular response to steroid hormone stimulus, cellular response to thyroid hormone stimulus, embryonic heart tube development, embryonic hemopoiesis, embryonic hindlimb morphogenesis, embryonic placenta development, enucleate erythrocyte development, epithelial cell proliferation involved in mammary gland duct elongation, erythrocyte development, fat cell differentiation, gene expression, intracellular steroid hormone receptor signaling pathway, keratinocyte differentiation, lactation, lens development in camera-type eye, liver development, mRNA transcription from RNA polymerase II promoter, mammary gland branching involved in pregnancy, mammary gland branching involved in thelarche, megakaryocyte development, monocyte differentiation, negative regulation of apoptotic process, negative regulation of keratinocyte proliferation, negative regulation of neuron differentiation, negative regulation of transcription from RNA polymerase II promoter, organ regeneration, peroxisome proliferator activated receptor signaling pathway, positive regulation of G0 to G1 transition, positive regulation of hepatocyte proliferation, positive regulation of interferon-gamma-mediated signaling pathway, positive regulation of intracellular estrogen receptor signaling pathway, positive regulation of keratinocyte differentiation, positive regulation of mammary gland epithelial cell proliferation, positive regulation of protein import into nucleus, translocation, positive regulation of receptor activity, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of RNA biosynthetic process, regulation of cell cycle, regulation of transcription from RNA polymerase I promoter, regulation of vitamin D receptor signaling pathway, retinal pigment epithelium development, small molecule metabolic process, thyroid hormone generation, thyroid hormone mediated signaling pathway, transcription initiation from RNA polymerase II promoter, ventricular trabecula myocardium morphogenesis mediator complex, nucleoplasm, nucleus LBD domain binding, RNA polymerase II transcription cofactor activity, chromatin binding, estrogen receptor binding, ligand-dependent nuclear receptor binding, ligand-dependent nuclear receptor transcription coactivator activity, peroxisome proliferator activated receptor binding, protein binding, receptor activity, retinoic acid receptor binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, thyroid hormone receptor binding, thyroid hormone receptor coactivator activity, transcription coactivator activity, transcription cofactor activity, transcription factor binding, vitamin D receptor binding Human UniProtKB:P10276 MED10 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_12627, GO:0001104=GO_REF:0000002, GO:0045944=GO_REF:0000019, GO:0019827=GO_REF:0000019, GO:0016592=GO_REF:0000019, GO:0005654=Reactome:REACT_12480} Q9BTT4 Mediator of RNA polymerase II transcription subunit 10 protein 20130213 {GO:0010467=TAS, GO:0006367=TAS, GO:0001104=IEA, GO:0045944=IEA, GO:0019827=IEA, GO:0016592=IEA, GO:0005654=TAS} gene expression, positive regulation of transcription from RNA polymerase II promoter, stem cell maintenance, transcription initiation from RNA polymerase II promoter mediator complex, nucleoplasm RNA polymerase II transcription cofactor activity Human MED11 IntAct UniProtKB {GO:0005515=PMID:12584197, GO:0001104=GO_REF:0000002, GO:0016592=PMID:14638676} Q9P086 Mediator of RNA polymerase II transcription subunit 11 protein 20130415 {GO:0005515=IPI, GO:0001104=IEA, GO:0016592=IDA} mediator complex RNA polymerase II transcription cofactor activity, protein binding Human UniProtKB:Q15528 MED12 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_12627, GO:0008013=GO_REF:0000002, GO:0030178=PMID:17000779, GO:0005634=PMID:17000779, GO:0090245=GO_REF:0000019, GO:0007507=GO_REF:0000019, GO:0046966=PMID:10198638, GO:0030374=PMID:10235266, GO:0030518=PMID:11867769, GO:0042809=PMID:10235266, GO:0045944=PMID:12037571, GO:0004872=PMID:12218053, GO:0060070=GO_REF:0000019, GO:0060071=GO_REF:0000019, GO:0003712=PMID:12218053, GO:0001104=PMID:10198638, GO:0019904=PMID:11984006, GO:0003713=PMID:12037571, GO:0001843=GO_REF:0000019, GO:0008022=PMID:17000779, GO:0016592=PMID:12037571, GO:0019827=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0005654=Reactome:REACT_12480, GO:0045893=PMID:10198638, GO:0030521=PMID:12218053} Q93074 Mediator of RNA polymerase II transcription subunit 12 protein 20130213 {GO:0010467=TAS, GO:0006367=TAS, GO:0008013=IEA, GO:0030178=IMP, GO:0005634=IDA, GO:0090245=IEA, GO:0007507=IEA, GO:0046966=IDA, GO:0030374=NAS, GO:0030518=IDA, GO:0042809=NAS, GO:0045944=IDA, GO:0004872=IDA, GO:0060070=IEA, GO:0060071=IEA, GO:0003712=IDA, GO:0001104=IDA, GO:0019904=IPI, GO:0003713=IDA, GO:0001843=IEA, GO:0008022=IPI, GO:0016592=IDA, GO:0019827=IEA, GO:0003682=IEA, GO:0005654=TAS, GO:0045893=IDA, GO:0030521=IDA} Wnt receptor signaling pathway, planar cell polarity pathway, androgen receptor signaling pathway, axis elongation involved in somitogenesis, canonical Wnt receptor signaling pathway, gene expression, heart development, intracellular steroid hormone receptor signaling pathway, negative regulation of Wnt receptor signaling pathway, neural tube closure, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, stem cell maintenance, transcription initiation from RNA polymerase II promoter mediator complex, nucleoplasm, nucleus RNA polymerase II transcription cofactor activity, beta-catenin binding, chromatin binding, ligand-dependent nuclear receptor transcription coactivator activity, protein C-terminus binding, protein domain specific binding, receptor activity, thyroid hormone receptor binding, transcription coactivator activity, transcription cofactor activity, vitamin D receptor binding Human MED12L InterPro UniProtKB {GO:0001104=GO_REF:0000002, GO:0008013=GO_REF:0000002, GO:0016592=GO_REF:0000002} Q86YW9 Mediator of RNA polymerase II transcription subunit 12-like protein protein 20130413 {GO:0001104=IEA, GO:0008013=IEA, GO:0016592=IEA} mediator complex RNA polymerase II transcription cofactor activity, beta-catenin binding Human InterPro:IPR019035|InterPro:IPR021989 MED13 Reactome UniProtKB {GO:0003712=PMID:12218053, GO:0010467=Reactome:REACT_71, GO:0001104=PMID:10198638, GO:0006367=Reactome:REACT_12627, GO:0003713=PMID:12037571, GO:0005634=PMID:10235267, GO:0046966=PMID:10198638, GO:0030374=PMID:10235266, GO:0030518=PMID:11867769, GO:0042809=PMID:10235266, GO:0045944=PMID:12037571, GO:0016592=PMID:12037571, GO:0005654=Reactome:REACT_12480, GO:0004872=PMID:12218053, GO:0045893=PMID:10198638, GO:0030521=PMID:12218053} Q9UHV7 Mediator of RNA polymerase II transcription subunit 13 protein 20130213 {GO:0003712=IDA, GO:0010467=TAS, GO:0001104=IDA, GO:0006367=TAS, GO:0003713=IDA, GO:0005634=IDA, GO:0046966=IDA, GO:0030374=NAS, GO:0030518=IDA, GO:0042809=NAS, GO:0045944=IDA, GO:0016592=IDA, GO:0005654=TAS, GO:0004872=IDA, GO:0045893=IDA, GO:0030521=IDA} androgen receptor signaling pathway, gene expression, intracellular steroid hormone receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, transcription initiation from RNA polymerase II promoter mediator complex, nucleoplasm, nucleus RNA polymerase II transcription cofactor activity, ligand-dependent nuclear receptor transcription coactivator activity, receptor activity, thyroid hormone receptor binding, transcription coactivator activity, transcription cofactor activity, vitamin D receptor binding Human MED13L ENSEMBL UniProtKB {GO:0001104=GO_REF:0000002, GO:0016592=GO_REF:0000019} Q71F56 Mediator of RNA polymerase II transcription subunit 13-like protein 20130413 {GO:0001104=IEA, GO:0016592=IEA} mediator complex RNA polymerase II transcription cofactor activity Human Ensembl:ENSMUSP00000098379 MED14 Reactome UniProtKB {GO:0003712=PMID:12218053, GO:0010467=Reactome:REACT_71, GO:0001104=PMID:10198638, GO:0006367=Reactome:REACT_12627, GO:0006357=PMID:9989412, GO:0003713=PMID:12037571, GO:0005634=PMID:10235267, GO:0046966=PMID:10198638, GO:0030374=PMID:10235266, GO:0030518=PMID:11867769, GO:0042809=PMID:10235266, GO:0019827=GO_REF:0000019, GO:0016592=PMID:12037571, GO:0045944=PMID:12037571, GO:0005654=Reactome:REACT_12480, GO:0004872=PMID:12218053, GO:0045893=PMID:10198638, GO:0030521=PMID:12218053} O60244 Mediator of RNA polymerase II transcription subunit 14 protein 20130213 {GO:0003712=IDA, GO:0010467=TAS, GO:0001104=IDA, GO:0006367=TAS, GO:0006357=TAS, GO:0003713=IDA, GO:0005634=IDA, GO:0046966=IDA, GO:0030374=NAS, GO:0030518=IDA, GO:0042809=NAS, GO:0019827=IEA, GO:0016592=IDA, GO:0045944=IDA, GO:0005654=TAS, GO:0004872=IDA, GO:0045893=IDA, GO:0030521=IDA} androgen receptor signaling pathway, gene expression, intracellular steroid hormone receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, stem cell maintenance, transcription initiation from RNA polymerase II promoter mediator complex, nucleoplasm, nucleus RNA polymerase II transcription cofactor activity, ligand-dependent nuclear receptor transcription coactivator activity, receptor activity, thyroid hormone receptor binding, transcription coactivator activity, transcription cofactor activity, vitamin D receptor binding Human MED15 HPA UniProtKB {GO:0005515=PMID:16799563, GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_12627, GO:0005794=GO_REF:0000052, GO:0001104=GO_REF:0000002, GO:0019827=GO_REF:0000019, GO:0016592=GO_REF:0000002, GO:0005654=Reactome:REACT_12480, GO:0005634=GO_REF:0000052} Q96RN5 Mediator of RNA polymerase II transcription subunit 15 protein 20101115 {GO:0005515=IPI, GO:0010467=TAS, GO:0006367=TAS, GO:0005794=IDA, GO:0001104=IEA, GO:0019827=IEA, GO:0016592=IEA, GO:0005654=TAS, GO:0005634=IDA} gene expression, stem cell maintenance, transcription initiation from RNA polymerase II promoter Golgi apparatus, mediator complex, nucleoplasm, nucleus RNA polymerase II transcription cofactor activity, protein binding Human MED16 Reactome UniProtKB {GO:0003712=PMID:12218053, GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_12627, GO:0006366=PMID:10198638, GO:0006357=PMID:10198638, GO:0003713=PMID:10198638, GO:0005634=PMID:10198638, GO:0030375=PMID:10198638, GO:0046966=PMID:10198638, GO:0030518=PMID:11867769, GO:0042809=PMID:10235266, GO:0016592=PMID:10198638, GO:0005654=Reactome:REACT_12480, GO:0004872=PMID:12218053, GO:0045893=PMID:10198638, GO:0030521=PMID:12218053} Q9Y2X0 Mediator of RNA polymerase II transcription subunit 16 protein 20111222 {GO:0003712=IDA, GO:0010467=TAS, GO:0006367=TAS, GO:0006366=TAS, GO:0006357=NAS, GO:0003713=TAS, GO:0005634=NAS, GO:0030375=IDA, GO:0046966=IDA, GO:0030518=IDA, GO:0042809=NAS, GO:0016592=IDA, GO:0005654=TAS, GO:0004872=IDA, GO:0045893=IDA, GO:0030521=IDA} androgen receptor signaling pathway, gene expression, intracellular steroid hormone receptor signaling pathway, positive regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter mediator complex, nucleoplasm, nucleus receptor activity, thyroid hormone receptor binding, thyroid hormone receptor coactivator activity, transcription coactivator activity, transcription cofactor activity, vitamin D receptor binding Human MED17 Reactome UniProtKB {GO:0003712=PMID:12218053, GO:0010467=Reactome:REACT_71, GO:0005667=PMID:9989412, GO:0001104=PMID:10198638, GO:0006367=Reactome:REACT_12627, GO:0006357=PMID:9989412, GO:0003713=PMID:12037571, GO:0005634=PMID:10235267, GO:0046966=PMID:10198638, GO:0030374=PMID:10235266, GO:0030518=PMID:11867769, GO:0042809=PMID:10235266, GO:0019827=GO_REF:0000019, GO:0045944=PMID:12037571, GO:0016592=PMID:14638676, GO:0005654=Reactome:REACT_12480, GO:0004872=PMID:12218053, GO:0045893=PMID:10198638, GO:0030521=PMID:12218053} Q9NVC6 Mediator of RNA polymerase II transcription subunit 17 protein 20130213 {GO:0003712=IDA, GO:0010467=TAS, GO:0005667=IDA, GO:0001104=IDA, GO:0006367=TAS, GO:0006357=IDA, GO:0003713=IDA, GO:0005634=IDA, GO:0046966=IDA, GO:0030374=NAS, GO:0030518=IDA, GO:0042809=NAS, GO:0019827=IEA, GO:0045944=IDA, GO:0016592=IDA, GO:0005654=TAS, GO:0004872=IDA, GO:0045893=IDA, GO:0030521=IDA} androgen receptor signaling pathway, gene expression, intracellular steroid hormone receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, stem cell maintenance, transcription initiation from RNA polymerase II promoter mediator complex, nucleoplasm, nucleus, transcription factor complex RNA polymerase II transcription cofactor activity, ligand-dependent nuclear receptor transcription coactivator activity, receptor activity, thyroid hormone receptor binding, transcription coactivator activity, transcription cofactor activity, vitamin D receptor binding Human MED18 IntAct UniProtKB {GO:0005515=PMID:12584197, GO:0001104=GO_REF:0000002, GO:0016592=PMID:14638676} Q9BUE0 Mediator of RNA polymerase II transcription subunit 18 protein 20130415 {GO:0005515=IPI, GO:0001104=IEA, GO:0016592=IDA} mediator complex RNA polymerase II transcription cofactor activity, protein binding Human UniProtKB:Q9R0X0 MED19 InterPro UniProtKB {GO:0001104=GO_REF:0000002, GO:0016592=GO_REF:0000002, GO:0005634=GO_REF:0000052} J3KR33 Mediator of RNA polymerase II transcription subunit 19 protein 20130413 {GO:0001104=IEA, GO:0016592=IEA, GO:0005634=IDA} mediator complex, nucleus RNA polymerase II transcription cofactor activity Human InterPro:IPR019403 MED20 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_12627, GO:0001104=GO_REF:0000002, GO:0006357=PMID:9933582, GO:0006366=PMID:9933582, GO:0003899=PMID:9933582, GO:0016592=PMID:9933582, GO:0005654=Reactome:REACT_12410, GO:0006351=PMID:9933582} Q9H944 Mediator of RNA polymerase II transcription subunit 20 protein 20130213 {GO:0010467=TAS, GO:0006367=TAS, GO:0001104=IEA, GO:0006357=TAS, GO:0006366=TAS, GO:0003899=NAS, GO:0016592=NAS, GO:0005654=TAS, GO:0006351=NAS} gene expression, regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent mediator complex, nucleoplasm DNA-directed RNA polymerase activity, RNA polymerase II transcription cofactor activity Human MED21 PINC UniProtKB {GO:0006357=PMID:8598913, GO:0003899=PMID:8598913, GO:0045944=PMID:12037571, GO:0016592=PMID:12037571, GO:0019827=GO_REF:0000019, GO:0003713=PMID:12037571, GO:0001824=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q13503 Mediator of RNA polymerase II transcription subunit 21 protein 20030904 {GO:0006357=TAS, GO:0003899=TAS, GO:0045944=IDA, GO:0016592=IDA, GO:0019827=IEA, GO:0003713=IDA, GO:0001824=IEA, GO:0006351=IEA} blastocyst development, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, stem cell maintenance, transcription, DNA-dependent mediator complex DNA-directed RNA polymerase activity, transcription coactivator activity Human MED22 InterPro UniProtKB {GO:0005515=PMID:12584197, GO:0005737=PMID:8586415, GO:0001104=GO_REF:0000002, GO:0016592=GO_REF:0000002} Q5T8T8 Mediator complex subunit 22 protein 20130413 {GO:0005515=IPI, GO:0005737=TAS, GO:0001104=IEA, GO:0016592=IEA} cytoplasm, mediator complex RNA polymerase II transcription cofactor activity, protein binding Human InterPro:IPR009332 MED23 Reactome UniProtKB {GO:0005515=PMID:17438371, GO:0010467=Reactome:REACT_71, GO:0005667=PMID:9989412, GO:0006355=PMID:9989412, GO:0006367=Reactome:REACT_12627, GO:0006357=PMID:9989412, GO:0016592=GO_REF:0000019, GO:0003713=PMID:9989412, GO:0005654=Reactome:REACT_12480} Q9ULK4 Mediator of RNA polymerase II transcription subunit 23 protein 20111222 {GO:0005515=IPI, GO:0010467=TAS, GO:0005667=IDA, GO:0006355=IDA, GO:0006367=TAS, GO:0006357=TAS, GO:0016592=IEA, GO:0003713=TAS, GO:0005654=TAS} gene expression, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription initiation from RNA polymerase II promoter mediator complex, nucleoplasm, transcription factor complex protein binding, transcription coactivator activity Human MED24 Reactome UniProtKB {GO:0003712=PMID:12218053, GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000029, GO:0001104=PMID:10198638, GO:0006367=Reactome:REACT_12627, GO:0006366=GO_REF:0000019, GO:0003713=GO_REF:0000019, GO:0005634=PMID:10235267, GO:0051291=GO_REF:0000019, GO:0046966=PMID:10198638, GO:0030374=PMID:10235266, GO:0030518=PMID:11867769, GO:0042809=PMID:10235266, GO:0016592=PMID:9653119, GO:0019827=GO_REF:0000019, GO:0005654=Reactome:REACT_12480, GO:0004872=PMID:12218053, GO:0045893=PMID:10198638, GO:0004402=GO_REF:0000019, GO:0030521=PMID:12218053} O75448 Mediator of RNA polymerase II transcription subunit 24 protein 20130213 {GO:0003712=IDA, GO:0010467=TAS, GO:0006355=NAS, GO:0001104=IDA, GO:0006367=TAS, GO:0006366=IEA, GO:0003713=IEA, GO:0005634=IDA, GO:0051291=IEA, GO:0046966=IDA, GO:0030374=NAS, GO:0030518=IDA, GO:0042809=NAS, GO:0016592=NAS, GO:0019827=IEA, GO:0005654=TAS, GO:0004872=IDA, GO:0045893=IDA, GO:0004402=IEA, GO:0030521=IDA} androgen receptor signaling pathway, gene expression, intracellular steroid hormone receptor signaling pathway, positive regulation of transcription, DNA-dependent, protein heterooligomerization, regulation of transcription, DNA-dependent, stem cell maintenance, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter mediator complex, nucleoplasm, nucleus RNA polymerase II transcription cofactor activity, histone acetyltransferase activity, ligand-dependent nuclear receptor transcription coactivator activity, receptor activity, thyroid hormone receptor binding, transcription coactivator activity, transcription cofactor activity, vitamin D receptor binding Human MED25 Reactome UniProtKB {GO:0005515=PMID:17641689, GO:0010467=Reactome:REACT_71, GO:0046965=PMID:17641689, GO:0006367=Reactome:REACT_12627, GO:0048147=PMID:17641689, GO:0005654=Reactome:REACT_12480, GO:0042974=PMID:17641689, GO:0035563=PMID:17641689, GO:0071158=PMID:17641689, GO:0008134=PMID:17641689} Q71SY5 Mediator of RNA polymerase II transcription subunit 25 protein 20130213 {GO:0005515=IPI, GO:0010467=TAS, GO:0046965=IPI, GO:0006367=TAS, GO:0048147=IMP, GO:0005654=TAS, GO:0042974=IPI, GO:0035563=IMP, GO:0071158=IMP, GO:0008134=IPI} gene expression, negative regulation of fibroblast proliferation, positive regulation of cell cycle arrest, positive regulation of chromatin binding, transcription initiation from RNA polymerase II promoter nucleoplasm protein binding, retinoic acid receptor binding, retinoid X receptor binding, transcription factor binding Human MED26 IntAct UniProtKB {GO:0005515=PMID:21729782, GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_12627, GO:0001104=PMID:15989967, GO:0006357=PMID:15989967, GO:0016592=PMID:15989967, GO:0003713=PMID:9989412, GO:0005654=Reactome:REACT_12480, GO:0005634=GO_REF:0000002, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000002} O95402 Mediator of RNA polymerase II transcription subunit 26 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0006367=TAS, GO:0001104=IDA, GO:0006357=IDA, GO:0016592=IDA, GO:0003713=TAS, GO:0005654=TAS, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} gene expression, regulation of transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent mediator complex, nucleoplasm, nucleus DNA binding, RNA polymerase II transcription cofactor activity, protein binding, transcription coactivator activity Human UniProtKB:Q96JC9 MED27 HPA UniProtKB {GO:0010467=Reactome:REACT_71, GO:0005667=PMID:9989412, GO:0005737=GO_REF:0000052, GO:0006367=Reactome:REACT_12627, GO:0006357=PMID:9989412, GO:0019827=GO_REF:0000019, GO:0016592=GO_REF:0000019, GO:0003713=PMID:10882111, GO:0005730=GO_REF:0000052, GO:0005654=Reactome:REACT_12410, GO:0005634=GO_REF:0000052} Q6P2C8 Mediator of RNA polymerase II transcription subunit 27 protein 20101115 {GO:0010467=TAS, GO:0005667=IDA, GO:0005737=IDA, GO:0006367=TAS, GO:0006357=IDA, GO:0019827=IEA, GO:0016592=IEA, GO:0003713=IDA, GO:0005730=IDA, GO:0005654=TAS, GO:0005634=IDA} gene expression, regulation of transcription from RNA polymerase II promoter, stem cell maintenance, transcription initiation from RNA polymerase II promoter cytoplasm, mediator complex, nucleolus, nucleoplasm, nucleus, transcription factor complex transcription coactivator activity Human MED28 HPA UniProtKB {GO:0005515=PMID:16899217, GO:0006355=GO_REF:0000037, GO:0016020=GO_REF:0000039, GO:0051151=GO_REF:0000019, GO:0019827=GO_REF:0000019, GO:0016592=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0003779=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0030864=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q9H204 Mediator of RNA polymerase II transcription subunit 28 protein 20110516 {GO:0005515=IPI, GO:0006355=IEA, GO:0016020=IEA, GO:0051151=IEA, GO:0019827=IEA, GO:0016592=IEA, GO:0005730=IDA, GO:0003779=IEA, GO:0005634=IDA, GO:0030864=IEA, GO:0006351=IEA} negative regulation of smooth muscle cell differentiation, regulation of transcription, DNA-dependent, stem cell maintenance, transcription, DNA-dependent cortical actin cytoskeleton, mediator complex, membrane, nucleolus, nucleus actin binding, protein binding NOT Human MED29 MGI UniProtKB {GO:0006355=GO_REF:0000037, GO:0016592=PMID:14638676, GO:0006351=GO_REF:0000037} Q9NX70 Mediator of RNA polymerase II transcription subunit 29 protein 20091109 {GO:0006355=IEA, GO:0016592=IDA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent mediator complex Human MED30 Reactome UniProtKB {GO:0005515=PMID:21784977, GO:0003712=PMID:12218053, GO:0010467=Reactome:REACT_71, GO:0001104=PMID:10198638, GO:0006367=Reactome:REACT_12627, GO:0005634=PMID:10235267, GO:0046966=PMID:10198638, GO:0030374=PMID:10235266, GO:0030518=PMID:11867769, GO:0042809=PMID:10235266, GO:0019827=GO_REF:0000019, GO:0016592=PMID:10198638, GO:0005654=Reactome:REACT_12410, GO:0004872=PMID:12218053, GO:0045893=PMID:10198638, GO:0030521=PMID:12218053} Q96HR3 Mediator of RNA polymerase II transcription subunit 30 protein 20130213 {GO:0005515=IPI, GO:0003712=IDA, GO:0010467=TAS, GO:0001104=IDA, GO:0006367=TAS, GO:0005634=IDA, GO:0046966=IDA, GO:0030374=NAS, GO:0030518=IDA, GO:0042809=NAS, GO:0019827=IEA, GO:0016592=IDA, GO:0005654=TAS, GO:0004872=IDA, GO:0045893=IDA, GO:0030521=IDA} androgen receptor signaling pathway, gene expression, intracellular steroid hormone receptor signaling pathway, positive regulation of transcription, DNA-dependent, stem cell maintenance, transcription initiation from RNA polymerase II promoter mediator complex, nucleoplasm, nucleus RNA polymerase II transcription cofactor activity, ligand-dependent nuclear receptor transcription coactivator activity, protein binding, receptor activity, thyroid hormone receptor binding, transcription cofactor activity, vitamin D receptor binding Human MED31 IntAct UniProtKB {GO:0005515=PMID:15383276, GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_12627, GO:0006461=GO_REF:0000019, GO:0001104=GO_REF:0000002, GO:0016592=GO_REF:0000002, GO:0005654=Reactome:REACT_12410, GO:0032403=GO_REF:0000019} Q9Y3C7 Mediator of RNA polymerase II transcription subunit 31 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0006367=TAS, GO:0006461=IEA, GO:0001104=IEA, GO:0016592=IEA, GO:0005654=TAS, GO:0032403=IEA} gene expression, protein complex assembly, transcription initiation from RNA polymerase II promoter mediator complex, nucleoplasm RNA polymerase II transcription cofactor activity, protein binding, protein complex binding Human UniProtKB:P42858 MED4 HPA UniProtKB {GO:0003712=PMID:12218053, GO:0005515=PMID:17438371, GO:0010467=Reactome:REACT_71, GO:0001104=PMID:10882111, GO:0006367=Reactome:REACT_12627, GO:0006366=PMID:10882111, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0046966=PMID:10198638, GO:0030374=PMID:10235266, GO:0030518=PMID:11867769, GO:0042809=PMID:10235266, GO:0016592=PMID:14638676, GO:0005654=Reactome:REACT_12480, GO:0004872=PMID:12218053, GO:0045893=PMID:10198638, GO:0030521=PMID:12218053} Q9NPJ6 Mediator of RNA polymerase II transcription subunit 4 protein 20101115 {GO:0003712=IDA, GO:0005515=IPI, GO:0010467=TAS, GO:0001104=IDA, GO:0006367=TAS, GO:0006366=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0046966=IDA, GO:0030374=NAS, GO:0030518=IDA, GO:0042809=NAS, GO:0016592=IDA, GO:0005654=TAS, GO:0004872=IDA, GO:0045893=IDA, GO:0030521=IDA} androgen receptor signaling pathway, gene expression, intracellular steroid hormone receptor signaling pathway, positive regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter mediator complex, nucleolus, nucleoplasm, nucleus RNA polymerase II transcription cofactor activity, ligand-dependent nuclear receptor transcription coactivator activity, protein binding, receptor activity, thyroid hormone receptor binding, transcription cofactor activity, vitamin D receptor binding NOT Human MED6 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_12627, GO:0001104=GO_REF:0000002, GO:0006357=PMID:10024883, GO:0045944=PMID:12037571, GO:0019827=GO_REF:0000019, GO:0016592=PMID:14638676, GO:0003713=PMID:12037571, GO:0005654=Reactome:REACT_12480, GO:0005634=PMID:10024883, GO:0003677=GO_REF:0000019, GO:0008134=PMID:17641689} O75586 Mediator of RNA polymerase II transcription subunit 6 protein 20130213 {GO:0010467=TAS, GO:0006367=TAS, GO:0001104=IEA, GO:0006357=TAS, GO:0045944=IDA, GO:0019827=IEA, GO:0016592=IDA, GO:0003713=IDA, GO:0005654=TAS, GO:0005634=TAS, GO:0003677=IEA, GO:0008134=IPI} gene expression, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, stem cell maintenance, transcription initiation from RNA polymerase II promoter mediator complex, nucleoplasm, nucleus DNA binding, RNA polymerase II transcription cofactor activity, transcription coactivator activity, transcription factor binding Human MED7 Reactome UniProtKB {GO:0005515=PMID:18391015, GO:0010467=Reactome:REACT_71, GO:0005667=PMID:9989412, GO:0006367=Reactome:REACT_12627, GO:0001104=GO_REF:0000002, GO:0006357=PMID:9989412, GO:0019827=GO_REF:0000019, GO:0016592=GO_REF:0000019, GO:0003713=PMID:9989412, GO:0005654=Reactome:REACT_12480} O43513 Mediator of RNA polymerase II transcription subunit 7 protein 20130213 {GO:0005515=IPI, GO:0010467=TAS, GO:0005667=IDA, GO:0006367=TAS, GO:0001104=IEA, GO:0006357=IDA, GO:0019827=IEA, GO:0016592=IEA, GO:0003713=TAS, GO:0005654=TAS} gene expression, regulation of transcription from RNA polymerase II promoter, stem cell maintenance, transcription initiation from RNA polymerase II promoter mediator complex, nucleoplasm, transcription factor complex RNA polymerase II transcription cofactor activity, protein binding, transcription coactivator activity Human MED8 IntAct UniProtKB {GO:0005515=PMID:12149480, GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_12627, GO:0016567=GO_REF:0000041, GO:0001104=GO_REF:0000002, GO:0016592=PMID:14638676, GO:0005654=Reactome:REACT_12480} Q96G25 Mediator of RNA polymerase II transcription subunit 8 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0006367=TAS, GO:0016567=IEA, GO:0001104=IEA, GO:0016592=IDA, GO:0005654=TAS} gene expression, protein ubiquitination, transcription initiation from RNA polymerase II promoter mediator complex, nucleoplasm RNA polymerase II transcription cofactor activity, protein binding Human UniProtKB:Q15370 MED9 ENSEMBL UniProtKB {GO:0001104=GO_REF:0000002, GO:0016592=GO_REF:0000019} Q9NWA0 Mediator of RNA polymerase II transcription subunit 9 protein 20130413 {GO:0001104=IEA, GO:0016592=IEA} mediator complex RNA polymerase II transcription cofactor activity Human Ensembl:ENSMUSP00000080641 MEF2A GOC UniProtKB {GO:0005515=PMID:16043483, GO:0060045=GO_REF:0000019, GO:0003700=PMID:16043483, GO:0071300=GO_REF:0000019, GO:0003705=GO_REF:0000019, GO:0003139=GO_REF:0000019, GO:0035984=GO_REF:0000019, GO:0046332=PMID:11160896, GO:0003138=GO_REF:0000019, GO:0048703=GO_REF:0000019, GO:0051403=Reactome:REACT_21308, GO:0045652=GO_REF:0000019, GO:0007507=PMID:10458488, GO:0000165=PMID:9858528, GO:0014033=GO_REF:0000019, GO:0002062=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0033197=GO_REF:0000019, GO:0071864=GO_REF:0000019, GO:0002467=GO_REF:0000019, GO:0048311=GO_REF:0000024, GO:0035035=PMID:20590529, GO:0021542=GO_REF:0000019, GO:0001105=PMID:15466416, GO:0030501=GO_REF:0000019, GO:0072102=GO_REF:0000019, GO:0046982=PMID:9858528, GO:0007521=GO_REF:0000019, GO:0051149=Reactome:REACT_21402, GO:0007517=PMID:1516833, GO:0045087=Reactome:REACT_6802, GO:0010694=GO_REF:0000019, GO:0034166=Reactome:REACT_9027, GO:0060536=GO_REF:0000019, GO:0034162=Reactome:REACT_9047, GO:0051145=GO_REF:0000019, GO:0050853=GO_REF:0000019, GO:0001782=GO_REF:0000019, GO:0042826=PMID:10748098, GO:0030890=GO_REF:0000019, GO:0005634=PMID:16484498, GO:0042100=GO_REF:0000019, GO:0048666=GO_REF:0000019, GO:0006959=GO_REF:0000019, GO:0071277=PMID:16484498, GO:0030224=GO_REF:0000019, GO:0001046=GO_REF:0000019, GO:0030220=GO_REF:0000019, GO:2000987=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0001568=GO_REF:0000019, GO:0035690=GO_REF:0000019, GO:2000111=GO_REF:0000019, GO:0045669=GO_REF:0000019, GO:0001974=GO_REF:0000019, GO:0045666=GO_REF:0000019, GO:0000987=GO_REF:0000019, GO:0000790=GO_REF:0000024, GO:0006366=PMID:20590529, GO:0000981=PMID:10748098, GO:0050680=GO_REF:0000019, GO:0003185=GO_REF:0000019, GO:0042692=Reactome:REACT_21303, GO:0001947=GO_REF:0000019, GO:0002756=Reactome:REACT_6809, GO:0043524=GO_REF:0000019, GO:0002755=Reactome:REACT_27215, GO:0007611=GO_REF:0000019, GO:2001013=GO_REF:0000019, GO:0070375=PMID:15132737, GO:0055005=GO_REF:0000024, GO:0061337=GO_REF:0000024, GO:0038124=Reactome:REACT_8006, GO:0000977=PMID:20590529, GO:0038123=Reactome:REACT_8005, GO:0019901=GO_REF:0000019, GO:0034134=Reactome:REACT_7980, GO:0000122=PMID:16484498, GO:0002224=Reactome:REACT_9020, GO:0001649=GO_REF:0000019, GO:2000727=GO_REF:0000019, GO:0001958=GO_REF:0000019, GO:0071837=GO_REF:0000019, GO:0035666=Reactome:REACT_25281, GO:0005654=Reactome:REACT_21369, GO:0072160=GO_REF:0000019, GO:0034142=Reactome:REACT_6894, GO:0035914=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0045944=PMID:15466416, GO:0001085=PMID:15466416, GO:0014898=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:0033613=PMID:20590529, GO:0071333=GO_REF:0000019, GO:0034138=Reactome:REACT_6783, GO:0060025=GO_REF:0000019, GO:0002634=GO_REF:0000019, GO:0000002=GO_REF:0000024, GO:0006355=GO_REF:0000038, GO:0090073=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0030318=GO_REF:0000019, GO:0003677=GO_REF:0000038, GO:0006351=PMID:16043483, GO:0071498=GO_REF:0000019, GO:0003151=GO_REF:0000019, GO:0043565=PMID:10835359, GO:0048813=GO_REF:0000024, GO:0001077=GO_REF:0000019, GO:0071222=GO_REF:0000019, GO:0003211=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0010629=GO_REF:0000019, GO:0060297=GO_REF:0000019, GO:0034146=Reactome:REACT_9061} Q02078 Myocyte-specific enhancer factor 2A protein 20130413 {GO:0005515=IPI, GO:0060045=IEA, GO:0003700=IDA, GO:0071300=IEA, GO:0003705=IEA, GO:0003139=IEA, GO:0035984=IEA, GO:0046332=IPI, GO:0003138=IEA, GO:0048703=IEA, GO:0051403=TAS, GO:0045652=IEA, GO:0007507=IEP, GO:0000165=IDA, GO:0014033=IEA, GO:0002062=IEA, GO:0046983=IEA, GO:0033197=IEA, GO:0071864=IEA, GO:0002467=IEA, GO:0048311=ISS, GO:0035035=IPI, GO:0021542=IEA, GO:0001105=IDA, GO:0030501=IEA, GO:0072102=IEA, GO:0046982=IPI, GO:0007521=IEA, GO:0051149=TAS, GO:0007517=NAS, GO:0045087=TAS, GO:0010694=IEA, GO:0034166=TAS, GO:0060536=IEA, GO:0034162=TAS, GO:0051145=IEA, GO:0050853=IEA, GO:0001782=IEA, GO:0042826=IPI, GO:0030890=IEA, GO:0005634=IDA, GO:0042100=IEA, GO:0048666=IEA, GO:0006959=IEA, GO:0071277=IDA, GO:0030224=IEA, GO:0001046=IEA, GO:0030220=IEA, GO:2000987=IEA, GO:0048011=TAS, GO:0001568=IEA, GO:0035690=IEA, GO:2000111=IEA, GO:0045669=IEA, GO:0001974=IEA, GO:0045666=IEA, GO:0000987=IEA, GO:0000790=ISS, GO:0006366=IDA, GO:0000981=IDA, GO:0050680=IEA, GO:0003185=IEA, GO:0042692=TAS, GO:0001947=IEA, GO:0002756=TAS, GO:0043524=IEA, GO:0002755=TAS, GO:0007611=IEA, GO:2001013=IEA, GO:0070375=IMP, GO:0055005=ISS, GO:0061337=ISS, GO:0038124=TAS, GO:0000977=IDA, GO:0038123=TAS, GO:0019901=IEA, GO:0034134=TAS, GO:0000122=IDA, GO:0002224=TAS, GO:0001649=IEA, GO:2000727=IEA, GO:0001958=IEA, GO:0071837=IEA, GO:0035666=TAS, GO:0005654=TAS, GO:0072160=IEA, GO:0034142=TAS, GO:0035914=IEA, GO:0005737=IEA, GO:0045944=IDA, GO:0001085=IPI, GO:0014898=IEA, GO:0060021=IEA, GO:0033613=IPI, GO:0071333=IEA, GO:0034138=TAS, GO:0060025=IEA, GO:0002634=IEA, GO:0000002=ISS, GO:0006355=IEA, GO:0090073=IEA, GO:0006915=IEA, GO:0030318=IEA, GO:0003677=IEA, GO:0006351=IDA, GO:0071498=IEA, GO:0003151=IEA, GO:0043565=IDA, GO:0048813=ISS, GO:0001077=IEA, GO:0071222=IEA, GO:0003211=IEA, GO:0003682=IEA, GO:0010629=IEA, GO:0060297=IEA, GO:0034146=TAS} B cell homeostasis, B cell proliferation, B cell receptor signaling pathway, ERK5 cascade, MAPK cascade, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, apoptotic process, blood vessel development, blood vessel remodeling, cardiac conduction, cardiac muscle hypertrophy in response to stress, cardiac ventricle formation, cartilage morphogenesis, cellular response to calcium ion, cellular response to drug, cellular response to fluid shear stress, cellular response to glucose stimulus, cellular response to lipopolysaccharide, cellular response to retinoic acid, cellular response to trichostatin A, chondrocyte differentiation, dendrite morphogenesis, dentate gyrus development, embryonic viscerocranium morphogenesis, endochondral ossification, epithelial cell proliferation involved in renal tubule morphogenesis, germinal center formation, glomerulus morphogenesis, heart development, heart looping, humoral immune response, innate immune response, learning or memory, melanocyte differentiation, mitochondrial genome maintenance, mitochondrion distribution, monocyte differentiation, muscle cell differentiation, muscle cell fate determination, muscle organ development, negative regulation of epithelial cell proliferation, negative regulation of gene expression, negative regulation of neuron apoptotic process, negative regulation of transcription from RNA polymerase II promoter, nephron tubule epithelial cell differentiation, neural crest cell differentiation, neuron development, neurotrophin TRK receptor signaling pathway, osteoblast differentiation, outflow tract morphogenesis, palate development, platelet formation, positive regulation of B cell proliferation, positive regulation of alkaline phosphatase activity, positive regulation of behavioral fear response, positive regulation of bone mineralization, positive regulation of cardiac muscle cell differentiation, positive regulation of cardiac muscle cell proliferation, positive regulation of cell proliferation in bone marrow, positive regulation of macrophage apoptotic process, positive regulation of muscle cell differentiation, positive regulation of neuron differentiation, positive regulation of osteoblast differentiation, positive regulation of protein homodimerization activity, positive regulation of transcription from RNA polymerase II promoter, primary heart field specification, regulation of germinal center formation, regulation of megakaryocyte differentiation, regulation of sarcomere organization, regulation of synaptic activity, regulation of transcription, DNA-dependent, response to vitamin E, secondary heart field specification, sinoatrial valve morphogenesis, skeletal muscle cell differentiation, smooth muscle cell differentiation, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, transcription from RNA polymerase II promoter, transcription, DNA-dependent, ventricular cardiac myofibril development cytoplasm, nuclear chromatin, nucleoplasm, nucleus DNA binding, HMG box domain binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, RNA polymerase II regulatory region sequence-specific DNA binding, RNA polymerase II transcription coactivator activity, RNA polymerase II transcription factor binding, SMAD binding, activating transcription factor binding, chromatin binding, core promoter proximal region sequence-specific DNA binding, core promoter sequence-specific DNA binding, histone acetyltransferase binding, histone deacetylase binding, protein binding, protein dimerization activity, protein heterodimerization activity, protein kinase binding, sequence-specific DNA binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity Human MEF2B BHF-UCL UniProtKB {GO:0005667=PMID:15567413, GO:0006355=GO_REF:0000038, GO:0007517=PMID:1516833, GO:0003700=PMID:8575763, GO:0042826=PMID:15567413, GO:0046983=GO_REF:0000002, GO:0005634=PMID:1516833, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q02080 Myocyte-specific enhancer factor 2B protein 20090914 {GO:0005667=IDA, GO:0006355=IEA, GO:0007517=TAS, GO:0003700=NAS, GO:0042826=IPI, GO:0046983=IEA, GO:0005634=TAS, GO:0003677=IEA, GO:0006351=IEA} muscle organ development, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus, transcription factor complex DNA binding, histone deacetylase binding, protein dimerization activity, sequence-specific DNA binding transcription factor activity Human MEF2C GOC UniProtKB {GO:0060045=GO_REF:0000024, GO:0005515=PMID:16043483, GO:0003700=PMID:16043483, GO:0044212=GO_REF:0000024, GO:0071300=GO_REF:0000019, GO:0003705=GO_REF:0000019, GO:0003139=GO_REF:0000024, GO:0035984=GO_REF:0000024, GO:0071560=PMID:9770491, GO:0003138=GO_REF:0000024, GO:0048703=GO_REF:0000019, GO:0051403=Reactome:REACT_21308, GO:0045652=GO_REF:0000024, GO:0007507=GO_REF:0000024, GO:0002062=GO_REF:0000024, GO:0014033=PMID:21610032, GO:0000165=PMID:9858528, GO:0046983=GO_REF:0000002, GO:0033197=GO_REF:0000019, GO:0071864=GO_REF:0000019, GO:0002467=GO_REF:0000024, GO:0048311=GO_REF:0000019, GO:0021542=GO_REF:0000019, GO:0014902=PMID:8455629, GO:0030501=GO_REF:0000024, GO:0072102=GO_REF:0000024, GO:0046982=PMID:9858528, GO:0007521=GO_REF:0000024, GO:0048643=PMID:9770491, GO:0051149=Reactome:REACT_21402, GO:0007517=PMID:8455629, GO:0007519=GO_REF:0000024, GO:0045087=Reactome:REACT_6802, GO:0010694=GO_REF:0000024, GO:0034166=Reactome:REACT_9027, GO:0060536=GO_REF:0000019, GO:0034162=Reactome:REACT_9047, GO:0051145=GO_REF:0000024, GO:0050853=GO_REF:0000024, GO:0001782=GO_REF:0000024, GO:0042826=GO_REF:0000019, GO:0030890=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0042100=GO_REF:0000024, GO:0048666=GO_REF:0000024, GO:0071374=PMID:17696759, GO:0006959=GO_REF:0000024, GO:0030182=PMID:8455629, GO:0071277=GO_REF:0000024, GO:0030224=GO_REF:0000019, GO:0001046=GO_REF:0000019, GO:0030220=GO_REF:0000024, GO:2000987=GO_REF:0000024, GO:0048011=Reactome:REACT_11061, GO:0001568=GO_REF:0000024, GO:0009615=PMID:21170291, GO:0035690=GO_REF:0000024, GO:2000111=GO_REF:0000024, GO:0007399=PMID:8455629, GO:0045669=GO_REF:0000024, GO:0035198=PMID:21170291, GO:0045666=GO_REF:0000024, GO:0001974=GO_REF:0000024, GO:0045663=PMID:9770491, GO:0000987=GO_REF:0000019, GO:0000790=GO_REF:0000019, GO:0006366=PMID:21610032, GO:0000983=PMID:8455629, GO:0000981=PMID:21610032, GO:0055012=GO_REF:0000024, GO:0050680=GO_REF:0000019, GO:0003185=GO_REF:0000024, GO:0043231=GO_REF:0000052, GO:0042692=Reactome:REACT_21303, GO:0061333=GO_REF:0000024, GO:0001947=GO_REF:0000024, GO:0002756=Reactome:REACT_6809, GO:0043524=GO_REF:0000024, GO:0002755=Reactome:REACT_27215, GO:0007611=GO_REF:0000024, GO:2001013=GO_REF:0000024, GO:0055005=GO_REF:0000019, GO:0061337=GO_REF:0000019, GO:2001016=PMID:21556048, GO:0038124=Reactome:REACT_8006, GO:0000977=PMID:8455629, GO:0038123=Reactome:REACT_8005, GO:0019901=GO_REF:0000019, GO:0034134=Reactome:REACT_7980, GO:0000122=PMID:18079734, GO:0002224=Reactome:REACT_9020, GO:0001649=GO_REF:0000024, GO:2000727=PMID:9857019, GO:0043234=PMID:15486975, GO:0001958=GO_REF:0000024, GO:0071837=GO_REF:0000019, GO:0035666=Reactome:REACT_25281, GO:0005654=Reactome:REACT_21369, GO:0045893=PMID:17696759, GO:0072160=GO_REF:0000024, GO:0034142=Reactome:REACT_6894, GO:0035914=GO_REF:0000019, GO:0005737=PMID:8455629, GO:0030279=PMID:17696759, GO:0045944=PMID:16043483, GO:0014898=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:0071333=GO_REF:0000019, GO:0033613=PMID:11160896, GO:0034138=Reactome:REACT_6783, GO:0060025=GO_REF:0000024, GO:0002634=GO_REF:0000024, GO:0000002=GO_REF:0000019, GO:0043066=PMID:18079734, GO:0006355=GO_REF:0000038, GO:0090073=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0030318=PMID:21610032, GO:0003677=GO_REF:0000038, GO:0071498=GO_REF:0000024, GO:0003151=GO_REF:0000024, GO:0006351=GO_REF:0000038, GO:0010628=PMID:9857019, GO:0001077=PMID:15486975, GO:0071222=GO_REF:0000024, GO:0016607=PMID:18079734, GO:0003680=PMID:15486975, GO:0003211=GO_REF:0000024, GO:0003682=GO_REF:0000019, GO:0010629=GO_REF:0000024, GO:0060297=GO_REF:0000019, GO:0034146=Reactome:REACT_9061} Q06413 Myocyte-specific enhancer factor 2C protein 20130413 {GO:0060045=ISS, GO:0005515=IPI, GO:0003700=IDA, GO:0044212=ISS, GO:0071300=IEA, GO:0003705=IEA, GO:0003139=ISS, GO:0035984=ISS, GO:0071560=IDA, GO:0003138=ISS, GO:0048703=IEA, GO:0051403=TAS, GO:0045652=ISS, GO:0007507=ISS, GO:0002062=ISS, GO:0014033=ISS, GO:0000165=IDA, GO:0046983=IEA, GO:0033197=IEA, GO:0071864=IEA, GO:0002467=ISS, GO:0048311=IEA, GO:0021542=IEA, GO:0014902=IEP, GO:0030501=ISS, GO:0072102=ISS, GO:0046982=IPI, GO:0007521=ISS, GO:0048643=IMP, GO:0051149=TAS, GO:0007517=TAS, GO:0007519=ISS, GO:0045087=TAS, GO:0010694=ISS, GO:0034166=TAS, GO:0060536=IEA, GO:0034162=TAS, GO:0051145=ISS, GO:0050853=ISS, GO:0001782=ISS, GO:0042826=IEA, GO:0030890=ISS, GO:0005634=IDA, GO:0042100=ISS, GO:0048666=ISS, GO:0071374=IDA, GO:0006959=ISS, GO:0030182=IEP, GO:0071277=ISS, GO:0030224=IEA, GO:0001046=IEA, GO:0030220=ISS, GO:2000987=ISS, GO:0048011=TAS, GO:0001568=ISS, GO:0009615=IEP, GO:0035690=ISS, GO:2000111=ISS, GO:0007399=TAS, GO:0045669=ISS, GO:0035198=IDA, GO:0045666=ISS, GO:0001974=ISS, GO:0045663=IMP, GO:0000987=IEA, GO:0000790=IEA, GO:0006366=ISS, GO:0000983=IDA, GO:0000981=ISS, GO:0055012=ISS, GO:0050680=IEA, GO:0003185=ISS, GO:0043231=IDA, GO:0042692=TAS, GO:0061333=ISS, GO:0001947=ISS, GO:0002756=TAS, GO:0043524=ISS, GO:0002755=TAS, GO:0007611=ISS, GO:2001013=ISS, GO:0055005=IEA, GO:0061337=IEA, GO:2001016=IDA, GO:0038124=TAS, GO:0000977=IDA, GO:0038123=TAS, GO:0019901=IEA, GO:0034134=TAS, GO:0000122=IMP, GO:0002224=TAS, GO:0001649=ISS, GO:2000727=IDA, GO:0043234=IDA, GO:0001958=ISS, GO:0071837=IEA, GO:0035666=TAS, GO:0005654=TAS, GO:0045893=IDA, GO:0072160=ISS, GO:0034142=TAS, GO:0035914=IEA, GO:0005737=IDA, GO:0030279=IDA, GO:0045944=IDA, GO:0014898=IEA, GO:0060021=IEA, GO:0071333=IEA, GO:0033613=IPI, GO:0034138=TAS, GO:0060025=ISS, GO:0002634=ISS, GO:0000002=IEA, GO:0043066=IMP, GO:0006355=IEA, GO:0090073=ISS, GO:0005730=IDA, GO:0006915=IEA, GO:0030318=ISS, GO:0003677=IEA, GO:0071498=ISS, GO:0003151=ISS, GO:0006351=IEA, GO:0010628=IDA, GO:0001077=IDA, GO:0071222=ISS, GO:0016607=IDA, GO:0003680=IDA, GO:0003211=ISS, GO:0003682=IEA, GO:0010629=ISS, GO:0060297=IEA, GO:0034146=TAS} B cell homeostasis, B cell proliferation, B cell receptor signaling pathway, MAPK cascade, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, apoptotic process, blood vessel development, blood vessel remodeling, cardiac conduction, cardiac muscle hypertrophy in response to stress, cardiac ventricle formation, cartilage morphogenesis, cellular response to calcium ion, cellular response to drug, cellular response to fluid shear stress, cellular response to glucose stimulus, cellular response to lipopolysaccharide, cellular response to parathyroid hormone stimulus, cellular response to retinoic acid, cellular response to transforming growth factor beta stimulus, cellular response to trichostatin A, chondrocyte differentiation, dentate gyrus development, embryonic viscerocranium morphogenesis, endochondral ossification, epithelial cell proliferation involved in renal tubule morphogenesis, germinal center formation, glomerulus morphogenesis, heart development, heart looping, humoral immune response, innate immune response, learning or memory, melanocyte differentiation, mitochondrial genome maintenance, mitochondrion distribution, monocyte differentiation, muscle cell differentiation, muscle cell fate determination, muscle organ development, myotube differentiation, negative regulation of apoptotic process, negative regulation of epithelial cell proliferation, negative regulation of gene expression, negative regulation of neuron apoptotic process, negative regulation of ossification, negative regulation of transcription from RNA polymerase II promoter, nephron tubule epithelial cell differentiation, nervous system development, neural crest cell differentiation, neuron development, neuron differentiation, neurotrophin TRK receptor signaling pathway, osteoblast differentiation, outflow tract morphogenesis, palate development, platelet formation, positive regulation of B cell proliferation, positive regulation of alkaline phosphatase activity, positive regulation of behavioral fear response, positive regulation of bone mineralization, positive regulation of cardiac muscle cell differentiation, positive regulation of cardiac muscle cell proliferation, positive regulation of cell proliferation in bone marrow, positive regulation of gene expression, positive regulation of macrophage apoptotic process, positive regulation of muscle cell differentiation, positive regulation of myoblast differentiation, positive regulation of neuron differentiation, positive regulation of osteoblast differentiation, positive regulation of protein homodimerization activity, positive regulation of skeletal muscle cell differentiation, positive regulation of skeletal muscle tissue development, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, primary heart field specification, regulation of germinal center formation, regulation of megakaryocyte differentiation, regulation of sarcomere organization, regulation of synaptic activity, regulation of transcription, DNA-dependent, renal tubule morphogenesis, response to virus, response to vitamin E, secondary heart field specification, sinoatrial valve morphogenesis, skeletal muscle cell differentiation, skeletal muscle tissue development, smooth muscle cell differentiation, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, transcription from RNA polymerase II promoter, transcription, DNA-dependent, ventricular cardiac muscle cell differentiation, ventricular cardiac myofibril development cytoplasm, intracellular membrane-bounded organelle, nuclear chromatin, nuclear speck, nucleolus, nucleoplasm, nucleus, protein complex AT DNA binding, DNA binding, HMG box domain binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, RNA polymerase II regulatory region sequence-specific DNA binding, activating transcription factor binding, chromatin binding, core promoter proximal region sequence-specific DNA binding, core promoter sequence-specific DNA binding, histone deacetylase binding, miRNA binding, protein binding, protein dimerization activity, protein heterodimerization activity, protein kinase binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding Human UniProtKB:Q8CFN5 MEF2D HPA UniProtKB {GO:0005515=PMID:16043483, GO:0003700=PMID:8575763, GO:0000977=PMID:20590529, GO:0006366=PMID:20590529, GO:0042826=PMID:20590529, GO:0000981=PMID:20590529, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000002, GO:0001649=GO_REF:0000019, GO:0007512=PMID:10458488, GO:0043231=GO_REF:0000052, GO:0007399=GO_REF:0000037, GO:0001958=GO_REF:0000019, GO:0007517=PMID:8269842, GO:0002062=GO_REF:0000019, GO:0045944=PMID:20590529, GO:0046983=GO_REF:0000002, GO:0033613=PMID:20590529} Q5T9U4 Myocyte-specific enhancer factor 2D protein 20101115 {GO:0005515=IPI, GO:0003700=NAS, GO:0000977=IDA, GO:0006366=IDA, GO:0042826=IPI, GO:0000981=IDA, GO:0005730=IDA, GO:0006915=IEA, GO:0005634=IDA, GO:0003677=IEA, GO:0001649=IEA, GO:0007512=IEP, GO:0043231=IDA, GO:0007399=IEA, GO:0001958=IEA, GO:0007517=TAS, GO:0002062=IEA, GO:0045944=IDA, GO:0046983=IEA, GO:0033613=IPI} adult heart development, apoptotic process, chondrocyte differentiation, endochondral ossification, muscle organ development, nervous system development, osteoblast differentiation, positive regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter intracellular membrane-bounded organelle, nucleolus, nucleus DNA binding, RNA polymerase II regulatory region sequence-specific DNA binding, activating transcription factor binding, histone deacetylase binding, protein binding, protein dimerization activity, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity Human MEFV BHF-UCL UniProtKB {GO:2001056=PMID:19158676, GO:0005875=PMID:11468188, GO:0032691=PMID:20041150, GO:0005874=GO_REF:0000037, GO:0071641=PMID:20041150, GO:0003779=PMID:11468188, GO:0005634=PMID:11115844, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_75934, GO:0004197=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0006954=PMID:11468188, GO:0032695=PMID:20041150, GO:0050728=PMID:16403826, GO:0045087=Reactome:REACT_6802, GO:0006508=GO_REF:0000002, GO:0008270=PMID:11115844} O15553 Pyrin protein 20120622 {GO:2001056=IDA, GO:0005875=IDA, GO:0032691=IMP, GO:0005874=IEA, GO:0071641=IMP, GO:0003779=IDA, GO:0005634=IDA, GO:0035872=TAS, GO:0005829=TAS, GO:0004197=IEA, GO:0005622=IEA, GO:0006954=IDA, GO:0032695=IMP, GO:0050728=IMP, GO:0045087=TAS, GO:0006508=IEA, GO:0008270=NAS} inflammatory response, innate immune response, negative regulation of inflammatory response, negative regulation of interleukin-1 beta production, negative regulation of interleukin-12 production, negative regulation of macrophage inflammatory protein 1 alpha production, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, positive regulation of cysteine-type endopeptidase activity, proteolysis cytosol, intracellular, microtubule, microtubule associated complex, nucleus actin binding, cysteine-type endopeptidase activity, zinc ion binding Human MEGF10 UniProtKB UniProtKB {GO:0016323=GO_REF:0000039, GO:0034109=PMID:22407321, GO:0014719=GO_REF:0000024, GO:0014841=GO_REF:0000024, GO:0001891=GO_REF:0000039, GO:0043654=GO_REF:0000019, GO:0055001=PMID:22101682, GO:0042995=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0051147=PMID:22101682, GO:0014816=PMID:22101682, GO:0048641=PMID:22101682} Q96KG7 Multiple epidermal growth factor-like domains protein 10 protein 20120403 {GO:0016323=IEA, GO:0034109=IDA, GO:0014719=ISS, GO:0014841=ISS, GO:0001891=IEA, GO:0043654=IEA, GO:0055001=IMP, GO:0042995=IEA, GO:0016021=IEA, GO:0051147=IMP, GO:0014816=IMP, GO:0048641=IMP} homotypic cell-cell adhesion, muscle cell development, recognition of apoptotic cell, regulation of muscle cell differentiation, regulation of skeletal muscle tissue development, satellite cell activation, satellite cell differentiation, satellite cell proliferation basolateral plasma membrane, cell projection, integral to membrane, phagocytic cup Human UniProtKB:Q6DIB5 MEGF11 UniProtKB UniProtKB {GO:0016323=GO_REF:0000039, GO:0034109=GO_REF:0000024, GO:0010842=GO_REF:0000024, GO:0016021=GO_REF:0000037} A6BM72 Multiple epidermal growth factor-like domains protein 11 protein 20120326 {GO:0016323=IEA, GO:0034109=ISS, GO:0010842=ISS, GO:0016021=IEA} homotypic cell-cell adhesion, retina layer formation basolateral plasma membrane, integral to membrane Human UniProtKB:Q80T91 MEGF6 IntAct UniProtKB {GO:0005515=PMID:21078624, GO:0008150=GO_REF:0000015, GO:0005509=GO_REF:0000029, GO:0005576=GO_REF:0000039, GO:0005575=GO_REF:0000015} O75095 Multiple epidermal growth factor-like domains protein 6 protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0005509=NAS, GO:0005576=IEA, GO:0005575=ND} biological_process cellular_component, extracellular region calcium ion binding, protein binding Human UniProtKB:O15265 MEGF8 IntAct UniProtKB {GO:0005515=PMID:21078624, GO:0008150=GO_REF:0000015, GO:0005198=GO_REF:0000029, GO:0005509=GO_REF:0000029, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} Q7Z7M0 Multiple epidermal growth factor-like domains protein 8 protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0005198=NAS, GO:0005509=NAS, GO:0005575=ND, GO:0016021=IEA} biological_process cellular_component, integral to membrane calcium ion binding, protein binding, structural molecule activity Human UniProtKB:O15265 MEI1 ENSEMBL UniProtKB {GO:0007286=GO_REF:0000019, GO:0007141=GO_REF:0000019} Q5TIA1 Meiosis inhibitor protein 1 protein 20130413 {GO:0007286=IEA, GO:0007141=IEA} male meiosis I, spermatid development Human Ensembl:ENSMUSP00000086582 MEIG1 ENSEMBL UniProtKB {GO:0005634=GO_REF:0000019, GO:0007283=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q5JSS6 Meiosis expressed gene 1 protein homolog protein 20130413 {GO:0005634=IEA, GO:0007283=IEA, GO:0030154=IEA} cell differentiation, spermatogenesis nucleus Human Ensembl:ENSMUSP00000070310 MEIS1 IntAct UniProtKB {GO:0005515=PMID:20541704, GO:0005667=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0046982=GO_REF:0000019, GO:0003705=GO_REF:0000019, GO:0060216=GO_REF:0000019, GO:0005634=GO_REF:0000040, GO:0001525=GO_REF:0000019, GO:0003677=GO_REF:0000038, GO:0043565=GO_REF:0000019, GO:0002089=GO_REF:0000019, GO:0045665=GO_REF:0000019, GO:0045638=GO_REF:0000024, GO:0003682=GO_REF:0000019} O00470 Homeobox protein Meis1 protein 20130415 {GO:0005515=IPI, GO:0005667=IEA, GO:0003700=IEA, GO:0046982=IEA, GO:0003705=IEA, GO:0060216=IEA, GO:0005634=IEA, GO:0001525=IEA, GO:0003677=IEA, GO:0043565=IEA, GO:0002089=IEA, GO:0045665=IEA, GO:0045638=ISS, GO:0003682=IEA} angiogenesis, definitive hemopoiesis, lens morphogenesis in camera-type eye, negative regulation of myeloid cell differentiation, negative regulation of neuron differentiation nucleus, transcription factor complex DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, chromatin binding, protein binding, protein heterodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:P16220 MEIS2 PINC UniProtKB {GO:0003712=GO_REF:0000024, GO:0043565=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0006366=PMID:10764806, GO:0045638=GO_REF:0000024, GO:0003714=PMID:10764806, GO:0045944=GO_REF:0000019, GO:0001654=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0000122=PMID:10764806, GO:0008134=GO_REF:0000024} O14770 Homeobox protein Meis2 protein 20030904 {GO:0003712=ISS, GO:0043565=IEA, GO:0003700=IEA, GO:0006366=TAS, GO:0045638=ISS, GO:0003714=TAS, GO:0045944=IEA, GO:0001654=IEA, GO:0005634=IEA, GO:0000122=TAS, GO:0008134=ISS} eye development, negative regulation of myeloid cell differentiation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription cofactor activity, transcription corepressor activity, transcription factor binding Human MEIS3 MGI UniProtKB {GO:0043565=PMID:17178831, GO:0051897=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0001077=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0003682=GO_REF:0000019, GO:0005634=GO_REF:0000039} Q99687 Homeobox protein Meis3 protein 20080309 {GO:0043565=IDA, GO:0051897=IEA, GO:0043066=IEA, GO:0001077=IEA, GO:0003700=IEA, GO:0003682=IEA, GO:0005634=IEA} negative regulation of apoptotic process, positive regulation of protein kinase B signaling cascade nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, chromatin binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human MELK IntAct UniProtKB {GO:0005515=PMID:17280616, GO:0030097=GO_REF:0000024, GO:0043065=GO_REF:0000024, GO:0005886=PMID:21145462, GO:0008283=PMID:17280616, GO:0005509=PMID:16216881, GO:0006915=PMID:17280616, GO:0005524=GO_REF:0000037, GO:0008289=GO_REF:0000037, GO:0061351=GO_REF:0000024, GO:0004672=GO_REF:0000002, GO:0046777=PMID:16216881, GO:0004674=PMID:12400006, GO:0000086=PMID:12400006, GO:0005938=PMID:16159311, GO:0004715=PMID:16216881} Q14680 Maternal embryonic leucine zipper kinase protein 20130415 {GO:0005515=IPI, GO:0030097=ISS, GO:0043065=ISS, GO:0005886=IDA, GO:0008283=IDA, GO:0005509=IDA, GO:0006915=IDA, GO:0005524=IEA, GO:0008289=IEA, GO:0061351=ISS, GO:0004672=IEA, GO:0046777=IDA, GO:0004674=IDA, GO:0000086=TAS, GO:0005938=IDA, GO:0004715=IDA} G2/M transition of mitotic cell cycle, apoptotic process, cell proliferation, hemopoiesis, neural precursor cell proliferation, positive regulation of apoptotic process, protein autophosphorylation cell cortex, plasma membrane ATP binding, calcium ion binding, lipid binding, non-membrane spanning protein tyrosine kinase activity, protein binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB:Q9BZR8 MEMO1 UniProtKB UniProtKB {GO:0032886=PMID:20937854, GO:0005634=PMID:16780588, GO:0005829=PMID:16780588} Q9Y316 Protein MEMO1 protein 20110501 {GO:0032886=IMP, GO:0005634=IDA, GO:0005829=IDA} regulation of microtubule-based process cytosol, nucleus Human MEN1 ENSEMBL UniProtKB {GO:0005515=PMID:12874027, GO:0051974=PMID:12837246, GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_12627, GO:0044212=PMID:20484083, GO:0048704=GO_REF:0000019, GO:0046329=PMID:12226747, GO:0003690=PMID:15331604, GO:0000165=PMID:12226747, GO:0007179=Reactome:REACT_6844, GO:0051781=GO_REF:0000019, GO:0030674=PMID:20484083, GO:0000785=PMID:12874027, GO:0009411=PMID:16690369, GO:0010332=PMID:12874027, GO:0000400=PMID:15331604, GO:0060135=GO_REF:0000019, GO:0000403=PMID:15331604, GO:0000122=GO_REF:0000019, GO:0045786=PMID:15331604, GO:0032925=GO_REF:0000019, GO:0018024=PMID:14992727, GO:0043280=GO_REF:0000019, GO:0043234=PMID:15199122, GO:0006281=PMID:12874027, GO:0002076=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0005654=Reactome:REACT_120994, GO:0045892=PMID:12226747, GO:0008285=GO_REF:0000019, GO:0045736=PMID:15640349, GO:0005634=GO_REF:0000019, GO:0032154=PMID:14508515, GO:0043433=PMID:11526476, GO:0016363=PMID:12874027, GO:0005829=PMID:14508515, GO:0032092=PMID:20484083, GO:0005737=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:0006338=GO_REF:0000019, GO:0007050=GO_REF:0000019, GO:0030511=PMID:11274402, GO:0001776=GO_REF:0000019, GO:0046621=GO_REF:0000019, GO:0030097=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0016571=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0002051=GO_REF:0000019, GO:0034968=PMID:14992727, GO:0070412=PMID:11274402, GO:0006351=Reactome:REACT_121061, GO:0006974=PMID:16690369, GO:0045669=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0035097=PMID:14992727, GO:0045668=GO_REF:0000019, GO:0047485=PMID:11526476, GO:0003682=GO_REF:0000019, GO:0031062=GO_REF:0000019, GO:0001933=PMID:12226747} Q9GZQ5 Menin protein 20130413 {GO:0005515=IPI, GO:0051974=IMP, GO:0010467=TAS, GO:0006367=TAS, GO:0044212=IDA, GO:0048704=IEA, GO:0046329=IDA, GO:0003690=IDA, GO:0000165=IDA, GO:0007179=TAS, GO:0051781=IEA, GO:0030674=IDA, GO:0000785=IDA, GO:0009411=IDA, GO:0010332=IDA, GO:0000400=IDA, GO:0060135=IEA, GO:0000403=IDA, GO:0000122=IEA, GO:0045786=IDA, GO:0032925=IEA, GO:0018024=IDA, GO:0043280=IEA, GO:0043234=IDA, GO:0006281=NAS, GO:0002076=IEA, GO:0007420=IEA, GO:0005654=TAS, GO:0045892=IDA, GO:0008285=IEA, GO:0045736=IMP, GO:0005634=IEA, GO:0032154=IDA, GO:0043433=IDA, GO:0016363=IDA, GO:0005829=IDA, GO:0032092=IDA, GO:0005737=IEA, GO:0045944=IEA, GO:0060021=IEA, GO:0006338=IEA, GO:0007050=IEA, GO:0030511=IMP, GO:0001776=IEA, GO:0046621=IEA, GO:0030097=IEA, GO:0043065=IEA, GO:0016571=IEA, GO:0005730=IDA, GO:0002051=IEA, GO:0034968=IDA, GO:0070412=IPI, GO:0006351=TAS, GO:0006974=IDA, GO:0045669=IEA, GO:0043565=IEA, GO:0035097=IPI, GO:0045668=IEA, GO:0047485=IPI, GO:0003682=IEA, GO:0031062=IEA, GO:0001933=IDA} DNA repair, MAPK cascade, brain development, cell cycle arrest, chromatin remodeling, embryonic skeletal system morphogenesis, gene expression, hemopoiesis, histone lysine methylation, histone methylation, leukocyte homeostasis, maternal process involved in female pregnancy, negative regulation of JNK cascade, negative regulation of cell cycle, negative regulation of cell proliferation, negative regulation of cyclin-dependent protein serine/threonine kinase activity, negative regulation of organ growth, negative regulation of osteoblast differentiation, negative regulation of protein phosphorylation, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of telomerase activity, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, osteoblast development, osteoblast fate commitment, palate development, positive regulation of apoptotic process, positive regulation of cell division, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of histone methylation, positive regulation of osteoblast differentiation, positive regulation of protein binding, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transforming growth factor beta receptor signaling pathway, regulation of activin receptor signaling pathway, response to DNA damage stimulus, response to UV, response to gamma radiation, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway chromatin, cleavage furrow, cytoplasm, cytosol, histone methyltransferase complex, nuclear matrix, nucleolus, nucleoplasm, nucleus, protein complex R-SMAD binding, Y-form DNA binding, chromatin binding, double-stranded DNA binding, four-way junction DNA binding, histone-lysine N-methyltransferase activity, protein N-terminus binding, protein binding, protein binding, bridging, sequence-specific DNA binding, transcription regulatory region DNA binding Human Ensembl:ENSMUSP00000109130 MEOX1 HPA UniProtKB {GO:0043565=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0003700=GO_REF:0000019, GO:0001757=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0071837=GO_REF:0000019, GO:0007275=PMID:7987315, GO:0005634=GO_REF:0000040} P50221 Homeobox protein MOX-1 protein 20111111 {GO:0043565=IEA, GO:0003674=ND, GO:0008150=ND, GO:0003700=IEA, GO:0001757=IEA, GO:0045944=IEA, GO:0003682=IEA, GO:0005730=IDA, GO:0071837=IEA, GO:0007275=TAS, GO:0005634=IEA} biological_process, multicellular organismal development, positive regulation of transcription from RNA polymerase II promoter, somite specification nucleolus, nucleus HMG box domain binding, chromatin binding, molecular_function, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human MEOX2 PINC UniProtKB {GO:0043565=PMID:9073066, GO:0005515=PMID:16335786, GO:0005737=PMID:16335786, GO:0003700=GO_REF:0000002, GO:0016607=GO_REF:0000039, GO:0007519=GO_REF:0000019, GO:0001757=GO_REF:0000019, GO:0008015=PMID:7713505, GO:0060021=GO_REF:0000019, GO:0007275=PMID:7713505, GO:0060173=GO_REF:0000019, GO:0001525=GO_REF:0000019} P50222 Homeobox protein MOX-2 protein 20030904 {GO:0043565=IDA, GO:0005515=IPI, GO:0005737=IDA, GO:0003700=IEA, GO:0016607=IEA, GO:0007519=IEA, GO:0001757=IEA, GO:0008015=TAS, GO:0060021=IEA, GO:0007275=TAS, GO:0060173=IEA, GO:0001525=IEA} angiogenesis, blood circulation, limb development, multicellular organismal development, palate development, skeletal muscle tissue development, somite specification cytoplasm, nuclear speck protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human MEP1A PINC UniProtKB {GO:0005887=PMID:8262185, GO:0007586=PMID:9288916, GO:0017090=GO_REF:0000019, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0004222=GO_REF:0000002, GO:0005615=PMID:8262185} Q16819 Meprin A subunit alpha protein 20030904 {GO:0005887=TAS, GO:0007586=TAS, GO:0017090=IEA, GO:0006508=IEA, GO:0008270=IEA, GO:0004222=IEA, GO:0005615=TAS} digestion, proteolysis extracellular space, integral to plasma membrane, meprin A complex metalloendopeptidase activity, zinc ion binding Human MEP1B PINC UniProtKB {GO:0006954=GO_REF:0000037, GO:0005886=PMID:9288916, GO:0016020=GO_REF:0000002, GO:0005887=PMID:9288916, GO:0007586=PMID:9288916, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0004222=GO_REF:0000019, GO:0005615=PMID:9288916} Q16820 Meprin A subunit beta protein 20030904 {GO:0006954=IEA, GO:0005886=TAS, GO:0016020=IEA, GO:0005887=TAS, GO:0007586=TAS, GO:0006508=IEA, GO:0008270=IEA, GO:0004222=IEA, GO:0005615=TAS} digestion, inflammatory response, proteolysis extracellular space, integral to plasma membrane, membrane, plasma membrane metalloendopeptidase activity, zinc ion binding Human MEPCE UniProtKB UniProtKB {GO:0040031=PMID:17643375, GO:0001510=PMID:17643375, GO:0016073=PMID:17643375, GO:0008757=PMID:17643375, GO:0008173=PMID:17643375} Q7L2J0 7SK snRNA methylphosphate capping enzyme protein 20121022 {GO:0040031=IDA, GO:0001510=IDA, GO:0016073=IDA, GO:0008757=IDA, GO:0008173=IDA} RNA methylation, snRNA metabolic process, snRNA modification RNA methyltransferase activity, S-adenosylmethionine-dependent methyltransferase activity Human MEPE IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0001501=PMID:10945470, GO:0005578=GO_REF:0000039, GO:0030502=GO_REF:0000019, GO:0031214=GO_REF:0000037, GO:0005201=PMID:10945470} Q9NQ76 Matrix extracellular phosphoglycoprotein protein 20130415 {GO:0005515=IPI, GO:0001501=TAS, GO:0005578=IEA, GO:0030502=IEA, GO:0031214=IEA, GO:0005201=TAS} biomineral tissue development, negative regulation of bone mineralization, skeletal system development proteinaceous extracellular matrix extracellular matrix structural constituent, protein binding Human UniProtKB:P16333 MERTK BHF-UCL UniProtKB {GO:0005515=PMID:20103767, GO:0006909=PMID:19204785, GO:0060041=GO_REF:0000019, GO:0005886=Reactome:REACT_12060, GO:0060068=GO_REF:0000019, GO:0007267=PMID:8086340, GO:0007283=GO_REF:0000019, GO:0050900=Reactome:REACT_12051, GO:0005737=PMID:19204785, GO:0034446=GO_REF:0000019, GO:0001779=GO_REF:0000019, GO:0043277=GO_REF:0000019, GO:0030168=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0004672=GO_REF:0000002, GO:0005887=PMID:8086340, GO:0007596=Reactome:REACT_604, GO:0043491=GO_REF:0000019, GO:0051250=GO_REF:0000019, GO:0006468=PMID:8086340, GO:0016021=GO_REF:0000038, GO:0004713=GO_REF:0000038, GO:0016028=PMID:19204785, GO:0004714=GO_REF:0000003, GO:0032940=GO_REF:0000019, GO:0007166=PMID:8086340, GO:0001750=GO_REF:0000019} Q12866 Tyrosine-protein kinase Mer protein 20111123 {GO:0005515=IPI, GO:0006909=IMP, GO:0060041=IEA, GO:0005886=TAS, GO:0060068=IEA, GO:0007267=TAS, GO:0007283=IEA, GO:0050900=TAS, GO:0005737=IDA, GO:0034446=IEA, GO:0001779=IEA, GO:0043277=IEA, GO:0030168=IEA, GO:0005524=IEA, GO:0004672=IEA, GO:0005887=TAS, GO:0007596=TAS, GO:0043491=IEA, GO:0051250=IEA, GO:0006468=TAS, GO:0016021=IEA, GO:0004713=IEA, GO:0016028=IDA, GO:0004714=IEA, GO:0032940=IEA, GO:0007166=TAS, GO:0001750=IEA} apoptotic cell clearance, blood coagulation, cell surface receptor signaling pathway, cell-cell signaling, leukocyte migration, natural killer cell differentiation, negative regulation of lymphocyte activation, phagocytosis, platelet activation, protein kinase B signaling cascade, protein phosphorylation, retina development in camera-type eye, secretion by cell, spermatogenesis, substrate adhesion-dependent cell spreading, vagina development cytoplasm, integral to membrane, integral to plasma membrane, photoreceptor outer segment, plasma membrane, rhabdomere ATP binding, protein binding, protein kinase activity, protein tyrosine kinase activity, transmembrane receptor protein tyrosine kinase activity Human MESDC1 null null {} null null null null {} null null null MESDC2 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0005886=GO_REF:0000019, GO:0006457=GO_REF:0000024, GO:0005783=GO_REF:0000039, GO:0034394=GO_REF:0000019, GO:0007498=PMID:11247670, GO:0005575=GO_REF:0000015, GO:0016055=GO_REF:0000037, GO:0050750=GO_REF:0000019} Q14696 LDLR chaperone MESD protein 20110622 {GO:0003674=ND, GO:0005886=IEA, GO:0006457=ISS, GO:0005783=IEA, GO:0034394=IEA, GO:0007498=NAS, GO:0005575=ND, GO:0016055=IEA, GO:0050750=IEA} Wnt receptor signaling pathway, mesoderm development, protein folding, protein localization to cell surface cellular_component, endoplasmic reticulum, plasma membrane low-density lipoprotein particle receptor binding, molecular_function Human UniProtKB:Q9ERE7 MEST PINC UniProtKB {GO:0016787=GO_REF:0000037, GO:0005783=GO_REF:0000024, GO:0005789=GO_REF:0000039, GO:0007498=PMID:9158153, GO:0016021=GO_REF:0000037, GO:0032526=GO_REF:0000019, GO:0010883=GO_REF:0000019, GO:0003824=GO_REF:0000002} Q5EB52 Mesoderm-specific transcript homolog protein protein 20070906 {GO:0016787=IEA, GO:0005783=ISS, GO:0005789=IEA, GO:0007498=TAS, GO:0016021=IEA, GO:0032526=IEA, GO:0010883=IEA, GO:0003824=IEA} mesoderm development, regulation of lipid storage, response to retinoic acid endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane catalytic activity, hydrolase activity Human MET BHF-UCL UniProtKB {GO:0005515=PMID:22897854, GO:0014812=GO_REF:0000019, GO:0005886=Reactome:REACT_19398, GO:0008283=PMID:10871856, GO:0000187=GO_REF:0000019, GO:0046777=GO_REF:0000019, GO:0009925=PMID:15314156, GO:0060665=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0045944=PMID:22521434, GO:0030534=GO_REF:0000019, GO:0005008=GO_REF:0000019, GO:0014902=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0042593=GO_REF:0000019, GO:0001890=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0010828=GO_REF:0000019, GO:0001889=GO_REF:0000019, GO:0007165=PMID:1846706, GO:0016020=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0005887=PMID:1846706, GO:1901299=PMID:20655899, GO:0004713=Reactome:REACT_19398, GO:0016021=PMID:2819873, GO:0051450=GO_REF:0000019, GO:0007166=PMID:2819873} P08581 Hepatocyte growth factor receptor protein 20120821 {GO:0005515=IPI, GO:0014812=IEA, GO:0005886=TAS, GO:0008283=TAS, GO:0000187=IEA, GO:0046777=IEA, GO:0009925=IDA, GO:0060665=IEA, GO:0007411=TAS, GO:0045944=IDA, GO:0030534=IEA, GO:0005008=IEA, GO:0014902=IEA, GO:0005576=IEA, GO:0042593=IEA, GO:0001890=IEA, GO:0005524=IEA, GO:0010828=IEA, GO:0001889=IEA, GO:0007165=TAS, GO:0016020=IEA, GO:0007420=IEA, GO:0005887=TAS, GO:1901299=IMP, GO:0004713=TAS, GO:0016021=NAS, GO:0051450=IEA, GO:0007166=NAS} activation of MAPK activity, adult behavior, axon guidance, brain development, cell proliferation, cell surface receptor signaling pathway, glucose homeostasis, liver development, muscle cell migration, myoblast proliferation, myotube differentiation, negative regulation of hydrogen peroxide-mediated programmed cell death, placenta development, positive regulation of glucose transport, positive regulation of transcription from RNA polymerase II promoter, protein autophosphorylation, regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling, signal transduction basal plasma membrane, extracellular region, integral to membrane, integral to plasma membrane, membrane, plasma membrane ATP binding, hepatocyte growth factor-activated receptor activity, protein binding, protein tyrosine kinase activity Human METAP1 HGNC UniProtKB {GO:0005737=PMID:14532271, GO:0009987=GO_REF:0000002, GO:0004177=PMID:16386852, GO:0006508=GO_REF:0000037, GO:0008235=PMID:16386852, GO:0018206=PMID:16386852, GO:0031365=PMID:16386852, GO:0006417=PMID:16386852, GO:0046872=GO_REF:0000037} P53582 Methionine aminopeptidase 1 protein 20060324 {GO:0005737=TAS, GO:0009987=IEA, GO:0004177=TAS, GO:0006508=IEA, GO:0008235=TAS, GO:0018206=TAS, GO:0031365=TAS, GO:0006417=TAS, GO:0046872=IEA} N-terminal protein amino acid modification, cellular process, peptidyl-methionine modification, proteolysis, regulation of translation cytoplasm aminopeptidase activity, metal ion binding, metalloexopeptidase activity Human METAP2 HGNC UniProtKB {GO:0005737=PMID:15102683, GO:0016485=PMID:8858118, GO:0009987=GO_REF:0000002, GO:0004177=PMID:8858118, GO:0006508=GO_REF:0000037, GO:0008235=PMID:8858118, GO:0018206=PMID:8858118, GO:0031365=PMID:8858118, GO:0046872=GO_REF:0000037} P50579 Methionine aminopeptidase 2 protein 20070327 {GO:0005737=IDA, GO:0016485=IDA, GO:0009987=IEA, GO:0004177=IDA, GO:0006508=IEA, GO:0008235=IDA, GO:0018206=IDA, GO:0031365=IDA, GO:0046872=IEA} N-terminal protein amino acid modification, cellular process, peptidyl-methionine modification, protein processing, proteolysis cytoplasm aminopeptidase activity, metal ion binding, metalloexopeptidase activity Human METTL1 GOC UniProtKB {GO:0005515=PMID:15861136, GO:0005737=GO_REF:0000052, GO:0000049=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008176=PMID:12403464, GO:0006400=PMID:12403464, GO:0036265=PMID:15861136, GO:0043231=GO_REF:0000052} Q9UBP6 tRNA (guanine-N(7)-)-methyltransferase protein 20130413 {GO:0005515=IPI, GO:0005737=IDA, GO:0000049=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008176=IDA, GO:0006400=IDA, GO:0036265=IDA, GO:0043231=IDA} RNA (guanine-N7)-methylation, tRNA modification cytoplasm, intracellular membrane-bounded organelle, nucleolus, nucleus protein binding, tRNA (guanine-N7-)-methyltransferase activity, tRNA binding Human METTL10 UniProtKB UniProtKB {GO:0008168=GO_REF:0000037} Q5JPI9 Methyltransferase-like protein 10 protein 20130413 {GO:0008168=IEA} methyltransferase activity Human UniProtKB-KW:KW-0489 METTL13 UniProtKB UniProtKB {GO:0008168=GO_REF:0000037} Q8N6R0 Methyltransferase-like protein 13 protein 20130413 {GO:0008168=IEA} methyltransferase activity Human UniProtKB-KW:KW-0489 METTL14 UniProtKB UniProtKB {GO:0001510=GO_REF:0000024, GO:0006139=GO_REF:0000002, GO:0008168=GO_REF:0000002, GO:0005634=GO_REF:0000024, GO:0016422=GO_REF:0000024} Q9HCE5 Methyltransferase-like protein 14 protein 20080314 {GO:0001510=ISS, GO:0006139=IEA, GO:0008168=IEA, GO:0005634=ISS, GO:0016422=ISS} RNA methylation, nucleobase-containing compound metabolic process nucleus mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity, methyltransferase activity Human UniProtKB:Q86U44 METTL15 InterPro UniProtKB {GO:0008168=GO_REF:0000002} F8WD83 Probable methyltransferase-like protein 15 protein 20130413 {GO:0008168=IEA} methyltransferase activity Human InterPro:IPR002903 METTL16 UniProtKB UniProtKB {GO:0008168=GO_REF:0000037} Q86W50 Methyltransferase-like protein 16 protein 20130413 {GO:0008168=IEA} methyltransferase activity Human UniProtKB-KW:KW-0489 METTL17 IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0005739=GO_REF:0000039, GO:0005507=GO_REF:0000002, GO:0008168=GO_REF:0000037, GO:0005840=GO_REF:0000037, GO:0006412=GO_REF:0000002} Q9H7H0 Methyltransferase-like protein 17, mitochondrial protein 20130415 {GO:0005515=IPI, GO:0005739=IEA, GO:0005507=IEA, GO:0008168=IEA, GO:0005840=IEA, GO:0006412=IEA} translation mitochondrion, ribosome copper ion binding, methyltransferase activity, protein binding Human UniProtKB:P54253 METTL18 InterPro UniProtKB {GO:0005737=GO_REF:0000002, GO:0008276=GO_REF:0000002} O95568 Histidine protein methyltransferase 1 homolog protein 20130413 {GO:0005737=IEA, GO:0008276=IEA} cytoplasm protein methyltransferase activity Human InterPro:IPR010456 METTL20 InterPro UniProtKB {GO:0005737=GO_REF:0000002, GO:0008276=GO_REF:0000002} Q8IXQ9 Methyltransferase-like protein 20 protein 20130413 {GO:0005737=IEA, GO:0008276=IEA} cytoplasm protein methyltransferase activity Human InterPro:IPR010456 METTL21A GOC UniProtKB {GO:0018022=PMID:22948820, GO:0006479=PMID:22948820, GO:0016021=GO_REF:0000037, GO:0016279=PMID:22948820} Q8WXB1 Protein-lysine methyltransferase METTL21A protein 20130413 {GO:0018022=IDA, GO:0006479=IDA, GO:0016021=IEA, GO:0016279=IDA} peptidyl-lysine methylation, protein methylation integral to membrane protein-lysine N-methyltransferase activity Human METTL21B LIFEdb UniProtKB {GO:0005622=GO_REF:0000054, GO:0008168=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q96AZ1 Protein-lysine methyltransferase METTL21B protein 20100607 {GO:0005622=IDA, GO:0008168=IEA, GO:0016021=IEA} integral to membrane, intracellular methyltransferase activity Human METTL21C GOC UniProtKB {GO:0018022=PMID:22948820, GO:0006479=PMID:22948820, GO:0016279=PMID:22948820} Q5VZV1 Protein-lysine methyltransferase METTL21C protein 20130413 {GO:0018022=IDA, GO:0006479=IDA, GO:0016279=IDA} peptidyl-lysine methylation, protein methylation protein-lysine N-methyltransferase activity Human METTL21D UniProtKB UniProtKB {GO:0005515=PMID:22948820, GO:0005575=GO_REF:0000015, GO:0016279=PMID:22948820, GO:0018023=PMID:22948820} Q9H867 Protein-lysine methyltransferase METTL21D protein 20121102 {GO:0005515=IPI, GO:0005575=ND, GO:0016279=IDA, GO:0018023=IDA} peptidyl-lysine trimethylation cellular_component protein binding, protein-lysine N-methyltransferase activity Human UniProtKB:Q3KRA9 METTL22 UniProtKB UniProtKB {GO:0008168=GO_REF:0000037} Q9BUU2 Methyltransferase-like protein 22 protein 20130413 {GO:0008168=IEA} methyltransferase activity Human UniProtKB-KW:KW-0489 METTL23 UniProtKB UniProtKB {GO:0008168=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q86XA0 Methyltransferase-like protein 23 protein 20130413 {GO:0008168=IEA, GO:0016021=IEA} integral to membrane methyltransferase activity Human UniProtKB-KW:KW-0812 METTL2A UniProtKB UniProtKB {GO:0008168=GO_REF:0000037} Q96IZ6 Methyltransferase-like protein 2A protein 20130413 {GO:0008168=IEA} methyltransferase activity Human UniProtKB-KW:KW-0489 METTL2B UniProtKB UniProtKB {GO:0008168=GO_REF:0000037} Q6P1Q9 Methyltransferase-like protein 2B protein 20130413 {GO:0008168=IEA} methyltransferase activity Human UniProtKB-KW:KW-0489 METTL3 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0001510=PMID:9409616, GO:0016607=GO_REF:0000039, GO:0003723=GO_REF:0000037, GO:0008168=GO_REF:0000038, GO:0005654=Reactome:REACT_1720, GO:0005634=PMID:9409616, GO:0016422=PMID:9409616} Q86U44 N6-adenosine-methyltransferase 70 kDa subunit protein 20130213 {GO:0010467=TAS, GO:0001510=IMP, GO:0016607=IEA, GO:0003723=IEA, GO:0008168=IEA, GO:0005654=TAS, GO:0005634=IDA, GO:0016422=IMP} RNA methylation, gene expression nuclear speck, nucleoplasm, nucleus RNA binding, mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity, methyltransferase activity Human METTL4 UniProtKB UniProtKB {GO:0006139=GO_REF:0000002, GO:0008168=GO_REF:0000037, GO:0003676=GO_REF:0000002} Q8N3J2 Methyltransferase-like protein 4 protein 20130413 {GO:0006139=IEA, GO:0008168=IEA, GO:0003676=IEA} nucleobase-containing compound metabolic process methyltransferase activity, nucleic acid binding Human UniProtKB-KW:KW-0489 METTL5 UniProtKB UniProtKB {GO:0005737=GO_REF:0000002, GO:0008168=GO_REF:0000037, GO:0008276=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q9NRN9 Methyltransferase-like protein 5 protein 20130413 {GO:0005737=IEA, GO:0008168=IEA, GO:0008276=IEA, GO:0003676=IEA} cytoplasm methyltransferase activity, nucleic acid binding, protein methyltransferase activity Human UniProtKB-KW:KW-0489 METTL6 UniProtKB UniProtKB {GO:0008168=GO_REF:0000037} Q8TCB7 Methyltransferase-like protein 6 protein 20130413 {GO:0008168=IEA} methyltransferase activity Human UniProtKB-KW:KW-0489 METTL7A UniProtKB UniProtKB {GO:0005811=GO_REF:0000039, GO:0016020=GO_REF:0000039, GO:0005783=GO_REF:0000039, GO:0008168=GO_REF:0000037} Q9H8H3 Methyltransferase-like protein 7A protein 20130413 {GO:0005811=IEA, GO:0016020=IEA, GO:0005783=IEA, GO:0008168=IEA} endoplasmic reticulum, lipid particle, membrane methyltransferase activity Human UniProtKB-SubCell:SL-0162 METTL7B UniProtKB UniProtKB {GO:0008168=GO_REF:0000037} Q6UX53 Methyltransferase-like protein 7B protein 20130413 {GO:0008168=IEA} methyltransferase activity Human UniProtKB-KW:KW-0489 METTL8 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0007519=GO_REF:0000019, GO:0008168=GO_REF:0000037, GO:0045444=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0004402=GO_REF:0000019} Q9H825 Methyltransferase-like protein 8 protein 20130413 {GO:0005737=IEA, GO:0007519=IEA, GO:0008168=IEA, GO:0045444=IEA, GO:0005634=IEA, GO:0004402=IEA} fat cell differentiation, skeletal muscle tissue development cytoplasm, nucleus histone acetyltransferase activity, methyltransferase activity Human UniProtKB-SubCell:SL-0086 METTL9 UniProtKB UniProtKB {GO:0005515=PMID:21784977} Q9H1A3 Methyltransferase-like protein 9 protein 20111209 {GO:0005515=IPI} protein binding Human UniProtKB:P26651 MEX3A UniProtKB UniProtKB {GO:0000932=GO_REF:0000039, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002} A1L020 RNA-binding protein MEX3A protein 20130413 {GO:0000932=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0008270=IEA} cytoplasmic mRNA processing body, nucleus RNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 MEX3B HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0046777=GO_REF:0000024, GO:0000932=GO_REF:0000039, GO:0003723=GO_REF:0000037, GO:0005509=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006468=GO_REF:0000024, GO:0008270=GO_REF:0000002} Q6ZN04 RNA-binding protein MEX3B protein 20110516 {GO:0005737=IDA, GO:0046777=ISS, GO:0000932=IEA, GO:0003723=IEA, GO:0005509=ISS, GO:0005730=IDA, GO:0005634=IDA, GO:0006468=ISS, GO:0008270=IEA} protein autophosphorylation, protein phosphorylation cytoplasm, cytoplasmic mRNA processing body, nucleolus, nucleus RNA binding, calcium ion binding, zinc ion binding Human MEX3C HPA UniProtKB {GO:0005737=GO_REF:0000039, GO:0016874=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0043231=GO_REF:0000052} Q5U5Q3 RNA-binding E3 ubiquitin-protein ligase MEX3C protein 20111111 {GO:0005737=IEA, GO:0016874=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0043231=IDA} cytoplasm, intracellular membrane-bounded organelle, nucleus RNA binding, ligase activity, zinc ion binding Human MEX3D BHF-UCL UniProtKB {GO:0061157=PMID:14769789, GO:0010609=PMID:14769789, GO:0048471=PMID:14769789, GO:0003723=GO_REF:0000002, GO:0017091=PMID:14769789, GO:0042981=PMID:14769789, GO:0005634=PMID:14769789, GO:0008270=GO_REF:0000002} Q86XN8 RNA-binding protein MEX3D protein 20121029 {GO:0061157=NAS, GO:0010609=NAS, GO:0048471=IDA, GO:0003723=IEA, GO:0017091=IDA, GO:0042981=NAS, GO:0005634=IDA, GO:0008270=IEA} mRNA destabilization, mRNA localization resulting in posttranscriptional regulation of gene expression, regulation of apoptotic process nucleus, perinuclear region of cytoplasm AU-rich element binding, RNA binding, zinc ion binding Human MFAP1 Reactome UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0030198=Reactome:REACT_118779, GO:0001527=PMID:1374398, GO:0005576=Reactome:REACT_150335} P55081 Microfibrillar-associated protein 1 protein 20130301 {GO:0008150=ND, GO:0003674=ND, GO:0030198=TAS, GO:0001527=IDA, GO:0005576=TAS} biological_process, extracellular matrix organization extracellular region, microfibril molecular_function Human MFAP2 Reactome UniProtKB {GO:0030198=Reactome:REACT_118779, GO:0001527=GO_REF:0000002, GO:0005576=Reactome:REACT_150459, GO:0001968=GO_REF:0000019, GO:0070051=GO_REF:0000019, GO:0030220=GO_REF:0000019} P55001 Microfibrillar-associated protein 2 protein 20130301 {GO:0030198=TAS, GO:0001527=IEA, GO:0005576=TAS, GO:0001968=IEA, GO:0070051=IEA, GO:0030220=IEA} extracellular matrix organization, platelet formation extracellular region, microfibril fibrinogen binding, fibronectin binding Human MFAP3 Reactome UniProtKB {GO:0005886=GO_REF:0000039, GO:0030198=Reactome:REACT_118779, GO:0005576=Reactome:REACT_150335, GO:0016021=GO_REF:0000037} P55082 Microfibril-associated glycoprotein 3 protein 20130301 {GO:0005886=IEA, GO:0030198=TAS, GO:0005576=TAS, GO:0016021=IEA} extracellular matrix organization extracellular region, integral to membrane, plasma membrane Human MFAP3L UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037} O75121 Microfibrillar-associated protein 3-like protein 20130413 {GO:0005886=IEA, GO:0016021=IEA} integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 MFAP4 Reactome UniProtKB {GO:0003674=GO_REF:0000015, GO:0030198=Reactome:REACT_118779, GO:0001527=PMID:7633408, GO:0005576=Reactome:REACT_150335, GO:0007155=GO_REF:0000029} P55083 Microfibril-associated glycoprotein 4 protein 20130301 {GO:0003674=ND, GO:0030198=TAS, GO:0001527=NAS, GO:0005576=TAS, GO:0007155=NAS} cell adhesion, extracellular matrix organization extracellular region, microfibril molecular_function Human MFAP5 Reactome UniProtKB {GO:0030198=Reactome:REACT_118779, GO:0001527=GO_REF:0000002, GO:0005576=Reactome:REACT_150459, GO:0043206=GO_REF:0000019, GO:0005201=PMID:8557636} Q13361 Microfibrillar-associated protein 5 protein 20130301 {GO:0030198=TAS, GO:0001527=IEA, GO:0005576=TAS, GO:0043206=IEA, GO:0005201=TAS} extracellular fibril organization, extracellular matrix organization extracellular region, microfibril extracellular matrix structural constituent Human MFF HPA UniProtKB {GO:0005515=PMID:21149567, GO:0010821=PMID:21149567, GO:1900063=PMID:18353969, GO:0005741=PMID:21149567, GO:0001836=PMID:18353969, GO:0043653=PMID:21149567, GO:0005737=GO_REF:0000052, GO:0070584=PMID:21149567, GO:0032592=PMID:18353969, GO:0090200=PMID:21149567, GO:0051260=PMID:18353969, GO:0005777=PMID:18353969, GO:0016559=PMID:21149567} Q9GZY8 Mitochondrial fission factor protein 20081203 {GO:0005515=IPI, GO:0010821=IMP, GO:1900063=IMP, GO:0005741=IDA, GO:0001836=IMP, GO:0043653=IMP, GO:0005737=IDA, GO:0070584=IMP, GO:0032592=IDA, GO:0090200=IMP, GO:0051260=IDA, GO:0005777=IDA, GO:0016559=IMP} mitochondrial fragmentation involved in apoptotic process, mitochondrion morphogenesis, peroxisome fission, positive regulation of release of cytochrome c from mitochondria, protein homooligomerization, regulation of mitochondrion organization, regulation of peroxisome organization, release of cytochrome c from mitochondria cytoplasm, integral to mitochondrial membrane, mitochondrial outer membrane, peroxisome protein binding Human MFGE8 Reactome UniProtKB {GO:0008429=GO_REF:0000019, GO:2000427=GO_REF:0000019, GO:0005576=Reactome:REACT_75905, GO:0001525=GO_REF:0000037, GO:0006910=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0006911=GO_REF:0000019, GO:0007338=GO_REF:0000037, GO:0005178=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0001786=GO_REF:0000019, GO:0007155=GO_REF:0000037, GO:0009897=GO_REF:0000019, GO:0019897=GO_REF:0000019} Q08431 Lactadherin protein 20101014 {GO:0008429=IEA, GO:2000427=IEA, GO:0005576=TAS, GO:0001525=IEA, GO:0006910=IEA, GO:0005615=IEA, GO:0006911=IEA, GO:0007338=IEA, GO:0005178=IEA, GO:0019048=IEA, GO:0001786=IEA, GO:0007155=IEA, GO:0009897=IEA, GO:0019897=IEA} angiogenesis, cell adhesion, phagocytosis, engulfment, phagocytosis, recognition, positive regulation of apoptotic cell clearance, single fertilization, virus-host interaction external side of plasma membrane, extracellular region, extracellular space, extrinsic to plasma membrane integrin binding, phosphatidylethanolamine binding, phosphatidylserine binding Human MFI2 PINC UniProtKB {GO:0005515=PMID:19815549, GO:0006879=GO_REF:0000002, GO:0005506=PMID:2419904, GO:0005887=PMID:2419904, GO:0006826=GO_REF:0000002, GO:0005576=GO_REF:0000002, GO:0031225=GO_REF:0000037, GO:0008199=GO_REF:0000002} P08582 Melanotransferrin protein 20030904 {GO:0005515=IPI, GO:0006879=IEA, GO:0005506=TAS, GO:0005887=TAS, GO:0006826=IEA, GO:0005576=IEA, GO:0031225=IEA, GO:0008199=IEA} cellular iron ion homeostasis, iron ion transport anchored to membrane, extracellular region, integral to plasma membrane ferric iron binding, iron ion binding, protein binding Human MFN1 BHF-UCL UniProtKB {GO:0008053=PMID:20436456, GO:0003924=GO_REF:0000029, GO:0005741=GO_REF:0000039, GO:0016021=GO_REF:0000029, GO:0005525=GO_REF:0000037} Q8IWA4 Mitofusin-1 protein 20110404 {GO:0008053=IDA, GO:0003924=NAS, GO:0005741=IEA, GO:0016021=NAS, GO:0005525=IEA} mitochondrial fusion integral to membrane, mitochondrial outer membrane GTP binding, GTPase activity Human MFN2 ENSEMBL UniProtKB {GO:0005515=PMID:17121834, GO:0006626=PMID:11181170, GO:0003924=GO_REF:0000002, GO:0001825=GO_REF:0000019, GO:0005741=GO_REF:0000002, GO:0048662=GO_REF:0000002, GO:0048593=GO_REF:0000019, GO:0005525=GO_REF:0000037, GO:0005829=GO_REF:0000024, GO:0005739=PMID:11181170, GO:0046580=PMID:15322553, GO:0008053=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0015630=GO_REF:0000019, GO:0031306=GO_REF:0000024, GO:0007006=PMID:11181170, GO:0007050=GO_REF:0000024, GO:0016021=GO_REF:0000002, GO:0031625=PMID:16936636, GO:0051646=PMID:11181170} Q5JXC5 Mitofusin-2 protein 20130413 {GO:0005515=IPI, GO:0006626=IDA, GO:0003924=IEA, GO:0001825=IEA, GO:0005741=IEA, GO:0048662=IEA, GO:0048593=IEA, GO:0005525=IEA, GO:0005829=ISS, GO:0005739=IDA, GO:0046580=IDA, GO:0008053=IEA, GO:0007596=TAS, GO:0015630=IEA, GO:0031306=ISS, GO:0007006=IDA, GO:0007050=ISS, GO:0016021=IEA, GO:0031625=IPI, GO:0051646=IDA} blastocyst formation, blood coagulation, camera-type eye morphogenesis, cell cycle arrest, mitochondrial fusion, mitochondrial membrane organization, mitochondrion localization, negative regulation of Ras protein signal transduction, negative regulation of smooth muscle cell proliferation, protein targeting to mitochondrion cytosol, integral to membrane, intrinsic to mitochondrial outer membrane, microtubule cytoskeleton, mitochondrial outer membrane, mitochondrion GTP binding, GTPase activity, protein binding, ubiquitin protein ligase binding Human Ensembl:ENSMUSP00000030884 MFNG PINC UniProtKB {GO:0045747=GO_REF:0000019, GO:0033829=GO_REF:0000003, GO:0007389=GO_REF:0000002, GO:0030173=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0016757=GO_REF:0000002, GO:0005615=PMID:9187150, GO:0046872=GO_REF:0000037, GO:0032092=GO_REF:0000019} O00587 Beta-1,3-N-acetylglucosaminyltransferase manic fringe protein 20030904 {GO:0045747=IEA, GO:0033829=IEA, GO:0007389=IEA, GO:0030173=IEA, GO:0016020=IEA, GO:0016757=IEA, GO:0005615=TAS, GO:0046872=IEA, GO:0032092=IEA} pattern specification process, positive regulation of Notch signaling pathway, positive regulation of protein binding extracellular space, integral to Golgi membrane, membrane O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity, metal ion binding, transferase activity, transferring glycosyl groups Human MFRP UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0009790=PMID:11263980, GO:0016021=PMID:11263980} Q9BY79 Membrane frizzled-related protein protein 20020920 {GO:0003674=ND, GO:0009790=NAS, GO:0016021=TAS} embryo development integral to membrane molecular_function Human MFSD1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0055085=GO_REF:0000002} Q9H3U5 Major facilitator superfamily domain-containing protein 1 protein 20130413 {GO:0016021=IEA, GO:0055085=IEA} transmembrane transport integral to membrane Human UniProtKB-KW:KW-0812 MFSD10 GOC UniProtKB {GO:0015904=PMID:8353488, GO:0006810=PMID:8353488, GO:0006915=GO_REF:0000037, GO:0008493=PMID:8353488, GO:0016021=GO_REF:0000037, GO:0055085=GO_REF:0000002} Q14728 Major facilitator superfamily domain-containing protein 10 protein 20130413 {GO:0015904=TAS, GO:0006810=TAS, GO:0006915=IEA, GO:0008493=TAS, GO:0016021=IEA, GO:0055085=IEA} apoptotic process, tetracycline transport, transmembrane transport, transport integral to membrane tetracycline transporter activity Human MFSD3 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0055085=GO_REF:0000002} Q96ES6 Major facilitator superfamily domain-containing protein 3 protein 20130413 {GO:0016021=IEA, GO:0055085=IEA} transmembrane transport integral to membrane Human UniProtKB-KW:KW-0812 MFSD5 UniProtKB UniProtKB {GO:0006810=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q6N075 Major facilitator superfamily domain-containing protein 5 protein 20130413 {GO:0006810=IEA, GO:0016021=IEA} transport integral to membrane Human UniProtKB-KW:KW-0812 MGA UniProtKB UniProtKB {GO:0005667=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0071339=PMID:15960975, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8IWI9 MAX gene-associated protein protein 20091215 {GO:0005667=IEA, GO:0003700=IEA, GO:0071339=IDA, GO:0046983=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} transcription, DNA-dependent MLL1 complex, nucleus, transcription factor complex DNA binding, protein dimerization activity, sequence-specific DNA binding transcription factor activity Human MGAM Reactome UniProtKB {GO:0005886=Reactome:REACT_9506, GO:0005975=Reactome:REACT_474, GO:0004339=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0003824=PMID:9446624, GO:0004553=GO_REF:0000002, GO:0016324=GO_REF:0000039, GO:0032450=GO_REF:0000003, GO:0030246=GO_REF:0000002, GO:0005983=PMID:9446624, GO:0044245=Reactome:REACT_9472, GO:0016160=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0004558=Reactome:REACT_9506} O43451 Maltase-glucoamylase, intestinal protein 20061103 {GO:0005886=TAS, GO:0005975=TAS, GO:0004339=IEA, GO:0044281=TAS, GO:0003824=TAS, GO:0004553=IEA, GO:0016324=IEA, GO:0032450=IEA, GO:0030246=IEA, GO:0005983=TAS, GO:0044245=TAS, GO:0016160=IEA, GO:0016021=IEA, GO:0004558=TAS} carbohydrate metabolic process, polysaccharide digestion, small molecule metabolic process, starch catabolic process apical plasma membrane, integral to membrane, plasma membrane alpha-glucosidase activity, amylase activity, carbohydrate binding, catalytic activity, glucan 1,4-alpha-glucosidase activity, hydrolase activity, hydrolyzing O-glycosyl compounds, maltose alpha-glucosidase activity Human MGAT1 Reactome UniProtKB {GO:0008375=PMID:1702225, GO:0003827=GO_REF:0000003, GO:0000139=Reactome:REACT_25236, GO:0005975=PMID:1702225, GO:0006486=PMID:1702225, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006049=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} P26572 Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase protein 20130301 {GO:0008375=TAS, GO:0003827=IEA, GO:0000139=TAS, GO:0005975=TAS, GO:0006486=TAS, GO:0016021=IEA, GO:0044267=TAS, GO:0006049=IEA, GO:0001701=IEA, GO:0046872=IEA, GO:0043687=TAS, GO:0018279=TAS} UDP-N-acetylglucosamine catabolic process, carbohydrate metabolic process, cellular protein metabolic process, in utero embryonic development, post-translational protein modification, protein N-linked glycosylation via asparagine, protein glycosylation Golgi membrane, integral to membrane acetylglucosaminyltransferase activity, alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity, metal ion binding Human MGAT3 Reactome UniProtKB {GO:0000139=Reactome:REACT_25005, GO:0016020=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0006487=GO_REF:0000002, GO:0003830=GO_REF:0000003, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q09327 Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase protein 20130301 {GO:0000139=TAS, GO:0016020=IEA, GO:0016021=IEA, GO:0006487=IEA, GO:0003830=IEA, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS} cellular protein metabolic process, post-translational protein modification, protein N-linked glycosylation, protein N-linked glycosylation via asparagine Golgi membrane, integral to membrane, membrane beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity Human MGAT4B Reactome UniProtKB {GO:0000139=Reactome:REACT_25009, GO:0016758=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0005975=GO_REF:0000002, GO:0006491=PMID:10372966, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0046872=GO_REF:0000037, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426, GO:0008454=GO_REF:0000003} Q9UQ53 Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B protein 20130301 {GO:0000139=TAS, GO:0016758=IEA, GO:0016020=IEA, GO:0005975=IEA, GO:0006491=TAS, GO:0016021=IEA, GO:0044267=TAS, GO:0046872=IEA, GO:0043687=TAS, GO:0018279=TAS, GO:0008454=IEA} N-glycan processing, carbohydrate metabolic process, cellular protein metabolic process, post-translational protein modification, protein N-linked glycosylation via asparagine Golgi membrane, integral to membrane, membrane alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity, metal ion binding, transferase activity, transferring hexosyl groups Human MGAT5B UniProtKB UniProtKB {GO:0030144=GO_REF:0000003, GO:0000139=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0006487=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q3V5L5 Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B protein 20130413 {GO:0030144=IEA, GO:0000139=IEA, GO:0016021=IEA, GO:0006487=IEA, GO:0046872=IEA} protein N-linked glycosylation Golgi membrane, integral to membrane alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity, metal ion binding Human UniProtKB-SubCell:SL-0134 MGEA5 PINC UniProtKB {GO:0060124=GO_REF:0000019, GO:0070265=GO_REF:0000019, GO:0060051=GO_REF:0000019, GO:0051054=GO_REF:0000019, GO:0046060=GO_REF:0000019, GO:0010524=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0006044=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0048545=GO_REF:0000019, GO:0045862=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0010616=GO_REF:0000019, GO:0031343=GO_REF:0000019, GO:0051901=GO_REF:0000019, GO:0043243=GO_REF:0000019, GO:0006612=GO_REF:0000019, GO:0046326=GO_REF:0000019, GO:0006516=PMID:9811929, GO:0004415=PMID:9811929, GO:0032024=GO_REF:0000019, GO:0004402=GO_REF:0000003} O60502 Bifunctional protein NCOAT protein 20061106 {GO:0060124=IEA, GO:0070265=IEA, GO:0060051=IEA, GO:0051054=IEA, GO:0046060=IEA, GO:0010524=IEA, GO:0007568=IEA, GO:0006044=IEA, GO:0005634=IEA, GO:0048545=IEA, GO:0045862=IEA, GO:0005737=IEA, GO:0010616=IEA, GO:0031343=IEA, GO:0051901=IEA, GO:0043243=IEA, GO:0006612=IEA, GO:0046326=IEA, GO:0006516=TAS, GO:0004415=TAS, GO:0032024=IEA, GO:0004402=IEA} N-acetylglucosamine metabolic process, aging, dATP metabolic process, glycoprotein catabolic process, necrotic cell death, negative regulation of cardiac muscle adaptation, negative regulation of protein glycosylation, positive regulation of DNA metabolic process, positive regulation of calcium ion transport into cytosol, positive regulation of cell killing, positive regulation of glucose import, positive regulation of growth hormone secretion, positive regulation of insulin secretion, positive regulation of mitochondrial depolarization, positive regulation of protein complex disassembly, positive regulation of proteolysis, protein targeting to membrane, response to steroid hormone stimulus cytoplasm, nucleus histone acetyltransferase activity, hyalurononglucosaminidase activity Human MGLL Reactome UniProtKB {GO:0004091=GO_REF:0000037, GO:0019369=GO_REF:0000024, GO:0006629=Reactome:REACT_602, GO:0005886=Reactome:REACT_19155, GO:0045202=GO_REF:0000019, GO:0060292=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:2000124=GO_REF:0000024, GO:0042803=PMID:19957260, GO:0008289=GO_REF:0000019, GO:0006954=PMID:9495531, GO:0004622=PMID:9495531, GO:0047372=Reactome:REACT_120753, GO:0006633=GO_REF:0000037, GO:0019433=Reactome:REACT_494, GO:0046464=GO_REF:0000024, GO:0050727=GO_REF:0000024, GO:0030168=Reactome:REACT_798, GO:0009966=GO_REF:0000024, GO:0007596=Reactome:REACT_604, GO:0005789=Reactome:REACT_120753, GO:0036155=Reactome:REACT_121122, GO:0006644=Reactome:REACT_120870, GO:0051930=GO_REF:0000024, GO:0046474=Reactome:REACT_121401} Q99685 Monoglyceride lipase protein 20110819 {GO:0004091=IEA, GO:0019369=ISS, GO:0006629=TAS, GO:0005886=TAS, GO:0045202=IEA, GO:0060292=IEA, GO:0044281=TAS, GO:2000124=ISS, GO:0042803=IPI, GO:0008289=IEA, GO:0006954=TAS, GO:0004622=TAS, GO:0047372=TAS, GO:0006633=IEA, GO:0019433=TAS, GO:0046464=ISS, GO:0050727=ISS, GO:0030168=TAS, GO:0009966=ISS, GO:0007596=TAS, GO:0005789=TAS, GO:0036155=TAS, GO:0006644=TAS, GO:0051930=ISS, GO:0046474=TAS} acylglycerol acyl-chain remodeling, acylglycerol catabolic process, arachidonic acid metabolic process, blood coagulation, fatty acid biosynthetic process, glycerophospholipid biosynthetic process, inflammatory response, lipid metabolic process, long term synaptic depression, phospholipid metabolic process, platelet activation, regulation of endocannabinoid signaling pathway, regulation of inflammatory response, regulation of sensory perception of pain, regulation of signal transduction, small molecule metabolic process, triglyceride catabolic process endoplasmic reticulum membrane, plasma membrane, synapse acylglycerol lipase activity, carboxylesterase activity, lipid binding, lysophospholipase activity, protein homodimerization activity Human MGMT GOC UniProtKB {GO:0003908=GO_REF:0000003, GO:0042493=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0008168=PMID:2188979, GO:0005509=GO_REF:0000019, GO:0009636=GO_REF:0000019, GO:0005634=PMID:2188979, GO:0045739=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0071479=GO_REF:0000019, GO:0006306=PMID:2405387, GO:0051593=GO_REF:0000019, GO:0071407=GO_REF:0000019, GO:0006281=Reactome:REACT_216, GO:0060644=GO_REF:0000019, GO:0006307=GO_REF:0000019, GO:0043281=GO_REF:0000019, GO:0009008=PMID:2405387, GO:0060548=GO_REF:0000019, GO:0005654=Reactome:REACT_1876, GO:0034599=GO_REF:0000019, GO:0006266=PMID:2188979} P16455 Methylated-DNA--protein-cysteine methyltransferase protein 20130413 {GO:0003908=IEA, GO:0042493=IEA, GO:0045471=IEA, GO:0008168=TAS, GO:0005509=IEA, GO:0009636=IEA, GO:0005634=TAS, GO:0045739=IEA, GO:0003677=IEA, GO:0071479=IEA, GO:0006306=TAS, GO:0051593=IEA, GO:0071407=IEA, GO:0006281=TAS, GO:0060644=IEA, GO:0006307=IEA, GO:0043281=IEA, GO:0009008=TAS, GO:0060548=IEA, GO:0005654=TAS, GO:0034599=IEA, GO:0006266=TAS} DNA dealkylation involved in DNA repair, DNA ligation, DNA methylation, DNA repair, cellular response to ionizing radiation, cellular response to organic cyclic compound, cellular response to oxidative stress, mammary gland epithelial cell differentiation, negative regulation of cell death, positive regulation of DNA repair, regulation of cysteine-type endopeptidase activity involved in apoptotic process, response to drug, response to ethanol, response to folic acid, response to toxic substance nucleoplasm, nucleus "DNA binding, DNA-methyltransferase activity, calcium ion binding, methylated-DNA-protein""-cysteine S-methyltransferase activity, methyltransferase activity""" Human MGP PINC UniProtKB {GO:0031012=GO_REF:0000002, GO:0030500=GO_REF:0000002, GO:0001503=GO_REF:0000037, GO:0001502=PMID:9916809, GO:0005509=GO_REF:0000002, GO:0005578=PMID:9916809, GO:0005576=GO_REF:0000002, GO:0008147=PMID:9916809, GO:0030154=GO_REF:0000037, GO:0005201=PMID:9916809} P08493 Matrix Gla protein protein 20030904 {GO:0031012=IEA, GO:0030500=IEA, GO:0001503=IEA, GO:0001502=TAS, GO:0005509=IEA, GO:0005578=TAS, GO:0005576=IEA, GO:0008147=TAS, GO:0030154=IEA, GO:0005201=TAS} cartilage condensation, cell differentiation, ossification, regulation of bone mineralization extracellular matrix, extracellular region, proteinaceous extracellular matrix calcium ion binding, extracellular matrix structural constituent, structural constituent of bone Human MGRN1 UniProtKB UniProtKB {GO:0000209=GO_REF:0000019, GO:0005515=PMID:19737927, GO:0004842=PMID:17229889, GO:0045744=PMID:19737927, GO:0006513=PMID:17229889, GO:0005886=GO_REF:0000039, GO:0016874=GO_REF:0000038, GO:0008333=PMID:17229889, GO:0005634=PMID:17229889, GO:0005829=GO_REF:0000039, GO:0005737=PMID:19737927, GO:0008270=GO_REF:0000002, GO:0043951=PMID:19737927, GO:0005769=PMID:17229889} O60291 E3 ubiquitin-protein ligase MGRN1 protein 20120708 {GO:0000209=IEA, GO:0005515=IPI, GO:0004842=IDA, GO:0045744=IDA, GO:0006513=IMP, GO:0005886=IEA, GO:0016874=IEA, GO:0008333=IMP, GO:0005634=IDA, GO:0005829=IEA, GO:0005737=IDA, GO:0008270=IEA, GO:0043951=IDA, GO:0005769=IDA} endosome to lysosome transport, negative regulation of G-protein coupled receptor protein signaling pathway, negative regulation of cAMP-mediated signaling, protein monoubiquitination, protein polyubiquitination cytoplasm, cytosol, early endosome, nucleus, plasma membrane ligase activity, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q01726 MGST1 IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0006805=Reactome:REACT_13433, GO:0005783=GO_REF:0000024, GO:0042493=GO_REF:0000019, GO:0005743=GO_REF:0000019, GO:0045177=GO_REF:0000019, GO:0006749=GO_REF:0000019, GO:0010243=GO_REF:0000019, GO:0005741=GO_REF:0000039, GO:0005634=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0004364=PMID:20727966, GO:0042803=GO_REF:0000019, GO:0071449=PMID:20727966, GO:0005739=PMID:20727966, GO:0070207=GO_REF:0000024, GO:0043295=GO_REF:0000019, GO:0005789=Reactome:REACT_6947, GO:0032496=GO_REF:0000019, GO:0033327=GO_REF:0000019, GO:0016021=GO_REF:0000024, GO:0005778=GO_REF:0000024} P10620 Microsomal glutathione S-transferase 1 protein 20130415 {GO:0005515=IPI, GO:0006805=TAS, GO:0005783=ISS, GO:0042493=IEA, GO:0005743=IEA, GO:0045177=IEA, GO:0006749=IEA, GO:0010243=IEA, GO:0005741=IEA, GO:0005634=IEA, GO:0044281=TAS, GO:0004364=IDA, GO:0042803=IEA, GO:0071449=IDA, GO:0005739=IDA, GO:0070207=ISS, GO:0043295=IEA, GO:0005789=TAS, GO:0032496=IEA, GO:0033327=IEA, GO:0016021=ISS, GO:0005778=ISS} Leydig cell differentiation, cellular response to lipid hydroperoxide, glutathione metabolic process, protein homotrimerization, response to drug, response to lipopolysaccharide, response to organic nitrogen, small molecule metabolic process, xenobiotic metabolic process apical part of cell, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, mitochondrial inner membrane, mitochondrial outer membrane, mitochondrion, nucleus, peroxisomal membrane glutathione binding, glutathione transferase activity, protein binding, protein homodimerization activity Human UniProtKB:Q8WX92 MGST2 Reactome UniProtKB {GO:0019370=PMID:9092565, GO:0006805=Reactome:REACT_13433, GO:0005886=PMID:9092565, GO:0005783=GO_REF:0000033, GO:0044281=Reactome:REACT_111217, GO:0005635=GO_REF:0000033, GO:0004364=PMID:8703034, GO:0004464=PMID:9092565, GO:0043231=PMID:8703034, GO:0004602=GO_REF:0000033, GO:0006750=PMID:8703034, GO:0005789=Reactome:REACT_6947, GO:0016021=GO_REF:0000037, GO:0008047=GO_REF:0000002} Q99735 Microsomal glutathione S-transferase 2 protein 20130213 {GO:0019370=IDA, GO:0006805=TAS, GO:0005886=IDA, GO:0005783=IBA, GO:0044281=TAS, GO:0005635=IBA, GO:0004364=IDA, GO:0004464=IDA, GO:0043231=IDA, GO:0004602=IBA, GO:0006750=IDA, GO:0005789=TAS, GO:0016021=IEA, GO:0008047=IEA} glutathione biosynthetic process, leukotriene biosynthetic process, small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle, nuclear envelope, plasma membrane enzyme activator activity, glutathione peroxidase activity, glutathione transferase activity, leukotriene-C4 synthase activity Human MGST3 Reactome UniProtKB {GO:0006629=PMID:9278457, GO:0006805=Reactome:REACT_13433, GO:0005783=GO_REF:0000033, GO:0044281=Reactome:REACT_111217, GO:0005635=GO_REF:0000033, GO:0004364=GO_REF:0000033, GO:0043231=PMID:9278457, GO:0004602=GO_REF:0000033, GO:0007165=PMID:9278457, GO:0004601=PMID:9278457, GO:0016020=PMID:9278457, GO:0006750=GO_REF:0000033, GO:0005789=Reactome:REACT_6947, GO:0016021=GO_REF:0000037} O14880 Microsomal glutathione S-transferase 3 protein 20130213 {GO:0006629=TAS, GO:0006805=TAS, GO:0005783=IBA, GO:0044281=TAS, GO:0005635=IBA, GO:0004364=IBA, GO:0043231=TAS, GO:0004602=IBA, GO:0007165=TAS, GO:0004601=TAS, GO:0016020=TAS, GO:0006750=IBA, GO:0005789=TAS, GO:0016021=IEA} glutathione biosynthetic process, lipid metabolic process, signal transduction, small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle, membrane, nuclear envelope glutathione peroxidase activity, glutathione transferase activity, peroxidase activity Human MIA PINC UniProtKB {GO:0008283=PMID:7923218, GO:0005615=PMID:7923218, GO:0008083=GO_REF:0000037} Q16674 Melanoma-derived growth regulatory protein protein 20030904 {GO:0008283=TAS, GO:0005615=TAS, GO:0008083=IEA} cell proliferation extracellular space growth factor activity Human MIA2 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q96PC5 Melanoma inhibitory activity protein 2 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 MIA3 BHF-UCL UniProtKB {GO:0005515=PMID:17726152, GO:0030336=PMID:17044017, GO:0007162=PMID:17726152, GO:0042060=PMID:17044017, GO:0002687=PMID:17726152, GO:0005789=PMID:19269366, GO:0016021=PMID:19269366, GO:0015031=PMID:19269366, GO:0006887=PMID:19269366} Q5JRA6 Melanoma inhibitory activity protein 3 protein 20071123 {GO:0005515=IPI, GO:0030336=IDA, GO:0007162=IDA, GO:0042060=IDA, GO:0002687=IDA, GO:0005789=IDA, GO:0016021=IDA, GO:0015031=IMP, GO:0006887=IMP} exocytosis, negative regulation of cell adhesion, negative regulation of cell migration, positive regulation of leukocyte migration, protein transport, wound healing endoplasmic reticulum membrane, integral to membrane protein binding Human MIB1 HPA UniProtKB {GO:0005515=PMID:21903422, GO:0031965=GO_REF:0000052, GO:0004842=GO_REF:0000002, GO:0005813=PMID:21399614, GO:0001568=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0001756=GO_REF:0000019, GO:0031410=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0043231=GO_REF:0000052, GO:0001841=GO_REF:0000019, GO:0005829=Reactome:REACT_160213, GO:0001947=GO_REF:0000019, GO:0045807=GO_REF:0000019, GO:0045665=GO_REF:0000019, GO:0007219=Reactome:REACT_118859, GO:0008270=GO_REF:0000002} Q86YT6 E3 ubiquitin-protein ligase MIB1 protein 20101115 {GO:0005515=IPI, GO:0031965=IDA, GO:0004842=IEA, GO:0005813=IDA, GO:0001568=IEA, GO:0005886=IDA, GO:0001756=IEA, GO:0031410=IEA, GO:0001701=IEA, GO:0043231=IDA, GO:0001841=IEA, GO:0005829=TAS, GO:0001947=IEA, GO:0045807=IEA, GO:0045665=IEA, GO:0007219=TAS, GO:0008270=IEA} Notch signaling pathway, blood vessel development, heart looping, in utero embryonic development, negative regulation of neuron differentiation, neural tube formation, positive regulation of endocytosis, somitogenesis centrosome, cytoplasmic vesicle, cytosol, intracellular membrane-bounded organelle, nuclear membrane, plasma membrane protein binding, ubiquitin-protein ligase activity, zinc ion binding Human MIB2 IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0004842=GO_REF:0000002, GO:0007219=GO_REF:0000037, GO:0000151=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0004871=PMID:12761501, GO:0043123=PMID:12761501, GO:0005769=GO_REF:0000019, GO:0046872=GO_REF:0000002, GO:0005768=GO_REF:0000039} Q96AX9 E3 ubiquitin-protein ligase MIB2 protein 20130415 {GO:0005515=IPI, GO:0004842=IEA, GO:0007219=IEA, GO:0000151=IEA, GO:0003779=IEA, GO:0008270=IEA, GO:0004871=IMP, GO:0043123=IMP, GO:0005769=IEA, GO:0046872=IEA, GO:0005768=IEA} Notch signaling pathway, positive regulation of I-kappaB kinase/NF-kappaB cascade early endosome, endosome, ubiquitin ligase complex actin binding, metal ion binding, protein binding, signal transducer activity, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q9UHD2 MICA InterPro UniProtKB {GO:0030881=PMID:8901601, GO:0005886=Reactome:REACT_11178, GO:0009408=PMID:8901601, GO:0009986=PMID:18676862, GO:0042267=PMID:10426993, GO:0042612=GO_REF:0000002, GO:0046703=PMID:10426993, GO:0002418=PMID:10359807, GO:0046629=PMID:9497295, GO:0005615=PMID:18676862, GO:0006974=PMID:15995699, GO:0051607=PMID:16750166, GO:0006955=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0005887=PMID:18676862, GO:0001913=PMID:10426993, GO:0019882=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0050776=Reactome:REACT_11152, GO:0019835=GO_REF:0000037, GO:0042742=PMID:11830641} Q96QC4 MHC class I polypeptide-related sequence A protein 20130413 {GO:0030881=IDA, GO:0005886=TAS, GO:0009408=IDA, GO:0009986=IDA, GO:0042267=IDA, GO:0042612=IEA, GO:0046703=IPI, GO:0002418=IDA, GO:0046629=IDA, GO:0005615=IDA, GO:0006974=IDA, GO:0051607=IDA, GO:0006955=IEA, GO:0005737=IEA, GO:0005887=IDA, GO:0001913=IDA, GO:0019882=IEA, GO:0019048=IEA, GO:0050776=TAS, GO:0019835=IEA, GO:0042742=IDA} T cell mediated cytotoxicity, antigen processing and presentation, cytolysis, defense response to bacterium, defense response to virus, gamma-delta T cell activation, immune response, immune response to tumor cell, natural killer cell mediated cytotoxicity, regulation of immune response, response to DNA damage stimulus, response to heat, virus-host interaction MHC class I protein complex, cell surface, cytoplasm, extracellular space, integral to plasma membrane, plasma membrane beta-2-microglobulin binding, natural killer cell lectin-like receptor binding Human InterPro:IPR001039 MICAL1 UniProtKB UniProtKB {GO:0005882=PMID:11827972, GO:0005515=PMID:11827972, GO:0043066=GO_REF:0000019, GO:0017124=PMID:11827972, GO:0003779=PMID:21864500, GO:0004497=GO_REF:0000019, GO:0007165=PMID:11827972, GO:0071949=PMID:21864500, GO:0005737=PMID:11827972, GO:0016709=PMID:21864500, GO:0007010=PMID:11827972, GO:0001933=GO_REF:0000019, GO:0030042=PMID:21864500, GO:0008270=GO_REF:0000002, GO:0043154=GO_REF:0000019, GO:0055114=PMID:21864500} Q8TDZ2 Protein-methionine sulfoxide oxidase MICAL1 protein 20120228 {GO:0005882=NAS, GO:0005515=IPI, GO:0043066=IEA, GO:0017124=IPI, GO:0003779=IDA, GO:0004497=IEA, GO:0007165=NAS, GO:0071949=IDA, GO:0005737=IDA, GO:0016709=IDA, GO:0007010=NAS, GO:0001933=IEA, GO:0030042=IDA, GO:0008270=IEA, GO:0043154=IEA, GO:0055114=IDA} actin filament depolymerization, cytoskeleton organization, negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of protein phosphorylation, oxidation-reduction process, signal transduction cytoplasm, intermediate filament FAD binding, SH3 domain binding, actin binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen, protein binding, zinc ion binding Human MICAL2 UniProtKB UniProtKB {GO:0071949=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0016709=GO_REF:0000024, GO:0030042=GO_REF:0000024, GO:0003779=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0005856=GO_REF:0000039, GO:0055114=GO_REF:0000024} O94851 Protein-methionine sulfoxide oxidase MICAL2 protein 20120228 {GO:0071949=ISS, GO:0005737=IEA, GO:0016709=ISS, GO:0030042=ISS, GO:0003779=ISS, GO:0008270=IEA, GO:0005856=IEA, GO:0055114=ISS} actin filament depolymerization, oxidation-reduction process cytoplasm, cytoskeleton FAD binding, actin binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen, zinc ion binding Human UniProtKB:Q8TDZ2 MICAL3 UniProtKB UniProtKB {GO:0071949=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0016709=GO_REF:0000024, GO:0016491=GO_REF:0000002, GO:0030042=GO_REF:0000024, GO:0003779=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0005856=GO_REF:0000039, GO:0006887=GO_REF:0000037, GO:0055114=GO_REF:0000024} Q7RTP6 Protein-methionine sulfoxide oxidase MICAL3 protein 20120228 {GO:0071949=ISS, GO:0005737=IEA, GO:0016709=ISS, GO:0016491=IEA, GO:0030042=ISS, GO:0003779=ISS, GO:0008270=IEA, GO:0005856=IEA, GO:0006887=IEA, GO:0055114=ISS} actin filament depolymerization, exocytosis, oxidation-reduction process cytoplasm, cytoskeleton FAD binding, actin binding, oxidoreductase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen, zinc ion binding Human UniProtKB:Q8TDZ2 MICALCL UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000024, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0051019=GO_REF:0000024} Q6ZW33 MICAL C-terminal-like protein protein 20080725 {GO:0008150=ND, GO:0005737=ISS, GO:0007275=IEA, GO:0007283=IEA, GO:0030154=IEA, GO:0051019=ISS} biological_process, cell differentiation, multicellular organismal development, spermatogenesis cytoplasm mitogen-activated protein kinase binding Human MICALL1 UniProtKB UniProtKB {GO:0005515=PMID:19945174, GO:0005737=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0005856=GO_REF:0000039} Q8N3F8 MICAL-like protein 1 protein 20110208 {GO:0005515=IPI, GO:0005737=IEA, GO:0008270=IEA, GO:0005856=IEA} cytoplasm, cytoskeleton protein binding, zinc ion binding Human UniProtKB:P21754 MICALL2 ENSEMBL UniProtKB {GO:0005737=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0005923=GO_REF:0000019, GO:0032432=GO_REF:0000019, GO:0006897=GO_REF:0000019} Q8IY33 MICAL-like protein 2 protein 20130413 {GO:0005737=IEA, GO:0008270=IEA, GO:0005923=IEA, GO:0032432=IEA, GO:0006897=IEA} endocytosis actin filament bundle, cytoplasm, tight junction zinc ion binding Human Ensembl:ENSMUSP00000039707 MICB InterPro UniProtKB {GO:0050689=PMID:11239445, GO:0005886=Reactome:REACT_11178, GO:0009986=GO_REF:0000024, GO:0009408=PMID:9497295, GO:0002429=PMID:11491531, GO:0042612=GO_REF:0000002, GO:0046703=PMID:11491531, GO:0046629=PMID:9497295, GO:0006955=GO_REF:0000002, GO:0019882=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0050776=Reactome:REACT_11152, GO:0019835=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0032526=PMID:12569559, GO:0006979=PMID:11287116} Q5RIY5 MHC class I polypeptide-related sequence B protein 20130413 {GO:0050689=IDA, GO:0005886=TAS, GO:0009986=ISS, GO:0009408=IDA, GO:0002429=IDA, GO:0042612=IEA, GO:0046703=IDA, GO:0046629=IDA, GO:0006955=IEA, GO:0019882=IEA, GO:0019048=IEA, GO:0050776=TAS, GO:0019835=IEA, GO:0016021=IEA, GO:0032526=IDA, GO:0006979=IDA} antigen processing and presentation, cytolysis, gamma-delta T cell activation, immune response, immune response-activating cell surface receptor signaling pathway, negative regulation of defense response to virus by host, regulation of immune response, response to heat, response to oxidative stress, response to retinoic acid, virus-host interaction MHC class I protein complex, cell surface, integral to membrane, plasma membrane natural killer cell lectin-like receptor binding Human InterPro:IPR001039 MICU1 PINC UniProtKB {GO:0005622=PMID:9806765, GO:0005515=PMID:23178883, GO:0070509=PMID:20693986, GO:0006851=PMID:23101630, GO:0032592=PMID:23101630, GO:0051560=PMID:23101630, GO:0005509=PMID:23101630, GO:0005743=PMID:20693986, GO:0006952=PMID:9806765} Q9BPX6 Calcium uptake protein 1, mitochondrial protein 20030904 {GO:0005622=TAS, GO:0005515=IPI, GO:0070509=IDA, GO:0006851=IMP, GO:0032592=IDA, GO:0051560=IMP, GO:0005509=IDA, GO:0005743=IDA, GO:0006952=TAS} calcium ion import, defense response, mitochondrial calcium ion homeostasis, mitochondrial calcium ion transport integral to mitochondrial membrane, intracellular, mitochondrial inner membrane calcium ion binding, protein binding Human MID1 PINC UniProtKB {GO:0005622=GO_REF:0000002, GO:0007389=PMID:9354791, GO:0005881=PMID:18949047, GO:0005875=PMID:10077590, GO:0016874=GO_REF:0000037, GO:0005819=GO_REF:0000039, GO:0000226=PMID:10077590, GO:0032874=PMID:17438131, GO:0008270=GO_REF:0000002, GO:0031625=PMID:17438131} O15344 Midline-1 protein 20030904 {GO:0005622=IEA, GO:0007389=TAS, GO:0005881=IDA, GO:0005875=TAS, GO:0016874=IEA, GO:0005819=IEA, GO:0000226=TAS, GO:0032874=IMP, GO:0008270=IEA, GO:0031625=IPI} microtubule cytoskeleton organization, pattern specification process, positive regulation of stress-activated MAPK cascade cytoplasmic microtubule, intracellular, microtubule associated complex, spindle ligase activity, ubiquitin protein ligase binding, zinc ion binding Human MID1IP1 UniProtKB UniProtKB {GO:0006629=GO_REF:0000037, GO:0051351=GO_REF:0000024, GO:0051258=GO_REF:0000024, GO:0045723=GO_REF:0000024, GO:0015630=GO_REF:0000024, GO:0005874=GO_REF:0000037, GO:0007026=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0008022=GO_REF:0000019, GO:0046890=GO_REF:0000024, GO:0005829=GO_REF:0000024} Q9NPA3 Mid1-interacting protein 1 protein 20110121 {GO:0006629=IEA, GO:0051351=ISS, GO:0051258=ISS, GO:0045723=ISS, GO:0015630=ISS, GO:0005874=IEA, GO:0007026=ISS, GO:0005634=IEA, GO:0008022=IEA, GO:0046890=ISS, GO:0005829=ISS} lipid metabolic process, negative regulation of microtubule depolymerization, positive regulation of fatty acid biosynthetic process, positive regulation of ligase activity, protein polymerization, regulation of lipid biosynthetic process cytosol, microtubule, microtubule cytoskeleton, nucleus protein C-terminus binding Human UniProtKB:Q6P7D5 MID2 HPA UniProtKB {GO:0005622=GO_REF:0000002, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0016567=GO_REF:0000041, GO:0016874=GO_REF:0000037, GO:0005874=PMID:10400986, GO:0008270=GO_REF:0000002} Q9UJV3 Probable E3 ubiquitin-protein ligase MID2 protein 20101115 {GO:0005622=IEA, GO:0008150=ND, GO:0003674=ND, GO:0005813=IDA, GO:0005737=IDA, GO:0016567=IEA, GO:0016874=IEA, GO:0005874=IDA, GO:0008270=IEA} biological_process, protein ubiquitination centrosome, cytoplasm, intracellular, microtubule ligase activity, molecular_function, zinc ion binding Human MIDN UniProtKB UniProtKB {GO:0005730=GO_REF:0000039} Q504T8 Midnolin protein 20130413 {GO:0005730=IEA} nucleolus Human UniProtKB-SubCell:SL-0188 MIER1 HPA UniProtKB {GO:0005515=PMID:21258344, GO:0007165=PMID:12761501, GO:0005737=GO_REF:0000039, GO:0017053=PMID:12482978, GO:0003682=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0004871=PMID:12761501, GO:0043123=PMID:12761501, GO:0003677=GO_REF:0000002, GO:0031937=PMID:12482978, GO:0006351=GO_REF:0000037} Q8N108 Mesoderm induction early response protein 1 protein 20100326 {GO:0005515=IPI, GO:0007165=IMP, GO:0005737=IEA, GO:0017053=IDA, GO:0003682=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0004871=IMP, GO:0043123=IMP, GO:0003677=IEA, GO:0031937=IDA, GO:0006351=IEA} positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of chromatin silencing, signal transduction, transcription, DNA-dependent cytoplasm, nucleolus, nucleus, transcriptional repressor complex DNA binding, chromatin binding, protein binding, signal transducer activity NOT Human MIER2 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0003682=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q8N344 Mesoderm induction early response protein 2 protein 20130413 {GO:0006355=IEA, GO:0003682=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, chromatin binding Human UniProtKB-SubCell:SL-0191 MIER3 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0003682=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q7Z3K6 Mesoderm induction early response protein 3 protein 20130413 {GO:0006355=IEA, GO:0003682=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, chromatin binding Human UniProtKB-SubCell:SL-0191 MIF GOC UniProtKB {GO:0005515=PMID:17526494, GO:0071157=PMID:10562313, GO:0043498=PMID:12782713, GO:0030890=PMID:12782713, GO:0008283=PMID:12782713, GO:0043030=PMID:12782713, GO:0090344=PMID:10562313, GO:0050731=PMID:17045821, GO:0050715=PMID:19602265, GO:0048146=PMID:12782713, GO:0010739=PMID:17045821, GO:0005615=GO_REF:0000019, GO:0070207=PMID:17526494, GO:0033138=PMID:17045821, GO:0005737=GO_REF:0000039, GO:0006954=GO_REF:0000037, GO:0004167=PMID:17526494, GO:0001516=PMID:12782713, GO:0043406=GO_REF:0000019, GO:0002906=GO_REF:0000019, GO:0031666=GO_REF:0000019, GO:0070374=PMID:17045821, GO:0033033=GO_REF:0000019, GO:0043066=PMID:17045821, GO:0009986=PMID:12782713, GO:0030330=GO_REF:0000019, GO:0007569=GO_REF:0000019, GO:0005102=PMID:12782713, GO:0090238=GO_REF:0000019, GO:0061081=GO_REF:0000019, GO:0005576=PMID:12782713, GO:0050178=PMID:16285950, GO:0042056=PMID:19602265, GO:0005125=PMID:12782713, GO:0005126=PMID:17045821, GO:0032269=GO_REF:0000019, GO:0050918=PMID:19602265, GO:2000343=GO_REF:0000019, GO:0061078=GO_REF:0000019, GO:0045087=GO_REF:0000037, GO:0010629=PMID:10562313, GO:0043518=PMID:17045821, GO:0019752=PMID:12782713, GO:0007166=PMID:12782713, GO:0042327=PMID:12782713} P14174 Macrophage migration inhibitory factor protein 20130413 {GO:0005515=IPI, GO:0071157=IDA, GO:0043498=IDA, GO:0030890=IDA, GO:0008283=IDA, GO:0043030=NAS, GO:0090344=IDA, GO:0050731=IDA, GO:0050715=IDA, GO:0048146=IDA, GO:0010739=IDA, GO:0005615=IEA, GO:0070207=IPI, GO:0033138=IDA, GO:0005737=IEA, GO:0006954=IEA, GO:0004167=IDA, GO:0001516=IDA, GO:0043406=IEA, GO:0002906=IEA, GO:0031666=IEA, GO:0070374=IDA, GO:0033033=IEA, GO:0043066=IDA, GO:0009986=IDA, GO:0030330=IEA, GO:0007569=IEA, GO:0005102=IPI, GO:0090238=IEA, GO:0061081=IEA, GO:0005576=IDA, GO:0050178=IDA, GO:0042056=IDA, GO:0005125=IDA, GO:0005126=IPI, GO:0032269=IEA, GO:0050918=IDA, GO:2000343=IEA, GO:0061078=IEA, GO:0045087=IEA, GO:0010629=IDA, GO:0043518=IDA, GO:0019752=IDA, GO:0007166=IDA, GO:0042327=IDA} DNA damage response, signal transduction by p53 class mediator, carboxylic acid metabolic process, cell aging, cell proliferation, cell surface receptor signaling pathway, inflammatory response, innate immune response, negative regulation of DNA damage response, signal transduction by p53 class mediator, negative regulation of apoptotic process, negative regulation of cell aging, negative regulation of cell cycle arrest, negative regulation of cellular protein metabolic process, negative regulation of gene expression, negative regulation of mature B cell apoptotic process, negative regulation of myeloid cell apoptotic process, positive chemotaxis, positive regulation of B cell proliferation, positive regulation of ERK1 and ERK2 cascade, positive regulation of MAP kinase activity, positive regulation of arachidonic acid secretion, positive regulation of chemokine (C-X-C motif) ligand 2 production, positive regulation of cytokine secretion, positive regulation of fibroblast proliferation, positive regulation of lipopolysaccharide-mediated signaling pathway, positive regulation of myeloid leukocyte cytokine production involved in immune response, positive regulation of peptidyl-serine phosphorylation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of phosphorylation, positive regulation of prostaglandin secretion involved in immune response, positive regulation of protein kinase A signaling cascade, prostaglandin biosynthetic process, protein homotrimerization, regulation of macrophage activation cell surface, cytoplasm, extracellular region, extracellular space cell surface binding, chemoattractant activity, cytokine activity, cytokine receptor binding, dopachrome isomerase activity, phenylpyruvate tautomerase activity, protein binding, receptor binding Human MIF4GD InterPro UniProtKB {GO:0005515=PMID:21988832, GO:0005737=GO_REF:0000039, GO:0016070=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0008022=PMID:17577209, GO:0003677=GO_REF:0000002, GO:0006417=GO_REF:0000037} J3QRZ6 MIF4G domain-containing protein protein 20130413 {GO:0005515=IPI, GO:0005737=IEA, GO:0016070=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0008022=IPI, GO:0003677=IEA, GO:0006417=IEA} RNA metabolic process, regulation of translation cytoplasm, nucleus DNA binding, RNA binding, protein C-terminus binding, protein binding Human InterPro:IPR016021 MIIP null null {} null null null null {} null null null MINA HPA UniProtKB {GO:0001191=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0042254=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0016702=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0005829=GO_REF:0000019} Q8IUF8 Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA protein 20080818 {GO:0001191=IEA, GO:0005667=IEA, GO:0005737=IDA, GO:0042254=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0016702=IEA, GO:0046872=IEA, GO:0005829=IEA} ribosome biogenesis cytoplasm, cytosol, nucleolus, nucleus, transcription factor complex RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription, metal ion binding, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Human MINK1 PINC UniProtKB {GO:0005515=PMID:15469942, GO:0030424=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000037, GO:0046330=PMID:15469942, GO:2000311=GO_REF:0000024, GO:0007268=GO_REF:0000024, GO:0007243=GO_REF:0000024, GO:0005083=GO_REF:0000002, GO:0005737=PMID:18930710, GO:0046777=PMID:15469942, GO:0045211=GO_REF:0000037, GO:0030334=PMID:15469942, GO:0022407=PMID:15469942, GO:0005794=PMID:15469942, GO:0031532=PMID:15469942, GO:0007254=PMID:10708748, GO:0006950=GO_REF:0000024, GO:0014069=GO_REF:0000039, GO:0007275=GO_REF:0000024, GO:0005524=GO_REF:0000024, GO:0048813=GO_REF:0000024, GO:0004672=PMID:10708748, GO:0004674=PMID:18930710, GO:0001952=PMID:15469942, GO:0045060=GO_REF:0000019, GO:0006468=GO_REF:0000024} Q8N4C8 Misshapen-like kinase 1 protein 20050308 {GO:0005515=IPI, GO:0030424=IEA, GO:0030054=IEA, GO:0005886=IEA, GO:0046330=IMP, GO:2000311=ISS, GO:0007268=ISS, GO:0007243=ISS, GO:0005083=IEA, GO:0005737=IDA, GO:0046777=IDA, GO:0045211=IEA, GO:0030334=IMP, GO:0022407=IMP, GO:0005794=IDA, GO:0031532=IMP, GO:0007254=TAS, GO:0006950=ISS, GO:0014069=IEA, GO:0007275=ISS, GO:0005524=ISS, GO:0048813=ISS, GO:0004672=TAS, GO:0004674=IDA, GO:0001952=IMP, GO:0045060=IEA, GO:0006468=ISS} JNK cascade, actin cytoskeleton reorganization, dendrite morphogenesis, intracellular protein kinase cascade, multicellular organismal development, negative thymic T cell selection, positive regulation of JNK cascade, protein autophosphorylation, protein phosphorylation, regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity, regulation of cell migration, regulation of cell-cell adhesion, regulation of cell-matrix adhesion, response to stress, synaptic transmission Golgi apparatus, axon, cell junction, cytoplasm, plasma membrane, postsynaptic density, postsynaptic membrane ATP binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, small GTPase regulator activity Human MINOS1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000033, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005743=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q5TGZ0 Mitochondrial inner membrane organizing system protein 1 protein 20091130 {GO:0005739=IBA, GO:0003674=ND, GO:0008150=ND, GO:0005743=IEA, GO:0016021=IEA} biological_process integral to membrane, mitochondrial inner membrane, mitochondrion molecular_function Human MINPP1 BHF-UCL UniProtKB {GO:0034417=PMID:18413611, GO:0008969=PMID:10087200, GO:0052826=GO_REF:0000003, GO:0043647=Reactome:REACT_150253, GO:0001503=PMID:9923613, GO:0005783=PMID:10087200, GO:0003993=GO_REF:0000002, GO:0005788=Reactome:REACT_150382, GO:0006797=PMID:10087200, GO:0044281=Reactome:REACT_111217, GO:0030282=PMID:9923613} Q9UNW1 Multiple inositol polyphosphate phosphatase 1 protein 20080519 {GO:0034417=IDA, GO:0008969=TAS, GO:0052826=IEA, GO:0043647=TAS, GO:0001503=NAS, GO:0005783=TAS, GO:0003993=IEA, GO:0005788=TAS, GO:0006797=TAS, GO:0044281=TAS, GO:0030282=NAS} bone mineralization, inositol phosphate metabolic process, ossification, polyphosphate metabolic process, small molecule metabolic process endoplasmic reticulum, endoplasmic reticulum lumen acid phosphatase activity, bisphosphoglycerate 3-phosphatase activity, inositol hexakisphosphate 2-phosphatase activity, phosphohistidine phosphatase activity Human MIOS null null {} null null null null {} null null null MIOX UniProtKB UniProtKB {GO:0050661=GO_REF:0000019, GO:0019310=PMID:18364358, GO:0004033=GO_REF:0000024, GO:0050113=PMID:18364358, GO:0005737=GO_REF:0000024, GO:0005506=GO_REF:0000002, GO:0016234=GO_REF:0000024, GO:0016651=GO_REF:0000019, GO:0008199=PMID:18364358, GO:0016701=GO_REF:0000024} Q9UGB7 Inositol oxygenase protein 20110623 {GO:0050661=IEA, GO:0019310=IDA, GO:0004033=ISS, GO:0050113=IDA, GO:0005737=ISS, GO:0005506=IEA, GO:0016234=ISS, GO:0016651=IEA, GO:0008199=IDA, GO:0016701=ISS} inositol catabolic process cytoplasm, inclusion body NADP binding, aldo-keto reductase (NADP) activity, ferric iron binding, inositol oxygenase activity, iron ion binding, oxidoreductase activity, acting on NAD(P)H, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen Human MIP Reactome UniProtKB {GO:0005215=PMID:1840563, GO:0005212=GO_REF:0000019, GO:0005886=Reactome:REACT_23858, GO:0046691=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0043231=GO_REF:0000019, GO:0002088=GO_REF:0000019, GO:0005887=PMID:1840563, GO:0015250=GO_REF:0000019, GO:0015722=GO_REF:0000019, GO:0005921=GO_REF:0000039, GO:0006833=Reactome:REACT_23887, GO:0007601=GO_REF:0000019, GO:0050896=GO_REF:0000037} P30301 Lens fiber major intrinsic protein protein 20090808 {GO:0005215=TAS, GO:0005212=IEA, GO:0005886=TAS, GO:0046691=IEA, GO:0055085=TAS, GO:0043231=IEA, GO:0002088=IEA, GO:0005887=TAS, GO:0015250=IEA, GO:0015722=IEA, GO:0005921=IEA, GO:0006833=TAS, GO:0007601=IEA, GO:0050896=IEA} canalicular bile acid transport, lens development in camera-type eye, response to stimulus, transmembrane transport, visual perception, water transport gap junction, integral to plasma membrane, intracellular canaliculus, intracellular membrane-bounded organelle, plasma membrane structural constituent of eye lens, transporter activity, water channel activity Human MIPEP HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0006627=PMID:9073519, GO:0005759=GO_REF:0000039, GO:0006508=GO_REF:0000037, GO:0004222=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q99797 Mitochondrial intermediate peptidase protein 20111111 {GO:0005739=IDA, GO:0006627=TAS, GO:0005759=IEA, GO:0006508=IEA, GO:0004222=IEA, GO:0046872=IEA} protein processing involved in protein targeting to mitochondrion, proteolysis mitochondrial matrix, mitochondrion metal ion binding, metalloendopeptidase activity Human MIPOL1 MGI UniProtKB {GO:0005634=PMID:19667180} Q8TD10 Mirror-image polydactyly gene 1 protein protein 20120522 {GO:0005634=IDA} nucleus Human MIS12 LIFEdb UniProtKB {GO:0005515=PMID:15502821, GO:0000236=Reactome:REACT_682, GO:0005634=GO_REF:0000054, GO:0005829=Reactome:REACT_150414, GO:0007067=GO_REF:0000002, GO:0007059=PMID:16585270, GO:0051382=PMID:16585270, GO:0000087=Reactome:REACT_910, GO:0000444=PMID:16585270, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0000775=GO_REF:0000002, GO:0051301=GO_REF:0000037} Q9H081 Protein MIS12 homolog protein 20100607 {GO:0005515=IPI, GO:0000236=TAS, GO:0005634=IDA, GO:0005829=TAS, GO:0007067=IEA, GO:0007059=IMP, GO:0051382=IDA, GO:0000087=TAS, GO:0000444=IDA, GO:0000278=TAS, GO:0000090=TAS, GO:0000775=IEA, GO:0051301=IEA} M phase of mitotic cell cycle, cell division, chromosome segregation, kinetochore assembly, mitosis, mitotic anaphase, mitotic cell cycle, mitotic prometaphase MIS12/MIND type complex, chromosome, centromeric region, cytosol, nucleus protein binding Human MIS18A HPA UniProtKB {GO:0034080=Reactome:REACT_22186, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0007067=GO_REF:0000037, GO:0006334=Reactome:REACT_22344, GO:0005634=GO_REF:0000052, GO:0005654=Reactome:REACT_22185, GO:0005575=GO_REF:0000015, GO:0000775=GO_REF:0000039, GO:0051301=GO_REF:0000037} Q9NYP9 Protein Mis18-alpha protein 20110516 {GO:0034080=TAS, GO:0003674=ND, GO:0008150=ND, GO:0005737=IDA, GO:0007067=IEA, GO:0006334=TAS, GO:0005634=IDA, GO:0005654=TAS, GO:0005575=ND, GO:0000775=IEA, GO:0051301=IEA} CENP-A containing nucleosome assembly at centromere, biological_process, cell division, mitosis, nucleosome assembly cellular_component, chromosome, centromeric region, cytoplasm, nucleoplasm, nucleus molecular_function Human MIS18BP1 Reactome UniProtKB {GO:0034080=Reactome:REACT_22186, GO:0007067=GO_REF:0000037, GO:0003682=GO_REF:0000002, GO:0006334=Reactome:REACT_22344, GO:0005654=Reactome:REACT_22217, GO:0003677=GO_REF:0000037, GO:0000775=GO_REF:0000039, GO:0051301=GO_REF:0000037} Q6P0N0 Mis18-binding protein 1 protein 20100417 {GO:0034080=TAS, GO:0007067=IEA, GO:0003682=IEA, GO:0006334=TAS, GO:0005654=TAS, GO:0003677=IEA, GO:0000775=IEA, GO:0051301=IEA} CENP-A containing nucleosome assembly at centromere, cell division, mitosis, nucleosome assembly chromosome, centromeric region, nucleoplasm DNA binding, chromatin binding Human MITD1 HPA UniProtKB {GO:0005515=PMID:22190034, GO:0000281=PMID:23045692, GO:0031902=GO_REF:0000039, GO:0006810=GO_REF:0000037, GO:0030496=PMID:23045692, GO:0019898=PMID:23045692, GO:0043231=GO_REF:0000052} Q8WV92 MIT domain-containing protein 1 protein 20120912 {GO:0005515=IPI, GO:0000281=IMP, GO:0031902=IEA, GO:0006810=IEA, GO:0030496=IDA, GO:0019898=IDA, GO:0043231=IDA} cytokinesis after mitosis, transport extrinsic to membrane, intracellular membrane-bounded organelle, late endosome membrane, midbody protein binding Human MITF UniProtKB UniProtKB {GO:0005515=PMID:20530484, GO:0006355=PMID:9647758, GO:0043066=GO_REF:0000019, GO:0003705=GO_REF:0000019, GO:0030316=GO_REF:0000019, GO:0005634=PMID:9647758, GO:0030318=PMID:9647758, GO:0045670=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0043234=PMID:20530484, GO:0001077=PMID:20530484, GO:0006461=PMID:20530484, GO:0045165=GO_REF:0000019, GO:0046849=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0045944=PMID:20530484, GO:0003682=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0043010=GO_REF:0000019, GO:0045893=PMID:9647758, GO:0016055=GO_REF:0000019} O75030 Microphthalmia-associated transcription factor protein 20110627 {GO:0005515=IPI, GO:0006355=NAS, GO:0043066=IEA, GO:0003705=IEA, GO:0030316=IEA, GO:0005634=NAS, GO:0030318=NAS, GO:0045670=IEA, GO:0003677=IEA, GO:0043234=IDA, GO:0001077=IDA, GO:0006461=IDA, GO:0045165=IEA, GO:0046849=IEA, GO:0042127=IEA, GO:0045944=IDA, GO:0003682=IEA, GO:0046983=IEA, GO:0043010=IEA, GO:0045893=IDA, GO:0016055=IEA} Wnt receptor signaling pathway, bone remodeling, camera-type eye development, cell fate commitment, melanocyte differentiation, negative regulation of apoptotic process, osteoclast differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein complex assembly, regulation of cell proliferation, regulation of osteoclast differentiation, regulation of transcription, DNA-dependent nucleus, protein complex DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, chromatin binding, protein binding, protein dimerization activity Human UniProtKB:P48436 MKI67 HPA UniProtKB {GO:0005515=PMID:11342549, GO:0000793=GO_REF:0000019, GO:0008283=PMID:17577209, GO:0031100=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006259=GO_REF:0000019, GO:0008022=PMID:17577209, GO:0005524=GO_REF:0000037, GO:0034605=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0007126=GO_REF:0000019, GO:0000775=GO_REF:0000019} P46013 Antigen KI-67 protein 20101115 {GO:0005515=IPI, GO:0000793=IEA, GO:0008283=TAS, GO:0031100=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006259=IEA, GO:0008022=IPI, GO:0005524=IEA, GO:0034605=IEA, GO:0005737=IEA, GO:0007126=IEA, GO:0000775=IEA} DNA metabolic process, cell proliferation, cellular response to heat, meiosis, organ regeneration chromosome, centromeric region, condensed chromosome, cytoplasm, nucleolus, nucleus ATP binding, protein C-terminus binding, protein binding Human MKI67IP UniProtKB UniProtKB {GO:0005515=PMID:11342549, GO:0016072=PMID:11342549, GO:0000794=PMID:11342549, GO:0005737=PMID:11342549, GO:0006461=PMID:11342549, GO:0000166=GO_REF:0000002, GO:0010923=PMID:19389623, GO:0009303=PMID:11342549, GO:0003723=PMID:11342549, GO:0005730=PMID:11342549, GO:0005654=PMID:11342549, GO:0003676=GO_REF:0000002} Q9BYG3 MKI67 FHA domain-interacting nucleolar phosphoprotein protein 20111103 {GO:0005515=IPI, GO:0016072=NAS, GO:0000794=IDA, GO:0005737=IDA, GO:0006461=NAS, GO:0000166=IEA, GO:0010923=IDA, GO:0009303=NAS, GO:0003723=IDA, GO:0005730=IDA, GO:0005654=IDA, GO:0003676=IEA} negative regulation of phosphatase activity, protein complex assembly, rRNA metabolic process, rRNA transcription condensed nuclear chromosome, cytoplasm, nucleolus, nucleoplasm RNA binding, nucleic acid binding, nucleotide binding, protein binding Human MKKS HPA UniProtKB {GO:0008406=PMID:10802661, GO:0005515=PMID:22500027, GO:0038108=GO_REF:0000024, GO:0007608=GO_REF:0000024, GO:0007368=GO_REF:0000024, GO:0021987=GO_REF:0000024, GO:0007286=GO_REF:0000024, GO:0045776=GO_REF:0000019, GO:0045494=GO_REF:0000024, GO:0051877=GO_REF:0000024, GO:0032402=GO_REF:0000024, GO:0005829=GO_REF:0000039, GO:0001947=GO_REF:0000024, GO:0005622=GO_REF:0000054, GO:0007507=PMID:10802661, GO:0060027=GO_REF:0000024, GO:0006457=PMID:10802661, GO:0045444=GO_REF:0000024, GO:0040018=GO_REF:0000019, GO:0051131=GO_REF:0000019, GO:0005813=GO_REF:0000052, GO:0031514=GO_REF:0000024, GO:0046907=GO_REF:0000024, GO:0035058=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0048854=GO_REF:0000024, GO:0060296=GO_REF:0000024, GO:0021756=GO_REF:0000024, GO:0021766=GO_REF:0000024, GO:0042384=GO_REF:0000024, GO:0050910=GO_REF:0000024, GO:0060271=GO_REF:0000024, GO:0035176=GO_REF:0000024, GO:0010629=GO_REF:0000019, GO:0009296=GO_REF:0000024, GO:0051082=PMID:10802661} Q9NPJ1 McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin protein 20111111 {GO:0008406=TAS, GO:0005515=IPI, GO:0038108=ISS, GO:0007608=ISS, GO:0007368=ISS, GO:0021987=ISS, GO:0007286=ISS, GO:0045776=IEA, GO:0045494=ISS, GO:0051877=ISS, GO:0032402=ISS, GO:0005829=IEA, GO:0001947=ISS, GO:0005622=IDA, GO:0007507=TAS, GO:0060027=ISS, GO:0006457=TAS, GO:0045444=ISS, GO:0040018=IEA, GO:0051131=IEA, GO:0005813=IDA, GO:0031514=ISS, GO:0046907=ISS, GO:0035058=IEA, GO:0005524=IEA, GO:0048854=ISS, GO:0060296=ISS, GO:0021756=ISS, GO:0021766=ISS, GO:0042384=ISS, GO:0050910=ISS, GO:0060271=ISS, GO:0035176=ISS, GO:0010629=IEA, GO:0009296=ISS, GO:0051082=TAS} brain morphogenesis, cerebral cortex development, chaperone-mediated protein complex assembly, cilium assembly, cilium morphogenesis, convergent extension involved in gastrulation, detection of mechanical stimulus involved in sensory perception of sound, determination of left/right symmetry, fat cell differentiation, flagellum assembly, gonad development, heart development, heart looping, hippocampus development, intracellular transport, melanosome transport, negative regulation of appetite by leptin-mediated signaling pathway, negative regulation of blood pressure, negative regulation of gene expression, nonmotile primary cilium assembly, photoreceptor cell maintenance, pigment granule aggregation in cell center, positive regulation of multicellular organism growth, protein folding, regulation of cilium beat frequency involved in ciliary motility, sensory perception of smell, social behavior, spermatid development, striatum development centrosome, cytosol, intracellular, motile cilium ATP binding, protein binding, unfolded protein binding Human MKL1 HPA UniProtKB {GO:0005515=PMID:14565952, GO:0000976=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0003713=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0003785=GO_REF:0000024, GO:0043522=PMID:14970199, GO:0005737=GO_REF:0000052, GO:0045944=PMID:14970199, GO:0051145=PMID:14970199} Q969V6 MKL/myocardin-like protein 1 protein 20101115 {GO:0005515=IPI, GO:0000976=IEA, GO:0043066=IEA, GO:0003700=IEA, GO:0003713=ISS, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0006351=IEA, GO:0003785=ISS, GO:0043522=IPI, GO:0005737=IDA, GO:0045944=IDA, GO:0051145=IMP} negative regulation of apoptotic process, positive regulation of transcription from RNA polymerase II promoter, smooth muscle cell differentiation, transcription, DNA-dependent cytoplasm, nucleolus, nucleus actin monomer binding, leucine zipper domain binding, nucleic acid binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, transcription regulatory region sequence-specific DNA binding Human MKL2 IntAct UniProtKB {GO:0005515=PMID:14565952, GO:0010467=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0003713=PMID:14565952, GO:0048514=GO_REF:0000019, GO:0005634=PMID:14565952, GO:0003779=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0001701=GO_REF:0000019, GO:0045844=PMID:14565952, GO:0006351=GO_REF:0000037, GO:0001889=GO_REF:0000019, GO:0048738=GO_REF:0000019, GO:0003007=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0007517=GO_REF:0000037, GO:0045944=PMID:14565952, GO:0048568=GO_REF:0000019, GO:0051145=GO_REF:0000019} Q9ULH7 MKL/myocardin-like protein 2 protein 20130415 {GO:0005515=IPI, GO:0010467=IEA, GO:0003700=IEA, GO:0003713=IDA, GO:0048514=IEA, GO:0005634=IC, GO:0003779=IEA, GO:0003676=IEA, GO:0001701=IEA, GO:0045844=IDA, GO:0006351=IEA, GO:0001889=IEA, GO:0048738=IEA, GO:0003007=IEA, GO:0005737=IEA, GO:0007517=IEA, GO:0045944=IDA, GO:0048568=IEA, GO:0051145=IEA} blood vessel morphogenesis, cardiac muscle tissue development, embryonic organ development, gene expression, heart morphogenesis, in utero embryonic development, liver development, muscle organ development, positive regulation of striated muscle tissue development, positive regulation of transcription from RNA polymerase II promoter, smooth muscle cell differentiation, transcription, DNA-dependent cytoplasm, nucleus actin binding, nucleic acid binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity Human UniProtKB:P11831 MKLN1 PINC UniProtKB {GO:0007165=PMID:10640805, GO:0005737=GO_REF:0000039} Q9UL63 Muskelin protein 20050308 {GO:0007165=NAS, GO:0005737=IEA} signal transduction cytoplasm Human MKNK1 BHF-UCL UniProtKB {GO:0004672=GO_REF:0000002, GO:0018105=PMID:17130135, GO:0008543=Reactome:REACT_9470, GO:0004674=PMID:17130135, GO:0006468=PMID:9155018, GO:0005634=GO_REF:0000039, GO:0005524=PMID:9155018, GO:0007243=PMID:9155018, GO:0006417=GO_REF:0000037, GO:0005829=Reactome:REACT_111063} Q9BUB5 MAP kinase-interacting serine/threonine-protein kinase 1 protein 20110213 {GO:0004672=IEA, GO:0018105=IDA, GO:0008543=TAS, GO:0004674=IDA, GO:0006468=IDA, GO:0005634=IEA, GO:0005524=IDA, GO:0007243=IDA, GO:0006417=IEA, GO:0005829=TAS} fibroblast growth factor receptor signaling pathway, intracellular protein kinase cascade, peptidyl-serine phosphorylation, protein phosphorylation, regulation of translation cytosol, nucleus ATP binding, protein kinase activity, protein serine/threonine kinase activity Human MKNK2 InterPro UniProtKB {GO:0030097=PMID:21149447, GO:0006915=GO_REF:0000019, GO:0005524=GO_REF:0000002, GO:0007243=PMID:11463832, GO:0006417=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0004672=GO_REF:0000002, GO:0004674=PMID:11463832, GO:0016605=GO_REF:0000039, GO:0006468=PMID:11463832, GO:0071243=PMID:18299328, GO:0007166=PMID:8415712} Q9NV89 cDNA FLJ10868 fis, clone NT2RP4001644, weakly similar to MYOSIN LIGHT CHAIN KINASE (EC 2.7.1.117) protein 20130413 {GO:0030097=IDA, GO:0006915=IEA, GO:0005524=IEA, GO:0007243=IDA, GO:0006417=IEA, GO:0046872=IEA, GO:0005737=IEA, GO:0004672=IEA, GO:0004674=IDA, GO:0016605=IEA, GO:0006468=IDA, GO:0071243=IDA, GO:0007166=TAS} apoptotic process, cell surface receptor signaling pathway, cellular response to arsenic-containing substance, hemopoiesis, intracellular protein kinase cascade, protein phosphorylation, regulation of translation PML body, cytoplasm ATP binding, metal ion binding, protein kinase activity, protein serine/threonine kinase activity Human InterPro:IPR000719 MKRN1 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0016567=GO_REF:0000041, GO:0016874=GO_REF:0000037, GO:0003682=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0003676=GO_REF:0000002} Q9UHC7 E3 ubiquitin-protein ligase makorin-1 protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0016567=IEA, GO:0016874=IEA, GO:0003682=IEA, GO:0008270=IEA, GO:0005575=ND, GO:0003676=IEA} biological_process, protein ubiquitination cellular_component chromatin binding, ligase activity, molecular_function, nucleic acid binding, zinc ion binding Human MKRN2 UniProtKB UniProtKB {GO:0005622=PMID:11597136, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0016567=GO_REF:0000041, GO:0016874=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q9H000 Probable E3 ubiquitin-protein ligase makorin-2 protein 20080626 {GO:0005622=IDA, GO:0003674=ND, GO:0008150=ND, GO:0016567=IEA, GO:0016874=IEA, GO:0008270=IEA, GO:0003676=IEA} biological_process, protein ubiquitination intracellular ligase activity, molecular_function, nucleic acid binding, zinc ion binding Human MKRN3 IntAct UniProtKB {GO:0005515=PMID:22493164, GO:0016567=GO_REF:0000041, GO:0030529=PMID:10196367, GO:0016874=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q13064 Probable E3 ubiquitin-protein ligase makorin-3 protein 20130415 {GO:0005515=IPI, GO:0016567=IEA, GO:0030529=TAS, GO:0016874=IEA, GO:0008270=IEA, GO:0003676=IEA} protein ubiquitination ribonucleoprotein complex ligase activity, nucleic acid binding, protein binding, zinc ion binding Human UniProtKB:O15151 MKS1 UniProtKB UniProtKB {GO:0005515=PMID:17185389, GO:0042384=PMID:19515853, GO:0005737=PMID:17185389, GO:0005813=PMID:19208769, GO:0060271=GO_REF:0000024, GO:0036038=GO_REF:0000024, GO:0005932=PMID:19208769, GO:0048754=GO_REF:0000019} Q9NXB0 Meckel syndrome type 1 protein protein 20120112 {GO:0005515=IPI, GO:0042384=IMP, GO:0005737=IDA, GO:0005813=IDA, GO:0060271=ISS, GO:0036038=ISS, GO:0005932=IDA, GO:0048754=IEA} branching morphogenesis of an epithelial tube, cilium assembly, cilium morphogenesis TCTN-B9D complex, centrosome, cytoplasm, microtubule basal body protein binding Human UniProtKB:Q5SW45 MKX HGNC UniProtKB {GO:0003700=GO_REF:0000002, GO:0000981=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0000122=GO_REF:0000019, GO:0045662=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0010628=GO_REF:0000019, GO:0002932=GO_REF:0000019, GO:0007517=PMID:16408284, GO:0032967=GO_REF:0000019, GO:0035990=GO_REF:0000019, GO:0030199=GO_REF:0000019, GO:0001085=GO_REF:0000019} Q8IYA7 Homeobox protein Mohawk protein 20060405 {GO:0003700=IEA, GO:0000981=IEA, GO:0005634=IEA, GO:0000122=IEA, GO:0045662=IEA, GO:0043565=IEA, GO:0010628=IEA, GO:0002932=IEA, GO:0007517=ISS, GO:0032967=IEA, GO:0035990=IEA, GO:0030199=IEA, GO:0001085=IEA} collagen fibril organization, muscle organ development, negative regulation of myoblast differentiation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of collagen biosynthetic process, positive regulation of gene expression, tendon cell differentiation, tendon sheath development nucleus RNA polymerase II transcription factor binding, sequence-specific DNA binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity Human UniProtKB:Q8BIA3 MLANA PINC UniProtKB {GO:0005802=PMID:12191019, GO:0005515=PMID:15695812, GO:0042470=PMID:15695812, GO:0005794=PMID:15695812, GO:0005887=PMID:8170938, GO:0005789=PMID:15695812} Q16655 Melanoma antigen recognized by T-cells 1 protein 20030904 {GO:0005802=IDA, GO:0005515=IPI, GO:0042470=IDA, GO:0005794=IDA, GO:0005887=TAS, GO:0005789=IDA} Golgi apparatus, endoplasmic reticulum membrane, integral to plasma membrane, melanosome, trans-Golgi network protein binding Human MLC1 UniProtKB UniProtKB {GO:0005515=PMID:22328087, GO:0005215=PMID:11254442, GO:0048471=PMID:22328087, GO:0005886=PMID:22328087, GO:0005783=PMID:22328087, GO:0072584=GO_REF:0000024, GO:0030136=GO_REF:0000024, GO:0005764=GO_REF:0000024, GO:0016323=PMID:18165104, GO:0016324=GO_REF:0000019, GO:0071397=GO_REF:0000024, GO:0005911=GO_REF:0000019, GO:0006810=PMID:11254442, GO:0016192=GO_REF:0000024, GO:0006811=GO_REF:0000037, GO:0032388=PMID:19931615, GO:0031410=GO_REF:0000019, GO:0047484=PMID:22328087, GO:0005901=GO_REF:0000024, GO:0008565=GO_REF:0000024, GO:0045121=GO_REF:0000024, GO:0016021=PMID:17628813, GO:0055037=GO_REF:0000024, GO:0005769=GO_REF:0000024, GO:0005768=PMID:18165104} Q15049 Membrane protein MLC1 protein 20120427 {GO:0005515=IPI, GO:0005215=NAS, GO:0048471=IDA, GO:0005886=IDA, GO:0005783=IDA, GO:0072584=ISS, GO:0030136=ISS, GO:0005764=ISS, GO:0016323=IDA, GO:0016324=IEA, GO:0071397=ISS, GO:0005911=IEA, GO:0006810=NAS, GO:0016192=ISS, GO:0006811=IEA, GO:0032388=IDA, GO:0031410=IEA, GO:0047484=IMP, GO:0005901=ISS, GO:0008565=ISS, GO:0045121=ISS, GO:0016021=IDA, GO:0055037=ISS, GO:0005769=ISS, GO:0005768=IDA} caveolin-mediated endocytosis, cellular response to cholesterol, ion transport, positive regulation of intracellular transport, regulation of response to osmotic stress, transport, vesicle-mediated transport apical plasma membrane, basolateral plasma membrane, caveola, cell-cell junction, clathrin-coated vesicle, cytoplasmic vesicle, early endosome, endoplasmic reticulum, endosome, integral to membrane, lysosome, membrane raft, perinuclear region of cytoplasm, plasma membrane, recycling endosome protein binding, protein transporter activity, transporter activity Human MLEC Reactome UniProtKB {GO:0006457=Reactome:REACT_23878, GO:0005783=GO_REF:0000024, GO:0005789=Reactome:REACT_23850, GO:0030246=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q14165 Malectin protein 20100702 {GO:0006457=TAS, GO:0005783=ISS, GO:0005789=TAS, GO:0030246=ISS, GO:0016021=IEA, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS} cellular protein metabolic process, post-translational protein modification, protein N-linked glycosylation via asparagine, protein folding endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane carbohydrate binding Human MLF1 HPA UniProtKB {GO:0005515=PMID:12176995, GO:0005737=GO_REF:0000052, GO:0019904=PMID:12176995, GO:0007050=PMID:15861129, GO:0005634=GO_REF:0000052, GO:0002318=GO_REF:0000024, GO:0003677=GO_REF:0000024, GO:0006351=GO_REF:0000024} P58340 Myeloid leukemia factor 1 protein 20101115 {GO:0005515=IPI, GO:0005737=IDA, GO:0019904=IDA, GO:0007050=IDA, GO:0005634=IDA, GO:0002318=ISS, GO:0003677=ISS, GO:0006351=ISS} cell cycle arrest, myeloid progenitor cell differentiation, transcription, DNA-dependent cytoplasm, nucleus DNA binding, protein binding, protein domain specific binding Human MLF1IP HPA UniProtKB {GO:0000236=Reactome:REACT_682, GO:0005813=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0006334=Reactome:REACT_22344, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037, GO:0005829=Reactome:REACT_150414, GO:0034080=Reactome:REACT_22186, GO:0005737=GO_REF:0000052, GO:0019048=GO_REF:0000037, GO:0000087=Reactome:REACT_910, GO:0000777=GO_REF:0000039, GO:0005654=Reactome:REACT_22217, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} Q71F23 Centromere protein U protein 20100326 {GO:0000236=TAS, GO:0005813=IDA, GO:0006355=IEA, GO:0006334=TAS, GO:0005634=IDA, GO:0006351=IEA, GO:0005829=TAS, GO:0034080=TAS, GO:0005737=IDA, GO:0019048=IEA, GO:0000087=TAS, GO:0000777=IEA, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS} CENP-A containing nucleosome assembly at centromere, M phase of mitotic cell cycle, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, nucleosome assembly, regulation of transcription, DNA-dependent, transcription, DNA-dependent, virus-host interaction centrosome, condensed chromosome kinetochore, cytoplasm, cytosol, nucleoplasm, nucleus Human MLF2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0006952=PMID:8661158, GO:0005634=GO_REF:0000039} Q15773 Myeloid leukemia factor 2 protein 20040129 {GO:0005737=IEA, GO:0006952=IMP, GO:0005634=IEA} defense response cytoplasm, nucleus Human MLH1 GOC UniProtKB {GO:0005515=PMID:20706999, GO:0032407=PMID:16403449, GO:0030983=GO_REF:0000002, GO:0051257=GO_REF:0000019, GO:0006200=GO_REF:0000033, GO:0048477=GO_REF:0000019, GO:0000239=GO_REF:0000019, GO:0005634=PMID:11809883, GO:0016446=GO_REF:0000033, GO:0007283=GO_REF:0000019, GO:0006303=GO_REF:0000019, GO:0003697=PMID:11809883, GO:0006298=GO_REF:0000033, GO:0016887=GO_REF:0000033, GO:0000289=GO_REF:0000019, GO:0007131=GO_REF:0000033, GO:0032389=GO_REF:0000033, GO:0000795=GO_REF:0000033, GO:0043060=GO_REF:0000019, GO:0008630=GO_REF:0000019, GO:0045190=GO_REF:0000019, GO:0005712=GO_REF:0000033, GO:0005524=GO_REF:0000002, GO:0032300=GO_REF:0000033, GO:0045950=GO_REF:0000019, GO:0032137=GO_REF:0000019, GO:0000712=GO_REF:0000019, GO:0032390=GO_REF:0000033, GO:0007060=GO_REF:0000019, GO:0001673=GO_REF:0000019} P40692 DNA mismatch repair protein Mlh1 protein 20130413 {GO:0005515=IPI, GO:0032407=IDA, GO:0030983=IEA, GO:0051257=IEA, GO:0006200=IBA, GO:0048477=IEA, GO:0000239=IEA, GO:0005634=IC, GO:0016446=IBA, GO:0007283=IEA, GO:0006303=IEA, GO:0003697=IDA, GO:0006298=IBA, GO:0016887=IBA, GO:0000289=IEA, GO:0007131=IBA, GO:0032389=IBA, GO:0000795=IBA, GO:0043060=IEA, GO:0008630=IEA, GO:0045190=IEA, GO:0005712=IBA, GO:0005524=IEA, GO:0032300=IBA, GO:0045950=IEA, GO:0032137=IEA, GO:0000712=IEA, GO:0032390=IBA, GO:0007060=IEA, GO:0001673=IEA} ATP catabolic process, double-strand break repair via nonhomologous end joining, intrinsic apoptotic signaling pathway in response to DNA damage, isotype switching, male meiosis chromosome segregation, meiotic metaphase I plate congression, mismatch repair, negative regulation of mitotic recombination, nuclear-transcribed mRNA poly(A) tail shortening, oogenesis, pachytene, reciprocal meiotic recombination, resolution of meiotic recombination intermediates, somatic hypermutation of immunoglobulin genes, spermatogenesis, spindle midzone assembly involved in meiosis MutLalpha complex, MutLbeta complex, chiasma, male germ cell nucleus, mismatch repair complex, nucleus, synaptonemal complex ATP binding, ATPase activity, MutSalpha complex binding, guanine/thymine mispair binding, mismatched DNA binding, protein binding, single-stranded DNA binding Human PANTHER:PTN000008161 MLH3 GOC UniProtKB {GO:0005515=PMID:20603073, GO:0032407=GO_REF:0000033, GO:0030983=GO_REF:0000002, GO:0000795=GO_REF:0000033, GO:0006200=GO_REF:0000033, GO:0005634=PMID:10615123, GO:0019237=GO_REF:0000019, GO:0005712=GO_REF:0000033, GO:0005524=GO_REF:0000002, GO:0032300=GO_REF:0000033, GO:0007144=GO_REF:0000019, GO:0008104=GO_REF:0000019, GO:0003697=GO_REF:0000033, GO:0003696=PMID:10615123, GO:0003682=GO_REF:0000019, GO:0032390=GO_REF:0000033, GO:0006298=PMID:12095912, GO:0001673=GO_REF:0000019, GO:0007130=GO_REF:0000019, GO:0016887=GO_REF:0000033, GO:0007131=PMID:12095912, GO:0007140=GO_REF:0000019} Q9UHC1 DNA mismatch repair protein Mlh3 protein 20130413 {GO:0005515=IPI, GO:0032407=IBA, GO:0030983=IEA, GO:0000795=IBA, GO:0006200=IBA, GO:0005634=TAS, GO:0019237=IEA, GO:0005712=IBA, GO:0005524=IEA, GO:0032300=IBA, GO:0007144=IEA, GO:0008104=IEA, GO:0003697=IBA, GO:0003696=TAS, GO:0003682=IEA, GO:0032390=IBA, GO:0006298=NAS, GO:0001673=IEA, GO:0007130=IEA, GO:0016887=IBA, GO:0007131=NAS, GO:0007140=IEA} ATP catabolic process, female meiosis I, male meiosis, mismatch repair, protein localization, reciprocal meiotic recombination, synaptonemal complex assembly MutLbeta complex, chiasma, male germ cell nucleus, mismatch repair complex, nucleus, synaptonemal complex ATP binding, ATPase activity, MutSalpha complex binding, centromeric DNA binding, chromatin binding, mismatched DNA binding, protein binding, satellite DNA binding, single-stranded DNA binding Human PANTHER:PTN000008161 MLIP UniProtKB UniProtKB {GO:0016605=GO_REF:0000024, GO:0005635=GO_REF:0000024, GO:0031981=GO_REF:0000024} Q5VWP3 Muscular LMNA-interacting protein protein 20110512 {GO:0016605=ISS, GO:0005635=ISS, GO:0031981=ISS} PML body, nuclear envelope, nuclear lumen Human UniProtKB:Q5FW52 MLKL IntAct UniProtKB {GO:0005515=PMID:22265414, GO:0004672=GO_REF:0000002, GO:0005524=GO_REF:0000002} Q8NB16 Mixed lineage kinase domain-like protein protein 20130415 {GO:0005515=IPI, GO:0004672=IEA, GO:0005524=IEA} ATP binding, protein binding, protein kinase activity Human UniProtKB:Q9Y572 MLL BHF-UCL UniProtKB {GO:0005515=PMID:20541477, GO:0008285=GO_REF:0000019, GO:0003700=PMID:10821850, GO:0006366=PMID:10821850, GO:0044212=PMID:20484083, GO:2001040=PMID:20861184, GO:0080182=PMID:20861184, GO:0032411=PMID:20861184, GO:0005634=PMID:15640349, GO:0009952=GO_REF:0000019, GO:0042800=PMID:15960975, GO:0042803=PMID:11313484, GO:0042802=PMID:11313484, GO:0045322=PMID:16990798, GO:0045944=PMID:20861184, GO:0071339=PMID:15960975, GO:0070577=PMID:19187761, GO:0051569=GO_REF:0000019, GO:0035162=PMID:15618964, GO:0051568=PMID:15960975, GO:0006915=GO_REF:0000037, GO:0003677=GO_REF:0000002, GO:0006306=GO_REF:0000019, GO:0035097=PMID:19556245, GO:0006461=PMID:15199122, GO:0003680=PMID:1423624, GO:0043984=PMID:15960975, GO:0003682=GO_REF:0000019, GO:0008270=PMID:19187761, GO:0045893=PMID:15960975} Q03164 Histone-lysine N-methyltransferase MLL protein 20111205 {GO:0005515=IPI, GO:0008285=IEA, GO:0003700=NAS, GO:0006366=TAS, GO:0044212=IDA, GO:2001040=IMP, GO:0080182=IDA, GO:0032411=IMP, GO:0005634=IDA, GO:0009952=IEA, GO:0042800=IMP, GO:0042803=IDA, GO:0042802=IPI, GO:0045322=IDA, GO:0045944=IDA, GO:0071339=IDA, GO:0070577=IDA, GO:0051569=IEA, GO:0035162=TAS, GO:0051568=IMP, GO:0006915=IEA, GO:0003677=IEA, GO:0006306=IEA, GO:0035097=IDA, GO:0006461=IDA, GO:0003680=NAS, GO:0043984=IMP, GO:0003682=IEA, GO:0008270=IDA, GO:0045893=IMP} DNA methylation, anterior/posterior pattern specification, apoptotic process, embryonic hemopoiesis, histone H3-K4 methylation, histone H3-K4 trimethylation, histone H4-K16 acetylation, negative regulation of cell proliferation, positive regulation of cellular response to drug, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of transporter activity, protein complex assembly, regulation of histone H3-K4 methylation, transcription from RNA polymerase II promoter MLL1 complex, histone methyltransferase complex, nucleus AT DNA binding, DNA binding, chromatin binding, histone acetyl-lysine binding, histone methyltransferase activity (H3-K4 specific), identical protein binding, protein binding, protein homodimerization activity, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding, unmethylated CpG binding, zinc ion binding Human MLL2 IntAct UniProtKB {GO:0005515=PMID:17178841, GO:0006342=GO_REF:0000024, GO:0006355=PMID:9247308, GO:0008284=PMID:16603732, GO:0043627=PMID:16603732, GO:0048477=GO_REF:0000024, GO:0044212=PMID:16603732, GO:0008168=GO_REF:0000038, GO:0001555=GO_REF:0000024, GO:0005634=PMID:9247308, GO:0001701=GO_REF:0000019, GO:0003677=PMID:9247308, GO:0006351=GO_REF:0000037, GO:0018024=GO_REF:0000003, GO:0035097=PMID:14992727, GO:0045944=PMID:16603732, GO:0008270=GO_REF:0000002, GO:0033148=PMID:16603732, GO:0051568=GO_REF:0000024} O14686 Histone-lysine N-methyltransferase MLL2 protein 20130415 {GO:0005515=IPI, GO:0006342=ISS, GO:0006355=NAS, GO:0008284=IMP, GO:0043627=IDA, GO:0048477=ISS, GO:0044212=IDA, GO:0008168=IEA, GO:0001555=ISS, GO:0005634=NAS, GO:0001701=IEA, GO:0003677=NAS, GO:0006351=IEA, GO:0018024=IEA, GO:0035097=IPI, GO:0045944=IMP, GO:0008270=IEA, GO:0033148=IMP, GO:0051568=ISS} chromatin silencing, histone H3-K4 methylation, in utero embryonic development, oocyte growth, oogenesis, positive regulation of cell proliferation, positive regulation of intracellular estrogen receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, response to estrogen stimulus, transcription, DNA-dependent histone methyltransferase complex, nucleus DNA binding, histone-lysine N-methyltransferase activity, methyltransferase activity, protein binding, transcription regulatory region DNA binding, zinc ion binding Human UniProtKB:Q14686 MLL3 GOC UniProtKB {GO:0005515=PMID:17021013, GO:0035556=GO_REF:0000002, GO:0035097=PMID:17500065, GO:0006355=GO_REF:0000037, GO:0016571=GO_REF:0000019, GO:0008168=GO_REF:0000038, GO:0005634=PMID:17500065, GO:0008270=GO_REF:0000002, GO:0042800=PMID:17500065, GO:0003677=GO_REF:0000037, GO:0051568=PMID:17500065, GO:0006351=GO_REF:0000037} Q8NEZ4 Histone-lysine N-methyltransferase MLL3 protein 20130413 {GO:0005515=IPI, GO:0035556=IEA, GO:0035097=IDA, GO:0006355=IEA, GO:0016571=IEA, GO:0008168=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0042800=IDA, GO:0003677=IEA, GO:0051568=IDA, GO:0006351=IEA} histone H3-K4 methylation, histone methylation, intracellular signal transduction, regulation of transcription, DNA-dependent, transcription, DNA-dependent histone methyltransferase complex, nucleus DNA binding, histone methyltransferase activity (H3-K4 specific), methyltransferase activity, protein binding, zinc ion binding Human MLL5 BHF-UCL UniProtKB {GO:0005515=PMID:21423215, GO:0002446=GO_REF:0000024, GO:0071300=PMID:19377461, GO:0003713=PMID:19377461, GO:0042800=PMID:19377461, GO:0006351=GO_REF:0000037, GO:0048384=PMID:19377461, GO:0006306=GO_REF:0000024, GO:0016607=GO_REF:0000039, GO:0070688=PMID:19377461, GO:0030854=PMID:19377461, GO:0030218=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0007050=GO_REF:0000037, GO:0042119=GO_REF:0000024, GO:0019899=PMID:19377461, GO:0045893=PMID:19377461, GO:0051568=PMID:19377461} Q8IZD2 Histone-lysine N-methyltransferase MLL5 protein 20110131 {GO:0005515=IPI, GO:0002446=ISS, GO:0071300=IDA, GO:0003713=IMP, GO:0042800=IDA, GO:0006351=IEA, GO:0048384=IMP, GO:0006306=ISS, GO:0016607=IEA, GO:0070688=IDA, GO:0030854=IMP, GO:0030218=ISS, GO:0008270=IEA, GO:0007050=IEA, GO:0042119=ISS, GO:0019899=IPI, GO:0045893=IMP, GO:0051568=IDA} DNA methylation, cell cycle arrest, cellular response to retinoic acid, erythrocyte differentiation, histone H3-K4 methylation, neutrophil activation, neutrophil mediated immunity, positive regulation of granulocyte differentiation, positive regulation of transcription, DNA-dependent, retinoic acid receptor signaling pathway, transcription, DNA-dependent MLL5-L complex, nuclear speck enzyme binding, histone methyltransferase activity (H3-K4 specific), protein binding, transcription coactivator activity, zinc ion binding Human MLLT1 HPA UniProtKB {GO:0005515=PMID:21729782, GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0006366=PMID:8080983, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006469=GO_REF:0000019, GO:0003677=PMID:7991593} Q03111 Protein ENL protein 20101115 {GO:0005515=IPI, GO:0005737=IDA, GO:0006355=IEA, GO:0006366=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0006469=IEA, GO:0003677=TAS} negative regulation of protein kinase activity, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter cytoplasm, nucleolus, nucleus DNA binding, protein binding Human MLLT10 HPA UniProtKB {GO:0005515=PMID:17868029, GO:0005737=GO_REF:0000052, GO:0003700=PMID:7888665, GO:0045944=PMID:17868029, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q5VX90 Protein AF-10 protein 20080818 {GO:0005515=IPI, GO:0005737=IDA, GO:0003700=NAS, GO:0045944=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, nucleolus, nucleus DNA binding, protein binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human MLLT11 UniProtKB UniProtKB {GO:0005622=PMID:18852119, GO:0003674=GO_REF:0000015, GO:0043065=PMID:18852119, GO:0051901=PMID:18852119, GO:0090200=PMID:18852119, GO:0097191=PMID:18852119, GO:0097193=PMID:18852119} Q13015 Protein AF1q protein 20120327 {GO:0005622=IDA, GO:0003674=ND, GO:0043065=IMP, GO:0051901=IDA, GO:0090200=IDA, GO:0097191=IDA, GO:0097193=IDA} extrinsic apoptotic signaling pathway, intrinsic apoptotic signaling pathway, positive regulation of apoptotic process, positive regulation of mitochondrial depolarization, positive regulation of release of cytochrome c from mitochondria intracellular molecular_function Human MLLT3 IntAct UniProtKB {GO:0005515=PMID:21729782, GO:0006355=GO_REF:0000037, GO:0007379=GO_REF:0000019, GO:2000096=PMID:19591803, GO:0005634=GO_REF:0000039, GO:0009952=GO_REF:0000019, GO:0090090=PMID:19591803, GO:0006351=GO_REF:0000037} P42568 Protein AF-9 protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0007379=IEA, GO:2000096=IGI, GO:0005634=IEA, GO:0009952=IEA, GO:0090090=IGI, GO:0006351=IEA} anterior/posterior pattern specification, negative regulation of canonical Wnt receptor signaling pathway, positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway, regulation of transcription, DNA-dependent, segment specification, transcription, DNA-dependent nucleus protein binding Human UniProtKB:Q9UHB7 MLLT4 HPA UniProtKB {GO:0030054=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0034329=Reactome:REACT_20676, GO:0005730=GO_REF:0000052, GO:0007267=PMID:8242616, GO:0045177=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0008022=PMID:10856295, GO:0045216=Reactome:REACT_19331, GO:0005829=Reactome:REACT_19214, GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0005913=GO_REF:0000019, GO:0005911=PMID:10856295, GO:0007155=GO_REF:0000037, GO:0050839=GO_REF:0000019, GO:0034332=Reactome:REACT_19195} Q5TIG5 Afadin protein 20101115 {GO:0030054=IDA, GO:0005886=IDA, GO:0034329=TAS, GO:0005730=IDA, GO:0007267=TAS, GO:0045177=IEA, GO:0005634=IDA, GO:0008022=TAS, GO:0045216=TAS, GO:0005829=TAS, GO:0007165=IEA, GO:0005737=IDA, GO:0005913=IEA, GO:0005911=TAS, GO:0007155=IEA, GO:0050839=IEA, GO:0034332=TAS} adherens junction organization, cell adhesion, cell junction assembly, cell-cell junction organization, cell-cell signaling, signal transduction apical part of cell, cell junction, cell-cell adherens junction, cell-cell junction, cytoplasm, cytosol, nucleolus, nucleus, plasma membrane cell adhesion molecule binding, protein C-terminus binding Human MLLT6 IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0006355=PMID:8058765, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002} P55198 Protein AF-17 protein 20130415 {GO:0005515=IPI, GO:0006355=TAS, GO:0005634=IEA, GO:0008270=IEA} regulation of transcription, DNA-dependent nucleus protein binding, zinc ion binding Human UniProtKB:Q9NRR5 MLN Reactome UniProtKB {GO:0007186=PMID:10381885, GO:0005179=GO_REF:0000037, GO:0007267=PMID:10381885, GO:0005102=PMID:10381885, GO:0005576=Reactome:REACT_22436} P12872 Promotilin protein 20091022 {GO:0007186=TAS, GO:0005179=IEA, GO:0007267=TAS, GO:0005102=TAS, GO:0005576=TAS} G-protein coupled receptor signaling pathway, cell-cell signaling extracellular region hormone activity, receptor binding Human MLNR Reactome UniProtKB {GO:0005886=Reactome:REACT_22436, GO:0007186=PMID:10381885, GO:0005887=PMID:10381885, GO:0004930=PMID:10381885, GO:0007586=PMID:10381885, GO:0016520=GO_REF:0000002} O43193 Motilin receptor protein 20091019 {GO:0005886=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0004930=TAS, GO:0007586=TAS, GO:0016520=IEA} G-protein coupled receptor signaling pathway, digestion integral to plasma membrane, plasma membrane G-protein coupled receptor activity, growth hormone-releasing hormone receptor activity Human MLPH ENSEMBL UniProtKB {GO:0017137=GO_REF:0000019, GO:0001725=GO_REF:0000019, GO:0005815=GO_REF:0000019, GO:0032400=GO_REF:0000019, GO:0003779=GO_REF:0000019, GO:0030318=GO_REF:0000019, GO:0035371=GO_REF:0000019, GO:0006605=GO_REF:0000019, GO:0006886=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0031489=GO_REF:0000019, GO:0051010=GO_REF:0000019, GO:0030864=GO_REF:0000019} Q9BV36 Melanophilin protein 20130413 {GO:0017137=IEA, GO:0001725=IEA, GO:0005815=IEA, GO:0032400=IEA, GO:0003779=IEA, GO:0030318=IEA, GO:0035371=IEA, GO:0006605=IEA, GO:0006886=IEA, GO:0046872=IEA, GO:0031489=IEA, GO:0051010=IEA, GO:0030864=IEA} intracellular protein transport, melanocyte differentiation, melanosome localization, protein targeting cortical actin cytoskeleton, microtubule organizing center, microtubule plus end, stress fiber Rab GTPase binding, actin binding, metal ion binding, microtubule plus-end binding, myosin V binding Human Ensembl:ENSMUSP00000027528 MLST8 IntAct UniProtKB {GO:0005515=PMID:20562859, GO:0008286=Reactome:REACT_498, GO:0048011=Reactome:REACT_11061, GO:0032008=PMID:15467718, GO:0048015=Reactome:REACT_12464, GO:0031295=Reactome:REACT_19344, GO:0050731=GO_REF:0000019, GO:0005829=Reactome:REACT_147858, GO:0005737=GO_REF:0000024, GO:0032314=GO_REF:0000019, GO:0030838=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9470, GO:0032956=PMID:15467718, GO:0045087=Reactome:REACT_6802} Q9BVC4 Target of rapamycin complex subunit LST8 protein 20130415 {GO:0005515=IPI, GO:0008286=TAS, GO:0048011=TAS, GO:0032008=IMP, GO:0048015=TAS, GO:0031295=TAS, GO:0050731=IEA, GO:0005829=TAS, GO:0005737=ISS, GO:0032314=IEA, GO:0030838=IEA, GO:0007173=TAS, GO:0008543=TAS, GO:0032956=IMP, GO:0045087=TAS} T cell costimulation, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of TOR signaling cascade, positive regulation of actin filament polymerization, positive regulation of peptidyl-tyrosine phosphorylation, regulation of Rac GTPase activity, regulation of actin cytoskeleton organization cytoplasm, cytosol protein binding Human UniProtKB:Q8N122 MLX BHF-UCL UniProtKB {GO:0006355=PMID:10918583, GO:0003700=PMID:10918583, GO:0046982=PMID:11230181, GO:0005634=PMID:10918583, GO:0044281=Reactome:REACT_111217, GO:0003677=PMID:11230181, GO:0006351=GO_REF:0000037, GO:0042803=PMID:11230181, GO:0006913=GO_REF:0000019, GO:0005737=PMID:10918583, GO:0006112=Reactome:REACT_1505, GO:0031325=Reactome:REACT_2122, GO:0046983=GO_REF:0000002, GO:0045892=PMID:11230181, GO:0008134=PMID:11230181} Q9UH92 Max-like protein X protein 20080307 {GO:0006355=NAS, GO:0003700=NAS, GO:0046982=IPI, GO:0005634=IDA, GO:0044281=TAS, GO:0003677=IDA, GO:0006351=IEA, GO:0042803=IPI, GO:0006913=IEA, GO:0005737=IDA, GO:0006112=TAS, GO:0031325=TAS, GO:0046983=IEA, GO:0045892=IDA, GO:0008134=IPI} energy reserve metabolic process, negative regulation of transcription, DNA-dependent, nucleocytoplasmic transport, positive regulation of cellular metabolic process, regulation of transcription, DNA-dependent, small molecule metabolic process, transcription, DNA-dependent cytoplasm, nucleus DNA binding, protein dimerization activity, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding transcription factor activity, transcription factor binding Human UniProtKB:Q9NP71 MLXIP UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005737=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0005741=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0006913=GO_REF:0000019} Q9HAP2 MLX-interacting protein protein 20130413 {GO:0006355=IEA, GO:0005737=IEA, GO:0046983=IEA, GO:0005741=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0006913=IEA} nucleocytoplasmic transport, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, mitochondrial outer membrane, nucleus DNA binding, protein dimerization activity Human UniProtKB-SubCell:SL-0172 MLXIPL BHF-UCL UniProtKB {GO:0071157=PMID:19995986, GO:0008284=PMID:19995986, GO:0003700=PMID:10780788, GO:0070328=PMID:19571538, GO:0005634=PMID:11230181, GO:0090324=PMID:19995986, GO:0044281=Reactome:REACT_111217, GO:0009653=PMID:9860302, GO:0042803=PMID:11230181, GO:0007243=Reactome:REACT_1525, GO:0010255=GO_REF:0000024, GO:0005829=Reactome:REACT_1310, GO:0035538=PMID:18591247, GO:0046889=PMID:19995986, GO:0005737=PMID:11230181, GO:0033137=PMID:19995986, GO:0045944=PMID:11230181, GO:0046983=GO_REF:0000002, GO:0045821=PMID:19995986, GO:0005667=PMID:11230181, GO:0006355=PMID:10780788, GO:0046982=PMID:11230181, GO:0045723=PMID:11230181, GO:0055089=GO_REF:0000024, GO:0042593=PMID:11230181, GO:0000122=GO_REF:0000019, GO:0003677=PMID:11230181, GO:0006351=GO_REF:0000037, GO:0031325=Reactome:REACT_2122, GO:0006112=Reactome:REACT_1505, GO:0042304=Reactome:REACT_1988, GO:0005654=Reactome:REACT_1310, GO:0045893=PMID:11230181, GO:0045892=PMID:11230181, GO:2000505=GO_REF:0000024, GO:0008134=PMID:11230181} Q9NP71 Carbohydrate-responsive element-binding protein protein 20080307 {GO:0071157=IMP, GO:0008284=IMP, GO:0003700=NAS, GO:0070328=NAS, GO:0005634=ISS, GO:0090324=IMP, GO:0044281=TAS, GO:0009653=TAS, GO:0042803=IDA, GO:0007243=TAS, GO:0010255=ISS, GO:0005829=TAS, GO:0035538=TAS, GO:0046889=IMP, GO:0005737=ISS, GO:0033137=IMP, GO:0045944=ISS, GO:0046983=IEA, GO:0045821=IMP, GO:0005667=NAS, GO:0006355=NAS, GO:0046982=IPI, GO:0045723=ISS, GO:0055089=ISS, GO:0042593=ISS, GO:0000122=IEA, GO:0003677=ISS, GO:0006351=IEA, GO:0031325=TAS, GO:0006112=TAS, GO:0042304=TAS, GO:0005654=TAS, GO:0045893=ISS, GO:0045892=ISS, GO:2000505=ISS, GO:0008134=IPI} anatomical structure morphogenesis, energy reserve metabolic process, fatty acid homeostasis, glucose homeostasis, glucose mediated signaling pathway, intracellular protein kinase cascade, negative regulation of cell cycle arrest, negative regulation of oxidative phosphorylation, negative regulation of peptidyl-serine phosphorylation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of cell proliferation, positive regulation of cellular metabolic process, positive regulation of fatty acid biosynthetic process, positive regulation of glycolysis, positive regulation of lipid biosynthetic process, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of energy homeostasis, regulation of fatty acid biosynthetic process, regulation of transcription, DNA-dependent, small molecule metabolic process, transcription, DNA-dependent, triglyceride homeostasis cytoplasm, cytosol, nucleoplasm, nucleus, transcription factor complex DNA binding, carbohydrate response element binding, protein dimerization activity, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding transcription factor activity, transcription factor binding Human UniProtKB:Q99MZ3 MLYCD UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0005737=PMID:10455107, GO:0019395=GO_REF:0000019, GO:0031998=GO_REF:0000019, GO:0005102=PMID:20178365, GO:0050080=PMID:15003260, GO:0006633=PMID:15003260, GO:0006085=PMID:10455107, GO:2001294=PMID:15003260, GO:0010906=PMID:18314420, GO:0005777=PMID:10455107, GO:0005829=GO_REF:0000019} O95822 Malonyl-CoA decarboxylase, mitochondrial protein 20121022 {GO:0005739=IEA, GO:0005737=IDA, GO:0019395=IEA, GO:0031998=IEA, GO:0005102=IPI, GO:0050080=IDA, GO:0006633=IDA, GO:0006085=IDA, GO:2001294=IDA, GO:0010906=IMP, GO:0005777=IDA, GO:0005829=IEA} acetyl-CoA biosynthetic process, fatty acid biosynthetic process, fatty acid oxidation, malonyl-CoA catabolic process, regulation of fatty acid beta-oxidation, regulation of glucose metabolic process cytoplasm, cytosol, mitochondrion, peroxisome malonyl-CoA decarboxylase activity, receptor binding Human MMAA Reactome UniProtKB {GO:0009236=GO_REF:0000041, GO:0017111=GO_REF:0000002, GO:0006635=Reactome:REACT_1473, GO:0005759=Reactome:REACT_19, GO:0019626=Reactome:REACT_993, GO:0044281=Reactome:REACT_111217, GO:0005525=GO_REF:0000037, GO:0044255=Reactome:REACT_22279} Q8IVH4 Methylmalonic aciduria type A protein, mitochondrial protein 20130114 {GO:0009236=IEA, GO:0017111=IEA, GO:0006635=TAS, GO:0005759=TAS, GO:0019626=TAS, GO:0044281=TAS, GO:0005525=IEA, GO:0044255=TAS} cellular lipid metabolic process, cobalamin biosynthetic process, fatty acid beta-oxidation, short-chain fatty acid catabolic process, small molecule metabolic process mitochondrial matrix GTP binding, nucleoside-triphosphatase activity Human MMAB HPA UniProtKB {GO:0009236=GO_REF:0000041, GO:0005739=GO_REF:0000052, GO:0008817=GO_REF:0000003, GO:0005524=GO_REF:0000037} Q96EY8 Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial protein 20110516 {GO:0009236=IEA, GO:0005739=IDA, GO:0008817=IEA, GO:0005524=IEA} cobalamin biosynthetic process mitochondrion ATP binding, cob(I)yrinic acid a,c-diamide adenosyltransferase activity Human MMACHC UniPathway UniProtKB {GO:0009236=GO_REF:0000041, GO:0005739=GO_REF:0000019, GO:0031419=GO_REF:0000037} Q9Y4U1 Methylmalonic aciduria and homocystinuria type C protein protein 20130413 {GO:0009236=IEA, GO:0005739=IEA, GO:0031419=IEA} cobalamin biosynthetic process mitochondrion cobalamin binding Human UniPathway:UPA00148 MMADHC UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0009235=GO_REF:0000002} Q9H3L0 Methylmalonic aciduria and homocystinuria type D protein, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0009235=IEA} cobalamin metabolic process mitochondrion Human UniProtKB-SubCell:SL-0173 MMD PINC UniProtKB {GO:0016020=PMID:7503749, GO:0005887=PMID:7503749, GO:0031902=GO_REF:0000039, GO:0019835=GO_REF:0000002, GO:0004872=PMID:7503749, GO:0016021=GO_REF:0000002, GO:0005765=GO_REF:0000039} Q15546 Monocyte to macrophage differentiation factor protein 20030904 {GO:0016020=TAS, GO:0005887=TAS, GO:0031902=IEA, GO:0019835=IEA, GO:0004872=TAS, GO:0016021=IEA, GO:0005765=IEA} cytolysis integral to membrane, integral to plasma membrane, late endosome membrane, lysosomal membrane, membrane receptor activity Human MME InterPro UniProtKB {GO:0005515=PMID:17342744, GO:0030424=GO_REF:0000024, GO:0005886=Reactome:REACT_147787, GO:0002003=Reactome:REACT_147707, GO:0045202=GO_REF:0000024, GO:0030425=GO_REF:0000024, GO:0005737=PMID:20876573, GO:0006508=GO_REF:0000002, GO:0044306=GO_REF:0000024, GO:0042277=GO_REF:0000024, GO:0001822=PMID:22272689, GO:0071492=PMID:20876573, GO:0071493=PMID:20876573, GO:0046449=PMID:22024547, GO:0050435=GO_REF:0000024, GO:0019233=GO_REF:0000024, GO:0008021=GO_REF:0000024, GO:0004175=PMID:8168535, GO:0016020=GO_REF:0000019, GO:0071345=PMID:20876573, GO:0005887=PMID:2521388, GO:0008270=PMID:8168535, GO:0016021=PMID:2968607, GO:0004222=GO_REF:0000002, GO:0090399=PMID:20876573, GO:0044267=Reactome:REACT_17015, GO:0006518=GO_REF:0000024} Q3KQS6 Membrane metallo-endopeptidase variant 2 protein 20130413 {GO:0005515=IPI, GO:0030424=ISS, GO:0005886=TAS, GO:0002003=TAS, GO:0045202=ISS, GO:0030425=ISS, GO:0005737=IDA, GO:0006508=IEA, GO:0044306=ISS, GO:0042277=ISS, GO:0001822=IEP, GO:0071492=IDA, GO:0071493=IDA, GO:0046449=IMP, GO:0050435=ISS, GO:0019233=ISS, GO:0008021=ISS, GO:0004175=IDA, GO:0016020=IEA, GO:0071345=IDA, GO:0005887=NAS, GO:0008270=IDA, GO:0016021=NAS, GO:0004222=IEA, GO:0090399=IEP, GO:0044267=TAS, GO:0006518=ISS} angiotensin maturation, beta-amyloid metabolic process, cellular protein metabolic process, cellular response to UV-A, cellular response to UV-B, cellular response to cytokine stimulus, creatinine metabolic process, kidney development, peptide metabolic process, proteolysis, replicative senescence, sensory perception of pain axon, cytoplasm, dendrite, integral to membrane, integral to plasma membrane, membrane, neuron projection terminus, plasma membrane, synapse, synaptic vesicle endopeptidase activity, metalloendopeptidase activity, peptide binding, protein binding, zinc ion binding Human InterPro:IPR000718 MMGT1 UniProtKB UniProtKB {GO:0072546=PMID:22119785, GO:0015693=GO_REF:0000024, GO:0005794=GO_REF:0000024, GO:0005886=GO_REF:0000019, GO:0015099=GO_REF:0000019, GO:0015087=GO_REF:0000019, GO:0015095=GO_REF:0000024, GO:0000139=GO_REF:0000039, GO:0005375=GO_REF:0000019, GO:0005384=GO_REF:0000019, GO:0031901=GO_REF:0000039, GO:0016021=PMID:22119785, GO:0005769=GO_REF:0000024} Q8N4V1 Membrane magnesium transporter 1 protein 20120629 {GO:0072546=IDA, GO:0015693=ISS, GO:0005794=ISS, GO:0005886=IEA, GO:0015099=IEA, GO:0015087=IEA, GO:0015095=ISS, GO:0000139=IEA, GO:0005375=IEA, GO:0005384=IEA, GO:0031901=IEA, GO:0016021=IDA, GO:0005769=ISS} magnesium ion transport ER membrane protein complex, Golgi apparatus, Golgi membrane, early endosome, early endosome membrane, integral to membrane, plasma membrane cobalt ion transmembrane transporter activity, copper ion transmembrane transporter activity, magnesium ion transmembrane transporter activity, manganese ion transmembrane transporter activity, nickel cation transmembrane transporter activity Human MMP1 Reactome UniProtKB {GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0007596=Reactome:REACT_604, GO:0019048=GO_REF:0000037, GO:0030574=Reactome:REACT_150401, GO:0005509=GO_REF:0000002, GO:0005578=GO_REF:0000039, GO:0006508=GO_REF:0000037, GO:0005576=Reactome:REACT_150453, GO:0008270=GO_REF:0000002, GO:0050900=Reactome:REACT_12051, GO:0044267=Reactome:REACT_17015} P03956 Interstitial collagenase protein 20120926 {GO:0022617=TAS, GO:0030198=TAS, GO:0007596=TAS, GO:0019048=IEA, GO:0030574=TAS, GO:0005509=IEA, GO:0005578=IEA, GO:0006508=IEA, GO:0005576=TAS, GO:0008270=IEA, GO:0050900=TAS, GO:0044267=TAS} blood coagulation, cellular protein metabolic process, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, leukocyte migration, proteolysis, virus-host interaction extracellular region, proteinaceous extracellular matrix calcium ion binding, zinc ion binding Human MMP10 Reactome UniProtKB {GO:0030334=GO_REF:0000019, GO:0031012=GO_REF:0000002, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0005509=GO_REF:0000002, GO:0005578=GO_REF:0000039, GO:0006508=GO_REF:0000037, GO:0005576=Reactome:REACT_150374, GO:0008270=GO_REF:0000002, GO:0004222=GO_REF:0000002, GO:0005615=PMID:2844164} P09238 Stromelysin-2 protein 20130301 {GO:0030334=IEA, GO:0031012=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0030574=TAS, GO:0005509=IEA, GO:0005578=IEA, GO:0006508=IEA, GO:0005576=TAS, GO:0008270=IEA, GO:0004222=IEA, GO:0005615=TAS} collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, proteolysis, regulation of cell migration extracellular matrix, extracellular region, extracellular space, proteinaceous extracellular matrix calcium ion binding, metalloendopeptidase activity, zinc ion binding Human MMP11 Reactome UniProtKB {GO:0031012=GO_REF:0000002, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0005796=Reactome:REACT_118812, GO:0030574=Reactome:REACT_150401, GO:0005509=GO_REF:0000002, GO:0005578=GO_REF:0000039, GO:0006508=GO_REF:0000037, GO:0005576=Reactome:REACT_150235, GO:0007275=PMID:7746327, GO:0008270=GO_REF:0000002, GO:0004222=GO_REF:0000002} P24347 Stromelysin-3 protein 20130301 {GO:0031012=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0005796=TAS, GO:0030574=TAS, GO:0005509=IEA, GO:0005578=IEA, GO:0006508=IEA, GO:0005576=TAS, GO:0007275=TAS, GO:0008270=IEA, GO:0004222=IEA} collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, multicellular organismal development, proteolysis Golgi lumen, extracellular matrix, extracellular region, proteinaceous extracellular matrix calcium ion binding, metalloendopeptidase activity, zinc ion binding Human MMP12 BHF-UCL UniProtKB {GO:0060054=PMID:15802269, GO:0035313=PMID:15802269, GO:0022617=Reactome:REACT_118572, GO:0004175=PMID:8226919, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0005509=GO_REF:0000002, GO:0005578=GO_REF:0000039, GO:0006508=GO_REF:0000037, GO:0005576=Reactome:REACT_150466, GO:0008270=GO_REF:0000002, GO:0004222=PMID:8226919} P39900 Macrophage metalloelastase protein 20110110 {GO:0060054=IDA, GO:0035313=IDA, GO:0022617=TAS, GO:0004175=TAS, GO:0030198=TAS, GO:0030574=TAS, GO:0005509=IEA, GO:0005578=IEA, GO:0006508=IEA, GO:0005576=TAS, GO:0008270=IEA, GO:0004222=TAS} collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, positive regulation of epithelial cell proliferation involved in wound healing, proteolysis, wound healing, spreading of epidermal cells extracellular region, proteinaceous extracellular matrix calcium ion binding, endopeptidase activity, metalloendopeptidase activity, zinc ion binding Human MMP13 Reactome UniProtKB {GO:0005581=GO_REF:0000038, GO:0051216=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0005578=GO_REF:0000039, GO:0005576=Reactome:REACT_150437, GO:0030282=GO_REF:0000019, GO:0005615=PMID:8207000, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0004222=GO_REF:0000019, GO:0044267=GO_REF:0000019} P45452 Collagenase 3 protein 20130301 {GO:0005581=IEA, GO:0051216=IEA, GO:0005509=IEA, GO:0005578=IEA, GO:0005576=TAS, GO:0030282=IEA, GO:0005615=TAS, GO:0022617=TAS, GO:0030198=TAS, GO:0030574=TAS, GO:0006508=IEA, GO:0008270=IEA, GO:0004222=IEA, GO:0044267=IEA} bone mineralization, cartilage development, cellular protein metabolic process, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, proteolysis collagen, extracellular region, extracellular space, proteinaceous extracellular matrix calcium ion binding, metalloendopeptidase activity, zinc ion binding Human MMP14 Reactome UniProtKB {GO:0005515=PMID:22065321, GO:0043627=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0048771=GO_REF:0000019, GO:0005886=Reactome:REACT_150468, GO:0030307=PMID:22065321, GO:0030324=GO_REF:0000019, GO:0051895=GO_REF:0000019, GO:0005737=PMID:22065321, GO:0001541=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0006508=GO_REF:0000037, GO:0006979=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0042470=GO_REF:0000039, GO:0030335=PMID:22065321, GO:0005796=Reactome:REACT_118753, GO:0005509=GO_REF:0000002, GO:0001525=GO_REF:0000019, GO:0043615=GO_REF:0000019, GO:0009612=GO_REF:0000019, GO:0031012=GO_REF:0000002, GO:0016504=GO_REF:0000019, GO:0005178=GO_REF:0000019, GO:0001503=GO_REF:0000019, GO:0005887=PMID:8015608, GO:0001935=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0048754=GO_REF:0000019, GO:0004222=GO_REF:0000002, GO:0031638=GO_REF:0000019} P50281 Matrix metalloproteinase-14 protein 20130301 {GO:0005515=IPI, GO:0043627=IEA, GO:0003700=IEA, GO:0048771=IEA, GO:0005886=TAS, GO:0030307=IDA, GO:0030324=IEA, GO:0051895=IEA, GO:0005737=IDA, GO:0001541=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0030574=TAS, GO:0006508=IEA, GO:0006979=IEA, GO:0001666=IEA, GO:0042470=IEA, GO:0030335=IDA, GO:0005796=TAS, GO:0005509=IEA, GO:0001525=IEA, GO:0043615=IEA, GO:0009612=IEA, GO:0031012=IEA, GO:0016504=IEA, GO:0005178=IEA, GO:0001503=IEA, GO:0005887=TAS, GO:0001935=IEA, GO:0008270=IEA, GO:0048754=IEA, GO:0004222=IEA, GO:0031638=IEA} angiogenesis, astrocyte cell migration, branching morphogenesis of an epithelial tube, collagen catabolic process, endothelial cell proliferation, extracellular matrix disassembly, extracellular matrix organization, lung development, negative regulation of focal adhesion assembly, ossification, ovarian follicle development, positive regulation of cell growth, positive regulation of cell migration, proteolysis, response to estrogen stimulus, response to hypoxia, response to mechanical stimulus, response to oxidative stress, tissue remodeling, zymogen activation Golgi lumen, cytoplasm, extracellular matrix, integral to plasma membrane, melanosome, plasma membrane calcium ion binding, integrin binding, metalloendopeptidase activity, peptidase activator activity, protein binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human MMP15 GOC UniProtKB {GO:0005515=PMID:15248212, GO:0005886=Reactome:REACT_150439, GO:0005509=GO_REF:0000002, GO:0043085=PMID:7559440, GO:0031012=GO_REF:0000002, GO:0022617=Reactome:REACT_118572, GO:0005887=PMID:7649159, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0004222=GO_REF:0000002, GO:0008047=PMID:7559440, GO:0032355=GO_REF:0000019, GO:0006464=PMID:7559440} P51511 Matrix metalloproteinase-15 protein 20130413 {GO:0005515=IPI, GO:0005886=TAS, GO:0005509=IEA, GO:0043085=TAS, GO:0031012=IEA, GO:0022617=TAS, GO:0005887=TAS, GO:0030198=TAS, GO:0030574=TAS, GO:0006508=IEA, GO:0008270=IEA, GO:0004222=IEA, GO:0008047=TAS, GO:0032355=IEA, GO:0006464=TAS} cellular protein modification process, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, positive regulation of catalytic activity, proteolysis, response to estradiol stimulus extracellular matrix, integral to plasma membrane, plasma membrane calcium ion binding, enzyme activator activity, metalloendopeptidase activity, protein binding, zinc ion binding Human MMP16 GOC UniProtKB {GO:0009986=GO_REF:0000039, GO:0005886=Reactome:REACT_118753, GO:0005796=Reactome:REACT_118753, GO:0005509=GO_REF:0000002, GO:0005578=GO_REF:0000039, GO:0043085=PMID:7559440, GO:0031012=GO_REF:0000002, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0005887=PMID:7559440, GO:0030574=GO_REF:0000037, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0004222=GO_REF:0000002, GO:0008047=PMID:7559440} P51512 Matrix metalloproteinase-16 protein 20130413 {GO:0009986=IEA, GO:0005886=TAS, GO:0005796=TAS, GO:0005509=IEA, GO:0005578=IEA, GO:0043085=TAS, GO:0031012=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0005887=TAS, GO:0030574=IEA, GO:0006508=IEA, GO:0008270=IEA, GO:0004222=IEA, GO:0008047=TAS} collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, positive regulation of catalytic activity, proteolysis Golgi lumen, cell surface, extracellular matrix, integral to plasma membrane, plasma membrane, proteinaceous extracellular matrix calcium ion binding, enzyme activator activity, metalloendopeptidase activity, zinc ion binding Human MMP17 GOC UniProtKB {GO:0031012=GO_REF:0000002, GO:0005887=PMID:8640782, GO:0005509=GO_REF:0000002, GO:0005578=GO_REF:0000039, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0031225=GO_REF:0000037, GO:0043085=PMID:8640782, GO:0008047=PMID:8640782, GO:0004222=GO_REF:0000002, GO:0046872=GO_REF:0000038} Q9ULZ9 Matrix metalloproteinase-17 protein 20130413 {GO:0031012=IEA, GO:0005887=TAS, GO:0005509=IEA, GO:0005578=IEA, GO:0006508=IEA, GO:0008270=IEA, GO:0031225=IEA, GO:0043085=TAS, GO:0008047=TAS, GO:0004222=IEA, GO:0046872=IEA} positive regulation of catalytic activity, proteolysis anchored to membrane, extracellular matrix, integral to plasma membrane, proteinaceous extracellular matrix calcium ion binding, enzyme activator activity, metal ion binding, metalloendopeptidase activity, zinc ion binding Human MMP19 Reactome UniProtKB {GO:0005509=GO_REF:0000002, GO:0005578=PMID:10809722, GO:0001554=GO_REF:0000019, GO:0005576=Reactome:REACT_150387, GO:0001542=GO_REF:0000019, GO:0001525=GO_REF:0000037, GO:0051591=GO_REF:0000019, GO:0030154=GO_REF:0000037, GO:0031012=GO_REF:0000002, GO:0001541=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0006508=PMID:9020145, GO:0008270=GO_REF:0000002, GO:0009725=GO_REF:0000019, GO:0004222=GO_REF:0000002} Q99542 Matrix metalloproteinase-19 protein 20130301 {GO:0005509=IEA, GO:0005578=NAS, GO:0001554=IEA, GO:0005576=TAS, GO:0001542=IEA, GO:0001525=IEA, GO:0051591=IEA, GO:0030154=IEA, GO:0031012=IEA, GO:0001541=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0030574=TAS, GO:0006508=NAS, GO:0008270=IEA, GO:0009725=IEA, GO:0004222=IEA} angiogenesis, cell differentiation, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, luteolysis, ovarian follicle development, ovulation from ovarian follicle, proteolysis, response to cAMP, response to hormone stimulus extracellular matrix, extracellular region, proteinaceous extracellular matrix calcium ion binding, metalloendopeptidase activity, zinc ion binding Human MMP2 IntAct UniProtKB {GO:0005515=PMID:21441952, GO:0005886=GO_REF:0000019, GO:0004252=Reactome:REACT_118723, GO:0005634=GO_REF:0000039, GO:0030017=GO_REF:0000019, GO:0005615=PMID:18492766, GO:0005739=GO_REF:0000039, GO:0071230=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0006508=GO_REF:0000037, GO:0001666=GO_REF:0000019, GO:0007566=GO_REF:0000019, GO:0005578=GO_REF:0000039, GO:0005576=Reactome:REACT_150453, GO:0001525=GO_REF:0000037, GO:0031012=GO_REF:0000002, GO:0060346=GO_REF:0000019, GO:0001957=GO_REF:0000019, GO:0060325=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0004222=GO_REF:0000019, GO:0001955=GO_REF:0000019, GO:0044267=Reactome:REACT_17015} P08253 72 kDa type IV collagenase protein 20130415 {GO:0005515=IPI, GO:0005886=IEA, GO:0004252=TAS, GO:0005634=IEA, GO:0030017=IEA, GO:0005615=IDA, GO:0005739=IEA, GO:0071230=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0030574=TAS, GO:0006508=IEA, GO:0001666=IEA, GO:0007566=IEA, GO:0005578=IEA, GO:0005576=TAS, GO:0001525=IEA, GO:0031012=IEA, GO:0060346=IEA, GO:0001957=IEA, GO:0060325=IEA, GO:0008270=IEA, GO:0004222=IEA, GO:0001955=IEA, GO:0044267=TAS} angiogenesis, blood vessel maturation, bone trabecula formation, cellular protein metabolic process, cellular response to amino acid stimulus, collagen catabolic process, embryo implantation, extracellular matrix disassembly, extracellular matrix organization, face morphogenesis, intramembranous ossification, proteolysis, response to hypoxia extracellular matrix, extracellular region, extracellular space, mitochondrion, nucleus, plasma membrane, proteinaceous extracellular matrix, sarcomere metalloendopeptidase activity, protein binding, serine-type endopeptidase activity, zinc ion binding Human UniProtKB:Q8IX30 MMP20 BHF-UCL UniProtKB {GO:0005515=PMID:18434575, GO:0097186=GO_REF:0000019, GO:0070173=PMID:18434575, GO:0005509=GO_REF:0000002, GO:0005578=GO_REF:0000039, GO:0005576=Reactome:REACT_150437, GO:0005615=PMID:9398237, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0004222=GO_REF:0000002} O60882 Matrix metalloproteinase-20 protein 20081205 {GO:0005515=IPI, GO:0097186=IEA, GO:0070173=TAS, GO:0005509=IEA, GO:0005578=IEA, GO:0005576=TAS, GO:0005615=TAS, GO:0022617=TAS, GO:0030198=TAS, GO:0030574=TAS, GO:0006508=IEA, GO:0008270=IEA, GO:0004222=IEA} amelogenesis, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, proteolysis, regulation of enamel mineralization extracellular region, extracellular space, proteinaceous extracellular matrix calcium ion binding, metalloendopeptidase activity, protein binding, zinc ion binding Human MMP23B UniProtKB UniProtKB {GO:0031012=GO_REF:0000002, GO:0006508=GO_REF:0000038, GO:0008270=GO_REF:0000002, GO:0004222=GO_REF:0000002} H0Y6I4 Matrix metalloproteinase-23, soluble form protein 20130413 {GO:0031012=IEA, GO:0006508=IEA, GO:0008270=IEA, GO:0004222=IEA} proteolysis extracellular matrix metalloendopeptidase activity, zinc ion binding Human UniProtKB-KW:KW-0645 MMP24 GOC UniProtKB {GO:0005887=PMID:10363975, GO:0005509=GO_REF:0000002, GO:0005578=GO_REF:0000039, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0043085=PMID:10363975, GO:0008047=PMID:10363975, GO:0004222=GO_REF:0000002} Q9Y5R2 Matrix metalloproteinase-24 protein 20130413 {GO:0005887=TAS, GO:0005509=IEA, GO:0005578=IEA, GO:0006508=IEA, GO:0008270=IEA, GO:0043085=TAS, GO:0008047=TAS, GO:0004222=IEA} positive regulation of catalytic activity, proteolysis integral to plasma membrane, proteinaceous extracellular matrix calcium ion binding, enzyme activator activity, metalloendopeptidase activity, zinc ion binding Human MMP25 UniProtKB UniProtKB {GO:0006954=PMID:10628838, GO:0016020=PMID:11034316, GO:0009986=PMID:12493773, GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0006508=PMID:10706098, GO:0005578=PMID:10628838, GO:0008270=GO_REF:0000002, GO:0031225=GO_REF:0000037, GO:0004222=GO_REF:0000002, GO:0060022=GO_REF:0000019} Q9NPA2 Matrix metalloproteinase-25 protein 20011005 {GO:0006954=NAS, GO:0016020=NAS, GO:0009986=IDA, GO:0005886=IEA, GO:0005509=IEA, GO:0006508=NAS, GO:0005578=NAS, GO:0008270=IEA, GO:0031225=IEA, GO:0004222=IEA, GO:0060022=IEA} hard palate development, inflammatory response, proteolysis anchored to membrane, cell surface, membrane, plasma membrane, proteinaceous extracellular matrix calcium ion binding, metalloendopeptidase activity, zinc ion binding Human MMP26 UniProtKB UniProtKB {GO:0030574=GO_REF:0000037, GO:0005578=PMID:10801841, GO:0006508=PMID:10987280, GO:0008270=GO_REF:0000002, GO:0004222=GO_REF:0000002} Q9NRE1 Matrix metalloproteinase-26 protein 20011005 {GO:0030574=IEA, GO:0005578=NAS, GO:0006508=NAS, GO:0008270=IEA, GO:0004222=IEA} collagen catabolic process, proteolysis proteinaceous extracellular matrix metalloendopeptidase activity, zinc ion binding Human MMP28 UniProtKB UniProtKB {GO:0005509=GO_REF:0000002, GO:0005578=PMID:11121398, GO:0006508=GO_REF:0000029, GO:0008270=GO_REF:0000002, GO:0004222=PMID:11121398, GO:0008237=GO_REF:0000002} Q9H239 Matrix metalloproteinase-28 protein 20020606 {GO:0005509=IEA, GO:0005578=NAS, GO:0006508=NAS, GO:0008270=IEA, GO:0004222=TAS, GO:0008237=IEA} proteolysis proteinaceous extracellular matrix calcium ion binding, metalloendopeptidase activity, metallopeptidase activity, zinc ion binding Human MMP3 HPA UniProtKB {GO:0030334=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0005578=GO_REF:0000039, GO:0005576=Reactome:REACT_150416, GO:0005615=PMID:3360803, GO:0046872=GO_REF:0000038, GO:0043231=GO_REF:0000052, GO:0071230=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0004222=GO_REF:0000002} P08254 Stromelysin-1 protein 20080205 {GO:0030334=IEA, GO:0005509=IEA, GO:0005578=IEA, GO:0005576=TAS, GO:0005615=TAS, GO:0046872=IEA, GO:0043231=IDA, GO:0071230=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0030574=TAS, GO:0006508=IEA, GO:0008270=IEA, GO:0004222=IEA} cellular response to amino acid stimulus, collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, proteolysis, regulation of cell migration extracellular region, extracellular space, intracellular membrane-bounded organelle, proteinaceous extracellular matrix calcium ion binding, metal ion binding, metalloendopeptidase activity, zinc ion binding Human MMP7 Reactome UniProtKB {GO:0050830=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0005578=GO_REF:0000039, GO:0005576=Reactome:REACT_150437, GO:0005615=PMID:1497627, GO:0050829=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0042127=GO_REF:0000019, GO:0030574=Reactome:REACT_150401, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0004222=GO_REF:0000002, GO:0002779=GO_REF:0000019} P09237 Matrilysin protein 20130301 {GO:0050830=IEA, GO:0042493=IEA, GO:0005578=IEA, GO:0005576=TAS, GO:0005615=TAS, GO:0050829=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0042127=IEA, GO:0030574=TAS, GO:0006508=IEA, GO:0008270=IEA, GO:0004222=IEA, GO:0002779=IEA} antibacterial peptide secretion, collagen catabolic process, defense response to Gram-negative bacterium, defense response to Gram-positive bacterium, extracellular matrix disassembly, extracellular matrix organization, proteolysis, regulation of cell proliferation, response to drug extracellular region, extracellular space, proteinaceous extracellular matrix metalloendopeptidase activity, zinc ion binding Human MMP8 Reactome UniProtKB {GO:0031012=GO_REF:0000002, GO:0022617=Reactome:REACT_118572, GO:0004252=PMID:2164002, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0005509=GO_REF:0000002, GO:0005578=GO_REF:0000039, GO:0006508=PMID:2164002, GO:0005576=Reactome:REACT_150397, GO:0008270=PMID:2164002, GO:0004222=GO_REF:0000002, GO:0005615=PMID:2164002} P22894 Neutrophil collagenase protein 20130301 {GO:0031012=IEA, GO:0022617=TAS, GO:0004252=IDA, GO:0030198=TAS, GO:0030574=TAS, GO:0005509=IEA, GO:0005578=IEA, GO:0006508=IDA, GO:0005576=TAS, GO:0008270=TAS, GO:0004222=IEA, GO:0005615=IDA} collagen catabolic process, extracellular matrix disassembly, extracellular matrix organization, proteolysis extracellular matrix, extracellular region, extracellular space, proteinaceous extracellular matrix calcium ion binding, metalloendopeptidase activity, serine-type endopeptidase activity, zinc ion binding Human MMP9 BHF-UCL UniProtKB {GO:0005515=PMID:21441952, GO:0043065=GO_REF:0000019, GO:0051549=PMID:17704059, GO:0007566=GO_REF:0000019, GO:0005518=PMID:2251898, GO:0005578=GO_REF:0000039, GO:0005576=Reactome:REACT_150437, GO:0005615=PMID:2251898, GO:0001501=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0030574=Reactome:REACT_150401, GO:0006508=PMID:2551898, GO:0030225=PMID:2251898, GO:0008270=PMID:2251898, GO:0004222=PMID:9789069} P14780 Matrix metalloproteinase-9 protein 20081118 {GO:0005515=IPI, GO:0043065=IEA, GO:0051549=IMP, GO:0007566=IEA, GO:0005518=TAS, GO:0005578=IEA, GO:0005576=TAS, GO:0005615=IDA, GO:0001501=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0030574=TAS, GO:0006508=IDA, GO:0030225=TAS, GO:0008270=TAS, GO:0004222=IDA} collagen catabolic process, embryo implantation, extracellular matrix disassembly, extracellular matrix organization, macrophage differentiation, positive regulation of apoptotic process, positive regulation of keratinocyte migration, proteolysis, skeletal system development extracellular region, extracellular space, proteinaceous extracellular matrix collagen binding, metalloendopeptidase activity, protein binding, zinc ion binding Human MMRN1 Reactome UniProtKB {GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0030168=Reactome:REACT_798, GO:0031093=Reactome:REACT_21351, GO:0005576=Reactome:REACT_21351, GO:0007155=PMID:9189649} Q13201 Multimerin-1 protein 20130213 {GO:0007596=TAS, GO:0002576=TAS, GO:0030168=TAS, GO:0031093=TAS, GO:0005576=TAS, GO:0007155=TAS} blood coagulation, cell adhesion, platelet activation, platelet degranulation extracellular region, platelet alpha granule lumen Human MMRN2 UniProtKB UniProtKB {GO:0030948=PMID:22020326, GO:0005515=PMID:22020326, GO:0090051=PMID:22020326, GO:0001525=GO_REF:0000037, GO:0005615=PMID:11559704, GO:0005604=GO_REF:0000019} Q9H8L6 Multimerin-2 protein 20121008 {GO:0030948=IDA, GO:0005515=IPI, GO:0090051=IDA, GO:0001525=IEA, GO:0005615=IDA, GO:0005604=IEA} angiogenesis, negative regulation of cell migration involved in sprouting angiogenesis, negative regulation of vascular endothelial growth factor receptor signaling pathway basement membrane, extracellular space protein binding Human MMS19 Reactome UniProtKB {GO:0005515=PMID:20797633, GO:0016226=PMID:22678361, GO:0030331=PMID:11279242, GO:0003713=PMID:11279242, GO:0005819=PMID:20797633, GO:0030159=PMID:11279242, GO:0005634=PMID:20797633, GO:0044281=Reactome:REACT_111217, GO:0006259=PMID:22678361, GO:0006974=PMID:22678362, GO:0006351=PMID:11071939, GO:0000160=PMID:11279242, GO:0005737=PMID:22678361, GO:0006281=PMID:22678362, GO:0007059=PMID:20797633, GO:0097361=PMID:22678361, GO:0006289=PMID:11279242, GO:0009725=PMID:11279242, GO:0045893=PMID:11279242, GO:0030674=PMID:11279242, GO:0005675=PMID:11279242, GO:0071817=PMID:20797633} Q96T76 MMS19 nucleotide excision repair protein homolog protein 20120307 {GO:0005515=IPI, GO:0016226=IMP, GO:0030331=IPI, GO:0003713=IMP, GO:0005819=IDA, GO:0030159=NAS, GO:0005634=IDA, GO:0044281=TAS, GO:0006259=IMP, GO:0006974=IMP, GO:0006351=NAS, GO:0000160=NAS, GO:0005737=IDA, GO:0006281=IMP, GO:0007059=IMP, GO:0097361=IDA, GO:0006289=NAS, GO:0009725=NAS, GO:0045893=IMP, GO:0030674=NAS, GO:0005675=NAS, GO:0071817=IDA} DNA metabolic process, DNA repair, chromosome segregation, iron-sulfur cluster assembly, nucleotide-excision repair, phosphorelay signal transduction system, positive regulation of transcription, DNA-dependent, response to DNA damage stimulus, response to hormone stimulus, small molecule metabolic process, transcription, DNA-dependent CIA complex, MMXD complex, cytoplasm, holo TFIIH complex, nucleus, spindle estrogen receptor binding, protein binding, protein binding, bridging, receptor signaling complex scaffold activity, transcription coactivator activity Human MMS22L UniProtKB UniProtKB {GO:0005515=PMID:21055984, GO:0042555=PMID:21055985, GO:0035101=PMID:21055985, GO:0000724=PMID:21055983, GO:0031297=PMID:21055983, GO:0043596=PMID:21055983} Q6ZRQ5 Protein MMS22-like protein 20101123 {GO:0005515=IPI, GO:0042555=IDA, GO:0035101=IDA, GO:0000724=IMP, GO:0031297=IMP, GO:0043596=IDA} double-strand break repair via homologous recombination, replication fork processing FACT complex, MCM complex, nuclear replication fork protein binding Human MN1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0001957=GO_REF:0000019, GO:0005575=GO_REF:0000015} Q10571 Probable tumor suppressor protein MN1 protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0001957=IEA, GO:0005575=ND} biological_process, intramembranous ossification cellular_component molecular_function Human MNAT1 GOC UniProtKB {GO:0005515=PMID:8692842, GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006368=Reactome:REACT_2089, GO:0006367=Reactome:REACT_1851, GO:0006366=Reactome:REACT_1366, GO:0008283=PMID:8521818, GO:0006363=Reactome:REACT_1074, GO:0006362=Reactome:REACT_2204, GO:0006361=Reactome:REACT_1974, GO:0006360=Reactome:REACT_1309, GO:0005634=GO_REF:0000052, GO:0000079=PMID:8521818, GO:0007512=GO_REF:0000019, GO:0043231=GO_REF:0000052, GO:0000084=Reactome:REACT_899, GO:0000082=Reactome:REACT_1783, GO:0005737=GO_REF:0000052, GO:0000086=Reactome:REACT_2203, GO:0045944=PMID:8692842, GO:0016032=Reactome:REACT_6256, GO:0044236=GO_REF:0000019, GO:0000080=Reactome:REACT_1590, GO:0008094=PMID:9852112, GO:0043066=GO_REF:0000019, GO:0006355=GO_REF:0000019, GO:0006357=PMID:10801852, GO:0006370=Reactome:REACT_1470, GO:0006915=GO_REF:0000019, GO:0048661=GO_REF:0000019, GO:0008353=PMID:9852112, GO:0050434=Reactome:REACT_6162, GO:0051592=GO_REF:0000019, GO:0050790=GO_REF:0000019, GO:0007049=GO_REF:0000002, GO:0004672=PMID:9852112, GO:0047485=PMID:11445587, GO:0006461=PMID:8521818, GO:0006281=Reactome:REACT_216, GO:0006283=Reactome:REACT_1628, GO:0021591=GO_REF:0000019, GO:0006468=PMID:9852112, GO:0005654=Reactome:REACT_1584, GO:0008270=GO_REF:0000002, GO:0006289=Reactome:REACT_1826, GO:0000718=Reactome:REACT_311, GO:0000278=Reactome:REACT_152, GO:0005675=PMID:9852112} P51948 CDK-activating kinase assembly factor MAT1 protein 20130413 {GO:0005515=IPI, GO:0022415=TAS, GO:0010467=TAS, GO:0006368=TAS, GO:0006367=TAS, GO:0006366=TAS, GO:0008283=TAS, GO:0006363=TAS, GO:0006362=TAS, GO:0006361=TAS, GO:0006360=TAS, GO:0005634=IDA, GO:0000079=TAS, GO:0007512=IEA, GO:0043231=IDA, GO:0000084=TAS, GO:0000082=TAS, GO:0005737=IDA, GO:0000086=TAS, GO:0045944=IMP, GO:0016032=TAS, GO:0044236=IEA, GO:0000080=TAS, GO:0008094=IDA, GO:0043066=IEA, GO:0006355=IEA, GO:0006357=IDA, GO:0006370=TAS, GO:0006915=IEA, GO:0048661=IEA, GO:0008353=IDA, GO:0050434=TAS, GO:0051592=IEA, GO:0050790=IEA, GO:0007049=IEA, GO:0004672=IDA, GO:0047485=IPI, GO:0006461=TAS, GO:0006281=TAS, GO:0006283=TAS, GO:0021591=IEA, GO:0006468=IDA, GO:0005654=TAS, GO:0008270=IEA, GO:0006289=TAS, GO:0000718=TAS, GO:0000278=TAS, GO:0005675=IDA} 7-methylguanosine mRNA capping, DNA repair, G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, G2/M transition of mitotic cell cycle, S phase of mitotic cell cycle, adult heart development, apoptotic process, cell cycle, cell proliferation, gene expression, mitotic cell cycle, multicellular organismal metabolic process, negative regulation of apoptotic process, nucleotide-excision repair, nucleotide-excision repair, DNA damage removal, positive regulation of smooth muscle cell proliferation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of viral transcription, protein complex assembly, protein phosphorylation, regulation of catalytic activity, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, response to calcium ion, termination of RNA polymerase I transcription, transcription elongation from RNA polymerase I promoter, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase I promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase I promoter, transcription initiation from RNA polymerase II promoter, transcription-coupled nucleotide-excision repair, ventricular system development, viral reproduction, viral reproductive process cytoplasm, holo TFIIH complex, intracellular membrane-bounded organelle, nucleoplasm, nucleus DNA-dependent ATPase activity, RNA polymerase II carboxy-terminal domain kinase activity, protein N-terminus binding, protein binding, protein kinase activity, zinc ion binding Human MND1 UniProtKB UniProtKB {GO:0007126=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006310=GO_REF:0000037, GO:0003677=GO_REF:0000037} Q9BWT6 Meiotic nuclear division protein 1 homolog protein 20130413 {GO:0007126=IEA, GO:0005634=IEA, GO:0006310=IEA, GO:0003677=IEA} DNA recombination, meiosis nucleus DNA binding Human UniProtKB-SubCell:SL-0191 MNDA HPA UniProtKB {GO:0050853=PMID:17875758, GO:0005737=GO_REF:0000052, GO:0006968=PMID:1644857, GO:0006355=GO_REF:0000037, GO:0043065=PMID:17875758, GO:0005730=GO_REF:0000052, GO:0030889=PMID:17875758, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0006974=PMID:17875758, GO:0006351=GO_REF:0000037, GO:0043231=GO_REF:0000052} P41218 Myeloid cell nuclear differentiation antigen protein 20101115 {GO:0050853=IMP, GO:0005737=IDA, GO:0006968=TAS, GO:0006355=IEA, GO:0043065=IMP, GO:0005730=IDA, GO:0030889=IMP, GO:0005634=IDA, GO:0003677=IEA, GO:0006974=IMP, GO:0006351=IEA, GO:0043231=IDA} B cell receptor signaling pathway, cellular defense response, negative regulation of B cell proliferation, positive regulation of apoptotic process, regulation of transcription, DNA-dependent, response to DNA damage stimulus, transcription, DNA-dependent cytoplasm, intracellular membrane-bounded organelle, nucleolus, nucleus DNA binding Human MNS1 ENSEMBL UniProtKB {GO:0005882=GO_REF:0000019, GO:0007126=GO_REF:0000037, GO:0005635=GO_REF:0000019} Q8NEH6 Meiosis-specific nuclear structural protein 1 protein 20130413 {GO:0005882=IEA, GO:0007126=IEA, GO:0005635=IEA} meiosis intermediate filament, nuclear envelope Human Ensembl:ENSMUSP00000034746 MNT PINC UniProtKB {GO:0003700=GO_REF:0000019, GO:0008285=PMID:9184233, GO:0006366=PMID:9184233, GO:0007569=GO_REF:0000019, GO:0003714=PMID:9598315, GO:0003713=PMID:9598315, GO:0042981=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0007275=PMID:9184233, GO:0003677=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0051726=GO_REF:0000019} Q99583 Max-binding protein MNT protein 20030904 {GO:0003700=IEA, GO:0008285=TAS, GO:0006366=TAS, GO:0007569=IEA, GO:0003714=TAS, GO:0003713=TAS, GO:0042981=IEA, GO:0005634=IEA, GO:0007275=TAS, GO:0003677=IEA, GO:0003682=IEA, GO:0046983=IEA, GO:0051726=IEA} cell aging, multicellular organismal development, negative regulation of cell proliferation, regulation of apoptotic process, regulation of cell cycle, transcription from RNA polymerase II promoter nucleus DNA binding, chromatin binding, protein dimerization activity, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, transcription corepressor activity Human MNX1 PINC UniProtKB {GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000029, GO:0006357=PMID:9843207, GO:0021520=GO_REF:0000019, GO:0005634=GO_REF:0000029, GO:0021675=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0009653=PMID:9843207, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0008045=GO_REF:0000019, GO:0006959=PMID:7914194, GO:0031018=GO_REF:0000019, GO:0060539=GO_REF:0000019, GO:0021904=GO_REF:0000019, GO:0001764=GO_REF:0000019} P50219 Motor neuron and pancreas homeobox protein 1 protein 20031119 {GO:0006355=NAS, GO:0003700=NAS, GO:0006357=TAS, GO:0021520=IEA, GO:0005634=NAS, GO:0021675=IEA, GO:0009791=IEA, GO:0009653=TAS, GO:0006351=IEA, GO:0043565=IEA, GO:0008045=IEA, GO:0006959=TAS, GO:0031018=IEA, GO:0060539=IEA, GO:0021904=IEA, GO:0001764=IEA} anatomical structure morphogenesis, diaphragm development, dorsal/ventral neural tube patterning, endocrine pancreas development, humoral immune response, motor neuron axon guidance, nerve development, neuron migration, post-embryonic development, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, spinal cord motor neuron cell fate specification, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human MOAP1 BHF-UCL UniProtKB {GO:0005515=PMID:11060313, GO:0005737=GO_REF:0000054, GO:0030262=PMID:11060313, GO:0006919=PMID:11060313, GO:0006921=PMID:11060313, GO:0042803=PMID:11060313} Q96BY2 Modulator of apoptosis 1 protein 20090626 {GO:0005515=IPI, GO:0005737=IDA, GO:0030262=IDA, GO:0006919=IDA, GO:0006921=IDA, GO:0042803=IPI} activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic nuclear changes, cellular component disassembly involved in execution phase of apoptosis cytoplasm protein binding, protein homodimerization activity Human MOB1A IntAct UniProtKB {GO:0005515=PMID:19739119, GO:0035329=Reactome:REACT_118607, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_118858} Q9H8S9 MOB kinase activator 1A protein 20130415 {GO:0005515=IPI, GO:0035329=TAS, GO:0046872=IEA, GO:0005829=TAS} hippo signaling cascade cytosol metal ion binding, protein binding Human UniProtKB:Q9NRM7 MOB1B GOC UniProtKB {GO:0005515=PMID:19739119, GO:0019209=PMID:15197186, GO:0005737=PMID:15067004, GO:0046777=PMID:15197186, GO:0005634=PMID:15067004, GO:0035329=Reactome:REACT_118607, GO:0019900=PMID:15197186, GO:0046872=GO_REF:0000037, GO:0042327=PMID:15197186, GO:0005829=Reactome:REACT_118858} Q7L9L4 MOB kinase activator 1B protein 20130413 {GO:0005515=IPI, GO:0019209=IDA, GO:0005737=IDA, GO:0046777=IDA, GO:0005634=IDA, GO:0035329=TAS, GO:0019900=IPI, GO:0046872=IEA, GO:0042327=IDA, GO:0005829=TAS} hippo signaling cascade, positive regulation of phosphorylation, protein autophosphorylation cytoplasm, cytosol, nucleus kinase activator activity, kinase binding, metal ion binding, protein binding Human MOB2 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0048471=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0046872=GO_REF:0000037} Q70IA6 MOB kinase activator 2 protein 20111111 {GO:0005737=IDA, GO:0048471=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0046872=IEA} cytoplasm, nucleolus, nucleus, perinuclear region of cytoplasm metal ion binding Human MOB3A LIFEdb UniProtKB {GO:0005622=GO_REF:0000054, GO:0046872=GO_REF:0000037} Q96BX8 MOB kinase activator 3A protein 20100607 {GO:0005622=IDA, GO:0046872=IEA} intracellular metal ion binding Human MOB3B IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0046872=GO_REF:0000037} Q86TA1 MOB kinase activator 3B protein 20130415 {GO:0005515=IPI, GO:0046872=IEA} metal ion binding, protein binding Human UniProtKB:P49902 MOB3C UniProtKB UniProtKB {GO:0046872=GO_REF:0000037} Q70IA8 MOB kinase activator 3C protein 20130413 {GO:0046872=IEA} metal ion binding Human UniProtKB-KW:KW-0479 MOB4 IntAct UniProtKB {GO:0005515=PMID:19156129, GO:0005737=GO_REF:0000024, GO:0048471=GO_REF:0000039, GO:0005794=PMID:11251078, GO:0016020=GO_REF:0000019, GO:0032580=GO_REF:0000039, GO:0006810=GO_REF:0000037, GO:0019900=GO_REF:0000019, GO:0046872=GO_REF:0000037} Q9Y3A3 MOB-like protein phocein protein 20130415 {GO:0005515=IPI, GO:0005737=ISS, GO:0048471=IEA, GO:0005794=IDA, GO:0016020=IEA, GO:0032580=IEA, GO:0006810=IEA, GO:0019900=IEA, GO:0046872=IEA} transport Golgi apparatus, Golgi cisterna membrane, cytoplasm, membrane, perinuclear region of cytoplasm kinase binding, metal ion binding, protein binding Human UniProtKB:Q9P2B4 MOBP HPA UniProtKB {GO:0005739=GO_REF:0000019, GO:0048471=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0019911=GO_REF:0000019, GO:0043231=GO_REF:0000052, GO:0007399=GO_REF:0000002} Q13875 Myelin-associated oligodendrocyte basic protein protein 20101115 {GO:0005739=IEA, GO:0048471=IEA, GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0019911=IEA, GO:0043231=IDA, GO:0007399=IEA} nervous system development cytoplasm, intracellular membrane-bounded organelle, mitochondrion, nucleolus, nucleus, perinuclear region of cytoplasm structural constituent of myelin sheath Human MOCOS Reactome UniProtKB {GO:0032324=Reactome:REACT_25073, GO:0043545=PMID:11302742, GO:0006766=Reactome:REACT_11193, GO:0006777=GO_REF:0000037, GO:0030170=GO_REF:0000002, GO:0006767=Reactome:REACT_11238, GO:0044281=Reactome:REACT_111217, GO:0005575=GO_REF:0000015, GO:0008265=Reactome:REACT_25122, GO:0016740=GO_REF:0000037, GO:0005829=Reactome:REACT_25122, GO:0030151=GO_REF:0000002} Q96EN8 Molybdenum cofactor sulfurase protein 20100908 {GO:0032324=TAS, GO:0043545=IMP, GO:0006766=TAS, GO:0006777=IEA, GO:0030170=IEA, GO:0006767=TAS, GO:0044281=TAS, GO:0005575=ND, GO:0008265=TAS, GO:0016740=IEA, GO:0005829=TAS, GO:0030151=IEA} Mo-molybdopterin cofactor biosynthetic process, molybdopterin cofactor biosynthetic process, molybdopterin cofactor metabolic process, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cellular_component, cytosol Mo-molybdopterin cofactor sulfurase activity, molybdenum ion binding, pyridoxal phosphate binding, transferase activity Human MOCS1 Reactome UniProtKB {GO:0051539=GO_REF:0000037, GO:0006767=Reactome:REACT_11238, GO:0005634=PMID:9731530, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0016829=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_25068, GO:0032324=Reactome:REACT_25073, GO:0006766=Reactome:REACT_11193, GO:0006777=PMID:9921896, GO:0019008=GO_REF:0000002} Q9NZB8 Molybdenum cofactor biosynthesis protein 1 protein 20100908 {GO:0051539=IEA, GO:0006767=TAS, GO:0005634=NAS, GO:0044281=TAS, GO:0003824=IEA, GO:0005525=IEA, GO:0016829=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0032324=TAS, GO:0006766=TAS, GO:0006777=IMP, GO:0019008=IEA} Mo-molybdopterin cofactor biosynthetic process, molybdopterin cofactor biosynthetic process, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cytosol, molybdopterin synthase complex, nucleus 4 iron, 4 sulfur cluster binding, GTP binding, catalytic activity, lyase activity, metal ion binding Human MOCS2 Reactome UniProtKB {GO:0006767=Reactome:REACT_11238, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0042802=GO_REF:0000019, GO:0005829=Reactome:REACT_25353, GO:0030366=PMID:15073332, GO:0032324=Reactome:REACT_25073, GO:0005737=GO_REF:0000052, GO:0000166=GO_REF:0000037, GO:0006766=Reactome:REACT_11193, GO:0006777=PMID:12732628, GO:0019008=PMID:12732628, GO:0016740=GO_REF:0000037} O96033 Molybdopterin synthase sulfur carrier subunit protein 20100908 {GO:0006767=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0042802=IEA, GO:0005829=TAS, GO:0030366=IDA, GO:0032324=TAS, GO:0005737=IDA, GO:0000166=IEA, GO:0006766=TAS, GO:0006777=IDA, GO:0019008=IPI, GO:0016740=IEA} Mo-molybdopterin cofactor biosynthetic process, molybdopterin cofactor biosynthetic process, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cytoplasm, cytosol, molybdopterin synthase complex, nucleus Mo-molybdopterin synthase activity, identical protein binding, nucleotide binding, transferase activity Human MOCS3 Reactome UniProtKB {GO:0005515=PMID:18650437, GO:0016779=PMID:19017811, GO:0006767=Reactome:REACT_11238, GO:0034227=PMID:19017811, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_25006, GO:0032324=Reactome:REACT_25073, GO:0016783=Reactome:REACT_25006, GO:0002098=PMID:19017811, GO:0018192=PMID:15910006, GO:0006766=Reactome:REACT_11193, GO:0006777=PMID:15073332, GO:0004792=PMID:17459099, GO:0042292=PMID:19017811} O95396 Adenylyltransferase and sulfurtransferase MOCS3 protein 20100908 {GO:0005515=IPI, GO:0016779=IDA, GO:0006767=TAS, GO:0034227=IDA, GO:0044281=TAS, GO:0005524=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0032324=TAS, GO:0016783=TAS, GO:0002098=IDA, GO:0018192=IDA, GO:0006766=TAS, GO:0006777=IDA, GO:0004792=IMP, GO:0042292=IDA} Mo-molybdopterin cofactor biosynthetic process, enzyme active site formation via L-cysteine persulfide, molybdopterin cofactor biosynthetic process, small molecule metabolic process, tRNA thio-modification, tRNA wobble uridine modification, vitamin metabolic process, water-soluble vitamin metabolic process cytosol ATP binding, URM1 activating enzyme activity, metal ion binding, nucleotidyltransferase activity, protein binding, sulfurtransferase activity, thiosulfate sulfurtransferase activity Human MOG UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0034126=GO_REF:0000024, GO:0016021=GO_REF:0000038, GO:0007417=PMID:1373175, GO:0007155=GO_REF:0000037} Q5SUK5 Myelin-oligodendrocyte glycoprotein protein 20130413 {GO:0005886=IEA, GO:0034126=ISS, GO:0016021=IEA, GO:0007417=TAS, GO:0007155=IEA} cell adhesion, central nervous system development, positive regulation of MyD88-dependent toll-like receptor signaling pathway integral to membrane, plasma membrane Human UniProtKB-KW:KW-0812 MOGAT2 MGI UniProtKB {GO:0050892=GO_REF:0000019, GO:0005783=PMID:14966132, GO:0019432=GO_REF:0000041, GO:0005789=GO_REF:0000039, GO:0003846=GO_REF:0000003, GO:0016407=GO_REF:0000019, GO:0006651=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0006071=GO_REF:0000037} Q3SYC2 2-acylglycerol O-acyltransferase 2 protein 20091109 {GO:0050892=IEA, GO:0005783=IDA, GO:0019432=IEA, GO:0005789=IEA, GO:0003846=IEA, GO:0016407=IEA, GO:0006651=IEA, GO:0016021=IEA, GO:0006071=IEA} diacylglycerol biosynthetic process, glycerol metabolic process, intestinal absorption, triglyceride biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane 2-acylglycerol O-acyltransferase activity, acetyltransferase activity Human MOGAT3 UniPathway UniProtKB {GO:0019432=GO_REF:0000041, GO:0005789=GO_REF:0000039, GO:0003846=GO_REF:0000003, GO:0004144=GO_REF:0000003, GO:0016021=GO_REF:0000037, GO:0006071=GO_REF:0000037} Q86VF5 2-acylglycerol O-acyltransferase 3 protein 20130413 {GO:0019432=IEA, GO:0005789=IEA, GO:0003846=IEA, GO:0004144=IEA, GO:0016021=IEA, GO:0006071=IEA} glycerol metabolic process, triglyceride biosynthetic process endoplasmic reticulum membrane, integral to membrane 2-acylglycerol O-acyltransferase activity, diacylglycerol O-acyltransferase activity Human UniPathway:UPA00282 MOGS Reactome UniProtKB {GO:0009311=GO_REF:0000002, GO:0016020=PMID:7635146, GO:0006457=Reactome:REACT_23878, GO:0005783=PMID:7635146, GO:0004573=GO_REF:0000003, GO:0005789=Reactome:REACT_23855, GO:0015926=PMID:7635146, GO:0006487=PMID:7635146, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q13724 Mannosyl-oligosaccharide glucosidase protein 20130301 {GO:0009311=IEA, GO:0016020=TAS, GO:0006457=TAS, GO:0005783=TAS, GO:0004573=IEA, GO:0005789=TAS, GO:0015926=TAS, GO:0006487=TAS, GO:0016021=IEA, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS} cellular protein metabolic process, oligosaccharide metabolic process, post-translational protein modification, protein N-linked glycosylation, protein N-linked glycosylation via asparagine, protein folding endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, membrane glucosidase activity, mannosyl-oligosaccharide glucosidase activity Human MOK PINC UniProtKB {GO:0007165=PMID:10421840, GO:0005737=GO_REF:0000039, GO:0004672=PMID:10421840, GO:0004674=PMID:10421840, GO:0006468=PMID:10421840, GO:0005524=GO_REF:0000037, GO:0004693=GO_REF:0000003} Q9UQ07 MAPK/MAK/MRK overlapping kinase protein 20030904 {GO:0007165=TAS, GO:0005737=IEA, GO:0004672=TAS, GO:0004674=TAS, GO:0006468=TAS, GO:0005524=IEA, GO:0004693=IEA} protein phosphorylation, signal transduction cytoplasm ATP binding, cyclin-dependent protein serine/threonine kinase activity, protein kinase activity, protein serine/threonine kinase activity Human MON1A ENSEMBL UniProtKB {GO:0006879=GO_REF:0000019, GO:0009306=GO_REF:0000019} Q86VX9 Vacuolar fusion protein MON1 homolog A protein 20130413 {GO:0006879=IEA, GO:0009306=IEA} cellular iron ion homeostasis, protein secretion Human Ensembl:ENSMUSP00000035202 MON1B IntAct UniProtKB {GO:0005515=PMID:20434987} Q7L1V2 Vacuolar fusion protein MON1 homolog B protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:Q9P253 MON2 HGNC UniProtKB {GO:0005802=GO_REF:0000033, GO:0005086=GO_REF:0000033, GO:0030036=GO_REF:0000033, GO:0016192=GO_REF:0000033, GO:0015031=GO_REF:0000037, GO:0006895=GO_REF:0000024} Q7Z3U7 Protein MON2 homolog protein 20070906 {GO:0005802=IBA, GO:0005086=IBA, GO:0030036=IBA, GO:0016192=IBA, GO:0015031=IEA, GO:0006895=ISS} Golgi to endosome transport, actin cytoskeleton organization, protein transport, vesicle-mediated transport trans-Golgi network ARF guanyl-nucleotide exchange factor activity Human UniProtKB:P48563 MORC1 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0007283=GO_REF:0000019, GO:0005524=GO_REF:0000002, GO:0030154=GO_REF:0000037} Q86VD1 MORC family CW-type zinc finger protein 1 protein 20130413 {GO:0005634=IEA, GO:0007275=IEA, GO:0008270=IEA, GO:0007283=IEA, GO:0005524=IEA, GO:0030154=IEA} cell differentiation, multicellular organismal development, spermatogenesis nucleus ATP binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 MORC2 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0005829=GO_REF:0000039} Q9Y6X9 MORC family CW-type zinc finger protein 2 protein 20130413 {GO:0005634=IEA, GO:0008270=IEA, GO:0005524=IEA, GO:0005829=IEA} cytosol, nucleus ATP binding, zinc ion binding Human UniProtKB-SubCell:SL-0091 MORC3 HPA UniProtKB {GO:0016235=GO_REF:0000052, GO:0007569=PMID:17332504, GO:0048147=PMID:17332504, GO:0050821=PMID:17332504, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0009791=GO_REF:0000019, GO:0005524=GO_REF:0000002, GO:0018105=PMID:17332504, GO:0051457=PMID:17332504, GO:0016605=PMID:17332504, GO:0008270=GO_REF:0000002, GO:0006468=PMID:17332504, GO:0045111=GO_REF:0000052} Q14149 MORC family CW-type zinc finger protein 3 protein 20090616 {GO:0016235=IDA, GO:0007569=IDA, GO:0048147=IDA, GO:0050821=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0009791=IEA, GO:0005524=IEA, GO:0018105=IDA, GO:0051457=IDA, GO:0016605=IDA, GO:0008270=IEA, GO:0006468=IDA, GO:0045111=IDA} cell aging, maintenance of protein location in nucleus, negative regulation of fibroblast proliferation, peptidyl-serine phosphorylation, post-embryonic development, protein phosphorylation, protein stabilization PML body, aggresome, intermediate filament cytoskeleton, nucleolus, nucleus ATP binding, zinc ion binding Human MORC4 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0005524=GO_REF:0000002} Q8TE76 MORC family CW-type zinc finger protein 4 protein 20130415 {GO:0005515=IPI, GO:0005634=IEA, GO:0008270=IEA, GO:0005524=IEA} nucleus ATP binding, protein binding, zinc ion binding Human UniProtKB:P40763 MORF4L1 UniProtKB UniProtKB {GO:0005515=PMID:20332121, GO:0016575=PMID:14966270, GO:0006355=GO_REF:0000037, GO:0047485=PMID:17577209, GO:0000724=PMID:20332121, GO:0043967=PMID:14966270, GO:0016580=PMID:14966270, GO:0043968=PMID:14966270, GO:0035267=PMID:14966270, GO:0005634=GO_REF:0000002, GO:0040008=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9UBU8 Mortality factor 4-like protein 1 protein 20101007 {GO:0005515=IPI, GO:0016575=IDA, GO:0006355=IEA, GO:0047485=IPI, GO:0000724=IDA, GO:0043967=IDA, GO:0016580=IDA, GO:0043968=IDA, GO:0035267=IDA, GO:0005634=IEA, GO:0040008=IEA, GO:0006351=IEA} double-strand break repair via homologous recombination, histone H2A acetylation, histone H4 acetylation, histone deacetylation, regulation of growth, regulation of transcription, DNA-dependent, transcription, DNA-dependent NuA4 histone acetyltransferase complex, Sin3 complex, nucleus protein N-terminus binding, protein binding Human UniProtKB:Q86YC2 MORF4L2 ENSEMBL UniProtKB {GO:0005515=PMID:14506250, GO:0006281=GO_REF:0000037, GO:0045944=GO_REF:0000019, GO:0005730=PMID:10942595, GO:0005634=GO_REF:0000002, GO:0051155=GO_REF:0000019, GO:0001558=GO_REF:0000029, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q5JXX6 Mortality factor 4-like protein 2 protein 20130413 {GO:0005515=IPI, GO:0006281=IEA, GO:0045944=IEA, GO:0005730=IDA, GO:0005634=IEA, GO:0051155=IEA, GO:0001558=NAS, GO:0006351=IEA, GO:0016568=IEA} DNA repair, chromatin modification, positive regulation of striated muscle cell differentiation, positive regulation of transcription from RNA polymerase II promoter, regulation of cell growth, transcription, DNA-dependent nucleolus, nucleus protein binding Human Ensembl:ENSRNOP00000003247 MORN1 null null {} null null null null {} null null null MORN2 null null {} null null null null {} null null null MOS ENSEMBL UniProtKB {GO:0040020=GO_REF:0000019, GO:0004674=GO_REF:0000037, GO:0005524=GO_REF:0000037} P00540 Proto-oncogene serine/threonine-protein kinase mos protein 20130413 {GO:0040020=IEA, GO:0004674=IEA, GO:0005524=IEA} regulation of meiosis ATP binding, protein serine/threonine kinase activity Human Ensembl:ENSMUSP00000100789 MOSPD1 BHF-UCL UniProtKB {GO:0048471=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0005198=GO_REF:0000002, GO:0045944=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0000122=GO_REF:0000024, GO:0016021=GO_REF:0000037} Q9UJG1 Motile sperm domain-containing protein 1 protein 20101216 {GO:0048471=ISS, GO:0005737=ISS, GO:0005198=IEA, GO:0045944=ISS, GO:0005634=ISS, GO:0000122=ISS, GO:0016021=IEA} negative regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter cytoplasm, integral to membrane, nucleus, perinuclear region of cytoplasm structural molecule activity Human UniProtKB:Q8VEL0 MOSPD2 UniProtKB UniProtKB {GO:0005198=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q8NHP6 Motile sperm domain-containing protein 2 protein 20130413 {GO:0005198=IEA, GO:0016021=IEA} integral to membrane structural molecule activity Human UniProtKB-KW:KW-0812 MOV10 IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0048011=Reactome:REACT_11061, GO:0006355=GO_REF:0000037, GO:0048015=Reactome:REACT_12464, GO:0003723=GO_REF:0000037, GO:0004386=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0035279=PMID:16289642, GO:0006351=GO_REF:0000037, GO:0005829=Reactome:REACT_147761, GO:0007173=Reactome:REACT_9417, GO:0007219=Reactome:REACT_299, GO:0000932=PMID:16289642, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802} Q9HCE1 Putative helicase MOV-10 protein 20130415 {GO:0005515=IPI, GO:0048011=TAS, GO:0006355=IEA, GO:0048015=TAS, GO:0003723=IEA, GO:0004386=IEA, GO:0005524=IEA, GO:0035279=IDA, GO:0006351=IEA, GO:0005829=TAS, GO:0007173=TAS, GO:0007219=TAS, GO:0000932=IDA, GO:0008543=TAS, GO:0045087=TAS} Notch signaling pathway, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, mRNA cleavage involved in gene silencing by miRNA, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasmic mRNA processing body, cytosol ATP binding, RNA binding, helicase activity, protein binding Human UniProtKB:P19525 MOXD1 UniProtKB UniProtKB {GO:0004500=GO_REF:0000002, GO:0005507=GO_REF:0000002, GO:0006584=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q6UVY6 DBH-like monooxygenase protein 1 protein 20130413 {GO:0004500=IEA, GO:0005507=IEA, GO:0006584=IEA, GO:0005789=IEA, GO:0016021=IEA} catecholamine metabolic process endoplasmic reticulum membrane, integral to membrane copper ion binding, dopamine beta-monooxygenase activity Human UniProtKB-SubCell:SL-0097 MPDU1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0009312=PMID:11733564, GO:0006457=PMID:11179430, GO:0005783=GO_REF:0000052, GO:0005789=PMID:11179430, GO:0006810=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0006488=PMID:11733564} O75352 Mannose-P-dolichol utilization defect 1 protein protein 20101115 {GO:0005739=IDA, GO:0009312=IGI, GO:0006457=NAS, GO:0005783=IDA, GO:0005789=NAS, GO:0006810=IEA, GO:0016021=IEA, GO:0006488=TAS} dolichol-linked oligosaccharide biosynthetic process, oligosaccharide biosynthetic process, protein folding, transport endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, mitochondrion Human MPDZ UniProtKB UniProtKB {GO:0043220=GO_REF:0000019, GO:0005515=PMID:15364909, GO:0042552=GO_REF:0000019, GO:0014069=GO_REF:0000039, GO:0031410=GO_REF:0000019, GO:0008022=PMID:11802782, GO:0016327=PMID:15364909, GO:0016324=GO_REF:0000039, GO:0005737=PMID:15364909, GO:0019048=GO_REF:0000037, GO:0045211=GO_REF:0000037, GO:0005923=GO_REF:0000039, GO:0007155=GO_REF:0000019} O75970 Multiple PDZ domain protein protein 20110926 {GO:0043220=IEA, GO:0005515=IPI, GO:0042552=IEA, GO:0014069=IEA, GO:0031410=IEA, GO:0008022=IPI, GO:0016327=IDA, GO:0016324=IEA, GO:0005737=IDA, GO:0019048=IEA, GO:0045211=IEA, GO:0005923=IEA, GO:0007155=IEA} cell adhesion, myelination, virus-host interaction Schmidt-Lanterman incisure, apical plasma membrane, apicolateral plasma membrane, cytoplasm, cytoplasmic vesicle, postsynaptic density, postsynaptic membrane, tight junction protein C-terminus binding, protein binding Human MPG Reactome UniProtKB {GO:0003905=GO_REF:0000019, GO:0052822=GO_REF:0000003, GO:0052821=GO_REF:0000003, GO:0043916=GO_REF:0000003, GO:0003677=GO_REF:0000002, GO:0008725=GO_REF:0000003, GO:0003684=PMID:10854423, GO:0006307=PMID:1645538, GO:0006281=Reactome:REACT_216, GO:0006284=Reactome:REACT_1104, GO:0045007=Reactome:REACT_2176, GO:0006285=Reactome:REACT_804, GO:0005654=Reactome:REACT_1527} P29372 DNA-3-methyladenine glycosylase protein 20130213 {GO:0003905=IEA, GO:0052822=IEA, GO:0052821=IEA, GO:0043916=IEA, GO:0003677=IEA, GO:0008725=IEA, GO:0003684=TAS, GO:0006307=TAS, GO:0006281=TAS, GO:0006284=TAS, GO:0045007=TAS, GO:0006285=TAS, GO:0005654=TAS} DNA dealkylation involved in DNA repair, DNA repair, base-excision repair, base-excision repair, AP site formation, depurination nucleoplasm DNA binding, DNA-3-methyladenine glycosylase activity, DNA-3-methylguanine glycosylase activity, DNA-7-methyladenine glycosylase activity, DNA-7-methylguanine glycosylase activity, alkylbase DNA N-glycosylase activity, damaged DNA binding Human MPHOSPH10 HPA UniProtKB {GO:0005515=PMID:12655004, GO:0008380=PMID:9450966, GO:0006396=PMID:9450966, GO:0005694=GO_REF:0000039, GO:0010923=PMID:19389623, GO:0000375=PMID:9450966, GO:0030529=GO_REF:0000002, GO:0006364=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005732=PMID:9450966} O00566 U3 small nucleolar ribonucleoprotein protein MPP10 protein 20101115 {GO:0005515=IPI, GO:0008380=NAS, GO:0006396=NAS, GO:0005694=IEA, GO:0010923=IDA, GO:0000375=NAS, GO:0030529=IEA, GO:0006364=IEA, GO:0005730=IDA, GO:0005732=NAS} RNA processing, RNA splicing, RNA splicing, via transesterification reactions, negative regulation of phosphatase activity, rRNA processing chromosome, nucleolus, ribonucleoprotein complex, small nucleolar ribonucleoprotein complex protein binding Human MPHOSPH6 HPA UniProtKB {GO:0005515=PMID:17412707, GO:0005737=GO_REF:0000052, GO:0000460=PMID:17412707, GO:0003723=GO_REF:0000037, GO:0000087=PMID:8885239, GO:0000176=PMID:11719186, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000178=PMID:20531389} Q99547 M-phase phosphoprotein 6 protein 20111111 {GO:0005515=IPI, GO:0005737=IDA, GO:0000460=IMP, GO:0003723=IEA, GO:0000087=TAS, GO:0000176=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0000178=IDA} M phase of mitotic cell cycle, maturation of 5.8S rRNA cytoplasm, exosome (RNase complex), nuclear exosome (RNase complex), nucleolus, nucleus RNA binding, protein binding Human MPHOSPH8 HPA UniProtKB {GO:0005720=PMID:20871592, GO:0005737=GO_REF:0000052, GO:0007049=PMID:8885239, GO:0005886=GO_REF:0000052, GO:0044030=PMID:20871592, GO:0005730=GO_REF:0000052, GO:0000788=PMID:20871592, GO:0005634=GO_REF:0000052, GO:0035064=PMID:20871592, GO:0045892=PMID:20871592, GO:0006351=GO_REF:0000037} Q99549 M-phase phosphoprotein 8 protein 20110516 {GO:0005720=IDA, GO:0005737=IDA, GO:0007049=NAS, GO:0005886=IDA, GO:0044030=IMP, GO:0005730=IDA, GO:0000788=IDA, GO:0005634=IDA, GO:0035064=IDA, GO:0045892=IMP, GO:0006351=IEA} cell cycle, negative regulation of transcription, DNA-dependent, regulation of DNA methylation, transcription, DNA-dependent cytoplasm, nuclear heterochromatin, nuclear nucleosome, nucleolus, nucleus, plasma membrane methylated histone residue binding Human MPHOSPH9 HPA UniProtKB {GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0005794=PMID:8885239, GO:0000139=GO_REF:0000039, GO:0005886=GO_REF:0000052, GO:0005814=GO_REF:0000039, GO:0000087=PMID:8885239, GO:0005634=GO_REF:0000052} Q99550 M-phase phosphoprotein 9 protein 20111111 {GO:0005813=IDA, GO:0005737=IDA, GO:0005794=TAS, GO:0000139=IEA, GO:0005886=IDA, GO:0005814=IEA, GO:0000087=TAS, GO:0005634=IDA} M phase of mitotic cell cycle Golgi apparatus, Golgi membrane, centriole, centrosome, cytoplasm, nucleus, plasma membrane Human MPI HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005975=GO_REF:0000002, GO:0009298=Reactome:REACT_22423, GO:0008270=GO_REF:0000002, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426, GO:0005829=Reactome:REACT_22388, GO:0004476=GO_REF:0000003} P34949 Mannose-6-phosphate isomerase protein 20081203 {GO:0005737=IDA, GO:0005975=IEA, GO:0009298=TAS, GO:0008270=IEA, GO:0006488=TAS, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS, GO:0005829=TAS, GO:0004476=IEA} GDP-mannose biosynthetic process, carbohydrate metabolic process, cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine cytoplasm, cytosol mannose-6-phosphate isomerase activity, zinc ion binding Human MPL InterPro UniProtKB {GO:0048872=GO_REF:0000019, GO:0004896=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0007596=Reactome:REACT_604, GO:0008283=PMID:8020956, GO:0005887=PMID:8020956, GO:0032642=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0007166=PMID:8020956, GO:0004888=PMID:8020956} Q5JUY5 Myeloproliferative leukemia virus oncogene, isoform CRA_c protein 20130413 {GO:0048872=IEA, GO:0004896=IEA, GO:0016020=IEA, GO:0005886=IDA, GO:0007596=TAS, GO:0008283=TAS, GO:0005887=TAS, GO:0032642=IEA, GO:0030168=TAS, GO:0007166=TAS, GO:0004888=TAS} blood coagulation, cell proliferation, cell surface receptor signaling pathway, homeostasis of number of cells, platelet activation, regulation of chemokine production integral to plasma membrane, membrane, plasma membrane cytokine receptor activity, transmembrane signaling receptor activity Human InterPro:IPR003528 MPND UniProtKB UniProtKB {GO:0006508=GO_REF:0000037, GO:0008233=GO_REF:0000037} Q8N594 MPN domain-containing protein protein 20130413 {GO:0006508=IEA, GO:0008233=IEA} proteolysis peptidase activity Human UniProtKB-KW:KW-0645 MPO BHF-UCL UniProtKB {GO:0043066=PMID:10801811, GO:0050832=GO_REF:0000019, GO:0005634=PMID:2829220, GO:0006952=PMID:8621627, GO:0005615=PMID:10772654, GO:0001878=GO_REF:0000019, GO:0005764=GO_REF:0000039, GO:0046872=GO_REF:0000037, GO:0002679=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0004601=PMID:10772654, GO:0034374=PMID:10772654, GO:0019430=GO_REF:0000019, GO:0003682=PMID:2829220, GO:0042744=PMID:10772654, GO:0030141=PMID:11907569, GO:0044130=GO_REF:0000019, GO:0008201=PMID:11907569, GO:0006979=PMID:2903767, GO:0055114=PMID:10772654, GO:0020037=GO_REF:0000002, GO:0002149=GO_REF:0000019} P05164 Myeloperoxidase protein 20090114 {GO:0043066=TAS, GO:0050832=IEA, GO:0005634=TAS, GO:0006952=TAS, GO:0005615=IDA, GO:0001878=IEA, GO:0005764=IEA, GO:0046872=IEA, GO:0002679=IEA, GO:0005739=IEA, GO:0004601=IDA, GO:0034374=IDA, GO:0019430=IEA, GO:0003682=TAS, GO:0042744=IDA, GO:0030141=IDA, GO:0044130=IEA, GO:0008201=IDA, GO:0006979=TAS, GO:0055114=IDA, GO:0020037=IEA, GO:0002149=IEA} defense response, defense response to fungus, hydrogen peroxide catabolic process, hypochlorous acid biosynthetic process, low-density lipoprotein particle remodeling, negative regulation of apoptotic process, negative regulation of growth of symbiont in host, oxidation-reduction process, removal of superoxide radicals, respiratory burst involved in defense response, response to oxidative stress, response to yeast extracellular space, lysosome, mitochondrion, nucleus, secretory granule chromatin binding, heme binding, heparin binding, metal ion binding, peroxidase activity Human MPP1 IntAct UniProtKB {GO:0005622=GO_REF:0000054, GO:0005515=PMID:21903422, GO:0007165=PMID:1713685, GO:0016020=PMID:1713685, GO:0005887=PMID:1713685, GO:0090022=GO_REF:0000024, GO:0004385=PMID:1310897, GO:0032420=GO_REF:0000039, GO:0030863=GO_REF:0000019} Q00013 55 kDa erythrocyte membrane protein protein 20130415 {GO:0005622=IDA, GO:0005515=IPI, GO:0007165=TAS, GO:0016020=TAS, GO:0005887=TAS, GO:0090022=ISS, GO:0004385=TAS, GO:0032420=IEA, GO:0030863=IEA} regulation of neutrophil chemotaxis, signal transduction cortical cytoskeleton, integral to plasma membrane, intracellular, membrane, stereocilium guanylate kinase activity, protein binding Human UniProtKB:Q96CV9 MPP2 PINC UniProtKB {GO:0007165=PMID:7590743, GO:0016020=PMID:7590743, GO:0009986=PMID:12493773, GO:0005887=PMID:7590743, GO:0004385=PMID:7590743} Q14168 MAGUK p55 subfamily member 2 protein 20030904 {GO:0007165=TAS, GO:0016020=TAS, GO:0009986=IDA, GO:0005887=TAS, GO:0004385=TAS} signal transduction cell surface, integral to plasma membrane, membrane guanylate kinase activity Human MPP3 PINC UniProtKB {GO:0007165=PMID:8824795, GO:0009986=PMID:12493773, GO:0005887=PMID:8824795, GO:0004385=PMID:8824795, GO:0030165=GO_REF:0000019} Q13368 MAGUK p55 subfamily member 3 protein 20030904 {GO:0007165=TAS, GO:0009986=IDA, GO:0005887=TAS, GO:0004385=TAS, GO:0030165=IEA} signal transduction cell surface, integral to plasma membrane PDZ domain binding, guanylate kinase activity Human MPP4 UniProtKB UniProtKB {GO:0042734=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0035418=GO_REF:0000019} Q96JB8 MAGUK p55 subfamily member 4 protein 20130413 {GO:0042734=IEA, GO:0005737=IEA, GO:0035418=IEA} protein localization to synapse cytoplasm, presynaptic membrane Human UniProtKB-SubCell:SL-0086 MPP5 BHF-UCL UniProtKB {GO:0043220=GO_REF:0000019, GO:0005515=PMID:17584769, GO:0005886=Reactome:REACT_19144, GO:0034329=Reactome:REACT_20676, GO:0019904=PMID:17332497, GO:0035750=GO_REF:0000019, GO:0045216=Reactome:REACT_19331, GO:0032287=GO_REF:0000019, GO:0032288=GO_REF:0000019, GO:0012505=GO_REF:0000039, GO:0035749=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0005737=GO_REF:0000054, GO:0070830=Reactome:REACT_19373, GO:0043219=GO_REF:0000019, GO:0005923=GO_REF:0000039, GO:0090002=GO_REF:0000019} Q8N3R9 MAGUK p55 subfamily member 5 protein 20110307 {GO:0043220=IEA, GO:0005515=IPI, GO:0005886=TAS, GO:0034329=TAS, GO:0019904=IPI, GO:0035750=IEA, GO:0045216=TAS, GO:0032287=IEA, GO:0032288=IEA, GO:0012505=IEA, GO:0035749=IEA, GO:0043234=IEA, GO:0005737=IDA, GO:0070830=TAS, GO:0043219=IEA, GO:0005923=IEA, GO:0090002=IEA} cell junction assembly, cell-cell junction organization, establishment of protein localization to plasma membrane, myelin assembly, peripheral nervous system myelin maintenance, protein localization to myelin sheath abaxonal region, tight junction assembly Schmidt-Lanterman incisure, cytoplasm, endomembrane system, lateral loop, myelin sheath adaxonal region, plasma membrane, protein complex, tight junction protein binding, protein domain specific binding Human UniProtKB:Q9BUF7 MPP6 UniProtKB UniProtKB {GO:0005515=PMID:11311936, GO:0006461=PMID:11311936, GO:0016020=PMID:11311936, GO:0005886=GO_REF:0000019} Q9NZW5 MAGUK p55 subfamily member 6 protein 20030408 {GO:0005515=IPI, GO:0006461=NAS, GO:0016020=NAS, GO:0005886=IEA} protein complex assembly membrane, plasma membrane protein binding Human MPP7 GOC UniProtKB {GO:0005515=PMID:17237226, GO:0035591=PMID:14719143, GO:0046982=PMID:17237226, GO:0019904=PMID:17332497, GO:0097025=PMID:17237226, GO:0030010=PMID:17332497, GO:0009967=PMID:20702775, GO:0032947=PMID:17237226, GO:0031334=PMID:17237226, GO:0005912=PMID:17237226, GO:0070830=PMID:17332497, GO:0071896=PMID:17237226, GO:0005923=PMID:17332497} Q5T2T1 MAGUK p55 subfamily member 7 protein 20130413 {GO:0005515=IPI, GO:0035591=NAS, GO:0046982=IDA, GO:0019904=IPI, GO:0097025=IDA, GO:0030010=TAS, GO:0009967=TAS, GO:0032947=IDA, GO:0031334=IDA, GO:0005912=IDA, GO:0070830=IDA, GO:0071896=IMP, GO:0005923=IDA} establishment of cell polarity, positive regulation of protein complex assembly, positive regulation of signal transduction, protein localization to adherens junction, tight junction assembly MPP7-DLG1-LIN7 complex, adherens junction, tight junction protein binding, protein complex scaffold, protein domain specific binding, protein heterodimerization activity, signaling adaptor activity Human MPPE1 UniProtKB UniProtKB {GO:0006888=GO_REF:0000024, GO:0005801=GO_REF:0000024, GO:0008081=GO_REF:0000024, GO:0005793=GO_REF:0000024, GO:0030145=GO_REF:0000024, GO:0034235=GO_REF:0000024, GO:0005794=GO_REF:0000039, GO:0016787=GO_REF:0000002, GO:0033116=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0070971=GO_REF:0000024, GO:0006506=GO_REF:0000024} Q53F39 Metallophosphoesterase 1 protein 20100423 {GO:0006888=ISS, GO:0005801=ISS, GO:0008081=ISS, GO:0005793=ISS, GO:0030145=ISS, GO:0034235=ISS, GO:0005794=IEA, GO:0016787=IEA, GO:0033116=IEA, GO:0016021=IEA, GO:0070971=ISS, GO:0006506=ISS} ER to Golgi vesicle-mediated transport, GPI anchor biosynthetic process Golgi apparatus, cis-Golgi network, endoplasmic reticulum exit site, endoplasmic reticulum-Golgi intermediate compartment, endoplasmic reticulum-Golgi intermediate compartment membrane, integral to membrane GPI anchor binding, hydrolase activity, manganese ion binding, phosphoric diester hydrolase activity Human UniProtKB:C7G3A0 MPPED1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0016787=GO_REF:0000037, GO:0005575=GO_REF:0000015} O15442 Metallophosphoesterase domain-containing protein 1 protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0016787=IEA, GO:0005575=ND} biological_process cellular_component hydrolase activity, molecular_function Human MPPED2 PINC UniProtKB {GO:0016787=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0007399=PMID:7527372} Q15777 Metallophosphoesterase MPPED2 protein 20030904 {GO:0016787=IEA, GO:0046872=IEA, GO:0007399=TAS} nervous system development hydrolase activity, metal ion binding Human MPRIP UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0005543=GO_REF:0000002, GO:0003779=GO_REF:0000037, GO:0005856=GO_REF:0000039} Q6WCQ1 Myosin phosphatase Rho-interacting protein protein 20130413 {GO:0005737=IEA, GO:0005543=IEA, GO:0003779=IEA, GO:0005856=IEA} cytoplasm, cytoskeleton actin binding, phospholipid binding Human UniProtKB-SubCell:SL-0090 MPST HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0043005=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0070814=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0009440=PMID:9070219, GO:0016784=GO_REF:0000003, GO:0005743=GO_REF:0000019, GO:0009636=PMID:9070219, GO:0045202=GO_REF:0000037, GO:0004792=GO_REF:0000002} P25325 3-mercaptopyruvate sulfurtransferase protein 20101115 {GO:0005739=IDA, GO:0043005=ISS, GO:0005737=IDA, GO:0070814=ISS, GO:0030054=IEA, GO:0009440=TAS, GO:0016784=IEA, GO:0005743=IEA, GO:0009636=TAS, GO:0045202=IEA, GO:0004792=IEA} cyanate catabolic process, hydrogen sulfide biosynthetic process, response to toxic substance cell junction, cytoplasm, mitochondrial inner membrane, mitochondrion, neuron projection, synapse 3-mercaptopyruvate sulfurtransferase activity, thiosulfate sulfurtransferase activity Human MPV17 MGI UniProtKB {GO:0005739=PMID:16582910, GO:0003674=GO_REF:0000015, GO:0048839=GO_REF:0000024, GO:0072593=GO_REF:0000019, GO:0005743=PMID:16582910, GO:0034614=GO_REF:0000024, GO:0042592=PMID:16582910, GO:2000377=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0032836=GO_REF:0000024, GO:0000002=PMID:16582910, GO:0005777=PMID:16582910} P39210 Protein Mpv17 protein 20060728 {GO:0005739=IDA, GO:0003674=ND, GO:0048839=ISS, GO:0072593=IEA, GO:0005743=IDA, GO:0034614=ISS, GO:0042592=IMP, GO:2000377=ISS, GO:0016021=IEA, GO:0032836=ISS, GO:0000002=IMP, GO:0005777=IDA} cellular response to reactive oxygen species, glomerular basement membrane development, homeostatic process, inner ear development, mitochondrial genome maintenance, reactive oxygen species metabolic process, regulation of reactive oxygen species metabolic process integral to membrane, mitochondrial inner membrane, mitochondrion, peroxisome molecular_function Human MPV17L BHF-UCL UniProtKB {GO:0003674=GO_REF:0000015, GO:0010730=PMID:22306510, GO:0005102=PMID:20178365, GO:1901029=PMID:22306510, GO:0016021=GO_REF:0000037, GO:0005778=GO_REF:0000039} Q2QL34 Mpv17-like protein protein 20121109 {GO:0003674=ND, GO:0010730=IDA, GO:0005102=IPI, GO:1901029=IDA, GO:0016021=IEA, GO:0005778=IEA} negative regulation of hydrogen peroxide biosynthetic process, negative regulation of mitochondrial outer membrane permeabilization integral to membrane, peroxisomal membrane molecular_function, receptor binding Human MPV17L2 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q567V2 Mpv17-like protein 2 protein 20130413 {GO:0005739=IEA, GO:0016021=IEA} integral to membrane, mitochondrion Human Ensembl:ENSMUSP00000037929 MPZ PINC UniProtKB {GO:0005886=PMID:7693130, GO:0005887=PMID:7506095, GO:0005198=PMID:7693129, GO:0043209=GO_REF:0000039, GO:0007268=PMID:7693129, GO:0016021=GO_REF:0000038, GO:0045217=GO_REF:0000019} P25189 Myelin protein P0 protein 20030904 {GO:0005886=NAS, GO:0005887=TAS, GO:0005198=NAS, GO:0043209=IEA, GO:0007268=TAS, GO:0016021=IEA, GO:0045217=IEA} cell-cell junction maintenance, synaptic transmission integral to membrane, integral to plasma membrane, myelin sheath, plasma membrane structural molecule activity Human MPZL1 UniProtKB UniProtKB {GO:0005515=PMID:9792637, GO:0016020=GO_REF:0000038, GO:0005887=PMID:9792637, GO:0005198=PMID:9792637, GO:0007267=PMID:9792637, GO:0007169=PMID:10681522} Q9UEL6 Myelin protein zero-like protein 1 protein 20130413 {GO:0005515=IPI, GO:0016020=IEA, GO:0005887=TAS, GO:0005198=TAS, GO:0007267=TAS, GO:0007169=TAS} cell-cell signaling, transmembrane receptor protein tyrosine kinase signaling pathway integral to plasma membrane, membrane protein binding, structural molecule activity Human UniProtKB-KW:KW-0472 MPZL2 IntAct UniProtKB {GO:0005515=PMID:21982860, GO:0033077=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0005856=PMID:9585423, GO:0009653=PMID:9585423, GO:0007156=PMID:9585423} O60487 Myelin protein zero-like protein 2 protein 20130415 {GO:0005515=IPI, GO:0033077=IEA, GO:0005886=IEA, GO:0016021=IEA, GO:0005856=TAS, GO:0009653=TAS, GO:0007156=TAS} T cell differentiation in thymus, anatomical structure morphogenesis, homophilic cell adhesion cytoskeleton, integral to membrane, plasma membrane protein binding Human UniProtKB:Q6UWV2 MR1 MGI UniProtKB {GO:0002474=GO_REF:0000037, GO:0006955=GO_REF:0000002, GO:0005783=PMID:21190736, GO:0042612=GO_REF:0000037, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0032393=PMID:7624800} Q95460 Major histocompatibility complex class I-related gene protein protein 20130220 {GO:0002474=IEA, GO:0006955=IEA, GO:0005783=IDA, GO:0042612=IEA, GO:0005576=IEA, GO:0016021=IEA, GO:0032393=TAS} antigen processing and presentation of peptide antigen via MHC class I, immune response MHC class I protein complex, endoplasmic reticulum, extracellular region, integral to membrane MHC class I receptor activity Human MRAP BHF-UCL UniProtKB {GO:0070996=PMID:19329486, GO:0048471=GO_REF:0000039, GO:0031783=PMID:19329486, GO:0005886=PMID:19329486, GO:0005783=PMID:19329486, GO:0050873=GO_REF:0000019, GO:0031781=PMID:19329486, GO:0034394=PMID:19329486, GO:0031782=PMID:19329486, GO:0030819=PMID:19329486, GO:0016021=GO_REF:0000037, GO:0031780=PMID:19329486} Q8TCY5 Melanocortin-2 receptor accessory protein protein 20100130 {GO:0070996=IPI, GO:0048471=IEA, GO:0031783=IPI, GO:0005886=IDA, GO:0005783=IDA, GO:0050873=IEA, GO:0031781=IPI, GO:0034394=IDA, GO:0031782=IPI, GO:0030819=IDA, GO:0016021=IEA, GO:0031780=IPI} brown fat cell differentiation, positive regulation of cAMP biosynthetic process, protein localization to cell surface endoplasmic reticulum, integral to membrane, perinuclear region of cytoplasm, plasma membrane corticotropin hormone receptor binding, type 1 melanocortin receptor binding, type 3 melanocortin receptor binding, type 4 melanocortin receptor binding, type 5 melanocortin receptor binding Human UniProtKB:Q01718 MRAP2 BHF-UCL UniProtKB {GO:0070996=PMID:19329486, GO:0031783=PMID:19329486, GO:0005886=PMID:19329486, GO:0005783=PMID:19329486, GO:0031781=PMID:19329486, GO:0034394=PMID:19329486, GO:0031782=PMID:19329486, GO:0030819=PMID:19329486, GO:0031780=PMID:19329486} Q96G30 Melanocortin-2 receptor accessory protein 2 protein 20100130 {GO:0070996=IPI, GO:0031783=IPI, GO:0005886=IDA, GO:0005783=IDA, GO:0031781=IPI, GO:0034394=IDA, GO:0031782=IPI, GO:0030819=IDA, GO:0031780=IPI} positive regulation of cAMP biosynthetic process, protein localization to cell surface endoplasmic reticulum, plasma membrane corticotropin hormone receptor binding, type 1 melanocortin receptor binding, type 3 melanocortin receptor binding, type 4 melanocortin receptor binding, type 5 melanocortin receptor binding Human UniProtKB:P33032 MRAS PINC UniProtKB {GO:0030742=PMID:10934204, GO:0007517=PMID:9395237, GO:0030036=PMID:9395237, GO:0005886=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0003924=GO_REF:0000002, GO:0007275=PMID:10446149, GO:0007265=PMID:10446149, GO:0005525=GO_REF:0000037} O14807 Ras-related protein M-Ras protein 20030904 {GO:0030742=IPI, GO:0007517=TAS, GO:0030036=TAS, GO:0005886=IEA, GO:0016020=IEA, GO:0007264=IEA, GO:0003924=IEA, GO:0007275=TAS, GO:0007265=TAS, GO:0005525=IEA} Ras protein signal transduction, actin cytoskeleton organization, multicellular organismal development, muscle organ development, small GTPase mediated signal transduction membrane, plasma membrane GTP binding, GTP-dependent protein binding, GTPase activity Human MRC1 PINC UniProtKB {GO:0005886=PMID:20035344, GO:0005887=PMID:1294118, GO:0004872=PMID:20035344, GO:0005537=PMID:2373685, GO:0010008=PMID:20035344, GO:0006898=PMID:20035344} P22897 Macrophage mannose receptor 1 protein 20030904 {GO:0005886=IDA, GO:0005887=TAS, GO:0004872=IDA, GO:0005537=TAS, GO:0010008=IDA, GO:0006898=IDA} receptor-mediated endocytosis endosome membrane, integral to plasma membrane, plasma membrane mannose binding, receptor activity Human MRC2 UniProtKB UniProtKB {GO:0030246=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0006897=GO_REF:0000037} Q9UBG0 C-type mannose receptor 2 protein 20130413 {GO:0030246=IEA, GO:0016021=IEA, GO:0006897=IEA} endocytosis integral to membrane carbohydrate binding Human UniProtKB-KW:KW-0812 MRE11A GOC UniProtKB {GO:0005515=PMID:17612497, GO:0008408=PMID:9651580, GO:0030870=PMID:15790808, GO:0090305=PMID:15790808, GO:0008283=GO_REF:0000019, GO:0032876=PMID:15917200, GO:0005634=GO_REF:0000052, GO:0006303=PMID:9651580, GO:0006302=Reactome:REACT_2054, GO:0004527=GO_REF:0000038, GO:0004003=PMID:15790808, GO:0003690=PMID:10802669, GO:0000724=Reactome:REACT_1874, GO:0032508=PMID:15790808, GO:0031954=PMID:15790808, GO:0007131=PMID:8530104, GO:0033674=PMID:15790808, GO:0000781=PMID:15149599, GO:0030145=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0004520=PMID:9651580, GO:0006310=PMID:9705271, GO:0006259=GO_REF:0000002, GO:0008022=PMID:9590181, GO:0003677=PMID:15790808, GO:0006974=PMID:17500065, GO:0007129=GO_REF:0000019, GO:0004518=PMID:15790808, GO:0007126=GO_REF:0000038, GO:0004519=GO_REF:0000038, GO:0006281=Reactome:REACT_216, GO:0000014=PMID:9705271, GO:0007062=PMID:15917200, GO:0000075=GO_REF:0000019, GO:0005654=Reactome:REACT_1232, GO:0007004=PMID:9705271, GO:0000019=PMID:8530104} P49959 Double-strand break repair protein MRE11A protein 20130413 {GO:0005515=IPI, GO:0008408=TAS, GO:0030870=NAS, GO:0090305=TAS, GO:0008283=IEA, GO:0032876=IMP, GO:0005634=IDA, GO:0006303=TAS, GO:0006302=TAS, GO:0004527=IEA, GO:0004003=IMP, GO:0003690=TAS, GO:0000724=TAS, GO:0032508=IMP, GO:0031954=IDA, GO:0007131=TAS, GO:0033674=IDA, GO:0000781=IDA, GO:0030145=IEA, GO:0005730=IDA, GO:0004520=TAS, GO:0006310=TAS, GO:0006259=IEA, GO:0008022=IPI, GO:0003677=IDA, GO:0006974=IDA, GO:0007129=IEA, GO:0004518=TAS, GO:0007126=IEA, GO:0004519=IEA, GO:0006281=TAS, GO:0000014=TAS, GO:0007062=IMP, GO:0000075=IEA, GO:0005654=TAS, GO:0007004=TAS, GO:0000019=TAS} DNA duplex unwinding, DNA metabolic process, DNA recombination, DNA repair, cell cycle checkpoint, cell proliferation, double-strand break repair, double-strand break repair via homologous recombination, double-strand break repair via nonhomologous end joining, meiosis, negative regulation of DNA endoreduplication, nucleic acid phosphodiester bond hydrolysis, positive regulation of kinase activity, positive regulation of protein autophosphorylation, reciprocal meiotic recombination, regulation of mitotic recombination, response to DNA damage stimulus, sister chromatid cohesion, synapsis, telomere maintenance via telomerase Mre11 complex, chromosome, telomeric region, nucleolus, nucleoplasm, nucleus 3'-5' exonuclease activity, ATP-dependent DNA helicase activity, DNA binding, double-stranded DNA binding, endodeoxyribonuclease activity, endonuclease activity, exonuclease activity, manganese ion binding, nuclease activity, protein C-terminus binding, protein binding, single-stranded DNA specific endodeoxyribonuclease activity Human MREG UniProtKB UniProtKB {GO:0016324=GO_REF:0000039, GO:0042640=GO_REF:0000019, GO:0030318=GO_REF:0000019} Q8N565 Melanoregulin protein 20130413 {GO:0016324=IEA, GO:0042640=IEA, GO:0030318=IEA} anagen, melanocyte differentiation apical plasma membrane Human UniProtKB-SubCell:SL-0015 MRFAP1 UniProtKB UniProtKB {GO:0005515=PMID:11500496, GO:0048471=GO_REF:0000039, GO:0005634=GO_REF:0000039} Q9Y605 MORF4 family-associated protein 1 protein 20070927 {GO:0005515=IPI, GO:0048471=IEA, GO:0005634=IEA} nucleus, perinuclear region of cytoplasm protein binding Human UniProtKB:Q9UBU8 MRFAP1L1 IntAct UniProtKB {GO:0005515=PMID:23275563} Q96HT8 MORF4 family-associated protein 1-like 1 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:P42858 MRGPRX1 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0006953=GO_REF:0000037} Q96LB2 Mas-related G-protein coupled receptor member X1 protein 20130413 {GO:0005886=IEA, GO:0004930=IEA, GO:0016021=IEA, GO:0006953=IEA} acute-phase response integral to membrane, plasma membrane G-protein coupled receptor activity Human UniProtKB-SubCell:SL-0039 MRGPRX2 UniProtKB UniProtKB {GO:0042923=PMID:12915402, GO:0005886=GO_REF:0000039, GO:0004930=PMID:12915402, GO:0030431=PMID:12915402, GO:0016021=PMID:12915402, GO:0019233=PMID:12915402} Q96LB1 Mas-related G-protein coupled receptor member X2 protein 20040928 {GO:0042923=IPI, GO:0005886=IEA, GO:0004930=IDA, GO:0030431=NAS, GO:0016021=IC, GO:0019233=NAS} sensory perception of pain, sleep integral to membrane, plasma membrane G-protein coupled receptor activity, neuropeptide binding Human MRI1 IntAct UniProtKB {GO:0019284=GO_REF:0000020, GO:0005634=GO_REF:0000039, GO:0042995=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_75853, GO:0042802=PMID:19447967, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000033, GO:0000096=Reactome:REACT_115639, GO:0019509=Reactome:REACT_75881, GO:0006595=Reactome:REACT_14820, GO:0044249=GO_REF:0000002, GO:0046523=GO_REF:0000033} Q9BV20 Methylthioribose-1-phosphate isomerase protein 20130415 {GO:0019284=IEA, GO:0005634=IEA, GO:0042995=IEA, GO:0044281=TAS, GO:0005829=TAS, GO:0042802=IPI, GO:0034641=TAS, GO:0005737=IBA, GO:0000096=TAS, GO:0019509=TAS, GO:0006595=TAS, GO:0044249=IEA, GO:0046523=IBA} L-methionine biosynthetic process from S-adenosylmethionine, L-methionine salvage from methylthioadenosine, cellular biosynthetic process, cellular nitrogen compound metabolic process, polyamine metabolic process, small molecule metabolic process, sulfur amino acid metabolic process cell projection, cytoplasm, cytosol, nucleus S-methyl-5-thioribose-1-phosphate isomerase activity, identical protein binding Human UniProtKB:Q9BV20 MRM1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0006396=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0008173=GO_REF:0000002} Q6IN84 rRNA methyltransferase 1, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0006396=IEA, GO:0003723=IEA, GO:0008173=IEA} RNA processing mitochondrion RNA binding, RNA methyltransferase activity Human UniProtKB-SubCell:SL-0173 MRP63 ENSEMBL UniProtKB {GO:0003735=GO_REF:0000019, GO:0005761=GO_REF:0000019, GO:0006412=GO_REF:0000019} Q9BQC6 Ribosomal protein 63, mitochondrial protein 20130413 {GO:0003735=IEA, GO:0005761=IEA, GO:0006412=IEA} translation mitochondrial ribosome structural constituent of ribosome Human Ensembl:ENSMUSP00000022538 MRPL1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0003735=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0015934=GO_REF:0000002, GO:0006412=GO_REF:0000002} Q9BYD6 39S ribosomal protein L1, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0003735=IEA, GO:0003723=IEA, GO:0015934=IEA, GO:0006412=IEA} translation large ribosomal subunit, mitochondrion RNA binding, structural constituent of ribosome Human UniProtKB-SubCell:SL-0173 MRPL10 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0003735=GO_REF:0000024, GO:0030529=GO_REF:0000024, GO:0042254=GO_REF:0000002, GO:0006412=GO_REF:0000024, GO:0005762=GO_REF:0000024} Q7Z7H8 39S ribosomal protein L10, mitochondrial protein 20090616 {GO:0005739=IDA, GO:0003735=ISS, GO:0030529=ISS, GO:0042254=IEA, GO:0006412=ISS, GO:0005762=ISS} ribosome biogenesis, translation mitochondrial large ribosomal subunit, mitochondrion, ribonucleoprotein complex structural constituent of ribosome Human MRPL11 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0003735=PMID:11543634, GO:0005761=PMID:11543634, GO:0005840=GO_REF:0000002, GO:0006412=PMID:11543634} Q9Y3B7 39S ribosomal protein L11, mitochondrial protein 20130415 {GO:0005515=IPI, GO:0003735=NAS, GO:0005761=NAS, GO:0005840=IEA, GO:0006412=NAS} translation mitochondrial ribosome, ribosome protein binding, structural constituent of ribosome Human UniProtKB:P04591:PRO_0000038596 MRPL12 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005515=PMID:17337445, GO:0003735=GO_REF:0000002, GO:0003723=PMID:8626705, GO:0006390=PMID:17337445, GO:0045893=PMID:17337445, GO:0006412=GO_REF:0000002, GO:0005762=PMID:20186120} P52815 39S ribosomal protein L12, mitochondrial protein 20100326 {GO:0005739=IDA, GO:0005515=IPI, GO:0003735=IEA, GO:0003723=TAS, GO:0006390=IDA, GO:0045893=IDA, GO:0006412=IEA, GO:0005762=IDA} positive regulation of transcription, DNA-dependent, transcription from mitochondrial promoter, translation mitochondrial large ribosomal subunit, mitochondrion RNA binding, protein binding, structural constituent of ribosome Human MRPL13 MGI UniProtKB {GO:0005515=PMID:20601428, GO:0005739=GO_REF:0000019, GO:0003735=PMID:11279069, GO:0005761=PMID:20601428, GO:0005840=GO_REF:0000002, GO:0006412=PMID:11279069, GO:0005762=PMID:21531335} Q9BYD1 39S ribosomal protein L13, mitochondrial protein 20111227 {GO:0005515=IPI, GO:0005739=IEA, GO:0003735=NAS, GO:0005761=IDA, GO:0005840=IEA, GO:0006412=NAS, GO:0005762=IDA} translation mitochondrial large ribosomal subunit, mitochondrial ribosome, mitochondrion, ribosome protein binding, structural constituent of ribosome Human MRPL14 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0003735=GO_REF:0000002, GO:0005840=GO_REF:0000037, GO:0006412=GO_REF:0000002} Q6P1L8 39S ribosomal protein L14, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0003735=IEA, GO:0005840=IEA, GO:0006412=IEA} translation mitochondrion, ribosome structural constituent of ribosome Human UniProtKB-SubCell:SL-0173 MRPL15 LIFEdb UniProtKB {GO:0005739=GO_REF:0000054, GO:0003735=GO_REF:0000002, GO:0015934=GO_REF:0000002, GO:0006412=GO_REF:0000002} Q9P015 39S ribosomal protein L15, mitochondrial protein 20100607 {GO:0005739=IDA, GO:0003735=IEA, GO:0015934=IEA, GO:0006412=IEA} translation large ribosomal subunit, mitochondrion structural constituent of ribosome Human MRPL16 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0003735=GO_REF:0000002, GO:0005840=GO_REF:0000037, GO:0019843=GO_REF:0000002, GO:0006412=GO_REF:0000002} Q9NX20 39S ribosomal protein L16, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0003735=IEA, GO:0005840=IEA, GO:0019843=IEA, GO:0006412=IEA} translation mitochondrion, ribosome rRNA binding, structural constituent of ribosome Human UniProtKB-SubCell:SL-0173 MRPL17 UniProtKB UniProtKB {GO:0003735=GO_REF:0000002, GO:0019904=PMID:11984006, GO:0005743=GO_REF:0000019, GO:0005840=GO_REF:0000037, GO:0006412=GO_REF:0000002} Q9NRX2 39S ribosomal protein L17, mitochondrial protein 20080612 {GO:0003735=IEA, GO:0019904=IPI, GO:0005743=IEA, GO:0005840=IEA, GO:0006412=IEA} translation mitochondrial inner membrane, ribosome protein domain specific binding, structural constituent of ribosome Human UniProtKB:Q99698 MRPL18 LIFEdb UniProtKB {GO:0005739=GO_REF:0000054, GO:0003735=PMID:11543634, GO:0005761=PMID:11543634, GO:0008097=PMID:21685364, GO:0006412=PMID:11543634, GO:0035928=PMID:21685364} Q9H0U6 39S ribosomal protein L18, mitochondrial protein 20100607 {GO:0005739=IDA, GO:0003735=NAS, GO:0005761=NAS, GO:0008097=IDA, GO:0006412=NAS, GO:0035928=IDA} rRNA import into mitochondrion, translation mitochondrial ribosome, mitochondrion 5S rRNA binding, structural constituent of ribosome Human MRPL19 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0031965=PMID:10942595, GO:0003735=GO_REF:0000002, GO:0005840=GO_REF:0000037, GO:0005634=PMID:10942595, GO:0006412=GO_REF:0000002} P49406 39S ribosomal protein L19, mitochondrial protein 20060117 {GO:0005739=IEA, GO:0031965=IDA, GO:0003735=IEA, GO:0005840=IEA, GO:0005634=IDA, GO:0006412=IEA} translation mitochondrion, nuclear membrane, nucleus, ribosome structural constituent of ribosome Human MRPL2 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0003735=GO_REF:0000002, GO:0005840=GO_REF:0000037, GO:0006412=GO_REF:0000002} Q5T653 39S ribosomal protein L2, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0003735=IEA, GO:0005840=IEA, GO:0006412=IEA} translation mitochondrion, ribosome structural constituent of ribosome Human UniProtKB-SubCell:SL-0173 MRPL20 UniProtKB UniProtKB {GO:0005515=PMID:20601428, GO:0003735=GO_REF:0000002, GO:0005761=PMID:20601428, GO:0005840=GO_REF:0000002, GO:0019843=GO_REF:0000002, GO:0006412=GO_REF:0000002} Q9BYC9 39S ribosomal protein L20, mitochondrial protein 20110629 {GO:0005515=IPI, GO:0003735=IEA, GO:0005761=IDA, GO:0005840=IEA, GO:0019843=IEA, GO:0006412=IEA} translation mitochondrial ribosome, ribosome protein binding, rRNA binding, structural constituent of ribosome Human MRPL21 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0003735=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0005840=GO_REF:0000037, GO:0006412=GO_REF:0000002} Q7Z2W9 39S ribosomal protein L21, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0003735=IEA, GO:0003723=IEA, GO:0005840=IEA, GO:0006412=IEA} translation mitochondrion, ribosome RNA binding, structural constituent of ribosome Human UniProtKB-SubCell:SL-0173 MRPL22 UniProtKB UniProtKB {GO:0005739=GO_REF:0000024, GO:0003735=GO_REF:0000002, GO:0015934=GO_REF:0000002, GO:0006412=GO_REF:0000002} Q9NWU5 39S ribosomal protein L22, mitochondrial protein 20080314 {GO:0005739=ISS, GO:0003735=IEA, GO:0015934=IEA, GO:0006412=IEA} translation large ribosomal subunit, mitochondrion structural constituent of ribosome Human UniProtKB:Q3SZX5 MRPL23 PINC UniProtKB {GO:0003735=GO_REF:0000002, GO:0000166=GO_REF:0000002, GO:0003723=PMID:8541832, GO:0005840=GO_REF:0000002, GO:0006412=GO_REF:0000002, GO:0005762=PMID:8541832} Q16540 39S ribosomal protein L23, mitochondrial protein 20030904 {GO:0003735=IEA, GO:0000166=IEA, GO:0003723=TAS, GO:0005840=IEA, GO:0006412=IEA, GO:0005762=TAS} translation mitochondrial large ribosomal subunit, ribosome RNA binding, nucleotide binding, structural constituent of ribosome Human MRPL24 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0003735=GO_REF:0000002, GO:0005840=GO_REF:0000037, GO:0006412=GO_REF:0000002} Q96A35 39S ribosomal protein L24, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0003735=IEA, GO:0005840=IEA, GO:0006412=IEA} translation mitochondrion, ribosome structural constituent of ribosome Human UniProtKB-SubCell:SL-0173 MRPL27 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0003735=PMID:11279069, GO:0005840=GO_REF:0000002, GO:0006412=PMID:11279069, GO:0005762=PMID:11279069} Q9P0M9 39S ribosomal protein L27, mitochondrial protein 20020904 {GO:0005739=IEA, GO:0003735=NAS, GO:0005840=IEA, GO:0006412=NAS, GO:0005762=NAS} translation mitochondrial large ribosomal subunit, mitochondrion, ribosome structural constituent of ribosome Human MRPL28 HPA UniProtKB {GO:0005515=PMID:20601428, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0003735=GO_REF:0000002, GO:0005761=PMID:20601428, GO:0006412=PMID:11543634} Q4TT38 39S ribosomal protein L28, mitochondrial protein 20101115 {GO:0005515=IPI, GO:0005739=IDA, GO:0005737=IDA, GO:0003735=IEA, GO:0005761=IDA, GO:0006412=NAS} translation cytoplasm, mitochondrial ribosome, mitochondrion protein binding, structural constituent of ribosome Human MRPL3 PINC UniProtKB {GO:0005739=GO_REF:0000019, GO:0003735=GO_REF:0000002, GO:0003723=PMID:2891103, GO:0005840=GO_REF:0000038, GO:0006412=GO_REF:0000002, GO:0005762=PMID:20186120} P09001 39S ribosomal protein L3, mitochondrial protein 20030904 {GO:0005739=IEA, GO:0003735=IEA, GO:0003723=TAS, GO:0005840=IEA, GO:0006412=IEA, GO:0005762=IDA} translation mitochondrial large ribosomal subunit, mitochondrion, ribosome RNA binding, structural constituent of ribosome Human MRPL30 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0005840=GO_REF:0000037} Q8TCC3 39S ribosomal protein L30, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0005840=IEA} mitochondrion, ribosome Human UniProtKB-SubCell:SL-0173 MRPL32 UniProtKB UniProtKB {GO:0003735=PMID:11543634, GO:0005761=PMID:11543634, GO:0015934=GO_REF:0000002, GO:0005840=GO_REF:0000038, GO:0006412=PMID:11543634} Q9BYC8 39S ribosomal protein L32, mitochondrial protein 20060301 {GO:0003735=NAS, GO:0005761=NAS, GO:0015934=IEA, GO:0005840=IEA, GO:0006412=NAS} translation large ribosomal subunit, mitochondrial ribosome, ribosome structural constituent of ribosome Human MRPL33 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0003735=GO_REF:0000002, GO:0005840=GO_REF:0000037, GO:0006412=GO_REF:0000002} O75394 39S ribosomal protein L33, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0003735=IEA, GO:0005840=IEA, GO:0006412=IEA} translation mitochondrion, ribosome structural constituent of ribosome Human UniProtKB-SubCell:SL-0173 MRPL34 UniProtKB UniProtKB {GO:0003735=PMID:11543634, GO:0005761=PMID:11543634, GO:0005840=GO_REF:0000002, GO:0006412=PMID:11543634} Q9BQ48 39S ribosomal protein L34, mitochondrial protein 20060301 {GO:0003735=NAS, GO:0005761=NAS, GO:0005840=IEA, GO:0006412=NAS} translation mitochondrial ribosome, ribosome structural constituent of ribosome Human MRPL35 UniProtKB UniProtKB {GO:0003735=PMID:11543634, GO:0005761=PMID:11543634, GO:0005840=GO_REF:0000002, GO:0006412=PMID:11543634} Q9NZE8 39S ribosomal protein L35, mitochondrial protein 20060301 {GO:0003735=NAS, GO:0005761=NAS, GO:0005840=IEA, GO:0006412=NAS} translation mitochondrial ribosome, ribosome structural constituent of ribosome Human MRPL36 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0003735=GO_REF:0000002, GO:0005840=GO_REF:0000002, GO:0006412=PMID:11279069, GO:0005762=PMID:11279069} Q9P0J6 39S ribosomal protein L36, mitochondrial protein 20021104 {GO:0005739=IEA, GO:0003735=IEA, GO:0005840=IEA, GO:0006412=NAS, GO:0005762=NAS} translation mitochondrial large ribosomal subunit, mitochondrion, ribosome structural constituent of ribosome Human MRPL37 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0003735=PMID:11543634, GO:0005761=PMID:11543634, GO:0005840=GO_REF:0000002, GO:0006412=PMID:11543634} Q9BZE1 39S ribosomal protein L37, mitochondrial protein 20111111 {GO:0005739=IDA, GO:0003735=NAS, GO:0005761=NAS, GO:0005840=IEA, GO:0006412=NAS} translation mitochondrial ribosome, mitochondrion, ribosome structural constituent of ribosome Human MRPL38 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0005840=GO_REF:0000037, GO:0015629=GO_REF:0000052} Q96DV4 39S ribosomal protein L38, mitochondrial protein 20101115 {GO:0005739=IDA, GO:0005737=IDA, GO:0005840=IEA, GO:0015629=IDA} actin cytoskeleton, cytoplasm, mitochondrion, ribosome Human MRPL39 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0000166=GO_REF:0000002, GO:0005761=PMID:11167009} Q9NYK5 39S ribosomal protein L39, mitochondrial protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0000166=IEA, GO:0005761=NAS} biological_process mitochondrial ribosome molecular_function, nucleotide binding Human MRPL4 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0003735=GO_REF:0000002, GO:0005840=GO_REF:0000037, GO:0006412=GO_REF:0000002} Q9BYD3 39S ribosomal protein L4, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0003735=IEA, GO:0005840=IEA, GO:0006412=IEA} translation mitochondrion, ribosome structural constituent of ribosome Human UniProtKB-SubCell:SL-0173 MRPL40 PINC UniProtKB {GO:0003674=GO_REF:0000015, GO:0005761=GO_REF:0000024, GO:0005634=PMID:9790763, GO:0009653=PMID:9790763} Q9NQ50 39S ribosomal protein L40, mitochondrial protein 20050308 {GO:0003674=ND, GO:0005761=ISS, GO:0005634=TAS, GO:0009653=TAS} anatomical structure morphogenesis mitochondrial ribosome, nucleus molecular_function Human MRPL41 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0007049=GO_REF:0000037, GO:0003735=PMID:16024796, GO:0030529=PMID:16024796, GO:0006915=GO_REF:0000037, GO:0006412=PMID:16024796, GO:0005762=PMID:16024796} Q8IXM3 39S ribosomal protein L41, mitochondrial protein 20101115 {GO:0005739=IDA, GO:0007049=IEA, GO:0003735=IDA, GO:0030529=IDA, GO:0006915=IEA, GO:0006412=IDA, GO:0005762=IDA} apoptotic process, cell cycle, translation mitochondrial large ribosomal subunit, mitochondrion, ribonucleoprotein complex structural constituent of ribosome Human MRPL42 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0003735=PMID:11279123, GO:0005886=GO_REF:0000052, GO:0005840=GO_REF:0000038, GO:0006412=PMID:11279123, GO:0005763=PMID:11279123} Q9Y6G3 39S ribosomal protein L42, mitochondrial protein 20110516 {GO:0005739=IDA, GO:0003735=NAS, GO:0005886=IDA, GO:0005840=IEA, GO:0006412=NAS, GO:0005763=IDA} translation mitochondrial small ribosomal subunit, mitochondrion, plasma membrane, ribosome structural constituent of ribosome Human MRPL43 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0003735=PMID:11543634, GO:0005761=PMID:11543634, GO:0005840=GO_REF:0000038, GO:0006412=PMID:11543634} Q8N983 39S ribosomal protein L43, mitochondrial protein 20060301 {GO:0005739=IEA, GO:0003735=NAS, GO:0005761=NAS, GO:0005840=IEA, GO:0006412=NAS} translation mitochondrial ribosome, mitochondrion, ribosome structural constituent of ribosome Human MRPL44 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0003725=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0006396=GO_REF:0000002, GO:0004525=GO_REF:0000002, GO:0005840=GO_REF:0000037, GO:0005575=GO_REF:0000015} Q9H9J2 39S ribosomal protein L44, mitochondrial protein 20061026 {GO:0005739=IEA, GO:0003725=IEA, GO:0003674=ND, GO:0008150=ND, GO:0006396=IEA, GO:0004525=IEA, GO:0005840=IEA, GO:0005575=ND} RNA processing, biological_process cellular_component, mitochondrion, ribosome double-stranded RNA binding, molecular_function, ribonuclease III activity Human MRPL45 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0003735=GO_REF:0000029, GO:0005840=GO_REF:0000037, GO:0006412=GO_REF:0000029} Q9BRJ2 39S ribosomal protein L45, mitochondrial protein 20100326 {GO:0005739=IDA, GO:0003735=NAS, GO:0005840=IEA, GO:0006412=NAS} translation mitochondrion, ribosome structural constituent of ribosome Human MRPL46 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0016787=GO_REF:0000002, GO:0005840=GO_REF:0000037, GO:0005575=GO_REF:0000015} Q9H2W6 39S ribosomal protein L46, mitochondrial protein 20061026 {GO:0005739=IEA, GO:0003674=ND, GO:0008150=ND, GO:0016787=IEA, GO:0005840=IEA, GO:0005575=ND} biological_process cellular_component, mitochondrion, ribosome hydrolase activity, molecular_function Human MRPL47 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0003735=GO_REF:0000002, GO:0005761=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0006412=GO_REF:0000002} Q9HD33 39S ribosomal protein L47, mitochondrial protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0003735=IEA, GO:0005761=IEA, GO:0005575=ND, GO:0006412=IEA} biological_process, translation cellular_component, mitochondrial ribosome molecular_function, structural constituent of ribosome Human MRPL48 UniProtKB UniProtKB {GO:0005515=PMID:20601428, GO:0005761=PMID:20601428} Q96GC5 39S ribosomal protein L48, mitochondrial protein 20110629 {GO:0005515=IPI, GO:0005761=IDA} mitochondrial ribosome protein binding Human MRPL49 UniProtKB UniProtKB {GO:0005515=PMID:20601428, GO:0003735=GO_REF:0000002, GO:0005761=PMID:20601428, GO:0005840=GO_REF:0000002, GO:0006412=GO_REF:0000002} Q13405 39S ribosomal protein L49, mitochondrial protein 20110629 {GO:0005515=IPI, GO:0003735=IEA, GO:0005761=IDA, GO:0005840=IEA, GO:0006412=IEA} translation mitochondrial ribosome, ribosome protein binding, structural constituent of ribosome Human MRPL50 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0005840=GO_REF:0000037} Q8N5N7 39S ribosomal protein L50, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0005840=IEA} mitochondrion, ribosome Human UniProtKB-SubCell:SL-0173 MRPL51 UniProtKB UniProtKB {GO:0005515=PMID:20601428, GO:0003735=GO_REF:0000024, GO:0005761=PMID:20601428, GO:0006412=GO_REF:0000024, GO:0005762=GO_REF:0000024} Q4U2R6 39S ribosomal protein L51, mitochondrial protein 20110629 {GO:0005515=IPI, GO:0003735=ISS, GO:0005761=IDA, GO:0006412=ISS, GO:0005762=ISS} translation mitochondrial large ribosomal subunit, mitochondrial ribosome protein binding, structural constituent of ribosome Human MRPL52 UniProtKB UniProtKB {GO:0003735=GO_REF:0000024, GO:0005840=GO_REF:0000038, GO:0006412=GO_REF:0000024, GO:0005762=GO_REF:0000024} Q86TS9 39S ribosomal protein L52, mitochondrial protein 20070220 {GO:0003735=ISS, GO:0005840=IEA, GO:0006412=ISS, GO:0005762=ISS} translation mitochondrial large ribosomal subunit, ribosome structural constituent of ribosome Human UniProtKB:P0C2B7 MRPL53 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0005840=GO_REF:0000037} Q96EL3 39S ribosomal protein L53, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0005840=IEA} mitochondrion, ribosome Human UniProtKB-SubCell:SL-0173 MRPL54 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0005840=GO_REF:0000037} Q6P161 39S ribosomal protein L54, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0005840=IEA} mitochondrion, ribosome Human UniProtKB-SubCell:SL-0173 MRPL55 UniProtKB UniProtKB {GO:0003735=GO_REF:0000024, GO:0006412=GO_REF:0000024, GO:0005762=GO_REF:0000024} Q7Z7F7 39S ribosomal protein L55, mitochondrial protein 20070220 {GO:0003735=ISS, GO:0006412=ISS, GO:0005762=ISS} translation mitochondrial large ribosomal subunit structural constituent of ribosome Human UniProtKB:P0C2B8 MRPL9 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0003735=PMID:11543634, GO:0005761=PMID:11543634, GO:0005840=GO_REF:0000002, GO:0006412=PMID:11543634} Q9BYD2 39S ribosomal protein L9, mitochondrial protein 20080205 {GO:0005739=IDA, GO:0003735=NAS, GO:0005761=NAS, GO:0005840=IEA, GO:0006412=NAS} translation mitochondrial ribosome, mitochondrion, ribosome structural constituent of ribosome Human MRPS10 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005840=GO_REF:0000037} P82664 28S ribosomal protein S10, mitochondrial protein 20081030 {GO:0005739=IEA, GO:0003674=ND, GO:0008150=ND, GO:0005840=IEA} biological_process mitochondrion, ribosome molecular_function Human MRPS11 MGI UniProtKB {GO:0003735=GO_REF:0000002, GO:0042769=PMID:15300802, GO:0005840=GO_REF:0000002, GO:0006412=GO_REF:0000002, GO:0005763=PMID:21531335} P82912 28S ribosomal protein S11, mitochondrial protein 20111227 {GO:0003735=IEA, GO:0042769=NAS, GO:0005840=IEA, GO:0006412=IEA, GO:0005763=IDA} DNA damage response, detection of DNA damage, translation mitochondrial small ribosomal subunit, ribosome structural constituent of ribosome Human MRPS12 IntAct UniProtKB {GO:0005515=PMID:12970870, GO:0003735=GO_REF:0000002, GO:0005761=PMID:9545647, GO:0015935=GO_REF:0000002, GO:0006412=GO_REF:0000002} O15235 28S ribosomal protein S12, mitochondrial protein 20130415 {GO:0005515=IPI, GO:0003735=IEA, GO:0005761=TAS, GO:0015935=IEA, GO:0006412=IEA} translation mitochondrial ribosome, small ribosomal subunit protein binding, structural constituent of ribosome Human UniProtKB:P58062 MRPS14 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0031965=GO_REF:0000052, GO:0003735=PMID:10938081, GO:0005761=PMID:10938081, GO:0006412=PMID:10938081} O60783 28S ribosomal protein S14, mitochondrial protein 20120912 {GO:0005739=IDA, GO:0031965=IDA, GO:0003735=TAS, GO:0005761=NAS, GO:0006412=NAS} translation mitochondrial ribosome, mitochondrion, nuclear membrane structural constituent of ribosome Human MRPS15 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0031965=GO_REF:0000052, GO:0003735=PMID:11279123, GO:0006412=PMID:11279123, GO:0005763=PMID:11279123} P82914 28S ribosomal protein S15, mitochondrial protein 20101115 {GO:0005739=IDA, GO:0031965=IDA, GO:0003735=NAS, GO:0006412=NAS, GO:0005763=IDA} translation mitochondrial small ribosomal subunit, mitochondrion, nuclear membrane structural constituent of ribosome Human MRPS16 UniProtKB UniProtKB {GO:0005515=PMID:19945174, GO:0003735=PMID:11279123, GO:0005840=GO_REF:0000038, GO:0006412=PMID:11279123, GO:0005763=PMID:11279123} Q9Y3D3 28S ribosomal protein S16, mitochondrial protein 20110208 {GO:0005515=IPI, GO:0003735=NAS, GO:0005840=IEA, GO:0006412=NAS, GO:0005763=IDA} translation mitochondrial small ribosomal subunit, ribosome protein binding, structural constituent of ribosome Human UniProtKB:P21754 MRPS17 UniProtKB UniProtKB {GO:0006355=GO_REF:0000002, GO:0003735=PMID:11279123, GO:0005840=GO_REF:0000002, GO:0019843=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0006412=PMID:11279123, GO:0005763=PMID:11279123} Q9Y2R5 28S ribosomal protein S17, mitochondrial protein 20010810 {GO:0006355=IEA, GO:0003735=NAS, GO:0005840=IEA, GO:0019843=IEA, GO:0003676=IEA, GO:0006412=NAS, GO:0005763=NAS} regulation of transcription, DNA-dependent, translation mitochondrial small ribosomal subunit, ribosome nucleic acid binding, rRNA binding, structural constituent of ribosome Human MRPS18A UniProtKB UniProtKB {GO:0003735=PMID:11279123, GO:0005840=GO_REF:0000002, GO:0006412=PMID:11279123, GO:0005763=PMID:11279123} Q9NVS2 28S ribosomal protein S18a, mitochondrial protein 20010817 {GO:0003735=NAS, GO:0005840=IEA, GO:0006412=NAS, GO:0005763=IDA} translation mitochondrial small ribosomal subunit, ribosome structural constituent of ribosome Human MRPS18B UniProtKB UniProtKB {GO:0003735=PMID:11279123, GO:0005840=GO_REF:0000002, GO:0006412=PMID:11279123, GO:0005763=PMID:11279123} Q9Y676 28S ribosomal protein S18b, mitochondrial protein 20021104 {GO:0003735=NAS, GO:0005840=IEA, GO:0006412=NAS, GO:0005763=NAS} translation mitochondrial small ribosomal subunit, ribosome structural constituent of ribosome Human MRPS18C UniProtKB UniProtKB {GO:0003735=PMID:11279123, GO:0005840=GO_REF:0000002, GO:0006412=PMID:11279123, GO:0005763=PMID:11279123} Q9Y3D5 28S ribosomal protein S18c, mitochondrial protein 20010817 {GO:0003735=NAS, GO:0005840=IEA, GO:0006412=NAS, GO:0005763=IDA} translation mitochondrial small ribosomal subunit, ribosome structural constituent of ribosome Human MRPS2 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0003735=GO_REF:0000002, GO:0015935=GO_REF:0000002, GO:0006412=GO_REF:0000002} Q9Y399 28S ribosomal protein S2, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0003735=IEA, GO:0015935=IEA, GO:0006412=IEA} translation mitochondrion, small ribosomal subunit structural constituent of ribosome Human UniProtKB-SubCell:SL-0173 MRPS21 UniProtKB UniProtKB {GO:0003735=PMID:11279123, GO:0006412=PMID:11279123, GO:0005763=PMID:11279123} P82921 28S ribosomal protein S21, mitochondrial protein 20010817 {GO:0003735=NAS, GO:0006412=NAS, GO:0005763=IDA} translation mitochondrial small ribosomal subunit structural constituent of ribosome Human MRPS22 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0008150=GO_REF:0000015, GO:0003735=PMID:10938081, GO:0005761=PMID:10938081, GO:0005840=GO_REF:0000038, GO:0005763=PMID:10938081} Q9H3I1 28S ribosomal protein S22, mitochondrial protein 20080205 {GO:0005739=IDA, GO:0008150=ND, GO:0003735=IDA, GO:0005761=NAS, GO:0005840=IEA, GO:0005763=IDA} biological_process mitochondrial ribosome, mitochondrial small ribosomal subunit, mitochondrion, ribosome structural constituent of ribosome Human MRPS23 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0031965=GO_REF:0000052, GO:0003735=GO_REF:0000002, GO:0005840=GO_REF:0000037, GO:0045111=GO_REF:0000052, GO:0006412=GO_REF:0000002} Q9Y3D9 28S ribosomal protein S23, mitochondrial protein 20100326 {GO:0005739=IDA, GO:0031965=IDA, GO:0003735=IEA, GO:0005840=IEA, GO:0045111=IDA, GO:0006412=IEA} translation intermediate filament cytoskeleton, mitochondrion, nuclear membrane, ribosome structural constituent of ribosome Human MRPS24 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0003735=GO_REF:0000024, GO:0006412=GO_REF:0000024, GO:0005763=PMID:10938081, GO:0005762=GO_REF:0000024} Q96EL2 28S ribosomal protein S24, mitochondrial protein 20070220 {GO:0008150=ND, GO:0003674=ND, GO:0003735=ISS, GO:0006412=ISS, GO:0005763=NAS, GO:0005762=ISS} biological_process, translation mitochondrial large ribosomal subunit, mitochondrial small ribosomal subunit molecular_function, structural constituent of ribosome Human UniProtKB:Q2M2T7 MRPS25 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0003735=GO_REF:0000029, GO:0005840=GO_REF:0000038, GO:0006412=GO_REF:0000029, GO:0005763=GO_REF:0000029} P82663 28S ribosomal protein S25, mitochondrial protein 20110516 {GO:0005739=IDA, GO:0005737=IDA, GO:0003735=NAS, GO:0005840=IEA, GO:0006412=NAS, GO:0005763=NAS} translation cytoplasm, mitochondrial small ribosomal subunit, mitochondrion, ribosome structural constituent of ribosome Human MRPS26 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0042769=PMID:15300802, GO:0043043=PMID:11279123, GO:0005763=PMID:11279123} Q9BYN8 28S ribosomal protein S26, mitochondrial protein 20120912 {GO:0005739=IDA, GO:0042769=NAS, GO:0043043=IC, GO:0005763=NAS} DNA damage response, detection of DNA damage, peptide biosynthetic process mitochondrial small ribosomal subunit, mitochondrion Human MRPS27 UniProtKB UniProtKB {GO:0005515=PMID:19103604, GO:0005739=GO_REF:0000039, GO:0005840=GO_REF:0000037} Q92552 28S ribosomal protein S27, mitochondrial protein 20120708 {GO:0005515=IPI, GO:0005739=IEA, GO:0005840=IEA} mitochondrion, ribosome protein binding Human UniProtKB:Q8NC60 MRPS28 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005763=PMID:10938081} Q9Y2Q9 28S ribosomal protein S28, mitochondrial protein 20100326 {GO:0005739=IDA, GO:0003674=ND, GO:0008150=ND, GO:0005763=TAS} biological_process mitochondrial small ribosomal subunit, mitochondrion molecular_function Human MRPS30 PINC UniProtKB {GO:0005739=GO_REF:0000039, GO:0003735=GO_REF:0000002, GO:0006915=PMID:10640817, GO:0005840=GO_REF:0000037, GO:0006412=GO_REF:0000002} Q9NP92 28S ribosomal protein S30, mitochondrial protein 20030904 {GO:0005739=IEA, GO:0003735=IEA, GO:0006915=TAS, GO:0005840=IEA, GO:0006412=IEA} apoptotic process, translation mitochondrion, ribosome structural constituent of ribosome Human MRPS31 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0005739=PMID:8567980, GO:0003735=GO_REF:0000002, GO:0019904=PMID:11984006, GO:0005763=GO_REF:0000002} Q92665 28S ribosomal protein S31, mitochondrial protein 20130415 {GO:0005515=IPI, GO:0005739=TAS, GO:0003735=IEA, GO:0019904=IPI, GO:0005763=IEA} mitochondrial small ribosomal subunit, mitochondrion protein binding, protein domain specific binding, structural constituent of ribosome Human UniProtKB:P40763 MRPS33 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0003735=PMID:11279123, GO:0006412=PMID:11279123, GO:0005763=PMID:11279123} Q9Y291 28S ribosomal protein S33, mitochondrial protein 20021113 {GO:0005739=IEA, GO:0003735=NAS, GO:0006412=NAS, GO:0005763=NAS} translation mitochondrial small ribosomal subunit, mitochondrion structural constituent of ribosome Human MRPS34 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005840=GO_REF:0000037} P82930 28S ribosomal protein S34, mitochondrial protein 20110516 {GO:0005739=IDA, GO:0005840=IEA} mitochondrion, ribosome Human MRPS35 UniProtKB UniProtKB {GO:0042769=PMID:15300802, GO:0043043=PMID:11279123, GO:0005763=GO_REF:0000024} P82673 28S ribosomal protein S35, mitochondrial protein 20060116 {GO:0042769=NAS, GO:0043043=IC, GO:0005763=ISS} DNA damage response, detection of DNA damage, peptide biosynthetic process mitochondrial small ribosomal subunit Human UniProtKB:Q2YDF6 MRPS36 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0003735=PMID:11279123, GO:0006412=PMID:11279123, GO:0005763=PMID:11279123} P82909 28S ribosomal protein S36, mitochondrial protein 20101115 {GO:0005739=IDA, GO:0003735=NAS, GO:0006412=NAS, GO:0005763=IDA} translation mitochondrial small ribosomal subunit, mitochondrion structural constituent of ribosome Human MRPS5 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0003735=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0005840=GO_REF:0000037, GO:0006412=GO_REF:0000002} P82675 28S ribosomal protein S5, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0003735=IEA, GO:0003723=IEA, GO:0005840=IEA, GO:0006412=IEA} translation mitochondrion, ribosome RNA binding, structural constituent of ribosome Human UniProtKB-SubCell:SL-0173 MRPS6 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0003735=PMID:11279123, GO:0015935=PMID:11279123, GO:0019843=GO_REF:0000002, GO:0006412=PMID:11279123} P82932 28S ribosomal protein S6, mitochondrial protein 20010821 {GO:0005739=IEA, GO:0003735=NAS, GO:0015935=NAS, GO:0019843=IEA, GO:0006412=NAS} translation mitochondrion, small ribosomal subunit rRNA binding, structural constituent of ribosome Human MRPS7 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0003735=GO_REF:0000024, GO:0022627=GO_REF:0000024, GO:0003723=GO_REF:0000024, GO:0005840=GO_REF:0000002, GO:0006412=GO_REF:0000024} Q9Y2R9 28S ribosomal protein S7, mitochondrial protein 20101115 {GO:0005739=IDA, GO:0003735=ISS, GO:0022627=ISS, GO:0003723=ISS, GO:0005840=IEA, GO:0006412=ISS} translation cytosolic small ribosomal subunit, mitochondrion, ribosome RNA binding, structural constituent of ribosome Human MRPS9 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0003735=GO_REF:0000002, GO:0042769=PMID:15300802, GO:0043043=PMID:11279123, GO:0006412=GO_REF:0000002, GO:0005763=PMID:11279123} P82933 28S ribosomal protein S9, mitochondrial protein 20130415 {GO:0005515=IPI, GO:0003735=IEA, GO:0042769=NAS, GO:0043043=IC, GO:0006412=IEA, GO:0005763=NAS} DNA damage response, detection of DNA damage, peptide biosynthetic process, translation mitochondrial small ribosomal subunit protein binding, structural constituent of ribosome Human UniProtKB:P04618 MRRF UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0032790=PMID:19716793, GO:0006412=GO_REF:0000037} Q96E11 Ribosome-recycling factor, mitochondrial protein 20090902 {GO:0005739=IEA, GO:0032790=IDA, GO:0006412=IEA} ribosome disassembly, translation mitochondrion Human MRS2 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0005743=GO_REF:0000039, GO:0015095=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q9HD23 Magnesium transporter MRS2 homolog, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0005743=IEA, GO:0015095=IEA, GO:0016021=IEA} integral to membrane, mitochondrial inner membrane, mitochondrion magnesium ion transmembrane transporter activity Human UniProtKB-SubCell:SL-0168 MRTO4 HPA UniProtKB {GO:0031965=GO_REF:0000052, GO:0042254=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9UKD2 mRNA turnover protein 4 homolog protein 20100326 {GO:0031965=IDA, GO:0042254=IEA, GO:0005730=IDA, GO:0005634=IDA} ribosome biogenesis nuclear membrane, nucleolus, nucleus Human MRVI1 Reactome UniProtKB {GO:0005515=PMID:16990611, GO:0048471=GO_REF:0000039, GO:0016529=GO_REF:0000039, GO:0007596=Reactome:REACT_604, GO:0005789=PMID:10321731, GO:0016021=GO_REF:0000037, GO:0031095=Reactome:REACT_24000} Q9Y6F6 Protein MRVI1 protein 20090422 {GO:0005515=IPI, GO:0048471=IEA, GO:0016529=IEA, GO:0007596=TAS, GO:0005789=TAS, GO:0016021=IEA, GO:0031095=TAS} blood coagulation endoplasmic reticulum membrane, integral to membrane, perinuclear region of cytoplasm, platelet dense tubular network membrane, sarcoplasmic reticulum protein binding Human MS4A1 HPA UniProtKB {GO:0042113=GO_REF:0000037, GO:0006955=PMID:7920628, GO:0005886=PMID:1535625, GO:0005887=PMID:1535625, GO:0005730=GO_REF:0000052, GO:0016021=GO_REF:0000002, GO:0009897=GO_REF:0000019} P11836 B-lymphocyte antigen CD20 protein 20101115 {GO:0042113=IEA, GO:0006955=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0005730=IDA, GO:0016021=IEA, GO:0009897=IEA} B cell activation, immune response external side of plasma membrane, integral to membrane, integral to plasma membrane, nucleolus, plasma membrane Human MS4A2 GOC UniProtKB {GO:0051219=GO_REF:0000019, GO:0005262=PMID:9169438, GO:0050663=GO_REF:0000019, GO:0019901=GO_REF:0000019, GO:0008283=PMID:2448768, GO:0051279=GO_REF:0000019, GO:0007202=GO_REF:0000019, GO:0007205=GO_REF:0000019, GO:0043306=GO_REF:0000019, GO:0032998=GO_REF:0000019, GO:0019863=GO_REF:0000019, GO:0006954=GO_REF:0000019, GO:0007186=PMID:9169438, GO:0005887=GO_REF:0000019, GO:0006959=PMID:2448768, GO:0070588=PMID:9169438, GO:0045121=GO_REF:0000019, GO:0042169=GO_REF:0000019, GO:0009897=GO_REF:0000019, GO:0005768=GO_REF:0000019} Q01362 High affinity immunoglobulin epsilon receptor subunit beta protein 20130413 {GO:0051219=IEA, GO:0005262=TAS, GO:0050663=IEA, GO:0019901=IEA, GO:0008283=TAS, GO:0051279=IEA, GO:0007202=IEA, GO:0007205=IEA, GO:0043306=IEA, GO:0032998=IEA, GO:0019863=IEA, GO:0006954=IEA, GO:0007186=TAS, GO:0005887=IEA, GO:0006959=TAS, GO:0070588=TAS, GO:0045121=IEA, GO:0042169=IEA, GO:0009897=IEA, GO:0005768=IEA} G-protein coupled receptor signaling pathway, activation of phospholipase C activity, calcium ion transmembrane transport, cell proliferation, cytokine secretion, humoral immune response, inflammatory response, positive regulation of mast cell degranulation, protein kinase C-activating G-protein coupled receptor signaling pathway, regulation of release of sequestered calcium ion into cytosol Fc-epsilon receptor I complex, endosome, external side of plasma membrane, integral to plasma membrane, membrane raft IgE binding, SH2 domain binding, calcium channel activity, phosphoprotein binding, protein kinase binding Human MS4A3 UniProtKB UniProtKB {GO:0005515=PMID:15671017, GO:0048471=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0012505=GO_REF:0000039} Q96HJ5 Membrane-spanning 4-domains subfamily A member 3 protein 20090511 {GO:0005515=IPI, GO:0048471=IEA, GO:0016021=IEA, GO:0012505=IEA} endomembrane system, integral to membrane, perinuclear region of cytoplasm protein binding Human UniProtKB:Q16667 MS4A5 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9H3V2 Membrane-spanning 4-domains subfamily A member 5 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 MS4A7 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9GZW8 Membrane-spanning 4-domains subfamily A member 7 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 MSC PINC UniProtKB {GO:0003700=PMID:9584154, GO:0006366=PMID:9584154, GO:0003714=PMID:9584154, GO:0060539=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0060021=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0014707=GO_REF:0000019, GO:0003677=GO_REF:0000037} O60682 Musculin protein 20030904 {GO:0003700=TAS, GO:0006366=TAS, GO:0003714=TAS, GO:0060539=IEA, GO:0046983=IEA, GO:0060021=IEA, GO:0005634=IEA, GO:0014707=IEA, GO:0003677=IEA} branchiomeric skeletal muscle development, diaphragm development, palate development, transcription from RNA polymerase II promoter nucleus DNA binding, protein dimerization activity, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human MSH2 GOC UniProtKB {GO:0005515=PMID:19596235, GO:0019724=GO_REF:0000024, GO:0032405=PMID:16403449, GO:0016446=GO_REF:0000033, GO:0007281=GO_REF:0000019, GO:0042803=PMID:8942985, GO:0006119=GO_REF:0000019, GO:0043524=GO_REF:0000024, GO:0003690=PMID:11809883, GO:0003697=PMID:11809883, GO:0006298=PMID:11555625, GO:0032357=PMID:11801590, GO:0008094=GO_REF:0000033, GO:0000400=PMID:12034830, GO:0000287=PMID:16403449, GO:0000404=GO_REF:0000033, GO:0019901=PMID:14657349, GO:0045190=GO_REF:0000024, GO:0000403=GO_REF:0000033, GO:0000406=GO_REF:0000033, GO:0001701=GO_REF:0000019, GO:0042771=GO_REF:0000033, GO:0006281=PMID:8942985, GO:0043531=PMID:15105434, GO:0016447=GO_REF:0000024, GO:0019899=PMID:14676842, GO:0030983=PMID:11801590, GO:0006200=PMID:16403449, GO:0010165=GO_REF:0000024, GO:0031573=GO_REF:0000033, GO:0008340=GO_REF:0000019, GO:0045128=GO_REF:0000033, GO:0006301=PMID:7923193, GO:0006302=GO_REF:0000033, GO:0051096=PMID:17715146, GO:0030183=GO_REF:0000024, GO:0007050=GO_REF:0000019, GO:0016887=PMID:16403449, GO:0032181=PMID:8942985, GO:0006915=GO_REF:0000019, GO:0019237=GO_REF:0000019, GO:0000228=GO_REF:0000033, GO:0006311=GO_REF:0000033, GO:0008022=PMID:14706347, GO:0005524=PMID:15105434, GO:0003677=PMID:7923193, GO:0032142=PMID:8942985, GO:0032143=PMID:8942985, GO:0043570=PMID:16388310, GO:0003684=GO_REF:0000019, GO:0032301=PMID:8942985, GO:0032302=PMID:8942985, GO:0000710=GO_REF:0000033, GO:0032137=PMID:11809883, GO:0010224=GO_REF:0000024, GO:0032139=PMID:8942985, GO:0045910=PMID:17715146, GO:0008584=GO_REF:0000024} P43246 DNA mismatch repair protein Msh2 protein 20130413 {GO:0005515=IPI, GO:0019724=ISS, GO:0032405=IDA, GO:0016446=IBA, GO:0007281=IEA, GO:0042803=IDA, GO:0006119=IEA, GO:0043524=ISS, GO:0003690=IDA, GO:0003697=IDA, GO:0006298=IDA, GO:0032357=IDA, GO:0008094=IBA, GO:0000400=IDA, GO:0000287=IDA, GO:0000404=IBA, GO:0019901=IPI, GO:0045190=ISS, GO:0000403=IBA, GO:0000406=IBA, GO:0001701=IEA, GO:0042771=IBA, GO:0006281=IDA, GO:0043531=IDA, GO:0016447=ISS, GO:0019899=IPI, GO:0030983=IDA, GO:0006200=IDA, GO:0010165=ISS, GO:0031573=IBA, GO:0008340=IEA, GO:0045128=IBA, GO:0006301=IDA, GO:0006302=IBA, GO:0051096=IDA, GO:0030183=ISS, GO:0007050=IEA, GO:0016887=IDA, GO:0032181=IDA, GO:0006915=IEA, GO:0019237=IEA, GO:0000228=IBA, GO:0006311=IBA, GO:0008022=IPI, GO:0005524=IDA, GO:0003677=IDA, GO:0032142=IDA, GO:0032143=IDA, GO:0043570=IMP, GO:0003684=IEA, GO:0032301=IDA, GO:0032302=IDA, GO:0000710=IBA, GO:0032137=IDA, GO:0010224=ISS, GO:0032139=IDA, GO:0045910=IDA, GO:0008584=ISS} ATP catabolic process, B cell differentiation, B cell mediated immunity, DNA repair, apoptotic process, cell cycle arrest, determination of adult lifespan, double-strand break repair, germ cell development, in utero embryonic development, intra-S DNA damage checkpoint, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, isotype switching, maintenance of DNA repeat elements, male gonad development, meiotic gene conversion, meiotic mismatch repair, mismatch repair, negative regulation of DNA recombination, negative regulation of neuron apoptotic process, negative regulation of reciprocal meiotic recombination, oxidative phosphorylation, positive regulation of helicase activity, postreplication repair, response to UV-B, response to X-ray, somatic hypermutation of immunoglobulin genes, somatic recombination of immunoglobulin gene segments MutSalpha complex, MutSbeta complex, nuclear chromosome ADP binding, ATP binding, ATPase activity, DNA binding, DNA-dependent ATPase activity, MutLalpha complex binding, Y-form DNA binding, centromeric DNA binding, damaged DNA binding, dinucleotide insertion or deletion binding, dinucleotide repeat insertion binding, double-strand/single-strand DNA junction binding, double-stranded DNA binding, enzyme binding, four-way junction DNA binding, guanine/thymine mispair binding, loop DNA binding, magnesium ion binding, mismatched DNA binding, oxidized purine DNA binding, protein C-terminus binding, protein binding, protein homodimerization activity, protein kinase binding, single guanine insertion binding, single thymine insertion binding, single-stranded DNA binding Human MSH3 HPA UniProtKB {GO:0005515=PMID:9774676, GO:0030983=PMID:8942985, GO:0005634=GO_REF:0000052, GO:0042803=PMID:8942985, GO:0003697=PMID:11809883, GO:0051096=PMID:17715146, GO:0006298=PMID:8782829, GO:0032357=PMID:11756455, GO:0008094=GO_REF:0000033, GO:0007131=GO_REF:0000033, GO:0032181=PMID:8942985, GO:0000404=GO_REF:0000033, GO:0000403=GO_REF:0000033, GO:0000406=GO_REF:0000033, GO:0019237=GO_REF:0000019, GO:0000228=GO_REF:0000033, GO:0005524=GO_REF:0000037, GO:0032142=PMID:8942985, GO:0043570=PMID:16388310, GO:0006281=PMID:8942985, GO:0032302=PMID:8942985, GO:0000710=GO_REF:0000033, GO:0032137=PMID:11809883, GO:0016447=GO_REF:0000033, GO:0032139=PMID:8942985, GO:0019899=PMID:11427529, GO:0045910=PMID:17715146} P20585 DNA mismatch repair protein Msh3 protein 20110516 {GO:0005515=IPI, GO:0030983=IDA, GO:0005634=IDA, GO:0042803=IDA, GO:0003697=IDA, GO:0051096=IDA, GO:0006298=IMP, GO:0032357=IDA, GO:0008094=IBA, GO:0007131=IBA, GO:0032181=IDA, GO:0000404=IBA, GO:0000403=IBA, GO:0000406=IBA, GO:0019237=IEA, GO:0000228=IBA, GO:0005524=IEA, GO:0032142=IDA, GO:0043570=IMP, GO:0006281=IDA, GO:0032302=IDA, GO:0000710=IBA, GO:0032137=IDA, GO:0016447=IBA, GO:0032139=IDA, GO:0019899=IPI, GO:0045910=IDA} DNA repair, maintenance of DNA repeat elements, meiotic mismatch repair, mismatch repair, negative regulation of DNA recombination, positive regulation of helicase activity, reciprocal meiotic recombination, somatic recombination of immunoglobulin gene segments MutSbeta complex, nuclear chromosome, nucleus ATP binding, DNA-dependent ATPase activity, Y-form DNA binding, centromeric DNA binding, dinucleotide insertion or deletion binding, dinucleotide repeat insertion binding, double-strand/single-strand DNA junction binding, enzyme binding, guanine/thymine mispair binding, loop DNA binding, mismatched DNA binding, oxidized purine DNA binding, protein binding, protein homodimerization activity, single guanine insertion binding, single-stranded DNA binding Human MSH4 PINC UniProtKB {GO:0030983=GO_REF:0000033, GO:0000795=GO_REF:0000033, GO:0005634=PMID:9299235, GO:0007283=GO_REF:0000019, GO:0007292=GO_REF:0000019, GO:0003677=PMID:9299235, GO:0005524=GO_REF:0000037, GO:0003684=GO_REF:0000033, GO:0001541=GO_REF:0000019, GO:0032300=GO_REF:0000033, GO:0000710=GO_REF:0000033, GO:0051026=GO_REF:0000033, GO:0045143=GO_REF:0000033, GO:0007131=GO_REF:0000033, GO:0008094=GO_REF:0000033} O15457 MutS protein homolog 4 protein 20030904 {GO:0030983=IBA, GO:0000795=IBA, GO:0005634=TAS, GO:0007283=IEA, GO:0007292=IEA, GO:0003677=TAS, GO:0005524=IEA, GO:0003684=IRD, GO:0001541=IEA, GO:0032300=IRD, GO:0000710=IRD, GO:0051026=IBA, GO:0045143=IBA, GO:0007131=IBA, GO:0008094=IBA} chiasma assembly, female gamete generation, homologous chromosome segregation, meiotic mismatch repair, ovarian follicle development, reciprocal meiotic recombination, spermatogenesis mismatch repair complex, nucleus, synaptonemal complex ATP binding, DNA binding, DNA-dependent ATPase activity, damaged DNA binding, mismatched DNA binding Human MSH5 PINC UniProtKB {GO:0030983=GO_REF:0000033, GO:0000795=GO_REF:0000033, GO:0005524=GO_REF:0000037, GO:0003684=GO_REF:0000033, GO:0032300=GO_REF:0000033, GO:0007136=PMID:9916805, GO:0007126=PMID:9740671, GO:0000710=GO_REF:0000033, GO:0051026=GO_REF:0000033, GO:0045143=GO_REF:0000033, GO:0006298=PMID:9740671, GO:0007131=GO_REF:0000033, GO:0008094=GO_REF:0000033} O43196 MutS protein homolog 5 protein 20030904 {GO:0030983=IBA, GO:0000795=IBA, GO:0005524=IEA, GO:0003684=IRD, GO:0032300=IRD, GO:0007136=TAS, GO:0007126=TAS, GO:0000710=IRD, GO:0051026=IBA, GO:0045143=IBA, GO:0006298=TAS, GO:0007131=IBA, GO:0008094=IBA} chiasma assembly, homologous chromosome segregation, meiosis, meiotic mismatch repair, meiotic prophase II, mismatch repair, reciprocal meiotic recombination mismatch repair complex, synaptonemal complex ATP binding, DNA-dependent ATPase activity, damaged DNA binding, mismatched DNA binding Human MSH6 GOC UniProtKB {GO:0005515=PMID:10856833, GO:0000790=GO_REF:0000019, GO:0030983=PMID:11801590, GO:0032405=PMID:16403449, GO:0006200=PMID:16403449, GO:0016446=GO_REF:0000024, GO:0008340=GO_REF:0000024, GO:0042803=PMID:8942985, GO:0003690=PMID:11809883, GO:0051096=PMID:17715146, GO:0006298=PMID:10871409, GO:0032357=PMID:11801590, GO:0009411=GO_REF:0000024, GO:0016887=PMID:16403449, GO:0007131=GO_REF:0000033, GO:0008094=GO_REF:0000033, GO:0000400=PMID:12034830, GO:0000287=PMID:16403449, GO:0008630=GO_REF:0000024, GO:0045190=GO_REF:0000024, GO:0000228=GO_REF:0000033, GO:0005524=PMID:15105434, GO:0097193=GO_REF:0000024, GO:0032142=PMID:8942985, GO:0043570=PMID:16388310, GO:0032143=PMID:8942985, GO:0003684=GO_REF:0000019, GO:0006281=PMID:8942985, GO:0032301=PMID:8942985, GO:0043531=PMID:15105434, GO:0000710=GO_REF:0000024, GO:0032137=PMID:11809883, GO:0003682=GO_REF:0000019, GO:0016447=GO_REF:0000024, GO:0045910=PMID:17715146} P52701 DNA mismatch repair protein Msh6 protein 20130413 {GO:0005515=IPI, GO:0000790=IEA, GO:0030983=IDA, GO:0032405=IDA, GO:0006200=IDA, GO:0016446=ISS, GO:0008340=ISS, GO:0042803=IPI, GO:0003690=IDA, GO:0051096=IDA, GO:0006298=IDA, GO:0032357=IDA, GO:0009411=ISS, GO:0016887=IDA, GO:0007131=IBA, GO:0008094=IBA, GO:0000400=IDA, GO:0000287=IDA, GO:0008630=ISS, GO:0045190=ISS, GO:0000228=IBA, GO:0005524=IDA, GO:0097193=ISS, GO:0032142=IDA, GO:0043570=IMP, GO:0032143=IDA, GO:0003684=IEA, GO:0006281=IDA, GO:0032301=IDA, GO:0043531=IDA, GO:0000710=ISS, GO:0032137=IDA, GO:0003682=IEA, GO:0016447=ISS, GO:0045910=IDA} ATP catabolic process, DNA repair, determination of adult lifespan, intrinsic apoptotic signaling pathway, intrinsic apoptotic signaling pathway in response to DNA damage, isotype switching, maintenance of DNA repeat elements, meiotic mismatch repair, mismatch repair, negative regulation of DNA recombination, positive regulation of helicase activity, reciprocal meiotic recombination, response to UV, somatic hypermutation of immunoglobulin genes, somatic recombination of immunoglobulin gene segments MutSalpha complex, nuclear chromatin, nuclear chromosome ADP binding, ATP binding, ATPase activity, DNA-dependent ATPase activity, MutLalpha complex binding, chromatin binding, damaged DNA binding, double-stranded DNA binding, four-way junction DNA binding, guanine/thymine mispair binding, magnesium ion binding, mismatched DNA binding, oxidized purine DNA binding, protein binding, protein homodimerization activity, single guanine insertion binding, single thymine insertion binding Human MSI1 PINC UniProtKB {GO:0008266=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0003723=PMID:9790759, GO:0030855=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0009725=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0005844=GO_REF:0000019, GO:0007399=PMID:9790759} O43347 RNA-binding protein Musashi homolog 1 protein 20030904 {GO:0008266=IEA, GO:0005737=IEA, GO:0000166=IEA, GO:0003723=TAS, GO:0030855=IEA, GO:0005634=IEA, GO:0009725=IEA, GO:0003676=IEA, GO:0005844=IEA, GO:0007399=TAS} epithelial cell differentiation, nervous system development, response to hormone stimulus cytoplasm, nucleus, polysome RNA binding, nucleic acid binding, nucleotide binding, poly(U) RNA binding Human MSI2 UniProtKB UniProtKB {GO:0008266=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0048864=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0005844=GO_REF:0000019} Q96DH6 RNA-binding protein Musashi homolog 2 protein 20130413 {GO:0008266=IEA, GO:0005737=IEA, GO:0000166=IEA, GO:0048864=IEA, GO:0003676=IEA, GO:0005844=IEA} stem cell development cytoplasm, polysome nucleic acid binding, nucleotide binding, poly(U) RNA binding Human UniProtKB-SubCell:SL-0086 MSL1 HPA UniProtKB {GO:0043984=PMID:20018852, GO:0005730=GO_REF:0000052, GO:0072487=PMID:20018852, GO:0005634=GO_REF:0000052} Q68DK7 Male-specific lethal 1 homolog protein 20100326 {GO:0043984=IDA, GO:0005730=IDA, GO:0072487=IDA, GO:0005634=IDA} histone H4-K16 acetylation MSL complex, nucleolus, nucleus NOT Human MSL2 UniProtKB UniProtKB {GO:0043984=PMID:20018852, GO:0016874=GO_REF:0000037, GO:0072487=PMID:20018852, GO:0008270=GO_REF:0000002} Q9HCI7 E3 ubiquitin-protein ligase MSL2 protein 20101217 {GO:0043984=IDA, GO:0016874=IEA, GO:0072487=IDA, GO:0008270=IEA} histone H4-K16 acetylation MSL complex ligase activity, zinc ion binding Human MSL3 PINC UniProtKB {GO:0003700=PMID:10395802, GO:0006366=PMID:10395802, GO:0043984=PMID:20018852, GO:0072487=PMID:20018852, GO:0007275=PMID:10395802, GO:0005634=PMID:10395802, GO:0035064=PMID:20657587, GO:0003677=PMID:20657587} Q8N5Y2 Male-specific lethal 3 homolog protein 20050308 {GO:0003700=TAS, GO:0006366=TAS, GO:0043984=IDA, GO:0072487=IDA, GO:0007275=TAS, GO:0005634=TAS, GO:0035064=IDA, GO:0003677=IDA} histone H4-K16 acetylation, multicellular organismal development, transcription from RNA polymerase II promoter MSL complex, nucleus DNA binding, methylated histone residue binding, sequence-specific DNA binding transcription factor activity Human MSLN UniProtKB UniProtKB {GO:0005515=PMID:14676194, GO:0005794=GO_REF:0000039, GO:0016020=PMID:8552591, GO:0005886=GO_REF:0000039, GO:0031016=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0031225=GO_REF:0000037, GO:0007155=PMID:8552591, GO:0005615=GO_REF:0000019} Q13421 Mesothelin protein 20120708 {GO:0005515=IPI, GO:0005794=IEA, GO:0016020=NAS, GO:0005886=IEA, GO:0031016=IEA, GO:0009986=IEA, GO:0031225=IEA, GO:0007155=NAS, GO:0005615=IEA} cell adhesion, pancreas development Golgi apparatus, anchored to membrane, cell surface, extracellular space, membrane, plasma membrane protein binding Human UniProtKB:Q8WXI7 MSMB PINC UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005634=PMID:7566962, GO:0005615=PMID:7566962} P08118 Beta-microseminoprotein protein 20030904 {GO:0003674=ND, GO:0008150=ND, GO:0005634=TAS, GO:0005615=TAS} biological_process extracellular space, nucleus molecular_function Human MSMO1 Reactome UniProtKB {GO:0006695=Reactome:REACT_9405, GO:0005886=PMID:8663358, GO:0005506=GO_REF:0000002, GO:0005783=PMID:8663358, GO:0005789=Reactome:REACT_10070, GO:0006631=PMID:8663358, GO:0016491=GO_REF:0000002, GO:0006633=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0008202=PMID:8663358, GO:0000254=GO_REF:0000003} Q15800 Methylsterol monooxygenase 1 protein 20130301 {GO:0006695=TAS, GO:0005886=TAS, GO:0005506=IEA, GO:0005783=TAS, GO:0005789=TAS, GO:0006631=TAS, GO:0016491=IEA, GO:0006633=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0008202=TAS, GO:0000254=IEA} cholesterol biosynthetic process, fatty acid biosynthetic process, fatty acid metabolic process, small molecule metabolic process, steroid metabolic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, plasma membrane C-4 methylsterol oxidase activity, iron ion binding, oxidoreductase activity Human MSN HPA UniProtKB {GO:0005515=PMID:21282464, GO:0008092=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0006928=PMID:16130169, GO:0031528=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0030175=PMID:12082081, GO:0050900=PMID:12082081, GO:0016323=GO_REF:0000019, GO:0016324=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0007159=PMID:12082081, GO:0022614=PMID:12082081, GO:0005856=PMID:16130169, GO:0050839=PMID:12082081, GO:0019901=PMID:19255442, GO:0005102=PMID:15819698, GO:0005730=GO_REF:0000052, GO:0045177=PMID:12082081, GO:2000401=PMID:19255442, GO:0005902=PMID:12082081, GO:0005200=PMID:1924289, GO:0001931=GO_REF:0000019, GO:0005925=PMID:21282464, GO:0019898=GO_REF:0000002} P26038 Moesin protein 20081203 {GO:0005515=IPI, GO:0008092=IEA, GO:0005886=IDA, GO:0006928=TAS, GO:0031528=IEA, GO:0005634=IDA, GO:0030175=IDA, GO:0050900=IEP, GO:0016323=IEA, GO:0016324=IEA, GO:0005737=IDA, GO:0007159=IEP, GO:0022614=IEP, GO:0005856=TAS, GO:0050839=IPI, GO:0019901=IPI, GO:0005102=IPI, GO:0005730=IDA, GO:0045177=IDA, GO:2000401=IMP, GO:0005902=IDA, GO:0005200=TAS, GO:0001931=IEA, GO:0005925=IDA, GO:0019898=IEA} cellular component movement, leukocyte cell-cell adhesion, leukocyte migration, membrane to membrane docking, regulation of lymphocyte migration apical part of cell, apical plasma membrane, basolateral plasma membrane, cytoplasm, cytoskeleton, extrinsic to membrane, filopodium, focal adhesion, microvillus, microvillus membrane, nucleolus, nucleus, plasma membrane, uropod cell adhesion molecule binding, cytoskeletal protein binding, protein binding, protein kinase binding, receptor binding, structural constituent of cytoskeleton Human MSR1 BHF-UCL UniProtKB {GO:0005515=PMID:17237231, GO:0005581=GO_REF:0000037, GO:0005886=GO_REF:0000019, GO:0010744=PMID:12376530, GO:0030169=PMID:12376530, GO:0030301=PMID:12376530, GO:0031410=GO_REF:0000019, GO:0010886=GO_REF:0000024, GO:0042221=GO_REF:0000019, GO:0006898=PMID:2251254, GO:0005829=GO_REF:0000019, GO:0042953=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0005887=PMID:8093617, GO:0034381=PMID:12376530, GO:0034362=GO_REF:0000037, GO:0005044=GO_REF:0000002} P21757 Macrophage scavenger receptor types I and II protein 20090629 {GO:0005515=IPI, GO:0005581=IEA, GO:0005886=IEA, GO:0010744=ISS, GO:0030169=ISS, GO:0030301=ISS, GO:0031410=IEA, GO:0010886=ISS, GO:0042221=IEA, GO:0006898=TAS, GO:0005829=IEA, GO:0042953=IEA, GO:0016020=IEA, GO:0005887=TAS, GO:0034381=ISS, GO:0034362=IEA, GO:0005044=IEA} cholesterol transport, lipoprotein transport, plasma lipoprotein particle clearance, positive regulation of cholesterol storage, positive regulation of macrophage derived foam cell differentiation, receptor-mediated endocytosis, response to chemical stimulus collagen, cytoplasmic vesicle, cytosol, integral to plasma membrane, low-density lipoprotein particle, membrane, plasma membrane low-density lipoprotein particle binding, protein binding, scavenger receptor activity Human UniProtKB:P30204 MSRA PINC UniProtKB {GO:0005739=GO_REF:0000039, GO:0008113=GO_REF:0000003, GO:0016020=GO_REF:0000039, GO:0006555=PMID:10452521, GO:0005634=GO_REF:0000039, GO:0006979=PMID:10452521, GO:0006464=PMID:10452521} Q9UJ68 Mitochondrial peptide methionine sulfoxide reductase protein 20030904 {GO:0005739=IEA, GO:0008113=IEA, GO:0016020=IEA, GO:0006555=TAS, GO:0005634=IEA, GO:0006979=TAS, GO:0006464=TAS} cellular protein modification process, methionine metabolic process, response to oxidative stress membrane, mitochondrion, nucleus peptide-methionine (S)-S-oxide reductase activity Human MSRB2 GOC UniProtKB {GO:0005739=PMID:14699060, GO:0006355=PMID:10375640, GO:0003700=PMID:10375640, GO:0030091=PMID:14699060, GO:0033743=PMID:14699060, GO:0008270=PMID:14699060} Q9Y3D2 Methionine-R-sulfoxide reductase B2, mitochondrial protein 20130413 {GO:0005739=ISS, GO:0006355=TAS, GO:0003700=TAS, GO:0030091=ISS, GO:0033743=ISS, GO:0008270=ISS} protein repair, regulation of transcription, DNA-dependent mitochondrion peptide-methionine (R)-S-oxide reductase activity, sequence-specific DNA binding transcription factor activity, zinc ion binding Human MST1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0004252=GO_REF:0000002, GO:0006508=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0005575=GO_REF:0000015} P26927 Hepatocyte growth factor-like protein protein 20100721 {GO:0003674=ND, GO:0008150=ND, GO:0004252=IEA, GO:0006508=IEA, GO:0005576=IEA, GO:0005575=ND} biological_process, proteolysis cellular_component, extracellular region molecular_function, serine-type endopeptidase activity Human MST1R GOC UniProtKB {GO:0038145=PMID:9045873, GO:0005515=PMID:15184888, GO:0008284=PMID:10871856, GO:0001725=GO_REF:0000019, GO:0006928=PMID:9045873, GO:0007275=GO_REF:0000002, GO:0006952=PMID:9045873, GO:0005524=GO_REF:0000037, GO:0007338=PMID:9045873, GO:0007165=PMID:7939629, GO:0005887=PMID:7939629, GO:0045087=GO_REF:0000037, GO:0005011=PMID:9045873, GO:0004872=GO_REF:0000002, GO:0004713=GO_REF:0000038, GO:0016021=GO_REF:0000038, GO:0019899=PMID:12676986, GO:0007169=GO_REF:0000002} Q04912 Macrophage-stimulating protein receptor protein 20130413 {GO:0038145=TAS, GO:0005515=IPI, GO:0008284=TAS, GO:0001725=IEA, GO:0006928=TAS, GO:0007275=IEA, GO:0006952=TAS, GO:0005524=IEA, GO:0007338=TAS, GO:0007165=TAS, GO:0005887=TAS, GO:0045087=IEA, GO:0005011=TAS, GO:0004872=IEA, GO:0004713=IEA, GO:0016021=IEA, GO:0019899=IPI, GO:0007169=IEA} cellular component movement, defense response, innate immune response, macrophage colony-stimulating factor signaling pathway, multicellular organismal development, positive regulation of cell proliferation, signal transduction, single fertilization, transmembrane receptor protein tyrosine kinase signaling pathway integral to membrane, integral to plasma membrane, stress fiber ATP binding, enzyme binding, macrophage colony-stimulating factor receptor activity, protein binding, protein tyrosine kinase activity, receptor activity Human MSTN HGNC UniProtKB {GO:0048632=GO_REF:0000019, GO:0043627=GO_REF:0000019, GO:0009408=GO_REF:0000019, GO:0014850=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0005102=PMID:14517293, GO:0051384=GO_REF:0000019, GO:0014732=GO_REF:0000019, GO:0033574=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0005125=GO_REF:0000037, GO:0005737=GO_REF:0000019, GO:0007517=PMID:9843994, GO:0009629=GO_REF:0000019, GO:0014741=GO_REF:0000019, GO:0051602=GO_REF:0000019, GO:0022602=GO_REF:0000019, GO:0007179=GO_REF:0000019, GO:0043403=GO_REF:0000019, GO:0045893=PMID:14517293, GO:0008083=GO_REF:0000037, GO:0008201=GO_REF:0000037} O14793 Growth/differentiation factor 8 protein 20061026 {GO:0048632=IEA, GO:0043627=IEA, GO:0009408=IEA, GO:0014850=IEA, GO:0045471=IEA, GO:0005102=IPI, GO:0051384=IEA, GO:0014732=IEA, GO:0033574=IEA, GO:0005615=IEA, GO:0005125=IEA, GO:0005737=IEA, GO:0007517=TAS, GO:0009629=IEA, GO:0014741=IEA, GO:0051602=IEA, GO:0022602=IEA, GO:0007179=IEA, GO:0043403=IEA, GO:0045893=IDA, GO:0008083=IEA, GO:0008201=IEA} muscle organ development, negative regulation of muscle hypertrophy, negative regulation of skeletal muscle tissue growth, ovulation cycle process, positive regulation of transcription, DNA-dependent, response to electrical stimulus, response to estrogen stimulus, response to ethanol, response to glucocorticoid stimulus, response to gravity, response to heat, response to muscle activity, response to testosterone stimulus, skeletal muscle atrophy, skeletal muscle tissue regeneration, transforming growth factor beta receptor signaling pathway cytoplasm, extracellular space cytokine activity, growth factor activity, heparin binding, receptor binding contributes_to Human UniProtKB:P36896 MSTO1 LIFEdb UniProtKB {GO:0048311=PMID:17349998, GO:0003674=GO_REF:0000015, GO:0043234=GO_REF:0000002, GO:0005737=GO_REF:0000054, GO:0051258=GO_REF:0000002, GO:0005741=PMID:17349998, GO:0007005=PMID:17349998} Q9BUK6 Protein misato homolog 1 protein 20100607 {GO:0048311=IMP, GO:0003674=ND, GO:0043234=IEA, GO:0005737=IDA, GO:0051258=IEA, GO:0005741=IDA, GO:0007005=IMP} mitochondrion distribution, mitochondrion organization, protein polymerization cytoplasm, mitochondrial outer membrane, protein complex molecular_function Human MSX1 BHF-UCL UniProtKB {GO:0034504=PMID:15705871, GO:0030308=PMID:15705871, GO:0008285=GO_REF:0000019, GO:0030262=PMID:15705871, GO:0010463=GO_REF:0000019, GO:0042481=GO_REF:0000019, GO:0000982=GO_REF:0000019, GO:0005634=PMID:15705871, GO:2000678=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0002039=PMID:15705871, GO:0030513=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0042475=PMID:11369996, GO:0060021=GO_REF:0000019, GO:0042474=GO_REF:0000019, GO:0051154=GO_REF:0000019, GO:0061312=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0043065=PMID:15705871, GO:0003198=GO_REF:0000019, GO:0023019=GO_REF:0000019, GO:0061180=GO_REF:0000019, GO:0050821=PMID:15705871, GO:0000122=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0035880=PMID:11369996, GO:0043565=GO_REF:0000019, GO:0048863=GO_REF:0000019, GO:0000902=PMID:15705871, GO:0007517=GO_REF:0000019, GO:0060325=PMID:12651933, GO:0060349=GO_REF:0000019, GO:0043517=PMID:15705871, GO:0035116=GO_REF:0000019, GO:0030901=GO_REF:0000019, GO:0030900=GO_REF:0000019, GO:0035115=GO_REF:0000019, GO:0060536=GO_REF:0000019} P28360 Homeobox protein MSX-1 protein 20110707 {GO:0034504=IDA, GO:0030308=IDA, GO:0008285=IEA, GO:0030262=IDA, GO:0010463=IEA, GO:0042481=IEA, GO:0000982=IEA, GO:0005634=IDA, GO:2000678=IEA, GO:0009952=IEA, GO:0002039=IPI, GO:0030513=IEA, GO:0045944=IEA, GO:0042475=IMP, GO:0060021=IEA, GO:0042474=IEA, GO:0051154=IEA, GO:0061312=IEA, GO:0005667=IEA, GO:0043066=IEA, GO:0043065=IDA, GO:0003198=IEA, GO:0023019=IEA, GO:0061180=IEA, GO:0050821=IDA, GO:0000122=IEA, GO:0001701=IEA, GO:0035880=IMP, GO:0043565=IEA, GO:0048863=IEA, GO:0000902=IDA, GO:0007517=IEA, GO:0060325=IMP, GO:0060349=IEA, GO:0043517=IC, GO:0035116=IEA, GO:0030901=IEA, GO:0030900=IEA, GO:0035115=IEA, GO:0060536=IEA} BMP signaling pathway involved in heart development, anterior/posterior pattern specification, apoptotic nuclear changes, bone morphogenesis, cartilage morphogenesis, cell morphogenesis, embryonic forelimb morphogenesis, embryonic hindlimb morphogenesis, embryonic nail plate morphogenesis, epithelial to mesenchymal transition involved in endocardial cushion formation, face morphogenesis, forebrain development, in utero embryonic development, mammary gland epithelium development, mesenchymal cell proliferation, midbrain development, middle ear morphogenesis, muscle organ development, negative regulation of apoptotic process, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of striated muscle cell differentiation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription regulatory region DNA binding, odontogenesis of dentin-containing tooth, palate development, positive regulation of BMP signaling pathway, positive regulation of DNA damage response, signal transduction by p53 class mediator, positive regulation of apoptotic process, positive regulation of transcription from RNA polymerase II promoter, protein localization to nucleus, protein stabilization, regulation of odontogenesis, signal transduction involved in regulation of gene expression, stem cell differentiation nucleus, transcription factor complex RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, p53 binding, sequence-specific DNA binding Human MSX2 HPA UniProtKB {GO:0005515=PMID:12145306, GO:0008285=GO_REF:0000019, GO:0003416=GO_REF:0000019, GO:0035313=GO_REF:0000019, GO:0044212=GO_REF:0000024, GO:0042640=GO_REF:0000019, GO:0045599=GO_REF:0000019, GO:0000982=GO_REF:0000019, GO:0032792=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:2000678=GO_REF:0000024, GO:0009952=GO_REF:0000019, GO:0045617=GO_REF:0000019, GO:0030513=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0002063=GO_REF:0000019, GO:0071392=GO_REF:0000019, GO:0061312=GO_REF:0000019, GO:0003712=GO_REF:0000024, GO:0005667=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0003198=GO_REF:0000019, GO:0023019=GO_REF:0000019, GO:0070166=GO_REF:0000019, GO:0000122=GO_REF:0000024, GO:0000978=GO_REF:0000019, GO:0001649=GO_REF:0000024, GO:0035880=GO_REF:0000019, GO:0043565=PMID:9073066, GO:0048863=GO_REF:0000019, GO:0045669=GO_REF:0000019, GO:0060364=GO_REF:0000019, GO:0060363=PMID:8968743, GO:0060346=GO_REF:0000019, GO:0071363=GO_REF:0000019, GO:0002076=GO_REF:0000019, GO:0003148=GO_REF:0000019, GO:0035116=GO_REF:0000019, GO:0035115=GO_REF:0000019, GO:0045892=GO_REF:0000024, GO:0060444=GO_REF:0000019, GO:0051795=GO_REF:0000019} P35548 Homeobox protein MSX-2 protein 20080818 {GO:0005515=IPI, GO:0008285=IEA, GO:0003416=IEA, GO:0035313=IEA, GO:0044212=ISS, GO:0042640=IEA, GO:0045599=IEA, GO:0000982=IEA, GO:0032792=IEA, GO:0005634=IDA, GO:2000678=ISS, GO:0009952=IEA, GO:0045617=IEA, GO:0030513=IEA, GO:0005737=IDA, GO:0002063=IEA, GO:0071392=IEA, GO:0061312=IEA, GO:0003712=ISS, GO:0005667=IEA, GO:0043066=IEA, GO:0043065=IEA, GO:0003198=IEA, GO:0023019=IEA, GO:0070166=IEA, GO:0000122=ISS, GO:0000978=IEA, GO:0001649=ISS, GO:0035880=IEA, GO:0043565=IDA, GO:0048863=IEA, GO:0045669=IEA, GO:0060364=IEA, GO:0060363=TAS, GO:0060346=IEA, GO:0071363=IEA, GO:0002076=IEA, GO:0003148=IEA, GO:0035116=IEA, GO:0035115=IEA, GO:0045892=ISS, GO:0060444=IEA, GO:0051795=IEA} BMP signaling pathway involved in heart development, anagen, anterior/posterior pattern specification, bone trabecula formation, branching involved in mammary gland duct morphogenesis, cellular response to estradiol stimulus, cellular response to growth factor stimulus, chondrocyte development, cranial suture morphogenesis, embryonic forelimb morphogenesis, embryonic hindlimb morphogenesis, embryonic nail plate morphogenesis, enamel mineralization, endochondral bone growth, epithelial to mesenchymal transition involved in endocardial cushion formation, frontal suture morphogenesis, negative regulation of CREB transcription factor activity, negative regulation of apoptotic process, negative regulation of cell proliferation, negative regulation of fat cell differentiation, negative regulation of keratinocyte differentiation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription regulatory region DNA binding, negative regulation of transcription, DNA-dependent, osteoblast development, osteoblast differentiation, outflow tract septum morphogenesis, positive regulation of BMP signaling pathway, positive regulation of apoptotic process, positive regulation of catagen, positive regulation of osteoblast differentiation, signal transduction involved in regulation of gene expression, stem cell differentiation, wound healing, spreading of epidermal cells cytoplasm, nucleus, transcription factor complex RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, protein binding, sequence-specific DNA binding, transcription cofactor activity, transcription regulatory region DNA binding Human MT-ATP6 GOC UniProtKB {GO:0022904=Reactome:REACT_6305, GO:0015986=GO_REF:0000029, GO:0006200=PMID:12110673, GO:0042776=Reactome:REACT_6759, GO:0015078=GO_REF:0000002, GO:0022857=PMID:12110673, GO:0005743=Reactome:REACT_1985, GO:0000276=GO_REF:0000029, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0016887=PMID:12110673, GO:0005753=PMID:12110673} P00846 ATP synthase subunit a protein 20130413 {GO:0022904=TAS, GO:0015986=NAS, GO:0006200=IDA, GO:0042776=TAS, GO:0015078=IEA, GO:0022857=IC, GO:0005743=TAS, GO:0000276=NAS, GO:0044281=TAS, GO:0016021=IEA, GO:0016887=IDA, GO:0005753=IDA} ATP catabolic process, ATP synthesis coupled proton transport, mitochondrial ATP synthesis coupled proton transport, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane, mitochondrial proton-transporting ATP synthase complex, mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ATPase activity, hydrogen ion transmembrane transporter activity, transmembrane transporter activity Human MT-ATP8 GOC UniProtKB {GO:0022904=Reactome:REACT_6305, GO:0015986=GO_REF:0000029, GO:0006200=PMID:12110673, GO:0042776=Reactome:REACT_6759, GO:0015078=GO_REF:0000002, GO:0022857=PMID:12110673, GO:0005743=Reactome:REACT_1985, GO:0000276=GO_REF:0000029, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0016887=PMID:12110673, GO:0005753=PMID:12110673} P03928 ATP synthase protein 8 protein 20130413 {GO:0022904=TAS, GO:0015986=NAS, GO:0006200=IDA, GO:0042776=TAS, GO:0015078=IEA, GO:0022857=IC, GO:0005743=TAS, GO:0000276=NAS, GO:0044281=TAS, GO:0016021=IEA, GO:0016887=IDA, GO:0005753=IDA} ATP catabolic process, ATP synthesis coupled proton transport, mitochondrial ATP synthesis coupled proton transport, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane, mitochondrial proton-transporting ATP synthase complex, mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) ATPase activity, hydrogen ion transmembrane transporter activity, transmembrane transporter activity Human MT-CO1 HGNC UniProtKB {GO:0005515=PMID:12762840, GO:0022904=Reactome:REACT_22393, GO:0009060=GO_REF:0000002, GO:0005506=GO_REF:0000002, GO:0006123=GO_REF:0000029, GO:0004129=GO_REF:0000029, GO:0070469=GO_REF:0000037, GO:0005743=Reactome:REACT_6149, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0020037=GO_REF:0000002} P00395 Cytochrome c oxidase subunit 1 protein 20061114 {GO:0005515=IPI, GO:0022904=TAS, GO:0009060=IEA, GO:0005506=IEA, GO:0006123=NAS, GO:0004129=NAS, GO:0070469=IEA, GO:0005743=TAS, GO:0009055=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0020037=IEA} aerobic respiration, mitochondrial electron transport, cytochrome c to oxygen, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane, respiratory chain cytochrome-c oxidase activity, electron carrier activity, heme binding, iron ion binding, protein binding Human UniProtKB:Q66K74 MT-CO2 Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005739=PMID:22802641, GO:0006123=PMID:2550900, GO:0005507=GO_REF:0000002, GO:0004129=PMID:2550900, GO:0070469=GO_REF:0000037, GO:0005743=Reactome:REACT_6149, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037} P00403 Cytochrome c oxidase subunit 2 protein 20130213 {GO:0022904=TAS, GO:0005739=IDA, GO:0006123=NAS, GO:0005507=IEA, GO:0004129=NAS, GO:0070469=IEA, GO:0005743=TAS, GO:0044281=TAS, GO:0016021=IEA} mitochondrial electron transport, cytochrome c to oxygen, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane, mitochondrion, respiratory chain copper ion binding, cytochrome-c oxidase activity Human MT-CO3 Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0019646=GO_REF:0000002, GO:0006123=GO_REF:0000029, GO:0004129=GO_REF:0000029, GO:0005743=Reactome:REACT_6149, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037} P00414 Cytochrome c oxidase subunit 3 protein 20130213 {GO:0022904=TAS, GO:0019646=IEA, GO:0006123=NAS, GO:0004129=NAS, GO:0005743=TAS, GO:0044281=TAS, GO:0016021=IEA} aerobic electron transport chain, mitochondrial electron transport, cytochrome c to oxygen, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane cytochrome-c oxidase activity Human MT-CYB Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0008121=PMID:6100559, GO:0006122=PMID:6100559, GO:0005743=Reactome:REACT_6300, GO:0009055=GO_REF:0000002, GO:0005750=PMID:6100559, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0046872=GO_REF:0000037} P00156 Cytochrome b protein 20130213 {GO:0022904=TAS, GO:0008121=NAS, GO:0006122=NAS, GO:0005743=TAS, GO:0009055=IEA, GO:0005750=NAS, GO:0044281=TAS, GO:0016021=IEA, GO:0046872=IEA} mitochondrial electron transport, ubiquinol to cytochrome c, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane, mitochondrial respiratory chain complex III electron carrier activity, metal ion binding, ubiquinol-cytochrome-c reductase activity Human MT-ND1 Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005515=PMID:12762840, GO:0031966=PMID:17209039, GO:0005747=PMID:12611891, GO:0005743=Reactome:REACT_6310, GO:0006120=PMID:3921850, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0008137=PMID:3921850} P03886 NADH-ubiquinone oxidoreductase chain 1 protein 20130213 {GO:0022904=TAS, GO:0005515=IPI, GO:0031966=IDA, GO:0005747=IDA, GO:0005743=TAS, GO:0006120=NAS, GO:0044281=TAS, GO:0016021=IEA, GO:0008137=NAS} mitochondrial electron transport, NADH to ubiquinone, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane, mitochondrial membrane, mitochondrial respiratory chain complex I NADH dehydrogenase (ubiquinone) activity, protein binding Human MT-ND2 Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005747=PMID:12611891, GO:0005743=Reactome:REACT_6310, GO:0006120=PMID:9475751, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0008137=PMID:3921850} P03891 NADH-ubiquinone oxidoreductase chain 2 protein 20130213 {GO:0022904=TAS, GO:0005747=IDA, GO:0005743=TAS, GO:0006120=NAS, GO:0044281=TAS, GO:0016021=IEA, GO:0008137=NAS} mitochondrial electron transport, NADH to ubiquinone, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane, mitochondrial respiratory chain complex I NADH dehydrogenase (ubiquinone) activity Human MT-ND3 IntAct UniProtKB {GO:0005515=PMID:16384638, GO:0022904=Reactome:REACT_22393, GO:0005747=PMID:12611891, GO:0005743=Reactome:REACT_6310, GO:0006120=PMID:3921850, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0008137=PMID:3921850} P03897 NADH-ubiquinone oxidoreductase chain 3 protein 20130415 {GO:0005515=IPI, GO:0022904=TAS, GO:0005747=IDA, GO:0005743=TAS, GO:0006120=NAS, GO:0044281=TAS, GO:0016021=IEA, GO:0008137=NAS} mitochondrial electron transport, NADH to ubiquinone, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane, mitochondrial respiratory chain complex I NADH dehydrogenase (ubiquinone) activity, protein binding Human UniProtKB:P05067:PRO_0000000092 MT-ND4 Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005747=PMID:12611891, GO:0005743=Reactome:REACT_6310, GO:0006120=PMID:3921850, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0008137=PMID:3921850} P03905 NADH-ubiquinone oxidoreductase chain 4 protein 20130213 {GO:0022904=TAS, GO:0005747=IDA, GO:0005743=TAS, GO:0006120=NAS, GO:0044281=TAS, GO:0016021=IEA, GO:0008137=NAS} mitochondrial electron transport, NADH to ubiquinone, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane, mitochondrial respiratory chain complex I NADH dehydrogenase (ubiquinone) activity Human MT-ND5 Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005747=PMID:12611891, GO:0005743=Reactome:REACT_6310, GO:0006120=PMID:3921850, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0008137=PMID:3921850} P03915 NADH-ubiquinone oxidoreductase chain 5 protein 20130213 {GO:0022904=TAS, GO:0005747=IDA, GO:0005743=TAS, GO:0006120=NAS, GO:0044281=TAS, GO:0016021=IEA, GO:0008137=NAS} mitochondrial electron transport, NADH to ubiquinone, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane, mitochondrial respiratory chain complex I NADH dehydrogenase (ubiquinone) activity Human MT-ND6 Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005747=GO_REF:0000029, GO:0005743=Reactome:REACT_6310, GO:0006120=GO_REF:0000029, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0008137=GO_REF:0000029} P03923 NADH-ubiquinone oxidoreductase chain 6 protein 20130213 {GO:0022904=TAS, GO:0005747=NAS, GO:0005743=TAS, GO:0006120=NAS, GO:0044281=TAS, GO:0016021=IEA, GO:0008137=NAS} mitochondrial electron transport, NADH to ubiquinone, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane, mitochondrial respiratory chain complex I NADH dehydrogenase (ubiquinone) activity Human MT1A UniProtKB UniProtKB {GO:0071294=PMID:11168427, GO:0048471=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0005507=GO_REF:0000029, GO:0005634=GO_REF:0000024, GO:0008270=GO_REF:0000024, GO:0071276=PMID:16827180, GO:0046870=GO_REF:0000029, GO:0045926=GO_REF:0000024} P04731 Metallothionein-1A protein 20111011 {GO:0071294=IEP, GO:0048471=ISS, GO:0005737=ISS, GO:0005507=NAS, GO:0005634=ISS, GO:0008270=ISS, GO:0071276=IEP, GO:0046870=NAS, GO:0045926=ISS} cellular response to cadmium ion, cellular response to zinc ion, negative regulation of growth cytoplasm, nucleus, perinuclear region of cytoplasm cadmium ion binding, copper ion binding, zinc ion binding Human UniProtKB:P13640 MT1E UniProtKB UniProtKB {GO:0071294=PMID:11168427, GO:0048471=GO_REF:0000024, GO:0005507=GO_REF:0000029, GO:0008270=GO_REF:0000024, GO:0071276=PMID:16827180, GO:0046870=GO_REF:0000029, GO:0045926=GO_REF:0000024, GO:0046872=GO_REF:0000038} P04732 Metallothionein-1E protein 20111011 {GO:0071294=IEP, GO:0048471=ISS, GO:0005507=NAS, GO:0008270=ISS, GO:0071276=IEP, GO:0046870=NAS, GO:0045926=ISS, GO:0046872=IEA} cellular response to cadmium ion, cellular response to zinc ion, negative regulation of growth perinuclear region of cytoplasm cadmium ion binding, copper ion binding, metal ion binding, zinc ion binding Human UniProtKB:P13640 MT1F UniProtKB UniProtKB {GO:0071294=GO_REF:0000024, GO:0048471=GO_REF:0000024, GO:0005507=GO_REF:0000029, GO:0008270=GO_REF:0000024, GO:0071276=PMID:16827180, GO:0046870=GO_REF:0000029, GO:0045926=GO_REF:0000024, GO:0046872=GO_REF:0000038} P04733 Metallothionein-1F protein 20120322 {GO:0071294=ISS, GO:0048471=ISS, GO:0005507=NAS, GO:0008270=ISS, GO:0071276=IEP, GO:0046870=NAS, GO:0045926=ISS, GO:0046872=IEA} cellular response to cadmium ion, cellular response to zinc ion, negative regulation of growth perinuclear region of cytoplasm cadmium ion binding, copper ion binding, metal ion binding, zinc ion binding Human UniProtKB:P13640 MT1G IntAct UniProtKB {GO:0071294=PMID:11168427, GO:0005515=PMID:12970870, GO:0071280=PMID:3403543, GO:0035924=PMID:15735762, GO:0048471=PMID:15735762, GO:0005634=PMID:15735762, GO:0046872=GO_REF:0000038, GO:0005737=PMID:3403543, GO:0042117=PMID:8119276, GO:0008270=PMID:8119276, GO:0030224=PMID:8119276, GO:0071276=PMID:16827180, GO:0045926=PMID:18332874} P13640 Metallothionein-1G protein 20130415 {GO:0071294=IEP, GO:0005515=IPI, GO:0071280=IEP, GO:0035924=IEP, GO:0048471=IDA, GO:0005634=IDA, GO:0046872=IEA, GO:0005737=IDA, GO:0042117=NAS, GO:0008270=IDA, GO:0030224=NAS, GO:0071276=IEP, GO:0045926=IDA} cellular response to cadmium ion, cellular response to copper ion, cellular response to vascular endothelial growth factor stimulus, cellular response to zinc ion, monocyte activation, monocyte differentiation, negative regulation of growth cytoplasm, nucleus, perinuclear region of cytoplasm metal ion binding, protein binding, zinc ion binding Human UniProtKB:P58062 MT1H IntAct UniProtKB {GO:0071294=PMID:11168427, GO:0005515=PMID:12970870, GO:0005737=GO_REF:0000024, GO:0048471=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0008270=GO_REF:0000024, GO:0071276=PMID:16827180, GO:0045926=GO_REF:0000024, GO:0046872=GO_REF:0000038} P80294 Metallothionein-1H protein 20130415 {GO:0071294=IEP, GO:0005515=IPI, GO:0005737=ISS, GO:0048471=ISS, GO:0005634=ISS, GO:0008270=ISS, GO:0071276=IEP, GO:0045926=ISS, GO:0046872=IEA} cellular response to cadmium ion, cellular response to zinc ion, negative regulation of growth cytoplasm, nucleus, perinuclear region of cytoplasm metal ion binding, protein binding, zinc ion binding Human UniProtKB:P58062 MT1M UniProtKB UniProtKB {GO:0071294=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0048471=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0008270=GO_REF:0000024, GO:0045926=GO_REF:0000024, GO:0046872=GO_REF:0000038} Q8N339 Metallothionein-1M protein 20120322 {GO:0071294=ISS, GO:0005737=ISS, GO:0048471=ISS, GO:0005634=ISS, GO:0008270=ISS, GO:0045926=ISS, GO:0046872=IEA} cellular response to zinc ion, negative regulation of growth cytoplasm, nucleus, perinuclear region of cytoplasm metal ion binding, zinc ion binding Human UniProtKB:P13640 MT1X PINC UniProtKB {GO:0071294=PMID:11168427, GO:0048471=GO_REF:0000024, GO:0010038=PMID:9074634, GO:0008270=GO_REF:0000024, GO:0071276=PMID:16827180, GO:0045926=GO_REF:0000024, GO:0046872=PMID:9074634, GO:0036018=PMID:11168427} P80297 Metallothionein-1X protein 20031119 {GO:0071294=IEP, GO:0048471=ISS, GO:0010038=TAS, GO:0008270=ISS, GO:0071276=IEP, GO:0045926=ISS, GO:0046872=TAS, GO:0036018=IEP} cellular response to cadmium ion, cellular response to erythropoietin, cellular response to zinc ion, negative regulation of growth, response to metal ion perinuclear region of cytoplasm metal ion binding, zinc ion binding Human MT2A IntAct UniProtKB {GO:0005515=PMID:15541360, GO:0071294=PMID:11168427, GO:0048471=GO_REF:0000024, GO:0019221=Reactome:REACT_25229, GO:0005634=GO_REF:0000024, GO:0036016=PMID:11168427, GO:0046872=GO_REF:0000038, GO:0036018=PMID:11168427, GO:0005829=Reactome:REACT_25082, GO:0005737=GO_REF:0000024, GO:0006878=PMID:6719135, GO:0008270=PMID:19536566, GO:0045926=GO_REF:0000024, GO:0060333=Reactome:REACT_25078} P02795 Metallothionein-2 protein 20130415 {GO:0005515=IPI, GO:0071294=IEP, GO:0048471=ISS, GO:0019221=TAS, GO:0005634=ISS, GO:0036016=IEP, GO:0046872=IEA, GO:0036018=IEP, GO:0005829=TAS, GO:0005737=ISS, GO:0006878=TAS, GO:0008270=IDA, GO:0045926=ISS, GO:0060333=TAS} cellular copper ion homeostasis, cellular response to erythropoietin, cellular response to interleukin-3, cellular response to zinc ion, cytokine-mediated signaling pathway, interferon-gamma-mediated signaling pathway, negative regulation of growth cytoplasm, cytosol, nucleus, perinuclear region of cytoplasm metal ion binding, protein binding, zinc ion binding Human UniProtKB:Q8TE69 MT3 PINC UniProtKB {GO:0005515=PMID:21320589, GO:0030308=PMID:18157556, GO:0006707=GO_REF:0000024, GO:0048471=PMID:20039155, GO:0071732=PMID:18157556, GO:0008283=PMID:1873033, GO:0044242=GO_REF:0000024, GO:0006882=GO_REF:0000024, GO:0060049=GO_REF:0000024, GO:0046870=PMID:18157556, GO:0032095=GO_REF:0000024, GO:0055073=PMID:18157556, GO:0046872=GO_REF:0000038, GO:0005622=PMID:21818286, GO:0043524=GO_REF:0000024, GO:0055069=PMID:18157556, GO:0030517=PMID:17712581, GO:0019430=PMID:12383939, GO:0060547=GO_REF:0000024, GO:0070374=GO_REF:0000024, GO:0070371=PMID:18554677, GO:0043154=PMID:16387743, GO:0010942=GO_REF:0000024, GO:0001666=PMID:12763630, GO:0016209=PMID:12383939, GO:0016234=PMID:20039155, GO:0005507=PMID:21320589, GO:0097214=GO_REF:0000024, GO:0016570=PMID:21818286, GO:0006875=PMID:21818286, GO:0043085=GO_REF:0000024, GO:0008021=GO_REF:0000024, GO:0010628=GO_REF:0000024, GO:0006112=GO_REF:0000024, GO:0014002=GO_REF:0000024, GO:0010507=GO_REF:0000024, GO:0043491=PMID:18554677, GO:0033210=GO_REF:0000024, GO:0008270=PMID:21320589, GO:0006829=GO_REF:0000024, GO:2000376=GO_REF:0000024, GO:0034599=PMID:20039155, GO:0045893=GO_REF:0000024, GO:0045892=GO_REF:0000024} P25713 Metallothionein-3 protein 20030904 {GO:0005515=IPI, GO:0030308=TAS, GO:0006707=ISS, GO:0048471=IDA, GO:0071732=IDA, GO:0008283=TAS, GO:0044242=ISS, GO:0006882=ISS, GO:0060049=ISS, GO:0046870=IDA, GO:0032095=ISS, GO:0055073=IDA, GO:0046872=IEA, GO:0005622=IDA, GO:0043524=ISS, GO:0055069=IDA, GO:0030517=IDA, GO:0019430=IDA, GO:0060547=ISS, GO:0070374=ISS, GO:0070371=IDA, GO:0043154=IDA, GO:0010942=ISS, GO:0001666=IDA, GO:0016209=NAS, GO:0016234=IDA, GO:0005507=IDA, GO:0097214=ISS, GO:0016570=IMP, GO:0006875=TAS, GO:0043085=ISS, GO:0008021=ISS, GO:0010628=ISS, GO:0006112=ISS, GO:0014002=ISS, GO:0010507=ISS, GO:0043491=IDA, GO:0033210=ISS, GO:0008270=IDA, GO:0006829=ISS, GO:2000376=ISS, GO:0034599=IEP, GO:0045893=ISS, GO:0045892=ISS} ERK1 and ERK2 cascade, astrocyte development, cadmium ion homeostasis, cell proliferation, cellular lipid catabolic process, cellular metal ion homeostasis, cellular response to nitric oxide, cellular response to oxidative stress, cellular zinc ion homeostasis, cholesterol catabolic process, energy reserve metabolic process, histone modification, leptin-mediated signaling pathway, negative regulation of autophagy, negative regulation of axon extension, negative regulation of cell growth, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of necrotic cell death, negative regulation of neuron apoptotic process, negative regulation of transcription, DNA-dependent, positive regulation of ERK1 and ERK2 cascade, positive regulation of catalytic activity, positive regulation of cell death, positive regulation of gene expression, positive regulation of lysosomal membrane permeability, positive regulation of oxygen metabolic process, positive regulation of transcription, DNA-dependent, protein kinase B signaling cascade, regulation of protein glycosylation, regulation of response to food, removal of superoxide radicals, response to hypoxia, zinc ion homeostasis, zinc ion transport inclusion body, intracellular, perinuclear region of cytoplasm, synaptic vesicle antioxidant activity, cadmium ion binding, copper ion binding, metal ion binding, protein binding, zinc ion binding Human MTA1 HPA UniProtKB {GO:0001103=PMID:22926524, GO:0003700=GO_REF:0000002, GO:0005783=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000002, GO:0043231=GO_REF:0000052, GO:0043565=GO_REF:0000002, GO:0007165=PMID:8083195, GO:0005737=GO_REF:0000052, GO:0016581=GO_REF:0000019, GO:0003682=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0019899=GO_REF:0000019, GO:0033363=GO_REF:0000019} Q13330 Metastasis-associated protein MTA1 protein 20101115 {GO:0001103=IPI, GO:0003700=IEA, GO:0005783=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0043231=IDA, GO:0043565=IEA, GO:0007165=TAS, GO:0005737=IDA, GO:0016581=IEA, GO:0003682=IEA, GO:0008270=IEA, GO:0019899=IEA, GO:0033363=IEA} secretory granule organization, signal transduction NuRD complex, cytoplasm, endoplasmic reticulum, intracellular membrane-bounded organelle, nucleolus, nucleus DNA binding, RNA polymerase II repressing transcription factor binding, chromatin binding, enzyme binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human MTA2 HPA UniProtKB {GO:0001103=PMID:22926524, GO:0005515=PMID:20127688, GO:0005667=PMID:15920471, GO:0003700=GO_REF:0000002, GO:0044212=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000122=GO_REF:0000019, GO:0000989=GO_REF:0000019, GO:0006333=PMID:10444591, GO:0043565=GO_REF:0000002, GO:0006306=GO_REF:0000019, GO:0000118=PMID:10444591, GO:0016581=PMID:19644445, GO:0003682=GO_REF:0000002, GO:0045944=GO_REF:0000019, GO:0001085=PMID:15920471, GO:0008270=GO_REF:0000002, GO:0004407=GO_REF:0000019} O94776 Metastasis-associated protein MTA2 protein 20080205 {GO:0001103=IPI, GO:0005515=IPI, GO:0005667=IDA, GO:0003700=IEA, GO:0044212=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0000122=IEA, GO:0000989=IEA, GO:0006333=TAS, GO:0043565=IEA, GO:0006306=IEA, GO:0000118=TAS, GO:0016581=IDA, GO:0003682=IEA, GO:0045944=IEA, GO:0001085=IPI, GO:0008270=IEA, GO:0004407=IEA} DNA methylation, chromatin assembly or disassembly, negative regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter NuRD complex, histone deacetylase complex, nucleolus, nucleus, transcription factor complex RNA polymerase II repressing transcription factor binding, RNA polymerase II transcription factor binding, chromatin binding, histone deacetylase activity, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding transcription factor activity, transcription regulatory region DNA binding, zinc ion binding NOT Human MTA3 HPA UniProtKB {GO:0008284=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000002, GO:0043231=GO_REF:0000052, GO:0043565=GO_REF:0000002, GO:0005737=GO_REF:0000019, GO:0008278=GO_REF:0000019, GO:0010971=GO_REF:0000019, GO:0016581=GO_REF:0000019, GO:0003682=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q9BTC8 Metastasis-associated protein MTA3 protein 20110516 {GO:0008284=IEA, GO:0003700=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0043231=IDA, GO:0043565=IEA, GO:0005737=IEA, GO:0008278=IEA, GO:0010971=IEA, GO:0016581=IEA, GO:0003682=IEA, GO:0008270=IEA} positive regulation of G2/M transition of mitotic cell cycle, positive regulation of cell proliferation NuRD complex, cohesin complex, cytoplasm, intracellular membrane-bounded organelle, nucleolus, nucleus DNA binding, chromatin binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human MTAP Reactome UniProtKB {GO:0004731=GO_REF:0000003, GO:0005634=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0006738=PMID:19001417, GO:0004645=GO_REF:0000002, GO:0003824=GO_REF:0000002, GO:0033574=GO_REF:0000019, GO:0005829=Reactome:REACT_75786, GO:0034641=Reactome:REACT_13, GO:0006166=GO_REF:0000037, GO:0017061=Reactome:REACT_75786, GO:0005737=GO_REF:0000040, GO:0006139=PMID:8687427, GO:0000096=Reactome:REACT_115639, GO:0019509=Reactome:REACT_75881, GO:0006595=Reactome:REACT_14820, GO:0009116=GO_REF:0000002} Q13126 S-methyl-5'-thioadenosine phosphorylase protein 20110330 {GO:0004731=IEA, GO:0005634=IEA, GO:0044281=TAS, GO:0006738=IDA, GO:0004645=IEA, GO:0003824=IEA, GO:0033574=IEA, GO:0005829=TAS, GO:0034641=TAS, GO:0006166=IEA, GO:0017061=TAS, GO:0005737=IEA, GO:0006139=TAS, GO:0000096=TAS, GO:0019509=TAS, GO:0006595=TAS, GO:0009116=IEA} L-methionine salvage from methylthioadenosine, cellular nitrogen compound metabolic process, nicotinamide riboside catabolic process, nucleobase-containing compound metabolic process, nucleoside metabolic process, polyamine metabolic process, purine ribonucleoside salvage, response to testosterone stimulus, small molecule metabolic process, sulfur amino acid metabolic process cytoplasm, cytosol, nucleus S-methyl-5-thioadenosine phosphorylase activity, catalytic activity, phosphorylase activity, purine-nucleoside phosphorylase activity Human MTBP ENSEMBL UniProtKB {GO:0008285=GO_REF:0000019, GO:0007050=GO_REF:0000037, GO:0007089=GO_REF:0000019} Q96DY7 Mdm2-binding protein protein 20130413 {GO:0008285=IEA, GO:0007050=IEA, GO:0007089=IEA} cell cycle arrest, negative regulation of cell proliferation, traversing start control point of mitotic cell cycle Human Ensembl:ENSMUSP00000022998 MTCH1 UniProtKB UniProtKB {GO:0005739=PMID:12377771, GO:0005515=PMID:10551805, GO:0005622=PMID:10551805, GO:0043065=PMID:12377771, GO:0006919=PMID:12377771, GO:0045161=PMID:10551805, GO:0005743=GO_REF:0000039, GO:0006810=GO_REF:0000037, GO:0009966=PMID:10551805, GO:0016021=GO_REF:0000037} Q9NZJ7 Mitochondrial carrier homolog 1 protein 20061205 {GO:0005739=IMP, GO:0005515=IPI, GO:0005622=NAS, GO:0043065=IEP, GO:0006919=IMP, GO:0045161=NAS, GO:0005743=IEA, GO:0006810=IEA, GO:0009966=NAS, GO:0016021=IEA} activation of cysteine-type endopeptidase activity involved in apoptotic process, neuronal ion channel clustering, positive regulation of apoptotic process, regulation of signal transduction, transport integral to membrane, intracellular, mitochondrial inner membrane, mitochondrion protein binding Human MTCH2 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005743=GO_REF:0000039, GO:0006810=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q9Y6C9 Mitochondrial carrier homolog 2 protein 20110516 {GO:0005739=IDA, GO:0005743=IEA, GO:0006810=IEA, GO:0016021=IEA} transport integral to membrane, mitochondrial inner membrane, mitochondrion Human MTCP1 PINC UniProtKB {GO:0005739=GO_REF:0000019, GO:0008283=PMID:8361760} P56278 Protein p13 MTCP-1 protein 20030904 {GO:0005739=IEA, GO:0008283=TAS} cell proliferation mitochondrion Human MTDH HPA UniProtKB {GO:0005515=PMID:18316612, GO:0051897=PMID:17704808, GO:0048471=PMID:14980505, GO:0005783=GO_REF:0000052, GO:0005634=PMID:16452207, GO:0005737=PMID:19648967, GO:0046581=GO_REF:0000024, GO:0016324=GO_REF:0000024, GO:0051092=PMID:18316612, GO:0070830=GO_REF:0000019, GO:0001085=PMID:18316612, GO:0043123=PMID:16452207, GO:0031663=PMID:19740331, GO:0031965=GO_REF:0000039, GO:0043066=PMID:17704808, GO:0051059=PMID:16452207, GO:0003713=PMID:18316612, GO:0005730=GO_REF:0000052, GO:0000122=PMID:15927426, GO:0045766=PMID:19940250, GO:0016604=PMID:19648967, GO:0005789=GO_REF:0000024, GO:0005923=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0010508=PMID:21127263} Q86UE4 Protein LYRIC protein 20101115 {GO:0005515=IPI, GO:0051897=IDA, GO:0048471=IDA, GO:0005783=IDA, GO:0005634=IDA, GO:0005737=IDA, GO:0046581=ISS, GO:0016324=ISS, GO:0051092=IDA, GO:0070830=IEA, GO:0001085=IPI, GO:0043123=IDA, GO:0031663=IMP, GO:0031965=IEA, GO:0043066=IDA, GO:0051059=IPI, GO:0003713=IMP, GO:0005730=IDA, GO:0000122=IDA, GO:0045766=IDA, GO:0016604=IDA, GO:0005789=ISS, GO:0005923=ISS, GO:0016021=IEA, GO:0010508=IDA} lipopolysaccharide-mediated signaling pathway, negative regulation of apoptotic process, negative regulation of transcription from RNA polymerase II promoter, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of angiogenesis, positive regulation of autophagy, positive regulation of protein kinase B signaling cascade, tight junction assembly apical plasma membrane, cytoplasm, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, intercellular canaliculus, nuclear body, nuclear membrane, nucleolus, nucleus, perinuclear region of cytoplasm, tight junction NF-kappaB binding, RNA polymerase II transcription factor binding, protein binding, transcription coactivator activity Human MTERF BHF-UCL UniProtKB {GO:0042645=PMID:18063578, GO:0005515=PMID:20195357, GO:0005739=PMID:9118945, GO:0006353=PMID:20550934, GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000037, GO:0003690=PMID:20550934, GO:0005759=Reactome:REACT_2027, GO:0032392=PMID:20550934, GO:0006390=Reactome:REACT_1484, GO:0006393=Reactome:REACT_610} Q99551 Transcription termination factor, mitochondrial protein 20090218 {GO:0042645=IDA, GO:0005515=IPI, GO:0005739=TAS, GO:0006353=IDA, GO:0010467=TAS, GO:0006355=IEA, GO:0003690=IDA, GO:0005759=TAS, GO:0032392=IDA, GO:0006390=TAS, GO:0006393=TAS} DNA geometric change, DNA-dependent transcription, termination, gene expression, regulation of transcription, DNA-dependent, termination of mitochondrial transcription, transcription from mitochondrial promoter mitochondrial matrix, mitochondrial nucleoid, mitochondrion double-stranded DNA binding, protein binding Human MTERFD1 UniProtKB UniProtKB {GO:0005739=PMID:17662942, GO:0044212=PMID:17662942, GO:0045892=PMID:17662942, GO:0006351=GO_REF:0000037} Q96E29 mTERF domain-containing protein 1, mitochondrial protein 20100929 {GO:0005739=IDA, GO:0044212=IDA, GO:0045892=IMP, GO:0006351=IEA} negative regulation of transcription, DNA-dependent, transcription, DNA-dependent mitochondrion transcription regulatory region DNA binding Human MTERFD2 MGI UniProtKB {GO:0007507=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0042255=GO_REF:0000019, GO:0006364=GO_REF:0000037, GO:0006626=GO_REF:0000019, GO:0043010=GO_REF:0000019, GO:0019843=PMID:21531335, GO:0006390=GO_REF:0000019, GO:0005762=PMID:21531335} Q7Z6M4 mTERF domain-containing protein 2 protein 20111227 {GO:0007507=IEA, GO:0005739=IEA, GO:0042255=IEA, GO:0006364=IEA, GO:0006626=IEA, GO:0043010=IEA, GO:0019843=IDA, GO:0006390=IEA, GO:0005762=IDA} camera-type eye development, heart development, protein targeting to mitochondrion, rRNA processing, ribosome assembly, transcription from mitochondrial promoter mitochondrial large ribosomal subunit, mitochondrion rRNA binding Human MTF1 HPA UniProtKB {GO:0005515=PMID:19060904, GO:0035035=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0006357=PMID:3208749, GO:0003713=PMID:3208749, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0001047=PMID:15735762, GO:0000979=GO_REF:0000019, GO:0003677=PMID:8065932, GO:0006351=GO_REF:0000037, GO:0045944=GO_REF:0000019, GO:0010038=PMID:8065932, GO:0008270=GO_REF:0000002, GO:0006979=GO_REF:0000019, GO:0046686=GO_REF:0000019} Q14872 Metal regulatory transcription factor 1 protein 20111111 {GO:0005515=IPI, GO:0035035=IEA, GO:0003700=IEA, GO:0006357=TAS, GO:0003713=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0001047=IDA, GO:0000979=IEA, GO:0003677=TAS, GO:0006351=IEA, GO:0045944=IEA, GO:0010038=TAS, GO:0008270=IEA, GO:0006979=IEA, GO:0046686=IEA} positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, response to cadmium ion, response to metal ion, response to oxidative stress, transcription, DNA-dependent nucleolus, nucleus DNA binding, RNA polymerase II core promoter sequence-specific DNA binding, core promoter binding, histone acetyltransferase binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, zinc ion binding NOT Human MTF2 UniProtKB UniProtKB {GO:0048863=GO_REF:0000024, GO:0035098=GO_REF:0000024, GO:0061087=GO_REF:0000024, GO:0007379=GO_REF:0000024, GO:0045944=GO_REF:0000024, GO:0019827=GO_REF:0000024, GO:0061086=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0000122=GO_REF:0000024, GO:0035064=PMID:23142980, GO:0003677=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q9Y483 Metal-response element-binding transcription factor 2 protein 20130222 {GO:0048863=ISS, GO:0035098=ISS, GO:0061087=ISS, GO:0007379=ISS, GO:0045944=ISS, GO:0019827=ISS, GO:0061086=ISS, GO:0008270=IEA, GO:0000122=ISS, GO:0035064=IDA, GO:0003677=IEA, GO:0016568=IEA} chromatin modification, negative regulation of histone H3-K27 methylation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of histone H3-K27 methylation, positive regulation of transcription from RNA polymerase II promoter, segment specification, stem cell differentiation, stem cell maintenance ESC/E(Z) complex DNA binding, methylated histone residue binding, zinc ion binding colocalizes_with Human UniProtKB:Q02395 MTFP1 UniProtKB UniProtKB {GO:0000266=PMID:15985469, GO:0005743=PMID:15985469, GO:0006915=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q9UDX5 Mitochondrial fission process protein 1 protein 20110815 {GO:0000266=IMP, GO:0005743=IDA, GO:0006915=IEA, GO:0016021=IEA} apoptotic process, mitochondrial fission integral to membrane, mitochondrial inner membrane Human MTFR1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000024, GO:0009060=GO_REF:0000024, GO:0000266=GO_REF:0000024, GO:0005886=PMID:10942595, GO:0007005=GO_REF:0000024} Q15390 Mitochondrial fission regulator 1 protein 20120410 {GO:0005739=ISS, GO:0009060=ISS, GO:0000266=ISS, GO:0005886=IDA, GO:0007005=ISS} aerobic respiration, mitochondrial fission, mitochondrion organization mitochondrion, plasma membrane Human UniProtKB:Q9PTD5 MTG1 HPA UniProtKB {GO:0006184=GO_REF:0000033, GO:0005739=GO_REF:0000052, GO:0042254=GO_REF:0000033, GO:0003924=GO_REF:0000033, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005525=GO_REF:0000037} Q9BT17 Mitochondrial GTPase 1 protein 20110516 {GO:0006184=IBA, GO:0005739=IDA, GO:0042254=IBA, GO:0003924=IBA, GO:0005730=IDA, GO:0005634=IDA, GO:0005525=IEA} GTP catabolic process, ribosome biogenesis mitochondrion, nucleolus, nucleus GTP binding, GTPase activity Human MTHFD1 HPA UniProtKB {GO:0006767=Reactome:REACT_11238, GO:0009086=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0004329=Reactome:REACT_11109, GO:0004477=Reactome:REACT_11205, GO:0005524=GO_REF:0000037, GO:0035999=GO_REF:0000041, GO:0005829=Reactome:REACT_11205, GO:0005739=PMID:3528153, GO:0004488=GO_REF:0000033, GO:0005737=GO_REF:0000052, GO:0004486=Reactome:REACT_11192, GO:0006766=Reactome:REACT_11193, GO:0046655=Reactome:REACT_11167, GO:0009396=GO_REF:0000002, GO:0006730=GO_REF:0000033, GO:0000105=GO_REF:0000037, GO:0006164=GO_REF:0000037} P11586 C-1-tetrahydrofolate synthase, cytoplasmic protein 20080818 {GO:0006767=TAS, GO:0009086=IEA, GO:0044281=TAS, GO:0004329=TAS, GO:0004477=TAS, GO:0005524=IEA, GO:0035999=IEA, GO:0005829=TAS, GO:0005739=TAS, GO:0004488=IBA, GO:0005737=IDA, GO:0004486=TAS, GO:0006766=TAS, GO:0046655=TAS, GO:0009396=IEA, GO:0006730=IBA, GO:0000105=IEA, GO:0006164=IEA} folic acid metabolic process, folic acid-containing compound biosynthetic process, histidine biosynthetic process, methionine biosynthetic process, one-carbon metabolic process, purine nucleotide biosynthetic process, small molecule metabolic process, tetrahydrofolate interconversion, vitamin metabolic process, water-soluble vitamin metabolic process cytoplasm, cytosol, mitochondrion "ATP binding, formate-tetrahydrofolate ligase activity, methenyltetrahydrofolate cyclohydrolase activity, methylenetetrahydrofolate dehydrogenase (NADP+) activity, methylenetetrahydrofolate dehydrogenase NAD(P)+"" activity""" Human MTHFD1L BHF-UCL UniProtKB {GO:0015942=PMID:16171773, GO:0004329=PMID:12937168, GO:0004477=GO_REF:0000033, GO:0005524=PMID:16171773, GO:0042803=PMID:16171773, GO:0035999=GO_REF:0000041, GO:0005829=GO_REF:0000033, GO:0005739=PMID:12937168, GO:0004488=GO_REF:0000033, GO:0006760=PMID:12937168, GO:0046653=PMID:12937168, GO:0009396=GO_REF:0000002, GO:0006730=GO_REF:0000033} Q6UB35 Monofunctional C1-tetrahydrofolate synthase, mitochondrial protein 20090720 {GO:0015942=IDA, GO:0004329=IDA, GO:0004477=IBA, GO:0005524=IDA, GO:0042803=IDA, GO:0035999=IEA, GO:0005829=IBA, GO:0005739=IDA, GO:0004488=IBA, GO:0006760=IDA, GO:0046653=IDA, GO:0009396=IEA, GO:0006730=IBA} folic acid-containing compound biosynthetic process, folic acid-containing compound metabolic process, formate metabolic process, one-carbon metabolic process, tetrahydrofolate interconversion, tetrahydrofolate metabolic process cytosol, mitochondrion ATP binding, formate-tetrahydrofolate ligase activity, methenyltetrahydrofolate cyclohydrolase activity, methylenetetrahydrofolate dehydrogenase (NADP+) activity, protein homodimerization activity Human MTHFD2 ENSEMBL UniProtKB {GO:0000287=PMID:8218174, GO:0009408=GO_REF:0000019, GO:0004329=GO_REF:0000033, GO:0004477=PMID:8218174, GO:0005829=GO_REF:0000033, GO:0005739=GO_REF:0000019, GO:0004488=GO_REF:0000002, GO:0004487=PMID:8218174, GO:0016787=GO_REF:0000038, GO:0042301=PMID:8218174, GO:0046653=PMID:8218174, GO:0009396=GO_REF:0000002, GO:0006730=GO_REF:0000033} Q7Z650 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial protein 20130413 {GO:0000287=IDA, GO:0009408=IEA, GO:0004329=IBA, GO:0004477=ISS, GO:0005829=IBA, GO:0005739=IEA, GO:0004488=IEA, GO:0004487=IDA, GO:0016787=IEA, GO:0042301=IDA, GO:0046653=IDA, GO:0009396=IEA, GO:0006730=IBA} folic acid-containing compound biosynthetic process, one-carbon metabolic process, response to heat, tetrahydrofolate metabolic process cytosol, mitochondrion formate-tetrahydrofolate ligase activity, hydrolase activity, magnesium ion binding, methenyltetrahydrofolate cyclohydrolase activity, methylenetetrahydrofolate dehydrogenase (NAD+) activity, methylenetetrahydrofolate dehydrogenase (NADP+) activity, phosphate ion binding Human Ensembl:ENSRNOP00000014603 MTHFD2L UniPathway UniProtKB {GO:0005743=GO_REF:0000039, GO:0009086=GO_REF:0000037, GO:0004329=GO_REF:0000033, GO:0004477=GO_REF:0000033, GO:0005829=GO_REF:0000033, GO:0035999=GO_REF:0000041, GO:0005739=GO_REF:0000033, GO:0004488=GO_REF:0000033, GO:0004487=GO_REF:0000033, GO:0009396=GO_REF:0000002, GO:0006730=GO_REF:0000033, GO:0000105=GO_REF:0000037, GO:0006164=GO_REF:0000037} Q9H903 Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 protein 20130413 {GO:0005743=IEA, GO:0009086=IEA, GO:0004329=IBA, GO:0004477=IBA, GO:0005829=IBA, GO:0035999=IEA, GO:0005739=IBA, GO:0004488=IBA, GO:0004487=IBA, GO:0009396=IEA, GO:0006730=IBA, GO:0000105=IEA, GO:0006164=IEA} folic acid-containing compound biosynthetic process, histidine biosynthetic process, methionine biosynthetic process, one-carbon metabolic process, purine nucleotide biosynthetic process, tetrahydrofolate interconversion cytosol, mitochondrial inner membrane, mitochondrion formate-tetrahydrofolate ligase activity, methenyltetrahydrofolate cyclohydrolase activity, methylenetetrahydrofolate dehydrogenase (NAD+) activity, methylenetetrahydrofolate dehydrogenase (NADP+) activity Human UniPathway:UPA00193 MTHFR ENSEMBL UniProtKB {GO:0006520=PMID:7647779, GO:0008015=PMID:7647779, GO:0009086=GO_REF:0000019, GO:0006767=Reactome:REACT_11238, GO:0044281=Reactome:REACT_111217, GO:0050667=PMID:20031578, GO:0035999=GO_REF:0000041, GO:0005829=Reactome:REACT_11102, GO:0072341=PMID:20031578, GO:0004489=GO_REF:0000019, GO:0006766=Reactome:REACT_11193, GO:0046655=Reactome:REACT_11167, GO:0006555=GO_REF:0000002} Q8IU67 Methylenetetrahydrofolate reductase short isoform protein 20130413 {GO:0006520=TAS, GO:0008015=TAS, GO:0009086=IEA, GO:0006767=TAS, GO:0044281=TAS, GO:0050667=IDA, GO:0035999=IEA, GO:0005829=TAS, GO:0072341=IDA, GO:0004489=IEA, GO:0006766=TAS, GO:0046655=TAS, GO:0006555=IEA} blood circulation, cellular amino acid metabolic process, folic acid metabolic process, homocysteine metabolic process, methionine biosynthetic process, methionine metabolic process, small molecule metabolic process, tetrahydrofolate interconversion, vitamin metabolic process, water-soluble vitamin metabolic process cytosol methylenetetrahydrofolate reductase (NADPH) activity, modified amino acid binding Human Ensembl:ENSMUSP00000069774 MTHFS HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005542=GO_REF:0000037, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0030272=PMID:19738041, GO:0046653=PMID:19738041, GO:0015942=PMID:8522195, GO:0009396=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0005829=GO_REF:0000029} P49914 5-formyltetrahydrofolate cyclo-ligase protein 20101115 {GO:0005737=IDA, GO:0005542=IEA, GO:0005794=IDA, GO:0005886=IDA, GO:0030272=IDA, GO:0046653=IDA, GO:0015942=NAS, GO:0009396=IEA, GO:0005524=IEA, GO:0005829=NAS} folic acid-containing compound biosynthetic process, formate metabolic process, tetrahydrofolate metabolic process Golgi apparatus, cytoplasm, cytosol, plasma membrane 5-formyltetrahydrofolate cyclo-ligase activity, ATP binding, folic acid binding Human MTHFSD UniProtKB UniProtKB {GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0030272=GO_REF:0000002, GO:0009396=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000002} Q2M296 Methenyltetrahydrofolate synthase domain-containing protein protein 20130413 {GO:0000166=IEA, GO:0003723=IEA, GO:0030272=IEA, GO:0009396=IEA, GO:0003676=IEA, GO:0005524=IEA} folic acid-containing compound biosynthetic process 5-formyltetrahydrofolate cyclo-ligase activity, ATP binding, RNA binding, nucleic acid binding, nucleotide binding Human UniProtKB-KW:KW-0694 MTIF2 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0006446=GO_REF:0000024, GO:0003924=GO_REF:0000002, GO:0003743=GO_REF:0000037, GO:0043024=GO_REF:0000024, GO:0005525=GO_REF:0000037, GO:0008135=GO_REF:0000024} P46199 Translation initiation factor IF-2, mitochondrial protein 20080818 {GO:0005739=IDA, GO:0006446=ISS, GO:0003924=IEA, GO:0003743=IEA, GO:0043024=ISS, GO:0005525=IEA, GO:0008135=ISS} regulation of translational initiation mitochondrion GTP binding, GTPase activity, ribosomal small subunit binding, translation factor activity, nucleic acid binding, translation initiation factor activity Human MTIF3 HGNC UniProtKB {GO:0005739=PMID:12095986, GO:0006446=PMID:12095986, GO:0003743=GO_REF:0000037, GO:0043024=PMID:12095986, GO:0032790=PMID:12095986, GO:0008135=PMID:12095986} Q9H2K0 Translation initiation factor IF-3, mitochondrial protein 20070906 {GO:0005739=ISS, GO:0006446=ISS, GO:0003743=IEA, GO:0043024=ISS, GO:0032790=ISS, GO:0008135=ISS} regulation of translational initiation, ribosome disassembly mitochondrion ribosomal small subunit binding, translation factor activity, nucleic acid binding, translation initiation factor activity Human UniProtKB:Q32KZ1 MTM1 Reactome UniProtKB {GO:0044088=PMID:14722070, GO:0045109=PMID:21135508, GO:0005886=PMID:12847286, GO:0030175=PMID:12118066, GO:0044281=Reactome:REACT_111217, GO:0015031=GO_REF:0000037, GO:0046716=GO_REF:0000019, GO:0005829=Reactome:REACT_121390, GO:0005737=PMID:12118066, GO:0006470=PMID:9537414, GO:0052629=PMID:12646134, GO:0004721=PMID:9537414, GO:0004725=GO_REF:0000002, GO:0048311=PMID:21135508, GO:0006661=Reactome:REACT_121025, GO:0005770=PMID:14722070, GO:0008333=PMID:14722070, GO:0001726=PMID:12118066, GO:0019215=PMID:21135508, GO:0070584=PMID:21135508, GO:0004438=PMID:10900271, GO:0046856=PMID:12646134, GO:0035091=PMID:14722070, GO:0006644=Reactome:REACT_121175, GO:0031674=GO_REF:0000019} Q13496 Myotubularin protein 20130301 {GO:0044088=IDA, GO:0045109=IMP, GO:0005886=IDA, GO:0030175=IDA, GO:0044281=TAS, GO:0015031=IEA, GO:0046716=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0006470=IDA, GO:0052629=IDA, GO:0004721=IDA, GO:0004725=IEA, GO:0048311=IMP, GO:0006661=TAS, GO:0005770=IDA, GO:0008333=IDA, GO:0001726=IDA, GO:0019215=IDA, GO:0070584=IDA, GO:0004438=IDA, GO:0046856=IDA, GO:0035091=IDA, GO:0006644=TAS, GO:0031674=IEA} endosome to lysosome transport, intermediate filament organization, mitochondrion distribution, mitochondrion morphogenesis, muscle cell homeostasis, phosphatidylinositol biosynthetic process, phosphatidylinositol dephosphorylation, phospholipid metabolic process, protein dephosphorylation, protein transport, regulation of vacuole organization, small molecule metabolic process I band, cytoplasm, cytosol, filopodium, late endosome, plasma membrane, ruffle intermediate filament binding, phosphatidylinositol binding, phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity, phosphatidylinositol-3-phosphatase activity, phosphoprotein phosphatase activity, protein tyrosine phosphatase activity Human MTMR1 InterPro UniProtKB {GO:0016791=GO_REF:0000002, GO:0005737=GO_REF:0000024, GO:0006661=Reactome:REACT_121025, GO:0005886=GO_REF:0000024, GO:0004438=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0006644=Reactome:REACT_121175, GO:0004725=GO_REF:0000002, GO:0005829=Reactome:REACT_121287} Q8NEC6 Myotubularin-related protein 1 protein 20130413 {GO:0016791=IEA, GO:0005737=ISS, GO:0006661=TAS, GO:0005886=ISS, GO:0004438=ISS, GO:0044281=TAS, GO:0006644=TAS, GO:0004725=IEA, GO:0005829=TAS} phosphatidylinositol biosynthetic process, phospholipid metabolic process, small molecule metabolic process cytoplasm, cytosol, plasma membrane phosphatase activity, phosphatidylinositol-3-phosphatase activity, protein tyrosine phosphatase activity Human InterPro:IPR010569|InterPro:IPR017906 MTMR10 InterPro UniProtKB {GO:0016791=GO_REF:0000002} Q9NXD2 Myotubularin-related protein 10 protein 20130413 {GO:0016791=IEA} phosphatase activity Human InterPro:IPR010569|InterPro:IPR017906 MTMR11 InterPro UniProtKB {GO:0016791=GO_REF:0000002} A4FU01 Myotubularin-related protein 11 protein 20130413 {GO:0016791=IEA} phosphatase activity Human InterPro:IPR010569|InterPro:IPR017906 MTMR12 UniProtKB UniProtKB {GO:0016791=GO_REF:0000002, GO:0005737=GO_REF:0000039} Q9C0I1 Myotubularin-related protein 12 protein 20130413 {GO:0016791=IEA, GO:0005737=IEA} cytoplasm phosphatase activity Human UniProtKB-SubCell:SL-0086 MTMR14 Reactome UniProtKB {GO:0048471=PMID:17008356, GO:0006661=Reactome:REACT_121025, GO:0004438=PMID:17008356, GO:0044281=Reactome:REACT_111217, GO:0006644=Reactome:REACT_121175, GO:0001726=PMID:17008356, GO:0004725=GO_REF:0000002, GO:0005829=Reactome:REACT_121287} Q8NCE2 Myotubularin-related protein 14 protein 20130301 {GO:0048471=IDA, GO:0006661=TAS, GO:0004438=IDA, GO:0044281=TAS, GO:0006644=TAS, GO:0001726=IDA, GO:0004725=IEA, GO:0005829=TAS} phosphatidylinositol biosynthetic process, phospholipid metabolic process, small molecule metabolic process cytosol, perinuclear region of cytoplasm, ruffle phosphatidylinositol-3-phosphatase activity, protein tyrosine phosphatase activity Human MTMR2 BHF-UCL UniProtKB {GO:0005515=PMID:12837694, GO:0030424=GO_REF:0000024, GO:0005634=PMID:12837694, GO:0044281=Reactome:REACT_111217, GO:0030425=GO_REF:0000024, GO:0042803=GO_REF:0000019, GO:0005829=GO_REF:0000024, GO:0005737=PMID:12837694, GO:0006470=PMID:9736772, GO:0043197=GO_REF:0000024, GO:0048666=GO_REF:0000019, GO:0045806=GO_REF:0000024, GO:0031642=GO_REF:0000019, GO:0004725=GO_REF:0000002, GO:0005774=GO_REF:0000019, GO:0051262=GO_REF:0000019, GO:0006661=Reactome:REACT_120918, GO:2000643=GO_REF:0000024, GO:2000645=GO_REF:0000024, GO:0014069=GO_REF:0000024, GO:0032288=GO_REF:0000019, GO:0008021=GO_REF:0000024, GO:0052866=GO_REF:0000019, GO:0097062=GO_REF:0000024, GO:0090394=GO_REF:0000024, GO:0046855=GO_REF:0000019, GO:0031901=GO_REF:0000039, GO:0046856=GO_REF:0000019, GO:0097060=GO_REF:0000024, GO:0008138=PMID:9736772, GO:0006644=Reactome:REACT_121175, GO:0002091=GO_REF:0000024} Q13614 Myotubularin-related protein 2 protein 20120119 {GO:0005515=IPI, GO:0030424=ISS, GO:0005634=IDA, GO:0044281=TAS, GO:0030425=ISS, GO:0042803=IEA, GO:0005829=ISS, GO:0005737=IDA, GO:0006470=NAS, GO:0043197=ISS, GO:0048666=IEA, GO:0045806=ISS, GO:0031642=IEA, GO:0004725=IEA, GO:0005774=IEA, GO:0051262=IEA, GO:0006661=TAS, GO:2000643=ISS, GO:2000645=ISS, GO:0014069=ISS, GO:0032288=IEA, GO:0008021=ISS, GO:0052866=IEA, GO:0097062=ISS, GO:0090394=ISS, GO:0046855=IEA, GO:0031901=IEA, GO:0046856=IEA, GO:0097060=ISS, GO:0008138=NAS, GO:0006644=TAS, GO:0002091=ISS} dendritic spine maintenance, inositol phosphate dephosphorylation, myelin assembly, negative regulation of endocytosis, negative regulation of excitatory postsynaptic membrane potential, negative regulation of myelination, negative regulation of receptor catabolic process, negative regulation of receptor internalization, neuron development, phosphatidylinositol biosynthetic process, phosphatidylinositol dephosphorylation, phospholipid metabolic process, positive regulation of early endosome to late endosome transport, protein dephosphorylation, protein tetramerization, small molecule metabolic process axon, cytoplasm, cytosol, dendrite, dendritic spine, early endosome membrane, nucleus, postsynaptic density, synaptic membrane, synaptic vesicle, vacuolar membrane phosphatidylinositol phosphate phosphatase activity, protein binding, protein homodimerization activity, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human UniProtKB:D3ZA31 MTMR3 GOC UniProtKB {GO:0006661=Reactome:REACT_121025, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0035335=PMID:10733931, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_121287, GO:0005737=GO_REF:0000052, GO:0006470=PMID:10733931, GO:0016020=PMID:10733931, GO:0004438=PMID:10900271, GO:0046856=PMID:10900271, GO:0004722=PMID:10733931, GO:0006644=Reactome:REACT_121175, GO:0004725=PMID:10733931} Q13615 Myotubularin-related protein 3 protein 20130413 {GO:0006661=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0035335=IDA, GO:0046872=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0006470=IDA, GO:0016020=IDA, GO:0004438=IDA, GO:0046856=IDA, GO:0004722=IDA, GO:0006644=TAS, GO:0004725=IDA} peptidyl-tyrosine dephosphorylation, phosphatidylinositol biosynthetic process, phosphatidylinositol dephosphorylation, phospholipid metabolic process, protein dephosphorylation, small molecule metabolic process cytoplasm, cytosol, membrane, nucleolus, nucleus metal ion binding, phosphatidylinositol-3-phosphatase activity, protein serine/threonine phosphatase activity, protein tyrosine phosphatase activity Human MTMR4 GOC UniProtKB {GO:0006661=Reactome:REACT_120918, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0035335=PMID:9736772, GO:0005829=Reactome:REACT_121390, GO:0016791=GO_REF:0000002, GO:0006470=PMID:9736772, GO:0031901=Reactome:REACT_120991, GO:0007179=Reactome:REACT_120850, GO:0004722=Reactome:REACT_120908, GO:0006644=Reactome:REACT_121175, GO:0004725=GO_REF:0000003, GO:0030512=Reactome:REACT_120727} Q9NYA4 Myotubularin-related protein 4 protein 20130413 {GO:0006661=TAS, GO:0044281=TAS, GO:0046872=IEA, GO:0035335=TAS, GO:0005829=TAS, GO:0016791=IEA, GO:0006470=TAS, GO:0031901=TAS, GO:0007179=TAS, GO:0004722=TAS, GO:0006644=TAS, GO:0004725=IEA, GO:0030512=TAS} negative regulation of transforming growth factor beta receptor signaling pathway, peptidyl-tyrosine dephosphorylation, phosphatidylinositol biosynthetic process, phospholipid metabolic process, protein dephosphorylation, small molecule metabolic process, transforming growth factor beta receptor signaling pathway cytosol, early endosome membrane metal ion binding, phosphatase activity, protein serine/threonine phosphatase activity, protein tyrosine phosphatase activity Human MTMR6 GOC UniProtKB {GO:0005737=GO_REF:0000054, GO:0006470=PMID:9736772, GO:0006661=Reactome:REACT_121025, GO:0044281=Reactome:REACT_111217, GO:0004722=PMID:9736772, GO:0005635=GO_REF:0000039, GO:0006644=Reactome:REACT_121175, GO:0015269=PMID:15831468, GO:0035335=PMID:9736772, GO:0004725=PMID:9736772, GO:0005829=Reactome:REACT_121287} Q9Y217 Myotubularin-related protein 6 protein 20130413 {GO:0005737=IDA, GO:0006470=NAS, GO:0006661=TAS, GO:0044281=TAS, GO:0004722=NAS, GO:0005635=IEA, GO:0006644=TAS, GO:0015269=IDA, GO:0035335=NAS, GO:0004725=NAS, GO:0005829=TAS} peptidyl-tyrosine dephosphorylation, phosphatidylinositol biosynthetic process, phospholipid metabolic process, protein dephosphorylation, small molecule metabolic process cytoplasm, cytosol, nuclear envelope calcium-activated potassium channel activity, protein serine/threonine phosphatase activity, protein tyrosine phosphatase activity Human MTMR7 GOC UniProtKB {GO:0016791=GO_REF:0000002, GO:0006470=PMID:9736772, GO:0006661=Reactome:REACT_120918, GO:0016020=GO_REF:0000019, GO:0046855=GO_REF:0000019, GO:0046856=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0006644=Reactome:REACT_121175, GO:0035335=PMID:9736772, GO:0004725=GO_REF:0000002, GO:0005829=Reactome:REACT_121325} Q9Y216 Myotubularin-related protein 7 protein 20130413 {GO:0016791=IEA, GO:0006470=TAS, GO:0006661=TAS, GO:0016020=IEA, GO:0046855=IEA, GO:0046856=IEA, GO:0044281=TAS, GO:0006644=TAS, GO:0035335=TAS, GO:0004725=IEA, GO:0005829=TAS} inositol phosphate dephosphorylation, peptidyl-tyrosine dephosphorylation, phosphatidylinositol biosynthetic process, phosphatidylinositol dephosphorylation, phospholipid metabolic process, protein dephosphorylation, small molecule metabolic process cytosol, membrane phosphatase activity, protein tyrosine phosphatase activity Human MTMR8 UniProtKB UniProtKB {GO:0035556=GO_REF:0000002, GO:0005635=GO_REF:0000039, GO:0004725=GO_REF:0000002} Q96EF0 Myotubularin-related protein 8 protein 20130413 {GO:0035556=IEA, GO:0005635=IEA, GO:0004725=IEA} intracellular signal transduction nuclear envelope protein tyrosine phosphatase activity Human UniProtKB-SubCell:SL-0178 MTMR9 UniProtKB UniProtKB {GO:0005515=PMID:12890864, GO:0016791=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0030234=GO_REF:0000019} Q96QG7 Myotubularin-related protein 9 protein 20120708 {GO:0005515=IPI, GO:0016791=IEA, GO:0005737=IEA, GO:0030234=IEA} cytoplasm enzyme regulator activity, phosphatase activity, protein binding Human UniProtKB:Q59HJ6 MTNR1A BHF-UCL UniProtKB {GO:0043235=PMID:10531408, GO:0005886=Reactome:REACT_22289, GO:0005887=PMID:10531408, GO:0007617=PMID:7946354, GO:0007187=PMID:9645677, GO:0042562=PMID:10531408, GO:0007623=PMID:9645677, GO:0030828=PMID:10531408, GO:0097159=PMID:10531408, GO:0008502=GO_REF:0000002} P48039 Melatonin receptor type 1A protein 20120510 {GO:0043235=IDA, GO:0005886=TAS, GO:0005887=IDA, GO:0007617=TAS, GO:0007187=TAS, GO:0042562=IPI, GO:0007623=TAS, GO:0030828=IDA, GO:0097159=IPI, GO:0008502=IEA} G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, circadian rhythm, mating behavior, positive regulation of cGMP biosynthetic process integral to plasma membrane, plasma membrane, receptor complex hormone binding, melatonin receptor activity, organic cyclic compound binding Human MTNR1B BHF-UCL UniProtKB {GO:0050796=PMID:20668700, GO:0005886=Reactome:REACT_22289, GO:0007187=PMID:7568007, GO:0005887=PMID:7568007, GO:0004930=PMID:7568007, GO:0007268=PMID:7568007, GO:0042593=PMID:20668700, GO:0016021=GO_REF:0000002, GO:0008502=GO_REF:0000002} P49286 Melatonin receptor type 1B protein 20100929 {GO:0050796=IMP, GO:0005886=TAS, GO:0007187=TAS, GO:0005887=TAS, GO:0004930=TAS, GO:0007268=TAS, GO:0042593=IMP, GO:0016021=IEA, GO:0008502=IEA} G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, glucose homeostasis, regulation of insulin secretion, synaptic transmission integral to membrane, integral to plasma membrane, plasma membrane G-protein coupled receptor activity, melatonin receptor activity Human MTO1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0050660=GO_REF:0000002, GO:0070899=GO_REF:0000019, GO:0008033=GO_REF:0000002, GO:0055114=GO_REF:0000002} Q9Y2Z2 Protein MTO1 homolog, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0050660=IEA, GO:0070899=IEA, GO:0008033=IEA, GO:0055114=IEA} mitochondrial tRNA wobble uridine modification, oxidation-reduction process, tRNA processing mitochondrion flavin adenine dinucleotide binding Human UniProtKB-SubCell:SL-0173 MTOR IntAct UniProtKB {GO:0001156=PMID:20543138, GO:0045859=GO_REF:0000019, GO:0051219=PMID:11853878, GO:0005515=PMID:22424946, GO:0016242=GO_REF:0000019, GO:0010831=GO_REF:0000019, GO:0050731=GO_REF:0000019, GO:0005764=PMID:20381137, GO:0007281=GO_REF:0000019, GO:0031529=GO_REF:0000019, GO:0046889=PMID:18762023, GO:0030163=PMID:11853878, GO:0032314=GO_REF:0000019, GO:0046777=PMID:15467718, GO:0007173=Reactome:REACT_9417, GO:0030838=GO_REF:0000019, GO:0031931=PMID:15467718, GO:0018105=PMID:20537536, GO:0016301=PMID:15467718, GO:0032956=PMID:15467718, GO:0018107=GO_REF:0000019, GO:0031669=GO_REF:0000024, GO:0031932=PMID:15467718, GO:0031929=PMID:17028174, GO:0032868=GO_REF:0000019, GO:0005979=GO_REF:0000019, GO:0070438=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0006950=PMID:17028174, GO:0016310=PMID:11853878, GO:0045792=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0051496=GO_REF:0000019, GO:0010507=GO_REF:0000024, GO:0005789=GO_REF:0000039, GO:0016049=PMID:18762023, GO:0040007=PMID:15539461, GO:0008286=Reactome:REACT_498, GO:0051897=GO_REF:0000019, GO:0031998=GO_REF:0000019, GO:0031295=Reactome:REACT_19344, GO:0005741=GO_REF:0000039, GO:0032095=GO_REF:0000019, GO:0005829=Reactome:REACT_147858, GO:0010592=GO_REF:0000019, GO:0005737=PMID:20381137, GO:0008144=GO_REF:0000002, GO:0045945=PMID:20233713, GO:0043200=PMID:18497260, GO:0048011=Reactome:REACT_11061, GO:0043610=GO_REF:0000019, GO:0007584=PMID:15539461, GO:0048015=Reactome:REACT_12464, GO:0051534=GO_REF:0000019, GO:0071456=GO_REF:0000024, GO:0045727=PMID:18762023, GO:0005524=GO_REF:0000037, GO:0012505=PMID:18497260, GO:0007165=PMID:15539461, GO:0000139=GO_REF:0000039, GO:0016020=PMID:11853878, GO:0001938=GO_REF:0000019, GO:0004674=Reactome:REACT_147858, GO:0016605=GO_REF:0000024, GO:0001934=PMID:20233713, GO:0043022=GO_REF:0000019, GO:0001032=PMID:20233713, GO:0006468=PMID:15467718, GO:0001030=PMID:20233713, GO:0005942=PMID:15539461, GO:0001031=PMID:20233713} P42345 Serine/threonine-protein kinase mTOR protein 20130415 {GO:0001156=IDA, GO:0045859=IEA, GO:0051219=IPI, GO:0005515=IPI, GO:0016242=IEA, GO:0010831=IEA, GO:0050731=IEA, GO:0005764=IDA, GO:0007281=IEA, GO:0031529=IEA, GO:0046889=IMP, GO:0030163=TAS, GO:0032314=IEA, GO:0046777=IDA, GO:0007173=TAS, GO:0030838=IEA, GO:0031931=IDA, GO:0018105=IMP, GO:0016301=IDA, GO:0032956=IMP, GO:0018107=IEA, GO:0031669=ISS, GO:0031932=IDA, GO:0031929=IMP, GO:0032868=IEA, GO:0005979=IEA, GO:0070438=IEA, GO:0019904=IEA, GO:0006950=IMP, GO:0016310=IDA, GO:0045792=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:0051496=IEA, GO:0010507=ISS, GO:0005789=IEA, GO:0016049=IDA, GO:0040007=NAS, GO:0008286=TAS, GO:0051897=IEA, GO:0031998=IEA, GO:0031295=TAS, GO:0005741=IEA, GO:0032095=IEA, GO:0005829=TAS, GO:0010592=IEA, GO:0005737=IDA, GO:0008144=IEA, GO:0045945=IMP, GO:0043200=IDA, GO:0048011=TAS, GO:0043610=IEA, GO:0007584=NAS, GO:0048015=TAS, GO:0051534=IEA, GO:0071456=ISS, GO:0045727=IDA, GO:0005524=IEA, GO:0012505=IDA, GO:0007165=NAS, GO:0000139=IEA, GO:0016020=IDA, GO:0001938=IEA, GO:0004674=TAS, GO:0016605=ISS, GO:0001934=IDA, GO:0043022=IEA, GO:0001032=IDA, GO:0006468=IDA, GO:0001030=IDA, GO:0005942=NAS, GO:0001031=IDA} T cell costimulation, TOR signaling cascade, cell growth, cellular response to hypoxia, cellular response to nutrient levels, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, germ cell development, growth, innate immune response, insulin receptor signaling pathway, negative regulation of NFAT protein import into nucleus, negative regulation of autophagy, negative regulation of cell size, negative regulation of macroautophagy, neurotrophin TRK receptor signaling pathway, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, phosphatidylinositol-mediated signaling, phosphorylation, positive regulation of actin filament polymerization, positive regulation of endothelial cell proliferation, positive regulation of lamellipodium assembly, positive regulation of lipid biosynthetic process, positive regulation of myotube differentiation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of protein kinase B signaling cascade, positive regulation of protein phosphorylation, positive regulation of stress fiber assembly, positive regulation of transcription from RNA polymerase III promoter, positive regulation of translation, protein autophosphorylation, protein catabolic process, protein phosphorylation, regulation of Rac GTPase activity, regulation of actin cytoskeleton organization, regulation of carbohydrate utilization, regulation of fatty acid beta-oxidation, regulation of glycogen biosynthetic process, regulation of protein kinase activity, regulation of response to food, response to amino acid stimulus, response to insulin stimulus, response to nutrient, response to stress, ruffle organization, signal transduction Golgi membrane, PML body, TORC1 complex, TORC2 complex, cytoplasm, cytosol, endomembrane system, endoplasmic reticulum membrane, lysosome, mTOR-FKBP12-rapamycin complex, membrane, mitochondrial outer membrane, phosphatidylinositol 3-kinase complex ATP binding, RNA polymerase III type 1 promoter DNA binding, RNA polymerase III type 2 promoter DNA binding, RNA polymerase III type 3 promoter DNA binding, TFIIIC-class transcription factor binding, drug binding, kinase activity, phosphoprotein binding, protein binding, protein domain specific binding, protein serine/threonine kinase activity, ribosome binding Human UniProtKB:Q8N122 MTPAP HPA UniProtKB {GO:0005515=PMID:21903422, GO:0008219=GO_REF:0000037, GO:0006378=PMID:21292163, GO:0005794=GO_REF:0000052, GO:0030145=PMID:21292163, GO:0000287=PMID:21292163, GO:0005886=GO_REF:0000052, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005524=PMID:21292163, GO:0006351=GO_REF:0000037, GO:0042803=PMID:21292163, GO:0042802=PMID:21292163, GO:0002134=PMID:21292163, GO:0005739=GO_REF:0000052, GO:0004652=PMID:21292163, GO:0005737=GO_REF:0000052, GO:0071044=PMID:18172165} Q9NVV4 Poly(A) RNA polymerase, mitochondrial protein 20110516 {GO:0005515=IPI, GO:0008219=IEA, GO:0006378=IDA, GO:0005794=IDA, GO:0030145=IDA, GO:0000287=IDA, GO:0005886=IDA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005524=IDA, GO:0006351=IEA, GO:0042803=IPI, GO:0042802=IPI, GO:0002134=IDA, GO:0005739=IDA, GO:0004652=IDA, GO:0005737=IDA, GO:0071044=IMP} cell death, histone mRNA catabolic process, mRNA polyadenylation, transcription, DNA-dependent Golgi apparatus, cytoplasm, mitochondrion, nucleolus, nucleus, plasma membrane ATP binding, RNA binding, UTP binding, identical protein binding, magnesium ion binding, manganese ion binding, polynucleotide adenylyltransferase activity, protein binding, protein homodimerization activity Human MTPN UniProtKB UniProtKB {GO:0051247=GO_REF:0000024, GO:0030424=GO_REF:0000019, GO:0048471=GO_REF:0000039, GO:0030307=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0005575=GO_REF:0000015, GO:0010557=GO_REF:0000024, GO:2000812=PMID:16895918, GO:0006417=PMID:12031792, GO:0005829=GO_REF:0000024, GO:0021707=GO_REF:0000019, GO:0051092=GO_REF:0000024, GO:0006584=GO_REF:0000019, GO:0030182=PMID:12031792, GO:0016202=PMID:12031792, GO:0016049=PMID:10329199, GO:0043403=GO_REF:0000019, GO:0008290=PMID:16895918, GO:0010613=PMID:10329199, GO:0051146=GO_REF:0000019} P58546 Myotrophin protein 20111213 {GO:0051247=ISS, GO:0030424=IEA, GO:0048471=IEA, GO:0030307=ISS, GO:0005634=ISS, GO:0005575=ND, GO:0010557=ISS, GO:2000812=IDA, GO:0006417=NAS, GO:0005829=ISS, GO:0021707=IEA, GO:0051092=ISS, GO:0006584=IEA, GO:0030182=NAS, GO:0016202=NAS, GO:0016049=IDA, GO:0043403=IEA, GO:0008290=IDA, GO:0010613=IMP, GO:0051146=IEA} catecholamine metabolic process, cell growth, cerebellar granule cell differentiation, neuron differentiation, positive regulation of NF-kappaB transcription factor activity, positive regulation of cardiac muscle hypertrophy, positive regulation of cell growth, positive regulation of macromolecule biosynthetic process, positive regulation of protein metabolic process, regulation of barbed-end actin filament capping, regulation of striated muscle tissue development, regulation of translation, skeletal muscle tissue regeneration, striated muscle cell differentiation F-actin capping protein complex, axon, cellular_component, cytosol, nucleus, perinuclear region of cytoplasm Human UniProtKB:P62775 MTR HPA UniProtKB {GO:0006805=Reactome:REACT_13433, GO:0031419=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0042558=GO_REF:0000002, GO:0008705=GO_REF:0000003, GO:0032259=Reactome:REACT_6946, GO:0007399=PMID:8968737, GO:0005829=Reactome:REACT_6739, GO:0005622=GO_REF:0000002, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000052, GO:0000096=Reactome:REACT_115639, GO:0008270=GO_REF:0000002, GO:0008898=GO_REF:0000002} Q99707 Methionine synthase protein 20111111 {GO:0006805=TAS, GO:0031419=IEA, GO:0044281=TAS, GO:0042558=IEA, GO:0008705=IEA, GO:0032259=TAS, GO:0007399=TAS, GO:0005829=TAS, GO:0005622=IEA, GO:0034641=TAS, GO:0005737=IDA, GO:0000096=TAS, GO:0008270=IEA, GO:0008898=IEA} cellular nitrogen compound metabolic process, methylation, nervous system development, pteridine-containing compound metabolic process, small molecule metabolic process, sulfur amino acid metabolic process, xenobiotic metabolic process cytoplasm, cytosol, intracellular cobalamin binding, homocysteine S-methyltransferase activity, methionine synthase activity, zinc ion binding Human MTRF1 PINC UniProtKB {GO:0005739=GO_REF:0000039, GO:0005737=GO_REF:0000002, GO:0016149=GO_REF:0000002, GO:0006449=PMID:9838146, GO:0003747=PMID:9838146} O75570 Peptide chain release factor 1, mitochondrial protein 20030904 {GO:0005739=IEA, GO:0005737=IEA, GO:0016149=IEA, GO:0006449=TAS, GO:0003747=TAS} regulation of translational termination cytoplasm, mitochondrion translation release factor activity, translation release factor activity, codon specific Human MTRF1L LIFEdb UniProtKB {GO:0005739=GO_REF:0000054, GO:0016149=GO_REF:0000002, GO:0003747=GO_REF:0000002} Q9UGC7 Peptide chain release factor 1-like, mitochondrial protein 20100607 {GO:0005739=IDA, GO:0016149=IEA, GO:0003747=IEA} mitochondrion translation release factor activity, translation release factor activity, codon specific Human MTRNR2L1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005576=GO_REF:0000039} P0CJ68 Humanin-like protein 1 protein 20130413 {GO:0005737=IEA, GO:0005576=IEA} cytoplasm, extracellular region Human UniProtKB-SubCell:SL-0086 MTRR HPA UniProtKB {GO:0050661=PMID:9501215, GO:0006805=Reactome:REACT_13433, GO:0005506=GO_REF:0000002, GO:0010181=PMID:9501215, GO:0050660=PMID:17892308, GO:0005730=GO_REF:0000052, GO:0009086=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0032259=Reactome:REACT_6946, GO:0005829=Reactome:REACT_6739, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000052, GO:0030586=PMID:17892308, GO:0000096=Reactome:REACT_115639, GO:0003958=GO_REF:0000033, GO:0016709=GO_REF:0000033, GO:0016491=GO_REF:0000002, GO:0006555=PMID:9501215, GO:0016723=PMID:17892308, GO:0045111=GO_REF:0000052, GO:0055114=PMID:9501215} Q9UBK8 Methionine synthase reductase protein 20111111 {GO:0050661=TAS, GO:0006805=TAS, GO:0005506=IEA, GO:0010181=TAS, GO:0050660=IDA, GO:0005730=IDA, GO:0009086=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0032259=TAS, GO:0005829=TAS, GO:0034641=TAS, GO:0005737=IDA, GO:0030586=TAS, GO:0000096=TAS, GO:0003958=IBA, GO:0016709=IBA, GO:0016491=IEA, GO:0006555=TAS, GO:0016723=IDA, GO:0045111=IDA, GO:0055114=TAS} cellular nitrogen compound metabolic process, methionine biosynthetic process, methionine metabolic process, methylation, oxidation-reduction process, small molecule metabolic process, sulfur amino acid metabolic process, xenobiotic metabolic process cytoplasm, cytosol, intermediate filament cytoskeleton, nucleolus, nucleus "FMN binding, NADP binding, NADPH-hemoprotein reductase activity, methionine synthase"" reductase activity, flavin adenine dinucleotide binding, iron ion binding, oxidoreductase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen, oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor""" Human MTSS1 IntAct UniProtKB {GO:0072160=GO_REF:0000024, GO:0005515=PMID:15383276, GO:0017124=GO_REF:0000002, GO:0030036=PMID:12082544, GO:0030035=PMID:12570871, GO:0050680=GO_REF:0000024, GO:0006928=PMID:12570871, GO:0030139=PMID:12570871, GO:0015629=PMID:12570871, GO:0042802=PMID:14752106, GO:0061333=GO_REF:0000024, GO:0005737=PMID:12570871, GO:0030041=GO_REF:0000019, GO:2001013=GO_REF:0000024, GO:0046847=GO_REF:0000002, GO:0007155=PMID:12570871, GO:0008093=GO_REF:0000002, GO:0072102=GO_REF:0000024, GO:0005102=PMID:12570871, GO:0003779=GO_REF:0000002, GO:0001726=PMID:12570871, GO:0071498=GO_REF:0000024, GO:0003785=PMID:12570871, GO:0007165=GO_REF:0000002, GO:0007169=PMID:12570871} O43312 Metastasis suppressor protein 1 protein 20130415 {GO:0072160=ISS, GO:0005515=IPI, GO:0017124=IEA, GO:0030036=TAS, GO:0030035=NAS, GO:0050680=ISS, GO:0006928=NAS, GO:0030139=TAS, GO:0015629=IDA, GO:0042802=IPI, GO:0061333=ISS, GO:0005737=TAS, GO:0030041=IEA, GO:2001013=ISS, GO:0046847=IEA, GO:0007155=NAS, GO:0008093=IEA, GO:0072102=ISS, GO:0005102=IPI, GO:0003779=IEA, GO:0001726=NAS, GO:0071498=ISS, GO:0003785=IDA, GO:0007165=IEA, GO:0007169=TAS} actin cytoskeleton organization, actin filament polymerization, cell adhesion, cellular component movement, cellular response to fluid shear stress, epithelial cell proliferation involved in renal tubule morphogenesis, filopodium assembly, glomerulus morphogenesis, microspike assembly, negative regulation of epithelial cell proliferation, nephron tubule epithelial cell differentiation, renal tubule morphogenesis, signal transduction, transmembrane receptor protein tyrosine kinase signaling pathway actin cytoskeleton, cytoplasm, endocytic vesicle, ruffle SH3 domain binding, actin binding, actin monomer binding, cytoskeletal adaptor activity, identical protein binding, protein binding, receptor binding Human UniProtKB:O43312 MTTP InterPro UniProtKB {GO:0006629=Reactome:REACT_602, GO:0005791=GO_REF:0000019, GO:0042632=GO_REF:0000019, GO:0005794=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0031988=GO_REF:0000019, GO:0031528=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0031526=GO_REF:0000019, GO:0008289=GO_REF:0000037, GO:0051592=GO_REF:0000019, GO:0016323=GO_REF:0000019, GO:0042953=GO_REF:0000019, GO:0042157=Reactome:REACT_6841, GO:0006497=GO_REF:0000019, GO:0005788=Reactome:REACT_6908, GO:0006641=GO_REF:0000019, GO:0034185=GO_REF:0000019, GO:0005319=GO_REF:0000002} Q6P5T3 MTTP protein protein 20130413 {GO:0006629=TAS, GO:0005791=IEA, GO:0042632=IEA, GO:0005794=IEA, GO:0046982=IEA, GO:0031988=IEA, GO:0031528=IEA, GO:0044281=TAS, GO:0031526=IEA, GO:0008289=IEA, GO:0051592=IEA, GO:0016323=IEA, GO:0042953=IEA, GO:0042157=TAS, GO:0006497=IEA, GO:0005788=TAS, GO:0006641=IEA, GO:0034185=IEA, GO:0005319=IEA} cholesterol homeostasis, lipid metabolic process, lipoprotein metabolic process, lipoprotein transport, protein lipidation, response to calcium ion, small molecule metabolic process, triglyceride metabolic process Golgi apparatus, basolateral plasma membrane, brush border membrane, endoplasmic reticulum lumen, membrane-bounded vesicle, microvillus membrane, rough endoplasmic reticulum apolipoprotein binding, lipid binding, lipid transporter activity, protein heterodimerization activity Human InterPro:IPR001747|InterPro:IPR015816|InterPro:IPR015819 MTUS1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0005794=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0005815=GO_REF:0000039, GO:0071375=GO_REF:0000019, GO:0005874=GO_REF:0000037, GO:0005819=GO_REF:0000039, GO:0005634=GO_REF:0000039} Q9ULD2 Microtubule-associated tumor suppressor 1 protein 20130413 {GO:0005739=IEA, GO:0005794=IEA, GO:0005886=IEA, GO:0005815=IEA, GO:0071375=IEA, GO:0005874=IEA, GO:0005819=IEA, GO:0005634=IEA} cellular response to peptide hormone stimulus Golgi apparatus, microtubule, microtubule organizing center, mitochondrion, nucleus, plasma membrane, spindle Human UniProtKB-SubCell:SL-0039 MTUS2 UniProtKB UniProtKB {GO:0008017=PMID:19543227, GO:0005515=PMID:19543227, GO:0005881=PMID:19543227, GO:0005813=PMID:19543227, GO:0042803=PMID:19543227} Q5JR59 Microtubule-associated tumor suppressor candidate 2 protein 20090804 {GO:0008017=IDA, GO:0005515=IPI, GO:0005881=IDA, GO:0005813=IDA, GO:0042803=IPI} centrosome, cytoplasmic microtubule microtubule binding, protein binding, protein homodimerization activity Human MTX1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0006626=Reactome:REACT_118595, GO:0005743=GO_REF:0000019, GO:0005741=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015} Q13505 Metaxin-1 protein 20081203 {GO:0005739=IDA, GO:0006626=TAS, GO:0005743=IEA, GO:0005741=IEA, GO:0016021=IEA, GO:0044267=TAS} cellular protein metabolic process, protein targeting to mitochondrion integral to membrane, mitochondrial inner membrane, mitochondrial outer membrane, mitochondrion Human MTX2 InterPro UniProtKB {GO:0005739=GO_REF:0000019, GO:0006626=GO_REF:0000002, GO:0005741=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0006839=PMID:10381257} Q8IZ68 Metaxin-2 protein 20130413 {GO:0005739=IEA, GO:0006626=IEA, GO:0005741=IEA, GO:0044267=TAS, GO:0006839=TAS} cellular protein metabolic process, mitochondrial transport, protein targeting to mitochondrion mitochondrial outer membrane, mitochondrion Human InterPro:IPR019564 MTX3 UniProtKB UniProtKB {GO:0006626=GO_REF:0000002, GO:0005741=GO_REF:0000039} Q5HYI7 Metaxin-3 protein 20130413 {GO:0006626=IEA, GO:0005741=IEA} protein targeting to mitochondrion mitochondrial outer membrane Human UniProtKB-SubCell:SL-0172 MUC1 BHF-UCL UniProtKB {GO:0003712=PMID:15710329, GO:0090240=PMID:15710329, GO:0005515=PMID:21798038, GO:0043066=PMID:15710329, GO:0000790=PMID:15710329, GO:0009986=GO_REF:0000033, GO:0005796=Reactome:REACT_116107, GO:0016266=Reactome:REACT_115835, GO:0005576=GO_REF:0000039, GO:0043618=PMID:15710329, GO:0000978=PMID:15710329, GO:0002039=PMID:15710329, GO:0016324=GO_REF:0000033, GO:0005737=GO_REF:0000033, GO:0010944=PMID:15710329, GO:0005887=PMID:1697589, GO:0006978=PMID:15710329, GO:0044267=Reactome:REACT_17015, GO:0036003=PMID:15710329, GO:0043687=Reactome:REACT_22161, GO:0006977=PMID:15710329} P15941 Mucin-1 protein 20111212 {GO:0003712=IDA, GO:0090240=IDA, GO:0005515=IPI, GO:0043066=IDA, GO:0000790=IDA, GO:0009986=IBA, GO:0005796=TAS, GO:0016266=TAS, GO:0005576=IEA, GO:0043618=IDA, GO:0000978=IDA, GO:0002039=IPI, GO:0016324=IBA, GO:0005737=IBA, GO:0010944=IDA, GO:0005887=TAS, GO:0006978=IDA, GO:0044267=TAS, GO:0036003=IDA, GO:0043687=TAS, GO:0006977=IDA} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, O-glycan processing, cellular protein metabolic process, negative regulation of apoptotic process, negative regulation of transcription by competitive promoter binding, positive regulation of histone H4 acetylation, positive regulation of transcription from RNA polymerase II promoter in response to stress, post-translational protein modification, regulation of transcription from RNA polymerase II promoter in response to stress Golgi lumen, apical plasma membrane, cell surface, cytoplasm, extracellular region, integral to plasma membrane, nuclear chromatin RNA polymerase II core promoter proximal region sequence-specific DNA binding, p53 binding, protein binding, transcription cofactor activity Human MUC12 Reactome UniProtKB {GO:0003674=GO_REF:0000015, GO:0005796=Reactome:REACT_116107, GO:0005887=PMID:10463611, GO:0016266=Reactome:REACT_115835, GO:0044267=Reactome:REACT_17015, GO:0001558=PMID:10463611, GO:0043687=Reactome:REACT_22161} Q9UKN1 Mucin-12 protein 20130301 {GO:0003674=ND, GO:0005796=TAS, GO:0005887=NAS, GO:0016266=TAS, GO:0044267=TAS, GO:0001558=NAS, GO:0043687=TAS} O-glycan processing, cellular protein metabolic process, post-translational protein modification, regulation of cell growth Golgi lumen, integral to plasma membrane molecular_function Human MUC13 Reactome UniProtKB {GO:0016324=GO_REF:0000039, GO:0005796=Reactome:REACT_116107, GO:0016266=Reactome:REACT_115835, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q9H3R2 Mucin-13 protein 20130301 {GO:0016324=IEA, GO:0005796=TAS, GO:0016266=TAS, GO:0005576=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0043687=TAS} O-glycan processing, cellular protein metabolic process, post-translational protein modification Golgi lumen, apical plasma membrane, extracellular region, integral to membrane Human MUC16 Reactome UniProtKB {GO:0005515=PMID:14676194, GO:0005886=GO_REF:0000039, GO:0005796=Reactome:REACT_116107, GO:0016266=Reactome:REACT_115835, GO:0016021=GO_REF:0000037, GO:0007155=PMID:14676194, GO:0044267=Reactome:REACT_17015, GO:0005615=GO_REF:0000039, GO:0009897=GO_REF:0000019, GO:0043687=Reactome:REACT_22161, GO:0019898=PMID:12766047} Q8WXI7 Mucin-16 protein 20130301 {GO:0005515=IPI, GO:0005886=IEA, GO:0005796=TAS, GO:0016266=TAS, GO:0016021=IEA, GO:0007155=NAS, GO:0044267=TAS, GO:0005615=IEA, GO:0009897=IEA, GO:0043687=TAS, GO:0019898=IDA} O-glycan processing, cell adhesion, cellular protein metabolic process, post-translational protein modification Golgi lumen, external side of plasma membrane, extracellular space, extrinsic to membrane, integral to membrane, plasma membrane protein binding Human MUC2 Reactome UniProtKB {GO:0005515=PMID:19359471, GO:0005796=Reactome:REACT_116107, GO:0070703=GO_REF:0000024, GO:0070702=GO_REF:0000024, GO:0016266=Reactome:REACT_115835, GO:0005576=GO_REF:0000038, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q02817 Mucin-2 protein 20130301 {GO:0005515=IPI, GO:0005796=TAS, GO:0070703=ISS, GO:0070702=ISS, GO:0016266=TAS, GO:0005576=IEA, GO:0044267=TAS, GO:0043687=TAS} O-glycan processing, cellular protein metabolic process, post-translational protein modification Golgi lumen, extracellular region, inner mucus layer, outer mucus layer protein binding Human MUC20 Reactome UniProtKB {GO:0000187=GO_REF:0000019, GO:0016324=GO_REF:0000039, GO:0009925=PMID:15314156, GO:0048012=GO_REF:0000019, GO:0005796=Reactome:REACT_116107, GO:0016266=Reactome:REACT_115835, GO:0031528=GO_REF:0000039, GO:0051260=PMID:15314156, GO:0005576=GO_REF:0000039, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q8N307 Mucin-20 protein 20130301 {GO:0000187=IEA, GO:0016324=IEA, GO:0009925=IDA, GO:0048012=IEA, GO:0005796=TAS, GO:0016266=TAS, GO:0031528=IEA, GO:0051260=IDA, GO:0005576=IEA, GO:0044267=TAS, GO:0043687=TAS} O-glycan processing, activation of MAPK activity, cellular protein metabolic process, hepatocyte growth factor receptor signaling pathway, post-translational protein modification, protein homooligomerization Golgi lumen, apical plasma membrane, basal plasma membrane, extracellular region, microvillus membrane Human MUC4 Reactome UniProtKB {GO:0005176=PMID:10024507, GO:0008150=GO_REF:0000015, GO:0016020=PMID:10920259, GO:0030197=PMID:10920259, GO:0007160=GO_REF:0000002, GO:0005796=Reactome:REACT_116107, GO:0005887=PMID:10024507, GO:0005578=PMID:10920259, GO:0016266=Reactome:REACT_115835, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0005201=GO_REF:0000029} Q99102 Mucin-4 protein 20130301 {GO:0005176=TAS, GO:0008150=ND, GO:0016020=NAS, GO:0030197=NAS, GO:0007160=IEA, GO:0005796=TAS, GO:0005887=TAS, GO:0005578=NAS, GO:0016266=TAS, GO:0044267=TAS, GO:0043687=TAS, GO:0005201=NAS} O-glycan processing, biological_process, cell-matrix adhesion, cellular protein metabolic process, post-translational protein modification Golgi lumen, integral to plasma membrane, membrane, proteinaceous extracellular matrix ErbB-2 class receptor binding, extracellular matrix constituent, lubricant activity, extracellular matrix structural constituent Human MUC5AC Reactome UniProtKB {GO:0005796=Reactome:REACT_116107, GO:0007586=GO_REF:0000029, GO:0044464=GO_REF:0000019, GO:0016266=Reactome:REACT_115835, GO:0043205=PMID:14749330, GO:0043206=PMID:10611155, GO:0007155=GO_REF:0000029, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0005201=PMID:7513696} P98088 Mucin-5AC protein 20130301 {GO:0005796=TAS, GO:0007586=NAS, GO:0044464=IEA, GO:0016266=TAS, GO:0043205=IDA, GO:0043206=IDA, GO:0007155=NAS, GO:0044267=TAS, GO:0043687=TAS, GO:0005201=TAS} O-glycan processing, cell adhesion, cellular protein metabolic process, digestion, extracellular fibril organization, post-translational protein modification Golgi lumen, cell part, fibril extracellular matrix structural constituent Human MUC5B Reactome UniProtKB {GO:0005515=PMID:1718282, GO:0005796=Reactome:REACT_116107, GO:0016266=Reactome:REACT_115835, GO:0005576=GO_REF:0000029, GO:0007155=GO_REF:0000029, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0005201=GO_REF:0000029} Q9HC84 Mucin-5B protein 20130301 {GO:0005515=IPI, GO:0005796=TAS, GO:0016266=TAS, GO:0005576=NAS, GO:0007155=NAS, GO:0044267=TAS, GO:0043687=TAS, GO:0005201=NAS} O-glycan processing, cell adhesion, cellular protein metabolic process, post-translational protein modification Golgi lumen, extracellular region extracellular matrix structural constituent, protein binding Human MUC6 Reactome UniProtKB {GO:0030277=PMID:7680650, GO:0005796=Reactome:REACT_116107, GO:0016266=Reactome:REACT_115835, GO:0005576=GO_REF:0000029, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0005201=PMID:7680650} Q6W4X9 Mucin-6 protein 20130301 {GO:0030277=NAS, GO:0005796=TAS, GO:0016266=TAS, GO:0005576=NAS, GO:0044267=TAS, GO:0043687=TAS, GO:0005201=NAS} O-glycan processing, cellular protein metabolic process, maintenance of gastrointestinal epithelium, post-translational protein modification Golgi lumen, extracellular region extracellular matrix structural constituent Human MUC7 IntAct UniProtKB {GO:0005515=PMID:16203048, GO:0005796=Reactome:REACT_116107, GO:0016266=Reactome:REACT_115835, GO:0005576=GO_REF:0000039, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q8TAX7 Mucin-7 protein 20130415 {GO:0005515=IPI, GO:0005796=TAS, GO:0016266=TAS, GO:0005576=IEA, GO:0044267=TAS, GO:0043687=TAS} O-glycan processing, cellular protein metabolic process, post-translational protein modification Golgi lumen, extracellular region protein binding Human UniProtKB:P15515 MUL1 HPA UniProtKB {GO:0005515=PMID:19060904, GO:0030308=PMID:18591963, GO:0004842=PMID:18213395, GO:0016567=PMID:18213395, GO:0000266=PMID:18207745, GO:0006919=PMID:18591963, GO:0016925=GO_REF:0000041, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006917=PMID:18591963, GO:0007257=PMID:18591963, GO:0090141=PMID:19407830, GO:0042802=PMID:18591963, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0010637=PMID:19407830, GO:0019789=PMID:19407830, GO:0008270=GO_REF:0000002, GO:0004871=PMID:12761501, GO:0031307=PMID:18213395, GO:0043123=PMID:12761501, GO:0031625=PMID:19407830, GO:0051646=PMID:18213395, GO:0005777=PMID:18207745} Q969V5 Mitochondrial ubiquitin ligase activator of NFKB 1 protein 20101115 {GO:0005515=IPI, GO:0030308=IDA, GO:0004842=IDA, GO:0016567=IDA, GO:0000266=IMP, GO:0006919=IDA, GO:0016925=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006917=IDA, GO:0007257=IDA, GO:0090141=IDA, GO:0042802=IPI, GO:0005739=IDA, GO:0005737=IDA, GO:0010637=IDA, GO:0019789=IDA, GO:0008270=IEA, GO:0004871=IMP, GO:0031307=IDA, GO:0043123=IMP, GO:0031625=IPI, GO:0051646=IMP, GO:0005777=IDA} activation of JUN kinase activity, activation of cysteine-type endopeptidase activity involved in apoptotic process, induction of apoptosis, mitochondrial fission, mitochondrion localization, negative regulation of cell growth, negative regulation of mitochondrial fusion, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of mitochondrial fission, protein sumoylation, protein ubiquitination cytoplasm, integral to mitochondrial outer membrane, mitochondrion, nucleolus, nucleus, peroxisome SUMO ligase activity, identical protein binding, protein binding, signal transducer activity, ubiquitin protein ligase binding, ubiquitin-protein ligase activity, zinc ion binding Human MUM1 UniProtKB UniProtKB {GO:0005515=PMID:20347427, GO:0006281=PMID:20347427, GO:0006325=PMID:20347427, GO:0031491=PMID:20347427, GO:0005634=PMID:20347427} Q2TAK8 PWWP domain-containing protein MUM1 protein 20100408 {GO:0005515=IPI, GO:0006281=IMP, GO:0006325=IMP, GO:0031491=IDA, GO:0005634=IDA} DNA repair, chromatin organization nucleus nucleosome binding, protein binding Human MUM1L1 null null {} null null null null {} null null null MURC ENSEMBL UniProtKB {GO:0030018=GO_REF:0000019, GO:0007517=GO_REF:0000037, GO:0045944=GO_REF:0000019, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q5BKX8 Muscle-related coiled-coil protein protein 20130413 {GO:0030018=IEA, GO:0007517=IEA, GO:0045944=IEA, GO:0030154=IEA, GO:0006351=IEA} cell differentiation, muscle organ development, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent Z disc Human Ensembl:ENSMUSP00000030033 MUS81 UniProtKB UniProtKB {GO:0005515=PMID:19596236, GO:0004518=GO_REF:0000002, GO:0006281=PMID:19596235, GO:0005730=GO_REF:0000039, GO:0048257=PMID:19595721, GO:0006310=GO_REF:0000037, GO:0006259=GO_REF:0000002, GO:0003824=GO_REF:0000002, GO:0003677=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q96NY9 Crossover junction endonuclease MUS81 protein 20090811 {GO:0005515=IPI, GO:0004518=IEA, GO:0006281=IMP, GO:0005730=IEA, GO:0048257=IMP, GO:0006310=IEA, GO:0006259=IEA, GO:0003824=IEA, GO:0003677=IEA, GO:0046872=IEA} DNA metabolic process, DNA recombination, DNA repair nucleolus 3'-flap endonuclease activity, DNA binding, catalytic activity, metal ion binding, nuclease activity, protein binding Human UniProtKB:Q8IY92 MUSK InterPro UniProtKB {GO:0005515=PMID:22939624, GO:0006355=GO_REF:0000019, GO:0031594=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0005524=GO_REF:0000002, GO:2000541=GO_REF:0000024, GO:0010628=GO_REF:0000024, GO:0004672=GO_REF:0000002, GO:0046777=GO_REF:0000024, GO:0043525=GO_REF:0000019, GO:0005887=GO_REF:0000024, GO:0007528=GO_REF:0000024, GO:0045211=GO_REF:0000024, GO:0001934=GO_REF:0000024, GO:0007613=GO_REF:0000024, GO:0004713=GO_REF:0000024, GO:0004714=GO_REF:0000003, GO:0008582=GO_REF:0000024, GO:0007169=PMID:7546737, GO:0071340=GO_REF:0000024} Q5VZW9 Muscle, skeletal receptor tyrosine-protein kinase protein 20130413 {GO:0005515=IPI, GO:0006355=IEA, GO:0031594=ISS, GO:0030054=IEA, GO:0005524=IEA, GO:2000541=ISS, GO:0010628=ISS, GO:0004672=IEA, GO:0046777=ISS, GO:0043525=IEA, GO:0005887=ISS, GO:0007528=ISS, GO:0045211=ISS, GO:0001934=ISS, GO:0007613=ISS, GO:0004713=ISS, GO:0004714=IEA, GO:0008582=ISS, GO:0007169=TAS, GO:0071340=ISS} memory, neuromuscular junction development, positive regulation of gene expression, positive regulation of neuron apoptotic process, positive regulation of protein geranylgeranylation, positive regulation of protein phosphorylation, protein autophosphorylation, regulation of synaptic growth at neuromuscular junction, regulation of transcription, DNA-dependent, skeletal muscle acetylcholine-gated channel clustering, transmembrane receptor protein tyrosine kinase signaling pathway cell junction, integral to plasma membrane, neuromuscular junction, postsynaptic membrane ATP binding, protein binding, protein kinase activity, protein tyrosine kinase activity, transmembrane receptor protein tyrosine kinase activity Human InterPro:IPR000719|InterPro:IPR017441 MUSTN1 ENSEMBL UniProtKB {GO:0005654=GO_REF:0000019, GO:0030326=GO_REF:0000019, GO:0042246=GO_REF:0000019} Q8IVN3 Musculoskeletal embryonic nuclear protein 1 protein 20130413 {GO:0005654=IEA, GO:0030326=IEA, GO:0042246=IEA} embryonic limb morphogenesis, tissue regeneration nucleoplasm Human Ensembl:ENSRNOP00000023330 MUT Reactome UniProtKB {GO:0005739=PMID:2567699, GO:0072341=PMID:20031578, GO:0006635=Reactome:REACT_1473, GO:0004494=GO_REF:0000003, GO:0031419=GO_REF:0000037, GO:0005759=Reactome:REACT_19, GO:0019626=Reactome:REACT_993, GO:0044281=Reactome:REACT_111217, GO:0009791=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0050667=PMID:20031578, GO:0046872=GO_REF:0000037} P22033 Methylmalonyl-CoA mutase, mitochondrial protein 20130220 {GO:0005739=TAS, GO:0072341=IDA, GO:0006635=TAS, GO:0004494=IEA, GO:0031419=IEA, GO:0005759=TAS, GO:0019626=TAS, GO:0044281=TAS, GO:0009791=IEA, GO:0044255=TAS, GO:0050667=IDA, GO:0046872=IEA} cellular lipid metabolic process, fatty acid beta-oxidation, homocysteine metabolic process, post-embryonic development, short-chain fatty acid catabolic process, small molecule metabolic process mitochondrial matrix, mitochondrion cobalamin binding, metal ion binding, methylmalonyl-CoA mutase activity, modified amino acid binding Human MUTYH HPA UniProtKB {GO:0032408=PMID:11801590, GO:0005515=PMID:11801590, GO:0032407=PMID:11801590, GO:0032406=PMID:11801590, GO:0051539=GO_REF:0000037, GO:0032405=PMID:11801590, GO:0005634=GO_REF:0000052, GO:0046872=GO_REF:0000037, GO:0005739=GO_REF:0000019, GO:0004519=GO_REF:0000002, GO:0006281=Reactome:REACT_216, GO:0016787=GO_REF:0000002, GO:0045007=Reactome:REACT_2176, GO:0006284=Reactome:REACT_1104, GO:0016798=GO_REF:0000037, GO:0006285=Reactome:REACT_804, GO:0005654=Reactome:REACT_1894, GO:0006298=PMID:7823963} Q9UIF7 A/G-specific adenine DNA glycosylase protein 20080818 {GO:0032408=IDA, GO:0005515=IPI, GO:0032407=IDA, GO:0032406=IDA, GO:0051539=IEA, GO:0032405=IDA, GO:0005634=IDA, GO:0046872=IEA, GO:0005739=IEA, GO:0004519=IEA, GO:0006281=TAS, GO:0016787=IEA, GO:0045007=TAS, GO:0006284=TAS, GO:0016798=IEA, GO:0006285=TAS, GO:0005654=TAS, GO:0006298=TAS} DNA repair, base-excision repair, base-excision repair, AP site formation, depurination, mismatch repair mitochondrion, nucleoplasm, nucleus 4 iron, 4 sulfur cluster binding, MutLalpha complex binding, MutLbeta complex binding, MutSalpha complex binding, MutSbeta complex binding, endonuclease activity, hydrolase activity, hydrolase activity, acting on glycosyl bonds, metal ion binding, protein binding Human MVD Reactome UniProtKB {GO:0006695=Reactome:REACT_9405, GO:0008284=PMID:9270019, GO:0016301=GO_REF:0000038, GO:0004163=Reactome:REACT_9488, GO:0030544=PMID:12646231, GO:0044281=Reactome:REACT_111217, GO:0008299=PMID:11792727, GO:0005524=GO_REF:0000037, GO:0042803=PMID:8626466, GO:0005777=PMID:14972328, GO:0005829=Reactome:REACT_147863} P53602 Diphosphomevalonate decarboxylase protein 20130213 {GO:0006695=TAS, GO:0008284=IMP, GO:0016301=IEA, GO:0004163=TAS, GO:0030544=IPI, GO:0044281=TAS, GO:0008299=IDA, GO:0005524=IEA, GO:0042803=IDA, GO:0005777=IDA, GO:0005829=TAS} cholesterol biosynthetic process, isoprenoid biosynthetic process, positive regulation of cell proliferation, small molecule metabolic process cytosol, peroxisome ATP binding, Hsp70 protein binding, diphosphomevalonate decarboxylase activity, kinase activity, protein homodimerization activity Human MVK BHF-UCL UniProtKB {GO:0006695=Reactome:REACT_9405, GO:0005737=GO_REF:0000052, GO:0050728=PMID:16732551, GO:0004496=Reactome:REACT_9448, GO:0019287=GO_REF:0000041, GO:0044281=Reactome:REACT_111217, GO:0008299=PMID:14730012, GO:0005524=GO_REF:0000037, GO:0042802=PMID:16189514, GO:0005829=Reactome:REACT_147902, GO:0005777=PMID:14730012} Q03426 Mevalonate kinase protein 20120622 {GO:0006695=TAS, GO:0005737=IDA, GO:0050728=IMP, GO:0004496=TAS, GO:0019287=IEA, GO:0044281=TAS, GO:0008299=IDA, GO:0005524=IEA, GO:0042802=IPI, GO:0005829=TAS, GO:0005777=IDA} cholesterol biosynthetic process, isopentenyl diphosphate biosynthetic process, mevalonate pathway, isoprenoid biosynthetic process, negative regulation of inflammatory response, small molecule metabolic process cytoplasm, cytosol, peroxisome ATP binding, identical protein binding, mevalonate kinase activity Human MVP HPA UniProtKB {GO:0038127=PMID:15133037, GO:0005515=PMID:15133037, GO:0005737=GO_REF:0000052, GO:0048471=PMID:16441665, GO:0023057=PMID:16441665, GO:0005643=GO_REF:0000039, GO:0030529=GO_REF:0000037, GO:0005634=PMID:16441665, GO:0051028=GO_REF:0000037, GO:0005856=PMID:16441665, GO:0015031=GO_REF:0000037} Q14764 Major vault protein protein 20120912 {GO:0038127=IDA, GO:0005515=IPI, GO:0005737=IDA, GO:0048471=IDA, GO:0023057=IDA, GO:0005643=IEA, GO:0030529=IEA, GO:0005634=IDA, GO:0051028=IEA, GO:0005856=IDA, GO:0015031=IEA} ERBB signaling pathway, mRNA transport, negative regulation of signaling, protein transport cytoplasm, cytoskeleton, nuclear pore, nucleus, perinuclear region of cytoplasm, ribonucleoprotein complex protein binding Human MX1 IntAct UniProtKB {GO:0005515=PMID:15757897, GO:0048471=PMID:15047845, GO:0019221=Reactome:REACT_25229, GO:0003924=GO_REF:0000002, GO:0006952=PMID:2154602, GO:0005634=GO_REF:0000039, GO:0006917=PMID:9389754, GO:0005525=GO_REF:0000037, GO:0009615=PMID:15047845, GO:0005829=Reactome:REACT_25192, GO:0007165=PMID:9389754, GO:0051607=GO_REF:0000037, GO:0005737=PMID:21859714, GO:0060337=Reactome:REACT_25162, GO:0045087=PMID:16202617, GO:0005789=GO_REF:0000039, GO:0034340=PMID:21859714, GO:0045071=PMID:16202617} P20591 Interferon-induced GTP-binding protein Mx1 protein 20130415 {GO:0005515=IPI, GO:0048471=IDA, GO:0019221=TAS, GO:0003924=IEA, GO:0006952=TAS, GO:0005634=IEA, GO:0006917=TAS, GO:0005525=IEA, GO:0009615=IMP, GO:0005829=TAS, GO:0007165=TAS, GO:0051607=IEA, GO:0005737=IDA, GO:0060337=TAS, GO:0045087=TAS, GO:0005789=IEA, GO:0034340=TAS, GO:0045071=IDA} cytokine-mediated signaling pathway, defense response, defense response to virus, induction of apoptosis, innate immune response, negative regulation of viral genome replication, response to type I interferon, response to virus, signal transduction, type I interferon-mediated signaling pathway cytoplasm, cytosol, endoplasmic reticulum membrane, nucleus, perinuclear region of cytoplasm GTP binding, GTPase activity, protein binding Human UniProtKB:Q9Y210 MX2 GOC UniProtKB {GO:0019221=Reactome:REACT_25229, GO:0003924=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0006952=PMID:8798556, GO:0005525=PMID:15184662, GO:0015031=GO_REF:0000037, GO:0005829=Reactome:REACT_25192, GO:0006184=PMID:8798556, GO:0005737=GO_REF:0000052, GO:0060337=Reactome:REACT_25162, GO:0005643=PMID:15184662, GO:0051726=PMID:15184662, GO:0051028=GO_REF:0000037, GO:0046822=PMID:15184662} P20592 Interferon-induced GTP-binding protein Mx2 protein 20130413 {GO:0019221=TAS, GO:0003924=IEA, GO:0005634=IDA, GO:0006952=TAS, GO:0005525=IMP, GO:0015031=IEA, GO:0005829=TAS, GO:0006184=TAS, GO:0005737=IDA, GO:0060337=TAS, GO:0005643=IDA, GO:0051726=IMP, GO:0051028=IEA, GO:0046822=IMP} GTP catabolic process, cytokine-mediated signaling pathway, defense response, mRNA transport, protein transport, regulation of cell cycle, regulation of nucleocytoplasmic transport, type I interferon-mediated signaling pathway cytoplasm, cytosol, nuclear pore, nucleus GTP binding, GTPase activity Human MXD1 HPA UniProtKB {GO:0003712=PMID:7829091, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0003700=PMID:8425218, GO:0008283=PMID:7829091, GO:0003714=PMID:8425218, GO:0005730=GO_REF:0000052, GO:0046983=GO_REF:0000002, GO:0007275=PMID:7829091, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q05195 Max dimerization protein 1 protein 20101115 {GO:0003712=TAS, GO:0005739=IDA, GO:0005737=IDA, GO:0003700=TAS, GO:0008283=TAS, GO:0003714=TAS, GO:0005730=IDA, GO:0046983=IEA, GO:0007275=TAS, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA} cell proliferation, multicellular organismal development, transcription, DNA-dependent cytoplasm, mitochondrion, nucleolus, nucleus DNA binding, protein dimerization activity, sequence-specific DNA binding transcription factor activity, transcription cofactor activity, transcription corepressor activity Human MXD3 UniProtKB UniProtKB {GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0045892=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q9BW11 Max dimerization protein 3 protein 20130413 {GO:0046983=IEA, GO:0005634=IEA, GO:0045892=IEA, GO:0003677=IEA, GO:0006351=IEA} negative regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, protein dimerization activity Human UniProtKB-SubCell:SL-0191 MXD4 PINC UniProtKB {GO:0008285=PMID:8521822, GO:0003714=PMID:8521822, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0000122=PMID:8521822, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q14582 Max dimerization protein 4 protein 20030904 {GO:0008285=TAS, GO:0003714=TAS, GO:0046983=IEA, GO:0005634=IEA, GO:0000122=TAS, GO:0003677=IEA, GO:0006351=IEA} negative regulation of cell proliferation, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding, protein dimerization activity, transcription corepressor activity Human MXI1 PINC UniProtKB {GO:0008285=PMID:9624006, GO:0003714=PMID:8425219, GO:0046983=GO_REF:0000002, GO:0042994=PMID:8425219, GO:0005634=GO_REF:0000039, GO:0000122=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P50539 Max-interacting protein 1 protein 20030904 {GO:0008285=TAS, GO:0003714=TAS, GO:0046983=IEA, GO:0042994=TAS, GO:0005634=IEA, GO:0000122=IEA, GO:0003677=IEA, GO:0006351=IEA} cytoplasmic sequestering of transcription factor, negative regulation of cell proliferation, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding, protein dimerization activity, transcription corepressor activity Human MXRA5 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q9NR99 Matrix-remodeling-associated protein 5 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 MXRA7 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} P84157 Matrix-remodeling-associated protein 7 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 MXRA8 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9BRK3 Matrix-remodeling-associated protein 8 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 MYADM UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q96S97 Myeloid-associated differentiation marker protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 MYB InterPro UniProtKB {GO:0005515=PMID:20802522, GO:0006355=GO_REF:0000002, GO:0003700=GO_REF:0000019, GO:0048538=GO_REF:0000019, GO:0000122=PMID:20531406, GO:0048566=GO_REF:0000019, GO:0003677=GO_REF:0000002, GO:0001701=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0016363=PMID:3014652, GO:0048872=GO_REF:0000019, GO:0051574=PMID:20484083, GO:0000082=GO_REF:0000019, GO:0051571=PMID:20484083, GO:0007596=Reactome:REACT_604, GO:0045944=PMID:20531406, GO:0003682=GO_REF:0000002, GO:0030183=GO_REF:0000019, GO:0006338=PMID:20484083, GO:0045624=PMID:20484083, GO:0006816=GO_REF:0000019, GO:0045893=PMID:20531406, GO:0045892=PMID:20531406} Q708E6 C-myb v-myb myeloblastosis viral oncogene homologue (avian), exon 1 and joined CDS protein 20130413 {GO:0005515=IPI, GO:0006355=IEA, GO:0003700=IEA, GO:0048538=IEA, GO:0000122=IMP, GO:0048566=IEA, GO:0003677=IEA, GO:0001701=IEA, GO:0006351=IEA, GO:0016363=NAS, GO:0048872=IEA, GO:0051574=IMP, GO:0000082=IEA, GO:0051571=IMP, GO:0007596=TAS, GO:0045944=IMP, GO:0003682=IEA, GO:0030183=IEA, GO:0006338=IMP, GO:0045624=IMP, GO:0006816=IEA, GO:0045893=IMP, GO:0045892=IMP} B cell differentiation, G1/S transition of mitotic cell cycle, blood coagulation, calcium ion transport, chromatin remodeling, embryonic digestive tract development, homeostasis of number of cells, in utero embryonic development, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of T-helper cell differentiation, positive regulation of histone H3-K4 methylation, positive regulation of histone H3-K9 methylation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, thymus development, transcription, DNA-dependent nuclear matrix DNA binding, chromatin binding, protein binding, sequence-specific DNA binding transcription factor activity Human InterPro:IPR012642 MYBBP1A HPA UniProtKB {GO:0006355=PMID:10644447, GO:0042564=GO_REF:0000024, GO:0003887=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=PMID:21471221, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0071158=PMID:21471221, GO:0043231=GO_REF:0000052, GO:0006913=GO_REF:0000024, GO:0022904=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0005737=GO_REF:0000024, GO:0072332=PMID:21471221, GO:0042149=PMID:21471221, GO:0045892=GO_REF:0000019, GO:0008134=PMID:10644447} Q9BQG0 Myb-binding protein 1A protein 20090616 {GO:0006355=TAS, GO:0042564=ISS, GO:0003887=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA, GO:0071158=IMP, GO:0043231=IDA, GO:0006913=ISS, GO:0022904=IEA, GO:0043565=IEA, GO:0005737=ISS, GO:0072332=IMP, GO:0042149=IDA, GO:0045892=IEA, GO:0008134=TAS} cellular response to glucose starvation, intrinsic apoptotic signaling pathway by p53 class mediator, negative regulation of transcription, DNA-dependent, nucleocytoplasmic transport, positive regulation of cell cycle arrest, regulation of transcription, DNA-dependent, respiratory electron transport chain, transcription, DNA-dependent NLS-dependent protein nuclear import complex, cytoplasm, intracellular membrane-bounded organelle, nucleolus, nucleus DNA binding, DNA-directed DNA polymerase activity, sequence-specific DNA binding, transcription factor binding Human MYBL1 UniProtKB UniProtKB {GO:0006355=GO_REF:0000029, GO:0003682=GO_REF:0000002, GO:0005634=PMID:8058310, GO:0045893=PMID:8058310, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P10243 Myb-related protein A protein 20021104 {GO:0006355=NAS, GO:0003682=IEA, GO:0005634=NAS, GO:0045893=NAS, GO:0003677=IEA, GO:0006351=IEA} positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, chromatin binding Human MYBL2 Reactome UniProtKB {GO:0003700=PMID:10770937, GO:0031523=GO_REF:0000019, GO:0003682=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0090307=GO_REF:0000019, GO:0000278=Reactome:REACT_152, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P10244 Myb-related protein B protein 20130301 {GO:0003700=TAS, GO:0031523=IEA, GO:0003682=IEA, GO:0005634=IEA, GO:0090307=IEA, GO:0000278=TAS, GO:0003677=IEA, GO:0006351=IEA} mitotic cell cycle, spindle assembly involved in mitosis, transcription, DNA-dependent Myb complex, nucleus DNA binding, chromatin binding, sequence-specific DNA binding transcription factor activity Human MYBPC1 BHF-UCL UniProtKB {GO:0032982=GO_REF:0000037, GO:0030049=Reactome:REACT_16969, GO:0006936=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0030016=PMID:1429890, GO:0008307=PMID:8375400, GO:0007155=GO_REF:0000037, GO:0031432=PMID:1429890, GO:0005829=Reactome:REACT_17057} Q00872 Myosin-binding protein C, slow-type protein 20080115 {GO:0032982=IEA, GO:0030049=TAS, GO:0006936=IEA, GO:0003779=IEA, GO:0030016=ISS, GO:0008307=TAS, GO:0007155=IEA, GO:0031432=ISS, GO:0005829=TAS} cell adhesion, muscle contraction, muscle filament sliding cytosol, myofibril, myosin filament actin binding, structural constituent of muscle, titin binding Human UniProtKB:A6QP89 MYBPC2 Reactome UniProtKB {GO:0032982=GO_REF:0000037, GO:0030049=Reactome:REACT_16969, GO:0003779=GO_REF:0000037, GO:0008307=PMID:8375400, GO:0007155=GO_REF:0000037, GO:0005829=Reactome:REACT_17057} Q14324 Myosin-binding protein C, fast-type protein 20130228 {GO:0032982=IEA, GO:0030049=TAS, GO:0003779=IEA, GO:0008307=TAS, GO:0007155=IEA, GO:0005829=TAS} cell adhesion, muscle filament sliding cytosol, myosin filament actin binding, structural constituent of muscle Human MYBPC3 BHF-UCL UniProtKB {GO:0005863=GO_REF:0000024, GO:0030049=Reactome:REACT_16969, GO:0055010=PMID:16754800, GO:0006942=GO_REF:0000024, GO:0003779=GO_REF:0000037, GO:0032781=GO_REF:0000024, GO:0060048=GO_REF:0000024, GO:0030017=PMID:10024460, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_17057, GO:0031432=PMID:7493025, GO:0032971=GO_REF:0000024, GO:0003007=PMID:7493025, GO:0014705=PMID:15166115, GO:0017022=PMID:10024460, GO:0008307=PMID:7493025, GO:0007155=GO_REF:0000037, GO:0031672=PMID:10024460, GO:0001671=GO_REF:0000024, GO:0032036=PMID:17192269} Q14896 Myosin-binding protein C, cardiac-type protein 20080118 {GO:0005863=ISS, GO:0030049=TAS, GO:0055010=IMP, GO:0006942=ISS, GO:0003779=IEA, GO:0032781=ISS, GO:0060048=ISS, GO:0030017=IDA, GO:0046872=IEA, GO:0005829=TAS, GO:0031432=NAS, GO:0032971=ISS, GO:0003007=IMP, GO:0014705=NAS, GO:0017022=IDA, GO:0008307=IMP, GO:0007155=IEA, GO:0031672=IDA, GO:0001671=ISS, GO:0032036=IPI} cardiac muscle contraction, cell adhesion, heart morphogenesis, muscle filament sliding, positive regulation of ATPase activity, regulation of muscle filament sliding, regulation of striated muscle contraction, ventricular cardiac muscle tissue morphogenesis A band, C zone, cytosol, sarcomere, striated muscle myosin thick filament ATPase activator activity, actin binding, metal ion binding, myosin binding, myosin heavy chain binding, structural constituent of muscle, titin binding Human UniProtKB:P56741 MYBPH PINC UniProtKB {GO:0032982=GO_REF:0000037, GO:0006942=PMID:8486381, GO:0008307=PMID:8486381, GO:0007155=GO_REF:0000037} Q13203 Myosin-binding protein H protein 20030904 {GO:0032982=IEA, GO:0006942=TAS, GO:0008307=TAS, GO:0007155=IEA} cell adhesion, regulation of striated muscle contraction myosin filament structural constituent of muscle Human MYC BHF-UCL UniProtKB {GO:0005515=PMID:23079660, GO:0010467=Reactome:REACT_71, GO:0008284=PMID:15994933, GO:0001658=GO_REF:0000024, GO:0051276=PMID:10962037, GO:0006367=Reactome:REACT_12627, GO:0003700=PMID:9924025, GO:2000573=PMID:9924025, GO:0048147=PMID:10962037, GO:0005634=PMID:15358760, GO:0048146=PMID:9924025, GO:0032873=GO_REF:0000024, GO:0032403=PMID:18987311, GO:0006879=PMID:9924025, GO:0034644=PMID:17873522, GO:0007219=Reactome:REACT_118859, GO:0045656=PMID:9924025, GO:0000165=PMID:17873522, GO:0045944=Reactome:REACT_120734, GO:0070491=PMID:15674325, GO:0046983=GO_REF:0000002, GO:0007179=Reactome:REACT_6844, GO:0006338=PMID:21533051, GO:0060070=PMID:21533051, GO:0010332=PMID:19179467, GO:0090096=GO_REF:0000024, GO:0050679=PMID:18987311, GO:0043066=GO_REF:0000024, GO:0042493=PMID:18291362, GO:0005730=PMID:17558397, GO:0005819=GO_REF:0000019, GO:0002053=GO_REF:0000024, GO:0070888=PMID:18818310, GO:0044346=PMID:10962037, GO:0070848=PMID:18987311, GO:0003677=GO_REF:0000024, GO:0006351=Reactome:REACT_121061, GO:0006974=PMID:17873522, GO:0015671=PMID:9924025, GO:0043280=PMID:19179467, GO:0043234=PMID:17873522, GO:0006112=PMID:9924025, GO:0032204=PMID:17765874, GO:0005654=Reactome:REACT_160179, GO:0045893=PMID:17558397, GO:0008134=PMID:15674325} P01106 Myc proto-oncogene protein protein 20081208 {GO:0005515=IPI, GO:0010467=TAS, GO:0008284=IDA, GO:0001658=ISS, GO:0051276=IDA, GO:0006367=TAS, GO:0003700=IDA, GO:2000573=IMP, GO:0048147=IDA, GO:0005634=IDA, GO:0048146=IDA, GO:0032873=ISS, GO:0032403=IDA, GO:0006879=IDA, GO:0034644=IEP, GO:0007219=TAS, GO:0045656=IMP, GO:0000165=IMP, GO:0045944=TAS, GO:0070491=IPI, GO:0046983=IEA, GO:0007179=TAS, GO:0006338=IDA, GO:0060070=IDA, GO:0010332=IDA, GO:0090096=ISS, GO:0050679=IDA, GO:0043066=ISS, GO:0042493=IEP, GO:0005730=IDA, GO:0005819=IEA, GO:0002053=ISS, GO:0070888=IDA, GO:0044346=TAS, GO:0070848=TAS, GO:0003677=ISS, GO:0006351=TAS, GO:0006974=IDA, GO:0015671=NAS, GO:0043280=IDA, GO:0043234=IDA, GO:0006112=NAS, GO:0032204=IMP, GO:0005654=TAS, GO:0045893=IDA, GO:0008134=IPI} MAPK cascade, Notch signaling pathway, branching involved in ureteric bud morphogenesis, canonical Wnt receptor signaling pathway, cellular iron ion homeostasis, cellular response to UV, chromatin remodeling, chromosome organization, energy reserve metabolic process, fibroblast apoptotic process, gene expression, negative regulation of apoptotic process, negative regulation of fibroblast proliferation, negative regulation of monocyte differentiation, negative regulation of stress-activated MAPK cascade, oxygen transport, positive regulation of DNA biosynthetic process, positive regulation of cell proliferation, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of epithelial cell proliferation, positive regulation of fibroblast proliferation, positive regulation of mesenchymal cell proliferation, positive regulation of metanephric cap mesenchymal cell proliferation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of telomere maintenance, response to DNA damage stimulus, response to drug, response to gamma radiation, response to growth factor stimulus, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway nucleolus, nucleoplasm, nucleus, protein complex, spindle DNA binding, E-box binding, protein binding, protein complex binding, protein dimerization activity, repressing transcription factor binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human MYCBP HPA UniProtKB {GO:0005515=PMID:12223483, GO:0005739=GO_REF:0000039, GO:0005813=GO_REF:0000052, GO:0006355=PMID:9797456, GO:0005737=GO_REF:0000052, GO:0003713=PMID:9797456, GO:0005634=PMID:9797456, GO:0007283=PMID:12151104, GO:0006351=GO_REF:0000037} Q99417 C-Myc-binding protein protein 20111111 {GO:0005515=IPI, GO:0005739=IEA, GO:0005813=IDA, GO:0006355=IDA, GO:0005737=IDA, GO:0003713=IDA, GO:0005634=IDA, GO:0007283=IEP, GO:0006351=IEA} regulation of transcription, DNA-dependent, spermatogenesis, transcription, DNA-dependent centrosome, cytoplasm, mitochondrion, nucleus protein binding, transcription coactivator activity Human MYCBP2 UniProtKB UniProtKB {GO:0032880=GO_REF:0000019, GO:0021785=GO_REF:0000019, GO:0030424=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0004842=GO_REF:0000002, GO:0051493=GO_REF:0000019, GO:0015630=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0021952=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0042803=GO_REF:0000019, GO:0006351=GO_REF:0000037} O75592 Probable E3 ubiquitin-protein ligase MYCBP2 protein 20130413 {GO:0032880=IEA, GO:0021785=IEA, GO:0030424=IEA, GO:0006355=IEA, GO:0004842=IEA, GO:0051493=IEA, GO:0015630=IEA, GO:0005634=IEA, GO:0021952=IEA, GO:0008270=IEA, GO:0042803=IEA, GO:0006351=IEA} branchiomotor neuron axon guidance, central nervous system projection neuron axonogenesis, regulation of cytoskeleton organization, regulation of protein localization, regulation of transcription, DNA-dependent, transcription, DNA-dependent axon, microtubule cytoskeleton, nucleus protein homodimerization activity, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB-SubCell:SL-0191 MYCBPAP MGI UniProtKB {GO:0005515=PMID:12151104, GO:0005737=PMID:12151104, GO:0016020=GO_REF:0000039, GO:0007268=GO_REF:0000024, GO:0007275=GO_REF:0000037, GO:0007283=PMID:12151104, GO:0030154=GO_REF:0000037} Q8TBZ2 MYCBP-associated protein protein 20091023 {GO:0005515=IPI, GO:0005737=IDA, GO:0016020=IEA, GO:0007268=ISS, GO:0007275=IEA, GO:0007283=IEP, GO:0030154=IEA} cell differentiation, multicellular organismal development, spermatogenesis, synaptic transmission cytoplasm, membrane protein binding Human MYCL1 UniProtKB UniProtKB {GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000029, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000029, GO:0003677=PMID:10597290} P12524 Protein L-Myc-1 protein 20061106 {GO:0006355=NAS, GO:0003700=NAS, GO:0046983=IEA, GO:0005634=NAS, GO:0003677=TAS} regulation of transcription, DNA-dependent nucleus DNA binding, protein dimerization activity, sequence-specific DNA binding transcription factor activity Human MYCN IntAct UniProtKB {GO:0005515=PMID:19111882, GO:0003700=GO_REF:0000002, GO:0006357=PMID:3796607, GO:0030324=GO_REF:0000019, GO:0005634=PMID:10597290, GO:0002053=GO_REF:0000019, GO:0048704=GO_REF:0000019, GO:0003677=PMID:10597290, GO:0048712=GO_REF:0000019, GO:0001502=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0048754=GO_REF:0000019, GO:2000378=GO_REF:0000019, GO:0000785=PMID:3796607, GO:0010942=GO_REF:0000019, GO:0042733=GO_REF:0000019} P04198 N-myc proto-oncogene protein protein 20130415 {GO:0005515=IPI, GO:0003700=IEA, GO:0006357=TAS, GO:0030324=IEA, GO:0005634=IDA, GO:0002053=IEA, GO:0048704=IEA, GO:0003677=TAS, GO:0048712=IEA, GO:0001502=IEA, GO:0045944=IEA, GO:0046983=IEA, GO:0048754=IEA, GO:2000378=IEA, GO:0000785=TAS, GO:0010942=IEA, GO:0042733=IEA} branching morphogenesis of an epithelial tube, cartilage condensation, embryonic digit morphogenesis, embryonic skeletal system morphogenesis, lung development, negative regulation of astrocyte differentiation, negative regulation of reactive oxygen species metabolic process, positive regulation of cell death, positive regulation of mesenchymal cell proliferation, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter chromatin, nucleus DNA binding, protein binding, protein dimerization activity, sequence-specific DNA binding transcription factor activity Human UniProtKB:O14965 MYD88 BHF-UCL UniProtKB {GO:0032755=GO_REF:0000024, GO:0005515=PMID:21988832, GO:0016064=GO_REF:0000019, GO:0050830=GO_REF:0000019, GO:0019221=GO_REF:0000019, GO:0046330=GO_REF:0000019, GO:0045351=GO_REF:0000019, GO:0042802=PMID:21988832, GO:0002755=Reactome:REACT_27215, GO:0044130=GO_REF:0000019, GO:0043123=PMID:12761501, GO:0031663=GO_REF:0000019, GO:0038124=Reactome:REACT_8006, GO:0032760=GO_REF:0000019, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0050671=GO_REF:0000019, GO:0005121=GO_REF:0000019, GO:0014069=GO_REF:0000019, GO:0005123=PMID:9374458, GO:0002224=Reactome:REACT_9020, GO:0043234=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0034166=Reactome:REACT_9027, GO:0010008=Reactome:REACT_25392, GO:0034162=Reactome:REACT_9047, GO:0045080=GO_REF:0000019, GO:0034142=Reactome:REACT_6894, GO:0005886=Reactome:REACT_121298, GO:0002238=GO_REF:0000019, GO:0005829=Reactome:REACT_27256, GO:0051092=GO_REF:0000019, GO:0006954=GO_REF:0000037, GO:0045944=GO_REF:0000019, GO:0070555=PMID:19281832, GO:0032740=GO_REF:0000024, GO:0005149=GO_REF:0000019, GO:0043066=Reactome:REACT_13537, GO:0048011=Reactome:REACT_13776, GO:0050727=GO_REF:0000024, GO:0007254=GO_REF:0000019, GO:0070976=PMID:19509286, GO:0032747=GO_REF:0000024, GO:0009615=GO_REF:0000019, GO:0048661=GO_REF:0000019, GO:0007165=PMID:9013863, GO:0008063=GO_REF:0000019, GO:0032494=GO_REF:0000019, GO:0071260=PMID:19593445, GO:0034146=Reactome:REACT_9061, GO:0070935=PMID:15294994, GO:0007166=PMID:9374458} Q99836 Myeloid differentiation primary response protein MyD88 protein 20110127 {GO:0032755=ISS, GO:0005515=IPI, GO:0016064=IEA, GO:0050830=IEA, GO:0019221=IEA, GO:0046330=IEA, GO:0045351=IEA, GO:0042802=IPI, GO:0002755=TAS, GO:0044130=IEA, GO:0043123=IEP, GO:0031663=IEA, GO:0038124=TAS, GO:0032760=IEA, GO:0038123=TAS, GO:0034134=TAS, GO:0050671=IEA, GO:0005121=IEA, GO:0014069=IEA, GO:0005123=TAS, GO:0002224=TAS, GO:0043234=IEA, GO:0045087=TAS, GO:0034166=TAS, GO:0010008=TAS, GO:0034162=TAS, GO:0045080=IEA, GO:0034142=TAS, GO:0005886=TAS, GO:0002238=IEA, GO:0005829=TAS, GO:0051092=IEA, GO:0006954=IEA, GO:0045944=IEA, GO:0070555=IMP, GO:0032740=ISS, GO:0005149=IEA, GO:0043066=TAS, GO:0048011=TAS, GO:0050727=ISS, GO:0007254=IEA, GO:0070976=IPI, GO:0032747=ISS, GO:0009615=IEA, GO:0048661=IEA, GO:0007165=NAS, GO:0008063=IEA, GO:0032494=IEA, GO:0071260=IEP, GO:0034146=TAS, GO:0070935=IDA, GO:0007166=TAS} 3'-UTR-mediated mRNA stabilization, JNK cascade, MyD88-dependent toll-like receptor signaling pathway, Toll signaling pathway, cell surface receptor signaling pathway, cellular response to mechanical stimulus, cytokine-mediated signaling pathway, defense response to Gram-positive bacterium, immunoglobulin mediated immune response, inflammatory response, innate immune response, lipopolysaccharide-mediated signaling pathway, negative regulation of apoptotic process, negative regulation of growth of symbiont in host, neurotrophin TRK receptor signaling pathway, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of JNK cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of chemokine biosynthetic process, positive regulation of interleukin-17 production, positive regulation of interleukin-23 production, positive regulation of interleukin-6 production, positive regulation of lymphocyte proliferation, positive regulation of smooth muscle cell proliferation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of tumor necrosis factor production, regulation of inflammatory response, response to interleukin-1, response to molecule of fungal origin, response to peptidoglycan, response to virus, signal transduction, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, type I interferon biosynthetic process cytosol, endosome membrane, plasma membrane, postsynaptic density, protein complex TIR domain binding, Toll binding, death receptor binding, identical protein binding, interleukin-1 receptor binding, protein binding Human MYEF2 HPA UniProtKB {GO:0014902=PMID:8455629, GO:0005794=GO_REF:0000052, GO:0000166=GO_REF:0000002, GO:0030182=PMID:8455629, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9P2K5 Myelin expression factor 2 protein 20080818 {GO:0014902=IEP, GO:0005794=IDA, GO:0000166=IEA, GO:0030182=IEP, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} myotube differentiation, neuron differentiation, transcription, DNA-dependent Golgi apparatus, nucleolus, nucleus DNA binding, RNA binding, nucleic acid binding, nucleotide binding Human MYEOV null null {} null null null null {} null null null MYEOV2 null null {} null null null null {} null null null MYF5 BHF-UCL UniProtKB {GO:0005515=PMID:19829708, GO:0060415=GO_REF:0000019, GO:0046982=GO_REF:0000024, GO:0006357=PMID:2311584, GO:0001756=GO_REF:0000019, GO:0003705=PMID:2311584, GO:0070888=GO_REF:0000024, GO:0048704=GO_REF:0000019, GO:0042693=GO_REF:0000024, GO:0042692=Reactome:REACT_21303, GO:0051149=Reactome:REACT_21402, GO:0007517=PMID:2311584, GO:0001503=GO_REF:0000019, GO:0007519=GO_REF:0000019, GO:0030198=GO_REF:0000019, GO:0001502=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0001952=GO_REF:0000019, GO:0005654=Reactome:REACT_21369, GO:0043010=GO_REF:0000019} P13349 Myogenic factor 5 protein 20101217 {GO:0005515=IPI, GO:0060415=IEA, GO:0046982=ISS, GO:0006357=TAS, GO:0001756=IEA, GO:0003705=TAS, GO:0070888=ISS, GO:0048704=IEA, GO:0042693=ISS, GO:0042692=TAS, GO:0051149=TAS, GO:0007517=TAS, GO:0001503=IEA, GO:0007519=IEA, GO:0030198=IEA, GO:0001502=IEA, GO:0045944=IEA, GO:0001952=IEA, GO:0005654=TAS, GO:0043010=IEA} camera-type eye development, cartilage condensation, embryonic skeletal system morphogenesis, extracellular matrix organization, muscle cell differentiation, muscle cell fate commitment, muscle organ development, muscle tissue morphogenesis, ossification, positive regulation of muscle cell differentiation, positive regulation of transcription from RNA polymerase II promoter, regulation of cell-matrix adhesion, regulation of transcription from RNA polymerase II promoter, skeletal muscle tissue development, somitogenesis nucleoplasm E-box binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, protein binding, protein heterodimerization activity contributes_to Human UniProtKB:Q08856 MYF6 BHF-UCL UniProtKB {GO:0060415=GO_REF:0000019, GO:0003700=PMID:2311584, GO:0046982=GO_REF:0000024, GO:0006357=PMID:2311584, GO:0001756=GO_REF:0000019, GO:0070888=GO_REF:0000024, GO:0005634=PMID:2311584, GO:0042693=GO_REF:0000024, GO:0042692=Reactome:REACT_21303, GO:0051149=Reactome:REACT_21402, GO:0007519=PMID:2311584, GO:0045944=GO_REF:0000024, GO:0043403=GO_REF:0000019, GO:0005654=Reactome:REACT_21369, GO:0045892=GO_REF:0000019} P23409 Myogenic factor 6 protein 20101217 {GO:0060415=IEA, GO:0003700=TAS, GO:0046982=ISS, GO:0006357=TAS, GO:0001756=IEA, GO:0070888=ISS, GO:0005634=TAS, GO:0042693=ISS, GO:0042692=TAS, GO:0051149=TAS, GO:0007519=TAS, GO:0045944=ISS, GO:0043403=IEA, GO:0005654=TAS, GO:0045892=IEA} muscle cell differentiation, muscle cell fate commitment, muscle tissue morphogenesis, negative regulation of transcription, DNA-dependent, positive regulation of muscle cell differentiation, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, skeletal muscle tissue development, skeletal muscle tissue regeneration, somitogenesis nucleoplasm, nucleus E-box binding, protein heterodimerization activity, sequence-specific DNA binding transcription factor activity contributes_to Human UniProtKB:Q01795 MYH1 HPA UniProtKB {GO:0005516=GO_REF:0000037, GO:0032982=GO_REF:0000037, GO:0003774=GO_REF:0000002, GO:0014704=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003779=GO_REF:0000037, GO:0005859=PMID:18310078, GO:0005925=GO_REF:0000052, GO:0031672=GO_REF:0000019, GO:0005524=GO_REF:0000037} P12882 Myosin-1 protein 20101115 {GO:0005516=IEA, GO:0032982=IEA, GO:0003774=IEA, GO:0014704=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003779=IEA, GO:0005859=IDA, GO:0005925=IDA, GO:0031672=IEA, GO:0005524=IEA} A band, focal adhesion, intercalated disc, muscle myosin complex, myosin filament, nucleolus, nucleus ATP binding, actin binding, calmodulin binding, motor activity Human MYH10 Reactome UniProtKB {GO:0005515=PMID:7542763, GO:0005516=GO_REF:0000037, GO:0030424=GO_REF:0000019, GO:0031594=GO_REF:0000019, GO:0060041=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:0007097=GO_REF:0000019, GO:0008360=GO_REF:0000019, GO:0016459=PMID:7499478, GO:0006887=GO_REF:0000019, GO:0030898=PMID:15845534, GO:0032154=PMID:11029059, GO:0007512=GO_REF:0000019, GO:0021678=GO_REF:0000019, GO:0030426=GO_REF:0000019, GO:0006930=GO_REF:0000019, GO:0000146=PMID:15845534, GO:0005737=PMID:7699007, GO:0003774=GO_REF:0000002, GO:0051015=PMID:15845534, GO:0043197=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0021680=GO_REF:0000019, GO:0050885=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0055003=GO_REF:0000019, GO:0001778=GO_REF:0000019, GO:0016460=GO_REF:0000019, GO:0005938=PMID:7699007, GO:0030048=PMID:15845534, GO:0001725=PMID:15774463, GO:0000281=PMID:15774463, GO:0005819=GO_REF:0000019, GO:0030496=PMID:11029059, GO:0003779=PMID:7782316, GO:0001701=GO_REF:0000019, GO:0005524=PMID:15845534, GO:0043531=PMID:15845534, GO:0021670=GO_REF:0000019, GO:0021592=GO_REF:0000019, GO:0055015=GO_REF:0000019, GO:0001764=GO_REF:0000019} P35580 Myosin-10 protein 20130301 {GO:0005515=IPI, GO:0005516=IEA, GO:0030424=IEA, GO:0031594=IEA, GO:0060041=IEA, GO:0005886=IEA, GO:0008283=IEA, GO:0007097=IEA, GO:0008360=IEA, GO:0016459=NAS, GO:0006887=IEA, GO:0030898=IDA, GO:0032154=IDA, GO:0007512=IEA, GO:0021678=IEA, GO:0030426=IEA, GO:0006930=IEA, GO:0000146=IDA, GO:0005737=IDA, GO:0003774=IEA, GO:0051015=IDA, GO:0043197=IEA, GO:0007411=TAS, GO:0021680=IEA, GO:0050885=IEA, GO:0043025=IEA, GO:0055003=IEA, GO:0001778=IEA, GO:0016460=IEA, GO:0005938=IDA, GO:0030048=IDA, GO:0001725=IDA, GO:0000281=IDA, GO:0005819=IEA, GO:0030496=IDA, GO:0003779=NAS, GO:0001701=IEA, GO:0005524=IDA, GO:0043531=IDA, GO:0021670=IEA, GO:0021592=IEA, GO:0055015=IEA, GO:0001764=IEA} actin filament-based movement, adult heart development, axon guidance, cardiac myofibril assembly, cell proliferation, cerebellar Purkinje cell layer development, cytokinesis after mitosis, exocytosis, fourth ventricle development, in utero embryonic development, lateral ventricle development, neuromuscular process controlling balance, neuron migration, nuclear migration, plasma membrane repair, regulation of cell shape, retina development in camera-type eye, substrate-dependent cell migration, cell extension, third ventricle development, ventricular cardiac muscle cell development axon, cell cortex, cleavage furrow, cytoplasm, dendritic spine, growth cone, midbody, myosin II complex, myosin complex, neuromuscular junction, neuronal cell body, plasma membrane, spindle, stress fiber ADP binding, ATP binding, actin binding, actin filament binding, actin-dependent ATPase activity, calmodulin binding, microfilament motor activity, motor activity, protein binding Human MYH11 Reactome UniProtKB {GO:0005516=GO_REF:0000037, GO:0042470=GO_REF:0000039, GO:0001725=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_20663, GO:0030485=GO_REF:0000019, GO:0006939=GO_REF:0000024, GO:0048739=PMID:16444274, GO:0032982=GO_REF:0000037, GO:0003774=GO_REF:0000019, GO:0006936=Reactome:REACT_20558, GO:0007411=Reactome:REACT_18266, GO:0005859=GO_REF:0000019, GO:0030241=GO_REF:0000024, GO:0008307=PMID:16444274, GO:0048251=PMID:16444274} P35749 Myosin-11 protein 20130301 {GO:0005516=IEA, GO:0042470=IEA, GO:0001725=IEA, GO:0003779=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0030485=IEA, GO:0006939=ISS, GO:0048739=IMP, GO:0032982=IEA, GO:0003774=IEA, GO:0006936=TAS, GO:0007411=TAS, GO:0005859=IEA, GO:0030241=ISS, GO:0008307=IMP, GO:0048251=IMP} axon guidance, cardiac muscle fiber development, elastic fiber assembly, muscle contraction, skeletal muscle myosin thick filament assembly, smooth muscle contraction cytosol, melanosome, muscle myosin complex, myosin filament, smooth muscle contractile fiber, stress fiber ATP binding, actin binding, calmodulin binding, motor activity, structural constituent of muscle Human MYH13 UniProtKB UniProtKB {GO:0005516=GO_REF:0000029, GO:0000146=PMID:10388558, GO:0032982=GO_REF:0000037, GO:0006936=PMID:10388558, GO:0003779=GO_REF:0000029, GO:0005859=PMID:10388558, GO:0030016=GO_REF:0000039, GO:0005524=GO_REF:0000029, GO:0009267=GO_REF:0000019} Q9UKX3 Myosin-13 protein 20020606 {GO:0005516=NAS, GO:0000146=TAS, GO:0032982=IEA, GO:0006936=TAS, GO:0003779=NAS, GO:0005859=TAS, GO:0030016=IEA, GO:0005524=NAS, GO:0009267=IEA} cellular response to starvation, muscle contraction muscle myosin complex, myofibril, myosin filament ATP binding, actin binding, calmodulin binding, microfilament motor activity Human MYH14 Reactome UniProtKB {GO:0005516=GO_REF:0000037, GO:0003774=GO_REF:0000002, GO:0007411=Reactome:REACT_18266, GO:0008360=GO_REF:0000037, GO:0003779=GO_REF:0000037, GO:0016459=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q7Z406 Myosin-14 protein 20130301 {GO:0005516=IEA, GO:0003774=IEA, GO:0007411=TAS, GO:0008360=IEA, GO:0003779=IEA, GO:0016459=IEA, GO:0005524=IEA} axon guidance, regulation of cell shape myosin complex ATP binding, actin binding, calmodulin binding, motor activity Human MYH15 UniProtKB UniProtKB {GO:0005516=GO_REF:0000037, GO:0032982=GO_REF:0000037, GO:0003774=GO_REF:0000002, GO:0003779=GO_REF:0000037, GO:0030016=GO_REF:0000039, GO:0005524=GO_REF:0000037} Q9Y2K3 Myosin-15 protein 20130413 {GO:0005516=IEA, GO:0032982=IEA, GO:0003774=IEA, GO:0003779=IEA, GO:0030016=IEA, GO:0005524=IEA} myofibril, myosin filament ATP binding, actin binding, calmodulin binding, motor activity Human UniProtKB-SubCell:SL-0312 MYH2 HPA UniProtKB {GO:0005515=PMID:17823310, GO:0005516=GO_REF:0000029, GO:0005826=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0016459=GO_REF:0000038, GO:0030016=PMID:8145163, GO:0030017=PMID:3904738, GO:0005829=Reactome:REACT_160090, GO:0000146=PMID:10388558, GO:0003774=GO_REF:0000002, GO:0006936=PMID:8145163, GO:0001778=GO_REF:0000019, GO:0005859=PMID:3904738, GO:0008307=PMID:3904738, GO:0014823=GO_REF:0000019, GO:0005794=GO_REF:0000019, GO:0030049=PMID:3904738, GO:0005730=GO_REF:0000052, GO:0003779=GO_REF:0000029, GO:0005524=GO_REF:0000029, GO:0043234=GO_REF:0000054, GO:0032982=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0031672=GO_REF:0000019, GO:0038096=Reactome:REACT_160123, GO:0005925=GO_REF:0000052, GO:0016044=Reactome:REACT_11123} Q9UKX2 Myosin-2 protein 20101115 {GO:0005515=IPI, GO:0005516=NAS, GO:0005826=IEA, GO:0005634=IDA, GO:0016459=IEA, GO:0030016=IDA, GO:0030017=NAS, GO:0005829=TAS, GO:0000146=TAS, GO:0003774=IEA, GO:0006936=IDA, GO:0001778=IEA, GO:0005859=NAS, GO:0008307=NAS, GO:0014823=IEA, GO:0005794=IEA, GO:0030049=NAS, GO:0005730=IDA, GO:0003779=NAS, GO:0005524=NAS, GO:0043234=IDA, GO:0032982=IEA, GO:0045087=TAS, GO:0031672=IEA, GO:0038096=TAS, GO:0005925=IDA, GO:0016044=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, cellular membrane organization, innate immune response, muscle contraction, muscle filament sliding, plasma membrane repair, response to activity A band, Golgi apparatus, actomyosin contractile ring, cytosol, focal adhesion, muscle myosin complex, myofibril, myosin complex, myosin filament, nucleolus, nucleus, protein complex, sarcomere ATP binding, actin binding, calmodulin binding, microfilament motor activity, motor activity, protein binding, structural constituent of muscle Human MYH3 Reactome UniProtKB {GO:0030048=PMID:1691980, GO:0005516=GO_REF:0000037, GO:0000146=PMID:1691980, GO:0032982=GO_REF:0000037, GO:0030049=Reactome:REACT_16969, GO:0007517=PMID:2771643, GO:0003779=GO_REF:0000037, GO:0030016=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_17057} P11055 Myosin-3 protein 20130228 {GO:0030048=NAS, GO:0005516=IEA, GO:0000146=NAS, GO:0032982=IEA, GO:0030049=TAS, GO:0007517=TAS, GO:0003779=IEA, GO:0030016=IEA, GO:0005524=IEA, GO:0005829=TAS} actin filament-based movement, muscle filament sliding, muscle organ development cytosol, myofibril, myosin filament ATP binding, actin binding, calmodulin binding, microfilament motor activity Human MYH4 HPA UniProtKB {GO:0030048=PMID:10388558, GO:0005516=GO_REF:0000037, GO:0014823=GO_REF:0000019, GO:0030049=PMID:3904738, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003779=GO_REF:0000037, GO:0030016=PMID:8145163, GO:0005524=GO_REF:0000037, GO:0030017=PMID:3904738, GO:0032982=GO_REF:0000037, GO:0000146=PMID:10388558, GO:0006936=PMID:8145163, GO:0005859=PMID:3904738, GO:0008307=PMID:3904738, GO:0005925=GO_REF:0000052, GO:0016044=Reactome:REACT_11123} Q9Y623 Myosin-4 protein 20101115 {GO:0030048=NAS, GO:0005516=IEA, GO:0014823=IEA, GO:0030049=NAS, GO:0005730=IDA, GO:0005634=IDA, GO:0003779=IEA, GO:0030016=IDA, GO:0005524=IEA, GO:0030017=NAS, GO:0032982=IEA, GO:0000146=NAS, GO:0006936=IDA, GO:0005859=NAS, GO:0008307=NAS, GO:0005925=IDA, GO:0016044=TAS} actin filament-based movement, cellular membrane organization, muscle contraction, muscle filament sliding, response to activity focal adhesion, muscle myosin complex, myofibril, myosin filament, nucleolus, nucleus, sarcomere ATP binding, actin binding, calmodulin binding, microfilament motor activity, structural constituent of muscle Human MYH6 GOC UniProtKB {GO:0005516=GO_REF:0000037, GO:0030018=GO_REF:0000019, GO:0006200=PMID:15621050, GO:0055010=PMID:11815426, GO:0008016=GO_REF:0000024, GO:0006941=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0016459=PMID:12933792, GO:0060420=GO_REF:0000019, GO:0030016=GO_REF:0000024, GO:0030017=PMID:12933792, GO:0030898=PMID:16088376, GO:0007512=PMID:15998695, GO:0005829=Reactome:REACT_17057, GO:0005737=GO_REF:0000052, GO:0000146=GO_REF:0000024, GO:0006936=PMID:15621050, GO:0043462=GO_REF:0000024, GO:0030239=GO_REF:0000024, GO:0005859=PMID:1776652, GO:0008307=PMID:16088376, GO:0060070=GO_REF:0000019, GO:0016887=PMID:15621050, GO:0055009=PMID:15735645, GO:0001725=GO_REF:0000019, GO:0030049=Reactome:REACT_16969, GO:0019901=PMID:18029400, GO:0005730=GO_REF:0000052, GO:0045214=GO_REF:0000024, GO:0003779=GO_REF:0000037, GO:0030509=GO_REF:0000019, GO:0007522=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0001701=GO_REF:0000024, GO:0048739=GO_REF:0000024, GO:0032982=GO_REF:0000037, GO:0002027=PMID:15621050, GO:0002026=GO_REF:0000024, GO:0008217=GO_REF:0000024, GO:0005925=GO_REF:0000052} P13533 Myosin-6 protein 20130413 {GO:0005516=IEA, GO:0030018=IEA, GO:0006200=IDA, GO:0055010=IMP, GO:0008016=ISS, GO:0006941=ISS, GO:0005634=IDA, GO:0016459=TAS, GO:0060420=IEA, GO:0030016=ISS, GO:0030017=TAS, GO:0030898=IMP, GO:0007512=IMP, GO:0005829=TAS, GO:0005737=IDA, GO:0000146=ISS, GO:0006936=IDA, GO:0043462=ISS, GO:0030239=ISS, GO:0005859=TAS, GO:0008307=IDA, GO:0060070=IEA, GO:0016887=IDA, GO:0055009=IMP, GO:0001725=IEA, GO:0030049=TAS, GO:0019901=IPI, GO:0005730=IDA, GO:0045214=ISS, GO:0003779=IEA, GO:0030509=IEA, GO:0007522=ISS, GO:0005524=IEA, GO:0001701=ISS, GO:0048739=ISS, GO:0032982=IEA, GO:0002027=IDA, GO:0002026=ISS, GO:0008217=ISS, GO:0005925=IDA} ATP catabolic process, BMP signaling pathway, adult heart development, atrial cardiac muscle tissue morphogenesis, canonical Wnt receptor signaling pathway, cardiac muscle fiber development, in utero embryonic development, muscle contraction, muscle filament sliding, myofibril assembly, regulation of ATPase activity, regulation of blood pressure, regulation of heart contraction, regulation of heart growth, regulation of heart rate, regulation of the force of heart contraction, sarcomere organization, striated muscle contraction, ventricular cardiac muscle tissue morphogenesis, visceral muscle development Z disc, cytoplasm, cytosol, focal adhesion, muscle myosin complex, myofibril, myosin complex, myosin filament, nucleolus, nucleus, sarcomere, stress fiber ATP binding, ATPase activity, actin binding, actin-dependent ATPase activity, calmodulin binding, microfilament motor activity, protein kinase binding, structural constituent of muscle Human MYH7 HPA UniProtKB {GO:0005515=PMID:17192269, GO:0005516=GO_REF:0000037, GO:0001725=GO_REF:0000019, GO:0030018=GO_REF:0000019, GO:0030049=PMID:8514894, GO:0006200=PMID:15621050, GO:0055010=PMID:16754800, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003779=GO_REF:0000037, GO:0016459=PMID:12933792, GO:0005524=GO_REF:0000037, GO:0030898=PMID:16088376, GO:0030017=PMID:16754800, GO:0007512=PMID:15856146, GO:0005737=GO_REF:0000052, GO:0032982=PMID:19336582, GO:0000146=PMID:3021460, GO:0006936=PMID:15621050, GO:0002027=PMID:15621050, GO:0005859=PMID:3021460, GO:0008307=PMID:16088376, GO:0005925=GO_REF:0000052, GO:0016887=PMID:15621050} P12883 Myosin-7 protein 20101115 {GO:0005515=IPI, GO:0005516=IEA, GO:0001725=IEA, GO:0030018=IEA, GO:0030049=IMP, GO:0006200=IDA, GO:0055010=IMP, GO:0005730=IDA, GO:0005634=IDA, GO:0003779=IEA, GO:0016459=TAS, GO:0005524=IEA, GO:0030898=IMP, GO:0030017=TAS, GO:0007512=IMP, GO:0005737=IDA, GO:0032982=IDA, GO:0000146=NAS, GO:0006936=IDA, GO:0002027=IDA, GO:0005859=TAS, GO:0008307=IDA, GO:0005925=IDA, GO:0016887=IDA} ATP catabolic process, adult heart development, muscle contraction, muscle filament sliding, regulation of heart rate, ventricular cardiac muscle tissue morphogenesis Z disc, cytoplasm, focal adhesion, muscle myosin complex, myosin complex, myosin filament, nucleolus, nucleus, sarcomere, stress fiber ATP binding, ATPase activity, actin binding, actin-dependent ATPase activity, calmodulin binding, microfilament motor activity, protein binding, structural constituent of muscle Human MYH7B InterPro UniProtKB {GO:0032982=GO_REF:0000037, GO:0003774=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0003779=GO_REF:0000037, GO:0016459=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q5JW49 Myosin-7B protein 20130413 {GO:0032982=IEA, GO:0003774=IEA, GO:0016020=IEA, GO:0003779=IEA, GO:0016459=IEA, GO:0005524=IEA} membrane, myosin complex, myosin filament ATP binding, actin binding, motor activity Human InterPro:IPR002928 MYH8 HPA UniProtKB {GO:0005516=GO_REF:0000037, GO:0030049=Reactome:REACT_16969, GO:0005730=GO_REF:0000052, GO:0003779=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0030016=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_17057, GO:0003774=GO_REF:0000002, GO:0032982=GO_REF:0000037, GO:0006936=PMID:2715179, GO:0005859=PMID:2715179, GO:0008307=PMID:2715179, GO:0005925=GO_REF:0000052} P13535 Myosin-8 protein 20101115 {GO:0005516=IEA, GO:0030049=TAS, GO:0005730=IDA, GO:0003779=IEA, GO:0005634=IDA, GO:0030016=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0003774=IEA, GO:0032982=IEA, GO:0006936=NAS, GO:0005859=NAS, GO:0008307=NAS, GO:0005925=IDA} muscle contraction, muscle filament sliding cytosol, focal adhesion, muscle myosin complex, myofibril, myosin filament, nucleolus, nucleus ATP binding, actin binding, calmodulin binding, motor activity, structural constituent of muscle Human MYH9 UniProtKB UniProtKB {GO:0005515=PMID:16403913, GO:0005516=GO_REF:0000037, GO:0031594=GO_REF:0000019, GO:0008360=PMID:11029059, GO:0038032=GO_REF:0000002, GO:0015031=PMID:16403913, GO:0050900=PMID:12421915, GO:0042803=PMID:12237319, GO:0000910=PMID:15774463, GO:0016337=GO_REF:0000019, GO:0051015=PMID:15845534, GO:0007411=Reactome:REACT_18266, GO:0006509=PMID:16186248, GO:0007132=GO_REF:0000019, GO:0008305=PMID:10822899, GO:0031532=PMID:15869600, GO:0005819=GO_REF:0000019, GO:0007520=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0043234=PMID:12421915, GO:0043534=PMID:16403913, GO:0043531=PMID:15065866, GO:0007229=PMID:10822899, GO:0043495=PMID:16403913, GO:0005826=PMID:11029059, GO:0006200=PMID:12237319, GO:0005886=GO_REF:0000052, GO:0006928=GO_REF:0000019, GO:0005634=PMID:14508515, GO:0016459=GO_REF:0000038, GO:0015629=GO_REF:0000052, GO:0030898=PMID:15845534, GO:0032154=PMID:14508515, GO:0000212=GO_REF:0000019, GO:0005829=PMID:14508515, GO:0005737=GO_REF:0000052, GO:0003774=GO_REF:0000002, GO:0000146=PMID:15845534, GO:0005913=GO_REF:0000019, GO:0008180=PMID:18850735, GO:0030224=PMID:1912569, GO:0016460=GO_REF:0000019, GO:0016887=PMID:12237319, GO:0031252=PMID:12421915, GO:0030220=PMID:12237319, GO:0001772=PMID:15064761, GO:0030048=PMID:15845534, GO:0001725=PMID:15774463, GO:0003779=GO_REF:0000038, GO:0001525=PMID:16403913, GO:0001726=PMID:16403913, GO:0005524=GO_REF:0000038, GO:0032796=GO_REF:0000019, GO:0051295=GO_REF:0000019, GO:0000904=GO_REF:0000019, GO:0001768=GO_REF:0000019, GO:0030863=GO_REF:0000019, GO:0001931=PMID:15064761} Q5BKV1 Myosin-9 protein 20130413 {GO:0005515=IPI, GO:0005516=IEA, GO:0031594=IEA, GO:0008360=IMP, GO:0038032=IEA, GO:0015031=IMP, GO:0050900=NAS, GO:0042803=IDA, GO:0000910=IMP, GO:0016337=IEA, GO:0051015=IDA, GO:0007411=TAS, GO:0006509=IDA, GO:0007132=IEA, GO:0008305=IDA, GO:0031532=IMP, GO:0005819=IEA, GO:0007520=IEA, GO:0001701=IEA, GO:0043234=IDA, GO:0043534=IMP, GO:0043531=IDA, GO:0007229=NAS, GO:0043495=IMP, GO:0005826=IDA, GO:0006200=IDA, GO:0005886=IDA, GO:0006928=IEA, GO:0005634=IDA, GO:0016459=IEA, GO:0015629=IDA, GO:0030898=IDA, GO:0032154=IDA, GO:0000212=IEA, GO:0005829=IDA, GO:0005737=IDA, GO:0003774=IEA, GO:0000146=IDA, GO:0005913=IEA, GO:0008180=IDA, GO:0030224=IEP, GO:0016460=IEA, GO:0016887=IDA, GO:0031252=IDA, GO:0030220=IMP, GO:0001772=IDA, GO:0030048=IDA, GO:0001725=IDA, GO:0003779=IEA, GO:0001525=IDA, GO:0001726=IDA, GO:0005524=IEA, GO:0032796=IEA, GO:0051295=IEA, GO:0000904=IEA, GO:0001768=IEA, GO:0030863=IEA, GO:0001931=IDA} ATP catabolic process, actin cytoskeleton reorganization, actin filament-based movement, angiogenesis, axon guidance, blood vessel endothelial cell migration, cell morphogenesis involved in differentiation, cell-cell adhesion, cellular component movement, cytokinesis, establishment of T cell polarity, establishment of meiotic spindle localization, in utero embryonic development, integrin-mediated signaling pathway, leukocyte migration, meiotic metaphase I, meiotic spindle organization, membrane protein ectodomain proteolysis, monocyte differentiation, myoblast fusion, platelet formation, protein transport, regulation of cell shape, termination of G-protein coupled receptor signaling pathway, uropod organization actin cytoskeleton, actomyosin contractile ring, cell leading edge, cell-cell adherens junction, cleavage furrow, cortical cytoskeleton, cytoplasm, cytosol, immunological synapse, integrin complex, myosin II complex, myosin complex, neuromuscular junction, nucleus, plasma membrane, protein complex, ruffle, signalosome, spindle, stress fiber, uropod ADP binding, ATP binding, ATPase activity, actin binding, actin filament binding, actin-dependent ATPase activity, calmodulin binding, microfilament motor activity, motor activity, protein anchor, protein binding, protein homodimerization activity Human UniProtKB-KW:KW-0518 MYL1 BHF-UCL UniProtKB {GO:0006936=PMID:8145163, GO:0030049=PMID:3904738, GO:0007517=GO_REF:0000029, GO:0005509=GO_REF:0000002, GO:0005859=PMID:3904738, GO:0008307=PMID:3904738, GO:0030016=PMID:8145163, GO:0030017=PMID:3904738, GO:0060048=GO_REF:0000019, GO:0005829=Reactome:REACT_16995} P05976 Myosin light chain 1/3, skeletal muscle isoform protein 20080118 {GO:0006936=IDA, GO:0030049=NAS, GO:0007517=NAS, GO:0005509=IEA, GO:0005859=NAS, GO:0008307=NAS, GO:0030016=IDA, GO:0030017=NAS, GO:0060048=IEA, GO:0005829=TAS} cardiac muscle contraction, muscle contraction, muscle filament sliding, muscle organ development cytosol, muscle myosin complex, myofibril, sarcomere calcium ion binding, structural constituent of muscle Human MYL10 LIFEdb UniProtKB {GO:0005739=GO_REF:0000054, GO:0005509=GO_REF:0000002} Q9BUA6 Myosin regulatory light chain 10 protein 20100607 {GO:0005739=IDA, GO:0005509=IEA} mitochondrion calcium ion binding Human MYL12A ENSEMBL UniProtKB {GO:0030018=GO_REF:0000019, GO:0001725=GO_REF:0000019, GO:0072661=GO_REF:0000019, GO:0008360=GO_REF:0000019, GO:0035254=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0016460=GO_REF:0000019} P19105 Myosin regulatory light chain 12A protein 20130413 {GO:0030018=IEA, GO:0001725=IEA, GO:0072661=IEA, GO:0008360=IEA, GO:0035254=IEA, GO:0005509=IEA, GO:0016460=IEA} protein targeting to plasma membrane, regulation of cell shape Z disc, myosin II complex, stress fiber calcium ion binding, glutamate receptor binding Human Ensembl:ENSMUSP00000123412 MYL12B Reactome UniProtKB {GO:0030018=GO_REF:0000019, GO:0001725=GO_REF:0000019, GO:0006936=Reactome:REACT_20558, GO:0007411=Reactome:REACT_18266, GO:0008360=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0045177=GO_REF:0000019, GO:0016460=GO_REF:0000019, GO:0005829=Reactome:REACT_20663} O14950 Myosin regulatory light chain 12B protein 20130301 {GO:0030018=IEA, GO:0001725=IEA, GO:0006936=TAS, GO:0007411=TAS, GO:0008360=IEA, GO:0005509=IEA, GO:0045177=IEA, GO:0016460=IEA, GO:0005829=TAS} axon guidance, muscle contraction, regulation of cell shape Z disc, apical part of cell, cytosol, myosin II complex, stress fiber calcium ion binding Human MYL2 BHF-UCL UniProtKB {GO:0060047=GO_REF:0000024, GO:0030308=PMID:15824735, GO:0030049=Reactome:REACT_16969, GO:0055010=PMID:8673105, GO:0005509=PMID:11102452, GO:0006942=PMID:8673105, GO:0016459=PMID:11102452, GO:0009791=GO_REF:0000019, GO:0030016=PMID:8287067, GO:0015629=PMID:17043135, GO:0030017=PMID:16754800, GO:0060048=GO_REF:0000019, GO:0042694=GO_REF:0000019, GO:0005829=Reactome:REACT_17057, GO:0003785=PMID:9180271, GO:0048747=GO_REF:0000019, GO:0003007=GO_REF:0000019, GO:0055003=GO_REF:0000024, GO:0008307=PMID:17885681, GO:0005856=PMID:17043135, GO:0032036=PMID:8287067} P10916 Myosin regulatory light chain 2, ventricular/cardiac muscle isoform protein 20080121 {GO:0060047=ISS, GO:0030308=IMP, GO:0030049=TAS, GO:0055010=IMP, GO:0005509=IDA, GO:0006942=TAS, GO:0016459=TAS, GO:0009791=IEA, GO:0030016=NAS, GO:0015629=IDA, GO:0030017=TAS, GO:0060048=IEA, GO:0042694=IEA, GO:0005829=TAS, GO:0003785=IDA, GO:0048747=IEA, GO:0003007=IEA, GO:0055003=ISS, GO:0008307=NAS, GO:0005856=IDA, GO:0032036=NAS} cardiac muscle contraction, cardiac myofibril assembly, heart contraction, heart morphogenesis, muscle cell fate specification, muscle fiber development, muscle filament sliding, negative regulation of cell growth, post-embryonic development, regulation of striated muscle contraction, ventricular cardiac muscle tissue morphogenesis actin cytoskeleton, cytoskeleton, cytosol, myofibril, myosin complex, sarcomere actin monomer binding, calcium ion binding, myosin heavy chain binding, structural constituent of muscle Human MYL3 BHF-UCL UniProtKB {GO:0030049=Reactome:REACT_16969, GO:0055010=PMID:8673105, GO:0005509=GO_REF:0000002, GO:0006942=PMID:16675844, GO:0016459=GO_REF:0000019, GO:0032781=PMID:16675844, GO:0060048=PMID:16675844, GO:0030017=PMID:16754800, GO:0005829=Reactome:REACT_17057, GO:0003785=PMID:16675844, GO:0003774=GO_REF:0000019, GO:0002026=PMID:16675844, GO:0007519=GO_REF:0000019, GO:0032038=PMID:16675844, GO:0005859=PMID:2789520, GO:0008307=PMID:2789520, GO:0031672=PMID:16675844, GO:0031674=PMID:16675844} P08590 Myosin light chain 3 protein 20080124 {GO:0030049=TAS, GO:0055010=IMP, GO:0005509=IEA, GO:0006942=IMP, GO:0016459=IEA, GO:0032781=ISS, GO:0060048=IMP, GO:0030017=TAS, GO:0005829=TAS, GO:0003785=IDA, GO:0003774=IEA, GO:0002026=IMP, GO:0007519=IEA, GO:0032038=NAS, GO:0005859=TAS, GO:0008307=TAS, GO:0031672=IDA, GO:0031674=IDA} cardiac muscle contraction, muscle filament sliding, positive regulation of ATPase activity, regulation of striated muscle contraction, regulation of the force of heart contraction, skeletal muscle tissue development, ventricular cardiac muscle tissue morphogenesis A band, I band, cytosol, muscle myosin complex, myosin complex, sarcomere actin monomer binding, calcium ion binding, motor activity, myosin II heavy chain binding, structural constituent of muscle Human MYL4 BHF-UCL UniProtKB {GO:0030049=Reactome:REACT_16969, GO:0005509=GO_REF:0000002, GO:0032781=PMID:9738905, GO:0060048=PMID:14985854, GO:0005829=Reactome:REACT_17057, GO:0003785=PMID:9180271, GO:0007517=GO_REF:0000029, GO:0051015=PMID:9738905, GO:0002026=PMID:16675844, GO:0032038=PMID:16675844, GO:0005859=GO_REF:0000029, GO:0008307=GO_REF:0000029, GO:0031672=PMID:14985854} P12829 Myosin light chain 4 protein 20080124 {GO:0030049=TAS, GO:0005509=IEA, GO:0032781=IMP, GO:0060048=IMP, GO:0005829=TAS, GO:0003785=IDA, GO:0007517=NAS, GO:0051015=IMP, GO:0002026=IMP, GO:0032038=NAS, GO:0005859=NAS, GO:0008307=NAS, GO:0031672=IMP} cardiac muscle contraction, muscle filament sliding, muscle organ development, positive regulation of ATPase activity, regulation of the force of heart contraction A band, cytosol, muscle myosin complex actin filament binding, actin monomer binding, calcium ion binding, myosin II heavy chain binding, structural constituent of muscle Human MYL5 PINC UniProtKB {GO:0006937=PMID:1284596, GO:0005509=GO_REF:0000002, GO:0005859=PMID:1284596, GO:0008307=PMID:1284596} Q02045 Myosin light chain 5 protein 20030904 {GO:0006937=TAS, GO:0005509=IEA, GO:0005859=TAS, GO:0008307=TAS} regulation of muscle contraction muscle myosin complex calcium ion binding, structural constituent of muscle Human MYL6 BHF-UCL UniProtKB {GO:0005515=PMID:21217774, GO:0003774=PMID:2304459, GO:0016461=PMID:2304459, GO:0030049=PMID:2304459, GO:0006936=Reactome:REACT_20558, GO:0007411=Reactome:REACT_18266, GO:0007519=PMID:2304459, GO:0005509=GO_REF:0000002, GO:0016459=PMID:2304459, GO:0008307=PMID:16953301, GO:0030898=GO_REF:0000024, GO:0005829=Reactome:REACT_20663} P60660 Myosin light polypeptide 6 protein 20100810 {GO:0005515=IPI, GO:0003774=TAS, GO:0016461=TAS, GO:0030049=TAS, GO:0006936=TAS, GO:0007411=TAS, GO:0007519=TAS, GO:0005509=IEA, GO:0016459=TAS, GO:0008307=IDA, GO:0030898=ISS, GO:0005829=TAS} axon guidance, muscle contraction, muscle filament sliding, skeletal muscle tissue development cytosol, myosin complex, unconventional myosin complex actin-dependent ATPase activity, calcium ion binding, motor activity, protein binding, structural constituent of muscle Human MYL6B BHF-UCL UniProtKB {GO:0005515=PMID:15510214, GO:0003774=PMID:2304459, GO:0016461=PMID:2304459, GO:0030049=PMID:2304459, GO:0006936=Reactome:REACT_20558, GO:0007519=PMID:2304459, GO:0005509=GO_REF:0000002, GO:0016459=PMID:2304459, GO:0005859=PMID:2458299, GO:0008307=PMID:2304459, GO:0005829=Reactome:REACT_20663} P14649 Myosin light chain 6B protein 20100810 {GO:0005515=IPI, GO:0003774=TAS, GO:0016461=TAS, GO:0030049=TAS, GO:0006936=TAS, GO:0007519=TAS, GO:0005509=IEA, GO:0016459=TAS, GO:0005859=TAS, GO:0008307=TAS, GO:0005829=TAS} muscle contraction, muscle filament sliding, skeletal muscle tissue development cytosol, muscle myosin complex, myosin complex, unconventional myosin complex calcium ion binding, motor activity, protein binding, structural constituent of muscle Human MYL7 BHF-UCL UniProtKB {GO:0030048=GO_REF:0000029, GO:0006939=GO_REF:0000029, GO:0000146=GO_REF:0000029, GO:0042623=GO_REF:0000029, GO:0043197=GO_REF:0000019, GO:0005509=GO_REF:0000029, GO:0016459=PMID:1429676, GO:0031672=PMID:15621049} Q01449 Myosin regulatory light chain 2, atrial isoform protein 20080121 {GO:0030048=NAS, GO:0006939=NAS, GO:0000146=NAS, GO:0042623=NAS, GO:0043197=IEA, GO:0005509=NAS, GO:0016459=NAS, GO:0031672=IDA} actin filament-based movement, smooth muscle contraction A band, dendritic spine, myosin complex ATPase activity, coupled, calcium ion binding, microfilament motor activity Human MYL9 Reactome UniProtKB {GO:0006937=PMID:2526655, GO:0030018=GO_REF:0000019, GO:0001725=GO_REF:0000019, GO:0006936=Reactome:REACT_20558, GO:0007411=Reactome:REACT_18266, GO:0005509=GO_REF:0000002, GO:0005859=PMID:2526655, GO:0008307=PMID:2526655, GO:0005829=Reactome:REACT_20663} P24844 Myosin regulatory light polypeptide 9 protein 20130301 {GO:0006937=TAS, GO:0030018=IEA, GO:0001725=IEA, GO:0006936=TAS, GO:0007411=TAS, GO:0005509=IEA, GO:0005859=TAS, GO:0008307=TAS, GO:0005829=TAS} axon guidance, muscle contraction, regulation of muscle contraction Z disc, cytosol, muscle myosin complex, stress fiber calcium ion binding, structural constituent of muscle Human MYLIP UniProtKB UniProtKB {GO:0005515=PMID:12826659, GO:0008092=PMID:10593918, GO:0042632=GO_REF:0000019, GO:0004842=PMID:14550572, GO:0045732=GO_REF:0000019, GO:0016567=PMID:14550572, GO:0005886=GO_REF:0000039, GO:0006928=PMID:10593918, GO:0007399=PMID:10593918, GO:0005622=PMID:10593918, GO:0031648=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0032803=GO_REF:0000019, GO:0042787=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0010989=GO_REF:0000019, GO:0005856=GO_REF:0000002, GO:0019898=GO_REF:0000002} Q8WY64 E3 ubiquitin-protein ligase MYLIP protein 20050715 {GO:0005515=IPI, GO:0008092=IDA, GO:0042632=IEA, GO:0004842=IDA, GO:0045732=IEA, GO:0016567=IDA, GO:0005886=IEA, GO:0006928=IMP, GO:0007399=IMP, GO:0005622=IDA, GO:0031648=IEA, GO:0005737=IEA, GO:0032803=IEA, GO:0042787=IEA, GO:0008270=IEA, GO:0010989=IEA, GO:0005856=IEA, GO:0019898=IEA} cellular component movement, cholesterol homeostasis, negative regulation of low-density lipoprotein particle clearance, nervous system development, positive regulation of protein catabolic process, protein destabilization, protein ubiquitination, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, regulation of low-density lipoprotein particle receptor catabolic process cytoplasm, cytoskeleton, extrinsic to membrane, intracellular, plasma membrane cytoskeletal protein binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human MYLK UniProtKB UniProtKB {GO:0005515=PMID:17474147, GO:0005516=GO_REF:0000037, GO:0001725=PMID:15020676, GO:0071476=PMID:11976941, GO:0030335=PMID:19826488, GO:0005886=GO_REF:0000052, GO:0060414=PMID:21055718, GO:0014820=GO_REF:0000024, GO:0051928=PMID:16284075, GO:0090303=PMID:15825080, GO:0032060=PMID:20181817, GO:0003779=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0032154=PMID:15020676, GO:0046872=GO_REF:0000037, GO:0030027=PMID:20053363, GO:0005829=Reactome:REACT_20597, GO:0006939=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0006936=Reactome:REACT_20558, GO:0016301=GO_REF:0000038, GO:0004674=GO_REF:0000002, GO:0004687=PMID:16284075, GO:0006468=PMID:8575746} Q6P2N0 Myosin light chain kinase protein 20130413 {GO:0005515=IPI, GO:0005516=IEA, GO:0001725=IDA, GO:0071476=IDA, GO:0030335=IDA, GO:0005886=IDA, GO:0060414=IMP, GO:0014820=ISS, GO:0051928=IDA, GO:0090303=IDA, GO:0032060=IMP, GO:0003779=IEA, GO:0005524=IEA, GO:0032154=IDA, GO:0046872=IEA, GO:0030027=IDA, GO:0005829=TAS, GO:0006939=ISS, GO:0005737=IDA, GO:0006936=TAS, GO:0016301=IEA, GO:0004674=IEA, GO:0004687=IDA, GO:0006468=TAS} aorta smooth muscle tissue morphogenesis, bleb assembly, cellular hypotonic response, muscle contraction, positive regulation of calcium ion transport, positive regulation of cell migration, positive regulation of wound healing, protein phosphorylation, smooth muscle contraction, tonic smooth muscle contraction cleavage furrow, cytoplasm, cytosol, lamellipodium, plasma membrane, stress fiber ATP binding, actin binding, calmodulin binding, kinase activity, metal ion binding, myosin light chain kinase activity, protein binding, protein serine/threonine kinase activity Human UniProtKB-KW:KW-0418 MYLK2 BHF-UCL UniProtKB {GO:0005515=PMID:21556048, GO:0005516=PMID:16448786, GO:0006941=PMID:16448786, GO:0005634=PMID:21556048, GO:0007274=GO_REF:0000019, GO:0035914=PMID:21556048, GO:0060048=PMID:16448786, GO:0030017=PMID:16448786, GO:0005524=GO_REF:0000037, GO:0014816=GO_REF:0000019, GO:0032971=PMID:16448786, GO:0010628=PMID:21556048, GO:0005737=PMID:21556048, GO:0046777=PMID:21556048, GO:0018107=PMID:21556048, GO:0004687=PMID:16448786, GO:0004683=GO_REF:0000024, GO:0055007=GO_REF:0000019, GO:0055008=PMID:16448786} Q9H1R3 Myosin light chain kinase 2, skeletal/cardiac muscle protein 20080124 {GO:0005515=IPI, GO:0005516=IC, GO:0006941=IDA, GO:0005634=IDA, GO:0007274=IEA, GO:0035914=IDA, GO:0060048=IC, GO:0030017=IC, GO:0005524=IEA, GO:0014816=IEA, GO:0032971=IDA, GO:0010628=IDA, GO:0005737=IDA, GO:0046777=IDA, GO:0018107=IDA, GO:0004687=IDA, GO:0004683=ISS, GO:0055007=IEA, GO:0055008=IMP} cardiac muscle cell differentiation, cardiac muscle contraction, cardiac muscle tissue morphogenesis, neuromuscular synaptic transmission, peptidyl-threonine phosphorylation, positive regulation of gene expression, protein autophosphorylation, regulation of muscle filament sliding, satellite cell differentiation, skeletal muscle cell differentiation, striated muscle contraction cytoplasm, nucleus, sarcomere ATP binding, calmodulin binding, calmodulin-dependent protein kinase activity, myosin light chain kinase activity, protein binding Human GO:0006941 MYLK3 BHF-UCL UniProtKB {GO:0002528=PMID:18390750, GO:0045214=GO_REF:0000024, GO:0015629=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0005829=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0060298=GO_REF:0000024, GO:0071347=PMID:18390750, GO:0004687=GO_REF:0000024, GO:0055003=GO_REF:0000024, GO:0006468=GO_REF:0000024, GO:0004683=GO_REF:0000024, GO:0048769=GO_REF:0000024} Q32MK0 Myosin light chain kinase 3 protein 20101202 {GO:0002528=IMP, GO:0045214=ISS, GO:0015629=IEA, GO:0005524=IEA, GO:0005829=ISS, GO:0005737=ISS, GO:0060298=ISS, GO:0071347=IMP, GO:0004687=ISS, GO:0055003=ISS, GO:0006468=ISS, GO:0004683=ISS, GO:0048769=ISS} cardiac myofibril assembly, cellular response to interleukin-1, positive regulation of sarcomere organization, protein phosphorylation, regulation of vascular permeability involved in acute inflammatory response, sarcomere organization, sarcomerogenesis actin cytoskeleton, cytoplasm, cytosol ATP binding, calmodulin-dependent protein kinase activity, myosin light chain kinase activity Human MYLK4 UniProtKB UniProtKB {GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q86YV6 Myosin light chain kinase family member 4 protein 20130413 {GO:0004672=IEA, GO:0004674=IEA, GO:0005524=IEA} ATP binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB-KW:KW-0067 MYLPF BHF-UCL UniProtKB {GO:0006955=GO_REF:0000019, GO:0007519=GO_REF:0000024, GO:0005509=GO_REF:0000002, GO:0005859=PMID:6179945, GO:0008307=GO_REF:0000024} Q96A32 Myosin regulatory light chain 2, skeletal muscle isoform protein 20080124 {GO:0006955=IEA, GO:0007519=ISS, GO:0005509=IEA, GO:0005859=TAS, GO:0008307=ISS} immune response, skeletal muscle tissue development muscle myosin complex calcium ion binding, structural constituent of muscle Human UniProtKB:P97457 MYNN HPA UniProtKB {GO:0003700=PMID:10873615, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9NPC7 Myoneurin protein 20111111 {GO:0003700=TAS, GO:0005634=IDA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human MYO10 HPA UniProtKB {GO:0005516=GO_REF:0000037, GO:0043005=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0008360=PMID:16894163, GO:0031527=GO_REF:0000039, GO:0030175=GO_REF:0000019, GO:0016459=GO_REF:0000037, GO:0030898=GO_REF:0000024, GO:0032433=GO_REF:0000024, GO:0005829=Reactome:REACT_160257, GO:0051489=PMID:16894163, GO:0005737=GO_REF:0000052, GO:0003774=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0051015=GO_REF:0000024, GO:0007411=Reactome:REACT_18266, GO:0043025=GO_REF:0000019, GO:0060002=GO_REF:0000024, GO:0005938=GO_REF:0000039, GO:0022409=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005547=GO_REF:0000024, GO:0001726=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0030027=GO_REF:0000039, GO:0030705=GO_REF:0000024, GO:0045087=Reactome:REACT_6802, GO:0038096=Reactome:REACT_160123} Q9HD67 Unconventional myosin-X protein 20101115 {GO:0005516=IEA, GO:0043005=IEA, GO:0005886=IDA, GO:0008360=IMP, GO:0031527=IEA, GO:0030175=IEA, GO:0016459=IEA, GO:0030898=ISS, GO:0032433=ISS, GO:0005829=TAS, GO:0051489=IMP, GO:0005737=IDA, GO:0003774=IEA, GO:0005543=IEA, GO:0051015=ISS, GO:0007411=TAS, GO:0043025=IEA, GO:0060002=ISS, GO:0005938=IEA, GO:0022409=IEA, GO:0005730=IDA, GO:0005547=ISS, GO:0001726=IEA, GO:0005524=IEA, GO:0030027=IEA, GO:0030705=ISS, GO:0045087=TAS, GO:0038096=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, axon guidance, cytoskeleton-dependent intracellular transport, innate immune response, positive regulation of cell-cell adhesion, regulation of cell shape, regulation of filopodium assembly cell cortex, cytoplasm, cytosol, filopodium, filopodium membrane, filopodium tip, lamellipodium, myosin complex, neuron projection, neuronal cell body, nucleolus, plasma membrane, ruffle ATP binding, actin filament binding, actin-dependent ATPase activity, calmodulin binding, motor activity, phosphatidylinositol-3,4,5-trisphosphate binding, phospholipid binding, plus-end directed microfilament motor activity Human MYO15A UniProtKB UniProtKB {GO:0005516=GO_REF:0000037, GO:0005737=GO_REF:0000037, GO:0003774=GO_REF:0000002, GO:0042472=GO_REF:0000019, GO:0007605=GO_REF:0000019, GO:0032420=GO_REF:0000039, GO:0003779=GO_REF:0000037, GO:0007626=GO_REF:0000019, GO:0016459=GO_REF:0000037, GO:0005856=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q9UKN7 Unconventional myosin-XV protein 20130413 {GO:0005516=IEA, GO:0005737=IEA, GO:0003774=IEA, GO:0042472=IEA, GO:0007605=IEA, GO:0032420=IEA, GO:0003779=IEA, GO:0007626=IEA, GO:0016459=IEA, GO:0005856=IEA, GO:0005524=IEA} inner ear morphogenesis, locomotory behavior, sensory perception of sound cytoplasm, cytoskeleton, myosin complex, stereocilium ATP binding, actin binding, calmodulin binding, motor activity Human UniProtKB-SubCell:SL-0302 MYO16 HPA UniProtKB {GO:0048471=PMID:17029291, GO:0008285=PMID:17029291, GO:0005886=PMID:11588169, GO:0019903=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0021549=PMID:11588169, GO:0005634=GO_REF:0000052, GO:0016459=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0014065=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0045749=PMID:17029291, GO:0005829=GO_REF:0000019, GO:0003774=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0051015=PMID:11588169, GO:0048812=GO_REF:0000019, GO:0005654=PMID:17029291} Q9Y6X6 Unconventional myosin-XVI protein 20111111 {GO:0048471=IDA, GO:0008285=ISS, GO:0005886=ISS, GO:0019903=IEA, GO:0005730=IDA, GO:0021549=ISS, GO:0005634=IDA, GO:0016459=IEA, GO:0005524=IEA, GO:0014065=IEA, GO:0032403=IEA, GO:0045749=ISS, GO:0005829=IEA, GO:0003774=IEA, GO:0005737=IDA, GO:0051015=ISS, GO:0048812=IEA, GO:0005654=IDA} cerebellum development, negative regulation of S phase of mitotic cell cycle, negative regulation of cell proliferation, neuron projection morphogenesis, phosphatidylinositol 3-kinase cascade cytoplasm, cytosol, myosin complex, nucleolus, nucleoplasm, nucleus, perinuclear region of cytoplasm, plasma membrane ATP binding, actin filament binding, motor activity, protein complex binding, protein phosphatase binding Human MYO18A PINC UniProtKB {GO:0043066=PMID:9918798, GO:0005793=GO_REF:0000039, GO:0003774=GO_REF:0000002, GO:0042641=PMID:18854160, GO:0016477=PMID:18854160, GO:0031032=PMID:18854160, GO:0006259=GO_REF:0000002, GO:0016459=GO_REF:0000037, GO:0003677=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0008094=GO_REF:0000002} Q92614 Unconventional myosin-XVIIIa protein 20030904 {GO:0043066=TAS, GO:0005793=IEA, GO:0003774=IEA, GO:0042641=IDA, GO:0016477=IMP, GO:0031032=IMP, GO:0006259=IEA, GO:0016459=IEA, GO:0003677=IEA, GO:0005524=IEA, GO:0008094=IEA} DNA metabolic process, actomyosin structure organization, cell migration, negative regulation of apoptotic process actomyosin, endoplasmic reticulum-Golgi intermediate compartment, myosin complex ATP binding, DNA binding, DNA-dependent ATPase activity, motor activity Human MYO18B HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0003774=GO_REF:0000002, GO:0016461=PMID:12547197, GO:0005730=GO_REF:0000052, GO:0003779=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0016459=GO_REF:0000002, GO:0030017=GO_REF:0000039, GO:0005524=GO_REF:0000037} Q8IUG5 Unconventional myosin-XVIIIb protein 20101115 {GO:0005737=IDA, GO:0003774=IEA, GO:0016461=IDA, GO:0005730=IDA, GO:0003779=IEA, GO:0005634=IDA, GO:0016459=IEA, GO:0030017=IEA, GO:0005524=IEA} cytoplasm, myosin complex, nucleolus, nucleus, sarcomere, unconventional myosin complex ATP binding, actin binding, motor activity Human MYO19 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0003774=GO_REF:0000002, GO:0005741=GO_REF:0000039, GO:0003779=GO_REF:0000037, GO:0016459=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q96H55 Unconventional myosin-XIX protein 20100326 {GO:0005737=IDA, GO:0003774=IEA, GO:0005741=IEA, GO:0003779=IEA, GO:0016459=IEA, GO:0005524=IEA} cytoplasm, mitochondrial outer membrane, myosin complex ATP binding, actin binding, motor activity Human MYO1A UniProtKB UniProtKB {GO:0005516=GO_REF:0000037, GO:0030033=GO_REF:0000019, GO:0007605=PMID:12736868, GO:0003779=GO_REF:0000037, GO:0016459=GO_REF:0000037, GO:0016328=PMID:9858156, GO:0005524=GO_REF:0000037, GO:0005903=PMID:9858156, GO:0005902=PMID:9858156, GO:0016323=PMID:9858156, GO:0003774=GO_REF:0000002, GO:0016324=GO_REF:0000019, GO:0005737=PMID:9858156, GO:0031941=PMID:9858156, GO:0009925=GO_REF:0000019, GO:0051648=PMID:8692943, GO:0030864=PMID:8692943} Q9UBC5 Unconventional myosin-Ia protein 20061103 {GO:0005516=IEA, GO:0030033=IEA, GO:0007605=IMP, GO:0003779=IEA, GO:0016459=IEA, GO:0016328=IDA, GO:0005524=IEA, GO:0005903=IDA, GO:0005902=IDA, GO:0016323=IDA, GO:0003774=IEA, GO:0016324=IEA, GO:0005737=IDA, GO:0031941=IDA, GO:0009925=IEA, GO:0051648=IMP, GO:0030864=IDA} microvillus assembly, sensory perception of sound, vesicle localization apical plasma membrane, basal plasma membrane, basolateral plasma membrane, brush border, cortical actin cytoskeleton, cytoplasm, filamentous actin, lateral plasma membrane, microvillus, myosin complex ATP binding, actin binding, calmodulin binding, motor activity Human MYO1B UniProtKB UniProtKB {GO:0030048=GO_REF:0000024, GO:0005516=GO_REF:0000037, GO:0005886=GO_REF:0000024, GO:0005547=GO_REF:0000024, GO:0005546=GO_REF:0000024, GO:0003779=GO_REF:0000037, GO:0030175=GO_REF:0000024, GO:0016459=GO_REF:0000037, GO:0005524=GO_REF:0000024, GO:0071944=GO_REF:0000024, GO:0005903=GO_REF:0000024, GO:0000146=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0003774=GO_REF:0000002, GO:0051017=GO_REF:0000024} O43795 Unconventional myosin-Ib protein 20111027 {GO:0030048=ISS, GO:0005516=IEA, GO:0005886=ISS, GO:0005547=ISS, GO:0005546=ISS, GO:0003779=IEA, GO:0030175=ISS, GO:0016459=IEA, GO:0005524=ISS, GO:0071944=ISS, GO:0005903=ISS, GO:0000146=ISS, GO:0005737=ISS, GO:0003774=IEA, GO:0051017=ISS} actin filament bundle assembly, actin filament-based movement brush border, cell periphery, cytoplasm, filopodium, myosin complex, plasma membrane ATP binding, actin binding, calmodulin binding, microfilament motor activity, motor activity, phosphatidylinositol-3,4,5-trisphosphate binding, phosphatidylinositol-4,5-bisphosphate binding Human UniProtKB:Q05096 MYO1C Reactome UniProtKB {GO:0005516=GO_REF:0000037, GO:0060171=GO_REF:0000039, GO:2000810=PMID:21402783, GO:0005634=GO_REF:0000019, GO:0016459=GO_REF:0000002, GO:0005829=Reactome:REACT_160090, GO:0003774=GO_REF:0000002, GO:0005737=PMID:9858156, GO:0038089=PMID:23262137, GO:0016461=PMID:9119401, GO:0009925=PMID:9858156, GO:0005643=GO_REF:0000039, GO:0006810=GO_REF:0000019, GO:0001725=PMID:9858156, GO:0005730=GO_REF:0000039, GO:0005102=PMID:21402783, GO:0032420=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:1900748=PMID:23262137, GO:0008022=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0016328=PMID:9858156, GO:0005903=GO_REF:0000019, GO:0005902=PMID:9858156, GO:0031941=PMID:9858156, GO:0016020=PMID:21402783, GO:0045087=Reactome:REACT_6802, GO:0045160=GO_REF:0000019, GO:0045121=PMID:23262137, GO:0005654=GO_REF:0000039, GO:0051028=GO_REF:0000037, GO:0038096=Reactome:REACT_160123, GO:0016044=Reactome:REACT_11123} O00159 Unconventional myosin-Ic protein 20130301 {GO:0005516=IEA, GO:0060171=IEA, GO:2000810=IMP, GO:0005634=IEA, GO:0016459=IEA, GO:0005829=TAS, GO:0003774=IEA, GO:0005737=IDA, GO:0038089=IMP, GO:0016461=TAS, GO:0009925=IDA, GO:0005643=IEA, GO:0006810=IEA, GO:0001725=IDA, GO:0005730=IEA, GO:0005102=IPI, GO:0032420=IEA, GO:0003779=IEA, GO:1900748=IMP, GO:0008022=IEA, GO:0005524=IEA, GO:0016328=IDA, GO:0005903=IEA, GO:0005902=IDA, GO:0031941=IDA, GO:0016020=IDA, GO:0045087=TAS, GO:0045160=IEA, GO:0045121=IDA, GO:0005654=IEA, GO:0051028=IEA, GO:0038096=TAS, GO:0016044=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, cellular membrane organization, innate immune response, mRNA transport, positive regulation of cell migration by vascular endothelial growth factor signaling pathway, positive regulation of vascular endothelial growth factor signaling pathway, regulation of tight junction assembly, transport basal plasma membrane, brush border, cytoplasm, cytosol, filamentous actin, lateral plasma membrane, membrane, membrane raft, microvillus, myosin I complex, myosin complex, nuclear pore, nucleolus, nucleoplasm, nucleus, stereocilium, stereocilium membrane, stress fiber, unconventional myosin complex ATP binding, actin binding, calmodulin binding, motor activity, protein C-terminus binding, receptor binding Human MYO1D UniProtKB UniProtKB {GO:0005516=GO_REF:0000019, GO:0000146=GO_REF:0000019, GO:0003774=GO_REF:0000002, GO:0010923=PMID:19389623, GO:0003779=GO_REF:0000037, GO:0030673=GO_REF:0000019, GO:0016459=GO_REF:0000019, GO:0030898=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0048306=GO_REF:0000019, GO:0005790=GO_REF:0000019} O94832 Unconventional myosin-Id protein 20111103 {GO:0005516=IEA, GO:0000146=IEA, GO:0003774=IEA, GO:0010923=IDA, GO:0003779=IEA, GO:0030673=IEA, GO:0016459=IEA, GO:0030898=IEA, GO:0005524=IEA, GO:0048306=IEA, GO:0005790=IEA} negative regulation of phosphatase activity axolemma, myosin complex, smooth endoplasmic reticulum ATP binding, actin binding, actin-dependent ATPase activity, calcium-dependent protein binding, calmodulin binding, microfilament motor activity, motor activity Human MYO1E IntAct UniProtKB {GO:0005515=PMID:21458045, GO:0030048=PMID:7932763, GO:0005516=PMID:11940582, GO:0042623=PMID:11940582, GO:0072015=GO_REF:0000024, GO:0016459=PMID:11940582, GO:0015629=PMID:7932763, GO:0005524=GO_REF:0000037, GO:0001701=GO_REF:0000019, GO:0032836=GO_REF:0000024, GO:0006897=PMID:17257598, GO:0000146=PMID:7932763, GO:0005737=GO_REF:0000024, GO:0003774=PMID:7932763, GO:0045334=PMID:17257598, GO:0051015=PMID:11940582, GO:0005912=GO_REF:0000024, GO:0005911=GO_REF:0000024, GO:0003094=GO_REF:0000024, GO:0035166=GO_REF:0000019, GO:0048008=GO_REF:0000019, GO:0035091=PMID:20860408, GO:0005856=PMID:17257598, GO:0001570=GO_REF:0000019} Q12965 Unconventional myosin-Ie protein 20130415 {GO:0005515=IPI, GO:0030048=TAS, GO:0005516=IDA, GO:0042623=IDA, GO:0072015=ISS, GO:0016459=TAS, GO:0015629=TAS, GO:0005524=IEA, GO:0001701=IEA, GO:0032836=ISS, GO:0006897=IMP, GO:0000146=TAS, GO:0005737=ISS, GO:0003774=TAS, GO:0045334=IDA, GO:0051015=IDA, GO:0005912=ISS, GO:0005911=ISS, GO:0003094=ISS, GO:0035166=IEA, GO:0048008=IEA, GO:0035091=IDA, GO:0005856=IDA, GO:0001570=IEA} actin filament-based movement, endocytosis, glomerular basement membrane development, glomerular filtration, glomerular visceral epithelial cell development, in utero embryonic development, platelet-derived growth factor receptor signaling pathway, post-embryonic hemopoiesis, vasculogenesis actin cytoskeleton, adherens junction, cell-cell junction, clathrin-coated endocytic vesicle, cytoplasm, cytoskeleton, myosin complex ATP binding, ATPase activity, coupled, actin filament binding, calmodulin binding, microfilament motor activity, motor activity, phosphatidylinositol binding, protein binding Human UniProtKB:Q8N8R7 MYO1F UniProtKB UniProtKB {GO:0005516=GO_REF:0000029, GO:0030335=GO_REF:0000019, GO:0050830=GO_REF:0000019, GO:0043312=GO_REF:0000019, GO:0003779=PMID:9119401, GO:0016459=GO_REF:0000002, GO:0005524=PMID:9119401, GO:0008150=GO_REF:0000015, GO:0003774=GO_REF:0000002, GO:0007162=GO_REF:0000019, GO:0031941=GO_REF:0000019, GO:0016461=PMID:9119401, GO:0032956=GO_REF:0000019, GO:0045088=GO_REF:0000019, GO:0030864=GO_REF:0000019} O00160 Unconventional myosin-If protein 20061026 {GO:0005516=NAS, GO:0030335=IEA, GO:0050830=IEA, GO:0043312=IEA, GO:0003779=NAS, GO:0016459=IEA, GO:0005524=NAS, GO:0008150=ND, GO:0003774=IEA, GO:0007162=IEA, GO:0031941=IEA, GO:0016461=NAS, GO:0032956=IEA, GO:0045088=IEA, GO:0030864=IEA} biological_process, defense response to Gram-positive bacterium, negative regulation of cell adhesion, neutrophil degranulation, positive regulation of cell migration, regulation of actin cytoskeleton organization, regulation of innate immune response cortical actin cytoskeleton, filamentous actin, myosin complex, unconventional myosin complex ATP binding, actin binding, calmodulin binding, motor activity Human MYO1G InterPro UniProtKB {GO:0005516=GO_REF:0000037, GO:0003774=GO_REF:0000002, GO:0005886=PMID:19968988, GO:0003779=GO_REF:0000037, GO:0016459=GO_REF:0000002, GO:0005524=GO_REF:0000002} F8WEW9 Minor histocompatibility antigen HA-2 protein 20130413 {GO:0005516=IEA, GO:0003774=IEA, GO:0005886=IDA, GO:0003779=IEA, GO:0016459=IEA, GO:0005524=IEA} myosin complex, plasma membrane ATP binding, actin binding, calmodulin binding, motor activity Human InterPro:IPR001609 MYO3A UniProtKB UniProtKB {GO:0005516=PMID:12672820, GO:0007605=PMID:12032315, GO:0051491=GO_REF:0000019, GO:0016459=GO_REF:0000037, GO:0030175=PMID:17021180, GO:0032433=GO_REF:0000019, GO:0030898=PMID:12672820, GO:0003774=GO_REF:0000002, GO:0000146=PMID:1262820, GO:0005737=GO_REF:0000037, GO:0051015=GO_REF:0000019, GO:0046777=PMID:12672820, GO:0018105=GO_REF:0000019, GO:0018107=GO_REF:0000019, GO:0060002=PMID:12672820, GO:0048839=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0032426=GO_REF:0000019, GO:0001917=GO_REF:0000019, GO:0004672=PMID:12672820, GO:0031941=PMID:12672820, GO:0043531=PMID:12672820, GO:0004674=GO_REF:0000019, GO:0007601=GO_REF:0000037, GO:0050896=GO_REF:0000037} Q8NEV4 Myosin-IIIa protein 20061107 {GO:0005516=IDA, GO:0007605=IMP, GO:0051491=IEA, GO:0016459=IEA, GO:0030175=IDA, GO:0032433=IEA, GO:0030898=IDA, GO:0003774=IEA, GO:0000146=IDA, GO:0005737=IEA, GO:0051015=IEA, GO:0046777=IDA, GO:0018105=IEA, GO:0018107=IEA, GO:0060002=IDA, GO:0048839=IEA, GO:0005524=IEA, GO:0032426=IEA, GO:0001917=IEA, GO:0004672=IDA, GO:0031941=IDA, GO:0043531=IDA, GO:0004674=IEA, GO:0007601=IEA, GO:0050896=IEA} inner ear development, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, positive regulation of filopodium assembly, protein autophosphorylation, response to stimulus, sensory perception of sound, visual perception cytoplasm, filamentous actin, filopodium, filopodium tip, myosin complex, photoreceptor inner segment, stereocilium bundle tip ADP binding, ATP binding, actin filament binding, actin-dependent ATPase activity, calmodulin binding, microfilament motor activity, motor activity, plus-end directed microfilament motor activity, protein kinase activity, protein serine/threonine kinase activity Human MYO3B ENSEMBL UniProtKB {GO:0051491=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0016459=GO_REF:0000037, GO:0032433=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0032426=GO_REF:0000019, GO:0001917=GO_REF:0000019, GO:0003774=GO_REF:0000002, GO:0005737=GO_REF:0000037, GO:0000146=GO_REF:0000019, GO:0046777=GO_REF:0000019, GO:0018105=GO_REF:0000019, GO:0004674=GO_REF:0000019, GO:0018107=GO_REF:0000019, GO:0007601=GO_REF:0000037, GO:0050896=GO_REF:0000037, GO:0001750=GO_REF:0000019} Q8WXR4 Myosin-IIIb protein 20130413 {GO:0051491=IEA, GO:0003779=IEA, GO:0016459=IEA, GO:0032433=IEA, GO:0005524=IEA, GO:0032426=IEA, GO:0001917=IEA, GO:0003774=IEA, GO:0005737=IEA, GO:0000146=IEA, GO:0046777=IEA, GO:0018105=IEA, GO:0004674=IEA, GO:0018107=IEA, GO:0007601=IEA, GO:0050896=IEA, GO:0001750=IEA} peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, positive regulation of filopodium assembly, protein autophosphorylation, response to stimulus, visual perception cytoplasm, filopodium tip, myosin complex, photoreceptor inner segment, photoreceptor outer segment, stereocilium bundle tip ATP binding, actin binding, microfilament motor activity, motor activity, protein serine/threonine kinase activity Human Ensembl:ENSMUSP00000055362 MYO5A Reactome UniProtKB {GO:0005882=GO_REF:0000019, GO:0043005=PMID:10391919, GO:0005516=GO_REF:0000019, GO:0042641=GO_REF:0000019, GO:0042640=GO_REF:0000019, GO:0007268=GO_REF:0000019, GO:0035371=GO_REF:0000019, GO:0016459=GO_REF:0000019, GO:0006887=GO_REF:0000019, GO:0032402=GO_REF:0000019, GO:0030426=PMID:10391919, GO:0005737=PMID:9852149, GO:0000146=PMID:10448864, GO:0003774=GO_REF:0000002, GO:0051643=GO_REF:0000019, GO:0051015=GO_REF:0000002, GO:0042438=GO_REF:0000019, GO:0006810=PMID:11980908, GO:0043025=GO_REF:0000019, GO:0042476=GO_REF:0000019, GO:0016192=GO_REF:0000024, GO:0030048=PMID:10448864, GO:0042470=GO_REF:0000019, GO:0032869=GO_REF:0000024, GO:0017137=GO_REF:0000019, GO:0005794=GO_REF:0000019, GO:0031585=GO_REF:0000019, GO:0031987=GO_REF:0000019, GO:0042552=GO_REF:0000019, GO:0005509=GO_REF:0000019, GO:0030318=GO_REF:0000019, GO:0032252=GO_REF:0000019, GO:0003779=GO_REF:0000019, GO:0072659=GO_REF:0000024, GO:0001726=PMID:9852149, GO:0005524=GO_REF:0000037, GO:0050808=GO_REF:0000019, GO:0032593=GO_REF:0000024, GO:0042759=GO_REF:0000019, GO:0044267=Reactome:REACT_17015, GO:0007601=GO_REF:0000019, GO:0030073=GO_REF:0000019, GO:0016044=Reactome:REACT_11123, GO:0001750=GO_REF:0000019} Q9Y4I1 Unconventional myosin-Va protein 20130301 {GO:0005882=IEA, GO:0043005=NAS, GO:0005516=IEA, GO:0042641=IEA, GO:0042640=IEA, GO:0007268=IEA, GO:0035371=IEA, GO:0016459=IEA, GO:0006887=IEA, GO:0032402=IEA, GO:0030426=NAS, GO:0005737=IDA, GO:0000146=NAS, GO:0003774=IEA, GO:0051643=IEA, GO:0051015=IEA, GO:0042438=IEA, GO:0006810=NAS, GO:0043025=IEA, GO:0042476=IEA, GO:0016192=ISS, GO:0030048=NAS, GO:0042470=IEA, GO:0032869=ISS, GO:0017137=IEA, GO:0005794=IEA, GO:0031585=IEA, GO:0031987=IEA, GO:0042552=IEA, GO:0005509=IEA, GO:0030318=IEA, GO:0032252=IEA, GO:0003779=IEA, GO:0072659=ISS, GO:0001726=IDA, GO:0005524=IEA, GO:0050808=IEA, GO:0032593=ISS, GO:0042759=IEA, GO:0044267=TAS, GO:0007601=IEA, GO:0030073=IEA, GO:0016044=TAS, GO:0001750=IEA} actin filament-based movement, anagen, cellular membrane organization, cellular protein metabolic process, cellular response to insulin stimulus, endoplasmic reticulum localization, exocytosis, insulin secretion, locomotion involved in locomotory behavior, long-chain fatty acid biosynthetic process, melanin biosynthetic process, melanocyte differentiation, melanosome transport, myelination, odontogenesis, protein localization to plasma membrane, regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity, secretory granule localization, synapse organization, synaptic transmission, transport, vesicle-mediated transport, visual perception Golgi apparatus, actomyosin, cytoplasm, growth cone, insulin-responsive compartment, intermediate filament, melanosome, microtubule plus end, myosin complex, neuron projection, neuronal cell body, photoreceptor outer segment, ruffle ATP binding, Rab GTPase binding, actin binding, actin filament binding, calcium ion binding, calmodulin binding, microfilament motor activity, motor activity Human MYO5B Reactome UniProtKB {GO:0005515=PMID:19542231, GO:0005516=GO_REF:0000037, GO:0017137=PMID:17462998, GO:0003779=GO_REF:0000037, GO:0016459=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0043234=PMID:17462998, GO:0000146=Reactome:REACT_23863, GO:0006833=Reactome:REACT_24023, GO:0016192=PMID:17462998, GO:0030659=Reactome:REACT_23863} Q9ULV0 Unconventional myosin-Vb protein 20111231 {GO:0005515=IPI, GO:0005516=IEA, GO:0017137=IPI, GO:0003779=IEA, GO:0016459=IEA, GO:0015031=IEA, GO:0005524=IEA, GO:0055085=TAS, GO:0043234=IDA, GO:0000146=TAS, GO:0006833=TAS, GO:0016192=IMP, GO:0030659=TAS} protein transport, transmembrane transport, vesicle-mediated transport, water transport cytoplasmic vesicle membrane, myosin complex, protein complex ATP binding, Rab GTPase binding, actin binding, calmodulin binding, microfilament motor activity, protein binding Human MYO5C UniProtKB UniProtKB {GO:0005516=GO_REF:0000037, GO:0003774=GO_REF:0000002, GO:0051015=GO_REF:0000002, GO:0003779=GO_REF:0000037, GO:0016459=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q9NQX4 Unconventional myosin-Vc protein 20130413 {GO:0005516=IEA, GO:0003774=IEA, GO:0051015=IEA, GO:0003779=IEA, GO:0016459=IEA, GO:0005524=IEA} myosin complex ATP binding, actin binding, actin filament binding, calmodulin binding, motor activity Human UniProtKB-KW:KW-0518 MYO6 IntAct UniProtKB {GO:0005515=PMID:22323290, GO:0005516=GO_REF:0000024, GO:0007605=GO_REF:0000019, GO:0006605=GO_REF:0000019, GO:0005765=Reactome:REACT_10083, GO:0006886=GO_REF:0000024, GO:0071257=GO_REF:0000019, GO:0051015=PMID:9852149, GO:0048167=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0060001=PMID:10519557, GO:0005938=GO_REF:0000024, GO:0031965=PMID:16507995, GO:0005794=PMID:16507995, GO:0042472=GO_REF:0000019, GO:0030330=PMID:16507995, GO:0007416=GO_REF:0000019, GO:0016358=GO_REF:0000019, GO:0006897=PMID:15247260, GO:0043531=GO_REF:0000024, GO:0016591=PMID:16949370, GO:0005654=PMID:16948370, GO:0016044=Reactome:REACT_11123, GO:0030424=GO_REF:0000019, GO:0048471=PMID:9852149, GO:0051046=PMID:15837803, GO:0005886=Reactome:REACT_18393, GO:0007268=Reactome:REACT_13685, GO:0005634=PMID:16507995, GO:0030139=GO_REF:0000024, GO:0016459=GO_REF:0000038, GO:0005829=Reactome:REACT_18393, GO:0003774=GO_REF:0000024, GO:0005737=PMID:9852149, GO:0016461=PMID:9259267, GO:0045944=PMID:16949370, GO:0007626=GO_REF:0000019, GO:0030048=GO_REF:0000024, GO:0042491=GO_REF:0000019, GO:0003779=PMID:10519557, GO:0032587=GO_REF:0000039, GO:0001726=PMID:9852149, GO:0005524=GO_REF:0000037, GO:0014047=GO_REF:0000019, GO:0030665=GO_REF:0000039, GO:0005905=GO_REF:0000039, GO:0045334=PMID:11447109, GO:0031941=PMID:9852149, GO:0016023=PMID:16507995} Q9UM54 Unconventional myosin-VI protein 20130415 {GO:0005515=IPI, GO:0005516=ISS, GO:0007605=IEA, GO:0006605=IEA, GO:0005765=TAS, GO:0006886=ISS, GO:0071257=IEA, GO:0051015=IDA, GO:0048167=IEA, GO:0043025=IEA, GO:0060001=NAS, GO:0005938=ISS, GO:0031965=IDA, GO:0005794=IDA, GO:0042472=IEA, GO:0030330=IDA, GO:0007416=IEA, GO:0016358=IEA, GO:0006897=IMP, GO:0043531=ISS, GO:0016591=IDA, GO:0005654=IDA, GO:0016044=TAS, GO:0030424=IEA, GO:0048471=IDA, GO:0051046=IMP, GO:0005886=TAS, GO:0007268=TAS, GO:0005634=IDA, GO:0030139=ISS, GO:0016459=IEA, GO:0005829=TAS, GO:0003774=ISS, GO:0005737=IDA, GO:0016461=TAS, GO:0045944=IMP, GO:0007626=IEA, GO:0030048=ISS, GO:0042491=IEA, GO:0003779=TAS, GO:0032587=IEA, GO:0001726=IDA, GO:0005524=IEA, GO:0014047=IEA, GO:0030665=IEA, GO:0005905=IEA, GO:0045334=IDA, GO:0031941=IDA, GO:0016023=IDA} DNA damage response, signal transduction by p53 class mediator, actin filament-based movement, auditory receptor cell differentiation, cellular membrane organization, cellular response to electrical stimulus, dendrite development, endocytosis, glutamate secretion, inner ear morphogenesis, intracellular protein transport, locomotory behavior, positive regulation of transcription from RNA polymerase II promoter, protein targeting, regulation of secretion, regulation of synaptic plasticity, sensory perception of sound, synapse assembly, synaptic transmission DNA-directed RNA polymerase II, holoenzyme, Golgi apparatus, axon, cell cortex, clathrin-coated endocytic vesicle, clathrin-coated vesicle membrane, coated pit, cytoplasm, cytoplasmic membrane-bounded vesicle, cytosol, endocytic vesicle, filamentous actin, lysosomal membrane, myosin complex, neuronal cell body, nuclear membrane, nucleoplasm, nucleus, perinuclear region of cytoplasm, plasma membrane, ruffle, ruffle membrane, unconventional myosin complex ADP binding, ATP binding, actin binding, actin filament binding, calmodulin binding, minus-end directed microfilament motor activity, motor activity, protein binding Human UniProtKB:P98078 MYO7A HGNC UniProtKB {GO:0005515=PMID:23023331, GO:0005516=PMID:15300860, GO:0007605=PMID:11398101, GO:0060088=GO_REF:0000019, GO:0045202=PMID:8842737, GO:0016459=GO_REF:0000037, GO:0005765=PMID:16001398, GO:0006886=GO_REF:0000019, GO:0005829=PMID:15300860, GO:0000146=PMID:21687988, GO:0016324=GO_REF:0000019, GO:0003774=GO_REF:0000002, GO:0051015=PMID:21687988, GO:0051904=GO_REF:0000019, GO:0046983=PMID:8622919, GO:0005856=GO_REF:0000002, GO:0005938=GO_REF:0000039, GO:0030048=PMID:21687988, GO:0042470=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0048563=GO_REF:0000019, GO:0032420=GO_REF:0000019, GO:0001845=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0001917=PMID:8842737, GO:0032391=GO_REF:0000019, GO:0050957=PMID:7870171, GO:0007601=PMID:7870171, GO:0042462=PMID:8842737, GO:0007040=PMID:16001398, GO:0050953=PMID:11398101, GO:0001750=PMID:8842737} Q13402 Unconventional myosin-VIIa protein 20070807 {GO:0005515=IPI, GO:0005516=IMP, GO:0007605=IMP, GO:0060088=IEA, GO:0045202=IDA, GO:0016459=IEA, GO:0005765=IDA, GO:0006886=IEA, GO:0005829=IDA, GO:0000146=IDA, GO:0016324=IEA, GO:0003774=IEA, GO:0051015=IDA, GO:0051904=IEA, GO:0046983=RCA, GO:0005856=IEA, GO:0005938=IEA, GO:0030048=IDA, GO:0042470=IEA, GO:0019904=IEA, GO:0048563=IEA, GO:0032420=IEA, GO:0001845=IEA, GO:0005524=IEA, GO:0001917=IDA, GO:0032391=IEA, GO:0050957=IMP, GO:0007601=IMP, GO:0042462=IC, GO:0007040=IDA, GO:0050953=IMP, GO:0001750=IDA} actin filament-based movement, auditory receptor cell stereocilium organization, equilibrioception, eye photoreceptor cell development, intracellular protein transport, lysosome organization, phagolysosome assembly, pigment granule transport, post-embryonic organ morphogenesis, sensory perception of light stimulus, sensory perception of sound, visual perception apical plasma membrane, cell cortex, cytoskeleton, cytosol, lysosomal membrane, melanosome, myosin complex, photoreceptor connecting cilium, photoreceptor inner segment, photoreceptor outer segment, stereocilium, synapse ATP binding, actin filament binding, calmodulin binding, microfilament motor activity, motor activity, protein binding, protein dimerization activity, protein domain specific binding Human MYO7B UniProtKB UniProtKB {GO:0016324=GO_REF:0000039, GO:0003774=GO_REF:0000002, GO:0003779=GO_REF:0000037, GO:0016459=GO_REF:0000037, GO:0005856=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q6PIF6 Unconventional myosin-VIIb protein 20130413 {GO:0016324=IEA, GO:0003774=IEA, GO:0003779=IEA, GO:0016459=IEA, GO:0005856=IEA, GO:0005524=IEA} apical plasma membrane, cytoskeleton, myosin complex ATP binding, actin binding, motor activity Human UniProtKB-SubCell:SL-0015 MYO9A UniProtKB UniProtKB {GO:0005515=PMID:15644318, GO:0051056=Reactome:REACT_11051, GO:0007264=Reactome:REACT_11044, GO:0003779=GO_REF:0000037, GO:0016459=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0046872=GO_REF:0000038, GO:0005829=Reactome:REACT_9982, GO:0035556=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0003774=GO_REF:0000002, GO:0016461=PMID:8022818, GO:0016021=GO_REF:0000037, GO:0007601=PMID:10409426, GO:0005096=GO_REF:0000037} H3BV44 Unconventional myosin-IXa protein 20130413 {GO:0005515=IPI, GO:0051056=TAS, GO:0007264=TAS, GO:0003779=IEA, GO:0016459=IEA, GO:0005524=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0035556=IEA, GO:0005622=IEA, GO:0007165=IEA, GO:0003774=IEA, GO:0016461=NAS, GO:0016021=IEA, GO:0007601=TAS, GO:0005096=IEA} intracellular signal transduction, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction, visual perception cytosol, integral to membrane, intracellular, myosin complex, unconventional myosin complex ATP binding, GTPase activator activity, actin binding, metal ion binding, motor activity, protein binding Human UniProtKB-KW:KW-0479 MYO9B GOC UniProtKB {GO:0005515=PMID:16417406, GO:0005516=PMID:9490638, GO:0048471=PMID:8907710, GO:0006200=PMID:16338935, GO:0007264=Reactome:REACT_11044, GO:0016459=GO_REF:0000037, GO:0007266=PMID:9490638, GO:0015629=PMID:8907710, GO:0046872=GO_REF:0000037, GO:0042803=PMID:11901422, GO:0005829=Reactome:REACT_9982, GO:0035556=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0003774=GO_REF:0000002, GO:0005737=PMID:8907710, GO:0000146=PMID:16616011, GO:0032011=PMID:15644318, GO:0016887=PMID:16338935, GO:0005938=PMID:8907710, GO:0030048=PMID:8907710, GO:0051056=Reactome:REACT_11051, GO:0003779=PMID:9490638, GO:0005524=PMID:16338935, GO:0005100=PMID:9490638, GO:0007165=GO_REF:0000002, GO:0031941=PMID:8907710, GO:0043531=PMID:16338935, GO:0032321=PMID:9490638} Q13459 Unconventional myosin-IXb protein 20130413 {GO:0005515=IPI, GO:0005516=IDA, GO:0048471=IDA, GO:0006200=IDA, GO:0007264=TAS, GO:0016459=IEA, GO:0007266=IC, GO:0015629=TAS, GO:0046872=IEA, GO:0042803=IDA, GO:0005829=TAS, GO:0035556=IEA, GO:0005622=IEA, GO:0003774=IEA, GO:0005737=IDA, GO:0000146=IDA, GO:0032011=IDA, GO:0016887=IDA, GO:0005938=IDA, GO:0030048=TAS, GO:0051056=TAS, GO:0003779=IDA, GO:0005524=IDA, GO:0005100=IDA, GO:0007165=IEA, GO:0031941=IDA, GO:0043531=IDA, GO:0032321=IDA} ARF protein signal transduction, ATP catabolic process, Rho protein signal transduction, actin filament-based movement, intracellular signal transduction, positive regulation of Rho GTPase activity, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction actin cytoskeleton, cell cortex, cytoplasm, cytosol, filamentous actin, intracellular, myosin complex, perinuclear region of cytoplasm ADP binding, ATP binding, ATPase activity, Rho GTPase activator activity, actin binding, calmodulin binding, metal ion binding, microfilament motor activity, motor activity, protein binding, protein homodimerization activity Human MYOC MGI UniProtKB {GO:0005791=GO_REF:0000039, GO:0005929=GO_REF:0000039, GO:0005198=PMID:9169133, GO:0005615=PMID:17317787, GO:0009653=PMID:9169133} Q99972 Myocilin protein 20070615 {GO:0005791=IEA, GO:0005929=IEA, GO:0005198=TAS, GO:0005615=IDA, GO:0009653=TAS} anatomical structure morphogenesis cilium, extracellular space, rough endoplasmic reticulum structural molecule activity Human MYOCD BHF-UCL UniProtKB {GO:0005515=PMID:14970199, GO:0060065=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0008285=PMID:18451334, GO:0042826=GO_REF:0000019, GO:0045736=PMID:18451334, GO:0055012=GO_REF:0000019, GO:0005634=PMID:14970199, GO:0035065=GO_REF:0000024, GO:0010832=GO_REF:0000019, GO:1900222=PMID:19098903, GO:0045661=GO_REF:0000019, GO:0045987=PMID:17215356, GO:0001560=GO_REF:0000019, GO:0045944=PMID:14970199, GO:0051152=PMID:18451334, GO:0061049=GO_REF:0000019, GO:2001015=PMID:18451334, GO:0010667=GO_REF:0000019, GO:0097070=GO_REF:0000019, GO:0055007=GO_REF:0000024, GO:0030511=GO_REF:0000019, GO:0035035=GO_REF:0000019, GO:0001666=PMID:19098903, GO:0051150=PMID:17215356, GO:0048286=GO_REF:0000019, GO:2000721=PMID:15907818, GO:0003713=GO_REF:0000019, GO:0071456=GO_REF:0000019, GO:0048565=GO_REF:0000019, GO:0070412=GO_REF:0000019, GO:2000724=GO_REF:0000024, GO:0000122=GO_REF:0000019, GO:0035051=PMID:12640126, GO:2000727=PMID:18451334, GO:0001077=PMID:22157009, GO:0001076=GO_REF:0000024, GO:0071363=GO_REF:0000019, GO:0043388=GO_REF:0000019, GO:0060157=GO_REF:0000019, GO:0035733=GO_REF:0000019, GO:0001570=GO_REF:0000019, GO:0003257=PMID:15907818, GO:0003231=GO_REF:0000019, GO:0051145=PMID:14970199, GO:0008134=PMID:16054032} Q8IZQ8 Myocardin protein 20110608 {GO:0005515=IPI, GO:0060065=IEA, GO:0008284=IEA, GO:0008285=IDA, GO:0042826=IEA, GO:0045736=IDA, GO:0055012=IEA, GO:0005634=IDA, GO:0035065=ISS, GO:0010832=IEA, GO:1900222=IMP, GO:0045661=IEA, GO:0045987=IDA, GO:0001560=IEA, GO:0045944=IDA, GO:0051152=IDA, GO:0061049=IEA, GO:2001015=IDA, GO:0010667=IEA, GO:0097070=IEA, GO:0055007=ISS, GO:0030511=IEA, GO:0035035=IEA, GO:0001666=IEP, GO:0051150=TAS, GO:0048286=IEA, GO:2000721=IDA, GO:0003713=IEA, GO:0071456=IEA, GO:0048565=IEA, GO:0070412=IEA, GO:2000724=ISS, GO:0000122=IEA, GO:0035051=NAS, GO:2000727=IDA, GO:0001077=IDA, GO:0001076=ISS, GO:0071363=IEA, GO:0043388=IEA, GO:0060157=IEA, GO:0035733=IEA, GO:0001570=IEA, GO:0003257=IDA, GO:0003231=IEA, GO:0051145=IMP, GO:0008134=IPI} cardiac muscle cell differentiation, cardiac ventricle development, cardiocyte differentiation, cell growth involved in cardiac muscle cell development, cellular response to growth factor stimulus, cellular response to hypoxia, digestive tract development, ductus arteriosus closure, hepatic stellate cell activation, lung alveolus development, negative regulation of beta-amyloid clearance, negative regulation of cardiac muscle cell apoptotic process, negative regulation of cell proliferation, negative regulation of cyclin-dependent protein serine/threonine kinase activity, negative regulation of myotube differentiation, negative regulation of skeletal muscle cell differentiation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of DNA binding, positive regulation of cardiac muscle cell differentiation, positive regulation of cardiac vascular smooth muscle cell differentiation, positive regulation of cell proliferation, positive regulation of smooth muscle cell differentiation, positive regulation of smooth muscle contraction, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation, positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation, positive regulation of transforming growth factor beta receptor signaling pathway, regulation of cell growth by extracellular stimulus, regulation of histone acetylation, regulation of myoblast differentiation, regulation of smooth muscle cell differentiation, response to hypoxia, smooth muscle cell differentiation, urinary bladder development, uterus development, vasculogenesis, ventricular cardiac muscle cell differentiation nucleus R-SMAD binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II transcription factor binding transcription factor activity, histone acetyltransferase binding, histone deacetylase binding, protein binding, transcription coactivator activity, transcription factor binding Human MYOD1 BHF-UCL UniProtKB {GO:0005515=PMID:10915743, GO:0000790=GO_REF:0000024, GO:0003705=PMID:1846704, GO:0005634=PMID:3175662, GO:0030016=GO_REF:0000019, GO:0042693=GO_REF:0000024, GO:0042692=Reactome:REACT_21303, GO:0000381=GO_REF:0000019, GO:0045944=GO_REF:0000024, GO:0043503=GO_REF:0000019, GO:0055007=GO_REF:0000019, GO:0031625=GO_REF:0000019, GO:0009267=GO_REF:0000019, GO:0005667=GO_REF:0000024, GO:0046982=GO_REF:0000024, GO:0006357=PMID:1846704, GO:0071453=GO_REF:0000019, GO:0003713=PMID:1846704, GO:0014908=GO_REF:0000019, GO:1901741=PMID:10672515, GO:0048741=GO_REF:0000019, GO:0070888=GO_REF:0000024, GO:0014904=PMID:10672515, GO:0071385=GO_REF:0000019, GO:0007518=GO_REF:0000019, GO:0007517=PMID:1846704, GO:0051149=PMID:10672515, GO:0007519=PMID:3175662, GO:0043415=GO_REF:0000019, GO:0006468=PMID:3175662, GO:0005654=Reactome:REACT_21369, GO:0008134=GO_REF:0000019} P15172 Myoblast determination protein 1 protein 20110126 {GO:0005515=IPI, GO:0000790=ISS, GO:0003705=TAS, GO:0005634=TAS, GO:0030016=IEA, GO:0042693=ISS, GO:0042692=TAS, GO:0000381=IEA, GO:0045944=ISS, GO:0043503=IEA, GO:0055007=IEA, GO:0031625=IEA, GO:0009267=IEA, GO:0005667=ISS, GO:0046982=ISS, GO:0006357=TAS, GO:0071453=IEA, GO:0003713=TAS, GO:0014908=IEA, GO:1901741=IDA, GO:0048741=IEA, GO:0070888=ISS, GO:0014904=IDA, GO:0071385=IEA, GO:0007518=IEA, GO:0007517=TAS, GO:0051149=IDA, GO:0007519=TAS, GO:0043415=IEA, GO:0006468=TAS, GO:0005654=TAS, GO:0008134=IEA} cardiac muscle cell differentiation, cellular response to glucocorticoid stimulus, cellular response to oxygen levels, cellular response to starvation, muscle cell differentiation, muscle cell fate commitment, muscle organ development, myoblast fate determination, myotube cell development, myotube differentiation involved in skeletal muscle regeneration, positive regulation of muscle cell differentiation, positive regulation of myoblast fusion, positive regulation of skeletal muscle tissue regeneration, positive regulation of transcription from RNA polymerase II promoter, protein phosphorylation, regulation of alternative mRNA splicing, via spliceosome, regulation of transcription from RNA polymerase II promoter, skeletal muscle fiber adaptation, skeletal muscle fiber development, skeletal muscle tissue development myofibril, nuclear chromatin, nucleoplasm, nucleus, transcription factor complex E-box binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, protein binding, protein heterodimerization activity, transcription coactivator activity, transcription factor binding, ubiquitin protein ligase binding Human UniProtKB:P10085 MYOF HPA UniProtKB {GO:0031965=GO_REF:0000039, GO:0030947=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0008015=PMID:10607832, GO:0005635=PMID:10607832, GO:0031410=PMID:11959863, GO:0043231=GO_REF:0000052, GO:0034605=GO_REF:0000019, GO:0005543=GO_REF:0000024, GO:0006936=PMID:10607832, GO:0005901=GO_REF:0000024, GO:0001778=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0030659=GO_REF:0000039} Q9NZM1 Myoferlin protein 20101115 {GO:0031965=IEA, GO:0030947=IEA, GO:0005886=IDA, GO:0008015=TAS, GO:0005635=TAS, GO:0031410=IDA, GO:0043231=IDA, GO:0034605=IEA, GO:0005543=ISS, GO:0006936=TAS, GO:0005901=ISS, GO:0001778=ISS, GO:0016021=IEA, GO:0030659=IEA} blood circulation, cellular response to heat, muscle contraction, plasma membrane repair, regulation of vascular endothelial growth factor receptor signaling pathway caveola, cytoplasmic vesicle, cytoplasmic vesicle membrane, integral to membrane, intracellular membrane-bounded organelle, nuclear envelope, nuclear membrane, plasma membrane phospholipid binding Human MYOG BHF-UCL UniProtKB {GO:0000987=GO_REF:0000019, GO:0071285=GO_REF:0000019, GO:0005667=GO_REF:0000024, GO:0003700=PMID:1850513, GO:0000977=GO_REF:0000024, GO:0046982=GO_REF:0000024, GO:0048741=GO_REF:0000019, GO:0070888=GO_REF:0000024, GO:0001228=PMID:19783823, GO:0042693=GO_REF:0000024, GO:0042692=Reactome:REACT_21303, GO:0051149=Reactome:REACT_21402, GO:0001503=GO_REF:0000019, GO:0071363=GO_REF:0000019, GO:0007519=PMID:10329008, GO:0045944=GO_REF:0000024, GO:0005654=Reactome:REACT_21369, GO:0042789=PMID:19783823} P15173 Myogenin protein 20101217 {GO:0000987=IEA, GO:0071285=IEA, GO:0005667=ISS, GO:0003700=TAS, GO:0000977=ISS, GO:0046982=ISS, GO:0048741=IEA, GO:0070888=ISS, GO:0001228=TAS, GO:0042693=ISS, GO:0042692=TAS, GO:0051149=TAS, GO:0001503=IEA, GO:0071363=IEA, GO:0007519=TAS, GO:0045944=ISS, GO:0005654=TAS, GO:0042789=TAS} cellular response to growth factor stimulus, cellular response to lithium ion, mRNA transcription from RNA polymerase II promoter, muscle cell differentiation, muscle cell fate commitment, ossification, positive regulation of muscle cell differentiation, positive regulation of transcription from RNA polymerase II promoter, skeletal muscle fiber development, skeletal muscle tissue development nucleoplasm, transcription factor complex E-box binding, RNA polymerase II regulatory region sequence-specific DNA binding, RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, core promoter proximal region sequence-specific DNA binding, protein heterodimerization activity, sequence-specific DNA binding transcription factor activity Human UniProtKB:P17920 MYOM1 PINC UniProtKB {GO:0005863=PMID:6537951, GO:0006936=GO_REF:0000019, GO:0008307=PMID:7505783, GO:0031430=GO_REF:0000024, GO:0042803=GO_REF:0000024} P52179 Myomesin-1 protein 20030904 {GO:0005863=TAS, GO:0006936=IEA, GO:0008307=TAS, GO:0031430=ISS, GO:0042803=ISS} muscle contraction M band, striated muscle myosin thick filament protein homodimerization activity, structural constituent of muscle Human MYOM2 PINC UniProtKB {GO:0032982=GO_REF:0000037, GO:0006936=GO_REF:0000019, GO:0008307=PMID:7505783, GO:0031430=GO_REF:0000039} P54296 Myomesin-2 protein 20030904 {GO:0032982=IEA, GO:0006936=IEA, GO:0008307=TAS, GO:0031430=IEA} muscle contraction M band, myosin filament structural constituent of muscle Human MYOT IntAct UniProtKB {GO:0005515=PMID:11038172, GO:0042383=GO_REF:0000039, GO:0030018=GO_REF:0000039, GO:0006936=PMID:10958653, GO:0003779=GO_REF:0000037, GO:0015629=PMID:10369880, GO:0008307=PMID:10958653} Q9UBF9 Myotilin protein 20130415 {GO:0005515=IPI, GO:0042383=IEA, GO:0030018=IEA, GO:0006936=TAS, GO:0003779=IEA, GO:0015629=TAS, GO:0008307=TAS} muscle contraction Z disc, actin cytoskeleton, sarcolemma actin binding, protein binding, structural constituent of muscle Human UniProtKB:Q14315 MYOZ1 HPA UniProtKB {GO:0005515=PMID:10984498, GO:0030239=PMID:11114196, GO:0005634=GO_REF:0000052, GO:0051373=PMID:10984498, GO:0015629=GO_REF:0000019, GO:0031143=GO_REF:0000039} Q9NP98 Myozenin-1 protein 20110516 {GO:0005515=IPI, GO:0030239=TAS, GO:0005634=IDA, GO:0051373=IDA, GO:0015629=IEA, GO:0031143=IEA} myofibril assembly actin cytoskeleton, nucleus, pseudopodium FATZ binding, protein binding Human MYOZ2 BHF-UCL UniProtKB {GO:0005515=PMID:11114196, GO:0030346=PMID:11114196, GO:0008150=GO_REF:0000015, GO:0030018=PMID:15582318, GO:0031433=PMID:15582318, GO:0003779=GO_REF:0000019, GO:0015629=GO_REF:0000019, GO:0030017=PMID:11114196} Q9NPC6 Myozenin-2 protein 20120927 {GO:0005515=IPI, GO:0030346=NAS, GO:0008150=ND, GO:0030018=NAS, GO:0031433=IPI, GO:0003779=IEA, GO:0015629=IEA, GO:0030017=TAS} biological_process Z disc, actin cytoskeleton, sarcomere actin binding, protein binding, protein phosphatase 2B binding, telethonin binding Human MYOZ3 UniProtKB UniProtKB {GO:0005515=PMID:11842093, GO:0030018=GO_REF:0000039} Q8TDC0 Myozenin-3 protein 20060316 {GO:0005515=IPI, GO:0030018=IEA} Z disc protein binding Human UniProtKB:O15273 MYPN HPA UniProtKB {GO:0005515=PMID:11309420, GO:0008092=PMID:11309420, GO:0051371=PMID:11309420, GO:0030018=PMID:11309420, GO:0017124=PMID:11309420, GO:0015630=GO_REF:0000052, GO:0045214=PMID:11309420, GO:0005634=GO_REF:0000024, GO:0003779=GO_REF:0000037, GO:0031674=PMID:11309420} Q86TC9 Myopalladin protein 20110516 {GO:0005515=IPI, GO:0008092=IPI, GO:0051371=IPI, GO:0030018=IDA, GO:0017124=IPI, GO:0015630=IDA, GO:0045214=IMP, GO:0005634=ISS, GO:0003779=IEA, GO:0031674=IDA} sarcomere organization I band, Z disc, microtubule cytoskeleton, nucleus SH3 domain binding, actin binding, cytoskeletal protein binding, muscle alpha-actinin binding, protein binding Human MYPOP UniProtKB UniProtKB {GO:0003700=GO_REF:0000019, GO:0003682=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0000122=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q86VE0 Myb-related transcription factor, partner of profilin protein 20130413 {GO:0003700=IEA, GO:0003682=IEA, GO:0005634=IEA, GO:0000122=IEA, GO:0003677=IEA, GO:0042803=IEA, GO:0006351=IEA} negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding, chromatin binding, protein homodimerization activity, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0191 MYRIP UniProtKB UniProtKB {GO:0030133=GO_REF:0000039, GO:0005515=PMID:17827149, GO:0042470=GO_REF:0000019, GO:0048471=GO_REF:0000024, GO:0017137=GO_REF:0000002, GO:0031045=GO_REF:0000024, GO:0045202=GO_REF:0000019, GO:0003779=GO_REF:0000019, GO:0015629=GO_REF:0000019, GO:0006886=GO_REF:0000002, GO:0000145=GO_REF:0000019, GO:0008270=PMID:11964381, GO:0032024=GO_REF:0000024, GO:0051018=GO_REF:0000019, GO:0001750=GO_REF:0000019} Q8NFW9 Rab effector MyRIP protein 20120328 {GO:0030133=IEA, GO:0005515=IPI, GO:0042470=IEA, GO:0048471=ISS, GO:0017137=IEA, GO:0031045=ISS, GO:0045202=IEA, GO:0003779=IEA, GO:0015629=IEA, GO:0006886=IEA, GO:0000145=IEA, GO:0008270=NAS, GO:0032024=ISS, GO:0051018=IEA, GO:0001750=IEA} intracellular protein transport, positive regulation of insulin secretion actin cytoskeleton, dense core granule, exocyst, melanosome, perinuclear region of cytoplasm, photoreceptor outer segment, synapse, transport vesicle Rab GTPase binding, actin binding, protein binding, protein kinase A binding, zinc ion binding Human UniProtKB:P12367 MYSM1 UniProtKB UniProtKB {GO:0016578=PMID:18669648, GO:0004843=PMID:18669648, GO:0003713=PMID:18669648, GO:0005634=PMID:18669648, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0042393=PMID:18669648, GO:0003682=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0004221=PMID:18669648, GO:0045893=PMID:18669648, GO:0008237=PMID:18669648} Q5VVJ2 Histone H2A deubiquitinase MYSM1 protein 20090422 {GO:0016578=IDA, GO:0004843=IDA, GO:0003713=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA, GO:0046872=IEA, GO:0042393=IDA, GO:0003682=IEA, GO:0006508=IEA, GO:0004221=IDA, GO:0045893=IDA, GO:0008237=IMP} histone deubiquitination, positive regulation of transcription, DNA-dependent, proteolysis, transcription, DNA-dependent nucleus DNA binding, chromatin binding, histone binding, metal ion binding, metallopeptidase activity, transcription coactivator activity, ubiquitin thiolesterase activity, ubiquitin-specific protease activity Human MYT1 InterPro UniProtKB {GO:0006355=PMID:1280325, GO:0003700=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0007399=GO_REF:0000037} Q6P6D5 MYT1 protein protein 20130413 {GO:0006355=NAS, GO:0003700=IEA, GO:0008270=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0030154=IEA, GO:0006351=IEA, GO:0007399=IEA} cell differentiation, nervous system development, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human InterPro:IPR002515 MYT1L UniProtKB UniProtKB {GO:0003700=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000024, GO:0003677=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0007399=GO_REF:0000037} Q9UL68 Myelin transcription factor 1-like protein protein 20120103 {GO:0003700=IEA, GO:0008270=IEA, GO:0005634=ISS, GO:0003677=IEA, GO:0030154=IEA, GO:0006351=IEA, GO:0007399=IEA} cell differentiation, nervous system development, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB:P97500 MZB1 UniProtKB UniProtKB {GO:2001274=GO_REF:0000024, GO:0008284=GO_REF:0000019, GO:0034663=GO_REF:0000024, GO:0042127=GO_REF:0000024, GO:0005788=GO_REF:0000024, GO:0006915=GO_REF:0000037, GO:0030888=GO_REF:0000024, GO:0005576=GO_REF:0000039, GO:0033622=GO_REF:0000024, GO:0002642=GO_REF:0000024} Q8WU39 Marginal zone B- and B1-cell-specific protein protein 20121018 {GO:2001274=ISS, GO:0008284=IEA, GO:0034663=ISS, GO:0042127=ISS, GO:0005788=ISS, GO:0006915=IEA, GO:0030888=ISS, GO:0005576=IEA, GO:0033622=ISS, GO:0002642=ISS} apoptotic process, integrin activation, negative regulation of glucose import in response to insulin stimulus, positive regulation of cell proliferation, positive regulation of immunoglobulin biosynthetic process, regulation of B cell proliferation, regulation of cell proliferation endoplasmic reticulum chaperone complex, endoplasmic reticulum lumen, extracellular region Human UniProtKB:Q9D8I1 MZF1 HPA UniProtKB {GO:0005515=PMID:10777584, GO:0006355=PMID:15541732, GO:0003700=GO_REF:0000002, GO:0044212=PMID:15541732, GO:0016032=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0042803=PMID:16950398, GO:0006351=GO_REF:0000037} P28698 Myeloid zinc finger 1 protein 20090616 {GO:0005515=IPI, GO:0006355=IDA, GO:0003700=IEA, GO:0044212=IDA, GO:0016032=IEA, GO:0008270=IEA, GO:0005634=IDA, GO:0042803=IPI, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent, viral reproduction nucleus protein binding, protein homodimerization activity, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding, zinc ion binding Human MZT1 IntAct UniProtKB {GO:0005515=PMID:20360068, GO:0005813=PMID:20360068, GO:0005819=PMID:20360068, GO:0033566=PMID:20360068, GO:0008274=PMID:20360068} Q08AG7 Mitotic-spindle organizing protein 1 protein 20130415 {GO:0005515=IPI, GO:0005813=IDA, GO:0005819=IDA, GO:0033566=IMP, GO:0008274=IDA} gamma-tubulin complex localization centrosome, gamma-tubulin ring complex, spindle protein binding Human UniProtKB:P23258 MZT2A UniProtKB UniProtKB {GO:0005813=PMID:21399614, GO:0005819=GO_REF:0000024, GO:0008274=GO_REF:0000024} Q6P582 Mitotic-spindle organizing protein 2A protein 20110517 {GO:0005813=IDA, GO:0005819=ISS, GO:0008274=ISS} centrosome, gamma-tubulin ring complex, spindle Human MZT2B IntAct UniProtKB {GO:0005515=PMID:20360068, GO:0005813=PMID:21399614, GO:0005819=PMID:20360068, GO:0008274=PMID:20360068} Q6NZ67 Mitotic-spindle organizing protein 2B protein 20130415 {GO:0005515=IPI, GO:0005813=IDA, GO:0005819=IDA, GO:0008274=IDA} centrosome, gamma-tubulin ring complex, spindle protein binding Human UniProtKB:P23258 N4BP1 BHF-UCL UniProtKB {GO:0005515=PMID:21903422, GO:0034644=PMID:17592138, GO:0016605=GO_REF:0000024, GO:0005730=GO_REF:0000024, GO:0032435=GO_REF:0000024, GO:0031397=GO_REF:0000024} O75113 NEDD4-binding protein 1 protein 20130118 {GO:0005515=IPI, GO:0034644=IMP, GO:0016605=ISS, GO:0005730=ISS, GO:0032435=ISS, GO:0031397=ISS} cellular response to UV, negative regulation of proteasomal ubiquitin-dependent protein catabolic process, negative regulation of protein ubiquitination PML body, nucleolus protein binding Human N4BP2 MGI UniProtKB {GO:0005515=PMID:12730195, GO:0046404=PMID:12730195, GO:0004519=PMID:12730195, GO:0005524=PMID:12730195, GO:0005829=GO_REF:0000019} Q86UW6 NEDD4-binding protein 2 protein 20060110 {GO:0005515=IPI, GO:0046404=IDA, GO:0004519=IDA, GO:0005524=IDA, GO:0005829=IEA} cytosol ATP binding, ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity, endonuclease activity, protein binding Human N4BP2L2 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q92802 NEDD4-binding protein 2-like 2 protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human N4BP3 UniProtKB UniProtKB {GO:0030659=GO_REF:0000039} O15049 NEDD4-binding protein 3 protein 20130413 {GO:0030659=IEA} cytoplasmic vesicle membrane Human UniProtKB-SubCell:SL-0089 N6AMT1 GOC UniProtKB {GO:0005515=PMID:18539146, GO:0043234=PMID:18539146, GO:0030307=PMID:18539146, GO:0006479=PMID:18539146, GO:0008276=PMID:18539146, GO:0003676=GO_REF:0000002} Q9Y5N5 HemK methyltransferase family member 2 protein 20130413 {GO:0005515=IPI, GO:0043234=IDA, GO:0030307=IDA, GO:0006479=IDA, GO:0008276=IDA, GO:0003676=IEA} positive regulation of cell growth, protein methylation protein complex nucleic acid binding, protein binding, protein methyltransferase activity Human NAA10 IntAct UniProtKB {GO:0005622=GO_REF:0000054, GO:0005515=PMID:21295525, GO:0005737=PMID:15496142, GO:0008080=PMID:7981673, GO:0004596=GO_REF:0000003, GO:0043022=PMID:15496142, GO:0006323=PMID:7981673, GO:0005634=PMID:15496142, GO:0016407=PMID:15496142, GO:0006475=PMID:7981673, GO:0006474=PMID:15496142} P41227 N-alpha-acetyltransferase 10 protein 20130415 {GO:0005622=IDA, GO:0005515=IPI, GO:0005737=IDA, GO:0008080=TAS, GO:0004596=IEA, GO:0043022=IDA, GO:0006323=TAS, GO:0005634=IDA, GO:0016407=IDA, GO:0006475=TAS, GO:0006474=IDA} DNA packaging, N-terminal protein amino acid acetylation, internal protein amino acid acetylation cytoplasm, intracellular, nucleus N-acetyltransferase activity, acetyltransferase activity, peptide alpha-N-acetyltransferase activity, protein binding, ribosome binding Human UniProtKB:Q15052 NAA11 HPA UniProtKB {GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0004596=GO_REF:0000003, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9BSU3 N-alpha-acetyltransferase 11 protein 20110516 {GO:0005813=IDA, GO:0005737=IDA, GO:0005794=IDA, GO:0004596=IEA, GO:0005730=IDA, GO:0005634=IDA} Golgi apparatus, centrosome, cytoplasm, nucleolus, nucleus peptide alpha-N-acetyltransferase activity Human NAA15 HPA UniProtKB {GO:0005515=PMID:16507339, GO:0005667=PMID:12145306, GO:0005737=GO_REF:0000052, GO:0008080=GO_REF:0000019, GO:0043022=PMID:15496142, GO:0016407=PMID:15496142, GO:0005634=PMID:12145306, GO:0001525=GO_REF:0000037, GO:0045893=PMID:12145306, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0006474=PMID:15496142} Q9BXJ9 N-alpha-acetyltransferase 15, NatA auxiliary subunit protein 20101115 {GO:0005515=IPI, GO:0005667=IDA, GO:0005737=IDA, GO:0008080=IEA, GO:0043022=IDA, GO:0016407=IDA, GO:0005634=IDA, GO:0001525=IEA, GO:0045893=IDA, GO:0030154=IEA, GO:0006351=IEA, GO:0006474=IDA} N-terminal protein amino acid acetylation, angiogenesis, cell differentiation, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus, transcription factor complex N-acetyltransferase activity, acetyltransferase activity, protein binding, ribosome binding Human NAA16 HPA UniProtKB {GO:0005667=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0043022=GO_REF:0000024, GO:0016407=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0045893=GO_REF:0000024, GO:0006474=GO_REF:0000024} Q6N069 N-alpha-acetyltransferase 16, NatA auxiliary subunit protein 20111111 {GO:0005667=ISS, GO:0005737=IDA, GO:0043022=ISS, GO:0016407=ISS, GO:0005634=ISS, GO:0045893=ISS, GO:0006474=ISS} N-terminal protein amino acid acetylation, positive regulation of transcription, DNA-dependent cytoplasm, nucleus, transcription factor complex acetyltransferase activity, ribosome binding Human NAA20 LIFEdb UniProtKB {GO:0005622=GO_REF:0000054, GO:0005737=GO_REF:0000039, GO:0008080=GO_REF:0000002, GO:0004596=GO_REF:0000003, GO:0005634=GO_REF:0000039} P61599 N-alpha-acetyltransferase 20 protein 20100607 {GO:0005622=IDA, GO:0005737=IEA, GO:0008080=IEA, GO:0004596=IEA, GO:0005634=IEA} cytoplasm, intracellular, nucleus N-acetyltransferase activity, peptide alpha-N-acetyltransferase activity Human NAA25 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q14CX7 N-alpha-acetyltransferase 25, NatB auxiliary subunit protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 NAA30 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0008080=GO_REF:0000002, GO:0004596=GO_REF:0000003} Q147X3 N-alpha-acetyltransferase 30 protein 20130413 {GO:0005737=IEA, GO:0008080=IEA, GO:0004596=IEA} cytoplasm N-acetyltransferase activity, peptide alpha-N-acetyltransferase activity Human UniProtKB-SubCell:SL-0086 NAA35 UniProtKB UniProtKB {GO:0005737=GO_REF:0000052, GO:0048659=GO_REF:0000024, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0016740=GO_REF:0000038} Q5VZE6 N-alpha-acetyltransferase 35, NatC auxiliary subunit protein 20130413 {GO:0005737=IDA, GO:0048659=ISS, GO:0005886=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0016740=IEA} smooth muscle cell proliferation cytoplasm, nucleolus, nucleus, plasma membrane transferase activity Human UniProtKB-KW:KW-0808 NAA38 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0000398=GO_REF:0000029, GO:0005634=GO_REF:0000029, GO:0005681=GO_REF:0000037, GO:0017070=PMID:10523320} O95777 N-alpha-acetyltransferase 38, NatC auxiliary subunit protein 20130415 {GO:0005515=IPI, GO:0000398=NAS, GO:0005634=NAS, GO:0005681=IEA, GO:0017070=NAS} mRNA splicing, via spliceosome nucleus, spliceosomal complex U6 snRNA binding, protein binding Human UniProtKB:P62310 NAA40 InterPro UniProtKB {GO:0008080=GO_REF:0000002} Q86UY6 N-alpha-acetyltransferase 40 protein 20130413 {GO:0008080=IEA} N-acetyltransferase activity Human InterPro:IPR000182 NAA50 HGNC UniProtKB {GO:0005515=PMID:16507339, GO:0005737=PMID:16507339, GO:0008080=GO_REF:0000002, GO:0006474=PMID:16507339} Q9GZZ1 N-alpha-acetyltransferase 50 protein 20060518 {GO:0005515=IPI, GO:0005737=IDA, GO:0008080=IEA, GO:0006474=TAS} N-terminal protein amino acid acetylation cytoplasm N-acetyltransferase activity, protein binding Human NAAA MGI UniProtKB {GO:0006629=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005737=PMID:10610717, GO:0016810=PMID:17980170, GO:0016787=GO_REF:0000002, GO:0005764=GO_REF:0000039, GO:0008134=PMID:21106534} Q02083 N-acylethanolamine-hydrolyzing acid amidase protein 20120229 {GO:0006629=IEA, GO:0003674=ND, GO:0008150=ND, GO:0005737=IDA, GO:0016810=IDA, GO:0016787=IEA, GO:0005764=IEA, GO:0008134=IPI} biological_process, lipid metabolic process cytoplasm, lysosome hydrolase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, molecular_function, transcription factor binding Human NAALADL2 UniProtKB UniProtKB {GO:0006508=GO_REF:0000002, GO:0008233=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q58DX5 Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2 protein 20130413 {GO:0006508=IEA, GO:0008233=IEA, GO:0016021=IEA} proteolysis integral to membrane peptidase activity Human UniProtKB-KW:KW-0812 NAB1 UniProtKB UniProtKB {GO:0014037=GO_REF:0000019, GO:0006355=PMID:8668170, GO:0001958=GO_REF:0000019, GO:0042552=GO_REF:0000019, GO:0045682=GO_REF:0000019, GO:0005634=PMID:8668170, GO:0045892=PMID:8668170, GO:0006351=GO_REF:0000037, GO:0008134=GO_REF:0000019} Q13506 NGFI-A-binding protein 1 protein 20010918 {GO:0014037=IEA, GO:0006355=NAS, GO:0001958=IEA, GO:0042552=IEA, GO:0045682=IEA, GO:0005634=NAS, GO:0045892=NAS, GO:0006351=IEA, GO:0008134=IEA} Schwann cell differentiation, endochondral ossification, myelination, negative regulation of transcription, DNA-dependent, regulation of epidermis development, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus transcription factor binding Human NAB2 PINC UniProtKB {GO:0014037=GO_REF:0000019, GO:0001958=GO_REF:0000019, GO:0008283=PMID:8668170, GO:0003714=PMID:8668170, GO:0042552=GO_REF:0000019, GO:0045682=GO_REF:0000019, GO:0016480=PMID:8668170, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037, GO:0007399=PMID:8668170, GO:0008134=GO_REF:0000019} Q15742 NGFI-A-binding protein 2 protein 20030904 {GO:0014037=IEA, GO:0001958=IEA, GO:0008283=TAS, GO:0003714=TAS, GO:0042552=IEA, GO:0045682=IEA, GO:0016480=IDA, GO:0005634=IEA, GO:0006351=IEA, GO:0007399=TAS, GO:0008134=IEA} Schwann cell differentiation, cell proliferation, endochondral ossification, myelination, negative regulation of transcription from RNA polymerase III promoter, nervous system development, regulation of epidermis development, transcription, DNA-dependent nucleus transcription corepressor activity, transcription factor binding Human NACA BHF-UCL UniProtKB {GO:1901228=GO_REF:0000024, GO:0005515=PMID:21903422, GO:1901227=GO_REF:0000024, GO:0003713=GO_REF:0000024, GO:0048742=GO_REF:0000024, GO:0061384=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0015031=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0006412=PMID:8047162, GO:2000138=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0005737=GO_REF:0000024, GO:0048633=GO_REF:0000024, GO:0019048=GO_REF:0000037, GO:0017025=GO_REF:0000024, GO:0043403=GO_REF:0000024, GO:0005854=PMID:8047162, GO:0003231=GO_REF:0000024} Q13765 Nascent polypeptide-associated complex subunit alpha protein 20121128 {GO:1901228=ISS, GO:0005515=IPI, GO:1901227=ISS, GO:0003713=ISS, GO:0048742=ISS, GO:0061384=ISS, GO:0005634=ISS, GO:0015031=IEA, GO:0003677=IEA, GO:0006412=TAS, GO:2000138=ISS, GO:0006351=IEA, GO:0005737=ISS, GO:0048633=ISS, GO:0019048=IEA, GO:0017025=ISS, GO:0043403=ISS, GO:0005854=TAS, GO:0003231=ISS} cardiac ventricle development, heart trabecula morphogenesis, negative regulation of transcription from RNA polymerase II promoter involved in heart development, positive regulation of cell proliferation involved in heart morphogenesis, positive regulation of skeletal muscle tissue growth, positive regulation of transcription from RNA polymerase II promoter involved in heart development, protein transport, regulation of skeletal muscle fiber development, skeletal muscle tissue regeneration, transcription, DNA-dependent, translation, virus-host interaction cytoplasm, nascent polypeptide-associated complex, nucleus DNA binding, TBP-class protein binding, protein binding, transcription coactivator activity Human UniProtKB:Q60817 NACA2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0003713=GO_REF:0000019, GO:0017025=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0015031=GO_REF:0000037} Q9H009 Nascent polypeptide-associated complex subunit alpha-2 protein 20130413 {GO:0005737=IEA, GO:0003713=IEA, GO:0017025=IEA, GO:0005634=IEA, GO:0015031=IEA} protein transport cytoplasm, nucleus TBP-class protein binding, transcription coactivator activity Human UniProtKB-SubCell:SL-0086 NACAD UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0015031=GO_REF:0000037} O15069 NAC-alpha domain-containing protein 1 protein 20130413 {GO:0005737=IEA, GO:0005634=IEA, GO:0015031=IEA} protein transport cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 NACC1 HPA UniProtKB {GO:0016604=PMID:17130457, GO:0008284=PMID:17804717, GO:0005737=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0051260=PMID:17130457, GO:0006917=GO_REF:0000019, GO:0045892=PMID:17804717, GO:0006351=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q96RE7 Nucleus accumbens-associated protein 1 protein 20090616 {GO:0016604=IDA, GO:0008284=IMP, GO:0005737=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0051260=IDA, GO:0006917=IEA, GO:0045892=IMP, GO:0006351=IEA, GO:0043231=IDA} induction of apoptosis, negative regulation of transcription, DNA-dependent, positive regulation of cell proliferation, protein homooligomerization, transcription, DNA-dependent cytoplasm, intracellular membrane-bounded organelle, nuclear body, nucleolus, nucleus Human NACC2 GOC UniProtKB {GO:0005515=PMID:22926524, GO:0016575=PMID:22926524, GO:0008284=GO_REF:0000024, GO:0000790=PMID:22926524, GO:0008285=PMID:22926524, GO:0006366=PMID:22926524, GO:0008630=PMID:22926524, GO:0042826=PMID:22926524, GO:0005634=GO_REF:0000024, GO:0000978=PMID:22926524, GO:0042803=PMID:22926524, GO:0001078=PMID:22926524, GO:0016604=GO_REF:0000024, GO:0010608=PMID:22926524, GO:0001076=PMID:22926524, GO:0016581=PMID:22926524, GO:0034629=PMID:22926524, GO:1900477=PMID:22926524, GO:0051260=GO_REF:0000024, GO:0004407=PMID:22926524, GO:0045892=GO_REF:0000024} Q96BF6 Nucleus accumbens-associated protein 2 protein 20130413 {GO:0005515=IPI, GO:0016575=IDA, GO:0008284=ISS, GO:0000790=IDA, GO:0008285=IDA, GO:0006366=IDA, GO:0008630=IDA, GO:0042826=IPI, GO:0005634=ISS, GO:0000978=IDA, GO:0042803=IDA, GO:0001078=IDA, GO:0016604=ISS, GO:0010608=IMP, GO:0001076=IDA, GO:0016581=IDA, GO:0034629=IDA, GO:1900477=IDA, GO:0051260=ISS, GO:0004407=IDA, GO:0045892=ISS} cellular protein complex localization, histone deacetylation, intrinsic apoptotic signaling pathway in response to DNA damage, negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter, negative regulation of cell proliferation, negative regulation of transcription, DNA-dependent, positive regulation of cell proliferation, posttranscriptional regulation of gene expression, protein homooligomerization, transcription from RNA polymerase II promoter NuRD complex, nuclear body, nuclear chromatin, nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, RNA polymerase II transcription factor binding transcription factor activity, histone deacetylase activity, histone deacetylase binding, protein binding, protein homodimerization activity Human NADK InterPro UniProtKB {GO:0016310=PMID:11594753, GO:0006741=GO_REF:0000002, GO:0046034=PMID:11594753, GO:0003951=GO_REF:0000002, GO:0006766=Reactome:REACT_11193, GO:0019674=GO_REF:0000002, GO:0006767=Reactome:REACT_11238, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_11234} Q5QPS5 NAD kinase protein 20130413 {GO:0016310=NAS, GO:0006741=IEA, GO:0046034=NAS, GO:0003951=IEA, GO:0006766=TAS, GO:0019674=IEA, GO:0006767=TAS, GO:0044281=TAS, GO:0005524=IEA, GO:0046872=IEA, GO:0005829=TAS} ATP metabolic process, NAD metabolic process, NADP biosynthetic process, phosphorylation, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cytosol ATP binding, NAD+ kinase activity, metal ion binding Human InterPro:IPR002504 NADKD1 UniProtKB UniProtKB {GO:0005739=PMID:23212377, GO:0006741=GO_REF:0000002, GO:0003951=PMID:23212377, GO:0019674=PMID:23212377, GO:0005524=GO_REF:0000037, GO:0042803=PMID:23212377} Q4G0N4 NAD kinase domain-containing protein 1, mitochondrial protein 20130118 {GO:0005739=IDA, GO:0006741=IEA, GO:0003951=IDA, GO:0019674=IDA, GO:0005524=IEA, GO:0042803=IDA} NAD metabolic process, NADP biosynthetic process mitochondrion ATP binding, NAD+ kinase activity, protein homodimerization activity Human NADSYN1 Reactome UniProtKB {GO:0006807=GO_REF:0000002, GO:0003952=Reactome:REACT_11135, GO:0016810=GO_REF:0000002, GO:0006766=Reactome:REACT_11193, GO:0019674=Reactome:REACT_11088, GO:0006767=Reactome:REACT_11238, GO:0044281=Reactome:REACT_111217, GO:0009435=GO_REF:0000041, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_11135} Q6IA69 Glutamine-dependent NAD(+) synthetase protein 20070502 {GO:0006807=IEA, GO:0003952=TAS, GO:0016810=IEA, GO:0006766=TAS, GO:0019674=TAS, GO:0006767=TAS, GO:0044281=TAS, GO:0009435=IEA, GO:0005524=IEA, GO:0005829=TAS} NAD biosynthetic process, NAD metabolic process, nitrogen compound metabolic process, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cytosol ATP binding, NAD+ synthase (glutamine-hydrolyzing) activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds Human NAE1 PINC UniProtKB {GO:0005515=PMID:15361859, GO:0005886=GO_REF:0000039, GO:0046982=PMID:12740388, GO:0045116=PMID:12740388, GO:0006915=GO_REF:0000037, GO:0042981=PMID:14557245, GO:0003824=GO_REF:0000002, GO:0006260=PMID:14557245, GO:0007165=PMID:8626687, GO:0005737=PMID:8626687, GO:0033314=PMID:10722740, GO:0019781=PMID:12740388, GO:0031625=PMID:18627766} Q13564 NEDD8-activating enzyme E1 regulatory subunit protein 20030904 {GO:0005515=IPI, GO:0005886=IEA, GO:0046982=IPI, GO:0045116=IDA, GO:0006915=IEA, GO:0042981=IDA, GO:0003824=IEA, GO:0006260=IDA, GO:0007165=TAS, GO:0005737=TAS, GO:0033314=IDA, GO:0019781=IDA, GO:0031625=IPI} DNA replication, apoptotic process, mitotic DNA replication checkpoint, protein neddylation, regulation of apoptotic process, signal transduction cytoplasm, plasma membrane NEDD8 activating enzyme activity, catalytic activity, protein binding, protein heterodimerization activity, ubiquitin protein ligase binding Human NAF1 HPA UniProtKB {GO:0005515=PMID:16601202, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0030054=GO_REF:0000052, GO:0030515=GO_REF:0000002, GO:0042254=PMID:16618814, GO:0003723=PMID:16618814, GO:0006364=GO_REF:0000037, GO:0005732=PMID:17135485, GO:0005634=GO_REF:0000039, GO:0031120=GO_REF:0000002} Q96HR8 H/ACA ribonucleoprotein complex non-core subunit NAF1 protein 20110516 {GO:0005515=IPI, GO:0005813=IDA, GO:0005737=IDA, GO:0030054=IDA, GO:0030515=IEA, GO:0042254=IDA, GO:0003723=IDA, GO:0006364=IEA, GO:0005732=IDA, GO:0005634=IEA, GO:0031120=IEA} rRNA processing, ribosome biogenesis, snRNA pseudouridine synthesis cell junction, centrosome, cytoplasm, nucleus, small nucleolar ribonucleoprotein complex RNA binding, protein binding, snoRNA binding Human NAGA UniProtKB UniProtKB {GO:0005737=GO_REF:0000033, GO:0016052=PMID:19683538, GO:0009311=GO_REF:0000033, GO:0046477=GO_REF:0000033, GO:0019377=PMID:9741689, GO:0016139=GO_REF:0000033, GO:0004557=GO_REF:0000033, GO:0008456=PMID:19683538, GO:0005764=GO_REF:0000039, GO:0042803=PMID:19683538} P17050 Alpha-N-acetylgalactosaminidase protein 20091105 {GO:0005737=IBA, GO:0016052=IDA, GO:0009311=IBA, GO:0046477=IBA, GO:0019377=IMP, GO:0016139=IBA, GO:0004557=IBA, GO:0008456=IDA, GO:0005764=IEA, GO:0042803=IPI} carbohydrate catabolic process, glycolipid catabolic process, glycoside catabolic process, glycosylceramide catabolic process, oligosaccharide metabolic process cytoplasm, lysosome alpha-N-acetylgalactosaminidase activity, alpha-galactosidase activity, protein homodimerization activity Human NAGK IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0006051=PMID:10824116, GO:0006044=PMID:10824116, GO:0045127=PMID:22692205, GO:0009384=GO_REF:0000019, GO:0019262=PMID:22692205, GO:0005524=GO_REF:0000037} Q9UJ70 N-acetyl-D-glucosamine kinase protein 20130415 {GO:0005515=IPI, GO:0006051=TAS, GO:0006044=TAS, GO:0045127=IDA, GO:0009384=IEA, GO:0019262=TAS, GO:0005524=IEA} N-acetylglucosamine metabolic process, N-acetylmannosamine metabolic process, N-acetylneuraminate catabolic process ATP binding, N-acetylglucosamine kinase activity, N-acylmannosamine kinase activity, protein binding Human UniProtKB:Q8TBB1 NAGLU Reactome UniProtKB {GO:0045475=GO_REF:0000019, GO:0005975=Reactome:REACT_474, GO:0004561=GO_REF:0000003, GO:0046548=GO_REF:0000019, GO:0060119=GO_REF:0000019, GO:0006027=Reactome:REACT_120752, GO:0044281=Reactome:REACT_111217, GO:0005764=PMID:8650226, GO:0007399=PMID:8650226, GO:0021680=GO_REF:0000019, GO:0042474=GO_REF:0000019, GO:0007040=GO_REF:0000019, GO:0030203=Reactome:REACT_121315, GO:0043202=Reactome:REACT_121018} P54802 Alpha-N-acetylglucosaminidase protein 20130301 {GO:0045475=IEA, GO:0005975=TAS, GO:0004561=IEA, GO:0046548=IEA, GO:0060119=IEA, GO:0006027=TAS, GO:0044281=TAS, GO:0005764=TAS, GO:0007399=TAS, GO:0021680=IEA, GO:0042474=IEA, GO:0007040=IEA, GO:0030203=TAS, GO:0043202=TAS} carbohydrate metabolic process, cerebellar Purkinje cell layer development, glycosaminoglycan catabolic process, glycosaminoglycan metabolic process, inner ear receptor cell development, locomotor rhythm, lysosome organization, middle ear morphogenesis, nervous system development, retinal rod cell development, small molecule metabolic process lysosomal lumen, lysosome alpha-N-acetylglucosaminidase activity Human NAGPA PINC UniProtKB {GO:0005975=PMID:10551838, GO:0003944=GO_REF:0000003, GO:0032580=GO_REF:0000039, GO:0006622=PMID:10551838, GO:0006486=GO_REF:0000041, GO:0016021=GO_REF:0000037, GO:0007040=PMID:10551838, GO:0006464=PMID:10551838} Q9UK23 N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase protein 20030904 {GO:0005975=TAS, GO:0003944=IEA, GO:0032580=IEA, GO:0006622=TAS, GO:0006486=IEA, GO:0016021=IEA, GO:0007040=TAS, GO:0006464=TAS} carbohydrate metabolic process, cellular protein modification process, lysosome organization, protein glycosylation, protein targeting to lysosome Golgi cisterna membrane, integral to membrane N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity Human NAGS BHF-UCL UniProtKB {GO:0034641=Reactome:REACT_13, GO:0006536=PMID:21757002, GO:0005759=Reactome:REACT_2139, GO:0000050=Reactome:REACT_847, GO:0006526=GO_REF:0000041, GO:0008652=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0016740=GO_REF:0000038, GO:0004042=PMID:21757002} Q8N159 N-acetylglutamate synthase, mitochondrial protein 20111201 {GO:0034641=TAS, GO:0006536=TAS, GO:0005759=TAS, GO:0000050=TAS, GO:0006526=IEA, GO:0008652=IEA, GO:0044281=TAS, GO:0016740=IEA, GO:0004042=TAS} arginine biosynthetic process, cellular amino acid biosynthetic process, cellular nitrogen compound metabolic process, glutamate metabolic process, small molecule metabolic process, urea cycle mitochondrial matrix acetyl-CoA:L-glutamate N-acetyltransferase activity, transferase activity Human NAIF1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0006915=GO_REF:0000037, GO:0005634=PMID:16378748, GO:0006917=PMID:16378748} Q69YI7 Nuclear apoptosis-inducing factor 1 protein 20080519 {GO:0003674=ND, GO:0006915=IEA, GO:0005634=IDA, GO:0006917=IDA} apoptotic process, induction of apoptosis nucleus molecular_function Human NAIP PINC UniProtKB {GO:0005515=PMID:21371431, GO:0017111=GO_REF:0000002, GO:0043066=GO_REF:0000024, GO:0004869=GO_REF:0000037, GO:0005524=PMID:21371431, GO:0046872=GO_REF:0000037, GO:0007399=PMID:7813013, GO:0016323=GO_REF:0000024, GO:0043524=PMID:18414036, GO:0005737=GO_REF:0000024, GO:0006954=GO_REF:0000037, GO:0045087=GO_REF:0000037, GO:0043154=PMID:11896143} Q13075 Baculoviral IAP repeat-containing protein 1 protein 20030904 {GO:0005515=IPI, GO:0017111=IEA, GO:0043066=ISS, GO:0004869=IEA, GO:0005524=IMP, GO:0046872=IEA, GO:0007399=TAS, GO:0016323=ISS, GO:0043524=TAS, GO:0005737=ISS, GO:0006954=IEA, GO:0045087=IEA, GO:0043154=IDA} inflammatory response, innate immune response, negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of neuron apoptotic process, nervous system development basolateral plasma membrane, cytoplasm ATP binding, cysteine-type endopeptidase inhibitor activity, metal ion binding, nucleoside-triphosphatase activity, protein binding Human NALCN GOC UniProtKB {GO:0034220=Reactome:REACT_25300, GO:0005244=GO_REF:0000037, GO:0005886=Reactome:REACT_160155, GO:0005272=Reactome:REACT_160155, GO:0035725=Reactome:REACT_160155, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0005216=GO_REF:0000002} Q8IZF0 Sodium leak channel non-selective protein protein 20130413 {GO:0034220=TAS, GO:0005244=IEA, GO:0005886=TAS, GO:0005272=TAS, GO:0035725=TAS, GO:0016021=IEA, GO:0055085=TAS, GO:0005216=IEA} ion transmembrane transport, sodium ion transmembrane transport, transmembrane transport integral to membrane, plasma membrane ion channel activity, sodium channel activity, voltage-gated ion channel activity Human NAMPT BHF-UCL UniProtKB {GO:0008286=PMID:17983582, GO:0047280=GO_REF:0000003, GO:0008284=PMID:8289818, GO:0007267=PMID:8289818, GO:0019674=Reactome:REACT_11088, GO:0006767=Reactome:REACT_11238, GO:0044281=Reactome:REACT_111217, GO:0006769=Reactome:REACT_11213, GO:0005125=PMID:8289818, GO:0005829=Reactome:REACT_115946, GO:0004516=GO_REF:0000002, GO:0007165=PMID:8289818, GO:0006766=Reactome:REACT_11193, GO:0045944=PMID:23001182, GO:0004514=GO_REF:0000002, GO:0009435=GO_REF:0000041, GO:0051770=PMID:19727662, GO:0060612=PMID:17983582} P43490 Nicotinamide phosphoribosyltransferase protein 20121121 {GO:0008286=IDA, GO:0047280=IEA, GO:0008284=TAS, GO:0007267=TAS, GO:0019674=TAS, GO:0006767=TAS, GO:0044281=TAS, GO:0006769=TAS, GO:0005125=TAS, GO:0005829=TAS, GO:0004516=IEA, GO:0007165=TAS, GO:0006766=TAS, GO:0045944=IDA, GO:0004514=IEA, GO:0009435=IEA, GO:0051770=IDA, GO:0060612=IDA} NAD biosynthetic process, NAD metabolic process, adipose tissue development, cell-cell signaling, insulin receptor signaling pathway, nicotinamide metabolic process, positive regulation of cell proliferation, positive regulation of nitric-oxide synthase biosynthetic process, positive regulation of transcription from RNA polymerase II promoter, signal transduction, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cytosol cytokine activity, nicotinamide phosphoribosyltransferase activity, nicotinate phosphoribosyltransferase activity, nicotinate-nucleotide diphosphorylase (carboxylating) activity Human NANOG BHF-UCL UniProtKB {GO:0010468=PMID:18388306, GO:0006355=PMID:16153702, GO:0003700=PMID:16153702, GO:0008283=PMID:16501172, GO:0003714=GO_REF:0000024, GO:0005730=PMID:20458727, GO:0005634=PMID:18932205, GO:0009790=PMID:15108323, GO:0003677=PMID:16153702, GO:0001714=PMID:20713518, GO:0030154=PMID:16501172, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0045944=PMID:20713518, GO:0045595=PMID:16501172, GO:0035019=PMID:18388306} Q9H9S0 Homeobox protein NANOG protein 20121024 {GO:0010468=IMP, GO:0006355=IDA, GO:0003700=IDA, GO:0008283=IMP, GO:0003714=ISS, GO:0005730=IDA, GO:0005634=IDA, GO:0009790=IEP, GO:0003677=IDA, GO:0001714=IDA, GO:0030154=IEP, GO:0006351=IEA, GO:0043565=IEA, GO:0045944=IDA, GO:0045595=IMP, GO:0035019=IMP} cell differentiation, cell proliferation, embryo development, endodermal cell fate specification, positive regulation of transcription from RNA polymerase II promoter, regulation of cell differentiation, regulation of gene expression, regulation of transcription, DNA-dependent, somatic stem cell maintenance, transcription, DNA-dependent nucleolus, nucleus DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human NANOS1 GOC UniProtKB {GO:0017148=GO_REF:0000024, GO:0005515=PMID:17047063, GO:0005737=PMID:12690449, GO:0048471=PMID:17047063, GO:0016477=PMID:18223680, GO:0003723=GO_REF:0000037, GO:0010631=PMID:17047063, GO:0008270=GO_REF:0000002, GO:0030371=GO_REF:0000024} Q8WY41 Nanos homolog 1 protein 20130413 {GO:0017148=ISS, GO:0005515=IPI, GO:0005737=IDA, GO:0048471=IDA, GO:0016477=IDA, GO:0003723=IEA, GO:0010631=IDA, GO:0008270=IEA, GO:0030371=ISS} cell migration, epithelial cell migration, negative regulation of translation cytoplasm, perinuclear region of cytoplasm RNA binding, protein binding, translation repressor activity, zinc ion binding Human UniProtKB:Q07937 NANOS3 UniProtKB UniProtKB {GO:0043066=GO_REF:0000024, GO:0048477=GO_REF:0000019, GO:0010494=GO_REF:0000024, GO:0003723=GO_REF:0000024, GO:0007275=GO_REF:0000037, GO:0005634=PMID:21421998, GO:0007283=GO_REF:0000024, GO:0007281=PMID:21421998, GO:0006417=GO_REF:0000024, GO:0005737=PMID:21421998, GO:0000932=GO_REF:0000024, GO:0051726=GO_REF:0000024, GO:0008270=GO_REF:0000002} P60323 Nanos homolog 3 protein 20110413 {GO:0043066=ISS, GO:0048477=IEA, GO:0010494=ISS, GO:0003723=ISS, GO:0007275=IEA, GO:0005634=IDA, GO:0007283=ISS, GO:0007281=IMP, GO:0006417=ISS, GO:0005737=IDA, GO:0000932=ISS, GO:0051726=ISS, GO:0008270=IEA} germ cell development, multicellular organismal development, negative regulation of apoptotic process, oogenesis, regulation of cell cycle, regulation of translation, spermatogenesis cytoplasm, cytoplasmic mRNA processing body, cytoplasmic stress granule, nucleus RNA binding, zinc ion binding Human UniProtKB:P60324 NANS UniProtKB UniProtKB {GO:0016051=GO_REF:0000002, GO:0005737=PMID:10749855, GO:0050462=GO_REF:0000003, GO:0008781=PMID:10749855, GO:0003824=GO_REF:0000002, GO:0009103=PMID:10749855, GO:0005829=GO_REF:0000019, GO:0047444=GO_REF:0000003} Q9NR45 Sialic acid synthase protein 20010921 {GO:0016051=IEA, GO:0005737=NAS, GO:0050462=IEA, GO:0008781=NAS, GO:0003824=IEA, GO:0009103=NAS, GO:0005829=IEA, GO:0047444=IEA} carbohydrate biosynthetic process, lipopolysaccharide biosynthetic process cytoplasm, cytosol N-acetylneuraminate synthase activity, N-acylneuraminate cytidylyltransferase activity, N-acylneuraminate-9-phosphate synthase activity, catalytic activity Human NAP1L1 IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0006260=PMID:8297347, GO:0042470=GO_REF:0000039, GO:0008284=PMID:8297347, GO:0006334=GO_REF:0000002, GO:0005634=GO_REF:0000039} P55209 Nucleosome assembly protein 1-like 1 protein 20130415 {GO:0005515=IPI, GO:0006260=TAS, GO:0042470=IEA, GO:0008284=TAS, GO:0006334=IEA, GO:0005634=IEA} DNA replication, nucleosome assembly, positive regulation of cell proliferation melanosome, nucleus protein binding Human UniProtKB:P10588 NAP1L2 UniProtKB UniProtKB {GO:0006334=GO_REF:0000002, GO:0005634=GO_REF:0000039} Q9ULW6 Nucleosome assembly protein 1-like 2 protein 20130413 {GO:0006334=IEA, GO:0005634=IEA} nucleosome assembly nucleus Human UniProtKB-SubCell:SL-0191 NAP1L4 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0005737=PMID:9325046, GO:0006334=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0051082=PMID:9325046} Q99733 Nucleosome assembly protein 1-like 4 protein 20130415 {GO:0005515=IPI, GO:0005737=TAS, GO:0006334=IEA, GO:0005634=IEA, GO:0051082=TAS} nucleosome assembly cytoplasm, nucleus protein binding, unfolded protein binding Human UniProtKB:P04608 NAP1L5 UniProtKB UniProtKB {GO:0006334=GO_REF:0000002, GO:0005634=GO_REF:0000039} Q96NT1 Nucleosome assembly protein 1-like 5 protein 20130413 {GO:0006334=IEA, GO:0005634=IEA} nucleosome assembly nucleus Human UniProtKB-SubCell:SL-0191 NAPA IntAct UniProtKB {GO:0019905=GO_REF:0000019, GO:0035494=GO_REF:0000019, GO:0005515=PMID:16189514, GO:0006892=Reactome:REACT_11235, GO:0010807=GO_REF:0000019, GO:0035249=GO_REF:0000019, GO:0006891=PMID:8455721, GO:0045176=GO_REF:0000019, GO:0006886=GO_REF:0000019, GO:0005829=Reactome:REACT_19390, GO:0006944=PMID:8455721, GO:0007420=GO_REF:0000019, GO:0030182=GO_REF:0000019, GO:0016044=Reactome:REACT_11123, GO:0070044=GO_REF:0000019} P54920 Alpha-soluble NSF attachment protein protein 20130415 {GO:0019905=IEA, GO:0035494=IEA, GO:0005515=IPI, GO:0006892=TAS, GO:0010807=IEA, GO:0035249=IEA, GO:0006891=TAS, GO:0045176=IEA, GO:0006886=IEA, GO:0005829=TAS, GO:0006944=TAS, GO:0007420=IEA, GO:0030182=IEA, GO:0016044=TAS, GO:0070044=IEA} SNARE complex disassembly, apical protein localization, brain development, cellular membrane fusion, cellular membrane organization, intra-Golgi vesicle-mediated transport, intracellular protein transport, neuron differentiation, post-Golgi vesicle-mediated transport, regulation of synaptic vesicle priming, synaptic transmission, glutamatergic cytosol, synaptobrevin 2-SNAP-25-syntaxin-1a complex protein binding, syntaxin binding Human UniProtKB:Q12846 NAPB ENSEMBL UniProtKB {GO:0035494=GO_REF:0000019, GO:0019905=GO_REF:0000019, GO:0035249=GO_REF:0000019, GO:0010807=GO_REF:0000019, GO:0006886=GO_REF:0000002, GO:0070044=GO_REF:0000019} Q9H115 Beta-soluble NSF attachment protein protein 20130413 {GO:0035494=IEA, GO:0019905=IEA, GO:0035249=IEA, GO:0010807=IEA, GO:0006886=IEA, GO:0070044=IEA} SNARE complex disassembly, intracellular protein transport, regulation of synaptic vesicle priming, synaptic transmission, glutamatergic synaptobrevin 2-SNAP-25-syntaxin-1a complex syntaxin binding Human Ensembl:ENSMUSP00000028926 NAPEPLD Reactome UniProtKB {GO:0016787=GO_REF:0000002, GO:0042622=Reactome:REACT_160080, GO:0070290=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0004620=GO_REF:0000019, GO:0009395=GO_REF:0000037} Q6IQ20 N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D protein 20121116 {GO:0016787=IEA, GO:0042622=TAS, GO:0070290=IEA, GO:0008270=IEA, GO:0004620=IEA, GO:0009395=IEA} phospholipid catabolic process photoreceptor outer segment membrane NAPE-specific phospholipase D activity, hydrolase activity, phospholipase activity, zinc ion binding Human NAPG PINC UniProtKB {GO:0005739=PMID:11278501, GO:0005515=PMID:11278501, GO:0006461=PMID:11278501, GO:0006944=PMID:8455721, GO:0016020=GO_REF:0000039, GO:0050821=PMID:11278501, GO:0006891=PMID:8455721, GO:0006886=GO_REF:0000002} Q99747 Gamma-soluble NSF attachment protein protein 20030904 {GO:0005739=IDA, GO:0005515=IPI, GO:0006461=NAS, GO:0006944=TAS, GO:0016020=IEA, GO:0050821=NAS, GO:0006891=TAS, GO:0006886=IEA} cellular membrane fusion, intra-Golgi vesicle-mediated transport, intracellular protein transport, protein complex assembly, protein stabilization membrane, mitochondrion protein binding Human NAPRT1 HPA UniProtKB {GO:0019358=GO_REF:0000002, GO:0005794=GO_REF:0000052, GO:0019674=Reactome:REACT_11088, GO:0006767=Reactome:REACT_11238, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0006769=Reactome:REACT_11213, GO:0005829=Reactome:REACT_11132, GO:0004516=Reactome:REACT_11132, GO:0005737=GO_REF:0000052, GO:0006766=Reactome:REACT_11193, GO:0004514=GO_REF:0000002, GO:0009435=GO_REF:0000041, GO:0006979=PMID:17604275} Q6XQN6 Nicotinate phosphoribosyltransferase protein 20101115 {GO:0019358=IEA, GO:0005794=IDA, GO:0019674=TAS, GO:0006767=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0006769=TAS, GO:0005829=TAS, GO:0004516=TAS, GO:0005737=IDA, GO:0006766=TAS, GO:0004514=IEA, GO:0009435=IEA, GO:0006979=IMP} NAD biosynthetic process, NAD metabolic process, nicotinamide metabolic process, nicotinate nucleotide salvage, response to oxidative stress, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process Golgi apparatus, cytoplasm, cytosol, nucleus nicotinate phosphoribosyltransferase activity, nicotinate-nucleotide diphosphorylase (carboxylating) activity Human NAPSA UniProtKB UniProtKB {GO:0004175=PMID:14766755, GO:0006508=PMID:9877162, GO:0043129=PMID:18216060, GO:0008233=PMID:18216060, GO:0004190=PMID:9877162} O96009 Napsin-A protein 20120713 {GO:0004175=IDA, GO:0006508=NAS, GO:0043129=IDA, GO:0008233=IDA, GO:0004190=NAS} proteolysis, surfactant homeostasis aspartic-type endopeptidase activity, endopeptidase activity, peptidase activity Human NARF HGNC UniProtKB {GO:0005652=PMID:10514485, GO:0031981=PMID:10514485, GO:0005638=PMID:10514485, GO:0005521=PMID:10514485} Q9UHQ1 Nuclear prelamin A recognition factor protein 20071001 {GO:0005652=TAS, GO:0031981=IDA, GO:0005638=IDA, GO:0005521=IPI} lamin filament, nuclear lamina, nuclear lumen lamin binding Human NARFL Reactome UniProtKB {GO:0001666=PMID:16956324, GO:0006355=PMID:16956324, GO:0051539=GO_REF:0000037, GO:0016226=PMID:18270200, GO:0097361=PMID:22678361, GO:0044281=Reactome:REACT_111217, GO:0032364=PMID:16956324, GO:0046872=GO_REF:0000037} Q9H6Q4 Cytosolic Fe-S cluster assembly factor NARFL protein 20121107 {GO:0001666=IDA, GO:0006355=IDA, GO:0051539=IEA, GO:0016226=IMP, GO:0097361=IDA, GO:0044281=TAS, GO:0032364=IDA, GO:0046872=IEA} iron-sulfur cluster assembly, oxygen homeostasis, regulation of transcription, DNA-dependent, response to hypoxia, small molecule metabolic process CIA complex 4 iron, 4 sulfur cluster binding, metal ion binding Human NARG2 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039} Q659A1 NMDA receptor-regulated protein 2 protein 20130413 {GO:0005634=IEA} nucleus Human UniProtKB-SubCell:SL-0191 NARS HPA UniProtKB {GO:0005739=GO_REF:0000019, GO:0010467=Reactome:REACT_71, GO:0005737=GO_REF:0000052, GO:0006421=GO_REF:0000002, GO:0004816=GO_REF:0000003, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0006418=Reactome:REACT_15482, GO:0005829=Reactome:REACT_15414} O43776 Asparagine--tRNA ligase, cytoplasmic protein 20111111 {GO:0005739=IEA, GO:0010467=TAS, GO:0005737=IDA, GO:0006421=IEA, GO:0004816=IEA, GO:0003676=IEA, GO:0005524=IEA, GO:0006418=TAS, GO:0005829=TAS} asparaginyl-tRNA aminoacylation, gene expression, tRNA aminoacylation for protein translation cytoplasm, cytosol, mitochondrion ATP binding, asparagine-tRNA ligase activity, nucleic acid binding Human NARS2 Reactome UniProtKB {GO:0005739=GO_REF:0000024, GO:0010467=Reactome:REACT_71, GO:0005737=GO_REF:0000002, GO:0005759=GO_REF:0000039, GO:0006421=GO_REF:0000024, GO:0004816=GO_REF:0000024, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0006418=Reactome:REACT_15482} Q96I59 Probable asparagine--tRNA ligase, mitochondrial protein 20130301 {GO:0005739=ISS, GO:0010467=TAS, GO:0005737=IEA, GO:0005759=IEA, GO:0006421=ISS, GO:0004816=ISS, GO:0003676=IEA, GO:0005524=IEA, GO:0006418=TAS} asparaginyl-tRNA aminoacylation, gene expression, tRNA aminoacylation for protein translation cytoplasm, mitochondrial matrix, mitochondrion ATP binding, asparagine-tRNA ligase activity, nucleic acid binding Human NASP UniProtKB UniProtKB {GO:0006260=GO_REF:0000024, GO:0042393=GO_REF:0000019, GO:0007049=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0043486=GO_REF:0000024, GO:0008283=GO_REF:0000024, GO:0001824=GO_REF:0000024, GO:0051879=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0015031=GO_REF:0000037} P49321 Nuclear autoantigenic sperm protein protein 20061122 {GO:0006260=ISS, GO:0042393=IEA, GO:0007049=ISS, GO:0005737=IEA, GO:0043486=ISS, GO:0008283=ISS, GO:0001824=ISS, GO:0051879=ISS, GO:0005634=ISS, GO:0015031=IEA} DNA replication, blastocyst development, cell cycle, cell proliferation, histone exchange, protein transport cytoplasm, nucleus Hsp90 protein binding, histone binding Human UniProtKB:Q99MD9 NAT1 Reactome UniProtKB {GO:0006805=Reactome:REACT_13433, GO:0004060=GO_REF:0000003, GO:0016407=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_6832} P18440 Arylamine N-acetyltransferase 1 protein 20130301 {GO:0006805=TAS, GO:0004060=IEA, GO:0016407=IEA, GO:0044281=TAS, GO:0005829=TAS} small molecule metabolic process, xenobiotic metabolic process cytosol acetyltransferase activity, arylamine N-acetyltransferase activity Human NAT10 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0008080=GO_REF:0000002, GO:0005730=GO_REF:0000039, GO:0005634=PMID:11214970, GO:0005524=GO_REF:0000037} Q9H0A0 N-acetyltransferase 10 protein 20021101 {GO:0008150=ND, GO:0003674=ND, GO:0008080=IEA, GO:0005730=IEA, GO:0005634=NAS, GO:0005524=IEA} biological_process nucleolus, nucleus ATP binding, N-acetyltransferase activity, molecular_function Human NAT14 UniProtKB UniProtKB {GO:0006352=PMID:10873651, GO:0008080=GO_REF:0000002, GO:0005634=PMID:10873651, GO:0016021=GO_REF:0000037, GO:0045893=PMID:10873651, GO:0003677=GO_REF:0000037} Q8WUY8 N-acetyltransferase 14 protein 20010829 {GO:0006352=NAS, GO:0008080=IEA, GO:0005634=NAS, GO:0016021=IEA, GO:0045893=NAS, GO:0003677=IEA} DNA-dependent transcription, initiation, positive regulation of transcription, DNA-dependent integral to membrane, nucleus DNA binding, N-acetyltransferase activity Human NAT16 InterPro UniProtKB {GO:0008080=GO_REF:0000002} Q8N8M0 Putative N-acetyltransferase 16 protein 20130413 {GO:0008080=IEA} N-acetyltransferase activity Human InterPro:IPR000182 NAT2 Reactome UniProtKB {GO:0006805=Reactome:REACT_13433, GO:0004060=GO_REF:0000003, GO:0016407=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_6944} P11245 Arylamine N-acetyltransferase 2 protein 20130301 {GO:0006805=TAS, GO:0004060=IEA, GO:0016407=IEA, GO:0044281=TAS, GO:0005829=TAS} small molecule metabolic process, xenobiotic metabolic process cytosol acetyltransferase activity, arylamine N-acetyltransferase activity Human NAT6 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0008080=GO_REF:0000002} Q93015 N-acetyltransferase 6 protein 20110516 {GO:0005739=IDA, GO:0005737=IDA, GO:0008080=IEA} cytoplasm, mitochondrion N-acetyltransferase activity Human NAT8 PINC UniProtKB {GO:0008080=PMID:11397015, GO:0042493=PMID:9852678, GO:0016021=PMID:11397015, GO:0001702=PMID:11397015} Q9UHE5 Probable N-acetyltransferase 8 protein 20070906 {GO:0008080=NAS, GO:0042493=TAS, GO:0016021=NAS, GO:0001702=IMP} gastrulation with mouth forming second, response to drug integral to membrane N-acetyltransferase activity Human NAT8B UniProtKB UniProtKB {GO:0008080=PMID:11397015, GO:0016021=PMID:11397015, GO:0001702=PMID:11397015} Q9UHF3 Probable N-acetyltransferase 8B protein 20070411 {GO:0008080=NAS, GO:0016021=NAS, GO:0001702=NAS} gastrulation with mouth forming second integral to membrane N-acetyltransferase activity Human NAT9 LIFEdb UniProtKB {GO:0043234=GO_REF:0000054, GO:0008080=GO_REF:0000002} Q9BTE0 N-acetyltransferase 9 protein 20100607 {GO:0043234=IDA, GO:0008080=IEA} protein complex N-acetyltransferase activity Human NAV1 ENSEMBL UniProtKB {GO:0005737=GO_REF:0000037, GO:0017111=GO_REF:0000002, GO:0000166=GO_REF:0000002, GO:0001578=GO_REF:0000019, GO:0005874=GO_REF:0000037, GO:0001764=GO_REF:0000019} Q8NEY1 Neuron navigator 1 protein 20130413 {GO:0005737=IEA, GO:0017111=IEA, GO:0000166=IEA, GO:0001578=IEA, GO:0005874=IEA, GO:0001764=IEA} microtubule bundle formation, neuron migration cytoplasm, microtubule nucleoside-triphosphatase activity, nucleotide binding Human Ensembl:ENSMUSP00000067241 NAV2 UniProtKB UniProtKB {GO:0007608=GO_REF:0000019, GO:0021554=GO_REF:0000019, GO:0007605=GO_REF:0000019, GO:0004386=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0007626=GO_REF:0000019, GO:0021564=GO_REF:0000019, GO:0005614=GO_REF:0000019, GO:0008201=GO_REF:0000019, GO:0003025=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0021563=GO_REF:0000019} Q8IVL1 Neuron navigator 2 protein 20130413 {GO:0007608=IEA, GO:0021554=IEA, GO:0007605=IEA, GO:0004386=IEA, GO:0005634=IEA, GO:0007626=IEA, GO:0021564=IEA, GO:0005614=IEA, GO:0008201=IEA, GO:0003025=IEA, GO:0005524=IEA, GO:0021563=IEA} glossopharyngeal nerve development, locomotory behavior, optic nerve development, regulation of systemic arterial blood pressure by baroreceptor feedback, sensory perception of smell, sensory perception of sound, vagus nerve development interstitial matrix, nucleus ATP binding, helicase activity, heparin binding Human UniProtKB-SubCell:SL-0191 NAV3 UniProtKB UniProtKB {GO:0005640=GO_REF:0000039, GO:0017111=GO_REF:0000002, GO:0000166=GO_REF:0000002, GO:0005635=GO_REF:0000019} Q8IVL0 Neuron navigator 3 protein 20130413 {GO:0005640=IEA, GO:0017111=IEA, GO:0000166=IEA, GO:0005635=IEA} nuclear envelope, nuclear outer membrane nucleoside-triphosphatase activity, nucleotide binding Human UniProtKB-SubCell:SL-0183 NBAS UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} A2RRP1 Neuroblastoma-amplified sequence protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 NBEA UniProtKB UniProtKB {GO:0005802=GO_REF:0000024, GO:0008104=GO_REF:0000019, GO:0005886=GO_REF:0000024, GO:0019901=GO_REF:0000019, GO:0012505=GO_REF:0000024, GO:0005829=GO_REF:0000024} Q8NFP9 Neurobeachin protein 20041006 {GO:0005802=ISS, GO:0008104=IEA, GO:0005886=ISS, GO:0019901=IEA, GO:0012505=ISS, GO:0005829=ISS} protein localization cytosol, endomembrane system, plasma membrane, trans-Golgi network protein kinase binding Human UniProtKB:Q9EPN1 NBEAL1 null null {} null null null null {} null null null NBEAL2 UniProtKB UniProtKB {GO:0005783=PMID:21765412, GO:0030220=PMID:21765411} Q6ZNJ1 Neurobeachin-like protein 2 protein 20111207 {GO:0005783=IDA, GO:0030220=IMP} platelet formation endoplasmic reticulum Human NBL1 BHF-UCL UniProtKB {GO:0016015=GO_REF:0000024, GO:0045666=GO_REF:0000019, GO:0036122=GO_REF:0000024, GO:0035582=GO_REF:0000024, GO:0048812=GO_REF:0000024, GO:0048263=GO_REF:0000024, GO:0005576=GO_REF:0000039, GO:0090027=GO_REF:0000024, GO:0007399=GO_REF:0000024} P41271 Neuroblastoma suppressor of tumorigenicity 1 protein 20120221 {GO:0016015=ISS, GO:0045666=IEA, GO:0036122=ISS, GO:0035582=ISS, GO:0048812=ISS, GO:0048263=ISS, GO:0005576=IEA, GO:0090027=ISS, GO:0007399=ISS} determination of dorsal identity, negative regulation of monocyte chemotaxis, nervous system development, neuron projection morphogenesis, positive regulation of neuron differentiation, sequestering of BMP in extracellular matrix extracellular region BMP binding, morphogen activity Human UniProtKB:Q61477 NBN BHF-UCL UniProtKB {GO:0007095=PMID:11438675, GO:0005515=PMID:18001825, GO:0007093=PMID:10766245, GO:0030870=PMID:19151086, GO:0008283=GO_REF:0000019, GO:0005657=GO_REF:0000019, GO:0001832=GO_REF:0000019, GO:0005634=PMID:10888888, GO:0006302=Reactome:REACT_2054, GO:0004003=PMID:15790808, GO:0000723=PMID:11448772, GO:0000724=Reactome:REACT_1874, GO:0050885=GO_REF:0000019, GO:0007050=PMID:9590181, GO:0032508=PMID:15790808, GO:0000784=PMID:10888888, GO:0031954=PMID:15790808, GO:0033674=PMID:15790808, GO:0030330=PMID:9590181, GO:0045190=GO_REF:0000019, GO:0005730=PMID:10888888, GO:0006915=GO_REF:0000019, GO:0003684=PMID:9590180, GO:0030174=PMID:9590181, GO:0006281=Reactome:REACT_216, GO:0007126=GO_REF:0000037, GO:0047485=PMID:9590181, GO:0016605=PMID:12470659, GO:0005654=Reactome:REACT_2009, GO:0000077=PMID:12529385, GO:0008134=PMID:11486038, GO:0042405=PMID:12447371} O60934 Nibrin protein 20081217 {GO:0007095=IDA, GO:0005515=IPI, GO:0007093=IDA, GO:0030870=IDA, GO:0008283=IEA, GO:0005657=IEA, GO:0001832=IEA, GO:0005634=IDA, GO:0006302=TAS, GO:0004003=IMP, GO:0000723=IMP, GO:0000724=TAS, GO:0050885=IEA, GO:0007050=TAS, GO:0032508=IMP, GO:0000784=IDA, GO:0031954=IDA, GO:0033674=IDA, GO:0030330=TAS, GO:0045190=IEA, GO:0005730=IDA, GO:0006915=IEA, GO:0003684=IC, GO:0030174=TAS, GO:0006281=TAS, GO:0007126=IEA, GO:0047485=IPI, GO:0016605=IDA, GO:0005654=TAS, GO:0000077=IDA, GO:0008134=IPI, GO:0042405=IDA} DNA damage checkpoint, DNA damage response, signal transduction by p53 class mediator, DNA duplex unwinding, DNA repair, apoptotic process, blastocyst growth, cell cycle arrest, cell proliferation, double-strand break repair, double-strand break repair via homologous recombination, isotype switching, meiosis, mitotic G2 DNA damage checkpoint, mitotic cell cycle checkpoint, neuromuscular process controlling balance, positive regulation of kinase activity, positive regulation of protein autophosphorylation, regulation of DNA-dependent DNA replication initiation, telomere maintenance Mre11 complex, PML body, nuclear chromosome, telomeric region, nuclear inclusion body, nucleolus, nucleoplasm, nucleus, replication fork ATP-dependent DNA helicase activity, damaged DNA binding, protein N-terminus binding, protein binding, transcription factor binding Human NBPF1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q3BBV0 Neuroblastoma breakpoint family member 1 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 NBPF10 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q6P3W6 Neuroblastoma breakpoint family member 10 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 NBPF11 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q86T75 Neuroblastoma breakpoint family member 11 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 NBPF12 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q5TAG4 Neuroblastoma breakpoint family member 12 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 NBPF14 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q5TI25 Neuroblastoma breakpoint family member 14 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 NBPF15 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q8N660 Neuroblastoma breakpoint family member 15 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 NBPF16 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q5SXJ2 Neuroblastoma breakpoint family member 16 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 NBPF24 null null {} null null null null {} null null null NBPF3 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q9H094 Neuroblastoma breakpoint family member 3 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 NBPF9 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q3BBW0 Neuroblastoma breakpoint family member 9 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 NBR1 BHF-UCL UniProtKB {GO:0005515=PMID:20562859, GO:0043130=PMID:19427866, GO:0030500=GO_REF:0000024, GO:0005776=GO_REF:0000024, GO:0005770=GO_REF:0000024, GO:0016236=PMID:19250911, GO:0031410=GO_REF:0000037, GO:0000407=GO_REF:0000019, GO:0032872=GO_REF:0000024, GO:0005764=GO_REF:0000039, GO:0031430=GO_REF:0000039, GO:0051259=PMID:19250911, GO:0005829=PMID:19250911, GO:0045668=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0051019=GO_REF:0000024} Q14596 Next to BRCA1 gene 1 protein protein 20110713 {GO:0005515=IPI, GO:0043130=IDA, GO:0030500=ISS, GO:0005776=ISS, GO:0005770=ISS, GO:0016236=IDA, GO:0031410=IEA, GO:0000407=IEA, GO:0032872=ISS, GO:0005764=IEA, GO:0031430=IEA, GO:0051259=IDA, GO:0005829=IDA, GO:0045668=ISS, GO:0008270=IEA, GO:0051019=ISS} macroautophagy, negative regulation of osteoblast differentiation, protein oligomerization, regulation of bone mineralization, regulation of stress-activated MAPK cascade M band, autophagic vacuole, cytoplasmic vesicle, cytosol, late endosome, lysosome, pre-autophagosomal structure mitogen-activated protein kinase binding, protein binding, ubiquitin binding, zinc ion binding Human UniProtKB:P97432 NCALD LIFEdb UniProtKB {GO:0005622=GO_REF:0000054, GO:0015631=PMID:11964161, GO:0030276=PMID:11964161, GO:0043014=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0030130=PMID:11964161, GO:0003779=PMID:11964161, GO:0016192=PMID:11964161, GO:0005829=Reactome:REACT_21414} P61601 Neurocalcin-delta protein 20100607 {GO:0005622=IDA, GO:0015631=IDA, GO:0030276=IDA, GO:0043014=IEA, GO:0005509=IEA, GO:0007268=TAS, GO:0030130=NAS, GO:0003779=IDA, GO:0016192=NAS, GO:0005829=TAS} synaptic transmission, vesicle-mediated transport clathrin coat of trans-Golgi network vesicle, cytosol, intracellular actin binding, alpha-tubulin binding, calcium ion binding, clathrin binding, tubulin binding Human NCAM1 BHF-UCL UniProtKB {GO:0030424=GO_REF:0000019, GO:0009986=PMID:10766765, GO:0005886=Reactome:REACT_25082, GO:0019221=Reactome:REACT_25229, GO:0005576=GO_REF:0000039, GO:0031225=GO_REF:0000037, GO:0030426=GO_REF:0000019, GO:0050850=GO_REF:0000019, GO:0001928=GO_REF:0000019, GO:0034109=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0000139=Reactome:REACT_18324, GO:0007411=Reactome:REACT_18266, GO:0043025=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007155=PMID:10770948, GO:0009897=PMID:17213291, GO:0060333=Reactome:REACT_25078} P13591 Neural cell adhesion molecule 1 protein 20110720 {GO:0030424=IEA, GO:0009986=IDA, GO:0005886=TAS, GO:0019221=TAS, GO:0005576=IEA, GO:0031225=IEA, GO:0030426=IEA, GO:0050850=IEA, GO:0001928=IEA, GO:0034109=IEA, GO:0016020=IEA, GO:0000139=TAS, GO:0007411=TAS, GO:0043025=IEA, GO:0016021=IEA, GO:0007155=NAS, GO:0009897=IDA, GO:0060333=TAS} axon guidance, cell adhesion, cytokine-mediated signaling pathway, homotypic cell-cell adhesion, interferon-gamma-mediated signaling pathway, positive regulation of calcium-mediated signaling, regulation of exocyst assembly Golgi membrane, anchored to membrane, axon, cell surface, external side of plasma membrane, extracellular region, growth cone, integral to membrane, membrane, neuronal cell body, plasma membrane Human NCAM2 PINC UniProtKB {GO:0030424=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000002, GO:0007158=PMID:9226371} O15394 Neural cell adhesion molecule 2 protein 20030904 {GO:0030424=IEA, GO:0005886=IEA, GO:0016020=IEA, GO:0016021=IEA, GO:0007155=IEA, GO:0007158=TAS} cell adhesion, neuron cell-cell adhesion axon, integral to membrane, membrane, plasma membrane Human NCAN Reactome UniProtKB {GO:0005796=Reactome:REACT_121341, GO:0005975=Reactome:REACT_474, GO:0005509=GO_REF:0000002, GO:0005576=Reactome:REACT_121341, GO:0044281=Reactome:REACT_111217, GO:0030208=Reactome:REACT_120800, GO:0030207=Reactome:REACT_120888, GO:0051823=GO_REF:0000019, GO:0030206=Reactome:REACT_120989, GO:0005540=GO_REF:0000037, GO:0007411=Reactome:REACT_18266, GO:0030246=GO_REF:0000002, GO:0007155=GO_REF:0000037, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408, GO:0043202=Reactome:REACT_121272} O14594 Neurocan core protein protein 20130301 {GO:0005796=TAS, GO:0005975=TAS, GO:0005509=IEA, GO:0005576=TAS, GO:0044281=TAS, GO:0030208=TAS, GO:0030207=TAS, GO:0051823=IEA, GO:0030206=TAS, GO:0005540=IEA, GO:0007411=TAS, GO:0030246=IEA, GO:0007155=IEA, GO:0030204=TAS, GO:0030203=TAS, GO:0043202=TAS} axon guidance, carbohydrate metabolic process, cell adhesion, chondroitin sulfate biosynthetic process, chondroitin sulfate catabolic process, chondroitin sulfate metabolic process, dermatan sulfate biosynthetic process, glycosaminoglycan metabolic process, regulation of synapse structural plasticity, small molecule metabolic process Golgi lumen, extracellular region, lysosomal lumen calcium ion binding, carbohydrate binding, hyaluronic acid binding Human NCAPD2 HPA UniProtKB {GO:0000796=PMID:11136719, GO:0005515=PMID:12138188, GO:0000236=Reactome:REACT_682, GO:0007076=PMID:11136719, GO:0000793=PMID:10101332, GO:0000797=PMID:10958694, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000228=PMID:12138188, GO:0005829=Reactome:REACT_150403, GO:0042393=PMID:12138188, GO:0005737=GO_REF:0000052, GO:0000087=Reactome:REACT_910, GO:0045120=GO_REF:0000019, GO:0000278=Reactome:REACT_152, GO:0051301=GO_REF:0000037} Q15021 Condensin complex subunit 1 protein 20111111 {GO:0000796=IDA, GO:0005515=IPI, GO:0000236=TAS, GO:0007076=IDA, GO:0000793=IDA, GO:0000797=NAS, GO:0005730=IDA, GO:0005634=IDA, GO:0000228=IDA, GO:0005829=TAS, GO:0042393=IDA, GO:0005737=IDA, GO:0000087=TAS, GO:0045120=IEA, GO:0000278=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, cell division, mitotic cell cycle, mitotic chromosome condensation, mitotic prometaphase condensed chromosome, condensin complex, condensin core heterodimer, cytoplasm, cytosol, nuclear chromosome, nucleolus, nucleus, pronucleus histone binding, protein binding Human NCAPD3 BHF-UCL UniProtKB {GO:0007076=PMID:14532007, GO:0000799=PMID:14532007, GO:0035064=PMID:20622854, GO:0031618=PMID:20551165, GO:0051301=GO_REF:0000037} P42695 Condensin-2 complex subunit D3 protein 20110307 {GO:0007076=IDA, GO:0000799=IDA, GO:0035064=IDA, GO:0031618=IDA, GO:0051301=IEA} cell division, mitotic chromosome condensation nuclear centromeric heterochromatin, nuclear condensin complex methylated histone residue binding Human NCAPG HPA UniProtKB {GO:0005515=PMID:12138188, GO:0000796=PMID:11136719, GO:0000236=Reactome:REACT_682, GO:0007076=PMID:11136719, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0000087=Reactome:REACT_910, GO:0005634=PMID:10910072, GO:0015629=GO_REF:0000052, GO:0000278=Reactome:REACT_152, GO:0005829=Reactome:REACT_150403, GO:0051301=GO_REF:0000037} Q9BPX3 Condensin complex subunit 3 protein 20111111 {GO:0005515=IPI, GO:0000796=IDA, GO:0000236=TAS, GO:0007076=IDA, GO:0005813=IDA, GO:0005737=IDA, GO:0000087=TAS, GO:0005634=NAS, GO:0015629=IDA, GO:0000278=TAS, GO:0005829=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, cell division, mitotic cell cycle, mitotic chromosome condensation, mitotic prometaphase actin cytoskeleton, centrosome, condensin complex, cytoplasm, cytosol, nucleus protein binding Human NCAPG2 HPA UniProtKB {GO:0007067=GO_REF:0000037, GO:0030261=GO_REF:0000037, GO:0001833=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0035064=PMID:20622854, GO:0051301=GO_REF:0000037} Q86XI2 Condensin-2 complex subunit G2 protein 20101115 {GO:0007067=IEA, GO:0030261=IEA, GO:0001833=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0035064=IDA, GO:0051301=IEA} cell division, chromosome condensation, inner cell mass cell proliferation, mitosis nucleolus, nucleus methylated histone residue binding NOT Human NCAPH HPA UniProtKB {GO:0000796=PMID:11136719, GO:0005515=PMID:21730191, GO:0007076=PMID:11136719, GO:0000236=Reactome:REACT_682, GO:0030261=GO_REF:0000038, GO:0005634=GO_REF:0000039, GO:0005829=Reactome:REACT_150403, GO:0005737=GO_REF:0000052, GO:0007067=GO_REF:0000038, GO:0015630=GO_REF:0000052, GO:0000087=Reactome:REACT_910, GO:0000278=Reactome:REACT_152, GO:0051301=GO_REF:0000037} Q15003 Condensin complex subunit 2 protein 20101115 {GO:0000796=IDA, GO:0005515=IPI, GO:0007076=IDA, GO:0000236=TAS, GO:0030261=IEA, GO:0005634=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0007067=IEA, GO:0015630=IDA, GO:0000087=TAS, GO:0000278=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, cell division, chromosome condensation, mitosis, mitotic cell cycle, mitotic chromosome condensation, mitotic prometaphase condensin complex, cytoplasm, cytosol, microtubule cytoskeleton, nucleus protein binding Human NCAPH2 UniProtKB UniProtKB {GO:0005694=GO_REF:0000039, GO:0030261=GO_REF:0000037, GO:0005634=GO_REF:0000039} Q6IBW4 Condensin-2 complex subunit H2 protein 20130413 {GO:0005694=IEA, GO:0030261=IEA, GO:0005634=IEA} chromosome condensation chromosome, nucleus Human UniProtKB-SubCell:SL-0468 NCBP1 IntAct UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:18423201, GO:0000339=GO_REF:0000002, GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0006368=Reactome:REACT_1845, GO:0006366=Reactome:REACT_1366, GO:0003723=PMID:8069914, GO:0031124=Reactome:REACT_1849, GO:0005634=PMID:9342333, GO:0031047=GO_REF:0000037, GO:0005829=Reactome:REACT_75917, GO:0006406=Reactome:REACT_1597, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6256, GO:0006379=PMID:9342333, GO:0016070=Reactome:REACT_21257, GO:0008334=Reactome:REACT_1364, GO:0016071=Reactome:REACT_20605, GO:0045292=GO_REF:0000002, GO:0006370=Reactome:REACT_1470, GO:0034660=Reactome:REACT_11052, GO:0000387=Reactome:REACT_11066, GO:0003677=GO_REF:0000002, GO:0050434=Reactome:REACT_6162, GO:0000398=Reactome:REACT_1753, GO:0030529=PMID:17289661, GO:0006446=PMID:11551508, GO:0005654=Reactome:REACT_10069, GO:0051028=GO_REF:0000002, GO:0005845=PMID:9342333, GO:0005846=GO_REF:0000002, GO:0031442=PMID:9342333} Q09161 Nuclear cap-binding protein subunit 1 protein 20130415 {GO:0008380=TAS, GO:0005515=IPI, GO:0000339=IEA, GO:0022415=TAS, GO:0010467=TAS, GO:0006369=TAS, GO:0006368=TAS, GO:0006366=TAS, GO:0003723=TAS, GO:0031124=TAS, GO:0005634=IDA, GO:0031047=IEA, GO:0005829=TAS, GO:0006406=TAS, GO:0000184=TAS, GO:0016032=TAS, GO:0006379=IDA, GO:0016070=TAS, GO:0008334=TAS, GO:0016071=TAS, GO:0045292=IEA, GO:0006370=TAS, GO:0034660=TAS, GO:0000387=TAS, GO:0003677=IEA, GO:0050434=TAS, GO:0000398=TAS, GO:0030529=IDA, GO:0006446=IDA, GO:0005654=TAS, GO:0051028=IEA, GO:0005845=IDA, GO:0005846=IEA, GO:0031442=IDA} 7-methylguanosine mRNA capping, RNA metabolic process, RNA splicing, gene expression, gene silencing by RNA, histone mRNA metabolic process, mRNA 3'-end processing, mRNA cis splicing, via spliceosome, mRNA cleavage, mRNA export from nucleus, mRNA metabolic process, mRNA splicing, via spliceosome, mRNA transport, ncRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, positive regulation of mRNA 3'-end processing, positive regulation of viral transcription, regulation of translational initiation, spliceosomal snRNP assembly, termination of RNA polymerase II transcription, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, viral reproduction, viral reproductive process cytosol, mRNA cap binding complex, nuclear cap binding complex, nucleoplasm, nucleus, ribonucleoprotein complex DNA binding, RNA binding, RNA cap binding, protein binding Human UniProtKB:Q9BY77 NCBP2 HPA UniProtKB {GO:0000339=PMID:7651522, GO:0005515=PMID:12434151, GO:0008380=Reactome:REACT_1735, GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0006368=Reactome:REACT_1845, GO:0006366=Reactome:REACT_1366, GO:0003723=PMID:7478990, GO:0031124=Reactome:REACT_1849, GO:0005634=GO_REF:0000052, GO:0031047=GO_REF:0000037, GO:0005829=Reactome:REACT_75917, GO:0005737=PMID:8601613, GO:0006406=Reactome:REACT_1597, GO:0000184=Reactome:REACT_75886, GO:0000166=GO_REF:0000002, GO:0006408=GO_REF:0000024, GO:0016032=Reactome:REACT_6256, GO:0000340=PMID:18426921, GO:0016070=Reactome:REACT_21257, GO:0008334=Reactome:REACT_1364, GO:0016071=Reactome:REACT_20605, GO:0045292=PMID:18426921, GO:0005730=GO_REF:0000052, GO:0006370=Reactome:REACT_1470, GO:0034660=Reactome:REACT_11052, GO:0000387=Reactome:REACT_11066, GO:0050434=Reactome:REACT_6162, GO:0000398=Reactome:REACT_1753, GO:0006446=PMID:11551508, GO:0005654=Reactome:REACT_10069, GO:0046833=GO_REF:0000024, GO:0005845=PMID:9342333, GO:0005846=GO_REF:0000002} P52298 Nuclear cap-binding protein subunit 2 protein 20111111 {GO:0000339=NAS, GO:0005515=IPI, GO:0008380=TAS, GO:0022415=TAS, GO:0010467=TAS, GO:0006369=TAS, GO:0006368=TAS, GO:0006366=TAS, GO:0003723=IDA, GO:0031124=TAS, GO:0005634=IDA, GO:0031047=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0006406=TAS, GO:0000184=TAS, GO:0000166=IEA, GO:0006408=ISS, GO:0016032=TAS, GO:0000340=IDA, GO:0016070=TAS, GO:0008334=TAS, GO:0016071=TAS, GO:0045292=IDA, GO:0005730=IDA, GO:0006370=TAS, GO:0034660=TAS, GO:0000387=TAS, GO:0050434=TAS, GO:0000398=TAS, GO:0006446=IDA, GO:0005654=TAS, GO:0046833=ISS, GO:0005845=IDA, GO:0005846=IEA} 7-methylguanosine mRNA capping, RNA metabolic process, RNA splicing, gene expression, gene silencing by RNA, histone mRNA metabolic process, mRNA 3'-end processing, mRNA cis splicing, via spliceosome, mRNA export from nucleus, mRNA metabolic process, mRNA splicing, via spliceosome, ncRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, positive regulation of RNA export from nucleus, positive regulation of viral transcription, regulation of translational initiation, snRNA export from nucleus, spliceosomal snRNP assembly, termination of RNA polymerase II transcription, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, viral reproduction, viral reproductive process cytoplasm, cytosol, mRNA cap binding complex, nuclear cap binding complex, nucleolus, nucleoplasm, nucleus RNA 7-methylguanosine cap binding, RNA binding, RNA cap binding, nucleotide binding, protein binding NOT Human NCCRP1 UniProtKB UniProtKB {GO:0030163=GO_REF:0000002, GO:0005737=PMID:22087255, GO:0008284=PMID:22087255} Q6ZVX7 F-box only protein 50 protein 20121121 {GO:0030163=IEA, GO:0005737=IDA, GO:0008284=IDA} positive regulation of cell proliferation, protein catabolic process cytoplasm Human NCDN UniProtKB UniProtKB {GO:0030424=GO_REF:0000024, GO:0048168=GO_REF:0000019, GO:0045453=GO_REF:0000019, GO:0043025=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0031175=GO_REF:0000024, GO:0030425=GO_REF:0000024, GO:0005829=GO_REF:0000024} Q9UBB6 Neurochondrin protein 20100426 {GO:0030424=ISS, GO:0048168=IEA, GO:0045453=IEA, GO:0043025=ISS, GO:0005634=ISS, GO:0031175=ISS, GO:0030425=ISS, GO:0005829=ISS} bone resorption, neuron projection development, regulation of neuronal synaptic plasticity axon, cytosol, dendrite, neuronal cell body, nucleus Human UniProtKB:O35095 NCF1 GOC UniProtKB {GO:0045730=PMID:7938008, GO:0005515=PMID:11733522, GO:0002474=Reactome:REACT_75820, GO:0017124=PMID:7938008, GO:0008283=GO_REF:0000019, GO:0006801=PMID:7938008, GO:0003924=PMID:2547247, GO:0050665=GO_REF:0000019, GO:0006691=GO_REF:0000019, GO:0001878=GO_REF:0000019, GO:0005829=Reactome:REACT_121023, GO:0002679=GO_REF:0000019, GO:0005737=GO_REF:0000002, GO:0006954=GO_REF:0000019, GO:0007154=GO_REF:0000002, GO:0045986=GO_REF:0000019, GO:0016175=GO_REF:0000002, GO:0006612=PMID:12356722, GO:0032010=Reactome:REACT_111243, GO:0090382=Reactome:REACT_121256, GO:0070947=GO_REF:0000019, GO:0070946=GO_REF:0000019, GO:0042554=PMID:7938008, GO:0051701=Reactome:REACT_121237, GO:0042590=Reactome:REACT_111119, GO:0009055=PMID:2848318, GO:0005525=PMID:2848318, GO:0006184=PMID:2547247, GO:0006968=GO_REF:0000019, GO:0045087=PMID:7938008, GO:0002479=Reactome:REACT_111174, GO:0043020=PMID:7938008, GO:0035091=PMID:12356722} P14598 Neutrophil cytosol factor 1 protein 20130413 {GO:0045730=TAS, GO:0005515=IPI, GO:0002474=TAS, GO:0017124=IPI, GO:0008283=IEA, GO:0006801=TAS, GO:0003924=TAS, GO:0050665=IEA, GO:0006691=IEA, GO:0001878=IEA, GO:0005829=TAS, GO:0002679=IEA, GO:0005737=IEA, GO:0006954=IEA, GO:0007154=IEA, GO:0045986=IEA, GO:0016175=IEA, GO:0006612=IDA, GO:0032010=TAS, GO:0090382=TAS, GO:0070947=IEA, GO:0070946=IEA, GO:0042554=TAS, GO:0051701=TAS, GO:0042590=TAS, GO:0009055=TAS, GO:0005525=TAS, GO:0006184=TAS, GO:0006968=IEA, GO:0045087=TAS, GO:0002479=TAS, GO:0043020=TAS, GO:0035091=IDA} GTP catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, cell communication, cell proliferation, cellular defense response, hydrogen peroxide biosynthetic process, inflammatory response, innate immune response, interaction with host, leukotriene metabolic process, negative regulation of smooth muscle contraction, neutrophil mediated killing of fungus, neutrophil mediated killing of gram-positive bacterium, phagosome maturation, protein targeting to membrane, respiratory burst, respiratory burst involved in defense response, response to yeast, superoxide anion generation, superoxide metabolic process NADPH oxidase complex, cytoplasm, cytosol, phagolysosome GTP binding, GTPase activity, SH3 domain binding, electron carrier activity, phosphatidylinositol binding, protein binding, superoxide-generating NADPH oxidase activity Human NCF2 HPA UniProtKB {GO:0045730=PMID:7938008, GO:0005515=PMID:7938008, GO:0002474=Reactome:REACT_75820, GO:0006801=PMID:7938008, GO:0045777=GO_REF:0000019, GO:0032870=GO_REF:0000019, GO:0005829=Reactome:REACT_121023, GO:0005737=GO_REF:0000052, GO:0043525=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0032010=Reactome:REACT_111243, GO:0090382=Reactome:REACT_121256, GO:0042554=PMID:7938008, GO:0014823=GO_REF:0000019, GO:0001669=GO_REF:0000019, GO:0051701=Reactome:REACT_121237, GO:0042493=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0042590=Reactome:REACT_111119, GO:0009055=PMID:1692159, GO:0008022=PMID:9365277, GO:0009749=GO_REF:0000019, GO:0048365=GO_REF:0000019, GO:0006968=PMID:1692159, GO:0016020=GO_REF:0000019, GO:0045087=PMID:7938008, GO:0034616=GO_REF:0000019, GO:0055093=GO_REF:0000019, GO:0032570=GO_REF:0000019, GO:0002479=Reactome:REACT_111174, GO:0043020=PMID:7938008} P19878 Neutrophil cytosol factor 2 protein 20080205 {GO:0045730=TAS, GO:0005515=IPI, GO:0002474=TAS, GO:0006801=TAS, GO:0045777=IEA, GO:0032870=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0043525=IEA, GO:0032496=IEA, GO:0032010=TAS, GO:0090382=TAS, GO:0042554=TAS, GO:0014823=IEA, GO:0001669=IEA, GO:0051701=TAS, GO:0042493=IEA, GO:0007568=IEA, GO:0005730=IDA, GO:0042590=TAS, GO:0009055=TAS, GO:0008022=IPI, GO:0009749=IEA, GO:0048365=IEA, GO:0006968=TAS, GO:0016020=IEA, GO:0045087=TAS, GO:0034616=IEA, GO:0055093=IEA, GO:0032570=IEA, GO:0002479=TAS, GO:0043020=TAS} aging, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, cellular defense response, cellular response to hormone stimulus, innate immune response, interaction with host, phagosome maturation, positive regulation of blood pressure, positive regulation of neuron apoptotic process, respiratory burst, response to activity, response to drug, response to glucose stimulus, response to hyperoxia, response to laminar fluid shear stress, response to lipopolysaccharide, response to progesterone stimulus, superoxide anion generation, superoxide metabolic process NADPH oxidase complex, acrosomal vesicle, cytoplasm, cytosol, membrane, nucleolus, phagolysosome Rac GTPase binding, electron carrier activity, protein C-terminus binding, protein binding Human NCF4 Reactome UniProtKB {GO:0005515=PMID:9365277, GO:0002474=Reactome:REACT_75820, GO:0051701=Reactome:REACT_121237, GO:0042590=Reactome:REACT_111119, GO:0005829=Reactome:REACT_121023, GO:0005737=GO_REF:0000019, GO:0006955=PMID:8280052, GO:0007154=GO_REF:0000002, GO:0016020=PMID:8280052, GO:0046983=PMID:8280052, GO:0002479=Reactome:REACT_111174, GO:0043020=PMID:8280052, GO:0032010=Reactome:REACT_111243, GO:0035091=GO_REF:0000002, GO:0090382=Reactome:REACT_121256, GO:0055114=PMID:8839867} Q15080 Neutrophil cytosol factor 4 protein 20110228 {GO:0005515=IPI, GO:0002474=TAS, GO:0051701=TAS, GO:0042590=TAS, GO:0005829=TAS, GO:0005737=IEA, GO:0006955=TAS, GO:0007154=IEA, GO:0016020=IDA, GO:0046983=TAS, GO:0002479=TAS, GO:0043020=IDA, GO:0032010=TAS, GO:0035091=IEA, GO:0090382=TAS, GO:0055114=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, cell communication, immune response, interaction with host, oxidation-reduction process, phagosome maturation NADPH oxidase complex, cytoplasm, cytosol, membrane, phagolysosome phosphatidylinositol binding, protein binding, protein dimerization activity Human NCK1 IntAct UniProtKB {GO:0005515=PMID:22074159, GO:0012506=GO_REF:0000019, GO:0050852=Reactome:REACT_12526, GO:0005886=Reactome:REACT_118781, GO:0005783=GO_REF:0000039, GO:0019904=GO_REF:0000019, GO:0030032=GO_REF:0000019, GO:0005102=PMID:12110186, GO:0030159=PMID:12110186, GO:0005634=GO_REF:0000039, GO:0006417=GO_REF:0000037, GO:0005829=Reactome:REACT_160291, GO:0005737=PMID:12110186, GO:0042110=PMID:12110186, GO:0007172=PMID:12110186, GO:0016477=GO_REF:0000019, GO:0030838=PMID:12110186, GO:0007411=Reactome:REACT_18266, GO:0045087=Reactome:REACT_6802, GO:0045944=PMID:10026169, GO:0042102=PMID:12110186, GO:0007015=GO_REF:0000019, GO:0038096=Reactome:REACT_160123, GO:0008093=PMID:12110186} P16333 Cytoplasmic protein NCK1 protein 20130415 {GO:0005515=IPI, GO:0012506=IEA, GO:0050852=TAS, GO:0005886=TAS, GO:0005783=IEA, GO:0019904=IEA, GO:0030032=IEA, GO:0005102=IPI, GO:0030159=NAS, GO:0005634=IEA, GO:0006417=IEA, GO:0005829=TAS, GO:0005737=NAS, GO:0042110=IMP, GO:0007172=NAS, GO:0016477=IEA, GO:0030838=IMP, GO:0007411=TAS, GO:0045087=TAS, GO:0045944=IDA, GO:0042102=IMP, GO:0007015=IEA, GO:0038096=TAS, GO:0008093=NAS} Fc-gamma receptor signaling pathway involved in phagocytosis, T cell activation, T cell receptor signaling pathway, actin filament organization, axon guidance, cell migration, innate immune response, lamellipodium assembly, positive regulation of T cell proliferation, positive regulation of actin filament polymerization, positive regulation of transcription from RNA polymerase II promoter, regulation of translation, signal complex assembly cytoplasm, cytosol, endoplasmic reticulum, nucleus, plasma membrane, vesicle membrane cytoskeletal adaptor activity, protein binding, protein domain specific binding, receptor binding, receptor signaling complex scaffold activity Human UniProtKB:O15117 NCK2 IntAct UniProtKB {GO:0012506=GO_REF:0000019, GO:0005515=PMID:18086875, GO:0008285=PMID:9737977, GO:0005783=GO_REF:0000039, GO:0030032=GO_REF:0000019, GO:0030159=PMID:12110186, GO:0006417=GO_REF:0000037, GO:0005829=Reactome:REACT_23852, GO:0007165=PMID:9737977, GO:0005737=PMID:12110186, GO:0042110=PMID:12110186, GO:0007172=PMID:12110186, GO:0016477=GO_REF:0000019, GO:0007173=PMID:9737977, GO:0030838=PMID:12110186, GO:0007411=Reactome:REACT_18266, GO:0045944=PMID:10026169, GO:0007176=PMID:9737977, GO:0042102=PMID:12110186, GO:0007015=GO_REF:0000019, GO:0008093=PMID:12110186} O43639 Cytoplasmic protein NCK2 protein 20130415 {GO:0012506=IEA, GO:0005515=IPI, GO:0008285=TAS, GO:0005783=IEA, GO:0030032=IEA, GO:0030159=NAS, GO:0006417=IEA, GO:0005829=TAS, GO:0007165=TAS, GO:0005737=NAS, GO:0042110=NAS, GO:0007172=NAS, GO:0016477=IEA, GO:0007173=TAS, GO:0030838=IMP, GO:0007411=TAS, GO:0045944=IDA, GO:0007176=TAS, GO:0042102=IMP, GO:0007015=IEA, GO:0008093=NAS} T cell activation, actin filament organization, axon guidance, cell migration, epidermal growth factor receptor signaling pathway, lamellipodium assembly, negative regulation of cell proliferation, positive regulation of T cell proliferation, positive regulation of actin filament polymerization, positive regulation of transcription from RNA polymerase II promoter, regulation of epidermal growth factor-activated receptor activity, regulation of translation, signal complex assembly, signal transduction cytoplasm, cytosol, endoplasmic reticulum, vesicle membrane cytoskeletal adaptor activity, protein binding, receptor signaling complex scaffold activity Human UniProtKB:Q7L0Q8 NCKAP1 IntAct UniProtKB {GO:0005515=PMID:15296760, GO:0001756=GO_REF:0000019, GO:0030032=GO_REF:0000019, GO:0048570=GO_REF:0000019, GO:0005829=Reactome:REACT_160291, GO:0032880=GO_REF:0000019, GO:0008078=GO_REF:0000019, GO:0010172=GO_REF:0000019, GO:0035050=GO_REF:0000019, GO:0030950=GO_REF:0000019, GO:0031258=GO_REF:0000039, GO:0007354=GO_REF:0000019, GO:0050821=GO_REF:0000019, GO:0001843=GO_REF:0000019, GO:0006915=PMID:10673335, GO:0045176=GO_REF:0000019, GO:0045175=GO_REF:0000019, GO:0007417=PMID:10673335, GO:0001701=GO_REF:0000019, GO:0007492=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0048617=GO_REF:0000019, GO:0048340=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0038096=Reactome:REACT_160123} Q9Y2A7 Nck-associated protein 1 protein 20130415 {GO:0005515=IPI, GO:0001756=IEA, GO:0030032=IEA, GO:0048570=IEA, GO:0005829=TAS, GO:0032880=IEA, GO:0008078=IEA, GO:0010172=IEA, GO:0035050=IEA, GO:0030950=IEA, GO:0031258=IEA, GO:0007354=IEA, GO:0050821=IEA, GO:0001843=IEA, GO:0006915=TAS, GO:0045176=IEA, GO:0045175=IEA, GO:0007417=TAS, GO:0001701=IEA, GO:0007492=IEA, GO:0045087=TAS, GO:0048617=IEA, GO:0048340=IEA, GO:0016021=IEA, GO:0038096=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, apical protein localization, apoptotic process, basal protein localization, central nervous system development, embryonic body morphogenesis, embryonic foregut morphogenesis, embryonic heart tube development, endoderm development, establishment or maintenance of actin cytoskeleton polarity, in utero embryonic development, innate immune response, lamellipodium assembly, mesodermal cell migration, neural tube closure, notochord morphogenesis, paraxial mesoderm morphogenesis, protein stabilization, regulation of protein localization, somitogenesis, zygotic determination of anterior/posterior axis, embryo cytosol, integral to membrane, lamellipodium membrane protein binding Human UniProtKB:Q7L576 NCKAP1L GOC UniProtKB {GO:0050853=PMID:17875758, GO:0005515=PMID:16417406, GO:0031209=PMID:16417406, GO:0001782=GO_REF:0000024, GO:0032715=GO_REF:0000024, GO:0030890=PMID:17875758, GO:0045579=GO_REF:0000024, GO:0030011=PMID:16417406, GO:0043378=GO_REF:0000024, GO:0032855=PMID:16417406, GO:0032403=PMID:16417406, GO:0042221=PMID:16417406, GO:0060100=GO_REF:0000024, GO:0005829=PMID:16417406, GO:0070358=PMID:16417406, GO:0030838=PMID:16417406, GO:0048821=PMID:7643388, GO:0045860=PMID:16417406, GO:0042102=GO_REF:0000024, GO:0043029=GO_REF:0000024, GO:0002262=GO_REF:0000024, GO:0030675=PMID:16417406, GO:0035509=PMID:16417406, GO:0043066=PMID:17875758, GO:0042493=PMID:17875758, GO:0045588=GO_REF:0000024, GO:0030593=PMID:16417406, GO:0033630=GO_REF:0000024, GO:0030295=PMID:16417406, GO:0032700=GO_REF:0000024, GO:0006461=GO_REF:0000024, GO:0016020=PMID:1932118, GO:0030866=PMID:16417406, GO:0005887=PMID:1932118, GO:0045648=GO_REF:0000024, GO:0043372=GO_REF:0000024, GO:0090023=GO_REF:0000024, GO:0045621=GO_REF:0000024, GO:0042327=PMID:16417406} P55160 Nck-associated protein 1-like protein 20130413 {GO:0050853=IMP, GO:0005515=IPI, GO:0031209=IDA, GO:0001782=ISS, GO:0032715=ISS, GO:0030890=IMP, GO:0045579=ISS, GO:0030011=IMP, GO:0043378=ISS, GO:0032855=IMP, GO:0032403=IDA, GO:0042221=IDA, GO:0060100=ISS, GO:0005829=IDA, GO:0070358=IMP, GO:0030838=IMP, GO:0048821=IEP, GO:0045860=IMP, GO:0042102=ISS, GO:0043029=ISS, GO:0002262=ISS, GO:0030675=IMP, GO:0035509=IMP, GO:0043066=IMP, GO:0042493=IMP, GO:0045588=ISS, GO:0030593=IDA, GO:0033630=ISS, GO:0030295=IMP, GO:0032700=ISS, GO:0006461=ISS, GO:0016020=TAS, GO:0030866=IMP, GO:0005887=NAS, GO:0045648=ISS, GO:0043372=ISS, GO:0090023=ISS, GO:0045621=ISS, GO:0042327=IMP} B cell homeostasis, B cell receptor signaling pathway, T cell homeostasis, actin polymerization-dependent cell motility, cortical actin cytoskeleton organization, erythrocyte development, maintenance of cell polarity, myeloid cell homeostasis, negative regulation of apoptotic process, negative regulation of interleukin-17 production, negative regulation of interleukin-6 production, negative regulation of myosin-light-chain-phosphatase activity, neutrophil chemotaxis, positive regulation of B cell differentiation, positive regulation of B cell proliferation, positive regulation of CD4-positive, alpha-beta T cell differentiation, positive regulation of CD8-positive, alpha-beta T cell differentiation, positive regulation of Rac GTPase activity, positive regulation of T cell proliferation, positive regulation of actin filament polymerization, positive regulation of cell adhesion mediated by integrin, positive regulation of erythrocyte differentiation, positive regulation of gamma-delta T cell differentiation, positive regulation of lymphocyte differentiation, positive regulation of neutrophil chemotaxis, positive regulation of phagocytosis, engulfment, positive regulation of phosphorylation, positive regulation of protein kinase activity, protein complex assembly, response to chemical stimulus, response to drug SCAR complex, cytosol, integral to plasma membrane, membrane Rac GTPase activator activity, protein binding, protein complex binding, protein kinase activator activity Human NCKAP5 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} O14513 Nck-associated protein 5 protein 20061026 {GO:0008150=ND, GO:0005575=ND} biological_process cellular_component Human NCKAP5L null null {} null null null null {} null null null NCKIPSD BHF-UCL UniProtKB {GO:0005515=PMID:15095401, GO:0008092=PMID:10619843, GO:0005882=PMID:10619843, GO:0007165=PMID:10648423, GO:0017124=GO_REF:0000037, GO:0008180=PMID:18850735, GO:0045087=Reactome:REACT_6802, GO:0007010=PMID:10619843, GO:0038096=Reactome:REACT_160123, GO:0006607=PMID:10648423, GO:0005829=Reactome:REACT_160291} Q9NZQ3 NCK-interacting protein with SH3 domain protein 20110706 {GO:0005515=IPI, GO:0008092=NAS, GO:0005882=NAS, GO:0007165=TAS, GO:0017124=IEA, GO:0008180=IDA, GO:0045087=TAS, GO:0007010=NAS, GO:0038096=TAS, GO:0006607=TAS, GO:0005829=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, NLS-bearing substrate import into nucleus, cytoskeleton organization, innate immune response, signal transduction cytosol, intermediate filament, signalosome SH3 domain binding, cytoskeletal protein binding, protein binding Human UniProtKB:Q9Y613 NCL HPA UniProtKB {GO:0005515=PMID:19174163, GO:0000166=GO_REF:0000002, GO:0030529=PMID:18809582, GO:0003723=PMID:8321232, GO:0042162=PMID:8321232, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005654=GO_REF:0000019, GO:0001525=PMID:16403913, GO:0008022=PMID:16403913, GO:0003676=GO_REF:0000002, GO:0005938=PMID:16403913} P19338 Nucleolin protein 20100326 {GO:0005515=IPI, GO:0000166=IEA, GO:0030529=IDA, GO:0003723=IDA, GO:0042162=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0005654=IEA, GO:0001525=IDA, GO:0008022=IPI, GO:0003676=IEA, GO:0005938=IDA} angiogenesis cell cortex, nucleolus, nucleoplasm, nucleus, ribonucleoprotein complex RNA binding, nucleic acid binding, nucleotide binding, protein C-terminus binding, protein binding, telomeric DNA binding Human NCLN HPA UniProtKB {GO:0005515=PMID:17261586, GO:0005783=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005789=GO_REF:0000039, GO:0006508=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0008233=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0009966=GO_REF:0000002, GO:0043231=GO_REF:0000052} Q969V3 Nicalin protein 20110516 {GO:0005515=IPI, GO:0005783=IDA, GO:0005730=IDA, GO:0005789=IEA, GO:0006508=IEA, GO:0005634=IDA, GO:0008233=IEA, GO:0016021=IEA, GO:0009966=IEA, GO:0043231=IDA} proteolysis, regulation of signal transduction endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle, nucleolus, nucleus peptidase activity, protein binding Human NCOA1 BHF-UCL UniProtKB {GO:0005515=PMID:17363140, GO:0000790=PMID:17363140, GO:0035257=PMID:10207113, GO:0005634=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0050681=PMID:15572661, GO:0030374=PMID:17363140, GO:0045944=PMID:15919756, GO:0046983=GO_REF:0000002, GO:2001038=GO_REF:0000019, GO:0004871=GO_REF:0000002, GO:0044255=Reactome:REACT_22279, GO:0004402=GO_REF:0000003, GO:0000435=PMID:10207113, GO:0016922=PMID:17363140, GO:0006355=GO_REF:0000002, GO:0043065=GO_REF:0000019, GO:0003713=PMID:10207113, GO:0003677=GO_REF:0000019, GO:0006351=PMID:9223431, GO:0047485=PMID:12917342, GO:0045666=GO_REF:0000019, GO:0043967=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0005654=Reactome:REACT_19175, GO:0045893=PMID:11891224, GO:0019899=PMID:12039952, GO:0030521=PMID:15572661} Q15788 Nuclear receptor coactivator 1 protein 20110811 {GO:0005515=IPI, GO:0000790=IDA, GO:0035257=IDA, GO:0005634=IEA, GO:0044281=TAS, GO:0050681=NAS, GO:0030374=IDA, GO:0045944=IDA, GO:0046983=IEA, GO:2001038=IEA, GO:0004871=IEA, GO:0044255=TAS, GO:0004402=IEA, GO:0000435=IDA, GO:0016922=IPI, GO:0006355=IEA, GO:0043065=IEA, GO:0003713=IDA, GO:0003677=IEA, GO:0006351=IDA, GO:0047485=IPI, GO:0045666=IEA, GO:0043967=IEA, GO:0003682=IEA, GO:0005654=TAS, GO:0045893=IDA, GO:0019899=IPI, GO:0030521=NAS} androgen receptor signaling pathway, cellular lipid metabolic process, histone H4 acetylation, positive regulation of apoptotic process, positive regulation of neuron differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter by galactose, positive regulation of transcription, DNA-dependent, regulation of cellular response to drug, regulation of transcription, DNA-dependent, small molecule metabolic process, transcription, DNA-dependent nuclear chromatin, nucleoplasm, nucleus DNA binding, androgen receptor binding, chromatin binding, enzyme binding, histone acetyltransferase activity, ligand-dependent nuclear receptor binding, ligand-dependent nuclear receptor transcription coactivator activity, nuclear hormone receptor binding, protein N-terminus binding, protein binding, protein dimerization activity, signal transducer activity, transcription coactivator activity Human UniProtKB:P03372 NCOA2 BHF-UCL UniProtKB {GO:0005515=PMID:15563469, GO:0016922=PMID:18798693, GO:0006355=PMID:8670870, GO:0003713=PMID:9430642, GO:0035257=GO_REF:0000002, GO:0005634=GO_REF:0000029, GO:0044281=Reactome:REACT_111217, GO:0000122=GO_REF:0000019, GO:0003677=GO_REF:0000038, GO:0006351=GO_REF:0000037, GO:0030375=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0030374=PMID:17363140, GO:0045944=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0005654=Reactome:REACT_19175, GO:0004871=GO_REF:0000002, GO:0044255=Reactome:REACT_22279, GO:0030521=PMID:19641626, GO:0004402=GO_REF:0000002} Q15596 Nuclear receptor coactivator 2 protein 20110811 {GO:0005515=IPI, GO:0016922=IPI, GO:0006355=NAS, GO:0003713=NAS, GO:0035257=IEA, GO:0005634=NAS, GO:0044281=TAS, GO:0000122=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0030375=IEA, GO:0005737=IEA, GO:0030374=IDA, GO:0045944=IEA, GO:0003682=IEA, GO:0046983=IEA, GO:0005654=TAS, GO:0004871=IEA, GO:0044255=TAS, GO:0030521=RCA, GO:0004402=IEA} androgen receptor signaling pathway, cellular lipid metabolic process, negative regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, small molecule metabolic process, transcription, DNA-dependent cytoplasm, nucleoplasm, nucleus DNA binding, chromatin binding, histone acetyltransferase activity, ligand-dependent nuclear receptor binding, ligand-dependent nuclear receptor transcription coactivator activity, nuclear hormone receptor binding, protein binding, protein dimerization activity, signal transducer activity, thyroid hormone receptor coactivator activity, transcription coactivator activity Human NCOA3 HPA UniProtKB {GO:0005515=PMID:21577200, GO:0060068=GO_REF:0000019, GO:0035257=PMID:9267036, GO:0005634=GO_REF:0000052, GO:0050681=PMID:15572661, GO:0046966=PMID:9346901, GO:0005737=GO_REF:0000052, GO:0048589=GO_REF:0000019, GO:0045618=PMID:17082781, GO:0035264=GO_REF:0000019, GO:0045944=PMID:9267036, GO:0046983=GO_REF:0000002, GO:0004871=GO_REF:0000002, GO:2001141=PMID:17223341, GO:0004402=PMID:9267036, GO:0016922=PMID:18798693, GO:0006355=GO_REF:0000038, GO:0016573=PMID:9267036, GO:0060744=GO_REF:0000019, GO:0035624=PMID:17223341, GO:0003713=PMID:17223341, GO:0005730=GO_REF:0000052, GO:0006351=GO_REF:0000037, GO:0047485=PMID:12917342, GO:0003682=GO_REF:0000019, GO:0045893=PMID:15572661, GO:0030521=PMID:15572661} Q9Y6Q9 Nuclear receptor coactivator 3 protein 20111111 {GO:0005515=IPI, GO:0060068=IEA, GO:0035257=IDA, GO:0005634=IDA, GO:0050681=NAS, GO:0046966=NAS, GO:0005737=IDA, GO:0048589=IEA, GO:0045618=IMP, GO:0035264=IEA, GO:0045944=IDA, GO:0046983=IEA, GO:0004871=IEA, GO:2001141=IMP, GO:0004402=IDA, GO:0016922=IPI, GO:0006355=IEA, GO:0016573=IDA, GO:0060744=IEA, GO:0035624=TAS, GO:0003713=IMP, GO:0005730=IDA, GO:0006351=IEA, GO:0047485=IPI, GO:0003682=IEA, GO:0045893=NAS, GO:0030521=NAS} androgen receptor signaling pathway, developmental growth, histone acetylation, mammary gland branching involved in thelarche, multicellular organism growth, positive regulation of keratinocyte differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, receptor transactivation, regulation of RNA biosynthetic process, regulation of transcription, DNA-dependent, transcription, DNA-dependent, vagina development cytoplasm, nucleolus, nucleus androgen receptor binding, chromatin binding, histone acetyltransferase activity, ligand-dependent nuclear receptor binding, nuclear hormone receptor binding, protein N-terminus binding, protein binding, protein dimerization activity, signal transducer activity, thyroid hormone receptor binding, transcription coactivator activity Human NCOA4 PINC UniProtKB {GO:0003713=PMID:15572661, GO:0005634=PMID:8643607, GO:0050681=PMID:15572661, GO:0045893=PMID:15572661, GO:0008584=PMID:8643607, GO:0030521=PMID:15572661, GO:0006351=GO_REF:0000037} Q13772 Nuclear receptor coactivator 4 protein 20030904 {GO:0003713=NAS, GO:0005634=TAS, GO:0050681=NAS, GO:0045893=NAS, GO:0008584=TAS, GO:0030521=NAS, GO:0006351=IEA} androgen receptor signaling pathway, male gonad development, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus androgen receptor binding, transcription coactivator activity Human NCOA5 IntAct UniProtKB {GO:0005515=PMID:11113208, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q9HCD5 Nuclear receptor coactivator 5 protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0005634=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus protein binding Human UniProtKB:Q60674 NCOA6 HPA UniProtKB {GO:0005515=PMID:17178841, GO:0006367=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0043231=GO_REF:0000052, GO:0007507=GO_REF:0000024, GO:0046966=PMID:11443112, GO:0046965=PMID:11443112, GO:0030374=PMID:11443112, GO:0045944=PMID:11443112, GO:0060716=GO_REF:0000019, GO:0030099=PMID:11302752, GO:0009725=PMID:11443112, GO:0044255=Reactome:REACT_22279, GO:0005667=PMID:11443112, GO:0006352=PMID:10567404, GO:0030331=PMID:11443112, GO:0003713=PMID:11443112, GO:0005730=GO_REF:0000052, GO:0006310=PMID:11443112, GO:0006974=PMID:17500065, GO:0006260=PMID:11443112, GO:0035097=PMID:17500065, GO:0006281=PMID:11443112, GO:0007420=GO_REF:0000024, GO:0003682=GO_REF:0000024, GO:0042921=PMID:11443112, GO:0005654=Reactome:REACT_19175, GO:0045893=PMID:12519782, GO:0019899=PMID:12039952, GO:0030520=PMID:11443112} Q14686 Nuclear receptor coactivator 6 protein 20080818 {GO:0005515=IPI, GO:0006367=ISS, GO:0005634=IDA, GO:0044281=TAS, GO:0043231=IDA, GO:0007507=ISS, GO:0046966=IDA, GO:0046965=TAS, GO:0030374=IPI, GO:0045944=IDA, GO:0060716=IEA, GO:0030099=IDA, GO:0009725=TAS, GO:0044255=TAS, GO:0005667=TAS, GO:0006352=IDA, GO:0030331=TAS, GO:0003713=IDA, GO:0005730=IDA, GO:0006310=NAS, GO:0006974=IDA, GO:0006260=NAS, GO:0035097=IDA, GO:0006281=NAS, GO:0007420=ISS, GO:0003682=ISS, GO:0042921=NAS, GO:0005654=TAS, GO:0045893=TAS, GO:0019899=IPI, GO:0030520=NAS} DNA recombination, DNA repair, DNA replication, DNA-dependent transcription, initiation, brain development, cellular lipid metabolic process, glucocorticoid receptor signaling pathway, heart development, intracellular estrogen receptor signaling pathway, labyrinthine layer blood vessel development, myeloid cell differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, response to DNA damage stimulus, response to hormone stimulus, small molecule metabolic process, transcription initiation from RNA polymerase II promoter histone methyltransferase complex, intracellular membrane-bounded organelle, nucleolus, nucleoplasm, nucleus, transcription factor complex chromatin binding, enzyme binding, estrogen receptor binding, ligand-dependent nuclear receptor transcription coactivator activity, protein binding, retinoid X receptor binding, thyroid hormone receptor binding, transcription coactivator activity Human NCOA7 IntAct UniProtKB {GO:0005515=PMID:20562859, GO:0005622=GO_REF:0000054, GO:0030374=PMID:11971969, GO:0045944=PMID:11971969, GO:0016998=GO_REF:0000002, GO:0035257=PMID:11971969, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q8NI08 Nuclear receptor coactivator 7 protein 20130415 {GO:0005515=IPI, GO:0005622=IDA, GO:0030374=IDA, GO:0045944=IDA, GO:0016998=IEA, GO:0035257=IDA, GO:0005634=IEA, GO:0006351=IEA} cell wall macromolecule catabolic process, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent intracellular, nucleus ligand-dependent nuclear receptor transcription coactivator activity, nuclear hormone receptor binding, protein binding Human UniProtKB:Q9H0R8 NCOR1 BHF-UCL UniProtKB {GO:0005515=PMID:11486045, GO:0010467=Reactome:REACT_71, GO:0000790=PMID:17505061, GO:0006367=Reactome:REACT_12627, GO:0003700=GO_REF:0000019, GO:0044212=GO_REF:0000024, GO:0042826=PMID:11804585, GO:0006366=PMID:7566114, GO:0005634=PMID:18052923, GO:0044281=Reactome:REACT_111217, GO:0046966=GO_REF:0000019, GO:0021794=GO_REF:0000019, GO:0046965=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0060318=GO_REF:0000019, GO:0046329=PMID:11931768, GO:0007219=Reactome:REACT_118859, GO:0016580=PMID:11486045, GO:0072362=PMID:19955185, GO:0017053=PMID:11804585, GO:0040014=GO_REF:0000019, GO:0002361=GO_REF:0000019, GO:0007179=Reactome:REACT_6844, GO:0005876=PMID:18326024, GO:2000191=PMID:19955185, GO:0044255=Reactome:REACT_22279, GO:0072368=PMID:19955185, GO:0042632=GO_REF:0000019, GO:0001102=PMID:19955185, GO:0005667=GO_REF:0000019, GO:0035033=GO_REF:0000019, GO:0003714=PMID:18052923, GO:0014067=GO_REF:0000019, GO:0000122=PMID:19955185, GO:0003677=GO_REF:0000002, GO:0051225=PMID:18326024, GO:0006351=Reactome:REACT_121061, GO:0032922=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0000118=PMID:18326024, GO:0031065=GO_REF:0000019, GO:0044428=PMID:10049357, GO:0003682=GO_REF:0000002, GO:0005654=Reactome:REACT_160192, GO:0016568=GO_REF:0000037} O75376 Nuclear receptor corepressor 1 protein 20110615 {GO:0005515=IPI, GO:0010467=TAS, GO:0000790=IDA, GO:0006367=TAS, GO:0003700=IEA, GO:0044212=ISS, GO:0042826=IPI, GO:0006366=TAS, GO:0005634=IC, GO:0044281=TAS, GO:0046966=IEA, GO:0021794=IEA, GO:0046965=IEA, GO:0005737=IEA, GO:0060318=IEA, GO:0046329=IDA, GO:0007219=TAS, GO:0016580=IDA, GO:0072362=IMP, GO:0017053=IDA, GO:0040014=IEA, GO:0002361=IEA, GO:0007179=TAS, GO:0005876=IDA, GO:2000191=IC, GO:0044255=TAS, GO:0072368=IMP, GO:0042632=IEA, GO:0001102=IPI, GO:0005667=IEA, GO:0035033=IEA, GO:0003714=IDA, GO:0014067=IEA, GO:0000122=IMP, GO:0003677=IEA, GO:0051225=IMP, GO:0006351=TAS, GO:0032922=IEA, GO:0043565=IEA, GO:0000118=IDA, GO:0031065=IEA, GO:0044428=IDA, GO:0003682=IEA, GO:0005654=TAS, GO:0016568=IEA} CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation, Notch signaling pathway, cellular lipid metabolic process, cholesterol homeostasis, chromatin modification, circadian regulation of gene expression, definitive erythrocyte differentiation, gene expression, negative regulation of JNK cascade, negative regulation of phosphatidylinositol 3-kinase cascade, negative regulation of transcription from RNA polymerase II promoter, positive regulation of histone deacetylation, regulation of fatty acid transport, regulation of glycolysis by negative regulation of transcription from RNA polymerase II promoter, regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter, regulation of multicellular organism growth, small molecule metabolic process, spindle assembly, thalamus development, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway Sin3 complex, cytoplasm, histone deacetylase complex, nuclear chromatin, nuclear part, nucleoplasm, nucleus, spindle microtubule, transcription factor complex, transcriptional repressor complex DNA binding, RNA polymerase II activating transcription factor binding, chromatin binding, histone deacetylase binding, histone deacetylase regulator activity, protein binding, retinoid X receptor binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, thyroid hormone receptor binding, transcription corepressor activity, transcription regulatory region DNA binding colocalizes_with Human NCOR2 HPA UniProtKB {GO:0005515=PMID:20195357, GO:0010467=Reactome:REACT_71, GO:0021846=GO_REF:0000019, GO:0006367=Reactome:REACT_12627, GO:0042826=PMID:11804585, GO:0045599=GO_REF:0000019, GO:0005112=PMID:10713164, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0060206=GO_REF:0000019, GO:0035259=GO_REF:0000019, GO:0021537=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0046965=GO_REF:0000019, GO:0072365=PMID:19955185, GO:0007219=Reactome:REACT_118859, GO:0017053=PMID:11804585, GO:0007179=Reactome:REACT_6844, GO:0000785=GO_REF:0000019, GO:0032355=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0016922=GO_REF:0000019, GO:0003714=PMID:18052923, GO:0005730=GO_REF:0000052, GO:0010243=GO_REF:0000019, GO:0000122=PMID:19955185, GO:0042593=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0006351=Reactome:REACT_121061, GO:0043565=GO_REF:0000019, GO:0016604=PMID:16030140, GO:0003007=GO_REF:0000019, GO:0047485=PMID:16893456, GO:0000118=GO_REF:0000019, GO:0007595=GO_REF:0000019, GO:0050872=GO_REF:0000019, GO:0003682=GO_REF:0000002, GO:0005654=Reactome:REACT_160192, GO:0001012=GO_REF:0000019} Q9Y618 Nuclear receptor corepressor 2 protein 20080818 {GO:0005515=IPI, GO:0010467=TAS, GO:0021846=IEA, GO:0006367=TAS, GO:0042826=IPI, GO:0045599=IEA, GO:0005112=IPI, GO:0005634=IDA, GO:0044281=TAS, GO:0060206=IEA, GO:0035259=IEA, GO:0021537=IEA, GO:0032403=IEA, GO:0046965=IEA, GO:0072365=IMP, GO:0007219=TAS, GO:0017053=IDA, GO:0007179=TAS, GO:0000785=IEA, GO:0032355=IEA, GO:0044255=TAS, GO:0016922=IEA, GO:0003714=IDA, GO:0005730=IDA, GO:0010243=IEA, GO:0000122=IMP, GO:0042593=IEA, GO:0001701=IEA, GO:0003677=IEA, GO:0006351=TAS, GO:0043565=IEA, GO:0016604=IDA, GO:0003007=IEA, GO:0047485=IPI, GO:0000118=IEA, GO:0007595=IEA, GO:0050872=IEA, GO:0003682=IEA, GO:0005654=TAS, GO:0001012=IEA} Notch signaling pathway, cell proliferation in forebrain, cellular lipid metabolic process, estrous cycle phase, gene expression, glucose homeostasis, heart morphogenesis, in utero embryonic development, lactation, negative regulation of fat cell differentiation, negative regulation of transcription from RNA polymerase II promoter, regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter, response to estradiol stimulus, response to organic nitrogen, small molecule metabolic process, telencephalon development, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, white fat cell differentiation chromatin, histone deacetylase complex, nuclear body, nucleolus, nucleoplasm, nucleus, transcriptional repressor complex DNA binding, Notch binding, RNA polymerase II regulatory region DNA binding, chromatin binding, glucocorticoid receptor binding, histone deacetylase binding, ligand-dependent nuclear receptor binding, protein N-terminus binding, protein binding, protein complex binding, retinoid X receptor binding, sequence-specific DNA binding, transcription corepressor activity NOT Human NCR1 PINC UniProtKB {GO:0042269=PMID:15654827, GO:0007165=PMID:9730896, GO:0006968=PMID:9730896, GO:0030101=PMID:9730896, GO:0016514=GO_REF:0000024, GO:0005887=PMID:9730896, GO:0005057=PMID:9730896} O76036 Natural cytotoxicity triggering receptor 1 protein 20030904 {GO:0042269=TAS, GO:0007165=TAS, GO:0006968=TAS, GO:0030101=NAS, GO:0016514=ISS, GO:0005887=NAS, GO:0005057=TAS} cellular defense response, natural killer cell activation, regulation of natural killer cell mediated cytotoxicity, signal transduction SWI/SNF complex, integral to plasma membrane receptor signaling protein activity Human NCR2 Reactome UniProtKB {GO:0007165=PMID:10049942, GO:0006968=PMID:10049942, GO:0005886=Reactome:REACT_147726, GO:0005887=PMID:10049942, GO:0045087=Reactome:REACT_6802, GO:0004888=PMID:10049942} O95944 Natural cytotoxicity triggering receptor 2 protein 20120619 {GO:0007165=TAS, GO:0006968=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0045087=TAS, GO:0004888=TAS} cellular defense response, innate immune response, signal transduction integral to plasma membrane, plasma membrane transmembrane signaling receptor activity Human NCR3 BHF-UCL UniProtKB {GO:0008037=PMID:16304049, GO:0006955=PMID:10941844, GO:0006954=PMID:10941844, GO:0005887=PMID:7590964, GO:0045954=PMID:16304049} O14931 Natural cytotoxicity triggering receptor 3 protein 20081127 {GO:0008037=TAS, GO:0006955=NAS, GO:0006954=NAS, GO:0005887=TAS, GO:0045954=IMP} cell recognition, immune response, inflammatory response, positive regulation of natural killer cell mediated cytotoxicity integral to plasma membrane Human NCS1 HPA UniProtKB {GO:0005515=PMID:12783849, GO:0030424=GO_REF:0000019, GO:0048471=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0005245=GO_REF:0000024, GO:0005886=GO_REF:0000052, GO:0048015=GO_REF:0000019, GO:0005509=PMID:11092894, GO:0014069=GO_REF:0000039, GO:0031410=GO_REF:0000019, GO:0043231=GO_REF:0000052, GO:0005829=GO_REF:0000019, GO:0045921=GO_REF:0000019, GO:0005737=PMID:12783849, GO:0010975=GO_REF:0000024, GO:0045211=GO_REF:0000037, GO:0032580=GO_REF:0000039} P62166 Neuronal calcium sensor 1 protein 20101115 {GO:0005515=IPI, GO:0030424=IEA, GO:0048471=IEA, GO:0030054=IEA, GO:0005245=ISS, GO:0005886=IDA, GO:0048015=IEA, GO:0005509=TAS, GO:0014069=IEA, GO:0031410=IEA, GO:0043231=IDA, GO:0005829=IEA, GO:0045921=IEA, GO:0005737=IDA, GO:0010975=ISS, GO:0045211=IEA, GO:0032580=IEA} phosphatidylinositol-mediated signaling, positive regulation of exocytosis, regulation of neuron projection development Golgi cisterna membrane, axon, cell junction, cytoplasm, cytoplasmic vesicle, cytosol, intracellular membrane-bounded organelle, perinuclear region of cytoplasm, plasma membrane, postsynaptic density, postsynaptic membrane calcium ion binding, protein binding, voltage-gated calcium channel activity Human NCSTN IntAct UniProtKB {GO:0042987=PMID:15274632, GO:0005515=PMID:16641999, GO:0042470=GO_REF:0000039, GO:0048011=Reactome:REACT_13776, GO:0007220=Reactome:REACT_691, GO:0005794=PMID:15274632, GO:0005886=Reactome:REACT_160171, GO:0031293=Reactome:REACT_13443, GO:0005783=PMID:15274632, GO:0006915=Reactome:REACT_13643, GO:0043085=PMID:15274632, GO:0005765=GO_REF:0000019, GO:0097190=Reactome:REACT_13720, GO:0050435=GO_REF:0000019, GO:0050673=GO_REF:0000019, GO:0007219=Reactome:REACT_118862, GO:0004175=GO_REF:0000019, GO:0042098=GO_REF:0000019, GO:0005887=PMID:15274632, GO:0016485=PMID:15274632, GO:0006508=PMID:10993067, GO:0006509=PMID:15274632, GO:0016021=PMID:10993067, GO:0002262=GO_REF:0000019} Q92542 Nicastrin protein 20130415 {GO:0042987=TAS, GO:0005515=IPI, GO:0042470=IEA, GO:0048011=TAS, GO:0007220=TAS, GO:0005794=IDA, GO:0005886=TAS, GO:0031293=TAS, GO:0005783=IDA, GO:0006915=TAS, GO:0043085=IDA, GO:0005765=IEA, GO:0097190=TAS, GO:0050435=IEA, GO:0050673=IEA, GO:0007219=TAS, GO:0004175=IEA, GO:0042098=IEA, GO:0005887=IDA, GO:0016485=IDA, GO:0006508=NAS, GO:0006509=IDA, GO:0016021=NAS, GO:0002262=IEA} Notch receptor processing, Notch signaling pathway, T cell proliferation, amyloid precursor protein catabolic process, apoptotic process, apoptotic signaling pathway, beta-amyloid metabolic process, epithelial cell proliferation, membrane protein ectodomain proteolysis, membrane protein intracellular domain proteolysis, myeloid cell homeostasis, neurotrophin TRK receptor signaling pathway, positive regulation of catalytic activity, protein processing, proteolysis Golgi apparatus, endoplasmic reticulum, integral to membrane, integral to plasma membrane, lysosomal membrane, melanosome, plasma membrane endopeptidase activity, protein binding Human UniProtKB:P49755 NDC80 BHF-UCL UniProtKB {GO:0005515=PMID:20360068, GO:0000236=Reactome:REACT_682, GO:0048015=PMID:15504738, GO:0000132=PMID:19468067, GO:0005634=PMID:9315664, GO:0005829=Reactome:REACT_150414, GO:0007067=PMID:9315664, GO:0007049=PMID:15504738, GO:0000070=PMID:9315664, GO:0007059=PMID:14699129, GO:0000942=PMID:18195732, GO:0000087=Reactome:REACT_910, GO:0000777=PMID:14699129, GO:0000776=PMID:19468067, GO:0007051=PMID:15504738, GO:0000278=Reactome:REACT_152, GO:0007052=PMID:14699129, GO:0008608=PMID:19468067, GO:0000090=Reactome:REACT_1275, GO:0000775=PMID:9315664, GO:0031262=PMID:14699129, GO:0051301=GO_REF:0000037} O14777 Kinetochore protein NDC80 homolog protein 20100107 {GO:0005515=IPI, GO:0000236=TAS, GO:0048015=NAS, GO:0000132=IMP, GO:0005634=TAS, GO:0005829=TAS, GO:0007067=TAS, GO:0007049=NAS, GO:0000070=TAS, GO:0007059=IMP, GO:0000942=IDA, GO:0000087=TAS, GO:0000777=IDA, GO:0000776=IDA, GO:0007051=NAS, GO:0000278=TAS, GO:0007052=IMP, GO:0008608=IMP, GO:0000090=TAS, GO:0000775=TAS, GO:0031262=IDA, GO:0051301=IEA} M phase of mitotic cell cycle, attachment of spindle microtubules to kinetochore, cell cycle, cell division, chromosome segregation, establishment of mitotic spindle orientation, mitosis, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, mitotic sister chromatid segregation, mitotic spindle organization, phosphatidylinositol-mediated signaling, spindle organization Ndc80 complex, chromosome, centromeric region, condensed chromosome kinetochore, condensed nuclear chromosome outer kinetochore, cytosol, kinetochore, nucleus protein binding Human NDE1 Reactome UniProtKB {GO:0008017=GO_REF:0000024, GO:0005515=PMID:17600710, GO:0000236=Reactome:REACT_682, GO:0021987=PMID:21529752, GO:0000132=PMID:19468067, GO:0032154=GO_REF:0000039, GO:0042802=GO_REF:0000019, GO:0007405=GO_REF:0000019, GO:0005829=Reactome:REACT_150414, GO:0047496=GO_REF:0000019, GO:0000086=Reactome:REACT_2203, GO:0000087=Reactome:REACT_910, GO:0005813=PMID:21399614, GO:0005874=GO_REF:0000037, GO:0019904=GO_REF:0000019, GO:0051298=GO_REF:0000024, GO:0051303=PMID:17600710, GO:0007020=GO_REF:0000019, GO:0000777=GO_REF:0000039, GO:0000776=PMID:17600710, GO:0031616=GO_REF:0000024, GO:0001764=GO_REF:0000019, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q9NXR1 Nuclear distribution protein nudE homolog 1 protein 20130213 {GO:0008017=ISS, GO:0005515=IPI, GO:0000236=TAS, GO:0021987=IMP, GO:0000132=IMP, GO:0032154=IEA, GO:0042802=IEA, GO:0007405=IEA, GO:0005829=TAS, GO:0047496=IEA, GO:0000086=TAS, GO:0000087=TAS, GO:0005813=IDA, GO:0005874=IEA, GO:0019904=IEA, GO:0051298=ISS, GO:0051303=IMP, GO:0007020=IEA, GO:0000777=IEA, GO:0000776=IDA, GO:0031616=ISS, GO:0001764=IEA, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, cell division, centrosome duplication, cerebral cortex development, establishment of chromosome localization, establishment of mitotic spindle orientation, microtubule nucleation, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, neuroblast proliferation, neuron migration, vesicle transport along microtubule centrosome, cleavage furrow, condensed chromosome kinetochore, cytosol, kinetochore, microtubule, spindle pole centrosome identical protein binding, microtubule binding, protein binding, protein domain specific binding Human NDEL1 IntAct UniProtKB {GO:0005515=PMID:17043677, GO:0008017=GO_REF:0000019, GO:0000236=Reactome:REACT_682, GO:0030424=GO_REF:0000019, GO:0008090=GO_REF:0000019, GO:0001833=GO_REF:0000019, GO:0045773=GO_REF:0000019, GO:0005635=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0005829=Reactome:REACT_150414, GO:0005737=GO_REF:0000019, GO:0051642=GO_REF:0000019, GO:0007059=PMID:17600710, GO:0047496=GO_REF:0000019, GO:0048680=GO_REF:0000019, GO:0000087=Reactome:REACT_910, GO:0021799=GO_REF:0000019, GO:0031252=GO_REF:0000019, GO:0060053=GO_REF:0000019, GO:0005871=GO_REF:0000019, GO:0005813=GO_REF:0000019, GO:0060052=GO_REF:0000019, GO:0043014=GO_REF:0000019, GO:0005874=GO_REF:0000037, GO:0021955=GO_REF:0000019, GO:0005819=GO_REF:0000039, GO:0048487=GO_REF:0000019, GO:0000226=GO_REF:0000019, GO:0032864=GO_REF:0000019, GO:0044297=GO_REF:0000019, GO:0070012=GO_REF:0000019, GO:0000777=GO_REF:0000039, GO:0000776=PMID:17600710, GO:0000278=Reactome:REACT_152, GO:0001764=GO_REF:0000019, GO:0051081=GO_REF:0000019, GO:0000090=Reactome:REACT_1275} Q9GZM8 Nuclear distribution protein nudE-like 1 protein 20130415 {GO:0005515=IPI, GO:0008017=IEA, GO:0000236=TAS, GO:0030424=IEA, GO:0008090=IEA, GO:0001833=IEA, GO:0045773=IEA, GO:0005635=IEA, GO:0032403=IEA, GO:0005829=TAS, GO:0005737=IEA, GO:0051642=IEA, GO:0007059=IMP, GO:0047496=IEA, GO:0048680=IEA, GO:0000087=TAS, GO:0021799=IEA, GO:0031252=IEA, GO:0060053=IEA, GO:0005871=IEA, GO:0005813=IEA, GO:0060052=IEA, GO:0043014=IEA, GO:0005874=IEA, GO:0021955=IEA, GO:0005819=IEA, GO:0048487=IEA, GO:0000226=IEA, GO:0032864=IEA, GO:0044297=IEA, GO:0070012=IEA, GO:0000777=IEA, GO:0000776=IDA, GO:0000278=TAS, GO:0001764=IEA, GO:0051081=IEA, GO:0000090=TAS} M phase of mitotic cell cycle, activation of Cdc42 GTPase activity, central nervous system neuron axonogenesis, centrosome localization, cerebral cortex radially oriented cell migration, chromosome segregation, inner cell mass cell proliferation, microtubule cytoskeleton organization, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, neurofilament cytoskeleton organization, neuron migration, nuclear envelope disassembly, positive regulation of axon extension, positive regulation of axon regeneration, retrograde axon cargo transport, vesicle transport along microtubule axon, cell body, cell leading edge, centrosome, condensed chromosome kinetochore, cytoplasm, cytosol, kinesin complex, kinetochore, microtubule, neurofilament cytoskeleton, nuclear envelope, spindle alpha-tubulin binding, beta-tubulin binding, microtubule binding, oligopeptidase activity, protein binding, protein complex binding Human UniProtKB:Q9NRI5 NDFIP1 GOC UniProtKB {GO:0048302=GO_REF:0000019, GO:0005515=PMID:18776082, GO:0045732=GO_REF:0000019, GO:0048471=PMID:18776082, GO:0032713=GO_REF:0000019, GO:0032410=PMID:18776082, GO:0002761=GO_REF:0000019, GO:0048294=GO_REF:0000019, GO:0042130=GO_REF:0000019, GO:0006879=PMID:18776082, GO:0045619=GO_REF:0000019, GO:0002829=GO_REF:0000019, GO:0031398=PMID:18776082, GO:0004871=PMID:12761501, GO:0043123=PMID:12761501, GO:0005938=GO_REF:0000019, GO:0050699=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0051224=PMID:18776082, GO:0007165=PMID:12761501, GO:0000139=GO_REF:0000039, GO:0050728=GO_REF:0000019, GO:0010629=PMID:18776082, GO:0016021=GO_REF:0000037, GO:0043162=GO_REF:0000019, GO:0010008=GO_REF:0000039} Q9BT67 NEDD4 family-interacting protein 1 protein 20130413 {GO:0048302=IEA, GO:0005515=IPI, GO:0045732=IEA, GO:0048471=IDA, GO:0032713=IEA, GO:0032410=IMP, GO:0002761=IEA, GO:0048294=IEA, GO:0042130=IEA, GO:0006879=IMP, GO:0045619=IEA, GO:0002829=IEA, GO:0031398=IMP, GO:0004871=IMP, GO:0043123=IMP, GO:0005938=IEA, GO:0050699=IEA, GO:0005576=IEA, GO:0051224=IMP, GO:0007165=IMP, GO:0000139=IEA, GO:0050728=IEA, GO:0010629=IMP, GO:0016021=IEA, GO:0043162=IEA, GO:0010008=IEA} cellular iron ion homeostasis, negative regulation of T cell proliferation, negative regulation of gene expression, negative regulation of inflammatory response, negative regulation of interleukin-4 production, negative regulation of isotype switching to IgE isotypes, negative regulation of protein transport, negative regulation of transporter activity, negative regulation of type 2 immune response, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of protein catabolic process, positive regulation of protein ubiquitination, regulation of isotype switching to IgG isotypes, regulation of lymphocyte differentiation, regulation of myeloid leukocyte differentiation, signal transduction, ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway Golgi membrane, cell cortex, endosome membrane, extracellular region, integral to membrane, perinuclear region of cytoplasm WW domain binding, protein binding, signal transducer activity Human NDFIP2 GOC UniProtKB {GO:0005515=PMID:18776082, GO:0048471=PMID:18776082, GO:0005794=PMID:12796489, GO:0005783=PMID:12796489, GO:0050699=PMID:12796489, GO:0032585=GO_REF:0000039, GO:0032410=PMID:18776082, GO:0051224=PMID:18776082, GO:0005739=PMID:12796489, GO:0007165=PMID:12761501, GO:0005737=PMID:12796489, GO:0000139=GO_REF:0000039, GO:0010629=PMID:18776082, GO:0031398=PMID:18776082, GO:0016021=GO_REF:0000037, GO:0004871=PMID:12761501, GO:0043123=PMID:12761501} Q9NV92 NEDD4 family-interacting protein 2 protein 20130413 {GO:0005515=IPI, GO:0048471=IDA, GO:0005794=IDA, GO:0005783=IDA, GO:0050699=IPI, GO:0032585=IEA, GO:0032410=IMP, GO:0051224=IMP, GO:0005739=IDA, GO:0007165=IMP, GO:0005737=IDA, GO:0000139=IEA, GO:0010629=IMP, GO:0031398=IMP, GO:0016021=IEA, GO:0004871=IMP, GO:0043123=IMP} negative regulation of gene expression, negative regulation of protein transport, negative regulation of transporter activity, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of protein ubiquitination, signal transduction Golgi apparatus, Golgi membrane, cytoplasm, endoplasmic reticulum, integral to membrane, mitochondrion, multivesicular body membrane, perinuclear region of cytoplasm WW domain binding, protein binding, signal transducer activity Human NDN PINC UniProtKB {GO:0048011=GO_REF:0000019, GO:0005813=GO_REF:0000019, GO:0006355=GO_REF:0000019, GO:0008285=PMID:9630521, GO:0043015=GO_REF:0000019, GO:0008347=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0042995=GO_REF:0000019, GO:0007417=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0019233=GO_REF:0000019, GO:0007399=PMID:9630521, GO:0005829=GO_REF:0000019, GO:0048871=GO_REF:0000019, GO:0003016=GO_REF:0000019, GO:0007413=GO_REF:0000019, GO:0071514=GO_REF:0000019, GO:0043204=GO_REF:0000039, GO:0001764=GO_REF:0000019, GO:0040008=GO_REF:0000037} Q99608 Necdin protein 20030904 {GO:0048011=IEA, GO:0005813=IEA, GO:0006355=IEA, GO:0008285=TAS, GO:0043015=IEA, GO:0008347=IEA, GO:0005634=IEA, GO:0042995=IEA, GO:0007417=IEA, GO:0009791=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0019233=IEA, GO:0007399=TAS, GO:0005829=IEA, GO:0048871=IEA, GO:0003016=IEA, GO:0007413=IEA, GO:0071514=IEA, GO:0043204=IEA, GO:0001764=IEA, GO:0040008=IEA} axonal fasciculation, central nervous system development, genetic imprinting, glial cell migration, multicellular organismal homeostasis, negative regulation of cell proliferation, nervous system development, neuron migration, neurotrophin TRK receptor signaling pathway, post-embryonic development, regulation of growth, regulation of transcription, DNA-dependent, respiratory system process, sensory perception of pain, transcription, DNA-dependent cell projection, centrosome, cytosol, nucleus, perikaryon DNA binding, gamma-tubulin binding Human NDNL2 IntAct UniProtKB {GO:0005515=PMID:21364888, GO:0005737=GO_REF:0000039, GO:0000781=GO_REF:0000039, GO:0006355=GO_REF:0000019, GO:0006281=GO_REF:0000037, GO:0030915=PMID:18086888, GO:0031398=PMID:20864041, GO:0005634=GO_REF:0000039, GO:0006310=GO_REF:0000037, GO:0040008=GO_REF:0000037} Q96MG7 Melanoma-associated antigen G1 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0000781=IEA, GO:0006355=IEA, GO:0006281=IEA, GO:0030915=IDA, GO:0031398=IDA, GO:0005634=IEA, GO:0006310=IEA, GO:0040008=IEA} DNA recombination, DNA repair, positive regulation of protein ubiquitination, regulation of growth, regulation of transcription, DNA-dependent Smc5-Smc6 complex, chromosome, telomeric region, cytoplasm, nucleus protein binding Human UniProtKB:Q8N140 NDOR1 HPA UniProtKB {GO:0036245=PMID:16140270, GO:0050661=PMID:10625700, GO:0005515=PMID:16140270, GO:0008219=PMID:16140270, GO:0048471=GO_REF:0000039, GO:0005506=GO_REF:0000002, GO:0010181=PMID:10625700, GO:0050660=PMID:10625700, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0005829=PMID:16140270, GO:0005737=GO_REF:0000052, GO:0003958=GO_REF:0000033, GO:0016709=GO_REF:0000033, GO:0016491=PMID:15900210, GO:0045111=GO_REF:0000052, GO:0055114=PMID:15900210} Q9UHB4 NADPH-dependent diflavin oxidoreductase 1 protein 20101115 {GO:0036245=IDA, GO:0050661=IDA, GO:0005515=IPI, GO:0008219=IDA, GO:0048471=IEA, GO:0005506=IEA, GO:0010181=IDA, GO:0050660=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0005829=IDA, GO:0005737=IDA, GO:0003958=IBA, GO:0016709=IBA, GO:0016491=IDA, GO:0045111=IDA, GO:0055114=IDA} cell death, cellular response to menadione, oxidation-reduction process, small molecule metabolic process cytoplasm, cytosol, intermediate filament cytoskeleton, nucleus, perinuclear region of cytoplasm FMN binding, NADP binding, NADPH-hemoprotein reductase activity, flavin adenine dinucleotide binding, iron ion binding, oxidoreductase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen, protein binding Human NDP BHF-UCL UniProtKB {GO:0043498=PMID:17955262, GO:0008283=PMID:8298646, GO:0007605=PMID:8298646, GO:0007267=PMID:8298646, GO:0061299=GO_REF:0000019, GO:0001890=GO_REF:0000019, GO:0035426=GO_REF:0000019, GO:0005615=PMID:17955262, GO:0005125=GO_REF:0000019, GO:0042803=PMID:17955262, GO:0007399=PMID:8252044, GO:0005109=PMID:17955262, GO:0031012=PMID:15035989, GO:0007165=PMID:8298646, GO:0051091=GO_REF:0000019, GO:0007033=PMID:10484772, GO:0016055=PMID:17955262, GO:0045893=PMID:17955262, GO:0007601=GO_REF:0000037, GO:0008083=PMID:8298646, GO:0060070=PMID:15035989} Q00604 Norrin protein 20100809 {GO:0043498=IDA, GO:0008283=TAS, GO:0007605=NAS, GO:0007267=TAS, GO:0061299=IEA, GO:0001890=IEA, GO:0035426=IEA, GO:0005615=IDA, GO:0005125=IEA, GO:0042803=IPI, GO:0007399=TAS, GO:0005109=IPI, GO:0031012=IDA, GO:0007165=TAS, GO:0051091=IEA, GO:0007033=TAS, GO:0016055=IDA, GO:0045893=IDA, GO:0007601=IEA, GO:0008083=TAS, GO:0060070=IDA} Wnt receptor signaling pathway, canonical Wnt receptor signaling pathway, cell proliferation, cell-cell signaling, extracellular matrix-cell signaling, nervous system development, placenta development, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription, DNA-dependent, retina vasculature morphogenesis in camera-type eye, sensory perception of sound, signal transduction, vacuole organization, visual perception extracellular matrix, extracellular space cell surface binding, cytokine activity, frizzled binding, growth factor activity, protein homodimerization activity Human UniProtKB:Q00604 NDRG1 HPA UniProtKB {GO:0005515=PMID:17220478, GO:0008017=PMID:15247272, GO:0045576=GO_REF:0000019, GO:0048471=PMID:17786215, GO:0017137=PMID:17786215, GO:0005813=PMID:15247272, GO:0045296=PMID:17786215, GO:0005886=PMID:12432451, GO:0043015=PMID:15247272, GO:0030330=PMID:9766676, GO:0005874=PMID:15247272, GO:0071456=PMID:20810912, GO:0005634=PMID:9766676, GO:0032287=GO_REF:0000019, GO:0090232=PMID:15247272, GO:0005829=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0005913=PMID:12432451, GO:0010038=PMID:9605764, GO:0015630=GO_REF:0000052, GO:0055038=PMID:17786215} Q92597 Protein NDRG1 protein 20101115 {GO:0005515=IPI, GO:0008017=IDA, GO:0045576=IEA, GO:0048471=IDA, GO:0017137=IDA, GO:0005813=IDA, GO:0045296=IDA, GO:0005886=IDA, GO:0043015=IDA, GO:0030330=IEP, GO:0005874=IDA, GO:0071456=IEP, GO:0005634=IDA, GO:0032287=IEA, GO:0090232=IDA, GO:0005829=IEA, GO:0005737=IDA, GO:0005913=IDA, GO:0010038=TAS, GO:0015630=IDA, GO:0055038=IDA} DNA damage response, signal transduction by p53 class mediator, cellular response to hypoxia, mast cell activation, peripheral nervous system myelin maintenance, positive regulation of spindle checkpoint, response to metal ion cell-cell adherens junction, centrosome, cytoplasm, cytosol, microtubule, microtubule cytoskeleton, nucleus, perinuclear region of cytoplasm, plasma membrane, recycling endosome membrane Rab GTPase binding, cadherin binding, gamma-tubulin binding, microtubule binding, protein binding Human NDRG2 HPA UniProtKB {GO:0005515=PMID:21217774, GO:0048471=GO_REF:0000039, GO:0005813=GO_REF:0000052, GO:0005794=GO_REF:0000054, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0001818=GO_REF:0000019, GO:0048662=GO_REF:0000019, GO:0010574=GO_REF:0000019, GO:0030154=GO_REF:0000037, GO:0005829=PMID:11936845, GO:0030426=GO_REF:0000039, GO:0007399=GO_REF:0000037, GO:0003674=GO_REF:0000015, GO:0007165=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0090361=GO_REF:0000019, GO:0070373=GO_REF:0000019, GO:0016055=GO_REF:0000037} Q9UN36 Protein NDRG2 protein 20100326 {GO:0005515=IPI, GO:0048471=IEA, GO:0005813=IDA, GO:0005794=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0001818=IEA, GO:0048662=IEA, GO:0010574=IEA, GO:0030154=IEA, GO:0005829=NAS, GO:0030426=IEA, GO:0007399=IEA, GO:0003674=ND, GO:0007165=IEA, GO:0005737=IDA, GO:0090361=IEA, GO:0070373=IEA, GO:0016055=IEA} Wnt receptor signaling pathway, cell differentiation, negative regulation of ERK1 and ERK2 cascade, negative regulation of cytokine production, negative regulation of smooth muscle cell proliferation, nervous system development, regulation of platelet-derived growth factor production, regulation of vascular endothelial growth factor production, signal transduction Golgi apparatus, centrosome, cytoplasm, cytosol, growth cone, nucleolus, nucleus, perinuclear region of cytoplasm molecular_function, protein binding Human NDRG3 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0005737=PMID:11936845, GO:0030308=PMID:11406283, GO:0007283=PMID:11406283, GO:0030154=PMID:11406283} Q9UGV2 Protein NDRG3 protein 20020808 {GO:0003674=ND, GO:0005737=IDA, GO:0030308=NAS, GO:0007283=NAS, GO:0030154=NAS} cell differentiation, negative regulation of cell growth, spermatogenesis cytoplasm molecular_function Human NDST1 Reactome UniProtKB {GO:0007585=GO_REF:0000019, GO:0005975=Reactome:REACT_474, GO:0019213=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0015012=GO_REF:0000041, GO:0048703=GO_REF:0000019, GO:0048702=GO_REF:0000019, GO:0006024=Reactome:REACT_121248, GO:0007224=GO_REF:0000019, GO:0015016=GO_REF:0000003, GO:0006954=GO_REF:0000037, GO:0000139=Reactome:REACT_121110, GO:0016787=GO_REF:0000002, GO:0000165=GO_REF:0000019, GO:0008543=GO_REF:0000019, GO:0008146=GO_REF:0000019, GO:0030901=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0030900=GO_REF:0000019, GO:0030203=Reactome:REACT_121315, GO:0030210=GO_REF:0000041, GO:0000271=GO_REF:0000019} P52848 Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 protein 20130301 {GO:0007585=IEA, GO:0005975=TAS, GO:0019213=IEA, GO:0044281=TAS, GO:0015012=IEA, GO:0048703=IEA, GO:0048702=IEA, GO:0006024=TAS, GO:0007224=IEA, GO:0015016=IEA, GO:0006954=IEA, GO:0000139=TAS, GO:0016787=IEA, GO:0000165=IEA, GO:0008543=IEA, GO:0008146=IEA, GO:0030901=IEA, GO:0016021=IEA, GO:0030900=IEA, GO:0030203=TAS, GO:0030210=IEA, GO:0000271=IEA} MAPK cascade, carbohydrate metabolic process, embryonic neurocranium morphogenesis, embryonic viscerocranium morphogenesis, fibroblast growth factor receptor signaling pathway, forebrain development, glycosaminoglycan biosynthetic process, glycosaminoglycan metabolic process, heparan sulfate proteoglycan biosynthetic process, heparin biosynthetic process, inflammatory response, midbrain development, polysaccharide biosynthetic process, respiratory gaseous exchange, small molecule metabolic process, smoothened signaling pathway Golgi membrane, integral to membrane "heparan sulfate""-glucosamine N-sulfotransferase activity, deacetylase activity, hydrolase activity, sulfotransferase activity""" Human NDST2 Reactome UniProtKB {GO:0005794=GO_REF:0000019, GO:0002002=GO_REF:0000019, GO:0009987=GO_REF:0000019, GO:0005975=Reactome:REACT_474, GO:0019213=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0015012=GO_REF:0000041, GO:0006024=Reactome:REACT_121248, GO:0015016=GO_REF:0000003, GO:0000139=Reactome:REACT_121110, GO:0008146=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0030203=Reactome:REACT_121315, GO:0030210=GO_REF:0000041} P52849 Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 protein 20130301 {GO:0005794=IEA, GO:0002002=IEA, GO:0009987=IEA, GO:0005975=TAS, GO:0019213=IEA, GO:0044281=TAS, GO:0015012=IEA, GO:0006024=TAS, GO:0015016=IEA, GO:0000139=TAS, GO:0008146=IEA, GO:0016021=IEA, GO:0030203=TAS, GO:0030210=IEA} carbohydrate metabolic process, cellular process, glycosaminoglycan biosynthetic process, glycosaminoglycan metabolic process, heparan sulfate proteoglycan biosynthetic process, heparin biosynthetic process, regulation of angiotensin levels in blood, small molecule metabolic process Golgi apparatus, Golgi membrane, integral to membrane "heparan sulfate""-glucosamine N-sulfotransferase activity, deacetylase activity, sulfotransferase activity""" Human NDUFA1 Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005739=PMID:16729965, GO:0031966=PMID:17209039, GO:0005747=PMID:12611891, GO:0005743=Reactome:REACT_6310, GO:0006120=PMID:9878551, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0008137=PMID:9878551} O15239 "NADH dehydrogenase ""ubiquinone"" 1 alpha subcomplex subunit 1" protein 20130213 {GO:0022904=TAS, GO:0005739=IDA, GO:0031966=IDA, GO:0005747=IDA, GO:0005743=TAS, GO:0006120=NAS, GO:0044281=TAS, GO:0016021=IEA, GO:0008137=NAS} mitochondrial electron transport, NADH to ubiquinone, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane, mitochondrial membrane, mitochondrial respiratory chain complex I, mitochondrion NADH dehydrogenase (ubiquinone) activity Human NDUFA10 InterPro UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0006139=GO_REF:0000002, GO:0005747=PMID:12611891, GO:0005759=GO_REF:0000039, GO:0042493=GO_REF:0000019, GO:0005743=Reactome:REACT_6310, GO:0006120=PMID:9878551, GO:0016773=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0008137=PMID:9878551, GO:0005524=GO_REF:0000002} Q8WXC9 "NADH dehydrogenase ""ubiquinone"" 1 alpha subcomplex subunit 10, mitochondrial" protein 20130413 {GO:0022904=TAS, GO:0006139=IEA, GO:0005747=IDA, GO:0005759=IEA, GO:0042493=IEA, GO:0005743=TAS, GO:0006120=NAS, GO:0016773=IEA, GO:0044281=TAS, GO:0008137=NAS, GO:0005524=IEA} mitochondrial electron transport, NADH to ubiquinone, nucleobase-containing compound metabolic process, respiratory electron transport chain, response to drug, small molecule metabolic process mitochondrial inner membrane, mitochondrial matrix, mitochondrial respiratory chain complex I ATP binding, NADH dehydrogenase (ubiquinone) activity, phosphotransferase activity, alcohol group as acceptor Human InterPro:IPR002624 NDUFA11 Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005739=GO_REF:0000024, GO:0005747=PMID:12611891, GO:0005743=Reactome:REACT_6310, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037} Q86Y39 "NADH dehydrogenase ""ubiquinone"" 1 alpha subcomplex subunit 11" protein 20130213 {GO:0022904=TAS, GO:0005739=ISS, GO:0005747=IDA, GO:0005743=TAS, GO:0044281=TAS, GO:0016021=IEA} respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane, mitochondrial respiratory chain complex I, mitochondrion Human NDUFA12 HPA UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0003954=GO_REF:0000029, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0005747=PMID:12611891, GO:0007585=PMID:10830904, GO:0016020=GO_REF:0000002, GO:0005743=Reactome:REACT_6310, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0008137=PMID:10830904, GO:0006979=PMID:12857734} Q9UI09 "NADH dehydrogenase ""ubiquinone"" 1 alpha subcomplex subunit 12" protein 20110516 {GO:0022904=TAS, GO:0003954=NAS, GO:0005739=IDA, GO:0005737=IDA, GO:0005747=IDA, GO:0007585=NAS, GO:0016020=IEA, GO:0005743=TAS, GO:0009055=IEA, GO:0044281=TAS, GO:0008137=NAS, GO:0006979=IDA} respiratory electron transport chain, respiratory gaseous exchange, response to oxidative stress, small molecule metabolic process cytoplasm, membrane, mitochondrial inner membrane, mitochondrial respiratory chain complex I, mitochondrion NADH dehydrogenase (ubiquinone) activity, NADH dehydrogenase activity, electron carrier activity Human NDUFA13 HPA UniProtKB {GO:0017148=PMID:12867595, GO:0005515=PMID:17297443, GO:0030308=PMID:16826196, GO:0031966=PMID:17209039, GO:0030262=PMID:10924506, GO:0072593=PMID:16826196, GO:0005743=Reactome:REACT_6310, GO:0044281=Reactome:REACT_111217, GO:0006917=PMID:16826196, GO:0006606=PMID:10924506, GO:0097190=PMID:10924506, GO:0005524=PMID:10924506, GO:0005739=GO_REF:0000052, GO:0022904=Reactome:REACT_22393, GO:0003954=PMID:16826196, GO:0005737=PMID:10924506, GO:0005746=PMID:12611891, GO:0005747=PMID:12611891, GO:0005654=PMID:10924506, GO:0016021=GO_REF:0000037, GO:0008137=PMID:12611891, GO:0045892=PMID:12867595} Q9P0J0 "NADH dehydrogenase ""ubiquinone"" 1 alpha subcomplex subunit 13" protein 20110516 {GO:0017148=IDA, GO:0005515=IPI, GO:0030308=IMP, GO:0031966=IDA, GO:0030262=IDA, GO:0072593=IMP, GO:0005743=TAS, GO:0044281=TAS, GO:0006917=IMP, GO:0006606=NAS, GO:0097190=IDA, GO:0005524=NAS, GO:0005739=IDA, GO:0022904=TAS, GO:0003954=IMP, GO:0005737=IDA, GO:0005746=IDA, GO:0005747=IDA, GO:0005654=IDA, GO:0016021=IEA, GO:0008137=IDA, GO:0045892=IDA} apoptotic nuclear changes, apoptotic signaling pathway, induction of apoptosis, negative regulation of cell growth, negative regulation of transcription, DNA-dependent, negative regulation of translation, protein import into nucleus, reactive oxygen species metabolic process, respiratory electron transport chain, small molecule metabolic process cytoplasm, integral to membrane, mitochondrial inner membrane, mitochondrial membrane, mitochondrial respiratory chain, mitochondrial respiratory chain complex I, mitochondrion, nucleoplasm ATP binding, NADH dehydrogenase (ubiquinone) activity, NADH dehydrogenase activity, protein binding Human NDUFA2 Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0031966=PMID:17209039, GO:0005747=PMID:12611891, GO:0005743=Reactome:REACT_6310, GO:0006120=PMID:9878551, GO:0044281=Reactome:REACT_111217, GO:0008137=PMID:9878551} O43678 "NADH dehydrogenase ""ubiquinone"" 1 alpha subcomplex subunit 2" protein 20130213 {GO:0022904=TAS, GO:0031966=IDA, GO:0005747=IDA, GO:0005743=TAS, GO:0006120=NAS, GO:0044281=TAS, GO:0008137=NAS} mitochondrial electron transport, NADH to ubiquinone, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial membrane, mitochondrial respiratory chain complex I NADH dehydrogenase (ubiquinone) activity Human NDUFA3 Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005747=PMID:12611891, GO:0005743=Reactome:REACT_6310, GO:0006120=PMID:9878551, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0008137=PMID:9878551} O95167 "NADH dehydrogenase ""ubiquinone"" 1 alpha subcomplex subunit 3" protein 20130213 {GO:0022904=TAS, GO:0005747=IDA, GO:0005743=TAS, GO:0006120=NAS, GO:0044281=TAS, GO:0016021=IEA, GO:0008137=NAS} mitochondrial electron transport, NADH to ubiquinone, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane, mitochondrial respiratory chain complex I NADH dehydrogenase (ubiquinone) activity Human NDUFA4 Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005739=PMID:16729965, GO:0005747=PMID:22902835, GO:0004129=PMID:22902835, GO:0005743=Reactome:REACT_6310, GO:0006120=PMID:9878551, GO:0044281=Reactome:REACT_111217, GO:0008137=PMID:9878551, GO:0005751=PMID:22902835} O00483 "NADH dehydrogenase ""ubiquinone"" 1 alpha subcomplex subunit 4" protein 20130213 {GO:0022904=TAS, GO:0005739=IDA, GO:0005747=IDA, GO:0004129=IMP, GO:0005743=TAS, GO:0006120=NAS, GO:0044281=TAS, GO:0008137=NAS, GO:0005751=IDA} mitochondrial electron transport, NADH to ubiquinone, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial respiratory chain complex I, mitochondrial respiratory chain complex IV, mitochondrion NADH dehydrogenase (ubiquinone) activity, cytochrome-c oxidase activity Human NDUFA4L2 null null {} null null null null {} null null null NDUFA5 Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005747=PMID:12611891, GO:0016651=GO_REF:0000002, GO:0006120=PMID:9878551, GO:0005743=Reactome:REACT_6310, GO:0044281=Reactome:REACT_111217, GO:0008137=PMID:9878551} Q16718 "NADH dehydrogenase ""ubiquinone"" 1 alpha subcomplex subunit 5" protein 20130213 {GO:0022904=TAS, GO:0005747=IDA, GO:0016651=IEA, GO:0006120=NAS, GO:0005743=TAS, GO:0044281=TAS, GO:0008137=NAS} mitochondrial electron transport, NADH to ubiquinone, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial respiratory chain complex I NADH dehydrogenase (ubiquinone) activity, oxidoreductase activity, acting on NAD(P)H Human NDUFA6 Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0031966=PMID:17209039, GO:0005747=PMID:12611891, GO:0005743=Reactome:REACT_6310, GO:0006120=PMID:9878551, GO:0044281=Reactome:REACT_111217, GO:0008137=PMID:9878551, GO:0006979=PMID:12857734} P56556 "NADH dehydrogenase ""ubiquinone"" 1 alpha subcomplex subunit 6" protein 20130213 {GO:0022904=TAS, GO:0031966=IDA, GO:0005747=IDA, GO:0005743=TAS, GO:0006120=NAS, GO:0044281=TAS, GO:0008137=NAS, GO:0006979=IDA} mitochondrial electron transport, NADH to ubiquinone, respiratory electron transport chain, response to oxidative stress, small molecule metabolic process mitochondrial inner membrane, mitochondrial membrane, mitochondrial respiratory chain complex I NADH dehydrogenase (ubiquinone) activity Human NDUFA7 Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005747=PMID:12611891, GO:0042773=GO_REF:0000002, GO:0006120=PMID:9878551, GO:0005743=Reactome:REACT_6310, GO:0044281=Reactome:REACT_111217, GO:0008137=PMID:9878551} O95182 "NADH dehydrogenase ""ubiquinone"" 1 alpha subcomplex subunit 7" protein 20130213 {GO:0022904=TAS, GO:0005747=IDA, GO:0042773=IEA, GO:0006120=NAS, GO:0005743=TAS, GO:0044281=TAS, GO:0008137=NAS} ATP synthesis coupled electron transport, mitochondrial electron transport, NADH to ubiquinone, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial respiratory chain complex I NADH dehydrogenase (ubiquinone) activity Human NDUFA8 HPA UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005739=GO_REF:0000052, GO:0005758=PMID:21310150, GO:0005747=PMID:12611891, GO:0005743=Reactome:REACT_6310, GO:0006120=PMID:9878551, GO:0044281=Reactome:REACT_111217, GO:0008137=PMID:9878551} P51970 "NADH dehydrogenase ""ubiquinone"" 1 alpha subcomplex subunit 8" protein 20111111 {GO:0022904=TAS, GO:0005739=IDA, GO:0005758=IDA, GO:0005747=IDA, GO:0005743=TAS, GO:0006120=NAS, GO:0044281=TAS, GO:0008137=NAS} mitochondrial electron transport, NADH to ubiquinone, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial respiratory chain complex I, mitochondrion NADH dehydrogenase (ubiquinone) activity Human NDUFA9 IntAct UniProtKB {GO:0005515=PMID:22309213, GO:0050662=GO_REF:0000002, GO:0006694=GO_REF:0000002, GO:0031966=PMID:17209039, GO:0005743=Reactome:REACT_6310, GO:0044281=Reactome:REACT_111217, GO:0003854=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0022904=Reactome:REACT_22393, GO:0003954=PMID:11112787, GO:0004672=GO_REF:0000002, GO:0005747=PMID:12611891, GO:0005759=PMID:8486360, GO:0006120=PMID:9878551, GO:0008137=PMID:9878551, GO:0006814=PMID:8486360} Q16795 "NADH dehydrogenase ""ubiquinone"" 1 alpha subcomplex subunit 9, mitochondrial" protein 20130415 {GO:0005515=IPI, GO:0050662=IEA, GO:0006694=IEA, GO:0031966=IDA, GO:0005743=TAS, GO:0044281=TAS, GO:0003854=IEA, GO:0005524=IEA, GO:0022904=TAS, GO:0003954=IMP, GO:0004672=IEA, GO:0005747=IDA, GO:0005759=IDA, GO:0006120=NAS, GO:0008137=NAS, GO:0006814=NAS} mitochondrial electron transport, NADH to ubiquinone, respiratory electron transport chain, small molecule metabolic process, sodium ion transport, steroid biosynthetic process mitochondrial inner membrane, mitochondrial matrix, mitochondrial membrane, mitochondrial respiratory chain complex I 3-beta-hydroxy-delta5-steroid dehydrogenase activity, ATP binding, NADH dehydrogenase (ubiquinone) activity, NADH dehydrogenase activity, coenzyme binding, protein binding, protein kinase activity Human UniProtKB:P78537 NDUFAB1 Reactome UniProtKB {GO:0005504=GO_REF:0000024, GO:0031966=GO_REF:0000024, GO:0000036=PMID:10234612, GO:0009249=PMID:21846720, GO:0005509=PMID:10234612, GO:0005743=Reactome:REACT_6310, GO:0044281=Reactome:REACT_111217, GO:0005739=GO_REF:0000019, GO:0022904=Reactome:REACT_22393, GO:0005747=PMID:12611891, GO:0005759=GO_REF:0000024, GO:0006120=PMID:9878551, GO:0006633=PMID:10234612, GO:0008137=PMID:9878551} O14561 Acyl carrier protein, mitochondrial protein 20050510 {GO:0005504=ISS, GO:0031966=ISS, GO:0000036=NAS, GO:0009249=IMP, GO:0005509=NAS, GO:0005743=TAS, GO:0044281=TAS, GO:0005739=IEA, GO:0022904=TAS, GO:0005747=IDA, GO:0005759=ISS, GO:0006120=NAS, GO:0006633=NAS, GO:0008137=NAS} fatty acid biosynthetic process, mitochondrial electron transport, NADH to ubiquinone, protein lipoylation, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial matrix, mitochondrial membrane, mitochondrial respiratory chain complex I, mitochondrion ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process, NADH dehydrogenase (ubiquinone) activity, calcium ion binding, fatty acid binding Human NDUFAF1 HPA UniProtKB {GO:0005515=PMID:17344420, GO:0005739=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0005747=PMID:11935339, GO:0006461=PMID:11935339, GO:0006120=PMID:11935339, GO:0051082=PMID:11935339} Q9Y375 Complex I intermediate-associated protein 30, mitochondrial protein 20111111 {GO:0005515=IPI, GO:0005739=IEA, GO:0005737=IDA, GO:0005747=NAS, GO:0006461=NAS, GO:0006120=NAS, GO:0051082=NAS} mitochondrial electron transport, NADH to ubiquinone, protein complex assembly cytoplasm, mitochondrial respiratory chain complex I, mitochondrion protein binding, unfolded protein binding Human NDUFAF2 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0009055=GO_REF:0000002, GO:0008137=GO_REF:0000002} Q8N183 Mimitin, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0016020=IEA, GO:0009055=IEA, GO:0008137=IEA} membrane, mitochondrion NADH dehydrogenase (ubiquinone) activity, electron carrier activity Human UniProtKB-SubCell:SL-0173 NDUFAF3 LIFEdb UniProtKB {GO:0005515=PMID:19463981, GO:0032981=PMID:19463981, GO:0005743=PMID:19463981, GO:0005634=GO_REF:0000054} Q9BU61 "NADH dehydrogenase ""ubiquinone"" 1 alpha subcomplex assembly factor 3" protein 20100607 {GO:0005515=IPI, GO:0032981=IMP, GO:0005743=IDA, GO:0005634=IDA} mitochondrial respiratory chain complex I assembly mitochondrial inner membrane, nucleus protein binding Human NDUFAF4 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005515=PMID:19463981, GO:0032981=PMID:18179882, GO:0005516=GO_REF:0000037, GO:0031966=PMID:19463981} Q9P032 "NADH dehydrogenase ""ubiquinone"" 1 alpha subcomplex assembly factor 4" protein 20120912 {GO:0005739=IDA, GO:0005515=IPI, GO:0032981=IMP, GO:0005516=IEA, GO:0031966=IDA} mitochondrial respiratory chain complex I assembly mitochondrial membrane, mitochondrion calmodulin binding, protein binding Human NDUFB1 Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005747=PMID:12611891, GO:0005743=Reactome:REACT_6310, GO:0006120=PMID:9878551, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0008137=PMID:9878551} O75438 "NADH dehydrogenase ""ubiquinone"" 1 beta subcomplex subunit 1" protein 20130213 {GO:0022904=TAS, GO:0005747=IDA, GO:0005743=TAS, GO:0006120=NAS, GO:0044281=TAS, GO:0016021=IEA, GO:0008137=NAS} mitochondrial electron transport, NADH to ubiquinone, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane, mitochondrial respiratory chain complex I NADH dehydrogenase (ubiquinone) activity Human NDUFB10 Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005515=PMID:14557246, GO:0005747=PMID:12611891, GO:0005743=Reactome:REACT_6310, GO:0006120=PMID:9878551, GO:0044281=Reactome:REACT_111217, GO:0008137=PMID:9878551} O96000 "NADH dehydrogenase ""ubiquinone"" 1 beta subcomplex subunit 10" protein 20130213 {GO:0022904=TAS, GO:0005515=IPI, GO:0005747=IDA, GO:0005743=TAS, GO:0006120=NAS, GO:0044281=TAS, GO:0008137=NAS} mitochondrial electron transport, NADH to ubiquinone, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial respiratory chain complex I NADH dehydrogenase (ubiquinone) activity, protein binding Human NDUFB11 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0022904=Reactome:REACT_22393, GO:0005747=PMID:12611891, GO:0005743=Reactome:REACT_6310, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037} Q9NX14 "NADH dehydrogenase ""ubiquinone"" 1 beta subcomplex subunit 11, mitochondrial" protein 20111111 {GO:0005739=IDA, GO:0022904=TAS, GO:0005747=IDA, GO:0005743=TAS, GO:0044281=TAS, GO:0016021=IEA} respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane, mitochondrial respiratory chain complex I, mitochondrion Human NDUFB2 Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005747=PMID:12611891, GO:0005743=Reactome:REACT_6310, GO:0006120=PMID:9878551, GO:0044281=Reactome:REACT_111217, GO:0008137=PMID:9878551} O95178 "NADH dehydrogenase ""ubiquinone"" 1 beta subcomplex subunit 2, mitochondrial" protein 20050510 {GO:0022904=TAS, GO:0005747=IDA, GO:0005743=TAS, GO:0006120=NAS, GO:0044281=TAS, GO:0008137=NAS} mitochondrial electron transport, NADH to ubiquinone, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial respiratory chain complex I NADH dehydrogenase (ubiquinone) activity Human NDUFB3 Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005747=PMID:12611891, GO:0006120=PMID:9878551, GO:0005743=Reactome:REACT_6310, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0008137=PMID:9878551} O43676 "NADH dehydrogenase ""ubiquinone"" 1 beta subcomplex subunit 3" protein 20130213 {GO:0022904=TAS, GO:0005747=IDA, GO:0006120=NAS, GO:0005743=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0008137=NAS} mitochondrial electron transport, NADH to ubiquinone, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane, mitochondrial respiratory chain complex I NADH dehydrogenase (ubiquinone) activity Human NDUFB4 Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005739=GO_REF:0000002, GO:0005747=PMID:12611891, GO:0005743=Reactome:REACT_6310, GO:0006120=PMID:9878551, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0008137=PMID:9878551, GO:0006979=PMID:12857734} O95168 "NADH dehydrogenase ""ubiquinone"" 1 beta subcomplex subunit 4" protein 20130213 {GO:0022904=TAS, GO:0005739=IEA, GO:0005747=IDA, GO:0005743=TAS, GO:0006120=NAS, GO:0044281=TAS, GO:0016021=IEA, GO:0008137=NAS, GO:0006979=IDA} mitochondrial electron transport, NADH to ubiquinone, respiratory electron transport chain, response to oxidative stress, small molecule metabolic process integral to membrane, mitochondrial inner membrane, mitochondrial respiratory chain complex I, mitochondrion NADH dehydrogenase (ubiquinone) activity Human NDUFB5 HPA UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005739=GO_REF:0000052, GO:0005747=PMID:12611891, GO:0005743=Reactome:REACT_6310, GO:0006120=PMID:9878551, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0008137=PMID:9878551} O43674 "NADH dehydrogenase ""ubiquinone"" 1 beta subcomplex subunit 5, mitochondrial" protein 20080205 {GO:0022904=TAS, GO:0005739=IDA, GO:0005747=IDA, GO:0005743=TAS, GO:0006120=NAS, GO:0044281=TAS, GO:0016021=IEA, GO:0008137=NAS} mitochondrial electron transport, NADH to ubiquinone, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane, mitochondrial respiratory chain complex I, mitochondrion NADH dehydrogenase (ubiquinone) activity Human NDUFB6 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0022904=Reactome:REACT_22393, GO:0031966=PMID:17209039, GO:0005747=PMID:12611891, GO:0005730=GO_REF:0000052, GO:0005743=Reactome:REACT_6310, GO:0006120=PMID:9878551, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0008137=PMID:9878551} O95139 "NADH dehydrogenase ""ubiquinone"" 1 beta subcomplex subunit 6" protein 20111111 {GO:0005739=IDA, GO:0022904=TAS, GO:0031966=IDA, GO:0005747=IDA, GO:0005730=IDA, GO:0005743=TAS, GO:0006120=NAS, GO:0005634=IDA, GO:0044281=TAS, GO:0016021=IEA, GO:0008137=NAS} mitochondrial electron transport, NADH to ubiquinone, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane, mitochondrial membrane, mitochondrial respiratory chain complex I, mitochondrion, nucleolus, nucleus NADH dehydrogenase (ubiquinone) activity Human NDUFB7 Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005758=PMID:21310150, GO:0005747=PMID:12611891, GO:0005743=Reactome:REACT_6310, GO:0006120=PMID:9878551, GO:0044281=Reactome:REACT_111217, GO:0008137=PMID:9878551} P17568 "NADH dehydrogenase ""ubiquinone"" 1 beta subcomplex subunit 7" protein 20130213 {GO:0022904=TAS, GO:0005758=IDA, GO:0005747=IDA, GO:0005743=TAS, GO:0006120=NAS, GO:0044281=TAS, GO:0008137=NAS} mitochondrial electron transport, NADH to ubiquinone, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial respiratory chain complex I NADH dehydrogenase (ubiquinone) activity Human NDUFB8 HPA UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005739=GO_REF:0000052, GO:0005747=PMID:12611891, GO:0005783=GO_REF:0000054, GO:0005743=Reactome:REACT_6310, GO:0006120=PMID:9878551, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0008137=GO_REF:0000002} Q5W145 "NADH dehydrogenase ""ubiquinone"" 1 beta subcomplex subunit 8, mitochondrial" protein 20080205 {GO:0022904=TAS, GO:0005739=IDA, GO:0005747=IDA, GO:0005783=IDA, GO:0005743=TAS, GO:0006120=NAS, GO:0044281=TAS, GO:0016021=IEA, GO:0008137=IEA} mitochondrial electron transport, NADH to ubiquinone, respiratory electron transport chain, small molecule metabolic process endoplasmic reticulum, integral to membrane, mitochondrial inner membrane, mitochondrial respiratory chain complex I, mitochondrion NADH dehydrogenase (ubiquinone) activity Human NDUFB9 HPA UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005739=GO_REF:0000052, GO:0005747=PMID:12611891, GO:0007605=PMID:8661098, GO:0005743=Reactome:REACT_6310, GO:0006120=PMID:9878551, GO:0044281=Reactome:REACT_111217, GO:0008137=PMID:9878551} Q9Y6M9 "NADH dehydrogenase ""ubiquinone"" 1 beta subcomplex subunit 9" protein 20110516 {GO:0022904=TAS, GO:0005739=IDA, GO:0005747=IDA, GO:0007605=TAS, GO:0005743=TAS, GO:0006120=NAS, GO:0044281=TAS, GO:0008137=NAS} mitochondrial electron transport, NADH to ubiquinone, respiratory electron transport chain, sensory perception of sound, small molecule metabolic process mitochondrial inner membrane, mitochondrial respiratory chain complex I, mitochondrion NADH dehydrogenase (ubiquinone) activity Human NDUFC1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0022904=Reactome:REACT_22393, GO:0005747=PMID:9878551, GO:0005743=Reactome:REACT_6310, GO:0006120=PMID:9878551, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0008137=PMID:9878551} O43677 "NADH dehydrogenase ""ubiquinone"" 1 subunit C1, mitochondrial" protein 20111111 {GO:0005739=IDA, GO:0022904=TAS, GO:0005747=NAS, GO:0005743=TAS, GO:0006120=NAS, GO:0044281=TAS, GO:0016021=IEA, GO:0008137=NAS} mitochondrial electron transport, NADH to ubiquinone, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane, mitochondrial respiratory chain complex I, mitochondrion NADH dehydrogenase (ubiquinone) activity Human NDUFC2 LIFEdb UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005737=GO_REF:0000054, GO:0005747=PMID:12611891, GO:0070469=GO_REF:0000038, GO:0005743=Reactome:REACT_6310, GO:0006120=PMID:9878551, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0008137=PMID:9878551} O95298 "NADH dehydrogenase ""ubiquinone"" 1 subunit C2" protein 20100607 {GO:0022904=TAS, GO:0005737=IDA, GO:0005747=IDA, GO:0070469=IEA, GO:0005743=TAS, GO:0006120=NAS, GO:0044281=TAS, GO:0016021=IEA, GO:0008137=NAS} mitochondrial electron transport, NADH to ubiquinone, respiratory electron transport chain, small molecule metabolic process cytoplasm, integral to membrane, mitochondrial inner membrane, mitochondrial respiratory chain complex I, respiratory chain NADH dehydrogenase (ubiquinone) activity Human NDUFS1 Reactome UniProtKB {GO:0005515=PMID:15186778, GO:0051539=GO_REF:0000037, GO:0046034=PMID:15186778, GO:0051536=GO_REF:0000002, GO:0051537=GO_REF:0000037, GO:0072593=PMID:15186778, GO:0005743=Reactome:REACT_6310, GO:0051881=PMID:15186778, GO:0006915=PMID:15186778, GO:0009055=PMID:1935949, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0022904=Reactome:REACT_22393, GO:0005739=GO_REF:0000019, GO:0005758=PMID:15186778, GO:0045333=PMID:15186778, GO:0042773=GO_REF:0000002, GO:0005747=PMID:12611891, GO:0016020=GO_REF:0000002, GO:0006120=PMID:9878551, GO:0008137=PMID:16870178} P28331 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial protein 20050510 {GO:0005515=IPI, GO:0051539=IEA, GO:0046034=IMP, GO:0051536=IEA, GO:0051537=IEA, GO:0072593=IMP, GO:0005743=TAS, GO:0051881=IMP, GO:0006915=IDA, GO:0009055=NAS, GO:0044281=TAS, GO:0046872=IEA, GO:0022904=TAS, GO:0005739=IEA, GO:0005758=IDA, GO:0045333=IMP, GO:0042773=IEA, GO:0005747=IDA, GO:0016020=IEA, GO:0006120=NAS, GO:0008137=IMP} ATP metabolic process, ATP synthesis coupled electron transport, apoptotic process, cellular respiration, mitochondrial electron transport, NADH to ubiquinone, reactive oxygen species metabolic process, regulation of mitochondrial membrane potential, respiratory electron transport chain, small molecule metabolic process membrane, mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial respiratory chain complex I, mitochondrion 2 iron, 2 sulfur cluster binding, 4 iron, 4 sulfur cluster binding, NADH dehydrogenase (ubiquinone) activity, electron carrier activity, iron-sulfur cluster binding, metal ion binding, protein binding Human NDUFS2 IntAct UniProtKB {GO:0005515=PMID:19688755, GO:0048038=GO_REF:0000002, GO:0051539=GO_REF:0000037, GO:0005743=Reactome:REACT_6310, GO:0009055=PMID:9647766, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0022904=Reactome:REACT_22393, GO:0005739=PMID:9585441, GO:0003954=PMID:14749350, GO:0051287=GO_REF:0000002, GO:0005747=PMID:12611891, GO:0016651=GO_REF:0000002, GO:0006120=PMID:9878551, GO:0008137=PMID:9878551, GO:0006979=PMID:12857734} O75306 "NADH dehydrogenase ""ubiquinone"" iron-sulfur protein 2, mitochondrial" protein 20130415 {GO:0005515=IPI, GO:0048038=IEA, GO:0051539=IEA, GO:0005743=TAS, GO:0009055=NAS, GO:0044281=TAS, GO:0046872=IEA, GO:0022904=TAS, GO:0005739=IDA, GO:0003954=IMP, GO:0051287=IEA, GO:0005747=IDA, GO:0016651=IEA, GO:0006120=NAS, GO:0008137=NAS, GO:0006979=IDA} mitochondrial electron transport, NADH to ubiquinone, respiratory electron transport chain, response to oxidative stress, small molecule metabolic process mitochondrial inner membrane, mitochondrial respiratory chain complex I, mitochondrion 4 iron, 4 sulfur cluster binding, NAD binding, NADH dehydrogenase (ubiquinone) activity, NADH dehydrogenase activity, electron carrier activity, metal ion binding, oxidoreductase activity, acting on NAD(P)H, protein binding, quinone binding Human UniProtKB:O75489 NDUFS3 IntAct UniProtKB {GO:0005515=PMID:19688755, GO:0030308=PMID:16826196, GO:0031966=PMID:17209039, GO:0072593=PMID:16826196, GO:0005743=Reactome:REACT_6310, GO:0009055=PMID:9647766, GO:0044281=Reactome:REACT_111217, GO:0006917=PMID:16826196, GO:0003954=PMID:11112787, GO:0005739=PMID:9647766, GO:0022904=Reactome:REACT_22393, GO:0005747=PMID:12611891, GO:0006120=PMID:9878551, GO:0008137=PMID:9878551} O75489 "NADH dehydrogenase ""ubiquinone"" iron-sulfur protein 3, mitochondrial" protein 20130415 {GO:0005515=IPI, GO:0030308=IMP, GO:0031966=IDA, GO:0072593=IMP, GO:0005743=TAS, GO:0009055=NAS, GO:0044281=TAS, GO:0006917=IMP, GO:0003954=IMP, GO:0005739=NAS, GO:0022904=TAS, GO:0005747=IDA, GO:0006120=NAS, GO:0008137=NAS} induction of apoptosis, mitochondrial electron transport, NADH to ubiquinone, negative regulation of cell growth, reactive oxygen species metabolic process, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial membrane, mitochondrial respiratory chain complex I, mitochondrion NADH dehydrogenase (ubiquinone) activity, NADH dehydrogenase activity, electron carrier activity, protein binding Human UniProtKB:O75306 NDUFS4 HPA UniProtKB {GO:0072593=PMID:16870178, GO:0005743=Reactome:REACT_6310, GO:0044281=Reactome:REACT_111217, GO:0048146=PMID:16478720, GO:0051591=PMID:11181577, GO:0005739=GO_REF:0000052, GO:0022904=Reactome:REACT_22393, GO:0032981=PMID:15038602, GO:0045333=PMID:16478720, GO:0005747=PMID:12611891, GO:0007420=PMID:14765537, GO:0016651=GO_REF:0000002, GO:0019933=PMID:11181577, GO:0006120=PMID:9878551, GO:0001932=PMID:11165261, GO:0022900=GO_REF:0000002, GO:0008137=PMID:16478720} O43181 "NADH dehydrogenase ""ubiquinone"" iron-sulfur protein 4, mitochondrial" protein 20080205 {GO:0072593=IMP, GO:0005743=TAS, GO:0044281=TAS, GO:0048146=IMP, GO:0051591=IMP, GO:0005739=IDA, GO:0022904=TAS, GO:0032981=IMP, GO:0045333=IMP, GO:0005747=IDA, GO:0007420=IMP, GO:0016651=IEA, GO:0019933=IMP, GO:0006120=NAS, GO:0001932=IMP, GO:0022900=IEA, GO:0008137=IMP} brain development, cAMP-mediated signaling, cellular respiration, electron transport chain, mitochondrial electron transport, NADH to ubiquinone, mitochondrial respiratory chain complex I assembly, positive regulation of fibroblast proliferation, reactive oxygen species metabolic process, regulation of protein phosphorylation, respiratory electron transport chain, response to cAMP, small molecule metabolic process mitochondrial inner membrane, mitochondrial respiratory chain complex I, mitochondrion NADH dehydrogenase (ubiquinone) activity, oxidoreductase activity, acting on NAD(P)H Human NDUFS5 Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005739=PMID:16826196, GO:0032981=PMID:11112787, GO:0005758=GO_REF:0000039, GO:0005747=PMID:12611891, GO:0005743=Reactome:REACT_6310, GO:0006120=PMID:9878551, GO:0044281=Reactome:REACT_111217, GO:0008137=PMID:9878551} O43920 "NADH dehydrogenase ""ubiquinone"" iron-sulfur protein 5" protein 20130213 {GO:0022904=TAS, GO:0005739=IDA, GO:0032981=IMP, GO:0005758=IEA, GO:0005747=IDA, GO:0005743=TAS, GO:0006120=NAS, GO:0044281=TAS, GO:0008137=NAS} mitochondrial electron transport, NADH to ubiquinone, mitochondrial respiratory chain complex I assembly, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial respiratory chain complex I, mitochondrion NADH dehydrogenase (ubiquinone) activity Human NDUFS6 Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005747=PMID:12611891, GO:0005743=Reactome:REACT_6310, GO:0006120=PMID:9878551, GO:0009055=PMID:9647766, GO:0044281=Reactome:REACT_111217, GO:0008137=PMID:9878551} O75380 "NADH dehydrogenase ""ubiquinone"" iron-sulfur protein 6, mitochondrial" protein 20050510 {GO:0022904=TAS, GO:0005747=IDA, GO:0005743=TAS, GO:0006120=NAS, GO:0009055=NAS, GO:0044281=TAS, GO:0008137=NAS} mitochondrial electron transport, NADH to ubiquinone, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial respiratory chain complex I NADH dehydrogenase (ubiquinone) activity, electron carrier activity Human NDUFS7 Reactome UniProtKB {GO:0005515=PMID:15186778, GO:0043005=GO_REF:0000019, GO:0048038=GO_REF:0000002, GO:0051539=GO_REF:0000037, GO:0005743=Reactome:REACT_6310, GO:0044281=Reactome:REACT_111217, GO:0002020=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0022904=Reactome:REACT_22393, GO:0003954=PMID:14749350, GO:0032981=PMID:11112787, GO:0016655=PMID:8938450, GO:0005747=PMID:12611891, GO:0097060=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0006120=PMID:9878551, GO:0008137=PMID:9878551} O75251 "NADH dehydrogenase ""ubiquinone"" iron-sulfur protein 7, mitochondrial" protein 20050510 {GO:0005515=IPI, GO:0043005=IEA, GO:0048038=IEA, GO:0051539=IEA, GO:0005743=TAS, GO:0044281=TAS, GO:0002020=IEA, GO:0046872=IEA, GO:0022904=TAS, GO:0003954=IMP, GO:0032981=IMP, GO:0016655=NAS, GO:0005747=IDA, GO:0097060=IEA, GO:0043025=IEA, GO:0006120=NAS, GO:0008137=NAS} mitochondrial electron transport, NADH to ubiquinone, mitochondrial respiratory chain complex I assembly, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial respiratory chain complex I, neuron projection, neuronal cell body, synaptic membrane 4 iron, 4 sulfur cluster binding, NADH dehydrogenase (ubiquinone) activity, NADH dehydrogenase activity, metal ion binding, oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor, protease binding, protein binding, quinone binding Human NDUFS8 ENSEMBL UniProtKB {GO:0051539=GO_REF:0000038, GO:0051536=GO_REF:0000002, GO:0005743=Reactome:REACT_6310, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000038, GO:0022904=Reactome:REACT_22393, GO:0005739=GO_REF:0000019, GO:0003954=PMID:14749350, GO:0032981=PMID:11112787, GO:0005747=PMID:12611891, GO:0016020=GO_REF:0000002, GO:0016651=GO_REF:0000002, GO:0016491=GO_REF:0000002, GO:0006120=PMID:9878551, GO:0008137=PMID:9878551, GO:0006979=PMID:12857734} Q08E91 NDUFS8 protein protein 20130413 {GO:0051539=IEA, GO:0051536=IEA, GO:0005743=TAS, GO:0009055=IEA, GO:0044281=TAS, GO:0046872=IEA, GO:0022904=TAS, GO:0005739=IEA, GO:0003954=IMP, GO:0032981=IMP, GO:0005747=IDA, GO:0016020=IEA, GO:0016651=IEA, GO:0016491=IEA, GO:0006120=NAS, GO:0008137=NAS, GO:0006979=IDA} mitochondrial electron transport, NADH to ubiquinone, mitochondrial respiratory chain complex I assembly, respiratory electron transport chain, response to oxidative stress, small molecule metabolic process membrane, mitochondrial inner membrane, mitochondrial respiratory chain complex I, mitochondrion 4 iron, 4 sulfur cluster binding, NADH dehydrogenase (ubiquinone) activity, NADH dehydrogenase activity, electron carrier activity, iron-sulfur cluster binding, metal ion binding, oxidoreductase activity, oxidoreductase activity, acting on NAD(P)H Human Ensembl:ENSMUSP00000074600 NDUFV1 Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0005747=PMID:12611891, GO:0051287=GO_REF:0000002, GO:0051539=GO_REF:0000037, GO:0010181=GO_REF:0000002, GO:0016651=GO_REF:0000002, GO:0006120=PMID:9878551, GO:0005743=Reactome:REACT_6310, GO:0044281=Reactome:REACT_111217, GO:0008137=PMID:8288251, GO:0046872=GO_REF:0000037} P49821 "NADH dehydrogenase ""ubiquinone"" flavoprotein 1, mitochondrial" protein 20050510 {GO:0022904=TAS, GO:0005747=IDA, GO:0051287=IEA, GO:0051539=IEA, GO:0010181=IEA, GO:0016651=IEA, GO:0006120=NAS, GO:0005743=TAS, GO:0044281=TAS, GO:0008137=NAS, GO:0046872=IEA} mitochondrial electron transport, NADH to ubiquinone, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial respiratory chain complex I 4 iron, 4 sulfur cluster binding, FMN binding, NAD binding, NADH dehydrogenase (ubiquinone) activity, metal ion binding, oxidoreductase activity, acting on NAD(P)H Human NDUFV2 Reactome UniProtKB {GO:0051537=GO_REF:0000037, GO:0005743=Reactome:REACT_6310, GO:0009055=PMID:7488192, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0007399=PMID:9570948, GO:0005739=PMID:12754703, GO:0048738=PMID:12754703, GO:0022904=Reactome:REACT_22393, GO:0005747=PMID:12611891, GO:0016491=GO_REF:0000002, GO:0006120=PMID:12754703, GO:0008137=PMID:9570948} P19404 "NADH dehydrogenase ""ubiquinone"" flavoprotein 2, mitochondrial" protein 20050510 {GO:0051537=IEA, GO:0005743=TAS, GO:0009055=NAS, GO:0044281=TAS, GO:0046872=IEA, GO:0007399=IMP, GO:0005739=IDA, GO:0048738=IMP, GO:0022904=TAS, GO:0005747=IDA, GO:0016491=IEA, GO:0006120=IMP, GO:0008137=NAS} cardiac muscle tissue development, mitochondrial electron transport, NADH to ubiquinone, nervous system development, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial respiratory chain complex I, mitochondrion 2 iron, 2 sulfur cluster binding, NADH dehydrogenase (ubiquinone) activity, electron carrier activity, metal ion binding, oxidoreductase activity Human NDUFV3 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0022904=Reactome:REACT_22393, GO:0005747=PMID:12611891, GO:0005730=GO_REF:0000052, GO:0005743=Reactome:REACT_6310, GO:0006120=PMID:9878551, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0008137=PMID:9878551} P56181 "NADH dehydrogenase ""ubiquinone"" flavoprotein 3, mitochondrial" protein 20100326 {GO:0005739=IDA, GO:0022904=TAS, GO:0005747=IDA, GO:0005730=IDA, GO:0005743=TAS, GO:0006120=NAS, GO:0005634=IDA, GO:0044281=TAS, GO:0008137=NAS} mitochondrial electron transport, NADH to ubiquinone, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial respiratory chain complex I, mitochondrion, nucleolus, nucleus NADH dehydrogenase (ubiquinone) activity Human NEB Reactome UniProtKB {GO:0030832=PMID:7739042, GO:0030018=PMID:9501083, GO:0030049=Reactome:REACT_16969, GO:0007517=PMID:7739042, GO:0003779=GO_REF:0000037, GO:0015629=PMID:7739042, GO:0008307=PMID:7739042, GO:0005829=Reactome:REACT_17057, GO:0007525=PMID:7739042} P20929 Nebulin protein 20090210 {GO:0030832=NAS, GO:0030018=IDA, GO:0030049=TAS, GO:0007517=TAS, GO:0003779=IEA, GO:0015629=TAS, GO:0008307=TAS, GO:0005829=TAS, GO:0007525=NAS} muscle filament sliding, muscle organ development, regulation of actin filament length, somatic muscle development Z disc, actin cytoskeleton, cytosol actin binding, structural constituent of muscle Human NEBL BHF-UCL UniProtKB {GO:0005515=PMID:11309420, GO:0008092=PMID:17987659, GO:0071691=PMID:11822876, GO:0001725=PMID:10470015, GO:0030018=PMID:20951326, GO:0051015=PMID:10470015, GO:0031005=PMID:17987659, GO:0005523=PMID:17987659, GO:0008307=PMID:9733644, GO:0031674=PMID:9733644} O76041 Nebulette protein 20110808 {GO:0005515=IPI, GO:0008092=IPI, GO:0071691=IMP, GO:0001725=IDA, GO:0030018=IDA, GO:0051015=IDA, GO:0031005=IPI, GO:0005523=IPI, GO:0008307=NAS, GO:0031674=NAS} cardiac muscle thin filament assembly I band, Z disc, stress fiber actin filament binding, cytoskeletal protein binding, filamin binding, protein binding, structural constituent of muscle, tropomyosin binding Human UniProtKB:Q86TC9 NECAB1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005509=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0043231=GO_REF:0000052} Q8N987 N-terminal EF-hand calcium-binding protein 1 protein 20101115 {GO:0005737=IDA, GO:0005509=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0043231=IDA} cytoplasm, intracellular membrane-bounded organelle, nucleolus, nucleus calcium ion binding Human NECAB2 IntAct UniProtKB {GO:0005515=PMID:17689978, GO:0005737=GO_REF:0000039, GO:0005509=GO_REF:0000002} Q7Z6G3 N-terminal EF-hand calcium-binding protein 2 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0005509=IEA} cytoplasm calcium ion binding, protein binding Human UniProtKB:P29274 NECAB3 UniProtKB UniProtKB {GO:0005515=PMID:10833507, GO:0000137=PMID:10833507, GO:0005737=PMID:10833507, GO:0009306=PMID:12780348, GO:0005509=GO_REF:0000002, GO:0005789=PMID:10833507, GO:0005634=PMID:10833507, GO:0042984=PMID:10833507, GO:0019538=PMID:12780348} Q96P71 N-terminal EF-hand calcium-binding protein 3 protein 20031103 {GO:0005515=IPI, GO:0000137=IDA, GO:0005737=IDA, GO:0009306=NAS, GO:0005509=IEA, GO:0005789=IDA, GO:0005634=NAS, GO:0042984=IDA, GO:0019538=IDA} protein metabolic process, protein secretion, regulation of amyloid precursor protein biosynthetic process Golgi cis cisterna, cytoplasm, endoplasmic reticulum membrane, nucleus calcium ion binding, protein binding Human NECAP1 UniProtKB UniProtKB {GO:0030125=GO_REF:0000019, GO:0005905=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0015031=GO_REF:0000037, GO:0006897=GO_REF:0000019} Q8NC96 Adaptin ear-binding coat-associated protein 1 protein 20130413 {GO:0030125=IEA, GO:0005905=IEA, GO:0005886=IEA, GO:0016020=IEA, GO:0015031=IEA, GO:0006897=IEA} endocytosis, protein transport clathrin vesicle coat, coated pit, membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 NECAP2 LIFEdb UniProtKB {GO:0005622=GO_REF:0000054, GO:0030125=GO_REF:0000024, GO:0005905=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0015031=GO_REF:0000037, GO:0006897=GO_REF:0000024} Q9NVZ3 Adaptin ear-binding coat-associated protein 2 protein 20100607 {GO:0005622=IDA, GO:0030125=ISS, GO:0005905=ISS, GO:0005886=IEA, GO:0016020=IEA, GO:0015031=IEA, GO:0006897=ISS} endocytosis, protein transport clathrin vesicle coat, coated pit, intracellular, membrane, plasma membrane Human NEDD1 Reactome UniProtKB {GO:0005813=PMID:21399614, GO:0007067=GO_REF:0000037, GO:0000922=GO_REF:0000019, GO:0005814=GO_REF:0000019, GO:0000086=Reactome:REACT_2203, GO:0045177=GO_REF:0000019, GO:0005932=GO_REF:0000019, GO:0000278=Reactome:REACT_152, GO:0000242=GO_REF:0000019, GO:0005829=Reactome:REACT_15470, GO:0051301=GO_REF:0000037} Q8NHV4 Protein NEDD1 protein 20130213 {GO:0005813=IDA, GO:0007067=IEA, GO:0000922=IEA, GO:0005814=IEA, GO:0000086=TAS, GO:0045177=IEA, GO:0005932=IEA, GO:0000278=TAS, GO:0000242=IEA, GO:0005829=TAS, GO:0051301=IEA} G2/M transition of mitotic cell cycle, cell division, mitosis, mitotic cell cycle apical part of cell, centriole, centrosome, cytosol, microtubule basal body, pericentriolar material, spindle pole Human NEDD4 BHF-UCL UniProtKB {GO:0005515=PMID:9305852, GO:0043130=PMID:9990509, GO:0004842=PMID:20086093, GO:0006513=GO_REF:0000019, GO:0019221=Reactome:REACT_25229, GO:0031698=PMID:18544533, GO:0031175=PMID:9990509, GO:0005622=GO_REF:0000002, GO:0031623=PMID:18544533, GO:0070534=GO_REF:0000024, GO:0034644=PMID:17996703, GO:0042787=PMID:20086093, GO:0010766=PMID:10642508, GO:0010768=PMID:17996703, GO:0070063=PMID:17996703, GO:0005938=PMID:9990509, GO:0070064=PMID:15126635, GO:0000785=PMID:17996703, GO:0050847=PMID:8649367, GO:0005794=PMID:16118794, GO:0019904=PMID:12907594, GO:0014068=PMID:17218260, GO:1901016=PMID:17289006, GO:0051592=PMID:9405440, GO:0042110=GO_REF:0000019, GO:0050807=GO_REF:0000019, GO:0042921=PMID:8649367, GO:0007041=PMID:18544533, GO:0030948=GO_REF:0000024, GO:0044111=PMID:15126635, GO:0045732=PMID:14973438, GO:0048471=PMID:9990509, GO:0005886=PMID:15126635, GO:0048514=GO_REF:0000019, GO:0000151=GO_REF:0000024, GO:0005634=GO_REF:0000033, GO:0005829=PMID:9405440, GO:0050815=GO_REF:0000024, GO:0050816=GO_REF:0000024, GO:0005737=PMID:12796489, GO:0007528=GO_REF:0000019, GO:0042391=PMID:17289006, GO:0034765=PMID:17289006, GO:0046824=PMID:17218261, GO:0019089=PMID:15126635, GO:0003197=GO_REF:0000019, GO:0003151=GO_REF:0000019, GO:0016327=PMID:9405440, GO:0048814=GO_REF:0000024, GO:0002250=GO_REF:0000019, GO:0032801=PMID:18544533, GO:0019048=GO_REF:0000037, GO:0019871=PMID:10642508, GO:0006622=PMID:17116753, GO:0043162=PMID:20086093} P46934 E3 ubiquitin-protein ligase NEDD4 protein 20120801 {GO:0005515=IPI, GO:0043130=IDA, GO:0004842=IDA, GO:0006513=IEA, GO:0019221=TAS, GO:0031698=IDA, GO:0031175=IEP, GO:0005622=IEA, GO:0031623=IDA, GO:0070534=ISS, GO:0034644=IMP, GO:0042787=IDA, GO:0010766=IDA, GO:0010768=IMP, GO:0070063=IPI, GO:0005938=IDA, GO:0070064=IMP, GO:0000785=IDA, GO:0050847=IDA, GO:0005794=IDA, GO:0019904=IPI, GO:0014068=IMP, GO:1901016=IDA, GO:0051592=TAS, GO:0042110=IEA, GO:0050807=IEA, GO:0042921=IDA, GO:0007041=IDA, GO:0030948=ISS, GO:0044111=IMP, GO:0045732=IDA, GO:0048471=IDA, GO:0005886=IMP, GO:0048514=IEA, GO:0000151=ISS, GO:0005634=IBA, GO:0005829=TAS, GO:0050815=ISS, GO:0050816=ISS, GO:0005737=IDA, GO:0007528=IEA, GO:0042391=IDA, GO:0034765=IDA, GO:0046824=IDA, GO:0019089=IMP, GO:0003197=IEA, GO:0003151=IEA, GO:0016327=TAS, GO:0048814=ISS, GO:0002250=IEA, GO:0032801=IDA, GO:0019048=IEA, GO:0019871=IDA, GO:0006622=IDA, GO:0043162=IMP} T cell activation, adaptive immune response, blood vessel morphogenesis, cellular response to UV, cytokine-mediated signaling pathway, development involved in symbiotic interaction, endocardial cushion development, glucocorticoid receptor signaling pathway, lysosomal transport, negative regulation of sodium ion transport, negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage, negative regulation of vascular endothelial growth factor receptor signaling pathway, neuromuscular junction development, neuron projection development, outflow tract morphogenesis, positive regulation of nucleocytoplasmic transport, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of protein catabolic process, progesterone receptor signaling pathway, protein K63-linked ubiquitination, protein monoubiquitination, protein targeting to lysosome, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, receptor catabolic process, receptor internalization, regulation of dendrite morphogenesis, regulation of ion transmembrane transport, regulation of membrane potential, regulation of potassium ion transmembrane transporter activity, regulation of synapse organization, response to calcium ion, transmission of virus, ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway, virus-host interaction Golgi apparatus, apicolateral plasma membrane, cell cortex, chromatin, cytoplasm, cytosol, intracellular, nucleus, perinuclear region of cytoplasm, plasma membrane, ubiquitin ligase complex RNA polymerase binding, beta-2 adrenergic receptor binding, phosphoserine binding, phosphothreonine binding, proline-rich region binding, protein binding, protein domain specific binding, sodium channel inhibitor activity, ubiquitin binding, ubiquitin-protein ligase activity Human NEDD4L BHF-UCL UniProtKB {GO:0005515=PMID:19664597, GO:0010467=Reactome:REACT_71, GO:0004842=Reactome:REACT_160256, GO:0006367=Reactome:REACT_12627, GO:2000810=GO_REF:0000019, GO:0009651=GO_REF:0000019, GO:0016567=PMID:11244092, GO:0006883=PMID:11244092, GO:0005634=GO_REF:0000033, GO:2001259=GO_REF:0000019, GO:0005829=Reactome:REACT_160256, GO:0005622=PMID:11244092, GO:0045807=PMID:11244092, GO:0030104=PMID:11244092, GO:0005737=GO_REF:0000033, GO:0034220=Reactome:REACT_25300, GO:0042787=GO_REF:0000033, GO:0010765=GO_REF:0000019, GO:0010766=GO_REF:0000019, GO:0010038=PMID:11244092, GO:0042391=PMID:17289006, GO:0034765=PMID:17289006, GO:0007179=Reactome:REACT_120850, GO:0006814=PMID:11244092, GO:0003085=GO_REF:0000019, GO:0030512=Reactome:REACT_120727, GO:0007588=PMID:11244092, GO:0042176=PMID:11244092, GO:0000122=Reactome:REACT_121111, GO:0055085=Reactome:REACT_15518, GO:0006351=Reactome:REACT_121061, GO:1901016=PMID:17289006, GO:0019048=GO_REF:0000037, GO:0019871=GO_REF:0000019, GO:0005654=Reactome:REACT_121357, GO:0043162=GO_REF:0000019, GO:0017080=PMID:11244092} Q96PU5 E3 ubiquitin-protein ligase NEDD4-like protein 20120801 {GO:0005515=IPI, GO:0010467=TAS, GO:0004842=TAS, GO:0006367=TAS, GO:2000810=IEA, GO:0009651=IEA, GO:0016567=NAS, GO:0006883=NAS, GO:0005634=IBA, GO:2001259=IEA, GO:0005829=TAS, GO:0005622=IC, GO:0045807=NAS, GO:0030104=NAS, GO:0005737=IBA, GO:0034220=TAS, GO:0042787=IBA, GO:0010765=IEA, GO:0010766=IEA, GO:0010038=IDA, GO:0042391=IDA, GO:0034765=IDA, GO:0007179=TAS, GO:0006814=NAS, GO:0003085=IEA, GO:0030512=TAS, GO:0007588=NAS, GO:0042176=NAS, GO:0000122=TAS, GO:0055085=TAS, GO:0006351=TAS, GO:1901016=IDA, GO:0019048=IEA, GO:0019871=IEA, GO:0005654=TAS, GO:0043162=IEA, GO:0017080=IDA} cellular sodium ion homeostasis, excretion, gene expression, ion transmembrane transport, negative regulation of sodium ion transport, negative regulation of systemic arterial blood pressure, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transforming growth factor beta receptor signaling pathway, positive regulation of cation channel activity, positive regulation of endocytosis, positive regulation of sodium ion transport, protein ubiquitination, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, regulation of ion transmembrane transport, regulation of membrane potential, regulation of potassium ion transmembrane transporter activity, regulation of protein catabolic process, regulation of tight junction assembly, response to metal ion, response to salt stress, sodium ion transport, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, transmembrane transport, ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway, virus-host interaction, water homeostasis cytoplasm, cytosol, intracellular, nucleoplasm, nucleus protein binding, sodium channel inhibitor activity, sodium channel regulator activity, ubiquitin-protein ligase activity Human NEDD8 MGI UniProtKB {GO:0006511=PMID:9353319, GO:0014070=GO_REF:0000019, GO:0008104=GO_REF:0000019, GO:0006357=GO_REF:0000019, GO:0045116=PMID:10500095, GO:0006508=PMID:9694792, GO:0005634=GO_REF:0000039, GO:0009653=PMID:9694792, GO:0006464=PMID:9694792, GO:0031625=PMID:15694336} Q15843 NEDD8 protein 20080902 {GO:0006511=TAS, GO:0014070=IEA, GO:0008104=IEA, GO:0006357=IEA, GO:0045116=IDA, GO:0006508=TAS, GO:0005634=IEA, GO:0009653=TAS, GO:0006464=TAS, GO:0031625=IPI} anatomical structure morphogenesis, cellular protein modification process, protein localization, protein neddylation, proteolysis, regulation of transcription from RNA polymerase II promoter, response to organic cyclic compound, ubiquitin-dependent protein catabolic process nucleus ubiquitin protein ligase binding Human NEDD9 PINC UniProtKB {GO:0005515=PMID:11827972, GO:0005794=GO_REF:0000039, GO:0005819=PMID:9584194, GO:0005634=GO_REF:0000039, GO:0030027=GO_REF:0000039, GO:0007165=PMID:8668148, GO:0005737=PMID:9584194, GO:0000922=GO_REF:0000019, GO:0007067=GO_REF:0000037, GO:0007229=PMID:11827972, GO:0007010=PMID:11827972, GO:0007155=GO_REF:0000037, GO:0005925=GO_REF:0000039, GO:0005938=GO_REF:0000039, GO:0051017=PMID:11827972, GO:0040008=GO_REF:0000037, GO:0051301=GO_REF:0000037} Q14511 Enhancer of filamentation 1 protein 20030904 {GO:0005515=IPI, GO:0005794=IEA, GO:0005819=TAS, GO:0005634=IEA, GO:0030027=IEA, GO:0007165=TAS, GO:0005737=TAS, GO:0000922=IEA, GO:0007067=IEA, GO:0007229=NAS, GO:0007010=NAS, GO:0007155=IEA, GO:0005925=IEA, GO:0005938=IEA, GO:0051017=NAS, GO:0040008=IEA, GO:0051301=IEA} actin filament bundle assembly, cell adhesion, cell division, cytoskeleton organization, integrin-mediated signaling pathway, mitosis, regulation of growth, signal transduction Golgi apparatus, cell cortex, cytoplasm, focal adhesion, lamellipodium, nucleus, spindle, spindle pole protein binding Human NEFH UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0030424=PMID:14662745, GO:0003674=GO_REF:0000015, GO:0008219=GO_REF:0000037, GO:0060052=GO_REF:0000019, GO:0005883=PMID:3138108, GO:0045110=GO_REF:0000019, GO:0000226=GO_REF:0000019, GO:0007399=GO_REF:0000029} P12036 Neurofilament heavy polypeptide protein 20050114 {GO:0005739=IEA, GO:0030424=TAS, GO:0003674=ND, GO:0008219=IEA, GO:0060052=IEA, GO:0005883=NAS, GO:0045110=IEA, GO:0000226=IEA, GO:0007399=NAS} cell death, intermediate filament bundle assembly, microtubule cytoskeleton organization, nervous system development, neurofilament cytoskeleton organization axon, mitochondrion, neurofilament molecular_function Human NEFL IntAct UniProtKB {GO:0005515=PMID:12837694, GO:0030424=PMID:14662745, GO:0008090=PMID:15857389, GO:0045109=PMID:17052987, GO:0005883=PMID:15857389, GO:0007268=Reactome:REACT_13685, GO:0008022=PMID:12226091, GO:0042802=PMID:12432080, GO:0005829=Reactome:REACT_20670, GO:0033596=PMID:12226091, GO:0005200=PMID:12432080, GO:0033693=PMID:15857389, GO:0019896=PMID:15857389, GO:0008089=PMID:15857389} P07196 Neurofilament light polypeptide protein 20130415 {GO:0005515=IPI, GO:0030424=IDA, GO:0008090=IMP, GO:0045109=IMP, GO:0005883=IDA, GO:0007268=TAS, GO:0008022=IPI, GO:0042802=IPI, GO:0005829=TAS, GO:0033596=IDA, GO:0005200=IDA, GO:0033693=IMP, GO:0019896=IMP, GO:0008089=IMP} anterograde axon cargo transport, axon transport of mitochondrion, intermediate filament organization, neurofilament bundle assembly, retrograde axon cargo transport, synaptic transmission TSC1-TSC2 complex, axon, cytosol, neurofilament identical protein binding, protein C-terminus binding, protein binding, structural constituent of cytoskeleton Human UniProtKB:Q13614 NEFM HPA UniProtKB {GO:0005882=GO_REF:0000038, GO:0005515=PMID:20195357, GO:0030424=PMID:14662745, GO:0060052=GO_REF:0000019, GO:0031594=GO_REF:0000019, GO:0005883=GO_REF:0000019, GO:0031133=GO_REF:0000019, GO:0000226=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0005198=GO_REF:0000002, GO:0045110=GO_REF:0000019, GO:0005200=PMID:3608989, GO:0008088=GO_REF:0000019} P07197 Neurofilament medium polypeptide protein 20100326 {GO:0005882=IEA, GO:0005515=IPI, GO:0030424=TAS, GO:0060052=IEA, GO:0031594=IEA, GO:0005883=IEA, GO:0031133=IEA, GO:0000226=IEA, GO:0005737=IDA, GO:0005198=IEA, GO:0045110=IEA, GO:0005200=TAS, GO:0008088=IEA} axon cargo transport, intermediate filament bundle assembly, microtubule cytoskeleton organization, neurofilament cytoskeleton organization, regulation of axon diameter axon, cytoplasm, intermediate filament, neurofilament, neuromuscular junction protein binding, structural constituent of cytoskeleton, structural molecule activity Human NEGR1 IntAct UniProtKB {GO:0005515=PMID:21982860, GO:0005886=GO_REF:0000039, GO:0031225=GO_REF:0000037, GO:0007155=GO_REF:0000037} Q7Z3B1 Neuronal growth regulator 1 protein 20130415 {GO:0005515=IPI, GO:0005886=IEA, GO:0031225=IEA, GO:0007155=IEA} cell adhesion anchored to membrane, plasma membrane protein binding Human UniProtKB:Q9P121 NEIL1 UniProtKB UniProtKB {GO:0003906=GO_REF:0000003, GO:0005815=GO_REF:0000039, GO:0005694=GO_REF:0000039, GO:0005634=PMID:17611195, GO:0008022=PMID:17611195, GO:0016799=GO_REF:0000002, GO:0016829=GO_REF:0000019, GO:0032074=PMID:17611195, GO:0003684=GO_REF:0000002, GO:0005737=PMID:17611195, GO:0019104=GO_REF:0000019, GO:0006281=GO_REF:0000019, GO:0016798=PMID:17611195, GO:0006284=PMID:17611195, GO:0008270=GO_REF:0000002, GO:0006289=GO_REF:0000002, GO:0006979=PMID:17611195} Q96FI4 Endonuclease 8-like 1 protein 20080605 {GO:0003906=IEA, GO:0005815=IEA, GO:0005694=IEA, GO:0005634=IDA, GO:0008022=IPI, GO:0016799=IEA, GO:0016829=IEA, GO:0032074=IDA, GO:0003684=IEA, GO:0005737=IDA, GO:0019104=IEA, GO:0006281=IEA, GO:0016798=IDA, GO:0006284=IDA, GO:0008270=IEA, GO:0006289=IEA, GO:0006979=IDA} DNA repair, base-excision repair, negative regulation of nuclease activity, nucleotide-excision repair, response to oxidative stress chromosome, cytoplasm, microtubule organizing center, nucleus DNA N-glycosylase activity, DNA-(apurinic or apyrimidinic site) lyase activity, damaged DNA binding, hydrolase activity, acting on glycosyl bonds, hydrolase activity, hydrolyzing N-glycosyl compounds, lyase activity, protein C-terminus binding, zinc ion binding Human NEIL2 UniProtKB UniProtKB {GO:0008017=GO_REF:0000019, GO:0003906=GO_REF:0000003, GO:0003684=GO_REF:0000002, GO:0005737=GO_REF:0000019, GO:0006284=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0005876=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0006289=GO_REF:0000002, GO:0016799=GO_REF:0000002} Q969S2 Endonuclease 8-like 2 protein 20130413 {GO:0008017=IEA, GO:0003906=IEA, GO:0003684=IEA, GO:0005737=IEA, GO:0006284=IEA, GO:0005634=IEA, GO:0005876=IEA, GO:0008270=IEA, GO:0006289=IEA, GO:0016799=IEA} base-excision repair, nucleotide-excision repair cytoplasm, nucleus, spindle microtubule DNA-(apurinic or apyrimidinic site) lyase activity, damaged DNA binding, hydrolase activity, hydrolyzing N-glycosyl compounds, microtubule binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 NEIL3 UniProtKB UniProtKB {GO:0003906=PMID:19170771, GO:0003684=GO_REF:0000002, GO:0019104=PMID:19121397, GO:0003690=GO_REF:0000024, GO:0003697=PMID:19170771, GO:0000405=GO_REF:0000024, GO:0006284=GO_REF:0000024, GO:0005634=PMID:12433996, GO:0008270=GO_REF:0000002, GO:0006289=GO_REF:0000002} Q8TAT5 Endonuclease 8-like 3 protein 20100312 {GO:0003906=IDA, GO:0003684=IEA, GO:0019104=IDA, GO:0003690=ISS, GO:0003697=IDA, GO:0000405=ISS, GO:0006284=ISS, GO:0005634=IDA, GO:0008270=IEA, GO:0006289=IEA} base-excision repair, nucleotide-excision repair nucleus DNA N-glycosylase activity, DNA-(apurinic or apyrimidinic site) lyase activity, bubble DNA binding, damaged DNA binding, double-stranded DNA binding, single-stranded DNA binding, zinc ion binding NOT Human NEK1 HPA UniProtKB {GO:0005515=PMID:14690447, GO:0005813=PMID:21399614, GO:0031965=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=PMID:15604234, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0006974=GO_REF:0000019, GO:0042384=PMID:21211617, GO:0005737=PMID:15604234, GO:0007067=GO_REF:0000037, GO:0004672=PMID:15604234, GO:0004674=GO_REF:0000037, GO:0010212=GO_REF:0000019, GO:0004713=GO_REF:0000037, GO:0000242=PMID:21211617, GO:0051301=GO_REF:0000037} Q96PY6 Serine/threonine-protein kinase Nek1 protein 20110516 {GO:0005515=IPI, GO:0005813=IDA, GO:0031965=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0005524=IEA, GO:0046872=IEA, GO:0006974=IEA, GO:0042384=IMP, GO:0005737=IDA, GO:0007067=IEA, GO:0004672=IDA, GO:0004674=IEA, GO:0010212=IEA, GO:0004713=IEA, GO:0000242=IDA, GO:0051301=IEA} cell division, cilium assembly, mitosis, response to DNA damage stimulus, response to ionizing radiation centrosome, cytoplasm, nuclear membrane, nucleolus, nucleus, pericentriolar material ATP binding, metal ion binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, protein tyrosine kinase activity Human NEK10 InterPro UniProtKB {GO:0004674=GO_REF:0000037, GO:0004713=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q8N774 Serine/threonine-protein kinase Nek10 protein 20130413 {GO:0004674=IEA, GO:0004713=IEA, GO:0005524=IEA, GO:0046872=IEA} ATP binding, metal ion binding, protein serine/threonine kinase activity, protein tyrosine kinase activity Human InterPro:IPR000719 NEK11 HPA UniProtKB {GO:0004674=PMID:19734889, GO:0031573=PMID:15161910, GO:0031572=PMID:19734889, GO:0005730=GO_REF:0000052, GO:0006468=PMID:19734889, GO:0005634=GO_REF:0000052, GO:0005524=PMID:15161910, GO:0007243=PMID:15161910, GO:0046872=GO_REF:0000037, GO:0016772=GO_REF:0000002} Q8NG66 Serine/threonine-protein kinase Nek11 protein 20090616 {GO:0004674=IDA, GO:0031573=IDA, GO:0031572=IMP, GO:0005730=IDA, GO:0006468=IDA, GO:0005634=IDA, GO:0005524=IDA, GO:0007243=IDA, GO:0046872=IEA, GO:0016772=IEA} G2 DNA damage checkpoint, intra-S DNA damage checkpoint, intracellular protein kinase cascade, protein phosphorylation nucleolus, nucleus ATP binding, metal ion binding, protein serine/threonine kinase activity, transferase activity, transferring phosphorus-containing groups NOT Human NEK2 IntAct UniProtKB {GO:0005515=PMID:16648845, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_15470, GO:0046777=PMID:17626005, GO:0007059=PMID:14978040, GO:0000086=Reactome:REACT_2203, GO:0090307=GO_REF:0000019, GO:0007088=PMID:9430639, GO:0005813=PMID:21399614, GO:0000794=GO_REF:0000019, GO:0051988=PMID:18297113, GO:0019903=PMID:10880350, GO:0005874=GO_REF:0000037, GO:0001824=GO_REF:0000019, GO:0046602=PMID:16280549, GO:0005730=GO_REF:0000039, GO:0030496=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0051225=PMID:16280549, GO:0043392=GO_REF:0000019, GO:0043234=PMID:10880350, GO:0007067=PMID:9430639, GO:0000922=GO_REF:0000039, GO:0000070=GO_REF:0000019, GO:0007126=GO_REF:0000037, GO:0004672=PMID:18086858, GO:0004674=PMID:16280549, GO:0051299=PMID:18086858, GO:0000777=GO_REF:0000039, GO:0000776=PMID:14978040, GO:0006468=PMID:21076410, GO:0000278=Reactome:REACT_152, GO:0051301=GO_REF:0000037} P51955 Serine/threonine-protein kinase Nek2 protein 20130415 {GO:0005515=IPI, GO:0046872=IEA, GO:0005829=TAS, GO:0046777=IDA, GO:0007059=IDA, GO:0000086=TAS, GO:0090307=IEA, GO:0007088=TAS, GO:0005813=IDA, GO:0000794=IEA, GO:0051988=IMP, GO:0019903=IPI, GO:0005874=IEA, GO:0001824=IEA, GO:0046602=TAS, GO:0005730=IEA, GO:0030496=IEA, GO:0005524=IEA, GO:0051225=TAS, GO:0043392=IEA, GO:0043234=IMP, GO:0007067=TAS, GO:0000922=IEA, GO:0000070=IEA, GO:0007126=IEA, GO:0004672=IDA, GO:0004674=TAS, GO:0051299=IDA, GO:0000777=IEA, GO:0000776=IDA, GO:0006468=IDA, GO:0000278=TAS, GO:0051301=IEA} G2/M transition of mitotic cell cycle, blastocyst development, cell division, centrosome separation, chromosome segregation, meiosis, mitosis, mitotic cell cycle, mitotic sister chromatid segregation, negative regulation of DNA binding, protein autophosphorylation, protein phosphorylation, regulation of attachment of spindle microtubules to kinetochore, regulation of mitosis, regulation of mitotic centrosome separation, spindle assembly, spindle assembly involved in mitosis centrosome, condensed chromosome kinetochore, condensed nuclear chromosome, cytosol, kinetochore, microtubule, midbody, nucleolus, protein complex, spindle pole ATP binding, metal ion binding, protein binding, protein kinase activity, protein phosphatase binding, protein serine/threonine kinase activity Human UniProtKB:Q6GQ04 NEK3 UniProtKB UniProtKB {GO:0005515=PMID:15618286, GO:0030424=GO_REF:0000039, GO:0007049=GO_REF:0000029, GO:0007067=PMID:7522034, GO:0005737=GO_REF:0000039, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000002, GO:0006468=GO_REF:0000024, GO:0005634=PMID:7522034, GO:0005524=GO_REF:0000038, GO:0046872=GO_REF:0000037, GO:0051301=GO_REF:0000037} Q6ZN64 cDNA FLJ16392 fis, clone TRACH2020048, moderately similar to Mus musculus serine/threonine-protein kinase NEK3 (Nek3) mRNA protein 20130413 {GO:0005515=IPI, GO:0030424=IEA, GO:0007049=NAS, GO:0007067=NAS, GO:0005737=IEA, GO:0004672=IEA, GO:0004674=IEA, GO:0006468=ISS, GO:0005634=NAS, GO:0005524=IEA, GO:0046872=IEA, GO:0051301=IEA} cell cycle, cell division, mitosis, protein phosphorylation axon, cytoplasm, nucleus ATP binding, metal ion binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB-KW:KW-0067 NEK4 HPA UniProtKB {GO:0007067=GO_REF:0000037, GO:0004674=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0006468=PMID:8208544, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0051301=GO_REF:0000037} P51957 Serine/threonine-protein kinase Nek4 protein 20090616 {GO:0007067=IEA, GO:0004674=IEA, GO:0005730=IDA, GO:0006468=TAS, GO:0005634=IDA, GO:0005524=IEA, GO:0046872=IEA, GO:0051301=IEA} cell division, mitosis, protein phosphorylation nucleolus, nucleus ATP binding, metal ion binding, protein serine/threonine kinase activity NOT Human NEK6 GOC UniProtKB {GO:0007077=Reactome:REACT_160255, GO:0031572=PMID:18728393, GO:0005634=PMID:12054534, GO:0005829=Reactome:REACT_160202, GO:0000910=PMID:21200151, GO:0005737=PMID:12054534, GO:0007059=PMID:14563848, GO:0046777=PMID:20873783, GO:0000088=Reactome:REACT_765, GO:0018105=PMID:19001501, GO:0000087=Reactome:REACT_910, GO:0004871=PMID:12761501, GO:0043123=PMID:12761501, GO:2000772=PMID:21200151, GO:0000287=PMID:14563848, GO:0005815=GO_REF:0000039, GO:0019901=PMID:19001501, GO:0005874=GO_REF:0000037, GO:0006915=GO_REF:0000037, GO:0005524=PMID:14563848, GO:0051225=PMID:21200151, GO:0007165=PMID:12761501, GO:0007346=PMID:16280549, GO:0000922=GO_REF:0000039, GO:0004672=GO_REF:0000002, GO:0016607=GO_REF:0000039, GO:0004674=PMID:20873783, GO:0006468=PMID:12840024, GO:0030071=PMID:14563848, GO:0019894=PMID:19001501, GO:0000278=Reactome:REACT_152} Q9HC98 Serine/threonine-protein kinase Nek6 protein 20130413 {GO:0007077=TAS, GO:0031572=IMP, GO:0005634=IDA, GO:0005829=TAS, GO:0000910=TAS, GO:0005737=IDA, GO:0007059=IDA, GO:0046777=IDA, GO:0000088=TAS, GO:0018105=IDA, GO:0000087=TAS, GO:0004871=IMP, GO:0043123=IMP, GO:2000772=TAS, GO:0000287=IDA, GO:0005815=IEA, GO:0019901=IPI, GO:0005874=IEA, GO:0006915=IEA, GO:0005524=IDA, GO:0051225=TAS, GO:0007165=IMP, GO:0007346=TAS, GO:0000922=IEA, GO:0004672=IEA, GO:0016607=IEA, GO:0004674=IDA, GO:0006468=IDA, GO:0030071=IDA, GO:0019894=IPI, GO:0000278=TAS} G2 DNA damage checkpoint, M phase of mitotic cell cycle, apoptotic process, chromosome segregation, cytokinesis, mitotic cell cycle, mitotic nuclear envelope disassembly, mitotic prophase, peptidyl-serine phosphorylation, positive regulation of I-kappaB kinase/NF-kappaB cascade, protein autophosphorylation, protein phosphorylation, regulation of cellular senescence, regulation of mitotic cell cycle, regulation of mitotic metaphase/anaphase transition, signal transduction, spindle assembly cytoplasm, cytosol, microtubule, microtubule organizing center, nuclear speck, nucleus, spindle pole ATP binding, kinesin binding, magnesium ion binding, protein kinase activity, protein kinase binding, protein serine/threonine kinase activity, signal transducer activity Human NEK7 UniProtKB UniProtKB {GO:0007346=PMID:17727698, GO:0000910=PMID:17727698, GO:0005737=GO_REF:0000039, GO:0000922=GO_REF:0000039, GO:0005815=GO_REF:0000039, GO:0004674=GO_REF:0000024, GO:0005874=GO_REF:0000037, GO:0006468=PMID:12840024, GO:0005634=GO_REF:0000039, GO:0051225=PMID:17727698, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q8TDX7 Serine/threonine-protein kinase Nek7 protein 20110904 {GO:0007346=TAS, GO:0000910=TAS, GO:0005737=IEA, GO:0000922=IEA, GO:0005815=IEA, GO:0004674=ISS, GO:0005874=IEA, GO:0006468=IDA, GO:0005634=IEA, GO:0051225=TAS, GO:0005524=IEA, GO:0046872=IEA} cytokinesis, protein phosphorylation, regulation of mitotic cell cycle, spindle assembly cytoplasm, microtubule, microtubule organizing center, nucleus, spindle pole ATP binding, metal ion binding, protein serine/threonine kinase activity Human UniProtKB:D3ZBE5 NEK8 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000037, GO:0072372=GO_REF:0000024, GO:0005856=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q86SG6 Serine/threonine-protein kinase Nek8 protein 20110628 {GO:0005737=IEA, GO:0004672=IEA, GO:0004674=IEA, GO:0072372=ISS, GO:0005856=IEA, GO:0005524=IEA, GO:0046872=IEA} cytoplasm, cytoskeleton, primary cilium ATP binding, metal ion binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB:Q91ZR4 NEK9 HPA UniProtKB {GO:0007077=Reactome:REACT_160255, GO:0005515=PMID:20562859, GO:0019901=PMID:19001501, GO:0005634=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_160237, GO:0005739=GO_REF:0000052, GO:0000088=Reactome:REACT_765, GO:0004674=Reactome:REACT_160129, GO:0000087=Reactome:REACT_910, GO:0000278=Reactome:REACT_152, GO:0051301=GO_REF:0000037} Q8TD19 Serine/threonine-protein kinase Nek9 protein 20080205 {GO:0007077=TAS, GO:0005515=IPI, GO:0019901=IPI, GO:0005634=IEA, GO:0005524=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0005739=IDA, GO:0000088=TAS, GO:0004674=EXP, GO:0000087=TAS, GO:0000278=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, cell division, mitotic cell cycle, mitotic nuclear envelope disassembly, mitotic prophase cytosol, mitochondrion, nucleus ATP binding, metal ion binding, protein binding, protein kinase binding, protein serine/threonine kinase activity Human NELL1 PINC UniProtKB {GO:0010468=PMID:21723284, GO:0005515=PMID:21723284, GO:0048471=PMID:21723284, GO:0030501=PMID:21723284, GO:0033689=PMID:21723284, GO:0005509=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0005635=PMID:21723284, GO:0030154=GO_REF:0000037, GO:0007399=PMID:8975702, GO:0045669=PMID:21723284, GO:2000599=PMID:21723284, GO:0005737=PMID:21723284} Q92832 Protein kinase C-binding protein NELL1 protein 20030904 {GO:0010468=IDA, GO:0005515=IPI, GO:0048471=IDA, GO:0030501=IDA, GO:0033689=IDA, GO:0005509=IEA, GO:0005576=IEA, GO:0005635=IDA, GO:0030154=IEA, GO:0007399=TAS, GO:0045669=IDA, GO:2000599=IDA, GO:0005737=IDA} cell differentiation, negative regulation of cyclin catabolic process, negative regulation of osteoblast proliferation, nervous system development, positive regulation of bone mineralization, positive regulation of osteoblast differentiation, regulation of gene expression cytoplasm, extracellular region, nuclear envelope, perinuclear region of cytoplasm calcium ion binding, protein binding Human NELL2 IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0005198=GO_REF:0000029, GO:0005509=GO_REF:0000029, GO:0005576=GO_REF:0000029, GO:0007155=GO_REF:0000029} Q99435 Protein kinase C-binding protein NELL2 protein 20130415 {GO:0005515=IPI, GO:0005198=NAS, GO:0005509=NAS, GO:0005576=NAS, GO:0007155=NAS} cell adhesion extracellular region calcium ion binding, protein binding, structural molecule activity Human UniProtKB:Q5VTD9 NEMF HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0051168=PMID:16103875} O60524 Nuclear export mediator factor NEMF protein 20101115 {GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0051168=IMP} nuclear export cytoplasm, nucleolus, nucleus Human NENF UniProtKB UniProtKB {GO:0043410=GO_REF:0000019, GO:0005615=GO_REF:0000039, GO:0008083=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0020037=GO_REF:0000002} Q9UMX5 Neudesin protein 20130413 {GO:0043410=IEA, GO:0005615=IEA, GO:0008083=IEA, GO:0046872=IEA, GO:0020037=IEA} positive regulation of MAPK cascade extracellular space growth factor activity, heme binding, metal ion binding Human UniProtKB-SubCell:SL-0112 NEO1 Reactome UniProtKB {GO:0042692=Reactome:REACT_21303, GO:0006355=GO_REF:0000019, GO:0051149=Reactome:REACT_21402, GO:0045296=GO_REF:0000019, GO:0005886=Reactome:REACT_22235, GO:0007411=Reactome:REACT_18266, GO:0005887=PMID:9169140, GO:0007520=GO_REF:0000019, GO:0004872=GO_REF:0000019, GO:0016021=GO_REF:0000002, GO:0007155=GO_REF:0000037, GO:0055072=PMID:16075058} Q92859 Neogenin protein 20090519 {GO:0042692=TAS, GO:0006355=IEA, GO:0051149=TAS, GO:0045296=IEA, GO:0005886=TAS, GO:0007411=TAS, GO:0005887=TAS, GO:0007520=IEA, GO:0004872=IEA, GO:0016021=IEA, GO:0007155=IEA, GO:0055072=IGI} axon guidance, cell adhesion, iron ion homeostasis, muscle cell differentiation, myoblast fusion, positive regulation of muscle cell differentiation, regulation of transcription, DNA-dependent integral to membrane, integral to plasma membrane, plasma membrane cadherin binding, receptor activity Human NES HPA UniProtKB {GO:0032091=PMID:21185309, GO:0005882=PMID:9917366, GO:0043066=GO_REF:0000024, GO:2000179=GO_REF:0000024, GO:0072089=PMID:19384922, GO:0048858=GO_REF:0000019, GO:0007417=PMID:9917366, GO:0019215=GO_REF:0000024, GO:0003674=GO_REF:0000015, GO:0030844=GO_REF:0000024, GO:0005737=PMID:19384922, GO:0031076=GO_REF:0000024, GO:0005198=GO_REF:0000002, GO:0007420=GO_REF:0000024, GO:0000086=PMID:19384922, GO:0045111=GO_REF:0000052} P48681 Nestin protein 20111111 {GO:0032091=IDA, GO:0005882=NAS, GO:0043066=ISS, GO:2000179=ISS, GO:0072089=IMP, GO:0048858=IEA, GO:0007417=NAS, GO:0019215=ISS, GO:0003674=ND, GO:0030844=ISS, GO:0005737=IDA, GO:0031076=ISS, GO:0005198=IEA, GO:0007420=ISS, GO:0000086=IDA, GO:0045111=IDA} G2/M transition of mitotic cell cycle, brain development, cell projection morphogenesis, central nervous system development, embryonic camera-type eye development, negative regulation of apoptotic process, negative regulation of protein binding, positive regulation of intermediate filament depolymerization, positive regulation of neural precursor cell proliferation, stem cell proliferation cytoplasm, intermediate filament, intermediate filament cytoskeleton intermediate filament binding, molecular_function, structural molecule activity Human NET1 Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0070301=PMID:21373644, GO:0043065=PMID:21373644, GO:0007264=Reactome:REACT_11044, GO:0035023=GO_REF:0000002, GO:0006915=Reactome:REACT_13638, GO:0005634=GO_REF:0000039, GO:0097190=Reactome:REACT_13720, GO:0001558=PMID:8649828, GO:0071479=PMID:21373644, GO:0005829=Reactome:REACT_19216, GO:0035556=GO_REF:0000002, GO:0005085=PMID:8649828, GO:0005622=GO_REF:0000002, GO:0007165=PMID:8649828, GO:0005543=GO_REF:0000002, GO:0032321=PMID:21373644, GO:0005089=GO_REF:0000002} Q7Z628 Neuroepithelial cell-transforming gene 1 protein protein 20130301 {GO:0051056=TAS, GO:0048011=TAS, GO:0070301=IDA, GO:0043065=IDA, GO:0007264=TAS, GO:0035023=IEA, GO:0006915=TAS, GO:0005634=IEA, GO:0097190=TAS, GO:0001558=NAS, GO:0071479=IDA, GO:0005829=TAS, GO:0035556=IEA, GO:0005085=TAS, GO:0005622=IEA, GO:0007165=TAS, GO:0005543=IEA, GO:0032321=IMP, GO:0005089=IEA} apoptotic process, apoptotic signaling pathway, cellular response to hydrogen peroxide, cellular response to ionizing radiation, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, positive regulation of Rho GTPase activity, positive regulation of apoptotic process, regulation of Rho protein signal transduction, regulation of cell growth, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular, nucleus Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, phospholipid binding Human NETO2 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8NC67 Neuropilin and tolloid-like protein 2 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 NEU1 HPA UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0030054=GO_REF:0000052, GO:0005886=GO_REF:0000039, GO:0006687=Reactome:REACT_116105, GO:0004308=PMID:8985184, GO:0044281=Reactome:REACT_111217, GO:0005765=GO_REF:0000039, GO:0005764=PMID:8985184, GO:0043231=GO_REF:0000052, GO:0052794=GO_REF:0000003, GO:0052796=GO_REF:0000003, GO:0052795=GO_REF:0000003, GO:0016023=GO_REF:0000039, GO:0043202=Reactome:REACT_116118} Q99519 Sialidase-1 protein 20110516 {GO:0006665=TAS, GO:0030054=IDA, GO:0005886=IEA, GO:0006687=TAS, GO:0004308=TAS, GO:0044281=TAS, GO:0005765=IEA, GO:0005764=TAS, GO:0043231=IDA, GO:0052794=IEA, GO:0052796=IEA, GO:0052795=IEA, GO:0016023=IEA, GO:0043202=TAS} glycosphingolipid metabolic process, small molecule metabolic process, sphingolipid metabolic process cell junction, cytoplasmic membrane-bounded vesicle, intracellular membrane-bounded organelle, lysosomal lumen, lysosomal membrane, lysosome, plasma membrane exo-alpha-(2->3)-sialidase activity, exo-alpha-(2->6)-sialidase activity, exo-alpha-(2->8)-sialidase activity, exo-alpha-sialidase activity Human NEU3 Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0005886=Reactome:REACT_115699, GO:0006687=Reactome:REACT_116105, GO:0005975=PMID:12730204, GO:0006689=PMID:10405317, GO:0004308=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0003824=PMID:10405317, GO:0052794=GO_REF:0000003, GO:0005887=PMID:10405317, GO:0052796=GO_REF:0000003, GO:0052795=GO_REF:0000003, GO:0016997=PMID:12730204} Q9UQ49 Sialidase-3 protein 20130301 {GO:0006665=TAS, GO:0005886=TAS, GO:0006687=TAS, GO:0005975=IDA, GO:0006689=TAS, GO:0004308=IEA, GO:0044281=TAS, GO:0003824=TAS, GO:0052794=IEA, GO:0005887=TAS, GO:0052796=IEA, GO:0052795=IEA, GO:0016997=IDA} carbohydrate metabolic process, ganglioside catabolic process, glycosphingolipid metabolic process, small molecule metabolic process, sphingolipid metabolic process integral to plasma membrane, plasma membrane alpha-sialidase activity, catalytic activity, exo-alpha-(2->3)-sialidase activity, exo-alpha-(2->6)-sialidase activity, exo-alpha-(2->8)-sialidase activity, exo-alpha-sialidase activity Human NEU4 IntAct UniProtKB {GO:0005515=PMID:19447967, GO:0006665=Reactome:REACT_19323, GO:0052794=GO_REF:0000003, GO:0005739=GO_REF:0000019, GO:0006687=Reactome:REACT_116105, GO:0052796=GO_REF:0000003, GO:0019866=PMID:14962670, GO:0052795=GO_REF:0000003, GO:0004308=PMID:14962670, GO:0044281=Reactome:REACT_111217, GO:0005764=PMID:14962670, GO:0043202=Reactome:REACT_116118} Q8WWR8 Sialidase-4 protein 20130415 {GO:0005515=IPI, GO:0006665=TAS, GO:0052794=IEA, GO:0005739=IEA, GO:0006687=TAS, GO:0052796=IEA, GO:0019866=IDA, GO:0052795=IEA, GO:0004308=IDA, GO:0044281=TAS, GO:0005764=IDA, GO:0043202=TAS} glycosphingolipid metabolic process, small molecule metabolic process, sphingolipid metabolic process lysosomal lumen, lysosome, mitochondrion, organelle inner membrane exo-alpha-(2->3)-sialidase activity, exo-alpha-(2->6)-sialidase activity, exo-alpha-(2->8)-sialidase activity, exo-alpha-sialidase activity, protein binding Human UniProtKB:Q99750 NEURL PINC UniProtKB {GO:0048471=GO_REF:0000039, GO:0016567=GO_REF:0000041, GO:0005886=GO_REF:0000039, GO:0016874=GO_REF:0000037, GO:0007288=GO_REF:0000019, GO:0030317=GO_REF:0000019, GO:0007399=PMID:9519875, GO:0009605=GO_REF:0000019, GO:0007219=GO_REF:0000037, GO:0007595=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0007519=GO_REF:0000019, GO:0008270=GO_REF:0000002} O76050 Neuralized-like protein 1A protein 20030904 {GO:0048471=IEA, GO:0016567=IEA, GO:0005886=IEA, GO:0016874=IEA, GO:0007288=IEA, GO:0030317=IEA, GO:0007399=TAS, GO:0009605=IEA, GO:0007219=IEA, GO:0007595=IEA, GO:0007420=IEA, GO:0007519=IEA, GO:0008270=IEA} Notch signaling pathway, brain development, lactation, nervous system development, protein ubiquitination, response to external stimulus, skeletal muscle tissue development, sperm axoneme assembly, sperm motility perinuclear region of cytoplasm, plasma membrane ligase activity, zinc ion binding Human NEURL1B UniPathway UniProtKB {GO:0005737=GO_REF:0000039, GO:0016567=GO_REF:0000041, GO:0007219=GO_REF:0000037, GO:0016874=GO_REF:0000037, GO:0008270=GO_REF:0000002} A8MQ27 E3 ubiquitin-protein ligase NEURL1B protein 20130413 {GO:0005737=IEA, GO:0016567=IEA, GO:0007219=IEA, GO:0016874=IEA, GO:0008270=IEA} Notch signaling pathway, protein ubiquitination cytoplasm ligase activity, zinc ion binding Human UniPathway:UPA00143 NEURL2 UniPathway UniProtKB {GO:0035556=GO_REF:0000002, GO:0016567=GO_REF:0000041, GO:0030891=GO_REF:0000019, GO:0045214=GO_REF:0000019, GO:0005927=GO_REF:0000019} Q9BR09 Neuralized-like protein 2 protein 20130413 {GO:0035556=IEA, GO:0016567=IEA, GO:0030891=IEA, GO:0045214=IEA, GO:0005927=IEA} intracellular signal transduction, protein ubiquitination, sarcomere organization VCB complex, muscle tendon junction Human UniPathway:UPA00143 NEURL4 UniProtKB UniProtKB {GO:0005814=GO_REF:0000039} Q96JN8 Neuralized-like protein 4 protein 20130413 {GO:0005814=IEA} centriole Human UniProtKB-SubCell:SL-0046 NEUROD1 BHF-UCL UniProtKB {GO:0071156=GO_REF:0000024, GO:0005515=PMID:14752053, GO:2000679=PMID:19619559, GO:0003700=PMID:10545951, GO:0007263=PMID:17941991, GO:0060730=GO_REF:0000024, GO:0045597=GO_REF:0000024, GO:0005634=PMID:10545951, GO:0009952=GO_REF:0000019, GO:0003326=GO_REF:0000019, GO:0051091=PMID:14752053, GO:0005737=GO_REF:0000039, GO:0003690=GO_REF:0000019, GO:0045944=PMID:10545951, GO:0003329=GO_REF:0000019, GO:0071333=GO_REF:0000019, GO:0022008=PMID:8786144, GO:0001102=PMID:19619559, GO:0021542=GO_REF:0000024, GO:0001105=PMID:19619559, GO:0043066=PMID:9308961, GO:0048839=GO_REF:0000024, GO:0043065=GO_REF:0000024, GO:0046982=PMID:10545951, GO:0023019=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0003713=PMID:14752053, GO:0070888=PMID:14752053, GO:0021549=GO_REF:0000024, GO:0042593=PMID:9308961, GO:0035883=GO_REF:0000024, GO:0035881=GO_REF:0000024, GO:0046426=GO_REF:0000019, GO:0048562=PMID:9308961, GO:0009749=PMID:10545951, GO:0006913=GO_REF:0000019, GO:0043565=PMID:10545951, GO:0050796=PMID:10545951, GO:0045666=GO_REF:0000024, GO:0031018=PMID:9308961, GO:0003682=GO_REF:0000024, GO:0005654=Reactome:REACT_13647, GO:0045893=GO_REF:0000024, GO:0030073=PMID:17941991, GO:0008134=PMID:16321656} Q13562 Neurogenic differentiation factor 1 protein 20110920 {GO:0071156=ISS, GO:0005515=IPI, GO:2000679=IDA, GO:0003700=IDA, GO:0007263=IDA, GO:0060730=ISS, GO:0045597=ISS, GO:0005634=IC, GO:0009952=IEA, GO:0003326=IEA, GO:0051091=IDA, GO:0005737=IEA, GO:0003690=IEA, GO:0045944=IDA, GO:0003329=IEA, GO:0071333=IEA, GO:0022008=TAS, GO:0001102=IPI, GO:0021542=ISS, GO:0001105=IDA, GO:0043066=ISS, GO:0048839=ISS, GO:0043065=ISS, GO:0046982=IPI, GO:0023019=IEA, GO:0042493=IEA, GO:0003713=IDA, GO:0070888=IDA, GO:0021549=ISS, GO:0042593=ISS, GO:0035883=ISS, GO:0035881=ISS, GO:0046426=IEA, GO:0048562=ISS, GO:0009749=IMP, GO:0006913=IEA, GO:0043565=IDA, GO:0050796=IC, GO:0045666=ISS, GO:0031018=ISS, GO:0003682=ISS, GO:0005654=TAS, GO:0045893=ISS, GO:0030073=IDA, GO:0008134=IPI} amacrine cell differentiation, anterior/posterior pattern specification, cellular response to glucose stimulus, cerebellum development, dentate gyrus development, embryonic organ morphogenesis, endocrine pancreas development, enteroendocrine cell differentiation, glucose homeostasis, inner ear development, insulin secretion, negative regulation of JAK-STAT cascade, negative regulation of apoptotic process, neurogenesis, nitric oxide mediated signal transduction, nucleocytoplasmic transport, pancreatic A cell fate commitment, pancreatic PP cell fate commitment, positive regulation of apoptotic process, positive regulation of cell differentiation, positive regulation of neuron differentiation, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription regulatory region DNA binding, positive regulation of transcription, DNA-dependent, regulation of cell cycle arrest, regulation of insulin secretion, regulation of intestinal epithelial structure maintenance, response to drug, response to glucose stimulus, signal transduction involved in regulation of gene expression cytoplasm, nucleoplasm, nucleus E-box binding, RNA polymerase II activating transcription factor binding, RNA polymerase II transcription coactivator activity, chromatin binding, double-stranded DNA binding, protein binding, protein heterodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, transcription factor binding Human NEUROD2 PINC UniProtKB {GO:0008306=GO_REF:0000019, GO:0090129=GO_REF:0000024, GO:0003700=PMID:8816493, GO:0016567=GO_REF:0000024, GO:0006357=PMID:8816493, GO:0046982=GO_REF:0000024, GO:0021695=GO_REF:0000024, GO:0003714=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0070888=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0007399=PMID:8816493, GO:0050850=GO_REF:0000024, GO:0051091=GO_REF:0000024, GO:0071257=GO_REF:0000024, GO:0031915=GO_REF:0000024, GO:0048666=GO_REF:0000019, GO:0045666=GO_REF:0000024, GO:0071277=GO_REF:0000024, GO:2000297=GO_REF:0000024, GO:0001662=GO_REF:0000019} Q15784 Neurogenic differentiation factor 2 protein 20030904 {GO:0008306=IEA, GO:0090129=ISS, GO:0003700=TAS, GO:0016567=ISS, GO:0006357=TAS, GO:0046982=ISS, GO:0021695=ISS, GO:0003714=ISS, GO:0005634=ISS, GO:0070888=ISS, GO:0006351=IEA, GO:0007399=TAS, GO:0050850=ISS, GO:0051091=ISS, GO:0071257=ISS, GO:0031915=ISS, GO:0048666=IEA, GO:0045666=ISS, GO:0071277=ISS, GO:2000297=ISS, GO:0001662=IEA} associative learning, behavioral fear response, cellular response to calcium ion, cellular response to electrical stimulus, cerebellar cortex development, negative regulation of synapse maturation, nervous system development, neuron development, positive regulation of calcium-mediated signaling, positive regulation of neuron differentiation, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of synapse maturation, positive regulation of synaptic plasticity, protein ubiquitination, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus E-box binding, protein heterodimerization activity, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human NEUROD4 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0045597=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0035881=GO_REF:0000024, GO:0007405=GO_REF:0000019, GO:0045165=GO_REF:0000019, GO:0007219=GO_REF:0000019, GO:0048666=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0010001=GO_REF:0000019, GO:0001764=GO_REF:0000019} Q9HD90 Neurogenic differentiation factor 4 protein 20110615 {GO:0006355=IEA, GO:0045597=ISS, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0035881=ISS, GO:0007405=IEA, GO:0045165=IEA, GO:0007219=IEA, GO:0048666=IEA, GO:0046983=IEA, GO:0010001=IEA, GO:0001764=IEA} Notch signaling pathway, amacrine cell differentiation, cell fate commitment, glial cell differentiation, neuroblast proliferation, neuron development, neuron migration, positive regulation of cell differentiation, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, protein dimerization activity Human UniProtKB:O09105 NEUROD6 UniProtKB UniProtKB {GO:0021542=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96NK8 Neurogenic differentiation factor 6 protein 20130413 {GO:0021542=IEA, GO:0006355=IEA, GO:0046983=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0030154=IEA, GO:0006351=IEA} cell differentiation, dentate gyrus development, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, protein dimerization activity Human UniProtKB-SubCell:SL-0191 NEUROG1 PINC UniProtKB {GO:0003700=PMID:8816493, GO:0042472=GO_REF:0000019, GO:0006357=PMID:8816493, GO:0031536=GO_REF:0000019, GO:0070888=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0000989=GO_REF:0000024, GO:0007399=PMID:8816493, GO:0051091=GO_REF:0000024, GO:0045165=GO_REF:0000019, GO:0045666=GO_REF:0000024, GO:0045944=GO_REF:0000024, GO:0003682=GO_REF:0000024, GO:0030182=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0043204=GO_REF:0000019} Q92886 Neurogenin-1 protein 20030904 {GO:0003700=TAS, GO:0042472=IEA, GO:0006357=TAS, GO:0031536=IEA, GO:0070888=ISS, GO:0005634=IEA, GO:0003677=ISS, GO:0006351=IEA, GO:0000989=ISS, GO:0007399=TAS, GO:0051091=ISS, GO:0045165=IEA, GO:0045666=ISS, GO:0045944=ISS, GO:0003682=ISS, GO:0030182=IEA, GO:0046983=IEA, GO:0043204=IEA} cell fate commitment, inner ear morphogenesis, nervous system development, neuron differentiation, positive regulation of exit from mitosis, positive regulation of neuron differentiation, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus, perikaryon DNA binding, E-box binding, chromatin binding, protein dimerization activity, sequence-specific DNA binding transcription factor activity, transcription factor binding transcription factor activity Human NEUROG2 UniProtKB UniProtKB {GO:0021954=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0070888=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000019, GO:0051091=GO_REF:0000024, GO:0045165=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0045666=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0030900=GO_REF:0000019, GO:0001764=GO_REF:0000019} Q9H2A3 Neurogenin-2 protein 20110520 {GO:0021954=IEA, GO:0005634=IEA, GO:0070888=ISS, GO:0006351=IEA, GO:0043565=IEA, GO:0051091=ISS, GO:0045165=IEA, GO:0007411=IEA, GO:0045666=IEA, GO:0045944=IEA, GO:0046983=IEA, GO:0030900=IEA, GO:0001764=IEA} axon guidance, cell fate commitment, central nervous system neuron development, forebrain development, neuron migration, positive regulation of neuron differentiation, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus E-box binding, protein dimerization activity, sequence-specific DNA binding Human UniProtKB:P70447 NEXN UniProtKB UniProtKB {GO:0030334=PMID:15823560, GO:0030018=GO_REF:0000024, GO:0051015=PMID:15823560, GO:0051493=PMID:15823560, GO:0008307=PMID:19881492, GO:0005856=GO_REF:0000039, GO:0005924=GO_REF:0000019} Q0ZGT2 Nexilin protein 20100225 {GO:0030334=IDA, GO:0030018=ISS, GO:0051015=IDA, GO:0051493=IEP, GO:0008307=IMP, GO:0005856=IEA, GO:0005924=IEA} regulation of cell migration, regulation of cytoskeleton organization Z disc, cell-substrate adherens junction, cytoskeleton actin filament binding, structural constituent of muscle Human UniProtKB:Q9Z2J4 NF1 IntAct UniProtKB {GO:0005515=PMID:16374483, GO:0001656=GO_REF:0000024, GO:0048844=GO_REF:0000024, GO:0048593=GO_REF:0000024, GO:0042992=GO_REF:0000024, GO:0007406=GO_REF:0000024, GO:0005622=GO_REF:0000002, GO:0007507=GO_REF:0000024, GO:0046580=GO_REF:0000033, GO:0043525=GO_REF:0000024, GO:0030198=GO_REF:0000024, GO:0000165=GO_REF:0000024, GO:0048745=GO_REF:0000024, GO:0030199=GO_REF:0000024, GO:0048169=GO_REF:0000019, GO:0021897=GO_REF:0000024, GO:0032318=PMID:1570015, GO:0030336=PMID:16648142, GO:0031235=GO_REF:0000033, GO:0045685=GO_REF:0000024, GO:0014065=GO_REF:0000024, GO:0046929=GO_REF:0000019, GO:0048485=GO_REF:0000024, GO:0001649=GO_REF:0000024, GO:0001889=GO_REF:0000024, GO:0043535=PMID:17404841, GO:0032320=GO_REF:0000024, GO:0007519=GO_REF:0000019, GO:0007420=GO_REF:0000024, GO:0032228=GO_REF:0000019, GO:0008542=GO_REF:0000024, GO:0042060=GO_REF:0000024, GO:0007422=GO_REF:0000024, GO:0001952=GO_REF:0000024, GO:0001953=GO_REF:0000019, GO:0030424=PMID:1550670, GO:0030036=GO_REF:0000024, GO:0021987=GO_REF:0000024, GO:0035021=GO_REF:0000019, GO:0030325=GO_REF:0000024, GO:0021510=GO_REF:0000024, GO:0022011=GO_REF:0000024, GO:0048147=GO_REF:0000024, GO:0045124=GO_REF:0000024, GO:0005634=PMID:1550670, GO:0007265=GO_REF:0000024, GO:0030425=PMID:1550670, GO:0043409=GO_REF:0000024, GO:0005737=PMID:1550670, GO:0007154=GO_REF:0000024, GO:0043407=GO_REF:0000024, GO:0051056=GO_REF:0000002, GO:0001666=GO_REF:0000024, GO:0043065=GO_REF:0000024, GO:0014044=GO_REF:0000024, GO:0045765=PMID:17404841, GO:0045762=GO_REF:0000024, GO:0045671=GO_REF:0000019, GO:0048853=GO_REF:0000024, GO:0048712=GO_REF:0000019, GO:0005099=PMID:1570015, GO:0007165=GO_REF:0000002, GO:0050890=PMID:17299016, GO:0001938=GO_REF:0000019, GO:0001937=PMID:17404841, GO:0048715=GO_REF:0000024, GO:0016525=GO_REF:0000019, GO:0043473=GO_REF:0000024, GO:0021915=GO_REF:0000019, GO:0006469=GO_REF:0000024, GO:0005096=GO_REF:0000002} P21359 Neurofibromin protein 20130415 {GO:0005515=IPI, GO:0001656=ISS, GO:0048844=ISS, GO:0048593=ISS, GO:0042992=ISS, GO:0007406=ISS, GO:0005622=IEA, GO:0007507=ISS, GO:0046580=IBA, GO:0043525=ISS, GO:0030198=ISS, GO:0000165=ISS, GO:0048745=ISS, GO:0030199=ISS, GO:0048169=IEA, GO:0021897=ISS, GO:0032318=IMP, GO:0030336=IMP, GO:0031235=IBA, GO:0045685=ISS, GO:0014065=ISS, GO:0046929=IEA, GO:0048485=ISS, GO:0001649=ISS, GO:0001889=ISS, GO:0043535=IMP, GO:0032320=ISS, GO:0007519=IEA, GO:0007420=ISS, GO:0032228=IEA, GO:0008542=ISS, GO:0042060=ISS, GO:0007422=ISS, GO:0001952=ISS, GO:0001953=IEA, GO:0030424=IDA, GO:0030036=ISS, GO:0021987=ISS, GO:0035021=IEA, GO:0030325=ISS, GO:0021510=ISS, GO:0022011=ISS, GO:0048147=ISS, GO:0045124=ISS, GO:0005634=ISS, GO:0007265=ISS, GO:0030425=IDA, GO:0043409=ISS, GO:0005737=ISS, GO:0007154=ISS, GO:0043407=ISS, GO:0051056=IEA, GO:0001666=ISS, GO:0043065=ISS, GO:0014044=ISS, GO:0045765=IMP, GO:0045762=ISS, GO:0045671=IEA, GO:0048853=ISS, GO:0048712=IEA, GO:0005099=IDA, GO:0007165=IEA, GO:0050890=IMP, GO:0001938=IEA, GO:0001937=IMP, GO:0048715=ISS, GO:0016525=IEA, GO:0043473=ISS, GO:0021915=IEA, GO:0006469=ISS, GO:0005096=IEA} MAPK cascade, Ras protein signal transduction, Schwann cell development, actin cytoskeleton organization, adrenal gland development, artery morphogenesis, brain development, camera-type eye morphogenesis, cell communication, cerebral cortex development, cognition, collagen fibril organization, extracellular matrix organization, forebrain astrocyte development, forebrain morphogenesis, heart development, liver development, metanephros development, myelination in peripheral nervous system, negative regulation of MAP kinase activity, negative regulation of MAPK cascade, negative regulation of Rac protein signal transduction, negative regulation of Ras protein signal transduction, negative regulation of angiogenesis, negative regulation of astrocyte differentiation, negative regulation of cell migration, negative regulation of cell-matrix adhesion, negative regulation of endothelial cell proliferation, negative regulation of fibroblast proliferation, negative regulation of neuroblast proliferation, negative regulation of neurotransmitter secretion, negative regulation of oligodendrocyte differentiation, negative regulation of osteoclast differentiation, negative regulation of protein kinase activity, negative regulation of transcription factor import into nucleus, neural tube development, osteoblast differentiation, peripheral nervous system development, phosphatidylinositol 3-kinase cascade, pigmentation, positive regulation of Ras GTPase activity, positive regulation of adenylate cyclase activity, positive regulation of apoptotic process, positive regulation of endothelial cell proliferation, positive regulation of neuron apoptotic process, regulation of Ras GTPase activity, regulation of angiogenesis, regulation of blood vessel endothelial cell migration, regulation of bone resorption, regulation of cell-matrix adhesion, regulation of glial cell differentiation, regulation of long-term neuronal synaptic plasticity, regulation of small GTPase mediated signal transduction, regulation of synaptic transmission, GABAergic, response to hypoxia, signal transduction, skeletal muscle tissue development, smooth muscle tissue development, spinal cord development, sympathetic nervous system development, visual learning, wound healing axon, cytoplasm, dendrite, intracellular, intrinsic to internal side of plasma membrane, nucleus GTPase activator activity, Ras GTPase activator activity, protein binding Human UniProtKB:P05067 NF2 HPA UniProtKB {GO:0008092=GO_REF:0000002, GO:0005515=PMID:21481793, GO:0048471=PMID:17210637, GO:0030036=PMID:9537418, GO:0008285=PMID:17210637, GO:0070306=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0042524=PMID:12444102, GO:0031527=GO_REF:0000039, GO:0005634=PMID:20178741, GO:0032154=GO_REF:0000019, GO:0043409=GO_REF:0000019, GO:0014010=PMID:17353411, GO:0005737=GO_REF:0000052, GO:0005912=GO_REF:0000019, GO:0042475=GO_REF:0000019, GO:0005856=PMID:8379998, GO:0042518=PMID:12444102, GO:0030336=PMID:17210637, GO:0022408=PMID:17210637, GO:0001707=GO_REF:0000019, GO:0005730=PMID:9537418, GO:0032587=GO_REF:0000039, GO:0007398=GO_REF:0000019, GO:0045216=GO_REF:0000019, GO:0030027=GO_REF:0000019, GO:0046426=PMID:12444102, GO:0035330=PMID:20159598, GO:0051496=PMID:9537418, GO:0008156=PMID:17210637, GO:0030864=GO_REF:0000019, GO:0006469=GO_REF:0000019, GO:0005769=PMID:10861283, GO:0001953=PMID:17210637, GO:0019898=GO_REF:0000002} P35240 Merlin protein 20101115 {GO:0008092=IEA, GO:0005515=IPI, GO:0048471=IDA, GO:0030036=IMP, GO:0008285=IMP, GO:0070306=IEA, GO:0005886=IDA, GO:0042524=IDA, GO:0031527=IEA, GO:0005634=IDA, GO:0032154=IEA, GO:0043409=IEA, GO:0014010=IMP, GO:0005737=IDA, GO:0005912=IEA, GO:0042475=IEA, GO:0005856=TAS, GO:0042518=IDA, GO:0030336=TAS, GO:0022408=IDA, GO:0001707=IEA, GO:0005730=IDA, GO:0032587=IEA, GO:0007398=IEA, GO:0045216=IEA, GO:0030027=IEA, GO:0046426=IDA, GO:0035330=IMP, GO:0051496=IMP, GO:0008156=IMP, GO:0030864=IEA, GO:0006469=IEA, GO:0005769=IDA, GO:0001953=TAS, GO:0019898=IEA} Schwann cell proliferation, actin cytoskeleton organization, cell-cell junction organization, ectoderm development, lens fiber cell differentiation, mesoderm formation, negative regulation of DNA replication, negative regulation of JAK-STAT cascade, negative regulation of MAPK cascade, negative regulation of cell migration, negative regulation of cell proliferation, negative regulation of cell-cell adhesion, negative regulation of cell-matrix adhesion, negative regulation of protein kinase activity, negative regulation of tyrosine phosphorylation of Stat3 protein, negative regulation of tyrosine phosphorylation of Stat5 protein, odontogenesis of dentin-containing tooth, positive regulation of stress fiber assembly, regulation of hippo signaling cascade adherens junction, cleavage furrow, cortical actin cytoskeleton, cytoplasm, cytoskeleton, early endosome, extrinsic to membrane, filopodium membrane, lamellipodium, nucleolus, nucleus, perinuclear region of cytoplasm, plasma membrane, ruffle membrane cytoskeletal protein binding, protein binding Human NFAM1 HGNC UniProtKB {GO:0050853=GO_REF:0000019, GO:0045577=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0001819=PMID:12615919, GO:0050861=PMID:15143214, GO:0035556=PMID:12615919, GO:0007165=PMID:12615919, GO:0051091=PMID:12615919, GO:0006954=PMID:12615919, GO:0030183=PMID:15143214, GO:0045121=GO_REF:0000019, GO:0016021=PMID:12615919, GO:0004888=PMID:12615919} Q8NET5 NFAT activation molecule 1 protein 20050127 {GO:0050853=IEA, GO:0045577=IEA, GO:0009986=IEA, GO:0005886=IEA, GO:0001819=NAS, GO:0050861=ISS, GO:0035556=IDA, GO:0007165=IDA, GO:0051091=IDA, GO:0006954=NAS, GO:0030183=ISS, GO:0045121=IEA, GO:0016021=IDA, GO:0004888=IDA} B cell differentiation, B cell receptor signaling pathway, inflammatory response, intracellular signal transduction, positive regulation of B cell receptor signaling pathway, positive regulation of cytokine production, positive regulation of sequence-specific DNA binding transcription factor activity, regulation of B cell differentiation, signal transduction cell surface, integral to membrane, membrane raft, plasma membrane transmembrane signaling receptor activity Human UniProtKB:Q8R4V1 NFASC BHF-UCL UniProtKB {GO:0002175=GO_REF:0000019, GO:0005886=Reactome:REACT_22248, GO:0030913=GO_REF:0000019, GO:0072661=GO_REF:0000019, GO:0042552=GO_REF:0000024, GO:0033270=GO_REF:0000019, GO:0005622=GO_REF:0000024, GO:0043194=GO_REF:0000024, GO:0033010=GO_REF:0000019, GO:0033268=PMID:16652168, GO:0050808=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0007422=GO_REF:0000024, GO:0071205=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037} O94856 Neurofascin protein 20120607 {GO:0002175=IEA, GO:0005886=TAS, GO:0030913=IEA, GO:0072661=IEA, GO:0042552=ISS, GO:0033270=IEA, GO:0005622=ISS, GO:0043194=ISS, GO:0033010=IEA, GO:0033268=TAS, GO:0050808=IEA, GO:0007411=TAS, GO:0007422=ISS, GO:0071205=IEA, GO:0016021=IEA, GO:0007155=IEA} axon guidance, cell adhesion, myelination, paranodal junction assembly, peripheral nervous system development, protein localization to juxtaparanode region of axon, protein localization to paranode region of axon, protein targeting to plasma membrane, synapse organization axon initial segment, integral to membrane, intracellular, node of Ranvier, paranodal junction, paranode region of axon, plasma membrane Human UniProtKB:P97685 NFAT5 IntAct UniProtKB {GO:0005515=PMID:22266867, GO:0007588=PMID:10051678, GO:0007165=PMID:10377394, GO:0005737=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0006366=PMID:10051678, GO:0045944=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0001816=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0070884=GO_REF:0000019} O94916 Nuclear factor of activated T-cells 5 protein 20130415 {GO:0005515=IPI, GO:0007588=TAS, GO:0007165=NAS, GO:0005737=IEA, GO:0003700=IEA, GO:0006366=TAS, GO:0045944=IEA, GO:0005634=IEA, GO:0001816=IEA, GO:0003677=IEA, GO:0070884=IEA} cytokine production, excretion, positive regulation of transcription from RNA polymerase II promoter, regulation of calcineurin-NFAT signaling cascade, signal transduction, transcription from RNA polymerase II promoter cytoplasm, nucleus DNA binding, protein binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:Q92841 NFATC1 BHF-UCL UniProtKB {GO:0005515=PMID:14979875, GO:0005667=GO_REF:0000019, GO:0000790=PMID:15304486, GO:0003700=PMID:9506523, GO:0006366=PMID:8702849, GO:0044212=PMID:14979875, GO:0003705=GO_REF:0000024, GO:0001205=GO_REF:0000024, GO:0005528=PMID:8702849, GO:0005634=GO_REF:0000002, GO:0001837=GO_REF:0000019, GO:0005829=Reactome:REACT_118703, GO:0035556=PMID:14749367, GO:0007507=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0000082=GO_REF:0000019, GO:0005737=GO_REF:0000024, GO:0045944=GO_REF:0000024, GO:0001085=GO_REF:0000024, GO:0000980=GO_REF:0000024, GO:0006816=GO_REF:0000019, GO:0048273=GO_REF:0000024, GO:0045893=PMID:14749367} O95644 Nuclear factor of activated T-cells, cytoplasmic 1 protein 20120404 {GO:0005515=IPI, GO:0005667=IEA, GO:0000790=IDA, GO:0003700=TAS, GO:0006366=TAS, GO:0044212=IDA, GO:0003705=ISS, GO:0001205=ISS, GO:0005528=TAS, GO:0005634=IEA, GO:0001837=IEA, GO:0005829=TAS, GO:0035556=IDA, GO:0007507=IEA, GO:0043565=IEA, GO:0000082=IEA, GO:0005737=ISS, GO:0045944=ISS, GO:0001085=ISS, GO:0000980=ISS, GO:0006816=IEA, GO:0048273=ISS, GO:0045893=IDA} G1/S transition of mitotic cell cycle, calcium ion transport, epithelial to mesenchymal transition, heart development, intracellular signal transduction, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter cytoplasm, cytosol, nuclear chromatin, nucleus, transcription factor complex FK506 binding, RNA polymerase II distal enhancer sequence-specific DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II transcription factor binding, mitogen-activated protein kinase p38 binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding Human UniProtKB:O88942 NFATC2 HPA UniProtKB {GO:0050853=PMID:17875758, GO:0005515=PMID:23105117, GO:0005667=GO_REF:0000019, GO:0006355=PMID:8668213, GO:0003700=PMID:8668213, GO:0005886=GO_REF:0000052, GO:0044212=GO_REF:0000019, GO:0030890=PMID:17875758, GO:0042493=PMID:17875758, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0015629=GO_REF:0000052, GO:0001816=GO_REF:0000019, GO:0003677=PMID:8668213, GO:0006974=PMID:17875758, GO:0006351=GO_REF:0000037, GO:0005829=Reactome:REACT_118703, GO:0043565=GO_REF:0000019, GO:0005737=PMID:12656674, GO:0016477=PMID:21871017, GO:0030529=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0045893=PMID:15790681} Q13469 Nuclear factor of activated T-cells, cytoplasmic 2 protein 20101115 {GO:0050853=IMP, GO:0005515=IPI, GO:0005667=IEA, GO:0006355=TAS, GO:0003700=TAS, GO:0005886=IDA, GO:0044212=IEA, GO:0030890=IMP, GO:0042493=IMP, GO:0005730=IDA, GO:0005634=IDA, GO:0015629=IDA, GO:0001816=IEA, GO:0003677=TAS, GO:0006974=IMP, GO:0006351=IEA, GO:0005829=TAS, GO:0043565=IEA, GO:0005737=IDA, GO:0016477=IDA, GO:0030529=IEA, GO:0045944=IEA, GO:0045893=IDA} B cell receptor signaling pathway, cell migration, cytokine production, positive regulation of B cell proliferation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, response to DNA damage stimulus, response to drug, transcription, DNA-dependent actin cytoskeleton, cytoplasm, cytosol, nucleolus, nucleus, plasma membrane, ribonucleoprotein complex, transcription factor complex DNA binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding Human NFATC2IP UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0006355=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0001816=GO_REF:0000019} Q8NCF5 NFATC2-interacting protein protein 20130413 {GO:0005737=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0001816=IEA} cytokine production, regulation of transcription, DNA-dependent cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 NFATC3 HPA UniProtKB {GO:0071285=GO_REF:0000019, GO:0001569=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0006366=PMID:7739550, GO:0006357=PMID:7749981, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000019, GO:0005829=Reactome:REACT_118703, GO:0007507=GO_REF:0000019, GO:0045333=GO_REF:0000019, GO:0005737=PMID:18815128, GO:0006954=PMID:7739550, GO:0003682=GO_REF:0000019, GO:0045944=PMID:18815128, GO:0055001=GO_REF:0000019, GO:0051145=GO_REF:0000019} Q12968 Nuclear factor of activated T-cells, cytoplasmic 3 protein 20101115 {GO:0071285=IEA, GO:0001569=IEA, GO:0003700=IEA, GO:0005886=IDA, GO:0006366=TAS, GO:0006357=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0005829=TAS, GO:0007507=IEA, GO:0045333=IEA, GO:0005737=IDA, GO:0006954=TAS, GO:0003682=IEA, GO:0045944=IDA, GO:0055001=IEA, GO:0051145=IEA} cellular respiration, cellular response to lithium ion, heart development, inflammatory response, muscle cell development, patterning of blood vessels, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, smooth muscle cell differentiation, transcription from RNA polymerase II promoter cytoplasm, cytosol, nucleolus, nucleus, plasma membrane DNA binding, chromatin binding, sequence-specific DNA binding transcription factor activity Human NFATC4 HPA UniProtKB {GO:0071285=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0001569=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0043065=GO_REF:0000019, GO:0006366=PMID:7749981, GO:0000981=GO_REF:0000019, GO:0003713=PMID:7749981, GO:0005634=GO_REF:0000002, GO:0003677=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0007507=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0034644=GO_REF:0000019, GO:0045333=GO_REF:0000019, GO:0006954=PMID:7749981, GO:0045944=GO_REF:0000019, GO:0045111=GO_REF:0000052, GO:0055001=GO_REF:0000019, GO:0051145=GO_REF:0000019} Q14934 Nuclear factor of activated T-cells, cytoplasmic 4 protein 20101115 {GO:0071285=IEA, GO:0005667=IEA, GO:0001569=IEA, GO:0003700=IEA, GO:0043065=IEA, GO:0006366=TAS, GO:0000981=IEA, GO:0003713=TAS, GO:0005634=IEA, GO:0003677=IEA, GO:0005829=IEA, GO:0007507=IEA, GO:0005737=IDA, GO:0034644=IEA, GO:0045333=IEA, GO:0006954=TAS, GO:0045944=IEA, GO:0045111=IDA, GO:0055001=IEA, GO:0051145=IEA} cellular respiration, cellular response to UV, cellular response to lithium ion, heart development, inflammatory response, muscle cell development, patterning of blood vessels, positive regulation of apoptotic process, positive regulation of transcription from RNA polymerase II promoter, smooth muscle cell differentiation, transcription from RNA polymerase II promoter cytoplasm, cytosol, intermediate filament cytoskeleton, nucleus, transcription factor complex DNA binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity, transcription coactivator activity Human NFE2 HPA UniProtKB {GO:0003700=GO_REF:0000002, GO:0006357=PMID:8355703, GO:0050699=PMID:9305852, GO:0008015=PMID:8355703, GO:0003713=PMID:8355703, GO:0007267=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0007275=PMID:7774011, GO:0006337=PMID:9305852, GO:0030502=GO_REF:0000019, GO:0015629=GO_REF:0000052, GO:0006351=PMID:9305852, GO:0007599=PMID:7774011, GO:0043565=PMID:9305852, GO:0005737=GO_REF:0000039, GO:0047485=PMID:11863372, GO:0007596=Reactome:REACT_604, GO:0016605=GO_REF:0000039, GO:0005654=Reactome:REACT_25340, GO:0045893=PMID:9305852} Q16621 Transcription factor NF-E2 45 kDa subunit protein 20080205 {GO:0003700=IEA, GO:0006357=TAS, GO:0050699=IPI, GO:0008015=TAS, GO:0003713=TAS, GO:0007267=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0007275=TAS, GO:0006337=TAS, GO:0030502=IEA, GO:0015629=IDA, GO:0006351=TAS, GO:0007599=TAS, GO:0043565=TAS, GO:0005737=IEA, GO:0047485=IPI, GO:0007596=TAS, GO:0016605=IEA, GO:0005654=TAS, GO:0045893=TAS} blood circulation, blood coagulation, cell-cell signaling, hemostasis, multicellular organismal development, negative regulation of bone mineralization, nucleosome disassembly, positive regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent PML body, actin cytoskeleton, cytoplasm, nucleolus, nucleoplasm, nucleus WW domain binding, protein N-terminus binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity Human NFE2L1 PINC UniProtKB {GO:0003712=PMID:9826775, GO:0043565=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0006954=PMID:9826775, GO:0003700=GO_REF:0000002, GO:0006366=PMID:9826775, GO:0005789=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0009653=PMID:9501099, GO:0003677=GO_REF:0000002, GO:0006783=PMID:9501099} Q14494 Nuclear factor erythroid 2-related factor 1 protein 20030904 {GO:0003712=TAS, GO:0043565=IEA, GO:0006355=IEA, GO:0006954=TAS, GO:0003700=IEA, GO:0006366=TAS, GO:0005789=IEA, GO:0005634=IEA, GO:0016021=IEA, GO:0009653=TAS, GO:0003677=IEA, GO:0006783=TAS} anatomical structure morphogenesis, heme biosynthetic process, inflammatory response, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter endoplasmic reticulum membrane, integral to membrane, nucleus DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription cofactor activity Human NFE2L2 BHF-UCL UniProtKB {GO:0003700=GO_REF:0000019, GO:0016567=PMID:15983046, GO:0070301=PMID:23043106, GO:0005886=GO_REF:0000052, GO:0006366=PMID:7937919, GO:0005634=PMID:23043106, GO:2000121=GO_REF:0000019, GO:0030968=GO_REF:0000019, GO:0005829=PMID:23043106, GO:0005737=GO_REF:0000052, GO:0045944=GO_REF:0000019, GO:0060548=GO_REF:0000019, GO:0000785=GO_REF:0000019, GO:0036003=PMID:23043106, GO:0071499=PMID:23043106, GO:0001102=PMID:23043106, GO:0005813=GO_REF:0000052, GO:0043066=PMID:23043106, GO:0019904=PMID:11256947, GO:0003677=GO_REF:0000019, GO:0045995=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0030194=GO_REF:0000019, GO:0043161=PMID:15983046, GO:0034599=GO_REF:0000019, GO:2000379=GO_REF:0000019, GO:0010499=PMID:19424503} Q16236 Nuclear factor erythroid 2-related factor 2 protein 20121203 {GO:0003700=IEA, GO:0016567=IDA, GO:0070301=IMP, GO:0005886=IDA, GO:0006366=TAS, GO:0005634=IDA, GO:2000121=IEA, GO:0030968=IEA, GO:0005829=IDA, GO:0005737=IDA, GO:0045944=IEA, GO:0060548=IEA, GO:0000785=IEA, GO:0036003=IMP, GO:0071499=IMP, GO:0001102=IPI, GO:0005813=IDA, GO:0043066=IMP, GO:0019904=IPI, GO:0003677=IEA, GO:0045995=IEA, GO:0043565=IEA, GO:0030194=IEA, GO:0043161=IDA, GO:0034599=IEA, GO:2000379=IEA, GO:0010499=IDA} cellular response to hydrogen peroxide, cellular response to laminar fluid shear stress, cellular response to oxidative stress, endoplasmic reticulum unfolded protein response, negative regulation of apoptotic process, negative regulation of cell death, positive regulation of blood coagulation, positive regulation of reactive oxygen species metabolic process, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter in response to stress, proteasomal ubiquitin-dependent protein catabolic process, proteasomal ubiquitin-independent protein catabolic process, protein ubiquitination, regulation of embryonic development, regulation of removal of superoxide radicals, transcription from RNA polymerase II promoter centrosome, chromatin, cytoplasm, cytosol, nucleus, plasma membrane DNA binding, RNA polymerase II activating transcription factor binding, protein domain specific binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human NFE2L3 PINC UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0006366=PMID:10037736, GO:0003713=PMID:10037736, GO:0005634=GO_REF:0000039} Q9Y4A8 Nuclear factor erythroid 2-related factor 3 protein 20030904 {GO:0043565=IEA, GO:0003700=IEA, GO:0006366=TAS, GO:0003713=TAS, GO:0005634=IEA} transcription from RNA polymerase II promoter nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity Human NFIA HPA UniProtKB {GO:0006260=GO_REF:0000037, GO:0014070=GO_REF:0000019, GO:0006355=PMID:7590749, GO:0030054=GO_REF:0000052, GO:0003700=PMID:7590749, GO:0045944=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0019079=PMID:7590749, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0008134=PMID:15684392} Q12857 Nuclear factor 1 A-type protein 20101115 {GO:0006260=IEA, GO:0014070=IEA, GO:0006355=NAS, GO:0030054=IDA, GO:0003700=NAS, GO:0045944=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0019079=NAS, GO:0003677=IEA, GO:0006351=IEA, GO:0008134=IPI} DNA replication, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, response to organic cyclic compound, transcription, DNA-dependent, viral genome replication cell junction, nucleolus, nucleus DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human NFIB InterPro UniProtKB {GO:0021960=GO_REF:0000024, GO:2000791=GO_REF:0000024, GO:0003700=GO_REF:0000002, GO:0006366=PMID:9099724, GO:0000981=PMID:9099724, GO:0071679=GO_REF:0000024, GO:0044300=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000002, GO:0003677=GO_REF:0000038, GO:0006351=GO_REF:0000038, GO:0060509=GO_REF:0000024, GO:0006260=GO_REF:0000002, GO:2000795=GO_REF:0000024, GO:0002062=GO_REF:0000024, GO:0061141=GO_REF:0000024, GO:0045944=PMID:9099724, GO:0021740=GO_REF:0000024, GO:0010001=GO_REF:0000024, GO:0060486=GO_REF:0000024, GO:0060510=GO_REF:0000024} Q5W0Y9 Nuclear factor 1 B-type protein 20130413 {GO:0021960=ISS, GO:2000791=ISS, GO:0003700=IEA, GO:0006366=IDA, GO:0000981=IDA, GO:0071679=ISS, GO:0044300=ISS, GO:0005730=IDA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0060509=ISS, GO:0006260=IEA, GO:2000795=ISS, GO:0002062=ISS, GO:0061141=ISS, GO:0045944=IDA, GO:0021740=ISS, GO:0010001=ISS, GO:0060486=ISS, GO:0060510=ISS} Clara cell differentiation, DNA replication, Type I pneumocyte differentiation, Type II pneumocyte differentiation, anterior commissure morphogenesis, chondrocyte differentiation, commissural neuron axon guidance, glial cell differentiation, lung ciliated cell differentiation, negative regulation of epithelial cell proliferation involved in lung morphogenesis, negative regulation of mesenchymal cell proliferation involved in lung development, positive regulation of transcription from RNA polymerase II promoter, principal sensory nucleus of trigeminal nerve development, transcription from RNA polymerase II promoter, transcription, DNA-dependent cerebellar mossy fiber, nucleolus, nucleus DNA binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity Human InterPro:IPR000647|InterPro:IPR020604 NFIC MGI UniProtKB {GO:0006260=GO_REF:0000037, GO:0003700=PMID:1524678, GO:0006366=PMID:8710515, GO:0045944=PMID:1524678, GO:0005634=GO_REF:0000039, GO:0000122=PMID:1524678, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000038} P08651 Nuclear factor 1 C-type protein 20080919 {GO:0006260=IEA, GO:0003700=IDA, GO:0006366=TAS, GO:0045944=IDA, GO:0005634=IEA, GO:0000122=IGI, GO:0003677=IEA, GO:0006351=IEA} DNA replication, negative regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity Human NFIL3 HPA UniProtKB {GO:0010628=GO_REF:0000019, GO:0001078=PMID:20093779, GO:0006955=PMID:7565758, GO:0000977=PMID:20093779, GO:0003700=PMID:7565758, GO:0006366=PMID:7565758, GO:0003714=PMID:1620116, GO:0007623=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0000122=PMID:20093779, GO:0003677=PMID:1620116, GO:0000979=GO_REF:0000019} Q16649 Nuclear factor interleukin-3-regulated protein protein 20080818 {GO:0010628=IEA, GO:0001078=IDA, GO:0006955=TAS, GO:0000977=IDA, GO:0003700=TAS, GO:0006366=TAS, GO:0003714=TAS, GO:0007623=IEA, GO:0005634=IDA, GO:0000122=IMP, GO:0003677=TAS, GO:0000979=IEA} circadian rhythm, immune response, negative regulation of transcription from RNA polymerase II promoter, positive regulation of gene expression, transcription from RNA polymerase II promoter nucleus DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, RNA polymerase II core promoter sequence-specific DNA binding, RNA polymerase II regulatory region sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human NFIX PINC UniProtKB {GO:0006260=GO_REF:0000037, GO:0003700=PMID:8340106, GO:0006366=PMID:7937100, GO:0003705=PMID:7937100, GO:0045944=PMID:19706729, GO:0005634=GO_REF:0000039, GO:0000122=PMID:19706729, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000038} Q14938 Nuclear factor 1 X-type protein 20030904 {GO:0006260=IEA, GO:0003700=TAS, GO:0006366=TAS, GO:0003705=TAS, GO:0045944=IDA, GO:0005634=IEA, GO:0000122=IDA, GO:0003677=IEA, GO:0006351=IEA} DNA replication, negative regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, sequence-specific DNA binding transcription factor activity Human NFKB1 HPA UniProtKB {GO:0005515=PMID:21988832, GO:0003700=GO_REF:0000002, GO:0006366=PMID:1992489, GO:0044212=PMID:16938301, GO:0090263=PMID:20018240, GO:0001818=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0002756=Reactome:REACT_6809, GO:0003690=GO_REF:0000019, GO:0031072=GO_REF:0000019, GO:0002755=Reactome:REACT_27215, GO:0006979=GO_REF:0000019, GO:0033256=PMID:16938301, GO:0000975=PMID:17426251, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0010744=PMID:16938301, GO:0034134=Reactome:REACT_7980, GO:0000122=PMID:16938301, GO:0002224=Reactome:REACT_9020, GO:0032269=PMID:16938301, GO:0043234=GO_REF:0000019, GO:0045083=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0071347=PMID:12958148, GO:0005654=Reactome:REACT_118705, GO:0034166=Reactome:REACT_9027, GO:0035666=Reactome:REACT_25281, GO:0045893=PMID:17426251, GO:0046688=GO_REF:0000019, GO:0045892=GO_REF:0000019, GO:0034162=Reactome:REACT_9047, GO:0008134=PMID:18270204, GO:0032375=PMID:16938301, GO:0050852=Reactome:REACT_12526, GO:0034142=Reactome:REACT_6894, GO:0031293=Reactome:REACT_13443, GO:0005634=GO_REF:0000052, GO:0005829=Reactome:REACT_118856, GO:0005739=GO_REF:0000052, GO:0009617=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0006954=PMID:1992489, GO:0051092=Reactome:REACT_21281, GO:0045944=GO_REF:0000019, GO:0032481=Reactome:REACT_118823, GO:0034138=Reactome:REACT_6783, GO:0043066=Reactome:REACT_13537, GO:0048011=Reactome:REACT_13776, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0010884=PMID:16938301, GO:0043565=GO_REF:0000019, GO:0001071=PMID:17426251, GO:0071260=PMID:19593445, GO:0034146=Reactome:REACT_9061, GO:0010956=PMID:15243130, GO:0010957=PMID:15243130} P19838 Nuclear factor NF-kappa-B p105 subunit protein 20120912 {GO:0005515=IPI, GO:0003700=IEA, GO:0006366=TAS, GO:0044212=IDA, GO:0090263=IMP, GO:0001818=IEA, GO:0042803=IEA, GO:0002756=TAS, GO:0003690=IEA, GO:0031072=IEA, GO:0002755=TAS, GO:0006979=IEA, GO:0033256=TAS, GO:0000975=IDA, GO:0038124=TAS, GO:0038123=TAS, GO:0010744=IC, GO:0034134=TAS, GO:0000122=IC, GO:0002224=TAS, GO:0032269=IC, GO:0043234=IEA, GO:0045083=IEA, GO:0045087=TAS, GO:0071347=IEP, GO:0005654=TAS, GO:0034166=TAS, GO:0035666=TAS, GO:0045893=IDA, GO:0046688=IEA, GO:0045892=IEA, GO:0034162=TAS, GO:0008134=IDA, GO:0032375=IC, GO:0050852=TAS, GO:0034142=TAS, GO:0031293=TAS, GO:0005634=IDA, GO:0005829=TAS, GO:0005739=IDA, GO:0009617=IEA, GO:0005737=IDA, GO:0006954=TAS, GO:0051092=TAS, GO:0045944=IEA, GO:0032481=TAS, GO:0034138=TAS, GO:0043066=TAS, GO:0048011=TAS, GO:0005730=IDA, GO:0006915=IEA, GO:0010884=IC, GO:0043565=IEA, GO:0001071=IDA, GO:0071260=IEP, GO:0034146=TAS, GO:0010956=IDA, GO:0010957=IC} MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, T cell receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, apoptotic process, cellular response to interleukin-1, cellular response to mechanical stimulus, inflammatory response, innate immune response, membrane protein intracellular domain proteolysis, negative regulation of apoptotic process, negative regulation of calcidiol 1-monooxygenase activity, negative regulation of cellular protein metabolic process, negative regulation of cholesterol transport, negative regulation of cytokine production, negative regulation of interleukin-12 biosynthetic process, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, negative regulation of vitamin D biosynthetic process, neurotrophin TRK receptor signaling pathway, positive regulation of NF-kappaB transcription factor activity, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of lipid storage, positive regulation of macrophage derived foam cell differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of type I interferon production, response to bacterium, response to copper ion, response to oxidative stress, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, transcription from RNA polymerase II promoter I-kappaB/NF-kappaB complex, cytoplasm, cytosol, mitochondrion, nucleolus, nucleoplasm, nucleus, protein complex double-stranded DNA binding, heat shock protein binding, nucleic acid binding transcription factor activity, protein binding, protein homodimerization activity, regulatory region DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding Human NFKB2 HPA UniProtKB {GO:0005515=PMID:11239468, GO:0003700=GO_REF:0000002, GO:0034142=Reactome:REACT_6894, GO:0005634=GO_REF:0000052, GO:0048536=GO_REF:0000019, GO:0005829=Reactome:REACT_6906, GO:0002756=Reactome:REACT_6809, GO:0005737=GO_REF:0000052, GO:0051092=Reactome:REACT_21281, GO:0030198=GO_REF:0000019, GO:0002755=Reactome:REACT_27215, GO:0032481=Reactome:REACT_118823, GO:0033257=PMID:9407099, GO:0002467=GO_REF:0000019, GO:0034138=Reactome:REACT_6783, GO:0006355=PMID:8360178, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0002268=GO_REF:0000019, GO:0034134=Reactome:REACT_7980, GO:0003713=PMID:1876189, GO:0005730=GO_REF:0000052, GO:0002224=Reactome:REACT_9020, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0005654=Reactome:REACT_6906, GO:0034166=Reactome:REACT_9027, GO:0035666=Reactome:REACT_25281, GO:0034146=Reactome:REACT_9061, GO:0034162=Reactome:REACT_9047} Q00653 Nuclear factor NF-kappa-B p100 subunit protein 20080818 {GO:0005515=IPI, GO:0003700=IEA, GO:0034142=TAS, GO:0005634=IDA, GO:0048536=IEA, GO:0005829=TAS, GO:0002756=TAS, GO:0005737=IDA, GO:0051092=TAS, GO:0030198=IEA, GO:0002755=TAS, GO:0032481=TAS, GO:0033257=IDA, GO:0002467=IEA, GO:0034138=TAS, GO:0006355=IDA, GO:0038124=TAS, GO:0038123=TAS, GO:0002268=IEA, GO:0034134=TAS, GO:0003713=TAS, GO:0005730=IDA, GO:0002224=TAS, GO:0003677=IEA, GO:0006351=IEA, GO:0045087=TAS, GO:0005654=TAS, GO:0034166=TAS, GO:0035666=TAS, GO:0034146=TAS, GO:0034162=TAS} MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, extracellular matrix organization, follicular dendritic cell differentiation, germinal center formation, innate immune response, positive regulation of NF-kappaB transcription factor activity, positive regulation of type I interferon production, regulation of transcription, DNA-dependent, spleen development, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, transcription, DNA-dependent Bcl3/NF-kappaB2 complex, cytoplasm, cytosol, nucleolus, nucleoplasm, nucleus DNA binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity Human NFKBIA BHF-UCL UniProtKB {GO:0005515=PMID:9452483, GO:0042994=PMID:1493333, GO:0032403=GO_REF:0000019, GO:0042802=PMID:16951195, GO:0002756=Reactome:REACT_6809, GO:0031072=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0002755=Reactome:REACT_27215, GO:0031663=GO_REF:0000019, GO:0031625=PMID:9859996, GO:0033256=PMID:16938301, GO:0000060=GO_REF:0000019, GO:0045746=GO_REF:0000019, GO:0038124=Reactome:REACT_8006, GO:0010745=PMID:16938301, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0070431=GO_REF:0000019, GO:0002224=Reactome:REACT_9020, GO:0043392=PMID:3140380, GO:0032270=PMID:16938301, GO:0043234=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0008139=PMID:1493333, GO:0034166=Reactome:REACT_9027, GO:0035666=Reactome:REACT_25281, GO:0045893=GO_REF:0000019, GO:0019899=PMID:16648481, GO:0034162=Reactome:REACT_9047, GO:0008134=PMID:10928981, GO:0042345=PMID:3140380, GO:0050852=Reactome:REACT_12526, GO:0034142=Reactome:REACT_6894, GO:0005886=GO_REF:0000052, GO:0005634=PMID:16648481, GO:0070427=GO_REF:0000019, GO:0010875=PMID:16938301, GO:0005829=Reactome:REACT_118856, GO:0005737=GO_REF:0000052, GO:0051092=Reactome:REACT_21281, GO:0045638=GO_REF:0000019, GO:0045944=PMID:16938301, GO:0032481=Reactome:REACT_118823, GO:0034138=Reactome:REACT_6783, GO:0043066=Reactome:REACT_13537, GO:0048011=Reactome:REACT_13776, GO:0051059=PMID:11931770, GO:0007253=PMID:16938301, GO:0006915=PMID:10747850, GO:0032088=PMID:11931770, GO:0010888=PMID:16938301, GO:0070417=PMID:16750872, GO:0019048=GO_REF:0000037, GO:0032495=GO_REF:0000019, GO:0034146=Reactome:REACT_9061, GO:0043330=GO_REF:0000019} P25963 NF-kappa-B inhibitor alpha protein 20110207 {GO:0005515=IPI, GO:0042994=IDA, GO:0032403=IEA, GO:0042802=IPI, GO:0002756=TAS, GO:0031072=IEA, GO:0042127=IEA, GO:0002755=TAS, GO:0031663=IEA, GO:0031625=IPI, GO:0033256=TAS, GO:0000060=IEA, GO:0045746=IEA, GO:0038124=TAS, GO:0010745=IMP, GO:0038123=TAS, GO:0034134=TAS, GO:0070431=IEA, GO:0002224=TAS, GO:0043392=NAS, GO:0032270=IMP, GO:0043234=IEA, GO:0045087=TAS, GO:0008139=IPI, GO:0034166=TAS, GO:0035666=TAS, GO:0045893=IEA, GO:0019899=IPI, GO:0034162=TAS, GO:0008134=TAS, GO:0042345=NAS, GO:0050852=TAS, GO:0034142=TAS, GO:0005886=IDA, GO:0005634=IDA, GO:0070427=IEA, GO:0010875=IMP, GO:0005829=TAS, GO:0005737=IDA, GO:0051092=TAS, GO:0045638=IEA, GO:0045944=IMP, GO:0032481=TAS, GO:0034138=TAS, GO:0043066=TAS, GO:0048011=TAS, GO:0051059=IDA, GO:0007253=IMP, GO:0006915=TAS, GO:0032088=IDA, GO:0010888=IMP, GO:0070417=NAS, GO:0019048=IEA, GO:0032495=IEA, GO:0034146=TAS, GO:0043330=IEA} MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, T cell receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, apoptotic process, cellular response to cold, cytoplasmic sequestering of NF-kappaB, cytoplasmic sequestering of transcription factor, innate immune response, lipopolysaccharide-mediated signaling pathway, negative regulation of DNA binding, negative regulation of NF-kappaB transcription factor activity, negative regulation of Notch signaling pathway, negative regulation of apoptotic process, negative regulation of lipid storage, negative regulation of macrophage derived foam cell differentiation, negative regulation of myeloid cell differentiation, neurotrophin TRK receptor signaling pathway, nucleotide-binding oligomerization domain containing 1 signaling pathway, nucleotide-binding oligomerization domain containing 2 signaling pathway, positive regulation of NF-kappaB transcription factor activity, positive regulation of cellular protein metabolic process, positive regulation of cholesterol efflux, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of type I interferon production, protein import into nucleus, translocation, regulation of NF-kappaB import into nucleus, regulation of cell proliferation, response to exogenous dsRNA, response to muramyl dipeptide, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, virus-host interaction I-kappaB/NF-kappaB complex, cytoplasm, cytosol, nucleus, plasma membrane, protein complex NF-kappaB binding, enzyme binding, heat shock protein binding, identical protein binding, nuclear localization sequence binding, protein binding, protein complex binding, transcription factor binding, ubiquitin protein ligase binding Human NFKBIB IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0038124=Reactome:REACT_8006, GO:0034142=Reactome:REACT_6894, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0003713=PMID:7776974, GO:0005634=GO_REF:0000039, GO:0002224=Reactome:REACT_9020, GO:0006351=PMID:7776974, GO:0005829=Reactome:REACT_118856, GO:0007165=PMID:7776974, GO:0002756=Reactome:REACT_6809, GO:0051092=Reactome:REACT_21281, GO:0045087=Reactome:REACT_6802, GO:0002755=Reactome:REACT_27215, GO:0034166=Reactome:REACT_9027, GO:0032481=Reactome:REACT_118823, GO:0035666=Reactome:REACT_25281, GO:0004871=PMID:7776974, GO:0034146=Reactome:REACT_9061, GO:0034138=Reactome:REACT_6783, GO:0034162=Reactome:REACT_9047} Q15653 NF-kappa-B inhibitor beta protein 20130415 {GO:0005515=IPI, GO:0038124=TAS, GO:0034142=TAS, GO:0038123=TAS, GO:0034134=TAS, GO:0003713=TAS, GO:0005634=IEA, GO:0002224=TAS, GO:0006351=TAS, GO:0005829=TAS, GO:0007165=TAS, GO:0002756=TAS, GO:0051092=TAS, GO:0045087=TAS, GO:0002755=TAS, GO:0034166=TAS, GO:0032481=TAS, GO:0035666=TAS, GO:0004871=TAS, GO:0034146=TAS, GO:0034138=TAS, GO:0034162=TAS} MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, innate immune response, positive regulation of NF-kappaB transcription factor activity, positive regulation of type I interferon production, signal transduction, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, transcription, DNA-dependent cytosol, nucleus protein binding, signal transducer activity, transcription coactivator activity Human UniProtKB:Q04206 NFKBIE Reactome UniProtKB {GO:0005737=PMID:9135156, GO:0048471=GO_REF:0000019, GO:0005794=GO_REF:0000019, GO:0042942=GO_REF:0000019, GO:0042994=PMID:9135156, GO:0005829=Reactome:REACT_118856} O00221 NF-kappa-B inhibitor epsilon protein 20110809 {GO:0005737=TAS, GO:0048471=IEA, GO:0005794=IEA, GO:0042942=IEA, GO:0042994=TAS, GO:0005829=TAS} D-serine transport, cytoplasmic sequestering of transcription factor Golgi apparatus, cytoplasm, cytosol, perinuclear region of cytoplasm Human NFKBIL1 PINC UniProtKB {GO:0005515=PMID:20829348, GO:0071222=PMID:20829348, GO:0034122=PMID:20829348, GO:0007249=GO_REF:0000019, GO:0032720=PMID:20829348, GO:0042994=PMID:8081366, GO:0032088=PMID:20829348, GO:0005634=PMID:20829348, GO:0031665=PMID:20829348, GO:0005829=GO_REF:0000019} Q9UBC1 NF-kappa-B inhibitor-like protein 1 protein 20050308 {GO:0005515=IPI, GO:0071222=IDA, GO:0034122=IDA, GO:0007249=IEA, GO:0032720=IMP, GO:0042994=TAS, GO:0032088=IDA, GO:0005634=IDA, GO:0031665=IDA, GO:0005829=IEA} I-kappaB kinase/NF-kappaB cascade, cellular response to lipopolysaccharide, cytoplasmic sequestering of transcription factor, negative regulation of NF-kappaB transcription factor activity, negative regulation of lipopolysaccharide-mediated signaling pathway, negative regulation of toll-like receptor signaling pathway, negative regulation of tumor necrosis factor production cytosol, nucleus protein binding Human NFKBIZ UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0006954=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q9BYH8 NF-kappa-B inhibitor zeta protein 20130413 {GO:0006355=IEA, GO:0006954=IEA, GO:0005634=IEA, GO:0006351=IEA} inflammatory response, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus Human UniProtKB-SubCell:SL-0191 NFRKB HPA UniProtKB {GO:0031011=PMID:18922472, GO:0006355=GO_REF:0000037, GO:0006954=PMID:1777480, GO:0006281=GO_REF:0000037, GO:0006366=PMID:1777480, GO:0005730=GO_REF:0000052, GO:0006310=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0002020=PMID:18922472, GO:0003677=GO_REF:0000037} Q6P4R8 Nuclear factor related to kappa-B-binding protein protein 20080205 {GO:0031011=IDA, GO:0006355=IEA, GO:0006954=TAS, GO:0006281=IEA, GO:0006366=TAS, GO:0005730=IDA, GO:0006310=IEA, GO:0005634=IDA, GO:0002020=IPI, GO:0003677=IEA} DNA recombination, DNA repair, inflammatory response, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter Ino80 complex, nucleolus, nucleus DNA binding, protease binding NOT Human NFS1 Reactome UniProtKB {GO:0005515=PMID:18650437, GO:0006534=GO_REF:0000002, GO:0006767=Reactome:REACT_11238, GO:0005634=PMID:16847322, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0042803=PMID:16527810, GO:0005829=Reactome:REACT_24937, GO:0032324=Reactome:REACT_25073, GO:0005739=PMID:9885568, GO:0000096=PMID:9885568, GO:0006461=PMID:9885568, GO:0006766=Reactome:REACT_11193, GO:0005759=Reactome:REACT_150385, GO:0006777=GO_REF:0000037, GO:0031071=Reactome:REACT_24937, GO:0030170=GO_REF:0000002, GO:0018283=PMID:16847322} Q9Y697 Cysteine desulfurase, mitochondrial protein 20110609 {GO:0005515=IPI, GO:0006534=IEA, GO:0006767=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0003824=IEA, GO:0042803=IDA, GO:0005829=TAS, GO:0032324=TAS, GO:0005739=TAS, GO:0000096=TAS, GO:0006461=TAS, GO:0006766=TAS, GO:0005759=TAS, GO:0006777=IEA, GO:0031071=TAS, GO:0030170=IEA, GO:0018283=IDA} Mo-molybdopterin cofactor biosynthetic process, cysteine metabolic process, iron incorporation into metallo-sulfur cluster, molybdopterin cofactor biosynthetic process, protein complex assembly, small molecule metabolic process, sulfur amino acid metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cytosol, mitochondrial matrix, mitochondrion, nucleus catalytic activity, cysteine desulfurase activity, protein binding, protein homodimerization activity, pyridoxal phosphate binding Human NFU1 HPA UniProtKB {GO:0005515=PMID:22190034, GO:0005739=PMID:12886008, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0051539=PMID:12886008, GO:0051536=GO_REF:0000002, GO:0016226=PMID:12886008, GO:0005506=PMID:12886008, GO:0005634=GO_REF:0000052, GO:0005829=PMID:12915448} Q9UMS0 NFU1 iron-sulfur cluster scaffold homolog, mitochondrial protein 20110516 {GO:0005515=IPI, GO:0005739=IDA, GO:0005813=IDA, GO:0005737=IDA, GO:0051539=IDA, GO:0051536=IEA, GO:0016226=IDA, GO:0005506=IDA, GO:0005634=IDA, GO:0005829=IDA} iron-sulfur cluster assembly centrosome, cytoplasm, cytosol, mitochondrion, nucleus 4 iron, 4 sulfur cluster binding, iron ion binding, iron-sulfur cluster binding, protein binding Human NFX1 PINC UniProtKB {GO:0006954=PMID:7964459, GO:0003700=GO_REF:0000002, GO:0006366=PMID:7964459, GO:0019048=GO_REF:0000037, GO:0016874=GO_REF:0000037, GO:0045347=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0000122=GO_REF:0000019, GO:0003677=GO_REF:0000037} Q12986 Transcriptional repressor NF-X1 protein 20030904 {GO:0006954=TAS, GO:0003700=IEA, GO:0006366=TAS, GO:0019048=IEA, GO:0016874=IEA, GO:0045347=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0000122=IEA, GO:0003677=IEA} inflammatory response, negative regulation of MHC class II biosynthetic process, negative regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter, virus-host interaction nucleus DNA binding, ligase activity, sequence-specific DNA binding transcription factor activity, zinc ion binding Human NFXL1 UniProtKB UniProtKB {GO:0003700=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q6ZNB6 NF-X1-type zinc finger protein NFXL1 protein 20130413 {GO:0003700=IEA, GO:0008270=IEA, GO:0005634=IEA, GO:0016021=IEA} integral to membrane, nucleus sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB-KW:KW-0812 NFYA IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0006355=PMID:15243141, GO:0016602=PMID:15243141, GO:0003700=GO_REF:0000019, GO:0006366=PMID:2000400, GO:0045944=GO_REF:0000019, GO:0005654=Reactome:REACT_147902, GO:0005634=PMID:15964792, GO:0044281=Reactome:REACT_111217, GO:0003677=PMID:15243141, GO:0044255=Reactome:REACT_22279} P23511 Nuclear transcription factor Y subunit alpha protein 20130415 {GO:0005515=IPI, GO:0006355=IDA, GO:0016602=IDA, GO:0003700=IEA, GO:0006366=TAS, GO:0045944=IEA, GO:0005654=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0003677=IDA, GO:0044255=TAS} cellular lipid metabolic process, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, small molecule metabolic process, transcription from RNA polymerase II promoter CCAAT-binding factor complex, nucleoplasm, nucleus DNA binding, protein binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:Q92624 NFYB IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0006355=PMID:15243141, GO:0003700=GO_REF:0000019, GO:0046982=GO_REF:0000002, GO:0005634=PMID:15964792, GO:0044281=Reactome:REACT_111217, GO:0003677=PMID:15243141, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0016602=PMID:15243141, GO:0070491=PMID:19223331, GO:0005654=Reactome:REACT_147902, GO:0045893=GO_REF:0000019, GO:0044255=Reactome:REACT_22279} P25208 Nuclear transcription factor Y subunit beta protein 20130415 {GO:0005515=IPI, GO:0006355=IDA, GO:0003700=IEA, GO:0046982=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0003677=IDA, GO:0006351=IEA, GO:0043565=IEA, GO:0016602=IDA, GO:0070491=IPI, GO:0005654=TAS, GO:0045893=IEA, GO:0044255=TAS} cellular lipid metabolic process, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, small molecule metabolic process, transcription, DNA-dependent CCAAT-binding factor complex, nucleoplasm, nucleus DNA binding, protein binding, protein heterodimerization activity, repressing transcription factor binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:Q13952 NFYC ENSEMBL UniProtKB {GO:0005515=PMID:21988832, GO:0006355=PMID:15243141, GO:0003700=GO_REF:0000019, GO:0046982=GO_REF:0000002, GO:0006357=PMID:10446203, GO:0003713=PMID:10446203, GO:0005634=PMID:15964792, GO:0044281=Reactome:REACT_111217, GO:0003677=PMID:15243141, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0016602=GO_REF:0000002, GO:0006457=PMID:10446203, GO:0005654=Reactome:REACT_147902, GO:0045893=GO_REF:0000019, GO:0044255=Reactome:REACT_22279} Q5T6K7 Nuclear transcription factor Y subunit gamma protein 20130413 {GO:0005515=IPI, GO:0006355=IDA, GO:0003700=IEA, GO:0046982=IEA, GO:0006357=TAS, GO:0003713=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0003677=IDA, GO:0006351=IEA, GO:0043565=IEA, GO:0016602=IEA, GO:0006457=TAS, GO:0005654=TAS, GO:0045893=IEA, GO:0044255=TAS} cellular lipid metabolic process, positive regulation of transcription, DNA-dependent, protein folding, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, small molecule metabolic process, transcription, DNA-dependent CCAAT-binding factor complex, nucleoplasm, nucleus DNA binding, protein binding, protein heterodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity Human Ensembl:ENSMUSP00000112810 NGB UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0005833=GO_REF:0000029, GO:0019825=GO_REF:0000002, GO:0005506=GO_REF:0000002, GO:0005344=PMID:11029004, GO:0043204=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0015671=PMID:11029004, GO:0020037=GO_REF:0000002} Q9NPG2 Neuroglobin protein 20030403 {GO:0005739=IEA, GO:0005833=NAS, GO:0019825=IEA, GO:0005506=IEA, GO:0005344=TAS, GO:0043204=IEA, GO:0006915=IEA, GO:0015671=NAS, GO:0020037=IEA} apoptotic process, oxygen transport hemoglobin complex, mitochondrion, perikaryon heme binding, iron ion binding, oxygen binding, oxygen transporter activity Human NGDN UniProtKB UniProtKB {GO:0030424=GO_REF:0000039, GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0030175=GO_REF:0000039, GO:0030425=GO_REF:0000039, GO:0006417=GO_REF:0000037} Q8NEJ9 Neuroguidin protein 20130413 {GO:0030424=IEA, GO:0005737=IEA, GO:0005634=IEA, GO:0030175=IEA, GO:0030425=IEA, GO:0006417=IEA} regulation of translation axon, cytoplasm, dendrite, filopodium, nucleus Human UniProtKB-SubCell:SL-0283 NGEF HPA UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0005886=GO_REF:0000052, GO:0048013=GO_REF:0000024, GO:0035023=GO_REF:0000002, GO:0009987=GO_REF:0000019, GO:0007264=Reactome:REACT_11044, GO:0006915=Reactome:REACT_13638, GO:0097190=Reactome:REACT_13720, GO:0043087=GO_REF:0000024, GO:0030426=GO_REF:0000039, GO:0005829=Reactome:REACT_19216, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0005089=GO_REF:0000002, GO:0061002=GO_REF:0000024} Q8N5V2 Ephexin-1 protein 20080818 {GO:0051056=TAS, GO:0048011=TAS, GO:0005886=IDA, GO:0048013=ISS, GO:0035023=IEA, GO:0009987=IEA, GO:0007264=TAS, GO:0006915=TAS, GO:0097190=TAS, GO:0043087=ISS, GO:0030426=IEA, GO:0005829=TAS, GO:0005622=IEA, GO:0005737=IDA, GO:0005543=IEA, GO:0005089=IEA, GO:0061002=ISS} apoptotic process, apoptotic signaling pathway, cellular process, ephrin receptor signaling pathway, negative regulation of dendritic spine morphogenesis, neurotrophin TRK receptor signaling pathway, regulation of GTPase activity, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytoplasm, cytosol, growth cone, intracellular, plasma membrane Rho guanyl-nucleotide exchange factor activity, phospholipid binding Human NGF BHF-UCL UniProtKB {GO:0032455=Reactome:REACT_11062, GO:0008344=GO_REF:0000019, GO:0007264=Reactome:REACT_12077, GO:0045773=GO_REF:0000019, GO:0043434=GO_REF:0000019, GO:0007265=Reactome:REACT_12033, GO:0007202=Reactome:REACT_12079, GO:0005615=GO_REF:0000019, GO:0031175=GO_REF:0000019, GO:0000186=Reactome:REACT_12005, GO:0043524=GO_REF:0000019, GO:0051091=GO_REF:0000019, GO:0006954=GO_REF:0000019, GO:0051602=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0007613=GO_REF:0000019, GO:0031954=GO_REF:0000019, GO:0009314=GO_REF:0000019, GO:0048011=Reactome:REACT_13776, GO:0043066=Reactome:REACT_13537, GO:0005796=Reactome:REACT_10058, GO:0048015=Reactome:REACT_12464, GO:0042493=GO_REF:0000019, GO:0010193=GO_REF:0000019, GO:0006915=Reactome:REACT_13643, GO:0046928=GO_REF:0000019, GO:2000648=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0005576=Reactome:REACT_13785, GO:0045786=Reactome:REACT_13695, GO:0097190=Reactome:REACT_13806, GO:0005163=PMID:14985763, GO:0019233=GO_REF:0000019, GO:0051388=GO_REF:0000019, GO:0009612=GO_REF:0000019, GO:0045666=GO_REF:0000019, GO:0007422=GO_REF:0000019, GO:0050772=Reactome:REACT_13779, GO:0005057=GO_REF:0000019, GO:0050770=Reactome:REACT_13620, GO:0007169=Reactome:REACT_11064, GO:0008083=GO_REF:0000037, GO:0005768=Reactome:REACT_12063, GO:0035094=GO_REF:0000019} P01138 Beta-nerve growth factor protein 20080310 {GO:0032455=TAS, GO:0008344=IEA, GO:0007264=TAS, GO:0045773=IEA, GO:0043434=IEA, GO:0007265=TAS, GO:0007202=TAS, GO:0005615=IEA, GO:0031175=IEA, GO:0000186=TAS, GO:0043524=IEA, GO:0051091=IEA, GO:0006954=IEA, GO:0051602=IEA, GO:0032496=IEA, GO:0007613=IEA, GO:0031954=IEA, GO:0009314=IEA, GO:0048011=TAS, GO:0043066=TAS, GO:0005796=TAS, GO:0048015=TAS, GO:0042493=IEA, GO:0010193=IEA, GO:0006915=TAS, GO:0046928=IEA, GO:2000648=IEA, GO:0051384=IEA, GO:0005576=TAS, GO:0045786=TAS, GO:0097190=TAS, GO:0005163=IPI, GO:0019233=IEA, GO:0051388=IEA, GO:0009612=IEA, GO:0045666=IEA, GO:0007422=IEA, GO:0050772=TAS, GO:0005057=IEA, GO:0050770=TAS, GO:0007169=TAS, GO:0008083=IEA, GO:0005768=TAS, GO:0035094=IEA} Ras protein signal transduction, activation of MAPKK activity, activation of phospholipase C activity, adult locomotory behavior, apoptotic process, apoptotic signaling pathway, inflammatory response, memory, negative regulation of apoptotic process, negative regulation of cell cycle, negative regulation of neuron apoptotic process, nerve growth factor processing, neuron projection development, neurotrophin TRK receptor signaling pathway, peripheral nervous system development, phosphatidylinositol-mediated signaling, positive regulation of axon extension, positive regulation of axonogenesis, positive regulation of neuron differentiation, positive regulation of neurotrophin TRK receptor signaling pathway, positive regulation of protein autophosphorylation, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of stem cell proliferation, regulation of axonogenesis, regulation of neurotransmitter secretion, response to drug, response to electrical stimulus, response to glucocorticoid stimulus, response to lipopolysaccharide, response to mechanical stimulus, response to nicotine, response to ozone, response to peptide hormone stimulus, response to radiation, sensory perception of pain, small GTPase mediated signal transduction, transmembrane receptor protein tyrosine kinase signaling pathway Golgi lumen, endosome, extracellular region, extracellular space growth factor activity, nerve growth factor receptor binding, receptor signaling protein activity Human UniProtKB:Q99523 NGFR BHF-UCL UniProtKB {GO:0005515=PMID:21982860, GO:0010468=GO_REF:0000019, GO:0005886=Reactome:REACT_13785, GO:0031293=Reactome:REACT_13443, GO:0021675=GO_REF:0000019, GO:0048146=GO_REF:0000019, GO:0006886=GO_REF:0000024, GO:0005829=Reactome:REACT_13669, GO:0031069=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0004872=PMID:3022937, GO:0004871=PMID:3022937, GO:0031625=PMID:11279055, GO:0048011=Reactome:REACT_13776, GO:0043066=Reactome:REACT_13537, GO:0017137=GO_REF:0000024, GO:0009986=GO_REF:0000024, GO:0048406=GO_REF:0000019, GO:0006915=Reactome:REACT_13643, GO:0005576=Reactome:REACT_13658, GO:0006917=GO_REF:0000019, GO:0042593=GO_REF:0000024, GO:0045786=Reactome:REACT_13695, GO:0007417=GO_REF:0000019, GO:0097190=Reactome:REACT_13806, GO:0051799=GO_REF:0000019, GO:2001273=GO_REF:0000024, GO:0005887=PMID:3022937, GO:0040037=GO_REF:0000019, GO:0050771=Reactome:REACT_13815, GO:0005654=Reactome:REACT_13669, GO:0043588=GO_REF:0000019, GO:0016048=GO_REF:0000019, GO:0050772=Reactome:REACT_13779, GO:0050770=Reactome:REACT_13620, GO:0042488=GO_REF:0000019, GO:0005768=Reactome:REACT_13772, GO:0005035=GO_REF:0000019, GO:0004888=PMID:1846035} P08138 Tumor necrosis factor receptor superfamily member 16 protein 20101217 {GO:0005515=IPI, GO:0010468=IEA, GO:0005886=TAS, GO:0031293=TAS, GO:0021675=IEA, GO:0048146=IEA, GO:0006886=ISS, GO:0005829=TAS, GO:0031069=IEA, GO:0005737=IEA, GO:0007411=IEA, GO:0004872=TAS, GO:0004871=TAS, GO:0031625=IPI, GO:0048011=TAS, GO:0043066=TAS, GO:0017137=ISS, GO:0009986=ISS, GO:0048406=IEA, GO:0006915=TAS, GO:0005576=TAS, GO:0006917=IEA, GO:0042593=ISS, GO:0045786=TAS, GO:0007417=IEA, GO:0097190=TAS, GO:0051799=IEA, GO:2001273=ISS, GO:0005887=TAS, GO:0040037=IEA, GO:0050771=TAS, GO:0005654=TAS, GO:0043588=IEA, GO:0016048=IEA, GO:0050772=TAS, GO:0050770=TAS, GO:0042488=IEA, GO:0005768=TAS, GO:0005035=IEA, GO:0004888=TAS} apoptotic process, apoptotic signaling pathway, axon guidance, central nervous system development, detection of temperature stimulus, glucose homeostasis, hair follicle morphogenesis, induction of apoptosis, intracellular protein transport, membrane protein intracellular domain proteolysis, negative regulation of apoptotic process, negative regulation of axonogenesis, negative regulation of cell cycle, negative regulation of fibroblast growth factor receptor signaling pathway, negative regulation of hair follicle development, nerve development, neurotrophin TRK receptor signaling pathway, positive regulation of axonogenesis, positive regulation of fibroblast proliferation, positive regulation of odontogenesis of dentin-containing tooth, regulation of axonogenesis, regulation of gene expression, regulation of glucose import in response to insulin stimulus, skin development cell surface, cytoplasm, cytosol, endosome, extracellular region, integral to plasma membrane, nucleoplasm, plasma membrane Rab GTPase binding, death receptor activity, nerve growth factor binding, protein binding, receptor activity, signal transducer activity, transmembrane signaling receptor activity, ubiquitin protein ligase binding Human UniProtKB:Q9Z0W1 NGFRAP1 GOC UniProtKB {GO:0008625=GO_REF:0000019, GO:0048011=Reactome:REACT_13776, GO:0006919=Reactome:REACT_13533, GO:0006915=Reactome:REACT_13526, GO:0005634=GO_REF:0000039, GO:0007275=PMID:2171551, GO:0005123=GO_REF:0000019, GO:0006917=GO_REF:0000019, GO:0008656=Reactome:REACT_13533, GO:0097190=Reactome:REACT_13720, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_13657, GO:0005737=GO_REF:0000052} Q00994 Protein BEX3 protein 20130413 {GO:0008625=IEA, GO:0048011=TAS, GO:0006919=TAS, GO:0006915=TAS, GO:0005634=IEA, GO:0007275=TAS, GO:0005123=IEA, GO:0006917=IEA, GO:0008656=TAS, GO:0097190=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0005737=IDA} activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, apoptotic signaling pathway, extrinsic apoptotic signaling pathway via death domain receptors, induction of apoptosis, multicellular organismal development, neurotrophin TRK receptor signaling pathway cytoplasm, cytosol, nucleus cysteine-type endopeptidase activator activity involved in apoptotic process, death receptor binding, metal ion binding Human NGLY1 UniProtKB UniProtKB {GO:0005515=PMID:15358861, GO:0005737=PMID:15358861, GO:0006516=PMID:15358861, GO:0046872=GO_REF:0000037, GO:0000224=GO_REF:0000003} Q96IV0 Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase protein 20061201 {GO:0005515=IPI, GO:0005737=IDA, GO:0006516=IDA, GO:0046872=IEA, GO:0000224=IEA} glycoprotein catabolic process cytoplasm metal ion binding, peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity, protein binding Human UniProtKB:P54727 NGRN UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0030182=PMID:11118320, GO:0005634=PMID:11118320, GO:0005576=GO_REF:0000039} Q9NPE2 Neugrin protein 20011004 {GO:0003674=ND, GO:0030182=NAS, GO:0005634=NAS, GO:0005576=IEA} neuron differentiation extracellular region, nucleus molecular_function Human NHEJ1 IntAct UniProtKB {GO:0070419=PMID:20383123, GO:0005515=PMID:16439205, GO:0051351=PMID:16439205, GO:0030217=PMID:16439204, GO:0010212=PMID:16439205, GO:0030183=PMID:16439204, GO:0006310=GO_REF:0000002, GO:0005634=PMID:16439204, GO:0007417=PMID:16439204, GO:0006303=PMID:16439205, GO:0003677=GO_REF:0000037, GO:0006302=GO_REF:0000002} Q9H9Q4 Non-homologous end-joining factor 1 protein 20130415 {GO:0070419=IDA, GO:0005515=IPI, GO:0051351=NAS, GO:0030217=IMP, GO:0010212=IDA, GO:0030183=IMP, GO:0006310=IEA, GO:0005634=IDA, GO:0007417=NAS, GO:0006303=IMP, GO:0003677=IEA, GO:0006302=IEA} B cell differentiation, DNA recombination, T cell differentiation, central nervous system development, double-strand break repair, double-strand break repair via nonhomologous end joining, positive regulation of ligase activity, response to ionizing radiation nonhomologous end joining complex, nucleus DNA binding, protein binding Human UniProtKB:Q13426 NHLH1 PINC UniProtKB {GO:0006355=GO_REF:0000037, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0007417=PMID:1328219, GO:0003677=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q02575 Helix-loop-helix protein 1 protein 20030904 {GO:0006355=IEA, GO:0046983=IEA, GO:0005634=IEA, GO:0007417=TAS, GO:0003677=IEA, GO:0030154=IEA, GO:0006351=IEA} cell differentiation, central nervous system development, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, protein dimerization activity Human NHLH2 BHF-UCL UniProtKB {GO:0005515=PMID:22169038, GO:0001102=PMID:16314316, GO:0005667=PMID:16314316, GO:0051091=PMID:16314316, GO:0007617=GO_REF:0000019, GO:0045944=PMID:16314316, GO:0046983=GO_REF:0000002, GO:0042698=GO_REF:0000019, GO:0007417=PMID:1328219, GO:0003677=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q02577 Helix-loop-helix protein 2 protein 20111208 {GO:0005515=IPI, GO:0001102=IPI, GO:0005667=TAS, GO:0051091=TAS, GO:0007617=IEA, GO:0045944=TAS, GO:0046983=IEA, GO:0042698=IEA, GO:0007417=TAS, GO:0003677=IEA, GO:0030154=IEA, GO:0006351=IEA} cell differentiation, central nervous system development, mating behavior, ovulation cycle, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent transcription factor complex DNA binding, RNA polymerase II activating transcription factor binding, protein binding, protein dimerization activity Human UniProtKB:P25791 NHLRC1 UniProtKB UniProtKB {GO:0000209=PMID:15930137, GO:0005515=PMID:15930137, GO:0004842=PMID:15930137, GO:0048471=GO_REF:0000019, GO:0005783=GO_REF:0000039, GO:0031398=GO_REF:0000019, GO:0043161=PMID:15930137, GO:0005634=PMID:17908927, GO:0008270=GO_REF:0000002} Q6VVB1 E3 ubiquitin-protein ligase NHLRC1 protein 20100603 {GO:0000209=IDA, GO:0005515=IPI, GO:0004842=IDA, GO:0048471=IEA, GO:0005783=IEA, GO:0031398=IEA, GO:0043161=IDA, GO:0005634=IDA, GO:0008270=IEA} positive regulation of protein ubiquitination, proteasomal ubiquitin-dependent protein catabolic process, protein polyubiquitination endoplasmic reticulum, nucleus, perinuclear region of cytoplasm protein binding, ubiquitin-protein ligase activity, zinc ion binding Human NHLRC2 null null {} null null null null {} null null null NHLRC3 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q5JS37 NHL repeat-containing protein 3 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 NHP2 UniProtKB UniProtKB {GO:0030515=GO_REF:0000024, GO:0015030=GO_REF:0000039, GO:0003723=GO_REF:0000002, GO:0005730=GO_REF:0000039, GO:0005732=GO_REF:0000024, GO:0031118=GO_REF:0000024} Q9NX24 H/ACA ribonucleoprotein complex subunit 2 protein 20050712 {GO:0030515=ISS, GO:0015030=IEA, GO:0003723=IEA, GO:0005730=IEA, GO:0005732=ISS, GO:0031118=ISS} rRNA pseudouridine synthesis Cajal body, nucleolus, small nucleolar ribonucleoprotein complex RNA binding, snoRNA binding Human UniProtKB:P32495 NHP2L1 BHF-UCL UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:17412961, GO:0010467=Reactome:REACT_71, GO:0031428=PMID:17636026, GO:0003723=PMID:10593953, GO:0042254=GO_REF:0000002, GO:0005730=PMID:10593953, GO:0005634=PMID:8978773, GO:0030515=PMID:17636026, GO:0000398=Reactome:REACT_1753, GO:0030529=GO_REF:0000002, GO:0005681=GO_REF:0000037, GO:0005654=Reactome:REACT_2241} P55769 NHP2-like protein 1 protein 20091028 {GO:0008380=TAS, GO:0005515=IPI, GO:0010467=TAS, GO:0031428=NAS, GO:0003723=TAS, GO:0042254=IEA, GO:0005730=TAS, GO:0005634=TAS, GO:0030515=IDA, GO:0000398=TAS, GO:0030529=IEA, GO:0005681=IEA, GO:0005654=TAS} RNA splicing, gene expression, mRNA splicing, via spliceosome, ribosome biogenesis box C/D snoRNP complex, nucleolus, nucleoplasm, nucleus, ribonucleoprotein complex, spliceosomal complex RNA binding, protein binding, snoRNA binding Human UniProtKB:Q8WWY3 NHS UniProtKB UniProtKB {GO:0002088=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0030154=GO_REF:0000019} Q6T4R5 Nance-Horan syndrome protein protein 20130413 {GO:0002088=IEA, GO:0005634=IEA, GO:0030154=IEA} cell differentiation, lens development in camera-type eye nucleus Human UniProtKB-SubCell:SL-0191 NID1 BHF-UCL UniProtKB {GO:0031012=PMID:22261194, GO:0007160=GO_REF:0000019, GO:0043237=GO_REF:0000019, GO:0010811=GO_REF:0000019, GO:0005518=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0005605=GO_REF:0000019, GO:0032836=GO_REF:0000019, GO:0071944=GO_REF:0000019} P14543 Nidogen-1 protein 20120228 {GO:0031012=ISS, GO:0007160=IEA, GO:0043237=IEA, GO:0010811=IEA, GO:0005518=IEA, GO:0005509=IEA, GO:0005605=IEA, GO:0032836=IEA, GO:0071944=IEA} cell-matrix adhesion, glomerular basement membrane development, positive regulation of cell-substrate adhesion basal lamina, cell periphery, extracellular matrix calcium ion binding, collagen binding, laminin-1 binding colocalizes_with Human UniProtKB:F1RGY5 NID2 BHF-UCL UniProtKB {GO:0031012=PMID:22261194, GO:0005515=PMID:11956183, GO:0009986=GO_REF:0000019, GO:0007160=GO_REF:0000019, GO:0005518=PMID:9733643, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000038, GO:0007155=PMID:9733643, GO:0005604=GO_REF:0000039} Q14112 Nidogen-2 protein 20120228 {GO:0031012=ISS, GO:0005515=IPI, GO:0009986=IEA, GO:0007160=IEA, GO:0005518=TAS, GO:0005509=IEA, GO:0016021=IEA, GO:0007155=TAS, GO:0005604=IEA} cell adhesion, cell-matrix adhesion basement membrane, cell surface, extracellular matrix, integral to membrane calcium ion binding, collagen binding, protein binding colocalizes_with Human UniProtKB:F1SFF3 NIF3L1 BHF-UCL UniProtKB {GO:0005515=PMID:19060904, GO:0005739=GO_REF:0000019, GO:0005737=PMID:15163635, GO:0045893=PMID:15163635, GO:0008134=PMID:15163635} Q9GZT8 NIF3-like protein 1 protein 20080307 {GO:0005515=IPI, GO:0005739=IEA, GO:0005737=IDA, GO:0045893=IDA, GO:0008134=IPI} positive regulation of transcription, DNA-dependent cytoplasm, mitochondrion protein binding, transcription factor binding Human UniProtKB:Q99MZ3 NIN IntAct UniProtKB {GO:0005515=PMID:15147888, GO:0051642=PMID:16154161, GO:0005813=PMID:12927815, GO:0090222=GO_REF:0000019, GO:0005814=GO_REF:0000019, GO:0005874=GO_REF:0000037, GO:0005509=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0034454=GO_REF:0000019} Q8N4C6 Ninein protein 20130415 {GO:0005515=IPI, GO:0051642=TAS, GO:0005813=IDA, GO:0090222=IEA, GO:0005814=IEA, GO:0005874=IEA, GO:0005509=IEA, GO:0005525=IEA, GO:0034454=IEA} centrosome localization, centrosome-templated microtubule nucleation, microtubule anchoring at centrosome centriole, centrosome, microtubule GTP binding, calcium ion binding, protein binding Human UniProtKB:P49841 NINJ1 PINC UniProtKB {GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037, GO:0042246=GO_REF:0000002, GO:0007399=PMID:9261151} Q92982 Ninjurin-1 protein 20030904 {GO:0016021=IEA, GO:0007155=IEA, GO:0042246=IEA, GO:0007399=TAS} cell adhesion, nervous system development, tissue regeneration integral to membrane Human NINL Reactome UniProtKB {GO:0005815=GO_REF:0000039, GO:0000086=Reactome:REACT_2203, GO:0005874=GO_REF:0000037, GO:0005509=GO_REF:0000002, GO:0000278=Reactome:REACT_152, GO:0005829=Reactome:REACT_15470} Q9Y2I6 Ninein-like protein protein 20130213 {GO:0005815=IEA, GO:0000086=TAS, GO:0005874=IEA, GO:0005509=IEA, GO:0000278=TAS, GO:0005829=TAS} G2/M transition of mitotic cell cycle, mitotic cell cycle cytosol, microtubule, microtubule organizing center calcium ion binding Human NIP7 UniProtKB UniProtKB {GO:0005515=PMID:17643419, GO:0042255=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0005634=GO_REF:0000002} Q9Y221 60S ribosome subunit biogenesis protein NIP7 homolog protein 20080624 {GO:0005515=IPI, GO:0042255=IEA, GO:0003723=IEA, GO:0005730=IEA, GO:0005634=IEA} ribosome assembly nucleolus, nucleus RNA binding, protein binding Human UniProtKB:Q9Y3A5 NIPA2 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0015095=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005769=GO_REF:0000039} Q8N8Q9 Magnesium transporter NIPA2 protein 20130413 {GO:0005886=IEA, GO:0015095=IEA, GO:0016021=IEA, GO:0005769=IEA} early endosome, integral to membrane, plasma membrane magnesium ion transmembrane transporter activity Human UniProtKB-SubCell:SL-0039 NIPAL3 UniProtKB UniProtKB {GO:0016020=GO_REF:0000002, GO:0015095=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q6P499 NIPA-like protein 3 protein 20130413 {GO:0016020=IEA, GO:0015095=IEA, GO:0016021=IEA} integral to membrane, membrane magnesium ion transmembrane transporter activity Human UniProtKB-KW:KW-0812 NIPBL BHF-UCL UniProtKB {GO:0001656=PMID:15146185, GO:0005515=PMID:16682347, GO:0035136=PMID:15146186, GO:0042826=PMID:18854353, GO:0070087=PMID:15882967, GO:0007605=PMID:15146186, GO:0048592=PMID:8291537, GO:0005634=PMID:16802858, GO:0071481=PMID:17468178, GO:0048703=GO_REF:0000019, GO:0045778=GO_REF:0000019, GO:0035261=PMID:19242925, GO:0000910=Reactome:REACT_1932, GO:0048589=PMID:15146186, GO:0000087=Reactome:REACT_910, GO:0045444=GO_REF:0000019, GO:0040018=GO_REF:0000019, GO:0042471=PMID:8291537, GO:0042634=PMID:15146186, GO:0000122=PMID:18854353, GO:0032116=PMID:16682347, GO:0008022=PMID:17577209, GO:0003151=PMID:19242925, GO:0006974=PMID:17468178, GO:0045995=PMID:19242925, GO:0003007=PMID:8291537, GO:0047485=PMID:16802858, GO:0031065=PMID:18854353, GO:0048557=PMID:19242925, GO:0060325=PMID:19242925, GO:0050890=PMID:15146186, GO:0007420=PMID:8291537, GO:0036033=GO_REF:0000019, GO:0061038=PMID:19242925, GO:0048638=PMID:19242925, GO:0019827=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0061010=PMID:19242925, GO:0034088=PMID:16682347, GO:0005654=Reactome:REACT_150390, GO:0035115=PMID:19242925, GO:0034613=PMID:17468178, GO:0000278=Reactome:REACT_152, GO:0045892=PMID:18854353, GO:0007064=PMID:16100726} Q6KC79 Nipped-B-like protein protein 20100127 {GO:0001656=NAS, GO:0005515=IPI, GO:0035136=IMP, GO:0042826=IPI, GO:0070087=IPI, GO:0007605=IMP, GO:0048592=IMP, GO:0005634=IDA, GO:0071481=IMP, GO:0048703=IEA, GO:0045778=IEA, GO:0035261=IMP, GO:0000910=TAS, GO:0048589=IMP, GO:0000087=TAS, GO:0045444=IEA, GO:0040018=IEA, GO:0042471=IMP, GO:0042634=IMP, GO:0000122=IDA, GO:0032116=IDA, GO:0008022=IPI, GO:0003151=IMP, GO:0006974=IMP, GO:0045995=IMP, GO:0003007=IMP, GO:0047485=IPI, GO:0031065=IDA, GO:0048557=IMP, GO:0060325=IMP, GO:0050890=IMP, GO:0007420=IMP, GO:0036033=IEA, GO:0061038=IMP, GO:0048638=IMP, GO:0019827=IEA, GO:0003682=IEA, GO:0061010=IMP, GO:0034088=IMP, GO:0005654=TAS, GO:0035115=IMP, GO:0034613=IMP, GO:0000278=TAS, GO:0045892=IDA, GO:0007064=IMP} M phase of mitotic cell cycle, brain development, cellular protein localization, cellular response to X-ray, cognition, cytokinesis, developmental growth, ear morphogenesis, embryonic digestive tract morphogenesis, embryonic forelimb morphogenesis, embryonic viscerocranium morphogenesis, external genitalia morphogenesis, eye morphogenesis, face morphogenesis, fat cell differentiation, forelimb morphogenesis, gall bladder development, heart morphogenesis, maintenance of mitotic sister chromatid cohesion, metanephros development, mitotic cell cycle, mitotic sister chromatid cohesion, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, outflow tract morphogenesis, positive regulation of histone deacetylation, positive regulation of multicellular organism growth, positive regulation of ossification, regulation of developmental growth, regulation of embryonic development, regulation of hair cycle, response to DNA damage stimulus, sensory perception of sound, stem cell maintenance, uterus morphogenesis SMC loading complex, nucleoplasm, nucleus chromatin binding, chromo shadow domain binding, histone deacetylase binding, mediator complex binding, protein C-terminus binding, protein N-terminus binding, protein binding Human NIPSNAP1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000024, GO:0097060=GO_REF:0000019, GO:0005743=GO_REF:0000019, GO:0042165=GO_REF:0000019, GO:0019233=GO_REF:0000019} Q9BPW8 Protein NipSnap homolog 1 protein 20041006 {GO:0005739=ISS, GO:0097060=IEA, GO:0005743=IEA, GO:0042165=IEA, GO:0019233=IEA} sensory perception of pain mitochondrial inner membrane, mitochondrion, synaptic membrane neurotransmitter binding Human UniProtKB:O55125 NIPSNAP3A IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0005829=GO_REF:0000039} Q9UFN0 Protein NipSnap homolog 3A protein 20130415 {GO:0005515=IPI, GO:0005829=IEA} cytosol protein binding Human UniProtKB:Q9H3D4 NISCH BHF-UCL UniProtKB {GO:0030336=GO_REF:0000019, GO:0030036=GO_REF:0000019, GO:0005886=PMID:15028622, GO:0006915=GO_REF:0000037, GO:0005829=PMID:15028622, GO:0016601=GO_REF:0000019, GO:0007154=GO_REF:0000002, GO:0005178=GO_REF:0000019, GO:0032228=GO_REF:0000019, GO:0008217=GO_REF:0000019, GO:0006006=GO_REF:0000019, GO:0055037=GO_REF:0000039, GO:0035091=GO_REF:0000002, GO:0008227=GO_REF:0000019, GO:0048243=GO_REF:0000019, GO:0005769=GO_REF:0000039} Q9Y2I1 Nischarin protein 20100628 {GO:0030336=IEA, GO:0030036=IEA, GO:0005886=IDA, GO:0006915=IEA, GO:0005829=IDA, GO:0016601=IEA, GO:0007154=IEA, GO:0005178=IEA, GO:0032228=IEA, GO:0008217=IEA, GO:0006006=IEA, GO:0055037=IEA, GO:0035091=IEA, GO:0008227=IEA, GO:0048243=IEA, GO:0005769=IEA} Rac protein signal transduction, actin cytoskeleton organization, apoptotic process, cell communication, glucose metabolic process, negative regulation of cell migration, norepinephrine secretion, regulation of blood pressure, regulation of synaptic transmission, GABAergic cytosol, early endosome, plasma membrane, recycling endosome G-protein coupled amine receptor activity, integrin binding, phosphatidylinositol binding Human NIT1 PINC UniProtKB {GO:0005739=GO_REF:0000039, GO:0008150=GO_REF:0000015, GO:0006807=GO_REF:0000002, GO:0000257=PMID:9671749, GO:0016810=GO_REF:0000002} Q86X76 Nitrilase homolog 1 protein 20050308 {GO:0005739=IEA, GO:0008150=ND, GO:0006807=IEA, GO:0000257=TAS, GO:0016810=IEA} biological_process, nitrogen compound metabolic process mitochondrion hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, nitrilase activity Human NIT2 HPA UniProtKB {GO:0005739=GO_REF:0000019, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0006807=GO_REF:0000002, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0016810=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0050152=GO_REF:0000003} Q9NQR4 Omega-amidase NIT2 protein 20110516 {GO:0005739=IEA, GO:0003674=ND, GO:0008150=ND, GO:0006807=IEA, GO:0005813=IDA, GO:0005737=IDA, GO:0016810=IEA, GO:0005575=ND, GO:0050152=IEA} biological_process, nitrogen compound metabolic process cellular_component, centrosome, cytoplasm, mitochondrion hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, molecular_function, omega-amidase activity Human NKAP HPA UniProtKB {GO:0046638=PMID:19409814, GO:0005515=PMID:19409814, GO:0033077=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000122=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0031490=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0071425=GO_REF:0000019, GO:0007219=GO_REF:0000037, GO:0019827=GO_REF:0000019, GO:0003682=PMID:19409814, GO:0030851=GO_REF:0000019, GO:0045892=PMID:19409814} Q8N5F7 NF-kappa-B-activating protein protein 20080818 {GO:0046638=IMP, GO:0005515=IPI, GO:0033077=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0000122=IEA, GO:0006351=IEA, GO:0031490=IEA, GO:0005737=IDA, GO:0071425=IEA, GO:0007219=IEA, GO:0019827=IEA, GO:0003682=IDA, GO:0030851=IEA, GO:0045892=IDA} Notch signaling pathway, T cell differentiation in thymus, granulocyte differentiation, hematopoietic stem cell proliferation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of alpha-beta T cell differentiation, stem cell maintenance, transcription, DNA-dependent cytoplasm, nucleolus, nucleus chromatin DNA binding, chromatin binding, protein binding Human NKAPL null null {} null null null null {} null null null NKD1 BHF-UCL UniProtKB {GO:0005515=PMID:16567647, GO:0001754=PMID:15687260, GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:1901233=GO_REF:0000024, GO:2000096=GO_REF:0000024, GO:1901231=GO_REF:0000024, GO:0090249=PMID:15687260, GO:0030165=GO_REF:0000019, GO:0007525=PMID:15687260, GO:0005737=GO_REF:0000039, GO:0016055=GO_REF:0000037, GO:0090090=GO_REF:0000024} Q969G9 Protein naked cuticle homolog 1 protein 20120807 {GO:0005515=IPI, GO:0001754=ISS, GO:0005886=IEA, GO:0005509=IEA, GO:1901233=ISS, GO:2000096=ISS, GO:1901231=ISS, GO:0090249=ISS, GO:0030165=IEA, GO:0007525=ISS, GO:0005737=IEA, GO:0016055=IEA, GO:0090090=ISS} Wnt receptor signaling pathway, eye photoreceptor cell differentiation, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of convergent extension involved in axis elongation, positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway, positive regulation of non-canonical Wnt receptor signaling pathway via JNK cascade, regulation of cell motility involved in somitogenic axis elongation, somatic muscle development cytoplasm, plasma membrane PDZ domain binding, calcium ion binding, protein binding Human UniProtKB:F6V4I1 NKD2 BHF-UCL UniProtKB {GO:0005515=PMID:15687260, GO:0005509=GO_REF:0000002, GO:0031410=PMID:15064403, GO:0006887=GO_REF:0000037, GO:0016328=PMID:20177058, GO:0071944=PMID:15064403, GO:0016323=PMID:17553928, GO:0019838=PMID:15064403, GO:0048210=PMID:17553928, GO:0016023=GO_REF:0000039, GO:0016055=GO_REF:0000037, GO:0090090=PMID:20177058, GO:0031625=PMID:18757723} Q969F2 Protein naked cuticle homolog 2 protein 20120806 {GO:0005515=IPI, GO:0005509=IEA, GO:0031410=IDA, GO:0006887=IEA, GO:0016328=IDA, GO:0071944=IDA, GO:0016323=IDA, GO:0019838=IPI, GO:0048210=IMP, GO:0016023=IEA, GO:0016055=IEA, GO:0090090=IDA, GO:0031625=IPI} Golgi vesicle fusion to target membrane, Wnt receptor signaling pathway, exocytosis, negative regulation of canonical Wnt receptor signaling pathway basolateral plasma membrane, cell periphery, cytoplasmic membrane-bounded vesicle, cytoplasmic vesicle, lateral plasma membrane calcium ion binding, growth factor binding, protein binding, ubiquitin protein ligase binding Human NKG7 PINC UniProtKB {GO:0016020=GO_REF:0000002, GO:0005887=PMID:8458737, GO:0016021=GO_REF:0000002} Q16617 Protein NKG7 protein 20030904 {GO:0016020=IEA, GO:0005887=TAS, GO:0016021=IEA} integral to membrane, integral to plasma membrane, membrane Human NKIRAS1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0007249=PMID:10657303, GO:0003924=PMID:10657303, GO:0005575=GO_REF:0000015, GO:0005525=GO_REF:0000037} Q9NYS0 NF-kappa-B inhibitor-interacting Ras-like protein 1 protein 20010823 {GO:0005737=IEA, GO:0016020=IEA, GO:0007264=IEA, GO:0007249=NAS, GO:0003924=NAS, GO:0005575=ND, GO:0005525=IEA} I-kappaB kinase/NF-kappaB cascade, small GTPase mediated signal transduction cellular_component, cytoplasm, membrane GTP binding, GTPase activity Human NKIRAS2 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0007249=PMID:10657303, GO:0003924=PMID:10657303, GO:0005575=GO_REF:0000015, GO:0005525=GO_REF:0000037} Q9NYR9 NF-kappa-B inhibitor-interacting Ras-like protein 2 protein 20061026 {GO:0005622=IEA, GO:0005737=IEA, GO:0016020=IEA, GO:0007264=IEA, GO:0007249=NAS, GO:0003924=NAS, GO:0005575=ND, GO:0005525=IEA} I-kappaB kinase/NF-kappaB cascade, small GTPase mediated signal transduction cellular_component, cytoplasm, intracellular, membrane GTP binding, GTPase activity Human NKRF IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0003725=GO_REF:0000002, GO:0005730=GO_REF:0000039, GO:0005634=PMID:10562553, GO:0045892=PMID:10562553, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O15226 NF-kappa-B-repressing factor protein 20130415 {GO:0005515=IPI, GO:0003725=IEA, GO:0005730=IEA, GO:0005634=IDA, GO:0045892=IDA, GO:0003677=IEA, GO:0006351=IEA} negative regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus, nucleus DNA binding, double-stranded RNA binding, protein binding Human UniProtKB:Q96C10 NKTR PINC UniProtKB {GO:0016018=PMID:8421688, GO:0016020=GO_REF:0000039, GO:0006457=GO_REF:0000037, GO:0003755=GO_REF:0000003} P30414 NK-tumor recognition protein protein 20030904 {GO:0016018=TAS, GO:0016020=IEA, GO:0006457=IEA, GO:0003755=IEA} protein folding membrane cyclosporin A binding, peptidyl-prolyl cis-trans isomerase activity Human NKX1-1 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0008150=GO_REF:0000015, GO:0043467=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0050877=GO_REF:0000019, GO:0005634=GO_REF:0000029, GO:0003677=GO_REF:0000029} Q15270 NK1 transcription factor-related protein 1 protein 20061026 {GO:0043565=IEA, GO:0008150=ND, GO:0043467=IEA, GO:0003700=IEA, GO:0050877=IEA, GO:0005634=NAS, GO:0003677=NAS} biological_process, neurological system process, regulation of generation of precursor metabolites and energy nucleus DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human NKX2-1 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0003700=PMID:7559607, GO:0044212=PMID:7559607, GO:0030324=PMID:15494458, GO:0048709=GO_REF:0000019, GO:0003705=GO_REF:0000019, GO:0021983=GO_REF:0000019, GO:0030878=PMID:15494458, GO:0010719=PMID:19293183, GO:0031128=GO_REF:0000019, GO:0042696=GO_REF:0000019, GO:0060430=GO_REF:0000019, GO:0021795=GO_REF:0000019, GO:0048646=GO_REF:0000019, GO:0021798=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0045944=PMID:7559607, GO:0007626=GO_REF:0000019, GO:0009725=PMID:16960125, GO:0021892=GO_REF:0000019, GO:0030512=PMID:19293183, GO:0005667=GO_REF:0000019, GO:0030336=PMID:19293183, GO:0021877=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0003677=PMID:7635972, GO:0043565=GO_REF:0000019, GO:0021766=GO_REF:0000019, GO:0060441=PMID:8675988, GO:0007492=GO_REF:0000019, GO:0007420=PMID:11971878, GO:0033327=GO_REF:0000019, GO:0060486=GO_REF:0000019, GO:0005654=GO_REF:0000024, GO:0030900=PMID:15494458, GO:0060510=GO_REF:0000019, GO:0021759=PMID:11854319, GO:0001764=GO_REF:0000019, GO:0045893=PMID:14960358, GO:0006644=GO_REF:0000019} P43699 Homeobox protein Nkx-2.1 protein 20130415 {GO:0005515=IPI, GO:0003700=IDA, GO:0044212=IDA, GO:0030324=IEP, GO:0048709=IEA, GO:0003705=IEA, GO:0021983=IEA, GO:0030878=IEP, GO:0010719=IDA, GO:0031128=IEA, GO:0042696=IEA, GO:0060430=IEA, GO:0021795=IEA, GO:0048646=IEA, GO:0021798=IEA, GO:0007411=IEA, GO:0045944=IDA, GO:0007626=IEA, GO:0009725=IEP, GO:0021892=IEA, GO:0030512=IDA, GO:0005667=IEA, GO:0030336=IDA, GO:0021877=IEA, GO:0000122=IEA, GO:0003677=IMP, GO:0043565=IEA, GO:0021766=IEA, GO:0060441=IEP, GO:0007492=IEA, GO:0007420=IMP, GO:0033327=IEA, GO:0060486=IEA, GO:0005654=ISS, GO:0030900=IEP, GO:0060510=IEA, GO:0021759=IMP, GO:0001764=IEA, GO:0045893=IDA, GO:0006644=IEA} Clara cell differentiation, Leydig cell differentiation, Type II pneumocyte differentiation, anatomical structure formation involved in morphogenesis, axon guidance, brain development, cerebral cortex GABAergic interneuron differentiation, cerebral cortex cell migration, developmental induction, endoderm development, epithelial tube branching involved in lung morphogenesis, forebrain development, forebrain dorsal/ventral pattern formation, forebrain neuron fate commitment, globus pallidus development, hippocampus development, locomotory behavior, lung development, lung saccule development, menarche, negative regulation of cell migration, negative regulation of epithelial to mesenchymal transition, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transforming growth factor beta receptor signaling pathway, neuron migration, oligodendrocyte differentiation, phospholipid metabolic process, pituitary gland development, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, response to hormone stimulus, thyroid gland development nucleoplasm, transcription factor complex DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding Human UniProtKB:P16333 NKX2-2 Reactome UniProtKB {GO:0003700=GO_REF:0000019, GO:0021530=GO_REF:0000019, GO:0048708=GO_REF:0000019, GO:0007224=GO_REF:0000019, GO:0003326=GO_REF:0000019, GO:0003327=GO_REF:0000019, GO:0051091=GO_REF:0000024, GO:0045944=GO_REF:0000019, GO:0003329=GO_REF:0000019, GO:0021522=GO_REF:0000019, GO:0003713=GO_REF:0000024, GO:0048665=GO_REF:0000019, GO:0003323=GO_REF:0000019, GO:0048565=GO_REF:0000019, GO:0060580=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000019, GO:0045665=GO_REF:0000019, GO:0045666=GO_REF:0000019, GO:0007420=PMID:1346742, GO:0031018=Reactome:REACT_13698, GO:0014003=GO_REF:0000019, GO:0048714=GO_REF:0000019, GO:0003682=GO_REF:0000024, GO:0005654=Reactome:REACT_13545, GO:0001159=GO_REF:0000024, GO:0008134=GO_REF:0000019} O95096 Homeobox protein Nkx-2.2 protein 20130301 {GO:0003700=IEA, GO:0021530=IEA, GO:0048708=IEA, GO:0007224=IEA, GO:0003326=IEA, GO:0003327=IEA, GO:0051091=ISS, GO:0045944=IEA, GO:0003329=IEA, GO:0021522=IEA, GO:0003713=ISS, GO:0048665=IEA, GO:0003323=IEA, GO:0048565=IEA, GO:0060580=IEA, GO:0006351=IEA, GO:0043565=IEA, GO:0045665=IEA, GO:0045666=IEA, GO:0007420=TAS, GO:0031018=TAS, GO:0014003=IEA, GO:0048714=IEA, GO:0003682=ISS, GO:0005654=TAS, GO:0001159=ISS, GO:0008134=IEA} astrocyte differentiation, brain development, digestive tract development, endocrine pancreas development, negative regulation of neuron differentiation, neuron fate specification, oligodendrocyte development, pancreatic A cell fate commitment, pancreatic PP cell fate commitment, positive regulation of neuron differentiation, positive regulation of oligodendrocyte differentiation, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, smoothened signaling pathway, spinal cord motor neuron differentiation, spinal cord oligodendrocyte cell fate specification, transcription, DNA-dependent, type B pancreatic cell development, type B pancreatic cell fate commitment, ventral spinal cord interneuron fate determination nucleoplasm chromatin binding, core promoter proximal region DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, transcription factor binding Human NKX2-3 UniProtKB UniProtKB {GO:0048621=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0043367=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0050900=GO_REF:0000019, GO:0048536=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0048535=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0048541=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0002317=GO_REF:0000019, GO:0030225=GO_REF:0000019, GO:0042475=GO_REF:0000019, GO:0006641=GO_REF:0000019, GO:0022612=GO_REF:0000019, GO:0001776=GO_REF:0000019} Q8TAU0 Homeobox protein Nkx-2.3 protein 20090316 {GO:0048621=IEA, GO:0003700=IEA, GO:0043367=IEA, GO:0005634=IEA, GO:0005575=ND, GO:0050900=IEA, GO:0048536=IEA, GO:0006351=IEA, GO:0048535=IEA, GO:0043565=IEA, GO:0003674=ND, GO:0008150=ND, GO:0048541=IEA, GO:0042127=IEA, GO:0045944=IEA, GO:0002317=IEA, GO:0030225=IEA, GO:0042475=IEA, GO:0006641=IEA, GO:0022612=IEA, GO:0001776=IEA} CD4-positive, alpha-beta T cell differentiation, Peyer's patch development, biological_process, gland morphogenesis, leukocyte homeostasis, leukocyte migration, lymph node development, macrophage differentiation, odontogenesis of dentin-containing tooth, plasma cell differentiation, positive regulation of transcription from RNA polymerase II promoter, post-embryonic digestive tract morphogenesis, regulation of cell proliferation, spleen development, transcription, DNA-dependent, triglyceride metabolic process cellular_component, nucleus molecular_function, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human NKX2-5 BHF-UCL UniProtKB {GO:0005515=PMID:18579533, GO:0003700=PMID:9312027, GO:0001190=GO_REF:0000019, GO:0044212=PMID:19479054, GO:0003285=PMID:10587520, GO:0060043=GO_REF:0000019, GO:0003705=GO_REF:0000019, GO:0003350=GO_REF:0000019, GO:0010736=PMID:8900537, GO:0010735=PMID:8900537, GO:0030878=PMID:16418214, GO:0010832=PMID:15653675, GO:0048536=PMID:8900537, GO:0060048=GO_REF:0000019, GO:0030154=PMID:8900537, GO:0042803=GO_REF:0000019, GO:0007512=PMID:9651244, GO:0001947=PMID:8900537, GO:0010765=PMID:8900537, GO:0010667=PMID:11889119, GO:0055005=GO_REF:0000019, GO:0055007=PMID:8900537, GO:0055008=PMID:11889119, GO:0045823=GO_REF:0000024, GO:0003278=GO_REF:0000019, GO:0001104=GO_REF:0000019, GO:0046982=PMID:8900537, GO:1901387=PMID:8900537, GO:0045214=GO_REF:0000019, GO:0030509=GO_REF:0000019, GO:0000122=PMID:8900537, GO:0060038=GO_REF:0000019, GO:0060037=PMID:8900537, GO:0060347=GO_REF:0000019, GO:0060928=GO_REF:0000019, GO:0060929=GO_REF:0000019, GO:0055117=PMID:8900537, GO:0055015=PMID:8900537, GO:0055014=PMID:8900537, GO:0045893=PMID:18079734, GO:0045892=PMID:8900537, GO:0008134=PMID:9858576, GO:0008284=PMID:8900537, GO:0003161=PMID:15109497, GO:0003166=GO_REF:0000019, GO:0003168=GO_REF:0000019, GO:0005634=PMID:9858576, GO:0051891=PMID:8900537, GO:0060261=PMID:8900537, GO:0005737=GO_REF:0000019, GO:0045944=PMID:8900537, GO:0003221=PMID:20807224, GO:0003222=GO_REF:0000019, GO:0060971=GO_REF:0000019, GO:0060070=GO_REF:0000019, GO:0090090=GO_REF:0000024, GO:0030097=PMID:8900537, GO:0005667=PMID:9312027, GO:0043066=PMID:8900537, GO:0035050=PMID:8900537, GO:0060413=PMID:10587520, GO:0060412=PMID:20807224, GO:0003342=GO_REF:0000019, GO:0003677=PMID:9858576, GO:0043565=PMID:10948187, GO:0003007=PMID:8900537, GO:0045666=PMID:15653675, GO:0003211=GO_REF:0000019, GO:0003682=PMID:16678093, GO:0003148=PMID:20807224, GO:0001570=PMID:8900537} P52952 Homeobox protein Nkx-2.5 protein 20081128 {GO:0005515=IPI, GO:0003700=IDA, GO:0001190=IEA, GO:0044212=IDA, GO:0003285=IMP, GO:0060043=IEA, GO:0003705=IEA, GO:0003350=IEA, GO:0010736=ISS, GO:0010735=ISS, GO:0030878=IMP, GO:0010832=IMP, GO:0048536=ISS, GO:0060048=IEA, GO:0030154=ISS, GO:0042803=IEA, GO:0007512=IMP, GO:0001947=ISS, GO:0010765=ISS, GO:0010667=IMP, GO:0055005=IEA, GO:0055007=ISS, GO:0055008=IMP, GO:0045823=ISS, GO:0003278=IEA, GO:0001104=IEA, GO:0046982=ISS, GO:1901387=ISS, GO:0045214=IEA, GO:0030509=IEA, GO:0000122=ISS, GO:0060038=IEA, GO:0060037=ISS, GO:0060347=IEA, GO:0060928=IEA, GO:0060929=IEA, GO:0055117=ISS, GO:0055015=ISS, GO:0055014=ISS, GO:0045893=IMP, GO:0045892=ISS, GO:0008134=IPI, GO:0008284=ISS, GO:0003161=IMP, GO:0003166=IEA, GO:0003168=IEA, GO:0005634=IDA, GO:0051891=ISS, GO:0060261=ISS, GO:0005737=IEA, GO:0045944=ISS, GO:0003221=IMP, GO:0003222=IEA, GO:0060971=IEA, GO:0060070=IEA, GO:0090090=ISS, GO:0030097=ISS, GO:0005667=IC, GO:0043066=ISS, GO:0035050=ISS, GO:0060413=IMP, GO:0060412=IMP, GO:0003342=IEA, GO:0003677=IDA, GO:0043565=IDA, GO:0003007=ISS, GO:0045666=IMP, GO:0003211=IEA, GO:0003682=IDA, GO:0003148=IMP, GO:0001570=ISS} BMP signaling pathway, Purkinje myocyte differentiation, adult heart development, apoptotic process involved in heart morphogenesis, atrial cardiac muscle cell development, atrial septum morphogenesis, atrioventricular node cell development, atrioventricular node cell fate commitment, bundle of His development, canonical Wnt receptor signaling pathway, cardiac conduction system development, cardiac muscle cell differentiation, cardiac muscle cell proliferation, cardiac muscle contraction, cardiac muscle tissue morphogenesis, cardiac ventricle formation, cell differentiation, embryonic heart tube development, embryonic heart tube left/right pattern formation, heart looping, heart morphogenesis, heart trabecula formation, hemopoiesis, negative regulation of apoptotic process, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cardiac muscle cell apoptotic process, negative regulation of myotube differentiation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, outflow tract septum morphogenesis, pharyngeal system development, positive regulation of cardioblast differentiation, positive regulation of cell proliferation, positive regulation of heart contraction, positive regulation of neuron differentiation, positive regulation of sodium ion transport, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription initiation from RNA polymerase II promoter, positive regulation of transcription via serum response element binding, positive regulation of transcription, DNA-dependent, positive regulation of voltage-gated calcium channel activity, proepicardium development, pulmonary myocardium development, regulation of cardiac muscle cell proliferation, regulation of cardiac muscle contraction, right ventricular cardiac muscle tissue morphogenesis, sarcomere organization, septum secundum development, spleen development, thyroid gland development, vasculogenesis, ventricular cardiac muscle cell development, ventricular cardiac myofibril development, ventricular septum morphogenesis, ventricular trabecula myocardium morphogenesis cytoplasm, nucleus, transcription factor complex DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, RNA polymerase II transcription cofactor activity, RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription, chromatin binding, protein binding, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, serum response element binding, transcription factor binding, transcription regulatory region DNA binding Human UniProtKB:P42582 NKX3-1 GOC UniProtKB {GO:0005515=PMID:18296735, GO:0001656=GO_REF:0000019, GO:0004882=PMID:19886863, GO:0003700=PMID:20855495, GO:0000983=GO_REF:0000019, GO:0044212=PMID:19263243, GO:0001756=GO_REF:0000019, GO:2001022=PMID:20395202, GO:0050680=GO_REF:0000024, GO:0043621=PMID:19780584, GO:0007507=GO_REF:0000019, GO:0005622=PMID:19597465, GO:0045860=PMID:20395202, GO:0071356=PMID:18757402, GO:0051781=PMID:20855495, GO:0010942=PMID:19266349, GO:0000976=PMID:20855495, GO:0030331=PMID:18794125, GO:0007275=PMID:9537602, GO:2001244=PMID:17486276, GO:0014068=PMID:20395202, GO:0008656=PMID:19266349, GO:0060037=GO_REF:0000019, GO:0060442=GO_REF:0000024, GO:0045931=PMID:20855495, GO:0045930=PMID:19266349, GO:0071383=PMID:19886863, GO:0071347=PMID:18757402, GO:0043491=PMID:19597465, GO:0045893=GO_REF:0000024, GO:0045892=PMID:18794125, GO:0008134=PMID:20716579, GO:0060770=GO_REF:0000024, GO:2000836=PMID:19886863, GO:0008285=PMID:19266349, GO:0097162=GO_REF:0000019, GO:0042826=PMID:18974119, GO:2001235=PMID:20599703, GO:0030284=PMID:18794125, GO:0005634=PMID:20855495, GO:0060664=GO_REF:0000024, GO:0045944=PMID:20855495, GO:0007431=GO_REF:0000024, GO:0006355=PMID:11137288, GO:0006919=PMID:19266349, GO:0071456=PMID:21056661, GO:0035907=GO_REF:0000019, GO:0033574=GO_REF:0000024, GO:0043565=PMID:19780584, GO:0071850=PMID:19266349, GO:0071899=PMID:18794125, GO:0043569=GO_REF:0000024, GO:0048754=GO_REF:0000024, GO:0008584=GO_REF:0000019, GO:0030521=PMID:19886863} Q99801 Homeobox protein Nkx-3.1 protein 20130413 {GO:0005515=IPI, GO:0001656=IEA, GO:0004882=IDA, GO:0003700=IDA, GO:0000983=IEA, GO:0044212=IDA, GO:0001756=IEA, GO:2001022=IDA, GO:0050680=ISS, GO:0043621=IDA, GO:0007507=IEA, GO:0005622=IDA, GO:0045860=IDA, GO:0071356=IEP, GO:0051781=IMP, GO:0010942=IDA, GO:0000976=IDA, GO:0030331=IDA, GO:0007275=TAS, GO:2001244=IDA, GO:0014068=IDA, GO:0008656=IDA, GO:0060037=IEA, GO:0060442=ISS, GO:0045931=IMP, GO:0045930=IDA, GO:0071383=IDA, GO:0071347=IEP, GO:0043491=IMP, GO:0045893=ISS, GO:0045892=IDA, GO:0008134=IPI, GO:0060770=ISS, GO:2000836=IDA, GO:0008285=IDA, GO:0097162=IEA, GO:0042826=IPI, GO:2001235=IDA, GO:0030284=IDA, GO:0005634=IC, GO:0060664=ISS, GO:0045944=IDA, GO:0007431=ISS, GO:0006355=NAS, GO:0006919=IDA, GO:0071456=IDA, GO:0035907=IEA, GO:0033574=ISS, GO:0043565=IDA, GO:0071850=IDA, GO:0071899=IDA, GO:0043569=ISS, GO:0048754=ISS, GO:0008584=IEA, GO:0030521=IDA} activation of cysteine-type endopeptidase activity involved in apoptotic process, androgen receptor signaling pathway, branching involved in prostate gland morphogenesis, branching morphogenesis of an epithelial tube, cellular response to hypoxia, cellular response to interleukin-1, cellular response to steroid hormone stimulus, cellular response to tumor necrosis factor, dorsal aorta development, epithelial cell proliferation involved in salivary gland morphogenesis, heart development, male gonad development, metanephros development, mitotic cell cycle arrest, multicellular organismal development, negative regulation of cell proliferation, negative regulation of epithelial cell proliferation, negative regulation of epithelial cell proliferation involved in prostate gland development, negative regulation of estrogen receptor binding, negative regulation of insulin-like growth factor receptor signaling pathway, negative regulation of mitotic cell cycle, negative regulation of transcription, DNA-dependent, pharyngeal system development, positive regulation of androgen secretion, positive regulation of apoptotic signaling pathway, positive regulation of cell death, positive regulation of cell division, positive regulation of intrinsic apoptotic signaling pathway, positive regulation of mitotic cell cycle, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of protein kinase activity, positive regulation of response to DNA damage stimulus, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein kinase B signaling cascade, regulation of transcription, DNA-dependent, response to testosterone stimulus, salivary gland development, somitogenesis intracellular, nucleus MADS box domain binding, RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity, androgen receptor activity, cysteine-type endopeptidase activator activity involved in apoptotic process, estrogen receptor activity, estrogen receptor binding, histone deacetylase binding, protein binding, protein self-association, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding, transcription regulatory region sequence-specific DNA binding Human NKX3-2 PINC UniProtKB {GO:0060576=GO_REF:0000019, GO:0007368=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0006366=PMID:9344671, GO:0048706=GO_REF:0000019, GO:0048705=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0048536=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0048645=GO_REF:0000019, GO:0001501=PMID:9344671, GO:0031016=GO_REF:0000019, GO:0042474=GO_REF:0000019, GO:0032331=GO_REF:0000024} P78367 Homeobox protein Nkx-3.2 protein 20030904 {GO:0060576=IEA, GO:0007368=IEA, GO:0043066=IEA, GO:0003700=IEA, GO:0006366=TAS, GO:0048706=IEA, GO:0048705=IEA, GO:0005634=IEA, GO:0048536=IEA, GO:0043565=IEA, GO:0048645=IEA, GO:0001501=TAS, GO:0031016=IEA, GO:0042474=IEA, GO:0032331=ISS} determination of left/right symmetry, embryonic skeletal system development, intestinal epithelial cell development, middle ear morphogenesis, negative regulation of apoptotic process, negative regulation of chondrocyte differentiation, organ formation, pancreas development, skeletal system development, skeletal system morphogenesis, spleen development, transcription from RNA polymerase II promoter nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human NLE1 HPA UniProtKB {GO:0007219=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0001826=GO_REF:0000019, GO:0005634=GO_REF:0000052} Q9NVX2 Notchless protein homolog 1 protein 20081203 {GO:0007219=IEA, GO:0005730=IDA, GO:0001826=IEA, GO:0005634=IDA} Notch signaling pathway, inner cell mass cell differentiation nucleolus, nucleus Human NLGN1 BHF-UCL UniProtKB {GO:0004091=GO_REF:0000033, GO:0030054=GO_REF:0000037, GO:0017146=GO_REF:0000019, GO:2000311=GO_REF:0000024, GO:0045202=GO_REF:0000024, GO:2000310=GO_REF:0000024, GO:0051491=GO_REF:0000024, GO:0006605=GO_REF:0000024, GO:0016339=GO_REF:0000024, GO:1900029=GO_REF:0000024, GO:0045211=GO_REF:0000037, GO:0046983=GO_REF:0000024, GO:0051260=GO_REF:0000024, GO:0060999=GO_REF:0000024, GO:0050839=GO_REF:0000024, GO:0097091=GO_REF:0000024, GO:0048789=GO_REF:0000024, GO:0051965=GO_REF:0000024, GO:0010740=GO_REF:0000024, GO:0009986=GO_REF:0000024, GO:2000463=GO_REF:0000024, GO:0051968=GO_REF:0000024, GO:0014069=PMID:15797875, GO:0007416=GO_REF:0000024, GO:0032230=GO_REF:0000024, GO:0005887=GO_REF:0000024, GO:0023041=PMID:15797875, GO:0016080=GO_REF:0000024, GO:0097120=GO_REF:0000024, GO:0051290=GO_REF:0000019, GO:1900244=GO_REF:0000024, GO:0032433=GO_REF:0000019, GO:0030425=GO_REF:0000024, GO:0045184=GO_REF:0000024, GO:0002087=GO_REF:0000019, GO:0097115=GO_REF:0000024, GO:0097114=GO_REF:0000019, GO:0097113=GO_REF:0000024, GO:0004872=GO_REF:0000024, GO:0097119=GO_REF:0000024, GO:0007157=GO_REF:0000024, GO:0007158=GO_REF:0000024, GO:2000302=GO_REF:0000024, GO:0072553=GO_REF:0000024, GO:0042043=GO_REF:0000024, GO:0007399=GO_REF:0000024, GO:0097104=GO_REF:0000024, GO:0097105=GO_REF:0000024, GO:0045664=GO_REF:0000024} Q8N2Q7 Neuroligin-1 protein 20120314 {GO:0004091=IKR, GO:0030054=IEA, GO:0017146=IEA, GO:2000311=ISS, GO:0045202=ISS, GO:2000310=ISS, GO:0051491=ISS, GO:0006605=ISS, GO:0016339=ISS, GO:1900029=ISS, GO:0045211=IEA, GO:0046983=ISS, GO:0051260=ISS, GO:0060999=ISS, GO:0050839=ISS, GO:0097091=ISS, GO:0048789=ISS, GO:0051965=ISS, GO:0010740=ISS, GO:0009986=ISS, GO:2000463=ISS, GO:0051968=ISS, GO:0014069=TAS, GO:0007416=ISS, GO:0032230=ISS, GO:0005887=ISS, GO:0023041=TAS, GO:0016080=ISS, GO:0097120=ISS, GO:0051290=IEA, GO:1900244=ISS, GO:0032433=IEA, GO:0030425=ISS, GO:0045184=ISS, GO:0002087=IEA, GO:0097115=ISS, GO:0097114=IEA, GO:0097113=ISS, GO:0004872=ISS, GO:0097119=ISS, GO:0007157=ISS, GO:0007158=ISS, GO:2000302=ISS, GO:0072553=ISS, GO:0042043=ISS, GO:0007399=ISS, GO:0097104=ISS, GO:0097105=ISS, GO:0045664=ISS} N-methyl-D-aspartate receptor clustering, alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering, calcium-dependent cell-cell adhesion, cytoskeletal matrix organization at active zone, establishment of protein localization, heterophilic cell-cell adhesion, nervous system development, neurexin clustering, neuron cell-cell adhesion, neuronal signal transduction, positive regulation of dendritic spine development, positive regulation of excitatory postsynaptic membrane potential, positive regulation of filopodium assembly, positive regulation of intracellular protein kinase cascade, positive regulation of ruffle assembly, positive regulation of synapse assembly, positive regulation of synaptic transmission, GABAergic, positive regulation of synaptic transmission, glutamatergic, positive regulation of synaptic vesicle endocytosis, positive regulation of synaptic vesicle exocytosis, postsynaptic density protein 95 clustering, postsynaptic membrane assembly, presynaptic membrane assembly, protein heterotetramerization, protein homooligomerization, protein targeting, receptor localization to synapse, regulation of N-methyl-D-aspartate selective glutamate receptor activity, regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity, regulation of neuron differentiation, regulation of respiratory gaseous exchange by neurological system process, synapse assembly, synaptic vesicle clustering, synaptic vesicle targeting, terminal button organization N-methyl-D-aspartate selective glutamate receptor complex, cell junction, cell surface, dendrite, filopodium tip, integral to plasma membrane, postsynaptic density, postsynaptic membrane, synapse carboxylesterase activity, cell adhesion molecule binding, neurexin family protein binding, protein dimerization activity, receptor activity Human UniProtKB:Q62765 NLGN2 BHF-UCL UniProtKB {GO:0004091=GO_REF:0000033, GO:0030054=GO_REF:0000037, GO:2000311=GO_REF:0000024, GO:0045202=GO_REF:0000033, GO:0035418=GO_REF:0000024, GO:0097116=GO_REF:0000024, GO:0002087=GO_REF:0000019, GO:0016337=PMID:10892652, GO:0045211=PMID:10892652, GO:0050885=GO_REF:0000019, GO:0004872=GO_REF:0000033, GO:0050839=GO_REF:0000024, GO:0097119=GO_REF:0000024, GO:0007158=GO_REF:0000024, GO:0035641=GO_REF:0000019, GO:0051965=GO_REF:0000024, GO:0097151=GO_REF:0000024, GO:2000463=GO_REF:0000024, GO:0009986=GO_REF:0000024, GO:0051968=GO_REF:0000024, GO:0060077=GO_REF:0000024, GO:0072553=GO_REF:0000024, GO:0042043=GO_REF:0000024, GO:0007416=GO_REF:0000024, GO:0019233=GO_REF:0000019, GO:0032230=GO_REF:0000024, GO:0045217=PMID:10892652, GO:0097104=GO_REF:0000024, GO:0042734=GO_REF:0000039, GO:0097105=GO_REF:0000024, GO:0016020=PMID:10892652, GO:0005887=GO_REF:0000024} Q8NFZ4 Neuroligin-2 protein 20110818 {GO:0004091=IKR, GO:0030054=IEA, GO:2000311=ISS, GO:0045202=IBA, GO:0035418=ISS, GO:0097116=ISS, GO:0002087=IEA, GO:0016337=NAS, GO:0045211=NAS, GO:0050885=IEA, GO:0004872=IBA, GO:0050839=ISS, GO:0097119=ISS, GO:0007158=ISS, GO:0035641=IEA, GO:0051965=ISS, GO:0097151=ISS, GO:2000463=ISS, GO:0009986=ISS, GO:0051968=ISS, GO:0060077=ISS, GO:0072553=ISS, GO:0042043=ISS, GO:0007416=ISS, GO:0019233=IEA, GO:0032230=ISS, GO:0045217=NAS, GO:0097104=ISS, GO:0042734=IEA, GO:0097105=ISS, GO:0016020=NAS, GO:0005887=ISS} cell-cell adhesion, cell-cell junction maintenance, gephyrin clustering, locomotory exploration behavior, neuromuscular process controlling balance, neuron cell-cell adhesion, positive regulation of excitatory postsynaptic membrane potential, positive regulation of inhibitory postsynaptic membrane potential, positive regulation of synapse assembly, positive regulation of synaptic transmission, GABAergic, positive regulation of synaptic transmission, glutamatergic, postsynaptic density protein 95 clustering, postsynaptic membrane assembly, presynaptic membrane assembly, protein localization to synapse, regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity, regulation of respiratory gaseous exchange by neurological system process, sensory perception of pain, synapse assembly, terminal button organization cell junction, cell surface, inhibitory synapse, integral to plasma membrane, membrane, postsynaptic membrane, presynaptic membrane, synapse carboxylesterase activity, cell adhesion molecule binding, neurexin family protein binding, receptor activity Human UniProtKB:Q62888 NLGN3 HPA UniProtKB {GO:0004091=GO_REF:0000033, GO:0005515=PMID:17292328, GO:0030054=GO_REF:0000037, GO:2000310=GO_REF:0000019, GO:0045202=GO_REF:0000024, GO:0048675=GO_REF:0000024, GO:0030139=GO_REF:0000024, GO:2000331=GO_REF:0000019, GO:0002087=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0004872=GO_REF:0000024, GO:0060024=GO_REF:0000024, GO:0061001=GO_REF:0000019, GO:0007155=GO_REF:0000002, GO:0050839=PMID:15152050, GO:2000969=GO_REF:0000024, GO:0007158=GO_REF:0000024, GO:0051965=GO_REF:0000024, GO:2000463=GO_REF:0000024, GO:0009986=PMID:15150161, GO:0051968=GO_REF:0000024, GO:1900271=GO_REF:0000019, GO:0060076=PMID:15620359, GO:0007416=GO_REF:0000024, GO:0042043=PMID:15152050, GO:0006898=GO_REF:0000024, GO:0097104=GO_REF:0000024, GO:0097105=GO_REF:0000024, GO:0060080=GO_REF:0000024, GO:0016020=GO_REF:0000002, GO:0050808=PMID:15150161, GO:0005887=GO_REF:0000024, GO:0008542=GO_REF:0000019, GO:0035176=PMID:12669065} Q9NZ94 Neuroligin-3 protein 20080205 {GO:0004091=IKR, GO:0005515=IPI, GO:0030054=IEA, GO:2000310=IEA, GO:0045202=ISS, GO:0048675=ISS, GO:0030139=ISS, GO:2000331=IEA, GO:0002087=IEA, GO:0005737=IDA, GO:0004872=ISS, GO:0060024=ISS, GO:0061001=IEA, GO:0007155=IEA, GO:0050839=ISS, GO:2000969=ISS, GO:0007158=ISS, GO:0051965=ISS, GO:2000463=ISS, GO:0009986=IDA, GO:0051968=ISS, GO:1900271=IEA, GO:0060076=IDA, GO:0007416=ISS, GO:0042043=ISS, GO:0006898=ISS, GO:0097104=ISS, GO:0097105=ISS, GO:0060080=ISS, GO:0016020=IEA, GO:0050808=IMP, GO:0005887=ISS, GO:0008542=IEA, GO:0035176=IMP} axon extension, cell adhesion, neuron cell-cell adhesion, positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity, positive regulation of excitatory postsynaptic membrane potential, positive regulation of synapse assembly, positive regulation of synaptic transmission, glutamatergic, postsynaptic membrane assembly, presynaptic membrane assembly, receptor-mediated endocytosis, regulation of N-methyl-D-aspartate selective glutamate receptor activity, regulation of dendritic spine morphogenesis, regulation of inhibitory postsynaptic membrane potential, regulation of long-term synaptic potentiation, regulation of respiratory gaseous exchange by neurological system process, regulation of terminal button organization, rhythmic synaptic transmission, social behavior, synapse assembly, synapse organization, visual learning cell junction, cell surface, cytoplasm, endocytic vesicle, excitatory synapse, integral to plasma membrane, membrane, synapse carboxylesterase activity, cell adhesion molecule binding, neurexin family protein binding, protein binding, receptor activity Human NLGN4X BHF-UCL UniProtKB {GO:0005515=PMID:11368788, GO:0004091=GO_REF:0000033, GO:0031404=PMID:18093521, GO:0030054=GO_REF:0000037, GO:0005886=PMID:19726642, GO:0045202=PMID:18227507, GO:0030425=PMID:19726642, GO:0042803=PMID:18093521, GO:0045211=GO_REF:0000037, GO:0004872=GO_REF:0000033, GO:0007155=GO_REF:0000037, GO:0046622=PMID:18227507, GO:0009986=PMID:19726642, GO:0003360=PMID:18227507, GO:0014069=GO_REF:0000039, GO:0021549=PMID:18227507, GO:0042043=PMID:19726642, GO:0071625=PMID:18227507, GO:0060076=PMID:15620359, GO:0045216=PMID:11368788, GO:0090394=PMID:19726642, GO:0097105=PMID:19726642, GO:0050808=PMID:11368788, GO:0005887=PMID:11368788, GO:0035176=PMID:19726642, GO:0016021=PMID:16377159} Q8N0W4 Neuroligin-4, X-linked protein 20110309 {GO:0005515=IPI, GO:0004091=IKR, GO:0031404=IDA, GO:0030054=IEA, GO:0005886=IDA, GO:0045202=ISS, GO:0030425=IDA, GO:0042803=IDA, GO:0045211=IEA, GO:0004872=IBA, GO:0007155=IEA, GO:0046622=ISS, GO:0009986=IDA, GO:0003360=ISS, GO:0014069=IEA, GO:0021549=ISS, GO:0042043=IDA, GO:0071625=ISS, GO:0060076=IDA, GO:0045216=NAS, GO:0090394=IDA, GO:0097105=IDA, GO:0050808=NAS, GO:0005887=IDA, GO:0035176=IMP, GO:0016021=NAS} brainstem development, cell adhesion, cell-cell junction organization, cerebellum development, negative regulation of excitatory postsynaptic membrane potential, positive regulation of organ growth, presynaptic membrane assembly, social behavior, synapse organization, vocalization behavior cell junction, cell surface, dendrite, excitatory synapse, integral to membrane, integral to plasma membrane, plasma membrane, postsynaptic density, postsynaptic membrane, synapse carboxylesterase activity, chloride ion binding, neurexin family protein binding, protein binding, protein homodimerization activity, receptor activity Human UniProtKB:B0F2B4 NLK IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0006355=GO_REF:0000024, GO:0000287=GO_REF:0000024, GO:0030178=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0005524=GO_REF:0000024, GO:0007243=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0042802=PMID:19345186, GO:0005737=GO_REF:0000039, GO:0004672=PMID:10863097, GO:0046777=GO_REF:0000019, GO:0033136=GO_REF:0000024, GO:0018107=GO_REF:0000024, GO:0007179=PMID:15004007, GO:0006468=GO_REF:0000024, GO:0016055=GO_REF:0000037, GO:0042169=GO_REF:0000024, GO:0031625=PMID:16714285, GO:0008134=PMID:16714285, GO:0004707=GO_REF:0000024} Q9UBE8 Serine/threonine-protein kinase NLK protein 20130415 {GO:0005515=IPI, GO:0006355=ISS, GO:0000287=ISS, GO:0030178=ISS, GO:0005634=ISS, GO:0005524=ISS, GO:0007243=ISS, GO:0006351=IEA, GO:0042802=IPI, GO:0005737=IEA, GO:0004672=TAS, GO:0046777=IEA, GO:0033136=ISS, GO:0018107=ISS, GO:0007179=IMP, GO:0006468=ISS, GO:0016055=IEA, GO:0042169=ISS, GO:0031625=IPI, GO:0008134=IPI, GO:0004707=ISS} Wnt receptor signaling pathway, intracellular protein kinase cascade, negative regulation of Wnt receptor signaling pathway, peptidyl-threonine phosphorylation, protein autophosphorylation, protein phosphorylation, regulation of transcription, DNA-dependent, serine phosphorylation of STAT3 protein, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway cytoplasm, nucleus ATP binding, MAP kinase activity, SH2 domain binding, identical protein binding, magnesium ion binding, protein binding, protein kinase activity, transcription factor binding, ubiquitin protein ligase binding Human UniProtKB:Q9UBE8 NLN UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0005758=GO_REF:0000039, GO:0006508=GO_REF:0000037, GO:0004222=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q9BYT8 Neurolysin, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0005758=IEA, GO:0006508=IEA, GO:0004222=IEA, GO:0046872=IEA} proteolysis mitochondrial intermembrane space, mitochondrion metal ion binding, metalloendopeptidase activity Human UniProtKB-SubCell:SL-0169 NLRC3 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0042110=PMID:15705585, GO:0005737=PMID:15705585, GO:0007249=PMID:15705585, GO:0032088=PMID:15705585, GO:0005524=GO_REF:0000037} Q7RTR2 Protein NLRC3 protein 20110126 {GO:0003674=ND, GO:0042110=IEP, GO:0005737=IDA, GO:0007249=IDA, GO:0032088=IDA, GO:0005524=IEA} I-kappaB kinase/NF-kappaB cascade, T cell activation, negative regulation of NF-kappaB transcription factor activity cytoplasm ATP binding, molecular_function Human NLRC4 IntAct UniProtKB {GO:0005515=PMID:17418785, GO:0000287=PMID:15882992, GO:0043065=PMID:11374873, GO:0006919=PMID:15030775, GO:0072557=GO_REF:0000024, GO:0050702=PMID:15882992, GO:0002218=GO_REF:0000024, GO:0005524=PMID:15882992, GO:0035872=Reactome:REACT_75913, GO:0070269=GO_REF:0000024, GO:0042803=PMID:15107016, GO:0042802=PMID:11390368, GO:0005829=Reactome:REACT_75785, GO:0005622=PMID:15107016, GO:0051092=PMID:12646168, GO:0006954=GO_REF:0000024, GO:0045087=Reactome:REACT_6802, GO:0051260=GO_REF:0000024, GO:0016045=PMID:15107016, GO:0042742=PMID:15107016} Q9NPP4 NLR family CARD domain-containing protein 4 protein 20130415 {GO:0005515=IPI, GO:0000287=TAS, GO:0043065=IMP, GO:0006919=IDA, GO:0072557=ISS, GO:0050702=IDA, GO:0002218=ISS, GO:0005524=IDA, GO:0035872=TAS, GO:0070269=ISS, GO:0042803=IDA, GO:0042802=IPI, GO:0005829=TAS, GO:0005622=NAS, GO:0051092=IDA, GO:0006954=ISS, GO:0045087=TAS, GO:0051260=ISS, GO:0016045=IDA, GO:0042742=IDA} activation of cysteine-type endopeptidase activity involved in apoptotic process, activation of innate immune response, defense response to bacterium, detection of bacterium, inflammatory response, innate immune response, interleukin-1 beta secretion, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, positive regulation of NF-kappaB transcription factor activity, positive regulation of apoptotic process, protein homooligomerization, pyroptosis IPAF inflammasome complex, cytosol, intracellular ATP binding, identical protein binding, magnesium ion binding, protein binding, protein homodimerization activity Human UniProtKB:Q9NPP4 NLRC5 BHF-UCL UniProtKB {GO:0005515=PMID:20434986, GO:0032088=PMID:20434986, GO:0005634=PMID:20639463, GO:0000979=PMID:20639463, GO:0005524=GO_REF:0000037, GO:0005829=PMID:20639463, GO:0060335=PMID:20639463, GO:0005737=PMID:20434986, GO:0051607=PMID:20061403, GO:0045345=PMID:20639463, GO:0060339=PMID:20434986, GO:0045944=PMID:20639463, GO:0045087=Reactome:REACT_6802, GO:0060340=PMID:20061403, GO:0032480=Reactome:REACT_25271, GO:0043549=PMID:20434986} Q86WI3 Protein NLRC5 protein 20110309 {GO:0005515=IPI, GO:0032088=IDA, GO:0005634=IDA, GO:0000979=IDA, GO:0005524=IEA, GO:0005829=IDA, GO:0060335=IMP, GO:0005737=IDA, GO:0051607=IEP, GO:0045345=IDA, GO:0060339=IDA, GO:0045944=IDA, GO:0045087=TAS, GO:0060340=IDA, GO:0032480=TAS, GO:0043549=IDA} defense response to virus, innate immune response, negative regulation of NF-kappaB transcription factor activity, negative regulation of type I interferon production, negative regulation of type I interferon-mediated signaling pathway, positive regulation of MHC class I biosynthetic process, positive regulation of interferon-gamma-mediated signaling pathway, positive regulation of transcription from RNA polymerase II promoter, positive regulation of type I interferon-mediated signaling pathway, regulation of kinase activity cytoplasm, cytosol, nucleus ATP binding, RNA polymerase II core promoter sequence-specific DNA binding, protein binding Human NLRP1 BHF-UCL UniProtKB {GO:0005515=PMID:19337385, GO:0006919=PMID:15212762, GO:0019904=PMID:16575408, GO:0072558=PMID:20303873, GO:0050727=PMID:15212762, GO:0005634=PMID:17164409, GO:0006952=GO_REF:0000002, GO:0006917=PMID:15212762, GO:0051402=PMID:15212762, GO:0005524=PMID:15212762, GO:0008656=PMID:11076957, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_75872, GO:0005622=PMID:11076957, GO:0050718=GO_REF:0000024, GO:0045087=Reactome:REACT_6802, GO:0032495=GO_REF:0000024, GO:0019899=PMID:11076957, GO:0042742=GO_REF:0000024} Q9C000 NACHT, LRR and PYD domains-containing protein 1 protein 20110124 {GO:0005515=IPI, GO:0006919=IDA, GO:0019904=IPI, GO:0072558=TAS, GO:0050727=IC, GO:0005634=IDA, GO:0006952=IEA, GO:0006917=IDA, GO:0051402=IDA, GO:0005524=IDA, GO:0008656=NAS, GO:0035872=TAS, GO:0005829=TAS, GO:0005622=IC, GO:0050718=ISS, GO:0045087=TAS, GO:0032495=ISS, GO:0019899=IPI, GO:0042742=ISS} activation of cysteine-type endopeptidase activity involved in apoptotic process, defense response, defense response to bacterium, induction of apoptosis, innate immune response, neuron apoptotic process, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, positive regulation of interleukin-1 beta secretion, regulation of inflammatory response, response to muramyl dipeptide NLRP1 inflammasome complex, cytosol, intracellular, nucleus ATP binding, cysteine-type endopeptidase activator activity involved in apoptotic process, enzyme binding, protein binding, protein domain specific binding Human UniProtKB:Q67EY4 NLRP10 UniProtKB UniProtKB {GO:0050829=PMID:22672233, GO:2000318=GO_REF:0000024, GO:0005737=PMID:22672233, GO:0036336=GO_REF:0000024, GO:2000778=PMID:22672233, GO:0002827=GO_REF:0000024, GO:0045087=GO_REF:0000037, GO:0050832=GO_REF:0000024, GO:0035397=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:2000484=PMID:22672233, GO:0019897=PMID:22672233} Q86W26 NACHT, LRR and PYD domains-containing protein 10 protein 20121107 {GO:0050829=IMP, GO:2000318=ISS, GO:0005737=IDA, GO:0036336=ISS, GO:2000778=IMP, GO:0002827=ISS, GO:0045087=IEA, GO:0050832=ISS, GO:0035397=ISS, GO:0005524=IEA, GO:2000484=IMP, GO:0019897=IDA} defense response to Gram-negative bacterium, defense response to fungus, dendritic cell migration, helper T cell enhancement of adaptive immune response, innate immune response, positive regulation of T-helper 1 type immune response, positive regulation of T-helper 17 type immune response, positive regulation of interleukin-6 secretion, positive regulation of interleukin-8 secretion cytoplasm, extrinsic to plasma membrane ATP binding Human NLRP11 UniProtKB UniProtKB {GO:0016715=GO_REF:0000002, GO:0005524=GO_REF:0000037} P59045 NACHT, LRR and PYD domains-containing protein 11 protein 20130413 {GO:0016715=IEA, GO:0005524=IEA} ATP binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen Human UniProtKB-KW:KW-0067 NLRP12 BHF-UCL UniProtKB {GO:0005515=PMID:19337385, GO:0045381=PMID:12019269, GO:0006919=PMID:12019269, GO:0045751=PMID:16203735, GO:0045409=PMID:16203735, GO:0032088=PMID:18230725, GO:0050710=PMID:16203735, GO:0005524=GO_REF:0000037, GO:0008656=PMID:12019269, GO:0050711=PMID:16203735, GO:0031953=PMID:16203735, GO:0007165=PMID:12019269, GO:0008588=PMID:12019269, GO:0005737=PMID:12019269, GO:0050718=PMID:12019269, GO:0050728=PMID:18230725, GO:0050729=PMID:12019269, GO:0009968=PMID:16203735, GO:0043124=PMID:16203735} P59046 NACHT, LRR and PYD domains-containing protein 12 protein 20110124 {GO:0005515=IPI, GO:0045381=NAS, GO:0006919=NAS, GO:0045751=IDA, GO:0045409=IDA, GO:0032088=IDA, GO:0050710=IDA, GO:0005524=IEA, GO:0008656=NAS, GO:0050711=IDA, GO:0031953=IDA, GO:0007165=NAS, GO:0008588=IDA, GO:0005737=IDA, GO:0050718=NAS, GO:0050728=IMP, GO:0050729=NAS, GO:0009968=IDA, GO:0043124=IDA} activation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of I-kappaB kinase/NF-kappaB cascade, negative regulation of NF-kappaB transcription factor activity, negative regulation of Toll signaling pathway, negative regulation of cytokine secretion, negative regulation of inflammatory response, negative regulation of interleukin-1 secretion, negative regulation of interleukin-6 biosynthetic process, negative regulation of protein autophosphorylation, negative regulation of signal transduction, positive regulation of inflammatory response, positive regulation of interleukin-1 beta secretion, regulation of interleukin-18 biosynthetic process, release of cytoplasmic sequestered NF-kappaB, signal transduction cytoplasm ATP binding, cysteine-type endopeptidase activator activity involved in apoptotic process, protein binding Human UniProtKB:Q9HC29 NLRP2 IntAct UniProtKB {GO:0005515=PMID:17178784, GO:0043280=PMID:15030775, GO:0032090=PMID:15030775, GO:0005737=PMID:15030775, GO:0050718=PMID:15030775, GO:0005524=GO_REF:0000037} Q9NX02 NACHT, LRR and PYD domains-containing protein 2 protein 20130415 {GO:0005515=IPI, GO:0043280=IDA, GO:0032090=IPI, GO:0005737=IDA, GO:0050718=IDA, GO:0005524=IEA} positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of interleukin-1 beta secretion cytoplasm ATP binding, Pyrin domain binding, protein binding Human UniProtKB:Q56P42 NLRP3 BHF-UCL UniProtKB {GO:0005515=PMID:19337385, GO:0042347=PMID:14662828, GO:0051259=PMID:15967716, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_75877, GO:0051607=GO_REF:0000019, GO:0005737=PMID:17164409, GO:0051092=PMID:19158675, GO:0006954=PMID:12093792, GO:0050718=PMID:15030775, GO:0009595=PMID:15967716, GO:0032621=GO_REF:0000019, GO:0072559=PMID:15030775, GO:0050701=GO_REF:0000019, GO:0006919=GO_REF:0000019, GO:0042834=PMID:15967716, GO:0006952=PMID:15967716, GO:0032088=PMID:14662828, GO:0006917=PMID:12032915, GO:0002674=PMID:11687797, GO:0005524=GO_REF:0000037, GO:0043280=PMID:15030775, GO:0007165=PMID:11786556, GO:0045087=Reactome:REACT_6802, GO:0050728=PMID:17178985} Q96P20 NACHT, LRR and PYD domains-containing protein 3 protein 20110124 {GO:0005515=IPI, GO:0042347=IDA, GO:0051259=TAS, GO:0035872=TAS, GO:0005829=TAS, GO:0051607=IEA, GO:0005737=IDA, GO:0051092=IDA, GO:0006954=IMP, GO:0050718=IDA, GO:0009595=TAS, GO:0032621=IEA, GO:0072559=IDA, GO:0050701=IEA, GO:0006919=IEA, GO:0042834=TAS, GO:0006952=TAS, GO:0032088=IDA, GO:0006917=NAS, GO:0002674=IMP, GO:0005524=IEA, GO:0043280=IDA, GO:0007165=NAS, GO:0045087=TAS, GO:0050728=IMP} activation of cysteine-type endopeptidase activity involved in apoptotic process, defense response, defense response to virus, detection of biotic stimulus, induction of apoptosis, inflammatory response, innate immune response, interleukin-1 secretion, interleukin-18 production, negative regulation of NF-kappaB import into nucleus, negative regulation of NF-kappaB transcription factor activity, negative regulation of acute inflammatory response, negative regulation of inflammatory response, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, positive regulation of NF-kappaB transcription factor activity, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of interleukin-1 beta secretion, protein oligomerization, signal transduction NLRP3 inflammasome complex, cytoplasm, cytosol ATP binding, peptidoglycan binding, protein binding Human UniProtKB:Q9HC29 NLRP4 UniProtKB UniProtKB {GO:0005524=GO_REF:0000037} Q96MN2 NACHT, LRR and PYD domains-containing protein 4 protein 20130413 {GO:0005524=IEA} ATP binding Human UniProtKB-KW:KW-0067 NLRP5 UniProtKB UniProtKB {GO:0043487=GO_REF:0000019, GO:0007566=GO_REF:0000019, GO:0005730=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0001701=GO_REF:0000019, GO:0043623=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0009566=GO_REF:0000019, GO:0005739=GO_REF:0000024, GO:0043234=GO_REF:0000019, GO:0031647=GO_REF:0000019, GO:0045179=GO_REF:0000019, GO:0009887=GO_REF:0000019} P59047 NACHT, LRR and PYD domains-containing protein 5 protein 20070411 {GO:0043487=IEA, GO:0007566=IEA, GO:0005730=ISS, GO:0005524=IEA, GO:0001701=IEA, GO:0043623=IEA, GO:0005829=IEA, GO:0009566=IEA, GO:0005739=ISS, GO:0043234=IEA, GO:0031647=IEA, GO:0045179=IEA, GO:0009887=IEA} cellular protein complex assembly, embryo implantation, fertilization, in utero embryonic development, organ morphogenesis, regulation of RNA stability, regulation of protein stability apical cortex, cytosol, mitochondrion, nucleolus, protein complex ATP binding Human UniProtKB:Q9R1M5 NLRP7 UniProtKB UniProtKB {GO:0006952=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q8WX94 NACHT, LRR and PYD domains-containing protein 7 protein 20130413 {GO:0006952=IEA, GO:0005524=IEA} defense response ATP binding Human UniProtKB-KW:KW-0067 NLRX1 IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0005739=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0019048=GO_REF:0000037, GO:0005741=Reactome:REACT_25223, GO:0032480=Reactome:REACT_25271, GO:0005524=GO_REF:0000037} Q86UT6 NLR family member X1 protein 20130415 {GO:0005515=IPI, GO:0005739=IEA, GO:0045087=TAS, GO:0019048=IEA, GO:0005741=TAS, GO:0032480=TAS, GO:0005524=IEA} innate immune response, negative regulation of type I interferon production, virus-host interaction mitochondrial outer membrane, mitochondrion ATP binding, protein binding Human UniProtKB:Q6PDS3 NMB Reactome UniProtKB {GO:0008343=GO_REF:0000019, GO:0031710=GO_REF:0000019, GO:0043005=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0007267=PMID:2458345, GO:0005576=Reactome:REACT_22436, GO:0042593=GO_REF:0000019, GO:0007204=GO_REF:0000019, GO:0046888=GO_REF:0000019, GO:0007165=PMID:2458345, GO:0005179=PMID:2458345, GO:0007218=GO_REF:0000002, GO:0046887=GO_REF:0000019, GO:0050482=GO_REF:0000019} P08949 Neuromedin-B protein 20080826 {GO:0008343=IEA, GO:0031710=IEA, GO:0043005=IEA, GO:0008284=IEA, GO:0007267=TAS, GO:0005576=TAS, GO:0042593=IEA, GO:0007204=IEA, GO:0046888=IEA, GO:0007165=TAS, GO:0005179=TAS, GO:0007218=IEA, GO:0046887=IEA, GO:0050482=IEA} adult feeding behavior, arachidonic acid secretion, cell-cell signaling, elevation of cytosolic calcium ion concentration, glucose homeostasis, negative regulation of hormone secretion, neuropeptide signaling pathway, positive regulation of cell proliferation, positive regulation of hormone secretion, signal transduction extracellular region, neuron projection hormone activity, neuromedin B receptor binding Human NMBR HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0004946=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0007186=PMID:1655761, GO:0005887=PMID:8391296, GO:0007200=PMID:7838118} P28336 Neuromedin-B receptor protein 20101115 {GO:0005737=IDA, GO:0004946=IEA, GO:0005886=IDA, GO:0007186=TAS, GO:0005887=TAS, GO:0007200=TAS} G-protein coupled receptor signaling pathway, phospholipase C-activating G-protein coupled receptor signaling pathway cytoplasm, integral to plasma membrane, plasma membrane bombesin receptor activity Human NMD3 HPA UniProtKB {GO:0005737=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005654=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0015031=GO_REF:0000037} Q96D46 60S ribosomal export protein NMD3 protein 20101115 {GO:0005737=IEA, GO:0005730=IDA, GO:0005654=IEA, GO:0005634=IDA, GO:0015031=IEA} protein transport cytoplasm, nucleolus, nucleoplasm, nucleus Human NME1 HPA UniProtKB {GO:0005515=PMID:21988832, GO:0006241=GO_REF:0000002, GO:0048471=GO_REF:0000019, GO:0008285=PMID:1851158, GO:0004550=PMID:12972261, GO:0005634=PMID:16130169, GO:0044281=Reactome:REACT_111217, GO:0002762=GO_REF:0000019, GO:0014075=GO_REF:0000019, GO:0051591=GO_REF:0000019, GO:0042802=PMID:17314099, GO:0005829=Reactome:REACT_21416, GO:0071398=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0003697=GO_REF:0000019, GO:0043024=PMID:16814409, GO:0071333=GO_REF:0000019, GO:0050679=PMID:16862176, GO:0005813=GO_REF:0000019, GO:0015949=Reactome:REACT_21330, GO:0000287=PMID:11555662, GO:0000977=GO_REF:0000019, GO:0019901=GO_REF:0000019, GO:0043015=GO_REF:0000019, GO:0055086=Reactome:REACT_1698, GO:0042981=PMID:16130169, GO:0005525=PMID:12972261, GO:0033574=GO_REF:0000019, GO:0005524=PMID:12972261, GO:0035690=GO_REF:0000019, GO:0019215=GO_REF:0000019, GO:0006897=GO_REF:0000037, GO:0006228=GO_REF:0000002, GO:0006183=GO_REF:0000002, GO:0021766=GO_REF:0000019, GO:0004536=PMID:11555662, GO:0016020=GO_REF:0000019, GO:0043388=PMID:17975005, GO:0010976=GO_REF:0000019, GO:0010629=GO_REF:0000019} P15531 Nucleoside diphosphate kinase A protein 20080205 {GO:0005515=IPI, GO:0006241=IEA, GO:0048471=IEA, GO:0008285=TAS, GO:0004550=IDA, GO:0005634=TAS, GO:0044281=TAS, GO:0002762=IEA, GO:0014075=IEA, GO:0051591=IEA, GO:0042802=IPI, GO:0005829=TAS, GO:0071398=IEA, GO:0005737=IDA, GO:0003697=IEA, GO:0043024=IPI, GO:0071333=IEA, GO:0050679=IMP, GO:0005813=IEA, GO:0015949=TAS, GO:0000287=IDA, GO:0000977=IEA, GO:0019901=IEA, GO:0043015=IEA, GO:0055086=TAS, GO:0042981=TAS, GO:0005525=IDA, GO:0033574=IEA, GO:0005524=IDA, GO:0035690=IEA, GO:0019215=IEA, GO:0006897=IEA, GO:0006228=IEA, GO:0006183=IEA, GO:0021766=IEA, GO:0004536=IDA, GO:0016020=IEA, GO:0043388=IDA, GO:0010976=IEA, GO:0010629=IEA} CTP biosynthetic process, GTP biosynthetic process, UTP biosynthetic process, cellular response to drug, cellular response to fatty acid, cellular response to glucose stimulus, endocytosis, hippocampus development, negative regulation of cell proliferation, negative regulation of gene expression, negative regulation of myeloid leukocyte differentiation, nucleobase-containing small molecule interconversion, nucleobase-containing small molecule metabolic process, positive regulation of DNA binding, positive regulation of epithelial cell proliferation, positive regulation of neuron projection development, regulation of apoptotic process, response to amine stimulus, response to cAMP, response to testosterone stimulus, small molecule metabolic process centrosome, cytoplasm, cytosol, membrane, nucleus, perinuclear region of cytoplasm ATP binding, GTP binding, RNA polymerase II regulatory region sequence-specific DNA binding, deoxyribonuclease activity, gamma-tubulin binding, identical protein binding, intermediate filament binding, magnesium ion binding, nucleoside diphosphate kinase activity, protein binding, protein kinase binding, ribosomal small subunit binding, single-stranded DNA binding Human NME2 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0006241=GO_REF:0000002, GO:0003700=PMID:8392752, GO:0045682=PMID:16862176, GO:0004550=PMID:1851158, GO:0005634=GO_REF:0000029, GO:0009142=PMID:1851158, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_21416, GO:0045618=PMID:16862176, GO:0007155=PMID:11919189, GO:0050679=PMID:16862176, GO:0006355=PMID:8392752, GO:0043066=PMID:16862176, GO:0015949=Reactome:REACT_21330, GO:0055086=Reactome:REACT_1698, GO:0001726=PMID:11919189, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000029, GO:0006351=GO_REF:0000037, GO:0030027=PMID:11919189, GO:0006228=GO_REF:0000002, GO:0006183=GO_REF:0000002, GO:0004673=GO_REF:0000003} P22392 Nucleoside diphosphate kinase B protein 20130415 {GO:0005515=IPI, GO:0006241=IEA, GO:0003700=TAS, GO:0045682=IMP, GO:0004550=IDA, GO:0005634=NAS, GO:0009142=IDA, GO:0044281=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0045618=IMP, GO:0007155=TAS, GO:0050679=IMP, GO:0006355=TAS, GO:0043066=IMP, GO:0015949=TAS, GO:0055086=TAS, GO:0001726=IDA, GO:0003677=IEA, GO:0005524=NAS, GO:0006351=IEA, GO:0030027=IDA, GO:0006228=IEA, GO:0006183=IEA, GO:0004673=IEA} CTP biosynthetic process, GTP biosynthetic process, UTP biosynthetic process, cell adhesion, negative regulation of apoptotic process, nucleobase-containing small molecule interconversion, nucleobase-containing small molecule metabolic process, nucleoside triphosphate biosynthetic process, positive regulation of epithelial cell proliferation, positive regulation of keratinocyte differentiation, regulation of epidermis development, regulation of transcription, DNA-dependent, small molecule metabolic process, transcription, DNA-dependent cytosol, lamellipodium, nucleus, ruffle ATP binding, DNA binding, metal ion binding, nucleoside diphosphate kinase activity, protein binding, protein histidine kinase activity, sequence-specific DNA binding transcription factor activity Human UniProtKB:P15531 NME3 PINC UniProtKB {GO:0005739=GO_REF:0000019, GO:0006241=GO_REF:0000002, GO:0006228=GO_REF:0000002, GO:0006183=GO_REF:0000002, GO:0006915=GO_REF:0000037, GO:0004550=GO_REF:0000003, GO:0006917=PMID:7638209, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q13232 Nucleoside diphosphate kinase 3 protein 20030904 {GO:0005739=IEA, GO:0006241=IEA, GO:0006228=IEA, GO:0006183=IEA, GO:0006915=IEA, GO:0004550=IEA, GO:0006917=TAS, GO:0005524=IEA, GO:0046872=IEA} CTP biosynthetic process, GTP biosynthetic process, UTP biosynthetic process, apoptotic process, induction of apoptosis mitochondrion ATP binding, metal ion binding, nucleoside diphosphate kinase activity Human NME4 InterPro UniProtKB {GO:0005515=PMID:23275563, GO:0006241=GO_REF:0000002, GO:0015949=Reactome:REACT_21330, GO:0005743=Reactome:REACT_21362, GO:0004550=GO_REF:0000002, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0006228=GO_REF:0000002, GO:0005739=PMID:9099850, GO:0006183=GO_REF:0000002, GO:0005758=GO_REF:0000039, GO:0009116=PMID:9099850} Q4TT34 Nucleoside diphosphate kinase, mitochondrial protein 20130413 {GO:0005515=IPI, GO:0006241=IEA, GO:0015949=TAS, GO:0005743=TAS, GO:0004550=IEA, GO:0055086=TAS, GO:0044281=TAS, GO:0005524=IEA, GO:0046872=IEA, GO:0006228=IEA, GO:0005739=TAS, GO:0006183=IEA, GO:0005758=IEA, GO:0009116=TAS} CTP biosynthetic process, GTP biosynthetic process, UTP biosynthetic process, nucleobase-containing small molecule interconversion, nucleobase-containing small molecule metabolic process, nucleoside metabolic process, small molecule metabolic process mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrion ATP binding, metal ion binding, nucleoside diphosphate kinase activity, protein binding Human InterPro:IPR001564 NME5 PINC UniProtKB {GO:0006241=GO_REF:0000002, GO:0043066=GO_REF:0000024, GO:0003351=GO_REF:0000019, GO:0007286=GO_REF:0000024, GO:0004550=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0007283=PMID:9742940, GO:0005524=GO_REF:0000002, GO:0006228=GO_REF:0000002, GO:0006183=GO_REF:0000002, GO:0021591=GO_REF:0000019, GO:0009296=GO_REF:0000019, GO:0009116=PMID:9742940} P56597 Nucleoside diphosphate kinase homolog 5 protein 20030904 {GO:0006241=IEA, GO:0043066=ISS, GO:0003351=IEA, GO:0007286=ISS, GO:0004550=IEA, GO:0005575=ND, GO:0007283=TAS, GO:0005524=IEA, GO:0006228=IEA, GO:0006183=IEA, GO:0021591=IEA, GO:0009296=IEA, GO:0009116=TAS} CTP biosynthetic process, GTP biosynthetic process, UTP biosynthetic process, epithelial cilium movement, flagellum assembly, negative regulation of apoptotic process, nucleoside metabolic process, spermatid development, spermatogenesis, ventricular system development cellular_component ATP binding, nucleoside diphosphate kinase activity Human NME6 UniProtKB UniProtKB {GO:0005739=PMID:10618642, GO:0006241=GO_REF:0000002, GO:0006228=GO_REF:0000002, GO:0045839=PMID:10618642, GO:0006183=GO_REF:0000002, GO:0030308=PMID:10618642, GO:0043066=GO_REF:0000029, GO:0006915=GO_REF:0000037, GO:0004550=PMID:10618642, GO:0009142=GO_REF:0000029, GO:0005524=GO_REF:0000029, GO:0046872=GO_REF:0000037} O75414 Nucleoside diphosphate kinase 6 protein 20100504 {GO:0005739=IDA, GO:0006241=IEA, GO:0006228=IEA, GO:0045839=IDA, GO:0006183=IEA, GO:0030308=IDA, GO:0043066=NAS, GO:0006915=IEA, GO:0004550=IDA, GO:0009142=NAS, GO:0005524=NAS, GO:0046872=IEA} CTP biosynthetic process, GTP biosynthetic process, UTP biosynthetic process, apoptotic process, negative regulation of apoptotic process, negative regulation of cell growth, negative regulation of mitosis, nucleoside triphosphate biosynthetic process mitochondrion ATP binding, metal ion binding, nucleoside diphosphate kinase activity Human NME7 UniProtKB UniProtKB {GO:0006241=GO_REF:0000002, GO:0007368=GO_REF:0000019, GO:0005813=PMID:21399614, GO:0003351=GO_REF:0000019, GO:0060830=GO_REF:0000019, GO:0004550=GO_REF:0000003, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0006228=GO_REF:0000002, GO:0006183=GO_REF:0000002, GO:0042073=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0060972=GO_REF:0000019} Q9Y5B8 Nucleoside diphosphate kinase 7 protein 20110517 {GO:0006241=IEA, GO:0007368=IEA, GO:0005813=IDA, GO:0003351=IEA, GO:0060830=IEA, GO:0004550=IEA, GO:0005524=IEA, GO:0046872=IEA, GO:0006228=IEA, GO:0006183=IEA, GO:0042073=IEA, GO:0007420=IEA, GO:0060972=IEA} CTP biosynthetic process, GTP biosynthetic process, UTP biosynthetic process, brain development, ciliary receptor clustering involved in smoothened signaling pathway, determination of left/right symmetry, epithelial cilium movement, intraflagellar transport, left/right pattern formation centrosome ATP binding, metal ion binding, nucleoside diphosphate kinase activity Human NME9 UniProtKB UniProtKB {GO:0006241=GO_REF:0000002, GO:0006228=GO_REF:0000002, GO:0006183=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0004550=GO_REF:0000002, GO:0045454=GO_REF:0000002, GO:0005856=GO_REF:0000039, GO:0005524=GO_REF:0000002} Q86XW9 Thioredoxin domain-containing protein 6 protein 20130413 {GO:0006241=IEA, GO:0006228=IEA, GO:0006183=IEA, GO:0005737=IEA, GO:0004550=IEA, GO:0045454=IEA, GO:0005856=IEA, GO:0005524=IEA} CTP biosynthetic process, GTP biosynthetic process, UTP biosynthetic process, cell redox homeostasis cytoplasm, cytoskeleton ATP binding, nucleoside diphosphate kinase activity Human UniProtKB-SubCell:SL-0090 NMI HPA UniProtKB {GO:0003712=PMID:10779520, GO:0005515=PMID:16919237, GO:0005737=GO_REF:0000052, GO:0006954=PMID:9989503, GO:0006366=PMID:9989503, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0007259=PMID:10597290} Q13287 N-myc-interactor protein 20101115 {GO:0003712=TAS, GO:0005515=IPI, GO:0005737=IDA, GO:0006954=TAS, GO:0006366=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0007259=TAS} JAK-STAT cascade, inflammatory response, transcription from RNA polymerase II promoter cytoplasm, nucleolus, nucleus protein binding, transcription cofactor activity Human NMNAT1 IntAct UniProtKB {GO:0005515=PMID:19478080, GO:0016779=GO_REF:0000002, GO:0009611=GO_REF:0000019, GO:0019674=Reactome:REACT_11088, GO:0006767=Reactome:REACT_11238, GO:0005634=PMID:16118205, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0000309=Reactome:REACT_11237, GO:0006766=Reactome:REACT_11193, GO:0004515=PMID:16118205, GO:0005654=Reactome:REACT_11237, GO:0009435=PMID:16118205} Q9HAN9 Nicotinamide mononucleotide adenylyltransferase 1 protein 20130415 {GO:0005515=IPI, GO:0016779=IEA, GO:0009611=IEA, GO:0019674=TAS, GO:0006767=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0005524=IEA, GO:0000309=TAS, GO:0006766=TAS, GO:0004515=IDA, GO:0005654=TAS, GO:0009435=IC} NAD biosynthetic process, NAD metabolic process, response to wounding, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process nucleoplasm, nucleus ATP binding, nicotinamide-nucleotide adenylyltransferase activity, nicotinate-nucleotide adenylyltransferase activity, nucleotidyltransferase activity, protein binding Human UniProtKB:Q96EB6 NMNAT2 HPA UniProtKB {GO:0005802=GO_REF:0000019, GO:0005794=PMID:16118205, GO:0005770=GO_REF:0000019, GO:0019674=Reactome:REACT_11088, GO:0045202=GO_REF:0000019, GO:0006767=Reactome:REACT_11238, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0000139=Reactome:REACT_11116, GO:0000309=Reactome:REACT_11116, GO:0006766=Reactome:REACT_11193, GO:0004515=PMID:16118205, GO:0009435=GO_REF:0000041} Q9BZQ4 Nicotinamide mononucleotide adenylyltransferase 2 protein 20101115 {GO:0005802=IEA, GO:0005794=IDA, GO:0005770=IEA, GO:0019674=TAS, GO:0045202=IEA, GO:0006767=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0005524=IEA, GO:0005737=IDA, GO:0000139=TAS, GO:0000309=TAS, GO:0006766=TAS, GO:0004515=IDA, GO:0009435=IEA} NAD biosynthetic process, NAD metabolic process, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process Golgi apparatus, Golgi membrane, cytoplasm, late endosome, nucleus, synapse, trans-Golgi network ATP binding, nicotinamide-nucleotide adenylyltransferase activity, nicotinate-nucleotide adenylyltransferase activity Human NMNAT3 Reactome UniProtKB {GO:0005739=PMID:16118205, GO:0000309=Reactome:REACT_11196, GO:0006766=Reactome:REACT_11193, GO:0004515=PMID:16118205, GO:0019674=Reactome:REACT_11088, GO:0009611=GO_REF:0000019, GO:0016779=GO_REF:0000002, GO:0006767=Reactome:REACT_11238, GO:0044281=Reactome:REACT_111217, GO:0009435=GO_REF:0000041, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_11196} Q96T66 Nicotinamide mononucleotide adenylyltransferase 3 protein 20070719 {GO:0005739=IDA, GO:0000309=TAS, GO:0006766=TAS, GO:0004515=IDA, GO:0019674=TAS, GO:0009611=IEA, GO:0016779=IEA, GO:0006767=TAS, GO:0044281=TAS, GO:0009435=IEA, GO:0005524=IEA, GO:0005829=TAS} NAD biosynthetic process, NAD metabolic process, response to wounding, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cytosol, mitochondrion ATP binding, nicotinamide-nucleotide adenylyltransferase activity, nicotinate-nucleotide adenylyltransferase activity, nucleotidyltransferase activity Human NMRAL1 HPA UniProtKB {GO:0048471=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9HBL8 NmrA-like family domain-containing protein 1 protein 20111111 {GO:0048471=IEA, GO:0005730=IDA, GO:0005634=IDA} nucleolus, nucleus, perinuclear region of cytoplasm Human NMS Reactome UniProtKB {GO:0007218=GO_REF:0000037, GO:0005576=Reactome:REACT_25159, GO:0006940=GO_REF:0000002} Q5H8A3 Neuromedin-S protein 20100917 {GO:0007218=IEA, GO:0005576=TAS, GO:0006940=IEA} neuropeptide signaling pathway, regulation of smooth muscle contraction extracellular region Human NMT1 HPA UniProtKB {GO:0022415=Reactome:REACT_6361, GO:0030054=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0009249=PMID:9506952, GO:0006915=Reactome:REACT_578, GO:0004379=GO_REF:0000003, GO:0015629=GO_REF:0000052, GO:0003824=PMID:9506952, GO:0097193=Reactome:REACT_964, GO:0005829=Reactome:REACT_116143, GO:0005737=GO_REF:0000052, GO:1900740=Reactome:REACT_701, GO:0006498=GO_REF:0000029, GO:0016032=Reactome:REACT_6256, GO:0006499=GO_REF:0000029} P30419 Glycylpeptide N-tetradecanoyltransferase 1 protein 20101115 {GO:0022415=TAS, GO:0030054=IDA, GO:0005886=IDA, GO:0009249=TAS, GO:0006915=TAS, GO:0004379=IEA, GO:0015629=IDA, GO:0003824=TAS, GO:0097193=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:1900740=TAS, GO:0006498=NAS, GO:0016032=TAS, GO:0006499=NAS} N-terminal protein lipidation, N-terminal protein myristoylation, apoptotic process, intrinsic apoptotic signaling pathway, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, protein lipoylation, viral reproduction, viral reproductive process actin cytoskeleton, cell junction, cytoplasm, cytosol, plasma membrane catalytic activity, glycylpeptide N-tetradecanoyltransferase activity Human NMT2 HPA UniProtKB {GO:0022415=Reactome:REACT_6361, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0009249=PMID:9506952, GO:0019082=Reactome:REACT_115860, GO:0004379=GO_REF:0000003, GO:0019068=Reactome:REACT_6818, GO:0003824=PMID:9506952, GO:0005829=Reactome:REACT_115774, GO:0046788=Reactome:REACT_115893, GO:0005737=GO_REF:0000052, GO:0016032=Reactome:REACT_6256, GO:0006499=GO_REF:0000002} Q5VUC7 Glycylpeptide N-tetradecanoyltransferase protein 20101115 {GO:0022415=TAS, GO:0005794=IDA, GO:0005886=IDA, GO:0009249=TAS, GO:0019082=TAS, GO:0004379=IEA, GO:0019068=TAS, GO:0003824=TAS, GO:0005829=TAS, GO:0046788=TAS, GO:0005737=IDA, GO:0016032=TAS, GO:0006499=IEA} N-terminal protein myristoylation, egress of virus within host cell, protein lipoylation, viral protein processing, viral reproduction, viral reproductive process, virion assembly Golgi apparatus, cytoplasm, cytosol, plasma membrane catalytic activity, glycylpeptide N-tetradecanoyltransferase activity Human NMU Reactome UniProtKB {GO:0007586=PMID:7619205, GO:0006950=GO_REF:0000019, GO:0005102=PMID:10811630, GO:0005576=Reactome:REACT_25350, GO:0009648=GO_REF:0000019, GO:0006940=PMID:7619205, GO:0001696=GO_REF:0000019, GO:0019233=GO_REF:0000019, GO:0007165=PMID:7619205, GO:0007186=PMID:10811630, GO:0007218=GO_REF:0000019, GO:0045987=GO_REF:0000019, GO:0043195=GO_REF:0000019, GO:0050806=GO_REF:0000019, GO:0042922=GO_REF:0000019, GO:0046887=GO_REF:0000019, GO:0042755=GO_REF:0000019} P48645 Neuromedin-U protein 20100917 {GO:0007586=TAS, GO:0006950=IEA, GO:0005102=TAS, GO:0005576=TAS, GO:0009648=IEA, GO:0006940=TAS, GO:0001696=IEA, GO:0019233=IEA, GO:0007165=TAS, GO:0007186=TAS, GO:0007218=IEA, GO:0045987=IEA, GO:0043195=IEA, GO:0050806=IEA, GO:0042922=IEA, GO:0046887=IEA, GO:0042755=IEA} G-protein coupled receptor signaling pathway, digestion, eating behavior, gastric acid secretion, neuropeptide signaling pathway, photoperiodism, positive regulation of hormone secretion, positive regulation of smooth muscle contraction, positive regulation of synaptic transmission, regulation of smooth muscle contraction, response to stress, sensory perception of pain, signal transduction extracellular region, terminal bouton neuromedin U receptor binding, receptor binding Human NMUR1 Reactome UniProtKB {GO:0006821=PMID:10899166, GO:0019722=PMID:10899166, GO:0005886=Reactome:REACT_25350, GO:0004930=PMID:10899166, GO:0048016=PMID:10899166, GO:0007200=PMID:10899166, GO:0007202=PMID:10899166, GO:0008188=PMID:10811630, GO:0006939=PMID:10899166, GO:0007186=PMID:9782091, GO:0007218=PMID:10899166, GO:0005887=PMID:9782091, GO:0001607=PMID:10899166, GO:0006816=PMID:10899166, GO:0016021=PMID:10899166} Q9HB89 Neuromedin-U receptor 1 protein 20130213 {GO:0006821=IDA, GO:0019722=IDA, GO:0005886=TAS, GO:0004930=TAS, GO:0048016=IDA, GO:0007200=IDA, GO:0007202=IDA, GO:0008188=TAS, GO:0006939=IEP, GO:0007186=TAS, GO:0007218=TAS, GO:0005887=TAS, GO:0001607=IDA, GO:0006816=IDA, GO:0016021=IDA} G-protein coupled receptor signaling pathway, activation of phospholipase C activity, calcium ion transport, calcium-mediated signaling, chloride transport, inositol phosphate-mediated signaling, neuropeptide signaling pathway, phospholipase C-activating G-protein coupled receptor signaling pathway, smooth muscle contraction integral to membrane, integral to plasma membrane, plasma membrane G-protein coupled receptor activity, neuromedin U receptor activity, neuropeptide receptor activity Human NMUR2 Reactome UniProtKB {GO:0043006=PMID:10899166, GO:0007631=PMID:10894543, GO:0019722=PMID:10899166, GO:0005886=Reactome:REACT_25350, GO:0004930=PMID:10894543, GO:0048016=PMID:10899166, GO:0007267=PMID:10894543, GO:0007200=PMID:10899166, GO:0002023=GO_REF:0000019, GO:0006940=PMID:10887190, GO:0005525=PMID:10899166, GO:0007417=PMID:10899166, GO:0007204=PMID:10899166, GO:0007218=PMID:10894543, GO:0042924=PMID:10899166, GO:0001607=PMID:10887190, GO:0005229=PMID:10899166, GO:0048265=GO_REF:0000019, GO:0006816=PMID:10899166, GO:0007625=GO_REF:0000019, GO:0016021=PMID:10899166, GO:0050482=PMID:10887190} Q9GZQ4 Neuromedin-U receptor 2 protein 20100917 {GO:0043006=IDA, GO:0007631=TAS, GO:0019722=NAS, GO:0005886=TAS, GO:0004930=TAS, GO:0048016=IDA, GO:0007267=TAS, GO:0007200=IDA, GO:0002023=IEA, GO:0006940=NAS, GO:0005525=IDA, GO:0007417=IEP, GO:0007204=IDA, GO:0007218=TAS, GO:0042924=IDA, GO:0001607=IDA, GO:0005229=IDA, GO:0048265=IEA, GO:0006816=IDA, GO:0007625=IEA, GO:0016021=IDA, GO:0050482=IDA} activation of phospholipase A2 activity by calcium-mediated signaling, arachidonic acid secretion, calcium ion transport, calcium-mediated signaling, cell-cell signaling, central nervous system development, elevation of cytosolic calcium ion concentration, feeding behavior, grooming behavior, inositol phosphate-mediated signaling, neuropeptide signaling pathway, phospholipase C-activating G-protein coupled receptor signaling pathway, reduction of food intake in response to dietary excess, regulation of smooth muscle contraction, response to pain integral to membrane, plasma membrane G-protein coupled receptor activity, GTP binding, intracellular calcium activated chloride channel activity, neuromedin U binding, neuromedin U receptor activity Human NNAT PINC UniProtKB {GO:0032880=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0009249=PMID:8813377, GO:0007420=GO_REF:0000019, GO:0030182=GO_REF:0000019, GO:0006810=PMID:8813377, GO:0032024=GO_REF:0000019, GO:0009749=GO_REF:0000019} Q16517 Neuronatin protein 20030904 {GO:0032880=IEA, GO:0005737=IEA, GO:0009249=TAS, GO:0007420=IEA, GO:0030182=IEA, GO:0006810=TAS, GO:0032024=IEA, GO:0009749=IEA} brain development, neuron differentiation, positive regulation of insulin secretion, protein lipoylation, regulation of protein localization, response to glucose stimulus, transport cytoplasm Human NNMT Reactome UniProtKB {GO:0008112=GO_REF:0000003, GO:0006805=Reactome:REACT_13433, GO:0042493=GO_REF:0000019, GO:0031100=GO_REF:0000019, GO:0008168=GO_REF:0000002, GO:0010243=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0032259=Reactome:REACT_6946, GO:0005829=Reactome:REACT_6930} P40261 Nicotinamide N-methyltransferase protein 20130301 {GO:0008112=IEA, GO:0006805=TAS, GO:0042493=IEA, GO:0031100=IEA, GO:0008168=IEA, GO:0010243=IEA, GO:0044281=TAS, GO:0032259=TAS, GO:0005829=TAS} methylation, organ regeneration, response to drug, response to organic nitrogen, small molecule metabolic process, xenobiotic metabolic process cytosol methyltransferase activity, nicotinamide N-methyltransferase activity Human NNT LIFEdb UniProtKB {GO:0050661=PMID:10673423, GO:0006099=Reactome:REACT_1785, GO:0072593=PMID:22634753, GO:0005743=Reactome:REACT_21342, GO:0008746=Reactome:REACT_21342, GO:0044281=Reactome:REACT_111217, GO:0008750=GO_REF:0000003, GO:0005739=GO_REF:0000054, GO:0005746=PMID:10673423, GO:0051287=PMID:10673423, GO:0003957=PMID:9524818, GO:0016491=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0015992=PMID:10673423, GO:0055114=PMID:10673423} Q13423 NAD(P) transhydrogenase, mitochondrial protein 20100607 {GO:0050661=IDA, GO:0006099=TAS, GO:0072593=IMP, GO:0005743=TAS, GO:0008746=EXP, GO:0044281=TAS, GO:0008750=IEA, GO:0005739=IDA, GO:0005746=TAS, GO:0051287=TAS, GO:0003957=TAS, GO:0016491=IEA, GO:0016021=IEA, GO:0015992=TAS, GO:0055114=TAS} oxidation-reduction process, proton transport, reactive oxygen species metabolic process, small molecule metabolic process, tricarboxylic acid cycle integral to membrane, mitochondrial inner membrane, mitochondrial respiratory chain, mitochondrion NAD binding, NAD(P)+ transhydrogenase (AB-specific) activity, NAD(P)+ transhydrogenase (B-specific) activity, NAD(P)+ transhydrogenase activity, NADP binding, oxidoreductase activity Human NOA1 GOC UniProtKB {GO:0006184=GO_REF:0000033, GO:0005515=PMID:19103604, GO:0032543=GO_REF:0000024, GO:0031314=PMID:19103604, GO:0042254=GO_REF:0000033, GO:0003924=GO_REF:0000033, GO:0006915=GO_REF:0000037, GO:0005525=PMID:19103604, GO:0043457=PMID:19103604, GO:0010941=PMID:19103604} Q8NC60 Nitric oxide-associated protein 1 protein 20130413 {GO:0006184=IBA, GO:0005515=IPI, GO:0032543=ISS, GO:0031314=IDA, GO:0042254=IBA, GO:0003924=IBA, GO:0006915=IEA, GO:0005525=IDA, GO:0043457=IMP, GO:0010941=IMP} GTP catabolic process, apoptotic process, mitochondrial translation, regulation of cell death, regulation of cellular respiration, ribosome biogenesis extrinsic to mitochondrial inner membrane GTP binding, GTPase activity, protein binding Human PANTHER:PTN000119716 NOB1 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039, GO:0046872=GO_REF:0000037} Q9ULX3 RNA-binding protein NOB1 protein 20130413 {GO:0005634=IEA, GO:0046872=IEA} nucleus metal ion binding Human UniProtKB-SubCell:SL-0191 NOC2L HPA UniProtKB {GO:0005515=PMID:21078624, GO:0043066=PMID:16322561, GO:0003714=PMID:16322561, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0031491=PMID:16322561, GO:0005634=GO_REF:0000054, GO:0000122=PMID:20959462, GO:0035067=PMID:16322561, GO:0006351=GO_REF:0000037, GO:0032066=PMID:20123734, GO:0042393=PMID:16322561, GO:0034644=PMID:20959462, GO:0003682=PMID:16322561, GO:0002903=PMID:20959462, GO:0070491=PMID:16322561, GO:0005654=PMID:20123734} Q9Y3T9 Nucleolar complex protein 2 homolog protein 20111111 {GO:0005515=IPI, GO:0043066=IMP, GO:0003714=IDA, GO:0005730=IDA, GO:0006915=IEA, GO:0031491=IDA, GO:0005634=IDA, GO:0000122=IDA, GO:0035067=IDA, GO:0006351=IEA, GO:0032066=IDA, GO:0042393=IDA, GO:0034644=IDA, GO:0003682=IDA, GO:0002903=IMP, GO:0070491=IDA, GO:0005654=IDA} apoptotic process, cellular response to UV, negative regulation of B cell apoptotic process, negative regulation of apoptotic process, negative regulation of histone acetylation, negative regulation of transcription from RNA polymerase II promoter, nucleolus to nucleoplasm transport, transcription, DNA-dependent nucleolus, nucleoplasm, nucleus chromatin binding, histone binding, nucleosome binding, protein binding, repressing transcription factor binding, transcription corepressor activity Human NOC3L UniProtKB UniProtKB {GO:0016607=GO_REF:0000039, GO:0005730=GO_REF:0000039, GO:0045444=GO_REF:0000019} Q8WTT2 Nucleolar complex protein 3 homolog protein 20130413 {GO:0016607=IEA, GO:0005730=IEA, GO:0045444=IEA} fat cell differentiation nuclear speck, nucleolus Human UniProtKB-SubCell:SL-0186 NOC4L IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0031965=GO_REF:0000039, GO:0006364=GO_REF:0000024, GO:0042254=GO_REF:0000002, GO:0005730=GO_REF:0000024, GO:0016021=GO_REF:0000037} Q9BVI4 Nucleolar complex protein 4 homolog protein 20130415 {GO:0005515=IPI, GO:0031965=IEA, GO:0006364=ISS, GO:0042254=IEA, GO:0005730=ISS, GO:0016021=IEA} rRNA processing, ribosome biogenesis integral to membrane, nuclear membrane, nucleolus protein binding Human UniProtKB:Q8N6Y0 NOD1 BHF-UCL UniProtKB {GO:0032755=GO_REF:0000019, GO:0005515=PMID:19337385, GO:0042228=PMID:15653568, GO:0050830=GO_REF:0000019, GO:0046330=GO_REF:0000019, GO:0051403=Reactome:REACT_21308, GO:0051259=PMID:15967716, GO:0042803=PMID:18186648, GO:0042802=PMID:18186648, GO:0005622=GO_REF:0000002, GO:0002756=Reactome:REACT_6809, GO:0002755=Reactome:REACT_27215, GO:0009595=PMID:15967716, GO:0070374=GO_REF:0000019, GO:0043123=PMID:10329646, GO:0042742=PMID:15653568, GO:0050700=PMID:10329646, GO:0038124=Reactome:REACT_8006, GO:0032760=GO_REF:0000019, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0042834=PMID:15967716, GO:0006952=PMID:15967716, GO:0002224=Reactome:REACT_9020, GO:0008656=PMID:10329646, GO:0045087=Reactome:REACT_6802, GO:0034166=Reactome:REACT_9027, GO:0035666=Reactome:REACT_25281, GO:0016045=PMID:15653568, GO:0034162=Reactome:REACT_9047, GO:0034142=Reactome:REACT_6894, GO:0070423=Reactome:REACT_75776, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_75924, GO:0035556=PMID:15653568, GO:0016323=PMID:19043560, GO:0000187=Reactome:REACT_21399, GO:0005737=PMID:10329646, GO:0016324=GO_REF:0000039, GO:0006954=PMID:15967716, GO:0051092=Reactome:REACT_21281, GO:0034138=Reactome:REACT_6783, GO:0006919=PMID:10329646, GO:0007254=Reactome:REACT_21368, GO:0006915=PMID:10329646, GO:0042981=GO_REF:0000002, GO:0006917=PMID:10329646, GO:0002606=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0007165=PMID:15967716, GO:0034146=Reactome:REACT_9061} Q9Y239 Nucleotide-binding oligomerization domain-containing protein 1 protein 20110124 {GO:0032755=IEA, GO:0005515=IPI, GO:0042228=IDA, GO:0050830=IEA, GO:0046330=IEA, GO:0051403=TAS, GO:0051259=TAS, GO:0042803=IPI, GO:0042802=IPI, GO:0005622=IEA, GO:0002756=TAS, GO:0002755=TAS, GO:0009595=TAS, GO:0070374=IEA, GO:0043123=IDA, GO:0042742=IDA, GO:0050700=IDA, GO:0038124=TAS, GO:0032760=IEA, GO:0038123=TAS, GO:0034134=TAS, GO:0042834=TAS, GO:0006952=TAS, GO:0002224=TAS, GO:0008656=TAS, GO:0045087=TAS, GO:0034166=TAS, GO:0035666=TAS, GO:0016045=IDA, GO:0034162=TAS, GO:0034142=TAS, GO:0070423=TAS, GO:0035872=TAS, GO:0005829=TAS, GO:0035556=IDA, GO:0016323=IDA, GO:0000187=TAS, GO:0005737=IDA, GO:0016324=IEA, GO:0006954=TAS, GO:0051092=TAS, GO:0034138=TAS, GO:0006919=IDA, GO:0007254=TAS, GO:0006915=TAS, GO:0042981=IEA, GO:0006917=IDA, GO:0002606=ISS, GO:0005524=IEA, GO:0007165=TAS, GO:0034146=TAS} JNK cascade, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, activation of MAPK activity, activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, defense response, defense response to Gram-positive bacterium, defense response to bacterium, detection of bacterium, detection of biotic stimulus, induction of apoptosis, inflammatory response, innate immune response, interleukin-8 biosynthetic process, intracellular signal transduction, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, nucleotide-binding oligomerization domain containing signaling pathway, positive regulation of ERK1 and ERK2 cascade, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of JNK cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of dendritic cell antigen processing and presentation, positive regulation of interleukin-6 production, positive regulation of tumor necrosis factor production, protein oligomerization, regulation of apoptotic process, signal transduction, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway apical plasma membrane, basolateral plasma membrane, cytoplasm, cytosol, intracellular ATP binding, CARD domain binding, cysteine-type endopeptidase activator activity involved in apoptotic process, identical protein binding, peptidoglycan binding, protein binding, protein homodimerization activity Human UniProtKB:O43353 NOD2 BHF-UCL UniProtKB {GO:0032755=PMID:16414084, GO:0005515=PMID:19337385, GO:0051353=GO_REF:0000024, GO:0050830=GO_REF:0000019, GO:0046330=PMID:17187069, GO:0050731=GO_REF:0000019, GO:0002710=GO_REF:0000019, GO:0051403=Reactome:REACT_21308, GO:0051259=PMID:15967716, GO:0002756=Reactome:REACT_6809, GO:0032500=PMID:15998797, GO:0043552=GO_REF:0000024, GO:0002755=Reactome:REACT_27215, GO:0009595=PMID:15967716, GO:0032496=GO_REF:0000019, GO:0032498=PMID:15998797, GO:0070374=GO_REF:0000024, GO:0043123=PMID:12527755, GO:0044130=GO_REF:0000019, GO:0032689=GO_REF:0000019, GO:0042742=PMID:15653568, GO:0050679=GO_REF:0000024, GO:0045747=GO_REF:0000024, GO:0050700=PMID:11087742, GO:0002367=PMID:16260731, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0032760=PMID:21040358, GO:0019901=PMID:15075345, GO:0009986=PMID:16714539, GO:0046645=GO_REF:0000024, GO:0034134=Reactome:REACT_7980, GO:0042834=PMID:15998797, GO:0032720=GO_REF:0000019, GO:0006952=PMID:15967716, GO:0070431=PMID:12527755, GO:0060585=GO_REF:0000024, GO:0002224=Reactome:REACT_9020, GO:0002227=GO_REF:0000019, GO:0052033=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0050871=PMID:20844241, GO:0090022=GO_REF:0000019, GO:0002830=PMID:21172192, GO:0035666=Reactome:REACT_25281, GO:0034166=Reactome:REACT_9027, GO:0019899=PMID:15753091, GO:0016045=PMID:15653568, GO:0034162=Reactome:REACT_9047, GO:0008284=GO_REF:0000019, GO:0034142=Reactome:REACT_6894, GO:0002862=GO_REF:0000019, GO:0032733=GO_REF:0000024, GO:0005886=PMID:15998797, GO:0032731=PMID:21040358, GO:0035419=GO_REF:0000024, GO:0070423=Reactome:REACT_75776, GO:0032874=PMID:17187069, GO:0032735=GO_REF:0000019, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_75924, GO:0035556=PMID:15653568, GO:0000187=Reactome:REACT_21399, GO:0005737=PMID:15967716, GO:0050766=GO_REF:0000019, GO:0002925=GO_REF:0000019, GO:0002732=GO_REF:0000019, GO:0051092=Reactome:REACT_21281, GO:0008180=PMID:17337451, GO:0050718=PMID:15107016, GO:0002381=GO_REF:0000019, GO:0002282=GO_REF:0000019, GO:0034138=Reactome:REACT_6783, GO:2000363=GO_REF:0000024, GO:0034136=GO_REF:0000019, GO:0032703=GO_REF:0000019, GO:0032740=PMID:17919942, GO:0007584=GO_REF:0000019, GO:0050727=PMID:11385577, GO:0007254=Reactome:REACT_21368, GO:0032088=GO_REF:0000019, GO:0042981=GO_REF:0000002, GO:0002606=GO_REF:0000024, GO:2000110=GO_REF:0000024, GO:0031982=PMID:15998797, GO:0005524=GO_REF:0000037, GO:0032701=GO_REF:0000019, GO:0006965=GO_REF:0000019, GO:0032695=GO_REF:0000019, GO:0002253=GO_REF:0000019, GO:0071608=GO_REF:0000019, GO:0032495=PMID:16414084, GO:0051770=GO_REF:0000024, GO:0034146=Reactome:REACT_9061, GO:0043330=GO_REF:0000019, GO:0071224=GO_REF:0000019} Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 protein 20110124 {GO:0032755=IDA, GO:0005515=IPI, GO:0051353=ISS, GO:0050830=IEA, GO:0046330=IDA, GO:0050731=IEA, GO:0002710=IEA, GO:0051403=TAS, GO:0051259=TAS, GO:0002756=TAS, GO:0032500=IDA, GO:0043552=ISS, GO:0002755=TAS, GO:0009595=TAS, GO:0032496=IEA, GO:0032498=IDA, GO:0070374=ISS, GO:0043123=IDA, GO:0044130=IEA, GO:0032689=IEA, GO:0042742=IDA, GO:0050679=ISS, GO:0045747=ISS, GO:0050700=IPI, GO:0002367=IMP, GO:0038124=TAS, GO:0038123=TAS, GO:0032760=IMP, GO:0019901=IPI, GO:0009986=IDA, GO:0046645=ISS, GO:0034134=TAS, GO:0042834=IDA, GO:0032720=IEA, GO:0006952=TAS, GO:0070431=IDA, GO:0060585=ISS, GO:0002224=TAS, GO:0002227=IEA, GO:0052033=IEA, GO:0045087=TAS, GO:0050871=IDA, GO:0090022=IEA, GO:0002830=IMP, GO:0035666=TAS, GO:0034166=TAS, GO:0019899=IPI, GO:0016045=IDA, GO:0034162=TAS, GO:0008284=IEA, GO:0034142=TAS, GO:0002862=IEA, GO:0032733=ISS, GO:0005886=IDA, GO:0032731=IMP, GO:0035419=ISS, GO:0070423=TAS, GO:0032874=IDA, GO:0032735=IEA, GO:0035872=TAS, GO:0005829=TAS, GO:0035556=IDA, GO:0000187=TAS, GO:0005737=TAS, GO:0050766=IEA, GO:0002925=IEA, GO:0002732=IEA, GO:0051092=TAS, GO:0008180=IDA, GO:0050718=IDA, GO:0002381=IEA, GO:0002282=IEA, GO:0034138=TAS, GO:2000363=ISS, GO:0034136=IEA, GO:0032703=IEA, GO:0032740=IMP, GO:0007584=IEA, GO:0050727=IC, GO:0007254=TAS, GO:0032088=IEA, GO:0042981=IEA, GO:0002606=ISS, GO:2000110=ISS, GO:0031982=IDA, GO:0005524=IEA, GO:0032701=IEA, GO:0006965=IEA, GO:0032695=IEA, GO:0002253=IEA, GO:0071608=IEA, GO:0032495=IDA, GO:0051770=ISS, GO:0034146=TAS, GO:0043330=IEA, GO:0071224=IEA} JNK cascade, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, activation of MAPK activity, activation of MAPK activity involved in innate immune response, activation of immune response, cellular response to peptidoglycan, cytokine production involved in immune response, defense response, defense response to Gram-positive bacterium, defense response to bacterium, detection of bacterium, detection of biotic stimulus, detection of muramyl dipeptide, immunoglobulin production involved in immunoglobulin mediated immune response, innate immune response, innate immune response in mucosa, intracellular signal transduction, macrophage inflammatory protein-1 alpha production, microglial cell activation involved in immune response, negative regulation of NF-kappaB transcription factor activity, negative regulation of T cell mediated immunity, negative regulation of growth of symbiont in host, negative regulation of inflammatory response to antigenic stimulus, negative regulation of interferon-gamma production, negative regulation of interleukin-12 production, negative regulation of interleukin-18 production, negative regulation of interleukin-2 production, negative regulation of macrophage apoptotic process, negative regulation of toll-like receptor 2 signaling pathway, negative regulation of tumor necrosis factor production, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, nucleotide-binding oligomerization domain containing 2 signaling pathway, nucleotide-binding oligomerization domain containing signaling pathway, pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response, positive regulation of B cell activation, positive regulation of ERK1 and ERK2 cascade, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of JNK cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of Notch signaling pathway, positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria, positive regulation of cell proliferation, positive regulation of dendritic cell antigen processing and presentation, positive regulation of dendritic cell cytokine production, positive regulation of epithelial cell proliferation, positive regulation of gamma-delta T cell activation, positive regulation of humoral immune response mediated by circulating immunoglobulin, positive regulation of interleukin-1 beta production, positive regulation of interleukin-1 beta secretion, positive regulation of interleukin-10 production, positive regulation of interleukin-12 production, positive regulation of interleukin-17 production, positive regulation of interleukin-6 production, positive regulation of nitric-oxide synthase biosynthetic process, positive regulation of oxidoreductase activity, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of phagocytosis, positive regulation of phosphatidylinositol 3-kinase activity, positive regulation of prostaglandin-E synthase activity, positive regulation of prostaglandin-endoperoxide synthase activity, positive regulation of stress-activated MAPK cascade, positive regulation of tumor necrosis factor production, positive regulation of type 2 immune response, protein oligomerization, regulation of apoptotic process, regulation of inflammatory response, regulation of neutrophil chemotaxis, response to exogenous dsRNA, response to lipopolysaccharide, response to muramyl dipeptide, response to nutrient, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway cell surface, cytoplasm, cytosol, plasma membrane, signalosome, vesicle ATP binding, CARD domain binding, enzyme binding, muramyl dipeptide binding, peptidoglycan binding, protein binding, protein kinase binding Human UniProtKB:O43353 NOG BHF-UCL UniProtKB {GO:0071773=GO_REF:0000019, GO:0060044=PMID:10780858, GO:0051216=GO_REF:0000037, GO:0048706=PMID:10080184, GO:0060302=PMID:8752214, GO:0060676=GO_REF:0000019, GO:0005615=PMID:11562478, GO:2000313=PMID:8582276, GO:0042803=PMID:11562478, GO:0090193=GO_REF:0000024, GO:0050679=GO_REF:0000019, GO:0001706=GO_REF:0000019, GO:0030336=PMID:20675382, GO:0001707=GO_REF:0000019, GO:0001843=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0030509=Reactome:REACT_12034, GO:0001701=GO_REF:0000019, GO:0001649=PMID:10780858, GO:0061053=GO_REF:0000019, GO:0008045=GO_REF:0000019, GO:0001501=PMID:10080184, GO:0060825=PMID:8582276, GO:0019955=PMID:8752214, GO:0060272=PMID:16151340, GO:0042060=PMID:10780858, GO:0060173=PMID:10080184, GO:0042733=PMID:10080184, GO:0021533=PMID:8582276, GO:0021510=GO_REF:0000019, GO:0060425=GO_REF:0000019, GO:0021983=GO_REF:0000019, GO:0001839=GO_REF:0000019, GO:0001837=PMID:10780858, GO:0009953=PMID:7666191, GO:0060394=PMID:15539560, GO:0048570=GO_REF:0000019, GO:0030514=PMID:15539560, GO:0045944=GO_REF:0000019, GO:0042474=PMID:10080184, GO:0090090=PMID:15539560, GO:0035019=PMID:17889703, GO:0090190=GO_REF:0000024, GO:0048318=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0005576=Reactome:REACT_12026, GO:0007399=PMID:7666191, GO:0048712=PMID:10780858, GO:0045668=PMID:20675382, GO:0060325=GO_REF:0000019, GO:0060513=GO_REF:0000019, GO:0061037=GO_REF:0000019} Q13253 Noggin protein 20110118 {GO:0071773=IEA, GO:0060044=ISS, GO:0051216=IEA, GO:0048706=IMP, GO:0060302=IPI, GO:0060676=IEA, GO:0005615=IDA, GO:2000313=IMP, GO:0042803=IDA, GO:0090193=ISS, GO:0050679=IEA, GO:0001706=IEA, GO:0030336=IDA, GO:0001707=IEA, GO:0001843=IEA, GO:0000122=IEA, GO:0030509=TAS, GO:0001701=IEA, GO:0001649=ISS, GO:0061053=IEA, GO:0008045=IEA, GO:0001501=TAS, GO:0060825=IMP, GO:0019955=IPI, GO:0060272=IMP, GO:0042060=ISS, GO:0060173=IMP, GO:0042733=IMP, GO:0021533=IMP, GO:0021510=IEA, GO:0060425=IEA, GO:0021983=IEA, GO:0001839=IEA, GO:0001837=ISS, GO:0009953=IDA, GO:0060394=IDA, GO:0048570=IEA, GO:0030514=IDA, GO:0045944=IEA, GO:0042474=IMP, GO:0090090=IDA, GO:0035019=IMP, GO:0090190=ISS, GO:0048318=IEA, GO:0043066=IEA, GO:0005576=TAS, GO:0007399=TAS, GO:0048712=ISS, GO:0045668=IDA, GO:0060325=IEA, GO:0060513=IEA, GO:0061037=IEA} BMP signaling pathway, axial mesoderm development, cartilage development, cell differentiation in hindbrain, cellular response to BMP stimulus, dorsal/ventral pattern formation, embryonic digit morphogenesis, embryonic skeletal joint morphogenesis, embryonic skeletal system development, endoderm formation, epithelial to mesenchymal transition, face morphogenesis, fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation, in utero embryonic development, limb development, lung morphogenesis, mesoderm formation, middle ear morphogenesis, motor neuron axon guidance, negative regulation of BMP signaling pathway, negative regulation of apoptotic process, negative regulation of astrocyte differentiation, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cardiac muscle cell proliferation, negative regulation of cartilage development, negative regulation of cell migration, negative regulation of cytokine activity, negative regulation of osteoblast differentiation, negative regulation of pathway-restricted SMAD protein phosphorylation, negative regulation of transcription from RNA polymerase II promoter, nervous system development, neural plate morphogenesis, neural tube closure, notochord morphogenesis, osteoblast differentiation, pituitary gland development, positive regulation of branching involved in ureteric bud morphogenesis, positive regulation of epithelial cell proliferation, positive regulation of glomerulus development, positive regulation of transcription from RNA polymerase II promoter, prostatic bud formation, regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation, skeletal system development, somatic stem cell maintenance, somite development, spinal cord development, ureteric bud formation, wound healing extracellular region, extracellular space cytokine binding, protein homodimerization activity Human NOL10 UniProtKB UniProtKB {GO:0005730=GO_REF:0000039, GO:0005634=GO_REF:0000002} Q9BSC4 Nucleolar protein 10 protein 20130413 {GO:0005730=IEA, GO:0005634=IEA} nucleolus, nucleus Human UniProtKB-SubCell:SL-0188 NOL11 HPA UniProtKB {GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000002} Q9H8H0 Nucleolar protein 11 protein 20100326 {GO:0005730=IDA, GO:0005634=IEA} nucleolus, nucleus Human NOL12 UniProtKB UniProtKB {GO:0005730=GO_REF:0000039, GO:0019843=GO_REF:0000019} Q9UGY1 Nucleolar protein 12 protein 20130413 {GO:0005730=IEA, GO:0019843=IEA} nucleolus rRNA binding Human UniProtKB-SubCell:SL-0188 NOL3 IntAct UniProtKB {GO:0006397=GO_REF:0000037, GO:0008380=GO_REF:0000037, GO:0005515=PMID:18245485, GO:0043066=PMID:9560245, GO:0003723=PMID:10196175, GO:0005730=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0042981=GO_REF:0000002, GO:0005829=PMID:10196175, GO:0042802=PMID:16189514, GO:0005622=GO_REF:0000002, GO:0005739=GO_REF:0000019, GO:0016528=GO_REF:0000019} O60936 Nucleolar protein 3 protein 20130415 {GO:0006397=IEA, GO:0008380=IEA, GO:0005515=IPI, GO:0043066=TAS, GO:0003723=TAS, GO:0005730=IEA, GO:0006915=IEA, GO:0042981=IEA, GO:0005829=TAS, GO:0042802=IPI, GO:0005622=IEA, GO:0005739=IEA, GO:0016528=IEA} RNA splicing, apoptotic process, mRNA processing, negative regulation of apoptotic process, regulation of apoptotic process cytosol, intracellular, mitochondrion, nucleolus, sarcoplasm RNA binding, identical protein binding, protein binding Human UniProtKB:O60936 NOL4 PINC UniProtKB {GO:0003723=PMID:9813152, GO:0005730=GO_REF:0000039} O94818 Nucleolar protein 4 protein 20030904 {GO:0003723=TAS, GO:0005730=IEA} nucleolus RNA binding Human NOL6 UniProtKB UniProtKB {GO:0000794=PMID:11895476, GO:0006364=GO_REF:0000024, GO:0003723=PMID:11895476, GO:0005730=GO_REF:0000024} Q9H6R4 Nucleolar protein 6 protein 20091117 {GO:0000794=ISS, GO:0006364=ISS, GO:0003723=ISS, GO:0005730=ISS} rRNA processing condensed nuclear chromosome, nucleolus RNA binding Human UniProtKB:P53254 NOL7 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005730=GO_REF:0000052} Q9UMY1 Nucleolar protein 7 protein 20101115 {GO:0005739=IDA, GO:0005730=IDA} mitochondrion, nucleolus Human NOL8 HPA UniProtKB {GO:0006260=PMID:14660641, GO:0005515=PMID:14660641, GO:0005737=GO_REF:0000052, GO:0000166=GO_REF:0000002, GO:0030307=PMID:14660641, GO:0006364=PMID:16963496, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002} Q76FK4 Nucleolar protein 8 protein 20111111 {GO:0006260=IMP, GO:0005515=IPI, GO:0005737=IDA, GO:0000166=IEA, GO:0030307=IMP, GO:0006364=IMP, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA} DNA replication, positive regulation of cell growth, rRNA processing cytoplasm, nucleolus, nucleus RNA binding, nucleic acid binding, nucleotide binding, protein binding Human NOL9 UniProtKB UniProtKB {GO:0051731=PMID:21063389, GO:0000460=PMID:21063389, GO:0003723=GO_REF:0000037, GO:0005730=PMID:21063389, GO:0005524=PMID:21063389} Q5SY16 Polynucleotide 5'-hydroxyl-kinase NOL9 protein 20101123 {GO:0051731=IDA, GO:0000460=IMP, GO:0003723=IEA, GO:0005730=TAS, GO:0005524=TAS} maturation of 5.8S rRNA nucleolus ATP binding, RNA binding, polynucleotide 5'-hydroxyl-kinase activity Human NOLC1 HPA UniProtKB {GO:0005515=PMID:22190034, GO:0007000=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0007067=PMID:7657714, GO:0007049=PMID:7657714, GO:0015030=GO_REF:0000019, GO:0006364=PMID:7657714, GO:0005730=GO_REF:0000052, GO:0005525=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q14978 Nucleolar and coiled-body phosphoprotein 1 protein 20110516 {GO:0005515=IPI, GO:0007000=IEA, GO:0005737=IDA, GO:0007067=TAS, GO:0007049=TAS, GO:0015030=IEA, GO:0006364=TAS, GO:0005730=IDA, GO:0005525=IEA, GO:0005524=IEA} cell cycle, mitosis, nucleolus organization, rRNA processing Cajal body, cytoplasm, nucleolus ATP binding, GTP binding, protein binding Human NOM1 UniProtKB UniProtKB {GO:0005515=PMID:17965019, GO:0008150=GO_REF:0000015, GO:0016070=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0005730=PMID:17965019, GO:0003677=GO_REF:0000002} Q5C9Z4 Nucleolar MIF4G domain-containing protein 1 protein 20091104 {GO:0005515=IPI, GO:0008150=ND, GO:0016070=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0003677=IEA} RNA metabolic process, biological_process nucleolus DNA binding, RNA binding, protein binding Human UniProtKB:P36873 NOMO1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0030246=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} Q15155 Nodal modulator 1 protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0030246=IEA, GO:0005575=ND, GO:0016021=IEA} biological_process cellular_component, integral to membrane carbohydrate binding, molecular_function Human NOMO2 UniProtKB UniProtKB {GO:0005515=PMID:17261586, GO:0005789=PMID:17261586, GO:0030246=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q5JPE7 Nodal modulator 2 protein 20100507 {GO:0005515=IPI, GO:0005789=IDA, GO:0030246=IEA, GO:0016021=IEA} endoplasmic reticulum membrane, integral to membrane carbohydrate binding, protein binding Human NOMO3 UniProtKB UniProtKB {GO:0030246=GO_REF:0000002, GO:0016021=GO_REF:0000037} P69849 Nodal modulator 3 protein 20130413 {GO:0030246=IEA, GO:0016021=IEA} integral to membrane carbohydrate binding Human UniProtKB-KW:KW-0812 NONO BHF-UCL UniProtKB {GO:0006397=GO_REF:0000037, GO:0008380=GO_REF:0000037, GO:0005515=PMID:19874820, GO:0006355=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0005634=PMID:9360842, GO:0006310=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0016363=PMID:19874820, GO:0006351=GO_REF:0000037, GO:0042382=PMID:19217333, GO:0006281=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0016607=GO_REF:0000039} Q15233 Non-POU domain-containing octamer-binding protein protein 20100107 {GO:0006397=IEA, GO:0008380=IEA, GO:0005515=IPI, GO:0006355=IEA, GO:0003723=IEA, GO:0005730=IEA, GO:0005634=TAS, GO:0006310=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0016363=IDA, GO:0006351=IEA, GO:0042382=IDA, GO:0006281=IEA, GO:0000166=IEA, GO:0016607=IEA} DNA recombination, DNA repair, RNA splicing, mRNA processing, regulation of transcription, DNA-dependent, transcription, DNA-dependent nuclear matrix, nuclear speck, nucleolus, nucleus, paraspeckles DNA binding, RNA binding, nucleic acid binding, nucleotide binding, protein binding Human NOP10 UniProtKB UniProtKB {GO:0005515=PMID:16601202, GO:0015030=GO_REF:0000039, GO:0006364=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0005732=PMID:9843512, GO:0001522=PMID:9843512} Q9NPE3 H/ACA ribonucleoprotein complex subunit 3 protein 20080201 {GO:0005515=IPI, GO:0015030=IEA, GO:0006364=IEA, GO:0005730=IEA, GO:0005732=TAS, GO:0001522=NAS} pseudouridine synthesis, rRNA processing Cajal body, nucleolus, small nucleolar ribonucleoprotein complex protein binding Human UniProtKB:Q96HR8 NOP14 UniProtKB UniProtKB {GO:0005739=GO_REF:0000024, GO:0000462=GO_REF:0000024, GO:0000472=GO_REF:0000024, GO:0030515=GO_REF:0000024, GO:0006364=GO_REF:0000024, GO:0032040=GO_REF:0000024, GO:0005730=GO_REF:0000024, GO:0000480=GO_REF:0000024, GO:0042274=GO_REF:0000024, GO:0000447=GO_REF:0000024, GO:0030692=GO_REF:0000024, GO:0030686=GO_REF:0000024} P78316 Nucleolar protein 14 protein 20091116 {GO:0005739=ISS, GO:0000462=ISS, GO:0000472=ISS, GO:0030515=ISS, GO:0006364=ISS, GO:0032040=ISS, GO:0005730=ISS, GO:0000480=ISS, GO:0042274=ISS, GO:0000447=ISS, GO:0030692=ISS, GO:0030686=ISS} endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA), maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), rRNA processing, ribosomal small subunit biogenesis 90S preribosome, Noc4p-Nop14p complex, mitochondrion, nucleolus, small-subunit processome snoRNA binding Human UniProtKB:Q99207 NOP16 HPA UniProtKB {GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0043231=GO_REF:0000052} Q9Y3C1 Nucleolar protein 16 protein 20110516 {GO:0005730=IDA, GO:0005634=IDA, GO:0043231=IDA} intracellular membrane-bounded organelle, nucleolus, nucleus Human NOP2 HPA UniProtKB {GO:0005515=PMID:12080348, GO:0008284=PMID:1394192, GO:0006364=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0008168=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0008757=GO_REF:0000002, GO:0005634=GO_REF:0000052} P46087 Putative ribosomal RNA methyltransferase NOP2 protein 20110516 {GO:0005515=IPI, GO:0008284=TAS, GO:0006364=IEA, GO:0003723=IEA, GO:0008168=IEA, GO:0005730=IDA, GO:0008757=IEA, GO:0005634=IDA} positive regulation of cell proliferation, rRNA processing nucleolus, nucleus RNA binding, S-adenosylmethionine-dependent methyltransferase activity, methyltransferase activity, protein binding Human NOP56 BHF-UCL UniProtKB {GO:0005515=PMID:17636026, GO:0008219=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0030515=PMID:17636026, GO:0031428=PMID:17636026, GO:0006364=PMID:9372940, GO:0003723=PMID:9372940, GO:0070761=PMID:17636026, GO:0005730=PMID:9372940, GO:0005732=PMID:17636026} O00567 Nucleolar protein 56 protein 20090629 {GO:0005515=IPI, GO:0008219=IEA, GO:0005737=IEA, GO:0030515=IDA, GO:0031428=NAS, GO:0006364=TAS, GO:0003723=TAS, GO:0070761=IDA, GO:0005730=TAS, GO:0005732=IDA} cell death, rRNA processing box C/D snoRNP complex, cytoplasm, nucleolus, pre-snoRNP complex, small nucleolar ribonucleoprotein complex RNA binding, protein binding, snoRNA binding Human NOP58 HPA UniProtKB {GO:0005515=PMID:17636026, GO:0005737=GO_REF:0000052, GO:0015030=PMID:16687569, GO:0030515=PMID:17636026, GO:0031428=PMID:17636026, GO:0006364=PMID:10925205, GO:0070761=PMID:17636026, GO:0005730=GO_REF:0000052, GO:0016049=PMID:10925205, GO:0005634=GO_REF:0000052, GO:0005732=PMID:17636026, GO:0006608=PMID:10679015} Q9Y2X3 Nucleolar protein 58 protein 20101115 {GO:0005515=IPI, GO:0005737=IDA, GO:0015030=IDA, GO:0030515=IDA, GO:0031428=NAS, GO:0006364=TAS, GO:0070761=IDA, GO:0005730=IDA, GO:0016049=TAS, GO:0005634=IDA, GO:0005732=IDA, GO:0006608=ISS} cell growth, rRNA processing, snRNP protein import into nucleus Cajal body, box C/D snoRNP complex, cytoplasm, nucleolus, nucleus, pre-snoRNP complex, small nucleolar ribonucleoprotein complex protein binding, snoRNA binding Human NOS1 BHF-UCL UniProtKB {GO:0050661=GO_REF:0000024, GO:0005515=PMID:11149895, GO:0005516=GO_REF:0000037, GO:0048471=PMID:17027776, GO:0009408=PMID:18048451, GO:0007263=GO_REF:0000033, GO:0010523=PMID:17568574, GO:0010181=GO_REF:0000024, GO:0050660=GO_REF:0000024, GO:0045776=GO_REF:0000033, GO:0046870=GO_REF:0000024, GO:0005829=Reactome:REACT_23872, GO:0006809=PMID:7545544, GO:0005737=PMID:17892502, GO:0043197=GO_REF:0000039, GO:0045909=PMID:18048451, GO:0006527=PMID:7545544, GO:0005856=PMID:7545544, GO:0090382=Reactome:REACT_121256, GO:0001666=PMID:16276418, GO:0005506=GO_REF:0000002, GO:0051701=Reactome:REACT_121237, GO:0007520=PMID:7545544, GO:0033555=PMID:18391107, GO:0042383=PMID:7545544, GO:0001917=PMID:17027776, GO:0004517=PMID:7545544, GO:0016529=PMID:9892689, GO:0003958=GO_REF:0000033, GO:0034618=PMID:17029414, GO:0007596=Reactome:REACT_604, GO:0034617=PMID:7488039, GO:0055117=PMID:9892689, GO:0016491=GO_REF:0000033, GO:0031284=GO_REF:0000033, GO:0042136=PMID:7545544, GO:0020037=GO_REF:0000024} P29475 Nitric oxide synthase, brain protein 20080801 {GO:0050661=ISS, GO:0005515=IPI, GO:0005516=IEA, GO:0048471=ISS, GO:0009408=IDA, GO:0007263=IBA, GO:0010523=TAS, GO:0010181=ISS, GO:0050660=ISS, GO:0045776=IBA, GO:0046870=ISS, GO:0005829=TAS, GO:0006809=ISS, GO:0005737=TAS, GO:0043197=IEA, GO:0045909=IDA, GO:0006527=IC, GO:0005856=ISS, GO:0090382=TAS, GO:0001666=IEP, GO:0005506=IEA, GO:0051701=TAS, GO:0007520=TAS, GO:0033555=IMP, GO:0042383=IDA, GO:0001917=ISS, GO:0004517=ISS, GO:0016529=IDA, GO:0003958=IBA, GO:0034618=TAS, GO:0007596=TAS, GO:0034617=NAS, GO:0055117=TAS, GO:0016491=IBA, GO:0031284=IBA, GO:0042136=TAS, GO:0020037=ISS} arginine catabolic process, blood coagulation, interaction with host, multicellular organismal response to stress, myoblast fusion, negative regulation of blood pressure, negative regulation of calcium ion transport into cytosol, neurotransmitter biosynthetic process, nitric oxide biosynthetic process, nitric oxide mediated signal transduction, phagosome maturation, positive regulation of guanylate cyclase activity, positive regulation of vasodilation, regulation of cardiac muscle contraction, response to heat, response to hypoxia cytoplasm, cytoskeleton, cytosol, dendritic spine, perinuclear region of cytoplasm, photoreceptor inner segment, sarcolemma, sarcoplasmic reticulum FMN binding, NADP binding, NADPH-hemoprotein reductase activity, arginine binding, cadmium ion binding, calmodulin binding, flavin adenine dinucleotide binding, heme binding, iron ion binding, nitric-oxide synthase activity, oxidoreductase activity, protein binding, tetrahydrobiopterin binding Human NOS1AP UniProtKB UniProtKB {GO:0050998=PMID:9459447, GO:0045428=PMID:20431962, GO:0050999=PMID:20431962, GO:0042981=PMID:20431962, GO:0030165=PMID:9459447} O75052 Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein protein 20050214 {GO:0050998=ISS, GO:0045428=NAS, GO:0050999=NAS, GO:0042981=NAS, GO:0030165=ISS} regulation of apoptotic process, regulation of nitric oxide biosynthetic process, regulation of nitric-oxide synthase activity PDZ domain binding, nitric-oxide synthase binding Human UniProtKB:O54960 NOS2 BHF-UCL UniProtKB {GO:0050661=PMID:7504305, GO:0005515=PMID:12855682, GO:0005516=GO_REF:0000037, GO:0048471=GO_REF:0000019, GO:0007263=GO_REF:0000033, GO:0051712=PMID:7544003, GO:0010181=GO_REF:0000024, GO:0050660=GO_REF:0000024, GO:0006801=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0045776=GO_REF:0000033, GO:0043457=PMID:10450191, GO:0042803=GO_REF:0000024, GO:0006809=PMID:7504305, GO:0005829=PMID:7504305, GO:0005622=PMID:7544003, GO:0009617=PMID:12085352, GO:0005737=PMID:9916929, GO:0006954=GO_REF:0000033, GO:0042127=GO_REF:0000019, GO:0045909=GO_REF:0000033, GO:0006527=PMID:7504305, GO:0090382=Reactome:REACT_121256, GO:0042742=PMID:9284131, GO:0005777=PMID:12085352, GO:0001666=GO_REF:0000019, GO:0051701=Reactome:REACT_121237, GO:0005506=GO_REF:0000002, GO:0042177=GO_REF:0000019, GO:0005102=PMID:20178365, GO:0018119=GO_REF:0000024, GO:0002227=PMID:18390757, GO:0004517=PMID:7504305, GO:0050829=PMID:18390757, GO:0071222=GO_REF:0000019, GO:0034618=GO_REF:0000024, GO:0050796=PMID:8383325, GO:0003958=GO_REF:0000033, GO:0071346=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0034617=GO_REF:0000024, GO:0001912=PMID:10450191, GO:0030863=GO_REF:0000019, GO:0031284=GO_REF:0000033, GO:0020037=GO_REF:0000024} P35228 Nitric oxide synthase, inducible protein 20080801 {GO:0050661=TAS, GO:0005515=IPI, GO:0005516=IEA, GO:0048471=IEA, GO:0007263=IBA, GO:0051712=IMP, GO:0010181=ISS, GO:0050660=ISS, GO:0006801=ISS, GO:0005634=ISS, GO:0045776=IBA, GO:0043457=TAS, GO:0042803=ISS, GO:0006809=IDA, GO:0005829=IMP, GO:0005622=IDA, GO:0009617=NAS, GO:0005737=IDA, GO:0006954=IBA, GO:0042127=IEA, GO:0045909=IBA, GO:0006527=IDA, GO:0090382=TAS, GO:0042742=IMP, GO:0005777=IDA, GO:0001666=IEA, GO:0051701=TAS, GO:0005506=IEA, GO:0042177=IEA, GO:0005102=IPI, GO:0018119=ISS, GO:0002227=NAS, GO:0004517=IDA, GO:0050829=NAS, GO:0071222=IEA, GO:0034618=ISS, GO:0050796=IMP, GO:0003958=IBA, GO:0071346=IEA, GO:0007596=TAS, GO:0034617=ISS, GO:0001912=TAS, GO:0030863=IEA, GO:0031284=IBA, GO:0020037=ISS} arginine catabolic process, blood coagulation, cellular response to interferon-gamma, cellular response to lipopolysaccharide, defense response to Gram-negative bacterium, defense response to bacterium, inflammatory response, innate immune response in mucosa, interaction with host, negative regulation of blood pressure, negative regulation of protein catabolic process, nitric oxide biosynthetic process, nitric oxide mediated signal transduction, peptidyl-cysteine S-nitrosylation, phagosome maturation, positive regulation of guanylate cyclase activity, positive regulation of killing of cells of other organism, positive regulation of leukocyte mediated cytotoxicity, positive regulation of vasodilation, regulation of cell proliferation, regulation of cellular respiration, regulation of insulin secretion, response to bacterium, response to hypoxia, superoxide metabolic process cortical cytoskeleton, cytoplasm, cytosol, intracellular, nucleus, perinuclear region of cytoplasm, peroxisome FMN binding, NADP binding, NADPH-hemoprotein reductase activity, arginine binding, calmodulin binding, flavin adenine dinucleotide binding, heme binding, iron ion binding, nitric-oxide synthase activity, protein binding, protein homodimerization activity, receptor binding, tetrahydrobiopterin binding Human UniProtKB:P29477 NOS3 BHF-UCL UniProtKB {GO:0005515=PMID:12852865, GO:0005516=GO_REF:0000037, GO:0009408=PMID:18048451, GO:0010181=PMID:7488039, GO:0034405=PMID:10376603, GO:0043267=GO_REF:0000019, GO:0006809=PMID:1378832, GO:0050880=GO_REF:0000024, GO:0051926=GO_REF:0000019, GO:0005856=GO_REF:0000039, GO:0031663=GO_REF:0000019, GO:0003100=PMID:8999856, GO:0005506=GO_REF:0000002, GO:0051701=Reactome:REACT_121237, GO:0051346=GO_REF:0000019, GO:0014806=GO_REF:0000024, GO:0001542=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0004517=PMID:1378832, GO:0003958=GO_REF:0000033, GO:0043542=PMID:8999856, GO:0002028=GO_REF:0000019, GO:0031284=PMID:17502619, GO:0007005=GO_REF:0000024, GO:0020037=PMID:7488039, GO:0010544=PMID:7504210, GO:0050661=PMID:7488039, GO:0008285=GO_REF:0000024, GO:0007263=GO_REF:0000033, GO:0005886=Reactome:REACT_111249, GO:0030324=GO_REF:0000019, GO:0050660=PMID:7488039, GO:0050999=Reactome:REACT_12541, GO:0005634=GO_REF:0000024, GO:0045776=GO_REF:0000033, GO:0044281=Reactome:REACT_111217, GO:0046870=PMID:7488039, GO:0005829=Reactome:REACT_23872, GO:0005737=PMID:9794441, GO:0045909=PMID:18048451, GO:0046209=Reactome:REACT_12508, GO:0006527=PMID:1378832, GO:0090382=Reactome:REACT_121256, GO:0043066=GO_REF:0000024, GO:0001525=GO_REF:0000019, GO:0045766=GO_REF:0000024, GO:0030666=Reactome:REACT_12634, GO:0003785=PMID:17502619, GO:0014740=GO_REF:0000024, GO:0000139=Reactome:REACT_12590, GO:0034618=PMID:7488039, GO:0001974=GO_REF:0000024, GO:0007596=Reactome:REACT_604, GO:0005901=PMID:17848177, GO:0034617=PMID:7488039, GO:0003057=GO_REF:0000019, GO:0008217=PMID:7504210} P29474 Nitric oxide synthase, endothelial protein 20080725 {GO:0005515=IPI, GO:0005516=IEA, GO:0009408=NAS, GO:0010181=NAS, GO:0034405=IEP, GO:0043267=IEA, GO:0006809=IDA, GO:0050880=ISS, GO:0051926=IEA, GO:0005856=IEA, GO:0031663=IEA, GO:0003100=IMP, GO:0005506=IEA, GO:0051701=TAS, GO:0051346=IEA, GO:0014806=ISS, GO:0001542=IEA, GO:0001701=IEA, GO:0004517=IDA, GO:0003958=IBA, GO:0043542=IMP, GO:0002028=IEA, GO:0031284=IMP, GO:0007005=ISS, GO:0020037=IDA, GO:0010544=NAS, GO:0050661=NAS, GO:0008285=ISS, GO:0007263=IBA, GO:0005886=TAS, GO:0030324=IEA, GO:0050660=NAS, GO:0050999=TAS, GO:0005634=ISS, GO:0045776=IBA, GO:0044281=TAS, GO:0046870=NAS, GO:0005829=TAS, GO:0005737=IDA, GO:0045909=NAS, GO:0046209=TAS, GO:0006527=IDA, GO:0090382=TAS, GO:0043066=ISS, GO:0001525=IEA, GO:0045766=ISS, GO:0030666=TAS, GO:0003785=IPI, GO:0014740=ISS, GO:0000139=TAS, GO:0034618=IDA, GO:0001974=ISS, GO:0007596=TAS, GO:0005901=IDA, GO:0034617=IDA, GO:0003057=IEA, GO:0008217=NAS} angiogenesis, arginine catabolic process, blood coagulation, blood vessel remodeling, endothelial cell migration, in utero embryonic development, interaction with host, lipopolysaccharide-mediated signaling pathway, lung development, mitochondrion organization, negative regulation of apoptotic process, negative regulation of blood pressure, negative regulation of calcium ion transport, negative regulation of cell proliferation, negative regulation of hydrolase activity, negative regulation of muscle hyperplasia, negative regulation of platelet activation, negative regulation of potassium ion transport, nitric oxide biosynthetic process, nitric oxide mediated signal transduction, nitric oxide metabolic process, ovulation from ovarian follicle, phagosome maturation, positive regulation of angiogenesis, positive regulation of guanylate cyclase activity, positive regulation of vasodilation, regulation of blood pressure, regulation of blood vessel size, regulation of nitric-oxide synthase activity, regulation of sodium ion transport, regulation of systemic arterial blood pressure by endothelin, regulation of the force of heart contraction by chemical signal, response to fluid shear stress, response to heat, small molecule metabolic process, smooth muscle hyperplasia Golgi membrane, caveola, cytoplasm, cytoskeleton, cytosol, endocytic vesicle membrane, nucleus, plasma membrane FMN binding, NADP binding, NADPH-hemoprotein reductase activity, actin monomer binding, arginine binding, cadmium ion binding, calmodulin binding, flavin adenine dinucleotide binding, heme binding, iron ion binding, nitric-oxide synthase activity, protein binding, tetrahydrobiopterin binding Human NOSIP HPA UniProtKB {GO:0005515=PMID:11149895, GO:0005737=PMID:15548660, GO:0000139=Reactome:REACT_12590, GO:0051001=PMID:11149895, GO:0050999=Reactome:REACT_12510, GO:0046209=Reactome:REACT_12508, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0043086=PMID:11149895, GO:0005829=Reactome:REACT_12590} Q9Y314 Nitric oxide synthase-interacting protein protein 20110516 {GO:0005515=IPI, GO:0005737=IDA, GO:0000139=TAS, GO:0051001=IDA, GO:0050999=TAS, GO:0046209=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0043086=IDA, GO:0005829=TAS} negative regulation of catalytic activity, negative regulation of nitric-oxide synthase activity, nitric oxide metabolic process, regulation of nitric-oxide synthase activity, small molecule metabolic process Golgi membrane, cytoplasm, cytosol, nucleus protein binding Human NOSTRIN Reactome UniProtKB {GO:0030666=Reactome:REACT_12634, GO:0005886=Reactome:REACT_12634, GO:0050999=Reactome:REACT_12541, GO:0046209=Reactome:REACT_12508, GO:0044281=Reactome:REACT_111217, GO:0005856=GO_REF:0000039, GO:0006897=GO_REF:0000037} Q8IVI9 Nostrin protein 20130213 {GO:0030666=TAS, GO:0005886=TAS, GO:0050999=TAS, GO:0046209=TAS, GO:0044281=TAS, GO:0005856=IEA, GO:0006897=IEA} endocytosis, nitric oxide metabolic process, regulation of nitric-oxide synthase activity, small molecule metabolic process cytoskeleton, endocytic vesicle membrane, plasma membrane Human NOTCH1 BHF-UCL UniProtKB {GO:0060045=GO_REF:0000024, GO:0005515=PMID:19151708, GO:0001190=GO_REF:0000024, GO:0003700=GO_REF:0000019, GO:0042640=GO_REF:0000019, GO:1901201=GO_REF:0000024, GO:0010832=GO_REF:0000024, GO:2000811=PMID:17984306, GO:0045662=PMID:10713164, GO:0031069=GO_REF:0000019, GO:0007507=PMID:21457232, GO:0014031=GO_REF:0000024, GO:0003241=GO_REF:0000024, GO:0001708=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0072044=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0001701=GO_REF:0000019, GO:0043086=GO_REF:0000024, GO:0060038=GO_REF:0000019, GO:0031490=GO_REF:0000019, GO:0001889=GO_REF:0000019, GO:0005789=Reactome:REACT_118745, GO:0010001=GO_REF:0000019, GO:0010718=PMID:17984306, GO:0005634=GO_REF:0000024, GO:0072017=GO_REF:0000019, GO:0070986=GO_REF:0000019, GO:0001837=GO_REF:0000024, GO:0005829=Reactome:REACT_160171, GO:0071372=PMID:20613903, GO:0060317=GO_REF:0000024, GO:0061314=PMID:16025100, GO:0006955=PMID:1831692, GO:0009912=GO_REF:0000019, GO:0006959=GO_REF:0000019, GO:0004872=GO_REF:0000002, GO:0060528=GO_REF:0000019, GO:0004857=GO_REF:0000024, GO:0097150=PMID:19682396, GO:0003198=GO_REF:0000024, GO:0060843=GO_REF:0000024, GO:0060740=GO_REF:0000019, GO:0061384=GO_REF:0000024, GO:0060842=GO_REF:0000024, GO:0003192=PMID:16025100, GO:0005576=Reactome:REACT_160310, GO:0060253=GO_REF:0000024, GO:0003344=GO_REF:0000024, GO:0002193=PMID:16510869, GO:2000974=GO_REF:0000024, GO:0045668=GO_REF:0000024, GO:0007492=GO_REF:0000019, GO:0060948=GO_REF:0000024, GO:0030216=GO_REF:0000019, GO:0007440=GO_REF:0000019, GO:0035116=GO_REF:0000019, GO:0021915=GO_REF:0000019, GO:0030900=GO_REF:0000019, GO:0016021=GO_REF:0000029, GO:0048754=GO_REF:0000019, GO:0032495=GO_REF:0000019, GO:0003256=GO_REF:0000024, GO:0046533=GO_REF:0000019, GO:0010467=Reactome:REACT_71, GO:0007386=GO_REF:0000019, GO:0006367=Reactome:REACT_14835, GO:0007220=Reactome:REACT_2001, GO:0003180=PMID:17662764, GO:0003181=GO_REF:0000024, GO:0003184=PMID:16025100, GO:0007409=GO_REF:0000019, GO:0007221=GO_REF:0000024, GO:0001947=GO_REF:0000024, GO:0045618=GO_REF:0000019, GO:0007219=Reactome:REACT_118859, GO:0060956=GO_REF:0000024, GO:0055008=GO_REF:0000024, GO:0050679=GO_REF:0000019, GO:0030335=GO_REF:0000024, GO:0003273=GO_REF:0000024, GO:0003270=GO_REF:0000019, GO:0001047=GO_REF:0000024, GO:0014807=GO_REF:0000019, GO:0000122=GO_REF:0000024, GO:0060768=GO_REF:0000019, GO:0005654=Reactome:REACT_160309, GO:0072602=GO_REF:0000019, GO:0045893=GO_REF:0000024, GO:0019899=GO_REF:0000024, GO:0072144=GO_REF:0000019, GO:0045892=GO_REF:0000024, GO:0002437=GO_REF:0000019, GO:0048103=GO_REF:0000019, GO:0003160=GO_REF:0000024, GO:0007368=GO_REF:0000024, GO:0008284=PMID:20613903, GO:0005886=Reactome:REACT_160310, GO:0030324=GO_REF:0000019, GO:0061419=GO_REF:0000024, GO:0010812=PMID:16501043, GO:0002040=GO_REF:0000019, GO:0003214=GO_REF:0000024, GO:0003169=GO_REF:0000024, GO:0003162=GO_REF:0000019, GO:0003219=GO_REF:0000019, GO:2000737=PMID:19682396, GO:0030514=GO_REF:0000024, GO:0030513=GO_REF:0000024, GO:0060979=GO_REF:0000024, GO:0030279=GO_REF:0000024, GO:0050768=GO_REF:0000024, GO:0045944=GO_REF:0000024, GO:0003222=GO_REF:0000024, GO:0090090=GO_REF:0000019, GO:0006355=PMID:10713164, GO:0043065=GO_REF:0000019, GO:0060412=PMID:16025100, GO:0060411=GO_REF:0000024, GO:0003157=GO_REF:0000024, GO:0003203=GO_REF:0000024, GO:0003208=GO_REF:0000024, GO:0003207=GO_REF:0000024, GO:0003209=GO_REF:0000024, GO:0046427=GO_REF:0000024, GO:0043565=GO_REF:0000019, GO:0048711=GO_REF:0000024, GO:0045955=GO_REF:0000019, GO:0000139=Reactome:REACT_118833, GO:0003213=GO_REF:0000024, GO:0048715=GO_REF:0000024, GO:0060982=GO_REF:0000024} P46531 Neurogenic locus notch homolog protein 1 protein 20120806 {GO:0060045=ISS, GO:0005515=IPI, GO:0001190=ISS, GO:0003700=IEA, GO:0042640=IEA, GO:1901201=ISS, GO:0010832=ISS, GO:2000811=IMP, GO:0045662=IMP, GO:0031069=IEA, GO:0007507=IMP, GO:0014031=ISS, GO:0003241=ISS, GO:0001708=IEA, GO:0009986=IEA, GO:0072044=IEA, GO:0005509=IEA, GO:0001701=IEA, GO:0043086=ISS, GO:0060038=IEA, GO:0031490=IEA, GO:0001889=IEA, GO:0005789=TAS, GO:0010001=IEA, GO:0010718=IMP, GO:0005634=ISS, GO:0072017=IEA, GO:0070986=IEA, GO:0001837=ISS, GO:0005829=TAS, GO:0071372=IDA, GO:0060317=ISS, GO:0061314=IMP, GO:0006955=NAS, GO:0009912=IEA, GO:0006959=IEA, GO:0004872=IEA, GO:0060528=IEA, GO:0004857=ISS, GO:0097150=IEP, GO:0003198=ISS, GO:0060843=ISS, GO:0060740=IEA, GO:0061384=ISS, GO:0060842=ISS, GO:0003192=IMP, GO:0005576=TAS, GO:0060253=ISS, GO:0003344=ISS, GO:0002193=IDA, GO:2000974=ISS, GO:0045668=ISS, GO:0007492=IEA, GO:0060948=ISS, GO:0030216=IEA, GO:0007440=IEA, GO:0035116=IEA, GO:0021915=IEA, GO:0030900=IEA, GO:0016021=NAS, GO:0048754=IEA, GO:0032495=IEA, GO:0003256=ISS, GO:0046533=IEA, GO:0010467=TAS, GO:0007386=IEA, GO:0006367=TAS, GO:0007220=TAS, GO:0003180=IMP, GO:0003181=ISS, GO:0003184=IMP, GO:0007409=IEA, GO:0007221=ISS, GO:0001947=ISS, GO:0045618=IEA, GO:0007219=TAS, GO:0060956=ISS, GO:0055008=ISS, GO:0050679=IEA, GO:0030335=ISS, GO:0003273=ISS, GO:0003270=IEA, GO:0001047=ISS, GO:0014807=IEA, GO:0000122=ISS, GO:0060768=IEA, GO:0005654=TAS, GO:0072602=IEA, GO:0045893=ISS, GO:0019899=ISS, GO:0072144=IEA, GO:0045892=ISS, GO:0002437=IEA, GO:0048103=IEA, GO:0003160=ISS, GO:0007368=ISS, GO:0008284=IMP, GO:0005886=TAS, GO:0030324=IEA, GO:0061419=ISS, GO:0010812=IDA, GO:0002040=IEA, GO:0003214=ISS, GO:0003169=ISS, GO:0003162=IEA, GO:0003219=IEA, GO:2000737=IMP, GO:0030514=ISS, GO:0030513=ISS, GO:0060979=ISS, GO:0030279=ISS, GO:0050768=ISS, GO:0045944=ISS, GO:0003222=ISS, GO:0090090=IEA, GO:0006355=TAS, GO:0043065=IEA, GO:0060412=IMP, GO:0060411=ISS, GO:0003157=ISS, GO:0003203=ISS, GO:0003208=ISS, GO:0003207=ISS, GO:0003209=ISS, GO:0046427=ISS, GO:0043565=IEA, GO:0048711=ISS, GO:0045955=IEA, GO:0000139=TAS, GO:0003213=ISS, GO:0048715=ISS, GO:0060982=ISS} Notch receptor processing, Notch signaling involved in heart development, Notch signaling pathway, Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation, anagen, aortic valve morphogenesis, arterial endothelial cell differentiation, atrioventricular node development, atrioventricular valve morphogenesis, auditory receptor cell fate commitment, axonogenesis, branching morphogenesis of an epithelial tube, cardiac atrium morphogenesis, cardiac chamber formation, cardiac epithelial to mesenchymal transition, cardiac left ventricle morphogenesis, cardiac muscle cell proliferation, cardiac muscle tissue morphogenesis, cardiac right atrium morphogenesis, cardiac right ventricle formation, cardiac septum morphogenesis, cardiac vascular smooth muscle cell development, cardiac ventricle morphogenesis, cell fate specification, cell migration involved in endocardial cushion formation, cellular response to follicle-stimulating hormone stimulus, collecting duct development, compartment pattern specification, coronary artery morphogenesis, coronary vein morphogenesis, determination of left/right symmetry, distal tubule development, embryonic hindlimb morphogenesis, endocardial cell differentiation, endocardial cushion morphogenesis, endocardium development, endocardium morphogenesis, endoderm development, epithelial to mesenchymal transition, epithelial to mesenchymal transition involved in endocardial cushion formation, forebrain development, foregut morphogenesis, gene expression, glial cell differentiation, glomerular mesangial cell development, growth involved in heart morphogenesis, hair follicle morphogenesis, heart development, heart looping, heart trabecula morphogenesis, humoral immune response, immune response, in utero embryonic development, inflammatory response to antigenic stimulus, interleukin-4 secretion, keratinocyte differentiation, left/right axis specification, liver development, lung development, mesenchymal cell development, mitral valve formation, negative regulation of BMP signaling pathway, negative regulation of anoikis, negative regulation of calcium ion-dependent exocytosis, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of catalytic activity, negative regulation of cell-substrate adhesion, negative regulation of glial cell proliferation, negative regulation of myoblast differentiation, negative regulation of myotube differentiation, negative regulation of neurogenesis, negative regulation of oligodendrocyte differentiation, negative regulation of ossification, negative regulation of osteoblast differentiation, negative regulation of photoreceptor cell differentiation, negative regulation of pro-B cell differentiation, negative regulation of stem cell differentiation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, neural tube development, neuronal stem cell maintenance, pericardium morphogenesis, positive regulation of BMP signaling pathway, positive regulation of JAK-STAT cascade, positive regulation of apoptotic process, positive regulation of astrocyte differentiation, positive regulation of cardiac muscle cell proliferation, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of epithelial cell proliferation, positive regulation of epithelial to mesenchymal transition, positive regulation of keratinocyte differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter in response to hypoxia, positive regulation of transcription of Notch receptor target, positive regulation of transcription, DNA-dependent, prostate gland epithelium morphogenesis, pulmonary valve morphogenesis, regulation of epithelial cell proliferation involved in prostate gland development, regulation of extracellular matrix assembly, regulation of somitogenesis, regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation, regulation of transcription, DNA-dependent, response to muramyl dipeptide, secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development, somatic stem cell division, sprouting angiogenesis, transcription initiation from RNA polymerase II promoter, vasculogenesis involved in coronary vascular morphogenesis, venous endothelial cell differentiation, ventricular septum morphogenesis, ventricular trabecula myocardium morphogenesis Golgi membrane, MAML1-RBP-Jkappa- ICN1 complex, cell surface, cytosol, endoplasmic reticulum membrane, extracellular region, integral to membrane, nucleoplasm, nucleus, plasma membrane RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription, calcium ion binding, chromatin DNA binding, core promoter binding, enzyme binding, enzyme inhibitor activity, protein binding, receptor activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human NOTCH2 BHF-UCL UniProtKB {GO:0005515=PMID:11101851, GO:0002437=GO_REF:0000019, GO:0010467=Reactome:REACT_71, GO:0007368=GO_REF:0000019, GO:0007220=Reactome:REACT_2001, GO:0006367=Reactome:REACT_14835, GO:0060674=GO_REF:0000019, GO:0008285=PMID:11306509, GO:0005886=Reactome:REACT_160320, GO:0003184=PMID:16773578, GO:0005634=PMID:1303260, GO:0046579=PMID:11306509, GO:0030326=GO_REF:0000019, GO:0061314=PMID:16773578, GO:0007219=Reactome:REACT_118721, GO:0046849=PMID:21378985, GO:0006959=GO_REF:0000019, GO:0009887=PMID:12531696, GO:0004872=PMID:9244302, GO:0007050=PMID:11306509, GO:0030097=PMID:1303260, GO:0006355=PMID:9244302, GO:0043066=PMID:12531696, GO:0009986=PMID:9244302, GO:0002011=GO_REF:0000019, GO:0001709=PMID:9244302, GO:0060413=PMID:16773578, GO:0005509=GO_REF:0000002, GO:0005576=Reactome:REACT_160320, GO:0007275=PMID:9244302, GO:0006917=PMID:12531696, GO:0001701=GO_REF:0000019, GO:0007399=PMID:12760378, GO:0000139=Reactome:REACT_118833, GO:0005887=PMID:9244302, GO:0019827=PMID:11306509, GO:0005789=Reactome:REACT_118612, GO:0016049=PMID:11306509, GO:0005654=Reactome:REACT_14814, GO:0072602=GO_REF:0000019} Q04721 Neurogenic locus notch homolog protein 2 protein 20120806 {GO:0005515=IPI, GO:0002437=IEA, GO:0010467=TAS, GO:0007368=IEA, GO:0007220=TAS, GO:0006367=TAS, GO:0060674=IEA, GO:0008285=IDA, GO:0005886=TAS, GO:0003184=IMP, GO:0005634=IDA, GO:0046579=IDA, GO:0030326=IEA, GO:0061314=IC, GO:0007219=TAS, GO:0046849=IMP, GO:0006959=IEA, GO:0009887=IEP, GO:0004872=NAS, GO:0007050=IDA, GO:0030097=TAS, GO:0006355=TAS, GO:0043066=TAS, GO:0009986=IDA, GO:0002011=IEA, GO:0001709=TAS, GO:0060413=IMP, GO:0005509=IEA, GO:0005576=TAS, GO:0007275=NAS, GO:0006917=TAS, GO:0001701=IEA, GO:0007399=NAS, GO:0000139=TAS, GO:0005887=IDA, GO:0019827=TAS, GO:0005789=TAS, GO:0016049=IDA, GO:0005654=TAS, GO:0072602=IEA} Notch receptor processing, Notch signaling involved in heart development, Notch signaling pathway, atrial septum morphogenesis, bone remodeling, cell cycle arrest, cell fate determination, cell growth, determination of left/right symmetry, embryonic limb morphogenesis, gene expression, hemopoiesis, humoral immune response, in utero embryonic development, induction of apoptosis, inflammatory response to antigenic stimulus, interleukin-4 secretion, morphogenesis of an epithelial sheet, multicellular organismal development, negative regulation of apoptotic process, negative regulation of cell proliferation, nervous system development, organ morphogenesis, placenta blood vessel development, positive regulation of Ras protein signal transduction, pulmonary valve morphogenesis, regulation of transcription, DNA-dependent, stem cell maintenance, transcription initiation from RNA polymerase II promoter Golgi membrane, cell surface, endoplasmic reticulum membrane, extracellular region, integral to plasma membrane, nucleoplasm, nucleus, plasma membrane calcium ion binding, protein binding, receptor activity Human NOTCH2NL UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0007219=GO_REF:0000037, GO:0005509=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q7Z3S9 Notch homolog 2 N-terminal-like protein protein 20130413 {GO:0005737=IEA, GO:0007219=IEA, GO:0005509=IEA, GO:0005576=IEA, GO:0007275=IEA, GO:0030154=IEA} Notch signaling pathway, cell differentiation, multicellular organismal development cytoplasm, extracellular region calcium ion binding Human UniProtKB-SubCell:SL-0086 NOTCH3 IntAct UniProtKB {GO:0005515=PMID:17292860, GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000037, GO:0007220=Reactome:REACT_2001, GO:0006367=Reactome:REACT_14835, GO:0005886=Reactome:REACT_118747, GO:0005509=GO_REF:0000002, GO:0005576=Reactome:REACT_118747, GO:0072104=GO_REF:0000019, GO:0048663=GO_REF:0000019, GO:0048661=GO_REF:0000019, GO:0005829=Reactome:REACT_1803, GO:0045665=GO_REF:0000019, GO:0000139=Reactome:REACT_118833, GO:0007219=Reactome:REACT_118862, GO:0005789=Reactome:REACT_118714, GO:0005654=Reactome:REACT_14814, GO:0016021=GO_REF:0000037, GO:0030900=GO_REF:0000019, GO:0019899=GO_REF:0000019} Q9UM47 Neurogenic locus notch homolog protein 3 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0006355=IEA, GO:0007220=TAS, GO:0006367=TAS, GO:0005886=TAS, GO:0005509=IEA, GO:0005576=TAS, GO:0072104=IEA, GO:0048663=IEA, GO:0048661=IEA, GO:0005829=TAS, GO:0045665=IEA, GO:0000139=TAS, GO:0007219=TAS, GO:0005789=TAS, GO:0005654=TAS, GO:0016021=IEA, GO:0030900=IEA, GO:0019899=IEA} Notch receptor processing, Notch signaling pathway, forebrain development, gene expression, glomerular capillary formation, negative regulation of neuron differentiation, neuron fate commitment, positive regulation of smooth muscle cell proliferation, regulation of transcription, DNA-dependent, transcription initiation from RNA polymerase II promoter Golgi membrane, cytosol, endoplasmic reticulum membrane, extracellular region, integral to membrane, nucleoplasm, plasma membrane calcium ion binding, enzyme binding, protein binding Human UniProtKB:Q9R1P4 NOTCH4 BHF-UCL UniProtKB {GO:0005515=PMID:11101851, GO:0010467=Reactome:REACT_71, GO:0007220=Reactome:REACT_2001, GO:0006367=Reactome:REACT_14835, GO:0005886=Reactome:REACT_118747, GO:0005634=PMID:8681805, GO:0030879=PMID:9576833, GO:0009790=GO_REF:0000024, GO:0007221=PMID:18663143, GO:0030154=PMID:11823422, GO:0005829=Reactome:REACT_965, GO:0007219=Reactome:REACT_118636, GO:0004872=PMID:11823422, GO:0030097=PMID:11532344, GO:0001569=GO_REF:0000024, GO:0009986=PMID:11823422, GO:0046982=PMID:8681805, GO:0001709=PMID:11823422, GO:0005509=PMID:11823422, GO:0007275=GO_REF:0000002, GO:0005576=Reactome:REACT_118747, GO:0000139=Reactome:REACT_118833, GO:0001886=GO_REF:0000019, GO:0005887=PMID:11823422, GO:0050793=GO_REF:0000002, GO:0005789=Reactome:REACT_118578, GO:0005654=Reactome:REACT_14814, GO:0045596=PMID:11823422, GO:0016021=GO_REF:0000002, GO:0045893=PMID:11823422, GO:0045602=GO_REF:0000024, GO:0001763=GO_REF:0000024} Q99466 Neurogenic locus notch homolog protein 4 protein 20120727 {GO:0005515=IPI, GO:0010467=TAS, GO:0007220=TAS, GO:0006367=TAS, GO:0005886=TAS, GO:0005634=TAS, GO:0030879=IDA, GO:0009790=ISS, GO:0007221=TAS, GO:0030154=NAS, GO:0005829=TAS, GO:0007219=TAS, GO:0004872=TAS, GO:0030097=TAS, GO:0001569=ISS, GO:0009986=IDA, GO:0046982=TAS, GO:0001709=TAS, GO:0005509=TAS, GO:0007275=IEA, GO:0005576=TAS, GO:0000139=TAS, GO:0001886=IEA, GO:0005887=TAS, GO:0050793=IEA, GO:0005789=TAS, GO:0005654=TAS, GO:0045596=NAS, GO:0016021=IEA, GO:0045893=TAS, GO:0045602=ISS, GO:0001763=ISS} Notch receptor processing, Notch signaling pathway, cell differentiation, cell fate determination, embryo development, endothelial cell morphogenesis, gene expression, hemopoiesis, mammary gland development, morphogenesis of a branching structure, multicellular organismal development, negative regulation of cell differentiation, negative regulation of endothelial cell differentiation, patterning of blood vessels, positive regulation of transcription of Notch receptor target, positive regulation of transcription, DNA-dependent, regulation of developmental process, transcription initiation from RNA polymerase II promoter Golgi membrane, cell surface, cytosol, endoplasmic reticulum membrane, extracellular region, integral to membrane, integral to plasma membrane, nucleoplasm, nucleus, plasma membrane calcium ion binding, protein binding, protein heterodimerization activity, receptor activity Human NOV HPA UniProtKB {GO:0031012=GO_REF:0000019, GO:0010468=GO_REF:0000019, GO:0030424=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0008083=GO_REF:0000037, GO:0001558=GO_REF:0000002, GO:0030425=GO_REF:0000019, GO:0043231=GO_REF:0000052, GO:0005520=GO_REF:0000002} P48745 Protein NOV homolog protein 20100326 {GO:0031012=IEA, GO:0010468=IEA, GO:0030424=IEA, GO:0043025=IEA, GO:0005576=IEA, GO:0008083=IEA, GO:0001558=IEA, GO:0030425=IEA, GO:0043231=IDA, GO:0005520=IEA} regulation of cell growth, regulation of gene expression axon, dendrite, extracellular matrix, extracellular region, intracellular membrane-bounded organelle, neuronal cell body growth factor activity, insulin-like growth factor binding Human NOVA1 PINC UniProtKB {GO:0008380=PMID:8398153, GO:0006396=PMID:8398153, GO:0000398=GO_REF:0000019, GO:0003723=PMID:8558240, GO:0007268=PMID:8558240, GO:0007626=PMID:8558240, GO:0005634=GO_REF:0000039, GO:0003729=GO_REF:0000019} P51513 RNA-binding protein Nova-1 protein 20030904 {GO:0008380=TAS, GO:0006396=TAS, GO:0000398=IEA, GO:0003723=TAS, GO:0007268=TAS, GO:0007626=TAS, GO:0005634=IEA, GO:0003729=IEA} RNA processing, RNA splicing, locomotory behavior, mRNA splicing, via spliceosome, synaptic transmission nucleus RNA binding, mRNA binding Human NOX1 BHF-UCL UniProtKB {GO:0050661=PMID:10485709, GO:0005515=PMID:16636067, GO:0045730=PMID:16636067, GO:0008284=PMID:10485709, GO:0030054=GO_REF:0000037, GO:0006801=PMID:18023288, GO:0006746=GO_REF:0000029, GO:0046872=GO_REF:0000037, GO:0003081=GO_REF:0000019, GO:0006954=PMID:18347018, GO:0016175=PMID:10485709, GO:0030198=GO_REF:0000019, GO:0071438=PMID:19755710, GO:0042743=PMID:11331784, GO:0009268=PMID:10615049, GO:0042554=PMID:10485709, GO:0072592=GO_REF:0000019, GO:0006950=PMID:10615049, GO:0006739=PMID:10485709, GO:0001525=PMID:11805326, GO:0045726=PMID:18023288, GO:0048661=PMID:10485709, GO:0010575=PMID:11805326, GO:0030171=PMID:10615049, GO:0007165=PMID:17673675, GO:0048365=PMID:16636067, GO:0016020=GO_REF:0000002, GO:0016477=PMID:18023288, GO:0008217=PMID:18347018, GO:0016491=GO_REF:0000002, GO:0051454=PMID:10615049, GO:0043020=PMID:16636067, GO:0016021=PMID:10615049, GO:0022900=GO_REF:0000037, GO:0005769=PMID:17673675, GO:0015992=PMID:10615049, GO:0055114=PMID:10615049} Q9Y5S8 NADPH oxidase 1 protein 20080618 {GO:0050661=IC, GO:0005515=IPI, GO:0045730=TAS, GO:0008284=IDA, GO:0030054=IEA, GO:0006801=IMP, GO:0006746=NAS, GO:0046872=IEA, GO:0003081=IEA, GO:0006954=TAS, GO:0016175=IC, GO:0030198=IEA, GO:0071438=IDA, GO:0042743=IDA, GO:0009268=IDA, GO:0042554=IDA, GO:0072592=IEA, GO:0006950=IDA, GO:0006739=IC, GO:0001525=IMP, GO:0045726=IMP, GO:0048661=ISS, GO:0010575=IEP, GO:0030171=IDA, GO:0007165=TAS, GO:0048365=IPI, GO:0016020=IEA, GO:0016477=IMP, GO:0008217=TAS, GO:0016491=IEA, GO:0051454=IDA, GO:0043020=IDA, GO:0016021=IC, GO:0022900=IEA, GO:0005769=IDA, GO:0015992=IDA, GO:0055114=IDA} FADH2 metabolic process, NADP metabolic process, angiogenesis, cell migration, electron transport chain, extracellular matrix organization, hydrogen peroxide metabolic process, inflammatory response, intracellular pH elevation, oxidation-reduction process, oxygen metabolic process, positive regulation of cell proliferation, positive regulation of integrin biosynthetic process, positive regulation of smooth muscle cell proliferation, positive regulation vascular endothelial growth factor production, proton transport, regulation of blood pressure, regulation of systemic arterial blood pressure by renin-angiotensin, respiratory burst, response to pH, response to stress, signal transduction, superoxide anion generation, superoxide metabolic process NADPH oxidase complex, cell junction, early endosome, integral to membrane, invadopodium membrane, membrane NADP binding, Rac GTPase binding, metal ion binding, oxidoreductase activity, protein binding, superoxide-generating NADPH oxidase activity, voltage-gated proton channel activity Human UniProtKB:Q9WV87 NOX4 UniProtKB UniProtKB {GO:0051897=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0008285=PMID:10869423, GO:2000573=GO_REF:0000019, GO:0045453=GO_REF:0000019, GO:0050660=PMID:10869423, GO:0071560=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0071480=GO_REF:0000019, GO:0050667=PMID:20031578, GO:0014911=GO_REF:0000019, GO:0072341=PMID:20031578, GO:0005739=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0006954=PMID:10869423, GO:0000166=PMID:10869423, GO:0016175=GO_REF:0000019, GO:0043406=GO_REF:0000019, GO:0016174=PMID:10869423, GO:0070374=GO_REF:0000019, GO:0071333=GO_REF:0000019, GO:0042554=PMID:10869423, GO:0001666=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0007569=PMID:10869423, GO:0072593=PMID:10869423, GO:0009055=PMID:10869423, GO:0035051=GO_REF:0000019, GO:0000902=PMID:10869423, GO:0019826=PMID:10869423, GO:0051496=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0016491=GO_REF:0000038, GO:0016021=PMID:10869423, GO:0043020=GO_REF:0000019, GO:0071320=GO_REF:0000019, GO:2000379=GO_REF:0000019, GO:0005925=GO_REF:0000039, GO:0020037=PMID:10869423, GO:0055114=PMID:10869423} Q9NPH5 NADPH oxidase 4 protein 20111223 {GO:0051897=IEA, GO:0048471=IEA, GO:0008285=ISS, GO:2000573=IEA, GO:0045453=IEA, GO:0050660=TAS, GO:0071560=IEA, GO:0005634=IEA, GO:0071480=IEA, GO:0050667=IDA, GO:0014911=IEA, GO:0072341=IDA, GO:0005739=IEA, GO:0016324=IEA, GO:0006954=TAS, GO:0000166=TAS, GO:0016175=IEA, GO:0043406=IEA, GO:0016174=TAS, GO:0070374=IEA, GO:0071333=IEA, GO:0042554=ISS, GO:0001666=IEA, GO:0043065=IEA, GO:0007569=ISS, GO:0072593=IDA, GO:0009055=TAS, GO:0035051=IEA, GO:0000902=ISS, GO:0019826=TAS, GO:0051496=IEA, GO:0005789=IEA, GO:0016491=IEA, GO:0016021=TAS, GO:0043020=IEA, GO:0071320=IEA, GO:2000379=IEA, GO:0005925=IEA, GO:0020037=TAS, GO:0055114=IDA} bone resorption, cardiocyte differentiation, cell aging, cell morphogenesis, cellular response to cAMP, cellular response to gamma radiation, cellular response to glucose stimulus, cellular response to transforming growth factor beta stimulus, homocysteine metabolic process, inflammatory response, negative regulation of cell proliferation, oxidation-reduction process, positive regulation of DNA biosynthetic process, positive regulation of ERK1 and ERK2 cascade, positive regulation of MAP kinase activity, positive regulation of apoptotic process, positive regulation of protein kinase B signaling cascade, positive regulation of reactive oxygen species metabolic process, positive regulation of smooth muscle cell migration, positive regulation of stress fiber assembly, reactive oxygen species metabolic process, response to hypoxia, superoxide anion generation NADPH oxidase complex, apical plasma membrane, endoplasmic reticulum membrane, focal adhesion, integral to membrane, mitochondrion, nucleus, perinuclear region of cytoplasm NAD(P)H oxidase activity, electron carrier activity, flavin adenine dinucleotide binding, heme binding, modified amino acid binding, nucleotide binding, oxidoreductase activity, oxygen sensor activity, superoxide-generating NADPH oxidase activity Human NOX5 GOC UniProtKB {GO:0042554=PMID:11483596, GO:0050661=PMID:11483596, GO:0050663=PMID:11483596, GO:0005783=GO_REF:0000039, GO:0008283=PMID:11483596, GO:0043012=PMID:11483596, GO:0005509=GO_REF:0000002, GO:0050660=PMID:11483596, GO:0001525=GO_REF:0000037, GO:0006917=PMID:11483596, GO:0000910=PMID:11483596, GO:0016175=PMID:11483596, GO:0001935=PMID:17275676, GO:0015252=PMID:11483596, GO:0010155=PMID:11483596, GO:0016021=GO_REF:0000037, GO:0022900=GO_REF:0000037, GO:0015992=PMID:11483596, GO:0055114=PMID:11483596, GO:0020037=PMID:11483596} Q96PH1 NADPH oxidase 5 protein 20130413 {GO:0042554=IDA, GO:0050661=NAS, GO:0050663=NAS, GO:0005783=IEA, GO:0008283=NAS, GO:0043012=NAS, GO:0005509=IEA, GO:0050660=NAS, GO:0001525=IEA, GO:0006917=NAS, GO:0000910=NAS, GO:0016175=IDA, GO:0001935=IDA, GO:0015252=IDA, GO:0010155=NAS, GO:0016021=IEA, GO:0022900=IEA, GO:0015992=IDA, GO:0055114=IDA, GO:0020037=NAS} angiogenesis, cell proliferation, cytokine secretion, cytokinesis, electron transport chain, endothelial cell proliferation, induction of apoptosis, oxidation-reduction process, proton transport, regulation of fusion of sperm to egg plasma membrane, regulation of proton transport, superoxide anion generation endoplasmic reticulum, integral to membrane NADP binding, calcium ion binding, flavin adenine dinucleotide binding, heme binding, hydrogen ion channel activity, superoxide-generating NADPH oxidase activity Human NOXA1 BHF-UCL UniProtKB {GO:0005515=PMID:16636067, GO:0048365=PMID:16636067, GO:0017124=PMID:19755710, GO:0005737=GO_REF:0000039, GO:0016176=PMID:16636067, GO:0006801=PMID:20609497, GO:0060263=PMID:16636067, GO:0010310=PMID:16636067, GO:0043020=PMID:16636067, GO:0019899=PMID:16636067} Q86UR1 NADPH oxidase activator 1 protein 20080620 {GO:0005515=IPI, GO:0048365=IPI, GO:0017124=IPI, GO:0005737=IEA, GO:0016176=IMP, GO:0006801=IMP, GO:0060263=IMP, GO:0010310=IMP, GO:0043020=IDA, GO:0019899=IPI} regulation of hydrogen peroxide metabolic process, regulation of respiratory burst, superoxide metabolic process NADPH oxidase complex, cytoplasm Rac GTPase binding, SH3 domain binding, enzyme binding, protein binding, superoxide-generating NADPH oxidase activator activity Human UniProtKB:P63000 NOXO1 BHF-UCL UniProtKB {GO:0005515=PMID:16636067, GO:0005543=PMID:16636067, GO:0007154=GO_REF:0000002, GO:0016176=PMID:16636067, GO:0022617=PMID:19755710, GO:0006801=GO_REF:0000019, GO:0060263=PMID:16636067, GO:0010310=PMID:16636067, GO:0043020=PMID:16636067, GO:0019899=PMID:16636067, GO:0035091=GO_REF:0000002} Q8NFA2 NADPH oxidase organizer 1 protein 20080620 {GO:0005515=IPI, GO:0005543=TAS, GO:0007154=IEA, GO:0016176=TAS, GO:0022617=IMP, GO:0006801=IEA, GO:0060263=TAS, GO:0010310=TAS, GO:0043020=IDA, GO:0019899=IPI, GO:0035091=IEA} cell communication, extracellular matrix disassembly, regulation of hydrogen peroxide metabolic process, regulation of respiratory burst, superoxide metabolic process NADPH oxidase complex enzyme binding, phosphatidylinositol binding, phospholipid binding, protein binding, superoxide-generating NADPH oxidase activator activity Human NPAS1 PINC UniProtKB {GO:0003700=PMID:9012850, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0004871=GO_REF:0000002, GO:0007417=PMID:9012850, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q99742 Neuronal PAS domain-containing protein 1 protein 20030904 {GO:0003700=TAS, GO:0046983=IEA, GO:0005634=IEA, GO:0004871=IEA, GO:0007417=TAS, GO:0003677=IEA, GO:0006351=IEA} central nervous system development, transcription, DNA-dependent nucleus DNA binding, protein dimerization activity, sequence-specific DNA binding transcription factor activity, signal transducer activity Human NPAS2 BHF-UCL UniProtKB {GO:0005667=PMID:9576906, GO:0045475=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0051879=PMID:9079689, GO:0044281=Reactome:REACT_111217, GO:0007417=PMID:9012850, GO:0003677=PMID:9576906, GO:0006351=GO_REF:0000037, GO:0005829=Reactome:REACT_116112, GO:0005737=GO_REF:0000002, GO:0042745=GO_REF:0000019, GO:0045944=PMID:9576906, GO:0046983=GO_REF:0000002, GO:0004871=GO_REF:0000002, GO:0044255=Reactome:REACT_22279} Q99743 Neuronal PAS domain-containing protein 2 protein 20080522 {GO:0005667=IPI, GO:0045475=IEA, GO:0003700=IEA, GO:0051879=IDA, GO:0044281=TAS, GO:0007417=TAS, GO:0003677=IPI, GO:0006351=IEA, GO:0005829=TAS, GO:0005737=IEA, GO:0042745=IEA, GO:0045944=IGI, GO:0046983=IEA, GO:0004871=IEA, GO:0044255=TAS} cellular lipid metabolic process, central nervous system development, circadian sleep/wake cycle, locomotor rhythm, positive regulation of transcription from RNA polymerase II promoter, small molecule metabolic process, transcription, DNA-dependent cytoplasm, cytosol, transcription factor complex DNA binding, Hsp90 protein binding, protein dimerization activity, sequence-specific DNA binding transcription factor activity, signal transducer activity Human NPAS4 ENSEMBL UniProtKB {GO:0005667=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0004871=GO_REF:0000002, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q8IUM7 Neuronal PAS domain-containing protein 4 protein 20130413 {GO:0005667=IEA, GO:0046982=IEA, GO:0045944=IEA, GO:0046983=IEA, GO:0004871=IEA, GO:0003677=IEA, GO:0006351=IEA} positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent transcription factor complex DNA binding, protein dimerization activity, protein heterodimerization activity, signal transducer activity Human Ensembl:ENSRNOP00000027119 NPAT UniProtKB UniProtKB {GO:0010468=PMID:15988025, GO:0005515=PMID:18850719, GO:0003700=PMID:18850719, GO:0015030=PMID:17577209, GO:0003714=PMID:17163457, GO:0003713=PMID:15988025, GO:0005634=PMID:15988025, GO:0008022=PMID:15988025, GO:0006351=GO_REF:0000037, GO:0000083=PMID:15988025, GO:0047485=PMID:19170105, GO:0044428=PMID:19170105, GO:0045893=PMID:18850719} Q14207 Protein NPAT protein 20090723 {GO:0010468=IMP, GO:0005515=IPI, GO:0003700=IDA, GO:0015030=IDA, GO:0003714=IMP, GO:0003713=IMP, GO:0005634=IDA, GO:0008022=IPI, GO:0006351=IEA, GO:0000083=IMP, GO:0047485=IPI, GO:0044428=IDA, GO:0045893=IDA} positive regulation of transcription, DNA-dependent, regulation of gene expression, regulation of transcription involved in G1/S phase of mitotic cell cycle, transcription, DNA-dependent Cajal body, nuclear part, nucleus protein C-terminus binding, protein N-terminus binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, transcription corepressor activity Human NPB Reactome UniProtKB {GO:0005515=PMID:12401809, GO:0001664=GO_REF:0000019, GO:0007186=PMID:12118011, GO:0007218=GO_REF:0000037, GO:0005576=Reactome:REACT_22289} Q8NG41 Neuropeptide B protein 20080730 {GO:0005515=IPI, GO:0001664=IEA, GO:0007186=IDA, GO:0007218=IEA, GO:0005576=TAS} G-protein coupled receptor signaling pathway, neuropeptide signaling pathway extracellular region G-protein coupled receptor binding, protein binding Human NPBWR1 GOC UniProtKB {GO:0005515=PMID:12401809, GO:0005886=Reactome:REACT_22289, GO:0007186=PMID:12401809, GO:0019222=GO_REF:0000019, GO:0007268=PMID:7590751, GO:0038003=PMID:7590751, GO:0016021=PMID:12401809, GO:0008188=GO_REF:0000002, GO:0004985=PMID:7590751} P48145 Neuropeptides B/W receptor type 1 protein 20130413 {GO:0005515=IPI, GO:0005886=TAS, GO:0007186=IDA, GO:0019222=IEA, GO:0007268=TAS, GO:0038003=TAS, GO:0016021=IC, GO:0008188=IEA, GO:0004985=TAS} G-protein coupled receptor signaling pathway, opioid receptor signaling pathway, regulation of metabolic process, synaptic transmission integral to membrane, plasma membrane neuropeptide receptor activity, opioid receptor activity, protein binding Human NPBWR2 GOC UniProtKB {GO:0005515=PMID:12401809, GO:0005886=Reactome:REACT_22289, GO:0007186=PMID:12401809, GO:0038003=PMID:7590751, GO:0016021=PMID:12401809, GO:0008188=GO_REF:0000002, GO:0004985=PMID:7590751} P48146 Neuropeptides B/W receptor type 2 protein 20130413 {GO:0005515=IPI, GO:0005886=TAS, GO:0007186=IDA, GO:0038003=TAS, GO:0016021=IC, GO:0008188=IEA, GO:0004985=TAS} G-protein coupled receptor signaling pathway, opioid receptor signaling pathway integral to membrane, plasma membrane neuropeptide receptor activity, opioid receptor activity, protein binding Human NPC1 BHF-UCL UniProtKB {GO:0005515=PMID:19583955, GO:0015248=PMID:9927649, GO:0048471=PMID:12554680, GO:0005783=PMID:12554680, GO:0016242=GO_REF:0000019, GO:0030301=PMID:18772377, GO:0005635=PMID:12554680, GO:0005765=GO_REF:0000039, GO:0005764=GO_REF:0000024, GO:0015485=PMID:18772377, GO:0007628=GO_REF:0000019, GO:0004872=PMID:9211849, GO:0008206=GO_REF:0000024, GO:0008203=GO_REF:0000037, GO:0042632=PMID:12719428, GO:0033344=PMID:16141411, GO:0005794=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0006914=PMID:19074461, GO:0005576=GO_REF:0000024, GO:0031982=GO_REF:0000019, GO:0006897=GO_REF:0000019, GO:0071404=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0005887=PMID:10821832, GO:0071383=GO_REF:0000019, GO:0031902=GO_REF:0000039, GO:0008158=GO_REF:0000002, GO:0045121=GO_REF:0000019, GO:0007041=GO_REF:0000024, GO:0006486=PMID:10821832, GO:0016021=PMID:10521290, GO:0004888=PMID:10521290} O15118 Niemann-Pick C1 protein protein 20091124 {GO:0005515=IPI, GO:0015248=TAS, GO:0048471=IDA, GO:0005783=IDA, GO:0016242=IEA, GO:0030301=IDA, GO:0005635=IDA, GO:0005765=IEA, GO:0005764=ISS, GO:0015485=IDA, GO:0007628=IEA, GO:0004872=TAS, GO:0008206=ISS, GO:0008203=IEA, GO:0042632=IDA, GO:0033344=IDA, GO:0005794=IEA, GO:0042493=IEA, GO:0006914=IGI, GO:0005576=ISS, GO:0031982=IEA, GO:0006897=IEA, GO:0071404=IEA, GO:0016020=IEA, GO:0005887=IDA, GO:0071383=IEA, GO:0031902=IEA, GO:0008158=IEA, GO:0045121=IEA, GO:0007041=ISS, GO:0006486=IDA, GO:0016021=TAS, GO:0004888=TAS} adult walking behavior, autophagy, bile acid metabolic process, cellular response to low-density lipoprotein particle stimulus, cellular response to steroid hormone stimulus, cholesterol efflux, cholesterol homeostasis, cholesterol metabolic process, cholesterol transport, endocytosis, lysosomal transport, negative regulation of macroautophagy, protein glycosylation, response to drug Golgi apparatus, endoplasmic reticulum, extracellular region, integral to membrane, integral to plasma membrane, late endosome membrane, lysosomal membrane, lysosome, membrane, membrane raft, nuclear envelope, perinuclear region of cytoplasm, vesicle cholesterol binding, hedgehog receptor activity, protein binding, receptor activity, sterol transporter activity, transmembrane signaling receptor activity Human NPC2 BHF-UCL UniProtKB {GO:0042632=PMID:12719428, GO:0005515=PMID:19664597, GO:0033344=PMID:16141411, GO:0005783=GO_REF:0000039, GO:0019747=PMID:15110773, GO:0005576=GO_REF:0000039, GO:0030301=PMID:17018531, GO:0009615=PMID:16548883, GO:0005764=PMID:11125141, GO:0015914=PMID:17018531, GO:0015485=PMID:17018531, GO:0046836=PMID:17018531, GO:0019899=PMID:15110773, GO:0032367=PMID:17018531, GO:0032366=PMID:17018531, GO:0008203=GO_REF:0000037} P61916 Epididymal secretory protein E1 protein 20091124 {GO:0042632=IDA, GO:0005515=IPI, GO:0033344=IDA, GO:0005783=IEA, GO:0019747=TAS, GO:0005576=IEA, GO:0030301=IDA, GO:0009615=IEP, GO:0005764=IDA, GO:0015914=TAS, GO:0015485=IDA, GO:0046836=TAS, GO:0019899=IPI, GO:0032367=IDA, GO:0032366=IDA, GO:0008203=IEA} cholesterol efflux, cholesterol homeostasis, cholesterol metabolic process, cholesterol transport, glycolipid transport, intracellular cholesterol transport, intracellular sterol transport, phospholipid transport, regulation of isoprenoid metabolic process, response to virus endoplasmic reticulum, extracellular region, lysosome cholesterol binding, enzyme binding, protein binding Human NPDC1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9NQX5 Neural proliferation differentiation and control protein 1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 NPEPL1 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000002, GO:0030145=GO_REF:0000002, GO:0004177=GO_REF:0000037, GO:0008235=GO_REF:0000002, GO:0006508=GO_REF:0000037} Q8NDH3 Probable aminopeptidase NPEPL1 protein 20130413 {GO:0005622=IEA, GO:0005737=IEA, GO:0030145=IEA, GO:0004177=IEA, GO:0008235=IEA, GO:0006508=IEA} proteolysis cytoplasm, intracellular aminopeptidase activity, manganese ion binding, metalloexopeptidase activity Human UniProtKB-KW:KW-0645 NPEPPS Reactome UniProtKB {GO:0000209=Reactome:REACT_75842, GO:0002474=Reactome:REACT_75820, GO:0004177=GO_REF:0000037, GO:0006508=GO_REF:0000037, GO:0071456=PMID:21056661, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0008237=GO_REF:0000037, GO:0005829=Reactome:REACT_75931} P55786 Puromycin-sensitive aminopeptidase protein 20101029 {GO:0000209=TAS, GO:0002474=TAS, GO:0004177=IEA, GO:0006508=IEA, GO:0071456=IDA, GO:0005634=IEA, GO:0008270=IEA, GO:0008237=IEA, GO:0005829=TAS} antigen processing and presentation of peptide antigen via MHC class I, cellular response to hypoxia, protein polyubiquitination, proteolysis cytosol, nucleus aminopeptidase activity, metallopeptidase activity, zinc ion binding Human NPFF Reactome UniProtKB {GO:0002438=GO_REF:0000019, GO:0070253=GO_REF:0000019, GO:0021510=GO_REF:0000019, GO:0032099=GO_REF:0000019, GO:0007268=PMID:9224703, GO:0045777=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0007204=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0030103=GO_REF:0000019, GO:0007218=GO_REF:0000037, GO:0043204=GO_REF:0000019, GO:0043679=GO_REF:0000019, GO:0005184=GO_REF:0000019, GO:0046676=GO_REF:0000019, GO:0010459=GO_REF:0000019, GO:0001664=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0060135=GO_REF:0000019, GO:0060079=GO_REF:0000019, GO:0005102=PMID:9224703, GO:0043278=GO_REF:0000019, GO:0005576=Reactome:REACT_22436, GO:0031982=GO_REF:0000019, GO:0051930=GO_REF:0000019} O15130 FMRFamide-related peptides protein 20090107 {GO:0002438=IEA, GO:0070253=IEA, GO:0021510=IEA, GO:0032099=IEA, GO:0007268=TAS, GO:0045777=IEA, GO:0005615=IEA, GO:0007204=IEA, GO:0030425=IEA, GO:0030103=IEA, GO:0007218=IEA, GO:0043204=IEA, GO:0043679=IEA, GO:0005184=IEA, GO:0046676=IEA, GO:0010459=IEA, GO:0001664=IEA, GO:0042493=IEA, GO:0060135=IEA, GO:0060079=IEA, GO:0005102=TAS, GO:0043278=IEA, GO:0005576=TAS, GO:0031982=IEA, GO:0051930=IEA} acute inflammatory response to antigenic stimulus, elevation of cytosolic calcium ion concentration, maternal process involved in female pregnancy, negative regulation of appetite, negative regulation of heart rate, negative regulation of insulin secretion, neuropeptide signaling pathway, positive regulation of blood pressure, regulation of excitatory postsynaptic membrane potential, regulation of sensory perception of pain, response to drug, response to morphine, somatostatin secretion, spinal cord development, synaptic transmission, vasopressin secretion axon terminus, dendrite, extracellular region, extracellular space, perikaryon, vesicle G-protein coupled receptor binding, neuropeptide hormone activity, receptor binding Human NPFFR1 GOC UniProtKB {GO:0008150=GO_REF:0000015, GO:0005886=Reactome:REACT_22436, GO:0007218=PMID:11024015, GO:0004930=PMID:11024015, GO:0043408=GO_REF:0000002, GO:2000479=GO_REF:0000002, GO:0045761=GO_REF:0000002, GO:0031628=GO_REF:0000002, GO:0016021=GO_REF:0000029, GO:0008188=PMID:11024015} Q9GZQ6 Neuropeptide FF receptor 1 protein 20130413 {GO:0008150=ND, GO:0005886=TAS, GO:0007218=NAS, GO:0004930=NAS, GO:0043408=IEA, GO:2000479=IEA, GO:0045761=IEA, GO:0031628=IEA, GO:0016021=NAS, GO:0008188=NAS} biological_process, neuropeptide signaling pathway, regulation of MAPK cascade, regulation of adenylate cyclase activity, regulation of cAMP-dependent protein kinase activity integral to membrane, plasma membrane G-protein coupled receptor activity, neuropeptide receptor activity, opioid receptor binding Human NPFFR2 HPA UniProtKB {GO:0009582=PMID:10851242, GO:0005886=GO_REF:0000052, GO:0007186=PMID:10079187, GO:0005887=PMID:10079187, GO:0004930=PMID:10851242, GO:0043408=GO_REF:0000002, GO:2000479=GO_REF:0000002, GO:0045761=GO_REF:0000002, GO:0031628=GO_REF:0000002, GO:0015629=GO_REF:0000052, GO:0008188=GO_REF:0000002} Q9Y5X5 Neuropeptide FF receptor 2 protein 20101115 {GO:0009582=TAS, GO:0005886=IDA, GO:0007186=TAS, GO:0005887=TAS, GO:0004930=TAS, GO:0043408=IEA, GO:2000479=IEA, GO:0045761=IEA, GO:0031628=IEA, GO:0015629=IDA, GO:0008188=IEA} G-protein coupled receptor signaling pathway, detection of abiotic stimulus, regulation of MAPK cascade, regulation of adenylate cyclase activity, regulation of cAMP-dependent protein kinase activity actin cytoskeleton, integral to plasma membrane, plasma membrane G-protein coupled receptor activity, neuropeptide receptor activity, opioid receptor binding Human NPHP1 HGNC UniProtKB {GO:0005515=PMID:12872122, GO:0007588=PMID:9361039, GO:0030036=PMID:12006559, GO:0060041=GO_REF:0000024, GO:0031514=PMID:16885411, GO:0007632=PMID:12205563, GO:0048515=GO_REF:0000024, GO:0035085=GO_REF:0000039, GO:0035845=GO_REF:0000019, GO:0007165=PMID:12244321, GO:0016337=PMID:12006559, GO:0005912=GO_REF:0000039, GO:0016020=PMID:10665934, GO:0005911=PMID:21565611, GO:0005198=PMID:12006559, GO:0030030=GO_REF:0000024, GO:0032391=GO_REF:0000024, GO:0034613=GO_REF:0000019, GO:0005923=GO_REF:0000039, GO:0005856=GO_REF:0000037} O15259 Nephrocystin-1 protein 20071018 {GO:0005515=IPI, GO:0007588=TAS, GO:0030036=NAS, GO:0060041=ISS, GO:0031514=IDA, GO:0007632=NAS, GO:0048515=ISS, GO:0035085=IEA, GO:0035845=IEA, GO:0007165=NAS, GO:0016337=NAS, GO:0005912=IEA, GO:0016020=NAS, GO:0005911=IDA, GO:0005198=NAS, GO:0030030=ISS, GO:0032391=ISS, GO:0034613=IEA, GO:0005923=IEA, GO:0005856=IEA} actin cytoskeleton organization, cell projection organization, cell-cell adhesion, cellular protein localization, excretion, photoreceptor cell outer segment organization, retina development in camera-type eye, signal transduction, spermatid differentiation, visual behavior adherens junction, cell-cell junction, cilium axoneme, cytoskeleton, membrane, motile cilium, photoreceptor connecting cilium, tight junction protein binding, structural molecule activity Human UniProtKB:Q7Z494 NPHP3 BHF-UCL UniProtKB {GO:0006629=GO_REF:0000019, GO:0005515=PMID:22863007, GO:0007368=PMID:18371931, GO:0035469=PMID:20007846, GO:0003283=PMID:18371931, GO:2000167=PMID:18371931, GO:0071910=PMID:20007846, GO:0030324=PMID:20007846, GO:0001822=PMID:20007846, GO:2000095=GO_REF:0000024, GO:0072372=PMID:22085962, GO:0045494=PMID:12872122, GO:0048496=PMID:12872122, GO:0060287=GO_REF:0000036, GO:0001947=PMID:20007846, GO:0005929=PMID:20462968, GO:0060027=PMID:18371931, GO:0072189=PMID:18371931, GO:0060993=PMID:18371931, GO:0060271=GO_REF:0000024, GO:0016055=GO_REF:0000037, GO:0071909=PMID:18371931, GO:0090090=PMID:18371931, GO:0071908=PMID:20007846} Q7Z494 Nephrocystin-3 protein 20130307 {GO:0006629=IEA, GO:0005515=IPI, GO:0007368=IMP, GO:0035469=IMP, GO:0003283=IMP, GO:2000167=IC, GO:0071910=IMP, GO:0030324=IMP, GO:0001822=IMP, GO:2000095=ISS, GO:0072372=IDA, GO:0045494=IMP, GO:0048496=IMP, GO:0060287=IC, GO:0001947=IMP, GO:0005929=IDA, GO:0060027=IGI, GO:0072189=IMP, GO:0060993=IMP, GO:0060271=ISS, GO:0016055=IEA, GO:0071909=IMP, GO:0090090=IDA, GO:0071908=IMP} Wnt receptor signaling pathway, atrial septum development, cilium morphogenesis, convergent extension involved in gastrulation, determination of intestine left/right asymmetry, determination of left/right symmetry, determination of liver left/right asymmetry, determination of pancreatic left/right asymmetry, determination of stomach left/right asymmetry, epithelial cilium movement involved in determination of left/right asymmetry, heart looping, kidney development, kidney morphogenesis, lipid metabolic process, lung development, maintenance of organ identity, negative regulation of canonical Wnt receptor signaling pathway, photoreceptor cell maintenance, regulation of Wnt receptor signaling pathway, planar cell polarity pathway, regulation of planar cell polarity pathway involved in neural tube closure, ureter development cilium, primary cilium protein binding Human GO:0007368|GO:0060271 NPHP4 Reactome UniProtKB {GO:0005515=PMID:22863007, GO:0005813=PMID:21399614, GO:0030036=PMID:12006559, GO:0060041=GO_REF:0000019, GO:0007632=PMID:12205563, GO:0035329=Reactome:REACT_118607, GO:0005829=Reactome:REACT_118831, GO:0005929=GO_REF:0000037, GO:0007165=PMID:12244321, GO:0016337=PMID:12006559, GO:0016020=PMID:12006559, GO:0005198=PMID:12006559, GO:0005911=PMID:21565611, GO:0005923=GO_REF:0000039, GO:0005932=GO_REF:0000039} O75161 Nephrocystin-4 protein 20130213 {GO:0005515=IPI, GO:0005813=IDA, GO:0030036=NAS, GO:0060041=IEA, GO:0007632=NAS, GO:0035329=TAS, GO:0005829=TAS, GO:0005929=IEA, GO:0007165=NAS, GO:0016337=NAS, GO:0016020=IC, GO:0005198=NAS, GO:0005911=IDA, GO:0005923=IEA, GO:0005932=IEA} actin cytoskeleton organization, cell-cell adhesion, hippo signaling cascade, retina development in camera-type eye, signal transduction, visual behavior cell-cell junction, centrosome, cilium, cytosol, membrane, microtubule basal body, tight junction protein binding, structural molecule activity Human NPHS1 IntAct UniProtKB {GO:0005515=PMID:16525419, GO:0007588=PMID:9660941, GO:0005886=Reactome:REACT_24018, GO:0072015=PMID:17464107, GO:0007254=GO_REF:0000019, GO:0007520=GO_REF:0000019, GO:0042995=GO_REF:0000019, GO:0032836=PMID:17464107, GO:0030838=GO_REF:0000019, GO:0005887=PMID:9660941, GO:0036057=GO_REF:0000024, GO:0007155=GO_REF:0000019, GO:0044062=GO_REF:0000019} O60500 Nephrin protein 20130415 {GO:0005515=IPI, GO:0007588=TAS, GO:0005886=TAS, GO:0072015=IEP, GO:0007254=IEA, GO:0007520=IEA, GO:0042995=IEA, GO:0032836=IEP, GO:0030838=IEA, GO:0005887=TAS, GO:0036057=ISS, GO:0007155=IEA, GO:0044062=IEA} JNK cascade, cell adhesion, excretion, glomerular basement membrane development, glomerular visceral epithelial cell development, myoblast fusion, positive regulation of actin filament polymerization, regulation of excretion cell projection, integral to plasma membrane, plasma membrane, slit diaphragm protein binding Human UniProtKB:P16333 NPHS2 Reactome UniProtKB {GO:0005515=PMID:17675666, GO:0007588=PMID:10742096, GO:0043234=PMID:17675666, GO:0005886=Reactome:REACT_23984, GO:0072249=PMID:11786407, GO:0031532=PMID:17675666, GO:0005887=PMID:10742096, GO:0005911=PMID:17675666, GO:0036057=PMID:11786407, GO:0031235=PMID:11786407, GO:0045121=PMID:17675666} Q9NP85 Podocin protein 20120323 {GO:0005515=IPI, GO:0007588=TAS, GO:0043234=IDA, GO:0005886=TAS, GO:0072249=IEP, GO:0031532=IDA, GO:0005887=TAS, GO:0005911=IDA, GO:0036057=IDA, GO:0031235=IDA, GO:0045121=IDA} actin cytoskeleton reorganization, excretion, metanephric glomerular visceral epithelial cell development cell-cell junction, integral to plasma membrane, intrinsic to internal side of plasma membrane, membrane raft, plasma membrane, protein complex, slit diaphragm protein binding Human NPIP UniProtKB UniProtKB {GO:0031965=GO_REF:0000039, GO:0005643=GO_REF:0000039, GO:0051028=GO_REF:0000037, GO:0015031=GO_REF:0000037} Q9UND3 Nuclear pore complex-interacting protein protein 20130413 {GO:0031965=IEA, GO:0005643=IEA, GO:0051028=IEA, GO:0015031=IEA} mRNA transport, protein transport nuclear membrane, nuclear pore Human UniProtKB-SubCell:SL-0182 NPL UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0008747=GO_REF:0000024, GO:0005975=GO_REF:0000037, GO:0019262=PMID:22692205, GO:0016829=GO_REF:0000002} Q9BXD5 N-acetylneuraminate lyase protein 20121102 {GO:0005737=IEA, GO:0008747=ISS, GO:0005975=IEA, GO:0019262=TAS, GO:0016829=IEA} N-acetylneuraminate catabolic process, carbohydrate metabolic process cytoplasm N-acetylneuraminate lyase activity, lyase activity Human NPLOC4 HGNC UniProtKB {GO:0005515=PMID:11574150, GO:0006944=PMID:11574150, GO:0005783=PMID:11574150, GO:0042175=PMID:11574150, GO:0007030=PMID:11574150, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0030433=PMID:11574150, GO:0005829=GO_REF:0000039} Q8TAT6 Nuclear protein localization protein 4 homolog protein 20060221 {GO:0005515=IPI, GO:0006944=ISS, GO:0005783=ISS, GO:0042175=ISS, GO:0007030=ISS, GO:0005634=IEA, GO:0008270=IEA, GO:0030433=ISS, GO:0005829=IEA} ER-associated protein catabolic process, Golgi organization, cellular membrane fusion cytosol, endoplasmic reticulum, nuclear outer membrane-endoplasmic reticulum membrane network, nucleus protein binding, zinc ion binding Human UniProtKB:P33755 NPM1 HPA UniProtKB {GO:0005515=PMID:15144954, GO:0008285=GO_REF:0000024, GO:0007098=PMID:11051553, GO:0003723=PMID:12058066, GO:0032071=PMID:19188445, GO:0060699=PMID:19188445, GO:0005634=GO_REF:0000052, GO:0046599=PMID:20352051, GO:0051259=PMID:18809582, GO:0006886=PMID:12080348, GO:0042803=PMID:9121481, GO:0005829=Reactome:REACT_9511, GO:0042393=PMID:11602260, GO:0005737=GO_REF:0000024, GO:0051092=PMID:15087454, GO:0008104=PMID:18420587, GO:0016032=Reactome:REACT_6185, GO:0043023=PMID:18809582, GO:0043024=PMID:18809582, GO:0043066=PMID:16130169, GO:0005813=GO_REF:0000024, GO:0019901=PMID:20352051, GO:0046982=PMID:12080348, GO:0051059=GO_REF:0000024, GO:0042255=PMID:12080348, GO:0007569=GO_REF:0000024, GO:0003713=PMID:15087454, GO:0005730=GO_REF:0000052, GO:0006334=Reactome:REACT_22344, GO:0006950=PMID:12080348, GO:0010826=PMID:16041368, GO:0003676=GO_REF:0000002, GO:0030957=PMID:9094689, GO:0006913=PMID:16041368, GO:0034080=Reactome:REACT_22186, GO:0007165=PMID:16130169, GO:0006281=PMID:19188445, GO:0030529=PMID:18809582, GO:0019048=GO_REF:0000037, GO:0005654=Reactome:REACT_22217, GO:0031616=PMID:16041368, GO:0051082=GO_REF:0000024} P06748 Nucleophosmin protein 20101115 {GO:0005515=IPI, GO:0008285=ISS, GO:0007098=IMP, GO:0003723=IDA, GO:0032071=IDA, GO:0060699=IDA, GO:0005634=IDA, GO:0046599=IMP, GO:0051259=IDA, GO:0006886=TAS, GO:0042803=IDA, GO:0005829=TAS, GO:0042393=IDA, GO:0005737=ISS, GO:0051092=IMP, GO:0008104=IDA, GO:0016032=TAS, GO:0043023=IDA, GO:0043024=IDA, GO:0043066=NAS, GO:0005813=ISS, GO:0019901=IPI, GO:0046982=IMP, GO:0051059=ISS, GO:0042255=TAS, GO:0007569=ISS, GO:0003713=IDA, GO:0005730=IDA, GO:0006334=TAS, GO:0006950=IMP, GO:0010826=IMP, GO:0003676=IEA, GO:0030957=IDA, GO:0006913=IDA, GO:0034080=TAS, GO:0007165=NAS, GO:0006281=IDA, GO:0030529=IDA, GO:0019048=IEA, GO:0005654=TAS, GO:0031616=IDA, GO:0051082=ISS} CENP-A containing nucleosome assembly at centromere, DNA repair, cell aging, centrosome cycle, intracellular protein transport, negative regulation of apoptotic process, negative regulation of cell proliferation, negative regulation of centrosome duplication, nucleocytoplasmic transport, nucleosome assembly, positive regulation of NF-kappaB transcription factor activity, protein localization, protein oligomerization, regulation of centriole replication, regulation of endodeoxyribonuclease activity, regulation of endoribonuclease activity, response to stress, ribosome assembly, signal transduction, viral reproduction, virus-host interaction centrosome, cytoplasm, cytosol, nucleolus, nucleoplasm, nucleus, ribonucleoprotein complex, spindle pole centrosome NF-kappaB binding, RNA binding, Tat protein binding, histone binding, nucleic acid binding, protein binding, protein heterodimerization activity, protein homodimerization activity, protein kinase binding, ribosomal large subunit binding, ribosomal small subunit binding, transcription coactivator activity, unfolded protein binding Human NPM3 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0009303=GO_REF:0000019, GO:0006364=GO_REF:0000019, GO:0005730=GO_REF:0000019, GO:0003676=GO_REF:0000002} O75607 Nucleoplasmin-3 protein 20130415 {GO:0005515=IPI, GO:0009303=IEA, GO:0006364=IEA, GO:0005730=IEA, GO:0003676=IEA} rRNA processing, rRNA transcription nucleolus nucleic acid binding, protein binding Human UniProtKB:P04608 NPNT BHF-UCL UniProtKB {GO:0001657=PMID:15754038, GO:0001658=PMID:15754038, GO:2000721=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0010811=PMID:15754038, GO:0005578=GO_REF:0000024, GO:0097195=GO_REF:0000019, GO:0005576=PMID:15754038, GO:0033631=PMID:15754038, GO:0034678=GO_REF:0000019, GO:0030154=GO_REF:0000037, GO:0030485=GO_REF:0000019, GO:0045184=GO_REF:0000019, GO:0005604=GO_REF:0000019, GO:0045669=PMID:15754038, GO:0005178=PMID:15754038, GO:0016020=GO_REF:0000002, GO:0007160=PMID:15754038, GO:0045987=GO_REF:0000019, GO:0030198=PMID:15754038, GO:0071356=PMID:15754038, GO:0010694=GO_REF:0000019, GO:0070374=GO_REF:0000019, GO:0030511=GO_REF:0000019} Q6UXI9 Nephronectin protein 20120319 {GO:0001657=ISS, GO:0001658=ISS, GO:2000721=IEA, GO:0005509=IEA, GO:0010811=ISS, GO:0005578=ISS, GO:0097195=IEA, GO:0005576=ISS, GO:0033631=ISS, GO:0034678=IEA, GO:0030154=IEA, GO:0030485=IEA, GO:0045184=IEA, GO:0005604=IEA, GO:0045669=ISS, GO:0005178=ISS, GO:0016020=IEA, GO:0007160=ISS, GO:0045987=IEA, GO:0030198=ISS, GO:0071356=ISS, GO:0010694=IEA, GO:0070374=IEA, GO:0030511=IEA} branching involved in ureteric bud morphogenesis, cell differentiation, cell-cell adhesion mediated by integrin, cell-matrix adhesion, cellular response to tumor necrosis factor, establishment of protein localization, extracellular matrix organization, pilomotor reflex, positive regulation of ERK1 and ERK2 cascade, positive regulation of alkaline phosphatase activity, positive regulation of cell-substrate adhesion, positive regulation of osteoblast differentiation, positive regulation of smooth muscle contraction, positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation, positive regulation of transforming growth factor beta receptor signaling pathway, ureteric bud development alpha8-beta1 integrin complex, basement membrane, extracellular region, membrane, proteinaceous extracellular matrix, smooth muscle contractile fiber calcium ion binding, integrin binding Human UniProtKB:Q91V88 NPPA Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0032868=GO_REF:0000019, GO:0007565=GO_REF:0000024, GO:0030308=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0006367=Reactome:REACT_118713, GO:0005102=PMID:1672777, GO:0005576=Reactome:REACT_118863, GO:0005634=GO_REF:0000019, GO:0051428=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0042629=GO_REF:0000019, GO:0050880=GO_REF:0000037, GO:0005179=GO_REF:0000029, GO:0006182=PMID:1672777, GO:0014898=GO_REF:0000019, GO:0008217=PMID:6230082, GO:0007168=PMID:1672777} P01160 Natriuretic peptides A protein 20130301 {GO:0010467=TAS, GO:0032868=IEA, GO:0007565=ISS, GO:0030308=IEA, GO:0048471=IEA, GO:0006367=TAS, GO:0005102=IDA, GO:0005576=TAS, GO:0005634=IEA, GO:0051428=IEA, GO:0005615=IEA, GO:0042629=IEA, GO:0050880=IEA, GO:0005179=NAS, GO:0006182=IDA, GO:0014898=IEA, GO:0008217=IDA, GO:0007168=IDA} cGMP biosynthetic process, cardiac muscle hypertrophy in response to stress, female pregnancy, gene expression, negative regulation of cell growth, receptor guanylyl cyclase signaling pathway, regulation of blood pressure, regulation of blood vessel size, response to insulin stimulus, transcription initiation from RNA polymerase II promoter extracellular region, extracellular space, mast cell granule, nucleus, perinuclear region of cytoplasm hormone activity, peptide hormone receptor binding, receptor binding Human NPPB UniProtKB UniProtKB {GO:0014070=GO_REF:0000019, GO:0030308=PMID:12727915, GO:0048471=GO_REF:0000019, GO:0043434=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0051428=GO_REF:0000019, GO:0005615=PMID:7601467, GO:0007507=GO_REF:0000019, GO:0042312=PMID:7601467, GO:0006954=GO_REF:0000019, GO:0050880=GO_REF:0000037, GO:0032496=GO_REF:0000019, GO:0007589=PMID:14960748, GO:0001666=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0008613=PMID:14960748, GO:0005102=PMID:1660465, GO:0005576=PMID:14960748, GO:0048662=GO_REF:0000019, GO:0051592=GO_REF:0000019, GO:0005179=PMID:7601467, GO:0006182=PMID:1672777, GO:0016525=PMID:14737067, GO:0035815=PMID:14960748, GO:0043114=PMID:14737067, GO:0008217=PMID:12727915, GO:0007168=PMID:1672777, GO:0071260=GO_REF:0000019, GO:0035810=PMID:14737067, GO:0007166=PMID:12727915} P16860 Natriuretic peptides B protein 20100121 {GO:0014070=IEA, GO:0030308=NAS, GO:0048471=IEA, GO:0043434=IEA, GO:0005634=IEA, GO:0051428=IEA, GO:0005615=NAS, GO:0007507=IEA, GO:0042312=NAS, GO:0006954=IEA, GO:0050880=IEA, GO:0032496=IEA, GO:0007589=TAS, GO:0001666=IEA, GO:0042493=IEA, GO:0008613=TAS, GO:0005102=IPI, GO:0005576=TAS, GO:0048662=IEA, GO:0051592=IEA, GO:0005179=NAS, GO:0006182=IDA, GO:0016525=TAS, GO:0035815=TAS, GO:0043114=TAS, GO:0008217=NAS, GO:0007168=IDA, GO:0071260=IEA, GO:0035810=TAS, GO:0007166=NAS} body fluid secretion, cGMP biosynthetic process, cell surface receptor signaling pathway, cellular response to mechanical stimulus, heart development, inflammatory response, negative regulation of angiogenesis, negative regulation of cell growth, negative regulation of smooth muscle cell proliferation, positive regulation of renal sodium excretion, positive regulation of urine volume, receptor guanylyl cyclase signaling pathway, regulation of blood pressure, regulation of blood vessel size, regulation of vascular permeability, regulation of vasodilation, response to calcium ion, response to drug, response to hypoxia, response to lipopolysaccharide, response to organic cyclic compound, response to peptide hormone stimulus extracellular region, extracellular space, nucleus, perinuclear region of cytoplasm diuretic hormone activity, hormone activity, peptide hormone receptor binding, receptor binding Human NPPC UniProtKB UniProtKB {GO:0003419=GO_REF:0000024, GO:0003418=GO_REF:0000024, GO:0008285=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0051428=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0019229=GO_REF:0000029, GO:0050880=GO_REF:0000037, GO:0045909=GO_REF:0000019, GO:0040014=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0051053=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0005102=PMID:1672777, GO:0005576=GO_REF:0000029, GO:0048660=GO_REF:0000019, GO:0045669=GO_REF:0000019, GO:0005179=GO_REF:0000019, GO:0001503=GO_REF:0000037, GO:0006182=PMID:1672777, GO:0008217=GO_REF:0000029, GO:0030828=GO_REF:0000019, GO:0007168=PMID:1672777} P23582 C-type natriuretic peptide protein 20100203 {GO:0003419=ISS, GO:0003418=ISS, GO:0008285=IEA, GO:0045471=IEA, GO:0009791=IEA, GO:0051428=IEA, GO:0005615=IEA, GO:0042803=IEA, GO:0019229=NAS, GO:0050880=IEA, GO:0045909=IEA, GO:0040014=IEA, GO:0001666=IEA, GO:0051053=IEA, GO:0042493=IEA, GO:0005102=IPI, GO:0005576=NAS, GO:0048660=IEA, GO:0045669=IEA, GO:0005179=IEA, GO:0001503=IEA, GO:0006182=IDA, GO:0008217=NAS, GO:0030828=IEA, GO:0007168=IDA} cGMP biosynthetic process, growth plate cartilage chondrocyte differentiation, growth plate cartilage chondrocyte proliferation, negative regulation of DNA metabolic process, negative regulation of cell proliferation, ossification, positive regulation of cGMP biosynthetic process, positive regulation of osteoblast differentiation, positive regulation of vasodilation, post-embryonic development, receptor guanylyl cyclase signaling pathway, regulation of blood pressure, regulation of blood vessel size, regulation of multicellular organism growth, regulation of smooth muscle cell proliferation, regulation of vasoconstriction, response to drug, response to ethanol, response to hypoxia extracellular region, extracellular space hormone activity, peptide hormone receptor binding, protein homodimerization activity, receptor binding Human UniProtKB:Q61839 NPR1 UniProtKB UniProtKB {GO:0030308=PMID:12727915, GO:0042562=PMID:1660465, GO:0008528=PMID:12547834, GO:0035556=GO_REF:0000019, GO:0042312=PMID:7601467, GO:0016941=PMID:1672777, GO:0042417=GO_REF:0000019, GO:0050880=GO_REF:0000037, GO:0000166=GO_REF:0000038, GO:0007589=PMID:14960748, GO:0019901=GO_REF:0000019, GO:0016849=GO_REF:0000002, GO:0048662=GO_REF:0000019, GO:0004383=PMID:1672777, GO:0005525=GO_REF:0000019, GO:0005524=GO_REF:0000002, GO:0004672=GO_REF:0000002, GO:0005887=PMID:12547834, GO:0006182=PMID:1672777, GO:0016525=PMID:14737067, GO:0035815=PMID:14960748, GO:0008217=PMID:12727915, GO:0043114=PMID:14737067, GO:0030828=GO_REF:0000019, GO:0007168=PMID:1672777, GO:0009190=GO_REF:0000002, GO:0035810=PMID:14737067, GO:0017046=GO_REF:0000019, GO:0007166=PMID:12547834} P16066 Atrial natriuretic peptide receptor 1 protein 20100121 {GO:0030308=NAS, GO:0042562=IPI, GO:0008528=NAS, GO:0035556=IEA, GO:0042312=NAS, GO:0016941=IDA, GO:0042417=IEA, GO:0050880=IEA, GO:0000166=IEA, GO:0007589=TAS, GO:0019901=IEA, GO:0016849=IEA, GO:0048662=IEA, GO:0004383=IDA, GO:0005525=IEA, GO:0005524=IEA, GO:0004672=IEA, GO:0005887=IC, GO:0006182=IDA, GO:0016525=TAS, GO:0035815=TAS, GO:0008217=NAS, GO:0043114=TAS, GO:0030828=IEA, GO:0007168=IDA, GO:0009190=IEA, GO:0035810=TAS, GO:0017046=IEA, GO:0007166=NAS} body fluid secretion, cGMP biosynthetic process, cell surface receptor signaling pathway, cyclic nucleotide biosynthetic process, dopamine metabolic process, intracellular signal transduction, negative regulation of angiogenesis, negative regulation of cell growth, negative regulation of smooth muscle cell proliferation, positive regulation of cGMP biosynthetic process, positive regulation of renal sodium excretion, positive regulation of urine volume, receptor guanylyl cyclase signaling pathway, regulation of blood pressure, regulation of blood vessel size, regulation of vascular permeability, regulation of vasodilation integral to plasma membrane ATP binding, G-protein coupled peptide receptor activity, GTP binding, guanylate cyclase activity, hormone binding, natriuretic peptide receptor activity, nucleotide binding, peptide hormone binding, phosphorus-oxygen lyase activity, protein kinase activity, protein kinase binding Human NPR2 PINC UniProtKB {GO:0016849=GO_REF:0000002, GO:0005886=GO_REF:0000019, GO:0042562=PMID:1660465, GO:0004383=PMID:1672777, GO:0005525=GO_REF:0000019, GO:0005524=GO_REF:0000019, GO:0042802=GO_REF:0000019, GO:0035556=GO_REF:0000002, GO:0007165=PMID:10082481, GO:0060348=GO_REF:0000019, GO:0016941=PMID:1672777, GO:0004672=GO_REF:0000002, GO:0001503=GO_REF:0000037, GO:0006182=PMID:1672777, GO:0008217=PMID:10082481, GO:0004872=PMID:10082481, GO:0097011=PMID:14687666, GO:0016021=GO_REF:0000037, GO:0007168=PMID:1672777, GO:0009190=GO_REF:0000002, GO:0017046=GO_REF:0000019, GO:0007166=PMID:1327579, GO:0004888=PMID:1327579} P20594 Atrial natriuretic peptide receptor 2 protein 20030904 {GO:0016849=IEA, GO:0005886=IEA, GO:0042562=IPI, GO:0004383=IDA, GO:0005525=IEA, GO:0005524=IEA, GO:0042802=IEA, GO:0035556=IEA, GO:0007165=NAS, GO:0060348=IEA, GO:0016941=IDA, GO:0004672=IEA, GO:0001503=IEA, GO:0006182=IDA, GO:0008217=TAS, GO:0004872=TAS, GO:0097011=IEP, GO:0016021=IEA, GO:0007168=IDA, GO:0009190=IEA, GO:0017046=IEA, GO:0007166=TAS, GO:0004888=TAS} bone development, cGMP biosynthetic process, cell surface receptor signaling pathway, cellular response to granulocyte macrophage colony-stimulating factor stimulus, cyclic nucleotide biosynthetic process, intracellular signal transduction, ossification, receptor guanylyl cyclase signaling pathway, regulation of blood pressure, signal transduction integral to membrane, plasma membrane ATP binding, GTP binding, guanylate cyclase activity, hormone binding, identical protein binding, natriuretic peptide receptor activity, peptide hormone binding, phosphorus-oxygen lyase activity, protein kinase activity, receptor activity, transmembrane signaling receptor activity Human NPR3 BHF-UCL UniProtKB {GO:0033688=GO_REF:0000024, GO:0042562=PMID:1660465, GO:0008528=GO_REF:0000024, GO:0007200=GO_REF:0000019, GO:0007194=GO_REF:0000019, GO:0007193=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0001501=GO_REF:0000024, GO:0016941=PMID:1660465, GO:0005887=PMID:1660465, GO:0051000=GO_REF:0000024, GO:0008217=GO_REF:0000024, GO:0016021=GO_REF:0000002, GO:0002158=GO_REF:0000024, GO:0017046=GO_REF:0000024, GO:0035810=GO_REF:0000024} P17342 Atrial natriuretic peptide receptor 3 protein 20120510 {GO:0033688=ISS, GO:0042562=IPI, GO:0008528=ISS, GO:0007200=IEA, GO:0007194=IEA, GO:0007193=IEA, GO:0042803=IEA, GO:0001501=ISS, GO:0016941=IDA, GO:0005887=IC, GO:0051000=ISS, GO:0008217=ISS, GO:0016021=IEA, GO:0002158=ISS, GO:0017046=ISS, GO:0035810=ISS} adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, negative regulation of adenylate cyclase activity, osteoclast proliferation, phospholipase C-activating G-protein coupled receptor signaling pathway, positive regulation of nitric-oxide synthase activity, positive regulation of urine volume, regulation of blood pressure, regulation of osteoblast proliferation, skeletal system development integral to membrane, integral to plasma membrane G-protein coupled peptide receptor activity, hormone binding, natriuretic peptide receptor activity, peptide hormone binding, protein homodimerization activity Human GO:0016941 NPRL2 GOC UniProtKB {GO:0005515=PMID:18616680, GO:0033673=PMID:18616680, GO:0005737=GO_REF:0000052, GO:0004672=PMID:18616680, GO:0006468=PMID:18616680} Q8WTW4 Nitrogen permease regulator 2-like protein protein 20130413 {GO:0005515=IPI, GO:0033673=IDA, GO:0005737=IDA, GO:0004672=IDA, GO:0006468=IDA} negative regulation of kinase activity, protein phosphorylation cytoplasm protein binding, protein kinase activity Human NPRL3 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q12980 Nitrogen permease regulator 3-like protein protein 20080829 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human NPS Reactome UniProtKB {GO:0007218=GO_REF:0000037, GO:0008542=GO_REF:0000019, GO:0051968=GO_REF:0000019, GO:0005576=Reactome:REACT_22436, GO:0045760=GO_REF:0000019, GO:0032230=GO_REF:0000019} P0C0P6 Neuropeptide S protein 20130213 {GO:0007218=IEA, GO:0008542=IEA, GO:0051968=IEA, GO:0005576=TAS, GO:0045760=IEA, GO:0032230=IEA} neuropeptide signaling pathway, positive regulation of action potential, positive regulation of synaptic transmission, GABAergic, positive regulation of synaptic transmission, glutamatergic, visual learning extracellular region Human NPSR1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005000=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0008188=GO_REF:0000002} Q6W5P4 Neuropeptide S receptor protein 20101115 {GO:0005737=IDA, GO:0005886=IDA, GO:0005000=IEA, GO:0016021=IEA, GO:0008188=IEA} cytoplasm, integral to membrane, plasma membrane neuropeptide receptor activity, vasopressin receptor activity Human NPTN HGNC UniProtKB {GO:0042734=GO_REF:0000024, GO:0045743=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0010976=GO_REF:0000024, GO:0001934=GO_REF:0000024, GO:0060291=GO_REF:0000024, GO:0005105=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0050839=GO_REF:0000024, GO:0007156=GO_REF:0000024, GO:0007204=GO_REF:0000024, GO:0048170=GO_REF:0000024} Q9Y639 Neuroplastin protein 20060131 {GO:0042734=ISS, GO:0045743=ISS, GO:0005886=IEA, GO:0010976=ISS, GO:0001934=ISS, GO:0060291=ISS, GO:0005105=ISS, GO:0016021=IEA, GO:0050839=ISS, GO:0007156=ISS, GO:0007204=ISS, GO:0048170=ISS} elevation of cytosolic calcium ion concentration, homophilic cell adhesion, long-term synaptic potentiation, positive regulation of fibroblast growth factor receptor signaling pathway, positive regulation of long-term neuronal synaptic plasticity, positive regulation of neuron projection development, positive regulation of protein phosphorylation integral to membrane, plasma membrane, presynaptic membrane cell adhesion molecule binding, type 1 fibroblast growth factor receptor binding Human UniProtKB:P97546 NPTX1 PINC UniProtKB {GO:0030133=GO_REF:0000039, GO:0060385=GO_REF:0000019, GO:0006810=PMID:8884281, GO:0007268=PMID:8884281, GO:0007417=PMID:8884281, GO:0046872=GO_REF:0000037} Q15818 Neuronal pentraxin-1 protein 20030904 {GO:0030133=IEA, GO:0060385=IEA, GO:0006810=TAS, GO:0007268=TAS, GO:0007417=TAS, GO:0046872=IEA} axonogenesis involved in innervation, central nervous system development, synaptic transmission, transport transport vesicle metal ion binding Human NPTX2 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0007268=PMID:8530029, GO:0005576=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0046872=GO_REF:0000037} P47972 Neuronal pentraxin-2 protein 20061026 {GO:0003674=ND, GO:0007268=NAS, GO:0005576=IEA, GO:0005575=ND, GO:0046872=IEA} synaptic transmission cellular_component, extracellular region metal ion binding, molecular_function Human NPTXR UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0046872=GO_REF:0000037} O95502 Neuronal pentraxin receptor protein 20130413 {GO:0016021=IEA, GO:0046872=IEA} integral to membrane metal ion binding Human UniProtKB-KW:KW-0479 NPVF UniProtKB UniProtKB {GO:0016020=GO_REF:0000029, GO:0007218=PMID:11025660, GO:0004930=GO_REF:0000029, GO:0005576=GO_REF:0000039, GO:0032277=PMID:20027225} Q9HCQ7 FMRFamide-related peptides protein 20111206 {GO:0016020=NAS, GO:0007218=NAS, GO:0004930=NAS, GO:0005576=IEA, GO:0032277=IDA} negative regulation of gonadotropin secretion, neuropeptide signaling pathway extracellular region, membrane G-protein coupled receptor activity Human NPW Reactome UniProtKB {GO:0005515=PMID:12401809, GO:0007631=PMID:12959997, GO:0001664=GO_REF:0000019, GO:0007186=PMID:12401809, GO:0007218=GO_REF:0000037, GO:0005576=Reactome:REACT_22289} Q8N729 Neuropeptide W protein 20080730 {GO:0005515=IPI, GO:0007631=IDA, GO:0001664=IEA, GO:0007186=IDA, GO:0007218=IEA, GO:0005576=TAS} G-protein coupled receptor signaling pathway, feeding behavior, neuropeptide signaling pathway extracellular region G-protein coupled receptor binding, protein binding Human NPY Reactome UniProtKB {GO:0008343=GO_REF:0000024, GO:0007631=PMID:10698177, GO:0001664=GO_REF:0000019, GO:0021987=PMID:9067840, GO:0008283=PMID:10488139, GO:0004930=PMID:1321422, GO:0005246=PMID:8132547, GO:0008015=PMID:8421707, GO:0007586=PMID:8421707, GO:0032100=GO_REF:0000024, GO:0021954=PMID:20846339, GO:0005102=PMID:8132547, GO:0005623=PMID:2444979, GO:0007268=PMID:10557353, GO:0006928=PMID:10488139, GO:0005576=Reactome:REACT_22289, GO:0005615=GO_REF:0000024, GO:0031175=PMID:20846339, GO:0007187=PMID:8132547, GO:0007218=GO_REF:0000037, GO:0008217=GO_REF:0000019, GO:0007610=PMID:9845072, GO:0006816=PMID:8132547, GO:0005184=PMID:2427515} P01303 Pro-neuropeptide Y protein 20081217 {GO:0008343=ISS, GO:0007631=TAS, GO:0001664=IEA, GO:0021987=IEP, GO:0008283=TAS, GO:0004930=TAS, GO:0005246=TAS, GO:0008015=NAS, GO:0007586=NAS, GO:0032100=ISS, GO:0021954=IEP, GO:0005102=TAS, GO:0005623=TAS, GO:0007268=TAS, GO:0006928=TAS, GO:0005576=TAS, GO:0005615=ISS, GO:0031175=IEP, GO:0007187=TAS, GO:0007218=IEA, GO:0008217=IEA, GO:0007610=TAS, GO:0006816=TAS, GO:0005184=TAS} G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, adult feeding behavior, behavior, blood circulation, calcium ion transport, cell proliferation, cellular component movement, central nervous system neuron development, cerebral cortex development, digestion, feeding behavior, neuron projection development, neuropeptide signaling pathway, positive regulation of appetite, regulation of blood pressure, synaptic transmission cell, extracellular region, extracellular space G-protein coupled receptor activity, G-protein coupled receptor binding, calcium channel regulator activity, neuropeptide hormone activity, receptor binding Human NPY1R BHF-UCL UniProtKB {GO:0007631=GO_REF:0000019, GO:0005886=Reactome:REACT_22289, GO:0007193=PMID:1321422, GO:0003151=PMID:19593212, GO:0019233=GO_REF:0000019, GO:0004983=PMID:1317848, GO:0005887=PMID:1317848, GO:0007187=PMID:1317848, GO:0040014=GO_REF:0000019, GO:0001602=GO_REF:0000019, GO:0008217=GO_REF:0000019, GO:0001601=GO_REF:0000019, GO:0006006=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0016021=GO_REF:0000002} P25929 Neuropeptide Y receptor type 1 protein 20100819 {GO:0007631=IEA, GO:0005886=TAS, GO:0007193=TAS, GO:0003151=IMP, GO:0019233=IEA, GO:0004983=TAS, GO:0005887=TAS, GO:0007187=TAS, GO:0040014=IEA, GO:0001602=IEA, GO:0008217=IEA, GO:0001601=IEA, GO:0006006=IEA, GO:0007626=IEA, GO:0016021=IEA} G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, feeding behavior, glucose metabolic process, locomotory behavior, outflow tract morphogenesis, regulation of blood pressure, regulation of multicellular organism growth, sensory perception of pain integral to membrane, integral to plasma membrane, plasma membrane neuropeptide Y receptor activity, pancreatic polypeptide receptor activity, peptide YY receptor activity Human NPY2R BHF-UCL UniProtKB {GO:0004983=PMID:7559383, GO:0005886=Reactome:REACT_22289, GO:0005887=PMID:7592910, GO:0005246=PMID:8132547, GO:0001601=GO_REF:0000019, GO:0007626=PMID:9692752, GO:0004872=PMID:1321422, GO:0003214=PMID:19593212, GO:0007193=PMID:7559383, GO:0003151=PMID:19593212} P49146 Neuropeptide Y receptor type 2 protein 20100819 {GO:0004983=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0005246=TAS, GO:0001601=IEA, GO:0007626=TAS, GO:0004872=TAS, GO:0003214=IMP, GO:0007193=TAS, GO:0003151=IMP} adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, cardiac left ventricle morphogenesis, locomotory behavior, outflow tract morphogenesis integral to plasma membrane, plasma membrane calcium channel regulator activity, neuropeptide Y receptor activity, peptide YY receptor activity, receptor activity Human NPY5R BHF-UCL UniProtKB {GO:0060112=GO_REF:0000019, GO:0005886=Reactome:REACT_22289, GO:0014050=GO_REF:0000019, GO:0003214=PMID:19593212, GO:0048661=GO_REF:0000019, GO:0003151=PMID:19593212, GO:0005737=GO_REF:0000019, GO:0004983=PMID:8824284, GO:0002675=GO_REF:0000019, GO:0007186=PMID:8824284, GO:0005887=PMID:8824284, GO:0001602=GO_REF:0000019, GO:0001601=GO_REF:0000019, GO:0032229=GO_REF:0000019, GO:0042755=GO_REF:0000019} Q15761 Neuropeptide Y receptor type 5 protein 20100819 {GO:0060112=IEA, GO:0005886=TAS, GO:0014050=IEA, GO:0003214=IMP, GO:0048661=IEA, GO:0003151=IMP, GO:0005737=IEA, GO:0004983=TAS, GO:0002675=IEA, GO:0007186=TAS, GO:0005887=TAS, GO:0001602=IEA, GO:0001601=IEA, GO:0032229=IEA, GO:0042755=IEA} G-protein coupled receptor signaling pathway, cardiac left ventricle morphogenesis, eating behavior, generation of ovulation cycle rhythm, negative regulation of glutamate secretion, negative regulation of synaptic transmission, GABAergic, outflow tract morphogenesis, positive regulation of acute inflammatory response, positive regulation of smooth muscle cell proliferation cytoplasm, integral to plasma membrane, plasma membrane neuropeptide Y receptor activity, pancreatic polypeptide receptor activity, peptide YY receptor activity Human NQO1 HPA UniProtKB {GO:0005515=PMID:21042282, GO:0006805=PMID:10393963, GO:0004128=PMID:9579781, GO:0007584=GO_REF:0000019, GO:0006521=Reactome:REACT_13565, GO:0045471=GO_REF:0000019, GO:0006801=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0009636=PMID:10393963, GO:0044281=Reactome:REACT_111217, GO:0043086=GO_REF:0000019, GO:0007271=PMID:9579781, GO:0006809=PMID:9579781, GO:0005829=Reactome:REACT_13453, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000052, GO:0043525=GO_REF:0000019, GO:0003955=GO_REF:0000003, GO:0043025=GO_REF:0000019, GO:0006979=GO_REF:0000019, GO:0032355=GO_REF:0000019, GO:0004784=GO_REF:0000019} P15559 "NAD(P)H dehydrogenase ""quinone"" 1" protein 20080205 {GO:0005515=IPI, GO:0006805=TAS, GO:0004128=TAS, GO:0007584=IEA, GO:0006521=TAS, GO:0045471=IEA, GO:0006801=IEA, GO:0007568=IEA, GO:0009636=TAS, GO:0044281=TAS, GO:0043086=IEA, GO:0007271=TAS, GO:0006809=TAS, GO:0005829=TAS, GO:0034641=TAS, GO:0005737=IDA, GO:0043525=IEA, GO:0003955=IEA, GO:0043025=IEA, GO:0006979=IEA, GO:0032355=IEA, GO:0004784=IEA} aging, cellular nitrogen compound metabolic process, negative regulation of catalytic activity, nitric oxide biosynthetic process, positive regulation of neuron apoptotic process, regulation of cellular amino acid metabolic process, response to estradiol stimulus, response to ethanol, response to nutrient, response to oxidative stress, response to toxic substance, small molecule metabolic process, superoxide metabolic process, synaptic transmission, cholinergic, xenobiotic metabolic process cytoplasm, cytosol, neuronal cell body NAD(P)H dehydrogenase (quinone) activity, cytochrome-b5 reductase activity, acting on NAD(P)H, protein binding, superoxide dismutase activity Human NQO2 HPA UniProtKB {GO:0001512=GO_REF:0000003, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0009055=PMID:1691923, GO:0005634=GO_REF:0000052, GO:0007613=GO_REF:0000019, GO:0008753=PMID:1691923, GO:0046872=GO_REF:0000037} Q5TD07 "Ribosyldihydronicotinamide dehydrogenase ""quinone""" protein 20100326 {GO:0001512=IEA, GO:0005737=IDA, GO:0005730=IDA, GO:0009055=TAS, GO:0005634=IDA, GO:0007613=IEA, GO:0008753=TAS, GO:0046872=IEA} memory cytoplasm, nucleolus, nucleus NADPH dehydrogenase (quinone) activity, dihydronicotinamide riboside quinone reductase activity, electron carrier activity, metal ion binding Human NR0B1 GOC UniProtKB {GO:0008406=PMID:7990953, GO:0005515=PMID:16713569, GO:0010467=Reactome:REACT_71, GO:0006694=PMID:9384387, GO:0006367=Reactome:REACT_15525, GO:0003700=GO_REF:0000002, GO:0030325=PMID:7990953, GO:0003723=PMID:10848616, GO:0021983=PMID:15464421, GO:0003707=GO_REF:0000002, GO:0033144=PMID:11875111, GO:0035258=PMID:11875111, GO:0005634=PMID:19651776, GO:0007283=GO_REF:0000019, GO:0043433=PMID:19651776, GO:0042803=PMID:16709599, GO:0060008=GO_REF:0000019, GO:0005737=PMID:16709599, GO:0008104=PMID:11875111, GO:0042788=PMID:10848616, GO:0030238=GO_REF:0000019, GO:0004879=PMID:7990953, GO:0003714=PMID:19651776, GO:0019904=PMID:15100213, GO:0006950=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0032448=PMID:9384387, GO:0021854=PMID:15464421, GO:0003677=PMID:7990953, GO:0043565=PMID:9384387, GO:0016020=PMID:10848616, GO:0033327=GO_REF:0000019, GO:0005654=Reactome:REACT_19207, GO:0045596=GO_REF:0000019, GO:0030522=PMID:9384387, GO:0045892=PMID:19651776, GO:0008584=PMID:7990958, GO:0008134=PMID:19651776} P51843 Nuclear receptor subfamily 0 group B member 1 protein 20130413 {GO:0008406=IMP, GO:0005515=IPI, GO:0010467=TAS, GO:0006694=IDA, GO:0006367=TAS, GO:0003700=IEA, GO:0030325=IMP, GO:0003723=IDA, GO:0021983=NAS, GO:0003707=IEA, GO:0033144=IDA, GO:0035258=IPI, GO:0005634=IDA, GO:0007283=IEA, GO:0043433=IMP, GO:0042803=IPI, GO:0060008=IEA, GO:0005737=IDA, GO:0008104=IDA, GO:0042788=IDA, GO:0030238=IEA, GO:0004879=IDA, GO:0003714=IMP, GO:0019904=IPI, GO:0006950=IEA, GO:0000122=IEA, GO:0032448=IDA, GO:0021854=NAS, GO:0003677=IDA, GO:0043565=IDA, GO:0016020=IDA, GO:0033327=IEA, GO:0005654=TAS, GO:0045596=IEA, GO:0030522=NAS, GO:0045892=IMP, GO:0008584=IMP, GO:0008134=IPI} Leydig cell differentiation, Sertoli cell differentiation, adrenal gland development, gene expression, gonad development, hypothalamus development, intracellular receptor signaling pathway, male gonad development, male sex determination, negative regulation of cell differentiation, negative regulation of intracellular steroid hormone receptor signaling pathway, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, pituitary gland development, protein localization, response to stress, spermatogenesis, steroid biosynthetic process, transcription initiation from RNA polymerase II promoter cytoplasm, membrane, nucleoplasm, nucleus, polysomal ribosome DNA binding, DNA hairpin binding, RNA binding, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, protein binding, protein domain specific binding, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity, steroid hormone receptor binding, transcription corepressor activity, transcription factor binding Human NR0B2 Reactome UniProtKB {GO:0005515=PMID:14752053, GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_15525, GO:0003700=GO_REF:0000002, GO:0003714=PMID:14752053, GO:0019904=PMID:17686645, GO:0031100=GO_REF:0000019, GO:0003707=GO_REF:0000002, GO:0005634=PMID:14752053, GO:0000122=GO_REF:0000019, GO:0003677=GO_REF:0000002, GO:0032403=GO_REF:0000019, GO:0042975=GO_REF:0000019, GO:0043433=PMID:14752053, GO:0042803=PMID:16709599, GO:0009749=GO_REF:0000019, GO:0046966=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0046965=GO_REF:0000019, GO:0005737=PMID:14752053, GO:0005654=Reactome:REACT_19207, GO:0032024=GO_REF:0000019, GO:0030521=PMID:19641626, GO:0008203=PMID:11030331} Q15466 Nuclear receptor subfamily 0 group B member 2 protein 20130301 {GO:0005515=IPI, GO:0010467=TAS, GO:0006367=TAS, GO:0003700=IEA, GO:0003714=IDA, GO:0019904=IPI, GO:0031100=IEA, GO:0003707=IEA, GO:0005634=IDA, GO:0000122=IEA, GO:0003677=IEA, GO:0032403=IEA, GO:0042975=IEA, GO:0043433=IDA, GO:0042803=IPI, GO:0009749=IEA, GO:0046966=IEA, GO:0043234=IEA, GO:0046965=IEA, GO:0005737=IDA, GO:0005654=TAS, GO:0032024=IEA, GO:0030521=RCA, GO:0008203=TAS} androgen receptor signaling pathway, cholesterol metabolic process, gene expression, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription from RNA polymerase II promoter, organ regeneration, positive regulation of insulin secretion, response to glucose stimulus, transcription initiation from RNA polymerase II promoter cytoplasm, nucleoplasm, nucleus, protein complex DNA binding, peroxisome proliferator activated receptor binding, protein binding, protein complex binding, protein domain specific binding, protein homodimerization activity, retinoid X receptor binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity, thyroid hormone receptor binding, transcription corepressor activity Human NR1D1 GOC UniProtKB {GO:2000189=PMID:18511497, GO:0034144=PMID:18511497, GO:0010467=Reactome:REACT_71, GO:0000790=PMID:18511497, GO:0006367=Reactome:REACT_15525, GO:0044212=PMID:18511497, GO:0003714=PMID:8622974, GO:0003707=GO_REF:0000002, GO:0005634=PMID:8622974, GO:0010871=PMID:18511497, GO:0000122=PMID:18511497, GO:0043565=GO_REF:0000002, GO:0071222=PMID:18511497, GO:0007623=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_118766, GO:0004879=PMID:8622974, GO:0030522=PMID:8622974} P20393 Nuclear receptor subfamily 1 group D member 1 protein 20130413 {GO:2000189=IDA, GO:0034144=IMP, GO:0010467=TAS, GO:0000790=IDA, GO:0006367=TAS, GO:0044212=IDA, GO:0003714=TAS, GO:0003707=IEA, GO:0005634=TAS, GO:0010871=IMP, GO:0000122=IMP, GO:0043565=IEA, GO:0071222=IMP, GO:0007623=IEA, GO:0008270=IEA, GO:0005654=TAS, GO:0004879=TAS, GO:0030522=TAS} cellular response to lipopolysaccharide, circadian rhythm, gene expression, intracellular receptor signaling pathway, negative regulation of receptor biosynthetic process, negative regulation of toll-like receptor 4 signaling pathway, negative regulation of transcription from RNA polymerase II promoter, positive regulation of cholesterol homeostasis, transcription initiation from RNA polymerase II promoter nuclear chromatin, nucleoplasm, nucleus ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding, steroid hormone receptor activity, transcription corepressor activity, transcription regulatory region DNA binding, zinc ion binding Human NR1D2 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0010467=Reactome:REACT_71, GO:0006355=PMID:7997240, GO:0003700=GO_REF:0000002, GO:0006367=Reactome:REACT_15525, GO:0003707=GO_REF:0000002, GO:0005654=Reactome:REACT_19207, GO:0005634=GO_REF:0000038, GO:0008270=GO_REF:0000002, GO:0004879=PMID:7997240, GO:0030522=PMID:7997240, GO:0006351=GO_REF:0000038} Q6NSM0 Nuclear receptor subfamily 1 group D member 2 protein 20130413 {GO:0043565=IEA, GO:0010467=TAS, GO:0006355=TAS, GO:0003700=IEA, GO:0006367=TAS, GO:0003707=IEA, GO:0005654=TAS, GO:0005634=IEA, GO:0008270=IEA, GO:0004879=TAS, GO:0030522=TAS, GO:0006351=IEA} gene expression, intracellular receptor signaling pathway, regulation of transcription, DNA-dependent, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent nucleoplasm, nucleus ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity, zinc ion binding Human UniProtKB-KW:KW-0804 NR1H2 BHF-UCL UniProtKB {GO:0005515=PMID:19060904, GO:0032376=PMID:16141411, GO:0010467=Reactome:REACT_71, GO:0003700=GO_REF:0000002, GO:0090108=GO_REF:0000019, GO:0006367=Reactome:REACT_15525, GO:0090340=GO_REF:0000019, GO:0001133=GO_REF:0000019, GO:0090187=GO_REF:0000019, GO:0003707=GO_REF:0000002, GO:0005634=PMID:12393874, GO:0010875=PMID:17186944, GO:0046965=GO_REF:0000019, GO:0060336=PMID:21268089, GO:0005737=PMID:12393874, GO:0045944=PMID:16141411, GO:0004879=GO_REF:0000019, GO:0044255=GO_REF:0000019, GO:0042632=GO_REF:0000019, GO:0010867=PMID:17186944, GO:0010745=PMID:17693624, GO:0045723=PMID:17186944, GO:0010884=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0003677=PMID:7926814, GO:0006351=GO_REF:0000038, GO:0010887=PMID:17693624, GO:0045861=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0048384=GO_REF:0000019, GO:0032270=PMID:17186944, GO:0048550=PMID:17693624, GO:0032369=PMID:17693624, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_19207, GO:0045892=PMID:12393874, GO:0051006=PMID:17186944} P55055 Oxysterols receptor LXR-beta protein 20110323 {GO:0005515=IPI, GO:0032376=IDA, GO:0010467=TAS, GO:0003700=IEA, GO:0090108=IEA, GO:0006367=TAS, GO:0090340=IEA, GO:0001133=IEA, GO:0090187=IEA, GO:0003707=IEA, GO:0005634=IDA, GO:0010875=IMP, GO:0046965=IEA, GO:0060336=NAS, GO:0005737=IDA, GO:0045944=IDA, GO:0004879=IEA, GO:0044255=IEA, GO:0042632=IEA, GO:0010867=IMP, GO:0010745=IC, GO:0045723=IMP, GO:0010884=IEA, GO:0000122=IEA, GO:0003677=TAS, GO:0006351=IEA, GO:0010887=IMP, GO:0045861=IEA, GO:0043565=IEA, GO:0048384=IEA, GO:0032270=IMP, GO:0048550=IMP, GO:0032369=IMP, GO:0008270=IEA, GO:0005654=TAS, GO:0045892=IDA, GO:0051006=IMP} cellular lipid metabolic process, cholesterol homeostasis, gene expression, negative regulation of cholesterol storage, negative regulation of interferon-gamma-mediated signaling pathway, negative regulation of lipid transport, negative regulation of macrophage derived foam cell differentiation, negative regulation of pinocytosis, negative regulation of proteolysis, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of cellular protein metabolic process, positive regulation of cholesterol efflux, positive regulation of cholesterol transport, positive regulation of fatty acid biosynthetic process, positive regulation of high-density lipoprotein particle assembly, positive regulation of lipid storage, positive regulation of lipoprotein lipase activity, positive regulation of pancreatic juice secretion, positive regulation of secretion of lysosomal enzymes, positive regulation of transcription from RNA polymerase II promoter, positive regulation of triglyceride biosynthetic process, retinoic acid receptor signaling pathway, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, nucleoplasm, nucleus DNA binding, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, protein binding, retinoid X receptor binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, sequence-specific transcription regulatory region DNA binding RNA polymerase II transcription factor recruiting transcription factor activity, steroid hormone receptor activity, zinc ion binding Human NR1H3 BHF-UCL UniProtKB {GO:0034145=PMID:18511497, GO:0005515=PMID:12040021, GO:2000189=PMID:18511497, GO:0032376=PMID:16141411, GO:0010467=Reactome:REACT_71, GO:0000790=PMID:18511497, GO:0006367=Reactome:REACT_15525, GO:0003700=GO_REF:0000002, GO:0044212=PMID:18511497, GO:0090341=GO_REF:0000024, GO:0032810=PMID:19628791, GO:0043031=GO_REF:0000024, GO:0003707=GO_REF:0000002, GO:0090188=GO_REF:0000024, GO:0070328=GO_REF:0000024, GO:0005634=PMID:7744246, GO:0010870=PMID:18511497, GO:0010875=PMID:16141411, GO:0060336=PMID:21268089, GO:0015485=PMID:11090131, GO:0045944=PMID:18511497, GO:0004879=GO_REF:0000019, GO:0044255=GO_REF:0000019, GO:0042632=GO_REF:0000024, GO:0010867=PMID:17693624, GO:0010745=PMID:17693624, GO:0045723=PMID:17186944, GO:0003713=PMID:7744246, GO:0055088=GO_REF:0000024, GO:0043277=PMID:19628791, GO:0000122=GO_REF:0000024, GO:0003677=PMID:7744246, GO:0006351=GO_REF:0000038, GO:0010887=PMID:17693624, GO:0045861=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0032270=PMID:17186944, GO:0071222=PMID:18511497, GO:0050728=GO_REF:0000024, GO:0048550=PMID:17693624, GO:0055092=GO_REF:0000024, GO:0032570=PMID:16141411, GO:0032369=PMID:17693624, GO:0042752=PMID:18511497, GO:0005654=Reactome:REACT_19207, GO:0008270=GO_REF:0000002, GO:0045893=PMID:19628791, GO:0051006=PMID:17186944} Q13133 Oxysterols receptor LXR-alpha protein 20110117 {GO:0034145=IDA, GO:0005515=IPI, GO:2000189=IDA, GO:0032376=IDA, GO:0010467=TAS, GO:0000790=IDA, GO:0006367=TAS, GO:0003700=IEA, GO:0044212=IDA, GO:0090341=ISS, GO:0032810=IDA, GO:0043031=ISS, GO:0003707=IEA, GO:0090188=ISS, GO:0070328=ISS, GO:0005634=TAS, GO:0010870=IDA, GO:0010875=IDA, GO:0060336=NAS, GO:0015485=TAS, GO:0045944=IDA, GO:0004879=IEA, GO:0044255=IEA, GO:0042632=ISS, GO:0010867=IMP, GO:0010745=IC, GO:0045723=IMP, GO:0003713=TAS, GO:0055088=ISS, GO:0043277=IMP, GO:0000122=ISS, GO:0003677=TAS, GO:0006351=IEA, GO:0010887=IMP, GO:0045861=IEA, GO:0043565=IEA, GO:0032270=IMP, GO:0071222=IDA, GO:0050728=ISS, GO:0048550=IMP, GO:0055092=ISS, GO:0032570=IDA, GO:0032369=IMP, GO:0042752=TAS, GO:0005654=TAS, GO:0008270=IEA, GO:0045893=IMP, GO:0051006=IMP} apoptotic cell clearance, cellular lipid metabolic process, cellular response to lipopolysaccharide, cholesterol homeostasis, gene expression, lipid homeostasis, negative regulation of cholesterol storage, negative regulation of inflammatory response, negative regulation of interferon-gamma-mediated signaling pathway, negative regulation of lipid transport, negative regulation of macrophage activation, negative regulation of macrophage derived foam cell differentiation, negative regulation of pancreatic juice secretion, negative regulation of pinocytosis, negative regulation of proteolysis, negative regulation of secretion of lysosomal enzymes, negative regulation of transcription from RNA polymerase II promoter, positive regulation of cellular protein metabolic process, positive regulation of cholesterol efflux, positive regulation of cholesterol homeostasis, positive regulation of cholesterol transport, positive regulation of fatty acid biosynthetic process, positive regulation of lipoprotein lipase activity, positive regulation of receptor biosynthetic process, positive regulation of toll-like receptor 4 signaling pathway, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of triglyceride biosynthetic process, regulation of circadian rhythm, response to progesterone stimulus, sterol homeostasis, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, triglyceride homeostasis nuclear chromatin, nucleoplasm, nucleus DNA binding, cholesterol binding, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity, sterol response element binding, transcription coactivator activity, transcription regulatory region DNA binding, zinc ion binding Human NR1H4 BHF-UCL UniProtKB {GO:0005515=PMID:14701856, GO:0090181=PMID:21757002, GO:0010467=Reactome:REACT_71, GO:0032052=PMID:21757002, GO:0003700=PMID:9223286, GO:0006367=Reactome:REACT_15525, GO:0001190=PMID:21757002, GO:0003705=PMID:21757002, GO:0003707=GO_REF:0000019, GO:0005634=GO_REF:0000038, GO:0071417=PMID:21757002, GO:0046965=GO_REF:0000019, GO:2000213=PMID:21757002, GO:0070857=PMID:21757002, GO:0045944=PMID:21757002, GO:0001080=PMID:21757002, GO:0032496=GO_REF:0000019, GO:0008206=GO_REF:0000019, GO:0004879=PMID:21757002, GO:0016922=PMID:21757002, GO:0042277=GO_REF:0000019, GO:0005719=PMID:21757002, GO:0003714=PMID:10334992, GO:0003713=PMID:10334992, GO:0006109=GO_REF:0000019, GO:0048565=GO_REF:0000019, GO:0000122=PMID:21757002, GO:0006351=GO_REF:0000038, GO:0009749=GO_REF:0000019, GO:0043565=PMID:12815072, GO:0007165=PMID:10334993, GO:2001250=GO_REF:0000019, GO:0071229=PMID:21757002, GO:0005654=Reactome:REACT_19207, GO:0000980=PMID:21757002, GO:0008270=GO_REF:0000002, GO:0004887=GO_REF:0000002, GO:0030522=GO_REF:0000024, GO:0034255=PMID:21757002} Q96RI1 Bile acid receptor protein 20111201 {GO:0005515=IPI, GO:0090181=TAS, GO:0010467=TAS, GO:0032052=TAS, GO:0003700=TAS, GO:0006367=TAS, GO:0001190=IDA, GO:0003705=IDA, GO:0003707=IEA, GO:0005634=IEA, GO:0071417=ISS, GO:0046965=IEA, GO:2000213=ISS, GO:0070857=TAS, GO:0045944=IMP, GO:0001080=IC, GO:0032496=IEA, GO:0008206=IEA, GO:0004879=ISS, GO:0016922=TAS, GO:0042277=IEA, GO:0005719=IDA, GO:0003714=TAS, GO:0003713=TAS, GO:0006109=IEA, GO:0048565=IEA, GO:0000122=ISS, GO:0006351=IEA, GO:0009749=IEA, GO:0043565=IDA, GO:0007165=TAS, GO:2001250=IEA, GO:0071229=IDA, GO:0005654=TAS, GO:0000980=IDA, GO:0008270=IEA, GO:0004887=IEA, GO:0030522=ISS, GO:0034255=ISS} bile acid metabolic process, cellular response to acid, cellular response to organic nitrogen, digestive tract development, gene expression, intracellular receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, nitrogen catabolite activation of transcription from RNA polymerase II promoter, positive regulation of ammonia assimilation cycle, positive regulation of glutamate metabolic process, positive regulation of transcription from RNA polymerase II promoter, regulation of bile acid biosynthetic process, regulation of carbohydrate metabolic process, regulation of cholesterol metabolic process, regulation of urea metabolic process, response to glucose stimulus, response to lipopolysaccharide, signal transduction, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent nuclear euchromatin, nucleoplasm, nucleus RNA polymerase II distal enhancer sequence-specific DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription, bile acid binding, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, ligand-dependent nuclear receptor binding, peptide binding, protein binding, retinoid X receptor binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity, thyroid hormone receptor activity, transcription coactivator activity, transcription corepressor activity, zinc ion binding Human NR1I2 GOC UniProtKB {GO:0005515=PMID:22939624, GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_15525, GO:0006805=PMID:12578355, GO:0003700=GO_REF:0000002, GO:0003713=PMID:9727070, GO:0003707=GO_REF:0000002, GO:0046618=PMID:12578355, GO:0005634=GO_REF:0000038, GO:0042908=PMID:12578355, GO:0006351=GO_REF:0000038, GO:0043565=GO_REF:0000002, GO:0010628=GO_REF:0000019, GO:0007165=PMID:9784494, GO:0042738=PMID:12578355, GO:0008144=PMID:12578355, GO:0005654=Reactome:REACT_19207, GO:0008270=GO_REF:0000002, GO:0004879=PMID:12578355, GO:0004887=GO_REF:0000002, GO:0045893=PMID:12578355, GO:0030522=PMID:12578355, GO:0045892=PMID:11891224, GO:0008202=PMID:9784494} O75469 Nuclear receptor subfamily 1 group I member 2 protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0006367=TAS, GO:0006805=IDA, GO:0003700=IEA, GO:0003713=TAS, GO:0003707=IEA, GO:0046618=IDA, GO:0005634=IEA, GO:0042908=IDA, GO:0006351=IEA, GO:0043565=IEA, GO:0010628=IEA, GO:0007165=TAS, GO:0042738=IDA, GO:0008144=IDA, GO:0005654=TAS, GO:0008270=IEA, GO:0004879=IDA, GO:0004887=IEA, GO:0045893=IDA, GO:0030522=IDA, GO:0045892=IDA, GO:0008202=TAS} drug export, exogenous drug catabolic process, gene expression, intracellular receptor signaling pathway, negative regulation of transcription, DNA-dependent, positive regulation of gene expression, positive regulation of transcription, DNA-dependent, signal transduction, steroid metabolic process, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, xenobiotic metabolic process, xenobiotic transport nucleoplasm, nucleus drug binding, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity, thyroid hormone receptor activity, transcription coactivator activity, zinc ion binding Human NR1I3 UniProtKB UniProtKB {GO:0010467=Reactome:REACT_71, GO:0004882=PMID:9783588, GO:0006367=Reactome:REACT_15525, GO:0003700=GO_REF:0000002, GO:0003713=PMID:9783588, GO:0003707=GO_REF:0000002, GO:0005634=GO_REF:0000038, GO:0003677=PMID:9783588, GO:0006351=GO_REF:0000038, GO:0046872=GO_REF:0000038, GO:0043565=GO_REF:0000002, GO:0007165=PMID:9783588, GO:0005737=GO_REF:0000024, GO:0005654=Reactome:REACT_19207, GO:0008270=GO_REF:0000002, GO:0004879=PMID:8114692, GO:0004887=GO_REF:0000002, GO:0005856=GO_REF:0000039, GO:0030522=PMID:8114692, GO:0030521=PMID:9783588} Q6GZ81 Constitutive androstane receptor SV9 protein 20130413 {GO:0010467=TAS, GO:0004882=TAS, GO:0006367=TAS, GO:0003700=IEA, GO:0003713=TAS, GO:0003707=IEA, GO:0005634=IEA, GO:0003677=TAS, GO:0006351=IEA, GO:0046872=IEA, GO:0043565=IEA, GO:0007165=TAS, GO:0005737=ISS, GO:0005654=TAS, GO:0008270=IEA, GO:0004879=TAS, GO:0004887=IEA, GO:0005856=IEA, GO:0030522=TAS, GO:0030521=TAS} androgen receptor signaling pathway, gene expression, intracellular receptor signaling pathway, signal transduction, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, cytoskeleton, nucleoplasm, nucleus DNA binding, androgen receptor activity, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, metal ion binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity, thyroid hormone receptor activity, transcription coactivator activity, zinc ion binding Human UniProtKB-KW:KW-0804 NR2C1 Reactome UniProtKB {GO:0005515=PMID:12093804, GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_15525, GO:0003700=GO_REF:0000002, GO:0042826=GO_REF:0000019, GO:0003707=GO_REF:0000002, GO:0000122=GO_REF:0000019, GO:0003677=PMID:3421977, GO:0042803=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0048386=GO_REF:0000019, GO:0016605=GO_REF:0000039, GO:0005654=Reactome:REACT_19207, GO:0008270=GO_REF:0000002, GO:0004872=PMID:3421977} P13056 Nuclear receptor subfamily 2 group C member 1 protein 20130301 {GO:0005515=IPI, GO:0010467=TAS, GO:0006367=TAS, GO:0003700=IEA, GO:0042826=IEA, GO:0003707=IEA, GO:0000122=IEA, GO:0003677=TAS, GO:0042803=IEA, GO:0043565=IEA, GO:0048386=IEA, GO:0016605=IEA, GO:0005654=TAS, GO:0008270=IEA, GO:0004872=TAS} gene expression, negative regulation of transcription from RNA polymerase II promoter, positive regulation of retinoic acid receptor signaling pathway, transcription initiation from RNA polymerase II promoter PML body, nucleoplasm DNA binding, histone deacetylase binding, protein binding, protein homodimerization activity, receptor activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity, zinc ion binding Human NR2C2 HPA UniProtKB {GO:0005515=PMID:16887930, GO:0010467=Reactome:REACT_71, GO:0006355=PMID:9006963, GO:0051321=GO_REF:0000019, GO:0006367=Reactome:REACT_15525, GO:0003700=PMID:10644740, GO:0046982=PMID:17974920, GO:0003713=PMID:9006963, GO:0005730=GO_REF:0000052, GO:0003707=GO_REF:0000002, GO:0021549=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0007283=GO_REF:0000019, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000038, GO:0030154=GO_REF:0000037, GO:0007399=PMID:9006963, GO:0043565=PMID:10644740, GO:0045944=PMID:10644740, GO:0048520=GO_REF:0000019, GO:0040019=GO_REF:0000019, GO:0005654=Reactome:REACT_19207, GO:0004872=PMID:9006963, GO:0008270=GO_REF:0000002} P49116 Nuclear receptor subfamily 2 group C member 2 protein 20080205 {GO:0005515=IPI, GO:0010467=TAS, GO:0006355=TAS, GO:0051321=IEA, GO:0006367=TAS, GO:0003700=IDA, GO:0046982=IDA, GO:0003713=TAS, GO:0005730=IDA, GO:0003707=IEA, GO:0021549=IEA, GO:0005634=IDA, GO:0007283=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0030154=IEA, GO:0007399=TAS, GO:0043565=IDA, GO:0045944=IDA, GO:0048520=IEA, GO:0040019=IEA, GO:0005654=TAS, GO:0004872=TAS, GO:0008270=IEA} cell differentiation, cerebellum development, gene expression, meiotic cell cycle, nervous system development, positive regulation of behavior, positive regulation of embryonic development, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, spermatogenesis, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent nucleolus, nucleoplasm, nucleus DNA binding, protein binding, protein heterodimerization activity, receptor activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity, transcription coactivator activity, zinc ion binding NOT Human NR2C2AP Reactome UniProtKB {GO:0005515=PMID:22486638, GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_15525, GO:0005654=Reactome:REACT_19207, GO:0007155=GO_REF:0000002} Q86WQ0 Nuclear receptor 2C2-associated protein protein 20130301 {GO:0005515=IPI, GO:0010467=TAS, GO:0006367=TAS, GO:0005654=TAS, GO:0007155=IEA} cell adhesion, gene expression, transcription initiation from RNA polymerase II promoter nucleoplasm protein binding Human NR2E1 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0021960=GO_REF:0000019, GO:0006367=Reactome:REACT_15525, GO:0003700=GO_REF:0000002, GO:0060041=GO_REF:0000019, GO:0008347=GO_REF:0000019, GO:0042826=GO_REF:0000019, GO:0003707=GO_REF:0000002, GO:0060291=GO_REF:0000019, GO:0005634=GO_REF:0000038, GO:0021772=GO_REF:0000019, GO:0030198=GO_REF:0000019, GO:0002118=GO_REF:0000019, GO:0001662=GO_REF:0000019, GO:0035019=GO_REF:0000019, GO:0060164=GO_REF:0000019, GO:0021895=GO_REF:0000019, GO:0021542=GO_REF:0000019, GO:2000179=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:2000178=GO_REF:0000019, GO:2000648=GO_REF:0000019, GO:0021872=GO_REF:0000019, GO:0021819=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0045787=GO_REF:0000019, GO:0006351=GO_REF:0000038, GO:0045766=GO_REF:0000019, GO:0007399=PMID:9628820, GO:0043565=GO_REF:0000002, GO:0048814=GO_REF:0000019, GO:0048712=GO_REF:0000019, GO:0090049=GO_REF:0000019, GO:0001078=GO_REF:0000019, GO:0001077=GO_REF:0000019, GO:0021764=GO_REF:0000019, GO:0045165=GO_REF:0000019, GO:0045665=GO_REF:0000019, GO:0035176=GO_REF:0000019, GO:0005654=Reactome:REACT_19207, GO:0008270=GO_REF:0000002, GO:0007601=GO_REF:0000019} Q9Y466 Nuclear receptor subfamily 2 group E member 1 protein 20130301 {GO:0010467=TAS, GO:0021960=IEA, GO:0006367=TAS, GO:0003700=IEA, GO:0060041=IEA, GO:0008347=IEA, GO:0042826=IEA, GO:0003707=IEA, GO:0060291=IEA, GO:0005634=IEA, GO:0021772=IEA, GO:0030198=IEA, GO:0002118=IEA, GO:0001662=IEA, GO:0035019=IEA, GO:0060164=IEA, GO:0021895=IEA, GO:0021542=IEA, GO:2000179=IEA, GO:0043066=IEA, GO:2000178=IEA, GO:2000648=IEA, GO:0021872=IEA, GO:0021819=IEA, GO:0003677=IEA, GO:0045787=IEA, GO:0006351=IEA, GO:0045766=IEA, GO:0007399=TAS, GO:0043565=IEA, GO:0048814=IEA, GO:0048712=IEA, GO:0090049=IEA, GO:0001078=IEA, GO:0001077=IEA, GO:0021764=IEA, GO:0045165=IEA, GO:0045665=IEA, GO:0035176=IEA, GO:0005654=TAS, GO:0008270=IEA, GO:0007601=IEA} aggressive behavior, amygdala development, anterior commissure morphogenesis, behavioral fear response, cell fate commitment, cerebral cortex neuron differentiation, dentate gyrus development, extracellular matrix organization, forebrain generation of neurons, gene expression, glial cell migration, layer formation in cerebral cortex, long-term synaptic potentiation, negative regulation of apoptotic process, negative regulation of astrocyte differentiation, negative regulation of neural precursor cell proliferation, negative regulation of neuron differentiation, nervous system development, olfactory bulb development, positive regulation of angiogenesis, positive regulation of cell cycle, positive regulation of neural precursor cell proliferation, positive regulation of stem cell proliferation, regulation of cell migration involved in sprouting angiogenesis, regulation of dendrite morphogenesis, regulation of timing of neuron differentiation, retina development in camera-type eye, social behavior, somatic stem cell maintenance, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, visual perception nucleoplasm, nucleus DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, histone deacetylase binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity, zinc ion binding Human NR2E3 GOC UniProtKB {GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_15525, GO:0006366=PMID:10220376, GO:0003707=GO_REF:0000002, GO:0005634=PMID:10220376, GO:0043565=GO_REF:0000002, GO:0007165=PMID:10220376, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_19207, GO:0004879=PMID:10220376, GO:0007602=PMID:10220376, GO:0007601=GO_REF:0000037, GO:0030522=PMID:10220376} Q9Y5X4 Photoreceptor-specific nuclear receptor protein 20130413 {GO:0010467=TAS, GO:0006367=TAS, GO:0006366=TAS, GO:0003707=IEA, GO:0005634=TAS, GO:0043565=IEA, GO:0007165=TAS, GO:0008270=IEA, GO:0005654=TAS, GO:0004879=TAS, GO:0007602=TAS, GO:0007601=IEA, GO:0030522=TAS} gene expression, intracellular receptor signaling pathway, phototransduction, signal transduction, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, visual perception nucleoplasm, nucleus ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding, steroid hormone receptor activity, zinc ion binding Human NR2F1 GOC UniProtKB {GO:0005515=PMID:11043578, GO:0010467=Reactome:REACT_71, GO:0003700=PMID:10644740, GO:0006367=Reactome:REACT_15525, GO:0003713=PMID:2739739, GO:0003707=GO_REF:0000002, GO:0005634=PMID:10644740, GO:0000122=PMID:10644740, GO:0043565=PMID:10644740, GO:0007165=PMID:2739739, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_19207, GO:0004879=GO_REF:0000002, GO:0030900=GO_REF:0000019, GO:0001764=GO_REF:0000019, GO:0030522=PMID:8530078} P10589 COUP transcription factor 1 protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0003700=IDA, GO:0006367=TAS, GO:0003713=TAS, GO:0003707=IEA, GO:0005634=IDA, GO:0000122=IDA, GO:0043565=IDA, GO:0007165=TAS, GO:0008270=IEA, GO:0005654=TAS, GO:0004879=IEA, GO:0030900=IEA, GO:0001764=IEA, GO:0030522=TAS} forebrain development, gene expression, intracellular receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, neuron migration, signal transduction, transcription initiation from RNA polymerase II promoter nucleoplasm, nucleus ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity, transcription coactivator activity, zinc ion binding Human NR2F2 GOC UniProtKB {GO:0006629=PMID:1899293, GO:0005515=PMID:19210544, GO:0060674=GO_REF:0000019, GO:0003700=PMID:19210544, GO:0045736=PMID:19210544, GO:0009956=GO_REF:0000019, GO:0003707=GO_REF:0000002, GO:0048514=GO_REF:0000019, GO:0005634=PMID:19210544, GO:0009952=GO_REF:0000019, GO:0042803=PMID:18798693, GO:0004879=PMID:18798693, GO:0032355=GO_REF:0000019, GO:0001945=GO_REF:0000019, GO:0006357=PMID:1899293, GO:0003714=PMID:1899293, GO:0060707=GO_REF:0000019, GO:0001893=GO_REF:0000019, GO:0000122=PMID:9343308, GO:0009566=GO_REF:0000019, GO:0043565=PMID:9343308, GO:0010596=PMID:19210544, GO:0007165=PMID:1899293, GO:0060849=PMID:18815287, GO:0001937=PMID:19210544, GO:0007519=GO_REF:0000019, GO:0001972=PMID:18798693, GO:0060173=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0030900=GO_REF:0000019, GO:0001764=GO_REF:0000019, GO:0045893=PMID:18815287, GO:0030522=PMID:1899293, GO:0045892=PMID:19210544} P24468 COUP transcription factor 2 protein 20130413 {GO:0006629=TAS, GO:0005515=IPI, GO:0060674=IEA, GO:0003700=IC, GO:0045736=IDA, GO:0009956=IEA, GO:0003707=IEA, GO:0048514=IEA, GO:0005634=IDA, GO:0009952=IEA, GO:0042803=IPI, GO:0004879=IDA, GO:0032355=IEA, GO:0001945=IEA, GO:0006357=TAS, GO:0003714=TAS, GO:0060707=IEA, GO:0001893=IEA, GO:0000122=IDA, GO:0009566=IEA, GO:0043565=IDA, GO:0010596=IMP, GO:0007165=TAS, GO:0060849=IMP, GO:0001937=IMP, GO:0007519=IEA, GO:0001972=IDA, GO:0060173=IEA, GO:0008270=IEA, GO:0030900=IEA, GO:0001764=IEA, GO:0045893=IMP, GO:0030522=TAS, GO:0045892=IDA} anterior/posterior pattern specification, blood vessel morphogenesis, fertilization, forebrain development, intracellular receptor signaling pathway, limb development, lipid metabolic process, lymph vessel development, maternal placenta development, negative regulation of cyclin-dependent protein serine/threonine kinase activity, negative regulation of endothelial cell migration, negative regulation of endothelial cell proliferation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, neuron migration, placenta blood vessel development, positive regulation of transcription, DNA-dependent, radial pattern formation, regulation of transcription from RNA polymerase II promoter, regulation of transcription involved in lymphatic endothelial cell fate commitment, response to estradiol stimulus, signal transduction, skeletal muscle tissue development, trophoblast giant cell differentiation nucleus ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, protein binding, protein homodimerization activity, retinoic acid binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity, transcription corepressor activity, zinc ion binding Human NR2F6 GOC UniProtKB {GO:0005515=PMID:20195357, GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_15525, GO:0003700=PMID:10644740, GO:0003707=GO_REF:0000002, GO:0005634=PMID:10644740, GO:0000122=PMID:10644740, GO:0003677=PMID:2905047, GO:0043565=PMID:10644740, GO:0007165=PMID:2905047, GO:0048666=GO_REF:0000019, GO:0005654=Reactome:REACT_19207, GO:0008270=GO_REF:0000002, GO:0004879=PMID:2905047, GO:0004887=PMID:2905047, GO:0030522=PMID:2905047, GO:0043153=GO_REF:0000019, GO:0050965=GO_REF:0000019} P10588 Nuclear receptor subfamily 2 group F member 6 protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0006367=TAS, GO:0003700=IDA, GO:0003707=IEA, GO:0005634=IDA, GO:0000122=IDA, GO:0003677=TAS, GO:0043565=IDA, GO:0007165=TAS, GO:0048666=IEA, GO:0005654=TAS, GO:0008270=IEA, GO:0004879=TAS, GO:0004887=TAS, GO:0030522=TAS, GO:0043153=IEA, GO:0050965=IEA} detection of temperature stimulus involved in sensory perception of pain, entrainment of circadian clock by photoperiod, gene expression, intracellular receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, neuron development, signal transduction, transcription initiation from RNA polymerase II promoter nucleoplasm, nucleus DNA binding, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity, thyroid hormone receptor activity, zinc ion binding Human NR3C1 HPA UniProtKB {GO:0005515=PMID:12552091, GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_15525, GO:0004883=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0030325=GO_REF:0000019, GO:0006366=PMID:8621628, GO:0003707=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0005829=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0043525=GO_REF:0000019, GO:0005759=PMID:10887960, GO:0046983=GO_REF:0000019, GO:0005496=GO_REF:0000002, GO:0060603=GO_REF:0000019, GO:0006355=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0006351=PMID:10887960, GO:0006111=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0007165=PMID:7769088, GO:0016020=GO_REF:0000019, GO:0005654=Reactome:REACT_19207, GO:0008270=GO_REF:0000002, GO:0008211=GO_REF:0000019, GO:0031946=GO_REF:0000019, GO:0016568=GO_REF:0000037} Q3MSN4 Nuclear receptor subfamily 3, group C, member 1 (Glucocorticoid receptor) protein 20080818 {GO:0005515=IPI, GO:0010467=TAS, GO:0006367=TAS, GO:0004883=IEA, GO:0003700=IEA, GO:0030325=IEA, GO:0006366=TAS, GO:0003707=IEA, GO:0005634=IDA, GO:0005829=IEA, GO:0005737=IDA, GO:0043525=IEA, GO:0005759=TAS, GO:0046983=IEA, GO:0005496=IEA, GO:0060603=IEA, GO:0006355=IEA, GO:0005730=IDA, GO:0006351=TAS, GO:0006111=IEA, GO:0043565=IEA, GO:0007165=TAS, GO:0016020=IEA, GO:0005654=TAS, GO:0008270=IEA, GO:0008211=IEA, GO:0031946=IEA, GO:0016568=IEA} adrenal gland development, chromatin modification, gene expression, glucocorticoid metabolic process, mammary gland duct morphogenesis, positive regulation of neuron apoptotic process, regulation of glucocorticoid biosynthetic process, regulation of gluconeogenesis, regulation of transcription, DNA-dependent, signal transduction, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, cytosol, membrane, mitochondrial matrix, nucleolus, nucleoplasm, nucleus glucocorticoid receptor activity, protein binding, protein dimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid binding, steroid hormone receptor activity, zinc ion binding Human NR3C2 Reactome UniProtKB {GO:0005515=PMID:11518808, GO:0010467=Reactome:REACT_71, GO:0007588=GO_REF:0000019, GO:0006367=Reactome:REACT_15525, GO:0003700=GO_REF:0000002, GO:0003707=GO_REF:0000002, GO:0006883=GO_REF:0000019, GO:0005634=GO_REF:0000038, GO:0006351=GO_REF:0000038, GO:0043565=GO_REF:0000002, GO:0007165=PMID:3037703, GO:0005789=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_19207, GO:0005496=GO_REF:0000019} P08235 Mineralocorticoid receptor protein 20130301 {GO:0005515=IPI, GO:0010467=TAS, GO:0007588=IEA, GO:0006367=TAS, GO:0003700=IEA, GO:0003707=IEA, GO:0006883=IEA, GO:0005634=IEA, GO:0006351=IEA, GO:0043565=IEA, GO:0007165=TAS, GO:0005789=IEA, GO:0008270=IEA, GO:0005654=TAS, GO:0005496=IEA} cellular sodium ion homeostasis, excretion, gene expression, signal transduction, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent endoplasmic reticulum membrane, nucleoplasm, nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid binding, steroid hormone receptor activity, zinc ion binding Human NR4A1 UniProtKB UniProtKB {GO:0005515=PMID:21988832, GO:0010467=Reactome:REACT_71, GO:0005667=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0006367=Reactome:REACT_15525, GO:0046982=GO_REF:0000019, GO:0048015=Reactome:REACT_12464, GO:0071310=GO_REF:0000019, GO:0003707=GO_REF:0000002, GO:0005634=GO_REF:0000038, GO:0006917=GO_REF:0000019, GO:0003677=GO_REF:0000024, GO:0042803=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0007165=PMID:2626032, GO:0001077=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0005654=Reactome:REACT_147721, GO:0008270=GO_REF:0000002, GO:0004879=GO_REF:0000002, GO:0043154=GO_REF:0000019, GO:0030522=PMID:2626032} Q15627 Nuclear receptor subfamily 4 group A member 1 protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0005667=IEA, GO:0048011=TAS, GO:0006367=TAS, GO:0046982=IEA, GO:0048015=TAS, GO:0071310=IEA, GO:0003707=IEA, GO:0005634=IEA, GO:0006917=IEA, GO:0003677=ISS, GO:0042803=IEA, GO:0043565=IEA, GO:0007165=TAS, GO:0001077=IEA, GO:0007173=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0005654=TAS, GO:0008270=IEA, GO:0004879=IEA, GO:0043154=IEA, GO:0030522=TAS} cellular response to organic substance, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, gene expression, induction of apoptosis, innate immune response, intracellular receptor signaling pathway, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, signal transduction, transcription initiation from RNA polymerase II promoter nucleoplasm, nucleus, transcription factor complex DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, protein binding, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding, steroid hormone receptor activity, zinc ion binding Human UniProtKB-KW:KW-0539 NR4A2 ENSEMBL UniProtKB {GO:0005515=PMID:20195357, GO:0010467=Reactome:REACT_71, GO:0008344=GO_REF:0000019, GO:0021986=GO_REF:0000019, GO:0006367=Reactome:REACT_15525, GO:0016265=GO_REF:0000019, GO:0003707=GO_REF:0000002, GO:0005634=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0042053=GO_REF:0000019, GO:0042416=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0043524=GO_REF:0000019, GO:0043576=GO_REF:0000019, GO:0010035=GO_REF:0000019, GO:0031668=PMID:7877627, GO:0045944=GO_REF:0000019, GO:0004879=GO_REF:0000002, GO:0001666=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0042551=GO_REF:0000019, GO:0021952=GO_REF:0000019, GO:0033554=GO_REF:0000019, GO:0043085=GO_REF:0000019, GO:0006351=PMID:17184956, GO:0043565=GO_REF:0000019, GO:0007165=PMID:7877627, GO:0001975=GO_REF:0000019, GO:0071542=GO_REF:0000019, GO:0005654=Reactome:REACT_19207, GO:0008270=GO_REF:0000002, GO:0017085=GO_REF:0000019, GO:0001764=GO_REF:0000019, GO:0030522=PMID:7877627} Q6NXU0 cDNA FLJ75035, highly similar to Homo sapiens nuclear receptor subfamily 4, group A, member 2 (NR4A2), transcript variant 4, mRNA protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0008344=IEA, GO:0021986=IEA, GO:0006367=TAS, GO:0016265=IEA, GO:0003707=IEA, GO:0005634=IEA, GO:0009791=IEA, GO:0042053=IEA, GO:0042416=IEA, GO:0005737=IEA, GO:0043524=IEA, GO:0043576=IEA, GO:0010035=IEA, GO:0031668=IDA, GO:0045944=IEA, GO:0004879=IEA, GO:0001666=IEA, GO:0046982=IEA, GO:0042551=IEA, GO:0021952=IEA, GO:0033554=IEA, GO:0043085=IEA, GO:0006351=IDA, GO:0043565=IEA, GO:0007165=NAS, GO:0001975=IEA, GO:0071542=IEA, GO:0005654=TAS, GO:0008270=IEA, GO:0017085=IEA, GO:0001764=IEA, GO:0030522=TAS} adult locomotory behavior, cellular response to extracellular stimulus, cellular response to stress, central nervous system projection neuron axonogenesis, death, dopamine biosynthetic process, dopaminergic neuron differentiation, gene expression, habenula development, intracellular receptor signaling pathway, negative regulation of neuron apoptotic process, neuron maturation, neuron migration, positive regulation of catalytic activity, positive regulation of transcription from RNA polymerase II promoter, post-embryonic development, regulation of dopamine metabolic process, regulation of respiratory gaseous exchange, response to amphetamine, response to hypoxia, response to inorganic substance, response to insecticide, signal transduction, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, nucleoplasm, nucleus ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, protein binding, protein heterodimerization activity, sequence-specific DNA binding, steroid hormone receptor activity, zinc ion binding Human Ensembl:ENSMUSP00000028166 NR4A3 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_15525, GO:0031100=GO_REF:0000019, GO:0003707=GO_REF:0000002, GO:0043434=GO_REF:0000019, GO:0005634=PMID:8634690, GO:0048752=GO_REF:0000019, GO:0043524=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0060005=GO_REF:0000019, GO:0050885=GO_REF:0000019, GO:0030534=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0001707=GO_REF:0000019, GO:0033554=GO_REF:0000019, GO:0045787=GO_REF:0000019, GO:0003677=PMID:8634690, GO:0043565=GO_REF:0000019, GO:0021766=GO_REF:0000019, GO:0008150=GO_REF:0000015, GO:0001077=GO_REF:0000019, GO:2000108=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_19207, GO:0004887=PMID:8570200} Q92570 Nuclear receptor subfamily 4 group A member 3 protein 20130301 {GO:0010467=TAS, GO:0006367=TAS, GO:0031100=IEA, GO:0003707=IEA, GO:0043434=IEA, GO:0005634=NAS, GO:0048752=IEA, GO:0043524=IEA, GO:0007411=IEA, GO:0060005=IEA, GO:0050885=IEA, GO:0030534=IEA, GO:0005667=IEA, GO:0001707=IEA, GO:0033554=IEA, GO:0045787=IEA, GO:0003677=NAS, GO:0043565=IEA, GO:0021766=IEA, GO:0008150=ND, GO:0001077=IEA, GO:2000108=IEA, GO:0008270=IEA, GO:0005654=TAS, GO:0004887=TAS} adult behavior, axon guidance, biological_process, cellular response to stress, gene expression, hippocampus development, mesoderm formation, negative regulation of neuron apoptotic process, neuromuscular process controlling balance, organ regeneration, positive regulation of cell cycle, positive regulation of leukocyte apoptotic process, response to peptide hormone stimulus, semicircular canal morphogenesis, transcription initiation from RNA polymerase II promoter, vestibular reflex nucleoplasm, nucleus, transcription factor complex DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, sequence-specific DNA binding, steroid hormone receptor activity, thyroid hormone receptor activity, zinc ion binding Human NR5A1 UniProtKB UniProtKB {GO:0005515=PMID:14701856, GO:0010467=Reactome:REACT_71, GO:0003700=GO_REF:0000002, GO:0006367=Reactome:REACT_15525, GO:0006366=GO_REF:0000019, GO:0030325=GO_REF:0000019, GO:0003705=PMID:21412441, GO:0007267=PMID:10369247, GO:0001553=GO_REF:0000019, GO:0003707=GO_REF:0000002, GO:0010259=GO_REF:0000019, GO:0005634=GO_REF:0000038, GO:0050810=PMID:10567391, GO:0030154=GO_REF:0000019, GO:0003690=GO_REF:0000019, GO:0005543=PMID:17664281, GO:0045944=GO_REF:0000019, GO:0009888=GO_REF:0000019, GO:0004879=PMID:8205615, GO:2000195=GO_REF:0000019, GO:0003713=PMID:8205615, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000038, GO:0043565=GO_REF:0000019, GO:0007538=PMID:9590178, GO:0051457=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_19207, GO:0042445=GO_REF:0000019, GO:0019899=PMID:17664281, GO:0030522=PMID:8205615, GO:0008584=GO_REF:0000019, GO:2000020=GO_REF:0000019} Q5T6F7 Steroidogenic factor 1 protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0003700=IEA, GO:0006367=TAS, GO:0006366=IEA, GO:0030325=IEA, GO:0003705=IDA, GO:0007267=TAS, GO:0001553=IEA, GO:0003707=IEA, GO:0010259=IEA, GO:0005634=IEA, GO:0050810=TAS, GO:0030154=IEA, GO:0003690=IEA, GO:0005543=IDA, GO:0045944=IEA, GO:0009888=IEA, GO:0004879=TAS, GO:2000195=IEA, GO:0003713=TAS, GO:0003677=IEA, GO:0006351=IEA, GO:0043565=IEA, GO:0007538=TAS, GO:0051457=IEA, GO:0003682=IEA, GO:0008270=IEA, GO:0005654=TAS, GO:0042445=IEA, GO:0019899=IPI, GO:0030522=TAS, GO:0008584=IEA, GO:2000020=IEA} adrenal gland development, cell differentiation, cell-cell signaling, gene expression, hormone metabolic process, intracellular receptor signaling pathway, luteinization, maintenance of protein location in nucleus, male gonad development, multicellular organismal aging, negative regulation of female gonad development, positive regulation of male gonad development, positive regulation of transcription from RNA polymerase II promoter, primary sex determination, regulation of steroid biosynthetic process, tissue development, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent nucleoplasm, nucleus DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, chromatin binding, double-stranded DNA binding, enzyme binding, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, phospholipid binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity, transcription coactivator activity, zinc ion binding Human UniProtKB-KW:KW-0804 NR5A2 BHF-UCL UniProtKB {GO:0005515=PMID:19264593, GO:0010467=Reactome:REACT_71, GO:0003700=PMID:15205472, GO:0006367=Reactome:REACT_15525, GO:0044212=PMID:15205472, GO:0003705=PMID:9786908, GO:0003707=GO_REF:0000002, GO:0005634=PMID:15205472, GO:0009790=PMID:16289203, GO:0005737=PMID:15205472, GO:0003690=GO_REF:0000019, GO:0005543=PMID:15723037, GO:0045944=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0008206=GO_REF:0000019, GO:0004879=PMID:16271724, GO:0045070=PMID:19264593, GO:0042632=GO_REF:0000019, GO:0006355=PMID:15723037, GO:0042592=PMID:16289203, GO:0003677=PMID:16289203, GO:0006351=GO_REF:0000038, GO:0043565=PMID:16289203, GO:0031018=Reactome:REACT_13778, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_19207, GO:0045893=PMID:15205472} O00482 Nuclear receptor subfamily 5 group A member 2 protein 20100114 {GO:0005515=IPI, GO:0010467=TAS, GO:0003700=IDA, GO:0006367=TAS, GO:0044212=IDA, GO:0003705=TAS, GO:0003707=IEA, GO:0005634=IDA, GO:0009790=TAS, GO:0005737=IDA, GO:0003690=IEA, GO:0005543=IDA, GO:0045944=IEA, GO:0042127=IEA, GO:0008206=IEA, GO:0004879=TAS, GO:0045070=IDA, GO:0042632=IEA, GO:0006355=IDA, GO:0042592=NAS, GO:0003677=IDA, GO:0006351=IEA, GO:0043565=IDA, GO:0031018=TAS, GO:0008270=IEA, GO:0005654=TAS, GO:0045893=TAS} bile acid metabolic process, cholesterol homeostasis, embryo development, endocrine pancreas development, gene expression, homeostatic process, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of viral genome replication, regulation of cell proliferation, regulation of transcription, DNA-dependent, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, nucleoplasm, nucleus DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, double-stranded DNA binding, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, phospholipid binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity, transcription regulatory region DNA binding, zinc ion binding Human NR6A1 GOC UniProtKB {GO:0010467=Reactome:REACT_71, GO:0005667=GO_REF:0000024, GO:0006367=Reactome:REACT_15525, GO:0003700=GO_REF:0000002, GO:0008283=PMID:9134503, GO:0007276=GO_REF:0000024, GO:0003707=GO_REF:0000002, GO:0005634=GO_REF:0000038, GO:0000122=GO_REF:0000024, GO:0007283=PMID:9134503, GO:0003677=GO_REF:0000024, GO:0006351=GO_REF:0000038, GO:0042803=GO_REF:0000024, GO:0043565=GO_REF:0000024, GO:0005654=Reactome:REACT_19207, GO:0008270=GO_REF:0000002, GO:0004879=PMID:9134503, GO:0030522=PMID:9134503} Q15406 Nuclear receptor subfamily 6 group A member 1 protein 20130413 {GO:0010467=TAS, GO:0005667=ISS, GO:0006367=TAS, GO:0003700=IEA, GO:0008283=TAS, GO:0007276=ISS, GO:0003707=IEA, GO:0005634=IEA, GO:0000122=ISS, GO:0007283=TAS, GO:0003677=ISS, GO:0006351=IEA, GO:0042803=ISS, GO:0043565=ISS, GO:0005654=TAS, GO:0008270=IEA, GO:0004879=TAS, GO:0030522=TAS} cell proliferation, gamete generation, gene expression, intracellular receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, spermatogenesis, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent nucleoplasm, nucleus, transcription factor complex DNA binding, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity, zinc ion binding Human NRAP UniProtKB UniProtKB {GO:0005916=GO_REF:0000024, GO:0051371=GO_REF:0000024, GO:0008150=GO_REF:0000015, GO:0017166=GO_REF:0000019, GO:0003779=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0030016=GO_REF:0000019, GO:0005927=GO_REF:0000024} Q86VF7 Nebulin-related-anchoring protein protein 20061115 {GO:0005916=ISS, GO:0051371=ISS, GO:0008150=ND, GO:0017166=IEA, GO:0003779=ISS, GO:0008270=IEA, GO:0030016=IEA, GO:0005927=ISS} biological_process fascia adherens, muscle tendon junction, myofibril actin binding, muscle alpha-actinin binding, vinculin binding, zinc ion binding Human UniProtKB:Q80XB4 NRARP MGI UniProtKB {GO:0045746=PMID:19154719, GO:0022407=GO_REF:0000019, GO:0001569=GO_REF:0000019, GO:0001938=GO_REF:0000019, GO:0090263=PMID:19154719, GO:0045581=GO_REF:0000019, GO:0002043=GO_REF:0000019, GO:0000122=GO_REF:0000019} Q7Z6K4 Notch-regulated ankyrin repeat-containing protein protein 20110202 {GO:0045746=IMP, GO:0022407=IEA, GO:0001569=IEA, GO:0001938=IEA, GO:0090263=IMP, GO:0045581=IEA, GO:0002043=IEA, GO:0000122=IEA} blood vessel endothelial cell proliferation involved in sprouting angiogenesis, negative regulation of Notch signaling pathway, negative regulation of T cell differentiation, negative regulation of transcription from RNA polymerase II promoter, patterning of blood vessels, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of endothelial cell proliferation, regulation of cell-cell adhesion Human NRAS Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0048011=Reactome:REACT_11061, GO:0008284=GO_REF:0000019, GO:0030036=GO_REF:0000019, GO:0005886=Reactome:REACT_147697, GO:0035022=GO_REF:0000019, GO:0007264=Reactome:REACT_12077, GO:0003924=GO_REF:0000002, GO:0007265=Reactome:REACT_12033, GO:0050900=Reactome:REACT_12051, GO:0005525=GO_REF:0000037, GO:0043524=GO_REF:0000019, GO:0000186=Reactome:REACT_12005, GO:0007173=Reactome:REACT_9417, GO:0000139=GO_REF:0000039, GO:0008543=Reactome:REACT_9470, GO:0007596=Reactome:REACT_604, GO:0007411=Reactome:REACT_18266, GO:0000165=Reactome:REACT_634, GO:0045087=Reactome:REACT_6802, GO:0008542=GO_REF:0000019, GO:0032228=GO_REF:0000019, GO:0048169=GO_REF:0000019, GO:0051146=GO_REF:0000019} P01111 GTPase NRas protein 20130301 {GO:0008286=TAS, GO:0048011=TAS, GO:0008284=IEA, GO:0030036=IEA, GO:0005886=TAS, GO:0035022=IEA, GO:0007264=TAS, GO:0003924=IEA, GO:0007265=TAS, GO:0050900=TAS, GO:0005525=IEA, GO:0043524=IEA, GO:0000186=TAS, GO:0007173=TAS, GO:0000139=IEA, GO:0008543=TAS, GO:0007596=TAS, GO:0007411=TAS, GO:0000165=TAS, GO:0045087=TAS, GO:0008542=IEA, GO:0032228=IEA, GO:0048169=IEA, GO:0051146=IEA} MAPK cascade, Ras protein signal transduction, actin cytoskeleton organization, activation of MAPKK activity, axon guidance, blood coagulation, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, leukocyte migration, negative regulation of neuron apoptotic process, neurotrophin TRK receptor signaling pathway, positive regulation of Rac protein signal transduction, positive regulation of cell proliferation, regulation of long-term neuronal synaptic plasticity, regulation of synaptic transmission, GABAergic, small GTPase mediated signal transduction, striated muscle cell differentiation, visual learning Golgi membrane, plasma membrane GTP binding, GTPase activity Human NRBF2 LIFEdb UniProtKB {GO:0010467=Reactome:REACT_71, GO:0005737=GO_REF:0000054, GO:0006355=GO_REF:0000037, GO:0006367=Reactome:REACT_15525, GO:0005654=Reactome:REACT_19207} Q96F24 Nuclear receptor-binding factor 2 protein 20100607 {GO:0010467=TAS, GO:0005737=IDA, GO:0006355=IEA, GO:0006367=TAS, GO:0005654=TAS} gene expression, regulation of transcription, DNA-dependent, transcription initiation from RNA polymerase II promoter cytoplasm, nucleoplasm Human NRBP1 Reactome UniProtKB {GO:0006888=PMID:11956649, GO:0010467=Reactome:REACT_71, GO:0048471=GO_REF:0000019, GO:0006367=Reactome:REACT_15525, GO:0004672=GO_REF:0000002, GO:0016020=GO_REF:0000037, GO:0005654=Reactome:REACT_19207, GO:0005938=GO_REF:0000039, GO:0005524=GO_REF:0000002, GO:0030027=GO_REF:0000039, GO:0042803=GO_REF:0000024, GO:0012505=PMID:11956649} Q9UHY1 Nuclear receptor-binding protein protein 20130301 {GO:0006888=IDA, GO:0010467=TAS, GO:0048471=IEA, GO:0006367=TAS, GO:0004672=IEA, GO:0016020=IEA, GO:0005654=TAS, GO:0005938=IEA, GO:0005524=IEA, GO:0030027=IEA, GO:0042803=ISS, GO:0012505=IDA} ER to Golgi vesicle-mediated transport, gene expression, transcription initiation from RNA polymerase II promoter cell cortex, endomembrane system, lamellipodium, membrane, nucleoplasm, perinuclear region of cytoplasm ATP binding, protein homodimerization activity, protein kinase activity Human NRCAM BHF-UCL UniProtKB {GO:0031290=GO_REF:0000019, GO:0043005=PMID:8812479, GO:0030424=GO_REF:0000019, GO:0005886=Reactome:REACT_22108, GO:0030506=PMID:14602817, GO:0045202=GO_REF:0000019, GO:0001525=PMID:11866539, GO:0007409=PMID:8812479, GO:0007417=PMID:8812479, GO:0007416=PMID:8812479, GO:0019227=GO_REF:0000019, GO:0043194=GO_REF:0000024, GO:0030516=PMID:8812479, GO:0016337=PMID:8812479, GO:0008104=GO_REF:0000019, GO:0007413=PMID:8812479, GO:0045162=PMID:14602817, GO:0007411=Reactome:REACT_18266, GO:0005887=PMID:8812479, GO:0045666=PMID:8812479, GO:0010975=GO_REF:0000019, GO:0001764=PMID:11483367, GO:0009897=PMID:8812479} Q92823 Neuronal cell adhesion molecule protein 20120607 {GO:0031290=IEA, GO:0043005=NAS, GO:0030424=IEA, GO:0005886=TAS, GO:0030506=IDA, GO:0045202=IEA, GO:0001525=IEP, GO:0007409=NAS, GO:0007417=NAS, GO:0007416=TAS, GO:0019227=IEA, GO:0043194=ISS, GO:0030516=NAS, GO:0016337=NAS, GO:0008104=IEA, GO:0007413=NAS, GO:0045162=IDA, GO:0007411=TAS, GO:0005887=NAS, GO:0045666=NAS, GO:0010975=IEA, GO:0001764=NAS, GO:0009897=NAS} angiogenesis, axon guidance, axonal fasciculation, axonogenesis, cell-cell adhesion, central nervous system development, clustering of voltage-gated sodium channels, neuron migration, neuronal action potential propagation, positive regulation of neuron differentiation, protein localization, regulation of axon extension, regulation of neuron projection development, retinal ganglion cell axon guidance, synapse assembly axon, axon initial segment, external side of plasma membrane, integral to plasma membrane, neuron projection, plasma membrane, synapse ankyrin binding Human UniProtKB:P97686 NRD1 BHF-UCL UniProtKB {GO:0005515=PMID:18355445, GO:0051044=PMID:18355445, GO:0009986=PMID:12463163, GO:0008283=PMID:12463163, GO:0048408=PMID:12463163, GO:0003824=GO_REF:0000002, GO:0052548=PMID:18355445, GO:0046872=GO_REF:0000037, GO:0005829=PMID:12463163, GO:0005739=GO_REF:0000019, GO:0016477=PMID:15544571, GO:0007528=PMID:9479496, GO:0006508=PMID:9581555, GO:0004222=PMID:9581555} O43847 Nardilysin protein 20081119 {GO:0005515=IPI, GO:0051044=IDA, GO:0009986=TAS, GO:0008283=TAS, GO:0048408=TAS, GO:0003824=IEA, GO:0052548=IDA, GO:0046872=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0016477=TAS, GO:0007528=TAS, GO:0006508=NAS, GO:0004222=NAS} cell migration, cell proliferation, neuromuscular junction development, positive regulation of membrane protein ectodomain proteolysis, proteolysis, regulation of endopeptidase activity cell surface, cytosol, mitochondrion catalytic activity, epidermal growth factor binding, metal ion binding, metalloendopeptidase activity, protein binding Human NRF1 Reactome UniProtKB {GO:0001666=GO_REF:0000019, GO:0006357=PMID:8034649, GO:0031100=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0006091=PMID:7629110, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0051593=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0051602=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0005654=Reactome:REACT_115949, GO:0007005=GO_REF:0000019, GO:0032355=GO_REF:0000019, GO:0044255=Reactome:REACT_22279} Q16656 Nuclear respiratory factor 1 protein 20110909 {GO:0001666=IEA, GO:0006357=TAS, GO:0031100=IEA, GO:0005634=IEA, GO:0044281=TAS, GO:0006091=TAS, GO:0003677=IEA, GO:0006351=IEA, GO:0051593=IEA, GO:0005737=IEA, GO:0051602=IEA, GO:0032496=IEA, GO:0005654=TAS, GO:0007005=IEA, GO:0032355=IEA, GO:0044255=TAS} cellular lipid metabolic process, generation of precursor metabolites and energy, mitochondrion organization, organ regeneration, regulation of transcription from RNA polymerase II promoter, response to electrical stimulus, response to estradiol stimulus, response to folic acid, response to hypoxia, response to lipopolysaccharide, small molecule metabolic process, transcription, DNA-dependent cytoplasm, nucleoplasm, nucleus DNA binding Human NRG1 GOC UniProtKB {GO:0043496=PMID:16412517, GO:0043497=PMID:10559227, GO:0051897=GO_REF:0000019, GO:0003161=GO_REF:0000019, GO:0031594=GO_REF:0000019, GO:0051048=PMID:10559227, GO:0030879=PMID:17432114, GO:0046579=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0009790=GO_REF:0000002, GO:0007171=PMID:1350381, GO:0005737=GO_REF:0000019, GO:0030297=PMID:1348215, GO:0007154=PMID:17432114, GO:0014032=PMID:17432114, GO:0007173=Reactome:REACT_9417, GO:0000165=GO_REF:0000019, GO:0060956=PMID:17336907, GO:0003222=PMID:17336907, GO:0060379=PMID:17336907, GO:0051155=GO_REF:0000024, GO:0007626=GO_REF:0000019, GO:0055007=GO_REF:0000024, GO:0038127=PMID:11389077, GO:0003712=PMID:15073182, GO:0030971=PMID:1348215, GO:0048011=Reactome:REACT_11061, GO:0042177=GO_REF:0000019, GO:0048015=Reactome:REACT_12464, GO:0005102=GO_REF:0000002, GO:0005576=Reactome:REACT_147854, GO:0045213=GO_REF:0000019, GO:0048663=GO_REF:0000019, GO:0005125=PMID:10372964, GO:0007416=GO_REF:0000019, GO:0007399=PMID:17432114, GO:0005176=GO_REF:0000019, GO:0000902=GO_REF:0000019, GO:0016477=GO_REF:0000019, GO:0016020=PMID:8096067, GO:0008543=Reactome:REACT_9470, GO:0005887=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0042060=PMID:16412517, GO:0007422=GO_REF:0000019, GO:0010001=GO_REF:0000019, GO:0045892=PMID:15073182, GO:0008083=PMID:8096067} Q02297 Pro-neuregulin-1, membrane-bound isoform protein 20130413 {GO:0043496=TAS, GO:0043497=IDA, GO:0051897=IEA, GO:0003161=IEA, GO:0031594=IEA, GO:0051048=IDA, GO:0030879=TAS, GO:0046579=IEA, GO:0005634=IEA, GO:0009790=IEA, GO:0007171=NAS, GO:0005737=IEA, GO:0030297=NAS, GO:0007154=TAS, GO:0014032=TAS, GO:0007173=TAS, GO:0000165=IEA, GO:0060956=IDA, GO:0003222=IDA, GO:0060379=IDA, GO:0051155=ISS, GO:0007626=IEA, GO:0055007=ISS, GO:0038127=IDA, GO:0003712=IDA, GO:0030971=NAS, GO:0048011=TAS, GO:0042177=IEA, GO:0048015=TAS, GO:0005102=IEA, GO:0005576=TAS, GO:0045213=IEA, GO:0048663=IEA, GO:0005125=TAS, GO:0007416=IEA, GO:0007399=TAS, GO:0005176=IEA, GO:0000902=IEA, GO:0016477=IEA, GO:0016020=NAS, GO:0008543=TAS, GO:0005887=IEA, GO:0045087=TAS, GO:0042060=TAS, GO:0007422=IEA, GO:0010001=IEA, GO:0045892=IDA, GO:0008083=NAS} ERBB signaling pathway, MAPK cascade, activation of transmembrane receptor protein tyrosine kinase activity, cardiac conduction system development, cardiac muscle cell differentiation, cardiac muscle cell myoblast differentiation, cell communication, cell migration, cell morphogenesis, embryo development, endocardial cell differentiation, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, glial cell differentiation, innate immune response, locomotory behavior, mammary gland development, negative regulation of protein catabolic process, negative regulation of secretion, negative regulation of transcription, DNA-dependent, nervous system development, neural crest cell development, neuron fate commitment, neurotransmitter receptor metabolic process, neurotrophin TRK receptor signaling pathway, peripheral nervous system development, phosphatidylinositol-mediated signaling, positive regulation of Ras protein signal transduction, positive regulation of protein kinase B signaling cascade, positive regulation of striated muscle cell differentiation, regulation of protein heterodimerization activity, regulation of protein homodimerization activity, synapse assembly, ventricular trabecula myocardium morphogenesis, wound healing cytoplasm, extracellular region, integral to plasma membrane, membrane, neuromuscular junction, nucleus ErbB-2 class receptor binding, cytokine activity, growth factor activity, receptor binding, receptor tyrosine kinase binding, transcription cofactor activity, transmembrane receptor protein tyrosine kinase activator activity Human NRG2 Reactome UniProtKB {GO:0007165=PMID:9168114, GO:0048011=Reactome:REACT_11061, GO:0007173=Reactome:REACT_9417, GO:0005886=GO_REF:0000039, GO:0008543=Reactome:REACT_9470, GO:0048015=Reactome:REACT_12464, GO:0045087=Reactome:REACT_6802, GO:0005102=PMID:9168114, GO:0005576=Reactome:REACT_147854, GO:0016021=GO_REF:0000037, GO:0009790=GO_REF:0000002, GO:0008083=GO_REF:0000037} O14511 Pro-neuregulin-2, membrane-bound isoform protein 20130301 {GO:0007165=TAS, GO:0048011=TAS, GO:0007173=TAS, GO:0005886=IEA, GO:0008543=TAS, GO:0048015=TAS, GO:0045087=TAS, GO:0005102=TAS, GO:0005576=TAS, GO:0016021=IEA, GO:0009790=IEA, GO:0008083=IEA} embryo development, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, signal transduction extracellular region, integral to membrane, plasma membrane growth factor activity, receptor binding Human NRG3 GOC UniProtKB {GO:0030971=PMID:9275162, GO:0007389=GO_REF:0000019, GO:0007171=PMID:9275162, GO:0030297=PMID:9275162, GO:0060596=GO_REF:0000019, GO:0005887=PMID:9275162, GO:0005102=GO_REF:0000002, GO:0005576=PMID:9275162, GO:0009790=GO_REF:0000002, GO:0008083=PMID:9275162, GO:0001558=PMID:9275162, GO:0007243=GO_REF:0000019} P56975 Pro-neuregulin-3, membrane-bound isoform protein 20130413 {GO:0030971=NAS, GO:0007389=IEA, GO:0007171=NAS, GO:0030297=NAS, GO:0060596=IEA, GO:0005887=NAS, GO:0005102=IEA, GO:0005576=NAS, GO:0009790=IEA, GO:0008083=NAS, GO:0001558=NAS, GO:0007243=IEA} activation of transmembrane receptor protein tyrosine kinase activity, embryo development, intracellular protein kinase cascade, mammary placode formation, pattern specification process, regulation of cell growth extracellular region, integral to plasma membrane growth factor activity, receptor binding, receptor tyrosine kinase binding, transmembrane receptor protein tyrosine kinase activator activity Human NRG4 Reactome UniProtKB {GO:0048011=Reactome:REACT_11061, GO:0007173=Reactome:REACT_9417, GO:0005886=GO_REF:0000039, GO:0008543=Reactome:REACT_9470, GO:0048015=Reactome:REACT_12464, GO:0045087=Reactome:REACT_6802, GO:0005576=Reactome:REACT_147854, GO:0016021=GO_REF:0000037, GO:0008083=GO_REF:0000037} Q8WWG1 Pro-neuregulin-4, membrane-bound isoform protein 20130301 {GO:0048011=TAS, GO:0007173=TAS, GO:0005886=IEA, GO:0008543=TAS, GO:0048015=TAS, GO:0045087=TAS, GO:0005576=TAS, GO:0016021=IEA, GO:0008083=IEA} epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling extracellular region, integral to membrane, plasma membrane growth factor activity Human NRGN PINC UniProtKB {GO:0007165=PMID:10075657, GO:0005516=GO_REF:0000037, GO:0007399=PMID:10075657} Q92686 Neurogranin protein 20030904 {GO:0007165=TAS, GO:0005516=IEA, GO:0007399=TAS} nervous system development, signal transduction calmodulin binding Human NRIP1 IntAct UniProtKB {GO:0005515=PMID:19401155, GO:0042826=GO_REF:0000019, GO:0019915=GO_REF:0000019, GO:0003714=PMID:10364267, GO:0003713=PMID:11518808, GO:0030331=PMID:7641693, GO:0035257=PMID:11518808, GO:0005634=PMID:12773562, GO:0035259=PMID:12773562, GO:0000122=PMID:10364267, GO:0001543=GO_REF:0000019, GO:0050681=PMID:15572661, GO:0006351=GO_REF:0000037, GO:0046965=GO_REF:0000019, GO:0000118=GO_REF:0000019, GO:0045944=PMID:10364267, GO:0045893=PMID:15572661, GO:0030521=PMID:15572661} P48552 Nuclear receptor-interacting protein 1 protein 20130415 {GO:0005515=IPI, GO:0042826=IEA, GO:0019915=IEA, GO:0003714=IDA, GO:0003713=IDA, GO:0030331=IPI, GO:0035257=IPI, GO:0005634=IDA, GO:0035259=IPI, GO:0000122=IDA, GO:0001543=IEA, GO:0050681=NAS, GO:0006351=IEA, GO:0046965=IEA, GO:0000118=IEA, GO:0045944=IDA, GO:0045893=NAS, GO:0030521=NAS} androgen receptor signaling pathway, lipid storage, negative regulation of transcription from RNA polymerase II promoter, ovarian follicle rupture, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent histone deacetylase complex, nucleus androgen receptor binding, estrogen receptor binding, glucocorticoid receptor binding, histone deacetylase binding, nuclear hormone receptor binding, protein binding, retinoid X receptor binding, transcription coactivator activity, transcription corepressor activity Human UniProtKB:Q13642 NRIP2 LIFEdb UniProtKB {GO:0005737=GO_REF:0000054, GO:0006508=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0004190=GO_REF:0000002, GO:0000122=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q9BQI9 Nuclear receptor-interacting protein 2 protein 20100607 {GO:0005737=IDA, GO:0006508=IEA, GO:0005634=IEA, GO:0004190=IEA, GO:0000122=IEA, GO:0006351=IEA} negative regulation of transcription from RNA polymerase II promoter, proteolysis, transcription, DNA-dependent cytoplasm, nucleus aspartic-type endopeptidase activity Human NRIP3 InterPro UniProtKB {GO:0006508=GO_REF:0000002, GO:0004190=GO_REF:0000002} Q9NQ35 Nuclear receptor-interacting protein 3 protein 20130413 {GO:0006508=IEA, GO:0004190=IEA} proteolysis aspartic-type endopeptidase activity Human InterPro:IPR019103 NRK UniProtKB UniProtKB {GO:0060721=GO_REF:0000019, GO:0005083=GO_REF:0000002, GO:0008285=GO_REF:0000019, GO:0007567=GO_REF:0000019, GO:0004674=GO_REF:0000037, GO:0016301=GO_REF:0000038, GO:0007256=GO_REF:0000019, GO:0005524=GO_REF:0000037} Q7Z2Y5 Nik-related protein kinase protein 20130413 {GO:0060721=IEA, GO:0005083=IEA, GO:0008285=IEA, GO:0007567=IEA, GO:0004674=IEA, GO:0016301=IEA, GO:0007256=IEA, GO:0005524=IEA} activation of JNKK activity, negative regulation of cell proliferation, parturition, regulation of spongiotrophoblast cell proliferation ATP binding, kinase activity, protein serine/threonine kinase activity, small GTPase regulator activity Human UniProtKB-KW:KW-0067 NRL PINC UniProtKB {GO:0043522=PMID:10887186, GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000019, GO:0006366=PMID:8939891, GO:0045944=GO_REF:0000019, GO:0046548=GO_REF:0000019, GO:0007468=PMID:8939891, GO:0005634=GO_REF:0000039, GO:0003677=PMID:1729696, GO:0007601=GO_REF:0000037, GO:0045872=GO_REF:0000019, GO:0050896=GO_REF:0000037} P54845 Neural retina-specific leucine zipper protein protein 20030904 {GO:0043522=IPI, GO:0043565=IEA, GO:0003700=IEA, GO:0006366=TAS, GO:0045944=IEA, GO:0046548=IEA, GO:0007468=TAS, GO:0005634=IEA, GO:0003677=TAS, GO:0007601=IEA, GO:0045872=IEA, GO:0050896=IEA} positive regulation of rhodopsin gene expression, positive regulation of transcription from RNA polymerase II promoter, regulation of rhodopsin gene expression, response to stimulus, retinal rod cell development, transcription from RNA polymerase II promoter, visual perception nucleus DNA binding, leucine zipper domain binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human NRM UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005637=GO_REF:0000039, GO:0005635=PMID:10402458, GO:0016021=GO_REF:0000037} Q8IXM6 Nurim protein 20070914 {GO:0003674=ND, GO:0008150=ND, GO:0005637=IEA, GO:0005635=IDA, GO:0016021=IEA} biological_process integral to membrane, nuclear envelope, nuclear inner membrane molecular_function Human NRP1 InterPro UniProtKB {GO:0035767=GO_REF:0000002, GO:0005886=PMID:21245381, GO:0005883=GO_REF:0000019, GO:0007267=PMID:9288753, GO:0050731=PMID:21245381, GO:0048843=GO_REF:0000019, GO:0060301=PMID:21245381, GO:0046872=GO_REF:0000037, GO:0014911=PMID:21245381, GO:0005829=PMID:21245381, GO:0030426=GO_REF:0000019, GO:0002116=PMID:19909241, GO:0007507=GO_REF:0000019, GO:0007413=GO_REF:0000019, GO:0019838=GO_REF:0000002, GO:0017154=GO_REF:0000002, GO:0007411=GO_REF:0000002, GO:0035729=PMID:21245381, GO:0060666=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0009887=GO_REF:0000002, GO:0005021=GO_REF:0000002, GO:0060627=PMID:21245381, GO:0007155=GO_REF:0000002, GO:0008201=GO_REF:0000037, GO:0048010=GO_REF:0000002, GO:0001569=GO_REF:0000019, GO:0048012=PMID:21245381, GO:0009986=GO_REF:0000019, GO:0009611=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0031410=PMID:21245381, GO:0001525=GO_REF:0000002, GO:0015026=PMID:21245381, GO:0016358=GO_REF:0000019, GO:0048485=GO_REF:0000019, GO:0010595=PMID:21245381, GO:0043235=PMID:21245381, GO:0007165=PMID:9288753, GO:0019955=PMID:19909241, GO:0001938=PMID:21245381, GO:0016020=GO_REF:0000002, GO:0021636=GO_REF:0000019, GO:0071526=PMID:19909241, GO:0048008=PMID:21245381, GO:0016021=GO_REF:0000037} Q5T7F1 Neuropilin-1 protein 20130413 {GO:0035767=IEA, GO:0005886=IDA, GO:0005883=IEA, GO:0007267=TAS, GO:0050731=IMP, GO:0048843=IEA, GO:0060301=TAS, GO:0046872=IEA, GO:0014911=TAS, GO:0005829=IDA, GO:0030426=IEA, GO:0002116=NAS, GO:0007507=IEA, GO:0007413=IEA, GO:0019838=IEA, GO:0017154=IEA, GO:0007411=IEA, GO:0035729=IMP, GO:0060666=IEA, GO:0043025=IEA, GO:0009887=IEA, GO:0005021=IEA, GO:0060627=TAS, GO:0007155=IEA, GO:0008201=IEA, GO:0048010=IEA, GO:0001569=IEA, GO:0048012=IMP, GO:0009986=IEA, GO:0009611=IEA, GO:0005576=IEA, GO:0031410=TAS, GO:0001525=IEA, GO:0015026=TAS, GO:0016358=IEA, GO:0048485=IEA, GO:0010595=TAS, GO:0043235=TAS, GO:0007165=TAS, GO:0019955=NAS, GO:0001938=TAS, GO:0016020=IEA, GO:0021636=IEA, GO:0071526=NAS, GO:0048008=IMP, GO:0016021=IEA} angiogenesis, axon guidance, axonal fasciculation, cell adhesion, cell-cell signaling, cellular response to hepatocyte growth factor stimulus, dendrite development, dichotomous subdivision of terminal units involved in salivary gland branching, endothelial cell chemotaxis, heart development, hepatocyte growth factor receptor signaling pathway, negative regulation of axon extension involved in axon guidance, organ morphogenesis, patterning of blood vessels, platelet-derived growth factor receptor signaling pathway, positive regulation of cytokine activity, positive regulation of endothelial cell migration, positive regulation of endothelial cell proliferation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of smooth muscle cell migration, regulation of vesicle-mediated transport, response to wounding, semaphorin-plexin signaling pathway, signal transduction, sympathetic nervous system development, trigeminal nerve morphogenesis, vascular endothelial growth factor receptor signaling pathway cell surface, cytoplasmic vesicle, cytosol, extracellular region, growth cone, integral to membrane, membrane, neurofilament, neuronal cell body, plasma membrane, receptor complex, semaphorin receptor complex coreceptor activity, cytokine binding, growth factor binding, heparin binding, metal ion binding, semaphorin receptor activity, vascular endothelial growth factor-activated receptor activity Human InterPro:IPR027146 NRP2 BHF-UCL UniProtKB {GO:0048010=Reactome:REACT_12529, GO:0030424=GO_REF:0000019, GO:0005886=Reactome:REACT_12600, GO:0001755=GO_REF:0000019, GO:0050919=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0001525=PMID:11112349, GO:0046872=GO_REF:0000037, GO:0010595=PMID:21245381, GO:0002116=PMID:19909241, GO:0007507=GO_REF:0000019, GO:0019955=PMID:19909241, GO:0019838=PMID:21245381, GO:0017154=PMID:19909241, GO:0016020=PMID:9288754, GO:0001938=PMID:21245381, GO:0007411=PMID:19909241, GO:0004872=PMID:9288754, GO:0005021=PMID:19909241, GO:0016021=PMID:11112349, GO:0007155=PMID:11112349, GO:0008201=GO_REF:0000037} O60462 Neuropilin-2 protein 20110825 {GO:0048010=TAS, GO:0030424=IEA, GO:0005886=TAS, GO:0001755=IEA, GO:0050919=IEA, GO:0005576=IEA, GO:0001525=NAS, GO:0046872=IEA, GO:0010595=TAS, GO:0002116=NAS, GO:0007507=IEA, GO:0019955=NAS, GO:0019838=TAS, GO:0017154=NAS, GO:0016020=TAS, GO:0001938=TAS, GO:0007411=NAS, GO:0004872=TAS, GO:0005021=NAS, GO:0016021=NAS, GO:0007155=NAS, GO:0008201=IEA} angiogenesis, axon guidance, cell adhesion, heart development, negative chemotaxis, neural crest cell migration, positive regulation of endothelial cell migration, positive regulation of endothelial cell proliferation, vascular endothelial growth factor receptor signaling pathway axon, extracellular region, integral to membrane, membrane, plasma membrane, semaphorin receptor complex cytokine binding, growth factor binding, heparin binding, metal ion binding, receptor activity, semaphorin receptor activity, vascular endothelial growth factor-activated receptor activity Human NRSN1 UniProtKB UniProtKB {GO:0030133=PMID:12463420, GO:0043005=GO_REF:0000024, GO:0043025=GO_REF:0000024, GO:0016023=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0030426=GO_REF:0000024, GO:0007399=GO_REF:0000024} Q8IZ57 Neurensin-1 protein 20061201 {GO:0030133=TAS, GO:0043005=ISS, GO:0043025=ISS, GO:0016023=ISS, GO:0016021=IEA, GO:0030426=ISS, GO:0007399=ISS} nervous system development cytoplasmic membrane-bounded vesicle, growth cone, integral to membrane, neuron projection, neuronal cell body, transport vesicle Human UniProtKB:P97799 NRSN2 LIFEdb UniProtKB {GO:0030133=GO_REF:0000024, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005886=GO_REF:0000054, GO:0043025=GO_REF:0000019, GO:0016021=GO_REF:0000029} Q9GZP1 Neurensin-2 protein 20100607 {GO:0030133=ISS, GO:0008150=ND, GO:0003674=ND, GO:0005886=IDA, GO:0043025=IEA, GO:0016021=NAS} biological_process integral to membrane, neuronal cell body, plasma membrane, transport vesicle molecular_function Human NRTN Reactome UniProtKB {GO:0007411=Reactome:REACT_18266, GO:0000165=PMID:8945474, GO:0001755=PMID:15242795, GO:0005102=PMID:10829012, GO:0005576=GO_REF:0000039, GO:0021675=GO_REF:0000019, GO:0008083=GO_REF:0000019, GO:0007169=GO_REF:0000019, GO:0031175=PMID:15242795, GO:0007399=PMID:9286710} Q99748 Neurturin protein 20130301 {GO:0007411=TAS, GO:0000165=TAS, GO:0001755=IDA, GO:0005102=TAS, GO:0005576=IEA, GO:0021675=IEA, GO:0008083=IEA, GO:0007169=IEA, GO:0031175=IDA, GO:0007399=TAS} MAPK cascade, axon guidance, nerve development, nervous system development, neural crest cell migration, neuron projection development, transmembrane receptor protein tyrosine kinase signaling pathway extracellular region growth factor activity, receptor binding Human NRXN1 BHF-UCL UniProtKB {GO:0005515=PMID:11152476, GO:0090129=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:2000311=GO_REF:0000024, GO:2000310=GO_REF:0000024, GO:0016339=GO_REF:0000024, GO:0007411=PMID:1621094, GO:0050885=PMID:19822762, GO:0030534=PMID:19822762, GO:0007612=PMID:19822762, GO:0050839=GO_REF:0000024, GO:0097091=GO_REF:0000024, GO:0051965=GO_REF:0000019, GO:2000821=GO_REF:0000019, GO:0009986=PMID:21424692, GO:2000463=PMID:19822762, GO:0060134=PMID:19822762, GO:0051968=PMID:19822762, GO:0071625=PMID:19896112, GO:0007416=GO_REF:0000002, GO:0042734=GO_REF:0000019, GO:0005887=PMID:1621094, GO:0035176=PMID:18057082, GO:0048306=GO_REF:0000024, GO:0023041=PMID:15797875, GO:0005886=PMID:21424692, GO:0097120=GO_REF:0000024, GO:0030139=GO_REF:0000024, GO:0007269=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0045184=GO_REF:0000024, GO:0097117=GO_REF:0000024, GO:0097116=GO_REF:0000024, GO:0097114=GO_REF:0000024, GO:0097112=GO_REF:0000024, GO:0004872=PMID:1621094, GO:0007155=GO_REF:0000037, GO:0097119=GO_REF:0000024, GO:0007157=GO_REF:0000024, GO:0007158=PMID:15797875, GO:0097118=GO_REF:0000024, GO:0005246=GO_REF:0000019, GO:0005102=GO_REF:0000024, GO:0033130=GO_REF:0000019, GO:0001525=GO_REF:0000024, GO:0044295=GO_REF:0000024, GO:0097104=GO_REF:0000024, GO:0097105=GO_REF:0000024, GO:0060325=PMID:17034946, GO:0043473=PMID:17034946, GO:0016021=GO_REF:0000037, GO:0090004=GO_REF:0000024, GO:0097109=GO_REF:0000024} Q9ULB1 Neurexin-1 protein 20110725 {GO:0005515=IPI, GO:0090129=IEA, GO:0030054=IEA, GO:2000311=ISS, GO:2000310=ISS, GO:0016339=ISS, GO:0007411=TAS, GO:0050885=ISS, GO:0030534=ISS, GO:0007612=ISS, GO:0050839=ISS, GO:0097091=ISS, GO:0051965=IEA, GO:2000821=IEA, GO:0009986=IDA, GO:2000463=ISS, GO:0060134=ISS, GO:0051968=ISS, GO:0071625=IMP, GO:0007416=IEA, GO:0042734=IEA, GO:0005887=TAS, GO:0035176=IMP, GO:0048306=ISS, GO:0023041=TAS, GO:0005886=IC, GO:0097120=ISS, GO:0030139=ISS, GO:0007269=IEA, GO:0046872=IEA, GO:0045184=ISS, GO:0097117=ISS, GO:0097116=ISS, GO:0097114=ISS, GO:0097112=ISS, GO:0004872=TAS, GO:0007155=IEA, GO:0097119=ISS, GO:0007157=ISS, GO:0007158=TAS, GO:0097118=ISS, GO:0005246=IEA, GO:0005102=ISS, GO:0033130=IEA, GO:0001525=ISS, GO:0044295=ISS, GO:0097104=ISS, GO:0097105=ISS, GO:0060325=IMP, GO:0043473=IMP, GO:0016021=IEA, GO:0090004=ISS, GO:0097109=ISS} N-methyl-D-aspartate receptor clustering, adult behavior, angiogenesis, axon guidance, calcium-dependent cell-cell adhesion, cell adhesion, establishment of protein localization, face morphogenesis, gamma-aminobutyric acid receptor clustering, gephyrin clustering, guanylate kinase-associated protein clustering, heterophilic cell-cell adhesion, learning, neuroligin clustering, neuromuscular process controlling balance, neuron cell-cell adhesion, neuronal signal transduction, neurotransmitter secretion, pigmentation, positive regulation of establishment of protein localization to plasma membrane, positive regulation of excitatory postsynaptic membrane potential, positive regulation of synapse assembly, positive regulation of synapse maturation, positive regulation of synaptic transmission, glutamatergic, postsynaptic density protein 95 clustering, postsynaptic membrane assembly, prepulse inhibition, presynaptic membrane assembly, receptor localization to synapse, regulation of N-methyl-D-aspartate selective glutamate receptor activity, regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity, regulation of grooming behavior, social behavior, synapse assembly, synaptic vesicle clustering, vocalization behavior axonal growth cone, cell junction, cell surface, endocytic vesicle, integral to membrane, integral to plasma membrane, plasma membrane, presynaptic membrane acetylcholine receptor binding, calcium channel regulator activity, calcium-dependent protein binding, cell adhesion molecule binding, metal ion binding, neuroligin family protein binding, protein binding, receptor activity, receptor binding Human NRXN2 BHF-UCL UniProtKB {GO:0097104=GO_REF:0000024, GO:0097116=GO_REF:0000024, GO:0005246=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037, GO:0050839=GO_REF:0000024, GO:0007416=GO_REF:0000002, GO:0097119=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0007269=GO_REF:0000019, GO:0097118=GO_REF:0000024} Q9P2S2 Neurexin-2 protein 20110818 {GO:0097104=ISS, GO:0097116=ISS, GO:0005246=IEA, GO:0016021=IEA, GO:0007155=IEA, GO:0050839=ISS, GO:0007416=IEA, GO:0097119=ISS, GO:0046872=IEA, GO:0007269=IEA, GO:0097118=ISS} cell adhesion, gephyrin clustering, neuroligin clustering, neurotransmitter secretion, postsynaptic density protein 95 clustering, postsynaptic membrane assembly, synapse assembly integral to membrane calcium channel regulator activity, cell adhesion molecule binding, metal ion binding Human UniProtKB:Q3UGZ9 NRXN3 PINC UniProtKB {GO:0051965=GO_REF:0000002, GO:0090129=GO_REF:0000002, GO:0007411=PMID:1621094, GO:0005887=PMID:1621094, GO:0005246=GO_REF:0000019, GO:0004872=GO_REF:0000002, GO:0001525=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037, GO:0007416=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0007269=GO_REF:0000019} Q9Y4C0 Neurexin-3 protein 20030904 {GO:0051965=IEA, GO:0090129=IEA, GO:0007411=TAS, GO:0005887=TAS, GO:0005246=IEA, GO:0004872=IEA, GO:0001525=ISS, GO:0016021=IEA, GO:0007155=IEA, GO:0007416=IEA, GO:0046872=IEA, GO:0007269=IEA} angiogenesis, axon guidance, cell adhesion, neurotransmitter secretion, positive regulation of synapse assembly, positive regulation of synapse maturation, synapse assembly integral to membrane, integral to plasma membrane calcium channel regulator activity, metal ion binding, receptor activity Human NSA2 UniProtKB UniProtKB {GO:0030529=GO_REF:0000037, GO:0006364=GO_REF:0000037, GO:0005730=GO_REF:0000039} O95478 Ribosome biogenesis protein NSA2 homolog protein 20130413 {GO:0030529=IEA, GO:0006364=IEA, GO:0005730=IEA} rRNA processing nucleolus, ribonucleoprotein complex Human UniProtKB-SubCell:SL-0188 NSD1 GOC UniProtKB {GO:0003712=PMID:11509567, GO:0016922=GO_REF:0000024, GO:0034770=GO_REF:0000024, GO:0005694=GO_REF:0000039, GO:0003714=GO_REF:0000024, GO:0016571=GO_REF:0000024, GO:0010452=PMID:21196496, GO:0030331=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0000122=GO_REF:0000024, GO:0050681=PMID:11509567, GO:0042974=GO_REF:0000024, GO:0001702=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0042054=GO_REF:0000019, GO:0046966=GO_REF:0000024, GO:0046965=GO_REF:0000024, GO:0042799=GO_REF:0000024, GO:0003682=GO_REF:0000024, GO:0046975=PMID:21196496, GO:0008270=PMID:21196496, GO:0045893=PMID:11509567} Q96L73 Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific protein 20130413 {GO:0003712=IDA, GO:0016922=ISS, GO:0034770=ISS, GO:0005694=IEA, GO:0003714=ISS, GO:0016571=ISS, GO:0010452=IDA, GO:0030331=ISS, GO:0005634=IEA, GO:0000122=ISS, GO:0050681=IDA, GO:0042974=ISS, GO:0001702=IEA, GO:0006351=IEA, GO:0042054=IEA, GO:0046966=ISS, GO:0046965=ISS, GO:0042799=ISS, GO:0003682=ISS, GO:0046975=IDA, GO:0008270=IDA, GO:0045893=IDA} gastrulation with mouth forming second, histone H3-K36 methylation, histone H4-K20 methylation, histone methylation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent chromosome, nucleus androgen receptor binding, chromatin binding, estrogen receptor binding, histone methyltransferase activity, histone methyltransferase activity (H3-K36 specific), histone methyltransferase activity (H4-K20 specific), ligand-dependent nuclear receptor binding, retinoic acid receptor binding, retinoid X receptor binding, thyroid hormone receptor binding, transcription cofactor activity, transcription corepressor activity, zinc ion binding Human UniProtKB:O88491 NSDHL HPA UniProtKB {GO:0006695=Reactome:REACT_9405, GO:0006694=GO_REF:0000002, GO:0005783=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0003854=GO_REF:0000002, GO:0007224=GO_REF:0000019, GO:0043231=GO_REF:0000052, GO:0047012=GO_REF:0000003, GO:0060716=GO_REF:0000019, GO:0005789=Reactome:REACT_10053, GO:0016021=GO_REF:0000037, GO:0001942=GO_REF:0000019, GO:0008203=GO_REF:0000019} Q15738 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating protein 20101115 {GO:0006695=TAS, GO:0006694=IEA, GO:0005783=IDA, GO:0044281=TAS, GO:0003854=IEA, GO:0007224=IEA, GO:0043231=IDA, GO:0047012=IEA, GO:0060716=IEA, GO:0005789=TAS, GO:0016021=IEA, GO:0001942=IEA, GO:0008203=IEA} cholesterol biosynthetic process, cholesterol metabolic process, hair follicle development, labyrinthine layer blood vessel development, small molecule metabolic process, smoothened signaling pathway, steroid biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle 3-beta-hydroxy-delta5-steroid dehydrogenase activity, sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity Human NSF HPA UniProtKB {GO:0019905=GO_REF:0000019, GO:0005515=PMID:16417406, GO:0042623=GO_REF:0000019, GO:0005886=PMID:15613468, GO:0007268=Reactome:REACT_13685, GO:0015031=GO_REF:0000037, GO:0006887=PMID:15613468, GO:0030165=PMID:15613468, GO:0005524=GO_REF:0000037, GO:0032403=PMID:15613468, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_18320, GO:0005737=GO_REF:0000052, GO:0045026=PMID:15613468, GO:0001921=PMID:15613468, GO:0006813=GO_REF:0000019} P46459 Vesicle-fusing ATPase protein 20080818 {GO:0019905=IEA, GO:0005515=IPI, GO:0042623=IEA, GO:0005886=IDA, GO:0007268=TAS, GO:0015031=IEA, GO:0006887=TAS, GO:0030165=IPI, GO:0005524=IEA, GO:0032403=IDA, GO:0046872=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0045026=TAS, GO:0001921=IDA, GO:0006813=IEA} exocytosis, plasma membrane fusion, positive regulation of receptor recycling, potassium ion transport, protein transport, synaptic transmission cytoplasm, cytosol, plasma membrane ATP binding, ATPase activity, coupled, PDZ domain binding, metal ion binding, protein binding, protein complex binding, syntaxin binding Human NSFL1C UniProtKB UniProtKB {GO:0005795=GO_REF:0000039, GO:0005694=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0008289=GO_REF:0000037} Q9UNZ2 NSFL1 cofactor p47 protein 20130413 {GO:0005795=IEA, GO:0005694=IEA, GO:0005634=IEA, GO:0008289=IEA} Golgi stack, chromosome, nucleus lipid binding Human UniProtKB-SubCell:SL-0135 NSL1 HPA UniProtKB {GO:0005515=PMID:17981135, GO:0000236=Reactome:REACT_682, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005829=Reactome:REACT_150414, GO:0005737=GO_REF:0000052, GO:0007059=GO_REF:0000037, GO:0000087=Reactome:REACT_910, GO:0000444=PMID:16585270, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q96IY1 Kinetochore-associated protein NSL1 homolog protein 20120912 {GO:0005515=IPI, GO:0000236=TAS, GO:0005886=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0005829=TAS, GO:0005737=IDA, GO:0007059=IEA, GO:0000087=TAS, GO:0000444=IDA, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, cell division, chromosome segregation, mitotic anaphase, mitotic cell cycle, mitotic prometaphase MIS12/MIND type complex, cytoplasm, cytosol, nucleolus, nucleus, plasma membrane protein binding Human NSMAF IntAct UniProtKB {GO:0005515=PMID:20562859, GO:0007165=PMID:8808629, GO:0005737=PMID:8808629, GO:0006672=PMID:8808629, GO:0005057=PMID:8808629} Q92636 Protein FAN protein 20130415 {GO:0005515=IPI, GO:0007165=TAS, GO:0005737=TAS, GO:0006672=TAS, GO:0005057=TAS} ceramide metabolic process, signal transduction cytoplasm protein binding, receptor signaling protein activity Human UniProtKB:Q9H0R8 NSMCE1 GOC UniProtKB {GO:0035556=GO_REF:0000002, GO:0004842=PMID:20864041, GO:0000781=GO_REF:0000039, GO:0016567=PMID:20864041, GO:0006281=GO_REF:0000037, GO:0030915=PMID:18086888, GO:2001022=PMID:18086888, GO:0005634=GO_REF:0000039, GO:0006310=GO_REF:0000037, GO:0008270=GO_REF:0000002} Q8WV22 Non-structural maintenance of chromosomes element 1 homolog protein 20130413 {GO:0035556=IEA, GO:0004842=IDA, GO:0000781=IEA, GO:0016567=IDA, GO:0006281=IEA, GO:0030915=IDA, GO:2001022=IMP, GO:0005634=IEA, GO:0006310=IEA, GO:0008270=IEA} DNA recombination, DNA repair, intracellular signal transduction, positive regulation of response to DNA damage stimulus, protein ubiquitination Smc5-Smc6 complex, chromosome, telomeric region, nucleus ubiquitin-protein ligase activity, zinc ion binding Human NSMCE2 UniProtKB UniProtKB {GO:0000781=PMID:17589526, GO:0030915=PMID:18086888, GO:0016925=GO_REF:0000041, GO:0045842=PMID:19502785, GO:0006303=PMID:16810316, GO:0007067=GO_REF:0000037, GO:0000724=PMID:16810316, GO:0019789=PMID:17589526, GO:0016605=PMID:17589526, GO:0000722=PMID:17589526, GO:0008270=GO_REF:0000002, GO:0034184=PMID:19502785, GO:0090398=PMID:17589526, GO:0051301=GO_REF:0000037} Q96MF7 E3 SUMO-protein ligase NSE2 protein 20120214 {GO:0000781=IDA, GO:0030915=IDA, GO:0016925=IEA, GO:0045842=IMP, GO:0006303=IMP, GO:0007067=IEA, GO:0000724=IMP, GO:0019789=IDA, GO:0016605=IDA, GO:0000722=IMP, GO:0008270=IEA, GO:0034184=IMP, GO:0090398=IMP, GO:0051301=IEA} cell division, cellular senescence, double-strand break repair via homologous recombination, double-strand break repair via nonhomologous end joining, mitosis, positive regulation of maintenance of mitotic sister chromatid cohesion, positive regulation of mitotic metaphase/anaphase transition, protein sumoylation, telomere maintenance via recombination PML body, Smc5-Smc6 complex, chromosome, telomeric region SUMO ligase activity, zinc ion binding Human NSMCE4A UniProtKB UniProtKB {GO:0000781=GO_REF:0000039, GO:0006281=GO_REF:0000037, GO:0030915=PMID:18086888, GO:2001022=PMID:18086888, GO:0006310=GO_REF:0000037, GO:0005634=GO_REF:0000039} Q9NXX6 Non-structural maintenance of chromosomes element 4 homolog A protein 20120210 {GO:0000781=IEA, GO:0006281=IEA, GO:0030915=IDA, GO:2001022=IMP, GO:0006310=IEA, GO:0005634=IEA} DNA recombination, DNA repair, positive regulation of response to DNA damage stimulus Smc5-Smc6 complex, chromosome, telomeric region, nucleus Human NSRP1 LIFEdb UniProtKB {GO:0005515=PMID:21296756, GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0032502=PMID:21296756, GO:0016607=GO_REF:0000054, GO:0000381=PMID:21296756, GO:0030529=PMID:21296756, GO:0005634=PMID:21296756, GO:0003729=PMID:21296756, GO:0006913=PMID:21296756} Q9H0G5 Nuclear speckle splicing regulatory protein 1 protein 20100607 {GO:0005515=IPI, GO:0008380=IEA, GO:0006397=IEA, GO:0032502=IMP, GO:0016607=IDA, GO:0000381=IDA, GO:0030529=IDA, GO:0005634=IDA, GO:0003729=IDA, GO:0006913=IDA} RNA splicing, developmental process, mRNA processing, nucleocytoplasmic transport, regulation of alternative mRNA splicing, via spliceosome nuclear speck, nucleus, ribonucleoprotein complex mRNA binding, protein binding Human NSUN2 HPA UniProtKB {GO:0016428=PMID:17071714, GO:0005737=PMID:17071714, GO:0007067=GO_REF:0000037, GO:0000049=GO_REF:0000037, GO:0005730=PMID:17071714, GO:0030488=PMID:17071714, GO:0005819=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0051301=GO_REF:0000037} Q08J23 tRNA (cytosine(34)-C(5))-methyltransferase protein 20110516 {GO:0016428=IDA, GO:0005737=IDA, GO:0007067=IEA, GO:0000049=IEA, GO:0005730=IDA, GO:0030488=IDA, GO:0005819=IEA, GO:0005634=IDA, GO:0051301=IEA} cell division, mitosis, tRNA methylation cytoplasm, nucleolus, nucleus, spindle tRNA (cytosine-5-)-methyltransferase activity, tRNA binding Human NSUN3 UniProtKB UniProtKB {GO:0008168=GO_REF:0000037} Q9H649 Putative methyltransferase NSUN3 protein 20130413 {GO:0008168=IEA} methyltransferase activity Human UniProtKB-KW:KW-0489 NSUN4 MGI UniProtKB {GO:0006364=GO_REF:0000037, GO:0008168=GO_REF:0000037, GO:0005762=PMID:21531335} Q96CB9 5-methylcytosine rRNA methyltransferase NSUN4 protein 20111227 {GO:0006364=IEA, GO:0008168=IEA, GO:0005762=IDA} rRNA processing mitochondrial large ribosomal subunit methyltransferase activity Human NSUN5 UniProtKB UniProtKB {GO:0008168=GO_REF:0000037} Q96P11 Putative methyltransferase NSUN5 protein 20130413 {GO:0008168=IEA} methyltransferase activity Human UniProtKB-KW:KW-0489 NSUN6 UniProtKB UniProtKB {GO:0003723=GO_REF:0000002, GO:0008168=GO_REF:0000037} Q8TEA1 Putative methyltransferase NSUN6 protein 20130413 {GO:0003723=IEA, GO:0008168=IEA} RNA binding, methyltransferase activity Human UniProtKB-KW:KW-0489 NT5C HPA UniProtKB {GO:0009223=PMID:10681516, GO:0055086=Reactome:REACT_1698, GO:0005634=PMID:10681516, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_1972, GO:0005739=GO_REF:0000019, GO:0016791=GO_REF:0000002, GO:0046135=Reactome:REACT_1023, GO:0006195=Reactome:REACT_2086, GO:0009264=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0019103=PMID:10681516, GO:0006144=Reactome:REACT_522, GO:0016311=PMID:10681516, GO:0008253=Reactome:REACT_1972, GO:0008252=PMID:10681516, GO:0006206=Reactome:REACT_957} Q8TCD5 5'(3')-deoxyribonucleotidase, cytosolic type protein 20100326 {GO:0009223=IDA, GO:0055086=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0016791=IEA, GO:0046135=TAS, GO:0006195=TAS, GO:0009264=IEA, GO:0005737=IDA, GO:0019103=IDA, GO:0006144=TAS, GO:0016311=IDA, GO:0008253=EXP, GO:0008252=IDA, GO:0006206=TAS} deoxyribonucleotide catabolic process, dephosphorylation, nucleobase-containing small molecule metabolic process, purine nucleobase metabolic process, purine nucleotide catabolic process, pyrimidine deoxyribonucleotide catabolic process, pyrimidine nucleobase metabolic process, pyrimidine nucleoside catabolic process, small molecule metabolic process cytoplasm, cytosol, mitochondrion, nucleus 5'-nucleotidase activity, metal ion binding, nucleotidase activity, phosphatase activity, pyrimidine nucleotide binding Human NT5C1A Reactome UniProtKB {GO:0000287=GO_REF:0000002, GO:0046085=GO_REF:0000019, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_2012, GO:0006195=Reactome:REACT_2086, GO:0046135=Reactome:REACT_1023, GO:0000166=GO_REF:0000037, GO:0006144=Reactome:REACT_522, GO:0008253=Reactome:REACT_2012, GO:0009116=PMID:11133996, GO:0009128=GO_REF:0000019, GO:0006206=Reactome:REACT_957} Q9BXI3 Cytosolic 5'-nucleotidase 1A protein 20130213 {GO:0000287=IEA, GO:0046085=IEA, GO:0055086=TAS, GO:0044281=TAS, GO:0005829=TAS, GO:0006195=TAS, GO:0046135=TAS, GO:0000166=IEA, GO:0006144=TAS, GO:0008253=EXP, GO:0009116=NAS, GO:0009128=IEA, GO:0006206=TAS} adenosine metabolic process, nucleobase-containing small molecule metabolic process, nucleoside metabolic process, purine nucleobase metabolic process, purine nucleoside monophosphate catabolic process, purine nucleotide catabolic process, pyrimidine nucleobase metabolic process, pyrimidine nucleoside catabolic process, small molecule metabolic process cytosol 5'-nucleotidase activity, magnesium ion binding, nucleotide binding Human NT5C1B Reactome UniProtKB {GO:0006195=Reactome:REACT_2086, GO:0005737=GO_REF:0000002, GO:0000287=GO_REF:0000002, GO:0000166=GO_REF:0000002, GO:0006144=Reactome:REACT_522, GO:0008253=GO_REF:0000003, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0009117=GO_REF:0000002, GO:0005829=Reactome:REACT_1556} Q96P26 Cytosolic 5'-nucleotidase 1B protein 20130301 {GO:0006195=TAS, GO:0005737=IEA, GO:0000287=IEA, GO:0000166=IEA, GO:0006144=TAS, GO:0008253=IEA, GO:0055086=TAS, GO:0044281=TAS, GO:0009117=IEA, GO:0005829=TAS} nucleobase-containing small molecule metabolic process, nucleotide metabolic process, purine nucleobase metabolic process, purine nucleotide catabolic process, small molecule metabolic process cytoplasm, cytosol 5'-nucleotidase activity, magnesium ion binding, nucleotide binding Human NT5C2 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0006195=Reactome:REACT_2086, GO:0050146=Reactome:REACT_120749, GO:0017144=Reactome:REACT_121388, GO:0000166=GO_REF:0000037, GO:0006144=Reactome:REACT_522, GO:0008253=Reactome:REACT_1336, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_120749} P49902 Cytosolic purine 5'-nucleotidase protein 20130415 {GO:0005515=IPI, GO:0006195=TAS, GO:0050146=TAS, GO:0017144=TAS, GO:0000166=IEA, GO:0006144=TAS, GO:0008253=EXP, GO:0055086=TAS, GO:0044281=TAS, GO:0046872=IEA, GO:0005829=TAS} drug metabolic process, nucleobase-containing small molecule metabolic process, purine nucleobase metabolic process, purine nucleotide catabolic process, small molecule metabolic process cytosol 5'-nucleotidase activity, metal ion binding, nucleoside phosphotransferase activity, nucleotide binding, protein binding Human UniProtKB:Q86TA1 NT5DC1 UniProtKB UniProtKB {GO:0016787=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q5TFE4 5'-nucleotidase domain-containing protein 1 protein 20130413 {GO:0016787=IEA, GO:0046872=IEA} hydrolase activity, metal ion binding Human UniProtKB-KW:KW-0479 NT5DC2 UniProtKB UniProtKB {GO:0016787=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q9H857 5'-nucleotidase domain-containing protein 2 protein 20130413 {GO:0016787=IEA, GO:0046872=IEA} hydrolase activity, metal ion binding Human UniProtKB-KW:KW-0479 NT5DC3 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0016787=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0005829=GO_REF:0000019} Q86UY8 5'-nucleotidase domain-containing protein 3 protein 20130413 {GO:0005739=IEA, GO:0016787=IEA, GO:0046872=IEA, GO:0005829=IEA} cytosol, mitochondrion hydrolase activity, metal ion binding Human Ensembl:ENSMUSP00000096994 NT5DC4 UniProtKB UniProtKB {GO:0016787=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q86YG4 5'-nucleotidase domain-containing protein 4 protein 20130413 {GO:0016787=IEA, GO:0046872=IEA} hydrolase activity, metal ion binding Human UniProtKB-KW:KW-0479 NT5E HPA UniProtKB {GO:0005886=GO_REF:0000052, GO:0016788=GO_REF:0000002, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0031225=GO_REF:0000037, GO:0046086=GO_REF:0000019, GO:0006259=PMID:2129526, GO:0009166=GO_REF:0000002, GO:0046872=GO_REF:0000002, GO:0006196=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0046135=Reactome:REACT_1023, GO:0006195=Reactome:REACT_2086, GO:0000166=GO_REF:0000002, GO:0016020=PMID:2129526, GO:0016787=GO_REF:0000002, GO:0006144=Reactome:REACT_522, GO:0050728=GO_REF:0000019, GO:0008253=Reactome:REACT_1236, GO:0006206=Reactome:REACT_957} Q96B60 5'-nucleotidase protein 20100326 {GO:0005886=IDA, GO:0016788=IEA, GO:0055086=TAS, GO:0044281=TAS, GO:0031225=IEA, GO:0046086=IEA, GO:0006259=TAS, GO:0009166=IEA, GO:0046872=IEA, GO:0006196=IEA, GO:0005737=IDA, GO:0046135=TAS, GO:0006195=TAS, GO:0000166=IEA, GO:0016020=TAS, GO:0016787=IEA, GO:0006144=TAS, GO:0050728=IEA, GO:0008253=EXP, GO:0006206=TAS} AMP catabolic process, DNA metabolic process, adenosine biosynthetic process, negative regulation of inflammatory response, nucleobase-containing small molecule metabolic process, nucleotide catabolic process, purine nucleobase metabolic process, purine nucleotide catabolic process, pyrimidine nucleobase metabolic process, pyrimidine nucleoside catabolic process, small molecule metabolic process anchored to membrane, cytoplasm, membrane, plasma membrane 5'-nucleotidase activity, hydrolase activity, hydrolase activity, acting on ester bonds, metal ion binding, nucleotide binding Human NT5M Reactome UniProtKB {GO:0009223=PMID:10899995, GO:0046079=GO_REF:0000019, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0006260=PMID:10899995, GO:0005739=PMID:10899995, GO:0016791=GO_REF:0000002, GO:0046135=Reactome:REACT_1023, GO:0000166=GO_REF:0000037, GO:0005759=Reactome:REACT_1389, GO:0008253=Reactome:REACT_1389, GO:0008252=PMID:10899995, GO:0006206=Reactome:REACT_957} Q9NPB1 5'(3')-deoxyribonucleotidase, mitochondrial protein 20130213 {GO:0009223=TAS, GO:0046079=IEA, GO:0055086=TAS, GO:0044281=TAS, GO:0046872=IEA, GO:0006260=TAS, GO:0005739=TAS, GO:0016791=IEA, GO:0046135=TAS, GO:0000166=IEA, GO:0005759=TAS, GO:0008253=EXP, GO:0008252=TAS, GO:0006206=TAS} DNA replication, dUMP catabolic process, nucleobase-containing small molecule metabolic process, pyrimidine deoxyribonucleotide catabolic process, pyrimidine nucleobase metabolic process, pyrimidine nucleoside catabolic process, small molecule metabolic process mitochondrial matrix, mitochondrion 5'-nucleotidase activity, metal ion binding, nucleotidase activity, nucleotide binding, phosphatase activity Human NTF3 GOC UniProtKB {GO:0032856=PMID:23027130, GO:0008284=PMID:23027130, GO:0007267=PMID:2236018, GO:0050732=PMID:23027130, GO:2000251=PMID:23027130, GO:0050731=PMID:23027130, GO:0021675=GO_REF:0000019, GO:0000187=PMID:23027130, GO:0033138=PMID:23027130, GO:0043524=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0032148=PMID:23027130, GO:0005165=GO_REF:0000002, GO:0030335=PMID:23027130, GO:0042490=GO_REF:0000019, GO:0048406=GO_REF:0000019, GO:0042552=GO_REF:0000019, GO:0005102=PMID:2236018, GO:0050804=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0045687=GO_REF:0000019, GO:0007274=GO_REF:0000019, GO:0042056=PMID:23027130, GO:0050918=PMID:23027130, GO:0048484=GO_REF:0000019, GO:0007399=PMID:1542658, GO:0050930=PMID:23027130, GO:0007165=PMID:2236018, GO:0008544=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0007403=GO_REF:0000019, GO:0007422=GO_REF:0000019, GO:0016023=GO_REF:0000019, GO:0008083=PMID:23027130, GO:0007169=PMID:23027130, GO:0051145=GO_REF:0000019} P20783 Neurotrophin-3 protein 20130413 {GO:0032856=IDA, GO:0008284=IDA, GO:0007267=TAS, GO:0050732=IDA, GO:2000251=IDA, GO:0050731=IDA, GO:0021675=IEA, GO:0000187=IDA, GO:0033138=IDA, GO:0043524=IEA, GO:0007411=IEA, GO:0045944=IEA, GO:0032148=IDA, GO:0005165=IEA, GO:0030335=IDA, GO:0042490=IEA, GO:0048406=IEA, GO:0042552=IEA, GO:0005102=TAS, GO:0050804=IEA, GO:0005576=IEA, GO:0045687=IEA, GO:0007274=IEA, GO:0042056=IDA, GO:0050918=IDA, GO:0048484=IEA, GO:0007399=TAS, GO:0050930=IDA, GO:0007165=TAS, GO:0008544=IEA, GO:0007420=IEA, GO:0007403=IEA, GO:0007422=IEA, GO:0016023=IEA, GO:0008083=IDA, GO:0007169=IDA, GO:0051145=IEA} activation of MAPK activity, activation of Ras GTPase activity, activation of protein kinase B activity, axon guidance, brain development, cell-cell signaling, enteric nervous system development, epidermis development, glial cell fate determination, induction of positive chemotaxis, mechanoreceptor differentiation, myelination, negative regulation of neuron apoptotic process, negative regulation of peptidyl-tyrosine phosphorylation, nerve development, nervous system development, neuromuscular synaptic transmission, peripheral nervous system development, positive chemotaxis, positive regulation of actin cytoskeleton reorganization, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of glial cell differentiation, positive regulation of peptidyl-serine phosphorylation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of transcription from RNA polymerase II promoter, regulation of synaptic transmission, signal transduction, smooth muscle cell differentiation, transmembrane receptor protein tyrosine kinase signaling pathway cytoplasmic membrane-bounded vesicle, extracellular region chemoattractant activity, growth factor activity, nerve growth factor binding, neurotrophin receptor binding, receptor binding Human NTF4 UniProtKB UniProtKB {GO:0008344=PMID:10681461, GO:0042490=GO_REF:0000019, GO:0008052=PMID:10479455, GO:0008544=PMID:9973328, GO:0007616=PMID:10869436, GO:0007402=PMID:10681461, GO:0005788=PMID:925010, GO:0005576=PMID:10908605, GO:0008083=GO_REF:0000037} P34130 Neurotrophin-4 protein 20091117 {GO:0008344=ISS, GO:0042490=IEA, GO:0008052=ISS, GO:0008544=ISS, GO:0007616=ISS, GO:0007402=ISS, GO:0005788=ISS, GO:0005576=ISS, GO:0008083=IEA} adult locomotory behavior, epidermis development, ganglion mother cell fate determination, long-term memory, mechanoreceptor differentiation, sensory organ boundary specification endoplasmic reticulum lumen, extracellular region growth factor activity Human UniProtKB:Q80VU4 NTHL1 Reactome UniProtKB {GO:0003906=PMID:8990169, GO:0005515=PMID:15358233, GO:0051539=GO_REF:0000037, GO:0005634=PMID:12531031, GO:0003677=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0005739=GO_REF:0000019, GO:0019104=PMID:10882850, GO:0006281=Reactome:REACT_216, GO:0004519=GO_REF:0000002, GO:0003690=PMID:15358233, GO:0006296=PMID:8990169, GO:0006284=Reactome:REACT_1104, GO:0045008=Reactome:REACT_2156, GO:0006285=Reactome:REACT_804, GO:0005654=Reactome:REACT_2255} P78549 Endonuclease III-like protein 1 protein 20130213 {GO:0003906=IDA, GO:0005515=IPI, GO:0051539=IEA, GO:0005634=IDA, GO:0003677=IEA, GO:0046872=IEA, GO:0005739=IEA, GO:0019104=IDA, GO:0006281=TAS, GO:0004519=IEA, GO:0003690=IDA, GO:0006296=IDA, GO:0006284=TAS, GO:0045008=TAS, GO:0006285=TAS, GO:0005654=TAS} DNA repair, base-excision repair, base-excision repair, AP site formation, depyrimidination, nucleotide-excision repair, DNA incision, 5'-to lesion mitochondrion, nucleoplasm, nucleus 4 iron, 4 sulfur cluster binding, DNA N-glycosylase activity, DNA binding, DNA-(apurinic or apyrimidinic site) lyase activity, double-stranded DNA binding, endonuclease activity, metal ion binding, protein binding Human NTM IntAct UniProtKB {GO:0005515=PMID:21982860, GO:0008038=PMID:7891157, GO:0005886=GO_REF:0000039, GO:0031225=GO_REF:0000037, GO:0007155=GO_REF:0000037} Q9P121 Neurotrimin protein 20130415 {GO:0005515=IPI, GO:0008038=TAS, GO:0005886=IEA, GO:0031225=IEA, GO:0007155=IEA} cell adhesion, neuron recognition anchored to membrane, plasma membrane protein binding Human UniProtKB:Q7Z3B1 NTN1 Reactome UniProtKB {GO:0030334=GO_REF:0000019, GO:0005515=PMID:10102268, GO:0008284=GO_REF:0000019, GO:0042472=GO_REF:0000019, GO:0045773=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0005576=Reactome:REACT_22309, GO:0005604=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0016337=GO_REF:0000019, GO:0040023=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0030517=GO_REF:0000019, GO:0001764=GO_REF:0000019, GO:0060603=GO_REF:0000019} O95631 Netrin-1 protein 20080716 {GO:0030334=IEA, GO:0005515=IPI, GO:0008284=IEA, GO:0042472=IEA, GO:0045773=IEA, GO:0006915=IEA, GO:0005576=TAS, GO:0005604=IEA, GO:0005737=IEA, GO:0016337=IEA, GO:0040023=IEA, GO:0007411=TAS, GO:0030517=IEA, GO:0001764=IEA, GO:0060603=IEA} apoptotic process, axon guidance, cell-cell adhesion, establishment of nucleus localization, inner ear morphogenesis, mammary gland duct morphogenesis, negative regulation of axon extension, neuron migration, positive regulation of axon extension, positive regulation of cell proliferation, regulation of cell migration basement membrane, cytoplasm, extracellular region protein binding Human NTN3 Reactome UniProtKB {GO:0042692=Reactome:REACT_21303, GO:0003674=GO_REF:0000015, GO:0051149=Reactome:REACT_21402, GO:0005794=GO_REF:0000019, GO:0007411=PMID:9143507, GO:0005578=GO_REF:0000039, GO:0005102=GO_REF:0000019, GO:0005575=GO_REF:0000015} O00634 Netrin-3 protein 20091029 {GO:0042692=TAS, GO:0003674=ND, GO:0051149=TAS, GO:0005794=IEA, GO:0007411=NAS, GO:0005578=IEA, GO:0005102=IEA, GO:0005575=ND} axon guidance, muscle cell differentiation, positive regulation of muscle cell differentiation Golgi apparatus, cellular_component, proteinaceous extracellular matrix molecular_function, receptor binding Human NTN4 Reactome UniProtKB {GO:0016322=GO_REF:0000019, GO:0060668=GO_REF:0000019, GO:0005886=Reactome:REACT_22282, GO:0007411=Reactome:REACT_18266, GO:0043237=GO_REF:0000019, GO:0005604=GO_REF:0000039} Q9HB63 Netrin-4 protein 20121102 {GO:0016322=IEA, GO:0060668=IEA, GO:0005886=TAS, GO:0007411=TAS, GO:0043237=IEA, GO:0005604=IEA} axon guidance, neuron remodeling, regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling basement membrane, plasma membrane laminin-1 binding Human NTNG1 UniProtKB UniProtKB {GO:0005515=PMID:14595443, GO:0007409=GO_REF:0000024, GO:0046658=GO_REF:0000024} Q9Y2I2 Netrin-G1 protein 20041006 {GO:0005515=IPI, GO:0007409=ISS, GO:0046658=ISS} axonogenesis anchored to plasma membrane protein binding Human UniProtKB:Q8R4G0 NTNG2 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0007409=GO_REF:0000024, GO:0046658=GO_REF:0000024} Q96CW9 Netrin-G2 protein 20061026 {GO:0003674=ND, GO:0007409=ISS, GO:0046658=ISS} axonogenesis anchored to plasma membrane molecular_function Human NTPCR UniProtKB UniProtKB {GO:0017111=GO_REF:0000003, GO:0005524=GO_REF:0000037, GO:0019204=GO_REF:0000002, GO:0016740=GO_REF:0000002} Q9BSD7 Cancer-related nucleoside-triphosphatase protein 20130413 {GO:0017111=IEA, GO:0005524=IEA, GO:0019204=IEA, GO:0016740=IEA} ATP binding, nucleoside-triphosphatase activity, nucleotide phosphatase activity, transferase activity Human EC:3.6.1.15 NTRK1 Reactome UniProtKB {GO:0005515=PMID:15488758, GO:0021553=GO_REF:0000019, GO:0010465=PMID:15488758, GO:0046579=PMID:15488758, GO:0048678=GO_REF:0000019, GO:0042803=PMID:17196528, GO:0043524=GO_REF:0000024, GO:0043068=GO_REF:0000024, GO:0060009=GO_REF:0000019, GO:0046777=PMID:15488758, GO:0007411=GO_REF:0000019, GO:0051602=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0007611=GO_REF:0000019, GO:0031667=GO_REF:0000019, GO:0070374=PMID:15488758, GO:0005166=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0048406=PMID:15488758, GO:0007568=GO_REF:0000019, GO:0051968=GO_REF:0000019, GO:0071316=GO_REF:0000019, GO:0048485=GO_REF:0000024, GO:0005030=GO_REF:0000002, GO:0046875=GO_REF:0000019, GO:0032320=PMID:15488758, GO:0005887=PMID:15488758, GO:0051599=GO_REF:0000019, GO:0060385=GO_REF:0000024, GO:0010976=PMID:15488758, GO:0030424=GO_REF:0000019, GO:0008285=PMID:15488758, GO:0005886=Reactome:REACT_12385, GO:0007264=Reactome:REACT_12077, GO:0045471=GO_REF:0000019, GO:0007265=Reactome:REACT_12033, GO:0007202=Reactome:REACT_12079, GO:0030425=GO_REF:0000019, GO:0007190=Reactome:REACT_11046, GO:0000186=Reactome:REACT_12005, GO:0051092=PMID:15488758, GO:0030183=GO_REF:0000019, GO:0050966=GO_REF:0000019, GO:0050965=GO_REF:0000019, GO:0009314=GO_REF:0000019, GO:0014823=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0042490=GO_REF:0000019, GO:0043121=PMID:9290260, GO:0048015=Reactome:REACT_12464, GO:0042493=GO_REF:0000019, GO:0031410=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0031901=GO_REF:0000039, GO:0006468=PMID:15488758, GO:0004714=PMID:15488758, GO:0007169=Reactome:REACT_11064, GO:0010623=GO_REF:0000024, GO:0005768=Reactome:REACT_10033} P04629 High affinity nerve growth factor receptor protein 20061214 {GO:0005515=IPI, GO:0021553=IEA, GO:0010465=IDA, GO:0046579=IDA, GO:0048678=IEA, GO:0042803=IDA, GO:0043524=ISS, GO:0043068=ISS, GO:0060009=IEA, GO:0046777=IDA, GO:0007411=IEA, GO:0051602=IEA, GO:0043025=IEA, GO:0007611=IEA, GO:0031667=IEA, GO:0070374=IDA, GO:0005166=IEA, GO:0009986=IEA, GO:0048406=IDA, GO:0007568=IEA, GO:0051968=IEA, GO:0071316=IEA, GO:0048485=ISS, GO:0005030=IEA, GO:0046875=IEA, GO:0032320=IDA, GO:0005887=IDA, GO:0051599=IEA, GO:0060385=ISS, GO:0010976=IDA, GO:0030424=IEA, GO:0008285=IDA, GO:0005886=TAS, GO:0007264=TAS, GO:0045471=IEA, GO:0007265=TAS, GO:0007202=TAS, GO:0030425=IEA, GO:0007190=TAS, GO:0000186=TAS, GO:0051092=IDA, GO:0030183=IEA, GO:0050966=IEA, GO:0050965=IEA, GO:0009314=IEA, GO:0014823=IEA, GO:0048011=TAS, GO:0042490=IEA, GO:0043121=TAS, GO:0048015=TAS, GO:0042493=IEA, GO:0031410=IEA, GO:0005524=IEA, GO:0031901=IEA, GO:0006468=IDA, GO:0004714=IDA, GO:0007169=TAS, GO:0010623=ISS, GO:0005768=TAS} B cell differentiation, Ras protein signal transduction, Sertoli cell development, activation of MAPKK activity, activation of adenylate cyclase activity, activation of phospholipase C activity, aging, axon guidance, axonogenesis involved in innervation, cellular response to nicotine, detection of mechanical stimulus involved in sensory perception of pain, detection of temperature stimulus involved in sensory perception of pain, developmental programmed cell death, learning or memory, mechanoreceptor differentiation, negative regulation of cell proliferation, negative regulation of neuron apoptotic process, neurotrophin TRK receptor signaling pathway, olfactory nerve development, phosphatidylinositol-mediated signaling, positive regulation of ERK1 and ERK2 cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of Ras GTPase activity, positive regulation of Ras protein signal transduction, positive regulation of neuron projection development, positive regulation of programmed cell death, positive regulation of synaptic transmission, glutamatergic, protein autophosphorylation, protein phosphorylation, response to activity, response to axon injury, response to drug, response to electrical stimulus, response to ethanol, response to hydrostatic pressure, response to nutrient levels, response to radiation, small GTPase mediated signal transduction, sympathetic nervous system development, transmembrane receptor protein tyrosine kinase signaling pathway axon, cell surface, cytoplasmic vesicle, dendrite, early endosome membrane, endosome, integral to plasma membrane, neuronal cell body, plasma membrane ATP binding, ephrin receptor binding, nerve growth factor binding, nerve growth factor receptor activity, neurotrophin binding, neurotrophin p75 receptor binding, neurotrophin receptor activity, protein binding, protein homodimerization activity, transmembrane receptor protein tyrosine kinase activity Human NTRK2 Reactome UniProtKB {GO:0035584=GO_REF:0000019, GO:0048709=GO_REF:0000019, GO:0010996=GO_REF:0000019, GO:0060291=GO_REF:0000019, GO:2000811=GO_REF:0000019, GO:0042803=GO_REF:0000024, GO:0043524=GO_REF:0000024, GO:0046777=GO_REF:0000024, GO:0032314=GO_REF:0000024, GO:0043025=GO_REF:0000019, GO:0007612=GO_REF:0000024, GO:0048786=GO_REF:0000019, GO:0048403=GO_REF:0000024, GO:0007616=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0051968=GO_REF:0000019, GO:0046548=GO_REF:0000019, GO:0046928=GO_REF:0000019, GO:0014069=GO_REF:0000019, GO:0014068=GO_REF:0000024, GO:0060076=GO_REF:0000019, GO:0046875=GO_REF:0000019, GO:0005887=PMID:15494731, GO:0010976=GO_REF:0000024, GO:0050773=GO_REF:0000019, GO:0048935=GO_REF:0000019, GO:0060175=PMID:15494731, GO:0050772=GO_REF:0000024, GO:0010008=GO_REF:0000039, GO:0007631=GO_REF:0000019, GO:0008284=GO_REF:0000024, GO:0021987=GO_REF:0000024, GO:0051896=GO_REF:0000019, GO:0031547=PMID:15494731, GO:0005829=GO_REF:0000019, GO:0030426=GO_REF:0000019, GO:0007190=Reactome:REACT_11046, GO:0043195=GO_REF:0000019, GO:0030182=GO_REF:0000024, GO:0048011=Reactome:REACT_11061, GO:0042490=GO_REF:0000019, GO:0043121=GO_REF:0000024, GO:0021954=GO_REF:0000024, GO:0014047=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0010628=GO_REF:0000024, GO:0043410=GO_REF:0000024, GO:0001764=GO_REF:0000024, GO:0001570=GO_REF:0000019, GO:0007169=Reactome:REACT_11064} Q16620 BDNF/NT-3 growth factors receptor protein 20130301 {GO:0035584=IEA, GO:0048709=IEA, GO:0010996=IEA, GO:0060291=IEA, GO:2000811=IEA, GO:0042803=ISS, GO:0043524=ISS, GO:0046777=ISS, GO:0032314=ISS, GO:0043025=IEA, GO:0007612=ISS, GO:0048786=IEA, GO:0048403=ISS, GO:0007616=IEA, GO:0009986=IEA, GO:0007568=IEA, GO:0051968=IEA, GO:0046548=IEA, GO:0046928=IEA, GO:0014069=IEA, GO:0014068=ISS, GO:0060076=IEA, GO:0046875=IEA, GO:0005887=IDA, GO:0010976=ISS, GO:0050773=IEA, GO:0048935=IEA, GO:0060175=IMP, GO:0050772=ISS, GO:0010008=IEA, GO:0007631=IEA, GO:0008284=ISS, GO:0021987=ISS, GO:0051896=IEA, GO:0031547=IMP, GO:0005829=IEA, GO:0030426=IEA, GO:0007190=TAS, GO:0043195=IEA, GO:0030182=ISS, GO:0048011=TAS, GO:0042490=IEA, GO:0043121=ISS, GO:0021954=ISS, GO:0014047=IEA, GO:0005524=IEA, GO:0010628=ISS, GO:0043410=ISS, GO:0001764=ISS, GO:0001570=IEA, GO:0007169=TAS} activation of adenylate cyclase activity, aging, brain-derived neurotrophic factor receptor signaling pathway, calcium-mediated signaling using intracellular calcium source, central nervous system neuron development, cerebral cortex development, feeding behavior, glutamate secretion, learning, long-term memory, long-term synaptic potentiation, mechanoreceptor differentiation, negative regulation of anoikis, negative regulation of neuron apoptotic process, neuron differentiation, neuron migration, neurotrophin TRK receptor signaling pathway, oligodendrocyte differentiation, peripheral nervous system neuron development, positive regulation of MAPK cascade, positive regulation of axonogenesis, positive regulation of cell proliferation, positive regulation of gene expression, positive regulation of neuron projection development, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of synaptic transmission, glutamatergic, protein autophosphorylation, regulation of Rac GTPase activity, regulation of dendrite development, regulation of neurotransmitter secretion, regulation of protein kinase B signaling cascade, response to auditory stimulus, retinal rod cell development, transmembrane receptor protein tyrosine kinase signaling pathway, vasculogenesis cell surface, cytosol, endosome membrane, excitatory synapse, growth cone, integral to plasma membrane, neuronal cell body, postsynaptic density, presynaptic active zone, terminal bouton ATP binding, brain-derived neurotrophic factor binding, brain-derived neurotrophic factor-activated receptor activity, ephrin receptor binding, neurotrophin binding, protein homodimerization activity Human NTRK3 GOC UniProtKB {GO:0008284=PMID:23027130, GO:0032856=PMID:23027130, GO:0071300=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0019056=GO_REF:0000019, GO:0038179=PMID:23027130, GO:2000251=PMID:23027130, GO:0048678=GO_REF:0000019, GO:0050927=PMID:23027130, GO:0000187=PMID:23027130, GO:0002039=PMID:23027130, GO:0033138=PMID:23027130, GO:0005737=GO_REF:0000019, GO:0046777=GO_REF:0000019, GO:0032148=PMID:23027130, GO:0060548=GO_REF:0000019, GO:0090102=GO_REF:0000019, GO:0051412=GO_REF:0000019, GO:0042490=GO_REF:0000019, GO:0030335=PMID:23027130, GO:0043121=PMID:7806211, GO:0048665=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0010628=PMID:23027130, GO:0048712=GO_REF:0000019, GO:0005030=PMID:23027130, GO:0046875=GO_REF:0000019, GO:0005887=GO_REF:0000002, GO:0048691=GO_REF:0000019, GO:0001933=PMID:23027130, GO:0001764=GO_REF:0000019, GO:0004714=GO_REF:0000003, GO:0007169=PMID:23027130} Q16288 NT-3 growth factor receptor protein 20130413 {GO:0008284=IDA, GO:0032856=IDA, GO:0071300=IEA, GO:0045471=IEA, GO:0019056=IEA, GO:0038179=IDA, GO:2000251=IDA, GO:0048678=IEA, GO:0050927=IDA, GO:0000187=IDA, GO:0002039=IPI, GO:0033138=IDA, GO:0005737=IEA, GO:0046777=IEA, GO:0032148=IDA, GO:0060548=IEA, GO:0090102=IEA, GO:0051412=IEA, GO:0042490=IEA, GO:0030335=IDA, GO:0043121=TAS, GO:0048665=IEA, GO:0005524=IEA, GO:0010628=IDA, GO:0048712=IEA, GO:0005030=IDA, GO:0046875=IEA, GO:0005887=IEA, GO:0048691=IEA, GO:0001933=IDA, GO:0001764=IEA, GO:0004714=IEA, GO:0007169=IDA} activation of MAPK activity, activation of Ras GTPase activity, activation of protein kinase B activity, cellular response to retinoic acid, cochlea development, mechanoreceptor differentiation, modulation by virus of host transcription, negative regulation of astrocyte differentiation, negative regulation of cell death, negative regulation of protein phosphorylation, neuron fate specification, neuron migration, neurotrophin signaling pathway, positive regulation of actin cytoskeleton reorganization, positive regulation of axon extension involved in regeneration, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of gene expression, positive regulation of peptidyl-serine phosphorylation, positive regulation of positive chemotaxis, protein autophosphorylation, response to axon injury, response to corticosterone stimulus, response to ethanol, transmembrane receptor protein tyrosine kinase signaling pathway cytoplasm, integral to plasma membrane ATP binding, ephrin receptor binding, neurotrophin binding, neurotrophin receptor activity, p53 binding, transmembrane receptor protein tyrosine kinase activity Human NTS Reactome UniProtKB {GO:0030133=GO_REF:0000039, GO:0007165=PMID:8954810, GO:0050880=GO_REF:0000037, GO:0005576=Reactome:REACT_22436, GO:0005184=GO_REF:0000002} P30990 Neurotensin/neuromedin N protein 20081217 {GO:0030133=IEA, GO:0007165=NAS, GO:0050880=IEA, GO:0005576=TAS, GO:0005184=IEA} regulation of blood vessel size, signal transduction extracellular region, transport vesicle neuropeptide hormone activity Human NTSR1 Reactome UniProtKB {GO:0008344=GO_REF:0000019, GO:0005794=PMID:9763490, GO:0005886=Reactome:REACT_22436, GO:0007186=PMID:8381365, GO:0005887=PMID:8381365, GO:0004930=PMID:8381365, GO:0005783=PMID:9763490, GO:0007268=PMID:9763490, GO:0016492=GO_REF:0000002} P30989 Neurotensin receptor type 1 protein 20081217 {GO:0008344=IEA, GO:0005794=TAS, GO:0005886=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0004930=TAS, GO:0005783=TAS, GO:0007268=TAS, GO:0016492=IEA} G-protein coupled receptor signaling pathway, adult locomotory behavior, synaptic transmission Golgi apparatus, endoplasmic reticulum, integral to plasma membrane, plasma membrane G-protein coupled neurotensin receptor activity, G-protein coupled receptor activity Human NTSR2 Reactome UniProtKB {GO:0005886=Reactome:REACT_22436, GO:0005887=PMID:9851594, GO:0004930=PMID:9851594, GO:0042391=GO_REF:0000019, GO:0007200=GO_REF:0000019, GO:0016492=GO_REF:0000019, GO:0007600=PMID:8795617, GO:0007166=PMID:9851594} O95665 Neurotensin receptor type 2 protein 20081217 {GO:0005886=TAS, GO:0005887=TAS, GO:0004930=TAS, GO:0042391=IEA, GO:0007200=IEA, GO:0016492=IEA, GO:0007600=TAS, GO:0007166=TAS} cell surface receptor signaling pathway, phospholipase C-activating G-protein coupled receptor signaling pathway, regulation of membrane potential, sensory perception integral to plasma membrane, plasma membrane G-protein coupled neurotensin receptor activity, G-protein coupled receptor activity Human NUAK1 UniProtKB UniProtKB {GO:0005515=PMID:20354225, GO:0035507=PMID:20354225, GO:0005634=PMID:21317932, GO:0005524=GO_REF:0000037, GO:0030155=PMID:20354225, GO:0006974=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0002039=PMID:21317932, GO:0005737=PMID:21317932, GO:0004674=PMID:20354225, GO:0042127=PMID:21317932, GO:0007155=GO_REF:0000037, GO:2000772=PMID:19927127, GO:0016772=GO_REF:0000002} O60285 NUAK family SNF1-like kinase 1 protein 20110722 {GO:0005515=IPI, GO:0035507=IDA, GO:0005634=IDA, GO:0005524=IEA, GO:0030155=IDA, GO:0006974=IEA, GO:0046872=IEA, GO:0002039=IPI, GO:0005737=IDA, GO:0004674=IDA, GO:0042127=TAS, GO:0007155=IEA, GO:2000772=IDA, GO:0016772=IEA} cell adhesion, regulation of cell adhesion, regulation of cell proliferation, regulation of cellular senescence, regulation of myosin-light-chain-phosphatase activity, response to DNA damage stimulus cytoplasm, nucleus ATP binding, metal ion binding, p53 binding, protein binding, protein serine/threonine kinase activity, transferase activity, transferring phosphorus-containing groups Human UniProtKB:P62140 NUAK2 UniProtKB UniProtKB {GO:0005515=PMID:19927127, GO:0043066=PMID:15345718, GO:0030036=PMID:14575707, GO:0000287=PMID:14976552, GO:0004674=PMID:19927127, GO:0006915=GO_REF:0000037, GO:0006468=PMID:14976552, GO:0042149=PMID:14575707, GO:0005524=PMID:14976552} Q9H093 NUAK family SNF1-like kinase 2 protein 20110722 {GO:0005515=IPI, GO:0043066=IDA, GO:0030036=IDA, GO:0000287=IDA, GO:0004674=IDA, GO:0006915=IEA, GO:0006468=IDA, GO:0042149=IDA, GO:0005524=IDA} actin cytoskeleton organization, apoptotic process, cellular response to glucose starvation, negative regulation of apoptotic process, protein phosphorylation ATP binding, magnesium ion binding, protein binding, protein serine/threonine kinase activity Human NUB1 UniProtKB UniProtKB {GO:0005515=PMID:16707496, GO:0006511=PMID:16707496, GO:0016567=PMID:16707496, GO:0032436=PMID:16707496, GO:0034612=PMID:16707496, GO:0005634=GO_REF:0000039, GO:0034341=PMID:16707496} Q9Y5A7 NEDD8 ultimate buster 1 protein 20100728 {GO:0005515=IPI, GO:0006511=IMP, GO:0016567=IMP, GO:0032436=IMP, GO:0034612=IEP, GO:0005634=IEA, GO:0034341=IEP} positive regulation of proteasomal ubiquitin-dependent protein catabolic process, protein ubiquitination, response to interferon-gamma, response to tumor necrosis factor, ubiquitin-dependent protein catabolic process nucleus protein binding Human NUBP1 HPA UniProtKB {GO:0005515=PMID:18573874, GO:0017111=GO_REF:0000002, GO:0051539=GO_REF:0000037, GO:0005886=GO_REF:0000052, GO:0016226=PMID:18573874, GO:0051536=PMID:18573874, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0005829=PMID:18573874, GO:0006879=PMID:18573874, GO:0005737=GO_REF:0000052, GO:0000166=PMID:7926816, GO:0016049=PMID:18573874} P53384 Cytosolic Fe-S cluster assembly factor NUBP1 protein 20111111 {GO:0005515=IPI, GO:0017111=IEA, GO:0051539=IEA, GO:0005886=IDA, GO:0016226=IMP, GO:0051536=IDA, GO:0044281=TAS, GO:0005524=IEA, GO:0046872=IEA, GO:0005829=IDA, GO:0006879=IMP, GO:0005737=IDA, GO:0000166=TAS, GO:0016049=IMP} cell growth, cellular iron ion homeostasis, iron-sulfur cluster assembly, small molecule metabolic process cytoplasm, cytosol, plasma membrane 4 iron, 4 sulfur cluster binding, ATP binding, iron-sulfur cluster binding, metal ion binding, nucleoside-triphosphatase activity, nucleotide binding, protein binding Human NUBP2 Reactome UniProtKB {GO:0005515=PMID:18573874, GO:0005737=GO_REF:0000037, GO:0051539=GO_REF:0000037, GO:0000166=PMID:10486206, GO:0005815=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q9Y5Y2 Cytosolic Fe-S cluster assembly factor NUBP2 protein 20121107 {GO:0005515=IPI, GO:0005737=IEA, GO:0051539=IEA, GO:0000166=TAS, GO:0005815=IEA, GO:0005634=IEA, GO:0044281=TAS, GO:0005524=IEA, GO:0046872=IEA} small molecule metabolic process cytoplasm, microtubule organizing center, nucleus 4 iron, 4 sulfur cluster binding, ATP binding, metal ion binding, nucleotide binding, protein binding Human NUCB1 HPA UniProtKB {GO:0005793=PMID:15308636, GO:0005794=GO_REF:0000052, GO:0016020=GO_REF:0000037, GO:0015630=GO_REF:0000052, GO:0005509=GO_REF:0000002, GO:0005615=PMID:1520323, GO:0003677=GO_REF:0000037} Q02818 Nucleobindin-1 protein 20080818 {GO:0005793=IDA, GO:0005794=IDA, GO:0016020=IEA, GO:0015630=IDA, GO:0005509=IEA, GO:0005615=TAS, GO:0003677=IEA} Golgi apparatus, endoplasmic reticulum-Golgi intermediate compartment, extracellular space, membrane, microtubule cytoskeleton DNA binding, calcium ion binding Human NUCB2 HPA UniProtKB {GO:0005515=PMID:21988832, GO:0005640=GO_REF:0000019, GO:0005793=PMID:15308636, GO:0005794=GO_REF:0000052, GO:0005886=PMID:7811391, GO:0005783=GO_REF:0000039, GO:0005509=GO_REF:0000019, GO:0005615=PMID:7811391, GO:0003677=GO_REF:0000037, GO:0005829=PMID:7811391} P80303 Nucleobindin-2 protein 20101115 {GO:0005515=IPI, GO:0005640=IEA, GO:0005793=IDA, GO:0005794=IDA, GO:0005886=TAS, GO:0005783=IEA, GO:0005509=IEA, GO:0005615=TAS, GO:0003677=IEA, GO:0005829=TAS} Golgi apparatus, cytosol, endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment, extracellular space, nuclear outer membrane, plasma membrane DNA binding, calcium ion binding, protein binding Human NUCKS1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000019, GO:0005634=GO_REF:0000039} Q9H1E3 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 protein 20130413 {GO:0005737=IEA, GO:0005634=IEA} cytoplasm, nucleus Human UniProtKB-SubCell:SL-0191 NUDC HPA UniProtKB {GO:0000910=Reactome:REACT_1932, GO:0000236=Reactome:REACT_682, GO:0005737=GO_REF:0000052, GO:0008283=PMID:10210332, GO:0000087=Reactome:REACT_910, GO:0005874=GO_REF:0000037, GO:0005654=Reactome:REACT_1326, GO:0007275=PMID:10210332, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0005829=Reactome:REACT_150414} Q9Y266 Nuclear migration protein nudC protein 20100326 {GO:0000910=TAS, GO:0000236=TAS, GO:0005737=IDA, GO:0008283=TAS, GO:0000087=TAS, GO:0005874=IEA, GO:0005654=TAS, GO:0007275=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0005829=TAS} M phase of mitotic cell cycle, cell proliferation, cytokinesis, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, multicellular organismal development cytoplasm, cytosol, microtubule, nucleoplasm Human NUDCD1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039} Q96RS6 NudC domain-containing protein 1 protein 20130413 {GO:0005737=IEA, GO:0005634=IEA} cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 NUDCD2 LIFEdb UniProtKB {GO:0005622=GO_REF:0000054, GO:0000922=GO_REF:0000039, GO:0005737=GO_REF:0000037, GO:0005815=GO_REF:0000039, GO:0000777=GO_REF:0000039} Q8WVJ2 NudC domain-containing protein 2 protein 20100607 {GO:0005622=IDA, GO:0000922=IEA, GO:0005737=IEA, GO:0005815=IEA, GO:0000777=IEA} condensed chromosome kinetochore, cytoplasm, intracellular, microtubule organizing center, spindle pole Human NUDCD3 null null {} null null null null {} null null null NUDT1 HPA UniProtKB {GO:0006203=PMID:22556419, GO:0006200=PMID:11139615, GO:0003924=PMID:7713500, GO:0055086=Reactome:REACT_1698, GO:0005634=PMID:12857738, GO:0044281=Reactome:REACT_111217, GO:0050072=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_150363, GO:0006184=PMID:22556419, GO:0035539=PMID:22556419, GO:0006195=PMID:10608900, GO:0005737=GO_REF:0000052, GO:0030515=GO_REF:0000024, GO:0006281=GO_REF:0000002, GO:0034656=Reactome:REACT_150237, GO:0005759=PMID:7782328, GO:0042262=PMID:10608900, GO:0006979=PMID:8226881, GO:0008413=PMID:22556419, GO:0047693=PMID:11139615} P36639 7,8-dihydro-8-oxoguanine triphosphatase protein 20081203 {GO:0006203=IDA, GO:0006200=IDA, GO:0003924=TAS, GO:0055086=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0050072=ISS, GO:0046872=IEA, GO:0005829=TAS, GO:0006184=IDA, GO:0035539=IDA, GO:0006195=IDA, GO:0005737=IDA, GO:0030515=ISS, GO:0006281=IEA, GO:0034656=TAS, GO:0005759=IDA, GO:0042262=IDA, GO:0006979=TAS, GO:0008413=IDA, GO:0047693=IDA} ATP catabolic process, DNA protection, DNA repair, GTP catabolic process, dGTP catabolic process, nucleobase-containing small molecule catabolic process, nucleobase-containing small molecule metabolic process, purine nucleotide catabolic process, response to oxidative stress, small molecule metabolic process cytoplasm, cytosol, mitochondrial matrix, nucleus 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity, 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity, ATP diphosphatase activity, GTPase activity, m7G(5')pppN diphosphatase activity, metal ion binding, snoRNA binding Human NUDT10 Reactome UniProtKB {GO:0052846=GO_REF:0000003, GO:0052845=GO_REF:0000003, GO:0052844=GO_REF:0000003, GO:0052843=GO_REF:0000003, GO:0043647=Reactome:REACT_150188, GO:0008486=GO_REF:0000024, GO:0052848=GO_REF:0000003, GO:0052847=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0052840=GO_REF:0000003, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_150467} Q8NFP7 Diphosphoinositol polyphosphate phosphohydrolase 3-alpha protein 20111102 {GO:0052846=IEA, GO:0052845=IEA, GO:0052844=IEA, GO:0052843=IEA, GO:0043647=TAS, GO:0008486=ISS, GO:0052848=IEA, GO:0052847=IEA, GO:0044281=TAS, GO:0052840=IEA, GO:0046872=IEA, GO:0005829=TAS} inositol phosphate metabolic process, small molecule metabolic process cytosol diphosphoinositol-polyphosphate diphosphatase activity, inositol diphosphate tetrakisphosphate diphosphatase activity, inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity, inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity, inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity, inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity, inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity, inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity, metal ion binding Human NUDT11 LIFEdb UniProtKB {GO:0052846=GO_REF:0000003, GO:0052845=GO_REF:0000003, GO:0052844=GO_REF:0000003, GO:0052843=GO_REF:0000003, GO:0043647=Reactome:REACT_150188, GO:0008486=GO_REF:0000024, GO:0052848=GO_REF:0000003, GO:0052847=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0052840=GO_REF:0000003, GO:0005829=Reactome:REACT_150467, GO:0005622=GO_REF:0000054} Q96G61 Diphosphoinositol polyphosphate phosphohydrolase 3-beta protein 20100607 {GO:0052846=IEA, GO:0052845=IEA, GO:0052844=IEA, GO:0052843=IEA, GO:0043647=TAS, GO:0008486=ISS, GO:0052848=IEA, GO:0052847=IEA, GO:0044281=TAS, GO:0046872=IEA, GO:0052840=IEA, GO:0005829=TAS, GO:0005622=IDA} inositol phosphate metabolic process, small molecule metabolic process cytosol, intracellular diphosphoinositol-polyphosphate diphosphatase activity, inositol diphosphate tetrakisphosphate diphosphatase activity, inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity, inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity, inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity, inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity, inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity, inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity, metal ion binding Human NUDT13 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0016787=GO_REF:0000037, GO:0046872=GO_REF:0000002} Q86X67 Nucleoside diphosphate-linked moiety X motif 13 protein 20130413 {GO:0005739=IEA, GO:0016787=IEA, GO:0046872=IEA} mitochondrion hydrolase activity, metal ion binding Human Ensembl:ENSMUSP00000022343 NUDT14 IntAct UniProtKB {GO:0005515=PMID:12620389, GO:0005737=GO_REF:0000039, GO:0047631=GO_REF:0000019, GO:0008768=GO_REF:0000003, GO:0046872=GO_REF:0000002} O95848 Uridine diphosphate glucose pyrophosphatase protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0047631=IEA, GO:0008768=IEA, GO:0046872=IEA} cytoplasm ADP-ribose diphosphatase activity, UDP-sugar diphosphatase activity, metal ion binding, protein binding Human UniProtKB:P10398 NUDT15 Reactome UniProtKB {GO:0006184=PMID:22556419, GO:0035539=PMID:22556419, GO:0034656=Reactome:REACT_150237, GO:0006203=PMID:22556419, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0008413=PMID:22556419, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_150452} Q9NV35 Probable 8-oxo-dGTP diphosphatase NUDT15 protein 20130301 {GO:0006184=IDA, GO:0035539=IDA, GO:0034656=TAS, GO:0006203=IDA, GO:0055086=TAS, GO:0044281=TAS, GO:0008413=IDA, GO:0046872=IEA, GO:0005829=TAS} GTP catabolic process, dGTP catabolic process, nucleobase-containing small molecule catabolic process, nucleobase-containing small molecule metabolic process, small molecule metabolic process cytosol 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity, 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity, metal ion binding Human NUDT16L1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0030515=PMID:21070968, GO:0016787=GO_REF:0000002, GO:0050072=GO_REF:0000024, GO:0042803=PMID:18820299} Q9BRJ7 Protein syndesmos protein 20121116 {GO:0005737=IEA, GO:0030515=IDA, GO:0016787=IEA, GO:0050072=ISS, GO:0042803=IDA} cytoplasm hydrolase activity, m7G(5')pppN diphosphatase activity, protein homodimerization activity, snoRNA binding NOT Human UniProtKB:Q8VHN8 NUDT18 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0046712=PMID:22556419, GO:0000287=PMID:22556419, GO:0046057=PMID:22556419, GO:0046067=PMID:22556419, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_150427, GO:0034656=Reactome:REACT_150237, GO:0016787=GO_REF:0000038, GO:0044715=PMID:22556419, GO:0044716=PMID:22556419, GO:0044717=PMID:22556419} Q6ZVK8 8-oxo-dGDP phosphatase NUDT18 protein 20130415 {GO:0005515=IPI, GO:0046712=IDA, GO:0000287=IDA, GO:0046057=IDA, GO:0046067=IDA, GO:0055086=TAS, GO:0044281=TAS, GO:0005829=TAS, GO:0034656=TAS, GO:0016787=IEA, GO:0044715=IDA, GO:0044716=IDA, GO:0044717=IDA} GDP catabolic process, dADP catabolic process, dGDP catabolic process, nucleobase-containing small molecule catabolic process, nucleobase-containing small molecule metabolic process, small molecule metabolic process cytosol 8-hydroxy-dADP phosphatase activity, 8-oxo-GDP phosphatase activity, 8-oxo-dGDP phosphatase activity, hydrolase activity, magnesium ion binding, protein binding Human UniProtKB:Q9UI14 NUDT19 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0008150=GO_REF:0000015, GO:0016787=GO_REF:0000037, GO:0005102=PMID:20178365, GO:0005575=GO_REF:0000015, GO:0046872=GO_REF:0000037, GO:0005777=GO_REF:0000039} A8MXV4 Nucleoside diphosphate-linked moiety X motif 19, mitochondrial protein 20120517 {GO:0005739=IEA, GO:0008150=ND, GO:0016787=IEA, GO:0005102=IPI, GO:0005575=ND, GO:0046872=IEA, GO:0005777=IEA} biological_process cellular_component, mitochondrion, peroxisome hydrolase activity, metal ion binding, receptor binding Human NUDT2 PINC UniProtKB {GO:0005739=GO_REF:0000019, GO:0008803=PMID:7487923, GO:0006139=PMID:7487923, GO:0004081=PMID:11738085, GO:0006917=PMID:10452553, GO:0005525=GO_REF:0000037} P50583 "Bis(5'-nucleosyl)-tetraphosphatase ""asymmetrical""" protein 20030904 {GO:0005739=IEA, GO:0008803=TAS, GO:0006139=TAS, GO:0004081=ISS, GO:0006917=ISS, GO:0005525=IEA} induction of apoptosis, nucleobase-containing compound metabolic process mitochondrion GTP binding, bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity, bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity Human NUDT21 LIFEdb UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0006397=PMID:8626397, GO:0005515=PMID:16713569, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0006378=PMID:20695905, GO:0005813=GO_REF:0000054, GO:0051262=PMID:21295486, GO:0006366=Reactome:REACT_1366, GO:0042826=PMID:17172643, GO:0003723=PMID:8626397, GO:0031124=Reactome:REACT_1849, GO:0005634=PMID:20695905, GO:0003729=PMID:21295486, GO:0042803=PMID:20479262, GO:0042382=PMID:15169763, GO:0016787=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0017091=PMID:20479262, GO:0005654=Reactome:REACT_1935, GO:0005849=PMID:20695905} O43809 Cleavage and polyadenylation specificity factor subunit 5 protein 20100607 {GO:0008380=TAS, GO:0006397=IDA, GO:0005515=IPI, GO:0010467=TAS, GO:0006369=TAS, GO:0006378=IMP, GO:0005813=IDA, GO:0051262=IDA, GO:0006366=TAS, GO:0042826=IPI, GO:0003723=IDA, GO:0031124=TAS, GO:0005634=IDA, GO:0003729=IDA, GO:0042803=IPI, GO:0042382=IDA, GO:0016787=IEA, GO:0000398=TAS, GO:0017091=IDA, GO:0005654=TAS, GO:0005849=IDA} RNA splicing, gene expression, mRNA 3'-end processing, mRNA polyadenylation, mRNA processing, mRNA splicing, via spliceosome, protein tetramerization, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter centrosome, mRNA cleavage factor complex, nucleoplasm, nucleus, paraspeckles AU-rich element binding, RNA binding, histone deacetylase binding, hydrolase activity, mRNA binding, protein binding, protein homodimerization activity Human NUDT22 InterPro UniProtKB {GO:0016787=GO_REF:0000002} Q9BRQ3 Nucleoside diphosphate-linked moiety X motif 22 protein 20130413 {GO:0016787=IEA} hydrolase activity Human InterPro:IPR000086 NUDT3 Reactome UniProtKB {GO:0052846=GO_REF:0000003, GO:0052845=GO_REF:0000003, GO:0052844=GO_REF:0000003, GO:0052843=GO_REF:0000003, GO:0000287=PMID:19585659, GO:0043647=Reactome:REACT_150188, GO:0008486=PMID:10585413, GO:0052848=GO_REF:0000003, GO:0052847=GO_REF:0000003, GO:0007267=PMID:10419486, GO:0044281=Reactome:REACT_111217, GO:0052840=GO_REF:0000003, GO:0005829=Reactome:REACT_150467, GO:0015961=PMID:10419486, GO:0071544=PMID:10585413} O95989 Diphosphoinositol polyphosphate phosphohydrolase 1 protein 20111102 {GO:0052846=IEA, GO:0052845=IEA, GO:0052844=IEA, GO:0052843=IEA, GO:0000287=IDA, GO:0043647=TAS, GO:0008486=IDA, GO:0052848=IEA, GO:0052847=IEA, GO:0007267=TAS, GO:0044281=TAS, GO:0052840=IEA, GO:0005829=TAS, GO:0015961=TAS, GO:0071544=IDA} cell-cell signaling, diadenosine polyphosphate catabolic process, diphosphoinositol polyphosphate catabolic process, inositol phosphate metabolic process, small molecule metabolic process cytosol diphosphoinositol-polyphosphate diphosphatase activity, inositol diphosphate tetrakisphosphate diphosphatase activity, inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity, inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity, inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity, inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity, inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity, inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity, magnesium ion binding Human NUDT5 Reactome UniProtKB {GO:0017110=GO_REF:0000019, GO:0000287=PMID:18462755, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0050072=GO_REF:0000024, GO:0005829=Reactome:REACT_150191, GO:0005622=PMID:10567213, GO:0019303=PMID:10567213, GO:0030515=GO_REF:0000024, GO:0034656=Reactome:REACT_150237, GO:0047631=Reactome:REACT_150191, GO:0016787=GO_REF:0000038, GO:0019144=PMID:18462755, GO:0009117=PMID:10567213, GO:0009191=PMID:18462755} Q9UKK9 ADP-sugar pyrophosphatase protein 20130213 {GO:0017110=IEA, GO:0000287=IDA, GO:0055086=TAS, GO:0044281=TAS, GO:0050072=ISS, GO:0005829=TAS, GO:0005622=NAS, GO:0019303=NAS, GO:0030515=ISS, GO:0034656=TAS, GO:0047631=EXP, GO:0016787=IEA, GO:0019144=IDA, GO:0009117=NAS, GO:0009191=IDA} D-ribose catabolic process, nucleobase-containing small molecule catabolic process, nucleobase-containing small molecule metabolic process, nucleotide metabolic process, ribonucleoside diphosphate catabolic process, small molecule metabolic process cytosol, intracellular ADP-ribose diphosphatase activity, ADP-sugar diphosphatase activity, hydrolase activity, m7G(5')pppN diphosphatase activity, magnesium ion binding, nucleoside-diphosphatase activity, snoRNA binding Human NUDT6 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0008150=GO_REF:0000015, GO:0016787=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0008083=PMID:7984147} P53370 Nucleoside diphosphate-linked moiety X motif 6 protein 20061026 {GO:0005739=IEA, GO:0008150=ND, GO:0016787=IEA, GO:0005634=IEA, GO:0005575=ND, GO:0008083=TAS} biological_process cellular_component, mitochondrion, nucleus growth factor activity, hydrolase activity Human NUDT7 UniProtKB UniProtKB {GO:0000287=GO_REF:0000002, GO:0030145=GO_REF:0000002, GO:0015938=GO_REF:0000024, GO:0009132=GO_REF:0000002, GO:0005102=PMID:20178365, GO:0016818=GO_REF:0000002, GO:0050072=GO_REF:0000024, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0030515=GO_REF:0000024, GO:0016787=GO_REF:0000002, GO:0050873=GO_REF:0000019, GO:0003986=GO_REF:0000024, GO:0046356=GO_REF:0000024, GO:0005777=GO_REF:0000024} P0C024 Peroxisomal coenzyme A diphosphatase NUDT7 protein 20120517 {GO:0000287=IEA, GO:0030145=IEA, GO:0015938=ISS, GO:0009132=IEA, GO:0005102=IPI, GO:0016818=IEA, GO:0050072=ISS, GO:0003674=ND, GO:0008150=ND, GO:0030515=ISS, GO:0016787=IEA, GO:0050873=IEA, GO:0003986=ISS, GO:0046356=ISS, GO:0005777=ISS} acetyl-CoA catabolic process, biological_process, brown fat cell differentiation, coenzyme A catabolic process, nucleoside diphosphate metabolic process peroxisome acetyl-CoA hydrolase activity, hydrolase activity, hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, m7G(5')pppN diphosphatase activity, magnesium ion binding, manganese ion binding, molecular_function, receptor binding, snoRNA binding Human NUDT9 Reactome UniProtKB {GO:0005622=PMID:11385575, GO:0034656=Reactome:REACT_150237, GO:0047631=Reactome:REACT_150155, GO:0016787=GO_REF:0000002, GO:0046032=GO_REF:0000019, GO:0005759=Reactome:REACT_150155, GO:0019144=PMID:11385575, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0043262=GO_REF:0000019, GO:0046709=GO_REF:0000019} Q9BW91 ADP-ribose pyrophosphatase, mitochondrial protein 20130213 {GO:0005622=NAS, GO:0034656=TAS, GO:0047631=EXP, GO:0016787=IEA, GO:0046032=IEA, GO:0005759=TAS, GO:0019144=NAS, GO:0055086=TAS, GO:0044281=TAS, GO:0043262=IEA, GO:0046709=IEA} ADP catabolic process, IDP catabolic process, nucleobase-containing small molecule catabolic process, nucleobase-containing small molecule metabolic process, small molecule metabolic process intracellular, mitochondrial matrix ADP-ribose diphosphatase activity, ADP-sugar diphosphatase activity, adenosine-diphosphatase activity, hydrolase activity Human NUF2 Reactome UniProtKB {GO:0000236=Reactome:REACT_682, GO:0005634=GO_REF:0000039, GO:0005829=Reactome:REACT_150414, GO:0003674=GO_REF:0000015, GO:0007067=GO_REF:0000002, GO:0007059=PMID:11266451, GO:0000087=Reactome:REACT_910, GO:0000777=GO_REF:0000039, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0000775=PMID:11266451, GO:0031262=PMID:14699129, GO:0051301=GO_REF:0000037} Q9BZD4 Kinetochore protein Nuf2 protein 20130213 {GO:0000236=TAS, GO:0005634=IEA, GO:0005829=TAS, GO:0003674=ND, GO:0007067=IEA, GO:0007059=NAS, GO:0000087=TAS, GO:0000777=IEA, GO:0000278=TAS, GO:0000090=TAS, GO:0000775=NAS, GO:0031262=IDA, GO:0051301=IEA} M phase of mitotic cell cycle, cell division, chromosome segregation, mitosis, mitotic anaphase, mitotic cell cycle, mitotic prometaphase Ndc80 complex, chromosome, centromeric region, condensed chromosome kinetochore, cytosol, nucleus molecular_function Human NUFIP1 HPA UniProtKB {GO:0005515=PMID:17636026, GO:0006396=PMID:10556305, GO:0048786=PMID:12941608, GO:0003723=PMID:10556305, GO:0070761=PMID:17636026, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000492=PMID:17636026, GO:0003677=PMID:15107825, GO:0008023=PMID:15107825, GO:0016363=PMID:12941608, GO:0042802=PMID:17636026, GO:0005726=PMID:12941608, GO:0030515=PMID:17636026, GO:0022626=PMID:12941608, GO:0045944=PMID:15107825, GO:0008270=GO_REF:0000002, GO:0030674=PMID:17636026} Q9UHK0 Nuclear fragile X mental retardation-interacting protein 1 protein 20101115 {GO:0005515=IPI, GO:0006396=TAS, GO:0048786=IDA, GO:0003723=IDA, GO:0070761=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0000492=IMP, GO:0003677=NAS, GO:0008023=IDA, GO:0016363=IDA, GO:0042802=IPI, GO:0005726=IDA, GO:0030515=IDA, GO:0022626=IDA, GO:0045944=IMP, GO:0008270=IEA, GO:0030674=IPI} RNA processing, box C/D snoRNP assembly, positive regulation of transcription from RNA polymerase II promoter cytosolic ribosome, nuclear matrix, nucleolus, nucleus, perichromatin fibrils, pre-snoRNP complex, presynaptic active zone, transcription elongation factor complex DNA binding, RNA binding, identical protein binding, protein binding, protein binding, bridging, snoRNA binding, zinc ion binding Human NUFIP2 HGNC UniProtKB {GO:0005515=PMID:16407062, GO:0005737=PMID:12837692, GO:0042788=PMID:12837692, GO:0003723=PMID:12837692, GO:0005634=PMID:12837692} Q7Z417 Nuclear fragile X mental retardation-interacting protein 2 protein 20061204 {GO:0005515=IPI, GO:0005737=IDA, GO:0042788=IDA, GO:0003723=IDA, GO:0005634=IDA} cytoplasm, nucleus, polysomal ribosome RNA binding, protein binding Human NUMA1 HPA UniProtKB {GO:0005515=PMID:15537540, GO:0006997=PMID:1541630, GO:0005694=GO_REF:0000039, GO:0000132=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005819=PMID:7004645, GO:0045177=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0016363=GO_REF:0000039, GO:0005829=Reactome:REACT_15444, GO:0005737=GO_REF:0000052, GO:0000922=PMID:14718566, GO:0005198=PMID:1541630, GO:0000086=Reactome:REACT_2203, GO:0060487=GO_REF:0000019, GO:0005654=Reactome:REACT_15543, GO:0005876=PMID:1541636, GO:0000278=Reactome:REACT_152, GO:0000090=PMID:1541636, GO:0051301=GO_REF:0000037} Q9BTE9 NUMA1 protein protein 20111111 {GO:0005515=IPI, GO:0006997=TAS, GO:0005694=IEA, GO:0000132=IEA, GO:0005730=IDA, GO:0005819=TAS, GO:0045177=IEA, GO:0005634=IDA, GO:0016363=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0000922=IDA, GO:0005198=TAS, GO:0000086=TAS, GO:0060487=IEA, GO:0005654=TAS, GO:0005876=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} G2/M transition of mitotic cell cycle, cell division, establishment of mitotic spindle orientation, lung epithelial cell differentiation, mitotic anaphase, mitotic cell cycle, nucleus organization apical part of cell, chromosome, cytoplasm, cytosol, nuclear matrix, nucleolus, nucleoplasm, nucleus, spindle, spindle microtubule, spindle pole protein binding, structural molecule activity Human NUMB Reactome UniProtKB {GO:0045746=GO_REF:0000019, GO:0045296=GO_REF:0000019, GO:0005886=Reactome:REACT_22358, GO:0008013=GO_REF:0000019, GO:0021849=GO_REF:0000024, GO:0045294=GO_REF:0000019, GO:0045177=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0007409=GO_REF:0000019, GO:0016323=GO_REF:0000019, GO:0007219=Reactome:REACT_118859, GO:0021670=GO_REF:0000024, GO:0007411=Reactome:REACT_18266, GO:0005887=PMID:7596406, GO:0050769=GO_REF:0000024, GO:0060487=GO_REF:0000019, GO:0030862=GO_REF:0000019, GO:0005769=GO_REF:0000019, GO:0019897=GO_REF:0000019, GO:0034332=GO_REF:0000019} P49757 Protein numb homolog protein 20100317 {GO:0045746=IEA, GO:0045296=IEA, GO:0005886=TAS, GO:0008013=IEA, GO:0021849=ISS, GO:0045294=IEA, GO:0045177=IEA, GO:0005634=IEA, GO:0007409=IEA, GO:0016323=IEA, GO:0007219=TAS, GO:0021670=ISS, GO:0007411=TAS, GO:0005887=TAS, GO:0050769=ISS, GO:0060487=IEA, GO:0030862=IEA, GO:0005769=IEA, GO:0019897=IEA, GO:0034332=IEA} Notch signaling pathway, adherens junction organization, axon guidance, axonogenesis, lateral ventricle development, lung epithelial cell differentiation, negative regulation of Notch signaling pathway, neuroblast division in subventricular zone, positive regulation of neurogenesis, positive regulation of polarized epithelial cell differentiation apical part of cell, basolateral plasma membrane, early endosome, extrinsic to plasma membrane, integral to plasma membrane, nucleus, plasma membrane alpha-catenin binding, beta-catenin binding, cadherin binding Human NUMBL IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0005737=GO_REF:0000039, GO:0021849=GO_REF:0000024, GO:0021670=GO_REF:0000024, GO:0050769=GO_REF:0000024, GO:0019221=PMID:18299187, GO:0019538=PMID:20079715, GO:0007399=PMID:9303539} Q9Y6R0 Numb-like protein protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0021849=ISS, GO:0021670=ISS, GO:0050769=ISS, GO:0019221=IDA, GO:0019538=IDA, GO:0007399=TAS} cytokine-mediated signaling pathway, lateral ventricle development, nervous system development, neuroblast division in subventricular zone, positive regulation of neurogenesis, protein metabolic process cytoplasm protein binding Human UniProtKB:Q9NWB1 NUP107 InterPro UniProtKB {GO:0005515=PMID:11564755, GO:0022415=Reactome:REACT_6361, GO:0000236=Reactome:REACT_682, GO:0019221=Reactome:REACT_25229, GO:0044281=Reactome:REACT_111217, GO:0005635=Reactome:REACT_115827, GO:0051292=PMID:15229283, GO:0015031=GO_REF:0000037, GO:0005829=Reactome:REACT_150414, GO:0008645=Reactome:REACT_9441, GO:0006406=PMID:11684705, GO:0015758=Reactome:REACT_212, GO:0005643=GO_REF:0000002, GO:0000087=Reactome:REACT_910, GO:0006810=GO_REF:0000002, GO:0017056=PMID:15229283, GO:0016032=Reactome:REACT_6256, GO:0031965=PMID:15229283, GO:0005975=Reactome:REACT_474, GO:0055085=Reactome:REACT_19118, GO:0010827=Reactome:REACT_6804, GO:0005487=PMID:11684705, GO:0034399=PMID:15229283, GO:0031080=PMID:15146057, GO:0000777=GO_REF:0000039, GO:0000776=PMID:17363900, GO:0015288=GO_REF:0000038, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} Q6PJE1 Nuclear pore complex protein Nup107 protein 20130413 {GO:0005515=IPI, GO:0022415=TAS, GO:0000236=TAS, GO:0019221=TAS, GO:0044281=TAS, GO:0005635=TAS, GO:0051292=IMP, GO:0015031=IEA, GO:0005829=TAS, GO:0008645=TAS, GO:0006406=IDA, GO:0015758=TAS, GO:0005643=IEA, GO:0000087=TAS, GO:0006810=IEA, GO:0017056=IMP, GO:0016032=TAS, GO:0031965=IDA, GO:0005975=TAS, GO:0055085=TAS, GO:0010827=TAS, GO:0005487=IDA, GO:0034399=IDA, GO:0031080=NAS, GO:0000777=IEA, GO:0000776=IDA, GO:0015288=IEA, GO:0000278=TAS, GO:0000090=TAS} M phase of mitotic cell cycle, carbohydrate metabolic process, cytokine-mediated signaling pathway, glucose transport, hexose transport, mRNA export from nucleus, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, nuclear pore complex assembly, protein transport, regulation of glucose transport, small molecule metabolic process, transmembrane transport, transport, viral reproduction, viral reproductive process condensed chromosome kinetochore, cytosol, kinetochore, nuclear envelope, nuclear membrane, nuclear periphery, nuclear pore, nuclear pore outer ring nucleocytoplasmic transporter activity, porin activity, protein binding, structural constituent of nuclear pore Human InterPro:IPR007252 NUP133 IntAct UniProtKB {GO:0005515=PMID:11564755, GO:0000236=Reactome:REACT_682, GO:0022415=Reactome:REACT_6361, GO:0019221=Reactome:REACT_25229, GO:0005635=Reactome:REACT_115827, GO:0044281=Reactome:REACT_111217, GO:0015031=GO_REF:0000037, GO:0005829=Reactome:REACT_150414, GO:0008645=Reactome:REACT_9441, GO:0006406=PMID:11684705, GO:0015758=Reactome:REACT_212, GO:0005643=PMID:17098863, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6256, GO:0006999=PMID:15146057, GO:0048339=GO_REF:0000019, GO:0005975=Reactome:REACT_474, GO:0055085=Reactome:REACT_19118, GO:0010827=Reactome:REACT_6804, GO:0000940=PMID:17363900, GO:0005487=PMID:11684705, GO:0031080=PMID:17363900, GO:0000777=PMID:17098863, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} Q8WUM0 Nuclear pore complex protein Nup133 protein 20130415 {GO:0005515=IPI, GO:0000236=TAS, GO:0022415=TAS, GO:0019221=TAS, GO:0005635=TAS, GO:0044281=TAS, GO:0015031=IEA, GO:0005829=TAS, GO:0008645=TAS, GO:0006406=IDA, GO:0015758=TAS, GO:0005643=IDA, GO:0000087=TAS, GO:0016032=TAS, GO:0006999=IMP, GO:0048339=IEA, GO:0005975=TAS, GO:0055085=TAS, GO:0010827=TAS, GO:0000940=IDA, GO:0005487=IDA, GO:0031080=NAS, GO:0000777=IDA, GO:0000278=TAS, GO:0000090=TAS} M phase of mitotic cell cycle, carbohydrate metabolic process, cytokine-mediated signaling pathway, glucose transport, hexose transport, mRNA export from nucleus, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, nuclear pore organization, paraxial mesoderm development, protein transport, regulation of glucose transport, small molecule metabolic process, transmembrane transport, viral reproduction, viral reproductive process condensed chromosome kinetochore, condensed chromosome outer kinetochore, cytosol, nuclear envelope, nuclear pore, nuclear pore outer ring nucleocytoplasmic transporter activity, protein binding Human UniProtKB:P57740 NUP153 GOC UniProtKB {GO:0005515=PMID:20133940, GO:0022415=Reactome:REACT_6361, GO:0005215=PMID:8110839, GO:0019221=Reactome:REACT_25229, GO:0044281=Reactome:REACT_111217, GO:0046718=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0051292=PMID:12802065, GO:0008645=Reactome:REACT_9441, GO:0005737=GO_REF:0000052, GO:0015758=Reactome:REACT_212, GO:0005643=PMID:15229283, GO:0016032=Reactome:REACT_6256, GO:0017056=PMID:15229283, GO:0031965=GO_REF:0000052, GO:0044615=PMID:11839768, GO:0005975=Reactome:REACT_474, GO:0005730=GO_REF:0000052, GO:0055085=Reactome:REACT_19118, GO:0003677=GO_REF:0000037, GO:0010827=Reactome:REACT_6804, GO:0006913=PMID:22253824, GO:0005487=PMID:22253824, GO:0034399=PMID:15229283, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_115827, GO:0051028=GO_REF:0000037, GO:0075732=GO_REF:0000037, GO:0043495=PMID:15229283, GO:0046832=PMID:22253824, GO:0042405=PMID:11839768} P49790 Nuclear pore complex protein Nup153 protein 20130413 {GO:0005515=IPI, GO:0022415=TAS, GO:0005215=TAS, GO:0019221=TAS, GO:0044281=TAS, GO:0046718=IEA, GO:0015031=IEA, GO:0051292=IMP, GO:0008645=TAS, GO:0005737=IDA, GO:0015758=TAS, GO:0005643=IDA, GO:0016032=TAS, GO:0017056=IMP, GO:0031965=IDA, GO:0044615=IDA, GO:0005975=TAS, GO:0005730=IDA, GO:0055085=TAS, GO:0003677=IEA, GO:0010827=TAS, GO:0006913=IDA, GO:0005487=IDA, GO:0034399=IDA, GO:0008270=IEA, GO:0005654=TAS, GO:0051028=IEA, GO:0075732=IEA, GO:0043495=IMP, GO:0046832=IDA, GO:0042405=IDA} carbohydrate metabolic process, cytokine-mediated signaling pathway, glucose transport, hexose transport, mRNA transport, negative regulation of RNA export from nucleus, nuclear pore complex assembly, nucleocytoplasmic transport, protein transport, regulation of glucose transport, small molecule metabolic process, transmembrane transport, viral entry into host cell, viral penetration into host nucleus, viral reproduction, viral reproductive process cytoplasm, nuclear inclusion body, nuclear membrane, nuclear periphery, nuclear pore, nuclear pore nuclear basket, nucleolus, nucleoplasm DNA binding, nucleocytoplasmic transporter activity, protein anchor, protein binding, structural constituent of nuclear pore, transporter activity, zinc ion binding Human NUP155 Reactome UniProtKB {GO:0022415=Reactome:REACT_6361, GO:0005215=PMID:10191094, GO:0031965=GO_REF:0000039, GO:0005975=Reactome:REACT_474, GO:0019221=Reactome:REACT_25229, GO:0044281=Reactome:REACT_111217, GO:0005635=Reactome:REACT_115827, GO:0006606=GO_REF:0000019, GO:0055085=Reactome:REACT_19118, GO:0010827=Reactome:REACT_6804, GO:0006913=GO_REF:0000002, GO:0008645=Reactome:REACT_9441, GO:0006406=GO_REF:0000019, GO:0015758=Reactome:REACT_212, GO:0005643=GO_REF:0000039, GO:0086014=GO_REF:0000019, GO:0016032=Reactome:REACT_6256, GO:0017056=GO_REF:0000002, GO:0006998=PMID:19070573} O75694 Nuclear pore complex protein Nup155 protein 20130301 {GO:0022415=TAS, GO:0005215=TAS, GO:0031965=IEA, GO:0005975=TAS, GO:0019221=TAS, GO:0044281=TAS, GO:0005635=TAS, GO:0006606=IEA, GO:0055085=TAS, GO:0010827=TAS, GO:0006913=IEA, GO:0008645=TAS, GO:0006406=IEA, GO:0015758=TAS, GO:0005643=IEA, GO:0086014=IEA, GO:0016032=TAS, GO:0017056=IEA, GO:0006998=IDA} carbohydrate metabolic process, cytokine-mediated signaling pathway, glucose transport, hexose transport, mRNA export from nucleus, nuclear envelope organization, nucleocytoplasmic transport, protein import into nucleus, regulation of atrial cardiac muscle cell action potential, regulation of glucose transport, small molecule metabolic process, transmembrane transport, viral reproduction, viral reproductive process nuclear envelope, nuclear membrane, nuclear pore structural constituent of nuclear pore, transporter activity Human NUP160 Reactome UniProtKB {GO:0005515=PMID:15146057, GO:0022415=Reactome:REACT_6361, GO:0000236=Reactome:REACT_682, GO:0005975=Reactome:REACT_474, GO:0019221=Reactome:REACT_25229, GO:0044281=Reactome:REACT_111217, GO:0005635=Reactome:REACT_115827, GO:0015031=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0010827=Reactome:REACT_6804, GO:0008645=Reactome:REACT_9441, GO:0005829=Reactome:REACT_150414, GO:0006406=PMID:11684705, GO:0015758=Reactome:REACT_212, GO:0005487=PMID:11684705, GO:0005643=PMID:17098863, GO:0031080=PMID:17363900, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6256, GO:0000776=PMID:15146057, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} Q12769 Nuclear pore complex protein Nup160 protein 20130301 {GO:0005515=IPI, GO:0022415=TAS, GO:0000236=TAS, GO:0005975=TAS, GO:0019221=TAS, GO:0044281=TAS, GO:0005635=TAS, GO:0015031=IEA, GO:0055085=TAS, GO:0010827=TAS, GO:0008645=TAS, GO:0005829=TAS, GO:0006406=IDA, GO:0015758=TAS, GO:0005487=IDA, GO:0005643=IDA, GO:0031080=NAS, GO:0000087=TAS, GO:0016032=TAS, GO:0000776=IDA, GO:0000278=TAS, GO:0000090=TAS} M phase of mitotic cell cycle, carbohydrate metabolic process, cytokine-mediated signaling pathway, glucose transport, hexose transport, mRNA export from nucleus, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, protein transport, regulation of glucose transport, small molecule metabolic process, transmembrane transport, viral reproduction, viral reproductive process cytosol, kinetochore, nuclear envelope, nuclear pore, nuclear pore outer ring nucleocytoplasmic transporter activity, protein binding Human NUP188 Reactome UniProtKB {GO:0022415=Reactome:REACT_6361, GO:0005975=Reactome:REACT_474, GO:0019221=Reactome:REACT_25229, GO:0005635=Reactome:REACT_115827, GO:0044281=Reactome:REACT_111217, GO:0015031=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0010827=Reactome:REACT_6804, GO:0008645=Reactome:REACT_9441, GO:0015758=Reactome:REACT_212, GO:0005643=GO_REF:0000039, GO:0016032=Reactome:REACT_6256, GO:0051028=GO_REF:0000037} Q5SRE5 Nucleoporin NUP188 homolog protein 20130301 {GO:0022415=TAS, GO:0005975=TAS, GO:0019221=TAS, GO:0005635=TAS, GO:0044281=TAS, GO:0015031=IEA, GO:0055085=TAS, GO:0010827=TAS, GO:0008645=TAS, GO:0015758=TAS, GO:0005643=IEA, GO:0016032=TAS, GO:0051028=IEA} carbohydrate metabolic process, cytokine-mediated signaling pathway, glucose transport, hexose transport, mRNA transport, protein transport, regulation of glucose transport, small molecule metabolic process, transmembrane transport, viral reproduction, viral reproductive process nuclear envelope, nuclear pore Human NUP205 Reactome UniProtKB {GO:0005515=PMID:9348540, GO:0022415=Reactome:REACT_6361, GO:0031965=PMID:15229283, GO:0000059=PMID:9348540, GO:0005975=Reactome:REACT_474, GO:0019221=Reactome:REACT_25229, GO:0044281=Reactome:REACT_111217, GO:0005635=Reactome:REACT_115827, GO:0051292=PMID:15229283, GO:0055085=Reactome:REACT_19118, GO:0010827=Reactome:REACT_6804, GO:0006913=PMID:9348540, GO:0008645=Reactome:REACT_9441, GO:0015758=Reactome:REACT_212, GO:0005643=PMID:15229283, GO:0034399=PMID:15229283, GO:0016032=Reactome:REACT_6256, GO:0017056=PMID:15229283, GO:0051028=GO_REF:0000037} Q92621 Nuclear pore complex protein Nup205 protein 20130301 {GO:0005515=IPI, GO:0022415=TAS, GO:0031965=IDA, GO:0000059=TAS, GO:0005975=TAS, GO:0019221=TAS, GO:0044281=TAS, GO:0005635=TAS, GO:0051292=IMP, GO:0055085=TAS, GO:0010827=TAS, GO:0006913=TAS, GO:0008645=TAS, GO:0015758=TAS, GO:0005643=IDA, GO:0034399=IDA, GO:0016032=TAS, GO:0017056=IMP, GO:0051028=IEA} carbohydrate metabolic process, cytokine-mediated signaling pathway, glucose transport, hexose transport, mRNA transport, nuclear pore complex assembly, nucleocytoplasmic transport, protein import into nucleus, docking, regulation of glucose transport, small molecule metabolic process, transmembrane transport, viral reproduction, viral reproductive process nuclear envelope, nuclear membrane, nuclear periphery, nuclear pore protein binding, structural constituent of nuclear pore Human NUP210 Reactome UniProtKB {GO:0022415=Reactome:REACT_6361, GO:0031965=GO_REF:0000039, GO:0005975=Reactome:REACT_474, GO:0019221=Reactome:REACT_25229, GO:0044281=Reactome:REACT_111217, GO:0005635=Reactome:REACT_115827, GO:0015031=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0010827=Reactome:REACT_6804, GO:0008645=Reactome:REACT_9441, GO:0015758=Reactome:REACT_212, GO:0005643=GO_REF:0000039, GO:0046983=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0016032=Reactome:REACT_6256, GO:0051028=GO_REF:0000037} Q8TEM1 Nuclear pore membrane glycoprotein 210 protein 20130301 {GO:0022415=TAS, GO:0031965=IEA, GO:0005975=TAS, GO:0019221=TAS, GO:0044281=TAS, GO:0005635=TAS, GO:0015031=IEA, GO:0055085=TAS, GO:0010827=TAS, GO:0008645=TAS, GO:0015758=TAS, GO:0005643=IEA, GO:0046983=IEA, GO:0005789=IEA, GO:0016032=TAS, GO:0051028=IEA} carbohydrate metabolic process, cytokine-mediated signaling pathway, glucose transport, hexose transport, mRNA transport, protein transport, regulation of glucose transport, small molecule metabolic process, transmembrane transport, viral reproduction, viral reproductive process endoplasmic reticulum membrane, nuclear envelope, nuclear membrane, nuclear pore protein dimerization activity Human NUP210L UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q5VU65 Nuclear pore membrane glycoprotein 210-like protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 NUP214 Reactome UniProtKB {GO:0005515=PMID:11545741, GO:0022415=Reactome:REACT_6361, GO:0005215=PMID:8108440, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0005975=Reactome:REACT_474, GO:0019221=Reactome:REACT_25229, GO:0044281=Reactome:REACT_111217, GO:0006606=GO_REF:0000019, GO:0055085=Reactome:REACT_19118, GO:0010827=Reactome:REACT_6804, GO:0005829=Reactome:REACT_115827, GO:0008645=Reactome:REACT_9441, GO:0006406=GO_REF:0000019, GO:0015758=Reactome:REACT_212, GO:0005487=GO_REF:0000019, GO:0005643=GO_REF:0000039, GO:0006611=PMID:12191473, GO:0051726=GO_REF:0000019, GO:0016032=Reactome:REACT_6256, GO:0005654=Reactome:REACT_25286} P35658 Nuclear pore complex protein Nup214 protein 20130301 {GO:0005515=IPI, GO:0022415=TAS, GO:0005215=TAS, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0005975=TAS, GO:0019221=TAS, GO:0044281=TAS, GO:0006606=IEA, GO:0055085=TAS, GO:0010827=TAS, GO:0005829=TAS, GO:0008645=TAS, GO:0006406=IEA, GO:0015758=TAS, GO:0005487=IEA, GO:0005643=IEA, GO:0006611=IMP, GO:0051726=IEA, GO:0016032=TAS, GO:0005654=TAS} RNA metabolic process, carbohydrate metabolic process, cytokine-mediated signaling pathway, gene expression, glucose transport, hexose transport, mRNA export from nucleus, mRNA metabolic process, protein export from nucleus, protein import into nucleus, regulation of cell cycle, regulation of glucose transport, small molecule metabolic process, transmembrane transport, viral reproduction, viral reproductive process cytosol, nuclear pore, nucleoplasm nucleocytoplasmic transporter activity, protein binding, transporter activity Human NUP35 HPA UniProtKB {GO:0022415=Reactome:REACT_6361, GO:0031965=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005975=Reactome:REACT_474, GO:0019221=Reactome:REACT_25229, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0005635=Reactome:REACT_115827, GO:0015031=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0010827=Reactome:REACT_6804, GO:0043231=GO_REF:0000052, GO:0008645=Reactome:REACT_9441, GO:0015758=Reactome:REACT_212, GO:0005643=GO_REF:0000039, GO:0016032=Reactome:REACT_6256, GO:0045111=GO_REF:0000052, GO:0051028=GO_REF:0000037} Q8NFH5 Nucleoporin NUP53 protein 20090616 {GO:0022415=TAS, GO:0031965=IDA, GO:0005886=IDA, GO:0005975=TAS, GO:0019221=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0005635=TAS, GO:0015031=IEA, GO:0055085=TAS, GO:0010827=TAS, GO:0043231=IDA, GO:0008645=TAS, GO:0015758=TAS, GO:0005643=IEA, GO:0016032=TAS, GO:0045111=IDA, GO:0051028=IEA} carbohydrate metabolic process, cytokine-mediated signaling pathway, glucose transport, hexose transport, mRNA transport, protein transport, regulation of glucose transport, small molecule metabolic process, transmembrane transport, viral reproduction, viral reproductive process intermediate filament cytoskeleton, intracellular membrane-bounded organelle, nuclear envelope, nuclear membrane, nuclear pore, nucleolus, nucleus, plasma membrane Human NUP37 Reactome UniProtKB {GO:0005515=PMID:15146057, GO:0022415=Reactome:REACT_6361, GO:0000236=Reactome:REACT_682, GO:0005975=Reactome:REACT_474, GO:0019221=Reactome:REACT_25229, GO:0044281=Reactome:REACT_111217, GO:0005635=Reactome:REACT_115827, GO:0015031=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0010827=Reactome:REACT_6804, GO:0008645=Reactome:REACT_9441, GO:0005829=Reactome:REACT_150414, GO:0007059=GO_REF:0000037, GO:0015758=Reactome:REACT_212, GO:0031080=PMID:17363900, GO:0000087=Reactome:REACT_910, GO:0000777=GO_REF:0000039, GO:0016032=Reactome:REACT_6256, GO:0000776=PMID:15146057, GO:0051028=GO_REF:0000037, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q8NFH4 Nucleoporin Nup37 protein 20130301 {GO:0005515=IPI, GO:0022415=TAS, GO:0000236=TAS, GO:0005975=TAS, GO:0019221=TAS, GO:0044281=TAS, GO:0005635=TAS, GO:0015031=IEA, GO:0055085=TAS, GO:0010827=TAS, GO:0008645=TAS, GO:0005829=TAS, GO:0007059=IEA, GO:0015758=TAS, GO:0031080=NAS, GO:0000087=TAS, GO:0000777=IEA, GO:0016032=TAS, GO:0000776=IDA, GO:0051028=IEA, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, carbohydrate metabolic process, cell division, chromosome segregation, cytokine-mediated signaling pathway, glucose transport, hexose transport, mRNA transport, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, protein transport, regulation of glucose transport, small molecule metabolic process, transmembrane transport, viral reproduction, viral reproductive process condensed chromosome kinetochore, cytosol, kinetochore, nuclear envelope, nuclear pore outer ring protein binding Human NUP43 Reactome UniProtKB {GO:0005515=PMID:15146057, GO:0022415=Reactome:REACT_6361, GO:0000236=Reactome:REACT_682, GO:0005975=Reactome:REACT_474, GO:0019221=Reactome:REACT_25229, GO:0044281=Reactome:REACT_111217, GO:0005635=Reactome:REACT_115827, GO:0015031=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0010827=Reactome:REACT_6804, GO:0008645=Reactome:REACT_9441, GO:0005829=Reactome:REACT_150414, GO:0007059=GO_REF:0000037, GO:0015758=Reactome:REACT_212, GO:0031080=PMID:17363900, GO:0000087=Reactome:REACT_910, GO:0000777=GO_REF:0000039, GO:0016032=Reactome:REACT_6256, GO:0000776=PMID:15146057, GO:0051028=GO_REF:0000037, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q8NFH3 Nucleoporin Nup43 protein 20130301 {GO:0005515=IPI, GO:0022415=TAS, GO:0000236=TAS, GO:0005975=TAS, GO:0019221=TAS, GO:0044281=TAS, GO:0005635=TAS, GO:0015031=IEA, GO:0055085=TAS, GO:0010827=TAS, GO:0008645=TAS, GO:0005829=TAS, GO:0007059=IEA, GO:0015758=TAS, GO:0031080=NAS, GO:0000087=TAS, GO:0000777=IEA, GO:0016032=TAS, GO:0000776=IDA, GO:0051028=IEA, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, carbohydrate metabolic process, cell division, chromosome segregation, cytokine-mediated signaling pathway, glucose transport, hexose transport, mRNA transport, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, protein transport, regulation of glucose transport, small molecule metabolic process, transmembrane transport, viral reproduction, viral reproductive process condensed chromosome kinetochore, cytosol, kinetochore, nuclear envelope, nuclear pore outer ring protein binding Human NUP50 Reactome UniProtKB {GO:0005515=PMID:16648475, GO:0022415=Reactome:REACT_6361, GO:0031965=PMID:12802065, GO:0005975=Reactome:REACT_474, GO:0019221=Reactome:REACT_25229, GO:0046907=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0015031=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0010827=Reactome:REACT_6804, GO:0008645=Reactome:REACT_9441, GO:0015758=Reactome:REACT_212, GO:0005643=GO_REF:0000039, GO:0016032=Reactome:REACT_6256, GO:0005654=Reactome:REACT_115827, GO:0051028=GO_REF:0000037} Q9UKX7 Nuclear pore complex protein Nup50 protein 20130301 {GO:0005515=IPI, GO:0022415=TAS, GO:0031965=IDA, GO:0005975=TAS, GO:0019221=TAS, GO:0046907=IEA, GO:0044281=TAS, GO:0015031=IEA, GO:0055085=TAS, GO:0010827=TAS, GO:0008645=TAS, GO:0015758=TAS, GO:0005643=IEA, GO:0016032=TAS, GO:0005654=TAS, GO:0051028=IEA} carbohydrate metabolic process, cytokine-mediated signaling pathway, glucose transport, hexose transport, intracellular transport, mRNA transport, protein transport, regulation of glucose transport, small molecule metabolic process, transmembrane transport, viral reproduction, viral reproductive process nuclear membrane, nuclear pore, nucleoplasm protein binding Human NUP54 Reactome UniProtKB {GO:0022415=Reactome:REACT_6361, GO:0031965=GO_REF:0000039, GO:0005975=Reactome:REACT_474, GO:0019221=Reactome:REACT_25229, GO:0044281=Reactome:REACT_111217, GO:0006605=GO_REF:0000019, GO:0005635=Reactome:REACT_115827, GO:0055085=Reactome:REACT_19118, GO:0010827=Reactome:REACT_6804, GO:0008645=Reactome:REACT_9441, GO:0005737=PMID:8707840, GO:0005487=GO_REF:0000019, GO:0015758=Reactome:REACT_212, GO:0005643=GO_REF:0000039, GO:0016032=Reactome:REACT_6256, GO:0005654=PMID:8707840, GO:0051028=GO_REF:0000037} Q7Z3B4 Nucleoporin p54 protein 20130301 {GO:0022415=TAS, GO:0031965=IEA, GO:0005975=TAS, GO:0019221=TAS, GO:0044281=TAS, GO:0006605=IEA, GO:0005635=TAS, GO:0055085=TAS, GO:0010827=TAS, GO:0008645=TAS, GO:0005737=TAS, GO:0005487=IEA, GO:0015758=TAS, GO:0005643=IEA, GO:0016032=TAS, GO:0005654=TAS, GO:0051028=IEA} carbohydrate metabolic process, cytokine-mediated signaling pathway, glucose transport, hexose transport, mRNA transport, protein targeting, regulation of glucose transport, small molecule metabolic process, transmembrane transport, viral reproduction, viral reproductive process cytoplasm, nuclear envelope, nuclear membrane, nuclear pore, nucleoplasm nucleocytoplasmic transporter activity Human NUP62 GOC UniProtKB {GO:0005515=PMID:21078624, GO:0022415=Reactome:REACT_6361, GO:0008219=PMID:11244088, GO:0043130=PMID:8702753, GO:0008285=PMID:11013214, GO:0019221=Reactome:REACT_25229, GO:0030159=PMID:11244088, GO:0044281=Reactome:REACT_111217, GO:0005635=GO_REF:0000054, GO:0046578=PMID:11553620, GO:0015031=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0008645=Reactome:REACT_9441, GO:0046966=PMID:15625236, GO:0031074=PMID:8589458, GO:0043069=PMID:11244088, GO:0005737=PMID:10373430, GO:0015758=Reactome:REACT_212, GO:0005643=PMID:1915414, GO:0016032=Reactome:REACT_6256, GO:0017056=GO_REF:0000002, GO:0043123=PMID:10356400, GO:0042169=PMID:8650207, GO:0031965=GO_REF:0000052, GO:0043066=PMID:11755531, GO:0005975=Reactome:REACT_474, GO:0045742=PMID:11244088, GO:0009966=PMID:8702753, GO:0055085=Reactome:REACT_19118, GO:0010827=Reactome:REACT_6804, GO:0006351=PMID:10373430, GO:0006913=PMID:8589458, GO:0046930=PMID:15175862, GO:0000922=GO_REF:0000039, GO:0009755=PMID:15625236, GO:0005487=PMID:8589458, GO:0030529=PMID:18809582, GO:0003682=PMID:11852044, GO:0051028=GO_REF:0000037, GO:0045893=PMID:15625236, GO:0007166=PMID:10373430} P37198 Nuclear pore glycoprotein p62 protein 20130413 {GO:0005515=IPI, GO:0022415=TAS, GO:0008219=IMP, GO:0043130=IDA, GO:0008285=IDA, GO:0019221=TAS, GO:0030159=IDA, GO:0044281=TAS, GO:0005635=IDA, GO:0046578=NAS, GO:0015031=IEA, GO:0043231=IDA, GO:0008645=TAS, GO:0046966=IPI, GO:0031074=NAS, GO:0043069=IDA, GO:0005737=NAS, GO:0015758=TAS, GO:0005643=IDA, GO:0016032=TAS, GO:0017056=IEA, GO:0043123=IDA, GO:0042169=IDA, GO:0031965=IDA, GO:0043066=IDA, GO:0005975=TAS, GO:0045742=NAS, GO:0009966=NAS, GO:0055085=TAS, GO:0010827=TAS, GO:0006351=IDA, GO:0006913=NAS, GO:0046930=NAS, GO:0000922=IEA, GO:0009755=NAS, GO:0005487=NAS, GO:0030529=IDA, GO:0003682=NAS, GO:0051028=IEA, GO:0045893=IDA, GO:0007166=NAS} carbohydrate metabolic process, cell death, cell surface receptor signaling pathway, cytokine-mediated signaling pathway, glucose transport, hexose transport, hormone-mediated signaling pathway, mRNA transport, negative regulation of apoptotic process, negative regulation of cell proliferation, negative regulation of programmed cell death, nucleocytoplasmic transport, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of epidermal growth factor receptor signaling pathway, positive regulation of transcription, DNA-dependent, protein transport, regulation of Ras protein signal transduction, regulation of glucose transport, regulation of signal transduction, small molecule metabolic process, transcription, DNA-dependent, transmembrane transport, viral reproduction, viral reproductive process cytoplasm, intracellular membrane-bounded organelle, nuclear envelope, nuclear membrane, nuclear pore, nucleocytoplasmic shuttling complex, pore complex, ribonucleoprotein complex, spindle pole SH2 domain binding, chromatin binding, nucleocytoplasmic transporter activity, protein binding, receptor signaling complex scaffold activity, structural constituent of nuclear pore, thyroid hormone receptor binding, ubiquitin binding Human NUP62CL UniProtKB UniProtKB {GO:0005643=GO_REF:0000002, GO:0017056=GO_REF:0000002, GO:0015031=GO_REF:0000037} Q9H1M0 Nucleoporin-62 C-terminal-like protein protein 20130413 {GO:0005643=IEA, GO:0017056=IEA, GO:0015031=IEA} protein transport nuclear pore structural constituent of nuclear pore Human UniProtKB-KW:KW-0653 NUP85 Reactome UniProtKB {GO:0005515=PMID:15146057, GO:0000236=Reactome:REACT_682, GO:0022415=Reactome:REACT_6361, GO:0030032=GO_REF:0000019, GO:0019221=Reactome:REACT_25229, GO:0005635=Reactome:REACT_115827, GO:0044281=Reactome:REACT_111217, GO:0015031=GO_REF:0000037, GO:0005829=Reactome:REACT_150414, GO:0008645=Reactome:REACT_9441, GO:0015758=Reactome:REACT_212, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6256, GO:0031965=GO_REF:0000039, GO:0005975=Reactome:REACT_474, GO:0005819=GO_REF:0000039, GO:0055085=Reactome:REACT_19118, GO:0010827=Reactome:REACT_6804, GO:0031080=PMID:17363900, GO:0000777=GO_REF:0000039, GO:0000776=PMID:15146057, GO:0051028=GO_REF:0000037, GO:0048246=GO_REF:0000019, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} Q9BW27 Nuclear pore complex protein Nup85 protein 20130301 {GO:0005515=IPI, GO:0000236=TAS, GO:0022415=TAS, GO:0030032=IEA, GO:0019221=TAS, GO:0005635=TAS, GO:0044281=TAS, GO:0015031=IEA, GO:0005829=TAS, GO:0008645=TAS, GO:0015758=TAS, GO:0000087=TAS, GO:0016032=TAS, GO:0031965=IEA, GO:0005975=TAS, GO:0005819=IEA, GO:0055085=TAS, GO:0010827=TAS, GO:0031080=NAS, GO:0000777=IEA, GO:0000776=IDA, GO:0051028=IEA, GO:0048246=IEA, GO:0000278=TAS, GO:0000090=TAS} M phase of mitotic cell cycle, carbohydrate metabolic process, cytokine-mediated signaling pathway, glucose transport, hexose transport, lamellipodium assembly, mRNA transport, macrophage chemotaxis, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, protein transport, regulation of glucose transport, small molecule metabolic process, transmembrane transport, viral reproduction, viral reproductive process condensed chromosome kinetochore, cytosol, kinetochore, nuclear envelope, nuclear membrane, nuclear pore outer ring, spindle protein binding Human NUP88 HPA UniProtKB {GO:0005215=PMID:9049309, GO:0022415=Reactome:REACT_6361, GO:0005975=Reactome:REACT_474, GO:0019221=Reactome:REACT_25229, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0015031=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0010827=Reactome:REACT_6804, GO:0005829=Reactome:REACT_115827, GO:0008645=Reactome:REACT_9441, GO:0015758=Reactome:REACT_212, GO:0005643=GO_REF:0000039, GO:0016032=Reactome:REACT_6256, GO:0051028=GO_REF:0000037} Q99567 Nuclear pore complex protein Nup88 protein 20101115 {GO:0005215=TAS, GO:0022415=TAS, GO:0005975=TAS, GO:0019221=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0015031=IEA, GO:0055085=TAS, GO:0010827=TAS, GO:0005829=TAS, GO:0008645=TAS, GO:0015758=TAS, GO:0005643=IEA, GO:0016032=TAS, GO:0051028=IEA} carbohydrate metabolic process, cytokine-mediated signaling pathway, glucose transport, hexose transport, mRNA transport, protein transport, regulation of glucose transport, small molecule metabolic process, transmembrane transport, viral reproduction, viral reproductive process cytosol, nuclear pore, nucleolus, nucleus transporter activity NOT Human NUP93 Reactome UniProtKB {GO:0022415=Reactome:REACT_6361, GO:0031965=PMID:15229283, GO:0005975=Reactome:REACT_474, GO:0019221=Reactome:REACT_25229, GO:0044281=Reactome:REACT_111217, GO:0005635=Reactome:REACT_115827, GO:0015031=GO_REF:0000037, GO:0051292=PMID:15229283, GO:0055085=Reactome:REACT_19118, GO:0010827=Reactome:REACT_6804, GO:0008645=Reactome:REACT_9441, GO:0015758=Reactome:REACT_212, GO:0005643=PMID:15229283, GO:0034399=PMID:15229283, GO:0006810=GO_REF:0000002, GO:0016032=Reactome:REACT_6256, GO:0017056=PMID:15229283, GO:0051028=GO_REF:0000037} Q8N1F7 Nuclear pore complex protein Nup93 protein 20130301 {GO:0022415=TAS, GO:0031965=IDA, GO:0005975=TAS, GO:0019221=TAS, GO:0044281=TAS, GO:0005635=TAS, GO:0015031=IEA, GO:0051292=IMP, GO:0055085=TAS, GO:0010827=TAS, GO:0008645=TAS, GO:0015758=TAS, GO:0005643=IDA, GO:0034399=IDA, GO:0006810=IEA, GO:0016032=TAS, GO:0017056=IMP, GO:0051028=IEA} carbohydrate metabolic process, cytokine-mediated signaling pathway, glucose transport, hexose transport, mRNA transport, nuclear pore complex assembly, protein transport, regulation of glucose transport, small molecule metabolic process, transmembrane transport, transport, viral reproduction, viral reproductive process nuclear envelope, nuclear membrane, nuclear periphery, nuclear pore structural constituent of nuclear pore Human NUP98 Reactome UniProtKB {GO:0005515=PMID:15146057, GO:0022415=Reactome:REACT_6361, GO:0005215=PMID:7736573, GO:0000236=Reactome:REACT_682, GO:0000059=PMID:15229283, GO:0019221=Reactome:REACT_25229, GO:0044281=Reactome:REACT_111217, GO:0005635=Reactome:REACT_115827, GO:0051292=PMID:15229283, GO:0008645=Reactome:REACT_9441, GO:0005829=Reactome:REACT_150414, GO:0015758=Reactome:REACT_212, GO:0005643=PMID:15229283, GO:0000087=Reactome:REACT_910, GO:0006810=GO_REF:0000002, GO:0016032=Reactome:REACT_6256, GO:0017056=PMID:15229283, GO:0006999=PMID:9348540, GO:0042277=GO_REF:0000019, GO:0031965=PMID:15229283, GO:0044615=PMID:11839768, GO:0005975=Reactome:REACT_474, GO:0055085=Reactome:REACT_19118, GO:0010827=Reactome:REACT_6804, GO:0006913=PMID:9348540, GO:0006260=PMID:9348540, GO:0034399=PMID:15229283, GO:0019048=GO_REF:0000037, GO:0031080=PMID:15146057, GO:0000776=PMID:15146057, GO:0005654=GO_REF:0000019, GO:0051028=GO_REF:0000037, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0042405=PMID:11839768} P52948 Nuclear pore complex protein Nup98-Nup96 protein 20130301 {GO:0005515=IPI, GO:0022415=TAS, GO:0005215=TAS, GO:0000236=TAS, GO:0000059=NAS, GO:0019221=TAS, GO:0044281=TAS, GO:0005635=TAS, GO:0051292=IMP, GO:0008645=TAS, GO:0005829=TAS, GO:0015758=TAS, GO:0005643=IDA, GO:0000087=TAS, GO:0006810=IEA, GO:0016032=TAS, GO:0017056=IMP, GO:0006999=NAS, GO:0042277=IEA, GO:0031965=IDA, GO:0044615=IDA, GO:0005975=TAS, GO:0055085=TAS, GO:0010827=TAS, GO:0006913=TAS, GO:0006260=IMP, GO:0034399=IDA, GO:0019048=IEA, GO:0031080=NAS, GO:0000776=IDA, GO:0005654=IEA, GO:0051028=IEA, GO:0000278=TAS, GO:0000090=TAS, GO:0042405=IDA} DNA replication, M phase of mitotic cell cycle, carbohydrate metabolic process, cytokine-mediated signaling pathway, glucose transport, hexose transport, mRNA transport, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, nuclear pore complex assembly, nuclear pore organization, nucleocytoplasmic transport, protein import into nucleus, docking, regulation of glucose transport, small molecule metabolic process, transmembrane transport, transport, viral reproduction, viral reproductive process, virus-host interaction cytosol, kinetochore, nuclear envelope, nuclear inclusion body, nuclear membrane, nuclear periphery, nuclear pore, nuclear pore nuclear basket, nuclear pore outer ring, nucleoplasm peptide binding, protein binding, structural constituent of nuclear pore, transporter activity Human NUPL1 Reactome UniProtKB {GO:0022415=Reactome:REACT_6361, GO:0031965=GO_REF:0000039, GO:0005975=Reactome:REACT_474, GO:0019221=Reactome:REACT_25229, GO:0044281=Reactome:REACT_111217, GO:0005635=Reactome:REACT_115827, GO:0015031=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0010827=Reactome:REACT_6804, GO:0006913=GO_REF:0000002, GO:0008645=Reactome:REACT_9441, GO:0005487=GO_REF:0000019, GO:0015758=Reactome:REACT_212, GO:0005643=GO_REF:0000039, GO:0016032=Reactome:REACT_6256, GO:0051028=GO_REF:0000037} Q9BVL2 Nucleoporin p58/p45 protein 20130301 {GO:0022415=TAS, GO:0031965=IEA, GO:0005975=TAS, GO:0019221=TAS, GO:0044281=TAS, GO:0005635=TAS, GO:0015031=IEA, GO:0055085=TAS, GO:0010827=TAS, GO:0006913=IEA, GO:0008645=TAS, GO:0005487=IEA, GO:0015758=TAS, GO:0005643=IEA, GO:0016032=TAS, GO:0051028=IEA} carbohydrate metabolic process, cytokine-mediated signaling pathway, glucose transport, hexose transport, mRNA transport, nucleocytoplasmic transport, protein transport, regulation of glucose transport, small molecule metabolic process, transmembrane transport, viral reproduction, viral reproductive process nuclear envelope, nuclear membrane, nuclear pore nucleocytoplasmic transporter activity Human NUPL2 Reactome UniProtKB {GO:0022415=Reactome:REACT_6361, GO:0031965=GO_REF:0000039, GO:0005975=Reactome:REACT_474, GO:0019221=Reactome:REACT_25229, GO:0005634=PMID:10358091, GO:0044281=Reactome:REACT_111217, GO:0003676=GO_REF:0000002, GO:0055085=Reactome:REACT_19118, GO:0010827=Reactome:REACT_6804, GO:0005829=Reactome:REACT_115827, GO:0008645=Reactome:REACT_9441, GO:0015758=Reactome:REACT_212, GO:0005643=GO_REF:0000039, GO:0006611=PMID:10358091, GO:0005049=PMID:10358091, GO:0016032=Reactome:REACT_6256, GO:0008270=GO_REF:0000002, GO:0051028=GO_REF:0000037} O15504 Nucleoporin-like protein 2 protein 20130301 {GO:0022415=TAS, GO:0031965=IEA, GO:0005975=TAS, GO:0019221=TAS, GO:0005634=TAS, GO:0044281=TAS, GO:0003676=IEA, GO:0055085=TAS, GO:0010827=TAS, GO:0005829=TAS, GO:0008645=TAS, GO:0015758=TAS, GO:0005643=IEA, GO:0006611=TAS, GO:0005049=TAS, GO:0016032=TAS, GO:0008270=IEA, GO:0051028=IEA} carbohydrate metabolic process, cytokine-mediated signaling pathway, glucose transport, hexose transport, mRNA transport, protein export from nucleus, regulation of glucose transport, small molecule metabolic process, transmembrane transport, viral reproduction, viral reproductive process cytosol, nuclear membrane, nuclear pore, nucleus nuclear export signal receptor activity, nucleic acid binding, zinc ion binding Human NUPR1 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0002526=GO_REF:0000019, GO:0048147=GO_REF:0000019, GO:0009636=GO_REF:0000019, GO:0005634=PMID:10092851, GO:0006917=GO_REF:0000029, GO:0035914=GO_REF:0000019, GO:0045786=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0031401=GO_REF:0000019, GO:0003674=GO_REF:0000015, GO:0042771=GO_REF:0000019, GO:0006461=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0016049=PMID:10092851, GO:2000194=GO_REF:0000019, GO:0006473=GO_REF:0000019, GO:0008584=GO_REF:0000019} O60356 Nuclear protein 1 protein 20061026 {GO:0006355=IEA, GO:0002526=IEA, GO:0048147=IEA, GO:0009636=IEA, GO:0005634=IDA, GO:0006917=NAS, GO:0035914=IEA, GO:0045786=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0031401=IEA, GO:0003674=ND, GO:0042771=IEA, GO:0006461=IEA, GO:0003682=IEA, GO:0016049=IDA, GO:2000194=IEA, GO:0006473=IEA, GO:0008584=IEA} acute inflammatory response, cell growth, induction of apoptosis, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, male gonad development, negative regulation of cell cycle, negative regulation of fibroblast proliferation, positive regulation of protein modification process, protein acetylation, protein complex assembly, regulation of female gonad development, regulation of transcription, DNA-dependent, response to toxic substance, skeletal muscle cell differentiation, transcription, DNA-dependent nucleus DNA binding, chromatin binding, molecular_function Human NUSAP1 HPA UniProtKB {GO:0008017=GO_REF:0000019, GO:0007076=PMID:12963707, GO:0000281=PMID:12963707, GO:0005694=GO_REF:0000039, GO:0005874=GO_REF:0000002, GO:0005819=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0045840=PMID:12963707, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0000070=PMID:12963707, GO:0040001=PMID:12963707, GO:0005876=GO_REF:0000019} Q9BXS6 Nucleolar and spindle-associated protein 1 protein 20120912 {GO:0008017=IEA, GO:0007076=IDA, GO:0000281=IDA, GO:0005694=IEA, GO:0005874=IEA, GO:0005819=IEA, GO:0005730=IDA, GO:0045840=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0005737=IDA, GO:0000070=IDA, GO:0040001=IDA, GO:0005876=IEA} cytokinesis after mitosis, establishment of mitotic spindle localization, mitotic chromosome condensation, mitotic sister chromatid segregation, positive regulation of mitosis chromosome, cytoplasm, microtubule, nucleolus, nucleus, spindle, spindle microtubule DNA binding, microtubule binding Human NUTF2 HPA UniProtKB {GO:0005515=PMID:7744965, GO:0005622=GO_REF:0000002, GO:0005215=PMID:7744965, GO:0005643=PMID:7744965, GO:0015630=GO_REF:0000052, GO:0006611=PMID:16449645, GO:0006810=GO_REF:0000002, GO:0005829=PMID:7744965} P61970 Nuclear transport factor 2 protein 20111111 {GO:0005515=IPI, GO:0005622=IEA, GO:0005215=TAS, GO:0005643=TAS, GO:0015630=IDA, GO:0006611=IDA, GO:0006810=IEA, GO:0005829=TAS} protein export from nucleus, transport cytosol, intracellular, microtubule cytoskeleton, nuclear pore protein binding, transporter activity Human NVL HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0017111=GO_REF:0000002, GO:0016235=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037} O15381 Nuclear valosin-containing protein-like protein 20101115 {GO:0005737=IDA, GO:0017111=IEA, GO:0016235=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0005524=IEA} aggresome, cytoplasm, nucleolus, nucleus ATP binding, nucleoside-triphosphatase activity Human NXF1 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0010467=Reactome:REACT_71, GO:0003723=GO_REF:0000002, GO:0005634=GO_REF:0000002, GO:0003729=GO_REF:0000019, GO:0005829=Reactome:REACT_2104, GO:0005737=GO_REF:0000002, GO:0006406=Reactome:REACT_1597, GO:0000166=GO_REF:0000002, GO:0005487=GO_REF:0000019, GO:0016607=GO_REF:0000039, GO:0005643=GO_REF:0000019, GO:0016973=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0005654=Reactome:REACT_2104, GO:0051028=GO_REF:0000002, GO:0042405=GO_REF:0000019} Q9UBU9 Nuclear RNA export factor 1 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0003723=IEA, GO:0005634=IEA, GO:0003729=IEA, GO:0005829=TAS, GO:0005737=IEA, GO:0006406=TAS, GO:0000166=IEA, GO:0005487=IEA, GO:0016607=IEA, GO:0005643=IEA, GO:0016973=IEA, GO:0019048=IEA, GO:0005654=TAS, GO:0051028=IEA, GO:0042405=IEA} gene expression, mRNA export from nucleus, mRNA transport, poly(A)+ mRNA export from nucleus, virus-host interaction cytoplasm, cytosol, nuclear inclusion body, nuclear pore, nuclear speck, nucleoplasm, nucleus RNA binding, mRNA binding, nucleocytoplasmic transporter activity, nucleotide binding, protein binding Human UniProtKB:Q07955 NXF2 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0006406=PMID:11073998, GO:0000166=GO_REF:0000002, GO:0003723=PMID:11073998, GO:0005730=GO_REF:0000052, GO:0042272=PMID:11073998, GO:0007275=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0050658=GO_REF:0000024, GO:0015629=GO_REF:0000052} Q9GZY0 Nuclear RNA export factor 2 protein 20080205 {GO:0005737=IDA, GO:0006406=NAS, GO:0000166=IEA, GO:0003723=NAS, GO:0005730=IDA, GO:0042272=NAS, GO:0007275=ISS, GO:0005634=IDA, GO:0050658=ISS, GO:0015629=IDA} RNA transport, mRNA export from nucleus, multicellular organismal development actin cytoskeleton, cytoplasm, nuclear RNA export factor complex, nucleolus, nucleus RNA binding, nucleotide binding Human NXF3 HPA UniProtKB {GO:0005515=PMID:19060904, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0006406=PMID:11545741, GO:0000166=GO_REF:0000002, GO:0016973=GO_REF:0000019, GO:0003723=GO_REF:0000002, GO:0006810=GO_REF:0000002, GO:0042272=PMID:11545741, GO:0005634=PMID:11545741, GO:0003729=GO_REF:0000019} Q9H4D5 Nuclear RNA export factor 3 protein 20080818 {GO:0005515=IPI, GO:0005622=IEA, GO:0005737=IDA, GO:0006406=IDA, GO:0000166=IEA, GO:0016973=IEA, GO:0003723=IEA, GO:0006810=IEA, GO:0042272=IDA, GO:0005634=IDA, GO:0003729=IEA} mRNA export from nucleus, poly(A)+ mRNA export from nucleus, transport cytoplasm, intracellular, nuclear RNA export factor complex, nucleus RNA binding, mRNA binding, nucleotide binding, protein binding Human NXF5 HPA UniProtKB {GO:0005515=PMID:11566096, GO:0005737=GO_REF:0000052, GO:0006406=PMID:11566096, GO:0000166=GO_REF:0000002, GO:0003723=PMID:11566096, GO:0005730=GO_REF:0000052, GO:0050658=PMID:11566096, GO:0007275=PMID:11566096, GO:0005634=GO_REF:0000052, GO:0015629=GO_REF:0000052} Q9H1B4 Nuclear RNA export factor 5 protein 20080205 {GO:0005515=IPI, GO:0005737=IDA, GO:0006406=IDA, GO:0000166=IEA, GO:0003723=IDA, GO:0005730=IDA, GO:0050658=IDA, GO:0007275=IEP, GO:0005634=IDA, GO:0015629=IDA} RNA transport, mRNA export from nucleus, multicellular organismal development actin cytoskeleton, cytoplasm, nucleolus, nucleus RNA binding, nucleotide binding, protein binding Human NXN UniProtKB UniProtKB {GO:0030178=GO_REF:0000024, GO:0004791=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0031397=GO_REF:0000024, GO:0072358=GO_REF:0000024, GO:0016055=GO_REF:0000037, GO:0047134=GO_REF:0000003, GO:0030154=GO_REF:0000037, GO:0005829=GO_REF:0000039} Q6DKJ4 Nucleoredoxin protein 20120329 {GO:0030178=ISS, GO:0004791=IEA, GO:0005634=IEA, GO:0031397=ISS, GO:0072358=ISS, GO:0016055=IEA, GO:0047134=IEA, GO:0030154=IEA, GO:0005829=IEA} Wnt receptor signaling pathway, cardiovascular system development, cell differentiation, negative regulation of Wnt receptor signaling pathway, negative regulation of protein ubiquitination cytosol, nucleus protein-disulfide reductase activity, thioredoxin-disulfide reductase activity Human UniProtKB:P97346 NXNL1 UniProtKB UniProtKB {GO:0005640=GO_REF:0000039, GO:0005739=GO_REF:0000019} Q96CM4 Nucleoredoxin-like protein 1 protein 20130413 {GO:0005640=IEA, GO:0005739=IEA} mitochondrion, nuclear outer membrane Human UniProtKB-SubCell:SL-0183 NXPH1 UniProtKB UniProtKB {GO:0005102=GO_REF:0000019, GO:0005576=GO_REF:0000039} P58417 Neurexophilin-1 protein 20130413 {GO:0005102=IEA, GO:0005576=IEA} extracellular region receptor binding Human UniProtKB-SubCell:SL-0243 NXPH2 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0007218=PMID:9570794, GO:0005576=GO_REF:0000029} O95156 Neurexophilin-2 protein 20111129 {GO:0003674=ND, GO:0007218=NAS, GO:0005576=NAS} neuropeptide signaling pathway extracellular region molecular_function Human NXPH3 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0007218=PMID:9570794, GO:0005102=GO_REF:0000019, GO:0005576=GO_REF:0000029} O95157 Neurexophilin-3 protein 20061026 {GO:0003674=ND, GO:0007218=NAS, GO:0005102=IEA, GO:0005576=NAS} neuropeptide signaling pathway extracellular region molecular_function, receptor binding Human NXT1 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0006405=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0005643=GO_REF:0000019, GO:0008536=GO_REF:0000019, GO:0006611=GO_REF:0000019} Q9UKK6 NTF2-related export protein 1 protein 20130415 {GO:0005515=IPI, GO:0006405=IEA, GO:0005737=IEA, GO:0005643=IEA, GO:0008536=IEA, GO:0006611=IEA} RNA export from nucleus, protein export from nucleus cytoplasm, nuclear pore Ran GTPase binding, protein binding Human UniProtKB:Q9H4D5 NXT2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0051028=GO_REF:0000037, GO:0015031=GO_REF:0000037} Q9NPJ8 NTF2-related export protein 2 protein 20130413 {GO:0005737=IEA, GO:0005634=IEA, GO:0051028=IEA, GO:0015031=IEA} mRNA transport, protein transport cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 NYAP1 UniProtKB UniProtKB {GO:0048812=GO_REF:0000024, GO:0014065=GO_REF:0000024} Q6ZVC0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1 protein 20120430 {GO:0048812=ISS, GO:0014065=ISS} neuron projection morphogenesis, phosphatidylinositol 3-kinase cascade Human UniProtKB:Q6PFX7 NYNRIN BHF-UCL UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0015074=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037, GO:0003676=GO_REF:0000002} Q9P2P1 Protein NYNRIN protein 20130118 {GO:0003674=ND, GO:0008150=ND, GO:0015074=IEA, GO:0005575=ND, GO:0016021=IEA, GO:0003676=IEA} DNA integration, biological_process cellular_component, integral to membrane molecular_function, nucleic acid binding Human OAS1 Reactome UniProtKB {GO:0003725=PMID:12799444, GO:0005783=GO_REF:0000039, GO:0001730=PMID:12799444, GO:0019221=Reactome:REACT_25229, GO:0016779=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0009615=PMID:18931074, GO:0005524=PMID:21142819, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_25192, GO:0005739=GO_REF:0000039, GO:0006955=GO_REF:0000002, GO:0051607=GO_REF:0000037, GO:0060337=Reactome:REACT_25162, GO:0016740=GO_REF:0000002, GO:0060333=Reactome:REACT_25078, GO:0045071=PMID:18931074} P00973 2'-5'-oligoadenylate synthase 1 protein 20130228 {GO:0003725=IDA, GO:0005783=IEA, GO:0001730=IDA, GO:0019221=TAS, GO:0016779=IEA, GO:0005576=IEA, GO:0005634=IEA, GO:0009615=IDA, GO:0005524=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0006955=IEA, GO:0051607=IEA, GO:0060337=TAS, GO:0016740=IEA, GO:0060333=TAS, GO:0045071=IDA} cytokine-mediated signaling pathway, defense response to virus, immune response, interferon-gamma-mediated signaling pathway, negative regulation of viral genome replication, response to virus, type I interferon-mediated signaling pathway cytosol, endoplasmic reticulum, extracellular region, mitochondrion, nucleus 2'-5'-oligoadenylate synthetase activity, ATP binding, double-stranded RNA binding, metal ion binding, nucleotidyltransferase activity, transferase activity Human OAS2 Reactome UniProtKB {GO:0003725=PMID:10464285, GO:0048471=PMID:19923450, GO:0005783=GO_REF:0000039, GO:0018377=PMID:9880569, GO:0001730=PMID:10464285, GO:0019221=Reactome:REACT_25229, GO:0005634=GO_REF:0000039, GO:0009615=PMID:21142819, GO:0005524=PMID:10464285, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_25192, GO:0043231=PMID:2440675, GO:0006401=GO_REF:0000019, GO:0005739=GO_REF:0000039, GO:0051607=GO_REF:0000037, GO:0006139=PMID:2440675, GO:0006955=GO_REF:0000002, GO:0060337=Reactome:REACT_25162, GO:0016020=PMID:2440675, GO:0006486=PMID:9880569, GO:0016740=GO_REF:0000002, GO:0060333=Reactome:REACT_25078} P29728 2'-5'-oligoadenylate synthase 2 protein 20130228 {GO:0003725=IMP, GO:0048471=IDA, GO:0005783=IEA, GO:0018377=IMP, GO:0001730=IMP, GO:0019221=TAS, GO:0005634=IEA, GO:0009615=TAS, GO:0005524=IMP, GO:0046872=IEA, GO:0005829=TAS, GO:0043231=TAS, GO:0006401=IEA, GO:0005739=IEA, GO:0051607=IEA, GO:0006139=TAS, GO:0006955=IEA, GO:0060337=TAS, GO:0016020=TAS, GO:0006486=IDA, GO:0016740=IEA, GO:0060333=TAS} RNA catabolic process, cytokine-mediated signaling pathway, defense response to virus, immune response, interferon-gamma-mediated signaling pathway, nucleobase-containing compound metabolic process, protein glycosylation, protein myristoylation, response to virus, type I interferon-mediated signaling pathway cytosol, endoplasmic reticulum, intracellular membrane-bounded organelle, membrane, mitochondrion, nucleus, perinuclear region of cytoplasm 2'-5'-oligoadenylate synthetase activity, ATP binding, double-stranded RNA binding, metal ion binding, transferase activity Human OAS3 IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0003725=PMID:9880533, GO:0001730=PMID:9880533, GO:0019221=Reactome:REACT_25229, GO:0005634=GO_REF:0000039, GO:0009615=PMID:19056102, GO:0005524=PMID:9880533, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_25192, GO:0043231=PMID:2440675, GO:0051607=PMID:19923450, GO:0005737=PMID:9880533, GO:0006139=PMID:2440675, GO:0006955=GO_REF:0000002, GO:0060337=Reactome:REACT_25162, GO:0016740=GO_REF:0000002, GO:0060333=Reactome:REACT_25078, GO:0045071=PMID:19056102, GO:0060700=PMID:19923450} Q9Y6K5 2'-5'-oligoadenylate synthase 3 protein 20130415 {GO:0005515=IPI, GO:0003725=IDA, GO:0001730=IDA, GO:0019221=TAS, GO:0005634=IEA, GO:0009615=IDA, GO:0005524=IDA, GO:0046872=IEA, GO:0005829=TAS, GO:0043231=TAS, GO:0051607=IDA, GO:0005737=IDA, GO:0006139=TAS, GO:0006955=IEA, GO:0060337=TAS, GO:0016740=IEA, GO:0060333=TAS, GO:0045071=IDA, GO:0060700=IDA} cytokine-mediated signaling pathway, defense response to virus, immune response, interferon-gamma-mediated signaling pathway, negative regulation of viral genome replication, nucleobase-containing compound metabolic process, regulation of ribonuclease activity, response to virus, type I interferon-mediated signaling pathway cytoplasm, cytosol, intracellular membrane-bounded organelle, nucleus 2'-5'-oligoadenylate synthetase activity, ATP binding, double-stranded RNA binding, metal ion binding, protein binding, transferase activity Human UniProtKB:Q8IY81 OASL Reactome UniProtKB {GO:0003725=PMID:9826176, GO:0001730=PMID:9826176, GO:0019221=Reactome:REACT_25229, GO:0005730=PMID:9826176, GO:0009615=PMID:20074559, GO:0005524=GO_REF:0000002, GO:0003677=PMID:9826176, GO:0005829=Reactome:REACT_25192, GO:0046966=PMID:7776974, GO:0008150=GO_REF:0000015, GO:0051607=GO_REF:0000037, GO:0005737=PMID:9826176, GO:0060337=Reactome:REACT_25162, GO:0060333=Reactome:REACT_25078, GO:0045071=PMID:18931074} Q15646 2'-5'-oligoadenylate synthase-like protein protein 20130228 {GO:0003725=IDA, GO:0001730=IDA, GO:0019221=TAS, GO:0005730=IDA, GO:0009615=IDA, GO:0005524=IEA, GO:0003677=IDA, GO:0005829=TAS, GO:0046966=TAS, GO:0008150=ND, GO:0051607=IEA, GO:0005737=IDA, GO:0060337=TAS, GO:0060333=TAS, GO:0045071=IDA} biological_process, cytokine-mediated signaling pathway, defense response to virus, interferon-gamma-mediated signaling pathway, negative regulation of viral genome replication, response to virus, type I interferon-mediated signaling pathway cytoplasm, cytosol, nucleolus 2'-5'-oligoadenylate synthetase activity, ATP binding, DNA binding, double-stranded RNA binding, thyroid hormone receptor binding Human OAT Reactome UniProtKB {GO:0005739=PMID:2793865, GO:0034641=Reactome:REACT_13, GO:0005759=Reactome:REACT_189, GO:0004587=Reactome:REACT_189, GO:0055129=GO_REF:0000041, GO:0030170=GO_REF:0000002, GO:0008652=Reactome:REACT_238, GO:0044281=Reactome:REACT_111217, GO:0007601=PMID:2793865, GO:0034214=PMID:97454792} P04181 Ornithine aminotransferase, mitochondrial protein 20130213 {GO:0005739=TAS, GO:0034641=TAS, GO:0005759=TAS, GO:0004587=EXP, GO:0055129=IEA, GO:0030170=IEA, GO:0008652=TAS, GO:0044281=TAS, GO:0007601=TAS, GO:0034214=IDA} L-proline biosynthetic process, cellular amino acid biosynthetic process, cellular nitrogen compound metabolic process, protein hexamerization, small molecule metabolic process, visual perception mitochondrial matrix, mitochondrion ornithine-oxo-acid transaminase activity, pyridoxal phosphate binding Human OAZ1 Reactome UniProtKB {GO:0034641=Reactome:REACT_13, GO:0008073=GO_REF:0000019, GO:0006596=PMID:7813017, GO:0006521=Reactome:REACT_13565, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_13759} P54368 Ornithine decarboxylase antizyme 1 protein 20130301 {GO:0034641=TAS, GO:0008073=IEA, GO:0006596=TAS, GO:0006521=TAS, GO:0044281=TAS, GO:0005829=TAS} cellular nitrogen compound metabolic process, polyamine biosynthetic process, regulation of cellular amino acid metabolic process, small molecule metabolic process cytosol ornithine decarboxylase inhibitor activity Human OAZ2 Reactome UniProtKB {GO:0034641=Reactome:REACT_13, GO:0008073=GO_REF:0000019, GO:0006521=Reactome:REACT_13565, GO:0006595=PMID:9428668, GO:0005634=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_13759} O95190 Ornithine decarboxylase antizyme 2 protein 20130301 {GO:0034641=TAS, GO:0008073=IEA, GO:0006521=TAS, GO:0006595=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0005829=TAS} cellular nitrogen compound metabolic process, polyamine metabolic process, regulation of cellular amino acid metabolic process, small molecule metabolic process cytosol, nucleus ornithine decarboxylase inhibitor activity Human OAZ3 Reactome UniProtKB {GO:0034641=Reactome:REACT_13, GO:0008073=GO_REF:0000002, GO:0005737=GO_REF:0000019, GO:0006521=Reactome:REACT_13565, GO:0005634=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0007283=PMID:10781085, GO:0005829=Reactome:REACT_13759} Q9UMX2 Ornithine decarboxylase antizyme 3 protein 20130301 {GO:0034641=TAS, GO:0008073=IEA, GO:0005737=IEA, GO:0006521=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0007283=TAS, GO:0005829=TAS} cellular nitrogen compound metabolic process, regulation of cellular amino acid metabolic process, small molecule metabolic process, spermatogenesis cytoplasm, cytosol, nucleus ornithine decarboxylase inhibitor activity Human OBFC1 HPA UniProtKB {GO:0005515=PMID:19648609, GO:0070188=GO_REF:0000019, GO:0003697=GO_REF:0000024, GO:0000723=PMID:19854130, GO:0045740=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0010833=PMID:19648609, GO:0005634=GO_REF:0000052, GO:0045111=GO_REF:0000052, GO:0043047=PMID:19648609, GO:0000784=PMID:19648609, GO:0043231=GO_REF:0000052} Q9H668 CST complex subunit STN1 protein 20120912 {GO:0005515=IPI, GO:0070188=IEA, GO:0003697=ISS, GO:0000723=IMP, GO:0045740=ISS, GO:0005730=IDA, GO:0010833=IMP, GO:0005634=IDA, GO:0045111=IDA, GO:0043047=IDA, GO:0000784=IDA, GO:0043231=IDA} positive regulation of DNA replication, telomere maintenance, telomere maintenance via telomere lengthening Stn1-Ten1 complex, intermediate filament cytoskeleton, intracellular membrane-bounded organelle, nuclear chromosome, telomeric region, nucleolus, nucleus protein binding, single-stranded DNA binding, single-stranded telomeric DNA binding Human OBP2A PINC UniProtKB {GO:0007608=GO_REF:0000037, GO:0007606=PMID:10607840, GO:0006810=GO_REF:0000037, GO:0005549=PMID:10607840, GO:0005576=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0050896=GO_REF:0000037} Q9NY56 Odorant-binding protein 2a protein 20050308 {GO:0007608=IEA, GO:0007606=TAS, GO:0006810=IEA, GO:0005549=NAS, GO:0005576=IEA, GO:0005575=ND, GO:0050896=IEA} response to stimulus, sensory perception of chemical stimulus, sensory perception of smell, transport cellular_component, extracellular region odorant binding Human OBP2B PINC UniProtKB {GO:0007608=PMID:10607840, GO:0007635=PMID:10607840, GO:0006810=GO_REF:0000037, GO:0005549=PMID:10607840, GO:0005576=GO_REF:0000039, GO:0005575=GO_REF:0000015} Q9NPH6 Odorant-binding protein 2b protein 20030904 {GO:0007608=NAS, GO:0007635=TAS, GO:0006810=IEA, GO:0005549=NAS, GO:0005576=IEA, GO:0005575=ND} chemosensory behavior, sensory perception of smell, transport cellular_component, extracellular region odorant binding Human OBSCN BHF-UCL UniProtKB {GO:0005515=PMID:11448995, GO:0051056=Reactome:REACT_11051, GO:0005516=GO_REF:0000037, GO:0030018=PMID:11717165, GO:0048011=Reactome:REACT_13776, GO:0035023=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0045214=PMID:18782775, GO:0030506=PMID:18782775, GO:0006915=Reactome:REACT_13638, GO:0007275=GO_REF:0000037, GO:0030016=PMID:11717165, GO:0097190=Reactome:REACT_13720, GO:0005524=GO_REF:0000037, GO:0031430=PMID:11717165, GO:0046872=GO_REF:0000037, GO:0031432=PMID:11717165, GO:0005829=Reactome:REACT_19216, GO:0005622=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0004674=GO_REF:0000037, GO:0004713=GO_REF:0000002, GO:0008307=PMID:11717165, GO:0005089=GO_REF:0000002} Q5VST9 Obscurin protein 20120615 {GO:0005515=IPI, GO:0051056=TAS, GO:0005516=IEA, GO:0030018=ISS, GO:0048011=TAS, GO:0035023=IEA, GO:0007264=TAS, GO:0045214=TAS, GO:0030506=IPI, GO:0006915=TAS, GO:0007275=IEA, GO:0030016=NAS, GO:0097190=TAS, GO:0005524=IEA, GO:0031430=ISS, GO:0046872=IEA, GO:0031432=IPI, GO:0005829=TAS, GO:0005622=IEA, GO:0005543=IEA, GO:0004674=IEA, GO:0004713=IEA, GO:0008307=NAS, GO:0005089=IEA} apoptotic process, apoptotic signaling pathway, multicellular organismal development, neurotrophin TRK receptor signaling pathway, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, sarcomere organization, small GTPase mediated signal transduction M band, Z disc, cytosol, intracellular, myofibril ATP binding, Rho guanyl-nucleotide exchange factor activity, ankyrin binding, calmodulin binding, metal ion binding, phospholipid binding, protein binding, protein serine/threonine kinase activity, protein tyrosine kinase activity, structural constituent of muscle, titin binding Human OBSL1 BHF-UCL UniProtKB {GO:0048471=PMID:17289344, GO:0030018=PMID:17289344, GO:0005794=GO_REF:0000039, GO:0014704=PMID:17289344, GO:0007010=PMID:17289344, GO:0055003=PMID:17289344, GO:0031430=PMID:17289344, GO:0008093=PMID:17289344} O75147 Obscurin-like protein 1 protein 20080609 {GO:0048471=TAS, GO:0030018=TAS, GO:0005794=IEA, GO:0014704=TAS, GO:0007010=NAS, GO:0055003=IEP, GO:0031430=TAS, GO:0008093=NAS} cardiac myofibril assembly, cytoskeleton organization Golgi apparatus, M band, Z disc, intercalated disc, perinuclear region of cytoplasm cytoskeletal adaptor activity Human OCA2 GOC UniProtKB {GO:0005515=PMID:19116314, GO:0033162=PMID:19116314, GO:0005215=PMID:8421497, GO:0005302=PMID:7601462, GO:0006726=PMID:8421497, GO:0008283=GO_REF:0000019, GO:0007286=GO_REF:0000019, GO:0030318=GO_REF:0000019, GO:0005765=PMID:19116314, GO:0005737=PMID:7601462, GO:0042438=GO_REF:0000019, GO:0005789=PMID:19116314, GO:0015828=PMID:7601462, GO:0016021=GO_REF:0000037, GO:0010008=PMID:19116314} Q04671 P protein protein 20130413 {GO:0005515=IPI, GO:0033162=IDA, GO:0005215=TAS, GO:0005302=TAS, GO:0006726=TAS, GO:0008283=IEA, GO:0007286=IEA, GO:0030318=IEA, GO:0005765=IDA, GO:0005737=TAS, GO:0042438=IEA, GO:0005789=IDA, GO:0015828=TAS, GO:0016021=IEA, GO:0010008=IDA} cell proliferation, eye pigment biosynthetic process, melanin biosynthetic process, melanocyte differentiation, spermatid development, tyrosine transport cytoplasm, endoplasmic reticulum membrane, endosome membrane, integral to membrane, lysosomal membrane, melanosome membrane L-tyrosine transmembrane transporter activity, protein binding, transporter activity Human OCEL1 null null {} null null null null {} null null null OCIAD1 IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0005739=GO_REF:0000019, GO:0005768=GO_REF:0000039} Q9NX40 OCIA domain-containing protein 1 protein 20130415 {GO:0005515=IPI, GO:0005739=IEA, GO:0005768=IEA} endosome, mitochondrion protein binding Human UniProtKB:P17544 OCIAD2 UniProtKB UniProtKB {GO:0005743=GO_REF:0000019, GO:0005768=GO_REF:0000039} Q56VL3 OCIA domain-containing protein 2 protein 20130413 {GO:0005743=IEA, GO:0005768=IEA} endosome, mitochondrial inner membrane Human UniProtKB-SubCell:SL-0101 OCLN HPA UniProtKB {GO:0005515=PMID:19332538, GO:0030054=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0006915=Reactome:REACT_578, GO:0016327=GO_REF:0000019, GO:0045216=PMID:20164257, GO:0006921=Reactome:REACT_995, GO:0016324=GO_REF:0000019, GO:0006461=PMID:10749869, GO:0005198=GO_REF:0000002, GO:0005911=PMID:19332538, GO:0016021=GO_REF:0000037, GO:0005923=PMID:20164257} Q16625 Occludin protein 20080818 {GO:0005515=IPI, GO:0030054=IDA, GO:0005886=IDA, GO:0006915=TAS, GO:0016327=IEA, GO:0045216=IMP, GO:0006921=TAS, GO:0016324=IEA, GO:0006461=TAS, GO:0005198=IEA, GO:0005911=IDA, GO:0016021=IEA, GO:0005923=IDA} apoptotic process, cell-cell junction organization, cellular component disassembly involved in execution phase of apoptosis, protein complex assembly apical plasma membrane, apicolateral plasma membrane, cell junction, cell-cell junction, integral to membrane, plasma membrane, tight junction protein binding, structural molecule activity Human OCM UniProtKB UniProtKB {GO:0005509=PMID:8354278} P0CE72 Oncomodulin-1 protein 20100419 {GO:0005509=NAS} calcium ion binding Human OCM2 UniProtKB UniProtKB {GO:0005509=PMID:8354278} P0CE71 Putative oncomodulin-2 protein 20100419 {GO:0005509=NAS} calcium ion binding Human OCRL GOC UniProtKB {GO:0005802=PMID:12915445, GO:0005515=PMID:22543976, GO:0006629=PMID:1321346, GO:0043647=Reactome:REACT_150352, GO:0005886=PMID:12915445, GO:0007264=Reactome:REACT_11044, GO:0030136=PMID:21233288, GO:0005634=PMID:12915445, GO:0044281=Reactome:REACT_111217, GO:0032855=PMID:12915445, GO:0005829=Reactome:REACT_150347, GO:0005737=PMID:12915445, GO:0032314=PMID:12915445, GO:0030670=GO_REF:0000039, GO:0030675=PMID:12915445, GO:0051056=Reactome:REACT_11051, GO:0005795=PMID:1840503, GO:0006661=Reactome:REACT_120836, GO:0052745=PMID:1321346, GO:0005798=PMID:1840503, GO:0001701=GO_REF:0000019, GO:0048365=PMID:12915445, GO:0004439=GO_REF:0000003, GO:0042384=PMID:22228094, GO:0005905=GO_REF:0000039, GO:0031901=GO_REF:0000039, GO:0046856=GO_REF:0000019, GO:0006644=Reactome:REACT_121175, GO:0005769=PMID:21233288, GO:0001750=PMID:22543976} Q01968 Inositol polyphosphate 5-phosphatase OCRL-1 protein 20130413 {GO:0005802=IDA, GO:0005515=IPI, GO:0006629=NAS, GO:0043647=TAS, GO:0005886=IDA, GO:0007264=TAS, GO:0030136=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0032855=IDA, GO:0005829=TAS, GO:0005737=IDA, GO:0032314=IDA, GO:0030670=IEA, GO:0030675=IDA, GO:0051056=TAS, GO:0005795=TAS, GO:0006661=TAS, GO:0052745=NAS, GO:0005798=TAS, GO:0001701=IEA, GO:0048365=IPI, GO:0004439=IEA, GO:0042384=IMP, GO:0005905=IEA, GO:0031901=IEA, GO:0046856=IEA, GO:0006644=TAS, GO:0005769=IDA, GO:0001750=IDA} cilium assembly, in utero embryonic development, inositol phosphate metabolic process, lipid metabolic process, phosphatidylinositol biosynthetic process, phosphatidylinositol dephosphorylation, phospholipid metabolic process, positive regulation of Rac GTPase activity, regulation of Rac GTPase activity, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction, small molecule metabolic process Golgi stack, Golgi-associated vesicle, clathrin-coated vesicle, coated pit, cytoplasm, cytosol, early endosome, early endosome membrane, nucleus, phagocytic vesicle membrane, photoreceptor outer segment, plasma membrane, trans-Golgi network Rac GTPase activator activity, Rac GTPase binding, inositol phosphate phosphatase activity, phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, protein binding Human ODAM HGNC UniProtKB {GO:0042475=PMID:16674676, GO:0005576=Reactome:REACT_75905, GO:0043205=PMID:14647039, GO:0031214=GO_REF:0000037} A1E959 Odontogenic ameloblast-associated protein protein 20090803 {GO:0042475=IEP, GO:0005576=TAS, GO:0043205=IDA, GO:0031214=IEA} biomineral tissue development, odontogenesis of dentin-containing tooth extracellular region, fibril Human ODC1 Reactome UniProtKB {GO:0034641=Reactome:REACT_13, GO:0008284=GO_REF:0000019, GO:0006596=GO_REF:0000029, GO:0004586=PMID:2317811, GO:0001822=GO_REF:0000019, GO:0006521=Reactome:REACT_13565, GO:0006595=Reactome:REACT_14820, GO:0033387=GO_REF:0000041, GO:0044281=Reactome:REACT_111217, GO:0005575=GO_REF:0000015, GO:0009615=PMID:16548883, GO:0005829=Reactome:REACT_13759} P11926 Ornithine decarboxylase protein 20130213 {GO:0034641=TAS, GO:0008284=IEA, GO:0006596=NAS, GO:0004586=TAS, GO:0001822=IEA, GO:0006521=TAS, GO:0006595=TAS, GO:0033387=IEA, GO:0044281=TAS, GO:0005575=ND, GO:0009615=IEP, GO:0005829=TAS} cellular nitrogen compound metabolic process, kidney development, polyamine biosynthetic process, polyamine metabolic process, positive regulation of cell proliferation, putrescine biosynthetic process from ornithine, regulation of cellular amino acid metabolic process, response to virus, small molecule metabolic process cellular_component, cytosol ornithine decarboxylase activity Human ODF1 UniProtKB UniProtKB {GO:0005198=GO_REF:0000029, GO:0019904=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000029, GO:0001520=GO_REF:0000029, GO:0030154=GO_REF:0000037} Q14990 Outer dense fiber protein 1 protein 20021104 {GO:0005198=NAS, GO:0019904=IEA, GO:0007275=IEA, GO:0007283=NAS, GO:0001520=NAS, GO:0030154=IEA} cell differentiation, multicellular organismal development, spermatogenesis outer dense fiber protein domain specific binding, structural molecule activity Human ODF2 ENSEMBL UniProtKB {GO:0005515=PMID:16980960, GO:0005813=PMID:21399614, GO:0005814=GO_REF:0000019, GO:0005874=GO_REF:0000037, GO:0007286=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0001520=GO_REF:0000019, GO:0005829=Reactome:REACT_15470, GO:0005929=GO_REF:0000039, GO:0000922=GO_REF:0000039, GO:0005198=PMID:10072582, GO:0000086=Reactome:REACT_2203, GO:0000278=Reactome:REACT_152} Q5T4C7 Outer dense fiber protein 2 protein 20130413 {GO:0005515=IPI, GO:0005813=IDA, GO:0005814=IEA, GO:0005874=IEA, GO:0007286=IEA, GO:0007275=IEA, GO:0001520=IEA, GO:0005829=TAS, GO:0005929=IEA, GO:0000922=IEA, GO:0005198=TAS, GO:0000086=TAS, GO:0000278=TAS} G2/M transition of mitotic cell cycle, mitotic cell cycle, multicellular organismal development, spermatid development centriole, centrosome, cilium, cytosol, microtubule, outer dense fiber, spindle pole protein binding, structural molecule activity Human Ensembl:ENSRNOP00000041336 ODF2L UniProtKB UniProtKB {GO:0005813=PMID:21399614} Q9ULJ1 Outer dense fiber protein 2-like protein 20110517 {GO:0005813=IDA} centrosome Human ODF3 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0001520=GO_REF:0000019, GO:0030154=GO_REF:0000037} Q96PU9 Outer dense fiber protein 3 protein 20130413 {GO:0005737=IEA, GO:0007275=IEA, GO:0007283=IEA, GO:0001520=IEA, GO:0030154=IEA} cell differentiation, multicellular organismal development, spermatogenesis cytoplasm, outer dense fiber Human UniProtKB-SubCell:SL-0086 ODF3L2 UniProtKB UniProtKB {GO:0005881=PMID:23264731} Q3SX64 Outer dense fiber protein 3-like protein 2 protein 20130311 {GO:0005881=IDA} cytoplasmic microtubule Human ODF4 ENSEMBL UniProtKB {GO:0007275=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0001520=GO_REF:0000019, GO:0030154=GO_REF:0000037} Q2M2E3 Outer dense fiber protein 4 protein 20130413 {GO:0007275=IEA, GO:0016021=IEA, GO:0007283=IEA, GO:0001520=IEA, GO:0030154=IEA} cell differentiation, multicellular organismal development, spermatogenesis integral to membrane, outer dense fiber Human Ensembl:ENSMUSP00000040050 OFCC1 ENSEMBL UniProtKB {GO:0048471=GO_REF:0000019, GO:0005783=GO_REF:0000019, GO:0015630=GO_REF:0000019, GO:0005829=GO_REF:0000019} E9PHR2 Orofacial cleft 1 candidate gene 1 protein protein 20130413 {GO:0048471=IEA, GO:0005783=IEA, GO:0015630=IEA, GO:0005829=IEA} cytosol, endoplasmic reticulum, microtubule cytoskeleton, perinuclear region of cytoplasm Human Ensembl:ENSMUSP00000062217 OFD1 HPA UniProtKB {GO:0005515=PMID:21988832, GO:0005813=PMID:21399614, GO:0035083=GO_REF:0000019, GO:0043015=GO_REF:0000024, GO:0007099=GO_REF:0000024, GO:0005814=PMID:20230748, GO:0043014=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0005829=Reactome:REACT_15470, GO:0060287=GO_REF:0000024, GO:0005929=PMID:20230748, GO:0007067=GO_REF:0000024, GO:0000086=Reactome:REACT_2203, GO:0015630=GO_REF:0000052, GO:0060271=GO_REF:0000024, GO:0090307=GO_REF:0000024, GO:0005932=PMID:20230748, GO:0000278=Reactome:REACT_152} O75665 Oral-facial-digital syndrome 1 protein protein 20111111 {GO:0005515=IPI, GO:0005813=IDA, GO:0035083=IEA, GO:0043015=ISS, GO:0007099=ISS, GO:0005814=IDA, GO:0043014=ISS, GO:0005634=IEA, GO:0005829=TAS, GO:0060287=ISS, GO:0005929=IDA, GO:0007067=ISS, GO:0000086=TAS, GO:0015630=IDA, GO:0060271=ISS, GO:0090307=ISS, GO:0005932=IDA, GO:0000278=TAS} G2/M transition of mitotic cell cycle, centriole replication, cilium axoneme assembly, cilium morphogenesis, epithelial cilium movement involved in determination of left/right asymmetry, mitosis, mitotic cell cycle, spindle assembly involved in mitosis centriole, centrosome, cilium, cytosol, microtubule basal body, microtubule cytoskeleton, nucleus alpha-tubulin binding, gamma-tubulin binding, protein binding Human OGDH HPA UniProtKB {GO:0006099=Reactome:REACT_1785, GO:0021695=GO_REF:0000019, GO:0051087=GO_REF:0000019, GO:0006091=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0021860=GO_REF:0000019, GO:0004591=GO_REF:0000024, GO:0006096=GO_REF:0000037, GO:0022028=GO_REF:0000019, GO:0021794=GO_REF:0000019, GO:0005739=GO_REF:0000052, GO:0034641=Reactome:REACT_13, GO:0031072=GO_REF:0000019, GO:0006104=GO_REF:0000019, GO:0005759=Reactome:REACT_1865, GO:0006103=GO_REF:0000019, GO:0006554=Reactome:REACT_1298, GO:0045252=GO_REF:0000019, GO:0034602=GO_REF:0000019, GO:0031966=GO_REF:0000024, GO:0030976=GO_REF:0000002, GO:0006734=GO_REF:0000019, GO:0021766=GO_REF:0000019, GO:0021756=GO_REF:0000019, GO:0061034=GO_REF:0000019} Q02218 2-oxoglutarate dehydrogenase, mitochondrial protein 20100326 {GO:0006099=TAS, GO:0021695=IEA, GO:0051087=IEA, GO:0006091=ISS, GO:0044281=TAS, GO:0021860=IEA, GO:0004591=ISS, GO:0006096=IEA, GO:0022028=IEA, GO:0021794=IEA, GO:0005739=IDA, GO:0034641=TAS, GO:0031072=IEA, GO:0006104=IEA, GO:0005759=TAS, GO:0006103=IEA, GO:0006554=TAS, GO:0045252=IEA, GO:0034602=IEA, GO:0031966=ISS, GO:0030976=IEA, GO:0006734=IEA, GO:0021766=IEA, GO:0021756=IEA, GO:0061034=IEA} 2-oxoglutarate metabolic process, NADH metabolic process, cellular nitrogen compound metabolic process, cerebellar cortex development, generation of precursor metabolites and energy, glycolysis, hippocampus development, lysine catabolic process, olfactory bulb mitral cell layer development, pyramidal neuron development, small molecule metabolic process, striatum development, succinyl-CoA metabolic process, tangential migration from the subventricular zone to the olfactory bulb, thalamus development, tricarboxylic acid cycle mitochondrial matrix, mitochondrial membrane, mitochondrion, oxoglutarate dehydrogenase complex chaperone binding, heat shock protein binding, oxoglutarate dehydrogenase (NAD+) activity, oxoglutarate dehydrogenase (succinyl-transferring) activity, thiamine pyrophosphate binding Human OGDHL IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0006099=GO_REF:0000002, GO:0005759=GO_REF:0000039, GO:0030976=GO_REF:0000002, GO:0004591=GO_REF:0000002, GO:0006096=GO_REF:0000037} Q9ULD0 2-oxoglutarate dehydrogenase-like, mitochondrial protein 20130415 {GO:0005515=IPI, GO:0006099=IEA, GO:0005759=IEA, GO:0030976=IEA, GO:0004591=IEA, GO:0006096=IEA} glycolysis, tricarboxylic acid cycle mitochondrial matrix oxoglutarate dehydrogenase (succinyl-transferring) activity, protein binding, thiamine pyrophosphate binding Human UniProtKB:P40763 OGFOD1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0031418=GO_REF:0000037, GO:0005506=GO_REF:0000002, GO:0016706=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0016702=GO_REF:0000037} Q8N543 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1 protein 20130413 {GO:0005737=IEA, GO:0031418=IEA, GO:0005506=IEA, GO:0016706=IEA, GO:0005634=IEA, GO:0016702=IEA} cytoplasm, nucleus L-ascorbic acid binding, iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Human UniProtKB-SubCell:SL-0086 OGFOD2 UniProtKB UniProtKB {GO:0031418=GO_REF:0000037, GO:0005506=GO_REF:0000002, GO:0016706=GO_REF:0000002, GO:0016702=GO_REF:0000037} Q6N063 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 protein 20130413 {GO:0031418=IEA, GO:0005506=IEA, GO:0016706=IEA, GO:0016702=IEA} L-ascorbic acid binding, iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Human UniProtKB-KW:KW-0847 OGFR GOC UniProtKB {GO:0005737=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0004872=GO_REF:0000002, GO:0038003=PMID:10677613, GO:0005575=GO_REF:0000015, GO:0001558=PMID:10677613, GO:0004985=PMID:10677613} Q9NZT2 Opioid growth factor receptor protein 20130413 {GO:0005737=IEA, GO:0016020=IEA, GO:0005634=IEA, GO:0004872=IEA, GO:0038003=NAS, GO:0005575=ND, GO:0001558=NAS, GO:0004985=NAS} opioid receptor signaling pathway, regulation of cell growth cellular_component, cytoplasm, membrane, nucleus opioid receptor activity, receptor activity Human OGFRL1 InterPro UniProtKB {GO:0016020=GO_REF:0000002, GO:0004872=GO_REF:0000002} Q5TC84 Opioid growth factor receptor-like protein 1 protein 20130413 {GO:0016020=IEA, GO:0004872=IEA} membrane receptor activity Human InterPro:IPR006757 OGG1 HPA UniProtKB {GO:0008017=GO_REF:0000019, GO:0005515=PMID:15518571, GO:0045471=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0003824=GO_REF:0000002, GO:0016363=PMID:17148573, GO:0005739=GO_REF:0000039, GO:0008534=PMID:9190902, GO:0033158=PMID:17148573, GO:0071276=GO_REF:0000019, GO:0032355=GO_REF:0000019, GO:0006979=PMID:17148573, GO:0009314=PMID:17148573, GO:0002526=GO_REF:0000019, GO:0006355=PMID:8621488, GO:0042493=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0034039=GO_REF:0000019, GO:0051593=GO_REF:0000019, GO:0003684=GO_REF:0000019, GO:0006281=Reactome:REACT_216, GO:0004519=PMID:9223305, GO:0016607=PMID:17148573, GO:0045007=Reactome:REACT_2176, GO:0006284=Reactome:REACT_1104, GO:0006285=Reactome:REACT_804, GO:0005654=Reactome:REACT_1843, GO:0006289=GO_REF:0000002} O15527 N-glycosylase/DNA lyase protein 20120912 {GO:0008017=IEA, GO:0005515=IPI, GO:0045471=IEA, GO:0005634=IDA, GO:0003824=IEA, GO:0016363=IDA, GO:0005739=IEA, GO:0008534=TAS, GO:0033158=IDA, GO:0071276=IEA, GO:0032355=IEA, GO:0006979=IDA, GO:0009314=IDA, GO:0002526=IEA, GO:0006355=IMP, GO:0042493=IEA, GO:0005730=IDA, GO:0034039=IEA, GO:0051593=IEA, GO:0003684=IEA, GO:0006281=TAS, GO:0004519=TAS, GO:0016607=IDA, GO:0045007=TAS, GO:0006284=TAS, GO:0006285=TAS, GO:0005654=TAS, GO:0006289=IEA} DNA repair, acute inflammatory response, base-excision repair, base-excision repair, AP site formation, cellular response to cadmium ion, depurination, nucleotide-excision repair, regulation of protein import into nucleus, translocation, regulation of transcription, DNA-dependent, response to drug, response to estradiol stimulus, response to ethanol, response to folic acid, response to oxidative stress, response to radiation mitochondrion, nuclear matrix, nuclear speck, nucleolus, nucleoplasm, nucleus 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity, catalytic activity, damaged DNA binding, endonuclease activity, microtubule binding, oxidized purine nucleobase lesion DNA N-glycosylase activity, protein binding NOT Human OGN IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0005796=Reactome:REACT_121317, GO:0005975=Reactome:REACT_474, GO:0005578=GO_REF:0000039, GO:0048662=GO_REF:0000024, GO:0005576=Reactome:REACT_121303, GO:0044281=Reactome:REACT_111217, GO:0042339=Reactome:REACT_121288, GO:0018146=Reactome:REACT_121120, GO:0042340=Reactome:REACT_121313, GO:0008083=GO_REF:0000037, GO:0030203=Reactome:REACT_121315, GO:0043202=Reactome:REACT_121303} P20774 Mimecan protein 20130415 {GO:0005515=IPI, GO:0005796=TAS, GO:0005975=TAS, GO:0005578=IEA, GO:0048662=ISS, GO:0005576=TAS, GO:0044281=TAS, GO:0042339=TAS, GO:0018146=TAS, GO:0042340=TAS, GO:0008083=IEA, GO:0030203=TAS, GO:0043202=TAS} carbohydrate metabolic process, glycosaminoglycan metabolic process, keratan sulfate biosynthetic process, keratan sulfate catabolic process, keratan sulfate metabolic process, negative regulation of smooth muscle cell proliferation, small molecule metabolic process Golgi lumen, extracellular region, lysosomal lumen, proteinaceous extracellular matrix growth factor activity, protein binding Human UniProtKB:P46108 OGT GOC UniProtKB {GO:0005515=PMID:21295698, GO:0035020=PMID:18288188, GO:0005886=PMID:18288188, GO:0071300=PMID:19377461, GO:0016262=PMID:23222540, GO:0080182=PMID:23353889, GO:0005634=GO_REF:0000052, GO:0005829=PMID:21285374, GO:0005739=GO_REF:0000039, GO:0006493=PMID:23222540, GO:0030854=PMID:19377461, GO:0043996=PMID:20018852, GO:0045944=PMID:23222540, GO:0000123=PMID:20018852, GO:0043995=PMID:20018852, GO:0008375=PMID:9083068, GO:0032868=PMID:18288188, GO:0005813=GO_REF:0000052, GO:0007584=PMID:9083068, GO:0048015=PMID:18288188, GO:0046626=PMID:18288188, GO:0005730=GO_REF:0000052, GO:0005547=PMID:18288188, GO:0006915=GO_REF:0000037, GO:0006917=PMID:20824293, GO:0043085=PMID:19377461, GO:0045862=PMID:21285374, GO:0043981=PMID:20018852, GO:0007165=PMID:9083067, GO:0006110=PMID:22923583, GO:0043982=PMID:20018852, GO:0051571=PMID:19377461, GO:0070688=PMID:19377461, GO:0043984=PMID:20018852, GO:0046972=PMID:20018852, GO:0008047=PMID:19377461} O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit protein 20130413 {GO:0005515=IPI, GO:0035020=IDA, GO:0005886=IDA, GO:0071300=IMP, GO:0016262=IDA, GO:0080182=IMP, GO:0005634=IDA, GO:0005829=IDA, GO:0005739=IEA, GO:0006493=IDA, GO:0030854=IMP, GO:0043996=IDA, GO:0045944=IDA, GO:0000123=IDA, GO:0043995=IDA, GO:0008375=TAS, GO:0032868=IDA, GO:0005813=IDA, GO:0007584=TAS, GO:0048015=IDA, GO:0046626=IDA, GO:0005730=IDA, GO:0005547=IDA, GO:0006915=IEA, GO:0006917=IDA, GO:0043085=IDA, GO:0045862=IDA, GO:0043981=IDA, GO:0007165=TAS, GO:0006110=IDA, GO:0043982=IDA, GO:0051571=IDA, GO:0070688=IDA, GO:0043984=IDA, GO:0046972=IDA, GO:0008047=IDA} apoptotic process, cellular response to retinoic acid, histone H3-K4 trimethylation, histone H4-K16 acetylation, histone H4-K5 acetylation, histone H4-K8 acetylation, induction of apoptosis, phosphatidylinositol-mediated signaling, positive regulation of catalytic activity, positive regulation of granulocyte differentiation, positive regulation of histone H3-K4 methylation, positive regulation of proteolysis, positive regulation of transcription from RNA polymerase II promoter, protein O-linked glycosylation, regulation of Rac protein signal transduction, regulation of glycolysis, regulation of insulin receptor signaling pathway, response to insulin stimulus, response to nutrient, signal transduction MLL5-L complex, centrosome, cytosol, histone acetyltransferase complex, mitochondrion, nucleolus, nucleus, plasma membrane acetylglucosaminyltransferase activity, enzyme activator activity, histone acetyltransferase activity (H4-K16 specific), histone acetyltransferase activity (H4-K5 specific), histone acetyltransferase activity (H4-K8 specific), phosphatidylinositol-3,4,5-trisphosphate binding, protein N-acetylglucosaminyltransferase activity, protein binding Human OIP5 IntAct UniProtKB {GO:0005515=PMID:12620389, GO:0034080=Reactome:REACT_22186, GO:0007067=GO_REF:0000037, GO:0015030=PMID:17284516, GO:0007154=PMID:9466265, GO:0010369=GO_REF:0000019, GO:0006334=Reactome:REACT_22344, GO:0005654=Reactome:REACT_22217, GO:0005634=PMID:17284516, GO:0000785=PMID:17284516, GO:0000775=GO_REF:0000039, GO:0051301=GO_REF:0000037} O43482 Protein Mis18-beta protein 20130415 {GO:0005515=IPI, GO:0034080=TAS, GO:0007067=IEA, GO:0015030=IDA, GO:0007154=NAS, GO:0010369=IEA, GO:0006334=TAS, GO:0005654=TAS, GO:0005634=IDA, GO:0000785=IDA, GO:0000775=IEA, GO:0051301=IEA} CENP-A containing nucleosome assembly at centromere, cell communication, cell division, mitosis, nucleosome assembly Cajal body, chromatin, chromocenter, chromosome, centromeric region, nucleoplasm, nucleus protein binding Human UniProtKB:P04049 OLA1 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0005737=GO_REF:0000054, GO:0006200=PMID:17430889, GO:0016787=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0005525=GO_REF:0000002, GO:0005524=PMID:17430889} Q9NTK5 Obg-like ATPase 1 protein 20130415 {GO:0005515=IPI, GO:0005737=IDA, GO:0006200=IDA, GO:0016787=IEA, GO:0005730=IEA, GO:0005525=IEA, GO:0005524=IDA} ATP catabolic process cytoplasm, nucleolus ATP binding, GTP binding, hydrolase activity, protein binding Human UniProtKB:P04591:PRO_0000038593 OLFM1 IntAct UniProtKB {GO:0005515=PMID:17043677, GO:0030054=GO_REF:0000037, GO:0045202=GO_REF:0000039, GO:0051259=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0007399=PMID:9039501} Q99784 Noelin protein 20130415 {GO:0005515=IPI, GO:0030054=IEA, GO:0045202=IEA, GO:0051259=IEA, GO:0005615=IEA, GO:0007399=TAS} nervous system development, protein oligomerization cell junction, extracellular space, synapse protein binding Human UniProtKB:Q9NRI5 OLFM2 UniProtKB UniProtKB {GO:0030054=GO_REF:0000037, GO:0045202=GO_REF:0000039, GO:0005576=GO_REF:0000039} O95897 Noelin-2 protein 20130413 {GO:0030054=IEA, GO:0045202=IEA, GO:0005576=IEA} cell junction, extracellular region, synapse Human UniProtKB-SubCell:SL-0258 OLFM3 UniProtKB UniProtKB {GO:0005794=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0045202=GO_REF:0000039, GO:0042462=GO_REF:0000019, GO:0005615=GO_REF:0000019} Q96PB7 Noelin-3 protein 20130413 {GO:0005794=IEA, GO:0030054=IEA, GO:0045202=IEA, GO:0042462=IEA, GO:0005615=IEA} eye photoreceptor cell development Golgi apparatus, cell junction, extracellular space, synapse Human UniProtKB-SubCell:SL-0258 OLFM4 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0007155=GO_REF:0000037, GO:0005615=GO_REF:0000039} Q6UX06 Olfactomedin-4 protein 20130413 {GO:0005739=IEA, GO:0007155=IEA, GO:0005615=IEA} cell adhesion extracellular space, mitochondrion Human UniProtKB-SubCell:SL-0173 OLFML2A UniProtKB UniProtKB {GO:0031012=GO_REF:0000019, GO:0030198=GO_REF:0000019, GO:0050840=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0042803=GO_REF:0000019} Q68BL7 Olfactomedin-like protein 2A protein 20130413 {GO:0031012=IEA, GO:0030198=IEA, GO:0050840=IEA, GO:0005576=IEA, GO:0042803=IEA} extracellular matrix organization extracellular matrix, extracellular region extracellular matrix binding, protein homodimerization activity Human UniProtKB-SubCell:SL-0243 OLFML3 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039, GO:0007275=GO_REF:0000037} Q9NRN5 Olfactomedin-like protein 3 protein 20130413 {GO:0005576=IEA, GO:0007275=IEA} multicellular organismal development extracellular region Human UniProtKB-SubCell:SL-0243 OLIG1 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0048663=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8TAK6 Oligodendrocyte transcription factor 1 protein 20130413 {GO:0006355=IEA, GO:0046983=IEA, GO:0005634=IEA, GO:0048663=IEA, GO:0003677=IEA, GO:0006351=IEA} neuron fate commitment, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, protein dimerization activity Human UniProtKB-SubCell:SL-0191 OLIG2 UniProtKB UniProtKB {GO:0021522=GO_REF:0000019, GO:0021530=GO_REF:0000019, GO:0003705=GO_REF:0000019, GO:0042552=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0000122=GO_REF:0000019, GO:0048663=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0042803=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0045665=GO_REF:0000019, GO:0048714=GO_REF:0000019, GO:0071837=GO_REF:0000019} Q13516 Oligodendrocyte transcription factor 2 protein 20130413 {GO:0021522=IEA, GO:0021530=IEA, GO:0003705=IEA, GO:0042552=IEA, GO:0005634=IEA, GO:0000122=IEA, GO:0048663=IEA, GO:0003677=IEA, GO:0042803=IEA, GO:0005737=IEA, GO:0045665=IEA, GO:0048714=IEA, GO:0071837=IEA} myelination, negative regulation of neuron differentiation, negative regulation of transcription from RNA polymerase II promoter, neuron fate commitment, positive regulation of oligodendrocyte differentiation, spinal cord motor neuron differentiation, spinal cord oligodendrocyte cell fate specification cytoplasm, nucleus DNA binding, HMG box domain binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, protein homodimerization activity Human UniProtKB-SubCell:SL-0086 OLIG3 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q7RTU3 Oligodendrocyte transcription factor 3 protein 20130413 {GO:0006355=IEA, GO:0046983=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, protein dimerization activity Human UniProtKB-SubCell:SL-0191 OLR1 Reactome UniProtKB {GO:0008219=GO_REF:0000019, GO:0042542=GO_REF:0000019, GO:0005886=Reactome:REACT_12039, GO:0008015=PMID:9052782, GO:0005576=GO_REF:0000039, GO:0050900=Reactome:REACT_12051, GO:0005041=GO_REF:0000019, GO:0006954=GO_REF:0000019, GO:0016020=PMID:9052782, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:9052782, GO:0042157=GO_REF:0000019, GO:0006508=PMID:9052782, GO:0007159=GO_REF:0000019, GO:0030246=GO_REF:0000002} P78380 Oxidized low-density lipoprotein receptor 1 protein 20130213 {GO:0008219=IEA, GO:0042542=IEA, GO:0005886=TAS, GO:0008015=TAS, GO:0005576=IEA, GO:0050900=TAS, GO:0005041=IEA, GO:0006954=IEA, GO:0016020=TAS, GO:0007596=TAS, GO:0005887=TAS, GO:0042157=IEA, GO:0006508=TAS, GO:0007159=IEA, GO:0030246=IEA} blood circulation, blood coagulation, cell death, inflammatory response, leukocyte cell-cell adhesion, leukocyte migration, lipoprotein metabolic process, proteolysis, response to hydrogen peroxide extracellular region, integral to plasma membrane, membrane, plasma membrane carbohydrate binding, low-density lipoprotein receptor activity Human OMA1 UniProtKB UniProtKB {GO:0006629=PMID:22433842, GO:0031966=PMID:20038677, GO:0034982=GO_REF:0000019, GO:0002024=PMID:22433842, GO:0005743=GO_REF:0000039, GO:0006950=PMID:20038677, GO:0046872=GO_REF:0000037, GO:0097009=PMID:22433842, GO:0010637=PMID:22433842, GO:0016020=GO_REF:0000002, GO:0006508=GO_REF:0000038, GO:0006006=PMID:22433842, GO:0006515=PMID:20038677, GO:0016021=GO_REF:0000037, GO:0004222=PMID:22433842, GO:0042407=GO_REF:0000019} Q96E52 Metalloendopeptidase OMA1, mitochondrial protein 20120329 {GO:0006629=IMP, GO:0031966=IDA, GO:0034982=IEA, GO:0002024=IMP, GO:0005743=IEA, GO:0006950=IDA, GO:0046872=IEA, GO:0097009=IMP, GO:0010637=IMP, GO:0016020=IEA, GO:0006508=IEA, GO:0006006=IMP, GO:0006515=IMP, GO:0016021=IEA, GO:0004222=IMP, GO:0042407=IEA} cristae formation, diet induced thermogenesis, energy homeostasis, glucose metabolic process, lipid metabolic process, misfolded or incompletely synthesized protein catabolic process, mitochondrial protein processing, negative regulation of mitochondrial fusion, proteolysis, response to stress integral to membrane, membrane, mitochondrial inner membrane, mitochondrial membrane metal ion binding, metalloendopeptidase activity Human OMG Reactome UniProtKB {GO:0048011=Reactome:REACT_13776, GO:0005886=Reactome:REACT_13732, GO:0031102=GO_REF:0000019, GO:0048683=GO_REF:0000019, GO:0050771=Reactome:REACT_13815, GO:0031225=GO_REF:0000037, GO:0007155=GO_REF:0000037, GO:0050770=Reactome:REACT_13620, GO:0042802=GO_REF:0000019} P23515 Oligodendrocyte-myelin glycoprotein protein 20130301 {GO:0048011=TAS, GO:0005886=TAS, GO:0031102=IEA, GO:0048683=IEA, GO:0050771=TAS, GO:0031225=IEA, GO:0007155=IEA, GO:0050770=TAS, GO:0042802=IEA} cell adhesion, negative regulation of axonogenesis, neuron projection regeneration, neurotrophin TRK receptor signaling pathway, regulation of axonogenesis, regulation of collateral sprouting of intact axon in response to injury anchored to membrane, plasma membrane identical protein binding Human OMP PINC UniProtKB {GO:0007165=PMID:8790421, GO:0030424=GO_REF:0000019, GO:0007608=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0043025=GO_REF:0000019, GO:0007268=PMID:8790421, GO:0005634=GO_REF:0000019, GO:0004871=GO_REF:0000019, GO:0022008=GO_REF:0000019} P47874 Olfactory marker protein protein 20030904 {GO:0007165=TAS, GO:0030424=IEA, GO:0007608=IEA, GO:0005737=IEA, GO:0043025=IEA, GO:0007268=TAS, GO:0005634=IEA, GO:0004871=IEA, GO:0022008=IEA} neurogenesis, sensory perception of smell, signal transduction, synaptic transmission axon, cytoplasm, neuronal cell body, nucleus signal transducer activity Human ONECUT1 BHF-UCL UniProtKB {GO:0006355=PMID:10491763, GO:0030335=GO_REF:0000019, GO:0005634=GO_REF:0000029, GO:0048536=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0001889=GO_REF:0000019, GO:0042384=GO_REF:0000019, GO:0001077=GO_REF:0000024, GO:0045165=GO_REF:0000019, GO:0007492=GO_REF:0000019, GO:0045944=GO_REF:0000024, GO:0031018=Reactome:REACT_13778, GO:0002064=GO_REF:0000019, GO:0030183=GO_REF:0000019, GO:0001952=GO_REF:0000019, GO:0006006=GO_REF:0000019, GO:0045893=GO_REF:0000029, GO:0030512=GO_REF:0000019} Q9UBC0 Hepatocyte nuclear factor 6 protein 20110311 {GO:0006355=NAS, GO:0030335=IEA, GO:0005634=NAS, GO:0048536=IEA, GO:0043565=IEA, GO:0001889=IEA, GO:0042384=IEA, GO:0001077=ISS, GO:0045165=IEA, GO:0007492=IEA, GO:0045944=ISS, GO:0031018=TAS, GO:0002064=IEA, GO:0030183=IEA, GO:0001952=IEA, GO:0006006=IEA, GO:0045893=NAS, GO:0030512=IEA} B cell differentiation, cell fate commitment, cilium assembly, endocrine pancreas development, endoderm development, epithelial cell development, glucose metabolic process, liver development, negative regulation of transforming growth factor beta receptor signaling pathway, positive regulation of cell migration, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of cell-matrix adhesion, regulation of transcription, DNA-dependent, spleen development nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, sequence-specific DNA binding Human UniProtKB:P70512 ONECUT2 PINC UniProtKB {GO:0003700=GO_REF:0000019, GO:0030335=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0001889=GO_REF:0000019, GO:0042384=GO_REF:0000019, GO:0045165=GO_REF:0000019, GO:0031018=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0002064=GO_REF:0000019, GO:0001952=GO_REF:0000019, GO:0048935=GO_REF:0000019, GO:0009887=PMID:9915796, GO:0030512=GO_REF:0000019} O95948 One cut domain family member 2 protein 20031120 {GO:0003700=IEA, GO:0030335=IEA, GO:0005634=IEA, GO:0006351=IEA, GO:0043565=IEA, GO:0001889=IEA, GO:0042384=IEA, GO:0045165=IEA, GO:0031018=IEA, GO:0045944=IEA, GO:0002064=IEA, GO:0001952=IEA, GO:0048935=IEA, GO:0009887=TAS, GO:0030512=IEA} cell fate commitment, cilium assembly, endocrine pancreas development, epithelial cell development, liver development, negative regulation of transforming growth factor beta receptor signaling pathway, organ morphogenesis, peripheral nervous system neuron development, positive regulation of cell migration, positive regulation of transcription from RNA polymerase II promoter, regulation of cell-matrix adhesion, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human OPA1 GOC UniProtKB {GO:0005515=PMID:20436456, GO:0000287=PMID:11017080, GO:0000266=PMID:12509422, GO:0005743=PMID:20436456, GO:0003924=PMID:11017080, GO:0001843=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0005741=PMID:12504110, GO:0005525=GO_REF:0000037, GO:0030425=PMID:11847212, GO:0006184=PMID:11017080, GO:0005739=PMID:17545159, GO:0005758=PMID:11847212, GO:0008053=PMID:20436456, GO:0090201=PMID:21149567, GO:0019896=PMID:11017080, GO:0007007=PMID:12509422, GO:0007005=PMID:21149567, GO:0016021=GO_REF:0000037, GO:0007601=PMID:11017080, GO:0030061=PMID:12504110, GO:0090398=PMID:17545159} O60313 Dynamin-like 120 kDa protein, mitochondrial protein 20130413 {GO:0005515=IPI, GO:0000287=NAS, GO:0000266=TAS, GO:0005743=NAS, GO:0003924=TAS, GO:0001843=IEA, GO:0006915=IEA, GO:0005741=IDA, GO:0005525=IEA, GO:0030425=ISS, GO:0006184=TAS, GO:0005739=IDA, GO:0005758=ISS, GO:0008053=IMP, GO:0090201=IMP, GO:0019896=TAS, GO:0007007=IDA, GO:0007005=IMP, GO:0016021=IEA, GO:0007601=IMP, GO:0030061=IDA, GO:0090398=IDA} GTP catabolic process, apoptotic process, axon transport of mitochondrion, cellular senescence, inner mitochondrial membrane organization, mitochondrial fission, mitochondrial fusion, mitochondrion organization, negative regulation of release of cytochrome c from mitochondria, neural tube closure, visual perception dendrite, integral to membrane, mitochondrial crista, mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial outer membrane, mitochondrion GTP binding, GTPase activity, magnesium ion binding, protein binding Human OPA3 LIFEdb UniProtKB {GO:0005739=GO_REF:0000054, GO:0007601=PMID:15342707, GO:0050896=GO_REF:0000037} Q9H6K4 Optic atrophy 3 protein protein 20100607 {GO:0005739=IDA, GO:0007601=IMP, GO:0050896=IEA} response to stimulus, visual perception mitochondrion Human OPALIN LIFEdb UniProtKB {GO:0005794=GO_REF:0000054, GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q96PE5 Opalin protein 20100607 {GO:0005794=IDA, GO:0005886=IEA, GO:0016021=IEA} Golgi apparatus, integral to membrane, plasma membrane Human OPCML GOC UniProtKB {GO:0008038=PMID:7891157, GO:0005886=PMID:1333602, GO:0005887=PMID:1333602, GO:0038003=PMID:1333602, GO:0031225=GO_REF:0000037, GO:0007155=GO_REF:0000037, GO:0004985=PMID:1333602} Q14982 Opioid-binding protein/cell adhesion molecule protein 20130413 {GO:0008038=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0038003=TAS, GO:0031225=IEA, GO:0007155=IEA, GO:0004985=TAS} cell adhesion, neuron recognition, opioid receptor signaling pathway anchored to membrane, integral to plasma membrane, plasma membrane opioid receptor activity Human OPHN1 Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0051966=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0030036=GO_REF:0000019, GO:0007264=Reactome:REACT_11044, GO:0003779=GO_REF:0000019, GO:0048488=GO_REF:0000019, GO:0015629=GO_REF:0000019, GO:0005100=GO_REF:0000019, GO:0005829=Reactome:REACT_9982, GO:0007399=PMID:9582072, GO:0005622=GO_REF:0000002, GO:0006930=PMID:9582072, GO:0007165=PMID:9582072, GO:0005543=GO_REF:0000002, GO:0043197=GO_REF:0000039, GO:0035255=GO_REF:0000019, GO:0007411=PMID:9582072, GO:0030100=GO_REF:0000019, GO:0043195=GO_REF:0000019, GO:0005096=GO_REF:0000038} O60890 Oligophrenin-1 protein 20130301 {GO:0051056=TAS, GO:0051966=IEA, GO:0030054=IEA, GO:0030036=IEA, GO:0007264=TAS, GO:0003779=IEA, GO:0048488=IEA, GO:0015629=IEA, GO:0005100=IEA, GO:0005829=TAS, GO:0007399=TAS, GO:0005622=IEA, GO:0006930=TAS, GO:0007165=TAS, GO:0005543=IEA, GO:0043197=IEA, GO:0035255=IEA, GO:0007411=TAS, GO:0030100=IEA, GO:0043195=IEA, GO:0005096=IEA} actin cytoskeleton organization, axon guidance, nervous system development, regulation of endocytosis, regulation of small GTPase mediated signal transduction, regulation of synaptic transmission, glutamatergic, signal transduction, small GTPase mediated signal transduction, substrate-dependent cell migration, cell extension, synaptic vesicle endocytosis actin cytoskeleton, cell junction, cytosol, dendritic spine, intracellular, terminal bouton GTPase activator activity, Rho GTPase activator activity, actin binding, ionotropic glutamate receptor binding, phospholipid binding Human OPLAH Reactome UniProtKB {GO:0006805=Reactome:REACT_13433, GO:0017168=Reactome:REACT_75909, GO:0006750=Reactome:REACT_6960, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_75909} O14841 5-oxoprolinase protein 20110408 {GO:0006805=TAS, GO:0017168=TAS, GO:0006750=TAS, GO:0044281=TAS, GO:0005524=IEA, GO:0005829=TAS} glutathione biosynthetic process, small molecule metabolic process, xenobiotic metabolic process cytosol 5-oxoprolinase (ATP-hydrolyzing) activity, ATP binding Human OPN1LW Reactome UniProtKB {GO:0007165=PMID:2937147, GO:0018298=GO_REF:0000037, GO:0009881=GO_REF:0000037, GO:0007603=Reactome:REACT_160125, GO:0042622=Reactome:REACT_18363, GO:0005887=PMID:9860863, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000038, GO:0007602=GO_REF:0000002, GO:0001523=Reactome:REACT_160083, GO:0007601=GO_REF:0000037} P04000 Long-wave-sensitive opsin 1 protein 20121116 {GO:0007165=TAS, GO:0018298=IEA, GO:0009881=IEA, GO:0007603=TAS, GO:0042622=TAS, GO:0005887=TAS, GO:0004930=IEA, GO:0016021=IEA, GO:0007602=IEA, GO:0001523=TAS, GO:0007601=IEA} phototransduction, phototransduction, visible light, protein-chromophore linkage, retinoid metabolic process, signal transduction, visual perception integral to membrane, integral to plasma membrane, photoreceptor outer segment membrane G-protein coupled receptor activity, photoreceptor activity Human OPN1MW Reactome UniProtKB {GO:0018298=GO_REF:0000037, GO:0009881=GO_REF:0000037, GO:0007603=Reactome:REACT_160125, GO:0007186=PMID:2937147, GO:0005886=PMID:20579627, GO:0042622=Reactome:REACT_160262, GO:0005887=PMID:2937147, GO:0004930=GO_REF:0000037, GO:0001523=Reactome:REACT_160083, GO:0007601=GO_REF:0000037} P04001 Medium-wave-sensitive opsin 1 protein 20121116 {GO:0018298=IEA, GO:0009881=IEA, GO:0007603=TAS, GO:0007186=TAS, GO:0005886=IDA, GO:0042622=TAS, GO:0005887=TAS, GO:0004930=IEA, GO:0001523=TAS, GO:0007601=IEA} G-protein coupled receptor signaling pathway, phototransduction, visible light, protein-chromophore linkage, retinoid metabolic process, visual perception integral to plasma membrane, photoreceptor outer segment membrane, plasma membrane G-protein coupled receptor activity, photoreceptor activity Human OPN4 GOC UniProtKB {GO:0005502=PMID:15674244, GO:0009584=PMID:15674244, GO:0018298=GO_REF:0000037, GO:0009881=GO_REF:0000038, GO:0005886=Reactome:REACT_22436, GO:0004930=GO_REF:0000038, GO:0042752=GO_REF:0000024, GO:0048511=GO_REF:0000037, GO:0016021=PMID:10632589, GO:0007602=PMID:15674244, GO:0007601=GO_REF:0000002, GO:0008020=PMID:15674244} Q9UHM6 Melanopsin protein 20130413 {GO:0005502=IDA, GO:0009584=IDA, GO:0018298=IEA, GO:0009881=IEA, GO:0005886=TAS, GO:0004930=IEA, GO:0042752=ISS, GO:0048511=IEA, GO:0016021=TAS, GO:0007602=IDA, GO:0007601=IEA, GO:0008020=IDA} detection of visible light, phototransduction, protein-chromophore linkage, regulation of circadian rhythm, rhythmic process, visual perception integral to membrane, plasma membrane 11-cis retinal binding, G-protein coupled photoreceptor activity, G-protein coupled receptor activity, photoreceptor activity Human OPRD1 IntAct UniProtKB {GO:0005515=PMID:15086532, GO:0008344=GO_REF:0000019, GO:0005886=Reactome:REACT_22289, GO:0038046=PMID:9548483, GO:0007200=GO_REF:0000024, GO:0038003=PMID:9548483, GO:0007193=GO_REF:0000019, GO:0031982=GO_REF:0000019, GO:0006955=PMID:9548483, GO:0005737=GO_REF:0000019, GO:0032590=GO_REF:0000019, GO:0007186=PMID:16325578, GO:0071363=GO_REF:0000019, GO:0005887=PMID:7808419, GO:0007218=GO_REF:0000019, GO:0007187=PMID:7808419, GO:0045211=GO_REF:0000019, GO:0051924=GO_REF:0000019, GO:0043679=GO_REF:0000019, GO:0045121=GO_REF:0000019, GO:0051930=GO_REF:0000019, GO:0000060=PMID:16325578} P41143 Delta-type opioid receptor protein 20130415 {GO:0005515=IPI, GO:0008344=IEA, GO:0005886=TAS, GO:0038046=IMP, GO:0007200=ISS, GO:0038003=IMP, GO:0007193=IEA, GO:0031982=IEA, GO:0006955=TAS, GO:0005737=IEA, GO:0032590=IEA, GO:0007186=IDA, GO:0071363=IEA, GO:0005887=TAS, GO:0007218=IEA, GO:0007187=TAS, GO:0045211=IEA, GO:0051924=IEA, GO:0043679=IEA, GO:0045121=IEA, GO:0051930=IEA, GO:0000060=IDA} G-protein coupled receptor signaling pathway, G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, adult locomotory behavior, cellular response to growth factor stimulus, immune response, neuropeptide signaling pathway, opioid receptor signaling pathway, phospholipase C-activating G-protein coupled receptor signaling pathway, protein import into nucleus, translocation, regulation of calcium ion transport, regulation of sensory perception of pain axon terminus, cytoplasm, dendrite membrane, integral to plasma membrane, membrane raft, plasma membrane, postsynaptic membrane, vesicle enkephalin receptor activity, protein binding Human UniProtKB:Q5JY77 OPRK1 IntAct UniProtKB {GO:0005515=PMID:16431922, GO:0038048=PMID:8755601, GO:0005886=Reactome:REACT_22289, GO:0007200=GO_REF:0000024, GO:0007268=PMID:7624359, GO:0038003=PMID:8755601, GO:0007193=PMID:7624359, GO:0006955=PMID:8755601, GO:0051607=PMID:8755601, GO:0005887=PMID:7624359, GO:0007610=PMID:7624359, GO:0016021=GO_REF:0000002, GO:0007600=PMID:7624359} P41145 Kappa-type opioid receptor protein 20130415 {GO:0005515=IPI, GO:0038048=IDA, GO:0005886=TAS, GO:0007200=ISS, GO:0007268=TAS, GO:0038003=IDA, GO:0007193=TAS, GO:0006955=IDA, GO:0051607=IDA, GO:0005887=TAS, GO:0007610=TAS, GO:0016021=IEA, GO:0007600=TAS} adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, behavior, defense response to virus, immune response, opioid receptor signaling pathway, phospholipase C-activating G-protein coupled receptor signaling pathway, sensory perception, synaptic transmission integral to membrane, integral to plasma membrane, plasma membrane dynorphin receptor activity, protein binding Human UniProtKB:Q9H0R8 OPRL1 Reactome UniProtKB {GO:0005886=Reactome:REACT_22289, GO:0005887=PMID:8137918, GO:0004930=PMID:10571060, GO:0007193=PMID:10965058, GO:0007204=PMID:10571060, GO:0007600=PMID:7566152, GO:0001626=GO_REF:0000002} P41146 Nociceptin receptor protein 20080730 {GO:0005886=TAS, GO:0005887=TAS, GO:0004930=IGI, GO:0007193=TAS, GO:0007204=IGI, GO:0007600=TAS, GO:0001626=IEA} adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, elevation of cytosolic calcium ion concentration, sensory perception integral to plasma membrane, plasma membrane G-protein coupled receptor activity, nociceptin receptor activity Human OPRM1 IntAct UniProtKB {GO:0005515=PMID:19788913, GO:0008285=PMID:2159143, GO:0005886=Reactome:REACT_22289, GO:0005783=PMID:9242668, GO:2000310=GO_REF:0000024, GO:0007200=GO_REF:0000024, GO:0007194=GO_REF:0000024, GO:0007193=GO_REF:0000019, GO:0007191=GO_REF:0000019, GO:0001965=PMID:20214800, GO:0050769=GO_REF:0000024, GO:0007610=PMID:9689128, GO:0007626=GO_REF:0000019, GO:0061358=PMID:20214800, GO:0070374=GO_REF:0000024, GO:0038047=GO_REF:0000024, GO:0005794=PMID:9242668, GO:0005245=GO_REF:0000024, GO:0004930=GO_REF:0000024, GO:0004979=PMID:9689128, GO:0033554=PMID:21039637, GO:0019233=GO_REF:0000024, GO:0050795=PMID:21039637, GO:0048149=PMID:21039637, GO:0007187=PMID:7905839, GO:0005887=PMID:7905839, GO:0016021=GO_REF:0000002, GO:0007600=PMID:9689128} P35372 Mu-type opioid receptor protein 20130415 {GO:0005515=IPI, GO:0008285=TAS, GO:0005886=TAS, GO:0005783=TAS, GO:2000310=ISS, GO:0007200=ISS, GO:0007194=ISS, GO:0007193=IEA, GO:0007191=IEA, GO:0001965=IDA, GO:0050769=ISS, GO:0007610=NAS, GO:0007626=IEA, GO:0061358=IMP, GO:0070374=ISS, GO:0038047=ISS, GO:0005794=TAS, GO:0005245=ISS, GO:0004930=ISS, GO:0004979=IMP, GO:0033554=IMP, GO:0019233=ISS, GO:0050795=IMP, GO:0048149=IMP, GO:0007187=TAS, GO:0005887=TAS, GO:0016021=IEA, GO:0007600=NAS} G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, adenylate cyclase-activating dopamine receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, behavior, behavioral response to ethanol, cellular response to stress, locomotory behavior, negative regulation of Wnt protein secretion, negative regulation of adenylate cyclase activity, negative regulation of cell proliferation, phospholipase C-activating G-protein coupled receptor signaling pathway, positive regulation of ERK1 and ERK2 cascade, positive regulation of neurogenesis, regulation of N-methyl-D-aspartate selective glutamate receptor activity, regulation of behavior, sensory perception, sensory perception of pain Golgi apparatus, endoplasmic reticulum, integral to membrane, integral to plasma membrane, plasma membrane G-protein alpha-subunit binding, G-protein coupled receptor activity, beta-endorphin receptor activity, morphine receptor activity, protein binding, voltage-gated calcium channel activity Human UniProtKB:Q96S59 OPTC PINC UniProtKB {GO:0005578=GO_REF:0000039, GO:0005201=PMID:10636917} Q9UBM4 Opticin protein 20030904 {GO:0005578=IEA, GO:0005201=TAS} proteinaceous extracellular matrix extracellular matrix structural constituent Human OPTN HPA UniProtKB {GO:0005802=PMID:20174559, GO:0005515=PMID:21903422, GO:0008219=GO_REF:0000037, GO:0048471=GO_REF:0000039, GO:0005794=PMID:15837803, GO:0043001=PMID:15837803, GO:0090161=PMID:15837803, GO:0008022=PMID:15837803, GO:0005829=Reactome:REACT_160293, GO:0007165=PMID:9488477, GO:0005737=GO_REF:0000052, GO:0000139=Reactome:REACT_160293, GO:0000086=Reactome:REACT_2203, GO:0007030=PMID:15837803, GO:0005654=Reactome:REACT_160281, GO:0000278=Reactome:REACT_152, GO:0000042=PMID:15837803} Q96CV9 Optineurin protein 20080205 {GO:0005802=IDA, GO:0005515=IPI, GO:0008219=IEA, GO:0048471=IEA, GO:0005794=IDA, GO:0043001=IMP, GO:0090161=IDA, GO:0008022=IPI, GO:0005829=TAS, GO:0007165=TAS, GO:0005737=IDA, GO:0000139=TAS, GO:0000086=TAS, GO:0007030=IMP, GO:0005654=TAS, GO:0000278=TAS, GO:0000042=IMP} G2/M transition of mitotic cell cycle, Golgi organization, Golgi ribbon formation, Golgi to plasma membrane protein transport, cell death, mitotic cell cycle, protein targeting to Golgi, signal transduction Golgi apparatus, Golgi membrane, cytoplasm, cytosol, nucleoplasm, perinuclear region of cytoplasm, trans-Golgi network protein C-terminus binding, protein binding Human OR10J1 Reactome UniProtKB {GO:0007338=PMID:1370859, GO:0004984=GO_REF:0000002, GO:0005886=Reactome:REACT_15515, GO:0007186=PMID:1370859, GO:0005887=PMID:1370859, GO:0004930=GO_REF:0000037, GO:0007606=PMID:1370859} P30954 Olfactory receptor 10J1 protein 20081120 {GO:0007338=TAS, GO:0004984=IEA, GO:0005886=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0004930=IEA, GO:0007606=TAS} G-protein coupled receptor signaling pathway, sensory perception of chemical stimulus, single fertilization integral to plasma membrane, plasma membrane G-protein coupled receptor activity, olfactory receptor activity Human OR14I1 Reactome UniProtKB {GO:0004984=GO_REF:0000002, GO:0005886=Reactome:REACT_15515, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} A6ND48 Olfactory receptor 14I1 protein 20100521 {GO:0004984=IEA, GO:0005886=TAS, GO:0004930=IEA, GO:0016021=IEA} integral to membrane, plasma membrane G-protein coupled receptor activity, olfactory receptor activity Human OR1D2 GOC UniProtKB {GO:0007338=GO_REF:0000037, GO:0050911=PMID:12663925, GO:0007608=PMID:8097991, GO:0004984=PMID:12663925, GO:0005886=Reactome:REACT_15515, GO:0007186=PMID:16820410, GO:0006935=GO_REF:0000037, GO:0005887=PMID:8097991, GO:0004930=GO_REF:0000037, GO:0006928=PMID:1370859, GO:0000060=PMID:16820410} P34982 Olfactory receptor 1D2 protein 20130413 {GO:0007338=IEA, GO:0050911=IDA, GO:0007608=TAS, GO:0004984=IDA, GO:0005886=TAS, GO:0007186=IDA, GO:0006935=IEA, GO:0005887=TAS, GO:0004930=IEA, GO:0006928=TAS, GO:0000060=IMP} G-protein coupled receptor signaling pathway, cellular component movement, chemotaxis, detection of chemical stimulus involved in sensory perception of smell, protein import into nucleus, translocation, sensory perception of smell, single fertilization integral to plasma membrane, plasma membrane G-protein coupled receptor activity, olfactory receptor activity Human OR1E2 Reactome UniProtKB {GO:0007165=PMID:8004088, GO:0004984=GO_REF:0000002, GO:0005886=Reactome:REACT_15515, GO:0005887=PMID:8004088, GO:0004930=GO_REF:0000037, GO:0007606=PMID:8004088, GO:0004872=PMID:8004088} P47887 Olfactory receptor 1E2 protein 20081120 {GO:0007165=TAS, GO:0004984=IEA, GO:0005886=TAS, GO:0005887=TAS, GO:0004930=IEA, GO:0007606=TAS, GO:0004872=TAS} sensory perception of chemical stimulus, signal transduction integral to plasma membrane, plasma membrane G-protein coupled receptor activity, olfactory receptor activity, receptor activity Human OR1G1 Reactome UniProtKB {GO:0007165=PMID:8004088, GO:0004984=GO_REF:0000002, GO:0005886=Reactome:REACT_15515, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} P47890 Olfactory receptor 1G1 protein 20081120 {GO:0007165=NAS, GO:0004984=IEA, GO:0005886=TAS, GO:0004930=IEA, GO:0016021=IEA} signal transduction integral to membrane, plasma membrane G-protein coupled receptor activity, olfactory receptor activity Human OR1M1 Reactome UniProtKB {GO:0004984=GO_REF:0000002, GO:0005886=Reactome:REACT_15515, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q8NGA1 Olfactory receptor 1M1 protein 20081120 {GO:0004984=IEA, GO:0005886=TAS, GO:0004930=IEA, GO:0016021=IEA} integral to membrane, plasma membrane G-protein coupled receptor activity, olfactory receptor activity Human OR2AG1 Reactome UniProtKB {GO:0004984=GO_REF:0000002, GO:0005886=Reactome:REACT_15515, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q9H205 Olfactory receptor 2AG1 protein 20081120 {GO:0004984=IEA, GO:0005886=TAS, GO:0004930=IEA, GO:0016021=IEA} integral to membrane, plasma membrane G-protein coupled receptor activity, olfactory receptor activity Human OR2H1 Reactome UniProtKB {GO:0004984=GO_REF:0000002, GO:0005886=Reactome:REACT_15515, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q9GZK4 Olfactory receptor 2H1 protein 20081120 {GO:0004984=IEA, GO:0005886=TAS, GO:0004930=IEA, GO:0016021=IEA} integral to membrane, plasma membrane G-protein coupled receptor activity, olfactory receptor activity Human OR2L13 Reactome UniProtKB {GO:0005515=PMID:19945174, GO:0008150=GO_REF:0000015, GO:0004984=GO_REF:0000002, GO:0005886=Reactome:REACT_15515, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q8N349 Olfactory receptor 2L13 protein 20081120 {GO:0005515=IPI, GO:0008150=ND, GO:0004984=IEA, GO:0005886=TAS, GO:0004930=IEA, GO:0016021=IEA} biological_process integral to membrane, plasma membrane G-protein coupled receptor activity, olfactory receptor activity, protein binding Human OR2T35 Reactome UniProtKB {GO:0004984=GO_REF:0000002, GO:0005886=Reactome:REACT_15515, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q8NGX2 Olfactory receptor 2T35 protein 20081120 {GO:0004984=IEA, GO:0005886=TAS, GO:0004930=IEA, GO:0016021=IEA} integral to membrane, plasma membrane G-protein coupled receptor activity, olfactory receptor activity Human OR2T6 Reactome UniProtKB {GO:0004984=GO_REF:0000002, GO:0005886=Reactome:REACT_15515, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q8NHC8 Olfactory receptor 2T6 protein 20081120 {GO:0004984=IEA, GO:0005886=TAS, GO:0004930=IEA, GO:0016021=IEA} integral to membrane, plasma membrane G-protein coupled receptor activity, olfactory receptor activity Human OR2W1 Reactome UniProtKB {GO:0004984=GO_REF:0000002, GO:0005886=Reactome:REACT_15515, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q9Y3N9 Olfactory receptor 2W1 protein 20081120 {GO:0004984=IEA, GO:0005886=TAS, GO:0004930=IEA, GO:0016021=IEA} integral to membrane, plasma membrane G-protein coupled receptor activity, olfactory receptor activity Human OR3A1 GOC UniProtKB {GO:0050911=PMID:8647456, GO:0007165=PMID:8921386, GO:0004984=GO_REF:0000002, GO:0005886=Reactome:REACT_15515, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} P47881 Olfactory receptor 3A1 protein 20130413 {GO:0050911=TAS, GO:0007165=NAS, GO:0004984=IEA, GO:0005886=TAS, GO:0004930=IEA, GO:0016021=IEA} detection of chemical stimulus involved in sensory perception of smell, signal transduction integral to membrane, plasma membrane G-protein coupled receptor activity, olfactory receptor activity Human OR3A2 Reactome UniProtKB {GO:0007165=PMID:8921386, GO:0004984=GO_REF:0000002, GO:0005886=Reactome:REACT_15515, GO:0005887=PMID:8921386, GO:0004930=GO_REF:0000037, GO:0007606=PMID:8921386, GO:0004872=PMID:8921386} P47893 Olfactory receptor 3A2 protein 20081120 {GO:0007165=TAS, GO:0004984=IEA, GO:0005886=TAS, GO:0005887=TAS, GO:0004930=IEA, GO:0007606=TAS, GO:0004872=TAS} sensory perception of chemical stimulus, signal transduction integral to plasma membrane, plasma membrane G-protein coupled receptor activity, olfactory receptor activity, receptor activity Human OR4C12 Reactome UniProtKB {GO:0004984=GO_REF:0000002, GO:0005886=Reactome:REACT_15515, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q96R67 Olfactory receptor 4C12 protein 20081120 {GO:0004984=IEA, GO:0005886=TAS, GO:0004930=IEA, GO:0016021=IEA} integral to membrane, plasma membrane G-protein coupled receptor activity, olfactory receptor activity Human OR4D6 Reactome UniProtKB {GO:0004984=GO_REF:0000002, GO:0005886=Reactome:REACT_15515, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q8NGJ1 Olfactory receptor 4D6 protein 20081120 {GO:0004984=IEA, GO:0005886=TAS, GO:0004930=IEA, GO:0016021=IEA} integral to membrane, plasma membrane G-protein coupled receptor activity, olfactory receptor activity Human OR4F6 Reactome UniProtKB {GO:0004984=GO_REF:0000002, GO:0005886=Reactome:REACT_15515, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q8NGB9 Olfactory receptor 4F6 protein 20081120 {GO:0004984=IEA, GO:0005886=TAS, GO:0004930=IEA, GO:0016021=IEA} integral to membrane, plasma membrane G-protein coupled receptor activity, olfactory receptor activity Human OR4S2 Reactome UniProtKB {GO:0004984=GO_REF:0000002, GO:0005886=Reactome:REACT_15515, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q8NH73 Olfactory receptor 4S2 protein 20081120 {GO:0004984=IEA, GO:0005886=TAS, GO:0004930=IEA, GO:0016021=IEA} integral to membrane, plasma membrane G-protein coupled receptor activity, olfactory receptor activity Human OR51G1 Reactome UniProtKB {GO:0004984=GO_REF:0000002, GO:0005886=Reactome:REACT_15515, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q8NGK1 Olfactory receptor 51G1 protein 20081120 {GO:0004984=IEA, GO:0005886=TAS, GO:0004930=IEA, GO:0016021=IEA} integral to membrane, plasma membrane G-protein coupled receptor activity, olfactory receptor activity Human OR5H6 Reactome UniProtKB {GO:0004984=GO_REF:0000002, GO:0005886=Reactome:REACT_15515, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q8NGV6 Olfactory receptor 5H6 protein 20090601 {GO:0004984=IEA, GO:0005886=TAS, GO:0004930=IEA, GO:0016021=IEA} integral to membrane, plasma membrane G-protein coupled receptor activity, olfactory receptor activity Human OR6T1 Reactome UniProtKB {GO:0004984=GO_REF:0000002, GO:0005886=Reactome:REACT_15515, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q8NGN1 Olfactory receptor 6T1 protein 20091118 {GO:0004984=IEA, GO:0005886=TAS, GO:0004930=IEA, GO:0016021=IEA} integral to membrane, plasma membrane G-protein coupled receptor activity, olfactory receptor activity Human OR7A5 GOC UniProtKB {GO:0050911=PMID:9119360, GO:0007608=PMID:9119360, GO:0004984=PMID:9119360, GO:0005886=Reactome:REACT_15515, GO:0004930=GO_REF:0000037, GO:0016021=PMID:9119360} Q15622 Olfactory receptor 7A5 protein 20130413 {GO:0050911=NAS, GO:0007608=NAS, GO:0004984=NAS, GO:0005886=TAS, GO:0004930=IEA, GO:0016021=NAS} detection of chemical stimulus involved in sensory perception of smell, sensory perception of smell integral to membrane, plasma membrane G-protein coupled receptor activity, olfactory receptor activity Human OR7G3 Reactome UniProtKB {GO:0004984=GO_REF:0000002, GO:0005886=Reactome:REACT_15515, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q8NG95 Olfactory receptor 7G3 protein 20091118 {GO:0004984=IEA, GO:0005886=TAS, GO:0004930=IEA, GO:0016021=IEA} integral to membrane, plasma membrane G-protein coupled receptor activity, olfactory receptor activity Human OR8B2 UniProtKB UniProtKB {GO:0004984=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q96RD0 Olfactory receptor 8B2 protein 20130413 {GO:0004984=IEA, GO:0005886=IEA, GO:0004930=IEA, GO:0016021=IEA} integral to membrane, plasma membrane G-protein coupled receptor activity, olfactory receptor activity Human UniProtKB-SubCell:SL-0039 OR8D2 Reactome UniProtKB {GO:0004984=GO_REF:0000002, GO:0005886=Reactome:REACT_15515, GO:0004930=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q9GZM6 Olfactory receptor 8D2 protein 20091118 {GO:0004984=IEA, GO:0005886=TAS, GO:0004930=IEA, GO:0016021=IEA} integral to membrane, plasma membrane G-protein coupled receptor activity, olfactory receptor activity Human ORAI1 IntAct UniProtKB {GO:0005515=PMID:20418871, GO:0043234=GO_REF:0000019, GO:0002115=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0051928=PMID:16807233, GO:0005887=PMID:16645049, GO:0051924=PMID:16921383, GO:0015279=PMID:16645049} Q96D31 Calcium release-activated calcium channel protein 1 protein 20130415 {GO:0005515=IPI, GO:0043234=IEA, GO:0002115=IEA, GO:0007596=TAS, GO:0051928=IDA, GO:0005887=IDA, GO:0051924=IMP, GO:0015279=IDA} blood coagulation, positive regulation of calcium ion transport, regulation of calcium ion transport, store-operated calcium entry integral to plasma membrane, protein complex protein binding, store-operated calcium channel activity Human UniProtKB:Q9BSW2 ORAI2 UniProtKB UniProtKB {GO:0005515=PMID:20418871, GO:0016021=GO_REF:0000037} Q96SN7 Protein orai-2 protein 20100430 {GO:0005515=IPI, GO:0016021=IEA} integral to membrane protein binding Human UniProtKB:Q9BSW2 ORAI3 UniProtKB UniProtKB {GO:0005515=PMID:20418871, GO:0016021=GO_REF:0000037} Q9BRQ5 Protein orai-3 protein 20100430 {GO:0005515=IPI, GO:0016021=IEA} integral to membrane protein binding Human UniProtKB:Q9BSW2 ORAOV1 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q8WV07 Oral cancer-overexpressed protein 1 protein 20080901 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human ORC1 HPA UniProtKB {GO:0005515=PMID:17716973, GO:0017111=GO_REF:0000002, GO:0000808=PMID:17716973, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_480, GO:0006260=Reactome:REACT_6769, GO:0000084=Reactome:REACT_899, GO:0005737=GO_REF:0000052, GO:0000082=Reactome:REACT_1783, GO:0000083=Reactome:REACT_683, GO:0006270=PMID:7502077, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_22145, GO:0005664=PMID:21029866, GO:0000278=Reactome:REACT_152} Q13415 Origin recognition complex subunit 1 protein 20101115 {GO:0005515=IPI, GO:0017111=IEA, GO:0000808=IDA, GO:0005886=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0006260=TAS, GO:0000084=TAS, GO:0005737=IDA, GO:0000082=TAS, GO:0000083=TAS, GO:0006270=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0005664=IDA, GO:0000278=TAS} DNA replication, DNA replication initiation, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, cell cycle checkpoint, mitotic cell cycle, regulation of transcription involved in G1/S phase of mitotic cell cycle cytoplasm, cytosol, nuclear origin of replication recognition complex, nucleolus, nucleoplasm, nucleus, origin recognition complex, plasma membrane ATP binding, DNA binding, nucleoside-triphosphatase activity, protein binding Human ORC2 Reactome UniProtKB {GO:0000792=GO_REF:0000019, GO:0005515=PMID:20932478, GO:0000808=PMID:17716973, GO:0005634=PMID:8808289, GO:0003688=GO_REF:0000019, GO:0000122=PMID:8808289, GO:0006260=Reactome:REACT_6769, GO:0000084=Reactome:REACT_899, GO:0000082=Reactome:REACT_1783, GO:0006270=PMID:8808289, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_6750, GO:0005664=PMID:20932478, GO:0000278=Reactome:REACT_152, GO:0000939=GO_REF:0000019} Q13416 Origin recognition complex subunit 2 protein 20130213 {GO:0000792=IEA, GO:0005515=IPI, GO:0000808=IDA, GO:0005634=TAS, GO:0003688=IEA, GO:0000122=TAS, GO:0006260=TAS, GO:0000084=TAS, GO:0000082=TAS, GO:0006270=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0005664=IDA, GO:0000278=TAS, GO:0000939=IEA} DNA replication, DNA replication initiation, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, cell cycle checkpoint, mitotic cell cycle, negative regulation of transcription from RNA polymerase II promoter condensed chromosome inner kinetochore, heterochromatin, nuclear origin of replication recognition complex, nucleoplasm, nucleus, origin recognition complex DNA replication origin binding, protein binding Human ORC3 Reactome UniProtKB {GO:0000084=Reactome:REACT_899, GO:0006260=Reactome:REACT_6769, GO:0000082=Reactome:REACT_1783, GO:0000808=PMID:17716973, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_6750, GO:0003688=PMID:9829972, GO:0005664=PMID:20932478, GO:0000278=Reactome:REACT_152, GO:0003677=GO_REF:0000002} Q9UBD5 Origin recognition complex subunit 3 protein 20130213 {GO:0000084=TAS, GO:0006260=TAS, GO:0000082=TAS, GO:0000808=IDA, GO:0000075=TAS, GO:0005654=TAS, GO:0003688=TAS, GO:0005664=IDA, GO:0000278=TAS, GO:0003677=IEA} DNA replication, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, cell cycle checkpoint, mitotic cell cycle nuclear origin of replication recognition complex, nucleoplasm, origin recognition complex DNA binding, DNA replication origin binding Human ORC4 Reactome UniProtKB {GO:0017111=GO_REF:0000002, GO:0000808=PMID:17716973, GO:0005634=PMID:9353276, GO:0003688=PMID:9353276, GO:0005524=GO_REF:0000037, GO:0006260=Reactome:REACT_6769, GO:0000084=Reactome:REACT_899, GO:0000082=Reactome:REACT_1783, GO:0000166=PMID:9353276, GO:0006270=PMID:9353276, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_6750, GO:0005664=PMID:20932478, GO:0000278=Reactome:REACT_152} O43929 Origin recognition complex subunit 4 protein 20130213 {GO:0017111=IEA, GO:0000808=IDA, GO:0005634=IDA, GO:0003688=IMP, GO:0005524=IEA, GO:0006260=TAS, GO:0000084=TAS, GO:0000082=TAS, GO:0000166=IDA, GO:0006270=IMP, GO:0000075=TAS, GO:0005654=TAS, GO:0005664=IDA, GO:0000278=TAS} DNA replication, DNA replication initiation, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, cell cycle checkpoint, mitotic cell cycle nuclear origin of replication recognition complex, nucleoplasm, nucleus, origin recognition complex ATP binding, DNA replication origin binding, nucleoside-triphosphatase activity, nucleotide binding Human ORC5 HPA UniProtKB {GO:0005515=PMID:17716973, GO:0000808=PMID:17716973, GO:0005634=GO_REF:0000052, GO:0003688=PMID:9765232, GO:0005524=GO_REF:0000037, GO:0006260=Reactome:REACT_6769, GO:0000084=Reactome:REACT_899, GO:0003674=GO_REF:0000015, GO:0000082=Reactome:REACT_1783, GO:0005737=GO_REF:0000052, GO:0000166=PMID:9765232, GO:0006270=PMID:9765232, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_6750, GO:0005664=PMID:20932478, GO:0000278=Reactome:REACT_152} O43913 Origin recognition complex subunit 5 protein 20090616 {GO:0005515=IPI, GO:0000808=IDA, GO:0005634=IDA, GO:0003688=TAS, GO:0005524=IEA, GO:0006260=TAS, GO:0000084=TAS, GO:0003674=ND, GO:0000082=TAS, GO:0005737=IDA, GO:0000166=TAS, GO:0006270=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0005664=IDA, GO:0000278=TAS} DNA replication, DNA replication initiation, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, cell cycle checkpoint, mitotic cell cycle cytoplasm, nuclear origin of replication recognition complex, nucleoplasm, nucleus, origin recognition complex ATP binding, DNA replication origin binding, molecular_function, nucleotide binding, protein binding Human ORC6 Reactome UniProtKB {GO:0000084=Reactome:REACT_899, GO:0006260=Reactome:REACT_6769, GO:0006261=GO_REF:0000019, GO:0000082=Reactome:REACT_1783, GO:0000808=PMID:17716973, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_6750, GO:0005664=GO_REF:0000002, GO:0000278=Reactome:REACT_152, GO:0003677=GO_REF:0000037} Q9Y5N6 Origin recognition complex subunit 6 protein 20130213 {GO:0000084=TAS, GO:0006260=TAS, GO:0006261=IEA, GO:0000082=TAS, GO:0000808=IDA, GO:0000075=TAS, GO:0005654=TAS, GO:0005664=IEA, GO:0000278=TAS, GO:0003677=IEA} DNA replication, DNA-dependent DNA replication, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, cell cycle checkpoint, mitotic cell cycle nuclear origin of replication recognition complex, nucleoplasm, origin recognition complex DNA binding Human ORM1 IntAct UniProtKB {GO:0005515=PMID:16272158, GO:0006954=PMID:3360326, GO:0006810=GO_REF:0000037, GO:0002682=GO_REF:0000002, GO:0005576=PMID:14718574, GO:0006953=GO_REF:0000037, GO:0005615=GO_REF:0000002} P02763 Alpha-1-acid glycoprotein 1 protein 20130415 {GO:0005515=IPI, GO:0006954=TAS, GO:0006810=IEA, GO:0002682=IEA, GO:0005576=NAS, GO:0006953=IEA, GO:0005615=IEA} acute-phase response, inflammatory response, regulation of immune system process, transport extracellular region, extracellular space protein binding Human UniProtKB:P05121 ORM2 UniProtKB UniProtKB {GO:0006810=GO_REF:0000037, GO:0002682=GO_REF:0000002, GO:0006953=GO_REF:0000037, GO:0005615=GO_REF:0000002} P19652 Alpha-1-acid glycoprotein 2 protein 20130413 {GO:0006810=IEA, GO:0002682=IEA, GO:0006953=IEA, GO:0005615=IEA} acute-phase response, regulation of immune system process, transport extracellular space Human UniProtKB-KW:KW-0011 ORMDL1 UniProtKB UniProtKB {GO:0006672=PMID:20182505, GO:0005789=PMID:12093374, GO:0016021=GO_REF:0000037} Q9P0S3 ORM1-like protein 1 protein 20100305 {GO:0006672=IMP, GO:0005789=IDA, GO:0016021=IEA} ceramide metabolic process endoplasmic reticulum membrane, integral to membrane Human ORMDL2 UniProtKB UniProtKB {GO:0005783=PMID:12093374, GO:0006672=PMID:20182505, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q53FV1 ORM1-like protein 2 protein 20100305 {GO:0005783=IDA, GO:0006672=IMP, GO:0005789=IEA, GO:0016021=IEA} ceramide metabolic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane Human ORMDL3 UniProtKB UniProtKB {GO:0005515=PMID:20182505, GO:0005783=PMID:12093374, GO:0006672=PMID:20182505, GO:0035339=PMID:20182505, GO:0016021=GO_REF:0000037} Q8N138 ORM1-like protein 3 protein 20100305 {GO:0005515=IPI, GO:0005783=IDA, GO:0006672=IMP, GO:0035339=IDA, GO:0016021=IEA} ceramide metabolic process SPOTS complex, endoplasmic reticulum, integral to membrane protein binding Human OS9 IntAct UniProtKB {GO:0005515=PMID:15721254, GO:0000836=PMID:18502753, GO:0034976=PMID:19084021, GO:0001948=PMID:19346256, GO:0016567=PMID:19084021, GO:0042787=PMID:19084021, GO:0005788=PMID:18417469, GO:0006621=PMID:18417469, GO:0006605=GO_REF:0000019, GO:0030433=PMID:18417469, GO:0002020=GO_REF:0000019} Q13438 Protein OS-9 protein 20130415 {GO:0005515=IPI, GO:0000836=NAS, GO:0034976=IDA, GO:0001948=IDA, GO:0016567=IMP, GO:0042787=IMP, GO:0005788=IDA, GO:0006621=IDA, GO:0006605=IEA, GO:0030433=IMP, GO:0002020=IEA} ER-associated protein catabolic process, protein retention in ER lumen, protein targeting, protein ubiquitination, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, response to endoplasmic reticulum stress Hrd1p ubiquitin ligase complex, endoplasmic reticulum lumen glycoprotein binding, protease binding, protein binding Human UniProtKB:Q9GZT9 OSBP PINC UniProtKB {GO:0005543=GO_REF:0000002, GO:0008142=PMID:1970801, GO:0000139=GO_REF:0000039, GO:0006869=GO_REF:0000037} P22059 Oxysterol-binding protein 1 protein 20030904 {GO:0005543=IEA, GO:0008142=TAS, GO:0000139=IEA, GO:0006869=IEA} lipid transport Golgi membrane oxysterol binding, phospholipid binding Human OSBP2 UniProtKB UniProtKB {GO:0005543=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0006869=GO_REF:0000037} Q969R2 Oxysterol-binding protein 2 protein 20130413 {GO:0005543=IEA, GO:0016020=IEA, GO:0006869=IEA} lipid transport membrane phospholipid binding Human UniProtKB-SubCell:SL-0162 OSBPL10 UniProtKB UniProtKB {GO:0005543=GO_REF:0000002, GO:0006869=GO_REF:0000037} Q9BXB5 Oxysterol-binding protein-related protein 10 protein 20130413 {GO:0005543=IEA, GO:0006869=IEA} lipid transport phospholipid binding Human UniProtKB-KW:KW-0445 OSBPL11 BHF-UCL UniProtKB {GO:0005543=GO_REF:0000002, GO:0010890=PMID:23028956, GO:0006869=GO_REF:0000037, GO:0045444=PMID:23028956} Q9BXB4 Oxysterol-binding protein-related protein 11 protein 20130123 {GO:0005543=IEA, GO:0010890=IMP, GO:0006869=IEA, GO:0045444=IMP} fat cell differentiation, lipid transport, positive regulation of sequestering of triglyceride phospholipid binding Human OSBPL1A HPA UniProtKB {GO:0005515=PMID:16176980, GO:0005622=PMID:11279184, GO:0019886=Reactome:REACT_121399, GO:0005737=GO_REF:0000052, GO:0005543=PMID:11279184, GO:0005770=PMID:16176980, GO:0006869=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005765=Reactome:REACT_120995, GO:0016192=PMID:11279184, GO:0008203=PMID:10588946} Q9BXW6 Oxysterol-binding protein-related protein 1 protein 20111111 {GO:0005515=IPI, GO:0005622=IC, GO:0019886=TAS, GO:0005737=IDA, GO:0005543=NAS, GO:0005770=IDA, GO:0006869=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005765=TAS, GO:0016192=NAS, GO:0008203=NAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, cholesterol metabolic process, lipid transport, vesicle-mediated transport cytoplasm, intracellular, late endosome, lysosomal membrane, nucleolus, nucleus phospholipid binding, protein binding Human OSBPL2 UniProtKB UniProtKB {GO:0006869=GO_REF:0000037} Q9H1P3 Oxysterol-binding protein-related protein 2 protein 20130413 {GO:0006869=IEA} lipid transport Human UniProtKB-KW:KW-0445 OSBPL3 BHF-UCL UniProtKB {GO:0005515=PMID:22190034, GO:0031965=PMID:14593528, GO:0005543=GO_REF:0000002, GO:0005886=PMID:14593528, GO:0006869=GO_REF:0000037, GO:0097038=PMID:14593528, GO:0005829=PMID:14593528} Q9H4L5 Oxysterol-binding protein-related protein 3 protein 20130118 {GO:0005515=IPI, GO:0031965=IDA, GO:0005543=IEA, GO:0005886=IDA, GO:0006869=IEA, GO:0097038=IDA, GO:0005829=IDA} lipid transport cytosol, nuclear membrane, perinuclear endoplasmic reticulum, plasma membrane phospholipid binding, protein binding Human OSBPL5 UniProtKB UniProtKB {GO:0005543=GO_REF:0000002, GO:0008142=PMID:10588946, GO:0006869=GO_REF:0000038, GO:0005789=GO_REF:0000039, GO:0006893=PMID:10588946, GO:0030301=PMID:10588946, GO:0016021=GO_REF:0000037, GO:0008203=PMID:10588946, GO:0005829=PMID:10588946} Q9H0X9 Oxysterol-binding protein-related protein 5 protein 20021018 {GO:0005543=IEA, GO:0008142=NAS, GO:0006869=IEA, GO:0005789=IEA, GO:0006893=NAS, GO:0030301=NAS, GO:0016021=IEA, GO:0008203=NAS, GO:0005829=NAS} Golgi to plasma membrane transport, cholesterol metabolic process, cholesterol transport, lipid transport cytosol, endoplasmic reticulum membrane, integral to membrane oxysterol binding, phospholipid binding Human OSBPL6 BHF-UCL UniProtKB {GO:0005515=PMID:22190034, GO:0031965=PMID:14593528, GO:0005543=GO_REF:0000002, GO:0005886=PMID:14593528, GO:0006869=GO_REF:0000037, GO:0097038=PMID:14593528, GO:0005829=PMID:14593528} Q9BZF3 Oxysterol-binding protein-related protein 6 protein 20130118 {GO:0005515=IPI, GO:0031965=IDA, GO:0005543=IEA, GO:0005886=IDA, GO:0006869=IEA, GO:0097038=IDA, GO:0005829=IDA} lipid transport cytosol, nuclear membrane, perinuclear endoplasmic reticulum, plasma membrane phospholipid binding, protein binding Human OSBPL8 BHF-UCL UniProtKB {GO:0005543=GO_REF:0000002, GO:0010891=PMID:23028956, GO:0006869=GO_REF:0000037, GO:0045444=PMID:23028956} Q9BZF1 Oxysterol-binding protein-related protein 8 protein 20130123 {GO:0005543=IEA, GO:0010891=IDA, GO:0006869=IEA, GO:0045444=IDA} fat cell differentiation, lipid transport, negative regulation of sequestering of triglyceride phospholipid binding Human OSBPL9 UniProtKB UniProtKB {GO:0005543=GO_REF:0000002, GO:0006869=GO_REF:0000037} Q96SU4 Oxysterol-binding protein-related protein 9 protein 20130413 {GO:0005543=IEA, GO:0006869=IEA} lipid transport phospholipid binding Human UniProtKB-KW:KW-0445 OSCAR UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q8IYS5 Osteoclast-associated immunoglobulin-like receptor protein 20130413 {GO:0005886=IEA, GO:0005576=IEA, GO:0016021=IEA} extracellular region, integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 OSGEP UniProtKB UniProtKB {GO:0046872=GO_REF:0000037, GO:0008033=GO_REF:0000037} Q9NPF4 Probable tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP protein 20130413 {GO:0046872=IEA, GO:0008033=IEA} tRNA processing metal ion binding Human UniProtKB-KW:KW-0479 OSGIN1 UniProtKB UniProtKB {GO:0030308=PMID:11459809, GO:0007275=GO_REF:0000037, GO:0005575=GO_REF:0000015, GO:0008083=PMID:11459809, GO:0030154=GO_REF:0000037} Q9UJX0 Oxidative stress-induced growth inhibitor 1 protein 20061026 {GO:0030308=IDA, GO:0007275=IEA, GO:0005575=ND, GO:0008083=IDA, GO:0030154=IEA} cell differentiation, multicellular organismal development, negative regulation of cell growth cellular_component growth factor activity Human OSGIN2 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0007126=GO_REF:0000029, GO:0005575=GO_REF:0000015, GO:0007281=GO_REF:0000029} Q9Y236 Oxidative stress-induced growth inhibitor 2 protein 20061026 {GO:0003674=ND, GO:0007126=NAS, GO:0005575=ND, GO:0007281=NAS} germ cell development, meiosis cellular_component molecular_function Human OSM BHF-UCL UniProtKB {GO:0042506=GO_REF:0000019, GO:0008284=PMID:8999038, GO:0042503=GO_REF:0000019, GO:0008285=PMID:1717982, GO:0009408=GO_REF:0000019, GO:0008283=PMID:1542793, GO:0042508=GO_REF:0000019, GO:0050731=PMID:8999038, GO:0005615=GO_REF:0000037, GO:0046888=PMID:7867561, GO:0006955=GO_REF:0000002, GO:0033138=PMID:7508917, GO:0002675=PMID:8999038, GO:0045944=PMID:7508917, GO:0051781=GO_REF:0000037, GO:0005147=PMID:8999038, GO:0006915=GO_REF:0000019, GO:0005576=GO_REF:0000002, GO:0007275=PMID:1717982, GO:0005125=PMID:8999038, GO:0005900=PMID:8999038, GO:0007422=GO_REF:0000019, GO:0043410=PMID:7508917, GO:0045835=GO_REF:0000019, GO:0008083=PMID:8999038, GO:0048266=GO_REF:0000019, GO:0040008=GO_REF:0000037} P13725 Oncostatin-M protein 20081106 {GO:0042506=IEA, GO:0008284=IDA, GO:0042503=IEA, GO:0008285=TAS, GO:0009408=IEA, GO:0008283=TAS, GO:0042508=IEA, GO:0050731=IDA, GO:0005615=IEA, GO:0046888=IDA, GO:0006955=IEA, GO:0033138=IDA, GO:0002675=IC, GO:0045944=IDA, GO:0051781=IEA, GO:0005147=IPI, GO:0006915=IEA, GO:0005576=IEA, GO:0007275=TAS, GO:0005125=IDA, GO:0005900=IDA, GO:0007422=IEA, GO:0043410=IDA, GO:0045835=IEA, GO:0008083=IDA, GO:0048266=IEA, GO:0040008=IEA} apoptotic process, behavioral response to pain, cell proliferation, immune response, multicellular organismal development, negative regulation of cell proliferation, negative regulation of hormone secretion, negative regulation of meiosis, peripheral nervous system development, positive regulation of MAPK cascade, positive regulation of acute inflammatory response, positive regulation of cell division, positive regulation of cell proliferation, positive regulation of peptidyl-serine phosphorylation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of transcription from RNA polymerase II promoter, regulation of growth, response to heat, tyrosine phosphorylation of Stat1 protein, tyrosine phosphorylation of Stat3 protein, tyrosine phosphorylation of Stat5 protein extracellular region, extracellular space, oncostatin-M receptor complex cytokine activity, growth factor activity, oncostatin-M receptor binding Human UniProtKB:P40189 OSMR GOC UniProtKB {GO:0008284=PMID:8999038, GO:0019838=PMID:8999038, GO:0002675=PMID:8999038, GO:0008283=PMID:8999038, GO:0004924=PMID:8999038, GO:0005900=PMID:8999038, GO:0034097=PMID:8999038, GO:0007166=PMID:8999038, GO:0038165=PMID:8999038} Q99650 Oncostatin-M-specific receptor subunit beta protein 20130413 {GO:0008284=IGI, GO:0019838=IPI, GO:0002675=IC, GO:0008283=TAS, GO:0004924=IDA, GO:0005900=IDA, GO:0034097=IDA, GO:0007166=TAS, GO:0038165=IDA} cell proliferation, cell surface receptor signaling pathway, oncostatin-M-mediated signaling pathway, positive regulation of acute inflammatory response, positive regulation of cell proliferation, response to cytokine stimulus oncostatin-M receptor complex growth factor binding, oncostatin-M receptor activity Human OSR1 HPA UniProtKB {GO:0008406=GO_REF:0000019, GO:0001657=GO_REF:0000024, GO:0071300=GO_REF:0000019, GO:0001655=GO_REF:0000024, GO:0048793=PMID:21281489, GO:0072239=GO_REF:0000024, GO:0072234=GO_REF:0000024, GO:0072183=GO_REF:0000024, GO:0030154=GO_REF:0000024, GO:0072075=GO_REF:0000024, GO:0072180=GO_REF:0000024, GO:0007507=GO_REF:0000024, GO:0002062=GO_REF:0000024, GO:0072133=GO_REF:0000024, GO:0050679=GO_REF:0000024, GO:0030501=GO_REF:0000024, GO:0090094=GO_REF:0000024, GO:0072190=GO_REF:0000024, GO:0072208=GO_REF:0000024, GO:0072207=GO_REF:0000024, GO:0000122=GO_REF:0000024, GO:0072184=GO_REF:0000024, GO:0060272=GO_REF:0000024, GO:0048389=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0072143=GO_REF:0000024, GO:0042733=GO_REF:0000024, GO:0072111=GO_REF:0000024, GO:0005634=GO_REF:0000054, GO:0036023=GO_REF:0000024, GO:0030857=GO_REF:0000024, GO:0045944=GO_REF:0000024, GO:0042476=GO_REF:0000024, GO:0060021=GO_REF:0000024, GO:0042474=GO_REF:0000024, GO:0072259=GO_REF:0000024, GO:0043066=GO_REF:0000024, GO:0072498=GO_REF:0000024, GO:0001823=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:2000543=PMID:21281489, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0010628=GO_REF:0000024, GO:0048863=GO_REF:0000024, GO:0072268=GO_REF:0000024, GO:0035116=GO_REF:0000024, GO:0072166=GO_REF:0000024, GO:0072169=GO_REF:0000024, GO:0072168=GO_REF:0000024, GO:0035115=GO_REF:0000024, GO:0072162=GO_REF:0000024} Q8TAX0 Protein odd-skipped-related 1 protein 20090616 {GO:0008406=IEA, GO:0001657=ISS, GO:0071300=IEA, GO:0001655=ISS, GO:0048793=IMP, GO:0072239=ISS, GO:0072234=ISS, GO:0072183=ISS, GO:0030154=ISS, GO:0072075=ISS, GO:0072180=ISS, GO:0007507=ISS, GO:0002062=ISS, GO:0072133=ISS, GO:0050679=ISS, GO:0030501=ISS, GO:0090094=ISS, GO:0072190=ISS, GO:0072208=ISS, GO:0072207=ISS, GO:0000122=ISS, GO:0072184=ISS, GO:0060272=ISS, GO:0048389=IEA, GO:0008270=IEA, GO:0072143=ISS, GO:0042733=ISS, GO:0072111=ISS, GO:0005634=IDA, GO:0036023=ISS, GO:0030857=ISS, GO:0045944=ISS, GO:0042476=ISS, GO:0060021=ISS, GO:0042474=ISS, GO:0072259=ISS, GO:0043066=ISS, GO:0072498=ISS, GO:0001823=ISS, GO:0005730=IDA, GO:2000543=IMP, GO:0003676=IEA, GO:0006351=IEA, GO:0010628=ISS, GO:0048863=ISS, GO:0072268=ISS, GO:0035116=ISS, GO:0072166=ISS, GO:0072169=ISS, GO:0072168=ISS, GO:0035115=ISS, GO:0072162=ISS} cell differentiation, cell proliferation involved in kidney development, cellular response to retinoic acid, chondrocyte differentiation, embryonic digit morphogenesis, embryonic forelimb morphogenesis, embryonic hindlimb morphogenesis, embryonic skeletal joint development, embryonic skeletal joint morphogenesis, embryonic skeletal limb joint morphogenesis, gonad development, heart development, intermediate mesoderm development, mesangial cell development, mesonephric duct morphogenesis, mesonephros development, metanephric cap mesenchymal cell proliferation involved in metanephros development, metanephric epithelium development, metanephric glomerulus vasculature development, metanephric interstitial cell development, metanephric mesenchymal cell differentiation, metanephric mesenchyme development, metanephric mesenchyme morphogenesis, metanephric nephron tubule development, metanephric smooth muscle tissue development, middle ear morphogenesis, negative regulation of apoptotic process, negative regulation of epithelial cell differentiation, negative regulation of nephron tubule epithelial cell differentiation, negative regulation of transcription from RNA polymerase II promoter, odontogenesis, palate development, pattern specification involved in metanephros development, positive regulation of bone mineralization, positive regulation of epithelial cell proliferation, positive regulation of gastrulation, positive regulation of gene expression, positive regulation of transcription from RNA polymerase II promoter, posterior mesonephric tubule development, pronephros development, renal vesicle progenitor cell differentiation, specification of anterior mesonephric tubule identity, specification of posterior mesonephric tubule identity, stem cell differentiation, transcription, DNA-dependent, ureter urothelium development, ureteric bud development, urogenital system development nucleolus, nucleus nucleic acid binding, zinc ion binding Human OSR2 BHF-UCL UniProtKB {GO:0001656=GO_REF:0000024, GO:0008284=GO_REF:0000024, GO:0033687=GO_REF:0000024, GO:0048793=GO_REF:0000019, GO:0048704=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0009790=GO_REF:0000024, GO:0030154=GO_REF:0000024, GO:0036023=GO_REF:0000024, GO:0002062=GO_REF:0000024, GO:0045944=GO_REF:0000024, GO:0061029=GO_REF:0000024, GO:0042476=GO_REF:0000024, GO:0060021=GO_REF:0000024, GO:0042474=GO_REF:0000024, GO:0050679=GO_REF:0000024, GO:0030501=GO_REF:0000024, GO:0072498=GO_REF:0000024, GO:0001823=GO_REF:0000024, GO:2000543=GO_REF:0000019, GO:0000122=GO_REF:0000024, GO:0003676=GO_REF:0000002, GO:0010628=GO_REF:0000024, GO:0043565=GO_REF:0000024, GO:0060272=GO_REF:0000024, GO:0060349=GO_REF:0000024, GO:0035116=GO_REF:0000024, GO:0060322=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0035115=GO_REF:0000024, GO:0045893=GO_REF:0000024, GO:0042733=GO_REF:0000024} Q8N2R0 Protein odd-skipped-related 2 protein 20110429 {GO:0001656=ISS, GO:0008284=ISS, GO:0033687=ISS, GO:0048793=IEA, GO:0048704=ISS, GO:0005634=ISS, GO:0009790=ISS, GO:0030154=ISS, GO:0036023=ISS, GO:0002062=ISS, GO:0045944=ISS, GO:0061029=ISS, GO:0042476=ISS, GO:0060021=ISS, GO:0042474=ISS, GO:0050679=ISS, GO:0030501=ISS, GO:0072498=ISS, GO:0001823=ISS, GO:2000543=IEA, GO:0000122=ISS, GO:0003676=IEA, GO:0010628=ISS, GO:0043565=ISS, GO:0060272=ISS, GO:0060349=ISS, GO:0035116=ISS, GO:0060322=ISS, GO:0008270=IEA, GO:0035115=ISS, GO:0045893=ISS, GO:0042733=ISS} bone morphogenesis, cell differentiation, chondrocyte differentiation, embryo development, embryonic digit morphogenesis, embryonic forelimb morphogenesis, embryonic hindlimb morphogenesis, embryonic skeletal joint development, embryonic skeletal joint morphogenesis, embryonic skeletal limb joint morphogenesis, embryonic skeletal system morphogenesis, eyelid development in camera-type eye, head development, mesonephros development, metanephros development, middle ear morphogenesis, negative regulation of transcription from RNA polymerase II promoter, odontogenesis, osteoblast proliferation, palate development, positive regulation of bone mineralization, positive regulation of cell proliferation, positive regulation of epithelial cell proliferation, positive regulation of gastrulation, positive regulation of gene expression, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, pronephros development nucleus nucleic acid binding, sequence-specific DNA binding, zinc ion binding Human UniProtKB:Q91ZD1 OSTC HGNC UniProtKB {GO:0004579=PMID:15835887, GO:0016021=GO_REF:0000037, GO:0008250=PMID:15835887, GO:0018279=PMID:15835887} Q9NRP0 Oligosaccharyltransferase complex subunit OSTC protein 20090803 {GO:0004579=IC, GO:0016021=IEA, GO:0008250=IDA, GO:0018279=IC} protein N-linked glycosylation via asparagine integral to membrane, oligosaccharyltransferase complex dolichyl-diphosphooligosaccharide-protein glycotransferase activity Human GO:0008250 OSTF1 PINC UniProtKB {GO:0005622=PMID:10092216, GO:0007165=PMID:10092216, GO:0005737=GO_REF:0000039, GO:0017124=GO_REF:0000019, GO:0001503=PMID:10092216} Q92882 Osteoclast-stimulating factor 1 protein 20030904 {GO:0005622=TAS, GO:0007165=TAS, GO:0005737=IEA, GO:0017124=IEA, GO:0001503=TAS} ossification, signal transduction cytoplasm, intracellular SH3 domain binding Human OSTM1 Reactome UniProtKB {GO:0034220=Reactome:REACT_25300, GO:0030316=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0005765=Reactome:REACT_160230, GO:0055085=Reactome:REACT_15518, GO:0005829=GO_REF:0000019} Q86WC4 Osteopetrosis-associated transmembrane protein 1 protein 20121205 {GO:0034220=TAS, GO:0030316=IEA, GO:0016021=IEA, GO:0005765=TAS, GO:0055085=TAS, GO:0005829=IEA} ion transmembrane transport, osteoclast differentiation, transmembrane transport cytosol, integral to membrane, lysosomal membrane Human OTC HPA UniProtKB {GO:0019240=GO_REF:0000019, GO:0032868=GO_REF:0000019, GO:0055081=GO_REF:0000019, GO:0004585=Reactome:REACT_801, GO:0042493=GO_REF:0000019, GO:0009348=GO_REF:0000029, GO:0005743=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0010043=GO_REF:0000019, GO:0070781=GO_REF:0000019, GO:0005739=GO_REF:0000052, GO:0001889=GO_REF:0000019, GO:0034641=Reactome:REACT_13, GO:0070207=GO_REF:0000019, GO:0005543=GO_REF:0000019, GO:0005759=Reactome:REACT_801, GO:0007494=GO_REF:0000019, GO:0042301=GO_REF:0000019, GO:0006526=GO_REF:0000029, GO:0000050=Reactome:REACT_847, GO:0016597=GO_REF:0000019} P00480 Ornithine carbamoyltransferase, mitochondrial protein 20101115 {GO:0019240=IEA, GO:0032868=IEA, GO:0055081=IEA, GO:0004585=EXP, GO:0042493=IEA, GO:0009348=NAS, GO:0005743=IEA, GO:0044281=TAS, GO:0010043=IEA, GO:0070781=IEA, GO:0005739=IDA, GO:0001889=IEA, GO:0034641=TAS, GO:0070207=IEA, GO:0005543=IEA, GO:0005759=TAS, GO:0007494=IEA, GO:0042301=IEA, GO:0006526=NAS, GO:0000050=TAS, GO:0016597=IEA} anion homeostasis, arginine biosynthetic process, cellular nitrogen compound metabolic process, citrulline biosynthetic process, liver development, midgut development, protein homotrimerization, response to biotin, response to drug, response to insulin stimulus, response to zinc ion, small molecule metabolic process, urea cycle mitochondrial inner membrane, mitochondrial matrix, mitochondrion, ornithine carbamoyltransferase complex amino acid binding, ornithine carbamoyltransferase activity, phosphate ion binding, phospholipid binding Human OTOF PINC UniProtKB {GO:0003674=GO_REF:0000015, GO:0016323=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0006944=PMID:10192385, GO:0007605=GO_REF:0000037, GO:0005509=GO_REF:0000024, GO:0005789=GO_REF:0000039, GO:0030672=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0016079=GO_REF:0000024, GO:0005829=PMID:10192385} Q9HC10 Otoferlin protein 20050308 {GO:0003674=ND, GO:0016323=IEA, GO:0030054=IEA, GO:0006944=TAS, GO:0007605=IEA, GO:0005509=ISS, GO:0005789=IEA, GO:0030672=ISS, GO:0016021=IEA, GO:0016079=ISS, GO:0005829=TAS} cellular membrane fusion, sensory perception of sound, synaptic vesicle exocytosis basolateral plasma membrane, cell junction, cytosol, endoplasmic reticulum membrane, integral to membrane, synaptic vesicle membrane calcium ion binding, molecular_function Human OTOG UniProtKB UniProtKB {GO:0008344=GO_REF:0000019, GO:0016324=GO_REF:0000039, GO:0005198=GO_REF:0000019, GO:0007605=GO_REF:0000019, GO:0046556=GO_REF:0000002, GO:0046373=GO_REF:0000002, GO:0005578=GO_REF:0000019, GO:0005576=GO_REF:0000038, GO:0005615=GO_REF:0000039, GO:0005829=GO_REF:0000019} Q6ZRI0 Otogelin protein 20130413 {GO:0008344=IEA, GO:0016324=IEA, GO:0005198=IEA, GO:0007605=IEA, GO:0046556=IEA, GO:0046373=IEA, GO:0005578=IEA, GO:0005576=IEA, GO:0005615=IEA, GO:0005829=IEA} L-arabinose metabolic process, adult locomotory behavior, sensory perception of sound apical plasma membrane, cytosol, extracellular region, extracellular space, proteinaceous extracellular matrix alpha-N-arabinofuranosidase activity, structural molecule activity Human UniProtKB-SubCell:SL-0015 OTUB1 IntAct UniProtKB {GO:2000780=PMID:20725033, GO:0071108=PMID:19211026, GO:0005515=PMID:19615732, GO:0043130=PMID:19211026, GO:0004843=PMID:19211026, GO:0006974=PMID:20725033, GO:0019784=PMID:18954305, GO:0005737=GO_REF:0000039, GO:0006281=GO_REF:0000037, GO:1901315=PMID:20725033, GO:0006508=GO_REF:0000037, GO:0008242=GO_REF:0000002, GO:0019538=GO_REF:0000002, GO:0031625=PMID:20725033} Q96FW1 Ubiquitin thioesterase OTUB1 protein 20130415 {GO:2000780=IMP, GO:0071108=IDA, GO:0005515=IPI, GO:0043130=IDA, GO:0004843=IDA, GO:0006974=IDA, GO:0019784=IDA, GO:0005737=IEA, GO:0006281=IEA, GO:1901315=IDA, GO:0006508=IEA, GO:0008242=IEA, GO:0019538=IEA, GO:0031625=IPI} DNA repair, negative regulation of double-strand break repair, negative regulation of histone H2A K63-linked ubiquitination, protein K48-linked deubiquitination, protein metabolic process, proteolysis, response to DNA damage stimulus cytoplasm NEDD8-specific protease activity, omega peptidase activity, protein binding, ubiquitin binding, ubiquitin protein ligase binding, ubiquitin-specific protease activity Human UniProtKB:P62837 OTUB2 UniProtKB UniProtKB {GO:0071108=PMID:18954305, GO:0006520=PMID:12704427, GO:0016579=PMID:15258613, GO:0004843=PMID:18954305, GO:0070536=PMID:18954305, GO:0006508=GO_REF:0000037, GO:0005575=GO_REF:0000015, GO:0008242=GO_REF:0000002} Q96DC9 Ubiquitin thioesterase OTUB2 protein 20091117 {GO:0071108=IDA, GO:0006520=IDA, GO:0016579=IMP, GO:0004843=IDA, GO:0070536=IDA, GO:0006508=IEA, GO:0005575=ND, GO:0008242=IEA} cellular amino acid metabolic process, protein K48-linked deubiquitination, protein K63-linked deubiquitination, protein deubiquitination, proteolysis cellular_component omega peptidase activity, ubiquitin-specific protease activity Human OTUD1 null null {} null null null null {} null null null OTUD3 null null {} null null null null {} null null null OTUD4 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q01804 OTU domain-containing protein 4 protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human OTUD5 Reactome UniProtKB {GO:0071108=PMID:22245969, GO:0004843=PMID:22245969, GO:0070536=PMID:22245969, GO:0045087=Reactome:REACT_6802, GO:0032496=PMID:22245969, GO:0006508=GO_REF:0000037, GO:0032480=Reactome:REACT_25271, GO:0005829=Reactome:REACT_25055} Q96G74 OTU domain-containing protein 5 protein 20130301 {GO:0071108=IDA, GO:0004843=IDA, GO:0070536=IDA, GO:0045087=TAS, GO:0032496=IDA, GO:0006508=IEA, GO:0032480=TAS, GO:0005829=TAS} innate immune response, negative regulation of type I interferon production, protein K48-linked deubiquitination, protein K63-linked deubiquitination, proteolysis, response to lipopolysaccharide cytosol ubiquitin-specific protease activity Human OTUD6A null null {} null null null null {} null null null OTUD6B null null {} null null null null {} null null null OTUD7A UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0006508=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0008234=GO_REF:0000037, GO:0003677=GO_REF:0000002} Q8TE49 OTU domain-containing protein 7A protein 20130413 {GO:0005737=IEA, GO:0006508=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0008234=IEA, GO:0003677=IEA} proteolysis cytoplasm, nucleus DNA binding, cysteine-type peptidase activity, zinc ion binding Human UniProtKB-SubCell:SL-0086 OTUD7B HPA UniProtKB {GO:0071108=GO_REF:0000024, GO:0005515=PMID:21097510, GO:0016579=GO_REF:0000019, GO:0005634=PMID:11463333, GO:0003677=GO_REF:0000002, GO:0035871=PMID:20622874, GO:0005737=PMID:11463333, GO:0002385=GO_REF:0000024, GO:0070536=PMID:20622874, GO:0015630=GO_REF:0000052, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0004221=GO_REF:0000024, GO:0008234=GO_REF:0000024, GO:0043124=PMID:11463333} Q6GQQ9 OTU domain-containing protein 7B protein 20101115 {GO:0071108=ISS, GO:0005515=IPI, GO:0016579=IEA, GO:0005634=IDA, GO:0003677=IEA, GO:0035871=IDA, GO:0005737=IDA, GO:0002385=ISS, GO:0070536=IDA, GO:0015630=IDA, GO:0006508=IEA, GO:0008270=IEA, GO:0004221=ISS, GO:0008234=ISS, GO:0043124=IDA} mucosal immune response, negative regulation of I-kappaB kinase/NF-kappaB cascade, protein K11-linked deubiquitination, protein K48-linked deubiquitination, protein K63-linked deubiquitination, protein deubiquitination, proteolysis cytoplasm, microtubule cytoskeleton, nucleus DNA binding, cysteine-type peptidase activity, protein binding, ubiquitin thiolesterase activity, zinc ion binding Human OTX1 UniProtKB UniProtKB {GO:0022037=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000029, GO:0042472=GO_REF:0000019, GO:0006357=GO_REF:0000019, GO:0048852=GO_REF:0000019, GO:0007275=GO_REF:0000029, GO:0005634=GO_REF:0000029, GO:0030901=GO_REF:0000019, GO:0009952=GO_REF:0000019} P32242 Homeobox protein OTX1 protein 20021104 {GO:0022037=IEA, GO:0043565=IEA, GO:0006355=NAS, GO:0003700=NAS, GO:0042472=IEA, GO:0006357=IEA, GO:0048852=IEA, GO:0007275=NAS, GO:0005634=NAS, GO:0030901=IEA, GO:0009952=IEA} anterior/posterior pattern specification, diencephalon morphogenesis, inner ear morphogenesis, metencephalon development, midbrain development, multicellular organismal development, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human OTX2 UniProtKB UniProtKB {GO:0005515=PMID:20530484, GO:0003700=GO_REF:0000029, GO:0005634=GO_REF:0000039, GO:0009953=GO_REF:0000019, GO:0042706=GO_REF:0000019, GO:0030426=PMID:16267555, GO:0005737=GO_REF:0000019, GO:0032525=GO_REF:0000019, GO:0007411=PMID:16267555, GO:0045944=PMID:20530484, GO:0048852=GO_REF:0000019, GO:0040019=GO_REF:0000024, GO:0006355=GO_REF:0000029, GO:0042472=GO_REF:0000019, GO:0001708=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0090009=GO_REF:0000024, GO:2000543=GO_REF:0000024, GO:0003677=GO_REF:0000038, GO:0022037=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0043234=PMID:20530484, GO:0001077=PMID:20530484, GO:0006461=PMID:20530484, GO:0007492=GO_REF:0000019, GO:0040036=PMID:15705863, GO:0008589=PMID:15705863, GO:0008190=PMID:15705863, GO:0030901=PMID:15705863, GO:0030900=PMID:15705863, GO:0045893=GO_REF:0000024} P32243 Homeobox protein OTX2 protein 20110628 {GO:0005515=IPI, GO:0003700=NAS, GO:0005634=IEA, GO:0009953=IEA, GO:0042706=IEA, GO:0030426=IDA, GO:0005737=IEA, GO:0032525=IEA, GO:0007411=IDA, GO:0045944=IDA, GO:0048852=IEA, GO:0040019=ISS, GO:0006355=NAS, GO:0042472=IEA, GO:0001708=IEA, GO:0046982=IEA, GO:0090009=ISS, GO:2000543=ISS, GO:0003677=IEA, GO:0022037=IEA, GO:0043565=IEA, GO:0043234=IDA, GO:0001077=IDA, GO:0006461=IDA, GO:0007492=IEA, GO:0040036=TAS, GO:0008589=TAS, GO:0008190=TAS, GO:0030901=TAS, GO:0030900=TAS, GO:0045893=ISS} axon guidance, cell fate specification, diencephalon morphogenesis, dorsal/ventral pattern formation, endoderm development, eye photoreceptor cell fate commitment, forebrain development, inner ear morphogenesis, metencephalon development, midbrain development, positive regulation of embryonic development, positive regulation of gastrulation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, primitive streak formation, protein complex assembly, regulation of fibroblast growth factor receptor signaling pathway, regulation of smoothened signaling pathway, regulation of transcription, DNA-dependent, somite rostral/caudal axis specification cytoplasm, growth cone, nucleus, protein complex DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, eukaryotic initiation factor 4E binding, protein binding, protein heterodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human OVCA2 UniProtKB UniProtKB {GO:0005737=PMID:16368187, GO:0016787=PMID:11979432, GO:0032526=PMID:11979432} Q8WZ82 Ovarian cancer-associated gene 2 protein protein 20081106 {GO:0005737=IDA, GO:0016787=NAS, GO:0032526=IDA} response to retinoic acid cytoplasm hydrolase activity Human OVGP1 PINC UniProtKB {GO:0030133=GO_REF:0000039, GO:0007338=GO_REF:0000037, GO:0006032=GO_REF:0000002, GO:0007565=PMID:9341614, GO:0005975=GO_REF:0000002, GO:0004568=GO_REF:0000002, GO:0004553=GO_REF:0000002} Q12889 Oviduct-specific glycoprotein protein 20030904 {GO:0030133=IEA, GO:0007338=IEA, GO:0006032=IEA, GO:0007565=TAS, GO:0005975=IEA, GO:0004568=IEA, GO:0004553=IEA} carbohydrate metabolic process, chitin catabolic process, female pregnancy, single fertilization transport vesicle chitinase activity, hydrolase activity, hydrolyzing O-glycosyl compounds Human OVOL1 GOC UniProtKB {GO:0001078=GO_REF:0000019, GO:0006366=GO_REF:0000033, GO:0000239=GO_REF:0000019, GO:0001822=GO_REF:0000019, GO:0000981=GO_REF:0000033, GO:0043588=GO_REF:0000019, GO:0007498=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0007283=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037} O14753 Putative transcription factor Ovo-like 1 protein 20130413 {GO:0001078=IEA, GO:0006366=IBA, GO:0000239=IEA, GO:0001822=IEA, GO:0000981=IBA, GO:0043588=IEA, GO:0007498=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0007283=IEA, GO:0003676=IEA, GO:0003677=IEA} kidney development, mesoderm development, pachytene, skin development, spermatogenesis, transcription from RNA polymerase II promoter nucleus DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, nucleic acid binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, zinc ion binding Human PANTHER:PTN000003381 OXA1L HPA UniProtKB {GO:0005515=PMID:20601428, GO:0031966=PMID:20601428, GO:0051262=PMID:20739282, GO:0051354=PMID:17936786, GO:0051205=GO_REF:0000002, GO:0005743=GO_REF:0000019, GO:0032780=PMID:17936786, GO:0042803=PMID:20739282, GO:0005739=GO_REF:0000052, GO:0009060=PMID:9247084, GO:0043234=PMID:17936786, GO:0032981=PMID:17936786, GO:0005746=PMID:9247084, GO:0033615=PMID:17936786, GO:0006461=PMID:9247084, GO:0097031=PMID:20601428, GO:0032592=PMID:17936786, GO:0097177=PMID:20739282, GO:0016021=GO_REF:0000038, GO:0055114=PMID:9247084} Q15070 Mitochondrial inner membrane protein OXA1L protein 20080205 {GO:0005515=IPI, GO:0031966=IDA, GO:0051262=IDA, GO:0051354=IMP, GO:0051205=IEA, GO:0005743=IEA, GO:0032780=IMP, GO:0042803=IDA, GO:0005739=IDA, GO:0009060=NAS, GO:0043234=IDA, GO:0032981=IMP, GO:0005746=NAS, GO:0033615=IMP, GO:0006461=NAS, GO:0097031=IMP, GO:0032592=IDA, GO:0097177=IDA, GO:0016021=IEA, GO:0055114=NAS} aerobic respiration, mitochondrial proton-transporting ATP synthase complex assembly, mitochondrial respiratory chain complex I assembly, mitochondrial respiratory chain complex I biogenesis, negative regulation of ATPase activity, negative regulation of oxidoreductase activity, oxidation-reduction process, protein complex assembly, protein insertion into membrane, protein tetramerization integral to membrane, integral to mitochondrial membrane, mitochondrial inner membrane, mitochondrial membrane, mitochondrial respiratory chain, mitochondrion, protein complex mitochondrial ribosome binding, protein binding, protein homodimerization activity Human OXCT1 HPA UniProtKB {GO:0014823=GO_REF:0000019, GO:0007584=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0042803=PMID:10964512, GO:0005739=GO_REF:0000052, GO:0007507=GO_REF:0000019, GO:0042594=GO_REF:0000019, GO:0046952=Reactome:REACT_59, GO:0007420=GO_REF:0000019, GO:0005759=Reactome:REACT_1796, GO:0046950=Reactome:REACT_1861, GO:0008410=GO_REF:0000002, GO:0071229=GO_REF:0000019, GO:0032024=GO_REF:0000019, GO:0008260=Reactome:REACT_1796, GO:0009725=GO_REF:0000019, GO:0071333=GO_REF:0000019, GO:0060612=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0042182=GO_REF:0000019} P55809 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial protein 20081203 {GO:0014823=IEA, GO:0007584=IEA, GO:0042493=IEA, GO:0045471=IEA, GO:0044281=TAS, GO:0042803=NAS, GO:0005739=IDA, GO:0007507=IEA, GO:0042594=IEA, GO:0046952=TAS, GO:0007420=IEA, GO:0005759=TAS, GO:0046950=TAS, GO:0008410=IEA, GO:0071229=IEA, GO:0032024=IEA, GO:0008260=TAS, GO:0009725=IEA, GO:0071333=IEA, GO:0060612=IEA, GO:0044255=TAS, GO:0042182=IEA} adipose tissue development, brain development, cellular ketone body metabolic process, cellular lipid metabolic process, cellular response to acid, cellular response to glucose stimulus, heart development, ketone body catabolic process, ketone catabolic process, positive regulation of insulin secretion, response to activity, response to drug, response to ethanol, response to hormone stimulus, response to nutrient, response to starvation, small molecule metabolic process mitochondrial matrix, mitochondrion 3-oxoacid CoA-transferase activity, CoA-transferase activity, protein homodimerization activity Human OXCT2 MGI UniProtKB {GO:0005739=PMID:11756565, GO:0031514=PMID:11756565, GO:0046952=GO_REF:0000002, GO:0008260=GO_REF:0000003} Q9BYC2 Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial protein 20030801 {GO:0005739=IDA, GO:0031514=IDA, GO:0046952=IEA, GO:0008260=IEA} ketone body catabolic process mitochondrion, motile cilium 3-oxoacid CoA-transferase activity Human OXR1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0003674=GO_REF:0000015, GO:0016998=GO_REF:0000002, GO:0005730=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0006979=PMID:11114193} Q8N573 Oxidation resistance protein 1 protein 20061106 {GO:0005739=IEA, GO:0003674=ND, GO:0016998=IEA, GO:0005730=IEA, GO:0005575=ND, GO:0006979=NAS} cell wall macromolecule catabolic process, response to oxidative stress cellular_component, mitochondrion, nucleolus molecular_function Human OXSM HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0006637=PMID:15668256, GO:0005737=GO_REF:0000052, GO:0051792=PMID:15668256, GO:0051790=PMID:15668256, GO:0004315=PMID:15668256, GO:0003824=GO_REF:0000002, GO:0016740=GO_REF:0000038} Q9NWU1 "3-oxoacyl-""acyl-carrier-protein"" synthase, mitochondrial" protein 20090616 {GO:0005739=IDA, GO:0006637=IDA, GO:0005737=IDA, GO:0051792=IDA, GO:0051790=IDA, GO:0004315=IDA, GO:0003824=IEA, GO:0016740=IEA} acyl-CoA metabolic process, medium-chain fatty acid biosynthetic process, short-chain fatty acid biosynthetic process cytoplasm, mitochondrion "3-oxoacyl-acyl-carrier-protein"" synthase activity, catalytic activity, transferase activity""" Human OXSR1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0000287=PMID:14707132, GO:0004672=GO_REF:0000002, GO:0004674=PMID:14707132, GO:0006468=PMID:14707132, GO:0006979=GO_REF:0000019, GO:0005524=PMID:14707132, GO:0007243=PMID:14707132} O95747 Serine/threonine-protein kinase OSR1 protein 20050721 {GO:0005737=IEA, GO:0000287=IDA, GO:0004672=IEA, GO:0004674=IDA, GO:0006468=IDA, GO:0006979=IEA, GO:0005524=IDA, GO:0007243=IDA} intracellular protein kinase cascade, protein phosphorylation, response to oxidative stress cytoplasm ATP binding, magnesium ion binding, protein kinase activity, protein serine/threonine kinase activity Human OXT Reactome UniProtKB {GO:0060406=GO_REF:0000019, GO:0042220=GO_REF:0000019, GO:0051591=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0007507=GO_REF:0000019, GO:0034695=GO_REF:0000019, GO:0070474=GO_REF:0000019, GO:0009744=GO_REF:0000019, GO:0051602=GO_REF:0000019, GO:0007613=GO_REF:0000019, GO:0032355=GO_REF:0000019, GO:0045925=GO_REF:0000019, GO:0005185=GO_REF:0000002, GO:0051965=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0042538=GO_REF:0000019, GO:0030431=GO_REF:0000019, GO:0010701=GO_REF:0000019, GO:0002125=GO_REF:0000019, GO:0002027=GO_REF:0000019, GO:0050806=GO_REF:0000019, GO:0035176=GO_REF:0000019, GO:0035815=GO_REF:0000019, GO:0032570=GO_REF:0000019, GO:0035811=GO_REF:0000019, GO:0060179=GO_REF:0000019, GO:0051930=GO_REF:0000019, GO:0045472=GO_REF:0000019, GO:0031855=GO_REF:0000019, GO:0043434=GO_REF:0000019, GO:0045776=GO_REF:0000019, GO:0045777=GO_REF:0000019, GO:0045778=GO_REF:0000019, GO:0007204=GO_REF:0000019, GO:0060450=GO_REF:0000019, GO:0043195=GO_REF:0000019, GO:0060455=GO_REF:0000019, GO:0007625=GO_REF:0000019, GO:0032526=GO_REF:0000019, GO:0030141=GO_REF:0000019, GO:0042711=GO_REF:0000019, GO:0014823=GO_REF:0000019, GO:0005576=Reactome:REACT_22436, GO:0042713=GO_REF:0000019, GO:0007165=PMID:10218979, GO:0001975=GO_REF:0000019, GO:0042756=GO_REF:0000019, GO:0042755=GO_REF:0000019, GO:0032308=GO_REF:0000019} P01178 Oxytocin-neurophysin 1 protein 20081212 {GO:0060406=IEA, GO:0042220=IEA, GO:0051591=IEA, GO:0005615=IEA, GO:0007507=IEA, GO:0034695=IEA, GO:0070474=IEA, GO:0009744=IEA, GO:0051602=IEA, GO:0007613=IEA, GO:0032355=IEA, GO:0045925=IEA, GO:0005185=IEA, GO:0051965=IEA, GO:0007565=IEA, GO:0051384=IEA, GO:0042538=IEA, GO:0030431=IEA, GO:0010701=IEA, GO:0002125=IEA, GO:0002027=IEA, GO:0050806=IEA, GO:0035176=IEA, GO:0035815=IEA, GO:0032570=IEA, GO:0035811=IEA, GO:0060179=IEA, GO:0051930=IEA, GO:0045472=IEA, GO:0031855=IEA, GO:0043434=IEA, GO:0045776=IEA, GO:0045777=IEA, GO:0045778=IEA, GO:0007204=IEA, GO:0060450=IEA, GO:0043195=IEA, GO:0060455=IEA, GO:0007625=IEA, GO:0032526=IEA, GO:0030141=IEA, GO:0042711=IEA, GO:0014823=IEA, GO:0005576=TAS, GO:0042713=IEA, GO:0007165=TAS, GO:0001975=IEA, GO:0042756=IEA, GO:0042755=IEA, GO:0032308=IEA} drinking behavior, eating behavior, elevation of cytosolic calcium ion concentration, female pregnancy, grooming behavior, heart development, hyperosmotic salinity response, male mating behavior, maternal aggressive behavior, maternal behavior, memory, negative regulation of blood pressure, negative regulation of gastric acid secretion, negative regulation of urine volume, positive regulation of blood pressure, positive regulation of female receptivity, positive regulation of hindgut contraction, positive regulation of norepinephrine secretion, positive regulation of ossification, positive regulation of penile erection, positive regulation of prostaglandin secretion, positive regulation of renal sodium excretion, positive regulation of synapse assembly, positive regulation of synaptic transmission, positive regulation of uterine smooth muscle contraction, regulation of heart rate, regulation of sensory perception of pain, response to activity, response to amphetamine, response to cAMP, response to cocaine, response to electrical stimulus, response to estradiol stimulus, response to ether, response to glucocorticoid stimulus, response to peptide hormone stimulus, response to progesterone stimulus, response to prostaglandin E stimulus, response to retinoic acid, response to sucrose stimulus, signal transduction, sleep, social behavior, sperm ejaculation extracellular region, extracellular space, secretory granule, terminal bouton neurohypophyseal hormone activity, oxytocin receptor binding Human OXTR Reactome UniProtKB {GO:0005886=Reactome:REACT_22436, GO:0060406=GO_REF:0000019, GO:0043434=GO_REF:0000019, GO:0060206=GO_REF:0000019, GO:0045777=GO_REF:0000019, GO:0042220=GO_REF:0000019, GO:0007204=GO_REF:0000019, GO:0021537=GO_REF:0000019, GO:0007507=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0006936=PMID:1313946, GO:0005913=GO_REF:0000019, GO:0001967=GO_REF:0000019, GO:0070474=GO_REF:0000019, GO:0004990=GO_REF:0000019, GO:0005000=GO_REF:0000002, GO:0060455=GO_REF:0000019, GO:0007613=GO_REF:0000019, GO:0070371=GO_REF:0000019, GO:0034097=GO_REF:0000019, GO:0032355=GO_REF:0000019, GO:0051965=GO_REF:0000019, GO:0042711=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0051968=GO_REF:0000019, GO:0034059=GO_REF:0000019, GO:0060137=GO_REF:0000019, GO:0048565=GO_REF:0000019, GO:0030431=GO_REF:0000019, GO:0010701=GO_REF:0000019, GO:0032230=GO_REF:0000019, GO:0042713=GO_REF:0000019, GO:0005902=GO_REF:0000019, GO:0001975=GO_REF:0000019, GO:0007595=PMID:1313946, GO:0005887=PMID:10858434, GO:0035176=GO_REF:0000019, GO:0032570=GO_REF:0000019, GO:0042755=GO_REF:0000019, GO:0016021=GO_REF:0000002, GO:0017046=GO_REF:0000019, GO:0007166=PMID:1313946} P30559 Oxytocin receptor protein 20081212 {GO:0005886=TAS, GO:0060406=IEA, GO:0043434=IEA, GO:0060206=IEA, GO:0045777=IEA, GO:0042220=IEA, GO:0007204=IEA, GO:0021537=IEA, GO:0007507=IEA, GO:0016324=IEA, GO:0006936=TAS, GO:0005913=IEA, GO:0001967=IEA, GO:0070474=IEA, GO:0004990=IEA, GO:0005000=IEA, GO:0060455=IEA, GO:0007613=IEA, GO:0070371=IEA, GO:0034097=IEA, GO:0032355=IEA, GO:0051965=IEA, GO:0042711=IEA, GO:0007565=IEA, GO:0042493=IEA, GO:0051968=IEA, GO:0034059=IEA, GO:0060137=IEA, GO:0048565=IEA, GO:0030431=IEA, GO:0010701=IEA, GO:0032230=IEA, GO:0042713=IEA, GO:0005902=IEA, GO:0001975=IEA, GO:0007595=TAS, GO:0005887=TAS, GO:0035176=IEA, GO:0032570=IEA, GO:0042755=IEA, GO:0016021=IEA, GO:0017046=IEA, GO:0007166=TAS} ERK1 and ERK2 cascade, cell surface receptor signaling pathway, digestive tract development, eating behavior, elevation of cytosolic calcium ion concentration, estrous cycle phase, female pregnancy, heart development, lactation, maternal behavior, maternal process involved in parturition, memory, muscle contraction, negative regulation of gastric acid secretion, positive regulation of blood pressure, positive regulation of norepinephrine secretion, positive regulation of penile erection, positive regulation of synapse assembly, positive regulation of synaptic transmission, GABAergic, positive regulation of synaptic transmission, glutamatergic, positive regulation of uterine smooth muscle contraction, response to amphetamine, response to anoxia, response to cocaine, response to cytokine stimulus, response to drug, response to estradiol stimulus, response to peptide hormone stimulus, response to progesterone stimulus, sleep, social behavior, sperm ejaculation, suckling behavior, telencephalon development apical plasma membrane, cell-cell adherens junction, integral to membrane, integral to plasma membrane, microvillus, plasma membrane oxytocin receptor activity, peptide hormone binding, vasopressin receptor activity Human P2RX1 GOC UniProtKB {GO:0043005=GO_REF:0000019, GO:0005886=Reactome:REACT_23915, GO:0002554=GO_REF:0000019, GO:0051291=GO_REF:0000019, GO:0019228=GO_REF:0000019, GO:0043270=GO_REF:0000019, GO:0008144=GO_REF:0000019, GO:0045211=GO_REF:0000019, GO:0042310=GO_REF:0000019, GO:0006810=PMID:9565569, GO:0051924=GO_REF:0000019, GO:0001614=PMID:8834001, GO:0033198=GO_REF:0000019, GO:0051260=GO_REF:0000019, GO:0046513=GO_REF:0000019, GO:0006812=GO_REF:0000033, GO:0006811=PMID:8834001, GO:0035590=PMID:8834001, GO:0005262=Reactome:REACT_500, GO:0005261=PMID:8834001, GO:0004931=GO_REF:0000033, GO:0006919=GO_REF:0000019, GO:0035249=GO_REF:0000019, GO:0030168=GO_REF:0000019, GO:0005524=GO_REF:0000019, GO:0007320=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0007165=PMID:9565569, GO:0031240=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:9565569, GO:0003056=GO_REF:0000019, GO:0070588=Reactome:REACT_500, GO:0008217=GO_REF:0000019, GO:0008270=GO_REF:0000019, GO:0045121=GO_REF:0000019, GO:0005216=GO_REF:0000002} P51575 P2X purinoceptor 1 protein 20130413 {GO:0043005=IEA, GO:0005886=TAS, GO:0002554=IEA, GO:0051291=IEA, GO:0019228=IEA, GO:0043270=IEA, GO:0008144=IEA, GO:0045211=IEA, GO:0042310=IEA, GO:0006810=TAS, GO:0051924=IEA, GO:0001614=IDA, GO:0033198=IEA, GO:0051260=IEA, GO:0046513=IEA, GO:0006812=IBA, GO:0006811=IDA, GO:0035590=IDA, GO:0005262=TAS, GO:0005261=IDA, GO:0004931=IBA, GO:0006919=IEA, GO:0035249=IEA, GO:0030168=IEA, GO:0005524=IEA, GO:0007320=IEA, GO:0043234=IEA, GO:0007165=TAS, GO:0031240=IEA, GO:0016020=IEA, GO:0007596=TAS, GO:0005887=TAS, GO:0003056=IEA, GO:0070588=TAS, GO:0008217=IEA, GO:0008270=IEA, GO:0045121=IEA, GO:0005216=IEA} activation of cysteine-type endopeptidase activity involved in apoptotic process, blood coagulation, calcium ion transmembrane transport, cation transport, ceramide biosynthetic process, insemination, ion transport, platelet activation, positive regulation of ion transport, protein heterooligomerization, protein homooligomerization, purinergic nucleotide receptor signaling pathway, regulation of action potential in neuron, regulation of blood pressure, regulation of calcium ion transport, regulation of vascular smooth muscle contraction, response to ATP, serotonin secretion by platelet, signal transduction, synaptic transmission, glutamatergic, transport, vasoconstriction external side of cell outer membrane, integral to plasma membrane, membrane, membrane raft, neuron projection, plasma membrane, postsynaptic membrane, protein complex ATP binding, calcium channel activity, cation channel activity, drug binding, extracellular ATP-gated cation channel activity, ion channel activity, purinergic nucleotide receptor activity, zinc ion binding Human P2RX2 GOC UniProtKB {GO:0005886=GO_REF:0000019, GO:0010524=PMID:17895406, GO:0046870=GO_REF:0000019, GO:0051291=GO_REF:0000019, GO:0019228=GO_REF:0000019, GO:0042802=PMID:15313628, GO:0050850=PMID:17895406, GO:0009743=GO_REF:0000019, GO:0050909=GO_REF:0000019, GO:0007528=GO_REF:0000019, GO:0008144=GO_REF:0000019, GO:0043195=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0001614=PMID:17895406, GO:0033198=GO_REF:0000019, GO:0051260=PMID:15313628, GO:0014832=GO_REF:0000019, GO:0006812=GO_REF:0000033, GO:0015276=PMID:9119082, GO:0016151=GO_REF:0000019, GO:0035590=PMID:17895406, GO:0001666=GO_REF:0000019, GO:0004931=PMID:17895406, GO:0005507=GO_REF:0000019, GO:0014069=GO_REF:0000019, GO:0007274=GO_REF:0000019, GO:0005524=PMID:17895406, GO:0030432=GO_REF:0000019, GO:0003029=GO_REF:0000019, GO:0045340=GO_REF:0000019, GO:0042734=GO_REF:0000019, GO:0016020=GO_REF:0000033, GO:0008270=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0035091=GO_REF:0000019, GO:0048266=GO_REF:0000019, GO:0005216=GO_REF:0000002, GO:0050897=GO_REF:0000019} Q9UBL9 P2X purinoceptor 2 protein 20130413 {GO:0005886=IEA, GO:0010524=NAS, GO:0046870=IEA, GO:0051291=IEA, GO:0019228=IEA, GO:0042802=IPI, GO:0050850=NAS, GO:0009743=IEA, GO:0050909=IEA, GO:0007528=IEA, GO:0008144=IEA, GO:0043195=IEA, GO:0043025=IEA, GO:0001614=NAS, GO:0033198=IEA, GO:0051260=IPI, GO:0014832=IEA, GO:0006812=IBA, GO:0015276=TAS, GO:0016151=IEA, GO:0035590=NAS, GO:0001666=IEA, GO:0004931=NAS, GO:0005507=IEA, GO:0014069=IEA, GO:0007274=IEA, GO:0005524=NAS, GO:0030432=IEA, GO:0003029=IEA, GO:0045340=IEA, GO:0042734=IEA, GO:0016020=IBA, GO:0008270=IEA, GO:0016021=IEA, GO:0035091=IEA, GO:0048266=IEA, GO:0005216=IEA, GO:0050897=IEA} behavioral response to pain, cation transport, detection of hypoxic conditions in blood by carotid body chemoreceptor signaling, neuromuscular junction development, neuromuscular synaptic transmission, peristalsis, positive regulation of calcium ion transport into cytosol, positive regulation of calcium-mediated signaling, protein heterooligomerization, protein homooligomerization, purinergic nucleotide receptor signaling pathway, regulation of action potential in neuron, response to ATP, response to carbohydrate stimulus, response to hypoxia, sensory perception of taste, urinary bladder smooth muscle contraction integral to membrane, membrane, neuronal cell body, plasma membrane, postsynaptic density, presynaptic membrane, terminal bouton ATP binding, cadmium ion binding, cobalt ion binding, copper ion binding, drug binding, extracellular ATP-gated cation channel activity, identical protein binding, ion channel activity, ligand-gated ion channel activity, mercury ion binding, nickel cation binding, phosphatidylinositol binding, purinergic nucleotide receptor activity, zinc ion binding Human P2RX3 GOC UniProtKB {GO:0009408=GO_REF:0000019, GO:0010524=PMID:17895406, GO:0009409=GO_REF:0000019, GO:0019228=GO_REF:0000019, GO:0050850=PMID:17895406, GO:0009743=GO_REF:0000019, GO:0043197=GO_REF:0000019, GO:0050909=GO_REF:0000019, GO:0048167=GO_REF:0000019, GO:0043195=GO_REF:0000019, GO:0006810=PMID:9221902, GO:0043025=GO_REF:0000019, GO:0001614=PMID:17895406, GO:0033198=GO_REF:0000019, GO:0014832=GO_REF:0000019, GO:0051260=GO_REF:0000019, GO:0006812=GO_REF:0000033, GO:0035590=PMID:17895406, GO:0005791=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0005794=GO_REF:0000019, GO:0004931=PMID:17895406, GO:0007274=GO_REF:0000019, GO:0030432=GO_REF:0000019, GO:0005524=PMID:17895406, GO:0007165=PMID:9221902, GO:0016020=GO_REF:0000033, GO:0005887=PMID:9221902, GO:0045121=GO_REF:0000019, GO:0048266=GO_REF:0000019} P56373 P2X purinoceptor 3 protein 20130413 {GO:0009408=IEA, GO:0010524=NAS, GO:0009409=IEA, GO:0019228=IEA, GO:0050850=NAS, GO:0009743=IEA, GO:0043197=IEA, GO:0050909=IEA, GO:0048167=IEA, GO:0043195=IEA, GO:0006810=TAS, GO:0043025=IEA, GO:0001614=NAS, GO:0033198=IEA, GO:0014832=IEA, GO:0051260=IEA, GO:0006812=IBA, GO:0035590=NAS, GO:0005791=IEA, GO:0001666=IEA, GO:0005794=IEA, GO:0004931=NAS, GO:0007274=IEA, GO:0030432=IEA, GO:0005524=NAS, GO:0007165=TAS, GO:0016020=IBA, GO:0005887=TAS, GO:0045121=IEA, GO:0048266=IEA} behavioral response to pain, cation transport, neuromuscular synaptic transmission, peristalsis, positive regulation of calcium ion transport into cytosol, positive regulation of calcium-mediated signaling, protein homooligomerization, purinergic nucleotide receptor signaling pathway, regulation of action potential in neuron, regulation of synaptic plasticity, response to ATP, response to carbohydrate stimulus, response to cold, response to heat, response to hypoxia, sensory perception of taste, signal transduction, transport, urinary bladder smooth muscle contraction Golgi apparatus, dendritic spine, integral to plasma membrane, membrane, membrane raft, neuronal cell body, rough endoplasmic reticulum, terminal bouton ATP binding, extracellular ATP-gated cation channel activity, purinergic nucleotide receptor activity Human P2RX4 GOC UniProtKB {GO:0048471=PMID:12088286, GO:0051899=PMID:9016352, GO:0030054=PMID:12088286, GO:0005886=PMID:17785580, GO:0051928=PMID:15130891, GO:0010524=PMID:10899068, GO:0034405=PMID:10969036, GO:0042803=PMID:17895406, GO:0019228=GO_REF:0000019, GO:0045429=PMID:10899068, GO:0050850=PMID:10899068, GO:0006809=GO_REF:0000019, GO:0010614=PMID:15130891, GO:0001894=PMID:17264311, GO:0042311=GO_REF:0000019, GO:0043195=GO_REF:0000019, GO:0008144=GO_REF:0000019, GO:0006810=PMID:9016352, GO:0043025=GO_REF:0000019, GO:0033198=PMID:9016352, GO:0001614=PMID:11606481, GO:0006816=GO_REF:0000019, GO:0051260=GO_REF:0000019, GO:0035590=PMID:9016352, GO:0045296=PMID:12088286, GO:0004931=PMID:9016352, GO:0005507=PMID:12819199, GO:0005102=PMID:17785580, GO:0060079=GO_REF:0000019, GO:0006950=PMID:12088286, GO:0014069=GO_REF:0000019, GO:0045177=GO_REF:0000019, GO:0042981=PMID:17264311, GO:0005524=PMID:11606481, GO:0019233=PMID:14978347, GO:0007165=PMID:9016352, GO:0016020=PMID:17785580, GO:0005887=PMID:11606481, GO:0002028=PMID:17785580, GO:0008217=PMID:11606481, GO:0055117=PMID:11606481, GO:0032308=PMID:10899068, GO:0042118=PMID:12088286, GO:0055119=PMID:11606481, GO:0008270=PMID:12819199, GO:0016021=GO_REF:0000038, GO:0005216=GO_REF:0000002} Q99571 P2X purinoceptor 4 protein 20130413 {GO:0048471=IDA, GO:0051899=IDA, GO:0030054=IDA, GO:0005886=ISS, GO:0051928=NAS, GO:0010524=IMP, GO:0034405=IDA, GO:0042803=NAS, GO:0019228=IEA, GO:0045429=NAS, GO:0050850=IMP, GO:0006809=IEA, GO:0010614=IMP, GO:0001894=NAS, GO:0042311=IEA, GO:0043195=IEA, GO:0008144=IEA, GO:0006810=IDA, GO:0043025=IEA, GO:0033198=IDA, GO:0001614=IMP, GO:0006816=IEA, GO:0051260=IEA, GO:0035590=IDA, GO:0045296=IPI, GO:0004931=IDA, GO:0005507=ISS, GO:0005102=ISS, GO:0060079=IEA, GO:0006950=TAS, GO:0014069=IEA, GO:0045177=IEA, GO:0042981=IDA, GO:0005524=IC, GO:0019233=ISS, GO:0007165=IDA, GO:0016020=IDA, GO:0005887=IC, GO:0002028=ISS, GO:0008217=IMP, GO:0055117=IMP, GO:0032308=NAS, GO:0042118=TAS, GO:0055119=IMP, GO:0008270=ISS, GO:0016021=IEA, GO:0005216=IEA} calcium ion transport, endothelial cell activation, membrane depolarization, negative regulation of cardiac muscle hypertrophy, nitric oxide biosynthetic process, positive regulation of calcium ion transport, positive regulation of calcium ion transport into cytosol, positive regulation of calcium-mediated signaling, positive regulation of nitric oxide biosynthetic process, positive regulation of prostaglandin secretion, protein homooligomerization, purinergic nucleotide receptor signaling pathway, regulation of action potential in neuron, regulation of apoptotic process, regulation of blood pressure, regulation of cardiac muscle contraction, regulation of excitatory postsynaptic membrane potential, regulation of sodium ion transport, relaxation of cardiac muscle, response to ATP, response to fluid shear stress, response to stress, sensory perception of pain, signal transduction, tissue homeostasis, transport, vasodilation apical part of cell, cell junction, integral to membrane, integral to plasma membrane, membrane, neuronal cell body, perinuclear region of cytoplasm, plasma membrane, postsynaptic density, terminal bouton ATP binding, cadherin binding, copper ion binding, drug binding, extracellular ATP-gated cation channel activity, ion channel activity, protein homodimerization activity, purinergic nucleotide receptor activity, receptor binding, zinc ion binding Human P2RX5 GOC UniProtKB {GO:0035590=PMID:17895406, GO:0004931=PMID:17895406, GO:0010524=PMID:17895406, GO:0005524=PMID:17895406, GO:0050850=PMID:17895406, GO:0007399=PMID:9414125, GO:0007165=PMID:9414125, GO:0016020=GO_REF:0000033, GO:0005887=PMID:9414125, GO:0006810=PMID:9414125, GO:0001614=PMID:17895406, GO:0016021=GO_REF:0000038, GO:0005216=PMID:9414125, GO:0006812=GO_REF:0000033, GO:0004888=PMID:9414125} Q93086 P2X purinoceptor 5 protein 20130413 {GO:0035590=NAS, GO:0004931=NAS, GO:0010524=NAS, GO:0005524=NAS, GO:0050850=NAS, GO:0007399=TAS, GO:0007165=TAS, GO:0016020=IBA, GO:0005887=TAS, GO:0006810=TAS, GO:0001614=NAS, GO:0016021=IEA, GO:0005216=TAS, GO:0006812=IBA, GO:0004888=TAS} cation transport, nervous system development, positive regulation of calcium ion transport into cytosol, positive regulation of calcium-mediated signaling, purinergic nucleotide receptor signaling pathway, signal transduction, transport integral to membrane, integral to plasma membrane, membrane ATP binding, extracellular ATP-gated cation channel activity, ion channel activity, purinergic nucleotide receptor activity, transmembrane signaling receptor activity Human P2RX6 InterPro UniProtKB {GO:0035590=PMID:12088286, GO:0030054=PMID:12088286, GO:0004931=PMID:12088286, GO:0014069=GO_REF:0000019, GO:0005524=GO_REF:0000002, GO:0051291=GO_REF:0000019, GO:0042802=PMID:15313628, GO:0007165=PMID:9242461, GO:0005737=PMID:12088286, GO:0006936=PMID:9242461, GO:0016020=GO_REF:0000002, GO:0005887=PMID:9242461, GO:0043025=GO_REF:0000019, GO:0006810=PMID:9242461, GO:0001614=GO_REF:0000002, GO:0051260=PMID:15313628, GO:0016021=GO_REF:0000038, GO:0005216=GO_REF:0000002, GO:0006812=GO_REF:0000033, GO:0015267=PMID:9242461, GO:0004888=PMID:9242461} Q6P1Z3 P2X purinoceptor 6 protein 20130413 {GO:0035590=NAS, GO:0030054=IDA, GO:0004931=NAS, GO:0014069=IEA, GO:0005524=IEA, GO:0051291=IEA, GO:0042802=IPI, GO:0007165=TAS, GO:0005737=IDA, GO:0006936=TAS, GO:0016020=IEA, GO:0005887=TAS, GO:0043025=IEA, GO:0006810=TAS, GO:0001614=IEA, GO:0051260=IPI, GO:0016021=IEA, GO:0005216=IEA, GO:0006812=IBA, GO:0015267=TAS, GO:0004888=TAS} cation transport, muscle contraction, protein heterooligomerization, protein homooligomerization, purinergic nucleotide receptor signaling pathway, signal transduction, transport cell junction, cytoplasm, integral to membrane, integral to plasma membrane, membrane, neuronal cell body, postsynaptic density ATP binding, channel activity, extracellular ATP-gated cation channel activity, identical protein binding, ion channel activity, purinergic nucleotide receptor activity, transmembrane signaling receptor activity Human InterPro:IPR001429|InterPro:IPR003049 P2RX7 GOC UniProtKB {GO:0032755=GO_REF:0000019, GO:0006649=GO_REF:0000019, GO:0043132=GO_REF:0000019, GO:0031594=GO_REF:0000019, GO:0050830=GO_REF:0000019, GO:0010524=PMID:9038151, GO:0034405=GO_REF:0000019, GO:0048705=GO_REF:0000019, GO:0006900=GO_REF:0000019, GO:0051259=GO_REF:0000019, GO:0010043=GO_REF:0000019, GO:0042803=PMID:17895406, GO:0019228=GO_REF:0000019, GO:0006884=GO_REF:0000019, GO:0016485=GO_REF:0000019, GO:0031668=GO_REF:0000019, GO:0051602=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0001614=PMID:9038151, GO:0033198=PMID:9038151, GO:0006509=GO_REF:0000019, GO:0043029=GO_REF:0000019, GO:0051209=GO_REF:0000019, GO:0000287=GO_REF:0000019, GO:0030501=GO_REF:0000024, GO:0004931=PMID:9038151, GO:0005507=GO_REF:0000019, GO:0032060=GO_REF:0000024, GO:0001845=GO_REF:0000019, GO:0016079=GO_REF:0000019, GO:0046931=PMID:9038151, GO:0051592=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0032059=GO_REF:0000024, GO:0005887=PMID:9038151, GO:0045087=Reactome:REACT_6802, GO:0051495=GO_REF:0000024, GO:0002028=PMID:17785580, GO:0032963=GO_REF:0000019, GO:0045121=GO_REF:0000019, GO:0008270=GO_REF:0000019, GO:0007005=GO_REF:0000019, GO:0051709=PMID:17785580, GO:0005216=GO_REF:0000002, GO:0009897=GO_REF:0000019, GO:0007009=GO_REF:0000019, GO:0051899=PMID:9038151, GO:0005886=PMID:17785580, GO:0014054=GO_REF:0000019, GO:0045332=GO_REF:0000019, GO:0035872=Reactome:REACT_75913, GO:0045779=GO_REF:0000024, GO:0005639=GO_REF:0000019, GO:0043409=GO_REF:0000024, GO:0014049=GO_REF:0000019, GO:0000187=GO_REF:0000019, GO:0005737=GO_REF:0000024, GO:0048873=GO_REF:0000019, GO:0006954=GO_REF:0000019, GO:0051901=GO_REF:0000019, GO:0050717=GO_REF:0000019, GO:0042098=GO_REF:0000019, GO:0050718=PMID:17036048, GO:0005911=GO_REF:0000019, GO:0043195=GO_REF:0000019, GO:0097110=GO_REF:0000019, GO:0019835=GO_REF:0000019, GO:0046513=GO_REF:0000019, GO:0035590=PMID:9038151, GO:0043065=GO_REF:0000019, GO:0044254=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0072593=GO_REF:0000019, GO:0005102=PMID:17785580, GO:0042981=GO_REF:0000024, GO:0005524=PMID:9038151, GO:0019233=GO_REF:0000024, GO:0009612=GO_REF:0000019, GO:0001530=GO_REF:0000024, GO:0000902=GO_REF:0000019, GO:0016020=PMID:17785580, GO:0045919=GO_REF:0000024, GO:0001916=GO_REF:0000019, GO:0032308=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0007166=GO_REF:0000024} Q99572 P2X purinoceptor 7 protein 20130413 {GO:0032755=IEA, GO:0006649=IEA, GO:0043132=IEA, GO:0031594=IEA, GO:0050830=IEA, GO:0010524=IDA, GO:0034405=IEA, GO:0048705=IEA, GO:0006900=IEA, GO:0051259=IEA, GO:0010043=IEA, GO:0042803=NAS, GO:0019228=IEA, GO:0006884=IEA, GO:0016485=IEA, GO:0031668=IEA, GO:0051602=IEA, GO:0043025=IEA, GO:0032496=IEA, GO:0001614=IDA, GO:0033198=IDA, GO:0006509=IEA, GO:0043029=IEA, GO:0051209=IEA, GO:0000287=IEA, GO:0030501=ISS, GO:0004931=IDA, GO:0005507=IEA, GO:0032060=ISS, GO:0001845=IEA, GO:0016079=IEA, GO:0046931=IDA, GO:0051592=IEA, GO:0043234=IEA, GO:0032059=ISS, GO:0005887=IC, GO:0045087=TAS, GO:0051495=ISS, GO:0002028=ISS, GO:0032963=IEA, GO:0045121=IEA, GO:0008270=IEA, GO:0007005=IEA, GO:0051709=NAS, GO:0005216=IEA, GO:0009897=IEA, GO:0007009=IEA, GO:0051899=IDA, GO:0005886=ISS, GO:0014054=IEA, GO:0045332=IEA, GO:0035872=TAS, GO:0045779=ISS, GO:0005639=IEA, GO:0043409=ISS, GO:0014049=IEA, GO:0000187=IEA, GO:0005737=ISS, GO:0048873=IEA, GO:0006954=IEA, GO:0051901=IEA, GO:0050717=IEA, GO:0042098=IEA, GO:0050718=IDA, GO:0005911=IEA, GO:0043195=IEA, GO:0097110=IEA, GO:0019835=IEA, GO:0046513=IEA, GO:0035590=IDA, GO:0043065=IEA, GO:0044254=IEA, GO:0042493=IEA, GO:0072593=IEA, GO:0005102=ISS, GO:0042981=ISS, GO:0005524=IC, GO:0019233=ISS, GO:0009612=IEA, GO:0001530=ISS, GO:0000902=IEA, GO:0016020=IDA, GO:0045919=ISS, GO:0001916=IEA, GO:0032308=IEA, GO:0016021=IEA, GO:0007166=ISS} NAD transport, T cell homeostasis, T cell proliferation, activation of MAPK activity, bleb assembly, cell morphogenesis, cell surface receptor signaling pathway, cell volume homeostasis, cellular response to extracellular stimulus, ceramide biosynthetic process, collagen metabolic process, cytolysis, defense response to Gram-positive bacterium, homeostasis of number of cells within a tissue, inflammatory response, innate immune response, membrane budding, membrane depolarization, membrane protein ectodomain proteolysis, mitochondrion organization, multicellular organismal protein catabolic process, negative regulation of MAPK cascade, negative regulation of bone resorption, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, phagolysosome assembly, phospholipid transfer to membrane, phospholipid translocation, plasma membrane organization, pore complex assembly, positive regulation of T cell mediated cytotoxicity, positive regulation of apoptotic process, positive regulation of bone mineralization, positive regulation of calcium ion transport into cytosol, positive regulation of cytolysis, positive regulation of cytoskeleton organization, positive regulation of gamma-aminobutyric acid secretion, positive regulation of glutamate secretion, positive regulation of interleukin-1 alpha secretion, positive regulation of interleukin-1 beta secretion, positive regulation of interleukin-6 production, positive regulation of mitochondrial depolarization, positive regulation of prostaglandin secretion, protein oligomerization, protein processing, purinergic nucleotide receptor signaling pathway, reactive oxygen species metabolic process, regulation of action potential in neuron, regulation of apoptotic process, regulation of killing of cells of other organism, regulation of sodium ion transport, release of sequestered calcium ion into cytosol, response to ATP, response to calcium ion, response to drug, response to electrical stimulus, response to fluid shear stress, response to lipopolysaccharide, response to mechanical stimulus, response to zinc ion, sensory perception of pain, skeletal system morphogenesis, synaptic vesicle exocytosis bleb, cell-cell junction, cytoplasm, external side of plasma membrane, integral to membrane, integral to nuclear inner membrane, integral to plasma membrane, membrane, membrane raft, neuromuscular junction, neuronal cell body, plasma membrane, protein complex, terminal bouton ATP binding, copper ion binding, extracellular ATP-gated cation channel activity, ion channel activity, lipopolysaccharide binding, magnesium ion binding, protein homodimerization activity, purinergic nucleotide receptor activity, receptor binding, scaffold protein binding, zinc ion binding Human P2RY1 BHF-UCL UniProtKB {GO:0010469=GO_REF:0000019, GO:0005886=GO_REF:0000024, GO:0060406=GO_REF:0000019, GO:0007200=PMID:8630005, GO:0007204=GO_REF:0000024, GO:0007193=GO_REF:0000019, GO:0030425=GO_REF:0000024, GO:0042312=GO_REF:0000019, GO:0043270=GO_REF:0000019, GO:0016323=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0045211=GO_REF:0000024, GO:0045944=GO_REF:0000019, GO:0097110=GO_REF:0000024, GO:0046887=GO_REF:0000019, GO:0004872=PMID:8630005, GO:0070374=GO_REF:0000024, GO:0046982=GO_REF:0000019, GO:0023019=GO_REF:0000024, GO:0007568=GO_REF:0000019, GO:0014069=GO_REF:0000024, GO:0030168=Reactome:REACT_798, GO:0031686=GO_REF:0000019, GO:0045032=GO_REF:0000019, GO:0010700=GO_REF:0000019, GO:0045031=GO_REF:0000019, GO:0070848=GO_REF:0000019, GO:0072659=GO_REF:0000024, GO:0005524=GO_REF:0000019, GO:0044297=GO_REF:0000024, GO:0019233=GO_REF:0000019, GO:0009612=GO_REF:0000019, GO:0051100=GO_REF:0000019, GO:0007186=GO_REF:0000024, GO:0043531=GO_REF:0000019, GO:0045028=GO_REF:0000024, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:8630005, GO:0007420=GO_REF:0000019, GO:0001934=GO_REF:0000024, GO:0032962=GO_REF:0000019, GO:0042755=GO_REF:0000019, GO:0007166=PMID:8630005} P47900 P2Y purinoceptor 1 protein 20120504 {GO:0010469=IEA, GO:0005886=ISS, GO:0060406=IEA, GO:0007200=TAS, GO:0007204=ISS, GO:0007193=IEA, GO:0030425=ISS, GO:0042312=IEA, GO:0043270=IEA, GO:0016323=IEA, GO:0016324=IEA, GO:0045211=ISS, GO:0045944=IEA, GO:0097110=ISS, GO:0046887=IEA, GO:0004872=TAS, GO:0070374=ISS, GO:0046982=IEA, GO:0023019=ISS, GO:0007568=IEA, GO:0014069=ISS, GO:0030168=TAS, GO:0031686=IEA, GO:0045032=IEA, GO:0010700=IEA, GO:0045031=IEA, GO:0070848=IEA, GO:0072659=ISS, GO:0005524=IEA, GO:0044297=ISS, GO:0019233=IEA, GO:0009612=IEA, GO:0051100=IEA, GO:0007186=ISS, GO:0043531=IEA, GO:0045028=ISS, GO:0007596=TAS, GO:0005887=TAS, GO:0007420=IEA, GO:0001934=ISS, GO:0032962=IEA, GO:0042755=IEA, GO:0007166=TAS} G-protein coupled receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, aging, blood coagulation, brain development, cell surface receptor signaling pathway, eating behavior, elevation of cytosolic calcium ion concentration, negative regulation of binding, negative regulation of norepinephrine secretion, phospholipase C-activating G-protein coupled receptor signaling pathway, platelet activation, positive regulation of ERK1 and ERK2 cascade, positive regulation of hormone secretion, positive regulation of inositol trisphosphate biosynthetic process, positive regulation of ion transport, positive regulation of penile erection, positive regulation of protein phosphorylation, positive regulation of transcription from RNA polymerase II promoter, protein localization to plasma membrane, regulation of receptor activity, regulation of vasodilation, response to growth factor stimulus, response to mechanical stimulus, sensory perception of pain, signal transduction involved in regulation of gene expression apical plasma membrane, basolateral plasma membrane, cell body, dendrite, integral to plasma membrane, plasma membrane, postsynaptic density, postsynaptic membrane A1 adenosine receptor binding, ADP binding, ADP-activated nucleotide receptor activity, ATP binding, ATP-activated nucleotide receptor activity, G-protein coupled purinergic nucleotide receptor activity, protein heterodimerization activity, receptor activity, scaffold protein binding Human UniProtKB:P49651 P2RY10 Reactome UniProtKB {GO:0005886=Reactome:REACT_22436, GO:0045028=GO_REF:0000002, GO:0016021=GO_REF:0000037} O00398 Putative P2Y purinoceptor 10 protein 20100217 {GO:0005886=TAS, GO:0045028=IEA, GO:0016021=IEA} integral to membrane, plasma membrane G-protein coupled purinergic nucleotide receptor activity Human P2RY11 GOC UniProtKB {GO:0023041=PMID:18048695, GO:0019722=PMID:18048695, GO:0005886=Reactome:REACT_22436, GO:0030594=PMID:18048695, GO:0007268=PMID:18048695, GO:0007200=PMID:9405388, GO:0006952=PMID:9405388, GO:0045031=PMID:18048695, GO:0071318=PMID:18048695, GO:0007190=PMID:9405388, GO:0007186=PMID:18048695, GO:0045028=GO_REF:0000002, GO:0005887=PMID:18048695, GO:0004872=PMID:9405388} Q96G91 P2Y purinoceptor 11 protein 20130413 {GO:0023041=IDA, GO:0019722=IDA, GO:0005886=TAS, GO:0030594=IDA, GO:0007268=IDA, GO:0007200=TAS, GO:0006952=TAS, GO:0045031=IDA, GO:0071318=IDA, GO:0007190=TAS, GO:0007186=IDA, GO:0045028=IEA, GO:0005887=IC, GO:0004872=TAS} G-protein coupled receptor signaling pathway, activation of adenylate cyclase activity, calcium-mediated signaling, cellular response to ATP, defense response, neuronal signal transduction, phospholipase C-activating G-protein coupled receptor signaling pathway, synaptic transmission integral to plasma membrane, plasma membrane ATP-activated nucleotide receptor activity, G-protein coupled purinergic nucleotide receptor activity, neurotransmitter receptor activity, receptor activity Human P2RY12 Reactome UniProtKB {GO:0005886=Reactome:REACT_22289, GO:0030168=Reactome:REACT_798, GO:0010700=GO_REF:0000019, GO:0005085=Reactome:REACT_20507, GO:0007599=PMID:11196645, GO:0070527=GO_REF:0000019, GO:0001609=GO_REF:0000019, GO:0043270=GO_REF:0000019, GO:0009925=GO_REF:0000019, GO:0016020=GO_REF:0000029, GO:0007596=Reactome:REACT_604, GO:0005901=GO_REF:0000019, GO:0030030=GO_REF:0000019, GO:0051924=GO_REF:0000019, GO:0070588=GO_REF:0000019, GO:0043491=GO_REF:0000019, GO:0007188=GO_REF:0000019, GO:0045596=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0001621=GO_REF:0000019, GO:0071805=GO_REF:0000019, GO:0009897=GO_REF:0000019} Q9H244 P2Y purinoceptor 12 protein 20100217 {GO:0005886=TAS, GO:0030168=TAS, GO:0010700=IEA, GO:0005085=TAS, GO:0007599=NAS, GO:0070527=IEA, GO:0001609=IEA, GO:0043270=IEA, GO:0009925=IEA, GO:0016020=NAS, GO:0007596=TAS, GO:0005901=IEA, GO:0030030=IEA, GO:0051924=IEA, GO:0070588=IEA, GO:0043491=IEA, GO:0007188=IEA, GO:0045596=IEA, GO:0016021=IEA, GO:0001621=IEA, GO:0071805=IEA, GO:0009897=IEA} adenylate cyclase-modulating G-protein coupled receptor signaling pathway, blood coagulation, calcium ion transmembrane transport, cell projection organization, hemostasis, negative regulation of cell differentiation, negative regulation of norepinephrine secretion, platelet activation, platelet aggregation, positive regulation of ion transport, potassium ion transmembrane transport, protein kinase B signaling cascade, regulation of calcium ion transport basal plasma membrane, caveola, external side of plasma membrane, integral to membrane, membrane, plasma membrane ADP receptor activity, G-protein coupled adenosine receptor activity, guanyl-nucleotide exchange factor activity Human P2RY13 Reactome UniProtKB {GO:0008150=GO_REF:0000015, GO:0005886=Reactome:REACT_22289, GO:0045028=GO_REF:0000019, GO:0005783=GO_REF:0000019, GO:0016021=GO_REF:0000029} Q9BPV8 P2Y purinoceptor 13 protein 20100217 {GO:0008150=ND, GO:0005886=TAS, GO:0045028=IEA, GO:0005783=IEA, GO:0016021=NAS} biological_process endoplasmic reticulum, integral to membrane, plasma membrane G-protein coupled purinergic nucleotide receptor activity Human P2RY2 Reactome UniProtKB {GO:0005886=Reactome:REACT_22436, GO:0005887=PMID:8159738, GO:0045028=GO_REF:0000002, GO:0007200=PMID:8159738, GO:0006873=PMID:8159738, GO:0004872=PMID:7779087, GO:0070257=GO_REF:0000019} P41231 P2Y purinoceptor 2 protein 20100217 {GO:0005886=TAS, GO:0005887=TAS, GO:0045028=IEA, GO:0007200=TAS, GO:0006873=TAS, GO:0004872=TAS, GO:0070257=IEA} cellular ion homeostasis, phospholipase C-activating G-protein coupled receptor signaling pathway, positive regulation of mucus secretion integral to plasma membrane, plasma membrane G-protein coupled purinergic nucleotide receptor activity, receptor activity Human P2RY4 Reactome UniProtKB {GO:0030321=GO_REF:0000019, GO:0016323=GO_REF:0000019, GO:0015065=PMID:8537335, GO:0016324=GO_REF:0000019, GO:0005886=Reactome:REACT_22289, GO:0005887=PMID:8537336, GO:0045028=GO_REF:0000002, GO:0007200=PMID:8537336, GO:0007204=PMID:8537335, GO:0045030=GO_REF:0000019, GO:0005524=GO_REF:0000019} P51582 P2Y purinoceptor 4 protein 20100217 {GO:0030321=IEA, GO:0016323=IEA, GO:0015065=TAS, GO:0016324=IEA, GO:0005886=TAS, GO:0005887=TAS, GO:0045028=IEA, GO:0007200=TAS, GO:0007204=TAS, GO:0045030=IEA, GO:0005524=IEA} elevation of cytosolic calcium ion concentration, phospholipase C-activating G-protein coupled receptor signaling pathway, transepithelial chloride transport apical plasma membrane, basolateral plasma membrane, integral to plasma membrane, plasma membrane ATP binding, G-protein coupled purinergic nucleotide receptor activity, UTP-activated nucleotide receptor activity, uridine nucleotide receptor activity Human P2RY6 Reactome UniProtKB {GO:0030321=GO_REF:0000019, GO:0016323=GO_REF:0000019, GO:0045029=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0005886=Reactome:REACT_22436, GO:0004930=PMID:8670200, GO:0005887=PMID:8670200, GO:0045028=GO_REF:0000002, GO:0007200=PMID:8670200, GO:0016021=GO_REF:0000038, GO:0014911=GO_REF:0000019} Q15077 P2Y purinoceptor 6 protein 20100217 {GO:0030321=IEA, GO:0016323=IEA, GO:0045029=IEA, GO:0016324=IEA, GO:0005886=TAS, GO:0004930=TAS, GO:0005887=TAS, GO:0045028=IEA, GO:0007200=TAS, GO:0016021=IEA, GO:0014911=IEA} phospholipase C-activating G-protein coupled receptor signaling pathway, positive regulation of smooth muscle cell migration, transepithelial chloride transport apical plasma membrane, basolateral plasma membrane, integral to membrane, integral to plasma membrane, plasma membrane G-protein coupled purinergic nucleotide receptor activity, G-protein coupled receptor activity, UDP-activated nucleotide receptor activity Human P2RY8 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0045028=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q86VZ1 P2Y purinoceptor 8 protein 20130413 {GO:0005886=IEA, GO:0045028=IEA, GO:0016021=IEA} integral to membrane, plasma membrane G-protein coupled purinergic nucleotide receptor activity Human UniProtKB-SubCell:SL-0039 P4HA1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0031418=GO_REF:0000037, GO:0005506=GO_REF:0000002, GO:0005783=GO_REF:0000052, GO:0030199=GO_REF:0000019, GO:0018401=GO_REF:0000019, GO:0005788=GO_REF:0000039, GO:0004656=GO_REF:0000003, GO:0016702=GO_REF:0000037, GO:0043231=GO_REF:0000052} P13674 Prolyl 4-hydroxylase subunit alpha-1 protein 20100326 {GO:0005739=IDA, GO:0031418=IEA, GO:0005506=IEA, GO:0005783=IDA, GO:0030199=IEA, GO:0018401=IEA, GO:0005788=IEA, GO:0004656=IEA, GO:0016702=IEA, GO:0043231=IDA} collagen fibril organization, peptidyl-proline hydroxylation to 4-hydroxy-L-proline endoplasmic reticulum, endoplasmic reticulum lumen, intracellular membrane-bounded organelle, mitochondrion L-ascorbic acid binding, iron ion binding, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, procollagen-proline 4-dioxygenase activity Human P4HA2 UniProtKB UniProtKB {GO:0031418=GO_REF:0000037, GO:0005506=GO_REF:0000002, GO:0005783=GO_REF:0000002, GO:0018401=GO_REF:0000019, GO:0009055=PMID:9211872, GO:0005788=GO_REF:0000039, GO:0004656=GO_REF:0000003, GO:0016702=GO_REF:0000037} O15460 Prolyl 4-hydroxylase subunit alpha-2 protein 20060428 {GO:0031418=IEA, GO:0005506=IEA, GO:0005783=IEA, GO:0018401=IEA, GO:0009055=TAS, GO:0005788=IEA, GO:0004656=IEA, GO:0016702=IEA} peptidyl-proline hydroxylation to 4-hydroxy-L-proline endoplasmic reticulum, endoplasmic reticulum lumen L-ascorbic acid binding, electron carrier activity, iron ion binding, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, procollagen-proline 4-dioxygenase activity Human P4HA3 UniProtKB UniProtKB {GO:0005581=GO_REF:0000038, GO:0031418=GO_REF:0000037, GO:0005506=GO_REF:0000002, GO:0005783=GO_REF:0000002, GO:0005788=GO_REF:0000039, GO:0004656=GO_REF:0000003, GO:0016702=GO_REF:0000037} Q7Z4N8 Prolyl 4-hydroxylase subunit alpha-3 protein 20130413 {GO:0005581=IEA, GO:0031418=IEA, GO:0005506=IEA, GO:0005783=IEA, GO:0005788=IEA, GO:0004656=IEA, GO:0016702=IEA} collagen, endoplasmic reticulum, endoplasmic reticulum lumen L-ascorbic acid binding, iron ion binding, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, procollagen-proline 4-dioxygenase activity Human UniProtKB-SubCell:SL-0096 P4HB GOC UniProtKB {GO:0005515=PMID:17055437, GO:0006629=Reactome:REACT_602, GO:0042470=GO_REF:0000039, GO:0005793=PMID:15308636, GO:0046982=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0009986=PMID:12493773, GO:0005783=GO_REF:0000052, GO:0006662=GO_REF:0000002, GO:0015035=GO_REF:0000002, GO:0009055=GO_REF:0000002, GO:0003756=GO_REF:0000003, GO:0004656=PMID:7753822, GO:0005576=PMID:14718574, GO:0044281=Reactome:REACT_111217, GO:0006457=PMID:2846539, GO:0030198=Reactome:REACT_118779, GO:0018401=PMID:7753822, GO:0042157=Reactome:REACT_6841, GO:0005788=Reactome:REACT_121152, GO:0045454=GO_REF:0000002, GO:0016853=GO_REF:0000002} P07237 Protein disulfide-isomerase protein 20130413 {GO:0005515=IPI, GO:0006629=TAS, GO:0042470=IEA, GO:0005793=IDA, GO:0046982=IEA, GO:0005886=IEA, GO:0009986=IDA, GO:0005783=IDA, GO:0006662=IEA, GO:0015035=IEA, GO:0009055=IEA, GO:0003756=IEA, GO:0004656=IDA, GO:0005576=NAS, GO:0044281=TAS, GO:0006457=TAS, GO:0030198=TAS, GO:0018401=IDA, GO:0042157=TAS, GO:0005788=TAS, GO:0045454=IEA, GO:0016853=IEA} cell redox homeostasis, extracellular matrix organization, glycerol ether metabolic process, lipid metabolic process, lipoprotein metabolic process, peptidyl-proline hydroxylation to 4-hydroxy-L-proline, protein folding, small molecule metabolic process cell surface, endoplasmic reticulum, endoplasmic reticulum lumen, endoplasmic reticulum-Golgi intermediate compartment, extracellular region, melanosome, plasma membrane electron carrier activity, isomerase activity, procollagen-proline 4-dioxygenase activity, protein binding, protein disulfide isomerase activity, protein disulfide oxidoreductase activity, protein heterodimerization activity Human P4HTM UniProtKB UniProtKB {GO:0031418=GO_REF:0000037, GO:0005506=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0016706=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0016702=GO_REF:0000037} Q9NXG6 Transmembrane prolyl 4-hydroxylase protein 20130413 {GO:0031418=IEA, GO:0005506=IEA, GO:0005509=IEA, GO:0005789=IEA, GO:0016706=IEA, GO:0016021=IEA, GO:0016702=IEA} endoplasmic reticulum membrane, integral to membrane L-ascorbic acid binding, calcium ion binding, iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Human UniProtKB-SubCell:SL-0097 PA2G4 IntAct UniProtKB {GO:0005515=PMID:16254079, GO:0003700=PMID:15073182, GO:0008283=PMID:7556453, GO:0009987=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0006364=GO_REF:0000037, GO:0005730=PMID:19037095, GO:0005634=PMID:15073182, GO:0003677=PMID:15073182, GO:0006351=GO_REF:0000037, GO:0006417=GO_REF:0000037, GO:0005737=PMID:19037095, GO:0016787=GO_REF:0000038, GO:0030529=GO_REF:0000037, GO:0007050=PMID:7556453, GO:0045892=PMID:15073182, GO:0031625=PMID:19037095} Q9UQ80 Proliferation-associated protein 2G4 protein 20130415 {GO:0005515=IPI, GO:0003700=IDA, GO:0008283=TAS, GO:0009987=IEA, GO:0003723=IEA, GO:0006364=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IDA, GO:0006351=IEA, GO:0006417=IEA, GO:0005737=IDA, GO:0016787=IEA, GO:0030529=IEA, GO:0007050=TAS, GO:0045892=IDA, GO:0031625=IPI} cell cycle arrest, cell proliferation, cellular process, negative regulation of transcription, DNA-dependent, rRNA processing, regulation of translation, transcription, DNA-dependent cytoplasm, nucleolus, nucleus, ribonucleoprotein complex DNA binding, RNA binding, hydrolase activity, protein binding, sequence-specific DNA binding transcription factor activity, ubiquitin protein ligase binding Human UniProtKB:Q96ST3 PAAF1 IntAct UniProtKB {GO:0005515=PMID:19490896, GO:0000502=GO_REF:0000037, GO:0019048=GO_REF:0000037} Q9BRP4 Proteasomal ATPase-associated factor 1 protein 20130415 {GO:0005515=IPI, GO:0000502=IEA, GO:0019048=IEA} virus-host interaction proteasome complex protein binding Human UniProtKB:P62195 PABPC1 GOC UniProtKB {GO:0005515=PMID:21981923, GO:0010467=Reactome:REACT_71, GO:0010494=PMID:21940797, GO:0003723=GO_REF:0000002, GO:0005634=PMID:21940797, GO:0031047=GO_REF:0000024, GO:0071013=PMID:11991638, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_75917, GO:0005737=GO_REF:0000052, GO:0000166=GO_REF:0000002, GO:0000184=Reactome:REACT_75886, GO:0008143=PMID:16804161, GO:0048255=PMID:11997512, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639, GO:0006378=PMID:2885805, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0060213=GO_REF:0000024, GO:0045727=PMID:11997512, GO:0008494=PMID:11997512, GO:0008022=PMID:15663938, GO:0003676=GO_REF:0000002, GO:0000398=PMID:11991638, GO:1900153=GO_REF:0000024, GO:0030529=PMID:17289661, GO:2000623=PMID:18447585, GO:0044267=Reactome:REACT_17015} P11940 Polyadenylate-binding protein 1 protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0010494=IDA, GO:0003723=IEA, GO:0005634=IDA, GO:0031047=ISS, GO:0071013=IDA, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0000166=IEA, GO:0000184=TAS, GO:0008143=IDA, GO:0048255=TAS, GO:0000289=TAS, GO:0000288=TAS, GO:0006378=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0060213=ISS, GO:0045727=TAS, GO:0008494=TAS, GO:0008022=IPI, GO:0003676=IEA, GO:0000398=IC, GO:1900153=ISS, GO:0030529=IDA, GO:2000623=IDA, GO:0044267=TAS} RNA metabolic process, cellular protein metabolic process, gene expression, gene silencing by RNA, mRNA metabolic process, mRNA polyadenylation, mRNA splicing, via spliceosome, mRNA stabilization, negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, nuclear-transcribed mRNA poly(A) tail shortening, positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, positive regulation of nuclear-transcribed mRNA poly(A) tail shortening, positive regulation of translation, translation, translational initiation catalytic step 2 spliceosome, cytoplasm, cytoplasmic stress granule, cytosol, nucleus, ribonucleoprotein complex RNA binding, nucleic acid binding, nucleotide binding, poly(A) RNA binding, protein C-terminus binding, protein binding, translation activator activity Human PABPC1L InterPro UniProtKB {GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000002} Q4VY17 Polyadenylate-binding protein 1-like protein 20130413 {GO:0000166=IEA, GO:0003723=IEA} RNA binding, nucleotide binding Human InterPro:IPR006515 PABPC1L2A UniProtKB UniProtKB {GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037} Q5JQF8 Polyadenylate-binding protein 1-like 2 protein 20130413 {GO:0000166=IEA, GO:0003723=IEA} RNA binding, nucleotide binding Human UniProtKB-KW:KW-0694 PABPC3 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0000166=GO_REF:0000002, GO:0016071=PMID:11328870, GO:0003723=GO_REF:0000002, GO:0008143=PMID:11328870, GO:0003676=GO_REF:0000002} Q9H361 Polyadenylate-binding protein 3 protein 20111111 {GO:0005737=IDA, GO:0000166=IEA, GO:0016071=NAS, GO:0003723=IEA, GO:0008143=IDA, GO:0003676=IEA} mRNA metabolic process cytoplasm RNA binding, nucleic acid binding, nucleotide binding, poly(A) RNA binding Human PABPC4 HPA UniProtKB {GO:0005515=PMID:11369516, GO:0006396=PMID:8524242, GO:0010494=PMID:21940797, GO:0003723=GO_REF:0000002, GO:0017130=PMID:8524242, GO:0005634=PMID:21940797, GO:0003676=GO_REF:0000002, GO:0006412=PMID:8524242, GO:0006401=PMID:8524242, GO:0008266=PMID:8524242, GO:0005737=GO_REF:0000052, GO:0000166=GO_REF:0000002, GO:0007596=PMID:9030741, GO:0030529=PMID:17289661, GO:0008143=PMID:8524242} Q13310 Polyadenylate-binding protein 4 protein 20101115 {GO:0005515=IPI, GO:0006396=TAS, GO:0010494=IDA, GO:0003723=IEA, GO:0017130=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0006412=TAS, GO:0006401=TAS, GO:0008266=IDA, GO:0005737=IDA, GO:0000166=IEA, GO:0007596=TAS, GO:0030529=IDA, GO:0008143=IDA} RNA catabolic process, RNA processing, blood coagulation, translation cytoplasm, cytoplasmic stress granule, nucleus, ribonucleoprotein complex RNA binding, nucleic acid binding, nucleotide binding, poly(A) RNA binding, poly(C) RNA binding, poly(U) RNA binding, protein binding Human PABPC4L UniProtKB UniProtKB {GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037} P0CB38 Polyadenylate-binding protein 4-like protein 20130413 {GO:0000166=IEA, GO:0003723=IEA} RNA binding, nucleotide binding Human UniProtKB-KW:KW-0694 PABPC5 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0003676=GO_REF:0000002} Q96DU9 Polyadenylate-binding protein 5 protein 20130413 {GO:0005737=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0003676=IEA} cytoplasm RNA binding, nucleic acid binding, nucleotide binding Human UniProtKB-SubCell:SL-0086 PABPN1 HPA UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:11371506, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0006396=PMID:9462747, GO:0019054=Reactome:REACT_6222, GO:0006366=Reactome:REACT_1366, GO:0003723=GO_REF:0000037, GO:0031124=Reactome:REACT_1849, GO:0019058=Reactome:REACT_6167, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0006936=PMID:9462747, GO:0046778=Reactome:REACT_6173, GO:0000166=GO_REF:0000002, GO:0016973=PMID:19364924, GO:0000398=Reactome:REACT_467, GO:0019048=Reactome:REACT_6323, GO:0030529=PMID:17289661, GO:0005654=Reactome:REACT_6287} Q86U42 Polyadenylate-binding protein 2 protein 20080205 {GO:0008380=TAS, GO:0005515=IPI, GO:0010467=TAS, GO:0006369=TAS, GO:0006396=TAS, GO:0019054=TAS, GO:0006366=TAS, GO:0003723=IEA, GO:0031124=TAS, GO:0019058=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0005737=IDA, GO:0006936=TAS, GO:0046778=TAS, GO:0000166=IEA, GO:0016973=IMP, GO:0000398=TAS, GO:0019048=TAS, GO:0030529=IDA, GO:0005654=TAS} RNA processing, RNA splicing, gene expression, mRNA 3'-end processing, mRNA splicing, via spliceosome, modification by virus of host mRNA processing, modulation by virus of host cellular process, muscle contraction, poly(A)+ mRNA export from nucleus, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter, viral infectious cycle, virus-host interaction cytoplasm, nucleolus, nucleoplasm, nucleus, ribonucleoprotein complex RNA binding, nucleic acid binding, nucleotide binding, protein binding Human PABPN1L UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037} A6NDY0 Embryonic polyadenylate-binding protein 2 protein 20130413 {GO:0005737=IEA, GO:0000166=IEA, GO:0003723=IEA} cytoplasm RNA binding, nucleotide binding Human UniProtKB-SubCell:SL-0086 PACRG ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0097225=GO_REF:0000019, GO:0007286=GO_REF:0000019, GO:0044297=GO_REF:0000019} Q96M98 Parkin coregulated gene protein protein 20130413 {GO:0005739=IEA, GO:0097225=IEA, GO:0007286=IEA, GO:0044297=IEA} spermatid development cell body, mitochondrion, sperm midpiece Human Ensembl:ENSMUSP00000044376 PACRGL null null {} null null null null {} null null null PACS1 BHF-UCL UniProtKB {GO:0005515=PMID:10707087, GO:0030137=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0016032=Reactome:REACT_6185, GO:0044325=PMID:15692563, GO:0050690=Reactome:REACT_11149, GO:0005829=Reactome:REACT_11229, GO:0000042=GO_REF:0000019} Q6VY07 Phosphofurin acidic cluster sorting protein 1 protein 20120116 {GO:0005515=IPI, GO:0030137=IEA, GO:0019048=IEA, GO:0016032=TAS, GO:0044325=IPI, GO:0050690=TAS, GO:0005829=TAS, GO:0000042=IEA} protein targeting to Golgi, regulation of defense response to virus by virus, viral reproduction, virus-host interaction COPI-coated vesicle, cytosol ion channel binding, protein binding Human UniProtKB:Q13563 PACS2 BHF-UCL UniProtKB {GO:0005739=GO_REF:0000039, GO:0005783=PMID:15692563, GO:0019048=GO_REF:0000037, GO:0005788=GO_REF:0000039, GO:0006915=GO_REF:0000037} Q86VP3 Phosphofurin acidic cluster sorting protein 2 protein 20120116 {GO:0005739=IEA, GO:0005783=IDA, GO:0019048=IEA, GO:0005788=IEA, GO:0006915=IEA} apoptotic process, virus-host interaction endoplasmic reticulum, endoplasmic reticulum lumen, mitochondrion Human PACSIN1 BHF-UCL UniProtKB {GO:0008092=GO_REF:0000019, GO:0048471=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000024, GO:0030137=GO_REF:0000019, GO:0097320=PMID:19549836, GO:0045202=GO_REF:0000024, GO:0032587=GO_REF:0000024, GO:0072657=GO_REF:0000024, GO:0048488=GO_REF:0000024, GO:0005829=GO_REF:0000039, GO:0005737=GO_REF:0000054, GO:0005543=PMID:19549836, GO:0048812=GO_REF:0000024, GO:0045806=GO_REF:0000019, GO:0043679=GO_REF:0000024, GO:0090002=GO_REF:0000024, GO:0030659=GO_REF:0000039, GO:1900006=GO_REF:0000024} Q9BY11 Protein kinase C and casein kinase substrate in neurons protein 1 protein 20120808 {GO:0008092=IEA, GO:0048471=ISS, GO:0030054=IEA, GO:0005886=ISS, GO:0030137=IEA, GO:0097320=IDA, GO:0045202=ISS, GO:0032587=ISS, GO:0072657=ISS, GO:0048488=ISS, GO:0005829=IEA, GO:0005737=IDA, GO:0005543=IDA, GO:0048812=ISS, GO:0045806=IEA, GO:0043679=ISS, GO:0090002=ISS, GO:0030659=IEA, GO:1900006=ISS} establishment of protein localization to plasma membrane, membrane tubulation, negative regulation of endocytosis, neuron projection morphogenesis, positive regulation of dendrite development, protein localization to membrane, synaptic vesicle endocytosis COPI-coated vesicle, axon terminus, cell junction, cytoplasm, cytoplasmic vesicle membrane, cytosol, perinuclear region of cytoplasm, plasma membrane, ruffle membrane, synapse cytoskeletal protein binding, phospholipid binding Human UniProtKB:Q9Z0W5 PACSIN2 PINC UniProtKB {GO:0008092=GO_REF:0000019, GO:0005215=PMID:10431838, GO:0005737=PMID:10431838, GO:0030036=PMID:10431838, GO:0097320=GO_REF:0000024, GO:0005901=PMID:21610094, GO:0072584=PMID:21610094, GO:0045806=GO_REF:0000019, GO:0048858=GO_REF:0000024, GO:0019898=GO_REF:0000024, GO:0070836=PMID:21610094, GO:0005829=GO_REF:0000019} Q9UNF0 Protein kinase C and casein kinase substrate in neurons protein 2 protein 20030904 {GO:0008092=IEA, GO:0005215=TAS, GO:0005737=TAS, GO:0030036=TAS, GO:0097320=ISS, GO:0005901=IDA, GO:0072584=IMP, GO:0045806=IEA, GO:0048858=ISS, GO:0019898=ISS, GO:0070836=IMP, GO:0005829=IEA} actin cytoskeleton organization, caveola assembly, caveolin-mediated endocytosis, cell projection morphogenesis, membrane tubulation, negative regulation of endocytosis caveola, cytoplasm, cytosol, extrinsic to membrane cytoskeletal protein binding, transporter activity Human PACSIN3 BHF-UCL UniProtKB {GO:0005515=PMID:14679214, GO:0008092=GO_REF:0000024, GO:0051044=PMID:15280379, GO:0005737=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0045806=GO_REF:0000024, GO:0006897=GO_REF:0000037} Q9UKS6 Protein kinase C and casein kinase substrate in neurons protein 3 protein 20081118 {GO:0005515=IPI, GO:0008092=ISS, GO:0051044=IMP, GO:0005737=ISS, GO:0005886=IEA, GO:0045806=ISS, GO:0006897=IEA} endocytosis, negative regulation of endocytosis, positive regulation of membrane protein ectodomain proteolysis cytoplasm, plasma membrane cytoskeletal protein binding, protein binding Human PADI1 UniProtKB UniProtKB {GO:0018101=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0004668=GO_REF:0000003, GO:0006464=GO_REF:0000002} Q9ULC6 Protein-arginine deiminase type-1 protein 20130413 {GO:0018101=IEA, GO:0005737=IEA, GO:0005509=IEA, GO:0004668=IEA, GO:0006464=IEA} cellular protein modification process, peptidyl-citrulline biosynthetic process from peptidyl-arginine cytoplasm calcium ion binding, protein-arginine deiminase activity Human UniProtKB-SubCell:SL-0086 PADI2 UniProtKB UniProtKB {GO:0018101=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0004668=GO_REF:0000003, GO:0006464=GO_REF:0000002} Q9Y2J8 Protein-arginine deiminase type-2 protein 20130413 {GO:0018101=IEA, GO:0005737=IEA, GO:0005509=IEA, GO:0004668=IEA, GO:0006464=IEA} cellular protein modification process, peptidyl-citrulline biosynthetic process from peptidyl-arginine cytoplasm calcium ion binding, protein-arginine deiminase activity Human UniProtKB-SubCell:SL-0086 PADI3 HPA UniProtKB {GO:0018101=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0005509=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0004668=GO_REF:0000003} Q9ULW8 Protein-arginine deiminase type-3 protein 20111111 {GO:0018101=IEA, GO:0005737=IDA, GO:0005509=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0004668=IEA} peptidyl-citrulline biosynthetic process from peptidyl-arginine cytoplasm, nucleolus, nucleus calcium ion binding, protein-arginine deiminase activity Human PADI4 HPA UniProtKB {GO:0018101=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0005509=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0004668=GO_REF:0000003, GO:0006351=GO_REF:0000037, GO:0006464=PMID:10488123, GO:0016568=GO_REF:0000037} Q9UM07 Protein-arginine deiminase type-4 protein 20090616 {GO:0018101=IEA, GO:0006355=IEA, GO:0005737=IDA, GO:0005509=IEA, GO:0005634=IEA, GO:0004668=IEA, GO:0006351=IEA, GO:0006464=TAS, GO:0016568=IEA} cellular protein modification process, chromatin modification, peptidyl-citrulline biosynthetic process from peptidyl-arginine, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus calcium ion binding, protein-arginine deiminase activity Human PAEP InterPro UniProtKB {GO:0036094=GO_REF:0000002, GO:0006810=GO_REF:0000002, GO:0007275=PMID:3194393, GO:0005576=GO_REF:0000039} Q5T6T6 Glycodelin protein 20130413 {GO:0036094=IEA, GO:0006810=IEA, GO:0007275=TAS, GO:0005576=IEA} multicellular organismal development, transport extracellular region small molecule binding Human InterPro:IPR002447 PAF1 HPA UniProtKB {GO:0005515=PMID:20541477, GO:0006378=PMID:21329879, GO:0033523=PMID:16307923, GO:0000993=PMID:15923622, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000122=GO_REF:0000024, GO:0045749=PMID:15923622, GO:0001711=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0005739=GO_REF:0000052, GO:0071222=GO_REF:0000024, GO:0045638=PMID:20541477, GO:0003682=GO_REF:0000019, GO:0019827=GO_REF:0000019, GO:0045944=PMID:20178742, GO:0032968=PMID:20178742, GO:0016593=PMID:20178742, GO:0016055=GO_REF:0000037, GO:0010390=PMID:16307923, GO:0031442=PMID:21329879} Q8N7H5 RNA polymerase II-associated factor 1 homolog protein 20111111 {GO:0005515=IPI, GO:0006378=IMP, GO:0033523=IDA, GO:0000993=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0000122=ISS, GO:0045749=IMP, GO:0001711=ISS, GO:0006351=IEA, GO:0005739=IDA, GO:0071222=ISS, GO:0045638=IDA, GO:0003682=IEA, GO:0019827=IEA, GO:0045944=IDA, GO:0032968=IDA, GO:0016593=IDA, GO:0016055=IEA, GO:0010390=IDA, GO:0031442=IMP} Wnt receptor signaling pathway, cellular response to lipopolysaccharide, endodermal cell fate commitment, histone H2B ubiquitination, histone monoubiquitination, mRNA polyadenylation, negative regulation of S phase of mitotic cell cycle, negative regulation of myeloid cell differentiation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of mRNA 3'-end processing, positive regulation of transcription elongation from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter, stem cell maintenance, transcription, DNA-dependent Cdc73/Paf1 complex, mitochondrion, nucleolus, nucleus RNA polymerase II core binding, chromatin binding, protein binding Human PAFAH1B1 HPA UniProtKB {GO:0005515=PMID:20360068, GO:0000235=PMID:11940666, GO:0008017=PMID:10729324, GO:0051219=GO_REF:0000024, GO:0000236=Reactome:REACT_682, GO:0008090=PMID:10729324, GO:0009306=GO_REF:0000019, GO:0034452=PMID:11056532, GO:0017145=GO_REF:0000019, GO:0000132=PMID:11056532, GO:0019226=PMID:10729324, GO:0032403=GO_REF:0000019, GO:0042803=GO_REF:0000024, GO:0007405=PMID:10729324, GO:0046329=GO_REF:0000019, GO:0043274=PMID:8028668, GO:0047496=PMID:10729324, GO:0031023=PMID:11163258, GO:0050885=PMID:9063735, GO:0043025=GO_REF:0000019, GO:0006810=GO_REF:0000038, GO:0007611=GO_REF:0000024, GO:0032319=PMID:10729324, GO:0005938=PMID:11940666, GO:0021895=GO_REF:0000019, GO:0031965=GO_REF:0000039, GO:0005813=GO_REF:0000052, GO:0021540=PMID:9063735, GO:0016042=GO_REF:0000037, GO:0045505=GO_REF:0000019, GO:0045931=GO_REF:0000019, GO:0045502=PMID:11889140, GO:0010977=GO_REF:0000019, GO:0000776=PMID:11940666, GO:0000278=Reactome:REACT_152, GO:0051081=GO_REF:0000019, GO:0051301=GO_REF:0000038, GO:0008344=PMID:9063735, GO:0001675=GO_REF:0000024, GO:0048471=GO_REF:0000024, GO:0021987=PMID:9063735, GO:0030036=PMID:10729324, GO:0007097=GO_REF:0000019, GO:0045773=GO_REF:0000019, GO:0007268=PMID:10729324, GO:0005634=GO_REF:0000052, GO:0005635=PMID:11940666, GO:0005829=PMID:8028668, GO:0030426=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0051660=GO_REF:0000019, GO:0001961=GO_REF:0000019, GO:0000086=Reactome:REACT_2203, GO:0000087=Reactome:REACT_910, GO:0007017=PMID:11940666, GO:0008201=PMID:8028668, GO:0031252=GO_REF:0000024, GO:0046469=PMID:8028668, GO:0005871=GO_REF:0000019, GO:0005875=PMID:11889140, GO:0001667=GO_REF:0000019, GO:0005874=GO_REF:0000038, GO:0005730=GO_REF:0000052, GO:0000226=PMID:10729324, GO:0031513=GO_REF:0000024, GO:0031512=GO_REF:0000024, GO:0021819=GO_REF:0000024, GO:0031982=GO_REF:0000019, GO:0048854=PMID:9063735, GO:0033267=GO_REF:0000019, GO:0021766=GO_REF:0000024, GO:0007067=GO_REF:0000038, GO:0036035=GO_REF:0000019, GO:0016787=GO_REF:0000038, GO:0001764=PMID:10729324, GO:0000090=Reactome:REACT_1275} P43034 Platelet-activating factor acetylhydrolase IB subunit alpha protein 20101115 {GO:0005515=IPI, GO:0000235=IDA, GO:0008017=ISS, GO:0051219=ISS, GO:0000236=TAS, GO:0008090=ISS, GO:0009306=IEA, GO:0034452=ISS, GO:0017145=IEA, GO:0000132=IMP, GO:0019226=ISS, GO:0032403=IEA, GO:0042803=ISS, GO:0007405=ISS, GO:0046329=IEA, GO:0043274=ISS, GO:0047496=ISS, GO:0031023=IMP, GO:0050885=IMP, GO:0043025=IEA, GO:0006810=IEA, GO:0007611=ISS, GO:0032319=ISS, GO:0005938=IDA, GO:0021895=IEA, GO:0031965=IEA, GO:0005813=IDA, GO:0021540=IMP, GO:0016042=IEA, GO:0045505=IEA, GO:0045931=IEA, GO:0045502=IDA, GO:0010977=IEA, GO:0000776=IDA, GO:0000278=TAS, GO:0051081=IEA, GO:0051301=IEA, GO:0008344=IMP, GO:0001675=ISS, GO:0048471=ISS, GO:0021987=IMP, GO:0030036=ISS, GO:0007097=IEA, GO:0045773=IEA, GO:0007268=ISS, GO:0005634=IDA, GO:0005635=IDA, GO:0005829=ISS, GO:0030426=IEA, GO:0005737=IDA, GO:0051660=IEA, GO:0001961=IEA, GO:0000086=TAS, GO:0000087=TAS, GO:0007017=IDA, GO:0008201=ISS, GO:0031252=ISS, GO:0046469=ISS, GO:0005871=IEA, GO:0005875=IDA, GO:0001667=IEA, GO:0005874=IEA, GO:0005730=IDA, GO:0000226=ISS, GO:0031513=ISS, GO:0031512=ISS, GO:0021819=ISS, GO:0031982=IEA, GO:0048854=IMP, GO:0033267=IEA, GO:0021766=ISS, GO:0007067=IEA, GO:0036035=IEA, GO:0016787=IEA, GO:0001764=ISS, GO:0000090=TAS} G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, acrosome assembly, actin cytoskeleton organization, adult locomotory behavior, ameboidal cell migration, brain morphogenesis, cell division, cerebral cortex development, cerebral cortex neuron differentiation, corpus callosum morphogenesis, establishment of centrosome localization, establishment of mitotic spindle orientation, hippocampus development, layer formation in cerebral cortex, learning or memory, lipid catabolic process, microtubule cytoskeleton organization, microtubule organizing center organization, microtubule-based process, mitosis, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, negative regulation of JNK cascade, negative regulation of neuron projection development, neuroblast proliferation, neuromuscular process controlling balance, neuron migration, nuclear envelope disassembly, nuclear migration, osteoclast development, platelet activating factor metabolic process, positive regulation of axon extension, positive regulation of cytokine-mediated signaling pathway, positive regulation of mitotic cell cycle, protein secretion, regulation of Rho GTPase activity, retrograde axon cargo transport, stem cell division, synaptic transmission, transmission of nerve impulse, transport, vesicle transport along microtubule astral microtubule, axon part, cell cortex, cell leading edge, centrosome, cytoplasm, cytosol, growth cone, kinesin complex, kinetochore, microtubule, microtubule associated complex, motile primary cilium, neuronal cell body, nonmotile primary cilium, nuclear envelope, nuclear membrane, nucleolus, nucleus, perinuclear region of cytoplasm, vesicle dynactin binding, dynein binding, dynein intermediate chain binding, heparin binding, hydrolase activity, microtubule binding, phospholipase binding, phosphoprotein binding, protein binding, protein complex binding, protein homodimerization activity Human PAFAH1B2 BHF-UCL UniProtKB {GO:0006629=PMID:9144386, GO:0046982=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0003847=GO_REF:0000003, GO:0007283=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0016042=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0016787=GO_REF:0000002, GO:0007420=GO_REF:0000019, GO:0016239=PMID:22354037} P68402 Platelet-activating factor acetylhydrolase IB subunit beta protein 20120531 {GO:0006629=TAS, GO:0046982=IEA, GO:0005886=IDA, GO:0005730=IDA, GO:0003847=IEA, GO:0007283=IEA, GO:0042803=IEA, GO:0005829=IEA, GO:0016042=IEA, GO:0005737=IDA, GO:0016787=IEA, GO:0007420=IEA, GO:0016239=IMP} brain development, lipid catabolic process, lipid metabolic process, positive regulation of macroautophagy, spermatogenesis cytoplasm, cytosol, nucleolus, plasma membrane 1-alkyl-2-acetylglycerophosphocholine esterase activity, hydrolase activity, protein heterodimerization activity, protein homodimerization activity Human PAFAH1B3 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0006629=PMID:7669037, GO:0016042=GO_REF:0000037, GO:0046982=GO_REF:0000019, GO:0016787=GO_REF:0000002, GO:0007420=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0003847=GO_REF:0000003, GO:0007399=PMID:7669037, GO:0005829=GO_REF:0000019} Q15102 Platelet-activating factor acetylhydrolase IB subunit gamma protein 20130415 {GO:0005515=IPI, GO:0006629=TAS, GO:0016042=IEA, GO:0046982=IEA, GO:0016787=IEA, GO:0007420=IEA, GO:0007283=IEA, GO:0003847=IEA, GO:0007399=TAS, GO:0005829=IEA} brain development, lipid catabolic process, lipid metabolic process, nervous system development, spermatogenesis cytosol 1-alkyl-2-acetylglycerophosphocholine esterase activity, hydrolase activity, protein binding, protein heterodimerization activity Human UniProtKB:Q8TBB1 PAG1 Reactome UniProtKB {GO:0035556=PMID:10790433, GO:0005515=PMID:10790433, GO:0050852=Reactome:REACT_12526, GO:0007165=PMID:10790433, GO:0050863=PMID:10790433, GO:0007173=Reactome:REACT_9417, GO:0005886=Reactome:REACT_12640, GO:0005070=PMID:10790433, GO:0050868=GO_REF:0000019, GO:0045121=PMID:10790433, GO:0016021=GO_REF:0000037, GO:0042169=PMID:10790433} Q9NWQ8 Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 protein 20130213 {GO:0035556=IDA, GO:0005515=IPI, GO:0050852=TAS, GO:0007165=TAS, GO:0050863=IDA, GO:0007173=TAS, GO:0005886=TAS, GO:0005070=NAS, GO:0050868=IEA, GO:0045121=IDA, GO:0016021=IEA, GO:0042169=IDA} T cell receptor signaling pathway, epidermal growth factor receptor signaling pathway, intracellular signal transduction, negative regulation of T cell activation, regulation of T cell activation, signal transduction integral to membrane, membrane raft, plasma membrane SH2 domain binding, SH3/SH2 adaptor activity, protein binding Human PAGE1 PINC UniProtKB {GO:0006968=PMID:9651357} O75459 P antigen family member 1 protein 20030904 {GO:0006968=TAS} cellular defense response Human PAGE2 null null {} null null null null {} null null null PAGE5 null null {} null null null null {} null null null PAH BHF-UCL UniProtKB {GO:0034641=Reactome:REACT_13, GO:0006559=Reactome:REACT_1786, GO:0005506=GO_REF:0000002, GO:0009072=GO_REF:0000002, GO:0008652=PMID:3856322, GO:0004505=Reactome:REACT_2, GO:0042136=PMID:2872999, GO:0044281=Reactome:REACT_111217, GO:0016597=GO_REF:0000002, GO:0042423=PMID:2872999, GO:0005829=Reactome:REACT_2} P00439 Phenylalanine-4-hydroxylase protein 20080926 {GO:0034641=TAS, GO:0006559=TAS, GO:0005506=IEA, GO:0009072=IEA, GO:0008652=TAS, GO:0004505=EXP, GO:0042136=NAS, GO:0044281=TAS, GO:0016597=IEA, GO:0042423=NAS, GO:0005829=TAS} L-phenylalanine catabolic process, aromatic amino acid family metabolic process, catecholamine biosynthetic process, cellular amino acid biosynthetic process, cellular nitrogen compound metabolic process, neurotransmitter biosynthetic process, small molecule metabolic process cytosol amino acid binding, iron ion binding, phenylalanine 4-monooxygenase activity Human PAICS IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0009168=Reactome:REACT_1776, GO:0004639=Reactome:REACT_108, GO:0034023=GO_REF:0000002, GO:0004638=Reactome:REACT_589, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_589, GO:0042802=PMID:21988832, GO:0006144=Reactome:REACT_522, GO:0009113=PMID:2253271, GO:0006189=GO_REF:0000041} P22234 Multifunctional protein ADE2 protein 20130415 {GO:0005515=IPI, GO:0009168=TAS, GO:0004639=TAS, GO:0034023=IEA, GO:0004638=TAS, GO:0055086=TAS, GO:0044281=TAS, GO:0005524=IEA, GO:0005829=TAS, GO:0042802=IPI, GO:0006144=TAS, GO:0009113=TAS, GO:0006189=IEA} 'de novo' IMP biosynthetic process, nucleobase-containing small molecule metabolic process, purine nucleobase biosynthetic process, purine nucleobase metabolic process, purine ribonucleoside monophosphate biosynthetic process, small molecule metabolic process cytosol 5-(carboxyamino)imidazole ribonucleotide mutase activity, ATP binding, identical protein binding, phosphoribosylaminoimidazole carboxylase activity, phosphoribosylaminoimidazolesuccinocarboxamide synthase activity, protein binding Human UniProtKB:P22234 PAIP1 GOC UniProtKB {GO:0005515=PMID:11997512, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=GO_REF:0000002, GO:0045727=PMID:9548260, GO:0008494=PMID:9548260, GO:0003677=GO_REF:0000002, GO:0006413=PMID:9548260, GO:0005829=Reactome:REACT_20662, GO:0005737=PMID:9548260, GO:0048255=PMID:11997512, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639} Q9H074 Polyadenylate-binding protein-interacting protein 1 protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=IEA, GO:0045727=IDA, GO:0008494=IDA, GO:0003677=IEA, GO:0006413=TAS, GO:0005829=TAS, GO:0005737=TAS, GO:0048255=TAS, GO:0000289=TAS, GO:0000288=TAS} RNA metabolic process, gene expression, mRNA metabolic process, mRNA stabilization, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA poly(A) tail shortening, positive regulation of translation, translational initiation cytoplasm, cytosol DNA binding, RNA binding, protein binding, translation activator activity Human PAIP2 LIFEdb UniProtKB {GO:0005515=PMID:11172725, GO:0005737=GO_REF:0000054, GO:0045947=PMID:11172725, GO:0030371=PMID:11172725} Q9BPZ3 Polyadenylate-binding protein-interacting protein 2 protein 20100607 {GO:0005515=IPI, GO:0005737=IDA, GO:0045947=IDA, GO:0030371=IDA} negative regulation of translational initiation cytoplasm protein binding, translation repressor activity Human PAIP2B HGNC UniProtKB {GO:0005515=PMID:16804161, GO:0005737=PMID:16804161, GO:0045947=PMID:16804161, GO:0000900=PMID:16804161} Q9ULR5 Polyadenylate-binding protein-interacting protein 2B protein 20070716 {GO:0005515=IPI, GO:0005737=IC, GO:0045947=IDA, GO:0000900=IDA} negative regulation of translational initiation cytoplasm protein binding, translation repressor activity, nucleic acid binding Human PAK1 HPA UniProtKB {GO:0005515=PMID:23455922, GO:0050852=Reactome:REACT_12526, GO:0030424=GO_REF:0000024, GO:0030018=GO_REF:0000024, GO:0005886=GO_REF:0000052, GO:0031295=Reactome:REACT_19344, GO:0005518=PMID:12189148, GO:0060244=PMID:12912914, GO:0006887=GO_REF:0000037, GO:0030425=GO_REF:0000024, GO:0042802=PMID:20936779, GO:0005829=Reactome:REACT_160233, GO:0030426=GO_REF:0000019, GO:0033138=PMID:19667065, GO:0005737=GO_REF:0000052, GO:0046777=PMID:8805275, GO:0014704=GO_REF:0000024, GO:0007411=Reactome:REACT_18266, GO:0005911=PMID:12912914, GO:0000165=PMID:8805275, GO:0007528=GO_REF:0000019, GO:0032956=GO_REF:0000019, GO:0043507=PMID:8805275, GO:0001666=GO_REF:0000019, GO:0031965=GO_REF:0000024, GO:0032869=GO_REF:0000019, GO:0005794=GO_REF:0000052, GO:0031532=PMID:16278681, GO:0019901=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0033554=GO_REF:0000019, GO:0001726=PMID:12912914, GO:0005524=GO_REF:0000037, GO:0016358=GO_REF:0000019, GO:0043234=PMID:11864573, GO:0031941=PMID:9395435, GO:0004672=PMID:9852149, GO:0004674=Reactome:REACT_19221, GO:0045087=Reactome:REACT_6802, GO:0048812=GO_REF:0000024, GO:0051496=PMID:11864573, GO:0042060=PMID:12912914, GO:0043113=GO_REF:0000019, GO:0033148=PMID:16278681, GO:0006468=PMID:9852149, GO:0048754=PMID:20457839, GO:0038096=Reactome:REACT_160123, GO:0005925=GO_REF:0000039} Q13153 Serine/threonine-protein kinase PAK 1 protein 20101115 {GO:0005515=IPI, GO:0050852=TAS, GO:0030424=ISS, GO:0030018=ISS, GO:0005886=IDA, GO:0031295=TAS, GO:0005518=IPI, GO:0060244=IMP, GO:0006887=IEA, GO:0030425=ISS, GO:0042802=IPI, GO:0005829=TAS, GO:0030426=IEA, GO:0033138=IDA, GO:0005737=IDA, GO:0046777=IDA, GO:0014704=ISS, GO:0007411=TAS, GO:0005911=IDA, GO:0000165=IDA, GO:0007528=IEA, GO:0032956=IEA, GO:0043507=IMP, GO:0001666=IEA, GO:0031965=ISS, GO:0032869=IEA, GO:0005794=IDA, GO:0031532=IMP, GO:0019901=IEA, GO:0006915=IEA, GO:0033554=IEA, GO:0001726=IDA, GO:0005524=IEA, GO:0016358=IEA, GO:0043234=IDA, GO:0031941=NAS, GO:0004672=IDA, GO:0004674=TAS, GO:0045087=TAS, GO:0048812=ISS, GO:0051496=IMP, GO:0042060=IMP, GO:0043113=IEA, GO:0033148=IDA, GO:0006468=IDA, GO:0048754=IMP, GO:0038096=TAS, GO:0005925=IEA} Fc-gamma receptor signaling pathway involved in phagocytosis, MAPK cascade, T cell costimulation, T cell receptor signaling pathway, actin cytoskeleton reorganization, apoptotic process, axon guidance, branching morphogenesis of an epithelial tube, cellular response to insulin stimulus, cellular response to stress, dendrite development, exocytosis, innate immune response, negative regulation of cell proliferation involved in contact inhibition, neuromuscular junction development, neuron projection morphogenesis, positive regulation of JUN kinase activity, positive regulation of intracellular estrogen receptor signaling pathway, positive regulation of peptidyl-serine phosphorylation, positive regulation of stress fiber assembly, protein autophosphorylation, protein phosphorylation, receptor clustering, regulation of actin cytoskeleton organization, response to hypoxia, wound healing Golgi apparatus, Z disc, axon, cell-cell junction, cytoplasm, cytosol, dendrite, filamentous actin, focal adhesion, growth cone, intercalated disc, nuclear membrane, plasma membrane, protein complex, ruffle ATP binding, collagen binding, identical protein binding, protein binding, protein kinase activity, protein kinase binding, protein serine/threonine kinase activity Human PAK1IP1 HPA UniProtKB {GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0009968=GO_REF:0000037} Q9NWT1 p21-activated protein kinase-interacting protein 1 protein 20101115 {GO:0005886=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0009968=IEA} negative regulation of signal transduction nucleolus, nucleus, plasma membrane Human PAK2 GOC UniProtKB {GO:0005515=PMID:19240112, GO:0050852=Reactome:REACT_12526, GO:0048471=GO_REF:0000039, GO:0005886=Reactome:REACT_11221, GO:0061098=PMID:11121037, GO:0031295=Reactome:REACT_19344, GO:0050731=PMID:11121037, GO:0005634=GO_REF:0000039, GO:0006921=Reactome:REACT_995, GO:0042802=PMID:21555521, GO:0005829=Reactome:REACT_20657, GO:0030296=PMID:11121037, GO:0046777=PMID:11805089, GO:0018105=PMID:11121037, GO:0007411=Reactome:REACT_18266, GO:0016032=Reactome:REACT_6185, GO:0019901=PMID:11121037, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0005524=GO_REF:0000037, GO:0050690=Reactome:REACT_11068, GO:0007165=PMID:7744004, GO:0004672=PMID:10748018, GO:0004674=PMID:11121037, GO:0019048=GO_REF:0000037, GO:0006468=PMID:11805089, GO:0006469=PMID:10748018, GO:0040008=GO_REF:0000037} Q13177 Serine/threonine-protein kinase PAK 2 protein 20130413 {GO:0005515=IPI, GO:0050852=TAS, GO:0048471=IEA, GO:0005886=TAS, GO:0061098=IDA, GO:0031295=TAS, GO:0050731=IDA, GO:0005634=IEA, GO:0006921=TAS, GO:0042802=IPI, GO:0005829=TAS, GO:0030296=IDA, GO:0046777=IDA, GO:0018105=IDA, GO:0007411=TAS, GO:0016032=TAS, GO:0019901=IPI, GO:0006915=TAS, GO:0042981=TAS, GO:0005524=IEA, GO:0050690=TAS, GO:0007165=TAS, GO:0004672=TAS, GO:0004674=IDA, GO:0019048=IEA, GO:0006468=IDA, GO:0006469=TAS, GO:0040008=IEA} T cell costimulation, T cell receptor signaling pathway, apoptotic process, axon guidance, cellular component disassembly involved in execution phase of apoptosis, negative regulation of protein kinase activity, peptidyl-serine phosphorylation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of protein tyrosine kinase activity, protein autophosphorylation, protein phosphorylation, regulation of apoptotic process, regulation of defense response to virus by virus, regulation of growth, signal transduction, viral reproduction, virus-host interaction cytosol, nucleus, perinuclear region of cytoplasm, plasma membrane ATP binding, identical protein binding, protein binding, protein kinase activity, protein kinase binding, protein serine/threonine kinase activity, protein tyrosine kinase activator activity Human PAK3 GOC UniProtKB {GO:0005515=PMID:11862216, GO:0017124=GO_REF:0000037, GO:0007409=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0016358=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0000187=PMID:21177870, GO:0005737=GO_REF:0000039, GO:0004672=GO_REF:0000019, GO:0030833=PMID:21177870, GO:0050808=PMID:19036346, GO:0000165=PMID:21177870, GO:0004674=GO_REF:0000037, GO:0017048=GO_REF:0000019, GO:0060997=PMID:19036346, GO:0004708=PMID:21177870} O75914 Serine/threonine-protein kinase PAK 3 protein 20130413 {GO:0005515=IPI, GO:0017124=IEA, GO:0007409=ISS, GO:0005524=IEA, GO:0016358=ISS, GO:0046872=IEA, GO:0000187=IDA, GO:0005737=IEA, GO:0004672=IEA, GO:0030833=IDA, GO:0050808=TAS, GO:0000165=IDA, GO:0004674=IEA, GO:0017048=IEA, GO:0060997=TAS, GO:0004708=IDA} MAPK cascade, activation of MAPK activity, axonogenesis, dendrite development, dendritic spine morphogenesis, regulation of actin filament polymerization, synapse organization cytoplasm ATP binding, MAP kinase kinase activity, Rho GTPase binding, SH3 domain binding, metal ion binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human PAK4 PINC UniProtKB {GO:0007165=PMID:20070256, GO:0007049=GO_REF:0000037, GO:0005794=PMID:9822598, GO:0004672=PMID:9822598, GO:0016477=PMID:20070256, GO:0008283=PMID:20070256, GO:0004674=GO_REF:0000037, GO:0007010=PMID:20070256, GO:0006928=PMID:9822598, GO:0016049=PMID:20070256, GO:0006915=PMID:20070256, GO:0005524=GO_REF:0000037} O96013 Serine/threonine-protein kinase PAK 4 protein 20040811 {GO:0007165=TAS, GO:0007049=IEA, GO:0005794=TAS, GO:0004672=NAS, GO:0016477=TAS, GO:0008283=TAS, GO:0004674=IEA, GO:0007010=TAS, GO:0006928=TAS, GO:0016049=TAS, GO:0006915=TAS, GO:0005524=IEA} apoptotic process, cell cycle, cell growth, cell migration, cell proliferation, cellular component movement, cytoskeleton organization, signal transduction Golgi apparatus ATP binding, protein kinase activity, protein serine/threonine kinase activity Human PAK6 UniProtKB UniProtKB {GO:0006355=PMID:20070256, GO:0005737=GO_REF:0000039, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000037, GO:0007010=PMID:20070256, GO:0006915=PMID:20070256, GO:0005634=GO_REF:0000039, GO:0005524=GO_REF:0000037} Q9NQU5 Serine/threonine-protein kinase PAK 6 protein 20110912 {GO:0006355=TAS, GO:0005737=IEA, GO:0004672=IEA, GO:0004674=IEA, GO:0007010=TAS, GO:0006915=TAS, GO:0005634=IEA, GO:0005524=IEA} apoptotic process, cytoskeleton organization, regulation of transcription, DNA-dependent cytoplasm, nucleus ATP binding, protein kinase activity, protein serine/threonine kinase activity Human PAK7 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0007165=PMID:20070256, GO:0043066=GO_REF:0000019, GO:0016477=PMID:20070256, GO:0008283=PMID:20070256, GO:0004674=GO_REF:0000019, GO:0007010=PMID:20070256, GO:0006915=PMID:20070256, GO:0016049=PMID:20070256, GO:0005634=GO_REF:0000039, GO:0005524=GO_REF:0000037} Q9P286 Serine/threonine-protein kinase PAK 7 protein 20110912 {GO:0005739=IEA, GO:0007165=TAS, GO:0043066=IEA, GO:0016477=TAS, GO:0008283=TAS, GO:0004674=IEA, GO:0007010=TAS, GO:0006915=TAS, GO:0016049=TAS, GO:0005634=IEA, GO:0005524=IEA} apoptotic process, cell growth, cell migration, cell proliferation, cytoskeleton organization, negative regulation of apoptotic process, signal transduction mitochondrion, nucleus ATP binding, protein serine/threonine kinase activity Human PALB2 Reactome UniProtKB {GO:0005515=PMID:19423707, GO:0043066=GO_REF:0000019, GO:0006281=Reactome:REACT_216, GO:0000724=PMID:19423707, GO:0001756=GO_REF:0000019, GO:0001833=GO_REF:0000019, GO:0009887=GO_REF:0000019, GO:0005654=Reactome:REACT_21405, GO:0007498=GO_REF:0000019, GO:0003677=PMID:20871616, GO:0036342=GO_REF:0000019} Q86YC2 Partner and localizer of BRCA2 protein 20130213 {GO:0005515=IPI, GO:0043066=IEA, GO:0006281=TAS, GO:0000724=IDA, GO:0001756=IEA, GO:0001833=IEA, GO:0009887=IEA, GO:0005654=TAS, GO:0007498=IEA, GO:0003677=IDA, GO:0036342=IEA} DNA repair, double-strand break repair via homologous recombination, inner cell mass cell proliferation, mesoderm development, negative regulation of apoptotic process, organ morphogenesis, post-anal tail morphogenesis, somitogenesis nucleoplasm DNA binding, protein binding Human PALLD HGNC UniProtKB {GO:0005515=PMID:11598191, GO:0051371=PMID:16125169, GO:0030018=GO_REF:0000039, GO:0005884=PMID:11598191, GO:0007010=PMID:11598191, GO:0005634=PMID:11598191, GO:0003779=GO_REF:0000037, GO:0005925=GO_REF:0000039, GO:0001726=GO_REF:0000039, GO:0030027=GO_REF:0000039} Q8WX93 Palladin protein 20051116 {GO:0005515=IPI, GO:0051371=TAS, GO:0030018=IEA, GO:0005884=IDA, GO:0007010=NAS, GO:0005634=IDA, GO:0003779=IEA, GO:0005925=IEA, GO:0001726=IEA, GO:0030027=IEA} cytoskeleton organization Z disc, actin filament, focal adhesion, lamellipodium, nucleus, ruffle actin binding, muscle alpha-actinin binding, protein binding Human PALM PINC UniProtKB {GO:0005515=PMID:16386234, GO:0060160=PMID:16386234, GO:0030424=GO_REF:0000039, GO:0005886=PMID:16386234, GO:0008360=GO_REF:0000019, GO:0072661=GO_REF:0000019, GO:0031527=PMID:14978216, GO:0006928=PMID:9813098, GO:0051491=PMID:14978216, GO:0007194=PMID:16386234, GO:0016327=GO_REF:0000039, GO:0060074=GO_REF:0000019, GO:0016323=GO_REF:0000039, GO:0071257=GO_REF:0000019, GO:0032590=GO_REF:0000019, GO:0032591=GO_REF:0000019, GO:0005887=PMID:9813098, GO:0007010=GO_REF:0000019, GO:0016023=PMID:9813098, GO:0060999=GO_REF:0000019, GO:0031750=GO_REF:0000019} O75781 Paralemmin-1 protein 20030904 {GO:0005515=IPI, GO:0060160=IDA, GO:0030424=IEA, GO:0005886=IDA, GO:0008360=IEA, GO:0072661=IEA, GO:0031527=IDA, GO:0006928=TAS, GO:0051491=IDA, GO:0007194=IDA, GO:0016327=IEA, GO:0060074=IEA, GO:0016323=IEA, GO:0071257=IEA, GO:0032590=IEA, GO:0032591=IEA, GO:0005887=TAS, GO:0007010=IEA, GO:0016023=TAS, GO:0060999=IEA, GO:0031750=IEA} cellular component movement, cellular response to electrical stimulus, cytoskeleton organization, negative regulation of adenylate cyclase activity, negative regulation of dopamine receptor signaling pathway, positive regulation of dendritic spine development, positive regulation of filopodium assembly, protein targeting to plasma membrane, regulation of cell shape, synapse maturation apicolateral plasma membrane, axon, basolateral plasma membrane, cytoplasmic membrane-bounded vesicle, dendrite membrane, dendritic spine membrane, filopodium membrane, integral to plasma membrane, plasma membrane D3 dopamine receptor binding, protein binding Human PALM2 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0008360=GO_REF:0000002} Q8IXS6 Paralemmin-2 protein 20130413 {GO:0005886=IEA, GO:0016020=IEA, GO:0008360=IEA} regulation of cell shape membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 PALMD UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0043197=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0008360=GO_REF:0000002} Q9NP74 Palmdelphin protein 20130413 {GO:0005737=IEA, GO:0043197=IEA, GO:0016020=IEA, GO:0008360=IEA} regulation of cell shape cytoplasm, dendritic spine, membrane Human UniProtKB-SubCell:SL-0284 PAM PINC UniProtKB {GO:0005515=PMID:9837933, GO:0005802=GO_REF:0000019, GO:0043005=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0001676=GO_REF:0000019, GO:0018032=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0004598=GO_REF:0000003, GO:0007507=GO_REF:0000019, GO:0032956=GO_REF:0000019, GO:0042476=GO_REF:0000019, GO:0043204=GO_REF:0000019, GO:0001519=GO_REF:0000019, GO:0022602=GO_REF:0000019, GO:0051260=GO_REF:0000019, GO:0030141=PMID:7999037, GO:0032355=GO_REF:0000019, GO:0009268=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0031418=GO_REF:0000037, GO:0006357=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0019901=GO_REF:0000019, GO:0005507=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0060135=GO_REF:0000019, GO:0005509=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0051384=GO_REF:0000019, GO:0007417=GO_REF:0000019, GO:0004504=PMID:7999037, GO:0016020=GO_REF:0000002, GO:0050708=GO_REF:0000019, GO:0060173=GO_REF:0000019, GO:0008270=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0009404=GO_REF:0000019, GO:0046688=GO_REF:0000019, GO:0006464=PMID:2357221, GO:0006518=PMID:7999037, GO:0030667=GO_REF:0000019} P19021 Peptidyl-glycine alpha-amidating monooxygenase protein 20030904 {GO:0005515=IPI, GO:0005802=IEA, GO:0043005=IEA, GO:0048471=IEA, GO:0001676=IEA, GO:0018032=IEA, GO:0005886=IEA, GO:0004598=IEA, GO:0007507=IEA, GO:0032956=IEA, GO:0042476=IEA, GO:0043204=IEA, GO:0001519=IEA, GO:0022602=IEA, GO:0051260=IEA, GO:0030141=NAS, GO:0032355=IEA, GO:0009268=IEA, GO:0001666=IEA, GO:0031418=IEA, GO:0006357=IEA, GO:0009986=IEA, GO:0019901=IEA, GO:0005507=IEA, GO:0042493=IEA, GO:0060135=IEA, GO:0005509=IEA, GO:0005576=IEA, GO:0051384=IEA, GO:0007417=IEA, GO:0004504=NAS, GO:0016020=IEA, GO:0050708=IEA, GO:0060173=IEA, GO:0008270=IEA, GO:0016021=IEA, GO:0009404=IEA, GO:0046688=IEA, GO:0006464=TAS, GO:0006518=NAS, GO:0030667=IEA} cellular protein modification process, central nervous system development, heart development, limb development, long-chain fatty acid metabolic process, maternal process involved in female pregnancy, odontogenesis, ovulation cycle process, peptide amidation, peptide metabolic process, protein amidation, protein homooligomerization, regulation of actin cytoskeleton organization, regulation of protein secretion, regulation of transcription from RNA polymerase II promoter, response to copper ion, response to drug, response to estradiol stimulus, response to glucocorticoid stimulus, response to hypoxia, response to pH, toxin metabolic process cell surface, extracellular region, integral to membrane, membrane, neuron projection, perikaryon, perinuclear region of cytoplasm, plasma membrane, secretory granule, secretory granule membrane, trans-Golgi network L-ascorbic acid binding, calcium ion binding, copper ion binding, peptidylamidoglycolate lyase activity, peptidylglycine monooxygenase activity, protein binding, protein kinase binding, zinc ion binding Human PAM16 Reactome UniProtKB {GO:0005744=GO_REF:0000002, GO:0006626=Reactome:REACT_118595, GO:0030150=GO_REF:0000002, GO:0044267=Reactome:REACT_17015} Q9Y3D7 Mitochondrial import inner membrane translocase subunit TIM16 protein 20110427 {GO:0005744=IEA, GO:0006626=TAS, GO:0030150=IEA, GO:0044267=TAS} cellular protein metabolic process, protein import into mitochondrial matrix, protein targeting to mitochondrion mitochondrial inner membrane presequence translocase complex Human PAN2 Reactome UniProtKB {GO:0006511=GO_REF:0000002, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002, GO:0005829=Reactome:REACT_20606, GO:0004535=Reactome:REACT_20606, GO:0000184=GO_REF:0000037, GO:0000932=GO_REF:0000019, GO:0004221=GO_REF:0000002, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639} Q504Q3 PAB-dependent poly(A)-specific ribonuclease subunit 2 protein 20090724 {GO:0006511=IEA, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0005634=IEA, GO:0003676=IEA, GO:0005829=TAS, GO:0004535=TAS, GO:0000184=IEA, GO:0000932=IEA, GO:0004221=IEA, GO:0000289=TAS, GO:0000288=TAS} RNA metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, nuclear-transcribed mRNA poly(A) tail shortening, ubiquitin-dependent protein catabolic process cytoplasmic mRNA processing body, cytosol, nucleus nucleic acid binding, poly(A)-specific ribonuclease activity, ubiquitin thiolesterase activity Human PAN3 HPA UniProtKB {GO:0005515=PMID:21981923, GO:0010467=Reactome:REACT_71, GO:0005813=GO_REF:0000052, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0000290=GO_REF:0000019, GO:0006605=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0005829=Reactome:REACT_20606, GO:0004672=GO_REF:0000002, GO:0000184=GO_REF:0000037, GO:0010606=GO_REF:0000019, GO:0000932=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639} Q58A45 PAB-dependent poly(A)-specific ribonuclease subunit 3 protein 20101115 {GO:0005515=IPI, GO:0010467=TAS, GO:0005813=IDA, GO:0016070=TAS, GO:0016071=TAS, GO:0000290=IEA, GO:0006605=IEA, GO:0003676=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0004672=IEA, GO:0000184=IEA, GO:0010606=IEA, GO:0000932=IEA, GO:0008270=IEA, GO:0000289=TAS, GO:0000288=TAS} RNA metabolic process, deadenylation-dependent decapping of nuclear-transcribed mRNA, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, nuclear-transcribed mRNA poly(A) tail shortening, positive regulation of cytoplasmic mRNA processing body assembly, protein targeting centrosome, cytoplasmic mRNA processing body, cytosol ATP binding, nucleic acid binding, protein binding, protein kinase activity, zinc ion binding Human PANK1 Reactome UniProtKB {GO:0004594=GO_REF:0000003, GO:0015939=Reactome:REACT_11172, GO:0006766=Reactome:REACT_11193, GO:0006767=Reactome:REACT_11238, GO:0009108=Reactome:REACT_11218, GO:0015937=GO_REF:0000041, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_11129, GO:0071944=GO_REF:0000019} Q8TE04 Pantothenate kinase 1 protein 20130301 {GO:0004594=IEA, GO:0015939=TAS, GO:0006766=TAS, GO:0006767=TAS, GO:0009108=TAS, GO:0015937=IEA, GO:0044281=TAS, GO:0005524=IEA, GO:0005829=TAS, GO:0071944=IEA} coenzyme A biosynthetic process, coenzyme biosynthetic process, pantothenate metabolic process, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cell periphery, cytosol ATP binding, pantothenate kinase activity Human PANK2 Reactome UniProtKB {GO:0004594=GO_REF:0000003, GO:0005758=Reactome:REACT_11197, GO:0008219=GO_REF:0000037, GO:0015939=Reactome:REACT_11172, GO:0006766=Reactome:REACT_11193, GO:0006767=Reactome:REACT_11238, GO:0009108=Reactome:REACT_11218, GO:0015937=GO_REF:0000041, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037} Q9BZ23 Pantothenate kinase 2, mitochondrial protein 20130301 {GO:0004594=IEA, GO:0005758=TAS, GO:0008219=IEA, GO:0015939=TAS, GO:0006766=TAS, GO:0006767=TAS, GO:0009108=TAS, GO:0015937=IEA, GO:0044281=TAS, GO:0005524=IEA} cell death, coenzyme A biosynthetic process, coenzyme biosynthetic process, pantothenate metabolic process, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process mitochondrial intermembrane space ATP binding, pantothenate kinase activity Human PANK3 UniPathway UniProtKB {GO:0004594=GO_REF:0000003, GO:0005737=GO_REF:0000039, GO:0015937=GO_REF:0000041, GO:0005524=GO_REF:0000037} Q9H999 Pantothenate kinase 3 protein 20130413 {GO:0004594=IEA, GO:0005737=IEA, GO:0015937=IEA, GO:0005524=IEA} coenzyme A biosynthetic process cytoplasm ATP binding, pantothenate kinase activity Human UniPathway:UPA00241 PANK4 HPA UniProtKB {GO:0004594=GO_REF:0000003, GO:0005737=GO_REF:0000052, GO:0015937=GO_REF:0000041, GO:0005524=GO_REF:0000037} Q9NVE7 Pantothenate kinase 4 protein 20081203 {GO:0004594=IEA, GO:0005737=IDA, GO:0015937=IEA, GO:0005524=IEA} coenzyme A biosynthetic process cytoplasm ATP binding, pantothenate kinase activity Human PANX1 HPA UniProtKB {GO:0005886=GO_REF:0000052, GO:0005783=PMID:16908669, GO:0007268=Reactome:REACT_13685, GO:0055077=PMID:17715132, GO:0002020=GO_REF:0000019, GO:0034214=PMID:17715132, GO:0022840=PMID:16908669, GO:0035872=Reactome:REACT_75913, GO:0051015=GO_REF:0000019, GO:0050717=GO_REF:0000019, GO:0050718=PMID:17036048, GO:0097110=GO_REF:0000019, GO:0033198=GO_REF:0000019, GO:0006816=PMID:16908669, GO:0006812=PMID:17036048, GO:0005262=PMID:16908669, GO:0046982=GO_REF:0000019, GO:0005102=PMID:17036048, GO:0044325=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0032059=PMID:17036048, GO:0002931=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0005789=GO_REF:0000039, GO:0005921=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q96RD7 Pannexin-1 protein 20101115 {GO:0005886=IDA, GO:0005783=IDA, GO:0007268=TAS, GO:0055077=IDA, GO:0002020=IEA, GO:0034214=IDA, GO:0022840=IMP, GO:0035872=TAS, GO:0051015=IEA, GO:0050717=IEA, GO:0050718=IDA, GO:0097110=IEA, GO:0033198=IEA, GO:0006816=IMP, GO:0006812=IDA, GO:0005262=IMP, GO:0046982=IEA, GO:0005102=IPI, GO:0044325=IEA, GO:0043234=IEA, GO:0032059=IDA, GO:0002931=IEA, GO:0045087=TAS, GO:0005789=IEA, GO:0005921=IEA, GO:0016021=IEA} calcium ion transport, cation transport, innate immune response, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, positive regulation of interleukin-1 alpha secretion, positive regulation of interleukin-1 beta secretion, protein hexamerization, response to ATP, response to ischemia, synaptic transmission bleb, endoplasmic reticulum, endoplasmic reticulum membrane, gap junction, integral to membrane, plasma membrane, protein complex actin filament binding, calcium channel activity, gap junction hemi-channel activity, ion channel binding, leak channel activity, protease binding, protein heterodimerization activity, receptor binding, scaffold protein binding Human PANX3 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0007267=GO_REF:0000019, GO:0005921=GO_REF:0000039, GO:0055077=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0034214=GO_REF:0000024, GO:0006811=GO_REF:0000037} Q96QZ0 Pannexin-3 protein 20110125 {GO:0005886=IEA, GO:0007267=IEA, GO:0005921=IEA, GO:0055077=ISS, GO:0016021=IEA, GO:0034214=ISS, GO:0006811=IEA} cell-cell signaling, ion transport, protein hexamerization gap junction, integral to membrane, plasma membrane gap junction hemi-channel activity Human UniProtKB:Q96RD7 PAOX Reactome UniProtKB {GO:0006805=Reactome:REACT_13705, GO:0052901=GO_REF:0000003, GO:0052902=GO_REF:0000003, GO:0005782=Reactome:REACT_2231, GO:0052903=GO_REF:0000003, GO:0052904=Reactome:REACT_2231, GO:0005102=PMID:20178365, GO:0044281=Reactome:REACT_111217, GO:0046592=PMID:16354669, GO:0034641=Reactome:REACT_13, GO:1901307=PMID:16354669, GO:0006596=Reactome:REACT_14805, GO:0052899=GO_REF:0000003, GO:0006595=Reactome:REACT_14820, GO:0009446=PMID:16354669, GO:0046208=PMID:16354669, GO:0046203=PMID:16354669, GO:0009447=PMID:16354669} Q6QHF9 Peroxisomal N(1)-acetyl-spermine/spermidine oxidase protein 20121119 {GO:0006805=TAS, GO:0052901=IEA, GO:0052902=IEA, GO:0005782=TAS, GO:0052903=IEA, GO:0052904=TAS, GO:0005102=IPI, GO:0044281=TAS, GO:0046592=IDA, GO:0034641=TAS, GO:1901307=IDA, GO:0006596=TAS, GO:0052899=IEA, GO:0006595=TAS, GO:0009446=IDA, GO:0046208=IDA, GO:0046203=IDA, GO:0009447=IDA} cellular nitrogen compound metabolic process, polyamine biosynthetic process, polyamine metabolic process, positive regulation of spermidine biosynthetic process, putrescine biosynthetic process, putrescine catabolic process, small molecule metabolic process, spermidine catabolic process, spermine catabolic process, xenobiotic metabolic process peroxisomal matrix N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity, N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity, N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity, polyamine oxidase activity, receptor binding, spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity, spermine:oxygen oxidoreductase (spermidine-forming) activity Human PAPD4 UniProtKB UniProtKB {GO:0006397=GO_REF:0000037, GO:0004652=PMID:15070731, GO:0005737=GO_REF:0000039, GO:0031380=PMID:15070731, GO:0071044=PMID:18172165, GO:0043631=PMID:15070731, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q6PIY7 Poly(A) RNA polymerase GLD2 protein 20091202 {GO:0006397=IEA, GO:0004652=IDA, GO:0005737=IEA, GO:0031380=IC, GO:0071044=IMP, GO:0043631=IDA, GO:0005524=IEA, GO:0046872=IEA} RNA polyadenylation, histone mRNA catabolic process, mRNA processing cytoplasm, nuclear RNA-directed RNA polymerase complex ATP binding, metal ion binding, polynucleotide adenylyltransferase activity Human PAPD5 UniProtKB UniProtKB {GO:0006260=GO_REF:0000037, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000039, GO:0007067=GO_REF:0000037, GO:0003887=GO_REF:0000037, GO:0071044=PMID:18172165, GO:0016779=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0003677=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0051301=GO_REF:0000037} Q8NDF8 PAP-associated domain-containing protein 5 protein 20091202 {GO:0006260=IEA, GO:0003674=ND, GO:0005737=IEA, GO:0007067=IEA, GO:0003887=IEA, GO:0071044=IMP, GO:0016779=IEA, GO:0005634=IEA, GO:0005575=ND, GO:0003677=IEA, GO:0046872=IEA, GO:0051301=IEA} DNA replication, cell division, histone mRNA catabolic process, mitosis cellular_component, cytoplasm, nucleus DNA binding, DNA-directed DNA polymerase activity, metal ion binding, molecular_function, nucleotidyltransferase activity Human PAPD7 UniProtKB UniProtKB {GO:0006260=GO_REF:0000037, GO:0007076=PMID:10066793, GO:0043221=PMID:10066793, GO:0042493=PMID:10066793, GO:0003887=GO_REF:0000003, GO:0007062=PMID:10066793, GO:0005634=PMID:10066793, GO:0003677=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0006302=PMID:10066793, GO:0051301=GO_REF:0000037} Q5XG87 DNA polymerase sigma protein 20060120 {GO:0006260=IEA, GO:0007076=NAS, GO:0043221=TAS, GO:0042493=IDA, GO:0003887=IEA, GO:0007062=TAS, GO:0005634=IDA, GO:0003677=IEA, GO:0046872=IEA, GO:0006302=NAS, GO:0051301=IEA} DNA replication, cell division, double-strand break repair, mitotic chromosome condensation, response to drug, sister chromatid cohesion nucleus DNA binding, DNA-directed DNA polymerase activity, SMC family protein binding, metal ion binding Human PAPOLA HPA UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0006378=GO_REF:0000029, GO:0000287=GO_REF:0000024, GO:0030145=GO_REF:0000024, GO:0006366=Reactome:REACT_1366, GO:0003723=GO_REF:0000029, GO:0031124=Reactome:REACT_1849, GO:0005730=GO_REF:0000052, GO:0043631=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000024, GO:0004652=GO_REF:0000024, GO:0005737=PMID:8302877, GO:0000398=Reactome:REACT_467, GO:0005654=Reactome:REACT_1935} P51003 Poly(A) polymerase alpha protein 20080205 {GO:0008380=TAS, GO:0010467=TAS, GO:0006369=TAS, GO:0006378=NAS, GO:0000287=ISS, GO:0030145=ISS, GO:0006366=TAS, GO:0003723=NAS, GO:0031124=TAS, GO:0005730=IDA, GO:0043631=ISS, GO:0005634=IDA, GO:0005524=ISS, GO:0004652=ISS, GO:0005737=TAS, GO:0000398=TAS, GO:0005654=TAS} RNA polyadenylation, RNA splicing, gene expression, mRNA 3'-end processing, mRNA polyadenylation, mRNA splicing, via spliceosome, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter cytoplasm, nucleolus, nucleoplasm, nucleus ATP binding, RNA binding, magnesium ion binding, manganese ion binding, polynucleotide adenylyltransferase activity NOT Human PAPOLB RefGenome UniProtKB {GO:0006378=GO_REF:0000033, GO:0006369=GO_REF:0000033, GO:0004652=GO_REF:0000033, GO:0005737=GO_REF:0000033, GO:0000398=GO_REF:0000033, GO:0005783=GO_REF:0000019, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000033, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q9NRJ5 Poly(A) polymerase beta protein 20121212 {GO:0006378=IBA, GO:0006369=IBA, GO:0004652=IBA, GO:0005737=IBA, GO:0000398=IBA, GO:0005783=IEA, GO:0003723=IEA, GO:0005634=IBA, GO:0005524=IEA, GO:0046872=IEA} mRNA polyadenylation, mRNA splicing, via spliceosome, termination of RNA polymerase II transcription cytoplasm, endoplasmic reticulum, nucleus ATP binding, RNA binding, metal ion binding, polynucleotide adenylyltransferase activity Human PANTHER:PTN000074206 PAPOLG RefGenome UniProtKB {GO:0006378=GO_REF:0000033, GO:0004652=GO_REF:0000033, GO:0003723=GO_REF:0000037, GO:0043631=GO_REF:0000002, GO:0005634=GO_REF:0000033, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q9BWT3 Poly(A) polymerase gamma protein 20121212 {GO:0006378=IBA, GO:0004652=IBA, GO:0003723=IEA, GO:0043631=IEA, GO:0005634=IBA, GO:0005524=IEA, GO:0046872=IEA} RNA polyadenylation, mRNA polyadenylation nucleus ATP binding, RNA binding, metal ion binding, polynucleotide adenylyltransferase activity Human PANTHER:PTN000074206 PAPPA Reactome UniProtKB {GO:0007565=PMID:10077652, GO:0004175=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0005576=Reactome:REACT_15447, GO:0008270=PMID:10077652, GO:0051384=GO_REF:0000019, GO:0044267=Reactome:REACT_17015, GO:0005615=GO_REF:0000019, GO:0008237=PMID:10077652, GO:0032354=GO_REF:0000019, GO:0030154=GO_REF:0000002} Q13219 Pappalysin-1 protein 20130301 {GO:0007565=NAS, GO:0004175=IEA, GO:0016020=IEA, GO:0006508=IEA, GO:0005576=TAS, GO:0008270=NAS, GO:0051384=IEA, GO:0044267=TAS, GO:0005615=IEA, GO:0008237=IDA, GO:0032354=IEA, GO:0030154=IEA} cell differentiation, cellular protein metabolic process, female pregnancy, proteolysis, response to follicle-stimulating hormone stimulus, response to glucocorticoid stimulus extracellular region, extracellular space, membrane endopeptidase activity, metallopeptidase activity, zinc ion binding Human PAPPA2 Reactome UniProtKB {GO:0005622=PMID:11264294, GO:0016020=GO_REF:0000002, GO:0006508=PMID:11264294, GO:0005576=Reactome:REACT_15304, GO:0008270=PMID:11264294, GO:0044267=Reactome:REACT_17015, GO:0001558=PMID:11264294, GO:0008237=PMID:11264294, GO:0030154=GO_REF:0000002} Q9BXP8 Pappalysin-2 protein 20130301 {GO:0005622=NAS, GO:0016020=IEA, GO:0006508=IDA, GO:0005576=TAS, GO:0008270=NAS, GO:0044267=TAS, GO:0001558=NAS, GO:0008237=IDA, GO:0030154=IEA} cell differentiation, cellular protein metabolic process, proteolysis, regulation of cell growth extracellular region, intracellular, membrane metallopeptidase activity, zinc ion binding Human PAPSS1 Reactome UniProtKB {GO:0001501=PMID:9771708, GO:0004020=GO_REF:0000003, GO:0006805=Reactome:REACT_13433, GO:0050427=Reactome:REACT_6913, GO:0050428=Reactome:REACT_6840, GO:0016779=GO_REF:0000024, GO:0004781=GO_REF:0000024, GO:0000103=GO_REF:0000041, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_6792} O43252 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 protein 20130301 {GO:0001501=TAS, GO:0004020=IEA, GO:0006805=TAS, GO:0050427=TAS, GO:0050428=TAS, GO:0016779=ISS, GO:0004781=ISS, GO:0000103=IEA, GO:0044281=TAS, GO:0005524=IEA, GO:0005829=TAS} 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process, 3'-phosphoadenosine 5'-phosphosulfate metabolic process, skeletal system development, small molecule metabolic process, sulfate assimilation, xenobiotic metabolic process cytosol ATP binding, adenylylsulfate kinase activity, nucleotidyltransferase activity, sulfate adenylyltransferase (ATP) activity Human PAPSS2 Reactome UniProtKB {GO:0006805=Reactome:REACT_13433, GO:0050427=Reactome:REACT_6913, GO:0050428=Reactome:REACT_6840, GO:0016779=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_6792, GO:0060348=GO_REF:0000019, GO:0004020=GO_REF:0000003, GO:0001501=PMID:9771708, GO:0007596=GO_REF:0000019, GO:0000103=GO_REF:0000041, GO:0004781=GO_REF:0000024} O95340 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 protein 20130301 {GO:0006805=TAS, GO:0050427=TAS, GO:0050428=TAS, GO:0016779=ISS, GO:0044281=TAS, GO:0005524=IEA, GO:0005829=TAS, GO:0060348=IEA, GO:0004020=IEA, GO:0001501=TAS, GO:0007596=IEA, GO:0000103=IEA, GO:0004781=ISS} 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process, 3'-phosphoadenosine 5'-phosphosulfate metabolic process, blood coagulation, bone development, skeletal system development, small molecule metabolic process, sulfate assimilation, xenobiotic metabolic process cytosol ATP binding, adenylylsulfate kinase activity, nucleotidyltransferase activity, sulfate adenylyltransferase (ATP) activity Human PAQR3 UniProtKB UniProtKB {GO:0000139=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q6TCH7 Progestin and adipoQ receptor family member 3 protein 20130413 {GO:0000139=IEA, GO:0016021=IEA} Golgi membrane, integral to membrane Human UniProtKB-SubCell:SL-0134 PAQR7 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0048477=GO_REF:0000037, GO:0007275=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005496=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q86WK9 Membrane progestin receptor alpha protein 20130413 {GO:0005886=IEA, GO:0048477=IEA, GO:0007275=IEA, GO:0016021=IEA, GO:0005496=IEA, GO:0030154=IEA} cell differentiation, multicellular organismal development, oogenesis integral to membrane, plasma membrane steroid binding Human UniProtKB-SubCell:SL-0039 PARD3 IntAct UniProtKB {GO:0005515=PMID:17979178, GO:0044319=GO_REF:0000019, GO:0090162=GO_REF:0000024, GO:0030054=Reactome:REACT_121319, GO:0005886=Reactome:REACT_19353, GO:0007409=PMID:14676191, GO:0007205=PMID:11260256, GO:0005829=Reactome:REACT_19353, GO:0051642=GO_REF:0000019, GO:0032970=GO_REF:0000019, GO:0005913=GO_REF:0000019, GO:0070830=Reactome:REACT_19373, GO:0005911=PMID:20332120, GO:0006612=GO_REF:0000024, GO:0005080=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0007179=Reactome:REACT_120726, GO:0005938=GO_REF:0000039, GO:0008356=PMID:10934474, GO:0003383=GO_REF:0000019, GO:0034329=Reactome:REACT_20676, GO:0019903=GO_REF:0000019, GO:0005547=GO_REF:0000024, GO:0005819=GO_REF:0000019, GO:0045177=GO_REF:0000019, GO:0000226=GO_REF:0000019, GO:0005546=GO_REF:0000024, GO:0032266=GO_REF:0000024, GO:0044295=GO_REF:0000019, GO:0045216=Reactome:REACT_19331, GO:0012505=GO_REF:0000039, GO:0007049=GO_REF:0000037, GO:0006461=PMID:10934474, GO:0007163=PMID:14676191, GO:0005923=PMID:22006950, GO:0060341=GO_REF:0000019} Q8TEW0 Partitioning defective 3 homolog protein 20130415 {GO:0005515=IPI, GO:0044319=IEA, GO:0090162=ISS, GO:0030054=TAS, GO:0005886=TAS, GO:0007409=TAS, GO:0007205=TAS, GO:0005829=TAS, GO:0051642=IEA, GO:0032970=IEA, GO:0005913=IEA, GO:0070830=TAS, GO:0005911=IDA, GO:0006612=ISS, GO:0005080=IEA, GO:0043025=IEA, GO:0007179=TAS, GO:0005938=IEA, GO:0008356=TAS, GO:0003383=IEA, GO:0034329=TAS, GO:0019903=IEA, GO:0005547=ISS, GO:0005819=IEA, GO:0045177=IEA, GO:0000226=IEA, GO:0005546=ISS, GO:0032266=ISS, GO:0044295=IEA, GO:0045216=TAS, GO:0012505=IEA, GO:0007049=IEA, GO:0006461=TAS, GO:0007163=TAS, GO:0005923=IDA, GO:0060341=IEA} apical constriction, asymmetric cell division, axonogenesis, cell cycle, cell junction assembly, cell-cell junction organization, centrosome localization, establishment of epithelial cell polarity, establishment or maintenance of cell polarity, microtubule cytoskeleton organization, protein complex assembly, protein kinase C-activating G-protein coupled receptor signaling pathway, protein targeting to membrane, regulation of actin filament-based process, regulation of cellular localization, tight junction assembly, transforming growth factor beta receptor signaling pathway, wound healing, spreading of cells apical part of cell, axonal growth cone, cell cortex, cell junction, cell-cell adherens junction, cell-cell junction, cytosol, endomembrane system, neuronal cell body, plasma membrane, spindle, tight junction phosphatidylinositol-3,4,5-trisphosphate binding, phosphatidylinositol-3-phosphate binding, phosphatidylinositol-4,5-bisphosphate binding, protein binding, protein kinase C binding, protein phosphatase binding Human UniProtKB:Q04917 PARD3B UniProtKB UniProtKB {GO:0007049=GO_REF:0000037, GO:0016020=GO_REF:0000037, GO:0005923=GO_REF:0000039, GO:0012505=GO_REF:0000039, GO:0051301=GO_REF:0000037} Q8TEW8 Partitioning defective 3 homolog B protein 20130413 {GO:0007049=IEA, GO:0016020=IEA, GO:0005923=IEA, GO:0012505=IEA, GO:0051301=IEA} cell cycle, cell division endomembrane system, membrane, tight junction Human UniProtKB-SubCell:SL-0147 PARD6A IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0005886=Reactome:REACT_121150, GO:0034329=Reactome:REACT_20676, GO:0045177=GO_REF:0000019, GO:0005634=GO_REF:0000024, GO:0001726=GO_REF:0000039, GO:0045216=Reactome:REACT_19331, GO:0005829=Reactome:REACT_19353, GO:0045217=GO_REF:0000024, GO:0043234=GO_REF:0000019, GO:0007049=GO_REF:0000037, GO:0030742=GO_REF:0000024, GO:0070830=Reactome:REACT_19373, GO:0005080=GO_REF:0000019, GO:0016032=PMID:9482110, GO:0007179=Reactome:REACT_120726, GO:0017048=GO_REF:0000024, GO:0005923=GO_REF:0000024, GO:0005938=GO_REF:0000019, GO:0008134=PMID:9482110, GO:0051301=GO_REF:0000037} Q9NPB6 Partitioning defective 6 homolog alpha protein 20130415 {GO:0005515=IPI, GO:0005886=TAS, GO:0034329=TAS, GO:0045177=IEA, GO:0005634=ISS, GO:0001726=IEA, GO:0045216=TAS, GO:0005829=TAS, GO:0045217=ISS, GO:0043234=IEA, GO:0007049=IEA, GO:0030742=ISS, GO:0070830=TAS, GO:0005080=IEA, GO:0016032=TAS, GO:0007179=TAS, GO:0017048=ISS, GO:0005923=ISS, GO:0005938=IEA, GO:0008134=TAS, GO:0051301=IEA} cell cycle, cell division, cell junction assembly, cell-cell junction maintenance, cell-cell junction organization, tight junction assembly, transforming growth factor beta receptor signaling pathway, viral reproduction apical part of cell, cell cortex, cytosol, nucleus, plasma membrane, protein complex, ruffle, tight junction GTP-dependent protein binding, Rho GTPase binding, protein binding, protein kinase C binding, transcription factor binding Human UniProtKB:Q05513 PARD6B HPA UniProtKB {GO:0005515=PMID:20936779, GO:0030334=PMID:14676191, GO:0005886=Reactome:REACT_19353, GO:0034329=Reactome:REACT_20676, GO:0045177=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0007409=PMID:14676191, GO:0045216=Reactome:REACT_19331, GO:0005829=Reactome:REACT_19353, GO:0043234=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0007049=GO_REF:0000037, GO:0006461=PMID:12545177, GO:0007163=PMID:14676191, GO:0070830=Reactome:REACT_19373, GO:0007043=PMID:12545177, GO:0005923=PMID:12545177, GO:0005938=GO_REF:0000019, GO:0051301=GO_REF:0000037} Q9BYG5 Partitioning defective 6 homolog beta protein 20081203 {GO:0005515=IPI, GO:0030334=TAS, GO:0005886=TAS, GO:0034329=TAS, GO:0045177=IEA, GO:0005634=IEA, GO:0007409=TAS, GO:0045216=TAS, GO:0005829=TAS, GO:0043234=IEA, GO:0005737=IDA, GO:0007049=IEA, GO:0006461=IDA, GO:0007163=TAS, GO:0070830=TAS, GO:0007043=TAS, GO:0005923=IDA, GO:0005938=IEA, GO:0051301=IEA} axonogenesis, cell cycle, cell division, cell junction assembly, cell-cell junction assembly, cell-cell junction organization, establishment or maintenance of cell polarity, protein complex assembly, regulation of cell migration, tight junction assembly apical part of cell, cell cortex, cytoplasm, cytosol, nucleus, plasma membrane, protein complex, tight junction protein binding Human PARD6G IntAct UniProtKB {GO:0005515=PMID:14676191, GO:0043234=GO_REF:0000019, GO:0007049=GO_REF:0000037, GO:0070830=Reactome:REACT_19373, GO:0005886=Reactome:REACT_19353, GO:0034329=Reactome:REACT_20676, GO:0005923=GO_REF:0000039, GO:0045216=Reactome:REACT_19331, GO:0005829=Reactome:REACT_19353, GO:0051301=GO_REF:0000037} Q9BYG4 Partitioning defective 6 homolog gamma protein 20130415 {GO:0005515=IPI, GO:0043234=IEA, GO:0007049=IEA, GO:0070830=TAS, GO:0005886=TAS, GO:0034329=TAS, GO:0005923=IEA, GO:0045216=TAS, GO:0005829=TAS, GO:0051301=IEA} cell cycle, cell division, cell junction assembly, cell-cell junction organization, tight junction assembly cytosol, plasma membrane, protein complex, tight junction protein binding Human UniProtKB:Q96L34 PARG HPA UniProtKB {GO:0005737=PMID:9925755, GO:0005975=GO_REF:0000002, GO:0005759=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0004649=PMID:15450800, GO:0005634=GO_REF:0000052, GO:0016045=GO_REF:0000019, GO:0006974=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0043231=GO_REF:0000052} Q86W56 Poly(ADP-ribose) glycohydrolase protein 20101115 {GO:0005737=TAS, GO:0005975=IEA, GO:0005759=IEA, GO:0005730=IDA, GO:0004649=IDA, GO:0005634=IDA, GO:0016045=IEA, GO:0006974=IEA, GO:0005829=IEA, GO:0043231=IDA} carbohydrate metabolic process, detection of bacterium, response to DNA damage stimulus cytoplasm, cytosol, intracellular membrane-bounded organelle, mitochondrial matrix, nucleolus, nucleus poly(ADP-ribose) glycohydrolase activity Human PARK2 BHF-UCL UniProtKB {GO:0005515=PMID:15603737, GO:0008219=PMID:21376232, GO:0006511=PMID:21376232, GO:0048471=PMID:17097639, GO:0004842=PMID:16227987, GO:0006513=PMID:20889974, GO:0005783=GO_REF:0000039, GO:0051087=PMID:15603737, GO:0005634=GO_REF:0000039, GO:0005829=PMID:19880420, GO:0005739=PMID:20889974, GO:0043524=PMID:22511790, GO:0005737=PMID:17512523, GO:0070534=PMID:19880420, GO:0090201=PMID:19880420, GO:0042787=PMID:17097639, GO:0032232=PMID:17512523, GO:0060548=PMID:15603737, GO:0019900=PMID:17512523, GO:0043123=PMID:19880420, GO:0031625=PMID:21532592, GO:0000209=PMID:16227987, GO:0005794=PMID:17097639, GO:0019901=PMID:20798600, GO:0000422=PMID:19029340, GO:0016235=PMID:14645198, GO:0030165=PMID:17512523, GO:0007417=PMID:9560156, GO:0051865=PMID:17512523, GO:0070997=PMID:21376232, GO:0070842=PMID:14645198, GO:0001933=PMID:17512523, GO:0010506=PMID:20889974, GO:0008270=GO_REF:0000002, GO:2000377=PMID:18541373, GO:0070936=PMID:21376232} O60260 E3 ubiquitin-protein ligase parkin protein 20100524 {GO:0005515=IPI, GO:0008219=IDA, GO:0006511=IDA, GO:0048471=IDA, GO:0004842=IDA, GO:0006513=IDA, GO:0005783=IEA, GO:0051087=IPI, GO:0005634=IEA, GO:0005829=IDA, GO:0005739=IDA, GO:0043524=IDA, GO:0005737=IDA, GO:0070534=IDA, GO:0090201=IDA, GO:0042787=IDA, GO:0032232=IDA, GO:0060548=IDA, GO:0019900=IPI, GO:0043123=IDA, GO:0031625=IPI, GO:0000209=IDA, GO:0005794=IDA, GO:0019901=IPI, GO:0000422=IMP, GO:0016235=IDA, GO:0030165=IPI, GO:0007417=TAS, GO:0051865=IDA, GO:0070997=IDA, GO:0070842=IMP, GO:0001933=IDA, GO:0010506=IDA, GO:0008270=IEA, GO:2000377=IMP, GO:0070936=IDA} aggresome assembly, cell death, central nervous system development, mitochondrion degradation, negative regulation of actin filament bundle assembly, negative regulation of cell death, negative regulation of neuron apoptotic process, negative regulation of protein phosphorylation, negative regulation of release of cytochrome c from mitochondria, neuron death, positive regulation of I-kappaB kinase/NF-kappaB cascade, protein K48-linked ubiquitination, protein K63-linked ubiquitination, protein autoubiquitination, protein monoubiquitination, protein polyubiquitination, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, regulation of autophagy, regulation of reactive oxygen species metabolic process, ubiquitin-dependent protein catabolic process Golgi apparatus, aggresome, cytoplasm, cytosol, endoplasmic reticulum, mitochondrion, nucleus, perinuclear region of cytoplasm PDZ domain binding, chaperone binding, kinase binding, protein binding, protein kinase binding, ubiquitin protein ligase binding, ubiquitin-protein ligase activity, zinc ion binding Human PARK7 BHF-UCL UniProtKB {GO:0032091=PMID:11477070, GO:0005515=PMID:21785459, GO:0008344=GO_REF:0000019, GO:0008219=GO_REF:0000037, GO:0051899=GO_REF:0000019, GO:0070301=PMID:14749723, GO:0005634=PMID:12446870, GO:0003729=PMID:18626009, GO:0042803=PMID:18711745, GO:0007338=GO_REF:0000037, GO:0005739=PMID:18711745, GO:0051583=GO_REF:0000019, GO:0043523=PMID:20304780, GO:0043524=PMID:22511790, GO:0005737=PMID:12446870, GO:0006954=GO_REF:0000037, GO:0004601=GO_REF:0000024, GO:0006508=GO_REF:0000037, GO:0060548=PMID:14749723, GO:0051920=GO_REF:0000019, GO:0042743=GO_REF:0000019, GO:0060765=PMID:11477070, GO:0006914=GO_REF:0000037, GO:0050821=PMID:17015834, GO:0050727=GO_REF:0000024, GO:0060081=GO_REF:0000019, GO:0008233=PMID:20304780, GO:0007005=GO_REF:0000024, GO:2000277=GO_REF:0000019} Q99497 Protein DJ-1 protein 20120613 {GO:0032091=IDA, GO:0005515=IPI, GO:0008344=IEA, GO:0008219=IEA, GO:0051899=IEA, GO:0070301=IDA, GO:0005634=IDA, GO:0003729=IDA, GO:0042803=IDA, GO:0007338=IEA, GO:0005739=IDA, GO:0051583=IEA, GO:0043523=IDA, GO:0043524=IDA, GO:0005737=IDA, GO:0006954=IEA, GO:0004601=ISS, GO:0006508=IEA, GO:0060548=IDA, GO:0051920=IEA, GO:0042743=IEA, GO:0060765=IDA, GO:0006914=IEA, GO:0050821=IMP, GO:0050727=ISS, GO:0060081=IEA, GO:0008233=IDA, GO:0007005=ISS, GO:2000277=IEA} adult locomotory behavior, autophagy, cell death, cellular response to hydrogen peroxide, dopamine uptake involved in synaptic transmission, hydrogen peroxide metabolic process, inflammatory response, membrane depolarization, membrane hyperpolarization, mitochondrion organization, negative regulation of cell death, negative regulation of neuron apoptotic process, negative regulation of protein binding, positive regulation of oxidative phosphorylation uncoupler activity, protein stabilization, proteolysis, regulation of androgen receptor signaling pathway, regulation of inflammatory response, regulation of neuron apoptotic process, single fertilization cytoplasm, mitochondrion, nucleus mRNA binding, peptidase activity, peroxidase activity, peroxiredoxin activity, protein binding, protein homodimerization activity Human PARL HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0090201=GO_REF:0000019, GO:0004252=GO_REF:0000002, GO:0005743=GO_REF:0000039, GO:0006508=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:2001243=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q9H300 Presenilins-associated rhomboid-like protein, mitochondrial protein 20100326 {GO:0005739=IDA, GO:0090201=IEA, GO:0004252=IEA, GO:0005743=IEA, GO:0006508=IEA, GO:0005634=IEA, GO:2001243=IEA, GO:0016021=IEA} negative regulation of intrinsic apoptotic signaling pathway, negative regulation of release of cytochrome c from mitochondria, proteolysis integral to membrane, mitochondrial inner membrane, mitochondrion, nucleus serine-type endopeptidase activity Human PARN GOC UniProtKB {GO:0005515=PMID:21876179, GO:0010467=Reactome:REACT_71, GO:0090305=PMID:9736620, GO:0016070=Reactome:REACT_21257, GO:0019901=PMID:20932473, GO:0016071=Reactome:REACT_20605, GO:0003723=GO_REF:0000002, GO:0005730=GO_REF:0000039, GO:0005634=PMID:9736620, GO:0007292=PMID:9736620, GO:0006402=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_25257, GO:0004535=Reactome:REACT_20662, GO:0005737=PMID:9736620, GO:0004518=PMID:9736620, GO:0000166=GO_REF:0000002, GO:0000184=PMID:22890540, GO:0009451=PMID:9736620, GO:0003730=PMID:9736620, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639} O95453 Poly(A)-specific ribonuclease PARN protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0090305=TAS, GO:0016070=TAS, GO:0019901=IPI, GO:0016071=TAS, GO:0003723=IEA, GO:0005730=IEA, GO:0005634=TAS, GO:0007292=TAS, GO:0006402=IEA, GO:0003676=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0004535=TAS, GO:0005737=TAS, GO:0004518=TAS, GO:0000166=IEA, GO:0000184=IMP, GO:0009451=TAS, GO:0003730=TAS, GO:0000289=TAS, GO:0000288=TAS} RNA metabolic process, RNA modification, female gamete generation, gene expression, mRNA catabolic process, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, nuclear-transcribed mRNA poly(A) tail shortening, nucleic acid phosphodiester bond hydrolysis cytoplasm, cytosol, nucleolus, nucleus RNA binding, mRNA 3'-UTR binding, metal ion binding, nuclease activity, nucleic acid binding, nucleotide binding, poly(A)-specific ribonuclease activity, protein binding, protein kinase binding Human PARP1 InterPro UniProtKB {GO:0005515=PMID:22863007, GO:0010467=Reactome:REACT_71, GO:0016540=GO_REF:0000019, GO:0006367=Reactome:REACT_12627, GO:0006366=PMID:10944198, GO:0005634=GO_REF:0000052, GO:0005635=PMID:9518481, GO:0003950=PMID:19470756, GO:0006302=PMID:23230272, GO:0006471=PMID:17396150, GO:0051287=GO_REF:0000019, GO:0000723=GO_REF:0000019, GO:0042769=GO_REF:0000019, GO:0007179=Reactome:REACT_6844, GO:0005667=PMID:19303849, GO:0032869=PMID:19303849, GO:0005730=PMID:9518481, GO:0000122=Reactome:REACT_121111, GO:0003677=GO_REF:0000002, GO:0006351=Reactome:REACT_121061, GO:0070212=PMID:19470756, GO:0006281=PMID:17396150, GO:0047485=PMID:16107709, GO:0006284=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_121212, GO:0040009=GO_REF:0000019, GO:0008134=PMID:19303849} Q5VX85 "Poly ""ADP-ribose"" polymerase 1" protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0016540=IEA, GO:0006367=TAS, GO:0006366=TAS, GO:0005634=IDA, GO:0005635=IDA, GO:0003950=IDA, GO:0006302=IMP, GO:0006471=IDA, GO:0051287=IEA, GO:0000723=IEA, GO:0042769=IEA, GO:0007179=TAS, GO:0005667=IDA, GO:0032869=IDA, GO:0005730=IDA, GO:0000122=TAS, GO:0003677=IEA, GO:0006351=TAS, GO:0070212=IDA, GO:0006281=TAS, GO:0047485=IPI, GO:0006284=IEA, GO:0008270=IEA, GO:0005654=TAS, GO:0040009=IEA, GO:0008134=IPI} DNA damage response, detection of DNA damage, DNA repair, base-excision repair, cellular response to insulin stimulus, double-strand break repair, gene expression, negative regulation of transcription from RNA polymerase II promoter, protein ADP-ribosylation, protein autoprocessing, protein poly-ADP-ribosylation, regulation of growth rate, telomere maintenance, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway nuclear envelope, nucleolus, nucleoplasm, nucleus, transcription factor complex DNA binding, NAD binding, NAD+ ADP-ribosyltransferase activity, protein N-terminus binding, protein binding, transcription factor binding, zinc ion binding Human InterPro:IPR001510 PARP10 HPA UniProtKB {GO:0005515=PMID:15674325, GO:0070212=PMID:15674325, GO:0005737=PMID:15674325, GO:0005794=GO_REF:0000052, GO:0000166=GO_REF:0000002, GO:0010847=PMID:15674325, GO:0048147=PMID:15674325, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003950=GO_REF:0000003} Q53GL7 "Poly ""ADP-ribose"" polymerase 10" protein 20101115 {GO:0005515=IPI, GO:0070212=IDA, GO:0005737=IDA, GO:0005794=IDA, GO:0000166=IEA, GO:0010847=IDA, GO:0048147=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0003950=IEA} negative regulation of fibroblast proliferation, protein poly-ADP-ribosylation, regulation of chromatin assembly Golgi apparatus, cytoplasm, nucleolus, nucleus NAD+ ADP-ribosyltransferase activity, nucleotide binding, protein binding Human PARP11 UniProtKB UniProtKB {GO:0003950=GO_REF:0000003} Q9NR21 "Poly ""ADP-ribose"" polymerase 11" protein 20130413 {GO:0003950=IEA} NAD+ ADP-ribosyltransferase activity Human EC:2.4.2.30 PARP12 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003950=GO_REF:0000003} Q9H0J9 "Poly ""ADP-ribose"" polymerase 12" protein 20130413 {GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003950=IEA} nucleus NAD+ ADP-ribosyltransferase activity, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 PARP14 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0005886=GO_REF:0000052, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037, GO:0003950=GO_REF:0000003} Q460N5 "Poly ""ADP-ribose"" polymerase 14" protein 20081203 {GO:0005737=IDA, GO:0006355=IEA, GO:0005886=IDA, GO:0005634=IEA, GO:0006351=IEA, GO:0003950=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus, plasma membrane NAD+ ADP-ribosyltransferase activity Human PARP15 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037, GO:0003950=GO_REF:0000003} Q460N3 "Poly ""ADP-ribose"" polymerase 15" protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0006351=IEA, GO:0003950=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus NAD+ ADP-ribosyltransferase activity Human UniProtKB-SubCell:SL-0191 PARP16 UniProtKB UniProtKB {GO:0006986=GO_REF:0000037, GO:0031965=GO_REF:0000039, GO:0003956=GO_REF:0000003, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0003950=GO_REF:0000002} Q8N5Y8 "Mono ""ADP-ribose"" polymerase PARP16" protein 20130413 {GO:0006986=IEA, GO:0031965=IEA, GO:0003956=IEA, GO:0005789=IEA, GO:0016021=IEA, GO:0003950=IEA} response to unfolded protein endoplasmic reticulum membrane, integral to membrane, nuclear membrane NAD(P)+-protein-arginine ADP-ribosyltransferase activity, NAD+ ADP-ribosyltransferase activity Human UniProtKB-SubCell:SL-0182 PARP2 MGI UniProtKB {GO:0006471=GO_REF:0000002, GO:0006281=PMID:7260241, GO:0006284=GO_REF:0000019, GO:0005730=PMID:15615785, GO:0005654=PMID:15615785, GO:0003677=GO_REF:0000037, GO:0003950=GO_REF:0000003} Q9UGN5 "Poly ""ADP-ribose"" polymerase 2" protein 20081205 {GO:0006471=IEA, GO:0006281=TAS, GO:0006284=IEA, GO:0005730=IDA, GO:0005654=IDA, GO:0003677=IEA, GO:0003950=IEA} DNA repair, base-excision repair, protein ADP-ribosylation nucleolus, nucleoplasm DNA binding, NAD+ ADP-ribosyltransferase activity Human PARP3 PINC UniProtKB {GO:0006471=GO_REF:0000002, GO:0006281=PMID:7260241, GO:0005814=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0003824=PMID:10338144, GO:0003950=GO_REF:0000003} Q9Y6F1 "Poly ""ADP-ribose"" polymerase 3" protein 20030904 {GO:0006471=IEA, GO:0006281=TAS, GO:0005814=IEA, GO:0005634=IEA, GO:0003824=TAS, GO:0003950=IEA} DNA repair, protein ADP-ribosylation centriole, nucleus NAD+ ADP-ribosyltransferase activity, catalytic activity Human PARP4 HPA UniProtKB {GO:0005515=PMID:22190034, GO:0008219=PMID:12140175, GO:0042493=PMID:11291045, GO:0005634=PMID:10644454, GO:0003677=PMID:10100603, GO:0006974=PMID:10477748, GO:0003950=PMID:10477748, GO:0006471=PMID:10644454, GO:0005737=GO_REF:0000052, GO:0006954=PMID:12123754, GO:0006281=PMID:12101391, GO:0030529=PMID:11479319, GO:0006810=PMID:11855821, GO:0005876=PMID:10477748, GO:0019899=PMID:15169895, GO:0006464=PMID:10477748} Q9UKK3 "Poly ""ADP-ribose"" polymerase 4" protein 20081203 {GO:0005515=IPI, GO:0008219=IMP, GO:0042493=NAS, GO:0005634=NAS, GO:0003677=TAS, GO:0006974=NAS, GO:0003950=IDA, GO:0006471=NAS, GO:0005737=IDA, GO:0006954=IMP, GO:0006281=NAS, GO:0030529=NAS, GO:0006810=NAS, GO:0005876=IDA, GO:0019899=IDA, GO:0006464=IDA} DNA repair, cell death, cellular protein modification process, inflammatory response, protein ADP-ribosylation, response to DNA damage stimulus, response to drug, transport cytoplasm, nucleus, ribonucleoprotein complex, spindle microtubule DNA binding, NAD+ ADP-ribosyltransferase activity, enzyme binding, protein binding Human PARP6 UniProtKB UniProtKB {GO:0003950=GO_REF:0000003} Q2NL67 "Poly ""ADP-ribose"" polymerase 6" protein 20130413 {GO:0003950=IEA} NAD+ ADP-ribosyltransferase activity Human EC:2.4.2.30 PARP8 LIFEdb UniProtKB {GO:0005622=GO_REF:0000054, GO:0003950=GO_REF:0000003} Q8N3A8 "Poly ""ADP-ribose"" polymerase 8" protein 20100607 {GO:0005622=IDA, GO:0003950=IEA} intracellular NAD+ ADP-ribosyltransferase activity Human PARP9 UniProtKB UniProtKB {GO:0005515=PMID:23230272, GO:0005737=PMID:23230272, GO:0016477=PMID:11110709, GO:0005634=PMID:23230272, GO:0060330=PMID:16809771, GO:0006302=PMID:23230272, GO:0005829=GO_REF:0000039, GO:0003950=PMID:23230272} Q8IXQ6 "Poly ""ADP-ribose"" polymerase 9" protein 20130409 {GO:0005515=IPI, GO:0005737=IDA, GO:0016477=TAS, GO:0005634=IDA, GO:0060330=IDA, GO:0006302=IMP, GO:0005829=IEA, GO:0003950=IDA} cell migration, double-strand break repair, regulation of response to interferon-gamma cytoplasm, cytosol, nucleus NAD+ ADP-ribosyltransferase activity, protein binding Human PARS2 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0006433=GO_REF:0000002, GO:0005759=GO_REF:0000039, GO:0004827=GO_REF:0000003, GO:0005524=GO_REF:0000037, GO:0006418=Reactome:REACT_15482} Q7L3T8 Probable proline--tRNA ligase, mitochondrial protein 20130301 {GO:0010467=TAS, GO:0006433=IEA, GO:0005759=IEA, GO:0004827=IEA, GO:0005524=IEA, GO:0006418=TAS} gene expression, prolyl-tRNA aminoacylation, tRNA aminoacylation for protein translation mitochondrial matrix ATP binding, proline-tRNA ligase activity Human PARVA HPA UniProtKB {GO:0005515=PMID:23455922, GO:0030018=GO_REF:0000039, GO:0070252=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0034329=Reactome:REACT_20676, GO:0008360=GO_REF:0000037, GO:0071670=GO_REF:0000024, GO:0002040=GO_REF:0000024, GO:0003779=GO_REF:0000037, GO:0005634=GO_REF:0000019, GO:0015629=GO_REF:0000052, GO:0030027=GO_REF:0000019, GO:0005829=Reactome:REACT_20609, GO:0005737=GO_REF:0000052, GO:0007163=GO_REF:0000024, GO:0060271=PMID:20393563, GO:0003148=GO_REF:0000024, GO:0034446=PMID:11331308, GO:0034113=GO_REF:0000024, GO:0005925=GO_REF:0000052} Q9NVD7 Alpha-parvin protein 20101115 {GO:0005515=IPI, GO:0030018=IEA, GO:0070252=ISS, GO:0005886=IEA, GO:0034329=TAS, GO:0008360=IEA, GO:0071670=ISS, GO:0002040=ISS, GO:0003779=IEA, GO:0005634=IEA, GO:0015629=IDA, GO:0030027=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0007163=ISS, GO:0060271=IMP, GO:0003148=ISS, GO:0034446=IMP, GO:0034113=ISS, GO:0005925=IDA} actin-mediated cell contraction, cell junction assembly, cilium morphogenesis, establishment or maintenance of cell polarity, heterotypic cell-cell adhesion, outflow tract septum morphogenesis, regulation of cell shape, smooth muscle cell chemotaxis, sprouting angiogenesis, substrate adhesion-dependent cell spreading Z disc, actin cytoskeleton, cytoplasm, cytosol, focal adhesion, lamellipodium, nucleus, plasma membrane actin binding, protein binding Human PARVB Reactome UniProtKB {GO:0030018=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0031532=PMID:15005707, GO:0034329=Reactome:REACT_20676, GO:0030032=PMID:18325335, GO:0003779=GO_REF:0000037, GO:0030027=PMID:18325335, GO:0005829=Reactome:REACT_20672, GO:0030031=PMID:15005707, GO:0071963=PMID:15005707, GO:0007155=GO_REF:0000037, GO:0005856=GO_REF:0000039, GO:0005925=PMID:22869380} Q9HBI1 Beta-parvin protein 20130213 {GO:0030018=IEA, GO:0005886=IEA, GO:0031532=IMP, GO:0034329=TAS, GO:0030032=IMP, GO:0003779=IEA, GO:0030027=IDA, GO:0005829=TAS, GO:0030031=IMP, GO:0071963=IMP, GO:0007155=IEA, GO:0005856=IEA, GO:0005925=IDA} actin cytoskeleton reorganization, cell adhesion, cell junction assembly, cell projection assembly, establishment or maintenance of cell polarity regulating cell shape, lamellipodium assembly Z disc, cytoskeleton, cytosol, focal adhesion, lamellipodium, plasma membrane actin binding Human PARVG UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0007160=PMID:11171322, GO:0005886=GO_REF:0000039, GO:0003779=PMID:11171322, GO:0005856=PMID:11171322, GO:0005925=GO_REF:0000039} Q9HBI0 Gamma-parvin protein 20020307 {GO:0005737=IEA, GO:0007160=TAS, GO:0005886=IEA, GO:0003779=TAS, GO:0005856=TAS, GO:0005925=IEA} cell-matrix adhesion cytoplasm, cytoskeleton, focal adhesion, plasma membrane actin binding Human PASD1 LIFEdb UniProtKB {GO:0005634=GO_REF:0000054, GO:0004871=GO_REF:0000002} Q8IV76 PAS domain-containing protein 1 protein 20100607 {GO:0005634=IDA, GO:0004871=IEA} nucleus signal transducer activity Human PASK HPA UniProtKB {GO:0005515=PMID:17595531, GO:0005794=GO_REF:0000052, GO:0005634=PMID:17595531, GO:0045727=PMID:17595531, GO:0005524=GO_REF:0000037, GO:0045719=PMID:16275910, GO:0043576=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0046777=PMID:20943661, GO:0004674=PMID:20943661, GO:0006468=PMID:16275910, GO:0004871=GO_REF:0000002, GO:0035091=PMID:21418524, GO:2000505=GO_REF:0000024, GO:0070092=GO_REF:0000024} Q96RG2 PAS domain-containing serine/threonine-protein kinase protein 20090616 {GO:0005515=IPI, GO:0005794=IDA, GO:0005634=IDA, GO:0045727=TAS, GO:0005524=IEA, GO:0045719=IDA, GO:0043576=ISS, GO:0005737=IDA, GO:0046777=IDA, GO:0004674=IDA, GO:0006468=IDA, GO:0004871=IEA, GO:0035091=IDA, GO:2000505=ISS, GO:0070092=ISS} negative regulation of glycogen biosynthetic process, positive regulation of translation, protein autophosphorylation, protein phosphorylation, regulation of energy homeostasis, regulation of glucagon secretion, regulation of respiratory gaseous exchange Golgi apparatus, cytoplasm, nucleus ATP binding, phosphatidylinositol binding, protein binding, protein serine/threonine kinase activity, signal transducer activity Human PATE3 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} B3GLJ2 Prostate and testis expressed protein 3 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 PATL1 HPA UniProtKB {GO:0005515=PMID:20584987, GO:0010467=Reactome:REACT_71, GO:0033962=PMID:20584987, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=PMID:20826699, GO:0043928=Reactome:REACT_20518, GO:0000290=PMID:20852261, GO:0030014=PMID:20584987, GO:0043231=GO_REF:0000052, GO:0005829=Reactome:REACT_20560, GO:0008266=PMID:20826699, GO:0034046=PMID:20826699, GO:0016607=GO_REF:0000039, GO:0000932=PMID:20826699, GO:0016605=GO_REF:0000039, GO:0000288=Reactome:REACT_20639} Q86TB9 Protein PAT1 homolog 1 protein 20110516 {GO:0005515=IPI, GO:0010467=TAS, GO:0033962=IDA, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=IDA, GO:0043928=TAS, GO:0000290=IDA, GO:0030014=IDA, GO:0043231=IDA, GO:0005829=TAS, GO:0008266=IDA, GO:0034046=IDA, GO:0016607=IEA, GO:0000932=IDA, GO:0016605=IEA, GO:0000288=TAS} RNA metabolic process, cytoplasmic mRNA processing body assembly, deadenylation-dependent decapping of nuclear-transcribed mRNA, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay CCR4-NOT complex, PML body, cytoplasmic mRNA processing body, cytosol, intracellular membrane-bounded organelle, nuclear speck RNA binding, poly(G) RNA binding, poly(U) RNA binding, protein binding Human PATZ1 UniProtKB UniProtKB {GO:0006355=PMID:10713105, GO:0030217=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0005634=PMID:10713105, GO:0008270=GO_REF:0000002, GO:0007283=GO_REF:0000019, GO:0045893=GO_REF:0000019, GO:0003677=PMID:10949935, GO:0045892=PMID:10713105, GO:0008584=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q9HBE1 POZ-, AT hook-, and zinc finger-containing protein 1 protein 20050308 {GO:0006355=TAS, GO:0030217=IEA, GO:0003682=IEA, GO:0005634=TAS, GO:0008270=IEA, GO:0007283=IEA, GO:0045893=IEA, GO:0003677=NAS, GO:0045892=TAS, GO:0008584=IEA, GO:0006351=IEA} T cell differentiation, male gonad development, negative regulation of transcription, DNA-dependent, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, spermatogenesis, transcription, DNA-dependent nucleus DNA binding, chromatin binding, zinc ion binding Human PAWR HPA UniProtKB {GO:0005515=PMID:11755531, GO:0008285=PMID:8943350, GO:0043065=PMID:11585763, GO:0005886=GO_REF:0000052, GO:0003714=PMID:8943350, GO:0005884=GO_REF:0000024, GO:0030889=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0003779=GO_REF:0000024, GO:0005634=PMID:14627703, GO:0000122=PMID:8943350, GO:0006917=GO_REF:0000024, GO:0050860=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0042130=GO_REF:0000019, GO:0042986=GO_REF:0000019, GO:0042094=GO_REF:0000019, GO:0043522=PMID:14627703, GO:0005737=GO_REF:0000052, GO:0019899=PMID:15671026, GO:0051017=GO_REF:0000024} Q96IZ0 PRKC apoptosis WT1 regulator protein protein 20120912 {GO:0005515=IPI, GO:0008285=TAS, GO:0043065=NAS, GO:0005886=IDA, GO:0003714=TAS, GO:0005884=ISS, GO:0030889=IEA, GO:0006915=IEA, GO:0003779=ISS, GO:0005634=IDA, GO:0000122=TAS, GO:0006917=ISS, GO:0050860=IEA, GO:0006351=IEA, GO:0042130=IEA, GO:0042986=IEA, GO:0042094=IEA, GO:0043522=IPI, GO:0005737=IDA, GO:0019899=IDA, GO:0051017=ISS} actin filament bundle assembly, apoptotic process, induction of apoptosis, interleukin-2 biosynthetic process, negative regulation of B cell proliferation, negative regulation of T cell proliferation, negative regulation of T cell receptor signaling pathway, negative regulation of cell proliferation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of amyloid precursor protein biosynthetic process, positive regulation of apoptotic process, transcription, DNA-dependent actin filament, cytoplasm, nucleus, plasma membrane actin binding, enzyme binding, leucine zipper domain binding, protein binding, transcription corepressor activity Human PAX1 PINC UniProtKB {GO:0006366=PMID:1358810, GO:0008283=GO_REF:0000019, GO:0001756=GO_REF:0000019, GO:0043367=GO_REF:0000019, GO:0048538=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0060017=GO_REF:0000019, GO:0001501=PMID:9671740, GO:0043374=GO_REF:0000019, GO:0060349=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0061056=GO_REF:0000019} P15863 Paired box protein Pax-1 protein 20030904 {GO:0006366=TAS, GO:0008283=IEA, GO:0001756=IEA, GO:0043367=IEA, GO:0048538=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0060017=IEA, GO:0001501=TAS, GO:0043374=IEA, GO:0060349=IEA, GO:0045944=IEA, GO:0061056=IEA} CD4-positive, alpha-beta T cell differentiation, CD8-positive, alpha-beta T cell differentiation, bone morphogenesis, cell proliferation, parathyroid gland development, positive regulation of transcription from RNA polymerase II promoter, sclerotome development, skeletal system development, somitogenesis, thymus development, transcription from RNA polymerase II promoter nucleus DNA binding Human PAX2 ENSEMBL UniProtKB {GO:0005515=PMID:21575608, GO:0000987=GO_REF:0000019, GO:0001658=GO_REF:0000019, GO:0021554=GO_REF:0000024, GO:0070301=GO_REF:0000019, GO:0006366=PMID:8760285, GO:0044212=PMID:19048125, GO:0071300=GO_REF:0000019, GO:0034451=PMID:18000879, GO:0048793=GO_REF:0000024, GO:0001655=GO_REF:0000024, GO:0007409=PMID:9106533, GO:0005764=GO_REF:0000019, GO:0021650=GO_REF:0000019, GO:0072075=GO_REF:0000024, GO:0043069=GO_REF:0000024, GO:0072305=GO_REF:0000019, GO:0032993=GO_REF:0000019, GO:0072179=GO_REF:0000019, GO:0072177=GO_REF:0000019, GO:0072307=GO_REF:0000019, GO:0031667=GO_REF:0000019, GO:0072300=GO_REF:0000019, GO:0050679=PMID:17357786, GO:0003406=GO_REF:0000019, GO:0035799=GO_REF:0000019, GO:0042472=GO_REF:0000024, GO:0005815=PMID:18000879, GO:0001709=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0060231=GO_REF:0000024, GO:1900215=GO_REF:0000019, GO:0001843=GO_REF:0000019, GO:0039003=GO_REF:0000019, GO:1900218=GO_REF:0000019, GO:0007275=GO_REF:0000038, GO:0072207=PMID:7856737, GO:0000122=GO_REF:0000019, GO:1900212=GO_REF:0000024, GO:0072205=GO_REF:0000019, GO:0072108=GO_REF:0000019, GO:0061360=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0072289=GO_REF:0000019, GO:0072189=GO_REF:0000024, GO:0043491=GO_REF:0000019, GO:0002072=GO_REF:0000019, GO:0010001=GO_REF:0000019, GO:0070742=GO_REF:0000019, GO:0021633=GO_REF:0000019, GO:0045893=GO_REF:0000019, GO:2000378=PMID:17357786, GO:0035566=GO_REF:0000019, GO:0045892=PMID:19118900, GO:0021631=GO_REF:0000024, GO:0008284=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0072197=GO_REF:0000019, GO:0016175=GO_REF:0000019, GO:0045944=GO_REF:0000024, GO:0090102=GO_REF:0000024, GO:0090103=GO_REF:0000019, GO:0043010=GO_REF:0000024, GO:0071333=GO_REF:0000019, GO:0043154=PMID:17357786, GO:0090190=GO_REF:0000019, GO:0006355=GO_REF:0000038, GO:0043066=PMID:17357786, GO:0072172=GO_REF:0000019, GO:0001823=GO_REF:0000024, GO:0072593=GO_REF:0000019, GO:0003677=GO_REF:0000024, GO:0006351=GO_REF:0000024, GO:0072221=GO_REF:0000019, GO:0048854=GO_REF:0000019, GO:0048863=GO_REF:0000019, GO:0007501=GO_REF:0000019, GO:0003337=GO_REF:0000019, GO:2000594=GO_REF:0000019, GO:0031016=GO_REF:0000019, GO:0071364=GO_REF:0000019, GO:0061205=GO_REF:0000019, GO:0045918=PMID:19118900, GO:2000597=GO_REF:0000019, GO:0071260=GO_REF:0000019, GO:0007601=PMID:9106533, GO:0072162=GO_REF:0000019} Q5SZP1 Paired box protein Pax-2 protein 20130413 {GO:0005515=IPI, GO:0000987=IEA, GO:0001658=IEA, GO:0021554=ISS, GO:0070301=IEA, GO:0006366=TAS, GO:0044212=IDA, GO:0071300=IEA, GO:0034451=IDA, GO:0048793=ISS, GO:0001655=ISS, GO:0007409=TAS, GO:0005764=IEA, GO:0021650=IEA, GO:0072075=ISS, GO:0043069=ISS, GO:0072305=IEA, GO:0032993=IEA, GO:0072179=IEA, GO:0072177=IEA, GO:0072307=IEA, GO:0031667=IEA, GO:0072300=IEA, GO:0050679=IDA, GO:0003406=IEA, GO:0035799=IEA, GO:0042472=ISS, GO:0005815=IDA, GO:0001709=IEA, GO:0007568=IEA, GO:0060231=ISS, GO:1900215=IEA, GO:0001843=IEA, GO:0039003=IEA, GO:1900218=IEA, GO:0007275=IEA, GO:0072207=IEP, GO:0000122=IEA, GO:1900212=ISS, GO:0072205=IEA, GO:0072108=IEA, GO:0061360=IEA, GO:0043234=IEA, GO:0072289=IEA, GO:0072189=ISS, GO:0043491=IEA, GO:0002072=IEA, GO:0010001=IEA, GO:0070742=IEA, GO:0021633=IEA, GO:0045893=IEA, GO:2000378=IDA, GO:0035566=IEA, GO:0045892=IMP, GO:0021631=ISS, GO:0008284=IEA, GO:0005634=IEA, GO:0072197=IEA, GO:0016175=IEA, GO:0045944=ISS, GO:0090102=ISS, GO:0090103=IEA, GO:0043010=ISS, GO:0071333=IEA, GO:0043154=IDA, GO:0090190=IEA, GO:0006355=IEA, GO:0043066=IMP, GO:0072172=IEA, GO:0001823=ISS, GO:0072593=IEA, GO:0003677=ISS, GO:0006351=ISS, GO:0072221=IEA, GO:0048854=IEA, GO:0048863=IEA, GO:0007501=IEA, GO:0003337=IEA, GO:2000594=IEA, GO:0031016=IEA, GO:0071364=IEA, GO:0061205=IEA, GO:0045918=IMP, GO:2000597=IEA, GO:0071260=IEA, GO:0007601=TAS, GO:0072162=IEA} aging, axonogenesis, brain morphogenesis, branching involved in ureteric bud morphogenesis, camera-type eye development, cell fate determination, cellular response to epidermal growth factor stimulus, cellular response to glucose stimulus, cellular response to hydrogen peroxide, cellular response to mechanical stimulus, cellular response to retinoic acid, cochlea development, cochlea morphogenesis, glial cell differentiation, inner ear morphogenesis, mesenchymal to epithelial transition, mesenchymal to epithelial transition involved in metanephros morphogenesis, mesodermal cell fate specification, mesonephric duct development, mesonephric tubule formation, mesonephros development, metanephric collecting duct development, metanephric distal convoluted tubule development, metanephric epithelium development, metanephric mesenchymal cell differentiation, metanephric mesenchyme development, metanephric nephron tubule formation, multicellular organismal development, negative regulation of apoptotic process, negative regulation of apoptotic process involved in metanephric collecting duct development, negative regulation of apoptotic process involved in metanephric nephron tubule development, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of cytolysis, negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis, negative regulation of mesenchymal cell apoptotic process involved in metanephros development, negative regulation of programmed cell death, negative regulation of reactive oxygen species metabolic process, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, nephric duct formation, neural tube closure, optic chiasma development, optic cup morphogenesis involved in camera-type eye development, optic nerve development, optic nerve morphogenesis, optic nerve structural organization, pancreas development, paramesonephric duct development, positive regulation of branching involved in ureteric bud morphogenesis, positive regulation of cell proliferation, positive regulation of epithelial cell proliferation, positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis, positive regulation of metanephric DCT cell differentiation, positive regulation of metanephric glomerulus development, positive regulation of optic nerve formation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, pronephric field specification, pronephros development, protein kinase B signaling cascade, reactive oxygen species metabolic process, regulation of metanephric nephron tubule epithelial cell differentiation, regulation of metanephros size, regulation of transcription, DNA-dependent, response to nutrient levels, retinal pigment epithelium development, stem cell differentiation, transcription from RNA polymerase II promoter, transcription, DNA-dependent, ureter development, ureter maturation, ureter morphogenesis, urogenital system development, vestibulocochlear nerve formation, visual perception centriolar satellite, lysosome, microtubule organizing center, nucleus, protein complex, protein-DNA complex C2H2 zinc finger domain binding, DNA binding, core promoter proximal region sequence-specific DNA binding, protein binding, superoxide-generating NADPH oxidase activity, transcription regulatory region DNA binding Human Ensembl:ENSMUSP00000134661 PAX3 IntAct UniProtKB {GO:0005515=PMID:11029584, GO:0060594=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0006366=PMID:9500554, GO:0008283=GO_REF:0000019, GO:0003705=GO_REF:0000019, GO:0007605=PMID:9500554, GO:0001755=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0007507=GO_REF:0000019, GO:0045944=PMID:11863357, GO:0009887=PMID:8447316, GO:0048066=GO_REF:0000019, GO:0001843=GO_REF:0000019, GO:0006915=PMID:10871843, GO:0048663=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0021527=GO_REF:0000019, GO:0007399=GO_REF:0000037, GO:0043565=PMID:11863357, GO:0007517=GO_REF:0000037, GO:0003682=GO_REF:0000019, GO:0071837=GO_REF:0000019, GO:0045893=PMID:11863357} P23760 Paired box protein Pax-3 protein 20130415 {GO:0005515=IPI, GO:0060594=IEA, GO:0008284=IEA, GO:0003700=IEA, GO:0006366=TAS, GO:0008283=IEA, GO:0003705=IEA, GO:0007605=TAS, GO:0001755=IEA, GO:0005634=IEA, GO:0007507=IEA, GO:0045944=IDA, GO:0009887=TAS, GO:0048066=IEA, GO:0001843=IEA, GO:0006915=TAS, GO:0048663=IEA, GO:0000122=IEA, GO:0021527=IEA, GO:0007399=IEA, GO:0043565=IDA, GO:0007517=IEA, GO:0003682=IEA, GO:0071837=IEA, GO:0045893=IDA} apoptotic process, cell proliferation, developmental pigmentation, heart development, mammary gland specification, muscle organ development, negative regulation of transcription from RNA polymerase II promoter, nervous system development, neural crest cell migration, neural tube closure, neuron fate commitment, organ morphogenesis, positive regulation of cell proliferation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, sensory perception of sound, spinal cord association neuron differentiation, transcription from RNA polymerase II promoter nucleus HMG box domain binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, chromatin binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:P56693 PAX4 HPA UniProtKB {GO:0003700=GO_REF:0000002, GO:0060041=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0045597=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0007275=GO_REF:0000038, GO:0005634=GO_REF:0000052, GO:0000122=GO_REF:0000019, GO:0003677=PMID:9480859, GO:0051591=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0003690=GO_REF:0000019, GO:0031018=Reactome:REACT_13698, GO:0009887=PMID:9480859, GO:0007623=GO_REF:0000019, GO:0005654=Reactome:REACT_13802} O43316 Paired box protein Pax-4 protein 20080205 {GO:0003700=IEA, GO:0060041=IEA, GO:0042493=IEA, GO:0045597=IEA, GO:0005730=IDA, GO:0007275=IEA, GO:0005634=IDA, GO:0000122=IEA, GO:0003677=TAS, GO:0051591=IEA, GO:0006351=IEA, GO:0030154=IEA, GO:0043565=IEA, GO:0003690=IEA, GO:0031018=TAS, GO:0009887=TAS, GO:0007623=IEA, GO:0005654=TAS} cell differentiation, circadian rhythm, endocrine pancreas development, multicellular organismal development, negative regulation of transcription from RNA polymerase II promoter, organ morphogenesis, positive regulation of cell differentiation, response to cAMP, response to drug, retina development in camera-type eye, transcription, DNA-dependent nucleolus, nucleoplasm, nucleus DNA binding, double-stranded DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity NOT Human PAX5 PINC UniProtKB {GO:0006355=GO_REF:0000002, GO:0003700=GO_REF:0000019, GO:0006366=PMID:10524622, GO:0007275=PMID:10524629, GO:0005634=GO_REF:0000039, GO:0000122=GO_REF:0000019, GO:0007283=GO_REF:0000037, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000038, GO:0030154=GO_REF:0000037, GO:0007399=GO_REF:0000037, GO:0006959=PMID:10524629, GO:0045944=GO_REF:0000019, GO:0051573=GO_REF:0000019, GO:0009887=PMID:10524622} Q02548 Paired box protein Pax-5 protein 20031120 {GO:0006355=IEA, GO:0003700=IEA, GO:0006366=TAS, GO:0007275=TAS, GO:0005634=IEA, GO:0000122=IEA, GO:0007283=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0030154=IEA, GO:0007399=IEA, GO:0006959=TAS, GO:0045944=IEA, GO:0051573=IEA, GO:0009887=TAS} cell differentiation, humoral immune response, multicellular organismal development, negative regulation of histone H3-K9 methylation, negative regulation of transcription from RNA polymerase II promoter, nervous system development, organ morphogenesis, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, spermatogenesis, transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity Human PAX6 GOC UniProtKB {GO:0005515=PMID:16098226, GO:0004842=GO_REF:0000024, GO:0000790=PMID:20592023, GO:0003700=PMID:10441571, GO:0006366=PMID:20592023, GO:0001654=PMID:10747901, GO:0000981=PMID:20592023, GO:0048708=GO_REF:0000019, GO:0050680=GO_REF:0000019, GO:0048596=GO_REF:0000019, GO:0007224=GO_REF:0000019, GO:0021796=GO_REF:0000019, GO:0003690=GO_REF:0000019, GO:0021798=GO_REF:0000019, GO:0021797=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0009887=PMID:10441571, GO:0031625=GO_REF:0000019, GO:0030334=GO_REF:0000019, GO:0035035=GO_REF:0000024, GO:0048505=GO_REF:0000019, GO:0019901=GO_REF:0000024, GO:0001709=GO_REF:0000019, GO:0023019=GO_REF:0000019, GO:0007275=GO_REF:0000038, GO:0003322=PMID:20592023, GO:0007417=PMID:10747901, GO:0000979=PMID:20592023, GO:0071837=GO_REF:0000019, GO:0045893=PMID:20592023, GO:0042462=GO_REF:0000019, GO:0008134=GO_REF:0000024, GO:0016567=GO_REF:0000024, GO:0021983=GO_REF:0000019, GO:0061072=PMID:7550230, GO:0042660=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0009950=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0021778=GO_REF:0000019, GO:0030858=GO_REF:0000019, GO:0050768=GO_REF:0000024, GO:0002088=GO_REF:0000019, GO:0045944=GO_REF:0000024, GO:0021905=GO_REF:0000019, GO:0021902=GO_REF:0000019, GO:0007435=GO_REF:0000019, GO:0006355=GO_REF:0000038, GO:0001568=PMID:7550230, GO:0033365=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0070410=GO_REF:0000019, GO:0009611=PMID:17982423, GO:0002052=GO_REF:0000019, GO:0070412=PMID:17251190, GO:0048663=PMID:17291498, GO:0042593=PMID:11756345, GO:0003677=PMID:10441571, GO:0006351=GO_REF:0000038, GO:0010628=PMID:20592023, GO:0061303=PMID:7550230, GO:0043565=GO_REF:0000002, GO:0032808=GO_REF:0000019, GO:0003680=GO_REF:0000019, GO:0045665=GO_REF:0000019, GO:0030216=GO_REF:0000019, GO:0021918=GO_REF:0000019, GO:0001764=GO_REF:0000019, GO:0007601=PMID:10441571, GO:0021912=GO_REF:0000019, GO:0030902=GO_REF:0000019, GO:0021913=GO_REF:0000019} P26367 Paired box protein Pax-6 protein 20130413 {GO:0005515=IPI, GO:0004842=ISS, GO:0000790=IDA, GO:0003700=TAS, GO:0006366=IMP, GO:0001654=TAS, GO:0000981=IDA, GO:0048708=IEA, GO:0050680=IEA, GO:0048596=IEA, GO:0007224=IEA, GO:0021796=IEA, GO:0003690=IEA, GO:0021798=IEA, GO:0021797=IEA, GO:0007411=IEA, GO:0009887=TAS, GO:0031625=IEA, GO:0030334=IEA, GO:0035035=ISS, GO:0048505=IEA, GO:0019901=ISS, GO:0001709=IEA, GO:0023019=IEA, GO:0007275=IEA, GO:0003322=IMP, GO:0007417=TAS, GO:0000979=IDA, GO:0071837=IEA, GO:0045893=IMP, GO:0042462=IEA, GO:0008134=ISS, GO:0016567=ISS, GO:0021983=IEA, GO:0061072=IMP, GO:0042660=IEA, GO:0005634=IDA, GO:0009950=IEA, GO:0005737=IDA, GO:0021778=IEA, GO:0030858=IEA, GO:0050768=ISS, GO:0002088=IEA, GO:0045944=ISS, GO:0021905=IEA, GO:0021902=IEA, GO:0007435=IEA, GO:0006355=IEA, GO:0001568=IMP, GO:0033365=IEA, GO:0005730=IDA, GO:0070410=IEA, GO:0009611=IEP, GO:0002052=IEA, GO:0070412=IPI, GO:0048663=NAS, GO:0042593=IMP, GO:0003677=TAS, GO:0006351=IEA, GO:0010628=IMP, GO:0061303=IMP, GO:0043565=IEA, GO:0032808=IEA, GO:0003680=IEA, GO:0045665=IEA, GO:0030216=IEA, GO:0021918=IEA, GO:0001764=IEA, GO:0007601=TAS, GO:0021912=IEA, GO:0030902=IEA, GO:0021913=IEA} astrocyte differentiation, axon guidance, blood vessel development, cell fate determination, central nervous system development, cerebral cortex regionalization, commitment of neuronal cell to specific neuron type in forebrain, cornea development in camera-type eye, dorsal/ventral axis specification, embryonic camera-type eye morphogenesis, eye development, eye photoreceptor cell development, forebrain anterior/posterior pattern specification, forebrain dorsal/ventral pattern formation, forebrain-midbrain boundary formation, glucose homeostasis, hindbrain development, iris morphogenesis, keratinocyte differentiation, lacrimal gland development, lens development in camera-type eye, multicellular organismal development, negative regulation of epithelial cell proliferation, negative regulation of neurogenesis, negative regulation of neuron differentiation, neuron fate commitment, neuron migration, oligodendrocyte cell fate specification, organ morphogenesis, pancreatic A cell development, pituitary gland development, positive regulation of cell fate specification, positive regulation of epithelial cell differentiation, positive regulation of gene expression, positive regulation of neuroblast proliferation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein localization to organelle, protein ubiquitination, regulation of cell migration, regulation of timing of cell differentiation, regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment, regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification, regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification, regulation of transcription, DNA-dependent, response to wounding, salivary gland morphogenesis, signal transduction involved in regulation of gene expression, smoothened signaling pathway, transcription from RNA polymerase II promoter, transcription, DNA-dependent, visual perception cytoplasm, nuclear chromatin, nucleolus, nucleus AT DNA binding, DNA binding, HMG box domain binding, R-SMAD binding, RNA polymerase II core promoter sequence-specific DNA binding, co-SMAD binding, double-stranded DNA binding, histone acetyltransferase binding, protein binding, protein kinase binding, sequence-specific DNA binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity, transcription factor binding, ubiquitin protein ligase binding, ubiquitin-protein ligase activity Human UniProtKB:Q99PQ2 PAX7 PINC UniProtKB {GO:0043066=PMID:10871843, GO:0014813=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0060415=GO_REF:0000019, GO:0051216=GO_REF:0000019, GO:0048706=GO_REF:0000019, GO:0007275=GO_REF:0000038, GO:0005634=GO_REF:0000039, GO:0048663=GO_REF:0000019, GO:0009653=PMID:9339373, GO:0006351=GO_REF:0000037, GO:0021527=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0021904=GO_REF:0000019, GO:0043403=GO_REF:0000019} P23759 Paired box protein Pax-7 protein 20031119 {GO:0043066=TAS, GO:0014813=IEA, GO:0003700=IEA, GO:0060415=IEA, GO:0051216=IEA, GO:0048706=IEA, GO:0007275=IEA, GO:0005634=IEA, GO:0048663=IEA, GO:0009653=TAS, GO:0006351=IEA, GO:0021527=IEA, GO:0043565=IEA, GO:0021904=IEA, GO:0043403=IEA} anatomical structure morphogenesis, cartilage development, dorsal/ventral neural tube patterning, embryonic skeletal system development, multicellular organismal development, muscle tissue morphogenesis, negative regulation of apoptotic process, neuron fate commitment, satellite cell commitment, skeletal muscle tissue regeneration, spinal cord association neuron differentiation, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human PAX8 HPA UniProtKB {GO:0005515=PMID:20195357, GO:0001658=PMID:1337742, GO:0003700=PMID:9590296, GO:0044212=PMID:15356023, GO:0048793=GO_REF:0000024, GO:0001655=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0030878=PMID:9590296, GO:0009653=PMID:9590296, GO:0030154=GO_REF:0000019, GO:0072278=PMID:1337742, GO:0072305=GO_REF:0000024, GO:0071371=PMID:15961562, GO:0045944=PMID:9388203, GO:0004996=PMID:9590296, GO:0072307=GO_REF:0000024, GO:2000612=PMID:15356023, GO:2000611=PMID:15356023, GO:0090190=GO_REF:0000024, GO:0042472=GO_REF:0000024, GO:0001822=PMID:15494458, GO:0071599=PMID:15494458, GO:0001823=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0039003=GO_REF:0000024, GO:1900215=GO_REF:0000024, GO:0042981=GO_REF:0000024, GO:1900218=GO_REF:0000024, GO:0072207=PMID:7856737, GO:1900212=GO_REF:0000024, GO:0007417=PMID:15494458, GO:0000979=PMID:9388203, GO:0003677=PMID:9590296, GO:0072108=GO_REF:0000024, GO:0006351=PMID:9590296, GO:0072221=GO_REF:0000024, GO:0003337=PMID:8861958, GO:0072289=GO_REF:0000024, GO:0072284=PMID:1337742, GO:2000594=GO_REF:0000024, GO:0072050=GO_REF:0000019, GO:0005654=GO_REF:0000024, GO:0045893=PMID:15356023, GO:0072164=GO_REF:0000019} Q06710 Paired box protein Pax-8 protein 20101115 {GO:0005515=IPI, GO:0001658=IEP, GO:0003700=IDA, GO:0044212=IDA, GO:0048793=ISS, GO:0001655=ISS, GO:0005634=IDA, GO:0030878=IMP, GO:0009653=TAS, GO:0030154=IEA, GO:0072278=IEP, GO:0072305=ISS, GO:0071371=IDA, GO:0045944=IDA, GO:0004996=TAS, GO:0072307=ISS, GO:2000612=IMP, GO:2000611=IMP, GO:0090190=ISS, GO:0042472=ISS, GO:0001822=IEP, GO:0071599=IEP, GO:0001823=ISS, GO:0005730=IDA, GO:0039003=ISS, GO:1900215=ISS, GO:0042981=ISS, GO:1900218=ISS, GO:0072207=IEP, GO:1900212=ISS, GO:0007417=IEP, GO:0000979=IDA, GO:0003677=IMP, GO:0072108=ISS, GO:0006351=IDA, GO:0072221=ISS, GO:0003337=IEP, GO:0072289=ISS, GO:0072284=IEP, GO:2000594=ISS, GO:0072050=IEA, GO:0005654=ISS, GO:0045893=IDA, GO:0072164=IEA} S-shaped body morphogenesis, anatomical structure morphogenesis, branching involved in ureteric bud morphogenesis, cell differentiation, cellular response to gonadotropin stimulus, central nervous system development, inner ear morphogenesis, kidney development, mesenchymal to epithelial transition involved in metanephros morphogenesis, mesonephric tubule development, mesonephros development, metanephric S-shaped body morphogenesis, metanephric comma-shaped body morphogenesis, metanephric distal convoluted tubule development, metanephric epithelium development, metanephric nephron tubule formation, negative regulation of apoptotic process involved in metanephric collecting duct development, negative regulation of apoptotic process involved in metanephric nephron tubule development, negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis, negative regulation of mesenchymal cell apoptotic process involved in metanephros development, otic vesicle development, positive regulation of branching involved in ureteric bud morphogenesis, positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis, positive regulation of metanephric DCT cell differentiation, positive regulation of thyroid hormone generation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, pronephric field specification, pronephros development, regulation of apoptotic process, regulation of metanephric nephron tubule epithelial cell differentiation, regulation of thyroid-stimulating hormone secretion, thyroid gland development, transcription, DNA-dependent, urogenital system development nucleolus, nucleoplasm, nucleus DNA binding, RNA polymerase II core promoter sequence-specific DNA binding, protein binding, sequence-specific DNA binding transcription factor activity, thyroid-stimulating hormone receptor activity, transcription regulatory region DNA binding NOT Human PAX9 HPA UniProtKB {GO:0005515=PMID:12657635, GO:0006355=GO_REF:0000029, GO:0042481=GO_REF:0000019, GO:0007275=GO_REF:0000029, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000029, GO:0006351=GO_REF:0000037, GO:0005739=GO_REF:0000052, GO:0007492=GO_REF:0000019, GO:0060325=GO_REF:0000019, GO:0071363=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0042476=GO_REF:0000019, GO:0045892=PMID:12657635} P55771 Paired box protein Pax-9 protein 20110516 {GO:0005515=IPI, GO:0006355=NAS, GO:0042481=IEA, GO:0007275=NAS, GO:0005634=IDA, GO:0003677=NAS, GO:0006351=IEA, GO:0005739=IDA, GO:0007492=IEA, GO:0060325=IEA, GO:0071363=IEA, GO:0045944=IEA, GO:0042476=IEA, GO:0045892=IDA} cellular response to growth factor stimulus, endoderm development, face morphogenesis, multicellular organismal development, negative regulation of transcription, DNA-dependent, odontogenesis, positive regulation of transcription from RNA polymerase II promoter, regulation of odontogenesis, regulation of transcription, DNA-dependent, transcription, DNA-dependent mitochondrion, nucleus DNA binding, protein binding Human PAXIP1 IntAct UniProtKB {GO:0005515=PMID:19124460, GO:0000416=GO_REF:0000024, GO:0030330=PMID:17690115, GO:0006310=GO_REF:0000037, GO:0005634=PMID:17690115, GO:0060261=PMID:17925232, GO:0035066=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0016363=GO_REF:0000039, GO:0035097=PMID:17925232, GO:0006281=GO_REF:0000037, GO:0051571=GO_REF:0000024, GO:0043542=GO_REF:0000019, GO:0010212=PMID:15456759, GO:0045830=GO_REF:0000024, GO:0031398=GO_REF:0000024, GO:0060717=GO_REF:0000019, GO:0001570=GO_REF:0000019, GO:0060612=GO_REF:0000019, GO:0051568=PMID:17178841} Q6ZW49 PAX-interacting protein 1 protein 20130415 {GO:0005515=IPI, GO:0000416=ISS, GO:0030330=IMP, GO:0006310=IEA, GO:0005634=IDA, GO:0060261=IMP, GO:0035066=ISS, GO:0006351=IEA, GO:0016363=IEA, GO:0035097=IDA, GO:0006281=IEA, GO:0051571=ISS, GO:0043542=IEA, GO:0010212=IDA, GO:0045830=ISS, GO:0031398=ISS, GO:0060717=IEA, GO:0001570=IEA, GO:0060612=IEA, GO:0051568=IDA} DNA damage response, signal transduction by p53 class mediator, DNA recombination, DNA repair, adipose tissue development, chorion development, endothelial cell migration, histone H3-K4 methylation, positive regulation of histone H3-K36 methylation, positive regulation of histone H3-K4 methylation, positive regulation of histone acetylation, positive regulation of isotype switching, positive regulation of protein ubiquitination, positive regulation of transcription initiation from RNA polymerase II promoter, response to ionizing radiation, transcription, DNA-dependent, vasculogenesis histone methyltransferase complex, nuclear matrix, nucleus protein binding Human UniProtKB:Q9BTK6 PBK IntAct UniProtKB {GO:0005515=PMID:20622899, GO:0007067=PMID:10779557, GO:0004674=PMID:10779557, GO:0006468=GO_REF:0000029, GO:0005575=GO_REF:0000015, GO:0005524=GO_REF:0000029} Q96KB5 Lymphokine-activated killer T-cell-originated protein kinase protein 20130415 {GO:0005515=IPI, GO:0007067=NAS, GO:0004674=TAS, GO:0006468=NAS, GO:0005575=ND, GO:0005524=NAS} mitosis, protein phosphorylation cellular_component ATP binding, protein binding, protein serine/threonine kinase activity Human UniProtKB:P04637 PBLD UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0009058=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0016853=GO_REF:0000037, GO:0003824=GO_REF:0000002} P30039 Phenazine biosynthesis-like domain-containing protein protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0009058=IEA, GO:0005575=ND, GO:0016853=IEA, GO:0003824=IEA} biological_process, biosynthetic process cellular_component catalytic activity, isomerase activity, molecular_function Human PBRM1 UniProtKB UniProtKB {GO:0007507=GO_REF:0000019, GO:0007067=PMID:11078522, GO:0006355=GO_REF:0000037, GO:0008285=PMID:21248752, GO:0003682=PMID:11078522, GO:0000776=GO_REF:0000019, GO:0006338=PMID:11078522, GO:0000228=PMID:11078522, GO:0001890=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q86U86 Protein polybromo-1 protein 20110128 {GO:0007507=IEA, GO:0007067=TAS, GO:0006355=IEA, GO:0008285=IMP, GO:0003682=NAS, GO:0000776=IEA, GO:0006338=TAS, GO:0000228=NAS, GO:0001890=IEA, GO:0003677=IEA, GO:0006351=IEA} chromatin remodeling, heart development, mitosis, negative regulation of cell proliferation, placenta development, regulation of transcription, DNA-dependent, transcription, DNA-dependent kinetochore, nuclear chromosome DNA binding, chromatin binding Human PBX1 HPA UniProtKB {GO:0005515=PMID:15684392, GO:0008284=GO_REF:0000019, GO:0001658=GO_REF:0000019, GO:0006694=GO_REF:0000037, GO:0003700=GO_REF:0000002, GO:0030325=GO_REF:0000019, GO:0048706=GO_REF:0000019, GO:0009954=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0048538=GO_REF:0000019, GO:0030326=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0048536=GO_REF:0000019, GO:0005737=PMID:18973687, GO:0030278=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0009887=GO_REF:0000019, GO:0007548=GO_REF:0000037, GO:0035162=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0003677=PMID:10052460, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000019, GO:0045665=GO_REF:0000019} P40424 Pre-B-cell leukemia transcription factor 1 protein 20080205 {GO:0005515=IPI, GO:0008284=IEA, GO:0001658=IEA, GO:0006694=IEA, GO:0003700=IEA, GO:0030325=IEA, GO:0048706=IEA, GO:0009954=IEA, GO:0005634=IDA, GO:0048538=IEA, GO:0030326=IEA, GO:0009952=IEA, GO:0048536=IEA, GO:0005737=IDA, GO:0030278=IEA, GO:0045944=IEA, GO:0009887=IEA, GO:0007548=IEA, GO:0035162=IEA, GO:0005667=IEA, GO:0046982=IEA, GO:0005730=IDA, GO:0003677=IDA, GO:0006351=IEA, GO:0043565=IEA, GO:0045665=IEA} adrenal gland development, anterior/posterior pattern specification, branching involved in ureteric bud morphogenesis, embryonic hemopoiesis, embryonic limb morphogenesis, embryonic skeletal system development, negative regulation of neuron differentiation, organ morphogenesis, positive regulation of cell proliferation, positive regulation of transcription from RNA polymerase II promoter, proximal/distal pattern formation, regulation of ossification, sex differentiation, spleen development, steroid biosynthetic process, thymus development, transcription, DNA-dependent cytoplasm, nucleolus, nucleus, transcription factor complex DNA binding, protein binding, protein heterodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity NOT Human PBX2 UniProtKB UniProtKB {GO:0043565=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0005634=PMID:18973687, GO:0009954=GO_REF:0000019, GO:0030326=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0008134=PMID:18973687} P40425 Pre-B-cell leukemia transcription factor 2 protein 20100322 {GO:0043565=IEA, GO:0005667=IEA, GO:0003700=IEA, GO:0045944=IEA, GO:0003682=IEA, GO:0005634=IDA, GO:0009954=IEA, GO:0030326=IEA, GO:0006351=IEA, GO:0008134=IPI} embryonic limb morphogenesis, positive regulation of transcription from RNA polymerase II promoter, proximal/distal pattern formation, transcription, DNA-dependent nucleus, transcription factor complex chromatin binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human UniProtKB:P31268 PBX3 InterPro UniProtKB {GO:0007388=PMID:1682799, GO:0043565=GO_REF:0000002, GO:0008344=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0002087=GO_REF:0000019, GO:0007387=PMID:1682799, GO:0003700=GO_REF:0000002, GO:0007585=GO_REF:0000019, GO:0048666=GO_REF:0000019, GO:0005634=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0021516=GO_REF:0000019} Q5JS98 Pre-B-cell leukemia transcription factor 3 protein 20130413 {GO:0007388=TAS, GO:0043565=IEA, GO:0008344=IEA, GO:0005667=IEA, GO:0002087=IEA, GO:0007387=TAS, GO:0003700=IEA, GO:0007585=IEA, GO:0048666=IEA, GO:0005634=IEA, GO:0006351=IEA, GO:0021516=IEA} adult locomotory behavior, anterior compartment pattern formation, dorsal spinal cord development, neuron development, posterior compartment specification, regulation of respiratory gaseous exchange by neurological system process, respiratory gaseous exchange, transcription, DNA-dependent nucleus, transcription factor complex sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human InterPro:IPR001356 PBXIP1 HPA UniProtKB {GO:0005515=PMID:19060904, GO:0005737=GO_REF:0000052, GO:0003714=PMID:10825160, GO:0005874=GO_REF:0000037, GO:0007275=PMID:10825160, GO:0005634=PMID:10825160, GO:0045892=PMID:10825160, GO:0030154=PMID:10825160, GO:0005829=PMID:10825160, GO:0043231=GO_REF:0000052} Q96AQ6 Pre-B-cell leukemia transcription factor-interacting protein 1 protein 20101115 {GO:0005515=IPI, GO:0005737=IDA, GO:0003714=NAS, GO:0005874=IEA, GO:0007275=NAS, GO:0005634=NAS, GO:0045892=NAS, GO:0030154=NAS, GO:0005829=NAS, GO:0043231=IDA} cell differentiation, multicellular organismal development, negative regulation of transcription, DNA-dependent cytoplasm, cytosol, intracellular membrane-bounded organelle, microtubule, nucleus protein binding, transcription corepressor activity Human PC Reactome UniProtKB {GO:0006629=GO_REF:0000037, GO:0005975=Reactome:REACT_474, GO:0006094=Reactome:REACT_1520, GO:0005743=GO_REF:0000019, GO:0006107=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000019, GO:0003677=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0005739=PMID:16729965, GO:0006090=GO_REF:0000019, GO:0005759=Reactome:REACT_1895, GO:0004736=Reactome:REACT_1895, GO:0009374=GO_REF:0000019, GO:0006006=Reactome:REACT_723, GO:0004075=GO_REF:0000002} P11498 Pyruvate carboxylase, mitochondrial protein 20130121 {GO:0006629=IEA, GO:0005975=TAS, GO:0006094=TAS, GO:0005743=IEA, GO:0006107=IEA, GO:0044281=TAS, GO:0005524=IEA, GO:0003677=IEA, GO:0046872=IEA, GO:0005739=IDA, GO:0006090=IEA, GO:0005759=TAS, GO:0004736=TAS, GO:0009374=IEA, GO:0006006=TAS, GO:0004075=IEA} carbohydrate metabolic process, gluconeogenesis, glucose metabolic process, lipid metabolic process, oxaloacetate metabolic process, pyruvate metabolic process, small molecule metabolic process mitochondrial inner membrane, mitochondrial matrix, mitochondrion ATP binding, DNA binding, biotin binding, biotin carboxylase activity, metal ion binding, pyruvate carboxylase activity Human PCBD1 HPA UniProtKB {GO:0005515=PMID:20195357, GO:0043496=GO_REF:0000019, GO:0006559=Reactome:REACT_1786, GO:0006729=GO_REF:0000037, GO:0003713=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0004505=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0051291=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0042802=PMID:16189514, GO:0005829=Reactome:REACT_2236, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000052, GO:0051289=GO_REF:0000019, GO:0045893=GO_REF:0000019, GO:0008124=Reactome:REACT_2236} P61457 Pterin-4-alpha-carbinolamine dehydratase protein 20110516 {GO:0005515=IPI, GO:0043496=IEA, GO:0006559=TAS, GO:0006729=IEA, GO:0003713=IEA, GO:0005730=IDA, GO:0004505=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0051291=IEA, GO:0006351=IEA, GO:0042802=IPI, GO:0005829=TAS, GO:0034641=TAS, GO:0005737=IDA, GO:0051289=IEA, GO:0045893=IEA, GO:0008124=EXP} L-phenylalanine catabolic process, cellular nitrogen compound metabolic process, positive regulation of transcription, DNA-dependent, protein heterooligomerization, protein homotetramerization, regulation of protein homodimerization activity, small molecule metabolic process, tetrahydrobiopterin biosynthetic process, transcription, DNA-dependent cytoplasm, cytosol, nucleolus, nucleus 4-alpha-hydroxytetrahydrobiopterin dehydratase activity, identical protein binding, phenylalanine 4-monooxygenase activity, protein binding, transcription coactivator activity Human PCBD2 IntAct UniProtKB {GO:0005515=PMID:11980910, GO:0005739=GO_REF:0000019, GO:0051289=GO_REF:0000019, GO:0006729=GO_REF:0000037, GO:0004505=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0045893=PMID:11980910, GO:0008124=GO_REF:0000003, GO:0051291=GO_REF:0000019} Q9H0N5 Pterin-4-alpha-carbinolamine dehydratase 2 protein 20130415 {GO:0005515=IPI, GO:0005739=IEA, GO:0051289=IEA, GO:0006729=IEA, GO:0004505=IEA, GO:0005634=IEA, GO:0005575=ND, GO:0045893=IDA, GO:0008124=IEA, GO:0051291=IEA} positive regulation of transcription, DNA-dependent, protein heterooligomerization, protein homotetramerization, tetrahydrobiopterin biosynthetic process cellular_component, mitochondrion, nucleus 4-alpha-hydroxytetrahydrobiopterin dehydratase activity, phenylalanine 4-monooxygenase activity, protein binding Human UniProtKB:Q9Y463 PCBP1 IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0005737=GO_REF:0000029, GO:0003697=PMID:8152927, GO:0000398=Reactome:REACT_467, GO:0016071=GO_REF:0000029, GO:0003723=PMID:7556077, GO:0030529=GO_REF:0000037, GO:0005654=Reactome:REACT_1935, GO:0005634=GO_REF:0000029} Q15365 Poly(rC)-binding protein 1 protein 20130415 {GO:0005515=IPI, GO:0008380=TAS, GO:0010467=TAS, GO:0005737=NAS, GO:0003697=IDA, GO:0000398=TAS, GO:0016071=NAS, GO:0003723=IDA, GO:0030529=IEA, GO:0005654=TAS, GO:0005634=NAS} RNA splicing, gene expression, mRNA metabolic process, mRNA splicing, via spliceosome cytoplasm, nucleoplasm, nucleus, ribonucleoprotein complex RNA binding, protein binding, single-stranded DNA binding Human UniProtKB:Q9Y3Q8 PCBP2 HPA UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:16713569, GO:0010467=Reactome:REACT_71, GO:0050687=PMID:19881509, GO:0016071=PMID:7556077, GO:0003723=PMID:7607214, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0005829=Reactome:REACT_25398, GO:0005737=GO_REF:0000052, GO:0051607=GO_REF:0000037, GO:0000398=Reactome:REACT_467, GO:0045087=Reactome:REACT_6802, GO:0030529=GO_REF:0000037, GO:0005654=Reactome:REACT_1935, GO:0043161=PMID:19881509, GO:0019899=PMID:19881509, GO:0032480=Reactome:REACT_25271, GO:0031625=PMID:19881509} Q15366 Poly(rC)-binding protein 2 protein 20110516 {GO:0008380=TAS, GO:0005515=IPI, GO:0010467=TAS, GO:0050687=IMP, GO:0016071=NAS, GO:0003723=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0051607=IEA, GO:0000398=TAS, GO:0045087=TAS, GO:0030529=IEA, GO:0005654=TAS, GO:0043161=IMP, GO:0019899=IPI, GO:0032480=TAS, GO:0031625=IPI} RNA splicing, defense response to virus, gene expression, innate immune response, mRNA metabolic process, mRNA splicing, via spliceosome, negative regulation of defense response to virus, negative regulation of type I interferon production, proteasomal ubiquitin-dependent protein catabolic process cytoplasm, cytosol, nucleolus, nucleoplasm, nucleus, ribonucleoprotein complex DNA binding, RNA binding, enzyme binding, protein binding, ubiquitin protein ligase binding Human PCBP3 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0016071=PMID:7556077, GO:0030529=GO_REF:0000037, GO:0003723=PMID:10936052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0005829=PMID:16780588, GO:0043231=GO_REF:0000052} P57721 Poly(rC)-binding protein 3 protein 20101115 {GO:0005739=IDA, GO:0016071=NAS, GO:0030529=IEA, GO:0003723=NAS, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0005829=IDA, GO:0043231=IDA} mRNA metabolic process cytosol, intracellular membrane-bounded organelle, mitochondrion, nucleolus, nucleus, ribonucleoprotein complex DNA binding, RNA binding Human PCBP4 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0008630=PMID:10891498, GO:0030529=GO_REF:0000037, GO:0003723=PMID:10891498, GO:0007050=PMID:10891498, GO:0005575=GO_REF:0000015, GO:0003677=GO_REF:0000037, GO:0006977=PMID:10891498} Q9GZT1 Poly(rC)-binding protein 4 protein 20010830 {GO:0005737=IEA, GO:0008630=IDA, GO:0030529=IEA, GO:0003723=IDA, GO:0007050=IDA, GO:0005575=ND, GO:0003677=IEA, GO:0006977=IDA} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, cell cycle arrest, intrinsic apoptotic signaling pathway in response to DNA damage cellular_component, cytoplasm, ribonucleoprotein complex DNA binding, RNA binding Human PCCA Reactome UniProtKB {GO:0006635=Reactome:REACT_1473, GO:0004658=GO_REF:0000003, GO:0005576=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000002, GO:0019836=GO_REF:0000002, GO:0005759=Reactome:REACT_580, GO:0009374=PMID:3460076, GO:0004075=GO_REF:0000002, GO:0019626=Reactome:REACT_993, GO:0019899=PMID:19157941, GO:0044255=Reactome:REACT_22279} P05165 Propionyl-CoA carboxylase alpha chain, mitochondrial protein 20130121 {GO:0006635=TAS, GO:0004658=IEA, GO:0005576=IEA, GO:0044281=TAS, GO:0005524=IEA, GO:0046872=IEA, GO:0019836=IEA, GO:0005759=TAS, GO:0009374=TAS, GO:0004075=IEA, GO:0019626=TAS, GO:0019899=IPI, GO:0044255=TAS} cellular lipid metabolic process, fatty acid beta-oxidation, hemolysis by symbiont of host erythrocytes, short-chain fatty acid catabolic process, small molecule metabolic process extracellular region, mitochondrial matrix ATP binding, biotin binding, biotin carboxylase activity, enzyme binding, metal ion binding, propionyl-CoA carboxylase activity Human PCCB Reactome UniProtKB {GO:0005739=PMID:8188292, GO:0006635=Reactome:REACT_1473, GO:0009317=GO_REF:0000002, GO:0005759=Reactome:REACT_580, GO:0016874=GO_REF:0000002, GO:0004658=GO_REF:0000003, GO:0019626=Reactome:REACT_993, GO:0006633=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0003989=GO_REF:0000002, GO:0044255=Reactome:REACT_22279} P05166 Propionyl-CoA carboxylase beta chain, mitochondrial protein 20130121 {GO:0005739=TAS, GO:0006635=TAS, GO:0009317=IEA, GO:0005759=TAS, GO:0016874=IEA, GO:0004658=IEA, GO:0019626=TAS, GO:0006633=IEA, GO:0044281=TAS, GO:0005524=IEA, GO:0003989=IEA, GO:0044255=TAS} cellular lipid metabolic process, fatty acid beta-oxidation, fatty acid biosynthetic process, short-chain fatty acid catabolic process, small molecule metabolic process acetyl-CoA carboxylase complex, mitochondrial matrix, mitochondrion ATP binding, acetyl-CoA carboxylase activity, ligase activity, propionyl-CoA carboxylase activity Human PCDH1 PINC UniProtKB {GO:0005886=PMID:8508762, GO:0005911=PMID:8508762, GO:0005887=PMID:8508762, GO:0005509=GO_REF:0000002, GO:0007267=PMID:8508762, GO:0016021=GO_REF:0000038, GO:0007156=GO_REF:0000002, GO:0007399=PMID:8508762} Q08174 Protocadherin-1 protein 20030904 {GO:0005886=TAS, GO:0005911=TAS, GO:0005887=TAS, GO:0005509=IEA, GO:0007267=TAS, GO:0016021=IEA, GO:0007156=IEA, GO:0007399=TAS} cell-cell signaling, homophilic cell adhesion, nervous system development cell-cell junction, integral to membrane, integral to plasma membrane, plasma membrane calcium ion binding Human PCDH10 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000019} Q9P2E7 Protocadherin-10 protein 20130413 {GO:0005886=IEA, GO:0005509=IEA, GO:0016021=IEA, GO:0007156=IEA} homophilic cell adhesion integral to membrane, plasma membrane calcium ion binding Human UniProtKB-SubCell:SL-0039 PCDH11X PINC UniProtKB {GO:0005886=PMID:10644456, GO:0005887=PMID:10644456, GO:0010923=PMID:19389623, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000038, GO:0007156=GO_REF:0000002} Q9BZA7 Protocadherin-11 X-linked protein 20061106 {GO:0005886=TAS, GO:0005887=TAS, GO:0010923=IDA, GO:0005509=IEA, GO:0016021=IEA, GO:0007156=IEA} homophilic cell adhesion, negative regulation of phosphatase activity integral to membrane, integral to plasma membrane, plasma membrane calcium ion binding Human PCDH15 HGNC UniProtKB {GO:0005886=GO_REF:0000039, GO:0007605=PMID:11398101, GO:0005509=GO_REF:0000002, GO:0060088=GO_REF:0000019, GO:0045202=PMID:11487575, GO:0032420=PMID:14570705, GO:0005576=GO_REF:0000039, GO:0045494=PMID:11398101, GO:0035058=GO_REF:0000019, GO:0001964=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0035264=GO_REF:0000019, GO:0050910=GO_REF:0000019, GO:0050973=GO_REF:0000019, GO:0007628=GO_REF:0000019, GO:0050957=PMID:16679490, GO:0007015=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007601=GO_REF:0000019, GO:0007156=GO_REF:0000002, GO:0002009=GO_REF:0000019, GO:0050953=PMID:11398101, GO:0060013=GO_REF:0000019, GO:0001750=PMID:14570705} Q96QU1 Protocadherin-15 protein 20071018 {GO:0005886=IEA, GO:0007605=IMP, GO:0005509=IEA, GO:0060088=IEA, GO:0045202=IDA, GO:0032420=ISS, GO:0005576=IEA, GO:0045494=IMP, GO:0035058=IEA, GO:0001964=IEA, GO:0005737=IEA, GO:0035264=IEA, GO:0050910=IEA, GO:0050973=IEA, GO:0007628=IEA, GO:0050957=IMP, GO:0007015=IEA, GO:0016021=IEA, GO:0007601=IEA, GO:0007156=IEA, GO:0002009=IEA, GO:0050953=IMP, GO:0060013=IEA, GO:0001750=IDA} actin filament organization, adult walking behavior, auditory receptor cell stereocilium organization, detection of mechanical stimulus involved in equilibrioception, detection of mechanical stimulus involved in sensory perception of sound, equilibrioception, homophilic cell adhesion, morphogenesis of an epithelium, multicellular organism growth, nonmotile primary cilium assembly, photoreceptor cell maintenance, righting reflex, sensory perception of light stimulus, sensory perception of sound, startle response, visual perception cytoplasm, extracellular region, integral to membrane, photoreceptor outer segment, plasma membrane, stereocilium, synapse calcium ion binding Human PCDH17 UniProtKB UniProtKB {GO:0005515=PMID:19945174, GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000002} O14917 Protocadherin-17 protein 20110208 {GO:0005515=IPI, GO:0005886=IEA, GO:0005509=IEA, GO:0016021=IEA, GO:0007156=IEA} homophilic cell adhesion integral to membrane, plasma membrane calcium ion binding, protein binding Human UniProtKB:P21754 PCDH18 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0007420=GO_REF:0000024, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000002} Q9HCL0 Protocadherin-18 protein 20041006 {GO:0005886=IEA, GO:0007420=ISS, GO:0005509=IEA, GO:0016021=IEA, GO:0007156=IEA} brain development, homophilic cell adhesion integral to membrane, plasma membrane calcium ion binding Human UniProtKB:Q8VHR0 PCDH19 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000002} Q8TAB3 Protocadherin-19 protein 20130413 {GO:0005886=IEA, GO:0005509=IEA, GO:0016021=IEA, GO:0007156=IEA} homophilic cell adhesion integral to membrane, plasma membrane calcium ion binding Human UniProtKB-SubCell:SL-0039 PCDH20 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000002} Q8N6Y1 Protocadherin-20 protein 20130413 {GO:0005886=IEA, GO:0005509=IEA, GO:0016021=IEA, GO:0007156=IEA} homophilic cell adhesion integral to membrane, plasma membrane calcium ion binding Human UniProtKB-SubCell:SL-0039 PCDH7 PINC UniProtKB {GO:0005886=PMID:9615233, GO:0005887=PMID:9615233, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000038, GO:0007156=GO_REF:0000002} O60245 Protocadherin-7 protein 20030904 {GO:0005886=TAS, GO:0005887=TAS, GO:0005509=IEA, GO:0016021=IEA, GO:0007156=IEA} homophilic cell adhesion integral to membrane, integral to plasma membrane, plasma membrane calcium ion binding Human PCDH8 PINC UniProtKB {GO:0042734=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0005886=PMID:9787079, GO:0016331=GO_REF:0000019, GO:0005887=PMID:9787079, GO:0045211=GO_REF:0000039, GO:0001756=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0007267=PMID:9787079, GO:0007268=GO_REF:0000019, GO:0007156=GO_REF:0000002, GO:0030425=GO_REF:0000039} O95206 Protocadherin-8 protein 20030904 {GO:0042734=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0016331=IEA, GO:0005887=TAS, GO:0045211=IEA, GO:0001756=IEA, GO:0005509=IEA, GO:0007267=TAS, GO:0007268=IEA, GO:0007156=IEA, GO:0030425=IEA} cell-cell signaling, homophilic cell adhesion, morphogenesis of embryonic epithelium, somitogenesis, synaptic transmission cell junction, dendrite, integral to plasma membrane, plasma membrane, postsynaptic membrane, presynaptic membrane calcium ion binding Human PCDH9 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007156=GO_REF:0000002} Q9HC56 Protocadherin-9 protein 20130413 {GO:0005886=IEA, GO:0005509=IEA, GO:0016021=IEA, GO:0007156=IEA} homophilic cell adhesion integral to membrane, plasma membrane calcium ion binding Human UniProtKB-SubCell:SL-0039 PCF11 Reactome UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0006379=PMID:11060040, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0006366=Reactome:REACT_1366, GO:0000398=Reactome:REACT_467, GO:0031124=Reactome:REACT_1849, GO:0005654=Reactome:REACT_1935, GO:0005849=PMID:11060040} O94913 Pre-mRNA cleavage complex 2 protein Pcf11 protein 20130213 {GO:0008380=TAS, GO:0006379=NAS, GO:0010467=TAS, GO:0006369=TAS, GO:0006366=TAS, GO:0000398=TAS, GO:0031124=TAS, GO:0005654=TAS, GO:0005849=NAS} RNA splicing, gene expression, mRNA 3'-end processing, mRNA cleavage, mRNA splicing, via spliceosome, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter mRNA cleavage factor complex, nucleoplasm Human PCGF1 HPA UniProtKB {GO:0005515=PMID:22493164, GO:0031519=PMID:16943429, GO:0035518=PMID:16943429, GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0008022=PMID:16943429, GO:0006351=GO_REF:0000037} Q9BSM1 Polycomb group RING finger protein 1 protein 20081203 {GO:0005515=IPI, GO:0031519=IDA, GO:0035518=IDA, GO:0006355=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0008022=IPI, GO:0006351=IEA} histone H2A monoubiquitination, regulation of transcription, DNA-dependent, transcription, DNA-dependent PcG protein complex, nucleolus, nucleus protein C-terminus binding, protein binding, zinc ion binding NOT Human PCGF2 IntAct UniProtKB {GO:0005515=PMID:22493164, GO:0031519=PMID:21282530, GO:0035102=PMID:19636380, GO:0000790=PMID:19636380, GO:0004842=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0003700=PMID:8325509, GO:0016573=GO_REF:0000019, GO:0005634=PMID:21282530, GO:0048704=GO_REF:0000019, GO:0000122=PMID:19636380, GO:0009952=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0001739=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0016604=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0008270=GO_REF:0000002} P35227 Polycomb group RING finger protein 2 protein 20130415 {GO:0005515=IPI, GO:0031519=IDA, GO:0035102=IDA, GO:0000790=IDA, GO:0004842=IEA, GO:0043066=IEA, GO:0003700=TAS, GO:0016573=IEA, GO:0005634=IDA, GO:0048704=IEA, GO:0000122=IMP, GO:0009952=IEA, GO:0001701=IEA, GO:0001739=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0016604=IEA, GO:0003682=IEA, GO:0008270=IEA} anterior/posterior pattern specification, embryonic skeletal system morphogenesis, histone acetylation, in utero embryonic development, negative regulation of apoptotic process, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent PRC1 complex, PcG protein complex, nuclear body, nuclear chromatin, nucleus, sex chromatin DNA binding, chromatin binding, protein binding, sequence-specific DNA binding transcription factor activity, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q99496 PCGF3 IntAct UniProtKB {GO:0005515=PMID:22493164, GO:0031519=PMID:21282530, GO:0006355=GO_REF:0000037, GO:0005634=PMID:21282530, GO:0008270=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q3KNV8 Polycomb group RING finger protein 3 protein 20130415 {GO:0005515=IPI, GO:0031519=IDA, GO:0006355=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent PcG protein complex, nucleus protein binding, zinc ion binding Human UniProtKB:Q99496 PCGF5 IntAct UniProtKB {GO:0005515=PMID:22493164, GO:0031519=PMID:21282530, GO:0005813=GO_REF:0000054, GO:0006355=GO_REF:0000037, GO:0005634=PMID:21282530, GO:0008270=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q86SE9 Polycomb group RING finger protein 5 protein 20130415 {GO:0005515=IPI, GO:0031519=IDA, GO:0005813=IDA, GO:0006355=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent PcG protein complex, centrosome, nucleus protein binding, zinc ion binding Human UniProtKB:Q99496 PCGF6 IntAct UniProtKB {GO:0005515=PMID:21282530, GO:0035102=PMID:19636380, GO:0031519=PMID:21282530, GO:0003700=PMID:8521824, GO:0005634=PMID:21282530, GO:0008270=GO_REF:0000002, GO:0003677=PMID:8521824, GO:0045892=PMID:8521824, GO:0006351=GO_REF:0000037} Q9BYE7 Polycomb group RING finger protein 6 protein 20130415 {GO:0005515=IPI, GO:0035102=IDA, GO:0031519=IDA, GO:0003700=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003677=IDA, GO:0045892=IDA, GO:0006351=IEA} negative regulation of transcription, DNA-dependent, transcription, DNA-dependent PRC1 complex, PcG protein complex, nucleus DNA binding, protein binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB:O00257-3 PCID2 UniProtKB UniProtKB {GO:0043488=PMID:20870947, GO:0043066=PMID:20870947, GO:0045579=GO_REF:0000019, GO:0090267=PMID:20870947, GO:2000117=PMID:20870947, GO:0005575=GO_REF:0000015, GO:0048536=GO_REF:0000024, GO:0045893=PMID:20870947} Q5JVF3 PCI domain-containing protein 2 protein 20101005 {GO:0043488=IMP, GO:0043066=IMP, GO:0045579=IEA, GO:0090267=IMP, GO:2000117=IMP, GO:0005575=ND, GO:0048536=ISS, GO:0045893=IMP} negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity, positive regulation of B cell differentiation, positive regulation of mitotic cell cycle spindle assembly checkpoint, positive regulation of transcription, DNA-dependent, regulation of mRNA stability, spleen development cellular_component Human PCIF1 HPA UniProtKB {GO:0005825=GO_REF:0000052, GO:0010923=PMID:19389623, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0015629=GO_REF:0000052} Q9H4Z3 Phosphorylated CTD-interacting factor 1 protein 20120912 {GO:0005825=IDA, GO:0010923=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0015629=IDA} negative regulation of phosphatase activity actin cytoskeleton, half bridge of spindle pole body, nucleolus, nucleus Human PCK1 BHF-UCL UniProtKB {GO:0031406=PMID:11851336, GO:0032868=PMID:14764811, GO:0014823=GO_REF:0000019, GO:0030145=PMID:11851336, GO:0000287=PMID:11851336, GO:0017144=Reactome:REACT_121388, GO:0005975=Reactome:REACT_474, GO:0006094=GO_REF:0000024, GO:0006107=GO_REF:0000019, GO:0042593=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0005525=PMID:11851336, GO:0005829=Reactome:REACT_27194, GO:0046327=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0004611=GO_REF:0000002, GO:0016301=GO_REF:0000038, GO:0004613=GO_REF:0000024, GO:0006006=PMID:14764811, GO:0019003=GO_REF:0000019, GO:0006475=PMID:20167786} P35558 "Phosphoenolpyruvate carboxykinase, cytosolic ""GTP""" protein 20080424 {GO:0031406=IDA, GO:0032868=IDA, GO:0014823=IEA, GO:0030145=IDA, GO:0000287=IDA, GO:0017144=TAS, GO:0005975=TAS, GO:0006094=ISS, GO:0006107=IEA, GO:0042593=ISS, GO:0044281=TAS, GO:0005525=IDA, GO:0005829=TAS, GO:0046327=ISS, GO:0005737=ISS, GO:0004611=IEA, GO:0016301=IEA, GO:0004613=ISS, GO:0006006=IMP, GO:0019003=IEA, GO:0006475=IDA} carbohydrate metabolic process, drug metabolic process, gluconeogenesis, glucose homeostasis, glucose metabolic process, glycerol biosynthetic process from pyruvate, internal protein amino acid acetylation, oxaloacetate metabolic process, response to activity, response to insulin stimulus, small molecule metabolic process cytoplasm, cytosol GDP binding, GTP binding, carboxylic acid binding, kinase activity, magnesium ion binding, manganese ion binding, phosphoenolpyruvate carboxykinase (GTP) activity, phosphoenolpyruvate carboxykinase activity Human UniProtKB:P07379 PCK2 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0005739=PMID:8645161, GO:0004611=PMID:8645161, GO:0005975=Reactome:REACT_474, GO:0016301=GO_REF:0000038, GO:0005759=Reactome:REACT_14793, GO:0004613=GO_REF:0000003, GO:0006094=Reactome:REACT_1520, GO:0006006=Reactome:REACT_723, GO:0044281=Reactome:REACT_111217, GO:0005525=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q16822 "Phosphoenolpyruvate carboxykinase ""GTP"", mitochondrial" protein 20130415 {GO:0005515=IPI, GO:0005739=TAS, GO:0004611=TAS, GO:0005975=TAS, GO:0016301=IEA, GO:0005759=TAS, GO:0004613=IEA, GO:0006094=TAS, GO:0006006=TAS, GO:0044281=TAS, GO:0005525=IEA, GO:0046872=IEA} carbohydrate metabolic process, gluconeogenesis, glucose metabolic process, small molecule metabolic process mitochondrial matrix, mitochondrion GTP binding, kinase activity, metal ion binding, phosphoenolpyruvate carboxykinase (GTP) activity, phosphoenolpyruvate carboxykinase activity, protein binding Human UniProtKB:P84022 PCLO UniProtKB UniProtKB {GO:0005215=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005509=GO_REF:0000024, GO:0045202=GO_REF:0000024, GO:0016079=PMID:10508862, GO:0008021=GO_REF:0000002, GO:0005544=GO_REF:0000024, GO:0016020=GO_REF:0000002, GO:0017157=GO_REF:0000019, GO:0019933=GO_REF:0000019, GO:0007010=GO_REF:0000024, GO:0005856=PMID:10508862, GO:0030073=GO_REF:0000019, GO:0005522=GO_REF:0000024} Q9Y6V0 Protein piccolo protein 20021105 {GO:0005215=IEA, GO:0030054=IEA, GO:0005509=ISS, GO:0045202=ISS, GO:0016079=NAS, GO:0008021=IEA, GO:0005544=ISS, GO:0016020=IEA, GO:0017157=IEA, GO:0019933=IEA, GO:0007010=ISS, GO:0005856=NAS, GO:0030073=IEA, GO:0005522=ISS} cAMP-mediated signaling, cytoskeleton organization, insulin secretion, regulation of exocytosis, synaptic vesicle exocytosis cell junction, cytoskeleton, membrane, synapse, synaptic vesicle calcium ion binding, calcium-dependent phospholipid binding, profilin binding, transporter activity Human PCM1 BHF-UCL UniProtKB {GO:0097150=GO_REF:0000019, GO:0005515=PMID:17574030, GO:0005813=GO_REF:0000052, GO:0031965=GO_REF:0000052, GO:0034453=GO_REF:0000024, GO:0034451=PMID:17574030, GO:0031513=PMID:17574030, GO:0042802=GO_REF:0000024, GO:0005829=Reactome:REACT_15470, GO:0051297=PMID:17574030, GO:0042384=PMID:17574030, GO:0005737=GO_REF:0000052, GO:0050768=GO_REF:0000024, GO:0000086=Reactome:REACT_2203, GO:0022027=GO_REF:0000024, GO:0071539=GO_REF:0000024, GO:0000278=Reactome:REACT_152, GO:0034454=GO_REF:0000019, GO:0000242=GO_REF:0000024} Q15154 Pericentriolar material 1 protein protein 20100310 {GO:0097150=IEA, GO:0005515=IPI, GO:0005813=IDA, GO:0031965=IDA, GO:0034453=ISS, GO:0034451=IDA, GO:0031513=IDA, GO:0042802=ISS, GO:0005829=TAS, GO:0051297=IMP, GO:0042384=IMP, GO:0005737=IDA, GO:0050768=ISS, GO:0000086=TAS, GO:0022027=ISS, GO:0071539=ISS, GO:0000278=TAS, GO:0034454=IEA, GO:0000242=ISS} G2/M transition of mitotic cell cycle, centrosome organization, cilium assembly, interkinetic nuclear migration, microtubule anchoring, microtubule anchoring at centrosome, mitotic cell cycle, negative regulation of neurogenesis, neuronal stem cell maintenance, protein localization to centrosome centriolar satellite, centrosome, cytoplasm, cytosol, nonmotile primary cilium, nuclear membrane, pericentriolar material identical protein binding, protein binding Human UniProtKB:Q9R0L6 PCMT1 HPA UniProtKB {GO:0004719=PMID:8074695, GO:0005737=GO_REF:0000052, GO:0005783=PMID:1339271, GO:0030091=PMID:8074695, GO:0006479=PMID:3355545, GO:0046500=GO_REF:0000019, GO:0046498=GO_REF:0000019} P22061 Protein-L-isoaspartate(D-aspartate) O-methyltransferase protein 20080205 {GO:0004719=TAS, GO:0005737=IDA, GO:0005783=TAS, GO:0030091=TAS, GO:0006479=TAS, GO:0046500=IEA, GO:0046498=IEA} S-adenosylhomocysteine metabolic process, S-adenosylmethionine metabolic process, protein methylation, protein repair cytoplasm, endoplasmic reticulum protein-L-isoaspartate (D-aspartate) O-methyltransferase activity Human PCMTD1 UniProtKB UniProtKB {GO:0004719=GO_REF:0000002, GO:0005737=GO_REF:0000039} Q96MG8 Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 protein 20130413 {GO:0004719=IEA, GO:0005737=IEA} cytoplasm protein-L-isoaspartate (D-aspartate) O-methyltransferase activity Human UniProtKB-SubCell:SL-0086 PCMTD2 UniProtKB UniProtKB {GO:0004719=GO_REF:0000002, GO:0005737=GO_REF:0000039} Q9NV79 Protein-L-isoaspartate O-methyltransferase domain-containing protein 2 protein 20130413 {GO:0004719=IEA, GO:0005737=IEA} cytoplasm protein-L-isoaspartate (D-aspartate) O-methyltransferase activity Human UniProtKB-SubCell:SL-0086 PCNA HPA UniProtKB {GO:0005515=PMID:15543136, GO:0043626=GO_REF:0000002, GO:0032405=PMID:11005803, GO:0008283=PMID:2565339, GO:0033993=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0032077=PMID:19443450, GO:0019985=PMID:20129063, GO:0007507=GO_REF:0000019, GO:0000084=Reactome:REACT_899, GO:0005737=GO_REF:0000052, GO:0006271=Reactome:REACT_932, GO:0000082=Reactome:REACT_1783, GO:0000083=Reactome:REACT_683, GO:0000723=Reactome:REACT_7970, GO:0015630=GO_REF:0000052, GO:0000722=Reactome:REACT_8027, GO:0070557=PMID:18794347, GO:0006297=Reactome:REACT_1998, GO:0005663=PMID:2565339, GO:0006298=PMID:11005803, GO:0043596=PMID:15543136, GO:0006275=GO_REF:0000002, GO:0030971=PMID:17115032, GO:0048015=PMID:15504738, GO:0000701=PMID:11005803, GO:0005730=GO_REF:0000052, GO:0030337=GO_REF:0000002, GO:0006260=PMID:15504738, GO:0006281=Reactome:REACT_216, GO:0006283=Reactome:REACT_1628, GO:0006284=Reactome:REACT_1104, GO:0032139=PMID:11005803, GO:0005654=Reactome:REACT_111167, GO:0006289=Reactome:REACT_1826, GO:0000278=Reactome:REACT_152, GO:0032201=Reactome:REACT_7961, GO:0046686=GO_REF:0000019} P12004 Proliferating cell nuclear antigen protein 20101115 {GO:0005515=IPI, GO:0043626=IEA, GO:0032405=IDA, GO:0008283=TAS, GO:0033993=IEA, GO:0005634=IDA, GO:0032077=IDA, GO:0019985=IDA, GO:0007507=IEA, GO:0000084=TAS, GO:0005737=IDA, GO:0006271=TAS, GO:0000082=TAS, GO:0000083=TAS, GO:0000723=TAS, GO:0015630=IDA, GO:0000722=TAS, GO:0070557=IDA, GO:0006297=TAS, GO:0005663=TAS, GO:0006298=IDA, GO:0043596=IDA, GO:0006275=IEA, GO:0030971=IPI, GO:0048015=NAS, GO:0000701=IDA, GO:0005730=IDA, GO:0030337=IEA, GO:0006260=NAS, GO:0006281=TAS, GO:0006283=TAS, GO:0006284=TAS, GO:0032139=IDA, GO:0005654=TAS, GO:0006289=TAS, GO:0000278=TAS, GO:0032201=TAS, GO:0046686=IEA} DNA repair, DNA replication, DNA strand elongation involved in DNA replication, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, base-excision repair, cell proliferation, heart development, mismatch repair, mitotic cell cycle, nucleotide-excision repair, nucleotide-excision repair, DNA gap filling, phosphatidylinositol-mediated signaling, positive regulation of deoxyribonuclease activity, regulation of DNA replication, regulation of transcription involved in G1/S phase of mitotic cell cycle, response to cadmium ion, response to lipid, telomere maintenance, telomere maintenance via recombination, telomere maintenance via semi-conservative replication, transcription-coupled nucleotide-excision repair, translesion synthesis DNA replication factor C complex, PCNA complex, PCNA-p21 complex, cytoplasm, microtubule cytoskeleton, nuclear replication fork, nucleolus, nucleoplasm, nucleus DNA polymerase processivity factor activity, MutLalpha complex binding, dinucleotide insertion or deletion binding, protein binding, purine-specific mismatch base pair DNA N-glycosylase activity, receptor tyrosine kinase binding Human PCNP HGNC UniProtKB {GO:0005515=PMID:12176013, GO:0007049=GO_REF:0000037, GO:0016567=PMID:14741369, GO:0043161=PMID:14741369, GO:0005634=PMID:12176013} Q8WW12 PEST proteolytic signal-containing nuclear protein protein 20060306 {GO:0005515=IPI, GO:0007049=IEA, GO:0016567=IDA, GO:0043161=IDA, GO:0005634=IDA} cell cycle, proteasomal ubiquitin-dependent protein catabolic process, protein ubiquitination nucleus protein binding Human PCNT HPA UniProtKB {GO:0005515=PMID:20466722, GO:0005516=GO_REF:0000037, GO:0005813=GO_REF:0000052, GO:0005814=GO_REF:0000019, GO:0021696=GO_REF:0000019, GO:0005874=GO_REF:0000037, GO:0000226=PMID:18955030, GO:0006915=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0005829=Reactome:REACT_15470, GO:0045171=GO_REF:0000019, GO:0048854=GO_REF:0000019, GO:0061351=GO_REF:0000019, GO:0042384=PMID:15337773, GO:0005737=GO_REF:0000052, GO:0021772=GO_REF:0000019, GO:0035264=GO_REF:0000019, GO:0000086=Reactome:REACT_2203, GO:0007051=GO_REF:0000019, GO:0000278=Reactome:REACT_152, GO:0001764=GO_REF:0000019, GO:0035108=GO_REF:0000019} O95613 Pericentrin protein 20100326 {GO:0005515=IPI, GO:0005516=IEA, GO:0005813=IDA, GO:0005814=IEA, GO:0021696=IEA, GO:0005874=IEA, GO:0000226=IMP, GO:0006915=IEA, GO:0001701=IEA, GO:0005829=TAS, GO:0045171=IEA, GO:0048854=IEA, GO:0061351=IEA, GO:0042384=IDA, GO:0005737=IDA, GO:0021772=IEA, GO:0035264=IEA, GO:0000086=TAS, GO:0007051=IEA, GO:0000278=TAS, GO:0001764=IEA, GO:0035108=IEA} G2/M transition of mitotic cell cycle, apoptotic process, brain morphogenesis, cerebellar cortex morphogenesis, cilium assembly, in utero embryonic development, limb morphogenesis, microtubule cytoskeleton organization, mitotic cell cycle, multicellular organism growth, neural precursor cell proliferation, neuron migration, olfactory bulb development, spindle organization centriole, centrosome, cytoplasm, cytosol, intercellular bridge, microtubule calmodulin binding, protein binding Human PCNX UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q96RV3 Pecanex-like protein 1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 PCNXL3 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9H6A9 Pecanex-like protein 3 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 PCOLCE GOC UniProtKB {GO:0016504=PMID:12393877, GO:0010952=PMID:12393877, GO:0005518=PMID:12393877, GO:0006508=GO_REF:0000019, GO:0007275=PMID:7523404, GO:0008201=PMID:12393877} Q15113 Procollagen C-endopeptidase enhancer 1 protein 20130413 {GO:0016504=IDA, GO:0010952=IDA, GO:0005518=IDA, GO:0006508=IEA, GO:0007275=TAS, GO:0008201=IDA} multicellular organismal development, positive regulation of peptidase activity, proteolysis collagen binding, heparin binding, peptidase activator activity Human PCP4 PINC UniProtKB {GO:0005516=GO_REF:0000019, GO:0005634=PMID:16780588, GO:0007417=PMID:8914602, GO:0005829=PMID:16780588} P48539 Purkinje cell protein 4 protein 20030904 {GO:0005516=IEA, GO:0005634=IDA, GO:0007417=TAS, GO:0005829=IDA} central nervous system development cytosol, nucleus calmodulin binding Human PCP4L1 null null {} null null null null {} null null null PCSK1 BHF-UCL UniProtKB {GO:0030133=GO_REF:0000039, GO:0005794=GO_REF:0000033, GO:0050796=Reactome:REACT_23974, GO:0016486=Reactome:REACT_15452, GO:0004252=GO_REF:0000024, GO:0008152=PMID:9207799, GO:0043043=GO_REF:0000024, GO:0007267=PMID:9207799, GO:0006508=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0005615=PMID:8397508, GO:0034774=Reactome:REACT_19170} P29120 Neuroendocrine convertase 1 protein 20080130 {GO:0030133=IEA, GO:0005794=IBA, GO:0050796=TAS, GO:0016486=TAS, GO:0004252=ISS, GO:0008152=TAS, GO:0043043=ISS, GO:0007267=TAS, GO:0006508=IEA, GO:0044267=TAS, GO:0005615=IDA, GO:0034774=TAS} cell-cell signaling, cellular protein metabolic process, metabolic process, peptide biosynthetic process, peptide hormone processing, proteolysis, regulation of insulin secretion Golgi apparatus, extracellular space, secretory granule lumen, transport vesicle serine-type endopeptidase activity Human UniProtKB:P63239 PCSK1N GOC UniProtKB {GO:0010951=PMID:10632593, GO:0005802=GO_REF:0000019, GO:0005794=GO_REF:0000039, GO:0004866=PMID:10632593, GO:0016486=GO_REF:0000019, GO:0004867=GO_REF:0000019, GO:0007218=GO_REF:0000037, GO:0009409=GO_REF:0000019, GO:0005102=PMID:10632593, GO:0030141=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0002021=GO_REF:0000019} Q9UHG2 ProSAAS protein 20130413 {GO:0010951=TAS, GO:0005802=IEA, GO:0005794=IEA, GO:0004866=TAS, GO:0016486=IEA, GO:0004867=IEA, GO:0007218=IEA, GO:0009409=IEA, GO:0005102=TAS, GO:0030141=IEA, GO:0005615=IEA, GO:0002021=IEA} negative regulation of endopeptidase activity, neuropeptide signaling pathway, peptide hormone processing, response to cold, response to dietary excess Golgi apparatus, extracellular space, secretory granule, trans-Golgi network endopeptidase inhibitor activity, receptor binding, serine-type endopeptidase inhibitor activity Human PCSK2 BHF-UCL UniProtKB {GO:0030133=GO_REF:0000039, GO:0005515=PMID:7913882, GO:0016540=GO_REF:0000019, GO:0004252=PMID:7626024, GO:0009790=GO_REF:0000019, GO:0005615=PMID:9020868, GO:0032403=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0007399=GO_REF:0000019, GO:0034230=GO_REF:0000024, GO:0034231=GO_REF:0000024, GO:0016020=PMID:8034613, GO:0006508=PMID:7626024, GO:0043204=GO_REF:0000019, GO:0030070=PMID:7626024, GO:0044267=Reactome:REACT_17015, GO:0034774=Reactome:REACT_15374} P16519 Neuroendocrine convertase 2 protein 20080131 {GO:0030133=IEA, GO:0005515=IPI, GO:0016540=IEA, GO:0004252=IDA, GO:0009790=IEA, GO:0005615=IDA, GO:0032403=IEA, GO:0030425=IEA, GO:0007399=IEA, GO:0034230=ISS, GO:0034231=ISS, GO:0016020=IDA, GO:0006508=IDA, GO:0043204=IEA, GO:0030070=IDA, GO:0044267=TAS, GO:0034774=TAS} cellular protein metabolic process, embryo development, enkephalin processing, insulin processing, islet amyloid polypeptide processing, nervous system development, protein autoprocessing, proteolysis dendrite, extracellular space, membrane, perikaryon, secretory granule lumen, transport vesicle protein binding, protein complex binding, serine-type endopeptidase activity Human PCSK4 RefGenome UniProtKB {GO:0004252=GO_REF:0000033, GO:0006508=GO_REF:0000033, GO:0007340=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007339=GO_REF:0000019, GO:0048240=GO_REF:0000019, GO:0002080=GO_REF:0000019} Q6UW60 Proprotein convertase subtilisin/kexin type 4 protein 20110201 {GO:0004252=IBA, GO:0006508=IBA, GO:0007340=IEA, GO:0016021=IEA, GO:0007339=IEA, GO:0048240=IEA, GO:0002080=IEA} acrosome reaction, binding of sperm to zona pellucida, proteolysis, sperm capacitation acrosomal membrane, integral to membrane serine-type endopeptidase activity Human PANTHER:PTN000083353 PCSK5 BHF-UCL UniProtKB {GO:0032455=Reactome:REACT_11062, GO:0004252=PMID:8901832, GO:0002001=PMID:8901832, GO:0030323=PMID:8940009, GO:0007267=PMID:8901832, GO:0048706=PMID:8940009, GO:0042089=PMID:8940009, GO:0009952=PMID:18519639, GO:0005615=PMID:8940009, GO:0007507=PMID:8940009, GO:0016486=PMID:8901832, GO:0016485=PMID:8901832, GO:0006508=GO_REF:0000037, GO:0030141=GO_REF:0000024, GO:0035108=PMID:8940009, GO:0042277=PMID:8940009, GO:0048011=Reactome:REACT_11061, GO:0005794=GO_REF:0000024, GO:0019067=PMID:8940009, GO:0001822=PMID:8940009, GO:0005796=Reactome:REACT_10058, GO:0007566=PMID:8940009, GO:0043043=PMID:8901832, GO:0048566=PMID:8940009, GO:0012505=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0006465=PMID:16912035} Q92824 Proprotein convertase subtilisin/kexin type 5 protein 20080616 {GO:0032455=TAS, GO:0004252=IDA, GO:0002001=IEP, GO:0030323=ISS, GO:0007267=TAS, GO:0048706=ISS, GO:0042089=ISS, GO:0009952=IMP, GO:0005615=ISS, GO:0007507=ISS, GO:0016486=IDA, GO:0016485=IDA, GO:0006508=IEA, GO:0030141=ISS, GO:0035108=ISS, GO:0042277=ISS, GO:0048011=TAS, GO:0005794=ISS, GO:0019067=ISS, GO:0001822=ISS, GO:0005796=TAS, GO:0007566=ISS, GO:0043043=IDA, GO:0048566=ISS, GO:0012505=IEA, GO:0016021=IEA, GO:0006465=IDA} anterior/posterior pattern specification, cell-cell signaling, cytokine biosynthetic process, embryo implantation, embryonic digestive tract development, embryonic skeletal system development, heart development, kidney development, limb morphogenesis, nerve growth factor processing, neurotrophin TRK receptor signaling pathway, peptide biosynthetic process, peptide hormone processing, protein processing, proteolysis, renin secretion into blood stream, respiratory tube development, signal peptide processing, viral assembly, maturation, egress, and release Golgi apparatus, Golgi lumen, endomembrane system, extracellular space, integral to membrane, secretory granule peptide binding, serine-type endopeptidase activity Human UniProtKB:Q04592 PCSK6 BHF-UCL UniProtKB {GO:0032455=Reactome:REACT_11062, GO:0007368=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0043499=PMID:12535616, GO:0009986=PMID:12535616, GO:0048406=PMID:8615794, GO:0004252=PMID:8218226, GO:0007354=GO_REF:0000019, GO:0005783=GO_REF:0000039, GO:0005796=Reactome:REACT_10058, GO:0032902=PMID:8615794, GO:0005615=PMID:8906861, GO:0012505=GO_REF:0000039, GO:0031012=PMID:12535616, GO:0009100=PMID:8218226, GO:0004175=PMID:9242664, GO:0016486=PMID:9242664, GO:0016020=GO_REF:0000037, GO:0016485=PMID:9738469, GO:0006508=GO_REF:0000037, GO:0030510=PMID:10467177, GO:0008201=PMID:12535616, GO:0032940=PMID:8615794} P29122 Proprotein convertase subtilisin/kexin type 6 protein 20080424 {GO:0032455=TAS, GO:0007368=IEA, GO:0048011=TAS, GO:0043499=IDA, GO:0009986=IDA, GO:0048406=IDA, GO:0004252=IDA, GO:0007354=IEA, GO:0005783=IEA, GO:0005796=TAS, GO:0032902=IDA, GO:0005615=IDA, GO:0012505=IEA, GO:0031012=IDA, GO:0009100=IDA, GO:0004175=IDA, GO:0016486=IDA, GO:0016020=IEA, GO:0016485=IDA, GO:0006508=IEA, GO:0030510=TAS, GO:0008201=IDA, GO:0032940=IDA} determination of left/right symmetry, glycoprotein metabolic process, nerve growth factor processing, nerve growth factor production, neurotrophin TRK receptor signaling pathway, peptide hormone processing, protein processing, proteolysis, regulation of BMP signaling pathway, secretion by cell, zygotic determination of anterior/posterior axis, embryo Golgi lumen, cell surface, endomembrane system, endoplasmic reticulum, extracellular matrix, extracellular space, membrane endopeptidase activity, eukaryotic cell surface binding, heparin binding, nerve growth factor binding, serine-type endopeptidase activity Human PCSK7 RefGenome UniProtKB {GO:0030173=PMID:9341152, GO:0016486=PMID:9341152, GO:0004252=GO_REF:0000033, GO:0006508=GO_REF:0000037} Q16549 Proprotein convertase subtilisin/kexin type 7 protein 20110201 {GO:0030173=IDA, GO:0016486=NAS, GO:0004252=IBA, GO:0006508=IEA} peptide hormone processing, proteolysis integral to Golgi membrane serine-type endopeptidase activity Human PANTHER:PTN000082845 PCSK9 BHF-UCL UniProtKB {GO:0005515=PMID:22493497, GO:0048471=PMID:18039658, GO:0016540=PMID:14622975, GO:0010469=PMID:17328821, GO:0004252=PMID:12552133, GO:0005783=PMID:17461796, GO:0070326=PMID:18039658, GO:0043621=PMID:18197702, GO:0005615=PMID:12552133, GO:0005764=PMID:18039658, GO:0042802=GO_REF:0000002, GO:0043523=GO_REF:0000024, GO:0005737=PMID:22580899, GO:0043525=PMID:17051583, GO:0030182=PMID:12552133, GO:0034190=PMID:18039658, GO:0006508=GO_REF:0000033, GO:0001920=PMID:17452316, GO:0010989=PMID:17328821, GO:0022008=PMID:12552133, GO:0009267=PMID:16407292, GO:0008203=GO_REF:0000019, GO:0042632=PMID:17170371, GO:0005791=GO_REF:0000019, GO:0032869=PMID:12552133, GO:0005794=PMID:17461796, GO:0009986=PMID:17461796, GO:0001822=PMID:12552133, GO:0005770=PMID:18039658, GO:0030169=GO_REF:0000024, GO:0006915=GO_REF:0000037, GO:0006917=GO_REF:0000019, GO:0031232=PMID:17328821, GO:0043086=GO_REF:0000002, GO:0001889=PMID:12552133, GO:0032803=GO_REF:0000019, GO:0019871=PMID:22493497, GO:0032802=PMID:16912035, GO:0042157=GO_REF:0000019, GO:0006641=GO_REF:0000019, GO:0007041=PMID:17452316, GO:0034185=GO_REF:0000024, GO:0006644=GO_REF:0000019, GO:0002092=PMID:17328821, GO:0005769=PMID:17461796, GO:0050750=PMID:17452316, GO:0034189=GO_REF:0000024} Q8NBP7 Proprotein convertase subtilisin/kexin type 9 protein 20090731 {GO:0005515=IPI, GO:0048471=IDA, GO:0016540=IDA, GO:0010469=IDA, GO:0004252=IDA, GO:0005783=IDA, GO:0070326=IDA, GO:0043621=IDA, GO:0005615=IDA, GO:0005764=IDA, GO:0042802=IEA, GO:0043523=ISS, GO:0005737=IDA, GO:0043525=IMP, GO:0030182=ISS, GO:0034190=IDA, GO:0006508=IBA, GO:0001920=IDA, GO:0010989=IDA, GO:0022008=ISS, GO:0009267=ISS, GO:0008203=IEA, GO:0042632=IMP, GO:0005791=IEA, GO:0032869=ISS, GO:0005794=IDA, GO:0009986=IDA, GO:0001822=ISS, GO:0005770=IDA, GO:0030169=ISS, GO:0006915=IEA, GO:0006917=IEA, GO:0031232=IC, GO:0043086=IEA, GO:0001889=ISS, GO:0032803=IEA, GO:0019871=IDA, GO:0032802=IDA, GO:0042157=IEA, GO:0006641=IEA, GO:0007041=IDA, GO:0034185=ISS, GO:0006644=IEA, GO:0002092=IDA, GO:0005769=IDA, GO:0050750=IPI, GO:0034189=ISS} apoptotic process, cellular response to insulin stimulus, cellular response to starvation, cholesterol homeostasis, cholesterol metabolic process, induction of apoptosis, kidney development, lipoprotein metabolic process, liver development, low-density lipoprotein particle receptor catabolic process, lysosomal transport, negative regulation of catalytic activity, negative regulation of low-density lipoprotein particle clearance, negative regulation of receptor recycling, neurogenesis, neuron differentiation, phospholipid metabolic process, positive regulation of neuron apoptotic process, positive regulation of receptor internalization, protein autoprocessing, proteolysis, regulation of low-density lipoprotein particle receptor catabolic process, regulation of neuron apoptotic process, regulation of receptor activity, triglyceride metabolic process Golgi apparatus, cell surface, cytoplasm, early endosome, endoplasmic reticulum, extracellular space, extrinsic to external side of plasma membrane, late endosome, lysosome, perinuclear region of cytoplasm, rough endoplasmic reticulum apolipoprotein binding, apolipoprotein receptor binding, identical protein binding, low-density lipoprotein particle binding, low-density lipoprotein particle receptor binding, protein binding, protein self-association, serine-type endopeptidase activity, sodium channel inhibitor activity, very-low-density lipoprotein particle binding, very-low-density lipoprotein particle receptor binding Human GO:0002092 PCYOX1 BHF-UCL UniProtKB {GO:0034361=PMID:17154273, GO:0001735=PMID:10585463, GO:0005886=GO_REF:0000019, GO:0008555=GO_REF:0000019, GO:0030329=PMID:9287348, GO:0016670=GO_REF:0000002, GO:0030328=GO_REF:0000019, GO:0030327=PMID:10585463, GO:0005764=PMID:10585463} Q9UHG3 Prenylcysteine oxidase 1 protein 20090528 {GO:0034361=IDA, GO:0001735=IDA, GO:0005886=IEA, GO:0008555=IEA, GO:0030329=NAS, GO:0016670=IEA, GO:0030328=IEA, GO:0030327=IDA, GO:0005764=IDA} prenylated protein catabolic process, prenylcysteine catabolic process, prenylcysteine metabolic process lysosome, plasma membrane, very-low-density lipoprotein particle chloride-transporting ATPase activity, oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor, prenylcysteine oxidase activity Human PCYT1A Reactome UniProtKB {GO:0009058=GO_REF:0000002, GO:0016779=GO_REF:0000038, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0042803=GO_REF:0000019, GO:0008289=GO_REF:0000019, GO:0005829=GO_REF:0000039, GO:0042587=GO_REF:0000024, GO:0009628=GO_REF:0000019, GO:0005789=Reactome:REACT_121282, GO:0004105=GO_REF:0000024, GO:0006657=GO_REF:0000024, GO:0006644=Reactome:REACT_120870, GO:0046474=Reactome:REACT_121401, GO:0006656=Reactome:REACT_121238} P49585 Choline-phosphate cytidylyltransferase A protein 20111102 {GO:0009058=IEA, GO:0016779=IEA, GO:0044281=TAS, GO:0003824=IEA, GO:0042803=IEA, GO:0008289=IEA, GO:0005829=IEA, GO:0042587=ISS, GO:0009628=IEA, GO:0005789=TAS, GO:0004105=ISS, GO:0006657=ISS, GO:0006644=TAS, GO:0046474=TAS, GO:0006656=TAS} CDP-choline pathway, biosynthetic process, glycerophospholipid biosynthetic process, phosphatidylcholine biosynthetic process, phospholipid metabolic process, response to abiotic stimulus, small molecule metabolic process cytosol, endoplasmic reticulum membrane, glycogen granule catalytic activity, choline-phosphate cytidylyltransferase activity, lipid binding, nucleotidyltransferase activity, protein homodimerization activity Human PCYT1B GOC UniProtKB {GO:0005737=PMID:9593753, GO:0001541=GO_REF:0000019, GO:0009058=GO_REF:0000002, GO:0005789=Reactome:REACT_121282, GO:0004105=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0007283=GO_REF:0000019, GO:0006657=PMID:9593753, GO:0006644=Reactome:REACT_120870, GO:0003824=GO_REF:0000002, GO:0046474=Reactome:REACT_121401, GO:0006656=Reactome:REACT_121238} Q9Y5K3 Choline-phosphate cytidylyltransferase B protein 20130413 {GO:0005737=TAS, GO:0001541=IEA, GO:0009058=IEA, GO:0005789=TAS, GO:0004105=IEA, GO:0044281=TAS, GO:0007283=IEA, GO:0006657=TAS, GO:0006644=TAS, GO:0003824=IEA, GO:0046474=TAS, GO:0006656=TAS} CDP-choline pathway, biosynthetic process, glycerophospholipid biosynthetic process, ovarian follicle development, phosphatidylcholine biosynthetic process, phospholipid metabolic process, small molecule metabolic process, spermatogenesis cytoplasm, endoplasmic reticulum membrane catalytic activity, choline-phosphate cytidylyltransferase activity Human PCYT2 Reactome UniProtKB {GO:0006646=Reactome:REACT_120919, GO:0004306=Reactome:REACT_120845, GO:0009058=GO_REF:0000002, GO:0005789=Reactome:REACT_120845, GO:0016779=GO_REF:0000038, GO:0044281=Reactome:REACT_111217, GO:0005575=GO_REF:0000015, GO:0008654=PMID:9083101, GO:0006644=Reactome:REACT_120870, GO:0003824=GO_REF:0000002, GO:0046474=Reactome:REACT_121401} Q99447 Ethanolamine-phosphate cytidylyltransferase protein 20111102 {GO:0006646=TAS, GO:0004306=TAS, GO:0009058=IEA, GO:0005789=TAS, GO:0016779=IEA, GO:0044281=TAS, GO:0005575=ND, GO:0008654=TAS, GO:0006644=TAS, GO:0003824=IEA, GO:0046474=TAS} biosynthetic process, glycerophospholipid biosynthetic process, phosphatidylethanolamine biosynthetic process, phospholipid biosynthetic process, phospholipid metabolic process, small molecule metabolic process cellular_component, endoplasmic reticulum membrane catalytic activity, ethanolamine-phosphate cytidylyltransferase activity, nucleotidyltransferase activity Human PDAP1 PINC UniProtKB {GO:0007165=PMID:8780057, GO:0008283=PMID:8780057} Q13442 28 kDa heat- and acid-stable phosphoprotein protein 20030904 {GO:0007165=TAS, GO:0008283=TAS} cell proliferation, signal transduction Human PDC HPA UniProtKB {GO:0001917=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0004859=PMID:7961975, GO:0007186=PMID:7961975, GO:0005634=GO_REF:0000052, GO:0015629=GO_REF:0000052, GO:0007602=PMID:8288249, GO:0007601=GO_REF:0000037, GO:0005829=GO_REF:0000039, GO:0001750=GO_REF:0000039} P20941 Phosducin protein 20101115 {GO:0001917=IEA, GO:0005737=IDA, GO:0004859=TAS, GO:0007186=TAS, GO:0005634=IDA, GO:0015629=IDA, GO:0007602=TAS, GO:0007601=IEA, GO:0005829=IEA, GO:0001750=IEA} G-protein coupled receptor signaling pathway, phototransduction, visual perception actin cytoskeleton, cytoplasm, cytosol, nucleus, photoreceptor inner segment, photoreceptor outer segment phospholipase inhibitor activity Human PDCD1 GOC UniProtKB {GO:0005515=PMID:21982860, GO:0007165=PMID:1396582, GO:0005886=Reactome:REACT_19312, GO:0006959=PMID:9332365, GO:0031295=Reactome:REACT_19344, GO:0006915=GO_REF:0000037, GO:0007275=PMID:9332365, GO:0004871=PMID:1396582, GO:0016021=GO_REF:0000037, GO:0009897=GO_REF:0000019} Q15116 Programmed cell death protein 1 protein 20130413 {GO:0005515=IPI, GO:0007165=TAS, GO:0005886=TAS, GO:0006959=TAS, GO:0031295=TAS, GO:0006915=IEA, GO:0007275=TAS, GO:0004871=TAS, GO:0016021=IEA, GO:0009897=IEA} T cell costimulation, apoptotic process, humoral immune response, multicellular organismal development, signal transduction external side of plasma membrane, integral to membrane, plasma membrane protein binding, signal transducer activity Human PDCD10 IntAct UniProtKB {GO:0005515=PMID:23455922, GO:0008284=PMID:17360971, GO:0043066=PMID:17360971, GO:0047485=PMID:20489202, GO:0005886=GO_REF:0000039, GO:0000139=GO_REF:0000039, GO:0043406=PMID:17360971, GO:0006915=GO_REF:0000037, GO:0001525=GO_REF:0000037, GO:0042803=PMID:20489202, GO:0005829=PMID:20489202} Q9BUL8 Programmed cell death protein 10 protein 20130415 {GO:0005515=IPI, GO:0008284=IDA, GO:0043066=IDA, GO:0047485=IPI, GO:0005886=IEA, GO:0000139=IEA, GO:0043406=IDA, GO:0006915=IEA, GO:0001525=IEA, GO:0042803=IPI, GO:0005829=IDA} angiogenesis, apoptotic process, negative regulation of apoptotic process, positive regulation of MAP kinase activity, positive regulation of cell proliferation Golgi membrane, cytosol, plasma membrane protein N-terminus binding, protein binding, protein homodimerization activity Human UniProtKB:Q9Y6E0 PDCD11 IntAct UniProtKB {GO:0005515=PMID:14624448, GO:0006397=GO_REF:0000002, GO:0006364=GO_REF:0000037, GO:0003723=GO_REF:0000002, GO:0005730=GO_REF:0000039, GO:0005634=PMID:14624448, GO:0008134=PMID:14624448, GO:0005829=GO_REF:0000019} Q14690 Protein RRP5 homolog protein 20130415 {GO:0005515=IPI, GO:0006397=IEA, GO:0006364=IEA, GO:0003723=IEA, GO:0005730=IEA, GO:0005634=IDA, GO:0008134=IPI, GO:0005829=IEA} mRNA processing, rRNA processing cytosol, nucleolus, nucleus RNA binding, protein binding, transcription factor binding Human UniProtKB:P19838 PDCD2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000002, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0012501=GO_REF:0000019, GO:0003677=GO_REF:0000037} Q16342 Programmed cell death protein 2 protein 20130413 {GO:0005737=IEA, GO:0006915=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0012501=IEA, GO:0003677=IEA} apoptotic process, programmed cell death cytoplasm, nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 PDCD2L UniProtKB UniProtKB {GO:0007049=GO_REF:0000037, GO:0005737=GO_REF:0000002} Q9BRP1 Programmed cell death protein 2-like protein 20130413 {GO:0007049=IEA, GO:0005737=IEA} cell cycle cytoplasm Human UniProtKB-KW:KW-0131 PDCD4 HPA UniProtKB {GO:0005515=PMID:21163940, GO:0005737=PMID:16357133, GO:0016070=GO_REF:0000002, GO:0007569=PMID:12054647, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0006915=PMID:12054647, GO:0005634=GO_REF:0000052, GO:0043508=GO_REF:0000024, GO:0045786=PMID:12054647, GO:0045892=GO_REF:0000024, GO:0005829=PMID:12054647} Q5VZS7 Programmed cell death protein 4 protein 20101115 {GO:0005515=IPI, GO:0005737=IMP, GO:0016070=IEA, GO:0007569=IDA, GO:0003723=IEA, GO:0005730=IDA, GO:0006915=NAS, GO:0005634=IDA, GO:0043508=ISS, GO:0045786=NAS, GO:0045892=ISS, GO:0005829=IDA} RNA metabolic process, apoptotic process, cell aging, negative regulation of JUN kinase activity, negative regulation of cell cycle, negative regulation of transcription, DNA-dependent cytoplasm, cytosol, nucleolus, nucleus RNA binding, protein binding NOT Human PDCD5 InterPro UniProtKB {GO:0005737=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0006917=PMID:9920759, GO:0003677=GO_REF:0000002} Q3HM38 Programmed cell death 5 short isoform protein 20130413 {GO:0005737=IDA, GO:0006915=IEA, GO:0005634=IDA, GO:0006917=TAS, GO:0003677=IEA} apoptotic process, induction of apoptosis cytoplasm, nucleus DNA binding Human InterPro:IPR002836 PDCD6 ENSEMBL UniProtKB {GO:0005515=PMID:18256029, GO:0031965=GO_REF:0000039, GO:0006919=GO_REF:0000019, GO:0005783=PMID:17196169, GO:0005509=GO_REF:0000019, GO:0005634=PMID:21122810, GO:0033554=PMID:21122810, GO:0031410=PMID:21122810, GO:0097190=PMID:8560270, GO:0006886=PMID:21122810, GO:0042803=GO_REF:0000019, GO:0051592=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0060090=PMID:19520058, GO:0005789=GO_REF:0000039, GO:0046983=PMID:11883899, GO:0048306=GO_REF:0000019} Q86W51 Programmed cell death protein 6 protein 20130413 {GO:0005515=IPI, GO:0031965=IEA, GO:0006919=IEA, GO:0005783=IDA, GO:0005509=IEA, GO:0005634=IDA, GO:0033554=IDA, GO:0031410=IDA, GO:0097190=TAS, GO:0006886=IDA, GO:0042803=IEA, GO:0051592=IEA, GO:0005737=IEA, GO:0060090=IMP, GO:0005789=IEA, GO:0046983=IPI, GO:0048306=IEA} activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic signaling pathway, cellular response to stress, intracellular protein transport, response to calcium ion cytoplasm, cytoplasmic vesicle, endoplasmic reticulum, endoplasmic reticulum membrane, nuclear membrane, nucleus binding, bridging, calcium ion binding, calcium-dependent protein binding, protein binding, protein dimerization activity, protein homodimerization activity Human Ensembl:ENSMUSP00000022060 PDCD6IP HPA UniProtKB {GO:0005515=PMID:23088713, GO:0042470=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0007049=GO_REF:0000037, GO:0005815=GO_REF:0000039, GO:0019048=GO_REF:0000037, GO:0006915=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0048306=PMID:18256029, GO:0005829=GO_REF:0000039, GO:0051301=GO_REF:0000037} Q8WUM4 Programmed cell death 6-interacting protein protein 20081203 {GO:0005515=IPI, GO:0042470=IEA, GO:0005737=IDA, GO:0007049=IEA, GO:0005815=IEA, GO:0019048=IEA, GO:0006915=IEA, GO:0015031=IEA, GO:0048306=IPI, GO:0005829=IEA, GO:0051301=IEA} apoptotic process, cell cycle, cell division, protein transport, virus-host interaction cytoplasm, cytosol, melanosome, microtubule organizing center calcium-dependent protein binding, protein binding Human PDCD7 HGNC UniProtKB {GO:0008380=PMID:15146077, GO:0006915=GO_REF:0000019, GO:0051384=PMID:10037816, GO:0006917=PMID:10037816, GO:0005689=PMID:15146077} Q8N8D1 Programmed cell death protein 7 protein 20070418 {GO:0008380=IC, GO:0006915=IEA, GO:0051384=ISS, GO:0006917=ISS, GO:0005689=IDA} RNA splicing, apoptotic process, induction of apoptosis, response to glucocorticoid stimulus U12-type spliceosomal complex Human UniProtKB:Q9WTY1 PDCL UniProtKB UniProtKB {GO:0007165=PMID:10524200, GO:0006457=GO_REF:0000019, GO:0061084=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0007601=GO_REF:0000037} Q13371 Phosducin-like protein protein 20010917 {GO:0007165=NAS, GO:0006457=IEA, GO:0061084=IEA, GO:0032403=IEA, GO:0007601=IEA} negative regulation of protein refolding, protein folding, signal transduction, visual perception protein complex binding Human PDCL2 null null {} null null null null {} null null null PDCL3 HPA UniProtKB {GO:0005515=PMID:15371430, GO:0005737=GO_REF:0000052, GO:0019048=GO_REF:0000037, GO:0006915=GO_REF:0000037} Q9H2J4 Phosducin-like protein 3 protein 20101115 {GO:0005515=IPI, GO:0005737=IDA, GO:0019048=IEA, GO:0006915=IEA} apoptotic process, virus-host interaction cytoplasm protein binding Human PDDC1 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q8NB37 Parkinson disease 7 domain-containing protein 1 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 PDE10A Reactome UniProtKB {GO:0004118=PMID:19689430, GO:0004114=PMID:10373451, GO:0047555=GO_REF:0000003, GO:0010738=GO_REF:0000019, GO:0046069=GO_REF:0000041, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_23959, GO:0007165=GO_REF:0000002, GO:0030552=PMID:15938621, GO:0030553=PMID:15938621, GO:0043949=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0006198=GO_REF:0000041} Q9Y233 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A protein 20130301 {GO:0004118=IDA, GO:0004114=TAS, GO:0047555=IEA, GO:0010738=IEA, GO:0046069=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0007165=IEA, GO:0030552=NAS, GO:0030553=NAS, GO:0043949=IEA, GO:0007596=TAS, GO:0006198=IEA} blood coagulation, cAMP catabolic process, cGMP catabolic process, regulation of cAMP-mediated signaling, regulation of protein kinase A signaling cascade, signal transduction cytosol 3',5'-cyclic-GMP phosphodiesterase activity, 3',5'-cyclic-nucleotide phosphodiesterase activity, cAMP binding, cGMP binding, cGMP-stimulated cyclic-nucleotide phosphodiesterase activity, metal ion binding Human PDE12 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0016787=GO_REF:0000037} Q6L8Q7 2',5'-phosphodiesterase 12 protein 20130413 {GO:0005739=IEA, GO:0016787=IEA} mitochondrion hydrolase activity Human Ensembl:ENSMUSP00000059666 PDE1A Reactome UniProtKB {GO:0005516=GO_REF:0000037, GO:0007165=Reactome:REACT_12478, GO:0048011=Reactome:REACT_11061, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9470, GO:0007596=Reactome:REACT_604, GO:0004114=GO_REF:0000002, GO:0045087=Reactome:REACT_6802, GO:0004117=PMID:8557689, GO:0007202=Reactome:REACT_12079, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_23959} P54750 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A protein 20130213 {GO:0005516=IEA, GO:0007165=TAS, GO:0048011=TAS, GO:0007173=TAS, GO:0008543=TAS, GO:0007596=TAS, GO:0004114=IEA, GO:0045087=TAS, GO:0004117=TAS, GO:0007202=TAS, GO:0046872=IEA, GO:0005829=TAS} activation of phospholipase C activity, blood coagulation, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, neurotrophin TRK receptor signaling pathway, signal transduction cytosol 3',5'-cyclic-nucleotide phosphodiesterase activity, calmodulin binding, calmodulin-dependent cyclic-nucleotide phosphodiesterase activity, metal ion binding Human PDE1B HPA UniProtKB {GO:0005516=GO_REF:0000037, GO:0048101=GO_REF:0000019, GO:0004117=PMID:9419816, GO:0046069=PMID:14687666, GO:0005634=GO_REF:0000052, GO:0007202=Reactome:REACT_12079, GO:0042053=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_23959, GO:0005737=GO_REF:0000052, GO:0007173=Reactome:REACT_9417, GO:0043025=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0030224=PMID:14687666, GO:0097011=PMID:14687666, GO:0006198=PMID:14687666, GO:0048011=Reactome:REACT_11061, GO:0036006=PMID:14687666, GO:0004115=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0006915=PMID:8855339, GO:0042428=GO_REF:0000019, GO:0007165=Reactome:REACT_12478, GO:0001975=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0008542=GO_REF:0000019, GO:0001505=GO_REF:0000019} Q01064 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B protein 20090616 {GO:0005516=IEA, GO:0048101=IEA, GO:0004117=TAS, GO:0046069=IDA, GO:0005634=IDA, GO:0007202=TAS, GO:0042053=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0007173=TAS, GO:0043025=IEA, GO:0007626=IEA, GO:0030224=IEP, GO:0097011=IDA, GO:0006198=IDA, GO:0048011=TAS, GO:0036006=IDA, GO:0004115=IEA, GO:0005730=IDA, GO:0006915=TAS, GO:0042428=IEA, GO:0007165=TAS, GO:0001975=IEA, GO:0008543=TAS, GO:0007596=TAS, GO:0045087=TAS, GO:0008542=IEA, GO:0001505=IEA} activation of phospholipase C activity, apoptotic process, blood coagulation, cAMP catabolic process, cGMP catabolic process, cellular response to granulocyte macrophage colony-stimulating factor stimulus, cellular response to macrophage colony-stimulating factor stimulus, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, locomotory behavior, monocyte differentiation, neurotrophin TRK receptor signaling pathway, regulation of dopamine metabolic process, regulation of neurotransmitter levels, response to amphetamine, serotonin metabolic process, signal transduction, visual learning cytoplasm, cytosol, neuronal cell body, nucleolus, nucleus 3',5'-cyclic-AMP phosphodiesterase activity, calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity, calmodulin binding, calmodulin-dependent cyclic-nucleotide phosphodiesterase activity, metal ion binding Human PDE1C Reactome UniProtKB {GO:0007165=Reactome:REACT_12478, GO:0005516=GO_REF:0000037, GO:0048011=Reactome:REACT_11061, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0004117=PMID:8557689, GO:0007202=Reactome:REACT_12079, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_15450} Q14123 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C protein 20130213 {GO:0007165=TAS, GO:0005516=IEA, GO:0048011=TAS, GO:0007173=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0004117=TAS, GO:0007202=TAS, GO:0046872=IEA, GO:0005829=TAS} activation of phospholipase C activity, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, neurotrophin TRK receptor signaling pathway, signal transduction cytosol calmodulin binding, calmodulin-dependent cyclic-nucleotide phosphodiesterase activity, metal ion binding Human PDE2A UniProtKB UniProtKB {GO:0030424=GO_REF:0000019, GO:0048471=PMID:10375378, GO:0005886=PMID:19252089, GO:0005783=GO_REF:0000024, GO:0004118=PMID:17329248, GO:0030818=GO_REF:0000024, GO:0006626=GO_REF:0000024, GO:0071560=PMID:17704206, GO:0046069=PMID:15938621, GO:0005634=PMID:10375378, GO:0019934=PMID:17704206, GO:0030425=GO_REF:0000019, GO:0046872=GO_REF:0000038, GO:0042803=PMID:19828435, GO:0005829=Reactome:REACT_23959, GO:0005737=PMID:10375378, GO:0030552=PMID:15938621, GO:0030553=PMID:17329248, GO:0061028=GO_REF:0000024, GO:0008144=PMID:15938621, GO:0005759=GO_REF:0000024, GO:0033159=PMID:17329248, GO:0006198=PMID:19252089, GO:0030911=PMID:17329248, GO:0005262=PMID:10375378, GO:0036006=PMID:14687666, GO:0005794=GO_REF:0000024, GO:0004114=GO_REF:0000002, GO:0004112=PMID:15938621, GO:0000122=PMID:17329248, GO:0035690=PMID:15938621, GO:0042734=GO_REF:0000024, GO:0007165=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0008152=PMID:17329248, GO:0050729=GO_REF:0000024, GO:0019933=PMID:17704206, GO:0070588=PMID:10375378, GO:0071260=GO_REF:0000024, GO:0043117=PMID:17704206, GO:0043116=PMID:17704206, GO:0071321=PMID:17704206} Q6ZMR1 cGMP-dependent 3',5'-cyclic phosphodiesterase protein 20130413 {GO:0030424=IEA, GO:0048471=IDA, GO:0005886=IDA, GO:0005783=ISS, GO:0004118=IDA, GO:0030818=ISS, GO:0006626=ISS, GO:0071560=IEP, GO:0046069=IDA, GO:0005634=IDA, GO:0019934=IMP, GO:0030425=IEA, GO:0046872=IEA, GO:0042803=IPI, GO:0005829=TAS, GO:0005737=IDA, GO:0030552=IMP, GO:0030553=IDA, GO:0061028=ISS, GO:0008144=IPI, GO:0005759=ISS, GO:0033159=IDA, GO:0006198=IMP, GO:0030911=IPI, GO:0005262=TAS, GO:0036006=IDA, GO:0005794=ISS, GO:0004114=IEA, GO:0004112=IDA, GO:0000122=IDA, GO:0035690=IMP, GO:0042734=ISS, GO:0007165=IEA, GO:0007596=TAS, GO:0008152=IDA, GO:0050729=ISS, GO:0019933=IMP, GO:0070588=TAS, GO:0071260=ISS, GO:0043117=IMP, GO:0043116=IMP, GO:0071321=IDA} blood coagulation, cAMP catabolic process, cAMP-mediated signaling, cGMP catabolic process, cGMP-mediated signaling, calcium ion transmembrane transport, cellular response to cGMP, cellular response to drug, cellular response to macrophage colony-stimulating factor stimulus, cellular response to mechanical stimulus, cellular response to transforming growth factor beta stimulus, establishment of endothelial barrier, metabolic process, negative regulation of cAMP biosynthetic process, negative regulation of protein import into nucleus, translocation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of vascular permeability, positive regulation of inflammatory response, positive regulation of vascular permeability, protein targeting to mitochondrion, signal transduction Golgi apparatus, axon, cytoplasm, cytosol, dendrite, endoplasmic reticulum, mitochondrial matrix, nucleus, perinuclear region of cytoplasm, plasma membrane, presynaptic membrane 3',5'-cyclic-nucleotide phosphodiesterase activity, TPR domain binding, cAMP binding, cGMP binding, cGMP-stimulated cyclic-nucleotide phosphodiesterase activity, calcium channel activity, cyclic-nucleotide phosphodiesterase activity, drug binding, metal ion binding, protein homodimerization activity Human UniProtKB-KW:KW-0479 PDE3A Reactome UniProtKB {GO:0006629=PMID:8921398, GO:0043066=GO_REF:0000019, GO:0004115=GO_REF:0000019, GO:0004119=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0071560=PMID:17704206, GO:0019934=PMID:17704206, GO:0001556=GO_REF:0000019, GO:0051591=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_23959, GO:0040020=GO_REF:0000019, GO:0030552=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0060282=GO_REF:0000019, GO:0019933=PMID:17704206, GO:0016101=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0043117=PMID:17704206, GO:0043116=PMID:17704206, GO:0006198=PMID:19252089, GO:0071321=PMID:17704206} Q14432 cGMP-inhibited 3',5'-cyclic phosphodiesterase A protein 20130301 {GO:0006629=TAS, GO:0043066=IEA, GO:0004115=IEA, GO:0004119=IEA, GO:0042493=IEA, GO:0071560=IEP, GO:0019934=IMP, GO:0001556=IEA, GO:0051591=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0040020=IEA, GO:0030552=IEA, GO:0007596=TAS, GO:0060282=IEA, GO:0019933=IMP, GO:0016101=IEA, GO:0016021=IEA, GO:0043117=IMP, GO:0043116=IMP, GO:0006198=IMP, GO:0071321=IDA} blood coagulation, cAMP catabolic process, cAMP-mediated signaling, cGMP-mediated signaling, cellular response to cGMP, cellular response to transforming growth factor beta stimulus, diterpenoid metabolic process, lipid metabolic process, negative regulation of apoptotic process, negative regulation of vascular permeability, oocyte maturation, positive regulation of oocyte development, positive regulation of vascular permeability, regulation of meiosis, response to cAMP, response to drug cytosol, integral to membrane 3',5'-cyclic-AMP phosphodiesterase activity, cAMP binding, cGMP-inhibited cyclic-nucleotide phosphodiesterase activity, metal ion binding Human PDE3B BHF-UCL UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005515=PMID:17255105, GO:0033629=PMID:17884339, GO:0050995=PMID:11641262, GO:0004119=PMID:8884271, GO:0005783=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_23959, GO:0043951=PMID:17884339, GO:0006198=PMID:18586889, GO:0032045=PMID:17884339, GO:0032869=GO_REF:0000024, GO:0005794=GO_REF:0000024, GO:0004114=PMID:17884339, GO:0042593=GO_REF:0000019, GO:0001525=GO_REF:0000037, GO:0043422=GO_REF:0000024, GO:0007165=GO_REF:0000002, GO:0007162=PMID:17884339, GO:0050796=GO_REF:0000019, GO:0016020=PMID:18586889, GO:0007596=Reactome:REACT_604, GO:0031018=GO_REF:0000019, GO:0016525=PMID:21393242, GO:0016021=GO_REF:0000037} Q13370 cGMP-inhibited 3',5'-cyclic phosphodiesterase B protein 20090220 {GO:0008286=TAS, GO:0005515=IPI, GO:0033629=IC, GO:0050995=IMP, GO:0004119=TAS, GO:0005783=ISS, GO:0046872=IEA, GO:0005829=TAS, GO:0043951=IC, GO:0006198=IEP, GO:0032045=IDA, GO:0032869=ISS, GO:0005794=ISS, GO:0004114=TAS, GO:0042593=IEA, GO:0001525=IEA, GO:0043422=ISS, GO:0007165=IEA, GO:0007162=IMP, GO:0050796=IEA, GO:0016020=IDA, GO:0007596=TAS, GO:0031018=IEA, GO:0016525=IMP, GO:0016021=IEA} angiogenesis, blood coagulation, cAMP catabolic process, cellular response to insulin stimulus, endocrine pancreas development, glucose homeostasis, insulin receptor signaling pathway, negative regulation of angiogenesis, negative regulation of cAMP-mediated signaling, negative regulation of cell adhesion, negative regulation of cell adhesion mediated by integrin, negative regulation of lipid catabolic process, regulation of insulin secretion, signal transduction Golgi apparatus, cytosol, endoplasmic reticulum, guanyl-nucleotide exchange factor complex, integral to membrane, membrane 3',5'-cyclic-nucleotide phosphodiesterase activity, cGMP-inhibited cyclic-nucleotide phosphodiesterase activity, metal ion binding, protein binding, protein kinase B binding Human PDE4A Reactome UniProtKB {GO:0005515=PMID:11306681, GO:0007608=GO_REF:0000019, GO:0048471=PMID:11306681, GO:0004115=PMID:9677330, GO:0004114=GO_REF:0000002, GO:0010738=GO_REF:0000019, GO:0032587=GO_REF:0000039, GO:0035690=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_19387, GO:0007165=GO_REF:0000002, GO:0016020=PMID:9677330, GO:0043949=GO_REF:0000019, GO:0006198=PMID:17704206} P27815 cAMP-specific 3',5'-cyclic phosphodiesterase 4A protein 20130213 {GO:0005515=IPI, GO:0007608=IEA, GO:0048471=IDA, GO:0004115=TAS, GO:0004114=IEA, GO:0010738=IEA, GO:0032587=IEA, GO:0035690=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0007165=IEA, GO:0016020=TAS, GO:0043949=IEA, GO:0006198=IMP} cAMP catabolic process, cellular response to drug, regulation of cAMP-mediated signaling, regulation of protein kinase A signaling cascade, sensory perception of smell, signal transduction cytosol, membrane, perinuclear region of cytoplasm, ruffle membrane 3',5'-cyclic-AMP phosphodiesterase activity, 3',5'-cyclic-nucleotide phosphodiesterase activity, metal ion binding, protein binding Human PDE4B Reactome UniProtKB {GO:0007165=GO_REF:0000002, GO:0001780=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0071222=GO_REF:0000019, GO:0004115=GO_REF:0000019, GO:0030593=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0035690=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0006198=GO_REF:0000041, GO:0071944=GO_REF:0000019, GO:0005829=Reactome:REACT_19387} Q07343 cAMP-specific 3',5'-cyclic phosphodiesterase 4B protein 20130213 {GO:0007165=IEA, GO:0001780=IEA, GO:0048471=IEA, GO:0071222=IEA, GO:0004115=IEA, GO:0030593=IEA, GO:0005634=IEA, GO:0035690=IEA, GO:0046872=IEA, GO:0006198=IEA, GO:0071944=IEA, GO:0005829=TAS} cAMP catabolic process, cellular response to drug, cellular response to lipopolysaccharide, neutrophil chemotaxis, neutrophil homeostasis, signal transduction cell periphery, cytosol, nucleus, perinuclear region of cytoplasm 3',5'-cyclic-AMP phosphodiesterase activity, metal ion binding Human PDE4C ENSEMBL UniProtKB {GO:0007165=GO_REF:0000002, GO:0004115=PMID:9349724, GO:0004114=GO_REF:0000002, GO:0072372=GO_REF:0000019, GO:0046872=GO_REF:0000038, GO:0005829=Reactome:REACT_19387, GO:0006198=GO_REF:0000041} Q32MM7 PDE4C protein protein 20130413 {GO:0007165=IEA, GO:0004115=TAS, GO:0004114=IEA, GO:0072372=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0006198=IEA} cAMP catabolic process, signal transduction cytosol, primary cilium 3',5'-cyclic-AMP phosphodiesterase activity, 3',5'-cyclic-nucleotide phosphodiesterase activity, metal ion binding Human Ensembl:ENSMUSP00000034307 PDE4D Reactome UniProtKB {GO:0004115=PMID:9371713, GO:0005815=GO_REF:0000039, GO:0004114=PMID:10913353, GO:0007568=GO_REF:0000019, GO:0030593=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_19387, GO:0006939=GO_REF:0000019, GO:0007165=GO_REF:0000002, GO:0071222=GO_REF:0000019, GO:0030552=PMID:15938621, GO:0035264=GO_REF:0000019, GO:0016020=GO_REF:0000039, GO:0061028=GO_REF:0000024, GO:0008144=PMID:15938621, GO:0006198=PMID:19252089} Q08499 cAMP-specific 3',5'-cyclic phosphodiesterase 4D protein 20130213 {GO:0004115=TAS, GO:0005815=IEA, GO:0004114=NAS, GO:0007568=IEA, GO:0030593=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0006939=IEA, GO:0007165=IEA, GO:0071222=IEA, GO:0030552=IDA, GO:0035264=IEA, GO:0016020=IEA, GO:0061028=ISS, GO:0008144=IPI, GO:0006198=IMP} aging, cAMP catabolic process, cellular response to lipopolysaccharide, establishment of endothelial barrier, multicellular organism growth, neutrophil chemotaxis, signal transduction, smooth muscle contraction cytosol, membrane, microtubule organizing center 3',5'-cyclic-AMP phosphodiesterase activity, 3',5'-cyclic-nucleotide phosphodiesterase activity, cAMP binding, drug binding, metal ion binding Human PDE4DIP UniProtKB UniProtKB {GO:0005515=PMID:17923693, GO:0005737=PMID:11374908, GO:0005813=PMID:21399614, GO:0005794=PMID:11134006, GO:0005634=PMID:11374908, GO:0019899=PMID:11134006, GO:0030016=PMID:11134006, GO:0043623=PMID:11134006} Q5VU43 Myomegalin protein 20110517 {GO:0005515=IPI, GO:0005737=IDA, GO:0005813=IDA, GO:0005794=ISS, GO:0005634=IDA, GO:0019899=ISS, GO:0030016=ISS, GO:0043623=ISS} cellular protein complex assembly Golgi apparatus, centrosome, cytoplasm, myofibril, nucleus enzyme binding, protein binding Human PDE5A Reactome UniProtKB {GO:0009187=GO_REF:0000029, GO:0004114=PMID:9714779, GO:0047555=GO_REF:0000003, GO:0046069=PMID:14687666, GO:0005575=GO_REF:0000015, GO:0046068=GO_REF:0000019, GO:0046872=GO_REF:0000038, GO:0005829=Reactome:REACT_23959, GO:0042130=GO_REF:0000019, GO:0007165=GO_REF:0000029, GO:0030553=PMID:15938621, GO:0043406=GO_REF:0000019, GO:0060282=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0008270=GO_REF:0000029, GO:0055119=GO_REF:0000019, GO:0055118=GO_REF:0000019, GO:0010613=GO_REF:0000019} O76074 cGMP-specific 3',5'-cyclic phosphodiesterase protein 20130301 {GO:0009187=NAS, GO:0004114=NAS, GO:0047555=IEA, GO:0046069=IDA, GO:0005575=ND, GO:0046068=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0042130=IEA, GO:0007165=NAS, GO:0030553=TAS, GO:0043406=IEA, GO:0060282=IEA, GO:0007596=TAS, GO:0008270=NAS, GO:0055119=IEA, GO:0055118=IEA, GO:0010613=IEA} blood coagulation, cGMP catabolic process, cGMP metabolic process, cyclic nucleotide metabolic process, negative regulation of T cell proliferation, negative regulation of cardiac muscle contraction, positive regulation of MAP kinase activity, positive regulation of cardiac muscle hypertrophy, positive regulation of oocyte development, relaxation of cardiac muscle, signal transduction cellular_component, cytosol 3',5'-cyclic-GMP phosphodiesterase activity, 3',5'-cyclic-nucleotide phosphodiesterase activity, cGMP binding, metal ion binding, zinc ion binding Human PDE6A BHF-UCL UniProtKB {GO:0097381=Reactome:REACT_23959, GO:0007165=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0060041=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0051480=PMID:19946729, GO:0047555=PMID:19946729, GO:0046037=PMID:19946729, GO:0007601=GO_REF:0000037, GO:0046872=GO_REF:0000037} P16499 Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha protein 20100810 {GO:0097381=TAS, GO:0007165=IEA, GO:0005886=IEA, GO:0060041=IEA, GO:0007596=TAS, GO:0051480=IMP, GO:0047555=IMP, GO:0046037=IMP, GO:0007601=IEA, GO:0046872=IEA} GMP metabolic process, blood coagulation, cytosolic calcium ion homeostasis, retina development in camera-type eye, signal transduction, visual perception photoreceptor disc membrane, plasma membrane 3',5'-cyclic-GMP phosphodiesterase activity, metal ion binding Human PDE6B BHF-UCL UniProtKB {GO:0097381=Reactome:REACT_23959, GO:0007165=GO_REF:0000002, GO:0009583=GO_REF:0000019, GO:0007603=PMID:8394174, GO:0060041=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0004114=GO_REF:0000002, GO:0051480=PMID:19946729, GO:0047555=PMID:19946729, GO:0046037=PMID:19946729, GO:0007601=GO_REF:0000037, GO:0046872=GO_REF:0000037} P35913 Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta protein 20100810 {GO:0097381=TAS, GO:0007165=IEA, GO:0009583=IEA, GO:0007603=TAS, GO:0060041=IEA, GO:0007596=TAS, GO:0004114=IEA, GO:0051480=IMP, GO:0047555=IMP, GO:0046037=IMP, GO:0007601=IEA, GO:0046872=IEA} GMP metabolic process, blood coagulation, cytosolic calcium ion homeostasis, detection of light stimulus, phototransduction, visible light, retina development in camera-type eye, signal transduction, visual perception photoreceptor disc membrane 3',5'-cyclic-GMP phosphodiesterase activity, 3',5'-cyclic-nucleotide phosphodiesterase activity, metal ion binding Human PDE6C UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0046549=GO_REF:0000019, GO:0007603=GO_REF:0000019, GO:0030553=GO_REF:0000037, GO:0047555=GO_REF:0000003, GO:0007601=GO_REF:0000037, GO:0046872=GO_REF:0000037} P51160 Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' protein 20130413 {GO:0005886=IEA, GO:0046549=IEA, GO:0007603=IEA, GO:0030553=IEA, GO:0047555=IEA, GO:0007601=IEA, GO:0046872=IEA} phototransduction, visible light, retinal cone cell development, visual perception plasma membrane 3',5'-cyclic-GMP phosphodiesterase activity, cGMP binding, metal ion binding Human UniProtKB-SubCell:SL-0039 PDE6D IntAct UniProtKB {GO:0005515=PMID:11980706, GO:0004114=GO_REF:0000002, GO:0033124=GO_REF:0000024, GO:0005095=GO_REF:0000024, GO:0007601=GO_REF:0000037, GO:0050896=GO_REF:0000037} O43924 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta protein 20130415 {GO:0005515=IPI, GO:0004114=IEA, GO:0033124=ISS, GO:0005095=ISS, GO:0007601=IEA, GO:0050896=IEA} regulation of GTP catabolic process, response to stimulus, visual perception 3',5'-cyclic-nucleotide phosphodiesterase activity, GTPase inhibitor activity, protein binding Human UniProtKB:Q9D0J4 PDE6G GOC UniProtKB {GO:0004857=PMID:7828894, GO:0097381=Reactome:REACT_23959, GO:0000187=GO_REF:0000019, GO:0045745=GO_REF:0000019, GO:0030553=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0045742=GO_REF:0000019, GO:0047555=GO_REF:0000003, GO:0043086=PMID:7828894, GO:0007601=GO_REF:0000037} P18545 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma protein 20130413 {GO:0004857=TAS, GO:0097381=TAS, GO:0000187=IEA, GO:0045745=IEA, GO:0030553=IEA, GO:0007596=TAS, GO:0045742=IEA, GO:0047555=IEA, GO:0043086=TAS, GO:0007601=IEA} activation of MAPK activity, blood coagulation, negative regulation of catalytic activity, positive regulation of G-protein coupled receptor protein signaling pathway, positive regulation of epidermal growth factor receptor signaling pathway, visual perception photoreceptor disc membrane 3',5'-cyclic-GMP phosphodiesterase activity, cGMP binding, enzyme inhibitor activity Human PDE6H GOC UniProtKB {GO:0004857=PMID:8786098, GO:0000187=GO_REF:0000019, GO:0045745=GO_REF:0000019, GO:0030553=GO_REF:0000002, GO:0045742=GO_REF:0000019, GO:0047555=GO_REF:0000003, GO:0043086=PMID:8786098, GO:0007601=GO_REF:0000037, GO:0050896=GO_REF:0000037} Q13956 Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma protein 20130413 {GO:0004857=TAS, GO:0000187=IEA, GO:0045745=IEA, GO:0030553=IEA, GO:0045742=IEA, GO:0047555=IEA, GO:0043086=TAS, GO:0007601=IEA, GO:0050896=IEA} activation of MAPK activity, negative regulation of catalytic activity, positive regulation of G-protein coupled receptor protein signaling pathway, positive regulation of epidermal growth factor receptor signaling pathway, response to stimulus, visual perception 3',5'-cyclic-GMP phosphodiesterase activity, cGMP binding, enzyme inhibitor activity Human PDE7B Reactome UniProtKB {GO:0007165=GO_REF:0000002, GO:0004115=GO_REF:0000019, GO:0004114=GO_REF:0000002, GO:0007268=PMID:10814504, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_19387, GO:0006198=GO_REF:0000041} Q9NP56 cAMP-specific 3',5'-cyclic phosphodiesterase 7B protein 20090423 {GO:0007165=IEA, GO:0004115=IEA, GO:0004114=IEA, GO:0007268=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0006198=IEA} cAMP catabolic process, signal transduction, synaptic transmission cytosol 3',5'-cyclic-AMP phosphodiesterase activity, 3',5'-cyclic-nucleotide phosphodiesterase activity, metal ion binding Human PDE8A Reactome UniProtKB {GO:0006355=GO_REF:0000002, GO:0009187=PMID:9618252, GO:0004115=GO_REF:0000019, GO:0004114=PMID:9618252, GO:0000156=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_19387, GO:0006198=GO_REF:0000041} O60658 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A protein 20090423 {GO:0006355=IEA, GO:0009187=NAS, GO:0004115=IEA, GO:0004114=NAS, GO:0000156=IEA, GO:0005575=ND, GO:0046872=IEA, GO:0005829=TAS, GO:0006198=IEA} cAMP catabolic process, cyclic nucleotide metabolic process, regulation of transcription, DNA-dependent cellular_component, cytosol 3',5'-cyclic-AMP phosphodiesterase activity, 3',5'-cyclic-nucleotide phosphodiesterase activity, metal ion binding, phosphorelay response regulator activity Human PDE8B Reactome UniProtKB {GO:0006355=GO_REF:0000002, GO:0009187=PMID:9784418, GO:0004114=PMID:9784418, GO:0000156=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0004871=GO_REF:0000002, GO:0046676=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_19387, GO:0006198=GO_REF:0000041} O95263 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B protein 20090423 {GO:0006355=IEA, GO:0009187=NAS, GO:0004114=NAS, GO:0000156=IEA, GO:0005575=ND, GO:0004871=IEA, GO:0046676=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0006198=IEA} cAMP catabolic process, cyclic nucleotide metabolic process, negative regulation of insulin secretion, regulation of transcription, DNA-dependent cellular_component, cytosol 3',5'-cyclic-nucleotide phosphodiesterase activity, metal ion binding, phosphorelay response regulator activity, signal transducer activity Human PDE9A IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0007165=GO_REF:0000002, GO:0048471=GO_REF:0000039, GO:0005794=GO_REF:0000039, GO:0007596=Reactome:REACT_604, GO:0005783=GO_REF:0000039, GO:0004114=PMID:9856478, GO:0047555=GO_REF:0000003, GO:0032587=GO_REF:0000039, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_23959} O76083 High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A protein 20130415 {GO:0005515=IPI, GO:0007165=IEA, GO:0048471=IEA, GO:0005794=IEA, GO:0007596=TAS, GO:0005783=IEA, GO:0004114=TAS, GO:0047555=IEA, GO:0032587=IEA, GO:0046872=IEA, GO:0005829=TAS} blood coagulation, signal transduction Golgi apparatus, cytosol, endoplasmic reticulum, perinuclear region of cytoplasm, ruffle membrane 3',5'-cyclic-GMP phosphodiesterase activity, 3',5'-cyclic-nucleotide phosphodiesterase activity, metal ion binding, protein binding Human UniProtKB:Q13049 PDGFA BHF-UCL UniProtKB {GO:0043498=PMID:291037, GO:0043499=PMID:12070119, GO:0050730=GO_REF:0000024, GO:0005518=PMID:8900172, GO:0009790=PMID:10508235, GO:0005615=PMID:3754619, GO:0042803=PMID:3754619, GO:0010035=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0032956=PMID:10508235, GO:0009887=GO_REF:0000024, GO:0051781=GO_REF:0000037, GO:0007179=GO_REF:0000019, GO:0070374=PMID:11788434, GO:0032355=GO_REF:0000019, GO:0001942=GO_REF:0000024, GO:0035793=PMID:19019919, GO:0048839=GO_REF:0000019, GO:0030335=PMID:17470632, GO:0060683=GO_REF:0000024, GO:0046982=PMID:7073684, GO:0048286=GO_REF:0000024, GO:0009986=PMID:291037, GO:0048407=PMID:7073684, GO:0010512=PMID:2538439, GO:0045740=PMID:2439522, GO:0030168=Reactome:REACT_798, GO:0014068=PMID:11788434, GO:0005161=PMID:2439522, GO:0008543=Reactome:REACT_9470, GO:0030031=GO_REF:0000024, GO:0045087=Reactome:REACT_6802, GO:0042060=PMID:10508235, GO:0005788=Reactome:REACT_17051, GO:0043588=GO_REF:0000024, GO:0008083=GO_REF:0000037, GO:2000278=PMID:11788434, GO:0010544=PMID:2538439, GO:0051897=PMID:19019919, GO:0008284=PMID:17470632, GO:0030036=GO_REF:0000024, GO:0014910=PMID:9409235, GO:0007267=PMID:2842868, GO:0048146=PMID:2439522, GO:0043406=PMID:11788434, GO:0031093=Reactome:REACT_21351, GO:0032526=GO_REF:0000019, GO:0001775=PMID:10508235, GO:0031954=PMID:12070119, GO:0072124=PMID:11788434, GO:0001666=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0042493=GO_REF:0000019, GO:0048015=Reactome:REACT_12464, GO:0050919=PMID:9409235, GO:0009611=PMID:2538439, GO:0002053=GO_REF:0000024, GO:0005576=Reactome:REACT_147854, GO:0001525=GO_REF:0000024, GO:0005902=GO_REF:0000024, GO:0016020=GO_REF:0000002, GO:0000139=Reactome:REACT_17059, GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0048008=PMID:2439522, GO:0043410=PMID:11788434} P04085 Platelet-derived growth factor subunit A protein 20080502 {GO:0043498=IDA, GO:0043499=IDA, GO:0050730=ISS, GO:0005518=IDA, GO:0009790=TAS, GO:0005615=IDA, GO:0042803=IDA, GO:0010035=IEA, GO:0007173=TAS, GO:0032956=TAS, GO:0009887=ISS, GO:0051781=IEA, GO:0007179=IEA, GO:0070374=IDA, GO:0032355=IEA, GO:0001942=ISS, GO:0035793=IDA, GO:0048839=IEA, GO:0030335=IDA, GO:0060683=ISS, GO:0046982=IPI, GO:0048286=ISS, GO:0009986=IDA, GO:0048407=IPI, GO:0010512=IDA, GO:0045740=IDA, GO:0030168=TAS, GO:0014068=IDA, GO:0005161=IDA, GO:0008543=TAS, GO:0030031=ISS, GO:0045087=TAS, GO:0042060=TAS, GO:0005788=TAS, GO:0043588=ISS, GO:0008083=IEA, GO:2000278=IDA, GO:0010544=IDA, GO:0051897=IDA, GO:0008284=IDA, GO:0030036=ISS, GO:0014910=IDA, GO:0007267=TAS, GO:0048146=IDA, GO:0043406=IDA, GO:0031093=TAS, GO:0032526=IEA, GO:0001775=TAS, GO:0031954=IDA, GO:0072124=IDA, GO:0001666=IEA, GO:0048011=TAS, GO:0042493=IEA, GO:0048015=TAS, GO:0050919=IDA, GO:0009611=IDA, GO:0002053=ISS, GO:0005576=TAS, GO:0001525=ISS, GO:0005902=ISS, GO:0016020=IEA, GO:0000139=TAS, GO:0007596=TAS, GO:0002576=TAS, GO:0048008=IDA, GO:0043410=IMP} actin cytoskeleton organization, angiogenesis, blood coagulation, cell activation, cell projection assembly, cell-cell signaling, embryo development, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, hair follicle development, innate immune response, inner ear development, lung alveolus development, negative chemotaxis, negative regulation of phosphatidylinositol biosynthetic process, negative regulation of platelet activation, neurotrophin TRK receptor signaling pathway, organ morphogenesis, phosphatidylinositol-mediated signaling, platelet activation, platelet degranulation, platelet-derived growth factor receptor signaling pathway, positive regulation of DNA replication, positive regulation of ERK1 and ERK2 cascade, positive regulation of MAP kinase activity, positive regulation of MAPK cascade, positive regulation of cell division, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of fibroblast proliferation, positive regulation of mesenchymal cell proliferation, positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of protein autophosphorylation, positive regulation of protein kinase B signaling cascade, regulation of DNA biosynthetic process, regulation of actin cytoskeleton organization, regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling, regulation of glomerular mesangial cell proliferation, regulation of peptidyl-tyrosine phosphorylation, regulation of smooth muscle cell migration, response to drug, response to estradiol stimulus, response to hypoxia, response to inorganic substance, response to retinoic acid, response to wounding, skin development, transforming growth factor beta receptor signaling pathway, wound healing Golgi membrane, cell surface, endoplasmic reticulum lumen, extracellular region, extracellular space, membrane, microvillus, platelet alpha granule lumen cell surface binding, collagen binding, eukaryotic cell surface binding, growth factor activity, platelet-derived growth factor binding, platelet-derived growth factor receptor binding, protein heterodimerization activity, protein homodimerization activity Human PDGFB GOC UniProtKB {GO:0005515=PMID:2536956, GO:0043498=PMID:291037, GO:0043499=PMID:12070119, GO:0050730=GO_REF:0000019, GO:0005518=PMID:8900172, GO:0050731=PMID:21245381, GO:0005615=GO_REF:0000033, GO:0042803=PMID:2836953, GO:0007507=GO_REF:0000024, GO:0007173=Reactome:REACT_9417, GO:0018105=PMID:16530387, GO:0043552=PMID:16530387, GO:0007179=GO_REF:0000024, GO:0051781=GO_REF:0000037, GO:0070374=PMID:11788434, GO:0032355=GO_REF:0000019, GO:0035793=PMID:19019919, GO:0032868=GO_REF:0000019, GO:0030336=GO_REF:0000019, GO:0030335=PMID:21245381, GO:0046982=PMID:7073684, GO:0009986=PMID:291037, GO:0045743=GO_REF:0000019, GO:0048407=PMID:7073684, GO:0010512=PMID:2538439, GO:0045740=PMID:2439522, GO:0030168=Reactome:REACT_798, GO:0001892=GO_REF:0000024, GO:0014068=PMID:10734101, GO:0045840=PMID:10734101, GO:0018108=PMID:10734101, GO:0005161=PMID:2439522, GO:0042056=PMID:21245381, GO:0043536=PMID:9685360, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0030031=GO_REF:0000019, GO:0042060=GO_REF:0000019, GO:0005788=Reactome:REACT_17051, GO:0016049=GO_REF:0000019, GO:0045893=PMID:16530387, GO:2000379=PMID:19019919, GO:0008083=GO_REF:0000037, GO:0045892=PMID:16530387, GO:0060445=GO_REF:0000019, GO:0010544=PMID:2538439, GO:0008284=PMID:7073684, GO:0030036=GO_REF:0000019, GO:2000573=PMID:11788434, GO:0061098=PMID:16530387, GO:0006929=GO_REF:0000019, GO:0048514=GO_REF:0000019, GO:0045737=PMID:16530387, GO:0048146=PMID:2439522, GO:0090280=PMID:19019919, GO:0014911=PMID:9409235, GO:0032147=PMID:16530387, GO:0016323=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0016176=PMID:17942966, GO:0050921=PMID:9409235, GO:0043406=PMID:9685360, GO:0060664=GO_REF:0000019, GO:0072255=GO_REF:0000024, GO:0032148=PMID:16530387, GO:0031093=Reactome:REACT_21351, GO:0031954=PMID:12070119, GO:0030097=PMID:11264163, GO:0001666=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0048015=Reactome:REACT_12464, GO:0042493=GO_REF:0000019, GO:0072593=PMID:17942966, GO:0009611=PMID:2538439, GO:0005576=Reactome:REACT_147854, GO:0003104=GO_REF:0000024, GO:0038001=GO_REF:0000024, GO:0048661=PMID:12070119, GO:0072126=PMID:11788434, GO:0050918=PMID:21245381, GO:0002548=PMID:17991872, GO:0006260=GO_REF:0000019, GO:0072262=GO_REF:0000019, GO:0072264=GO_REF:0000019, GO:0071363=PMID:21245381, GO:0000139=Reactome:REACT_17059, GO:0001938=PMID:9685360, GO:0007596=Reactome:REACT_604, GO:0060326=PMID:21245381, GO:0002576=Reactome:REACT_318, GO:0071506=GO_REF:0000024, GO:2000591=PMID:10734101, GO:0006468=PMID:17942966, GO:0048008=PMID:2439522, GO:0043410=PMID:11788434} P01127 Platelet-derived growth factor subunit B protein 20130413 {GO:0005515=IPI, GO:0043498=IDA, GO:0043499=IDA, GO:0050730=IEA, GO:0005518=IDA, GO:0050731=IDA, GO:0005615=IBA, GO:0042803=IDA, GO:0007507=ISS, GO:0007173=TAS, GO:0018105=IDA, GO:0043552=IDA, GO:0007179=ISS, GO:0051781=IEA, GO:0070374=IDA, GO:0032355=IEA, GO:0035793=IDA, GO:0032868=IEA, GO:0030336=IEA, GO:0030335=IDA, GO:0046982=IPI, GO:0009986=IDA, GO:0045743=IEA, GO:0048407=IPI, GO:0010512=IDA, GO:0045740=IDA, GO:0030168=TAS, GO:0001892=ISS, GO:0014068=IDA, GO:0045840=IDA, GO:0018108=IDA, GO:0005161=IDA, GO:0042056=IDA, GO:0043536=IDA, GO:0008543=TAS, GO:0045087=TAS, GO:0030031=IEA, GO:0042060=IEA, GO:0005788=TAS, GO:0016049=IEA, GO:0045893=IDA, GO:2000379=IDA, GO:0008083=IEA, GO:0045892=IDA, GO:0060445=IEA, GO:0010544=IDA, GO:0008284=IDA, GO:0030036=IEA, GO:2000573=IDA, GO:0061098=IDA, GO:0006929=IEA, GO:0048514=IEA, GO:0045737=IDA, GO:0048146=IDA, GO:0090280=IDA, GO:0014911=IDA, GO:0032147=IDA, GO:0016323=ISS, GO:0005737=ISS, GO:0016176=IDA, GO:0050921=IDA, GO:0043406=IDA, GO:0060664=IEA, GO:0072255=ISS, GO:0032148=IDA, GO:0031093=TAS, GO:0031954=IDA, GO:0030097=IMP, GO:0001666=IEA, GO:0048011=TAS, GO:0048015=TAS, GO:0042493=IEA, GO:0072593=IMP, GO:0009611=IDA, GO:0005576=TAS, GO:0003104=ISS, GO:0038001=ISS, GO:0048661=IDA, GO:0072126=IDA, GO:0050918=IDA, GO:0002548=IDA, GO:0006260=IEA, GO:0072262=IEA, GO:0072264=IEA, GO:0071363=IDA, GO:0000139=TAS, GO:0001938=IDA, GO:0007596=TAS, GO:0060326=IDA, GO:0002576=TAS, GO:0071506=ISS, GO:2000591=IDA, GO:0006468=IDA, GO:0048008=IDA, GO:0043410=IMP} DNA replication, actin cytoskeleton organization, activation of protein kinase B activity, activation of protein kinase activity, blood coagulation, blood vessel morphogenesis, branching involved in salivary gland morphogenesis, cell chemotaxis, cell growth, cell projection assembly, cellular response to growth factor stimulus, cellular response to mycophenolic acid, embryonic placenta development, epidermal growth factor receptor signaling pathway, epithelial cell proliferation involved in salivary gland morphogenesis, fibroblast growth factor receptor signaling pathway, heart development, hemopoiesis, innate immune response, metanephric glomerular endothelium development, metanephric glomerular mesangial cell development, metanephric glomerular mesangial cell proliferation involved in metanephros development, monocyte chemotaxis, negative regulation of cell migration, negative regulation of phosphatidylinositol biosynthetic process, negative regulation of platelet activation, negative regulation of transcription, DNA-dependent, neurotrophin TRK receptor signaling pathway, paracrine signaling, peptidyl-serine phosphorylation, peptidyl-tyrosine phosphorylation, phosphatidylinositol-mediated signaling, platelet activation, platelet degranulation, platelet-derived growth factor receptor signaling pathway, positive chemotaxis, positive regulation of DNA biosynthetic process, positive regulation of DNA replication, positive regulation of ERK1 and ERK2 cascade, positive regulation of MAP kinase activity, positive regulation of MAPK cascade, positive regulation of blood vessel endothelial cell migration, positive regulation of calcium ion import, positive regulation of cell division, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of chemotaxis, positive regulation of cyclin-dependent protein kinase activity, positive regulation of endothelial cell proliferation, positive regulation of fibroblast growth factor receptor signaling pathway, positive regulation of fibroblast proliferation, positive regulation of glomerular filtration, positive regulation of glomerular mesangial cell proliferation, positive regulation of metanephric mesenchymal cell migration, positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway, positive regulation of mitosis, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of phosphatidylinositol 3-kinase activity, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of protein autophosphorylation, positive regulation of protein tyrosine kinase activity, positive regulation of reactive oxygen species metabolic process, positive regulation of smooth muscle cell migration, positive regulation of smooth muscle cell proliferation, positive regulation of transcription, DNA-dependent, protein phosphorylation, reactive oxygen species metabolic process, regulation of peptidyl-tyrosine phosphorylation, response to drug, response to estradiol stimulus, response to hypoxia, response to insulin stimulus, response to wounding, substrate-dependent cell migration, transforming growth factor beta receptor signaling pathway, wound healing Golgi membrane, basolateral plasma membrane, cell surface, cytoplasm, endoplasmic reticulum lumen, extracellular region, extracellular space, platelet alpha granule lumen cell surface binding, chemoattractant activity, collagen binding, eukaryotic cell surface binding, growth factor activity, platelet-derived growth factor binding, platelet-derived growth factor receptor binding, protein binding, protein heterodimerization activity, protein homodimerization activity, superoxide-generating NADPH oxidase activator activity Human PDGFC BHF-UCL UniProtKB {GO:0048010=Reactome:REACT_12529, GO:0043498=PMID:10806482, GO:0008284=GO_REF:0000019, GO:0050730=GO_REF:0000019, GO:0045740=PMID:10806482, GO:0005576=Reactome:REACT_17022, GO:0005634=GO_REF:0000039, GO:0048146=PMID:10806482, GO:0005161=PMID:10806482, GO:0007417=PMID:10858496, GO:0005615=PMID:10806482, GO:0042803=PMID:10806482, GO:0007171=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0071230=GO_REF:0000019, GO:0000139=Reactome:REACT_17051, GO:0005788=Reactome:REACT_17051, GO:0009887=GO_REF:0000019, GO:0051781=GO_REF:0000037, GO:0048008=PMID:10806482, GO:0008083=GO_REF:0000037} Q9NRA1 Platelet-derived growth factor C protein 20090720 {GO:0048010=TAS, GO:0043498=IDA, GO:0008284=IEA, GO:0050730=IEA, GO:0045740=IDA, GO:0005576=TAS, GO:0005634=IEA, GO:0048146=IDA, GO:0005161=IPI, GO:0007417=TAS, GO:0005615=IDA, GO:0042803=IPI, GO:0007171=IEA, GO:0016020=IEA, GO:0071230=IEA, GO:0000139=TAS, GO:0005788=TAS, GO:0009887=IEA, GO:0051781=IEA, GO:0048008=IDA, GO:0008083=IEA} activation of transmembrane receptor protein tyrosine kinase activity, cellular response to amino acid stimulus, central nervous system development, organ morphogenesis, platelet-derived growth factor receptor signaling pathway, positive regulation of DNA replication, positive regulation of cell division, positive regulation of cell proliferation, positive regulation of fibroblast proliferation, regulation of peptidyl-tyrosine phosphorylation, vascular endothelial growth factor receptor signaling pathway Golgi membrane, endoplasmic reticulum lumen, extracellular region, extracellular space, membrane, nucleus cell surface binding, growth factor activity, platelet-derived growth factor receptor binding, protein homodimerization activity Human PDGFD Reactome UniProtKB {GO:0000139=Reactome:REACT_17051, GO:0071230=GO_REF:0000019, GO:0050730=GO_REF:0000019, GO:0005788=Reactome:REACT_17051, GO:0005576=Reactome:REACT_17022, GO:0051781=GO_REF:0000037, GO:0007275=GO_REF:0000037, GO:0005161=GO_REF:0000002, GO:0008083=GO_REF:0000037} Q9GZP0 Platelet-derived growth factor D protein 20081121 {GO:0000139=TAS, GO:0071230=IEA, GO:0050730=IEA, GO:0005788=TAS, GO:0005576=TAS, GO:0051781=IEA, GO:0007275=IEA, GO:0005161=IEA, GO:0008083=IEA} cellular response to amino acid stimulus, multicellular organismal development, positive regulation of cell division, regulation of peptidyl-tyrosine phosphorylation Golgi membrane, endoplasmic reticulum lumen, extracellular region growth factor activity, platelet-derived growth factor receptor binding Human PDGFRA BHF-UCL UniProtKB {GO:0005515=PMID:17470632, GO:0001553=GO_REF:0000024, GO:0031226=PMID:2554309, GO:0048704=GO_REF:0000024, GO:0048701=GO_REF:0000024, GO:0042803=PMID:2542288, GO:0030539=GO_REF:0000019, GO:2000249=PMID:10734113, GO:0072277=GO_REF:0000024, GO:0046777=PMID:2536956, GO:0007173=Reactome:REACT_9417, GO:0043552=PMID:1646396, GO:0030198=GO_REF:0000019, GO:0035790=PMID:2554309, GO:0055003=GO_REF:0000024, GO:0070374=PMID:10734113, GO:0038085=PMID:17470632, GO:0030335=PMID:17470632, GO:0048407=PMID:2536956, GO:0023019=GO_REF:0000019, GO:0045740=PMID:10806482, GO:0018108=PMID:2536956, GO:0014068=PMID:10734113, GO:0005161=PMID:2542288, GO:0001701=GO_REF:0000019, GO:0005887=PMID:2536956, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0042060=GO_REF:0000024, GO:0009897=GO_REF:0000019, GO:0010544=PMID:8188664, GO:0008284=PMID:2554309, GO:0005018=PMID:2536956, GO:0030325=GO_REF:0000019, GO:0005886=Reactome:REACT_147854, GO:0030324=GO_REF:0000019, GO:0061298=GO_REF:0000024, GO:2000739=PMID:21596750, GO:0005634=GO_REF:0000024, GO:0048146=PMID:10806482, GO:0007204=PMID:2554309, GO:0005737=GO_REF:0000024, GO:0071230=GO_REF:0000019, GO:0050920=PMID:2554309, GO:0042475=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:0005021=PMID:17470632, GO:0001775=PMID:10508235, GO:0048010=GO_REF:0000002, GO:0048011=Reactome:REACT_11061, GO:0048015=Reactome:REACT_12464, GO:0005524=GO_REF:0000037, GO:0010863=PMID:1646396, GO:0070527=PMID:8188664, GO:0008210=GO_REF:0000019, GO:0048557=GO_REF:0000024, GO:0060325=GO_REF:0000019, GO:0060326=PMID:1646396, GO:0019048=GO_REF:0000037, GO:0033327=GO_REF:0000019, GO:0048008=PMID:2536956, GO:0004714=PMID:1646396} P16234 Platelet-derived growth factor receptor alpha protein 20080429 {GO:0005515=IPI, GO:0001553=ISS, GO:0031226=IDA, GO:0048704=ISS, GO:0048701=ISS, GO:0042803=IDA, GO:0030539=IEA, GO:2000249=TAS, GO:0072277=ISS, GO:0046777=IDA, GO:0007173=TAS, GO:0043552=IMP, GO:0030198=IEA, GO:0035790=IMP, GO:0055003=ISS, GO:0070374=IMP, GO:0038085=IPI, GO:0030335=IDA, GO:0048407=IPI, GO:0023019=IEA, GO:0045740=IDA, GO:0018108=IDA, GO:0014068=TAS, GO:0005161=IPI, GO:0001701=IEA, GO:0005887=IDA, GO:0008543=TAS, GO:0045087=TAS, GO:0042060=ISS, GO:0009897=IEA, GO:0010544=IDA, GO:0008284=IMP, GO:0005018=IDA, GO:0030325=IEA, GO:0005886=TAS, GO:0030324=IEA, GO:0061298=ISS, GO:2000739=IMP, GO:0005634=ISS, GO:0048146=IDA, GO:0007204=IMP, GO:0005737=ISS, GO:0071230=IEA, GO:0050920=IMP, GO:0042475=IEA, GO:0060021=IEA, GO:0005021=IDA, GO:0001775=TAS, GO:0048010=IEA, GO:0048011=TAS, GO:0048015=TAS, GO:0005524=IEA, GO:0010863=IMP, GO:0070527=IMP, GO:0008210=IEA, GO:0048557=ISS, GO:0060325=IEA, GO:0060326=IMP, GO:0019048=IEA, GO:0033327=IEA, GO:0048008=IDA, GO:0004714=IDA} Leydig cell differentiation, adrenal gland development, cardiac myofibril assembly, cell activation, cell chemotaxis, cellular response to amino acid stimulus, elevation of cytosolic calcium ion concentration, embryonic cranial skeleton morphogenesis, embryonic digestive tract morphogenesis, embryonic skeletal system morphogenesis, epidermal growth factor receptor signaling pathway, estrogen metabolic process, extracellular matrix organization, face morphogenesis, fibroblast growth factor receptor signaling pathway, in utero embryonic development, innate immune response, lung development, luteinization, male genitalia development, metanephric glomerular capillary formation, negative regulation of platelet activation, neurotrophin TRK receptor signaling pathway, odontogenesis of dentin-containing tooth, palate development, peptidyl-tyrosine phosphorylation, phosphatidylinositol-mediated signaling, platelet aggregation, platelet-derived growth factor receptor signaling pathway, platelet-derived growth factor receptor-alpha signaling pathway, positive regulation of DNA replication, positive regulation of ERK1 and ERK2 cascade, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of fibroblast proliferation, positive regulation of phosphatidylinositol 3-kinase activity, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of phospholipase C activity, protein autophosphorylation, regulation of actin cytoskeleton reorganization, regulation of chemotaxis, regulation of mesenchymal stem cell differentiation, retina vasculature development in camera-type eye, signal transduction involved in regulation of gene expression, vascular endothelial growth factor receptor signaling pathway, virus-host interaction, wound healing cytoplasm, external side of plasma membrane, integral to plasma membrane, intrinsic to plasma membrane, nucleus, plasma membrane ATP binding, platelet-derived growth factor alpha-receptor activity, platelet-derived growth factor binding, platelet-derived growth factor receptor binding, protein binding, protein homodimerization activity, transmembrane receptor protein tyrosine kinase activity, vascular endothelial growth factor binding, vascular endothelial growth factor-activated receptor activity Human UniProtKB:P04085 PDGFRB GOC UniProtKB {GO:0005515=PMID:16477012, GO:0042542=GO_REF:0000019, GO:0050730=GO_REF:0000019, GO:0035789=GO_REF:0000019, GO:0034405=GO_REF:0000019, GO:0071670=GO_REF:0000024, GO:0031226=PMID:2554309, GO:0048705=GO_REF:0000019, GO:0007243=GO_REF:0000019, GO:0072075=GO_REF:0000019, GO:0072278=GO_REF:0000019, GO:0072277=GO_REF:0000024, GO:0004992=PMID:2536956, GO:0046777=PMID:2536956, GO:0007173=Reactome:REACT_9417, GO:0001894=GO_REF:0000019, GO:0072275=GO_REF:0000019, GO:0043552=PMID:1314164, GO:0016301=GO_REF:0000019, GO:0032956=GO_REF:0000024, GO:0035441=GO_REF:0000024, GO:0048745=GO_REF:0000019, GO:0035791=PMID:2554309, GO:0055003=GO_REF:0000024, GO:0007179=GO_REF:0000019, GO:0070374=PMID:21679854, GO:0032355=GO_REF:0000019, GO:0038085=PMID:17470632, GO:0035793=GO_REF:0000024, GO:0048839=GO_REF:0000019, GO:0030335=PMID:17470632, GO:0048407=PMID:2536956, GO:0046488=PMID:1653029, GO:0009636=GO_REF:0000019, GO:0014068=GO_REF:0000024, GO:0018108=PMID:2536956, GO:0045840=GO_REF:0000024, GO:0005161=PMID:2542288, GO:0001701=GO_REF:0000019, GO:0032967=GO_REF:0000019, GO:0072284=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0005887=GO_REF:0000002, GO:0045087=Reactome:REACT_6802, GO:0042060=GO_REF:0000019, GO:0055093=GO_REF:0000019, GO:2000379=GO_REF:0000024, GO:0043548=GO_REF:0000019, GO:0005019=PMID:2536956, GO:0008284=PMID:2554309, GO:0005886=Reactome:REACT_147854, GO:0030325=GO_REF:0000019, GO:2000573=GO_REF:0000024, GO:0061298=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0090280=GO_REF:0000024, GO:0014911=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0016324=GO_REF:0000024, GO:0036120=PMID:2536956, GO:0050921=GO_REF:0000024, GO:0043406=GO_REF:0000024, GO:0005021=GO_REF:0000002, GO:0032526=GO_REF:0000019, GO:0004871=GO_REF:0000019, GO:0043202=GO_REF:0000039, GO:0048010=GO_REF:0000002, GO:0048011=Reactome:REACT_11061, GO:0048015=Reactome:REACT_12464, GO:0035909=GO_REF:0000024, GO:0005102=PMID:10821867, GO:0005524=GO_REF:0000037, GO:0048661=PMID:21679854, GO:0006024=GO_REF:0000019, GO:0010863=PMID:1653029, GO:0072262=GO_REF:0000024, GO:0007165=PMID:10821867, GO:0016020=PMID:16477012, GO:0016477=PMID:2554309, GO:0060326=PMID:17991872, GO:0032516=PMID:7691811, GO:0060981=GO_REF:0000024, GO:0016023=GO_REF:0000039, GO:0004713=PMID:1653029, GO:0048008=PMID:2536956, GO:0005017=PMID:2536956} P09619 Platelet-derived growth factor receptor beta protein 20130413 {GO:0005515=IPI, GO:0042542=IEA, GO:0050730=IEA, GO:0035789=IEA, GO:0034405=IEA, GO:0071670=ISS, GO:0031226=IDA, GO:0048705=IEA, GO:0007243=IEA, GO:0072075=IEA, GO:0072278=IEA, GO:0072277=ISS, GO:0004992=TAS, GO:0046777=IDA, GO:0007173=TAS, GO:0001894=IEA, GO:0072275=IEA, GO:0043552=IDA, GO:0016301=IEA, GO:0032956=ISS, GO:0035441=ISS, GO:0048745=IEA, GO:0035791=IMP, GO:0055003=ISS, GO:0007179=IEA, GO:0070374=IMP, GO:0032355=IEA, GO:0038085=IPI, GO:0035793=ISS, GO:0048839=IEA, GO:0030335=IDA, GO:0048407=IPI, GO:0046488=IMP, GO:0009636=IEA, GO:0014068=ISS, GO:0018108=IDA, GO:0045840=ISS, GO:0005161=IPI, GO:0001701=IEA, GO:0032967=IEA, GO:0072284=IEA, GO:0008543=TAS, GO:0005887=IEA, GO:0045087=TAS, GO:0042060=IEA, GO:0055093=IEA, GO:2000379=ISS, GO:0043548=IEA, GO:0005019=IDA, GO:0008284=IMP, GO:0005886=TAS, GO:0030325=IEA, GO:2000573=ISS, GO:0061298=ISS, GO:0005634=ISS, GO:0090280=ISS, GO:0014911=ISS, GO:0005737=ISS, GO:0016324=ISS, GO:0036120=TAS, GO:0050921=ISS, GO:0043406=ISS, GO:0005021=IEA, GO:0032526=IEA, GO:0004871=IEA, GO:0043202=IEA, GO:0048010=IEA, GO:0048011=TAS, GO:0048015=TAS, GO:0035909=ISS, GO:0005102=IPI, GO:0005524=IEA, GO:0048661=IMP, GO:0006024=IEA, GO:0010863=IDA, GO:0072262=ISS, GO:0007165=IDA, GO:0016020=IDA, GO:0016477=IMP, GO:0060326=IDA, GO:0032516=IDA, GO:0060981=ISS, GO:0016023=IEA, GO:0004713=IDA, GO:0048008=IDA, GO:0005017=TAS} adrenal gland development, aorta morphogenesis, cardiac myofibril assembly, cell chemotaxis, cell migration, cell migration involved in coronary angiogenesis, cell migration involved in vasculogenesis, cellular response to platelet-derived growth factor stimulus, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, glycosaminoglycan biosynthetic process, in utero embryonic development, innate immune response, inner ear development, intracellular protein kinase cascade, metanephric S-shaped body morphogenesis, metanephric comma-shaped body morphogenesis, metanephric glomerular capillary formation, metanephric glomerular mesangial cell proliferation involved in metanephros development, metanephric glomerulus morphogenesis, metanephric mesenchymal cell migration, metanephric mesenchyme development, neurotrophin TRK receptor signaling pathway, peptidyl-tyrosine phosphorylation, phosphatidylinositol metabolic process, phosphatidylinositol-mediated signaling, platelet-derived growth factor receptor signaling pathway, platelet-derived growth factor receptor-beta signaling pathway, positive regulation of DNA biosynthetic process, positive regulation of ERK1 and ERK2 cascade, positive regulation of MAP kinase activity, positive regulation of calcium ion import, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of chemotaxis, positive regulation of collagen biosynthetic process, positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway, positive regulation of mitosis, positive regulation of phosphatidylinositol 3-kinase activity, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of phospholipase C activity, positive regulation of phosphoprotein phosphatase activity, positive regulation of reactive oxygen species metabolic process, positive regulation of smooth muscle cell migration, positive regulation of smooth muscle cell proliferation, protein autophosphorylation, regulation of actin cytoskeleton organization, regulation of peptidyl-tyrosine phosphorylation, response to estradiol stimulus, response to fluid shear stress, response to hydrogen peroxide, response to hyperoxia, response to retinoic acid, response to toxic substance, retina vasculature development in camera-type eye, signal transduction, skeletal system morphogenesis, smooth muscle cell chemotaxis, smooth muscle tissue development, tissue homeostasis, transforming growth factor beta receptor signaling pathway, vascular endothelial growth factor receptor signaling pathway, wound healing apical plasma membrane, cytoplasm, cytoplasmic membrane-bounded vesicle, integral to plasma membrane, intrinsic to plasma membrane, lysosomal lumen, membrane, nucleus, plasma membrane ATP binding, kinase activity, phosphatidylinositol 3-kinase binding, platelet activating factor receptor activity, platelet-derived growth factor beta-receptor activity, platelet-derived growth factor binding, platelet-derived growth factor receptor binding, platelet-derived growth factor-activated receptor activity, protein binding, protein tyrosine kinase activity, receptor binding, signal transducer activity, vascular endothelial growth factor binding, vascular endothelial growth factor-activated receptor activity Human PDHA1 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0010510=Reactome:REACT_12528, GO:0006099=PMID:19081061, GO:0006090=Reactome:REACT_2071, GO:0005759=Reactome:REACT_12543, GO:0016624=GO_REF:0000002, GO:0004738=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0004739=GO_REF:0000003, GO:0045254=PMID:19081061, GO:0006096=GO_REF:0000002, GO:0006086=PMID:19081061} Q5JPU3 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0010510=TAS, GO:0006099=IDA, GO:0006090=TAS, GO:0005759=TAS, GO:0016624=IEA, GO:0004738=IEA, GO:0044281=TAS, GO:0004739=IEA, GO:0045254=IDA, GO:0006096=IEA, GO:0006086=IDA} acetyl-CoA biosynthetic process from pyruvate, glycolysis, pyruvate metabolic process, regulation of acetyl-CoA biosynthetic process from pyruvate, small molecule metabolic process, tricarboxylic acid cycle mitochondrial matrix, mitochondrion, pyruvate dehydrogenase complex oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor, pyruvate dehydrogenase (acetyl-transferring) activity, pyruvate dehydrogenase activity Human Ensembl:ENSMUSP00000033662 PDHA2 UniProtKB UniProtKB {GO:0006099=GO_REF:0000037, GO:0006090=PMID:16436377, GO:0005759=GO_REF:0000039, GO:0004739=PMID:16436377, GO:0006096=GO_REF:0000002} P29803 Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial protein 20121204 {GO:0006099=IEA, GO:0006090=IDA, GO:0005759=IEA, GO:0004739=IDA, GO:0006096=IEA} glycolysis, pyruvate metabolic process, tricarboxylic acid cycle mitochondrial matrix pyruvate dehydrogenase (acetyl-transferring) activity Human PDHB Reactome UniProtKB {GO:0010510=Reactome:REACT_12528, GO:0006099=PMID:19081061, GO:0006090=Reactome:REACT_2071, GO:0005759=Reactome:REACT_12543, GO:0006006=GO_REF:0000037, GO:0004738=PMID:19081061, GO:0044281=Reactome:REACT_111217, GO:0004739=GO_REF:0000003, GO:0045254=PMID:19081061, GO:0006086=PMID:19081061} P11177 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial protein 20130213 {GO:0010510=TAS, GO:0006099=IDA, GO:0006090=TAS, GO:0005759=TAS, GO:0006006=IEA, GO:0004738=IDA, GO:0044281=TAS, GO:0004739=IEA, GO:0045254=IDA, GO:0006086=IDA} acetyl-CoA biosynthetic process from pyruvate, glucose metabolic process, pyruvate metabolic process, regulation of acetyl-CoA biosynthetic process from pyruvate, small molecule metabolic process, tricarboxylic acid cycle mitochondrial matrix, pyruvate dehydrogenase complex pyruvate dehydrogenase (acetyl-transferring) activity, pyruvate dehydrogenase activity Human PDHX Reactome UniProtKB {GO:0005739=GO_REF:0000019, GO:0010510=Reactome:REACT_12528, GO:0016746=GO_REF:0000002, GO:0006090=Reactome:REACT_2071, GO:0005759=Reactome:REACT_12543, GO:0044281=Reactome:REACT_111217} O00330 Pyruvate dehydrogenase protein X component, mitochondrial protein 20130213 {GO:0005739=IEA, GO:0010510=TAS, GO:0016746=IEA, GO:0006090=TAS, GO:0005759=TAS, GO:0044281=TAS} pyruvate metabolic process, regulation of acetyl-CoA biosynthetic process from pyruvate, small molecule metabolic process mitochondrial matrix, mitochondrion transferase activity, transferring acyl groups Human PDIA2 UniProtKB UniProtKB {GO:0005515=PMID:17474147, GO:0001666=PMID:12095988, GO:0005783=PMID:12095988, GO:0006662=GO_REF:0000002, GO:0015035=GO_REF:0000002, GO:0009055=GO_REF:0000002, GO:0003756=GO_REF:0000003, GO:0006915=PMID:12095988, GO:0006457=PMID:8561901, GO:0005788=GO_REF:0000039, GO:0045454=GO_REF:0000002, GO:0006621=PMID:8561901, GO:0016853=GO_REF:0000038, GO:0005496=GO_REF:0000037} Q4TT65 Protein disulfide isomerase family A, member 2 protein 20130413 {GO:0005515=IPI, GO:0001666=IMP, GO:0005783=IDA, GO:0006662=IEA, GO:0015035=IEA, GO:0009055=IEA, GO:0003756=IEA, GO:0006915=IMP, GO:0006457=TAS, GO:0005788=IEA, GO:0045454=IEA, GO:0006621=TAS, GO:0016853=IEA, GO:0005496=IEA} apoptotic process, cell redox homeostasis, glycerol ether metabolic process, protein folding, protein retention in ER lumen, response to hypoxia endoplasmic reticulum, endoplasmic reticulum lumen electron carrier activity, isomerase activity, protein binding, protein disulfide isomerase activity, protein disulfide oxidoreductase activity, steroid binding Human UniProtKB-KW:KW-0413 PDIA3 HPA UniProtKB {GO:0005515=PMID:17055437, GO:0002474=Reactome:REACT_75820, GO:0042470=GO_REF:0000039, GO:0043065=GO_REF:0000019, GO:0009986=PMID:19995400, GO:0005783=GO_REF:0000052, GO:0006662=GO_REF:0000002, GO:0042590=Reactome:REACT_111119, GO:0015035=GO_REF:0000002, GO:0009055=GO_REF:0000002, GO:0003756=GO_REF:0000003, GO:0006606=PMID:7487104, GO:0004197=PMID:9399589, GO:0007165=PMID:3398923, GO:0004629=PMID:3398923, GO:0006457=Reactome:REACT_23878, GO:0005788=Reactome:REACT_75922, GO:0002479=Reactome:REACT_111178, GO:0045454=GO_REF:0000002, GO:0006621=PMID:9399589, GO:0016853=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} P30101 Protein disulfide-isomerase A3 protein 20080205 {GO:0005515=IPI, GO:0002474=TAS, GO:0042470=IEA, GO:0043065=IEA, GO:0009986=IDA, GO:0005783=IDA, GO:0006662=IEA, GO:0042590=TAS, GO:0015035=IEA, GO:0009055=IEA, GO:0003756=IEA, GO:0006606=TAS, GO:0004197=TAS, GO:0007165=TAS, GO:0004629=TAS, GO:0006457=TAS, GO:0005788=TAS, GO:0002479=TAS, GO:0045454=IEA, GO:0006621=TAS, GO:0016853=IEA, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, cell redox homeostasis, cellular protein metabolic process, glycerol ether metabolic process, positive regulation of apoptotic process, post-translational protein modification, protein N-linked glycosylation via asparagine, protein folding, protein import into nucleus, protein retention in ER lumen, signal transduction cell surface, endoplasmic reticulum, endoplasmic reticulum lumen, melanosome cysteine-type endopeptidase activity, electron carrier activity, isomerase activity, phospholipase C activity, protein binding, protein disulfide isomerase activity, protein disulfide oxidoreductase activity Human PDIA4 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0042470=GO_REF:0000039, GO:0009306=PMID:2295602, GO:0009986=PMID:19995400, GO:0006662=GO_REF:0000002, GO:0015035=GO_REF:0000002, GO:0005788=GO_REF:0000039, GO:0003756=GO_REF:0000003, GO:0009055=GO_REF:0000002, GO:0045454=GO_REF:0000002} P13667 Protein disulfide-isomerase A4 protein 20130415 {GO:0005515=IPI, GO:0042470=IEA, GO:0009306=TAS, GO:0009986=IDA, GO:0006662=IEA, GO:0015035=IEA, GO:0005788=IEA, GO:0003756=IEA, GO:0009055=IEA, GO:0045454=IEA} cell redox homeostasis, glycerol ether metabolic process, protein secretion cell surface, endoplasmic reticulum lumen, melanosome electron carrier activity, protein binding, protein disulfide isomerase activity, protein disulfide oxidoreductase activity Human UniProtKB:Q76353 PDIA5 UniProtKB UniProtKB {GO:0006662=GO_REF:0000002, GO:0006950=GO_REF:0000024, GO:0015035=GO_REF:0000002, GO:0009055=GO_REF:0000002, GO:0003756=PMID:7556671, GO:0030968=Reactome:REACT_18356, GO:0006457=PMID:7556671, GO:0016491=PMID:7556671, GO:0005789=Reactome:REACT_115818, GO:0005788=PMID:7556671, GO:0045454=GO_REF:0000002, GO:0016853=GO_REF:0000038, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0055114=PMID:7556671} Q9BV43 Protein disulfide isomerase family A, member 5, isoform CRA_b protein 20130413 {GO:0006662=IEA, GO:0006950=ISS, GO:0015035=IEA, GO:0009055=IEA, GO:0003756=TAS, GO:0030968=TAS, GO:0006457=TAS, GO:0016491=TAS, GO:0005789=TAS, GO:0005788=TAS, GO:0045454=IEA, GO:0016853=IEA, GO:0006987=TAS, GO:0044267=TAS, GO:0055114=TAS} activation of signaling protein activity involved in unfolded protein response, cell redox homeostasis, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, glycerol ether metabolic process, oxidation-reduction process, protein folding, response to stress endoplasmic reticulum lumen, endoplasmic reticulum membrane electron carrier activity, isomerase activity, oxidoreductase activity, protein disulfide isomerase activity, protein disulfide oxidoreductase activity Human UniProtKB-KW:KW-0413 PDIA6 Reactome UniProtKB {GO:0005515=PMID:15466936, GO:0042470=GO_REF:0000039, GO:0005793=PMID:15308636, GO:0005886=GO_REF:0000039, GO:0005783=PMID:16130169, GO:0006662=GO_REF:0000002, GO:0015035=GO_REF:0000002, GO:0009055=GO_REF:0000002, GO:0003756=GO_REF:0000003, GO:0030968=Reactome:REACT_18356, GO:0006457=PMID:7590364, GO:0005789=Reactome:REACT_116071, GO:0005788=GO_REF:0000039, GO:0045454=GO_REF:0000002, GO:0006987=Reactome:REACT_18368, GO:0016853=GO_REF:0000002, GO:0044267=Reactome:REACT_17015} Q15084 Protein disulfide-isomerase A6 protein 20130301 {GO:0005515=IPI, GO:0042470=IEA, GO:0005793=IDA, GO:0005886=IEA, GO:0005783=TAS, GO:0006662=IEA, GO:0015035=IEA, GO:0009055=IEA, GO:0003756=IEA, GO:0030968=TAS, GO:0006457=TAS, GO:0005789=TAS, GO:0005788=IEA, GO:0045454=IEA, GO:0006987=TAS, GO:0016853=IEA, GO:0044267=TAS} activation of signaling protein activity involved in unfolded protein response, cell redox homeostasis, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, glycerol ether metabolic process, protein folding endoplasmic reticulum, endoplasmic reticulum lumen, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment, melanosome, plasma membrane electron carrier activity, isomerase activity, protein binding, protein disulfide isomerase activity, protein disulfide oxidoreductase activity Human PDIK1L UniProtKB UniProtKB {GO:0004674=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0005524=GO_REF:0000037} Q8N165 Serine/threonine-protein kinase PDIK1L protein 20130413 {GO:0004674=IEA, GO:0005634=IEA, GO:0005524=IEA} nucleus ATP binding, protein serine/threonine kinase activity Human UniProtKB-SubCell:SL-0191 PDILT UniProtKB UniProtKB {GO:0005783=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0045454=GO_REF:0000002, GO:0007283=GO_REF:0000037, GO:0016853=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q8N807 Protein disulfide-isomerase-like protein of the testis protein 20130413 {GO:0005783=IEA, GO:0007275=IEA, GO:0045454=IEA, GO:0007283=IEA, GO:0016853=IEA, GO:0030154=IEA} cell differentiation, cell redox homeostasis, multicellular organismal development, spermatogenesis endoplasmic reticulum isomerase activity Human UniProtKB-SubCell:SL-0095 PDK1 GOC UniProtKB {GO:0004740=PMID:7499431, GO:0010510=Reactome:REACT_12528, GO:0097411=PMID:21763680, GO:0008283=PMID:18541534, GO:0008631=PMID:18541534, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0010906=PMID:18541534, GO:0005739=PMID:7499431, GO:0004672=PMID:17683942, GO:0016301=GO_REF:0000038, GO:0004674=GO_REF:0000037, GO:0006090=Reactome:REACT_2071, GO:0005759=Reactome:REACT_12462, GO:0006006=GO_REF:0000037, GO:0006468=PMID:7499431} Q15118 "Pyruvate dehydrogenase lipoamide"""" kinase isozyme 1, mitochondrial" protein 20130413 {GO:0004740=IDA, GO:0010510=TAS, GO:0097411=IMP, GO:0008283=IMP, GO:0008631=IMP, GO:0044281=TAS, GO:0005524=IEA, GO:0010906=IMP, GO:0005739=TAS, GO:0004672=IDA, GO:0016301=IEA, GO:0004674=IEA, GO:0006090=TAS, GO:0005759=TAS, GO:0006006=IEA, GO:0006468=TAS} cell proliferation, glucose metabolic process, hypoxia-inducible factor-1alpha signaling pathway, intrinsic apoptotic signaling pathway in response to oxidative stress, protein phosphorylation, pyruvate metabolic process, regulation of acetyl-CoA biosynthetic process from pyruvate, regulation of glucose metabolic process, small molecule metabolic process mitochondrial matrix, mitochondrion ATP binding, kinase activity, protein kinase activity, protein serine/threonine kinase activity, pyruvate dehydrogenase (acetyl-transferring) kinase activity Human PDK2 GOC UniProtKB {GO:0008286=GO_REF:0000024, GO:0031670=GO_REF:0000024, GO:0005967=GO_REF:0000024, GO:0010565=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0010906=GO_REF:0000024, GO:0042803=PMID:19833728, GO:0006885=GO_REF:0000024, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0006090=Reactome:REACT_2071, GO:0005759=Reactome:REACT_12462, GO:0006006=GO_REF:0000037, GO:0004740=PMID:19833728, GO:0010510=Reactome:REACT_12528, GO:0005730=GO_REF:0000052, GO:0042593=GO_REF:0000024, GO:0005524=PMID:16401071, GO:0006111=GO_REF:0000024, GO:0004672=PMID:10748134, GO:0072332=PMID:22123926, GO:0004674=GO_REF:0000037, GO:0034614=PMID:21283817, GO:0006468=PMID:7499431} Q15119 "Pyruvate dehydrogenase lipoamide"""" kinase isozyme 2, mitochondrial" protein 20130413 {GO:0008286=ISS, GO:0031670=ISS, GO:0005967=ISS, GO:0010565=ISS, GO:0005634=IDA, GO:0044281=TAS, GO:0010906=ISS, GO:0042803=IPI, GO:0006885=ISS, GO:0005739=IDA, GO:0005737=IDA, GO:0006090=TAS, GO:0005759=TAS, GO:0006006=IEA, GO:0004740=IDA, GO:0010510=TAS, GO:0005730=IDA, GO:0042593=ISS, GO:0005524=IDA, GO:0006111=ISS, GO:0004672=TAS, GO:0072332=IMP, GO:0004674=IEA, GO:0034614=IMP, GO:0006468=TAS} cellular response to nutrient, cellular response to reactive oxygen species, glucose homeostasis, glucose metabolic process, insulin receptor signaling pathway, intrinsic apoptotic signaling pathway by p53 class mediator, protein phosphorylation, pyruvate metabolic process, regulation of acetyl-CoA biosynthetic process from pyruvate, regulation of cellular ketone metabolic process, regulation of gluconeogenesis, regulation of glucose metabolic process, regulation of pH, small molecule metabolic process cytoplasm, mitochondrial matrix, mitochondrial pyruvate dehydrogenase complex, mitochondrion, nucleolus, nucleus ATP binding, protein homodimerization activity, protein kinase activity, protein serine/threonine kinase activity, pyruvate dehydrogenase (acetyl-transferring) kinase activity Human PDK3 Reactome UniProtKB {GO:0005515=PMID:15861126, GO:0004740=PMID:11486000, GO:0010510=Reactome:REACT_12528, GO:0097411=PMID:18718909, GO:0035357=PMID:17669420, GO:0044281=Reactome:REACT_111217, GO:0005524=PMID:15861126, GO:0010906=PMID:22865452, GO:0005739=PMID:7499431, GO:0071398=PMID:20715114, GO:0004672=PMID:15861126, GO:0018105=PMID:11486000, GO:0006090=Reactome:REACT_2071, GO:0004674=PMID:11486000, GO:0005759=Reactome:REACT_12462, GO:0006006=GO_REF:0000037, GO:2000377=PMID:22865452, GO:0071333=GO_REF:0000024} Q15120 "Pyruvate dehydrogenase lipoamide"""" kinase isozyme 3, mitochondrial" protein 20130301 {GO:0005515=IPI, GO:0004740=IDA, GO:0010510=TAS, GO:0097411=IMP, GO:0035357=IMP, GO:0044281=TAS, GO:0005524=IDA, GO:0010906=IMP, GO:0005739=TAS, GO:0071398=IMP, GO:0004672=IDA, GO:0018105=IDA, GO:0006090=TAS, GO:0004674=IDA, GO:0005759=TAS, GO:0006006=IEA, GO:2000377=IMP, GO:0071333=ISS} cellular response to fatty acid, cellular response to glucose stimulus, glucose metabolic process, hypoxia-inducible factor-1alpha signaling pathway, peptidyl-serine phosphorylation, peroxisome proliferator activated receptor signaling pathway, pyruvate metabolic process, regulation of acetyl-CoA biosynthetic process from pyruvate, regulation of glucose metabolic process, regulation of reactive oxygen species metabolic process, small molecule metabolic process mitochondrial matrix, mitochondrion ATP binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, pyruvate dehydrogenase (acetyl-transferring) kinase activity Human PDK4 GOC UniProtKB {GO:0004740=GO_REF:0000024, GO:0008286=PMID:21852536, GO:0010510=Reactome:REACT_12528, GO:0072593=PMID:21852536, GO:0005743=GO_REF:0000019, GO:0010565=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0042593=GO_REF:0000024, GO:0046320=GO_REF:0000024, GO:2000811=PMID:21852536, GO:0005524=PMID:18658136, GO:0006885=GO_REF:0000024, GO:0010906=PMID:21852536, GO:0005739=PMID:8798399, GO:0071398=PMID:20715114, GO:0004672=PMID:18658136, GO:0042594=GO_REF:0000024, GO:0042304=PMID:21852536, GO:0006090=Reactome:REACT_2071, GO:0004674=GO_REF:0000037, GO:0005759=Reactome:REACT_12462, GO:0006006=GO_REF:0000037, GO:0006468=PMID:8798399, GO:0009267=PMID:14966024} Q16654 "Pyruvate dehydrogenase lipoamide"""" kinase isozyme 4, mitochondrial" protein 20130413 {GO:0004740=ISS, GO:0008286=IMP, GO:0010510=TAS, GO:0072593=IMP, GO:0005743=IEA, GO:0010565=ISS, GO:0044281=TAS, GO:0042593=ISS, GO:0046320=ISS, GO:2000811=IMP, GO:0005524=IDA, GO:0006885=ISS, GO:0010906=IMP, GO:0005739=TAS, GO:0071398=IMP, GO:0004672=IDA, GO:0042594=ISS, GO:0042304=IMP, GO:0006090=TAS, GO:0004674=IEA, GO:0005759=TAS, GO:0006006=IEA, GO:0006468=TAS, GO:0009267=IDA} cellular response to fatty acid, cellular response to starvation, glucose homeostasis, glucose metabolic process, insulin receptor signaling pathway, negative regulation of anoikis, protein phosphorylation, pyruvate metabolic process, reactive oxygen species metabolic process, regulation of acetyl-CoA biosynthetic process from pyruvate, regulation of cellular ketone metabolic process, regulation of fatty acid biosynthetic process, regulation of fatty acid oxidation, regulation of glucose metabolic process, regulation of pH, response to starvation, small molecule metabolic process mitochondrial inner membrane, mitochondrial matrix, mitochondrion ATP binding, protein kinase activity, protein serine/threonine kinase activity, pyruvate dehydrogenase (acetyl-transferring) kinase activity Human PDLIM1 PINC UniProtKB {GO:0005667=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0006355=GO_REF:0000019, GO:0003713=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005856=GO_REF:0000039, GO:0006979=PMID:8522188} O00151 PDZ and LIM domain protein 1 protein 20030904 {GO:0005667=IEA, GO:0001666=IEA, GO:0005737=IEA, GO:0006355=IEA, GO:0003713=IEA, GO:0008270=IEA, GO:0005856=IEA, GO:0006979=TAS} regulation of transcription, DNA-dependent, response to hypoxia, response to oxidative stress cytoplasm, cytoskeleton, transcription factor complex transcription coactivator activity, zinc ion binding Human PDLIM2 HPA UniProtKB {GO:0051371=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0009986=PMID:12493773, GO:0031005=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0015629=GO_REF:0000052, GO:0005925=GO_REF:0000052, GO:0032036=GO_REF:0000019} Q96JY6 PDZ and LIM domain protein 2 protein 20100326 {GO:0051371=IEA, GO:0005737=IEA, GO:0009986=IDA, GO:0031005=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0015629=IDA, GO:0005925=IDA, GO:0032036=IEA} actin cytoskeleton, cell surface, cytoplasm, focal adhesion, nucleus filamin binding, muscle alpha-actinin binding, myosin heavy chain binding, zinc ion binding Human PDLIM3 UniProtKB UniProtKB {GO:0008092=GO_REF:0000019, GO:0007507=GO_REF:0000019, GO:0030018=GO_REF:0000039, GO:0007015=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0015629=GO_REF:0000019, GO:0008307=GO_REF:0000019} Q53GG5 PDZ and LIM domain protein 3 protein 20130413 {GO:0008092=IEA, GO:0007507=IEA, GO:0030018=IEA, GO:0007015=IEA, GO:0008270=IEA, GO:0015629=IEA, GO:0008307=IEA} actin filament organization, heart development Z disc, actin cytoskeleton cytoskeletal protein binding, structural constituent of muscle, zinc ion binding Human UniProtKB-SubCell:SL-0314 PDLIM4 UniProtKB UniProtKB {GO:0005515=PMID:10826496, GO:0008270=GO_REF:0000002} P50479 PDZ and LIM domain protein 4 protein 20051118 {GO:0005515=IPI, GO:0008270=IEA} protein binding, zinc ion binding Human UniProtKB:Q15654 PDLIM5 LIFEdb UniProtKB {GO:0030018=GO_REF:0000019, GO:0051963=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000037, GO:0042805=GO_REF:0000024, GO:0014069=GO_REF:0000024, GO:0003779=GO_REF:0000024, GO:0015629=GO_REF:0000054, GO:0005829=GO_REF:0000024, GO:0047485=GO_REF:0000019, GO:0016020=GO_REF:0000024, GO:0045211=GO_REF:0000037, GO:0005080=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0061001=GO_REF:0000024} Q96HC4 PDZ and LIM domain protein 5 protein 20100607 {GO:0030018=IEA, GO:0051963=ISS, GO:0030054=IEA, GO:0005886=IEA, GO:0042805=ISS, GO:0014069=ISS, GO:0003779=ISS, GO:0015629=IDA, GO:0005829=ISS, GO:0047485=IEA, GO:0016020=ISS, GO:0045211=IEA, GO:0005080=ISS, GO:0008270=IEA, GO:0061001=ISS} regulation of dendritic spine morphogenesis, regulation of synapse assembly Z disc, actin cytoskeleton, cell junction, cytosol, membrane, plasma membrane, postsynaptic density, postsynaptic membrane actin binding, actinin binding, protein N-terminus binding, protein kinase C binding, zinc ion binding Human PDLIM7 HPA UniProtKB {GO:0005515=PMID:16713569, GO:0001725=GO_REF:0000019, GO:0030054=GO_REF:0000052, GO:0030036=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0015629=GO_REF:0000052, GO:0001726=GO_REF:0000019, GO:0030154=GO_REF:0000037, GO:0006898=PMID:7929196, GO:0045669=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0001503=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0005925=GO_REF:0000052} Q9NR12 PDZ and LIM domain protein 7 protein 20101115 {GO:0005515=IPI, GO:0001725=IEA, GO:0030054=IDA, GO:0030036=IEA, GO:0007275=IEA, GO:0015629=IDA, GO:0001726=IEA, GO:0030154=IEA, GO:0006898=TAS, GO:0045669=IEA, GO:0005737=IEA, GO:0001503=IEA, GO:0008270=IEA, GO:0005925=IDA} actin cytoskeleton organization, cell differentiation, multicellular organismal development, ossification, positive regulation of osteoblast differentiation, receptor-mediated endocytosis actin cytoskeleton, cell junction, cytoplasm, focal adhesion, ruffle, stress fiber protein binding, zinc ion binding Human PDP1 Reactome UniProtKB {GO:0005739=GO_REF:0000019, GO:0010510=Reactome:REACT_12528, GO:0004741=GO_REF:0000003, GO:0006470=GO_REF:0000002, GO:0006090=Reactome:REACT_2071, GO:0005759=Reactome:REACT_12543, GO:0044281=Reactome:REACT_111217, GO:0004722=PMID:20801214, GO:0046872=GO_REF:0000037} Q9P0J1 "Pyruvate dehydrogenase acetyl-transferring""""-phosphatase 1, mitochondrial" protein 20130213 {GO:0005739=IEA, GO:0010510=TAS, GO:0004741=IEA, GO:0006470=IEA, GO:0006090=TAS, GO:0005759=TAS, GO:0044281=TAS, GO:0004722=IDA, GO:0046872=IEA} protein dephosphorylation, pyruvate metabolic process, regulation of acetyl-CoA biosynthetic process from pyruvate, small molecule metabolic process mitochondrial matrix, mitochondrion "pyruvate dehydrogenase (lipoamide)"" phosphatase activity, metal ion binding, protein serine/threonine phosphatase activity""" Human PDP2 Reactome UniProtKB {GO:0005739=GO_REF:0000019, GO:0010510=Reactome:REACT_12528, GO:0035970=GO_REF:0000019, GO:0004741=GO_REF:0000003, GO:0006090=Reactome:REACT_2071, GO:0005759=Reactome:REACT_12543, GO:0004724=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037} Q9P2J9 "Pyruvate dehydrogenase acetyl-transferring""""-phosphatase 2, mitochondrial" protein 20130213 {GO:0005739=IEA, GO:0010510=TAS, GO:0035970=IEA, GO:0004741=IEA, GO:0006090=TAS, GO:0005759=TAS, GO:0004724=IEA, GO:0044281=TAS, GO:0046872=IEA} peptidyl-threonine dephosphorylation, pyruvate metabolic process, regulation of acetyl-CoA biosynthetic process from pyruvate, small molecule metabolic process mitochondrial matrix, mitochondrion "pyruvate dehydrogenase (lipoamide)"" phosphatase activity, magnesium-dependent protein serine/threonine phosphatase activity, metal ion binding""" Human PDPK1 BHF-UCL UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005515=PMID:21075311, GO:0050852=Reactome:REACT_12526, GO:0030036=PMID:10792047, GO:0005886=Reactome:REACT_147873, GO:0034122=GO_REF:0000019, GO:0005158=GO_REF:0000019, GO:0031295=Reactome:REACT_19344, GO:0007268=Reactome:REACT_13685, GO:0005829=Reactome:REACT_147873, GO:0035556=PMID:14749367, GO:0005737=PMID:9637919, GO:0010594=GO_REF:0000019, GO:0046777=PMID:15209375, GO:0007173=Reactome:REACT_9417, GO:0016301=Reactome:REACT_908, GO:0018107=PMID:9368760, GO:0048041=GO_REF:0000019, GO:0032148=PMID:9368760, GO:0010667=GO_REF:0000019, GO:0043122=PMID:16207722, GO:0030512=PMID:17327236, GO:0043304=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0032869=PMID:10567711, GO:0048011=Reactome:REACT_11061, GO:0019901=GO_REF:0000019, GO:0048015=Reactome:REACT_12464, GO:0030168=Reactome:REACT_798, GO:0042981=PMID:16207722, GO:0003323=GO_REF:0000019, GO:0006972=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0004672=GO_REF:0000002, GO:0008543=Reactome:REACT_9470, GO:0007596=Reactome:REACT_604, GO:0004674=PMID:9368760, GO:0045087=Reactome:REACT_6802, GO:0004676=PMID:9368760, GO:0016023=GO_REF:0000019, GO:0005654=Reactome:REACT_20640, GO:0006468=PMID:14585963, GO:0006469=PMID:9373175, GO:0005925=GO_REF:0000039, GO:0090004=PMID:10567711} O15530 3-phosphoinositide-dependent protein kinase 1 protein 20090227 {GO:0008286=TAS, GO:0005515=IPI, GO:0050852=TAS, GO:0030036=TAS, GO:0005886=TAS, GO:0034122=IEA, GO:0005158=IEA, GO:0031295=TAS, GO:0007268=TAS, GO:0005829=TAS, GO:0035556=IDA, GO:0005737=IDA, GO:0010594=IEA, GO:0046777=TAS, GO:0007173=TAS, GO:0016301=EXP, GO:0018107=IDA, GO:0048041=IEA, GO:0032148=IDA, GO:0010667=IEA, GO:0043122=IMP, GO:0030512=IDA, GO:0043304=IEA, GO:0006355=IEA, GO:0032869=IMP, GO:0048011=TAS, GO:0019901=IEA, GO:0048015=TAS, GO:0030168=TAS, GO:0042981=IMP, GO:0003323=IEA, GO:0006972=IEA, GO:0005524=IEA, GO:0006351=IEA, GO:0004672=IEA, GO:0008543=TAS, GO:0007596=TAS, GO:0004674=IDA, GO:0045087=TAS, GO:0004676=IDA, GO:0016023=IEA, GO:0005654=TAS, GO:0006468=IDA, GO:0006469=IDA, GO:0005925=IEA, GO:0090004=IMP} T cell costimulation, T cell receptor signaling pathway, actin cytoskeleton organization, activation of protein kinase B activity, blood coagulation, cellular response to insulin stimulus, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, focal adhesion assembly, hyperosmotic response, innate immune response, insulin receptor signaling pathway, intracellular signal transduction, negative regulation of cardiac muscle cell apoptotic process, negative regulation of protein kinase activity, negative regulation of toll-like receptor signaling pathway, negative regulation of transforming growth factor beta receptor signaling pathway, neurotrophin TRK receptor signaling pathway, peptidyl-threonine phosphorylation, phosphatidylinositol-mediated signaling, platelet activation, positive regulation of establishment of protein localization to plasma membrane, protein autophosphorylation, protein phosphorylation, regulation of I-kappaB kinase/NF-kappaB cascade, regulation of apoptotic process, regulation of endothelial cell migration, regulation of mast cell degranulation, regulation of transcription, DNA-dependent, synaptic transmission, transcription, DNA-dependent, type B pancreatic cell development cytoplasm, cytoplasmic membrane-bounded vesicle, cytosol, focal adhesion, nucleoplasm, plasma membrane 3-phosphoinositide-dependent protein kinase activity, ATP binding, insulin receptor binding, kinase activity, protein binding, protein kinase activity, protein kinase binding, protein serine/threonine kinase activity Human PDPN PINC UniProtKB {GO:0006693=GO_REF:0000019, GO:0005886=GO_REF:0000024, GO:0030324=GO_REF:0000024, GO:0008283=GO_REF:0000019, GO:0008360=GO_REF:0000037, GO:0015884=GO_REF:0000024, GO:0006865=GO_REF:0000024, GO:0031527=GO_REF:0000039, GO:0006928=GO_REF:0000019, GO:0031528=GO_REF:0000039, GO:0009790=GO_REF:0000019, GO:0030175=GO_REF:0000024, GO:0001946=GO_REF:0000024, GO:0016337=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0006954=GO_REF:0000019, GO:0015171=GO_REF:0000024, GO:0015250=GO_REF:0000024, GO:0010572=GO_REF:0000019, GO:0005372=GO_REF:0000024, GO:0006833=GO_REF:0000024, GO:0030335=GO_REF:0000019, GO:0048286=GO_REF:0000019, GO:0031258=GO_REF:0000039, GO:0032587=GO_REF:0000039, GO:0008517=GO_REF:0000024, GO:0001726=GO_REF:0000024, GO:0030027=GO_REF:0000024, GO:0007399=GO_REF:0000019, GO:0000902=GO_REF:0000024, GO:0007165=GO_REF:0000019, GO:0007049=GO_REF:0000019, GO:0005887=PMID:10393083, GO:0035239=GO_REF:0000019, GO:0055093=GO_REF:0000019, GO:0016021=GO_REF:0000002, GO:0051272=GO_REF:0000024} Q86YL7 Podoplanin protein 20061106 {GO:0006693=IEA, GO:0005886=ISS, GO:0030324=ISS, GO:0008283=IEA, GO:0008360=IEA, GO:0015884=ISS, GO:0006865=ISS, GO:0031527=IEA, GO:0006928=IEA, GO:0031528=IEA, GO:0009790=IEA, GO:0030175=ISS, GO:0001946=ISS, GO:0016337=IEA, GO:0016324=IEA, GO:0006954=IEA, GO:0015171=ISS, GO:0015250=ISS, GO:0010572=IEA, GO:0005372=ISS, GO:0006833=ISS, GO:0030335=IEA, GO:0048286=IEA, GO:0031258=IEA, GO:0032587=IEA, GO:0008517=ISS, GO:0001726=ISS, GO:0030027=ISS, GO:0007399=IEA, GO:0000902=ISS, GO:0007165=IEA, GO:0007049=IEA, GO:0005887=TAS, GO:0035239=IEA, GO:0055093=IEA, GO:0016021=IEA, GO:0051272=ISS} amino acid transport, cell cycle, cell morphogenesis, cell proliferation, cell-cell adhesion, cellular component movement, embryo development, folic acid transport, inflammatory response, lung alveolus development, lung development, lymphangiogenesis, nervous system development, positive regulation of cell migration, positive regulation of cellular component movement, positive regulation of platelet activation, prostaglandin metabolic process, regulation of cell shape, response to hyperoxia, signal transduction, tube morphogenesis, water transport apical plasma membrane, filopodium, filopodium membrane, integral to membrane, integral to plasma membrane, lamellipodium, lamellipodium membrane, microvillus membrane, plasma membrane, ruffle, ruffle membrane amino acid transmembrane transporter activity, folic acid transporter activity, water channel activity, water transmembrane transporter activity Human PDPR Reactome UniProtKB {GO:0005739=GO_REF:0000019, GO:0010510=Reactome:REACT_12528, GO:0005737=GO_REF:0000002, GO:0006090=Reactome:REACT_2071, GO:0005759=Reactome:REACT_12543, GO:0016491=GO_REF:0000002, GO:0006546=GO_REF:0000002, GO:0004047=GO_REF:0000002, GO:0044281=Reactome:REACT_111217} Q8NCN5 Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial protein 20130213 {GO:0005739=IEA, GO:0010510=TAS, GO:0005737=IEA, GO:0006090=TAS, GO:0005759=TAS, GO:0016491=IEA, GO:0006546=IEA, GO:0004047=IEA, GO:0044281=TAS} glycine catabolic process, pyruvate metabolic process, regulation of acetyl-CoA biosynthetic process from pyruvate, small molecule metabolic process cytoplasm, mitochondrial matrix, mitochondrion aminomethyltransferase activity, oxidoreductase activity Human PDRG1 InterPro UniProtKB {GO:0006457=GO_REF:0000002, GO:0016272=GO_REF:0000002, GO:0051082=GO_REF:0000002} Q9NUG6 p53 and DNA damage-regulated protein 1 protein 20130413 {GO:0006457=IEA, GO:0016272=IEA, GO:0051082=IEA} protein folding prefoldin complex unfolded protein binding Human InterPro:IPR002777 PDS5A HPA UniProtKB {GO:0005515=PMID:21111234, GO:0000236=Reactome:REACT_682, GO:0005886=GO_REF:0000052, GO:0005694=Reactome:REACT_150454, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005829=Reactome:REACT_150294, GO:0000084=Reactome:REACT_899, GO:0000910=Reactome:REACT_1932, GO:0000087=Reactome:REACT_910, GO:0005654=Reactome:REACT_150456, GO:0008156=PMID:19907496, GO:0000278=Reactome:REACT_152, GO:0000785=PMID:16682347, GO:0000090=Reactome:REACT_1275, GO:0000775=Reactome:REACT_150445} Q29RF7 Sister chromatid cohesion protein PDS5 homolog A protein 20111111 {GO:0005515=IPI, GO:0000236=TAS, GO:0005886=IDA, GO:0005694=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0005829=TAS, GO:0000084=TAS, GO:0000910=TAS, GO:0000087=TAS, GO:0005654=TAS, GO:0008156=IMP, GO:0000278=TAS, GO:0000785=IDA, GO:0000090=TAS, GO:0000775=TAS} M phase of mitotic cell cycle, S phase of mitotic cell cycle, cytokinesis, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, negative regulation of DNA replication chromatin, chromosome, chromosome, centromeric region, cytosol, nucleolus, nucleoplasm, nucleus, plasma membrane protein binding Human PDS5B HPA UniProtKB {GO:0005515=PMID:21111234, GO:0000236=Reactome:REACT_682, GO:0008285=PMID:10963680, GO:0005694=Reactome:REACT_150454, GO:0008283=PMID:10963680, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000002, GO:0005524=PMID:10215036, GO:0005829=Reactome:REACT_150294, GO:0000084=Reactome:REACT_899, GO:0000910=Reactome:REACT_1932, GO:0042127=PMID:10963680, GO:0000087=Reactome:REACT_910, GO:0005654=Reactome:REACT_150456, GO:0000278=Reactome:REACT_152, GO:0000785=PMID:16682347, GO:0000090=Reactome:REACT_1275, GO:0000775=Reactome:REACT_150445, GO:0007064=PMID:15855230} Q9NTI5 Sister chromatid cohesion protein PDS5 homolog B protein 20110516 {GO:0005515=IPI, GO:0000236=TAS, GO:0008285=IDA, GO:0005694=TAS, GO:0008283=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0005524=TAS, GO:0005829=TAS, GO:0000084=TAS, GO:0000910=TAS, GO:0042127=IDA, GO:0000087=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000785=IDA, GO:0000090=TAS, GO:0000775=TAS, GO:0007064=IMP} M phase of mitotic cell cycle, S phase of mitotic cell cycle, cell proliferation, cytokinesis, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, mitotic sister chromatid cohesion, negative regulation of cell proliferation, regulation of cell proliferation chromatin, chromosome, chromosome, centromeric region, cytosol, nucleolus, nucleoplasm, nucleus ATP binding, DNA binding, protein binding NOT Human PDSS1 Reactome UniProtKB {GO:0050347=GO_REF:0000019, GO:0006744=Reactome:REACT_160111, GO:0000010=PMID:16262699, GO:0046982=PMID:16262699, GO:0005759=Reactome:REACT_160269, GO:0051290=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0008299=PMID:16262699, GO:0046872=GO_REF:0000037, GO:0016740=GO_REF:0000038} Q5T2R2 Decaprenyl-diphosphate synthase subunit 1 protein 20120319 {GO:0050347=IEA, GO:0006744=TAS, GO:0000010=IDA, GO:0046982=IDA, GO:0005759=TAS, GO:0051290=IEA, GO:0044281=TAS, GO:0008299=IDA, GO:0046872=IEA, GO:0016740=IEA} isoprenoid biosynthetic process, protein heterotetramerization, small molecule metabolic process, ubiquinone biosynthetic process mitochondrial matrix metal ion binding, protein heterodimerization activity, trans-hexaprenyltranstransferase activity, trans-octaprenyltranstransferase activity, transferase activity Human PDSS2 HPA UniProtKB {GO:0050347=GO_REF:0000019, GO:0006744=Reactome:REACT_160111, GO:0005737=GO_REF:0000052, GO:0000010=PMID:16262699, GO:0046982=PMID:16262699, GO:0005759=Reactome:REACT_160269, GO:0051290=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0008299=PMID:16262699, GO:0050878=GO_REF:0000019} Q86YH6 Decaprenyl-diphosphate synthase subunit 2 protein 20101115 {GO:0050347=IEA, GO:0006744=TAS, GO:0005737=IDA, GO:0000010=IDA, GO:0046982=IDA, GO:0005759=TAS, GO:0051290=IEA, GO:0044281=TAS, GO:0008299=IDA, GO:0050878=IEA} isoprenoid biosynthetic process, protein heterotetramerization, regulation of body fluid levels, small molecule metabolic process, ubiquinone biosynthetic process cytoplasm, mitochondrial matrix protein heterodimerization activity, trans-hexaprenyltranstransferase activity, trans-octaprenyltranstransferase activity Human PDX1 BHF-UCL UniProtKB {GO:0008284=GO_REF:0000019, GO:0003700=PMID:17941991, GO:0008285=GO_REF:0000019, GO:0007263=PMID:17941991, GO:0006366=GO_REF:0000019, GO:0031100=GO_REF:0000019, GO:0060290=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0006091=PMID:8954967, GO:0032403=GO_REF:0000019, GO:0005829=GO_REF:0000039, GO:0007224=GO_REF:0000019, GO:0003309=GO_REF:0000024, GO:0010260=GO_REF:0000019, GO:0045944=GO_REF:0000024, GO:0010157=GO_REF:0000019, GO:0009887=PMID:8988180, GO:0006006=GO_REF:0000019, GO:0032024=GO_REF:0000019, GO:0001046=GO_REF:0000019, GO:0034097=GO_REF:0000019, GO:0010942=GO_REF:0000019, GO:0043201=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0009611=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0048565=GO_REF:0000019, GO:0042593=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0033273=GO_REF:0000019, GO:0007417=GO_REF:0000019, GO:0048863=GO_REF:0000019, GO:0001889=GO_REF:0000019, GO:0051594=GO_REF:0000024, GO:0070542=GO_REF:0000019, GO:0016331=GO_REF:0000019, GO:0031018=Reactome:REACT_13819, GO:0003682=GO_REF:0000019, GO:0031017=GO_REF:0000019, GO:0043388=GO_REF:0000019, GO:0030073=PMID:17941991, GO:0035094=GO_REF:0000019, GO:0008134=GO_REF:0000019} P52945 Pancreas/duodenum homeobox protein 1 protein 20080228 {GO:0008284=IEA, GO:0003700=TAS, GO:0008285=IEA, GO:0007263=IDA, GO:0006366=IEA, GO:0031100=IEA, GO:0060290=IEA, GO:0005634=IEA, GO:0006091=TAS, GO:0032403=IEA, GO:0005829=IEA, GO:0007224=IEA, GO:0003309=ISS, GO:0010260=IEA, GO:0045944=ISS, GO:0010157=IEA, GO:0009887=TAS, GO:0006006=IEA, GO:0032024=IEA, GO:0001046=IEA, GO:0034097=IEA, GO:0010942=IEA, GO:0043201=IEA, GO:0046982=IEA, GO:0042493=IEA, GO:0009611=IEA, GO:0051384=IEA, GO:0048565=IEA, GO:0042593=IEA, GO:0000122=IEA, GO:0033273=IEA, GO:0007417=IEA, GO:0048863=IEA, GO:0001889=IEA, GO:0051594=ISS, GO:0070542=IEA, GO:0016331=IEA, GO:0031018=TAS, GO:0003682=IEA, GO:0031017=IEA, GO:0043388=IEA, GO:0030073=IDA, GO:0035094=IEA, GO:0008134=IEA} central nervous system development, detection of glucose, digestive tract development, endocrine pancreas development, exocrine pancreas development, generation of precursor metabolites and energy, glucose homeostasis, glucose metabolic process, insulin secretion, liver development, morphogenesis of embryonic epithelium, negative regulation of cell proliferation, negative regulation of transcription from RNA polymerase II promoter, nitric oxide mediated signal transduction, organ morphogenesis, organ regeneration, organ senescence, positive regulation of DNA binding, positive regulation of cell death, positive regulation of cell proliferation, positive regulation of insulin secretion, positive regulation of transcription from RNA polymerase II promoter, response to chlorate, response to cytokine stimulus, response to drug, response to fatty acid, response to glucocorticoid stimulus, response to leucine, response to nicotine, response to vitamin, response to wounding, smoothened signaling pathway, stem cell differentiation, transcription from RNA polymerase II promoter, transdifferentiation, type B pancreatic cell differentiation cytosol, nucleus chromatin binding, core promoter sequence-specific DNA binding, protein complex binding, protein heterodimerization activity, sequence-specific DNA binding transcription factor activity, transcription factor binding Human PDXDC1 InterPro UniProtKB {GO:0030170=GO_REF:0000002, GO:0016831=GO_REF:0000002, GO:0019752=GO_REF:0000002} Q86XE2 PDXDC1 protein protein 20130413 {GO:0030170=IEA, GO:0016831=IEA, GO:0019752=IEA} carboxylic acid metabolic process carboxy-lyase activity, pyridoxal phosphate binding Human InterPro:IPR002129|InterPro:IPR015421|InterPro:IPR015422 PDXK HPA UniProtKB {GO:0042823=PMID:9099727, GO:0000287=PMID:17766369, GO:0008283=PMID:10930737, GO:0042816=Reactome:REACT_25012, GO:0005730=GO_REF:0000052, GO:0006767=Reactome:REACT_11238, GO:0008478=Reactome:REACT_25323, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0030955=PMID:17766369, GO:0031402=PMID:17766369, GO:0031403=PMID:9252787, GO:0005524=PMID:17766369, GO:0042803=PMID:17766369, GO:0005829=Reactome:REACT_25323, GO:0005737=GO_REF:0000052, GO:0006766=Reactome:REACT_11193, GO:0030170=PMID:16600635, GO:0008270=PMID:10987144, GO:0009443=GO_REF:0000002} O00764 Pyridoxal kinase protein 20111111 {GO:0042823=IDA, GO:0000287=IDA, GO:0008283=IDA, GO:0042816=TAS, GO:0005730=IDA, GO:0006767=TAS, GO:0008478=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0030955=IDA, GO:0031402=IDA, GO:0031403=IDA, GO:0005524=IDA, GO:0042803=IDA, GO:0005829=TAS, GO:0005737=IDA, GO:0006766=TAS, GO:0030170=IDA, GO:0008270=IDA, GO:0009443=IEA} cell proliferation, pyridoxal 5'-phosphate salvage, pyridoxal phosphate biosynthetic process, small molecule metabolic process, vitamin B6 metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cytoplasm, cytosol, nucleolus, nucleus ATP binding, lithium ion binding, magnesium ion binding, potassium ion binding, protein homodimerization activity, pyridoxal kinase activity, pyridoxal phosphate binding, sodium ion binding, zinc ion binding Human PDXP IntAct UniProtKB {GO:0005515=PMID:17500066, GO:0007088=PMID:15580268, GO:0032465=PMID:15580268, GO:0005886=PMID:15580268, GO:0031258=GO_REF:0000039, GO:0031247=PMID:19000834, GO:0030496=PMID:15580268, GO:0032587=PMID:15580268, GO:0015629=PMID:15580268, GO:0032154=PMID:15580268, GO:0004647=GO_REF:0000003, GO:0030027=PMID:15580268, GO:0071318=PMID:19000834, GO:0046872=GO_REF:0000037, GO:0005829=PMID:15580268, GO:0006470=PMID:15580268, GO:0031072=PMID:19000834, GO:0030836=PMID:15580268, GO:0004721=PMID:19000834, GO:0033883=GO_REF:0000003, GO:0070938=PMID:15580268} Q96GD0 Pyridoxal phosphate phosphatase protein 20130415 {GO:0005515=IPI, GO:0007088=IMP, GO:0032465=IMP, GO:0005886=IDA, GO:0031258=IEA, GO:0031247=IDA, GO:0030496=IDA, GO:0032587=IDA, GO:0015629=IDA, GO:0032154=IDA, GO:0004647=IEA, GO:0030027=IDA, GO:0071318=IDA, GO:0046872=IEA, GO:0005829=IDA, GO:0006470=IDA, GO:0031072=IDA, GO:0030836=IMP, GO:0004721=IDA, GO:0033883=IEA, GO:0070938=IDA} actin rod assembly, cellular response to ATP, positive regulation of actin filament depolymerization, protein dephosphorylation, regulation of cytokinesis, regulation of mitosis actin cytoskeleton, cleavage furrow, contractile ring, cytosol, lamellipodium, lamellipodium membrane, midbody, plasma membrane, ruffle membrane heat shock protein binding, metal ion binding, phosphoprotein phosphatase activity, phosphoserine phosphatase activity, protein binding, pyridoxal phosphatase activity Human UniProtKB:P29066 PDYN Reactome UniProtKB {GO:0008219=GO_REF:0000037, GO:0005886=PMID:9047294, GO:0007218=GO_REF:0000037, GO:0001515=GO_REF:0000037, GO:0007268=GO_REF:0000037, GO:0005576=Reactome:REACT_22289} P01213 Proenkephalin-B protein 20080730 {GO:0008219=IEA, GO:0005886=IDA, GO:0007218=IEA, GO:0001515=IEA, GO:0007268=IEA, GO:0005576=TAS} cell death, neuropeptide signaling pathway, synaptic transmission extracellular region, plasma membrane opioid peptide activity Human PDZD11 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q5EBL8 PDZ domain-containing protein 11 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 PDZD2 UniProtKB UniProtKB {GO:0005737=PMID:11289102, GO:0005911=PMID:12671685, GO:0005783=PMID:12671685, GO:0005576=PMID:12671685, GO:0005634=PMID:12671685, GO:0007155=GO_REF:0000037} O15018 PDZ domain-containing protein 2 protein 20050218 {GO:0005737=IDA, GO:0005911=ISS, GO:0005783=ISS, GO:0005576=ISS, GO:0005634=ISS, GO:0007155=IEA} cell adhesion cell-cell junction, cytoplasm, endoplasmic reticulum, extracellular region, nucleus Human UniProtKB:Q9QZR8 PDZD3 GOC UniProtKB {GO:0005515=PMID:15523054, GO:0030251=PMID:11950846, GO:0045177=PMID:11950846, GO:0009636=PMID:11950846, GO:0019934=PMID:11950846, GO:0008022=PMID:19088451, GO:0005829=PMID:11950846, GO:0005903=PMID:19088451, GO:0031283=PMID:11950846, GO:0030827=PMID:11950846, GO:0006833=PMID:11950846, GO:0008200=PMID:11950846, GO:0035003=PMID:19088451, GO:0007168=PMID:11950846, GO:0006811=PMID:11950846} Q86UT5 Na(+)/H(+) exchange regulatory cofactor NHE-RF4 protein 20130413 {GO:0005515=IPI, GO:0030251=IDA, GO:0045177=IDA, GO:0009636=TAS, GO:0019934=NAS, GO:0008022=IPI, GO:0005829=TAS, GO:0005903=IDA, GO:0031283=IDA, GO:0030827=TAS, GO:0006833=NAS, GO:0008200=TAS, GO:0035003=IDA, GO:0007168=IC, GO:0006811=NAS} cGMP-mediated signaling, ion transport, negative regulation of cGMP biosynthetic process, negative regulation of guanylate cyclase activity, receptor guanylyl cyclase signaling pathway, response to toxic substance, water transport apical part of cell, brush border, cytosol, subapical complex guanylate cyclase inhibitor activity, ion channel inhibitor activity, protein C-terminus binding, protein binding Human PDZD4 UniProtKB UniProtKB {GO:0005938=GO_REF:0000039} Q76G19 PDZ domain-containing protein 4 protein 20130413 {GO:0005938=IEA} cell cortex Human UniProtKB-SubCell:SL-0138 PDZD8 UniProtKB UniProtKB {GO:0035556=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0022604=PMID:21834987, GO:0007010=PMID:21834987, GO:0046872=GO_REF:0000037} Q8NEN9 PDZ domain-containing protein 8 protein 20110926 {GO:0035556=IEA, GO:0019048=IEA, GO:0022604=IMP, GO:0007010=IMP, GO:0046872=IEA} cytoskeleton organization, intracellular signal transduction, regulation of cell morphogenesis, virus-host interaction metal ion binding Human PDZD9 null null {} null null null null {} null null null PDZK1 BHF-UCL UniProtKB {GO:0005515=PMID:15304510, GO:0005215=PMID:9461128, GO:0005737=GO_REF:0000039, GO:0008283=PMID:9461128, GO:0006810=PMID:15523054, GO:0031526=PMID:15523054, GO:0015879=PMID:15523054, GO:0034767=PMID:15523054, GO:0015893=PMID:16738539, GO:0030165=PMID:16236806, GO:0005124=GO_REF:0000019, GO:0090002=GO_REF:0000019} Q5T2W1 Na(+)/H(+) exchange regulatory cofactor NHE-RF3 protein 20100309 {GO:0005515=IPI, GO:0005215=TAS, GO:0005737=IEA, GO:0008283=TAS, GO:0006810=IDA, GO:0031526=ISS, GO:0015879=IDA, GO:0034767=IDA, GO:0015893=NAS, GO:0030165=IPI, GO:0005124=IEA, GO:0090002=IEA} carnitine transport, cell proliferation, drug transport, establishment of protein localization to plasma membrane, positive regulation of ion transmembrane transport, transport brush border membrane, cytoplasm PDZ domain binding, protein binding, scavenger receptor binding, transporter activity Human UniProtKB:Q96S37 PDZK1IP1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q13113 PDZK1-interacting protein 1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 PDZRN3 UniProtKB UniProtKB {GO:0004842=GO_REF:0000024, GO:0016567=GO_REF:0000024, GO:0031594=GO_REF:0000019, GO:0007528=GO_REF:0000019, GO:0008270=GO_REF:0000002} Q9UPQ7 E3 ubiquitin-protein ligase PDZRN3 protein 20100706 {GO:0004842=ISS, GO:0016567=ISS, GO:0031594=IEA, GO:0007528=IEA, GO:0008270=IEA} neuromuscular junction development, protein ubiquitination neuromuscular junction ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q69ZS0 PDZRN4 InterPro UniProtKB {GO:0004842=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q6ZMN7 PDZ domain-containing RING finger protein 4 protein 20130413 {GO:0004842=IEA, GO:0008270=IEA} ubiquitin-protein ligase activity, zinc ion binding Human InterPro:IPR001841|InterPro:IPR013323 PEA15 PINC UniProtKB {GO:0005515=PMID:10442631, GO:0043066=PMID:10442631, GO:0005737=GO_REF:0000039, GO:0005875=PMID:8662970, GO:0046325=PMID:9670003, GO:0006810=PMID:9670003, GO:0008643=GO_REF:0000037, GO:0006915=GO_REF:0000037, GO:0043278=GO_REF:0000019, GO:0042981=PMID:10442631} Q15121 Astrocytic phosphoprotein PEA-15 protein 20050308 {GO:0005515=IPI, GO:0043066=IDA, GO:0005737=IEA, GO:0005875=NAS, GO:0046325=IDA, GO:0006810=TAS, GO:0008643=IEA, GO:0006915=IEA, GO:0043278=IEA, GO:0042981=IDA} apoptotic process, carbohydrate transport, negative regulation of apoptotic process, negative regulation of glucose import, regulation of apoptotic process, response to morphine, transport cytoplasm, microtubule associated complex protein binding Human PEBP1 PINC UniProtKB {GO:0005737=GO_REF:0000039, GO:0008429=PMID:7637590, GO:0004867=GO_REF:0000037, GO:0005524=GO_REF:0000037} P30086 Phosphatidylethanolamine-binding protein 1 protein 20030904 {GO:0005737=IEA, GO:0008429=TAS, GO:0004867=IEA, GO:0005524=IEA} cytoplasm ATP binding, phosphatidylethanolamine binding, serine-type endopeptidase inhibitor activity Human PEBP4 UniProtKB UniProtKB {GO:0005764=GO_REF:0000039} Q96S96 Phosphatidylethanolamine-binding protein 4 protein 20130413 {GO:0005764=IEA} lysosome Human UniProtKB-SubCell:SL-0158 PECAM1 BHF-UCL UniProtKB {GO:0005515=PMID:18672896, GO:0006909=PMID:12110892, GO:0008037=PMID:1690453, GO:0030054=GO_REF:0000039, GO:0005886=Reactome:REACT_23942, GO:0030168=Reactome:REACT_798, GO:0050900=Reactome:REACT_12051, GO:0005615=PMID:9290466, GO:0050904=PMID:19342684, GO:0007165=PMID:7994021, GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0031092=Reactome:REACT_21394, GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037} P16284 Platelet endothelial cell adhesion molecule protein 20080623 {GO:0005515=IPI, GO:0006909=IDA, GO:0008037=TAS, GO:0030054=IEA, GO:0005886=TAS, GO:0030168=TAS, GO:0050900=TAS, GO:0005615=IDA, GO:0050904=IDA, GO:0007165=TAS, GO:0007596=TAS, GO:0002576=TAS, GO:0031092=TAS, GO:0016021=IEA, GO:0007155=IEA} blood coagulation, cell adhesion, cell recognition, diapedesis, leukocyte migration, phagocytosis, platelet activation, platelet degranulation, signal transduction cell junction, extracellular space, integral to membrane, plasma membrane, platelet alpha granule membrane protein binding Human PECR HPA UniProtKB {GO:0005739=GO_REF:0000019, GO:0008670=PMID:11669066, GO:0019166=PMID:16546181, GO:0005102=PMID:11669066, GO:0016491=GO_REF:0000002, GO:0006633=GO_REF:0000041, GO:0033306=PMID:16546181, GO:0005778=PMID:10811639, GO:0043231=GO_REF:0000052, GO:0005777=PMID:11669066, GO:0055114=PMID:16546181} Q9BY49 Peroxisomal trans-2-enoyl-CoA reductase protein 20100326 {GO:0005739=IEA, GO:0008670=IDA, GO:0019166=IDA, GO:0005102=IPI, GO:0016491=IEA, GO:0006633=IEA, GO:0033306=IDA, GO:0005778=ISS, GO:0043231=IDA, GO:0005777=IDA, GO:0055114=IDA} fatty acid biosynthetic process, oxidation-reduction process, phytol metabolic process intracellular membrane-bounded organelle, mitochondrion, peroxisomal membrane, peroxisome 2,4-dienoyl-CoA reductase (NADPH) activity, oxidoreductase activity, receptor binding, trans-2-enoyl-CoA reductase (NADPH) activity Human PEF1 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0051592=PMID:11278427, GO:0005737=PMID:11278427, GO:0046982=PMID:11278427, GO:0016020=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0046983=PMID:11883899} Q9UBV8 Peflin protein 20130415 {GO:0005515=IPI, GO:0051592=IPI, GO:0005737=IDA, GO:0046982=IPI, GO:0016020=IEA, GO:0005509=IEA, GO:0046983=IPI} response to calcium ion cytoplasm, membrane calcium ion binding, protein binding, protein dimerization activity, protein heterodimerization activity Human UniProtKB:Q15038 PEG10 HPA UniProtKB {GO:0005515=PMID:21903422, GO:0005737=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0001890=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0030512=PMID:15611116, GO:0030154=GO_REF:0000037} Q86TG7 Retrotransposon-derived protein PEG10 protein 20120912 {GO:0005515=IPI, GO:0005737=IDA, GO:0006915=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0001890=IEA, GO:0003677=IEA, GO:0030512=IDA, GO:0030154=IEA} apoptotic process, cell differentiation, negative regulation of transforming growth factor beta receptor signaling pathway, placenta development cytoplasm, nucleus DNA binding, protein binding, zinc ion binding Human PEG3 GOC UniProtKB {GO:0006357=GO_REF:0000033, GO:0006366=GO_REF:0000033, GO:0000981=GO_REF:0000033, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0001701=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0035264=GO_REF:0000019, GO:0071514=GO_REF:0000019, GO:0016032=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q9GZU2 Paternally-expressed gene 3 protein protein 20130413 {GO:0006357=IBA, GO:0006366=IBA, GO:0000981=IBA, GO:0005730=IDA, GO:0006915=IEA, GO:0005634=IDA, GO:0003676=IEA, GO:0001701=IEA, GO:0005737=IDA, GO:0035264=IEA, GO:0071514=IEA, GO:0016032=IEA, GO:0008270=IEA} apoptotic process, genetic imprinting, in utero embryonic development, multicellular organism growth, regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter, viral reproduction cytoplasm, nucleolus, nucleus nucleic acid binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, zinc ion binding Human PANTHER:PTN000003381 PELI1 Reactome UniProtKB {GO:0034145=GO_REF:0000019, GO:0043331=GO_REF:0000019, GO:0004842=GO_REF:0000019, GO:0034142=Reactome:REACT_6894, GO:0034141=GO_REF:0000019, GO:0030890=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0001819=GO_REF:0000019, GO:0042130=GO_REF:0000019, GO:0005829=Reactome:REACT_25241, GO:0002755=Reactome:REACT_27215, GO:0032496=GO_REF:0000019, GO:0031398=GO_REF:0000019, GO:0043123=Reactome:REACT_24918, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0032088=GO_REF:0000019, GO:0002224=Reactome:REACT_9020, GO:0008063=GO_REF:0000002, GO:0045087=Reactome:REACT_6802, GO:0034166=Reactome:REACT_9027, GO:0070936=GO_REF:0000019, GO:0034146=Reactome:REACT_9061, GO:0034162=Reactome:REACT_9047} Q96FA3 E3 ubiquitin-protein ligase pellino homolog 1 protein 20130301 {GO:0034145=IEA, GO:0043331=IEA, GO:0004842=IEA, GO:0034142=TAS, GO:0034141=IEA, GO:0030890=IEA, GO:0005634=IEA, GO:0001819=IEA, GO:0042130=IEA, GO:0005829=TAS, GO:0002755=TAS, GO:0032496=IEA, GO:0031398=IEA, GO:0043123=TAS, GO:0038124=TAS, GO:0038123=TAS, GO:0034134=TAS, GO:0032088=IEA, GO:0002224=TAS, GO:0008063=IEA, GO:0045087=TAS, GO:0034166=TAS, GO:0070936=IEA, GO:0034146=TAS, GO:0034162=TAS} MyD88-dependent toll-like receptor signaling pathway, Toll signaling pathway, innate immune response, negative regulation of NF-kappaB transcription factor activity, negative regulation of T cell proliferation, positive regulation of B cell proliferation, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of cytokine production, positive regulation of protein ubiquitination, positive regulation of toll-like receptor 3 signaling pathway, positive regulation of toll-like receptor 4 signaling pathway, protein K48-linked ubiquitination, response to dsRNA, response to lipopolysaccharide, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway cytosol, nucleus ubiquitin-protein ligase activity Human PELI2 IntAct UniProtKB {GO:0005515=PMID:12860405, GO:0038124=Reactome:REACT_8006, GO:0016567=GO_REF:0000041, GO:0034142=Reactome:REACT_6894, GO:0038123=Reactome:REACT_8005, GO:0016874=GO_REF:0000037, GO:0034134=Reactome:REACT_7980, GO:0002224=Reactome:REACT_9020, GO:0005829=Reactome:REACT_25241, GO:0008063=GO_REF:0000002, GO:0045087=Reactome:REACT_6802, GO:0002755=Reactome:REACT_27215, GO:0001934=PMID:12804775, GO:0034166=Reactome:REACT_9027, GO:0043123=Reactome:REACT_24918, GO:0043410=PMID:12804775, GO:0034146=Reactome:REACT_9061, GO:0034162=Reactome:REACT_9047} Q9HAT8 E3 ubiquitin-protein ligase pellino homolog 2 protein 20130415 {GO:0005515=IPI, GO:0038124=TAS, GO:0016567=IEA, GO:0034142=TAS, GO:0038123=TAS, GO:0016874=IEA, GO:0034134=TAS, GO:0002224=TAS, GO:0005829=TAS, GO:0008063=IEA, GO:0045087=TAS, GO:0002755=TAS, GO:0001934=IDA, GO:0034166=TAS, GO:0043123=TAS, GO:0043410=IDA, GO:0034146=TAS, GO:0034162=TAS} MyD88-dependent toll-like receptor signaling pathway, Toll signaling pathway, innate immune response, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of MAPK cascade, positive regulation of protein phosphorylation, protein ubiquitination, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway cytosol ligase activity, protein binding Human UniProtKB:Q9NWZ3 PELI3 Reactome UniProtKB {GO:0008063=GO_REF:0000002, GO:0016567=GO_REF:0000041, GO:0016874=GO_REF:0000037, GO:0005829=Reactome:REACT_22325} Q8N2H9 E3 ubiquitin-protein ligase pellino homolog 3 protein 20091217 {GO:0008063=IEA, GO:0016567=IEA, GO:0016874=IEA, GO:0005829=TAS} Toll signaling pathway, protein ubiquitination cytosol ligase activity Human PELO UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0051276=GO_REF:0000019, GO:0007049=GO_REF:0000037, GO:0004519=GO_REF:0000037, GO:0008283=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0046872=GO_REF:0000037, GO:0051301=GO_REF:0000037} Q9BRX2 Protein pelota homolog protein 20130413 {GO:0005737=IEA, GO:0051276=IEA, GO:0007049=IEA, GO:0004519=IEA, GO:0008283=IEA, GO:0005634=IEA, GO:0046872=IEA, GO:0051301=IEA} cell cycle, cell division, cell proliferation, chromosome organization cytoplasm, nucleus endonuclease activity, metal ion binding Human UniProtKB-SubCell:SL-0086 PELP1 IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0005737=GO_REF:0000039, GO:0071339=PMID:15960975, GO:0006351=GO_REF:0000037} Q8IZL8 Proline-, glutamic acid- and leucine-rich protein 1 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0071339=IDA, GO:0006351=IEA} transcription, DNA-dependent MLL1 complex, cytoplasm protein binding Human UniProtKB:P19838 PEMT Reactome UniProtKB {GO:0006629=PMID:9989271, GO:0031966=GO_REF:0000039, GO:0008283=PMID:9989271, GO:0044281=Reactome:REACT_111217, GO:0008170=GO_REF:0000002, GO:0080101=GO_REF:0000003, GO:0005789=Reactome:REACT_121126, GO:0004608=GO_REF:0000003, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0000773=GO_REF:0000003, GO:0006656=Reactome:REACT_121238, GO:0046474=Reactome:REACT_121401} Q9UBM1 Phosphatidylethanolamine N-methyltransferase protein 20130301 {GO:0006629=TAS, GO:0031966=IEA, GO:0008283=TAS, GO:0044281=TAS, GO:0008170=IEA, GO:0080101=IEA, GO:0005789=TAS, GO:0004608=IEA, GO:0016021=IEA, GO:0006644=TAS, GO:0000773=IEA, GO:0006656=TAS, GO:0046474=TAS} cell proliferation, glycerophospholipid biosynthetic process, lipid metabolic process, phosphatidylcholine biosynthetic process, phospholipid metabolic process, small molecule metabolic process endoplasmic reticulum membrane, integral to membrane, mitochondrial membrane N-methyltransferase activity, phosphatidyl-N-dimethylethanolamine N-methyltransferase activity, phosphatidyl-N-methylethanolamine N-methyltransferase activity, phosphatidylethanolamine N-methyltransferase activity Human PENK Reactome UniProtKB {GO:0007165=PMID:7057924, GO:0007218=GO_REF:0000037, GO:0001515=GO_REF:0000037, GO:0005576=Reactome:REACT_22289, GO:0001662=GO_REF:0000019, GO:0005184=PMID:7057924, GO:0019233=GO_REF:0000019} P01210 Proenkephalin-A protein 20080730 {GO:0007165=TAS, GO:0007218=IEA, GO:0001515=IEA, GO:0005576=TAS, GO:0001662=IEA, GO:0005184=TAS, GO:0019233=IEA} behavioral fear response, neuropeptide signaling pathway, sensory perception of pain, signal transduction extracellular region neuropeptide hormone activity, opioid peptide activity Human PEPD PINC UniProtKB {GO:0006520=PMID:1972707, GO:0030145=GO_REF:0000002, GO:0016787=GO_REF:0000038, GO:0009987=GO_REF:0000002, GO:0004177=GO_REF:0000002, GO:0030574=GO_REF:0000037, GO:0006508=GO_REF:0000037, GO:0016805=GO_REF:0000037, GO:0004181=PMID:1972707} P12955 Xaa-Pro dipeptidase protein 20030904 {GO:0006520=TAS, GO:0030145=IEA, GO:0016787=IEA, GO:0009987=IEA, GO:0004177=IEA, GO:0030574=IEA, GO:0006508=IEA, GO:0016805=IEA, GO:0004181=TAS} cellular amino acid metabolic process, cellular process, collagen catabolic process, proteolysis aminopeptidase activity, dipeptidase activity, hydrolase activity, manganese ion binding, metallocarboxypeptidase activity Human PER1 BHF-UCL UniProtKB {GO:0000988=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0070888=PMID:18411297, GO:0000122=GO_REF:0000024, GO:0000978=PMID:18411297, GO:0006351=GO_REF:0000037, GO:0032922=PMID:18411297, GO:0005737=GO_REF:0000039, GO:0009649=PMID:9323128, GO:0007623=PMID:9333243, GO:0009416=GO_REF:0000019, GO:0004871=GO_REF:0000002, GO:0045892=GO_REF:0000024} O15534 Period circadian protein homolog 1 protein 20111105 {GO:0000988=ISS, GO:0005634=IEA, GO:0070888=IDA, GO:0000122=ISS, GO:0000978=IDA, GO:0006351=IEA, GO:0032922=IDA, GO:0005737=IEA, GO:0009649=TAS, GO:0007623=TAS, GO:0009416=IEA, GO:0004871=IEA, GO:0045892=ISS} circadian regulation of gene expression, circadian rhythm, entrainment of circadian clock, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, response to light stimulus, transcription, DNA-dependent cytoplasm, nucleus E-box binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, protein binding transcription factor activity, signal transducer activity Human UniProtKB:O35973 PER2 BHF-UCL UniProtKB {GO:0000988=GO_REF:0000024, GO:0048471=GO_REF:0000039, GO:0005737=GO_REF:0000019, GO:0007623=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0004871=GO_REF:0000002, GO:0000122=GO_REF:0000024, GO:0006351=GO_REF:0000037} O15055 Period circadian protein homolog 2 protein 20111105 {GO:0000988=ISS, GO:0048471=IEA, GO:0005737=IEA, GO:0007623=IEA, GO:0005634=IEA, GO:0004871=IEA, GO:0000122=ISS, GO:0006351=IEA} circadian rhythm, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, nucleus, perinuclear region of cytoplasm protein binding transcription factor activity, signal transducer activity Human UniProtKB:Q9Z301 PER3 ENSEMBL UniProtKB {GO:0005737=GO_REF:0000039, GO:0007623=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0000122=GO_REF:0000019, GO:0004871=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q8TAR6 Period circadian protein homolog 3 protein 20130413 {GO:0005737=IEA, GO:0007623=IEA, GO:0005634=IEA, GO:0000122=IEA, GO:0004871=IEA, GO:0006351=IEA} circadian rhythm, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, nucleus signal transducer activity Human Ensembl:ENSMUSP00000099493 PES1 IntAct UniProtKB {GO:0005515=PMID:16043514, GO:0000463=PMID:16738141, GO:0000793=GO_REF:0000019, GO:0033365=GO_REF:0000019, GO:0008283=PMID:16738141, GO:0006364=PMID:16738141, GO:0042254=GO_REF:0000002, GO:0005730=PMID:16738141, GO:0007000=GO_REF:0000019, GO:0070545=PMID:16738141, GO:0000089=GO_REF:0000019, GO:0051726=PMID:16738141, GO:0042273=PMID:17353269, GO:0005654=PMID:16738141, GO:0030687=PMID:17353269, GO:0000466=PMID:16738141} O00541 Pescadillo homolog protein 20130415 {GO:0005515=IPI, GO:0000463=IMP, GO:0000793=IEA, GO:0033365=IEA, GO:0008283=IMP, GO:0006364=IMP, GO:0042254=IEA, GO:0005730=IDA, GO:0007000=IEA, GO:0070545=IDA, GO:0000089=IEA, GO:0051726=IMP, GO:0042273=IC, GO:0005654=IDA, GO:0030687=IDA, GO:0000466=IMP} cell proliferation, maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), mitotic metaphase, nucleolus organization, protein localization to organelle, rRNA processing, regulation of cell cycle, ribosomal large subunit biogenesis, ribosome biogenesis PeBoW complex, condensed chromosome, nucleolus, nucleoplasm, preribosome, large subunit precursor protein binding Human UniProtKB:Q14137 PET100 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0016021=GO_REF:0000037} P0DJ07 Protein PET100 homolog, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0016021=IEA} integral to membrane, mitochondrion Human UniProtKB-SubCell:SL-0173 PET112 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0032543=PMID:19805282, GO:0016884=GO_REF:0000002, GO:0050567=PMID:19805282, GO:0070681=PMID:19805282, GO:0030956=PMID:19805282, GO:0006412=PMID:9878253, GO:0005524=GO_REF:0000037, GO:0008135=PMID:9878253, GO:0016740=GO_REF:0000038} O75879 Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial protein 20110516 {GO:0005739=IDA, GO:0032543=IMP, GO:0016884=IEA, GO:0050567=IDA, GO:0070681=IDA, GO:0030956=IDA, GO:0006412=TAS, GO:0005524=IEA, GO:0008135=TAS, GO:0016740=IEA} glutaminyl-tRNAGln biosynthesis via transamidation, mitochondrial translation, translation glutamyl-tRNA(Gln) amidotransferase complex, mitochondrion ATP binding, carbon-nitrogen ligase activity, with glutamine as amido-N-donor, glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity, transferase activity, translation factor activity, nucleic acid binding Human PET117 UniProtKB UniProtKB {GO:0005739=PMID:22356826} Q6UWS5 Protein PET117 homolog, mitochondrial protein 20120503 {GO:0005739=IDA} mitochondrion Human PEX1 HPA UniProtKB {GO:0005515=PMID:9588209, GO:0006625=PMID:11439091, GO:0042623=PMID:16854980, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008022=PMID:16854980, GO:0005524=PMID:16854980, GO:0032403=PMID:16854980, GO:0043231=GO_REF:0000052, GO:0005829=PMID:16854980, GO:0005737=GO_REF:0000052, GO:0007031=PMID:11439091, GO:0016558=PMID:9398847, GO:0060152=PMID:16449325, GO:0005778=PMID:21525035, GO:0005777=PMID:16854980} O43933 Peroxisome biogenesis factor 1 protein 20101115 {GO:0005515=IPI, GO:0006625=IMP, GO:0042623=IMP, GO:0005730=IDA, GO:0005634=IDA, GO:0008022=IPI, GO:0005524=IMP, GO:0032403=IDA, GO:0043231=IDA, GO:0005829=IDA, GO:0005737=IDA, GO:0007031=IMP, GO:0016558=IMP, GO:0060152=IMP, GO:0005778=IDA, GO:0005777=IDA} microtubule-based peroxisome localization, peroxisome organization, protein import into peroxisome matrix, protein targeting to peroxisome cytoplasm, cytosol, intracellular membrane-bounded organelle, nucleolus, nucleus, peroxisomal membrane, peroxisome ATP binding, ATPase activity, coupled, protein C-terminus binding, protein binding, protein complex binding Human PEX10 MGI UniProtKB {GO:0005515=PMID:10837480, GO:0007031=PMID:9700193, GO:0008270=GO_REF:0000002, GO:0016558=PMID:9683594, GO:0005779=GO_REF:0000002, GO:0005778=GO_REF:0000019, GO:0005777=PMID:9922452} O60683 Peroxisome biogenesis factor 10 protein 20070604 {GO:0005515=IPI, GO:0007031=IDA, GO:0008270=IEA, GO:0016558=IDA, GO:0005779=IEA, GO:0005778=IEA, GO:0005777=IDA} peroxisome organization, protein import into peroxisome matrix integral to peroxisomal membrane, peroxisomal membrane, peroxisome protein binding, zinc ion binding Human PEX11A Reactome UniProtKB {GO:0005515=PMID:20826455, GO:0044281=Reactome:REACT_111217, GO:0044375=PMID:20826455, GO:0042803=PMID:20826455, GO:0007165=PMID:9792670, GO:0043234=PMID:20826455, GO:0050873=GO_REF:0000019, GO:0007031=PMID:9792670, GO:0005779=PMID:9792670, GO:0016557=GO_REF:0000019, GO:0005778=Reactome:REACT_115962, GO:0044255=Reactome:REACT_22279, GO:0016559=PMID:20826455, GO:0005777=PMID:9922452} O75192 Peroxisomal membrane protein 11A protein 20130301 {GO:0005515=IPI, GO:0044281=TAS, GO:0044375=IDA, GO:0042803=IDA, GO:0007165=IMP, GO:0043234=IDA, GO:0050873=IEA, GO:0007031=IMP, GO:0005779=IDA, GO:0016557=IEA, GO:0005778=TAS, GO:0044255=TAS, GO:0016559=IDA, GO:0005777=IDA} brown fat cell differentiation, cellular lipid metabolic process, peroxisome fission, peroxisome membrane biogenesis, peroxisome organization, regulation of peroxisome size, signal transduction, small molecule metabolic process integral to peroxisomal membrane, peroxisomal membrane, peroxisome, protein complex protein binding, protein homodimerization activity Human PEX11B IntAct UniProtKB {GO:0005515=PMID:14709540, GO:0005739=GO_REF:0000019, GO:0043234=PMID:17408615, GO:0007165=GO_REF:0000024, GO:0007031=PMID:9792670, GO:0051260=PMID:17408615, GO:0005779=PMID:9792670, GO:0042803=PMID:20826455, GO:0005778=PMID:14709540, GO:0044375=PMID:20826455, GO:0005777=PMID:9922452, GO:0016559=PMID:20826455} O96011 Peroxisomal membrane protein 11B protein 20130415 {GO:0005515=IPI, GO:0005739=IEA, GO:0043234=IDA, GO:0007165=ISS, GO:0007031=IDA, GO:0051260=IDA, GO:0005779=IDA, GO:0042803=IDA, GO:0005778=IDA, GO:0044375=IDA, GO:0005777=IDA, GO:0016559=IDA} peroxisome fission, peroxisome organization, protein homooligomerization, regulation of peroxisome size, signal transduction integral to peroxisomal membrane, mitochondrion, peroxisomal membrane, peroxisome, protein complex protein binding, protein homodimerization activity Human UniProtKB:P40855 PEX11G UniProtKB UniProtKB {GO:0005515=PMID:20826455, GO:0043234=PMID:20826455, GO:0031231=PMID:12559946, GO:0005779=GO_REF:0000002, GO:0044375=PMID:20826455, GO:0005777=PMID:20826455, GO:0016559=PMID:20826455} Q96HA9 Peroxisomal membrane protein 11C protein 20120905 {GO:0005515=IPI, GO:0043234=IDA, GO:0031231=IDA, GO:0005779=IEA, GO:0044375=IDA, GO:0005777=IDA, GO:0016559=IDA} peroxisome fission, regulation of peroxisome size integral to peroxisomal membrane, intrinsic to peroxisomal membrane, peroxisome, protein complex protein binding Human PEX12 IntAct UniProtKB {GO:0005515=PMID:10704444, GO:0006625=PMID:12096124, GO:0007031=PMID:17534573, GO:0008270=PMID:10562279, GO:0016558=PMID:12456682, GO:0008022=PMID:10562279, GO:0005779=PMID:10562279, GO:0005778=PMID:21525035, GO:0005777=PMID:9922452} O00623 Peroxisome assembly protein 12 protein 20130415 {GO:0005515=IPI, GO:0006625=NAS, GO:0007031=IMP, GO:0008270=IMP, GO:0016558=NAS, GO:0008022=IPI, GO:0005779=TAS, GO:0005778=IDA, GO:0005777=IDA} peroxisome organization, protein import into peroxisome matrix, protein targeting to peroxisome integral to peroxisomal membrane, peroxisomal membrane, peroxisome protein C-terminus binding, protein binding, zinc ion binding Human UniProtKB:P40855 PEX13 IntAct UniProtKB {GO:0005515=PMID:10704444, GO:0001967=GO_REF:0000024, GO:0021795=GO_REF:0000024, GO:0001561=GO_REF:0000024, GO:0016560=PMID:8858165, GO:0007626=GO_REF:0000024, GO:0001764=GO_REF:0000024, GO:0060152=GO_REF:0000024, GO:0005779=PMID:8858165, GO:0005778=PMID:16449325, GO:0005777=PMID:11829486} Q92968 Peroxisomal membrane protein PEX13 protein 20130415 {GO:0005515=IPI, GO:0001967=ISS, GO:0021795=ISS, GO:0001561=ISS, GO:0016560=IMP, GO:0007626=ISS, GO:0001764=ISS, GO:0060152=ISS, GO:0005779=IDA, GO:0005778=IDA, GO:0005777=IDA} cerebral cortex cell migration, fatty acid alpha-oxidation, locomotory behavior, microtubule-based peroxisome localization, neuron migration, protein import into peroxisome matrix, docking, suckling behavior integral to peroxisomal membrane, peroxisomal membrane, peroxisome protein binding Human UniProtKB:P40855 PEX14 IntAct UniProtKB {GO:0008017=PMID:21525035, GO:0005515=PMID:21525035, GO:0034453=PMID:21525035, GO:0016561=PMID:21525035, GO:0003714=PMID:11863372, GO:0048487=PMID:21525035, GO:0005102=PMID:21525035, GO:1901094=PMID:21976670, GO:0005634=PMID:11863372, GO:0043433=PMID:11863372, GO:0005622=PMID:21976670, GO:0043234=PMID:19584060, GO:0006461=PMID:21525035, GO:0047485=PMID:11863372, GO:0007031=PMID:10022913, GO:0051260=PMID:12488033, GO:0016021=GO_REF:0000024, GO:0016558=PMID:15146459, GO:0045892=PMID:11863372, GO:0005778=PMID:16449325, GO:0005777=PMID:21375735} O75381 Peroxisomal membrane protein PEX14 protein 20130415 {GO:0008017=IDA, GO:0005515=IPI, GO:0034453=IDA, GO:0016561=IDA, GO:0003714=IDA, GO:0048487=IPI, GO:0005102=IPI, GO:1901094=IDA, GO:0005634=NAS, GO:0043433=IDA, GO:0005622=IDA, GO:0043234=IDA, GO:0006461=IDA, GO:0047485=IPI, GO:0007031=IGI, GO:0051260=IDA, GO:0016021=ISS, GO:0016558=IMP, GO:0045892=IDA, GO:0005778=IDA, GO:0005777=IDA} microtubule anchoring, negative regulation of protein homotetramerization, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription, DNA-dependent, peroxisome organization, protein complex assembly, protein homooligomerization, protein import into peroxisome matrix, protein import into peroxisome matrix, translocation integral to membrane, intracellular, nucleus, peroxisomal membrane, peroxisome, protein complex beta-tubulin binding, microtubule binding, protein N-terminus binding, protein binding, receptor binding, transcription corepressor activity Human UniProtKB:P40855 PEX16 MGI UniProtKB {GO:0005515=PMID:19114594, GO:0006625=PMID:9837814, GO:0005783=PMID:21768384, GO:0045046=PMID:12223482, GO:0008022=PMID:15713480, GO:0032581=PMID:16717127, GO:0005789=PMID:16717127, GO:0007031=PMID:19479899, GO:0016558=PMID:9922452, GO:0005779=PMID:9922452, GO:0016557=PMID:12223482, GO:0005778=PMID:21525035, GO:0005777=PMID:21768384} Q9Y5Y5 Peroxisomal membrane protein PEX16 protein 20070604 {GO:0005515=IPI, GO:0006625=IMP, GO:0005783=IDA, GO:0045046=IMP, GO:0008022=IPI, GO:0032581=IDA, GO:0005789=IDA, GO:0007031=IMP, GO:0016558=IMP, GO:0005779=IMP, GO:0016557=IMP, GO:0005778=IDA, GO:0005777=IDA} ER-dependent peroxisome organization, peroxisome membrane biogenesis, peroxisome organization, protein import into peroxisome matrix, protein import into peroxisome membrane, protein targeting to peroxisome endoplasmic reticulum, endoplasmic reticulum membrane, integral to peroxisomal membrane, peroxisomal membrane, peroxisome protein C-terminus binding, protein binding Human PEX19 InterPro UniProtKB {GO:0005515=PMID:11402059, GO:0006625=PMID:10704444, GO:0045046=PMID:11402059, GO:0031526=GO_REF:0000024, GO:0055085=Reactome:REACT_15518, GO:0005829=Reactome:REACT_15396, GO:0036105=PMID:14709540, GO:0043234=PMID:18174172, GO:0005737=PMID:20171429, GO:0047485=PMID:19197237, GO:0007031=PMID:14709540, GO:0051117=PMID:11453642, GO:0072321=PMID:11402059, GO:0005778=PMID:21525035, GO:0005777=GO_REF:0000002, GO:0016559=PMID:18782765} Q5QNY5 Peroxisomal biogenesis factor 19 protein 20130413 {GO:0005515=IPI, GO:0006625=IMP, GO:0045046=IDA, GO:0031526=ISS, GO:0055085=TAS, GO:0005829=TAS, GO:0036105=IDA, GO:0043234=IDA, GO:0005737=IDA, GO:0047485=IPI, GO:0007031=IMP, GO:0051117=IPI, GO:0072321=IDA, GO:0005778=IDA, GO:0005777=IEA, GO:0016559=IMP} chaperone-mediated protein transport, peroxisome fission, peroxisome organization, protein import into peroxisome membrane, protein targeting to peroxisome, transmembrane transport brush border membrane, cytoplasm, cytosol, peroxisomal membrane, peroxisome, protein complex ATPase binding, peroxisome membrane class-1 targeting sequence binding, protein N-terminus binding, protein binding Human InterPro:IPR006708 PEX2 UniProtKB UniProtKB {GO:0042632=GO_REF:0000019, GO:0005515=PMID:11590176, GO:0000038=PMID:9765053, GO:0006635=PMID:10528859, GO:0006699=GO_REF:0000019, GO:0045540=GO_REF:0000019, GO:0048147=PMID:18987311, GO:0050680=PMID:18987311, GO:0007031=PMID:9765053, GO:0016593=PMID:18987311, GO:0008270=GO_REF:0000002, GO:0016558=PMID:10528859, GO:0001764=GO_REF:0000019, GO:0005779=PMID:12751901, GO:0005778=PMID:21525035} P28328 Peroxisome biogenesis factor 2 protein 20120530 {GO:0042632=IEA, GO:0005515=IPI, GO:0000038=IMP, GO:0006635=IMP, GO:0006699=IEA, GO:0045540=IEA, GO:0048147=IMP, GO:0050680=IMP, GO:0007031=IMP, GO:0016593=IDA, GO:0008270=IEA, GO:0016558=IMP, GO:0001764=IEA, GO:0005779=IMP, GO:0005778=IDA} bile acid biosynthetic process, cholesterol homeostasis, fatty acid beta-oxidation, negative regulation of epithelial cell proliferation, negative regulation of fibroblast proliferation, neuron migration, peroxisome organization, protein import into peroxisome matrix, regulation of cholesterol biosynthetic process, very long-chain fatty acid metabolic process Cdc73/Paf1 complex, integral to peroxisomal membrane, peroxisomal membrane protein binding, zinc ion binding Human PEX26 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0051117=PMID:16257970, GO:0045046=GO_REF:0000002, GO:0008022=PMID:15713480, GO:0016558=PMID:15858711, GO:0032403=PMID:16854980, GO:0005779=GO_REF:0000002, GO:0005777=PMID:16763195} Q7Z412 Peroxisome assembly protein 26 protein 20130415 {GO:0005515=IPI, GO:0051117=IPI, GO:0045046=IEA, GO:0008022=IPI, GO:0016558=IMP, GO:0032403=IDA, GO:0005779=IEA, GO:0005777=IDA} protein import into peroxisome matrix, protein import into peroxisome membrane integral to peroxisomal membrane, peroxisome ATPase binding, protein C-terminus binding, protein binding, protein complex binding Human UniProtKB:Q9UMX1 PEX3 InterPro UniProtKB {GO:0005515=PMID:16280322, GO:0005783=PMID:21768384, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0045046=PMID:15007061, GO:0055085=Reactome:REACT_15518, GO:0043231=GO_REF:0000052, GO:0005829=GO_REF:0000019, GO:0008289=PMID:19715730, GO:0043234=PMID:18174172, GO:0032994=PMID:19715730, GO:0046983=PMID:19715730, GO:0007031=GO_REF:0000002, GO:0016557=GO_REF:0000019, GO:0005779=GO_REF:0000002, GO:0005778=Reactome:REACT_15396, GO:0005777=PMID:9922452} Q7Z6V3 Peroxisomal biogenesis factor 3 protein 20130413 {GO:0005515=IPI, GO:0005783=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0045046=IMP, GO:0055085=TAS, GO:0043231=IDA, GO:0005829=IEA, GO:0008289=IDA, GO:0043234=IDA, GO:0032994=IDA, GO:0046983=IDA, GO:0007031=IEA, GO:0016557=IEA, GO:0005779=IEA, GO:0005778=TAS, GO:0005777=IDA} peroxisome membrane biogenesis, peroxisome organization, protein import into peroxisome membrane, transmembrane transport cytosol, endoplasmic reticulum, integral to peroxisomal membrane, intracellular membrane-bounded organelle, nucleolus, nucleus, peroxisomal membrane, peroxisome, protein complex, protein-lipid complex lipid binding, protein binding, protein dimerization activity Human InterPro:IPR006966 PEX5 HPA UniProtKB {GO:0005515=PMID:10562279, GO:0000038=GO_REF:0000019, GO:0031267=PMID:18346465, GO:0045046=PMID:14709540, GO:0005739=GO_REF:0000019, GO:0050905=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0021795=GO_REF:0000019, GO:0007031=GO_REF:0000019, GO:0048468=GO_REF:0000019, GO:0040018=GO_REF:0000019, GO:0016558=PMID:11463335, GO:0005778=PMID:21525035, GO:0021895=GO_REF:0000019, GO:0005777=PMID:11829486, GO:0006635=GO_REF:0000019, GO:0005794=GO_REF:0000052, GO:0000268=PMID:18346465, GO:0043234=PMID:19584060, GO:0047485=PMID:19197237, GO:0016020=PMID:10514471, GO:0005052=PMID:20178365, GO:0007006=GO_REF:0000019, GO:0001764=GO_REF:0000019, GO:0019899=PMID:21976670, GO:0007029=GO_REF:0000019} P50542 Peroxisomal targeting signal 1 receptor protein 20110516 {GO:0005515=IPI, GO:0000038=IEA, GO:0031267=IPI, GO:0045046=IMP, GO:0005739=IEA, GO:0050905=IEA, GO:0005737=IDA, GO:0021795=IEA, GO:0007031=IEA, GO:0048468=IEA, GO:0040018=IEA, GO:0016558=IMP, GO:0005778=IDA, GO:0021895=IEA, GO:0005777=IDA, GO:0006635=IEA, GO:0005794=IDA, GO:0000268=IDA, GO:0043234=IDA, GO:0047485=IPI, GO:0016020=IDA, GO:0005052=IPI, GO:0007006=IEA, GO:0001764=IEA, GO:0019899=IPI, GO:0007029=IEA} cell development, cerebral cortex cell migration, cerebral cortex neuron differentiation, endoplasmic reticulum organization, fatty acid beta-oxidation, mitochondrial membrane organization, neuromuscular process, neuron migration, peroxisome organization, positive regulation of multicellular organism growth, protein import into peroxisome matrix, protein import into peroxisome membrane, very long-chain fatty acid metabolic process Golgi apparatus, cytoplasm, membrane, mitochondrion, peroxisomal membrane, peroxisome, protein complex enzyme binding, peroxisome matrix targeting signal-1 binding, peroxisome targeting sequence binding, protein N-terminus binding, protein binding, small GTPase binding Human PEX5L UniProtKB UniProtKB {GO:0005737=GO_REF:0000019, GO:0031267=PMID:18346465, GO:0016560=GO_REF:0000033, GO:0043949=GO_REF:0000024, GO:0000268=PMID:18346465, GO:0005052=GO_REF:0000033, GO:0042391=GO_REF:0000019, GO:0016558=GO_REF:0000033, GO:0005778=GO_REF:0000033, GO:0045185=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0005829=GO_REF:0000033} Q8IYB4 PEX5-related protein protein 20120614 {GO:0005737=IEA, GO:0031267=IPI, GO:0016560=IBA, GO:0043949=ISS, GO:0000268=IDA, GO:0005052=IBA, GO:0042391=IEA, GO:0016558=IBA, GO:0005778=IBA, GO:0045185=IEA, GO:0030425=IEA, GO:0005829=IBA} maintenance of protein location, protein import into peroxisome matrix, protein import into peroxisome matrix, docking, regulation of cAMP-mediated signaling, regulation of membrane potential cytoplasm, cytosol, dendrite, peroxisomal membrane peroxisome matrix targeting signal-1 binding, peroxisome targeting sequence binding, small GTPase binding Human PEX6 UniProtKB UniProtKB {GO:0005515=PMID:9588209, GO:0017111=GO_REF:0000002, GO:0006200=PMID:8670792, GO:0006625=PMID:16854980, GO:0042623=PMID:16854980, GO:0016561=PMID:8670792, GO:0050821=PMID:8670792, GO:0008022=PMID:16854980, GO:0032403=PMID:16854980, GO:0005524=GO_REF:0000038, GO:0005829=PMID:16854980, GO:0005737=PMID:8670792, GO:0007031=PMID:8940266, GO:0016887=PMID:8670792, GO:0005778=GO_REF:0000039, GO:0005777=PMID:11439091} Q8WYQ0 Peroxin Pex6p protein 20130413 {GO:0005515=IPI, GO:0017111=IEA, GO:0006200=IMP, GO:0006625=IMP, GO:0042623=IMP, GO:0016561=IMP, GO:0050821=IMP, GO:0008022=IPI, GO:0032403=IDA, GO:0005524=IEA, GO:0005829=IDA, GO:0005737=IDA, GO:0007031=IMP, GO:0016887=IMP, GO:0005778=IEA, GO:0005777=IDA} ATP catabolic process, peroxisome organization, protein import into peroxisome matrix, translocation, protein stabilization, protein targeting to peroxisome cytoplasm, cytosol, peroxisomal membrane, peroxisome ATP binding, ATPase activity, ATPase activity, coupled, nucleoside-triphosphatase activity, protein C-terminus binding, protein binding, protein complex binding Human UniProtKB-KW:KW-0067 PEX7 MGI UniProtKB {GO:0001958=GO_REF:0000019, GO:0006635=GO_REF:0000019, GO:0008611=PMID:12522768, GO:0005053=PMID:11931631, GO:0007031=PMID:10022913, GO:0019899=PMID:11931631, GO:0016558=PMID:9090381, GO:0001764=GO_REF:0000019, GO:0042803=PMID:11931631, GO:0005777=PMID:9090382} O00628 Peroxisomal targeting signal 2 receptor protein 20070605 {GO:0001958=IEA, GO:0006635=IEA, GO:0008611=IMP, GO:0005053=IDA, GO:0007031=IMP, GO:0019899=IPI, GO:0016558=IDA, GO:0001764=IEA, GO:0042803=IDA, GO:0005777=IDA} endochondral ossification, ether lipid biosynthetic process, fatty acid beta-oxidation, neuron migration, peroxisome organization, protein import into peroxisome matrix peroxisome enzyme binding, peroxisome matrix targeting signal-2 binding, protein homodimerization activity Human PF4 BHF-UCL UniProtKB {GO:0008009=PMID:12466273, GO:0043066=PMID:10666185, GO:0032760=PMID:10666185, GO:0010744=PMID:17244792, GO:0030595=PMID:6945600, GO:0019221=PMID:12041672, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_22289, GO:0045651=PMID:10666185, GO:0005615=GO_REF:0000037, GO:0010628=PMID:10666185, GO:0045653=PMID:2140694, GO:0006955=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0045918=PMID:10666185, GO:0045347=PMID:10666185, GO:0016525=PMID:1688470, GO:0002576=Reactome:REACT_318, GO:0031093=Reactome:REACT_21351, GO:0008201=PMID:9531587} P02776 Platelet factor 4 protein 20090114 {GO:0008009=TAS, GO:0043066=IDA, GO:0032760=IDA, GO:0010744=IDA, GO:0030595=IDA, GO:0019221=IDA, GO:0030168=TAS, GO:0005576=TAS, GO:0045651=IDA, GO:0005615=IEA, GO:0010628=IDA, GO:0045653=IDA, GO:0006955=IEA, GO:0007596=TAS, GO:0045918=IDA, GO:0045347=IDA, GO:0016525=IDA, GO:0002576=TAS, GO:0031093=TAS, GO:0008201=IDA} blood coagulation, cytokine-mediated signaling pathway, immune response, leukocyte chemotaxis, negative regulation of MHC class II biosynthetic process, negative regulation of angiogenesis, negative regulation of apoptotic process, negative regulation of cytolysis, negative regulation of megakaryocyte differentiation, platelet activation, platelet degranulation, positive regulation of gene expression, positive regulation of macrophage derived foam cell differentiation, positive regulation of macrophage differentiation, positive regulation of tumor necrosis factor production extracellular region, extracellular space, platelet alpha granule lumen chemokine activity, heparin binding Human PF4V1 UniProtKB UniProtKB {GO:0008009=GO_REF:0000002, GO:0006955=GO_REF:0000002, GO:0030595=GO_REF:0000002, GO:0030168=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0008201=GO_REF:0000037} P10720 Platelet factor 4 variant protein 20130413 {GO:0008009=IEA, GO:0006955=IEA, GO:0030595=IEA, GO:0030168=IEA, GO:0005576=IEA, GO:0008201=IEA} immune response, leukocyte chemotaxis, platelet activation extracellular region chemokine activity, heparin binding Human UniProtKB-SubCell:SL-0243 PFAS Reactome UniProtKB {GO:0004642=PMID:10548741, GO:0005737=GO_REF:0000029, GO:0009168=Reactome:REACT_1776, GO:0006144=Reactome:REACT_522, GO:0042493=GO_REF:0000019, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0009156=GO_REF:0000019, GO:0005829=Reactome:REACT_1427, GO:0006541=GO_REF:0000019, GO:0006189=PMID:10548741} O15067 Phosphoribosylformylglycinamidine synthase protein 20130301 {GO:0004642=IDA, GO:0005737=NAS, GO:0009168=TAS, GO:0006144=TAS, GO:0042493=IEA, GO:0055086=TAS, GO:0044281=TAS, GO:0005524=IEA, GO:0009156=IEA, GO:0005829=TAS, GO:0006541=IEA, GO:0006189=NAS} 'de novo' IMP biosynthetic process, glutamine metabolic process, nucleobase-containing small molecule metabolic process, purine nucleobase metabolic process, purine ribonucleoside monophosphate biosynthetic process, response to drug, ribonucleoside monophosphate biosynthetic process, small molecule metabolic process cytoplasm, cytosol ATP binding, phosphoribosylformylglycinamidine synthase activity Human PFDN1 GOC UniProtKB {GO:0042113=GO_REF:0000019, GO:0006355=PMID:8744932, GO:0007049=PMID:8744932, GO:0003700=PMID:8744932, GO:0030036=GO_REF:0000019, GO:0006457=Reactome:REACT_17004, GO:0016272=GO_REF:0000002, GO:0051084=Reactome:REACT_16952, GO:0021549=GO_REF:0000019, GO:0051082=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0021537=GO_REF:0000019} O60925 Prefoldin subunit 1 protein 20130413 {GO:0042113=IEA, GO:0006355=TAS, GO:0007049=TAS, GO:0003700=TAS, GO:0030036=IEA, GO:0006457=TAS, GO:0016272=IEA, GO:0051084=TAS, GO:0021549=IEA, GO:0051082=IEA, GO:0044267=TAS, GO:0021537=IEA} 'de novo' posttranslational protein folding, B cell activation, actin cytoskeleton organization, cell cycle, cellular protein metabolic process, cerebellum development, protein folding, regulation of transcription, DNA-dependent, telencephalon development prefoldin complex sequence-specific DNA binding transcription factor activity, unfolded protein binding Human PFDN2 Reactome UniProtKB {GO:0005515=PMID:17936702, GO:0005739=PMID:17936702, GO:0005737=PMID:17936702, GO:0006457=Reactome:REACT_17004, GO:0016272=PMID:9630229, GO:0051084=Reactome:REACT_16952, GO:0005634=PMID:17936702, GO:0051082=PMID:9630229, GO:0044267=Reactome:REACT_17015} Q9UHV9 Prefoldin subunit 2 protein 20130213 {GO:0005515=IPI, GO:0005739=IDA, GO:0005737=IDA, GO:0006457=TAS, GO:0016272=NAS, GO:0051084=TAS, GO:0005634=IDA, GO:0051082=NAS, GO:0044267=TAS} 'de novo' posttranslational protein folding, cellular protein metabolic process, protein folding cytoplasm, mitochondrion, nucleus, prefoldin complex protein binding, unfolded protein binding Human PFDN4 Reactome UniProtKB {GO:0005515=PMID:17936702, GO:0005739=PMID:17936702, GO:0005737=PMID:17936702, GO:0006457=Reactome:REACT_17004, GO:0016272=GO_REF:0000002, GO:0051087=PMID:9630229, GO:0051084=Reactome:REACT_16952, GO:0005634=PMID:17936702, GO:0051082=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0005829=PMID:9630229} Q9NQP4 Prefoldin subunit 4 protein 20130213 {GO:0005515=IPI, GO:0005739=IDA, GO:0005737=IDA, GO:0006457=TAS, GO:0016272=IEA, GO:0051087=TAS, GO:0051084=TAS, GO:0005634=IDA, GO:0051082=IEA, GO:0044267=TAS, GO:0005829=NAS} 'de novo' posttranslational protein folding, cellular protein metabolic process, protein folding cytoplasm, cytosol, mitochondrion, nucleus, prefoldin complex chaperone binding, protein binding, unfolded protein binding Human PFDN5 BHF-UCL UniProtKB {GO:0005515=PMID:17728244, GO:0006355=PMID:9792694, GO:0060041=GO_REF:0000019, GO:0016272=GO_REF:0000002, GO:0003714=PMID:9792694, GO:0005634=GO_REF:0000039, GO:0005737=PMID:16130169, GO:0006457=Reactome:REACT_17004, GO:0051084=Reactome:REACT_16952, GO:0051082=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0045892=PMID:18281035, GO:0090090=PMID:18281035} Q99471 Prefoldin subunit 5 protein 20100722 {GO:0005515=IPI, GO:0006355=TAS, GO:0060041=IEA, GO:0016272=IEA, GO:0003714=TAS, GO:0005634=IEA, GO:0005737=TAS, GO:0006457=TAS, GO:0051084=TAS, GO:0051082=IEA, GO:0044267=TAS, GO:0045892=IMP, GO:0090090=IMP} 'de novo' posttranslational protein folding, cellular protein metabolic process, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of transcription, DNA-dependent, protein folding, regulation of transcription, DNA-dependent, retina development in camera-type eye cytoplasm, nucleus, prefoldin complex protein binding, transcription corepressor activity, unfolded protein binding Human PFDN6 Reactome UniProtKB {GO:0006457=Reactome:REACT_17004, GO:0016272=PMID:9630229, GO:0051087=PMID:9630229, GO:0051084=Reactome:REACT_16952, GO:0051082=PMID:9630229, GO:0051131=PMID:9630229, GO:0044267=Reactome:REACT_17015} O15212 Prefoldin subunit 6 protein 20130213 {GO:0006457=TAS, GO:0016272=IDA, GO:0051087=IDA, GO:0051084=TAS, GO:0051082=NAS, GO:0051131=IDA, GO:0044267=TAS} 'de novo' posttranslational protein folding, cellular protein metabolic process, chaperone-mediated protein complex assembly, protein folding prefoldin complex chaperone binding, unfolded protein binding Human PFKFB1 InterPro UniProtKB {GO:0005515=PMID:11522786, GO:0031100=GO_REF:0000019, GO:0006094=Reactome:REACT_1520, GO:0044281=Reactome:REACT_111217, GO:0051591=GO_REF:0000019, GO:0006096=Reactome:REACT_1383, GO:0007243=Reactome:REACT_1525, GO:0042802=GO_REF:0000019, GO:0005829=Reactome:REACT_1084, GO:0042594=GO_REF:0000019, GO:0004331=GO_REF:0000002, GO:0033762=GO_REF:0000019, GO:0006006=Reactome:REACT_723, GO:0019900=GO_REF:0000019, GO:0006003=GO_REF:0000002, GO:0003873=GO_REF:0000002, GO:0006000=GO_REF:0000002, GO:0032868=GO_REF:0000019, GO:0005975=Reactome:REACT_474, GO:0070095=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0033133=GO_REF:0000019, GO:0005524=GO_REF:0000002, GO:0006112=Reactome:REACT_1505, GO:0043540=PMID:12379646} Q4VBA9 PFKFB1 protein protein 20130413 {GO:0005515=IPI, GO:0031100=IEA, GO:0006094=TAS, GO:0044281=TAS, GO:0051591=IEA, GO:0006096=TAS, GO:0007243=TAS, GO:0042802=IEA, GO:0005829=TAS, GO:0042594=IEA, GO:0004331=IEA, GO:0033762=IEA, GO:0006006=TAS, GO:0019900=IEA, GO:0006003=IEA, GO:0003873=IEA, GO:0006000=IEA, GO:0032868=IEA, GO:0005975=TAS, GO:0070095=IEA, GO:0051384=IEA, GO:0033133=IEA, GO:0005524=IEA, GO:0006112=TAS, GO:0043540=IDA} carbohydrate metabolic process, energy reserve metabolic process, fructose 2,6-bisphosphate metabolic process, fructose metabolic process, gluconeogenesis, glucose metabolic process, glycolysis, intracellular protein kinase cascade, organ regeneration, positive regulation of glucokinase activity, response to cAMP, response to glucagon stimulus, response to glucocorticoid stimulus, response to insulin stimulus, response to starvation, small molecule metabolic process 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 complex, cytosol 6-phosphofructo-2-kinase activity, ATP binding, fructose-2,6-bisphosphate 2-phosphatase activity, fructose-6-phosphate binding, identical protein binding, kinase binding, protein binding Human InterPro:IPR003094|InterPro:IPR016260 PFKFB2 Reactome UniProtKB {GO:0005515=PMID:8387495, GO:0006089=GO_REF:0000019, GO:0019901=PMID:11069105, GO:0005975=Reactome:REACT_474, GO:0033133=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0006096=Reactome:REACT_1383, GO:0005829=Reactome:REACT_291, GO:0009749=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0006090=GO_REF:0000019, GO:0004331=GO_REF:0000003, GO:0006007=GO_REF:0000019, GO:0006006=Reactome:REACT_723, GO:0032024=GO_REF:0000019, GO:0006003=GO_REF:0000002, GO:0019900=GO_REF:0000019, GO:0003873=PMID:11069105, GO:0006000=GO_REF:0000002} O60825 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 protein 20130213 {GO:0005515=IPI, GO:0006089=IEA, GO:0019901=IPI, GO:0005975=TAS, GO:0033133=IEA, GO:0044281=TAS, GO:0005524=IEA, GO:0006096=TAS, GO:0005829=TAS, GO:0009749=IEA, GO:0005737=IEA, GO:0006090=IEA, GO:0004331=IEA, GO:0006007=IEA, GO:0006006=TAS, GO:0032024=IEA, GO:0006003=IEA, GO:0019900=IEA, GO:0003873=IDA, GO:0006000=IEA} carbohydrate metabolic process, fructose 2,6-bisphosphate metabolic process, fructose metabolic process, glucose catabolic process, glucose metabolic process, glycolysis, lactate metabolic process, positive regulation of glucokinase activity, positive regulation of insulin secretion, pyruvate metabolic process, response to glucose stimulus, small molecule metabolic process cytoplasm, cytosol 6-phosphofructo-2-kinase activity, ATP binding, fructose-2,6-bisphosphate 2-phosphatase activity, kinase binding, protein binding, protein kinase binding Human PFKFB3 UniProtKB UniProtKB {GO:0005975=Reactome:REACT_474, GO:0004331=GO_REF:0000002, GO:0006006=Reactome:REACT_723, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0006003=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0006096=Reactome:REACT_1383, GO:0003873=GO_REF:0000003, GO:0005829=Reactome:REACT_291, GO:0006000=GO_REF:0000002} Q9H178 6-phosphofructo-2-kinase protein 20130413 {GO:0005975=TAS, GO:0004331=IEA, GO:0006006=TAS, GO:0044281=TAS, GO:0003824=IEA, GO:0006003=IEA, GO:0005524=IEA, GO:0006096=TAS, GO:0003873=IEA, GO:0005829=TAS, GO:0006000=IEA} carbohydrate metabolic process, fructose 2,6-bisphosphate metabolic process, fructose metabolic process, glucose metabolic process, glycolysis, small molecule metabolic process cytosol 6-phosphofructo-2-kinase activity, ATP binding, catalytic activity, fructose-2,6-bisphosphate 2-phosphatase activity Human EC:2.7.1.105 PFKFB4 UniProtKB UniProtKB {GO:0005975=Reactome:REACT_474, GO:0004331=GO_REF:0000003, GO:0006006=Reactome:REACT_723, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0006003=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0006096=Reactome:REACT_1383, GO:0003873=GO_REF:0000003, GO:0005829=Reactome:REACT_291, GO:0006000=GO_REF:0000002} Q66S35 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 4 isoform 1 protein 20130413 {GO:0005975=TAS, GO:0004331=IEA, GO:0006006=TAS, GO:0044281=TAS, GO:0003824=IEA, GO:0006003=IEA, GO:0005524=IEA, GO:0006096=TAS, GO:0003873=IEA, GO:0005829=TAS, GO:0006000=IEA} carbohydrate metabolic process, fructose 2,6-bisphosphate metabolic process, fructose metabolic process, glucose metabolic process, glycolysis, small molecule metabolic process cytosol 6-phosphofructo-2-kinase activity, ATP binding, catalytic activity, fructose-2,6-bisphosphate 2-phosphatase activity Human EC:3.1.3.46 PFKL BHF-UCL UniProtKB {GO:0005515=PMID:21988832, GO:0005975=Reactome:REACT_474, GO:0070095=PMID:6444721, GO:0044281=Reactome:REACT_111217, GO:0051259=PMID:6444721, GO:0005524=PMID:8780720, GO:0046872=GO_REF:0000037, GO:0006096=Reactome:REACT_1383, GO:0042802=PMID:6444721, GO:0005829=Reactome:REACT_736, GO:0009749=PMID:22923583, GO:0030388=PMID:22923583, GO:0051289=GO_REF:0000019, GO:0006006=Reactome:REACT_723, GO:0019900=PMID:6444721, GO:0046676=GO_REF:0000019, GO:0006002=PMID:6227635, GO:0070061=PMID:8780720, GO:0005945=PMID:6444721, GO:0003872=PMID:22923583} P17858 6-phosphofructokinase, liver type protein 20081008 {GO:0005515=IPI, GO:0005975=TAS, GO:0070095=IDA, GO:0044281=TAS, GO:0051259=IDA, GO:0005524=IDA, GO:0046872=IEA, GO:0006096=TAS, GO:0042802=IPI, GO:0005829=TAS, GO:0009749=IDA, GO:0030388=IDA, GO:0051289=IEA, GO:0006006=TAS, GO:0019900=IPI, GO:0046676=IEA, GO:0006002=IMP, GO:0070061=IDA, GO:0005945=IDA, GO:0003872=IDA} carbohydrate metabolic process, fructose 1,6-bisphosphate metabolic process, fructose 6-phosphate metabolic process, glucose metabolic process, glycolysis, negative regulation of insulin secretion, protein homotetramerization, protein oligomerization, response to glucose stimulus, small molecule metabolic process 6-phosphofructokinase complex, cytosol 6-phosphofructokinase activity, ATP binding, fructose binding, fructose-6-phosphate binding, identical protein binding, kinase binding, metal ion binding, protein binding Human PFKM BHF-UCL UniProtKB {GO:0005515=PMID:21988832, GO:0005975=Reactome:REACT_474, GO:0044281=Reactome:REACT_111217, GO:0042593=GO_REF:0000019, GO:0008022=PMID:12649290, GO:0005524=PMID:8780720, GO:0051259=PMID:6444721, GO:0046716=PMID:6444532, GO:0006096=Reactome:REACT_1383, GO:0046872=GO_REF:0000037, GO:0042802=PMID:6444721, GO:0005829=Reactome:REACT_736, GO:0016324=PMID:12649290, GO:0006006=Reactome:REACT_723, GO:0032024=GO_REF:0000019, GO:0019900=PMID:6444721, GO:0006002=PMID:6444532, GO:0070061=PMID:8780720, GO:0003872=PMID:8780720, GO:0005945=PMID:6444532} P08237 6-phosphofructokinase, muscle type protein 20081008 {GO:0005515=IPI, GO:0005975=TAS, GO:0044281=TAS, GO:0042593=IEA, GO:0008022=IPI, GO:0005524=IDA, GO:0051259=IDA, GO:0046716=IMP, GO:0006096=TAS, GO:0046872=IEA, GO:0042802=IPI, GO:0005829=TAS, GO:0016324=IDA, GO:0006006=TAS, GO:0032024=IEA, GO:0019900=IPI, GO:0006002=IMP, GO:0070061=IDA, GO:0003872=IDA, GO:0005945=IDA} carbohydrate metabolic process, fructose 6-phosphate metabolic process, glucose homeostasis, glucose metabolic process, glycolysis, muscle cell homeostasis, positive regulation of insulin secretion, protein oligomerization, small molecule metabolic process 6-phosphofructokinase complex, apical plasma membrane, cytosol 6-phosphofructokinase activity, ATP binding, fructose binding, identical protein binding, kinase binding, metal ion binding, protein C-terminus binding, protein binding Human PFKP InterPro UniProtKB {GO:0005975=Reactome:REACT_474, GO:0006006=Reactome:REACT_723, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0006002=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0006096=GO_REF:0000002, GO:0005829=Reactome:REACT_736, GO:0005945=GO_REF:0000002, GO:0003872=GO_REF:0000002} Q5VSR6 6-phosphofructokinase type C protein 20130413 {GO:0005975=TAS, GO:0006006=TAS, GO:0044281=TAS, GO:0005524=IEA, GO:0006002=IEA, GO:0046872=IEA, GO:0006096=IEA, GO:0005829=TAS, GO:0005945=IEA, GO:0003872=IEA} carbohydrate metabolic process, fructose 6-phosphate metabolic process, glucose metabolic process, glycolysis, small molecule metabolic process 6-phosphofructokinase complex, cytosol 6-phosphofructokinase activity, ATP binding, metal ion binding Human InterPro:IPR000023|InterPro:IPR022953 PFN1 IntAct UniProtKB {GO:0005515=PMID:9843499, GO:0008219=GO_REF:0000037, GO:0043005=GO_REF:0000019, GO:0051054=GO_REF:0000019, GO:0030036=GO_REF:0000002, GO:0005102=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0001843=GO_REF:0000019, GO:0005546=GO_REF:0000019, GO:0045202=GO_REF:0000019, GO:0003779=PMID:17914456, GO:0005634=GO_REF:0000019, GO:0050434=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0071363=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0045944=GO_REF:0000019, GO:0002576=Reactome:REACT_318, GO:0051496=GO_REF:0000019, GO:0017048=GO_REF:0000019, GO:0005856=GO_REF:0000039, GO:0070064=PMID:17914456} P07737 Profilin-1 protein 20130415 {GO:0005515=IPI, GO:0008219=IEA, GO:0043005=IEA, GO:0051054=IEA, GO:0030036=IEA, GO:0005102=IEA, GO:0030168=TAS, GO:0001843=IEA, GO:0005546=IEA, GO:0045202=IEA, GO:0003779=IPI, GO:0005634=IEA, GO:0050434=IEA, GO:0005737=IEA, GO:0071363=IEA, GO:0007596=TAS, GO:0045944=IEA, GO:0002576=TAS, GO:0051496=IEA, GO:0017048=IEA, GO:0005856=IEA, GO:0070064=IPI} actin cytoskeleton organization, blood coagulation, cell death, cellular response to growth factor stimulus, neural tube closure, platelet activation, platelet degranulation, positive regulation of DNA metabolic process, positive regulation of stress fiber assembly, positive regulation of transcription from RNA polymerase II promoter, positive regulation of viral transcription cytoplasm, cytoskeleton, neuron projection, nucleus, synapse Rho GTPase binding, actin binding, phosphatidylinositol-4,5-bisphosphate binding, proline-rich region binding, protein binding, receptor binding Human UniProtKB:Q92558 PFN2 IntAct UniProtKB {GO:0005515=PMID:16169070, GO:0005737=GO_REF:0000037, GO:0030036=GO_REF:0000002, GO:0030838=GO_REF:0000019, GO:0008064=GO_REF:0000029, GO:0043195=GO_REF:0000019, GO:2000300=GO_REF:0000019, GO:0030837=GO_REF:0000019, GO:0005546=GO_REF:0000029, GO:0003779=GO_REF:0000029, GO:0015629=GO_REF:0000029} P35080 Profilin-2 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0030036=IEA, GO:0030838=IEA, GO:0008064=NAS, GO:0043195=IEA, GO:2000300=IEA, GO:0030837=IEA, GO:0005546=NAS, GO:0003779=NAS, GO:0015629=NAS} actin cytoskeleton organization, negative regulation of actin filament polymerization, positive regulation of actin filament polymerization, regulation of actin polymerization or depolymerization, regulation of synaptic vesicle exocytosis actin cytoskeleton, cytoplasm, terminal bouton actin binding, phosphatidylinositol-4,5-bisphosphate binding, protein binding Human UniProtKB:Q14789 PFN4 UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0030036=GO_REF:0000002, GO:0003779=GO_REF:0000037, GO:0005856=GO_REF:0000039} Q8NHR9 Profilin-4 protein 20130413 {GO:0005737=IEA, GO:0030036=IEA, GO:0003779=IEA, GO:0005856=IEA} actin cytoskeleton organization cytoplasm, cytoskeleton actin binding Human UniProtKB-SubCell:SL-0090 PGAM1 Reactome UniProtKB {GO:0045730=PMID:12189148, GO:0004082=GO_REF:0000003, GO:0019901=PMID:12189148, GO:0004083=GO_REF:0000003, GO:0005975=Reactome:REACT_474, GO:0006094=Reactome:REACT_1520, GO:0044281=Reactome:REACT_111217, GO:0043456=PMID:12189148, GO:0006096=Reactome:REACT_1383, GO:0005829=Reactome:REACT_766, GO:0006110=PMID:12189148, GO:0006006=Reactome:REACT_723, GO:0004619=PMID:12189148} P18669 Phosphoglycerate mutase 1 protein 20070622 {GO:0045730=IDA, GO:0004082=IEA, GO:0019901=IPI, GO:0004083=IEA, GO:0005975=TAS, GO:0006094=TAS, GO:0044281=TAS, GO:0043456=IDA, GO:0006096=TAS, GO:0005829=TAS, GO:0006110=IDA, GO:0006006=TAS, GO:0004619=IMP} carbohydrate metabolic process, gluconeogenesis, glucose metabolic process, glycolysis, regulation of glycolysis, regulation of pentose-phosphate shunt, respiratory burst, small molecule metabolic process cytosol bisphosphoglycerate 2-phosphatase activity, bisphosphoglycerate mutase activity, phosphoglycerate mutase activity, protein kinase binding Human PGAM2 Reactome UniProtKB {GO:0048037=GO_REF:0000019, GO:0004082=GO_REF:0000003, GO:0004083=GO_REF:0000003, GO:0005975=Reactome:REACT_474, GO:0046538=GO_REF:0000019, GO:0006094=Reactome:REACT_1520, GO:0006941=PMID:6262916, GO:0005634=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0007283=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0006096=Reactome:REACT_1383, GO:0005829=Reactome:REACT_766, GO:0006006=Reactome:REACT_723, GO:0004619=PMID:6262916, GO:0046689=GO_REF:0000019} P15259 Phosphoglycerate mutase 2 protein 20070622 {GO:0048037=IEA, GO:0004082=IEA, GO:0004083=IEA, GO:0005975=TAS, GO:0046538=IEA, GO:0006094=TAS, GO:0006941=IMP, GO:0005634=IEA, GO:0044281=TAS, GO:0007283=IEA, GO:0005575=ND, GO:0006096=TAS, GO:0005829=TAS, GO:0006006=TAS, GO:0004619=IMP, GO:0046689=IEA} carbohydrate metabolic process, gluconeogenesis, glucose metabolic process, glycolysis, response to mercury ion, small molecule metabolic process, spermatogenesis, striated muscle contraction cellular_component, cytosol, nucleus 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity, bisphosphoglycerate 2-phosphatase activity, bisphosphoglycerate mutase activity, cofactor binding, phosphoglycerate mutase activity Human PGAM4 UniProtKB UniProtKB {GO:0004082=GO_REF:0000003, GO:0004083=GO_REF:0000003, GO:0005575=GO_REF:0000015, GO:0004619=PMID:11961099, GO:0006096=PMID:11961099} Q8N0Y7 Probable phosphoglycerate mutase 4 protein 20041109 {GO:0004082=IEA, GO:0004083=IEA, GO:0005575=ND, GO:0004619=NAS, GO:0006096=NAS} glycolysis cellular_component bisphosphoglycerate 2-phosphatase activity, bisphosphoglycerate mutase activity, phosphoglycerate mutase activity Human PGAM5 UniProtKB UniProtKB {GO:0005741=GO_REF:0000039, GO:0004721=GO_REF:0000003, GO:0016021=GO_REF:0000037} Q96HS1 Serine/threonine-protein phosphatase PGAM5, mitochondrial protein 20130413 {GO:0005741=IEA, GO:0004721=IEA, GO:0016021=IEA} integral to membrane, mitochondrial outer membrane phosphoprotein phosphatase activity Human UniProtKB-SubCell:SL-0172 PGAP1 Reactome UniProtKB {GO:0006501=Reactome:REACT_1853, GO:0005783=GO_REF:0000024, GO:0016255=Reactome:REACT_1830, GO:0007605=GO_REF:0000019, GO:0016788=GO_REF:0000002, GO:0006886=GO_REF:0000002, GO:0021871=GO_REF:0000019, GO:0015798=GO_REF:0000024, GO:0009880=GO_REF:0000019, GO:0042578=GO_REF:0000024, GO:0004518=GO_REF:0000024, GO:0009948=GO_REF:0000019, GO:0005789=Reactome:REACT_1978, GO:0060322=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0006505=GO_REF:0000002} Q75T13 GPI inositol-deacylase protein 20130301 {GO:0006501=TAS, GO:0005783=ISS, GO:0016255=TAS, GO:0007605=IEA, GO:0016788=IEA, GO:0006886=IEA, GO:0021871=IEA, GO:0015798=ISS, GO:0009880=IEA, GO:0042578=ISS, GO:0004518=ISS, GO:0009948=IEA, GO:0005789=TAS, GO:0060322=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0043687=TAS, GO:0006505=IEA} C-terminal protein lipidation, GPI anchor metabolic process, anterior/posterior axis specification, attachment of GPI anchor to protein, cellular protein metabolic process, embryonic pattern specification, forebrain regionalization, head development, intracellular protein transport, myo-inositol transport, post-translational protein modification, sensory perception of sound endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane hydrolase activity, acting on ester bonds, nuclease activity, phosphoric ester hydrolase activity Human PGBD3 null null {} null null null null {} null null null PGBD5 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8N414 PiggyBac transposable element-derived protein 5 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 PGC HPA UniProtKB {GO:0007586=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0006508=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0004190=GO_REF:0000002, GO:0005615=PMID:3335549} Q4VXA6 Gastricsin protein 20101115 {GO:0007586=IEA, GO:0005730=IDA, GO:0006508=IEA, GO:0005634=IDA, GO:0004190=IEA, GO:0005615=TAS} digestion, proteolysis extracellular space, nucleolus, nucleus aspartic-type endopeptidase activity NOT Human PGD Reactome UniProtKB {GO:0050661=GO_REF:0000002, GO:0004616=Reactome:REACT_611, GO:0019322=GO_REF:0000019, GO:0005975=Reactome:REACT_474, GO:0019521=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0006098=Reactome:REACT_1859, GO:0009051=PMID:3858849, GO:0005829=Reactome:REACT_611, GO:0055114=PMID:3858849} P52209 6-phosphogluconate dehydrogenase, decarboxylating protein 20130213 {GO:0050661=IEA, GO:0004616=EXP, GO:0019322=IEA, GO:0005975=TAS, GO:0019521=IEA, GO:0044281=TAS, GO:0006098=TAS, GO:0009051=IDA, GO:0005829=TAS, GO:0055114=IDA} D-gluconate metabolic process, carbohydrate metabolic process, oxidation-reduction process, pentose biosynthetic process, pentose-phosphate shunt, pentose-phosphate shunt, oxidative branch, small molecule metabolic process cytosol NADP binding, phosphogluconate dehydrogenase (decarboxylating) activity Human PGF Reactome UniProtKB {GO:0048010=Reactome:REACT_12529, GO:0001666=GO_REF:0000019, GO:0008284=PMID:21215706, GO:0001658=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0031100=GO_REF:0000019, GO:0007267=PMID:9467961, GO:0005576=Reactome:REACT_12588, GO:0002040=GO_REF:0000019, GO:0060688=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0045766=GO_REF:0000019, GO:0032870=GO_REF:0000019, GO:0030154=GO_REF:0000037, GO:0007165=PMID:9467961, GO:0016020=GO_REF:0000002, GO:0001938=GO_REF:0000019, GO:0051781=GO_REF:0000037, GO:0008083=PMID:21215706, GO:0008201=GO_REF:0000037} P49763 Placenta growth factor protein 20130204 {GO:0048010=TAS, GO:0001666=IEA, GO:0008284=IMP, GO:0001658=IEA, GO:0007565=IEA, GO:0046982=IEA, GO:0042493=IEA, GO:0031100=IEA, GO:0007267=TAS, GO:0005576=TAS, GO:0002040=IEA, GO:0060688=IEA, GO:0005615=IEA, GO:0042803=IEA, GO:0045766=IEA, GO:0032870=IEA, GO:0030154=IEA, GO:0007165=TAS, GO:0016020=IEA, GO:0001938=IEA, GO:0051781=IEA, GO:0008083=IMP, GO:0008201=IEA} branching involved in ureteric bud morphogenesis, cell differentiation, cell-cell signaling, cellular response to hormone stimulus, female pregnancy, organ regeneration, positive regulation of angiogenesis, positive regulation of cell division, positive regulation of cell proliferation, positive regulation of endothelial cell proliferation, regulation of morphogenesis of a branching structure, response to drug, response to hypoxia, signal transduction, sprouting angiogenesis, vascular endothelial growth factor receptor signaling pathway extracellular region, extracellular space, membrane growth factor activity, heparin binding, protein heterodimerization activity, protein homodimerization activity Human PGGT1B PINC UniProtKB {GO:0008284=GO_REF:0000019, GO:0018344=PMID:8106351, GO:0004662=GO_REF:0000003, GO:0034097=GO_REF:0000019, GO:0051771=GO_REF:0000019, GO:0045787=GO_REF:0000019, GO:0005953=GO_REF:0000019, GO:0046872=GO_REF:0000037} P53609 Geranylgeranyl transferase type-1 subunit beta protein 20031119 {GO:0008284=IEA, GO:0018344=TAS, GO:0004662=IEA, GO:0034097=IEA, GO:0051771=IEA, GO:0045787=IEA, GO:0005953=IEA, GO:0046872=IEA} negative regulation of nitric-oxide synthase biosynthetic process, positive regulation of cell cycle, positive regulation of cell proliferation, protein geranylgeranylation, response to cytokine stimulus CAAX-protein geranylgeranyltransferase complex CAAX-protein geranylgeranyltransferase activity, metal ion binding Human PGK1 Reactome UniProtKB {GO:0016310=GO_REF:0000024, GO:0004618=Reactome:REACT_1186, GO:0005975=Reactome:REACT_474, GO:0006094=Reactome:REACT_1520, GO:0006006=Reactome:REACT_723, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000024, GO:0006096=Reactome:REACT_1383, GO:0005829=Reactome:REACT_1186} P00558 Phosphoglycerate kinase 1 protein 20130213 {GO:0016310=ISS, GO:0004618=EXP, GO:0005975=TAS, GO:0006094=TAS, GO:0006006=TAS, GO:0044281=TAS, GO:0005524=ISS, GO:0006096=TAS, GO:0005829=TAS} carbohydrate metabolic process, gluconeogenesis, glucose metabolic process, glycolysis, phosphorylation, small molecule metabolic process cytosol ATP binding, phosphoglycerate kinase activity Human PGK2 UniProtKB UniProtKB {GO:0016310=GO_REF:0000024, GO:0004618=GO_REF:0000024, GO:0005524=GO_REF:0000024, GO:0006096=PMID:3453121, GO:0005829=GO_REF:0000029} P07205 Phosphoglycerate kinase 2 protein 20021104 {GO:0016310=ISS, GO:0004618=ISS, GO:0005524=ISS, GO:0006096=NAS, GO:0005829=NAS} glycolysis, phosphorylation cytosol ATP binding, phosphoglycerate kinase activity Human PGLS Reactome UniProtKB {GO:0005975=Reactome:REACT_474, GO:0017057=PMID:10518023, GO:0044281=Reactome:REACT_111217, GO:0048029=GO_REF:0000019, GO:0006098=Reactome:REACT_1859, GO:0009051=GO_REF:0000019, GO:0005829=Reactome:REACT_2072} O95336 6-phosphogluconolactonase protein 20130301 {GO:0005975=TAS, GO:0017057=IDA, GO:0044281=TAS, GO:0048029=IEA, GO:0006098=TAS, GO:0009051=IEA, GO:0005829=TAS} carbohydrate metabolic process, pentose-phosphate shunt, pentose-phosphate shunt, oxidative branch, small molecule metabolic process cytosol 6-phosphogluconolactonase activity, monosaccharide binding Human PGLYRP1 PINC UniProtKB {GO:0016019=PMID:11461926, GO:0050830=PMID:11461926, GO:0044117=GO_REF:0000019, GO:0042834=PMID:17502600, GO:0008745=GO_REF:0000002, GO:0005576=PMID:11461926, GO:0032827=GO_REF:0000019, GO:0009253=GO_REF:0000002, GO:0051635=PMID:9707603, GO:0006955=PMID:9707603, GO:0045087=PMID:11461926, GO:0008270=GO_REF:0000002, GO:0032689=GO_REF:0000019, GO:0016045=PMID:11461926} O75594 Peptidoglycan recognition protein 1 protein 20030904 {GO:0016019=IDA, GO:0050830=IDA, GO:0044117=IEA, GO:0042834=IDA, GO:0008745=IEA, GO:0005576=NAS, GO:0032827=IEA, GO:0009253=IEA, GO:0051635=TAS, GO:0006955=TAS, GO:0045087=NAS, GO:0008270=IEA, GO:0032689=IEA, GO:0016045=IDA} defense response to Gram-positive bacterium, detection of bacterium, growth of symbiont in host, immune response, innate immune response, negative regulation of interferon-gamma production, negative regulation of natural killer cell differentiation involved in immune response, peptidoglycan catabolic process extracellular region N-acetylmuramoyl-L-alanine amidase activity, bacterial cell surface binding, peptidoglycan binding, peptidoglycan receptor activity, zinc ion binding Human PGLYRP3 UniProtKB UniProtKB {GO:0016019=PMID:11461926, GO:0050830=PMID:11461926, GO:0044117=GO_REF:0000019, GO:0042834=PMID:17502600, GO:0008745=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0032827=GO_REF:0000019, GO:0009253=GO_REF:0000002, GO:0005622=PMID:11461926, GO:0016020=PMID:11461926, GO:0045087=PMID:11461926, GO:0008270=GO_REF:0000002, GO:0032689=GO_REF:0000019, GO:0016045=PMID:11461926} Q96LB9 Peptidoglycan recognition protein 3 protein 20090721 {GO:0016019=IDA, GO:0050830=IDA, GO:0044117=IEA, GO:0042834=IDA, GO:0008745=IEA, GO:0005576=IEA, GO:0032827=IEA, GO:0009253=IEA, GO:0005622=NAS, GO:0016020=NAS, GO:0045087=NAS, GO:0008270=IEA, GO:0032689=IEA, GO:0016045=IDA} defense response to Gram-positive bacterium, detection of bacterium, growth of symbiont in host, innate immune response, negative regulation of interferon-gamma production, negative regulation of natural killer cell differentiation involved in immune response, peptidoglycan catabolic process extracellular region, intracellular, membrane N-acetylmuramoyl-L-alanine amidase activity, peptidoglycan binding, peptidoglycan receptor activity, zinc ion binding Human PGM1 HPA UniProtKB {GO:0000287=GO_REF:0000002, GO:0005975=Reactome:REACT_474, GO:0005978=Reactome:REACT_1736, GO:0006094=PMID:8257433, GO:0019388=Reactome:REACT_532, GO:0044281=Reactome:REACT_111217, GO:0015629=GO_REF:0000052, GO:0006096=PMID:8257433, GO:0005829=Reactome:REACT_2164, GO:0005737=GO_REF:0000029, GO:0004614=PMID:8257433, GO:0006006=Reactome:REACT_723, GO:0005992=GO_REF:0000033, GO:0005980=Reactome:REACT_1008} P36871 Phosphoglucomutase-1 protein 20111111 {GO:0000287=IEA, GO:0005975=TAS, GO:0005978=TAS, GO:0006094=TAS, GO:0019388=TAS, GO:0044281=TAS, GO:0015629=IDA, GO:0006096=TAS, GO:0005829=TAS, GO:0005737=NAS, GO:0004614=TAS, GO:0006006=TAS, GO:0005992=IBA, GO:0005980=TAS} carbohydrate metabolic process, galactose catabolic process, gluconeogenesis, glucose metabolic process, glycogen biosynthetic process, glycogen catabolic process, glycolysis, small molecule metabolic process, trehalose biosynthetic process actin cytoskeleton, cytoplasm, cytosol magnesium ion binding, phosphoglucomutase activity Human PGM2 Reactome UniProtKB {GO:0000287=GO_REF:0000002, GO:0005975=Reactome:REACT_474, GO:0005978=Reactome:REACT_1736, GO:0019388=Reactome:REACT_532, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_2164, GO:0016052=GO_REF:0000033, GO:0004614=GO_REF:0000033, GO:0006006=Reactome:REACT_723, GO:0046386=GO_REF:0000041, GO:0016868=GO_REF:0000002, GO:0008973=PMID:17804405, GO:0005980=Reactome:REACT_1008} Q96G03 Phosphoglucomutase-2 protein 20130213 {GO:0000287=IEA, GO:0005975=TAS, GO:0005978=TAS, GO:0019388=TAS, GO:0044281=TAS, GO:0005829=TAS, GO:0016052=IBA, GO:0004614=IBA, GO:0006006=TAS, GO:0046386=IEA, GO:0016868=IEA, GO:0008973=IDA, GO:0005980=TAS} carbohydrate catabolic process, carbohydrate metabolic process, deoxyribose phosphate catabolic process, galactose catabolic process, glucose metabolic process, glycogen biosynthetic process, glycogen catabolic process, small molecule metabolic process cytosol intramolecular transferase activity, phosphotransferases, magnesium ion binding, phosphoglucomutase activity, phosphopentomutase activity Human PGM2L1 UniProtKB UniProtKB {GO:0047933=PMID:17804405, GO:0016052=GO_REF:0000033, GO:0005975=GO_REF:0000002, GO:0004614=GO_REF:0000033, GO:0006006=GO_REF:0000037, GO:0016868=GO_REF:0000002, GO:0005829=GO_REF:0000033} Q6PCE3 Glucose 1,6-bisphosphate synthase protein 20120612 {GO:0047933=IDA, GO:0016052=IBA, GO:0005975=IEA, GO:0004614=IBA, GO:0006006=IEA, GO:0016868=IEA, GO:0005829=IBA} carbohydrate catabolic process, carbohydrate metabolic process, glucose metabolic process cytosol glucose-1,6-bisphosphate synthase activity, intramolecular transferase activity, phosphotransferases, phosphoglucomutase activity Human PGM3 Reactome UniProtKB {GO:0030097=GO_REF:0000033, GO:0000287=GO_REF:0000002, GO:0019255=GO_REF:0000019, GO:0005975=GO_REF:0000002, GO:0006041=PMID:11004509, GO:0007283=GO_REF:0000019, GO:0009790=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0004610=PMID:11004509, GO:0006048=Reactome:REACT_22394, GO:0005829=Reactome:REACT_22269, GO:0004614=GO_REF:0000019, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} O95394 Phosphoacetylglucosamine mutase protein 20130301 {GO:0030097=IBA, GO:0000287=IEA, GO:0019255=IEA, GO:0005975=IEA, GO:0006041=NAS, GO:0007283=IEA, GO:0009790=IEA, GO:0005575=ND, GO:0004610=IDA, GO:0006048=TAS, GO:0005829=TAS, GO:0004614=IEA, GO:0006488=TAS, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS} UDP-N-acetylglucosamine biosynthetic process, carbohydrate metabolic process, cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, embryo development, glucosamine metabolic process, glucose 1-phosphate metabolic process, hemopoiesis, post-translational protein modification, protein N-linked glycosylation via asparagine, spermatogenesis cellular_component, cytosol magnesium ion binding, phosphoacetylglucosamine mutase activity, phosphoglucomutase activity Human PGM5 InterPro UniProtKB {GO:0030018=GO_REF:0000033, GO:0001725=PMID:8175905, GO:0000287=GO_REF:0000002, GO:0005975=GO_REF:0000002, GO:0005978=GO_REF:0000033, GO:0019388=GO_REF:0000033, GO:0005829=GO_REF:0000033, GO:0042383=PMID:10867799, GO:0005914=PMID:8175905, GO:0005913=PMID:8175905, GO:0014704=PMID:8175905, GO:0016010=GO_REF:0000024, GO:0005198=PMID:8631316, GO:0004614=PMID:8175905, GO:0043034=PMID:8175905, GO:0005992=GO_REF:0000033, GO:0009898=PMID:10867799, GO:0006006=GO_REF:0000037, GO:0016868=GO_REF:0000002, GO:0007155=GO_REF:0000037, GO:0005925=PMID:8175905} Q5JTY7 Phosphoglucomutase-like protein 5 protein 20130413 {GO:0030018=IBA, GO:0001725=IDA, GO:0000287=IEA, GO:0005975=IEA, GO:0005978=IBA, GO:0019388=IBA, GO:0005829=IBA, GO:0042383=IDA, GO:0005914=IDA, GO:0005913=IDA, GO:0014704=IDA, GO:0016010=ISS, GO:0005198=NAS, GO:0004614=IDA, GO:0043034=IDA, GO:0005992=IBA, GO:0009898=IDA, GO:0006006=IEA, GO:0016868=IEA, GO:0007155=IEA, GO:0005925=IDA} carbohydrate metabolic process, cell adhesion, galactose catabolic process, glucose metabolic process, glycogen biosynthetic process, trehalose biosynthetic process Z disc, cell-cell adherens junction, costamere, cytosol, dystrophin-associated glycoprotein complex, focal adhesion, intercalated disc, internal side of plasma membrane, sarcolemma, spot adherens junction, stress fiber intramolecular transferase activity, phosphotransferases, magnesium ion binding, phosphoglucomutase activity, structural molecule activity Human InterPro:IPR005841|InterPro:IPR005844|InterPro:IPR005845|InterPro:IPR016055 PGP UniProtKB UniProtKB {GO:0008967=GO_REF:0000003, GO:0005975=GO_REF:0000037} A6NDG6 Phosphoglycolate phosphatase protein 20130413 {GO:0008967=IEA, GO:0005975=IEA} carbohydrate metabolic process phosphoglycolate phosphatase activity Human EC:3.1.3.18 PGR HPA UniProtKB {GO:0005515=PMID:12011095, GO:0060748=GO_REF:0000019, GO:0010467=Reactome:REACT_71, GO:0050678=GO_REF:0000019, GO:0050847=GO_REF:0000019, GO:0006367=Reactome:REACT_15525, GO:0007267=PMID:1557371, GO:0003707=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0001542=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0003677=PMID:3551956, GO:0043231=GO_REF:0000052, GO:0043565=GO_REF:0000002, GO:0007165=PMID:1557371, GO:0005737=GO_REF:0000039, GO:0005654=Reactome:REACT_115653, GO:0008270=GO_REF:0000002, GO:0002070=GO_REF:0000019, GO:0004879=GO_REF:0000019, GO:0019899=PMID:12039952, GO:0005496=GO_REF:0000037} P06401 Progesterone receptor protein 20101115 {GO:0005515=IPI, GO:0060748=IEA, GO:0010467=TAS, GO:0050678=IEA, GO:0050847=IEA, GO:0006367=TAS, GO:0007267=TAS, GO:0003707=IEA, GO:0005730=IDA, GO:0001542=IEA, GO:0005634=IDA, GO:0003677=TAS, GO:0043231=IDA, GO:0043565=IEA, GO:0007165=TAS, GO:0005737=IEA, GO:0005654=TAS, GO:0008270=IEA, GO:0002070=IEA, GO:0004879=IEA, GO:0019899=IPI, GO:0005496=IEA} cell-cell signaling, epithelial cell maturation, gene expression, ovulation from ovarian follicle, progesterone receptor signaling pathway, regulation of epithelial cell proliferation, signal transduction, tertiary branching involved in mammary gland duct morphogenesis, transcription initiation from RNA polymerase II promoter cytoplasm, intracellular membrane-bounded organelle, nucleolus, nucleoplasm, nucleus DNA binding, enzyme binding, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, protein binding, sequence-specific DNA binding, steroid binding, steroid hormone receptor activity, zinc ion binding Human PGRMC1 HPA UniProtKB {GO:0009986=PMID:12493773, GO:0007411=GO_REF:0000019, GO:0005783=GO_REF:0000052, GO:0005789=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0016021=GO_REF:0000037, GO:0005496=GO_REF:0000037, GO:0020037=GO_REF:0000002} O00264 Membrane-associated progesterone receptor component 1 protein 20101115 {GO:0009986=IDA, GO:0007411=IEA, GO:0005783=IDA, GO:0005789=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0016021=IEA, GO:0005496=IEA, GO:0020037=IEA} axon guidance cell surface, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, nucleolus, nucleus heme binding, steroid binding Human PGRMC2 GOC UniProtKB {GO:0043401=PMID:9705155, GO:0003707=PMID:9705155, GO:0016021=GO_REF:0000037, GO:0005496=GO_REF:0000037, GO:0020037=GO_REF:0000002} O15173 Membrane-associated progesterone receptor component 2 protein 20130413 {GO:0043401=TAS, GO:0003707=TAS, GO:0016021=IEA, GO:0005496=IEA, GO:0020037=IEA} steroid hormone mediated signaling pathway integral to membrane heme binding, steroid binding, steroid hormone receptor activity Human PGS1 BHF-UCL UniProtKB {GO:0005783=GO_REF:0000054, GO:0005509=GO_REF:0000024, GO:0005743=PMID:11171073, GO:0008654=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0008444=GO_REF:0000024, GO:0005739=GO_REF:0000024, GO:0016780=GO_REF:0000002, GO:0032049=GO_REF:0000024, GO:0006644=Reactome:REACT_120870, GO:0006655=GO_REF:0000024, GO:0046474=Reactome:REACT_121401, GO:0046339=GO_REF:0000024} Q32NB8 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial protein 20111202 {GO:0005783=IDA, GO:0005509=ISS, GO:0005743=TAS, GO:0008654=IEA, GO:0044281=TAS, GO:0005524=IEA, GO:0008444=ISS, GO:0005739=ISS, GO:0016780=IEA, GO:0032049=ISS, GO:0006644=TAS, GO:0006655=ISS, GO:0046474=TAS, GO:0046339=ISS} cardiolipin biosynthetic process, diacylglycerol metabolic process, glycerophospholipid biosynthetic process, phosphatidylglycerol biosynthetic process, phospholipid biosynthetic process, phospholipid metabolic process, small molecule metabolic process endoplasmic reticulum, mitochondrial inner membrane, mitochondrion ATP binding, CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity, calcium ion binding, phosphotransferase activity, for other substituted phosphate groups Human UniProtKB:Q9Z2Z7 PHACTR1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0030054=GO_REF:0000037, GO:0031532=GO_REF:0000024, GO:0048870=PMID:22976292, GO:0004864=GO_REF:0000037, GO:0043149=PMID:22976292, GO:0031032=PMID:22976292, GO:0045202=GO_REF:0000039, GO:0005634=GO_REF:0000024, GO:0003779=GO_REF:0000024, GO:0005829=GO_REF:0000024} Q9C0D0 Phosphatase and actin regulator 1 protein 20101115 {GO:0005737=IDA, GO:0030054=IEA, GO:0031532=ISS, GO:0048870=IMP, GO:0004864=IEA, GO:0043149=IMP, GO:0031032=IMP, GO:0045202=IEA, GO:0005634=ISS, GO:0003779=ISS, GO:0005829=ISS} actin cytoskeleton reorganization, actomyosin structure organization, cell motility, stress fiber assembly cell junction, cytoplasm, cytosol, nucleus, synapse actin binding, protein phosphatase inhibitor activity Human PHACTR2 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0004864=GO_REF:0000037, GO:0003779=GO_REF:0000037} O75167 Phosphatase and actin regulator 2 protein 20130415 {GO:0005515=IPI, GO:0004864=IEA, GO:0003779=IEA} actin binding, protein binding, protein phosphatase inhibitor activity Human UniProtKB:P16333 PHACTR3 UniProtKB UniProtKB {GO:0004864=GO_REF:0000037, GO:0003779=GO_REF:0000037, GO:0016363=GO_REF:0000039} Q96KR7 Phosphatase and actin regulator 3 protein 20130413 {GO:0004864=IEA, GO:0003779=IEA, GO:0016363=IEA} nuclear matrix actin binding, protein phosphatase inhibitor activity Human UniProtKB-SubCell:SL-0181 PHACTR4 UniProtKB UniProtKB {GO:2001045=GO_REF:0000024, GO:0030036=GO_REF:0000024, GO:0001755=GO_REF:0000024, GO:0001843=GO_REF:0000024, GO:0003779=GO_REF:0000024, GO:0007266=GO_REF:0000024, GO:0043085=GO_REF:0000024, GO:0030027=GO_REF:0000024, GO:0048484=GO_REF:0000024, GO:0061386=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0051726=GO_REF:0000024, GO:0071862=GO_REF:0000024, GO:0008157=GO_REF:0000024} Q8IZ21 Phosphatase and actin regulator 4 protein 20120228 {GO:2001045=ISS, GO:0030036=ISS, GO:0001755=ISS, GO:0001843=ISS, GO:0003779=ISS, GO:0007266=ISS, GO:0043085=ISS, GO:0030027=ISS, GO:0048484=ISS, GO:0061386=ISS, GO:0005737=IEA, GO:0051726=ISS, GO:0071862=ISS, GO:0008157=ISS} Rho protein signal transduction, actin cytoskeleton organization, closure of optic fissure, enteric nervous system development, negative regulation of integrin-mediated signaling pathway, neural crest cell migration, neural tube closure, positive regulation of catalytic activity, regulation of cell cycle cytoplasm, lamellipodium actin binding, protein phosphatase 1 binding, protein phosphatase type 1 activator activity Human UniProtKB:Q501J7 PHAX BHF-UCL UniProtKB {GO:0010467=Reactome:REACT_71, GO:0015030=GO_REF:0000039, GO:0016070=Reactome:REACT_21257, GO:0006408=PMID:16687569, GO:0003723=GO_REF:0000037, GO:0015643=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0005654=Reactome:REACT_10069, GO:0034660=Reactome:REACT_11052, GO:0000387=Reactome:REACT_11066, GO:0015031=GO_REF:0000037, GO:0005829=Reactome:REACT_10069} Q9H814 Phosphorylated adapter RNA export protein protein 20091118 {GO:0010467=TAS, GO:0015030=IEA, GO:0016070=TAS, GO:0006408=TAS, GO:0003723=IEA, GO:0015643=IEA, GO:0043025=IEA, GO:0005654=TAS, GO:0034660=TAS, GO:0000387=TAS, GO:0015031=IEA, GO:0005829=TAS} RNA metabolic process, gene expression, ncRNA metabolic process, protein transport, snRNA export from nucleus, spliceosomal snRNP assembly Cajal body, cytosol, neuronal cell body, nucleoplasm RNA binding, toxic substance binding Human PHB BHF-UCL UniProtKB {GO:0005515=PMID:12065415, GO:0030308=PMID:12065415, GO:0008285=PMID:18487222, GO:0044212=PMID:18487222, GO:0042826=PMID:16964284, GO:0000981=GO_REF:0000019, GO:0005743=PMID:14500729, GO:0005634=PMID:16964284, GO:0005739=GO_REF:0000054, GO:0005737=PMID:16964284, GO:0010944=PMID:18487222, GO:0071354=PMID:17324931, GO:0050847=PMID:16964284, GO:0006355=PMID:14500729, GO:0016575=PMID:12466959, GO:0060766=PMID:16964284, GO:0042981=PMID:16130169, GO:0000122=PMID:16964284, GO:2000323=PMID:16964284, GO:0006260=GO_REF:0000037, GO:0007165=PMID:16130169, GO:0071897=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0005887=PMID:15274632, GO:0005654=PMID:12466959, GO:0045893=PMID:14500729, GO:0045892=PMID:12065415} P35232 Prohibitin protein 20110504 {GO:0005515=IPI, GO:0030308=IMP, GO:0008285=IMP, GO:0044212=IDA, GO:0042826=IPI, GO:0000981=IEA, GO:0005743=TAS, GO:0005634=IDA, GO:0005739=IDA, GO:0005737=IDA, GO:0010944=IDA, GO:0071354=IDA, GO:0050847=IDA, GO:0006355=IDA, GO:0016575=IDA, GO:0060766=IDA, GO:0042981=TAS, GO:0000122=IDA, GO:2000323=IDA, GO:0006260=IEA, GO:0007165=TAS, GO:0071897=IEA, GO:0016020=IEA, GO:0005887=IDA, GO:0005654=IDA, GO:0045893=IDA, GO:0045892=IDA} DNA biosynthetic process, DNA replication, cellular response to interleukin-6, histone deacetylation, negative regulation of androgen receptor signaling pathway, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of glucocorticoid receptor signaling pathway, negative regulation of transcription by competitive promoter binding, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of transcription, DNA-dependent, progesterone receptor signaling pathway, regulation of apoptotic process, regulation of transcription, DNA-dependent, signal transduction cytoplasm, integral to plasma membrane, membrane, mitochondrial inner membrane, mitochondrion, nucleoplasm, nucleus histone deacetylase binding, protein binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, transcription regulatory region DNA binding Human PHB2 HPA UniProtKB {GO:0005515=PMID:10359819, GO:0060744=GO_REF:0000019, GO:0060762=GO_REF:0000019, GO:0030331=PMID:10359819, GO:0005743=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0005739=GO_REF:0000052, GO:0016020=GO_REF:0000002, GO:0033147=GO_REF:0000019, GO:0033600=GO_REF:0000019, GO:0045892=PMID:10359819, GO:0060749=GO_REF:0000019} Q99623 Prohibitin-2 protein 20120912 {GO:0005515=IPI, GO:0060744=IEA, GO:0060762=IEA, GO:0030331=NAS, GO:0005743=ISS, GO:0005634=ISS, GO:0006351=IEA, GO:0005739=IDA, GO:0016020=IEA, GO:0033147=IEA, GO:0033600=IEA, GO:0045892=IDA, GO:0060749=IEA} mammary gland alveolus development, mammary gland branching involved in thelarche, negative regulation of intracellular estrogen receptor signaling pathway, negative regulation of mammary gland epithelial cell proliferation, negative regulation of transcription, DNA-dependent, regulation of branching involved in mammary gland duct morphogenesis, transcription, DNA-dependent membrane, mitochondrial inner membrane, mitochondrion, nucleus estrogen receptor binding, protein binding Human PHC1 HPA UniProtKB {GO:0031519=PMID:21282530, GO:0035102=PMID:19636380, GO:0016604=GO_REF:0000019, GO:0071300=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0007275=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0001739=GO_REF:0000019} P78364 Polyhomeotic-like protein 1 protein 20080818 {GO:0031519=IDA, GO:0035102=IDA, GO:0016604=IEA, GO:0071300=IEA, GO:0003682=IEA, GO:0005730=IDA, GO:0007275=IEA, GO:0008270=IEA, GO:0005634=IDA, GO:0003677=IEA, GO:0001739=IEA} cellular response to retinoic acid, multicellular organismal development PRC1 complex, PcG protein complex, nuclear body, nucleolus, nucleus, sex chromatin DNA binding, chromatin binding, zinc ion binding NOT Human PHC2 HPA UniProtKB {GO:0005515=PMID:21988832, GO:0031519=PMID:21282530, GO:0035102=PMID:19636380, GO:0005730=GO_REF:0000052, GO:0007275=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0007283=GO_REF:0000019, GO:0003677=GO_REF:0000037} Q8IXK0 Polyhomeotic-like protein 2 protein 20120912 {GO:0005515=IPI, GO:0031519=IDA, GO:0035102=IDA, GO:0005730=IDA, GO:0007275=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0007283=IEA, GO:0003677=IEA} multicellular organismal development, spermatogenesis PRC1 complex, PcG protein complex, nucleolus, nucleus DNA binding, protein binding, zinc ion binding NOT Human PHC3 HPA UniProtKB {GO:0031519=PMID:21282530, GO:0035102=PMID:19636380, GO:0007275=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0015629=GO_REF:0000052, GO:0003677=GO_REF:0000037} Q8NDX5 Polyhomeotic-like protein 3 protein 20111111 {GO:0031519=IDA, GO:0035102=IDA, GO:0007275=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0015629=IDA, GO:0003677=IEA} multicellular organismal development PRC1 complex, PcG protein complex, actin cytoskeleton, nucleus DNA binding, zinc ion binding Human PHEX PINC UniProtKB {GO:0048471=GO_REF:0000019, GO:0005794=GO_REF:0000019, GO:0005886=PMID:9593714, GO:0005783=GO_REF:0000019, GO:0007267=PMID:7550339, GO:0030282=GO_REF:0000019, GO:0001501=PMID:9070861, GO:0005887=PMID:9593714, GO:0004177=GO_REF:0000037, GO:0006508=PMID:11409890, GO:0008270=PMID:9070861, GO:0019637=GO_REF:0000019, GO:0004222=GO_REF:0000002, GO:0006464=PMID:7550339} P78562 Phosphate-regulating neutral endopeptidase protein 20030904 {GO:0048471=IEA, GO:0005794=IEA, GO:0005886=TAS, GO:0005783=IEA, GO:0007267=TAS, GO:0030282=IEA, GO:0001501=TAS, GO:0005887=TAS, GO:0004177=IEA, GO:0006508=IDA, GO:0008270=TAS, GO:0019637=IEA, GO:0004222=IEA, GO:0006464=TAS} bone mineralization, cell-cell signaling, cellular protein modification process, organophosphate metabolic process, proteolysis, skeletal system development Golgi apparatus, endoplasmic reticulum, integral to plasma membrane, perinuclear region of cytoplasm, plasma membrane aminopeptidase activity, metalloendopeptidase activity, zinc ion binding Human PHF1 PINC UniProtKB {GO:0003700=PMID:9545646, GO:0005815=GO_REF:0000039, GO:0061087=PMID:23273982, GO:0061086=PMID:23142980, GO:0035861=PMID:23142980, GO:0005634=PMID:23273982, GO:0035064=PMID:23273982, GO:0006351=GO_REF:0000037, GO:0006974=PMID:23142980, GO:0005737=GO_REF:0000037, GO:0035098=PMID:23273982, GO:0008270=GO_REF:0000002, GO:0016568=GO_REF:0000037} O43189 PHD finger protein 1 protein 20030904 {GO:0003700=TAS, GO:0005815=IEA, GO:0061087=IMP, GO:0061086=IMP, GO:0035861=IDA, GO:0005634=IDA, GO:0035064=IDA, GO:0006351=IEA, GO:0006974=IDA, GO:0005737=IEA, GO:0035098=IDA, GO:0008270=IEA, GO:0016568=IEA} chromatin modification, negative regulation of histone H3-K27 methylation, positive regulation of histone H3-K27 methylation, response to DNA damage stimulus, transcription, DNA-dependent ESC/E(Z) complex, cytoplasm, microtubule organizing center, nucleus, site of double-strand break methylated histone residue binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human PHF10 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0071564=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0007399=GO_REF:0000037} Q8WUB8 PHD finger protein 10 protein 20100126 {GO:0006355=IEA, GO:0008270=IEA, GO:0071564=ISS, GO:0006351=IEA, GO:0007399=IEA} nervous system development, regulation of transcription, DNA-dependent, transcription, DNA-dependent npBAF complex zinc ion binding Human UniProtKB:Q9D8M7 PHF11 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q9UIL8 PHD finger protein 11 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus zinc ion binding Human UniProtKB-SubCell:SL-0191 PHF12 HPA UniProtKB {GO:0005515=PMID:11390640, GO:0001222=GO_REF:0000019, GO:0016580=PMID:22048773, GO:0001106=PMID:22048773, GO:0017053=PMID:11390640, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0000122=PMID:22048773, GO:0035091=PMID:16893883, GO:0045892=PMID:11390640} Q96QT6 PHD finger protein 12 protein 20090616 {GO:0005515=IPI, GO:0001222=IEA, GO:0016580=IDA, GO:0001106=IDA, GO:0017053=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0000122=IDA, GO:0035091=IDA, GO:0045892=IDA} negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent Sin3 complex, nucleolus, nucleus, transcriptional repressor complex RNA polymerase II transcription corepressor activity, phosphatidylinositol binding, protein binding, transcription corepressor binding, zinc ion binding NOT Human PHF13 UniProtKB UniProtKB {GO:0007076=PMID:19638409, GO:0007059=PMID:19638409, GO:0003682=PMID:19638409, GO:0005634=PMID:19638409, GO:0005654=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0035064=PMID:19638409, GO:0000278=PMID:19638409, GO:0051301=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q86YI8 PHD finger protein 13 protein 20110216 {GO:0007076=IMP, GO:0007059=IMP, GO:0003682=IDA, GO:0005634=IDA, GO:0005654=IEA, GO:0008270=IEA, GO:0035064=NAS, GO:0000278=IMP, GO:0051301=IEA, GO:0016568=IEA} cell division, chromatin modification, chromosome segregation, mitotic cell cycle, mitotic chromosome condensation nucleoplasm, nucleus chromatin binding, methylated histone residue binding, zinc ion binding Human PHF14 InterPro UniProtKB {GO:0008270=GO_REF:0000002} O94880 PHD finger protein 14 protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR001965 PHF15 UniProtKB UniProtKB {GO:0043981=PMID:16387653, GO:0043983=PMID:16387653, GO:0043982=PMID:16387653, GO:0043966=PMID:16387653, GO:0043984=PMID:16387653, GO:0000123=PMID:16387653, GO:0008270=GO_REF:0000002} Q9NQC1 Protein Jade-2 protein 20090529 {GO:0043981=IDA, GO:0043983=IDA, GO:0043982=IDA, GO:0043966=IDA, GO:0043984=IDA, GO:0000123=IDA, GO:0008270=IEA} histone H3 acetylation, histone H4-K12 acetylation, histone H4-K16 acetylation, histone H4-K5 acetylation, histone H4-K8 acetylation histone acetyltransferase complex zinc ion binding Human PHF16 UniProtKB UniProtKB {GO:0043981=PMID:16387653, GO:0043983=PMID:16387653, GO:0043982=PMID:16387653, GO:0043966=PMID:16387653, GO:0043984=PMID:16387653, GO:0000123=PMID:16387653, GO:0008270=GO_REF:0000002} Q92613 Protein Jade-3 protein 20090529 {GO:0043981=IDA, GO:0043983=IDA, GO:0043982=IDA, GO:0043966=IDA, GO:0043984=IDA, GO:0000123=IDA, GO:0008270=IEA} histone H3 acetylation, histone H4-K12 acetylation, histone H4-K16 acetylation, histone H4-K5 acetylation, histone H4-K8 acetylation histone acetyltransferase complex zinc ion binding Human PHF17 HPA UniProtKB {GO:0005515=PMID:12169691, GO:0006355=GO_REF:0000037, GO:0030308=PMID:12169691, GO:0006950=PMID:12169691, GO:0006915=PMID:12169691, GO:0005634=PMID:12169691, GO:0006351=GO_REF:0000037, GO:0005739=GO_REF:0000052, GO:0043981=PMID:16387653, GO:0043983=PMID:16387653, GO:0005737=PMID:12169691, GO:0043982=PMID:16387653, GO:0043966=PMID:16387653, GO:0043984=PMID:16387653, GO:0000123=PMID:16387653, GO:0008270=GO_REF:0000002} Q6IE81 Protein Jade-1 protein 20100326 {GO:0005515=IPI, GO:0006355=IEA, GO:0030308=NAS, GO:0006950=NAS, GO:0006915=NAS, GO:0005634=IDA, GO:0006351=IEA, GO:0005739=IDA, GO:0043981=IDA, GO:0043983=IDA, GO:0005737=IDA, GO:0043982=IDA, GO:0043966=IDA, GO:0043984=IDA, GO:0000123=IDA, GO:0008270=IEA} apoptotic process, histone H3 acetylation, histone H4-K12 acetylation, histone H4-K16 acetylation, histone H4-K5 acetylation, histone H4-K8 acetylation, negative regulation of cell growth, regulation of transcription, DNA-dependent, response to stress, transcription, DNA-dependent cytoplasm, histone acetyltransferase complex, mitochondrion, nucleus protein binding, zinc ion binding Human PHF19 UniProtKB UniProtKB {GO:0005515=PMID:23160351, GO:0006355=GO_REF:0000037, GO:0035098=PMID:23104054, GO:0061087=PMID:23104054, GO:0008270=GO_REF:0000002, GO:0035064=PMID:23273982, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q5T6S3 PHD finger protein 19 protein 20130222 {GO:0005515=IPI, GO:0006355=IEA, GO:0035098=IDA, GO:0061087=IMP, GO:0008270=IEA, GO:0035064=IDA, GO:0006351=IEA, GO:0016568=IEA} chromatin modification, positive regulation of histone H3-K27 methylation, regulation of transcription, DNA-dependent, transcription, DNA-dependent ESC/E(Z) complex methylated histone residue binding, protein binding, zinc ion binding Human PHF2 PINC UniProtKB {GO:0005515=PMID:21532585, GO:0032454=PMID:21532585, GO:0032452=PMID:21167174, GO:0005506=PMID:21167174, GO:0003713=PMID:21532585, GO:0005730=PMID:20129925, GO:0005634=PMID:10051327, GO:0035064=PMID:21167174, GO:0006351=GO_REF:0000037, GO:0001889=PMID:21532585, GO:0006482=PMID:21532585, GO:0061188=PMID:20129925, GO:0008270=PMID:20129925, GO:0016702=GO_REF:0000037} O75151 Lysine-specific demethylase PHF2 protein 20050308 {GO:0005515=IPI, GO:0032454=IDA, GO:0032452=IDA, GO:0005506=IDA, GO:0003713=IDA, GO:0005730=IDA, GO:0005634=TAS, GO:0035064=IDA, GO:0006351=IEA, GO:0001889=TAS, GO:0006482=IDA, GO:0061188=IMP, GO:0008270=IDA, GO:0016702=IEA} liver development, negative regulation of chromatin silencing at rDNA, protein demethylation, transcription, DNA-dependent nucleolus, nucleus histone demethylase activity, histone demethylase activity (H3-K9 specific), iron ion binding, methylated histone residue binding, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, protein binding, transcription coactivator activity, zinc ion binding Human PHF20 HPA UniProtKB {GO:0031965=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0043981=PMID:20018852, GO:0043982=PMID:20018852, GO:0043984=PMID:20018852, GO:0043996=PMID:20018852, GO:0071339=PMID:15960975, GO:0000123=PMID:20018852, GO:0043995=PMID:20018852, GO:0008270=GO_REF:0000002, GO:0046972=PMID:20018852} Q9BVI0 PHD finger protein 20 protein 20110516 {GO:0031965=IDA, GO:0006355=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA, GO:0043981=IDA, GO:0043982=IDA, GO:0043984=IDA, GO:0043996=IDA, GO:0071339=IDA, GO:0000123=IDA, GO:0043995=IDA, GO:0008270=IEA, GO:0046972=IDA} histone H4-K16 acetylation, histone H4-K5 acetylation, histone H4-K8 acetylation, regulation of transcription, DNA-dependent, transcription, DNA-dependent MLL1 complex, histone acetyltransferase complex, nuclear membrane, nucleolus, nucleus DNA binding, histone acetyltransferase activity (H4-K16 specific), histone acetyltransferase activity (H4-K5 specific), histone acetyltransferase activity (H4-K8 specific), zinc ion binding Human PHF20L1 InterPro UniProtKB {GO:0008270=GO_REF:0000002} F8W9L8 PHD finger protein 20-like protein 1 protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR001965 PHF21A Reactome UniProtKB {GO:0006355=GO_REF:0000037, GO:0000118=PMID:15325272, GO:0001967=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0003682=GO_REF:0000019, GO:0005654=Reactome:REACT_25101, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q96BD5 PHD finger protein 21A protein 20101108 {GO:0006355=IEA, GO:0000118=IDA, GO:0001967=IEA, GO:0007596=TAS, GO:0003682=IEA, GO:0005654=TAS, GO:0008270=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0016568=IEA} blood coagulation, chromatin modification, regulation of transcription, DNA-dependent, suckling behavior, transcription, DNA-dependent histone deacetylase complex, nucleoplasm, nucleus DNA binding, chromatin binding, zinc ion binding Human PHF23 InterPro UniProtKB {GO:0008270=GO_REF:0000002} Q9BUL5 PHD finger protein 23 protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR001965 PHF3 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0007275=PMID:11856869, GO:0005634=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0006351=GO_REF:0000002} Q92576 PHD finger protein 3 protein 20061026 {GO:0003674=ND, GO:0007275=NAS, GO:0005634=IEA, GO:0008270=IEA, GO:0005575=ND, GO:0006351=IEA} multicellular organismal development, transcription, DNA-dependent cellular_component, nucleus molecular_function, zinc ion binding Human PHF5A Reactome UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0003700=GO_REF:0000024, GO:0016607=GO_REF:0000024, GO:0000398=Reactome:REACT_467, GO:0005654=Reactome:REACT_1935, GO:0045893=GO_REF:0000024, GO:0003677=GO_REF:0000037, GO:0005689=PMID:15146077, GO:0016363=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0005686=PMID:12234937} Q7RTV0 PHD finger-like domain-containing protein 5A protein 20130213 {GO:0008380=TAS, GO:0010467=TAS, GO:0003700=ISS, GO:0016607=ISS, GO:0000398=TAS, GO:0005654=TAS, GO:0045893=ISS, GO:0003677=IEA, GO:0005689=IDA, GO:0016363=IEA, GO:0006351=IEA, GO:0005686=IDA} RNA splicing, gene expression, mRNA splicing, via spliceosome, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent U12-type spliceosomal complex, U2 snRNP, nuclear matrix, nuclear speck, nucleoplasm DNA binding, sequence-specific DNA binding transcription factor activity Human PHF6 HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q8IWS0 PHD finger protein 6 protein 20080205 {GO:0006355=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus, nucleus zinc ion binding Human PHF7 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002} Q9BWX1 PHD finger protein 7 protein 20110516 {GO:0005737=IDA, GO:0005794=IDA, GO:0005886=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA} Golgi apparatus, cytoplasm, nucleolus, nucleus, plasma membrane zinc ion binding Human PHF8 UniProtKB UniProtKB {GO:0005515=PMID:20622854, GO:0032454=PMID:20622854, GO:0035574=PMID:20622854, GO:0035575=PMID:20622854, GO:0032452=PMID:19843542, GO:0005506=PMID:20023638, GO:0005730=PMID:20208542, GO:0005634=PMID:20023638, GO:0035064=PMID:20622854, GO:0006351=GO_REF:0000037, GO:0051864=PMID:20622853, GO:0070544=PMID:20622853, GO:0000082=PMID:20622854, GO:0007420=GO_REF:0000024, GO:0045943=PMID:20208542, GO:0003682=PMID:20622854, GO:0071557=PMID:20622854, GO:0016706=PMID:20023638, GO:0061188=PMID:20208542, GO:0008270=PMID:20023638, GO:0016702=GO_REF:0000037, GO:0045893=PMID:20622854, GO:0071558=PMID:20622854, GO:0033169=PMID:20622854} Q9UPP1 Histone lysine demethylase PHF8 protein 20100819 {GO:0005515=IPI, GO:0032454=IDA, GO:0035574=IDA, GO:0035575=IDA, GO:0032452=IDA, GO:0005506=IDA, GO:0005730=IDA, GO:0005634=IC, GO:0035064=IDA, GO:0006351=IEA, GO:0051864=IDA, GO:0070544=IDA, GO:0000082=IMP, GO:0007420=ISS, GO:0045943=IDA, GO:0003682=IDA, GO:0071557=IDA, GO:0016706=IDA, GO:0061188=IDA, GO:0008270=IDA, GO:0016702=IEA, GO:0045893=IMP, GO:0071558=IDA, GO:0033169=IDA} G1/S transition of mitotic cell cycle, brain development, histone H3-K27 demethylation, histone H3-K36 demethylation, histone H3-K9 demethylation, histone H4-K20 demethylation, negative regulation of chromatin silencing at rDNA, positive regulation of transcription from RNA polymerase I promoter, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus, nucleus chromatin binding, histone demethylase activity, histone demethylase activity (H3-K27 specific), histone demethylase activity (H3-K36 specific), histone demethylase activity (H3-K9 specific), histone demethylase activity (H4-K20 specific), iron ion binding, methylated histone residue binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, protein binding, zinc ion binding Human UniProtKB:P0CH95 PHGDH InterPro UniProtKB {GO:0010468=GO_REF:0000019, GO:0021510=GO_REF:0000019, GO:0019530=GO_REF:0000019, GO:0008652=Reactome:REACT_238, GO:0009055=PMID:8758134, GO:0044281=Reactome:REACT_111217, GO:0022402=GO_REF:0000019, GO:0031175=GO_REF:0000019, GO:0005829=Reactome:REACT_116077, GO:0034641=Reactome:REACT_13, GO:0004617=GO_REF:0000002, GO:0051287=GO_REF:0000002, GO:0021782=GO_REF:0000019, GO:0007420=PMID:8758134, GO:0006544=GO_REF:0000019, GO:0021915=GO_REF:0000019, GO:0006564=GO_REF:0000002, GO:0006566=GO_REF:0000019, GO:0006541=GO_REF:0000019, GO:0009448=GO_REF:0000019} Q5SZU1 D-3-phosphoglycerate dehydrogenase protein 20130413 {GO:0010468=IEA, GO:0021510=IEA, GO:0019530=IEA, GO:0008652=TAS, GO:0009055=TAS, GO:0044281=TAS, GO:0022402=IEA, GO:0031175=IEA, GO:0005829=TAS, GO:0034641=TAS, GO:0004617=IEA, GO:0051287=IEA, GO:0021782=IEA, GO:0007420=TAS, GO:0006544=IEA, GO:0021915=IEA, GO:0006564=IEA, GO:0006566=IEA, GO:0006541=IEA, GO:0009448=IEA} L-serine biosynthetic process, brain development, cell cycle process, cellular amino acid biosynthetic process, cellular nitrogen compound metabolic process, gamma-aminobutyric acid metabolic process, glial cell development, glutamine metabolic process, glycine metabolic process, neural tube development, neuron projection development, regulation of gene expression, small molecule metabolic process, spinal cord development, taurine metabolic process, threonine metabolic process cytosol NAD binding, electron carrier activity, phosphoglycerate dehydrogenase activity Human InterPro:IPR006139 PHIP UniProtKB UniProtKB {GO:0005515=PMID:11018022, GO:0008286=PMID:11018022, GO:0010800=GO_REF:0000019, GO:0008284=GO_REF:0000024, GO:0043066=GO_REF:0000024, GO:0005158=PMID:11018022, GO:0045840=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0005575=GO_REF:0000015, GO:0006606=GO_REF:0000019, GO:0033138=GO_REF:0000019, GO:0043568=GO_REF:0000024, GO:0045944=GO_REF:0000019, GO:0022604=PMID:21834987, GO:0007010=PMID:21834987, GO:0070577=PMID:22464331, GO:0001932=GO_REF:0000024, GO:0045893=GO_REF:0000024, GO:0040008=GO_REF:0000019} Q8WWQ0 PH-interacting protein protein 20120706 {GO:0005515=IPI, GO:0008286=NAS, GO:0010800=IEA, GO:0008284=ISS, GO:0043066=ISS, GO:0005158=NAS, GO:0045840=ISS, GO:0005634=ISS, GO:0005575=ND, GO:0006606=IEA, GO:0033138=IEA, GO:0043568=ISS, GO:0045944=IEA, GO:0022604=IMP, GO:0007010=IMP, GO:0070577=IDA, GO:0001932=ISS, GO:0045893=ISS, GO:0040008=IEA} cytoskeleton organization, insulin receptor signaling pathway, negative regulation of apoptotic process, positive regulation of cell proliferation, positive regulation of insulin-like growth factor receptor signaling pathway, positive regulation of mitosis, positive regulation of peptidyl-serine phosphorylation, positive regulation of peptidyl-threonine phosphorylation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein import into nucleus, regulation of cell morphogenesis, regulation of growth, regulation of protein phosphorylation cellular_component, nucleus histone acetyl-lysine binding, insulin receptor binding, protein binding Human PHKA1 Reactome UniProtKB {GO:0005516=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0005975=Reactome:REACT_474, GO:0004689=PMID:8226841, GO:0005977=PMID:7874115, GO:0006006=Reactome:REACT_723, GO:0044281=Reactome:REACT_111217, GO:0006091=PMID:7874115, GO:0005980=Reactome:REACT_1008, GO:0004553=GO_REF:0000002, GO:0005829=Reactome:REACT_848} P46020 Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform protein 20130213 {GO:0005516=IEA, GO:0005886=IEA, GO:0005975=TAS, GO:0004689=TAS, GO:0005977=TAS, GO:0006006=TAS, GO:0044281=TAS, GO:0006091=TAS, GO:0005980=TAS, GO:0004553=IEA, GO:0005829=TAS} carbohydrate metabolic process, generation of precursor metabolites and energy, glucose metabolic process, glycogen catabolic process, glycogen metabolic process, small molecule metabolic process cytosol, plasma membrane calmodulin binding, hydrolase activity, hydrolyzing O-glycosyl compounds, phosphorylase kinase activity Human PHKA2 Reactome UniProtKB {GO:0005516=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0005975=Reactome:REACT_474, GO:0004689=PMID:7549948, GO:0005964=PMID:7549948, GO:0006006=Reactome:REACT_723, GO:0044281=Reactome:REACT_111217, GO:0006091=PMID:7549948, GO:0005980=Reactome:REACT_1008, GO:0006464=PMID:7549948, GO:0004553=GO_REF:0000002, GO:0005829=Reactome:REACT_1623} P46019 Phosphorylase b kinase regulatory subunit alpha, liver isoform protein 20130213 {GO:0005516=IEA, GO:0005886=IEA, GO:0005975=TAS, GO:0004689=TAS, GO:0005964=TAS, GO:0006006=TAS, GO:0044281=TAS, GO:0006091=TAS, GO:0005980=TAS, GO:0006464=TAS, GO:0004553=IEA, GO:0005829=TAS} carbohydrate metabolic process, cellular protein modification process, generation of precursor metabolites and energy, glucose metabolic process, glycogen catabolic process, small molecule metabolic process cytosol, phosphorylase kinase complex, plasma membrane calmodulin binding, hydrolase activity, hydrolyzing O-glycosyl compounds, phosphorylase kinase activity Human PHKB Reactome UniProtKB {GO:0005516=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0005975=Reactome:REACT_474, GO:0005977=PMID:9402963, GO:0006006=Reactome:REACT_723, GO:0044281=Reactome:REACT_111217, GO:0006091=PMID:9402963, GO:0005980=Reactome:REACT_1008, GO:0004553=GO_REF:0000002, GO:0005829=Reactome:REACT_1623} Q93100 Phosphorylase b kinase regulatory subunit beta protein 20130213 {GO:0005516=IEA, GO:0005886=IEA, GO:0005975=TAS, GO:0005977=TAS, GO:0006006=TAS, GO:0044281=TAS, GO:0006091=TAS, GO:0005980=TAS, GO:0004553=IEA, GO:0005829=TAS} carbohydrate metabolic process, generation of precursor metabolites and energy, glucose metabolic process, glycogen catabolic process, glycogen metabolic process, small molecule metabolic process cytosol, plasma membrane calmodulin binding, hydrolase activity, hydrolyzing O-glycosyl compounds Human PHKG1 Reactome UniProtKB {GO:0005516=GO_REF:0000037, GO:0004689=GO_REF:0000003, GO:0005975=Reactome:REACT_474, GO:0005978=GO_REF:0000002, GO:0005964=GO_REF:0000019, GO:0050321=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000019, GO:0005829=Reactome:REACT_848, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000038, GO:0006006=Reactome:REACT_723, GO:0019899=GO_REF:0000019, GO:0005980=Reactome:REACT_1008} Q16816 Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform protein 20130213 {GO:0005516=IEA, GO:0004689=IEA, GO:0005975=TAS, GO:0005978=IEA, GO:0005964=IEA, GO:0050321=IEA, GO:0044281=TAS, GO:0005524=IEA, GO:0005829=TAS, GO:0004672=IEA, GO:0004674=IEA, GO:0006006=TAS, GO:0019899=IEA, GO:0005980=TAS} carbohydrate metabolic process, glucose metabolic process, glycogen biosynthetic process, glycogen catabolic process, small molecule metabolic process cytosol, phosphorylase kinase complex ATP binding, calmodulin binding, enzyme binding, phosphorylase kinase activity, protein kinase activity, protein serine/threonine kinase activity, tau-protein kinase activity Human PHKG2 Reactome UniProtKB {GO:0005516=GO_REF:0000037, GO:0005975=Reactome:REACT_474, GO:0004689=PMID:10487978, GO:0005978=GO_REF:0000002, GO:0005964=PMID:10487978, GO:0005977=PMID:8896567, GO:0050321=PMID:8999860, GO:0044281=Reactome:REACT_111217, GO:0005575=GO_REF:0000015, GO:0006091=PMID:8896567, GO:0005524=GO_REF:0000029, GO:0005829=Reactome:REACT_1623, GO:0045819=PMID:10487978, GO:0004674=PMID:10487978, GO:0006006=Reactome:REACT_723, GO:0006468=GO_REF:0000029, GO:0005980=Reactome:REACT_1008, GO:0016772=GO_REF:0000002} P15735 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform protein 20130213 {GO:0005516=IEA, GO:0005975=TAS, GO:0004689=TAS, GO:0005978=IEA, GO:0005964=TAS, GO:0005977=TAS, GO:0050321=TAS, GO:0044281=TAS, GO:0005575=ND, GO:0006091=TAS, GO:0005524=NAS, GO:0005829=TAS, GO:0045819=TAS, GO:0004674=TAS, GO:0006006=TAS, GO:0006468=NAS, GO:0005980=TAS, GO:0016772=IEA} carbohydrate metabolic process, generation of precursor metabolites and energy, glucose metabolic process, glycogen biosynthetic process, glycogen catabolic process, glycogen metabolic process, positive regulation of glycogen catabolic process, protein phosphorylation, small molecule metabolic process cellular_component, cytosol, phosphorylase kinase complex ATP binding, calmodulin binding, phosphorylase kinase activity, protein serine/threonine kinase activity, tau-protein kinase activity, transferase activity, transferring phosphorus-containing groups Human PHLDA1 HPA UniProtKB {GO:0005515=PMID:19060904, GO:0005543=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0045210=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0006917=GO_REF:0000019, GO:0030659=GO_REF:0000039} Q8WV24 Pleckstrin homology-like domain family A member 1 protein 20100326 {GO:0005515=IPI, GO:0005543=IEA, GO:0005886=IDA, GO:0045210=IEA, GO:0005730=IDA, GO:0006915=IEA, GO:0005634=IDA, GO:0006917=IEA, GO:0030659=IEA} FasL biosynthetic process, apoptotic process, induction of apoptosis cytoplasmic vesicle membrane, nucleolus, nucleus, plasma membrane phospholipid binding, protein binding Human PHLDA2 PINC UniProtKB {GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0006915=PMID:9328465, GO:0009887=GO_REF:0000019} Q53GA4 Pleckstrin homology-like domain family A member 2 protein 20061106 {GO:0005737=IEA, GO:0005543=IEA, GO:0016020=IEA, GO:0006915=TAS, GO:0009887=IEA} apoptotic process, organ morphogenesis cytoplasm, membrane phospholipid binding Human PHLDA3 HPA UniProtKB {GO:0051898=PMID:19203586, GO:0005886=PMID:19203586, GO:0043325=PMID:19203586, GO:0005547=PMID:19203586, GO:0080025=PMID:19203586, GO:0005546=PMID:19203586, GO:0032266=PMID:19203586, GO:0006917=PMID:19203586, GO:0009653=PMID:10594239, GO:0043231=GO_REF:0000052, GO:0042771=PMID:19203586, GO:0005737=GO_REF:0000039, GO:0010314=PMID:19203586} Q9Y5J5 Pleckstrin homology-like domain family A member 3 protein 20101115 {GO:0051898=IDA, GO:0005886=IDA, GO:0043325=IDA, GO:0005547=IDA, GO:0080025=IDA, GO:0005546=IDA, GO:0032266=IDA, GO:0006917=IDA, GO:0009653=TAS, GO:0043231=IDA, GO:0042771=IDA, GO:0005737=IEA, GO:0010314=IDA} anatomical structure morphogenesis, induction of apoptosis, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, negative regulation of protein kinase B signaling cascade cytoplasm, intracellular membrane-bounded organelle, plasma membrane phosphatidylinositol-3,4,5-trisphosphate binding, phosphatidylinositol-3,4-bisphosphate binding, phosphatidylinositol-3,5-bisphosphate binding, phosphatidylinositol-3-phosphate binding, phosphatidylinositol-4,5-bisphosphate binding, phosphatidylinositol-5-phosphate binding Human PHLDB1 InterPro UniProtKB {GO:0005543=GO_REF:0000002} Q86UU1 Pleckstrin homology-like domain family B member 1 protein 20130413 {GO:0005543=IEA} phospholipid binding Human InterPro:IPR001849 PHLDB2 HPA UniProtKB {GO:0005515=PMID:20236936, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0045111=GO_REF:0000052} Q86SQ0 Pleckstrin homology-like domain family B member 2 protein 20101115 {GO:0005515=IPI, GO:0005737=IDA, GO:0005543=IEA, GO:0005886=IDA, GO:0045111=IDA} cytoplasm, intermediate filament cytoskeleton, plasma membrane phospholipid binding, protein binding Human PHLDB3 InterPro UniProtKB {GO:0005543=GO_REF:0000002} Q6NSJ2 Pleckstrin homology-like domain family B member 3 protein 20130413 {GO:0005543=IEA} phospholipid binding Human InterPro:IPR001849 PHLPP1 Reactome UniProtKB {GO:0048011=Reactome:REACT_11061, GO:0048015=Reactome:REACT_12464, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_12403, GO:0005543=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0007173=Reactome:REACT_9417, GO:0009649=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0004721=GO_REF:0000003} O60346 PH domain leucine-rich repeat-containing protein phosphatase 1 protein 20130301 {GO:0048011=TAS, GO:0048015=TAS, GO:0006915=IEA, GO:0005634=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0005543=IEA, GO:0016020=IEA, GO:0007173=TAS, GO:0009649=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:0004721=IEA} apoptotic process, entrainment of circadian clock, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling cytosol, membrane, nucleus metal ion binding, phospholipid binding, phosphoprotein phosphatase activity Human PHLPP2 LIFEdb UniProtKB {GO:0048011=Reactome:REACT_11061, GO:0042622=GO_REF:0000019, GO:0048015=Reactome:REACT_12464, GO:0005634=GO_REF:0000039, GO:0003824=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_12403, GO:0001917=GO_REF:0000019, GO:0005737=GO_REF:0000054, GO:0006470=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0004722=GO_REF:0000019} Q6ZVD8 PH domain leucine-rich repeat-containing protein phosphatase 2 protein 20100607 {GO:0048011=TAS, GO:0042622=IEA, GO:0048015=TAS, GO:0005634=IEA, GO:0003824=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0001917=IEA, GO:0005737=IDA, GO:0006470=IEA, GO:0007173=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0004722=IEA} epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, protein dephosphorylation cytoplasm, cytosol, nucleus, photoreceptor inner segment, photoreceptor outer segment membrane catalytic activity, metal ion binding, protein serine/threonine phosphatase activity Human PHOX2A BHF-UCL UniProtKB {GO:0021523=GO_REF:0000019, GO:0000790=PMID:16280598, GO:0000977=PMID:16280598, GO:0003700=GO_REF:0000002, GO:0021642=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0048485=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0043576=GO_REF:0000019, GO:0021703=GO_REF:0000019, GO:0045944=PMID:16280598, GO:0071542=PMID:19573018, GO:0021623=GO_REF:0000019, GO:0030901=GO_REF:0000019, GO:0003357=PMID:16280598} O14813 Paired mesoderm homeobox protein 2A protein 20110618 {GO:0021523=IEA, GO:0000790=IDA, GO:0000977=IDA, GO:0003700=IEA, GO:0021642=IEA, GO:0006351=IEA, GO:0048485=IEA, GO:0043565=IEA, GO:0043576=IEA, GO:0021703=IEA, GO:0045944=IDA, GO:0071542=IC, GO:0021623=IEA, GO:0030901=IEA, GO:0003357=NAS} dopaminergic neuron differentiation, locus ceruleus development, midbrain development, noradrenergic neuron differentiation, oculomotor nerve formation, positive regulation of transcription from RNA polymerase II promoter, regulation of respiratory gaseous exchange, somatic motor neuron differentiation, sympathetic nervous system development, transcription, DNA-dependent, trochlear nerve formation nuclear chromatin RNA polymerase II regulatory region sequence-specific DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human PHOX2B BHF-UCL UniProtKB {GO:0071773=GO_REF:0000024, GO:0021533=GO_REF:0000024, GO:0000790=PMID:16280598, GO:0008285=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0005634=GO_REF:0000040, GO:0061452=GO_REF:0000024, GO:0002087=GO_REF:0000024, GO:0060541=GO_REF:0000024, GO:0045944=PMID:16280598, GO:0021723=GO_REF:0000024, GO:1901166=GO_REF:0000024, GO:0048894=GO_REF:0000024, GO:0021934=GO_REF:0000024, GO:0048839=GO_REF:0000024, GO:0000977=PMID:16280598, GO:0003360=PMID:12640453, GO:0048486=GO_REF:0000024, GO:0048483=PMID:12640453, GO:0000978=PMID:16144830, GO:0006351=GO_REF:0000037, GO:0048485=GO_REF:0000024, GO:0048484=PMID:12640453, GO:0043565=GO_REF:0000002, GO:0045665=GO_REF:0000019, GO:0045666=GO_REF:0000019, GO:0071542=PMID:19573018, GO:0010001=GO_REF:0000024, GO:0001764=GO_REF:0000024, GO:0003357=GO_REF:0000024} Q99453 Paired mesoderm homeobox protein 2B protein 20110618 {GO:0071773=ISS, GO:0021533=ISS, GO:0000790=IDA, GO:0008285=IEA, GO:0003700=IEA, GO:0005634=IEA, GO:0061452=ISS, GO:0002087=ISS, GO:0060541=ISS, GO:0045944=IDA, GO:0021723=ISS, GO:1901166=ISS, GO:0048894=ISS, GO:0021934=ISS, GO:0048839=ISS, GO:0000977=IDA, GO:0003360=IEP, GO:0048486=ISS, GO:0048483=IMP, GO:0000978=IDA, GO:0006351=IEA, GO:0048485=ISS, GO:0048484=IEP, GO:0043565=IEA, GO:0045665=IEA, GO:0045666=IEA, GO:0071542=IC, GO:0010001=ISS, GO:0001764=ISS, GO:0003357=ISS} autonomic nervous system development, brainstem development, cell differentiation in hindbrain, cellular response to BMP stimulus, dopaminergic neuron differentiation, efferent axon development in a lateral line nerve, enteric nervous system development, glial cell differentiation, hindbrain tangential cell migration, inner ear development, medullary reticular formation development, negative regulation of cell proliferation, negative regulation of neuron differentiation, neural crest cell migration involved in autonomic nervous system development, neuron migration, noradrenergic neuron differentiation, parasympathetic nervous system development, positive regulation of neuron differentiation, positive regulation of transcription from RNA polymerase II promoter, regulation of respiratory gaseous exchange by neurological system process, respiratory system development, retrotrapezoid nucleus neuron differentiation, sympathetic nervous system development, transcription, DNA-dependent nuclear chromatin, nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II regulatory region sequence-specific DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human PHPT1 BHF-UCL UniProtKB {GO:0051350=PMID:20501872, GO:0008969=PMID:20501872, GO:0035774=GO_REF:0000019, GO:0050860=PMID:18796614, GO:2000147=PMID:19344975, GO:0044325=PMID:18796614, GO:0005829=PMID:20501872, GO:2000249=PMID:19344975, GO:0035971=PMID:19138678, GO:2000984=PMID:18656514, GO:0006470=PMID:20501872, GO:0019855=PMID:18796614, GO:0004721=GO_REF:0000037} Q9NRX4 14 kDa phosphohistidine phosphatase protein 20110805 {GO:0051350=IDA, GO:0008969=IDA, GO:0035774=IEA, GO:0050860=IMP, GO:2000147=IMP, GO:0044325=IPI, GO:0005829=IDA, GO:2000249=IMP, GO:0035971=IDA, GO:2000984=IDA, GO:0006470=IDA, GO:0019855=IDA, GO:0004721=IEA} negative regulation of ATP citrate synthase activity, negative regulation of T cell receptor signaling pathway, negative regulation of lyase activity, peptidyl-histidine dephosphorylation, positive regulation of cell motility, positive regulation of insulin secretion involved in cellular response to glucose stimulus, protein dephosphorylation, regulation of actin cytoskeleton reorganization cytosol calcium channel inhibitor activity, ion channel binding, phosphohistidine phosphatase activity, phosphoprotein phosphatase activity Human PHRF1 UniProtKB UniProtKB {GO:0006397=GO_REF:0000019, GO:0006366=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0070063=GO_REF:0000024} Q9P1Y6 PHD and RING finger domain-containing protein 1 protein 20081010 {GO:0006397=IEA, GO:0006366=IEA, GO:0019904=IEA, GO:0008270=IEA, GO:0070063=ISS} mRNA processing, transcription from RNA polymerase II promoter RNA polymerase binding, protein domain specific binding, zinc ion binding Human UniProtKB:Q63625 PHTF1 PINC UniProtKB {GO:0003700=PMID:10729229, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9UMS5 Putative homeodomain transcription factor 1 protein 20030904 {GO:0003700=TAS, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity Human PHTF2 LIFEdb UniProtKB {GO:0006355=GO_REF:0000037, GO:0005783=GO_REF:0000054, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8N3S3 Putative homeodomain transcription factor 2 protein 20100607 {GO:0006355=IEA, GO:0005783=IDA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent endoplasmic reticulum, nucleus DNA binding Human PHYH Reactome UniProtKB {GO:0005515=PMID:10051602, GO:0048037=PMID:10744784, GO:0031418=GO_REF:0000037, GO:0005782=Reactome:REACT_17021, GO:0097089=PMID:10744784, GO:0009055=PMID:8954107, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0005739=GO_REF:0000019, GO:0001561=Reactome:REACT_17003, GO:0048244=Reactome:REACT_17021, GO:0016702=GO_REF:0000037, GO:0044255=Reactome:REACT_16957, GO:0005777=PMID:9326939} O14832 Phytanoyl-CoA dioxygenase, peroxisomal protein 20100321 {GO:0005515=IPI, GO:0048037=IDA, GO:0031418=IEA, GO:0005782=TAS, GO:0097089=IDA, GO:0009055=TAS, GO:0044281=TAS, GO:0046872=IEA, GO:0005739=IEA, GO:0001561=TAS, GO:0048244=TAS, GO:0016702=IEA, GO:0044255=TAS, GO:0005777=IDA} cellular lipid metabolic process, fatty acid alpha-oxidation, methyl-branched fatty acid metabolic process, small molecule metabolic process mitochondrion, peroxisomal matrix, peroxisome L-ascorbic acid binding, cofactor binding, electron carrier activity, metal ion binding, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, phytanoyl-CoA dioxygenase activity, protein binding Human PHYHD1 UniProtKB UniProtKB {GO:0016702=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q5SRE7 Phytanoyl-CoA dioxygenase domain-containing protein 1 protein 20130413 {GO:0016702=IEA, GO:0046872=IEA} metal ion binding, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Human UniProtKB-KW:KW-0479 PHYHIP null null {} null null null null {} null null null PHYHIPL LIFEdb UniProtKB {GO:0005739=GO_REF:0000019, GO:0005737=GO_REF:0000054} Q96FC7 Phytanoyl-CoA hydroxylase-interacting protein-like protein 20100607 {GO:0005739=IEA, GO:0005737=IDA} cytoplasm, mitochondrion Human PI3 GOC UniProtKB {GO:0010951=PMID:2394696, GO:0004866=PMID:2394696, GO:0004867=GO_REF:0000037, GO:0005578=PMID:8476637, GO:0007620=GO_REF:0000002} P19957 Elafin protein 20130413 {GO:0010951=TAS, GO:0004866=TAS, GO:0004867=IEA, GO:0005578=TAS, GO:0007620=IEA} copulation, negative regulation of endopeptidase activity proteinaceous extracellular matrix endopeptidase inhibitor activity, serine-type endopeptidase inhibitor activity Human PI4K2A Reactome UniProtKB {GO:0004430=PMID:11279162, GO:0005515=PMID:21998198, GO:0043005=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0030425=GO_REF:0000024, GO:0005829=Reactome:REACT_121154, GO:0005739=GO_REF:0000024, GO:0002561=GO_REF:0000019, GO:0016773=GO_REF:0000002, GO:0043025=GO_REF:0000024, GO:0043204=GO_REF:0000019, GO:0030672=GO_REF:0000019, GO:0000287=PMID:11279162, GO:0035651=PMID:21998198, GO:0006661=Reactome:REACT_121025, GO:0031410=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0042734=GO_REF:0000024, GO:0035838=GO_REF:0000024, GO:0031083=PMID:21998198, GO:0005887=PMID:11279162, GO:0031901=GO_REF:0000019, GO:0044231=GO_REF:0000024, GO:0045121=PMID:11279162, GO:0006644=Reactome:REACT_121175, GO:0070382=GO_REF:0000019, GO:0005768=GO_REF:0000024} Q9BTU6 Phosphatidylinositol 4-kinase type 2-alpha protein 20130301 {GO:0004430=IDA, GO:0005515=IPI, GO:0043005=ISS, GO:0030054=IEA, GO:0044281=TAS, GO:0030425=ISS, GO:0005829=TAS, GO:0005739=ISS, GO:0002561=IEA, GO:0016773=IEA, GO:0043025=ISS, GO:0043204=IEA, GO:0030672=IEA, GO:0000287=NAS, GO:0035651=IDA, GO:0006661=TAS, GO:0031410=ISS, GO:0005524=IEA, GO:0042734=ISS, GO:0035838=ISS, GO:0031083=IDA, GO:0005887=IDA, GO:0031901=IEA, GO:0044231=ISS, GO:0045121=IDA, GO:0006644=TAS, GO:0070382=IEA, GO:0005768=ISS} basophil degranulation, phosphatidylinositol biosynthetic process, phospholipid metabolic process, small molecule metabolic process BLOC-1 complex, cell junction, cytoplasmic vesicle, cytosol, dendrite, early endosome membrane, endosome, exocytic vesicle, growing cell tip, host cell presynaptic membrane, integral to plasma membrane, membrane raft, mitochondrion, neuron projection, neuronal cell body, perikaryon, presynaptic membrane, synaptic vesicle membrane 1-phosphatidylinositol 4-kinase activity, AP-3 adaptor complex binding, ATP binding, magnesium ion binding, phosphotransferase activity, alcohol group as acceptor, protein binding Human PI4K2B HPA UniProtKB {GO:0004430=GO_REF:0000003, GO:0005737=GO_REF:0000052, GO:0006661=Reactome:REACT_121168, GO:0016020=GO_REF:0000039, GO:0016301=GO_REF:0000038, GO:0016773=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0006644=Reactome:REACT_121175, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_121159} Q8TCG2 Phosphatidylinositol 4-kinase type 2-beta protein 20080818 {GO:0004430=IEA, GO:0005737=IDA, GO:0006661=TAS, GO:0016020=IEA, GO:0016301=IEA, GO:0016773=IEA, GO:0044281=TAS, GO:0006644=TAS, GO:0005524=IEA, GO:0005829=TAS} phosphatidylinositol biosynthetic process, phospholipid metabolic process, small molecule metabolic process cytoplasm, cytosol, membrane 1-phosphatidylinositol 4-kinase activity, ATP binding, kinase activity, phosphotransferase activity, alcohol group as acceptor Human PI4KA Reactome UniProtKB {GO:0005515=PMID:14676841, GO:0004430=GO_REF:0000033, GO:0006661=Reactome:REACT_121168, GO:0005886=GO_REF:0000033, GO:0048015=GO_REF:0000002, GO:0005798=PMID:8662589, GO:0007268=PMID:8662589, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_121159, GO:0046854=GO_REF:0000002, GO:0007165=PMID:7961848, GO:0016301=GO_REF:0000038, GO:0016773=GO_REF:0000002, GO:0006644=Reactome:REACT_121175} P42356 Phosphatidylinositol 4-kinase alpha protein 20130301 {GO:0005515=IPI, GO:0004430=IBA, GO:0006661=TAS, GO:0005886=IBA, GO:0048015=IEA, GO:0005798=TAS, GO:0007268=TAS, GO:0044281=TAS, GO:0005524=IEA, GO:0005829=TAS, GO:0046854=IEA, GO:0007165=NAS, GO:0016301=IEA, GO:0016773=IEA, GO:0006644=TAS} phosphatidylinositol biosynthetic process, phosphatidylinositol phosphorylation, phosphatidylinositol-mediated signaling, phospholipid metabolic process, signal transduction, small molecule metabolic process, synaptic transmission Golgi-associated vesicle, cytosol, plasma membrane 1-phosphatidylinositol 4-kinase activity, ATP binding, kinase activity, phosphotransferase activity, alcohol group as acceptor, protein binding Human PI4KB Reactome UniProtKB {GO:0004430=Reactome:REACT_121005, GO:0048471=GO_REF:0000039, GO:0006661=Reactome:REACT_120836, GO:0048015=GO_REF:0000002, GO:0005741=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0006898=PMID:9584208, GO:0005829=Reactome:REACT_121296, GO:0007165=PMID:9020160, GO:0005737=PMID:9584208, GO:0000139=Reactome:REACT_121296, GO:0030867=GO_REF:0000039, GO:0006644=Reactome:REACT_121175, GO:0005768=PMID:9584208} Q9UBF8 Phosphatidylinositol 4-kinase beta protein 20111102 {GO:0004430=TAS, GO:0048471=IEA, GO:0006661=TAS, GO:0048015=IEA, GO:0005741=IEA, GO:0044281=TAS, GO:0005524=IEA, GO:0006898=TAS, GO:0005829=TAS, GO:0007165=TAS, GO:0005737=TAS, GO:0000139=TAS, GO:0030867=IEA, GO:0006644=TAS, GO:0005768=TAS} phosphatidylinositol biosynthetic process, phosphatidylinositol-mediated signaling, phospholipid metabolic process, receptor-mediated endocytosis, signal transduction, small molecule metabolic process Golgi membrane, cytoplasm, cytosol, endosome, mitochondrial outer membrane, perinuclear region of cytoplasm, rough endoplasmic reticulum membrane 1-phosphatidylinositol 4-kinase activity, ATP binding Human PIAS1 BHF-UCL UniProtKB {GO:0005515=PMID:18579533, GO:0019221=Reactome:REACT_25229, GO:0032436=GO_REF:0000024, GO:0005634=PMID:14752048, GO:0007283=GO_REF:0000019, GO:0050681=PMID:15572661, GO:0060334=Reactome:REACT_24980, GO:0019789=PMID:18579533, GO:0042127=GO_REF:0000024, GO:0033235=PMID:17696781, GO:0051152=GO_REF:0000019, GO:0031625=GO_REF:0000019, GO:0060333=Reactome:REACT_25078, GO:0016925=GO_REF:0000024, GO:0003714=PMID:10805787, GO:0019904=GO_REF:0000019, GO:0003713=PMID:15572661, GO:0000122=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0007259=PMID:10805787, GO:0065004=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0016607=GO_REF:0000039, GO:0016605=GO_REF:0000024, GO:0005654=Reactome:REACT_25331, GO:0008270=GO_REF:0000002, GO:0045893=PMID:15572661, GO:0019899=PMID:17087506, GO:0030521=PMID:15572661} O75925 E3 SUMO-protein ligase PIAS1 protein 20120708 {GO:0005515=IPI, GO:0019221=TAS, GO:0032436=ISS, GO:0005634=IDA, GO:0007283=IEA, GO:0050681=NAS, GO:0060334=TAS, GO:0019789=IDA, GO:0042127=ISS, GO:0033235=IDA, GO:0051152=IEA, GO:0031625=IEA, GO:0060333=TAS, GO:0016925=ISS, GO:0003714=TAS, GO:0019904=IEA, GO:0003713=NAS, GO:0000122=IEA, GO:0003676=IEA, GO:0007259=TAS, GO:0065004=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0016607=IEA, GO:0016605=ISS, GO:0005654=TAS, GO:0008270=IEA, GO:0045893=NAS, GO:0019899=IPI, GO:0030521=NAS} JAK-STAT cascade, androgen receptor signaling pathway, cytokine-mediated signaling pathway, interferon-gamma-mediated signaling pathway, negative regulation of transcription from RNA polymerase II promoter, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of protein sumoylation, positive regulation of smooth muscle cell differentiation, positive regulation of transcription, DNA-dependent, protein sumoylation, protein-DNA complex assembly, regulation of cell proliferation, regulation of interferon-gamma-mediated signaling pathway, spermatogenesis, transcription, DNA-dependent PML body, nuclear speck, nucleoplasm, nucleus DNA binding, SUMO ligase activity, androgen receptor binding, enzyme binding, nucleic acid binding, protein binding, protein domain specific binding, transcription coactivator activity, transcription corepressor activity, ubiquitin protein ligase binding, zinc ion binding Human UniProtKB:P52952 PIAS2 InterPro UniProtKB {GO:0005515=PMID:21988832, GO:0016925=PMID:22406621, GO:0003713=PMID:15572661, GO:0060766=PMID:11477070, GO:0005634=PMID:11477070, GO:0050681=PMID:15572661, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0016607=GO_REF:0000039, GO:0016605=PMID:22406621, GO:0019789=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0045893=PMID:15572661, GO:0030521=PMID:15572661} Q2TA77 E3 SUMO-protein ligase PIAS2 protein 20130413 {GO:0005515=IPI, GO:0016925=IDA, GO:0003713=NAS, GO:0060766=IDA, GO:0005634=IDA, GO:0050681=NAS, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0016607=IEA, GO:0016605=IDA, GO:0019789=IEA, GO:0008270=IEA, GO:0045893=NAS, GO:0030521=NAS} androgen receptor signaling pathway, negative regulation of androgen receptor signaling pathway, positive regulation of transcription, DNA-dependent, protein sumoylation, transcription, DNA-dependent PML body, nuclear speck, nucleus DNA binding, SUMO ligase activity, androgen receptor binding, nucleic acid binding, protein binding, transcription coactivator activity, zinc ion binding Human InterPro:IPR027228 PIAS3 UniProtKB UniProtKB {GO:0005515=PMID:11060035, GO:0006355=GO_REF:0000037, GO:0016925=GO_REF:0000024, GO:0015459=GO_REF:0000019, GO:0045202=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002, GO:0008022=PMID:14715251, GO:0006351=GO_REF:0000037, GO:0030425=GO_REF:0000019, GO:0010628=GO_REF:0000019, GO:0045838=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0047485=GO_REF:0000019, GO:0019789=GO_REF:0000019, GO:0033235=PMID:17696781, GO:0008270=GO_REF:0000002, GO:0009725=GO_REF:0000019, GO:0019899=PMID:17087506} Q9Y6X2 E3 SUMO-protein ligase PIAS3 protein 20120708 {GO:0005515=IPI, GO:0006355=IEA, GO:0016925=ISS, GO:0015459=IEA, GO:0045202=IEA, GO:0005634=IEA, GO:0003676=IEA, GO:0008022=IPI, GO:0006351=IEA, GO:0030425=IEA, GO:0010628=IEA, GO:0045838=IEA, GO:0005737=IEA, GO:0047485=IEA, GO:0019789=IEA, GO:0033235=IDA, GO:0008270=IEA, GO:0009725=IEA, GO:0019899=IPI} positive regulation of gene expression, positive regulation of membrane potential, positive regulation of protein sumoylation, protein sumoylation, regulation of transcription, DNA-dependent, response to hormone stimulus, transcription, DNA-dependent cytoplasm, dendrite, nucleus, synapse SUMO ligase activity, enzyme binding, nucleic acid binding, potassium channel regulator activity, protein C-terminus binding, protein N-terminus binding, protein binding, zinc ion binding Human UniProtKB:Q99684 PIAS4 HPA UniProtKB {GO:0005515=PMID:15383276, GO:0043065=GO_REF:0000019, GO:0016925=PMID:22508508, GO:0005730=GO_REF:0000052, GO:0032088=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0000122=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0016363=GO_REF:0000019, GO:0005737=PMID:16816390, GO:0019789=PMID:18579533, GO:0016605=GO_REF:0000039, GO:0033235=PMID:17696781, GO:0008270=PMID:9724754, GO:0016055=GO_REF:0000037, GO:0045892=PMID:11248056, GO:0031625=PMID:16816390} Q8N2W9 E3 SUMO-protein ligase PIAS4 protein 20100326 {GO:0005515=IPI, GO:0043065=IEA, GO:0016925=IMP, GO:0005730=IDA, GO:0032088=IEA, GO:0005634=IDA, GO:0000122=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0016363=IEA, GO:0005737=IDA, GO:0019789=IDA, GO:0016605=IEA, GO:0033235=IDA, GO:0008270=NAS, GO:0016055=IEA, GO:0045892=IDA, GO:0031625=IPI} Wnt receptor signaling pathway, negative regulation of NF-kappaB transcription factor activity, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of apoptotic process, positive regulation of protein sumoylation, protein sumoylation, transcription, DNA-dependent PML body, cytoplasm, nuclear matrix, nucleolus, nucleus DNA binding, SUMO ligase activity, protein binding, ubiquitin protein ligase binding, zinc ion binding NOT Human PIBF1 UniProtKB UniProtKB {GO:0005813=PMID:21399614} Q8WXW3 Progesterone-induced-blocking factor 1 protein 20110517 {GO:0005813=IDA} centrosome Human PICALM HPA UniProtKB {GO:0005515=PMID:16491119, GO:0048471=GO_REF:0000024, GO:0030132=PMID:10436022, GO:0032050=PMID:10436022, GO:0005634=PMID:16491119, GO:0007409=GO_REF:0000019, GO:0043231=GO_REF:0000052, GO:0030118=GO_REF:0000002, GO:0031623=PMID:14985334, GO:0032880=PMID:10436022, GO:0005545=GO_REF:0000024, GO:0005543=GO_REF:0000002, GO:0030276=PMID:16262731, GO:0030100=PMID:18182011, GO:0045211=GO_REF:0000024, GO:0016197=PMID:16262731, GO:0016192=PMID:8643484, GO:0030097=GO_REF:0000019, GO:0005794=GO_REF:0000039, GO:0030122=PMID:16262731, GO:0006898=PMID:10436022, GO:0042734=GO_REF:0000024, GO:0048813=GO_REF:0000019, GO:0005905=PMID:10436022, GO:0006461=PMID:8643484, GO:0048261=PMID:10436022, GO:0045893=PMID:11425879, GO:0048268=PMID:16262731} Q13492 Phosphatidylinositol-binding clathrin assembly protein protein 20101115 {GO:0005515=IPI, GO:0048471=ISS, GO:0030132=IDA, GO:0032050=IDA, GO:0005634=IDA, GO:0007409=IEA, GO:0043231=IDA, GO:0030118=IEA, GO:0031623=IMP, GO:0032880=IDA, GO:0005545=ISS, GO:0005543=IEA, GO:0030276=IDA, GO:0030100=IMP, GO:0045211=ISS, GO:0016197=IMP, GO:0016192=TAS, GO:0030097=IEA, GO:0005794=IEA, GO:0030122=IDA, GO:0006898=IDA, GO:0042734=ISS, GO:0048813=IEA, GO:0005905=IDA, GO:0006461=TAS, GO:0048261=IDA, GO:0045893=IDA, GO:0048268=IMP} axonogenesis, clathrin coat assembly, dendrite morphogenesis, endosomal transport, hemopoiesis, negative regulation of receptor-mediated endocytosis, positive regulation of transcription, DNA-dependent, protein complex assembly, receptor internalization, receptor-mediated endocytosis, regulation of endocytosis, regulation of protein localization, vesicle-mediated transport AP-2 adaptor complex, Golgi apparatus, clathrin coat, clathrin coat of coated pit, coated pit, intracellular membrane-bounded organelle, nucleus, perinuclear region of cytoplasm, postsynaptic membrane, presynaptic membrane 1-phosphatidylinositol binding, clathrin binding, clathrin heavy chain binding, phospholipid binding, protein binding Human PICK1 GOC UniProtKB {GO:0005515=PMID:16713569, GO:0048471=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0006200=GO_REF:0000024, GO:0005886=Reactome:REACT_18330, GO:0045202=GO_REF:0000024, GO:0007268=Reactome:REACT_13685, GO:0006605=GO_REF:0000019, GO:0007205=PMID:10623590, GO:0046872=GO_REF:0000037, GO:0005739=GO_REF:0000019, GO:0005737=PMID:11343649, GO:0005080=GO_REF:0000024, GO:0016887=GO_REF:0000024, GO:0043045=PMID:12138111, GO:0043046=PMID:12138111, GO:0005794=GO_REF:0000024, GO:0006890=PMID:10623590, GO:0019904=GO_REF:0000002, GO:0005102=GO_REF:0000024, GO:0008022=PMID:11343649, GO:0030666=Reactome:REACT_18330, GO:0042734=PMID:11343649, GO:0045161=PMID:11343649, GO:0043113=GO_REF:0000024, GO:0006468=GO_REF:0000024, GO:0019899=PMID:16314870, GO:0015844=PMID:11343649} Q9NRD5 PRKCA-binding protein protein 20130413 {GO:0005515=IPI, GO:0048471=ISS, GO:0030054=IEA, GO:0006200=ISS, GO:0005886=TAS, GO:0045202=ISS, GO:0007268=TAS, GO:0006605=IEA, GO:0007205=IDA, GO:0046872=IEA, GO:0005739=IEA, GO:0005737=IDA, GO:0005080=ISS, GO:0016887=ISS, GO:0043045=NAS, GO:0043046=TAS, GO:0005794=ISS, GO:0006890=NAS, GO:0019904=IEA, GO:0005102=ISS, GO:0008022=IPI, GO:0030666=TAS, GO:0042734=IDA, GO:0045161=TAS, GO:0043113=ISS, GO:0006468=ISS, GO:0019899=IPI, GO:0015844=IDA} ATP catabolic process, DNA methylation involved in embryo development, DNA methylation involved in gamete generation, monoamine transport, neuronal ion channel clustering, protein kinase C-activating G-protein coupled receptor signaling pathway, protein phosphorylation, protein targeting, receptor clustering, retrograde vesicle-mediated transport, Golgi to ER, synaptic transmission Golgi apparatus, cell junction, cytoplasm, endocytic vesicle membrane, mitochondrion, perinuclear region of cytoplasm, plasma membrane, presynaptic membrane, synapse ATPase activity, enzyme binding, metal ion binding, protein C-terminus binding, protein binding, protein domain specific binding, protein kinase C binding, receptor binding Human UniProtKB:Q62083 PID1 HPA UniProtKB {GO:2001170=PMID:20165904, GO:0090298=PMID:20165904, GO:2001171=GO_REF:0000024, GO:0046627=PMID:19079291, GO:0005730=GO_REF:0000052, GO:0051881=GO_REF:0000024, GO:0070346=PMID:16815647, GO:0005634=GO_REF:0000052, GO:0005739=GO_REF:0000052, GO:0071398=GO_REF:0000024, GO:2001274=PMID:19079291, GO:0005737=GO_REF:0000052, GO:0006112=PMID:20165904, GO:0070584=PMID:20165904, GO:0071345=GO_REF:0000024, GO:0071356=PMID:20140872, GO:0044320=GO_REF:0000019, GO:0071354=GO_REF:0000024, GO:0045444=PMID:16815647, GO:2000377=GO_REF:0000024, GO:0010635=PMID:20165904, GO:2000379=PMID:20165904} Q7Z2X4 PTB-containing, cubilin and LRP1-interacting protein protein 20110516 {GO:2001170=IMP, GO:0090298=IMP, GO:2001171=ISS, GO:0046627=IDA, GO:0005730=IDA, GO:0051881=ISS, GO:0070346=IDA, GO:0005634=IDA, GO:0005739=IDA, GO:0071398=ISS, GO:2001274=IDA, GO:0005737=IDA, GO:0006112=IC, GO:0070584=IMP, GO:0071345=ISS, GO:0071356=NAS, GO:0044320=IEA, GO:0071354=ISS, GO:0045444=IDA, GO:2000377=ISS, GO:0010635=IC, GO:2000379=IMP} cellular response to cytokine stimulus, cellular response to fatty acid, cellular response to interleukin-6, cellular response to leptin stimulus, cellular response to tumor necrosis factor, energy reserve metabolic process, fat cell differentiation, mitochondrion morphogenesis, negative regulation of ATP biosynthetic process, negative regulation of glucose import in response to insulin stimulus, negative regulation of insulin receptor signaling pathway, negative regulation of mitochondrial DNA replication, positive regulation of ATP biosynthetic process, positive regulation of fat cell proliferation, positive regulation of reactive oxygen species metabolic process, regulation of mitochondrial fusion, regulation of mitochondrial membrane potential, regulation of reactive oxygen species metabolic process cytoplasm, mitochondrion, nucleolus, nucleus Human PIDD IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0007165=PMID:10825539, GO:0005737=PMID:21726810, GO:0006915=GO_REF:0000019, GO:0005634=PMID:21726810, GO:0005123=PMID:10825539, GO:0006974=PMID:21726810} Q9HB75 p53-induced protein with a death domain protein 20130415 {GO:0005515=IPI, GO:0007165=TAS, GO:0005737=IMP, GO:0006915=IEA, GO:0005634=IMP, GO:0005123=TAS, GO:0006974=IDA} apoptotic process, response to DNA damage stimulus, signal transduction cytoplasm, nucleus death receptor binding, protein binding Human UniProtKB:Q99750 PIEZO1 UniProtKB UniProtKB {GO:0005261=GO_REF:0000024, GO:0008381=GO_REF:0000019, GO:0005886=GO_REF:0000024, GO:0050982=GO_REF:0000019, GO:0005783=PMID:20016066, GO:0033116=GO_REF:0000039, GO:0042391=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0033634=PMID:20016066, GO:0033625=PMID:20016066, GO:0006812=GO_REF:0000024} Q92508 Piezo-type mechanosensitive ion channel component 1 protein 20120516 {GO:0005261=ISS, GO:0008381=IEA, GO:0005886=ISS, GO:0050982=IEA, GO:0005783=IDA, GO:0033116=IEA, GO:0042391=IEA, GO:0005789=IEA, GO:0016021=IEA, GO:0033634=IMP, GO:0033625=IMP, GO:0006812=ISS} cation transport, detection of mechanical stimulus, positive regulation of cell-cell adhesion mediated by integrin, positive regulation of integrin activation, regulation of membrane potential endoplasmic reticulum, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment membrane, integral to membrane, plasma membrane cation channel activity, mechanically-gated ion channel activity Human UniProtKB:E2JF22 PIEZO2 UniProtKB UniProtKB {GO:0005261=GO_REF:0000019, GO:0008381=GO_REF:0000019, GO:0042391=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0006812=GO_REF:0000024} Q9H5I5 Piezo-type mechanosensitive ion channel component 2 protein 20120516 {GO:0005261=IEA, GO:0008381=IEA, GO:0042391=IEA, GO:0016021=IEA, GO:0006812=ISS} cation transport, regulation of membrane potential integral to membrane cation channel activity, mechanically-gated ion channel activity Human UniProtKB:Q8CD54 PIGA Reactome UniProtKB {GO:0005515=PMID:16162815, GO:0006501=Reactome:REACT_1853, GO:0009058=GO_REF:0000002, GO:0016757=GO_REF:0000038, GO:0016254=Reactome:REACT_952, GO:0008194=Reactome:REACT_1240, GO:0000506=PMID:16162815, GO:0017176=PMID:16162815, GO:0009893=PMID:16162815, GO:0005789=Reactome:REACT_1240, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006506=PMID:16162815, GO:0043687=Reactome:REACT_22161} P37287 Phosphatidylinositol N-acetylglucosaminyltransferase subunit A protein 20130213 {GO:0005515=IPI, GO:0006501=TAS, GO:0009058=IEA, GO:0016757=IEA, GO:0016254=TAS, GO:0008194=TAS, GO:0000506=IDA, GO:0017176=TAS, GO:0009893=TAS, GO:0005789=TAS, GO:0016021=IEA, GO:0044267=TAS, GO:0006506=TAS, GO:0043687=TAS} C-terminal protein lipidation, GPI anchor biosynthetic process, biosynthetic process, cellular protein metabolic process, positive regulation of metabolic process, post-translational protein modification, preassembly of GPI anchor in ER membrane endoplasmic reticulum membrane, glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex, integral to membrane UDP-glycosyltransferase activity, phosphatidylinositol N-acetylglucosaminyltransferase activity, protein binding, transferase activity, transferring glycosyl groups Human PIGB Reactome UniProtKB {GO:0006501=Reactome:REACT_1853, GO:0000030=PMID:8861954, GO:0016757=GO_REF:0000002, GO:0016254=Reactome:REACT_952, GO:0005789=Reactome:REACT_1308, GO:0031227=GO_REF:0000002, GO:0016021=PMID:8861954, GO:0044267=Reactome:REACT_17015, GO:0006506=PMID:8861954, GO:0043687=Reactome:REACT_22161} Q92521 GPI mannosyltransferase 3 protein 20130301 {GO:0006501=TAS, GO:0000030=IDA, GO:0016757=IEA, GO:0016254=TAS, GO:0005789=TAS, GO:0031227=IEA, GO:0016021=NAS, GO:0044267=TAS, GO:0006506=IDA, GO:0043687=TAS} C-terminal protein lipidation, GPI anchor biosynthetic process, cellular protein metabolic process, post-translational protein modification, preassembly of GPI anchor in ER membrane endoplasmic reticulum membrane, integral to membrane, intrinsic to endoplasmic reticulum membrane mannosyltransferase activity, transferase activity, transferring glycosyl groups Human PIGC Reactome UniProtKB {GO:0006501=Reactome:REACT_1853, GO:0017176=GO_REF:0000003, GO:0016254=Reactome:REACT_952, GO:0005789=Reactome:REACT_1240, GO:0016021=GO_REF:0000037, GO:0003824=PMID:8806613, GO:0044267=Reactome:REACT_17015, GO:0000506=PMID:10944123, GO:0006506=PMID:8806613, GO:0043687=Reactome:REACT_22161} Q92535 Phosphatidylinositol N-acetylglucosaminyltransferase subunit C protein 20130213 {GO:0006501=TAS, GO:0017176=IEA, GO:0016254=TAS, GO:0005789=TAS, GO:0016021=IEA, GO:0003824=TAS, GO:0044267=TAS, GO:0000506=IDA, GO:0006506=TAS, GO:0043687=TAS} C-terminal protein lipidation, GPI anchor biosynthetic process, cellular protein metabolic process, post-translational protein modification, preassembly of GPI anchor in ER membrane endoplasmic reticulum membrane, glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex, integral to membrane catalytic activity, phosphatidylinositol N-acetylglucosaminyltransferase activity Human PIGF Reactome UniProtKB {GO:0006501=Reactome:REACT_1853, GO:0004307=PMID:8463218, GO:0016254=Reactome:REACT_952, GO:0005789=Reactome:REACT_155, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006506=GO_REF:0000024, GO:0043687=Reactome:REACT_22161} Q07326 Phosphatidylinositol-glycan biosynthesis class F protein protein 20130213 {GO:0006501=TAS, GO:0004307=TAS, GO:0016254=TAS, GO:0005789=TAS, GO:0016021=IEA, GO:0044267=TAS, GO:0006506=ISS, GO:0043687=TAS} C-terminal protein lipidation, GPI anchor biosynthetic process, cellular protein metabolic process, post-translational protein modification, preassembly of GPI anchor in ER membrane endoplasmic reticulum membrane, integral to membrane ethanolaminephosphotransferase activity Human PIGG Reactome UniProtKB {GO:0006501=Reactome:REACT_1853, GO:0016780=Reactome:REACT_155, GO:0005783=PMID:15632136, GO:0051267=PMID:15632136, GO:0016254=Reactome:REACT_952, GO:0005789=Reactome:REACT_155, GO:0016021=GO_REF:0000037, GO:0003824=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0006506=PMID:15632136, GO:0016740=GO_REF:0000038, GO:0043687=Reactome:REACT_22161} Q5H8A4 GPI ethanolamine phosphate transferase 2 protein 20130213 {GO:0006501=TAS, GO:0016780=TAS, GO:0005783=IDA, GO:0051267=IDA, GO:0016254=TAS, GO:0005789=TAS, GO:0016021=IEA, GO:0003824=IEA, GO:0044267=TAS, GO:0006506=IDA, GO:0016740=IEA, GO:0043687=TAS} C-terminal protein lipidation, GPI anchor biosynthetic process, cellular protein metabolic process, post-translational protein modification, preassembly of GPI anchor in ER membrane endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane CP2 mannose-ethanolamine phosphotransferase activity, catalytic activity, phosphotransferase activity, for other substituted phosphate groups, transferase activity Human PIGH HPA UniProtKB {GO:0006501=Reactome:REACT_1853, GO:0005783=PMID:8900170, GO:0016254=Reactome:REACT_952, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003824=PMID:8900170, GO:0000506=PMID:10944123, GO:0017176=GO_REF:0000003, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0005789=Reactome:REACT_1240, GO:0044267=Reactome:REACT_17015, GO:0006464=PMID:8900170, GO:0006506=PMID:8900170, GO:0043687=Reactome:REACT_22161} Q14442 Phosphatidylinositol N-acetylglucosaminyltransferase subunit H protein 20101115 {GO:0006501=TAS, GO:0005783=TAS, GO:0016254=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0003824=TAS, GO:0000506=IDA, GO:0017176=IEA, GO:0005739=IDA, GO:0005737=IDA, GO:0005789=TAS, GO:0044267=TAS, GO:0006464=TAS, GO:0006506=TAS, GO:0043687=TAS} C-terminal protein lipidation, GPI anchor biosynthetic process, cellular protein metabolic process, cellular protein modification process, post-translational protein modification, preassembly of GPI anchor in ER membrane cytoplasm, endoplasmic reticulum, endoplasmic reticulum membrane, glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex, mitochondrion, nucleolus, nucleus catalytic activity, phosphatidylinositol N-acetylglucosaminyltransferase activity Human PIGK GOC UniProtKB {GO:0005515=PMID:11483512, GO:0006501=Reactome:REACT_1853, GO:0034235=PMID:10793132, GO:0016255=Reactome:REACT_1830, GO:0003756=PMID:12582175, GO:0030176=PMID:11483512, GO:0003923=Reactome:REACT_1777, GO:0004197=GO_REF:0000002, GO:0006457=PMID:12582175, GO:0006508=GO_REF:0000037, GO:0005789=Reactome:REACT_1777, GO:0042765=PMID:10793132, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q92643 GPI-anchor transamidase protein 20130413 {GO:0005515=IPI, GO:0006501=TAS, GO:0034235=TAS, GO:0016255=TAS, GO:0003756=TAS, GO:0030176=NAS, GO:0003923=TAS, GO:0004197=IEA, GO:0006457=TAS, GO:0006508=IEA, GO:0005789=TAS, GO:0042765=IMP, GO:0044267=TAS, GO:0043687=TAS} C-terminal protein lipidation, attachment of GPI anchor to protein, cellular protein metabolic process, post-translational protein modification, protein folding, proteolysis GPI-anchor transamidase complex, endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane GPI anchor binding, GPI-anchor transamidase activity, cysteine-type endopeptidase activity, protein binding, protein disulfide isomerase activity Human PIGL Reactome UniProtKB {GO:0006501=Reactome:REACT_1853, GO:0005783=GO_REF:0000029, GO:0016254=Reactome:REACT_952, GO:0005789=Reactome:REACT_779, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006506=PMID:10085243, GO:0000225=PMID:10085243, GO:0043687=Reactome:REACT_22161} Q9Y2B2 N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase protein 20130301 {GO:0006501=TAS, GO:0005783=NAS, GO:0016254=TAS, GO:0005789=TAS, GO:0016021=IEA, GO:0044267=TAS, GO:0006506=NAS, GO:0000225=NAS, GO:0043687=TAS} C-terminal protein lipidation, GPI anchor biosynthetic process, cellular protein metabolic process, post-translational protein modification, preassembly of GPI anchor in ER membrane endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane N-acetylglucosaminylphosphatidylinositol deacetylase activity Human PIGM Reactome UniProtKB {GO:0006501=Reactome:REACT_1853, GO:0000030=GO_REF:0000019, GO:0016254=Reactome:REACT_952, GO:0005789=Reactome:REACT_1018, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q9H3S5 GPI mannosyltransferase 1 protein 20130213 {GO:0006501=TAS, GO:0000030=IEA, GO:0016254=TAS, GO:0005789=TAS, GO:0016021=IEA, GO:0044267=TAS, GO:0043687=TAS} C-terminal protein lipidation, cellular protein metabolic process, post-translational protein modification, preassembly of GPI anchor in ER membrane endoplasmic reticulum membrane, integral to membrane mannosyltransferase activity Human PIGN Reactome UniProtKB {GO:0006501=Reactome:REACT_1853, GO:0016254=Reactome:REACT_952, GO:0005789=Reactome:REACT_464, GO:0016021=GO_REF:0000037, GO:0008484=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0016740=GO_REF:0000037, GO:0006506=GO_REF:0000002, GO:0043687=Reactome:REACT_22161} O95427 GPI ethanolamine phosphate transferase 1 protein 20130301 {GO:0006501=TAS, GO:0016254=TAS, GO:0005789=TAS, GO:0016021=IEA, GO:0008484=IEA, GO:0044267=TAS, GO:0016740=IEA, GO:0006506=IEA, GO:0043687=TAS} C-terminal protein lipidation, GPI anchor biosynthetic process, cellular protein metabolic process, post-translational protein modification, preassembly of GPI anchor in ER membrane endoplasmic reticulum membrane, integral to membrane sulfuric ester hydrolase activity, transferase activity Human PIGO Reactome UniProtKB {GO:0006501=Reactome:REACT_1853, GO:0003674=GO_REF:0000015, GO:0016254=Reactome:REACT_952, GO:0005789=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006506=GO_REF:0000024, GO:0016740=GO_REF:0000037, GO:0043687=Reactome:REACT_22161} Q8TEQ8 GPI ethanolamine phosphate transferase 3 protein 20130213 {GO:0006501=TAS, GO:0003674=ND, GO:0016254=TAS, GO:0005789=ISS, GO:0016021=IEA, GO:0044267=TAS, GO:0006506=ISS, GO:0016740=IEA, GO:0043687=TAS} C-terminal protein lipidation, GPI anchor biosynthetic process, cellular protein metabolic process, post-translational protein modification, preassembly of GPI anchor in ER membrane endoplasmic reticulum membrane, integral to membrane molecular_function, transferase activity Human PIGP Reactome UniProtKB {GO:0006501=Reactome:REACT_1853, GO:0017176=PMID:10944123, GO:0016254=Reactome:REACT_952, GO:0005789=Reactome:REACT_1240, GO:0016021=GO_REF:0000029, GO:0044267=Reactome:REACT_17015, GO:0000506=PMID:10944123, GO:0043687=Reactome:REACT_22161} P57054 Phosphatidylinositol N-acetylglucosaminyltransferase subunit P protein 20050404 {GO:0006501=TAS, GO:0017176=IDA, GO:0016254=TAS, GO:0005789=TAS, GO:0016021=NAS, GO:0044267=TAS, GO:0000506=IDA, GO:0043687=TAS} C-terminal protein lipidation, cellular protein metabolic process, post-translational protein modification, preassembly of GPI anchor in ER membrane endoplasmic reticulum membrane, glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex, integral to membrane phosphatidylinositol N-acetylglucosaminyltransferase activity Human PIGQ Reactome UniProtKB {GO:0006501=Reactome:REACT_1853, GO:0017176=GO_REF:0000003, GO:0005975=PMID:9729469, GO:0016254=Reactome:REACT_952, GO:0005789=Reactome:REACT_1240, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006506=GO_REF:0000019, GO:0000506=GO_REF:0000019, GO:0043687=Reactome:REACT_22161} Q9BRB3 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q protein 20130213 {GO:0006501=TAS, GO:0017176=IEA, GO:0005975=TAS, GO:0016254=TAS, GO:0005789=TAS, GO:0016021=IEA, GO:0044267=TAS, GO:0006506=IEA, GO:0000506=IEA, GO:0043687=TAS} C-terminal protein lipidation, GPI anchor biosynthetic process, carbohydrate metabolic process, cellular protein metabolic process, post-translational protein modification, preassembly of GPI anchor in ER membrane endoplasmic reticulum membrane, glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex, integral to membrane phosphatidylinositol N-acetylglucosaminyltransferase activity Human PIGR PINC UniProtKB {GO:0005887=PMID:2920039, GO:0005576=GO_REF:0000039} P01833 Polymeric immunoglobulin receptor protein 20030904 {GO:0005887=TAS, GO:0005576=IEA} extracellular region, integral to plasma membrane Human PIGS Reactome UniProtKB {GO:0006501=Reactome:REACT_1853, GO:0005515=PMID:11483512, GO:0016255=Reactome:REACT_1830, GO:0005789=Reactome:REACT_1777, GO:0042765=PMID:15713669, GO:0003923=PMID:11483512, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q96S52 GPI transamidase component PIG-S protein 20130213 {GO:0006501=TAS, GO:0005515=IPI, GO:0016255=TAS, GO:0005789=TAS, GO:0042765=TAS, GO:0003923=TAS, GO:0044267=TAS, GO:0043687=TAS} C-terminal protein lipidation, attachment of GPI anchor to protein, cellular protein metabolic process, post-translational protein modification GPI-anchor transamidase complex, endoplasmic reticulum membrane GPI-anchor transamidase activity, protein binding Human PIGT Reactome UniProtKB {GO:0006501=Reactome:REACT_1853, GO:0005515=PMID:11483512, GO:0030182=GO_REF:0000019, GO:0016255=Reactome:REACT_1830, GO:0005789=Reactome:REACT_1777, GO:0042765=PMID:15713669, GO:0016023=GO_REF:0000019, GO:0030176=PMID:12052837, GO:0003923=PMID:11483512, GO:0051402=GO_REF:0000019, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q969N2 GPI transamidase component PIG-T protein 20050404 {GO:0006501=TAS, GO:0005515=IPI, GO:0030182=IEA, GO:0016255=TAS, GO:0005789=TAS, GO:0042765=TAS, GO:0016023=IEA, GO:0030176=NAS, GO:0003923=TAS, GO:0051402=IEA, GO:0044267=TAS, GO:0043687=TAS} C-terminal protein lipidation, attachment of GPI anchor to protein, cellular protein metabolic process, neuron apoptotic process, neuron differentiation, post-translational protein modification GPI-anchor transamidase complex, cytoplasmic membrane-bounded vesicle, endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane GPI-anchor transamidase activity, protein binding Human PIGU Reactome UniProtKB {GO:0006501=Reactome:REACT_1853, GO:0034235=PMID:12802054, GO:0005886=PMID:15034568, GO:0016255=Reactome:REACT_1830, GO:0046425=PMID:15034568, GO:0030176=PMID:12802054, GO:0003923=PMID:12802054, GO:0005789=Reactome:REACT_1777, GO:0042765=PMID:12802054, GO:0016021=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0006506=PMID:15034568, GO:0043687=Reactome:REACT_22161} Q9H490 Phosphatidylinositol glycan anchor biosynthesis class U protein protein 20130213 {GO:0006501=TAS, GO:0034235=IMP, GO:0005886=IDA, GO:0016255=TAS, GO:0046425=IDA, GO:0030176=IC, GO:0003923=IMP, GO:0005789=TAS, GO:0042765=IDA, GO:0016021=IEA, GO:0044267=TAS, GO:0006506=IDA, GO:0043687=TAS} C-terminal protein lipidation, GPI anchor biosynthetic process, attachment of GPI anchor to protein, cellular protein metabolic process, post-translational protein modification, regulation of JAK-STAT cascade GPI-anchor transamidase complex, endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane, integral to membrane, plasma membrane GPI anchor binding, GPI-anchor transamidase activity Human PIGV Reactome UniProtKB {GO:0006501=Reactome:REACT_1853, GO:0000030=PMID:15623507, GO:0016758=GO_REF:0000002, GO:0016254=Reactome:REACT_952, GO:0005789=Reactome:REACT_1848, GO:0016021=PMID:15623507, GO:0044267=Reactome:REACT_17015, GO:0006506=PMID:15623507, GO:0043687=Reactome:REACT_22161} Q9NUD9 GPI mannosyltransferase 2 protein 20130301 {GO:0006501=TAS, GO:0000030=IGI, GO:0016758=IEA, GO:0016254=TAS, GO:0005789=TAS, GO:0016021=NAS, GO:0044267=TAS, GO:0006506=IGI, GO:0043687=TAS} C-terminal protein lipidation, GPI anchor biosynthetic process, cellular protein metabolic process, post-translational protein modification, preassembly of GPI anchor in ER membrane endoplasmic reticulum membrane, integral to membrane mannosyltransferase activity, transferase activity, transferring hexosyl groups Human PIGW Reactome UniProtKB {GO:0006501=Reactome:REACT_1853, GO:0016746=GO_REF:0000037, GO:0016254=Reactome:REACT_952, GO:0005789=Reactome:REACT_1049, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006506=GO_REF:0000002, GO:0043687=Reactome:REACT_22161} Q7Z7B1 Phosphatidylinositol-glycan biosynthesis class W protein protein 20130301 {GO:0006501=TAS, GO:0016746=IEA, GO:0016254=TAS, GO:0005789=TAS, GO:0016021=IEA, GO:0044267=TAS, GO:0006506=IEA, GO:0043687=TAS} C-terminal protein lipidation, GPI anchor biosynthetic process, cellular protein metabolic process, post-translational protein modification, preassembly of GPI anchor in ER membrane endoplasmic reticulum membrane, integral to membrane transferase activity, transferring acyl groups Human PIGX Reactome UniProtKB {GO:0006501=Reactome:REACT_1853, GO:0016254=Reactome:REACT_952, GO:0005789=Reactome:REACT_1018, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006506=GO_REF:0000002, GO:0043687=Reactome:REACT_22161} Q8TBF5 Phosphatidylinositol-glycan biosynthesis class X protein protein 20130213 {GO:0006501=TAS, GO:0016254=TAS, GO:0005789=TAS, GO:0016021=IEA, GO:0044267=TAS, GO:0006506=IEA, GO:0043687=TAS} C-terminal protein lipidation, GPI anchor biosynthetic process, cellular protein metabolic process, post-translational protein modification, preassembly of GPI anchor in ER membrane endoplasmic reticulum membrane, integral to membrane Human PIGY MGI UniProtKB {GO:0005886=PMID:16162815, GO:0005789=PMID:16162815, GO:0016021=GO_REF:0000037, GO:0000506=PMID:16162815, GO:0006506=PMID:16162815} Q3MUY2 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y protein 20071001 {GO:0005886=IDA, GO:0005789=IDA, GO:0016021=IEA, GO:0000506=IDA, GO:0006506=IDA} GPI anchor biosynthetic process endoplasmic reticulum membrane, glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex, integral to membrane, plasma membrane Human PIH1D1 BHF-UCL UniProtKB {GO:0070761=PMID:17636026, GO:0000492=PMID:17636026} Q9NWS0 PIH1 domain-containing protein 1 protein 20090629 {GO:0070761=IDA, GO:0000492=IMP} box C/D snoRNP assembly pre-snoRNP complex Human PIK3AP1 Reactome UniProtKB {GO:0036312=GO_REF:0000024, GO:0034154=GO_REF:0000024, GO:0034142=GO_REF:0000024, GO:0005886=Reactome:REACT_118601, GO:0016020=GO_REF:0000024, GO:0034134=GO_REF:0000024, GO:0050727=GO_REF:0000024, GO:0014068=GO_REF:0000024, GO:0034162=GO_REF:0000024, GO:0005829=Reactome:REACT_118566, GO:0042802=GO_REF:0000019} Q6ZUJ8 Phosphoinositide 3-kinase adapter protein 1 protein 20101103 {GO:0036312=ISS, GO:0034154=ISS, GO:0034142=ISS, GO:0005886=TAS, GO:0016020=ISS, GO:0034134=ISS, GO:0050727=ISS, GO:0014068=ISS, GO:0034162=ISS, GO:0005829=TAS, GO:0042802=IEA} positive regulation of phosphatidylinositol 3-kinase cascade, regulation of inflammatory response, toll-like receptor 2 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 7 signaling pathway, toll-like receptor 9 signaling pathway cytosol, membrane, plasma membrane identical protein binding, phosphatidylinositol 3-kinase regulatory subunit binding Human PIK3C2A Reactome UniProtKB {GO:0008286=PMID:17371240, GO:0005886=PMID:21081650, GO:0030136=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0006887=PMID:17371240, GO:0005829=Reactome:REACT_121404, GO:0005737=PMID:21081650, GO:0007173=PMID:17371240, GO:0016301=GO_REF:0000038, GO:0016303=GO_REF:0000033, GO:0005794=GO_REF:0000039, GO:0006661=Reactome:REACT_121025, GO:0048015=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0031982=PMID:21081650, GO:0014829=PMID:17371240, GO:0006897=PMID:21081650, GO:0046854=GO_REF:0000002, GO:0035005=Reactome:REACT_121403, GO:0048008=PMID:17371240, GO:0035004=PMID:17371240, GO:0005942=GO_REF:0000033, GO:0035091=GO_REF:0000002, GO:0006644=Reactome:REACT_121175, GO:0048268=PMID:17371240} O00443 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha protein 20110919 {GO:0008286=TAS, GO:0005886=IDA, GO:0030136=IEA, GO:0005634=IEA, GO:0044281=TAS, GO:0006887=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0007173=TAS, GO:0016301=IEA, GO:0016303=IBA, GO:0005794=IEA, GO:0006661=TAS, GO:0048015=IEA, GO:0005524=IEA, GO:0031982=IDA, GO:0014829=TAS, GO:0006897=IMP, GO:0046854=IEA, GO:0035005=TAS, GO:0048008=TAS, GO:0035004=TAS, GO:0005942=IBA, GO:0035091=IEA, GO:0006644=TAS, GO:0048268=TAS} clathrin coat assembly, endocytosis, epidermal growth factor receptor signaling pathway, exocytosis, insulin receptor signaling pathway, phosphatidylinositol biosynthetic process, phosphatidylinositol phosphorylation, phosphatidylinositol-mediated signaling, phospholipid metabolic process, platelet-derived growth factor receptor signaling pathway, small molecule metabolic process, vascular smooth muscle contraction Golgi apparatus, clathrin-coated vesicle, cytoplasm, cytosol, nucleus, phosphatidylinositol 3-kinase complex, plasma membrane, vesicle 1-phosphatidylinositol-3-kinase activity, 1-phosphatidylinositol-4-phosphate 3-kinase activity, ATP binding, kinase activity, phosphatidylinositol 3-kinase activity, phosphatidylinositol binding Human PIK3C2B ENSEMBL UniProtKB {GO:0005515=PMID:22128329, GO:0006661=Reactome:REACT_121025, GO:0005886=GO_REF:0000029, GO:0036092=GO_REF:0000033, GO:0005783=GO_REF:0000039, GO:0048015=GO_REF:0000002, GO:0030139=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0001727=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_121261, GO:0043231=GO_REF:0000029, GO:0008150=GO_REF:0000015, GO:0046854=GO_REF:0000002, GO:0016301=GO_REF:0000038, GO:0016303=GO_REF:0000033, GO:0016773=GO_REF:0000002, GO:0043491=GO_REF:0000019, GO:0035005=PMID:9830063, GO:0006644=Reactome:REACT_121175, GO:0035091=GO_REF:0000002, GO:0005942=GO_REF:0000033} Q5SW98 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta protein 20130413 {GO:0005515=IPI, GO:0006661=TAS, GO:0005886=NAS, GO:0036092=IBA, GO:0005783=IEA, GO:0048015=IEA, GO:0030139=IEA, GO:0005634=IEA, GO:0044281=TAS, GO:0001727=IEA, GO:0005524=IEA, GO:0005829=TAS, GO:0043231=NAS, GO:0008150=ND, GO:0046854=IEA, GO:0016301=IEA, GO:0016303=IBA, GO:0016773=IEA, GO:0043491=IEA, GO:0035005=NAS, GO:0006644=TAS, GO:0035091=IEA, GO:0005942=IBA} biological_process, phosphatidylinositol biosynthetic process, phosphatidylinositol phosphorylation, phosphatidylinositol-3-phosphate biosynthetic process, phosphatidylinositol-mediated signaling, phospholipid metabolic process, protein kinase B signaling cascade, small molecule metabolic process cytosol, endocytic vesicle, endoplasmic reticulum, intracellular membrane-bounded organelle, nucleus, phosphatidylinositol 3-kinase complex, plasma membrane 1-phosphatidylinositol-3-kinase activity, 1-phosphatidylinositol-4-phosphate 3-kinase activity, ATP binding, kinase activity, lipid kinase activity, phosphatidylinositol binding, phosphotransferase activity, alcohol group as acceptor, protein binding Human Ensembl:ENSMUSP00000076911 PIK3C2G GOC UniProtKB {GO:0006661=Reactome:REACT_121025, GO:0005886=GO_REF:0000033, GO:0036092=PMID:9878262, GO:0048015=GO_REF:0000002, GO:0016307=PMID:9878262, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_121261, GO:0046854=GO_REF:0000002, GO:0008150=GO_REF:0000015, GO:0006935=GO_REF:0000037, GO:0016301=GO_REF:0000038, GO:0016303=PMID:9878262, GO:0016773=GO_REF:0000002, GO:0035005=GO_REF:0000033, GO:0006644=Reactome:REACT_121175, GO:0035091=GO_REF:0000002, GO:0005942=GO_REF:0000033} O75747 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma protein 20130413 {GO:0006661=TAS, GO:0005886=IBA, GO:0036092=NAS, GO:0048015=IEA, GO:0016307=NAS, GO:0044281=TAS, GO:0005524=IEA, GO:0005829=TAS, GO:0046854=IEA, GO:0008150=ND, GO:0006935=IEA, GO:0016301=IEA, GO:0016303=NAS, GO:0016773=IEA, GO:0035005=IBA, GO:0006644=TAS, GO:0035091=IEA, GO:0005942=IBA} biological_process, chemotaxis, phosphatidylinositol biosynthetic process, phosphatidylinositol phosphorylation, phosphatidylinositol-3-phosphate biosynthetic process, phosphatidylinositol-mediated signaling, phospholipid metabolic process, small molecule metabolic process cytosol, phosphatidylinositol 3-kinase complex, plasma membrane 1-phosphatidylinositol-3-kinase activity, 1-phosphatidylinositol-4-phosphate 3-kinase activity, ATP binding, kinase activity, phosphatidylinositol binding, phosphatidylinositol phosphate kinase activity, phosphotransferase activity, alcohol group as acceptor Human PIK3C3 GOC UniProtKB {GO:0005515=PMID:20562859, GO:0008286=Reactome:REACT_498, GO:0044281=Reactome:REACT_111217, GO:0045022=PMID:14617358, GO:0005829=Reactome:REACT_121404, GO:0000910=PMID:20208530, GO:0016485=GO_REF:0000019, GO:0016303=PMID:20208530, GO:0016773=GO_REF:0000002, GO:0007032=GO_REF:0000019, GO:0000045=GO_REF:0000019, GO:0043201=GO_REF:0000019, GO:0006661=Reactome:REACT_120918, GO:0036092=PMID:7628435, GO:0005770=PMID:14617358, GO:0048015=GO_REF:0000019, GO:0030496=PMID:20208530, GO:0002224=Reactome:REACT_6966, GO:0005524=GO_REF:0000037, GO:0046854=GO_REF:0000002, GO:0007049=GO_REF:0000037, GO:0004672=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0050708=GO_REF:0000019, GO:0005942=GO_REF:0000033, GO:0006644=Reactome:REACT_121175, GO:0034162=Reactome:REACT_9047} Q8NEB9 Phosphatidylinositol 3-kinase catalytic subunit type 3 protein 20130413 {GO:0005515=IPI, GO:0008286=TAS, GO:0044281=TAS, GO:0045022=IMP, GO:0005829=TAS, GO:0000910=IMP, GO:0016485=IEA, GO:0016303=IMP, GO:0016773=IEA, GO:0007032=IEA, GO:0000045=IEA, GO:0043201=IEA, GO:0006661=TAS, GO:0036092=TAS, GO:0005770=IDA, GO:0048015=IEA, GO:0030496=IDA, GO:0002224=TAS, GO:0005524=IEA, GO:0046854=IEA, GO:0007049=IEA, GO:0004672=IEA, GO:0045087=TAS, GO:0050708=IEA, GO:0005942=IBA, GO:0006644=TAS, GO:0034162=TAS} autophagic vacuole assembly, cell cycle, cytokinesis, early endosome to late endosome transport, endosome organization, innate immune response, insulin receptor signaling pathway, phosphatidylinositol biosynthetic process, phosphatidylinositol phosphorylation, phosphatidylinositol-3-phosphate biosynthetic process, phosphatidylinositol-mediated signaling, phospholipid metabolic process, protein processing, regulation of protein secretion, response to leucine, small molecule metabolic process, toll-like receptor 9 signaling pathway, toll-like receptor signaling pathway cytosol, late endosome, midbody, phosphatidylinositol 3-kinase complex 1-phosphatidylinositol-3-kinase activity, ATP binding, phosphotransferase activity, alcohol group as acceptor, protein binding, protein kinase activity Human PIK3CA GOC UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005515=PMID:22402981, GO:0050852=Reactome:REACT_12526, GO:2000653=GO_REF:0000019, GO:0005886=GO_REF:0000033, GO:0031295=Reactome:REACT_19344, GO:0044029=GO_REF:0000019, GO:0043560=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0050900=Reactome:REACT_12051, GO:0060048=PMID:19147653, GO:0005829=Reactome:REACT_160316, GO:0033138=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0016301=Reactome:REACT_121331, GO:0040014=GO_REF:0000019, GO:0016303=PMID:2174051, GO:0006006=GO_REF:0000019, GO:0001944=PMID:19200708, GO:0048011=Reactome:REACT_11061, GO:0043066=GO_REF:0000019, GO:0006661=Reactome:REACT_121025, GO:0036092=PMID:2174051, GO:0048015=Reactome:REACT_12464, GO:0030168=Reactome:REACT_798, GO:0030295=GO_REF:0000019, GO:0001525=GO_REF:0000037, GO:0038028=PMID:19200708, GO:0005524=GO_REF:0000037, GO:0030027=GO_REF:0000019, GO:0046854=GO_REF:0000024, GO:0046934=Reactome:REACT_19274, GO:0004674=GO_REF:0000037, GO:0043542=PMID:19200708, GO:0008543=Reactome:REACT_9470, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0043491=GO_REF:0000019, GO:0006468=GO_REF:0000019, GO:0035005=GO_REF:0000033, GO:0035004=GO_REF:0000024, GO:0006644=Reactome:REACT_121175, GO:0005942=GO_REF:0000024, GO:0038096=Reactome:REACT_160123} P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform protein 20130413 {GO:0008286=TAS, GO:0005515=IPI, GO:0050852=TAS, GO:2000653=IEA, GO:0005886=IBA, GO:0031295=TAS, GO:0044029=IEA, GO:0043560=IEA, GO:0044281=TAS, GO:0050900=TAS, GO:0060048=TAS, GO:0005829=TAS, GO:0033138=IEA, GO:0007173=TAS, GO:0016301=TAS, GO:0040014=IEA, GO:0016303=IDA, GO:0006006=IEA, GO:0001944=TAS, GO:0048011=TAS, GO:0043066=IEA, GO:0006661=TAS, GO:0036092=IDA, GO:0048015=TAS, GO:0030168=TAS, GO:0030295=IEA, GO:0001525=IEA, GO:0038028=TAS, GO:0005524=IEA, GO:0030027=IEA, GO:0046854=ISS, GO:0046934=TAS, GO:0004674=IEA, GO:0043542=TAS, GO:0008543=TAS, GO:0007596=TAS, GO:0045087=TAS, GO:0043491=IEA, GO:0006468=IEA, GO:0035005=IBA, GO:0035004=ISS, GO:0006644=TAS, GO:0005942=ISS, GO:0038096=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, T cell costimulation, T cell receptor signaling pathway, angiogenesis, blood coagulation, cardiac muscle contraction, endothelial cell migration, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, glucose metabolic process, hypomethylation of CpG island, innate immune response, insulin receptor signaling pathway, insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade, leukocyte migration, negative regulation of apoptotic process, neurotrophin TRK receptor signaling pathway, phosphatidylinositol biosynthetic process, phosphatidylinositol phosphorylation, phosphatidylinositol-3-phosphate biosynthetic process, phosphatidylinositol-mediated signaling, phospholipid metabolic process, platelet activation, positive regulation of peptidyl-serine phosphorylation, protein kinase B signaling cascade, protein phosphorylation, regulation of genetic imprinting, regulation of multicellular organism growth, small molecule metabolic process, vasculature development cytosol, lamellipodium, phosphatidylinositol 3-kinase complex, plasma membrane 1-phosphatidylinositol-3-kinase activity, 1-phosphatidylinositol-4-phosphate 3-kinase activity, ATP binding, insulin receptor substrate binding, kinase activity, phosphatidylinositol 3-kinase activity, phosphatidylinositol-4,5-bisphosphate 3-kinase activity, protein binding, protein kinase activator activity, protein serine/threonine kinase activity Human PIK3CB IntAct UniProtKB {GO:0005515=PMID:22402981, GO:0008286=Reactome:REACT_498, GO:0050852=Reactome:REACT_12526, GO:0005886=GO_REF:0000033, GO:0043560=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0050900=Reactome:REACT_12051, GO:0005829=Reactome:REACT_160316, GO:0000187=PMID:10570282, GO:0007173=Reactome:REACT_9417, GO:0006935=PMID:10570282, GO:0040016=GO_REF:0000019, GO:0016301=GO_REF:0000038, GO:0016303=GO_REF:0000033, GO:2000369=PMID:21321382, GO:0016773=GO_REF:0000002, GO:0007156=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0006661=Reactome:REACT_121025, GO:0048015=Reactome:REACT_12464, GO:0006914=GO_REF:0000037, GO:0006874=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0005524=GO_REF:0000037, GO:0014065=PMID:21321382, GO:0070527=PMID:21035500, GO:0007165=PMID:10570282, GO:0046854=GO_REF:0000002, GO:0016477=PMID:21321382, GO:0007186=PMID:21321382, GO:0008543=Reactome:REACT_9470, GO:0007596=Reactome:REACT_604, GO:0046934=GO_REF:0000033, GO:0045087=Reactome:REACT_6802, GO:0001952=GO_REF:0000019, GO:0035005=GO_REF:0000033, GO:0035004=PMID:21035500, GO:0006644=Reactome:REACT_121175, GO:0005942=GO_REF:0000033, GO:0038096=Reactome:REACT_160123, GO:0007169=PMID:21035500, GO:0010508=PMID:21321382} P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform protein 20130415 {GO:0005515=IPI, GO:0008286=TAS, GO:0050852=TAS, GO:0005886=IBA, GO:0043560=IEA, GO:0005634=IEA, GO:0044281=TAS, GO:0050900=TAS, GO:0005829=TAS, GO:0000187=TAS, GO:0007173=TAS, GO:0006935=TAS, GO:0040016=IEA, GO:0016301=IEA, GO:0016303=IBA, GO:2000369=TAS, GO:0016773=IEA, GO:0007156=IEA, GO:0048011=TAS, GO:0006661=TAS, GO:0048015=TAS, GO:0006914=IEA, GO:0006874=IEA, GO:0030168=TAS, GO:0005524=IEA, GO:0014065=TAS, GO:0070527=TAS, GO:0007165=NAS, GO:0046854=IEA, GO:0016477=TAS, GO:0007186=TAS, GO:0008543=TAS, GO:0007596=TAS, GO:0046934=IBA, GO:0045087=TAS, GO:0001952=IEA, GO:0035005=IBA, GO:0035004=TAS, GO:0006644=TAS, GO:0005942=IBA, GO:0038096=TAS, GO:0007169=TAS, GO:0010508=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, G-protein coupled receptor signaling pathway, T cell receptor signaling pathway, activation of MAPK activity, autophagy, blood coagulation, cell migration, cellular calcium ion homeostasis, chemotaxis, embryonic cleavage, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, homophilic cell adhesion, innate immune response, insulin receptor signaling pathway, leukocyte migration, neurotrophin TRK receptor signaling pathway, phosphatidylinositol 3-kinase cascade, phosphatidylinositol biosynthetic process, phosphatidylinositol phosphorylation, phosphatidylinositol-mediated signaling, phospholipid metabolic process, platelet activation, platelet aggregation, positive regulation of autophagy, regulation of cell-matrix adhesion, regulation of clathrin-mediated endocytosis, signal transduction, small molecule metabolic process, transmembrane receptor protein tyrosine kinase signaling pathway cytosol, nucleus, phosphatidylinositol 3-kinase complex, plasma membrane 1-phosphatidylinositol-3-kinase activity, 1-phosphatidylinositol-4-phosphate 3-kinase activity, ATP binding, insulin receptor substrate binding, kinase activity, phosphatidylinositol 3-kinase activity, phosphatidylinositol-4,5-bisphosphate 3-kinase activity, phosphotransferase activity, alcohol group as acceptor, protein binding Human UniProtKB:O00459 PIK3CD UniProtKB UniProtKB {GO:0005515=PMID:22020336, GO:0050853=PMID:20940048, GO:0050852=PMID:20940048, GO:0001782=GO_REF:0000019, GO:0005886=Reactome:REACT_23869, GO:0044281=Reactome:REACT_111217, GO:0001816=PMID:20940048, GO:0010818=PMID:20940048, GO:0005829=Reactome:REACT_121297, GO:0002679=PMID:20940048, GO:0006954=PMID:20940048, GO:0007173=Reactome:REACT_9417, GO:0030101=PMID:20940048, GO:0016301=GO_REF:0000038, GO:0060374=PMID:20940048, GO:0016303=PMID:9235916, GO:0016773=GO_REF:0000002, GO:0001779=PMID:20940048, GO:0035747=PMID:20940048, GO:0072672=PMID:20940048, GO:0048011=Reactome:REACT_11061, GO:0043303=PMID:20940048, GO:0006661=Reactome:REACT_121025, GO:0036092=PMID:9235916, GO:0048015=GO_REF:0000002, GO:0030593=PMID:20940048, GO:0014065=PMID:17290298, GO:0005524=GO_REF:0000038, GO:0002250=PMID:17290298, GO:0042113=PMID:20940048, GO:0007165=PMID:9113989, GO:0046854=GO_REF:0000002, GO:0042110=PMID:20940048, GO:0030217=PMID:20940048, GO:0008543=Reactome:REACT_9470, GO:0046934=GO_REF:0000033, GO:0002551=PMID:20940048, GO:0045087=Reactome:REACT_6802, GO:0035754=PMID:20940048, GO:0006468=PMID:9113989, GO:0035005=GO_REF:0000033, GO:0035004=PMID:17290298, GO:0006644=Reactome:REACT_121175, GO:0005942=PMID:9235916} Q5SR50 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform protein 20130413 {GO:0005515=IPI, GO:0050853=TAS, GO:0050852=TAS, GO:0001782=IEA, GO:0005886=TAS, GO:0044281=TAS, GO:0001816=TAS, GO:0010818=TAS, GO:0005829=TAS, GO:0002679=TAS, GO:0006954=TAS, GO:0007173=TAS, GO:0030101=TAS, GO:0016301=IEA, GO:0060374=TAS, GO:0016303=NAS, GO:0016773=IEA, GO:0001779=TAS, GO:0035747=TAS, GO:0072672=TAS, GO:0048011=TAS, GO:0043303=TAS, GO:0006661=TAS, GO:0036092=NAS, GO:0048015=IEA, GO:0030593=TAS, GO:0014065=TAS, GO:0005524=IEA, GO:0002250=TAS, GO:0042113=TAS, GO:0007165=NAS, GO:0046854=IEA, GO:0042110=TAS, GO:0030217=TAS, GO:0008543=TAS, GO:0046934=IBA, GO:0002551=TAS, GO:0045087=TAS, GO:0035754=TAS, GO:0006468=NAS, GO:0035005=IBA, GO:0035004=TAS, GO:0006644=TAS, GO:0005942=NAS} B cell activation, B cell chemotaxis, B cell homeostasis, B cell receptor signaling pathway, T cell activation, T cell chemotaxis, T cell differentiation, T cell receptor signaling pathway, adaptive immune response, cytokine production, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, inflammatory response, innate immune response, mast cell chemotaxis, mast cell degranulation, mast cell differentiation, natural killer cell activation, natural killer cell chemotaxis, natural killer cell differentiation, neurotrophin TRK receptor signaling pathway, neutrophil chemotaxis, neutrophil extravasation, phosphatidylinositol 3-kinase cascade, phosphatidylinositol biosynthetic process, phosphatidylinositol phosphorylation, phosphatidylinositol-3-phosphate biosynthetic process, phosphatidylinositol-mediated signaling, phospholipid metabolic process, protein phosphorylation, respiratory burst involved in defense response, signal transduction, small molecule metabolic process cytosol, phosphatidylinositol 3-kinase complex, plasma membrane 1-phosphatidylinositol-3-kinase activity, 1-phosphatidylinositol-4-phosphate 3-kinase activity, ATP binding, kinase activity, phosphatidylinositol 3-kinase activity, phosphatidylinositol-4,5-bisphosphate 3-kinase activity, phosphotransferase activity, alcohol group as acceptor, protein binding Human UniProtKB-KW:KW-0418 PIK3CG IntAct UniProtKB {GO:0005515=PMID:21393242, GO:0097284=GO_REF:0000019, GO:0010897=GO_REF:0000019, GO:0001816=PMID:19075988, GO:0016303=GO_REF:0000033, GO:0035747=PMID:18278175, GO:0072672=PMID:18278175, GO:0043303=PMID:17290298, GO:0030593=PMID:17290298, GO:0030168=Reactome:REACT_798, GO:0014065=PMID:12507995, GO:0006897=GO_REF:0000037, GO:0042110=PMID:17290298, GO:0046875=PMID:11416136, GO:0007186=PMID:12507995, GO:0046934=GO_REF:0000033, GO:0045087=PMID:17290298, GO:0055118=PMID:19147653, GO:0006644=Reactome:REACT_121175, GO:0033628=PMID:18278175, GO:0051897=PMID:12507995, GO:0005886=GO_REF:0000033, GO:0044281=Reactome:REACT_111217, GO:0007204=GO_REF:0000019, GO:0010818=PMID:18278175, GO:0005829=Reactome:REACT_121297, GO:0002679=PMID:19075988, GO:0005737=PMID:12507995, GO:0006954=PMID:17290298, GO:0002675=GO_REF:0000019, GO:0042098=PMID:19075988, GO:0043406=PMID:12507995, GO:0043066=GO_REF:0000019, GO:0006661=Reactome:REACT_121025, GO:0048015=GO_REF:0000002, GO:0002407=PMID:18278175, GO:0032252=GO_REF:0000019, GO:0001525=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0002250=PMID:17290298, GO:0070527=PMID:21035500, GO:0004672=PMID:19376709, GO:0016020=PMID:12507995, GO:0004674=GO_REF:0000037, GO:0007596=Reactome:REACT_604, GO:0035005=GO_REF:0000033, GO:0006468=GO_REF:0000019, GO:0035004=PMID:17290298, GO:0005942=GO_REF:0000019, GO:0005944=PMID:12507995} P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform protein 20130415 {GO:0005515=IPI, GO:0097284=IEA, GO:0010897=IEA, GO:0001816=TAS, GO:0016303=IBA, GO:0035747=TAS, GO:0072672=TAS, GO:0043303=TAS, GO:0030593=TAS, GO:0030168=TAS, GO:0014065=IDA, GO:0006897=IEA, GO:0042110=TAS, GO:0046875=IPI, GO:0007186=IDA, GO:0046934=IBA, GO:0045087=TAS, GO:0055118=TAS, GO:0006644=TAS, GO:0033628=TAS, GO:0051897=IDA, GO:0005886=IBA, GO:0044281=TAS, GO:0007204=IEA, GO:0010818=TAS, GO:0005829=TAS, GO:0002679=TAS, GO:0005737=IDA, GO:0006954=TAS, GO:0002675=IEA, GO:0042098=TAS, GO:0043406=IDA, GO:0043066=IEA, GO:0006661=TAS, GO:0048015=IEA, GO:0002407=TAS, GO:0032252=IEA, GO:0001525=IEA, GO:0005524=IEA, GO:0002250=TAS, GO:0070527=TAS, GO:0004672=TAS, GO:0016020=IDA, GO:0004674=IEA, GO:0007596=TAS, GO:0035005=IBA, GO:0006468=IEA, GO:0035004=TAS, GO:0005942=IEA, GO:0005944=IDA} G-protein coupled receptor signaling pathway, T cell activation, T cell chemotaxis, T cell proliferation, adaptive immune response, angiogenesis, blood coagulation, cytokine production, dendritic cell chemotaxis, elevation of cytosolic calcium ion concentration, endocytosis, hepatocyte apoptotic process, inflammatory response, innate immune response, mast cell degranulation, natural killer cell chemotaxis, negative regulation of apoptotic process, negative regulation of cardiac muscle contraction, negative regulation of triglyceride catabolic process, neutrophil chemotaxis, neutrophil extravasation, phosphatidylinositol 3-kinase cascade, phosphatidylinositol biosynthetic process, phosphatidylinositol-mediated signaling, phospholipid metabolic process, platelet activation, platelet aggregation, positive regulation of MAP kinase activity, positive regulation of acute inflammatory response, positive regulation of protein kinase B signaling cascade, protein phosphorylation, regulation of cell adhesion mediated by integrin, respiratory burst involved in defense response, secretory granule localization, small molecule metabolic process 1-phosphatidylinositol-4-phosphate 3-kinase, class IB complex, cytoplasm, cytosol, membrane, phosphatidylinositol 3-kinase complex, plasma membrane 1-phosphatidylinositol-3-kinase activity, 1-phosphatidylinositol-4-phosphate 3-kinase activity, ATP binding, ephrin receptor binding, phosphatidylinositol 3-kinase activity, phosphatidylinositol-4,5-bisphosphate 3-kinase activity, protein binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB:Q13370 PIK3R1 BHF-UCL UniProtKB {GO:0005515=PMID:7782332, GO:0005159=PMID:7541045, GO:0005158=PMID:8276809, GO:0043560=GO_REF:0000024, GO:0050900=Reactome:REACT_12051, GO:0034644=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0043551=GO_REF:0000024, GO:0046326=PMID:8052599, GO:0043559=PMID:8440175, GO:0043125=PMID:10572067, GO:0030335=GO_REF:0000019, GO:0005168=PMID:15488758, GO:0019903=PMID:14699157, GO:0030168=Reactome:REACT_798, GO:0014065=PMID:7782332, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0006644=Reactome:REACT_121175, GO:0038096=Reactome:REACT_160123, GO:0043548=GO_REF:0000024, GO:0001953=GO_REF:0000019, GO:0008286=Reactome:REACT_498, GO:0050852=Reactome:REACT_12526, GO:0005886=Reactome:REACT_147854, GO:0031295=Reactome:REACT_19344, GO:0060396=PMID:7782332, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_160316, GO:0005545=GO_REF:0000029, GO:0045944=GO_REF:0000019, GO:0030183=GO_REF:0000019, GO:0005068=GO_REF:0000024, GO:0043066=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0043065=GO_REF:0000019, GO:0006661=Reactome:REACT_121025, GO:0035014=GO_REF:0000024, GO:0048015=Reactome:REACT_12464, GO:0045671=GO_REF:0000019, GO:0051531=GO_REF:0000019, GO:0007165=GO_REF:0000002, GO:0046854=GO_REF:0000024, GO:0016020=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0019048=GO_REF:0000037, GO:0048009=PMID:7782332, GO:0006468=GO_REF:0000019, GO:0005942=GO_REF:0000024, GO:0005943=GO_REF:0000024, GO:0090004=PMID:8052599} P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha protein 20120921 {GO:0005515=IPI, GO:0005159=IPI, GO:0005158=IPI, GO:0043560=ISS, GO:0050900=TAS, GO:0034644=IEA, GO:0007173=TAS, GO:0043551=ISS, GO:0046326=ISS, GO:0043559=IDA, GO:0043125=IDA, GO:0030335=IEA, GO:0005168=IPI, GO:0019903=IPI, GO:0030168=TAS, GO:0014065=IDA, GO:0008543=TAS, GO:0045087=TAS, GO:0006644=TAS, GO:0038096=TAS, GO:0043548=ISS, GO:0001953=IEA, GO:0008286=TAS, GO:0050852=TAS, GO:0005886=TAS, GO:0031295=TAS, GO:0060396=IDA, GO:0044281=TAS, GO:0005829=TAS, GO:0005545=NAS, GO:0045944=IEA, GO:0030183=IEA, GO:0005068=ISS, GO:0043066=IEA, GO:0048011=TAS, GO:0043065=IEA, GO:0006661=TAS, GO:0035014=ISS, GO:0048015=TAS, GO:0045671=IEA, GO:0051531=IEA, GO:0007165=IEA, GO:0046854=ISS, GO:0016020=IEA, GO:0007596=TAS, GO:0019048=IEA, GO:0048009=IDA, GO:0006468=IEA, GO:0005942=ISS, GO:0005943=ISS, GO:0090004=ISS} B cell differentiation, Fc-gamma receptor signaling pathway involved in phagocytosis, NFAT protein import into nucleus, T cell costimulation, T cell receptor signaling pathway, blood coagulation, cellular response to UV, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, growth hormone receptor signaling pathway, innate immune response, insulin receptor signaling pathway, insulin-like growth factor receptor signaling pathway, leukocyte migration, negative regulation of apoptotic process, negative regulation of cell-matrix adhesion, negative regulation of osteoclast differentiation, neurotrophin TRK receptor signaling pathway, phosphatidylinositol 3-kinase cascade, phosphatidylinositol biosynthetic process, phosphatidylinositol phosphorylation, phosphatidylinositol-mediated signaling, phospholipid metabolic process, platelet activation, positive regulation of apoptotic process, positive regulation of cell migration, positive regulation of establishment of protein localization to plasma membrane, positive regulation of glucose import, positive regulation of transcription from RNA polymerase II promoter, protein phosphorylation, regulation of phosphatidylinositol 3-kinase activity, signal transduction, small molecule metabolic process, virus-host interaction 1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex, cytosol, membrane, phosphatidylinositol 3-kinase complex, plasma membrane 1-phosphatidylinositol binding, ErbB-3 class receptor binding, insulin binding, insulin receptor binding, insulin receptor substrate binding, insulin-like growth factor receptor binding, neurotrophin TRKA receptor binding, phosphatidylinositol 3-kinase binding, phosphatidylinositol 3-kinase regulator activity, protein binding, protein phosphatase binding, transmembrane receptor protein tyrosine kinase adaptor activity Human UniProtKB:P23727 PIK3R2 GOC UniProtKB {GO:0005515=PMID:22402981, GO:0008286=Reactome:REACT_498, GO:0051056=Reactome:REACT_11051, GO:0050852=Reactome:REACT_12526, GO:0030971=PMID:10627473, GO:0048011=Reactome:REACT_11061, GO:0006661=Reactome:REACT_121025, GO:0036092=GO_REF:0000024, GO:0035014=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0048015=Reactome:REACT_12464, GO:0044281=Reactome:REACT_111217, GO:0050900=Reactome:REACT_12051, GO:0005829=Reactome:REACT_160316, GO:0007165=GO_REF:0000002, GO:0007173=Reactome:REACT_9417, GO:0007596=Reactome:REACT_604, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0016303=GO_REF:0000024, GO:0005942=GO_REF:0000002, GO:0006644=Reactome:REACT_121175, GO:0038096=Reactome:REACT_160123} O00459 Phosphatidylinositol 3-kinase regulatory subunit beta protein 20130413 {GO:0005515=IPI, GO:0008286=TAS, GO:0051056=TAS, GO:0050852=TAS, GO:0030971=IPI, GO:0048011=TAS, GO:0006661=TAS, GO:0036092=ISS, GO:0035014=IEA, GO:0007264=TAS, GO:0048015=TAS, GO:0044281=TAS, GO:0050900=TAS, GO:0005829=TAS, GO:0007165=IEA, GO:0007173=TAS, GO:0007596=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0016303=ISS, GO:0005942=IEA, GO:0006644=TAS, GO:0038096=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, T cell receptor signaling pathway, blood coagulation, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, leukocyte migration, neurotrophin TRK receptor signaling pathway, phosphatidylinositol biosynthetic process, phosphatidylinositol-3-phosphate biosynthetic process, phosphatidylinositol-mediated signaling, phospholipid metabolic process, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction, small molecule metabolic process cytosol, phosphatidylinositol 3-kinase complex 1-phosphatidylinositol-3-kinase activity, phosphatidylinositol 3-kinase regulator activity, protein binding, receptor tyrosine kinase binding Human UniProtKB:O08908 PIK3R3 GOC UniProtKB {GO:0008286=GO_REF:0000019, GO:0006661=Reactome:REACT_121025, GO:0046935=GO_REF:0000019, GO:0036092=PMID:9524259, GO:0035014=GO_REF:0000002, GO:0016303=PMID:9524259, GO:0044281=Reactome:REACT_111217, GO:0006644=Reactome:REACT_121175, GO:0005942=GO_REF:0000019, GO:0005829=Reactome:REACT_121297} Q92569 Phosphatidylinositol 3-kinase regulatory subunit gamma protein 20130413 {GO:0008286=IEA, GO:0006661=TAS, GO:0046935=IEA, GO:0036092=TAS, GO:0035014=IEA, GO:0016303=TAS, GO:0044281=TAS, GO:0006644=TAS, GO:0005942=IEA, GO:0005829=TAS} insulin receptor signaling pathway, phosphatidylinositol biosynthetic process, phosphatidylinositol-3-phosphate biosynthetic process, phospholipid metabolic process, small molecule metabolic process cytosol, phosphatidylinositol 3-kinase complex 1-phosphatidylinositol-3-kinase activity, 1-phosphatidylinositol-3-kinase regulator activity, phosphatidylinositol 3-kinase regulator activity Human PIK3R4 Reactome UniProtKB {GO:0005515=PMID:19270696, GO:0008286=Reactome:REACT_498, GO:0006661=Reactome:REACT_120918, GO:0005770=PMID:14617358, GO:0044281=Reactome:REACT_111217, GO:0002224=Reactome:REACT_6966, GO:0005524=GO_REF:0000029, GO:0005829=Reactome:REACT_121404, GO:0004672=PMID:8999962, GO:0004674=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0006468=PMID:8999962, GO:0006644=Reactome:REACT_121175, GO:0034162=Reactome:REACT_9047} Q99570 Phosphoinositide 3-kinase regulatory subunit 4 protein 20111102 {GO:0005515=IPI, GO:0008286=TAS, GO:0006661=TAS, GO:0005770=IDA, GO:0044281=TAS, GO:0002224=TAS, GO:0005524=NAS, GO:0005829=TAS, GO:0004672=NAS, GO:0004674=IEA, GO:0045087=TAS, GO:0006468=NAS, GO:0006644=TAS, GO:0034162=TAS} innate immune response, insulin receptor signaling pathway, phosphatidylinositol biosynthetic process, phospholipid metabolic process, protein phosphorylation, small molecule metabolic process, toll-like receptor 9 signaling pathway, toll-like receptor signaling pathway cytosol, late endosome ATP binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human PIK3R5 Reactome UniProtKB {GO:0051897=GO_REF:0000024, GO:0006661=Reactome:REACT_121025, GO:0030168=Reactome:REACT_798, GO:0005634=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0031683=GO_REF:0000024, GO:0014065=GO_REF:0000024, GO:0005829=Reactome:REACT_121297, GO:0005737=GO_REF:0000024, GO:0046935=GO_REF:0000019, GO:0007186=GO_REF:0000024, GO:0016020=GO_REF:0000024, GO:0007596=Reactome:REACT_604, GO:0043406=GO_REF:0000024, GO:0005942=GO_REF:0000019, GO:0006644=Reactome:REACT_121175, GO:0005944=GO_REF:0000024} Q8WYR1 Phosphoinositide 3-kinase regulatory subunit 5 protein 20111102 {GO:0051897=ISS, GO:0006661=TAS, GO:0030168=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0031683=ISS, GO:0014065=ISS, GO:0005829=TAS, GO:0005737=ISS, GO:0046935=IEA, GO:0007186=ISS, GO:0016020=ISS, GO:0007596=TAS, GO:0043406=ISS, GO:0005942=IEA, GO:0006644=TAS, GO:0005944=ISS} G-protein coupled receptor signaling pathway, blood coagulation, phosphatidylinositol 3-kinase cascade, phosphatidylinositol biosynthetic process, phospholipid metabolic process, platelet activation, positive regulation of MAP kinase activity, positive regulation of protein kinase B signaling cascade, small molecule metabolic process 1-phosphatidylinositol-4-phosphate 3-kinase, class IB complex, cytoplasm, cytosol, membrane, nucleus, phosphatidylinositol 3-kinase complex 1-phosphatidylinositol-3-kinase regulator activity, G-protein beta/gamma-subunit complex binding Human PIKFYVE GOC UniProtKB {GO:0005515=PMID:15046600, GO:0000285=GO_REF:0000003, GO:0034504=PMID:17909029, GO:0048471=GO_REF:0000019, GO:0043813=Reactome:REACT_120990, GO:0006661=Reactome:REACT_120918, GO:0036092=Reactome:REACT_120990, GO:0044281=Reactome:REACT_111217, GO:0031410=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0006898=PMID:14551253, GO:0005829=GO_REF:0000019, GO:0032288=GO_REF:0000019, GO:0016308=PMID:15046600, GO:0035556=GO_REF:0000002, GO:0000139=Reactome:REACT_120990, GO:0031901=Reactome:REACT_121095, GO:0031902=Reactome:REACT_121182, GO:0042147=PMID:16954148, GO:0045121=PMID:15046600, GO:0006644=Reactome:REACT_121175, GO:0044267=GO_REF:0000002, GO:0010008=PMID:17556371} Q9Y2I7 1-phosphatidylinositol 3-phosphate 5-kinase protein 20130413 {GO:0005515=IPI, GO:0000285=IEA, GO:0034504=IMP, GO:0048471=IEA, GO:0043813=TAS, GO:0006661=TAS, GO:0036092=TAS, GO:0044281=TAS, GO:0031410=IEA, GO:0005524=IEA, GO:0046872=IEA, GO:0006898=IMP, GO:0005829=IEA, GO:0032288=IEA, GO:0016308=TAS, GO:0035556=IEA, GO:0000139=TAS, GO:0031901=TAS, GO:0031902=TAS, GO:0042147=IMP, GO:0045121=IDA, GO:0006644=TAS, GO:0044267=IEA, GO:0010008=IDA} cellular protein metabolic process, intracellular signal transduction, myelin assembly, phosphatidylinositol biosynthetic process, phosphatidylinositol-3-phosphate biosynthetic process, phospholipid metabolic process, protein localization to nucleus, receptor-mediated endocytosis, retrograde transport, endosome to Golgi, small molecule metabolic process Golgi membrane, cytoplasmic vesicle, cytosol, early endosome membrane, endosome membrane, late endosome membrane, membrane raft, perinuclear region of cytoplasm 1-phosphatidylinositol-3-phosphate 5-kinase activity, 1-phosphatidylinositol-4-phosphate 5-kinase activity, ATP binding, metal ion binding, phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity, protein binding Human PILRA IntAct UniProtKB {GO:0005515=PMID:18358807, GO:0007165=PMID:10903717, GO:0005886=GO_REF:0000039, GO:0019048=GO_REF:0000037, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q9UKJ1 Paired immunoglobulin-like type 2 receptor alpha protein 20130415 {GO:0005515=IPI, GO:0007165=IDA, GO:0005886=IEA, GO:0019048=IEA, GO:0005576=IEA, GO:0016021=IEA} signal transduction, virus-host interaction extracellular region, integral to membrane, plasma membrane protein binding Human UniProtKB:P06436 PILRB UniProtKB UniProtKB {GO:0005515=PMID:10660620, GO:0007171=PMID:10660620, GO:0005887=PMID:10660620, GO:0007169=PMID:10660620} Q9UKJ0 Paired immunoglobulin-like type 2 receptor beta protein 20040507 {GO:0005515=IPI, GO:0007171=NAS, GO:0005887=NAS, GO:0007169=TAS} activation of transmembrane receptor protein tyrosine kinase activity, transmembrane receptor protein tyrosine kinase signaling pathway integral to plasma membrane protein binding Human UniProtKB:P29350 PIM1 IntAct UniProtKB {GO:0005515=PMID:16266891, GO:0043066=PMID:16186805, GO:0030145=PMID:1825810, GO:0005886=GO_REF:0000039, GO:0008283=PMID:16186805, GO:0006915=GO_REF:0000037, GO:0007275=PMID:2682662, GO:0005634=GO_REF:0000039, GO:0005524=PMID:1825810, GO:0043433=PMID:18593906, GO:0007049=GO_REF:0000037, GO:0005737=PMID:1825810, GO:0046777=PMID:16266891, GO:0004674=PMID:1825810, GO:0006468=PMID:1825810, GO:0043024=PMID:16266891, GO:0008134=PMID:18593906} P11309 Serine/threonine-protein kinase pim-1 protein 20130415 {GO:0005515=IPI, GO:0043066=IDA, GO:0030145=IDA, GO:0005886=IEA, GO:0008283=IDA, GO:0006915=IEA, GO:0007275=TAS, GO:0005634=IEA, GO:0005524=IDA, GO:0043433=IDA, GO:0007049=IEA, GO:0005737=IDA, GO:0046777=IDA, GO:0004674=IDA, GO:0006468=IDA, GO:0043024=IPI, GO:0008134=IPI} apoptotic process, cell cycle, cell proliferation, multicellular organismal development, negative regulation of apoptotic process, negative regulation of sequence-specific DNA binding transcription factor activity, protein autophosphorylation, protein phosphorylation cytoplasm, nucleus, plasma membrane ATP binding, manganese ion binding, protein binding, protein serine/threonine kinase activity, ribosomal small subunit binding, transcription factor binding Human UniProtKB:P39019 PIM2 PINC UniProtKB {GO:0043066=PMID:18675992, GO:0008285=PMID:20307683, GO:0008283=PMID:9804974, GO:0050821=PMID:20307683, GO:0009615=PMID:16548883, GO:0005524=GO_REF:0000037, GO:0000082=PMID:20307683, GO:0008637=GO_REF:0000019, GO:0004674=PMID:18593906, GO:0006468=PMID:18593906, GO:0043123=GO_REF:0000024, GO:0045893=GO_REF:0000024, GO:0010508=GO_REF:0000024, GO:0007140=PMID:9804974} Q9P1W9 Serine/threonine-protein kinase pim-2 protein 20050308 {GO:0043066=IDA, GO:0008285=IDA, GO:0008283=TAS, GO:0050821=IMP, GO:0009615=IEP, GO:0005524=IEA, GO:0000082=IDA, GO:0008637=IEA, GO:0004674=IDA, GO:0006468=IDA, GO:0043123=ISS, GO:0045893=ISS, GO:0010508=ISS, GO:0007140=TAS} G1/S transition of mitotic cell cycle, apoptotic mitochondrial changes, cell proliferation, male meiosis, negative regulation of apoptotic process, negative regulation of cell proliferation, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of autophagy, positive regulation of transcription, DNA-dependent, protein phosphorylation, protein stabilization, response to virus ATP binding, protein serine/threonine kinase activity Human PIM3 UniProtKB UniProtKB {GO:0005515=PMID:17270021, GO:0007346=PMID:17270021, GO:0043066=PMID:17270021, GO:0005737=GO_REF:0000039, GO:0007049=GO_REF:0000037, GO:0046777=GO_REF:0000019, GO:0004674=PMID:18593906, GO:0016572=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0006468=PMID:18593906, GO:0061179=GO_REF:0000024, GO:0005524=GO_REF:0000037} Q86V86 Serine/threonine-protein kinase pim-3 protein 20120708 {GO:0005515=IPI, GO:0007346=IMP, GO:0043066=IMP, GO:0005737=IEA, GO:0007049=IEA, GO:0046777=IEA, GO:0004674=IDA, GO:0016572=IEA, GO:0006915=IEA, GO:0006468=IDA, GO:0061179=ISS, GO:0005524=IEA} apoptotic process, cell cycle, histone phosphorylation, negative regulation of apoptotic process, negative regulation of insulin secretion involved in cellular response to glucose stimulus, protein autophosphorylation, protein phosphorylation, regulation of mitotic cell cycle cytoplasm ATP binding, protein binding, protein serine/threonine kinase activity Human UniProtKB:Q92934 PIN1 GOC UniProtKB {GO:0000413=PMID:19122240, GO:0005515=PMID:20179103, GO:0019221=Reactome:REACT_25229, GO:2000146=PMID:20179103, GO:0005634=PMID:20179103, GO:0060393=PMID:19122240, GO:0050815=PMID:10037602, GO:0050816=PMID:10037602, GO:0005737=GO_REF:0000039, GO:0006457=GO_REF:0000037, GO:0042127=GO_REF:0000019, GO:0051443=PMID:19122240, GO:0070373=PMID:20179103, GO:0032480=Reactome:REACT_25271, GO:0030512=PMID:19122240, GO:0007088=PMID:10391244, GO:0032465=PMID:19638580, GO:0003755=PMID:19122240, GO:0030496=PMID:19638580, GO:0031434=PMID:20179103, GO:0032794=PMID:20179103, GO:0007049=GO_REF:0000037, GO:0016607=GO_REF:0000039, GO:0032321=PMID:20179103, GO:0045087=Reactome:REACT_6802, GO:0001934=PMID:19638580, GO:0005654=Reactome:REACT_25077} Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 protein 20130413 {GO:0000413=IDA, GO:0005515=IPI, GO:0019221=TAS, GO:2000146=IDA, GO:0005634=IDA, GO:0060393=IDA, GO:0050815=IDA, GO:0050816=IPI, GO:0005737=IEA, GO:0006457=IEA, GO:0042127=IEA, GO:0051443=IDA, GO:0070373=IDA, GO:0032480=TAS, GO:0030512=IDA, GO:0007088=TAS, GO:0032465=IMP, GO:0003755=IDA, GO:0030496=IDA, GO:0031434=IPI, GO:0032794=IPI, GO:0007049=IEA, GO:0016607=IEA, GO:0032321=IMP, GO:0045087=TAS, GO:0001934=IGI, GO:0005654=TAS} cell cycle, cytokine-mediated signaling pathway, innate immune response, negative regulation of ERK1 and ERK2 cascade, negative regulation of cell motility, negative regulation of transforming growth factor beta receptor signaling pathway, negative regulation of type I interferon production, positive regulation of Rho GTPase activity, positive regulation of protein phosphorylation, positive regulation of ubiquitin-protein ligase activity, protein folding, protein peptidyl-prolyl isomerization, regulation of cell proliferation, regulation of cytokinesis, regulation of mitosis, regulation of pathway-restricted SMAD protein phosphorylation cytoplasm, midbody, nuclear speck, nucleoplasm, nucleus GTPase activating protein binding, mitogen-activated protein kinase kinase binding, peptidyl-prolyl cis-trans isomerase activity, phosphoserine binding, phosphothreonine binding, protein binding Human PIN4 UniProtKB UniProtKB {GO:0006457=GO_REF:0000037, GO:0005759=GO_REF:0000039, GO:0005819=GO_REF:0000039, GO:0005730=GO_REF:0000039, GO:0003755=GO_REF:0000003, GO:0003677=GO_REF:0000037} Q9Y237 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 protein 20130413 {GO:0006457=IEA, GO:0005759=IEA, GO:0005819=IEA, GO:0005730=IEA, GO:0003755=IEA, GO:0003677=IEA} protein folding mitochondrial matrix, nucleolus, spindle DNA binding, peptidyl-prolyl cis-trans isomerase activity Human UniProtKB-SubCell:SL-0251 PINK1 BHF-UCL UniProtKB {GO:0005515=PMID:22078885, GO:0010857=PMID:19880420, GO:0008219=GO_REF:0000037, GO:0005741=GO_REF:0000039, GO:0007243=PMID:14607334, GO:0005829=PMID:19880420, GO:0005739=PMID:15824318, GO:0043524=GO_REF:0000019, GO:0018105=PMID:19880420, GO:0016301=PMID:15824318, GO:0090200=PMID:19880420, GO:0031396=PMID:19880420, GO:0043123=PMID:19880420, GO:0055131=PMID:19880420, GO:0031625=PMID:20798600, GO:0000287=PMID:14607334, GO:0000422=PMID:20798600, GO:0097237=GO_REF:0000019, GO:0006950=PMID:15087508, GO:0005524=PMID:14607334, GO:0032226=GO_REF:0000019, GO:0004674=PMID:19880420, GO:0043254=PMID:19880420, GO:0006468=PMID:14607334, GO:0016021=GO_REF:0000037, GO:0033603=GO_REF:0000019} Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial protein 20100524 {GO:0005515=IPI, GO:0010857=IDA, GO:0008219=IEA, GO:0005741=IEA, GO:0007243=IDA, GO:0005829=IDA, GO:0005739=IDA, GO:0043524=IEA, GO:0018105=IDA, GO:0016301=IDA, GO:0090200=IMP, GO:0031396=IDA, GO:0043123=IDA, GO:0055131=IPI, GO:0031625=IPI, GO:0000287=IDA, GO:0000422=IMP, GO:0097237=IEA, GO:0006950=IDA, GO:0005524=IDA, GO:0032226=IEA, GO:0004674=IDA, GO:0043254=IDA, GO:0006468=IDA, GO:0016021=IEA, GO:0033603=IEA} cell death, cellular response to toxic substance, intracellular protein kinase cascade, mitochondrion degradation, negative regulation of neuron apoptotic process, peptidyl-serine phosphorylation, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of dopamine secretion, positive regulation of release of cytochrome c from mitochondria, positive regulation of synaptic transmission, dopaminergic, protein phosphorylation, regulation of protein complex assembly, regulation of protein ubiquitination, response to stress cytosol, integral to membrane, mitochondrial outer membrane, mitochondrion ATP binding, C3HC4-type RING finger domain binding, calcium-dependent protein kinase activity, kinase activity, magnesium ion binding, protein binding, protein serine/threonine kinase activity, ubiquitin protein ligase binding Human PINX1 GOC UniProtKB {GO:0051974=PMID:15381700, GO:0005515=PMID:19393617, GO:0000781=GO_REF:0000039, GO:0008285=PMID:11003615, GO:0010521=PMID:15381700, GO:0005819=PMID:19393617, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000228=PMID:19393617, GO:0003676=GO_REF:0000002, GO:0051972=PMID:15381700, GO:0043231=GO_REF:0000052, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0000777=GO_REF:0000039, GO:0000776=PMID:19393617, GO:0007080=PMID:19393617, GO:0007004=GO_REF:0000019, GO:0070034=PMID:15381700} Q96BK5 PIN2/TERF1-interacting telomerase inhibitor 1 protein 20130413 {GO:0051974=TAS, GO:0005515=IPI, GO:0000781=IEA, GO:0008285=NAS, GO:0010521=TAS, GO:0005819=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0000228=IDA, GO:0003676=IEA, GO:0051972=TAS, GO:0043231=IDA, GO:0005739=IDA, GO:0005737=IDA, GO:0000777=IEA, GO:0000776=IDA, GO:0007080=IMP, GO:0007004=IEA, GO:0070034=IDA} mitotic metaphase plate congression, negative regulation of cell proliferation, negative regulation of telomerase activity, regulation of telomerase activity, telomere maintenance via telomerase chromosome, telomeric region, condensed chromosome kinetochore, cytoplasm, intracellular membrane-bounded organelle, kinetochore, mitochondrion, nuclear chromosome, nucleolus, nucleus, spindle nucleic acid binding, protein binding, telomerase inhibitor activity, telomeric RNA binding Human PIP UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0016324=GO_REF:0000019, GO:0005576=GO_REF:0000029, GO:0003779=PMID:2013294} P12273 Prolactin-inducible protein protein 20061026 {GO:0008150=ND, GO:0016324=IEA, GO:0005576=NAS, GO:0003779=NAS} biological_process apical plasma membrane, extracellular region actin binding Human PIP4K2A InterPro UniProtKB {GO:0005886=GO_REF:0000039, GO:0006661=Reactome:REACT_121025, GO:0016307=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0016309=GO_REF:0000003, GO:0016308=PMID:7639683, GO:0005829=Reactome:REACT_121352, GO:0016310=GO_REF:0000029, GO:0035855=GO_REF:0000019, GO:0006644=Reactome:REACT_121175} Q5JUT3 Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha protein 20130413 {GO:0005886=IEA, GO:0006661=TAS, GO:0016307=IEA, GO:0005634=IEA, GO:0005575=ND, GO:0044281=TAS, GO:0005524=IEA, GO:0016309=IEA, GO:0016308=NAS, GO:0005829=TAS, GO:0016310=NAS, GO:0035855=IEA, GO:0006644=TAS} megakaryocyte development, phosphatidylinositol biosynthetic process, phospholipid metabolic process, phosphorylation, small molecule metabolic process cellular_component, cytosol, nucleus, plasma membrane 1-phosphatidylinositol-4-phosphate 5-kinase activity, 1-phosphatidylinositol-5-phosphate 4-kinase activity, ATP binding, phosphatidylinositol phosphate kinase activity Human InterPro:IPR002498 PIP4K2B Reactome UniProtKB {GO:0005886=GO_REF:0000039, GO:0006661=Reactome:REACT_121025, GO:0016307=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0016309=GO_REF:0000003, GO:0016308=PMID:9038203, GO:0005829=Reactome:REACT_121352, GO:0005789=GO_REF:0000039, GO:0005057=PMID:9038203, GO:0006644=Reactome:REACT_121175, GO:0007166=PMID:9038203} P78356 Phosphatidylinositol 5-phosphate 4-kinase type-2 beta protein 20111102 {GO:0005886=IEA, GO:0006661=TAS, GO:0016307=IEA, GO:0005634=IEA, GO:0044281=TAS, GO:0005524=IEA, GO:0016309=IEA, GO:0016308=IDA, GO:0005829=TAS, GO:0005789=IEA, GO:0005057=TAS, GO:0006644=TAS, GO:0007166=TAS} cell surface receptor signaling pathway, phosphatidylinositol biosynthetic process, phospholipid metabolic process, small molecule metabolic process cytosol, endoplasmic reticulum membrane, nucleus, plasma membrane 1-phosphatidylinositol-4-phosphate 5-kinase activity, 1-phosphatidylinositol-5-phosphate 4-kinase activity, ATP binding, phosphatidylinositol phosphate kinase activity, receptor signaling protein activity Human PIP4K2C HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0016020=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0016307=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037, GO:0016309=GO_REF:0000003, GO:0042802=PMID:18255255} Q8TBX8 Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma protein 20111111 {GO:0005737=IDA, GO:0016020=IEA, GO:0005730=IDA, GO:0016307=IEA, GO:0005634=IDA, GO:0005524=IEA, GO:0016309=IEA, GO:0042802=IPI} cytoplasm, membrane, nucleolus, nucleus 1-phosphatidylinositol-5-phosphate 4-kinase activity, ATP binding, identical protein binding, phosphatidylinositol phosphate kinase activity Human PIP5K1A HPA UniProtKB {GO:0005515=PMID:20660631, GO:0006909=PMID:19889969, GO:0005886=GO_REF:0000052, GO:0072661=PMID:20660631, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_121352, GO:0010761=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0048041=PMID:20660631, GO:0006650=PMID:8955136, GO:0097178=PMID:20660631, GO:0019900=PMID:15157668, GO:0006661=Reactome:REACT_121025, GO:0031532=PMID:20660631, GO:0005730=GO_REF:0000052, GO:0016307=GO_REF:0000002, GO:0032587=PMID:20660631, GO:0008654=PMID:15157668, GO:0032863=PMID:20660631, GO:0005524=GO_REF:0000037, GO:0030027=PMID:15157668, GO:0016308=PMID:18305108, GO:0007165=PMID:8955136, GO:0016310=GO_REF:0000029, GO:0016607=PMID:19889969, GO:0016477=PMID:15157668, GO:0030216=PMID:19889969, GO:0060326=PMID:20660631, GO:0005847=PMID:18305108, GO:0006644=Reactome:REACT_121175} Q99755 Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha protein 20101115 {GO:0005515=IPI, GO:0006909=TAS, GO:0005886=IDA, GO:0072661=IMP, GO:0005634=IDA, GO:0044281=TAS, GO:0005829=TAS, GO:0010761=IEA, GO:0005737=IDA, GO:0048041=IMP, GO:0006650=TAS, GO:0097178=IMP, GO:0019900=IDA, GO:0006661=TAS, GO:0031532=IMP, GO:0005730=IDA, GO:0016307=IEA, GO:0032587=IDA, GO:0008654=IDA, GO:0032863=IMP, GO:0005524=IEA, GO:0030027=IDA, GO:0016308=TAS, GO:0007165=TAS, GO:0016310=NAS, GO:0016607=TAS, GO:0016477=NAS, GO:0030216=TAS, GO:0060326=IMP, GO:0005847=IDA, GO:0006644=TAS} actin cytoskeleton reorganization, activation of Rac GTPase activity, cell chemotaxis, cell migration, fibroblast migration, focal adhesion assembly, glycerophospholipid metabolic process, keratinocyte differentiation, phagocytosis, phosphatidylinositol biosynthetic process, phospholipid biosynthetic process, phospholipid metabolic process, phosphorylation, protein targeting to plasma membrane, ruffle assembly, signal transduction, small molecule metabolic process cytoplasm, cytosol, lamellipodium, mRNA cleavage and polyadenylation specificity factor complex, nuclear speck, nucleolus, nucleus, plasma membrane, ruffle membrane 1-phosphatidylinositol-4-phosphate 5-kinase activity, ATP binding, kinase binding, phosphatidylinositol phosphate kinase activity, protein binding Human PIP5K1B Reactome UniProtKB {GO:0005515=PMID:20442317, GO:0016310=GO_REF:0000029, GO:0006661=Reactome:REACT_121025, GO:0016020=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0001931=PMID:20442317, GO:0006644=Reactome:REACT_121175, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_121352, GO:0012505=GO_REF:0000039, GO:0016308=PMID:8955136} O14986 Phosphatidylinositol 4-phosphate 5-kinase type-1 beta protein 20130301 {GO:0005515=IPI, GO:0016310=NAS, GO:0006661=TAS, GO:0016020=IEA, GO:0044281=TAS, GO:0001931=IDA, GO:0006644=TAS, GO:0005524=IEA, GO:0005829=TAS, GO:0012505=IEA, GO:0016308=NAS} phosphatidylinositol biosynthetic process, phospholipid metabolic process, phosphorylation, small molecule metabolic process cytosol, endomembrane system, membrane, uropod 1-phosphatidylinositol-4-phosphate 5-kinase activity, ATP binding, protein binding Human PIP5K1C Reactome UniProtKB {GO:0072583=PMID:19889969, GO:0006909=PMID:19889969, GO:0030036=PMID:19889969, GO:0006661=Reactome:REACT_121025, GO:0030593=PMID:19889969, GO:0034333=PMID:19889969, GO:0001891=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0032587=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0048488=PMID:19889969, GO:0005524=GO_REF:0000037, GO:0016079=PMID:19889969, GO:0005829=Reactome:REACT_121352, GO:0016308=GO_REF:0000003, GO:0012505=GO_REF:0000039, GO:0016337=PMID:19889969, GO:0007411=Reactome:REACT_18266, GO:0001931=PMID:19889969, GO:0006644=Reactome:REACT_121175, GO:0005925=PMID:19889969} O60331 Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma protein 20130301 {GO:0072583=TAS, GO:0006909=TAS, GO:0030036=TAS, GO:0006661=TAS, GO:0030593=TAS, GO:0034333=TAS, GO:0001891=IEA, GO:0005634=IEA, GO:0032587=IEA, GO:0044281=TAS, GO:0048488=TAS, GO:0005524=IEA, GO:0016079=TAS, GO:0005829=TAS, GO:0016308=IEA, GO:0012505=IEA, GO:0016337=TAS, GO:0007411=TAS, GO:0001931=TAS, GO:0006644=TAS, GO:0005925=TAS} actin cytoskeleton organization, adherens junction assembly, axon guidance, cell-cell adhesion, clathrin-mediated endocytosis, neutrophil chemotaxis, phagocytosis, phosphatidylinositol biosynthetic process, phospholipid metabolic process, small molecule metabolic process, synaptic vesicle endocytosis, synaptic vesicle exocytosis cytosol, endomembrane system, focal adhesion, nucleus, phagocytic cup, ruffle membrane, uropod 1-phosphatidylinositol-4-phosphate 5-kinase activity, ATP binding Human PIP5KL1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0016020=GO_REF:0000039, GO:0042995=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0016308=GO_REF:0000003} Q5T9C9 Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 protein 20130413 {GO:0005737=IEA, GO:0016020=IEA, GO:0042995=IEA, GO:0005524=IEA, GO:0016308=IEA} cell projection, cytoplasm, membrane 1-phosphatidylinositol-4-phosphate 5-kinase activity, ATP binding Human UniProtKB-SubCell:SL-0162 PIPOX UniProtKB UniProtKB {GO:0008115=PMID:10642506, GO:0050031=PMID:10642506, GO:0033514=PMID:10642506, GO:0005102=PMID:20178365, GO:0046653=GO_REF:0000002, GO:0016491=GO_REF:0000002, GO:0055114=PMID:10642506, GO:0005777=PMID:10642506} Q9P0Z9 Peroxisomal sarcosine oxidase protein 20120427 {GO:0008115=IDA, GO:0050031=IDA, GO:0033514=IDA, GO:0005102=IPI, GO:0046653=IEA, GO:0016491=IEA, GO:0055114=IDA, GO:0005777=IDA} L-lysine catabolic process to acetyl-CoA via L-pipecolate, oxidation-reduction process, tetrahydrofolate metabolic process peroxisome L-pipecolate oxidase activity, oxidoreductase activity, receptor binding, sarcosine oxidase activity Human UniProtKB:P50542 PIR MGI UniProtKB {GO:0003712=PMID:9079676, GO:0005515=PMID:10362352, GO:0005737=PMID:20089166, GO:0006366=PMID:9079676, GO:0008127=PMID:15951572, GO:0030224=PMID:20010624, GO:0005634=PMID:9079676, GO:0046872=PMID:20711196} O00625 Pirin protein 20120405 {GO:0003712=TAS, GO:0005515=IPI, GO:0005737=IDA, GO:0006366=TAS, GO:0008127=IDA, GO:0030224=IMP, GO:0005634=IDA, GO:0046872=IDA} monocyte differentiation, transcription from RNA polymerase II promoter cytoplasm, nucleus metal ion binding, protein binding, quercetin 2,3-dioxygenase activity, transcription cofactor activity Human PISD LIFEdb UniProtKB {GO:0005739=GO_REF:0000039, GO:0006646=Reactome:REACT_120919, GO:0005634=GO_REF:0000054, GO:0044281=Reactome:REACT_111217, GO:0008654=GO_REF:0000002, GO:0004609=GO_REF:0000003, GO:0006644=Reactome:REACT_120870, GO:0046474=Reactome:REACT_121401} Q9UG56 Phosphatidylserine decarboxylase proenzyme protein 20100607 {GO:0005739=IEA, GO:0006646=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0008654=IEA, GO:0004609=IEA, GO:0006644=TAS, GO:0046474=TAS} glycerophospholipid biosynthetic process, phosphatidylethanolamine biosynthetic process, phospholipid biosynthetic process, phospholipid metabolic process, small molecule metabolic process mitochondrion, nucleus phosphatidylserine decarboxylase activity Human PITHD1 null null {} null null null null {} null null null PITPNA Reactome UniProtKB {GO:0006629=PMID:8194769, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0008526=PMID:8194769, GO:0015914=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0008525=PMID:8194769, GO:0006810=GO_REF:0000002, GO:0035091=GO_REF:0000019, GO:0007601=PMID:7914867, GO:0070540=GO_REF:0000019, GO:0000062=GO_REF:0000019} Q00169 Phosphatidylinositol transfer protein alpha isoform protein 20100413 {GO:0006629=NAS, GO:0005622=IEA, GO:0005737=IEA, GO:0008526=TAS, GO:0015914=IEA, GO:0007411=TAS, GO:0008525=TAS, GO:0006810=IEA, GO:0035091=IEA, GO:0007601=TAS, GO:0070540=IEA, GO:0000062=IEA} axon guidance, lipid metabolic process, phospholipid transport, transport, visual perception cytoplasm, intracellular fatty-acyl-CoA binding, phosphatidylcholine transporter activity, phosphatidylinositol binding, phosphatidylinositol transporter activity, stearic acid binding Human PITPNB Reactome UniProtKB {GO:0006629=PMID:8541325, GO:0005622=GO_REF:0000002, GO:0015914=Reactome:REACT_121079, GO:0000139=Reactome:REACT_121375, GO:0005789=Reactome:REACT_121375, GO:0006810=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0006644=Reactome:REACT_121175, GO:0001701=GO_REF:0000019, GO:0046474=Reactome:REACT_121401, GO:0008289=GO_REF:0000037} P48739 Phosphatidylinositol transfer protein beta isoform protein 20110824 {GO:0006629=NAS, GO:0005622=IEA, GO:0015914=TAS, GO:0000139=TAS, GO:0005789=TAS, GO:0006810=IEA, GO:0044281=TAS, GO:0006644=TAS, GO:0001701=IEA, GO:0046474=TAS, GO:0008289=IEA} glycerophospholipid biosynthetic process, in utero embryonic development, lipid metabolic process, phospholipid metabolic process, phospholipid transport, small molecule metabolic process, transport Golgi membrane, endoplasmic reticulum membrane, intracellular lipid binding Human PITPNC1 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0005622=GO_REF:0000002, GO:0007165=PMID:10531358, GO:0005737=PMID:10531358, GO:0008526=PMID:10531358, GO:0006810=GO_REF:0000002, GO:0008289=GO_REF:0000037} Q9UKF7 Cytoplasmic phosphatidylinositol transfer protein 1 protein 20130415 {GO:0005515=IPI, GO:0005622=IEA, GO:0007165=IMP, GO:0005737=IDA, GO:0008526=IMP, GO:0006810=IEA, GO:0008289=IEA} signal transduction, transport cytoplasm, intracellular lipid binding, phosphatidylinositol transporter activity, protein binding Human UniProtKB:Q6RW13 PITPNM1 PINC UniProtKB {GO:0005811=GO_REF:0000039, GO:0006629=PMID:9680295, GO:0030496=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0032154=GO_REF:0000039, GO:0046872=GO_REF:0000037, GO:0005622=GO_REF:0000002, GO:0008526=PMID:9245688, GO:0016020=PMID:9245688, GO:0007420=PMID:9245688, GO:0032580=GO_REF:0000039, GO:0006810=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0007602=PMID:9680295} O00562 Membrane-associated phosphatidylinositol transfer protein 1 protein 20030904 {GO:0005811=IEA, GO:0006629=NAS, GO:0030496=IEA, GO:0015031=IEA, GO:0032154=IEA, GO:0046872=IEA, GO:0005622=IEA, GO:0008526=TAS, GO:0016020=TAS, GO:0007420=TAS, GO:0032580=IEA, GO:0006810=IEA, GO:0005789=IEA, GO:0007602=TAS} brain development, lipid metabolic process, phototransduction, protein transport, transport Golgi cisterna membrane, cleavage furrow, endoplasmic reticulum membrane, intracellular, lipid particle, membrane, midbody metal ion binding, phosphatidylinositol transporter activity Human PITPNM2 HPA UniProtKB {GO:0005622=GO_REF:0000019, GO:0008152=PMID:10022914, GO:0005509=PMID:10022914, GO:0006810=GO_REF:0000002, GO:0016021=PMID:10022914, GO:0046872=GO_REF:0000002, GO:0012505=GO_REF:0000039, GO:0008289=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q9BZ72 Membrane-associated phosphatidylinositol transfer protein 2 protein 20110516 {GO:0005622=IEA, GO:0008152=NAS, GO:0005509=NAS, GO:0006810=IEA, GO:0016021=NAS, GO:0046872=IEA, GO:0012505=IEA, GO:0008289=IEA, GO:0043231=IDA} metabolic process, transport endomembrane system, integral to membrane, intracellular, intracellular membrane-bounded organelle calcium ion binding, lipid binding, metal ion binding Human PITPNM3 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0030971=PMID:10022914, GO:0008526=PMID:10022914, GO:0005509=PMID:10022914, GO:0046488=PMID:10022914, GO:0006810=GO_REF:0000002, GO:0016021=PMID:10022914, GO:0012505=GO_REF:0000039, GO:0008289=GO_REF:0000037} Q9BZ71 Membrane-associated phosphatidylinositol transfer protein 3 protein 20011003 {GO:0005622=IEA, GO:0030971=TAS, GO:0008526=TAS, GO:0005509=TAS, GO:0046488=TAS, GO:0006810=IEA, GO:0016021=TAS, GO:0012505=IEA, GO:0008289=IEA} phosphatidylinositol metabolic process, transport endomembrane system, integral to membrane, intracellular calcium ion binding, lipid binding, phosphatidylinositol transporter activity, receptor tyrosine kinase binding Human PITRM1 GOC UniProtKB {GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0005759=PMID:16849325, GO:0006508=PMID:16849325, GO:0005634=GO_REF:0000052, GO:0043085=PMID:9733512, GO:0008047=PMID:9733512, GO:0004222=PMID:16849325, GO:0003824=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q5JRX3 Presequence protease, mitochondrial protein 20130413 {GO:0005739=IDA, GO:0005737=IDA, GO:0005759=IDA, GO:0006508=IMP, GO:0005634=IDA, GO:0043085=TAS, GO:0008047=TAS, GO:0004222=IMP, GO:0003824=IEA, GO:0046872=IEA} positive regulation of catalytic activity, proteolysis cytoplasm, mitochondrial matrix, mitochondrion, nucleus catalytic activity, enzyme activator activity, metal ion binding, metalloendopeptidase activity Human PITX1 HPA UniProtKB {GO:0000988=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0051216=GO_REF:0000019, GO:0021983=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000040, GO:0009653=PMID:9070926, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0001501=PMID:9070926, GO:0005737=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0035116=GO_REF:0000019, GO:0014707=GO_REF:0000019, GO:0048625=GO_REF:0000019} P78337 Pituitary homeobox 1 protein 20081203 {GO:0000988=IEA, GO:0005667=IEA, GO:0003700=IEA, GO:0051216=IEA, GO:0021983=IEA, GO:0005730=IDA, GO:0005634=IEA, GO:0009653=TAS, GO:0006351=IEA, GO:0043565=IEA, GO:0001501=TAS, GO:0005737=IEA, GO:0045944=IEA, GO:0035116=IEA, GO:0014707=IEA, GO:0048625=IEA} anatomical structure morphogenesis, branchiomeric skeletal muscle development, cartilage development, embryonic hindlimb morphogenesis, myoblast fate commitment, pituitary gland development, positive regulation of transcription from RNA polymerase II promoter, skeletal system development, transcription, DNA-dependent cytoplasm, nucleolus, nucleus, transcription factor complex protein binding transcription factor activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human PITX2 BHF-UCL UniProtKB {GO:0060577=GO_REF:0000019, GO:0060578=GO_REF:0000019, GO:0003700=PMID:15385555, GO:0033189=GO_REF:0000019, GO:0003350=GO_REF:0000019, GO:0048536=GO_REF:0000024, GO:0035886=GO_REF:0000019, GO:0031076=GO_REF:0000019, GO:0035993=PMID:18312615, GO:0016055=GO_REF:0000019, GO:2000288=GO_REF:0000019, GO:0055009=GO_REF:0000019, GO:0030334=GO_REF:0000019, GO:0001102=PMID:9685346, GO:0000976=PMID:9685346, GO:0001105=PMID:9685346, GO:0003171=GO_REF:0000019, GO:0007520=GO_REF:0000019, GO:0007275=GO_REF:0000038, GO:0000978=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0031490=GO_REF:0000019, GO:0002074=GO_REF:0000019, GO:0043388=GO_REF:0000019, GO:0055015=GO_REF:0000019, GO:0061325=GO_REF:0000024, GO:0008134=PMID:15385555, GO:0035315=PMID:19251162, GO:0007368=GO_REF:0000024, GO:0005634=PMID:19251162, GO:0061072=PMID:9437321, GO:0070986=GO_REF:0000024, GO:0060127=PMID:10372733, GO:0060126=PMID:10372733, GO:0005737=GO_REF:0000019, GO:0030182=GO_REF:0000019, GO:0045944=PMID:19251162, GO:0042476=PMID:14630904, GO:0042475=GO_REF:0000019, GO:0043010=PMID:9618168, GO:0009725=GO_REF:0000019, GO:0005667=PMID:15385555, GO:0001569=GO_REF:0000019, GO:0006355=PMID:15385555, GO:0060412=GO_REF:0000019, GO:0021855=GO_REF:0000019, GO:0003677=GO_REF:0000002, GO:0043565=GO_REF:0000002, GO:0060460=GO_REF:0000019, GO:0008585=GO_REF:0000019, GO:0001077=GO_REF:0000019, GO:0021763=GO_REF:0000019, GO:0048557=GO_REF:0000019, GO:0035116=GO_REF:0000019, GO:0003253=GO_REF:0000024, GO:0001764=GO_REF:0000019, GO:0001570=GO_REF:0000019, GO:0008584=GO_REF:0000019, GO:0061031=GO_REF:0000019} Q99697 Pituitary homeobox 2 protein 20120517 {GO:0060577=IEA, GO:0060578=IEA, GO:0003700=IDA, GO:0033189=IEA, GO:0003350=IEA, GO:0048536=ISS, GO:0035886=IEA, GO:0031076=IEA, GO:0035993=IMP, GO:0016055=IEA, GO:2000288=IEA, GO:0055009=IEA, GO:0030334=IEA, GO:0001102=IPI, GO:0000976=IDA, GO:0001105=IDA, GO:0003171=IEA, GO:0007520=IEA, GO:0007275=IEA, GO:0000978=IEA, GO:0001701=IEA, GO:0031490=IEA, GO:0002074=IEA, GO:0043388=IEA, GO:0055015=IEA, GO:0061325=ISS, GO:0008134=IPI, GO:0035315=IC, GO:0007368=ISS, GO:0005634=IDA, GO:0061072=IMP, GO:0070986=ISS, GO:0060127=TAS, GO:0060126=TAS, GO:0005737=IEA, GO:0030182=IEA, GO:0045944=IDA, GO:0042476=IMP, GO:0042475=IEA, GO:0043010=IMP, GO:0009725=IEA, GO:0005667=IDA, GO:0001569=IEA, GO:0006355=IDA, GO:0060412=IEA, GO:0021855=IEA, GO:0003677=IEA, GO:0043565=IEA, GO:0060460=IEA, GO:0008585=IEA, GO:0001077=IEA, GO:0021763=IEA, GO:0048557=IEA, GO:0035116=IEA, GO:0003253=ISS, GO:0001764=IEA, GO:0001570=IEA, GO:0008584=IEA, GO:0061031=IEA} Wnt receptor signaling pathway, atrial cardiac muscle tissue morphogenesis, atrioventricular valve development, camera-type eye development, cardiac neural crest cell migration involved in outflow tract morphogenesis, cell proliferation involved in outflow tract morphogenesis, deltoid tuberosity development, determination of left/right symmetry, embryonic camera-type eye development, embryonic digestive tract morphogenesis, embryonic hindlimb morphogenesis, endodermal digestive tract morphogenesis, extraocular skeletal muscle development, female gonad development, hair cell differentiation, hypothalamus cell migration, in utero embryonic development, iris morphogenesis, left lung morphogenesis, left/right axis specification, male gonad development, multicellular organismal development, myoblast fusion, neuron differentiation, neuron migration, odontogenesis, odontogenesis of dentin-containing tooth, patterning of blood vessels, positive regulation of DNA binding, positive regulation of myoblast proliferation, positive regulation of transcription from RNA polymerase II promoter, prolactin secreting cell differentiation, pulmonary myocardium development, pulmonary vein morphogenesis, regulation of cell migration, regulation of transcription, DNA-dependent, response to hormone stimulus, response to vitamin A, somatotropin secreting cell differentiation, spleen development, subthalamic nucleus development, superior vena cava morphogenesis, vascular smooth muscle cell differentiation, vasculogenesis, ventricular cardiac muscle cell development, ventricular septum morphogenesis cytoplasm, nucleus, transcription factor complex DNA binding, RNA polymerase II activating transcription factor binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II transcription coactivator activity, chromatin DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region sequence-specific DNA binding Human UniProtKB:P97474 PITX3 PINC UniProtKB {GO:0006355=GO_REF:0000024, GO:0003700=GO_REF:0000002, GO:0070306=GO_REF:0000019, GO:0005634=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0002089=GO_REF:0000024, GO:0048666=GO_REF:0000019, GO:0002088=GO_REF:0000024, GO:0071542=GO_REF:0000024, GO:0009887=PMID:9620774, GO:0007626=GO_REF:0000019, GO:0030901=GO_REF:0000024, GO:0045893=GO_REF:0000024} O75364 Pituitary homeobox 3 protein 20031120 {GO:0006355=ISS, GO:0003700=IEA, GO:0070306=IEA, GO:0005634=ISS, GO:0006351=IEA, GO:0043565=IEA, GO:0002089=ISS, GO:0048666=IEA, GO:0002088=ISS, GO:0071542=ISS, GO:0009887=TAS, GO:0007626=IEA, GO:0030901=ISS, GO:0045893=ISS} dopaminergic neuron differentiation, lens development in camera-type eye, lens fiber cell differentiation, lens morphogenesis in camera-type eye, locomotory behavior, midbrain development, neuron development, organ morphogenesis, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human PIWIL1 IntAct UniProtKB {GO:0005515=PMID:14749716, GO:0003727=GO_REF:0000019, GO:0007286=GO_REF:0000024, GO:0007275=GO_REF:0000037, GO:0034584=GO_REF:0000024, GO:0031047=GO_REF:0000024, GO:0003729=GO_REF:0000024, GO:0006417=GO_REF:0000037, GO:0033391=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0007126=GO_REF:0000037, GO:0034587=GO_REF:0000019, GO:0043186=GO_REF:0000024, GO:0005844=GO_REF:0000019, GO:0005845=GO_REF:0000019} Q96J94 Piwi-like protein 1 protein 20130415 {GO:0005515=IPI, GO:0003727=IEA, GO:0007286=ISS, GO:0007275=IEA, GO:0034584=ISS, GO:0031047=ISS, GO:0003729=ISS, GO:0006417=IEA, GO:0033391=ISS, GO:0005737=ISS, GO:0007126=IEA, GO:0034587=IEA, GO:0043186=ISS, GO:0005844=IEA, GO:0005845=IEA} gene silencing by RNA, meiosis, multicellular organismal development, piRNA metabolic process, regulation of translation, spermatid development P granule, chromatoid body, cytoplasm, mRNA cap binding complex, polysome mRNA binding, piRNA binding, protein binding, single-stranded RNA binding Human UniProtKB:Q9UPY3 PIWIL2 UniProtKB UniProtKB {GO:0048477=GO_REF:0000024, GO:0000966=GO_REF:0000024, GO:0007275=GO_REF:0000037, GO:0045727=GO_REF:0000024, GO:0031047=GO_REF:0000024, GO:0007283=GO_REF:0000019, GO:0034584=PMID:21193640, GO:0003729=GO_REF:0000019, GO:0007128=GO_REF:0000019, GO:0033391=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0034587=GO_REF:0000024, GO:0071546=GO_REF:0000024, GO:0043186=GO_REF:0000024, GO:0005844=GO_REF:0000019, GO:0030718=GO_REF:0000024, GO:0043046=GO_REF:0000024} Q8TC59 Piwi-like protein 2 protein 20110211 {GO:0048477=ISS, GO:0000966=ISS, GO:0007275=IEA, GO:0045727=ISS, GO:0031047=ISS, GO:0007283=IEA, GO:0034584=IDA, GO:0003729=IEA, GO:0007128=IEA, GO:0033391=ISS, GO:0005737=ISS, GO:0034587=ISS, GO:0071546=ISS, GO:0043186=ISS, GO:0005844=IEA, GO:0030718=ISS, GO:0043046=ISS} DNA methylation involved in gamete generation, RNA 5'-end processing, gene silencing by RNA, germ-line stem cell maintenance, meiotic prophase I, multicellular organismal development, oogenesis, piRNA metabolic process, positive regulation of translation, spermatogenesis P granule, chromatoid body, cytoplasm, pi-body, polysome mRNA binding, piRNA binding Human PIWIL3 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0007126=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0007275=GO_REF:0000037, GO:0031047=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0030154=GO_REF:0000037, GO:0006417=GO_REF:0000037} Q7Z3Z3 Piwi-like protein 3 protein 20130413 {GO:0005737=IEA, GO:0007126=IEA, GO:0003723=IEA, GO:0007275=IEA, GO:0031047=IEA, GO:0007283=IEA, GO:0003676=IEA, GO:0030154=IEA, GO:0006417=IEA} cell differentiation, gene silencing by RNA, meiosis, multicellular organismal development, regulation of translation, spermatogenesis cytoplasm RNA binding, nucleic acid binding Human UniProtKB-SubCell:SL-0086 PIWIL4 UniProtKB UniProtKB {GO:0005634=GO_REF:0000024, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000024, GO:0031047=GO_REF:0000024, GO:0034584=GO_REF:0000024, GO:0003676=GO_REF:0000002, GO:0006417=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0005737=GO_REF:0000024, GO:0007126=GO_REF:0000037, GO:0034587=GO_REF:0000024, GO:0043186=GO_REF:0000024, GO:0071547=GO_REF:0000024, GO:0043046=GO_REF:0000024} Q7Z3Z4 Piwi-like protein 4 protein 20090313 {GO:0005634=ISS, GO:0007275=IEA, GO:0007283=ISS, GO:0031047=ISS, GO:0034584=ISS, GO:0003676=IEA, GO:0006417=IEA, GO:0030154=IEA, GO:0005737=ISS, GO:0007126=IEA, GO:0034587=ISS, GO:0043186=ISS, GO:0071547=ISS, GO:0043046=ISS} DNA methylation involved in gamete generation, cell differentiation, gene silencing by RNA, meiosis, multicellular organismal development, piRNA metabolic process, regulation of translation, spermatogenesis P granule, cytoplasm, nucleus, piP-body nucleic acid binding, piRNA binding Human UniProtKB:Q8CGT6 PJA1 IntAct UniProtKB {GO:0005515=PMID:20864041, GO:0030163=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0004842=GO_REF:0000019, GO:0008270=GO_REF:0000002} Q8NG27 E3 ubiquitin-protein ligase Praja-1 protein 20130415 {GO:0005515=IPI, GO:0030163=IEA, GO:0005737=IEA, GO:0004842=IEA, GO:0008270=IEA} protein catabolic process cytoplasm protein binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q96MG7 PJA2 UniProtKB UniProtKB {GO:0034236=PMID:21423175, GO:0034237=PMID:21423175, GO:0004842=PMID:21423175, GO:0016567=PMID:21423175, GO:0030054=GO_REF:0000037, GO:0005886=PMID:21423175, GO:0007616=GO_REF:0000024, GO:0014069=GO_REF:0000039, GO:0010738=PMID:21423175, GO:0005737=PMID:21423175, GO:0000139=GO_REF:0000039, GO:0045211=GO_REF:0000037, GO:0005789=GO_REF:0000039, GO:0008270=GO_REF:0000002} O43164 E3 ubiquitin-protein ligase Praja-2 protein 20110704 {GO:0034236=IMP, GO:0034237=IMP, GO:0004842=IDA, GO:0016567=IDA, GO:0030054=IEA, GO:0005886=IDA, GO:0007616=ISS, GO:0014069=IEA, GO:0010738=IMP, GO:0005737=IDA, GO:0000139=IEA, GO:0045211=IEA, GO:0005789=IEA, GO:0008270=IEA} long-term memory, protein ubiquitination, regulation of protein kinase A signaling cascade Golgi membrane, cell junction, cytoplasm, endoplasmic reticulum membrane, plasma membrane, postsynaptic density, postsynaptic membrane protein kinase A catalytic subunit binding, protein kinase A regulatory subunit binding, ubiquitin-protein ligase activity, zinc ion binding Human PKD1 GOC UniProtKB {GO:0005515=PMID:20856870, GO:0060674=GO_REF:0000024, GO:0060428=PMID:11891195, GO:0072218=PMID:11891195, GO:0021510=PMID:11891195, GO:0072237=PMID:11891195, GO:0051216=PMID:11891195, GO:0042994=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0009653=PMID:9326937, GO:0032092=GO_REF:0000024, GO:0007507=PMID:11891195, GO:0016323=PMID:10770959, GO:0005737=GO_REF:0000024, GO:0018105=GO_REF:0000024, GO:0050982=GO_REF:0000024, GO:0007218=GO_REF:0000002, GO:0045944=PMID:16311606, GO:0072177=PMID:11891195, GO:0006611=GO_REF:0000024, GO:0007050=GO_REF:0000024, GO:0048806=PMID:11891195, GO:0007156=PMID:10861291, GO:0005262=GO_REF:0000033, GO:0005261=GO_REF:0000024, GO:0019901=PMID:17980165, GO:0001822=GO_REF:0000024, GO:0019904=PMID:9171830, GO:0001892=GO_REF:0000024, GO:0048565=PMID:11891195, GO:0031512=GO_REF:0000024, GO:0002133=GO_REF:0000024, GO:0001701=GO_REF:0000024, GO:0072205=PMID:11891195, GO:0007259=GO_REF:0000024, GO:0044325=PMID:9192675, GO:0005929=GO_REF:0000024, GO:0072287=PMID:11891195, GO:0031659=PMID:16311606, GO:0007160=PMID:7663510, GO:0005887=PMID:7663510, GO:0007161=PMID:10861291, GO:0070588=GO_REF:0000033, GO:0030246=GO_REF:0000002, GO:0043588=PMID:11891195, GO:0048754=PMID:12482949, GO:0016021=PMID:10097141, GO:0072164=PMID:11891195} P98161 Polycystin-1 protein 20130413 {GO:0005515=IPI, GO:0060674=ISS, GO:0060428=IEP, GO:0072218=IEP, GO:0021510=IEP, GO:0072237=IEP, GO:0051216=IEP, GO:0042994=ISS, GO:0005634=ISS, GO:0009653=TAS, GO:0032092=ISS, GO:0007507=IEP, GO:0016323=IDA, GO:0005737=ISS, GO:0018105=ISS, GO:0050982=ISS, GO:0007218=IEA, GO:0045944=IDA, GO:0072177=IEP, GO:0006611=ISS, GO:0007050=ISS, GO:0048806=IEP, GO:0007156=TAS, GO:0005262=IBA, GO:0005261=ISS, GO:0019901=IPI, GO:0001822=ISS, GO:0019904=IPI, GO:0001892=ISS, GO:0048565=IEP, GO:0031512=ISS, GO:0002133=ISS, GO:0001701=ISS, GO:0072205=IEP, GO:0007259=ISS, GO:0044325=IPI, GO:0005929=ISS, GO:0072287=IEP, GO:0031659=IDA, GO:0007160=TAS, GO:0005887=TAS, GO:0007161=TAS, GO:0070588=IBA, GO:0030246=IEA, GO:0043588=IEP, GO:0048754=IDA, GO:0016021=NAS, GO:0072164=IEP} JAK-STAT cascade, anatomical structure morphogenesis, branching morphogenesis of an epithelial tube, calcium ion transmembrane transport, calcium-independent cell-matrix adhesion, cartilage development, cell cycle arrest, cell-matrix adhesion, cytoplasmic sequestering of transcription factor, detection of mechanical stimulus, digestive tract development, embryonic placenta development, genitalia development, heart development, homophilic cell adhesion, in utero embryonic development, kidney development, lung epithelium development, mesonephric duct development, mesonephric tubule development, metanephric ascending thin limb development, metanephric collecting duct development, metanephric distal tubule morphogenesis, metanephric proximal tubule development, neuropeptide signaling pathway, peptidyl-serine phosphorylation, placenta blood vessel development, positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S, positive regulation of protein binding, positive regulation of transcription from RNA polymerase II promoter, protein export from nucleus, skin development, spinal cord development basolateral plasma membrane, cilium, cytoplasm, integral to membrane, integral to plasma membrane, motile primary cilium, nucleus, polycystin complex calcium channel activity, carbohydrate binding, cation channel activity, ion channel binding, protein binding, protein domain specific binding, protein kinase binding Human PANTHER:PTN000093539 PKD1L2 UniProtKB UniProtKB {GO:0007218=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0030246=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0006811=GO_REF:0000037} Q7Z442 Polycystic kidney disease protein 1-like 2 protein 20130413 {GO:0007218=IEA, GO:0005509=IEA, GO:0030246=IEA, GO:0016021=IEA, GO:0006811=IEA} ion transport, neuropeptide signaling pathway integral to membrane calcium ion binding, carbohydrate binding Human UniProtKB-KW:KW-0812 PKD1L3 BHF-UCL UniProtKB {GO:0005261=GO_REF:0000024, GO:0009986=GO_REF:0000024, GO:0007218=GO_REF:0000002, GO:0008324=GO_REF:0000024, GO:0030246=GO_REF:0000002, GO:0033040=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0071468=GO_REF:0000024, GO:0006812=GO_REF:0000024, GO:0001581=GO_REF:0000024} Q7Z443 Polycystic kidney disease protein 1-like 3 protein 20120119 {GO:0005261=ISS, GO:0009986=ISS, GO:0007218=IEA, GO:0008324=ISS, GO:0030246=IEA, GO:0033040=ISS, GO:0016021=IEA, GO:0071468=ISS, GO:0006812=ISS, GO:0001581=ISS} cation transport, cellular response to acidity, detection of chemical stimulus involved in sensory perception of sour taste, neuropeptide signaling pathway cell surface, integral to membrane carbohydrate binding, cation channel activity, cation transmembrane transporter activity, sour taste receptor activity Human UniProtKB:Q2EG98 PKD2 BHF-UCL UniProtKB {GO:0008092=PMID:10760273, GO:0005515=PMID:10760273, GO:0072686=PMID:15123714, GO:0001658=PMID:11891195, GO:0060674=GO_REF:0000024, GO:0042805=PMID:15843396, GO:0042994=PMID:16311606, GO:0072235=PMID:11891195, GO:0071158=PMID:16311606, GO:0042803=PMID:9192675, GO:0042802=GO_REF:0000024, GO:0072075=PMID:11891195, GO:0001947=PMID:21719175, GO:0007507=PMID:11891195, GO:0061333=GO_REF:0000024, GO:0009925=PMID:10770959, GO:0050982=GO_REF:0000024, GO:0043398=PMID:16311606, GO:0042127=PMID:15001556, GO:0072177=PMID:11891195, GO:0051117=GO_REF:0000024, GO:0005932=PMID:15337773, GO:0051209=PMID:19265036, GO:0031587=PMID:16223735, GO:0005509=GO_REF:0000024, GO:0005267=GO_REF:0000024, GO:0001892=GO_REF:0000024, GO:0003127=GO_REF:0000024, GO:2000134=PMID:16311606, GO:0072208=PMID:11891195, GO:0002133=GO_REF:0000024, GO:0030027=PMID:10760273, GO:0044325=PMID:10097141, GO:0001889=PMID:11891195, GO:0005929=GO_REF:0000024, GO:0072284=PMID:11891195, GO:0005887=PMID:21044049, GO:0070588=PMID:11854751, GO:0005789=PMID:11854751, GO:0072214=PMID:11891195, GO:0007368=GO_REF:0000024, GO:0008285=PMID:18664456, GO:0045180=PMID:10770959, GO:0005886=PMID:15692563, GO:0072218=PMID:11891195, GO:0021510=PMID:11891195, GO:0005783=PMID:10760273, GO:0072219=PMID:11891195, GO:0045429=PMID:19265036, GO:0044441=GO_REF:0000019, GO:0005737=PMID:10770959, GO:0005911=GO_REF:0000024, GO:0045944=PMID:16311606, GO:0060315=GO_REF:0000024, GO:0071556=PMID:21044049, GO:0007050=GO_REF:0000024, GO:0035725=PMID:11252306, GO:0006816=GO_REF:0000024, GO:0030814=GO_REF:0000024, GO:0005244=PMID:11854751, GO:0048763=PMID:11854751, GO:0005245=PMID:15692563, GO:0071910=PMID:21719175, GO:0090279=PMID:11854751, GO:0001822=GO_REF:0000019, GO:0005248=PMID:11252306, GO:0035502=PMID:11891195, GO:0061441=PMID:11891195, GO:0005102=PMID:16223735, GO:0031513=GO_REF:0000024, GO:0071458=PMID:21044049, GO:0031512=GO_REF:0000024, GO:0007259=GO_REF:0000024, GO:0071498=PMID:19265036, GO:0035904=PMID:11891195, GO:0010628=GO_REF:0000019, GO:0051298=PMID:18725310, GO:0031659=PMID:16311606, GO:0034614=PMID:18417208, GO:0021915=PMID:11891195, GO:0072164=PMID:11891195} Q13563 Polycystin-2 protein 20110112 {GO:0008092=IDA, GO:0005515=IPI, GO:0072686=IDA, GO:0001658=IEP, GO:0060674=ISS, GO:0042805=IDA, GO:0042994=IMP, GO:0072235=IEP, GO:0071158=IMP, GO:0042803=IDA, GO:0042802=ISS, GO:0072075=IEP, GO:0001947=IMP, GO:0007507=IEP, GO:0061333=ISS, GO:0009925=IDA, GO:0050982=ISS, GO:0043398=IPI, GO:0042127=IMP, GO:0072177=IEP, GO:0051117=ISS, GO:0005932=IDA, GO:0051209=IMP, GO:0031587=IMP, GO:0005509=ISS, GO:0005267=ISS, GO:0001892=ISS, GO:0003127=ISS, GO:2000134=IMP, GO:0072208=IEP, GO:0002133=ISS, GO:0030027=IDA, GO:0044325=IPI, GO:0001889=IEP, GO:0005929=ISS, GO:0072284=IEP, GO:0005887=IDA, GO:0070588=IDA, GO:0005789=IDA, GO:0072214=IEP, GO:0007368=ISS, GO:0008285=NAS, GO:0045180=IDA, GO:0005886=IDA, GO:0072218=IEP, GO:0021510=IEP, GO:0005783=IDA, GO:0072219=IEP, GO:0045429=IMP, GO:0044441=IEA, GO:0005737=IDA, GO:0005911=ISS, GO:0045944=IDA, GO:0060315=ISS, GO:0071556=IDA, GO:0007050=ISS, GO:0035725=IDA, GO:0006816=ISS, GO:0030814=ISS, GO:0005244=IDA, GO:0048763=IDA, GO:0005245=IDA, GO:0071910=IMP, GO:0090279=IDA, GO:0001822=IEA, GO:0005248=IDA, GO:0035502=IEP, GO:0061441=IEP, GO:0005102=IPI, GO:0031513=ISS, GO:0071458=IDA, GO:0031512=ISS, GO:0007259=ISS, GO:0071498=IMP, GO:0035904=IEP, GO:0010628=IEA, GO:0051298=NAS, GO:0031659=IDA, GO:0034614=NAS, GO:0021915=IEP, GO:0072164=IEP} JAK-STAT cascade, aorta development, branching involved in ureteric bud morphogenesis, calcium ion transmembrane transport, calcium ion transport, cell cycle arrest, cellular response to fluid shear stress, cellular response to reactive oxygen species, centrosome duplication, cytoplasmic sequestering of transcription factor, detection of mechanical stimulus, detection of nodal flow, determination of left/right symmetry, determination of liver left/right asymmetry, embryonic placenta development, heart development, heart looping, kidney development, liver development, mesonephric duct development, mesonephric tubule development, metanephric S-shaped body morphogenesis, metanephric ascending thin limb development, metanephric cortex development, metanephric cortical collecting duct development, metanephric distal tubule development, metanephric mesenchyme development, metanephric part of ureteric bud development, metanephric smooth muscle tissue development, negative regulation of G1/S transition of mitotic cell cycle, negative regulation of cell proliferation, negative regulation of ryanodine-sensitive calcium-release channel activity, neural tube development, placenta blood vessel development, positive regulation of cell cycle arrest, positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S, positive regulation of gene expression, positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity, positive regulation of nitric oxide biosynthetic process, positive regulation of transcription from RNA polymerase II promoter, regulation of cAMP metabolic process, regulation of calcium ion import, regulation of cell proliferation, release of sequestered calcium ion into cytosol, renal artery morphogenesis, renal tubule morphogenesis, sodium ion transmembrane transport, spinal cord development basal cortex, basal plasma membrane, cell-cell junction, cilium, cilium part, cytoplasm, endoplasmic reticulum, endoplasmic reticulum membrane, integral to cytosolic side of endoplasmic reticulum membrane, integral to lumenal side of endoplasmic reticulum membrane, integral to plasma membrane, lamellipodium, microtubule basal body, mitotic spindle, motile primary cilium, nonmotile primary cilium, plasma membrane, polycystin complex ATPase binding, HLH domain binding, actinin binding, calcium ion binding, calcium-induced calcium release activity, cytoskeletal protein binding, identical protein binding, ion channel binding, potassium channel activity, protein binding, protein homodimerization activity, receptor binding, voltage-gated calcium channel activity, voltage-gated ion channel activity, voltage-gated sodium channel activity Human PKD2L1 GOC UniProtKB {GO:0005515=PMID:12525172, GO:0008092=PMID:12809519, GO:0005886=PMID:17944866, GO:0005272=PMID:10517637, GO:0005783=GO_REF:0000024, GO:0008324=GO_REF:0000024, GO:0071468=GO_REF:0000024, GO:0042802=GO_REF:0000024, GO:0043231=PMID:17944866, GO:0050982=GO_REF:0000033, GO:0035725=PMID:10517637, GO:0005227=PMID:11959145, GO:0006812=GO_REF:0000024, GO:0071805=PMID:10517637, GO:0001581=GO_REF:0000024, GO:0005262=GO_REF:0000033, GO:0005261=PMID:17944866, GO:0009986=GO_REF:0000024, GO:0005509=GO_REF:0000024, GO:0051371=PMID:17944866, GO:0051393=PMID:17944866, GO:0070588=GO_REF:0000033, GO:0016021=PMID:9748274, GO:0033040=GO_REF:0000024, GO:0015269=PMID:10517637} Q9P0L9 Polycystic kidney disease 2-like 1 protein protein 20130413 {GO:0005515=IPI, GO:0008092=IPI, GO:0005886=IMP, GO:0005272=IDA, GO:0005783=ISS, GO:0008324=ISS, GO:0071468=ISS, GO:0042802=ISS, GO:0043231=IDA, GO:0050982=IBA, GO:0035725=IDA, GO:0005227=IDA, GO:0006812=ISS, GO:0071805=IDA, GO:0001581=ISS, GO:0005262=IBA, GO:0005261=IDA, GO:0009986=ISS, GO:0005509=ISS, GO:0051371=IPI, GO:0051393=IPI, GO:0070588=IBA, GO:0016021=NAS, GO:0033040=ISS, GO:0015269=IDA} calcium ion transmembrane transport, cation transport, cellular response to acidity, detection of chemical stimulus involved in sensory perception of sour taste, detection of mechanical stimulus, potassium ion transmembrane transport, sodium ion transmembrane transport cell surface, endoplasmic reticulum, integral to membrane, intracellular membrane-bounded organelle, plasma membrane alpha-actinin binding, calcium activated cation channel activity, calcium channel activity, calcium ion binding, calcium-activated potassium channel activity, cation channel activity, cation transmembrane transporter activity, cytoskeletal protein binding, identical protein binding, muscle alpha-actinin binding, protein binding, sodium channel activity, sour taste receptor activity Human PANTHER:PTN000093539 PKDREJ GOC UniProtKB {GO:0005262=GO_REF:0000033, GO:0060046=GO_REF:0000019, GO:0016020=PMID:9949214, GO:0050982=GO_REF:0000033, GO:0005886=GO_REF:0000019, GO:0007218=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0070588=GO_REF:0000033, GO:0007340=PMID:9949214, GO:0016021=GO_REF:0000037} Q9NTG1 Polycystic kidney disease and receptor for egg jelly-related protein protein 20130413 {GO:0005262=IBA, GO:0060046=IEA, GO:0016020=TAS, GO:0050982=IBA, GO:0005886=IEA, GO:0007218=IEA, GO:0005509=IEA, GO:0070588=IBA, GO:0007340=TAS, GO:0016021=IEA} acrosome reaction, calcium ion transmembrane transport, detection of mechanical stimulus, neuropeptide signaling pathway, regulation of acrosome reaction integral to membrane, membrane, plasma membrane calcium channel activity, calcium ion binding Human PANTHER:PTN000093539 PKHD1 UniProtKB UniProtKB {GO:0005515=PMID:16243292, GO:0072686=PMID:20554582, GO:0005813=PMID:20554582, GO:0001822=GO_REF:0000024, GO:0042592=PMID:11919560, GO:0010824=PMID:20554582, GO:0072372=PMID:115458427, GO:0031362=PMID:11919560, GO:0042384=GO_REF:0000024, GO:0005737=GO_REF:0000037, GO:0016324=PMID:16243292, GO:0016337=GO_REF:0000024, GO:0004872=PMID:11919560, GO:0016021=GO_REF:0000037, GO:0005932=PMID:14978161, GO:0051271=GO_REF:0000024} P08F94 Fibrocystin protein 20111005 {GO:0005515=IPI, GO:0072686=IDA, GO:0005813=IDA, GO:0001822=ISS, GO:0042592=NAS, GO:0010824=IMP, GO:0072372=IDA, GO:0031362=TAS, GO:0042384=ISS, GO:0005737=IEA, GO:0016324=IDA, GO:0016337=ISS, GO:0004872=NAS, GO:0016021=IEA, GO:0005932=IDA, GO:0051271=ISS} cell-cell adhesion, cilium assembly, homeostatic process, kidney development, negative regulation of cellular component movement, regulation of centrosome duplication anchored to external side of plasma membrane, apical plasma membrane, centrosome, cytoplasm, integral to membrane, microtubule basal body, mitotic spindle, primary cilium protein binding, receptor activity Human PKIA UniProtKB UniProtKB {GO:0005737=GO_REF:0000019, GO:0010389=GO_REF:0000019, GO:0042308=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0004862=PMID:1710219, GO:0000122=GO_REF:0000019} P61925 cAMP-dependent protein kinase inhibitor alpha protein 20061108 {GO:0005737=IEA, GO:0010389=IEA, GO:0042308=IEA, GO:0005634=IEA, GO:0004862=TAS, GO:0000122=IEA} negative regulation of protein import into nucleus, negative regulation of transcription from RNA polymerase II promoter, regulation of G2/M transition of mitotic cell cycle cytoplasm, nucleus cAMP-dependent protein kinase inhibitor activity Human PKIB InterPro UniProtKB {GO:0004862=GO_REF:0000002} Q9C010 cAMP-dependent protein kinase inhibitor beta protein 20130413 {GO:0004862=IEA} cAMP-dependent protein kinase inhibitor activity Human InterPro:IPR004171 PKIG ENSEMBL UniProtKB {GO:0007165=GO_REF:0000019, GO:0042308=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0004862=GO_REF:0000019} Q9Y2B9 cAMP-dependent protein kinase inhibitor gamma protein 20130413 {GO:0007165=IEA, GO:0042308=IEA, GO:0000122=IEA, GO:0004862=IEA} negative regulation of protein import into nucleus, negative regulation of transcription from RNA polymerase II promoter, signal transduction cAMP-dependent protein kinase inhibitor activity Human Ensembl:ENSMUSP00000105027 PKLR Reactome UniProtKB {GO:0001666=GO_REF:0000019, GO:0032869=GO_REF:0000019, GO:0000287=GO_REF:0000002, GO:0009408=GO_REF:0000019, GO:0005975=Reactome:REACT_474, GO:0007584=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0030955=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0051591=GO_REF:0000019, GO:0006096=Reactome:REACT_1383, GO:0005829=Reactome:REACT_1524, GO:0009749=GO_REF:0000019, GO:0006754=GO_REF:0000019, GO:0031325=Reactome:REACT_2122, GO:0006112=Reactome:REACT_1505, GO:0010226=GO_REF:0000019, GO:0031018=Reactome:REACT_13819, GO:0006006=Reactome:REACT_723, GO:0033198=GO_REF:0000019, GO:0042866=GO_REF:0000019, GO:0004743=GO_REF:0000003, GO:0051707=GO_REF:0000019} P30613 Pyruvate kinase isozymes R/L protein 20130301 {GO:0001666=IEA, GO:0032869=IEA, GO:0000287=IEA, GO:0009408=IEA, GO:0005975=TAS, GO:0007584=IEA, GO:0044281=TAS, GO:0030955=IEA, GO:0005524=IEA, GO:0051591=IEA, GO:0006096=TAS, GO:0005829=TAS, GO:0009749=IEA, GO:0006754=IEA, GO:0031325=TAS, GO:0006112=TAS, GO:0010226=IEA, GO:0031018=TAS, GO:0006006=TAS, GO:0033198=IEA, GO:0042866=IEA, GO:0004743=IEA, GO:0051707=IEA} ATP biosynthetic process, carbohydrate metabolic process, cellular response to insulin stimulus, endocrine pancreas development, energy reserve metabolic process, glucose metabolic process, glycolysis, positive regulation of cellular metabolic process, pyruvate biosynthetic process, response to ATP, response to cAMP, response to glucose stimulus, response to heat, response to hypoxia, response to lithium ion, response to nutrient, response to other organism, small molecule metabolic process cytosol ATP binding, magnesium ion binding, potassium ion binding, pyruvate kinase activity Human PKMYT1 IntAct UniProtKB {GO:0005515=PMID:10373560, GO:0007088=PMID:9001210, GO:0005794=PMID:9001210, GO:0005783=PMID:9001210, GO:0005634=GO_REF:0000019, GO:0000079=PMID:9001210, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0000082=Reactome:REACT_1783, GO:0007067=PMID:9001210, GO:0005737=GO_REF:0000019, GO:0007049=GO_REF:0000002, GO:0004672=PMID:9001210, GO:0016020=PMID:9001210, GO:0000139=GO_REF:0000039, GO:0016301=PMID:9268380, GO:0004674=GO_REF:0000037, GO:0000086=Reactome:REACT_2203, GO:0010923=PMID:19389623, GO:0051726=Reactome:REACT_1006, GO:0005789=GO_REF:0000039, GO:0005654=Reactome:REACT_1657, GO:0000278=Reactome:REACT_152} Q99640 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase protein 20130415 {GO:0005515=IPI, GO:0007088=TAS, GO:0005794=TAS, GO:0005783=TAS, GO:0005634=IEA, GO:0000079=TAS, GO:0005524=IEA, GO:0046872=IEA, GO:0000082=TAS, GO:0007067=TAS, GO:0005737=IEA, GO:0007049=IEA, GO:0004672=TAS, GO:0016020=TAS, GO:0000139=IEA, GO:0016301=IDA, GO:0004674=IEA, GO:0000086=TAS, GO:0010923=IDA, GO:0051726=TAS, GO:0005789=IEA, GO:0005654=TAS, GO:0000278=TAS} G1/S transition of mitotic cell cycle, G2/M transition of mitotic cell cycle, cell cycle, mitosis, mitotic cell cycle, negative regulation of phosphatase activity, regulation of cell cycle, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of mitosis Golgi apparatus, Golgi membrane, cytoplasm, endoplasmic reticulum, endoplasmic reticulum membrane, membrane, nucleoplasm, nucleus ATP binding, kinase activity, metal ion binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB:P14635 PKN1 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0005886=GO_REF:0000039, GO:0042826=PMID:20188095, GO:2000145=PMID:21754995, GO:0005634=PMID:12514133, GO:0050681=PMID:12514133, GO:0032154=PMID:17332740, GO:0042393=PMID:18066052, GO:0005737=PMID:17332740, GO:0030374=PMID:12514133, GO:0005080=PMID:20228790, GO:0006357=PMID:12514133, GO:0030496=PMID:17332740, GO:0007257=PMID:8805275, GO:0035407=PMID:18066052, GO:0006972=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0035402=PMID:18066052, GO:0007165=PMID:8135837, GO:0048365=PMID:18006505, GO:0004672=PMID:10792047, GO:0004674=PMID:20188095, GO:0003682=PMID:18066052, GO:0010631=PMID:21754995, GO:0016023=GO_REF:0000019, GO:0006468=PMID:17332740, GO:0017049=PMID:10619026, GO:0004697=GO_REF:0000003, GO:0005768=PMID:9478917} Q16512 Serine/threonine-protein kinase N1 protein 20130415 {GO:0005515=IPI, GO:0005886=IEA, GO:0042826=IDA, GO:2000145=IMP, GO:0005634=IDA, GO:0050681=IDA, GO:0032154=IDA, GO:0042393=IDA, GO:0005737=IDA, GO:0030374=IDA, GO:0005080=IPI, GO:0006357=IDA, GO:0030496=IDA, GO:0007257=TAS, GO:0035407=IDA, GO:0006972=IEA, GO:0005524=IEA, GO:0006351=IEA, GO:0035402=IDA, GO:0007165=TAS, GO:0048365=IDA, GO:0004672=TAS, GO:0004674=IDA, GO:0003682=IDA, GO:0010631=IMP, GO:0016023=IEA, GO:0006468=IDA, GO:0017049=IDA, GO:0004697=IEA, GO:0005768=IDA} activation of JUN kinase activity, epithelial cell migration, histone H3-T11 phosphorylation, hyperosmotic response, protein phosphorylation, regulation of cell motility, regulation of transcription from RNA polymerase II promoter, signal transduction, transcription, DNA-dependent cleavage furrow, cytoplasm, cytoplasmic membrane-bounded vesicle, endosome, midbody, nucleus, plasma membrane ATP binding, GTP-Rho binding, Rac GTPase binding, androgen receptor binding, chromatin binding, histone binding, histone deacetylase binding, histone kinase activity (H3-T11 specific), ligand-dependent nuclear receptor transcription coactivator activity, protein binding, protein kinase C activity, protein kinase C binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB:Q15834 PKN2 PINC UniProtKB {GO:0005515=PMID:10026169, GO:0042826=PMID:20188095, GO:2000145=PMID:21754995, GO:0005634=PMID:11356191, GO:0032154=PMID:17332740, GO:0043297=PMID:20974804, GO:0043296=PMID:20974804, GO:0005737=PMID:17332740, GO:0016301=GO_REF:0000038, GO:0005856=GO_REF:0000039, GO:0007155=GO_REF:0000037, GO:0006355=GO_REF:0000037, GO:0006915=GO_REF:0000037, GO:0030496=PMID:17332740, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0030027=PMID:11356191, GO:0007165=GO_REF:0000002, GO:0045931=PMID:17332740, GO:0007049=GO_REF:0000037, GO:0004672=PMID:7851406, GO:0016020=GO_REF:0000039, GO:0004674=PMID:20188095, GO:0010631=PMID:21754995, GO:0006468=PMID:17332740, GO:0004697=GO_REF:0000003, GO:0051301=GO_REF:0000037} Q16513 Serine/threonine-protein kinase N2 protein 20030904 {GO:0005515=IPI, GO:0042826=IDA, GO:2000145=IMP, GO:0005634=IDA, GO:0032154=IDA, GO:0043297=IMP, GO:0043296=IDA, GO:0005737=IDA, GO:0016301=IEA, GO:0005856=IEA, GO:0007155=IEA, GO:0006355=IEA, GO:0006915=IEA, GO:0030496=IDA, GO:0005524=IEA, GO:0006351=IEA, GO:0030027=IDA, GO:0007165=IEA, GO:0045931=IMP, GO:0007049=IEA, GO:0004672=TAS, GO:0016020=IEA, GO:0004674=IDA, GO:0010631=IDA, GO:0006468=IDA, GO:0004697=IEA, GO:0051301=IEA} apical junction assembly, apoptotic process, cell adhesion, cell cycle, cell division, epithelial cell migration, positive regulation of mitotic cell cycle, protein phosphorylation, regulation of cell motility, regulation of transcription, DNA-dependent, signal transduction, transcription, DNA-dependent apical junction complex, cleavage furrow, cytoplasm, cytoskeleton, lamellipodium, membrane, midbody, nucleus ATP binding, histone deacetylase binding, kinase activity, protein binding, protein kinase C activity, protein kinase activity, protein serine/threonine kinase activity Human PKN3 IntAct UniProtKB {GO:0005515=PMID:11432776, GO:0007165=GO_REF:0000002, GO:0048471=GO_REF:0000039, GO:0005794=PMID:10441506, GO:0004672=PMID:10441506, GO:0010631=PMID:21754995, GO:0006468=PMID:10441506, GO:0005634=GO_REF:0000039, GO:0004697=GO_REF:0000003, GO:0005524=GO_REF:0000037} Q6P5Z2 Serine/threonine-protein kinase N3 protein 20130415 {GO:0005515=IPI, GO:0007165=IEA, GO:0048471=IEA, GO:0005794=TAS, GO:0004672=TAS, GO:0010631=IDA, GO:0006468=TAS, GO:0005634=IEA, GO:0004697=IEA, GO:0005524=IEA} epithelial cell migration, protein phosphorylation, signal transduction Golgi apparatus, nucleus, perinuclear region of cytoplasm ATP binding, protein binding, protein kinase C activity, protein kinase activity Human UniProtKB:Q9UNA1 PKNOX1 PINC UniProtKB {GO:0005667=GO_REF:0000019, GO:0003700=PMID:9143494, GO:0046982=GO_REF:0000019, GO:0006366=PMID:9479508, GO:0003705=GO_REF:0000019, GO:0005634=GO_REF:0000040, GO:0001525=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0030217=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0030218=GO_REF:0000019, GO:0043010=GO_REF:0000019} P55347 Homeobox protein PKNOX1 protein 20030904 {GO:0005667=IEA, GO:0003700=TAS, GO:0046982=IEA, GO:0006366=TAS, GO:0003705=IEA, GO:0005634=IEA, GO:0001525=IEA, GO:0043565=IEA, GO:0005737=IEA, GO:0030217=IEA, GO:0045944=IEA, GO:0030218=IEA, GO:0043010=IEA} T cell differentiation, angiogenesis, camera-type eye development, erythrocyte differentiation, positive regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter cytoplasm, nucleus, transcription factor complex RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, protein heterodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human PKNOX2 MGI UniProtKB {GO:0043565=GO_REF:0000019, GO:0003785=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0051015=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0006357=GO_REF:0000019, GO:0015630=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0015629=GO_REF:0000019, GO:0003677=PMID:12412021} Q96KN3 Homeobox protein PKNOX2 protein 20021206 {GO:0043565=IEA, GO:0003785=IEA, GO:0005737=IEA, GO:0051015=IEA, GO:0003700=IEA, GO:0006357=IEA, GO:0015630=IEA, GO:0005634=IEA, GO:0015629=IEA, GO:0003677=IDA} regulation of transcription from RNA polymerase II promoter actin cytoskeleton, cytoplasm, microtubule cytoskeleton, nucleus DNA binding, actin filament binding, actin monomer binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human PKP1 BHF-UCL UniProtKB {GO:0005515=PMID:10852826, GO:0030057=PMID:7527055, GO:0005882=PMID:7527055, GO:0005886=Reactome:REACT_13418, GO:0005730=GO_REF:0000052, GO:0006915=Reactome:REACT_578, GO:0007275=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0030280=PMID:7527055, GO:0019215=PMID:10852826, GO:0006921=Reactome:REACT_995, GO:0007165=PMID:7527055, GO:0045110=PMID:10852826, GO:0004871=PMID:9326952, GO:0007155=PMID:10852826, GO:0005521=PMID:10852826} Q13835 Plakophilin-1 protein 20120928 {GO:0005515=IPI, GO:0030057=NAS, GO:0005882=TAS, GO:0005886=TAS, GO:0005730=IDA, GO:0006915=TAS, GO:0007275=IEA, GO:0005634=IDA, GO:0030280=NAS, GO:0019215=NAS, GO:0006921=TAS, GO:0007165=NAS, GO:0045110=IDA, GO:0004871=TAS, GO:0007155=NAS, GO:0005521=IDA} apoptotic process, cell adhesion, cellular component disassembly involved in execution phase of apoptosis, intermediate filament bundle assembly, multicellular organismal development, signal transduction desmosome, intermediate filament, nucleolus, nucleus, plasma membrane intermediate filament binding, lamin binding, protein binding, signal transducer activity, structural constituent of epidermis Human UniProtKB:P15924 PKP2 BHF-UCL UniProtKB {GO:0005515=PMID:10852826, GO:0005882=GO_REF:0000024, GO:0030057=GO_REF:0000024, GO:0008285=GO_REF:0000024, GO:2000810=GO_REF:0000024, GO:0005886=PMID:8922383, GO:0055010=PMID:22889254, GO:0034334=GO_REF:0000024, GO:0005634=PMID:8922383, GO:0016264=GO_REF:0000024, GO:0086091=PMID:22781308, GO:0048496=PMID:22889254, GO:0007507=GO_REF:0000024, GO:0003674=GO_REF:0000015, GO:0016337=GO_REF:0000024, GO:0086069=PMID:22781308, GO:0014704=GO_REF:0000024, GO:0005912=GO_REF:0000024, GO:0010765=GO_REF:0000024, GO:0005911=GO_REF:0000024, GO:0005080=PMID:18474624, GO:0045110=PMID:18474624, GO:0086002=PMID:22889254, GO:0002159=PMID:18474624, GO:0086001=GO_REF:0000024, GO:0086005=PMID:22781308, GO:0030336=GO_REF:0000024, GO:0055088=GO_REF:0000024, GO:0086064=GO_REF:0000024, GO:0019215=PMID:10852826, GO:0044325=GO_REF:0000024, GO:0032947=PMID:18474624, GO:0086019=PMID:22889254, GO:0016021=PMID:8922383, GO:0017080=GO_REF:0000024} Q99959 Plakophilin-2 protein 20120928 {GO:0005515=IPI, GO:0005882=ISS, GO:0030057=ISS, GO:0008285=ISS, GO:2000810=ISS, GO:0005886=TAS, GO:0055010=IMP, GO:0034334=ISS, GO:0005634=NAS, GO:0016264=ISS, GO:0086091=IMP, GO:0048496=IMP, GO:0007507=ISS, GO:0003674=ND, GO:0016337=ISS, GO:0086069=IMP, GO:0014704=ISS, GO:0005912=ISS, GO:0010765=ISS, GO:0005911=ISS, GO:0005080=IPI, GO:0045110=IMP, GO:0086002=IMP, GO:0002159=IMP, GO:0086001=ISS, GO:0086005=IMP, GO:0030336=ISS, GO:0055088=ISS, GO:0086064=ISS, GO:0019215=IDA, GO:0044325=ISS, GO:0032947=IMP, GO:0086019=IMP, GO:0016021=TAS, GO:0017080=ISS} adherens junction maintenance, bundle of His cell to Purkinje myocyte communication, cell communication by electrical coupling involved in cardiac conduction, cell-cell adhesion, cell-cell signaling involved in cardiac conduction, desmosome assembly, gap junction assembly, heart development, intermediate filament bundle assembly, lipid homeostasis, maintenance of organ identity, negative regulation of cell migration, negative regulation of cell proliferation, positive regulation of sodium ion transport, regulation of cardiac muscle cell action potential, regulation of cardiac muscle cell action potential involved in contraction, regulation of heart rate by cardiac conduction, regulation of tight junction assembly, regulation of ventricular cardiac muscle cell action potential, ventricular cardiac muscle tissue morphogenesis adherens junction, cell-cell junction, desmosome, integral to membrane, intercalated disc, intermediate filament, nucleus, plasma membrane intermediate filament binding, ion channel binding, molecular_function, protein binding, protein complex scaffold, protein kinase C binding, sodium channel regulator activity Human PKP3 PINC UniProtKB {GO:0030057=GO_REF:0000039, GO:0005911=PMID:10374265, GO:0005634=GO_REF:0000039, GO:0007155=GO_REF:0000037} Q9Y446 Plakophilin-3 protein 20030904 {GO:0030057=IEA, GO:0005911=TAS, GO:0005634=IEA, GO:0007155=IEA} cell adhesion cell-cell junction, desmosome, nucleus Human PKP4 UniProtKB UniProtKB {GO:0005515=PMID:22965878, GO:0030057=PMID:8937994, GO:0072686=PMID:17115030, GO:0048471=PMID:8937994, GO:0005886=PMID:8937994, GO:0007267=PMID:8937994, GO:0030496=PMID:17115030, GO:0051233=PMID:17115030, GO:0030155=PMID:8937994, GO:0010628=GO_REF:0000024, GO:0000922=PMID:17115030, GO:0005737=PMID:22965878, GO:0032321=PMID:17115030, GO:0005911=PMID:8937994, GO:0007043=GO_REF:0000024, GO:0009898=PMID:17115030, GO:0005856=PMID:8937994, GO:0007155=GO_REF:0000037} Q99569 Plakophilin-4 protein 20130129 {GO:0005515=IPI, GO:0030057=IDA, GO:0072686=IDA, GO:0048471=IDA, GO:0005886=IDA, GO:0007267=NAS, GO:0030496=IDA, GO:0051233=IDA, GO:0030155=NAS, GO:0010628=ISS, GO:0000922=IDA, GO:0005737=IDA, GO:0032321=IDA, GO:0005911=IDA, GO:0007043=ISS, GO:0009898=IDA, GO:0005856=IDA, GO:0007155=IEA} cell adhesion, cell-cell junction assembly, cell-cell signaling, positive regulation of Rho GTPase activity, positive regulation of gene expression, regulation of cell adhesion cell-cell junction, cytoplasm, cytoskeleton, desmosome, internal side of plasma membrane, midbody, mitotic spindle, perinuclear region of cytoplasm, plasma membrane, spindle midzone, spindle pole protein binding Human UniProtKB:Q68FH0 PLA1A PINC UniProtKB {GO:0016042=GO_REF:0000037, GO:0006629=PMID:10196188, GO:0016787=GO_REF:0000038, GO:0008970=PMID:10196188, GO:0005576=GO_REF:0000039, GO:0006658=PMID:10196188} Q53H76 Phospholipase A1 member A protein 20070906 {GO:0016042=IEA, GO:0006629=TAS, GO:0016787=IEA, GO:0008970=TAS, GO:0005576=IEA, GO:0006658=TAS} lipid catabolic process, lipid metabolic process, phosphatidylserine metabolic process extracellular region hydrolase activity, phosphatidylcholine 1-acylhydrolase activity Human PLA2G10 BHF-UCL UniProtKB {GO:0019369=PMID:18511424, GO:0051977=PMID:15927955, GO:0043030=PMID:18511424, GO:0044281=Reactome:REACT_111217, GO:0043433=PMID:20844270, GO:0007411=PMID:15927955, GO:0004623=GO_REF:0000003, GO:0006654=Reactome:REACT_120906, GO:0042632=PMID:20844270, GO:0010744=PMID:18511424, GO:0036149=Reactome:REACT_120722, GO:0036148=Reactome:REACT_121324, GO:0005509=GO_REF:0000002, GO:0090238=PMID:20844270, GO:0005576=Reactome:REACT_121397, GO:0010884=PMID:18511424, GO:0004620=PMID:20844270, GO:0016042=GO_REF:0000037, GO:0036150=Reactome:REACT_121384, GO:0032270=PMID:18511424, GO:0090370=PMID:20844270, GO:0032308=PMID:18511424, GO:0006644=Reactome:REACT_120870, GO:0036151=Reactome:REACT_120829, GO:0036152=Reactome:REACT_121369, GO:0046474=Reactome:REACT_121401} O15496 Group 10 secretory phospholipase A2 protein 20110504 {GO:0019369=NAS, GO:0051977=IDA, GO:0043030=IMP, GO:0044281=TAS, GO:0043433=IDA, GO:0007411=IDA, GO:0004623=IEA, GO:0006654=TAS, GO:0042632=ISS, GO:0010744=IC, GO:0036149=TAS, GO:0036148=TAS, GO:0005509=IEA, GO:0090238=ISS, GO:0005576=TAS, GO:0010884=IMP, GO:0004620=ISS, GO:0016042=IEA, GO:0036150=TAS, GO:0032270=IMP, GO:0090370=ISS, GO:0032308=IMP, GO:0006644=TAS, GO:0036151=TAS, GO:0036152=TAS, GO:0046474=TAS} arachidonic acid metabolic process, axon guidance, cholesterol homeostasis, glycerophospholipid biosynthetic process, lipid catabolic process, lysophospholipid transport, negative regulation of cholesterol efflux, negative regulation of sequence-specific DNA binding transcription factor activity, phosphatidic acid biosynthetic process, phosphatidylcholine acyl-chain remodeling, phosphatidylethanolamine acyl-chain remodeling, phosphatidylglycerol acyl-chain remodeling, phosphatidylinositol acyl-chain remodeling, phosphatidylserine acyl-chain remodeling, phospholipid metabolic process, positive regulation of arachidonic acid secretion, positive regulation of cellular protein metabolic process, positive regulation of lipid storage, positive regulation of macrophage derived foam cell differentiation, positive regulation of prostaglandin secretion, regulation of macrophage activation, small molecule metabolic process extracellular region calcium ion binding, phospholipase A2 activity, phospholipase activity Human UniProtKB:Q9QXX3 PLA2G12A Reactome UniProtKB {GO:0005794=GO_REF:0000019, GO:0005783=GO_REF:0000019, GO:0036149=Reactome:REACT_120722, GO:0005509=GO_REF:0000002, GO:0036148=Reactome:REACT_121324, GO:0005576=Reactome:REACT_121397, GO:0044281=Reactome:REACT_111217, GO:0016042=GO_REF:0000037, GO:0008150=GO_REF:0000015, GO:0036150=Reactome:REACT_121384, GO:0004623=GO_REF:0000002, GO:0047498=PMID:11031251, GO:0006644=Reactome:REACT_120870, GO:0006654=Reactome:REACT_120906, GO:0036151=Reactome:REACT_120829, GO:0046474=Reactome:REACT_121401, GO:0036152=Reactome:REACT_121369} Q9BZM1 Group XIIA secretory phospholipase A2 protein 20110914 {GO:0005794=IEA, GO:0005783=IEA, GO:0036149=TAS, GO:0005509=IEA, GO:0036148=TAS, GO:0005576=TAS, GO:0044281=TAS, GO:0016042=IEA, GO:0008150=ND, GO:0036150=TAS, GO:0004623=IEA, GO:0047498=NAS, GO:0006644=TAS, GO:0006654=TAS, GO:0036151=TAS, GO:0046474=TAS, GO:0036152=TAS} biological_process, glycerophospholipid biosynthetic process, lipid catabolic process, phosphatidic acid biosynthetic process, phosphatidylcholine acyl-chain remodeling, phosphatidylethanolamine acyl-chain remodeling, phosphatidylglycerol acyl-chain remodeling, phosphatidylinositol acyl-chain remodeling, phosphatidylserine acyl-chain remodeling, phospholipid metabolic process, small molecule metabolic process Golgi apparatus, endoplasmic reticulum, extracellular region calcium ion binding, calcium-dependent phospholipase A2 activity, phospholipase A2 activity Human PLA2G15 PINC UniProtKB {GO:0005739=GO_REF:0000019, GO:0006629=GO_REF:0000002, GO:0008374=GO_REF:0000024, GO:0005543=PMID:10092508, GO:0004622=PMID:10092508, GO:0047499=GO_REF:0000024, GO:0006672=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0046470=GO_REF:0000019, GO:0005764=GO_REF:0000024, GO:0009062=PMID:10092508} Q8NCC3 Group XV phospholipase A2 protein 20050308 {GO:0005739=IEA, GO:0006629=IEA, GO:0008374=ISS, GO:0005543=TAS, GO:0004622=TAS, GO:0047499=ISS, GO:0006672=IEA, GO:0005576=IEA, GO:0046470=IEA, GO:0005764=ISS, GO:0009062=TAS} ceramide metabolic process, fatty acid catabolic process, lipid metabolic process, phosphatidylcholine metabolic process extracellular region, lysosome, mitochondrion O-acyltransferase activity, calcium-independent phospholipase A2 activity, lysophospholipase activity, phospholipid binding Human PLA2G16 Reactome UniProtKB {GO:0048471=GO_REF:0000039, GO:0052739=GO_REF:0000003, GO:0005783=GO_REF:0000019, GO:0036149=Reactome:REACT_120722, GO:0052740=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0008654=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0045786=GO_REF:0000019, GO:0005829=Reactome:REACT_121252, GO:0016042=GO_REF:0000037, GO:0036150=Reactome:REACT_121384, GO:0016020=GO_REF:0000019, GO:0004623=PMID:20100577, GO:0008970=GO_REF:0000003, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0036151=Reactome:REACT_120829, GO:0046474=Reactome:REACT_121401, GO:0036152=Reactome:REACT_121369} P53816 HRAS-like suppressor 3 protein 20130301 {GO:0048471=IEA, GO:0052739=IEA, GO:0005783=IEA, GO:0036149=TAS, GO:0052740=IEA, GO:0044281=TAS, GO:0008654=IEA, GO:0005575=ND, GO:0045786=IEA, GO:0005829=TAS, GO:0016042=IEA, GO:0036150=TAS, GO:0016020=IEA, GO:0004623=IDA, GO:0008970=IEA, GO:0016021=IEA, GO:0006644=TAS, GO:0036151=TAS, GO:0046474=TAS, GO:0036152=TAS} glycerophospholipid biosynthetic process, lipid catabolic process, negative regulation of cell cycle, phosphatidylcholine acyl-chain remodeling, phosphatidylethanolamine acyl-chain remodeling, phosphatidylinositol acyl-chain remodeling, phosphatidylserine acyl-chain remodeling, phospholipid biosynthetic process, phospholipid metabolic process, small molecule metabolic process cellular_component, cytosol, endoplasmic reticulum, integral to membrane, membrane, perinuclear region of cytoplasm 1-acyl-2-lysophosphatidylserine acylhydrolase activity, phosphatidylcholine 1-acylhydrolase activity, phosphatidylserine 1-acylhydrolase activity, phospholipase A2 activity Human PLA2G1B InterPro UniProtKB {GO:0032052=PMID:7060561, GO:0043498=PMID:1918029, GO:0010524=PMID:15528384, GO:0044240=PMID:7060561, GO:0050714=PMID:17981679, GO:0048146=PMID:1918029, GO:0044281=Reactome:REACT_111217, GO:0005615=PMID:7060561, GO:0007243=PMID:15528384, GO:0032431=PMID:17981679, GO:0000187=PMID:15528384, GO:0051092=PMID:15528384, GO:0015758=PMID:1918029, GO:0045944=PMID:15528384, GO:0004623=GO_REF:0000002, GO:0047498=PMID:7060561, GO:0007015=PMID:9886417, GO:0006633=PMID:1918029, GO:0030141=GO_REF:0000019, GO:0006654=Reactome:REACT_120906, GO:0050482=PMID:12423354, GO:0019370=PMID:16005851, GO:0032869=PMID:1918029, GO:0002446=PMID:16005851, GO:0036149=Reactome:REACT_120722, GO:0036148=Reactome:REACT_121324, GO:0005509=GO_REF:0000002, GO:0045740=PMID:1918029, GO:0030593=PMID:16005851, GO:0005102=PMID:1918029, GO:0005576=Reactome:REACT_121397, GO:0032637=PMID:15528384, GO:0016042=GO_REF:0000002, GO:0007165=PMID:9886417, GO:0036150=Reactome:REACT_121384, GO:0050778=PMID:16005851, GO:0046470=PMID:7060561, GO:0006644=Reactome:REACT_120870, GO:0036151=Reactome:REACT_120829, GO:0036152=Reactome:REACT_121369, GO:0046474=Reactome:REACT_121401} Q9BS22 PLA2G1B protein protein 20130413 {GO:0032052=ISS, GO:0043498=IDA, GO:0010524=ISS, GO:0044240=IDA, GO:0050714=TAS, GO:0048146=IC, GO:0044281=TAS, GO:0005615=IDA, GO:0007243=ISS, GO:0032431=TAS, GO:0000187=ISS, GO:0051092=ISS, GO:0015758=ISS, GO:0045944=ISS, GO:0004623=IEA, GO:0047498=IDA, GO:0007015=TAS, GO:0006633=IDA, GO:0030141=IEA, GO:0006654=TAS, GO:0050482=TAS, GO:0019370=ISS, GO:0032869=ISS, GO:0002446=ISS, GO:0036149=TAS, GO:0036148=TAS, GO:0005509=IEA, GO:0045740=IDA, GO:0030593=ISS, GO:0005102=IDA, GO:0005576=TAS, GO:0032637=ISS, GO:0016042=IEA, GO:0007165=TAS, GO:0036150=TAS, GO:0050778=ISS, GO:0046470=IDA, GO:0006644=TAS, GO:0036151=TAS, GO:0036152=TAS, GO:0046474=TAS} actin filament organization, activation of MAPK activity, activation of phospholipase A2 activity, arachidonic acid secretion, cellular response to insulin stimulus, fatty acid biosynthetic process, glucose transport, glycerophospholipid biosynthetic process, interleukin-8 production, intracellular protein kinase cascade, leukotriene biosynthetic process, lipid catabolic process, multicellular organismal lipid catabolic process, neutrophil chemotaxis, neutrophil mediated immunity, phosphatidic acid biosynthetic process, phosphatidylcholine acyl-chain remodeling, phosphatidylcholine metabolic process, phosphatidylethanolamine acyl-chain remodeling, phosphatidylglycerol acyl-chain remodeling, phosphatidylinositol acyl-chain remodeling, phosphatidylserine acyl-chain remodeling, phospholipid metabolic process, positive regulation of DNA replication, positive regulation of NF-kappaB transcription factor activity, positive regulation of calcium ion transport into cytosol, positive regulation of fibroblast proliferation, positive regulation of immune response, positive regulation of protein secretion, positive regulation of transcription from RNA polymerase II promoter, signal transduction, small molecule metabolic process extracellular region, extracellular space, secretory granule bile acid binding, calcium ion binding, calcium-dependent phospholipase A2 activity, cell surface binding, phospholipase A2 activity, receptor binding Human InterPro:IPR001211 PLA2G2A BHF-UCL UniProtKB {GO:0050830=PMID:18827909, GO:0010744=PMID:18827909, GO:0005783=GO_REF:0000054, GO:0036149=Reactome:REACT_120722, GO:0005509=GO_REF:0000002, GO:0036148=Reactome:REACT_121324, GO:0005576=Reactome:REACT_121397, GO:0044281=Reactome:REACT_111217, GO:0005615=PMID:17069818, GO:0016042=GO_REF:0000037, GO:0036150=Reactome:REACT_121384, GO:0005543=PMID:9032461, GO:0034374=PMID:18827909, GO:0050729=PMID:18827909, GO:0047498=PMID:9272153, GO:0004623=PMID:17069818, GO:0005789=Reactome:REACT_121385, GO:0030141=GO_REF:0000019, GO:0006644=PMID:17069818, GO:0006654=Reactome:REACT_120906, GO:0046473=PMID:9032461, GO:0036151=Reactome:REACT_120829, GO:0046474=Reactome:REACT_121401, GO:0036152=Reactome:REACT_121369} P14555 Phospholipase A2, membrane associated protein 20090115 {GO:0050830=TAS, GO:0010744=TAS, GO:0005783=IDA, GO:0036149=TAS, GO:0005509=IEA, GO:0036148=TAS, GO:0005576=TAS, GO:0044281=TAS, GO:0005615=IDA, GO:0016042=IEA, GO:0036150=TAS, GO:0005543=IDA, GO:0034374=TAS, GO:0050729=TAS, GO:0047498=TAS, GO:0004623=IDA, GO:0005789=TAS, GO:0030141=IEA, GO:0006644=IDA, GO:0006654=TAS, GO:0046473=IDA, GO:0036151=TAS, GO:0046474=TAS, GO:0036152=TAS} defense response to Gram-positive bacterium, glycerophospholipid biosynthetic process, lipid catabolic process, low-density lipoprotein particle remodeling, phosphatidic acid biosynthetic process, phosphatidic acid metabolic process, phosphatidylcholine acyl-chain remodeling, phosphatidylethanolamine acyl-chain remodeling, phosphatidylglycerol acyl-chain remodeling, phosphatidylinositol acyl-chain remodeling, phosphatidylserine acyl-chain remodeling, phospholipid metabolic process, positive regulation of inflammatory response, positive regulation of macrophage derived foam cell differentiation, small molecule metabolic process endoplasmic reticulum, endoplasmic reticulum membrane, extracellular region, extracellular space, secretory granule calcium ion binding, calcium-dependent phospholipase A2 activity, phospholipase A2 activity, phospholipid binding Human PLA2G3 Reactome UniProtKB {GO:0005886=GO_REF:0000039, GO:0005814=PMID:20393563, GO:0005509=GO_REF:0000002, GO:0036148=Reactome:REACT_121324, GO:0005576=Reactome:REACT_121220, GO:0044281=Reactome:REACT_111217, GO:0005615=PMID:10713052, GO:0016042=GO_REF:0000037, GO:0060271=PMID:20393563, GO:0047498=PMID:10713052, GO:0006644=Reactome:REACT_120870, GO:0036151=Reactome:REACT_120829, GO:0046474=Reactome:REACT_121401, GO:0036152=Reactome:REACT_121369} Q9NZ20 Group 3 secretory phospholipase A2 protein 20110914 {GO:0005886=IEA, GO:0005814=IDA, GO:0005509=IEA, GO:0036148=TAS, GO:0005576=TAS, GO:0044281=TAS, GO:0005615=TAS, GO:0016042=IEA, GO:0060271=IMP, GO:0047498=TAS, GO:0006644=TAS, GO:0036151=TAS, GO:0046474=TAS, GO:0036152=TAS} cilium morphogenesis, glycerophospholipid biosynthetic process, lipid catabolic process, phosphatidylcholine acyl-chain remodeling, phosphatidylethanolamine acyl-chain remodeling, phosphatidylglycerol acyl-chain remodeling, phospholipid metabolic process, small molecule metabolic process centriole, extracellular region, extracellular space, plasma membrane calcium ion binding, calcium-dependent phospholipase A2 activity Human PLA2G4A Reactome UniProtKB {GO:0046456=GO_REF:0000019, GO:0019369=Reactome:REACT_147851, GO:0005743=Reactome:REACT_121167, GO:0035965=Reactome:REACT_121006, GO:0044281=Reactome:REACT_111217, GO:0006690=PMID:9430701, GO:0005829=Reactome:REACT_121405, GO:0005544=PMID:9665851, GO:0042127=GO_REF:0000019, GO:0004622=GO_REF:0000003, GO:0047498=Reactome:REACT_15331, GO:0004623=Reactome:REACT_121167, GO:0006654=Reactome:REACT_120906, GO:0071236=GO_REF:0000019, GO:0050482=GO_REF:0000019, GO:0005794=GO_REF:0000019, GO:0006663=PMID:9430701, GO:0036149=Reactome:REACT_120722, GO:0005509=PMID:9665851, GO:0036148=Reactome:REACT_121324, GO:0030168=Reactome:REACT_798, GO:0004620=GO_REF:0000002, GO:0036150=Reactome:REACT_121384, GO:0007596=Reactome:REACT_604, GO:0005789=Reactome:REACT_23990, GO:0016023=GO_REF:0000039, GO:0006644=Reactome:REACT_120977, GO:0009395=GO_REF:0000002, GO:0036151=Reactome:REACT_120829, GO:0046474=Reactome:REACT_121401, GO:0036152=Reactome:REACT_121369} P47712 Cytosolic phospholipase A2 protein 20120605 {GO:0046456=IEA, GO:0019369=TAS, GO:0005743=TAS, GO:0035965=TAS, GO:0044281=TAS, GO:0006690=NAS, GO:0005829=TAS, GO:0005544=IDA, GO:0042127=IEA, GO:0004622=IEA, GO:0047498=EXP, GO:0004623=TAS, GO:0006654=TAS, GO:0071236=IEA, GO:0050482=IEA, GO:0005794=IEA, GO:0006663=NAS, GO:0036149=TAS, GO:0005509=IDA, GO:0036148=TAS, GO:0030168=TAS, GO:0004620=IEA, GO:0036150=TAS, GO:0007596=TAS, GO:0005789=TAS, GO:0016023=IEA, GO:0006644=TAS, GO:0009395=IEA, GO:0036151=TAS, GO:0046474=TAS, GO:0036152=TAS} arachidonic acid metabolic process, arachidonic acid secretion, blood coagulation, cardiolipin acyl-chain remodeling, cellular response to antibiotic, glycerophospholipid biosynthetic process, icosanoid biosynthetic process, icosanoid metabolic process, phosphatidic acid biosynthetic process, phosphatidylcholine acyl-chain remodeling, phosphatidylethanolamine acyl-chain remodeling, phosphatidylglycerol acyl-chain remodeling, phosphatidylinositol acyl-chain remodeling, phosphatidylserine acyl-chain remodeling, phospholipid catabolic process, phospholipid metabolic process, platelet activating factor biosynthetic process, platelet activation, regulation of cell proliferation, small molecule metabolic process Golgi apparatus, cytoplasmic membrane-bounded vesicle, cytosol, endoplasmic reticulum membrane, mitochondrial inner membrane calcium ion binding, calcium-dependent phospholipase A2 activity, calcium-dependent phospholipid binding, lysophospholipase activity, phospholipase A2 activity, phospholipase activity Human PLA2G4B Reactome UniProtKB {GO:0019369=PMID:10085124, GO:0019722=PMID:10085124, GO:0007567=PMID:10085124, GO:0036148=Reactome:REACT_121324, GO:0005509=PMID:10085124, GO:0005743=Reactome:REACT_120924, GO:0005576=PMID:10085124, GO:0044281=Reactome:REACT_111217, GO:0030968=Reactome:REACT_18356, GO:0005829=Reactome:REACT_121387, GO:0005544=PMID:10085124, GO:0036150=Reactome:REACT_121384, GO:0006954=PMID:10085124, GO:0031901=GO_REF:0000039, GO:0004622=PMID:10358058, GO:0047498=PMID:10085124, GO:0006987=Reactome:REACT_18368, GO:0006644=Reactome:REACT_120977, GO:0046475=PMID:10085124, GO:0044267=Reactome:REACT_17015, GO:0006654=Reactome:REACT_120906, GO:0036151=Reactome:REACT_120829, GO:0046474=Reactome:REACT_121401, GO:0036152=Reactome:REACT_121369} P0C869 Cytosolic phospholipase A2 beta protein 20130301 {GO:0019369=NAS, GO:0019722=NAS, GO:0007567=NAS, GO:0036148=TAS, GO:0005509=NAS, GO:0005743=TAS, GO:0005576=TAS, GO:0044281=TAS, GO:0030968=TAS, GO:0005829=TAS, GO:0005544=NAS, GO:0036150=TAS, GO:0006954=NAS, GO:0031901=IEA, GO:0004622=NAS, GO:0047498=IDA, GO:0006987=TAS, GO:0006644=TAS, GO:0046475=IDA, GO:0044267=TAS, GO:0006654=TAS, GO:0036151=TAS, GO:0046474=TAS, GO:0036152=TAS} activation of signaling protein activity involved in unfolded protein response, arachidonic acid metabolic process, calcium-mediated signaling, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, glycerophospholipid biosynthetic process, glycerophospholipid catabolic process, inflammatory response, parturition, phosphatidic acid biosynthetic process, phosphatidylcholine acyl-chain remodeling, phosphatidylethanolamine acyl-chain remodeling, phosphatidylglycerol acyl-chain remodeling, phosphatidylserine acyl-chain remodeling, phospholipid metabolic process, small molecule metabolic process cytosol, early endosome membrane, extracellular region, mitochondrial inner membrane calcium ion binding, calcium-dependent phospholipase A2 activity, calcium-dependent phospholipid binding, lysophospholipase activity Human PLA2G4C Reactome UniProtKB {GO:0019369=PMID:10085124, GO:0007567=PMID:10085124, GO:0036149=Reactome:REACT_120722, GO:0044281=Reactome:REACT_111217, GO:0004620=GO_REF:0000002, GO:0005829=PMID:10085124, GO:0035556=PMID:10085124, GO:0006954=PMID:10085124, GO:0005543=PMID:10085124, GO:0016020=PMID:10085124, GO:0047499=PMID:10085124, GO:0008152=GO_REF:0000002, GO:0005789=Reactome:REACT_121263, GO:0006644=Reactome:REACT_120977, GO:0046475=PMID:10085124, GO:0009395=GO_REF:0000002, GO:0036151=Reactome:REACT_120829, GO:0046474=Reactome:REACT_121401, GO:0036152=Reactome:REACT_121369} Q9UP65 Cytosolic phospholipase A2 gamma protein 20130301 {GO:0019369=NAS, GO:0007567=NAS, GO:0036149=TAS, GO:0044281=TAS, GO:0004620=IEA, GO:0005829=TAS, GO:0035556=NAS, GO:0006954=NAS, GO:0005543=NAS, GO:0016020=TAS, GO:0047499=IDA, GO:0008152=IEA, GO:0005789=TAS, GO:0006644=TAS, GO:0046475=IDA, GO:0009395=IEA, GO:0036151=TAS, GO:0046474=TAS, GO:0036152=TAS} arachidonic acid metabolic process, glycerophospholipid biosynthetic process, glycerophospholipid catabolic process, inflammatory response, intracellular signal transduction, metabolic process, parturition, phosphatidylcholine acyl-chain remodeling, phosphatidylethanolamine acyl-chain remodeling, phosphatidylinositol acyl-chain remodeling, phospholipid catabolic process, phospholipid metabolic process, small molecule metabolic process cytosol, endoplasmic reticulum membrane, membrane calcium-independent phospholipase A2 activity, phospholipase activity, phospholipid binding Human PLA2G4D Reactome UniProtKB {GO:0036149=Reactome:REACT_120722, GO:0036148=Reactome:REACT_121324, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_121405, GO:0036150=Reactome:REACT_121384, GO:0004623=GO_REF:0000003, GO:0006644=Reactome:REACT_120977, GO:0009395=GO_REF:0000002, GO:0006654=Reactome:REACT_120906, GO:0030659=GO_REF:0000039, GO:0036151=Reactome:REACT_120829, GO:0046474=Reactome:REACT_121401, GO:0036152=Reactome:REACT_121369} Q86XP0 Cytosolic phospholipase A2 delta protein 20130301 {GO:0036149=TAS, GO:0036148=TAS, GO:0044281=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0036150=TAS, GO:0004623=IEA, GO:0006644=TAS, GO:0009395=IEA, GO:0006654=TAS, GO:0030659=IEA, GO:0036151=TAS, GO:0046474=TAS, GO:0036152=TAS} glycerophospholipid biosynthetic process, phosphatidic acid biosynthetic process, phosphatidylcholine acyl-chain remodeling, phosphatidylethanolamine acyl-chain remodeling, phosphatidylglycerol acyl-chain remodeling, phosphatidylinositol acyl-chain remodeling, phosphatidylserine acyl-chain remodeling, phospholipid catabolic process, phospholipid metabolic process, small molecule metabolic process cytoplasmic vesicle membrane, cytosol metal ion binding, phospholipase A2 activity Human PLA2G4F Reactome UniProtKB {GO:0036149=Reactome:REACT_120722, GO:0036148=Reactome:REACT_121324, GO:0032587=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0004620=GO_REF:0000002, GO:0005765=GO_REF:0000039, GO:0031982=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_121405, GO:0036150=Reactome:REACT_121384, GO:0071407=GO_REF:0000019, GO:0001516=GO_REF:0000019, GO:0004622=GO_REF:0000019, GO:0047498=GO_REF:0000019, GO:0006644=Reactome:REACT_120977, GO:0009395=GO_REF:0000002, GO:0036151=Reactome:REACT_120829, GO:0071236=GO_REF:0000019, GO:0046474=Reactome:REACT_121401, GO:0036152=Reactome:REACT_121369, GO:0050482=GO_REF:0000019} Q68DD2 Cytosolic phospholipase A2 zeta protein 20130301 {GO:0036149=TAS, GO:0036148=TAS, GO:0032587=IEA, GO:0044281=TAS, GO:0004620=IEA, GO:0005765=IEA, GO:0031982=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0036150=TAS, GO:0071407=IEA, GO:0001516=IEA, GO:0004622=IEA, GO:0047498=IEA, GO:0006644=TAS, GO:0009395=IEA, GO:0036151=TAS, GO:0071236=IEA, GO:0046474=TAS, GO:0036152=TAS, GO:0050482=IEA} arachidonic acid secretion, cellular response to antibiotic, cellular response to organic cyclic compound, glycerophospholipid biosynthetic process, phosphatidylcholine acyl-chain remodeling, phosphatidylethanolamine acyl-chain remodeling, phosphatidylglycerol acyl-chain remodeling, phosphatidylinositol acyl-chain remodeling, phosphatidylserine acyl-chain remodeling, phospholipid catabolic process, phospholipid metabolic process, prostaglandin biosynthetic process, small molecule metabolic process cytosol, lysosomal membrane, ruffle membrane, vesicle calcium-dependent phospholipase A2 activity, lysophospholipase activity, metal ion binding, phospholipase activity Human PLA2G5 Reactome UniProtKB {GO:0019370=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0005794=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0036149=Reactome:REACT_120722, GO:0006663=GO_REF:0000019, GO:0036148=Reactome:REACT_121324, GO:0005509=GO_REF:0000002, GO:0005576=Reactome:REACT_121397, GO:0044281=Reactome:REACT_111217, GO:0051591=GO_REF:0000019, GO:0016042=GO_REF:0000037, GO:0036150=Reactome:REACT_121384, GO:0047498=GO_REF:0000019, GO:0006644=Reactome:REACT_120870, GO:0034097=GO_REF:0000019, GO:0006654=Reactome:REACT_120906, GO:0008201=GO_REF:0000019, GO:0036151=Reactome:REACT_120829, GO:0046474=Reactome:REACT_121401, GO:0036152=Reactome:REACT_121369, GO:0050482=GO_REF:0000019} P39877 Calcium-dependent phospholipase A2 protein 20111102 {GO:0019370=IEA, GO:0048471=IEA, GO:0005794=IEA, GO:0005886=IEA, GO:0009986=IEA, GO:0036149=TAS, GO:0006663=IEA, GO:0036148=TAS, GO:0005509=IEA, GO:0005576=TAS, GO:0044281=TAS, GO:0051591=IEA, GO:0016042=IEA, GO:0036150=TAS, GO:0047498=IEA, GO:0006644=TAS, GO:0034097=IEA, GO:0006654=TAS, GO:0008201=IEA, GO:0036151=TAS, GO:0046474=TAS, GO:0036152=TAS, GO:0050482=IEA} arachidonic acid secretion, glycerophospholipid biosynthetic process, leukotriene biosynthetic process, lipid catabolic process, phosphatidic acid biosynthetic process, phosphatidylcholine acyl-chain remodeling, phosphatidylethanolamine acyl-chain remodeling, phosphatidylglycerol acyl-chain remodeling, phosphatidylinositol acyl-chain remodeling, phosphatidylserine acyl-chain remodeling, phospholipid metabolic process, platelet activating factor biosynthetic process, response to cAMP, response to cytokine stimulus, small molecule metabolic process Golgi apparatus, cell surface, extracellular region, perinuclear region of cytoplasm, plasma membrane calcium ion binding, calcium-dependent phospholipase A2 activity, heparin binding Human PLA2G7 BHF-UCL UniProtKB {GO:0016042=GO_REF:0000037, GO:0005543=PMID:8624782, GO:0034440=PMID:8624782, GO:0034374=PMID:8624782, GO:0047499=PMID:8624782, GO:0034441=PMID:8624782, GO:0050729=PMID:8624782, GO:0034362=PMID:8624782, GO:0005576=Reactome:REACT_19294, GO:0090026=PMID:8624782, GO:0003847=GO_REF:0000003, GO:0044267=Reactome:REACT_17015} Q13093 Platelet-activating factor acetylhydrolase protein 20110711 {GO:0016042=IEA, GO:0005543=IDA, GO:0034440=IDA, GO:0034374=IDA, GO:0047499=IDA, GO:0034441=IDA, GO:0050729=TAS, GO:0034362=IDA, GO:0005576=TAS, GO:0090026=IDA, GO:0003847=IEA, GO:0044267=TAS} cellular protein metabolic process, lipid catabolic process, lipid oxidation, low-density lipoprotein particle remodeling, plasma lipoprotein particle oxidation, positive regulation of inflammatory response, positive regulation of monocyte chemotaxis extracellular region, low-density lipoprotein particle 1-alkyl-2-acetylglycerophosphocholine esterase activity, calcium-independent phospholipase A2 activity, phospholipid binding Human PLA2R1 UniProtKB UniProtKB {GO:0009986=PMID:15611272, GO:0072593=PMID:19197340, GO:0090238=GO_REF:0000024, GO:0090403=PMID:19197340, GO:0005576=GO_REF:0000024, GO:0001816=PMID:15611272, GO:0006898=GO_REF:0000019, GO:0043274=GO_REF:0000019, GO:0043517=PMID:19197340, GO:1900138=GO_REF:0000024, GO:0030246=GO_REF:0000002, GO:1900139=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0090399=PMID:19197340} Q13018 Secretory phospholipase A2 receptor protein 20111007 {GO:0009986=IDA, GO:0072593=IDA, GO:0090238=ISS, GO:0090403=IMP, GO:0005576=ISS, GO:0001816=IMP, GO:0006898=IEA, GO:0043274=IEA, GO:0043517=IMP, GO:1900138=ISS, GO:0030246=IEA, GO:1900139=ISS, GO:0016021=IEA, GO:0090399=IMP} cytokine production, negative regulation of arachidonic acid secretion, negative regulation of phospholipase A2 activity, oxidative stress-induced premature senescence, positive regulation of DNA damage response, signal transduction by p53 class mediator, positive regulation of arachidonic acid secretion, reactive oxygen species metabolic process, receptor-mediated endocytosis, replicative senescence cell surface, extracellular region, integral to membrane carbohydrate binding, phospholipase binding Human PLAA IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0016005=GO_REF:0000019, GO:0007165=PMID:9931468, GO:0006954=GO_REF:0000019, GO:0006644=PMID:9931468} Q9Y263 Phospholipase A-2-activating protein protein 20130415 {GO:0005515=IPI, GO:0016005=IEA, GO:0007165=TAS, GO:0006954=IEA, GO:0006644=TAS} inflammatory response, phospholipid metabolic process, signal transduction phospholipase A2 activator activity, protein binding Human UniProtKB:Q76353 PLAC1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0090214=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0001890=PMID:10995572, GO:0005575=GO_REF:0000015} Q9HBJ0 Placenta-specific protein 1 protein 20061026 {GO:0003674=ND, GO:0090214=IEA, GO:0005576=IEA, GO:0001890=IEP, GO:0005575=ND} placenta development, spongiotrophoblast layer developmental growth cellular_component, extracellular region molecular_function Human PLAC1L UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q86WS3 Placenta-specific 1-like protein protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 PLAC8 ENSEMBL UniProtKB {GO:0043066=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0040015=GO_REF:0000019, GO:0050873=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0009409=GO_REF:0000019, GO:0042742=GO_REF:0000019} Q9NZF1 Placenta-specific gene 8 protein protein 20130413 {GO:0043066=IEA, GO:0008284=IEA, GO:0040015=IEA, GO:0050873=IEA, GO:0045944=IEA, GO:0003682=IEA, GO:0009409=IEA, GO:0042742=IEA} brown fat cell differentiation, defense response to bacterium, negative regulation of apoptotic process, negative regulation of multicellular organism growth, positive regulation of cell proliferation, positive regulation of transcription from RNA polymerase II promoter, response to cold chromatin binding Human Ensembl:ENSMUSP00000108531 PLAC9 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q5JTB6 Placenta-specific protein 9 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 PLAG1 GOC UniProtKB {GO:0060736=GO_REF:0000019, GO:0003700=PMID:9722527, GO:0006366=GO_REF:0000033, GO:0006357=GO_REF:0000033, GO:0000981=GO_REF:0000033, GO:0005634=GO_REF:0000033, GO:0060252=GO_REF:0000019, GO:0006917=GO_REF:0000033, GO:0003677=GO_REF:0000037, GO:0010628=GO_REF:0000019, GO:0035264=GO_REF:0000019, GO:0035265=GO_REF:0000019, GO:0010629=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0022612=GO_REF:0000019} Q6DJT9 Zinc finger protein PLAG1 protein 20130413 {GO:0060736=IEA, GO:0003700=TAS, GO:0006366=IBA, GO:0006357=IBA, GO:0000981=IBA, GO:0005634=IBA, GO:0060252=IEA, GO:0006917=IBA, GO:0003677=IEA, GO:0010628=IEA, GO:0035264=IEA, GO:0035265=IEA, GO:0010629=IEA, GO:0008270=IEA, GO:0022612=IEA} gland morphogenesis, induction of apoptosis, multicellular organism growth, negative regulation of gene expression, organ growth, positive regulation of gene expression, positive regulation of glial cell proliferation, prostate gland growth, regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter nucleus DNA binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity, zinc ion binding Human PANTHER:PTN000003381 PLAGL1 GOC UniProtKB {GO:0010468=GO_REF:0000019, GO:0006366=GO_REF:0000033, GO:0045944=PMID:15888726, GO:0000981=GO_REF:0000033, GO:0007050=PMID:9184226, GO:0005634=GO_REF:0000033, GO:0008270=GO_REF:0000002, GO:0006917=PMID:9671765, GO:0003676=GO_REF:0000002, GO:0003677=PMID:15888725, GO:0030154=GO_REF:0000033} Q9UM63 Zinc finger protein PLAGL1 protein 20130413 {GO:0010468=IEA, GO:0006366=IBA, GO:0045944=IDA, GO:0000981=IBA, GO:0007050=TAS, GO:0005634=IBA, GO:0008270=IEA, GO:0006917=TAS, GO:0003676=IEA, GO:0003677=IDA, GO:0030154=IBA} cell cycle arrest, cell differentiation, induction of apoptosis, positive regulation of transcription from RNA polymerase II promoter, regulation of gene expression, transcription from RNA polymerase II promoter nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, zinc ion binding Human PANTHER:PTN000003381 PLAGL2 PINC UniProtKB {GO:0043565=PMID:15361364, GO:0006629=GO_REF:0000019, GO:0001077=PMID:15361364, GO:0003700=PMID:9722527, GO:0005634=GO_REF:0000033, GO:0008270=GO_REF:0000002, GO:0006917=GO_REF:0000033, GO:0009791=GO_REF:0000019, GO:0034378=GO_REF:0000033} Q9UPG8 Zinc finger protein PLAGL2 protein 20030904 {GO:0043565=IDA, GO:0006629=IEA, GO:0001077=IDA, GO:0003700=TAS, GO:0005634=IBA, GO:0008270=IEA, GO:0006917=IBA, GO:0009791=IEA, GO:0034378=IBA} chylomicron assembly, induction of apoptosis, lipid metabolic process, post-embryonic development nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human PLAT BHF-UCL UniProtKB {GO:0005515=PMID:8508955, GO:0004252=PMID:8508955, GO:0045202=GO_REF:0000019, GO:0043434=GO_REF:0000019, GO:0005615=GO_REF:0000039, GO:0051591=GO_REF:0000019, GO:0005737=PMID:1632457, GO:0048167=GO_REF:0000019, GO:0006508=GO_REF:0000019, GO:0030141=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0009986=PMID:1632457, GO:0035249=GO_REF:0000019, GO:0045177=GO_REF:0000019, GO:0014909=GO_REF:0000019, GO:0005576=Reactome:REACT_16891, GO:0051384=GO_REF:0000019, GO:0045861=PMID:1695900, GO:0031012=PMID:1632457, GO:0007596=Reactome:REACT_604, GO:0042060=GO_REF:0000019, GO:0048008=GO_REF:0000019, GO:0042730=Reactome:REACT_641, GO:0006464=PMID:3087818, GO:0060279=GO_REF:0000019} P00750 Tissue-type plasminogen activator protein 20100219 {GO:0005515=IPI, GO:0004252=IDA, GO:0045202=IEA, GO:0043434=IEA, GO:0005615=IEA, GO:0051591=IEA, GO:0005737=IDA, GO:0048167=IEA, GO:0006508=IEA, GO:0030141=IEA, GO:0001666=IEA, GO:0009986=IDA, GO:0035249=IEA, GO:0045177=IEA, GO:0014909=IEA, GO:0005576=TAS, GO:0051384=IEA, GO:0045861=IDA, GO:0031012=IDA, GO:0007596=TAS, GO:0042060=IEA, GO:0048008=IEA, GO:0042730=TAS, GO:0006464=TAS, GO:0060279=IEA} blood coagulation, cellular protein modification process, fibrinolysis, negative regulation of proteolysis, platelet-derived growth factor receptor signaling pathway, positive regulation of ovulation, proteolysis, regulation of synaptic plasticity, response to cAMP, response to glucocorticoid stimulus, response to hypoxia, response to peptide hormone stimulus, smooth muscle cell migration, synaptic transmission, glutamatergic, wound healing apical part of cell, cell surface, cytoplasm, extracellular matrix, extracellular region, extracellular space, secretory granule, synapse protein binding, serine-type endopeptidase activity Human UniProtKB:P05121 PLAU BHF-UCL UniProtKB {GO:0005515=PMID:14696115, GO:0033628=PMID:8837777, GO:0001666=GO_REF:0000019, GO:0010469=PMID:8837777, GO:0004252=Reactome:REACT_739, GO:0005886=Reactome:REACT_1386, GO:0009986=PMID:18835034, GO:0014910=PMID:8837777, GO:0014909=GO_REF:0000019, GO:0005576=Reactome:REACT_1386, GO:2000097=PMID:8837777, GO:0005615=PMID:18835034, GO:0061041=PMID:8837777, GO:0007165=PMID:10749881, GO:0006935=PMID:10749881, GO:0007596=Reactome:REACT_604, GO:0042127=GO_REF:0000019, GO:0006508=GO_REF:0000037, GO:0042730=Reactome:REACT_641} P00749 Urokinase-type plasminogen activator protein 20100319 {GO:0005515=IPI, GO:0033628=IDA, GO:0001666=IEA, GO:0010469=IDA, GO:0004252=TAS, GO:0005886=TAS, GO:0009986=IDA, GO:0014910=IDA, GO:0014909=IEA, GO:0005576=TAS, GO:2000097=IDA, GO:0005615=IDA, GO:0061041=IC, GO:0007165=TAS, GO:0006935=TAS, GO:0007596=TAS, GO:0042127=IEA, GO:0006508=IEA, GO:0042730=TAS} blood coagulation, chemotaxis, fibrinolysis, proteolysis, regulation of cell adhesion mediated by integrin, regulation of cell proliferation, regulation of receptor activity, regulation of smooth muscle cell migration, regulation of smooth muscle cell-matrix adhesion, regulation of wound healing, response to hypoxia, signal transduction, smooth muscle cell migration cell surface, extracellular region, extracellular space, plasma membrane protein binding, serine-type endopeptidase activity Human PLAUR Reactome UniProtKB {GO:0006501=Reactome:REACT_1853, GO:0005515=PMID:18718938, GO:0005886=Reactome:REACT_1386, GO:0009986=PMID:12493773, GO:0016255=Reactome:REACT_1830, GO:0006928=PMID:1689240, GO:0005576=GO_REF:0000039, GO:0031225=GO_REF:0000037, GO:0030162=PMID:1689240, GO:0007165=PMID:10749881, GO:0006935=PMID:10749881, GO:0005887=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0030377=PMID:1689240, GO:0005789=Reactome:REACT_1978, GO:0005788=Reactome:REACT_1777, GO:0004872=PMID:1689240, GO:0016021=PMID:1689240, GO:0019899=PMID:14688365, GO:0044267=Reactome:REACT_17015, GO:0042730=Reactome:REACT_641, GO:0043687=Reactome:REACT_22161, GO:0019898=PMID:8049431} Q03405 Urokinase plasminogen activator surface receptor protein 20130301 {GO:0006501=TAS, GO:0005515=IPI, GO:0005886=TAS, GO:0009986=IDA, GO:0016255=TAS, GO:0006928=NAS, GO:0005576=IEA, GO:0031225=IEA, GO:0030162=NAS, GO:0007165=TAS, GO:0006935=TAS, GO:0005887=IEA, GO:0007596=TAS, GO:0030377=NAS, GO:0005789=TAS, GO:0005788=TAS, GO:0004872=NAS, GO:0016021=NAS, GO:0019899=IPI, GO:0044267=TAS, GO:0042730=TAS, GO:0043687=TAS, GO:0019898=TAS} C-terminal protein lipidation, attachment of GPI anchor to protein, blood coagulation, cellular component movement, cellular protein metabolic process, chemotaxis, fibrinolysis, post-translational protein modification, regulation of proteolysis, signal transduction anchored to membrane, cell surface, endoplasmic reticulum lumen, endoplasmic reticulum membrane, extracellular region, extrinsic to membrane, integral to membrane, integral to plasma membrane, plasma membrane U-plasminogen activator receptor activity, enzyme binding, protein binding, receptor activity Human PLB1 Reactome UniProtKB {GO:0006629=GO_REF:0000002, GO:0005886=Reactome:REACT_120933, GO:0007603=Reactome:REACT_160125, GO:0016788=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0001523=Reactome:REACT_24968, GO:0016298=GO_REF:0000002, GO:0016042=GO_REF:0000037, GO:0016324=GO_REF:0000039, GO:0004622=GO_REF:0000003, GO:0004623=GO_REF:0000003, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0036151=Reactome:REACT_120829, GO:0046474=Reactome:REACT_121401} Q6P1J6 Phospholipase B1, membrane-associated protein 20130301 {GO:0006629=IEA, GO:0005886=TAS, GO:0007603=TAS, GO:0016788=IEA, GO:0044281=TAS, GO:0001523=TAS, GO:0016298=IEA, GO:0016042=IEA, GO:0016324=IEA, GO:0004622=IEA, GO:0004623=IEA, GO:0016021=IEA, GO:0006644=TAS, GO:0036151=TAS, GO:0046474=TAS} glycerophospholipid biosynthetic process, lipid catabolic process, lipid metabolic process, phosphatidylcholine acyl-chain remodeling, phospholipid metabolic process, phototransduction, visible light, retinoid metabolic process, small molecule metabolic process apical plasma membrane, integral to membrane, plasma membrane hydrolase activity, acting on ester bonds, lipase activity, lysophospholipase activity, phospholipase A2 activity Human PLBD1 Reactome UniProtKB {GO:0016042=GO_REF:0000037, GO:0016787=GO_REF:0000037, GO:0036149=Reactome:REACT_120722, GO:0005576=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0006644=Reactome:REACT_120977, GO:0036151=Reactome:REACT_120829, GO:0046474=Reactome:REACT_121401, GO:0036152=Reactome:REACT_121369, GO:0005829=Reactome:REACT_121252} Q6P4A8 Phospholipase B-like 1 protein 20130301 {GO:0016042=IEA, GO:0016787=IEA, GO:0036149=TAS, GO:0005576=IEA, GO:0044281=TAS, GO:0006644=TAS, GO:0036151=TAS, GO:0046474=TAS, GO:0036152=TAS, GO:0005829=TAS} glycerophospholipid biosynthetic process, lipid catabolic process, phosphatidylcholine acyl-chain remodeling, phosphatidylethanolamine acyl-chain remodeling, phosphatidylinositol acyl-chain remodeling, phospholipid metabolic process, small molecule metabolic process cytosol, extracellular region hydrolase activity Human PLBD2 UniProtKB UniProtKB {GO:0016042=GO_REF:0000037, GO:0016787=GO_REF:0000037, GO:0043202=GO_REF:0000039} Q8NHP8 Putative phospholipase B-like 2 protein 20130413 {GO:0016042=IEA, GO:0016787=IEA, GO:0043202=IEA} lipid catabolic process lysosomal lumen hydrolase activity Human UniProtKB-SubCell:SL-0156 PLCB1 GOC UniProtKB {GO:0006629=GO_REF:0000002, GO:0005516=PMID:12821674, GO:0000790=GO_REF:0000024, GO:0021987=GO_REF:0000024, GO:0043647=Reactome:REACT_150312, GO:0046330=PMID:9500449, GO:0007268=Reactome:REACT_13685, GO:2000438=GO_REF:0000024, GO:0032735=GO_REF:0000024, GO:0005634=PMID:10760467, GO:0044281=Reactome:REACT_111217, GO:0042803=GO_REF:0000024, GO:0005829=Reactome:REACT_150328, GO:0035556=GO_REF:0000002, GO:0005737=PMID:11118617, GO:0000086=GO_REF:0000024, GO:0051318=GO_REF:0000024, GO:0040019=GO_REF:0000024, GO:0035723=PMID:11743656, GO:0045444=GO_REF:0000019, GO:0007613=GO_REF:0000024, GO:0004871=GO_REF:0000037, GO:2000560=GO_REF:0000024, GO:0070498=PMID:8872139, GO:0005521=GO_REF:0000019, GO:0035722=PMID:11743656, GO:0031965=GO_REF:0000039, GO:0080154=GO_REF:0000024, GO:0046488=GO_REF:0000024, GO:0005509=GO_REF:0000002, GO:0005546=PMID:12799190, GO:0007215=GO_REF:0000024, GO:0007213=GO_REF:0000024, GO:2000344=GO_REF:0000024, GO:0043547=PMID:1322796, GO:0016042=GO_REF:0000037, GO:0007165=PMID:11118617, GO:0008277=GO_REF:0000024, GO:0016607=PMID:12799190, GO:0048639=GO_REF:0000024, GO:0004435=GO_REF:0000024, GO:0045663=GO_REF:0000024, GO:0060466=GO_REF:0000024, GO:0048009=GO_REF:0000024, GO:0045893=GO_REF:0000024, GO:0019899=PMID:12799190, GO:0045892=GO_REF:0000024, GO:0005096=PMID:1322796} Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 protein 20130413 {GO:0006629=IEA, GO:0005516=IPI, GO:0000790=ISS, GO:0021987=ISS, GO:0043647=TAS, GO:0046330=IDA, GO:0007268=TAS, GO:2000438=ISS, GO:0032735=ISS, GO:0005634=NAS, GO:0044281=TAS, GO:0042803=ISS, GO:0005829=TAS, GO:0035556=IEA, GO:0005737=IDA, GO:0000086=ISS, GO:0051318=ISS, GO:0040019=ISS, GO:0035723=IDA, GO:0045444=IEA, GO:0007613=ISS, GO:0004871=IEA, GO:2000560=ISS, GO:0070498=IDA, GO:0005521=IEA, GO:0035722=IDA, GO:0031965=IEA, GO:0080154=ISS, GO:0046488=ISS, GO:0005509=IEA, GO:0005546=IDA, GO:0007215=ISS, GO:0007213=ISS, GO:2000344=ISS, GO:0043547=IDA, GO:0016042=IEA, GO:0007165=NAS, GO:0008277=ISS, GO:0016607=IDA, GO:0048639=ISS, GO:0004435=ISS, GO:0045663=ISS, GO:0060466=ISS, GO:0048009=ISS, GO:0045893=ISS, GO:0019899=IPI, GO:0045892=ISS, GO:0005096=IDA} G-protein coupled acetylcholine receptor signaling pathway, G1 phase, G2/M transition of mitotic cell cycle, activation of meiosis involved in egg activation, cerebral cortex development, fat cell differentiation, glutamate receptor signaling pathway, inositol phosphate metabolic process, insulin-like growth factor receptor signaling pathway, interleukin-1-mediated signaling pathway, interleukin-12-mediated signaling pathway, interleukin-15-mediated signaling pathway, intracellular signal transduction, lipid catabolic process, lipid metabolic process, memory, negative regulation of monocyte extravasation, negative regulation of transcription, DNA-dependent, phosphatidylinositol metabolic process, positive regulation of CD24 biosynthetic process, positive regulation of GTPase activity, positive regulation of JNK cascade, positive regulation of acrosome reaction, positive regulation of developmental growth, positive regulation of embryonic development, positive regulation of interleukin-12 production, positive regulation of myoblast differentiation, positive regulation of transcription, DNA-dependent, regulation of G-protein coupled receptor protein signaling pathway, regulation of fertilization, signal transduction, small molecule metabolic process, synaptic transmission cytoplasm, cytosol, nuclear chromatin, nuclear membrane, nuclear speck, nucleus GTPase activator activity, calcium ion binding, calmodulin binding, enzyme binding, lamin binding, phosphatidylinositol phospholipase C activity, phosphatidylinositol-4,5-bisphosphate binding, protein homodimerization activity, signal transducer activity Human PLCB2 InterPro UniProtKB {GO:0006629=GO_REF:0000002, GO:0043647=Reactome:REACT_150312, GO:0005509=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0007202=PMID:7649993, GO:0005829=Reactome:REACT_150328, GO:0016042=GO_REF:0000037, GO:0035556=GO_REF:0000002, GO:0004629=PMID:7649993, GO:0050913=GO_REF:0000019, GO:0004435=GO_REF:0000002, GO:0004871=GO_REF:0000037, GO:0006644=PMID:1644792} Q9BVT6 Phospholipase C, beta 2, isoform CRA_a protein 20130413 {GO:0006629=IEA, GO:0043647=TAS, GO:0005509=IEA, GO:0007268=TAS, GO:0044281=TAS, GO:0007202=TAS, GO:0005829=TAS, GO:0016042=IEA, GO:0035556=IEA, GO:0004629=TAS, GO:0050913=IEA, GO:0004435=IEA, GO:0004871=IEA, GO:0006644=TAS} activation of phospholipase C activity, inositol phosphate metabolic process, intracellular signal transduction, lipid catabolic process, lipid metabolic process, phospholipid metabolic process, sensory perception of bitter taste, small molecule metabolic process, synaptic transmission cytosol calcium ion binding, phosphatidylinositol phospholipase C activity, phospholipase C activity, signal transducer activity Human InterPro:IPR001192 PLCB3 BHF-UCL UniProtKB {GO:0005516=PMID:12821674, GO:0043647=Reactome:REACT_150312, GO:0005509=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_150328, GO:0035556=GO_REF:0000002, GO:0016042=GO_REF:0000037, GO:0003073=PMID:18468998, GO:0004629=PMID:7607669, GO:0043234=PMID:18468998, GO:0016020=GO_REF:0000039, GO:0004435=GO_REF:0000003, GO:0004871=GO_REF:0000037} Q01970 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 protein 20110303 {GO:0005516=IPI, GO:0043647=TAS, GO:0005509=IEA, GO:0007268=TAS, GO:0044281=TAS, GO:0005829=TAS, GO:0035556=IEA, GO:0016042=IEA, GO:0003073=IDA, GO:0004629=TAS, GO:0043234=IDA, GO:0016020=IEA, GO:0004435=IEA, GO:0004871=IEA} inositol phosphate metabolic process, intracellular signal transduction, lipid catabolic process, regulation of systemic arterial blood pressure, small molecule metabolic process, synaptic transmission cytosol, membrane, protein complex calcium ion binding, calmodulin binding, phosphatidylinositol phospholipase C activity, phospholipase C activity, signal transducer activity Human UniProtKB:P62158 PLCB4 UniProtKB UniProtKB {GO:0006629=GO_REF:0000002, GO:0043647=Reactome:REACT_150312, GO:0005509=GO_REF:0000002, GO:0014069=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0005790=GO_REF:0000019, GO:0005829=Reactome:REACT_150328, GO:0035556=GO_REF:0000002, GO:0016042=GO_REF:0000037, GO:0004629=PMID:8530101, GO:0004435=GO_REF:0000002, GO:0004871=GO_REF:0000038} Q5JYS9 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 protein 20130413 {GO:0006629=IEA, GO:0043647=TAS, GO:0005509=IEA, GO:0014069=IEA, GO:0005634=IEA, GO:0044281=TAS, GO:0005790=IEA, GO:0005829=TAS, GO:0035556=IEA, GO:0016042=IEA, GO:0004629=TAS, GO:0004435=IEA, GO:0004871=IEA} inositol phosphate metabolic process, intracellular signal transduction, lipid catabolic process, lipid metabolic process, small molecule metabolic process cytosol, nucleus, postsynaptic density, smooth endoplasmic reticulum calcium ion binding, phosphatidylinositol phospholipase C activity, phospholipase C activity, signal transducer activity Human UniProtKB-KW:KW-0807 PLCD1 BHF-UCL UniProtKB {GO:0043647=Reactome:REACT_150312, GO:0005886=Reactome:REACT_150377, GO:0005509=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0001525=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0032794=PMID:18434237, GO:0035556=GO_REF:0000002, GO:0016042=GO_REF:0000037, GO:0005737=PMID:15702972, GO:0005543=GO_REF:0000002, GO:0004435=GO_REF:0000003, GO:0042127=GO_REF:0000019, GO:0060716=GO_REF:0000019, GO:0004871=GO_REF:0000037, GO:0006644=PMID:9588182} P51178 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 protein 20081126 {GO:0043647=TAS, GO:0005886=TAS, GO:0005509=IEA, GO:0044281=TAS, GO:0001525=IEA, GO:0005829=IEA, GO:0032794=IPI, GO:0035556=IEA, GO:0016042=IEA, GO:0005737=IDA, GO:0005543=IEA, GO:0004435=IEA, GO:0042127=IEA, GO:0060716=IEA, GO:0004871=IEA, GO:0006644=TAS} angiogenesis, inositol phosphate metabolic process, intracellular signal transduction, labyrinthine layer blood vessel development, lipid catabolic process, phospholipid metabolic process, regulation of cell proliferation, small molecule metabolic process cytoplasm, cytosol, plasma membrane GTPase activating protein binding, calcium ion binding, phosphatidylinositol phospholipase C activity, phospholipid binding, signal transducer activity Human UniProtKB:O43182-4 PLCD3 Reactome UniProtKB {GO:0006629=GO_REF:0000002, GO:0043647=Reactome:REACT_150312, GO:0005886=Reactome:REACT_150377, GO:0005509=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0001525=GO_REF:0000019, GO:0032154=GO_REF:0000039, GO:0005829=GO_REF:0000019, GO:0035556=GO_REF:0000002, GO:0016042=GO_REF:0000037, GO:0005543=GO_REF:0000002, GO:0004435=GO_REF:0000003, GO:0042127=GO_REF:0000019, GO:0060716=GO_REF:0000019, GO:0004871=GO_REF:0000037} Q8N3E9 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 protein 20111213 {GO:0006629=IEA, GO:0043647=TAS, GO:0005886=TAS, GO:0005509=IEA, GO:0044281=TAS, GO:0001525=IEA, GO:0032154=IEA, GO:0005829=IEA, GO:0035556=IEA, GO:0016042=IEA, GO:0005543=IEA, GO:0004435=IEA, GO:0042127=IEA, GO:0060716=IEA, GO:0004871=IEA} angiogenesis, inositol phosphate metabolic process, intracellular signal transduction, labyrinthine layer blood vessel development, lipid catabolic process, lipid metabolic process, regulation of cell proliferation, small molecule metabolic process cleavage furrow, cytosol, plasma membrane calcium ion binding, phosphatidylinositol phospholipase C activity, phospholipid binding, signal transducer activity Human PLCD4 UniProtKB UniProtKB {GO:0016042=GO_REF:0000037, GO:0005622=GO_REF:0000019, GO:0035556=GO_REF:0000002, GO:0006629=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0005783=GO_REF:0000039, GO:0004435=GO_REF:0000003, GO:0005509=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0004871=GO_REF:0000037, GO:0007340=GO_REF:0000019} Q9BRC7 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 protein 20130413 {GO:0016042=IEA, GO:0005622=IEA, GO:0035556=IEA, GO:0006629=IEA, GO:0005543=IEA, GO:0016020=IEA, GO:0005783=IEA, GO:0004435=IEA, GO:0005509=IEA, GO:0005634=IEA, GO:0004871=IEA, GO:0007340=IEA} acrosome reaction, intracellular signal transduction, lipid catabolic process, lipid metabolic process endoplasmic reticulum, intracellular, membrane, nucleus calcium ion binding, phosphatidylinositol phospholipase C activity, phospholipid binding, signal transducer activity Human UniProtKB-SubCell:SL-0162 PLCE1 HPA UniProtKB {GO:0045859=PMID:11022047, GO:0005515=PMID:11022048, GO:0019722=PMID:11022047, GO:0043647=Reactome:REACT_150312, GO:0005886=Reactome:REACT_150377, GO:0008283=PMID:11022048, GO:0007200=PMID:11022047, GO:0007265=PMID:11022048, GO:0044281=Reactome:REACT_111217, GO:0046578=PMID:11022047, GO:0006940=PMID:11022047, GO:0007204=PMID:11022047, GO:0001558=PMID:11022047, GO:0032835=PMID:17086182, GO:0007205=PMID:11022048, GO:0005829=PMID:11022048, GO:0005085=PMID:11022047, GO:0007507=PMID:11022047, GO:0004629=PMID:11022047, GO:0000187=PMID:11022047, GO:0005737=GO_REF:0000052, GO:0007173=PMID:11022048, GO:0007010=PMID:11022047, GO:0006651=PMID:11022047, GO:0017016=PMID:11022048, GO:0005509=GO_REF:0000002, GO:0048016=PMID:11022047, GO:0016042=GO_REF:0000037, GO:0008277=PMID:11022047, GO:0000139=GO_REF:0000039, GO:0004435=PMID:11022047, GO:0005057=PMID:11022048, GO:0006644=PMID:11022048, GO:0019899=PMID:11022048} Q9P212 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 protein 20090616 {GO:0045859=IDA, GO:0005515=IPI, GO:0019722=TAS, GO:0043647=TAS, GO:0005886=TAS, GO:0008283=NAS, GO:0007200=IDA, GO:0007265=TAS, GO:0044281=TAS, GO:0046578=IDA, GO:0006940=TAS, GO:0007204=TAS, GO:0001558=TAS, GO:0032835=IMP, GO:0007205=NAS, GO:0005829=IDA, GO:0005085=TAS, GO:0007507=TAS, GO:0004629=IDA, GO:0000187=IDA, GO:0005737=IDA, GO:0007173=NAS, GO:0007010=NAS, GO:0006651=TAS, GO:0017016=TAS, GO:0005509=IEA, GO:0048016=TAS, GO:0016042=IEA, GO:0008277=IDA, GO:0000139=IEA, GO:0004435=IDA, GO:0005057=TAS, GO:0006644=IC, GO:0019899=IPI} Ras protein signal transduction, activation of MAPK activity, calcium-mediated signaling, cell proliferation, cytoskeleton organization, diacylglycerol biosynthetic process, elevation of cytosolic calcium ion concentration, epidermal growth factor receptor signaling pathway, glomerulus development, heart development, inositol phosphate metabolic process, inositol phosphate-mediated signaling, lipid catabolic process, phospholipase C-activating G-protein coupled receptor signaling pathway, phospholipid metabolic process, protein kinase C-activating G-protein coupled receptor signaling pathway, regulation of G-protein coupled receptor protein signaling pathway, regulation of Ras protein signal transduction, regulation of cell growth, regulation of protein kinase activity, regulation of smooth muscle contraction, small molecule metabolic process Golgi membrane, cytoplasm, cytosol, plasma membrane Ras GTPase binding, calcium ion binding, enzyme binding, guanyl-nucleotide exchange factor activity, phosphatidylinositol phospholipase C activity, phospholipase C activity, protein binding, receptor signaling protein activity Human PLCG1 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0050852=Reactome:REACT_12526, GO:0043647=Reactome:REACT_150312, GO:0005886=Reactome:REACT_160203, GO:0019221=Reactome:REACT_25229, GO:0044281=Reactome:REACT_111217, GO:0007202=Reactome:REACT_12079, GO:0050900=Reactome:REACT_12051, GO:0005829=Reactome:REACT_160294, GO:0035556=GO_REF:0000002, GO:0004629=Reactome:REACT_118781, GO:0005737=PMID:15702972, GO:0000186=Reactome:REACT_12005, GO:0005543=GO_REF:0000002, GO:0007173=Reactome:REACT_9417, GO:0008180=PMID:22561606, GO:0007411=Reactome:REACT_18266, GO:0030971=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0005168=PMID:15488758, GO:0005509=GO_REF:0000002, GO:0001701=GO_REF:0000019, GO:0001726=PMID:17229814, GO:0045766=PMID:20011604, GO:0030027=PMID:17229814, GO:0007165=Reactome:REACT_12478, GO:0043536=PMID:20011604, GO:0008543=Reactome:REACT_9470, GO:0007596=Reactome:REACT_604, GO:0004435=Reactome:REACT_12585, GO:0071364=PMID:17229814, GO:0045087=Reactome:REACT_6802, GO:0019048=GO_REF:0000037, GO:0035254=GO_REF:0000019, GO:0005057=PMID:7681365, GO:0010634=PMID:17229814, GO:0038096=Reactome:REACT_160123, GO:0009395=GO_REF:0000002} P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 protein 20130415 {GO:0005515=IPI, GO:0050852=TAS, GO:0043647=TAS, GO:0005886=TAS, GO:0019221=TAS, GO:0044281=TAS, GO:0007202=TAS, GO:0050900=TAS, GO:0005829=TAS, GO:0035556=IEA, GO:0004629=TAS, GO:0005737=IDA, GO:0000186=TAS, GO:0005543=IEA, GO:0007173=TAS, GO:0008180=IDA, GO:0007411=TAS, GO:0030971=IEA, GO:0048011=TAS, GO:0005168=IPI, GO:0005509=IEA, GO:0001701=IEA, GO:0001726=IDA, GO:0045766=IDA, GO:0030027=IDA, GO:0007165=TAS, GO:0043536=IDA, GO:0008543=TAS, GO:0007596=TAS, GO:0004435=TAS, GO:0071364=IDA, GO:0045087=TAS, GO:0019048=IEA, GO:0035254=IEA, GO:0005057=NAS, GO:0010634=IMP, GO:0038096=TAS, GO:0009395=IEA} Fc-gamma receptor signaling pathway involved in phagocytosis, T cell receptor signaling pathway, activation of MAPKK activity, activation of phospholipase C activity, axon guidance, blood coagulation, cellular response to epidermal growth factor stimulus, cytokine-mediated signaling pathway, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, in utero embryonic development, innate immune response, inositol phosphate metabolic process, intracellular signal transduction, leukocyte migration, neurotrophin TRK receptor signaling pathway, phospholipid catabolic process, positive regulation of angiogenesis, positive regulation of blood vessel endothelial cell migration, positive regulation of epithelial cell migration, signal transduction, small molecule metabolic process, virus-host interaction cytoplasm, cytosol, lamellipodium, plasma membrane, ruffle, signalosome calcium ion binding, glutamate receptor binding, neurotrophin TRKA receptor binding, phosphatidylinositol phospholipase C activity, phospholipase C activity, phospholipid binding, protein binding, receptor signaling protein activity, receptor tyrosine kinase binding Human UniProtKB:Q9UPX8 PLCG2 IntAct UniProtKB {GO:0005515=PMID:15644415, GO:0010468=GO_REF:0000019, GO:0006629=GO_REF:0000002, GO:0050853=GO_REF:0000024, GO:0050852=GO_REF:0000024, GO:0019722=PMID:11043765, GO:0043647=Reactome:REACT_150312, GO:0005886=Reactome:REACT_160203, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_160294, GO:0035556=GO_REF:0000002, GO:0043069=GO_REF:0000019, GO:0004629=Reactome:REACT_118781, GO:0032237=GO_REF:0000019, GO:0032959=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0030183=GO_REF:0000024, GO:0032496=GO_REF:0000019, GO:0004871=GO_REF:0000037, GO:0016055=PMID:18784435, GO:0008081=GO_REF:0000002, GO:0051209=PMID:11606584, GO:0006661=PMID:12181444, GO:0030168=Reactome:REACT_798, GO:0004435=PMID:12181444, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0002316=GO_REF:0000019, GO:0038096=Reactome:REACT_160123, GO:0009395=GO_REF:0000002} P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 protein 20130415 {GO:0005515=IPI, GO:0010468=IEA, GO:0006629=IEA, GO:0050853=ISS, GO:0050852=ISS, GO:0019722=NAS, GO:0043647=TAS, GO:0005886=TAS, GO:0044281=TAS, GO:0005829=TAS, GO:0035556=IEA, GO:0043069=IEA, GO:0004629=TAS, GO:0032237=IEA, GO:0032959=IEA, GO:0005543=IEA, GO:0030183=ISS, GO:0032496=IEA, GO:0004871=IEA, GO:0016055=TAS, GO:0008081=IEA, GO:0051209=IDA, GO:0006661=IDA, GO:0030168=TAS, GO:0004435=IDA, GO:0007596=TAS, GO:0045087=TAS, GO:0002316=IEA, GO:0038096=TAS, GO:0009395=IEA} B cell differentiation, B cell receptor signaling pathway, Fc-gamma receptor signaling pathway involved in phagocytosis, T cell receptor signaling pathway, Wnt receptor signaling pathway, activation of store-operated calcium channel activity, blood coagulation, calcium-mediated signaling, follicular B cell differentiation, innate immune response, inositol phosphate metabolic process, inositol trisphosphate biosynthetic process, intracellular signal transduction, lipid metabolic process, negative regulation of programmed cell death, phosphatidylinositol biosynthetic process, phospholipid catabolic process, platelet activation, regulation of gene expression, release of sequestered calcium ion into cytosol, response to lipopolysaccharide, small molecule metabolic process cytosol, plasma membrane phosphatidylinositol phospholipase C activity, phospholipase C activity, phospholipid binding, phosphoric diester hydrolase activity, protein binding, signal transducer activity Human UniProtKB:P19235 PLCH1 HPA UniProtKB {GO:0031965=GO_REF:0000052, GO:0005886=Reactome:REACT_150377, GO:0043647=Reactome:REACT_150312, GO:0048015=PMID:15702972, GO:0050429=PMID:15702972, GO:0005509=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0043231=GO_REF:0000052, GO:0005829=GO_REF:0000019, GO:0016042=GO_REF:0000037, GO:0005737=PMID:15702972, GO:0005543=GO_REF:0000002, GO:0004435=GO_REF:0000003, GO:0004871=GO_REF:0000037} Q4KWH8 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 protein 20110516 {GO:0031965=IDA, GO:0005886=TAS, GO:0043647=TAS, GO:0048015=IDA, GO:0050429=IDA, GO:0005509=IEA, GO:0044281=TAS, GO:0043231=IDA, GO:0005829=IEA, GO:0016042=IEA, GO:0005737=IDA, GO:0005543=IEA, GO:0004435=IEA, GO:0004871=IEA} inositol phosphate metabolic process, lipid catabolic process, phosphatidylinositol-mediated signaling, small molecule metabolic process cytoplasm, cytosol, intracellular membrane-bounded organelle, nuclear membrane, plasma membrane calcium ion binding, calcium-dependent phospholipase C activity, phosphatidylinositol phospholipase C activity, phospholipid binding, signal transducer activity Human PLCH2 Reactome UniProtKB {GO:0006629=GO_REF:0000002, GO:0043647=Reactome:REACT_150312, GO:0005886=Reactome:REACT_150377, GO:0005509=GO_REF:0000002, GO:0046488=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0005575=GO_REF:0000015, GO:0035556=GO_REF:0000002, GO:0016042=GO_REF:0000037, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0004435=GO_REF:0000003, GO:0004871=GO_REF:0000037} O75038 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 protein 20111213 {GO:0006629=IEA, GO:0043647=TAS, GO:0005886=TAS, GO:0005509=IEA, GO:0046488=IEA, GO:0044281=TAS, GO:0005575=ND, GO:0035556=IEA, GO:0016042=IEA, GO:0008150=ND, GO:0003674=ND, GO:0005737=IEA, GO:0005543=IEA, GO:0004435=IEA, GO:0004871=IEA} biological_process, inositol phosphate metabolic process, intracellular signal transduction, lipid catabolic process, lipid metabolic process, phosphatidylinositol metabolic process, small molecule metabolic process cellular_component, cytoplasm, plasma membrane calcium ion binding, molecular_function, phosphatidylinositol phospholipase C activity, phospholipid binding, signal transducer activity Human PLCL1 PINC UniProtKB {GO:0035556=GO_REF:0000002, GO:0006629=GO_REF:0000002, GO:0004629=PMID:7633416, GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0004435=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0007610=GO_REF:0000019, GO:0004871=GO_REF:0000037} Q15111 Inactive phospholipase C-like protein 1 protein 20030904 {GO:0035556=IEA, GO:0006629=IEA, GO:0004629=TAS, GO:0005737=IEA, GO:0005543=IEA, GO:0004435=IEA, GO:0005509=IEA, GO:0007610=IEA, GO:0004871=IEA} behavior, intracellular signal transduction, lipid metabolic process cytoplasm calcium ion binding, phosphatidylinositol phospholipase C activity, phospholipase C activity, phospholipid binding, signal transducer activity Human PLCL2 UniProtKB UniProtKB {GO:0035556=GO_REF:0000002, GO:0006629=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0004435=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0004871=GO_REF:0000037} Q9UPR0 Inactive phospholipase C-like protein 2 protein 20130413 {GO:0035556=IEA, GO:0006629=IEA, GO:0005737=IEA, GO:0005543=IEA, GO:0004435=IEA, GO:0005509=IEA, GO:0004871=IEA} intracellular signal transduction, lipid metabolic process cytoplasm calcium ion binding, phosphatidylinositol phospholipase C activity, phospholipid binding, signal transducer activity Human UniProtKB-SubCell:SL-0086 PLCXD1 InterPro UniProtKB {GO:0006629=GO_REF:0000002, GO:0008081=GO_REF:0000002} Q9NUJ7 PI-PLC X domain-containing protein 1 protein 20130413 {GO:0006629=IEA, GO:0008081=IEA} lipid metabolic process phosphoric diester hydrolase activity Human InterPro:IPR017946 PLCXD2 UniProtKB UniProtKB {GO:0016042=GO_REF:0000037, GO:0006629=GO_REF:0000002, GO:0008081=GO_REF:0000002, GO:0004871=GO_REF:0000037} Q0VAA5 PI-PLC X domain-containing protein 2 protein 20130413 {GO:0016042=IEA, GO:0006629=IEA, GO:0008081=IEA, GO:0004871=IEA} lipid catabolic process, lipid metabolic process phosphoric diester hydrolase activity, signal transducer activity Human UniProtKB-KW:KW-0442 PLD1 Reactome UniProtKB {GO:0048471=GO_REF:0000039, GO:0005794=PMID:14718562, GO:0050830=GO_REF:0000019, GO:0007264=PMID:8530346, GO:0007265=PMID:10848592, GO:0004630=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0016042=GO_REF:0000037, GO:0007154=GO_REF:0000002, GO:0000139=GO_REF:0000039, GO:0006935=PMID:10848592, GO:0016020=PMID:8530346, GO:0070290=GO_REF:0000003, GO:0031902=GO_REF:0000039, GO:0005789=Reactome:REACT_121350, GO:0006644=Reactome:REACT_120870, GO:0035091=GO_REF:0000002, GO:0006654=Reactome:REACT_120906, GO:0006655=Reactome:REACT_121280, GO:0046474=Reactome:REACT_121401, GO:0005768=PMID:14718562} Q13393 Phospholipase D1 protein 20130301 {GO:0048471=IEA, GO:0005794=IDA, GO:0050830=IEA, GO:0007264=TAS, GO:0007265=TAS, GO:0004630=IEA, GO:0044281=TAS, GO:0003824=IEA, GO:0016042=IEA, GO:0007154=IEA, GO:0000139=IEA, GO:0006935=TAS, GO:0016020=TAS, GO:0070290=IEA, GO:0031902=IEA, GO:0005789=TAS, GO:0006644=TAS, GO:0035091=IEA, GO:0006654=TAS, GO:0006655=TAS, GO:0046474=TAS, GO:0005768=IDA} Ras protein signal transduction, cell communication, chemotaxis, defense response to Gram-positive bacterium, glycerophospholipid biosynthetic process, lipid catabolic process, phosphatidic acid biosynthetic process, phosphatidylglycerol biosynthetic process, phospholipid metabolic process, small GTPase mediated signal transduction, small molecule metabolic process Golgi apparatus, Golgi membrane, endoplasmic reticulum membrane, endosome, late endosome membrane, membrane, perinuclear region of cytoplasm NAPE-specific phospholipase D activity, catalytic activity, phosphatidylinositol binding, phospholipase D activity Human PLD2 Reactome UniProtKB {GO:0005886=Reactome:REACT_160135, GO:0007264=PMID:9582313, GO:0004630=GO_REF:0000003, GO:0031526=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0002031=GO_REF:0000019, GO:0016042=GO_REF:0000037, GO:0007154=GO_REF:0000002, GO:0070290=GO_REF:0000003, GO:0045087=Reactome:REACT_6802, GO:0007010=PMID:9395408, GO:0005789=Reactome:REACT_121350, GO:0006644=Reactome:REACT_120870, GO:0035091=GO_REF:0000002, GO:0006654=Reactome:REACT_120906, GO:0038096=Reactome:REACT_160123, GO:0006655=Reactome:REACT_121280, GO:0046474=Reactome:REACT_121401} O14939 Phospholipase D2 protein 20130301 {GO:0005886=TAS, GO:0007264=TAS, GO:0004630=IEA, GO:0031526=IEA, GO:0044281=TAS, GO:0003824=IEA, GO:0002031=IEA, GO:0016042=IEA, GO:0007154=IEA, GO:0070290=IEA, GO:0045087=TAS, GO:0007010=TAS, GO:0005789=TAS, GO:0006644=TAS, GO:0035091=IEA, GO:0006654=TAS, GO:0038096=TAS, GO:0006655=TAS, GO:0046474=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, G-protein coupled receptor internalization, cell communication, cytoskeleton organization, glycerophospholipid biosynthetic process, innate immune response, lipid catabolic process, phosphatidic acid biosynthetic process, phosphatidylglycerol biosynthetic process, phospholipid metabolic process, small GTPase mediated signal transduction, small molecule metabolic process brush border membrane, endoplasmic reticulum membrane, plasma membrane NAPE-specific phospholipase D activity, catalytic activity, phosphatidylinositol binding, phospholipase D activity Human PLD3 IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0016042=GO_REF:0000037, GO:0070290=GO_REF:0000003, GO:0005789=GO_REF:0000039, GO:0004630=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0003824=GO_REF:0000002, GO:0006655=Reactome:REACT_121280, GO:0046474=Reactome:REACT_121401} Q8IV08 Phospholipase D3 protein 20130415 {GO:0005515=IPI, GO:0016042=IEA, GO:0070290=IEA, GO:0005789=IEA, GO:0004630=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0006644=TAS, GO:0003824=IEA, GO:0006655=TAS, GO:0046474=TAS} glycerophospholipid biosynthetic process, lipid catabolic process, phosphatidylglycerol biosynthetic process, phospholipid metabolic process, small molecule metabolic process endoplasmic reticulum membrane, integral to membrane NAPE-specific phospholipase D activity, catalytic activity, phospholipase D activity, protein binding Human UniProtKB:P19838 PLD4 Reactome UniProtKB {GO:0016042=GO_REF:0000037, GO:0043647=Reactome:REACT_150312, GO:0004435=Reactome:REACT_150317, GO:0070290=GO_REF:0000003, GO:0005789=Reactome:REACT_150317, GO:0004630=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0003824=GO_REF:0000002, GO:0006655=Reactome:REACT_121280, GO:0046474=Reactome:REACT_121401} Q96BZ4 Phospholipase D4 protein 20130301 {GO:0016042=IEA, GO:0043647=TAS, GO:0004435=TAS, GO:0070290=IEA, GO:0005789=TAS, GO:0004630=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0006644=TAS, GO:0003824=IEA, GO:0006655=TAS, GO:0046474=TAS} glycerophospholipid biosynthetic process, inositol phosphate metabolic process, lipid catabolic process, phosphatidylglycerol biosynthetic process, phospholipid metabolic process, small molecule metabolic process endoplasmic reticulum membrane, integral to membrane NAPE-specific phospholipase D activity, catalytic activity, phosphatidylinositol phospholipase C activity, phospholipase D activity Human PLD5 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0003824=GO_REF:0000002} Q8N7P1 Inactive phospholipase D5 protein 20130413 {GO:0016021=IEA, GO:0003824=IEA} integral to membrane catalytic activity Human UniProtKB-KW:KW-0812 PLD6 Reactome UniProtKB {GO:0030719=GO_REF:0000024, GO:0007286=GO_REF:0000024, GO:0005741=PMID:21397848, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0042803=PMID:17028579, GO:0016042=GO_REF:0000037, GO:0004519=GO_REF:0000037, GO:0008053=PMID:17028579, GO:0007126=GO_REF:0000024, GO:0034587=GO_REF:0000024, GO:0035755=PMID:21397848, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0006655=Reactome:REACT_121280, GO:0046474=Reactome:REACT_121401, GO:0043046=GO_REF:0000024} Q8N2A8 Mitochondrial cardiolipin hydrolase protein 20130301 {GO:0030719=ISS, GO:0007286=ISS, GO:0005741=IDA, GO:0044281=TAS, GO:0046872=IEA, GO:0042803=IDA, GO:0016042=IEA, GO:0004519=IEA, GO:0008053=IMP, GO:0007126=ISS, GO:0034587=ISS, GO:0035755=IDA, GO:0016021=IEA, GO:0006644=TAS, GO:0006655=TAS, GO:0046474=TAS, GO:0043046=ISS} DNA methylation involved in gamete generation, P granule organization, glycerophospholipid biosynthetic process, lipid catabolic process, meiosis, mitochondrial fusion, phosphatidylglycerol biosynthetic process, phospholipid metabolic process, piRNA metabolic process, small molecule metabolic process, spermatid development integral to membrane, mitochondrial outer membrane cardiolipin hydrolase activity, endonuclease activity, metal ion binding, protein homodimerization activity Human PLEC BHF-UCL UniProtKB {GO:0005515=PMID:19932097, GO:0030056=PMID:12482924, GO:0005886=PMID:8633055, GO:0034329=Reactome:REACT_20676, GO:0030506=PMID:21223964, GO:0006915=Reactome:REACT_578, GO:0003779=GO_REF:0000037, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_20660, GO:0042383=PMID:21109228, GO:0016528=PMID:21223964, GO:0005737=GO_REF:0000052, GO:0043292=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0043034=PMID:21223964, GO:0031581=Reactome:REACT_20537, GO:0045111=GO_REF:0000052, GO:0008307=PMID:8696340, GO:0005925=GO_REF:0000052} Q15149 Plectin protein 20120606 {GO:0005515=IPI, GO:0030056=IDA, GO:0005886=NAS, GO:0034329=TAS, GO:0030506=IPI, GO:0006915=TAS, GO:0003779=IEA, GO:0006921=TAS, GO:0005829=TAS, GO:0042383=IDA, GO:0016528=ISS, GO:0005737=IDA, GO:0043292=IEA, GO:0030198=TAS, GO:0043034=TAS, GO:0031581=TAS, GO:0045111=IDA, GO:0008307=TAS, GO:0005925=IDA} apoptotic process, cell junction assembly, cellular component disassembly involved in execution phase of apoptosis, extracellular matrix organization, hemidesmosome assembly contractile fiber, costamere, cytoplasm, cytosol, focal adhesion, hemidesmosome, intermediate filament cytoskeleton, plasma membrane, sarcolemma, sarcoplasm actin binding, ankyrin binding, protein binding, structural constituent of muscle Human PLEK BHF-UCL UniProtKB {GO:0005515=PMID:8999861, GO:0060305=PMID:10995449, GO:0033625=GO_REF:0000024, GO:0031529=PMID:10497244, GO:0042803=PMID:8694752, GO:0005829=Reactome:REACT_21347, GO:0006904=GO_REF:0000024, GO:0005737=PMID:9060471, GO:0010925=PMID:8999861, GO:0070493=PMID:7782310, GO:0002244=PMID:2768345, GO:0032233=PMID:10497244, GO:0030836=PMID:10497244, GO:0005080=PMID:8615792, GO:0010572=GO_REF:0000024, GO:0010920=PMID:7559487, GO:0045744=PMID:7782310, GO:0031532=PMID:10497244, GO:0043325=PMID:15698571, GO:0046488=PMID:7559487, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_21347, GO:0032587=PMID:9060471, GO:0070528=GO_REF:0000024, GO:0070527=GO_REF:0000024, GO:0070560=GO_REF:0000024, GO:0030845=PMID:7782310, GO:0007596=Reactome:REACT_604, GO:0007229=PMID:10995449, GO:0030866=PMID:10497244, GO:0002576=PMID:7559487, GO:0030030=PMID:9060471, GO:0050849=PMID:8999861} P08567 Pleckstrin protein 20090506 {GO:0005515=IPI, GO:0060305=IDA, GO:0033625=ISS, GO:0031529=IDA, GO:0042803=IDA, GO:0005829=TAS, GO:0006904=ISS, GO:0005737=IDA, GO:0010925=IDA, GO:0070493=IDA, GO:0002244=IEP, GO:0032233=IDA, GO:0030836=IDA, GO:0005080=IDA, GO:0010572=ISS, GO:0010920=IDA, GO:0045744=IDA, GO:0031532=IDA, GO:0043325=IDA, GO:0046488=IDA, GO:0030168=TAS, GO:0005576=TAS, GO:0032587=IDA, GO:0070528=ISS, GO:0070527=ISS, GO:0070560=ISS, GO:0030845=IDA, GO:0007596=TAS, GO:0007229=IDA, GO:0030866=IDA, GO:0002576=IEP, GO:0030030=IDA, GO:0050849=NAS} actin cytoskeleton reorganization, blood coagulation, cell projection organization, cortical actin cytoskeleton organization, hematopoietic progenitor cell differentiation, integrin-mediated signaling pathway, negative regulation of G-protein coupled receptor protein signaling pathway, negative regulation of calcium-mediated signaling, negative regulation of inositol phosphate biosynthetic process, phosphatidylinositol metabolic process, phospholipase C-inhibiting G-protein coupled receptor signaling pathway, platelet activation, platelet aggregation, platelet degranulation, positive regulation of actin filament bundle assembly, positive regulation of actin filament depolymerization, positive regulation of inositol-polyphosphate 5-phosphatase activity, positive regulation of integrin activation, positive regulation of platelet activation, protein kinase C signaling cascade, protein secretion by platelet, regulation of cell diameter, ruffle organization, thrombin receptor signaling pathway, vesicle docking involved in exocytosis cytoplasm, cytosol, extracellular region, ruffle membrane phosphatidylinositol-3,4-bisphosphate binding, protein binding, protein homodimerization activity, protein kinase C binding Human UniProtKB:Q9JHK5 PLEK2 PINC UniProtKB {GO:0035556=GO_REF:0000002, GO:0005737=GO_REF:0000037, GO:0030036=PMID:10419454, GO:0005543=GO_REF:0000002, GO:0031258=GO_REF:0000039, GO:0005856=GO_REF:0000039} Q9NYT0 Pleckstrin-2 protein 20030904 {GO:0035556=IEA, GO:0005737=IEA, GO:0030036=TAS, GO:0005543=IEA, GO:0031258=IEA, GO:0005856=IEA} actin cytoskeleton organization, intracellular signal transduction cytoplasm, cytoskeleton, lamellipodium membrane phospholipid binding Human PLEKHA1 HPA UniProtKB {GO:0051898=PMID:14516276, GO:0050853=PMID:12101241, GO:0005515=PMID:18654987, GO:0070301=PMID:14516276, GO:0005886=PMID:12101241, GO:0001553=GO_REF:0000019, GO:0048705=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0007283=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0031529=PMID:15485858, GO:0045184=PMID:14516276, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0035264=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:0008209=GO_REF:0000019, GO:0043325=PMID:17823121, GO:0005730=GO_REF:0000052, GO:0032587=PMID:12101241, GO:0030165=PMID:15485858, GO:0014065=PMID:12101241, GO:0008210=GO_REF:0000019, GO:0060325=GO_REF:0000019, GO:0033327=GO_REF:0000019, GO:0048008=GO_REF:0000019} Q9HB21 Pleckstrin homology domain-containing family A member 1 protein 20101115 {GO:0051898=IMP, GO:0050853=IDA, GO:0005515=IPI, GO:0070301=IDA, GO:0005886=IDA, GO:0001553=IEA, GO:0048705=IEA, GO:0005634=IDA, GO:0007283=IEA, GO:0009791=IEA, GO:0031529=IDA, GO:0045184=IDA, GO:0005737=IDA, GO:0005543=IEA, GO:0035264=IEA, GO:0060021=IEA, GO:0008209=IEA, GO:0043325=IDA, GO:0005730=IDA, GO:0032587=IDA, GO:0030165=IPI, GO:0014065=IDA, GO:0008210=IEA, GO:0060325=IEA, GO:0033327=IEA, GO:0048008=IEA} B cell receptor signaling pathway, Leydig cell differentiation, androgen metabolic process, cellular response to hydrogen peroxide, establishment of protein localization, estrogen metabolic process, face morphogenesis, luteinization, multicellular organism growth, negative regulation of protein kinase B signaling cascade, palate development, phosphatidylinositol 3-kinase cascade, platelet-derived growth factor receptor signaling pathway, post-embryonic development, ruffle organization, skeletal system morphogenesis, spermatogenesis cytoplasm, nucleolus, nucleus, plasma membrane, ruffle membrane PDZ domain binding, phosphatidylinositol-3,4-bisphosphate binding, phospholipid binding, protein binding Human PLEKHA2 UniProtKB UniProtKB {GO:0005515=PMID:19786618, GO:0043234=PMID:19786618, GO:0005545=GO_REF:0000019, GO:0005737=PMID:19786618, GO:0005543=GO_REF:0000002, GO:0016020=PMID:19786618, GO:0005886=GO_REF:0000039, GO:0043236=PMID:19786618, GO:0005634=GO_REF:0000039, GO:0001968=PMID:19786618, GO:0030165=GO_REF:0000019, GO:0001954=PMID:19786618} Q9HB19 Pleckstrin homology domain-containing family A member 2 protein 20100204 {GO:0005515=IPI, GO:0043234=IDA, GO:0005545=IEA, GO:0005737=IDA, GO:0005543=IEA, GO:0016020=IDA, GO:0005886=IEA, GO:0043236=IMP, GO:0005634=IEA, GO:0001968=IMP, GO:0030165=IEA, GO:0001954=IMP} positive regulation of cell-matrix adhesion cytoplasm, membrane, nucleus, plasma membrane, protein complex 1-phosphatidylinositol binding, PDZ domain binding, fibronectin binding, laminin binding, phospholipid binding, protein binding Human PLEKHA4 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0005545=PMID:11001876, GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0005575=GO_REF:0000015} Q9H4M7 Pleckstrin homology domain-containing family A member 4 protein 20061026 {GO:0008150=ND, GO:0005545=NAS, GO:0005737=IEA, GO:0005543=IEA, GO:0016020=IEA, GO:0005575=ND} biological_process cellular_component, cytoplasm, membrane 1-phosphatidylinositol binding, phospholipid binding Human PLEKHA5 IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0008150=GO_REF:0000015, GO:0005545=PMID:11001876, GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0005575=GO_REF:0000015} Q9HAU0 Pleckstrin homology domain-containing family A member 5 protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0005545=NAS, GO:0005737=IEA, GO:0005543=IEA, GO:0005575=ND} biological_process cellular_component, cytoplasm 1-phosphatidylinositol binding, phospholipid binding, protein binding Human UniProtKB:Q9NWB1 PLEKHA6 InterPro UniProtKB {GO:0005543=GO_REF:0000002} Q9Y2H5 Pleckstrin homology domain-containing family A member 6 protein 20130413 {GO:0005543=IEA} phospholipid binding Human InterPro:IPR001849 PLEKHA7 HPA UniProtKB {GO:0090136=PMID:19041755, GO:0005915=PMID:19041755, GO:0005813=PMID:19041755, GO:0005737=GO_REF:0000052, GO:0030054=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0070097=PMID:19041755, GO:0005634=GO_REF:0000052, GO:0045218=PMID:19041755} Q6IQ23 Pleckstrin homology domain-containing family A member 7 protein 20111111 {GO:0090136=IMP, GO:0005915=IDA, GO:0005813=IDA, GO:0005737=IDA, GO:0030054=IDA, GO:0005543=IEA, GO:0070097=IDA, GO:0005634=IDA, GO:0045218=IMP} epithelial cell-cell adhesion, zonula adherens maintenance cell junction, centrosome, cytoplasm, nucleus, zonula adherens delta-catenin binding, phospholipid binding Human PLEKHA8 UniProtKB UniProtKB {GO:0005802=PMID:15107860, GO:0035621=PMID:17687330, GO:0051861=PMID:17687330, GO:0005794=GO_REF:0000039, GO:0070273=PMID:15107860, GO:0015031=GO_REF:0000037, GO:0005737=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0017089=PMID:17687330, GO:0006869=PMID:17687330, GO:0046836=GO_REF:0000002, GO:0097001=PMID:17687330} Q96JA3 Pleckstrin homology domain-containing family A member 8 protein 20120806 {GO:0005802=IDA, GO:0035621=IDA, GO:0051861=IDA, GO:0005794=IEA, GO:0070273=IDA, GO:0015031=IEA, GO:0005737=IEA, GO:0005543=IEA, GO:0016020=IEA, GO:0017089=IDA, GO:0006869=IDA, GO:0046836=IEA, GO:0097001=IDA} ER to Golgi ceramide transport, glycolipid transport, lipid transport, protein transport Golgi apparatus, cytoplasm, membrane, trans-Golgi network ceramide binding, glycolipid binding, glycolipid transporter activity, phosphatidylinositol-4-phosphate binding, phospholipid binding Human PLEKHB1 PINC UniProtKB {GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0007275=GO_REF:0000037, GO:0045595=GO_REF:0000019, GO:0004871=PMID:10585447, GO:0016021=PMID:10585447, GO:0007602=PMID:10585447, GO:0008022=GO_REF:0000019, GO:0042803=GO_REF:0000019} Q9UF11 Pleckstrin homology domain-containing family B member 1 protein 20050308 {GO:0005737=IEA, GO:0005543=IEA, GO:0007275=IEA, GO:0045595=IEA, GO:0004871=TAS, GO:0016021=IDA, GO:0007602=NAS, GO:0008022=IEA, GO:0042803=IEA} multicellular organismal development, phototransduction, regulation of cell differentiation cytoplasm, integral to membrane phospholipid binding, protein C-terminus binding, protein homodimerization activity, signal transducer activity Human PLEKHB2 UniProtKB UniProtKB {GO:0005543=GO_REF:0000002, GO:0055038=GO_REF:0000039} Q96CS7 Pleckstrin homology domain-containing family B member 2 protein 20130413 {GO:0005543=IEA, GO:0055038=IEA} recycling endosome membrane phospholipid binding Human UniProtKB-SubCell:SL-0231 PLEKHD1 InterPro UniProtKB {GO:0005543=GO_REF:0000002} A6NEE1 Pleckstrin homology domain-containing family D member 1 protein 20130413 {GO:0005543=IEA} phospholipid binding Human InterPro:IPR001849 PLEKHF1 HPA UniProtKB {GO:0048471=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0070273=PMID:22115783, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0006917=GO_REF:0000019, GO:0032266=PMID:22115783, GO:0005765=PMID:22115783, GO:0072659=PMID:22115783, GO:0005764=PMID:22115783, GO:0046872=GO_REF:0000037, GO:0016050=PMID:22115783, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0007032=PMID:22115783, GO:0010314=PMID:22115783, GO:0010008=PMID:22115783, GO:0005768=PMID:22115783, GO:0010508=PMID:22115783} Q96S99 Pleckstrin homology domain-containing family F member 1 protein 20100326 {GO:0048471=IEA, GO:0005730=IDA, GO:0070273=IDA, GO:0006915=IEA, GO:0005634=IDA, GO:0006917=IEA, GO:0032266=IDA, GO:0005765=IC, GO:0072659=IMP, GO:0005764=IDA, GO:0046872=IEA, GO:0016050=IMP, GO:0005737=IDA, GO:0005543=IEA, GO:0007032=IMP, GO:0010314=IDA, GO:0010008=IC, GO:0005768=IDA, GO:0010508=IDA} apoptotic process, endosome organization, induction of apoptosis, positive regulation of autophagy, protein localization to plasma membrane, vesicle organization cytoplasm, endosome, endosome membrane, lysosomal membrane, lysosome, nucleolus, nucleus, perinuclear region of cytoplasm metal ion binding, phosphatidylinositol-3-phosphate binding, phosphatidylinositol-4-phosphate binding, phosphatidylinositol-5-phosphate binding, phospholipid binding Human PLEKHF2 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0030133=GO_REF:0000054, GO:0005543=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q9H8W4 Pleckstrin homology domain-containing family F member 2 protein 20130415 {GO:0005515=IPI, GO:0030133=IDA, GO:0005543=IEA, GO:0046872=IEA} transport vesicle metal ion binding, phospholipid binding, protein binding Human UniProtKB:Q9UKJ5 PLEKHG2 Reactome UniProtKB {GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0005543=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0035023=GO_REF:0000002, GO:0006915=Reactome:REACT_13638, GO:0005089=GO_REF:0000002, GO:0097190=Reactome:REACT_13720, GO:0005829=Reactome:REACT_19216} Q9H7P9 Pleckstrin homology domain-containing family G member 2 protein 20130301 {GO:0005622=IEA, GO:0051056=TAS, GO:0048011=TAS, GO:0005543=IEA, GO:0007264=TAS, GO:0035023=IEA, GO:0006915=TAS, GO:0005089=IEA, GO:0097190=TAS, GO:0005829=TAS} apoptotic process, apoptotic signaling pathway, neurotrophin TRK receptor signaling pathway, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol, intracellular Rho guanyl-nucleotide exchange factor activity, phospholipid binding Human PLEKHG3 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0035023=GO_REF:0000002, GO:0005089=GO_REF:0000002} G3V3I3 Pleckstrin homology domain-containing family G member 3 protein 20130413 {GO:0005622=IEA, GO:0005543=IEA, GO:0035023=IEA, GO:0005089=IEA} regulation of Rho protein signal transduction intracellular Rho guanyl-nucleotide exchange factor activity, phospholipid binding Human InterPro:IPR000219 PLEKHG4 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0035023=GO_REF:0000002, GO:0005089=GO_REF:0000002} Q58EX7 Puratrophin-1 protein 20130413 {GO:0005622=IEA, GO:0005543=IEA, GO:0035023=IEA, GO:0005089=IEA} regulation of Rho protein signal transduction intracellular Rho guanyl-nucleotide exchange factor activity, phospholipid binding Human InterPro:IPR000219 PLEKHG4B InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0035023=GO_REF:0000002, GO:0005089=GO_REF:0000002} Q96PX9 Pleckstrin homology domain-containing family G member 4B protein 20130413 {GO:0005622=IEA, GO:0005543=IEA, GO:0035023=IEA, GO:0005089=IEA} regulation of Rho protein signal transduction intracellular Rho guanyl-nucleotide exchange factor activity, phospholipid binding Human InterPro:IPR000219 PLEKHG5 InterPro UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0048471=GO_REF:0000039, GO:0048011=Reactome:REACT_13776, GO:0005886=GO_REF:0000019, GO:0035023=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0006915=Reactome:REACT_13638, GO:0097190=Reactome:REACT_13720, GO:0005829=Reactome:REACT_19216, GO:0005622=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0043542=GO_REF:0000019, GO:0004871=PMID:12761501, GO:0005089=GO_REF:0000002, GO:0043123=PMID:12761501} Q5SY18 Pleckstrin homology domain-containing family G member 5 protein 20130413 {GO:0051056=TAS, GO:0048471=IEA, GO:0048011=TAS, GO:0005886=IEA, GO:0035023=IEA, GO:0007264=TAS, GO:0006915=TAS, GO:0097190=TAS, GO:0005829=TAS, GO:0005622=IEA, GO:0005543=IEA, GO:0043542=IEA, GO:0004871=IMP, GO:0005089=IEA, GO:0043123=IMP} apoptotic process, apoptotic signaling pathway, endothelial cell migration, neurotrophin TRK receptor signaling pathway, positive regulation of I-kappaB kinase/NF-kappaB cascade, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol, intracellular, perinuclear region of cytoplasm, plasma membrane Rho guanyl-nucleotide exchange factor activity, phospholipid binding, signal transducer activity Human InterPro:IPR000219 PLEKHG6 UniProtKB UniProtKB {GO:0005515=PMID:19129481, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0000922=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0035023=GO_REF:0000002, GO:0005089=GO_REF:0000002, GO:0032154=GO_REF:0000039, GO:0005096=GO_REF:0000037} Q3KR16 Pleckstrin homology domain-containing family G member 6 protein 20110831 {GO:0005515=IPI, GO:0005622=IEA, GO:0005737=IEA, GO:0000922=IEA, GO:0005543=IEA, GO:0035023=IEA, GO:0005089=IEA, GO:0032154=IEA, GO:0005096=IEA} regulation of Rho protein signal transduction cleavage furrow, cytoplasm, intracellular, spindle pole GTPase activator activity, Rho guanyl-nucleotide exchange factor activity, phospholipid binding, protein binding Human UniProtKB:B2RX88 PLEKHH3 InterPro UniProtKB {GO:0007165=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0005856=GO_REF:0000002} Q7Z736 Pleckstrin homology domain-containing family H member 3 protein 20130413 {GO:0007165=IEA, GO:0005543=IEA, GO:0005856=IEA} signal transduction cytoskeleton phospholipid binding Human InterPro:IPR000159 PLEKHJ1 InterPro UniProtKB {GO:0005543=GO_REF:0000002} Q9NW61 Pleckstrin homology domain-containing family J member 1 protein 20130413 {GO:0005543=IEA} phospholipid binding Human InterPro:IPR001849 PLEKHM1 UniProtKB UniProtKB {GO:0035556=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q9Y4G2 Pleckstrin homology domain-containing family M member 1 protein 20130413 {GO:0035556=IEA, GO:0005737=IEA, GO:0005543=IEA, GO:0046872=IEA} intracellular signal transduction cytoplasm metal ion binding, phospholipid binding Human UniProtKB-SubCell:SL-0086 PLEKHM2 UniProtKB UniProtKB {GO:0005515=PMID:15905402, GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0007030=PMID:15905402, GO:0019894=PMID:15905402} Q8IWE5 Pleckstrin homology domain-containing family M member 2 protein 20091112 {GO:0005515=IPI, GO:0005737=IEA, GO:0005543=IEA, GO:0007030=IMP, GO:0019894=IDA} Golgi organization cytoplasm kinesin binding, phospholipid binding, protein binding Human UniProtKB:Q56061 PLEKHM3 UniProtKB UniProtKB {GO:0035556=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q6ZWE6 Pleckstrin homology domain-containing family M member 3 protein 20130413 {GO:0035556=IEA, GO:0005543=IEA, GO:0046872=IEA} intracellular signal transduction metal ion binding, phospholipid binding Human UniProtKB-KW:KW-0479 PLEKHO1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0005634=GO_REF:0000039} Q53GL0 Pleckstrin homology domain-containing family O member 1 protein 20130413 {GO:0005737=IEA, GO:0005543=IEA, GO:0005886=IEA, GO:0005634=IEA} cytoplasm, nucleus, plasma membrane phospholipid binding Human UniProtKB-SubCell:SL-0039 PLEKHO2 InterPro UniProtKB {GO:0005543=GO_REF:0000002} Q8TD55 Pleckstrin homology domain-containing family O member 2 protein 20130413 {GO:0005543=IEA} phospholipid binding Human InterPro:IPR001849 PLG ENSEMBL UniProtKB {GO:0005515=PMID:134998, GO:0043498=PMID:14699093, GO:0008285=PMID:8910613, GO:0048771=GO_REF:0000037, GO:0004252=PMID:14699093, GO:0005886=Reactome:REACT_2235, GO:0010812=PMID:14699093, GO:2000048=PMID:17203182, GO:0071674=GO_REF:0000019, GO:0042246=GO_REF:0000019, GO:0005615=PMID:6980881, GO:0046716=GO_REF:0000019, GO:0043231=GO_REF:0000019, GO:0022617=PMID:14699093, GO:0030198=Reactome:REACT_118779, GO:0051603=GO_REF:0000019, GO:0060716=GO_REF:0000019, GO:0045445=GO_REF:0000019, GO:0031093=Reactome:REACT_21351, GO:0019904=PMID:9786936, GO:0060707=GO_REF:0000019, GO:0051919=PMID:6438154, GO:0051918=PMID:14726399, GO:0006915=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_118776, GO:0006917=GO_REF:0000019, GO:0031232=PMID:14699093, GO:0004175=GO_REF:0000019, GO:0007596=PMID:1986355, GO:0002576=Reactome:REACT_318, GO:0034185=PMID:16480936, GO:0042730=Reactome:REACT_641, GO:0044267=Reactome:REACT_17015, GO:0019897=GO_REF:0000019} Q5TEH5 Angiostatin protein 20130413 {GO:0005515=IPI, GO:0043498=IDA, GO:0008285=TAS, GO:0048771=IEA, GO:0004252=IDA, GO:0005886=TAS, GO:0010812=IDA, GO:2000048=TAS, GO:0071674=IEA, GO:0042246=IEA, GO:0005615=IDA, GO:0046716=IEA, GO:0043231=IEA, GO:0022617=IDA, GO:0030198=TAS, GO:0051603=IEA, GO:0060716=IEA, GO:0045445=IEA, GO:0031093=TAS, GO:0019904=IPI, GO:0060707=IEA, GO:0051919=IDA, GO:0051918=IDA, GO:0006915=IEA, GO:0030168=TAS, GO:0005576=TAS, GO:0006917=IEA, GO:0031232=IDA, GO:0004175=IEA, GO:0007596=IMP, GO:0002576=TAS, GO:0034185=IPI, GO:0042730=TAS, GO:0044267=TAS, GO:0019897=IEA} apoptotic process, blood coagulation, cellular protein metabolic process, extracellular matrix disassembly, extracellular matrix organization, fibrinolysis, induction of apoptosis, labyrinthine layer blood vessel development, mononuclear cell migration, muscle cell homeostasis, myoblast differentiation, negative regulation of cell proliferation, negative regulation of cell-cell adhesion mediated by cadherin, negative regulation of cell-substrate adhesion, negative regulation of fibrinolysis, platelet activation, platelet degranulation, positive regulation of fibrinolysis, proteolysis involved in cellular protein catabolic process, tissue regeneration, tissue remodeling, trophoblast giant cell differentiation extracellular region, extracellular space, extrinsic to external side of plasma membrane, extrinsic to plasma membrane, intracellular membrane-bounded organelle, plasma membrane, platelet alpha granule lumen apolipoprotein binding, cell surface binding, endopeptidase activity, protein binding, protein domain specific binding, serine-type endopeptidase activity Human Ensembl:ENSMUSP00000014578 PLIN1 Reactome UniProtKB {GO:0005811=Reactome:REACT_27159, GO:0006629=Reactome:REACT_602, GO:0044281=Reactome:REACT_111217, GO:0019433=Reactome:REACT_494, GO:0008289=PMID:9521880} O60240 Perilipin-1 protein 20130213 {GO:0005811=TAS, GO:0006629=TAS, GO:0044281=TAS, GO:0019433=TAS, GO:0008289=NAS} lipid metabolic process, small molecule metabolic process, triglyceride catabolic process lipid particle lipid binding Human PLIN2 Reactome UniProtKB {GO:0005811=GO_REF:0000019, GO:0014070=GO_REF:0000019, GO:0005886=Reactome:REACT_115542, GO:0005783=PMID:9003395, GO:0019915=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0005576=PMID:9003395, GO:0005634=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0015909=GO_REF:0000019, GO:0044255=Reactome:REACT_22279} Q99541 Perilipin-2 protein 20130301 {GO:0005811=IEA, GO:0014070=IEA, GO:0005886=TAS, GO:0005783=TAS, GO:0019915=IEA, GO:0042493=IEA, GO:0005576=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0015909=IEA, GO:0044255=TAS} cellular lipid metabolic process, lipid storage, long-chain fatty acid transport, response to drug, response to organic cyclic compound, small molecule metabolic process endoplasmic reticulum, extracellular region, lipid particle, nucleus, plasma membrane Human PLIN3 HPA UniProtKB {GO:0005515=PMID:19490898, GO:0005737=GO_REF:0000052, GO:0005794=PMID:9590177, GO:0016192=PMID:9590177, GO:0010008=GO_REF:0000039, GO:0043231=GO_REF:0000052, GO:0005768=PMID:9590177} O60664 Perilipin-3 protein 20110516 {GO:0005515=IPI, GO:0005737=IDA, GO:0005794=TAS, GO:0016192=TAS, GO:0010008=IEA, GO:0043231=IDA, GO:0005768=TAS} vesicle-mediated transport Golgi apparatus, cytoplasm, endosome, endosome membrane, intracellular membrane-bounded organelle protein binding Human PLIN4 UniProtKB UniProtKB {GO:0005811=GO_REF:0000039, GO:0005886=GO_REF:0000039} Q96Q06 Perilipin-4 protein 20130413 {GO:0005811=IEA, GO:0005886=IEA} lipid particle, plasma membrane Human UniProtKB-SubCell:SL-0039 PLK1 BHF-UCL UniProtKB {GO:0005515=PMID:17146433, GO:0008017=PMID:12939256, GO:0007077=Reactome:REACT_160255, GO:0000236=Reactome:REACT_682, GO:0010997=PMID:18662541, GO:0000910=Reactome:REACT_1932, GO:0018105=PMID:16885022, GO:0016301=Reactome:REACT_147881, GO:0051443=PMID:19473992, GO:0010800=PMID:21041660, GO:0005813=PMID:21041660, GO:0019901=PMID:21041660, GO:0043393=PMID:21041660, GO:0005819=PMID:12939256, GO:0030496=PMID:19468300, GO:0000122=PMID:18174154, GO:0000922=PMID:21041660, GO:0000776=PMID:21041660, GO:0005654=Reactome:REACT_160188, GO:0000278=Reactome:REACT_152, GO:0007092=PMID:15148369, GO:0016567=PMID:16885022, GO:0008283=PMID:8127874, GO:0045736=PMID:21041660, GO:0001578=PMID:12939256, GO:0031572=PMID:18662541, GO:0032436=PMID:19473992, GO:0005634=PMID:18615013, GO:0051233=PMID:21041660, GO:0031145=Reactome:REACT_6828, GO:0005829=Reactome:REACT_160293, GO:0031648=PMID:16885022, GO:0000088=Reactome:REACT_765, GO:0000086=Reactome:REACT_2203, GO:0000087=Reactome:REACT_910, GO:0051726=Reactome:REACT_1006, GO:0005876=PMID:21041660, GO:0007091=Reactome:REACT_1016, GO:0043066=PMID:18174154, GO:0051437=Reactome:REACT_6904, GO:0005524=GO_REF:0000037, GO:0045862=PMID:16885022, GO:0051439=Reactome:REACT_6837, GO:0051297=PMID:8991084, GO:0007346=PMID:17495026, GO:0007067=PMID:18477460, GO:0004672=PMID:19596235, GO:0000942=PMID:18195732, GO:0004674=PMID:21041660, GO:0090007=PMID:21041660, GO:0006468=PMID:19468300, GO:0071168=PMID:21111234, GO:0000090=Reactome:REACT_1275} P53350 Serine/threonine-protein kinase PLK1 protein 20110202 {GO:0005515=IPI, GO:0008017=IDA, GO:0007077=TAS, GO:0000236=TAS, GO:0010997=IPI, GO:0000910=TAS, GO:0018105=IDA, GO:0016301=TAS, GO:0051443=IMP, GO:0010800=IMP, GO:0005813=IDA, GO:0019901=IPI, GO:0043393=IMP, GO:0005819=IDA, GO:0030496=IDA, GO:0000122=IMP, GO:0000922=IDA, GO:0000776=IDA, GO:0005654=TAS, GO:0000278=TAS, GO:0007092=IDA, GO:0016567=IDA, GO:0008283=TAS, GO:0045736=IMP, GO:0001578=IDA, GO:0031572=IDA, GO:0032436=IMP, GO:0005634=IDA, GO:0051233=IDA, GO:0031145=TAS, GO:0005829=TAS, GO:0031648=IDA, GO:0000088=TAS, GO:0000086=TAS, GO:0000087=TAS, GO:0051726=TAS, GO:0005876=IDA, GO:0007091=TAS, GO:0043066=IMP, GO:0051437=TAS, GO:0005524=IEA, GO:0045862=IDA, GO:0051439=TAS, GO:0051297=IMP, GO:0007346=IMP, GO:0007067=IMP, GO:0004672=IDA, GO:0000942=IDA, GO:0004674=IMP, GO:0090007=IMP, GO:0006468=IDA, GO:0071168=IDA, GO:0000090=TAS} G2 DNA damage checkpoint, G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, activation of mitotic anaphase-promoting complex activity, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell proliferation, centrosome organization, cytokinesis, metaphase/anaphase transition of mitotic cell cycle, microtubule bundle formation, mitosis, mitotic anaphase, mitotic cell cycle, mitotic nuclear envelope disassembly, mitotic prometaphase, mitotic prophase, negative regulation of apoptotic process, negative regulation of cyclin-dependent protein serine/threonine kinase activity, negative regulation of transcription from RNA polymerase II promoter, peptidyl-serine phosphorylation, positive regulation of peptidyl-threonine phosphorylation, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of proteolysis, positive regulation of ubiquitin-protein ligase activity, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein destabilization, protein localization to chromatin, protein phosphorylation, protein ubiquitination, regulation of cell cycle, regulation of mitotic anaphase, regulation of mitotic cell cycle, regulation of protein binding, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle centrosome, condensed nuclear chromosome outer kinetochore, cytosol, kinetochore, midbody, nucleoplasm, nucleus, spindle, spindle microtubule, spindle midzone, spindle pole ATP binding, anaphase-promoting complex binding, kinase activity, microtubule binding, protein binding, protein kinase activity, protein kinase binding, protein serine/threonine kinase activity Human PLK1S1 UniProtKB UniProtKB {GO:0005515=PMID:19536135, GO:0005813=PMID:16980960, GO:0005737=GO_REF:0000037, GO:0019901=PMID:16980960, GO:0007051=PMID:16980960} Q2M2Z5 Centrosomal protein kizuna protein 20090623 {GO:0005515=IPI, GO:0005813=IDA, GO:0005737=IEA, GO:0019901=IPI, GO:0007051=IMP} spindle organization centrosome, cytoplasm protein binding, protein kinase binding Human UniProtKB:Q9P209 PLK2 UniProtKB UniProtKB {GO:0005515=PMID:20352051, GO:0005813=PMID:15242618, GO:0007093=GO_REF:0000024, GO:0043066=GO_REF:0000024, GO:0032486=GO_REF:0000024, GO:0005814=PMID:19001868, GO:0007265=GO_REF:0000024, GO:0060291=GO_REF:0000024, GO:0060292=GO_REF:0000024, GO:0046599=PMID:19001868, GO:0005524=GO_REF:0000037, GO:0030425=GO_REF:0000024, GO:0005622=GO_REF:0000024, GO:0000082=PMID:15242618, GO:0004674=PMID:19001868, GO:0048167=GO_REF:0000024, GO:0006468=PMID:20352051, GO:0007613=GO_REF:0000024, GO:0004871=PMID:12761501, GO:0007052=PMID:19001868, GO:0043123=PMID:12761501} Q9NYY3 Serine/threonine-protein kinase PLK2 protein 20111122 {GO:0005515=IPI, GO:0005813=IDA, GO:0007093=ISS, GO:0043066=ISS, GO:0032486=ISS, GO:0005814=IDA, GO:0007265=ISS, GO:0060291=ISS, GO:0060292=ISS, GO:0046599=IDA, GO:0005524=IEA, GO:0030425=ISS, GO:0005622=ISS, GO:0000082=IMP, GO:0004674=IDA, GO:0048167=ISS, GO:0006468=IDA, GO:0007613=ISS, GO:0004871=IMP, GO:0007052=IDA, GO:0043123=IMP} G1/S transition of mitotic cell cycle, Rap protein signal transduction, Ras protein signal transduction, long term synaptic depression, long-term synaptic potentiation, memory, mitotic cell cycle checkpoint, mitotic spindle organization, negative regulation of apoptotic process, positive regulation of I-kappaB kinase/NF-kappaB cascade, protein phosphorylation, regulation of centriole replication, regulation of synaptic plasticity centriole, centrosome, dendrite, intracellular ATP binding, protein binding, protein serine/threonine kinase activity, signal transducer activity Human PLK3 PINC UniProtKB {GO:0005515=PMID:21264284, GO:0007093=PMID:21840391, GO:0005634=PMID:19490146, GO:0090166=PMID:14980500, GO:0030425=GO_REF:0000019, GO:0000084=PMID:17264206, GO:0002039=PMID:11447225, GO:0000910=PMID:21840391, GO:0000082=PMID:17264206, GO:0005737=PMID:19490146, GO:0000086=PMID:16481012, GO:0007113=PMID:21264284, GO:0043025=GO_REF:0000019, GO:2000777=PMID:20889502, GO:0009314=PMID:21376736, GO:0005813=PMID:16478733, GO:0043066=PMID:19490146, GO:0005795=PMID:14980500, GO:0005730=PMID:17264206, GO:0006915=PMID:16478733, GO:0006970=PMID:21098032, GO:0000122=PMID:19490146, GO:0005524=GO_REF:0000037, GO:0006974=PMID:16481012, GO:0004674=PMID:11447225, GO:0043491=GO_REF:0000024, GO:0000075=GO_REF:0000024, GO:0006468=PMID:8702627, GO:0000302=PMID:11447225} Q9H4B4 Serine/threonine-protein kinase PLK3 protein 20030904 {GO:0005515=IPI, GO:0007093=TAS, GO:0005634=IDA, GO:0090166=IDA, GO:0030425=IEA, GO:0000084=IMP, GO:0002039=IDA, GO:0000910=TAS, GO:0000082=IMP, GO:0005737=IDA, GO:0000086=TAS, GO:0007113=TAS, GO:0043025=IEA, GO:2000777=IDA, GO:0009314=IDA, GO:0005813=IDA, GO:0043066=IDA, GO:0005795=IDA, GO:0005730=IDA, GO:0006915=TAS, GO:0006970=IDA, GO:0000122=IDA, GO:0005524=IEA, GO:0006974=IMP, GO:0004674=IDA, GO:0043491=ISS, GO:0000075=ISS, GO:0006468=TAS, GO:0000302=IDA} G1/S transition of mitotic cell cycle, G2/M transition of mitotic cell cycle, Golgi disassembly, S phase of mitotic cell cycle, apoptotic process, cell cycle checkpoint, cytokinesis, endomitotic cell cycle, mitotic cell cycle checkpoint, negative regulation of apoptotic process, negative regulation of transcription from RNA polymerase II promoter, positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia, protein kinase B signaling cascade, protein phosphorylation, response to DNA damage stimulus, response to osmotic stress, response to radiation, response to reactive oxygen species Golgi stack, centrosome, cytoplasm, dendrite, neuronal cell body, nucleolus, nucleus ATP binding, p53 binding, protein binding, protein serine/threonine kinase activity Human PLK4 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0005813=PMID:21399614, GO:0007099=PMID:21725316, GO:0005814=PMID:17681131, GO:0060707=GO_REF:0000024, GO:0005730=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0032154=GO_REF:0000039, GO:0005829=Reactome:REACT_15470, GO:0046601=PMID:17681131, GO:0004674=PMID:21725316, GO:0000086=Reactome:REACT_2203, GO:0006468=PMID:10607900, GO:0004713=GO_REF:0000002, GO:0000278=Reactome:REACT_152} O00444 Serine/threonine-protein kinase PLK4 protein 20130415 {GO:0005515=IPI, GO:0005813=IDA, GO:0007099=IMP, GO:0005814=IDA, GO:0060707=ISS, GO:0005730=ISS, GO:0005524=IEA, GO:0032154=IEA, GO:0005829=TAS, GO:0046601=IMP, GO:0004674=IDA, GO:0000086=TAS, GO:0006468=TAS, GO:0004713=IEA, GO:0000278=TAS} G2/M transition of mitotic cell cycle, centriole replication, mitotic cell cycle, positive regulation of centriole replication, protein phosphorylation, trophoblast giant cell differentiation centriole, centrosome, cleavage furrow, cytosol, nucleolus ATP binding, protein binding, protein serine/threonine kinase activity, protein tyrosine kinase activity Human UniProtKB:P31947 PLLP ENSEMBL UniProtKB {GO:0043218=GO_REF:0000019, GO:0042552=GO_REF:0000019, GO:0009611=GO_REF:0000019, GO:0045121=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0006811=GO_REF:0000019} Q9Y342 Plasmolipin protein 20130413 {GO:0043218=IEA, GO:0042552=IEA, GO:0009611=IEA, GO:0045121=IEA, GO:0016021=IEA, GO:0006811=IEA} ion transport, myelination, response to wounding compact myelin, integral to membrane, membrane raft Human Ensembl:ENSRNOP00000022277 PLN BHF-UCL UniProtKB {GO:0005515=PMID:15598648, GO:0048471=GO_REF:0000024, GO:1901897=PMID:19708671, GO:1901020=PMID:19708671, GO:0005783=GO_REF:0000024, GO:1901895=PMID:19708671, GO:0008015=PMID:8406504, GO:1901877=PMID:19708671, GO:0042030=PMID:19708671, GO:0086092=GO_REF:0000019, GO:0090281=PMID:12032137, GO:0042802=GO_REF:0000024, GO:0060314=GO_REF:0000019, GO:0051924=GO_REF:0000024, GO:0086023=GO_REF:0000019, GO:0051117=PMID:12032137, GO:0051926=PMID:19708671, GO:0006816=GO_REF:0000019, GO:0086004=PMID:19708671, GO:0010459=PMID:16432188, GO:0004857=PMID:12032137, GO:0031966=GO_REF:0000039, GO:0005246=GO_REF:0000002, GO:0051480=PMID:19708671, GO:0010881=GO_REF:0000019, GO:0032780=PMID:19708671, GO:0031982=GO_REF:0000019, GO:0043086=PMID:12032137, GO:0048738=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0016529=GO_REF:0000039, GO:0016020=PMID:19708671, GO:0002026=PMID:19708671, GO:0055119=PMID:22679139, GO:0016021=GO_REF:0000037, GO:0086036=PMID:19708671} P26678 Cardiac phospholamban protein 20130206 {GO:0005515=IPI, GO:0048471=ISS, GO:1901897=IC, GO:1901020=IDA, GO:0005783=ISS, GO:1901895=IDA, GO:0008015=NAS, GO:1901877=IDA, GO:0042030=IDA, GO:0086092=IEA, GO:0090281=ISS, GO:0042802=ISS, GO:0060314=IEA, GO:0051924=ISS, GO:0086023=IEA, GO:0051117=ISS, GO:0051926=IDA, GO:0006816=IEA, GO:0086004=IC, GO:0010459=IMP, GO:0004857=ISS, GO:0031966=IEA, GO:0005246=IEA, GO:0051480=IC, GO:0010881=IEA, GO:0032780=IDA, GO:0031982=IEA, GO:0043086=ISS, GO:0048738=IEA, GO:0043234=IEA, GO:0016529=IEA, GO:0016020=IDA, GO:0002026=IC, GO:0055119=TAS, GO:0016021=IEA, GO:0086036=IC} adrenergic receptor signaling pathway involved in heart process, blood circulation, calcium ion transport, cardiac muscle tissue development, cytosolic calcium ion homeostasis, negative regulation of ATPase activity, negative regulation of calcium ion binding, negative regulation of calcium ion import, negative regulation of calcium ion transmembrane transporter activity, negative regulation of calcium ion transport, negative regulation of calcium-transporting ATPase activity, negative regulation of catalytic activity, negative regulation of heart rate, regulation of calcium ion transport, regulation of cardiac muscle cell contraction, regulation of cardiac muscle cell membrane potential, regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion, regulation of relaxation of cardiac muscle, regulation of ryanodine-sensitive calcium-release channel activity, regulation of the force of heart contraction, regulation of the force of heart contraction by cardiac conduction, relaxation of cardiac muscle endoplasmic reticulum, integral to membrane, membrane, mitochondrial membrane, perinuclear region of cytoplasm, protein complex, sarcoplasmic reticulum, vesicle ATPase binding, ATPase inhibitor activity, calcium channel regulator activity, enzyme inhibitor activity, identical protein binding, protein binding Human PLOD1 Reactome UniProtKB {GO:0001666=PMID:15174142, GO:0005581=GO_REF:0000038, GO:0031418=GO_REF:0000037, GO:0005506=GO_REF:0000002, GO:0005783=GO_REF:0000002, GO:0008475=GO_REF:0000003, GO:0042803=PMID:1577494, GO:0008544=PMID:8449506, GO:0030198=Reactome:REACT_118779, GO:0030867=GO_REF:0000039, GO:0005789=Reactome:REACT_120884, GO:0046947=PMID:1577494, GO:0016702=GO_REF:0000037, GO:0006464=PMID:1577494, GO:0055114=PMID:1577494} Q02809 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 protein 20111109 {GO:0001666=IEP, GO:0005581=IEA, GO:0031418=IEA, GO:0005506=IEA, GO:0005783=IEA, GO:0008475=IEA, GO:0042803=TAS, GO:0008544=IMP, GO:0030198=TAS, GO:0030867=IEA, GO:0005789=TAS, GO:0046947=TAS, GO:0016702=IEA, GO:0006464=NAS, GO:0055114=TAS} cellular protein modification process, epidermis development, extracellular matrix organization, hydroxylysine biosynthetic process, oxidation-reduction process, response to hypoxia collagen, endoplasmic reticulum, endoplasmic reticulum membrane, rough endoplasmic reticulum membrane L-ascorbic acid binding, iron ion binding, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, procollagen-lysine 5-dioxygenase activity, protein homodimerization activity Human PLOD2 Reactome UniProtKB {GO:0001666=PMID:15174142, GO:0005581=GO_REF:0000038, GO:0031418=GO_REF:0000037, GO:0005506=GO_REF:0000002, GO:0030198=Reactome:REACT_118779, GO:0005783=PMID:9054364, GO:0030867=GO_REF:0000039, GO:0005789=Reactome:REACT_120884, GO:0008475=GO_REF:0000003, GO:0016702=GO_REF:0000037, GO:0006464=PMID:9054364} O00469 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 protein 20111109 {GO:0001666=IEP, GO:0005581=IEA, GO:0031418=IEA, GO:0005506=IEA, GO:0030198=TAS, GO:0005783=TAS, GO:0030867=IEA, GO:0005789=TAS, GO:0008475=IEA, GO:0016702=IEA, GO:0006464=TAS} cellular protein modification process, extracellular matrix organization, response to hypoxia collagen, endoplasmic reticulum, endoplasmic reticulum membrane, rough endoplasmic reticulum membrane L-ascorbic acid binding, iron ion binding, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, procollagen-lysine 5-dioxygenase activity Human PLOD3 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0031418=GO_REF:0000037, GO:0005506=GO_REF:0000002, GO:0005783=PMID:9724729, GO:0060425=GO_REF:0000019, GO:0008475=GO_REF:0000003, GO:0033823=Reactome:REACT_120743, GO:0001701=GO_REF:0000019, GO:0032870=GO_REF:0000019, GO:0048730=GO_REF:0000019, GO:0008104=GO_REF:0000019, GO:0001886=GO_REF:0000019, GO:0070831=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0050211=Reactome:REACT_120777, GO:0030867=GO_REF:0000039, GO:0030199=GO_REF:0000019, GO:0042311=GO_REF:0000019, GO:0005789=Reactome:REACT_120884, GO:0021915=GO_REF:0000019, GO:0016702=GO_REF:0000037, GO:0006464=PMID:9724729} O60568 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 protein 20130415 {GO:0005515=IPI, GO:0031418=IEA, GO:0005506=IEA, GO:0005783=TAS, GO:0060425=IEA, GO:0008475=IEA, GO:0033823=TAS, GO:0001701=IEA, GO:0032870=IEA, GO:0048730=IEA, GO:0008104=IEA, GO:0001886=IEA, GO:0070831=IEA, GO:0030198=TAS, GO:0050211=TAS, GO:0030867=IEA, GO:0030199=IEA, GO:0042311=IEA, GO:0005789=TAS, GO:0021915=IEA, GO:0016702=IEA, GO:0006464=TAS} basement membrane assembly, cellular protein modification process, cellular response to hormone stimulus, collagen fibril organization, endothelial cell morphogenesis, epidermis morphogenesis, extracellular matrix organization, in utero embryonic development, lung morphogenesis, neural tube development, protein localization, vasodilation endoplasmic reticulum, endoplasmic reticulum membrane, rough endoplasmic reticulum membrane L-ascorbic acid binding, iron ion binding, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, procollagen galactosyltransferase activity, procollagen glucosyltransferase activity, procollagen-lysine 5-dioxygenase activity, protein binding Human UniProtKB:Q9BQY4 PLP1 PINC UniProtKB {GO:0010628=GO_REF:0000019, GO:0008219=GO_REF:0000037, GO:0005198=PMID:2479017, GO:0022010=GO_REF:0000019, GO:0007229=GO_REF:0000019, GO:0043209=GO_REF:0000019, GO:0042759=GO_REF:0000019, GO:0007268=PMID:2479017, GO:0048469=GO_REF:0000019, GO:0019911=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0008366=PMID:2479017} P60201 Myelin proteolipid protein protein 20061108 {GO:0010628=IEA, GO:0008219=IEA, GO:0005198=TAS, GO:0022010=IEA, GO:0007229=IEA, GO:0043209=IEA, GO:0042759=IEA, GO:0007268=TAS, GO:0048469=IEA, GO:0019911=IEA, GO:0016021=IEA, GO:0008366=TAS} axon ensheathment, cell death, cell maturation, central nervous system myelination, integrin-mediated signaling pathway, long-chain fatty acid biosynthetic process, positive regulation of gene expression, synaptic transmission integral to membrane, myelin sheath structural constituent of myelin sheath, structural molecule activity Human PLP2 GOC UniProtKB {GO:0034220=PMID:9124532, GO:0016020=PMID:9124532, GO:0006935=PMID:15474493, GO:0005886=PMID:15474493, GO:0015075=PMID:9124532, GO:0005783=PMID:9124532, GO:0019221=PMID:15474493, GO:0005789=PMID:9124532, GO:0016021=GO_REF:0000037, GO:0006811=PMID:9124532, GO:0019956=PMID:15474493} Q04941 Proteolipid protein 2 protein 20130413 {GO:0034220=TAS, GO:0016020=TAS, GO:0006935=NAS, GO:0005886=IDA, GO:0015075=TAS, GO:0005783=TAS, GO:0019221=NAS, GO:0005789=TAS, GO:0016021=IEA, GO:0006811=TAS, GO:0019956=IPI} chemotaxis, cytokine-mediated signaling pathway, ion transmembrane transport, ion transport endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, membrane, plasma membrane chemokine binding, ion transmembrane transporter activity Human PLRG1 GOC UniProtKB {GO:0005515=PMID:20176811, GO:0007165=PMID:9765207, GO:0016607=GO_REF:0000039, GO:0000398=PMID:11991638, GO:0003714=PMID:9765207, GO:0005634=PMID:9765207, GO:0004871=PMID:9765207, GO:0071013=PMID:11991638} O43660 Pleiotropic regulator 1 protein 20130413 {GO:0005515=IPI, GO:0007165=TAS, GO:0016607=IEA, GO:0000398=IC, GO:0003714=TAS, GO:0005634=TAS, GO:0004871=TAS, GO:0071013=IDA} mRNA splicing, via spliceosome, signal transduction catalytic step 2 spliceosome, nuclear speck, nucleus protein binding, signal transducer activity, transcription corepressor activity Human PLS1 PINC UniProtKB {GO:0005737=GO_REF:0000039, GO:0051015=PMID:8139549, GO:0005509=GO_REF:0000002, GO:0005200=PMID:8139549, GO:0003779=GO_REF:0000038} Q14651 Plastin-1 protein 20030904 {GO:0005737=IEA, GO:0051015=TAS, GO:0005509=IEA, GO:0005200=TAS, GO:0003779=IEA} cytoplasm actin binding, actin filament binding, calcium ion binding, structural constituent of cytoskeleton Human PLS3 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0003779=GO_REF:0000037} P13797 Plastin-3 protein 20130413 {GO:0005737=IEA, GO:0005509=IEA, GO:0003779=IEA} cytoplasm actin binding, calcium ion binding Human UniProtKB-SubCell:SL-0086 PLSCR1 IntAct UniProtKB {GO:2000373=PMID:17567603, GO:0005515=PMID:16189514, GO:0017121=PMID:10770950, GO:0005154=PMID:12009895, GO:0017124=PMID:11390389, GO:0005886=PMID:19333378, GO:0017128=PMID:10770950, GO:0035456=PMID:15308695, GO:0005634=PMID:20870722, GO:0033003=GO_REF:0000024, GO:0051607=PMID:15308695, GO:0042609=PMID:19333378, GO:0045944=PMID:16091359, GO:0045071=PMID:15308695, GO:0005794=PMID:12586838, GO:0005509=PMID:18629440, GO:0005730=PMID:17567603, GO:0030168=PMID:9218461, GO:0006915=PMID:10770950, GO:0006953=GO_REF:0000024, GO:0003677=GO_REF:0000037, GO:0010628=PMID:15308695, GO:0031012=PMID:20870722, GO:0001077=PMID:16091359, GO:0045089=PMID:15308695, GO:0005887=PMID:12586838, GO:0045121=PMID:12009895, GO:0019899=PMID:12586838, GO:0060368=GO_REF:0000024, GO:0006659=GO_REF:0000024} O15162 Phospholipid scramblase 1 protein 20130415 {GO:2000373=IDA, GO:0005515=IPI, GO:0017121=IDA, GO:0005154=IPI, GO:0017124=IDA, GO:0005886=IDA, GO:0017128=IDA, GO:0035456=IMP, GO:0005634=IDA, GO:0033003=ISS, GO:0051607=IMP, GO:0042609=IPI, GO:0045944=IDA, GO:0045071=IMP, GO:0005794=IDA, GO:0005509=IDA, GO:0005730=IDA, GO:0030168=NAS, GO:0006915=IDA, GO:0006953=ISS, GO:0003677=IEA, GO:0010628=IMP, GO:0031012=IDA, GO:0001077=IDA, GO:0045089=IMP, GO:0005887=IDA, GO:0045121=IDA, GO:0019899=IPI, GO:0060368=ISS, GO:0006659=ISS} acute-phase response, apoptotic process, defense response to virus, negative regulation of viral genome replication, phosphatidylserine biosynthetic process, phospholipid scrambling, platelet activation, positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity, positive regulation of gene expression, positive regulation of innate immune response, positive regulation of transcription from RNA polymerase II promoter, regulation of Fc receptor mediated stimulatory signaling pathway, regulation of mast cell activation, response to interferon-beta Golgi apparatus, extracellular matrix, integral to plasma membrane, membrane raft, nucleolus, nucleus, plasma membrane CD4 receptor binding, DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, SH3 domain binding, calcium ion binding, enzyme binding, epidermal growth factor receptor binding, phospholipid scramblase activity, protein binding Human UniProtKB:Q92734 PLSCR2 UniProtKB UniProtKB {GO:0017121=PMID:10930526, GO:0005886=PMID:10930526, GO:0017128=PMID:10930526, GO:0005509=PMID:10930526, GO:0016021=GO_REF:0000037} Q9NRY7 Phospholipid scramblase 2 protein 20010913 {GO:0017121=NAS, GO:0005886=NAS, GO:0017128=NAS, GO:0005509=NAS, GO:0016021=IEA} phospholipid scrambling integral to membrane, plasma membrane calcium ion binding, phospholipid scramblase activity Human PLSCR3 IntAct UniProtKB {GO:0042632=GO_REF:0000019, GO:0005515=PMID:18256029, GO:0017121=PMID:10930526, GO:0017124=GO_REF:0000037, GO:0031966=GO_REF:0000039, GO:0005886=PMID:19333378, GO:0017128=PMID:10930526, GO:0005509=PMID:10930526, GO:0006915=GO_REF:0000037, GO:0042593=GO_REF:0000019, GO:0071222=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0048306=PMID:18256029} Q9NRY6 Phospholipid scramblase 3 protein 20130415 {GO:0042632=IEA, GO:0005515=IPI, GO:0017121=NAS, GO:0017124=IEA, GO:0031966=IEA, GO:0005886=IDA, GO:0017128=NAS, GO:0005509=NAS, GO:0006915=IEA, GO:0042593=IEA, GO:0071222=IEA, GO:0016021=IEA, GO:0048306=IPI} apoptotic process, cellular response to lipopolysaccharide, cholesterol homeostasis, glucose homeostasis, phospholipid scrambling integral to membrane, mitochondrial membrane, plasma membrane SH3 domain binding, calcium ion binding, calcium-dependent protein binding, phospholipid scramblase activity, protein binding Human UniProtKB:O75340 PLSCR4 UniProtKB UniProtKB {GO:0005515=PMID:18256029, GO:0017121=PMID:10930526, GO:0017124=GO_REF:0000037, GO:0042609=PMID:19333378, GO:0071222=GO_REF:0000019, GO:0005886=PMID:19333378, GO:0007596=GO_REF:0000029, GO:0017128=PMID:10930526, GO:0005509=PMID:10930526, GO:0016021=GO_REF:0000029, GO:0019899=PMID:19333378} Q9NRQ2 Phospholipid scramblase 4 protein 20110809 {GO:0005515=IPI, GO:0017121=NAS, GO:0017124=IEA, GO:0042609=IPI, GO:0071222=IEA, GO:0005886=IDA, GO:0007596=NAS, GO:0017128=NAS, GO:0005509=NAS, GO:0016021=NAS, GO:0019899=IPI} blood coagulation, cellular response to lipopolysaccharide, phospholipid scrambling integral to membrane, plasma membrane CD4 receptor binding, SH3 domain binding, calcium ion binding, enzyme binding, phospholipid scramblase activity, protein binding Human PLTP PINC UniProtKB {GO:0006629=PMID:7654777, GO:0006869=GO_REF:0000037, GO:0005576=GO_REF:0000039, GO:0030317=GO_REF:0000019, GO:0010189=GO_REF:0000019, GO:0008289=GO_REF:0000002} P55058 Phospholipid transfer protein protein 20030904 {GO:0006629=TAS, GO:0006869=IEA, GO:0005576=IEA, GO:0030317=IEA, GO:0010189=IEA, GO:0008289=IEA} lipid metabolic process, lipid transport, sperm motility, vitamin E biosynthetic process extracellular region lipid binding Human PLXDC1 UniProtKB UniProtKB {GO:0005515=PMID:15574754, GO:0005737=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0005576=GO_REF:0000039, GO:0001525=PMID:10947988, GO:0005923=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q8IUK5 Plexin domain-containing protein 1 protein 20111215 {GO:0005515=IPI, GO:0005737=IEA, GO:0005886=IEA, GO:0005576=IEA, GO:0001525=NAS, GO:0005923=IEA, GO:0016021=IEA} angiogenesis cytoplasm, extracellular region, integral to membrane, plasma membrane, tight junction protein binding Human UniProtKB:Q14247 PLXDC2 IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0016021=GO_REF:0000037} Q6UX71 Plexin domain-containing protein 2 protein 20130415 {GO:0005515=IPI, GO:0016021=IEA} integral to membrane protein binding Human UniProtKB:A2APF7 PLXNA1 HPA UniProtKB {GO:0002116=PMID:19909241, GO:0005737=GO_REF:0000052, GO:0005886=Reactome:REACT_19361, GO:0017154=PMID:10520995, GO:0007411=Reactome:REACT_18266, GO:0060666=GO_REF:0000019, GO:0004872=PMID:8570614, GO:0007275=PMID:8570614, GO:0005634=GO_REF:0000052, GO:0016021=GO_REF:0000037} Q9UIW2 Plexin-A1 protein 20080205 {GO:0002116=TAS, GO:0005737=IDA, GO:0005886=TAS, GO:0017154=TAS, GO:0007411=TAS, GO:0060666=IEA, GO:0004872=TAS, GO:0007275=TAS, GO:0005634=IDA, GO:0016021=IEA} axon guidance, dichotomous subdivision of terminal units involved in salivary gland branching, multicellular organismal development cytoplasm, integral to membrane, nucleus, plasma membrane, semaphorin receptor complex receptor activity, semaphorin receptor activity Human PLXNA2 BHF-UCL UniProtKB {GO:0005515=PMID:12372285, GO:0030334=GO_REF:0000024, GO:0021935=GO_REF:0000019, GO:0005886=Reactome:REACT_19321, GO:0001756=GO_REF:0000019, GO:0060037=GO_REF:0000019, GO:0002116=PMID:19909241, GO:0005622=GO_REF:0000002, GO:0051642=GO_REF:0000019, GO:0017154=GO_REF:0000024, GO:0005887=GO_REF:0000024, GO:0007411=Reactome:REACT_18266, GO:0021915=GO_REF:0000019, GO:0071526=GO_REF:0000024, GO:0060174=GO_REF:0000019} O75051 Plexin-A2 protein 20110907 {GO:0005515=IPI, GO:0030334=ISS, GO:0021935=IEA, GO:0005886=TAS, GO:0001756=IEA, GO:0060037=IEA, GO:0002116=TAS, GO:0005622=IEA, GO:0051642=IEA, GO:0017154=ISS, GO:0005887=ISS, GO:0007411=TAS, GO:0021915=IEA, GO:0071526=ISS, GO:0060174=IEA} axon guidance, centrosome localization, cerebellar granule cell precursor tangential migration, limb bud formation, neural tube development, pharyngeal system development, regulation of cell migration, semaphorin-plexin signaling pathway, somitogenesis integral to plasma membrane, intracellular, plasma membrane, semaphorin receptor complex protein binding, semaphorin receptor activity Human PLXNA3 BHF-UCL UniProtKB {GO:0005886=Reactome:REACT_19321, GO:0050919=GO_REF:0000019, GO:0048843=GO_REF:0000019, GO:0007275=PMID:8570614, GO:0021860=GO_REF:0000019, GO:0002116=PMID:19909241, GO:0005622=GO_REF:0000002, GO:0021766=GO_REF:0000019, GO:0017154=GO_REF:0000019, GO:0016020=PMID:8570614, GO:0007411=Reactome:REACT_18266, GO:0051495=GO_REF:0000019, GO:0071526=PMID:19909241, GO:0016021=GO_REF:0000037, GO:0004888=PMID:8570614} P51805 Plexin-A3 protein 20110907 {GO:0005886=TAS, GO:0050919=IEA, GO:0048843=IEA, GO:0007275=TAS, GO:0021860=IEA, GO:0002116=TAS, GO:0005622=IEA, GO:0021766=IEA, GO:0017154=IEA, GO:0016020=TAS, GO:0007411=TAS, GO:0051495=IEA, GO:0071526=NAS, GO:0016021=IEA, GO:0004888=NAS} axon guidance, hippocampus development, multicellular organismal development, negative chemotaxis, negative regulation of axon extension involved in axon guidance, positive regulation of cytoskeleton organization, pyramidal neuron development, semaphorin-plexin signaling pathway integral to membrane, intracellular, membrane, plasma membrane, semaphorin receptor complex semaphorin receptor activity, transmembrane signaling receptor activity Human PLXNA4 BHF-UCL UniProtKB {GO:0021960=GO_REF:0000019, GO:0005886=Reactome:REACT_19321, GO:0021644=GO_REF:0000019, GO:0048485=GO_REF:0000019, GO:0002116=PMID:19909241, GO:0005622=GO_REF:0000002, GO:0021784=GO_REF:0000019, GO:0021793=GO_REF:0000019, GO:0050923=GO_REF:0000019, GO:0021615=GO_REF:0000019, GO:0017154=GO_REF:0000019, GO:0048841=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0021636=GO_REF:0000019, GO:0071526=PMID:19909241, GO:0016021=GO_REF:0000037, GO:0021610=GO_REF:0000019} Q9HCM2 Plexin-A4 protein 20110907 {GO:0021960=IEA, GO:0005886=TAS, GO:0021644=IEA, GO:0048485=IEA, GO:0002116=TAS, GO:0005622=IEA, GO:0021784=IEA, GO:0021793=IEA, GO:0050923=IEA, GO:0021615=IEA, GO:0017154=IEA, GO:0048841=IEA, GO:0007411=TAS, GO:0021636=IEA, GO:0071526=NAS, GO:0016021=IEA, GO:0021610=IEA} anterior commissure morphogenesis, axon guidance, chemorepulsion of branchiomotor axon, facial nerve morphogenesis, glossopharyngeal nerve morphogenesis, postganglionic parasympathetic nervous system development, regulation of axon extension involved in axon guidance, regulation of negative chemotaxis, semaphorin-plexin signaling pathway, sympathetic nervous system development, trigeminal nerve morphogenesis, vagus nerve morphogenesis integral to membrane, intracellular, plasma membrane, semaphorin receptor complex semaphorin receptor activity Human PLXNB1 BHF-UCL UniProtKB {GO:0005515=PMID:22404908, GO:1900220=GO_REF:0000024, GO:0043931=GO_REF:0000024, GO:0033689=GO_REF:0000024, GO:0005886=Reactome:REACT_19398, GO:0008360=PMID:19843518, GO:0035556=PMID:10520995, GO:0005622=GO_REF:0000002, GO:0002116=PMID:19909241, GO:0017154=PMID:19843518, GO:0007411=Reactome:REACT_18266, GO:0004872=PMID:8570614, GO:0005576=GO_REF:0000039, GO:0014068=GO_REF:0000024, GO:0032794=GO_REF:0000024, GO:0007165=PMID:8570614, GO:0016477=PMID:10520995, GO:0051493=PMID:19843518, GO:0032321=GO_REF:0000024, GO:0005887=PMID:19843518, GO:0048812=GO_REF:0000024, GO:0071526=PMID:19843518, GO:0030215=PMID:10520995, GO:0050772=GO_REF:0000019, GO:0004888=PMID:10520995} O43157 Plexin-B1 protein 20111208 {GO:0005515=IPI, GO:1900220=ISS, GO:0043931=ISS, GO:0033689=ISS, GO:0005886=TAS, GO:0008360=IDA, GO:0035556=NAS, GO:0005622=IEA, GO:0002116=TAS, GO:0017154=IDA, GO:0007411=TAS, GO:0004872=TAS, GO:0005576=IEA, GO:0014068=ISS, GO:0032794=ISS, GO:0007165=TAS, GO:0016477=NAS, GO:0051493=IDA, GO:0032321=ISS, GO:0005887=IDA, GO:0048812=ISS, GO:0071526=IDA, GO:0030215=TAS, GO:0050772=IEA, GO:0004888=NAS} axon guidance, cell migration, intracellular signal transduction, negative regulation of osteoblast proliferation, neuron projection morphogenesis, ossification involved in bone maturation, positive regulation of Rho GTPase activity, positive regulation of axonogenesis, positive regulation of phosphatidylinositol 3-kinase cascade, regulation of cell shape, regulation of cytoskeleton organization, semaphorin-plexin signaling pathway, semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis, signal transduction extracellular region, integral to plasma membrane, intracellular, plasma membrane, semaphorin receptor complex GTPase activating protein binding, protein binding, receptor activity, semaphorin receptor activity, semaphorin receptor binding, transmembrane signaling receptor activity Human UniProtKB:Q8CJH3 PLXNB2 IntAct UniProtKB {GO:0005515=PMID:15184888, GO:0008360=GO_REF:0000024, GO:2001222=GO_REF:0000024, GO:0001843=GO_REF:0000024, GO:0007405=GO_REF:0000024, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0017154=GO_REF:0000024, GO:0005887=GO_REF:0000024, GO:0007420=GO_REF:0000024, GO:0071526=GO_REF:0000024, GO:0001932=GO_REF:0000024, GO:0050772=GO_REF:0000019, GO:0032319=GO_REF:0000024, GO:0005096=GO_REF:0000002} O15031 Plexin-B2 protein 20130415 {GO:0005515=IPI, GO:0008360=ISS, GO:2001222=ISS, GO:0001843=ISS, GO:0007405=ISS, GO:0005622=IEA, GO:0007165=IEA, GO:0017154=ISS, GO:0005887=ISS, GO:0007420=ISS, GO:0071526=ISS, GO:0001932=ISS, GO:0050772=IEA, GO:0032319=ISS, GO:0005096=IEA} brain development, neural tube closure, neuroblast proliferation, positive regulation of axonogenesis, regulation of Rho GTPase activity, regulation of cell shape, regulation of neuron migration, regulation of protein phosphorylation, semaphorin-plexin signaling pathway, signal transduction integral to plasma membrane, intracellular GTPase activator activity, protein binding, semaphorin receptor activity Human UniProtKB:Q04912 PLXNB3 IntAct UniProtKB {GO:0005515=PMID:21706053, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0005886=Reactome:REACT_19322, GO:0007411=Reactome:REACT_18266, GO:0007275=GO_REF:0000002, GO:0004872=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q9ULL4 Plexin-B3 protein 20130415 {GO:0005515=IPI, GO:0005622=IEA, GO:0007165=IEA, GO:0005886=TAS, GO:0007411=TAS, GO:0007275=IEA, GO:0004872=IEA, GO:0016021=IEA} axon guidance, multicellular organismal development, signal transduction integral to membrane, intracellular, plasma membrane protein binding, receptor activity Human UniProtKB:Q16658 PLXNC1 IntAct UniProtKB {GO:0005515=PMID:20727575, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0005886=Reactome:REACT_19190, GO:0007411=Reactome:REACT_18266, GO:0005102=PMID:9586637, GO:0007275=GO_REF:0000002, GO:0004872=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007155=PMID:9586637} O60486 Plexin-C1 protein 20130415 {GO:0005515=IPI, GO:0005622=IEA, GO:0007165=IEA, GO:0005886=TAS, GO:0007411=TAS, GO:0005102=TAS, GO:0007275=IEA, GO:0004872=IEA, GO:0016021=IEA, GO:0007155=TAS} axon guidance, cell adhesion, multicellular organismal development, signal transduction integral to membrane, intracellular, plasma membrane protein binding, receptor activity, receptor binding Human UniProtKB:Q8JL80 PLXND1 Reactome UniProtKB {GO:0030334=GO_REF:0000024, GO:0001569=GO_REF:0000019, GO:0005886=Reactome:REACT_19408, GO:0045765=GO_REF:0000024, GO:0007275=GO_REF:0000002, GO:0001525=GO_REF:0000024, GO:0007416=GO_REF:0000024, GO:0005622=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0017154=GO_REF:0000024, GO:0007411=Reactome:REACT_18266, GO:0005887=GO_REF:0000024, GO:0043542=GO_REF:0000024, GO:0060666=GO_REF:0000019, GO:0071526=GO_REF:0000024, GO:0004872=GO_REF:0000002, GO:0016021=GO_REF:0000038} Q9Y4D7 Plexin-D1 protein 20071230 {GO:0030334=ISS, GO:0001569=IEA, GO:0005886=TAS, GO:0045765=ISS, GO:0007275=IEA, GO:0001525=ISS, GO:0007416=ISS, GO:0005622=IEA, GO:0007165=IEA, GO:0017154=ISS, GO:0007411=TAS, GO:0005887=ISS, GO:0043542=ISS, GO:0060666=IEA, GO:0071526=ISS, GO:0004872=IEA, GO:0016021=IEA} angiogenesis, axon guidance, dichotomous subdivision of terminal units involved in salivary gland branching, endothelial cell migration, multicellular organismal development, patterning of blood vessels, regulation of angiogenesis, regulation of cell migration, semaphorin-plexin signaling pathway, signal transduction, synapse assembly integral to membrane, integral to plasma membrane, intracellular, plasma membrane receptor activity, semaphorin receptor activity Human PM20D2 InterPro UniProtKB {GO:0016787=GO_REF:0000002} Q8IYS1 Peptidase M20 domain-containing protein 2 protein 20130413 {GO:0016787=IEA} hydrolase activity Human InterPro:IPR002933 PMAIP1 IntAct UniProtKB {GO:0005515=PMID:21454712, GO:0043331=PMID:15705586, GO:0010165=GO_REF:0000019, GO:0048147=GO_REF:0000019, GO:0005741=Reactome:REACT_21278, GO:0001836=GO_REF:0000019, GO:0005634=PMID:12879012, GO:0006926=PMID:15705586, GO:0006921=PMID:15705586, GO:0010907=PMID:21145489, GO:0005829=Reactome:REACT_2201, GO:0005739=PMID:15705586, GO:1900740=Reactome:REACT_1194, GO:0043525=GO_REF:0000019, GO:0090200=PMID:14699081, GO:0042149=PMID:21145489, GO:0032461=PMID:17024184, GO:0043029=GO_REF:0000024, GO:0009411=GO_REF:0000019, GO:0046902=PMID:14500711, GO:0043065=PMID:21525171, GO:0006919=PMID:15705586, GO:0072593=PMID:14699081, GO:0006915=Reactome:REACT_578, GO:0071456=PMID:20810912, GO:2001244=Reactome:REACT_330, GO:0006917=PMID:15705586, GO:0097193=Reactome:REACT_964, GO:0006974=GO_REF:0000019, GO:0043280=PMID:14699081, GO:0010917=PMID:14699081, GO:0072332=PMID:15102863, GO:0043517=PMID:15102863, GO:0010498=PMID:15901672} Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 protein 20130415 {GO:0005515=IPI, GO:0043331=IDA, GO:0010165=IEA, GO:0048147=IEA, GO:0005741=TAS, GO:0001836=IEA, GO:0005634=IDA, GO:0006926=IDA, GO:0006921=IDA, GO:0010907=IDA, GO:0005829=TAS, GO:0005739=IDA, GO:1900740=TAS, GO:0043525=IEA, GO:0090200=IDA, GO:0042149=IMP, GO:0032461=IDA, GO:0043029=ISS, GO:0009411=IEA, GO:0046902=IDA, GO:0043065=IMP, GO:0006919=IDA, GO:0072593=IDA, GO:0006915=TAS, GO:0071456=IEP, GO:2001244=TAS, GO:0006917=IDA, GO:0097193=TAS, GO:0006974=IEA, GO:0043280=IDA, GO:0010917=ISS, GO:0072332=IMP, GO:0043517=IMP, GO:0010498=IDA} T cell homeostasis, activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, cellular component disassembly involved in execution phase of apoptosis, cellular response to glucose starvation, cellular response to hypoxia, induction of apoptosis, intrinsic apoptotic signaling pathway, intrinsic apoptotic signaling pathway by p53 class mediator, negative regulation of fibroblast proliferation, negative regulation of mitochondrial membrane potential, positive regulation of DNA damage response, signal transduction by p53 class mediator, positive regulation of apoptotic process, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of glucose metabolic process, positive regulation of intrinsic apoptotic signaling pathway, positive regulation of neuron apoptotic process, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, positive regulation of protein oligomerization, positive regulation of release of cytochrome c from mitochondria, proteasomal protein catabolic process, reactive oxygen species metabolic process, regulation of mitochondrial membrane permeability, release of cytochrome c from mitochondria, response to DNA damage stimulus, response to UV, response to X-ray, response to dsRNA, virus-infected cell apoptotic process cytosol, mitochondrial outer membrane, mitochondrion, nucleus protein binding Human UniProtKB:P10415-1 PMCH Reactome UniProtKB {GO:0007165=PMID:1572663, GO:0007631=GO_REF:0000024, GO:0007218=GO_REF:0000037, GO:0030354=GO_REF:0000002, GO:0007610=PMID:8326825, GO:0007268=GO_REF:0000002, GO:0005576=Reactome:REACT_25247, GO:0005634=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000029, GO:0030154=GO_REF:0000037} P20382 Pro-MCH protein 20100910 {GO:0007165=NAS, GO:0007631=ISS, GO:0007218=IEA, GO:0030354=IEA, GO:0007610=NAS, GO:0007268=IEA, GO:0005576=TAS, GO:0005634=IEA, GO:0007275=IEA, GO:0007283=NAS, GO:0030154=IEA} behavior, cell differentiation, feeding behavior, multicellular organismal development, neuropeptide signaling pathway, signal transduction, spermatogenesis, synaptic transmission extracellular region, nucleus melanin-concentrating hormone activity Human PMEL PINC UniProtKB {GO:0005515=PMID:15695812, GO:0042470=PMID:15695812, GO:0005794=PMID:15695812, GO:0005886=PMID:8179825, GO:0042438=GO_REF:0000019, GO:0032438=PMID:11694580, GO:0005789=PMID:15695812, GO:0032585=PMID:11694580, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037} P40967 Melanocyte protein PMEL protein 20030904 {GO:0005515=IPI, GO:0042470=IDA, GO:0005794=IDA, GO:0005886=TAS, GO:0042438=IEA, GO:0032438=IDA, GO:0005789=IDA, GO:0032585=IDA, GO:0005576=IEA, GO:0016021=IEA} melanin biosynthetic process, melanosome organization Golgi apparatus, endoplasmic reticulum membrane, extracellular region, integral to membrane, melanosome, multivesicular body membrane, plasma membrane protein binding Human PMEPA1 Reactome UniProtKB {GO:0005886=Reactome:REACT_121239, GO:0031901=Reactome:REACT_120812, GO:0050699=PMID:12907594, GO:0007179=Reactome:REACT_120850, GO:0016021=PMID:10873380, GO:0030512=Reactome:REACT_120727, GO:0030521=PMID:10873380} Q969W9 Transmembrane prostate androgen-induced protein protein 20120409 {GO:0005886=TAS, GO:0031901=TAS, GO:0050699=IPI, GO:0007179=TAS, GO:0016021=NAS, GO:0030512=TAS, GO:0030521=NAS} androgen receptor signaling pathway, negative regulation of transforming growth factor beta receptor signaling pathway, transforming growth factor beta receptor signaling pathway early endosome membrane, integral to membrane, plasma membrane WW domain binding Human PMF1 Reactome UniProtKB {GO:0005515=PMID:15502821, GO:0005667=PMID:10419538, GO:0000236=Reactome:REACT_682, GO:0006355=GO_REF:0000037, GO:0006366=PMID:10419538, GO:0003713=PMID:11256947, GO:0005829=Reactome:REACT_150414, GO:0043522=PMID:11256947, GO:0007059=PMID:15502821, GO:0000087=Reactome:REACT_910, GO:0000444=PMID:16585270, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q6P1K2 Polyamine-modulated factor 1 protein 20130213 {GO:0005515=IPI, GO:0005667=TAS, GO:0000236=TAS, GO:0006355=IEA, GO:0006366=TAS, GO:0003713=IMP, GO:0005829=TAS, GO:0043522=IPI, GO:0007059=IMP, GO:0000087=TAS, GO:0000444=IDA, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, cell division, chromosome segregation, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter MIS12/MIND type complex, cytosol, transcription factor complex leucine zipper domain binding, protein binding, transcription coactivator activity Human PML HPA UniProtKB {GO:0005515=PMID:12006491, GO:0051974=PMID:19567472, GO:0030308=PMID:9448006, GO:0010522=GO_REF:0000024, GO:0019221=Reactome:REACT_25229, GO:0046332=GO_REF:0000019, GO:0042803=PMID:9230084, GO:0005622=GO_REF:0000002, GO:0051607=GO_REF:0000037, GO:0032211=PMID:19567472, GO:0030578=PMID:17081985, GO:0030099=GO_REF:0000019, GO:0007179=GO_REF:0000019, GO:0010332=GO_REF:0000019, GO:0009411=GO_REF:0000019, GO:0031625=PMID:12915590, GO:0060333=Reactome:REACT_25078, GO:0006977=GO_REF:0000024, GO:0031965=PMID:123456, GO:0032469=GO_REF:0000024, GO:0048384=GO_REF:0000019, GO:0007182=GO_REF:0000019, GO:0042771=GO_REF:0000024, GO:0045165=GO_REF:0000019, GO:0051457=PMID:17332504, GO:0007184=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_25082, GO:0042406=GO_REF:0000024, GO:0045892=PMID:9448006, GO:0060444=GO_REF:0000019, GO:0090398=PMID:22117195, GO:2001238=PMID:21803845, GO:0008285=PMID:12006491, GO:0005634=GO_REF:0000052, GO:0016363=GO_REF:0000019, GO:0005829=GO_REF:0000024, GO:0005737=PMID:18298799, GO:2000779=PMID:21639834, GO:0007050=GO_REF:0000019, GO:0034097=PMID:9412458, GO:0001666=PMID:16915281, GO:0032183=PMID:17081985, GO:0006355=PMID:23007646, GO:0006919=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0006917=GO_REF:0000019, GO:0045343=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:2000059=PMID:15195100, GO:0006351=GO_REF:0000037, GO:0006461=PMID:12915590, GO:0019048=GO_REF:0000037, GO:0031901=GO_REF:0000039, GO:0016605=PMID:9412458, GO:0016525=PMID:16915281, GO:0001932=GO_REF:0000024, GO:0043161=PMID:22406621} P29590 Protein PML protein 20101115 {GO:0005515=IPI, GO:0051974=IMP, GO:0030308=IDA, GO:0010522=ISS, GO:0019221=TAS, GO:0046332=IEA, GO:0042803=IPI, GO:0005622=IEA, GO:0051607=IEA, GO:0032211=IMP, GO:0030578=IMP, GO:0030099=IEA, GO:0007179=IEA, GO:0010332=IEA, GO:0009411=IEA, GO:0031625=IPI, GO:0060333=TAS, GO:0006977=ISS, GO:0031965=IDA, GO:0032469=ISS, GO:0048384=IEA, GO:0007182=IEA, GO:0042771=ISS, GO:0045165=IEA, GO:0051457=IDA, GO:0007184=IEA, GO:0008270=IEA, GO:0005654=TAS, GO:0042406=ISS, GO:0045892=IDA, GO:0060444=IEA, GO:0090398=IDA, GO:2001238=IMP, GO:0008285=IMP, GO:0005634=IDA, GO:0016363=IEA, GO:0005829=ISS, GO:0005737=IDA, GO:2000779=IMP, GO:0007050=IEA, GO:0034097=IDA, GO:0001666=IDA, GO:0032183=IPI, GO:0006355=IMP, GO:0006919=IEA, GO:0005730=IDA, GO:0006917=IEA, GO:0045343=IEA, GO:0003677=IEA, GO:2000059=IMP, GO:0006351=IEA, GO:0006461=IDA, GO:0019048=IEA, GO:0031901=IEA, GO:0016605=IDA, GO:0016525=IMP, GO:0001932=ISS, GO:0043161=IDA} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, PML body organization, SMAD protein import into nucleus, activation of cysteine-type endopeptidase activity involved in apoptotic process, branching involved in mammary gland duct morphogenesis, cell cycle arrest, cell fate commitment, cellular senescence, common-partner SMAD protein phosphorylation, cytokine-mediated signaling pathway, defense response to virus, endoplasmic reticulum calcium ion homeostasis, induction of apoptosis, interferon-gamma-mediated signaling pathway, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, maintenance of protein location in nucleus, myeloid cell differentiation, negative regulation of angiogenesis, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process, negative regulation of telomerase activity, negative regulation of telomere maintenance via telomerase, negative regulation of transcription, DNA-dependent, positive regulation of extrinsic apoptotic signaling pathway, proteasomal ubiquitin-dependent protein catabolic process, protein complex assembly, regulation of MHC class I biosynthetic process, regulation of calcium ion transport into cytosol, regulation of double-strand break repair, regulation of protein phosphorylation, regulation of transcription, DNA-dependent, response to UV, response to cytokine stimulus, response to gamma radiation, response to hypoxia, retinoic acid receptor signaling pathway, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, virus-host interaction PML body, cytoplasm, cytosol, early endosome membrane, extrinsic to endoplasmic reticulum membrane, intracellular, nuclear matrix, nuclear membrane, nucleolus, nucleoplasm, nucleus DNA binding, SMAD binding, SUMO binding, protein binding, protein homodimerization activity, ubiquitin protein ligase binding, zinc ion binding NOT Human PMM1 Reactome UniProtKB {GO:0004615=GO_REF:0000003, GO:0005737=GO_REF:0000002, GO:0043025=GO_REF:0000019, GO:0019307=GO_REF:0000002, GO:0009298=Reactome:REACT_22423, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0046872=GO_REF:0000037, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426, GO:0005829=Reactome:REACT_22437, GO:0006013=PMID:9070917} Q92871 Phosphomannomutase 1 protein 20130301 {GO:0004615=IEA, GO:0005737=IEA, GO:0043025=IEA, GO:0019307=IEA, GO:0009298=TAS, GO:0006488=TAS, GO:0044267=TAS, GO:0046872=IEA, GO:0043687=TAS, GO:0018279=TAS, GO:0005829=TAS, GO:0006013=TAS} GDP-mannose biosynthetic process, cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, mannose biosynthetic process, mannose metabolic process, post-translational protein modification, protein N-linked glycosylation via asparagine cytoplasm, cytosol, neuronal cell body metal ion binding, phosphomannomutase activity Human PMM2 Reactome UniProtKB {GO:0004615=GO_REF:0000003, GO:0005737=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0019307=GO_REF:0000002, GO:0006486=PMID:9140401, GO:0009298=Reactome:REACT_22423, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426, GO:0005829=Reactome:REACT_22437} O15305 Phosphomannomutase 2 protein 20130301 {GO:0004615=IEA, GO:0005737=IEA, GO:0043025=IEA, GO:0019307=IEA, GO:0006486=TAS, GO:0009298=TAS, GO:0006488=TAS, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS, GO:0005829=TAS} GDP-mannose biosynthetic process, cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, mannose biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine, protein glycosylation cytoplasm, cytosol, neuronal cell body phosphomannomutase activity Human PMP22 UniProtKB UniProtKB {GO:0005515=PMID:14709540, GO:0008285=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0043218=GO_REF:0000019, GO:0007422=PMID:8275092, GO:0010977=GO_REF:0000019, GO:0007268=PMID:8275092, GO:0005923=GO_REF:0000019, GO:0016021=GO_REF:0000019, GO:0032288=GO_REF:0000019} Q01453 Peripheral myelin protein 22 protein 20120708 {GO:0005515=IPI, GO:0008285=IEA, GO:0005886=IEA, GO:0043218=IEA, GO:0007422=TAS, GO:0010977=IEA, GO:0007268=TAS, GO:0005923=IEA, GO:0016021=IEA, GO:0032288=IEA} myelin assembly, negative regulation of cell proliferation, negative regulation of neuron projection development, peripheral nervous system development, synaptic transmission compact myelin, integral to membrane, plasma membrane, tight junction protein binding Human UniProtKB:P40855 PMPCA InterPro UniProtKB {GO:0005739=GO_REF:0000019, GO:0005759=GO_REF:0000039, GO:0006626=Reactome:REACT_118595, GO:0006508=GO_REF:0000002, GO:0005743=PMID:10942759, GO:0004222=GO_REF:0000002, GO:0003824=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0046872=GO_REF:0000002} Q5SXN9 Mitochondrial-processing peptidase subunit alpha protein 20130413 {GO:0005739=IEA, GO:0005759=IEA, GO:0006626=TAS, GO:0006508=IEA, GO:0005743=TAS, GO:0004222=IEA, GO:0003824=IEA, GO:0044267=TAS, GO:0046872=IEA} cellular protein metabolic process, protein targeting to mitochondrion, proteolysis mitochondrial inner membrane, mitochondrial matrix, mitochondrion catalytic activity, metal ion binding, metalloendopeptidase activity Human InterPro:IPR011237|InterPro:IPR011249 PMPCB Reactome UniProtKB {GO:0005759=GO_REF:0000039, GO:0006626=Reactome:REACT_118595, GO:0005743=GO_REF:0000019, GO:0006508=GO_REF:0000037, GO:0004222=GO_REF:0000002, GO:0003824=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0046872=GO_REF:0000037} O75439 Mitochondrial-processing peptidase subunit beta protein 20110523 {GO:0005759=IEA, GO:0006626=TAS, GO:0005743=IEA, GO:0006508=IEA, GO:0004222=IEA, GO:0003824=IEA, GO:0044267=TAS, GO:0046872=IEA} cellular protein metabolic process, protein targeting to mitochondrion, proteolysis mitochondrial inner membrane, mitochondrial matrix catalytic activity, metal ion binding, metalloendopeptidase activity Human PMS1 InterPro UniProtKB {GO:0032407=GO_REF:0000033, GO:0032389=GO_REF:0000033, GO:0032300=GO_REF:0000033, GO:0030983=GO_REF:0000002, GO:0006200=GO_REF:0000033, GO:0003697=GO_REF:0000033, GO:0005634=PMID:8072530, GO:0006298=GO_REF:0000002, GO:0003677=PMID:8072530, GO:0016887=GO_REF:0000033, GO:0005524=GO_REF:0000002, GO:0007131=GO_REF:0000033} Q5XG96 PMS1 protein homolog 1 protein 20130413 {GO:0032407=IBA, GO:0032389=IBA, GO:0032300=IBA, GO:0030983=IEA, GO:0006200=IBA, GO:0003697=IBA, GO:0005634=TAS, GO:0006298=IEA, GO:0003677=TAS, GO:0016887=IBA, GO:0005524=IEA, GO:0007131=IBA} ATP catabolic process, mismatch repair, reciprocal meiotic recombination MutLalpha complex, mismatch repair complex, nucleus ATP binding, ATPase activity, DNA binding, MutSalpha complex binding, mismatched DNA binding, single-stranded DNA binding Human InterPro:IPR002099 PMS2 GOC UniProtKB {GO:0005515=PMID:20706999, GO:0032407=PMID:16403449, GO:0032389=GO_REF:0000033, GO:0030983=GO_REF:0000002, GO:0006200=GO_REF:0000033, GO:0042493=GO_REF:0000019, GO:0005634=PMID:10871409, GO:0016446=GO_REF:0000033, GO:0005524=GO_REF:0000002, GO:0003677=PMID:10871409, GO:0032300=GO_REF:0000033, GO:0004519=GO_REF:0000037, GO:0003697=PMID:11809883, GO:0032138=PMID:10871409, GO:0016447=GO_REF:0000019, GO:0006298=PMID:10871409, GO:0016887=GO_REF:0000033, GO:0007131=GO_REF:0000033} P54278 Mismatch repair endonuclease PMS2 protein 20130413 {GO:0005515=IPI, GO:0032407=IDA, GO:0032389=IBA, GO:0030983=IEA, GO:0006200=IBA, GO:0042493=IEA, GO:0005634=IC, GO:0016446=IBA, GO:0005524=IEA, GO:0003677=IDA, GO:0032300=IBA, GO:0004519=IEA, GO:0003697=IDA, GO:0032138=IDA, GO:0016447=IEA, GO:0006298=IDA, GO:0016887=IBA, GO:0007131=IBA} ATP catabolic process, mismatch repair, reciprocal meiotic recombination, response to drug, somatic hypermutation of immunoglobulin genes, somatic recombination of immunoglobulin gene segments MutLalpha complex, mismatch repair complex, nucleus ATP binding, ATPase activity, DNA binding, MutSalpha complex binding, endonuclease activity, mismatched DNA binding, protein binding, single base insertion or deletion binding, single-stranded DNA binding Human PANTHER:PTN000008161 PMVK Reactome UniProtKB {GO:0006695=Reactome:REACT_9405, GO:0016126=PMID:16519518, GO:0070723=PMID:10191291, GO:0004631=PMID:16519518, GO:0019287=GO_REF:0000041, GO:0044281=Reactome:REACT_111217, GO:0005524=PMID:16519518, GO:0005829=Reactome:REACT_147771, GO:0005777=PMID:17180682} Q15126 Phosphomevalonate kinase protein 20130301 {GO:0006695=TAS, GO:0016126=IDA, GO:0070723=IEP, GO:0004631=IDA, GO:0019287=IEA, GO:0044281=TAS, GO:0005524=IDA, GO:0005829=TAS, GO:0005777=IDA} cholesterol biosynthetic process, isopentenyl diphosphate biosynthetic process, mevalonate pathway, response to cholesterol, small molecule metabolic process, sterol biosynthetic process cytosol, peroxisome ATP binding, phosphomevalonate kinase activity Human PNISR UniProtKB UniProtKB {GO:0016607=GO_REF:0000039} Q8TF01 Arginine/serine-rich protein PNISR protein 20130413 {GO:0016607=IEA} nuclear speck Human UniProtKB-SubCell:SL-0186 PNKD HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0016020=GO_REF:0000039, GO:0006750=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0004416=GO_REF:0000002} Q8N490 Probable hydrolase PNKD protein 20080205 {GO:0005739=IDA, GO:0016020=IEA, GO:0006750=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0004416=IEA} glutathione biosynthetic process membrane, mitochondrion, nucleus hydroxyacylglutathione hydrolase activity, zinc ion binding Human PNKP HPA UniProtKB {GO:0009314=PMID:10446192, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0019201=PMID:10446192, GO:0005524=PMID:10446192, GO:0003684=PMID:10446193, GO:0006261=PMID:10446192, GO:0046404=PMID:10446193, GO:0004519=PMID:10446192, GO:0006281=PMID:10446192, GO:0003690=PMID:10446193, GO:0042769=PMID:10446192, GO:0046403=PMID:10446192, GO:0016311=PMID:10446193, GO:0046939=PMID:10446193, GO:0017076=PMID:10446193, GO:0000718=PMID:10446193, GO:0006979=PMID:10446192} Q96T60 Bifunctional polynucleotide phosphatase/kinase protein 20080205 {GO:0009314=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0019201=IDA, GO:0005524=NAS, GO:0003684=NAS, GO:0006261=NAS, GO:0046404=IDA, GO:0004519=NAS, GO:0006281=IGI, GO:0003690=TAS, GO:0042769=IDA, GO:0046403=IDA, GO:0016311=IDA, GO:0046939=IDA, GO:0017076=NAS, GO:0000718=NAS, GO:0006979=IDA} DNA damage response, detection of DNA damage, DNA repair, DNA-dependent DNA replication, dephosphorylation, nucleotide phosphorylation, nucleotide-excision repair, DNA damage removal, response to oxidative stress, response to radiation nucleolus, nucleus ATP binding, ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity, damaged DNA binding, double-stranded DNA binding, endonuclease activity, nucleotide kinase activity, polynucleotide 3'-phosphatase activity, purine nucleotide binding NOT Human PNLIP Reactome UniProtKB {GO:0006629=Reactome:REACT_602, GO:0030299=GO_REF:0000019, GO:0016042=GO_REF:0000037, GO:0004806=GO_REF:0000003, GO:0007603=Reactome:REACT_160125, GO:0044241=Reactome:REACT_9518, GO:0005576=Reactome:REACT_25240, GO:0044281=Reactome:REACT_111217, GO:0050253=GO_REF:0000003, GO:0001523=Reactome:REACT_24968, GO:0046872=GO_REF:0000037} P16233 Pancreatic triacylglycerol lipase protein 20070202 {GO:0006629=TAS, GO:0030299=IEA, GO:0016042=IEA, GO:0004806=IEA, GO:0007603=TAS, GO:0044241=TAS, GO:0005576=TAS, GO:0044281=TAS, GO:0050253=IEA, GO:0001523=TAS, GO:0046872=IEA} intestinal cholesterol absorption, lipid catabolic process, lipid digestion, lipid metabolic process, phototransduction, visible light, retinoid metabolic process, small molecule metabolic process extracellular region metal ion binding, retinyl-palmitate esterase activity, triglyceride lipase activity Human PNLIPRP2 Reactome UniProtKB {GO:0006629=Reactome:REACT_602, GO:0004806=GO_REF:0000003, GO:0044241=Reactome:REACT_9518, GO:0005509=PMID:18702514, GO:0005576=Reactome:REACT_9389, GO:0044281=Reactome:REACT_111217, GO:0050253=GO_REF:0000003, GO:0004620=PMID:18702514, GO:0019376=PMID:18702514, GO:0005615=PMID:18702514, GO:0047714=PMID:18702514, GO:0047372=PMID:18702514, GO:0006641=PMID:1379598, GO:0009395=PMID:18702514} P54317 Pancreatic lipase-related protein 2 protein 20130301 {GO:0006629=TAS, GO:0004806=IEA, GO:0044241=TAS, GO:0005509=IDA, GO:0005576=TAS, GO:0044281=TAS, GO:0050253=IEA, GO:0004620=IDA, GO:0019376=IDA, GO:0005615=IDA, GO:0047714=IDA, GO:0047372=IDA, GO:0006641=TAS, GO:0009395=IDA} galactolipid catabolic process, lipid digestion, lipid metabolic process, phospholipid catabolic process, small molecule metabolic process, triglyceride metabolic process extracellular region, extracellular space acylglycerol lipase activity, calcium ion binding, galactolipase activity, phospholipase activity, retinyl-palmitate esterase activity, triglyceride lipase activity Human PNMA1 HPA UniProtKB {GO:0005515=PMID:14676191, GO:0002437=PMID:15201193, GO:0005737=GO_REF:0000052, GO:0005730=PMID:10050892, GO:0006915=PMID:16214224, GO:0007283=PMID:10050892, GO:0007417=PMID:10050892, GO:0005925=GO_REF:0000052} Q8ND90 Paraneoplastic antigen Ma1 protein 20100326 {GO:0005515=IPI, GO:0002437=ISS, GO:0005737=IDA, GO:0005730=IDA, GO:0006915=NAS, GO:0007283=NAS, GO:0007417=NAS, GO:0005925=IDA} apoptotic process, central nervous system development, inflammatory response to antigenic stimulus, spermatogenesis cytoplasm, focal adhesion, nucleolus protein binding Human PNMA2 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0005730=GO_REF:0000039, GO:0006915=PMID:16214224} Q9UL42 Paraneoplastic antigen Ma2 protein 20130415 {GO:0005515=IPI, GO:0005730=IEA, GO:0006915=NAS} apoptotic process nucleolus protein binding Human UniProtKB:P16333 PNMA3 UniProtKB UniProtKB {GO:0005730=GO_REF:0000039, GO:0006915=PMID:16214224, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q9UL41 Paraneoplastic antigen Ma3 protein 20110131 {GO:0005730=IEA, GO:0006915=NAS, GO:0008270=IEA, GO:0003676=IEA} apoptotic process nucleolus nucleic acid binding, zinc ion binding Human PNMA6A null null {} null null null null {} null null null PNMA6B LIFEdb UniProtKB {GO:0005737=GO_REF:0000054} P0C5W0 Paraneoplastic antigen-like protein 6B protein 20100607 {GO:0005737=IDA} cytoplasm Human PNMAL1 null null {} null null null null {} null null null PNMT Reactome UniProtKB {GO:0034641=Reactome:REACT_13, GO:0004603=GO_REF:0000003, GO:0042418=GO_REF:0000041, GO:0008168=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0042423=Reactome:REACT_15551, GO:0005829=Reactome:REACT_15442} P11086 Phenylethanolamine N-methyltransferase protein 20130301 {GO:0034641=TAS, GO:0004603=IEA, GO:0042418=IEA, GO:0008168=IEA, GO:0044281=TAS, GO:0042423=TAS, GO:0005829=TAS} catecholamine biosynthetic process, cellular nitrogen compound metabolic process, epinephrine biosynthetic process, small molecule metabolic process cytosol methyltransferase activity, phenylethanolamine N-methyltransferase activity Human PNN HPA UniProtKB {GO:0030057=GO_REF:0000039, GO:0005882=PMID:10809736, GO:0006355=GO_REF:0000037, GO:0005886=PMID:8922384, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0071013=PMID:11991638, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0005737=GO_REF:0000019, GO:0016607=GO_REF:0000039, GO:0005198=PMID:8922384, GO:0005911=PMID:8922384, GO:0000398=PMID:11991638, GO:0007155=PMID:8922384} Q9H307 Pinin protein 20080205 {GO:0030057=IEA, GO:0005882=TAS, GO:0006355=IEA, GO:0005886=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0071013=IDA, GO:0003677=IEA, GO:0006351=IEA, GO:0005737=IEA, GO:0016607=IEA, GO:0005198=NAS, GO:0005911=TAS, GO:0000398=IC, GO:0007155=TAS} cell adhesion, mRNA splicing, via spliceosome, regulation of transcription, DNA-dependent, transcription, DNA-dependent catalytic step 2 spliceosome, cell-cell junction, cytoplasm, desmosome, intermediate filament, nuclear speck, nucleolus, nucleus, plasma membrane DNA binding, structural molecule activity NOT Human PNO1 UniProtKB UniProtKB {GO:0003723=GO_REF:0000037, GO:0005730=PMID:15497447} Q9NRX1 RNA-binding protein PNO1 protein 20070123 {GO:0003723=IEA, GO:0005730=IDA} nucleolus RNA binding Human PNOC Reactome UniProtKB {GO:0007165=PMID:9521323, GO:0001515=GO_REF:0000037, GO:0007218=GO_REF:0000019, GO:0007268=GO_REF:0000019, GO:0005576=Reactome:REACT_22289, GO:0005184=PMID:10419552, GO:0007600=PMID:9521323} Q13519 Prepronociceptin protein 20080730 {GO:0007165=TAS, GO:0001515=IEA, GO:0007218=IEA, GO:0007268=IEA, GO:0005576=TAS, GO:0005184=TAS, GO:0007600=TAS} neuropeptide signaling pathway, sensory perception, signal transduction, synaptic transmission extracellular region neuropeptide hormone activity, opioid peptide activity Human PNP Reactome UniProtKB {GO:0046638=PMID:16964310, GO:0004731=Reactome:REACT_1636, GO:0034356=PMID:19001417, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0005829=Reactome:REACT_1636, GO:0005622=PMID:15047506, GO:0005737=PMID:16930574, GO:0006955=PMID:16930574, GO:0006195=Reactome:REACT_2086, GO:0001882=PMID:9305962, GO:0008144=PMID:18938130, GO:0042102=PMID:16964310, GO:0043101=Reactome:REACT_1923, GO:0002060=PMID:9305962, GO:0005856=GO_REF:0000039, GO:0070970=PMID:16930574, GO:0042493=PMID:18938130, GO:0055086=Reactome:REACT_1698, GO:0006738=PMID:19001417, GO:0034418=PMID:16964310, GO:0006148=PMID:16964310, GO:0006139=PMID:3029074, GO:0006144=Reactome:REACT_522, GO:0042301=PMID:18938130, GO:0009116=GO_REF:0000002} P00491 Purine nucleoside phosphorylase protein 20100201 {GO:0046638=IDA, GO:0004731=EXP, GO:0034356=IGI, GO:0044281=TAS, GO:0003824=IEA, GO:0005829=TAS, GO:0005622=IDA, GO:0005737=IDA, GO:0006955=IMP, GO:0006195=TAS, GO:0001882=IDA, GO:0008144=IDA, GO:0042102=IDA, GO:0043101=TAS, GO:0002060=IDA, GO:0005856=IEA, GO:0070970=IMP, GO:0042493=IDA, GO:0055086=TAS, GO:0006738=IDA, GO:0034418=IDA, GO:0006148=IDA, GO:0006139=IDA, GO:0006144=TAS, GO:0042301=IDA, GO:0009116=IEA} NAD biosynthesis via nicotinamide riboside salvage pathway, immune response, inosine catabolic process, interleukin-2 secretion, nicotinamide riboside catabolic process, nucleobase-containing compound metabolic process, nucleobase-containing small molecule metabolic process, nucleoside metabolic process, positive regulation of T cell proliferation, positive regulation of alpha-beta T cell differentiation, purine nucleobase metabolic process, purine nucleotide catabolic process, purine-containing compound salvage, response to drug, small molecule metabolic process, urate biosynthetic process cytoplasm, cytoskeleton, cytosol, intracellular catalytic activity, drug binding, nucleoside binding, phosphate ion binding, purine nucleobase binding, purine-nucleoside phosphorylase activity Human PNPLA2 Reactome UniProtKB {GO:0005811=GO_REF:0000039, GO:0004806=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0010898=PMID:16679289, GO:0050253=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0005829=GO_REF:0000019, GO:0010891=PMID:16679289, GO:0005789=Reactome:REACT_121195, GO:0036155=Reactome:REACT_121122, GO:0016021=GO_REF:0000037, GO:0019433=GO_REF:0000041, GO:0006644=Reactome:REACT_120870, GO:0046474=Reactome:REACT_121401} Q96AD5 Patatin-like phospholipase domain-containing protein 2 protein 20130301 {GO:0005811=IEA, GO:0004806=ISS, GO:0005886=IEA, GO:0010898=IDA, GO:0050253=IEA, GO:0044281=TAS, GO:0005829=IEA, GO:0010891=IDA, GO:0005789=TAS, GO:0036155=TAS, GO:0016021=IEA, GO:0019433=IEA, GO:0006644=TAS, GO:0046474=TAS} acylglycerol acyl-chain remodeling, glycerophospholipid biosynthetic process, negative regulation of sequestering of triglyceride, phospholipid metabolic process, positive regulation of triglyceride catabolic process, small molecule metabolic process, triglyceride catabolic process cytosol, endoplasmic reticulum membrane, integral to membrane, lipid particle, plasma membrane retinyl-palmitate esterase activity, triglyceride lipase activity Human PNPLA3 Reactome UniProtKB {GO:0051265=PMID:15364929, GO:0051264=PMID:15364929, GO:0004806=PMID:15364929, GO:0044281=Reactome:REACT_111217, GO:0050253=GO_REF:0000003, GO:0016020=GO_REF:0000024, GO:0008152=GO_REF:0000002, GO:0004623=PMID:15364929, GO:0019432=PMID:15364929, GO:0005789=Reactome:REACT_121195, GO:0036155=Reactome:REACT_121122, GO:0016021=GO_REF:0000037, GO:0019433=PMID:15364929, GO:0006644=Reactome:REACT_120870, GO:0046474=Reactome:REACT_121401} Q9NST1 Patatin-like phospholipase domain-containing protein 3 protein 20130301 {GO:0051265=IDA, GO:0051264=IDA, GO:0004806=IDA, GO:0044281=TAS, GO:0050253=IEA, GO:0016020=ISS, GO:0008152=IEA, GO:0004623=IDA, GO:0019432=IDA, GO:0005789=TAS, GO:0036155=TAS, GO:0016021=IEA, GO:0019433=IDA, GO:0006644=TAS, GO:0046474=TAS} acylglycerol acyl-chain remodeling, glycerophospholipid biosynthetic process, metabolic process, phospholipid metabolic process, small molecule metabolic process, triglyceride biosynthetic process, triglyceride catabolic process endoplasmic reticulum membrane, integral to membrane, membrane diolein transacylation activity, mono-olein transacylation activity, phospholipase A2 activity, retinyl-palmitate esterase activity, triglyceride lipase activity Human PNPLA6 UniProtKB UniProtKB {GO:0016042=GO_REF:0000037, GO:0008219=GO_REF:0000037, GO:0004622=GO_REF:0000003, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0046470=GO_REF:0000002} Q8IY17 Neuropathy target esterase protein 20130413 {GO:0016042=IEA, GO:0008219=IEA, GO:0004622=IEA, GO:0005789=IEA, GO:0016021=IEA, GO:0046470=IEA} cell death, lipid catabolic process, phosphatidylcholine metabolic process endoplasmic reticulum membrane, integral to membrane lysophospholipase activity Human UniProtKB-SubCell:SL-0097 PNPLA8 Reactome UniProtKB {GO:0006629=GO_REF:0000002, GO:0019369=PMID:15695510, GO:0008219=PMID:15695510, GO:0048471=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0005622=PMID:10744668, GO:0047499=PMID:15695510, GO:0004622=GO_REF:0000003, GO:0006631=PMID:10744668, GO:0005778=PMID:10744668, GO:0050482=PMID:10833412, GO:0005777=PMID:15695510, GO:0005524=PMID:10744668, GO:0043651=PMID:15695510, GO:0016020=PMID:10833412, GO:0000139=GO_REF:0000039, GO:0016787=GO_REF:0000038, GO:0005789=Reactome:REACT_121263, GO:0016021=GO_REF:0000037, GO:0034638=PMID:15695510, GO:0006644=Reactome:REACT_120870, GO:0046338=PMID:15695510, GO:0036151=Reactome:REACT_120829, GO:0036152=Reactome:REACT_121369, GO:0046474=Reactome:REACT_121401} Q9NP80 Calcium-independent phospholipase A2-gamma protein 20130301 {GO:0006629=IEA, GO:0019369=IDA, GO:0008219=IDA, GO:0048471=IEA, GO:0044281=TAS, GO:0005622=IDA, GO:0047499=IDA, GO:0004622=IEA, GO:0006631=IDA, GO:0005778=IDA, GO:0050482=IDA, GO:0005777=IDA, GO:0005524=NAS, GO:0043651=IDA, GO:0016020=IDA, GO:0000139=IEA, GO:0016787=IEA, GO:0005789=TAS, GO:0016021=IEA, GO:0034638=IDA, GO:0006644=TAS, GO:0046338=IDA, GO:0036151=TAS, GO:0036152=TAS, GO:0046474=TAS} arachidonic acid metabolic process, arachidonic acid secretion, cell death, fatty acid metabolic process, glycerophospholipid biosynthetic process, linoleic acid metabolic process, lipid metabolic process, phosphatidylcholine acyl-chain remodeling, phosphatidylcholine catabolic process, phosphatidylethanolamine acyl-chain remodeling, phosphatidylethanolamine catabolic process, phospholipid metabolic process, small molecule metabolic process Golgi membrane, endoplasmic reticulum membrane, integral to membrane, intracellular, membrane, perinuclear region of cytoplasm, peroxisomal membrane, peroxisome ATP binding, calcium-independent phospholipase A2 activity, hydrolase activity, lysophospholipase activity Human PNPO Reactome UniProtKB {GO:0006766=Reactome:REACT_11193, GO:0010181=GO_REF:0000002, GO:0042816=Reactome:REACT_25012, GO:0006767=Reactome:REACT_11238, GO:0044281=Reactome:REACT_111217, GO:0004733=Reactome:REACT_25348, GO:0008615=GO_REF:0000037, GO:0005829=Reactome:REACT_25348} Q9NVS9 Pyridoxine-5'-phosphate oxidase protein 20120112 {GO:0006766=TAS, GO:0010181=IEA, GO:0042816=TAS, GO:0006767=TAS, GO:0044281=TAS, GO:0004733=TAS, GO:0008615=IEA, GO:0005829=TAS} pyridoxine biosynthetic process, small molecule metabolic process, vitamin B6 metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cytosol FMN binding, pyridoxamine-phosphate oxidase activity Human PNPT1 HPA UniProtKB {GO:0005515=PMID:16934922, GO:0097222=PMID:18083837, GO:0000962=PMID:19509288, GO:0005886=GO_REF:0000052, GO:0000965=PMID:18083837, GO:0035458=PMID:16410805, GO:0003723=GO_REF:0000002, GO:0000964=PMID:18083837, GO:0043457=GO_REF:0000024, GO:0035928=PMID:20691904, GO:0035927=PMID:20691904, GO:0005739=GO_REF:0000052, GO:0008266=PMID:18083836, GO:0070207=PMID:20691904, GO:0005758=PMID:16966381, GO:0005737=GO_REF:0000052, GO:0051260=PMID:20691904, GO:2000772=PMID:16055741, GO:0045926=PMID:12721301, GO:0006396=GO_REF:0000002, GO:0043631=PMID:18083836, GO:0000957=PMID:18501193, GO:0000958=PMID:20691904, GO:0006402=PMID:16055741, GO:0006401=PMID:18083836, GO:0071850=PMID:12721301, GO:0071042=PMID:16934922, GO:0035198=PMID:20547861, GO:0034046=PMID:18083836, GO:0004654=PMID:18083836, GO:0070584=GO_REF:0000024, GO:0000175=PMID:19509288, GO:2000627=PMID:20547861, GO:0045025=PMID:19509288, GO:0034599=PMID:18501193, GO:0061014=PMID:16410805} Q8TCS8 Polyribonucleotide nucleotidyltransferase 1, mitochondrial protein 20101115 {GO:0005515=IPI, GO:0097222=IMP, GO:0000962=IDA, GO:0005886=IDA, GO:0000965=IMP, GO:0035458=IDA, GO:0003723=IEA, GO:0000964=IMP, GO:0043457=ISS, GO:0035928=IDA, GO:0035927=IDA, GO:0005739=IDA, GO:0008266=IDA, GO:0070207=IDA, GO:0005758=IDA, GO:0005737=IDA, GO:0051260=IDA, GO:2000772=IDA, GO:0045926=IDA, GO:0006396=IEA, GO:0043631=IDA, GO:0000957=IDA, GO:0000958=IDA, GO:0006402=IDA, GO:0006401=IDA, GO:0071850=IDA, GO:0071042=IDA, GO:0035198=IDA, GO:0034046=IDA, GO:0004654=IDA, GO:0070584=ISS, GO:0000175=IDA, GO:2000627=IDA, GO:0045025=IDA, GO:0034599=IDA, GO:0061014=IMP} RNA catabolic process, RNA import into mitochondrion, RNA polyadenylation, RNA processing, cellular response to interferon-beta, cellular response to oxidative stress, mRNA catabolic process, mitochondrial RNA 3'-end processing, mitochondrial RNA 5'-end processing, mitochondrial RNA catabolic process, mitochondrial mRNA catabolic process, mitochondrial mRNA polyadenylation, mitochondrion morphogenesis, mitotic cell cycle arrest, negative regulation of growth, nuclear polyadenylation-dependent mRNA catabolic process, positive regulation of mRNA catabolic process, positive regulation of miRNA catabolic process, positive regulation of mitochondrial RNA catabolic process, protein homooligomerization, protein homotrimerization, rRNA import into mitochondrion, regulation of cellular respiration, regulation of cellular senescence cytoplasm, mitochondrial degradosome, mitochondrial intermembrane space, mitochondrion, plasma membrane 3'-5'-exoribonuclease activity, RNA binding, miRNA binding, poly(G) RNA binding, poly(U) RNA binding, polyribonucleotide nucleotidyltransferase activity, protein binding Human PNRC1 IntAct UniProtKB {GO:0005515=PMID:17612402, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q12796 Proline-rich nuclear receptor coactivator 1 protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0005634=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus protein binding Human UniProtKB:Q9H1D9 PNRC2 IntAct UniProtKB {GO:0005515=PMID:19150429, GO:0031087=PMID:19150429, GO:0006355=GO_REF:0000037, GO:0000184=PMID:19150429, GO:0000932=PMID:19150429, GO:0005634=PMID:19150429, GO:0006351=GO_REF:0000037} Q9NPJ4 Proline-rich nuclear receptor coactivator 2 protein 20130415 {GO:0005515=IPI, GO:0031087=TAS, GO:0006355=IEA, GO:0000184=IDA, GO:0000932=IDA, GO:0005634=IDA, GO:0006351=IEA} deadenylation-independent decapping of nuclear-transcribed mRNA, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasmic mRNA processing body, nucleus protein binding Human UniProtKB:Q92900 POC1A HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005813=PMID:21399614, GO:0005814=PMID:20008567, GO:0030030=GO_REF:0000037, GO:0005932=PMID:20008567} Q8NBT0 POC1 centriolar protein homolog A protein 20110516 {GO:0005737=IDA, GO:0005813=IDA, GO:0005814=IDA, GO:0030030=IEA, GO:0005932=IDA} cell projection organization centriole, centrosome, cytoplasm, microtubule basal body Human POC1B HPA UniProtKB {GO:0042384=PMID:20008567, GO:0005813=PMID:21399614, GO:0005737=GO_REF:0000052, GO:0005814=PMID:20008567, GO:0005932=PMID:20008567} Q8TC44 POC1 centriolar protein homolog B protein 20111111 {GO:0042384=IMP, GO:0005813=IDA, GO:0005737=IDA, GO:0005814=IDA, GO:0005932=IDA} cilium assembly centriole, centrosome, cytoplasm, microtubule basal body Human POC5 UniProtKB UniProtKB {GO:0005813=PMID:21399614, GO:0007049=GO_REF:0000037, GO:0005814=GO_REF:0000039} Q8NA72 Centrosomal protein POC5 protein 20110517 {GO:0005813=IDA, GO:0007049=IEA, GO:0005814=IEA} cell cycle centriole, centrosome Human PODXL PINC UniProtKB {GO:0022408=GO_REF:0000024, GO:0030335=PMID:18456258, GO:0072015=GO_REF:0000024, GO:0005886=PMID:18456258, GO:0032534=GO_REF:0000024, GO:0031528=GO_REF:0000024, GO:0030175=PMID:18456258, GO:0033634=PMID:18456258, GO:0050900=GO_REF:0000019, GO:0001726=PMID:18456258, GO:0030027=PMID:18456258, GO:0072175=GO_REF:0000024, GO:0016324=GO_REF:0000024, GO:0005737=PMID:18456258, GO:0007162=GO_REF:0000024, GO:0016477=GO_REF:0000024, GO:0005887=PMID:9188463, GO:0036057=GO_REF:0000024, GO:0045121=GO_REF:0000039, GO:0007155=GO_REF:0000037} O00592 Podocalyxin protein 20030904 {GO:0022408=ISS, GO:0030335=IDA, GO:0072015=ISS, GO:0005886=IDA, GO:0032534=ISS, GO:0031528=ISS, GO:0030175=IDA, GO:0033634=IDA, GO:0050900=IEA, GO:0001726=IDA, GO:0030027=IDA, GO:0072175=ISS, GO:0016324=ISS, GO:0005737=IDA, GO:0007162=ISS, GO:0016477=ISS, GO:0005887=TAS, GO:0036057=ISS, GO:0045121=IEA, GO:0007155=IEA} cell adhesion, cell migration, epithelial tube formation, glomerular visceral epithelial cell development, leukocyte migration, negative regulation of cell adhesion, negative regulation of cell-cell adhesion, positive regulation of cell migration, positive regulation of cell-cell adhesion mediated by integrin, regulation of microvillus assembly apical plasma membrane, cytoplasm, filopodium, integral to plasma membrane, lamellipodium, membrane raft, microvillus membrane, plasma membrane, ruffle, slit diaphragm Human PODXL2 PINC UniProtKB {GO:0005515=PMID:18606703, GO:0005887=PMID:10722749, GO:0005539=PMID:10722749, GO:0050901=PMID:18606703} Q9NZ53 Podocalyxin-like protein 2 protein 20030904 {GO:0005515=IPI, GO:0005887=TAS, GO:0005539=TAS, GO:0050901=IDA} leukocyte tethering or rolling integral to plasma membrane glycosaminoglycan binding, protein binding Human POF1B UniProtKB UniProtKB {GO:0003779=GO_REF:0000037} Q8WVV4 Protein POF1B protein 20130413 {GO:0003779=IEA} actin binding Human UniProtKB-KW:KW-0009 POFUT1 Reactome UniProtKB {GO:0006355=PMID:11698403, GO:0016757=GO_REF:0000038, GO:0005783=PMID:15653671, GO:0001756=GO_REF:0000019, GO:0008417=PMID:9023546, GO:0046922=PMID:11698403, GO:0016266=PMID:11698403, GO:0009790=PMID:11698403, GO:0001525=GO_REF:0000019, GO:0007399=GO_REF:0000019, GO:0007507=GO_REF:0000019, GO:0006493=PMID:11524432, GO:0007219=Reactome:REACT_299, GO:0016020=PMID:11524432, GO:0006004=GO_REF:0000037} Q9H488 GDP-fucose protein O-fucosyltransferase 1 protein 20130301 {GO:0006355=NAS, GO:0016757=IEA, GO:0005783=IDA, GO:0001756=IEA, GO:0008417=IDA, GO:0046922=TAS, GO:0016266=TAS, GO:0009790=NAS, GO:0001525=IEA, GO:0007399=IEA, GO:0007507=IEA, GO:0006493=IDA, GO:0007219=TAS, GO:0016020=IDA, GO:0006004=IEA} Notch signaling pathway, O-glycan processing, angiogenesis, embryo development, fucose metabolic process, heart development, nervous system development, protein O-linked glycosylation, regulation of transcription, DNA-dependent, somitogenesis endoplasmic reticulum, membrane fucosyltransferase activity, peptide-O-fucosyltransferase activity, transferase activity, transferring glycosyl groups Human POFUT2 UniProtKB UniProtKB {GO:0010468=GO_REF:0000019, GO:0005794=PMID:15233996, GO:0001707=GO_REF:0000019, GO:0051046=PMID:17395589, GO:0005783=GO_REF:0000039, GO:0046922=PMID:22588082, GO:0010717=GO_REF:0000019, GO:0006004=GO_REF:0000037, GO:0036066=PMID:22588082} Q9Y2G5 GDP-fucose protein O-fucosyltransferase 2 protein 20121026 {GO:0010468=IEA, GO:0005794=IDA, GO:0001707=IEA, GO:0051046=IDA, GO:0005783=IEA, GO:0046922=IDA, GO:0010717=IEA, GO:0006004=IEA, GO:0036066=IDA} fucose metabolic process, mesoderm formation, protein O-linked fucosylation, regulation of epithelial to mesenchymal transition, regulation of gene expression, regulation of secretion Golgi apparatus, endoplasmic reticulum peptide-O-fucosyltransferase activity Human POGK IntAct UniProtKB {GO:0005515=PMID:22939624, GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037} Q9P215 Pogo transposable element with KRAB domain protein 20130415 {GO:0005515=IPI, GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0007275=IEA, GO:0003676=IEA, GO:0003677=IEA} multicellular organismal development, regulation of transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, protein binding Human UniProtKB:P08238 POGLUT1 Reactome UniProtKB {GO:0035251=PMID:21081508, GO:0035252=GO_REF:0000019, GO:0007219=Reactome:REACT_299, GO:0006493=PMID:21949356, GO:0005788=PMID:16524674, GO:0046527=PMID:21949356, GO:0072358=GO_REF:0000019, GO:0008593=GO_REF:0000019} Q8NBL1 Protein O-glucosyltransferase 1 protein 20130301 {GO:0035251=IDA, GO:0035252=IEA, GO:0007219=TAS, GO:0006493=IDA, GO:0005788=IDA, GO:0046527=IDA, GO:0072358=IEA, GO:0008593=IEA} Notch signaling pathway, cardiovascular system development, protein O-linked glycosylation, regulation of Notch signaling pathway endoplasmic reticulum lumen UDP-glucosyltransferase activity, UDP-xylosyltransferase activity, glucosyltransferase activity Human POGZ HPA UniProtKB {GO:0005515=PMID:10976766, GO:0000790=PMID:20562864, GO:0005737=GO_REF:0000052, GO:0051382=PMID:20562864, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0007064=PMID:20562864, GO:0051301=GO_REF:0000037} Q7Z3K3 Pogo transposable element with ZNF domain protein 20101115 {GO:0005515=IPI, GO:0000790=IDA, GO:0005737=IDA, GO:0051382=IMP, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003677=IEA, GO:0007064=IMP, GO:0051301=IEA} cell division, kinetochore assembly, mitotic sister chromatid cohesion cytoplasm, nuclear chromatin, nucleolus, nucleus DNA binding, protein binding, zinc ion binding Human POLA1 GOC UniProtKB {GO:0005515=PMID:16438930, GO:0008408=GO_REF:0000033, GO:0005658=PMID:2175912, GO:0008283=PMID:3359994, GO:0003887=PMID:4084590, GO:0005634=GO_REF:0000052, GO:0005635=PMID:9518481, GO:0006303=PMID:11470886, GO:0019985=GO_REF:0000033, GO:0046872=GO_REF:0000037, GO:0016363=PMID:1903085, GO:0043231=GO_REF:0000052, GO:0000084=Reactome:REACT_899, GO:0006273=PMID:2175912, GO:0000082=Reactome:REACT_1783, GO:0005737=GO_REF:0000052, GO:0006271=Reactome:REACT_932, GO:0000083=Reactome:REACT_683, GO:0006272=PMID:2175912, GO:0000723=Reactome:REACT_7970, GO:0000166=PMID:3139084, GO:0006270=Reactome:REACT_2244, GO:0001882=GO_REF:0000002, GO:0000722=Reactome:REACT_7993, GO:0006297=GO_REF:0000033, GO:0000785=PMID:9815285, GO:0051539=GO_REF:0000037, GO:0046982=GO_REF:0000019, GO:0003896=PMID:2175912, GO:0005730=GO_REF:0000052, GO:0003677=PMID:16762037, GO:0006260=PMID:16762037, GO:0006281=PMID:3335506, GO:0003682=PMID:16762037, GO:0019048=GO_REF:0000037, GO:0000731=PMID:1508673, GO:0006269=PMID:2175912, GO:0005654=Reactome:REACT_22145, GO:0000278=Reactome:REACT_152, GO:0032201=Reactome:REACT_7961} P09884 DNA polymerase alpha catalytic subunit protein 20130413 {GO:0005515=IPI, GO:0008408=IBA, GO:0005658=IDA, GO:0008283=IDA, GO:0003887=IMP, GO:0005634=IDA, GO:0005635=IDA, GO:0006303=IMP, GO:0019985=IBA, GO:0046872=IEA, GO:0016363=IDA, GO:0043231=IDA, GO:0000084=TAS, GO:0006273=IDA, GO:0000082=TAS, GO:0005737=IDA, GO:0006271=TAS, GO:0000083=TAS, GO:0006272=IDA, GO:0000723=TAS, GO:0000166=IDA, GO:0006270=TAS, GO:0001882=IEA, GO:0000722=TAS, GO:0006297=IBA, GO:0000785=IDA, GO:0051539=IEA, GO:0046982=IEA, GO:0003896=IDA, GO:0005730=IDA, GO:0003677=IDA, GO:0006260=IMP, GO:0006281=IDA, GO:0003682=IDA, GO:0019048=IEA, GO:0000731=IMP, GO:0006269=IDA, GO:0005654=TAS, GO:0000278=TAS, GO:0032201=TAS} DNA repair, DNA replication, DNA replication initiation, DNA replication, synthesis of RNA primer, DNA strand elongation involved in DNA replication, DNA synthesis involved in DNA repair, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, cell proliferation, double-strand break repair via nonhomologous end joining, lagging strand elongation, leading strand elongation, mitotic cell cycle, nucleotide-excision repair, DNA gap filling, regulation of transcription involved in G1/S phase of mitotic cell cycle, telomere maintenance, telomere maintenance via recombination, telomere maintenance via semi-conservative replication, translesion synthesis, virus-host interaction alpha DNA polymerase:primase complex, chromatin, cytoplasm, intracellular membrane-bounded organelle, nuclear envelope, nuclear matrix, nucleolus, nucleoplasm, nucleus 3'-5' exonuclease activity, 4 iron, 4 sulfur cluster binding, DNA binding, DNA primase activity, DNA-directed DNA polymerase activity, chromatin binding, metal ion binding, nucleoside binding, nucleotide binding, protein binding, protein heterodimerization activity Human POLA2 HPA UniProtKB {GO:0046982=GO_REF:0000019, GO:0005658=GO_REF:0000019, GO:0003887=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000002, GO:0006260=PMID:8223465, GO:0000084=Reactome:REACT_899, GO:0003674=GO_REF:0000015, GO:0006271=Reactome:REACT_932, GO:0005737=GO_REF:0000052, GO:0000082=Reactome:REACT_1783, GO:0000723=Reactome:REACT_7970, GO:0006270=Reactome:REACT_2244, GO:0000722=Reactome:REACT_7993, GO:0005654=Reactome:REACT_8008, GO:0000278=Reactome:REACT_152, GO:0032201=Reactome:REACT_7961, GO:0000060=GO_REF:0000019} Q14181 DNA polymerase alpha subunit B protein 20110516 {GO:0046982=IEA, GO:0005658=IEA, GO:0003887=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0006260=NAS, GO:0000084=TAS, GO:0003674=ND, GO:0006271=TAS, GO:0005737=IDA, GO:0000082=TAS, GO:0000723=TAS, GO:0006270=TAS, GO:0000722=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0032201=TAS, GO:0000060=IEA} DNA replication, DNA replication initiation, DNA strand elongation involved in DNA replication, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, mitotic cell cycle, protein import into nucleus, translocation, telomere maintenance, telomere maintenance via recombination, telomere maintenance via semi-conservative replication alpha DNA polymerase:primase complex, cytoplasm, nucleolus, nucleoplasm, nucleus DNA binding, DNA-directed DNA polymerase activity, molecular_function, protein heterodimerization activity Human POLB Reactome UniProtKB {GO:0008017=PMID:15725623, GO:0005515=PMID:9207062, GO:0008219=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0003887=PMID:9207062, GO:0045471=GO_REF:0000019, GO:0005874=PMID:15725623, GO:0016779=GO_REF:0000002, GO:0005634=PMID:21362556, GO:0003677=GO_REF:0000002, GO:0006974=PMID:21362556, GO:0046872=GO_REF:0000019, GO:0016829=PMID:16600869, GO:0003684=GO_REF:0000019, GO:0006261=PMID:8168825, GO:0005737=PMID:15725623, GO:0006290=GO_REF:0000019, GO:0006281=Reactome:REACT_216, GO:0006284=Reactome:REACT_1104, GO:0005654=Reactome:REACT_2224, GO:0005876=PMID:15725623, GO:0006297=PMID:20227374, GO:0019899=PMID:21362556} P06746 DNA polymerase beta protein 20130213 {GO:0008017=IDA, GO:0005515=IPI, GO:0008219=IEA, GO:0043066=IEA, GO:0003887=IDA, GO:0045471=IEA, GO:0005874=IDA, GO:0016779=IEA, GO:0005634=IDA, GO:0003677=IEA, GO:0006974=IMP, GO:0046872=IEA, GO:0016829=IDA, GO:0003684=IEA, GO:0006261=TAS, GO:0005737=IDA, GO:0006290=IEA, GO:0006281=TAS, GO:0006284=TAS, GO:0005654=TAS, GO:0005876=IDA, GO:0006297=IMP, GO:0019899=IPI} DNA repair, DNA-dependent DNA replication, base-excision repair, cell death, negative regulation of apoptotic process, nucleotide-excision repair, DNA gap filling, pyrimidine dimer repair, response to DNA damage stimulus, response to ethanol cytoplasm, microtubule, nucleoplasm, nucleus, spindle microtubule DNA binding, DNA-directed DNA polymerase activity, damaged DNA binding, enzyme binding, lyase activity, metal ion binding, microtubule binding, nucleotidyltransferase activity, protein binding Human POLD1 IntAct UniProtKB {GO:0043625=GO_REF:0000033, GO:0005515=PMID:16510448, GO:0008408=GO_REF:0000033, GO:0003887=PMID:16762037, GO:0005634=PMID:16762037, GO:0044281=Reactome:REACT_111217, GO:0019985=GO_REF:0000033, GO:0046872=GO_REF:0000037, GO:0000084=Reactome:REACT_899, GO:0006271=Reactome:REACT_932, GO:0000109=PMID:20713449, GO:0000166=GO_REF:0000002, GO:0000723=Reactome:REACT_7970, GO:0000722=Reactome:REACT_8027, GO:0006297=Reactome:REACT_1998, GO:0009411=PMID:3146346, GO:0051539=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0003677=PMID:16762037, GO:0006260=PMID:16762037, GO:0007346=GO_REF:0000033, GO:0006281=Reactome:REACT_216, GO:0045004=GO_REF:0000033, GO:0006283=Reactome:REACT_1628, GO:0006284=Reactome:REACT_1104, GO:0003682=PMID:16762037, GO:0000731=PMID:3335506, GO:0006287=PMID:10559261, GO:0005654=Reactome:REACT_8029, GO:0006289=Reactome:REACT_1826, GO:0043137=GO_REF:0000033, GO:0000278=Reactome:REACT_152, GO:0032201=Reactome:REACT_7961} P28340 DNA polymerase delta catalytic subunit protein 20130415 {GO:0043625=IBA, GO:0005515=IPI, GO:0008408=IBA, GO:0003887=IMP, GO:0005634=IDA, GO:0044281=TAS, GO:0019985=IBA, GO:0046872=IEA, GO:0000084=TAS, GO:0006271=TAS, GO:0000109=IDA, GO:0000166=IEA, GO:0000723=TAS, GO:0000722=TAS, GO:0006297=TAS, GO:0009411=TAS, GO:0051539=IEA, GO:0003676=IEA, GO:0003677=IDA, GO:0006260=IMP, GO:0007346=IBA, GO:0006281=TAS, GO:0045004=IBA, GO:0006283=TAS, GO:0006284=TAS, GO:0003682=IDA, GO:0000731=IDA, GO:0006287=IDA, GO:0005654=TAS, GO:0006289=TAS, GO:0043137=IBA, GO:0000278=TAS, GO:0032201=TAS} DNA repair, DNA replication, DNA replication proofreading, DNA replication, removal of RNA primer, DNA strand elongation involved in DNA replication, DNA synthesis involved in DNA repair, S phase of mitotic cell cycle, base-excision repair, base-excision repair, gap-filling, mitotic cell cycle, nucleotide-excision repair, nucleotide-excision repair, DNA gap filling, regulation of mitotic cell cycle, response to UV, small molecule metabolic process, telomere maintenance, telomere maintenance via recombination, telomere maintenance via semi-conservative replication, transcription-coupled nucleotide-excision repair, translesion synthesis delta DNA polymerase complex, nucleoplasm, nucleotide-excision repair complex, nucleus 3'-5' exonuclease activity, 4 iron, 4 sulfur cluster binding, DNA binding, DNA-directed DNA polymerase activity, chromatin binding, metal ion binding, nucleic acid binding, nucleotide binding, protein binding Human UniProtKB:P12004 POLD2 HPA UniProtKB {GO:0005515=PMID:16510448, GO:0003887=GO_REF:0000003, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000002, GO:0006260=PMID:8530069, GO:0000084=Reactome:REACT_899, GO:0006261=GO_REF:0000019, GO:0006271=Reactome:REACT_932, GO:0006281=Reactome:REACT_216, GO:0000723=Reactome:REACT_7970, GO:0006283=Reactome:REACT_1628, GO:0006284=Reactome:REACT_1104, GO:0000722=Reactome:REACT_8027, GO:0006297=Reactome:REACT_1998, GO:0005654=Reactome:REACT_8029, GO:0006289=Reactome:REACT_1826, GO:0000278=Reactome:REACT_152, GO:0032201=Reactome:REACT_7961} P49005 DNA polymerase delta subunit 2 protein 20111111 {GO:0005515=IPI, GO:0003887=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0006260=TAS, GO:0000084=TAS, GO:0006261=IEA, GO:0006271=TAS, GO:0006281=TAS, GO:0000723=TAS, GO:0006283=TAS, GO:0006284=TAS, GO:0000722=TAS, GO:0006297=TAS, GO:0005654=TAS, GO:0006289=TAS, GO:0000278=TAS, GO:0032201=TAS} DNA repair, DNA replication, DNA strand elongation involved in DNA replication, DNA-dependent DNA replication, S phase of mitotic cell cycle, base-excision repair, mitotic cell cycle, nucleotide-excision repair, nucleotide-excision repair, DNA gap filling, telomere maintenance, telomere maintenance via recombination, telomere maintenance via semi-conservative replication, transcription-coupled nucleotide-excision repair nucleolus, nucleoplasm, nucleus DNA binding, DNA-directed DNA polymerase activity, protein binding NOT Human POLD3 HPA UniProtKB {GO:0005515=PMID:16510448, GO:0043625=PMID:10219083, GO:0003887=PMID:10219083, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006260=GO_REF:0000002, GO:0005739=GO_REF:0000052, GO:0000084=Reactome:REACT_899, GO:0006261=GO_REF:0000019, GO:0006271=Reactome:REACT_932, GO:0006281=Reactome:REACT_216, GO:0000723=Reactome:REACT_7970, GO:0006283=Reactome:REACT_1628, GO:0006284=Reactome:REACT_1104, GO:0000731=PMID:7910606, GO:0000722=Reactome:REACT_8027, GO:0005654=Reactome:REACT_8029, GO:0006297=Reactome:REACT_1998, GO:0006289=Reactome:REACT_1826, GO:0006298=PMID:9099749, GO:0000278=Reactome:REACT_152, GO:0032201=Reactome:REACT_7961} Q32N00 POLD3 protein protein 20110516 {GO:0005515=IPI, GO:0043625=NAS, GO:0003887=NAS, GO:0005730=IDA, GO:0005634=IDA, GO:0006260=IEA, GO:0005739=IDA, GO:0000084=TAS, GO:0006261=IEA, GO:0006271=TAS, GO:0006281=TAS, GO:0000723=TAS, GO:0006283=TAS, GO:0006284=TAS, GO:0000731=NAS, GO:0000722=TAS, GO:0005654=TAS, GO:0006297=TAS, GO:0006289=TAS, GO:0006298=NAS, GO:0000278=TAS, GO:0032201=TAS} DNA repair, DNA replication, DNA strand elongation involved in DNA replication, DNA synthesis involved in DNA repair, DNA-dependent DNA replication, S phase of mitotic cell cycle, base-excision repair, mismatch repair, mitotic cell cycle, nucleotide-excision repair, nucleotide-excision repair, DNA gap filling, telomere maintenance, telomere maintenance via recombination, telomere maintenance via semi-conservative replication, transcription-coupled nucleotide-excision repair delta DNA polymerase complex, mitochondrion, nucleolus, nucleoplasm, nucleus DNA-directed DNA polymerase activity, protein binding Human POLD4 IntAct UniProtKB {GO:0005515=PMID:16510448, GO:0003887=GO_REF:0000037, GO:0005634=PMID:10751307, GO:0006260=PMID:10751307, GO:0000084=Reactome:REACT_899, GO:0006271=Reactome:REACT_932, GO:0006281=Reactome:REACT_216, GO:0001938=GO_REF:0000019, GO:0000723=Reactome:REACT_7970, GO:0006283=Reactome:REACT_1628, GO:0006284=Reactome:REACT_1104, GO:0000722=Reactome:REACT_8027, GO:0006297=Reactome:REACT_1998, GO:0005654=Reactome:REACT_8029, GO:0006289=Reactome:REACT_1826, GO:0000278=Reactome:REACT_152, GO:0032201=Reactome:REACT_7961} Q9HCU8 DNA polymerase delta subunit 4 protein 20130415 {GO:0005515=IPI, GO:0003887=IEA, GO:0005634=TAS, GO:0006260=TAS, GO:0000084=TAS, GO:0006271=TAS, GO:0006281=TAS, GO:0001938=IEA, GO:0000723=TAS, GO:0006283=TAS, GO:0006284=TAS, GO:0000722=TAS, GO:0006297=TAS, GO:0005654=TAS, GO:0006289=TAS, GO:0000278=TAS, GO:0032201=TAS} DNA repair, DNA replication, DNA strand elongation involved in DNA replication, S phase of mitotic cell cycle, base-excision repair, mitotic cell cycle, nucleotide-excision repair, nucleotide-excision repair, DNA gap filling, positive regulation of endothelial cell proliferation, telomere maintenance, telomere maintenance via recombination, telomere maintenance via semi-conservative replication, transcription-coupled nucleotide-excision repair nucleoplasm, nucleus DNA-directed DNA polymerase activity, protein binding Human UniProtKB:P49005 POLDIP2 BHF-UCL UniProtKB {GO:0042645=PMID:18063578, GO:0005739=GO_REF:0000054, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000002} Q9Y2S7 Polymerase delta-interacting protein 2 protein 20090218 {GO:0042645=IDA, GO:0005739=IDA, GO:0005634=IEA, GO:0003677=IEA} mitochondrial nucleoid, mitochondrion, nucleus DNA binding Human POLDIP3 HPA UniProtKB {GO:0005515=PMID:18423201, GO:0005737=PMID:18423201, GO:0016607=PMID:18423201, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0045727=PMID:18423201, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0035145=PMID:18423201, GO:0043231=GO_REF:0000052} Q9BY77 Polymerase delta-interacting protein 3 protein 20100326 {GO:0005515=IPI, GO:0005737=TAS, GO:0016607=IDA, GO:0000166=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0045727=IMP, GO:0005634=IDA, GO:0003676=IEA, GO:0035145=IDA, GO:0043231=IDA} positive regulation of translation cytoplasm, exon-exon junction complex, intracellular membrane-bounded organelle, nuclear speck, nucleolus, nucleus RNA binding, nucleic acid binding, nucleotide binding, protein binding Human POLE Reactome UniProtKB {GO:0008622=PMID:10801849, GO:0051539=GO_REF:0000037, GO:0003887=PMID:16762037, GO:0005634=PMID:16762037, GO:0003676=GO_REF:0000002, GO:0003677=PMID:16762037, GO:0000084=Reactome:REACT_899, GO:0006260=PMID:16762037, GO:0000082=Reactome:REACT_1783, GO:0006281=Reactome:REACT_216, GO:0000723=Reactome:REACT_7970, GO:0000166=GO_REF:0000002, GO:0006283=Reactome:REACT_1628, GO:0006270=Reactome:REACT_2244, GO:0003682=PMID:16762037, GO:0000722=Reactome:REACT_7993, GO:0000731=PMID:1730053, GO:0006287=PMID:10559260, GO:0005654=Reactome:REACT_7998, GO:0008270=GO_REF:0000002, GO:0006297=Reactome:REACT_1998, GO:0006289=Reactome:REACT_1826, GO:0000278=Reactome:REACT_152, GO:0032201=Reactome:REACT_7961} Q07864 DNA polymerase epsilon catalytic subunit A protein 20130213 {GO:0008622=IDA, GO:0051539=IEA, GO:0003887=IMP, GO:0005634=IDA, GO:0003676=IEA, GO:0003677=IDA, GO:0000084=TAS, GO:0006260=IMP, GO:0000082=TAS, GO:0006281=TAS, GO:0000723=TAS, GO:0000166=IEA, GO:0006283=TAS, GO:0006270=TAS, GO:0003682=IDA, GO:0000722=TAS, GO:0000731=IMP, GO:0006287=IDA, GO:0005654=TAS, GO:0008270=IEA, GO:0006297=TAS, GO:0006289=TAS, GO:0000278=TAS, GO:0032201=TAS} DNA repair, DNA replication, DNA replication initiation, DNA synthesis involved in DNA repair, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, base-excision repair, gap-filling, mitotic cell cycle, nucleotide-excision repair, nucleotide-excision repair, DNA gap filling, telomere maintenance, telomere maintenance via recombination, telomere maintenance via semi-conservative replication, transcription-coupled nucleotide-excision repair epsilon DNA polymerase complex, nucleoplasm, nucleus 4 iron, 4 sulfur cluster binding, DNA binding, DNA-directed DNA polymerase activity, chromatin binding, nucleic acid binding, nucleotide binding, zinc ion binding Human POLE2 HPA UniProtKB {GO:0008622=PMID:10801849, GO:0003887=GO_REF:0000003, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0006260=PMID:9405441, GO:0000084=Reactome:REACT_899, GO:0000082=Reactome:REACT_1783, GO:0006281=Reactome:REACT_216, GO:0000723=Reactome:REACT_7970, GO:0006270=Reactome:REACT_2244, GO:0006283=Reactome:REACT_1628, GO:0000722=Reactome:REACT_7993, GO:0006297=Reactome:REACT_1998, GO:0005654=Reactome:REACT_7998, GO:0006289=Reactome:REACT_1826, GO:0000278=Reactome:REACT_152, GO:0032201=Reactome:REACT_7961} P56282 DNA polymerase epsilon subunit 2 protein 20100326 {GO:0008622=IDA, GO:0003887=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0043231=IDA, GO:0006260=TAS, GO:0000084=TAS, GO:0000082=TAS, GO:0006281=TAS, GO:0000723=TAS, GO:0006270=TAS, GO:0006283=TAS, GO:0000722=TAS, GO:0006297=TAS, GO:0005654=TAS, GO:0006289=TAS, GO:0000278=TAS, GO:0032201=TAS} DNA repair, DNA replication, DNA replication initiation, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, mitotic cell cycle, nucleotide-excision repair, nucleotide-excision repair, DNA gap filling, telomere maintenance, telomere maintenance via recombination, telomere maintenance via semi-conservative replication, transcription-coupled nucleotide-excision repair epsilon DNA polymerase complex, intracellular membrane-bounded organelle, nucleolus, nucleoplasm, nucleus DNA binding, DNA-directed DNA polymerase activity Human POLE3 BHF-UCL UniProtKB {GO:0005515=PMID:22190034, GO:0006260=PMID:10801849, GO:0043565=GO_REF:0000002, GO:0008622=PMID:10801849, GO:0043966=PMID:18838386, GO:0046982=GO_REF:0000002, GO:0003887=GO_REF:0000003, GO:0005671=PMID:18838386, GO:0005634=PMID:10801849} Q9NRF9 DNA polymerase epsilon subunit 3 protein 20101105 {GO:0005515=IPI, GO:0006260=TAS, GO:0043565=IEA, GO:0008622=IDA, GO:0043966=IDA, GO:0046982=IEA, GO:0003887=IEA, GO:0005671=IDA, GO:0005634=TAS} DNA replication, histone H3 acetylation Ada2/Gcn5/Ada3 transcription activator complex, epsilon DNA polymerase complex, nucleus DNA-directed DNA polymerase activity, protein binding, protein heterodimerization activity, sequence-specific DNA binding Human POLE4 BHF-UCL UniProtKB {GO:0005515=PMID:22190034, GO:0043565=GO_REF:0000002, GO:0008622=PMID:10801849, GO:0043966=PMID:18838386, GO:0046982=GO_REF:0000002, GO:0003887=GO_REF:0000003, GO:0005671=PMID:18838386, GO:0005634=PMID:10801849} Q9NR33 DNA polymerase epsilon subunit 4 protein 20101105 {GO:0005515=IPI, GO:0043565=IEA, GO:0008622=IDA, GO:0043966=IDA, GO:0046982=IEA, GO:0003887=IEA, GO:0005671=IDA, GO:0005634=TAS} histone H3 acetylation Ada2/Gcn5/Ada3 transcription activator complex, epsilon DNA polymerase complex, nucleus DNA-directed DNA polymerase activity, protein binding, protein heterodimerization activity, sequence-specific DNA binding Human POLG BHF-UCL UniProtKB {GO:0042645=PMID:18063578, GO:0005515=PMID:16488880, GO:0008219=GO_REF:0000037, GO:0003887=PMID:15177179, GO:0007568=GO_REF:0000019, GO:0005743=GO_REF:0000019, GO:0005760=GO_REF:0000019, GO:0006259=PMID:8884268, GO:0002020=PMID:14739292, GO:0003677=GO_REF:0000037, GO:0006260=GO_REF:0000002, GO:0005739=PMID:8884268, GO:0006261=PMID:3619920, GO:0004527=GO_REF:0000019, GO:0003682=PMID:18063578, GO:0006287=PMID:15177179, GO:0006264=GO_REF:0000019} P54098 DNA polymerase subunit gamma-1 protein 20090218 {GO:0042645=IDA, GO:0005515=IPI, GO:0008219=IEA, GO:0003887=IDA, GO:0007568=IEA, GO:0005743=IEA, GO:0005760=IEA, GO:0006259=TAS, GO:0002020=IPI, GO:0003677=IEA, GO:0006260=IEA, GO:0005739=TAS, GO:0006261=TAS, GO:0004527=IEA, GO:0003682=IDA, GO:0006287=IDA, GO:0006264=IEA} DNA metabolic process, DNA replication, DNA-dependent DNA replication, aging, base-excision repair, gap-filling, cell death, mitochondrial DNA replication gamma DNA polymerase complex, mitochondrial inner membrane, mitochondrial nucleoid, mitochondrion DNA binding, DNA-directed DNA polymerase activity, chromatin binding, exonuclease activity, protease binding, protein binding Human POLG2 BHF-UCL UniProtKB {GO:0042645=PMID:18063578, GO:0005739=GO_REF:0000029, GO:0006260=PMID:10608893, GO:0006261=PMID:9153213, GO:0006281=PMID:10608893, GO:0003697=GO_REF:0000029, GO:0003887=GO_REF:0000029, GO:0000262=PMID:9153213, GO:0042802=GO_REF:0000019} Q9UHN1 DNA polymerase subunit gamma-2, mitochondrial protein 20090218 {GO:0042645=IDA, GO:0005739=NAS, GO:0006260=NAS, GO:0006261=TAS, GO:0006281=NAS, GO:0003697=NAS, GO:0003887=NAS, GO:0000262=TAS, GO:0042802=IEA} DNA repair, DNA replication, DNA-dependent DNA replication mitochondrial chromosome, mitochondrial nucleoid, mitochondrion DNA-directed DNA polymerase activity, identical protein binding, single-stranded DNA binding Human POLH HPA UniProtKB {GO:0003887=Reactome:REACT_2016, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006301=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0003684=GO_REF:0000002, GO:0006260=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0010225=PMID:17563354, GO:0006281=Reactome:REACT_216, GO:0006290=GO_REF:0000019, GO:0006282=PMID:10398605, GO:0000731=PMID:17563354, GO:0005654=Reactome:REACT_2016} Q9Y253 DNA polymerase eta protein 20080818 {GO:0003887=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0006301=IEA, GO:0046872=IEA, GO:0003684=IEA, GO:0006260=IEA, GO:0005737=IDA, GO:0010225=IDA, GO:0006281=TAS, GO:0006290=IEA, GO:0006282=TAS, GO:0000731=IDA, GO:0005654=TAS} DNA repair, DNA replication, DNA synthesis involved in DNA repair, postreplication repair, pyrimidine dimer repair, regulation of DNA repair, response to UV-C cytoplasm, nucleolus, nucleoplasm, nucleus DNA-directed DNA polymerase activity, damaged DNA binding, metal ion binding Human POLI HPA UniProtKB {GO:0005515=PMID:19060904, GO:0005622=GO_REF:0000054, GO:0006260=GO_REF:0000037, GO:0003684=GO_REF:0000002, GO:0006281=GO_REF:0000037, GO:0003887=GO_REF:0000003, GO:0005634=GO_REF:0000052, GO:0005654=PMID:10458907, GO:0046872=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q9UNA4 DNA polymerase iota protein 20081203 {GO:0005515=IPI, GO:0005622=IDA, GO:0006260=IEA, GO:0003684=IEA, GO:0006281=IEA, GO:0003887=IEA, GO:0005634=IDA, GO:0005654=TAS, GO:0046872=IEA, GO:0043231=IDA} DNA repair, DNA replication intracellular, intracellular membrane-bounded organelle, nucleoplasm, nucleus DNA-directed DNA polymerase activity, damaged DNA binding, metal ion binding, protein binding Human POLK UniProtKB UniProtKB {GO:0006260=GO_REF:0000037, GO:0003684=GO_REF:0000002, GO:0006281=PMID:10620008, GO:0003887=GO_REF:0000003, GO:0006297=PMID:20227374, GO:0005634=GO_REF:0000039, GO:0046872=GO_REF:0000037} Q9UBT6 DNA polymerase kappa protein 20110318 {GO:0006260=IEA, GO:0003684=IEA, GO:0006281=TAS, GO:0003887=IEA, GO:0006297=IMP, GO:0005634=IEA, GO:0046872=IEA} DNA repair, DNA replication, nucleotide-excision repair, DNA gap filling nucleus DNA-directed DNA polymerase activity, damaged DNA binding, metal ion binding Human POLL UniProtKB UniProtKB {GO:0006260=PMID:10982892, GO:0006281=GO_REF:0000002, GO:0003887=PMID:10982892, GO:0016779=GO_REF:0000002, GO:0005634=PMID:10982892, GO:0016446=PMID:10982892, GO:0006289=PMID:10982892, GO:0003824=GO_REF:0000002, GO:0003677=PMID:10982892, GO:0046872=GO_REF:0000037, GO:0016829=GO_REF:0000037} Q9UGP5 DNA polymerase lambda protein 20030110 {GO:0006260=NAS, GO:0006281=IEA, GO:0003887=NAS, GO:0016779=IEA, GO:0005634=NAS, GO:0016446=NAS, GO:0006289=IDA, GO:0003824=IEA, GO:0003677=NAS, GO:0046872=IEA, GO:0016829=IEA} DNA repair, DNA replication, nucleotide-excision repair, somatic hypermutation of immunoglobulin genes nucleus DNA binding, DNA-directed DNA polymerase activity, catalytic activity, lyase activity, metal ion binding, nucleotidyltransferase activity Human POLM UniProtKB UniProtKB {GO:0006281=GO_REF:0000037, GO:0003887=GO_REF:0000003, GO:0030183=GO_REF:0000019, GO:0016779=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0006310=GO_REF:0000037, GO:0016446=GO_REF:0000019, GO:0003677=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q9NP87 DNA-directed DNA/RNA polymerase mu protein 20130413 {GO:0006281=IEA, GO:0003887=IEA, GO:0030183=IEA, GO:0016779=IEA, GO:0005634=IEA, GO:0006310=IEA, GO:0016446=IEA, GO:0003677=IEA, GO:0046872=IEA} B cell differentiation, DNA recombination, DNA repair, somatic hypermutation of immunoglobulin genes nucleus DNA binding, DNA-directed DNA polymerase activity, metal ion binding, nucleotidyltransferase activity Human UniProtKB-SubCell:SL-0191 POLN UniProtKB UniProtKB {GO:0006260=GO_REF:0000037, GO:0006281=GO_REF:0000037, GO:0003887=GO_REF:0000003, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037} Q7Z5Q5 DNA polymerase nu protein 20130413 {GO:0006260=IEA, GO:0006281=IEA, GO:0003887=IEA, GO:0005634=IEA, GO:0003677=IEA} DNA repair, DNA replication nucleus DNA binding, DNA-directed DNA polymerase activity Human UniProtKB-SubCell:SL-0191 POLQ PINC UniProtKB {GO:0003684=PMID:10395804, GO:0043142=PMID:14576298, GO:0008026=GO_REF:0000002, GO:0006260=GO_REF:0000002, GO:0006281=GO_REF:0000019, GO:0003887=PMID:14576298, GO:0005654=PMID:10395804, GO:0005524=GO_REF:0000037} O75417 DNA polymerase theta protein 20030904 {GO:0003684=TAS, GO:0043142=IDA, GO:0008026=IEA, GO:0006260=IEA, GO:0006281=IEA, GO:0003887=IDA, GO:0005654=TAS, GO:0005524=IEA} DNA repair, DNA replication nucleoplasm ATP binding, ATP-dependent helicase activity, DNA-directed DNA polymerase activity, damaged DNA binding, single-stranded DNA-dependent ATPase activity Human POLR1A Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0005736=GO_REF:0000029, GO:0003899=GO_REF:0000003, GO:0006363=Reactome:REACT_1074, GO:0006362=Reactome:REACT_2204, GO:0006361=Reactome:REACT_1974, GO:0006360=Reactome:REACT_1309, GO:0005654=Reactome:REACT_2228, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000002, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000002} O95602 DNA-directed RNA polymerase I subunit RPA1 protein 20130213 {GO:0010467=TAS, GO:0005736=NAS, GO:0003899=IEA, GO:0006363=TAS, GO:0006362=TAS, GO:0006361=TAS, GO:0006360=TAS, GO:0005654=TAS, GO:0008270=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} gene expression, termination of RNA polymerase I transcription, transcription elongation from RNA polymerase I promoter, transcription from RNA polymerase I promoter, transcription initiation from RNA polymerase I promoter, transcription, DNA-dependent DNA-directed RNA polymerase I complex, nucleoplasm, nucleus DNA binding, DNA-directed RNA polymerase activity, zinc ion binding Human POLR1B HPA UniProtKB {GO:0005515=PMID:20208542, GO:0010467=Reactome:REACT_71, GO:0017126=GO_REF:0000019, GO:0003899=GO_REF:0000003, GO:0007566=GO_REF:0000019, GO:0009303=GO_REF:0000019, GO:0006363=Reactome:REACT_1074, GO:0006362=Reactome:REACT_2204, GO:0005730=GO_REF:0000052, GO:0006361=Reactome:REACT_1974, GO:0032549=GO_REF:0000002, GO:0006360=Reactome:REACT_1309, GO:0005634=GO_REF:0000002, GO:0009790=GO_REF:0000019, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0005736=GO_REF:0000019, GO:0005654=Reactome:REACT_2228} Q9H9Y6 DNA-directed RNA polymerase I subunit RPA2 protein 20110516 {GO:0005515=IPI, GO:0010467=TAS, GO:0017126=IEA, GO:0003899=IEA, GO:0007566=IEA, GO:0009303=IEA, GO:0006363=TAS, GO:0006362=TAS, GO:0005730=IDA, GO:0006361=TAS, GO:0032549=IEA, GO:0006360=TAS, GO:0005634=IEA, GO:0009790=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0046872=IEA, GO:0005737=IDA, GO:0005736=IEA, GO:0005654=TAS} embryo development, embryo implantation, gene expression, nucleologenesis, rRNA transcription, termination of RNA polymerase I transcription, transcription elongation from RNA polymerase I promoter, transcription from RNA polymerase I promoter, transcription initiation from RNA polymerase I promoter, transcription, DNA-dependent DNA-directed RNA polymerase I complex, cytoplasm, nucleolus, nucleoplasm, nucleus DNA binding, DNA-directed RNA polymerase activity, metal ion binding, protein binding, ribonucleoside binding Human POLR1C Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0006386=Reactome:REACT_63, GO:0006385=Reactome:REACT_756, GO:0003899=GO_REF:0000037, GO:0006363=Reactome:REACT_1074, GO:0006362=Reactome:REACT_2204, GO:0006361=Reactome:REACT_1974, GO:0006360=Reactome:REACT_1309, GO:0003677=GO_REF:0000002, GO:0006383=Reactome:REACT_1371, GO:0006351=GO_REF:0000002, GO:0005736=PMID:9540830, GO:0046983=GO_REF:0000002, GO:0005654=Reactome:REACT_2228} O15160 DNA-directed RNA polymerases I and III subunit RPAC1 protein 20130213 {GO:0010467=TAS, GO:0006386=TAS, GO:0006385=TAS, GO:0003899=IEA, GO:0006363=TAS, GO:0006362=TAS, GO:0006361=TAS, GO:0006360=TAS, GO:0003677=IEA, GO:0006383=TAS, GO:0006351=IEA, GO:0005736=TAS, GO:0046983=IEA, GO:0005654=TAS} gene expression, termination of RNA polymerase I transcription, termination of RNA polymerase III transcription, transcription elongation from RNA polymerase I promoter, transcription elongation from RNA polymerase III promoter, transcription from RNA polymerase I promoter, transcription from RNA polymerase III promoter, transcription initiation from RNA polymerase I promoter, transcription, DNA-dependent DNA-directed RNA polymerase I complex, nucleoplasm DNA binding, DNA-directed RNA polymerase activity, protein dimerization activity Human POLR1D Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0006386=Reactome:REACT_63, GO:0006385=Reactome:REACT_756, GO:0005736=GO_REF:0000019, GO:0003899=GO_REF:0000037, GO:0006363=Reactome:REACT_1074, GO:0006362=Reactome:REACT_2204, GO:0006361=Reactome:REACT_1974, GO:0006360=Reactome:REACT_1309, GO:0005654=Reactome:REACT_2228, GO:0006383=Reactome:REACT_1371, GO:0003677=GO_REF:0000002} Q9Y2S0 DNA-directed RNA polymerases I and III subunit RPAC2 protein 20130213 {GO:0010467=TAS, GO:0006386=TAS, GO:0006385=TAS, GO:0005736=IEA, GO:0003899=IEA, GO:0006363=TAS, GO:0006362=TAS, GO:0006361=TAS, GO:0006360=TAS, GO:0005654=TAS, GO:0006383=TAS, GO:0003677=IEA} gene expression, termination of RNA polymerase I transcription, termination of RNA polymerase III transcription, transcription elongation from RNA polymerase I promoter, transcription elongation from RNA polymerase III promoter, transcription from RNA polymerase I promoter, transcription from RNA polymerase III promoter, transcription initiation from RNA polymerase I promoter DNA-directed RNA polymerase I complex, nucleoplasm DNA binding, DNA-directed RNA polymerase activity Human POLR1E HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0030054=GO_REF:0000052, GO:0003899=GO_REF:0000037, GO:0009303=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000002} Q9GZS1 DNA-directed RNA polymerase I subunit RPA49 protein 20101115 {GO:0005737=IDA, GO:0030054=IDA, GO:0003899=IEA, GO:0009303=ISS, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA} rRNA transcription, transcription, DNA-dependent cell junction, cytoplasm, nucleolus, nucleus DNA binding, DNA-directed RNA polymerase activity Human POLR2A UniProtKB UniProtKB {GO:0005515=PMID:22264791, GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0022415=Reactome:REACT_6361, GO:0006368=Reactome:REACT_2089, GO:0006367=Reactome:REACT_1851, GO:0006366=Reactome:REACT_1366, GO:0005634=GO_REF:0000052, GO:0046872=GO_REF:0000037, GO:0003968=GO_REF:0000003, GO:0005665=PMID:9852112, GO:0016032=Reactome:REACT_6256, GO:0031625=PMID:17996703, GO:0006355=PMID:7622068, GO:0003899=GO_REF:0000003, GO:0005730=GO_REF:0000052, GO:0006370=Reactome:REACT_1470, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000002, GO:0050434=Reactome:REACT_6162, GO:0006281=Reactome:REACT_216, GO:0004672=PMID:9852112, GO:0000398=Reactome:REACT_1753, GO:0006283=Reactome:REACT_1628, GO:0006468=PMID:9852112, GO:0005654=Reactome:REACT_12505, GO:0006289=Reactome:REACT_1826} Q6NX41 DNA-directed RNA polymerase protein 20130413 {GO:0005515=IPI, GO:0008380=TAS, GO:0010467=TAS, GO:0022415=TAS, GO:0006368=TAS, GO:0006367=TAS, GO:0006366=TAS, GO:0005634=IDA, GO:0046872=IEA, GO:0003968=IEA, GO:0005665=IDA, GO:0016032=TAS, GO:0031625=IPI, GO:0006355=NAS, GO:0003899=IEA, GO:0005730=IDA, GO:0006370=TAS, GO:0003677=IEA, GO:0006351=IEA, GO:0050434=TAS, GO:0006281=TAS, GO:0004672=IDA, GO:0000398=TAS, GO:0006283=TAS, GO:0006468=IDA, GO:0005654=TAS, GO:0006289=TAS} 7-methylguanosine mRNA capping, DNA repair, RNA splicing, gene expression, mRNA splicing, via spliceosome, nucleotide-excision repair, positive regulation of viral transcription, protein phosphorylation, regulation of transcription, DNA-dependent, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transcription-coupled nucleotide-excision repair, viral reproduction, viral reproductive process DNA-directed RNA polymerase II, core complex, nucleolus, nucleoplasm, nucleus DNA binding, DNA-directed RNA polymerase activity, RNA-directed RNA polymerase activity, metal ion binding, protein binding, protein kinase activity, ubiquitin protein ligase binding Human EC:2.7.7.6 POLR2B GOC UniProtKB {GO:0005515=PMID:17998332, GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0022415=Reactome:REACT_6361, GO:0006368=Reactome:REACT_2089, GO:0006367=Reactome:REACT_1851, GO:0006366=Reactome:REACT_1366, GO:0005634=GO_REF:0000052, GO:0046872=GO_REF:0000037, GO:0005665=PMID:9852112, GO:0016032=Reactome:REACT_6256, GO:0003899=GO_REF:0000003, GO:0005730=GO_REF:0000052, GO:0032549=GO_REF:0000002, GO:0006370=Reactome:REACT_1470, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000002, GO:0050434=Reactome:REACT_6162, GO:0004672=PMID:9852112, GO:0006281=Reactome:REACT_216, GO:0000398=Reactome:REACT_1753, GO:0006283=Reactome:REACT_1628, GO:0003682=GO_REF:0000019, GO:0006468=PMID:9852112, GO:0005654=Reactome:REACT_12505, GO:0006289=Reactome:REACT_1826} P30876 DNA-directed RNA polymerase II subunit RPB2 protein 20130413 {GO:0005515=IPI, GO:0008380=TAS, GO:0010467=TAS, GO:0022415=TAS, GO:0006368=TAS, GO:0006367=TAS, GO:0006366=TAS, GO:0005634=IDA, GO:0046872=IEA, GO:0005665=IDA, GO:0016032=TAS, GO:0003899=IEA, GO:0005730=IDA, GO:0032549=IEA, GO:0006370=TAS, GO:0003677=IEA, GO:0006351=IEA, GO:0050434=TAS, GO:0004672=IDA, GO:0006281=TAS, GO:0000398=TAS, GO:0006283=TAS, GO:0003682=IEA, GO:0006468=IDA, GO:0005654=TAS, GO:0006289=TAS} 7-methylguanosine mRNA capping, DNA repair, RNA splicing, gene expression, mRNA splicing, via spliceosome, nucleotide-excision repair, positive regulation of viral transcription, protein phosphorylation, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transcription-coupled nucleotide-excision repair, viral reproduction, viral reproductive process DNA-directed RNA polymerase II, core complex, nucleolus, nucleoplasm, nucleus DNA binding, DNA-directed RNA polymerase activity, chromatin binding, metal ion binding, protein binding, protein kinase activity, ribonucleoside binding Human POLR2C HPA UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006368=Reactome:REACT_2089, GO:0006367=Reactome:REACT_1851, GO:0006366=Reactome:REACT_1366, GO:0003899=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0006370=Reactome:REACT_1470, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000002, GO:0050434=Reactome:REACT_6162, GO:0005737=GO_REF:0000019, GO:0006281=Reactome:REACT_216, GO:0000398=Reactome:REACT_1753, GO:0006283=Reactome:REACT_1628, GO:0015630=GO_REF:0000052, GO:0046983=GO_REF:0000002, GO:0005665=PMID:9852112, GO:0016032=Reactome:REACT_6256, GO:0005654=Reactome:REACT_12505, GO:0006289=Reactome:REACT_1826} P19387 DNA-directed RNA polymerase II subunit RPB3 protein 20110516 {GO:0008380=TAS, GO:0022415=TAS, GO:0010467=TAS, GO:0006368=TAS, GO:0006367=TAS, GO:0006366=TAS, GO:0003899=IEA, GO:0005730=IDA, GO:0006370=TAS, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA, GO:0050434=TAS, GO:0005737=IEA, GO:0006281=TAS, GO:0000398=TAS, GO:0006283=TAS, GO:0015630=IDA, GO:0046983=IEA, GO:0005665=IDA, GO:0016032=TAS, GO:0005654=TAS, GO:0006289=TAS} 7-methylguanosine mRNA capping, DNA repair, RNA splicing, gene expression, mRNA splicing, via spliceosome, nucleotide-excision repair, positive regulation of viral transcription, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transcription-coupled nucleotide-excision repair, viral reproduction, viral reproductive process DNA-directed RNA polymerase II, core complex, cytoplasm, microtubule cytoskeleton, nucleolus, nucleoplasm, nucleus DNA binding, DNA-directed RNA polymerase activity, protein dimerization activity Human POLR2D GOC UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006368=Reactome:REACT_2089, GO:0006367=Reactome:REACT_1851, GO:0006366=Reactome:REACT_1366, GO:0003899=PMID:9528765, GO:0006370=Reactome:REACT_1470, GO:0005634=PMID:9852112, GO:0006351=GO_REF:0000002, GO:0050434=Reactome:REACT_6162, GO:0004672=PMID:9852112, GO:0006281=Reactome:REACT_216, GO:0000166=GO_REF:0000002, GO:0000398=Reactome:REACT_1753, GO:0006283=Reactome:REACT_1628, GO:0005665=PMID:9852112, GO:0016032=Reactome:REACT_6256, GO:0006468=PMID:9852112, GO:0005654=Reactome:REACT_12505, GO:0006289=Reactome:REACT_1826} O15514 DNA-directed RNA polymerase II subunit RPB4 protein 20130413 {GO:0008380=TAS, GO:0022415=TAS, GO:0010467=TAS, GO:0006368=TAS, GO:0006367=TAS, GO:0006366=TAS, GO:0003899=IMP, GO:0006370=TAS, GO:0005634=IDA, GO:0006351=IEA, GO:0050434=TAS, GO:0004672=IDA, GO:0006281=TAS, GO:0000166=IEA, GO:0000398=TAS, GO:0006283=TAS, GO:0005665=IDA, GO:0016032=TAS, GO:0006468=IDA, GO:0005654=TAS, GO:0006289=TAS} 7-methylguanosine mRNA capping, DNA repair, RNA splicing, gene expression, mRNA splicing, via spliceosome, nucleotide-excision repair, positive regulation of viral transcription, protein phosphorylation, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transcription-coupled nucleotide-excision repair, viral reproduction, viral reproductive process DNA-directed RNA polymerase II, core complex, nucleoplasm, nucleus DNA-directed RNA polymerase activity, nucleotide binding, protein kinase activity Human POLR2E GOC UniProtKB {GO:0005515=PMID:15923622, GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0022415=Reactome:REACT_6361, GO:0006368=Reactome:REACT_2089, GO:0006386=Reactome:REACT_63, GO:0006367=Reactome:REACT_1851, GO:0006385=Reactome:REACT_756, GO:0006366=Reactome:REACT_1366, GO:0005634=PMID:9852112, GO:0006383=Reactome:REACT_1371, GO:0005665=PMID:9852112, GO:0016032=Reactome:REACT_6256, GO:0003899=GO_REF:0000037, GO:0006370=Reactome:REACT_1470, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000002, GO:0050434=Reactome:REACT_6162, GO:0006281=Reactome:REACT_216, GO:0004672=PMID:9852112, GO:0006283=Reactome:REACT_1628, GO:0000398=Reactome:REACT_1753, GO:0019048=GO_REF:0000037, GO:0006468=PMID:9852112, GO:0005654=Reactome:REACT_12505, GO:0006289=Reactome:REACT_1826} P19388 DNA-directed RNA polymerases I, II, and III subunit RPABC1 protein 20130413 {GO:0005515=IPI, GO:0008380=TAS, GO:0010467=TAS, GO:0022415=TAS, GO:0006368=TAS, GO:0006386=TAS, GO:0006367=TAS, GO:0006385=TAS, GO:0006366=TAS, GO:0005634=IDA, GO:0006383=TAS, GO:0005665=IDA, GO:0016032=TAS, GO:0003899=IEA, GO:0006370=TAS, GO:0003677=IEA, GO:0006351=IEA, GO:0050434=TAS, GO:0006281=TAS, GO:0004672=IDA, GO:0006283=TAS, GO:0000398=TAS, GO:0019048=IEA, GO:0006468=IDA, GO:0005654=TAS, GO:0006289=TAS} 7-methylguanosine mRNA capping, DNA repair, RNA splicing, gene expression, mRNA splicing, via spliceosome, nucleotide-excision repair, positive regulation of viral transcription, protein phosphorylation, termination of RNA polymerase III transcription, transcription elongation from RNA polymerase II promoter, transcription elongation from RNA polymerase III promoter, transcription from RNA polymerase II promoter, transcription from RNA polymerase III promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transcription-coupled nucleotide-excision repair, viral reproduction, viral reproductive process, virus-host interaction DNA-directed RNA polymerase II, core complex, nucleoplasm, nucleus DNA binding, DNA-directed RNA polymerase activity, protein binding, protein kinase activity Human POLR2F GOC UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0022415=Reactome:REACT_6361, GO:0006368=Reactome:REACT_2089, GO:0006386=Reactome:REACT_63, GO:0006367=Reactome:REACT_1851, GO:0006385=Reactome:REACT_756, GO:0006366=Reactome:REACT_1366, GO:0005634=GO_REF:0000052, GO:0006383=Reactome:REACT_1371, GO:0005665=PMID:9852112, GO:0016032=Reactome:REACT_6256, GO:0030880=GO_REF:0000002, GO:0003899=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0006370=Reactome:REACT_1470, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000002, GO:0050434=Reactome:REACT_6162, GO:0006281=Reactome:REACT_216, GO:0004672=PMID:9852112, GO:0006283=Reactome:REACT_1628, GO:0000398=Reactome:REACT_1753, GO:0006468=PMID:9852112, GO:0005654=Reactome:REACT_12505, GO:0006289=Reactome:REACT_1826} P61218 DNA-directed RNA polymerases I, II, and III subunit RPABC2 protein 20130413 {GO:0008380=TAS, GO:0010467=TAS, GO:0022415=TAS, GO:0006368=TAS, GO:0006386=TAS, GO:0006367=TAS, GO:0006385=TAS, GO:0006366=TAS, GO:0005634=IDA, GO:0006383=TAS, GO:0005665=IDA, GO:0016032=TAS, GO:0030880=IEA, GO:0003899=IEA, GO:0005730=IDA, GO:0006370=TAS, GO:0003677=IEA, GO:0006351=IEA, GO:0050434=TAS, GO:0006281=TAS, GO:0004672=IDA, GO:0006283=TAS, GO:0000398=TAS, GO:0006468=IDA, GO:0005654=TAS, GO:0006289=TAS} 7-methylguanosine mRNA capping, DNA repair, RNA splicing, gene expression, mRNA splicing, via spliceosome, nucleotide-excision repair, positive regulation of viral transcription, protein phosphorylation, termination of RNA polymerase III transcription, transcription elongation from RNA polymerase II promoter, transcription elongation from RNA polymerase III promoter, transcription from RNA polymerase II promoter, transcription from RNA polymerase III promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transcription-coupled nucleotide-excision repair, viral reproduction, viral reproductive process DNA-directed RNA polymerase II, core complex, RNA polymerase complex, nucleolus, nucleoplasm, nucleus DNA binding, DNA-directed RNA polymerase activity, protein kinase activity Human POLR2G GOC UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006368=Reactome:REACT_2089, GO:0006367=Reactome:REACT_1851, GO:0006366=Reactome:REACT_1366, GO:0003899=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0006370=Reactome:REACT_1470, GO:0006915=GO_REF:0000019, GO:0005634=PMID:9852112, GO:0006351=GO_REF:0000002, GO:0050434=Reactome:REACT_6162, GO:0004672=PMID:9852112, GO:0006281=Reactome:REACT_216, GO:0000398=Reactome:REACT_1753, GO:0006283=Reactome:REACT_1628, GO:0005665=PMID:9852112, GO:0016032=Reactome:REACT_6256, GO:0006468=PMID:9852112, GO:0005654=Reactome:REACT_12505, GO:0006289=Reactome:REACT_1826} P62487 DNA-directed RNA polymerase II subunit RPB7 protein 20130413 {GO:0008380=TAS, GO:0022415=TAS, GO:0010467=TAS, GO:0006368=TAS, GO:0006367=TAS, GO:0006366=TAS, GO:0003899=IEA, GO:0003723=IEA, GO:0006370=TAS, GO:0006915=IEA, GO:0005634=IDA, GO:0006351=IEA, GO:0050434=TAS, GO:0004672=IDA, GO:0006281=TAS, GO:0000398=TAS, GO:0006283=TAS, GO:0005665=IDA, GO:0016032=TAS, GO:0006468=IDA, GO:0005654=TAS, GO:0006289=TAS} 7-methylguanosine mRNA capping, DNA repair, RNA splicing, apoptotic process, gene expression, mRNA splicing, via spliceosome, nucleotide-excision repair, positive regulation of viral transcription, protein phosphorylation, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transcription-coupled nucleotide-excision repair, viral reproduction, viral reproductive process DNA-directed RNA polymerase II, core complex, nucleoplasm, nucleus DNA-directed RNA polymerase activity, RNA binding, protein kinase activity Human POLR2H GOC UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006368=Reactome:REACT_2089, GO:0006386=Reactome:REACT_63, GO:0006367=Reactome:REACT_1851, GO:0006385=Reactome:REACT_756, GO:0006366=Reactome:REACT_1366, GO:0006363=Reactome:REACT_1074, GO:0006362=Reactome:REACT_2204, GO:0006361=Reactome:REACT_1974, GO:0005634=GO_REF:0000052, GO:0006360=Reactome:REACT_1309, GO:0006383=Reactome:REACT_1371, GO:0005737=GO_REF:0000052, GO:0005665=PMID:9852112, GO:0016032=Reactome:REACT_6256, GO:0003899=GO_REF:0000029, GO:0005730=GO_REF:0000039, GO:0006370=Reactome:REACT_1470, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000002, GO:0050434=Reactome:REACT_6162, GO:0006281=Reactome:REACT_216, GO:0004672=PMID:9852112, GO:0000398=Reactome:REACT_1753, GO:0006283=Reactome:REACT_1628, GO:0006468=PMID:9852112, GO:0005654=Reactome:REACT_12505, GO:0008270=GO_REF:0000029, GO:0006289=Reactome:REACT_1826} P52434 DNA-directed RNA polymerases I, II, and III subunit RPABC3 protein 20130413 {GO:0008380=TAS, GO:0022415=TAS, GO:0010467=TAS, GO:0006368=TAS, GO:0006386=TAS, GO:0006367=TAS, GO:0006385=TAS, GO:0006366=TAS, GO:0006363=TAS, GO:0006362=TAS, GO:0006361=TAS, GO:0005634=IDA, GO:0006360=TAS, GO:0006383=TAS, GO:0005737=IDA, GO:0005665=IDA, GO:0016032=TAS, GO:0003899=NAS, GO:0005730=IEA, GO:0006370=TAS, GO:0003677=IEA, GO:0006351=IEA, GO:0050434=TAS, GO:0006281=TAS, GO:0004672=IDA, GO:0000398=TAS, GO:0006283=TAS, GO:0006468=IDA, GO:0005654=TAS, GO:0008270=NAS, GO:0006289=TAS} 7-methylguanosine mRNA capping, DNA repair, RNA splicing, gene expression, mRNA splicing, via spliceosome, nucleotide-excision repair, positive regulation of viral transcription, protein phosphorylation, termination of RNA polymerase I transcription, termination of RNA polymerase III transcription, transcription elongation from RNA polymerase I promoter, transcription elongation from RNA polymerase II promoter, transcription elongation from RNA polymerase III promoter, transcription from RNA polymerase I promoter, transcription from RNA polymerase II promoter, transcription from RNA polymerase III promoter, transcription initiation from RNA polymerase I promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transcription-coupled nucleotide-excision repair, viral reproduction, viral reproductive process DNA-directed RNA polymerase II, core complex, cytoplasm, nucleolus, nucleoplasm, nucleus DNA binding, DNA-directed RNA polymerase activity, protein kinase activity, zinc ion binding Human POLR2I GOC UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006368=Reactome:REACT_2089, GO:0006367=Reactome:REACT_1851, GO:0006366=Reactome:REACT_1366, GO:0003899=GO_REF:0000037, GO:0006370=Reactome:REACT_1470, GO:0005634=PMID:9852112, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000002, GO:0050434=Reactome:REACT_6162, GO:0004672=PMID:9852112, GO:0006281=Reactome:REACT_216, GO:0000398=Reactome:REACT_1753, GO:0006283=Reactome:REACT_1628, GO:0005665=PMID:9852112, GO:0016032=Reactome:REACT_6256, GO:0006468=PMID:9852112, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_12505, GO:0006289=Reactome:REACT_1826} P36954 DNA-directed RNA polymerase II subunit RPB9 protein 20130413 {GO:0008380=TAS, GO:0022415=TAS, GO:0010467=TAS, GO:0006368=TAS, GO:0006367=TAS, GO:0006366=TAS, GO:0003899=IEA, GO:0006370=TAS, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA, GO:0050434=TAS, GO:0004672=IDA, GO:0006281=TAS, GO:0000398=TAS, GO:0006283=TAS, GO:0005665=IDA, GO:0016032=TAS, GO:0006468=IDA, GO:0008270=IEA, GO:0005654=TAS, GO:0006289=TAS} 7-methylguanosine mRNA capping, DNA repair, RNA splicing, gene expression, mRNA splicing, via spliceosome, nucleotide-excision repair, positive regulation of viral transcription, protein phosphorylation, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transcription-coupled nucleotide-excision repair, viral reproduction, viral reproductive process DNA-directed RNA polymerase II, core complex, nucleoplasm, nucleus DNA binding, DNA-directed RNA polymerase activity, protein kinase activity, zinc ion binding Human POLR2J GOC UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:10783144, GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006368=Reactome:REACT_2089, GO:0006367=Reactome:REACT_1851, GO:0006366=Reactome:REACT_1366, GO:0003899=GO_REF:0000037, GO:0006370=Reactome:REACT_1470, GO:0005634=PMID:9852112, GO:0003677=GO_REF:0000002, GO:0050434=Reactome:REACT_6162, GO:0004672=PMID:9852112, GO:0006281=Reactome:REACT_216, GO:0000398=Reactome:REACT_1753, GO:0006283=Reactome:REACT_1628, GO:0030275=PMID:10783144, GO:0005665=PMID:9852112, GO:0016032=Reactome:REACT_6256, GO:0006468=PMID:9852112, GO:0005654=Reactome:REACT_12505, GO:0006289=Reactome:REACT_1826} P52435 DNA-directed RNA polymerase II subunit RPB11-a protein 20130413 {GO:0008380=TAS, GO:0005515=IPI, GO:0022415=TAS, GO:0010467=TAS, GO:0006368=TAS, GO:0006367=TAS, GO:0006366=TAS, GO:0003899=IEA, GO:0006370=TAS, GO:0005634=IDA, GO:0003677=IEA, GO:0050434=TAS, GO:0004672=IDA, GO:0006281=TAS, GO:0000398=TAS, GO:0006283=TAS, GO:0030275=IPI, GO:0005665=IDA, GO:0016032=TAS, GO:0006468=IDA, GO:0005654=TAS, GO:0006289=TAS} 7-methylguanosine mRNA capping, DNA repair, RNA splicing, gene expression, mRNA splicing, via spliceosome, nucleotide-excision repair, positive regulation of viral transcription, protein phosphorylation, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, transcription-coupled nucleotide-excision repair, viral reproduction, viral reproductive process DNA-directed RNA polymerase II, core complex, nucleoplasm, nucleus DNA binding, DNA-directed RNA polymerase activity, LRR domain binding, protein binding, protein kinase activity Human POLR2J2 UniProtKB UniProtKB {GO:0003899=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000002} Q9GZM3 DNA-directed RNA polymerase II subunit RPB11-b1 protein 20130413 {GO:0003899=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} transcription, DNA-dependent nucleus DNA binding, DNA-directed RNA polymerase activity Human UniProtKB-SubCell:SL-0191 POLR2J3 UniProtKB UniProtKB {GO:0035556=GO_REF:0000002, GO:0003899=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000002} Q9H1A7 DNA-directed RNA polymerase II subunit RPB11-b2 protein 20130413 {GO:0035556=IEA, GO:0003899=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} intracellular signal transduction, transcription, DNA-dependent nucleus DNA binding, DNA-directed RNA polymerase activity Human UniProtKB-SubCell:SL-0191 POLR2K Reactome UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0022415=Reactome:REACT_6361, GO:0006368=Reactome:REACT_2089, GO:0006386=Reactome:REACT_63, GO:0006367=Reactome:REACT_1851, GO:0006385=Reactome:REACT_756, GO:0006366=Reactome:REACT_1366, GO:0006363=Reactome:REACT_1074, GO:0006362=Reactome:REACT_2204, GO:0006361=Reactome:REACT_1974, GO:0006360=Reactome:REACT_1309, GO:0006383=Reactome:REACT_1371, GO:0016032=Reactome:REACT_6256, GO:0006356=PMID:7651387, GO:0003899=GO_REF:0000037, GO:0006370=Reactome:REACT_1470, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000002, GO:0050434=Reactome:REACT_6162, GO:0006281=Reactome:REACT_216, GO:0006283=Reactome:REACT_1628, GO:0000398=Reactome:REACT_1753, GO:0005654=Reactome:REACT_12505, GO:0008270=PMID:7651387, GO:0006289=Reactome:REACT_1826} P53803 DNA-directed RNA polymerases I, II, and III subunit RPABC4 protein 20130213 {GO:0008380=TAS, GO:0010467=TAS, GO:0022415=TAS, GO:0006368=TAS, GO:0006386=TAS, GO:0006367=TAS, GO:0006385=TAS, GO:0006366=TAS, GO:0006363=TAS, GO:0006362=TAS, GO:0006361=TAS, GO:0006360=TAS, GO:0006383=TAS, GO:0016032=TAS, GO:0006356=TAS, GO:0003899=IEA, GO:0006370=TAS, GO:0003677=IEA, GO:0006351=IEA, GO:0050434=TAS, GO:0006281=TAS, GO:0006283=TAS, GO:0000398=TAS, GO:0005654=TAS, GO:0008270=TAS, GO:0006289=TAS} 7-methylguanosine mRNA capping, DNA repair, RNA splicing, gene expression, mRNA splicing, via spliceosome, nucleotide-excision repair, positive regulation of viral transcription, regulation of transcription from RNA polymerase I promoter, termination of RNA polymerase I transcription, termination of RNA polymerase III transcription, transcription elongation from RNA polymerase I promoter, transcription elongation from RNA polymerase II promoter, transcription elongation from RNA polymerase III promoter, transcription from RNA polymerase I promoter, transcription from RNA polymerase II promoter, transcription from RNA polymerase III promoter, transcription initiation from RNA polymerase I promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transcription-coupled nucleotide-excision repair, viral reproduction, viral reproductive process nucleoplasm DNA binding, DNA-directed RNA polymerase activity, zinc ion binding Human POLR2L GOC UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0022415=Reactome:REACT_6361, GO:0006368=Reactome:REACT_2089, GO:0006386=Reactome:REACT_63, GO:0006367=Reactome:REACT_1851, GO:0006385=Reactome:REACT_756, GO:0006366=Reactome:REACT_1366, GO:0005634=PMID:9852112, GO:0006383=Reactome:REACT_1371, GO:0005665=PMID:9852112, GO:0016032=Reactome:REACT_6256, GO:0006356=PMID:8786124, GO:0003899=GO_REF:0000037, GO:0006370=Reactome:REACT_1470, GO:0003677=GO_REF:0000002, GO:0050434=Reactome:REACT_6162, GO:0006281=Reactome:REACT_216, GO:0004672=PMID:9852112, GO:0006283=Reactome:REACT_1628, GO:0000398=Reactome:REACT_1753, GO:0005654=Reactome:REACT_12505, GO:0008270=GO_REF:0000002, GO:0006468=PMID:9852112, GO:0006289=Reactome:REACT_1826} P62875 DNA-directed RNA polymerases I, II, and III subunit RPABC5 protein 20130413 {GO:0008380=TAS, GO:0010467=TAS, GO:0022415=TAS, GO:0006368=TAS, GO:0006386=TAS, GO:0006367=TAS, GO:0006385=TAS, GO:0006366=TAS, GO:0005634=IDA, GO:0006383=TAS, GO:0005665=IDA, GO:0016032=TAS, GO:0006356=TAS, GO:0003899=IEA, GO:0006370=TAS, GO:0003677=IEA, GO:0050434=TAS, GO:0006281=TAS, GO:0004672=IDA, GO:0006283=TAS, GO:0000398=TAS, GO:0005654=TAS, GO:0008270=IEA, GO:0006468=IDA, GO:0006289=TAS} 7-methylguanosine mRNA capping, DNA repair, RNA splicing, gene expression, mRNA splicing, via spliceosome, nucleotide-excision repair, positive regulation of viral transcription, protein phosphorylation, regulation of transcription from RNA polymerase I promoter, termination of RNA polymerase III transcription, transcription elongation from RNA polymerase II promoter, transcription elongation from RNA polymerase III promoter, transcription from RNA polymerase II promoter, transcription from RNA polymerase III promoter, transcription initiation from RNA polymerase II promoter, transcription-coupled nucleotide-excision repair, viral reproduction, viral reproductive process DNA-directed RNA polymerase II, core complex, nucleoplasm, nucleus DNA binding, DNA-directed RNA polymerase activity, protein kinase activity, zinc ion binding Human POLR2M LIFEdb UniProtKB {GO:0003899=GO_REF:0000037, GO:0016591=PMID:22231121, GO:0043025=GO_REF:0000019, GO:0051685=GO_REF:0000019, GO:0005635=GO_REF:0000054} P0CAP2 DNA-directed RNA polymerase II subunit GRINL1A protein 20100607 {GO:0003899=IEA, GO:0016591=IDA, GO:0043025=IEA, GO:0051685=IEA, GO:0005635=IDA} maintenance of ER location DNA-directed RNA polymerase II, holoenzyme, neuronal cell body, nuclear envelope DNA-directed RNA polymerase activity Human POLR3A HPA UniProtKB {GO:0010467=Reactome:REACT_71, GO:0032728=PMID:19609254, GO:0006386=Reactome:REACT_63, GO:0006385=Reactome:REACT_756, GO:0003899=PMID:9331371, GO:0005730=GO_REF:0000052, GO:0032549=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000002, GO:0006383=Reactome:REACT_1371, GO:0006351=PMID:9331371, GO:0051607=GO_REF:0000037, GO:0003682=GO_REF:0000019, GO:0045087=PMID:19609254, GO:0005666=GO_REF:0000029, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_1779} O14802 DNA-directed RNA polymerase III subunit RPC1 protein 20110516 {GO:0010467=TAS, GO:0032728=IMP, GO:0006386=TAS, GO:0006385=TAS, GO:0003899=NAS, GO:0005730=IDA, GO:0032549=IEA, GO:0005634=IDA, GO:0003677=IEA, GO:0006383=TAS, GO:0006351=NAS, GO:0051607=IEA, GO:0003682=IEA, GO:0045087=IMP, GO:0005666=NAS, GO:0008270=IEA, GO:0005654=TAS} defense response to virus, gene expression, innate immune response, positive regulation of interferon-beta production, termination of RNA polymerase III transcription, transcription elongation from RNA polymerase III promoter, transcription from RNA polymerase III promoter, transcription, DNA-dependent DNA-directed RNA polymerase III complex, nucleolus, nucleoplasm, nucleus DNA binding, DNA-directed RNA polymerase activity, chromatin binding, ribonucleoside binding, zinc ion binding NOT Human POLR3B Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0032728=PMID:19609254, GO:0006386=Reactome:REACT_63, GO:0006385=Reactome:REACT_756, GO:0003899=GO_REF:0000003, GO:0032549=GO_REF:0000002, GO:0003677=GO_REF:0000002, GO:0006383=Reactome:REACT_1371, GO:0006351=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0051607=GO_REF:0000037, GO:0045089=PMID:19609254, GO:0045087=GO_REF:0000037, GO:0005654=Reactome:REACT_1779} Q9NW08 DNA-directed RNA polymerase III subunit RPC2 protein 20130213 {GO:0010467=TAS, GO:0032728=IMP, GO:0006386=TAS, GO:0006385=TAS, GO:0003899=IEA, GO:0032549=IEA, GO:0003677=IEA, GO:0006383=TAS, GO:0006351=IEA, GO:0046872=IEA, GO:0051607=IEA, GO:0045089=IMP, GO:0045087=IEA, GO:0005654=TAS} defense response to virus, gene expression, innate immune response, positive regulation of innate immune response, positive regulation of interferon-beta production, termination of RNA polymerase III transcription, transcription elongation from RNA polymerase III promoter, transcription from RNA polymerase III promoter, transcription, DNA-dependent nucleoplasm DNA binding, DNA-directed RNA polymerase activity, metal ion binding, ribonucleoside binding Human POLR3C HPA UniProtKB {GO:0010467=Reactome:REACT_71, GO:0032728=PMID:19609254, GO:0006386=Reactome:REACT_63, GO:0006385=Reactome:REACT_756, GO:0003899=GO_REF:0000037, GO:0006359=PMID:9171375, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000002, GO:0006383=Reactome:REACT_1371, GO:0006351=GO_REF:0000002, GO:0051607=GO_REF:0000037, GO:0045089=PMID:19609254, GO:0045087=GO_REF:0000037, GO:0005666=PMID:9171375, GO:0005654=Reactome:REACT_1779} Q9BUI4 DNA-directed RNA polymerase III subunit RPC3 protein 20111111 {GO:0010467=TAS, GO:0032728=IMP, GO:0006386=TAS, GO:0006385=TAS, GO:0003899=IEA, GO:0006359=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0006383=TAS, GO:0006351=IEA, GO:0051607=IEA, GO:0045089=IMP, GO:0045087=IEA, GO:0005666=TAS, GO:0005654=TAS} defense response to virus, gene expression, innate immune response, positive regulation of innate immune response, positive regulation of interferon-beta production, regulation of transcription from RNA polymerase III promoter, termination of RNA polymerase III transcription, transcription elongation from RNA polymerase III promoter, transcription from RNA polymerase III promoter, transcription, DNA-dependent DNA-directed RNA polymerase III complex, nucleolus, nucleoplasm, nucleus DNA binding, DNA-directed RNA polymerase activity NOT Human POLR3D Reactome UniProtKB {GO:0032728=PMID:19631370, GO:0010467=Reactome:REACT_71, GO:0006386=Reactome:REACT_63, GO:0006385=Reactome:REACT_756, GO:0003899=GO_REF:0000037, GO:0003677=GO_REF:0000002, GO:0006383=Reactome:REACT_1371, GO:0051607=GO_REF:0000037, GO:0045089=PMID:19631370, GO:0003682=GO_REF:0000019, GO:0045087=GO_REF:0000037, GO:0005666=GO_REF:0000002, GO:0005654=Reactome:REACT_1779} P05423 DNA-directed RNA polymerase III subunit RPC4 protein 20130213 {GO:0032728=IDA, GO:0010467=TAS, GO:0006386=TAS, GO:0006385=TAS, GO:0003899=IEA, GO:0003677=IEA, GO:0006383=TAS, GO:0051607=IEA, GO:0045089=IDA, GO:0003682=IEA, GO:0045087=IEA, GO:0005666=IEA, GO:0005654=TAS} defense response to virus, gene expression, innate immune response, positive regulation of innate immune response, positive regulation of interferon-beta production, termination of RNA polymerase III transcription, transcription elongation from RNA polymerase III promoter, transcription from RNA polymerase III promoter DNA-directed RNA polymerase III complex, nucleoplasm DNA binding, DNA-directed RNA polymerase activity, chromatin binding Human POLR3E HPA UniProtKB {GO:0010467=Reactome:REACT_71, GO:0006386=Reactome:REACT_63, GO:0051607=GO_REF:0000037, GO:0006385=Reactome:REACT_756, GO:0003899=GO_REF:0000037, GO:0045087=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005654=Reactome:REACT_1779, GO:0005634=GO_REF:0000052, GO:0006383=Reactome:REACT_1371, GO:0006351=GO_REF:0000002} Q9NVU0 DNA-directed RNA polymerase III subunit RPC5 protein 20111111 {GO:0010467=TAS, GO:0006386=TAS, GO:0051607=IEA, GO:0006385=TAS, GO:0003899=IEA, GO:0045087=IEA, GO:0005730=IDA, GO:0005654=TAS, GO:0005634=IDA, GO:0006383=TAS, GO:0006351=IEA} defense response to virus, gene expression, innate immune response, termination of RNA polymerase III transcription, transcription elongation from RNA polymerase III promoter, transcription from RNA polymerase III promoter, transcription, DNA-dependent nucleolus, nucleoplasm, nucleus DNA-directed RNA polymerase activity NOT Human POLR3F IntAct UniProtKB {GO:0005515=PMID:17612402, GO:0032728=PMID:19631370, GO:0010467=Reactome:REACT_71, GO:0006386=Reactome:REACT_63, GO:0006385=Reactome:REACT_756, GO:0003899=PMID:9171375, GO:0006359=PMID:9171375, GO:0003677=GO_REF:0000002, GO:0006383=Reactome:REACT_1371, GO:0051607=GO_REF:0000037, GO:0045089=PMID:19631370, GO:0045087=GO_REF:0000037, GO:0005666=PMID:10623476, GO:0005654=Reactome:REACT_1779} Q9H1D9 DNA-directed RNA polymerase III subunit RPC6 protein 20130415 {GO:0005515=IPI, GO:0032728=IMP, GO:0010467=TAS, GO:0006386=TAS, GO:0006385=TAS, GO:0003899=NAS, GO:0006359=NAS, GO:0003677=IEA, GO:0006383=TAS, GO:0051607=IEA, GO:0045089=IMP, GO:0045087=IEA, GO:0005666=NAS, GO:0005654=TAS} defense response to virus, gene expression, innate immune response, positive regulation of innate immune response, positive regulation of interferon-beta production, regulation of transcription from RNA polymerase III promoter, termination of RNA polymerase III transcription, transcription elongation from RNA polymerase III promoter, transcription from RNA polymerase III promoter DNA-directed RNA polymerase III complex, nucleoplasm DNA binding, DNA-directed RNA polymerase activity, protein binding Human UniProtKB:Q12796 POLR3G Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0032728=PMID:19609254, GO:0006386=Reactome:REACT_63, GO:0051607=GO_REF:0000037, GO:0006385=Reactome:REACT_756, GO:0045089=PMID:19609254, GO:0003899=GO_REF:0000037, GO:0006359=PMID:9171375, GO:0045087=GO_REF:0000037, GO:0005666=PMID:9171375, GO:0005654=Reactome:REACT_1779, GO:0006383=Reactome:REACT_1371} O15318 DNA-directed RNA polymerase III subunit RPC7 protein 20130301 {GO:0010467=TAS, GO:0032728=IMP, GO:0006386=TAS, GO:0051607=IEA, GO:0006385=TAS, GO:0045089=IMP, GO:0003899=IEA, GO:0006359=TAS, GO:0045087=IEA, GO:0005666=TAS, GO:0005654=TAS, GO:0006383=TAS} defense response to virus, gene expression, innate immune response, positive regulation of innate immune response, positive regulation of interferon-beta production, regulation of transcription from RNA polymerase III promoter, termination of RNA polymerase III transcription, transcription elongation from RNA polymerase III promoter, transcription from RNA polymerase III promoter DNA-directed RNA polymerase III complex, nucleoplasm DNA-directed RNA polymerase activity Human POLR3GL Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0006386=Reactome:REACT_63, GO:0006385=Reactome:REACT_756, GO:0005654=Reactome:REACT_1779, GO:0006383=Reactome:REACT_1371} Q9BT43 DNA-directed RNA polymerase III subunit RPC7-like protein 20130301 {GO:0010467=TAS, GO:0006386=TAS, GO:0006385=TAS, GO:0005654=TAS, GO:0006383=TAS} gene expression, termination of RNA polymerase III transcription, transcription elongation from RNA polymerase III promoter, transcription from RNA polymerase III promoter nucleoplasm Human POLR3H HPA UniProtKB {GO:0010467=Reactome:REACT_71, GO:0005813=GO_REF:0000052, GO:0006386=Reactome:REACT_63, GO:0006385=Reactome:REACT_756, GO:0003899=PMID:12391170, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000002, GO:0006383=Reactome:REACT_1371, GO:0006351=GO_REF:0000002, GO:0043231=GO_REF:0000052, GO:0051607=GO_REF:0000037, GO:0006139=PMID:12391170, GO:0045087=GO_REF:0000037, GO:0005666=PMID:12391170, GO:0005654=Reactome:REACT_1779} Q9Y535 DNA-directed RNA polymerase III subunit RPC8 protein 20120912 {GO:0010467=TAS, GO:0005813=IDA, GO:0006386=TAS, GO:0006385=TAS, GO:0003899=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0006383=TAS, GO:0006351=IEA, GO:0043231=IDA, GO:0051607=IEA, GO:0006139=IDA, GO:0045087=IEA, GO:0005666=IDA, GO:0005654=TAS} defense response to virus, gene expression, innate immune response, nucleobase-containing compound metabolic process, termination of RNA polymerase III transcription, transcription elongation from RNA polymerase III promoter, transcription from RNA polymerase III promoter, transcription, DNA-dependent DNA-directed RNA polymerase III complex, centrosome, intracellular membrane-bounded organelle, nucleolus, nucleoplasm, nucleus DNA binding, DNA-directed RNA polymerase activity Human POLR3K Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0006386=Reactome:REACT_63, GO:0051607=GO_REF:0000037, GO:0006385=Reactome:REACT_756, GO:0003899=GO_REF:0000037, GO:0045087=GO_REF:0000037, GO:0005666=PMID:9869639, GO:0005654=Reactome:REACT_1779, GO:0008270=GO_REF:0000002, GO:0006383=Reactome:REACT_1371, GO:0003677=GO_REF:0000002} Q9Y2Y1 DNA-directed RNA polymerase III subunit RPC10 protein 20111104 {GO:0010467=TAS, GO:0006386=TAS, GO:0051607=IEA, GO:0006385=TAS, GO:0003899=IEA, GO:0045087=IEA, GO:0005666=TAS, GO:0005654=TAS, GO:0008270=IEA, GO:0006383=TAS, GO:0003677=IEA} defense response to virus, gene expression, innate immune response, termination of RNA polymerase III transcription, transcription elongation from RNA polymerase III promoter, transcription from RNA polymerase III promoter DNA-directed RNA polymerase III complex, nucleoplasm DNA binding, DNA-directed RNA polymerase activity, zinc ion binding Human POLRMT BHF-UCL UniProtKB {GO:0042645=PMID:18063578, GO:0005739=PMID:17337445, GO:0005515=PMID:17337445, GO:0010467=Reactome:REACT_71, GO:0003899=PMID:17337445, GO:0005759=Reactome:REACT_268, GO:0006391=Reactome:REACT_367, GO:0006390=PMID:17337445, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000002} O00411 DNA-directed RNA polymerase, mitochondrial protein 20090218 {GO:0042645=IDA, GO:0005739=IDA, GO:0005515=IPI, GO:0010467=TAS, GO:0003899=TAS, GO:0005759=TAS, GO:0006391=TAS, GO:0006390=TAS, GO:0003677=IEA, GO:0006351=IEA} gene expression, transcription from mitochondrial promoter, transcription initiation from mitochondrial promoter, transcription, DNA-dependent mitochondrial matrix, mitochondrial nucleoid, mitochondrion DNA binding, DNA-directed RNA polymerase activity, protein binding Human POM121 Reactome UniProtKB {GO:0022415=Reactome:REACT_6361, GO:0031965=GO_REF:0000039, GO:0005975=Reactome:REACT_474, GO:0019221=Reactome:REACT_25229, GO:0044281=Reactome:REACT_111217, GO:0005635=Reactome:REACT_115827, GO:0015031=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0010827=Reactome:REACT_6804, GO:0008645=Reactome:REACT_9441, GO:0015758=Reactome:REACT_212, GO:0005643=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0016032=Reactome:REACT_6256, GO:0051028=GO_REF:0000037} Q96HA1 Nuclear envelope pore membrane protein POM 121 protein 20130301 {GO:0022415=TAS, GO:0031965=IEA, GO:0005975=TAS, GO:0019221=TAS, GO:0044281=TAS, GO:0005635=TAS, GO:0015031=IEA, GO:0055085=TAS, GO:0010827=TAS, GO:0008645=TAS, GO:0015758=TAS, GO:0005643=IEA, GO:0005789=IEA, GO:0016032=TAS, GO:0051028=IEA} carbohydrate metabolic process, cytokine-mediated signaling pathway, glucose transport, hexose transport, mRNA transport, protein transport, regulation of glucose transport, small molecule metabolic process, transmembrane transport, viral reproduction, viral reproductive process endoplasmic reticulum membrane, nuclear envelope, nuclear membrane, nuclear pore Human POM121C UniProtKB UniProtKB {GO:0005515=PMID:17577209, GO:0031965=GO_REF:0000039, GO:0005643=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0051028=GO_REF:0000037, GO:0015031=GO_REF:0000037} A8CG34 Nuclear envelope pore membrane protein POM 121C protein 20090724 {GO:0005515=IPI, GO:0031965=IEA, GO:0005643=IEA, GO:0005789=IEA, GO:0051028=IEA, GO:0015031=IEA} mRNA transport, protein transport endoplasmic reticulum membrane, nuclear membrane, nuclear pore protein binding Human UniProtKB:Q9BQA5 POMC BHF-UCL UniProtKB {GO:0001664=PMID:19452503, GO:0033059=PMID:9620771, GO:0005102=PMID:9620771, GO:0007267=PMID:9620771, GO:0032720=PMID:10233018, GO:0032098=PMID:9620771, GO:0005576=Reactome:REACT_22289, GO:0006091=PMID:9620771, GO:0005615=PMID:9620771, GO:0070996=PMID:19743876, GO:0007165=PMID:9620771, GO:0005737=GO_REF:0000024, GO:0016486=Reactome:REACT_15452, GO:0005179=PMID:9620771, GO:0007218=GO_REF:0000037, GO:0031781=PMID:19743876, GO:0045944=PMID:18292087, GO:0031782=PMID:19743876, GO:0008217=GO_REF:0000024, GO:0030141=GO_REF:0000024, GO:0044267=Reactome:REACT_17015, GO:0034774=Reactome:REACT_15476} P01189 Pro-opiomelanocortin protein 20091203 {GO:0001664=IDA, GO:0033059=IMP, GO:0005102=IMP, GO:0007267=IMP, GO:0032720=IDA, GO:0032098=IMP, GO:0005576=TAS, GO:0006091=IMP, GO:0005615=IDA, GO:0070996=IPI, GO:0007165=IMP, GO:0005737=ISS, GO:0016486=TAS, GO:0005179=IMP, GO:0007218=IEA, GO:0031781=IPI, GO:0045944=IDA, GO:0031782=IPI, GO:0008217=ISS, GO:0030141=ISS, GO:0044267=TAS, GO:0034774=TAS} cell-cell signaling, cellular pigmentation, cellular protein metabolic process, generation of precursor metabolites and energy, negative regulation of tumor necrosis factor production, neuropeptide signaling pathway, peptide hormone processing, positive regulation of transcription from RNA polymerase II promoter, regulation of appetite, regulation of blood pressure, signal transduction cytoplasm, extracellular region, extracellular space, secretory granule, secretory granule lumen G-protein coupled receptor binding, hormone activity, receptor binding, type 1 melanocortin receptor binding, type 3 melanocortin receptor binding, type 4 melanocortin receptor binding Human UniProtKB:P32245 POMGNT1 MGI UniProtKB {GO:0008375=GO_REF:0000002, GO:0006493=PMID:11709191, GO:0000139=GO_REF:0000039, GO:0006486=GO_REF:0000002, GO:0047223=PMID:11742540, GO:0016021=GO_REF:0000037} Q8WZA1 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 protein 20060727 {GO:0008375=IEA, GO:0006493=IDA, GO:0000139=IEA, GO:0006486=IEA, GO:0047223=IDA, GO:0016021=IEA} protein O-linked glycosylation, protein glycosylation Golgi membrane, integral to membrane acetylglucosaminyltransferase activity, beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity Human POMP HPA UniProtKB {GO:0043248=PMID:17948026, GO:0000502=GO_REF:0000037, GO:0005783=GO_REF:0000037, GO:0031090=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005829=GO_REF:0000039} Q9Y244 Proteasome maturation protein protein 20101115 {GO:0043248=IMP, GO:0000502=IEA, GO:0005783=IEA, GO:0031090=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005829=IEA} proteasome assembly cytosol, endoplasmic reticulum, nucleolus, nucleus, organelle membrane, proteasome complex NOT Human POMT1 PINC UniProtKB {GO:0000030=PMID:10366449, GO:0001669=GO_REF:0000019, GO:0005783=PMID:10366449, GO:0005975=PMID:10366449, GO:0007275=PMID:10366449, GO:0046872=GO_REF:0000037, GO:0004169=GO_REF:0000003, GO:0016529=GO_REF:0000019, GO:0006493=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0030198=GO_REF:0000019, GO:0005789=PMID:14699049, GO:0016021=GO_REF:0000037} Q9Y6A1 Protein O-mannosyl-transferase 1 protein 20050308 {GO:0000030=TAS, GO:0001669=IEA, GO:0005783=TAS, GO:0005975=TAS, GO:0007275=TAS, GO:0046872=IEA, GO:0004169=IEA, GO:0016529=IEA, GO:0006493=IEA, GO:0016020=IEA, GO:0030198=IEA, GO:0005789=IDA, GO:0016021=IEA} carbohydrate metabolic process, extracellular matrix organization, multicellular organismal development, protein O-linked glycosylation acrosomal vesicle, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, membrane, sarcoplasmic reticulum dolichyl-phosphate-mannose-protein mannosyltransferase activity, mannosyltransferase activity, metal ion binding Human POMT2 UniProtKB UniProtKB {GO:0004169=GO_REF:0000003, GO:0000030=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0006493=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q9UKY4 Protein O-mannosyl-transferase 2 protein 20130413 {GO:0004169=IEA, GO:0000030=IEA, GO:0016020=IEA, GO:0006493=IEA, GO:0005789=IEA, GO:0016021=IEA, GO:0046872=IEA} protein O-linked glycosylation endoplasmic reticulum membrane, integral to membrane, membrane dolichyl-phosphate-mannose-protein mannosyltransferase activity, mannosyltransferase activity, metal ion binding Human UniProtKB-SubCell:SL-0097 POMZP3 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q6PJE2 POM121 and ZP3 fusion protein protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human PON1 BHF-UCL UniProtKB {GO:0019439=PMID:15772423, GO:0005509=PMID:15098021, GO:0034366=PMID:16682745, GO:0032411=PMID:15721011, GO:0051099=PMID:15721011, GO:0009636=GO_REF:0000019, GO:0005576=PMID:14718574, GO:0005615=PMID:7638166, GO:0046434=PMID:7638166, GO:0010875=PMID:15721011, GO:0042803=PMID:15772423, GO:0043231=GO_REF:0000019, GO:0009605=PMID:1657140, GO:0005543=PMID:10479665, GO:0004063=PMID:7638166, GO:0034364=PMID:15721011, GO:0034445=PMID:15342686, GO:0046470=PMID:15721011, GO:0004064=PMID:7638166, GO:0046395=PMID:7638166} P27169 Serum paraoxonase/arylesterase 1 protein 20090507 {GO:0019439=IDA, GO:0005509=IDA, GO:0034366=IDA, GO:0032411=IDA, GO:0051099=IDA, GO:0009636=IEA, GO:0005576=NAS, GO:0005615=IDA, GO:0046434=IDA, GO:0010875=IDA, GO:0042803=IDA, GO:0043231=IEA, GO:0009605=NAS, GO:0005543=IDA, GO:0004063=IDA, GO:0034364=IDA, GO:0034445=IDA, GO:0046470=IDA, GO:0004064=IDA, GO:0046395=IDA} aromatic compound catabolic process, carboxylic acid catabolic process, negative regulation of plasma lipoprotein particle oxidation, organophosphate catabolic process, phosphatidylcholine metabolic process, positive regulation of binding, positive regulation of cholesterol efflux, positive regulation of transporter activity, response to external stimulus, response to toxic substance extracellular region, extracellular space, high-density lipoprotein particle, intracellular membrane-bounded organelle, spherical high-density lipoprotein particle aryldialkylphosphatase activity, arylesterase activity, calcium ion binding, phospholipid binding, protein homodimerization activity Human PON2 BHF-UCL UniProtKB {GO:0005739=GO_REF:0000019, GO:0019439=PMID:15772423, GO:0005886=PMID:15772423, GO:0005634=GO_REF:0000019, GO:0005576=GO_REF:0000002, GO:0004064=GO_REF:0000003, GO:0006979=GO_REF:0000019, GO:0005764=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0042802=PMID:15772423} Q15165 Serum paraoxonase/arylesterase 2 protein 20090205 {GO:0005739=IEA, GO:0019439=IDA, GO:0005886=IDA, GO:0005634=IEA, GO:0005576=IEA, GO:0004064=IEA, GO:0006979=IEA, GO:0005764=IEA, GO:0046872=IEA, GO:0042802=IDA} aromatic compound catabolic process, response to oxidative stress extracellular region, lysosome, mitochondrion, nucleus, plasma membrane arylesterase activity, identical protein binding, metal ion binding Human PON3 BHF-UCL UniProtKB {GO:0047856=GO_REF:0000019, GO:0019439=PMID:15772423, GO:0005576=GO_REF:0000029, GO:0005615=GO_REF:0000039, GO:0046872=GO_REF:0000037, GO:0042803=PMID:15772423, GO:0043231=GO_REF:0000019, GO:0046226=GO_REF:0000019, GO:0009605=PMID:8661009, GO:0010124=GO_REF:0000019, GO:0004063=GO_REF:0000003, GO:0018733=GO_REF:0000019, GO:0004064=PMID:15772423, GO:0046395=PMID:15772423} Q15166 Serum paraoxonase/lactonase 3 protein 20090205 {GO:0047856=IEA, GO:0019439=IDA, GO:0005576=NAS, GO:0005615=IEA, GO:0046872=IEA, GO:0042803=IDA, GO:0043231=IEA, GO:0046226=IEA, GO:0009605=NAS, GO:0010124=IEA, GO:0004063=IEA, GO:0018733=IEA, GO:0004064=IDA, GO:0046395=IDA} aromatic compound catabolic process, carboxylic acid catabolic process, coumarin catabolic process, phenylacetate catabolic process, response to external stimulus extracellular region, extracellular space, intracellular membrane-bounded organelle 3,4-dihydrocoumarin hydrolase activity, aryldialkylphosphatase activity, arylesterase activity, dihydrocoumarin hydrolase activity, metal ion binding, protein homodimerization activity Human POP1 IntAct UniProtKB {GO:0005515=PMID:15096576, GO:0000171=PMID:8918471, GO:0000172=PMID:8918471, GO:0004526=PMID:8918471, GO:0005655=PMID:8918471, GO:0016078=PMID:8918471, GO:0001682=GO_REF:0000002} Q99575 Ribonucleases P/MRP protein subunit POP1 protein 20130415 {GO:0005515=IPI, GO:0000171=IDA, GO:0000172=IDA, GO:0004526=IDA, GO:0005655=IDA, GO:0016078=IDA, GO:0001682=IEA} tRNA 5'-leader removal, tRNA catabolic process nucleolar ribonuclease P complex, ribonuclease MRP complex protein binding, ribonuclease MRP activity, ribonuclease P activity Human UniProtKB:O95707 POP4 IntAct UniProtKB {GO:0005515=PMID:15096576, GO:0006379=GO_REF:0000002, GO:0000172=GO_REF:0000002, GO:0004526=GO_REF:0000003, GO:0006364=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0004540=GO_REF:0000002, GO:0005655=GO_REF:0000002, GO:0008033=GO_REF:0000037, GO:0030677=GO_REF:0000002} O95707 Ribonuclease P protein subunit p29 protein 20130415 {GO:0005515=IPI, GO:0006379=IEA, GO:0000172=IEA, GO:0004526=IEA, GO:0006364=IEA, GO:0003723=IEA, GO:0004540=IEA, GO:0005655=IEA, GO:0008033=IEA, GO:0030677=IEA} mRNA cleavage, rRNA processing, tRNA processing nucleolar ribonuclease P complex, ribonuclease MRP complex, ribonuclease P complex RNA binding, protein binding, ribonuclease P activity, ribonuclease activity Human UniProtKB:Q9BUL9 POP5 IntAct UniProtKB {GO:0005515=PMID:15096576, GO:0004526=GO_REF:0000003, GO:0005655=GO_REF:0000019, GO:0008033=GO_REF:0000019} Q969H6 Ribonuclease P/MRP protein subunit POP5 protein 20130415 {GO:0005515=IPI, GO:0004526=IEA, GO:0005655=IEA, GO:0008033=IEA} tRNA processing nucleolar ribonuclease P complex protein binding, ribonuclease P activity Human UniProtKB:O95707 POP7 IntAct UniProtKB {GO:0005515=PMID:15096576, GO:0004526=GO_REF:0000003, GO:0005634=PMID:9630247, GO:0005655=PMID:9630247, GO:0008033=GO_REF:0000037} O75817 Ribonuclease P protein subunit p20 protein 20130415 {GO:0005515=IPI, GO:0004526=IEA, GO:0005634=TAS, GO:0005655=TAS, GO:0008033=IEA} tRNA processing nucleolar ribonuclease P complex, nucleus protein binding, ribonuclease P activity Human UniProtKB:Q9BUL9 POPDC2 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0016020=GO_REF:0000002, GO:0016021=PMID:10882522} Q9HBU9 Popeye domain-containing protein 2 protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0016020=IEA, GO:0016021=NAS} biological_process integral to membrane, membrane molecular_function Human POR BHF-UCL UniProtKB {GO:0005515=PMID:21081644, GO:0050661=GO_REF:0000019, GO:0046210=GO_REF:0000019, GO:0043602=GO_REF:0000019, GO:0005783=GO_REF:0000029, GO:0060192=GO_REF:0000019, GO:0010181=GO_REF:0000019, GO:0050660=GO_REF:0000019, GO:0047726=GO_REF:0000019, GO:0070988=GO_REF:0000019, GO:0090346=PMID:19448135, GO:0005829=GO_REF:0000033, GO:0071372=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0045880=GO_REF:0000019, GO:0071375=GO_REF:0000019, GO:0090031=GO_REF:0000019, GO:0032332=GO_REF:0000019, GO:0003420=GO_REF:0000019, GO:0043154=GO_REF:0000019, GO:0009437=GO_REF:0000019, GO:0019395=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0005506=GO_REF:0000002, GO:0004128=GO_REF:0000019, GO:0007584=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0009055=GO_REF:0000019, GO:0018393=GO_REF:0000019, GO:0009812=GO_REF:0000019, GO:0003958=PMID:19448135, GO:0016787=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0016709=GO_REF:0000033, GO:0005789=GO_REF:0000039, GO:0016491=GO_REF:0000033, GO:0032770=PMID:19448135, GO:0019899=GO_REF:0000019, GO:0045542=GO_REF:0000019, GO:0055114=PMID:19448135} P16435 NADPH--cytochrome P450 reductase protein 20110110 {GO:0005515=IPI, GO:0050661=IEA, GO:0046210=IEA, GO:0043602=IEA, GO:0005783=TAS, GO:0060192=IEA, GO:0010181=IEA, GO:0050660=IEA, GO:0047726=IEA, GO:0070988=IEA, GO:0090346=IDA, GO:0005829=IBA, GO:0071372=IEA, GO:0005739=IEA, GO:0045880=IEA, GO:0071375=IEA, GO:0090031=IEA, GO:0032332=IEA, GO:0003420=IEA, GO:0043154=IEA, GO:0009437=IEA, GO:0019395=IEA, GO:0043066=IEA, GO:0005506=IEA, GO:0004128=IEA, GO:0007584=IEA, GO:0042493=IEA, GO:0009055=IEA, GO:0018393=IEA, GO:0009812=IEA, GO:0003958=IDA, GO:0016787=IEA, GO:0016020=IEA, GO:0016709=IBA, GO:0005789=IEA, GO:0016491=IBA, GO:0032770=IDA, GO:0019899=IEA, GO:0045542=IEA, GO:0055114=IDA} carnitine metabolic process, cellular organofluorine metabolic process, cellular response to follicle-stimulating hormone stimulus, cellular response to peptide hormone stimulus, demethylation, fatty acid oxidation, flavonoid metabolic process, internal peptidyl-lysine acetylation, negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of lipase activity, nitrate catabolic process, nitric oxide catabolic process, oxidation-reduction process, positive regulation of cholesterol biosynthetic process, positive regulation of chondrocyte differentiation, positive regulation of monooxygenase activity, positive regulation of smoothened signaling pathway, positive regulation of steroid hormone biosynthetic process, regulation of growth plate cartilage chondrocyte proliferation, response to drug, response to nutrient cytosol, endoplasmic reticulum, endoplasmic reticulum membrane, membrane, mitochondrion FMN binding, NADP binding, NADPH-hemoprotein reductase activity, cytochrome-b5 reductase activity, acting on NAD(P)H, electron carrier activity, enzyme binding, flavin adenine dinucleotide binding, hydrolase activity, iron ion binding, iron-cytochrome-c reductase activity, oxidoreductase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen, protein binding Human PORCN ENSEMBL UniProtKB {GO:0009100=GO_REF:0000019, GO:0016746=GO_REF:0000037, GO:0030176=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0016055=GO_REF:0000037, GO:0016740=GO_REF:0000038} Q9H237 Protein-cysteine N-palmitoyltransferase porcupine protein 20130413 {GO:0009100=IEA, GO:0016746=IEA, GO:0030176=IEA, GO:0016021=IEA, GO:0016055=IEA, GO:0016740=IEA} Wnt receptor signaling pathway, glycoprotein metabolic process integral to endoplasmic reticulum membrane, integral to membrane transferase activity, transferase activity, transferring acyl groups Human Ensembl:ENSMUSP00000076790 POT1 BHF-UCL UniProtKB {GO:0051974=PMID:15632080, GO:0005515=PMID:15657433, GO:0000781=PMID:12768206, GO:0016233=PMID:15657433, GO:0010521=PMID:15632080, GO:0003677=GO_REF:0000002, GO:0051973=PMID:17237768, GO:0060383=PMID:16043710, GO:0032212=PMID:12768206, GO:0032211=PMID:15181449, GO:0000723=Reactome:REACT_7970, GO:0051096=PMID:16030011, GO:0032203=PMID:16043710, GO:0017151=PMID:16030011, GO:0005654=Reactome:REACT_8031, GO:0032508=PMID:16030011, GO:0043047=PMID:15632080, GO:0007004=PMID:12768206, GO:0000784=GO_REF:0000002, GO:0000783=PMID:16880378} Q9NUX5 Protection of telomeres protein 1 protein 20081208 {GO:0051974=IDA, GO:0005515=IPI, GO:0000781=IDA, GO:0016233=IMP, GO:0010521=IDA, GO:0003677=IEA, GO:0051973=IDA, GO:0060383=IDA, GO:0032212=IMP, GO:0032211=IMP, GO:0000723=TAS, GO:0051096=IDA, GO:0032203=IDA, GO:0017151=IPI, GO:0005654=TAS, GO:0032508=IDA, GO:0043047=IDA, GO:0007004=IDA, GO:0000784=IEA, GO:0000783=IDA} DNA duplex unwinding, negative regulation of telomerase activity, negative regulation of telomere maintenance via telomerase, positive regulation of DNA strand elongation, positive regulation of helicase activity, positive regulation of telomerase activity, positive regulation of telomere maintenance via telomerase, telomere capping, telomere formation via telomerase, telomere maintenance, telomere maintenance via telomerase chromosome, telomeric region, nuclear chromosome, telomeric region, nuclear telomere cap complex, nucleoplasm DEAD/H-box RNA helicase binding, DNA binding, protein binding, single-stranded telomeric DNA binding, telomerase inhibitor activity Human POTEB null null {} null null null null {} null null null POTEC null null {} null null null null {} null null null POTED UniProtKB UniProtKB {GO:0005886=GO_REF:0000039} Q86YR6 POTE ankyrin domain family member D protein 20130413 {GO:0005886=IEA} plasma membrane Human UniProtKB-SubCell:SL-0039 POTEE InterPro UniProtKB {GO:0005524=GO_REF:0000002} Q6S8J3 POTE ankyrin domain family member E protein 20130413 {GO:0005524=IEA} ATP binding Human InterPro:IPR004001 POTEF UniProtKB UniProtKB {GO:0005938=GO_REF:0000039, GO:0005524=GO_REF:0000002} A5A3E0 POTE ankyrin domain family member F protein 20130413 {GO:0005938=IEA, GO:0005524=IEA} cell cortex ATP binding Human UniProtKB-SubCell:SL-0138 POTEG null null {} null null null null {} null null null POTEH null null {} null null null null {} null null null POTEI InterPro UniProtKB {GO:0005524=GO_REF:0000002} P0CG38 POTE ankyrin domain family member I protein 20130413 {GO:0005524=IEA} ATP binding Human InterPro:IPR004001 POTEJ InterPro UniProtKB {GO:0005524=GO_REF:0000002} P0CG39 POTE ankyrin domain family member J protein 20130413 {GO:0005524=IEA} ATP binding Human InterPro:IPR004001 POTEM null null {} null null null null {} null null null POU1F1 HPA UniProtKB {GO:0001102=PMID:12612071, GO:0001105=PMID:9685346, GO:0008284=GO_REF:0000019, GO:0008285=PMID:9392392, GO:0003700=PMID:9482665, GO:0006366=PMID:1487156, GO:0001708=GO_REF:0000019, GO:0060133=GO_REF:0000019, GO:0003714=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000122=GO_REF:0000019, GO:0008340=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0001077=GO_REF:0000019, GO:0045944=PMID:9685346, GO:0043567=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0030183=GO_REF:0000019, GO:0032962=GO_REF:0000019, GO:0040018=GO_REF:0000019, GO:0045893=PMID:9482665, GO:0051169=GO_REF:0000019} P28069 Pituitary-specific positive transcription factor 1 protein 20111111 {GO:0001102=IPI, GO:0001105=IDA, GO:0008284=IEA, GO:0008285=TAS, GO:0003700=IDA, GO:0006366=TAS, GO:0001708=IEA, GO:0060133=IEA, GO:0003714=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0000122=IEA, GO:0008340=IEA, GO:0043565=IEA, GO:0005737=IDA, GO:0001077=IEA, GO:0045944=IDA, GO:0043567=IEA, GO:0003682=IEA, GO:0030183=IEA, GO:0032962=IEA, GO:0040018=IEA, GO:0045893=IDA, GO:0051169=IEA} B cell differentiation, cell fate specification, determination of adult lifespan, negative regulation of cell proliferation, negative regulation of transcription from RNA polymerase II promoter, nuclear transport, positive regulation of cell proliferation, positive regulation of inositol trisphosphate biosynthetic process, positive regulation of multicellular organism growth, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of insulin-like growth factor receptor signaling pathway, somatotropin secreting cell development, transcription from RNA polymerase II promoter cytoplasm, nucleolus, nucleus RNA polymerase II activating transcription factor binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II transcription coactivator activity, chromatin binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human POU2AF1 PINC UniProtKB {GO:0003712=PMID:7859290, GO:0006355=GO_REF:0000037, GO:0006366=PMID:7859290, GO:0006959=PMID:7859290, GO:0003713=PMID:7859290, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000019} Q16633 POU domain class 2-associating factor 1 protein 20030904 {GO:0003712=TAS, GO:0006355=IEA, GO:0006366=TAS, GO:0006959=TAS, GO:0003713=TAS, GO:0005634=IEA, GO:0003677=IEA} humoral immune response, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter nucleus DNA binding, transcription coactivator activity, transcription cofactor activity Human POU2F1 IntAct UniProtKB {GO:0005515=PMID:10976766, GO:0043565=PMID:9242494, GO:0010467=Reactome:REACT_71, GO:0030910=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0001077=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0060235=GO_REF:0000019, GO:0005654=Reactome:REACT_1607, GO:0005634=PMID:11891224, GO:0006383=Reactome:REACT_1371, GO:0045892=PMID:11891224} P14859 POU domain, class 2, transcription factor 1 protein 20130415 {GO:0005515=IPI, GO:0043565=IDA, GO:0010467=TAS, GO:0030910=IEA, GO:0005667=IEA, GO:0001077=IEA, GO:0003700=IEA, GO:0060235=IEA, GO:0005654=TAS, GO:0005634=IDA, GO:0006383=TAS, GO:0045892=IDA} gene expression, lens induction in camera-type eye, negative regulation of transcription, DNA-dependent, olfactory placode formation, transcription from RNA polymerase III promoter nucleoplasm, nucleus, transcription factor complex RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:P08047 POU2F2 MGI UniProtKB {GO:0043565=PMID:9242494, GO:0005737=GO_REF:0000039, GO:0003700=GO_REF:0000019, GO:0006366=PMID:9442393, GO:0006959=PMID:9442393, GO:0019904=GO_REF:0000019, GO:0002335=GO_REF:0000019, GO:0002380=GO_REF:0000019, GO:0048469=GO_REF:0000019, GO:0005634=PMID:9242494, GO:0045893=GO_REF:0000019, GO:0003677=GO_REF:0000038} P09086 POU domain, class 2, transcription factor 2 protein 20080302 {GO:0043565=IDA, GO:0005737=IEA, GO:0003700=IEA, GO:0006366=TAS, GO:0006959=TAS, GO:0019904=IEA, GO:0002335=IEA, GO:0002380=IEA, GO:0048469=IEA, GO:0005634=IDA, GO:0045893=IEA, GO:0003677=IEA} cell maturation, humoral immune response, immunoglobulin secretion involved in immune response, mature B cell differentiation, positive regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter cytoplasm, nucleus DNA binding, protein domain specific binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human POU2F3 HPA UniProtKB {GO:0005515=PMID:12624109, GO:0005667=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0006357=PMID:10473598, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000038, GO:0006351=GO_REF:0000037, GO:0043922=PMID:14645924, GO:0043565=PMID:9242494, GO:0005737=GO_REF:0000052, GO:0008544=PMID:10473598, GO:0030216=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0042060=GO_REF:0000019, GO:0046983=GO_REF:0000019} Q9UKI9 POU domain, class 2, transcription factor 3 protein 20100326 {GO:0005515=IPI, GO:0005667=IEA, GO:0003700=IEA, GO:0006357=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA, GO:0043922=IDA, GO:0043565=IDA, GO:0005737=IDA, GO:0008544=TAS, GO:0030216=IEA, GO:0045944=IEA, GO:0042060=IEA, GO:0046983=IEA} epidermis development, keratinocyte differentiation, negative regulation by host of viral transcription, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent, wound healing cytoplasm, nucleolus, nucleus, transcription factor complex DNA binding, protein binding, protein dimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human POU3F1 MGI UniProtKB {GO:0043565=PMID:9242494, GO:0010628=GO_REF:0000024, GO:0005667=GO_REF:0000019, GO:0001105=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0030216=GO_REF:0000019, GO:0022011=GO_REF:0000019, GO:0005634=GO_REF:0000024, GO:0030900=GO_REF:0000019, GO:0008366=PMID:8662541, GO:0045893=GO_REF:0000024} Q03052 POU domain, class 3, transcription factor 1 protein 20080302 {GO:0043565=IDA, GO:0010628=ISS, GO:0005667=IEA, GO:0001105=IEA, GO:0003700=IEA, GO:0030216=IEA, GO:0022011=IEA, GO:0005634=ISS, GO:0030900=IEA, GO:0008366=TAS, GO:0045893=ISS} axon ensheathment, forebrain development, keratinocyte differentiation, myelination in peripheral nervous system, positive regulation of gene expression, positive regulation of transcription, DNA-dependent nucleus, transcription factor complex RNA polymerase II transcription coactivator activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human POU3F2 IntAct UniProtKB {GO:0005515=PMID:11029584, GO:0005667=GO_REF:0000019, GO:0021985=GO_REF:0000019, GO:0008284=PMID:15024079, GO:0001105=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0071310=GO_REF:0000019, GO:0021869=GO_REF:0000019, GO:0022011=GO_REF:0000019, GO:0021979=GO_REF:0000019, GO:0042802=PMID:11029584, GO:0043565=GO_REF:0000019, GO:0008544=GO_REF:0000019, GO:0014002=GO_REF:0000019, GO:0030182=GO_REF:0000019, GO:0021799=GO_REF:0000019, GO:0040018=GO_REF:0000019, GO:0050770=GO_REF:0000019} P20265 POU domain, class 3, transcription factor 2 protein 20130415 {GO:0005515=IPI, GO:0005667=IEA, GO:0021985=IEA, GO:0008284=IDA, GO:0001105=IEA, GO:0003700=IEA, GO:0071310=IEA, GO:0021869=IEA, GO:0022011=IEA, GO:0021979=IEA, GO:0042802=IPI, GO:0043565=IEA, GO:0008544=IEA, GO:0014002=IEA, GO:0030182=IEA, GO:0021799=IEA, GO:0040018=IEA, GO:0050770=IEA} astrocyte development, cellular response to organic substance, cerebral cortex radially oriented cell migration, epidermis development, forebrain ventricular zone progenitor cell division, hypothalamus cell differentiation, myelination in peripheral nervous system, neurohypophysis development, neuron differentiation, positive regulation of cell proliferation, positive regulation of multicellular organism growth, regulation of axonogenesis transcription factor complex RNA polymerase II transcription coactivator activity, identical protein binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:P20265 POU3F3 PINC UniProtKB {GO:0072227=GO_REF:0000024, GO:0043066=GO_REF:0000024, GO:0008284=GO_REF:0000024, GO:0003700=GO_REF:0000002, GO:0072236=GO_REF:0000024, GO:0072218=GO_REF:0000024, GO:0021869=GO_REF:0000019, GO:0072233=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0007417=PMID:8703082, GO:0006351=GO_REF:0000037, GO:0072240=GO_REF:0000024, GO:0043565=GO_REF:0000024, GO:0010628=GO_REF:0000024, GO:0045944=GO_REF:0000019, GO:0021799=GO_REF:0000019, GO:0071837=GO_REF:0000019, GO:0045893=GO_REF:0000024, GO:0045892=GO_REF:0000024} P20264 POU domain, class 3, transcription factor 3 protein 20030904 {GO:0072227=ISS, GO:0043066=ISS, GO:0008284=ISS, GO:0003700=IEA, GO:0072236=ISS, GO:0072218=ISS, GO:0021869=IEA, GO:0072233=ISS, GO:0005634=ISS, GO:0007417=TAS, GO:0006351=IEA, GO:0072240=ISS, GO:0043565=ISS, GO:0010628=ISS, GO:0045944=IEA, GO:0021799=IEA, GO:0071837=IEA, GO:0045893=ISS, GO:0045892=ISS} central nervous system development, cerebral cortex radially oriented cell migration, forebrain ventricular zone progenitor cell division, metanephric DCT cell differentiation, metanephric ascending thin limb development, metanephric loop of Henle development, metanephric macula densa development, metanephric thick ascending limb development, negative regulation of apoptotic process, negative regulation of transcription, DNA-dependent, positive regulation of cell proliferation, positive regulation of gene expression, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus HMG box domain binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human POU3F4 UniProtKB UniProtKB {GO:0003700=GO_REF:0000019, GO:0003690=GO_REF:0000019, GO:0006366=GO_REF:0000019, GO:0003680=GO_REF:0000019, GO:0007605=GO_REF:0000019, GO:0021879=GO_REF:0000019, GO:0090103=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:2001054=GO_REF:0000024} P49335 POU domain, class 3, transcription factor 4 protein 20111004 {GO:0003700=IEA, GO:0003690=IEA, GO:0006366=IEA, GO:0003680=IEA, GO:0007605=IEA, GO:0021879=IEA, GO:0090103=ISS, GO:0005634=IEA, GO:2001054=ISS} cochlea morphogenesis, forebrain neuron differentiation, negative regulation of mesenchymal cell apoptotic process, sensory perception of sound, transcription from RNA polymerase II promoter nucleus AT DNA binding, double-stranded DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:P62515 POU4F1 BHF-UCL UniProtKB {GO:0043005=GO_REF:0000019, GO:0000790=GO_REF:0000019, GO:0021986=GO_REF:0000019, GO:0021535=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0051355=GO_REF:0000019, GO:0003705=GO_REF:0000024, GO:0021559=GO_REF:0000024, GO:0048665=GO_REF:0000024, GO:0021953=GO_REF:0000019, GO:0007409=PMID:17239249, GO:0000122=GO_REF:0000024, GO:0007416=PMID:8995448, GO:0060384=PMID:17239249, GO:0043524=PMID:17239249, GO:0001077=GO_REF:0000019, GO:0001967=GO_REF:0000019, GO:0050767=GO_REF:0000019, GO:0003223=GO_REF:0000019, GO:0045944=GO_REF:0000024, GO:0048880=GO_REF:0000024, GO:0048935=GO_REF:0000024, GO:0000980=GO_REF:0000024, GO:0007498=GO_REF:0000019} Q01851 POU domain, class 4, transcription factor 1 protein 20110708 {GO:0043005=IEA, GO:0000790=IEA, GO:0021986=IEA, GO:0021535=IEA, GO:0043065=IEA, GO:0051355=IEA, GO:0003705=ISS, GO:0021559=ISS, GO:0048665=ISS, GO:0021953=IEA, GO:0007409=TAS, GO:0000122=ISS, GO:0007416=TAS, GO:0060384=TAS, GO:0043524=TAS, GO:0001077=IEA, GO:0001967=IEA, GO:0050767=IEA, GO:0003223=IEA, GO:0045944=ISS, GO:0048880=ISS, GO:0048935=ISS, GO:0000980=ISS, GO:0007498=IEA} axonogenesis, cell migration in hindbrain, central nervous system neuron differentiation, habenula development, innervation, mesoderm development, negative regulation of neuron apoptotic process, negative regulation of transcription from RNA polymerase II promoter, neuron fate specification, peripheral nervous system neuron development, positive regulation of apoptotic process, positive regulation of transcription from RNA polymerase II promoter, proprioception involved in equilibrioception, regulation of neurogenesis, sensory system development, suckling behavior, synapse assembly, trigeminal nerve development, ventricular compact myocardium morphogenesis neuron projection, nuclear chromatin RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II distal enhancer sequence-specific DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity Human UniProtKB:P17208 POU4F2 UniProtKB UniProtKB {GO:0031290=GO_REF:0000019, GO:0060041=GO_REF:0000024, GO:0007605=GO_REF:0000019, GO:0045597=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0000122=GO_REF:0000024, GO:0000978=PMID:21241485, GO:0001078=GO_REF:0000024, GO:0001077=PMID:21241485, GO:0016607=GO_REF:0000039, GO:0000165=PMID:21241485, GO:0007411=GO_REF:0000024, GO:0003682=GO_REF:0000019, GO:0045944=PMID:21241485, GO:0030182=GO_REF:0000024, GO:0050885=GO_REF:0000019, GO:0030520=PMID:21241485} Q12837 POU domain, class 4, transcription factor 2 protein 20110722 {GO:0031290=IEA, GO:0060041=ISS, GO:0007605=IEA, GO:0045597=ISS, GO:0005634=ISS, GO:0000122=ISS, GO:0000978=IDA, GO:0001078=ISS, GO:0001077=IDA, GO:0016607=IEA, GO:0000165=IDA, GO:0007411=ISS, GO:0003682=IEA, GO:0045944=IDA, GO:0030182=ISS, GO:0050885=IEA, GO:0030520=IDA} MAPK cascade, axon guidance, intracellular estrogen receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, neuromuscular process controlling balance, neuron differentiation, positive regulation of cell differentiation, positive regulation of transcription from RNA polymerase II promoter, retina development in camera-type eye, retinal ganglion cell axon guidance, sensory perception of sound nuclear speck, nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, chromatin binding Human UniProtKB:Q63934 POU5F1 BHF-UCL UniProtKB {GO:0005515=PMID:15523054, GO:0010468=PMID:18388306, GO:0006355=PMID:16153702, GO:0003700=PMID:16153702, GO:0006366=GO_REF:0000024, GO:0009786=GO_REF:0000024, GO:0000981=GO_REF:0000024, GO:0001824=GO_REF:0000024, GO:0009611=PMID:17982423, GO:0005634=PMID:19274063, GO:0003677=PMID:16153702, GO:0009653=PMID:9814708, GO:0001714=PMID:20713518, GO:0005829=PMID:18000303, GO:0043565=PMID:20713518, GO:0005737=PMID:20458727, GO:0035198=PMID:18710938, GO:0045944=PMID:20713518, GO:0060965=PMID:19409607, GO:0042789=GO_REF:0000024, GO:0005654=PMID:20458727, GO:0035019=PMID:19409607, GO:0031625=PMID:19274063} Q01860 POU domain, class 5, transcription factor 1 protein 20101229 {GO:0005515=IPI, GO:0010468=IMP, GO:0006355=IDA, GO:0003700=IDA, GO:0006366=ISS, GO:0009786=ISS, GO:0000981=ISS, GO:0001824=ISS, GO:0009611=IEP, GO:0005634=IDA, GO:0003677=IDA, GO:0009653=TAS, GO:0001714=IDA, GO:0005829=IDA, GO:0043565=IDA, GO:0005737=IDA, GO:0035198=IDA, GO:0045944=IDA, GO:0060965=IMP, GO:0042789=ISS, GO:0005654=IDA, GO:0035019=IDA, GO:0031625=IPI} anatomical structure morphogenesis, blastocyst development, endodermal cell fate specification, mRNA transcription from RNA polymerase II promoter, negative regulation of gene silencing by miRNA, positive regulation of transcription from RNA polymerase II promoter, regulation of asymmetric cell division, regulation of gene expression, regulation of transcription, DNA-dependent, response to wounding, somatic stem cell maintenance, transcription from RNA polymerase II promoter cytoplasm, cytosol, nucleoplasm, nucleus DNA binding, miRNA binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity, ubiquitin protein ligase binding Human UniProtKB:P20263 PP2D1 InterPro UniProtKB {GO:0003824=GO_REF:0000002} A8MPX8 Protein phosphatase 2C-like domain-containing protein 1 protein 20130413 {GO:0003824=IEA} catalytic activity Human InterPro:IPR001932 PPA1 InterPro UniProtKB {GO:0010467=Reactome:REACT_71, GO:0005737=GO_REF:0000002, GO:0000287=GO_REF:0000002, GO:0004427=GO_REF:0000002, GO:0071344=Reactome:REACT_21259, GO:0006796=GO_REF:0000002, GO:0006418=Reactome:REACT_15482, GO:0005829=Reactome:REACT_206} Q5SQT6 Inorganic pyrophosphatase protein 20130413 {GO:0010467=TAS, GO:0005737=IEA, GO:0000287=IEA, GO:0004427=IEA, GO:0071344=TAS, GO:0006796=IEA, GO:0006418=TAS, GO:0005829=TAS} diphosphate metabolic process, gene expression, phosphate-containing compound metabolic process, tRNA aminoacylation for protein translation cytoplasm, cytosol inorganic diphosphatase activity, magnesium ion binding Human InterPro:IPR008162 PPA2 Reactome UniProtKB {GO:0005739=GO_REF:0000019, GO:0010467=Reactome:REACT_71, GO:0005737=GO_REF:0000002, GO:0000287=GO_REF:0000002, GO:0005759=Reactome:REACT_21277, GO:0004427=Reactome:REACT_21277, GO:0071344=Reactome:REACT_21259, GO:0006796=GO_REF:0000002, GO:0006418=Reactome:REACT_15482} Q9H2U2 Inorganic pyrophosphatase 2, mitochondrial protein 20130213 {GO:0005739=IEA, GO:0010467=TAS, GO:0005737=IEA, GO:0000287=IEA, GO:0005759=TAS, GO:0004427=TAS, GO:0071344=TAS, GO:0006796=IEA, GO:0006418=TAS} diphosphate metabolic process, gene expression, phosphate-containing compound metabolic process, tRNA aminoacylation for protein translation cytoplasm, mitochondrial matrix, mitochondrion inorganic diphosphatase activity, magnesium ion binding Human PPAN HPA UniProtKB {GO:0008380=PMID:10944437, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9NQ55 Suppressor of SWI4 1 homolog protein 20110516 {GO:0008380=TAS, GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA} RNA splicing cytoplasm, nucleolus, nucleus Human PPAP2A Reactome UniProtKB {GO:0006629=PMID:9705349, GO:0006665=Reactome:REACT_19323, GO:0008354=PMID:9305923, GO:0008285=PMID:9468526, GO:0005886=Reactome:REACT_19309, GO:0030148=Reactome:REACT_115810, GO:0044281=Reactome:REACT_111217, GO:0008195=PMID:9468526, GO:0007205=PMID:9468526, GO:0019216=PMID:9468526, GO:0016020=PMID:9468526, GO:0030518=PMID:9468526, GO:0046839=PMID:9468526, GO:0005887=PMID:9705349, GO:0030521=PMID:9468526} O14494 Lipid phosphate phosphohydrolase 1 protein 20130301 {GO:0006629=NAS, GO:0006665=TAS, GO:0008354=TAS, GO:0008285=NAS, GO:0005886=TAS, GO:0030148=TAS, GO:0044281=TAS, GO:0008195=IDA, GO:0007205=TAS, GO:0019216=NAS, GO:0016020=IDA, GO:0030518=TAS, GO:0046839=TAS, GO:0005887=NAS, GO:0030521=NAS} androgen receptor signaling pathway, germ cell migration, intracellular steroid hormone receptor signaling pathway, lipid metabolic process, negative regulation of cell proliferation, phospholipid dephosphorylation, protein kinase C-activating G-protein coupled receptor signaling pathway, regulation of lipid metabolic process, small molecule metabolic process, sphingolipid biosynthetic process, sphingolipid metabolic process integral to plasma membrane, membrane, plasma membrane phosphatidate phosphatase activity Human PPAP2B BHF-UCL UniProtKB {GO:0005515=PMID:20123964, GO:0006629=PMID:9705349, GO:0030111=GO_REF:0000019, GO:0005886=Reactome:REACT_19185, GO:0050731=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0042577=GO_REF:0000019, GO:0051091=PMID:20123964, GO:0005912=PMID:20123964, GO:0004721=PMID:9705349, GO:0006665=Reactome:REACT_19323, GO:0008354=PMID:9305923, GO:0005794=GO_REF:0000039, GO:0001568=GO_REF:0000019, GO:0044329=PMID:20123964, GO:0030148=Reactome:REACT_115810, GO:0050821=PMID:20123964, GO:0008195=GO_REF:0000003, GO:0044328=PMID:20123964, GO:0001702=GO_REF:0000019, GO:0034109=PMID:20123964, GO:0005178=GO_REF:0000019, GO:0016020=PMID:9305923, GO:0044330=PMID:20123964, GO:0001933=PMID:20123964, GO:0016021=GO_REF:0000037, GO:0006644=GO_REF:0000019} O14495 Lipid phosphate phosphohydrolase 3 protein 20100721 {GO:0005515=IPI, GO:0006629=NAS, GO:0030111=IEA, GO:0005886=TAS, GO:0050731=IEA, GO:0044281=TAS, GO:0042577=IEA, GO:0051091=IDA, GO:0005912=TAS, GO:0004721=TAS, GO:0006665=TAS, GO:0008354=TAS, GO:0005794=IEA, GO:0001568=IEA, GO:0044329=IMP, GO:0030148=TAS, GO:0050821=IDA, GO:0008195=IEA, GO:0044328=IMP, GO:0001702=IEA, GO:0034109=IDA, GO:0005178=IEA, GO:0016020=TAS, GO:0044330=IMP, GO:0001933=IDA, GO:0016021=IEA, GO:0006644=IEA} blood vessel development, canonical Wnt receptor signaling pathway involved in positive regulation of cell-cell adhesion, canonical Wnt receptor signaling pathway involved in positive regulation of endothelial cell migration, canonical Wnt receptor signaling pathway involved in positive regulation of wound healing, gastrulation with mouth forming second, germ cell migration, homotypic cell-cell adhesion, lipid metabolic process, negative regulation of protein phosphorylation, phospholipid metabolic process, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of sequence-specific DNA binding transcription factor activity, protein stabilization, regulation of Wnt receptor signaling pathway, small molecule metabolic process, sphingolipid biosynthetic process, sphingolipid metabolic process Golgi apparatus, adherens junction, integral to membrane, membrane, plasma membrane integrin binding, lipid phosphatase activity, phosphatidate phosphatase activity, phosphoprotein phosphatase activity, protein binding Human UniProtKB:O60716 PPAP2C Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0005886=Reactome:REACT_19185, GO:0016020=PMID:9607309, GO:0030148=Reactome:REACT_115810, GO:0004721=PMID:9607309, GO:0044281=Reactome:REACT_111217, GO:0008195=GO_REF:0000003, GO:0016021=GO_REF:0000037, GO:0003824=GO_REF:0000002} O43688 Lipid phosphate phosphohydrolase 2 protein 20130301 {GO:0006665=TAS, GO:0005886=TAS, GO:0016020=TAS, GO:0030148=TAS, GO:0004721=TAS, GO:0044281=TAS, GO:0008195=IEA, GO:0016021=IEA, GO:0003824=IEA} small molecule metabolic process, sphingolipid biosynthetic process, sphingolipid metabolic process integral to membrane, membrane, plasma membrane catalytic activity, phosphatidate phosphatase activity, phosphoprotein phosphatase activity Human PPAPDC2 UniProtKB UniProtKB {GO:0016787=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q8IY26 Presqualene diphosphate phosphatase protein 20130413 {GO:0016787=IEA, GO:0016021=IEA} integral to membrane hydrolase activity Human UniProtKB-KW:KW-0378 PPARA GOC UniProtKB {GO:0005515=PMID:16554032, GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_15525, GO:0003700=PMID:19955185, GO:0003707=PMID:19955185, GO:0032403=GO_REF:0000019, GO:0007507=GO_REF:0000019, GO:0004879=PMID:19955185, GO:0045820=PMID:19955185, GO:0044255=Reactome:REACT_22279, GO:0031624=PMID:19955185, GO:0001103=PMID:19955185, GO:0032868=GO_REF:0000019, GO:0010745=PMID:12700342, GO:0019902=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0046321=GO_REF:0000024, GO:1901215=GO_REF:0000019, GO:0000122=PMID:12700342, GO:0008544=GO_REF:0000019, GO:0042060=GO_REF:0000019, GO:0042157=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_19370, GO:0015908=PMID:16271724, GO:0045893=PMID:12955147, GO:0032091=GO_REF:0000019, GO:0006629=PMID:9792666, GO:0051525=GO_REF:0000019, GO:0032099=GO_REF:0000024, GO:0005634=PMID:16271724, GO:0010871=PMID:12700342, GO:0045776=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:2000678=GO_REF:0000019, GO:0008289=PMID:12955147, GO:0072366=PMID:19955185, GO:0097371=GO_REF:0000019, GO:0072363=PMID:19955185, GO:0045944=PMID:19955185, GO:0008144=PMID:9113987, GO:0006631=GO_REF:0000019, GO:0072369=PMID:19955185, GO:0001666=GO_REF:0000019, GO:0070166=GO_REF:0000019, GO:0003677=PMID:10860941, GO:0010887=PMID:19114110, GO:0043565=GO_REF:0000024, GO:0035095=GO_REF:0000019, GO:0010891=PMID:12700342, GO:0032000=PMID:16271724, GO:0030522=PMID:19955185} Q07869 Peroxisome proliferator-activated receptor alpha protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0006367=TAS, GO:0003700=IDA, GO:0003707=IDA, GO:0032403=IEA, GO:0007507=IEA, GO:0004879=IDA, GO:0045820=IC, GO:0044255=TAS, GO:0031624=IPI, GO:0001103=IPI, GO:0032868=IEA, GO:0010745=IC, GO:0019902=IEA, GO:0019904=IEA, GO:0046321=ISS, GO:1901215=IEA, GO:0000122=IDA, GO:0008544=IEA, GO:0042060=IEA, GO:0042157=IEA, GO:0008270=IEA, GO:0005654=TAS, GO:0015908=TAS, GO:0045893=IDA, GO:0032091=IEA, GO:0006629=TAS, GO:0051525=IEA, GO:0032099=ISS, GO:0005634=TAS, GO:0010871=IDA, GO:0045776=IEA, GO:0044281=TAS, GO:2000678=IEA, GO:0008289=IDA, GO:0072366=IDA, GO:0097371=IEA, GO:0072363=IDA, GO:0045944=IDA, GO:0008144=IDA, GO:0006631=IEA, GO:0072369=IDA, GO:0001666=IEA, GO:0070166=IEA, GO:0003677=TAS, GO:0010887=IDA, GO:0043565=ISS, GO:0035095=IEA, GO:0010891=IDA, GO:0032000=TAS, GO:0030522=IDA} behavioral response to nicotine, cellular lipid metabolic process, enamel mineralization, epidermis development, fatty acid metabolic process, fatty acid transport, gene expression, heart development, intracellular receptor signaling pathway, lipid metabolic process, lipoprotein metabolic process, negative regulation of appetite, negative regulation of blood pressure, negative regulation of cholesterol storage, negative regulation of glycolysis, negative regulation of macrophage derived foam cell differentiation, negative regulation of neuron death, negative regulation of protein binding, negative regulation of receptor biosynthetic process, negative regulation of sequestering of triglyceride, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription regulatory region DNA binding, positive regulation of fatty acid beta-oxidation, positive regulation of fatty acid oxidation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter, regulation of glycolysis by positive regulation of transcription from RNA polymerase II promoter, regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter, response to hypoxia, response to insulin stimulus, small molecule metabolic process, transcription initiation from RNA polymerase II promoter, wound healing nucleoplasm, nucleus DNA binding, MDM2/MDM4 family protein binding, NFAT protein binding, RNA polymerase II repressing transcription factor binding, drug binding, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, lipid binding, phosphatase binding, protein binding, protein complex binding, protein domain specific binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity, ubiquitin conjugating enzyme binding, zinc ion binding Human PPARD GOC UniProtKB {GO:0006629=GO_REF:0000024, GO:0010467=Reactome:REACT_71, GO:0051546=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0006367=Reactome:REACT_15525, GO:0003700=PMID:12955147, GO:0008283=GO_REF:0000024, GO:0042640=GO_REF:0000019, GO:0045598=GO_REF:0000019, GO:0070539=PMID:10198642, GO:0003707=GO_REF:0000002, GO:0050680=GO_REF:0000019, GO:0005634=PMID:11551955, GO:0006091=PMID:1333051, GO:0008366=GO_REF:0000024, GO:0030154=GO_REF:0000019, GO:0008289=PMID:12955147, GO:0009062=PMID:15192438, GO:0046697=PMID:11551955, GO:0015758=PMID:15793256, GO:0008144=PMID:9113987, GO:0006006=PMID:15793256, GO:0004879=PMID:12955147, GO:0008203=PMID:15192438, GO:0005504=GO_REF:0000029, GO:0006635=PMID:15803109, GO:0006357=PMID:1333051, GO:0007566=PMID:11551955, GO:0031589=GO_REF:0000019, GO:0006915=PMID:11551955, GO:0014068=GO_REF:0000019, GO:0001890=GO_REF:0000019, GO:0000122=GO_REF:0000024, GO:0003677=GO_REF:0000024, GO:0043616=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0042060=GO_REF:0000019, GO:0045600=PMID:10991946, GO:0005654=Reactome:REACT_19207, GO:0008270=GO_REF:0000002, GO:0015908=GO_REF:0000024, GO:0045893=PMID:12955147, GO:0030522=PMID:12955147, GO:0060612=GO_REF:0000019, GO:0045892=GO_REF:0000024} Q03181 Peroxisome proliferator-activated receptor delta protein 20130413 {GO:0006629=ISS, GO:0010467=TAS, GO:0051546=IEA, GO:0008284=IEA, GO:0006367=TAS, GO:0003700=IDA, GO:0008283=ISS, GO:0042640=IEA, GO:0045598=IEA, GO:0070539=IDA, GO:0003707=IEA, GO:0050680=IEA, GO:0005634=NAS, GO:0006091=TAS, GO:0008366=ISS, GO:0030154=IEA, GO:0008289=IDA, GO:0009062=TAS, GO:0046697=TAS, GO:0015758=NAS, GO:0008144=IDA, GO:0006006=NAS, GO:0004879=IDA, GO:0008203=TAS, GO:0005504=NAS, GO:0006635=TAS, GO:0006357=TAS, GO:0007566=TAS, GO:0031589=IEA, GO:0006915=IMP, GO:0014068=IEA, GO:0001890=IEA, GO:0000122=ISS, GO:0003677=ISS, GO:0043616=IEA, GO:0043565=IEA, GO:0042060=IEA, GO:0045600=NAS, GO:0005654=TAS, GO:0008270=IEA, GO:0015908=ISS, GO:0045893=IDA, GO:0030522=IDA, GO:0060612=IEA, GO:0045892=ISS} adipose tissue development, anagen, apoptotic process, axon ensheathment, cell differentiation, cell proliferation, cell-substrate adhesion, cholesterol metabolic process, decidualization, embryo implantation, fatty acid beta-oxidation, fatty acid catabolic process, fatty acid transport, gene expression, generation of precursor metabolites and energy, glucose metabolic process, glucose transport, intracellular receptor signaling pathway, keratinocyte migration, keratinocyte proliferation, lipid metabolic process, negative regulation of epithelial cell proliferation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, placenta development, positive regulation of cell proliferation, positive regulation of fat cell differentiation, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of transcription, DNA-dependent, regulation of fat cell differentiation, regulation of transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, wound healing nucleoplasm, nucleus DNA binding, drug binding, fatty acid binding, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, linoleic acid binding, lipid binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity, zinc ion binding Human PPARG UniProtKB UniProtKB {GO:0051974=GO_REF:0000019, GO:0005515=PMID:20195357, GO:0010467=Reactome:REACT_71, GO:0043627=GO_REF:0000019, GO:0030308=GO_REF:0000019, GO:0006367=Reactome:REACT_15525, GO:0003700=GO_REF:0000024, GO:0044212=PMID:18293083, GO:0050544=PMID:9568715, GO:0033189=GO_REF:0000019, GO:0009409=GO_REF:0000019, GO:0003707=GO_REF:0000002, GO:0007507=GO_REF:0000019, GO:0060336=PMID:21268089, GO:0042953=PMID:9568716, GO:0004879=GO_REF:0000002, GO:0071285=GO_REF:0000019, GO:0032869=PMID:10622252, GO:0019395=GO_REF:0000019, GO:0010745=PMID:12700342, GO:0046321=GO_REF:0000019, GO:0000122=GO_REF:0000024, GO:0001890=GO_REF:0000024, GO:0002674=GO_REF:0000019, GO:0055098=PMID:9568716, GO:0045165=GO_REF:0000024, GO:0050872=GO_REF:0000024, GO:0050873=GO_REF:0000019, GO:0045087=PMID:17145956, GO:0045600=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_27277, GO:0045893=GO_REF:0000024, GO:0001012=GO_REF:0000019, GO:0015909=GO_REF:0000024, GO:0019899=PMID:12039952, GO:0045892=GO_REF:0000024, GO:0006629=PMID:9568716, GO:0008285=GO_REF:0000019, GO:0060694=PMID:17611579, GO:0031100=GO_REF:0000019, GO:0033993=PMID:9568715, GO:0010871=PMID:12700342, GO:0005634=GO_REF:0000038, GO:0005829=GO_REF:0000024, GO:0046965=PMID:9568715, GO:0051091=PMID:18293083, GO:0031000=GO_REF:0000019, GO:0030374=PMID:16239304, GO:0008144=PMID:9113987, GO:0045944=PMID:20622039, GO:0030855=GO_REF:0000024, GO:0048469=PMID:9568716, GO:0030224=PMID:9568716, GO:0032526=PMID:16239304, GO:0033613=PMID:10622252, GO:0045713=PMID:9568716, GO:0006919=PMID:18293083, GO:0007584=PMID:10973253, GO:0042493=GO_REF:0000019, GO:0055088=PMID:9113987, GO:0042593=PMID:10622252, GO:0006917=PMID:18293083, GO:0004955=PMID:9568715, GO:0003677=GO_REF:0000024, GO:0010887=PMID:19114110, GO:0043565=GO_REF:0000002, GO:0007165=PMID:9568716, GO:0071407=GO_REF:0000019, GO:0048714=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0010891=PMID:12700342, GO:0008217=PMID:10622252} Q4W448 Peroxisome proliferative activated receptor gamma protein 20130413 {GO:0051974=IEA, GO:0005515=IPI, GO:0010467=TAS, GO:0043627=IEA, GO:0030308=IEA, GO:0006367=TAS, GO:0003700=ISS, GO:0044212=IDA, GO:0050544=ISS, GO:0033189=IEA, GO:0009409=IEA, GO:0003707=IEA, GO:0007507=IEA, GO:0060336=IMP, GO:0042953=IDA, GO:0004879=IEA, GO:0071285=IEA, GO:0032869=IMP, GO:0019395=IEA, GO:0010745=IC, GO:0046321=IEA, GO:0000122=ISS, GO:0001890=ISS, GO:0002674=IEA, GO:0055098=IDA, GO:0045165=ISS, GO:0050872=ISS, GO:0050873=IEA, GO:0045087=TAS, GO:0045600=ISS, GO:0008270=IEA, GO:0005654=TAS, GO:0045893=ISS, GO:0001012=IEA, GO:0015909=ISS, GO:0019899=IPI, GO:0045892=ISS, GO:0006629=TAS, GO:0008285=IEA, GO:0060694=IC, GO:0031100=IEA, GO:0033993=ISS, GO:0010871=IDA, GO:0005634=IEA, GO:0005829=ISS, GO:0046965=IDA, GO:0051091=IDA, GO:0031000=IEA, GO:0030374=IDA, GO:0008144=IDA, GO:0045944=IMP, GO:0030855=ISS, GO:0048469=IDA, GO:0030224=IDA, GO:0032526=IDA, GO:0033613=IDA, GO:0045713=IDA, GO:0006919=IDA, GO:0007584=TAS, GO:0042493=IEA, GO:0055088=TAS, GO:0042593=IMP, GO:0006917=IDA, GO:0004955=TAS, GO:0003677=ISS, GO:0010887=IDA, GO:0043565=IEA, GO:0007165=IDA, GO:0071407=IEA, GO:0048714=IEA, GO:0003682=IEA, GO:0010891=IDA, GO:0008217=IMP} activation of cysteine-type endopeptidase activity involved in apoptotic process, brown fat cell differentiation, cell fate commitment, cell maturation, cellular response to insulin stimulus, cellular response to lithium ion, cellular response to organic cyclic compound, epithelial cell differentiation, fatty acid oxidation, gene expression, glucose homeostasis, heart development, induction of apoptosis, innate immune response, lipid homeostasis, lipid metabolic process, lipoprotein transport, long-chain fatty acid transport, low-density lipoprotein particle receptor biosynthetic process, monocyte differentiation, negative regulation of acute inflammatory response, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of cholesterol storage, negative regulation of interferon-gamma-mediated signaling pathway, negative regulation of macrophage derived foam cell differentiation, negative regulation of receptor biosynthetic process, negative regulation of sequestering of triglyceride, negative regulation of telomerase activity, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, organ regeneration, placenta development, positive regulation of fat cell differentiation, positive regulation of fatty acid oxidation, positive regulation of oligodendrocyte differentiation, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of blood pressure, regulation of cholesterol transporter activity, response to caffeine, response to cold, response to drug, response to estrogen stimulus, response to lipid, response to low-density lipoprotein particle stimulus, response to nutrient, response to retinoic acid, response to vitamin A, signal transduction, transcription initiation from RNA polymerase II promoter, white fat cell differentiation cytosol, nucleoplasm, nucleus DNA binding, RNA polymerase II regulatory region DNA binding, activating transcription factor binding, arachidonic acid binding, chromatin binding, drug binding, enzyme binding, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, ligand-dependent nuclear receptor transcription coactivator activity, prostaglandin receptor activity, protein binding, retinoid X receptor binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity, transcription regulatory region DNA binding, zinc ion binding Human UniProtKB-KW:KW-0539 PPARGC1A BHF-UCL UniProtKB {GO:0008380=PMID:12588810, GO:0001659=PMID:1258810, GO:0006367=PMID:14636573, GO:0001678=PMID:11854298, GO:0003723=PMID:12588810, GO:0006094=PMID:11854298, GO:2000310=GO_REF:0000019, GO:0005634=GO_REF:0000024, GO:0050681=PMID:15572661, GO:0035066=PMID:14636573, GO:0005829=GO_REF:0000019, GO:0051091=PMID:19651776, GO:0043524=GO_REF:0000024, GO:0030374=PMID:16488887, GO:0042594=PMID:11854298, GO:0000166=GO_REF:0000002, GO:0045944=GO_REF:0000024, GO:0005665=PMID:12588810, GO:0010941=PMID:21376232, GO:0006397=PMID:12588810, GO:0016922=PMID:18798693, GO:0001666=GO_REF:0000019, GO:0019395=PMID:11854298, GO:2001171=GO_REF:0000024, GO:0001104=PMID:14636573, GO:0014850=GO_REF:0000024, GO:0010822=GO_REF:0000024, GO:0007586=PMID:10585775, GO:0003713=PMID:19651776, GO:0045722=PMID:12588810, GO:0050821=PMID:14636573, GO:0046321=PMID:12588810, GO:0003677=GO_REF:0000024, GO:0031490=GO_REF:0000024, GO:0022904=GO_REF:0000024, GO:0045333=PMID:11551810, GO:0006461=PMID:14636573, GO:0050873=PMID:12588810, GO:0070997=PMID:21376232, GO:0016605=GO_REF:0000039, GO:0005654=Reactome:REACT_118642, GO:2000507=GO_REF:0000024, GO:0034599=GO_REF:0000024, GO:0007005=PMID:11854298, GO:0045893=PMID:19651776, GO:0030521=PMID:15572661, GO:0008134=PMID:12588810} Q9UBK2 Peroxisome proliferator-activated receptor gamma coactivator 1-alpha protein 20101221 {GO:0008380=TAS, GO:0001659=TAS, GO:0006367=TAS, GO:0001678=NAS, GO:0003723=TAS, GO:0006094=NAS, GO:2000310=IEA, GO:0005634=ISS, GO:0050681=NAS, GO:0035066=TAS, GO:0005829=IEA, GO:0051091=IDA, GO:0043524=ISS, GO:0030374=IDA, GO:0042594=NAS, GO:0000166=IEA, GO:0045944=ISS, GO:0005665=TAS, GO:0010941=IDA, GO:0006397=TAS, GO:0016922=IPI, GO:0001666=IEA, GO:0019395=NAS, GO:2001171=ISS, GO:0001104=TAS, GO:0014850=ISS, GO:0010822=ISS, GO:0007586=TAS, GO:0003713=IDA, GO:0045722=TAS, GO:0050821=TAS, GO:0046321=TAS, GO:0003677=ISS, GO:0031490=ISS, GO:0022904=ISS, GO:0045333=TAS, GO:0006461=TAS, GO:0050873=TAS, GO:0070997=IDA, GO:0016605=IEA, GO:0005654=TAS, GO:2000507=ISS, GO:0034599=ISS, GO:0007005=NAS, GO:0045893=IDA, GO:0030521=NAS, GO:0008134=TAS} RNA splicing, androgen receptor signaling pathway, brown fat cell differentiation, cellular glucose homeostasis, cellular respiration, cellular response to oxidative stress, digestion, fatty acid oxidation, gluconeogenesis, mRNA processing, mitochondrion organization, negative regulation of neuron apoptotic process, neuron death, positive regulation of ATP biosynthetic process, positive regulation of energy homeostasis, positive regulation of fatty acid oxidation, positive regulation of gluconeogenesis, positive regulation of histone acetylation, positive regulation of mitochondrion organization, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein complex assembly, protein stabilization, regulation of N-methyl-D-aspartate selective glutamate receptor activity, regulation of cell death, respiratory electron transport chain, response to hypoxia, response to muscle activity, response to starvation, temperature homeostasis, transcription initiation from RNA polymerase II promoter DNA-directed RNA polymerase II, core complex, PML body, cytosol, nucleoplasm, nucleus DNA binding, RNA binding, RNA polymerase II transcription cofactor activity, androgen receptor binding, chromatin DNA binding, ligand-dependent nuclear receptor binding, ligand-dependent nuclear receptor transcription coactivator activity, nucleotide binding, transcription coactivator activity, transcription factor binding Human UniProtKB:O70343 PPARGC1B GOC UniProtKB {GO:0003723=PMID:11854298, GO:0005634=PMID:11854298, GO:0050682=PMID:11854298, GO:0044281=Reactome:REACT_111217, GO:2000273=PMID:11854298, GO:0051591=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0030374=PMID:11854298, GO:0000166=GO_REF:0000002, GO:0045780=GO_REF:0000019, GO:0045944=PMID:11854298, GO:0007015=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0001104=PMID:11854298, GO:0030331=PMID:11854298, GO:0045672=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0006390=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0060346=GO_REF:0000019, GO:0001503=GO_REF:0000019, GO:0016592=PMID:11854298, GO:0010694=GO_REF:0000019, GO:0030546=PMID:11854298, GO:0034614=GO_REF:0000019, GO:0005654=Reactome:REACT_115949, GO:0045892=GO_REF:0000019, GO:0042327=GO_REF:0000019, GO:0030520=PMID:11854298} Q86YN6 Peroxisome proliferator-activated receptor gamma coactivator 1-beta protein 20130413 {GO:0003723=NAS, GO:0005634=IDA, GO:0050682=IPI, GO:0044281=TAS, GO:2000273=IDA, GO:0051591=IEA, GO:0005739=IEA, GO:0030374=IDA, GO:0000166=IEA, GO:0045780=IEA, GO:0045944=IDA, GO:0007015=IEA, GO:0044255=TAS, GO:0001104=IDA, GO:0030331=IDA, GO:0045672=IEA, GO:0051384=IEA, GO:0006390=IEA, GO:0003676=IEA, GO:0060346=IEA, GO:0001503=IEA, GO:0016592=IDA, GO:0010694=IEA, GO:0030546=IDA, GO:0034614=IEA, GO:0005654=TAS, GO:0045892=IEA, GO:0042327=IEA, GO:0030520=IDA} actin filament organization, bone trabecula formation, cellular lipid metabolic process, cellular response to reactive oxygen species, intracellular estrogen receptor signaling pathway, negative regulation of transcription, DNA-dependent, ossification, positive regulation of alkaline phosphatase activity, positive regulation of bone resorption, positive regulation of osteoclast differentiation, positive regulation of phosphorylation, positive regulation of receptor activity, positive regulation of transcription from RNA polymerase II promoter, response to cAMP, response to glucocorticoid stimulus, small molecule metabolic process, transcription from mitochondrial promoter mediator complex, mitochondrion, nucleoplasm, nucleus AF-2 domain binding, RNA binding, RNA polymerase II transcription cofactor activity, estrogen receptor binding, ligand-dependent nuclear receptor transcription coactivator activity, nucleic acid binding, nucleotide binding, receptor activator activity Human PPAT Reactome UniProtKB {GO:0032869=GO_REF:0000019, GO:0009168=Reactome:REACT_1776, GO:0051539=GO_REF:0000037, GO:0001822=GO_REF:0000019, GO:0060135=GO_REF:0000019, GO:0031100=GO_REF:0000019, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0035690=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_740, GO:0000082=GO_REF:0000019, GO:0007595=GO_REF:0000019, GO:0006144=Reactome:REACT_522, GO:0051289=GO_REF:0000019, GO:0008152=GO_REF:0000002, GO:0009116=GO_REF:0000002, GO:0006543=GO_REF:0000019, GO:0009113=GO_REF:0000002, GO:0004044=GO_REF:0000003, GO:0006164=PMID:8106516, GO:0006189=GO_REF:0000041} Q06203 Amidophosphoribosyltransferase protein 20130213 {GO:0032869=IEA, GO:0009168=TAS, GO:0051539=IEA, GO:0001822=IEA, GO:0060135=IEA, GO:0031100=IEA, GO:0055086=TAS, GO:0044281=TAS, GO:0035690=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0000082=IEA, GO:0007595=IEA, GO:0006144=TAS, GO:0051289=IEA, GO:0008152=IEA, GO:0009116=IEA, GO:0006543=IEA, GO:0009113=IEA, GO:0004044=IEA, GO:0006164=TAS, GO:0006189=IEA} 'de novo' IMP biosynthetic process, G1/S transition of mitotic cell cycle, cellular response to drug, cellular response to insulin stimulus, glutamine catabolic process, kidney development, lactation, maternal process involved in female pregnancy, metabolic process, nucleobase-containing small molecule metabolic process, nucleoside metabolic process, organ regeneration, protein homotetramerization, purine nucleobase biosynthetic process, purine nucleobase metabolic process, purine nucleotide biosynthetic process, purine ribonucleoside monophosphate biosynthetic process, small molecule metabolic process cytosol 4 iron, 4 sulfur cluster binding, amidophosphoribosyltransferase activity, metal ion binding Human PPBP Reactome UniProtKB {GO:0008009=GO_REF:0000002, GO:0043312=GO_REF:0000002, GO:0030593=GO_REF:0000002, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_22289, GO:0005615=GO_REF:0000037, GO:0015758=PMID:4005226, GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0031093=Reactome:REACT_21351, GO:0051781=GO_REF:0000037, GO:0008083=GO_REF:0000037, GO:0042742=GO_REF:0000037, GO:0005355=PMID:4005226} P02775 Platelet basic protein protein 20041006 {GO:0008009=IEA, GO:0043312=IEA, GO:0030593=IEA, GO:0030168=TAS, GO:0005576=TAS, GO:0005615=IEA, GO:0015758=TAS, GO:0007596=TAS, GO:0002576=TAS, GO:0031093=TAS, GO:0051781=IEA, GO:0008083=IEA, GO:0042742=IEA, GO:0005355=TAS} blood coagulation, defense response to bacterium, glucose transport, neutrophil chemotaxis, neutrophil degranulation, platelet activation, platelet degranulation, positive regulation of cell division extracellular region, extracellular space, platelet alpha granule lumen chemokine activity, glucose transmembrane transporter activity, growth factor activity Human PPCDC Reactome UniProtKB {GO:0015939=Reactome:REACT_11172, GO:0006766=Reactome:REACT_11193, GO:0006767=Reactome:REACT_11238, GO:0009108=Reactome:REACT_11218, GO:0015937=PMID:11923312, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0005829=Reactome:REACT_11231, GO:0004633=Reactome:REACT_11231} Q96CD2 Phosphopantothenoylcysteine decarboxylase protein 20130222 {GO:0015939=TAS, GO:0006766=TAS, GO:0006767=TAS, GO:0009108=TAS, GO:0015937=IDA, GO:0044281=TAS, GO:0003824=IEA, GO:0005829=TAS, GO:0004633=TAS} coenzyme A biosynthetic process, coenzyme biosynthetic process, pantothenate metabolic process, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cytosol catalytic activity, phosphopantothenoylcysteine decarboxylase activity Human PPCS Reactome UniProtKB {GO:0015939=Reactome:REACT_11172, GO:0006766=Reactome:REACT_11193, GO:0004632=Reactome:REACT_11112, GO:0006767=Reactome:REACT_11238, GO:0009108=Reactome:REACT_11218, GO:0015937=PMID:11923312, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_11112} Q9HAB8 Phosphopantothenate--cysteine ligase protein 20130222 {GO:0015939=TAS, GO:0006766=TAS, GO:0004632=TAS, GO:0006767=TAS, GO:0009108=TAS, GO:0015937=IDA, GO:0044281=TAS, GO:0005829=TAS} coenzyme A biosynthetic process, coenzyme biosynthetic process, pantothenate metabolic process, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cytosol phosphopantothenate--cysteine ligase activity Human PPDPF UniProtKB UniProtKB {GO:0007275=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q9H3Y8 Pancreatic progenitor cell differentiation and proliferation factor protein 20130413 {GO:0007275=IEA, GO:0030154=IEA} cell differentiation, multicellular organismal development Human UniProtKB-KW:KW-0221 PPEF1 IntAct UniProtKB {GO:0005515=PMID:12051765, GO:0006470=PMID:9215685, GO:0050906=GO_REF:0000002, GO:0030145=GO_REF:0000002, GO:0005506=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0004721=GO_REF:0000003, GO:0004722=PMID:9215685} O14829 Serine/threonine-protein phosphatase with EF-hands 1 protein 20130415 {GO:0005515=IPI, GO:0006470=TAS, GO:0050906=IEA, GO:0030145=IEA, GO:0005506=IEA, GO:0005509=IEA, GO:0004721=IEA, GO:0004722=TAS} detection of stimulus involved in sensory perception, protein dephosphorylation calcium ion binding, iron ion binding, manganese ion binding, phosphoprotein phosphatase activity, protein binding, protein serine/threonine phosphatase activity Human UniProtKB:P62204 PPEF2 BHF-UCL UniProtKB {GO:0005515=PMID:12051765, GO:0030145=GO_REF:0000002, GO:0005506=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0051879=PMID:20674765, GO:0031435=PMID:20674765, GO:0010801=PMID:20674765, GO:0043409=PMID:20674765, GO:0001917=GO_REF:0000039, GO:0005737=GO_REF:0000039, GO:0050906=GO_REF:0000002, GO:0006470=PMID:9326663, GO:0043405=PMID:20674765, GO:0030544=PMID:20674765, GO:0043506=PMID:20674765, GO:0004722=PMID:9326663, GO:0007601=GO_REF:0000037, GO:0001750=GO_REF:0000039} O14830 Serine/threonine-protein phosphatase with EF-hands 2 protein 20110428 {GO:0005515=IPI, GO:0030145=IEA, GO:0005506=IEA, GO:0005509=IEA, GO:0051879=IDA, GO:0031435=IPI, GO:0010801=IDA, GO:0043409=IDA, GO:0001917=IEA, GO:0005737=IEA, GO:0050906=IEA, GO:0006470=TAS, GO:0043405=IC, GO:0030544=IDA, GO:0043506=IC, GO:0004722=TAS, GO:0007601=IEA, GO:0001750=IEA} detection of stimulus involved in sensory perception, negative regulation of MAPK cascade, negative regulation of peptidyl-threonine phosphorylation, protein dephosphorylation, regulation of JUN kinase activity, regulation of MAP kinase activity, visual perception cytoplasm, photoreceptor inner segment, photoreceptor outer segment Hsp70 protein binding, Hsp90 protein binding, calcium ion binding, iron ion binding, manganese ion binding, mitogen-activated protein kinase kinase kinase binding, protein binding, protein serine/threonine phosphatase activity Human PPFIA1 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0007165=PMID:7796809, GO:0005737=GO_REF:0000039, GO:0007160=PMID:7796809, GO:0004871=PMID:7796809} Q13136 Liprin-alpha-1 protein 20130415 {GO:0005515=IPI, GO:0007165=TAS, GO:0005737=IEA, GO:0007160=TAS, GO:0004871=TAS} cell-matrix adhesion, signal transduction cytoplasm protein binding, signal transducer activity Human UniProtKB:Q9NS73 PPFIA2 PINC UniProtKB {GO:0005515=PMID:12923177, GO:0005737=GO_REF:0000039, GO:0007160=PMID:9624153, GO:0009986=GO_REF:0000039, GO:0045202=GO_REF:0000019} O75334 Liprin-alpha-2 protein 20030904 {GO:0005515=IPI, GO:0005737=IEA, GO:0007160=TAS, GO:0009986=IEA, GO:0045202=IEA} cell-matrix adhesion cell surface, cytoplasm, synapse protein binding Human PPFIA3 UniProtKB UniProtKB {GO:0005515=PMID:12923177, GO:0005737=GO_REF:0000039, GO:0009986=GO_REF:0000039} O75145 Liprin-alpha-3 protein 20051018 {GO:0005515=IPI, GO:0005737=IEA, GO:0009986=IEA} cell surface, cytoplasm protein binding Human UniProtKB:O15083 PPFIA4 UniProtKB UniProtKB {GO:0005515=PMID:12923177, GO:0005622=PMID:9624153, GO:0005737=GO_REF:0000039, GO:0007154=GO_REF:0000029, GO:0009986=GO_REF:0000039} O75335 Liprin-alpha-4 protein 20051018 {GO:0005515=IPI, GO:0005622=TAS, GO:0005737=IEA, GO:0007154=NAS, GO:0009986=IEA} cell communication cell surface, cytoplasm, intracellular protein binding Human UniProtKB:O15083 PPFIBP1 PINC UniProtKB {GO:0005886=PMID:9624153, GO:0007155=PMID:9624153} Q86W92 Liprin-beta-1 protein 20050308 {GO:0005886=NAS, GO:0007155=TAS} cell adhesion plasma membrane Human PPFIBP2 UniProtKB UniProtKB {GO:0005622=PMID:9624153, GO:0008907=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0007154=GO_REF:0000029, GO:0003677=GO_REF:0000002} Q8ND30 Liprin-beta-2 protein 20061026 {GO:0005622=TAS, GO:0008907=IEA, GO:0003674=ND, GO:0007154=NAS, GO:0003677=IEA} cell communication intracellular DNA binding, integrase activity, molecular_function Human PPHLN1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0031424=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q8NEY8 Periphilin-1 protein 20110516 {GO:0005737=IDA, GO:0031424=IEA, GO:0005730=IDA, GO:0005634=IDA} keratinization cytoplasm, nucleolus, nucleus Human PPIA UniProtKB UniProtKB {GO:0019076=PMID:21711559, GO:0000413=PMID:14993672, GO:0005515=PMID:16273344, GO:0022415=Reactome:REACT_6266, GO:0030260=Reactome:REACT_6903, GO:0050714=PMID:21711559, GO:0045069=PMID:7590732, GO:0005634=PMID:16780588, GO:0050900=Reactome:REACT_12051, GO:0005829=Reactome:REACT_9444, GO:0006457=GO_REF:0000038, GO:0016032=Reactome:REACT_6256, GO:0006278=Reactome:REACT_9055, GO:0045070=PMID:19932913, GO:0042277=GO_REF:0000037, GO:0019061=Reactome:REACT_6965, GO:0003755=GO_REF:0000038, GO:0046790=PMID:11250896, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_12497, GO:0034389=PMID:21711559, GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0051082=PMID:2644542, GO:0075713=Reactome:REACT_6918} Q567Q0 Peptidyl-prolyl cis-trans isomerase A protein 20130413 {GO:0019076=TAS, GO:0000413=IDA, GO:0005515=IPI, GO:0022415=TAS, GO:0030260=TAS, GO:0050714=IMP, GO:0045069=TAS, GO:0005634=IDA, GO:0050900=TAS, GO:0005829=TAS, GO:0006457=IEA, GO:0016032=TAS, GO:0006278=TAS, GO:0045070=IMP, GO:0042277=IEA, GO:0019061=TAS, GO:0003755=IEA, GO:0046790=NAS, GO:0030168=TAS, GO:0005576=TAS, GO:0034389=IMP, GO:0007596=TAS, GO:0002576=TAS, GO:0051082=TAS, GO:0075713=TAS} RNA-dependent DNA replication, blood coagulation, entry into host cell, establishment of integrated proviral latency, leukocyte migration, lipid particle organization, platelet activation, platelet degranulation, positive regulation of protein secretion, positive regulation of viral genome replication, protein folding, protein peptidyl-prolyl isomerization, regulation of viral genome replication, uncoating of virus, viral release from host cell, viral reproduction, viral reproductive process cytosol, extracellular region, nucleus peptide binding, peptidyl-prolyl cis-trans isomerase activity, protein binding, unfolded protein binding, virion binding Human UniProtKB-KW:KW-0697 PPIAL4A UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0006457=GO_REF:0000037, GO:0003755=GO_REF:0000003} Q9Y536 Peptidyl-prolyl cis-trans isomerase A-like 4A/B/C protein 20130413 {GO:0005737=IEA, GO:0006457=IEA, GO:0003755=IEA} protein folding cytoplasm peptidyl-prolyl cis-trans isomerase activity Human UniProtKB-SubCell:SL-0086 PPIB GOC UniProtKB {GO:0000413=PMID:2000394, GO:0005515=PMID:15095401, GO:0042470=GO_REF:0000039, GO:0042277=GO_REF:0000037, GO:0030198=Reactome:REACT_118779, GO:0005783=PMID:2000394, GO:0006457=GO_REF:0000037, GO:0003755=PMID:2000394, GO:0005788=Reactome:REACT_120939, GO:0051082=PMID:2000394} P23284 Peptidyl-prolyl cis-trans isomerase B protein 20130413 {GO:0000413=NAS, GO:0005515=IPI, GO:0042470=IEA, GO:0042277=IEA, GO:0030198=TAS, GO:0005783=TAS, GO:0006457=IEA, GO:0003755=NAS, GO:0005788=TAS, GO:0051082=TAS} extracellular matrix organization, protein folding, protein peptidyl-prolyl isomerization endoplasmic reticulum, endoplasmic reticulum lumen, melanosome peptide binding, peptidyl-prolyl cis-trans isomerase activity, protein binding, unfolded protein binding Human PPIC PINC UniProtKB {GO:0007165=PMID:1652374, GO:0016018=PMID:1652374, GO:0005737=GO_REF:0000039, GO:0006457=GO_REF:0000037, GO:0003755=GO_REF:0000003, GO:0051082=PMID:1652374} P45877 Peptidyl-prolyl cis-trans isomerase C protein 20040806 {GO:0007165=TAS, GO:0016018=TAS, GO:0005737=IEA, GO:0006457=IEA, GO:0003755=IEA, GO:0051082=TAS} protein folding, signal transduction cytoplasm cyclosporin A binding, peptidyl-prolyl cis-trans isomerase activity, unfolded protein binding Human PPID GOC UniProtKB {GO:0000413=PMID:11350175, GO:0019076=PMID:21711559, GO:0005515=PMID:16507998, GO:0051879=PMID:12145316, GO:0050714=PMID:21711559, GO:0005634=PMID:11525244, GO:0015031=GO_REF:0000037, GO:0005737=PMID:11525244, GO:0006457=GO_REF:0000024, GO:0031072=PMID:9660753, GO:0045111=GO_REF:0000052, GO:0045070=PMID:19932913, GO:0016018=PMID:7744028, GO:0043065=PMID:23220213, GO:0030331=GO_REF:0000024, GO:0003755=PMID:11350175, GO:0005730=PMID:11525244, GO:0071492=PMID:23220213, GO:0006915=GO_REF:0000037, GO:0000122=PMID:18708059, GO:0034389=PMID:21711559, GO:0006461=PMID:18708059, GO:0061077=PMID:11350175, GO:0030544=GO_REF:0000024, GO:0005654=GO_REF:0000039, GO:0008134=PMID:9659917} Q08752 Peptidyl-prolyl cis-trans isomerase D protein 20130413 {GO:0000413=IDA, GO:0019076=TAS, GO:0005515=IPI, GO:0051879=IDA, GO:0050714=IMP, GO:0005634=IDA, GO:0015031=IEA, GO:0005737=IDA, GO:0006457=ISS, GO:0031072=IPI, GO:0045111=IDA, GO:0045070=IMP, GO:0016018=TAS, GO:0043065=IMP, GO:0030331=ISS, GO:0003755=IDA, GO:0005730=IDA, GO:0071492=IMP, GO:0006915=IEA, GO:0000122=IMP, GO:0034389=IMP, GO:0006461=IDA, GO:0061077=IDA, GO:0030544=ISS, GO:0005654=IEA, GO:0008134=IDA} apoptotic process, cellular response to UV-A, chaperone-mediated protein folding, lipid particle organization, negative regulation of transcription from RNA polymerase II promoter, positive regulation of apoptotic process, positive regulation of protein secretion, positive regulation of viral genome replication, protein complex assembly, protein folding, protein peptidyl-prolyl isomerization, protein transport, viral release from host cell cytoplasm, intermediate filament cytoskeleton, nucleolus, nucleoplasm, nucleus Hsp70 protein binding, Hsp90 protein binding, cyclosporin A binding, estrogen receptor binding, heat shock protein binding, peptidyl-prolyl cis-trans isomerase activity, protein binding, transcription factor binding Human PPIE GOC UniProtKB {GO:0005515=PMID:20541251, GO:0000413=PMID:11313484, GO:0006355=PMID:11313484, GO:0016018=PMID:9747881, GO:0003723=PMID:11313484, GO:0003755=PMID:11313484, GO:0005634=PMID:11313484, GO:0003676=GO_REF:0000002, GO:0071013=PMID:11991638, GO:0000166=GO_REF:0000002, GO:0006457=GO_REF:0000037, GO:0000398=PMID:11991638, GO:0045070=PMID:19932913} Q9UNP9 Peptidyl-prolyl cis-trans isomerase E protein 20130413 {GO:0005515=IPI, GO:0000413=TAS, GO:0006355=IMP, GO:0016018=TAS, GO:0003723=TAS, GO:0003755=TAS, GO:0005634=IDA, GO:0003676=IEA, GO:0071013=IDA, GO:0000166=IEA, GO:0006457=IEA, GO:0000398=IC, GO:0045070=IMP} mRNA splicing, via spliceosome, positive regulation of viral genome replication, protein folding, protein peptidyl-prolyl isomerization, regulation of transcription, DNA-dependent catalytic step 2 spliceosome, nucleus RNA binding, cyclosporin A binding, nucleic acid binding, nucleotide binding, peptidyl-prolyl cis-trans isomerase activity, protein binding Human PPIF UniProtKB UniProtKB {GO:0046902=GO_REF:0000024, GO:0016018=GO_REF:0000019, GO:0043066=PMID:19228691, GO:0010849=GO_REF:0000024, GO:0070301=PMID:22726440, GO:0003755=GO_REF:0000003, GO:0090324=GO_REF:0000024, GO:0032780=GO_REF:0000024, GO:2001243=PMID:19228691, GO:0005753=GO_REF:0000024, GO:0008637=GO_REF:0000019, GO:0016020=PMID:1744118, GO:0090201=PMID:19228691, GO:0006457=GO_REF:0000038, GO:0005759=GO_REF:0000039, GO:0002931=GO_REF:0000024, GO:0090200=GO_REF:0000024, GO:0071277=GO_REF:0000024, GO:2000276=GO_REF:0000024, GO:0071243=GO_REF:0000024, GO:0010940=PMID:22726440} Q2YDB7 Peptidyl-prolyl cis-trans isomerase protein 20130413 {GO:0046902=ISS, GO:0016018=IEA, GO:0043066=IDA, GO:0010849=ISS, GO:0070301=IMP, GO:0003755=IEA, GO:0090324=ISS, GO:0032780=ISS, GO:2001243=IMP, GO:0005753=ISS, GO:0008637=IEA, GO:0016020=TAS, GO:0090201=IDA, GO:0006457=IEA, GO:0005759=IEA, GO:0002931=ISS, GO:0090200=ISS, GO:0071277=ISS, GO:2000276=ISS, GO:0071243=ISS, GO:0010940=IMP} apoptotic mitochondrial changes, cellular response to arsenic-containing substance, cellular response to calcium ion, cellular response to hydrogen peroxide, negative regulation of ATPase activity, negative regulation of apoptotic process, negative regulation of intrinsic apoptotic signaling pathway, negative regulation of oxidative phosphorylation, negative regulation of oxidative phosphorylation uncoupler activity, negative regulation of release of cytochrome c from mitochondria, positive regulation of necrotic cell death, positive regulation of release of cytochrome c from mitochondria, protein folding, regulation of mitochondrial membrane permeability, regulation of proton-transporting ATPase activity, rotational mechanism, response to ischemia membrane, mitochondrial matrix, mitochondrial proton-transporting ATP synthase complex cyclosporin A binding, peptidyl-prolyl cis-trans isomerase activity Human EC:5.2.1.8 PPIG HPA UniProtKB {GO:0008380=PMID:9153302, GO:0016018=PMID:9153302, GO:0005737=GO_REF:0000052, GO:0016607=GO_REF:0000039, GO:0006457=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0003755=GO_REF:0000003, GO:0005654=PMID:9153302, GO:0005634=GO_REF:0000052, GO:0016363=GO_REF:0000039} Q13427 Peptidyl-prolyl cis-trans isomerase G protein 20111111 {GO:0008380=TAS, GO:0016018=TAS, GO:0005737=IDA, GO:0016607=IEA, GO:0006457=IEA, GO:0005730=IDA, GO:0003755=IEA, GO:0005654=TAS, GO:0005634=IDA, GO:0016363=IEA} RNA splicing, protein folding cytoplasm, nuclear matrix, nuclear speck, nucleolus, nucleoplasm, nucleus cyclosporin A binding, peptidyl-prolyl cis-trans isomerase activity Human PPIH GOC UniProtKB {GO:0000413=PMID:9570313, GO:0005515=PMID:9570313, GO:0016018=PMID:9570313, GO:0003755=PMID:9570313, GO:0071001=PMID:9570313, GO:0005737=PMID:9570313, GO:0006461=PMID:9570313, GO:0016607=PMID:9570313, GO:0006457=GO_REF:0000037, GO:0000398=PMID:9570313, GO:0043021=PMID:9570313, GO:0005681=PMID:9570313, GO:0046540=PMID:9570313, GO:0045070=PMID:19932913} O43447 Peptidyl-prolyl cis-trans isomerase H protein 20130413 {GO:0000413=IDA, GO:0005515=IPI, GO:0016018=TAS, GO:0003755=IDA, GO:0071001=IDA, GO:0005737=IDA, GO:0006461=TAS, GO:0016607=IDA, GO:0006457=IEA, GO:0000398=IC, GO:0043021=IDA, GO:0005681=IC, GO:0046540=IDA, GO:0045070=IMP} mRNA splicing, via spliceosome, positive regulation of viral genome replication, protein complex assembly, protein folding, protein peptidyl-prolyl isomerization U4/U6 snRNP, U4/U6 x U5 tri-snRNP complex, cytoplasm, nuclear speck, spliceosomal complex cyclosporin A binding, peptidyl-prolyl cis-trans isomerase activity, protein binding, ribonucleoprotein complex binding Human PPIL1 IntAct UniProtKB {GO:0005515=PMID:20368803, GO:0000398=PMID:11991638, GO:0006457=GO_REF:0000037, GO:0003755=GO_REF:0000003, GO:0071013=PMID:11991638} Q9Y3C6 Peptidyl-prolyl cis-trans isomerase-like 1 protein 20130415 {GO:0005515=IPI, GO:0000398=IC, GO:0006457=IEA, GO:0003755=IEA, GO:0071013=IDA} mRNA splicing, via spliceosome, protein folding catalytic step 2 spliceosome peptidyl-prolyl cis-trans isomerase activity, protein binding Human UniProtKB:Q13573 PPIL2 HPA UniProtKB {GO:0000209=PMID:11435423, GO:0004842=PMID:11435423, GO:0007596=Reactome:REACT_604, GO:0005796=Reactome:REACT_12550, GO:0006457=GO_REF:0000037, GO:0034450=PMID:11435423, GO:0005730=GO_REF:0000052, GO:0003755=GO_REF:0000003, GO:0000151=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0050900=Reactome:REACT_12051} Q13356 Peptidyl-prolyl cis-trans isomerase-like 2 protein 20101115 {GO:0000209=IDA, GO:0004842=IDA, GO:0007596=TAS, GO:0005796=TAS, GO:0006457=IEA, GO:0034450=IDA, GO:0005730=IDA, GO:0003755=IEA, GO:0000151=IEA, GO:0005634=IDA, GO:0050900=TAS} blood coagulation, leukocyte migration, protein folding, protein polyubiquitination Golgi lumen, nucleolus, nucleus, ubiquitin ligase complex peptidyl-prolyl cis-trans isomerase activity, ubiquitin-protein ligase activity, ubiquitin-ubiquitin ligase activity NOT Human PPIL3 IntAct UniProtKB {GO:0005515=PMID:18474220, GO:0000398=PMID:11991638, GO:0006457=GO_REF:0000037, GO:0003755=GO_REF:0000003, GO:0071013=PMID:11991638} Q9H2H8 Peptidyl-prolyl cis-trans isomerase-like 3 protein 20130415 {GO:0005515=IPI, GO:0000398=IC, GO:0006457=IEA, GO:0003755=IEA, GO:0071013=IDA} mRNA splicing, via spliceosome, protein folding catalytic step 2 spliceosome peptidyl-prolyl cis-trans isomerase activity, protein binding Human UniProtKB:Q99152 PPIL4 UniProtKB UniProtKB {GO:0000166=GO_REF:0000002, GO:0006457=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0003755=GO_REF:0000003, GO:0005634=GO_REF:0000039} Q8WUA2 Peptidyl-prolyl cis-trans isomerase-like 4 protein 20130413 {GO:0000166=IEA, GO:0006457=IEA, GO:0003723=IEA, GO:0003755=IEA, GO:0005634=IEA} protein folding nucleus RNA binding, nucleotide binding, peptidyl-prolyl cis-trans isomerase activity Human UniProtKB-SubCell:SL-0191 PPIP5K1 HPA UniProtKB {GO:0000827=PMID:17412958, GO:0006020=PMID:17412958, GO:0033857=PMID:17412958, GO:0043647=Reactome:REACT_150188, GO:0005886=GO_REF:0000039, GO:0003993=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0052724=GO_REF:0000003, GO:0005634=GO_REF:0000052, GO:0052723=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0000832=PMID:17412958, GO:0005829=Reactome:REACT_150370, GO:0005737=GO_REF:0000052, GO:0016301=GO_REF:0000037} Q6PFW1 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 protein 20110516 {GO:0000827=IDA, GO:0006020=IDA, GO:0033857=IDA, GO:0043647=TAS, GO:0005886=IEA, GO:0003993=IEA, GO:0005730=IDA, GO:0052724=IEA, GO:0005634=IDA, GO:0052723=IEA, GO:0044281=TAS, GO:0005524=IEA, GO:0000832=IDA, GO:0005829=TAS, GO:0005737=IDA, GO:0016301=IEA} inositol metabolic process, inositol phosphate metabolic process, small molecule metabolic process cytoplasm, cytosol, nucleolus, nucleus, plasma membrane ATP binding, acid phosphatase activity, diphosphoinositol-pentakisphosphate kinase activity, inositol hexakisphosphate 1-kinase activity, inositol hexakisphosphate 3-kinase activity, inositol hexakisphosphate 5-kinase activity, inositol-1,3,4,5,6-pentakisphosphate kinase activity, kinase activity Human PPIP5K2 Reactome UniProtKB {GO:0033857=GO_REF:0000024, GO:0006020=GO_REF:0000024, GO:0000827=GO_REF:0000024, GO:0043647=Reactome:REACT_150188, GO:0016301=GO_REF:0000037, GO:0003993=GO_REF:0000002, GO:0052724=GO_REF:0000003, GO:0052723=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0000832=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_150370} O43314 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 protein 20130301 {GO:0033857=ISS, GO:0006020=ISS, GO:0000827=ISS, GO:0043647=TAS, GO:0016301=IEA, GO:0003993=IEA, GO:0052724=IEA, GO:0052723=IEA, GO:0044281=TAS, GO:0000832=ISS, GO:0005524=IEA, GO:0005829=TAS} inositol metabolic process, inositol phosphate metabolic process, small molecule metabolic process cytosol ATP binding, acid phosphatase activity, diphosphoinositol-pentakisphosphate kinase activity, inositol hexakisphosphate 1-kinase activity, inositol hexakisphosphate 3-kinase activity, inositol hexakisphosphate 5-kinase activity, inositol-1,3,4,5,6-pentakisphosphate kinase activity, kinase activity Human PPL IntAct UniProtKB {GO:0005515=PMID:18624398, GO:0030057=GO_REF:0000039, GO:0005739=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0005200=PMID:9521878, GO:0031424=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0005856=GO_REF:0000039} O60437 Periplakin protein 20130415 {GO:0005515=IPI, GO:0030057=IEA, GO:0005739=IEA, GO:0005886=IEA, GO:0005200=TAS, GO:0031424=IEA, GO:0005634=IEA, GO:0005856=IEA} keratinization cytoskeleton, desmosome, mitochondrion, nucleus, plasma membrane protein binding, structural constituent of cytoskeleton Human UniProtKB:P31749 PPM1A BHF-UCL UniProtKB {GO:0005515=PMID:10644691, GO:0008286=Reactome:REACT_498, GO:0010467=Reactome:REACT_71, GO:0043005=GO_REF:0000019, GO:0010991=PMID:16751101, GO:0006367=Reactome:REACT_12627, GO:0030177=PMID:10644691, GO:0005634=PMID:16751101, GO:0003824=GO_REF:0000002, GO:0046872=GO_REF:0000038, GO:0005829=Reactome:REACT_21418, GO:0006470=GO_REF:0000019, GO:0007050=Reactome:REACT_21387, GO:0007179=Reactome:REACT_6844, GO:0004871=PMID:12761501, GO:0004722=Reactome:REACT_121342, GO:0016055=PMID:10644691, GO:0043123=PMID:12761501, GO:0030512=PMID:16751101, GO:0033192=PMID:11559703, GO:0030145=GO_REF:0000002, GO:0000287=GO_REF:0000002, GO:0070412=PMID:16751101, GO:0000122=Reactome:REACT_121111, GO:0008022=GO_REF:0000019, GO:0005891=GO_REF:0000019, GO:0006351=Reactome:REACT_121061, GO:0016311=PMID:10644691, GO:0005654=Reactome:REACT_121342, GO:0045893=PMID:10644691} P35813 Protein phosphatase 1A protein 20080919 {GO:0005515=IPI, GO:0008286=TAS, GO:0010467=TAS, GO:0043005=IEA, GO:0010991=IDA, GO:0006367=TAS, GO:0030177=IDA, GO:0005634=IDA, GO:0003824=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0006470=IEA, GO:0007050=TAS, GO:0007179=TAS, GO:0004871=IMP, GO:0004722=TAS, GO:0016055=IDA, GO:0043123=IMP, GO:0030512=IDA, GO:0033192=IDA, GO:0030145=IEA, GO:0000287=IEA, GO:0070412=IPI, GO:0000122=TAS, GO:0008022=IEA, GO:0005891=IEA, GO:0006351=TAS, GO:0016311=IDA, GO:0005654=TAS, GO:0045893=IDA} Wnt receptor signaling pathway, cell cycle arrest, dephosphorylation, gene expression, insulin receptor signaling pathway, negative regulation of SMAD protein complex assembly, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transforming growth factor beta receptor signaling pathway, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of Wnt receptor signaling pathway, positive regulation of transcription, DNA-dependent, protein dephosphorylation, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway cytosol, neuron projection, nucleoplasm, nucleus, voltage-gated calcium channel complex R-SMAD binding, calmodulin-dependent protein phosphatase activity, catalytic activity, magnesium ion binding, manganese ion binding, metal ion binding, protein C-terminus binding, protein binding, protein serine/threonine phosphatase activity, signal transducer activity Human UniProtKB:Q92997 PPM1B IntAct UniProtKB {GO:0005515=PMID:17620599, GO:0030145=GO_REF:0000002, GO:0006470=PMID:9684878, GO:0000287=GO_REF:0000002, GO:0019221=Reactome:REACT_25229, GO:0004722=PMID:20801214, GO:0005829=Reactome:REACT_115843} O75688 Protein phosphatase 1B protein 20130415 {GO:0005515=IPI, GO:0030145=IEA, GO:0006470=TAS, GO:0000287=IEA, GO:0019221=TAS, GO:0004722=IDA, GO:0005829=TAS} cytokine-mediated signaling pathway, protein dephosphorylation cytosol magnesium ion binding, manganese ion binding, protein binding, protein serine/threonine phosphatase activity Human UniProtKB:P49407 PPM1D UniProtKB UniProtKB {GO:0005515=PMID:17936559, GO:0009314=PMID:9177166, GO:0009617=GO_REF:0000019, GO:0008285=PMID:9177166, GO:0006470=GO_REF:0000002, GO:0000086=GO_REF:0000019, GO:0005634=PMID:9177166, GO:0004722=GO_REF:0000002, GO:0003824=GO_REF:0000002, GO:0046872=GO_REF:0000038} Q8IVR6 Protein phosphatase 1D magnesium-dependent, delta isoform, isoform CRA_b protein 20130413 {GO:0005515=IPI, GO:0009314=TAS, GO:0009617=IEA, GO:0008285=TAS, GO:0006470=IEA, GO:0000086=IEA, GO:0005634=TAS, GO:0004722=IEA, GO:0003824=IEA, GO:0046872=IEA} G2/M transition of mitotic cell cycle, negative regulation of cell proliferation, protein dephosphorylation, response to bacterium, response to radiation nucleus catalytic activity, metal ion binding, protein binding, protein serine/threonine phosphatase activity Human UniProtKB-KW:KW-0479 PPM1E HPA UniProtKB {GO:0005515=PMID:11864573, GO:0043234=PMID:11864573, GO:0005737=GO_REF:0000039, GO:0051496=PMID:11864573, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0004722=PMID:20801214, GO:0046872=GO_REF:0000037} Q8WY54 Protein phosphatase 1E protein 20090616 {GO:0005515=IPI, GO:0043234=IDA, GO:0005737=IEA, GO:0051496=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0004722=IDA, GO:0046872=IEA} positive regulation of stress fiber assembly cytoplasm, nucleolus, nucleus, protein complex metal ion binding, protein binding, protein serine/threonine phosphatase activity Human PPM1F UniProtKB UniProtKB {GO:0005515=PMID:11559703, GO:0048471=GO_REF:0000019, GO:0010811=PMID:20016286, GO:0051894=PMID:20016286, GO:0046872=GO_REF:0000037, GO:0097193=PMID:11559703, GO:0005829=PMID:11559703, GO:0043280=PMID:11559703, GO:0043234=PMID:11864573, GO:0016791=PMID:15140879, GO:0006470=GO_REF:0000002, GO:0050921=PMID:20016286, GO:0016301=GO_REF:0000038, GO:0051496=PMID:11864573, GO:0004722=PMID:11864573, GO:0010634=PMID:20016286, GO:0045927=PMID:20016286, GO:0033192=PMID:11559703} P49593 Protein phosphatase 1F protein 20120124 {GO:0005515=IPI, GO:0048471=IEA, GO:0010811=IMP, GO:0051894=IMP, GO:0046872=IEA, GO:0097193=IDA, GO:0005829=IDA, GO:0043280=IDA, GO:0043234=IDA, GO:0016791=IDA, GO:0006470=IEA, GO:0050921=IMP, GO:0016301=IEA, GO:0051496=IDA, GO:0004722=IDA, GO:0010634=IMP, GO:0045927=IMP, GO:0033192=IDA} intrinsic apoptotic signaling pathway, positive regulation of cell-substrate adhesion, positive regulation of chemotaxis, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of epithelial cell migration, positive regulation of focal adhesion assembly, positive regulation of growth, positive regulation of stress fiber assembly, protein dephosphorylation cytosol, perinuclear region of cytoplasm, protein complex calmodulin-dependent protein phosphatase activity, kinase activity, metal ion binding, phosphatase activity, protein binding, protein serine/threonine phosphatase activity Human PPM1G HPA UniProtKB {GO:0005515=PMID:22190034, GO:0005737=GO_REF:0000039, GO:0006470=PMID:9276438, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0007050=GO_REF:0000019, GO:0004722=PMID:20801214, GO:0046872=GO_REF:0000037} O15355 Protein phosphatase 1G protein 20111111 {GO:0005515=IPI, GO:0005737=IEA, GO:0006470=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0007050=IEA, GO:0004722=IDA, GO:0046872=IEA} cell cycle arrest, protein dephosphorylation cytoplasm, nucleolus, nucleus metal ion binding, protein binding, protein serine/threonine phosphatase activity NOT Human PPM1J ENSEMBL UniProtKB {GO:0006470=GO_REF:0000019, GO:0004722=GO_REF:0000019} Q5JR12 Protein phosphatase 1J protein 20130413 {GO:0006470=IEA, GO:0004722=IEA} protein dephosphorylation protein serine/threonine phosphatase activity Human Ensembl:ENSMUSP00000002298 PPM1K HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0006470=GO_REF:0000002, GO:0005759=GO_REF:0000039, GO:0004722=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q8N3J5 Protein phosphatase 1K, mitochondrial protein 20100326 {GO:0005739=IDA, GO:0006470=IEA, GO:0005759=IEA, GO:0004722=IEA, GO:0046872=IEA} protein dephosphorylation mitochondrial matrix, mitochondrion metal ion binding, protein serine/threonine phosphatase activity Human PPM1L Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0006470=GO_REF:0000002, GO:0000165=GO_REF:0000019, GO:0030148=Reactome:REACT_115810, GO:0005789=Reactome:REACT_19306, GO:0007178=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0004722=Reactome:REACT_19304, GO:0016021=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q5SGD2 Protein phosphatase 1L protein 20130213 {GO:0006665=TAS, GO:0006470=IEA, GO:0000165=IEA, GO:0030148=TAS, GO:0005789=TAS, GO:0007178=IEA, GO:0044281=TAS, GO:0004722=TAS, GO:0016021=IEA, GO:0046872=IEA} MAPK cascade, protein dephosphorylation, small molecule metabolic process, sphingolipid biosynthetic process, sphingolipid metabolic process, transmembrane receptor protein serine/threonine kinase signaling pathway endoplasmic reticulum membrane, integral to membrane metal ion binding, protein serine/threonine phosphatase activity Human PPME1 PINC UniProtKB {GO:0004091=GO_REF:0000037, GO:0019901=GO_REF:0000019, GO:0004864=PMID:10318862, GO:0019903=PMID:10318862, GO:0008601=PMID:10318862, GO:0006482=PMID:10318862, GO:0051722=PMID:10318862, GO:0051721=PMID:10318862} Q9Y570 Protein phosphatase methylesterase 1 protein 20030904 {GO:0004091=IEA, GO:0019901=IEA, GO:0004864=TAS, GO:0019903=IDA, GO:0008601=TAS, GO:0006482=IDA, GO:0051722=IDA, GO:0051721=IDA} protein demethylation carboxylesterase activity, protein C-terminal methylesterase activity, protein kinase binding, protein phosphatase 2A binding, protein phosphatase binding, protein phosphatase inhibitor activity, protein phosphatase type 2A regulator activity Human PPOX Reactome UniProtKB {GO:0031966=PMID:7713909, GO:0042493=GO_REF:0000019, GO:0050660=PMID:7713909, GO:0044281=Reactome:REACT_111217, GO:0006782=GO_REF:0000041, GO:0006783=Reactome:REACT_9465, GO:0005758=Reactome:REACT_9418, GO:0004729=Reactome:REACT_9418, GO:0006778=Reactome:REACT_9431, GO:0006779=PMID:7713909, GO:0031304=GO_REF:0000024, GO:0016491=GO_REF:0000002, GO:0031305=GO_REF:0000019, GO:0055114=PMID:7713909} P50336 Protoporphyrinogen oxidase protein 20130213 {GO:0031966=IMP, GO:0042493=IEA, GO:0050660=TAS, GO:0044281=TAS, GO:0006782=IEA, GO:0006783=TAS, GO:0005758=TAS, GO:0004729=TAS, GO:0006778=TAS, GO:0006779=IDA, GO:0031304=ISS, GO:0016491=IEA, GO:0031305=IEA, GO:0055114=IDA} heme biosynthetic process, oxidation-reduction process, porphyrin-containing compound biosynthetic process, porphyrin-containing compound metabolic process, protoporphyrinogen IX biosynthetic process, response to drug, small molecule metabolic process integral to mitochondrial inner membrane, intrinsic to mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial membrane flavin adenine dinucleotide binding, oxidoreductase activity, oxygen-dependent protoporphyrinogen oxidase activity Human PPP1CA IntAct UniProtKB {GO:0005515=PMID:22321011, GO:0006629=Reactome:REACT_602, GO:0030324=GO_REF:0000019, GO:0005634=PMID:11739654, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_15496, GO:0005737=PMID:11739654, GO:0006470=GO_REF:0000019, GO:0043197=GO_REF:0000019, GO:0000164=GO_REF:0000019, GO:0043204=GO_REF:0000019, GO:0004721=GO_REF:0000003, GO:0007179=Reactome:REACT_120850, GO:0019433=Reactome:REACT_494, GO:0004722=GO_REF:0000019, GO:0030512=Reactome:REACT_120727, GO:0005979=GO_REF:0000019, GO:0005977=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0042587=GO_REF:0000019, GO:0007049=GO_REF:0000037, GO:0070688=PMID:19377461, GO:0043021=GO_REF:0000019, GO:0048754=GO_REF:0000019, GO:0072357=PMID:20516061, GO:0005981=GO_REF:0000019, GO:0051301=GO_REF:0000037} P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit protein 20130415 {GO:0005515=IPI, GO:0006629=TAS, GO:0030324=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0006470=IEA, GO:0043197=IEA, GO:0000164=IEA, GO:0043204=IEA, GO:0004721=IEA, GO:0007179=TAS, GO:0019433=TAS, GO:0004722=IEA, GO:0030512=TAS, GO:0005979=IEA, GO:0005977=IEA, GO:0005730=IEA, GO:0042587=IEA, GO:0007049=IEA, GO:0070688=IDA, GO:0043021=IEA, GO:0048754=IEA, GO:0072357=IDA, GO:0005981=IEA, GO:0051301=IEA} branching morphogenesis of an epithelial tube, cell cycle, cell division, glycogen metabolic process, lipid metabolic process, lung development, negative regulation of transforming growth factor beta receptor signaling pathway, protein dephosphorylation, regulation of glycogen biosynthetic process, regulation of glycogen catabolic process, small molecule metabolic process, transforming growth factor beta receptor signaling pathway, triglyceride catabolic process MLL5-L complex, PTW/PP1 phosphatase complex, cytoplasm, cytosol, dendritic spine, glycogen granule, nucleolus, nucleus, perikaryon, protein phosphatase type 1 complex metal ion binding, phosphoprotein phosphatase activity, protein binding, protein serine/threonine phosphatase activity, ribonucleoprotein complex binding Human UniProtKB:Q8TEC5 PPP1CB IntAct UniProtKB {GO:0005515=PMID:17511879, GO:0006629=Reactome:REACT_602, GO:0044281=Reactome:REACT_111217, GO:0030155=PMID:20354225, GO:0046872=GO_REF:0000037, GO:0006470=GO_REF:0000019, GO:0000164=GO_REF:0000019, GO:0000086=Reactome:REACT_2203, GO:0007179=Reactome:REACT_120850, GO:0004722=GO_REF:0000019, GO:0019433=Reactome:REACT_494, GO:0030512=Reactome:REACT_120727, GO:0017018=GO_REF:0000024, GO:0005979=GO_REF:0000019, GO:0019901=PMID:20354225, GO:0005977=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0050115=PMID:20354225, GO:0042587=GO_REF:0000019, GO:0016787=GO_REF:0000002, GO:0070688=PMID:19377461, GO:0005654=Reactome:REACT_160137, GO:0000278=Reactome:REACT_152, GO:0072357=PMID:20354225, GO:0051301=GO_REF:0000037, GO:0005981=GO_REF:0000019} P62140 Serine/threonine-protein phosphatase PP1-beta catalytic subunit protein 20130415 {GO:0005515=IPI, GO:0006629=TAS, GO:0044281=TAS, GO:0030155=IDA, GO:0046872=IEA, GO:0006470=IEA, GO:0000164=IEA, GO:0000086=TAS, GO:0007179=TAS, GO:0004722=IEA, GO:0019433=TAS, GO:0030512=TAS, GO:0017018=ISS, GO:0005979=IEA, GO:0019901=IPI, GO:0005977=IEA, GO:0005730=IEA, GO:0050115=IDA, GO:0042587=IEA, GO:0016787=IEA, GO:0070688=IDA, GO:0005654=TAS, GO:0000278=TAS, GO:0072357=IDA, GO:0051301=IEA, GO:0005981=IEA} G2/M transition of mitotic cell cycle, cell division, glycogen metabolic process, lipid metabolic process, mitotic cell cycle, negative regulation of transforming growth factor beta receptor signaling pathway, protein dephosphorylation, regulation of cell adhesion, regulation of glycogen biosynthetic process, regulation of glycogen catabolic process, small molecule metabolic process, transforming growth factor beta receptor signaling pathway, triglyceride catabolic process MLL5-L complex, PTW/PP1 phosphatase complex, glycogen granule, nucleolus, nucleoplasm, protein phosphatase type 1 complex hydrolase activity, metal ion binding, myosin phosphatase activity, myosin-light-chain-phosphatase activity, protein binding, protein kinase binding, protein serine/threonine phosphatase activity Human UniProtKB:P38398 PPP1CC IntAct UniProtKB {GO:0006629=Reactome:REACT_602, GO:0005515=PMID:21397856, GO:0000236=Reactome:REACT_682, GO:0005741=GO_REF:0000019, GO:0005634=PMID:11739654, GO:0044281=Reactome:REACT_111217, GO:0032154=GO_REF:0000039, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_150414, GO:0005739=PMID:17936702, GO:0005737=PMID:11739654, GO:0006470=GO_REF:0000019, GO:0000087=Reactome:REACT_910, GO:0007179=Reactome:REACT_120850, GO:0004721=Reactome:REACT_120899, GO:0019433=Reactome:REACT_494, GO:0004722=PMID:17936702, GO:0046822=GO_REF:0000019, GO:0030512=Reactome:REACT_120727, GO:0019901=PMID:10880350, GO:0005977=GO_REF:0000037, GO:0005730=PMID:11739654, GO:0030496=GO_REF:0000039, GO:0043234=PMID:10880350, GO:0016607=GO_REF:0000039, GO:0016787=GO_REF:0000002, GO:0070688=PMID:19377461, GO:0000777=GO_REF:0000039, GO:0000278=Reactome:REACT_152, GO:0072357=PMID:20516061, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit protein 20130415 {GO:0006629=TAS, GO:0005515=IPI, GO:0000236=TAS, GO:0005741=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0032154=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0005739=IDA, GO:0005737=IDA, GO:0006470=IEA, GO:0000087=TAS, GO:0007179=TAS, GO:0004721=TAS, GO:0019433=TAS, GO:0004722=IMP, GO:0046822=IEA, GO:0030512=TAS, GO:0019901=IPI, GO:0005977=IEA, GO:0005730=IDA, GO:0030496=IEA, GO:0043234=IMP, GO:0016607=IEA, GO:0016787=IEA, GO:0070688=IDA, GO:0000777=IEA, GO:0000278=TAS, GO:0072357=IDA, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, cell division, glycogen metabolic process, lipid metabolic process, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, negative regulation of transforming growth factor beta receptor signaling pathway, protein dephosphorylation, regulation of nucleocytoplasmic transport, small molecule metabolic process, transforming growth factor beta receptor signaling pathway, triglyceride catabolic process MLL5-L complex, PTW/PP1 phosphatase complex, cleavage furrow, condensed chromosome kinetochore, cytoplasm, cytosol, midbody, mitochondrial outer membrane, mitochondrion, nuclear speck, nucleolus, nucleus, protein complex hydrolase activity, metal ion binding, phosphoprotein phosphatase activity, protein binding, protein kinase binding, protein serine/threonine phosphatase activity Human UniProtKB:O94763 PPP1R10 PINC UniProtKB {GO:0004864=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0006606=PMID:9461602, GO:0000785=GO_REF:0000024, GO:0072357=GO_REF:0000024, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000002} Q96QC0 Serine/threonine-protein phosphatase 1 regulatory subunit 10 protein 20061106 {GO:0004864=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0006606=TAS, GO:0000785=ISS, GO:0072357=ISS, GO:0003677=IEA, GO:0006351=IEA} protein import into nucleus, transcription, DNA-dependent PTW/PP1 phosphatase complex, chromatin, nucleus DNA binding, RNA binding, protein phosphatase inhibitor activity, zinc ion binding Human PPP1R11 UniProtKB UniProtKB {GO:0005737=GO_REF:0000024, GO:0004864=GO_REF:0000037} O60927 Protein phosphatase 1 regulatory subunit 11 protein 20120802 {GO:0005737=ISS, GO:0004864=IEA} cytoplasm protein phosphatase inhibitor activity Human UniProtKB:Q8K1L5 PPP1R12A GOC UniProtKB {GO:0004857=PMID:19245366, GO:0005515=PMID:16417406, GO:0005813=PMID:18477460, GO:0035507=PMID:20354225, GO:0019901=PMID:18477460, GO:0043086=PMID:19245366, GO:0030155=PMID:20354225, GO:0051297=PMID:18477460, GO:0007165=PMID:8662509, GO:0071889=PMID:20354225, GO:0007067=PMID:18477460, GO:0006470=PMID:18477460, GO:0019208=PMID:18477460, GO:0043292=PMID:20634291, GO:0000086=Reactome:REACT_2203, GO:0045944=PMID:19245366, GO:0000776=PMID:18477460, GO:0005654=Reactome:REACT_160137, GO:0004871=PMID:8662509, GO:0000278=Reactome:REACT_152, GO:0046822=GO_REF:0000019, GO:0072357=PMID:20354225} O14974 Protein phosphatase 1 regulatory subunit 12A protein 20130413 {GO:0004857=IDA, GO:0005515=IPI, GO:0005813=IDA, GO:0035507=IDA, GO:0019901=IPI, GO:0043086=IDA, GO:0030155=IDA, GO:0051297=IMP, GO:0007165=NAS, GO:0071889=IDA, GO:0007067=IMP, GO:0006470=IMP, GO:0019208=IMP, GO:0043292=IDA, GO:0000086=TAS, GO:0045944=IDA, GO:0000776=IDA, GO:0005654=TAS, GO:0004871=NAS, GO:0000278=TAS, GO:0046822=IEA, GO:0072357=IDA} G2/M transition of mitotic cell cycle, centrosome organization, mitosis, mitotic cell cycle, negative regulation of catalytic activity, positive regulation of transcription from RNA polymerase II promoter, protein dephosphorylation, regulation of cell adhesion, regulation of myosin-light-chain-phosphatase activity, regulation of nucleocytoplasmic transport, signal transduction PTW/PP1 phosphatase complex, centrosome, contractile fiber, kinetochore, nucleoplasm 14-3-3 protein binding, enzyme inhibitor activity, phosphatase regulator activity, protein binding, protein kinase binding, signal transducer activity Human PPP1R12B GOC UniProtKB {GO:0007165=PMID:9570949, GO:0006937=PMID:9570949, GO:0005737=GO_REF:0000039, GO:0005886=GO_REF:0000052, GO:0000086=Reactome:REACT_2203, GO:0005654=Reactome:REACT_160137, GO:0043085=PMID:9570949, GO:0000278=Reactome:REACT_152, GO:0008047=PMID:9570949, GO:0015629=GO_REF:0000052} O60237 Protein phosphatase 1 regulatory subunit 12B protein 20130413 {GO:0007165=TAS, GO:0006937=TAS, GO:0005737=IEA, GO:0005886=IDA, GO:0000086=TAS, GO:0005654=TAS, GO:0043085=TAS, GO:0000278=TAS, GO:0008047=TAS, GO:0015629=IDA} G2/M transition of mitotic cell cycle, mitotic cell cycle, positive regulation of catalytic activity, regulation of muscle contraction, signal transduction actin cytoskeleton, cytoplasm, nucleoplasm, plasma membrane enzyme activator activity Human PPP1R12C IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0005737=GO_REF:0000039} Q9BZL4 Protein phosphatase 1 regulatory subunit 12C protein 20130415 {GO:0005515=IPI, GO:0005737=IEA} cytoplasm protein binding Human UniProtKB:P84022 PPP1R13B HPA UniProtKB {GO:0005515=PMID:14729977, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0006917=PMID:11684014, GO:0045786=PMID:14729977} Q96KQ4 Apoptosis-stimulating of p53 protein 1 protein 20101115 {GO:0005515=IPI, GO:0005737=IDA, GO:0005886=IDA, GO:0005730=IDA, GO:0006915=IEA, GO:0005634=IDA, GO:0006917=IDA, GO:0045786=TAS} apoptotic process, induction of apoptosis, negative regulation of cell cycle cytoplasm, nucleolus, nucleus, plasma membrane protein binding Human PPP1R13L IntAct UniProtKB {GO:0005515=PMID:17906639, GO:0003229=GO_REF:0000019, GO:0042633=GO_REF:0000019, GO:0003714=PMID:10336463, GO:0006915=GO_REF:0000037, GO:0003215=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0000122=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0060048=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0048871=GO_REF:0000019, GO:0031076=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0035264=GO_REF:0000019, GO:0008134=PMID:10336463} Q8WUF5 RelA-associated inhibitor protein 20130415 {GO:0005515=IPI, GO:0003229=IEA, GO:0042633=IEA, GO:0003714=TAS, GO:0006915=IEA, GO:0003215=IEA, GO:0005634=IEA, GO:0000122=IEA, GO:0009791=IEA, GO:0060048=IEA, GO:0006351=IEA, GO:0048871=IEA, GO:0031076=IEA, GO:0005737=IEA, GO:0035264=IEA, GO:0008134=TAS} apoptotic process, cardiac muscle contraction, cardiac right ventricle morphogenesis, embryonic camera-type eye development, hair cycle, multicellular organism growth, multicellular organismal homeostasis, negative regulation of transcription from RNA polymerase II promoter, post-embryonic development, transcription, DNA-dependent, ventricular cardiac muscle tissue development cytoplasm, nucleus protein binding, transcription corepressor activity, transcription factor binding Human UniProtKB:P04637 PPP1R14A UniProtKB UniProtKB {GO:0042325=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0004864=GO_REF:0000037} Q96A00 Protein phosphatase 1 regulatory subunit 14A protein 20130413 {GO:0042325=IEA, GO:0005737=IEA, GO:0004864=IEA} regulation of phosphorylation cytoplasm protein phosphatase inhibitor activity Human UniProtKB-SubCell:SL-0086 PPP1R14B UniProtKB UniProtKB {GO:0008599=GO_REF:0000019, GO:0042325=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0004864=GO_REF:0000037, GO:0019212=GO_REF:0000019} Q96C90 Protein phosphatase 1 regulatory subunit 14B protein 20130413 {GO:0008599=IEA, GO:0042325=IEA, GO:0005737=IEA, GO:0004864=IEA, GO:0019212=IEA} regulation of phosphorylation cytoplasm phosphatase inhibitor activity, protein phosphatase inhibitor activity, protein phosphatase type 1 regulator activity Human UniProtKB-SubCell:SL-0086 PPP1R14C UniProtKB UniProtKB {GO:0042325=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0016020=GO_REF:0000039, GO:0004865=GO_REF:0000019} Q8TAE6 Protein phosphatase 1 regulatory subunit 14C protein 20130413 {GO:0042325=IEA, GO:0005737=IEA, GO:0016020=IEA, GO:0004865=IEA} regulation of phosphorylation cytoplasm, membrane protein serine/threonine phosphatase inhibitor activity Human UniProtKB-SubCell:SL-0162 PPP1R15A IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0005783=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0007179=Reactome:REACT_120850, GO:0007050=PMID:9153226, GO:0030512=Reactome:REACT_120727, GO:0006974=PMID:9153226, GO:0006417=GO_REF:0000037, GO:0005829=Reactome:REACT_121180, GO:0030968=GO_REF:0000019} O75807 Protein phosphatase 1 regulatory subunit 15A protein 20130415 {GO:0005515=IPI, GO:0005783=IEA, GO:0006915=IEA, GO:0007179=TAS, GO:0007050=TAS, GO:0030512=TAS, GO:0006974=TAS, GO:0006417=IEA, GO:0005829=TAS, GO:0030968=IEA} apoptotic process, cell cycle arrest, endoplasmic reticulum unfolded protein response, negative regulation of transforming growth factor beta receptor signaling pathway, regulation of translation, response to DNA damage stimulus, transforming growth factor beta receptor signaling pathway cytosol, endoplasmic reticulum protein binding Human UniProtKB:P56545 PPP1R15B ENSEMBL UniProtKB {GO:0042542=GO_REF:0000019, GO:0006983=GO_REF:0000019, GO:0000164=GO_REF:0000019, GO:0004722=GO_REF:0000019, GO:0006417=GO_REF:0000037} Q5SWA1 Protein phosphatase 1 regulatory subunit 15B protein 20130413 {GO:0042542=IEA, GO:0006983=IEA, GO:0000164=IEA, GO:0004722=IEA, GO:0006417=IEA} ER overload response, regulation of translation, response to hydrogen peroxide protein phosphatase type 1 complex protein serine/threonine phosphatase activity Human Ensembl:ENSMUSP00000057062 PPP1R16A HPA UniProtKB {GO:0005515=PMID:19060904, GO:0005886=GO_REF:0000052} Q96I34 Protein phosphatase 1 regulatory subunit 16A protein 20100326 {GO:0005515=IPI, GO:0005886=IDA} plasma membrane protein binding Human PPP1R16B UniProtKB UniProtKB {GO:0005515=PMID:18586956, GO:0051489=GO_REF:0000024, GO:0007165=PMID:12055102, GO:0005886=PMID:18586956, GO:0019903=PMID:12055102, GO:0005634=PMID:18586956} Q96T49 Protein phosphatase 1 regulatory inhibitor subunit 16B protein 20101104 {GO:0005515=IPI, GO:0051489=ISS, GO:0007165=NAS, GO:0005886=IDA, GO:0019903=NAS, GO:0005634=IDA} regulation of filopodium assembly, signal transduction nucleus, plasma membrane protein binding, protein phosphatase binding Human UniProtKB:P26038 PPP1R17 PINC UniProtKB {GO:0007165=PMID:10051666, GO:0004864=PMID:10051666, GO:0004865=GO_REF:0000019, GO:0010921=GO_REF:0000024, GO:0007610=PMID:10051666, GO:0006468=PMID:10051666, GO:0005575=GO_REF:0000015, GO:0007417=PMID:10051666, GO:0007243=PMID:10051666} O96001 Protein phosphatase 1 regulatory subunit 17 protein 20030904 {GO:0007165=TAS, GO:0004864=TAS, GO:0004865=IEA, GO:0010921=ISS, GO:0007610=TAS, GO:0006468=TAS, GO:0005575=ND, GO:0007417=TAS, GO:0007243=TAS} behavior, central nervous system development, intracellular protein kinase cascade, protein phosphorylation, regulation of phosphatase activity, signal transduction cellular_component protein phosphatase inhibitor activity, protein serine/threonine phosphatase inhibitor activity Human PPP1R18 UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0019902=GO_REF:0000002, GO:0003779=GO_REF:0000037, GO:0005856=GO_REF:0000039} Q6NYC8 Phostensin protein 20130413 {GO:0005737=IEA, GO:0019902=IEA, GO:0003779=IEA, GO:0005856=IEA} cytoplasm, cytoskeleton actin binding, phosphatase binding Human UniProtKB-SubCell:SL-0090 PPP1R1A IntAct UniProtKB {GO:0005515=PMID:11564868, GO:0007165=GO_REF:0000002, GO:0004864=GO_REF:0000002, GO:0004865=PMID:8611507, GO:0005977=GO_REF:0000037} Q13522 Protein phosphatase 1 regulatory subunit 1A protein 20130415 {GO:0005515=IPI, GO:0007165=IEA, GO:0004864=IEA, GO:0004865=TAS, GO:0005977=IEA} glycogen metabolic process, signal transduction protein binding, protein phosphatase inhibitor activity, protein serine/threonine phosphatase inhibitor activity Human UniProtKB:O75807 PPP1R1B GOC UniProtKB {GO:0004864=PMID:10604473, GO:0005102=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0006351=GO_REF:0000019, GO:0005829=Reactome:REACT_15540, GO:0008599=Reactome:REACT_15496, GO:0035556=GO_REF:0000019, GO:0007165=PMID:10604473, GO:0001975=GO_REF:0000019, GO:0005737=GO_REF:0000029, GO:0008542=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0004860=PMID:10604473, GO:0006469=PMID:10604473, GO:0007621=GO_REF:0000019} Q9UD71 Protein phosphatase 1 regulatory subunit 1B protein 20130413 {GO:0004864=TAS, GO:0005102=IEA, GO:0005634=IEA, GO:0006351=IEA, GO:0005829=TAS, GO:0008599=TAS, GO:0035556=IEA, GO:0007165=TAS, GO:0001975=IEA, GO:0005737=NAS, GO:0008542=IEA, GO:0043025=IEA, GO:0004860=TAS, GO:0006469=TAS, GO:0007621=IEA} intracellular signal transduction, negative regulation of female receptivity, negative regulation of protein kinase activity, response to amphetamine, signal transduction, transcription, DNA-dependent, visual learning cytoplasm, cytosol, neuronal cell body, nucleus protein kinase inhibitor activity, protein phosphatase inhibitor activity, protein phosphatase type 1 regulator activity, receptor binding Human PPP1R2 IntAct UniProtKB {GO:0005515=PMID:12393858, GO:0004864=GO_REF:0000002, GO:0004865=PMID:8119416, GO:0005977=GO_REF:0000037, GO:0043666=GO_REF:0000002, GO:0006091=PMID:9126490, GO:0009966=GO_REF:0000002} P41236 Protein phosphatase inhibitor 2 protein 20130415 {GO:0005515=IPI, GO:0004864=IEA, GO:0004865=TAS, GO:0005977=IEA, GO:0043666=IEA, GO:0006091=TAS, GO:0009966=IEA} generation of precursor metabolites and energy, glycogen metabolic process, regulation of phosphoprotein phosphatase activity, regulation of signal transduction protein binding, protein phosphatase inhibitor activity, protein serine/threonine phosphatase inhibitor activity Human UniProtKB:Q8IWU2 PPP1R21 UniProtKB UniProtKB {GO:0019902=PMID:19389623} Q6ZMI0 Protein phosphatase 1 regulatory subunit 21 protein 20111103 {GO:0019902=IDA} phosphatase binding Human PPP1R26 HPA UniProtKB {GO:0019902=PMID:19389623, GO:0010923=PMID:19389623, GO:0004864=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q5T8A7 Protein phosphatase 1 regulatory subunit 26 protein 20120912 {GO:0019902=IDA, GO:0010923=IDA, GO:0004864=IEA, GO:0005730=IDA, GO:0005634=IDA} negative regulation of phosphatase activity nucleolus, nucleus phosphatase binding, protein phosphatase inhibitor activity NOT Human PPP1R27 IntAct UniProtKB {GO:0005515=PMID:19389623, GO:0019902=PMID:19389623, GO:0010923=PMID:19389623, GO:0004864=GO_REF:0000037} Q86WC6 Protein phosphatase 1 regulatory subunit 27 protein 20130415 {GO:0005515=IPI, GO:0019902=IDA, GO:0010923=IDA, GO:0004864=IEA} negative regulation of phosphatase activity phosphatase binding, protein binding, protein phosphatase inhibitor activity Human UniProtKB:P62136 PPP1R32 IntAct UniProtKB {GO:0005515=PMID:21382349, GO:0019902=PMID:19389623} Q7Z5V6 Protein phosphatase 1 regulatory subunit 32 protein 20130415 {GO:0005515=IPI, GO:0019902=IDA} phosphatase binding, protein binding Human UniProtKB:P36873-2 PPP1R35 UniProtKB UniProtKB {GO:0019902=PMID:19389623, GO:0010923=PMID:19389623, GO:0004864=GO_REF:0000037} Q8TAP8 Protein phosphatase 1 regulatory subunit 35 protein 20111103 {GO:0019902=IDA, GO:0010923=IDA, GO:0004864=IEA} negative regulation of phosphatase activity phosphatase binding, protein phosphatase inhibitor activity Human PPP1R36 UniProtKB UniProtKB {GO:0019902=PMID:19389623, GO:0004864=GO_REF:0000037, GO:0010923=PMID:19389623} Q96LQ0 Protein phosphatase 1 regulatory subunit 36 protein 20111103 {GO:0019902=IDA, GO:0004864=IEA, GO:0010923=IDA} negative regulation of phosphatase activity phosphatase binding, protein phosphatase inhibitor activity Human PPP1R37 UniProtKB UniProtKB {GO:0019902=PMID:19389623, GO:0010923=PMID:19389623, GO:0004864=GO_REF:0000037} O75864 Protein phosphatase 1 regulatory subunit 37 protein 20111103 {GO:0019902=IDA, GO:0010923=IDA, GO:0004864=IEA} negative regulation of phosphatase activity phosphatase binding, protein phosphatase inhibitor activity Human PPP1R3A UniProtKB UniProtKB {GO:0005977=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q16821 Protein phosphatase 1 regulatory subunit 3A protein 20130413 {GO:0005977=IEA, GO:0016021=IEA} glycogen metabolic process integral to membrane Human UniProtKB-KW:KW-0812 PPP1R3B ENSEMBL UniProtKB {GO:0042587=GO_REF:0000019, GO:0005979=GO_REF:0000019, GO:0019888=GO_REF:0000019, GO:0000164=GO_REF:0000019, GO:0005977=GO_REF:0000037, GO:0019899=GO_REF:0000019, GO:0043231=GO_REF:0000019, GO:0005981=GO_REF:0000019} Q86XI6 Protein phosphatase 1 regulatory subunit 3B protein 20130413 {GO:0042587=IEA, GO:0005979=IEA, GO:0019888=IEA, GO:0000164=IEA, GO:0005977=IEA, GO:0019899=IEA, GO:0043231=IEA, GO:0005981=IEA} glycogen metabolic process, regulation of glycogen biosynthetic process, regulation of glycogen catabolic process glycogen granule, intracellular membrane-bounded organelle, protein phosphatase type 1 complex enzyme binding, protein phosphatase regulator activity Human Ensembl:ENSRNOP00000042713 PPP1R3C PINC UniProtKB {GO:0005515=PMID:18070875, GO:0019903=GO_REF:0000019, GO:0005978=GO_REF:0000019, GO:0004722=PMID:8985175} Q9UQK1 Protein phosphatase 1 regulatory subunit 3C protein 20070906 {GO:0005515=IPI, GO:0019903=IEA, GO:0005978=IEA, GO:0004722=TAS} glycogen biosynthetic process protein binding, protein phosphatase binding, protein serine/threonine phosphatase activity Human PPP1R3D PINC UniProtKB {GO:0042587=GO_REF:0000019, GO:0005979=GO_REF:0000019, GO:0005977=GO_REF:0000037, GO:0004722=PMID:9414128, GO:0019899=GO_REF:0000019, GO:0043231=GO_REF:0000019, GO:0005981=GO_REF:0000019} O95685 Protein phosphatase 1 regulatory subunit 3D protein 20030904 {GO:0042587=IEA, GO:0005979=IEA, GO:0005977=IEA, GO:0004722=TAS, GO:0019899=IEA, GO:0043231=IEA, GO:0005981=IEA} glycogen metabolic process, regulation of glycogen biosynthetic process, regulation of glycogen catabolic process glycogen granule, intracellular membrane-bounded organelle enzyme binding, protein serine/threonine phosphatase activity Human PPP1R3E UniProtKB UniProtKB {GO:0005977=GO_REF:0000037} Q9H7J1 Protein phosphatase 1 regulatory subunit 3E protein 20130413 {GO:0005977=IEA} glycogen metabolic process Human UniProtKB-KW:KW-0321 PPP1R3G ENSEMBL UniProtKB {GO:2000467=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0045725=GO_REF:0000019, GO:2001069=GO_REF:0000019, GO:0019903=GO_REF:0000019, GO:0042593=GO_REF:0000019} B7ZBB8 Protein phosphatase 1 regulatory subunit 3G protein 20130413 {GO:2000467=IEA, GO:0005737=IEA, GO:0045725=IEA, GO:2001069=IEA, GO:0019903=IEA, GO:0042593=IEA} glucose homeostasis, positive regulation of glycogen (starch) synthase activity, positive regulation of glycogen biosynthetic process cytoplasm glycogen binding, protein phosphatase binding Human Ensembl:ENSMUSP00000122712 PPP1R42 UniProtKB UniProtKB {GO:0005813=GO_REF:0000024, GO:0005737=GO_REF:0000037, GO:0045502=GO_REF:0000024, GO:0005815=GO_REF:0000024, GO:0015631=GO_REF:0000024, GO:0002177=GO_REF:0000024, GO:0015630=GO_REF:0000024, GO:0010921=GO_REF:0000019, GO:0003779=GO_REF:0000024} Q7Z4L9 Protein phosphatase 1 regulatory subunit 42 protein 20111102 {GO:0005813=ISS, GO:0005737=IEA, GO:0045502=ISS, GO:0005815=ISS, GO:0015631=ISS, GO:0002177=ISS, GO:0015630=ISS, GO:0010921=IEA, GO:0003779=ISS} regulation of phosphatase activity centrosome, cytoplasm, manchette, microtubule cytoskeleton, microtubule organizing center actin binding, dynein binding, tubulin binding Human UniProtKB:Q8R1Z4 PPP1R7 GOC UniProtKB {GO:0008599=PMID:7498485, GO:0008150=GO_REF:0000015, GO:0050790=PMID:10231361, GO:0005737=PMID:7498485, GO:0030234=PMID:10231361, GO:0005634=GO_REF:0000039} Q15435 Protein phosphatase 1 regulatory subunit 7 protein 20130413 {GO:0008599=TAS, GO:0008150=ND, GO:0050790=NAS, GO:0005737=TAS, GO:0030234=NAS, GO:0005634=IEA} biological_process, regulation of catalytic activity cytoplasm, nucleus enzyme regulator activity, protein phosphatase type 1 regulator activity Human PPP1R8 HPA UniProtKB {GO:0006397=GO_REF:0000037, GO:0008380=GO_REF:0000037, GO:0005515=PMID:11739654, GO:0006355=GO_REF:0000037, GO:0008283=GO_REF:0000019, GO:0003723=GO_REF:0000037, GO:0004865=PMID:7499293, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0006401=PMID:9153239, GO:0008599=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0004519=GO_REF:0000037, GO:0016607=PMID:11739654, GO:0005681=GO_REF:0000037, GO:0008995=PMID:9153239} Q12972 Nuclear inhibitor of protein phosphatase 1 protein 20100326 {GO:0006397=IEA, GO:0008380=IEA, GO:0005515=IPI, GO:0006355=IEA, GO:0008283=IEA, GO:0003723=IEA, GO:0004865=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA, GO:0006401=TAS, GO:0008599=IEA, GO:0005737=IEA, GO:0004519=IEA, GO:0016607=IDA, GO:0005681=IEA, GO:0008995=TAS} RNA catabolic process, RNA splicing, cell proliferation, mRNA processing, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nuclear speck, nucleolus, nucleus, spliceosomal complex DNA binding, RNA binding, endonuclease activity, protein binding, protein phosphatase type 1 regulator activity, protein serine/threonine phosphatase inhibitor activity, ribonuclease E activity NOT Human PPP1R9A UniProtKB UniProtKB {GO:0043005=GO_REF:0000039, GO:0019722=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0045202=GO_REF:0000037, GO:0003779=GO_REF:0000037, GO:0030175=GO_REF:0000019, GO:0031175=GO_REF:0000019, GO:0030154=GO_REF:0000037, GO:0030426=GO_REF:0000019, GO:0007399=GO_REF:0000037, GO:0005737=GO_REF:0000037, GO:0043197=GO_REF:0000019, GO:0007015=GO_REF:0000019, GO:0030864=GO_REF:0000019, GO:0005856=GO_REF:0000039} Q9ULJ8 Neurabin-1 protein 20130413 {GO:0043005=IEA, GO:0019722=IEA, GO:0030054=IEA, GO:0045202=IEA, GO:0003779=IEA, GO:0030175=IEA, GO:0031175=IEA, GO:0030154=IEA, GO:0030426=IEA, GO:0007399=IEA, GO:0005737=IEA, GO:0043197=IEA, GO:0007015=IEA, GO:0030864=IEA, GO:0005856=IEA} actin filament organization, calcium-mediated signaling, cell differentiation, nervous system development, neuron projection development cell junction, cortical actin cytoskeleton, cytoplasm, cytoskeleton, dendritic spine, filopodium, growth cone, neuron projection, synapse actin binding Human UniProtKB-SubCell:SL-0261 PPP1R9B UniProtKB UniProtKB {GO:0008380=PMID:11278317, GO:0005515=PMID:19151759, GO:0030308=PMID:11278317, GO:0005886=PMID:19151759, GO:0004864=PMID:11278317, GO:0007096=PMID:11278317, GO:0045202=GO_REF:0000039, GO:0030175=PMID:19151759, GO:0030154=GO_REF:0000037, GO:0005737=PMID:19151759, GO:0043197=GO_REF:0000039, GO:0005912=GO_REF:0000039, GO:0001560=PMID:11278317, GO:0000164=PMID:11278317, GO:0042127=PMID:11278317, GO:0007050=PMID:11278317, GO:0046847=PMID:19151759, GO:0005856=GO_REF:0000039, GO:0003779=GO_REF:0000037, GO:0032587=PMID:19151759, GO:0071315=GO_REF:0000024, GO:0030027=PMID:19151759, GO:0007399=GO_REF:0000037, GO:0016477=PMID:19151759, GO:0008157=PMID:11278317, GO:0005654=PMID:11278317, GO:2000474=GO_REF:0000024} Q96SB3 Neurabin-2 protein 20110317 {GO:0008380=NAS, GO:0005515=IPI, GO:0030308=IDA, GO:0005886=IDA, GO:0004864=NAS, GO:0007096=NAS, GO:0045202=IEA, GO:0030175=IDA, GO:0030154=IEA, GO:0005737=IDA, GO:0043197=IEA, GO:0005912=IEA, GO:0001560=TAS, GO:0000164=TAS, GO:0042127=NAS, GO:0007050=TAS, GO:0046847=IMP, GO:0005856=IEA, GO:0003779=IEA, GO:0032587=IDA, GO:0071315=ISS, GO:0030027=IDA, GO:0007399=IEA, GO:0016477=IMP, GO:0008157=NAS, GO:0005654=IMP, GO:2000474=ISS} RNA splicing, cell cycle arrest, cell differentiation, cell migration, cellular response to morphine, filopodium assembly, negative regulation of cell growth, nervous system development, regulation of cell growth by extracellular stimulus, regulation of cell proliferation, regulation of exit from mitosis, regulation of opioid receptor signaling pathway adherens junction, cytoplasm, cytoskeleton, dendritic spine, filopodium, lamellipodium, nucleoplasm, plasma membrane, protein phosphatase type 1 complex, ruffle membrane, synapse actin binding, protein binding, protein phosphatase 1 binding, protein phosphatase inhibitor activity Human PPP2CA BHF-UCL UniProtKB {GO:0005515=PMID:19156129, GO:0008380=PMID:11007961, GO:0010467=Reactome:REACT_71, GO:0030308=PMID:11007961, GO:0010469=GO_REF:0000019, GO:0071902=PMID:20080667, GO:0030111=PMID:11007961, GO:0005886=GO_REF:0000019, GO:0006672=PMID:11007961, GO:0000159=PMID:17055435, GO:0005634=PMID:11007961, GO:0010719=PMID:20080667, GO:0030155=PMID:11007961, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_160246, GO:0005739=PMID:11007961, GO:0070208=GO_REF:0000019, GO:0000188=PMID:11007961, GO:0031952=GO_REF:0000019, GO:0006470=PMID:2849764, GO:0000184=Reactome:REACT_75886, GO:0000087=Reactome:REACT_910, GO:0015630=PMID:11007961, GO:0046983=GO_REF:0000019, GO:0004721=GO_REF:0000003, GO:0004722=GO_REF:0000019, GO:0006275=PMID:11007961, GO:0042518=PMID:11007961, GO:0006355=PMID:11007961, GO:0010033=PMID:11007961, GO:0016070=Reactome:REACT_21257, GO:0042176=GO_REF:0000019, GO:0016071=Reactome:REACT_20605, GO:0007084=Reactome:REACT_160113, GO:0006917=PMID:11007961, GO:0008022=GO_REF:0000019, GO:0000922=GO_REF:0000039, GO:0007126=GO_REF:0000037, GO:0016020=PMID:11007961, GO:0008543=Reactome:REACT_9470, GO:0019932=PMID:11007961, GO:0045595=PMID:11360189, GO:0007498=GO_REF:0000019, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0040008=PMID:11360189, GO:0000775=GO_REF:0000039} P67775 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform protein 20101119 {GO:0005515=IPI, GO:0008380=NAS, GO:0010467=TAS, GO:0030308=NAS, GO:0010469=IEA, GO:0071902=IMP, GO:0030111=NAS, GO:0005886=IEA, GO:0006672=NAS, GO:0000159=IDA, GO:0005634=NAS, GO:0010719=IMP, GO:0030155=NAS, GO:0046872=IEA, GO:0005829=TAS, GO:0005739=NAS, GO:0070208=IEA, GO:0000188=NAS, GO:0031952=IEA, GO:0006470=TAS, GO:0000184=TAS, GO:0000087=TAS, GO:0015630=NAS, GO:0046983=IEA, GO:0004721=IEA, GO:0004722=IEA, GO:0006275=NAS, GO:0042518=NAS, GO:0006355=NAS, GO:0010033=NAS, GO:0016070=TAS, GO:0042176=IEA, GO:0016071=TAS, GO:0007084=TAS, GO:0006917=TAS, GO:0008022=IEA, GO:0000922=IEA, GO:0007126=IEA, GO:0016020=NAS, GO:0008543=TAS, GO:0019932=NAS, GO:0045595=NAS, GO:0007498=IEA, GO:0000278=TAS, GO:0000090=TAS, GO:0040008=NAS, GO:0000775=IEA} M phase of mitotic cell cycle, RNA metabolic process, RNA splicing, ceramide metabolic process, fibroblast growth factor receptor signaling pathway, gene expression, inactivation of MAPK activity, induction of apoptosis, mRNA metabolic process, meiosis, mesoderm development, mitotic anaphase, mitotic cell cycle, mitotic nuclear envelope reassembly, negative regulation of cell growth, negative regulation of epithelial to mesenchymal transition, negative regulation of tyrosine phosphorylation of Stat3 protein, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, positive regulation of protein serine/threonine kinase activity, protein dephosphorylation, protein heterotrimerization, regulation of DNA replication, regulation of Wnt receptor signaling pathway, regulation of cell adhesion, regulation of cell differentiation, regulation of growth, regulation of protein autophosphorylation, regulation of protein catabolic process, regulation of receptor activity, regulation of transcription, DNA-dependent, response to organic substance, second-messenger-mediated signaling chromosome, centromeric region, cytosol, membrane, microtubule cytoskeleton, mitochondrion, nucleus, plasma membrane, protein phosphatase type 2A complex, spindle pole metal ion binding, phosphoprotein phosphatase activity, protein C-terminus binding, protein binding, protein dimerization activity, protein serine/threonine phosphatase activity Human PPP2CB IntAct UniProtKB {GO:0005515=PMID:19156129, GO:0010468=GO_REF:0000019, GO:0042542=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0000159=PMID:8206937, GO:0005634=GO_REF:0000039, GO:0008022=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_111241, GO:0046580=GO_REF:0000019, GO:0000922=GO_REF:0000039, GO:0005737=GO_REF:0000019, GO:0006470=PMID:2849765, GO:0016787=GO_REF:0000002, GO:0008543=Reactome:REACT_9470, GO:0043161=GO_REF:0000019, GO:0004721=GO_REF:0000003, GO:0004722=PMID:8206937, GO:0000775=GO_REF:0000039, GO:0046677=GO_REF:0000019} P62714 Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform protein 20130415 {GO:0005515=IPI, GO:0010468=IEA, GO:0042542=IEA, GO:0043066=IEA, GO:0000159=TAS, GO:0005634=IEA, GO:0008022=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0046580=IEA, GO:0000922=IEA, GO:0005737=IEA, GO:0006470=TAS, GO:0016787=IEA, GO:0008543=TAS, GO:0043161=IEA, GO:0004721=IEA, GO:0004722=TAS, GO:0000775=IEA, GO:0046677=IEA} fibroblast growth factor receptor signaling pathway, negative regulation of Ras protein signal transduction, negative regulation of apoptotic process, proteasomal ubiquitin-dependent protein catabolic process, protein dephosphorylation, regulation of gene expression, response to antibiotic, response to hydrogen peroxide chromosome, centromeric region, cytoplasm, cytosol, nucleus, protein phosphatase type 2A complex, spindle pole hydrolase activity, metal ion binding, phosphoprotein phosphatase activity, protein C-terminus binding, protein binding, protein serine/threonine phosphatase activity Human UniProtKB:P78318 PPP2R1A IntAct UniProtKB {GO:0005515=PMID:21075311, GO:0008380=PMID:11007961, GO:0010467=Reactome:REACT_71, GO:0030308=PMID:11007961, GO:0030111=PMID:11007961, GO:0008601=PMID:11007961, GO:0006672=PMID:11007961, GO:0000159=PMID:17055435, GO:0005634=PMID:11007961, GO:0003823=PMID:9847399, GO:0030155=PMID:11007961, GO:0005829=Reactome:REACT_160246, GO:0005739=PMID:11007961, GO:0000188=PMID:11007961, GO:0007059=PMID:16580887, GO:0006470=PMID:11007961, GO:0000184=Reactome:REACT_75886, GO:0000086=Reactome:REACT_2203, GO:0000087=Reactome:REACT_910, GO:0015630=PMID:11007961, GO:0004722=GO_REF:0000019, GO:0006275=PMID:11007961, GO:0042518=PMID:11007961, GO:0006355=PMID:11007961, GO:0010033=PMID:11007961, GO:0016070=Reactome:REACT_21257, GO:0046982=PMID:9847399, GO:0016071=Reactome:REACT_20605, GO:0007084=Reactome:REACT_160113, GO:0070262=GO_REF:0000019, GO:0042981=GO_REF:0000019, GO:0006917=PMID:11007961, GO:0006461=PMID:9989501, GO:0016020=PMID:11007961, GO:0008543=Reactome:REACT_9470, GO:0019932=PMID:11007961, GO:0045595=PMID:11360189, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0000775=PMID:16580887, GO:0040008=PMID:11360189} P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform protein 20130415 {GO:0005515=IPI, GO:0008380=NAS, GO:0010467=TAS, GO:0030308=NAS, GO:0030111=NAS, GO:0008601=TAS, GO:0006672=NAS, GO:0000159=IDA, GO:0005634=NAS, GO:0003823=IPI, GO:0030155=NAS, GO:0005829=TAS, GO:0005739=NAS, GO:0000188=NAS, GO:0007059=IDA, GO:0006470=TAS, GO:0000184=TAS, GO:0000086=TAS, GO:0000087=TAS, GO:0015630=NAS, GO:0004722=IEA, GO:0006275=NAS, GO:0042518=NAS, GO:0006355=NAS, GO:0010033=NAS, GO:0016070=TAS, GO:0046982=IPI, GO:0016071=TAS, GO:0007084=TAS, GO:0070262=IEA, GO:0042981=IEA, GO:0006917=TAS, GO:0006461=TAS, GO:0016020=NAS, GO:0008543=TAS, GO:0019932=NAS, GO:0045595=NAS, GO:0000278=TAS, GO:0000090=TAS, GO:0000775=IDA, GO:0040008=NAS} G2/M transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, RNA splicing, ceramide metabolic process, chromosome segregation, fibroblast growth factor receptor signaling pathway, gene expression, inactivation of MAPK activity, induction of apoptosis, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, mitotic nuclear envelope reassembly, negative regulation of cell growth, negative regulation of tyrosine phosphorylation of Stat3 protein, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, peptidyl-serine dephosphorylation, protein complex assembly, protein dephosphorylation, regulation of DNA replication, regulation of Wnt receptor signaling pathway, regulation of apoptotic process, regulation of cell adhesion, regulation of cell differentiation, regulation of growth, regulation of transcription, DNA-dependent, response to organic substance, second-messenger-mediated signaling chromosome, centromeric region, cytosol, membrane, microtubule cytoskeleton, mitochondrion, nucleus, protein phosphatase type 2A complex antigen binding, protein binding, protein heterodimerization activity, protein phosphatase type 2A regulator activity, protein serine/threonine phosphatase activity Human UniProtKB:Q00005 PPP2R1B IntAct UniProtKB {GO:0005515=PMID:21172653} P30154 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:O08722 PPP2R2A IntAct UniProtKB {GO:0005515=PMID:17540176, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0008601=PMID:1849734, GO:0007084=Reactome:REACT_160113, GO:0000159=PMID:17245430, GO:0043278=GO_REF:0000019, GO:0005829=Reactome:REACT_160246, GO:0007165=GO_REF:0000002, GO:0006470=PMID:1849734, GO:0000184=Reactome:REACT_75886, GO:0000087=Reactome:REACT_910, GO:0004722=PMID:1849734, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} P63151 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0008601=TAS, GO:0007084=TAS, GO:0000159=IDA, GO:0043278=IEA, GO:0005829=TAS, GO:0007165=IEA, GO:0006470=IDA, GO:0000184=TAS, GO:0000087=TAS, GO:0004722=IDA, GO:0000278=TAS, GO:0000090=TAS} M phase of mitotic cell cycle, RNA metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, mitotic nuclear envelope reassembly, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, protein dephosphorylation, response to morphine, signal transduction cytosol, protein phosphatase type 2A complex protein binding, protein phosphatase type 2A regulator activity, protein serine/threonine phosphatase activity Human UniProtKB:P30154 PPP2R2B IntAct UniProtKB {GO:0005515=PMID:21075311, GO:0008601=GO_REF:0000002, GO:0006626=GO_REF:0000019, GO:0007286=GO_REF:0000019, GO:0000159=GO_REF:0000019, GO:0005741=GO_REF:0000024, GO:0033554=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0043653=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0034047=GO_REF:0000019, GO:0005739=GO_REF:0000024, GO:0007165=GO_REF:0000002, GO:0043525=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0030182=GO_REF:0000019, GO:0005856=GO_REF:0000039} Q00005 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform protein 20130415 {GO:0005515=IPI, GO:0008601=IEA, GO:0006626=IEA, GO:0007286=IEA, GO:0000159=IEA, GO:0005741=ISS, GO:0033554=IEA, GO:0032403=IEA, GO:0043653=IEA, GO:0005829=IEA, GO:0034047=IEA, GO:0005739=ISS, GO:0007165=IEA, GO:0043525=IEA, GO:0007420=IEA, GO:0030182=IEA, GO:0005856=IEA} brain development, cellular response to stress, mitochondrial fragmentation involved in apoptotic process, neuron differentiation, positive regulation of neuron apoptotic process, protein targeting to mitochondrion, regulation of protein phosphatase type 2A activity, signal transduction, spermatid development cytoskeleton, cytosol, mitochondrial outer membrane, mitochondrion, protein phosphatase type 2A complex protein binding, protein complex binding, protein phosphatase type 2A regulator activity Human UniProtKB:P30153 PPP2R2C UniProtKB UniProtKB {GO:0007165=GO_REF:0000029, GO:0008601=PMID:10945473, GO:0000159=PMID:10945473} Q9Y2T4 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform protein 20021104 {GO:0007165=NAS, GO:0008601=NAS, GO:0000159=NAS} signal transduction protein phosphatase type 2A complex protein phosphatase type 2A regulator activity Human PPP2R2D Reactome UniProtKB {GO:0010458=GO_REF:0000024, GO:0007165=GO_REF:0000002, GO:0007067=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0000088=Reactome:REACT_765, GO:0008601=GO_REF:0000024, GO:0000087=Reactome:REACT_910, GO:0000159=GO_REF:0000024, GO:0000278=Reactome:REACT_152, GO:0051301=GO_REF:0000037} Q66LE6 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform protein 20120306 {GO:0010458=ISS, GO:0007165=IEA, GO:0007067=ISS, GO:0005737=IEA, GO:0000088=TAS, GO:0008601=ISS, GO:0000087=TAS, GO:0000159=ISS, GO:0000278=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, cell division, exit from mitosis, mitosis, mitotic cell cycle, mitotic prophase, signal transduction cytoplasm, protein phosphatase type 2A complex protein phosphatase type 2A regulator activity Human PPP2R3A BHF-UCL UniProtKB {GO:0005515=PMID:9847399, GO:0061053=PMID:16567647, GO:0006470=PMID:1849734, GO:0008601=PMID:8392071, GO:0005509=GO_REF:0000002, GO:0000159=PMID:17055435} Q06190 Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha protein 20120807 {GO:0005515=IPI, GO:0061053=ISS, GO:0006470=ISS, GO:0008601=TAS, GO:0005509=IEA, GO:0000159=IDA} protein dephosphorylation, somite development protein phosphatase type 2A complex calcium ion binding, protein binding, protein phosphatase type 2A regulator activity Human UniProtKB:F6T226 PPP2R3B Reactome UniProtKB {GO:0005515=PMID:9847399, GO:0000082=Reactome:REACT_1783, GO:0006470=GO_REF:0000024, GO:0008601=PMID:10629059, GO:0005509=GO_REF:0000002, GO:0000159=GO_REF:0000024, GO:0005654=Reactome:REACT_421, GO:0004721=Reactome:REACT_421, GO:0005634=PMID:10629059, GO:0007050=PMID:10629059, GO:0004722=GO_REF:0000024, GO:0000278=Reactome:REACT_152} Q9Y5P8 Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta protein 20130204 {GO:0005515=IPI, GO:0000082=TAS, GO:0006470=ISS, GO:0008601=TAS, GO:0005509=IEA, GO:0000159=ISS, GO:0005654=TAS, GO:0004721=TAS, GO:0005634=TAS, GO:0007050=TAS, GO:0004722=ISS, GO:0000278=TAS} G1/S transition of mitotic cell cycle, cell cycle arrest, mitotic cell cycle, protein dephosphorylation nucleoplasm, nucleus, protein phosphatase type 2A complex calcium ion binding, phosphoprotein phosphatase activity, protein binding, protein phosphatase type 2A regulator activity, protein serine/threonine phosphatase activity Human PPP2R3C UniProtKB UniProtKB {GO:0005813=PMID:21399614, GO:0005737=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0005634=GO_REF:0000039} Q969Q6 Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma protein 20110517 {GO:0005813=IDA, GO:0005737=IEA, GO:0005509=IEA, GO:0005634=IEA} centrosome, cytoplasm, nucleus calcium ion binding Human PPP2R4 InterPro UniProtKB {GO:0000413=GO_REF:0000033, GO:0006200=PMID:16916641, GO:0008601=PMID:16916641, GO:0000159=PMID:10318862, GO:0005634=GO_REF:0000052, GO:0042803=PMID:16916641, GO:0008160=PMID:16916641, GO:0005737=PMID:17333320, GO:0006457=GO_REF:0000037, GO:0016887=PMID:16916641, GO:0051721=PMID:16916641, GO:0043065=PMID:17333320, GO:0046982=PMID:10318862, GO:0035307=PMID:16916641, GO:0035308=PMID:16916641, GO:0003755=GO_REF:0000033, GO:0005730=GO_REF:0000052, GO:0005102=PMID:10830164, GO:0019211=GO_REF:0000002, GO:0034704=PMID:10830164, GO:0005524=PMID:16916641, GO:0030472=GO_REF:0000033, GO:0032516=PMID:16916641, GO:0032515=PMID:16916641, GO:0043666=PMID:16916641} Q5T949 Serine/threonine-protein phosphatase 2A activator protein 20130413 {GO:0000413=IBA, GO:0006200=IDA, GO:0008601=IDA, GO:0000159=TAS, GO:0005634=IDA, GO:0042803=IDA, GO:0008160=IDA, GO:0005737=IDA, GO:0006457=IEA, GO:0016887=IDA, GO:0051721=IDA, GO:0043065=IDA, GO:0046982=TAS, GO:0035307=IDA, GO:0035308=IDA, GO:0003755=IBA, GO:0005730=IDA, GO:0005102=IPI, GO:0019211=IEA, GO:0034704=IDA, GO:0005524=IDA, GO:0030472=IBA, GO:0032516=IDA, GO:0032515=IDA, GO:0043666=IDA} ATP catabolic process, mitotic spindle organization in nucleus, negative regulation of phosphoprotein phosphatase activity, negative regulation of protein dephosphorylation, positive regulation of apoptotic process, positive regulation of phosphoprotein phosphatase activity, positive regulation of protein dephosphorylation, protein folding, protein peptidyl-prolyl isomerization, regulation of phosphoprotein phosphatase activity calcium channel complex, cytoplasm, nucleolus, nucleus, protein phosphatase type 2A complex ATP binding, ATPase activity, peptidyl-prolyl cis-trans isomerase activity, phosphatase activator activity, protein heterodimerization activity, protein homodimerization activity, protein phosphatase 2A binding, protein phosphatase type 2A regulator activity, protein tyrosine phosphatase activator activity, receptor binding Human InterPro:IPR004327 PPP2R5A BHF-UCL UniProtKB {GO:0005515=PMID:18782753, GO:0030018=GO_REF:0000019, GO:0008601=GO_REF:0000002, GO:0035307=PMID:21075214, GO:0090219=PMID:21075214, GO:0000159=PMID:17245430, GO:0005634=GO_REF:0000039, GO:0031430=PMID:18782775, GO:0007165=GO_REF:0000002, GO:0005737=PMID:21075214, GO:0016020=PMID:15569306, GO:0090005=PMID:21075214, GO:0019900=PMID:21075214, GO:0000775=GO_REF:0000039} Q15172 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform protein 20110301 {GO:0005515=IPI, GO:0030018=IEA, GO:0008601=IEA, GO:0035307=IMP, GO:0090219=IMP, GO:0000159=IDA, GO:0005634=IEA, GO:0031430=ISS, GO:0007165=IEA, GO:0005737=IDA, GO:0016020=IDA, GO:0090005=IMP, GO:0019900=IPI, GO:0000775=IEA} negative regulation of establishment of protein localization to plasma membrane, negative regulation of lipid kinase activity, positive regulation of protein dephosphorylation, signal transduction M band, Z disc, chromosome, centromeric region, cytoplasm, membrane, nucleus, protein phosphatase type 2A complex kinase binding, protein binding, protein phosphatase type 2A regulator activity Human PPP2R5B IntAct UniProtKB {GO:0005515=PMID:15380617, GO:0007165=GO_REF:0000002, GO:0005737=PMID:8703017, GO:0008601=GO_REF:0000002, GO:0000159=GO_REF:0000002, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0030968=Reactome:REACT_18356, GO:0005829=Reactome:REACT_115580} Q15173 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform protein 20130415 {GO:0005515=IPI, GO:0007165=IEA, GO:0005737=TAS, GO:0008601=IEA, GO:0000159=IEA, GO:0006987=TAS, GO:0044267=TAS, GO:0030968=TAS, GO:0005829=TAS} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, signal transduction cytoplasm, cytosol, protein phosphatase type 2A complex protein binding, protein phosphatase type 2A regulator activity Human UniProtKB:O96017 PPP2R5C MGI UniProtKB {GO:0005515=PMID:16580887, GO:0007165=GO_REF:0000002, GO:0008285=PMID:17245430, GO:0016485=PMID:12297508, GO:0008601=GO_REF:0000002, GO:0000159=GO_REF:0000002, GO:0008233=PMID:12297508, GO:0043161=PMID:16717086, GO:0005634=PMID:8703017, GO:0016021=PMID:12297508, GO:0000775=PMID:16580887} Q96B13 Protein phosphatase 2, regulatory subunit B', gamma isoform protein 20050308 {GO:0005515=IPI, GO:0007165=IEA, GO:0008285=IDA, GO:0016485=IDA, GO:0008601=IEA, GO:0000159=IEA, GO:0008233=IDA, GO:0043161=IMP, GO:0005634=IDA, GO:0016021=IDA, GO:0000775=IDA} negative regulation of cell proliferation, proteasomal ubiquitin-dependent protein catabolic process, protein processing, signal transduction chromosome, centromeric region, integral to membrane, nucleus, protein phosphatase type 2A complex peptidase activity, protein binding, protein phosphatase type 2A regulator activity Human PPP2R5D IntAct UniProtKB {GO:0005515=PMID:19293187, GO:0034142=Reactome:REACT_6894, GO:0008601=GO_REF:0000002, GO:0000159=GO_REF:0000002, GO:0005634=PMID:8703017, GO:0044281=Reactome:REACT_111217, GO:0051403=Reactome:REACT_21308, GO:0006096=Reactome:REACT_1383, GO:0005829=Reactome:REACT_15438, GO:0002756=Reactome:REACT_6809, GO:0002755=Reactome:REACT_27215, GO:0006006=Reactome:REACT_723, GO:0004722=Reactome:REACT_15438, GO:0034138=Reactome:REACT_6783, GO:0048011=Reactome:REACT_11061, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0005975=Reactome:REACT_474, GO:0034134=Reactome:REACT_7980, GO:0002224=Reactome:REACT_9020, GO:0007399=PMID:8703017, GO:0007165=GO_REF:0000002, GO:0006112=Reactome:REACT_1505, GO:0045087=Reactome:REACT_6802, GO:0034166=Reactome:REACT_9027, GO:0035666=Reactome:REACT_25281, GO:0005654=Reactome:REACT_12539, GO:0034146=Reactome:REACT_9061, GO:0034162=Reactome:REACT_9047} Q14738 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform protein 20130415 {GO:0005515=IPI, GO:0034142=TAS, GO:0008601=IEA, GO:0000159=IEA, GO:0005634=TAS, GO:0044281=TAS, GO:0051403=TAS, GO:0006096=TAS, GO:0005829=TAS, GO:0002756=TAS, GO:0002755=TAS, GO:0006006=TAS, GO:0004722=TAS, GO:0034138=TAS, GO:0048011=TAS, GO:0038124=TAS, GO:0038123=TAS, GO:0005975=TAS, GO:0034134=TAS, GO:0002224=TAS, GO:0007399=TAS, GO:0007165=IEA, GO:0006112=TAS, GO:0045087=TAS, GO:0034166=TAS, GO:0035666=TAS, GO:0005654=TAS, GO:0034146=TAS, GO:0034162=TAS} MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, carbohydrate metabolic process, energy reserve metabolic process, glucose metabolic process, glycolysis, innate immune response, nervous system development, neurotrophin TRK receptor signaling pathway, signal transduction, small molecule metabolic process, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway cytosol, nucleoplasm, nucleus, protein phosphatase type 2A complex protein binding, protein phosphatase type 2A regulator activity, protein serine/threonine phosphatase activity Human UniProtKB:P30153 PPP2R5E HPA UniProtKB {GO:0005515=PMID:19156129, GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0008601=GO_REF:0000002, GO:0000159=GO_REF:0000002, GO:0043231=GO_REF:0000052} Q16537 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform protein 20080205 {GO:0005515=IPI, GO:0007165=IEA, GO:0005737=IDA, GO:0008601=IEA, GO:0000159=IEA, GO:0043231=IDA} signal transduction cytoplasm, intracellular membrane-bounded organelle, protein phosphatase type 2A complex protein binding, protein phosphatase type 2A regulator activity Human PPP3CA HPA UniProtKB {GO:0005515=PMID:17474147, GO:0005516=PMID:11005320, GO:0030018=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0006606=GO_REF:0000019, GO:0014883=GO_REF:0000019, GO:0005829=Reactome:REACT_118703, GO:0005739=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0000082=GO_REF:0000019, GO:0006470=PMID:18815128, GO:0008144=PMID:11005320, GO:0045944=GO_REF:0000019, GO:0046983=PMID:11005320, GO:0004723=GO_REF:0000019, GO:0004721=GO_REF:0000003, GO:0006816=GO_REF:0000019, GO:0004722=PMID:8392375, GO:0071333=GO_REF:0000019, GO:0005955=PMID:8392375, GO:0046676=GO_REF:0000019, GO:0033192=PMID:18815128, GO:0046982=GO_REF:0000019, GO:0005509=PMID:8392375, GO:0033173=GO_REF:0000019, GO:0060079=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0006950=GO_REF:0000019, GO:0048741=GO_REF:0000019, GO:0050804=GO_REF:0000019, GO:0035690=PMID:11005320, GO:0051592=PMID:18815128, GO:0042110=PMID:11005320, GO:0001975=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0016311=PMID:2556704, GO:0019899=PMID:11005320} Q08209 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform protein 20101115 {GO:0005515=IPI, GO:0005516=IDA, GO:0030018=IEA, GO:0005634=IDA, GO:0006606=IEA, GO:0014883=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0005737=IDA, GO:0000082=IEA, GO:0006470=IDA, GO:0008144=IDA, GO:0045944=IEA, GO:0046983=IPI, GO:0004723=IEA, GO:0004721=IEA, GO:0006816=IEA, GO:0004722=NAS, GO:0071333=IEA, GO:0005955=NAS, GO:0046676=IEA, GO:0033192=IDA, GO:0046982=IEA, GO:0005509=NAS, GO:0033173=IEA, GO:0060079=IEA, GO:0005730=IDA, GO:0006950=IEA, GO:0048741=IEA, GO:0050804=IEA, GO:0035690=IDA, GO:0051592=IDA, GO:0042110=TAS, GO:0001975=IEA, GO:0016020=IEA, GO:0016311=TAS, GO:0019899=IDA} G1/S transition of mitotic cell cycle, T cell activation, calcineurin-NFAT signaling cascade, calcium ion transport, cellular response to drug, cellular response to glucose stimulus, dephosphorylation, negative regulation of insulin secretion, positive regulation of transcription from RNA polymerase II promoter, protein dephosphorylation, protein import into nucleus, regulation of excitatory postsynaptic membrane potential, regulation of synaptic transmission, response to amphetamine, response to calcium ion, response to stress, skeletal muscle fiber development, transition between fast and slow fiber Z disc, calcineurin complex, cytoplasm, cytosol, membrane, mitochondrion, nucleolus, nucleus calcium ion binding, calcium-dependent protein serine/threonine phosphatase activity, calmodulin binding, calmodulin-dependent protein phosphatase activity, drug binding, enzyme binding, phosphoprotein phosphatase activity, protein binding, protein dimerization activity, protein heterodimerization activity, protein serine/threonine phosphatase activity Human PPP3CB UniProtKB UniProtKB {GO:0005515=PMID:21903422, GO:0005516=PMID:11005320, GO:0030346=PMID:2556704, GO:0005886=GO_REF:0000024, GO:0048675=PMID:21531385, GO:0005829=Reactome:REACT_118703, GO:0007507=GO_REF:0000019, GO:0006470=GO_REF:0000024, GO:0042098=PMID:8978785, GO:0048167=PMID:21531385, GO:0017156=GO_REF:0000024, GO:0008144=PMID:11005320, GO:0046983=PMID:11005320, GO:0004721=GO_REF:0000003, GO:0007613=PMID:21531385, GO:0004722=PMID:8392375, GO:0007612=PMID:21531385, GO:0034097=GO_REF:0000019, GO:0005955=PMID:8524402, GO:0043029=GO_REF:0000019, GO:0033192=GO_REF:0000024, GO:0035774=GO_REF:0000024, GO:0005509=PMID:8524402, GO:0035690=PMID:11005320, GO:0007165=PMID:8978785, GO:0042110=PMID:11005320, GO:0050796=GO_REF:0000024, GO:0030217=GO_REF:0000019, GO:0016311=PMID:2556704, GO:0001915=GO_REF:0000019, GO:0035176=PMID:21531385, GO:0006468=GO_REF:0000024, GO:0019899=PMID:11005320} Q5F2F8 Serine/threonine-protein phosphatase protein 20130413 {GO:0005515=IPI, GO:0005516=IDA, GO:0030346=IDA, GO:0005886=ISS, GO:0048675=TAS, GO:0005829=TAS, GO:0007507=IEA, GO:0006470=ISS, GO:0042098=NAS, GO:0048167=TAS, GO:0017156=ISS, GO:0008144=IDA, GO:0046983=IPI, GO:0004721=IEA, GO:0007613=TAS, GO:0004722=NAS, GO:0007612=TAS, GO:0034097=IEA, GO:0005955=IDA, GO:0043029=IEA, GO:0033192=ISS, GO:0035774=ISS, GO:0005509=IDA, GO:0035690=IDA, GO:0007165=NAS, GO:0042110=TAS, GO:0050796=ISS, GO:0030217=IEA, GO:0016311=TAS, GO:0001915=IEA, GO:0035176=IEP, GO:0006468=ISS, GO:0019899=IDA} T cell activation, T cell differentiation, T cell homeostasis, T cell proliferation, axon extension, calcium ion-dependent exocytosis, cellular response to drug, dephosphorylation, heart development, learning, memory, negative regulation of T cell mediated cytotoxicity, positive regulation of insulin secretion involved in cellular response to glucose stimulus, protein dephosphorylation, protein phosphorylation, regulation of insulin secretion, regulation of synaptic plasticity, response to cytokine stimulus, signal transduction, social behavior calcineurin complex, cytosol, plasma membrane calcium ion binding, calmodulin binding, calmodulin-dependent protein phosphatase activity, drug binding, enzyme binding, phosphoprotein phosphatase activity, protein binding, protein dimerization activity, protein phosphatase 2B binding, protein serine/threonine phosphatase activity Human EC:3.1.3.16 PPP3CC Reactome UniProtKB {GO:0005516=GO_REF:0000037, GO:1900740=Reactome:REACT_697, GO:0016787=GO_REF:0000002, GO:0006915=Reactome:REACT_578, GO:0004721=GO_REF:0000003, GO:0097193=Reactome:REACT_964, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_1663} P48454 Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform protein 20130213 {GO:0005516=IEA, GO:1900740=TAS, GO:0016787=IEA, GO:0006915=TAS, GO:0004721=IEA, GO:0097193=TAS, GO:0046872=IEA, GO:0005829=TAS} apoptotic process, intrinsic apoptotic signaling pathway, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway cytosol calmodulin binding, hydrolase activity, metal ion binding, phosphoprotein phosphatase activity Human PPP3R1 BHF-UCL UniProtKB {GO:0005516=PMID:2558868, GO:1900740=Reactome:REACT_697, GO:0019904=PMID:20639889, GO:0005509=PMID:2558868, GO:0004723=PMID:2558868, GO:0006915=Reactome:REACT_578, GO:0005955=PMID:2558868, GO:0097193=Reactome:REACT_964, GO:0005829=Reactome:REACT_118703} P63098 Calcineurin subunit B type 1 protein 20121203 {GO:0005516=NAS, GO:1900740=TAS, GO:0019904=IPI, GO:0005509=NAS, GO:0004723=NAS, GO:0006915=TAS, GO:0005955=NAS, GO:0097193=TAS, GO:0005829=TAS} apoptotic process, intrinsic apoptotic signaling pathway, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway calcineurin complex, cytosol calcium ion binding, calcium-dependent protein serine/threonine phosphatase activity, calmodulin binding, protein domain specific binding Human UniProtKB:Q99828 PPP3R2 InterPro UniProtKB {GO:0005509=GO_REF:0000002} Q96LZ3 Calcineurin subunit B type 2 protein 20130413 {GO:0005509=IEA} calcium ion binding Human InterPro:IPR001125|InterPro:IPR002048|InterPro:IPR011992 PPP4C GOC UniProtKB {GO:0005515=PMID:19156129, GO:0005813=GO_REF:0000029, GO:0005886=GO_REF:0000052, GO:0000226=GO_REF:0000029, GO:0005634=GO_REF:0000052, GO:0038061=PMID:9837938, GO:0046872=GO_REF:0000029, GO:0010569=PMID:20154705, GO:0030289=GO_REF:0000019, GO:0004704=PMID:9837938, GO:0005737=GO_REF:0000052, GO:0016787=GO_REF:0000002, GO:0004721=GO_REF:0000003, GO:0004722=PMID:20154705} P60510 Serine/threonine-protein phosphatase 4 catalytic subunit protein 20130413 {GO:0005515=IPI, GO:0005813=NAS, GO:0005886=IDA, GO:0000226=NAS, GO:0005634=IDA, GO:0038061=NAS, GO:0046872=NAS, GO:0010569=IMP, GO:0030289=IEA, GO:0004704=NAS, GO:0005737=IDA, GO:0016787=IEA, GO:0004721=IEA, GO:0004722=IDA} NIK/NF-kappaB cascade, microtubule cytoskeleton organization, regulation of double-strand break repair via homologous recombination centrosome, cytoplasm, nucleus, plasma membrane, protein phosphatase 4 complex NF-kappaB-inducing kinase activity, hydrolase activity, metal ion binding, phosphoprotein phosphatase activity, protein binding, protein serine/threonine phosphatase activity Human PPP4R1 IntAct UniProtKB {GO:0005515=PMID:18715871, GO:0030289=GO_REF:0000024, GO:0007165=PMID:10026142, GO:0030362=PMID:10026142, GO:0004721=GO_REF:0000024, GO:0006468=GO_REF:0000024} Q8TF05 Serine/threonine-protein phosphatase 4 regulatory subunit 1 protein 20130415 {GO:0005515=IPI, GO:0030289=ISS, GO:0007165=NAS, GO:0030362=NAS, GO:0004721=ISS, GO:0006468=ISS} protein phosphorylation, signal transduction protein phosphatase 4 complex phosphoprotein phosphatase activity, protein binding, protein phosphatase type 4 regulator activity Human UniProtKB:P60510 PPP4R2 HPA UniProtKB {GO:0005515=PMID:19156129, GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0030289=PMID:20154705, GO:0005813=PMID:10769191, GO:0005737=GO_REF:0000052, GO:0030362=PMID:20154705, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0030674=PMID:20154705, GO:0006464=PMID:10769191, GO:0010569=PMID:20154705} Q9NY27 Serine/threonine-protein phosphatase 4 regulatory subunit 2 protein 20101115 {GO:0005515=IPI, GO:0008380=IEA, GO:0006397=IEA, GO:0030289=IDA, GO:0005813=TAS, GO:0005737=IDA, GO:0030362=IMP, GO:0005730=IDA, GO:0005634=IDA, GO:0030674=IMP, GO:0006464=TAS, GO:0010569=IMP} RNA splicing, cellular protein modification process, mRNA processing, regulation of double-strand break repair via homologous recombination centrosome, cytoplasm, nucleolus, nucleus, protein phosphatase 4 complex protein binding, protein binding, bridging, protein phosphatase type 4 regulator activity Human PPP4R4 HPA UniProtKB {GO:0005515=PMID:18715871, GO:0008287=PMID:18715871, GO:0005737=GO_REF:0000052, GO:0019888=PMID:18715871, GO:0080163=PMID:18715871, GO:0032515=PMID:18715871} Q6NUP7 Serine/threonine-protein phosphatase 4 regulatory subunit 4 protein 20111111 {GO:0005515=IPI, GO:0008287=IDA, GO:0005737=IDA, GO:0019888=IDA, GO:0080163=IDA, GO:0032515=IDA} negative regulation of phosphoprotein phosphatase activity, regulation of protein serine/threonine phosphatase activity cytoplasm, protein serine/threonine phosphatase complex protein binding, protein phosphatase regulator activity Human PPP5C GOC UniProtKB {GO:0005515=PMID:21360678, GO:0043005=GO_REF:0000019, GO:0005794=GO_REF:0000052, GO:0005634=GO_REF:0000039, GO:0043278=GO_REF:0000019, GO:0051291=GO_REF:0000019, GO:0006351=PMID:7925273, GO:0046872=GO_REF:0000037, GO:0042802=PMID:21360678, GO:0005829=GO_REF:0000019, GO:0007165=PMID:12761501, GO:0007067=PMID:7925273, GO:0005737=GO_REF:0000052, GO:0006470=GO_REF:0000002, GO:0043025=GO_REF:0000019, GO:0004721=PMID:9383998, GO:0004722=PMID:7925273, GO:0004871=PMID:12761501, GO:0043123=PMID:12761501} P53041 Serine/threonine-protein phosphatase 5 protein 20130413 {GO:0005515=IPI, GO:0043005=IEA, GO:0005794=IDA, GO:0005634=IEA, GO:0043278=IEA, GO:0051291=IEA, GO:0006351=TAS, GO:0046872=IEA, GO:0042802=IPI, GO:0005829=IEA, GO:0007165=IMP, GO:0007067=TAS, GO:0005737=IDA, GO:0006470=IEA, GO:0043025=IEA, GO:0004721=ISS, GO:0004722=TAS, GO:0004871=IMP, GO:0043123=IMP} mitosis, positive regulation of I-kappaB kinase/NF-kappaB cascade, protein dephosphorylation, protein heterooligomerization, response to morphine, signal transduction, transcription, DNA-dependent Golgi apparatus, cytoplasm, cytosol, neuron projection, neuronal cell body, nucleus identical protein binding, metal ion binding, phosphoprotein phosphatase activity, protein binding, protein serine/threonine phosphatase activity, signal transducer activity Human PPP6C InterPro UniProtKB {GO:0005515=PMID:18186651, GO:0000082=PMID:9013334, GO:0006470=PMID:16716191, GO:0016787=GO_REF:0000002, GO:0004722=PMID:16716191, GO:0046872=GO_REF:0000037, GO:0005829=PMID:16716191} Q5T1S7 Serine/threonine-protein phosphatase 6 catalytic subunit protein 20130413 {GO:0005515=IPI, GO:0000082=TAS, GO:0006470=IDA, GO:0016787=IEA, GO:0004722=IDA, GO:0046872=IEA, GO:0005829=IDA} G1/S transition of mitotic cell cycle, protein dephosphorylation cytosol hydrolase activity, metal ion binding, protein binding, protein serine/threonine phosphatase activity Human InterPro:IPR004843|InterPro:IPR006186 PPP6R1 HPA UniProtKB {GO:0005515=PMID:18186651, GO:0005737=GO_REF:0000052, GO:0019903=PMID:16716191, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0043666=PMID:16716191} Q9UPN7 Serine/threonine-protein phosphatase 6 regulatory subunit 1 protein 20111111 {GO:0005515=IPI, GO:0005737=IDA, GO:0019903=IPI, GO:0005730=IDA, GO:0005634=IDA, GO:0043666=IDA} regulation of phosphoprotein phosphatase activity cytoplasm, nucleolus, nucleus protein binding, protein phosphatase binding Human PPP6R2 HPA UniProtKB {GO:0005515=PMID:18186651, GO:0005737=GO_REF:0000052, GO:0043231=GO_REF:0000052} O75170 Serine/threonine-protein phosphatase 6 regulatory subunit 2 protein 20101115 {GO:0005515=IPI, GO:0005737=IDA, GO:0043231=IDA} cytoplasm, intracellular membrane-bounded organelle protein binding Human PPP6R3 IntAct UniProtKB {GO:0005515=PMID:18186651, GO:0005737=GO_REF:0000039, GO:0019903=PMID:16716191, GO:0043666=PMID:16716191, GO:0005634=GO_REF:0000039} Q5H9R7 Serine/threonine-protein phosphatase 6 regulatory subunit 3 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0019903=IPI, GO:0043666=IDA, GO:0005634=IEA} regulation of phosphoprotein phosphatase activity cytoplasm, nucleus protein binding, protein phosphatase binding Human UniProtKB:O15084 PPRC1 HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q5VV67 Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 protein 20110516 {GO:0006355=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus, nucleus RNA binding, nucleic acid binding, nucleotide binding NOT Human PPT1 InterPro UniProtKB {GO:0031579=PMID:15929065, GO:0030424=PMID:12483688, GO:0008344=GO_REF:0000019, GO:0006907=PMID:16542649, GO:0030308=PMID:10737604, GO:0005634=PMID:10992246, GO:0015031=PMID:10737604, GO:0005764=PMID:8895569, GO:0005615=GO_REF:0000019, GO:0007269=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0005829=GO_REF:0000024, GO:0002084=PMID:10737604, GO:0030163=PMID:10740217, GO:0043524=PMID:10737604, GO:0048666=PMID:11136716, GO:0043025=GO_REF:0000019, GO:0007625=GO_REF:0000019, GO:0044257=GO_REF:0000019, GO:0051186=PMID:16542649, GO:0008306=GO_REF:0000019, GO:0032429=GO_REF:0000019, GO:0043066=PMID:15929065, GO:0005794=PMID:7637805, GO:0008474=GO_REF:0000002, GO:0016290=GO_REF:0000024, GO:0030149=PMID:16542649, GO:0051181=PMID:16542649, GO:0050803=PMID:11136716, GO:0048549=PMID:16542649, GO:0005576=PMID:8895569, GO:0006898=PMID:16542649, GO:0008021=PMID:12483688, GO:0007399=PMID:7637805, GO:0016042=PMID:8816748, GO:0007420=PMID:7637805, GO:0006309=PMID:15929065, GO:0048260=PMID:16542649, GO:0045121=PMID:15929065, GO:0007042=PMID:11722572, GO:0007601=GO_REF:0000019, GO:0007040=GO_REF:0000019, GO:0006464=GO_REF:0000002} Q5T0S4 Palmitoyl-protein thioesterase 1 protein 20130413 {GO:0031579=IMP, GO:0030424=IDA, GO:0008344=IEA, GO:0006907=IMP, GO:0030308=IMP, GO:0005634=IDA, GO:0015031=IMP, GO:0005764=IDA, GO:0005615=IEA, GO:0007269=IEA, GO:0030425=IEA, GO:0005829=ISS, GO:0002084=IDA, GO:0030163=NAS, GO:0043524=IMP, GO:0048666=TAS, GO:0043025=IEA, GO:0007625=IEA, GO:0044257=IEA, GO:0051186=IMP, GO:0008306=IEA, GO:0032429=IEA, GO:0043066=IDA, GO:0005794=IDA, GO:0008474=IEA, GO:0016290=ISS, GO:0030149=TAS, GO:0051181=IMP, GO:0050803=NAS, GO:0048549=IMP, GO:0005576=IDA, GO:0006898=IMP, GO:0008021=IDA, GO:0007399=IMP, GO:0016042=IDA, GO:0007420=IMP, GO:0006309=IDA, GO:0048260=IMP, GO:0045121=IDA, GO:0007042=IMP, GO:0007601=IEA, GO:0007040=IEA, GO:0006464=IEA} adult locomotory behavior, apoptotic DNA fragmentation, associative learning, brain development, cellular protein catabolic process, cellular protein modification process, cofactor metabolic process, cofactor transport, grooming behavior, lipid catabolic process, lysosomal lumen acidification, lysosome organization, membrane raft organization, negative regulation of apoptotic process, negative regulation of cell growth, negative regulation of neuron apoptotic process, nervous system development, neuron development, neurotransmitter secretion, pinocytosis, positive regulation of pinocytosis, positive regulation of receptor-mediated endocytosis, protein catabolic process, protein depalmitoylation, protein transport, receptor-mediated endocytosis, regulation of phospholipase A2 activity, regulation of synapse structure and activity, sphingolipid catabolic process, visual perception Golgi apparatus, axon, cytosol, dendrite, extracellular region, extracellular space, lysosome, membrane raft, neuronal cell body, nucleus, synaptic vesicle palmitoyl-(protein) hydrolase activity, palmitoyl-CoA hydrolase activity Human InterPro:IPR002472 PPT2 UniProtKB UniProtKB {GO:0005783=GO_REF:0000054, GO:0008474=PMID:10417332, GO:0005764=PMID:9341199, GO:0016790=PMID:9341199, GO:0006464=PMID:9341199} Q9UMR5 Lysosomal thioesterase PPT2 protein 20020702 {GO:0005783=IDA, GO:0008474=NAS, GO:0005764=NAS, GO:0016790=NAS, GO:0006464=NAS} cellular protein modification process endoplasmic reticulum, lysosome palmitoyl-(protein) hydrolase activity, thiolester hydrolase activity Human PPTC7 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0004721=GO_REF:0000003, GO:0046872=GO_REF:0000037} Q8NI37 Protein phosphatase PTC7 homolog protein 20130413 {GO:0005739=IEA, GO:0004721=IEA, GO:0046872=IEA} mitochondrion metal ion binding, phosphoprotein phosphatase activity Human Ensembl:ENSMUSP00000051838 PPWD1 HPA UniProtKB {GO:0000398=PMID:11991638, GO:0006457=GO_REF:0000037, GO:0003755=GO_REF:0000003, GO:0005634=GO_REF:0000052, GO:0071013=PMID:11991638} Q96BP3 Peptidylprolyl isomerase domain and WD repeat-containing protein 1 protein 20101115 {GO:0000398=IC, GO:0006457=IEA, GO:0003755=IEA, GO:0005634=IDA, GO:0071013=IDA} mRNA splicing, via spliceosome, protein folding catalytic step 2 spliceosome, nucleus peptidyl-prolyl cis-trans isomerase activity Human PPY Reactome UniProtKB {GO:0009306=PMID:2997153, GO:0005179=GO_REF:0000037, GO:0007586=PMID:6373251, GO:0005102=PMID:6373251, GO:0005576=Reactome:REACT_22289} P01298 Pancreatic prohormone protein 20081217 {GO:0009306=TAS, GO:0005179=IEA, GO:0007586=TAS, GO:0005102=TAS, GO:0005576=TAS} digestion, protein secretion extracellular region hormone activity, receptor binding Human PQBP1 HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0034063=PMID:21933836, GO:0071598=GO_REF:0000019, GO:0010494=GO_REF:0000019, GO:0003713=PMID:10198427, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=PMID:9875212, GO:0006351=GO_REF:0000037} O60828 Polyglutamine-binding protein 1 protein 20101115 {GO:0006355=IEA, GO:0005737=IDA, GO:0034063=IDA, GO:0071598=IEA, GO:0010494=IEA, GO:0003713=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=TAS, GO:0006351=IEA} regulation of transcription, DNA-dependent, stress granule assembly, transcription, DNA-dependent cytoplasm, cytoplasmic stress granule, neuronal ribonucleoprotein granule, nucleolus, nucleus DNA binding, transcription coactivator activity Human PQLC1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8N2U9 PQ-loop repeat-containing protein 1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 PRADC1 UniProtKB UniProtKB {GO:0005576=PMID:15498570} Q9BSG0 Protease-associated domain-containing protein 1 protein 20041203 {GO:0005576=IDA} extracellular region Human PRAF2 UniProtKB UniProtKB {GO:0015813=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0010008=GO_REF:0000039} O60831 PRA1 family protein 2 protein 20050218 {GO:0015813=ISS, GO:0016021=IEA, GO:0015031=IEA, GO:0010008=IEA} L-glutamate transport, protein transport endosome membrane, integral to membrane Human UniProtKB:Q8R5J9 PRAM1 IntAct UniProtKB {GO:0005515=PMID:21163940, GO:0043313=GO_REF:0000019, GO:0007229=GO_REF:0000019, GO:0008289=GO_REF:0000037} Q96QH2 PML-RARA-regulated adapter molecule 1 protein 20130415 {GO:0005515=IPI, GO:0043313=IEA, GO:0007229=IEA, GO:0008289=IEA} integrin-mediated signaling pathway, regulation of neutrophil degranulation lipid binding, protein binding Human UniProtKB:Q9H0A6 PRAME UniProtKB UniProtKB {GO:0005515=PMID:16179254, GO:0008284=PMID:16179254, GO:0043066=PMID:16179254, GO:0005886=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0042974=PMID:16179254, GO:0006351=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0048387=PMID:16179254, GO:0045596=PMID:16179254, GO:0045892=PMID:16179254, GO:0040008=GO_REF:0000037} P78395 Melanoma antigen preferentially expressed in tumors protein 20090921 {GO:0005515=IPI, GO:0008284=IDA, GO:0043066=IDA, GO:0005886=IEA, GO:0006915=IEA, GO:0005634=IEA, GO:0042974=IDA, GO:0006351=IEA, GO:0030154=IEA, GO:0048387=IDA, GO:0045596=IDA, GO:0045892=IDA, GO:0040008=IEA} apoptotic process, cell differentiation, negative regulation of apoptotic process, negative regulation of cell differentiation, negative regulation of retinoic acid receptor signaling pathway, negative regulation of transcription, DNA-dependent, positive regulation of cell proliferation, regulation of growth, transcription, DNA-dependent nucleus, plasma membrane protein binding, retinoic acid receptor binding Human PRAMEF1 InterPro UniProtKB {GO:0043066=GO_REF:0000002, GO:0008284=GO_REF:0000002, GO:0048387=GO_REF:0000002, GO:0045596=GO_REF:0000002, GO:0042974=GO_REF:0000002, GO:0045892=GO_REF:0000002} O95521 PRAME family member 1 protein 20130413 {GO:0043066=IEA, GO:0008284=IEA, GO:0048387=IEA, GO:0045596=IEA, GO:0042974=IEA, GO:0045892=IEA} negative regulation of apoptotic process, negative regulation of cell differentiation, negative regulation of retinoic acid receptor signaling pathway, negative regulation of transcription, DNA-dependent, positive regulation of cell proliferation retinoic acid receptor binding Human InterPro:IPR026271 PRAMEF10 InterPro UniProtKB {GO:0043066=GO_REF:0000002, GO:0008284=GO_REF:0000002, GO:0048387=GO_REF:0000002, GO:0045596=GO_REF:0000002, GO:0042974=GO_REF:0000002, GO:0045892=GO_REF:0000002} O60809 PRAME family member 10 protein 20130413 {GO:0043066=IEA, GO:0008284=IEA, GO:0048387=IEA, GO:0045596=IEA, GO:0042974=IEA, GO:0045892=IEA} negative regulation of apoptotic process, negative regulation of cell differentiation, negative regulation of retinoic acid receptor signaling pathway, negative regulation of transcription, DNA-dependent, positive regulation of cell proliferation retinoic acid receptor binding Human InterPro:IPR026271 PRAMEF12 InterPro UniProtKB {GO:0043066=GO_REF:0000002, GO:0008284=GO_REF:0000002, GO:0048387=GO_REF:0000002, GO:0045596=GO_REF:0000002, GO:0042974=GO_REF:0000002, GO:0045892=GO_REF:0000002} O95522 PRAME family member 12 protein 20130413 {GO:0043066=IEA, GO:0008284=IEA, GO:0048387=IEA, GO:0045596=IEA, GO:0042974=IEA, GO:0045892=IEA} negative regulation of apoptotic process, negative regulation of cell differentiation, negative regulation of retinoic acid receptor signaling pathway, negative regulation of transcription, DNA-dependent, positive regulation of cell proliferation retinoic acid receptor binding Human InterPro:IPR026271 PRAMEF13 InterPro UniProtKB {GO:0043066=GO_REF:0000002, GO:0008284=GO_REF:0000002, GO:0048387=GO_REF:0000002, GO:0045596=GO_REF:0000002, GO:0042974=GO_REF:0000002, GO:0045892=GO_REF:0000002} Q5VWM6 PRAME family member 13 protein 20130413 {GO:0043066=IEA, GO:0008284=IEA, GO:0048387=IEA, GO:0045596=IEA, GO:0042974=IEA, GO:0045892=IEA} negative regulation of apoptotic process, negative regulation of cell differentiation, negative regulation of retinoic acid receptor signaling pathway, negative regulation of transcription, DNA-dependent, positive regulation of cell proliferation retinoic acid receptor binding Human InterPro:IPR026271 PRAMEF14 InterPro UniProtKB {GO:0043066=GO_REF:0000002, GO:0008284=GO_REF:0000002, GO:0048387=GO_REF:0000002, GO:0045596=GO_REF:0000002, GO:0042974=GO_REF:0000002, GO:0045892=GO_REF:0000002} Q5SWL7 PRAME family member 14 protein 20130413 {GO:0043066=IEA, GO:0008284=IEA, GO:0048387=IEA, GO:0045596=IEA, GO:0042974=IEA, GO:0045892=IEA} negative regulation of apoptotic process, negative regulation of cell differentiation, negative regulation of retinoic acid receptor signaling pathway, negative regulation of transcription, DNA-dependent, positive regulation of cell proliferation retinoic acid receptor binding Human InterPro:IPR026271 PRAMEF16 InterPro UniProtKB {GO:0043066=GO_REF:0000002, GO:0008284=GO_REF:0000002, GO:0048387=GO_REF:0000002, GO:0045596=GO_REF:0000002, GO:0042974=GO_REF:0000002, GO:0045892=GO_REF:0000002} Q5VWM1 PRAME family member 16 protein 20130413 {GO:0043066=IEA, GO:0008284=IEA, GO:0048387=IEA, GO:0045596=IEA, GO:0042974=IEA, GO:0045892=IEA} negative regulation of apoptotic process, negative regulation of cell differentiation, negative regulation of retinoic acid receptor signaling pathway, negative regulation of transcription, DNA-dependent, positive regulation of cell proliferation retinoic acid receptor binding Human InterPro:IPR026271 PRAMEF17 InterPro UniProtKB {GO:0043066=GO_REF:0000002, GO:0008284=GO_REF:0000002, GO:0048387=GO_REF:0000002, GO:0045596=GO_REF:0000002, GO:0042974=GO_REF:0000002, GO:0045892=GO_REF:0000002} Q5VTA0 PRAME family member 17 protein 20130413 {GO:0043066=IEA, GO:0008284=IEA, GO:0048387=IEA, GO:0045596=IEA, GO:0042974=IEA, GO:0045892=IEA} negative regulation of apoptotic process, negative regulation of cell differentiation, negative regulation of retinoic acid receptor signaling pathway, negative regulation of transcription, DNA-dependent, positive regulation of cell proliferation retinoic acid receptor binding Human InterPro:IPR026271 PRAMEF2 InterPro UniProtKB {GO:0043066=GO_REF:0000002, GO:0008284=GO_REF:0000002, GO:0048387=GO_REF:0000002, GO:0045596=GO_REF:0000002, GO:0042974=GO_REF:0000002, GO:0045892=GO_REF:0000002} O60811 PRAME family member 2 protein 20130413 {GO:0043066=IEA, GO:0008284=IEA, GO:0048387=IEA, GO:0045596=IEA, GO:0042974=IEA, GO:0045892=IEA} negative regulation of apoptotic process, negative regulation of cell differentiation, negative regulation of retinoic acid receptor signaling pathway, negative regulation of transcription, DNA-dependent, positive regulation of cell proliferation retinoic acid receptor binding Human InterPro:IPR026271 PRAMEF23 InterPro UniProtKB {GO:0043066=GO_REF:0000002, GO:0008284=GO_REF:0000002, GO:0048387=GO_REF:0000002, GO:0045596=GO_REF:0000002, GO:0042974=GO_REF:0000002, GO:0045892=GO_REF:0000002} A6NMV5 PRAME family member 23 protein 20130413 {GO:0043066=IEA, GO:0008284=IEA, GO:0048387=IEA, GO:0045596=IEA, GO:0042974=IEA, GO:0045892=IEA} negative regulation of apoptotic process, negative regulation of cell differentiation, negative regulation of retinoic acid receptor signaling pathway, negative regulation of transcription, DNA-dependent, positive regulation of cell proliferation retinoic acid receptor binding Human InterPro:IPR026271 PRAMEF4 InterPro UniProtKB {GO:0043066=GO_REF:0000002, GO:0008284=GO_REF:0000002, GO:0048387=GO_REF:0000002, GO:0045596=GO_REF:0000002, GO:0042974=GO_REF:0000002, GO:0045892=GO_REF:0000002} O60810 PRAME family member 4 protein 20130413 {GO:0043066=IEA, GO:0008284=IEA, GO:0048387=IEA, GO:0045596=IEA, GO:0042974=IEA, GO:0045892=IEA} negative regulation of apoptotic process, negative regulation of cell differentiation, negative regulation of retinoic acid receptor signaling pathway, negative regulation of transcription, DNA-dependent, positive regulation of cell proliferation retinoic acid receptor binding Human InterPro:IPR026271 PRAP1 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q96NZ9 Proline-rich acidic protein 1 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 PRB1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005576=GO_REF:0000029} P04280 Basic salivary proline-rich protein 1 protein 20050308 {GO:0003674=ND, GO:0008150=ND, GO:0005576=NAS} biological_process extracellular region molecular_function Human PRB3 UniProtKB UniProtKB {GO:0051636=PMID:1894623, GO:0008150=GO_REF:0000015, GO:0005576=PMID:1894623} Q04118 Basic salivary proline-rich protein 3 protein 20090721 {GO:0051636=NAS, GO:0008150=ND, GO:0005576=NAS} biological_process extracellular region Gram-negative bacterial cell surface binding Human PRB4 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005576=PMID:8373986} P10163 Basic salivary proline-rich protein 4 protein 20070906 {GO:0008150=ND, GO:0003674=ND, GO:0005576=NAS} biological_process extracellular region molecular_function Human PRC1 HPA UniProtKB {GO:0008017=GO_REF:0000002, GO:0005515=PMID:19447967, GO:0005886=GO_REF:0000052, GO:0019901=PMID:17351640, GO:0000022=PMID:9885575, GO:0005730=GO_REF:0000052, GO:0005819=PMID:17351640, GO:0000226=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0000910=PMID:17351640, GO:0005737=GO_REF:0000052, GO:0000922=GO_REF:0000039, GO:0015630=GO_REF:0000052, GO:0005876=PMID:9885575} O43663 Protein regulator of cytokinesis 1 protein 20110516 {GO:0008017=IEA, GO:0005515=IPI, GO:0005886=IDA, GO:0019901=IPI, GO:0000022=TAS, GO:0005730=IDA, GO:0005819=IDA, GO:0000226=IEA, GO:0005634=IDA, GO:0000910=IDA, GO:0005737=IDA, GO:0000922=IEA, GO:0015630=IDA, GO:0005876=TAS} cytokinesis, microtubule cytoskeleton organization, mitotic spindle elongation cytoplasm, microtubule cytoskeleton, nucleolus, nucleus, plasma membrane, spindle, spindle microtubule, spindle pole microtubule binding, protein binding, protein kinase binding Human PRCC HPA UniProtKB {GO:0005515=PMID:11717438, GO:0007093=PMID:11717438, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0043231=GO_REF:0000052} Q92733 Proline-rich protein PRCC protein 20100326 {GO:0005515=IPI, GO:0007093=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0043231=IDA} mitotic cell cycle checkpoint intracellular membrane-bounded organelle, nucleolus, nucleus protein binding Human PRCP IntAct UniProtKB {GO:0005515=PMID:20517885, GO:0004185=Reactome:REACT_6, GO:0005886=Reactome:REACT_6, GO:0007596=Reactome:REACT_2051, GO:0007597=Reactome:REACT_326, GO:0004180=GO_REF:0000038, GO:0006508=GO_REF:0000037, GO:0008236=GO_REF:0000002, GO:0005764=GO_REF:0000039} P42785 Lysosomal Pro-X carboxypeptidase protein 20130415 {GO:0005515=IPI, GO:0004185=TAS, GO:0005886=TAS, GO:0007596=TAS, GO:0007597=TAS, GO:0004180=IEA, GO:0006508=IEA, GO:0008236=IEA, GO:0005764=IEA} blood coagulation, blood coagulation, intrinsic pathway, proteolysis lysosome, plasma membrane carboxypeptidase activity, protein binding, serine-type carboxypeptidase activity, serine-type peptidase activity Human UniProtKB:O60883 PRDM1 PINC UniProtKB {GO:0003700=PMID:1851123, GO:0042826=GO_REF:0000019, GO:0045579=GO_REF:0000019, GO:0001893=GO_REF:0000019, GO:0001892=GO_REF:0000019, GO:0030889=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0000122=GO_REF:0000019, GO:0007281=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0010628=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0005737=PMID:21421998, GO:0045165=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0031665=GO_REF:0000019} O75626 PR domain zinc finger protein 1 protein 20030904 {GO:0003700=TAS, GO:0042826=IEA, GO:0045579=IEA, GO:0001893=IEA, GO:0001892=IEA, GO:0030889=IEA, GO:0005634=IEA, GO:0000122=IEA, GO:0007281=IEA, GO:0006351=IEA, GO:0010628=IEA, GO:0043565=IEA, GO:0005737=IDA, GO:0045165=IEA, GO:0008270=IEA, GO:0031665=IEA} cell fate commitment, embryonic placenta development, germ cell development, maternal placenta development, negative regulation of B cell proliferation, negative regulation of lipopolysaccharide-mediated signaling pathway, negative regulation of transcription from RNA polymerase II promoter, positive regulation of B cell differentiation, positive regulation of gene expression, transcription, DNA-dependent cytoplasm, nucleus histone deacetylase binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human PRDM10 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9NQV6 PR domain zinc finger protein 10 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 PRDM12 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0022008=GO_REF:0000019} Q9H4Q4 PR domain zinc finger protein 12 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0022008=IEA} neurogenesis, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 PRDM13 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0022008=GO_REF:0000019} Q9H4Q3 PR domain zinc finger protein 13 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0022008=IEA} neurogenesis, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 PRDM14 UniProtKB UniProtKB {GO:0010468=GO_REF:0000019, GO:0009566=GO_REF:0000019, GO:0000902=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0048873=GO_REF:0000019, GO:0001708=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0007281=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q9GZV8 PR domain zinc finger protein 14 protein 20130413 {GO:0010468=IEA, GO:0009566=IEA, GO:0000902=IEA, GO:0006355=IEA, GO:0048873=IEA, GO:0001708=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0007281=IEA, GO:0006351=IEA} cell fate specification, cell morphogenesis, fertilization, germ cell development, homeostasis of number of cells within a tissue, regulation of gene expression, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 PRDM16 UniProtKB UniProtKB {GO:0005515=PMID:19049980, GO:0003713=GO_REF:0000024, GO:0005634=PMID:19049980, GO:0046332=GO_REF:0000019, GO:0000122=PMID:19049980, GO:0043457=GO_REF:0000024, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0043565=PMID:12816872, GO:0050872=GO_REF:0000019, GO:0050873=GO_REF:0000024, GO:0017053=GO_REF:0000024, GO:0060021=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0045893=GO_REF:0000024, GO:0043586=GO_REF:0000019, GO:0035019=GO_REF:0000019, GO:0045892=GO_REF:0000024, GO:0030512=PMID:19049980, GO:0022008=GO_REF:0000019} Q9HAZ2 PR domain zinc finger protein 16 protein 20090813 {GO:0005515=IPI, GO:0003713=ISS, GO:0005634=IDA, GO:0046332=IEA, GO:0000122=IDA, GO:0043457=ISS, GO:0003676=IEA, GO:0006351=IEA, GO:0043565=IDA, GO:0050872=IEA, GO:0050873=ISS, GO:0017053=ISS, GO:0060021=IEA, GO:0008270=IEA, GO:0045893=ISS, GO:0043586=IEA, GO:0035019=IEA, GO:0045892=ISS, GO:0030512=IMP, GO:0022008=IEA} brown fat cell differentiation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, negative regulation of transforming growth factor beta receptor signaling pathway, neurogenesis, palate development, positive regulation of transcription, DNA-dependent, regulation of cellular respiration, somatic stem cell maintenance, tongue development, transcription, DNA-dependent, white fat cell differentiation nucleus, transcriptional repressor complex SMAD binding, nucleic acid binding, protein binding, sequence-specific DNA binding, transcription coactivator activity, zinc ion binding Human UniProtKB:A2A935 PRDM2 HPA UniProtKB {GO:0006355=GO_REF:0000002, GO:0005794=GO_REF:0000052, GO:0003700=PMID:8654390, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0018024=GO_REF:0000003} Q5THJ1 PR domain zinc finger protein 2 protein 20080205 {GO:0006355=IEA, GO:0005794=IDA, GO:0003700=NAS, GO:0008270=IEA, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA, GO:0018024=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent Golgi apparatus, nucleus DNA binding, histone-lysine N-methyltransferase activity, sequence-specific DNA binding transcription factor activity, zinc ion binding Human PRDM4 Reactome UniProtKB {GO:0007165=PMID:10552934, GO:0048011=Reactome:REACT_13776, GO:0006355=GO_REF:0000037, GO:0006366=PMID:10552934, GO:0008283=PMID:10552934, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0045786=Reactome:REACT_13695, GO:0003677=GO_REF:0000037} Q9UKN5 PR domain zinc finger protein 4 protein 20070322 {GO:0007165=TAS, GO:0048011=TAS, GO:0006355=IEA, GO:0006366=TAS, GO:0008283=TAS, GO:0005634=IEA, GO:0008270=IEA, GO:0045786=TAS, GO:0003677=IEA} cell proliferation, negative regulation of cell cycle, neurotrophin TRK receptor signaling pathway, regulation of transcription, DNA-dependent, signal transduction, transcription from RNA polymerase II promoter nucleus DNA binding, zinc ion binding Human PRDM5 IntAct UniProtKB {GO:0005515=PMID:17636019, GO:0000976=GO_REF:0000002, GO:0016575=PMID:17636019, GO:0044212=PMID:17636019, GO:0005634=PMID:17636019, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0043565=PMID:17636019, GO:0070491=PMID:17636019, GO:0008270=GO_REF:0000002, GO:0000278=PMID:17636019, GO:0045892=PMID:17636019, GO:0051567=PMID:17636019} Q9NQX1 PR domain zinc finger protein 5 protein 20130415 {GO:0005515=IPI, GO:0000976=IEA, GO:0016575=IMP, GO:0044212=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0006351=IEA, GO:0043565=IDA, GO:0070491=IDA, GO:0008270=IEA, GO:0000278=IMP, GO:0045892=IDA, GO:0051567=IDA} histone H3-K9 methylation, histone deacetylation, mitotic cell cycle, negative regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus nucleic acid binding, protein binding, repressing transcription factor binding, sequence-specific DNA binding, transcription regulatory region DNA binding, transcription regulatory region sequence-specific DNA binding, zinc ion binding Human UniProtKB:Q99684 PRDM8 UniProtKB UniProtKB {GO:0021540=GO_REF:0000019, GO:0021957=GO_REF:0000019, GO:0003714=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0046974=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0045892=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q9NQV8 PR domain zinc finger protein 8 protein 20130413 {GO:0021540=IEA, GO:0021957=IEA, GO:0003714=IEA, GO:0003682=IEA, GO:0046974=IEA, GO:0008270=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0045892=IEA, GO:0006351=IEA} corpus callosum morphogenesis, corticospinal tract morphogenesis, negative regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, chromatin binding, histone methyltransferase activity (H3-K9 specific), transcription corepressor activity, zinc ion binding Human UniProtKB-SubCell:SL-0191 PRDX1 HPA UniProtKB {GO:0005515=PMID:17909037, GO:0042345=GO_REF:0000019, GO:0042470=GO_REF:0000039, GO:0005782=GO_REF:0000019, GO:0005719=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:0042267=GO_REF:0000019, GO:0005730=GO_REF:0000019, GO:0034101=GO_REF:0000019, GO:0005634=PMID:17603937, GO:0008379=PMID:18606987, GO:0032872=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0005739=GO_REF:0000052, GO:0001501=PMID:8089076, GO:0005737=PMID:17603937, GO:0004601=PMID:11986303, GO:0005759=GO_REF:0000019, GO:0019430=GO_REF:0000019, GO:0042744=PMID:18606987, GO:0020037=GO_REF:0000019} Q06830 Peroxiredoxin-1 protein 20080205 {GO:0005515=IPI, GO:0042345=IEA, GO:0042470=IEA, GO:0005782=IEA, GO:0005719=IEA, GO:0008283=IEA, GO:0042267=IEA, GO:0005730=IEA, GO:0034101=IEA, GO:0005634=IDA, GO:0008379=IDA, GO:0032872=IEA, GO:0042803=IEA, GO:0005829=IEA, GO:0005739=IDA, GO:0001501=TAS, GO:0005737=IDA, GO:0004601=IDA, GO:0005759=IEA, GO:0019430=IEA, GO:0042744=IDA, GO:0020037=IEA} cell proliferation, erythrocyte homeostasis, hydrogen peroxide catabolic process, natural killer cell mediated cytotoxicity, regulation of NF-kappaB import into nucleus, regulation of stress-activated MAPK cascade, removal of superoxide radicals, skeletal system development cytoplasm, cytosol, melanosome, mitochondrial matrix, mitochondrion, nuclear euchromatin, nucleolus, nucleus, peroxisomal matrix heme binding, peroxidase activity, protein binding, protein homodimerization activity, thioredoxin peroxidase activity Human PRDX2 BHF-UCL UniProtKB {GO:0005737=PMID:16130169, GO:0043066=PMID:16130169, GO:0043524=GO_REF:0000019, GO:0016209=PMID:8144038, GO:0019430=PMID:20978343, GO:0016491=GO_REF:0000002, GO:0042981=PMID:12943237, GO:0034599=PMID:20978343, GO:0042744=PMID:18606987, GO:0008379=PMID:18606987, GO:0006979=PMID:12943237, GO:0005829=GO_REF:0000019} P32119 Peroxiredoxin-2 protein 20110120 {GO:0005737=TAS, GO:0043066=TAS, GO:0043524=IEA, GO:0016209=IDA, GO:0019430=IDA, GO:0016491=IEA, GO:0042981=IMP, GO:0034599=IDA, GO:0042744=TAS, GO:0008379=TAS, GO:0006979=IMP, GO:0005829=IEA} cellular response to oxidative stress, hydrogen peroxide catabolic process, negative regulation of apoptotic process, negative regulation of neuron apoptotic process, regulation of apoptotic process, removal of superoxide radicals, response to oxidative stress cytoplasm, cytosol antioxidant activity, oxidoreductase activity, thioredoxin peroxidase activity Human PRDX3 GOC UniProtKB {GO:0005515=PMID:21850687, GO:0042542=PMID:17893648, GO:0008284=PMID:12011429, GO:0008785=PMID:7733872, GO:0008385=PMID:12492477, GO:0042802=GO_REF:0000019, GO:0005739=PMID:18262354, GO:0005737=PMID:18205602, GO:0051092=PMID:12492477, GO:0004601=GO_REF:0000037, GO:0032496=GO_REF:0000024, GO:0030099=GO_REF:0000024, GO:0043154=PMID:18262354, GO:0042744=PMID:7733872, GO:0019900=PMID:18205602, GO:0051920=GO_REF:0000003, GO:0006979=PMID:18195003, GO:0043027=PMID:18262354, GO:0033673=PMID:18205602, GO:0043066=PMID:18262354, GO:0016209=GO_REF:0000002, GO:0019901=PMID:12492477, GO:0001893=GO_REF:0000019, GO:0051881=PMID:12011429, GO:0008022=PMID:17060495, GO:0034614=PMID:18262354, GO:0007005=PMID:12011429, GO:0005769=PMID:15750338} P30048 Thioredoxin-dependent peroxide reductase, mitochondrial protein 20130413 {GO:0005515=IPI, GO:0042542=IDA, GO:0008284=IDA, GO:0008785=NAS, GO:0008385=IPI, GO:0042802=IEA, GO:0005739=IDA, GO:0005737=IDA, GO:0051092=IDA, GO:0004601=IEA, GO:0032496=ISS, GO:0030099=ISS, GO:0043154=IMP, GO:0042744=IGI, GO:0019900=IPI, GO:0051920=IEA, GO:0006979=IMP, GO:0043027=IMP, GO:0033673=IDA, GO:0043066=IMP, GO:0016209=IEA, GO:0019901=IPI, GO:0001893=IEA, GO:0051881=IMP, GO:0008022=IPI, GO:0034614=IMP, GO:0007005=IMP, GO:0005769=IDA} cellular response to reactive oxygen species, hydrogen peroxide catabolic process, maternal placenta development, mitochondrion organization, myeloid cell differentiation, negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of kinase activity, positive regulation of NF-kappaB transcription factor activity, positive regulation of cell proliferation, regulation of mitochondrial membrane potential, response to hydrogen peroxide, response to lipopolysaccharide, response to oxidative stress IkappaB kinase complex, cytoplasm, early endosome, mitochondrion alkyl hydroperoxide reductase activity, antioxidant activity, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, identical protein binding, kinase binding, peroxidase activity, peroxiredoxin activity, protein C-terminus binding, protein binding, protein kinase binding Human PRDX4 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0005739=GO_REF:0000019, GO:0016209=GO_REF:0000002, GO:0007252=PMID:9388242, GO:0072593=GO_REF:0000019, GO:0016491=GO_REF:0000002, GO:0008379=PMID:9388242, GO:0051920=GO_REF:0000002, GO:0005615=GO_REF:0000019} Q13162 Peroxiredoxin-4 protein 20130415 {GO:0005515=IPI, GO:0005739=IEA, GO:0016209=IEA, GO:0007252=TAS, GO:0072593=IEA, GO:0016491=IEA, GO:0008379=TAS, GO:0051920=IEA, GO:0005615=IEA} I-kappaB phosphorylation, reactive oxygen species metabolic process extracellular space, mitochondrion antioxidant activity, oxidoreductase activity, peroxiredoxin activity, protein binding, thioredoxin peroxidase activity Human UniProtKB:P18428 PRDX5 GOC UniProtKB {GO:0048471=PMID:10095767, GO:0043066=PMID:18262354, GO:0001016=PMID:10095767, GO:0005102=PMID:20178365, GO:0005634=PMID:10095767, GO:0031410=PMID:10095767, GO:0005829=PMID:18262354, GO:0043231=PMID:15785239, GO:0005739=PMID:10751410, GO:0004601=PMID:10521424, GO:0006954=PMID:10521424, GO:0046983=PMID:15046979, GO:0016491=GO_REF:0000002, GO:0034614=PMID:18262354, GO:0016480=PMID:10095767, GO:0043154=PMID:18262354, GO:0051920=GO_REF:0000003, GO:0006979=PMID:10521424, GO:0043027=PMID:18262354, GO:0005777=PMID:10521424} P30044 Peroxiredoxin-5, mitochondrial protein 20130413 {GO:0048471=IDA, GO:0043066=IMP, GO:0001016=IDA, GO:0005102=IPI, GO:0005634=IDA, GO:0031410=IDA, GO:0005829=IDA, GO:0043231=IDA, GO:0005739=IDA, GO:0004601=IDA, GO:0006954=TAS, GO:0046983=IDA, GO:0016491=IEA, GO:0034614=IMP, GO:0016480=IDA, GO:0043154=IMP, GO:0051920=IEA, GO:0006979=IDA, GO:0043027=IMP, GO:0005777=IDA} cellular response to reactive oxygen species, inflammatory response, negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of transcription from RNA polymerase III promoter, response to oxidative stress cytoplasmic vesicle, cytosol, intracellular membrane-bounded organelle, mitochondrion, nucleus, perinuclear region of cytoplasm, peroxisome RNA polymerase III regulatory region DNA binding, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, oxidoreductase activity, peroxidase activity, peroxiredoxin activity, protein dimerization activity, receptor binding Human PRDX6 UniProtKB UniProtKB {GO:0005515=PMID:19188445, GO:0004602=GO_REF:0000003, GO:0005737=PMID:19188445, GO:0016209=PMID:10893423, GO:0004623=PMID:10893423, GO:0016023=GO_REF:0000039, GO:0042744=GO_REF:0000019, GO:0051920=GO_REF:0000003, GO:0006979=PMID:10893423, GO:0009395=PMID:10893423, GO:0005764=GO_REF:0000039, GO:0005829=PMID:9497358} P30041 Peroxiredoxin-6 protein 20101011 {GO:0005515=IPI, GO:0004602=IEA, GO:0005737=IDA, GO:0016209=NAS, GO:0004623=IDA, GO:0016023=IEA, GO:0042744=IEA, GO:0051920=IEA, GO:0006979=IDA, GO:0009395=IDA, GO:0005764=IEA, GO:0005829=NAS} hydrogen peroxide catabolic process, phospholipid catabolic process, response to oxidative stress cytoplasm, cytoplasmic membrane-bounded vesicle, cytosol, lysosome antioxidant activity, glutathione peroxidase activity, peroxiredoxin activity, phospholipase A2 activity, protein binding Human UniProtKB:P27695 PREB HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0005783=GO_REF:0000052, GO:0005634=GO_REF:0000039, GO:0048208=Reactome:REACT_12507, GO:0015031=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0030968=Reactome:REACT_18356, GO:0006888=Reactome:REACT_11203, GO:0005789=Reactome:REACT_116123, GO:0016021=GO_REF:0000037, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0016044=Reactome:REACT_11123, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q9HCU5 Prolactin regulatory element-binding protein protein 20090616 {GO:0006355=IEA, GO:0005783=IDA, GO:0005634=IEA, GO:0048208=TAS, GO:0015031=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0030968=TAS, GO:0006888=TAS, GO:0005789=TAS, GO:0016021=IEA, GO:0006987=TAS, GO:0044267=TAS, GO:0016044=TAS, GO:0043687=TAS, GO:0018279=TAS} COPII vesicle coating, ER to Golgi vesicle-mediated transport, activation of signaling protein activity involved in unfolded protein response, cellular membrane organization, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, post-translational protein modification, protein N-linked glycosylation via asparagine, protein transport, regulation of transcription, DNA-dependent, transcription, DNA-dependent endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, nucleus DNA binding Human PRELID1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0006955=PMID:10784606, GO:0005730=GO_REF:0000052, GO:0007275=PMID:10784606, GO:0005634=GO_REF:0000052} Q9Y255 PRELI domain-containing protein 1, mitochondrial protein 20080818 {GO:0005739=IDA, GO:0006955=TAS, GO:0005730=IDA, GO:0007275=TAS, GO:0005634=IDA} immune response, multicellular organismal development mitochondrion, nucleolus, nucleus Human PRELP BHF-UCL UniProtKB {GO:0005796=Reactome:REACT_121317, GO:0005975=Reactome:REACT_474, GO:0007569=GO_REF:0000019, GO:0005578=GO_REF:0000039, GO:0005576=Reactome:REACT_121303, GO:0044281=Reactome:REACT_111217, GO:0042339=Reactome:REACT_121288, GO:0031012=PMID:22261194, GO:0001501=PMID:7592739, GO:0018146=Reactome:REACT_121120, GO:0042340=Reactome:REACT_121313, GO:0008201=GO_REF:0000019, GO:0030203=Reactome:REACT_121315, GO:0005201=GO_REF:0000002, GO:0043202=Reactome:REACT_121303} P51888 Prolargin protein 20120228 {GO:0005796=TAS, GO:0005975=TAS, GO:0007569=IEA, GO:0005578=IEA, GO:0005576=TAS, GO:0044281=TAS, GO:0042339=TAS, GO:0031012=ISS, GO:0001501=TAS, GO:0018146=TAS, GO:0042340=TAS, GO:0008201=IEA, GO:0030203=TAS, GO:0005201=IEA, GO:0043202=TAS} carbohydrate metabolic process, cell aging, glycosaminoglycan metabolic process, keratan sulfate biosynthetic process, keratan sulfate catabolic process, keratan sulfate metabolic process, skeletal system development, small molecule metabolic process Golgi lumen, extracellular matrix, extracellular region, lysosomal lumen, proteinaceous extracellular matrix extracellular matrix structural constituent, heparin binding colocalizes_with Human UniProtKB:F1S6B4 PREP PINC UniProtKB {GO:0005737=GO_REF:0000039, GO:0004252=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0008236=PMID:7959018, GO:0005634=GO_REF:0000019, GO:0070008=GO_REF:0000002} P48147 Prolyl endopeptidase protein 20030904 {GO:0005737=IEA, GO:0004252=IEA, GO:0006508=IEA, GO:0008236=TAS, GO:0005634=IEA, GO:0070008=IEA} proteolysis cytoplasm, nucleus serine-type endopeptidase activity, serine-type exopeptidase activity, serine-type peptidase activity Human PREPL UniProtKB UniProtKB {GO:0004252=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0005829=GO_REF:0000039} Q4J6C6 Prolyl endopeptidase-like protein 20130413 {GO:0004252=IEA, GO:0006508=IEA, GO:0005829=IEA} proteolysis cytosol serine-type endopeptidase activity Human UniProtKB-SubCell:SL-0091 PREX1 GOC UniProtKB {GO:0005515=PMID:21339740, GO:0048471=GO_REF:0000019, GO:0005886=PMID:12123595, GO:0006801=PMID:12123595, GO:0005100=PMID:12123595, GO:0043231=GO_REF:0000052, GO:0030426=GO_REF:0000019, GO:0005829=PMID:11955434, GO:0035556=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0005543=PMID:11955434, GO:0030833=GO_REF:0000019, GO:0032321=PMID:12123595, GO:0043198=GO_REF:0000019, GO:0030041=PMID:12123595, GO:0050773=GO_REF:0000019, GO:0042119=PMID:12123595, GO:0019899=PMID:12123595, GO:0005089=PMID:12123595} Q8TCU6 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein protein 20130413 {GO:0005515=IPI, GO:0048471=IEA, GO:0005886=TAS, GO:0006801=TAS, GO:0005100=TAS, GO:0043231=IDA, GO:0030426=IEA, GO:0005829=IDA, GO:0035556=IEA, GO:0005737=IDA, GO:0005543=IDA, GO:0030833=IEA, GO:0032321=TAS, GO:0043198=IEA, GO:0030041=TAS, GO:0050773=IEA, GO:0042119=TAS, GO:0019899=TAS, GO:0005089=TAS} actin filament polymerization, intracellular signal transduction, neutrophil activation, positive regulation of Rho GTPase activity, regulation of actin filament polymerization, regulation of dendrite development, superoxide metabolic process cytoplasm, cytosol, dendritic shaft, growth cone, intracellular membrane-bounded organelle, perinuclear region of cytoplasm, plasma membrane Rho GTPase activator activity, Rho guanyl-nucleotide exchange factor activity, enzyme binding, phospholipid binding, protein binding Human PREX2 GOC UniProtKB {GO:0035556=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0007186=PMID:15304343, GO:0032855=PMID:15304343, GO:0030675=PMID:15304343, GO:0030676=PMID:15304343} Q70Z35 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein protein 20130413 {GO:0035556=IEA, GO:0005622=IEA, GO:0005543=IEA, GO:0007186=IDA, GO:0032855=IDA, GO:0030675=IDA, GO:0030676=IDA} G-protein coupled receptor signaling pathway, intracellular signal transduction, positive regulation of Rac GTPase activity intracellular Rac GTPase activator activity, Rac guanyl-nucleotide exchange factor activity, phospholipid binding Human PRF1 UniProtKB UniProtKB {GO:0002357=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0022829=PMID:20889983, GO:0005509=GO_REF:0000024, GO:0002418=GO_REF:0000024, GO:0006915=PMID:10779745, GO:0005576=GO_REF:0000039, GO:0031904=GO_REF:0000039, GO:0051607=GO_REF:0000024, GO:0006968=PMID:10779745, GO:0019835=GO_REF:0000024, GO:0044194=GO_REF:0000024, GO:0016023=GO_REF:0000019, GO:0051260=PMID:20889983, GO:0016021=PMID:20889983} P14222 Perforin-1 protein 20101110 {GO:0002357=ISS, GO:0005886=IEA, GO:0022829=IDA, GO:0005509=ISS, GO:0002418=ISS, GO:0006915=TAS, GO:0005576=IEA, GO:0031904=IEA, GO:0051607=ISS, GO:0006968=TAS, GO:0019835=ISS, GO:0044194=ISS, GO:0016023=IEA, GO:0051260=IDA, GO:0016021=IDA} apoptotic process, cellular defense response, cytolysis, defense response to tumor cell, defense response to virus, immune response to tumor cell, protein homooligomerization cytolytic granule, cytoplasmic membrane-bounded vesicle, endosome lumen, extracellular region, integral to membrane, plasma membrane calcium ion binding, wide pore channel activity Human UniProtKB:P10820 PRG2 UniProtKB UniProtKB {GO:0030133=GO_REF:0000039, GO:0006955=GO_REF:0000002, GO:0030246=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0008201=GO_REF:0000037, GO:0042742=GO_REF:0000037} P13727 Bone marrow proteoglycan protein 20130413 {GO:0030133=IEA, GO:0006955=IEA, GO:0030246=IEA, GO:0005576=IEA, GO:0008201=IEA, GO:0042742=IEA} defense response to bacterium, immune response extracellular region, transport vesicle carbohydrate binding, heparin binding Human UniProtKB-SubCell:SL-0244 PRG4 PINC UniProtKB {GO:0006955=GO_REF:0000002, GO:0008283=PMID:10545950, GO:0005576=GO_REF:0000039, GO:0030247=GO_REF:0000002, GO:0005044=GO_REF:0000002} Q92954 Proteoglycan 4 protein 20030904 {GO:0006955=IEA, GO:0008283=TAS, GO:0005576=IEA, GO:0030247=IEA, GO:0005044=IEA} cell proliferation, immune response extracellular region polysaccharide binding, scavenger receptor activity Human PRH1 IntAct UniProtKB {GO:0005515=PMID:16203048, GO:0005615=PMID:2993301} P02810 Salivary acidic proline-rich phosphoprotein 1/2 protein 20130415 {GO:0005515=IPI, GO:0005615=TAS} extracellular space protein binding Human UniProtKB:Q8TAX7 PRH2 null null {} null null null null {} null null null PRICKLE1 BHF-UCL UniProtKB {GO:0005515=PMID:17030191, GO:0031965=PMID:16417580, GO:2000691=PMID:21199191, GO:0032436=PMID:17030191, GO:0031398=PMID:17030191, GO:0001843=PMID:21901791, GO:0005634=PMID:18922795, GO:0008270=GO_REF:0000002, GO:0006606=PMID:16417580, GO:0045892=PMID:17030191, GO:0090090=PMID:17030191, GO:0005829=PMID:18922795} Q96MT3 Prickle-like protein 1 protein 20100902 {GO:0005515=IPI, GO:0031965=IDA, GO:2000691=IDA, GO:0032436=IDA, GO:0031398=IDA, GO:0001843=IMP, GO:0005634=IDA, GO:0008270=IEA, GO:0006606=IMP, GO:0045892=IDA, GO:0090090=IDA, GO:0005829=IDA} negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cardiac muscle cell myoblast differentiation, negative regulation of transcription, DNA-dependent, neural tube closure, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of protein ubiquitination, protein import into nucleus cytosol, nuclear membrane, nucleus protein binding, zinc ion binding Human PRICKLE2 LIFEdb UniProtKB {GO:0005737=GO_REF:0000054, GO:0031965=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0016328=GO_REF:0000019, GO:0031175=GO_REF:0000019, GO:0016327=GO_REF:0000019, GO:0045197=GO_REF:0000019} Q7Z3G6 Prickle-like protein 2 protein 20100607 {GO:0005737=IDA, GO:0031965=IEA, GO:0008270=IEA, GO:0016328=IEA, GO:0031175=IEA, GO:0016327=IEA, GO:0045197=IEA} establishment or maintenance of epithelial cell apical/basal polarity, neuron projection development apicolateral plasma membrane, cytoplasm, lateral plasma membrane, nuclear membrane zinc ion binding Human PRICKLE3 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0008150=GO_REF:0000015, GO:0008270=GO_REF:0000002, GO:0005575=GO_REF:0000015} O43900 Prickle-like protein 3 protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0008270=IEA, GO:0005575=ND} biological_process cellular_component protein binding, zinc ion binding Human UniProtKB:P06241 PRIM1 Reactome UniProtKB {GO:0030894=GO_REF:0000037, GO:0003896=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0000084=Reactome:REACT_899, GO:0000082=Reactome:REACT_1783, GO:0006271=Reactome:REACT_932, GO:0000723=Reactome:REACT_7970, GO:0006270=Reactome:REACT_2244, GO:0000722=Reactome:REACT_7993, GO:0006269=PMID:8026492, GO:0005654=Reactome:REACT_8008, GO:0000278=Reactome:REACT_152, GO:0032201=Reactome:REACT_7961} P49642 DNA primase small subunit protein 20130213 {GO:0030894=IEA, GO:0003896=IEA, GO:0046872=IEA, GO:0000084=TAS, GO:0000082=TAS, GO:0006271=TAS, GO:0000723=TAS, GO:0006270=TAS, GO:0000722=TAS, GO:0006269=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0032201=TAS} DNA replication initiation, DNA replication, synthesis of RNA primer, DNA strand elongation involved in DNA replication, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, mitotic cell cycle, telomere maintenance, telomere maintenance via recombination, telomere maintenance via semi-conservative replication nucleoplasm, replisome DNA primase activity, metal ion binding Human PRIM2 Reactome UniProtKB {GO:0030894=GO_REF:0000037, GO:0051539=GO_REF:0000037, GO:0003896=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0000084=Reactome:REACT_899, GO:0006271=Reactome:REACT_932, GO:0000082=Reactome:REACT_1783, GO:0000723=Reactome:REACT_7970, GO:0006270=Reactome:REACT_2244, GO:0000722=Reactome:REACT_7993, GO:0006269=PMID:8026492, GO:0005654=Reactome:REACT_8008, GO:0000278=Reactome:REACT_152, GO:0032201=Reactome:REACT_7961} P49643 DNA primase large subunit protein 20130213 {GO:0030894=IEA, GO:0051539=IEA, GO:0003896=IEA, GO:0003677=IEA, GO:0046872=IEA, GO:0000084=TAS, GO:0006271=TAS, GO:0000082=TAS, GO:0000723=TAS, GO:0006270=TAS, GO:0000722=TAS, GO:0006269=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0032201=TAS} DNA replication initiation, DNA replication, synthesis of RNA primer, DNA strand elongation involved in DNA replication, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, mitotic cell cycle, telomere maintenance, telomere maintenance via recombination, telomere maintenance via semi-conservative replication nucleoplasm, replisome 4 iron, 4 sulfur cluster binding, DNA binding, DNA primase activity, metal ion binding Human PRIMA1 UniProtKB UniProtKB {GO:0030054=GO_REF:0000039, GO:0031226=GO_REF:0000019, GO:0045202=GO_REF:0000039, GO:0051649=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0043495=GO_REF:0000019, GO:0019899=GO_REF:0000019, GO:0042135=GO_REF:0000037} Q86XR5 Proline-rich membrane anchor 1 protein 20130413 {GO:0030054=IEA, GO:0031226=IEA, GO:0045202=IEA, GO:0051649=IEA, GO:0016021=IEA, GO:0043495=IEA, GO:0019899=IEA, GO:0042135=IEA} establishment of localization in cell, neurotransmitter catabolic process cell junction, integral to membrane, intrinsic to plasma membrane, synapse enzyme binding, protein anchor Human UniProtKB-SubCell:SL-0258 PRKAA1 UniProtKB UniProtKB {GO:0005515=PMID:23455922, GO:0006695=GO_REF:0000037, GO:0070301=GO_REF:0000019, GO:0004679=PMID:18439900, GO:0047322=GO_REF:0000003, GO:0050321=GO_REF:0000003, GO:0005622=PMID:8557660, GO:0031669=GO_REF:0000024, GO:0016055=GO_REF:0000037, GO:0045821=GO_REF:0000024, GO:0019395=GO_REF:0000019, GO:0008610=GO_REF:0000024, GO:0031588=GO_REF:0000024, GO:0006950=GO_REF:0000024, GO:0009631=GO_REF:0000019, GO:0046318=PMID:11165240, GO:0035174=GO_REF:0000024, GO:0048511=GO_REF:0000037, GO:0004691=PMID:8557660, GO:0045542=PMID:8557660, GO:0010508=GO_REF:0000024, GO:0008286=Reactome:REACT_498, GO:0050405=GO_REF:0000003, GO:0032007=GO_REF:0000024, GO:0008284=GO_REF:0000019, GO:0050995=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0051291=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_21418, GO:0000187=PMID:11546797, GO:0016324=GO_REF:0000019, GO:0031000=GO_REF:0000019, GO:0006006=GO_REF:0000019, GO:0007050=Reactome:REACT_21387, GO:0006633=GO_REF:0000037, GO:0060627=GO_REF:0000019, GO:0042149=GO_REF:0000024, GO:0019900=GO_REF:0000019, GO:0014823=GO_REF:0000019, GO:0001666=PMID:8557660, GO:0006355=GO_REF:0000037, GO:0043066=GO_REF:0000024, GO:0006914=GO_REF:0000037, GO:0071456=GO_REF:0000019, GO:0055089=GO_REF:0000024, GO:0042593=GO_REF:0000024, GO:0008022=GO_REF:0000019, GO:0005524=GO_REF:0000038, GO:0006351=GO_REF:0000037, GO:2001274=GO_REF:0000019, GO:0007165=PMID:8557660, GO:0071361=GO_REF:0000019, GO:0004672=PMID:17028174, GO:0004674=GO_REF:0000038, GO:0003682=GO_REF:0000024, GO:0042752=GO_REF:0000024, GO:2000505=GO_REF:0000024} Q96E92 PRKAA1 protein protein 20130413 {GO:0005515=IPI, GO:0006695=IEA, GO:0070301=IEA, GO:0004679=IDA, GO:0047322=IEA, GO:0050321=IEA, GO:0005622=IC, GO:0031669=ISS, GO:0016055=IEA, GO:0045821=ISS, GO:0019395=IEA, GO:0008610=ISS, GO:0031588=ISS, GO:0006950=ISS, GO:0009631=IEA, GO:0046318=NAS, GO:0035174=ISS, GO:0048511=IEA, GO:0004691=NAS, GO:0045542=NAS, GO:0010508=ISS, GO:0008286=TAS, GO:0050405=IEA, GO:0032007=ISS, GO:0008284=IEA, GO:0050995=ISS, GO:0005634=ISS, GO:0051291=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0000187=NAS, GO:0016324=IEA, GO:0031000=IEA, GO:0006006=IEA, GO:0007050=TAS, GO:0006633=IEA, GO:0060627=IEA, GO:0042149=ISS, GO:0019900=IEA, GO:0014823=IEA, GO:0001666=NAS, GO:0006355=IEA, GO:0043066=ISS, GO:0006914=IEA, GO:0071456=IEA, GO:0055089=ISS, GO:0042593=ISS, GO:0008022=IEA, GO:0005524=IEA, GO:0006351=IEA, GO:2001274=IEA, GO:0007165=TAS, GO:0071361=IEA, GO:0004672=IDA, GO:0004674=IEA, GO:0003682=ISS, GO:0042752=ISS, GO:2000505=ISS} Wnt receptor signaling pathway, activation of MAPK activity, autophagy, cell cycle arrest, cellular response to ethanol, cellular response to glucose starvation, cellular response to hydrogen peroxide, cellular response to hypoxia, cellular response to nutrient levels, cholesterol biosynthetic process, cold acclimation, fatty acid biosynthetic process, fatty acid homeostasis, fatty acid oxidation, glucose homeostasis, glucose metabolic process, insulin receptor signaling pathway, lipid biosynthetic process, negative regulation of TOR signaling cascade, negative regulation of apoptotic process, negative regulation of glucose import in response to insulin stimulus, negative regulation of glucosylceramide biosynthetic process, negative regulation of lipid catabolic process, positive regulation of autophagy, positive regulation of cell proliferation, positive regulation of cholesterol biosynthetic process, positive regulation of glycolysis, protein heterooligomerization, regulation of circadian rhythm, regulation of energy homeostasis, regulation of transcription, DNA-dependent, regulation of vesicle-mediated transport, response to activity, response to caffeine, response to hypoxia, response to stress, rhythmic process, signal transduction, transcription, DNA-dependent AMP-activated protein kinase complex, apical plasma membrane, cytosol, intracellular, nucleus "AMP-activated protein kinase activity, ATP binding, acetyl-CoA carboxylase"" kinase activity, ""hydroxymethylglutaryl-CoA reductase (NADPH)"" kinase activity, cAMP-dependent protein kinase activity, chromatin binding, histone serine kinase activity, kinase binding, metal ion binding, protein C-terminus binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, tau-protein kinase activity""" Human UniProtKB-KW:KW-0067 PRKAA2 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0050405=GO_REF:0000003, GO:0005515=PMID:18439900, GO:0006695=GO_REF:0000037, GO:0032007=GO_REF:0000024, GO:0004679=PMID:18439900, GO:0047322=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_21418, GO:0031669=GO_REF:0000024, GO:0007050=Reactome:REACT_21387, GO:0006633=GO_REF:0000037, GO:0042149=GO_REF:0000024, GO:0016055=GO_REF:0000037, GO:0045821=GO_REF:0000024, GO:0044255=Reactome:REACT_22279, GO:0043066=GO_REF:0000024, GO:0006355=GO_REF:0000037, GO:0008610=GO_REF:0000024, GO:0006853=Reactome:REACT_11082, GO:0006914=GO_REF:0000037, GO:0006950=GO_REF:0000024, GO:0055089=GO_REF:0000024, GO:0042593=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0007165=PMID:7959015, GO:0035174=GO_REF:0000024, GO:0006112=Reactome:REACT_1505, GO:0004672=PMID:7959015, GO:0042304=Reactome:REACT_1988, GO:0004674=GO_REF:0000024, GO:0003682=GO_REF:0000024, GO:0042752=GO_REF:0000024, GO:0005654=Reactome:REACT_627, GO:0006468=PMID:7959015, GO:0048511=GO_REF:0000037, GO:2000505=GO_REF:0000024, GO:0016044=Reactome:REACT_11123, GO:0010508=GO_REF:0000024} P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 protein 20130213 {GO:0008286=TAS, GO:0050405=IEA, GO:0005515=IPI, GO:0006695=IEA, GO:0032007=ISS, GO:0004679=IDA, GO:0047322=IEA, GO:0044281=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0031669=ISS, GO:0007050=TAS, GO:0006633=IEA, GO:0042149=ISS, GO:0016055=IEA, GO:0045821=ISS, GO:0044255=TAS, GO:0043066=ISS, GO:0006355=IEA, GO:0008610=ISS, GO:0006853=TAS, GO:0006914=IEA, GO:0006950=ISS, GO:0055089=ISS, GO:0042593=ISS, GO:0005524=IEA, GO:0006351=IEA, GO:0007165=TAS, GO:0035174=ISS, GO:0006112=TAS, GO:0004672=TAS, GO:0042304=TAS, GO:0004674=ISS, GO:0003682=ISS, GO:0042752=ISS, GO:0005654=TAS, GO:0006468=TAS, GO:0048511=IEA, GO:2000505=ISS, GO:0016044=TAS, GO:0010508=ISS} Wnt receptor signaling pathway, autophagy, carnitine shuttle, cell cycle arrest, cellular lipid metabolic process, cellular membrane organization, cellular response to glucose starvation, cellular response to nutrient levels, cholesterol biosynthetic process, energy reserve metabolic process, fatty acid biosynthetic process, fatty acid homeostasis, glucose homeostasis, insulin receptor signaling pathway, lipid biosynthetic process, negative regulation of TOR signaling cascade, negative regulation of apoptotic process, positive regulation of autophagy, positive regulation of glycolysis, protein phosphorylation, regulation of circadian rhythm, regulation of energy homeostasis, regulation of fatty acid biosynthetic process, regulation of transcription, DNA-dependent, response to stress, rhythmic process, signal transduction, small molecule metabolic process, transcription, DNA-dependent cytosol, nucleoplasm "AMP-activated protein kinase activity, ATP binding, acetyl-CoA carboxylase"" kinase activity, ""hydroxymethylglutaryl-CoA reductase (NADPH)"" kinase activity, chromatin binding, histone serine kinase activity, metal ion binding, protein binding, protein kinase activity, protein serine/threonine kinase activity""" Human PRKAB1 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0008286=Reactome:REACT_498, GO:0019901=GO_REF:0000019, GO:0031588=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0051291=GO_REF:0000019, GO:0005829=Reactome:REACT_21418, GO:0007165=PMID:9575201, GO:0050790=GO_REF:0000019, GO:0004672=PMID:17028174, GO:0006633=GO_REF:0000037, GO:0007050=Reactome:REACT_21387, GO:0016044=Reactome:REACT_11123} Q9Y478 5'-AMP-activated protein kinase subunit beta-1 protein 20130415 {GO:0005515=IPI, GO:0008286=TAS, GO:0019901=IEA, GO:0031588=IEA, GO:0005634=IEA, GO:0051291=IEA, GO:0005829=TAS, GO:0007165=TAS, GO:0050790=IEA, GO:0004672=IDA, GO:0006633=IEA, GO:0007050=TAS, GO:0016044=TAS} cell cycle arrest, cellular membrane organization, fatty acid biosynthetic process, insulin receptor signaling pathway, protein heterooligomerization, regulation of catalytic activity, signal transduction AMP-activated protein kinase complex, cytosol, nucleus protein binding, protein kinase activity, protein kinase binding Human UniProtKB:P54619 PRKAB2 IntAct UniProtKB {GO:0005515=PMID:23455922, GO:0008286=Reactome:REACT_498, GO:0031588=PMID:17851531, GO:0004679=PMID:21399626, GO:0006853=Reactome:REACT_11082, GO:0044281=Reactome:REACT_111217, GO:0042802=PMID:21988832, GO:0005829=Reactome:REACT_21418, GO:0007165=PMID:9575201, GO:0006112=Reactome:REACT_1505, GO:0042304=Reactome:REACT_1988, GO:0016301=GO_REF:0000038, GO:0006633=GO_REF:0000037, GO:0005654=Reactome:REACT_627, GO:0007050=Reactome:REACT_21387, GO:0044255=Reactome:REACT_22279, GO:0016044=Reactome:REACT_11123} O43741 5'-AMP-activated protein kinase subunit beta-2 protein 20130415 {GO:0005515=IPI, GO:0008286=TAS, GO:0031588=IDA, GO:0004679=IDA, GO:0006853=TAS, GO:0044281=TAS, GO:0042802=IPI, GO:0005829=TAS, GO:0007165=TAS, GO:0006112=TAS, GO:0042304=TAS, GO:0016301=IEA, GO:0006633=IEA, GO:0005654=TAS, GO:0007050=TAS, GO:0044255=TAS, GO:0016044=TAS} carnitine shuttle, cell cycle arrest, cellular lipid metabolic process, cellular membrane organization, energy reserve metabolic process, fatty acid biosynthetic process, insulin receptor signaling pathway, regulation of fatty acid biosynthetic process, signal transduction, small molecule metabolic process AMP-activated protein kinase complex, cytosol, nucleoplasm AMP-activated protein kinase activity, identical protein binding, kinase activity, protein binding Human UniProtKB:O43741 PRKACA BHF-UCL UniProtKB {GO:0005515=PMID:23455922, GO:2000810=PMID:15905176, GO:0031594=GO_REF:0000019, GO:0006094=Reactome:REACT_1520, GO:0071158=GO_REF:0000024, GO:0007243=Reactome:REACT_1525, GO:0046777=GO_REF:0000019, GO:0018105=PMID:10805756, GO:0007173=Reactome:REACT_9417, GO:0006833=Reactome:REACT_24023, GO:0019433=Reactome:REACT_494, GO:0031625=PMID:21423175, GO:0005813=PMID:21399614, GO:0001707=GO_REF:0000019, GO:0019901=PMID:11035810, GO:0005975=Reactome:REACT_474, GO:0050804=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0000278=Reactome:REACT_152, GO:0048240=GO_REF:0000024, GO:0004691=GO_REF:0000024, GO:0006629=Reactome:REACT_602, GO:0005886=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0007202=Reactome:REACT_12079, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_24992, GO:0046827=GO_REF:0000019, GO:0005739=GO_REF:0000039, GO:0071377=Reactome:REACT_1665, GO:0000086=Reactome:REACT_2203, GO:0071374=GO_REF:0000019, GO:0006006=Reactome:REACT_723, GO:0071333=PMID:19949837, GO:0034199=Reactome:REACT_15530, GO:0005952=PMID:2843813, GO:0048011=Reactome:REACT_11061, GO:0005524=GO_REF:0000029, GO:0055085=Reactome:REACT_15518, GO:0007165=Reactome:REACT_12478, GO:0045667=PMID:19949837, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0016020=PMID:15569306, GO:0061136=PMID:17565987, GO:0004674=GO_REF:0000038, GO:0007596=Reactome:REACT_604, GO:0006468=PMID:2843813} P17612 cAMP-dependent protein kinase catalytic subunit alpha protein 20120828 {GO:0005515=IPI, GO:2000810=IDA, GO:0031594=IEA, GO:0006094=TAS, GO:0071158=ISS, GO:0007243=TAS, GO:0046777=IEA, GO:0018105=IDA, GO:0007173=TAS, GO:0006833=TAS, GO:0019433=TAS, GO:0031625=IDA, GO:0005813=IDA, GO:0001707=IEA, GO:0019901=IPI, GO:0005975=TAS, GO:0050804=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:0000278=TAS, GO:0048240=ISS, GO:0004691=ISS, GO:0006629=TAS, GO:0005886=IEA, GO:0005634=IEA, GO:0007202=TAS, GO:0044281=TAS, GO:0005829=TAS, GO:0046827=IEA, GO:0005739=IEA, GO:0071377=TAS, GO:0000086=TAS, GO:0071374=IEA, GO:0006006=TAS, GO:0071333=IDA, GO:0034199=TAS, GO:0005952=NAS, GO:0048011=TAS, GO:0005524=NAS, GO:0055085=TAS, GO:0007165=TAS, GO:0045667=IDA, GO:0006112=TAS, GO:0050796=TAS, GO:0016020=IDA, GO:0061136=IDA, GO:0004674=IEA, GO:0007596=TAS, GO:0006468=NAS} G2/M transition of mitotic cell cycle, activation of phospholipase C activity, activation of protein kinase A activity, blood coagulation, carbohydrate metabolic process, cellular response to glucagon stimulus, cellular response to glucose stimulus, cellular response to parathyroid hormone stimulus, energy reserve metabolic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, gluconeogenesis, glucose metabolic process, innate immune response, intracellular protein kinase cascade, lipid metabolic process, mesoderm formation, mitotic cell cycle, neurotrophin TRK receptor signaling pathway, peptidyl-serine phosphorylation, positive regulation of cell cycle arrest, positive regulation of protein export from nucleus, protein autophosphorylation, protein phosphorylation, regulation of insulin secretion, regulation of osteoblast differentiation, regulation of proteasomal protein catabolic process, regulation of synaptic transmission, regulation of tight junction assembly, signal transduction, small molecule metabolic process, sperm capacitation, transmembrane transport, triglyceride catabolic process, water transport cAMP-dependent protein kinase complex, centrosome, cytosol, membrane, mitochondrion, neuromuscular junction, nucleus, plasma membrane ATP binding, cAMP-dependent protein kinase activity, protein binding, protein kinase binding, protein serine/threonine kinase activity, ubiquitin protein ligase binding colocalizes_with Human PRKACB IntAct UniProtKB {GO:0005515=PMID:23455922, GO:0006629=Reactome:REACT_602, GO:0048471=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0006094=Reactome:REACT_1520, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0007202=Reactome:REACT_12079, GO:0007243=Reactome:REACT_1525, GO:0005829=Reactome:REACT_24992, GO:0007173=Reactome:REACT_9417, GO:0071377=Reactome:REACT_1665, GO:0051447=GO_REF:0000019, GO:0006006=Reactome:REACT_723, GO:0019433=Reactome:REACT_494, GO:0006833=Reactome:REACT_24023, GO:0034199=Reactome:REACT_15530, GO:0031625=PMID:21423175, GO:0048011=Reactome:REACT_11061, GO:0005952=PMID:12420224, GO:0005813=PMID:21399614, GO:0000287=PMID:12420224, GO:0005975=Reactome:REACT_474, GO:0005524=PMID:12420224, GO:0055085=Reactome:REACT_15518, GO:0097338=GO_REF:0000019, GO:0007165=Reactome:REACT_12478, GO:0004672=GO_REF:0000002, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0007596=Reactome:REACT_604, GO:0004674=GO_REF:0000038, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0007188=PMID:12420224, GO:0006468=PMID:12420224, GO:0005654=Reactome:REACT_20583, GO:0004691=PMID:12420224} P22694 cAMP-dependent protein kinase catalytic subunit beta protein 20130415 {GO:0005515=IPI, GO:0006629=TAS, GO:0048471=IEA, GO:0005886=IEA, GO:0006094=TAS, GO:0007268=TAS, GO:0044281=TAS, GO:0007202=TAS, GO:0007243=TAS, GO:0005829=TAS, GO:0007173=TAS, GO:0071377=TAS, GO:0051447=IEA, GO:0006006=TAS, GO:0019433=TAS, GO:0006833=TAS, GO:0034199=TAS, GO:0031625=IDA, GO:0048011=TAS, GO:0005952=TAS, GO:0005813=IDA, GO:0000287=IDA, GO:0005975=TAS, GO:0005524=IDA, GO:0055085=TAS, GO:0097338=IEA, GO:0007165=TAS, GO:0004672=IEA, GO:0006112=TAS, GO:0050796=TAS, GO:0007596=TAS, GO:0004674=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:0007188=TAS, GO:0006468=IDA, GO:0005654=TAS, GO:0004691=IDA} activation of phospholipase C activity, activation of protein kinase A activity, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, blood coagulation, carbohydrate metabolic process, cellular response to glucagon stimulus, energy reserve metabolic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, gluconeogenesis, glucose metabolic process, innate immune response, intracellular protein kinase cascade, lipid metabolic process, negative regulation of meiotic cell cycle, neurotrophin TRK receptor signaling pathway, protein phosphorylation, regulation of insulin secretion, response to clozapine, signal transduction, small molecule metabolic process, synaptic transmission, transmembrane transport, triglyceride catabolic process, water transport cAMP-dependent protein kinase complex, centrosome, cytosol, nucleoplasm, perinuclear region of cytoplasm, plasma membrane ATP binding, cAMP-dependent protein kinase activity, magnesium ion binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, ubiquitin protein ligase binding Human UniProtKB:P08238 PRKACG Reactome UniProtKB {GO:0006629=Reactome:REACT_602, GO:0006094=Reactome:REACT_1520, GO:0044281=Reactome:REACT_111217, GO:0007283=PMID:9598317, GO:0007202=Reactome:REACT_12079, GO:0007243=Reactome:REACT_1525, GO:0005829=Reactome:REACT_24992, GO:0007173=Reactome:REACT_9417, GO:0071377=Reactome:REACT_1665, GO:0006006=Reactome:REACT_723, GO:0006833=Reactome:REACT_24023, GO:0019433=Reactome:REACT_494, GO:0034199=Reactome:REACT_15530, GO:0048011=Reactome:REACT_11061, GO:0005975=Reactome:REACT_474, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0007165=Reactome:REACT_12478, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0007596=Reactome:REACT_604, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0004691=GO_REF:0000003, GO:0008584=PMID:9598317} P22612 cAMP-dependent protein kinase catalytic subunit gamma protein 20130301 {GO:0006629=TAS, GO:0006094=TAS, GO:0044281=TAS, GO:0007283=TAS, GO:0007202=TAS, GO:0007243=TAS, GO:0005829=TAS, GO:0007173=TAS, GO:0071377=TAS, GO:0006006=TAS, GO:0006833=TAS, GO:0019433=TAS, GO:0034199=TAS, GO:0048011=TAS, GO:0005975=TAS, GO:0055085=TAS, GO:0005524=IEA, GO:0007165=TAS, GO:0006112=TAS, GO:0050796=TAS, GO:0007596=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0004691=IEA, GO:0008584=TAS} activation of phospholipase C activity, activation of protein kinase A activity, blood coagulation, carbohydrate metabolic process, cellular response to glucagon stimulus, energy reserve metabolic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, gluconeogenesis, glucose metabolic process, innate immune response, intracellular protein kinase cascade, lipid metabolic process, male gonad development, neurotrophin TRK receptor signaling pathway, regulation of insulin secretion, signal transduction, small molecule metabolic process, spermatogenesis, transmembrane transport, triglyceride catabolic process, water transport cytosol ATP binding, cAMP-dependent protein kinase activity Human PRKAG1 ENSEMBL UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005515=PMID:21988832, GO:0008603=PMID:8663446, GO:0004679=GO_REF:0000019, GO:0016208=GO_REF:0000019, GO:0019901=GO_REF:0000019, GO:0031588=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0007283=PMID:9598317, GO:0005524=GO_REF:0000019, GO:0051291=GO_REF:0000019, GO:0005829=Reactome:REACT_21418, GO:0006110=PMID:8663446, GO:0007165=PMID:2342480, GO:0050790=GO_REF:0000019, GO:0004672=PMID:17028174, GO:0043531=GO_REF:0000019, GO:0016301=GO_REF:0000038, GO:0045860=PMID:8663446, GO:0007050=Reactome:REACT_21387, GO:0006633=GO_REF:0000037, GO:0004691=PMID:9598317, GO:0016044=Reactome:REACT_11123} Q8N7V9 5'-AMP-activated protein kinase subunit gamma-1 protein 20130413 {GO:0008286=TAS, GO:0005515=IPI, GO:0008603=TAS, GO:0004679=IEA, GO:0016208=IEA, GO:0019901=IEA, GO:0031588=IEA, GO:0005634=IEA, GO:0007283=TAS, GO:0005524=IEA, GO:0051291=IEA, GO:0005829=TAS, GO:0006110=TAS, GO:0007165=TAS, GO:0050790=IEA, GO:0004672=IDA, GO:0043531=IEA, GO:0016301=IEA, GO:0045860=TAS, GO:0007050=TAS, GO:0006633=IEA, GO:0004691=TAS, GO:0016044=TAS} cell cycle arrest, cellular membrane organization, fatty acid biosynthetic process, insulin receptor signaling pathway, positive regulation of protein kinase activity, protein heterooligomerization, regulation of catalytic activity, regulation of glycolysis, signal transduction, spermatogenesis AMP-activated protein kinase complex, cytosol, nucleus ADP binding, AMP binding, AMP-activated protein kinase activity, ATP binding, cAMP-dependent protein kinase activity, cAMP-dependent protein kinase regulator activity, kinase activity, protein binding, protein kinase activity, protein kinase binding Human Ensembl:ENSRNOP00000020093 PRKAG2 BHF-UCL UniProtKB {GO:0008286=Reactome:REACT_498, GO:0008603=PMID:15877279, GO:0044281=Reactome:REACT_111217, GO:0007243=PMID:15877279, GO:0005829=Reactome:REACT_21418, GO:0006754=PMID:11371514, GO:0046324=PMID:11827995, GO:0045860=PMID:15877279, GO:0006633=GO_REF:0000037, GO:0007050=Reactome:REACT_21387, GO:0044255=Reactome:REACT_22279, GO:0010800=PMID:15877279, GO:0019901=PMID:10698692, GO:0031588=PMID:15877279, GO:0006853=Reactome:REACT_11082, GO:0005977=PMID:11827995, GO:0046320=PMID:9208914, GO:0030295=PMID:15877279, GO:0019217=PMID:15877279, GO:0005524=PMID:15877279, GO:0006110=PMID:15877279, GO:0006112=Reactome:REACT_1505, GO:0042304=Reactome:REACT_1988, GO:0043531=PMID:15877279, GO:0016126=PMID:9208914, GO:0005654=Reactome:REACT_627, GO:0006469=PMID:17255938, GO:0004862=PMID:17255938, GO:0008607=PMID:15877279, GO:0016044=Reactome:REACT_11123} Q9UGJ0 5'-AMP-activated protein kinase subunit gamma-2 protein 20081020 {GO:0008286=TAS, GO:0008603=IMP, GO:0044281=TAS, GO:0007243=IMP, GO:0005829=TAS, GO:0006754=TAS, GO:0046324=TAS, GO:0045860=IMP, GO:0006633=IEA, GO:0007050=TAS, GO:0044255=TAS, GO:0010800=IMP, GO:0019901=IDA, GO:0031588=IDA, GO:0006853=TAS, GO:0005977=IMP, GO:0046320=TAS, GO:0030295=IMP, GO:0019217=IMP, GO:0005524=IDA, GO:0006110=IMP, GO:0006112=TAS, GO:0042304=TAS, GO:0043531=IDA, GO:0016126=TAS, GO:0005654=TAS, GO:0006469=IDA, GO:0004862=IDA, GO:0008607=IMP, GO:0016044=TAS} ATP biosynthetic process, carnitine shuttle, cell cycle arrest, cellular lipid metabolic process, cellular membrane organization, energy reserve metabolic process, fatty acid biosynthetic process, glycogen metabolic process, insulin receptor signaling pathway, intracellular protein kinase cascade, negative regulation of protein kinase activity, positive regulation of peptidyl-threonine phosphorylation, positive regulation of protein kinase activity, regulation of fatty acid biosynthetic process, regulation of fatty acid metabolic process, regulation of fatty acid oxidation, regulation of glucose import, regulation of glycolysis, small molecule metabolic process, sterol biosynthetic process AMP-activated protein kinase complex, cytosol, nucleoplasm ADP binding, ATP binding, cAMP-dependent protein kinase inhibitor activity, cAMP-dependent protein kinase regulator activity, phosphorylase kinase regulator activity, protein kinase activator activity, protein kinase binding Human PRKAG3 BHF-UCL UniProtKB {GO:0008286=Reactome:REACT_498, GO:0031588=GO_REF:0000019, GO:0004679=PMID:10698692, GO:0019901=PMID:10698692, GO:0005978=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0007243=PMID:10698692, GO:0005829=Reactome:REACT_21418, GO:0015758=GO_REF:0000019, GO:0016301=GO_REF:0000038, GO:0006633=GO_REF:0000037, GO:0007050=Reactome:REACT_21387, GO:0016044=Reactome:REACT_11123} Q9UGI9 5'-AMP-activated protein kinase subunit gamma-3 protein 20081020 {GO:0008286=TAS, GO:0031588=IEA, GO:0004679=TAS, GO:0019901=IDA, GO:0005978=IEA, GO:0005524=IEA, GO:0007243=TAS, GO:0005829=TAS, GO:0015758=IEA, GO:0016301=IEA, GO:0006633=IEA, GO:0007050=TAS, GO:0016044=TAS} cell cycle arrest, cellular membrane organization, fatty acid biosynthetic process, glucose transport, glycogen biosynthetic process, insulin receptor signaling pathway, intracellular protein kinase cascade AMP-activated protein kinase complex, cytosol AMP-activated protein kinase activity, ATP binding, kinase activity, protein kinase binding Human PRKAR1A LIFEdb UniProtKB {GO:0005515=PMID:23455922, GO:0048011=Reactome:REACT_11061, GO:0005952=GO_REF:0000002, GO:0008603=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0006357=PMID:1832337, GO:0044281=Reactome:REACT_111217, GO:0007202=Reactome:REACT_12079, GO:0055085=Reactome:REACT_15518, GO:0005829=Reactome:REACT_24992, GO:0035556=PMID:1889088, GO:0043234=GO_REF:0000054, GO:0007165=Reactome:REACT_12478, GO:0030552=GO_REF:0000037, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0007173=Reactome:REACT_9417, GO:0071377=Reactome:REACT_1665, GO:0008543=Reactome:REACT_9470, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0006833=Reactome:REACT_24023, GO:0034199=Reactome:REACT_15530, GO:0031625=PMID:21423175} P10644 cAMP-dependent protein kinase type I-alpha regulatory subunit protein 20100607 {GO:0005515=IPI, GO:0048011=TAS, GO:0005952=IEA, GO:0008603=IEA, GO:0005886=IEA, GO:0006357=TAS, GO:0044281=TAS, GO:0007202=TAS, GO:0055085=TAS, GO:0005829=TAS, GO:0035556=TAS, GO:0043234=IDA, GO:0007165=TAS, GO:0030552=IEA, GO:0006112=TAS, GO:0050796=TAS, GO:0007173=TAS, GO:0071377=TAS, GO:0008543=TAS, GO:0007596=TAS, GO:0045087=TAS, GO:0006833=TAS, GO:0034199=TAS, GO:0031625=IDA} activation of phospholipase C activity, activation of protein kinase A activity, blood coagulation, cellular response to glucagon stimulus, energy reserve metabolic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, regulation of insulin secretion, regulation of transcription from RNA polymerase II promoter, signal transduction, small molecule metabolic process, transmembrane transport, water transport cAMP-dependent protein kinase complex, cytosol, plasma membrane, protein complex cAMP binding, cAMP-dependent protein kinase regulator activity, protein binding, ubiquitin protein ligase binding Human PRKAR1B Reactome UniProtKB {GO:0048011=Reactome:REACT_11061, GO:0005952=PMID:1708242, GO:0008603=PMID:1708242, GO:0005886=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0007202=Reactome:REACT_12079, GO:0055085=Reactome:REACT_15518, GO:0005829=Reactome:REACT_24992, GO:0007165=Reactome:REACT_12478, GO:0030552=GO_REF:0000037, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0007173=Reactome:REACT_9417, GO:0071377=Reactome:REACT_1665, GO:0008543=Reactome:REACT_9470, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0007611=GO_REF:0000019, GO:0006468=PMID:1708242, GO:0006833=Reactome:REACT_24023, GO:0034199=Reactome:REACT_15530} P31321 cAMP-dependent protein kinase type I-beta regulatory subunit protein 20130301 {GO:0048011=TAS, GO:0005952=NAS, GO:0008603=NAS, GO:0005886=IEA, GO:0044281=TAS, GO:0007202=TAS, GO:0055085=TAS, GO:0005829=TAS, GO:0007165=TAS, GO:0030552=IEA, GO:0006112=TAS, GO:0050796=TAS, GO:0007173=TAS, GO:0071377=TAS, GO:0008543=TAS, GO:0007596=TAS, GO:0045087=TAS, GO:0007611=IEA, GO:0006468=NAS, GO:0006833=TAS, GO:0034199=TAS} activation of phospholipase C activity, activation of protein kinase A activity, blood coagulation, cellular response to glucagon stimulus, energy reserve metabolic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, learning or memory, neurotrophin TRK receptor signaling pathway, protein phosphorylation, regulation of insulin secretion, signal transduction, small molecule metabolic process, transmembrane transport, water transport cAMP-dependent protein kinase complex, cytosol, plasma membrane cAMP binding, cAMP-dependent protein kinase regulator activity Human PRKAR2A UniProtKB UniProtKB {GO:0005886=PMID:21423175, GO:0008603=GO_REF:0000002, GO:0007202=Reactome:REACT_12079, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_24992, GO:0035556=PMID:2540040, GO:0005737=PMID:21423175, GO:0030552=GO_REF:0000037, GO:0007173=Reactome:REACT_9417, GO:0071377=Reactome:REACT_1665, GO:0016301=GO_REF:0000038, GO:0006833=Reactome:REACT_24023, GO:0034199=Reactome:REACT_15530, GO:0031625=PMID:21423175, GO:0005813=PMID:21399614, GO:0005952=GO_REF:0000002, GO:0048011=Reactome:REACT_11061, GO:0055085=Reactome:REACT_15518, GO:0007165=GO_REF:0000002, GO:0006112=Reactome:REACT_1505, GO:0016020=PMID:10799517, GO:0050796=Reactome:REACT_18325, GO:0007596=Reactome:REACT_604, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802} Q9BUB1 Protein kinase, cAMP-dependent, regulatory, type II, alpha protein 20130413 {GO:0005886=IDA, GO:0008603=IEA, GO:0007202=TAS, GO:0044281=TAS, GO:0005829=TAS, GO:0035556=TAS, GO:0005737=IDA, GO:0030552=IEA, GO:0007173=TAS, GO:0071377=TAS, GO:0016301=IEA, GO:0006833=TAS, GO:0034199=TAS, GO:0031625=IDA, GO:0005813=IDA, GO:0005952=IEA, GO:0048011=TAS, GO:0055085=TAS, GO:0007165=IEA, GO:0006112=TAS, GO:0016020=TAS, GO:0050796=TAS, GO:0007596=TAS, GO:0008543=TAS, GO:0045087=TAS} activation of phospholipase C activity, activation of protein kinase A activity, blood coagulation, cellular response to glucagon stimulus, energy reserve metabolic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, regulation of insulin secretion, signal transduction, small molecule metabolic process, transmembrane transport, water transport cAMP-dependent protein kinase complex, centrosome, cytoplasm, cytosol, membrane, plasma membrane cAMP binding, cAMP-dependent protein kinase regulator activity, kinase activity, ubiquitin protein ligase binding Human UniProtKB-KW:KW-0418 PRKAR2B Reactome UniProtKB {GO:0048471=GO_REF:0000019, GO:0005886=PMID:21423175, GO:0008603=GO_REF:0000019, GO:0005743=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0007202=Reactome:REACT_12079, GO:0005829=Reactome:REACT_24992, GO:0035556=PMID:2851102, GO:0005737=PMID:21423175, GO:0030552=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0071377=Reactome:REACT_1665, GO:0000086=Reactome:REACT_2203, GO:0006631=GO_REF:0000019, GO:0007612=GO_REF:0000019, GO:0006833=Reactome:REACT_24023, GO:0034199=Reactome:REACT_15530, GO:0031625=PMID:21423175, GO:0048011=Reactome:REACT_11061, GO:0005952=GO_REF:0000019, GO:0005813=PMID:21399614, GO:0097332=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0097338=GO_REF:0000019, GO:0007165=Reactome:REACT_12478, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0008543=Reactome:REACT_9470, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0045121=GO_REF:0000019, GO:0000278=Reactome:REACT_152} P31323 cAMP-dependent protein kinase type II-beta regulatory subunit protein 20130301 {GO:0048471=IEA, GO:0005886=IDA, GO:0008603=IEA, GO:0005743=IEA, GO:0044281=TAS, GO:0007202=TAS, GO:0005829=TAS, GO:0035556=TAS, GO:0005737=IDA, GO:0030552=IEA, GO:0007173=TAS, GO:0071377=TAS, GO:0000086=TAS, GO:0006631=IEA, GO:0007612=IEA, GO:0006833=TAS, GO:0034199=TAS, GO:0031625=IDA, GO:0048011=TAS, GO:0005952=IEA, GO:0005813=IDA, GO:0097332=IEA, GO:0019904=IEA, GO:0055085=TAS, GO:0097338=IEA, GO:0007165=TAS, GO:0006112=TAS, GO:0050796=TAS, GO:0008543=TAS, GO:0007596=TAS, GO:0045087=TAS, GO:0045121=IEA, GO:0000278=TAS} G2/M transition of mitotic cell cycle, activation of phospholipase C activity, activation of protein kinase A activity, blood coagulation, cellular response to glucagon stimulus, energy reserve metabolic process, epidermal growth factor receptor signaling pathway, fatty acid metabolic process, fibroblast growth factor receptor signaling pathway, innate immune response, intracellular signal transduction, learning, mitotic cell cycle, neurotrophin TRK receptor signaling pathway, regulation of insulin secretion, response to antipsychotic drug, response to clozapine, signal transduction, small molecule metabolic process, transmembrane transport, water transport cAMP-dependent protein kinase complex, centrosome, cytoplasm, cytosol, membrane raft, mitochondrial inner membrane, perinuclear region of cytoplasm, plasma membrane cAMP binding, cAMP-dependent protein kinase regulator activity, protein domain specific binding, ubiquitin protein ligase binding Human PRKCA BHF-UCL UniProtKB {GO:0005515=PMID:21703451, GO:0010467=Reactome:REACT_71, GO:0050730=GO_REF:0000019, GO:0006937=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0002062=GO_REF:0000019, GO:0046325=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0031666=PMID:9830023, GO:0002159=PMID:18474624, GO:0070374=GO_REF:0000024, GO:0031966=GO_REF:0000039, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0030593=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0045651=GO_REF:0000024, GO:0045785=PMID:11909826, GO:0050930=GO_REF:0000019, GO:0010595=PMID:11909826, GO:0043536=PMID:20011604, GO:0045931=PMID:10848585, GO:0008543=Reactome:REACT_9470, GO:0002026=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0005654=Reactome:REACT_25016, GO:0008270=GO_REF:0000002, GO:0004698=GO_REF:0000019, GO:0004697=GO_REF:0000024, GO:0019899=PMID:18556656, GO:0001750=GO_REF:0000019, GO:0048471=GO_REF:0000024, GO:0008285=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0005783=PMID:18556656, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0007202=Reactome:REACT_12079, GO:0007194=GO_REF:0000024, GO:0030425=GO_REF:0000019, GO:0046872=GO_REF:0000038, GO:0005829=Reactome:REACT_111196, GO:0035556=GO_REF:0000002, GO:0000188=GO_REF:0000019, GO:0007190=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0007155=GO_REF:0000037, GO:0070555=PMID:19281832, GO:0010613=GO_REF:0000024, GO:2000707=GO_REF:0000024, GO:0048011=Reactome:REACT_11061, GO:0035408=PMID:20228790, GO:0046627=GO_REF:0000019, GO:0090330=PMID:12724315, GO:0006874=GO_REF:0000019, GO:0001525=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0097190=PMID:10825394, GO:0097193=GO_REF:0000019, GO:0045766=PMID:11909826, GO:0035403=PMID:20228790, GO:0007165=Reactome:REACT_12478, GO:0006112=Reactome:REACT_1505, GO:0004672=PMID:10770950, GO:0050796=Reactome:REACT_18325, GO:0001938=PMID:11909826, GO:0007596=Reactome:REACT_604, GO:0004674=Reactome:REACT_18263, GO:0050729=GO_REF:0000019, GO:0001934=GO_REF:0000019, GO:0034351=PMID:9927633, GO:0006468=PMID:10770950, GO:0071322=GO_REF:0000019} P17252 Protein kinase C alpha type protein 20120928 {GO:0005515=IPI, GO:0010467=TAS, GO:0050730=IEA, GO:0006937=IEA, GO:0007173=TAS, GO:0002062=IEA, GO:0046325=IEA, GO:0043025=IEA, GO:0031666=IMP, GO:0002159=IMP, GO:0070374=ISS, GO:0031966=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0030593=IEA, GO:0030168=TAS, GO:0045651=ISS, GO:0045785=IMP, GO:0050930=IEA, GO:0010595=IMP, GO:0043536=IDA, GO:0045931=IMP, GO:0008543=TAS, GO:0002026=IEA, GO:0045087=TAS, GO:0005654=TAS, GO:0008270=IEA, GO:0004698=IEA, GO:0004697=ISS, GO:0019899=IPI, GO:0001750=IEA, GO:0048471=ISS, GO:0008285=IEA, GO:0005886=IDA, GO:0005783=IDA, GO:0007268=TAS, GO:0044281=TAS, GO:0007202=TAS, GO:0007194=ISS, GO:0030425=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0035556=IEA, GO:0000188=IEA, GO:0007190=ISS, GO:0005737=IDA, GO:0007155=IEA, GO:0070555=IMP, GO:0010613=ISS, GO:2000707=ISS, GO:0048011=TAS, GO:0035408=IDA, GO:0046627=IEA, GO:0090330=IDA, GO:0006874=IEA, GO:0001525=IEA, GO:0005524=IEA, GO:0097190=TAS, GO:0097193=IEA, GO:0045766=IMP, GO:0035403=IDA, GO:0007165=TAS, GO:0006112=TAS, GO:0004672=IDA, GO:0050796=TAS, GO:0001938=IMP, GO:0007596=TAS, GO:0004674=TAS, GO:0050729=IEA, GO:0001934=IEA, GO:0034351=IMP, GO:0006468=IDA, GO:0071322=IEA} RNA metabolic process, activation of adenylate cyclase activity, activation of phospholipase C activity, angiogenesis, apoptotic signaling pathway, blood coagulation, cell adhesion, cellular calcium ion homeostasis, cellular response to carbohydrate stimulus, chondrocyte differentiation, desmosome assembly, energy reserve metabolic process, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, gene expression, histone H3-T6 phosphorylation, inactivation of MAPK activity, induction of positive chemotaxis, innate immune response, intracellular signal transduction, intrinsic apoptotic signaling pathway, mRNA metabolic process, negative regulation of adenylate cyclase activity, negative regulation of cell proliferation, negative regulation of glial cell apoptotic process, negative regulation of glucose import, negative regulation of insulin receptor signaling pathway, neurotrophin TRK receptor signaling pathway, neutrophil chemotaxis, platelet activation, positive regulation of ERK1 and ERK2 cascade, positive regulation of angiogenesis, positive regulation of blood vessel endothelial cell migration, positive regulation of cardiac muscle hypertrophy, positive regulation of cell adhesion, positive regulation of dense core granule biogenesis, positive regulation of endothelial cell migration, positive regulation of endothelial cell proliferation, positive regulation of inflammatory response, positive regulation of lipopolysaccharide-mediated signaling pathway, positive regulation of macrophage differentiation, positive regulation of mitotic cell cycle, positive regulation of protein phosphorylation, protein phosphorylation, regulation of insulin secretion, regulation of muscle contraction, regulation of peptidyl-tyrosine phosphorylation, regulation of platelet aggregation, regulation of the force of heart contraction, response to interleukin-1, signal transduction, small molecule metabolic process, synaptic transmission cytoplasm, cytosol, dendrite, endoplasmic reticulum, mitochondrial membrane, neuronal cell body, nucleoplasm, perinuclear region of cytoplasm, photoreceptor outer segment, plasma membrane ATP binding, calcium-dependent protein kinase C activity, enzyme binding, histone kinase activity (H3-T6 specific), metal ion binding, protein binding, protein kinase C activity, protein kinase activity, protein serine/threonine kinase activity, zinc ion binding Human PRKCB BHF-UCL UniProtKB {GO:0005515=PMID:20228790, GO:0050853=GO_REF:0000024, GO:0030949=GO_REF:0000024, GO:0005886=Reactome:REACT_118748, GO:0007268=Reactome:REACT_13685, GO:0005634=PMID:20228790, GO:0050681=PMID:20228790, GO:0005829=Reactome:REACT_118748, GO:0035556=GO_REF:0000002, GO:0042393=PMID:20228790, GO:0042953=PMID:18981301, GO:0005737=PMID:15632189, GO:0030374=PMID:20228790, GO:0051092=GO_REF:0000024, GO:0005080=PMID:20228790, GO:0006816=GO_REF:0000019, GO:0043123=GO_REF:0000024, GO:0035408=PMID:20228790, GO:0006357=PMID:20228790, GO:0005246=GO_REF:0000019, GO:0046627=GO_REF:0000024, GO:0006874=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0006915=GO_REF:0000037, GO:0010829=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0050861=GO_REF:0000024, GO:0045766=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0035403=PMID:20228790, GO:0007165=PMID:3755548, GO:0042113=GO_REF:0000024, GO:0007596=Reactome:REACT_604, GO:0004674=Reactome:REACT_118598, GO:0003682=PMID:20228790, GO:0006468=PMID:3755548, GO:0008270=GO_REF:0000002, GO:0004697=GO_REF:0000003, GO:0071322=GO_REF:0000019} P05771 Protein kinase C beta type protein 20090115 {GO:0005515=IPI, GO:0050853=ISS, GO:0030949=ISS, GO:0005886=TAS, GO:0007268=TAS, GO:0005634=IDA, GO:0050681=IDA, GO:0005829=TAS, GO:0035556=IEA, GO:0042393=IDA, GO:0042953=TAS, GO:0005737=IDA, GO:0030374=IMP, GO:0051092=ISS, GO:0005080=IPI, GO:0006816=IEA, GO:0043123=ISS, GO:0035408=IDA, GO:0006357=IMP, GO:0005246=IEA, GO:0046627=ISS, GO:0006874=IEA, GO:0030168=TAS, GO:0006915=IEA, GO:0010829=ISS, GO:0005524=IEA, GO:0050861=ISS, GO:0045766=ISS, GO:0006351=IEA, GO:0035403=IDA, GO:0007165=NAS, GO:0042113=ISS, GO:0007596=TAS, GO:0004674=TAS, GO:0003682=IDA, GO:0006468=TAS, GO:0008270=IEA, GO:0004697=IEA, GO:0071322=IEA} B cell activation, B cell receptor signaling pathway, apoptotic process, blood coagulation, calcium ion transport, cellular calcium ion homeostasis, cellular response to carbohydrate stimulus, histone H3-T6 phosphorylation, intracellular signal transduction, lipoprotein transport, negative regulation of glucose transport, negative regulation of insulin receptor signaling pathway, platelet activation, positive regulation of B cell receptor signaling pathway, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of angiogenesis, positive regulation of vascular endothelial growth factor receptor signaling pathway, protein phosphorylation, regulation of transcription from RNA polymerase II promoter, signal transduction, synaptic transmission, transcription, DNA-dependent cytoplasm, cytosol, nucleus, plasma membrane ATP binding, androgen receptor binding, calcium channel regulator activity, chromatin binding, histone binding, histone kinase activity (H3-T6 specific), ligand-dependent nuclear receptor transcription coactivator activity, protein binding, protein kinase C activity, protein kinase C binding, protein serine/threonine kinase activity, zinc ion binding Human PRKCD HPA UniProtKB {GO:0005515=PMID:12721299, GO:0010467=Reactome:REACT_71, GO:0014070=GO_REF:0000019, GO:0042542=GO_REF:0000019, GO:0010469=PMID:14583092, GO:0016064=GO_REF:0000019, GO:0009408=GO_REF:0000019, GO:0019221=Reactome:REACT_25229, GO:0050732=PMID:14583092, GO:0043560=GO_REF:0000024, GO:0051490=GO_REF:0000024, GO:0046777=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0015810=GO_REF:0000019, GO:1900163=PMID:10770950, GO:0046326=GO_REF:0000019, GO:0018107=PMID:10770950, GO:0030837=GO_REF:0000024, GO:2000755=PMID:19279011, GO:0042742=GO_REF:0000024, GO:2000753=PMID:19279011, GO:0060333=Reactome:REACT_25078, GO:0032869=GO_REF:0000019, GO:0016070=Reactome:REACT_21257, GO:0019901=GO_REF:0000019, GO:0016071=Reactome:REACT_20605, GO:0007568=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0007049=GO_REF:0000037, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0032963=GO_REF:0000019, GO:0005654=Reactome:REACT_25202, GO:0004697=GO_REF:0000024, GO:0042119=PMID:10770950, GO:0019899=PMID:18556656, GO:0008047=PMID:16611985, GO:0023021=PMID:19279008, GO:0038096=Reactome:REACT_160123, GO:0090398=PMID:15282327, GO:0032091=PMID:14583092, GO:0004699=PMID:14583092, GO:0048471=GO_REF:0000039, GO:0005886=Reactome:REACT_12062, GO:0005783=PMID:18556656, GO:0045471=GO_REF:0000019, GO:0005634=PMID:15774464, GO:0007202=Reactome:REACT_12079, GO:0016363=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_25369, GO:0035556=GO_REF:0000019, GO:0005739=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0005911=GO_REF:0000019, GO:0043406=GO_REF:0000019, GO:0042100=GO_REF:0000019, GO:0043407=PMID:19279008, GO:0042149=GO_REF:0000019, GO:0043200=GO_REF:0000019, GO:0032930=PMID:19801500, GO:0001666=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:2000304=PMID:19279011, GO:0035307=PMID:19279008, GO:0042493=GO_REF:0000019, GO:0046627=PMID:14583092, GO:0050821=PMID:16611985, GO:0070976=GO_REF:0000019, GO:0090331=GO_REF:0000024, GO:0006915=Reactome:REACT_578, GO:0006917=GO_REF:0000019, GO:0008022=PMID:16611985, GO:0005524=GO_REF:0000037, GO:0009749=GO_REF:0000019, GO:0009612=GO_REF:0000019, GO:0007165=Reactome:REACT_12478, GO:0032615=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0004674=PMID:10770950, GO:0050728=PMID:19279008, GO:0034351=PMID:15774464, GO:0006468=PMID:16611985, GO:0032613=GO_REF:0000019, GO:0004715=GO_REF:0000003} Q05655 Protein kinase C delta type protein 20080205 {GO:0005515=IPI, GO:0010467=TAS, GO:0014070=IEA, GO:0042542=IEA, GO:0010469=TAS, GO:0016064=IEA, GO:0009408=IEA, GO:0019221=TAS, GO:0050732=ISS, GO:0043560=ISS, GO:0051490=ISS, GO:0046777=IEA, GO:0007173=TAS, GO:0015810=IEA, GO:1900163=IMP, GO:0046326=IEA, GO:0018107=IDA, GO:0030837=ISS, GO:2000755=IMP, GO:0042742=ISS, GO:2000753=IMP, GO:0060333=TAS, GO:0032869=IEA, GO:0016070=TAS, GO:0019901=IEA, GO:0016071=TAS, GO:0007568=IEA, GO:0030168=TAS, GO:0007049=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:0032963=IEA, GO:0005654=TAS, GO:0004697=ISS, GO:0042119=IDA, GO:0019899=IPI, GO:0008047=IDA, GO:0023021=IMP, GO:0038096=TAS, GO:0090398=IMP, GO:0032091=TAS, GO:0004699=TAS, GO:0048471=IEA, GO:0005886=TAS, GO:0005783=IDA, GO:0045471=IEA, GO:0005634=IDA, GO:0007202=TAS, GO:0016363=IEA, GO:0046872=IEA, GO:0006921=TAS, GO:0005829=TAS, GO:0035556=IEA, GO:0005739=IEA, GO:0005737=IDA, GO:0005911=IEA, GO:0043406=IEA, GO:0042100=IEA, GO:0043407=IMP, GO:0042149=IEA, GO:0043200=IEA, GO:0032930=IMP, GO:0001666=IEA, GO:0048011=TAS, GO:2000304=IMP, GO:0035307=IMP, GO:0042493=IEA, GO:0046627=TAS, GO:0050821=NAS, GO:0070976=IEA, GO:0090331=ISS, GO:0006915=TAS, GO:0006917=IEA, GO:0008022=IPI, GO:0005524=IEA, GO:0009749=IEA, GO:0009612=IEA, GO:0007165=TAS, GO:0032615=IEA, GO:0007596=TAS, GO:0004674=IDA, GO:0050728=IC, GO:0034351=IMP, GO:0006468=IDA, GO:0032613=IEA, GO:0004715=IEA} B cell proliferation, Fc-gamma receptor signaling pathway involved in phagocytosis, RNA metabolic process, activation of phospholipase C activity, aging, apoptotic process, aspartate transport, blood coagulation, cell cycle, cellular component disassembly involved in execution phase of apoptosis, cellular response to glucose starvation, cellular response to insulin stimulus, cellular senescence, collagen metabolic process, cytokine-mediated signaling pathway, defense response to bacterium, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, gene expression, immunoglobulin mediated immune response, induction of apoptosis, innate immune response, interferon-gamma-mediated signaling pathway, interleukin-10 production, interleukin-12 production, intracellular signal transduction, mRNA metabolic process, negative regulation of MAP kinase activity, negative regulation of actin filament polymerization, negative regulation of filopodium assembly, negative regulation of glial cell apoptotic process, negative regulation of inflammatory response, negative regulation of insulin receptor signaling pathway, negative regulation of peptidyl-tyrosine phosphorylation, negative regulation of platelet aggregation, negative regulation of protein binding, neurotrophin TRK receptor signaling pathway, neutrophil activation, peptidyl-threonine phosphorylation, platelet activation, positive regulation of MAP kinase activity, positive regulation of ceramide biosynthetic process, positive regulation of glucose import, positive regulation of glucosylceramide catabolic process, positive regulation of phospholipid scramblase activity, positive regulation of protein dephosphorylation, positive regulation of sphingomyelin catabolic process, positive regulation of superoxide anion generation, protein autophosphorylation, protein phosphorylation, protein stabilization, regulation of receptor activity, response to amino acid stimulus, response to drug, response to ethanol, response to glucose stimulus, response to heat, response to hydrogen peroxide, response to hypoxia, response to mechanical stimulus, response to organic cyclic compound, signal transduction, termination of signal transduction cell-cell junction, cytoplasm, cytosol, endoplasmic reticulum, mitochondrion, nuclear matrix, nucleoplasm, nucleus, perinuclear region of cytoplasm, plasma membrane ATP binding, TIR domain binding, calcium-independent protein kinase C activity, enzyme activator activity, enzyme binding, insulin receptor substrate binding, metal ion binding, non-membrane spanning protein tyrosine kinase activity, protein C-terminus binding, protein binding, protein kinase C activity, protein kinase binding, protein serine/threonine kinase activity Human PRKCDBP ENSEMBL UniProtKB {GO:0005080=GO_REF:0000019} Q969G5 Protein kinase C delta-binding protein protein 20130413 {GO:0005080=IEA} protein kinase C binding Human Ensembl:ENSRNOP00000024119 PRKCE BHF-UCL UniProtKB {GO:0005515=PMID:22939624, GO:0050730=GO_REF:0000019, GO:0010763=GO_REF:0000024, GO:0030838=GO_REF:0000024, GO:0007173=Reactome:REACT_9417, GO:0032024=GO_REF:0000019, GO:0043123=GO_REF:0000019, GO:0005856=GO_REF:0000039, GO:0031663=GO_REF:0000024, GO:0035641=GO_REF:0000019, GO:0051209=GO_REF:0000019, GO:0005794=GO_REF:0000024, GO:0030168=Reactome:REACT_798, GO:0043278=GO_REF:0000019, GO:0032230=GO_REF:0000019, GO:0007049=GO_REF:0000037, GO:0035276=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0030546=GO_REF:0000019, GO:0004697=PMID:18556656, GO:0008047=PMID:18556656, GO:0019899=PMID:18556656, GO:0038096=Reactome:REACT_160123, GO:0035669=GO_REF:0000024, GO:0051301=GO_REF:0000037, GO:0050996=GO_REF:0000019, GO:0048471=GO_REF:0000024, GO:0004699=GO_REF:0000019, GO:0005886=Reactome:REACT_12062, GO:0005783=PMID:18556656, GO:0090303=PMID:17603037, GO:0010811=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0007202=Reactome:REACT_12079, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_23917, GO:0070257=GO_REF:0000019, GO:0071944=GO_REF:0000024, GO:0005739=GO_REF:0000019, GO:0035556=GO_REF:0000002, GO:0071889=GO_REF:0000019, GO:0005737=PMID:15632189, GO:0002281=GO_REF:0000019, GO:0004871=PMID:1382605, GO:0007155=GO_REF:0000037, GO:0048011=Reactome:REACT_11061, GO:2001031=PMID:18556656, GO:0071456=GO_REF:0000019, GO:0006917=PMID:10438519, GO:0005524=GO_REF:0000037, GO:0003785=GO_REF:0000024, GO:0007165=Reactome:REACT_12478, GO:0071361=GO_REF:0000019, GO:0004672=GO_REF:0000002, GO:0016020=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0006468=PMID:18556656, GO:0043410=GO_REF:0000019, GO:0010634=PMID:17603037, GO:0061178=GO_REF:0000019} Q02156 Protein kinase C epsilon type protein 20120404 {GO:0005515=IPI, GO:0050730=IEA, GO:0010763=ISS, GO:0030838=ISS, GO:0007173=TAS, GO:0032024=IEA, GO:0043123=IEA, GO:0005856=IEA, GO:0031663=ISS, GO:0035641=IEA, GO:0051209=IEA, GO:0005794=ISS, GO:0030168=TAS, GO:0043278=IEA, GO:0032230=IEA, GO:0007049=IEA, GO:0035276=IEA, GO:0008543=TAS, GO:0045087=TAS, GO:0030546=IEA, GO:0004697=IDA, GO:0008047=IMP, GO:0019899=IPI, GO:0038096=TAS, GO:0035669=ISS, GO:0051301=IEA, GO:0050996=IEA, GO:0048471=ISS, GO:0004699=IEA, GO:0005886=TAS, GO:0005783=IDA, GO:0090303=IMP, GO:0010811=IEA, GO:0005634=IEA, GO:0007202=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0070257=IEA, GO:0071944=ISS, GO:0005739=IEA, GO:0035556=IEA, GO:0071889=IEA, GO:0005737=IDA, GO:0002281=IEA, GO:0004871=TAS, GO:0007155=IEA, GO:0048011=TAS, GO:2001031=IMP, GO:0071456=IEA, GO:0006917=TAS, GO:0005524=IEA, GO:0003785=ISS, GO:0007165=TAS, GO:0071361=IEA, GO:0004672=IEA, GO:0016020=IEA, GO:0007596=TAS, GO:0006468=IDA, GO:0043410=IEA, GO:0010634=IMP, GO:0061178=IEA} Fc-gamma receptor signaling pathway involved in phagocytosis, TRAM-dependent toll-like receptor 4 signaling pathway, activation of phospholipase C activity, blood coagulation, cell adhesion, cell cycle, cell division, cellular response to ethanol, cellular response to hypoxia, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, induction of apoptosis, innate immune response, intracellular signal transduction, lipopolysaccharide-mediated signaling pathway, locomotory exploration behavior, macrophage activation involved in immune response, neurotrophin TRK receptor signaling pathway, platelet activation, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of MAPK cascade, positive regulation of actin filament polymerization, positive regulation of cell-substrate adhesion, positive regulation of cellular glucuronidation, positive regulation of epithelial cell migration, positive regulation of fibroblast migration, positive regulation of insulin secretion, positive regulation of lipid catabolic process, positive regulation of mucus secretion, positive regulation of synaptic transmission, GABAergic, positive regulation of wound healing, protein phosphorylation, regulation of insulin secretion involved in cellular response to glucose stimulus, regulation of peptidyl-tyrosine phosphorylation, release of sequestered calcium ion into cytosol, response to morphine, signal transduction Golgi apparatus, cell periphery, cytoplasm, cytoskeleton, cytosol, endoplasmic reticulum, membrane, mitochondrion, nucleus, perinuclear region of cytoplasm, plasma membrane 14-3-3 protein binding, ATP binding, actin monomer binding, calcium-independent protein kinase C activity, enzyme activator activity, enzyme binding, ethanol binding, metal ion binding, protein binding, protein kinase C activity, protein kinase activity, receptor activator activity, signal transducer activity Human PRKCG Reactome UniProtKB {GO:0008219=GO_REF:0000037, GO:0048471=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000024, GO:0007635=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0005634=GO_REF:0000019, GO:0007202=Reactome:REACT_12079, GO:0046872=GO_REF:0000038, GO:0030425=GO_REF:0000024, GO:0005829=Reactome:REACT_18330, GO:0035556=GO_REF:0000002, GO:0043524=GO_REF:0000024, GO:0046777=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0016301=GO_REF:0000038, GO:0007611=GO_REF:0000019, GO:0031397=PMID:15808853, GO:0048011=Reactome:REACT_11061, GO:0042177=PMID:15808853, GO:0030168=Reactome:REACT_798, GO:0043278=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0032425=PMID:15808853, GO:0060384=GO_REF:0000019, GO:0007165=Reactome:REACT_12478, GO:0016310=PMID:15808853, GO:0004672=PMID:15808853, GO:0008543=Reactome:REACT_9470, GO:0007596=Reactome:REACT_604, GO:0004674=GO_REF:0000038, GO:0045087=Reactome:REACT_6802, GO:0097060=GO_REF:0000019, GO:0006468=PMID:3755548, GO:0048265=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0004698=GO_REF:0000019, GO:0004697=PMID:3755548} P05129 Protein kinase C gamma type protein 20130301 {GO:0008219=IEA, GO:0048471=ISS, GO:0030054=IEA, GO:0005886=ISS, GO:0007635=IEA, GO:0007268=TAS, GO:0005634=IEA, GO:0007202=TAS, GO:0046872=IEA, GO:0030425=ISS, GO:0005829=TAS, GO:0035556=IEA, GO:0043524=ISS, GO:0046777=IEA, GO:0007173=TAS, GO:0016301=IEA, GO:0007611=IEA, GO:0031397=IDA, GO:0048011=TAS, GO:0042177=IDA, GO:0030168=TAS, GO:0043278=ISS, GO:0005524=IEA, GO:0032425=IDA, GO:0060384=IEA, GO:0007165=TAS, GO:0016310=IDA, GO:0004672=IDA, GO:0008543=TAS, GO:0007596=TAS, GO:0004674=IEA, GO:0045087=TAS, GO:0097060=IEA, GO:0006468=TAS, GO:0048265=ISS, GO:0008270=IEA, GO:0004698=IEA, GO:0004697=TAS} activation of phospholipase C activity, blood coagulation, cell death, chemosensory behavior, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, innervation, intracellular signal transduction, learning or memory, negative regulation of neuron apoptotic process, negative regulation of protein catabolic process, negative regulation of protein ubiquitination, neurotrophin TRK receptor signaling pathway, phosphorylation, platelet activation, positive regulation of mismatch repair, protein autophosphorylation, protein phosphorylation, response to morphine, response to pain, signal transduction, synaptic transmission cell junction, cytosol, dendrite, nucleus, perinuclear region of cytoplasm, plasma membrane, synaptic membrane ATP binding, calcium-dependent protein kinase C activity, kinase activity, metal ion binding, protein kinase C activity, protein kinase activity, protein serine/threonine kinase activity, zinc ion binding Human PRKCH Reactome UniProtKB {GO:0004699=GO_REF:0000019, GO:2000810=PMID:19114660, GO:0005886=PMID:15632189, GO:0010744=GO_REF:0000024, GO:0030168=Reactome:REACT_798, GO:0060252=PMID:10806212, GO:0050861=PMID:18780722, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0070528=GO_REF:0000019, GO:0005829=Reactome:REACT_23917, GO:0035556=GO_REF:0000002, GO:0007165=PMID:1986216, GO:0005737=PMID:15632189, GO:0051092=PMID:21820409, GO:0045618=GO_REF:0000024, GO:0007596=Reactome:REACT_604, GO:0034351=PMID:11772428, GO:0006468=PMID:1986216, GO:0004697=PMID:1986216, GO:0019899=PMID:15632189, GO:0017160=GO_REF:0000019} P24723 Protein kinase C eta type protein 20130213 {GO:0004699=IEA, GO:2000810=IMP, GO:0005886=IDA, GO:0010744=ISS, GO:0030168=TAS, GO:0060252=IMP, GO:0050861=IMP, GO:0005524=IEA, GO:0046872=IEA, GO:0070528=IEA, GO:0005829=TAS, GO:0035556=IEA, GO:0007165=TAS, GO:0005737=IDA, GO:0051092=IMP, GO:0045618=ISS, GO:0007596=TAS, GO:0034351=IMP, GO:0006468=TAS, GO:0004697=TAS, GO:0019899=IPI, GO:0017160=IEA} blood coagulation, intracellular signal transduction, negative regulation of glial cell apoptotic process, platelet activation, positive regulation of B cell receptor signaling pathway, positive regulation of NF-kappaB transcription factor activity, positive regulation of glial cell proliferation, positive regulation of keratinocyte differentiation, positive regulation of macrophage derived foam cell differentiation, protein kinase C signaling cascade, protein phosphorylation, regulation of tight junction assembly, signal transduction cytoplasm, cytosol, plasma membrane ATP binding, Ral GTPase binding, calcium-independent protein kinase C activity, enzyme binding, metal ion binding, protein kinase C activity Human PRKCI BHF-UCL UniProtKB {GO:0005515=PMID:17979178, GO:0005886=Reactome:REACT_19353, GO:0035089=GO_REF:0000019, GO:0000133=PMID:14676191, GO:0005634=PMID:21419810, GO:0005829=Reactome:REACT_19353, GO:0035556=GO_REF:0000002, GO:0043524=PMID:10467349, GO:0016324=GO_REF:0000019, GO:0051092=PMID:10467349, GO:0005543=PMID:8226978, GO:0070830=Reactome:REACT_19373, GO:0046326=GO_REF:0000024, GO:0006612=PMID:11257119, GO:0007010=PMID:11257119, GO:0007015=GO_REF:0000019, GO:0016192=PMID:11257119, GO:0031252=GO_REF:0000019, GO:0070555=GO_REF:0000019, GO:0043220=GO_REF:0000019, GO:0032869=GO_REF:0000024, GO:0048011=Reactome:REACT_13776, GO:0043066=Reactome:REACT_13537, GO:0034329=Reactome:REACT_20676, GO:0019904=GO_REF:0000019, GO:0060252=PMID:21419810, GO:0005524=PMID:8226978, GO:0046903=PMID:8226978, GO:0045216=Reactome:REACT_19331, GO:0045197=PMID:14676191, GO:0004672=PMID:11724794, GO:0016477=GO_REF:0000019, GO:0004674=Reactome:REACT_13726, GO:0010976=PMID:10467349, GO:0034351=PMID:21419810, GO:0048194=GO_REF:0000019, GO:0006468=PMID:8226978, GO:0008270=GO_REF:0000002, GO:0004697=GO_REF:0000024, GO:2000353=PMID:19327373, GO:0042462=GO_REF:0000019, GO:0016044=PMID:11257119, GO:0090004=GO_REF:0000024, GO:0005768=GO_REF:0000039} P41743 Protein kinase C iota type protein 20090219 {GO:0005515=IPI, GO:0005886=TAS, GO:0035089=IEA, GO:0000133=TAS, GO:0005634=IDA, GO:0005829=TAS, GO:0035556=IEA, GO:0043524=IDA, GO:0016324=IEA, GO:0051092=IDA, GO:0005543=IDA, GO:0070830=TAS, GO:0046326=ISS, GO:0006612=NAS, GO:0007010=NAS, GO:0007015=IEA, GO:0016192=TAS, GO:0031252=IEA, GO:0070555=IEA, GO:0043220=IEA, GO:0032869=ISS, GO:0048011=TAS, GO:0043066=TAS, GO:0034329=TAS, GO:0019904=IEA, GO:0060252=IMP, GO:0005524=TAS, GO:0046903=NAS, GO:0045216=TAS, GO:0045197=TAS, GO:0004672=IDA, GO:0016477=IEA, GO:0004674=TAS, GO:0010976=IMP, GO:0034351=IMP, GO:0048194=IEA, GO:0006468=IDA, GO:0008270=IEA, GO:0004697=ISS, GO:2000353=IMP, GO:0042462=IEA, GO:0016044=NAS, GO:0090004=ISS, GO:0005768=IEA} Golgi vesicle budding, actin filament organization, cell junction assembly, cell migration, cell-cell junction organization, cellular membrane organization, cellular response to insulin stimulus, cytoskeleton organization, establishment of apical/basal cell polarity, establishment or maintenance of epithelial cell apical/basal polarity, eye photoreceptor cell development, intracellular signal transduction, negative regulation of apoptotic process, negative regulation of glial cell apoptotic process, negative regulation of neuron apoptotic process, neurotrophin TRK receptor signaling pathway, positive regulation of NF-kappaB transcription factor activity, positive regulation of endothelial cell apoptotic process, positive regulation of establishment of protein localization to plasma membrane, positive regulation of glial cell proliferation, positive regulation of glucose import, positive regulation of neuron projection development, protein phosphorylation, protein targeting to membrane, response to interleukin-1, secretion, tight junction assembly, vesicle-mediated transport Schmidt-Lanterman incisure, apical plasma membrane, cell leading edge, cytosol, endosome, nucleus, plasma membrane, polarisome ATP binding, phospholipid binding, protein binding, protein domain specific binding, protein kinase C activity, protein kinase activity, protein serine/threonine kinase activity, zinc ion binding Human UniProtKB:Q62074 PRKCQ BHF-UCL UniProtKB {GO:0005515=PMID:23352416, GO:2000318=GO_REF:0000024, GO:0050852=Reactome:REACT_12526, GO:0032753=GO_REF:0000024, GO:0005886=Reactome:REACT_22301, GO:0070233=PMID:16709830, GO:0001558=PMID:8444877, GO:0006921=Reactome:REACT_995, GO:0046872=GO_REF:0000037, GO:0042802=PMID:11788586, GO:0005829=Reactome:REACT_23917, GO:0005622=GO_REF:0000029, GO:0035556=PMID:7686153, GO:0006954=GO_REF:0000037, GO:0051092=PMID:16356855, GO:0007411=Reactome:REACT_18266, GO:0042102=GO_REF:0000019, GO:0006509=GO_REF:0000024, GO:0001772=GO_REF:0000019, GO:0006355=GO_REF:0000024, GO:0032740=GO_REF:0000024, GO:0046627=PMID:15364919, GO:0090330=GO_REF:0000024, GO:0030168=Reactome:REACT_798, GO:0006915=Reactome:REACT_578, GO:0005524=GO_REF:0000029, GO:0045086=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0004674=Reactome:REACT_12573, GO:0050870=GO_REF:0000024, GO:0006468=GO_REF:0000029, GO:0004697=GO_REF:0000003, GO:2000570=GO_REF:0000024} Q04759 Protein kinase C theta type protein 20081114 {GO:0005515=IPI, GO:2000318=ISS, GO:0050852=TAS, GO:0032753=ISS, GO:0005886=TAS, GO:0070233=IMP, GO:0001558=NAS, GO:0006921=TAS, GO:0046872=IEA, GO:0042802=IPI, GO:0005829=TAS, GO:0005622=NAS, GO:0035556=NAS, GO:0006954=IEA, GO:0051092=IDA, GO:0007411=TAS, GO:0042102=IEA, GO:0006509=ISS, GO:0001772=IEA, GO:0006355=ISS, GO:0032740=ISS, GO:0046627=IMP, GO:0090330=ISS, GO:0030168=TAS, GO:0006915=TAS, GO:0005524=NAS, GO:0045086=IEA, GO:0007596=TAS, GO:0004674=TAS, GO:0050870=ISS, GO:0006468=NAS, GO:0004697=IEA, GO:2000570=ISS} T cell receptor signaling pathway, apoptotic process, axon guidance, blood coagulation, cellular component disassembly involved in execution phase of apoptosis, inflammatory response, intracellular signal transduction, membrane protein ectodomain proteolysis, negative regulation of T cell apoptotic process, negative regulation of insulin receptor signaling pathway, platelet activation, positive regulation of NF-kappaB transcription factor activity, positive regulation of T cell activation, positive regulation of T cell proliferation, positive regulation of T-helper 17 type immune response, positive regulation of T-helper 2 cell activation, positive regulation of interleukin-17 production, positive regulation of interleukin-2 biosynthetic process, positive regulation of interleukin-4 production, protein phosphorylation, regulation of cell growth, regulation of platelet aggregation, regulation of transcription, DNA-dependent cytosol, immunological synapse, intracellular, plasma membrane ATP binding, identical protein binding, metal ion binding, protein binding, protein kinase C activity, protein serine/threonine kinase activity Human UniProtKB:Q02111 PRKCSH Reactome UniProtKB {GO:0003723=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0051291=GO_REF:0000019, GO:0007243=PMID:9043864, GO:0005622=PMID:2793184, GO:0006457=Reactome:REACT_23878, GO:0045087=Reactome:REACT_6802, GO:0006491=GO_REF:0000002, GO:0005080=PMID:15707389, GO:0010977=GO_REF:0000019, GO:0005788=Reactome:REACT_23850, GO:0044267=Reactome:REACT_17015, GO:0018279=Reactome:REACT_22426, GO:0043687=Reactome:REACT_22161} P14314 Glucosidase 2 subunit beta protein 20130301 {GO:0003723=IEA, GO:0005509=IEA, GO:0051291=IEA, GO:0007243=NAS, GO:0005622=NAS, GO:0006457=TAS, GO:0045087=TAS, GO:0006491=IEA, GO:0005080=IPI, GO:0010977=IEA, GO:0005788=TAS, GO:0044267=TAS, GO:0018279=TAS, GO:0043687=TAS} N-glycan processing, cellular protein metabolic process, innate immune response, intracellular protein kinase cascade, negative regulation of neuron projection development, post-translational protein modification, protein N-linked glycosylation via asparagine, protein folding, protein heterooligomerization endoplasmic reticulum lumen, intracellular RNA binding, calcium ion binding, protein kinase C binding Human PRKCZ BHF-UCL UniProtKB {GO:0005515=PMID:22939624, GO:2000553=GO_REF:0000024, GO:0032753=GO_REF:0000024, GO:0030054=Reactome:REACT_121319, GO:0050732=PMID:15069075, GO:0015459=GO_REF:0000019, GO:0043560=PMID:15069075, GO:0030010=GO_REF:0000024, GO:0060291=GO_REF:0000024, GO:0018105=PMID:15069075, GO:0043274=GO_REF:0000019, GO:0047496=GO_REF:0000019, GO:0046326=GO_REF:0000019, GO:0007179=Reactome:REACT_120726, GO:0070374=PMID:11035106, GO:0035748=GO_REF:0000019, GO:0031584=GO_REF:0000019, GO:2000664=GO_REF:0000024, GO:2000667=GO_REF:0000024, GO:0019901=GO_REF:0000019, GO:0007616=GO_REF:0000019, GO:0031532=GO_REF:0000019, GO:2000463=GO_REF:0000024, GO:0051346=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0043234=GO_REF:0000019, GO:0060081=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0045121=GO_REF:0000019, GO:0004697=GO_REF:0000003, GO:0005923=GO_REF:0000019, GO:0001954=GO_REF:0000019, GO:0008286=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:2001181=GO_REF:0000024, GO:0005886=PMID:7925449, GO:0005635=GO_REF:0000019, GO:0051291=GO_REF:0000019, GO:0016363=GO_REF:0000019, GO:0046872=GO_REF:0000038, GO:0005829=GO_REF:0000019, GO:0035556=GO_REF:0000002, GO:0071889=GO_REF:0000019, GO:0005737=PMID:7925449, GO:0016324=GO_REF:0000019, GO:0006954=GO_REF:0000037, GO:0051092=GO_REF:0000024, GO:0031333=PMID:15069075, GO:0045179=GO_REF:0000019, GO:0005911=PMID:20332120, GO:0032148=GO_REF:0000019, GO:0031252=GO_REF:0000019, GO:0045630=GO_REF:0000024, GO:0043066=GO_REF:0000019, GO:0046627=PMID:15069075, GO:0000226=GO_REF:0000019, GO:0046628=GO_REF:0000024, GO:0005524=GO_REF:0000019, GO:0072659=GO_REF:0000019, GO:0070528=GO_REF:0000019, GO:0007165=PMID:8224878, GO:0004672=PMID:10770950, GO:0016020=PMID:7925449, GO:0016477=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0004674=PMID:15069075, GO:0006468=PMID:10770950, GO:0005768=GO_REF:0000039} Q05513 Protein kinase C zeta type protein 20090216 {GO:0005515=IPI, GO:2000553=ISS, GO:0032753=ISS, GO:0030054=TAS, GO:0050732=IMP, GO:0015459=IEA, GO:0043560=IC, GO:0030010=ISS, GO:0060291=ISS, GO:0018105=IDA, GO:0043274=IEA, GO:0047496=IEA, GO:0046326=IEA, GO:0007179=TAS, GO:0070374=IMP, GO:0035748=IEA, GO:0031584=IEA, GO:2000664=ISS, GO:2000667=ISS, GO:0019901=IEA, GO:0007616=IEA, GO:0031532=IEA, GO:2000463=ISS, GO:0051346=IEA, GO:0019904=IEA, GO:0030168=TAS, GO:0043234=IEA, GO:0060081=IEA, GO:0008270=IEA, GO:0045121=IEA, GO:0004697=IEA, GO:0005923=IEA, GO:0001954=IEA, GO:0008286=IEA, GO:0008284=IEA, GO:0048471=IEA, GO:2001181=ISS, GO:0005886=TAS, GO:0005635=IEA, GO:0051291=IEA, GO:0016363=IEA, GO:0046872=IEA, GO:0005829=IEA, GO:0035556=IEA, GO:0071889=IEA, GO:0005737=TAS, GO:0016324=IEA, GO:0006954=IEA, GO:0051092=ISS, GO:0031333=IMP, GO:0045179=IEA, GO:0005911=IDA, GO:0032148=IEA, GO:0031252=IEA, GO:0045630=ISS, GO:0043066=IEA, GO:0046627=IMP, GO:0000226=IEA, GO:0046628=ISS, GO:0005524=IEA, GO:0072659=IEA, GO:0070528=IEA, GO:0007165=TAS, GO:0004672=IDA, GO:0016020=TAS, GO:0016477=IEA, GO:0007596=TAS, GO:0004674=IDA, GO:0006468=IDA, GO:0005768=IEA} actin cytoskeleton reorganization, activation of phospholipase D activity, activation of protein kinase B activity, blood coagulation, cell migration, establishment of cell polarity, inflammatory response, insulin receptor signaling pathway, intracellular signal transduction, long-term memory, long-term synaptic potentiation, membrane hyperpolarization, microtubule cytoskeleton organization, negative regulation of apoptotic process, negative regulation of hydrolase activity, negative regulation of insulin receptor signaling pathway, negative regulation of peptidyl-tyrosine phosphorylation, negative regulation of protein complex assembly, peptidyl-serine phosphorylation, platelet activation, positive regulation of ERK1 and ERK2 cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of T-helper 2 cell cytokine production, positive regulation of T-helper 2 cell differentiation, positive regulation of cell proliferation, positive regulation of cell-matrix adhesion, positive regulation of excitatory postsynaptic membrane potential, positive regulation of glucose import, positive regulation of insulin receptor signaling pathway, positive regulation of interleukin-10 secretion, positive regulation of interleukin-13 secretion, positive regulation of interleukin-4 production, positive regulation of interleukin-5 secretion, protein heterooligomerization, protein kinase C signaling cascade, protein localization to plasma membrane, protein phosphorylation, signal transduction, transforming growth factor beta receptor signaling pathway, vesicle transport along microtubule apical cortex, apical plasma membrane, cell junction, cell leading edge, cell-cell junction, cytoplasm, cytosol, endosome, membrane, membrane raft, myelin sheath abaxonal region, nuclear envelope, nuclear matrix, perinuclear region of cytoplasm, plasma membrane, protein complex, tight junction 14-3-3 protein binding, ATP binding, insulin receptor substrate binding, metal ion binding, phospholipase binding, potassium channel regulator activity, protein binding, protein domain specific binding, protein kinase C activity, protein kinase activity, protein kinase binding, protein serine/threonine kinase activity, zinc ion binding Human PRKD1 HPA UniProtKB {GO:0005515=PMID:22939624, GO:0005802=PMID:19211839, GO:0035924=PMID:18332134, GO:2001044=PMID:21488147, GO:0005886=GO_REF:0000052, GO:0008283=PMID:8119958, GO:0010837=GO_REF:0000024, GO:0005634=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0042802=PMID:19135240, GO:0005829=Reactome:REACT_19152, GO:0035556=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0046777=PMID:21488147, GO:0051092=PMID:12505989, GO:0006954=GO_REF:0000037, GO:0005543=GO_REF:0000002, GO:0005911=GO_REF:0000019, GO:0045806=PMID:21488147, GO:0007030=PMID:19211839, GO:0060548=PMID:12505989, GO:0043123=PMID:12505989, GO:0005938=GO_REF:0000019, GO:1901727=PMID:20497126, GO:0006665=Reactome:REACT_19323, GO:0005794=GO_REF:0000039, GO:0030148=Reactome:REACT_115810, GO:0006915=GO_REF:0000037, GO:0001525=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0045766=PMID:18332134, GO:0045669=GO_REF:0000024, GO:0010595=PMID:18332134, GO:0007165=PMID:8119958, GO:0007229=PMID:21488147, GO:0005887=PMID:8119958, GO:0004674=PMID:8119958, GO:0045087=GO_REF:0000037, GO:0010976=PMID:19211839, GO:0048193=GO_REF:0000024, GO:0004697=GO_REF:0000003, GO:0034599=PMID:12505989} Q15139 Serine/threonine-protein kinase D1 protein 20101115 {GO:0005515=IPI, GO:0005802=IDA, GO:0035924=IMP, GO:2001044=TAS, GO:0005886=IDA, GO:0008283=TAS, GO:0010837=ISS, GO:0005634=IEA, GO:0044281=TAS, GO:0046872=IEA, GO:0042802=IPI, GO:0005829=TAS, GO:0035556=IEA, GO:0005737=IDA, GO:0046777=TAS, GO:0051092=IMP, GO:0006954=IEA, GO:0005543=IEA, GO:0005911=IEA, GO:0045806=TAS, GO:0007030=IMP, GO:0060548=IMP, GO:0043123=IMP, GO:0005938=IEA, GO:1901727=IGI, GO:0006665=TAS, GO:0005794=IEA, GO:0030148=TAS, GO:0006915=IEA, GO:0001525=IEA, GO:0005524=IEA, GO:0045766=IMP, GO:0045669=ISS, GO:0010595=IMP, GO:0007165=TAS, GO:0007229=TAS, GO:0005887=TAS, GO:0004674=TAS, GO:0045087=IEA, GO:0010976=IMP, GO:0048193=ISS, GO:0004697=IEA, GO:0034599=IDA} Golgi organization, Golgi vesicle transport, angiogenesis, apoptotic process, cell proliferation, cellular response to oxidative stress, cellular response to vascular endothelial growth factor stimulus, inflammatory response, innate immune response, integrin-mediated signaling pathway, intracellular signal transduction, negative regulation of cell death, negative regulation of endocytosis, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of angiogenesis, positive regulation of endothelial cell migration, positive regulation of histone deacetylase activity, positive regulation of neuron projection development, positive regulation of osteoblast differentiation, protein autophosphorylation, regulation of integrin-mediated signaling pathway, regulation of keratinocyte proliferation, signal transduction, small molecule metabolic process, sphingolipid biosynthetic process, sphingolipid metabolic process Golgi apparatus, cell cortex, cell-cell junction, cytoplasm, cytosol, integral to plasma membrane, nucleus, plasma membrane, trans-Golgi network ATP binding, identical protein binding, metal ion binding, phospholipid binding, protein binding, protein kinase C activity, protein serine/threonine kinase activity Human PRKD2 BHF-UCL UniProtKB {GO:0005515=PMID:19192391, GO:0008219=PMID:17077180, GO:0050852=PMID:17077180, GO:0030949=PMID:19001381, GO:0005886=GO_REF:0000039, GO:2000573=GO_REF:0000024, GO:0005634=PMID:17077180, GO:0046872=GO_REF:0000037, GO:0032757=PMID:16928771, GO:0005622=GO_REF:0000029, GO:0035556=GO_REF:0000029, GO:0005737=PMID:17077180, GO:0051091=PMID:19192391, GO:0046777=PMID:17077180, GO:0051092=PMID:16928771, GO:0005543=GO_REF:0000002, GO:0045944=PMID:17077180, GO:0070374=GO_REF:0000024, GO:0007155=GO_REF:0000037, GO:1901727=PMID:20497126, GO:0005794=GO_REF:0000039, GO:0045743=PMID:19001381, GO:0032743=GO_REF:0000024, GO:0001525=GO_REF:0000037, GO:0050862=GO_REF:0000024, GO:0005524=GO_REF:0000029, GO:0045766=PMID:19001381, GO:0045785=PMID:17951978, GO:0010595=PMID:19001381, GO:0004672=PMID:17077180, GO:0001938=PMID:19001381, GO:0061154=PMID:21488147, GO:0004674=PMID:11062248, GO:0006468=GO_REF:0000029, GO:0004697=GO_REF:0000003} Q9BZL6 Serine/threonine-protein kinase D2 protein 20110124 {GO:0005515=IPI, GO:0008219=IMP, GO:0050852=IDA, GO:0030949=IMP, GO:0005886=IEA, GO:2000573=ISS, GO:0005634=IDA, GO:0046872=IEA, GO:0032757=IMP, GO:0005622=NAS, GO:0035556=NAS, GO:0005737=IDA, GO:0051091=IMP, GO:0046777=IDA, GO:0051092=IMP, GO:0005543=IEA, GO:0045944=IDA, GO:0070374=ISS, GO:0007155=IEA, GO:1901727=IGI, GO:0005794=IEA, GO:0045743=IMP, GO:0032743=ISS, GO:0001525=IEA, GO:0050862=ISS, GO:0005524=NAS, GO:0045766=IMP, GO:0045785=IMP, GO:0010595=IMP, GO:0004672=IDA, GO:0001938=IMP, GO:0061154=TAS, GO:0004674=NAS, GO:0006468=NAS, GO:0004697=IEA} T cell receptor signaling pathway, angiogenesis, cell adhesion, cell death, endothelial tube morphogenesis, intracellular signal transduction, positive regulation of DNA biosynthetic process, positive regulation of ERK1 and ERK2 cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of T cell receptor signaling pathway, positive regulation of angiogenesis, positive regulation of cell adhesion, positive regulation of endothelial cell migration, positive regulation of endothelial cell proliferation, positive regulation of fibroblast growth factor receptor signaling pathway, positive regulation of histone deacetylase activity, positive regulation of interleukin-2 production, positive regulation of interleukin-8 production, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, positive regulation of vascular endothelial growth factor receptor signaling pathway, protein autophosphorylation, protein phosphorylation Golgi apparatus, cytoplasm, intracellular, nucleus, plasma membrane ATP binding, metal ion binding, phospholipid binding, protein binding, protein kinase C activity, protein kinase activity, protein serine/threonine kinase activity Human PRKD3 HPA UniProtKB {GO:0035556=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006468=PMID:10231560, GO:0004697=GO_REF:0000003, GO:0005524=GO_REF:0000037, GO:0007205=PMID:10231560, GO:0046872=GO_REF:0000037, GO:0042802=PMID:17196367} O94806 Serine/threonine-protein kinase D3 protein 20101115 {GO:0035556=IEA, GO:0005737=IDA, GO:0005543=IEA, GO:0016020=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006468=TAS, GO:0004697=IEA, GO:0005524=IEA, GO:0007205=TAS, GO:0046872=IEA, GO:0042802=IPI} intracellular signal transduction, protein kinase C-activating G-protein coupled receptor signaling pathway, protein phosphorylation cytoplasm, membrane, nucleolus, nucleus ATP binding, identical protein binding, metal ion binding, phospholipid binding, protein kinase C activity Human PRKDC BHF-UCL UniProtKB {GO:0005515=PMID:21575865, GO:0001756=GO_REF:0000019, GO:0004677=PMID:15194694, GO:0005634=GO_REF:0000019, GO:0006303=Reactome:REACT_1022, GO:0035234=GO_REF:0000019, GO:0006302=Reactome:REACT_2054, GO:0007507=GO_REF:0000019, GO:0031648=GO_REF:0000019, GO:0018105=PMID:19303849, GO:0000723=GO_REF:0000019, GO:0045944=PMID:19303849, GO:0016773=GO_REF:0000002, GO:0002360=GO_REF:0000019, GO:0002328=GO_REF:0000019, GO:0005958=PMID:15194694, GO:0002326=GO_REF:0000019, GO:0010332=GO_REF:0000019, GO:0005667=PMID:19303849, GO:0032869=PMID:19303849, GO:0033077=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0033152=GO_REF:0000019, GO:0033153=GO_REF:0000019, GO:0005730=GO_REF:0000039, GO:0006915=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0070419=PMID:20383123, GO:0006281=Reactome:REACT_216, GO:0004672=PMID:7671312, GO:0004674=PMID:19303849, GO:0007420=GO_REF:0000019, GO:0005654=Reactome:REACT_6774, GO:0019899=GO_REF:0000019, GO:0006464=PMID:7671312, GO:0008134=PMID:19303849} P78527 DNA-dependent protein kinase catalytic subunit protein 20090915 {GO:0005515=IPI, GO:0001756=IEA, GO:0004677=IDA, GO:0005634=IEA, GO:0006303=TAS, GO:0035234=IEA, GO:0006302=TAS, GO:0007507=IEA, GO:0031648=IEA, GO:0018105=IDA, GO:0000723=IEA, GO:0045944=IMP, GO:0016773=IEA, GO:0002360=IEA, GO:0002328=IEA, GO:0005958=IDA, GO:0002326=IEA, GO:0010332=IEA, GO:0005667=IDA, GO:0032869=IMP, GO:0033077=IEA, GO:0043065=IEA, GO:0033152=IEA, GO:0033153=IEA, GO:0005730=IEA, GO:0006915=IEA, GO:0005524=IEA, GO:0003677=IEA, GO:0070419=IDA, GO:0006281=TAS, GO:0004672=TAS, GO:0004674=IDA, GO:0007420=IEA, GO:0005654=TAS, GO:0019899=IEA, GO:0006464=TAS, GO:0008134=IPI} B cell lineage commitment, DNA repair, T cell differentiation in thymus, T cell lineage commitment, T cell receptor V(D)J recombination, apoptotic process, brain development, cellular protein modification process, cellular response to insulin stimulus, double-strand break repair, double-strand break repair via nonhomologous end joining, germ cell programmed cell death, heart development, immunoglobulin V(D)J recombination, peptidyl-serine phosphorylation, positive regulation of apoptotic process, positive regulation of transcription from RNA polymerase II promoter, pro-B cell differentiation, protein destabilization, response to gamma radiation, somitogenesis, telomere maintenance DNA-dependent protein kinase-DNA ligase 4 complex, nonhomologous end joining complex, nucleolus, nucleoplasm, nucleus, transcription factor complex ATP binding, DNA binding, DNA-dependent protein kinase activity, enzyme binding, phosphotransferase activity, alcohol group as acceptor, protein binding, protein kinase activity, protein serine/threonine kinase activity, transcription factor binding Human UniProtKB:P22415 PRKG1 InterPro UniProtKB {GO:0005515=PMID:16990611, GO:0030036=PMID:10851246, GO:0005794=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0005246=PMID:21402151, GO:0090331=PMID:16990611, GO:0005524=GO_REF:0000002, GO:0043087=PMID:14608379, GO:0016358=GO_REF:0000019, GO:0005829=Reactome:REACT_24000, GO:0007165=GO_REF:0000019, GO:0005737=PMID:21402151, GO:0030553=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0006468=PMID:10851246, GO:0030900=GO_REF:0000019, GO:0004692=GO_REF:0000002, GO:0001764=GO_REF:0000019} Q5SQU3 cGMP-dependent protein kinase 1 protein 20130413 {GO:0005515=IPI, GO:0030036=TAS, GO:0005794=IEA, GO:0005886=IEA, GO:0005246=IDA, GO:0090331=IMP, GO:0005524=IEA, GO:0043087=IMP, GO:0016358=IEA, GO:0005829=TAS, GO:0007165=IEA, GO:0005737=IDA, GO:0030553=IEA, GO:0007596=TAS, GO:0006468=TAS, GO:0030900=IEA, GO:0004692=IEA, GO:0001764=IEA} actin cytoskeleton organization, blood coagulation, dendrite development, forebrain development, negative regulation of platelet aggregation, neuron migration, protein phosphorylation, regulation of GTPase activity, signal transduction Golgi apparatus, cytoplasm, cytosol, plasma membrane ATP binding, cGMP binding, cGMP-dependent protein kinase activity, calcium channel regulator activity, protein binding Human InterPro:IPR000719|InterPro:IPR000961|InterPro:IPR002290|InterPro:IPR002374|InterPro:IPR017441 PRKG2 Reactome UniProtKB {GO:0050999=Reactome:REACT_12389, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_111245, GO:0007165=PMID:8607838, GO:0016324=GO_REF:0000039, GO:0004672=PMID:8607838, GO:0030553=GO_REF:0000037, GO:0004674=GO_REF:0000038, GO:0007596=Reactome:REACT_604, GO:0006468=PMID:8607838, GO:0046209=Reactome:REACT_12508, GO:0004692=GO_REF:0000003} Q13237 cGMP-dependent protein kinase 2 protein 20130301 {GO:0050999=TAS, GO:0044281=TAS, GO:0005524=IEA, GO:0005829=TAS, GO:0007165=TAS, GO:0016324=IEA, GO:0004672=TAS, GO:0030553=IEA, GO:0004674=IEA, GO:0007596=TAS, GO:0006468=TAS, GO:0046209=TAS, GO:0004692=IEA} blood coagulation, nitric oxide metabolic process, protein phosphorylation, regulation of nitric-oxide synthase activity, signal transduction, small molecule metabolic process apical plasma membrane, cytosol ATP binding, cGMP binding, cGMP-dependent protein kinase activity, protein kinase activity, protein serine/threonine kinase activity Human PRKRA GOC UniProtKB {GO:0003725=GO_REF:0000002, GO:0005515=PMID:17452327, GO:0010467=Reactome:REACT_71, GO:0048471=GO_REF:0000039, GO:0008285=PMID:9687506, GO:0030422=PMID:17452327, GO:0006950=GO_REF:0000019, GO:0048705=GO_REF:0000019, GO:0006917=GO_REF:0000019, GO:0043085=PMID:9687506, GO:0009615=PMID:9687506, GO:0042803=PMID:17452327, GO:0005829=Reactome:REACT_118784, GO:0005622=GO_REF:0000019, GO:0006955=PMID:9687506, GO:0005737=GO_REF:0000054, GO:0016301=GO_REF:0000038, GO:0006468=GO_REF:0000019, GO:0042474=GO_REF:0000019, GO:0042473=GO_REF:0000019, GO:0008047=PMID:9687506} O75569 Interferon-inducible double stranded RNA-dependent protein kinase activator A protein 20130413 {GO:0003725=IEA, GO:0005515=IPI, GO:0010467=TAS, GO:0048471=IEA, GO:0008285=TAS, GO:0030422=IDA, GO:0006950=IEA, GO:0048705=IEA, GO:0006917=IEA, GO:0043085=TAS, GO:0009615=TAS, GO:0042803=IPI, GO:0005829=TAS, GO:0005622=IEA, GO:0006955=TAS, GO:0005737=IDA, GO:0016301=IEA, GO:0006468=IEA, GO:0042474=IEA, GO:0042473=IEA, GO:0008047=TAS} gene expression, immune response, induction of apoptosis, middle ear morphogenesis, negative regulation of cell proliferation, outer ear morphogenesis, positive regulation of catalytic activity, production of siRNA involved in RNA interference, protein phosphorylation, response to stress, response to virus, skeletal system morphogenesis cytoplasm, cytosol, intracellular, perinuclear region of cytoplasm double-stranded RNA binding, enzyme activator activity, kinase activity, protein binding, protein homodimerization activity Human PRKRIP1 UniProtKB UniProtKB {GO:0003725=GO_REF:0000019, GO:0019901=GO_REF:0000019, GO:0005730=GO_REF:0000039, GO:0004860=GO_REF:0000019} Q9H875 PRKR-interacting protein 1 protein 20130413 {GO:0003725=IEA, GO:0019901=IEA, GO:0005730=IEA, GO:0004860=IEA} nucleolus double-stranded RNA binding, protein kinase binding, protein kinase inhibitor activity Human UniProtKB-SubCell:SL-0188 PRKRIR PINC UniProtKB {GO:0007165=PMID:9447982, GO:0008285=PMID:9447982, GO:0016301=GO_REF:0000038, GO:0006950=PMID:9447982, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0046872=GO_REF:0000037} O43422 52 kDa repressor of the inhibitor of the protein kinase protein 20030904 {GO:0007165=TAS, GO:0008285=TAS, GO:0016301=IEA, GO:0006950=TAS, GO:0046983=IEA, GO:0005634=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0046872=IEA} negative regulation of cell proliferation, response to stress, signal transduction nucleus DNA binding, kinase activity, metal ion binding, nucleic acid binding, protein dimerization activity Human PRKX HPA UniProtKB {GO:0005515=PMID:22939624, GO:0030334=PMID:17980165, GO:0031589=PMID:16491121, GO:0005634=GO_REF:0000052, GO:0001525=PMID:21684272, GO:0060562=PMID:17980165, GO:2000696=PMID:17980165, GO:0005524=GO_REF:0000037, GO:0030155=PMID:17980165, GO:0042802=PMID:16491121, GO:0005737=PMID:21684272, GO:0046777=PMID:10026146, GO:0018105=PMID:16491121, GO:0043542=PMID:21684272, GO:0001935=PMID:21684272, GO:0060993=PMID:17980165, GO:0030099=PMID:9860982, GO:0007155=PMID:21684272, GO:0004691=PMID:17980165} P51817 cAMP-dependent protein kinase catalytic subunit PRKX protein 20090616 {GO:0005515=IPI, GO:0030334=IDA, GO:0031589=IMP, GO:0005634=IDA, GO:0001525=IMP, GO:0060562=IDA, GO:2000696=IDA, GO:0005524=IEA, GO:0030155=IDA, GO:0042802=IPI, GO:0005737=IDA, GO:0046777=IDA, GO:0018105=IDA, GO:0043542=IMP, GO:0001935=IMP, GO:0060993=IDA, GO:0030099=IDA, GO:0007155=IMP, GO:0004691=IDA} angiogenesis, cell adhesion, cell-substrate adhesion, endothelial cell migration, endothelial cell proliferation, epithelial tube morphogenesis, kidney morphogenesis, myeloid cell differentiation, peptidyl-serine phosphorylation, protein autophosphorylation, regulation of cell adhesion, regulation of cell migration, regulation of epithelial cell differentiation involved in kidney development cytoplasm, nucleus ATP binding, cAMP-dependent protein kinase activity, identical protein binding, protein binding Human PRL BHF-UCL UniProtKB {GO:0007565=PMID:7221563, GO:0005148=PMID:10854700, GO:0007595=GO_REF:0000037, GO:0005179=GO_REF:0000037, GO:0008283=PMID:10854700, GO:0040014=PMID:8421089, GO:0005576=Reactome:REACT_116060, GO:0060397=Reactome:REACT_111133, GO:0007166=PMID:10854700, GO:0046427=PMID:12552091} P01236 Prolactin protein 20081209 {GO:0007565=NAS, GO:0005148=TAS, GO:0007595=IEA, GO:0005179=IEA, GO:0008283=TAS, GO:0040014=IEP, GO:0005576=TAS, GO:0060397=TAS, GO:0007166=TAS, GO:0046427=IDA} JAK-STAT cascade involved in growth hormone signaling pathway, cell proliferation, cell surface receptor signaling pathway, female pregnancy, lactation, positive regulation of JAK-STAT cascade, regulation of multicellular organism growth extracellular region hormone activity, prolactin receptor binding Human PRLH Reactome UniProtKB {GO:0006629=GO_REF:0000019, GO:0032868=GO_REF:0000019, GO:0031861=GO_REF:0000019, GO:0005576=Reactome:REACT_16922, GO:0002023=GO_REF:0000019, GO:0048483=GO_REF:0000019, GO:0009749=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0006112=GO_REF:0000019, GO:0001894=GO_REF:0000019, GO:0007186=GO_REF:0000019, GO:0005179=PMID:9607765, GO:0045444=GO_REF:0000019, GO:0005184=GO_REF:0000019} P81277 Prolactin-releasing peptide protein 20081217 {GO:0006629=IEA, GO:0032868=IEA, GO:0031861=IEA, GO:0005576=TAS, GO:0002023=IEA, GO:0048483=IEA, GO:0009749=IEA, GO:0005737=IEA, GO:0006112=IEA, GO:0001894=IEA, GO:0007186=IEA, GO:0005179=TAS, GO:0045444=IEA, GO:0005184=IEA} G-protein coupled receptor signaling pathway, autonomic nervous system development, energy reserve metabolic process, fat cell differentiation, lipid metabolic process, reduction of food intake in response to dietary excess, response to glucose stimulus, response to insulin stimulus, tissue homeostasis cytoplasm, extracellular region hormone activity, neuropeptide hormone activity, prolactin-releasing peptide receptor binding Human PRLHR GOC UniProtKB {GO:0007631=GO_REF:0000019, GO:0007565=PMID:9607765, GO:0004983=GO_REF:0000002, GO:0005886=Reactome:REACT_16922, GO:0007186=PMID:8666380, GO:0007218=PMID:9607765, GO:0005887=PMID:8666380, GO:0004930=PMID:8666380, GO:0042445=GO_REF:0000019, GO:0008188=PMID:9607765} P49683 Prolactin-releasing peptide receptor protein 20130413 {GO:0007631=IEA, GO:0007565=TAS, GO:0004983=IEA, GO:0005886=TAS, GO:0007186=TAS, GO:0007218=TAS, GO:0005887=TAS, GO:0004930=TAS, GO:0042445=IEA, GO:0008188=TAS} G-protein coupled receptor signaling pathway, feeding behavior, female pregnancy, hormone metabolic process, neuropeptide signaling pathway integral to plasma membrane, plasma membrane G-protein coupled receptor activity, neuropeptide Y receptor activity, neuropeptide receptor activity Human PRLR InterPro UniProtKB {GO:0042978=PMID:10585417, GO:0006694=PMID:10585417, GO:0043066=PMID:10585417, GO:0038161=PMID:2558309, GO:0004896=GO_REF:0000002, GO:0042977=PMID:10585417, GO:0005886=Reactome:REACT_116060, GO:0009986=PMID:10585417, GO:0007566=PMID:9009200, GO:0004925=PMID:10585417, GO:0005576=GO_REF:0000039, GO:0060397=Reactome:REACT_111133, GO:0042803=PMID:10585417, GO:0046872=GO_REF:0000037, GO:0031904=Reactome:REACT_115907, GO:0007171=PMID:10585417, GO:0042110=PMID:10585417, GO:0016020=GO_REF:0000002, GO:0007595=PMID:10585417, GO:0016021=GO_REF:0000037, GO:0017046=PMID:7984244, GO:0007166=PMID:10585417} Q8TD76 Prolactin receptor protein 20130413 {GO:0042978=NAS, GO:0006694=NAS, GO:0043066=NAS, GO:0038161=TAS, GO:0004896=IEA, GO:0042977=NAS, GO:0005886=TAS, GO:0009986=IDA, GO:0007566=TAS, GO:0004925=NAS, GO:0005576=IEA, GO:0060397=TAS, GO:0042803=NAS, GO:0046872=IEA, GO:0031904=TAS, GO:0007171=IDA, GO:0042110=NAS, GO:0016020=IEA, GO:0007595=NAS, GO:0016021=IEA, GO:0017046=IPI, GO:0007166=NAS} JAK-STAT cascade involved in growth hormone signaling pathway, T cell activation, activation of JAK2 kinase activity, activation of transmembrane receptor protein tyrosine kinase activity, cell surface receptor signaling pathway, embryo implantation, lactation, negative regulation of apoptotic process, prolactin signaling pathway, steroid biosynthetic process cell surface, endosome lumen, extracellular region, integral to membrane, membrane, plasma membrane cytokine receptor activity, metal ion binding, ornithine decarboxylase activator activity, peptide hormone binding, prolactin receptor activity, protein homodimerization activity Human InterPro:IPR003528 PRM1 PINC UniProtKB {GO:0006997=GO_REF:0000019, GO:0030261=GO_REF:0000037, GO:0007286=GO_REF:0000019, GO:0006323=PMID:2081589, GO:0005654=PMID:2081589, GO:0007275=GO_REF:0000037, GO:0007283=PMID:2081589, GO:0000786=GO_REF:0000037, GO:0003677=GO_REF:0000037} P04553 Sperm protamine P1 protein 20030904 {GO:0006997=IEA, GO:0030261=IEA, GO:0007286=IEA, GO:0006323=TAS, GO:0005654=TAS, GO:0007275=IEA, GO:0007283=TAS, GO:0000786=IEA, GO:0003677=IEA} DNA packaging, chromosome condensation, multicellular organismal development, nucleus organization, spermatid development, spermatogenesis nucleoplasm, nucleosome DNA binding Human PRMT1 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0016571=PMID:19405910, GO:0008168=PMID:9545638, GO:0035241=GO_REF:0000019, GO:0018216=PMID:18657504, GO:0016275=GO_REF:0000019, GO:0005634=PMID:10749851, GO:0008170=PMID:19124016, GO:0001701=GO_REF:0000019, GO:0008469=GO_REF:0000019, GO:0031175=PMID:18773938, GO:0042054=PMID:19405910, GO:0005829=GO_REF:0000039, GO:0035242=GO_REF:0000019, GO:0045653=PMID:20442406, GO:0043234=GO_REF:0000019, GO:0044020=PMID:11448779, GO:0005737=PMID:9029147, GO:0043985=PMID:11448779, GO:0030519=GO_REF:0000019, GO:0006479=PMID:9545638, GO:0005654=GO_REF:0000039, GO:0008276=GO_REF:0000002, GO:0007166=PMID:9029147} Q99873 Protein arginine N-methyltransferase 1 protein 20130415 {GO:0005515=IPI, GO:0016571=IDA, GO:0008168=TAS, GO:0035241=IEA, GO:0018216=IDA, GO:0016275=IEA, GO:0005634=IDA, GO:0008170=IMP, GO:0001701=IEA, GO:0008469=IEA, GO:0031175=IMP, GO:0042054=IDA, GO:0005829=IEA, GO:0035242=IEA, GO:0045653=IDA, GO:0043234=IEA, GO:0044020=IDA, GO:0005737=TAS, GO:0043985=IDA, GO:0030519=IEA, GO:0006479=TAS, GO:0005654=IEA, GO:0008276=IEA, GO:0007166=TAS} cell surface receptor signaling pathway, histone H4-R3 methylation, histone methylation, in utero embryonic development, negative regulation of megakaryocyte differentiation, neuron projection development, peptidyl-arginine methylation, protein methylation cytoplasm, cytosol, nucleoplasm, nucleus, protein complex "N-methyltransferase activity, cytochrome c""-arginine N-methyltransferase activity, histone methyltransferase activity, histone methyltransferase activity (H4-R3 specific), histone-arginine N-methyltransferase activity, methyltransferase activity, protein binding, protein methyltransferase activity, protein-arginine omega-N asymmetric methyltransferase activity, protein-arginine omega-N monomethyltransferase activity, snoRNP binding""" Human UniProtKB:P04591:PRO_0000038596 PRMT10 InterPro UniProtKB {GO:0005737=GO_REF:0000002, GO:0008168=GO_REF:0000038, GO:0006479=GO_REF:0000002, GO:0008276=GO_REF:0000002} Q6P2P2 Putative protein arginine N-methyltransferase 10 protein 20130413 {GO:0005737=IEA, GO:0008168=IEA, GO:0006479=IEA, GO:0008276=IEA} protein methylation cytoplasm methyltransferase activity, protein methyltransferase activity Human InterPro:IPR010456 PRMT2 GOC UniProtKB {GO:0005515=PMID:16616919, GO:0008168=GO_REF:0000038, GO:0005634=PMID:11513728, GO:0033142=PMID:12039952, GO:0050681=PMID:17587566, GO:0042974=PMID:12039952, GO:0042975=PMID:12039952, GO:0008469=GO_REF:0000024, GO:0042803=PMID:12039952, GO:0005829=PMID:17587566, GO:0042054=PMID:19405910, GO:0046966=PMID:12039952, GO:0005737=PMID:11513728, GO:0035189=GO_REF:0000024, GO:0006479=PMID:9545638, GO:0004871=PMID:9545638, GO:0016571=PMID:19405910, GO:0030331=PMID:12039952, GO:0003713=PMID:12039952, GO:0034969=GO_REF:0000024, GO:0060765=PMID:17587566, GO:0016274=GO_REF:0000024, GO:0032088=PMID:16648481, GO:2000134=GO_REF:0000024, GO:0035246=GO_REF:0000024, GO:0006917=PMID:16648481, GO:0048588=GO_REF:0000024, GO:0007165=PMID:9545638, GO:0045893=PMID:12039952, GO:0045892=PMID:16648481} P55345 Protein arginine N-methyltransferase 2 protein 20130413 {GO:0005515=IPI, GO:0008168=IEA, GO:0005634=IDA, GO:0033142=IPI, GO:0050681=IPI, GO:0042974=IPI, GO:0042975=IPI, GO:0008469=ISS, GO:0042803=IPI, GO:0005829=IDA, GO:0042054=IDA, GO:0046966=IPI, GO:0005737=IDA, GO:0035189=ISS, GO:0006479=TAS, GO:0004871=TAS, GO:0016571=IDA, GO:0030331=IPI, GO:0003713=IDA, GO:0034969=ISS, GO:0060765=IDA, GO:0016274=ISS, GO:0032088=IDA, GO:2000134=ISS, GO:0035246=ISS, GO:0006917=IDA, GO:0048588=ISS, GO:0007165=TAS, GO:0045893=IDA, GO:0045892=IDA} developmental cell growth, histone arginine methylation, histone methylation, induction of apoptosis, negative regulation of G1/S transition of mitotic cell cycle, negative regulation of NF-kappaB transcription factor activity, negative regulation of transcription, DNA-dependent, peptidyl-arginine N-methylation, positive regulation of transcription, DNA-dependent, protein methylation, regulation of androgen receptor signaling pathway, signal transduction Rb-E2F complex, cytoplasm, cytosol, nucleus androgen receptor binding, estrogen receptor binding, histone methyltransferase activity, histone-arginine N-methyltransferase activity, methyltransferase activity, peroxisome proliferator activated receptor binding, progesterone receptor binding, protein binding, protein homodimerization activity, protein-arginine N-methyltransferase activity, retinoic acid receptor binding, signal transducer activity, thyroid hormone receptor binding, transcription coactivator activity Human UniProtKB:Q9R144 PRMT3 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0005737=PMID:9642256, GO:0016274=PMID:9642256, GO:0005840=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0035242=GO_REF:0000019, GO:0005829=GO_REF:0000019} O60678 Protein arginine N-methyltransferase 3 protein 20061026 {GO:0008150=ND, GO:0005737=NAS, GO:0016274=NAS, GO:0005840=IEA, GO:0008270=IEA, GO:0035242=IEA, GO:0005829=IEA} biological_process cytoplasm, cytosol, ribosome protein-arginine N-methyltransferase activity, protein-arginine omega-N asymmetric methyltransferase activity, zinc ion binding Human PRMT5 GOC UniProtKB {GO:0019918=PMID:17709427, GO:0005515=PMID:20951943, GO:0010467=Reactome:REACT_71, GO:0007088=PMID:9843966, GO:0016070=Reactome:REACT_21257, GO:0008283=PMID:9843966, GO:0008168=PMID:15369763, GO:0018216=PMID:17709427, GO:0005634=GO_REF:0000052, GO:0034660=Reactome:REACT_11052, GO:0035246=PMID:15369763, GO:0000122=GO_REF:0000019, GO:0000387=Reactome:REACT_11066, GO:0008469=GO_REF:0000003, GO:0006351=GO_REF:0000037, GO:0035243=PMID:17709427, GO:0005829=Reactome:REACT_10041, GO:0043234=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0043985=PMID:18404153, GO:0003682=GO_REF:0000019, GO:0006479=GO_REF:0000002, GO:0043021=PMID:17709427, GO:0042118=PMID:22269951} O14744 Protein arginine N-methyltransferase 5 protein 20130413 {GO:0019918=IMP, GO:0005515=IPI, GO:0010467=TAS, GO:0007088=TAS, GO:0016070=TAS, GO:0008283=TAS, GO:0008168=IDA, GO:0018216=IMP, GO:0005634=IDA, GO:0034660=TAS, GO:0035246=IDA, GO:0000122=IEA, GO:0000387=TAS, GO:0008469=IEA, GO:0006351=IEA, GO:0035243=IMP, GO:0005829=TAS, GO:0043234=IEA, GO:0005737=IDA, GO:0043985=NAS, GO:0003682=IEA, GO:0006479=IEA, GO:0043021=IPI, GO:0042118=IMP} RNA metabolic process, cell proliferation, endothelial cell activation, gene expression, histone H4-R3 methylation, ncRNA metabolic process, negative regulation of transcription from RNA polymerase II promoter, peptidyl-arginine N-methylation, peptidyl-arginine methylation, peptidyl-arginine methylation, to symmetrical-dimethyl arginine, protein methylation, regulation of mitosis, spliceosomal snRNP assembly, transcription, DNA-dependent cytoplasm, cytosol, nucleus, protein complex chromatin binding, histone-arginine N-methyltransferase activity, methyltransferase activity, protein binding, protein-arginine omega-N symmetric methyltransferase activity, ribonucleoprotein complex binding Human PRMT6 GOC UniProtKB {GO:0005515=PMID:16293633, GO:0070611=PMID:18079182, GO:0019919=PMID:18079182, GO:0016571=PMID:19405910, GO:0070612=PMID:18079182, GO:0035241=PMID:16600869, GO:0005634=PMID:11724789, GO:0006351=GO_REF:0000037, GO:0042054=PMID:19405910, GO:0035242=PMID:18079182, GO:0042393=PMID:18079182, GO:0044020=PMID:18079182, GO:0043985=PMID:18079182, GO:0019048=GO_REF:0000037, GO:0006284=PMID:16600869, GO:0045892=PMID:18079182, GO:0034970=PMID:18079182} Q96LA8 Protein arginine N-methyltransferase 6 protein 20130413 {GO:0005515=IPI, GO:0070611=IDA, GO:0019919=IDA, GO:0016571=IDA, GO:0070612=IDA, GO:0035241=IDA, GO:0005634=IDA, GO:0006351=IEA, GO:0042054=IDA, GO:0035242=IDA, GO:0042393=IDA, GO:0044020=IDA, GO:0043985=IDA, GO:0019048=IEA, GO:0006284=TAS, GO:0045892=IDA, GO:0034970=IDA} base-excision repair, histone H3-R2 methylation, histone H4-R3 methylation, histone methylation, negative regulation of transcription, DNA-dependent, peptidyl-arginine methylation, to asymmetrical-dimethyl arginine, transcription, DNA-dependent, virus-host interaction nucleus histone binding, histone methyltransferase activity, histone methyltransferase activity (H2A-R3 specific), histone methyltransferase activity (H3-R2 specific), histone methyltransferase activity (H4-R3 specific), protein binding, protein-arginine omega-N asymmetric methyltransferase activity, protein-arginine omega-N monomethyltransferase activity Human PRMT7 GOC UniProtKB {GO:0019918=PMID:19110445, GO:0008168=GO_REF:0000038, GO:0005634=PMID:15494416, GO:0008469=PMID:15494416, GO:0030154=GO_REF:0000037, GO:0005829=PMID:15494416, GO:0042393=PMID:15494416, GO:0005737=GO_REF:0000002, GO:0006479=GO_REF:0000002, GO:0043046=GO_REF:0000024, GO:0006355=GO_REF:0000037, GO:0016571=PMID:15494416, GO:0034969=GO_REF:0000024, GO:0035241=PMID:15044439, GO:0043393=PMID:15044439, GO:0018216=PMID:15044439, GO:0035247=PMID:19110445, GO:0008757=PMID:15044439, GO:0016277=PMID:15494416, GO:0000387=PMID:17709427, GO:0006351=GO_REF:0000037, GO:0035243=PMID:15494416, GO:0044020=GO_REF:0000024, GO:0006349=GO_REF:0000024, GO:0043021=PMID:17709427, GO:0008276=GO_REF:0000002} Q9NVM4 Protein arginine N-methyltransferase 7 protein 20130413 {GO:0019918=IDA, GO:0008168=IEA, GO:0005634=IDA, GO:0008469=IDA, GO:0030154=IEA, GO:0005829=IDA, GO:0042393=IC, GO:0005737=IEA, GO:0006479=IEA, GO:0043046=ISS, GO:0006355=IEA, GO:0016571=IDA, GO:0034969=ISS, GO:0035241=IDA, GO:0043393=IC, GO:0018216=IDA, GO:0035247=IDA, GO:0008757=IDA, GO:0016277=IDA, GO:0000387=IMP, GO:0006351=IEA, GO:0035243=IDA, GO:0044020=ISS, GO:0006349=ISS, GO:0043021=IPI, GO:0008276=IEA} DNA methylation involved in gamete generation, cell differentiation, histone arginine methylation, histone methylation, peptidyl-arginine methylation, peptidyl-arginine methylation, to symmetrical-dimethyl arginine, peptidyl-arginine omega-N-methylation, protein methylation, regulation of gene expression by genetic imprinting, regulation of protein binding, regulation of transcription, DNA-dependent, spliceosomal snRNP assembly, transcription, DNA-dependent cytoplasm, cytosol, nucleus "S-adenosylmethionine-dependent methyltransferase activity, myelin basic protein""-arginine N-methyltransferase activity, histone binding, histone methyltransferase activity (H4-R3 specific), histone-arginine N-methyltransferase activity, methyltransferase activity, protein methyltransferase activity, protein-arginine omega-N monomethyltransferase activity, protein-arginine omega-N symmetric methyltransferase activity, ribonucleoprotein complex binding""" Human PRMT8 GOC UniProtKB {GO:0005515=PMID:16051612, GO:0019919=PMID:16051612, GO:0005886=PMID:16051612, GO:0046982=PMID:16051612, GO:0016571=PMID:16051612, GO:0034969=PMID:16051612, GO:0035241=PMID:16051612, GO:0043393=PMID:16051612, GO:0018216=PMID:16051612, GO:0005634=PMID:16051612, GO:0008757=PMID:16051612, GO:0008469=PMID:16051612, GO:0042803=PMID:16051612, GO:0042802=PMID:19060904, GO:0035242=PMID:18320585, GO:0005737=GO_REF:0000002} Q9NR22 Protein arginine N-methyltransferase 8 protein 20130413 {GO:0005515=IPI, GO:0019919=IDA, GO:0005886=IDA, GO:0046982=IDA, GO:0016571=IDA, GO:0034969=IDA, GO:0035241=IDA, GO:0043393=TAS, GO:0018216=IDA, GO:0005634=IDA, GO:0008757=IDA, GO:0008469=IDA, GO:0042803=IDA, GO:0042802=IPI, GO:0035242=IDA, GO:0005737=IEA} histone arginine methylation, histone methylation, peptidyl-arginine methylation, peptidyl-arginine methylation, to asymmetrical-dimethyl arginine, regulation of protein binding cytoplasm, nucleus, plasma membrane S-adenosylmethionine-dependent methyltransferase activity, histone-arginine N-methyltransferase activity, identical protein binding, protein binding, protein heterodimerization activity, protein homodimerization activity, protein-arginine omega-N asymmetric methyltransferase activity, protein-arginine omega-N monomethyltransferase activity Human PRND UniProtKB UniProtKB {GO:0006878=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0005507=GO_REF:0000019, GO:0051260=GO_REF:0000002, GO:0031225=GO_REF:0000037} Q9UKY0 Prion-like protein doppel protein 20130413 {GO:0006878=IEA, GO:0005886=IEA, GO:0005507=IEA, GO:0051260=IEA, GO:0031225=IEA} cellular copper ion homeostasis, protein homooligomerization anchored to membrane, plasma membrane copper ion binding Human UniProtKB-SubCell:SL-0039 PRNP BHF-UCL UniProtKB {GO:0008017=PMID:16004966, GO:0043008=GO_REF:0000019, GO:0005886=GO_REF:0000024, GO:0005783=GO_REF:0000024, GO:0046007=GO_REF:0000024, GO:0051087=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0031225=GO_REF:0000037, GO:0043433=GO_REF:0000024, GO:0042802=PMID:16286452, GO:0043231=GO_REF:0000052, GO:0005737=PMID:16004966, GO:0006878=PMID:16004966, GO:0015631=PMID:16004966, GO:0007411=Reactome:REACT_18266, GO:0007611=GO_REF:0000019, GO:0051260=GO_REF:0000002, GO:0007050=GO_REF:0000037, GO:0032689=GO_REF:0000024, GO:0006979=GO_REF:0000024, GO:0032703=GO_REF:0000024, GO:0043066=GO_REF:0000019, GO:0005794=GO_REF:0000024, GO:0005507=PMID:16294306, GO:0005730=GO_REF:0000052, GO:0070885=GO_REF:0000024, GO:0050860=GO_REF:0000024, GO:0032700=GO_REF:0000024, GO:0008152=PMID:3755672, GO:0001933=GO_REF:0000024, GO:0045121=GO_REF:0000024, GO:0046688=GO_REF:0000019, GO:0046686=GO_REF:0000019, GO:0019898=PMID:16004966} P04156 Major prion protein protein 20110223 {GO:0008017=IDA, GO:0043008=IEA, GO:0005886=ISS, GO:0005783=ISS, GO:0046007=ISS, GO:0051087=IEA, GO:0005634=IDA, GO:0031225=IEA, GO:0043433=ISS, GO:0042802=IPI, GO:0043231=IDA, GO:0005737=TAS, GO:0006878=NAS, GO:0015631=IDA, GO:0007411=TAS, GO:0007611=IEA, GO:0051260=IEA, GO:0007050=IEA, GO:0032689=ISS, GO:0006979=ISS, GO:0032703=ISS, GO:0043066=IEA, GO:0005794=ISS, GO:0005507=TAS, GO:0005730=IDA, GO:0070885=ISS, GO:0050860=ISS, GO:0032700=ISS, GO:0008152=TAS, GO:0001933=ISS, GO:0045121=ISS, GO:0046688=IEA, GO:0046686=IEA, GO:0019898=TAS} axon guidance, cell cycle arrest, cellular copper ion homeostasis, learning or memory, metabolic process, negative regulation of T cell receptor signaling pathway, negative regulation of activated T cell proliferation, negative regulation of apoptotic process, negative regulation of calcineurin-NFAT signaling cascade, negative regulation of interferon-gamma production, negative regulation of interleukin-17 production, negative regulation of interleukin-2 production, negative regulation of protein phosphorylation, negative regulation of sequence-specific DNA binding transcription factor activity, protein homooligomerization, response to cadmium ion, response to copper ion, response to oxidative stress Golgi apparatus, anchored to membrane, cytoplasm, endoplasmic reticulum, extrinsic to membrane, intracellular membrane-bounded organelle, membrane raft, nucleolus, nucleus, plasma membrane ATP-dependent protein binding, chaperone binding, copper ion binding, identical protein binding, microtubule binding, tubulin binding Human UniProtKB:P04925 PROC IntAct UniProtKB {GO:0005515=PMID:15248212, GO:0043066=PMID:12563316, GO:0004252=Reactome:REACT_1071, GO:0005886=Reactome:REACT_1071, GO:0005796=Reactome:REACT_2146, GO:0005509=GO_REF:0000002, GO:0005576=Reactome:REACT_374, GO:0050900=Reactome:REACT_12051, GO:0017187=Reactome:REACT_1132, GO:0007596=Reactome:REACT_2051, GO:0030195=PMID:15005336, GO:0006508=Reactome:REACT_733, GO:0005788=Reactome:REACT_1103, GO:0008233=GO_REF:0000019, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} P04070 Vitamin K-dependent protein C protein 20130415 {GO:0005515=IPI, GO:0043066=IMP, GO:0004252=TAS, GO:0005886=TAS, GO:0005796=TAS, GO:0005509=IEA, GO:0005576=TAS, GO:0050900=TAS, GO:0017187=TAS, GO:0007596=TAS, GO:0030195=TAS, GO:0006508=TAS, GO:0005788=TAS, GO:0008233=IEA, GO:0044267=TAS, GO:0043687=TAS} blood coagulation, cellular protein metabolic process, leukocyte migration, negative regulation of apoptotic process, negative regulation of blood coagulation, peptidyl-glutamic acid carboxylation, post-translational protein modification, proteolysis Golgi lumen, endoplasmic reticulum lumen, extracellular region, plasma membrane calcium ion binding, peptidase activity, protein binding, serine-type endopeptidase activity Human UniProtKB:P51511 PROCA1 InterPro UniProtKB {GO:0016042=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0004623=GO_REF:0000002} Q8NCQ7 Protein PROCA1 protein 20130413 {GO:0016042=IEA, GO:0005509=IEA, GO:0004623=IEA} lipid catabolic process calcium ion binding, phospholipase A2 activity Human InterPro:IPR001211 PROCR BHF-UCL UniProtKB {GO:0005515=PMID:20826780, GO:0050819=PMID:19696402, GO:0005813=GO_REF:0000019, GO:0006955=GO_REF:0000002, GO:0005887=PMID:7929370, GO:0007596=GO_REF:0000037, GO:0019882=GO_REF:0000002, GO:0042612=GO_REF:0000002, GO:0004872=PMID:7929370} Q9UNN8 Endothelial protein C receptor protein 20110803 {GO:0005515=IPI, GO:0050819=IMP, GO:0005813=IEA, GO:0006955=IEA, GO:0005887=TAS, GO:0007596=IEA, GO:0019882=IEA, GO:0042612=IEA, GO:0004872=TAS} antigen processing and presentation, blood coagulation, immune response, negative regulation of coagulation MHC class I protein complex, centrosome, integral to plasma membrane protein binding, receptor activity Human PRODH BHF-UCL UniProtKB {GO:0034641=Reactome:REACT_13, GO:0071949=PMID:15662599, GO:0019470=PMID:21998747, GO:0006537=GO_REF:0000002, GO:0006560=PMID:9385373, GO:0005759=GO_REF:0000039, GO:0008631=PMID:9305847, GO:0010133=GO_REF:0000041, GO:0005743=Reactome:REACT_1563, GO:0006562=Reactome:REACT_1002, GO:0004657=PMID:15662599, GO:0044281=Reactome:REACT_111217} O43272 Proline dehydrogenase 1, mitochondrial protein 20120710 {GO:0034641=TAS, GO:0071949=IDA, GO:0019470=TAS, GO:0006537=IEA, GO:0006560=TAS, GO:0005759=IEA, GO:0008631=NAS, GO:0010133=IEA, GO:0005743=TAS, GO:0006562=TAS, GO:0004657=IDA, GO:0044281=TAS} 4-hydroxyproline catabolic process, cellular nitrogen compound metabolic process, glutamate biosynthetic process, intrinsic apoptotic signaling pathway in response to oxidative stress, proline catabolic process, proline catabolic process to glutamate, proline metabolic process, small molecule metabolic process mitochondrial inner membrane, mitochondrial matrix FAD binding, proline dehydrogenase activity Human PROK2 Reactome UniProtKB {GO:0043066=PMID:12604792, GO:0001664=PMID:12728244, GO:0008283=PMID:12604792, GO:0005576=Reactome:REACT_22436, GO:0001525=PMID:12604792, GO:0007283=PMID:10580115, GO:0007204=PMID:12728244, GO:0019233=PMID:12728244, GO:0000187=PMID:12728244, GO:0006954=PMID:11259612, GO:0007186=PMID:11259612, GO:0006935=PMID:12604792, GO:0007218=GO_REF:0000037, GO:0045987=PMID:11259612, GO:0007623=GO_REF:0000019} Q9HC23 Prokineticin-2 protein 20091026 {GO:0043066=IDA, GO:0001664=TAS, GO:0008283=IDA, GO:0005576=TAS, GO:0001525=IDA, GO:0007283=IMP, GO:0007204=TAS, GO:0019233=TAS, GO:0000187=TAS, GO:0006954=NAS, GO:0007186=NAS, GO:0006935=IDA, GO:0007218=IEA, GO:0045987=IDA, GO:0007623=IEA} G-protein coupled receptor signaling pathway, activation of MAPK activity, angiogenesis, cell proliferation, chemotaxis, circadian rhythm, elevation of cytosolic calcium ion concentration, inflammatory response, negative regulation of apoptotic process, neuropeptide signaling pathway, positive regulation of smooth muscle contraction, sensory perception of pain, spermatogenesis extracellular region G-protein coupled receptor binding Human PROKR1 Reactome UniProtKB {GO:0043066=GO_REF:0000019, GO:0004983=GO_REF:0000002, GO:0005886=Reactome:REACT_22436, GO:0016021=GO_REF:0000037} Q8TCW9 Prokineticin receptor 1 protein 20091026 {GO:0043066=IEA, GO:0004983=IEA, GO:0005886=TAS, GO:0016021=IEA} negative regulation of apoptotic process integral to membrane, plasma membrane neuropeptide Y receptor activity Human PROKR2 Reactome UniProtKB {GO:0004983=GO_REF:0000002, GO:0005886=Reactome:REACT_22436, GO:0007623=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q8NFJ6 Prokineticin receptor 2 protein 20091026 {GO:0004983=IEA, GO:0005886=TAS, GO:0007623=IEA, GO:0016021=IEA} circadian rhythm integral to membrane, plasma membrane neuropeptide Y receptor activity Human PROL1 GOC UniProtKB {GO:0010951=PMID:17101991, GO:0004866=PMID:17101991, GO:0005576=PMID:17101991, GO:0030414=PMID:17101991, GO:0051930=PMID:17101991} Q99935 Proline-rich protein 1 protein 20130413 {GO:0010951=IDA, GO:0004866=IDA, GO:0005576=IDA, GO:0030414=IDA, GO:0051930=IDA} negative regulation of endopeptidase activity, regulation of sensory perception of pain extracellular region endopeptidase inhibitor activity, peptidase inhibitor activity Human PROM1 BHF-UCL UniProtKB {GO:0005515=PMID:18654668, GO:0072112=PMID:19092120, GO:0045296=PMID:18654668, GO:0009986=PMID:16809613, GO:0042622=PMID:18654668, GO:0060042=PMID:18654668, GO:0042805=PMID:18654668, GO:0032420=GO_REF:0000019, GO:0031528=GO_REF:0000039, GO:0010842=GO_REF:0000024, GO:0045494=PMID:18654668, GO:0005615=GO_REF:0000019, GO:0060219=PMID:18654668, GO:0005903=GO_REF:0000019, GO:2000768=PMID:16885410, GO:0072139=PMID:19092120, GO:0016324=GO_REF:0000039, GO:0005887=GO_REF:0000019, GO:0016021=GO_REF:0000002, GO:0001750=GO_REF:0000024} O43490 Prominin-1 protein 20120102 {GO:0005515=IPI, GO:0072112=IMP, GO:0045296=IPI, GO:0009986=IDA, GO:0042622=IDA, GO:0060042=IMP, GO:0042805=IDA, GO:0032420=IEA, GO:0031528=IEA, GO:0010842=ISS, GO:0045494=IMP, GO:0005615=IEA, GO:0060219=IMP, GO:0005903=IEA, GO:2000768=IMP, GO:0072139=IMP, GO:0016324=IEA, GO:0005887=IEA, GO:0016021=IEA, GO:0001750=ISS} camera-type eye photoreceptor cell differentiation, glomerular parietal epithelial cell differentiation, glomerular visceral epithelial cell differentiation, photoreceptor cell maintenance, positive regulation of nephron tubule epithelial cell differentiation, retina layer formation, retina morphogenesis in camera-type eye apical plasma membrane, brush border, cell surface, extracellular space, integral to membrane, integral to plasma membrane, microvillus membrane, photoreceptor outer segment, photoreceptor outer segment membrane, stereocilium actinin binding, cadherin binding, protein binding Human PROP1 PINC UniProtKB {GO:0005667=GO_REF:0000019, GO:0000976=GO_REF:0000002, GO:0043066=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0001568=GO_REF:0000019, GO:0008013=GO_REF:0000019, GO:0021979=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0009953=GO_REF:0000019, GO:0007417=PMID:9462743, GO:0008022=GO_REF:0000019, GO:0060126=GO_REF:0000019, GO:0048850=GO_REF:0000019, GO:0016477=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0060070=GO_REF:0000019} O75360 Homeobox protein prophet of Pit-1 protein 20030904 {GO:0005667=IEA, GO:0000976=IEA, GO:0043066=IEA, GO:0003700=IEA, GO:0001568=IEA, GO:0008013=IEA, GO:0021979=IEA, GO:0000122=IEA, GO:0009953=IEA, GO:0007417=TAS, GO:0008022=IEA, GO:0060126=IEA, GO:0048850=IEA, GO:0016477=IEA, GO:0003682=IEA, GO:0045944=IEA, GO:0060070=IEA} blood vessel development, canonical Wnt receptor signaling pathway, cell migration, central nervous system development, dorsal/ventral pattern formation, hypophysis morphogenesis, hypothalamus cell differentiation, negative regulation of apoptotic process, negative regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter, somatotropin secreting cell differentiation transcription factor complex beta-catenin binding, chromatin binding, protein C-terminus binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding Human PROS1 GOC UniProtKB {GO:0030449=Reactome:REACT_118707, GO:0004866=PMID:8146182, GO:0005796=Reactome:REACT_1860, GO:0005509=GO_REF:0000002, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_118836, GO:0050900=Reactome:REACT_12051, GO:0010951=PMID:8146182, GO:0017187=Reactome:REACT_1132, GO:0000139=Reactome:REACT_1860, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0002576=Reactome:REACT_318, GO:0005789=Reactome:REACT_1307, GO:0006508=Reactome:REACT_733, GO:0031093=Reactome:REACT_21351, GO:0044267=Reactome:REACT_17015, GO:0042730=GO_REF:0000037, GO:0043687=Reactome:REACT_22161} P07225 Vitamin K-dependent protein S protein 20130413 {GO:0030449=TAS, GO:0004866=TAS, GO:0005796=TAS, GO:0005509=IEA, GO:0030168=TAS, GO:0005576=TAS, GO:0050900=TAS, GO:0010951=TAS, GO:0017187=TAS, GO:0000139=TAS, GO:0007596=TAS, GO:0045087=TAS, GO:0002576=TAS, GO:0005789=TAS, GO:0006508=TAS, GO:0031093=TAS, GO:0044267=TAS, GO:0042730=IEA, GO:0043687=TAS} blood coagulation, cellular protein metabolic process, fibrinolysis, innate immune response, leukocyte migration, negative regulation of endopeptidase activity, peptidyl-glutamic acid carboxylation, platelet activation, platelet degranulation, post-translational protein modification, proteolysis, regulation of complement activation Golgi lumen, Golgi membrane, endoplasmic reticulum membrane, extracellular region, platelet alpha granule lumen calcium ion binding, endopeptidase inhibitor activity Human PROSC LIFEdb UniProtKB {GO:0005622=GO_REF:0000054, GO:0005739=GO_REF:0000019, GO:0008150=GO_REF:0000015, GO:0005737=PMID:10496079, GO:0030170=GO_REF:0000033} O94903 Proline synthase co-transcribed bacterial homolog protein protein 20100607 {GO:0005622=IDA, GO:0005739=IEA, GO:0008150=ND, GO:0005737=NAS, GO:0030170=IBA} biological_process cytoplasm, intracellular, mitochondrion pyridoxal phosphate binding Human PROSER1 null null {} null null null null {} null null null PROX1 BHF-UCL UniProtKB {GO:0005515=PMID:19264593, GO:0010468=PMID:12198161, GO:0003700=PMID:19210544, GO:0044212=PMID:19210544, GO:0055010=GO_REF:0000024, GO:0003705=GO_REF:0000024, GO:0060042=PMID:11789987, GO:0048845=GO_REF:0000024, GO:0001946=PMID:12412020, GO:0031667=GO_REF:0000019, GO:0070309=PMID:11850194, GO:0055005=GO_REF:0000024, GO:0045071=PMID:19264593, GO:0055009=GO_REF:0000024, GO:0021542=GO_REF:0000024, GO:0030910=PMID:11789987, GO:0016922=PMID:16488887, GO:0048839=GO_REF:0000019, GO:2000179=GO_REF:0000024, GO:0072574=GO_REF:0000019, GO:0001709=GO_REF:0000019, GO:0003714=PMID:19264593, GO:0000122=PMID:15205472, GO:0045787=GO_REF:0000024, GO:0010595=PMID:19210544, GO:0001889=PMID:11789987, GO:0007420=PMID:8812486, GO:0045750=PMID:12198161, GO:0045893=PMID:18815287, GO:0045892=PMID:16488887, GO:0030240=GO_REF:0000024, GO:0008284=PMID:12198161, GO:0008285=PMID:17062673, GO:0030324=PMID:8812486, GO:0045737=PMID:19210544, GO:0046619=PMID:11850194, GO:0005634=PMID:19210544, GO:0060421=GO_REF:0000024, GO:0070858=PMID:16488887, GO:0043433=PMID:16488887, GO:0060836=PMID:12198161, GO:0021516=PMID:11789987, GO:0021707=GO_REF:0000024, GO:0005737=PMID:11850194, GO:0002088=PMID:8812486, GO:0045944=GO_REF:0000019, GO:0043049=PMID:11789987, GO:0097150=GO_REF:0000024, GO:0060414=GO_REF:0000024, GO:0001822=PMID:8812486, GO:0060412=GO_REF:0000024, GO:0060214=GO_REF:0000024, GO:0060059=PMID:12692551, GO:0050693=PMID:15205472, GO:0003677=PMID:18815287, GO:0050692=PMID:15205472, GO:0043565=GO_REF:0000019, GO:0060849=PMID:18815287, GO:0001938=PMID:19210544, GO:0031016=PMID:11789987, GO:0060298=GO_REF:0000024, GO:0021915=PMID:11789987, GO:0070365=PMID:15232737, GO:2000979=GO_REF:0000024, GO:0002194=GO_REF:0000019} Q92786 Prospero homeobox protein 1 protein 20120111 {GO:0005515=IPI, GO:0010468=IDA, GO:0003700=IC, GO:0044212=IDA, GO:0055010=ISS, GO:0003705=ISS, GO:0060042=ISS, GO:0048845=ISS, GO:0001946=IDA, GO:0031667=IEA, GO:0070309=IEP, GO:0055005=ISS, GO:0045071=IDA, GO:0055009=ISS, GO:0021542=ISS, GO:0030910=ISS, GO:0016922=IPI, GO:0048839=IEA, GO:2000179=ISS, GO:0072574=IEA, GO:0001709=IEA, GO:0003714=IDA, GO:0000122=IDA, GO:0045787=ISS, GO:0010595=IDA, GO:0001889=IEP, GO:0007420=IEP, GO:0045750=IDA, GO:0045893=IMP, GO:0045892=IMP, GO:0030240=ISS, GO:0008284=IDA, GO:0008285=IMP, GO:0030324=IEP, GO:0045737=IDA, GO:0046619=ISS, GO:0005634=IDA, GO:0060421=ISS, GO:0070858=IMP, GO:0043433=IDA, GO:0060836=IDA, GO:0021516=ISS, GO:0021707=ISS, GO:0005737=IDA, GO:0002088=IEP, GO:0045944=IEA, GO:0043049=ISS, GO:0097150=ISS, GO:0060414=ISS, GO:0001822=IEP, GO:0060412=ISS, GO:0060214=ISS, GO:0060059=IEP, GO:0050693=IPI, GO:0003677=IMP, GO:0050692=IPI, GO:0043565=IEA, GO:0060849=IMP, GO:0001938=IDA, GO:0031016=IEP, GO:0060298=ISS, GO:0021915=ISS, GO:0070365=IEP, GO:2000979=ISS, GO:0002194=IEA} aorta smooth muscle tissue morphogenesis, atrial cardiac muscle tissue morphogenesis, brain development, cell fate determination, cerebellar granule cell differentiation, dentate gyrus development, dorsal spinal cord development, embryonic retina morphogenesis in camera-type eye, endocardium formation, hepatocyte cell migration, hepatocyte differentiation, hepatocyte proliferation, inner ear development, kidney development, lens development in camera-type eye, lens fiber cell morphogenesis, liver development, lung development, lymphangiogenesis, lymphatic endothelial cell differentiation, negative regulation of bile acid biosynthetic process, negative regulation of cell proliferation, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, negative regulation of viral genome replication, neural tube development, neuronal stem cell maintenance, olfactory placode formation, optic placode formation involved in camera-type eye formation, otic placode formation, pancreas development, positive regulation of S phase of mitotic cell cycle, positive regulation of cell cycle, positive regulation of cell proliferation, positive regulation of cyclin-dependent protein kinase activity, positive regulation of endothelial cell migration, positive regulation of endothelial cell proliferation, positive regulation of forebrain neuron differentiation, positive regulation of heart growth, positive regulation of neural precursor cell proliferation, positive regulation of sarcomere organization, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of gene expression, regulation of transcription involved in lymphatic endothelial cell fate commitment, response to nutrient levels, retina morphogenesis in camera-type eye, skeletal muscle thin filament assembly, venous blood vessel morphogenesis, ventricular cardiac muscle tissue morphogenesis, ventricular cardiac myofibril development, ventricular septum morphogenesis cytoplasm, nucleus DBD domain binding, DNA binding, LBD domain binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, ligand-dependent nuclear receptor binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity, transcription regulatory region DNA binding Human UniProtKB:P48437 PROZ Reactome UniProtKB {GO:0017187=Reactome:REACT_1132, GO:0004252=GO_REF:0000002, GO:0005796=Reactome:REACT_1864, GO:0007596=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0006508=Reactome:REACT_733, GO:0005788=Reactome:REACT_1864, GO:0005576=GO_REF:0000039, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} P22891 Vitamin K-dependent protein Z protein 20130301 {GO:0017187=TAS, GO:0004252=IEA, GO:0005796=TAS, GO:0007596=IEA, GO:0005509=IEA, GO:0006508=TAS, GO:0005788=TAS, GO:0005576=IEA, GO:0044267=TAS, GO:0043687=TAS} blood coagulation, cellular protein metabolic process, peptidyl-glutamic acid carboxylation, post-translational protein modification, proteolysis Golgi lumen, endoplasmic reticulum lumen, extracellular region calcium ion binding, serine-type endopeptidase activity Human PRPF18 PINC UniProtKB {GO:0006397=GO_REF:0000037, GO:0008380=GO_REF:0000037, GO:0016607=GO_REF:0000039, GO:0005634=PMID:9000057, GO:0005681=GO_REF:0000037} Q99633 Pre-mRNA-splicing factor 18 protein 20030904 {GO:0006397=IEA, GO:0008380=IEA, GO:0016607=IEA, GO:0005634=TAS, GO:0005681=IEA} RNA splicing, mRNA processing nuclear speck, nucleus, spliceosomal complex Human PRPF19 BHF-UCL UniProtKB {GO:0000209=PMID:11435423, GO:0000974=PMID:20176811, GO:0005811=GO_REF:0000019, GO:0048026=GO_REF:0000019, GO:0005515=PMID:20176811, GO:0000245=PMID:16332694, GO:0004842=PMID:11435423, GO:0008610=GO_REF:0000019, GO:0034450=PMID:11435423, GO:0001833=GO_REF:0000019, GO:0005819=GO_REF:0000039, GO:0000151=GO_REF:0000002, GO:0005634=PMID:11435423, GO:0071013=PMID:11991638, GO:0003677=GO_REF:0000037, GO:0042802=PMID:16332694, GO:0005737=PMID:11435423, GO:0048711=GO_REF:0000019, GO:0006281=GO_REF:0000037, GO:0016607=PMID:16332694, GO:0045665=GO_REF:0000019, GO:0000398=PMID:20176811} Q9UMS4 Pre-mRNA-processing factor 19 protein 20100107 {GO:0000209=IDA, GO:0000974=IDA, GO:0005811=IEA, GO:0048026=IEA, GO:0005515=IPI, GO:0000245=IMP, GO:0004842=IDA, GO:0008610=IEA, GO:0034450=IDA, GO:0001833=IEA, GO:0005819=IEA, GO:0000151=IEA, GO:0005634=IDA, GO:0071013=IDA, GO:0003677=IEA, GO:0042802=IPI, GO:0005737=IDA, GO:0048711=IEA, GO:0006281=IEA, GO:0016607=IDA, GO:0045665=IEA, GO:0000398=IDA} DNA repair, inner cell mass cell proliferation, lipid biosynthetic process, mRNA splicing, via spliceosome, negative regulation of neuron differentiation, positive regulation of astrocyte differentiation, positive regulation of mRNA splicing, via spliceosome, protein polyubiquitination, spliceosomal complex assembly Prp19 complex, catalytic step 2 spliceosome, cytoplasm, lipid particle, nuclear speck, nucleus, spindle, ubiquitin ligase complex DNA binding, identical protein binding, protein binding, ubiquitin-protein ligase activity, ubiquitin-ubiquitin ligase activity Human UniProtKB:Q9UMS4 PRPF3 HPA UniProtKB {GO:0008380=PMID:9328476, GO:0006397=PMID:9328476, GO:0005515=PMID:16189514, GO:0015030=PMID:15257298, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000038, GO:0005737=GO_REF:0000052, GO:0016607=GO_REF:0000039, GO:0000398=PMID:9328476, GO:0000375=PMID:9328476, GO:0005681=PMID:9328476, GO:0046540=GO_REF:0000002} O43395 U4/U6 small nuclear ribonucleoprotein Prp3 protein 20100326 {GO:0008380=TAS, GO:0006397=TAS, GO:0005515=IPI, GO:0015030=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0005737=IDA, GO:0016607=IEA, GO:0000398=NAS, GO:0000375=TAS, GO:0005681=NAS, GO:0046540=IEA} RNA splicing, RNA splicing, via transesterification reactions, mRNA processing, mRNA splicing, via spliceosome Cajal body, U4/U6 x U5 tri-snRNP complex, cytoplasm, nuclear speck, nucleolus, nucleus, spliceosomal complex nucleic acid binding, protein binding Human PRPF31 BHF-UCL UniProtKB {GO:0000244=PMID:15257298, GO:0005515=PMID:21385873, GO:0015030=PMID:11867543, GO:0003723=GO_REF:0000037, GO:0005690=PMID:17412961, GO:0005634=GO_REF:0000054, GO:0016607=PMID:11867543, GO:0000398=PMID:15257298, GO:0071339=PMID:15960975, GO:0043021=PMID:11867543, GO:0005684=PMID:17412961, GO:0046540=PMID:11867543, GO:0005687=PMID:17412961, GO:0070990=PMID:17412961} Q8WWY3 U4/U6 small nuclear ribonucleoprotein Prp31 protein 20091029 {GO:0000244=IMP, GO:0005515=IPI, GO:0015030=IDA, GO:0003723=IEA, GO:0005690=TAS, GO:0005634=IDA, GO:0016607=IDA, GO:0000398=IC, GO:0071339=IDA, GO:0043021=IDA, GO:0005684=IC, GO:0046540=IDA, GO:0005687=IDA, GO:0070990=IPI} assembly of spliceosomal tri-snRNP, mRNA splicing, via spliceosome Cajal body, MLL1 complex, U2-type spliceosomal complex, U4 snRNP, U4/U6 x U5 tri-snRNP complex, U4atac snRNP, nuclear speck, nucleus RNA binding, protein binding, ribonucleoprotein complex binding, snRNP binding Human GO:0000244 PRPF38A UniProtKB UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0005681=GO_REF:0000037} Q8NAV1 Pre-mRNA-splicing factor 38A protein 20130413 {GO:0008380=IEA, GO:0006397=IEA, GO:0005681=IEA} RNA splicing, mRNA processing spliceosomal complex Human UniProtKB-KW:KW-0508 PRPF38B UniProtKB UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0005681=GO_REF:0000037} Q5VTL8 Pre-mRNA-splicing factor 38B protein 20130413 {GO:0008380=IEA, GO:0006397=IEA, GO:0005681=IEA} RNA splicing, mRNA processing spliceosomal complex Human UniProtKB-KW:KW-0508 PRPF39 HPA UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q86UA1 Pre-mRNA-processing factor 39 protein 20080205 {GO:0008380=IEA, GO:0006397=IEA, GO:0005730=IDA, GO:0005634=IDA} RNA splicing, mRNA processing nucleolus, nucleus NOT Human PRPF4 HPA UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:9570313, GO:0006396=PMID:9328476, GO:0010467=Reactome:REACT_71, GO:0015030=PMID:15257298, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0071001=PMID:9570313, GO:0016607=GO_REF:0000039, GO:0000398=PMID:9570313, GO:0000375=PMID:9328476, GO:0005681=PMID:9570313, GO:0005654=Reactome:REACT_1935} O43172 U4/U6 small nuclear ribonucleoprotein Prp4 protein 20100326 {GO:0008380=TAS, GO:0005515=IPI, GO:0006396=TAS, GO:0010467=TAS, GO:0015030=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0071001=IDA, GO:0016607=IEA, GO:0000398=IC, GO:0000375=NAS, GO:0005681=IC, GO:0005654=TAS} RNA processing, RNA splicing, RNA splicing, via transesterification reactions, gene expression, mRNA splicing, via spliceosome Cajal body, U4/U6 snRNP, nuclear speck, nucleolus, nucleoplasm, nucleus, spliceosomal complex protein binding NOT Human PRPF40A HPA UniProtKB {GO:0005515=PMID:15383276, GO:0006397=GO_REF:0000037, GO:0008380=GO_REF:0000037, GO:0032465=PMID:21834987, GO:0008360=PMID:21834987, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0016363=PMID:16391387, GO:0007049=GO_REF:0000037, GO:0016607=GO_REF:0000039, GO:0016477=PMID:21834987, GO:0007010=PMID:21834987, GO:0070064=GO_REF:0000019, GO:0051301=GO_REF:0000037} O75400 Pre-mRNA-processing factor 40 homolog A protein 20110516 {GO:0005515=IPI, GO:0006397=IEA, GO:0008380=IEA, GO:0032465=IMP, GO:0008360=IMP, GO:0005730=IDA, GO:0005634=IDA, GO:0016363=IDA, GO:0007049=IEA, GO:0016607=IEA, GO:0016477=IMP, GO:0007010=IMP, GO:0070064=IEA, GO:0051301=IEA} RNA splicing, cell cycle, cell division, cell migration, cytoskeleton organization, mRNA processing, regulation of cell shape, regulation of cytokinesis nuclear matrix, nuclear speck, nucleolus, nucleus proline-rich region binding, protein binding NOT Human PRPF40B UniProtKB UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0016607=GO_REF:0000039} Q6NWY9 Pre-mRNA-processing factor 40 homolog B protein 20130413 {GO:0008380=IEA, GO:0006397=IEA, GO:0016607=IEA} RNA splicing, mRNA processing nuclear speck Human UniProtKB-SubCell:SL-0186 PRPF4B HPA UniProtKB {GO:0005515=PMID:17620599, GO:0008380=PMID:9102632, GO:0004672=PMID:9102632, GO:0000398=PMID:11991638, GO:0005694=GO_REF:0000019, GO:0004674=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0006468=PMID:9102632, GO:0005634=GO_REF:0000052, GO:0071013=PMID:11991638, GO:0005524=GO_REF:0000037} Q13523 Serine/threonine-protein kinase PRP4 homolog protein 20100326 {GO:0005515=IPI, GO:0008380=TAS, GO:0004672=TAS, GO:0000398=IC, GO:0005694=IEA, GO:0004674=IEA, GO:0005730=IDA, GO:0006468=TAS, GO:0005634=IDA, GO:0071013=IDA, GO:0005524=IEA} RNA splicing, mRNA splicing, via spliceosome, protein phosphorylation catalytic step 2 spliceosome, chromosome, nucleolus, nucleus ATP binding, protein binding, protein kinase activity, protein serine/threonine kinase activity NOT Human PRPF6 BHF-UCL UniProtKB {GO:0000244=PMID:15257298, GO:0005515=PMID:15840814, GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0000245=PMID:10788320, GO:0003723=PMID:20797886, GO:0003713=PMID:16414017, GO:0005634=PMID:16414017, GO:0050681=PMID:16414017, GO:0071013=PMID:11991638, GO:0071001=PMID:10788320, GO:0006403=PMID:20797886, GO:0016607=GO_REF:0000039, GO:0000398=PMID:15257298, GO:0000375=PMID:10788320, GO:0045944=PMID:16414017, GO:0043021=PMID:10788320, GO:0005654=Reactome:REACT_2241, GO:0005681=PMID:10788320, GO:0005682=PMID:10788320, GO:0046540=PMID:10788320} O94906 Pre-mRNA-processing factor 6 protein 20091029 {GO:0000244=IMP, GO:0005515=IPI, GO:0008380=TAS, GO:0010467=TAS, GO:0000245=NAS, GO:0003723=IDA, GO:0003713=IGI, GO:0005634=IDA, GO:0050681=IPI, GO:0071013=IDA, GO:0071001=IDA, GO:0006403=IMP, GO:0016607=IEA, GO:0000398=IC, GO:0000375=NAS, GO:0045944=IDA, GO:0043021=IDA, GO:0005654=TAS, GO:0005681=NAS, GO:0005682=IDA, GO:0046540=IDA} RNA localization, RNA splicing, RNA splicing, via transesterification reactions, assembly of spliceosomal tri-snRNP, gene expression, mRNA splicing, via spliceosome, positive regulation of transcription from RNA polymerase II promoter, spliceosomal complex assembly U4/U6 snRNP, U4/U6 x U5 tri-snRNP complex, U5 snRNP, catalytic step 2 spliceosome, nuclear speck, nucleoplasm, nucleus, spliceosomal complex RNA binding, androgen receptor binding, protein binding, ribonucleoprotein complex binding, transcription coactivator activity Human GO:0000244 PRPF8 Reactome UniProtKB {GO:0006397=PMID:9774689, GO:0005515=PMID:18951082, GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0016607=GO_REF:0000039, GO:0000398=Reactome:REACT_1753, GO:0000375=PMID:9774689, GO:0003723=GO_REF:0000037, GO:0005654=Reactome:REACT_2241, GO:0005681=GO_REF:0000002, GO:0005682=PMID:9774689, GO:0071013=PMID:11991638} Q6P2Q9 Pre-mRNA-processing-splicing factor 8 protein 20130213 {GO:0006397=TAS, GO:0005515=IPI, GO:0008380=TAS, GO:0010467=TAS, GO:0016607=IEA, GO:0000398=TAS, GO:0000375=TAS, GO:0003723=IEA, GO:0005654=TAS, GO:0005681=IEA, GO:0005682=TAS, GO:0071013=IDA} RNA splicing, RNA splicing, via transesterification reactions, gene expression, mRNA processing, mRNA splicing, via spliceosome U5 snRNP, catalytic step 2 spliceosome, nuclear speck, nucleoplasm, spliceosomal complex RNA binding, protein binding Human PRPH PINC UniProtKB {GO:0005882=PMID:1378416, GO:0042622=GO_REF:0000019, GO:0005198=GO_REF:0000002, GO:0045104=GO_REF:0000019, GO:0044299=GO_REF:0000019, GO:0005883=GO_REF:0000019} P41219 Peripherin protein 20030904 {GO:0005882=TAS, GO:0042622=IEA, GO:0005198=IEA, GO:0045104=IEA, GO:0044299=IEA, GO:0005883=IEA} intermediate filament cytoskeleton organization C-fiber, intermediate filament, neurofilament, photoreceptor outer segment membrane structural molecule activity Human PRPH2 ENSEMBL UniProtKB {GO:0060041=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037, GO:0007601=GO_REF:0000002} P23942 Peripherin-2 protein 20130413 {GO:0060041=IEA, GO:0016021=IEA, GO:0007155=IEA, GO:0007601=IEA} cell adhesion, retina development in camera-type eye, visual perception integral to membrane Human Ensembl:ENSMUSP00000024773 PRPS1 Reactome UniProtKB {GO:0000287=GO_REF:0000002, GO:0005975=Reactome:REACT_474, GO:0006221=PMID:17701896, GO:0044281=Reactome:REACT_111217, GO:0005524=PMID:16939420, GO:0009165=GO_REF:0000038, GO:0009156=GO_REF:0000002, GO:0042803=PMID:16939420, GO:0005829=Reactome:REACT_2023, GO:0007399=PMID:17701900, GO:0034418=PMID:12847698, GO:0016301=GO_REF:0000037, GO:0006144=PMID:8253776, GO:0046101=PMID:17701896, GO:0004749=Reactome:REACT_1781, GO:0009116=GO_REF:0000002, GO:0006015=Reactome:REACT_850, GO:0006164=PMID:12847698} P60891 Ribose-phosphate pyrophosphokinase 1 protein 20130213 {GO:0000287=IEA, GO:0005975=TAS, GO:0006221=NAS, GO:0044281=TAS, GO:0005524=IDA, GO:0009165=IEA, GO:0009156=IEA, GO:0042803=IPI, GO:0005829=TAS, GO:0007399=IMP, GO:0034418=IMP, GO:0016301=IEA, GO:0006144=IMP, GO:0046101=IMP, GO:0004749=EXP, GO:0009116=IEA, GO:0006015=TAS, GO:0006164=IMP} 5-phosphoribose 1-diphosphate biosynthetic process, carbohydrate metabolic process, hypoxanthine biosynthetic process, nervous system development, nucleoside metabolic process, nucleotide biosynthetic process, purine nucleobase metabolic process, purine nucleotide biosynthetic process, pyrimidine nucleotide biosynthetic process, ribonucleoside monophosphate biosynthetic process, small molecule metabolic process, urate biosynthetic process cytosol ATP binding, kinase activity, magnesium ion binding, protein homodimerization activity, ribose phosphate diphosphokinase activity Human PRPS1L1 UniProtKB UniProtKB {GO:0000287=GO_REF:0000002, GO:0016301=GO_REF:0000037, GO:0004749=GO_REF:0000024, GO:0006015=GO_REF:0000041, GO:0009116=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0005524=GO_REF:0000024, GO:0042803=GO_REF:0000024, GO:0009156=GO_REF:0000029, GO:0009165=GO_REF:0000037} P21108 Ribose-phosphate pyrophosphokinase 3 protein 20091120 {GO:0000287=IEA, GO:0016301=IEA, GO:0004749=ISS, GO:0006015=IEA, GO:0009116=IEA, GO:0005575=ND, GO:0005524=ISS, GO:0042803=ISS, GO:0009156=NAS, GO:0009165=IEA} 5-phosphoribose 1-diphosphate biosynthetic process, nucleoside metabolic process, nucleotide biosynthetic process, ribonucleoside monophosphate biosynthetic process cellular_component ATP binding, kinase activity, magnesium ion binding, protein homodimerization activity, ribose phosphate diphosphokinase activity Human UniProtKB:P60891 PRPS2 PINC UniProtKB {GO:0000287=GO_REF:0000019, GO:0016208=GO_REF:0000019, GO:0031100=GO_REF:0000019, GO:0005524=GO_REF:0000024, GO:0042803=GO_REF:0000024, GO:0009165=GO_REF:0000002, GO:0009156=GO_REF:0000002, GO:0006139=PMID:2538352, GO:0006167=GO_REF:0000019, GO:0043531=GO_REF:0000019, GO:0016301=GO_REF:0000037, GO:0004749=GO_REF:0000024, GO:0030246=GO_REF:0000019, GO:0006015=GO_REF:0000041, GO:0002189=GO_REF:0000019, GO:0019003=GO_REF:0000019} P11908 Ribose-phosphate pyrophosphokinase 2 protein 20030904 {GO:0000287=IEA, GO:0016208=IEA, GO:0031100=IEA, GO:0005524=ISS, GO:0042803=ISS, GO:0009165=IEA, GO:0009156=IEA, GO:0006139=TAS, GO:0006167=IEA, GO:0043531=IEA, GO:0016301=IEA, GO:0004749=ISS, GO:0030246=IEA, GO:0006015=IEA, GO:0002189=IEA, GO:0019003=IEA} 5-phosphoribose 1-diphosphate biosynthetic process, AMP biosynthetic process, nucleobase-containing compound metabolic process, nucleotide biosynthetic process, organ regeneration, ribonucleoside monophosphate biosynthetic process ribose phosphate diphosphokinase complex ADP binding, AMP binding, ATP binding, GDP binding, carbohydrate binding, kinase activity, magnesium ion binding, protein homodimerization activity, ribose phosphate diphosphokinase activity Human PRPSAP1 PINC UniProtKB {GO:0004857=PMID:8132556, GO:0033673=GO_REF:0000019, GO:0006139=PMID:8611620, GO:0000287=GO_REF:0000002, GO:0004749=GO_REF:0000002, GO:0030234=GO_REF:0000019, GO:0002189=GO_REF:0000019, GO:0019900=GO_REF:0000019, GO:0009165=GO_REF:0000037} Q14558 Phosphoribosyl pyrophosphate synthase-associated protein 1 protein 20030904 {GO:0004857=TAS, GO:0033673=IEA, GO:0006139=TAS, GO:0000287=IEA, GO:0004749=IEA, GO:0030234=IEA, GO:0002189=IEA, GO:0019900=IEA, GO:0009165=IEA} negative regulation of kinase activity, nucleobase-containing compound metabolic process, nucleotide biosynthetic process ribose phosphate diphosphokinase complex enzyme inhibitor activity, enzyme regulator activity, kinase binding, magnesium ion binding, ribose phosphate diphosphokinase activity Human PRPSAP2 GOC UniProtKB {GO:0004857=PMID:9545573, GO:0006139=PMID:9545573, GO:0000287=GO_REF:0000002, GO:0004749=GO_REF:0000002, GO:0002189=GO_REF:0000019, GO:0043086=PMID:9545573, GO:0009165=GO_REF:0000037} O60256 Phosphoribosyl pyrophosphate synthase-associated protein 2 protein 20130413 {GO:0004857=TAS, GO:0006139=TAS, GO:0000287=IEA, GO:0004749=IEA, GO:0002189=IEA, GO:0043086=TAS, GO:0009165=IEA} negative regulation of catalytic activity, nucleobase-containing compound metabolic process, nucleotide biosynthetic process ribose phosphate diphosphokinase complex enzyme inhibitor activity, magnesium ion binding, ribose phosphate diphosphokinase activity Human PRR11 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q96HE9 Proline-rich protein 11 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 PRR12 InterPro UniProtKB {GO:0003677=GO_REF:0000002} Q9ULL5 Proline-rich protein 12 protein 20130413 {GO:0003677=IEA} DNA binding Human InterPro:IPR017956 PRR13 HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0006351=GO_REF:0000037} Q9NZ81 Proline-rich protein 13 protein 20111111 {GO:0006355=IEA, GO:0005730=IDA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus Human PRR14 null null {} null null null null {} null null null PRR14L null null {} null null null null {} null null null PRR15 UniProtKB UniProtKB {GO:0007275=GO_REF:0000037} Q8IV56 Proline-rich protein 15 protein 20130413 {GO:0007275=IEA} multicellular organismal development Human UniProtKB-KW:KW-0217 PRR16 null null {} null null null null {} null null null PRR23B null null {} null null null null {} null null null PRR3 InterPro UniProtKB {GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} P79522 Proline-rich protein 3 protein 20130413 {GO:0008270=IEA, GO:0003676=IEA} nucleic acid binding, zinc ion binding Human InterPro:IPR000571 PRR4 PINC UniProtKB {GO:0007601=PMID:7544782, GO:0005615=PMID:7544782} Q16378 Proline-rich protein 4 protein 20030904 {GO:0007601=TAS, GO:0005615=TAS} visual perception extracellular space Human PRR5 UniProtKB UniProtKB {GO:0007049=GO_REF:0000037} P85299 Proline-rich protein 5 protein 20130413 {GO:0007049=IEA} cell cycle Human UniProtKB-KW:KW-0131 PRR5L ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019} Q6MZQ0 Proline-rich protein 5-like protein 20130413 {GO:0005739=IEA} mitochondrion Human Ensembl:ENSMUSP00000130152 PRR7 UniProtKB UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000037, GO:0045211=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q8TB68 Proline-rich protein 7 protein 20130413 {GO:0030054=IEA, GO:0005886=IEA, GO:0045211=IEA, GO:0016021=IEA} cell junction, integral to membrane, plasma membrane, postsynaptic membrane Human UniProtKB-SubCell:SL-0219 PRRC1 UniProtKB UniProtKB {GO:0005794=GO_REF:0000039} Q96M27 Protein PRRC1 protein 20130413 {GO:0005794=IEA} Golgi apparatus Human UniProtKB-SubCell:SL-0132 PRRC2A IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039} P48634 Protein PRRC2A protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0005634=IEA} cytoplasm, nucleus protein binding Human UniProtKB:P05412 PRRC2B IntAct UniProtKB {GO:0005515=PMID:16189514} Q5JSZ5 Protein PRRC2B protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:Q96KQ7 PRRC2C UniProtKB UniProtKB {GO:0008022=PMID:17577209} Q9Y520 Protein PRRC2C protein 20090724 {GO:0008022=IPI} protein C-terminus binding Human UniProtKB:Q9BQA5 PRRG1 PINC UniProtKB {GO:0005887=PMID:9256434, GO:0005509=GO_REF:0000002, GO:0005576=GO_REF:0000002} O14668 Transmembrane gamma-carboxyglutamic acid protein 1 protein 20030904 {GO:0005887=TAS, GO:0005509=IEA, GO:0005576=IEA} extracellular region, integral to plasma membrane calcium ion binding Human PRRG2 PINC UniProtKB {GO:0005887=PMID:9256434, GO:0005509=GO_REF:0000002, GO:0005576=GO_REF:0000002} O14669 Transmembrane gamma-carboxyglutamic acid protein 2 protein 20030904 {GO:0005887=TAS, GO:0005509=IEA, GO:0005576=IEA} extracellular region, integral to plasma membrane calcium ion binding Human PRRG4 HPA UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005794=GO_REF:0000052, GO:0005509=GO_REF:0000002, GO:0005576=GO_REF:0000002, GO:0016021=PMID:11171957} Q9BZD6 Transmembrane gamma-carboxyglutamic acid protein 4 protein 20080205 {GO:0003674=ND, GO:0008150=ND, GO:0005794=IDA, GO:0005509=IEA, GO:0005576=IEA, GO:0016021=NAS} biological_process Golgi apparatus, extracellular region, integral to membrane calcium ion binding, molecular_function Human PRRT2 UniProtKB UniProtKB {GO:0009607=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0045202=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q7Z6L0 Proline-rich transmembrane protein 2 protein 20130413 {GO:0009607=IEA, GO:0030054=IEA, GO:0005886=IEA, GO:0045202=IEA, GO:0016021=IEA} response to biotic stimulus cell junction, integral to membrane, plasma membrane, synapse Human UniProtKB-SubCell:SL-0258 PRRT4 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} C9JH25 Proline-rich transmembrane protein 4 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 PRRX1 HPA UniProtKB {GO:0003700=GO_REF:0000002, GO:0042472=GO_REF:0000019, GO:0051216=GO_REF:0000019, GO:0003713=PMID:1509260, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0002053=GO_REF:0000019, GO:0048844=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0030326=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0048701=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0045880=GO_REF:0000019, GO:0071837=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:0042474=GO_REF:0000019} P54821 Paired mesoderm homeobox protein 1 protein 20120912 {GO:0003700=IEA, GO:0042472=IEA, GO:0051216=IEA, GO:0003713=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0002053=IEA, GO:0048844=IEA, GO:0000122=IEA, GO:0030326=IEA, GO:0003677=IEA, GO:0048701=IEA, GO:0043565=IEA, GO:0045880=IEA, GO:0071837=IEA, GO:0060021=IEA, GO:0042474=IEA} artery morphogenesis, cartilage development, embryonic cranial skeleton morphogenesis, embryonic limb morphogenesis, inner ear morphogenesis, middle ear morphogenesis, negative regulation of transcription from RNA polymerase II promoter, palate development, positive regulation of mesenchymal cell proliferation, positive regulation of smoothened signaling pathway nucleolus, nucleus DNA binding, HMG box domain binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity Human PRRX2 UniProtKB UniProtKB {GO:0006355=PMID:9665387, GO:0003700=PMID:11063257, GO:0042472=GO_REF:0000019, GO:0051216=GO_REF:0000019, GO:0007275=GO_REF:0000038, GO:0005634=GO_REF:0000040, GO:0002053=GO_REF:0000019, GO:0048844=GO_REF:0000019, GO:0000228=GO_REF:0000029, GO:0030326=GO_REF:0000019, GO:0048701=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0045880=GO_REF:0000019, GO:0042474=GO_REF:0000019} Q99811 Paired mesoderm homeobox protein 2 protein 20021104 {GO:0006355=NAS, GO:0003700=NAS, GO:0042472=IEA, GO:0051216=IEA, GO:0007275=IEA, GO:0005634=IEA, GO:0002053=IEA, GO:0048844=IEA, GO:0000228=NAS, GO:0030326=IEA, GO:0048701=IEA, GO:0043565=IEA, GO:0045880=IEA, GO:0042474=IEA} artery morphogenesis, cartilage development, embryonic cranial skeleton morphogenesis, embryonic limb morphogenesis, inner ear morphogenesis, middle ear morphogenesis, multicellular organismal development, positive regulation of mesenchymal cell proliferation, positive regulation of smoothened signaling pathway, regulation of transcription, DNA-dependent nuclear chromosome, nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human PRSS1 Reactome UniProtKB {GO:0022617=Reactome:REACT_118572, GO:0004252=PMID:8841182, GO:0030198=Reactome:REACT_118779, GO:0007586=GO_REF:0000037, GO:0006508=GO_REF:0000037, GO:0005576=Reactome:REACT_118776, GO:0005615=GO_REF:0000039, GO:0046872=GO_REF:0000037} P07477 Trypsin-1 protein 20130301 {GO:0022617=TAS, GO:0004252=TAS, GO:0030198=TAS, GO:0007586=IEA, GO:0006508=IEA, GO:0005576=TAS, GO:0005615=IEA, GO:0046872=IEA} digestion, extracellular matrix disassembly, extracellular matrix organization, proteolysis extracellular region, extracellular space metal ion binding, serine-type endopeptidase activity Human PRSS2 Reactome UniProtKB {GO:0005515=PMID:16192646, GO:0004252=PMID:12709065, GO:0030307=PMID:12731883, GO:0007586=GO_REF:0000037, GO:0005509=PMID:12709065, GO:0005576=Reactome:REACT_150397, GO:0005615=PMID:16192646, GO:0045785=PMID:12731883, GO:0031012=PMID:12731883, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0045087=Reactome:REACT_6802, GO:0030574=Reactome:REACT_150401, GO:0006508=PMID:12731883} P07478 Trypsin-2 protein 20130301 {GO:0005515=IPI, GO:0004252=IDA, GO:0030307=TAS, GO:0007586=IEA, GO:0005509=IDA, GO:0005576=TAS, GO:0005615=IMP, GO:0045785=TAS, GO:0031012=TAS, GO:0022617=TAS, GO:0030198=TAS, GO:0045087=TAS, GO:0030574=TAS, GO:0006508=IDA} collagen catabolic process, digestion, extracellular matrix disassembly, extracellular matrix organization, innate immune response, positive regulation of cell adhesion, positive regulation of cell growth, proteolysis extracellular matrix, extracellular region, extracellular space calcium ion binding, protein binding, serine-type endopeptidase activity Human PRSS21 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0016020=PMID:9826525, GO:0005886=GO_REF:0000039, GO:0004252=GO_REF:0000019, GO:0006508=GO_REF:0000037, GO:0008236=PMID:10397266, GO:0031225=GO_REF:0000037} Q9Y6M0 Testisin protein 20080205 {GO:0005737=IDA, GO:0016020=TAS, GO:0005886=IEA, GO:0004252=IEA, GO:0006508=IEA, GO:0008236=TAS, GO:0031225=IEA} proteolysis anchored to membrane, cytoplasm, membrane, plasma membrane serine-type endopeptidase activity, serine-type peptidase activity Human PRSS23 LIFEdb UniProtKB {GO:0004252=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0005634=GO_REF:0000054, GO:0005576=GO_REF:0000039} O95084 Serine protease 23 protein 20100607 {GO:0004252=IEA, GO:0006508=IEA, GO:0005634=IDA, GO:0005576=IEA} proteolysis extracellular region, nucleus serine-type endopeptidase activity Human PRSS3 Reactome UniProtKB {GO:0005515=PMID:14507909, GO:0004252=PMID:14507909, GO:0043542=PMID:15313892, GO:0045087=Reactome:REACT_6802, GO:0007586=PMID:14507909, GO:0005509=PMID:6698368, GO:0006508=PMID:6698368, GO:0005576=Reactome:REACT_116162, GO:0005615=PMID:6698368, GO:0031638=PMID:6698368} P35030 Trypsin-3 protein 20130301 {GO:0005515=IPI, GO:0004252=IDA, GO:0043542=IMP, GO:0045087=TAS, GO:0007586=TAS, GO:0005509=IDA, GO:0006508=IDA, GO:0005576=TAS, GO:0005615=IDA, GO:0031638=IDA} digestion, endothelial cell migration, innate immune response, proteolysis, zymogen activation extracellular region, extracellular space calcium ion binding, protein binding, serine-type endopeptidase activity Human PRSS33 ENSEMBL UniProtKB {GO:0004252=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0005615=GO_REF:0000019} Q8NF86 Serine protease 33 protein 20130413 {GO:0004252=IEA, GO:0006508=IEA, GO:0005615=IEA} proteolysis extracellular space serine-type endopeptidase activity Human Ensembl:ENSMUSP00000059491 PRSS50 UniProtKB UniProtKB {GO:0005737=PMID:17283160, GO:0004252=GO_REF:0000002, GO:0005783=PMID:17283160, GO:0006508=PMID:17283160, GO:0004298=PMID:17283160} Q9UI38 Probable threonine protease PRSS50 protein 20100506 {GO:0005737=IDA, GO:0004252=IEA, GO:0005783=IDA, GO:0006508=IDA, GO:0004298=IMP} proteolysis cytoplasm, endoplasmic reticulum serine-type endopeptidase activity, threonine-type endopeptidase activity Human PRSS56 UniProtKB UniProtKB {GO:0004252=GO_REF:0000024, GO:0005783=GO_REF:0000024, GO:0006508=GO_REF:0000024, GO:0043010=PMID:21397065} P0CW18 Serine protease 56 protein 20130315 {GO:0004252=ISS, GO:0005783=ISS, GO:0006508=ISS, GO:0043010=IMP} camera-type eye development, proteolysis endoplasmic reticulum serine-type endopeptidase activity Human PRSS8 PINC UniProtKB {GO:0005515=PMID:19911255, GO:0004252=GO_REF:0000002, GO:0010765=GO_REF:0000019, GO:0006508=GO_REF:0000037, GO:0008236=PMID:8034638, GO:0005576=PMID:10077646, GO:0016021=GO_REF:0000037, GO:0005615=GO_REF:0000039} Q16651 Prostasin protein 20030904 {GO:0005515=IPI, GO:0004252=IEA, GO:0010765=IEA, GO:0006508=IEA, GO:0008236=TAS, GO:0005576=TAS, GO:0016021=IEA, GO:0005615=IEA} positive regulation of sodium ion transport, proteolysis extracellular region, extracellular space, integral to membrane protein binding, serine-type endopeptidase activity, serine-type peptidase activity Human PRTFDC1 UniProtKB UniProtKB {GO:0006178=PMID:21054786, GO:0006166=GO_REF:0000033, GO:0006168=GO_REF:0000033, GO:0000287=PMID:21054786, GO:0000166=GO_REF:0000037, GO:0046100=GO_REF:0000033, GO:0032264=GO_REF:0000033, GO:0004422=PMID:21054786, GO:0032263=GO_REF:0000033, GO:0046038=PMID:21054786, GO:0042803=PMID:21054786, GO:0005829=GO_REF:0000033} Q9NRG1 Phosphoribosyltransferase domain-containing protein 1 protein 20110210 {GO:0006178=IDA, GO:0006166=IBA, GO:0006168=IBA, GO:0000287=TAS, GO:0000166=IEA, GO:0046100=IBA, GO:0032264=IBA, GO:0004422=IDA, GO:0032263=IBA, GO:0046038=IDA, GO:0042803=IPI, GO:0005829=IBA} GMP catabolic process, GMP salvage, IMP salvage, adenine salvage, guanine salvage, hypoxanthine metabolic process, purine ribonucleoside salvage cytosol hypoxanthine phosphoribosyltransferase activity, magnesium ion binding, nucleotide binding, protein homodimerization activity NOT Human PRTG UniProtKB UniProtKB {GO:0007275=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q2VWP7 Protogenin protein 20130413 {GO:0007275=IEA, GO:0016021=IEA} multicellular organismal development integral to membrane Human UniProtKB-KW:KW-0812 PRTN3 IntAct UniProtKB {GO:0005515=PMID:15527767, GO:0050765=PMID:17712045, GO:0008284=PMID:2598267, GO:0004252=GO_REF:0000002, GO:0030574=GO_REF:0000037, GO:0006508=GO_REF:0000037, GO:0008236=GO_REF:0000029, GO:0019899=PMID:17712045, GO:0097029=PMID:16478888} P24158 Myeloblastin protein 20130415 {GO:0005515=IPI, GO:0050765=IDA, GO:0008284=TAS, GO:0004252=IEA, GO:0030574=IEA, GO:0006508=IEA, GO:0008236=NAS, GO:0019899=IPI, GO:0097029=IDA} collagen catabolic process, mature dendritic cell differentiation, negative regulation of phagocytosis, positive regulation of cell proliferation, proteolysis enzyme binding, protein binding, serine-type endopeptidase activity, serine-type peptidase activity Human UniProtKB:P84022 PRUNE HPA UniProtKB {GO:0005515=PMID:10602478, GO:0005737=GO_REF:0000052, GO:0016462=GO_REF:0000002, GO:0030145=GO_REF:0000002, GO:0004427=GO_REF:0000003, GO:0005634=GO_REF:0000039, GO:0005925=GO_REF:0000039} Q86TP1 Protein prune homolog protein 20111111 {GO:0005515=IPI, GO:0005737=IDA, GO:0016462=IEA, GO:0030145=IEA, GO:0004427=IEA, GO:0005634=IEA, GO:0005925=IEA} cytoplasm, focal adhesion, nucleus inorganic diphosphatase activity, manganese ion binding, protein binding, pyrophosphatase activity Human PRUNE2 HPA UniProtKB {GO:0016462=GO_REF:0000002, GO:0005794=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0046872=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q8WUY3 Protein prune homolog 2 protein 20120912 {GO:0016462=IEA, GO:0005794=IDA, GO:0006915=IEA, GO:0005634=IDA, GO:0046872=IEA, GO:0043231=IDA} apoptotic process Golgi apparatus, intracellular membrane-bounded organelle, nucleus metal ion binding, pyrophosphatase activity Human PRX IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0003674=GO_REF:0000015, GO:0008219=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0008366=PMID:11133365} Q9BXM0 Periaxin protein 20130415 {GO:0005515=IPI, GO:0003674=ND, GO:0008219=IEA, GO:0005737=IEA, GO:0005886=IEA, GO:0005634=IEA, GO:0005575=ND, GO:0008366=NAS} axon ensheathment, cell death cellular_component, cytoplasm, nucleus, plasma membrane molecular_function, protein binding Human UniProtKB:P16333 PSAP GOC UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0005794=GO_REF:0000052, GO:0060736=GO_REF:0000019, GO:0006687=Reactome:REACT_116105, GO:0060742=GO_REF:0000019, GO:0071310=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_13534, GO:0044281=Reactome:REACT_111217, GO:0043085=PMID:2717620, GO:0005765=Reactome:REACT_115656, GO:0005615=PMID:22261194, GO:0005764=GO_REF:0000002, GO:0019216=GO_REF:0000019, GO:0008289=PMID:1454804, GO:0043231=GO_REF:0000052, GO:0005739=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0043408=GO_REF:0000019, GO:0006869=PMID:1454804, GO:0002576=Reactome:REACT_318, GO:0016021=PMID:1454804, GO:0008047=PMID:2717620, GO:0043202=Reactome:REACT_13534} P07602 Proactivator polypeptide protein 20130413 {GO:0006665=TAS, GO:0005794=IDA, GO:0060736=IEA, GO:0006687=TAS, GO:0060742=IEA, GO:0071310=IEA, GO:0030168=TAS, GO:0005576=TAS, GO:0044281=TAS, GO:0043085=TAS, GO:0005765=TAS, GO:0005615=ISS, GO:0005764=IEA, GO:0019216=IEA, GO:0008289=TAS, GO:0043231=IDA, GO:0005739=IEA, GO:0007596=TAS, GO:0043408=IEA, GO:0006869=TAS, GO:0002576=TAS, GO:0016021=TAS, GO:0008047=TAS, GO:0043202=TAS} blood coagulation, cellular response to organic substance, epithelial cell differentiation involved in prostate gland development, glycosphingolipid metabolic process, lipid transport, platelet activation, platelet degranulation, positive regulation of catalytic activity, prostate gland growth, regulation of MAPK cascade, regulation of lipid metabolic process, small molecule metabolic process, sphingolipid metabolic process Golgi apparatus, extracellular region, extracellular space, integral to membrane, intracellular membrane-bounded organelle, lysosomal lumen, lysosomal membrane, lysosome, mitochondrion enzyme activator activity, lipid binding Human PSAT1 Reactome UniProtKB {GO:0034641=Reactome:REACT_13, GO:0030170=GO_REF:0000002, GO:0008652=Reactome:REACT_238, GO:0004648=Reactome:REACT_116056, GO:0006564=Reactome:REACT_115789, GO:0044281=Reactome:REACT_111217, GO:0008615=PMID:10637769, GO:0005829=Reactome:REACT_116056} Q9Y617 Phosphoserine aminotransferase protein 20101018 {GO:0034641=TAS, GO:0030170=IEA, GO:0008652=TAS, GO:0004648=TAS, GO:0006564=TAS, GO:0044281=TAS, GO:0008615=NAS, GO:0005829=TAS} L-serine biosynthetic process, cellular amino acid biosynthetic process, cellular nitrogen compound metabolic process, pyridoxine biosynthetic process, small molecule metabolic process cytosol O-phospho-L-serine:2-oxoglutarate aminotransferase activity, pyridoxal phosphate binding Human PSCA UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0031225=GO_REF:0000037} O43653 Prostate stem cell antigen protein 20130413 {GO:0005886=IEA, GO:0031225=IEA} anchored to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 PSD RefGenome UniProtKB {GO:0005802=GO_REF:0000033, GO:0005086=GO_REF:0000033, GO:0007165=PMID:9417912, GO:0030054=GO_REF:0000033, GO:0005543=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0030182=GO_REF:0000033, GO:0032012=GO_REF:0000002, GO:0004871=PMID:9417912, GO:0016021=GO_REF:0000019, GO:0016192=GO_REF:0000033, GO:0001726=GO_REF:0000039} A5PKW4 PH and SEC7 domain-containing protein 1 protein 20120409 {GO:0005802=IBA, GO:0005086=IBA, GO:0007165=NAS, GO:0030054=IBA, GO:0005543=IEA, GO:0005886=IEA, GO:0030182=IBA, GO:0032012=IEA, GO:0004871=NAS, GO:0016021=IEA, GO:0016192=IBA, GO:0001726=IEA} neuron differentiation, regulation of ARF protein signal transduction, signal transduction, vesicle-mediated transport cell junction, integral to membrane, plasma membrane, ruffle, trans-Golgi network ARF guanyl-nucleotide exchange factor activity, phospholipid binding, signal transducer activity Human PANTHER:PTN000070946 PSD2 RefGenome UniProtKB {GO:0005802=GO_REF:0000033, GO:0005086=GO_REF:0000033, GO:0030054=GO_REF:0000033, GO:0005543=GO_REF:0000002, GO:0030182=GO_REF:0000033, GO:0043025=GO_REF:0000019, GO:0032012=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0016192=GO_REF:0000033, GO:0030425=GO_REF:0000019} Q9BQI7 PH and SEC7 domain-containing protein 2 protein 20120409 {GO:0005802=IBA, GO:0005086=IBA, GO:0030054=IBA, GO:0005543=IEA, GO:0030182=IBA, GO:0043025=IEA, GO:0032012=IEA, GO:0016021=IEA, GO:0016192=IBA, GO:0030425=IEA} neuron differentiation, regulation of ARF protein signal transduction, vesicle-mediated transport cell junction, dendrite, integral to membrane, neuronal cell body, trans-Golgi network ARF guanyl-nucleotide exchange factor activity, phospholipid binding Human PANTHER:PTN000070946 PSD3 RefGenome UniProtKB {GO:0005802=GO_REF:0000033, GO:0005086=GO_REF:0000033, GO:0030054=GO_REF:0000033, GO:0005543=GO_REF:0000002, GO:0005886=GO_REF:0000037, GO:0016020=GO_REF:0000019, GO:0030182=GO_REF:0000033, GO:0045211=GO_REF:0000037, GO:0014069=GO_REF:0000039, GO:0032012=GO_REF:0000002, GO:0016192=GO_REF:0000033} Q9NYI0 PH and SEC7 domain-containing protein 3 protein 20120409 {GO:0005802=IBA, GO:0005086=IBA, GO:0030054=IBA, GO:0005543=IEA, GO:0005886=IEA, GO:0016020=IEA, GO:0030182=IBA, GO:0045211=IEA, GO:0014069=IEA, GO:0032012=IEA, GO:0016192=IBA} neuron differentiation, regulation of ARF protein signal transduction, vesicle-mediated transport cell junction, membrane, plasma membrane, postsynaptic density, postsynaptic membrane, trans-Golgi network ARF guanyl-nucleotide exchange factor activity, phospholipid binding Human PANTHER:PTN000070946 PSD4 RefGenome UniProtKB {GO:0005802=GO_REF:0000033, GO:0005086=GO_REF:0000033, GO:0030054=GO_REF:0000033, GO:0005543=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0030182=GO_REF:0000033, GO:0032012=GO_REF:0000002, GO:0016192=GO_REF:0000033} Q8NDX1 PH and SEC7 domain-containing protein 4 protein 20120409 {GO:0005802=IBA, GO:0005086=IBA, GO:0030054=IBA, GO:0005543=IEA, GO:0005886=IEA, GO:0030182=IBA, GO:0032012=IEA, GO:0016192=IBA} neuron differentiation, regulation of ARF protein signal transduction, vesicle-mediated transport cell junction, plasma membrane, trans-Golgi network ARF guanyl-nucleotide exchange factor activity, phospholipid binding Human PANTHER:PTN000070946 PSEN1 GOC UniProtKB {GO:0005515=PMID:21163940, GO:0031594=GO_REF:0000033, GO:0042640=GO_REF:0000019, GO:0048705=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0051402=GO_REF:0000019, GO:0051604=GO_REF:0000019, GO:0016337=PMID:11953314, GO:0006839=GO_REF:0000019, GO:0005791=PMID:9632714, GO:0051966=GO_REF:0000019, GO:0005813=PMID:9298903, GO:0005794=PMID:9246482, GO:0009986=GO_REF:0000033, GO:0001708=GO_REF:0000019, GO:0032469=PMID:17431506, GO:0043393=GO_REF:0000019, GO:0043085=PMID:15274632, GO:0030165=PMID:10551805, GO:0021870=GO_REF:0000019, GO:0005790=PMID:9632714, GO:0004175=PMID:8755489, GO:0005887=PMID:15274632, GO:0005789=GO_REF:0000039, GO:0043589=GO_REF:0000019, GO:0050852=GO_REF:0000019, GO:0030424=GO_REF:0000033, GO:0048471=GO_REF:0000033, GO:0005783=PMID:15274632, GO:0005634=GO_REF:0000019, GO:0030426=GO_REF:0000033, GO:0005640=PMID:9246482, GO:0000186=GO_REF:0000019, GO:0048666=GO_REF:0000019, GO:0021904=GO_REF:0000019, GO:0006816=GO_REF:0000033, GO:0000045=GO_REF:0000019, GO:0002286=GO_REF:0000019, GO:0042987=PMID:15274632, GO:0001568=GO_REF:0000019, GO:0015871=GO_REF:0000019, GO:0031410=GO_REF:0000019, GO:0006974=GO_REF:0000019, GO:0048854=GO_REF:0000019, GO:0042325=PMID:9689133, GO:0016020=PMID:8878479, GO:0016021=PMID:7596406, GO:0004190=GO_REF:0000002, GO:0001764=GO_REF:0000019, GO:0030018=GO_REF:0000033, GO:0007220=PMID:15274632, GO:0008013=PMID:11104755, GO:0001756=GO_REF:0000019, GO:0048538=GO_REF:0000019, GO:0015031=GO_REF:0000019, GO:0005765=GO_REF:0000033, GO:0001947=GO_REF:0000019, GO:0015813=GO_REF:0000019, GO:0043524=GO_REF:0000019, GO:0021795=GO_REF:0000019, GO:0007219=GO_REF:0000019, GO:0016485=PMID:15274632, GO:0048167=GO_REF:0000019, GO:0007175=GO_REF:0000019, GO:0043025=GO_REF:0000033, GO:0051444=GO_REF:0000019, GO:0007613=GO_REF:0000019, GO:0006509=PMID:15274632, GO:0006979=GO_REF:0000019, GO:0005938=GO_REF:0000033, GO:0005262=PMID:16959576, GO:0031965=PMID:9298903, GO:0045296=GO_REF:0000033, GO:0000122=GO_REF:0000019, GO:0060075=GO_REF:0000019, GO:0050673=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0002573=GO_REF:0000019, GO:0070588=PMID:16959576, GO:0000776=PMID:9298903, GO:0050771=GO_REF:0000019, GO:0006486=GO_REF:0000019, GO:0045121=GO_REF:0000033, GO:0016080=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0032436=GO_REF:0000019, GO:0005743=GO_REF:0000033, GO:0030326=GO_REF:0000019, GO:0035556=GO_REF:0000002, GO:0005739=PMID:12377771, GO:0016324=GO_REF:0000033, GO:0051563=GO_REF:0000033, GO:0043198=GO_REF:0000033, GO:0002244=GO_REF:0000019, GO:0043406=GO_REF:0000019, GO:0001921=GO_REF:0000019, GO:0043066=PMID:10805794, GO:0043065=GO_REF:0000019, GO:0070765=PMID:10801983, GO:0050820=GO_REF:0000019, GO:2000059=GO_REF:0000019, GO:0050435=GO_REF:0000033, GO:0000139=GO_REF:0000039, GO:0035253=GO_REF:0000033} P49768 Presenilin-1 protein 20130413 {GO:0005515=IPI, GO:0031594=IBA, GO:0042640=IEA, GO:0048705=IEA, GO:0009791=IEA, GO:0051402=IEA, GO:0051604=IEA, GO:0016337=IMP, GO:0006839=IEA, GO:0005791=IDA, GO:0051966=IEA, GO:0005813=IDA, GO:0005794=IDA, GO:0009986=IBA, GO:0001708=IEA, GO:0032469=IDA, GO:0043393=IEA, GO:0043085=IDA, GO:0030165=IPI, GO:0021870=IEA, GO:0005790=IDA, GO:0004175=IDA, GO:0005887=IDA, GO:0005789=IEA, GO:0043589=IEA, GO:0050852=IEA, GO:0030424=IBA, GO:0048471=IBA, GO:0005783=IDA, GO:0005634=IEA, GO:0030426=IBA, GO:0005640=IDA, GO:0000186=IEA, GO:0048666=IEA, GO:0021904=IEA, GO:0006816=IBA, GO:0000045=IEA, GO:0002286=IEA, GO:0042987=TAS, GO:0001568=IEA, GO:0015871=IEA, GO:0031410=IEA, GO:0006974=IEA, GO:0048854=IEA, GO:0042325=IDA, GO:0016020=TAS, GO:0016021=TAS, GO:0004190=IEA, GO:0001764=IEA, GO:0030018=IBA, GO:0007220=TAS, GO:0008013=IPI, GO:0001756=IEA, GO:0048538=IEA, GO:0015031=IEA, GO:0005765=IBA, GO:0001947=IEA, GO:0015813=IEA, GO:0043524=IEA, GO:0021795=IEA, GO:0007219=IEA, GO:0016485=IDA, GO:0048167=IEA, GO:0007175=IEA, GO:0043025=IBA, GO:0051444=IEA, GO:0007613=IEA, GO:0006509=IDA, GO:0006979=IEA, GO:0005938=IBA, GO:0005262=IMP, GO:0031965=IDA, GO:0045296=IBA, GO:0000122=IEA, GO:0060075=IEA, GO:0050673=IEA, GO:0043234=IEA, GO:0002573=IEA, GO:0070588=IMP, GO:0000776=IDA, GO:0050771=IEA, GO:0006486=IEA, GO:0045121=IBA, GO:0016080=IEA, GO:0005886=IEA, GO:0032436=IEA, GO:0005743=IBA, GO:0030326=IEA, GO:0035556=IEA, GO:0005739=IDA, GO:0016324=IBA, GO:0051563=IBA, GO:0043198=IBA, GO:0002244=IEA, GO:0043406=IEA, GO:0001921=IEA, GO:0043066=IDA, GO:0043065=IEA, GO:0070765=IDA, GO:0050820=IEA, GO:2000059=IEA, GO:0050435=IBA, GO:0000139=IEA, GO:0035253=IBA} Cajal-Retzius cell differentiation, L-glutamate transport, Notch receptor processing, Notch signaling pathway, T cell activation involved in immune response, T cell receptor signaling pathway, activation of MAPKK activity, amyloid precursor protein catabolic process, anagen, autophagic vacuole assembly, beta-amyloid metabolic process, blood vessel development, brain morphogenesis, calcium ion transmembrane transport, calcium ion transport, cell fate specification, cell-cell adhesion, cerebral cortex cell migration, choline transport, dorsal/ventral neural tube patterning, embryonic limb morphogenesis, endoplasmic reticulum calcium ion homeostasis, epithelial cell proliferation, heart looping, hematopoietic progenitor cell differentiation, intracellular signal transduction, membrane protein ectodomain proteolysis, memory, mitochondrial transport, myeloid leukocyte differentiation, negative regulation of apoptotic process, negative regulation of axonogenesis, negative regulation of epidermal growth factor-activated receptor activity, negative regulation of neuron apoptotic process, negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process, negative regulation of transcription from RNA polymerase II promoter, negative regulation of ubiquitin-protein ligase activity, neuron apoptotic process, neuron development, neuron migration, positive regulation of MAP kinase activity, positive regulation of apoptotic process, positive regulation of catalytic activity, positive regulation of coagulation, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of receptor recycling, post-embryonic development, protein glycosylation, protein maturation, protein processing, protein transport, regulation of phosphorylation, regulation of protein binding, regulation of resting membrane potential, regulation of synaptic plasticity, regulation of synaptic transmission, glutamatergic, response to DNA damage stimulus, response to oxidative stress, skeletal system morphogenesis, skin morphogenesis, smooth endoplasmic reticulum calcium ion homeostasis, somitogenesis, synaptic vesicle targeting, thymus development Golgi apparatus, Golgi membrane, Z disc, apical plasma membrane, axon, cell cortex, cell surface, centrosome, ciliary rootlet, cytoplasmic vesicle, dendritic shaft, endoplasmic reticulum, endoplasmic reticulum membrane, gamma-secretase complex, growth cone, integral to membrane, integral to plasma membrane, kinetochore, lysosomal membrane, membrane, membrane raft, mitochondrial inner membrane, mitochondrion, neuromuscular junction, neuronal cell body, nuclear membrane, nuclear outer membrane, nucleus, perinuclear region of cytoplasm, plasma membrane, protein complex, rough endoplasmic reticulum, smooth endoplasmic reticulum PDZ domain binding, aspartic-type endopeptidase activity, beta-catenin binding, cadherin binding, calcium channel activity, endopeptidase activity, protein binding Human PSEN2 BHF-UCL UniProtKB {GO:0005515=PMID:10748169, GO:0030018=GO_REF:0000033, GO:0031594=GO_REF:0000033, GO:0007220=Reactome:REACT_691, GO:0042640=GO_REF:0000019, GO:0001756=GO_REF:0000019, GO:0048538=GO_REF:0000019, GO:0015031=GO_REF:0000019, GO:0005765=GO_REF:0000033, GO:0060048=GO_REF:0000019, GO:0007219=Reactome:REACT_118862, GO:0016485=PMID:15274632, GO:0048167=GO_REF:0000019, GO:0007176=GO_REF:0000019, GO:0043025=GO_REF:0000033, GO:0007613=GO_REF:0000019, GO:0006509=PMID:15274632, GO:0005938=GO_REF:0000033, GO:0005813=PMID:9298903, GO:0005794=PMID:15274632, GO:0001708=GO_REF:0000019, GO:0048286=GO_REF:0000019, GO:0009986=GO_REF:0000033, GO:0032469=GO_REF:0000019, GO:0043393=GO_REF:0000019, GO:0043085=PMID:15274632, GO:0043234=PMID:9632714, GO:0002573=GO_REF:0000019, GO:0004175=GO_REF:0000033, GO:0005887=PMID:15274632, GO:0005789=GO_REF:0000039, GO:0000776=PMID:9298903, GO:0045121=GO_REF:0000033, GO:0044267=GO_REF:0000019, GO:0050852=GO_REF:0000019, GO:0030424=GO_REF:0000033, GO:0048471=GO_REF:0000033, GO:0005886=Reactome:REACT_160171, GO:0031293=Reactome:REACT_13443, GO:0005783=PMID:15274632, GO:0005743=GO_REF:0000033, GO:0005637=PMID:9298903, GO:0030326=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0030426=GO_REF:0000033, GO:0040011=GO_REF:0000019, GO:0035556=GO_REF:0000002, GO:0016324=GO_REF:0000033, GO:0043198=GO_REF:0000033, GO:0002244=GO_REF:0000019, GO:0021904=GO_REF:0000019, GO:0006816=GO_REF:0000033, GO:0002286=GO_REF:0000019, GO:0042987=PMID:15274632, GO:0001666=GO_REF:0000019, GO:0048011=Reactome:REACT_13776, GO:0043065=GO_REF:0000019, GO:0006915=Reactome:REACT_13643, GO:0050820=GO_REF:0000019, GO:0097190=Reactome:REACT_13720, GO:0050435=GO_REF:0000033, GO:0048854=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0000139=GO_REF:0000039, GO:0035253=GO_REF:0000033, GO:0001933=GO_REF:0000019, GO:0030900=GO_REF:0000019, GO:0004190=GO_REF:0000002, GO:0016021=GO_REF:0000038} P49810 Presenilin-2 protein 20130128 {GO:0005515=IPI, GO:0030018=IBA, GO:0031594=IBA, GO:0007220=TAS, GO:0042640=IEA, GO:0001756=IEA, GO:0048538=IEA, GO:0015031=IEA, GO:0005765=IBA, GO:0060048=IEA, GO:0007219=TAS, GO:0016485=IDA, GO:0048167=IEA, GO:0007176=IEA, GO:0043025=IBA, GO:0007613=IEA, GO:0006509=IDA, GO:0005938=IBA, GO:0005813=IDA, GO:0005794=IDA, GO:0001708=IEA, GO:0048286=IEA, GO:0009986=IBA, GO:0032469=IEA, GO:0043393=IEA, GO:0043085=IDA, GO:0043234=IDA, GO:0002573=IEA, GO:0004175=IBA, GO:0005887=IDA, GO:0005789=IEA, GO:0000776=IDA, GO:0045121=IBA, GO:0044267=IEA, GO:0050852=IEA, GO:0030424=IBA, GO:0048471=IBA, GO:0005886=TAS, GO:0031293=TAS, GO:0005783=IDA, GO:0005743=IBA, GO:0005637=IDA, GO:0030326=IEA, GO:0005829=IEA, GO:0030426=IBA, GO:0040011=IEA, GO:0035556=IEA, GO:0016324=IBA, GO:0043198=IBA, GO:0002244=IEA, GO:0021904=IEA, GO:0006816=IBA, GO:0002286=IEA, GO:0042987=TAS, GO:0001666=IEA, GO:0048011=TAS, GO:0043065=IEA, GO:0006915=TAS, GO:0050820=IEA, GO:0097190=TAS, GO:0050435=IBA, GO:0048854=IEA, GO:0016020=IEA, GO:0000139=IEA, GO:0035253=IBA, GO:0001933=IEA, GO:0030900=IEA, GO:0004190=IEA, GO:0016021=IEA} Notch receptor processing, Notch signaling pathway, T cell activation involved in immune response, T cell receptor signaling pathway, amyloid precursor protein catabolic process, anagen, apoptotic process, apoptotic signaling pathway, beta-amyloid metabolic process, brain morphogenesis, calcium ion transport, cardiac muscle contraction, cell fate specification, cellular protein metabolic process, dorsal/ventral neural tube patterning, embryonic limb morphogenesis, endoplasmic reticulum calcium ion homeostasis, forebrain development, hematopoietic progenitor cell differentiation, intracellular signal transduction, locomotion, lung alveolus development, membrane protein ectodomain proteolysis, membrane protein intracellular domain proteolysis, memory, myeloid leukocyte differentiation, negative regulation of protein phosphorylation, neurotrophin TRK receptor signaling pathway, positive regulation of apoptotic process, positive regulation of catalytic activity, positive regulation of coagulation, protein processing, protein transport, regulation of epidermal growth factor-activated receptor activity, regulation of protein binding, regulation of synaptic plasticity, response to hypoxia, somitogenesis, thymus development Golgi apparatus, Golgi membrane, Z disc, apical plasma membrane, axon, cell cortex, cell surface, centrosome, ciliary rootlet, cytosol, dendritic shaft, endoplasmic reticulum, endoplasmic reticulum membrane, growth cone, integral to membrane, integral to plasma membrane, kinetochore, lysosomal membrane, membrane, membrane raft, mitochondrial inner membrane, neuromuscular junction, neuronal cell body, nuclear inner membrane, perinuclear region of cytoplasm, plasma membrane, protein complex aspartic-type endopeptidase activity, endopeptidase activity, protein binding Human UniProtKB:P30626 PSENEN IntAct UniProtKB {GO:0005515=PMID:16641999, GO:0042987=PMID:15274632, GO:0048011=Reactome:REACT_13776, GO:0007220=Reactome:REACT_691, GO:0005794=PMID:15274632, GO:0005886=Reactome:REACT_160171, GO:0031293=Reactome:REACT_13443, GO:0005783=PMID:15274632, GO:0006915=Reactome:REACT_13643, GO:0043085=PMID:15274632, GO:0097190=Reactome:REACT_13720, GO:0007219=Reactome:REACT_118862, GO:0016485=PMID:15274632, GO:0005887=PMID:15274632, GO:0032580=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0006509=PMID:15274632} Q9NZ42 Gamma-secretase subunit PEN-2 protein 20130415 {GO:0005515=IPI, GO:0042987=TAS, GO:0048011=TAS, GO:0007220=TAS, GO:0005794=IDA, GO:0005886=TAS, GO:0031293=TAS, GO:0005783=IDA, GO:0006915=TAS, GO:0043085=IDA, GO:0097190=TAS, GO:0007219=TAS, GO:0016485=IDA, GO:0005887=IDA, GO:0032580=IEA, GO:0005789=IEA, GO:0006509=IDA} Notch receptor processing, Notch signaling pathway, amyloid precursor protein catabolic process, apoptotic process, apoptotic signaling pathway, membrane protein ectodomain proteolysis, membrane protein intracellular domain proteolysis, neurotrophin TRK receptor signaling pathway, positive regulation of catalytic activity, protein processing Golgi apparatus, Golgi cisterna membrane, endoplasmic reticulum, endoplasmic reticulum membrane, integral to plasma membrane, plasma membrane protein binding Human UniProtKB:P49755 PSG1 PINC UniProtKB {GO:0007565=PMID:1572651, GO:0005576=GO_REF:0000039} P11464 Pregnancy-specific beta-1-glycoprotein 1 protein 20030904 {GO:0007565=TAS, GO:0005576=IEA} female pregnancy extracellular region Human PSG2 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0007565=PMID:3260773, GO:0016477=PMID:3260773, GO:0005576=GO_REF:0000039, GO:0005575=GO_REF:0000015} P11465 Pregnancy-specific beta-1-glycoprotein 2 protein 20061026 {GO:0003674=ND, GO:0007565=NAS, GO:0016477=NAS, GO:0005576=IEA, GO:0005575=ND} cell migration, female pregnancy cellular_component, extracellular region molecular_function Human PSG3 UniProtKB UniProtKB {GO:0007565=PMID:3265688, GO:0005576=GO_REF:0000029, GO:0006952=PMID:2341148} Q16557 Pregnancy-specific beta-1-glycoprotein 3 protein 20040727 {GO:0007565=TAS, GO:0005576=NAS, GO:0006952=TAS} defense response, female pregnancy extracellular region Human PSG5 IntAct UniProtKB {GO:0005515=PMID:21982860, GO:0007565=PMID:1690992, GO:0005576=GO_REF:0000039} Q15238 Pregnancy-specific beta-1-glycoprotein 5 protein 20130415 {GO:0005515=IPI, GO:0007565=TAS, GO:0005576=IEA} female pregnancy extracellular region protein binding Human UniProtKB:P35590 PSG9 PINC UniProtKB {GO:0007565=PMID:1690992, GO:0005576=GO_REF:0000039} Q00887 Pregnancy-specific beta-1-glycoprotein 9 protein 20030904 {GO:0007565=TAS, GO:0005576=IEA} female pregnancy extracellular region Human PSIP1 HPA UniProtKB {GO:0022415=Reactome:REACT_6266, GO:0006355=GO_REF:0000037, GO:0009408=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0035327=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037, GO:0005829=Reactome:REACT_9450, GO:0000395=PMID:9885563, GO:0097100=GO_REF:0000024, GO:0016032=Reactome:REACT_6256, GO:0005654=Reactome:REACT_9054, GO:0006979=GO_REF:0000024, GO:0075713=Reactome:REACT_8990} O75475 PC4 and SFRS1-interacting protein protein 20101115 {GO:0022415=TAS, GO:0006355=IEA, GO:0009408=ISS, GO:0005730=IDA, GO:0035327=ISS, GO:0005634=IDA, GO:0006351=IEA, GO:0005829=TAS, GO:0000395=IDA, GO:0097100=ISS, GO:0016032=TAS, GO:0005654=TAS, GO:0006979=ISS, GO:0075713=TAS} establishment of integrated proviral latency, mRNA 5'-splice site recognition, regulation of transcription, DNA-dependent, response to heat, response to oxidative stress, transcription, DNA-dependent, viral reproduction, viral reproductive process cytosol, nucleolus, nucleoplasm, nucleus, transcriptionally active chromatin supercoiled DNA binding NOT Human PSKH1 IntAct UniProtKB {GO:0005515=PMID:22939624, GO:0005794=GO_REF:0000039, GO:0016607=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0005815=GO_REF:0000039, GO:0004674=GO_REF:0000029, GO:0005789=GO_REF:0000039, GO:0006468=GO_REF:0000029, GO:0005575=GO_REF:0000015, GO:0005524=GO_REF:0000029} P11801 Serine/threonine-protein kinase H1 protein 20130415 {GO:0005515=IPI, GO:0005794=IEA, GO:0016607=IEA, GO:0005886=IEA, GO:0005815=IEA, GO:0004674=NAS, GO:0005789=IEA, GO:0006468=NAS, GO:0005575=ND, GO:0005524=NAS} protein phosphorylation Golgi apparatus, cellular_component, endoplasmic reticulum membrane, microtubule organizing center, nuclear speck, plasma membrane ATP binding, protein binding, protein serine/threonine kinase activity Human UniProtKB:P08238 PSKH2 UniProtKB UniProtKB {GO:0004674=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q96QS6 Serine/threonine-protein kinase H2 protein 20130413 {GO:0004674=IEA, GO:0005524=IEA} ATP binding, protein serine/threonine kinase activity Human UniProtKB-KW:KW-0067 PSMA1 HPA UniProtKB {GO:0005515=PMID:17292860, GO:0010467=Reactome:REACT_71, GO:0006511=GO_REF:0000002, GO:0002474=Reactome:REACT_75820, GO:0002862=GO_REF:0000019, GO:0003723=PMID:7681138, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_118617, GO:0004298=GO_REF:0000037, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000040, GO:0000082=Reactome:REACT_1783, GO:0051603=GO_REF:0000002, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0005813=GO_REF:0000052, GO:0005839=GO_REF:0000024, GO:0000502=PMID:8811196, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0005730=GO_REF:0000052, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0001530=GO_REF:0000019, GO:0019773=GO_REF:0000002, GO:0000075=Reactome:REACT_1538, GO:0002479=Reactome:REACT_111178, GO:0005654=Reactome:REACT_9034, GO:0000278=Reactome:REACT_152, GO:0005844=PMID:7681138, GO:0000090=Reactome:REACT_1275} P25786 Proteasome subunit alpha type-1 protein 20110516 {GO:0005515=IPI, GO:0010467=TAS, GO:0006511=IEA, GO:0002474=TAS, GO:0002862=IEA, GO:0003723=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0031145=TAS, GO:0005829=TAS, GO:0004298=IEA, GO:0000084=TAS, GO:0034641=TAS, GO:0005737=IEA, GO:0000082=TAS, GO:0051603=IEA, GO:0000087=TAS, GO:0016032=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0005813=IDA, GO:0005839=ISS, GO:0000502=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0005730=IDA, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0001530=IEA, GO:0019773=IEA, GO:0000075=TAS, GO:0002479=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0005844=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of inflammatory response to antigenic stimulus, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, proteolysis involved in cellular protein catabolic process, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, ubiquitin-dependent protein catabolic process, viral reproduction centrosome, cytoplasm, cytosol, nucleolus, nucleoplasm, nucleus, polysome, proteasome complex, proteasome core complex, proteasome core complex, alpha-subunit complex RNA binding, lipopolysaccharide binding, protein binding, threonine-type endopeptidase activity Human PSMA2 IntAct UniProtKB {GO:0005515=PMID:15887188, GO:0006511=GO_REF:0000002, GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0004298=GO_REF:0000037, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0000082=Reactome:REACT_1783, GO:0000932=GO_REF:0000024, GO:0051603=GO_REF:0000002, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0000502=PMID:8811196, GO:0005839=GO_REF:0000024, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0009615=PMID:16548883, GO:0051439=Reactome:REACT_6837, GO:0019773=GO_REF:0000002, GO:0004175=GO_REF:0000002, GO:0000075=Reactome:REACT_1538, GO:0002479=Reactome:REACT_111178, GO:0005654=Reactome:REACT_9034, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} P25787 Proteasome subunit alpha type-2 protein 20130415 {GO:0005515=IPI, GO:0006511=IEA, GO:0002474=TAS, GO:0010467=TAS, GO:0044281=TAS, GO:0031145=TAS, GO:0004298=IEA, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0000082=TAS, GO:0000932=ISS, GO:0051603=IEA, GO:0000087=TAS, GO:0016032=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0000502=TAS, GO:0005839=ISS, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0009615=IEP, GO:0051439=TAS, GO:0019773=IEA, GO:0004175=IEA, GO:0000075=TAS, GO:0002479=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, proteolysis involved in cellular protein catabolic process, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, response to virus, small molecule metabolic process, ubiquitin-dependent protein catabolic process, viral reproduction cytoplasmic mRNA processing body, cytosol, nucleoplasm, proteasome complex, proteasome core complex, proteasome core complex, alpha-subunit complex endopeptidase activity, protein binding, threonine-type endopeptidase activity Human UniProtKB:P60900 PSMA3 BHF-UCL UniProtKB {GO:0005515=PMID:12826010, GO:0010467=Reactome:REACT_71, GO:0006511=GO_REF:0000002, GO:0002474=Reactome:REACT_75820, GO:0005634=PMID:16130169, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0004298=GO_REF:0000037, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0000082=Reactome:REACT_1783, GO:0005737=PMID:16130169, GO:0051603=GO_REF:0000002, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0000502=PMID:8811196, GO:0005839=PMID:19208651, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0019773=GO_REF:0000002, GO:0004175=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0000075=Reactome:REACT_1538, GO:0002479=Reactome:REACT_111178, GO:0005654=Reactome:REACT_9034, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} P25788 Proteasome subunit alpha type-3 protein 20080306 {GO:0005515=IPI, GO:0010467=TAS, GO:0006511=IEA, GO:0002474=TAS, GO:0005634=TAS, GO:0044281=TAS, GO:0031145=TAS, GO:0004298=IEA, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0000082=TAS, GO:0005737=TAS, GO:0051603=IEA, GO:0000087=TAS, GO:0016032=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0000502=TAS, GO:0005839=IDA, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0019773=IEA, GO:0004175=IEA, GO:0019048=IEA, GO:0000075=TAS, GO:0002479=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, proteolysis involved in cellular protein catabolic process, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, ubiquitin-dependent protein catabolic process, viral reproduction, virus-host interaction cytoplasm, cytosol, nucleoplasm, nucleus, proteasome complex, proteasome core complex, proteasome core complex, alpha-subunit complex endopeptidase activity, protein binding, threonine-type endopeptidase activity Human UniProtKB:Q03014 PSMA4 IntAct UniProtKB {GO:0005515=PMID:14733938, GO:0006511=GO_REF:0000002, GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0005634=GO_REF:0000040, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0004298=GO_REF:0000037, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0000082=Reactome:REACT_1783, GO:0005737=GO_REF:0000040, GO:0000932=GO_REF:0000024, GO:0051603=GO_REF:0000002, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0000502=PMID:8811196, GO:0005839=GO_REF:0000024, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0019773=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0000075=Reactome:REACT_1538, GO:0002479=Reactome:REACT_111178, GO:0005654=Reactome:REACT_9034, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} P25789 Proteasome subunit alpha type-4 protein 20130415 {GO:0005515=IPI, GO:0006511=IEA, GO:0002474=TAS, GO:0010467=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0031145=TAS, GO:0004298=IEA, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0000082=TAS, GO:0005737=IEA, GO:0000932=ISS, GO:0051603=IEA, GO:0000087=TAS, GO:0016032=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0000502=TAS, GO:0005839=ISS, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0019773=IEA, GO:0019048=IEA, GO:0000075=TAS, GO:0002479=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, proteolysis involved in cellular protein catabolic process, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, ubiquitin-dependent protein catabolic process, viral reproduction, virus-host interaction cytoplasm, cytoplasmic mRNA processing body, cytosol, nucleoplasm, nucleus, proteasome complex, proteasome core complex, proteasome core complex, alpha-subunit complex protein binding, threonine-type endopeptidase activity Human UniProtKB:P25787 PSMA5 HPA UniProtKB {GO:0005515=PMID:16251969, GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0004298=GO_REF:0000037, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000052, GO:0000082=Reactome:REACT_1783, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0000502=PMID:8811196, GO:0005839=GO_REF:0000024, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0005730=GO_REF:0000052, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0019773=GO_REF:0000002, GO:0000075=Reactome:REACT_1538, GO:0002479=Reactome:REACT_111178, GO:0005654=Reactome:REACT_9034, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} P28066 Proteasome subunit alpha type-5 protein 20111111 {GO:0005515=IPI, GO:0002474=TAS, GO:0010467=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0031145=TAS, GO:0004298=IEA, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0005737=IDA, GO:0000082=TAS, GO:0000087=TAS, GO:0016032=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0000502=TAS, GO:0005839=ISS, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0005730=IDA, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0019773=IEA, GO:0000075=TAS, GO:0002479=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, viral reproduction cytoplasm, cytosol, nucleolus, nucleoplasm, nucleus, proteasome complex, proteasome core complex, proteasome core complex, alpha-subunit complex protein binding, threonine-type endopeptidase activity Human PSMA6 BHF-UCL UniProtKB {GO:0005515=PMID:16169070, GO:0010467=Reactome:REACT_71, GO:0006511=GO_REF:0000029, GO:0002474=Reactome:REACT_75820, GO:0003723=PMID:7681138, GO:0035639=PMID:7681138, GO:0005634=PMID:7681138, GO:0044281=Reactome:REACT_111217, GO:0030016=GO_REF:0000024, GO:0031145=Reactome:REACT_6871, GO:0030017=GO_REF:0000024, GO:0016363=GO_REF:0000024, GO:0004298=GO_REF:0000037, GO:0005829=Reactome:REACT_118617, GO:0005739=GO_REF:0000052, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000052, GO:0000082=Reactome:REACT_1783, GO:0051092=PMID:16845397, GO:0000932=GO_REF:0000024, GO:0051603=PMID:16845397, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0005839=GO_REF:0000024, GO:0051059=PMID:14743216, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0050727=PMID:16845397, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0019773=PMID:9096325, GO:0004175=PMID:7681138, GO:0000075=Reactome:REACT_1538, GO:0002479=Reactome:REACT_111178, GO:0005654=Reactome:REACT_9034, GO:0000278=Reactome:REACT_152, GO:0005844=PMID:7681138, GO:0000090=Reactome:REACT_1275} P60900 Proteasome subunit alpha type-6 protein 20110114 {GO:0005515=IPI, GO:0010467=TAS, GO:0006511=NAS, GO:0002474=TAS, GO:0003723=IDA, GO:0035639=NAS, GO:0005634=IDA, GO:0044281=TAS, GO:0030016=ISS, GO:0031145=TAS, GO:0030017=ISS, GO:0016363=ISS, GO:0004298=IEA, GO:0005829=TAS, GO:0005739=IDA, GO:0000084=TAS, GO:0034641=TAS, GO:0005737=IDA, GO:0000082=TAS, GO:0051092=IMP, GO:0000932=ISS, GO:0051603=IMP, GO:0000087=TAS, GO:0016032=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0005839=ISS, GO:0051059=IPI, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0050727=IC, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0019773=IDA, GO:0004175=NAS, GO:0000075=TAS, GO:0002479=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0005844=IDA, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of NF-kappaB transcription factor activity, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, proteolysis involved in cellular protein catabolic process, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of inflammatory response, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, ubiquitin-dependent protein catabolic process, viral reproduction cytoplasm, cytoplasmic mRNA processing body, cytosol, mitochondrion, myofibril, nuclear matrix, nucleoplasm, nucleus, polysome, proteasome core complex, proteasome core complex, alpha-subunit complex, sarcomere NF-kappaB binding, RNA binding, endopeptidase activity, protein binding, purine ribonucleoside triphosphate binding, threonine-type endopeptidase activity Human UniProtKB:Q9QUM9 PSMA7 InterPro UniProtKB {GO:0005515=PMID:21988832, GO:0006511=GO_REF:0000002, GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0042802=PMID:15225636, GO:0004298=GO_REF:0000002, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0000082=Reactome:REACT_1783, GO:0051603=GO_REF:0000002, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0000502=PMID:8811196, GO:0005839=GO_REF:0000024, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0019773=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0000075=Reactome:REACT_1538, GO:0002479=Reactome:REACT_111178, GO:0005654=Reactome:REACT_9034, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} Q5JXJ2 Proteasome subunit alpha type-7 protein 20130413 {GO:0005515=IPI, GO:0006511=IEA, GO:0002474=TAS, GO:0010467=TAS, GO:0044281=TAS, GO:0031145=TAS, GO:0042802=IPI, GO:0004298=IEA, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0000082=TAS, GO:0051603=IEA, GO:0000087=TAS, GO:0016032=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0000502=TAS, GO:0005839=ISS, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0019773=IEA, GO:0019048=IEA, GO:0000075=TAS, GO:0002479=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, proteolysis involved in cellular protein catabolic process, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, ubiquitin-dependent protein catabolic process, viral reproduction, virus-host interaction cytosol, nucleoplasm, proteasome complex, proteasome core complex, proteasome core complex, alpha-subunit complex identical protein binding, protein binding, threonine-type endopeptidase activity Human InterPro:IPR000426 PSMA8 Reactome UniProtKB {GO:0002474=Reactome:REACT_75820, GO:0006511=GO_REF:0000002, GO:0010467=Reactome:REACT_71, GO:0005634=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0004298=GO_REF:0000037, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051439=Reactome:REACT_6837, GO:0019773=GO_REF:0000002, GO:0004175=GO_REF:0000002, GO:0002479=Reactome:REACT_111178, GO:0000075=Reactome:REACT_1538, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} Q8TAA3 Proteasome subunit alpha type-7-like protein 20100909 {GO:0002474=TAS, GO:0006511=IEA, GO:0010467=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0031145=TAS, GO:0004298=IEA, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0000087=TAS, GO:0016032=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051439=TAS, GO:0019773=IEA, GO:0004175=IEA, GO:0002479=TAS, GO:0000075=TAS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, ubiquitin-dependent protein catabolic process, viral reproduction cytosol, nucleus, proteasome core complex, alpha-subunit complex endopeptidase activity, threonine-type endopeptidase activity Human PSMB1 IntAct UniProtKB {GO:0005515=PMID:20723761, GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_118617, GO:0004298=GO_REF:0000037, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0000082=Reactome:REACT_1783, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0005839=GO_REF:0000024, GO:0000502=PMID:8811196, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0042590=Reactome:REACT_111119, GO:0051437=Reactome:REACT_6821, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0019048=GO_REF:0000037, GO:0002479=Reactome:REACT_111178, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_6715, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} P20618 Proteasome subunit beta type-1 protein 20130415 {GO:0005515=IPI, GO:0002474=TAS, GO:0010467=TAS, GO:0044281=TAS, GO:0031145=TAS, GO:0005829=TAS, GO:0004298=IEA, GO:0000084=TAS, GO:0034641=TAS, GO:0000082=TAS, GO:0000087=TAS, GO:0016032=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0005839=ISS, GO:0000502=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0042590=TAS, GO:0051437=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0019048=IEA, GO:0002479=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, viral reproduction, virus-host interaction cytosol, nucleoplasm, proteasome complex, proteasome core complex protein binding, threonine-type endopeptidase activity Human UniProtKB:Q99436 PSMB10 Reactome UniProtKB {GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0004298=GO_REF:0000037, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0000082=Reactome:REACT_1783, GO:0042098=GO_REF:0000019, GO:0051603=GO_REF:0000002, GO:0006959=PMID:8666937, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0000502=PMID:9551082, GO:0005839=GO_REF:0000024, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0000902=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0000075=Reactome:REACT_1538, GO:0002479=Reactome:REACT_111178, GO:0005654=Reactome:REACT_9034, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} P40306 Proteasome subunit beta type-10 protein 20130213 {GO:0002474=TAS, GO:0010467=TAS, GO:0044281=TAS, GO:0031145=TAS, GO:0004298=IEA, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0000082=TAS, GO:0042098=IEA, GO:0051603=IEA, GO:0006959=TAS, GO:0000087=TAS, GO:0016032=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0000502=TAS, GO:0005839=ISS, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0000902=IEA, GO:0019048=IEA, GO:0000075=TAS, GO:0002479=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, T cell proliferation, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cell morphogenesis, cellular nitrogen compound metabolic process, gene expression, humoral immune response, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, proteolysis involved in cellular protein catabolic process, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, viral reproduction, virus-host interaction cytosol, nucleoplasm, proteasome complex, proteasome core complex threonine-type endopeptidase activity Human PSMB2 HPA UniProtKB {GO:0014070=GO_REF:0000019, GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0004298=GO_REF:0000037, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0000082=Reactome:REACT_1783, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0005839=GO_REF:0000024, GO:0000502=PMID:8811196, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0005730=GO_REF:0000052, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0010243=GO_REF:0000019, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0019048=GO_REF:0000037, GO:0000075=Reactome:REACT_1538, GO:0002479=Reactome:REACT_111178, GO:0005654=Reactome:REACT_9034, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} P49721 Proteasome subunit beta type-2 protein 20111111 {GO:0014070=IEA, GO:0002474=TAS, GO:0010467=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0031145=TAS, GO:0004298=IEA, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0000082=TAS, GO:0000087=TAS, GO:0016032=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0005839=ISS, GO:0000502=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0005730=IDA, GO:0051437=TAS, GO:0042590=TAS, GO:0010243=IEA, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0019048=IEA, GO:0000075=TAS, GO:0002479=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, response to organic cyclic compound, response to organic nitrogen, small molecule metabolic process, viral reproduction, virus-host interaction cytosol, nucleolus, nucleoplasm, nucleus, proteasome complex, proteasome core complex threonine-type endopeptidase activity NOT Human PSMB3 Reactome UniProtKB {GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0005634=GO_REF:0000038, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0004298=GO_REF:0000037, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0000082=Reactome:REACT_1783, GO:0051603=GO_REF:0000002, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0000502=PMID:8811196, GO:0005839=GO_REF:0000024, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0019048=GO_REF:0000037, GO:0000075=Reactome:REACT_1538, GO:0002479=Reactome:REACT_111178, GO:0005654=Reactome:REACT_9034, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} P49720 Proteasome subunit beta type-3 protein 20130213 {GO:0002474=TAS, GO:0010467=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0031145=TAS, GO:0004298=IEA, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0000082=TAS, GO:0051603=IEA, GO:0000087=TAS, GO:0016032=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0000502=TAS, GO:0005839=ISS, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0019048=IEA, GO:0000075=TAS, GO:0002479=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, proteolysis involved in cellular protein catabolic process, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, viral reproduction, virus-host interaction cytosol, nucleoplasm, nucleus, proteasome complex, proteasome core complex threonine-type endopeptidase activity Human PSMB4 Reactome UniProtKB {GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0002862=GO_REF:0000019, GO:0005634=PMID:16130169, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0004298=GO_REF:0000037, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0000082=Reactome:REACT_1783, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0000502=PMID:8811196, GO:0005839=GO_REF:0000024, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0001530=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0000075=Reactome:REACT_1538, GO:0002479=Reactome:REACT_111178, GO:0005654=Reactome:REACT_9034, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} P28070 Proteasome subunit beta type-4 protein 20130213 {GO:0002474=TAS, GO:0010467=TAS, GO:0002862=IEA, GO:0005634=TAS, GO:0044281=TAS, GO:0031145=TAS, GO:0004298=IEA, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0000082=TAS, GO:0000087=TAS, GO:0016032=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0000502=TAS, GO:0005839=ISS, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0001530=IEA, GO:0019048=IEA, GO:0000075=TAS, GO:0002479=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of inflammatory response to antigenic stimulus, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, viral reproduction, virus-host interaction cytosol, nucleoplasm, nucleus, proteasome complex, proteasome core complex lipopolysaccharide binding, threonine-type endopeptidase activity Human PSMB5 IntAct UniProtKB {GO:0005515=PMID:20723761, GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0005634=GO_REF:0000038, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0004298=GO_REF:0000037, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0000082=Reactome:REACT_1783, GO:0051603=GO_REF:0000002, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0006979=GO_REF:0000019, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0000502=PMID:8811196, GO:0005839=GO_REF:0000024, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0019048=GO_REF:0000037, GO:0000075=Reactome:REACT_1538, GO:0002479=Reactome:REACT_111178, GO:0005654=Reactome:REACT_9034, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} P28074 Proteasome subunit beta type-5 protein 20130415 {GO:0005515=IPI, GO:0002474=TAS, GO:0010467=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0031145=TAS, GO:0004298=IEA, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0000082=TAS, GO:0051603=IEA, GO:0000087=TAS, GO:0016032=TAS, GO:0006979=IEA, GO:0006977=TAS, GO:0000209=TAS, GO:0000502=TAS, GO:0005839=ISS, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0019048=IEA, GO:0000075=TAS, GO:0002479=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, proteolysis involved in cellular protein catabolic process, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, response to oxidative stress, small molecule metabolic process, viral reproduction, virus-host interaction cytosol, nucleoplasm, nucleus, proteasome complex, proteasome core complex protein binding, threonine-type endopeptidase activity Human UniProtKB:Q99436 PSMB6 Reactome UniProtKB {GO:0006511=GO_REF:0000029, GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0005634=GO_REF:0000038, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0004298=GO_REF:0000037, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0000082=Reactome:REACT_1783, GO:0051603=GO_REF:0000002, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0005839=GO_REF:0000024, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0004175=PMID:8066462, GO:0019048=GO_REF:0000037, GO:0000075=Reactome:REACT_1538, GO:0002479=Reactome:REACT_111178, GO:0005654=Reactome:REACT_9034, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} P28072 Proteasome subunit beta type-6 protein 20130213 {GO:0006511=NAS, GO:0002474=TAS, GO:0010467=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0031145=TAS, GO:0004298=IEA, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0000082=TAS, GO:0051603=IEA, GO:0000087=TAS, GO:0016032=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0005839=ISS, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0004175=NAS, GO:0019048=IEA, GO:0000075=TAS, GO:0002479=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, proteolysis involved in cellular protein catabolic process, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, ubiquitin-dependent protein catabolic process, viral reproduction, virus-host interaction cytosol, nucleoplasm, nucleus, proteasome core complex endopeptidase activity, threonine-type endopeptidase activity Human PSMB7 IntAct UniProtKB {GO:0005515=PMID:20723761, GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0005634=GO_REF:0000040, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0004298=GO_REF:0000037, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0000082=Reactome:REACT_1783, GO:0005737=GO_REF:0000040, GO:0051603=GO_REF:0000002, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0000502=PMID:8811196, GO:0005839=GO_REF:0000024, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0019048=GO_REF:0000037, GO:0000075=Reactome:REACT_1538, GO:0002479=Reactome:REACT_111178, GO:0005654=Reactome:REACT_9034, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} Q99436 Proteasome subunit beta type-7 protein 20130415 {GO:0005515=IPI, GO:0002474=TAS, GO:0010467=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0031145=TAS, GO:0004298=IEA, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0000082=TAS, GO:0005737=IEA, GO:0051603=IEA, GO:0000087=TAS, GO:0016032=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0000502=TAS, GO:0005839=ISS, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0019048=IEA, GO:0000075=TAS, GO:0002479=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, proteolysis involved in cellular protein catabolic process, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, viral reproduction, virus-host interaction cytoplasm, cytosol, nucleoplasm, nucleus, proteasome complex, proteasome core complex protein binding, threonine-type endopeptidase activity Human UniProtKB:P28074 PSMB8 InterPro UniProtKB {GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0019221=Reactome:REACT_25229, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0004298=GO_REF:0000002, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0000082=Reactome:REACT_1783, GO:0060337=Reactome:REACT_25162, GO:0051603=GO_REF:0000002, GO:0000087=Reactome:REACT_910, GO:0045444=PMID:21881205, GO:0016032=Reactome:REACT_6185, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0000502=PMID:8666937, GO:0005839=GO_REF:0000002, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0019048=GO_REF:0000037, GO:0002479=Reactome:REACT_111178, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_25192, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} Q5JNW7 Proteasome subunit beta type-8 protein 20130413 {GO:0002474=TAS, GO:0010467=TAS, GO:0019221=TAS, GO:0044281=TAS, GO:0031145=TAS, GO:0004298=IEA, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0000082=TAS, GO:0060337=TAS, GO:0051603=IEA, GO:0000087=TAS, GO:0045444=IMP, GO:0016032=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0000502=TAS, GO:0005839=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0019048=IEA, GO:0002479=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, cytokine-mediated signaling pathway, fat cell differentiation, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, proteolysis involved in cellular protein catabolic process, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, type I interferon-mediated signaling pathway, viral reproduction, virus-host interaction cytosol, nucleoplasm, proteasome complex, proteasome core complex threonine-type endopeptidase activity Human InterPro:IPR001353 PSMB9 IntAct UniProtKB {GO:0005515=PMID:20723761, GO:0010467=Reactome:REACT_71, GO:0002474=Reactome:REACT_75820, GO:0005634=GO_REF:0000040, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_118617, GO:0004298=GO_REF:0000037, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000040, GO:0000082=Reactome:REACT_1783, GO:0019882=GO_REF:0000019, GO:0051603=GO_REF:0000002, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0000502=PMID:8666937, GO:0005839=GO_REF:0000024, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0042590=Reactome:REACT_111119, GO:0051437=Reactome:REACT_6821, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0019048=GO_REF:0000037, GO:0002479=Reactome:REACT_111178, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9034, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} P28065 Proteasome subunit beta type-9 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0002474=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0031145=TAS, GO:0005829=TAS, GO:0004298=IEA, GO:0000084=TAS, GO:0034641=TAS, GO:0005737=IEA, GO:0000082=TAS, GO:0019882=IEA, GO:0051603=IEA, GO:0000087=TAS, GO:0016032=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0000502=TAS, GO:0005839=ISS, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0042590=TAS, GO:0051437=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0019048=IEA, GO:0002479=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, proteolysis involved in cellular protein catabolic process, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, viral reproduction, virus-host interaction cytoplasm, cytosol, nucleoplasm, nucleus, proteasome complex, proteasome core complex protein binding, threonine-type endopeptidase activity Human UniProtKB:Q99436 PSMC1 GOC UniProtKB {GO:0005515=PMID:9452483, GO:0010467=Reactome:REACT_71, GO:0002474=Reactome:REACT_75820, GO:0006200=PMID:1429620, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0030163=GO_REF:0000002, GO:0000082=Reactome:REACT_1783, GO:0005737=GO_REF:0000052, GO:0000087=Reactome:REACT_910, GO:0006508=GO_REF:0000038, GO:0016032=Reactome:REACT_6185, GO:0016887=PMID:1429620, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0000502=PMID:8811196, GO:0017111=GO_REF:0000002, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0005730=GO_REF:0000052, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0005524=GO_REF:0000037, GO:0051439=Reactome:REACT_6837, GO:0000075=Reactome:REACT_1538, GO:0002479=Reactome:REACT_111178, GO:0008233=GO_REF:0000038, GO:0005654=Reactome:REACT_9034, GO:0022624=GO_REF:0000024, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} P62191 26S protease regulatory subunit 4 protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0002474=TAS, GO:0006200=ISS, GO:0005634=IDA, GO:0044281=TAS, GO:0031145=TAS, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0030163=IEA, GO:0000082=TAS, GO:0005737=IDA, GO:0000087=TAS, GO:0006508=IEA, GO:0016032=TAS, GO:0016887=ISS, GO:0006977=TAS, GO:0000209=TAS, GO:0000502=NAS, GO:0017111=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0005730=IDA, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0005524=IEA, GO:0051439=TAS, GO:0000075=TAS, GO:0002479=TAS, GO:0008233=IEA, GO:0005654=TAS, GO:0022624=ISS, GO:0000278=TAS, GO:0000090=TAS} ATP catabolic process, DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein catabolic process, protein polyubiquitination, proteolysis, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, viral reproduction cytoplasm, cytosol, nucleolus, nucleoplasm, nucleus, proteasome accessory complex, proteasome complex ATP binding, ATPase activity, nucleoside-triphosphatase activity, peptidase activity, protein binding Human UniProtKB:P35998 PSMC2 GOC UniProtKB {GO:0005515=PMID:22901813, GO:0010467=Reactome:REACT_71, GO:0006511=PMID:9295362, GO:0002474=Reactome:REACT_75820, GO:0006200=PMID:9295362, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_118617, GO:0005739=GO_REF:0000052, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0030163=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0000082=Reactome:REACT_1783, GO:0000932=GO_REF:0000024, GO:0000087=Reactome:REACT_910, GO:0006508=GO_REF:0000038, GO:0016032=Reactome:REACT_6185, GO:0016887=PMID:9295362, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0017111=GO_REF:0000002, GO:0000502=PMID:9295362, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0005730=GO_REF:0000052, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0005524=GO_REF:0000037, GO:0051439=Reactome:REACT_6837, GO:0019048=GO_REF:0000037, GO:0000075=Reactome:REACT_1538, GO:0002479=Reactome:REACT_111178, GO:0022624=GO_REF:0000024, GO:0008233=GO_REF:0000038, GO:0005654=Reactome:REACT_9034, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} P35998 26S protease regulatory subunit 7 protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0006511=IDA, GO:0002474=TAS, GO:0006200=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0031145=TAS, GO:0005829=TAS, GO:0005739=IDA, GO:0000084=TAS, GO:0034641=TAS, GO:0030163=IEA, GO:0005737=IDA, GO:0000082=TAS, GO:0000932=ISS, GO:0000087=TAS, GO:0006508=IEA, GO:0016032=TAS, GO:0016887=IDA, GO:0006977=TAS, GO:0000209=TAS, GO:0017111=IEA, GO:0000502=IDA, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0005730=IDA, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0005524=IEA, GO:0051439=TAS, GO:0019048=IEA, GO:0000075=TAS, GO:0002479=TAS, GO:0022624=ISS, GO:0008233=IEA, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS} ATP catabolic process, DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein catabolic process, protein polyubiquitination, proteolysis, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, ubiquitin-dependent protein catabolic process, viral reproduction, virus-host interaction cytoplasm, cytoplasmic mRNA processing body, cytosol, mitochondrion, nucleolus, nucleoplasm, nucleus, proteasome accessory complex, proteasome complex ATP binding, ATPase activity, nucleoside-triphosphatase activity, peptidase activity, protein binding Human PSMC3 GOC UniProtKB {GO:0005515=PMID:19490896, GO:0010467=Reactome:REACT_71, GO:0002474=Reactome:REACT_75820, GO:0048471=GO_REF:0000019, GO:0006200=PMID:1429620, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0030163=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0000082=Reactome:REACT_1783, GO:0000932=GO_REF:0000024, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0016887=PMID:1429620, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0017111=GO_REF:0000002, GO:0000502=PMID:8811196, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0003714=PMID:2194290, GO:0003713=PMID:8419915, GO:0001824=GO_REF:0000019, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0005524=GO_REF:0000037, GO:0051439=Reactome:REACT_6837, GO:0019048=GO_REF:0000037, GO:0000075=Reactome:REACT_1538, GO:0002479=Reactome:REACT_111178, GO:0022624=GO_REF:0000024, GO:0005654=Reactome:REACT_9034, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} P17980 26S protease regulatory subunit 6A protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0002474=TAS, GO:0048471=IEA, GO:0006200=ISS, GO:0005634=IDA, GO:0044281=TAS, GO:0031145=TAS, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0030163=IEA, GO:0005737=IDA, GO:0000082=TAS, GO:0000932=ISS, GO:0000087=TAS, GO:0016032=TAS, GO:0016887=ISS, GO:0006977=TAS, GO:0000209=TAS, GO:0017111=IEA, GO:0000502=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0003714=TAS, GO:0003713=TAS, GO:0001824=IEA, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0005524=IEA, GO:0051439=TAS, GO:0019048=IEA, GO:0000075=TAS, GO:0002479=TAS, GO:0022624=ISS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS} ATP catabolic process, DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, blastocyst development, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein catabolic process, protein polyubiquitination, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, viral reproduction, virus-host interaction cytoplasm, cytoplasmic mRNA processing body, cytosol, nucleoplasm, nucleus, perinuclear region of cytoplasm, proteasome accessory complex, proteasome complex ATP binding, ATPase activity, nucleoside-triphosphatase activity, protein binding, transcription coactivator activity, transcription corepressor activity Human UniProtKB:P35998 PSMC3IP UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0030374=PMID:21963259, GO:0007126=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006310=GO_REF:0000037, GO:0005575=GO_REF:0000015, GO:0003677=GO_REF:0000037} Q9P2W1 Homologous-pairing protein 2 homolog protein 20111123 {GO:0008150=ND, GO:0030374=IMP, GO:0007126=IEA, GO:0005634=IEA, GO:0006310=IEA, GO:0005575=ND, GO:0003677=IEA} DNA recombination, biological_process, meiosis cellular_component, nucleus DNA binding, ligand-dependent nuclear receptor transcription coactivator activity Human PSMC4 GOC UniProtKB {GO:0005515=PMID:21988832, GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0006200=PMID:9473509, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_118617, GO:0005739=GO_REF:0000052, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000052, GO:0000082=Reactome:REACT_1783, GO:0000087=Reactome:REACT_910, GO:0006508=PMID:8603043, GO:0016032=Reactome:REACT_6185, GO:0016887=PMID:9473509, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0000502=PMID:8603043, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0001824=GO_REF:0000019, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0005730=GO_REF:0000052, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0005524=GO_REF:0000037, GO:0051439=Reactome:REACT_6837, GO:0000075=Reactome:REACT_1538, GO:0002479=Reactome:REACT_111178, GO:0022624=GO_REF:0000024, GO:0005654=Reactome:REACT_9034, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} P43686 26S protease regulatory subunit 6B protein 20130413 {GO:0005515=IPI, GO:0002474=TAS, GO:0010467=TAS, GO:0006200=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0031145=TAS, GO:0005829=TAS, GO:0005739=IDA, GO:0000084=TAS, GO:0034641=TAS, GO:0005737=IDA, GO:0000082=TAS, GO:0000087=TAS, GO:0006508=TAS, GO:0016032=TAS, GO:0016887=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0000502=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0001824=IEA, GO:0051437=TAS, GO:0042590=TAS, GO:0005730=IDA, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0005524=IEA, GO:0051439=TAS, GO:0000075=TAS, GO:0002479=TAS, GO:0022624=ISS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS} ATP catabolic process, DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, blastocyst development, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, proteolysis, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, viral reproduction cytoplasm, cytosol, mitochondrion, nucleolus, nucleoplasm, nucleus, proteasome accessory complex, proteasome complex ATP binding, ATPase activity, protein binding Human PSMC5 HPA UniProtKB {GO:0005515=PMID:20178748, GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0031595=GO_REF:0000019, GO:0006366=PMID:7870181, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0043069=PMID:16432160, GO:0000082=Reactome:REACT_1783, GO:0005737=GO_REF:0000052, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0016887=PMID:1429620, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0003712=PMID:7870181, GO:0000502=PMID:9464850, GO:0017111=GO_REF:0000002, GO:0031531=PMID:7870181, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0005730=GO_REF:0000052, GO:0042590=Reactome:REACT_111119, GO:0005102=GO_REF:0000019, GO:0051437=Reactome:REACT_6821, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0031410=PMID:15885686, GO:0005524=GO_REF:0000037, GO:0051439=Reactome:REACT_6837, GO:0000075=Reactome:REACT_1538, GO:0017025=GO_REF:0000019, GO:0002479=Reactome:REACT_111178, GO:0022624=GO_REF:0000024, GO:0005654=Reactome:REACT_9034, GO:0043161=PMID:12110588, GO:0000278=Reactome:REACT_152, GO:0045893=PMID:7870181, GO:0000090=Reactome:REACT_1275, GO:0045892=GO_REF:0000019, GO:0008134=PMID:10816420} P62195 26S protease regulatory subunit 8 protein 20090616 {GO:0005515=IPI, GO:0002474=TAS, GO:0010467=TAS, GO:0031595=IEA, GO:0006366=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0031145=TAS, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0043069=NAS, GO:0000082=TAS, GO:0005737=IDA, GO:0000087=TAS, GO:0016032=TAS, GO:0016887=ISS, GO:0006977=TAS, GO:0000209=TAS, GO:0003712=TAS, GO:0000502=IDA, GO:0017111=IEA, GO:0031531=IPI, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0005730=IDA, GO:0042590=TAS, GO:0005102=IEA, GO:0051437=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0031410=IDA, GO:0005524=IEA, GO:0051439=TAS, GO:0000075=TAS, GO:0017025=IEA, GO:0002479=TAS, GO:0022624=ISS, GO:0005654=TAS, GO:0043161=IDA, GO:0000278=TAS, GO:0045893=NAS, GO:0000090=TAS, GO:0045892=IEA, GO:0008134=IPI} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of programmed cell death, negative regulation of transcription, DNA-dependent, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of transcription, DNA-dependent, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, proteasomal ubiquitin-dependent protein catabolic process, protein polyubiquitination, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, transcription from RNA polymerase II promoter, viral reproduction cytoplasm, cytoplasmic vesicle, cytosol, nuclear proteasome complex, nucleolus, nucleoplasm, nucleus, proteasome accessory complex, proteasome complex ATP binding, ATPase activity, TBP-class protein binding, nucleoside-triphosphatase activity, protein binding, receptor binding, thyrotropin-releasing hormone receptor binding, transcription cofactor activity, transcription factor binding Human PSMC6 GOC UniProtKB {GO:0005515=PMID:19490896, GO:0010467=Reactome:REACT_71, GO:0006511=PMID:9464850, GO:0002474=Reactome:REACT_75820, GO:0006200=PMID:9464850, GO:0005886=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0000082=Reactome:REACT_1783, GO:0005737=GO_REF:0000052, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0030674=PMID:11590019, GO:0016887=PMID:9464850, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0000502=PMID:9464850, GO:0017111=GO_REF:0000002, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0005730=GO_REF:0000052, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0005524=GO_REF:0000037, GO:0051439=Reactome:REACT_6837, GO:0000075=Reactome:REACT_1538, GO:0002479=Reactome:REACT_111178, GO:0022624=GO_REF:0000024, GO:0005654=Reactome:REACT_9034, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} P62333 26S protease regulatory subunit 10B protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0006511=IC, GO:0002474=TAS, GO:0006200=TAS, GO:0005886=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0031145=TAS, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0000082=TAS, GO:0005737=IDA, GO:0000087=TAS, GO:0016032=TAS, GO:0030674=NAS, GO:0016887=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0000502=IDA, GO:0017111=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0005730=IDA, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0005524=IEA, GO:0051439=TAS, GO:0000075=TAS, GO:0002479=TAS, GO:0022624=ISS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS} ATP catabolic process, DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, ubiquitin-dependent protein catabolic process, viral reproduction cytoplasm, cytosol, nucleolus, nucleoplasm, nucleus, plasma membrane, proteasome accessory complex, proteasome complex ATP binding, ATPase activity, nucleoside-triphosphatase activity, protein binding, protein binding, bridging Human PSMD1 Reactome UniProtKB {GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0000082=Reactome:REACT_1783, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0030234=GO_REF:0000002, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0000502=PMID:8811196, GO:0005838=PMID:8816993, GO:0042176=GO_REF:0000002, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0000075=Reactome:REACT_1538, GO:0002479=Reactome:REACT_111178, GO:0005654=Reactome:REACT_9034, GO:0022624=GO_REF:0000024, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} Q99460 26S proteasome non-ATPase regulatory subunit 1 protein 20130213 {GO:0002474=TAS, GO:0010467=TAS, GO:0044281=TAS, GO:0031145=TAS, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0000082=TAS, GO:0000087=TAS, GO:0016032=TAS, GO:0030234=IEA, GO:0006977=TAS, GO:0000209=TAS, GO:0000502=TAS, GO:0005838=TAS, GO:0042176=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0000075=TAS, GO:0002479=TAS, GO:0005654=TAS, GO:0022624=ISS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of protein catabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, viral reproduction cytosol, nucleoplasm, proteasome accessory complex, proteasome complex, proteasome regulatory particle enzyme regulator activity Human PSMD10 HPA UniProtKB {GO:0005515=PMID:21988832, GO:0010467=Reactome:REACT_71, GO:0002474=Reactome:REACT_75820, GO:0030307=PMID:10613832, GO:0032436=PMID:10613832, GO:0045737=PMID:11900540, GO:0005634=PMID:18040287, GO:0044281=Reactome:REACT_111217, GO:0015629=GO_REF:0000052, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_118617, GO:0043409=PMID:19729910, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000052, GO:0000082=Reactome:REACT_1783, GO:0090201=PMID:19729910, GO:0000087=Reactome:REACT_910, GO:0031398=PMID:16023600, GO:0016032=Reactome:REACT_6185, GO:0045111=GO_REF:0000052, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0043066=PMID:16023600, GO:0000502=PMID:8811196, GO:0005838=PMID:9714768, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0007253=PMID:18040287, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0032088=PMID:18040287, GO:0051436=Reactome:REACT_6785, GO:0000122=PMID:16023600, GO:0051439=Reactome:REACT_6837, GO:0008540=PMID:19490896, GO:0043518=PMID:16023600, GO:0000075=Reactome:REACT_1538, GO:0002479=Reactome:REACT_111178, GO:0005654=Reactome:REACT_9034, GO:0070682=PMID:19490896, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0008134=PMID:18040287} O75832 26S proteasome non-ATPase regulatory subunit 10 protein 20080818 {GO:0005515=IPI, GO:0010467=TAS, GO:0002474=TAS, GO:0030307=IDA, GO:0032436=TAS, GO:0045737=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0015629=IDA, GO:0031145=TAS, GO:0005829=TAS, GO:0043409=IMP, GO:0000084=TAS, GO:0034641=TAS, GO:0005737=IDA, GO:0000082=TAS, GO:0090201=IMP, GO:0000087=TAS, GO:0031398=IMP, GO:0016032=TAS, GO:0045111=IDA, GO:0006977=TAS, GO:0000209=TAS, GO:0043066=IDA, GO:0000502=TAS, GO:0005838=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0007253=IDA, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0032088=IDA, GO:0051436=TAS, GO:0000122=IDA, GO:0051439=TAS, GO:0008540=IDA, GO:0043518=IDA, GO:0000075=TAS, GO:0002479=TAS, GO:0005654=TAS, GO:0070682=IMP, GO:0000278=TAS, GO:0000090=TAS, GO:0008134=IPI} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, cytoplasmic sequestering of NF-kappaB, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of DNA damage response, signal transduction by p53 class mediator, negative regulation of MAPK cascade, negative regulation of NF-kappaB transcription factor activity, negative regulation of apoptotic process, negative regulation of release of cytochrome c from mitochondria, negative regulation of transcription from RNA polymerase II promoter, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of cell growth, positive regulation of cyclin-dependent protein kinase activity, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of protein ubiquitination, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, proteasome regulatory particle assembly, protein polyubiquitination, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, viral reproduction actin cytoskeleton, cytoplasm, cytosol, intermediate filament cytoskeleton, nucleoplasm, nucleus, proteasome complex, proteasome regulatory particle, proteasome regulatory particle, base subcomplex protein binding, transcription factor binding Human PSMD11 Reactome UniProtKB {GO:0002474=Reactome:REACT_75820, GO:0006511=PMID:22972301, GO:0010467=Reactome:REACT_71, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0043248=PMID:22972301, GO:0034641=Reactome:REACT_13, GO:0000082=Reactome:REACT_1783, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0000502=PMID:9119060, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0048863=PMID:22972301, GO:0000075=Reactome:REACT_1538, GO:0002479=Reactome:REACT_111178, GO:0022624=PMID:22972301, GO:0005654=Reactome:REACT_9034, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} O00231 26S proteasome non-ATPase regulatory subunit 11 protein 20130213 {GO:0002474=TAS, GO:0006511=IMP, GO:0010467=TAS, GO:0044281=TAS, GO:0031145=TAS, GO:0005829=TAS, GO:0000084=TAS, GO:0043248=IMP, GO:0034641=TAS, GO:0000082=TAS, GO:0000087=TAS, GO:0016032=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0000502=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0048863=IMP, GO:0000075=TAS, GO:0002479=TAS, GO:0022624=IDA, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, proteasome assembly, protein polyubiquitination, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, stem cell differentiation, ubiquitin-dependent protein catabolic process, viral reproduction cytosol, nucleoplasm, proteasome accessory complex, proteasome complex Human PSMD12 Reactome UniProtKB {GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0000082=Reactome:REACT_1783, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0005838=PMID:9426256, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0002479=Reactome:REACT_111178, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9034, GO:0022624=GO_REF:0000024, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} O00232 26S proteasome non-ATPase regulatory subunit 12 protein 20130213 {GO:0002474=TAS, GO:0010467=TAS, GO:0044281=TAS, GO:0031145=TAS, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0000082=TAS, GO:0000087=TAS, GO:0016032=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0005838=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0002479=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0022624=ISS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, viral reproduction cytosol, nucleoplasm, proteasome accessory complex, proteasome regulatory particle Human PSMD13 Reactome UniProtKB {GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0000082=Reactome:REACT_1783, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0000502=PMID:8811196, GO:0005838=GO_REF:0000019, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0007127=GO_REF:0000019, GO:0002479=Reactome:REACT_111178, GO:0000075=Reactome:REACT_1538, GO:0022624=GO_REF:0000024, GO:0005654=Reactome:REACT_9034, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} Q9UNM6 26S proteasome non-ATPase regulatory subunit 13 protein 20130213 {GO:0002474=TAS, GO:0010467=TAS, GO:0044281=TAS, GO:0031145=TAS, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0000082=TAS, GO:0000087=TAS, GO:0016032=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0000502=TAS, GO:0005838=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0007127=IEA, GO:0002479=TAS, GO:0000075=TAS, GO:0022624=ISS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, meiosis I, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, viral reproduction cytosol, nucleoplasm, proteasome accessory complex, proteasome complex, proteasome regulatory particle Human PSMD14 GOC UniProtKB {GO:0002474=Reactome:REACT_75820, GO:0006511=PMID:9374539, GO:0010467=Reactome:REACT_71, GO:0044281=Reactome:REACT_111217, GO:0006303=PMID:22909820, GO:0031145=Reactome:REACT_6871, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_9035, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0000082=Reactome:REACT_1783, GO:0070536=PMID:22909820, GO:0000724=PMID:22909820, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0000502=PMID:19214193, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0061136=PMID:18162577, GO:0061133=PMID:18162577, GO:0010950=PMID:18162577, GO:0008541=PMID:22909820, GO:0070628=PMID:18162577, GO:0002479=Reactome:REACT_111178, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9034, GO:0022624=GO_REF:0000024, GO:0004221=PMID:22909820, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0008237=PMID:19214193} O00487 26S proteasome non-ATPase regulatory subunit 14 protein 20130413 {GO:0002474=TAS, GO:0006511=TAS, GO:0010467=TAS, GO:0044281=TAS, GO:0006303=IMP, GO:0031145=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0000082=TAS, GO:0070536=IMP, GO:0000724=IMP, GO:0000087=TAS, GO:0016032=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0000502=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0061136=IMP, GO:0061133=IMP, GO:0010950=IMP, GO:0008541=IMP, GO:0070628=IDA, GO:0002479=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0022624=ISS, GO:0004221=IMP, GO:0000278=TAS, GO:0000090=TAS, GO:0008237=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, double-strand break repair via homologous recombination, double-strand break repair via nonhomologous end joining, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of endopeptidase activity, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K63-linked deubiquitination, protein polyubiquitination, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of proteasomal protein catabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, ubiquitin-dependent protein catabolic process, viral reproduction cytosol, nucleoplasm, proteasome accessory complex, proteasome complex, proteasome regulatory particle, lid subcomplex endopeptidase activator activity, metal ion binding, metallopeptidase activity, proteasome binding, ubiquitin thiolesterase activity Human PSMD2 IntAct UniProtKB {GO:0005515=PMID:22901813, GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0000082=Reactome:REACT_1783, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0030234=GO_REF:0000002, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0000502=PMID:8811196, GO:0005838=PMID:8774743, GO:0042176=GO_REF:0000002, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0000075=Reactome:REACT_1538, GO:0002479=Reactome:REACT_111178, GO:0005654=Reactome:REACT_9034, GO:0022624=GO_REF:0000024, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} Q13200 26S proteasome non-ATPase regulatory subunit 2 protein 20130415 {GO:0005515=IPI, GO:0002474=TAS, GO:0010467=TAS, GO:0044281=TAS, GO:0031145=TAS, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0000082=TAS, GO:0000087=TAS, GO:0016032=TAS, GO:0030234=IEA, GO:0006977=TAS, GO:0000209=TAS, GO:0000502=TAS, GO:0005838=TAS, GO:0042176=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0000075=TAS, GO:0002479=TAS, GO:0005654=TAS, GO:0022624=ISS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of protein catabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, viral reproduction cytosol, nucleoplasm, proteasome accessory complex, proteasome complex, proteasome regulatory particle enzyme regulator activity, protein binding Human UniProtKB:P62191 PSMD3 Reactome UniProtKB {GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0000082=Reactome:REACT_1783, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0030234=GO_REF:0000002, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0000502=PMID:8811196, GO:0042176=GO_REF:0000002, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0002479=Reactome:REACT_111178, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9034, GO:0022624=GO_REF:0000024, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} O43242 26S proteasome non-ATPase regulatory subunit 3 protein 20130213 {GO:0002474=TAS, GO:0010467=TAS, GO:0044281=TAS, GO:0031145=TAS, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0000082=TAS, GO:0000087=TAS, GO:0016032=TAS, GO:0030234=IEA, GO:0006977=TAS, GO:0000209=TAS, GO:0000502=TAS, GO:0042176=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0002479=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0022624=ISS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of protein catabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, viral reproduction cytosol, nucleoplasm, proteasome accessory complex, proteasome complex enzyme regulator activity Human PSMD4 InterPro UniProtKB {GO:0005515=PMID:17662948, GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0006511=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_13491, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0000082=Reactome:REACT_1783, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0000502=PMID:8811196, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0042590=Reactome:REACT_111119, GO:0051437=Reactome:REACT_6821, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0008540=GO_REF:0000002, GO:0002479=Reactome:REACT_111178, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9034, GO:0022624=GO_REF:0000024, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} Q5VWC4 26S proteasome non-ATPase regulatory subunit 4 protein 20130413 {GO:0005515=IPI, GO:0002474=TAS, GO:0010467=TAS, GO:0006511=IEA, GO:0044281=TAS, GO:0031145=TAS, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0000082=TAS, GO:0000087=TAS, GO:0016032=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0000502=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0042590=TAS, GO:0051437=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0008540=IEA, GO:0002479=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0022624=ISS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, ubiquitin-dependent protein catabolic process, viral reproduction cytosol, nucleoplasm, proteasome accessory complex, proteasome complex, proteasome regulatory particle, base subcomplex protein binding Human InterPro:IPR027040 PSMD5 InterPro UniProtKB {GO:0005515=PMID:19490896, GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0000082=Reactome:REACT_1783, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0000502=PMID:8811196, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0044183=GO_REF:0000002, GO:0008540=PMID:19490896, GO:0000075=Reactome:REACT_1538, GO:0002479=Reactome:REACT_111178, GO:0022624=GO_REF:0000024, GO:0005654=Reactome:REACT_9034, GO:0070682=PMID:19490896, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} Q4VXH0 26S proteasome non-ATPase regulatory subunit 5 protein 20130413 {GO:0005515=IPI, GO:0002474=TAS, GO:0010467=TAS, GO:0044281=TAS, GO:0031145=TAS, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0000082=TAS, GO:0000087=TAS, GO:0016032=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0000502=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0044183=IEA, GO:0008540=IDA, GO:0000075=TAS, GO:0002479=TAS, GO:0022624=ISS, GO:0005654=TAS, GO:0070682=TAS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, proteasome regulatory particle assembly, protein polyubiquitination, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, viral reproduction cytosol, nucleoplasm, proteasome accessory complex, proteasome complex, proteasome regulatory particle, base subcomplex protein binding, protein binding involved in protein folding Human InterPro:IPR019538 PSMD6 UniProtKB UniProtKB {GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0006200=PMID:10723133, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0000082=Reactome:REACT_1783, GO:0000087=Reactome:REACT_910, GO:0006508=PMID:10723133, GO:0016032=Reactome:REACT_6185, GO:0016887=PMID:10723133, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0000502=GO_REF:0000038, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0002479=Reactome:REACT_111178, GO:0000075=Reactome:REACT_1538, GO:0022624=GO_REF:0000024, GO:0005654=Reactome:REACT_9034, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} Q6UV22 26S proteasome non-ATPase regulatory subunit 6 protein 20130413 {GO:0002474=TAS, GO:0010467=TAS, GO:0006200=NAS, GO:0044281=TAS, GO:0031145=TAS, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0000082=TAS, GO:0000087=TAS, GO:0006508=NAS, GO:0016032=TAS, GO:0016887=NAS, GO:0006977=TAS, GO:0000209=TAS, GO:0000502=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0002479=TAS, GO:0000075=TAS, GO:0022624=ISS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS} ATP catabolic process, DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, proteolysis, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, viral reproduction cytosol, nucleoplasm, proteasome accessory complex, proteasome complex ATPase activity Human UniProtKB-KW:KW-0647 PSMD7 Reactome UniProtKB {GO:0005515=PMID:22078707, GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0000082=Reactome:REACT_1783, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0000502=PMID:8811196, GO:0005838=PMID:7755639, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0002479=Reactome:REACT_111178, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9034, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} P51665 26S proteasome non-ATPase regulatory subunit 7 protein 20130213 {GO:0005515=IPI, GO:0002474=TAS, GO:0010467=TAS, GO:0044281=TAS, GO:0031145=TAS, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0000082=TAS, GO:0000087=TAS, GO:0016032=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0000502=TAS, GO:0005838=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0002479=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, viral reproduction cytosol, nucleoplasm, proteasome complex, proteasome regulatory particle protein binding Human PSMD8 HPA UniProtKB {GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000052, GO:0000082=Reactome:REACT_1783, GO:0000087=Reactome:REACT_910, GO:0006508=GO_REF:0000002, GO:0016032=Reactome:REACT_6185, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0000502=PMID:8811196, GO:0005838=GO_REF:0000002, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0005730=GO_REF:0000052, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0002479=Reactome:REACT_111178, GO:0000075=Reactome:REACT_1538, GO:0022624=GO_REF:0000024, GO:0005654=Reactome:REACT_9034, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} P48556 26S proteasome non-ATPase regulatory subunit 8 protein 20080205 {GO:0002474=TAS, GO:0010467=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0031145=TAS, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0005737=IDA, GO:0000082=TAS, GO:0000087=TAS, GO:0006508=IEA, GO:0016032=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0000502=TAS, GO:0005838=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0005730=IDA, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0002479=TAS, GO:0000075=TAS, GO:0022624=ISS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, proteolysis, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, viral reproduction cytoplasm, cytosol, nucleolus, nucleoplasm, nucleus, proteasome accessory complex, proteasome complex, proteasome regulatory particle Human PSMD9 BHF-UCL UniProtKB {GO:0005515=PMID:19490896, GO:0002474=Reactome:REACT_75820, GO:0006511=PMID:9653651, GO:0010467=Reactome:REACT_71, GO:0005634=PMID:10567574, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0000082=Reactome:REACT_1783, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0032024=PMID:10567574, GO:0046676=PMID:16099819, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0005838=PMID:9653651, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0003713=PMID:10567574, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0043425=PMID:10567574, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0008540=PMID:19490896, GO:0002479=Reactome:REACT_111178, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9034, GO:0070682=PMID:19490896, GO:0045893=PMID:16293776, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} O00233 26S proteasome non-ATPase regulatory subunit 9 protein 20080328 {GO:0005515=IPI, GO:0002474=TAS, GO:0006511=NAS, GO:0010467=TAS, GO:0005634=ISS, GO:0044281=TAS, GO:0031145=TAS, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0000082=TAS, GO:0000087=TAS, GO:0016032=TAS, GO:0032024=ISS, GO:0046676=ISS, GO:0006977=TAS, GO:0000209=TAS, GO:0005838=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0003713=ISS, GO:0051437=TAS, GO:0042590=TAS, GO:0043425=ISS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0008540=IDA, GO:0002479=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0070682=IMP, GO:0045893=ISS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of insulin secretion, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of insulin secretion, positive regulation of transcription, DNA-dependent, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, proteasome regulatory particle assembly, protein polyubiquitination, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, ubiquitin-dependent protein catabolic process, viral reproduction cytosol, nucleoplasm, nucleus, proteasome regulatory particle, proteasome regulatory particle, base subcomplex bHLH transcription factor binding, protein binding, transcription coactivator activity Human UniProtKB:Q9WTV5 PSME1 Reactome UniProtKB {GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0000082=Reactome:REACT_1783, GO:0005737=PMID:16130169, GO:0008537=GO_REF:0000002, GO:0000087=Reactome:REACT_910, GO:0019884=GO_REF:0000019, GO:0016032=Reactome:REACT_6185, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0000502=PMID:8811196, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0061133=GO_REF:0000019, GO:0000075=Reactome:REACT_1538, GO:0002479=Reactome:REACT_111178, GO:0005654=Reactome:REACT_9034, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} Q06323 Proteasome activator complex subunit 1 protein 20130213 {GO:0002474=TAS, GO:0010467=TAS, GO:0044281=TAS, GO:0031145=TAS, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0000082=TAS, GO:0005737=TAS, GO:0008537=IEA, GO:0000087=TAS, GO:0019884=IEA, GO:0016032=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0000502=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0061133=IEA, GO:0000075=TAS, GO:0002479=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous antigen, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, viral reproduction cytoplasm, cytosol, nucleoplasm, proteasome activator complex, proteasome complex endopeptidase activator activity Human PSME2 Reactome UniProtKB {GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0000082=Reactome:REACT_1783, GO:0008537=GO_REF:0000002, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0000502=PMID:8811196, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0002479=Reactome:REACT_111178, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9034, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} Q9UL46 Proteasome activator complex subunit 2 protein 20130213 {GO:0002474=TAS, GO:0010467=TAS, GO:0044281=TAS, GO:0031145=TAS, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0000082=TAS, GO:0008537=IEA, GO:0000087=TAS, GO:0016032=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0000502=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0002479=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, viral reproduction cytosol, nucleoplasm, proteasome activator complex, proteasome complex Human PSME3 GOC UniProtKB {GO:0005515=PMID:22190034, GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0002039=PMID:18309296, GO:0000082=Reactome:REACT_1783, GO:0097371=PMID:18309296, GO:0008537=GO_REF:0000002, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0000502=PMID:8811196, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0061136=PMID:18309296, GO:0061133=PMID:18309296, GO:0010950=PMID:18309296, GO:0000075=Reactome:REACT_1538, GO:0002479=Reactome:REACT_111178, GO:0005654=Reactome:REACT_9034, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} P61289 Proteasome activator complex subunit 3 protein 20130413 {GO:0005515=IPI, GO:0002474=TAS, GO:0010467=TAS, GO:0044281=TAS, GO:0031145=TAS, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0002039=IDA, GO:0000082=TAS, GO:0097371=IDA, GO:0008537=IEA, GO:0000087=TAS, GO:0016032=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0000502=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0061136=IDA, GO:0061133=IDA, GO:0010950=IDA, GO:0000075=TAS, GO:0002479=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of endopeptidase activity, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of proteasomal protein catabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, viral reproduction cytosol, nucleoplasm, proteasome activator complex, proteasome complex MDM2/MDM4 family protein binding, endopeptidase activator activity, p53 binding, protein binding Human PSME4 Reactome UniProtKB {GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0044281=Reactome:REACT_111217, GO:0007283=GO_REF:0000037, GO:0031145=Reactome:REACT_6871, GO:0030154=GO_REF:0000037, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0000502=GO_REF:0000037, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0007275=GO_REF:0000037, GO:0042981=Reactome:REACT_13648, GO:0051439=Reactome:REACT_6837, GO:0016607=GO_REF:0000039, GO:0002479=Reactome:REACT_111178, GO:0000075=Reactome:REACT_1538, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} Q14997 Proteasome activator complex subunit 4 protein 20100909 {GO:0002474=TAS, GO:0010467=TAS, GO:0044281=TAS, GO:0007283=IEA, GO:0031145=TAS, GO:0030154=IEA, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0000087=TAS, GO:0016032=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0000502=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0007275=IEA, GO:0042981=TAS, GO:0051439=TAS, GO:0016607=IEA, GO:0002479=TAS, GO:0000075=TAS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cell differentiation, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, multicellular organismal development, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, spermatogenesis, viral reproduction cytosol, nuclear speck, proteasome complex Human PSMF1 GOC UniProtKB {GO:0005515=PMID:16713569, GO:0002474=Reactome:REACT_75820, GO:0006511=PMID:10764772, GO:0010467=Reactome:REACT_71, GO:0004866=PMID:10764772, GO:0044281=Reactome:REACT_111217, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_118617, GO:0000084=Reactome:REACT_899, GO:0034641=Reactome:REACT_13, GO:0000082=Reactome:REACT_1783, GO:0005737=GO_REF:0000052, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6185, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0005839=PMID:10764772, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006521=Reactome:REACT_13565, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0051439=Reactome:REACT_6837, GO:0010951=PMID:10764772, GO:0002479=Reactome:REACT_111178, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9034, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} Q92530 Proteasome inhibitor PI31 subunit protein 20130413 {GO:0005515=IPI, GO:0002474=TAS, GO:0006511=NAS, GO:0010467=TAS, GO:0004866=NAS, GO:0044281=TAS, GO:0031145=TAS, GO:0005829=TAS, GO:0000084=TAS, GO:0034641=TAS, GO:0000082=TAS, GO:0005737=IDA, GO:0000087=TAS, GO:0016032=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0005839=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0006521=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0051439=TAS, GO:0010951=NAS, GO:0002479=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G1/S transition of mitotic cell cycle, M phase of mitotic cell cycle, RNA metabolic process, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, cell cycle checkpoint, cellular nitrogen compound metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of endopeptidase activity, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, regulation of apoptotic process, regulation of cellular amino acid metabolic process, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, small molecule metabolic process, ubiquitin-dependent protein catabolic process, viral reproduction cytoplasm, cytosol, nucleoplasm, proteasome core complex endopeptidase inhibitor activity, protein binding Human PSMG1 UniProtKB UniProtKB {GO:0043248=PMID:16251969, GO:0005515=PMID:16251969, GO:0005737=PMID:15670775, GO:0005783=PMID:15590417} O95456 Proteasome assembly chaperone 1 protein 20080129 {GO:0043248=IDA, GO:0005515=IPI, GO:0005737=IDA, GO:0005783=IDA} proteasome assembly cytoplasm, endoplasmic reticulum protein binding Human UniProtKB:P28066 PSMG2 UniProtKB UniProtKB {GO:0005515=PMID:16251969, GO:0043248=PMID:16251969, GO:0007094=GO_REF:0000019, GO:0006915=GO_REF:0000019, GO:0005634=GO_REF:0000024, GO:0042981=GO_REF:0000019} Q969U7 Proteasome assembly chaperone 2 protein 20080129 {GO:0005515=IPI, GO:0043248=IDA, GO:0007094=IEA, GO:0006915=IEA, GO:0005634=ISS, GO:0042981=IEA} apoptotic process, mitotic spindle assembly checkpoint, proteasome assembly, regulation of apoptotic process nucleus protein binding Human UniProtKB:Q9EST4 PSMG3 null null {} null null null null {} null null null PSMG4 null null {} null null null null {} null null null PSORS1C2 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005576=GO_REF:0000039, GO:0005575=GO_REF:0000015} Q9UIG4 Psoriasis susceptibility 1 candidate gene 2 protein protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0005576=IEA, GO:0005575=ND} biological_process cellular_component, extracellular region molecular_function Human PSPC1 HPA UniProtKB {GO:0005737=GO_REF:0000039, GO:0006355=GO_REF:0000037, GO:0042382=GO_REF:0000019, GO:0016607=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0016363=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q8WXF1 Paraspeckle component 1 protein 20110516 {GO:0005737=IEA, GO:0006355=IEA, GO:0042382=IEA, GO:0016607=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0016363=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nuclear matrix, nuclear speck, nucleolus, nucleus, paraspeckles RNA binding, nucleotide binding NOT Human PSPH Reactome UniProtKB {GO:0043005=GO_REF:0000019, GO:0000287=PMID:15291819, GO:0005509=PMID:12777757, GO:0008652=Reactome:REACT_238, GO:0044281=Reactome:REACT_111217, GO:0033574=GO_REF:0000019, GO:0004647=Reactome:REACT_115834, GO:0042803=PMID:12777757, GO:0009612=GO_REF:0000019, GO:0005829=Reactome:REACT_115834, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000033, GO:0031667=GO_REF:0000019, GO:0006564=Reactome:REACT_115789, GO:0006563=PMID:15291819} P78330 Phosphoserine phosphatase protein 20101018 {GO:0043005=IEA, GO:0000287=IDA, GO:0005509=IDA, GO:0008652=TAS, GO:0044281=TAS, GO:0033574=IEA, GO:0004647=TAS, GO:0042803=IPI, GO:0009612=IEA, GO:0005829=TAS, GO:0034641=TAS, GO:0005737=IBA, GO:0031667=IEA, GO:0006564=TAS, GO:0006563=IDA} L-serine biosynthetic process, L-serine metabolic process, cellular amino acid biosynthetic process, cellular nitrogen compound metabolic process, response to mechanical stimulus, response to nutrient levels, response to testosterone stimulus, small molecule metabolic process cytoplasm, cytosol, neuron projection calcium ion binding, magnesium ion binding, phosphoserine phosphatase activity, protein homodimerization activity Human PSPN Reactome UniProtKB {GO:0001658=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0005102=PMID:9491986, GO:0007417=PMID:9491986, GO:0005615=GO_REF:0000019, GO:0008083=GO_REF:0000037, GO:0007399=PMID:9491986} O60542 Persephin protein 20130301 {GO:0001658=IEA, GO:0007411=TAS, GO:0005102=TAS, GO:0007417=TAS, GO:0005615=IEA, GO:0008083=IEA, GO:0007399=TAS} axon guidance, branching involved in ureteric bud morphogenesis, central nervous system development, nervous system development extracellular space growth factor activity, receptor binding Human PSRC1 BHF-UCL UniProtKB {GO:0008017=PMID:12427559, GO:0005515=PMID:18411309, GO:0030308=PMID:12427559, GO:0031116=PMID:12427559, GO:0060236=PMID:18411309, GO:0001578=PMID:12427559, GO:0005819=PMID:12427559, GO:0030496=PMID:12427559, GO:0005829=PMID:18411309, GO:0005737=PMID:12427559, GO:0007049=PMID:12427559, GO:0000922=PMID:18411309, GO:0015630=PMID:12427559, GO:0005876=PMID:18411309, GO:0007080=PMID:18411309, GO:0045893=PMID:12427559, GO:0051301=GO_REF:0000037} Q6PGN9 Proline/serine-rich coiled-coil protein 1 protein 20080131 {GO:0008017=ISS, GO:0005515=IPI, GO:0030308=ISS, GO:0031116=ISS, GO:0060236=IDA, GO:0001578=ISS, GO:0005819=ISS, GO:0030496=ISS, GO:0005829=IDA, GO:0005737=ISS, GO:0007049=ISS, GO:0000922=IDA, GO:0015630=ISS, GO:0005876=IDA, GO:0007080=IDA, GO:0045893=ISS, GO:0051301=IEA} cell cycle, cell division, microtubule bundle formation, mitotic metaphase plate congression, negative regulation of cell growth, positive regulation of microtubule polymerization, positive regulation of transcription, DNA-dependent, regulation of mitotic spindle organization cytoplasm, cytosol, microtubule cytoskeleton, midbody, spindle, spindle microtubule, spindle pole microtubule binding, protein binding Human UniProtKB:Q9D0P7 PSTK UniPathway UniProtKB {GO:0005739=GO_REF:0000019, GO:0000049=GO_REF:0000019, GO:0016301=GO_REF:0000019, GO:0001514=GO_REF:0000019, GO:0097056=GO_REF:0000041, GO:0005524=GO_REF:0000037} Q8IV42 L-seryl-tRNA(Sec) kinase protein 20130413 {GO:0005739=IEA, GO:0000049=IEA, GO:0016301=IEA, GO:0001514=IEA, GO:0097056=IEA, GO:0005524=IEA} selenocysteine incorporation, selenocysteinyl-tRNA(Sec) biosynthetic process mitochondrion ATP binding, kinase activity, tRNA binding Human UniPathway:UPA00906 PSTPIP1 Reactome UniProtKB {GO:0001725=GO_REF:0000019, GO:0005826=GO_REF:0000019, GO:0048471=GO_REF:0000039, GO:0019903=GO_REF:0000019, GO:0003779=GO_REF:0000019, GO:0032154=GO_REF:0000039, GO:0030027=GO_REF:0000039, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_75934, GO:0007165=PMID:9857189, GO:0045087=Reactome:REACT_6802, GO:0016491=GO_REF:0000002, GO:0007155=GO_REF:0000037} O43586 Proline-serine-threonine phosphatase-interacting protein 1 protein 20100615 {GO:0001725=IEA, GO:0005826=IEA, GO:0048471=IEA, GO:0019903=IEA, GO:0003779=IEA, GO:0032154=IEA, GO:0030027=IEA, GO:0035872=TAS, GO:0005829=TAS, GO:0007165=TAS, GO:0045087=TAS, GO:0016491=IEA, GO:0007155=IEA} cell adhesion, innate immune response, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, signal transduction actomyosin contractile ring, cleavage furrow, cytosol, lamellipodium, perinuclear region of cytoplasm, stress fiber actin binding, oxidoreductase activity, protein phosphatase binding Human PSTPIP2 UniProtKB UniProtKB {GO:0016020=GO_REF:0000039, GO:0005856=GO_REF:0000019, GO:0005829=GO_REF:0000019} Q9H939 Proline-serine-threonine phosphatase-interacting protein 2 protein 20130413 {GO:0016020=IEA, GO:0005856=IEA, GO:0005829=IEA} cytoskeleton, cytosol, membrane Human UniProtKB-SubCell:SL-0162 PTAFR HPA UniProtKB {GO:0005886=GO_REF:0000052, GO:0004930=PMID:1322356, GO:0048015=PMID:1657923, GO:0019221=Reactome:REACT_25229, GO:0005730=GO_REF:0000052, GO:0001875=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0001816=GO_REF:0000019, GO:0043231=GO_REF:0000052, GO:0001530=GO_REF:0000019, GO:0006955=PMID:8892648, GO:0032959=GO_REF:0000019, GO:0006954=GO_REF:0000019, GO:0005543=PMID:1657923, GO:0004992=PMID:1657923, GO:0007186=PMID:1657923, GO:0006935=GO_REF:0000037, GO:0016020=PMID:1374385, GO:0005887=PMID:8168510, GO:0016021=PMID:1281995, GO:0060333=Reactome:REACT_25078} P25105 Platelet-activating factor receptor protein 20101115 {GO:0005886=IDA, GO:0004930=TAS, GO:0048015=IDA, GO:0019221=TAS, GO:0005730=IDA, GO:0001875=IEA, GO:0005634=IDA, GO:0001816=IEA, GO:0043231=IDA, GO:0001530=IEA, GO:0006955=TAS, GO:0032959=IEA, GO:0006954=IEA, GO:0005543=IDA, GO:0004992=IDA, GO:0007186=IMP, GO:0006935=IEA, GO:0016020=IDA, GO:0005887=TAS, GO:0016021=NAS, GO:0060333=TAS} G-protein coupled receptor signaling pathway, chemotaxis, cytokine production, cytokine-mediated signaling pathway, immune response, inflammatory response, inositol trisphosphate biosynthetic process, interferon-gamma-mediated signaling pathway, phosphatidylinositol-mediated signaling integral to membrane, integral to plasma membrane, intracellular membrane-bounded organelle, membrane, nucleolus, nucleus, plasma membrane G-protein coupled receptor activity, lipopolysaccharide binding, lipopolysaccharide receptor activity, phospholipid binding, platelet activating factor receptor activity Human PTAR1 InterPro UniProtKB {GO:0018342=GO_REF:0000002, GO:0008318=GO_REF:0000002} Q7Z6K3 Protein prenyltransferase alpha subunit repeat-containing protein 1 protein 20130413 {GO:0018342=IEA, GO:0008318=IEA} protein prenylation protein prenyltransferase activity Human InterPro:IPR002088 PTBP1 IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0008380=Reactome:REACT_1735, GO:0006397=PMID:1906036, GO:0010467=Reactome:REACT_71, GO:0048025=PMID:15009664, GO:0003723=PMID:1906036, GO:0005730=PMID:1641332, GO:0005634=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0008187=PMID:1906036, GO:0000166=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0033119=PMID:18335065, GO:0000381=PMID:21518792, GO:0005654=Reactome:REACT_1935, GO:0051148=PMID:21518792, GO:0036002=PMID:16260624} P26599 Polypyrimidine tract-binding protein 1 protein 20130415 {GO:0005515=IPI, GO:0008380=TAS, GO:0006397=TAS, GO:0010467=TAS, GO:0048025=IDA, GO:0003723=TAS, GO:0005730=TAS, GO:0005634=IEA, GO:0003676=IEA, GO:0008187=TAS, GO:0000166=IEA, GO:0000398=TAS, GO:0033119=IDA, GO:0000381=IDA, GO:0005654=TAS, GO:0051148=IDA, GO:0036002=IDA} RNA splicing, gene expression, mRNA processing, mRNA splicing, via spliceosome, negative regulation of RNA splicing, negative regulation of mRNA splicing, via spliceosome, negative regulation of muscle cell differentiation, regulation of alternative mRNA splicing, via spliceosome nucleolus, nucleoplasm, nucleus RNA binding, nucleic acid binding, nucleotide binding, poly-pyrimidine tract binding, pre-mRNA binding, protein binding Human UniProtKB:Q96PU8 PTBP2 UniProtKB UniProtKB {GO:2000177=GO_REF:0000019, GO:0006397=GO_REF:0000002, GO:0000166=GO_REF:0000002, GO:0033119=PMID:18335065, GO:0003723=GO_REF:0000002, GO:0006376=GO_REF:0000019, GO:0005681=GO_REF:0000019, GO:0005634=GO_REF:0000002, GO:0003729=GO_REF:0000019} Q9UKA9 Polypyrimidine tract-binding protein 2 protein 20111208 {GO:2000177=IEA, GO:0006397=IEA, GO:0000166=IEA, GO:0033119=IDA, GO:0003723=IEA, GO:0006376=IEA, GO:0005681=IEA, GO:0005634=IEA, GO:0003729=IEA} mRNA processing, mRNA splice site selection, negative regulation of RNA splicing, regulation of neural precursor cell proliferation nucleus, spliceosomal complex RNA binding, mRNA binding, nucleotide binding Human PTBP3 PINC UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0043249=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0033119=PMID:18335065, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000002, GO:0045595=GO_REF:0000019, GO:0009653=PMID:10207106} O95758 Polypyrimidine tract-binding protein 3 protein 20031119 {GO:0008380=IEA, GO:0006397=IEA, GO:0043249=IEA, GO:0000166=IEA, GO:0033119=IDA, GO:0003723=IEA, GO:0005634=IEA, GO:0045595=IEA, GO:0009653=TAS} RNA splicing, anatomical structure morphogenesis, erythrocyte maturation, mRNA processing, negative regulation of RNA splicing, regulation of cell differentiation nucleus RNA binding, nucleotide binding Human PTCD1 UniProtKB UniProtKB {GO:0005739=PMID:19651879, GO:0000049=PMID:19651879, GO:0005759=GO_REF:0000024, GO:0042780=PMID:21857155} O75127 Pentatricopeptide repeat-containing protein 1, mitochondrial protein 20120921 {GO:0005739=IDA, GO:0000049=IDA, GO:0005759=ISS, GO:0042780=IDA} tRNA 3'-end processing mitochondrial matrix, mitochondrion tRNA binding Human UniProtKB:A2VD13 PTCD2 UniProtKB UniProtKB {GO:0006397=GO_REF:0000037, GO:0048747=GO_REF:0000019, GO:0005739=PMID:18729827, GO:0001889=GO_REF:0000019, GO:0055010=GO_REF:0000019, GO:0001822=GO_REF:0000019, GO:0007005=GO_REF:0000019, GO:0050684=GO_REF:0000024} Q8WV60 Pentatricopeptide repeat-containing protein 2, mitochondrial protein 20120914 {GO:0006397=IEA, GO:0048747=IEA, GO:0005739=IDA, GO:0001889=IEA, GO:0055010=IEA, GO:0001822=IEA, GO:0007005=IEA, GO:0050684=ISS} kidney development, liver development, mRNA processing, mitochondrion organization, muscle fiber development, regulation of mRNA processing, ventricular cardiac muscle tissue morphogenesis mitochondrion Human PTCD3 UniProtKB UniProtKB {GO:0005739=PMID:19427859, GO:0032543=PMID:19427859, GO:0043024=PMID:19427859, GO:0019843=PMID:19427859, GO:0006417=GO_REF:0000037} Q96EY7 Pentatricopeptide repeat domain-containing protein 3, mitochondrial protein 20120914 {GO:0005739=IDA, GO:0032543=IMP, GO:0043024=IDA, GO:0019843=IDA, GO:0006417=IEA} mitochondrial translation, regulation of translation mitochondrion rRNA binding, ribosomal small subunit binding Human PTCH1 BHF-UCL UniProtKB {GO:0035137=GO_REF:0000019, GO:0005515=PMID:11278759, GO:0001658=GO_REF:0000019, GO:0050680=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0005113=PMID:22228099, GO:0007224=PMID:17850284, GO:0043231=PMID:11278759, GO:0061005=GO_REF:0000019, GO:0060644=GO_REF:0000019, GO:0071397=PMID:11278759, GO:0016485=GO_REF:0000024, GO:0009887=GO_REF:0000024, GO:0051782=GO_REF:0000019, GO:0060603=GO_REF:0000019, GO:0005794=PMID:11278759, GO:0030332=PMID:11331587, GO:0030496=GO_REF:0000019, GO:0001843=GO_REF:0000019, GO:0000122=PMID:16229683, GO:0072203=GO_REF:0000019, GO:0060037=PMID:8981943, GO:0061053=PMID:8681379, GO:0005119=PMID:9811851, GO:0008544=GO_REF:0000019, GO:0007420=GO_REF:0000024, GO:0072001=PMID:17850284, GO:0048471=PMID:11278759, GO:0005886=PMID:12635140, GO:0021532=PMID:8681379, GO:0045879=PMID:11001584, GO:0030326=GO_REF:0000024, GO:0009953=GO_REF:0000024, GO:0010875=PMID:21931618, GO:0032880=GO_REF:0000019, GO:0040015=GO_REF:0000024, GO:0015485=PMID:21931618, GO:0010157=GO_REF:0000019, GO:0021904=GO_REF:0000019, GO:0008201=GO_REF:0000019, GO:0035108=PMID:8681379, GO:0021997=GO_REF:0000024, GO:0042593=GO_REF:0000019, GO:0043616=GO_REF:0000019, GO:0007346=GO_REF:0000019, GO:0003007=GO_REF:0000019, GO:0008589=GO_REF:0000024, GO:0005901=PMID:11278759, GO:0008158=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0097108=PMID:9811851} Q13635 Protein patched homolog 1 protein 20111120 {GO:0035137=IEA, GO:0005515=IPI, GO:0001658=IEA, GO:0050680=IEA, GO:0032403=IEA, GO:0005113=IPI, GO:0007224=IEP, GO:0043231=IDA, GO:0061005=IEA, GO:0060644=IEA, GO:0071397=IMP, GO:0016485=ISS, GO:0009887=ISS, GO:0051782=IEA, GO:0060603=IEA, GO:0005794=IDA, GO:0030332=IPI, GO:0030496=IEA, GO:0001843=IEA, GO:0000122=IMP, GO:0072203=IEA, GO:0060037=IMP, GO:0061053=IMP, GO:0005119=IPI, GO:0008544=IEA, GO:0007420=ISS, GO:0072001=IEP, GO:0048471=IDA, GO:0005886=IDA, GO:0021532=IMP, GO:0045879=TAS, GO:0030326=ISS, GO:0009953=ISS, GO:0010875=IDA, GO:0032880=IEA, GO:0040015=ISS, GO:0015485=IDA, GO:0010157=IEA, GO:0021904=IEA, GO:0008201=IEA, GO:0035108=IMP, GO:0021997=ISS, GO:0042593=IEA, GO:0043616=IEA, GO:0007346=IEA, GO:0003007=IEA, GO:0008589=ISS, GO:0005901=IDA, GO:0008158=IEA, GO:0016021=IEA, GO:0097108=IPI} brain development, branching involved in ureteric bud morphogenesis, cell differentiation involved in kidney development, cell proliferation involved in metanephros development, cellular response to cholesterol, dorsal/ventral neural tube patterning, dorsal/ventral pattern formation, embryonic limb morphogenesis, epidermis development, glucose homeostasis, heart morphogenesis, hindlimb morphogenesis, keratinocyte proliferation, limb morphogenesis, mammary gland duct morphogenesis, mammary gland epithelial cell differentiation, negative regulation of cell division, negative regulation of epithelial cell proliferation, negative regulation of multicellular organism growth, negative regulation of smoothened signaling pathway, negative regulation of transcription from RNA polymerase II promoter, neural plate axis specification, neural tube closure, neural tube patterning, organ morphogenesis, pharyngeal system development, positive regulation of cholesterol efflux, protein processing, regulation of mitotic cell cycle, regulation of protein localization, regulation of smoothened signaling pathway, renal system development, response to chlorate, smoothened signaling pathway, somite development Golgi apparatus, caveola, integral to membrane, intracellular membrane-bounded organelle, midbody, perinuclear region of cytoplasm, plasma membrane cholesterol binding, cyclin binding, hedgehog family protein binding, hedgehog receptor activity, heparin binding, patched binding, protein binding, protein complex binding, smoothened binding Human PTCH2 BHF-UCL UniProtKB {GO:0005119=PMID:9811851, GO:0042633=GO_REF:0000019, GO:0008158=PMID:11001584, GO:0045879=PMID:11001584, GO:0043588=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0097108=PMID:9811851} Q9Y6C5 Protein patched homolog 2 protein 20111117 {GO:0005119=IPI, GO:0042633=IEA, GO:0008158=TAS, GO:0045879=TAS, GO:0043588=IEA, GO:0016021=IEA, GO:0097108=IPI} hair cycle, negative regulation of smoothened signaling pathway, skin development integral to membrane hedgehog family protein binding, hedgehog receptor activity, smoothened binding Human UniProtKB:Q99835 PTCHD2 UniProtKB UniProtKB {GO:0042632=PMID:19179482, GO:0003674=GO_REF:0000015, GO:0031965=PMID:19179482, GO:0005783=PMID:19179482, GO:0032368=PMID:15645143, GO:0008158=GO_REF:0000002, GO:0016021=PMID:15645143, GO:0007224=PMID:16258256} Q9P2K9 Patched domain-containing protein 2 protein 20110107 {GO:0042632=ISS, GO:0003674=ND, GO:0031965=ISS, GO:0005783=ISS, GO:0032368=NAS, GO:0008158=IEA, GO:0016021=NAS, GO:0007224=NAS} cholesterol homeostasis, regulation of lipid transport, smoothened signaling pathway endoplasmic reticulum, integral to membrane, nuclear membrane hedgehog receptor activity, molecular_function Human PTCHD3 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0007286=PMID:17904097, GO:0008158=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} Q3KNS1 Patched domain-containing protein 3 protein 20110107 {GO:0003674=ND, GO:0007286=NAS, GO:0008158=IEA, GO:0005575=ND, GO:0016021=IEA} spermatid development cellular_component, integral to membrane hedgehog receptor activity, molecular_function Human PTCRA UniProtKB UniProtKB {GO:0005515=PMID:22795130, GO:0070244=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q6ISU1 Pre T-cell antigen receptor alpha protein 20120723 {GO:0005515=IPI, GO:0070244=IEA, GO:0016021=IEA} negative regulation of thymocyte apoptotic process integral to membrane protein binding Human UniProtKB:Q8BHC7 PTDSS1 ENSEMBL UniProtKB {GO:0016020=GO_REF:0000024, GO:0005789=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0016740=GO_REF:0000037, GO:0006659=GO_REF:0000002, GO:0046474=Reactome:REACT_121401} Q9BUQ5 Phosphatidylserine synthase 1 protein 20130413 {GO:0016020=ISS, GO:0005789=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0006644=TAS, GO:0016740=IEA, GO:0006659=IEA, GO:0046474=TAS} glycerophospholipid biosynthetic process, phosphatidylserine biosynthetic process, phospholipid metabolic process, small molecule metabolic process endoplasmic reticulum membrane, integral to membrane, membrane transferase activity Human Ensembl:ENSMUSP00000021990 PTDSS2 Reactome UniProtKB {GO:0016020=GO_REF:0000024, GO:0005789=Reactome:REACT_121084, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0006659=Reactome:REACT_120823, GO:0003882=GO_REF:0000019, GO:0046474=Reactome:REACT_121401} Q9BVG9 Phosphatidylserine synthase 2 protein 20130301 {GO:0016020=ISS, GO:0005789=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0006644=TAS, GO:0006659=TAS, GO:0003882=IEA, GO:0046474=TAS} glycerophospholipid biosynthetic process, phosphatidylserine biosynthetic process, phospholipid metabolic process, small molecule metabolic process endoplasmic reticulum membrane, integral to membrane, membrane CDP-diacylglycerol-serine O-phosphatidyltransferase activity Human PTEN GOC UniProtKB {GO:0005515=PMID:19345329, GO:0010997=PMID:21241890, GO:0042995=PMID:10760291, GO:0007507=GO_REF:0000024, GO:0060997=GO_REF:0000024, GO:0061002=GO_REF:0000024, GO:0033032=GO_REF:0000019, GO:0021542=GO_REF:0000024, GO:0000287=GO_REF:0000002, GO:2000463=GO_REF:0000024, GO:0060134=GO_REF:0000024, GO:2000134=PMID:21241890, GO:0030165=PMID:10646847, GO:0007270=GO_REF:0000024, GO:0090394=GO_REF:0000024, GO:0045087=Reactome:REACT_6802, GO:0035176=GO_REF:0000024, GO:0008138=GO_REF:0000002, GO:0006644=Reactome:REACT_121175, GO:0043005=GO_REF:0000024, GO:0050852=Reactome:REACT_12526, GO:0045475=GO_REF:0000024, GO:0060736=GO_REF:0000019, GO:0007092=PMID:21241890, GO:0043647=Reactome:REACT_150312, GO:0090344=GO_REF:0000019, GO:0005634=PMID:21241890, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_150242, GO:0051091=PMID:20123964, GO:0032286=GO_REF:0000024, GO:0007626=GO_REF:0000024, GO:0060070=PMID:20123964, GO:0043220=GO_REF:0000024, GO:0042711=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0048015=Reactome:REACT_12464, GO:0048853=GO_REF:0000024, GO:0048854=GO_REF:0000024, GO:2000808=GO_REF:0000024, GO:0046855=PMID:9593664, GO:0004438=PMID:9811831, GO:0046856=PMID:21828076, GO:0051717=Reactome:REACT_150242, GO:0050680=GO_REF:0000019, GO:0060291=GO_REF:0000019, GO:0035335=PMID:9256433, GO:0035749=GO_REF:0000024, GO:0007173=Reactome:REACT_9417, GO:0007611=GO_REF:0000024, GO:0002902=GO_REF:0000019, GO:0030336=PMID:17880912, GO:0019901=GO_REF:0000019, GO:0033555=GO_REF:0000024, GO:0014067=PMID:18082964, GO:0007417=GO_REF:0000024, GO:0007416=GO_REF:0000024, GO:0060074=GO_REF:0000024, GO:0048738=GO_REF:0000019, GO:0045792=GO_REF:0000024, GO:0016314=Reactome:REACT_121053, GO:0043542=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0010975=GO_REF:0000024, GO:0043491=GO_REF:0000024, GO:0009898=PMID:10940933, GO:0050771=GO_REF:0000024, GO:0019899=PMID:16845383, GO:0060179=GO_REF:0000019, GO:0051898=PMID:10760291, GO:0008284=GO_REF:0000024, GO:0008285=PMID:19057511, GO:0032535=GO_REF:0000024, GO:0005886=PMID:10760291, GO:0008283=PMID:10918569, GO:0000079=PMID:10918569, GO:0051895=PMID:9616126, GO:0008289=GO_REF:0000037, GO:0005737=PMID:21241890, GO:0031647=PMID:10866658, GO:0006470=PMID:9367992, GO:0051800=Reactome:REACT_120852, GO:0004721=PMID:21241890, GO:0004722=PMID:9256433, GO:0060024=GO_REF:0000024, GO:0031642=GO_REF:0000019, GO:0004725=PMID:9256433, GO:0046621=GO_REF:0000024, GO:0090071=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0006661=Reactome:REACT_121025, GO:0021955=GO_REF:0000024, GO:0050821=PMID:20123964, GO:0006915=GO_REF:0000037, GO:0006917=GO_REF:0000024, GO:0001525=GO_REF:0000019, GO:0031658=PMID:21241890, GO:2000060=PMID:21241890, GO:0097105=GO_REF:0000024, GO:0016477=GO_REF:0000024, GO:0016605=GO_REF:0000039, GO:0001933=PMID:20123964, GO:0097107=GO_REF:0000024} P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN protein 20130413 {GO:0005515=IPI, GO:0010997=IPI, GO:0042995=IDA, GO:0007507=ISS, GO:0060997=ISS, GO:0061002=ISS, GO:0033032=IEA, GO:0021542=ISS, GO:0000287=IEA, GO:2000463=ISS, GO:0060134=ISS, GO:2000134=IDA, GO:0030165=IPI, GO:0007270=ISS, GO:0090394=ISS, GO:0045087=TAS, GO:0035176=ISS, GO:0008138=IEA, GO:0006644=TAS, GO:0043005=ISS, GO:0050852=TAS, GO:0045475=ISS, GO:0060736=IEA, GO:0007092=IDA, GO:0043647=TAS, GO:0090344=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0005829=TAS, GO:0051091=IMP, GO:0032286=ISS, GO:0007626=ISS, GO:0060070=IDA, GO:0043220=ISS, GO:0042711=IEA, GO:0048011=TAS, GO:0048015=TAS, GO:0048853=ISS, GO:0048854=ISS, GO:2000808=ISS, GO:0046855=IDA, GO:0004438=IDA, GO:0046856=IMP, GO:0051717=TAS, GO:0050680=IEA, GO:0060291=IEA, GO:0035335=IDA, GO:0035749=ISS, GO:0007173=TAS, GO:0007611=ISS, GO:0002902=IEA, GO:0030336=IMP, GO:0019901=IEA, GO:0033555=ISS, GO:0014067=TAS, GO:0007417=ISS, GO:0007416=ISS, GO:0060074=ISS, GO:0048738=IEA, GO:0045792=ISS, GO:0016314=TAS, GO:0043542=IEA, GO:0008543=TAS, GO:0010975=ISS, GO:0043491=ISS, GO:0009898=IDA, GO:0050771=ISS, GO:0019899=IPI, GO:0060179=IEA, GO:0051898=IMP, GO:0008284=ISS, GO:0008285=IDA, GO:0032535=ISS, GO:0005886=IDA, GO:0008283=TAS, GO:0000079=TAS, GO:0051895=IMP, GO:0008289=IEA, GO:0005737=IDA, GO:0031647=IMP, GO:0006470=TAS, GO:0051800=TAS, GO:0004721=IDA, GO:0004722=IDA, GO:0060024=ISS, GO:0031642=IEA, GO:0004725=IDA, GO:0046621=ISS, GO:0090071=IEA, GO:0043066=IEA, GO:0006661=TAS, GO:0021955=ISS, GO:0050821=IDA, GO:0006915=IEA, GO:0006917=ISS, GO:0001525=IEA, GO:0031658=IDA, GO:2000060=IDA, GO:0097105=ISS, GO:0016477=ISS, GO:0016605=IEA, GO:0001933=IDA, GO:0097107=ISS} T cell receptor signaling pathway, activation of mitotic anaphase-promoting complex activity, angiogenesis, apoptotic process, brain morphogenesis, canonical Wnt receptor signaling pathway, cardiac muscle tissue development, cell migration, cell proliferation, central nervous system development, central nervous system myelin maintenance, central nervous system neuron axonogenesis, dendritic spine morphogenesis, dentate gyrus development, endothelial cell migration, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, forebrain morphogenesis, heart development, induction of apoptosis, innate immune response, inositol phosphate dephosphorylation, inositol phosphate metabolic process, learning or memory, locomotor rhythm, locomotory behavior, long-term synaptic potentiation, male mating behavior, maternal behavior, multicellular organismal response to stress, negative regulation of G1/S transition of mitotic cell cycle, negative regulation of apoptotic process, negative regulation of axonogenesis, negative regulation of cell aging, negative regulation of cell migration, negative regulation of cell proliferation, negative regulation of cell size, negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S, negative regulation of dendritic spine morphogenesis, negative regulation of epithelial cell proliferation, negative regulation of excitatory postsynaptic membrane potential, negative regulation of focal adhesion assembly, negative regulation of myelination, negative regulation of organ growth, negative regulation of phosphatidylinositol 3-kinase cascade, negative regulation of protein kinase B signaling cascade, negative regulation of protein phosphorylation, negative regulation of ribosome biogenesis, negative regulation of synaptic vesicle clustering, neuron-neuron synaptic transmission, neurotrophin TRK receptor signaling pathway, peptidyl-tyrosine dephosphorylation, phosphatidylinositol biosynthetic process, phosphatidylinositol dephosphorylation, phosphatidylinositol-mediated signaling, phospholipid metabolic process, positive regulation of cell proliferation, positive regulation of excitatory postsynaptic membrane potential, positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process, positive regulation of sequence-specific DNA binding transcription factor activity, postsynaptic density assembly, prepulse inhibition, presynaptic membrane assembly, prostate gland growth, protein dephosphorylation, protein kinase B signaling cascade, protein stabilization, regulation of B cell apoptotic process, regulation of cellular component size, regulation of cyclin-dependent protein serine/threonine kinase activity, regulation of myeloid cell apoptotic process, regulation of neuron projection development, regulation of protein stability, rhythmic synaptic transmission, small molecule metabolic process, social behavior, synapse assembly, synapse maturation PML body, Schmidt-Lanterman incisure, cell projection, cytoplasm, cytosol, internal side of plasma membrane, myelin sheath adaxonal region, neuron projection, nucleus, plasma membrane PDZ domain binding, anaphase-promoting complex binding, enzyme binding, inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity, lipid binding, magnesium ion binding, phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity, phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity, phosphatidylinositol-3-phosphatase activity, phosphoprotein phosphatase activity, protein binding, protein kinase binding, protein serine/threonine phosphatase activity, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human PTER InterPro UniProtKB {GO:0016788=GO_REF:0000002, GO:0009056=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q96BW5 Phosphotriesterase-related protein protein 20130413 {GO:0016788=IEA, GO:0009056=IEA, GO:0008270=IEA} catabolic process hydrolase activity, acting on ester bonds, zinc ion binding Human InterPro:IPR017947 PTF1A Reactome UniProtKB {GO:0005667=GO_REF:0000024, GO:0006355=GO_REF:0000024, GO:0060042=GO_REF:0000019, GO:0005634=GO_REF:0000024, GO:0009790=GO_REF:0000019, GO:0048663=GO_REF:0000019, GO:0003677=GO_REF:0000024, GO:0043565=GO_REF:0000019, GO:0048384=GO_REF:0000019, GO:0001077=GO_REF:0000019, GO:0005737=GO_REF:0000024, GO:0031018=Reactome:REACT_13778, GO:0031017=GO_REF:0000024, GO:0046983=GO_REF:0000002, GO:0009888=PMID:12185368, GO:0030902=GO_REF:0000019} Q7RTS3 Pancreas transcription factor 1 subunit alpha protein 20130301 {GO:0005667=ISS, GO:0006355=ISS, GO:0060042=IEA, GO:0005634=ISS, GO:0009790=IEA, GO:0048663=IEA, GO:0003677=ISS, GO:0043565=IEA, GO:0048384=IEA, GO:0001077=IEA, GO:0005737=ISS, GO:0031018=TAS, GO:0031017=ISS, GO:0046983=IEA, GO:0009888=IDA, GO:0030902=IEA} embryo development, endocrine pancreas development, exocrine pancreas development, hindbrain development, neuron fate commitment, regulation of transcription, DNA-dependent, retina morphogenesis in camera-type eye, retinoic acid receptor signaling pathway, tissue development cytoplasm, nucleus, transcription factor complex DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, protein dimerization activity, sequence-specific DNA binding Human PTGDR BHF-UCL UniProtKB {GO:0005515=PMID:20959461, GO:0006954=GO_REF:0000019, GO:0005886=PMID:20959461, GO:0007186=PMID:7642548, GO:0030238=GO_REF:0000019, GO:0071799=GO_REF:0000019, GO:0046085=GO_REF:0000019, GO:0030431=GO_REF:0000019, GO:0001785=GO_REF:0000019, GO:0016021=PMID:7642548, GO:0004956=PMID:7642548} Q13258 Prostaglandin D2 receptor protein 20101028 {GO:0005515=IPI, GO:0006954=IEA, GO:0005886=IDA, GO:0007186=NAS, GO:0030238=IEA, GO:0071799=IEA, GO:0046085=IEA, GO:0030431=IEA, GO:0001785=IEA, GO:0016021=NAS, GO:0004956=NAS} G-protein coupled receptor signaling pathway, adenosine metabolic process, cellular response to prostaglandin D stimulus, inflammatory response, male sex determination, sleep integral to membrane, plasma membrane prostaglandin D receptor activity, prostaglandin J receptor activity, protein binding Human PTGDR2 Reactome UniProtKB {GO:0045745=GO_REF:0000019, GO:0019722=PMID:11208866, GO:0005886=Reactome:REACT_22289, GO:0004930=PMID:11208866, GO:0004956=PMID:11208866, GO:0007193=GO_REF:0000019, GO:0004958=GO_REF:0000019, GO:0004982=GO_REF:0000002, GO:0006955=PMID:9973380, GO:0006935=PMID:11208866, GO:0007186=PMID:11208866, GO:0005887=PMID:10036181, GO:0001785=GO_REF:0000019} Q9Y5Y4 Prostaglandin D2 receptor 2 protein 20090402 {GO:0045745=IEA, GO:0019722=IDA, GO:0005886=TAS, GO:0004930=IDA, GO:0004956=IDA, GO:0007193=IEA, GO:0004958=IEA, GO:0004982=IEA, GO:0006955=TAS, GO:0006935=IDA, GO:0007186=IDA, GO:0005887=TAS, GO:0001785=IEA} G-protein coupled receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, calcium-mediated signaling, chemotaxis, immune response, positive regulation of G-protein coupled receptor protein signaling pathway integral to plasma membrane, plasma membrane G-protein coupled receptor activity, N-formyl peptide receptor activity, prostaglandin D receptor activity, prostaglandin F receptor activity, prostaglandin J receptor activity Human PTGDS UniProtKB UniProtKB {GO:0019371=Reactome:REACT_150149, GO:0019369=Reactome:REACT_147851, GO:0006629=GO_REF:0000002, GO:0005791=PMID:9065498, GO:0005215=GO_REF:0000002, GO:0005504=PMID:20667974, GO:0031965=GO_REF:0000039, GO:0048471=GO_REF:0000039, GO:0005794=GO_REF:0000024, GO:0036094=GO_REF:0000002, GO:0045187=GO_REF:0000024, GO:0004667=PMID:20667974, GO:0005576=GO_REF:0000038, GO:0051384=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0005615=PMID:19878301, GO:0001516=PMID:20667974, GO:0005789=Reactome:REACT_150378, GO:0006810=GO_REF:0000024, GO:0005501=GO_REF:0000024} Q5SQ12 Prostaglandin-H2 D-isomerase protein 20130413 {GO:0019371=TAS, GO:0019369=TAS, GO:0006629=IEA, GO:0005791=IDA, GO:0005215=IEA, GO:0005504=IDA, GO:0031965=IEA, GO:0048471=IEA, GO:0005794=ISS, GO:0036094=IEA, GO:0045187=ISS, GO:0004667=IDA, GO:0005576=IEA, GO:0051384=IEA, GO:0044281=TAS, GO:0005615=IDA, GO:0001516=IDA, GO:0005789=TAS, GO:0006810=ISS, GO:0005501=ISS} arachidonic acid metabolic process, cyclooxygenase pathway, lipid metabolic process, prostaglandin biosynthetic process, regulation of circadian sleep/wake cycle, sleep, response to glucocorticoid stimulus, small molecule metabolic process, transport Golgi apparatus, endoplasmic reticulum membrane, extracellular region, extracellular space, nuclear membrane, perinuclear region of cytoplasm, rough endoplasmic reticulum fatty acid binding, prostaglandin-D synthase activity, retinoid binding, small molecule binding, transporter activity Human UniProtKB-KW:KW-0964 PTGER1 Reactome UniProtKB {GO:0005886=Reactome:REACT_22436, GO:0007186=PMID:8253813, GO:0005887=PMID:8253813, GO:0032496=GO_REF:0000019, GO:0004957=GO_REF:0000019} P34995 Prostaglandin E2 receptor EP1 subtype protein 20090402 {GO:0005886=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0032496=IEA, GO:0004957=IEA} G-protein coupled receptor signaling pathway, response to lipopolysaccharide integral to plasma membrane, plasma membrane prostaglandin E receptor activity Human PTGER2 BHF-UCL UniProtKB {GO:0005886=Reactome:REACT_22268, GO:0007186=PMID:10462542, GO:0005887=PMID:10462542, GO:0042127=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0007189=GO_REF:0000024, GO:0016021=GO_REF:0000002, GO:0071380=GO_REF:0000024, GO:0004957=GO_REF:0000019} P43116 Prostaglandin E2 receptor EP2 subtype protein 20120329 {GO:0005886=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0042127=IEA, GO:0032496=IEA, GO:0007189=ISS, GO:0016021=IEA, GO:0071380=ISS, GO:0004957=IEA} G-protein coupled receptor signaling pathway, adenylate cyclase-activating G-protein coupled receptor signaling pathway, cellular response to prostaglandin E stimulus, regulation of cell proliferation, response to lipopolysaccharide integral to membrane, integral to plasma membrane, plasma membrane prostaglandin E receptor activity Human UniProtKB:Q62053 PTGER3 InterPro UniProtKB {GO:0008219=PMID:10947062, GO:0005886=Reactome:REACT_22289, GO:0007200=GO_REF:0000019, GO:0005635=PMID:10336471, GO:0004957=GO_REF:0000002, GO:0007204=GO_REF:0000019, GO:0006351=PMID:10336471, GO:0031622=GO_REF:0000024, GO:0008150=GO_REF:0000015, GO:0007186=PMID:8307176, GO:0005887=PMID:8307176, GO:0001660=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0015701=GO_REF:0000019, GO:0007188=GO_REF:0000019, GO:0004879=PMID:10336471, GO:0016021=GO_REF:0000002, GO:0035810=GO_REF:0000019, GO:0030522=PMID:10336471} Q147X8 PTGER3 protein protein 20130413 {GO:0008219=TAS, GO:0005886=TAS, GO:0007200=IEA, GO:0005635=TAS, GO:0004957=IEA, GO:0007204=IEA, GO:0006351=TAS, GO:0031622=ISS, GO:0008150=ND, GO:0007186=TAS, GO:0005887=TAS, GO:0001660=IEA, GO:0032496=IEA, GO:0015701=IEA, GO:0007188=IEA, GO:0004879=TAS, GO:0016021=IEA, GO:0035810=IEA, GO:0030522=TAS} G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, bicarbonate transport, biological_process, cell death, elevation of cytosolic calcium ion concentration, fever generation, intracellular receptor signaling pathway, phospholipase C-activating G-protein coupled receptor signaling pathway, positive regulation of fever generation, positive regulation of urine volume, response to lipopolysaccharide, transcription, DNA-dependent integral to membrane, integral to plasma membrane, nuclear envelope, plasma membrane ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, prostaglandin E receptor activity Human InterPro:IPR000265|InterPro:IPR000276|InterPro:IPR001244|InterPro:IPR001481|InterPro:IPR008365|InterPro:IPR017452 PTGER4 Reactome UniProtKB {GO:0005515=PMID:16424369, GO:0005886=Reactome:REACT_22268, GO:0051492=GO_REF:0000024, GO:0007254=GO_REF:0000024, GO:0050715=GO_REF:0000024, GO:0050710=GO_REF:0000024, GO:0033624=PMID:21681739, GO:0004957=PMID:8163486, GO:2000420=PMID:21681739, GO:0009612=PMID:21723865, GO:0042093=GO_REF:0000024, GO:0060348=GO_REF:0000024, GO:0006955=PMID:8862514, GO:0030278=GO_REF:0000019, GO:0050728=PMID:16424369, GO:0050729=GO_REF:0000024, GO:0032496=GO_REF:0000019, GO:0007188=PMID:8163486, GO:0016021=PMID:8163486, GO:0071260=GO_REF:0000024, GO:0070371=GO_REF:0000024} P35408 Prostaglandin E2 receptor EP4 subtype protein 20090402 {GO:0005515=IPI, GO:0005886=TAS, GO:0051492=ISS, GO:0007254=ISS, GO:0050715=ISS, GO:0050710=ISS, GO:0033624=IDA, GO:0004957=IDA, GO:2000420=IDA, GO:0009612=IEP, GO:0042093=ISS, GO:0060348=ISS, GO:0006955=IEP, GO:0030278=IEA, GO:0050728=IDA, GO:0050729=ISS, GO:0032496=IEA, GO:0007188=IDA, GO:0016021=NAS, GO:0071260=ISS, GO:0070371=ISS} ERK1 and ERK2 cascade, JNK cascade, T-helper cell differentiation, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, bone development, cellular response to mechanical stimulus, immune response, negative regulation of cytokine secretion, negative regulation of eosinophil extravasation, negative regulation of inflammatory response, negative regulation of integrin activation, positive regulation of cytokine secretion, positive regulation of inflammatory response, regulation of ossification, regulation of stress fiber assembly, response to lipopolysaccharide, response to mechanical stimulus integral to membrane, plasma membrane prostaglandin E receptor activity, protein binding Human PTGES Reactome UniProtKB {GO:0019371=Reactome:REACT_150149, GO:0019369=Reactome:REACT_147851, GO:0014070=GO_REF:0000019, GO:0002526=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0006693=PMID:10377395, GO:0008285=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0002544=GO_REF:0000019, GO:0007165=PMID:10377395, GO:0051592=GO_REF:0000019, GO:0050220=Reactome:REACT_150407, GO:0043295=PMID:18682561, GO:0016020=PMID:10377395, GO:0001516=PMID:18682561, GO:0005641=GO_REF:0000019, GO:0005789=Reactome:REACT_150407, GO:0032496=GO_REF:0000019, GO:0032526=GO_REF:0000019, GO:0016021=PMID:18682561, GO:0034097=GO_REF:0000019} O14684 Prostaglandin E synthase protein 20120508 {GO:0019371=TAS, GO:0019369=TAS, GO:0014070=IEA, GO:0002526=IEA, GO:0048471=IEA, GO:0006693=TAS, GO:0008285=IEA, GO:0044281=TAS, GO:0002544=IEA, GO:0007165=NAS, GO:0051592=IEA, GO:0050220=EXP, GO:0043295=IDA, GO:0016020=TAS, GO:0001516=IDA, GO:0005641=IEA, GO:0005789=TAS, GO:0032496=IEA, GO:0032526=IEA, GO:0016021=IDA, GO:0034097=IEA} acute inflammatory response, arachidonic acid metabolic process, chronic inflammatory response, cyclooxygenase pathway, negative regulation of cell proliferation, prostaglandin biosynthetic process, prostaglandin metabolic process, response to calcium ion, response to cytokine stimulus, response to lipopolysaccharide, response to organic cyclic compound, response to retinoic acid, signal transduction, small molecule metabolic process endoplasmic reticulum membrane, integral to membrane, membrane, nuclear envelope lumen, perinuclear region of cytoplasm glutathione binding, prostaglandin-E synthase activity Human PTGES2 LIFEdb UniProtKB {GO:0048471=GO_REF:0000039, GO:0015035=GO_REF:0000002, GO:0009055=GO_REF:0000002, GO:0005634=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0046903=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0005739=GO_REF:0000054, GO:0050220=GO_REF:0000003, GO:0001516=GO_REF:0000041, GO:0000139=GO_REF:0000039, GO:0045454=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0045893=GO_REF:0000019} Q9H7Z7 Prostaglandin E synthase 2 protein 20100607 {GO:0048471=IEA, GO:0015035=IEA, GO:0009055=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0046903=IEA, GO:0005829=IEA, GO:0005739=IDA, GO:0050220=IEA, GO:0001516=IEA, GO:0000139=IEA, GO:0045454=IEA, GO:0016021=IEA, GO:0045893=IEA} cell redox homeostasis, positive regulation of transcription, DNA-dependent, prostaglandin biosynthetic process, secretion Golgi membrane, cytosol, integral to membrane, mitochondrion, nucleus, perinuclear region of cytoplasm DNA binding, electron carrier activity, prostaglandin-E synthase activity, protein disulfide oxidoreductase activity Human PTGES3 HPA UniProtKB {GO:0005515=PMID:21988832, GO:0019371=Reactome:REACT_150149, GO:0019369=Reactome:REACT_147851, GO:0005697=PMID:12135483, GO:0000781=PMID:12135483, GO:0003720=PMID:12135483, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_15459, GO:0007165=PMID:8114727, GO:0005737=GO_REF:0000052, GO:0050220=PMID:10922363, GO:0000723=PMID:12135483, GO:0001516=PMID:10922363, GO:0070389=PMID:12853476, GO:0051082=PMID:12077419} Q15185 Prostaglandin E synthase 3 protein 20110516 {GO:0005515=IPI, GO:0019371=TAS, GO:0019369=TAS, GO:0005697=IDA, GO:0000781=IC, GO:0003720=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0005829=TAS, GO:0007165=TAS, GO:0005737=IDA, GO:0050220=IDA, GO:0000723=TAS, GO:0001516=IDA, GO:0070389=IDA, GO:0051082=IDA} arachidonic acid metabolic process, chaperone cofactor-dependent protein refolding, cyclooxygenase pathway, prostaglandin biosynthetic process, signal transduction, small molecule metabolic process, telomere maintenance chromosome, telomeric region, cytoplasm, cytosol, nucleolus, nucleus, telomerase holoenzyme complex prostaglandin-E synthase activity, protein binding, telomerase activity, unfolded protein binding Human PTGFR Reactome UniProtKB {GO:0043066=GO_REF:0000019, GO:0005886=Reactome:REACT_22436, GO:0007567=PMID:9918852, GO:0007186=PMID:8300593, GO:0005887=PMID:8300593, GO:0032496=GO_REF:0000019, GO:0005576=PMID:10575000, GO:0016021=GO_REF:0000038, GO:0004958=GO_REF:0000002} P43088 Prostaglandin F2-alpha receptor protein 20090402 {GO:0043066=IEA, GO:0005886=TAS, GO:0007567=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0032496=IEA, GO:0005576=IDA, GO:0016021=IEA, GO:0004958=IEA} G-protein coupled receptor signaling pathway, negative regulation of apoptotic process, parturition, response to lipopolysaccharide extracellular region, integral to membrane, integral to plasma membrane, plasma membrane prostaglandin F receptor activity Human PTGFRN UniProtKB UniProtKB {GO:0005515=PMID:11278880, GO:0005794=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0034389=GO_REF:0000019} Q9P2B2 Prostaglandin F2 receptor negative regulator protein 20050707 {GO:0005515=IPI, GO:0005794=IEA, GO:0005789=IEA, GO:0016021=IEA, GO:0034389=IEA} lipid particle organization Golgi apparatus, endoplasmic reticulum membrane, integral to membrane protein binding Human UniProtKB:P21926 PTGIR Reactome UniProtKB {GO:0005085=Reactome:REACT_23823, GO:0005886=Reactome:REACT_23938, GO:0007186=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0007187=PMID:7512962, GO:0005887=PMID:7512962, GO:0004930=GO_REF:0000037, GO:0007267=PMID:7512962, GO:0032496=GO_REF:0000019, GO:0016021=GO_REF:0000002} P43119 Prostacyclin receptor protein 20090402 {GO:0005085=TAS, GO:0005886=TAS, GO:0007186=IEA, GO:0007596=TAS, GO:0007187=TAS, GO:0005887=TAS, GO:0004930=IEA, GO:0007267=TAS, GO:0032496=IEA, GO:0016021=IEA} G-protein coupled receptor signaling pathway, G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, blood coagulation, cell-cell signaling, response to lipopolysaccharide integral to membrane, integral to plasma membrane, plasma membrane G-protein coupled receptor activity, guanyl-nucleotide exchange factor activity Human PTGIS Reactome UniProtKB {GO:0005515=PMID:20122998, GO:0019369=Reactome:REACT_147851, GO:0006805=Reactome:REACT_13705, GO:0005783=PMID:21035466, GO:0005634=PMID:21035466, GO:0044281=Reactome:REACT_111217, GO:0005615=GO_REF:0000024, GO:0006690=Reactome:REACT_13645, GO:0004497=GO_REF:0000002, GO:0035360=PMID:11551955, GO:0045019=PMID:20159982, GO:0071354=PMID:8185632, GO:0019371=Reactome:REACT_150149, GO:0043065=PMID:11551955, GO:0005506=GO_REF:0000002, GO:0071456=PMID:21296955, GO:0009055=GO_REF:0000002, GO:0032088=PMID:20159982, GO:0045766=PMID:20122998, GO:0005901=PMID:20122998, GO:0050728=PMID:20159982, GO:0071347=PMID:8185632, GO:0005789=Reactome:REACT_1841, GO:0016021=GO_REF:0000037, GO:0016705=GO_REF:0000002, GO:0020037=PMID:17020766} Q16647 Prostacyclin synthase protein 20130301 {GO:0005515=IPI, GO:0019369=TAS, GO:0006805=TAS, GO:0005783=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0005615=ISS, GO:0006690=TAS, GO:0004497=IEA, GO:0035360=IDA, GO:0045019=IDA, GO:0071354=IEP, GO:0019371=TAS, GO:0043065=IDA, GO:0005506=IEA, GO:0071456=IDA, GO:0009055=IEA, GO:0032088=IDA, GO:0045766=IMP, GO:0005901=IDA, GO:0050728=IDA, GO:0071347=IEP, GO:0005789=TAS, GO:0016021=IEA, GO:0016705=IEA, GO:0020037=IDA} arachidonic acid metabolic process, cellular response to hypoxia, cellular response to interleukin-1, cellular response to interleukin-6, cyclooxygenase pathway, icosanoid metabolic process, negative regulation of NF-kappaB transcription factor activity, negative regulation of inflammatory response, negative regulation of nitric oxide biosynthetic process, positive regulation of angiogenesis, positive regulation of apoptotic process, positive regulation of peroxisome proliferator activated receptor signaling pathway, small molecule metabolic process, xenobiotic metabolic process caveola, endoplasmic reticulum, endoplasmic reticulum membrane, extracellular space, integral to membrane, nucleus electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, protein binding Human PTGR1 InterPro UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0019371=Reactome:REACT_150149, GO:0047522=GO_REF:0000003, GO:0009636=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0006691=Reactome:REACT_150420, GO:0032440=GO_REF:0000003, GO:0036132=GO_REF:0000003, GO:0004022=GO_REF:0000029, GO:0005737=GO_REF:0000029, GO:0016491=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:2001300=Reactome:REACT_150320} Q5JVP3 Leukotriene B4 12-hydroxydehydrogenase, isoform CRA_d protein 20130413 {GO:0019369=TAS, GO:0019371=TAS, GO:0047522=IEA, GO:0009636=IEA, GO:0044281=TAS, GO:0006691=TAS, GO:0032440=IEA, GO:0036132=IEA, GO:0004022=NAS, GO:0005737=NAS, GO:0016491=IEA, GO:0008270=IEA, GO:2001300=TAS} arachidonic acid metabolic process, cyclooxygenase pathway, leukotriene metabolic process, lipoxin metabolic process, response to toxic substance, small molecule metabolic process cytoplasm "13-prostaglandin reductase activity, 15-oxoprostaglandin 13-oxidase activity, 2-alkenal reductase NAD(P)"" activity, alcohol dehydrogenase (NAD) activity, oxidoreductase activity, zinc ion binding""" Human InterPro:IPR002085|InterPro:IPR013149 PTGS1 BHF-UCL UniProtKB {GO:0019371=PMID:1380156, GO:0019369=Reactome:REACT_147851, GO:0006629=PMID:1907252, GO:0006805=Reactome:REACT_13705, GO:0004666=PMID:1380156, GO:0005634=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0043231=GO_REF:0000024, GO:0044444=PMID:12355421, GO:0005737=GO_REF:0000024, GO:0004601=Reactome:REACT_810, GO:0001516=GO_REF:0000024, GO:0042127=GO_REF:0000019, GO:0005789=Reactome:REACT_150159, GO:0008217=GO_REF:0000024, GO:0016702=GO_REF:0000037, GO:0006979=GO_REF:0000002, GO:0020037=GO_REF:0000002, GO:0001750=GO_REF:0000019} P23219 Prostaglandin G/H synthase 1 protein 20100528 {GO:0019371=IDA, GO:0019369=TAS, GO:0006629=NAS, GO:0006805=TAS, GO:0004666=IDA, GO:0005634=ISS, GO:0044281=TAS, GO:0046872=IEA, GO:0043231=ISS, GO:0044444=IDA, GO:0005737=ISS, GO:0004601=TAS, GO:0001516=ISS, GO:0042127=IEA, GO:0005789=TAS, GO:0008217=ISS, GO:0016702=IEA, GO:0006979=IEA, GO:0020037=IEA, GO:0001750=IEA} arachidonic acid metabolic process, cyclooxygenase pathway, lipid metabolic process, prostaglandin biosynthetic process, regulation of blood pressure, regulation of cell proliferation, response to oxidative stress, small molecule metabolic process, xenobiotic metabolic process cytoplasm, cytoplasmic part, endoplasmic reticulum membrane, intracellular membrane-bounded organelle, nucleus, photoreceptor outer segment heme binding, metal ion binding, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, peroxidase activity, prostaglandin-endoperoxide synthase activity Human PTGS2 BHF-UCL UniProtKB {GO:0019369=Reactome:REACT_147851, GO:0006693=PMID:9630216, GO:0035633=GO_REF:0000019, GO:0042640=GO_REF:0000019, GO:0010042=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0071636=PMID:9630216, GO:0031622=GO_REF:0000024, GO:0034644=GO_REF:0000019, GO:0004601=PMID:14511332, GO:0001516=PMID:20448152, GO:0032496=GO_REF:0000019, GO:0090050=PMID:9630216, GO:0007613=GO_REF:0000019, GO:0051926=GO_REF:0000019, GO:0090362=GO_REF:0000024, GO:0007612=GO_REF:0000019, GO:0032355=GO_REF:0000019, GO:0006979=GO_REF:0000002, GO:0007566=GO_REF:0000019, GO:0031394=PMID:20448152, GO:0051968=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0045786=GO_REF:0000019, GO:0071318=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0070542=GO_REF:0000019, GO:0050873=GO_REF:0000019, GO:0032227=GO_REF:0000019, GO:0005789=Reactome:REACT_150446, GO:0019899=PMID:16373578, GO:0020037=GO_REF:0000024, GO:0043005=PMID:12355421, GO:0042346=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0006928=PMID:9630216, GO:0033280=GO_REF:0000019, GO:0005634=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0030282=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0045429=PMID:9630216, GO:0008289=GO_REF:0000019, GO:0046697=GO_REF:0000019, GO:0005737=PMID:14511332, GO:0006954=GO_REF:0000019, GO:0031915=GO_REF:0000019, GO:0045907=GO_REF:0000019, GO:0045986=GO_REF:0000019, GO:0045987=GO_REF:0000019, GO:0019371=PMID:1380156, GO:0043065=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0019372=Reactome:REACT_150422, GO:0050727=PMID:14511332, GO:0071456=PMID:21296955, GO:0004666=PMID:1380156, GO:0001525=GO_REF:0000019, GO:0090336=PMID:20448152, GO:0090271=PMID:9630216, GO:0010575=PMID:9630216, GO:0048661=GO_REF:0000019, GO:0019233=GO_REF:0000019, GO:0010226=GO_REF:0000019, GO:0009750=GO_REF:0000019, GO:0008217=GO_REF:0000024, GO:0034612=GO_REF:0000019, GO:0071260=GO_REF:0000019, GO:0030728=GO_REF:0000019, GO:0050473=Reactome:REACT_150372} P35354 Prostaglandin G/H synthase 2 protein 20110110 {GO:0019369=TAS, GO:0006693=TAS, GO:0035633=IEA, GO:0042640=IEA, GO:0010042=IEA, GO:0042803=IEA, GO:0071636=ISS, GO:0031622=ISS, GO:0034644=IEA, GO:0004601=NAS, GO:0001516=NAS, GO:0032496=IEA, GO:0090050=ISS, GO:0007613=IEA, GO:0051926=IEA, GO:0090362=ISS, GO:0007612=IEA, GO:0032355=IEA, GO:0006979=IEA, GO:0007566=IEA, GO:0031394=NAS, GO:0051968=IEA, GO:0051384=IEA, GO:0045786=IEA, GO:0071318=IEA, GO:0043234=IEA, GO:0070542=IEA, GO:0050873=IEA, GO:0032227=IEA, GO:0005789=TAS, GO:0019899=IPI, GO:0020037=ISS, GO:0043005=IDA, GO:0042346=IEA, GO:0008285=IEA, GO:0006928=TAS, GO:0033280=IEA, GO:0005634=ISS, GO:0044281=TAS, GO:0030282=IEA, GO:0046872=IEA, GO:0045429=ISS, GO:0008289=IEA, GO:0046697=IEA, GO:0005737=IDA, GO:0006954=IEA, GO:0031915=IEA, GO:0045907=IEA, GO:0045986=IEA, GO:0045987=IEA, GO:0019371=IDA, GO:0043065=IEA, GO:0042493=IEA, GO:0019372=TAS, GO:0050727=NAS, GO:0071456=IEP, GO:0004666=IDA, GO:0001525=IEA, GO:0090336=ISS, GO:0090271=ISS, GO:0010575=ISS, GO:0048661=IEA, GO:0019233=IEA, GO:0010226=IEA, GO:0009750=IEA, GO:0008217=ISS, GO:0034612=IEA, GO:0071260=IEA, GO:0030728=IEA, GO:0050473=TAS} anagen, angiogenesis, arachidonic acid metabolic process, bone mineralization, brown fat cell differentiation, cellular component movement, cellular response to ATP, cellular response to UV, cellular response to hypoxia, cellular response to mechanical stimulus, cyclooxygenase pathway, decidualization, embryo implantation, inflammatory response, learning, lipoxygenase pathway, maintenance of blood-brain barrier, memory, negative regulation of calcium ion transport, negative regulation of cell cycle, negative regulation of cell proliferation, negative regulation of smooth muscle contraction, negative regulation of synaptic transmission, dopaminergic, ovulation, positive regulation of NF-kappaB import into nucleus, positive regulation of apoptotic process, positive regulation of brown fat cell differentiation, positive regulation of cell migration involved in sprouting angiogenesis, positive regulation of fever generation, positive regulation of fibroblast growth factor production, positive regulation of nitric oxide biosynthetic process, positive regulation of platelet-derived growth factor production, positive regulation of prostaglandin biosynthetic process, positive regulation of smooth muscle cell proliferation, positive regulation of smooth muscle contraction, positive regulation of synaptic plasticity, positive regulation of synaptic transmission, glutamatergic, positive regulation of transforming growth factor beta production, positive regulation of vasoconstriction, positive regulation vascular endothelial growth factor production, prostaglandin biosynthetic process, prostaglandin metabolic process, regulation of blood pressure, regulation of inflammatory response, response to drug, response to estradiol stimulus, response to fatty acid, response to fructose stimulus, response to glucocorticoid stimulus, response to lipopolysaccharide, response to lithium ion, response to manganese ion, response to oxidative stress, response to tumor necrosis factor, response to vitamin D, sensory perception of pain, small molecule metabolic process cytoplasm, endoplasmic reticulum membrane, neuron projection, nucleus, protein complex arachidonate 15-lipoxygenase activity, enzyme binding, heme binding, lipid binding, metal ion binding, peroxidase activity, prostaglandin-endoperoxide synthase activity, protein homodimerization activity Human UniProtKB:Q05769 PTH Reactome UniProtKB {GO:0010468=PMID:90087, GO:0030501=PMID:17696759, GO:0045725=PMID:21076856, GO:0046058=PMID:9927325, GO:0003705=PMID:17696759, GO:0045453=PMID:15080150, GO:0030819=PMID:90087, GO:0007267=PMID:7721880, GO:0006874=GO_REF:0000029, GO:0031856=GO_REF:0000019, GO:0009967=GO_REF:0000019, GO:0005576=Reactome:REACT_22268, GO:0000122=PMID:17696759, GO:0007266=GO_REF:0000019, GO:0051428=PMID:19674967, GO:0005615=GO_REF:0000019, GO:0001501=PMID:10913913, GO:0007186=PMID:7797535, GO:0005179=GO_REF:0000019, GO:0034645=PMID:19723499, GO:0045944=PMID:19723499, GO:0046326=PMID:21076856, GO:0007189=GO_REF:0000019, GO:0008628=PMID:10913913} P01270 Parathyroid hormone protein 20090512 {GO:0010468=IDA, GO:0030501=IDA, GO:0045725=IDA, GO:0046058=TAS, GO:0003705=IMP, GO:0045453=NAS, GO:0030819=IDA, GO:0007267=TAS, GO:0006874=NAS, GO:0031856=IEA, GO:0009967=IEA, GO:0005576=TAS, GO:0000122=IDA, GO:0007266=IEA, GO:0051428=IDA, GO:0005615=IEA, GO:0001501=TAS, GO:0007186=TAS, GO:0005179=IEA, GO:0034645=IDA, GO:0045944=IDA, GO:0046326=IDA, GO:0007189=IEA, GO:0008628=TAS} G-protein coupled receptor signaling pathway, Rho protein signal transduction, adenylate cyclase-activating G-protein coupled receptor signaling pathway, bone resorption, cAMP metabolic process, cell-cell signaling, cellular calcium ion homeostasis, cellular macromolecule biosynthetic process, hormone-mediated apoptotic signaling pathway, negative regulation of transcription from RNA polymerase II promoter, positive regulation of bone mineralization, positive regulation of cAMP biosynthetic process, positive regulation of glucose import, positive regulation of glycogen biosynthetic process, positive regulation of signal transduction, positive regulation of transcription from RNA polymerase II promoter, regulation of gene expression, skeletal system development extracellular region, extracellular space RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, hormone activity, parathyroid hormone receptor binding, peptide hormone receptor binding Human PTH1R BHF-UCL UniProtKB {GO:0008284=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0005886=Reactome:REACT_22268, GO:0045453=GO_REF:0000019, GO:0060732=GO_REF:0000024, GO:0007200=PMID:19608645, GO:0005634=GO_REF:0000019, GO:0030282=GO_REF:0000019, GO:0031526=GO_REF:0000019, GO:0043621=PMID:19674967, GO:0007204=GO_REF:0000019, GO:0016323=GO_REF:0000024, GO:0005737=GO_REF:0000019, GO:0016324=GO_REF:0000024, GO:0004991=PMID:19674967, GO:0002062=GO_REF:0000019, GO:0048469=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0043235=GO_REF:0000024, GO:0001501=PMID:9745456, GO:0007186=PMID:9745456, GO:0002076=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0007187=PMID:9927325, GO:0005887=PMID:19674967, GO:0007188=PMID:19674967, GO:0007189=GO_REF:0000024, GO:0016021=GO_REF:0000038, GO:0017046=PMID:19674967} Q03431 Parathyroid hormone/parathyroid hormone-related peptide receptor protein 20120511 {GO:0008284=IEA, GO:0008285=IEA, GO:0005886=TAS, GO:0045453=IEA, GO:0060732=ISS, GO:0007200=IC, GO:0005634=IEA, GO:0030282=IEA, GO:0031526=IEA, GO:0043621=IDA, GO:0007204=IEA, GO:0016323=ISS, GO:0005737=IEA, GO:0016324=ISS, GO:0004991=IDA, GO:0002062=IEA, GO:0048469=IEA, GO:0007568=IEA, GO:0043235=ISS, GO:0001501=TAS, GO:0007186=TAS, GO:0002076=IEA, GO:0016020=IEA, GO:0007187=TAS, GO:0005887=IDA, GO:0007188=IDA, GO:0007189=ISS, GO:0016021=IEA, GO:0017046=IDA} G-protein coupled receptor signaling pathway, G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, aging, bone mineralization, bone resorption, cell maturation, chondrocyte differentiation, elevation of cytosolic calcium ion concentration, negative regulation of cell proliferation, osteoblast development, phospholipase C-activating G-protein coupled receptor signaling pathway, positive regulation of cell proliferation, positive regulation of inositol phosphate biosynthetic process, skeletal system development apical plasma membrane, basolateral plasma membrane, brush border membrane, cytoplasm, integral to membrane, integral to plasma membrane, membrane, nucleus, plasma membrane, receptor complex parathyroid hormone receptor activity, peptide hormone binding, protein self-association Human GO:0060732 PTH2 Reactome UniProtKB {GO:0007218=GO_REF:0000037, GO:0005576=Reactome:REACT_22268} Q96A98 Tuberoinfundibular peptide of 39 residues protein 20090512 {GO:0007218=IEA, GO:0005576=TAS} neuropeptide signaling pathway extracellular region Human PTH2R Reactome UniProtKB {GO:0005886=Reactome:REACT_22268, GO:0007186=PMID:7797535, GO:0004991=PMID:7797535, GO:0016020=GO_REF:0000002, GO:0005887=PMID:7797535, GO:0004930=GO_REF:0000002} P49190 Parathyroid hormone 2 receptor protein 20090512 {GO:0005886=TAS, GO:0007186=TAS, GO:0004991=TAS, GO:0016020=IEA, GO:0005887=TAS, GO:0004930=IEA} G-protein coupled receptor signaling pathway integral to plasma membrane, membrane, plasma membrane G-protein coupled receptor activity, parathyroid hormone receptor activity Human PTHLH HPA UniProtKB {GO:0010468=PMID:90087, GO:0008284=GO_REF:0000019, GO:0008285=PMID:8058749, GO:0030819=PMID:90087, GO:0007267=PMID:2549037, GO:0005634=GO_REF:0000052, GO:0051428=PMID:19674967, GO:0005615=PMID:8641188, GO:0043433=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0016485=GO_REF:0000019, GO:0060649=GO_REF:0000019, GO:0030855=GO_REF:0000019, GO:0043129=GO_REF:0000019, GO:0032331=PMID:90087, GO:0007565=PMID:10828849, GO:0005794=GO_REF:0000052, GO:0048286=GO_REF:0000019, GO:0046058=PMID:2549037, GO:0005730=GO_REF:0000052, GO:0005576=Reactome:REACT_22268, GO:0032330=GO_REF:0000002, GO:0060659=GO_REF:0000019, GO:0001501=PMID:9008714, GO:0001958=GO_REF:0000019, GO:0007492=GO_REF:0000019, GO:0002076=GO_REF:0000019, GO:0008544=PMID:8058749, GO:0005179=GO_REF:0000037, GO:0007189=PMID:9832460} P12272 Parathyroid hormone-related protein protein 20110516 {GO:0010468=IDA, GO:0008284=IEA, GO:0008285=TAS, GO:0030819=IDA, GO:0007267=TAS, GO:0005634=IDA, GO:0051428=IDA, GO:0005615=TAS, GO:0043433=IEA, GO:0005737=IDA, GO:0016485=IEA, GO:0060649=IEA, GO:0030855=IEA, GO:0043129=IEA, GO:0032331=IDA, GO:0007565=TAS, GO:0005794=IDA, GO:0048286=IEA, GO:0046058=TAS, GO:0005730=IDA, GO:0005576=TAS, GO:0032330=IEA, GO:0060659=IEA, GO:0001501=IDA, GO:0001958=IEA, GO:0007492=IEA, GO:0002076=IEA, GO:0008544=TAS, GO:0005179=IEA, GO:0007189=IDA} adenylate cyclase-activating G-protein coupled receptor signaling pathway, cAMP metabolic process, cell-cell signaling, endochondral ossification, endoderm development, epidermis development, epithelial cell differentiation, female pregnancy, lung alveolus development, mammary gland bud elongation, negative regulation of cell proliferation, negative regulation of chondrocyte differentiation, negative regulation of sequence-specific DNA binding transcription factor activity, nipple sheath formation, osteoblast development, positive regulation of cAMP biosynthetic process, positive regulation of cell proliferation, protein processing, regulation of chondrocyte differentiation, regulation of gene expression, skeletal system development, surfactant homeostasis Golgi apparatus, cytoplasm, extracellular region, extracellular space, nucleolus, nucleus hormone activity, peptide hormone receptor binding Human PTK2 UniProtKB UniProtKB {GO:0005515=PMID:22402981, GO:0046685=GO_REF:0000019, GO:0030307=GO_REF:0000019, GO:0008360=PMID:10655584, GO:0030010=PMID:19525103, GO:0009790=PMID:20552554, GO:0007172=GO_REF:0000002, GO:0046777=PMID:10655584, GO:0043552=PMID:15725728, GO:0007411=Reactome:REACT_18266, GO:0030198=GO_REF:0000019, GO:0042127=PMID:18206965, GO:0045860=PMID:11331870, GO:0045444=GO_REF:0000019, GO:0032319=PMID:19525103, GO:0005856=GO_REF:0000002, GO:0005938=GO_REF:0000039, GO:0032355=GO_REF:0000019, GO:0042169=PMID:15077193, GO:0022408=PMID:21703394, GO:0030336=GO_REF:0000019, GO:0030335=PMID:21703394, GO:0051964=GO_REF:0000019, GO:0019901=PMID:19118217, GO:0005815=GO_REF:0000039, GO:0030168=Reactome:REACT_798, GO:0010243=GO_REF:0000019, GO:0018108=PMID:10655584, GO:0014068=PMID:15166238, GO:0001890=PMID:20552554, GO:0030027=GO_REF:0000019, GO:0045785=GO_REF:0000019, GO:0005178=GO_REF:0000019, GO:0051493=PMID:15725728, GO:0030644=GO_REF:0000019, GO:0007229=PMID:11331870, GO:0043542=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0050806=GO_REF:0000019, GO:0050771=GO_REF:0000019, GO:0038096=Reactome:REACT_160123, GO:0005925=GO_REF:0000002, GO:0043548=GO_REF:0000019, GO:0033628=PMID:10655584, GO:0051897=PMID:15166238, GO:0008284=GO_REF:0000024, GO:0060396=PMID:10925297, GO:0005634=PMID:15855171, GO:0051893=PMID:19525103, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_160238, GO:0014911=GO_REF:0000019, GO:0016323=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0050766=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0010594=PMID:20552554, GO:0038007=PMID:15725728, GO:0014704=GO_REF:0000019, GO:0048870=PMID:15725728, GO:0045909=GO_REF:0000019, GO:0004871=GO_REF:0000002, GO:0008432=PMID:10925297, GO:0046621=GO_REF:0000019, GO:0043066=PMID:15166238, GO:0048013=PMID:10655584, GO:0042493=GO_REF:0000019, GO:0021955=GO_REF:0000019, GO:0005730=GO_REF:0000019, GO:0007254=GO_REF:0000019, GO:0006915=Reactome:REACT_578, GO:0000226=GO_REF:0000019, GO:0001525=PMID:20552554, GO:0060252=GO_REF:0000019, GO:0048661=GO_REF:0000019, GO:0005524=GO_REF:0000038, GO:0009612=GO_REF:0000019, GO:0009749=GO_REF:0000019, GO:0042383=GO_REF:0000019, GO:0016604=GO_REF:0000019, GO:0045667=PMID:16927379, GO:0003007=PMID:20552554, GO:2000060=GO_REF:0000024, GO:0040023=GO_REF:0000019, GO:0004672=Reactome:REACT_15535, GO:0007596=Reactome:REACT_604, GO:0001934=PMID:15166238, GO:0004713=GO_REF:0000038, GO:0001764=GO_REF:0000019, GO:0004715=PMID:10655584, GO:0001570=GO_REF:0000019} Q8N9D7 cDNA FLJ37680 fis, clone BRHIP2012923, highly similar to FOCAL ADHESION KINASE 1 (EC 2.7.1.112) protein 20130413 {GO:0005515=IPI, GO:0046685=IEA, GO:0030307=IEA, GO:0008360=IMP, GO:0030010=TAS, GO:0009790=TAS, GO:0007172=IEA, GO:0046777=IDA, GO:0043552=TAS, GO:0007411=TAS, GO:0030198=IEA, GO:0042127=IMP, GO:0045860=IMP, GO:0045444=IEA, GO:0032319=TAS, GO:0005856=IEA, GO:0005938=IEA, GO:0032355=IEA, GO:0042169=IPI, GO:0022408=IDA, GO:0030336=IEA, GO:0030335=IDA, GO:0051964=IEA, GO:0019901=IPI, GO:0005815=IEA, GO:0030168=TAS, GO:0010243=IEA, GO:0018108=IDA, GO:0014068=IMP, GO:0001890=TAS, GO:0030027=IEA, GO:0045785=IEA, GO:0005178=IEA, GO:0051493=TAS, GO:0030644=IEA, GO:0007229=IMP, GO:0043542=IEA, GO:0045087=TAS, GO:0050806=IEA, GO:0050771=IEA, GO:0038096=TAS, GO:0005925=IEA, GO:0043548=IEA, GO:0033628=IDA, GO:0051897=IMP, GO:0008284=ISS, GO:0060396=IDA, GO:0005634=IDA, GO:0051893=TAS, GO:0006921=TAS, GO:0005829=TAS, GO:0014911=IEA, GO:0016323=IEA, GO:0016324=IEA, GO:0050766=IEA, GO:0005737=IDA, GO:0010594=TAS, GO:0038007=TAS, GO:0014704=IEA, GO:0048870=TAS, GO:0045909=IEA, GO:0004871=IEA, GO:0008432=IDA, GO:0046621=IEA, GO:0043066=IMP, GO:0048013=IDA, GO:0042493=IEA, GO:0021955=IEA, GO:0005730=IEA, GO:0007254=IEA, GO:0006915=TAS, GO:0000226=IEA, GO:0001525=TAS, GO:0060252=IEA, GO:0048661=IEA, GO:0005524=IEA, GO:0009612=IEA, GO:0009749=IEA, GO:0042383=IEA, GO:0016604=IEA, GO:0045667=IMP, GO:0003007=TAS, GO:2000060=ISS, GO:0040023=IEA, GO:0004672=TAS, GO:0007596=TAS, GO:0001934=IMP, GO:0004713=IEA, GO:0001764=IEA, GO:0004715=IDA, GO:0001570=IEA} Fc-gamma receptor signaling pathway involved in phagocytosis, JNK cascade, angiogenesis, apoptotic process, axon guidance, blood coagulation, cell motility, cellular chloride ion homeostasis, cellular component disassembly involved in execution phase of apoptosis, central nervous system neuron axonogenesis, embryo development, endothelial cell migration, ephrin receptor signaling pathway, establishment of cell polarity, establishment of nucleus localization, extracellular matrix organization, fat cell differentiation, growth hormone receptor signaling pathway, heart morphogenesis, innate immune response, integrin-mediated signaling pathway, microtubule cytoskeleton organization, negative regulation of apoptotic process, negative regulation of axonogenesis, negative regulation of cell migration, negative regulation of cell-cell adhesion, negative regulation of organ growth, negative regulation of synapse assembly, netrin-activated signaling pathway, neuron migration, peptidyl-tyrosine phosphorylation, placenta development, platelet activation, positive regulation of cell adhesion, positive regulation of cell growth, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of glial cell proliferation, positive regulation of phagocytosis, positive regulation of phosphatidylinositol 3-kinase activity, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of protein kinase B signaling cascade, positive regulation of protein kinase activity, positive regulation of protein phosphorylation, positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process, positive regulation of smooth muscle cell migration, positive regulation of smooth muscle cell proliferation, positive regulation of synaptic transmission, positive regulation of vasodilation, protein autophosphorylation, regulation of Rho GTPase activity, regulation of cell adhesion mediated by integrin, regulation of cell proliferation, regulation of cell shape, regulation of cytoskeleton organization, regulation of endothelial cell migration, regulation of focal adhesion assembly, regulation of osteoblast differentiation, response to arsenic-containing substance, response to drug, response to estradiol stimulus, response to glucose stimulus, response to mechanical stimulus, response to organic nitrogen, signal complex assembly, vasculogenesis apical plasma membrane, basolateral plasma membrane, cell cortex, cytoplasm, cytoskeleton, cytosol, focal adhesion, intercalated disc, lamellipodium, microtubule organizing center, nuclear body, nucleolus, nucleus, sarcolemma ATP binding, JUN kinase binding, SH2 domain binding, integrin binding, non-membrane spanning protein tyrosine kinase activity, phosphatidylinositol 3-kinase binding, protein binding, protein kinase activity, protein kinase binding, protein tyrosine kinase activity, signal transducer activity Human UniProtKB-KW:KW-0067 PTK2B BHF-UCL UniProtKB {GO:0005515=PMID:18086875, GO:0030307=GO_REF:0000019, GO:0071300=PMID:17910947, GO:0045453=GO_REF:0000024, GO:0043267=PMID:7544443, GO:0046330=PMID:8670418, GO:0050731=PMID:21245381, GO:0030155=PMID:19086031, GO:0046777=PMID:8849729, GO:0000165=GO_REF:0000019, GO:0045860=PMID:7544443, GO:0050848=GO_REF:0000019, GO:0006950=PMID:8939945, GO:0018108=PMID:7544443, GO:0032863=GO_REF:0000019, GO:0030502=GO_REF:0000024, GO:0010595=PMID:21245381, GO:0051000=GO_REF:0000019, GO:0002315=GO_REF:0000024, GO:0032960=GO_REF:0000024, GO:0030424=GO_REF:0000019, GO:0048471=PMID:18765415, GO:0042976=PMID:8670418, GO:0045471=GO_REF:0000019, GO:0043149=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0030426=GO_REF:0000019, GO:0014009=GO_REF:0000019, GO:0005829=Reactome:REACT_27192, GO:0004871=GO_REF:0000002, GO:0009725=GO_REF:0000019, GO:0048010=PMID:21245381, GO:0042493=GO_REF:0000019, GO:2000114=GO_REF:0000024, GO:0045727=GO_REF:0000019, GO:0006970=GO_REF:0000019, GO:0043423=GO_REF:0000019, GO:0009612=GO_REF:0000019, GO:0010226=GO_REF:0000019, GO:0030826=GO_REF:0000019, GO:0042542=GO_REF:0000019, GO:0008360=PMID:19086031, GO:0001556=GO_REF:0000019, GO:0042220=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0051591=GO_REF:0000019, GO:0031175=GO_REF:0000019, GO:2000249=GO_REF:0000024, GO:0007172=GO_REF:0000002, GO:0043552=GO_REF:0000024, GO:0007173=GO_REF:0000019, GO:0030838=PMID:18765415, GO:0070374=PMID:7544443, GO:0005856=GO_REF:0000002, GO:0005938=GO_REF:0000039, GO:0070098=GO_REF:0000024, GO:0030335=PMID:18765415, GO:0014069=GO_REF:0000019, GO:0030027=PMID:18765415, GO:0033209=PMID:8670418, GO:0010752=GO_REF:0000019, GO:0051592=GO_REF:0000019, GO:0043534=GO_REF:0000019, GO:0007229=PMID:15050747, GO:0010976=PMID:17910947, GO:0045121=GO_REF:0000019, GO:0010758=GO_REF:0000024, GO:0005925=PMID:18765415, GO:2000379=GO_REF:0000019, GO:0001954=PMID:18765415, GO:0045428=GO_REF:0000019, GO:0008284=PMID:18765415, GO:0008285=PMID:15050747, GO:2000538=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0051279=GO_REF:0000024, GO:0002040=GO_REF:0000024, GO:0007204=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0045638=PMID:15050747, GO:0048041=GO_REF:0000019, GO:0043507=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0043066=PMID:19880522, GO:0005730=GO_REF:0000052, GO:0006915=PMID:10880513, GO:2000058=PMID:19880522, GO:0005524=GO_REF:0000037, GO:0045766=GO_REF:0000019, GO:0009749=GO_REF:0000019, GO:0007165=PMID:7499242, GO:2000060=GO_REF:0000019, GO:0006461=PMID:10867021, GO:0006468=PMID:7529876, GO:0004713=PMID:8939945, GO:0004715=PMID:7544443, GO:0007166=PMID:8849729} Q14289 Protein-tyrosine kinase 2-beta protein 20121127 {GO:0005515=IPI, GO:0030307=IEA, GO:0071300=IMP, GO:0045453=ISS, GO:0043267=IDA, GO:0046330=IMP, GO:0050731=IDA, GO:0030155=IMP, GO:0046777=TAS, GO:0000165=IEA, GO:0045860=IMP, GO:0050848=IEA, GO:0006950=TAS, GO:0018108=IDA, GO:0032863=IEA, GO:0030502=ISS, GO:0010595=IDA, GO:0051000=IEA, GO:0002315=ISS, GO:0032960=ISS, GO:0030424=IEA, GO:0048471=IDA, GO:0042976=IMP, GO:0045471=IEA, GO:0043149=IEA, GO:0005634=IDA, GO:0030426=IEA, GO:0014009=IEA, GO:0005829=TAS, GO:0004871=IEA, GO:0009725=IEA, GO:0048010=IMP, GO:0042493=IEA, GO:2000114=ISS, GO:0045727=IEA, GO:0006970=IEA, GO:0043423=IEA, GO:0009612=IEA, GO:0010226=IEA, GO:0030826=IEA, GO:0042542=IEA, GO:0008360=IMP, GO:0001556=IEA, GO:0042220=IEA, GO:0032403=IEA, GO:0051591=IEA, GO:0031175=IEA, GO:2000249=ISS, GO:0007172=IEA, GO:0043552=ISS, GO:0007173=IEA, GO:0030838=IMP, GO:0070374=IMP, GO:0005856=IEA, GO:0005938=IEA, GO:0070098=ISS, GO:0030335=IMP, GO:0014069=IEA, GO:0030027=IDA, GO:0033209=IMP, GO:0010752=IEA, GO:0051592=IEA, GO:0043534=IEA, GO:0007229=IMP, GO:0010976=IMP, GO:0045121=IEA, GO:0010758=ISS, GO:0005925=IDA, GO:2000379=IEA, GO:0001954=IMP, GO:0045428=IEA, GO:0008284=IMP, GO:0008285=IMP, GO:2000538=ISS, GO:0005886=IEA, GO:0051279=ISS, GO:0002040=ISS, GO:0007204=IEA, GO:0005737=IDA, GO:0045638=IMP, GO:0048041=IEA, GO:0043507=IEA, GO:0001666=IEA, GO:0043066=IMP, GO:0005730=IDA, GO:0006915=TAS, GO:2000058=IDA, GO:0005524=IEA, GO:0045766=IEA, GO:0009749=IEA, GO:0007165=TAS, GO:2000060=IEA, GO:0006461=TAS, GO:0006468=TAS, GO:0004713=TAS, GO:0004715=IDA, GO:0007166=IMP} MAPK cascade, activation of Janus kinase activity, activation of Rac GTPase activity, apoptotic process, blood vessel endothelial cell migration, bone resorption, cell surface receptor signaling pathway, cellular response to retinoic acid, chemokine-mediated signaling pathway, elevation of cytosolic calcium ion concentration, epidermal growth factor receptor signaling pathway, focal adhesion assembly, glial cell proliferation, integrin-mediated signaling pathway, marginal zone B cell differentiation, negative regulation of apoptotic process, negative regulation of bone mineralization, negative regulation of cell proliferation, negative regulation of myeloid cell differentiation, negative regulation of potassium ion transport, neuron projection development, oocyte maturation, peptidyl-tyrosine phosphorylation, positive regulation of B cell chemotaxis, positive regulation of ERK1 and ERK2 cascade, positive regulation of JNK cascade, positive regulation of JUN kinase activity, positive regulation of actin filament polymerization, positive regulation of angiogenesis, positive regulation of cell growth, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of cell-matrix adhesion, positive regulation of endothelial cell migration, positive regulation of neuron projection development, positive regulation of nitric-oxide synthase activity, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of phosphatidylinositol 3-kinase activity, positive regulation of protein kinase activity, positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process, positive regulation of reactive oxygen species metabolic process, positive regulation of translation, protein autophosphorylation, protein complex assembly, protein phosphorylation, regulation of actin cytoskeleton reorganization, regulation of cGMP biosynthetic process, regulation of cGMP-mediated signaling, regulation of calcium-mediated signaling, regulation of cell adhesion, regulation of cell shape, regulation of establishment of cell polarity, regulation of inositol trisphosphate biosynthetic process, regulation of macrophage chemotaxis, regulation of nitric oxide biosynthetic process, regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process, regulation of release of sequestered calcium ion into cytosol, response to cAMP, response to calcium ion, response to cocaine, response to drug, response to ethanol, response to glucose stimulus, response to hormone stimulus, response to hydrogen peroxide, response to hypoxia, response to lithium ion, response to mechanical stimulus, response to osmotic stress, response to stress, signal complex assembly, signal transduction, sprouting angiogenesis, stress fiber assembly, tumor necrosis factor-mediated signaling pathway, vascular endothelial growth factor receptor signaling pathway axon, cell cortex, cytoplasm, cytoskeleton, cytosol, focal adhesion, growth cone, lamellipodium, membrane raft, nucleolus, nucleus, perinuclear region of cytoplasm, plasma membrane, postsynaptic density 3-phosphoinositide-dependent protein kinase binding, ATP binding, non-membrane spanning protein tyrosine kinase activity, protein binding, protein complex binding, protein tyrosine kinase activity, signal transducer activity Human PTK6 HPA UniProtKB {GO:0042506=PMID:17997837, GO:0005515=PMID:16568091, GO:0042503=PMID:16568091, GO:0005886=GO_REF:0000052, GO:0071300=PMID:17910947, GO:0061099=PMID:15539407, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037, GO:0001726=PMID:15572663, GO:0060575=GO_REF:0000019, GO:0005737=PMID:15572663, GO:0046777=PMID:12121988, GO:0016477=PMID:15572663, GO:0004674=GO_REF:0000019, GO:0010976=PMID:17910947, GO:0006468=PMID:8036022, GO:0004715=PMID:10913193, GO:0045926=GO_REF:0000019} Q13882 Protein-tyrosine kinase 6 protein 20110516 {GO:0042506=IDA, GO:0005515=IPI, GO:0042503=IDA, GO:0005886=IDA, GO:0071300=IMP, GO:0061099=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0005524=IEA, GO:0001726=IDA, GO:0060575=IEA, GO:0005737=IDA, GO:0046777=IMP, GO:0016477=IDA, GO:0004674=IEA, GO:0010976=IMP, GO:0006468=TAS, GO:0004715=IDA, GO:0045926=IEA} cell migration, cellular response to retinoic acid, intestinal epithelial cell differentiation, negative regulation of growth, negative regulation of protein tyrosine kinase activity, positive regulation of neuron projection development, protein autophosphorylation, protein phosphorylation, tyrosine phosphorylation of Stat3 protein, tyrosine phosphorylation of Stat5 protein cytoplasm, nucleolus, nucleus, plasma membrane, ruffle ATP binding, non-membrane spanning protein tyrosine kinase activity, protein binding, protein serine/threonine kinase activity Human PTK7 BHF-UCL UniProtKB {GO:0005515=PMID:21132015, GO:0001736=GO_REF:0000019, GO:0031532=PMID:20837484, GO:0071300=PMID:17910947, GO:0003401=GO_REF:0000019, GO:0090179=GO_REF:0000019, GO:0001843=GO_REF:0000019, GO:0005524=GO_REF:0000002, GO:0045198=GO_REF:0000019, GO:0007165=PMID:7478540, GO:0060026=GO_REF:0000019, GO:0016477=PMID:20837484, GO:0016020=GO_REF:0000019, GO:0005887=PMID:7478540, GO:0005911=PMID:20837484, GO:0010976=PMID:17910947, GO:0042060=GO_REF:0000019, GO:0090103=GO_REF:0000019, GO:0060484=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0004713=GO_REF:0000002, GO:0004714=PMID:8882711, GO:0007155=GO_REF:0000037, GO:0060070=PMID:21132015} Q13308 Inactive tyrosine-protein kinase 7 protein 20110707 {GO:0005515=IPI, GO:0001736=IEA, GO:0031532=IMP, GO:0071300=IMP, GO:0003401=IEA, GO:0090179=IEA, GO:0001843=IEA, GO:0005524=IEA, GO:0045198=IEA, GO:0007165=TAS, GO:0060026=IEA, GO:0016477=IMP, GO:0016020=IEA, GO:0005887=TAS, GO:0005911=IDA, GO:0010976=IMP, GO:0042060=IEA, GO:0090103=IEA, GO:0060484=IEA, GO:0016021=IEA, GO:0004713=IEA, GO:0004714=TAS, GO:0007155=IEA, GO:0060070=IMP} actin cytoskeleton reorganization, axis elongation, canonical Wnt receptor signaling pathway, cell adhesion, cell migration, cellular response to retinoic acid, cochlea morphogenesis, convergent extension, establishment of epithelial cell apical/basal polarity, establishment of planar polarity, lung-associated mesenchyme development, neural tube closure, planar cell polarity pathway involved in neural tube closure, positive regulation of neuron projection development, signal transduction, wound healing cell-cell junction, integral to membrane, integral to plasma membrane, membrane ATP binding, protein binding, protein tyrosine kinase activity, transmembrane receptor protein tyrosine kinase activity Human PTMA HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006351=PMID:10854063} P06454 Prothymosin alpha protein 20120912 {GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0006351=TAS} transcription, DNA-dependent cytoplasm, nucleolus, nucleus Human PTMS PINC UniProtKB {GO:0006260=PMID:10854063, GO:0005634=PMID:10854063} P20962 Parathymosin protein 20030904 {GO:0006260=TAS, GO:0005634=TAS} DNA replication nucleus Human PTN LIFEdb UniProtKB {GO:0008284=PMID:2270483, GO:0005783=GO_REF:0000054, GO:0004864=PMID:10706604, GO:0007185=PMID:10706604, GO:0051781=GO_REF:0000037, GO:0030282=GO_REF:0000019, GO:0007612=GO_REF:0000019, GO:0005615=PMID:10706604, GO:0008201=GO_REF:0000037, GO:0008083=GO_REF:0000037, GO:0007399=PMID:2270483} P21246 Pleiotrophin protein 20100607 {GO:0008284=TAS, GO:0005783=IDA, GO:0004864=TAS, GO:0007185=TAS, GO:0051781=IEA, GO:0030282=IEA, GO:0007612=IEA, GO:0005615=TAS, GO:0008201=IEA, GO:0008083=IEA, GO:0007399=TAS} bone mineralization, learning, nervous system development, positive regulation of cell division, positive regulation of cell proliferation, transmembrane receptor protein tyrosine phosphatase signaling pathway endoplasmic reticulum, extracellular space growth factor activity, heparin binding, protein phosphatase inhibitor activity Human PTOV1 UniProtKB UniProtKB {GO:0048471=GO_REF:0000039, GO:0006355=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q86YD1 Prostate tumor-overexpressed gene 1 protein protein 20130413 {GO:0048471=IEA, GO:0006355=IEA, GO:0005886=IEA, GO:0005634=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus, perinuclear region of cytoplasm, plasma membrane Human UniProtKB-SubCell:SL-0198 PTP4A1 GOC UniProtKB {GO:0016791=GO_REF:0000002, GO:0005737=PMID:10940933, GO:0007049=GO_REF:0000037, GO:0030335=GO_REF:0000019, GO:0005783=GO_REF:0000039, GO:0005819=GO_REF:0000039, GO:0009898=PMID:10940933, GO:0007275=GO_REF:0000037, GO:0035335=PMID:10569806, GO:0004725=PMID:10569806, GO:0005769=GO_REF:0000039} Q93096 Protein tyrosine phosphatase type IVA 1 protein 20130413 {GO:0016791=IEA, GO:0005737=IDA, GO:0007049=IEA, GO:0030335=IEA, GO:0005783=IEA, GO:0005819=IEA, GO:0009898=IDA, GO:0007275=IEA, GO:0035335=NAS, GO:0004725=NAS, GO:0005769=IEA} cell cycle, multicellular organismal development, peptidyl-tyrosine dephosphorylation, positive regulation of cell migration cytoplasm, early endosome, endoplasmic reticulum, internal side of plasma membrane, spindle phosphatase activity, protein tyrosine phosphatase activity Human PTP4A2 PINC UniProtKB {GO:0005737=PMID:10940933, GO:0005886=GO_REF:0000039, GO:0004727=PMID:9514946, GO:0005769=GO_REF:0000039} Q12974 Protein tyrosine phosphatase type IVA 2 protein 20030904 {GO:0005737=IDA, GO:0005886=IEA, GO:0004727=TAS, GO:0005769=IEA} cytoplasm, early endosome, plasma membrane prenylated protein tyrosine phosphatase activity Human PTP4A3 PINC UniProtKB {GO:0005886=GO_REF:0000039, GO:0004727=PMID:9514946, GO:0005769=GO_REF:0000039} O75365 Protein tyrosine phosphatase type IVA 3 protein 20030904 {GO:0005886=IEA, GO:0004727=TAS, GO:0005769=IEA} early endosome, plasma membrane prenylated protein tyrosine phosphatase activity Human PTPLAD1 GOC UniProtKB {GO:0007264=PMID:10747961, GO:0007249=GO_REF:0000019, GO:0007254=GO_REF:0000019, GO:0007266=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0007257=PMID:10747961, GO:0016829=GO_REF:0000037, GO:0043547=PMID:10747961, GO:0016601=PMID:10747961, GO:0005789=GO_REF:0000039, GO:0006633=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005096=PMID:10747961} Q9P035 "Very-long-chain (3R)-3-hydroxyacyl-""acyl-carrier protein"" dehydratase 3" protein 20130413 {GO:0007264=TAS, GO:0007249=IEA, GO:0007254=IEA, GO:0007266=IEA, GO:0005575=ND, GO:0007257=TAS, GO:0016829=IEA, GO:0043547=TAS, GO:0016601=NAS, GO:0005789=IEA, GO:0006633=IEA, GO:0016021=IEA, GO:0005096=TAS} I-kappaB kinase/NF-kappaB cascade, JNK cascade, Rac protein signal transduction, Rho protein signal transduction, activation of JUN kinase activity, fatty acid biosynthetic process, positive regulation of GTPase activity, small GTPase mediated signal transduction cellular_component, endoplasmic reticulum membrane, integral to membrane GTPase activator activity, lyase activity Human PTPLB UniProtKB UniProtKB {GO:0005789=GO_REF:0000039, GO:0006633=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0016829=GO_REF:0000037} Q6Y1H2 "Very-long-chain (3R)-3-hydroxyacyl-""acyl-carrier protein"" dehydratase 2" protein 20130413 {GO:0005789=IEA, GO:0006633=IEA, GO:0016021=IEA, GO:0016829=IEA} fatty acid biosynthetic process endoplasmic reticulum membrane, integral to membrane lyase activity Human UniProtKB-SubCell:SL-0097 PTPMT1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000033, GO:0004439=GO_REF:0000033, GO:0006470=GO_REF:0000033, GO:0046855=GO_REF:0000033, GO:0008962=GO_REF:0000024, GO:0005743=GO_REF:0000039, GO:0032049=GO_REF:0000024, GO:0008138=GO_REF:0000033, GO:0004725=GO_REF:0000003} Q8WUK0 Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 protein 20120806 {GO:0005739=IBA, GO:0004439=IBA, GO:0006470=IBA, GO:0046855=IBA, GO:0008962=ISS, GO:0005743=IEA, GO:0032049=ISS, GO:0008138=IBA, GO:0004725=IEA} cardiolipin biosynthetic process, inositol phosphate dephosphorylation, protein dephosphorylation mitochondrial inner membrane, mitochondrion phosphatidylglycerophosphatase activity, phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human UniProtKB:Q66GT5 PTPN1 HPA UniProtKB {GO:0005515=PMID:17159996, GO:0008286=GO_REF:0000019, GO:0005886=PMID:21135139, GO:0005783=GO_REF:0000052, GO:0005158=GO_REF:0000019, GO:0019221=Reactome:REACT_25229, GO:0060397=Reactome:REACT_111133, GO:0035335=PMID:21135139, GO:0030968=PMID:22169477, GO:0005829=Reactome:REACT_111219, GO:0060334=Reactome:REACT_24980, GO:0060337=Reactome:REACT_25162, GO:0060338=Reactome:REACT_25216, GO:0030100=PMID:21135139, GO:0004725=Reactome:REACT_111061, GO:0060333=Reactome:REACT_25078, GO:0031532=PMID:21135139, GO:0019901=PMID:22169477, GO:0046627=PMID:11742412, GO:0046626=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0031410=GO_REF:0000019, GO:0009966=PMID:21135139, GO:0046875=PMID:21135139, GO:0007596=Reactome:REACT_604, GO:0005789=GO_REF:0000039, GO:0008270=PMID:18074158, GO:0019899=PMID:22169477, GO:0005769=PMID:21135139} P18031 Tyrosine-protein phosphatase non-receptor type 1 protein 20081203 {GO:0005515=IPI, GO:0008286=IEA, GO:0005886=IDA, GO:0005783=IDA, GO:0005158=IEA, GO:0019221=TAS, GO:0060397=TAS, GO:0035335=IDA, GO:0030968=IDA, GO:0005829=TAS, GO:0060334=TAS, GO:0060337=TAS, GO:0060338=TAS, GO:0030100=IDA, GO:0004725=TAS, GO:0060333=TAS, GO:0031532=IMP, GO:0019901=IPI, GO:0046627=NAS, GO:0046626=IEA, GO:0030168=TAS, GO:0031410=IEA, GO:0009966=IMP, GO:0046875=IPI, GO:0007596=TAS, GO:0005789=IEA, GO:0008270=IDA, GO:0019899=IPI, GO:0005769=IDA} JAK-STAT cascade involved in growth hormone signaling pathway, actin cytoskeleton reorganization, blood coagulation, cytokine-mediated signaling pathway, endoplasmic reticulum unfolded protein response, insulin receptor signaling pathway, interferon-gamma-mediated signaling pathway, negative regulation of insulin receptor signaling pathway, peptidyl-tyrosine dephosphorylation, platelet activation, regulation of endocytosis, regulation of insulin receptor signaling pathway, regulation of interferon-gamma-mediated signaling pathway, regulation of signal transduction, regulation of type I interferon-mediated signaling pathway, type I interferon-mediated signaling pathway cytoplasmic vesicle, cytosol, early endosome, endoplasmic reticulum, endoplasmic reticulum membrane, plasma membrane enzyme binding, ephrin receptor binding, insulin receptor binding, protein binding, protein kinase binding, protein tyrosine phosphatase activity, zinc ion binding Human PTPN11 BHF-UCL UniProtKB {GO:0005515=PMID:21706016, GO:0005158=PMID:7493946, GO:0019221=Reactome:REACT_25229, GO:0043560=GO_REF:0000019, GO:0050900=Reactome:REACT_12051, GO:0035335=PMID:10655584, GO:0007507=PMID:12058348, GO:0060334=Reactome:REACT_24980, GO:0048609=GO_REF:0000019, GO:0060337=Reactome:REACT_25162, GO:0007173=Reactome:REACT_9417, GO:0060338=Reactome:REACT_25216, GO:0043274=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0046887=GO_REF:0000019, GO:0048806=PMID:12058348, GO:0046676=GO_REF:0000019, GO:0060333=Reactome:REACT_25078, GO:0038127=PMID:15133037, GO:0048839=PMID:12058348, GO:0019904=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0007420=PMID:11704759, GO:0005070=PMID:7493946, GO:0045087=Reactome:REACT_6802, GO:0006641=GO_REF:0000019, GO:0042445=GO_REF:0000019, GO:0000077=GO_REF:0000019, GO:0008286=Reactome:REACT_498, GO:0033628=PMID:10655584, GO:0031295=Reactome:REACT_19344, GO:0051428=GO_REF:0000019, GO:0060125=GO_REF:0000019, GO:0005829=Reactome:REACT_147854, GO:0005739=GO_REF:0000019, GO:0000187=GO_REF:0000019, GO:0005737=PMID:10940933, GO:0035265=GO_REF:0000019, GO:0040014=GO_REF:0000019, GO:0051463=GO_REF:0000019, GO:0004721=PMID:15133037, GO:0004725=Reactome:REACT_23816, GO:0046825=GO_REF:0000019, GO:0004726=Reactome:REACT_12629, GO:0030971=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0048013=PMID:10655584, GO:0048015=Reactome:REACT_12464, GO:0042593=GO_REF:0000019, GO:0036302=PMID:12058348, GO:2001275=PMID:7493946, GO:0009755=GO_REF:0000019, GO:0060325=PMID:11704759, GO:0007596=Reactome:REACT_604} Q06124 Tyrosine-protein phosphatase non-receptor type 11 protein 20120815 {GO:0005515=IPI, GO:0005158=IPI, GO:0019221=TAS, GO:0043560=IEA, GO:0050900=TAS, GO:0035335=IMP, GO:0007507=IMP, GO:0060334=TAS, GO:0048609=IEA, GO:0060337=TAS, GO:0007173=TAS, GO:0060338=TAS, GO:0043274=IEA, GO:0007411=TAS, GO:0046887=IEA, GO:0048806=IMP, GO:0046676=IEA, GO:0060333=TAS, GO:0038127=IDA, GO:0048839=IMP, GO:0019904=IEA, GO:0043234=IEA, GO:0008543=TAS, GO:0007420=IMP, GO:0005070=IDA, GO:0045087=TAS, GO:0006641=IEA, GO:0042445=IEA, GO:0000077=IEA, GO:0008286=TAS, GO:0033628=IMP, GO:0031295=TAS, GO:0051428=IEA, GO:0060125=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0000187=IEA, GO:0005737=IDA, GO:0035265=IEA, GO:0040014=IEA, GO:0051463=IEA, GO:0004721=IDA, GO:0004725=TAS, GO:0046825=IEA, GO:0004726=TAS, GO:0030971=IEA, GO:0048011=TAS, GO:0048013=IDA, GO:0048015=TAS, GO:0042593=IEA, GO:0036302=IMP, GO:2001275=IDA, GO:0009755=IEA, GO:0060325=IMP, GO:0007596=TAS} DNA damage checkpoint, ERBB signaling pathway, T cell costimulation, activation of MAPK activity, atrioventricular canal development, axon guidance, blood coagulation, brain development, cytokine-mediated signaling pathway, ephrin receptor signaling pathway, epidermal growth factor receptor signaling pathway, face morphogenesis, fibroblast growth factor receptor signaling pathway, genitalia development, glucose homeostasis, heart development, hormone metabolic process, hormone-mediated signaling pathway, innate immune response, inner ear development, insulin receptor signaling pathway, interferon-gamma-mediated signaling pathway, leukocyte migration, multicellular organismal reproductive process, negative regulation of cortisol secretion, negative regulation of growth hormone secretion, negative regulation of insulin secretion, neurotrophin TRK receptor signaling pathway, organ growth, peptidyl-tyrosine dephosphorylation, phosphatidylinositol-mediated signaling, positive regulation of glucose import in response to insulin stimulus, positive regulation of hormone secretion, regulation of cell adhesion mediated by integrin, regulation of interferon-gamma-mediated signaling pathway, regulation of multicellular organism growth, regulation of protein export from nucleus, regulation of type I interferon-mediated signaling pathway, triglyceride metabolic process, type I interferon-mediated signaling pathway cytoplasm, cytosol, mitochondrion, protein complex SH3/SH2 adaptor activity, insulin receptor binding, insulin receptor substrate binding, non-membrane spanning protein tyrosine phosphatase activity, peptide hormone receptor binding, phospholipase binding, phosphoprotein phosphatase activity, protein binding, protein domain specific binding, protein tyrosine phosphatase activity, receptor tyrosine kinase binding Human PTPN12 HPA UniProtKB {GO:0005515=PMID:21376233, GO:0017124=PMID:9285683, GO:0005737=GO_REF:0000052, GO:0006470=PMID:8454633, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000052, GO:0002102=GO_REF:0000039, GO:0042995=GO_REF:0000037, GO:0004725=GO_REF:0000002, GO:0004726=PMID:8454633, GO:0005829=GO_REF:0000019} Q05209 Tyrosine-protein phosphatase non-receptor type 12 protein 20111111 {GO:0005515=IPI, GO:0017124=IPI, GO:0005737=IDA, GO:0006470=TAS, GO:0030054=IEA, GO:0005886=IDA, GO:0002102=IEA, GO:0042995=IEA, GO:0004725=IEA, GO:0004726=TAS, GO:0005829=IEA} protein dephosphorylation cell junction, cell projection, cytoplasm, cytosol, plasma membrane, podosome SH3 domain binding, non-membrane spanning protein tyrosine phosphatase activity, protein binding, protein tyrosine phosphatase activity Human PTPN13 GOC UniProtKB {GO:0005515=PMID:17657516, GO:0005737=PMID:14516276, GO:0006470=PMID:7929060, GO:0005886=PMID:14516276, GO:0005634=PMID:11356191, GO:0005856=GO_REF:0000039, GO:0035335=PMID:7536343, GO:0030027=PMID:11356191, GO:0004725=PMID:15611135} Q12923 Tyrosine-protein phosphatase non-receptor type 13 protein 20130413 {GO:0005515=IPI, GO:0005737=IDA, GO:0006470=TAS, GO:0005886=IDA, GO:0005634=IDA, GO:0005856=IEA, GO:0035335=TAS, GO:0030027=IDA, GO:0004725=IDA} peptidyl-tyrosine dephosphorylation, protein dephosphorylation cytoplasm, cytoskeleton, lamellipodium, nucleus, plasma membrane protein binding, protein tyrosine phosphatase activity Human PTPN14 GOC UniProtKB {GO:0005515=PMID:22525271, GO:0003712=PMID:22525271, GO:0030971=PMID:20826270, GO:0006355=GO_REF:0000037, GO:0008285=PMID:22948661, GO:0005634=PMID:22525271, GO:0035335=PMID:7733990, GO:0006351=GO_REF:0000037, GO:0001946=PMID:20826270, GO:0005737=PMID:22525271, GO:0006470=PMID:7733990, GO:0005856=GO_REF:0000039, GO:0004725=PMID:22525271, GO:0046825=PMID:22948661} Q15678 Tyrosine-protein phosphatase non-receptor type 14 protein 20130413 {GO:0005515=IPI, GO:0003712=IMP, GO:0030971=IPI, GO:0006355=IEA, GO:0008285=IMP, GO:0005634=IDA, GO:0035335=TAS, GO:0006351=IEA, GO:0001946=IMP, GO:0005737=IDA, GO:0006470=TAS, GO:0005856=IEA, GO:0004725=IMP, GO:0046825=IDA} lymphangiogenesis, negative regulation of cell proliferation, peptidyl-tyrosine dephosphorylation, protein dephosphorylation, regulation of protein export from nucleus, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, cytoskeleton, nucleus protein binding, protein tyrosine phosphatase activity, receptor tyrosine kinase binding, transcription cofactor activity Human PTPN18 PINC UniProtKB {GO:0005737=GO_REF:0000039, GO:0006470=PMID:8950995, GO:0005634=GO_REF:0000039, GO:0004725=GO_REF:0000002, GO:0004726=GO_REF:0000019} Q99952 Tyrosine-protein phosphatase non-receptor type 18 protein 20030904 {GO:0005737=IEA, GO:0006470=TAS, GO:0005634=IEA, GO:0004725=IEA, GO:0004726=IEA} protein dephosphorylation cytoplasm, nucleus non-membrane spanning protein tyrosine phosphatase activity, protein tyrosine phosphatase activity Human PTPN2 GOC UniProtKB {GO:0005515=PMID:12907755, GO:0060334=Reactome:REACT_24980, GO:0008286=GO_REF:0000019, GO:0006470=PMID:2546150, GO:0005783=PMID:10940933, GO:0019221=Reactome:REACT_25229, GO:0005654=Reactome:REACT_25185, GO:0035335=PMID:2546150, GO:0004725=PMID:2546150, GO:0060333=Reactome:REACT_25078, GO:0004726=GO_REF:0000019} P17706 Tyrosine-protein phosphatase non-receptor type 2 protein 20130413 {GO:0005515=IPI, GO:0060334=TAS, GO:0008286=IEA, GO:0006470=TAS, GO:0005783=IDA, GO:0019221=TAS, GO:0005654=TAS, GO:0035335=TAS, GO:0004725=TAS, GO:0060333=TAS, GO:0004726=IEA} cytokine-mediated signaling pathway, insulin receptor signaling pathway, interferon-gamma-mediated signaling pathway, peptidyl-tyrosine dephosphorylation, protein dephosphorylation, regulation of interferon-gamma-mediated signaling pathway endoplasmic reticulum, nucleoplasm non-membrane spanning protein tyrosine phosphatase activity, protein binding, protein tyrosine phosphatase activity Human PTPN21 GOC UniProtKB {GO:0005737=GO_REF:0000037, GO:0006470=PMID:7519780, GO:0005856=GO_REF:0000039, GO:0035335=PMID:7519780, GO:0004725=GO_REF:0000003} Q16825 Tyrosine-protein phosphatase non-receptor type 21 protein 20130413 {GO:0005737=IEA, GO:0006470=TAS, GO:0005856=IEA, GO:0035335=TAS, GO:0004725=IEA} peptidyl-tyrosine dephosphorylation, protein dephosphorylation cytoplasm, cytoskeleton protein tyrosine phosphatase activity Human PTPN22 GOC UniProtKB {GO:0005515=PMID:10068674, GO:0050852=GO_REF:0000019, GO:0050855=PMID:19265110, GO:0048471=PMID:10068674, GO:0017124=GO_REF:0000024, GO:0050868=PMID:18299186, GO:0005634=PMID:10940933, GO:0035335=PMID:18056643, GO:0032817=PMID:20522204, GO:0050860=PMID:18056643, GO:0005737=PMID:10068674, GO:0006470=PMID:10068674, GO:0030217=GO_REF:0000024, GO:0045088=PMID:20522204, GO:0009898=PMID:10940933, GO:0019900=GO_REF:0000024, GO:0004725=PMID:10068674, GO:0035644=GO_REF:0000024} Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 protein 20130413 {GO:0005515=IPI, GO:0050852=IEA, GO:0050855=NAS, GO:0048471=IDA, GO:0017124=ISS, GO:0050868=IMP, GO:0005634=IDA, GO:0035335=IDA, GO:0032817=IDA, GO:0050860=IDA, GO:0005737=IDA, GO:0006470=IDA, GO:0030217=ISS, GO:0045088=IC, GO:0009898=IDA, GO:0019900=ISS, GO:0004725=IDA, GO:0035644=ISS} T cell differentiation, T cell receptor signaling pathway, negative regulation of T cell activation, negative regulation of T cell receptor signaling pathway, peptidyl-tyrosine dephosphorylation, phosphoanandamide dephosphorylation, protein dephosphorylation, regulation of B cell receptor signaling pathway, regulation of innate immune response, regulation of natural killer cell proliferation cytoplasm, internal side of plasma membrane, nucleus, perinuclear region of cytoplasm SH3 domain binding, kinase binding, protein binding, protein tyrosine phosphatase activity Human PTPN23 UniProtKB UniProtKB {GO:0005515=PMID:21179510, GO:0005929=GO_REF:0000037, GO:0005737=PMID:21179510, GO:0060271=PMID:20393563, GO:0016023=GO_REF:0000039, GO:0005634=PMID:21179510, GO:0005932=PMID:20393563, GO:0004725=GO_REF:0000003, GO:0005768=PMID:21179510} Q9H3S7 Tyrosine-protein phosphatase non-receptor type 23 protein 20110923 {GO:0005515=IPI, GO:0005929=IEA, GO:0005737=IDA, GO:0060271=IMP, GO:0016023=IEA, GO:0005634=IDA, GO:0005932=IDA, GO:0004725=IEA, GO:0005768=IDA} cilium morphogenesis cilium, cytoplasm, cytoplasmic membrane-bounded vesicle, endosome, microtubule basal body, nucleus protein binding, protein tyrosine phosphatase activity Human PTPN3 GOC UniProtKB {GO:0005515=PMID:12207026, GO:0008092=GO_REF:0000002, GO:0005737=PMID:10940933, GO:0006470=PMID:10364224, GO:0051045=PMID:12207026, GO:0045930=PMID:10364224, GO:0051117=PMID:10364224, GO:0009898=PMID:10940933, GO:0001784=PMID:10364224, GO:0005856=GO_REF:0000039, GO:0035335=PMID:19167335, GO:0004725=PMID:19167335} P26045 Tyrosine-protein phosphatase non-receptor type 3 protein 20130413 {GO:0005515=IPI, GO:0008092=IEA, GO:0005737=IDA, GO:0006470=IDA, GO:0051045=IMP, GO:0045930=IDA, GO:0051117=IPI, GO:0009898=IDA, GO:0001784=IPI, GO:0005856=IEA, GO:0035335=IDA, GO:0004725=IDA} negative regulation of membrane protein ectodomain proteolysis, negative regulation of mitotic cell cycle, peptidyl-tyrosine dephosphorylation, protein dephosphorylation cytoplasm, cytoskeleton, internal side of plasma membrane ATPase binding, cytoskeletal protein binding, phosphotyrosine binding, protein binding, protein tyrosine phosphatase activity Human PTPN4 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0008092=GO_REF:0000002, GO:0005737=PMID:10940933, GO:0006470=PMID:1648233, GO:0009898=PMID:10940933, GO:0005856=GO_REF:0000039, GO:0004725=GO_REF:0000002, GO:0019898=GO_REF:0000002, GO:0004726=GO_REF:0000019} P29074 Tyrosine-protein phosphatase non-receptor type 4 protein 20130415 {GO:0005515=IPI, GO:0008092=IEA, GO:0005737=IDA, GO:0006470=TAS, GO:0009898=IDA, GO:0005856=IEA, GO:0004725=IEA, GO:0019898=IEA, GO:0004726=IEA} protein dephosphorylation cytoplasm, cytoskeleton, extrinsic to membrane, internal side of plasma membrane cytoskeletal protein binding, non-membrane spanning protein tyrosine phosphatase activity, protein binding, protein tyrosine phosphatase activity Human UniProtKB:P46108 PTPN5 UniProtKB UniProtKB {GO:0006470=PMID:7490079, GO:0005789=GO_REF:0000039, GO:0001784=PMID:16441242, GO:0016021=PMID:2263249, GO:0004725=PMID:7490079} P54829 Tyrosine-protein phosphatase non-receptor type 5 protein 20100118 {GO:0006470=TAS, GO:0005789=IEA, GO:0001784=IDA, GO:0016021=TAS, GO:0004725=TAS} protein dephosphorylation endoplasmic reticulum membrane, integral to membrane phosphotyrosine binding, protein tyrosine phosphatase activity Human PTPN6 GOC UniProtKB {GO:0050853=GO_REF:0000019, GO:0005515=PMID:19838216, GO:0045577=GO_REF:0000019, GO:0008284=PMID:19749791, GO:0017124=GO_REF:0000019, GO:0008285=PMID:10497187, GO:0008283=PMID:11266449, GO:0042267=GO_REF:0000019, GO:0031295=Reactome:REACT_19344, GO:0019221=Reactome:REACT_25229, GO:0050732=PMID:19749791, GO:0005634=PMID:19838216, GO:0060397=Reactome:REACT_111133, GO:0050900=Reactome:REACT_12051, GO:0035335=Reactome:REACT_23816, GO:2000045=PMID:19838216, GO:0030154=PMID:11266449, GO:0005829=Reactome:REACT_111223, GO:0042130=GO_REF:0000019, GO:0060334=Reactome:REACT_24980, GO:0035556=GO_REF:0000019, GO:0042105=GO_REF:0000019, GO:0005737=PMID:19838216, GO:0060337=Reactome:REACT_25162, GO:0006470=PMID:11266449, GO:0060338=Reactome:REACT_25216, GO:0005001=PMID:11266449, GO:0043407=GO_REF:0000019, GO:0002924=GO_REF:0000019, GO:0070372=PMID:11266449, GO:0042169=GO_REF:0000019, GO:0004725=Reactome:REACT_23816, GO:0060333=Reactome:REACT_25078, GO:0019901=PMID:11266449, GO:0006915=PMID:10506221, GO:0014068=PMID:19838216, GO:0050860=GO_REF:0000019, GO:0016020=PMID:10506221, GO:0007186=PMID:7781604, GO:0007596=Reactome:REACT_604, GO:0001784=GO_REF:0000019} P29350 Tyrosine-protein phosphatase non-receptor type 6 protein 20130413 {GO:0050853=IEA, GO:0005515=IPI, GO:0045577=IEA, GO:0008284=IMP, GO:0017124=IEA, GO:0008285=NAS, GO:0008283=IDA, GO:0042267=IEA, GO:0031295=TAS, GO:0019221=TAS, GO:0050732=IMP, GO:0005634=IDA, GO:0060397=TAS, GO:0050900=TAS, GO:0035335=TAS, GO:2000045=IMP, GO:0030154=IDA, GO:0005829=TAS, GO:0042130=IEA, GO:0060334=TAS, GO:0035556=IEA, GO:0042105=IEA, GO:0005737=IDA, GO:0060337=TAS, GO:0006470=IDA, GO:0060338=TAS, GO:0005001=IDA, GO:0043407=IEA, GO:0002924=IEA, GO:0070372=IDA, GO:0042169=IEA, GO:0004725=TAS, GO:0060333=TAS, GO:0019901=IPI, GO:0006915=TAS, GO:0014068=IMP, GO:0050860=IEA, GO:0016020=TAS, GO:0007186=TAS, GO:0007596=TAS, GO:0001784=IEA} B cell receptor signaling pathway, G-protein coupled receptor signaling pathway, JAK-STAT cascade involved in growth hormone signaling pathway, T cell costimulation, apoptotic process, blood coagulation, cell differentiation, cell proliferation, cytokine-mediated signaling pathway, interferon-gamma-mediated signaling pathway, intracellular signal transduction, leukocyte migration, natural killer cell mediated cytotoxicity, negative regulation of MAP kinase activity, negative regulation of T cell proliferation, negative regulation of T cell receptor signaling pathway, negative regulation of cell proliferation, negative regulation of humoral immune response mediated by circulating immunoglobulin, negative regulation of peptidyl-tyrosine phosphorylation, peptidyl-tyrosine dephosphorylation, positive regulation of cell proliferation, positive regulation of phosphatidylinositol 3-kinase cascade, protein dephosphorylation, regulation of B cell differentiation, regulation of ERK1 and ERK2 cascade, regulation of G1/S transition of mitotic cell cycle, regulation of interferon-gamma-mediated signaling pathway, regulation of type I interferon-mediated signaling pathway, type I interferon-mediated signaling pathway alpha-beta T cell receptor complex, cytoplasm, cytosol, membrane, nucleus SH2 domain binding, SH3 domain binding, phosphotyrosine binding, protein binding, protein kinase binding, protein tyrosine phosphatase activity, transmembrane receptor protein tyrosine phosphatase activity Human PTPN7 ENSEMBL UniProtKB {GO:0005737=PMID:10940933, GO:0006470=PMID:1530918, GO:0009898=PMID:10940933, GO:0005856=GO_REF:0000039, GO:0035335=PMID:1530918, GO:0004725=GO_REF:0000002, GO:0005829=GO_REF:0000019} Q5SXQ0 Tyrosine-protein phosphatase non-receptor type 7 protein 20130413 {GO:0005737=IDA, GO:0006470=TAS, GO:0009898=IDA, GO:0005856=IEA, GO:0035335=TAS, GO:0004725=IEA, GO:0005829=IEA} peptidyl-tyrosine dephosphorylation, protein dephosphorylation cytoplasm, cytoskeleton, cytosol, internal side of plasma membrane protein tyrosine phosphatase activity Human Ensembl:ENSRNOP00000007833 PTPN9 GOC UniProtKB {GO:0005515=PMID:12907755, GO:0044444=PMID:10940933, GO:0006470=PMID:1557404, GO:0035335=PMID:19167335, GO:0004725=PMID:19167335, GO:0004726=PMID:1557404} P43378 Tyrosine-protein phosphatase non-receptor type 9 protein 20130413 {GO:0005515=IPI, GO:0044444=IDA, GO:0006470=TAS, GO:0035335=IDA, GO:0004725=IDA, GO:0004726=TAS} peptidyl-tyrosine dephosphorylation, protein dephosphorylation cytoplasmic part non-membrane spanning protein tyrosine phosphatase activity, protein binding, protein tyrosine phosphatase activity Human PTPRA ENSEMBL UniProtKB {GO:0008286=GO_REF:0000019, GO:0005886=Reactome:REACT_18375, GO:0007411=Reactome:REACT_18266, GO:0005001=PMID:2169617, GO:0005887=PMID:2169617, GO:0006468=GO_REF:0000019, GO:0035335=PMID:10748206, GO:0004725=PMID:10748206} Q5JWG3 Receptor-type tyrosine-protein phosphatase alpha protein 20130413 {GO:0008286=IEA, GO:0005886=TAS, GO:0007411=TAS, GO:0005001=TAS, GO:0005887=TAS, GO:0006468=IEA, GO:0035335=TAS, GO:0004725=TAS} axon guidance, insulin receptor signaling pathway, peptidyl-tyrosine dephosphorylation, protein phosphorylation integral to plasma membrane, plasma membrane protein tyrosine phosphatase activity, transmembrane receptor protein tyrosine phosphatase activity Human Ensembl:ENSMUSP00000076533 PTPRB IntAct UniProtKB {GO:0005515=PMID:19167335, GO:0006470=PMID:2170109, GO:0005887=PMID:2170109, GO:0005001=PMID:2170109, GO:0016311=PMID:19116766, GO:0006796=PMID:2170109, GO:0001525=GO_REF:0000019, GO:0004725=GO_REF:0000002} P23467 Receptor-type tyrosine-protein phosphatase beta protein 20130415 {GO:0005515=IPI, GO:0006470=TAS, GO:0005887=TAS, GO:0005001=TAS, GO:0016311=IDA, GO:0006796=TAS, GO:0001525=IEA, GO:0004725=IEA} angiogenesis, dephosphorylation, phosphate-containing compound metabolic process, protein dephosphorylation integral to plasma membrane protein binding, protein tyrosine phosphatase activity, transmembrane receptor protein tyrosine phosphatase activity Human UniProtKB:Q02763 PTPRC GOC UniProtKB {GO:0005515=PMID:19167335, GO:0033261=PMID:1793833, GO:0050732=GO_REF:0000019, GO:0048539=PMID:21911094, GO:0035335=PMID:2853967, GO:0051607=GO_REF:0000024, GO:0007411=Reactome:REACT_18266, GO:0005001=PMID:2845400, GO:0006933=PMID:21911094, GO:0045860=PMID:15275963, GO:0046641=GO_REF:0000019, GO:0034113=GO_REF:0000019, GO:0010332=GO_REF:0000019, GO:0051209=GO_REF:0000024, GO:0019901=PMID:14625311, GO:0045588=GO_REF:0000019, GO:0043395=GO_REF:0000019, GO:0005887=GO_REF:0000024, GO:0016311=GO_REF:0000024, GO:0045121=GO_REF:0000039, GO:0005925=GO_REF:0000024, GO:0048304=GO_REF:0000019, GO:0009897=PMID:17213291, GO:0050853=GO_REF:0000024, GO:0045577=GO_REF:0000019, GO:0050852=Reactome:REACT_12526, GO:0050855=GO_REF:0000019, GO:0005886=Reactome:REACT_19295, GO:0050857=GO_REF:0000024, GO:0030890=PMID:1793833, GO:0048864=PMID:21911094, GO:0002378=PMID:1793833, GO:0031953=GO_REF:0000019, GO:0000187=GO_REF:0000019, GO:0002925=GO_REF:0000019, GO:0006470=GO_REF:0000024, GO:0042098=GO_REF:0000019, GO:0001960=GO_REF:0000024, GO:0042100=GO_REF:0000024, GO:0002244=PMID:21911094, GO:0030183=GO_REF:0000019, GO:0042102=GO_REF:0000024, GO:0007159=GO_REF:0000019, GO:0051726=GO_REF:0000024, GO:0008201=GO_REF:0000019, GO:0004725=PMID:2853967, GO:0043065=GO_REF:0000019, GO:2000648=PMID:21911094, GO:0045059=GO_REF:0000019, GO:0030217=GO_REF:0000024, GO:0001916=GO_REF:0000019, GO:0001915=GO_REF:0000024, GO:0045060=GO_REF:0000019, GO:0006469=GO_REF:0000024, GO:0007166=PMID:2845400} P08575 Receptor-type tyrosine-protein phosphatase C protein 20130413 {GO:0005515=IPI, GO:0033261=IMP, GO:0050732=IEA, GO:0048539=IMP, GO:0035335=IDA, GO:0051607=ISS, GO:0007411=TAS, GO:0005001=TAS, GO:0006933=IMP, GO:0045860=NAS, GO:0046641=IEA, GO:0034113=IEA, GO:0010332=IEA, GO:0051209=ISS, GO:0019901=IPI, GO:0045588=IEA, GO:0043395=IEA, GO:0005887=ISS, GO:0016311=ISS, GO:0045121=IEA, GO:0005925=ISS, GO:0048304=IEA, GO:0009897=IDA, GO:0050853=ISS, GO:0045577=IEA, GO:0050852=TAS, GO:0050855=IEA, GO:0005886=TAS, GO:0050857=ISS, GO:0030890=IMP, GO:0048864=IMP, GO:0002378=IMP, GO:0031953=IEA, GO:0000187=IEA, GO:0002925=IEA, GO:0006470=ISS, GO:0042098=IEA, GO:0001960=ISS, GO:0042100=ISS, GO:0002244=IMP, GO:0030183=IEA, GO:0042102=ISS, GO:0007159=IEA, GO:0051726=ISS, GO:0008201=IEA, GO:0004725=IDA, GO:0043065=IEA, GO:2000648=IMP, GO:0045059=IEA, GO:0030217=ISS, GO:0001916=IEA, GO:0001915=ISS, GO:0045060=IEA, GO:0006469=ISS, GO:0007166=TAS} B cell differentiation, B cell proliferation, B cell receptor signaling pathway, T cell differentiation, T cell proliferation, T cell receptor signaling pathway, activation of MAPK activity, axon guidance, bone marrow development, cell surface receptor signaling pathway, defense response to virus, dephosphorylation, hematopoietic progenitor cell differentiation, heterotypic cell-cell adhesion, immunoglobulin biosynthetic process, leukocyte cell-cell adhesion, negative regulation of T cell mediated cytotoxicity, negative regulation of cell adhesion involved in substrate-bound cell migration, negative regulation of cytokine-mediated signaling pathway, negative regulation of peptidyl-tyrosine phosphorylation, negative regulation of protein autophosphorylation, negative regulation of protein kinase activity, negative thymic T cell selection, peptidyl-tyrosine dephosphorylation, positive regulation of B cell proliferation, positive regulation of T cell mediated cytotoxicity, positive regulation of T cell proliferation, positive regulation of alpha-beta T cell proliferation, positive regulation of antigen receptor-mediated signaling pathway, positive regulation of apoptotic process, positive regulation of gamma-delta T cell differentiation, positive regulation of humoral immune response mediated by circulating immunoglobulin, positive regulation of isotype switching to IgG isotypes, positive regulation of protein kinase activity, positive regulation of stem cell proliferation, positive thymic T cell selection, protein dephosphorylation, regulation of B cell differentiation, regulation of B cell receptor signaling pathway, regulation of S phase, regulation of cell cycle, release of sequestered calcium ion into cytosol, response to gamma radiation, stem cell development external side of plasma membrane, focal adhesion, integral to plasma membrane, membrane raft, plasma membrane heparan sulfate proteoglycan binding, heparin binding, protein binding, protein kinase binding, protein tyrosine phosphatase activity, transmembrane receptor protein tyrosine phosphatase activity Human PTPRCAP PINC UniProtKB {GO:0005886=PMID:11390434, GO:0006952=PMID:7961877, GO:0016021=GO_REF:0000037} Q14761 Protein tyrosine phosphatase receptor type C-associated protein protein 20040129 {GO:0005886=IDA, GO:0006952=TAS, GO:0016021=IEA} defense response integral to membrane, plasma membrane Human PTPRD BHF-UCL UniProtKB {GO:0005515=PMID:12570871, GO:0005102=GO_REF:0000024, GO:0006796=PMID:7896816, GO:0006470=PMID:7896816, GO:0097105=GO_REF:0000024, GO:0005001=PMID:7896816, GO:0005887=PMID:7896816, GO:0030182=GO_REF:0000024, GO:0050775=GO_REF:0000024, GO:0007185=PMID:7896816, GO:0050839=GO_REF:0000024, GO:0004725=GO_REF:0000002, GO:0007157=GO_REF:0000024} P23468 Receptor-type tyrosine-protein phosphatase delta protein 20120503 {GO:0005515=IPI, GO:0005102=ISS, GO:0006796=NAS, GO:0006470=TAS, GO:0097105=ISS, GO:0005001=TAS, GO:0005887=TAS, GO:0030182=ISS, GO:0050775=ISS, GO:0007185=TAS, GO:0050839=ISS, GO:0004725=IEA, GO:0007157=ISS} heterophilic cell-cell adhesion, neuron differentiation, phosphate-containing compound metabolic process, positive regulation of dendrite morphogenesis, presynaptic membrane assembly, protein dephosphorylation, transmembrane receptor protein tyrosine phosphatase signaling pathway integral to plasma membrane cell adhesion molecule binding, protein binding, protein tyrosine phosphatase activity, receptor binding, transmembrane receptor protein tyrosine phosphatase activity Human UniProtKB:Q64487 PTPRE ENSEMBL UniProtKB {GO:0005515=PMID:10980613, GO:0005886=GO_REF:0000019, GO:0046627=GO_REF:0000019, GO:0005634=PMID:10980613, GO:0033003=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0006470=PMID:2170109, GO:0005001=PMID:2170109, GO:0007185=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0045111=GO_REF:0000052, GO:0004725=GO_REF:0000019} Q5VWH6 Receptor-type tyrosine-protein phosphatase epsilon protein 20130413 {GO:0005515=IPI, GO:0005886=IEA, GO:0046627=IEA, GO:0005634=IDA, GO:0033003=IEA, GO:0042803=IEA, GO:0005737=IEA, GO:0006470=TAS, GO:0005001=TAS, GO:0007185=IEA, GO:0016021=IEA, GO:0045111=IDA, GO:0004725=IEA} negative regulation of insulin receptor signaling pathway, protein dephosphorylation, regulation of mast cell activation, transmembrane receptor protein tyrosine phosphatase signaling pathway cytoplasm, integral to membrane, intermediate filament cytoskeleton, nucleus, plasma membrane protein binding, protein homodimerization activity, protein tyrosine phosphatase activity, transmembrane receptor protein tyrosine phosphatase activity Human Ensembl:ENSRNOP00000021359 PTPRF GOC UniProtKB {GO:0005001=PMID:8995282, GO:0005887=PMID:2972792, GO:0007185=PMID:8995282, GO:0007155=GO_REF:0000037, GO:0008201=GO_REF:0000037, GO:0035335=PMID:7665159, GO:0004725=PMID:10338209} P10586 Receptor-type tyrosine-protein phosphatase F protein 20130413 {GO:0005001=TAS, GO:0005887=TAS, GO:0007185=TAS, GO:0007155=IEA, GO:0008201=IEA, GO:0035335=TAS, GO:0004725=IDA} cell adhesion, peptidyl-tyrosine dephosphorylation, transmembrane receptor protein tyrosine phosphatase signaling pathway integral to plasma membrane heparin binding, protein tyrosine phosphatase activity, transmembrane receptor protein tyrosine phosphatase activity Human PTPRG GOC UniProtKB {GO:0005887=PMID:8382771, GO:0005001=PMID:8382771, GO:0007169=PMID:8382771, GO:0035335=PMID:19167335, GO:0004725=PMID:19167335, GO:0042802=PMID:19167335} P23470 Receptor-type tyrosine-protein phosphatase gamma protein 20130413 {GO:0005887=TAS, GO:0005001=TAS, GO:0007169=TAS, GO:0035335=IDA, GO:0004725=IDA, GO:0042802=IPI} peptidyl-tyrosine dephosphorylation, transmembrane receptor protein tyrosine kinase signaling pathway integral to plasma membrane identical protein binding, protein tyrosine phosphatase activity, transmembrane receptor protein tyrosine phosphatase activity Human PTPRH HPA UniProtKB {GO:0005515=PMID:12907755, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0006470=PMID:8294459, GO:0005887=PMID:8294459, GO:0005001=PMID:8294459, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0004725=GO_REF:0000002} Q9HD43 Receptor-type tyrosine-protein phosphatase H protein 20111111 {GO:0005515=IPI, GO:0005739=IDA, GO:0005737=IDA, GO:0006470=TAS, GO:0005887=TAS, GO:0005001=TAS, GO:0005730=IDA, GO:0006915=IEA, GO:0005634=IDA, GO:0004725=IEA} apoptotic process, protein dephosphorylation cytoplasm, integral to plasma membrane, mitochondrion, nucleolus, nucleus protein binding, protein tyrosine phosphatase activity, transmembrane receptor protein tyrosine phosphatase activity Human PTPRJ IntAct UniProtKB {GO:0005515=PMID:19167335, GO:0051898=PMID:19922411, GO:0051897=PMID:18936167, GO:0030308=PMID:14709717, GO:0008285=PMID:16682945, GO:0008013=PMID:12370829, GO:0005886=PMID:19836242, GO:0060242=PMID:7937872, GO:0051894=PMID:21091576, GO:0030155=PMID:12370829, GO:2000272=GO_REF:0000019, GO:0035335=PMID:9531590, GO:0007507=GO_REF:0000019, GO:0016791=PMID:19494114, GO:0005911=PMID:19332538, GO:0043407=PMID:19494114, GO:0010572=GO_REF:0000019, GO:0010642=PMID:14709717, GO:0004725=PMID:9531590, GO:0051019=PMID:19494114, GO:0001772=PMID:12913111, GO:0030336=PMID:16682945, GO:0070097=PMID:19332538, GO:0045295=PMID:12370829, GO:0009986=PMID:12913111, GO:0019901=PMID:19332538, GO:0042059=PMID:19836242, GO:0032587=GO_REF:0000039, GO:0005161=PMID:10821867, GO:0050860=PMID:12913111, GO:0045785=PMID:21091576, GO:0050918=PMID:14709717, GO:0005887=PMID:7937872, GO:0007596=GO_REF:0000019, GO:0010759=GO_REF:0000019, GO:0048008=PMID:21091576, GO:0001570=GO_REF:0000019, GO:0043116=PMID:19332538} Q12913 Receptor-type tyrosine-protein phosphatase eta protein 20130415 {GO:0005515=IPI, GO:0051898=IMP, GO:0051897=IMP, GO:0030308=IDA, GO:0008285=IDA, GO:0008013=IPI, GO:0005886=IDA, GO:0060242=NAS, GO:0051894=IMP, GO:0030155=IMP, GO:2000272=IEA, GO:0035335=IDA, GO:0007507=IEA, GO:0016791=IDA, GO:0005911=IDA, GO:0043407=IDA, GO:0010572=IEA, GO:0010642=IDA, GO:0004725=IDA, GO:0051019=IPI, GO:0001772=IDA, GO:0030336=IDA, GO:0070097=IPI, GO:0045295=IPI, GO:0009986=IDA, GO:0019901=IPI, GO:0042059=IMP, GO:0032587=IEA, GO:0005161=IPI, GO:0050860=IDA, GO:0045785=IMP, GO:0050918=IDA, GO:0005887=TAS, GO:0007596=IEA, GO:0010759=IEA, GO:0048008=IMP, GO:0001570=IEA, GO:0043116=IDA} blood coagulation, contact inhibition, heart development, negative regulation of MAP kinase activity, negative regulation of T cell receptor signaling pathway, negative regulation of cell growth, negative regulation of cell migration, negative regulation of cell proliferation, negative regulation of epidermal growth factor receptor signaling pathway, negative regulation of platelet-derived growth factor receptor signaling pathway, negative regulation of protein kinase B signaling cascade, negative regulation of receptor activity, negative regulation of vascular permeability, peptidyl-tyrosine dephosphorylation, platelet-derived growth factor receptor signaling pathway, positive chemotaxis, positive regulation of cell adhesion, positive regulation of focal adhesion assembly, positive regulation of macrophage chemotaxis, positive regulation of platelet activation, positive regulation of protein kinase B signaling cascade, regulation of cell adhesion, vasculogenesis cell surface, cell-cell junction, immunological synapse, integral to plasma membrane, plasma membrane, ruffle membrane beta-catenin binding, delta-catenin binding, gamma-catenin binding, mitogen-activated protein kinase binding, phosphatase activity, platelet-derived growth factor receptor binding, protein binding, protein kinase binding, protein tyrosine phosphatase activity Human UniProtKB:Q02763 PTPRK InterPro UniProtKB {GO:0010839=PMID:16263724, GO:0005515=PMID:19167335, GO:0030424=GO_REF:0000019, GO:0008285=PMID:18276111, GO:0008013=PMID:8663237, GO:0035335=PMID:8663237, GO:0030425=GO_REF:0000019, GO:0034644=PMID:16849327, GO:0006470=PMID:16263724, GO:0005912=GO_REF:0000039, GO:0005911=PMID:8663237, GO:0005001=PMID:9047348, GO:0048041=PMID:15899872, GO:0043025=GO_REF:0000019, GO:0007179=PMID:15899872, GO:0007155=PMID:15899872, GO:0004725=GO_REF:0000002, GO:0030336=PMID:18276111, GO:0031256=PMID:15899872, GO:0009986=PMID:18276111, GO:0019901=PMID:15899872, GO:0045295=PMID:8663237, GO:0045786=PMID:15899872, GO:0007165=PMID:16849327, GO:0016477=PMID:15899872, GO:0016020=GO_REF:0000002, GO:0005887=PMID:9047348, GO:0034394=PMID:18276111, GO:0034614=PMID:16849327, GO:0016021=PMID:9047348, GO:0045892=PMID:18276111, GO:0001750=GO_REF:0000019} Q5TG12 Receptor-type tyrosine-protein phosphatase kappa protein 20130413 {GO:0010839=IDA, GO:0005515=IPI, GO:0030424=IEA, GO:0008285=IDA, GO:0008013=IPI, GO:0035335=IDA, GO:0030425=IEA, GO:0034644=IDA, GO:0006470=IDA, GO:0005912=IEA, GO:0005911=IDA, GO:0005001=NAS, GO:0048041=IMP, GO:0043025=IEA, GO:0007179=IDA, GO:0007155=IMP, GO:0004725=IEA, GO:0030336=IDA, GO:0031256=IDA, GO:0009986=IDA, GO:0019901=IPI, GO:0045295=IPI, GO:0045786=IDA, GO:0007165=IDA, GO:0016477=IMP, GO:0016020=IEA, GO:0005887=NAS, GO:0034394=IDA, GO:0034614=IDA, GO:0016021=NAS, GO:0045892=IDA, GO:0001750=IEA} cell adhesion, cell migration, cellular response to UV, cellular response to reactive oxygen species, focal adhesion assembly, negative regulation of cell cycle, negative regulation of cell migration, negative regulation of cell proliferation, negative regulation of keratinocyte proliferation, negative regulation of transcription, DNA-dependent, peptidyl-tyrosine dephosphorylation, protein dephosphorylation, protein localization to cell surface, signal transduction, transforming growth factor beta receptor signaling pathway adherens junction, axon, cell surface, cell-cell junction, dendrite, integral to membrane, integral to plasma membrane, leading edge membrane, membrane, neuronal cell body, photoreceptor outer segment beta-catenin binding, gamma-catenin binding, protein binding, protein kinase binding, protein tyrosine phosphatase activity, transmembrane receptor protein tyrosine phosphatase activity Human InterPro:IPR000998 PTPRM GOC UniProtKB {GO:0031290=PMID:15080886, GO:0005515=PMID:11278757, GO:0048471=PMID:15491993, GO:0045296=PMID:9531566, GO:0042493=PMID:18566238, GO:0010842=PMID:14623235, GO:0035335=PMID:8393854, GO:0030027=PMID:15706045, GO:0031175=PMID:16380380, GO:0007165=PMID:15080886, GO:0010596=PMID:18566238, GO:0005737=PMID:16380380, GO:0005913=PMID:17965016, GO:0006470=PMID:8393854, GO:0016020=GO_REF:0000002, GO:0005911=PMID:16380380, GO:0005887=PMID:1655529, GO:0005001=PMID:10809770, GO:0001937=PMID:18566238, GO:0045909=GO_REF:0000019, GO:0016525=PMID:18566238, GO:0007156=PMID:8393854, GO:0004725=PMID:8393854} P28827 Receptor-type tyrosine-protein phosphatase mu protein 20130413 {GO:0031290=IDA, GO:0005515=IPI, GO:0048471=IDA, GO:0045296=IDA, GO:0042493=IDA, GO:0010842=IMP, GO:0035335=IDA, GO:0030027=IDA, GO:0031175=IDA, GO:0007165=IDA, GO:0010596=IMP, GO:0005737=IDA, GO:0005913=IDA, GO:0006470=IDA, GO:0016020=IEA, GO:0005911=IDA, GO:0005887=NAS, GO:0005001=IDA, GO:0001937=IMP, GO:0045909=IEA, GO:0016525=IMP, GO:0007156=IDA, GO:0004725=IDA} homophilic cell adhesion, negative regulation of angiogenesis, negative regulation of endothelial cell migration, negative regulation of endothelial cell proliferation, neuron projection development, peptidyl-tyrosine dephosphorylation, positive regulation of vasodilation, protein dephosphorylation, response to drug, retina layer formation, retinal ganglion cell axon guidance, signal transduction cell-cell adherens junction, cell-cell junction, cytoplasm, integral to plasma membrane, lamellipodium, membrane, perinuclear region of cytoplasm cadherin binding, protein binding, protein tyrosine phosphatase activity, transmembrane receptor protein tyrosine phosphatase activity Human PTPRN BHF-UCL UniProtKB {GO:0005515=PMID:16273344, GO:0032868=GO_REF:0000019, GO:0043627=GO_REF:0000019, GO:0019221=GO_REF:0000019, GO:0030507=PMID:11086001, GO:0051591=GO_REF:0000019, GO:0009749=GO_REF:0000019, GO:0051020=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0005001=PMID:8024693, GO:0005887=PMID:8024693, GO:0000302=PMID:18048354, GO:0004725=GO_REF:0000002} Q16849 Receptor-type tyrosine-protein phosphatase-like N protein 20120926 {GO:0005515=IPI, GO:0032868=IEA, GO:0043627=IEA, GO:0019221=IEA, GO:0030507=IPI, GO:0051591=IEA, GO:0009749=IEA, GO:0051020=IEA, GO:0016020=IEA, GO:0005001=TAS, GO:0005887=TAS, GO:0000302=IDA, GO:0004725=IEA} cytokine-mediated signaling pathway, response to cAMP, response to estrogen stimulus, response to glucose stimulus, response to insulin stimulus, response to reactive oxygen species integral to plasma membrane, membrane GTPase binding, protein binding, protein tyrosine phosphatase activity, spectrin binding, transmembrane receptor protein tyrosine phosphatase activity Human UniProtKB:Q9H254 PTPRN2 PINC UniProtKB {GO:0006470=PMID:8798755, GO:0005887=PMID:8798755, GO:0005001=PMID:8798755, GO:0043195=GO_REF:0000019, GO:0005788=GO_REF:0000019, GO:0030141=GO_REF:0000019, GO:0034260=GO_REF:0000019, GO:0004725=GO_REF:0000002, GO:0030658=GO_REF:0000039} Q92932 Receptor-type tyrosine-protein phosphatase N2 protein 20030904 {GO:0006470=TAS, GO:0005887=TAS, GO:0005001=TAS, GO:0043195=IEA, GO:0005788=IEA, GO:0030141=IEA, GO:0034260=IEA, GO:0004725=IEA, GO:0030658=IEA} negative regulation of GTPase activity, protein dephosphorylation endoplasmic reticulum lumen, integral to plasma membrane, secretory granule, terminal bouton, transport vesicle membrane protein tyrosine phosphatase activity, transmembrane receptor protein tyrosine phosphatase activity Human PTPRO IntAct UniProtKB {GO:0005515=PMID:19167335, GO:0072112=GO_REF:0000024, GO:0043005=GO_REF:0000024, GO:0030424=GO_REF:0000024, GO:0017147=GO_REF:0000024, GO:0090260=GO_REF:0000024, GO:0036060=GO_REF:0000024, GO:0005886=GO_REF:0000024, GO:0030032=GO_REF:0000024, GO:0010812=GO_REF:0000024, GO:0035335=PMID:19233845, GO:0032835=PMID:21722858, GO:0042803=GO_REF:0000024, GO:0030426=GO_REF:0000024, GO:0016791=GO_REF:0000024, GO:0016324=GO_REF:0000024, GO:0006470=GO_REF:0000024, GO:0043197=GO_REF:0000024, GO:0005001=PMID:7665166, GO:0007411=GO_REF:0000024, GO:0090090=GO_REF:0000024, GO:0004725=PMID:19233845, GO:0016328=GO_REF:0000024, GO:0003105=GO_REF:0000024, GO:0030027=GO_REF:0000024, GO:0002548=PMID:19233845, GO:0000902=GO_REF:0000024, GO:0005887=PMID:7665166, GO:0003093=GO_REF:0000024, GO:0010977=GO_REF:0000024, GO:0016021=PMID:10498613} Q16827 Receptor-type tyrosine-protein phosphatase O protein 20130415 {GO:0005515=IPI, GO:0072112=ISS, GO:0043005=ISS, GO:0030424=ISS, GO:0017147=ISS, GO:0090260=ISS, GO:0036060=ISS, GO:0005886=ISS, GO:0030032=ISS, GO:0010812=ISS, GO:0035335=IMP, GO:0032835=IMP, GO:0042803=ISS, GO:0030426=ISS, GO:0016791=ISS, GO:0016324=ISS, GO:0006470=ISS, GO:0043197=ISS, GO:0005001=NAS, GO:0007411=ISS, GO:0090090=ISS, GO:0004725=IMP, GO:0016328=ISS, GO:0003105=ISS, GO:0030027=ISS, GO:0002548=IMP, GO:0000902=ISS, GO:0005887=NAS, GO:0003093=ISS, GO:0010977=ISS, GO:0016021=TAS} axon guidance, cell morphogenesis, glomerular visceral epithelial cell differentiation, glomerulus development, lamellipodium assembly, monocyte chemotaxis, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cell-substrate adhesion, negative regulation of glomerular filtration, negative regulation of neuron projection development, negative regulation of retinal ganglion cell axon guidance, peptidyl-tyrosine dephosphorylation, protein dephosphorylation, regulation of glomerular filtration, slit diaphragm assembly apical plasma membrane, axon, dendritic spine, growth cone, integral to membrane, integral to plasma membrane, lamellipodium, lateral plasma membrane, neuron projection, plasma membrane Wnt-protein binding, phosphatase activity, protein binding, protein homodimerization activity, protein tyrosine phosphatase activity, transmembrane receptor protein tyrosine phosphatase activity Human UniProtKB:Q02763 PTPRR HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0048471=GO_REF:0000039, GO:0006470=PMID:7836467, GO:0009986=PMID:12493773, GO:0005886=GO_REF:0000039, GO:0019901=GO_REF:0000024, GO:0005001=PMID:7836467, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0016021=GO_REF:0000037, GO:0001701=PMID:10601328, GO:0004725=PMID:7836467} Q15256 Receptor-type tyrosine-protein phosphatase R protein 20120912 {GO:0005737=IDA, GO:0048471=IEA, GO:0006470=TAS, GO:0009986=IDA, GO:0005886=IEA, GO:0019901=ISS, GO:0005001=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0016021=IEA, GO:0001701=IEP, GO:0004725=TAS} in utero embryonic development, protein dephosphorylation cell surface, cytoplasm, integral to membrane, nucleolus, nucleus, perinuclear region of cytoplasm, plasma membrane protein kinase binding, protein tyrosine phosphatase activity, transmembrane receptor protein tyrosine phosphatase activity Human PTPRS IntAct UniProtKB {GO:0005515=PMID:16273344, GO:0022038=GO_REF:0000019, GO:0021766=GO_REF:0000019, GO:0021987=GO_REF:0000019, GO:0021510=GO_REF:0000019, GO:0005887=PMID:8524829, GO:0005001=PMID:8524829, GO:0021549=GO_REF:0000019, GO:0007155=GO_REF:0000037, GO:0004725=GO_REF:0000002} Q13332 Receptor-type tyrosine-protein phosphatase S protein 20130415 {GO:0005515=IPI, GO:0022038=IEA, GO:0021766=IEA, GO:0021987=IEA, GO:0021510=IEA, GO:0005887=TAS, GO:0005001=TAS, GO:0021549=IEA, GO:0007155=IEA, GO:0004725=IEA} cell adhesion, cerebellum development, cerebral cortex development, corpus callosum development, hippocampus development, spinal cord development integral to plasma membrane protein binding, protein tyrosine phosphatase activity, transmembrane receptor protein tyrosine phosphatase activity Human UniProtKB:Q16849 PTPRT GOC UniProtKB {GO:0005515=PMID:16273344, GO:0045296=PMID:16973135, GO:0009986=PMID:18644975, GO:0005886=PMID:18644975, GO:0008013=PMID:16973135, GO:0045295=PMID:16973135, GO:0070097=PMID:16973135, GO:0045294=PMID:16973135, GO:0035335=PMID:17360477, GO:0007165=PMID:16973135, GO:0006470=PMID:16973135, GO:0016020=GO_REF:0000002, GO:0051393=GO_REF:0000019, GO:0016021=PMID:9602027, GO:0007155=PMID:16973135, GO:0007169=PMID:16973135, GO:0007156=PMID:18644975, GO:0004725=GO_REF:0000002, GO:0016790=GO_REF:0000019} O14522 Receptor-type tyrosine-protein phosphatase T protein 20130413 {GO:0005515=IPI, GO:0045296=IPI, GO:0009986=IDA, GO:0005886=IDA, GO:0008013=IPI, GO:0045295=IDA, GO:0070097=IPI, GO:0045294=IDA, GO:0035335=IMP, GO:0007165=NAS, GO:0006470=IDA, GO:0016020=IEA, GO:0051393=IEA, GO:0016021=NAS, GO:0007155=NAS, GO:0007169=IMP, GO:0007156=IDA, GO:0004725=IEA, GO:0016790=IEA} cell adhesion, homophilic cell adhesion, peptidyl-tyrosine dephosphorylation, protein dephosphorylation, signal transduction, transmembrane receptor protein tyrosine kinase signaling pathway cell surface, integral to membrane, membrane, plasma membrane alpha-actinin binding, alpha-catenin binding, beta-catenin binding, cadherin binding, delta-catenin binding, gamma-catenin binding, protein binding, protein tyrosine phosphatase activity, thiolester hydrolase activity Human PTPRU GOC UniProtKB {GO:0005515=PMID:17622474, GO:0030336=PMID:16574648, GO:0008285=PMID:16574648, GO:0005886=Reactome:REACT_111127, GO:0008013=PMID:16574648, GO:0035335=PMID:16574648, GO:0030154=GO_REF:0000037, GO:0016337=PMID:16574648, GO:0034109=GO_REF:0000019, GO:0006470=PMID:12501215, GO:0016020=GO_REF:0000002, GO:0005887=PMID:8700514, GO:0005001=PMID:8700514, GO:0005911=PMID:12501215, GO:0034394=PMID:16574648, GO:0007185=PMID:8700514, GO:0007155=PMID:8700514, GO:0060070=PMID:16574648, GO:0004725=PMID:12501215} Q92729 Receptor-type tyrosine-protein phosphatase U protein 20130413 {GO:0005515=IPI, GO:0030336=IDA, GO:0008285=IDA, GO:0005886=TAS, GO:0008013=IPI, GO:0035335=IMP, GO:0030154=IEA, GO:0016337=IDA, GO:0034109=IEA, GO:0006470=IDA, GO:0016020=IEA, GO:0005887=NAS, GO:0005001=NAS, GO:0005911=IDA, GO:0034394=IDA, GO:0007185=NAS, GO:0007155=NAS, GO:0060070=IDA, GO:0004725=IDA} canonical Wnt receptor signaling pathway, cell adhesion, cell differentiation, cell-cell adhesion, homotypic cell-cell adhesion, negative regulation of cell migration, negative regulation of cell proliferation, peptidyl-tyrosine dephosphorylation, protein dephosphorylation, protein localization to cell surface, transmembrane receptor protein tyrosine phosphatase signaling pathway cell-cell junction, integral to plasma membrane, membrane, plasma membrane beta-catenin binding, protein binding, protein tyrosine phosphatase activity, transmembrane receptor protein tyrosine phosphatase activity Human PTPRZ1 PINC UniProtKB {GO:0072534=GO_REF:0000019, GO:0006470=PMID:1323835, GO:0005887=PMID:8387522, GO:0005001=PMID:1323835, GO:0008330=PMID:9653645, GO:0005578=GO_REF:0000019, GO:0007409=GO_REF:0000019, GO:0007417=PMID:8387522, GO:0004725=GO_REF:0000002} P23471 Receptor-type tyrosine-protein phosphatase zeta protein 20030904 {GO:0072534=IEA, GO:0006470=TAS, GO:0005887=TAS, GO:0005001=TAS, GO:0008330=NAS, GO:0005578=IEA, GO:0007409=IEA, GO:0007417=TAS, GO:0004725=IEA} axonogenesis, central nervous system development, protein dephosphorylation integral to plasma membrane, perineuronal net, proteinaceous extracellular matrix protein tyrosine phosphatase activity, protein tyrosine/threonine phosphatase activity, transmembrane receptor protein tyrosine phosphatase activity Human PTRF Reactome UniProtKB {GO:0005515=PMID:17026959, GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000037, GO:0005783=GO_REF:0000039, GO:0006363=Reactome:REACT_1074, GO:0006361=PMID:9582279, GO:0005634=PMID:15242332, GO:0006360=Reactome:REACT_1309, GO:0005829=GO_REF:0000039, GO:0005739=PMID:15242332, GO:0005737=PMID:17026959, GO:0005901=PMID:17026959, GO:0005654=Reactome:REACT_513, GO:0042134=PMID:9582279} Q6NZI2 Polymerase I and transcript release factor protein 20130213 {GO:0005515=IPI, GO:0010467=TAS, GO:0006355=IEA, GO:0005783=IEA, GO:0006363=TAS, GO:0006361=IDA, GO:0005634=IDA, GO:0006360=TAS, GO:0005829=IEA, GO:0005739=IDA, GO:0005737=IDA, GO:0005901=IDA, GO:0005654=TAS, GO:0042134=IDA} gene expression, regulation of transcription, DNA-dependent, termination of RNA polymerase I transcription, transcription from RNA polymerase I promoter, transcription initiation from RNA polymerase I promoter caveola, cytoplasm, cytosol, endoplasmic reticulum, mitochondrion, nucleoplasm, nucleus protein binding, rRNA primary transcript binding Human PTRH1 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0004045=GO_REF:0000003} Q86Y79 Probable peptidyl-tRNA hydrolase protein 20130413 {GO:0005739=IEA, GO:0004045=IEA} mitochondrion aminoacyl-tRNA hydrolase activity Human Ensembl:ENSMUSP00000068850 PTRH2 IntAct UniProtKB {GO:0005515=PMID:22952044, GO:0005739=PMID:22952044, GO:0006915=GO_REF:0000037, GO:0004045=GO_REF:0000003} Q9Y3E5 Peptidyl-tRNA hydrolase 2, mitochondrial protein 20130415 {GO:0005515=IPI, GO:0005739=IMP, GO:0006915=IEA, GO:0004045=IEA} apoptotic process mitochondrion aminoacyl-tRNA hydrolase activity, protein binding Human UniProtKB:Q08117 PTS IntAct UniProtKB {GO:0006520=PMID:3308682, GO:0003874=Reactome:REACT_111082, GO:0006729=GO_REF:0000041, GO:0050999=Reactome:REACT_12389, GO:0044281=Reactome:REACT_111217, GO:0007417=PMID:3308682, GO:0042803=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_111245, GO:0042802=PMID:16189514, GO:0005739=GO_REF:0000054, GO:0005737=GO_REF:0000054, GO:0046209=Reactome:REACT_12508} Q03393 6-pyruvoyl tetrahydrobiopterin synthase protein 20130415 {GO:0006520=TAS, GO:0003874=TAS, GO:0006729=IEA, GO:0050999=TAS, GO:0044281=TAS, GO:0007417=TAS, GO:0042803=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0042802=IPI, GO:0005739=IDA, GO:0005737=IDA, GO:0046209=TAS} cellular amino acid metabolic process, central nervous system development, nitric oxide metabolic process, regulation of nitric-oxide synthase activity, small molecule metabolic process, tetrahydrobiopterin biosynthetic process cytoplasm, cytosol, mitochondrion 6-pyruvoyltetrahydropterin synthase activity, identical protein binding, metal ion binding, protein homodimerization activity Human UniProtKB:Q03393 PTTG1 GOC UniProtKB {GO:0005515=PMID:12194817, GO:0006355=PMID:9811450, GO:0051276=GO_REF:0000002, GO:0017124=GO_REF:0000037, GO:0004869=PMID:12194817, GO:0003700=PMID:9811450, GO:0006366=PMID:9811450, GO:0005634=GO_REF:0000052, GO:0006259=GO_REF:0000002, GO:0007283=PMID:9915854, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_150297, GO:0005737=GO_REF:0000052, GO:0006281=GO_REF:0000037, GO:0007059=GO_REF:0000037, GO:0000087=Reactome:REACT_910, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} O95997 Securin protein 20130413 {GO:0005515=IPI, GO:0006355=TAS, GO:0051276=IEA, GO:0017124=IEA, GO:0004869=NAS, GO:0003700=TAS, GO:0006366=TAS, GO:0005634=IDA, GO:0006259=IEA, GO:0007283=TAS, GO:0031145=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0006281=IEA, GO:0007059=IEA, GO:0000087=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} DNA metabolic process, DNA repair, M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell division, chromosome organization, chromosome segregation, mitotic anaphase, mitotic cell cycle, regulation of transcription, DNA-dependent, spermatogenesis, transcription from RNA polymerase II promoter cytoplasm, cytosol, nucleus SH3 domain binding, cysteine-type endopeptidase inhibitor activity, protein binding, sequence-specific DNA binding transcription factor activity Human PTTG1IP UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0005737=PMID:10781616, GO:0016020=GO_REF:0000029, GO:0005634=PMID:10781616, GO:0016021=GO_REF:0000037, GO:0006606=PMID:10781616} P53801 Pituitary tumor-transforming gene 1 protein-interacting protein protein 20061026 {GO:0003674=ND, GO:0005737=IDA, GO:0016020=NAS, GO:0005634=IDA, GO:0016021=IEA, GO:0006606=IDA} protein import into nucleus cytoplasm, integral to membrane, membrane, nucleus molecular_function Human PTTG2 HPA UniProtKB {GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0017124=GO_REF:0000037, GO:0051276=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0006259=GO_REF:0000002} Q9NZH5 Securin-2 protein 20080205 {GO:0003674=ND, GO:0005737=IDA, GO:0017124=IEA, GO:0051276=IEA, GO:0005634=IDA, GO:0006259=IEA} DNA metabolic process, chromosome organization cytoplasm, nucleus SH3 domain binding, molecular_function Human PTX3 PINC UniProtKB {GO:0050766=GO_REF:0000019, GO:0006954=PMID:1429570, GO:0005576=GO_REF:0000039, GO:0001872=GO_REF:0000019, GO:0001878=GO_REF:0000019, GO:0008228=GO_REF:0000019, GO:0045429=GO_REF:0000019} P26022 Pentraxin-related protein PTX3 protein 20030904 {GO:0050766=IEA, GO:0006954=TAS, GO:0005576=IEA, GO:0001872=IEA, GO:0001878=IEA, GO:0008228=IEA, GO:0045429=IEA} inflammatory response, opsonization, positive regulation of nitric oxide biosynthetic process, positive regulation of phagocytosis, response to yeast extracellular region (1->3)-beta-D-glucan binding Human PUF60 HPA UniProtKB {GO:0005515=PMID:21078624, GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0006355=GO_REF:0000037, GO:0019907=PMID:11445587, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0030529=GO_REF:0000037} Q9UHX1 Poly(U)-binding-splicing factor PUF60 protein 20111111 {GO:0005515=IPI, GO:0008380=IEA, GO:0006397=IEA, GO:0006355=IEA, GO:0019907=IDA, GO:0003723=IEA, GO:0005730=IDA, GO:0006915=IEA, GO:0005634=IDA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0000166=IEA, GO:0030529=IEA} RNA splicing, apoptotic process, mRNA processing, regulation of transcription, DNA-dependent, transcription, DNA-dependent cyclin-dependent protein kinase activating kinase holoenzyme complex, nucleolus, nucleus, ribonucleoprotein complex DNA binding, RNA binding, nucleic acid binding, nucleotide binding, protein binding NOT Human PUM1 InterPro UniProtKB {GO:0003723=GO_REF:0000002, GO:0006892=Reactome:REACT_11235, GO:0016044=Reactome:REACT_11123, GO:0006417=GO_REF:0000037, GO:0005829=Reactome:REACT_19237} Q5T1Z8 Pumilio homolog 1 protein 20130413 {GO:0003723=IEA, GO:0006892=TAS, GO:0016044=TAS, GO:0006417=IEA, GO:0005829=TAS} cellular membrane organization, post-Golgi vesicle-mediated transport, regulation of translation cytosol RNA binding Human InterPro:IPR001313 PUM2 HPA UniProtKB {GO:0005515=PMID:22190034, GO:0048471=PMID:19168546, GO:0005737=GO_REF:0000052, GO:0034063=GO_REF:0000019, GO:0010494=GO_REF:0000024, GO:0003723=GO_REF:0000019, GO:0006417=GO_REF:0000037} Q8TB72 Pumilio homolog 2 protein 20101115 {GO:0005515=IPI, GO:0048471=IDA, GO:0005737=IDA, GO:0034063=IEA, GO:0010494=ISS, GO:0003723=IEA, GO:0006417=IEA} regulation of translation, stress granule assembly cytoplasm, cytoplasmic stress granule, perinuclear region of cytoplasm RNA binding, protein binding Human PURA IntAct UniProtKB {GO:0005515=PMID:7592647, GO:0008284=GO_REF:0000019, GO:0003705=PMID:9334258, GO:0005634=PMID:9716182, GO:0046332=GO_REF:0000019, GO:0032422=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0007399=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0003691=PMID:15777841, GO:0003697=GO_REF:0000024, GO:0006270=PMID:1545807, GO:0043025=GO_REF:0000019, GO:0006268=PMID:15777841, GO:0005662=GO_REF:0000024, GO:0045892=GO_REF:0000019, GO:0000784=PMID:15777841, GO:0008134=GO_REF:0000024, GO:0000900=GO_REF:0000019} Q00577 Transcriptional activator protein Pur-alpha protein 20130415 {GO:0005515=IPI, GO:0008284=IEA, GO:0003705=TAS, GO:0005634=IDA, GO:0046332=IEA, GO:0032422=IEA, GO:0030425=IEA, GO:0007399=IEA, GO:0005737=IEA, GO:0003691=IDA, GO:0003697=ISS, GO:0006270=TAS, GO:0043025=IEA, GO:0006268=IDA, GO:0005662=ISS, GO:0045892=IEA, GO:0000784=IC, GO:0008134=ISS, GO:0000900=IEA} DNA replication initiation, DNA unwinding involved in replication, negative regulation of transcription, DNA-dependent, nervous system development, positive regulation of cell proliferation DNA replication factor A complex, cytoplasm, dendrite, neuronal cell body, nuclear chromosome, telomeric region, nucleus RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, SMAD binding, double-stranded telomeric DNA binding, protein binding, purine-rich negative regulatory element binding, single-stranded DNA binding, transcription factor binding, translation repressor activity, nucleic acid binding Human UniProtKB:P06400 PURB HPA UniProtKB {GO:0003700=GO_REF:0000019, GO:0003690=GO_REF:0000019, GO:0003697=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0045637=PMID:11417483, GO:0046332=GO_REF:0000019, GO:0003729=GO_REF:0000024, GO:0005662=GO_REF:0000024, GO:0045892=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0008134=GO_REF:0000024} Q96QR8 Transcriptional activator protein Pur-beta protein 20120912 {GO:0003700=IEA, GO:0003690=IEA, GO:0003697=ISS, GO:0005634=IDA, GO:0045637=NAS, GO:0046332=IEA, GO:0003729=ISS, GO:0005662=ISS, GO:0045892=IEA, GO:0006351=IEA, GO:0008134=ISS} negative regulation of transcription, DNA-dependent, regulation of myeloid cell differentiation, transcription, DNA-dependent DNA replication factor A complex, nucleus SMAD binding, double-stranded DNA binding, mRNA binding, sequence-specific DNA binding transcription factor activity, single-stranded DNA binding, transcription factor binding Human PURG UniProtKB UniProtKB {GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037} Q9UJV8 Purine-rich element-binding protein gamma protein 20130413 {GO:0005634=IEA, GO:0003677=IEA} nucleus DNA binding Human UniProtKB-SubCell:SL-0191 PUS1 UniProtKB UniProtKB {GO:0009982=GO_REF:0000003, GO:0005667=GO_REF:0000019, GO:0004730=PMID:10094309, GO:0003723=GO_REF:0000002, GO:0005730=GO_REF:0000019, GO:0005634=GO_REF:0000029, GO:0001522=GO_REF:0000002, GO:0003677=GO_REF:0000019, GO:0031119=GO_REF:0000019, GO:0008033=GO_REF:0000029, GO:0005739=GO_REF:0000039, GO:0030374=GO_REF:0000019, GO:0045944=GO_REF:0000019} Q9Y606 tRNA pseudouridine synthase A, mitochondrial protein 20021104 {GO:0009982=IEA, GO:0005667=IEA, GO:0004730=NAS, GO:0003723=IEA, GO:0005730=IEA, GO:0005634=NAS, GO:0001522=IEA, GO:0003677=IEA, GO:0031119=IEA, GO:0008033=NAS, GO:0005739=IEA, GO:0030374=IEA, GO:0045944=IEA} positive regulation of transcription from RNA polymerase II promoter, pseudouridine synthesis, tRNA processing, tRNA pseudouridine synthesis mitochondrion, nucleolus, nucleus, transcription factor complex DNA binding, RNA binding, ligand-dependent nuclear receptor transcription coactivator activity, pseudouridine synthase activity, pseudouridylate synthase activity Human PUS7 UniProtKB UniProtKB {GO:0009982=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0001522=GO_REF:0000002, GO:0008033=GO_REF:0000037} Q96PZ0 Pseudouridylate synthase 7 homolog protein 20130413 {GO:0009982=IEA, GO:0003723=IEA, GO:0001522=IEA, GO:0008033=IEA} pseudouridine synthesis, tRNA processing RNA binding, pseudouridine synthase activity Human UniProtKB-KW:KW-0819 PUS7L UniProtKB UniProtKB {GO:0009982=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0001522=GO_REF:0000002, GO:0008033=GO_REF:0000037} Q9H0K6 Pseudouridylate synthase 7 homolog-like protein protein 20130413 {GO:0009982=IEA, GO:0003723=IEA, GO:0001522=IEA, GO:0008033=IEA} pseudouridine synthesis, tRNA processing RNA binding, pseudouridine synthase activity Human UniProtKB-KW:KW-0819 PUSL1 UniProtKB UniProtKB {GO:0009982=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0001522=GO_REF:0000002, GO:0008033=GO_REF:0000037} Q8N0Z8 tRNA pseudouridine synthase-like 1 protein 20130413 {GO:0009982=IEA, GO:0003723=IEA, GO:0001522=IEA, GO:0008033=IEA} pseudouridine synthesis, tRNA processing RNA binding, pseudouridine synthase activity Human UniProtKB-KW:KW-0819 PVALB ENSEMBL UniProtKB {GO:0030424=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0005509=GO_REF:0000002} P20472 Parvalbumin alpha protein 20130413 {GO:0030424=IEA, GO:0005737=IEA, GO:0005509=IEA} axon, cytoplasm calcium ion binding Human Ensembl:ENSMUSP00000005860 PVR HPA UniProtKB {GO:0005515=PMID:19011627, GO:0030054=GO_REF:0000052, GO:0009986=PMID:16831868, GO:0005886=GO_REF:0000052, GO:0034329=Reactome:REACT_20676, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005615=PMID:2170108, GO:0045216=Reactome:REACT_19331, GO:0043231=GO_REF:0000052, GO:0060370=PMID:15039383, GO:0016337=GO_REF:0000019, GO:0005737=PMID:2170108, GO:0016477=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0050776=Reactome:REACT_11152, GO:0045954=PMID:16304049, GO:0042271=PMID:12913096, GO:0002860=PMID:12913096, GO:0004872=PMID:2538245, GO:0016021=PMID:12913096, GO:0050839=PMID:12913096, GO:0034332=Reactome:REACT_19195} P15151 Poliovirus receptor protein 20100326 {GO:0005515=IPI, GO:0030054=IDA, GO:0009986=IDA, GO:0005886=IDA, GO:0034329=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0005615=TAS, GO:0045216=TAS, GO:0043231=IDA, GO:0060370=IDA, GO:0016337=IEA, GO:0005737=TAS, GO:0016477=IEA, GO:0019048=IEA, GO:0050776=TAS, GO:0045954=IMP, GO:0042271=IMP, GO:0002860=IMP, GO:0004872=TAS, GO:0016021=IDA, GO:0050839=IPI, GO:0034332=TAS} adherens junction organization, cell junction assembly, cell migration, cell-cell adhesion, cell-cell junction organization, positive regulation of natural killer cell mediated cytotoxicity, positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, regulation of immune response, susceptibility to T cell mediated cytotoxicity, susceptibility to natural killer cell mediated cytotoxicity, virus-host interaction cell junction, cell surface, cytoplasm, extracellular space, integral to membrane, intracellular membrane-bounded organelle, nucleolus, nucleus, plasma membrane cell adhesion molecule binding, protein binding, receptor activity Human PVRL1 BHF-UCL UniProtKB {GO:0005515=PMID:21982860, GO:0005886=Reactome:REACT_19364, GO:0060041=GO_REF:0000019, GO:0034329=Reactome:REACT_20676, GO:0070166=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0015026=PMID:9616127, GO:0046718=PMID:12885915, GO:0045216=Reactome:REACT_19331, GO:0042803=GO_REF:0000024, GO:0006955=PMID:10932188, GO:0016337=PMID:12885915, GO:0005913=PMID:10225955, GO:0002934=GO_REF:0000019, GO:0005912=PMID:12885915, GO:0016020=PMID:9616127, GO:0002089=GO_REF:0000019, GO:0006826=GO_REF:0000019, GO:0016021=PMID:10932188, GO:0007155=PMID:12764381, GO:0050839=PMID:12438620, GO:0007156=GO_REF:0000024, GO:0007157=GO_REF:0000024, GO:0034332=Reactome:REACT_19195} Q15223 Poliovirus receptor-related protein 1 protein 20081127 {GO:0005515=IPI, GO:0005886=TAS, GO:0060041=IEA, GO:0034329=TAS, GO:0070166=IEA, GO:0005576=IEA, GO:0015026=TAS, GO:0046718=NAS, GO:0045216=TAS, GO:0042803=ISS, GO:0006955=NAS, GO:0016337=NAS, GO:0005913=IDA, GO:0002934=IEA, GO:0005912=NAS, GO:0016020=TAS, GO:0002089=IEA, GO:0006826=IEA, GO:0016021=NAS, GO:0007155=NAS, GO:0050839=IPI, GO:0007156=ISS, GO:0007157=ISS, GO:0034332=TAS} adherens junction organization, cell adhesion, cell junction assembly, cell-cell adhesion, cell-cell junction organization, desmosome organization, enamel mineralization, heterophilic cell-cell adhesion, homophilic cell adhesion, immune response, iron ion transport, lens morphogenesis in camera-type eye, retina development in camera-type eye, viral entry into host cell adherens junction, cell-cell adherens junction, extracellular region, integral to membrane, membrane, plasma membrane cell adhesion molecule binding, coreceptor activity, protein binding, protein homodimerization activity Human UniProtKB:Q9NQS3 PVRL2 BHF-UCL UniProtKB {GO:0005515=PMID:21982860, GO:0001675=GO_REF:0000019, GO:0005886=Reactome:REACT_19364, GO:0007289=GO_REF:0000019, GO:0007286=GO_REF:0000024, GO:0051856=PMID:12915581, GO:0033005=PMID:16831868, GO:0030382=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0060370=PMID:15039383, GO:0005915=PMID:10225955, GO:0005911=PMID:9845526, GO:0007010=GO_REF:0000019, GO:0042271=PMID:12913096, GO:0002891=PMID:16831868, GO:0007156=PMID:9845526, GO:0050839=PMID:12913096, GO:0043064=GO_REF:0000019, GO:0009986=PMID:16831868, GO:0034329=Reactome:REACT_20676, GO:0019064=PMID:12915581, GO:0015026=PMID:9657005, GO:0032990=GO_REF:0000019, GO:0045216=Reactome:REACT_19331, GO:0009566=GO_REF:0000019, GO:0051654=GO_REF:0000019, GO:0050776=Reactome:REACT_11152, GO:0045954=PMID:16304049, GO:0002860=PMID:12913096, GO:0016021=PMID:12913096, GO:0046814=PMID:12915581, GO:0034332=Reactome:REACT_19195} Q92692 Poliovirus receptor-related protein 2 protein 20090424 {GO:0005515=IPI, GO:0001675=IEA, GO:0005886=TAS, GO:0007289=IEA, GO:0007286=ISS, GO:0051856=IDA, GO:0033005=IMP, GO:0030382=IEA, GO:0042803=IEA, GO:0060370=IDA, GO:0005915=ISS, GO:0005911=IDA, GO:0007010=IEA, GO:0042271=IMP, GO:0002891=IMP, GO:0007156=IDA, GO:0050839=IPI, GO:0043064=IEA, GO:0009986=IDA, GO:0034329=TAS, GO:0019064=IDA, GO:0015026=TAS, GO:0032990=IEA, GO:0045216=TAS, GO:0009566=IEA, GO:0051654=IEA, GO:0050776=TAS, GO:0045954=IMP, GO:0002860=IMP, GO:0016021=IDA, GO:0046814=IDA, GO:0034332=TAS} acrosome assembly, adherens junction organization, adhesion to symbiont, cell junction assembly, cell part morphogenesis, cell-cell junction organization, cytoskeleton organization, establishment of mitochondrion localization, fertilization, flagellum organization, homophilic cell adhesion, positive regulation of immunoglobulin mediated immune response, positive regulation of mast cell activation, positive regulation of natural killer cell mediated cytotoxicity, positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, regulation of immune response, sperm mitochondrion organization, spermatid development, spermatid nucleus differentiation, susceptibility to T cell mediated cytotoxicity, susceptibility to natural killer cell mediated cytotoxicity, viral entry into host cell via membrane fusion with the plasma membrane, virion attachment, binding of host cell surface coreceptor cell surface, cell-cell junction, integral to membrane, plasma membrane, zonula adherens cell adhesion molecule binding, coreceptor activity, protein binding, protein homodimerization activity Human PVRL3 BHF-UCL UniProtKB {GO:0005515=PMID:21982860, GO:0005886=Reactome:REACT_19364, GO:0034329=Reactome:REACT_20676, GO:0060042=GO_REF:0000019, GO:0042803=GO_REF:0000024, GO:0045216=Reactome:REACT_19331, GO:0009566=GO_REF:0000019, GO:0043296=GO_REF:0000019, GO:0005913=GO_REF:0000019, GO:0002089=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0050839=PMID:12438620, GO:0007156=GO_REF:0000024, GO:0034332=Reactome:REACT_19195} Q9NQS3 Poliovirus receptor-related protein 3 protein 20081127 {GO:0005515=IPI, GO:0005886=TAS, GO:0034329=TAS, GO:0060042=IEA, GO:0042803=ISS, GO:0045216=TAS, GO:0009566=IEA, GO:0043296=IEA, GO:0005913=IEA, GO:0002089=IEA, GO:0016021=IEA, GO:0050839=IPI, GO:0007156=ISS, GO:0034332=TAS} adherens junction organization, cell junction assembly, cell-cell junction organization, fertilization, homophilic cell adhesion, lens morphogenesis in camera-type eye, retina morphogenesis in camera-type eye apical junction complex, cell-cell adherens junction, integral to membrane, plasma membrane cell adhesion molecule binding, protein binding, protein homodimerization activity Human UniProtKB:Q15223 PVRL4 IntAct UniProtKB {GO:0005515=PMID:22048310, GO:0005886=Reactome:REACT_19364, GO:0005912=GO_REF:0000039, GO:0034329=Reactome:REACT_20676, GO:0019048=GO_REF:0000037, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037, GO:0045216=Reactome:REACT_19331, GO:0034332=Reactome:REACT_19195} Q96NY8 Poliovirus receptor-related protein 4 protein 20130415 {GO:0005515=IPI, GO:0005886=TAS, GO:0005912=IEA, GO:0034329=TAS, GO:0019048=IEA, GO:0005576=IEA, GO:0016021=IEA, GO:0007155=IEA, GO:0045216=TAS, GO:0034332=TAS} adherens junction organization, cell adhesion, cell junction assembly, cell-cell junction organization, virus-host interaction adherens junction, extracellular region, integral to membrane, plasma membrane protein binding Human UniProtKB:Q786F2 PWP1 PINC UniProtKB {GO:0005634=GO_REF:0000039, GO:0006351=PMID:7828893} Q13610 Periodic tryptophan protein 1 homolog protein 20030904 {GO:0005634=IEA, GO:0006351=TAS} transcription, DNA-dependent nucleus Human PWP2 HPA UniProtKB {GO:0007165=PMID:8893822, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0004871=PMID:8893822} Q15269 Periodic tryptophan protein 2 homolog protein 20101115 {GO:0007165=TAS, GO:0005737=IDA, GO:0005730=IDA, GO:0004871=TAS} signal transduction cytoplasm, nucleolus signal transducer activity Human PWWP2A null null {} null null null null {} null null null PWWP2B null null {} null null null null {} null null null PXDC1 InterPro UniProtKB {GO:0007154=GO_REF:0000002, GO:0035091=GO_REF:0000002} Q5TGL8 PX domain-containing protein 1 protein 20130413 {GO:0007154=IEA, GO:0035091=IEA} cell communication phosphatidylinositol binding Human InterPro:IPR001683 PXDN GOC UniProtKB {GO:0005783=PMID:19590037, GO:0005578=GO_REF:0000039, GO:0005152=PMID:11103812, GO:0005615=PMID:18929642, GO:0046872=GO_REF:0000037, GO:0031012=PMID:19590037, GO:0006955=PMID:11103812, GO:0004601=PMID:18929642, GO:0001960=PMID:11103812, GO:0030198=PMID:19590037, GO:0042744=PMID:18929642, GO:0006979=GO_REF:0000002, GO:0005201=PMID:19590037, GO:0055114=PMID:18929642, GO:0020037=PMID:18929642} Q92626 Peroxidasin homolog protein 20130413 {GO:0005783=IDA, GO:0005578=IEA, GO:0005152=NAS, GO:0005615=IDA, GO:0046872=IEA, GO:0031012=IDA, GO:0006955=NAS, GO:0004601=IDA, GO:0001960=NAS, GO:0030198=IDA, GO:0042744=IDA, GO:0006979=IEA, GO:0005201=IDA, GO:0055114=IDA, GO:0020037=IDA} extracellular matrix organization, hydrogen peroxide catabolic process, immune response, negative regulation of cytokine-mediated signaling pathway, oxidation-reduction process, response to oxidative stress endoplasmic reticulum, extracellular matrix, extracellular space, proteinaceous extracellular matrix extracellular matrix structural constituent, heme binding, interleukin-1 receptor antagonist activity, metal ion binding, peroxidase activity Human PXDNL InterPro UniProtKB {GO:0005737=GO_REF:0000039, GO:0004601=GO_REF:0000002, GO:0004519=GO_REF:0000037, GO:0042744=GO_REF:0000024, GO:0006979=GO_REF:0000002, GO:0005615=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0055114=GO_REF:0000024, GO:0020037=GO_REF:0000002} K4DIA6 Peroxidasin-like protein protein 20130413 {GO:0005737=IEA, GO:0004601=IEA, GO:0004519=IEA, GO:0042744=ISS, GO:0006979=IEA, GO:0005615=ISS, GO:0046872=IEA, GO:0055114=ISS, GO:0020037=IEA} hydrogen peroxide catabolic process, oxidation-reduction process, response to oxidative stress cytoplasm, extracellular space endonuclease activity, heme binding, metal ion binding, peroxidase activity Human InterPro:IPR002007|InterPro:IPR010255|InterPro:IPR019791 PXK HPA UniProtKB {GO:0005813=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0050804=GO_REF:0000024, GO:0003779=GO_REF:0000037, GO:0032780=GO_REF:0000019, GO:0008022=GO_REF:0000019, GO:0005524=PMID:16142408, GO:0043271=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0006954=PMID:18204446, GO:0007154=GO_REF:0000002, GO:0004672=PMID:16142408, GO:0000166=PMID:16142408, GO:0006468=PMID:16142408, GO:0035091=GO_REF:0000002} Q7Z7A4 PX domain-containing protein kinase-like protein protein 20100326 {GO:0005813=IDA, GO:0005886=IDA, GO:0050804=ISS, GO:0003779=IEA, GO:0032780=IEA, GO:0008022=IEA, GO:0005524=NAS, GO:0043271=IEA, GO:0005737=IDA, GO:0006954=IMP, GO:0007154=IEA, GO:0004672=NAS, GO:0000166=NAS, GO:0006468=NAS, GO:0035091=IEA} cell communication, inflammatory response, negative regulation of ATPase activity, negative regulation of ion transport, protein phosphorylation, regulation of synaptic transmission centrosome, cytoplasm, plasma membrane ATP binding, actin binding, nucleotide binding, phosphatidylinositol binding, protein C-terminus binding, protein kinase activity Human PXMP2 IntAct UniProtKB {GO:0005515=PMID:16683188, GO:0005739=GO_REF:0000019, GO:0008150=GO_REF:0000015, GO:0043234=PMID:18174172, GO:0016021=GO_REF:0000037, GO:0005778=PMID:11590176} Q9NR77 Peroxisomal membrane protein 2 protein 20130415 {GO:0005515=IPI, GO:0005739=IEA, GO:0008150=ND, GO:0043234=IDA, GO:0016021=IEA, GO:0005778=IDA} biological_process integral to membrane, mitochondrion, peroxisomal membrane, protein complex protein binding Human UniProtKB:O15304 PXMP4 LIFEdb UniProtKB {GO:0005515=PMID:14709540, GO:0008150=GO_REF:0000015, GO:0016021=GO_REF:0000037, GO:0005778=PMID:14709540, GO:0005777=GO_REF:0000054} Q9Y6I8 Peroxisomal membrane protein 4 protein 20100607 {GO:0005515=IPI, GO:0008150=ND, GO:0016021=IEA, GO:0005778=IDA, GO:0005777=IDA} biological_process integral to membrane, peroxisomal membrane, peroxisome protein binding Human PXN BHF-UCL UniProtKB {GO:0005515=PMID:16478788, GO:0008013=PMID:17513457, GO:0005886=Reactome:REACT_20663, GO:0030032=GO_REF:0000019, GO:0006928=GO_REF:0000019, GO:0060396=PMID:10925297, GO:0000187=GO_REF:0000019, GO:0006936=Reactome:REACT_20558, GO:0007172=PMID:9054445, GO:0007173=Reactome:REACT_9417, GO:0048041=GO_REF:0000019, GO:0007010=GO_REF:0000019, GO:0005856=GO_REF:0000002, GO:0007155=PMID:10840040, GO:0005938=GO_REF:0000039, GO:0019901=GO_REF:0000019, GO:0034329=Reactome:REACT_20676, GO:0005875=PMID:10840040, GO:0018108=GO_REF:0000019, GO:0051435=GO_REF:0000019, GO:0030027=PMID:12686598, GO:0007165=PMID:7534286, GO:0005178=GO_REF:0000019, GO:0007160=GO_REF:0000002, GO:0007229=GO_REF:0000019, GO:0017166=PMID:9054445, GO:0034614=PMID:12686598, GO:0008270=GO_REF:0000002, GO:0048754=GO_REF:0000019, GO:0005925=PMID:20086044} P49023 Paxillin protein 20100721 {GO:0005515=IPI, GO:0008013=IPI, GO:0005886=TAS, GO:0030032=IEA, GO:0006928=IEA, GO:0060396=IDA, GO:0000187=IEA, GO:0006936=TAS, GO:0007172=TAS, GO:0007173=TAS, GO:0048041=IEA, GO:0007010=IEA, GO:0005856=IEA, GO:0007155=NAS, GO:0005938=IEA, GO:0019901=IEA, GO:0034329=TAS, GO:0005875=TAS, GO:0018108=IEA, GO:0051435=IEA, GO:0030027=IDA, GO:0007165=TAS, GO:0005178=IEA, GO:0007160=IEA, GO:0007229=IEA, GO:0017166=IPI, GO:0034614=IEP, GO:0008270=IEA, GO:0048754=IEA, GO:0005925=IDA} activation of MAPK activity, branching morphogenesis of an epithelial tube, cell adhesion, cell junction assembly, cell-matrix adhesion, cellular component movement, cellular response to reactive oxygen species, cytoskeleton organization, epidermal growth factor receptor signaling pathway, focal adhesion assembly, growth hormone receptor signaling pathway, integrin-mediated signaling pathway, lamellipodium assembly, muscle contraction, peptidyl-tyrosine phosphorylation, signal complex assembly, signal transduction cell cortex, cytoskeleton, focal adhesion, lamellipodium, microtubule associated complex, plasma membrane BH4 domain binding, beta-catenin binding, integrin binding, protein binding, protein kinase binding, vinculin binding, zinc ion binding Human PYCARD IntAct UniProtKB {GO:0005515=PMID:22286270, GO:0032755=GO_REF:0000024, GO:2001056=PMID:19158676, GO:0046330=PMID:21487011, GO:0002218=PMID:21575908, GO:0042803=PMID:15030775, GO:0051607=PMID:21575908, GO:0032314=GO_REF:0000019, GO:0030838=GO_REF:0000024, GO:0071356=PMID:12486103, GO:0006508=GO_REF:0000002, GO:0070374=PMID:21487011, GO:0032688=PMID:19158675, GO:2000484=PMID:16982856, GO:0090197=PMID:21487011, GO:0043124=PMID:12486103, GO:0032729=GO_REF:0000024, GO:0032760=PMID:21487011, GO:0010803=PMID:14730312, GO:0008656=PMID:12019269, GO:0033209=PMID:12656673, GO:0043280=PMID:15030775, GO:0042771=PMID:14730312, GO:0072332=PMID:14730312, GO:0045087=Reactome:REACT_6802, GO:0050870=PMID:22732093, GO:0002230=GO_REF:0000019, GO:0071347=PMID:12486103, GO:0002277=GO_REF:0000024, GO:0097169=PMID:19158676, GO:0032090=PMID:15030775, GO:2001238=PMID:16964285, GO:2001181=PMID:16982856, GO:0071901=PMID:12486103, GO:0005783=GO_REF:0000039, GO:0008385=PMID:12656673, GO:0005634=GO_REF:0000024, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_75855, GO:0005739=PMID:14730312, GO:0042104=GO_REF:0000024, GO:0051091=PMID:19494289, GO:0005737=PMID:15030775, GO:0050766=GO_REF:0000024, GO:0006954=GO_REF:0000019, GO:0051092=PMID:12656673, GO:0031647=GO_REF:0000024, GO:0002588=GO_REF:0000024, GO:0050718=PMID:15030775, GO:2000778=PMID:16982856, GO:0090200=PMID:14730312, GO:2001242=PMID:14730312, GO:0002821=PMID:22732093, GO:0001773=PMID:22732093, GO:0072559=PMID:15030775, GO:2000406=GO_REF:0000024, GO:0043065=PMID:12646168, GO:0006919=PMID:12019269, GO:0072558=PMID:12191486, GO:0005576=GO_REF:0000019, GO:0032088=PMID:16585594, GO:0006917=PMID:10567338, GO:0004197=GO_REF:0000002, GO:0044444=PMID:19158679, GO:0007165=PMID:12019269, GO:0050829=PMID:21487011, GO:0071222=PMID:12486103, GO:0044351=GO_REF:0000024, GO:0032611=GO_REF:0000019} Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD protein 20130415 {GO:0005515=IPI, GO:0032755=ISS, GO:2001056=IDA, GO:0046330=IMP, GO:0002218=IDA, GO:0042803=IDA, GO:0051607=IDA, GO:0032314=IEA, GO:0030838=ISS, GO:0071356=IDA, GO:0006508=IEA, GO:0070374=IMP, GO:0032688=IMP, GO:2000484=IMP, GO:0090197=IMP, GO:0043124=IDA, GO:0032729=ISS, GO:0032760=IMP, GO:0010803=IMP, GO:0008656=NAS, GO:0033209=IDA, GO:0043280=IDA, GO:0042771=IMP, GO:0072332=IMP, GO:0045087=TAS, GO:0050870=IMP, GO:0002230=IEA, GO:0071347=IDA, GO:0002277=ISS, GO:0097169=IDA, GO:0032090=IPI, GO:2001238=IDA, GO:2001181=IMP, GO:0071901=IDA, GO:0005783=IEA, GO:0008385=TAS, GO:0005634=ISS, GO:0035872=TAS, GO:0005829=TAS, GO:0005739=IDA, GO:0042104=ISS, GO:0051091=IDA, GO:0005737=IDA, GO:0050766=ISS, GO:0006954=IEA, GO:0051092=IDA, GO:0031647=ISS, GO:0002588=ISS, GO:0050718=IDA, GO:2000778=IMP, GO:0090200=IDA, GO:2001242=IDA, GO:0002821=IMP, GO:0001773=IMP, GO:0072559=IDA, GO:2000406=ISS, GO:0043065=IDA, GO:0006919=NAS, GO:0072558=IDA, GO:0005576=IEA, GO:0032088=IMP, GO:0006917=TAS, GO:0004197=IEA, GO:0044444=IDA, GO:0007165=NAS, GO:0050829=IMP, GO:0071222=IDA, GO:0044351=ISS, GO:0032611=IEA} activation of cysteine-type endopeptidase activity involved in apoptotic process, activation of innate immune response, cellular response to interleukin-1, cellular response to lipopolysaccharide, cellular response to tumor necrosis factor, defense response to Gram-negative bacterium, defense response to virus, induction of apoptosis, inflammatory response, innate immune response, interleukin-1 beta production, intrinsic apoptotic signaling pathway by p53 class mediator, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, macropinocytosis, myeloid dendritic cell activation, myeloid dendritic cell activation involved in immune response, negative regulation of I-kappaB kinase/NF-kappaB cascade, negative regulation of NF-kappaB transcription factor activity, negative regulation of interferon-beta production, negative regulation of protein serine/threonine kinase activity, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, positive regulation of ERK1 and ERK2 cascade, positive regulation of JNK cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of T cell activation, positive regulation of T cell migration, positive regulation of actin filament polymerization, positive regulation of activated T cell proliferation, positive regulation of adaptive immune response, positive regulation of antigen processing and presentation of peptide antigen via MHC class II, positive regulation of apoptotic process, positive regulation of chemokine secretion, positive regulation of cysteine-type endopeptidase activity, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of defense response to virus by host, positive regulation of extrinsic apoptotic signaling pathway, positive regulation of interferon-gamma production, positive regulation of interleukin-1 beta secretion, positive regulation of interleukin-10 secretion, positive regulation of interleukin-6 production, positive regulation of interleukin-6 secretion, positive regulation of interleukin-8 secretion, positive regulation of phagocytosis, positive regulation of release of cytochrome c from mitochondria, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of tumor necrosis factor production, proteolysis, regulation of Rac GTPase activity, regulation of intrinsic apoptotic signaling pathway, regulation of protein stability, regulation of tumor necrosis factor-mediated signaling pathway, signal transduction, tumor necrosis factor-mediated signaling pathway AIM2 inflammasome complex, IkappaB kinase complex, NLRP1 inflammasome complex, NLRP3 inflammasome complex, cytoplasm, cytoplasmic part, cytosol, endoplasmic reticulum, extracellular region, mitochondrion, nucleus Pyrin domain binding, cysteine-type endopeptidase activator activity involved in apoptotic process, cysteine-type endopeptidase activity, protein binding, protein homodimerization activity Human UniProtKB:O14862 PYCR1 IntAct UniProtKB {GO:0005739=PMID:19648921, GO:0034641=Reactome:REACT_13, GO:0005759=Reactome:REACT_119, GO:0055129=GO_REF:0000041, GO:0008652=Reactome:REACT_238, GO:0006561=PMID:16730026, GO:0044281=Reactome:REACT_111217, GO:0034599=PMID:19648921, GO:0042802=PMID:16730026, GO:0004735=Reactome:REACT_119} P32322 Pyrroline-5-carboxylate reductase 1, mitochondrial protein 20130415 {GO:0005739=IDA, GO:0034641=TAS, GO:0005759=TAS, GO:0055129=IEA, GO:0008652=TAS, GO:0006561=IDA, GO:0044281=TAS, GO:0034599=IMP, GO:0042802=IPI, GO:0004735=TAS} L-proline biosynthetic process, cellular amino acid biosynthetic process, cellular nitrogen compound metabolic process, cellular response to oxidative stress, proline biosynthetic process, small molecule metabolic process mitochondrial matrix, mitochondrion identical protein binding, pyrroline-5-carboxylate reductase activity Human UniProtKB:P32322 PYCR2 UniPathway UniProtKB {GO:0005737=GO_REF:0000039, GO:0055129=GO_REF:0000041, GO:0004735=GO_REF:0000003} Q96C36 Pyrroline-5-carboxylate reductase 2 protein 20130413 {GO:0005737=IEA, GO:0055129=IEA, GO:0004735=IEA} L-proline biosynthetic process cytoplasm pyrroline-5-carboxylate reductase activity Human UniPathway:UPA00098 PYCRL UniPathway UniProtKB {GO:0055129=GO_REF:0000041, GO:0006561=GO_REF:0000002, GO:0042802=GO_REF:0000019, GO:0004735=GO_REF:0000003} Q53H96 Pyrroline-5-carboxylate reductase 3 protein 20130413 {GO:0055129=IEA, GO:0006561=IEA, GO:0042802=IEA, GO:0004735=IEA} L-proline biosynthetic process, proline biosynthetic process identical protein binding, pyrroline-5-carboxylate reductase activity Human UniPathway:UPA00098 PYDC1 HGNC UniProtKB {GO:0005515=PMID:12656673, GO:0004197=GO_REF:0000002, GO:0050718=PMID:12656673, GO:0045087=PMID:12656673, GO:0008385=PMID:12656673, GO:0006508=GO_REF:0000002, GO:0032088=PMID:12656673, GO:0005634=PMID:12656673, GO:0006469=PMID:12656673, GO:0033209=PMID:12656673, GO:0005829=PMID:12656673} Q8WXC3 Pyrin domain-containing protein 1 protein 20071022 {GO:0005515=IPI, GO:0004197=IEA, GO:0050718=IDA, GO:0045087=IDA, GO:0008385=IDA, GO:0006508=IEA, GO:0032088=IDA, GO:0005634=IDA, GO:0006469=IDA, GO:0033209=IDA, GO:0005829=IDA} innate immune response, negative regulation of NF-kappaB transcription factor activity, negative regulation of protein kinase activity, positive regulation of interleukin-1 beta secretion, proteolysis, tumor necrosis factor-mediated signaling pathway IkappaB kinase complex, cytosol, nucleus cysteine-type endopeptidase activity, protein binding Human PYDC2 IntAct UniProtKB {GO:0005515=PMID:17178784, GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039} Q56P42 Pyrin domain-containing protein 2 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0005634=IEA} cytoplasm, nucleus protein binding Human UniProtKB:Q9ULZ3 PYGB Reactome UniProtKB {GO:0005737=PMID:10638593, GO:0005975=Reactome:REACT_474, GO:0030170=GO_REF:0000002, GO:0006006=Reactome:REACT_723, GO:0008184=PMID:3346228, GO:0044281=Reactome:REACT_111217, GO:0005980=Reactome:REACT_1008} P11216 Glycogen phosphorylase, brain form protein 20130213 {GO:0005737=IDA, GO:0005975=TAS, GO:0030170=IEA, GO:0006006=TAS, GO:0008184=NAS, GO:0044281=TAS, GO:0005980=TAS} carbohydrate metabolic process, glucose metabolic process, glycogen catabolic process, small molecule metabolic process cytoplasm glycogen phosphorylase activity, pyridoxal phosphate binding Human PYGL HPA UniProtKB {GO:0032052=PMID:12204691, GO:0005886=GO_REF:0000052, GO:0016208=PMID:10980448, GO:0005975=Reactome:REACT_474, GO:0005977=PMID:10980448, GO:0008184=Reactome:REACT_21313, GO:0019842=PMID:12204691, GO:0044281=Reactome:REACT_111217, GO:0042593=PMID:17705025, GO:0005524=PMID:10949035, GO:0042803=PMID:17705025, GO:0005536=PMID:12204691, GO:0005829=Reactome:REACT_21313, GO:0005737=GO_REF:0000052, GO:0008144=PMID:10980448, GO:0030170=GO_REF:0000002, GO:0006006=Reactome:REACT_723, GO:0006015=GO_REF:0000019, GO:0002060=PMID:12204691, GO:0005980=Reactome:REACT_1008} P06737 Glycogen phosphorylase, liver form protein 20101115 {GO:0032052=IDA, GO:0005886=IDA, GO:0016208=IDA, GO:0005975=TAS, GO:0005977=IMP, GO:0008184=EXP, GO:0019842=IDA, GO:0044281=TAS, GO:0042593=IMP, GO:0005524=IDA, GO:0042803=NAS, GO:0005536=NAS, GO:0005829=TAS, GO:0005737=IDA, GO:0008144=IDA, GO:0030170=IEA, GO:0006006=TAS, GO:0006015=IEA, GO:0002060=IDA, GO:0005980=TAS} 5-phosphoribose 1-diphosphate biosynthetic process, carbohydrate metabolic process, glucose homeostasis, glucose metabolic process, glycogen catabolic process, glycogen metabolic process, small molecule metabolic process cytoplasm, cytosol, plasma membrane AMP binding, ATP binding, bile acid binding, drug binding, glucose binding, glycogen phosphorylase activity, protein homodimerization activity, purine nucleobase binding, pyridoxal phosphate binding, vitamin binding Human PYGM Reactome UniProtKB {GO:0000166=GO_REF:0000037, GO:0005975=Reactome:REACT_474, GO:0005977=PMID:9633816, GO:0030170=GO_REF:0000002, GO:0006006=Reactome:REACT_723, GO:0008184=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0005980=Reactome:REACT_1008, GO:0005829=Reactome:REACT_21397} P11217 Glycogen phosphorylase, muscle form protein 20130213 {GO:0000166=IEA, GO:0005975=TAS, GO:0005977=TAS, GO:0030170=IEA, GO:0006006=TAS, GO:0008184=IEA, GO:0044281=TAS, GO:0005980=TAS, GO:0005829=TAS} carbohydrate metabolic process, glucose metabolic process, glycogen catabolic process, glycogen metabolic process, small molecule metabolic process cytosol glycogen phosphorylase activity, nucleotide binding, pyridoxal phosphate binding Human PYGO1 IntAct UniProtKB {GO:0005515=PMID:18498752, GO:0034504=GO_REF:0000019, GO:0001822=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0016055=GO_REF:0000019, GO:0009791=GO_REF:0000019} Q9Y3Y4 Pygopus homolog 1 protein 20130415 {GO:0005515=IPI, GO:0034504=IEA, GO:0001822=IEA, GO:0045944=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0016055=IEA, GO:0009791=IEA} Wnt receptor signaling pathway, kidney development, positive regulation of transcription from RNA polymerase II promoter, post-embryonic development, protein localization to nucleus nucleus protein binding, zinc ion binding Human UniProtKB:O00512 PYGO2 UniProtKB UniProtKB {GO:0001822=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0030879=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0033599=GO_REF:0000019, GO:0042393=GO_REF:0000019, GO:0048589=GO_REF:0000019, GO:0002088=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0060070=GO_REF:0000019, GO:0051569=GO_REF:0000019} Q9BRQ0 Pygopus homolog 2 protein 20130413 {GO:0001822=IEA, GO:0005634=IEA, GO:0030879=IEA, GO:0009791=IEA, GO:0001701=IEA, GO:0033599=IEA, GO:0042393=IEA, GO:0048589=IEA, GO:0002088=IEA, GO:0007420=IEA, GO:0060021=IEA, GO:0008270=IEA, GO:0060070=IEA, GO:0051569=IEA} brain development, canonical Wnt receptor signaling pathway, developmental growth, in utero embryonic development, kidney development, lens development in camera-type eye, mammary gland development, palate development, post-embryonic development, regulation of histone H3-K4 methylation, regulation of mammary gland epithelial cell proliferation nucleus histone binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 PYHIN1 UniProtKB UniProtKB {GO:0007049=GO_REF:0000037, GO:0016607=GO_REF:0000039} Q6K0P9 Pyrin and HIN domain-containing protein 1 protein 20130413 {GO:0007049=IEA, GO:0016607=IEA} cell cycle nuclear speck Human UniProtKB-SubCell:SL-0186 PYROXD1 UniProtKB UniProtKB {GO:0016491=GO_REF:0000037} Q8WU10 Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 protein 20130413 {GO:0016491=IEA} oxidoreductase activity Human UniProtKB-KW:KW-0560 PYROXD2 UniProtKB UniProtKB {GO:0016491=GO_REF:0000037} Q8N2H3 Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 protein 20130413 {GO:0016491=IEA} oxidoreductase activity Human UniProtKB-KW:KW-0560 PYY Reactome UniProtKB {GO:0007631=PMID:10698177, GO:0007186=PMID:7592911, GO:0005179=PMID:10698177, GO:0008283=PMID:10488139, GO:0007586=PMID:7493937, GO:0007010=PMID:7493937, GO:0007267=PMID:7493937, GO:0006928=PMID:10488139, GO:0005576=Reactome:REACT_22289, GO:0042755=GO_REF:0000019, GO:0005184=GO_REF:0000019, GO:0005615=GO_REF:0000019} P10082 Peptide YY protein 20081217 {GO:0007631=TAS, GO:0007186=TAS, GO:0005179=TAS, GO:0008283=TAS, GO:0007586=TAS, GO:0007010=TAS, GO:0007267=TAS, GO:0006928=TAS, GO:0005576=TAS, GO:0042755=IEA, GO:0005184=IEA, GO:0005615=IEA} G-protein coupled receptor signaling pathway, cell proliferation, cell-cell signaling, cellular component movement, cytoskeleton organization, digestion, eating behavior, feeding behavior extracellular region, extracellular space hormone activity, neuropeptide hormone activity Human PZP GOC UniProtKB {GO:0010951=PMID:2476433, GO:0007565=PMID:2692707, GO:0004866=PMID:2476433, GO:0004867=GO_REF:0000037, GO:0005576=PMID:14718574, GO:0005615=GO_REF:0000002} P20742 Pregnancy zone protein protein 20130413 {GO:0010951=TAS, GO:0007565=TAS, GO:0004866=TAS, GO:0004867=IEA, GO:0005576=NAS, GO:0005615=IEA} female pregnancy, negative regulation of endopeptidase activity extracellular region, extracellular space endopeptidase inhibitor activity, serine-type endopeptidase inhibitor activity Human QARS HPA UniProtKB {GO:0010467=Reactome:REACT_71, GO:0005737=GO_REF:0000052, GO:0006425=GO_REF:0000002, GO:0005759=Reactome:REACT_15363, GO:0004819=Reactome:REACT_15361, GO:0005524=GO_REF:0000037, GO:0004812=GO_REF:0000002, GO:0005829=Reactome:REACT_15516, GO:0006418=Reactome:REACT_15482} P47897 Glutamine--tRNA ligase protein 20110516 {GO:0010467=TAS, GO:0005737=IDA, GO:0006425=IEA, GO:0005759=TAS, GO:0004819=TAS, GO:0005524=IEA, GO:0004812=IEA, GO:0005829=TAS, GO:0006418=TAS} gene expression, glutaminyl-tRNA aminoacylation, tRNA aminoacylation for protein translation cytoplasm, cytosol, mitochondrial matrix ATP binding, aminoacyl-tRNA ligase activity, glutamine-tRNA ligase activity Human QDPR LIFEdb UniProtKB {GO:0006559=Reactome:REACT_1786, GO:0006520=PMID:3033643, GO:0010288=GO_REF:0000019, GO:0043005=GO_REF:0000019, GO:0051066=PMID:3033643, GO:0006729=GO_REF:0000019, GO:0009055=PMID:3033643, GO:0044281=Reactome:REACT_111217, GO:0070404=GO_REF:0000019, GO:0010044=GO_REF:0000019, GO:0035690=GO_REF:0000019, GO:0070402=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0005829=Reactome:REACT_1925, GO:0001889=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000054, GO:0033762=GO_REF:0000019, GO:0016491=GO_REF:0000002, GO:0004155=Reactome:REACT_1925} P09417 Dihydropteridine reductase protein 20100607 {GO:0006559=TAS, GO:0006520=TAS, GO:0010288=IEA, GO:0043005=IEA, GO:0051066=TAS, GO:0006729=IEA, GO:0009055=TAS, GO:0044281=TAS, GO:0070404=IEA, GO:0010044=IEA, GO:0035690=IEA, GO:0070402=IEA, GO:0042803=IEA, GO:0005829=TAS, GO:0001889=IEA, GO:0005739=IEA, GO:0034641=TAS, GO:0005737=IDA, GO:0033762=IEA, GO:0016491=IEA, GO:0004155=EXP} L-phenylalanine catabolic process, cellular amino acid metabolic process, cellular nitrogen compound metabolic process, cellular response to drug, dihydrobiopterin metabolic process, liver development, response to aluminum ion, response to glucagon stimulus, response to lead ion, small molecule metabolic process, tetrahydrobiopterin biosynthetic process cytoplasm, cytosol, mitochondrion, neuron projection 6,7-dihydropteridine reductase activity, NADH binding, NADPH binding, electron carrier activity, oxidoreductase activity, protein homodimerization activity Human QKI IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0006397=GO_REF:0000037, GO:0008380=GO_REF:0000037, GO:0017124=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0042552=GO_REF:0000019, GO:0007286=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0006417=GO_REF:0000037, GO:0010628=GO_REF:0000019, GO:0042692=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0042759=GO_REF:0000019, GO:0051028=GO_REF:0000037, GO:0001570=GO_REF:0000019} Q96PU8 Protein quaking protein 20130415 {GO:0005515=IPI, GO:0006397=IEA, GO:0008380=IEA, GO:0017124=IEA, GO:0003723=IEA, GO:0042552=IEA, GO:0007286=IEA, GO:0005634=IEA, GO:0006417=IEA, GO:0010628=IEA, GO:0042692=IEA, GO:0005737=IEA, GO:0042759=IEA, GO:0051028=IEA, GO:0001570=IEA} RNA splicing, long-chain fatty acid biosynthetic process, mRNA processing, mRNA transport, muscle cell differentiation, myelination, positive regulation of gene expression, regulation of translation, spermatid development, vasculogenesis cytoplasm, nucleus RNA binding, SH3 domain binding, protein binding Human UniProtKB:Q9NWB1 QPCT PINC UniProtKB {GO:0016603=PMID:21288892, GO:0006508=GO_REF:0000002, GO:0008270=PMID:21288892, GO:0005576=GO_REF:0000039, GO:0008233=GO_REF:0000002, GO:0017186=PMID:21288892, GO:0006464=PMID:7999256} Q16769 Glutaminyl-peptide cyclotransferase protein 20030904 {GO:0016603=IDA, GO:0006508=IEA, GO:0008270=IDA, GO:0005576=IEA, GO:0008233=IEA, GO:0017186=IDA, GO:0006464=TAS} cellular protein modification process, peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase, proteolysis extracellular region glutaminyl-peptide cyclotransferase activity, peptidase activity, zinc ion binding Human QPCTL MGI UniProtKB {GO:0016603=PMID:18486145, GO:0005794=PMID:18486145, GO:0000139=GO_REF:0000039, GO:0006508=GO_REF:0000002, GO:0008270=PMID:21288892, GO:0008233=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0017186=PMID:18486145} Q9NXS2 Glutaminyl-peptide cyclotransferase-like protein protein 20120315 {GO:0016603=IDA, GO:0005794=IDA, GO:0000139=IEA, GO:0006508=IEA, GO:0008270=IDA, GO:0008233=IEA, GO:0016021=IEA, GO:0017186=IDA} peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase, proteolysis Golgi apparatus, Golgi membrane, integral to membrane glutaminyl-peptide cyclotransferase activity, peptidase activity, zinc ion binding Human QPRT Reactome UniProtKB {GO:0006766=Reactome:REACT_11193, GO:0004514=PMID:9473669, GO:0019674=Reactome:REACT_11088, GO:0006767=Reactome:REACT_11238, GO:0044281=Reactome:REACT_111217, GO:0009435=GO_REF:0000041, GO:0051259=PMID:17868694, GO:0042803=PMID:17868694, GO:0034213=PMID:9473669, GO:0005829=Reactome:REACT_11092} Q15274 "Nicotinate-nucleotide pyrophosphorylase ""carboxylating""" protein 20130301 {GO:0006766=TAS, GO:0004514=IDA, GO:0019674=TAS, GO:0006767=TAS, GO:0044281=TAS, GO:0009435=IEA, GO:0051259=IDA, GO:0042803=IDA, GO:0034213=IDA, GO:0005829=TAS} NAD biosynthetic process, NAD metabolic process, protein oligomerization, quinolinate catabolic process, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cytosol nicotinate-nucleotide diphosphorylase (carboxylating) activity, protein homodimerization activity Human QRFP Reactome UniProtKB {GO:0060259=GO_REF:0000024, GO:0007218=PMID:14657341, GO:0031854=GO_REF:0000024, GO:0005576=Reactome:REACT_22436, GO:0007626=GO_REF:0000024, GO:0005575=GO_REF:0000015, GO:0007625=GO_REF:0000019, GO:0045777=GO_REF:0000024, GO:0005184=PMID:14657341} P83859 Orexigenic neuropeptide QRFP protein 20090107 {GO:0060259=ISS, GO:0007218=IDA, GO:0031854=ISS, GO:0005576=TAS, GO:0007626=ISS, GO:0005575=ND, GO:0007625=IEA, GO:0045777=ISS, GO:0005184=IDA} grooming behavior, locomotory behavior, neuropeptide signaling pathway, positive regulation of blood pressure, regulation of feeding behavior cellular_component, extracellular region neuropeptide hormone activity, orexigenic neuropeptide QRFP receptor binding Human QRFPR Reactome UniProtKB {GO:0004983=GO_REF:0000002, GO:0005886=Reactome:REACT_22436, GO:0007186=PMID:12960173, GO:0004930=PMID:12960173, GO:0016021=PMID:12960173} Q96P65 Pyroglutamylated RFamide peptide receptor protein 20090107 {GO:0004983=IEA, GO:0005886=TAS, GO:0007186=IDA, GO:0004930=IDA, GO:0016021=IC} G-protein coupled receptor signaling pathway integral to membrane, plasma membrane G-protein coupled receptor activity, neuropeptide Y receptor activity Human QRICH1 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0042981=GO_REF:0000002, GO:0005575=GO_REF:0000015} Q2TAL8 Glutamine-rich protein 1 protein 20090630 {GO:0005622=IEA, GO:0008150=ND, GO:0003674=ND, GO:0042981=IEA, GO:0005575=ND} biological_process, regulation of apoptotic process cellular_component, intracellular molecular_function Human QRICH2 null null {} null null null null {} null null null QRSL1 UniProtKB UniProtKB {GO:0005739=PMID:19805282, GO:0032543=PMID:19805282, GO:0050567=PMID:19805282, GO:0030956=PMID:19805282, GO:0070681=PMID:19805282, GO:0005524=GO_REF:0000037} Q9H0R6 Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial protein 20110818 {GO:0005739=IDA, GO:0032543=IMP, GO:0050567=IDA, GO:0030956=IDA, GO:0070681=IDA, GO:0005524=IEA} glutaminyl-tRNAGln biosynthesis via transamidation, mitochondrial translation glutamyl-tRNA(Gln) amidotransferase complex, mitochondrion ATP binding, glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity Human QSER1 null null {} null null null null {} null null null QSOX1 GOC UniProtKB {GO:0030173=PMID:17331072, GO:0006457=PMID:18393449, GO:0016971=PMID:18393449, GO:0006662=GO_REF:0000002, GO:0015035=GO_REF:0000002, GO:0003756=PMID:18393449, GO:0009055=GO_REF:0000002, GO:0045454=GO_REF:0000002, GO:0005615=PMID:10708601} O00391 Sulfhydryl oxidase 1 protein 20130413 {GO:0030173=IDA, GO:0006457=IDA, GO:0016971=IDA, GO:0006662=IEA, GO:0015035=IEA, GO:0003756=IDA, GO:0009055=IEA, GO:0045454=IEA, GO:0005615=IDA} cell redox homeostasis, glycerol ether metabolic process, protein folding extracellular space, integral to Golgi membrane electron carrier activity, flavin-linked sulfhydryl oxidase activity, protein disulfide isomerase activity, protein disulfide oxidoreductase activity Human QSOX2 UniProtKB UniProtKB {GO:0031965=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0016972=GO_REF:0000003, GO:0005576=GO_REF:0000039, GO:0045454=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q6ZRP7 Sulfhydryl oxidase 2 protein 20130413 {GO:0031965=IEA, GO:0005886=IEA, GO:0016972=IEA, GO:0005576=IEA, GO:0045454=IEA, GO:0016021=IEA} cell redox homeostasis extracellular region, integral to membrane, nuclear membrane, plasma membrane thiol oxidase activity Human UniProtKB-SubCell:SL-0182 QTRT1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0005840=GO_REF:0000029, GO:0005634=GO_REF:0000039, GO:0006400=PMID:11255023, GO:0046872=GO_REF:0000037, GO:0008479=GO_REF:0000024, GO:0008616=GO_REF:0000024} Q9BXR0 Queuine tRNA-ribosyltransferase protein 20090629 {GO:0005739=IEA, GO:0005840=NAS, GO:0005634=IEA, GO:0006400=TAS, GO:0046872=IEA, GO:0008479=ISS, GO:0008616=ISS} queuosine biosynthetic process, tRNA modification mitochondrion, nucleus, ribosome metal ion binding, queuine tRNA-ribosyltransferase activity Human UniProtKB:Q9JMA2 QTRTD1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0008479=GO_REF:0000024, GO:0008616=GO_REF:0000024} Q9H974 Queuine tRNA-ribosyltransferase subunit QTRTD1 protein 20090811 {GO:0005739=ISS, GO:0005737=ISS, GO:0046872=IEA, GO:0008479=ISS, GO:0008616=ISS} queuosine biosynthetic process cytoplasm, mitochondrion metal ion binding, queuine tRNA-ribosyltransferase activity Human UniProtKB:B8ZXI1 R3HDM1 InterPro UniProtKB {GO:0003676=GO_REF:0000002} Q15032 R3H domain-containing protein 1 protein 20130413 {GO:0003676=IEA} nucleic acid binding Human InterPro:IPR001374 R3HDM2 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002} Q9Y2K5 R3H domain-containing protein 2 protein 20130413 {GO:0005634=IEA, GO:0003676=IEA} nucleus nucleic acid binding Human UniProtKB-SubCell:SL-0191 R3HDM4 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002} Q96D70 R3H domain-containing protein 4 protein 20130413 {GO:0005634=IEA, GO:0003676=IEA} nucleus nucleic acid binding Human UniProtKB-SubCell:SL-0191 R3HDML UniProtKB UniProtKB {GO:0005576=GO_REF:0000039, GO:0030414=GO_REF:0000037} Q9H3Y0 Peptidase inhibitor R3HDML protein 20130413 {GO:0005576=IEA, GO:0030414=IEA} extracellular region peptidase inhibitor activity Human UniProtKB-SubCell:SL-0243 RAB10 GOC UniProtKB {GO:0005802=GO_REF:0000024, GO:0005886=PMID:22908308, GO:0007264=GO_REF:0000002, GO:0043001=GO_REF:0000024, GO:0003924=Reactome:REACT_147836, GO:0007409=GO_REF:0000024, GO:0030859=GO_REF:0000024, GO:0000145=GO_REF:0000024, GO:0097051=PMID:23263280, GO:0016197=PMID:16641372, GO:0030670=GO_REF:0000039, GO:0016192=GO_REF:0000024, GO:0030659=Reactome:REACT_147836, GO:0061467=GO_REF:0000024, GO:0032869=GO_REF:0000024, GO:0005794=PMID:23263280, GO:0071782=PMID:23263280, GO:0071786=PMID:23263280, GO:0045200=GO_REF:0000024, GO:0006893=GO_REF:0000024, GO:0072372=PMID:20576682, GO:0005525=PMID:20937701, GO:0072659=GO_REF:0000024, GO:0006184=Reactome:REACT_147836, GO:0031489=PMID:22908308, GO:0032593=PMID:22908308, GO:0005789=PMID:23263280, GO:0019003=PMID:20937701, GO:0055037=PMID:16641372, GO:0055038=GO_REF:0000039, GO:0016044=Reactome:REACT_11123, GO:0005768=PMID:20576682} P61026 Ras-related protein Rab-10 protein 20130413 {GO:0005802=ISS, GO:0005886=IDA, GO:0007264=IEA, GO:0043001=ISS, GO:0003924=EXP, GO:0007409=ISS, GO:0030859=ISS, GO:0000145=ISS, GO:0097051=IMP, GO:0016197=IMP, GO:0030670=IEA, GO:0016192=ISS, GO:0030659=TAS, GO:0061467=ISS, GO:0032869=ISS, GO:0005794=IDA, GO:0071782=IDA, GO:0071786=IMP, GO:0045200=ISS, GO:0006893=ISS, GO:0072372=IDA, GO:0005525=IDA, GO:0072659=ISS, GO:0006184=EXP, GO:0031489=IPI, GO:0032593=IDA, GO:0005789=IDA, GO:0019003=IDA, GO:0055037=IDA, GO:0055038=IEA, GO:0016044=TAS, GO:0005768=IDA} GTP catabolic process, Golgi to plasma membrane protein transport, Golgi to plasma membrane transport, axonogenesis, basolateral protein localization, cellular membrane organization, cellular response to insulin stimulus, endoplasmic reticulum tubular network organization, endosomal transport, establishment of neuroblast polarity, establishment of protein localization to endoplasmic reticulum membrane, polarized epithelial cell differentiation, protein localization to plasma membrane, small GTPase mediated signal transduction, vesicle-mediated transport Golgi apparatus, cytoplasmic vesicle membrane, endoplasmic reticulum membrane, endoplasmic reticulum tubular network, endosome, exocyst, insulin-responsive compartment, phagocytic vesicle membrane, plasma membrane, primary cilium, recycling endosome, recycling endosome membrane, trans-Golgi network GDP binding, GTP binding, GTPase activity, myosin V binding Human RAB11A IntAct UniProtKB {GO:0005802=PMID:15229288, GO:0030133=GO_REF:0000019, GO:0005515=PMID:17082457, GO:0005886=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0003924=PMID:16905101, GO:0048227=PMID:11163216, GO:0015031=GO_REF:0000037, GO:0032154=PMID:15601896, GO:0031175=PMID:17082457, GO:0032402=GO_REF:0000024, GO:0005739=GO_REF:0000019, GO:0000910=PMID:15601896, GO:0048169=GO_REF:0000019, GO:0030670=GO_REF:0000039, GO:0006833=Reactome:REACT_24023, GO:0016192=PMID:19542231, GO:0030659=Reactome:REACT_23863, GO:0019905=PMID:12145319, GO:0005525=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0072659=PMID:17082457, GO:0051223=GO_REF:0000019, GO:0006184=GO_REF:0000019, GO:0045335=PMID:21255211, GO:0043234=PMID:17462998, GO:0007049=GO_REF:0000037, GO:0055037=GO_REF:0000024, GO:0055038=GO_REF:0000039} P62491 Ras-related protein Rab-11A protein 20130415 {GO:0005802=IDA, GO:0030133=IEA, GO:0005515=IPI, GO:0005886=IEA, GO:0007264=IEA, GO:0003924=IDA, GO:0048227=NAS, GO:0015031=IEA, GO:0032154=IDA, GO:0031175=IMP, GO:0032402=ISS, GO:0005739=IEA, GO:0000910=IMP, GO:0048169=IEA, GO:0030670=IEA, GO:0006833=TAS, GO:0016192=IDA, GO:0030659=TAS, GO:0019905=NAS, GO:0005525=IEA, GO:0055085=TAS, GO:0072659=IDA, GO:0051223=IEA, GO:0006184=IEA, GO:0045335=IDA, GO:0043234=IDA, GO:0007049=IEA, GO:0055037=ISS, GO:0055038=IEA} GTP catabolic process, cell cycle, cytokinesis, melanosome transport, neuron projection development, plasma membrane to endosome transport, protein localization to plasma membrane, protein transport, regulation of long-term neuronal synaptic plasticity, regulation of protein transport, small GTPase mediated signal transduction, transmembrane transport, vesicle-mediated transport, water transport cleavage furrow, cytoplasmic vesicle membrane, mitochondrion, phagocytic vesicle, phagocytic vesicle membrane, plasma membrane, protein complex, recycling endosome, recycling endosome membrane, trans-Golgi network, transport vesicle GTP binding, GTPase activity, protein binding, syntaxin binding Human UniProtKB:Q7L804 RAB11B GOC UniProtKB {GO:0005886=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0003924=PMID:16545962, GO:0015031=GO_REF:0000037, GO:0005525=PMID:16545962, GO:0032402=GO_REF:0000024, GO:0005739=GO_REF:0000019, GO:0045335=PMID:21255211, GO:0006184=PMID:7811277, GO:0007049=GO_REF:0000037, GO:0030670=GO_REF:0000039, GO:0019003=PMID:16545962, GO:0055037=GO_REF:0000024} Q15907 Ras-related protein Rab-11B protein 20130413 {GO:0005886=IEA, GO:0007264=IEA, GO:0003924=IDA, GO:0015031=IEA, GO:0005525=IDA, GO:0032402=ISS, GO:0005739=IEA, GO:0045335=IDA, GO:0006184=TAS, GO:0007049=IEA, GO:0030670=IEA, GO:0019003=IDA, GO:0055037=ISS} GTP catabolic process, cell cycle, melanosome transport, protein transport, small GTPase mediated signal transduction mitochondrion, phagocytic vesicle, phagocytic vesicle membrane, plasma membrane, recycling endosome GDP binding, GTP binding, GTPase activity Human RAB11FIP1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0030670=GO_REF:0000039, GO:0055037=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q6WKZ4 Rab11 family-interacting protein 1 protein 20111111 {GO:0005737=IDA, GO:0030670=IEA, GO:0055037=IEA, GO:0015031=IEA, GO:0043231=IDA} protein transport cytoplasm, intracellular membrane-bounded organelle, phagocytic vesicle membrane, recycling endosome Human RAB11FIP2 HPA UniProtKB {GO:0005515=PMID:17082457, GO:0005886=GO_REF:0000039, GO:0019901=PMID:16775013, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0030010=PMID:16775013, GO:0015031=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0042803=PMID:16905101, GO:0043231=GO_REF:0000052, GO:0006833=Reactome:REACT_24023, GO:0055038=GO_REF:0000039, GO:0030659=Reactome:REACT_23863, GO:0005768=PMID:16905101} Q7L804 Rab11 family-interacting protein 2 protein 20111111 {GO:0005515=IPI, GO:0005886=IEA, GO:0019901=IPI, GO:0005730=IDA, GO:0005634=IDA, GO:0030010=IMP, GO:0015031=IEA, GO:0055085=TAS, GO:0042803=IPI, GO:0043231=IDA, GO:0006833=TAS, GO:0055038=IEA, GO:0030659=TAS, GO:0005768=IDA} establishment of cell polarity, protein transport, transmembrane transport, water transport cytoplasmic vesicle membrane, endosome, intracellular membrane-bounded organelle, nucleolus, nucleus, plasma membrane, recycling endosome membrane protein binding, protein homodimerization activity, protein kinase binding Human RAB11FIP3 HPA UniProtKB {GO:0005515=PMID:16148947, GO:0017137=PMID:18511905, GO:0005813=GO_REF:0000052, GO:0005825=GO_REF:0000052, GO:0030306=PMID:18511905, GO:0005509=GO_REF:0000002, GO:0032456=PMID:17394487, GO:0005730=GO_REF:0000052, GO:0030496=PMID:18511905, GO:0005634=GO_REF:0000052, GO:0032154=PMID:18511905, GO:0042803=PMID:17030804, GO:0043231=GO_REF:0000052, GO:0000910=PMID:16148947, GO:0007049=GO_REF:0000037, GO:0016020=GO_REF:0000019, GO:0055037=PMID:17394487, GO:0016192=PMID:16148947, GO:0055038=GO_REF:0000039, GO:0005768=PMID:16148947} O75154 Rab11 family-interacting protein 3 protein 20120912 {GO:0005515=IPI, GO:0017137=IPI, GO:0005813=IDA, GO:0005825=IDA, GO:0030306=IPI, GO:0005509=IEA, GO:0032456=IDA, GO:0005730=IDA, GO:0030496=IDA, GO:0005634=IDA, GO:0032154=IDA, GO:0042803=IDA, GO:0043231=IDA, GO:0000910=IMP, GO:0007049=IEA, GO:0016020=IEA, GO:0055037=IDA, GO:0016192=TAS, GO:0055038=IEA, GO:0005768=IDA} cell cycle, cytokinesis, endocytic recycling, vesicle-mediated transport centrosome, cleavage furrow, endosome, half bridge of spindle pole body, intracellular membrane-bounded organelle, membrane, midbody, nucleolus, nucleus, recycling endosome, recycling endosome membrane ADP-ribosylation factor binding, Rab GTPase binding, calcium ion binding, protein binding, protein homodimerization activity Human RAB11FIP4 UniProtKB UniProtKB {GO:0005515=PMID:12470645, GO:0017137=PMID:12470645, GO:0030306=PMID:16148947, GO:0005509=GO_REF:0000002, GO:0030496=PMID:15601896, GO:0030139=PMID:20682791, GO:0032154=PMID:15601896, GO:0042803=PMID:12470645, GO:0000910=PMID:16148947, GO:0019048=GO_REF:0000037, GO:0006810=GO_REF:0000037, GO:0055038=PMID:12470645, GO:0005768=PMID:20682791} Q86YS3 Rab11 family-interacting protein 4 protein 20110629 {GO:0005515=IPI, GO:0017137=IPI, GO:0030306=IPI, GO:0005509=IEA, GO:0030496=IDA, GO:0030139=IDA, GO:0032154=IDA, GO:0042803=IDA, GO:0000910=IMP, GO:0019048=IEA, GO:0006810=IEA, GO:0055038=IDA, GO:0005768=IDA} cytokinesis, transport, virus-host interaction cleavage furrow, endocytic vesicle, endosome, midbody, recycling endosome membrane ADP-ribosylation factor binding, Rab GTPase binding, calcium ion binding, protein binding, protein homodimerization activity Human RAB11FIP5 HPA UniProtKB {GO:0005515=PMID:12470645, GO:0008150=GO_REF:0000015, GO:0005813=GO_REF:0000052, GO:0043015=PMID:11278501, GO:0005741=PMID:11278501, GO:0015031=GO_REF:0000037, GO:0055038=GO_REF:0000039, GO:0043231=GO_REF:0000052} Q9BXF6 Rab11 family-interacting protein 5 protein 20110516 {GO:0005515=IPI, GO:0008150=ND, GO:0005813=IDA, GO:0043015=IDA, GO:0005741=IDA, GO:0015031=IEA, GO:0055038=IEA, GO:0043231=IDA} biological_process, protein transport centrosome, intracellular membrane-bounded organelle, mitochondrial outer membrane, recycling endosome membrane gamma-tubulin binding, protein binding Human RAB12 UniProtKB UniProtKB {GO:0000139=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0008333=GO_REF:0000024, GO:0019003=PMID:20937701, GO:0044257=GO_REF:0000024, GO:0005765=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0005525=GO_REF:0000037, GO:0055038=GO_REF:0000024, GO:0005764=GO_REF:0000024} Q6IQ22 Ras-related protein Rab-12 protein 20121219 {GO:0000139=IEA, GO:0007264=IEA, GO:0008333=ISS, GO:0019003=IDA, GO:0044257=ISS, GO:0005765=IEA, GO:0015031=IEA, GO:0005525=IEA, GO:0055038=ISS, GO:0005764=ISS} cellular protein catabolic process, endosome to lysosome transport, protein transport, small GTPase mediated signal transduction Golgi membrane, lysosomal membrane, lysosome, recycling endosome membrane GDP binding, GTP binding Human RAB13 GOC UniProtKB {GO:0005794=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0007264=GO_REF:0000002, GO:0003924=Reactome:REACT_147836, GO:0015031=GO_REF:0000037, GO:0005525=PMID:20937701, GO:0006184=Reactome:REACT_147836, GO:0005737=GO_REF:0000052, GO:0005923=GO_REF:0000039, GO:0007155=PMID:8294494, GO:0016192=PMID:8294494, GO:0016044=Reactome:REACT_11123, GO:0030659=Reactome:REACT_147836} P51153 Ras-related protein Rab-13 protein 20130413 {GO:0005794=IEA, GO:0005886=IDA, GO:0007264=IEA, GO:0003924=EXP, GO:0015031=IEA, GO:0005525=IDA, GO:0006184=EXP, GO:0005737=IDA, GO:0005923=IEA, GO:0007155=TAS, GO:0016192=TAS, GO:0016044=TAS, GO:0030659=TAS} GTP catabolic process, cell adhesion, cellular membrane organization, protein transport, small GTPase mediated signal transduction, vesicle-mediated transport Golgi apparatus, cytoplasm, cytoplasmic vesicle membrane, plasma membrane, tight junction GTP binding, GTPase activity Human RAB14 GOC UniProtKB {GO:0005515=PMID:16034420, GO:0048471=GO_REF:0000024, GO:0005886=GO_REF:0000024, GO:0007264=GO_REF:0000029, GO:0032456=PMID:22595670, GO:0042175=GO_REF:0000024, GO:0003924=Reactome:REACT_147836, GO:0009790=GO_REF:0000024, GO:0015031=GO_REF:0000037, GO:0005764=GO_REF:0000024, GO:0007269=GO_REF:0000029, GO:0005829=GO_REF:0000024, GO:0005622=GO_REF:0000054, GO:0032880=PMID:22595670, GO:0030670=GO_REF:0000039, GO:0016192=PMID:15004230, GO:0030140=GO_REF:0000024, GO:0030659=Reactome:REACT_147836, GO:0005791=GO_REF:0000024, GO:0005795=GO_REF:0000024, GO:0005770=GO_REF:0000024, GO:0046907=PMID:15004230, GO:0005525=PMID:16034420, GO:0006895=GO_REF:0000024, GO:0006184=Reactome:REACT_147836, GO:0045335=PMID:21255211, GO:0000139=GO_REF:0000039, GO:0008543=GO_REF:0000024, GO:0031901=GO_REF:0000039, GO:0055037=PMID:22595670, GO:0019003=PMID:16034420, GO:0016044=Reactome:REACT_11123, GO:0005769=GO_REF:0000024} P61106 Ras-related protein Rab-14 protein 20130413 {GO:0005515=IPI, GO:0048471=ISS, GO:0005886=ISS, GO:0007264=NAS, GO:0032456=IDA, GO:0042175=ISS, GO:0003924=EXP, GO:0009790=ISS, GO:0015031=IEA, GO:0005764=ISS, GO:0007269=NAS, GO:0005829=ISS, GO:0005622=IDA, GO:0032880=IDA, GO:0030670=IEA, GO:0016192=NAS, GO:0030140=ISS, GO:0030659=TAS, GO:0005791=ISS, GO:0005795=ISS, GO:0005770=ISS, GO:0046907=NAS, GO:0005525=IDA, GO:0006895=ISS, GO:0006184=EXP, GO:0045335=IDA, GO:0000139=IEA, GO:0008543=ISS, GO:0031901=IEA, GO:0055037=IDA, GO:0019003=IDA, GO:0016044=TAS, GO:0005769=ISS} GTP catabolic process, Golgi to endosome transport, cellular membrane organization, embryo development, endocytic recycling, fibroblast growth factor receptor signaling pathway, intracellular transport, neurotransmitter secretion, protein transport, regulation of protein localization, small GTPase mediated signal transduction, vesicle-mediated transport Golgi membrane, Golgi stack, cytoplasmic vesicle membrane, cytosol, early endosome, early endosome membrane, intracellular, late endosome, lysosome, nuclear outer membrane-endoplasmic reticulum membrane network, perinuclear region of cytoplasm, phagocytic vesicle, phagocytic vesicle membrane, plasma membrane, recycling endosome, rough endoplasmic reticulum, trans-Golgi network transport vesicle GDP binding, GTP binding, GTPase activity, protein binding Human RAB15 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0015031=GO_REF:0000037} P59190 Ras-related protein Rab-15 protein 20130413 {GO:0005886=IEA, GO:0007264=IEA, GO:0005525=IEA, GO:0015031=IEA} protein transport, small GTPase mediated signal transduction plasma membrane GTP binding Human UniProtKB-SubCell:SL-0039 RAB17 LIFEdb UniProtKB {GO:0042470=GO_REF:0000024, GO:0051963=GO_REF:0000024, GO:0002415=GO_REF:0000024, GO:0007264=GO_REF:0000002, GO:0032456=GO_REF:0000024, GO:0005525=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0030425=GO_REF:0000024, GO:0032402=GO_REF:0000024, GO:0032401=GO_REF:0000024, GO:0005622=GO_REF:0000054, GO:0016323=GO_REF:0000024, GO:0051489=GO_REF:0000024, GO:0016324=GO_REF:0000024, GO:0045056=GO_REF:0000024, GO:0043025=GO_REF:0000024, GO:0050773=GO_REF:0000024, GO:0046847=GO_REF:0000024, GO:0055037=GO_REF:0000024, GO:0019003=PMID:20937701, GO:0055038=GO_REF:0000024} Q9H0T7 Ras-related protein Rab-17 protein 20100607 {GO:0042470=ISS, GO:0051963=ISS, GO:0002415=ISS, GO:0007264=IEA, GO:0032456=ISS, GO:0005525=IEA, GO:0015031=IEA, GO:0030425=ISS, GO:0032402=ISS, GO:0032401=ISS, GO:0005622=IDA, GO:0016323=ISS, GO:0051489=ISS, GO:0016324=ISS, GO:0045056=ISS, GO:0043025=ISS, GO:0050773=ISS, GO:0046847=ISS, GO:0055037=ISS, GO:0019003=IDA, GO:0055038=ISS} endocytic recycling, establishment of melanosome localization, filopodium assembly, immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor, melanosome transport, protein transport, regulation of dendrite development, regulation of filopodium assembly, regulation of synapse assembly, small GTPase mediated signal transduction, transcytosis apical plasma membrane, basolateral plasma membrane, dendrite, intracellular, melanosome, neuronal cell body, recycling endosome, recycling endosome membrane GDP binding, GTP binding Human RAB18 GOC UniProtKB {GO:0006184=PMID:10648831, GO:0005622=GO_REF:0000054, GO:0005886=GO_REF:0000039, GO:0007420=GO_REF:0000024, GO:0007264=PMID:10648831, GO:0001654=GO_REF:0000024, GO:0003924=PMID:10648831, GO:0019003=PMID:20937701, GO:0005525=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0006897=GO_REF:0000029} Q9NP72 Ras-related protein Rab-18 protein 20130413 {GO:0006184=NAS, GO:0005622=IDA, GO:0005886=IEA, GO:0007420=ISS, GO:0007264=NAS, GO:0001654=ISS, GO:0003924=NAS, GO:0019003=IDA, GO:0005525=IEA, GO:0015031=IEA, GO:0006897=NAS} GTP catabolic process, brain development, endocytosis, eye development, protein transport, small GTPase mediated signal transduction intracellular, plasma membrane GDP binding, GTP binding, GTPase activity Human RAB1A GOC UniProtKB {GO:0006184=PMID:2501306, GO:0000139=Reactome:REACT_147881, GO:0000088=Reactome:REACT_765, GO:0005783=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0000087=Reactome:REACT_910, GO:0003924=PMID:2501306, GO:0000278=Reactome:REACT_152, GO:0016192=GO_REF:0000037, GO:0005525=GO_REF:0000037, GO:0015031=GO_REF:0000037} P62820 Ras-related protein Rab-1A protein 20130413 {GO:0006184=TAS, GO:0000139=TAS, GO:0000088=TAS, GO:0005783=IEA, GO:0007264=IEA, GO:0000087=TAS, GO:0003924=TAS, GO:0000278=TAS, GO:0016192=IEA, GO:0005525=IEA, GO:0015031=IEA} GTP catabolic process, M phase of mitotic cell cycle, mitotic cell cycle, mitotic prophase, protein transport, small GTPase mediated signal transduction, vesicle-mediated transport Golgi membrane, endoplasmic reticulum GTP binding, GTPase activity Human RAB1B LIFEdb UniProtKB {GO:0005739=GO_REF:0000019, GO:0005794=GO_REF:0000054, GO:0016020=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0005525=PMID:20937701, GO:0015031=GO_REF:0000037} Q9H0U4 Ras-related protein Rab-1B protein 20100607 {GO:0005739=IEA, GO:0005794=IDA, GO:0016020=IEA, GO:0007264=IEA, GO:0005525=IDA, GO:0015031=IEA} protein transport, small GTPase mediated signal transduction Golgi apparatus, membrane, mitochondrion GTP binding Human RAB20 UniProtKB UniProtKB {GO:0045335=PMID:21255211, GO:0005794=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0030670=GO_REF:0000039, GO:0090383=PMID:21255211, GO:0015031=GO_REF:0000037, GO:0005525=GO_REF:0000037, GO:0090385=PMID:21255211} Q9NX57 Ras-related protein Rab-20 protein 20130108 {GO:0045335=IDA, GO:0005794=IEA, GO:0007264=IEA, GO:0030670=IEA, GO:0090383=IMP, GO:0015031=IEA, GO:0005525=IEA, GO:0090385=IMP} phagosome acidification, phagosome-lysosome fusion, protein transport, small GTPase mediated signal transduction Golgi apparatus, phagocytic vesicle, phagocytic vesicle membrane GTP binding Human RAB21 GOC UniProtKB {GO:0005515=PMID:17450153, GO:0007264=GO_REF:0000002, GO:0003924=PMID:16034420, GO:0015031=GO_REF:0000037, GO:0005525=PMID:16034420, GO:0032154=GO_REF:0000039, GO:0006184=PMID:16034420, GO:0000139=GO_REF:0000039, GO:0031901=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0019003=PMID:20937701, GO:0030659=GO_REF:0000039, GO:0005768=GO_REF:0000054} Q9UL25 Ras-related protein Rab-21 protein 20130413 {GO:0005515=IPI, GO:0007264=IEA, GO:0003924=IDA, GO:0015031=IEA, GO:0005525=IDA, GO:0032154=IEA, GO:0006184=IDA, GO:0000139=IEA, GO:0031901=IEA, GO:0005789=IEA, GO:0019003=IDA, GO:0030659=IEA, GO:0005768=IDA} GTP catabolic process, protein transport, small GTPase mediated signal transduction Golgi membrane, cleavage furrow, cytoplasmic vesicle membrane, early endosome membrane, endoplasmic reticulum membrane, endosome GDP binding, GTP binding, GTPase activity, protein binding Human RAB22A IntAct UniProtKB {GO:0005515=PMID:11870209, GO:0005886=PMID:11870209, GO:0007264=GO_REF:0000002, GO:0003924=PMID:11870209, GO:0015031=GO_REF:0000037, GO:0005525=GO_REF:0000019, GO:0015629=GO_REF:0000019, GO:0001726=GO_REF:0000039, GO:0006897=PMID:11870209, GO:0045335=PMID:21255211, GO:0030670=GO_REF:0000039, GO:0007032=PMID:11870209, GO:0019003=PMID:20937701, GO:0010008=GO_REF:0000039, GO:0005769=PMID:11870209} Q9UL26 Ras-related protein Rab-22A protein 20130415 {GO:0005515=IPI, GO:0005886=IDA, GO:0007264=IEA, GO:0003924=TAS, GO:0015031=IEA, GO:0005525=IEA, GO:0015629=IEA, GO:0001726=IEA, GO:0006897=IDA, GO:0045335=IDA, GO:0030670=IEA, GO:0007032=IEP, GO:0019003=IDA, GO:0010008=IEA, GO:0005769=IDA} endocytosis, endosome organization, protein transport, small GTPase mediated signal transduction actin cytoskeleton, early endosome, endosome membrane, phagocytic vesicle, phagocytic vesicle membrane, plasma membrane, ruffle GDP binding, GTP binding, GTPase activity, protein binding Human UniProtKB:Q15075 RAB23 UniProtKB UniProtKB {GO:0021513=GO_REF:0000019, GO:0005776=PMID:22452336, GO:0005886=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0003924=PMID:22365972, GO:0005525=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0042992=PMID:22365972, GO:0045861=GO_REF:0000019, GO:0045335=PMID:21255211, GO:0006184=PMID:22365972, GO:0006968=PMID:22452336, GO:0005737=PMID:22365972, GO:0008589=GO_REF:0000019, GO:0030670=GO_REF:0000039, GO:0000045=PMID:22452336, GO:0097094=PMID:17503333, GO:0042733=GO_REF:0000019, GO:0010008=GO_REF:0000039} Q9ULC3 Ras-related protein Rab-23 protein 20130108 {GO:0021513=IEA, GO:0005776=IDA, GO:0005886=IEA, GO:0007264=IEA, GO:0003924=IDA, GO:0005525=IEA, GO:0015031=IEA, GO:0042992=IMP, GO:0045861=IEA, GO:0045335=IDA, GO:0006184=IDA, GO:0006968=IMP, GO:0005737=IDA, GO:0008589=IEA, GO:0030670=IEA, GO:0000045=IMP, GO:0097094=IMP, GO:0042733=IEA, GO:0010008=IEA} GTP catabolic process, autophagic vacuole assembly, cellular defense response, craniofacial suture morphogenesis, embryonic digit morphogenesis, negative regulation of proteolysis, negative regulation of transcription factor import into nucleus, protein transport, regulation of smoothened signaling pathway, small GTPase mediated signal transduction, spinal cord dorsal/ventral patterning autophagic vacuole, cytoplasm, endosome membrane, phagocytic vesicle, phagocytic vesicle membrane, plasma membrane GTP binding, GTPase activity Human RAB24 UniProtKB UniProtKB {GO:0005515=PMID:16034420, GO:0005739=GO_REF:0000019, GO:0005776=GO_REF:0000019, GO:0016020=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0006914=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0005525=GO_REF:0000037, GO:0005829=GO_REF:0000039} Q969Q5 Ras-related protein Rab-24 protein 20091119 {GO:0005515=IPI, GO:0005739=IEA, GO:0005776=IEA, GO:0016020=IEA, GO:0007264=IEA, GO:0006914=IEA, GO:0015031=IEA, GO:0005525=IEA, GO:0005829=IEA} autophagy, protein transport, small GTPase mediated signal transduction autophagic vacuole, cytosol, membrane, mitochondrion GTP binding, protein binding Human UniProtKB:Q9H1K0 RAB25 UniProtKB UniProtKB {GO:0005515=PMID:17925226, GO:0008284=PMID:15502842, GO:0031268=PMID:17925226, GO:0007264=GO_REF:0000002, GO:0016023=GO_REF:0000039, GO:0031410=PMID:17925226, GO:0031260=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0005525=GO_REF:0000037, GO:0031143=PMID:17925226} P57735 Ras-related protein Rab-25 protein 20100517 {GO:0005515=IPI, GO:0008284=IDA, GO:0031268=IDA, GO:0007264=IEA, GO:0016023=IEA, GO:0031410=IDA, GO:0031260=IEA, GO:0015031=IEA, GO:0005525=IEA, GO:0031143=IDA} positive regulation of cell proliferation, protein transport, pseudopodium organization, small GTPase mediated signal transduction cytoplasmic membrane-bounded vesicle, cytoplasmic vesicle, pseudopodium, pseudopodium membrane GTP binding, protein binding Human UniProtKB:P05556 RAB26 UniProtKB UniProtKB {GO:0007264=GO_REF:0000002, GO:0043001=PMID:23105096, GO:0031226=GO_REF:0000024, GO:0015031=GO_REF:0000002, GO:0005525=PMID:23105096, GO:0008150=GO_REF:0000015, GO:0045055=PMID:20038531, GO:0000139=PMID:23105096, GO:0017157=GO_REF:0000024, GO:0035272=PMID:20038531, GO:0019002=PMID:23105096, GO:0030658=GO_REF:0000039, GO:0030667=GO_REF:0000024} Q9ULW5 Ras-related protein Rab-26 protein 20130104 {GO:0007264=IEA, GO:0043001=IMP, GO:0031226=ISS, GO:0015031=IEA, GO:0005525=IMP, GO:0008150=ND, GO:0045055=IMP, GO:0000139=IDA, GO:0017157=ISS, GO:0035272=IMP, GO:0019002=IMP, GO:0030658=IEA, GO:0030667=ISS} Golgi to plasma membrane protein transport, biological_process, exocrine system development, protein transport, regulated secretory pathway, regulation of exocytosis, small GTPase mediated signal transduction Golgi membrane, intrinsic to plasma membrane, secretory granule membrane, transport vesicle membrane GMP binding, GTP binding Human RAB27A Reactome UniProtKB {GO:0005515=PMID:18266782, GO:0043316=GO_REF:0000019, GO:0007264=GO_REF:0000002, GO:0003924=GO_REF:0000024, GO:0006605=GO_REF:0000019, GO:0006887=PMID:18812475, GO:0005764=PMID:15548590, GO:0032402=GO_REF:0000019, GO:0030425=PMID:11266474, GO:0045921=PMID:19966785, GO:0016324=GO_REF:0000019, GO:0071985=PMID:19966785, GO:0042470=PMID:11266474, GO:0005794=GO_REF:0000019, GO:0043320=GO_REF:0000019, GO:0005770=PMID:17237785, GO:0019904=GO_REF:0000019, GO:0032585=PMID:19966785, GO:0030318=GO_REF:0000019, GO:0005525=GO_REF:0000024, GO:0031489=GO_REF:0000019, GO:0007596=GO_REF:0000019, GO:0019003=PMID:20937701, GO:0044267=Reactome:REACT_17015, GO:0070382=PMID:18812475, GO:0030667=GO_REF:0000019, GO:0001750=GO_REF:0000019} P51159 Ras-related protein Rab-27A protein 20130301 {GO:0005515=IPI, GO:0043316=IEA, GO:0007264=IEA, GO:0003924=ISS, GO:0006605=IEA, GO:0006887=IDA, GO:0005764=IDA, GO:0032402=IEA, GO:0030425=IDA, GO:0045921=IMP, GO:0016324=IEA, GO:0071985=IMP, GO:0042470=IDA, GO:0005794=IEA, GO:0043320=IEA, GO:0005770=IDA, GO:0019904=IEA, GO:0032585=IDA, GO:0030318=IEA, GO:0005525=ISS, GO:0031489=IEA, GO:0007596=IEA, GO:0019003=IDA, GO:0044267=TAS, GO:0070382=IDA, GO:0030667=IEA, GO:0001750=IEA} blood coagulation, cellular protein metabolic process, cytotoxic T cell degranulation, exocytosis, melanocyte differentiation, melanosome transport, multivesicular body sorting pathway, natural killer cell degranulation, positive regulation of exocytosis, protein targeting, small GTPase mediated signal transduction Golgi apparatus, apical plasma membrane, dendrite, exocytic vesicle, late endosome, lysosome, melanosome, multivesicular body membrane, photoreceptor outer segment, secretory granule membrane GDP binding, GTP binding, GTPase activity, myosin V binding, protein binding, protein domain specific binding Human RAB27B UniProtKB UniProtKB {GO:0005795=PMID:19966785, GO:0007264=GO_REF:0000002, GO:0019904=PMID:16880209, GO:0003924=GO_REF:0000024, GO:0032585=PMID:19966785, GO:0005525=GO_REF:0000024, GO:0015031=GO_REF:0000002, GO:0045921=PMID:19966785, GO:0016324=GO_REF:0000019, GO:0042589=GO_REF:0000019, GO:0071985=PMID:19966785, GO:0019003=PMID:20937701, GO:0030140=PMID:19966785} O00194 Ras-related protein Rab-27B protein 20091119 {GO:0005795=IDA, GO:0007264=IEA, GO:0019904=IPI, GO:0003924=ISS, GO:0032585=IDA, GO:0005525=ISS, GO:0015031=IEA, GO:0045921=IMP, GO:0016324=IEA, GO:0042589=IEA, GO:0071985=IMP, GO:0019003=IDA, GO:0030140=IDA} multivesicular body sorting pathway, positive regulation of exocytosis, protein transport, small GTPase mediated signal transduction Golgi stack, apical plasma membrane, multivesicular body membrane, trans-Golgi network transport vesicle, zymogen granule membrane GDP binding, GTP binding, GTPase activity, protein domain specific binding Human UniProtKB:Q99P58 RAB28 UniProtKB UniProtKB {GO:0006184=PMID:8647132, GO:0005886=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0003924=PMID:8647132, GO:0019003=PMID:20937701, GO:0005525=GO_REF:0000038} Q8WVF3 RAB28 protein protein 20130413 {GO:0006184=TAS, GO:0005886=IEA, GO:0007264=IEA, GO:0003924=TAS, GO:0019003=IDA, GO:0005525=IEA} GTP catabolic process, small GTPase mediated signal transduction plasma membrane GDP binding, GTP binding, GTPase activity Human UniProtKB-KW:KW-0342 RAB2A GOC UniProtKB {GO:0042470=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0003924=PMID:16034420, GO:0015031=GO_REF:0000037, GO:0005525=PMID:16034420, GO:0006184=PMID:2501306, GO:0006888=PMID:8910601, GO:0000088=Reactome:REACT_765, GO:0000139=Reactome:REACT_147850, GO:0033116=GO_REF:0000039, GO:0000087=Reactome:REACT_910, GO:0005789=GO_REF:0000039, GO:0019003=PMID:16034420, GO:0000278=Reactome:REACT_152} P61019 Ras-related protein Rab-2A protein 20130413 {GO:0042470=IEA, GO:0007264=IEA, GO:0003924=IDA, GO:0015031=IEA, GO:0005525=IDA, GO:0006184=TAS, GO:0006888=TAS, GO:0000088=TAS, GO:0000139=TAS, GO:0033116=IEA, GO:0000087=TAS, GO:0005789=IEA, GO:0019003=IDA, GO:0000278=TAS} ER to Golgi vesicle-mediated transport, GTP catabolic process, M phase of mitotic cell cycle, mitotic cell cycle, mitotic prophase, protein transport, small GTPase mediated signal transduction Golgi membrane, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment membrane, melanosome GDP binding, GTP binding, GTPase activity Human RAB2B UniProtKB UniProtKB {GO:0045921=PMID:19966785, GO:0005886=GO_REF:0000039, GO:0000139=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0016192=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0005525=GO_REF:0000037} Q8WUD1 Ras-related protein Rab-2B protein 20110803 {GO:0045921=IMP, GO:0005886=IEA, GO:0000139=IEA, GO:0007264=IEA, GO:0005789=IEA, GO:0016192=IEA, GO:0015031=IEA, GO:0005525=IEA} positive regulation of exocytosis, protein transport, small GTPase mediated signal transduction, vesicle-mediated transport Golgi membrane, endoplasmic reticulum membrane, plasma membrane GTP binding Human RAB30 GOC UniProtKB {GO:0006184=PMID:9792283, GO:0005802=PMID:22188167, GO:0005801=PMID:22188167, GO:0005795=PMID:9792283, GO:0016020=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0003924=PMID:9792283, GO:0031985=PMID:22188167, GO:0007030=PMID:22188167, GO:0015031=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q15771 Ras-related protein Rab-30 protein 20130413 {GO:0006184=TAS, GO:0005802=IDA, GO:0005801=IDA, GO:0005795=TAS, GO:0016020=IEA, GO:0007264=IEA, GO:0003924=TAS, GO:0031985=IDA, GO:0007030=IMP, GO:0015031=IEA, GO:0005525=IEA} GTP catabolic process, Golgi organization, protein transport, small GTPase mediated signal transduction Golgi cisterna, Golgi stack, cis-Golgi network, membrane, trans-Golgi network GTP binding, GTPase activity Human RAB31 GOC UniProtKB {GO:0032869=PMID:17189207, GO:0005794=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0043001=PMID:17678623, GO:0003924=PMID:8863739, GO:0005525=PMID:17189207, GO:0032588=PMID:17678623, GO:0006184=PMID:8863739, GO:0031623=PMID:19725050, GO:0045335=PMID:21255211, GO:0045055=PMID:17189207, GO:0030670=GO_REF:0000039, GO:0019003=PMID:17189207, GO:0090382=PMID:21255211, GO:0005769=PMID:17189207} Q13636 Ras-related protein Rab-31 protein 20130413 {GO:0032869=IMP, GO:0005794=IEA, GO:0007264=IEA, GO:0043001=IMP, GO:0003924=TAS, GO:0005525=IDA, GO:0032588=IDA, GO:0006184=TAS, GO:0031623=IMP, GO:0045335=IDA, GO:0045055=IMP, GO:0030670=IEA, GO:0019003=IDA, GO:0090382=IMP, GO:0005769=IDA} GTP catabolic process, Golgi to plasma membrane protein transport, cellular response to insulin stimulus, phagosome maturation, receptor internalization, regulated secretory pathway, small GTPase mediated signal transduction Golgi apparatus, early endosome, phagocytic vesicle, phagocytic vesicle membrane, trans-Golgi network membrane GDP binding, GTP binding, GTPase activity Human RAB32 UniProtKB UniProtKB {GO:0045335=PMID:21255211, GO:0005739=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0030670=GO_REF:0000039, GO:0005525=GO_REF:0000037, GO:0015031=GO_REF:0000002, GO:0090382=PMID:21255211} Q13637 Ras-related protein Rab-32 protein 20130108 {GO:0045335=IDA, GO:0005739=IEA, GO:0007264=IEA, GO:0030670=IEA, GO:0005525=IEA, GO:0015031=IEA, GO:0090382=IMP} phagosome maturation, protein transport, small GTPase mediated signal transduction mitochondrion, phagocytic vesicle, phagocytic vesicle membrane GTP binding Human RAB33A GOC UniProtKB {GO:0006184=PMID:7688322, GO:0005515=PMID:19060904, GO:0005886=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0003924=PMID:7688322, GO:0005525=GO_REF:0000037, GO:0015031=GO_REF:0000002} Q14088 Ras-related protein Rab-33A protein 20130413 {GO:0006184=TAS, GO:0005515=IPI, GO:0005886=IEA, GO:0007264=IEA, GO:0003924=TAS, GO:0005525=IEA, GO:0015031=IEA} GTP catabolic process, protein transport, small GTPase mediated signal transduction plasma membrane GTP binding, GTPase activity, protein binding Human RAB33B LIFEdb UniProtKB {GO:0005794=GO_REF:0000054, GO:0000139=GO_REF:0000039, GO:0005796=PMID:18448665, GO:0007264=GO_REF:0000002, GO:2000156=PMID:20163571, GO:2000785=GO_REF:0000024, GO:0006914=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0005525=GO_REF:0000037} Q9H082 Ras-related protein Rab-33B protein 20100607 {GO:0005794=IDA, GO:0000139=IEA, GO:0005796=IDA, GO:0007264=IEA, GO:2000156=IMP, GO:2000785=ISS, GO:0006914=IEA, GO:0015031=IEA, GO:0005525=IEA} autophagy, protein transport, regulation of autophagic vacuole assembly, regulation of retrograde vesicle-mediated transport, Golgi to ER, small GTPase mediated signal transduction Golgi apparatus, Golgi lumen, Golgi membrane GTP binding Human RAB34 UniProtKB UniProtKB {GO:0005794=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0003924=GO_REF:0000019, GO:0005730=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0005525=GO_REF:0000037, GO:0001726=GO_REF:0000019, GO:0006897=GO_REF:0000019, GO:0045335=PMID:21255211, GO:0030670=GO_REF:0000039, GO:0090382=PMID:21255211, GO:0005769=GO_REF:0000019, GO:0090385=PMID:21255211} Q9BZG1 Ras-related protein Rab-34 protein 20130108 {GO:0005794=IEA, GO:0007264=IEA, GO:0003924=IEA, GO:0005730=IEA, GO:0015031=IEA, GO:0005525=IEA, GO:0001726=IEA, GO:0006897=IEA, GO:0045335=IDA, GO:0030670=IEA, GO:0090382=IMP, GO:0005769=IEA, GO:0090385=IMP} endocytosis, phagosome maturation, phagosome-lysosome fusion, protein transport, small GTPase mediated signal transduction Golgi apparatus, early endosome, nucleolus, phagocytic vesicle, phagocytic vesicle membrane, ruffle GTP binding, GTPase activity Human RAB35 GOC UniProtKB {GO:0042470=GO_REF:0000039, GO:0031253=PMID:16950109, GO:0005886=PMID:16950109, GO:0007264=GO_REF:0000002, GO:0003924=PMID:7811277, GO:0005546=PMID:16950109, GO:0015031=GO_REF:0000037, GO:0005525=PMID:20937701, GO:0045171=PMID:16950109, GO:0006184=PMID:7811277, GO:0005739=GO_REF:0000019, GO:0000910=PMID:16950109, GO:0005905=PMID:16950109, GO:0045334=PMID:16950109, GO:0008104=PMID:16950109, GO:0016197=PMID:16950109, GO:0019003=PMID:20937701, GO:0005768=GO_REF:0000039} Q15286 Ras-related protein Rab-35 protein 20130413 {GO:0042470=IEA, GO:0031253=IDA, GO:0005886=IDA, GO:0007264=IEA, GO:0003924=TAS, GO:0005546=IDA, GO:0015031=IEA, GO:0005525=IDA, GO:0045171=IDA, GO:0006184=TAS, GO:0005739=IEA, GO:0000910=IMP, GO:0005905=IDA, GO:0045334=IDA, GO:0008104=IMP, GO:0016197=IMP, GO:0019003=IDA, GO:0005768=IEA} GTP catabolic process, cytokinesis, endosomal transport, protein localization, protein transport, small GTPase mediated signal transduction cell projection membrane, clathrin-coated endocytic vesicle, coated pit, endosome, intercellular bridge, melanosome, mitochondrion, plasma membrane GDP binding, GTP binding, GTPase activity, phosphatidylinositol-4,5-bisphosphate binding Human RAB36 PINC UniProtKB {GO:0005794=PMID:9920784, GO:0000139=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0015031=GO_REF:0000037, GO:0005525=GO_REF:0000037} O95755 Ras-related protein Rab-36 protein 20030904 {GO:0005794=TAS, GO:0000139=IEA, GO:0007264=IEA, GO:0015031=IEA, GO:0005525=IEA} protein transport, small GTPase mediated signal transduction Golgi apparatus, Golgi membrane GTP binding Human RAB37 UniProtKB UniProtKB {GO:0005793=PMID:15308636, GO:0007264=GO_REF:0000002, GO:0030141=GO_REF:0000019, GO:0005525=GO_REF:0000037, GO:0015031=GO_REF:0000037} Q96AX2 Ras-related protein Rab-37 protein 20060116 {GO:0005793=IDA, GO:0007264=IEA, GO:0030141=IEA, GO:0005525=IEA, GO:0015031=IEA} protein transport, small GTPase mediated signal transduction endoplasmic reticulum-Golgi intermediate compartment, secretory granule GTP binding Human RAB38 GOC UniProtKB {GO:0006184=PMID:10910072, GO:0045335=PMID:21255211, GO:0042470=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0007264=PMID:10910072, GO:0003924=PMID:10910072, GO:0030670=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0090383=PMID:21255211, GO:0015031=PMID:10910072, GO:0005525=PMID:10910072} P57729 Ras-related protein Rab-38 protein 20130413 {GO:0006184=NAS, GO:0045335=IDA, GO:0042470=IEA, GO:0005886=IEA, GO:0007264=NAS, GO:0003924=NAS, GO:0030670=IEA, GO:0005575=ND, GO:0090383=IMP, GO:0015031=NAS, GO:0005525=NAS} GTP catabolic process, phagosome acidification, protein transport, small GTPase mediated signal transduction cellular_component, melanosome, phagocytic vesicle, phagocytic vesicle membrane, plasma membrane GTP binding, GTPase activity Human RAB39A UniProtKB UniProtKB {GO:0045335=PMID:21255211, GO:0008150=GO_REF:0000015, GO:0005886=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0030670=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0090383=PMID:21255211, GO:0005525=PMID:9119394, GO:0015031=GO_REF:0000037, GO:0090385=PMID:21255211} Q14964 Ras-related protein Rab-39A protein 20130108 {GO:0045335=IDA, GO:0008150=ND, GO:0005886=IEA, GO:0007264=IEA, GO:0030670=IEA, GO:0005575=ND, GO:0090383=IMP, GO:0005525=NAS, GO:0015031=IEA, GO:0090385=IMP} biological_process, phagosome acidification, phagosome-lysosome fusion, protein transport, small GTPase mediated signal transduction cellular_component, phagocytic vesicle, phagocytic vesicle membrane, plasma membrane GTP binding Human RAB39B LIFEdb UniProtKB {GO:0005622=GO_REF:0000054, GO:0005794=PMID:20159109, GO:0050808=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0016192=GO_REF:0000024, GO:0015031=GO_REF:0000037, GO:0005525=GO_REF:0000037} Q96DA2 Ras-related protein Rab-39B protein 20100607 {GO:0005622=IDA, GO:0005794=IDA, GO:0050808=ISS, GO:0005886=IEA, GO:0007264=IEA, GO:0016192=ISS, GO:0015031=IEA, GO:0005525=IEA} protein transport, small GTPase mediated signal transduction, synapse organization, vesicle-mediated transport Golgi apparatus, intracellular, plasma membrane GTP binding Human RAB3A GOC UniProtKB {GO:0060201=Reactome:REACT_15483, GO:0005515=PMID:10859313, GO:0070083=Reactome:REACT_15533, GO:0005886=Reactome:REACT_23813, GO:0048790=GO_REF:0000019, GO:0007264=GO_REF:0000002, GO:0030324=GO_REF:0000019, GO:0003924=PMID:10859313, GO:0007268=Reactome:REACT_13685, GO:0007409=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0060203=Reactome:REACT_12617, GO:0007269=Reactome:REACT_13723, GO:0005829=GO_REF:0000019, GO:0003016=GO_REF:0000019, GO:0051602=GO_REF:0000019, GO:0051117=GO_REF:0000019, GO:0001669=GO_REF:0000019, GO:0007274=GO_REF:0000019, GO:0008022=GO_REF:0000019, GO:0005525=GO_REF:0000019, GO:0014047=Reactome:REACT_12591, GO:0016079=GO_REF:0000019, GO:0008021=GO_REF:0000019, GO:0006184=PMID:2501306, GO:0043234=GO_REF:0000019, GO:0051020=GO_REF:0000019, GO:0031630=GO_REF:0000019, GO:0016188=GO_REF:0000019, GO:0050975=GO_REF:0000019, GO:0061202=Reactome:REACT_23973, GO:0007005=GO_REF:0000019, GO:0001671=GO_REF:0000019} P20336 Ras-related protein Rab-3A protein 20130413 {GO:0060201=TAS, GO:0005515=IPI, GO:0070083=TAS, GO:0005886=TAS, GO:0048790=IEA, GO:0007264=IEA, GO:0030324=IEA, GO:0003924=IMP, GO:0007268=TAS, GO:0007409=IEA, GO:0009791=IEA, GO:0015031=IEA, GO:0060203=TAS, GO:0007269=TAS, GO:0005829=IEA, GO:0003016=IEA, GO:0051602=IEA, GO:0051117=IEA, GO:0001669=IEA, GO:0007274=IEA, GO:0008022=IEA, GO:0005525=IEA, GO:0014047=TAS, GO:0016079=IEA, GO:0008021=IEA, GO:0006184=TAS, GO:0043234=IEA, GO:0051020=IEA, GO:0031630=IEA, GO:0016188=IEA, GO:0050975=IEA, GO:0061202=TAS, GO:0007005=IEA, GO:0001671=IEA} GTP catabolic process, axonogenesis, glutamate secretion, lung development, maintenance of presynaptic active zone structure, mitochondrion organization, neuromuscular synaptic transmission, neurotransmitter secretion, post-embryonic development, protein transport, regulation of synaptic vesicle fusion to presynaptic membrane, respiratory system process, response to electrical stimulus, sensory perception of touch, small GTPase mediated signal transduction, synaptic transmission, synaptic vesicle exocytosis, synaptic vesicle maturation acrosomal vesicle, clathrin-sculpted acetylcholine transport vesicle membrane, clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane, clathrin-sculpted glutamate transport vesicle membrane, clathrin-sculpted monoamine transport vesicle membrane, cytosol, plasma membrane, protein complex, synaptic vesicle ATPase activator activity, ATPase binding, GTP binding, GTPase activity, GTPase binding, protein C-terminus binding, protein binding Human RAB3B GOC UniProtKB {GO:0006184=PMID:2501306, GO:0018125=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0017157=GO_REF:0000019, GO:0003924=PMID:2501306, GO:0030141=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0005525=GO_REF:0000037, GO:0008021=GO_REF:0000019, GO:0005829=GO_REF:0000019} P20337 Ras-related protein Rab-3B protein 20130413 {GO:0006184=TAS, GO:0018125=IEA, GO:0005886=IEA, GO:0007264=IEA, GO:0017157=IEA, GO:0003924=TAS, GO:0030141=IEA, GO:0015031=IEA, GO:0005525=IEA, GO:0008021=IEA, GO:0005829=IEA} GTP catabolic process, peptidyl-cysteine methylation, protein transport, regulation of exocytosis, small GTPase mediated signal transduction cytosol, plasma membrane, secretory granule, synaptic vesicle GTP binding, GTPase activity Human RAB3C UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0017157=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0005525=GO_REF:0000037, GO:0008021=GO_REF:0000019, GO:0005829=GO_REF:0000019} Q96E17 Ras-related protein Rab-3C protein 20130413 {GO:0005886=IEA, GO:0007264=IEA, GO:0017157=IEA, GO:0015031=IEA, GO:0005525=IEA, GO:0008021=IEA, GO:0005829=IEA} protein transport, regulation of exocytosis, small GTPase mediated signal transduction cytosol, plasma membrane, synaptic vesicle GTP binding Human UniProtKB-SubCell:SL-0039 RAB3D GOC UniProtKB {GO:0030133=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0003924=PMID:10023084, GO:0005525=GO_REF:0000037, GO:0006887=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0005739=GO_REF:0000019, GO:0042588=GO_REF:0000019, GO:0006184=PMID:10023084, GO:0018125=GO_REF:0000019, GO:0051020=GO_REF:0000019, GO:0017157=GO_REF:0000019} O95716 Ras-related protein Rab-3D protein 20130413 {GO:0030133=IEA, GO:0005886=IEA, GO:0007264=IEA, GO:0003924=TAS, GO:0005525=IEA, GO:0006887=IEA, GO:0015031=IEA, GO:0005739=IEA, GO:0042588=IEA, GO:0006184=TAS, GO:0018125=IEA, GO:0051020=IEA, GO:0017157=IEA} GTP catabolic process, exocytosis, peptidyl-cysteine methylation, protein transport, regulation of exocytosis, small GTPase mediated signal transduction mitochondrion, plasma membrane, transport vesicle, zymogen granule GTP binding, GTPase activity, GTPase binding Human RAB3GAP1 GOC UniProtKB {GO:0017137=PMID:10859313, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0060325=PMID:20512159, GO:0007420=PMID:20512159, GO:0005730=GO_REF:0000052, GO:0032851=PMID:9030515, GO:0043010=PMID:20512159, GO:0005634=GO_REF:0000052, GO:0021854=PMID:20512159, GO:0043087=PMID:10859313, GO:0005097=PMID:16923123} Q15042 Rab3 GTPase-activating protein catalytic subunit protein 20130413 {GO:0017137=IPI, GO:0005813=IDA, GO:0005737=IDA, GO:0060325=IMP, GO:0007420=IMP, GO:0005730=IDA, GO:0032851=IDA, GO:0043010=IMP, GO:0005634=IDA, GO:0021854=IMP, GO:0043087=IDA, GO:0005097=IDA} brain development, camera-type eye development, face morphogenesis, hypothalamus development, positive regulation of Rab GTPase activity, regulation of GTPase activity centrosome, cytoplasm, nucleolus, nucleus Rab GTPase activator activity, Rab GTPase binding Human RAB3GAP2 GOC UniProtKB {GO:0043547=PMID:9733780, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0046982=GO_REF:0000024, GO:0030234=GO_REF:0000024, GO:0043085=PMID:9733780, GO:0008047=PMID:9733780, GO:0006886=PMID:9733780, GO:0043087=GO_REF:0000024, GO:0005096=GO_REF:0000037} Q9H2M9 Rab3 GTPase-activating protein non-catalytic subunit protein 20130413 {GO:0043547=TAS, GO:0005737=IDA, GO:0005886=IDA, GO:0046982=ISS, GO:0030234=ISS, GO:0043085=TAS, GO:0008047=TAS, GO:0006886=TAS, GO:0043087=ISS, GO:0005096=IEA} intracellular protein transport, positive regulation of GTPase activity, positive regulation of catalytic activity, regulation of GTPase activity cytoplasm, plasma membrane GTPase activator activity, enzyme activator activity, enzyme regulator activity, protein heterodimerization activity Human RAB3IL1 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0017112=PMID:20937701, GO:0015031=GO_REF:0000037} Q8TBN0 Guanine nucleotide exchange factor for Rab-3A protein 20130415 {GO:0005515=IPI, GO:0017112=IDA, GO:0015031=IEA} protein transport Rab guanyl-nucleotide exchange factor activity, protein binding Human UniProtKB:Q96QF0 RAB3IP IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0017112=PMID:20937701, GO:0005634=PMID:12007189, GO:0005856=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0030027=GO_REF:0000039, GO:0005829=PMID:12007189} Q96QF0 Rab-3A-interacting protein protein 20130415 {GO:0005515=IPI, GO:0017112=IDA, GO:0005634=IDA, GO:0005856=IEA, GO:0015031=IEA, GO:0030027=IEA, GO:0005829=IDA} protein transport cytoskeleton, cytosol, lamellipodium, nucleus Rab guanyl-nucleotide exchange factor activity, protein binding Human UniProtKB:Q8TBN0 RAB40A UniPathway UniProtKB {GO:0016567=GO_REF:0000041, GO:0005886=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0015031=GO_REF:0000002} Q8WXH6 Ras-related protein Rab-40A protein 20130413 {GO:0016567=IEA, GO:0005886=IEA, GO:0007264=IEA, GO:0005525=IEA, GO:0015031=IEA} protein transport, protein ubiquitination, small GTPase mediated signal transduction plasma membrane GTP binding Human UniPathway:UPA00143 RAB40AL UniProtKB UniProtKB {GO:0005739=PMID:22581972, GO:0005737=PMID:22581972, GO:0016567=GO_REF:0000041, GO:0005886=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0015031=GO_REF:0000002} P0C0E4 Ras-related protein Rab-40A-like protein 20130214 {GO:0005739=IDA, GO:0005737=IDA, GO:0016567=IEA, GO:0005886=IEA, GO:0007264=IEA, GO:0005525=IEA, GO:0015031=IEA} protein transport, protein ubiquitination, small GTPase mediated signal transduction cytoplasm, mitochondrion, plasma membrane GTP binding Human RAB40B UniPathway UniProtKB {GO:0035556=GO_REF:0000002, GO:0016567=GO_REF:0000041, GO:0005886=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0015031=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q12829 Ras-related protein Rab-40B protein 20130413 {GO:0035556=IEA, GO:0016567=IEA, GO:0005886=IEA, GO:0007264=IEA, GO:0015031=IEA, GO:0005525=IEA} intracellular signal transduction, protein transport, protein ubiquitination, small GTPase mediated signal transduction plasma membrane GTP binding Human UniPathway:UPA00143 RAB40C UniPathway UniProtKB {GO:0048471=GO_REF:0000019, GO:0016567=GO_REF:0000041, GO:0005886=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0019003=GO_REF:0000019, GO:0005525=GO_REF:0000019, GO:0015031=GO_REF:0000002} Q96S21 Ras-related protein Rab-40C protein 20130413 {GO:0048471=IEA, GO:0016567=IEA, GO:0005886=IEA, GO:0007264=IEA, GO:0019003=IEA, GO:0005525=IEA, GO:0015031=IEA} protein transport, protein ubiquitination, small GTPase mediated signal transduction perinuclear region of cytoplasm, plasma membrane GDP binding, GTP binding Human UniPathway:UPA00143 RAB43 GOC UniProtKB {GO:0006184=PMID:17562788, GO:0045335=PMID:21255211, GO:0035526=PMID:17562788, GO:0005794=PMID:17562788, GO:0007264=GO_REF:0000002, GO:0003924=PMID:17562788, GO:0007030=PMID:17684057, GO:0030670=GO_REF:0000039, GO:0015031=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0090382=PMID:21255211} Q86YS6 Ras-related protein Rab-43 protein 20130413 {GO:0006184=IDA, GO:0045335=IDA, GO:0035526=IMP, GO:0005794=IDA, GO:0007264=IEA, GO:0003924=IDA, GO:0007030=IMP, GO:0030670=IEA, GO:0015031=IEA, GO:0005525=IEA, GO:0090382=IMP} GTP catabolic process, Golgi organization, phagosome maturation, protein transport, retrograde transport, plasma membrane to Golgi, small GTPase mediated signal transduction Golgi apparatus, phagocytic vesicle, phagocytic vesicle membrane GTP binding, GTPase activity Human RAB4A GOC UniProtKB {GO:0006184=PMID:2501306, GO:0005515=PMID:19570034, GO:0016020=GO_REF:0000039, GO:0030100=GO_REF:0000019, GO:0007264=GO_REF:0000002, GO:0008565=GO_REF:0000019, GO:0003924=PMID:15907487, GO:0005525=PMID:16034420, GO:0019003=PMID:16034420, GO:0016044=Reactome:REACT_11123, GO:0005768=GO_REF:0000019} P20338 Ras-related protein Rab-4A protein 20130413 {GO:0006184=TAS, GO:0005515=IPI, GO:0016020=IEA, GO:0030100=IEA, GO:0007264=IEA, GO:0008565=IEA, GO:0003924=IDA, GO:0005525=IDA, GO:0019003=IDA, GO:0016044=TAS, GO:0005768=IEA} GTP catabolic process, cellular membrane organization, regulation of endocytosis, small GTPase mediated signal transduction endosome, membrane GDP binding, GTP binding, GTPase activity, protein binding, protein transporter activity Human RAB4B UniProtKB UniProtKB {GO:0006184=GO_REF:0000029, GO:0005622=GO_REF:0000029, GO:0005886=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0003924=GO_REF:0000029, GO:0016192=GO_REF:0000029, GO:0015031=GO_REF:0000037, GO:0005525=GO_REF:0000038} Q6PIK3 Ras-related protein Rab-4B protein 20130413 {GO:0006184=NAS, GO:0005622=NAS, GO:0005886=IEA, GO:0007264=IEA, GO:0003924=NAS, GO:0016192=NAS, GO:0015031=IEA, GO:0005525=IEA} GTP catabolic process, protein transport, small GTPase mediated signal transduction, vesicle-mediated transport intracellular, plasma membrane GTP binding, GTPase activity Human UniProtKB-KW:KW-0342 RAB5A GOC UniProtKB {GO:0005515=PMID:15377662, GO:0042470=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0003924=PMID:15378032, GO:0030139=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0005525=PMID:15378032, GO:0015629=GO_REF:0000019, GO:0001726=GO_REF:0000039, GO:0030154=GO_REF:0000037, GO:0006897=PMID:15378032, GO:0007399=GO_REF:0000037, GO:0006184=PMID:2501306, GO:0045921=PMID:19966785, GO:0051489=PMID:14978216, GO:0007596=Reactome:REACT_604, GO:0031901=GO_REF:0000039, GO:0045121=GO_REF:0000019, GO:0019003=PMID:15378032, GO:0010008=Reactome:REACT_24949, GO:0005769=PMID:15078902, GO:2000286=PMID:16890161} P20339 Ras-related protein Rab-5A protein 20130413 {GO:0005515=IPI, GO:0042470=IEA, GO:0005886=IEA, GO:0007264=IEA, GO:0003924=IDA, GO:0030139=IEA, GO:0015031=IEA, GO:0005525=IDA, GO:0015629=IEA, GO:0001726=IEA, GO:0030154=IEA, GO:0006897=IDA, GO:0007399=IEA, GO:0006184=TAS, GO:0045921=IMP, GO:0051489=IDA, GO:0007596=TAS, GO:0031901=IEA, GO:0045121=IEA, GO:0019003=IDA, GO:0010008=TAS, GO:0005769=IDA, GO:2000286=IMP} GTP catabolic process, blood coagulation, cell differentiation, endocytosis, nervous system development, positive regulation of exocytosis, protein transport, receptor internalization involved in canonical Wnt receptor signaling pathway, regulation of filopodium assembly, small GTPase mediated signal transduction actin cytoskeleton, early endosome, early endosome membrane, endocytic vesicle, endosome membrane, melanosome, membrane raft, plasma membrane, ruffle GDP binding, GTP binding, GTPase activity, protein binding Human RAB5B GOC UniProtKB {GO:0005515=PMID:10491193, GO:0042470=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0003924=PMID:1541686, GO:0030139=GO_REF:0000019, GO:0005525=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0006184=PMID:1541686, GO:0005622=GO_REF:0000054, GO:0030742=PMID:10491193, GO:0016020=PMID:1541686, GO:0030100=GO_REF:0000019, GO:0031901=GO_REF:0000039, GO:0007032=GO_REF:0000019, GO:0019003=PMID:20937701, GO:0005768=PMID:10491193} P61020 Ras-related protein Rab-5B protein 20130413 {GO:0005515=IPI, GO:0042470=IEA, GO:0005886=IEA, GO:0007264=IEA, GO:0003924=TAS, GO:0030139=IEA, GO:0005525=IEA, GO:0015031=IEA, GO:0006184=TAS, GO:0005622=IDA, GO:0030742=IDA, GO:0016020=TAS, GO:0030100=IEA, GO:0031901=IEA, GO:0007032=IEA, GO:0019003=IDA, GO:0005768=IDA} GTP catabolic process, endosome organization, protein transport, regulation of endocytosis, small GTPase mediated signal transduction early endosome membrane, endocytic vesicle, endosome, intracellular, melanosome, membrane, plasma membrane GDP binding, GTP binding, GTP-dependent protein binding, GTPase activity, protein binding Human RAB5C GOC UniProtKB {GO:0006184=PMID:8646882, GO:0042470=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0030100=GO_REF:0000019, GO:0007264=GO_REF:0000002, GO:0031901=GO_REF:0000039, GO:0003924=PMID:8646882, GO:0030139=GO_REF:0000019, GO:0007032=GO_REF:0000019, GO:0019003=PMID:20937701, GO:0015031=GO_REF:0000037, GO:0005525=GO_REF:0000037} P51148 Ras-related protein Rab-5C protein 20130413 {GO:0006184=TAS, GO:0042470=IEA, GO:0005886=IEA, GO:0030100=IEA, GO:0007264=IEA, GO:0031901=IEA, GO:0003924=TAS, GO:0030139=IEA, GO:0007032=IEA, GO:0019003=IDA, GO:0015031=IEA, GO:0005525=IEA} GTP catabolic process, endosome organization, protein transport, regulation of endocytosis, small GTPase mediated signal transduction early endosome membrane, endocytic vesicle, melanosome, plasma membrane GDP binding, GTP binding, GTPase activity Human RAB6A GOC UniProtKB {GO:0005515=PMID:18243103, GO:0005802=PMID:12447383, GO:0005794=PMID:15229288, GO:0007264=GO_REF:0000002, GO:0006890=PMID:12447383, GO:0019904=PMID:12447383, GO:0003924=PMID:18243103, GO:0072385=PMID:12447383, GO:0031410=PMID:12447383, GO:0005525=PMID:19141279, GO:0015031=GO_REF:0000002, GO:0005829=PMID:12447383, GO:0006184=PMID:2501306, GO:0018125=PMID:11121396, GO:0016020=PMID:12447383, GO:0000139=GO_REF:0000039, GO:0034067=PMID:12447383, GO:0000042=PMID:18243103} P20340 Ras-related protein Rab-6A protein 20130413 {GO:0005515=IPI, GO:0005802=IDA, GO:0005794=IDA, GO:0007264=IEA, GO:0006890=TAS, GO:0019904=IPI, GO:0003924=IDA, GO:0072385=TAS, GO:0031410=IDA, GO:0005525=IDA, GO:0015031=IEA, GO:0005829=IDA, GO:0006184=TAS, GO:0018125=IDA, GO:0016020=IDA, GO:0000139=IEA, GO:0034067=IDA, GO:0000042=IDA} GTP catabolic process, minus-end-directed organelle transport along microtubule, peptidyl-cysteine methylation, protein localization to Golgi apparatus, protein targeting to Golgi, protein transport, retrograde vesicle-mediated transport, Golgi to ER, small GTPase mediated signal transduction Golgi apparatus, Golgi membrane, cytoplasmic vesicle, cytosol, membrane, trans-Golgi network GTP binding, GTPase activity, protein binding, protein domain specific binding Human RAB6B GOC UniProtKB {GO:0006184=PMID:10893188, GO:0005794=PMID:10893188, GO:0000139=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0006890=PMID:10893188, GO:0003924=PMID:10893188, GO:0016023=GO_REF:0000039, GO:0005525=GO_REF:0000037, GO:0015031=GO_REF:0000037} Q9NRW1 Ras-related protein Rab-6B protein 20130413 {GO:0006184=NAS, GO:0005794=NAS, GO:0000139=IEA, GO:0007264=IEA, GO:0006890=NAS, GO:0003924=NAS, GO:0016023=IEA, GO:0005525=IEA, GO:0015031=IEA} GTP catabolic process, protein transport, retrograde vesicle-mediated transport, Golgi to ER, small GTPase mediated signal transduction Golgi apparatus, Golgi membrane, cytoplasmic membrane-bounded vesicle GTP binding, GTPase activity Human RAB6C GOC UniProtKB {GO:0006184=PMID:10455022, GO:0005622=PMID:10455022, GO:0005813=PMID:20064528, GO:0005737=GO_REF:0000039, GO:0007264=PMID:10455022, GO:0042493=PMID:11054569, GO:0003924=PMID:10455022, GO:0005634=GO_REF:0000039, GO:0010824=PMID:20064528, GO:0022402=PMID:20064528, GO:0005525=GO_REF:0000037, GO:0015031=GO_REF:0000002} Q9H0N0 Ras-related protein Rab-6C protein 20130413 {GO:0006184=IDA, GO:0005622=IC, GO:0005813=IDA, GO:0005737=IEA, GO:0007264=TAS, GO:0042493=IDA, GO:0003924=IDA, GO:0005634=IEA, GO:0010824=IMP, GO:0022402=IMP, GO:0005525=IEA, GO:0015031=IEA} GTP catabolic process, cell cycle process, protein transport, regulation of centrosome duplication, response to drug, small GTPase mediated signal transduction centrosome, cytoplasm, intracellular, nucleus GTP binding, GTPase activity Human RAB7A GOC UniProtKB {GO:0005515=PMID:18272684, GO:0097208=GO_REF:0000019, GO:0007264=GO_REF:0000002, GO:0045453=GO_REF:0000019, GO:0003924=PMID:18272684, GO:0045022=PMID:14617358, GO:0015031=PMID:19392663, GO:0005765=Reactome:REACT_120995, GO:0005764=PMID:18272684, GO:0043231=GO_REF:0000052, GO:0019886=Reactome:REACT_121399, GO:0007174=PMID:18272684, GO:0030670=GO_REF:0000039, GO:0090383=PMID:21255211, GO:0090382=PMID:19392663, GO:0090385=PMID:21255211, GO:0042470=GO_REF:0000039, GO:0005794=GO_REF:0000052, GO:0005770=PMID:18272684, GO:0008333=PMID:18272684, GO:0005525=PMID:18272684, GO:0006897=PMID:2115402, GO:0006184=PMID:8954989, GO:0045335=PMID:21255211, GO:0048365=GO_REF:0000019, GO:0019003=PMID:18272684} P51149 Ras-related protein Rab-7a protein 20130413 {GO:0005515=IPI, GO:0097208=IEA, GO:0007264=IEA, GO:0045453=IEA, GO:0003924=IDA, GO:0045022=IMP, GO:0015031=TAS, GO:0005765=TAS, GO:0005764=IDA, GO:0043231=IDA, GO:0019886=TAS, GO:0007174=IMP, GO:0030670=IEA, GO:0090383=IMP, GO:0090382=TAS, GO:0090385=IMP, GO:0042470=IEA, GO:0005794=IDA, GO:0005770=IDA, GO:0008333=IMP, GO:0005525=IDA, GO:0006897=TAS, GO:0006184=TAS, GO:0045335=IDA, GO:0048365=IEA, GO:0019003=IDA} GTP catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class II, bone resorption, early endosome to late endosome transport, endocytosis, endosome to lysosome transport, epidermal growth factor catabolic process, phagosome acidification, phagosome maturation, phagosome-lysosome fusion, protein transport, small GTPase mediated signal transduction Golgi apparatus, alveolar lamellar body, intracellular membrane-bounded organelle, late endosome, lysosomal membrane, lysosome, melanosome, phagocytic vesicle, phagocytic vesicle membrane GDP binding, GTP binding, GTPase activity, Rac GTPase binding, protein binding Human RAB7B UniProtKB UniProtKB {GO:0005802=PMID:20375062, GO:0032755=PMID:20953574, GO:0034144=GO_REF:0000024, GO:0005794=PMID:20375062, GO:0007264=GO_REF:0000002, GO:0005770=PMID:20375062, GO:0005525=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0005764=PMID:20375062, GO:0045335=PMID:21255211, GO:0045654=PMID:20953574, GO:0051092=PMID:20953574, GO:0034499=PMID:20375062, GO:0030670=GO_REF:0000039, GO:0034164=GO_REF:0000024} Q96AH8 Ras-related protein Rab-7b protein 20130108 {GO:0005802=IDA, GO:0032755=IMP, GO:0034144=ISS, GO:0005794=IDA, GO:0007264=IEA, GO:0005770=IDA, GO:0005525=IEA, GO:0015031=IEA, GO:0005764=IDA, GO:0045335=IDA, GO:0045654=IMP, GO:0051092=IMP, GO:0034499=IMP, GO:0030670=IEA, GO:0034164=ISS} late endosome to Golgi transport, negative regulation of toll-like receptor 4 signaling pathway, negative regulation of toll-like receptor 9 signaling pathway, positive regulation of NF-kappaB transcription factor activity, positive regulation of interleukin-6 production, positive regulation of megakaryocyte differentiation, protein transport, small GTPase mediated signal transduction Golgi apparatus, late endosome, lysosome, phagocytic vesicle, phagocytic vesicle membrane, trans-Golgi network GTP binding Human RAB7L1 GOC UniProtKB {GO:0006184=PMID:9284931, GO:0005886=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0003924=PMID:9284931, GO:0015031=GO_REF:0000037, GO:0005525=GO_REF:0000037} O14966 Ras-related protein Rab-7L1 protein 20130413 {GO:0006184=TAS, GO:0005886=IEA, GO:0007264=IEA, GO:0003924=TAS, GO:0015031=IEA, GO:0005525=IEA} GTP catabolic process, protein transport, small GTPase mediated signal transduction plasma membrane GTP binding, GTPase activity Human RAB8A GOC UniProtKB {GO:0005515=PMID:20643351, GO:0048471=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0003924=Reactome:REACT_147836, GO:0007409=GO_REF:0000024, GO:0015031=GO_REF:0000037, GO:0006904=PMID:17574030, GO:0048210=PMID:17574030, GO:0000086=Reactome:REACT_2203, GO:0048169=GO_REF:0000019, GO:0030670=GO_REF:0000039, GO:0043025=GO_REF:0000019, GO:0005932=GO_REF:0000019, GO:0030659=Reactome:REACT_147836, GO:0017137=GO_REF:0000024, GO:0019901=GO_REF:0000019, GO:0014069=GO_REF:0000019, GO:0031513=PMID:17574030, GO:0005525=PMID:20937701, GO:0051223=GO_REF:0000019, GO:0006184=Reactome:REACT_147836, GO:0045335=PMID:21255211, GO:0042384=PMID:17574030, GO:0000139=Reactome:REACT_160293, GO:0019003=PMID:20937701, GO:0000278=Reactome:REACT_152, GO:0055037=GO_REF:0000019, GO:0016044=Reactome:REACT_11123} P61006 Ras-related protein Rab-8A protein 20130413 {GO:0005515=IPI, GO:0048471=IEA, GO:0005886=IEA, GO:0007264=IEA, GO:0003924=EXP, GO:0007409=ISS, GO:0015031=IEA, GO:0006904=IDA, GO:0048210=IDA, GO:0000086=TAS, GO:0048169=IEA, GO:0030670=IEA, GO:0043025=IEA, GO:0005932=IEA, GO:0030659=TAS, GO:0017137=ISS, GO:0019901=IEA, GO:0014069=IEA, GO:0031513=IDA, GO:0005525=IDA, GO:0051223=IEA, GO:0006184=EXP, GO:0045335=IDA, GO:0042384=IDA, GO:0000139=TAS, GO:0019003=IDA, GO:0000278=TAS, GO:0055037=IEA, GO:0016044=TAS} G2/M transition of mitotic cell cycle, GTP catabolic process, Golgi vesicle fusion to target membrane, axonogenesis, cellular membrane organization, cilium assembly, mitotic cell cycle, protein transport, regulation of long-term neuronal synaptic plasticity, regulation of protein transport, small GTPase mediated signal transduction, vesicle docking involved in exocytosis Golgi membrane, cytoplasmic vesicle membrane, microtubule basal body, neuronal cell body, nonmotile primary cilium, perinuclear region of cytoplasm, phagocytic vesicle, phagocytic vesicle membrane, plasma membrane, postsynaptic density, recycling endosome GDP binding, GTP binding, GTPase activity, Rab GTPase binding, protein binding, protein kinase binding Human RAB8B GOC UniProtKB {GO:0030911=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0005102=PMID:18346465, GO:0003924=PMID:9030196, GO:0005575=GO_REF:0000015, GO:0015031=GO_REF:0000029, GO:0005525=GO_REF:0000037, GO:0006184=PMID:9030196, GO:0045335=PMID:21255211, GO:0005739=GO_REF:0000019, GO:0051286=GO_REF:0000019, GO:0031346=GO_REF:0000019, GO:0030670=GO_REF:0000039, GO:0051461=GO_REF:0000019, GO:0019003=PMID:20937701, GO:0005778=PMID:18346465, GO:0034332=GO_REF:0000024} Q92930 Ras-related protein Rab-8B protein 20130413 {GO:0030911=IEA, GO:0048471=IEA, GO:0005886=IEA, GO:0007264=IEA, GO:0005102=IPI, GO:0003924=NAS, GO:0005575=ND, GO:0015031=NAS, GO:0005525=IEA, GO:0006184=NAS, GO:0045335=IDA, GO:0005739=IEA, GO:0051286=IEA, GO:0031346=IEA, GO:0030670=IEA, GO:0051461=IEA, GO:0019003=IDA, GO:0005778=IDA, GO:0034332=ISS} GTP catabolic process, adherens junction organization, positive regulation of cell projection organization, positive regulation of corticotropin secretion, protein transport, small GTPase mediated signal transduction cell tip, cellular_component, mitochondrion, perinuclear region of cytoplasm, peroxisomal membrane, phagocytic vesicle, phagocytic vesicle membrane, plasma membrane GDP binding, GTP binding, GTPase activity, TPR domain binding, receptor binding Human RAB9A GOC UniProtKB {GO:0005515=PMID:18243103, GO:0005886=GO_REF:0000039, GO:0005770=PMID:15078902, GO:0007264=GO_REF:0000002, GO:0003924=PMID:15263003, GO:0015031=GO_REF:0000037, GO:0005525=PMID:15263003, GO:0005764=PMID:15078902, GO:0006184=PMID:9126495, GO:0045335=PMID:21255211, GO:0045921=PMID:19966785, GO:0000139=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0030670=GO_REF:0000039, GO:0019003=PMID:20937701} P51151 Ras-related protein Rab-9A protein 20130413 {GO:0005515=IPI, GO:0005886=IEA, GO:0005770=IDA, GO:0007264=IEA, GO:0003924=IDA, GO:0015031=IEA, GO:0005525=IDA, GO:0005764=IDA, GO:0006184=TAS, GO:0045335=IDA, GO:0045921=IMP, GO:0000139=IEA, GO:0005789=IEA, GO:0030670=IEA, GO:0019003=IDA} GTP catabolic process, positive regulation of exocytosis, protein transport, small GTPase mediated signal transduction Golgi membrane, endoplasmic reticulum membrane, late endosome, lysosome, phagocytic vesicle, phagocytic vesicle membrane, plasma membrane GDP binding, GTP binding, GTPase activity, protein binding Human RAB9B UniProtKB UniProtKB {GO:0045335=PMID:21255211, GO:0005515=PMID:19490898, GO:0005886=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0030670=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0019003=PMID:20937701, GO:0005525=GO_REF:0000029, GO:0015031=GO_REF:0000037, GO:0006895=GO_REF:0000029} Q9NP90 Ras-related protein Rab-9B protein 20130108 {GO:0045335=IDA, GO:0005515=IPI, GO:0005886=IEA, GO:0007264=IEA, GO:0030670=IEA, GO:0005575=ND, GO:0019003=IDA, GO:0005525=NAS, GO:0015031=IEA, GO:0006895=NAS} Golgi to endosome transport, protein transport, small GTPase mediated signal transduction cellular_component, phagocytic vesicle, phagocytic vesicle membrane, plasma membrane GDP binding, GTP binding, protein binding Human RABAC1 IntAct UniProtKB {GO:0005515=PMID:21798244, GO:0005794=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000019, GO:0008022=GO_REF:0000019, GO:0070064=GO_REF:0000019, GO:0042802=PMID:19060904, GO:0008021=GO_REF:0000039} Q9UI14 Prenylated Rab acceptor protein 1 protein 20130415 {GO:0005515=IPI, GO:0005794=IEA, GO:0030054=IEA, GO:0005886=IEA, GO:0016021=IEA, GO:0008022=IEA, GO:0070064=IEA, GO:0042802=IPI, GO:0008021=IEA} Golgi apparatus, cell junction, integral to membrane, plasma membrane, synaptic vesicle identical protein binding, proline-rich region binding, protein C-terminus binding, protein binding Human UniProtKB:Q9UI14 RABEP1 IntAct UniProtKB {GO:0005515=PMID:15457209, GO:0006944=PMID:8521472, GO:0006915=GO_REF:0000037, GO:0030139=PMID:20682791, GO:0055037=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0008083=GO_REF:0000002, GO:0042803=PMID:15378032, GO:0005769=GO_REF:0000039, GO:0005768=PMID:20682791, GO:0006897=GO_REF:0000037, GO:0005096=GO_REF:0000002} Q15276 Rab GTPase-binding effector protein 1 protein 20130415 {GO:0005515=IPI, GO:0006944=TAS, GO:0006915=IEA, GO:0030139=IDA, GO:0055037=IEA, GO:0015031=IEA, GO:0008083=IEA, GO:0042803=IPI, GO:0005769=IEA, GO:0005768=IDA, GO:0006897=IEA, GO:0005096=IEA} apoptotic process, cellular membrane fusion, endocytosis, protein transport early endosome, endocytic vesicle, endosome, recycling endosome GTPase activator activity, growth factor activity, protein binding, protein homodimerization activity Human UniProtKB:Q9UJY5 RABEP2 UniProtKB UniProtKB {GO:0015031=GO_REF:0000037, GO:0008083=GO_REF:0000002, GO:0005769=GO_REF:0000039, GO:0006897=GO_REF:0000037, GO:0005096=GO_REF:0000002} Q9H5N1 Rab GTPase-binding effector protein 2 protein 20130413 {GO:0015031=IEA, GO:0008083=IEA, GO:0005769=IEA, GO:0006897=IEA, GO:0005096=IEA} endocytosis, protein transport early endosome GTPase activator activity, growth factor activity Human UniProtKB-SubCell:SL-0094 RABEPK HPA UniProtKB {GO:0005886=GO_REF:0000052, GO:0006898=PMID:9230071, GO:0010008=GO_REF:0000039, GO:0043231=GO_REF:0000052, GO:0005768=PMID:9230071, GO:0006904=PMID:9230071} Q7Z6M1 Rab9 effector protein with kelch motifs protein 20100326 {GO:0005886=IDA, GO:0006898=TAS, GO:0010008=IEA, GO:0043231=IDA, GO:0005768=TAS, GO:0006904=TAS} receptor-mediated endocytosis, vesicle docking involved in exocytosis endosome, endosome membrane, intracellular membrane-bounded organelle, plasma membrane Human RABGAP1 GOC UniProtKB {GO:0043547=PMID:10202141, GO:0005515=PMID:20562859, GO:0005622=GO_REF:0000002, GO:0005813=PMID:10202141, GO:0007049=GO_REF:0000037, GO:0015631=PMID:10202141, GO:0005875=PMID:10202141, GO:0003677=GO_REF:0000002, GO:0005097=GO_REF:0000002, GO:0005096=PMID:10202141, GO:0005829=GO_REF:0000039} Q9Y3P9 Rab GTPase-activating protein 1 protein 20130413 {GO:0043547=TAS, GO:0005515=IPI, GO:0005622=IEA, GO:0005813=TAS, GO:0007049=IEA, GO:0015631=TAS, GO:0005875=TAS, GO:0003677=IEA, GO:0005097=IEA, GO:0005096=TAS, GO:0005829=IEA} cell cycle, positive regulation of GTPase activity centrosome, cytosol, intracellular, microtubule associated complex DNA binding, GTPase activator activity, Rab GTPase activator activity, protein binding, tubulin binding Human RABGAP1L GOC UniProtKB {GO:0032880=PMID:16923123, GO:0005622=GO_REF:0000002, GO:0017137=PMID:16923123, GO:0005794=PMID:16923123, GO:0032851=PMID:16923123, GO:0005634=PMID:16923123, GO:0005769=PMID:16923123, GO:0005097=PMID:16923123} Q5R372 Rab GTPase-activating protein 1-like protein 20130413 {GO:0032880=IDA, GO:0005622=IEA, GO:0017137=IDA, GO:0005794=IDA, GO:0032851=IDA, GO:0005634=IDA, GO:0005769=IDA, GO:0005097=IDA} positive regulation of Rab GTPase activity, regulation of protein localization Golgi apparatus, early endosome, intracellular, nucleus Rab GTPase activator activity, Rab GTPase binding Human RABGEF1 IntAct UniProtKB {GO:0005515=PMID:16499958, GO:0017112=PMID:20937701, GO:0008270=GO_REF:0000002, GO:0055037=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0003677=GO_REF:0000002, GO:0005769=GO_REF:0000039, GO:0006897=GO_REF:0000037} Q9UJ41 Rab5 GDP/GTP exchange factor protein 20130415 {GO:0005515=IPI, GO:0017112=IDA, GO:0008270=IEA, GO:0055037=IEA, GO:0015031=IEA, GO:0003677=IEA, GO:0005769=IEA, GO:0006897=IEA} endocytosis, protein transport early endosome, recycling endosome DNA binding, Rab guanyl-nucleotide exchange factor activity, protein binding, zinc ion binding Human UniProtKB:P0CG47 RABGGTA PINC UniProtKB {GO:0018342=GO_REF:0000002, GO:0018344=GO_REF:0000019, GO:0004663=GO_REF:0000003, GO:0008270=GO_REF:0000002, GO:0007601=PMID:8380507, GO:0008318=GO_REF:0000002, GO:0006464=PMID:8380507} Q92696 Geranylgeranyl transferase type-2 subunit alpha protein 20030904 {GO:0018342=IEA, GO:0018344=IEA, GO:0004663=IEA, GO:0008270=IEA, GO:0007601=TAS, GO:0008318=IEA, GO:0006464=TAS} cellular protein modification process, protein geranylgeranylation, protein prenylation, visual perception Rab geranylgeranyltransferase activity, protein prenyltransferase activity, zinc ion binding Human RABGGTB InterPro UniProtKB {GO:0005515=PMID:12620389, GO:0018344=GO_REF:0000002, GO:0004663=GO_REF:0000003, GO:0003824=GO_REF:0000002, GO:0007601=PMID:8380507, GO:0006464=PMID:8380507, GO:0046872=GO_REF:0000037} Q5T4U8 Geranylgeranyl transferase type-2 subunit beta protein 20130413 {GO:0005515=IPI, GO:0018344=IEA, GO:0004663=IEA, GO:0003824=IEA, GO:0007601=TAS, GO:0006464=NAS, GO:0046872=IEA} cellular protein modification process, protein geranylgeranylation, visual perception Rab geranylgeranyltransferase activity, catalytic activity, metal ion binding, protein binding Human InterPro:IPR001330 RABIF PINC UniProtKB {GO:0005085=PMID:7619808, GO:0006944=PMID:9441742, GO:0007264=GO_REF:0000002, GO:0008270=PMID:7619808, GO:0015031=GO_REF:0000037} P47224 Guanine nucleotide exchange factor MSS4 protein 20030904 {GO:0005085=NAS, GO:0006944=TAS, GO:0007264=IEA, GO:0008270=IDA, GO:0015031=IEA} cellular membrane fusion, protein transport, small GTPase mediated signal transduction guanyl-nucleotide exchange factor activity, zinc ion binding Human RABL2A GOC UniProtKB {GO:0006184=PMID:10444334, GO:0007264=GO_REF:0000002, GO:0003924=PMID:10444334, GO:0005525=GO_REF:0000037} Q9UBK7 Rab-like protein 2A protein 20130413 {GO:0006184=TAS, GO:0007264=IEA, GO:0003924=TAS, GO:0005525=IEA} GTP catabolic process, small GTPase mediated signal transduction GTP binding, GTPase activity Human RABL2B GOC UniProtKB {GO:0006184=PMID:10444334, GO:0007264=GO_REF:0000002, GO:0003924=PMID:10444334, GO:0005525=GO_REF:0000037} Q9UNT1 Rab-like protein 2B protein 20130413 {GO:0006184=TAS, GO:0007264=IEA, GO:0003924=TAS, GO:0005525=IEA} GTP catabolic process, small GTPase mediated signal transduction GTP binding, GTPase activity Human RABL3 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q5HYI8 Rab-like protein 3 protein 20130413 {GO:0005622=IEA, GO:0007264=IEA, GO:0005525=IEA} small GTPase mediated signal transduction intracellular GTP binding Human UniProtKB-KW:KW-0342 RABL5 UniProtKB UniProtKB {GO:0007264=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q9H7X7 Rab-like protein 5 protein 20130413 {GO:0007264=IEA, GO:0005525=IEA} small GTPase mediated signal transduction GTP binding Human UniProtKB-KW:KW-0342 RAC1 BHF-UCL UniProtKB {GO:0005515=PMID:16636067, GO:0005802=PMID:12915445, GO:0045453=GO_REF:0000019, GO:0009653=PMID:9572733, GO:0031529=PMID:15467718, GO:0030838=GO_REF:0000019, GO:0043552=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0021799=GO_REF:0000019, GO:0034446=GO_REF:0000019, GO:0097178=GO_REF:0000019, GO:0030334=PMID:22036506, GO:0042470=GO_REF:0000039, GO:0017137=GO_REF:0000019, GO:0021831=GO_REF:0000019, GO:0019901=GO_REF:0000019, GO:0045740=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0001891=GO_REF:0000019, GO:0045216=GO_REF:0000019, GO:0030027=GO_REF:0000019, GO:0030742=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0019899=PMID:16636067, GO:0038096=Reactome:REACT_160123, GO:0019897=GO_REF:0000019, GO:0030036=PMID:19890013, GO:0005886=Reactome:REACT_13694, GO:0007264=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:0031295=Reactome:REACT_19344, GO:0035025=PMID:9312003, GO:0030032=PMID:9312003, GO:0003924=PMID:9312003, GO:0060263=PMID:16636067, GO:0006928=PMID:9572733, GO:0031996=PMID:12612085, GO:0005829=Reactome:REACT_160291, GO:0035556=PMID:9572733, GO:0010592=PMID:15467718, GO:0006954=PMID:9572733, GO:0048870=PMID:19403692, GO:0030041=PMID:9312003, GO:0010310=PMID:16636067, GO:0016032=Reactome:REACT_6185, GO:0090103=GO_REF:0000019, GO:0051668=PMID:16636067, GO:0007155=PMID:9572733, GO:0060071=GO_REF:0000019, GO:0003382=GO_REF:0000019, GO:0048011=Reactome:REACT_13776, GO:0032707=PMID:16982892, GO:0009611=PMID:9572733, GO:0006915=Reactome:REACT_13638, GO:0032587=GO_REF:0000019, GO:0005525=PMID:15467718, GO:0043652=GO_REF:0000019, GO:0006972=GO_REF:0000019, GO:0097190=Reactome:REACT_13720, GO:0050690=Reactome:REACT_11068, GO:0048813=GO_REF:0000019, GO:0007160=PMID:18156211, GO:0000139=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0071542=GO_REF:0000019, GO:0048261=PMID:9312003, GO:0002551=GO_REF:0000019, GO:0048532=GO_REF:0000019, GO:0002093=GO_REF:0000019} P63000 Ras-related C3 botulinum toxin substrate 1 protein 20110113 {GO:0005515=IPI, GO:0005802=IDA, GO:0045453=IEA, GO:0009653=TAS, GO:0031529=IDA, GO:0030838=IEA, GO:0043552=IEA, GO:0007411=TAS, GO:0021799=IEA, GO:0034446=IEA, GO:0097178=IEA, GO:0030334=IMP, GO:0042470=IEA, GO:0017137=IEA, GO:0021831=IEA, GO:0019901=IEA, GO:0045740=IEA, GO:0030168=TAS, GO:0001891=IEA, GO:0045216=IEA, GO:0030027=IEA, GO:0030742=IEA, GO:0045087=TAS, GO:0019899=IPI, GO:0038096=TAS, GO:0019897=IEA, GO:0030036=IGI, GO:0005886=TAS, GO:0007264=IEA, GO:0008283=IEA, GO:0031295=TAS, GO:0035025=TAS, GO:0030032=IMP, GO:0003924=TAS, GO:0060263=IDA, GO:0006928=TAS, GO:0031996=IPI, GO:0005829=TAS, GO:0035556=TAS, GO:0010592=IDA, GO:0006954=TAS, GO:0048870=IDA, GO:0030041=TAS, GO:0010310=TAS, GO:0016032=TAS, GO:0090103=IEA, GO:0051668=IMP, GO:0007155=TAS, GO:0060071=IEA, GO:0003382=IEA, GO:0048011=TAS, GO:0032707=IDA, GO:0009611=TAS, GO:0006915=TAS, GO:0032587=IEA, GO:0005525=IDA, GO:0043652=IEA, GO:0006972=IEA, GO:0097190=TAS, GO:0050690=TAS, GO:0048813=IEA, GO:0007160=NAS, GO:0000139=IEA, GO:0007596=TAS, GO:0071542=IEA, GO:0048261=TAS, GO:0002551=IEA, GO:0048532=IEA, GO:0002093=IEA} Fc-gamma receptor signaling pathway involved in phagocytosis, T cell costimulation, Wnt receptor signaling pathway, planar cell polarity pathway, actin cytoskeleton organization, actin filament polymerization, anatomical structure arrangement, anatomical structure morphogenesis, apoptotic process, apoptotic signaling pathway, auditory receptor cell morphogenesis, axon guidance, blood coagulation, bone resorption, cell adhesion, cell motility, cell proliferation, cell-cell junction organization, cell-matrix adhesion, cellular component movement, cerebral cortex radially oriented cell migration, cochlea morphogenesis, dendrite morphogenesis, dopaminergic neuron differentiation, embryonic olfactory bulb interneuron precursor migration, engulfment of apoptotic cell, epithelial cell morphogenesis, hyperosmotic response, inflammatory response, innate immune response, intracellular signal transduction, lamellipodium assembly, localization within membrane, mast cell chemotaxis, negative regulation of interleukin-23 production, negative regulation of receptor-mediated endocytosis, neurotrophin TRK receptor signaling pathway, platelet activation, positive regulation of DNA replication, positive regulation of Rho protein signal transduction, positive regulation of actin filament polymerization, positive regulation of lamellipodium assembly, positive regulation of phosphatidylinositol 3-kinase activity, regulation of cell migration, regulation of defense response to virus by virus, regulation of hydrogen peroxide metabolic process, regulation of respiratory burst, response to wounding, ruffle assembly, ruffle organization, small GTPase mediated signal transduction, substrate adhesion-dependent cell spreading, viral reproduction Golgi membrane, cytosol, extrinsic to plasma membrane, lamellipodium, melanosome, phagocytic cup, plasma membrane, ruffle membrane, trans-Golgi network GTP binding, GTP-dependent protein binding, GTPase activity, Rab GTPase binding, enzyme binding, protein binding, protein kinase binding, thioesterase binding Human RAC2 BHF-UCL UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0008284=GO_REF:0000019, GO:0030036=GO_REF:0000019, GO:0005886=Reactome:REACT_10126, GO:0007264=Reactome:REACT_11044, GO:0045453=GO_REF:0000019, GO:0003924=GO_REF:0000019, GO:0060263=PMID:16636067, GO:0030168=Reactome:REACT_798, GO:0005635=GO_REF:0000019, GO:0005525=GO_REF:0000037, GO:0005829=Reactome:REACT_24016, GO:0005622=GO_REF:0000002, GO:0007165=PMID:2674130, GO:0005737=GO_REF:0000019, GO:0006935=GO_REF:0000019, GO:0016020=GO_REF:0000038, GO:0007596=Reactome:REACT_604, GO:0007411=Reactome:REACT_18266, GO:0030031=GO_REF:0000019, GO:0010310=PMID:16636067} P15153 Ras-related C3 botulinum toxin substrate 2 protein 20080620 {GO:0051056=TAS, GO:0008284=IEA, GO:0030036=IEA, GO:0005886=TAS, GO:0007264=TAS, GO:0045453=IEA, GO:0003924=IEA, GO:0060263=IDA, GO:0030168=TAS, GO:0005635=IEA, GO:0005525=IEA, GO:0005829=TAS, GO:0005622=IEA, GO:0007165=TAS, GO:0005737=IEA, GO:0006935=IEA, GO:0016020=IEA, GO:0007596=TAS, GO:0007411=TAS, GO:0030031=IEA, GO:0010310=TAS} actin cytoskeleton organization, axon guidance, blood coagulation, bone resorption, cell projection assembly, chemotaxis, platelet activation, positive regulation of cell proliferation, regulation of hydrogen peroxide metabolic process, regulation of respiratory burst, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytoplasm, cytosol, intracellular, membrane, nuclear envelope, plasma membrane GTP binding, GTPase activity Human RAC3 GOC UniProtKB {GO:0005515=PMID:21217774, GO:0051056=Reactome:REACT_11051, GO:0043005=PMID:16525025, GO:0030036=PMID:11956649, GO:0005886=Reactome:REACT_10126, GO:0007264=Reactome:REACT_11044, GO:0003924=PMID:11956649, GO:0005525=GO_REF:0000037, GO:0031175=GO_REF:0000019, GO:0030027=GO_REF:0000039, GO:0005829=Reactome:REACT_10055, GO:0012505=PMID:11956649, GO:0030426=PMID:16525025, GO:0006184=PMID:11956649, GO:0005622=GO_REF:0000002, GO:0035556=PMID:9252344, GO:0031941=PMID:16525025, GO:0016020=GO_REF:0000038, GO:0030031=PMID:11956649, GO:0043025=PMID:16525025, GO:0050885=GO_REF:0000019} P60763 Ras-related C3 botulinum toxin substrate 3 protein 20130413 {GO:0005515=IPI, GO:0051056=TAS, GO:0043005=IDA, GO:0030036=IDA, GO:0005886=TAS, GO:0007264=TAS, GO:0003924=IDA, GO:0005525=IEA, GO:0031175=IEA, GO:0030027=IEA, GO:0005829=TAS, GO:0012505=IDA, GO:0030426=IDA, GO:0006184=IDA, GO:0005622=IEA, GO:0035556=TAS, GO:0031941=IDA, GO:0016020=IEA, GO:0030031=IDA, GO:0043025=IDA, GO:0050885=IEA} GTP catabolic process, actin cytoskeleton organization, cell projection assembly, intracellular signal transduction, neuromuscular process controlling balance, neuron projection development, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol, endomembrane system, filamentous actin, growth cone, intracellular, lamellipodium, membrane, neuron projection, neuronal cell body, plasma membrane GTP binding, GTPase activity, protein binding Human RACGAP1 GOC UniProtKB {GO:0051256=PMID:16103226, GO:0005515=PMID:11278976, GO:0008017=PMID:11782313, GO:0072686=PMID:16103226, GO:0007264=Reactome:REACT_11044, GO:0005634=GO_REF:0000054, GO:0009790=GO_REF:0000024, GO:0007283=PMID:12590651, GO:0007108=PMID:16129829, GO:0051233=PMID:19468302, GO:0032154=PMID:16103226, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_120995, GO:0007405=GO_REF:0000024, GO:0005622=GO_REF:0000002, GO:0019886=Reactome:REACT_121399, GO:0000910=PMID:19468302, GO:0000915=PMID:16129829, GO:0007018=Reactome:REACT_25201, GO:0051056=Reactome:REACT_11051, GO:0043015=PMID:11085985, GO:0001669=GO_REF:0000039, GO:0019901=PMID:19468302, GO:0043014=PMID:11085985, GO:0051988=PMID:15642749, GO:0005874=GO_REF:0000037, GO:0048487=PMID:11085985, GO:0030496=PMID:16103226, GO:0043547=PMID:15642749, GO:0007165=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0008272=PMID:11278976, GO:0097149=PMID:16236794, GO:0005096=PMID:15642749} Q9H0H5 Rac GTPase-activating protein 1 protein 20130413 {GO:0051256=IDA, GO:0005515=IPI, GO:0008017=IDA, GO:0072686=IDA, GO:0007264=TAS, GO:0005634=IDA, GO:0009790=ISS, GO:0007283=IEP, GO:0007108=IMP, GO:0051233=IDA, GO:0032154=IDA, GO:0046872=IEA, GO:0005829=TAS, GO:0007405=ISS, GO:0005622=IEA, GO:0019886=TAS, GO:0000910=IDA, GO:0000915=IMP, GO:0007018=TAS, GO:0051056=TAS, GO:0043015=IDA, GO:0001669=IEA, GO:0019901=IPI, GO:0043014=IDA, GO:0051988=IMP, GO:0005874=IEA, GO:0048487=IDA, GO:0030496=IDA, GO:0043547=IMP, GO:0007165=IEA, GO:0007596=TAS, GO:0008272=IDA, GO:0097149=IDA, GO:0005096=IMP} antigen processing and presentation of exogenous peptide antigen via MHC class II, blood coagulation, cytokinesis, cytokinesis, actomyosin contractile ring assembly, cytokinesis, initiation of separation, embryo development, microtubule-based movement, neuroblast proliferation, positive regulation of GTPase activity, regulation of attachment of spindle microtubules to kinetochore, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction, spermatogenesis, spindle midzone assembly involved in mitosis, sulfate transport acrosomal vesicle, centralspindlin complex, cleavage furrow, cytosol, intracellular, microtubule, midbody, mitotic spindle, nucleus, spindle midzone GTPase activator activity, alpha-tubulin binding, beta-tubulin binding, gamma-tubulin binding, metal ion binding, microtubule binding, protein binding, protein kinase binding Human RAD1 HPA UniProtKB {GO:0005515=PMID:19464297, GO:0008408=PMID:9660799, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0071479=PMID:21659603, GO:0006974=PMID:9872989, GO:0043231=GO_REF:0000052, GO:0003684=PMID:9660799, GO:0006260=Reactome:REACT_6769, GO:0007128=PMID:9716408, GO:0006281=GO_REF:0000037, GO:0008853=GO_REF:0000003, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_6729, GO:0000077=PMID:21659603} O60671 Cell cycle checkpoint protein RAD1 protein 20090616 {GO:0005515=IPI, GO:0008408=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0071479=IDA, GO:0006974=TAS, GO:0043231=IDA, GO:0003684=NAS, GO:0006260=TAS, GO:0007128=TAS, GO:0006281=IEA, GO:0008853=IEA, GO:0000075=TAS, GO:0005654=TAS, GO:0000077=IMP} DNA damage checkpoint, DNA repair, DNA replication, cell cycle checkpoint, cellular response to ionizing radiation, meiotic prophase I, response to DNA damage stimulus intracellular membrane-bounded organelle, nucleolus, nucleoplasm, nucleus 3'-5' exonuclease activity, damaged DNA binding, exodeoxyribonuclease III activity, protein binding Human RAD17 HPA UniProtKB {GO:0005515=PMID:15538388, GO:0000781=PMID:15149599, GO:0017111=GO_REF:0000002, GO:0007093=PMID:15538388, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037, GO:0006974=PMID:15538388, GO:0006260=Reactome:REACT_6769, GO:0042325=PMID:14657349, GO:0007049=GO_REF:0000002, GO:0006281=GO_REF:0000002, GO:0000076=PMID:9660800, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_6798, GO:0000077=PMID:15538388, GO:0008156=PMID:14657349} O75943 Cell cycle checkpoint protein RAD17 protein 20101115 {GO:0005515=IPI, GO:0000781=IDA, GO:0017111=IEA, GO:0007093=IMP, GO:0005730=IDA, GO:0005634=IDA, GO:0005524=IEA, GO:0006974=IMP, GO:0006260=TAS, GO:0042325=IMP, GO:0007049=IEA, GO:0006281=IEA, GO:0000076=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0000077=IMP, GO:0008156=IMP} DNA damage checkpoint, DNA repair, DNA replication, DNA replication checkpoint, cell cycle, cell cycle checkpoint, mitotic cell cycle checkpoint, negative regulation of DNA replication, regulation of phosphorylation, response to DNA damage stimulus chromosome, telomeric region, nucleolus, nucleoplasm, nucleus ATP binding, nucleoside-triphosphatase activity, protein binding NOT Human RAD18 UniProtKB UniProtKB {GO:0005515=PMID:22681887, GO:0001741=GO_REF:0000019, GO:0016567=GO_REF:0000041, GO:0005657=PMID:18363965, GO:0016874=GO_REF:0000037, GO:0000403=PMID:18363965, GO:0005634=PMID:10884424, GO:0007283=GO_REF:0000019, GO:0003677=GO_REF:0000002, GO:0006974=GO_REF:0000019, GO:0003684=PMID:10884424, GO:0006281=PMID:10884424, GO:0008270=GO_REF:0000002, GO:0000785=GO_REF:0000019, GO:0009411=GO_REF:0000019, GO:0031625=PMID:10908344, GO:0045910=GO_REF:0000019, GO:0031593=PMID:22742833} Q9NS91 E3 ubiquitin-protein ligase RAD18 protein 20120726 {GO:0005515=IPI, GO:0001741=IEA, GO:0016567=IEA, GO:0005657=IDA, GO:0016874=IEA, GO:0000403=IDA, GO:0005634=NAS, GO:0007283=IEA, GO:0003677=IEA, GO:0006974=IEA, GO:0003684=NAS, GO:0006281=NAS, GO:0008270=IEA, GO:0000785=IEA, GO:0009411=IEA, GO:0031625=IPI, GO:0045910=IEA, GO:0031593=IDA} DNA repair, negative regulation of DNA recombination, protein ubiquitination, response to DNA damage stimulus, response to UV, spermatogenesis XY body, chromatin, nucleus, replication fork DNA binding, Y-form DNA binding, damaged DNA binding, ligase activity, polyubiquitin binding, protein binding, ubiquitin protein ligase binding, zinc ion binding Human UniProtKB:Q9H040 RAD21 BHF-UCL UniProtKB {GO:0005515=PMID:15837422, GO:0000236=Reactome:REACT_682, GO:0006357=PMID:19468298, GO:0005694=Reactome:REACT_150454, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0006310=PMID:8812457, GO:0005829=Reactome:REACT_150294, GO:0006302=PMID:8812457, GO:0000084=Reactome:REACT_899, GO:0000910=Reactome:REACT_1932, GO:0008278=PMID:19468298, GO:0007059=GO_REF:0000037, GO:0000087=Reactome:REACT_910, GO:0005654=Reactome:REACT_150456, GO:0034991=GO_REF:0000019, GO:0071168=PMID:21111234, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0000775=Reactome:REACT_150445, GO:0007131=PMID:8812457} O60216 Double-strand-break repair protein rad21 homolog protein 20100120 {GO:0005515=IPI, GO:0000236=TAS, GO:0006357=IDA, GO:0005694=TAS, GO:0005730=IDA, GO:0006915=IEA, GO:0005634=IDA, GO:0006310=TAS, GO:0005829=TAS, GO:0006302=TAS, GO:0000084=TAS, GO:0000910=TAS, GO:0008278=TAS, GO:0007059=IEA, GO:0000087=TAS, GO:0005654=TAS, GO:0034991=IEA, GO:0071168=IMP, GO:0000278=TAS, GO:0000090=TAS, GO:0000775=TAS, GO:0007131=TAS} DNA recombination, M phase of mitotic cell cycle, S phase of mitotic cell cycle, apoptotic process, chromosome segregation, cytokinesis, double-strand break repair, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, protein localization to chromatin, reciprocal meiotic recombination, regulation of transcription from RNA polymerase II promoter chromosome, chromosome, centromeric region, cohesin complex, cytosol, nuclear meiotic cohesin complex, nucleolus, nucleoplasm, nucleus protein binding Human RAD21L1 UniProtKB UniProtKB {GO:0007129=GO_REF:0000019, GO:0007128=GO_REF:0000024, GO:0007059=GO_REF:0000037, GO:0005694=GO_REF:0000024, GO:0030893=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0007283=GO_REF:0000019, GO:0000800=GO_REF:0000019, GO:0070197=GO_REF:0000019, GO:0006302=GO_REF:0000019} Q9H4I0 Double-strand-break repair protein rad21-like protein 1 protein 20110222 {GO:0007129=IEA, GO:0007128=ISS, GO:0007059=IEA, GO:0005694=ISS, GO:0030893=ISS, GO:0005634=ISS, GO:0007283=IEA, GO:0000800=IEA, GO:0070197=IEA, GO:0006302=IEA} attachment of telomeric heterochromatin to nuclear envelope, chromosome segregation, double-strand break repair, meiotic prophase I, spermatogenesis, synapsis chromosome, lateral element, meiotic cohesin complex, nucleus Human UniProtKB:A2AU37 RAD23A IntAct UniProtKB {GO:0005515=PMID:17098253, GO:0003684=GO_REF:0000002, GO:0000502=GO_REF:0000037, GO:0003697=PMID:8168482, GO:0019048=GO_REF:0000037, GO:0032434=PMID:12643283, GO:0043161=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0006289=PMID:9372924, GO:0045070=PMID:20614012, GO:0031593=PMID:12643283} P54725 UV excision repair protein RAD23 homolog A protein 20130415 {GO:0005515=IPI, GO:0003684=IEA, GO:0000502=IEA, GO:0003697=TAS, GO:0019048=IEA, GO:0032434=IDA, GO:0043161=IEA, GO:0005634=IEA, GO:0006289=IDA, GO:0045070=IMP, GO:0031593=IDA} nucleotide-excision repair, positive regulation of viral genome replication, proteasomal ubiquitin-dependent protein catabolic process, regulation of proteasomal ubiquitin-dependent protein catabolic process, virus-host interaction nucleus, proteasome complex damaged DNA binding, polyubiquitin binding, protein binding, single-stranded DNA binding Human UniProtKB:Q9UHD9 RAD23B ENSEMBL UniProtKB {GO:0005515=PMID:21962512, GO:0000502=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0071942=PMID:11279143, GO:0005634=GO_REF:0000052, GO:0032434=PMID:19435460, GO:0007283=GO_REF:0000019, GO:0006974=GO_REF:0000019, GO:0003684=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0006281=Reactome:REACT_216, GO:0003697=PMID:8168482, GO:0000715=Reactome:REACT_476, GO:0043161=GO_REF:0000002, GO:0005654=Reactome:REACT_2163, GO:0006289=Reactome:REACT_1826, GO:0000718=Reactome:REACT_311, GO:0031593=PMID:19435460} Q5W0S5 UV excision repair protein RAD23 homolog B protein 20130413 {GO:0005515=IPI, GO:0000502=IEA, GO:0005730=IDA, GO:0071942=IDA, GO:0005634=IDA, GO:0032434=IDA, GO:0007283=IEA, GO:0006974=IEA, GO:0003684=IEA, GO:0005737=IDA, GO:0006281=TAS, GO:0003697=TAS, GO:0000715=TAS, GO:0043161=IEA, GO:0005654=TAS, GO:0006289=TAS, GO:0000718=TAS, GO:0031593=IDA} DNA repair, nucleotide-excision repair, nucleotide-excision repair, DNA damage recognition, nucleotide-excision repair, DNA damage removal, proteasomal ubiquitin-dependent protein catabolic process, regulation of proteasomal ubiquitin-dependent protein catabolic process, response to DNA damage stimulus, spermatogenesis XPC complex, cytoplasm, nucleolus, nucleoplasm, nucleus, proteasome complex damaged DNA binding, polyubiquitin binding, protein binding, single-stranded DNA binding Human Ensembl:ENSMUSP00000030134 RAD50 BHF-UCL UniProtKB {GO:0005515=PMID:11096100, GO:0008408=PMID:9705271, GO:0030870=PMID:19151086, GO:0006302=Reactome:REACT_2054, GO:0004003=PMID:15790808, GO:0000723=PMID:10888888, GO:0000724=Reactome:REACT_1874, GO:0032508=PMID:15790808, GO:0030674=PMID:12152085, GO:0000784=PMID:10888888, GO:0007131=PMID:8756642, GO:0031954=PMID:15790808, GO:0033674=PMID:15790808, GO:0006310=PMID:9705271, GO:0005524=GO_REF:0000037, GO:0003677=PMID:15790808, GO:0006974=PMID:17500065, GO:0004518=GO_REF:0000002, GO:0006281=Reactome:REACT_216, GO:0000014=PMID:9705271, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_1232, GO:0045120=GO_REF:0000019, GO:0007004=PMID:9705271, GO:0000019=PMID:8756642} Q92878 DNA repair protein RAD50 protein 20081217 {GO:0005515=IPI, GO:0008408=IDA, GO:0030870=IDA, GO:0006302=TAS, GO:0004003=IMP, GO:0000723=TAS, GO:0000724=TAS, GO:0032508=IMP, GO:0030674=IDA, GO:0000784=IDA, GO:0007131=TAS, GO:0031954=IDA, GO:0033674=IDA, GO:0006310=IDA, GO:0005524=IEA, GO:0003677=IDA, GO:0006974=IDA, GO:0004518=IEA, GO:0006281=TAS, GO:0000014=IDA, GO:0008270=IEA, GO:0005654=TAS, GO:0045120=IEA, GO:0007004=IDA, GO:0000019=IDA} DNA duplex unwinding, DNA recombination, DNA repair, double-strand break repair, double-strand break repair via homologous recombination, positive regulation of kinase activity, positive regulation of protein autophosphorylation, reciprocal meiotic recombination, regulation of mitotic recombination, response to DNA damage stimulus, telomere maintenance, telomere maintenance via telomerase Mre11 complex, nuclear chromosome, telomeric region, nucleoplasm, pronucleus 3'-5' exonuclease activity, ATP binding, ATP-dependent DNA helicase activity, DNA binding, nuclease activity, protein binding, protein binding, bridging, single-stranded DNA specific endodeoxyribonuclease activity, zinc ion binding Human RAD51 ENSEMBL UniProtKB {GO:0005515=PMID:21965664, GO:0000793=GO_REF:0000024, GO:0048471=PMID:16215984, GO:0005634=PMID:18417535, GO:0042802=PMID:12442171, GO:0006302=Reactome:REACT_2054, GO:0005739=PMID:20413593, GO:0005737=PMID:16215984, GO:0003690=PMID:7988572, GO:0003697=PMID:7988572, GO:0000724=GO_REF:0000019, GO:0005759=GO_REF:0000039, GO:0051260=PMID:12442171, GO:0007131=PMID:8358431, GO:0008094=GO_REF:0000002, GO:0043142=PMID:8929543, GO:0000794=GO_REF:0000024, GO:0006310=PMID:7988572, GO:0000800=GO_REF:0000019, GO:0006312=PMID:8358431, GO:0008022=PMID:17515903, GO:0003677=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0003684=GO_REF:0000002, GO:0006281=Reactome:REACT_216, GO:0007126=GO_REF:0000019, GO:0000730=Reactome:REACT_2141, GO:0016605=PMID:11309417, GO:0006268=PMID:7988572, GO:0005654=Reactome:REACT_1612, GO:0051106=PMID:8929543} Q9NZG9 DNA repair protein RAD51 homolog 1 protein 20130413 {GO:0005515=IPI, GO:0000793=ISS, GO:0048471=IDA, GO:0005634=IDA, GO:0042802=IPI, GO:0006302=TAS, GO:0005739=IDA, GO:0005737=IDA, GO:0003690=IDA, GO:0003697=IDA, GO:0000724=IEA, GO:0005759=IEA, GO:0051260=IPI, GO:0007131=TAS, GO:0008094=IEA, GO:0043142=IDA, GO:0000794=ISS, GO:0006310=TAS, GO:0000800=IEA, GO:0006312=TAS, GO:0008022=IPI, GO:0003677=IEA, GO:0005524=IEA, GO:0003684=IEA, GO:0006281=TAS, GO:0007126=IEA, GO:0000730=TAS, GO:0016605=IDA, GO:0006268=IDA, GO:0005654=TAS, GO:0051106=IDA} DNA recombinase assembly, DNA recombination, DNA repair, DNA unwinding involved in replication, double-strand break repair, double-strand break repair via homologous recombination, meiosis, mitotic recombination, positive regulation of DNA ligation, protein homooligomerization, reciprocal meiotic recombination PML body, condensed chromosome, condensed nuclear chromosome, cytoplasm, lateral element, mitochondrial matrix, mitochondrion, nucleoplasm, nucleus, perinuclear region of cytoplasm ATP binding, DNA binding, DNA-dependent ATPase activity, damaged DNA binding, double-stranded DNA binding, identical protein binding, protein C-terminus binding, protein binding, single-stranded DNA binding, single-stranded DNA-dependent ATPase activity Human Ensembl:ENSMUSP00000028795 RAD51AP1 UniProtKB UniProtKB {GO:0005515=PMID:20871616, GO:0006281=PMID:9396801, GO:0003690=PMID:9396801, GO:0003697=PMID:9396801, GO:0000724=PMID:9396801, GO:0003723=PMID:9396801, GO:0006310=GO_REF:0000019, GO:0005634=PMID:9396801} Q96B01 RAD51-associated protein 1 protein 20101007 {GO:0005515=IPI, GO:0006281=NAS, GO:0003690=IDA, GO:0003697=IDA, GO:0000724=NAS, GO:0003723=IDA, GO:0006310=IEA, GO:0005634=IC} DNA recombination, DNA repair, double-strand break repair via homologous recombination nucleus RNA binding, double-stranded DNA binding, protein binding, single-stranded DNA binding Human UniProtKB:Q86YC2 RAD51AP2 null null {} null null null null {} null null null RAD51B IntAct UniProtKB {GO:0005515=PMID:21965664, GO:0006281=GO_REF:0000037, GO:0007596=Reactome:REACT_604, GO:0005654=Reactome:REACT_25328, GO:0006310=PMID:9512535, GO:0005634=PMID:9512535, GO:0006259=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0007131=PMID:9441753, GO:0008094=GO_REF:0000002} O15315 DNA repair protein RAD51 homolog 2 protein 20130415 {GO:0005515=IPI, GO:0006281=IEA, GO:0007596=TAS, GO:0005654=TAS, GO:0006310=TAS, GO:0005634=TAS, GO:0006259=IEA, GO:0005524=IEA, GO:0003677=IEA, GO:0007131=TAS, GO:0008094=IEA} DNA metabolic process, DNA recombination, DNA repair, blood coagulation, reciprocal meiotic recombination nucleoplasm, nucleus ATP binding, DNA binding, DNA-dependent ATPase activity, protein binding Human UniProtKB:Q6NVH7 RAD51C ENSEMBL UniProtKB {GO:0005515=PMID:21965664, GO:0048471=PMID:16215984, GO:0008821=GO_REF:0000019, GO:0005634=PMID:12966089, GO:0006310=PMID:19451272, GO:0006259=GO_REF:0000002, GO:0007283=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0005739=PMID:20413593, GO:0005737=PMID:16215984, GO:0006281=PMID:19451272, GO:0007596=Reactome:REACT_604, GO:0007062=GO_REF:0000024, GO:0005654=Reactome:REACT_25328, GO:0007066=GO_REF:0000019, GO:0007141=GO_REF:0000019, GO:0008094=GO_REF:0000002, GO:0007131=GO_REF:0000019} Q7KZJ0 DNA repair protein RAD51 homolog 3 protein 20130413 {GO:0005515=IPI, GO:0048471=IDA, GO:0008821=IEA, GO:0005634=IDA, GO:0006310=IDA, GO:0006259=IEA, GO:0007283=IEA, GO:0003677=IEA, GO:0005524=IEA, GO:0005739=IDA, GO:0005737=IDA, GO:0006281=IDA, GO:0007596=TAS, GO:0007062=ISS, GO:0005654=TAS, GO:0007066=IEA, GO:0007141=IEA, GO:0008094=IEA, GO:0007131=IEA} DNA metabolic process, DNA recombination, DNA repair, blood coagulation, female meiosis sister chromatid cohesion, male meiosis I, reciprocal meiotic recombination, sister chromatid cohesion, spermatogenesis cytoplasm, mitochondrion, nucleoplasm, nucleus, perinuclear region of cytoplasm ATP binding, DNA binding, DNA-dependent ATPase activity, crossover junction endodeoxyribonuclease activity, protein binding Human Ensembl:ENSMUSP00000064079 RAD51D IntAct UniProtKB {GO:0005515=PMID:21965664, GO:0006281=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006259=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0007131=PMID:9570954, GO:0008094=GO_REF:0000002} O75771 DNA repair protein RAD51 homolog 4 protein 20130415 {GO:0005515=IPI, GO:0006281=IEA, GO:0005634=IEA, GO:0006259=IEA, GO:0005524=IEA, GO:0003677=IEA, GO:0007131=TAS, GO:0008094=IEA} DNA metabolic process, DNA repair, reciprocal meiotic recombination nucleus ATP binding, DNA binding, DNA-dependent ATPase activity, protein binding Human UniProtKB:Q6NVH7 RAD52 InterPro UniProtKB {GO:0005515=PMID:19338310, GO:0006281=GO_REF:0000002, GO:0000724=Reactome:REACT_1874, GO:0000730=Reactome:REACT_2141, GO:0005654=Reactome:REACT_1465, GO:0005634=PMID:7774919, GO:0006310=GO_REF:0000002, GO:0006312=PMID:7774919, GO:0003677=PMID:7774919, GO:0006302=Reactome:REACT_2054, GO:0007131=PMID:7774919} Q9Y5T9 DNA repair protein RAD52 homolog protein 20130413 {GO:0005515=IPI, GO:0006281=IEA, GO:0000724=TAS, GO:0000730=TAS, GO:0005654=TAS, GO:0005634=TAS, GO:0006310=IEA, GO:0006312=TAS, GO:0003677=TAS, GO:0006302=TAS, GO:0007131=TAS} DNA recombinase assembly, DNA recombination, DNA repair, double-strand break repair, double-strand break repair via homologous recombination, mitotic recombination, reciprocal meiotic recombination nucleoplasm, nucleus DNA binding, protein binding Human InterPro:IPR007232 RAD54B GOC UniProtKB {GO:0003724=PMID:10362364, GO:0000724=PMID:16428451, GO:0015616=PMID:16428451, GO:0005634=GO_REF:0000039, GO:0032508=PMID:10362364, GO:0006312=PMID:10362364, GO:0005524=GO_REF:0000037, GO:0003678=PMID:10362364, GO:0007131=PMID:10362364} Q9Y620 DNA repair and recombination protein RAD54B protein 20130413 {GO:0003724=TAS, GO:0000724=IDA, GO:0015616=IDA, GO:0005634=IEA, GO:0032508=TAS, GO:0006312=TAS, GO:0005524=IEA, GO:0003678=TAS, GO:0007131=TAS} DNA duplex unwinding, double-strand break repair via homologous recombination, mitotic recombination, reciprocal meiotic recombination nucleus ATP binding, DNA helicase activity, DNA translocase activity, RNA helicase activity Human RAD54L GOC UniProtKB {GO:0005515=PMID:22153077, GO:0051276=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0004386=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006310=PMID:8805304, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0000733=PMID:22705370, GO:0036310=PMID:22705370, GO:0006281=PMID:8805304, GO:0007126=PMID:8805304, GO:0000724=GO_REF:0000019, GO:0010212=GO_REF:0000019} Q92698 DNA repair and recombination protein RAD54-like protein 20130413 {GO:0005515=IPI, GO:0051276=IEA, GO:0042493=IEA, GO:0004386=IEA, GO:0005634=IEA, GO:0006310=TAS, GO:0003677=IEA, GO:0005524=IEA, GO:0000733=IDA, GO:0036310=IDA, GO:0006281=TAS, GO:0007126=TAS, GO:0000724=IEA, GO:0010212=IEA} DNA recombination, DNA repair, DNA strand renaturation, chromosome organization, double-strand break repair via homologous recombination, meiosis, response to drug, response to ionizing radiation nucleus ATP binding, DNA binding, annealing helicase activity, helicase activity, protein binding Human RAD54L2 UniProtKB UniProtKB {GO:0003712=GO_REF:0000019, GO:0019901=GO_REF:0000019, GO:0004386=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000037} Q9Y4B4 Helicase ARIP4 protein 20130413 {GO:0003712=IEA, GO:0019901=IEA, GO:0004386=IEA, GO:0005634=IEA, GO:0005524=IEA, GO:0003677=IEA} nucleus ATP binding, DNA binding, helicase activity, protein kinase binding, transcription cofactor activity Human UniProtKB-SubCell:SL-0191 RAD9A HPA UniProtKB {GO:0005515=PMID:19464297, GO:0008408=PMID:10713044, GO:0017124=PMID:11971963, GO:0030896=GO_REF:0000002, GO:0043065=GO_REF:0000019, GO:0042826=PMID:10846170, GO:0019901=PMID:12628935, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0071479=PMID:21659603, GO:0006974=PMID:9872989, GO:0006260=Reactome:REACT_6769, GO:0005737=GO_REF:0000019, GO:0006281=GO_REF:0000037, GO:0008853=GO_REF:0000003, GO:0000076=PMID:8943031, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_6729, GO:0000077=PMID:21659603, GO:0019899=PMID:15326225} Q99638 Cell cycle checkpoint control protein RAD9A protein 20080205 {GO:0005515=IPI, GO:0008408=IDA, GO:0017124=IPI, GO:0030896=IEA, GO:0043065=IEA, GO:0042826=IPI, GO:0019901=IPI, GO:0005730=IDA, GO:0005634=IDA, GO:0071479=IDA, GO:0006974=IDA, GO:0006260=TAS, GO:0005737=IEA, GO:0006281=IEA, GO:0008853=IEA, GO:0000076=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0000077=IMP, GO:0019899=IPI} DNA damage checkpoint, DNA repair, DNA replication, DNA replication checkpoint, cell cycle checkpoint, cellular response to ionizing radiation, positive regulation of apoptotic process, response to DNA damage stimulus checkpoint clamp complex, cytoplasm, nucleolus, nucleoplasm, nucleus 3'-5' exonuclease activity, SH3 domain binding, enzyme binding, exodeoxyribonuclease III activity, histone deacetylase binding, protein binding, protein kinase binding NOT Human RAD9B Reactome UniProtKB {GO:0006260=Reactome:REACT_6769, GO:0005515=PMID:14500360, GO:0030896=GO_REF:0000002, GO:0006281=GO_REF:0000002, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_6729, GO:0000077=GO_REF:0000002} Q6WBX8 Cell cycle checkpoint control protein RAD9B protein 20130301 {GO:0006260=TAS, GO:0005515=IPI, GO:0030896=IEA, GO:0006281=IEA, GO:0000075=TAS, GO:0005654=TAS, GO:0000077=IEA} DNA damage checkpoint, DNA repair, DNA replication, cell cycle checkpoint checkpoint clamp complex, nucleoplasm protein binding Human RADIL UniProtKB UniProtKB {GO:0007165=GO_REF:0000002, GO:0007275=GO_REF:0000037, GO:0007155=GO_REF:0000037} Q96JH8 Ras-associating and dilute domain-containing protein protein 20130413 {GO:0007165=IEA, GO:0007275=IEA, GO:0007155=IEA} cell adhesion, multicellular organismal development, signal transduction Human UniProtKB-KW:KW-0217 RAE1 Reactome UniProtKB {GO:0008017=PMID:15851029, GO:0022415=Reactome:REACT_6361, GO:0005975=Reactome:REACT_474, GO:0003723=PMID:9256445, GO:0019221=Reactome:REACT_25229, GO:0005634=PMID:9370289, GO:0044281=Reactome:REACT_111217, GO:0005635=Reactome:REACT_115827, GO:0055085=Reactome:REACT_19118, GO:0010827=Reactome:REACT_6804, GO:0008645=Reactome:REACT_9441, GO:0005640=PMID:9256445, GO:0071407=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0006406=PMID:10209021, GO:0015758=Reactome:REACT_212, GO:0005643=PMID:9256445, GO:0016032=Reactome:REACT_6256, GO:0005856=PMID:9256445} P78406 mRNA export factor protein 20130301 {GO:0008017=ISS, GO:0022415=TAS, GO:0005975=TAS, GO:0003723=TAS, GO:0019221=TAS, GO:0005634=TAS, GO:0044281=TAS, GO:0005635=TAS, GO:0055085=TAS, GO:0010827=TAS, GO:0008645=TAS, GO:0005640=TAS, GO:0071407=IEA, GO:0005737=IEA, GO:0006406=TAS, GO:0015758=TAS, GO:0005643=TAS, GO:0016032=TAS, GO:0005856=TAS} carbohydrate metabolic process, cellular response to organic cyclic compound, cytokine-mediated signaling pathway, glucose transport, hexose transport, mRNA export from nucleus, regulation of glucose transport, small molecule metabolic process, transmembrane transport, viral reproduction, viral reproductive process cytoplasm, cytoskeleton, nuclear envelope, nuclear outer membrane, nuclear pore, nucleus RNA binding, microtubule binding Human RAET1E Reactome UniProtKB {GO:0006955=GO_REF:0000002, GO:0005886=Reactome:REACT_11178, GO:0016020=GO_REF:0000002, GO:0019882=GO_REF:0000002, GO:0042267=PMID:15240696, GO:0046703=PMID:15240696, GO:0042612=GO_REF:0000002, GO:0050776=Reactome:REACT_11152, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q8TD07 NKG2D ligand 4 protein 20130228 {GO:0006955=IEA, GO:0005886=TAS, GO:0016020=IEA, GO:0019882=IEA, GO:0042267=IDA, GO:0046703=IPI, GO:0042612=IEA, GO:0050776=TAS, GO:0005576=IEA, GO:0016021=IEA} antigen processing and presentation, immune response, natural killer cell mediated cytotoxicity, regulation of immune response MHC class I protein complex, extracellular region, integral to membrane, membrane, plasma membrane natural killer cell lectin-like receptor binding Human RAET1G HGNC UniProtKB {GO:0006955=GO_REF:0000002, GO:0005886=PMID:15240696, GO:0019882=GO_REF:0000002, GO:0042267=PMID:15240696, GO:0046703=PMID:15240696, GO:0042612=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q6H3X3 Retinoic acid early transcript 1G protein protein 20041123 {GO:0006955=IEA, GO:0005886=NAS, GO:0019882=IEA, GO:0042267=IDA, GO:0046703=IPI, GO:0042612=IEA, GO:0016021=IEA} antigen processing and presentation, immune response, natural killer cell mediated cytotoxicity MHC class I protein complex, integral to membrane, plasma membrane natural killer cell lectin-like receptor binding Human RAF1 BHF-UCL UniProtKB {GO:0005515=PMID:10523642, GO:2000145=PMID:21779496, GO:0042802=PMID:22169110, GO:0007507=GO_REF:0000019, GO:0034220=Reactome:REACT_25300, GO:0007173=Reactome:REACT_9417, GO:0000165=Reactome:REACT_634, GO:0007411=Reactome:REACT_18266, GO:0004709=GO_REF:0000019, GO:0017016=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0031434=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0042060=PMID:15943972, GO:0045595=PMID:21779496, GO:0008286=Reactome:REACT_498, GO:0008285=PMID:9765203, GO:0005886=Reactome:REACT_20631, GO:0035023=PMID:16649144, GO:0008283=PMID:8063729, GO:0007264=Reactome:REACT_12077, GO:0007268=Reactome:REACT_13685, GO:0005634=GO_REF:0000039, GO:0005741=PMID:8929532, GO:0007265=Reactome:REACT_12033, GO:0046872=GO_REF:0000037, GO:0031143=GO_REF:0000019, GO:0005829=Reactome:REACT_160256, GO:0035556=GO_REF:0000002, GO:0007190=PMID:15385642, GO:0033138=PMID:19667065, GO:0005737=GO_REF:0000024, GO:0000186=Reactome:REACT_12005, GO:0031333=PMID:19667065, GO:0007010=GO_REF:0000019, GO:0043154=PMID:21779496, GO:0001666=GO_REF:0000019, GO:0043066=PMID:19667065, GO:0048011=Reactome:REACT_11061, GO:0006915=PMID:8929532, GO:0042981=PMID:21779496, GO:0005524=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0007165=PMID:8063729, GO:0004672=PMID:8929532, GO:0004674=PMID:19667065, GO:0007596=Reactome:REACT_604, GO:0006468=PMID:8063729, GO:0005057=GO_REF:0000002} P04049 RAF proto-oncogene serine/threonine-protein kinase protein 20110504 {GO:0005515=IPI, GO:2000145=TAS, GO:0042802=IPI, GO:0007507=IEA, GO:0034220=TAS, GO:0007173=TAS, GO:0000165=TAS, GO:0007411=TAS, GO:0004709=IEA, GO:0017016=IEA, GO:0046982=IEA, GO:0031434=IEA, GO:0030168=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0042060=TAS, GO:0045595=TAS, GO:0008286=TAS, GO:0008285=IDA, GO:0005886=TAS, GO:0035023=TAS, GO:0008283=TAS, GO:0007264=TAS, GO:0007268=TAS, GO:0005634=IEA, GO:0005741=TAS, GO:0007265=TAS, GO:0046872=IEA, GO:0031143=IEA, GO:0005829=TAS, GO:0035556=IEA, GO:0007190=NAS, GO:0033138=IDA, GO:0005737=ISS, GO:0000186=TAS, GO:0031333=IDA, GO:0007010=IEA, GO:0043154=TAS, GO:0001666=IEA, GO:0043066=IDA, GO:0048011=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0005524=IEA, GO:0055085=TAS, GO:0007165=TAS, GO:0004672=TAS, GO:0004674=IDA, GO:0007596=TAS, GO:0006468=TAS, GO:0005057=IEA} MAPK cascade, Ras protein signal transduction, activation of MAPKK activity, activation of adenylate cyclase activity, apoptotic process, axon guidance, blood coagulation, cell proliferation, cytoskeleton organization, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, heart development, innate immune response, insulin receptor signaling pathway, intracellular signal transduction, ion transmembrane transport, negative regulation of apoptotic process, negative regulation of cell proliferation, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of protein complex assembly, neurotrophin TRK receptor signaling pathway, platelet activation, positive regulation of peptidyl-serine phosphorylation, protein phosphorylation, regulation of Rho protein signal transduction, regulation of apoptotic process, regulation of cell differentiation, regulation of cell motility, response to hypoxia, signal transduction, small GTPase mediated signal transduction, synaptic transmission, transmembrane transport, wound healing cytoplasm, cytosol, mitochondrial outer membrane, nucleus, plasma membrane, pseudopodium ATP binding, MAP kinase kinase kinase activity, Ras GTPase binding, identical protein binding, metal ion binding, mitogen-activated protein kinase kinase binding, protein binding, protein heterodimerization activity, protein kinase activity, protein serine/threonine kinase activity, receptor signaling protein activity Human UniProtKB:Q9ESN9 RAG1 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0004842=GO_REF:0000024, GO:0033077=GO_REF:0000024, GO:0033151=GO_REF:0000024, GO:0002331=GO_REF:0000024, GO:0016881=GO_REF:0000002, GO:0070244=GO_REF:0000019, GO:0016788=GO_REF:0000002, GO:0006310=PMID:9630231, GO:0005634=GO_REF:0000024, GO:0003677=PMID:9630231, GO:0042803=GO_REF:0000024, GO:0046872=GO_REF:0000024, GO:0051865=GO_REF:0000024, GO:0043565=GO_REF:0000024, GO:0042393=GO_REF:0000024, GO:0006955=PMID:9630231, GO:0004519=GO_REF:0000024, GO:0030183=GO_REF:0000024, GO:0008270=GO_REF:0000024, GO:0043154=GO_REF:0000019, GO:0010390=GO_REF:0000024} P15918 V(D)J recombination-activating protein 1 protein 20130415 {GO:0005515=IPI, GO:0004842=ISS, GO:0033077=ISS, GO:0033151=ISS, GO:0002331=ISS, GO:0016881=IEA, GO:0070244=IEA, GO:0016788=IEA, GO:0006310=TAS, GO:0005634=ISS, GO:0003677=TAS, GO:0042803=ISS, GO:0046872=ISS, GO:0051865=ISS, GO:0043565=ISS, GO:0042393=ISS, GO:0006955=TAS, GO:0004519=ISS, GO:0030183=ISS, GO:0008270=ISS, GO:0043154=IEA, GO:0010390=ISS} B cell differentiation, DNA recombination, T cell differentiation in thymus, V(D)J recombination, histone monoubiquitination, immune response, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of thymocyte apoptotic process, pre-B cell allelic exclusion, protein autoubiquitination nucleus DNA binding, acid-amino acid ligase activity, endonuclease activity, histone binding, hydrolase activity, acting on ester bonds, metal ion binding, protein binding, protein homodimerization activity, sequence-specific DNA binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:P16333 RAG2 UniProtKB UniProtKB {GO:0002358=GO_REF:0000019, GO:0033077=GO_REF:0000024, GO:0046622=GO_REF:0000019, GO:0002331=GO_REF:0000024, GO:0033151=GO_REF:0000024, GO:0043325=GO_REF:0000024, GO:0080025=GO_REF:0000024, GO:0005547=GO_REF:0000024, GO:0005546=GO_REF:0000024, GO:0016445=GO_REF:0000029, GO:0005634=GO_REF:0000029, GO:0035064=GO_REF:0000024, GO:0003677=GO_REF:0000029, GO:0004519=GO_REF:0000029, GO:0003682=GO_REF:0000024, GO:0030183=GO_REF:0000024, GO:0002360=GO_REF:0000019, GO:0008270=GO_REF:0000024, GO:0035091=GO_REF:0000024, GO:0002326=GO_REF:0000019, GO:0016568=GO_REF:0000037} P55895 V(D)J recombination-activating protein 2 protein 20100210 {GO:0002358=IEA, GO:0033077=ISS, GO:0046622=IEA, GO:0002331=ISS, GO:0033151=ISS, GO:0043325=ISS, GO:0080025=ISS, GO:0005547=ISS, GO:0005546=ISS, GO:0016445=NAS, GO:0005634=NAS, GO:0035064=ISS, GO:0003677=NAS, GO:0004519=NAS, GO:0003682=ISS, GO:0030183=ISS, GO:0002360=IEA, GO:0008270=ISS, GO:0035091=ISS, GO:0002326=IEA, GO:0016568=IEA} B cell differentiation, B cell homeostatic proliferation, B cell lineage commitment, T cell differentiation in thymus, T cell lineage commitment, V(D)J recombination, chromatin modification, positive regulation of organ growth, pre-B cell allelic exclusion, somatic diversification of immunoglobulins nucleus DNA binding, chromatin binding, endonuclease activity, methylated histone residue binding, phosphatidylinositol binding, phosphatidylinositol-3,4,5-trisphosphate binding, phosphatidylinositol-3,4-bisphosphate binding, phosphatidylinositol-3,5-bisphosphate binding, phosphatidylinositol-4,5-bisphosphate binding, zinc ion binding Human UniProtKB:P21784 RAI1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0001501=GO_REF:0000019, GO:0040015=GO_REF:0000019, GO:0006357=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000039} Q7Z5J4 Retinoic acid-induced protein 1 protein 20130413 {GO:0005737=IEA, GO:0001501=IEA, GO:0040015=IEA, GO:0006357=IEA, GO:0008270=IEA, GO:0005634=IEA} negative regulation of multicellular organism growth, regulation of transcription from RNA polymerase II promoter, skeletal system development cytoplasm, nucleus zinc ion binding Human UniProtKB-SubCell:SL-0086 RAI14 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0005856=GO_REF:0000039, GO:0005938=GO_REF:0000039} Q9P0K7 Ankycorbin protein 20130413 {GO:0005739=IEA, GO:0005634=IEA, GO:0005856=IEA, GO:0005938=IEA} cell cortex, cytoskeleton, mitochondrion, nucleus Human UniProtKB-SubCell:SL-0138 RAI2 IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0009790=PMID:10049581} Q9Y5P3 Retinoic acid-induced protein 2 protein 20130415 {GO:0005515=IPI, GO:0003674=ND, GO:0005575=ND, GO:0009790=NAS} embryo development cellular_component molecular_function, protein binding Human UniProtKB:Q9NRR5 RALA BHF-UCL UniProtKB {GO:0005515=PMID:10051605, GO:0005886=PMID:17875936, GO:0007264=GO_REF:0000002, GO:0003924=GO_REF:0000002, GO:0051491=PMID:10051605, GO:0030139=PMID:19306925, GO:0007265=Reactome:REACT_12033, GO:0006887=GO_REF:0000037, GO:0032154=PMID:18756269, GO:0000910=PMID:18756269, GO:0006935=PMID:10848592, GO:0051665=PMID:20005108, GO:0017157=PMID:20005108, GO:0030659=Reactome:REACT_147712, GO:0048011=Reactome:REACT_11061, GO:0009986=PMID:19306925, GO:0031532=PMID:10051605, GO:0030496=GO_REF:0000039, GO:0005525=GO_REF:0000037, GO:0007165=PMID:2550440, GO:0007049=GO_REF:0000037, GO:0016020=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0031755=PMID:19306925, GO:0016044=Reactome:REACT_11123} P11233 Ras-related protein Ral-A protein 20080914 {GO:0005515=IPI, GO:0005886=IDA, GO:0007264=IEA, GO:0003924=IEA, GO:0051491=IDA, GO:0030139=IDA, GO:0007265=TAS, GO:0006887=IEA, GO:0032154=IDA, GO:0000910=IDA, GO:0006935=TAS, GO:0051665=IDA, GO:0017157=IDA, GO:0030659=TAS, GO:0048011=TAS, GO:0009986=IDA, GO:0031532=IDA, GO:0030496=IEA, GO:0005525=IEA, GO:0007165=TAS, GO:0007049=IEA, GO:0016020=IEA, GO:0019048=IEA, GO:0031755=IDA, GO:0016044=TAS} Ras protein signal transduction, actin cytoskeleton reorganization, cell cycle, cellular membrane organization, chemotaxis, cytokinesis, exocytosis, membrane raft localization, neurotrophin TRK receptor signaling pathway, positive regulation of filopodium assembly, regulation of exocytosis, signal transduction, small GTPase mediated signal transduction, virus-host interaction cell surface, cleavage furrow, cytoplasmic vesicle membrane, endocytic vesicle, membrane, midbody, plasma membrane Edg-2 lysophosphatidic acid receptor binding, GTP binding, GTPase activity, protein binding Human RALB UniProtKB UniProtKB {GO:0005515=PMID:19166349, GO:0048011=Reactome:REACT_11061, GO:0005886=PMID:17875936, GO:0007264=GO_REF:0000002, GO:0003924=GO_REF:0000002, GO:0006915=GO_REF:0000037, GO:0030496=PMID:18756269, GO:0007265=Reactome:REACT_12033, GO:0005525=GO_REF:0000038, GO:0001928=GO_REF:0000024, GO:0000910=PMID:18756269, GO:0007165=PMID:2120779, GO:0007049=GO_REF:0000037, GO:0016020=GO_REF:0000002, GO:0060178=GO_REF:0000024} Q6ZS74 cDNA FLJ45773 fis, clone NETRP2003448, highly similar to Ras-related protein RAL-B protein 20130413 {GO:0005515=IPI, GO:0048011=TAS, GO:0005886=IDA, GO:0007264=IEA, GO:0003924=IEA, GO:0006915=IEA, GO:0030496=IDA, GO:0007265=TAS, GO:0005525=IEA, GO:0001928=ISS, GO:0000910=IDA, GO:0007165=TAS, GO:0007049=IEA, GO:0016020=IEA, GO:0060178=ISS} Ras protein signal transduction, apoptotic process, cell cycle, cytokinesis, neurotrophin TRK receptor signaling pathway, regulation of exocyst assembly, regulation of exocyst localization, signal transduction, small GTPase mediated signal transduction membrane, midbody, plasma membrane GTP binding, GTPase activity, protein binding Human UniProtKB-KW:KW-0342 RALBP1 GOC UniProtKB {GO:0005515=PMID:9422736, GO:0051056=Reactome:REACT_11051, GO:0006200=PMID:10924126, GO:0007264=Reactome:REACT_11044, GO:0032855=PMID:7673236, GO:0043087=PMID:7673236, GO:0005829=Reactome:REACT_9982, GO:0007165=PMID:7673236, GO:0048365=PMID:7673236, GO:0016020=PMID:11437348, GO:0006935=PMID:10848592, GO:0043089=PMID:7673236, GO:0006810=PMID:11437348, GO:0030675=PMID:7673236, GO:0016887=PMID:10924126, GO:0017160=PMID:7673236, GO:0005096=PMID:7673236, GO:0043492=PMID:11437348} Q15311 RalA-binding protein 1 protein 20130413 {GO:0005515=IPI, GO:0051056=TAS, GO:0006200=IDA, GO:0007264=TAS, GO:0032855=IDA, GO:0043087=IDA, GO:0005829=TAS, GO:0007165=TAS, GO:0048365=IPI, GO:0016020=IDA, GO:0006935=TAS, GO:0043089=IDA, GO:0006810=IDA, GO:0030675=IDA, GO:0016887=IDA, GO:0017160=IPI, GO:0005096=IDA, GO:0043492=IDA} ATP catabolic process, chemotaxis, positive regulation of Cdc42 GTPase activity, positive regulation of Rac GTPase activity, regulation of GTPase activity, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction, transport cytosol, membrane ATPase activity, ATPase activity, coupled to movement of substances, GTPase activator activity, Rac GTPase activator activity, Rac GTPase binding, Ral GTPase binding, protein binding Human RALGAPA1 HPA UniProtKB {GO:0043547=GO_REF:0000033, GO:0005739=GO_REF:0000052, GO:0032859=GO_REF:0000024, GO:0051056=GO_REF:0000002, GO:0006355=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0017123=GO_REF:0000024, GO:0046982=PMID:19520869, GO:0005634=GO_REF:0000024, GO:0005829=GO_REF:0000033, GO:0005096=GO_REF:0000033} Q6GYQ0 Ral GTPase-activating protein subunit alpha-1 protein 20101115 {GO:0043547=IBA, GO:0005739=IDA, GO:0032859=ISS, GO:0051056=IEA, GO:0006355=IEA, GO:0005737=IDA, GO:0017123=ISS, GO:0046982=IPI, GO:0005634=ISS, GO:0005829=IBA, GO:0005096=IBA} activation of Ral GTPase activity, positive regulation of GTPase activity, regulation of small GTPase mediated signal transduction, regulation of transcription, DNA-dependent cytoplasm, cytosol, mitochondrion, nucleus GTPase activator activity, Ral GTPase activator activity, protein heterodimerization activity Human RALGAPA2 InterPro UniProtKB {GO:0032859=GO_REF:0000024, GO:0051056=GO_REF:0000002, GO:0005737=PMID:16490346, GO:0017123=GO_REF:0000024, GO:0046982=GO_REF:0000024, GO:0032484=GO_REF:0000019, GO:0005634=GO_REF:0000002, GO:0060178=GO_REF:0000019, GO:0016044=Reactome:REACT_11123, GO:0005829=GO_REF:0000033, GO:0005096=GO_REF:0000002} Q4VXU5 Ral GTPase-activating protein subunit alpha-2 protein 20130413 {GO:0032859=ISS, GO:0051056=IEA, GO:0005737=IDA, GO:0017123=ISS, GO:0046982=ISS, GO:0032484=IEA, GO:0005634=IEA, GO:0060178=IEA, GO:0016044=TAS, GO:0005829=IBA, GO:0005096=IEA} Ral protein signal transduction, activation of Ral GTPase activity, cellular membrane organization, regulation of exocyst localization, regulation of small GTPase mediated signal transduction cytoplasm, cytosol, nucleus GTPase activator activity, Ral GTPase activator activity, protein heterodimerization activity Human InterPro:IPR027107 RALGAPB Reactome UniProtKB {GO:0032859=GO_REF:0000024, GO:0051056=GO_REF:0000002, GO:0017123=GO_REF:0000024, GO:0046982=GO_REF:0000024, GO:0032484=GO_REF:0000019, GO:0060178=GO_REF:0000019, GO:0016044=Reactome:REACT_11123, GO:0005096=GO_REF:0000002} Q86X10 Ral GTPase-activating protein subunit beta protein 20110721 {GO:0032859=ISS, GO:0051056=IEA, GO:0017123=ISS, GO:0046982=ISS, GO:0032484=IEA, GO:0060178=IEA, GO:0016044=TAS, GO:0005096=IEA} Ral protein signal transduction, activation of Ral GTPase activity, cellular membrane organization, regulation of exocyst localization, regulation of small GTPase mediated signal transduction GTPase activator activity, Ral GTPase activator activity, protein heterodimerization activity Human RALGDS UniProtKB UniProtKB {GO:0005085=GO_REF:0000038, GO:0005622=GO_REF:0000002, GO:0051056=GO_REF:0000002, GO:0048011=Reactome:REACT_11061, GO:0005083=PMID:7972015, GO:0007264=GO_REF:0000002, GO:0007265=Reactome:REACT_12033, GO:0005829=Reactome:REACT_12001} Q6PCE1 RALGDS protein protein 20130413 {GO:0005085=IEA, GO:0005622=IEA, GO:0051056=IEA, GO:0048011=TAS, GO:0005083=IDA, GO:0007264=IEA, GO:0007265=TAS, GO:0005829=TAS} Ras protein signal transduction, neurotrophin TRK receptor signaling pathway, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol, intracellular guanyl-nucleotide exchange factor activity, small GTPase regulator activity Human UniProtKB-KW:KW-0344 RALGPS1 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0035556=PMID:10747847, GO:0005085=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0005575=GO_REF:0000015} Q5JT61 Ras-specific guanine nucleotide-releasing factor RalGPS1 protein 20130413 {GO:0005622=IEA, GO:0035556=NAS, GO:0005085=IEA, GO:0005737=IEA, GO:0005543=IEA, GO:0005886=IEA, GO:0007264=IEA, GO:0005575=ND} intracellular signal transduction, small GTPase mediated signal transduction cellular_component, cytoplasm, intracellular, plasma membrane guanyl-nucleotide exchange factor activity, phospholipid binding Human InterPro:IPR001895|InterPro:IPR008937 RALGPS2 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0005085=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0007264=GO_REF:0000002} Q86X27 Ras-specific guanine nucleotide-releasing factor RalGPS2 protein 20130413 {GO:0005622=IEA, GO:0005085=IEA, GO:0005737=IEA, GO:0005543=IEA, GO:0005886=IEA, GO:0007264=IEA} small GTPase mediated signal transduction cytoplasm, intracellular, plasma membrane guanyl-nucleotide exchange factor activity, phospholipid binding Human UniProtKB-SubCell:SL-0039 RALY PINC UniProtKB {GO:0000166=GO_REF:0000002, GO:0000398=PMID:11991638, GO:0003723=GO_REF:0000037, GO:0005634=PMID:9376072, GO:0071013=PMID:11991638, GO:0003676=GO_REF:0000002} Q9UKM9 RNA-binding protein Raly protein 20050308 {GO:0000166=IEA, GO:0000398=IC, GO:0003723=IEA, GO:0005634=TAS, GO:0071013=IDA, GO:0003676=IEA} mRNA splicing, via spliceosome catalytic step 2 spliceosome, nucleus RNA binding, nucleic acid binding, nucleotide binding Human RALYL UniProtKB UniProtKB {GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0003676=GO_REF:0000002} Q86SE5 RNA-binding Raly-like protein protein 20130413 {GO:0000166=IEA, GO:0003723=IEA, GO:0003676=IEA} RNA binding, nucleic acid binding, nucleotide binding Human UniProtKB-KW:KW-0694 RAMP1 BHF-UCL UniProtKB {GO:0005515=PMID:14722252, GO:0004948=PMID:9620797, GO:0005886=PMID:18039931, GO:0031716=PMID:9620797, GO:0001525=PMID:20596610, GO:0015031=PMID:10882736, GO:0015026=GO_REF:0000019, GO:0006886=GO_REF:0000002, GO:0005615=GO_REF:0000019, GO:0043235=PMID:15613468, GO:0031623=PMID:15613468, GO:0008277=PMID:9620797, GO:0007186=GO_REF:0000019, GO:0005887=PMID:9620797, GO:0008565=PMID:10882736, GO:0006816=PMID:10882736, GO:0004872=PMID:10882736, GO:0016021=GO_REF:0000002} O60894 Receptor activity-modifying protein 1 protein 20080908 {GO:0005515=IPI, GO:0004948=IDA, GO:0005886=IDA, GO:0031716=IPI, GO:0001525=IDA, GO:0015031=IDA, GO:0015026=IEA, GO:0006886=IEA, GO:0005615=IEA, GO:0043235=IDA, GO:0031623=IDA, GO:0008277=IDA, GO:0007186=IEA, GO:0005887=TAS, GO:0008565=IDA, GO:0006816=IDA, GO:0004872=IDA, GO:0016021=IEA} G-protein coupled receptor signaling pathway, angiogenesis, calcium ion transport, intracellular protein transport, protein transport, receptor internalization, regulation of G-protein coupled receptor protein signaling pathway extracellular space, integral to membrane, integral to plasma membrane, plasma membrane, receptor complex calcitonin receptor activity, calcitonin receptor binding, coreceptor activity, protein binding, protein transporter activity, receptor activity Human RAMP2 Reactome UniProtKB {GO:0005515=PMID:20596610, GO:0035924=GO_REF:0000024, GO:2001214=GO_REF:0000019, GO:0005886=Reactome:REACT_22268, GO:0034333=PMID:18097473, GO:0002040=GO_REF:0000024, GO:0015031=PMID:10882736, GO:0005764=PMID:10882736, GO:0006886=GO_REF:0000002, GO:0032870=GO_REF:0000019, GO:0007507=GO_REF:0000024, GO:0031623=PMID:15613468, GO:0005737=PMID:10882736, GO:0070830=PMID:18097473, GO:0070831=GO_REF:0000024, GO:0006171=PMID:20074556, GO:0006816=PMID:10882736, GO:0032355=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:0001525=PMID:20596610, GO:0015026=GO_REF:0000024, GO:0045766=GO_REF:0000024, GO:0043235=PMID:15613468, GO:0005905=PMID:10882736, GO:0008277=GO_REF:0000002, GO:0007186=GO_REF:0000019, GO:0005887=PMID:9620797, GO:0008565=PMID:10882736, GO:0008217=GO_REF:0000024, GO:0032570=GO_REF:0000019, GO:0016021=GO_REF:0000002, GO:0097084=GO_REF:0000024, GO:2000352=PMID:18097473, GO:0001570=PMID:16964401, GO:0043116=PMID:18097473} O60895 Receptor activity-modifying protein 2 protein 20090511 {GO:0005515=IPI, GO:0035924=ISS, GO:2001214=IEA, GO:0005886=TAS, GO:0034333=IDA, GO:0002040=ISS, GO:0015031=IDA, GO:0005764=TAS, GO:0006886=IEA, GO:0032870=IEA, GO:0007507=ISS, GO:0031623=IDA, GO:0005737=IDA, GO:0070830=IDA, GO:0070831=ISS, GO:0006171=IDA, GO:0006816=IDA, GO:0032355=IEA, GO:0001666=IEA, GO:0007565=IEA, GO:0001525=IDA, GO:0015026=ISS, GO:0045766=ISS, GO:0043235=IDA, GO:0005905=TAS, GO:0008277=IEA, GO:0007186=IEA, GO:0005887=TAS, GO:0008565=IDA, GO:0008217=ISS, GO:0032570=IEA, GO:0016021=IEA, GO:0097084=ISS, GO:2000352=IDA, GO:0001570=IMP, GO:0043116=IDA} G-protein coupled receptor signaling pathway, adherens junction assembly, angiogenesis, basement membrane assembly, cAMP biosynthetic process, calcium ion transport, cellular response to hormone stimulus, cellular response to vascular endothelial growth factor stimulus, female pregnancy, heart development, intracellular protein transport, negative regulation of endothelial cell apoptotic process, negative regulation of vascular permeability, positive regulation of angiogenesis, positive regulation of vasculogenesis, protein transport, receptor internalization, regulation of G-protein coupled receptor protein signaling pathway, regulation of blood pressure, response to estradiol stimulus, response to hypoxia, response to progesterone stimulus, sprouting angiogenesis, tight junction assembly, vascular smooth muscle cell development, vasculogenesis coated pit, cytoplasm, integral to membrane, integral to plasma membrane, lysosome, plasma membrane, receptor complex coreceptor activity, protein binding, protein transporter activity Human RAMP3 Reactome UniProtKB {GO:0005515=PMID:15613468, GO:0005886=Reactome:REACT_22268, GO:0009986=PMID:10882736, GO:0015026=GO_REF:0000019, GO:0015031=PMID:10882736, GO:0006886=GO_REF:0000002, GO:0005764=PMID:15613468, GO:0031623=PMID:15613468, GO:0043235=PMID:15613468, GO:0008277=GO_REF:0000002, GO:0007186=GO_REF:0000019, GO:0005887=PMID:9620797, GO:0008565=PMID:10882736, GO:0001921=PMID:15613468, GO:0006816=PMID:10882736, GO:0016021=GO_REF:0000002} O60896 Receptor activity-modifying protein 3 protein 20090511 {GO:0005515=IPI, GO:0005886=TAS, GO:0009986=IDA, GO:0015026=IEA, GO:0015031=IDA, GO:0006886=IEA, GO:0005764=IDA, GO:0031623=IDA, GO:0043235=IDA, GO:0008277=IEA, GO:0007186=IEA, GO:0005887=TAS, GO:0008565=IDA, GO:0001921=IDA, GO:0006816=IDA, GO:0016021=IEA} G-protein coupled receptor signaling pathway, calcium ion transport, intracellular protein transport, positive regulation of receptor recycling, protein transport, receptor internalization, regulation of G-protein coupled receptor protein signaling pathway cell surface, integral to membrane, integral to plasma membrane, lysosome, plasma membrane, receptor complex coreceptor activity, protein binding, protein transporter activity Human RAN BHF-UCL UniProtKB {GO:0005515=PMID:18617507, GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0007264=GO_REF:0000002, GO:0019058=Reactome:REACT_6167, GO:0003924=PMID:10400640, GO:0044281=Reactome:REACT_111217, GO:0050681=PMID:15572661, GO:0006886=GO_REF:0000002, GO:0032092=PMID:16449645, GO:0005829=Reactome:REACT_12608, GO:0006405=GO_REF:0000029, GO:0005737=PMID:1961752, GO:0005643=PMID:8421051, GO:0006611=PMID:16449645, GO:0016032=Reactome:REACT_6256, GO:0007052=PMID:10408446, GO:0000785=PMID:1961752, GO:0042470=GO_REF:0000039, GO:0003713=PMID:15572661, GO:0006259=PMID:8421051, GO:0005525=PMID:1961752, GO:0006913=GO_REF:0000002, GO:0007165=PMID:7603572, GO:0007067=PMID:8421051, GO:0003682=PMID:1961752, GO:0005654=Reactome:REACT_147724, GO:0045893=PMID:15572661, GO:0075733=Reactome:REACT_6296, GO:0030521=PMID:15572661, GO:0051301=GO_REF:0000037} P62826 GTP-binding nuclear protein Ran protein 20111214 {GO:0005515=IPI, GO:0022415=TAS, GO:0010467=TAS, GO:0007264=IEA, GO:0019058=TAS, GO:0003924=TAS, GO:0044281=TAS, GO:0050681=NAS, GO:0006886=IEA, GO:0032092=IDA, GO:0005829=TAS, GO:0006405=NAS, GO:0005737=IDA, GO:0005643=NAS, GO:0006611=IDA, GO:0016032=TAS, GO:0007052=TAS, GO:0000785=IDA, GO:0042470=IEA, GO:0003713=NAS, GO:0006259=TAS, GO:0005525=IDA, GO:0006913=IEA, GO:0007165=TAS, GO:0007067=TAS, GO:0003682=TAS, GO:0005654=TAS, GO:0045893=NAS, GO:0075733=TAS, GO:0030521=NAS, GO:0051301=IEA} DNA metabolic process, RNA export from nucleus, androgen receptor signaling pathway, cell division, gene expression, intracellular protein transport, intracellular transport of viral material, mitosis, mitotic spindle organization, nucleocytoplasmic transport, positive regulation of protein binding, positive regulation of transcription, DNA-dependent, protein export from nucleus, signal transduction, small GTPase mediated signal transduction, small molecule metabolic process, viral infectious cycle, viral reproduction, viral reproductive process chromatin, cytoplasm, cytosol, melanosome, nuclear pore, nucleoplasm GTP binding, GTPase activity, androgen receptor binding, chromatin binding, protein binding, transcription coactivator activity Human RANBP1 Reactome UniProtKB {GO:0022415=Reactome:REACT_6361, GO:0005813=GO_REF:0000019, GO:0046907=GO_REF:0000002, GO:0046604=GO_REF:0000019, GO:0005634=PMID:16130169, GO:0005635=Reactome:REACT_9478, GO:0007165=PMID:16130169, GO:0005737=PMID:16130169, GO:0008536=PMID:7882974, GO:0016032=Reactome:REACT_6256, GO:0007051=GO_REF:0000019, GO:0005092=PMID:7616957, GO:0005096=GO_REF:0000037} P43487 Ran-specific GTPase-activating protein protein 20130213 {GO:0022415=TAS, GO:0005813=IEA, GO:0046907=IEA, GO:0046604=IEA, GO:0005634=TAS, GO:0005635=TAS, GO:0007165=TAS, GO:0005737=TAS, GO:0008536=TAS, GO:0016032=TAS, GO:0007051=IEA, GO:0005092=TAS, GO:0005096=IEA} intracellular transport, positive regulation of mitotic centrosome separation, signal transduction, spindle organization, viral reproduction, viral reproductive process centrosome, cytoplasm, nuclear envelope, nucleus GDP-dissociation inhibitor activity, GTPase activator activity, Ran GTPase binding Human RANBP10 UniProtKB UniProtKB {GO:0005881=GO_REF:0000019, GO:0008536=GO_REF:0000019, GO:0048487=GO_REF:0000019, GO:0000226=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0005087=GO_REF:0000019, GO:0005829=GO_REF:0000039} Q6VN20 Ran-binding protein 10 protein 20130413 {GO:0005881=IEA, GO:0008536=IEA, GO:0048487=IEA, GO:0000226=IEA, GO:0005634=IEA, GO:0005087=IEA, GO:0005829=IEA} microtubule cytoskeleton organization cytoplasmic microtubule, cytosol, nucleus Ran GTPase binding, Ran guanyl-nucleotide exchange factor activity, beta-tubulin binding Human UniProtKB-SubCell:SL-0091 RANBP17 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005643=PMID:11024021, GO:0008565=GO_REF:0000002, GO:0051028=GO_REF:0000037, GO:0006606=PMID:11024021, GO:0005525=PMID:11024021, GO:0006886=GO_REF:0000002} Q9H2T7 Ran-binding protein 17 protein 20021218 {GO:0005737=IEA, GO:0005643=NAS, GO:0008565=IEA, GO:0051028=IEA, GO:0006606=NAS, GO:0005525=NAS, GO:0006886=IEA} intracellular protein transport, mRNA transport, protein import into nucleus cytoplasm, nuclear pore GTP binding, protein transporter activity Human RANBP2 Reactome UniProtKB {GO:0005515=PMID:22155184, GO:0022415=Reactome:REACT_6361, GO:0000236=Reactome:REACT_682, GO:0016874=GO_REF:0000037, GO:0019221=Reactome:REACT_25229, GO:0044281=Reactome:REACT_111217, GO:0006606=PMID:7603572, GO:0005829=Reactome:REACT_150414, GO:0008645=Reactome:REACT_9441, GO:0015758=Reactome:REACT_212, GO:0005643=PMID:17098863, GO:0006457=GO_REF:0000037, GO:0008536=PMID:7603572, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6256, GO:0031965=PMID:11839768, GO:0044615=PMID:11839768, GO:0005975=Reactome:REACT_474, GO:0016925=PMID:17264123, GO:0003755=GO_REF:0000003, GO:0046907=GO_REF:0000002, GO:0055085=Reactome:REACT_19118, GO:0010827=Reactome:REACT_6804, GO:0008270=GO_REF:0000002, GO:0051028=GO_REF:0000037, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0042405=PMID:11839768} P49792 E3 SUMO-protein ligase RanBP2 protein 20130301 {GO:0005515=IPI, GO:0022415=TAS, GO:0000236=TAS, GO:0016874=IEA, GO:0019221=TAS, GO:0044281=TAS, GO:0006606=TAS, GO:0005829=TAS, GO:0008645=TAS, GO:0015758=TAS, GO:0005643=IDA, GO:0006457=IEA, GO:0008536=TAS, GO:0000087=TAS, GO:0016032=TAS, GO:0031965=IDA, GO:0044615=IDA, GO:0005975=TAS, GO:0016925=IDA, GO:0003755=IEA, GO:0046907=IEA, GO:0055085=TAS, GO:0010827=TAS, GO:0008270=IEA, GO:0051028=IEA, GO:0000278=TAS, GO:0000090=TAS, GO:0042405=IDA} M phase of mitotic cell cycle, carbohydrate metabolic process, cytokine-mediated signaling pathway, glucose transport, hexose transport, intracellular transport, mRNA transport, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, protein folding, protein import into nucleus, protein sumoylation, regulation of glucose transport, small molecule metabolic process, transmembrane transport, viral reproduction, viral reproductive process cytosol, nuclear inclusion body, nuclear membrane, nuclear pore, nuclear pore nuclear basket Ran GTPase binding, ligase activity, peptidyl-prolyl cis-trans isomerase activity, protein binding, zinc ion binding Human RANBP3 HPA UniProtKB {GO:0005515=PMID:11932251, GO:0005737=GO_REF:0000039, GO:0008536=PMID:9637251, GO:0005730=GO_REF:0000052, GO:0070412=PMID:19289081, GO:0005634=GO_REF:0000052, GO:0046907=GO_REF:0000002, GO:0015031=GO_REF:0000037} Q9H6Z4 Ran-binding protein 3 protein 20120912 {GO:0005515=IPI, GO:0005737=IEA, GO:0008536=TAS, GO:0005730=IDA, GO:0070412=IPI, GO:0005634=IDA, GO:0046907=IEA, GO:0015031=IEA} intracellular transport, protein transport cytoplasm, nucleolus, nucleus R-SMAD binding, Ran GTPase binding, protein binding NOT Human RANBP6 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0015031=GO_REF:0000037} O60518 Ran-binding protein 6 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0005634=IEA, GO:0015031=IEA} protein transport cytoplasm, nucleus protein binding Human UniProtKB:Q76353 RANBP9 IntAct UniProtKB {GO:0005515=PMID:21382349, GO:0006461=PMID:9817760, GO:0007411=Reactome:REACT_18266, GO:0005875=PMID:9817760, GO:0007020=PMID:12220523, GO:0008536=PMID:9817760, GO:0005634=PMID:12220523, GO:0019899=PMID:17087506, GO:0005829=Reactome:REACT_22215} Q96S59 Ran-binding protein 9 protein 20130415 {GO:0005515=IPI, GO:0006461=TAS, GO:0007411=TAS, GO:0005875=TAS, GO:0007020=NAS, GO:0008536=TAS, GO:0005634=IDA, GO:0019899=IPI, GO:0005829=TAS} axon guidance, microtubule nucleation, protein complex assembly cytosol, microtubule associated complex, nucleus Ran GTPase binding, enzyme binding, protein binding Human UniProtKB:P36873-2 RANGAP1 GOC UniProtKB {GO:0005515=PMID:17000644, GO:0000236=Reactome:REACT_682, GO:0048471=GO_REF:0000019, GO:0031965=GO_REF:0000039, GO:0032853=PMID:7878053, GO:0005829=Reactome:REACT_150414, GO:0046826=PMID:16449645, GO:0005098=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0000922=GO_REF:0000039, GO:0005737=PMID:8978815, GO:0005643=PMID:8978815, GO:0000087=Reactome:REACT_910, GO:0000777=GO_REF:0000039, GO:0000776=PMID:17363900, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275} P46060 Ran GTPase-activating protein 1 protein 20130413 {GO:0005515=IPI, GO:0000236=TAS, GO:0048471=IEA, GO:0031965=IEA, GO:0032853=TAS, GO:0005829=TAS, GO:0046826=IDA, GO:0005098=IEA, GO:0007165=IEA, GO:0000922=IEA, GO:0005737=TAS, GO:0005643=TAS, GO:0000087=TAS, GO:0000777=IEA, GO:0000776=IDA, GO:0000278=TAS, GO:0000090=TAS} M phase of mitotic cell cycle, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, negative regulation of protein export from nucleus, positive regulation of Ran GTPase activity, signal transduction condensed chromosome kinetochore, cytoplasm, cytosol, kinetochore, nuclear membrane, nuclear pore, perinuclear region of cytoplasm, spindle pole Ran GTPase activator activity, protein binding Human RANGRF BHF-UCL UniProtKB {GO:0005085=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0014704=PMID:18184654, GO:0042391=PMID:18184654, GO:0005634=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0044325=PMID:18184654} Q9HD47 Ran guanine nucleotide release factor protein 20120518 {GO:0005085=IEA, GO:0005737=IEA, GO:0014704=ISS, GO:0042391=IDA, GO:0005634=IEA, GO:0015031=IEA, GO:0044325=IPI} protein transport, regulation of membrane potential cytoplasm, intercalated disc, nucleus guanyl-nucleotide exchange factor activity, ion channel binding Human UniProtKB:Q9JIB0 RAP1A IntAct UniProtKB {GO:0005515=PMID:15569673, GO:0048011=Reactome:REACT_11061, GO:0005886=Reactome:REACT_23931, GO:0007264=GO_REF:0000019, GO:0003924=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0044281=Reactome:REACT_111217, GO:0005525=GO_REF:0000037, GO:0005829=Reactome:REACT_12037, GO:0007165=PMID:2642744, GO:0000186=Reactome:REACT_12005, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0007596=Reactome:REACT_604, GO:0017016=GO_REF:0000019, GO:0032045=GO_REF:0000019} P62834 Ras-related protein Rap-1A protein 20130415 {GO:0005515=IPI, GO:0048011=TAS, GO:0005886=TAS, GO:0007264=IEA, GO:0003924=IEA, GO:0030168=TAS, GO:0044281=TAS, GO:0005525=IEA, GO:0005829=TAS, GO:0007165=TAS, GO:0000186=TAS, GO:0006112=TAS, GO:0050796=TAS, GO:0007596=TAS, GO:0017016=IEA, GO:0032045=IEA} activation of MAPKK activity, blood coagulation, energy reserve metabolic process, neurotrophin TRK receptor signaling pathway, platelet activation, regulation of insulin secretion, signal transduction, small GTPase mediated signal transduction, small molecule metabolic process cytosol, guanyl-nucleotide exchange factor complex, plasma membrane GTP binding, GTPase activity, Ras GTPase binding, protein binding Human UniProtKB:Q8WWW0-2 RAP1B LIFEdb UniProtKB {GO:0005515=PMID:18660803, GO:0005886=Reactome:REACT_23931, GO:0007264=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:0003924=PMID:18309292, GO:2000114=PMID:20332120, GO:0030168=Reactome:REACT_798, GO:0044281=Reactome:REACT_111217, GO:0005525=PMID:18309292, GO:0005829=GO_REF:0000039, GO:0005622=GO_REF:0000054, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0016020=PMID:2123345, GO:0007596=Reactome:REACT_604, GO:0005911=PMID:20332120, GO:0019003=PMID:18309292, GO:0017016=GO_REF:0000019, GO:0032045=GO_REF:0000019} P61224 Ras-related protein Rap-1b protein 20100607 {GO:0005515=IPI, GO:0005886=TAS, GO:0007264=IEA, GO:0008283=IEA, GO:0003924=IDA, GO:2000114=IMP, GO:0030168=TAS, GO:0044281=TAS, GO:0005525=IDA, GO:0005829=IEA, GO:0005622=IDA, GO:0006112=TAS, GO:0050796=TAS, GO:0016020=TAS, GO:0007596=TAS, GO:0005911=IDA, GO:0019003=IDA, GO:0017016=IEA, GO:0032045=IEA} blood coagulation, cell proliferation, energy reserve metabolic process, platelet activation, regulation of establishment of cell polarity, regulation of insulin secretion, small GTPase mediated signal transduction, small molecule metabolic process cell-cell junction, cytosol, guanyl-nucleotide exchange factor complex, intracellular, membrane, plasma membrane GDP binding, GTP binding, GTPase activity, Ras GTPase binding, protein binding Human RAP1GAP InterPro UniProtKB {GO:0005515=PMID:20877310, GO:0051056=GO_REF:0000002, GO:0003924=PMID:10476970, GO:0042803=PMID:18309292, GO:0005829=Reactome:REACT_23811, GO:0006184=PMID:10476970, GO:0043547=PMID:1904317, GO:0007165=PMID:10476970, GO:0000139=GO_REF:0000039, GO:0016020=PMID:10476970, GO:0017016=PMID:18309292, GO:0032318=PMID:18309292, GO:0030695=GO_REF:0000002, GO:0005096=GO_REF:0000002} Q5T3T1 Rap1 GTPase-activating protein 1 protein 20130413 {GO:0005515=IPI, GO:0051056=IEA, GO:0003924=NAS, GO:0042803=IPI, GO:0005829=TAS, GO:0006184=NAS, GO:0043547=TAS, GO:0007165=NAS, GO:0000139=IEA, GO:0016020=IDA, GO:0017016=IPI, GO:0032318=IDA, GO:0030695=IEA, GO:0005096=IEA} GTP catabolic process, positive regulation of GTPase activity, regulation of Ras GTPase activity, regulation of small GTPase mediated signal transduction, signal transduction Golgi membrane, cytosol, membrane GTPase activator activity, GTPase activity, GTPase regulator activity, Ras GTPase binding, protein binding, protein homodimerization activity Human InterPro:IPR003109 RAP1GAP2 Reactome UniProtKB {GO:0051056=GO_REF:0000002, GO:0005813=PMID:21399614, GO:0048471=GO_REF:0000039, GO:0005829=Reactome:REACT_23924, GO:0005096=GO_REF:0000037} Q684P5 Rap1 GTPase-activating protein 2 protein 20100720 {GO:0051056=IEA, GO:0005813=IDA, GO:0048471=IEA, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction centrosome, cytosol, perinuclear region of cytoplasm GTPase activator activity Human RAP1GDS1 GOC UniProtKB {GO:0043547=PMID:1549351, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0005096=PMID:1549351} P52306 Rap1 GTPase-GDP dissociation stimulator 1 protein 20130413 {GO:0043547=NAS, GO:0008150=ND, GO:0005575=ND, GO:0005096=NAS} biological_process, positive regulation of GTPase activity cellular_component GTPase activator activity Human RAP2A MGI UniProtKB {GO:0005515=PMID:15342639, GO:0030336=GO_REF:0000019, GO:0032486=GO_REF:0000024, GO:0031532=PMID:15342639, GO:0007264=GO_REF:0000002, GO:0003924=PMID:1900290, GO:0005525=GO_REF:0000037, GO:0045184=PMID:19061864, GO:0005829=GO_REF:0000019, GO:0046328=PMID:14966141, GO:0048814=PMID:20159449, GO:0016020=GO_REF:0000002, GO:0034613=PMID:15342639, GO:0055037=PMID:19061864, GO:0055038=PMID:19061864, GO:0031954=PMID:15342639} P10114 Ras-related protein Rap-2a protein 20100607 {GO:0005515=IPI, GO:0030336=IEA, GO:0032486=ISS, GO:0031532=IDA, GO:0007264=IEA, GO:0003924=IDA, GO:0005525=IEA, GO:0045184=IDA, GO:0005829=IEA, GO:0046328=IDA, GO:0048814=IDA, GO:0016020=IEA, GO:0034613=IDA, GO:0055037=IDA, GO:0055038=IDA, GO:0031954=IDA} Rap protein signal transduction, actin cytoskeleton reorganization, cellular protein localization, establishment of protein localization, negative regulation of cell migration, positive regulation of protein autophosphorylation, regulation of JNK cascade, regulation of dendrite morphogenesis, small GTPase mediated signal transduction cytosol, membrane, recycling endosome, recycling endosome membrane GTP binding, GTPase activity, protein binding Human RAP2B PINC UniProtKB {GO:0007165=PMID:2118648, GO:0030336=GO_REF:0000019, GO:0032486=GO_REF:0000024, GO:0061097=GO_REF:0000024, GO:0019904=GO_REF:0000019, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0055038=GO_REF:0000024, GO:0031954=GO_REF:0000019, GO:0005829=GO_REF:0000019} P61225 Ras-related protein Rap-2b protein 20061109 {GO:0007165=TAS, GO:0030336=IEA, GO:0032486=ISS, GO:0061097=ISS, GO:0019904=IEA, GO:0003924=IEA, GO:0005525=IEA, GO:0055038=ISS, GO:0031954=IEA, GO:0005829=IEA} Rap protein signal transduction, negative regulation of cell migration, positive regulation of protein autophosphorylation, regulation of protein tyrosine kinase activity, signal transduction cytosol, recycling endosome membrane GTP binding, GTPase activity, protein domain specific binding Human RAP2C UniProtKB UniProtKB {GO:0030336=GO_REF:0000024, GO:0032486=GO_REF:0000024, GO:0061097=GO_REF:0000024, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0055038=GO_REF:0000024, GO:0031954=GO_REF:0000024, GO:0005829=GO_REF:0000019} Q9Y3L5 Ras-related protein Rap-2c protein 20100915 {GO:0030336=ISS, GO:0032486=ISS, GO:0061097=ISS, GO:0003924=IEA, GO:0005525=IEA, GO:0055038=ISS, GO:0031954=ISS, GO:0005829=IEA} Rap protein signal transduction, negative regulation of cell migration, positive regulation of protein autophosphorylation, regulation of protein tyrosine kinase activity cytosol, recycling endosome membrane GTP binding, GTPase activity Human UniProtKB:Q8BU31 RAPGEF1 UniProtKB UniProtKB {GO:0005515=PMID:19380743, GO:0051056=GO_REF:0000002, GO:0048011=Reactome:REACT_11061, GO:0017124=GO_REF:0000037, GO:0001568=GO_REF:0000019, GO:0007264=GO_REF:0000002, GO:0005829=Reactome:REACT_23785, GO:0005085=GO_REF:0000038, GO:0005622=GO_REF:0000002, GO:0007165=PMID:7512734, GO:0016337=GO_REF:0000019, GO:0000186=Reactome:REACT_12005, GO:0048008=GO_REF:0000019, GO:0007169=PMID:7512734, GO:0005768=Reactome:REACT_12015} Q5JUE6 Rap guanine nucleotide exchange factor 1 protein 20130413 {GO:0005515=IPI, GO:0051056=IEA, GO:0048011=TAS, GO:0017124=IEA, GO:0001568=IEA, GO:0007264=IEA, GO:0005829=TAS, GO:0005085=IEA, GO:0005622=IEA, GO:0007165=NAS, GO:0016337=IEA, GO:0000186=TAS, GO:0048008=IEA, GO:0007169=TAS, GO:0005768=TAS} activation of MAPKK activity, blood vessel development, cell-cell adhesion, neurotrophin TRK receptor signaling pathway, platelet-derived growth factor receptor signaling pathway, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction, transmembrane receptor protein tyrosine kinase signaling pathway cytosol, endosome, intracellular SH3 domain binding, guanyl-nucleotide exchange factor activity, protein binding Human UniProtKB-KW:KW-0344 RAPGEF2 UniProtKB UniProtKB {GO:0019901=GO_REF:0000019, GO:0007264=PMID:10934204, GO:0005509=PMID:10934204, GO:0032854=GO_REF:0000019, GO:0019992=PMID:10934204, GO:0035556=PMID:10608883, GO:0005085=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0046582=PMID:10934204, GO:0016020=PMID:10608883, GO:0048167=GO_REF:0000024, GO:0000165=PMID:10934204, GO:0005887=PMID:10934204, GO:0019933=PMID:10934204, GO:0004871=PMID:10934204, GO:0017034=PMID:10608883} Q9Y4G8 Rap guanine nucleotide exchange factor 2 protein 20111110 {GO:0019901=IEA, GO:0007264=TAS, GO:0005509=NAS, GO:0032854=IEA, GO:0019992=NAS, GO:0035556=TAS, GO:0005085=IEA, GO:0005622=IEA, GO:0046582=IDA, GO:0016020=IDA, GO:0048167=ISS, GO:0000165=NAS, GO:0005887=NAS, GO:0019933=NAS, GO:0004871=TAS, GO:0017034=IDA} MAPK cascade, cAMP-mediated signaling, intracellular signal transduction, positive regulation of Rap GTPase activity, regulation of synaptic plasticity, small GTPase mediated signal transduction integral to plasma membrane, intracellular, membrane Rap GTPase activator activity, Rap guanyl-nucleotide exchange factor activity, calcium ion binding, diacylglycerol binding, guanyl-nucleotide exchange factor activity, protein kinase binding, signal transducer activity Human UniProtKB:F1M386 RAPGEF3 IntAct UniProtKB {GO:0005515=PMID:21393242, GO:0051056=GO_REF:0000002, GO:0005952=GO_REF:0000002, GO:0005886=Reactome:REACT_23933, GO:0008603=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0008283=PMID:9853756, GO:0030168=Reactome:REACT_798, GO:0044281=Reactome:REACT_111217, GO:0001525=GO_REF:0000037, GO:0045766=PMID:21393242, GO:0012505=GO_REF:0000039, GO:0005085=GO_REF:0000019, GO:0005622=GO_REF:0000002, GO:0007165=PMID:9853756, GO:0006112=Reactome:REACT_1505, GO:0030552=GO_REF:0000037, GO:0050796=Reactome:REACT_18325, GO:0016020=PMID:10777494, GO:0007596=Reactome:REACT_604} O95398 Rap guanine nucleotide exchange factor 3 protein 20130415 {GO:0005515=IPI, GO:0051056=IEA, GO:0005952=IEA, GO:0005886=TAS, GO:0008603=IEA, GO:0007264=IEA, GO:0008283=TAS, GO:0030168=TAS, GO:0044281=TAS, GO:0001525=IEA, GO:0045766=IMP, GO:0012505=IEA, GO:0005085=IEA, GO:0005622=IEA, GO:0007165=TAS, GO:0006112=TAS, GO:0030552=IEA, GO:0050796=TAS, GO:0016020=TAS, GO:0007596=TAS} angiogenesis, blood coagulation, cell proliferation, energy reserve metabolic process, platelet activation, positive regulation of angiogenesis, regulation of insulin secretion, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction, small molecule metabolic process cAMP-dependent protein kinase complex, endomembrane system, intracellular, membrane, plasma membrane cAMP binding, cAMP-dependent protein kinase regulator activity, guanyl-nucleotide exchange factor activity, protein binding Human UniProtKB:Q13370 RAPGEF4 Reactome UniProtKB {GO:0005515=PMID:11438518, GO:0051056=GO_REF:0000002, GO:0005952=GO_REF:0000002, GO:0005886=Reactome:REACT_23933, GO:0008603=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0030168=Reactome:REACT_798, GO:0044281=Reactome:REACT_111217, GO:0005829=GO_REF:0000019, GO:0005622=GO_REF:0000002, GO:0005085=PMID:9856955, GO:0006112=Reactome:REACT_1505, GO:0030552=GO_REF:0000024, GO:0050796=Reactome:REACT_18325, GO:0016020=PMID:10777494, GO:0007186=PMID:9856955, GO:0007596=Reactome:REACT_604, GO:0017156=GO_REF:0000019, GO:0017157=GO_REF:0000019, GO:0019933=GO_REF:0000019, GO:0017016=GO_REF:0000024, GO:0030073=GO_REF:0000019, GO:0005088=GO_REF:0000024} Q8WZA2 Rap guanine nucleotide exchange factor 4 protein 20130201 {GO:0005515=IPI, GO:0051056=IEA, GO:0005952=IEA, GO:0005886=TAS, GO:0008603=IEA, GO:0007264=IEA, GO:0030168=TAS, GO:0044281=TAS, GO:0005829=IEA, GO:0005622=IEA, GO:0005085=TAS, GO:0006112=TAS, GO:0030552=ISS, GO:0050796=TAS, GO:0016020=TAS, GO:0007186=TAS, GO:0007596=TAS, GO:0017156=IEA, GO:0017157=IEA, GO:0019933=IEA, GO:0017016=ISS, GO:0030073=IEA, GO:0005088=ISS} G-protein coupled receptor signaling pathway, blood coagulation, cAMP-mediated signaling, calcium ion-dependent exocytosis, energy reserve metabolic process, insulin secretion, platelet activation, regulation of exocytosis, regulation of insulin secretion, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction, small molecule metabolic process cAMP-dependent protein kinase complex, cytosol, intracellular, membrane, plasma membrane Ras GTPase binding, Ras guanyl-nucleotide exchange factor activity, cAMP binding, cAMP-dependent protein kinase regulator activity, guanyl-nucleotide exchange factor activity, protein binding Human RAPGEF5 UniProtKB UniProtKB {GO:0035556=GO_REF:0000002, GO:0005085=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0051056=GO_REF:0000002, GO:0030742=PMID:10934204, GO:0007264=PMID:10486569, GO:0005634=PMID:10486569, GO:0017034=PMID:10486569, GO:0005088=PMID:10934204, GO:0007399=PMID:10486569} Q92565 Rap guanine nucleotide exchange factor 5 protein 20030813 {GO:0035556=IEA, GO:0005085=IEA, GO:0005622=IEA, GO:0051056=IEA, GO:0030742=IPI, GO:0007264=NAS, GO:0005634=IDA, GO:0017034=IDA, GO:0005088=TAS, GO:0007399=NAS} intracellular signal transduction, nervous system development, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction intracellular, nucleus GTP-dependent protein binding, Rap guanyl-nucleotide exchange factor activity, Ras guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity Human UniProtKB:O14807 RAPGEF6 UniProtKB UniProtKB {GO:0005085=PMID:11524421, GO:0005622=GO_REF:0000002, GO:0051056=GO_REF:0000002, GO:0030742=PMID:11524421, GO:0005737=GO_REF:0000039, GO:0005886=PMID:11524421, GO:0007264=GO_REF:0000002, GO:0007265=PMID:11524421, GO:0017016=PMID:11524421, GO:0043087=PMID:11524421} Q8TEU7 Rap guanine nucleotide exchange factor 6 protein 20040430 {GO:0005085=IDA, GO:0005622=IEA, GO:0051056=IEA, GO:0030742=IDA, GO:0005737=IEA, GO:0005886=IDA, GO:0007264=IEA, GO:0007265=NAS, GO:0017016=IDA, GO:0043087=NAS} Ras protein signal transduction, regulation of GTPase activity, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytoplasm, intracellular, plasma membrane GTP-dependent protein binding, Ras GTPase binding, guanyl-nucleotide exchange factor activity Human RAPGEFL1 PINC UniProtKB {GO:0005622=GO_REF:0000002, GO:0005085=GO_REF:0000037, GO:0007186=PMID:9582122, GO:0016020=PMID:9582122, GO:0007264=GO_REF:0000002, GO:0005057=GO_REF:0000002, GO:0007399=PMID:9789079} Q9UHV5 Rap guanine nucleotide exchange factor-like 1 protein 20030904 {GO:0005622=IEA, GO:0005085=IEA, GO:0007186=TAS, GO:0016020=TAS, GO:0007264=IEA, GO:0005057=IEA, GO:0007399=TAS} G-protein coupled receptor signaling pathway, nervous system development, small GTPase mediated signal transduction intracellular, membrane guanyl-nucleotide exchange factor activity, receptor signaling protein activity Human RAPH1 UniProtKB UniProtKB {GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000037, GO:0005543=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0007160=GO_REF:0000002, GO:0048675=GO_REF:0000019, GO:0030175=GO_REF:0000039, GO:0005856=GO_REF:0000039, GO:0031252=GO_REF:0000019, GO:0030027=GO_REF:0000039} Q70E73 Ras-associated and pleckstrin homology domains-containing protein 1 protein 20130413 {GO:0007165=IEA, GO:0005737=IEA, GO:0005543=IEA, GO:0005886=IEA, GO:0007160=IEA, GO:0048675=IEA, GO:0030175=IEA, GO:0005856=IEA, GO:0031252=IEA, GO:0030027=IEA} axon extension, cell-matrix adhesion, signal transduction cell leading edge, cytoplasm, cytoskeleton, filopodium, lamellipodium, plasma membrane phospholipid binding Human UniProtKB-SubCell:SL-0286 RAPSN HPA UniProtKB {GO:0030054=GO_REF:0000037, GO:0005794=GO_REF:0000019, GO:0031594=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0007268=PMID:8812503, GO:0033130=PMID:18420419, GO:0007271=PMID:18420419, GO:0005737=GO_REF:0000052, GO:0043525=GO_REF:0000019, GO:0035255=GO_REF:0000019, GO:0045211=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0005856=GO_REF:0000039} Q13702 43 kDa receptor-associated protein of the synapse protein 20111111 {GO:0030054=IEA, GO:0005794=IEA, GO:0031594=IEA, GO:0005886=IDA, GO:0007268=TAS, GO:0033130=IDA, GO:0007271=IGI, GO:0005737=IDA, GO:0043525=IEA, GO:0035255=IEA, GO:0045211=IEA, GO:0008270=IEA, GO:0005856=IEA} positive regulation of neuron apoptotic process, synaptic transmission, synaptic transmission, cholinergic Golgi apparatus, cell junction, cytoplasm, cytoskeleton, neuromuscular junction, plasma membrane, postsynaptic membrane acetylcholine receptor binding, ionotropic glutamate receptor binding, zinc ion binding Human RARA BHF-UCL UniProtKB {GO:0005515=PMID:17363140, GO:0010467=Reactome:REACT_71, GO:0001657=GO_REF:0000019, GO:0032753=PMID:18416830, GO:0000790=PMID:17363140, GO:0003417=GO_REF:0000019, GO:0032754=PMID:18416830, GO:0006367=Reactome:REACT_15525, GO:0003700=PMID:18922886, GO:0044212=GO_REF:0000019, GO:0071300=PMID:19917671, GO:0055012=GO_REF:0000019, GO:0003707=GO_REF:0000002, GO:0003708=PMID:2825025, GO:0007283=GO_REF:0000019, GO:0007281=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0070374=GO_REF:0000019, GO:0004879=GO_REF:0000019, GO:0051018=PMID:20215566, GO:0032689=PMID:18416830, GO:0032355=PMID:15831516, GO:0009986=PMID:2825025, GO:0046982=PMID:19917671, GO:0003714=PMID:20080953, GO:0019904=PMID:20413580, GO:0003713=PMID:2825025, GO:0032720=PMID:18416830, GO:0044323=PMID:19917671, GO:0043277=PMID:19628791, GO:0014068=GO_REF:0000019, GO:0071391=PMID:20080953, GO:0000122=GO_REF:0000019, GO:0045787=PMID:20080953, GO:0031490=PMID:19917671, GO:0048384=PMID:17538076, GO:0005654=Reactome:REACT_19207, GO:0008270=GO_REF:0000002, GO:0045596=GO_REF:0000019, GO:0019899=PMID:12039952, GO:0045893=PMID:18845237, GO:0045892=PMID:20080953, GO:0008134=PMID:17641689, GO:0051897=GO_REF:0000019, GO:0008284=PMID:20080953, GO:0060591=GO_REF:0000019, GO:0005634=PMID:18845237, GO:0032736=PMID:18416830, GO:0030425=GO_REF:0000019, GO:0005737=PMID:19850744, GO:0035264=GO_REF:0000019, GO:0045944=PMID:19850744, GO:0030852=GO_REF:0000019, GO:0030853=PMID:19917671, GO:0045947=GO_REF:0000019, GO:0032526=PMID:17538076, GO:0045630=PMID:18416830, GO:0035014=GO_REF:0000019, GO:0005102=PMID:19628791, GO:0051099=PMID:20080953, GO:0043422=PMID:16417524, GO:0043565=GO_REF:0000002, GO:0010628=GO_REF:0000019, GO:0007165=PMID:2825025, GO:0071222=GO_REF:0000019, GO:0001972=PMID:2825025, GO:0061037=GO_REF:0000019, GO:0006468=PMID:16456540, GO:0060010=GO_REF:0000019, GO:0030520=PMID:15831516} P10276 Retinoic acid receptor alpha protein 20080624 {GO:0005515=IPI, GO:0010467=TAS, GO:0001657=IEA, GO:0032753=IDA, GO:0000790=IDA, GO:0003417=IEA, GO:0032754=IDA, GO:0006367=TAS, GO:0003700=IDA, GO:0044212=IEA, GO:0071300=IDA, GO:0055012=IEA, GO:0003707=IEA, GO:0003708=IDA, GO:0007283=IEA, GO:0007281=IEA, GO:0043025=IEA, GO:0070374=IEA, GO:0004879=IEA, GO:0051018=IDA, GO:0032689=IDA, GO:0032355=IDA, GO:0009986=IC, GO:0046982=IDA, GO:0003714=IDA, GO:0019904=IPI, GO:0003713=IDA, GO:0032720=IDA, GO:0044323=IDA, GO:0043277=IMP, GO:0014068=IEA, GO:0071391=IDA, GO:0000122=IEA, GO:0045787=IMP, GO:0031490=IDA, GO:0048384=IMP, GO:0005654=TAS, GO:0008270=IEA, GO:0045596=IEA, GO:0019899=IPI, GO:0045893=IDA, GO:0045892=IDA, GO:0008134=IPI, GO:0051897=IEA, GO:0008284=IMP, GO:0060591=IEA, GO:0005634=IDA, GO:0032736=IDA, GO:0030425=IEA, GO:0005737=IDA, GO:0035264=IEA, GO:0045944=IDA, GO:0030852=IEA, GO:0030853=IDA, GO:0045947=IEA, GO:0032526=IMP, GO:0045630=IDA, GO:0035014=IEA, GO:0005102=IDA, GO:0051099=IMP, GO:0043422=IPI, GO:0043565=IEA, GO:0010628=IEA, GO:0007165=IDA, GO:0071222=IEA, GO:0001972=IDA, GO:0061037=IEA, GO:0006468=IMP, GO:0060010=IEA, GO:0030520=IDA} Sertoli cell fate commitment, apoptotic cell clearance, cellular response to estrogen stimulus, cellular response to lipopolysaccharide, cellular response to retinoic acid, chondroblast differentiation, gene expression, germ cell development, growth plate cartilage development, intracellular estrogen receptor signaling pathway, multicellular organism growth, negative regulation of cartilage development, negative regulation of cell differentiation, negative regulation of granulocyte differentiation, negative regulation of interferon-gamma production, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, negative regulation of translational initiation, negative regulation of tumor necrosis factor production, positive regulation of ERK1 and ERK2 cascade, positive regulation of T-helper 2 cell differentiation, positive regulation of binding, positive regulation of cell cycle, positive regulation of cell proliferation, positive regulation of gene expression, positive regulation of interleukin-13 production, positive regulation of interleukin-4 production, positive regulation of interleukin-5 production, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of protein kinase B signaling cascade, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein phosphorylation, regulation of granulocyte differentiation, response to estradiol stimulus, response to retinoic acid, retinoic acid receptor signaling pathway, signal transduction, spermatogenesis, transcription initiation from RNA polymerase II promoter, ureteric bud development, ventricular cardiac muscle cell differentiation cell surface, cytoplasm, dendrite, neuronal cell body, nuclear chromatin, nucleoplasm, nucleus chromatin DNA binding, enzyme binding, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, phosphatidylinositol 3-kinase regulator activity, protein binding, protein domain specific binding, protein heterodimerization activity, protein kinase A binding, protein kinase B binding, receptor binding, retinoic acid binding, retinoic acid receptor activity, retinoic acid-responsive element binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity, transcription coactivator activity, transcription corepressor activity, transcription factor binding, transcription regulatory region DNA binding, zinc ion binding Human RARB Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0001657=GO_REF:0000019, GO:0003417=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0006367=Reactome:REACT_15525, GO:0055012=GO_REF:0000019, GO:0003707=GO_REF:0000002, GO:0005634=PMID:18845237, GO:0003708=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0035264=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0032331=GO_REF:0000019, GO:0022008=GO_REF:0000019, GO:0048048=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0048566=PMID:19443732, GO:0003677=PMID:2153268, GO:0043565=GO_REF:0000019, GO:0021756=GO_REF:0000019, GO:0007165=PMID:2833708, GO:0035116=GO_REF:0000019, GO:0061037=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_19207} P10826 Retinoic acid receptor beta protein 20130301 {GO:0010467=TAS, GO:0001657=IEA, GO:0003417=IEA, GO:0008285=IEA, GO:0006367=TAS, GO:0055012=IEA, GO:0003707=IEA, GO:0005634=IDA, GO:0003708=IEA, GO:0005737=IEA, GO:0035264=IEA, GO:0045944=IEA, GO:0032331=IEA, GO:0022008=IEA, GO:0048048=IEA, GO:0043065=IEA, GO:0000122=IEA, GO:0048566=IMP, GO:0003677=TAS, GO:0043565=IEA, GO:0021756=IEA, GO:0007165=TAS, GO:0035116=IEA, GO:0061037=IEA, GO:0008270=IEA, GO:0005654=TAS} embryonic digestive tract development, embryonic eye morphogenesis, embryonic hindlimb morphogenesis, gene expression, growth plate cartilage development, multicellular organism growth, negative regulation of cartilage development, negative regulation of cell proliferation, negative regulation of chondrocyte differentiation, negative regulation of transcription from RNA polymerase II promoter, neurogenesis, positive regulation of apoptotic process, positive regulation of transcription from RNA polymerase II promoter, signal transduction, striatum development, transcription initiation from RNA polymerase II promoter, ureteric bud development, ventricular cardiac muscle cell differentiation cytoplasm, nucleoplasm, nucleus DNA binding, retinoic acid receptor activity, sequence-specific DNA binding, steroid hormone receptor activity, zinc ion binding Human RARG BHF-UCL UniProtKB {GO:0005515=PMID:16456540, GO:0008361=PMID:18438858, GO:0010467=Reactome:REACT_71, GO:0008284=GO_REF:0000019, GO:0003700=GO_REF:0000024, GO:0006367=Reactome:REACT_15525, GO:0008285=GO_REF:0000024, GO:0003430=GO_REF:0000019, GO:0071300=GO_REF:0000019, GO:0003707=GO_REF:0000002, GO:0005634=GO_REF:0000024, GO:0003708=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0046965=GO_REF:0000024, GO:0043068=GO_REF:0000024, GO:0035264=GO_REF:0000019, GO:0045944=GO_REF:0000024, GO:0031641=GO_REF:0000019, GO:0032526=PMID:17943189, GO:0032331=GO_REF:0000019, GO:0060070=PMID:18484682, GO:0048048=GO_REF:0000024, GO:0005667=GO_REF:0000024, GO:0043065=GO_REF:0000024, GO:0060740=GO_REF:0000019, GO:0000122=GO_REF:0000024, GO:0003677=GO_REF:0000024, GO:0048384=PMID:17943189, GO:0043565=GO_REF:0000002, GO:0035116=GO_REF:0000024, GO:0070384=GO_REF:0000019, GO:0061037=GO_REF:0000019, GO:0005654=Reactome:REACT_19207, GO:0008270=GO_REF:0000002, GO:0016021=PMID:17943189, GO:0060534=GO_REF:0000019} P13631 Retinoic acid receptor gamma protein 20080625 {GO:0005515=IPI, GO:0008361=TAS, GO:0010467=TAS, GO:0008284=IEA, GO:0003700=ISS, GO:0006367=TAS, GO:0008285=ISS, GO:0003430=IEA, GO:0071300=IEA, GO:0003707=IEA, GO:0005634=ISS, GO:0003708=IEA, GO:0009952=IEA, GO:0046965=ISS, GO:0043068=ISS, GO:0035264=IEA, GO:0045944=ISS, GO:0031641=IEA, GO:0032526=IDA, GO:0032331=IEA, GO:0060070=TAS, GO:0048048=ISS, GO:0005667=ISS, GO:0043065=ISS, GO:0060740=IEA, GO:0000122=ISS, GO:0003677=ISS, GO:0048384=IDA, GO:0043565=IEA, GO:0035116=ISS, GO:0070384=IEA, GO:0061037=IEA, GO:0005654=TAS, GO:0008270=IEA, GO:0016021=NAS, GO:0060534=IEA} Harderian gland development, anterior/posterior pattern specification, canonical Wnt receptor signaling pathway, cellular response to retinoic acid, embryonic eye morphogenesis, embryonic hindlimb morphogenesis, gene expression, growth plate cartilage chondrocyte growth, multicellular organism growth, negative regulation of cartilage development, negative regulation of cell proliferation, negative regulation of chondrocyte differentiation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of apoptotic process, positive regulation of cell proliferation, positive regulation of programmed cell death, positive regulation of transcription from RNA polymerase II promoter, prostate gland epithelium morphogenesis, regulation of cell size, regulation of myelination, response to retinoic acid, retinoic acid receptor signaling pathway, trachea cartilage development, transcription initiation from RNA polymerase II promoter integral to membrane, nucleoplasm, nucleus, transcription factor complex DNA binding, protein binding, retinoic acid receptor activity, retinoid X receptor binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity, zinc ion binding Human UniProtKB:P18911 RARRES3 PINC UniProtKB {GO:0016042=GO_REF:0000037, GO:0008285=PMID:9843971, GO:0004623=PMID:20100577, GO:0016021=GO_REF:0000037, GO:0006644=PMID:20100577} Q9UL19 Retinoic acid receptor responder protein 3 protein 20050308 {GO:0016042=IEA, GO:0008285=TAS, GO:0004623=IDA, GO:0016021=IEA, GO:0006644=IDA} lipid catabolic process, negative regulation of cell proliferation, phospholipid metabolic process integral to membrane phospholipase A2 activity Human RARS HPA UniProtKB {GO:0005515=PMID:16055448, GO:0010467=Reactome:REACT_71, GO:0000049=GO_REF:0000019, GO:0004814=Reactome:REACT_15489, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000019, GO:0017101=GO_REF:0000019, GO:0005829=Reactome:REACT_15516, GO:0006418=Reactome:REACT_15482, GO:0005739=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0034618=GO_REF:0000019, GO:0006420=GO_REF:0000019} P54136 Arginine--tRNA ligase, cytoplasmic protein 20101115 {GO:0005515=IPI, GO:0010467=TAS, GO:0000049=IEA, GO:0004814=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0005524=IEA, GO:0017101=IEA, GO:0005829=TAS, GO:0006418=TAS, GO:0005739=IEA, GO:0005737=IDA, GO:0034618=IEA, GO:0006420=IEA} arginyl-tRNA aminoacylation, gene expression, tRNA aminoacylation for protein translation aminoacyl-tRNA synthetase multienzyme complex, cytoplasm, cytosol, mitochondrion, nucleolus, nucleus ATP binding, arginine binding, arginine-tRNA ligase activity, protein binding, tRNA binding Human RARS2 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0005737=GO_REF:0000002, GO:0005759=Reactome:REACT_15544, GO:0006420=GO_REF:0000002, GO:0004814=GO_REF:0000003, GO:0005524=GO_REF:0000037, GO:0006418=Reactome:REACT_15482} Q5T160 Probable arginine--tRNA ligase, mitochondrial protein 20130301 {GO:0010467=TAS, GO:0005737=IEA, GO:0005759=TAS, GO:0006420=IEA, GO:0004814=IEA, GO:0005524=IEA, GO:0006418=TAS} arginyl-tRNA aminoacylation, gene expression, tRNA aminoacylation for protein translation cytoplasm, mitochondrial matrix ATP binding, arginine-tRNA ligase activity Human RASA1 IntAct UniProtKB {GO:0005515=PMID:21664272, GO:0051252=PMID:9113414, GO:0008360=PMID:9113414, GO:0009790=GO_REF:0000024, GO:0005829=Reactome:REACT_16950, GO:0005622=GO_REF:0000002, GO:0035556=PMID:1581965, GO:0000910=GO_REF:0000024, GO:0046580=GO_REF:0000033, GO:0005737=PMID:2821624, GO:0043524=GO_REF:0000024, GO:0001948=PMID:8618896, GO:0005543=GO_REF:0000002, GO:0030833=PMID:8344248, GO:0051056=GO_REF:0000002, GO:0031235=GO_REF:0000033, GO:0005102=PMID:2157284, GO:0001726=GO_REF:0000019, GO:0005099=GO_REF:0000033, GO:0007165=PMID:1756860, GO:0007162=PMID:8344248, GO:0051020=PMID:2122974, GO:0032320=GO_REF:0000033, GO:0019870=PMID:1553544, GO:0001570=GO_REF:0000024, GO:0005096=GO_REF:0000038, GO:0001953=PMID:8344248} P20936 Ras GTPase-activating protein 1 protein 20130415 {GO:0005515=IPI, GO:0051252=NAS, GO:0008360=NAS, GO:0009790=ISS, GO:0005829=TAS, GO:0005622=IEA, GO:0035556=NAS, GO:0000910=ISS, GO:0046580=IBA, GO:0005737=NAS, GO:0043524=ISS, GO:0001948=IPI, GO:0005543=IEA, GO:0030833=IDA, GO:0051056=IEA, GO:0031235=IBA, GO:0005102=IPI, GO:0001726=IEA, GO:0005099=IBA, GO:0007165=IDA, GO:0007162=IDA, GO:0051020=IPI, GO:0032320=IBA, GO:0019870=NAS, GO:0001570=ISS, GO:0005096=IEA, GO:0001953=IDA} cytokinesis, embryo development, intracellular signal transduction, negative regulation of Ras protein signal transduction, negative regulation of cell adhesion, negative regulation of cell-matrix adhesion, negative regulation of neuron apoptotic process, positive regulation of Ras GTPase activity, regulation of RNA metabolic process, regulation of actin filament polymerization, regulation of cell shape, regulation of small GTPase mediated signal transduction, signal transduction, vasculogenesis cytoplasm, cytosol, intracellular, intrinsic to internal side of plasma membrane, ruffle GTPase activator activity, GTPase binding, Ras GTPase activator activity, glycoprotein binding, phospholipid binding, potassium channel inhibitor activity, protein binding, receptor binding Human UniProtKB:P16333 RASA2 HPA UniProtKB {GO:0051056=GO_REF:0000002, GO:0048471=GO_REF:0000039, GO:0031235=GO_REF:0000033, GO:0046872=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0035556=GO_REF:0000002, GO:0005099=GO_REF:0000033, GO:0046580=GO_REF:0000033, GO:0007165=PMID:8812506, GO:0005737=GO_REF:0000033, GO:0005543=GO_REF:0000002, GO:0032320=GO_REF:0000033, GO:0005096=GO_REF:0000038} Q15283 Ras GTPase-activating protein 2 protein 20101115 {GO:0051056=IEA, GO:0048471=IEA, GO:0031235=IBA, GO:0046872=IEA, GO:0043231=IDA, GO:0035556=IEA, GO:0005099=IBA, GO:0046580=IBA, GO:0007165=TAS, GO:0005737=IBA, GO:0005543=IEA, GO:0032320=IBA, GO:0005096=IEA} intracellular signal transduction, negative regulation of Ras protein signal transduction, positive regulation of Ras GTPase activity, regulation of small GTPase mediated signal transduction, signal transduction cytoplasm, intracellular membrane-bounded organelle, intrinsic to internal side of plasma membrane, perinuclear region of cytoplasm GTPase activator activity, Ras GTPase activator activity, metal ion binding, phospholipid binding Human RASA3 BHF-UCL UniProtKB {GO:0051056=GO_REF:0000002, GO:0031235=PMID:10828023, GO:0046872=GO_REF:0000037, GO:0005622=GO_REF:0000002, GO:0035556=GO_REF:0000002, GO:0005099=GO_REF:0000033, GO:0046580=GO_REF:0000033, GO:0007165=PMID:7637787, GO:0005737=GO_REF:0000033, GO:0005543=GO_REF:0000002, GO:0032320=GO_REF:0000033, GO:0015278=PMID:10828023, GO:0005096=PMID:7637787} Q14644 Ras GTPase-activating protein 3 protein 20090520 {GO:0051056=IEA, GO:0031235=IDA, GO:0046872=IEA, GO:0005622=IEA, GO:0035556=IEA, GO:0005099=IBA, GO:0046580=IBA, GO:0007165=TAS, GO:0005737=IBA, GO:0005543=IEA, GO:0032320=IBA, GO:0015278=IDA, GO:0005096=TAS} intracellular signal transduction, negative regulation of Ras protein signal transduction, positive regulation of Ras GTPase activity, regulation of small GTPase mediated signal transduction, signal transduction cytoplasm, intracellular, intrinsic to internal side of plasma membrane GTPase activator activity, Ras GTPase activator activity, calcium-release channel activity, metal ion binding, phospholipid binding Human RASA4 UniProtKB UniProtKB {GO:0051056=GO_REF:0000002, GO:0031235=GO_REF:0000033, GO:0046872=GO_REF:0000037, GO:0005829=GO_REF:0000039, GO:0005622=GO_REF:0000002, GO:0035556=GO_REF:0000002, GO:0005099=GO_REF:0000033, GO:0007165=GO_REF:0000002, GO:0046580=GO_REF:0000033, GO:0005737=GO_REF:0000033, GO:0005543=GO_REF:0000002, GO:0032320=GO_REF:0000033, GO:0005096=PMID:11448776} O43374 Ras GTPase-activating protein 4 protein 20041105 {GO:0051056=IEA, GO:0031235=IBA, GO:0046872=IEA, GO:0005829=IEA, GO:0005622=IEA, GO:0035556=IEA, GO:0005099=IBA, GO:0007165=IEA, GO:0046580=IBA, GO:0005737=IBA, GO:0005543=IEA, GO:0032320=IBA, GO:0005096=IDA} intracellular signal transduction, negative regulation of Ras protein signal transduction, positive regulation of Ras GTPase activity, regulation of small GTPase mediated signal transduction, signal transduction cytoplasm, cytosol, intracellular, intrinsic to internal side of plasma membrane GTPase activator activity, Ras GTPase activator activity, metal ion binding, phospholipid binding Human RASA4B UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0035556=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0051056=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0046872=GO_REF:0000037, GO:0005829=GO_REF:0000039, GO:0005096=GO_REF:0000038} J3KR53 Putative Ras GTPase-activating protein 4B protein 20130413 {GO:0005622=IEA, GO:0035556=IEA, GO:0007165=IEA, GO:0051056=IEA, GO:0005543=IEA, GO:0005886=IEA, GO:0046872=IEA, GO:0005829=IEA, GO:0005096=IEA} intracellular signal transduction, regulation of small GTPase mediated signal transduction, signal transduction cytosol, intracellular, plasma membrane GTPase activator activity, metal ion binding, phospholipid binding Human UniProtKB-KW:KW-0343 RASAL1 PINC UniProtKB {GO:0005099=GO_REF:0000033, GO:0035556=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0007165=PMID:9751798, GO:0046580=GO_REF:0000033, GO:0051056=GO_REF:0000002, GO:0005737=GO_REF:0000033, GO:0005543=GO_REF:0000002, GO:0032320=GO_REF:0000033, GO:0031235=GO_REF:0000033, GO:0046872=GO_REF:0000037, GO:0005096=GO_REF:0000038} O95294 RasGAP-activating-like protein 1 protein 20030904 {GO:0005099=IBA, GO:0035556=IEA, GO:0005622=IEA, GO:0007165=TAS, GO:0046580=IBA, GO:0051056=IEA, GO:0005737=IBA, GO:0005543=IEA, GO:0032320=IBA, GO:0031235=IBA, GO:0046872=IEA, GO:0005096=IEA} intracellular signal transduction, negative regulation of Ras protein signal transduction, positive regulation of Ras GTPase activity, regulation of small GTPase mediated signal transduction, signal transduction cytoplasm, intracellular, intrinsic to internal side of plasma membrane GTPase activator activity, Ras GTPase activator activity, metal ion binding, phospholipid binding Human RASAL2 RefGenome UniProtKB {GO:0005099=GO_REF:0000033, GO:0005622=GO_REF:0000002, GO:0046580=GO_REF:0000033, GO:0051056=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000033, GO:0005543=GO_REF:0000002, GO:0032320=GO_REF:0000033, GO:0031235=GO_REF:0000033, GO:0005096=GO_REF:0000002} Q9UJF2 Ras GTPase-activating protein nGAP protein 20110114 {GO:0005099=IBA, GO:0005622=IEA, GO:0046580=IBA, GO:0051056=IEA, GO:0007165=IEA, GO:0005737=IBA, GO:0005543=IEA, GO:0032320=IBA, GO:0031235=IBA, GO:0005096=IEA} negative regulation of Ras protein signal transduction, positive regulation of Ras GTPase activity, regulation of small GTPase mediated signal transduction, signal transduction cytoplasm, intracellular, intrinsic to internal side of plasma membrane GTPase activator activity, Ras GTPase activator activity, phospholipid binding Human PANTHER:PTN000022879 RASAL3 RefGenome UniProtKB {GO:0005099=GO_REF:0000033, GO:0005622=GO_REF:0000002, GO:0046580=GO_REF:0000033, GO:0051056=GO_REF:0000002, GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000033, GO:0005543=GO_REF:0000002, GO:0032320=GO_REF:0000033, GO:0031235=GO_REF:0000033, GO:0005096=GO_REF:0000002} Q86YV0 RAS protein activator like-3 protein 20110114 {GO:0005099=IBA, GO:0005622=IEA, GO:0046580=IBA, GO:0051056=IEA, GO:0007165=IEA, GO:0005737=IBA, GO:0005543=IEA, GO:0032320=IBA, GO:0031235=IBA, GO:0005096=IEA} negative regulation of Ras protein signal transduction, positive regulation of Ras GTPase activity, regulation of small GTPase mediated signal transduction, signal transduction cytoplasm, intracellular, intrinsic to internal side of plasma membrane GTPase activator activity, Ras GTPase activator activity, phospholipid binding Human PANTHER:PTN000022879 RASD1 PINC UniProtKB {GO:0007165=PMID:10673050, GO:0048471=GO_REF:0000039, GO:0007186=PMID:10840027, GO:0005886=GO_REF:0000039, GO:0007263=GO_REF:0000019, GO:0007264=GO_REF:0000002, GO:0003924=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0005525=GO_REF:0000037, GO:0045892=GO_REF:0000019} Q9Y272 Dexamethasone-induced Ras-related protein 1 protein 20030904 {GO:0007165=TAS, GO:0048471=IEA, GO:0007186=TAS, GO:0005886=IEA, GO:0007263=IEA, GO:0007264=IEA, GO:0003924=IEA, GO:0005634=IEA, GO:0005525=IEA, GO:0045892=IEA} G-protein coupled receptor signaling pathway, negative regulation of transcription, DNA-dependent, nitric oxide mediated signal transduction, signal transduction, small GTPase mediated signal transduction nucleus, perinuclear region of cytoplasm, plasma membrane GTP binding, GTPase activity Human RASD2 UniProtKB UniProtKB {GO:0051897=GO_REF:0000024, GO:0031681=PMID:19255495, GO:0005886=GO_REF:0000024, GO:0007264=PMID:11976265, GO:0003924=PMID:11976265, GO:0005525=GO_REF:0000019, GO:0043949=GO_REF:0000024, GO:0001963=GO_REF:0000019, GO:0033235=GO_REF:0000024, GO:0007626=GO_REF:0000024, GO:0031397=GO_REF:0000019, GO:0031624=GO_REF:0000019, GO:0043548=GO_REF:0000019} Q96D21 GTP-binding protein Rhes protein 20110616 {GO:0051897=ISS, GO:0031681=IPI, GO:0005886=ISS, GO:0007264=IC, GO:0003924=NAS, GO:0005525=IEA, GO:0043949=ISS, GO:0001963=IEA, GO:0033235=ISS, GO:0007626=ISS, GO:0031397=IEA, GO:0031624=IEA, GO:0043548=IEA} locomotory behavior, negative regulation of protein ubiquitination, positive regulation of protein kinase B signaling cascade, positive regulation of protein sumoylation, regulation of cAMP-mediated signaling, small GTPase mediated signal transduction, synaptic transmission, dopaminergic plasma membrane G-protein beta-subunit binding, GTP binding, GTPase activity, phosphatidylinositol 3-kinase binding, ubiquitin conjugating enzyme binding Human UniProtKB:P16520 RASEF UniProtKB UniProtKB {GO:0048471=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0015031=GO_REF:0000002} Q8IZ41 Ras and EF-hand domain-containing protein protein 20130413 {GO:0048471=IEA, GO:0007264=IEA, GO:0005509=IEA, GO:0005525=IEA, GO:0015031=IEA} protein transport, small GTPase mediated signal transduction perinuclear region of cytoplasm GTP binding, calcium ion binding Human UniProtKB-SubCell:SL-0198 RASGEF1A UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0005085=GO_REF:0000002, GO:0051056=GO_REF:0000002, GO:0016477=PMID:17121879, GO:0007264=GO_REF:0000002, GO:0005088=PMID:17121879} Q8N9B8 Ras-GEF domain-containing family member 1A protein 20100907 {GO:0005622=IEA, GO:0005085=IEA, GO:0051056=IEA, GO:0016477=IDA, GO:0007264=IEA, GO:0005088=IDA} cell migration, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction intracellular Ras guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity Human RASGEF1C UniProtKB UniProtKB {GO:0005085=GO_REF:0000037, GO:0005622=GO_REF:0000002, GO:0051056=GO_REF:0000002, GO:0007264=GO_REF:0000002} Q8N431 Ras-GEF domain-containing family member 1C protein 20130413 {GO:0005085=IEA, GO:0005622=IEA, GO:0051056=IEA, GO:0007264=IEA} regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction intracellular guanyl-nucleotide exchange factor activity Human UniProtKB-KW:KW-0344 RASGRF1 Reactome UniProtKB {GO:0043005=PMID:10918068, GO:0035020=GO_REF:0000024, GO:0005886=Reactome:REACT_20670, GO:0007616=PMID:10918068, GO:0007264=GO_REF:0000002, GO:0035023=GO_REF:0000002, GO:0008283=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0046579=GO_REF:0000024, GO:0046578=GO_REF:0000024, GO:0032863=GO_REF:0000024, GO:0031175=GO_REF:0000024, GO:0005829=GO_REF:0000024, GO:0030426=GO_REF:0000024, GO:0005085=PMID:1379731, GO:0005622=GO_REF:0000002, GO:0007165=PMID:7684828, GO:0005543=GO_REF:0000002, GO:0032320=GO_REF:0000024, GO:0048168=GO_REF:0000019, GO:0048167=GO_REF:0000024, GO:0035254=GO_REF:0000019, GO:0005089=GO_REF:0000002, GO:0005088=PMID:7684828} Q13972 Ras-specific guanine nucleotide-releasing factor 1 protein 20090929 {GO:0043005=NAS, GO:0035020=ISS, GO:0005886=TAS, GO:0007616=NAS, GO:0007264=IEA, GO:0035023=IEA, GO:0008283=IEA, GO:0007268=TAS, GO:0046579=ISS, GO:0046578=ISS, GO:0032863=ISS, GO:0031175=ISS, GO:0005829=ISS, GO:0030426=ISS, GO:0005085=TAS, GO:0005622=IEA, GO:0007165=TAS, GO:0005543=IEA, GO:0032320=ISS, GO:0048168=IEA, GO:0048167=ISS, GO:0035254=IEA, GO:0005089=IEA, GO:0005088=TAS} activation of Rac GTPase activity, cell proliferation, long-term memory, neuron projection development, positive regulation of Ras GTPase activity, positive regulation of Ras protein signal transduction, regulation of Rac protein signal transduction, regulation of Ras protein signal transduction, regulation of Rho protein signal transduction, regulation of neuronal synaptic plasticity, regulation of synaptic plasticity, signal transduction, small GTPase mediated signal transduction, synaptic transmission cytosol, growth cone, intracellular, neuron projection, plasma membrane Ras guanyl-nucleotide exchange factor activity, Rho guanyl-nucleotide exchange factor activity, glutamate receptor binding, guanyl-nucleotide exchange factor activity, phospholipid binding Human RASGRF2 HPA UniProtKB {GO:0005516=GO_REF:0000037, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0005886=Reactome:REACT_20670, GO:0007264=Reactome:REACT_11044, GO:0035023=GO_REF:0000002, GO:0006915=Reactome:REACT_13638, GO:0007268=Reactome:REACT_13685, GO:0097190=Reactome:REACT_13720, GO:0005829=Reactome:REACT_19216, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0005089=GO_REF:0000002} O14827 Ras-specific guanine nucleotide-releasing factor 2 protein 20100326 {GO:0005516=IEA, GO:0051056=TAS, GO:0048011=TAS, GO:0005886=TAS, GO:0007264=TAS, GO:0035023=IEA, GO:0006915=TAS, GO:0007268=TAS, GO:0097190=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0005543=IEA, GO:0005789=IEA, GO:0005089=IEA} apoptotic process, apoptotic signaling pathway, neurotrophin TRK receptor signaling pathway, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction, synaptic transmission cytoplasm, cytosol, endoplasmic reticulum membrane, plasma membrane Rho guanyl-nucleotide exchange factor activity, calmodulin binding, phospholipid binding Human RASGRP1 Reactome UniProtKB {GO:0051056=GO_REF:0000002, GO:0005886=Reactome:REACT_118807, GO:0007264=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0030168=Reactome:REACT_798, GO:0007265=PMID:9582122, GO:0030154=GO_REF:0000037, GO:0008289=PMID:9582122, GO:0005829=Reactome:REACT_15507, GO:0005622=GO_REF:0000002, GO:0005085=Reactome:REACT_118807, GO:0007165=PMID:9789079, GO:0000139=GO_REF:0000039, GO:0016020=PMID:9582122, GO:0007596=Reactome:REACT_604, GO:0005789=GO_REF:0000039} O95267 RAS guanyl-releasing protein 1 protein 20130301 {GO:0051056=IEA, GO:0005886=TAS, GO:0007264=IEA, GO:0005509=IEA, GO:0030168=TAS, GO:0007265=TAS, GO:0030154=IEA, GO:0008289=TAS, GO:0005829=TAS, GO:0005622=IEA, GO:0005085=TAS, GO:0007165=TAS, GO:0000139=IEA, GO:0016020=TAS, GO:0007596=TAS, GO:0005789=IEA} Ras protein signal transduction, blood coagulation, cell differentiation, platelet activation, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction Golgi membrane, cytosol, endoplasmic reticulum membrane, intracellular, membrane, plasma membrane calcium ion binding, guanyl-nucleotide exchange factor activity, lipid binding Human RASGRP2 Reactome UniProtKB {GO:0051056=GO_REF:0000002, GO:0043005=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0005886=PMID:10918068, GO:0007264=GO_REF:0000002, GO:0005509=PMID:9789079, GO:0030168=Reactome:REACT_798, GO:0045202=GO_REF:0000037, GO:0007265=PMID:10918068, GO:0032587=GO_REF:0000039, GO:0001558=PMID:10918068, GO:0019992=PMID:10918068, GO:0005829=Reactome:REACT_15507, GO:0008289=PMID:9789079, GO:0005622=GO_REF:0000002, GO:0005085=PMID:9789079, GO:0007165=PMID:9789079, GO:0007596=Reactome:REACT_604} Q7LDG7 RAS guanyl-releasing protein 2 protein 20130301 {GO:0051056=IEA, GO:0043005=IEA, GO:0030054=IEA, GO:0005886=IDA, GO:0007264=IEA, GO:0005509=TAS, GO:0030168=TAS, GO:0045202=IEA, GO:0007265=NAS, GO:0032587=IEA, GO:0001558=NAS, GO:0019992=NAS, GO:0005829=TAS, GO:0008289=TAS, GO:0005622=IEA, GO:0005085=TAS, GO:0007165=TAS, GO:0007596=TAS} Ras protein signal transduction, blood coagulation, platelet activation, regulation of cell growth, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cell junction, cytosol, intracellular, neuron projection, plasma membrane, ruffle membrane, synapse calcium ion binding, diacylglycerol binding, guanyl-nucleotide exchange factor activity, lipid binding Human RASGRP3 GOC UniProtKB {GO:0051056=GO_REF:0000002, GO:0048471=GO_REF:0000019, GO:0005886=Reactome:REACT_118807, GO:0007264=PMID:10934204, GO:0005509=PMID:10934204, GO:0007265=GO_REF:0000019, GO:0032854=PMID:10934204, GO:0043087=GO_REF:0000019, GO:0019992=PMID:10934204, GO:0005622=GO_REF:0000002, GO:0005085=Reactome:REACT_118807, GO:0046582=PMID:10934204, GO:0000165=PMID:10934204, GO:0005887=PMID:10934204, GO:0004871=PMID:10934204, GO:0019900=GO_REF:0000019, GO:0017016=GO_REF:0000019, GO:0005088=GO_REF:0000019, GO:0032045=GO_REF:0000019} Q8IV61 Ras guanyl-releasing protein 3 protein 20130413 {GO:0051056=IEA, GO:0048471=IEA, GO:0005886=TAS, GO:0007264=TAS, GO:0005509=NAS, GO:0007265=IEA, GO:0032854=IDA, GO:0043087=IEA, GO:0019992=NAS, GO:0005622=IEA, GO:0005085=TAS, GO:0046582=IDA, GO:0000165=NAS, GO:0005887=NAS, GO:0004871=TAS, GO:0019900=IEA, GO:0017016=IEA, GO:0005088=IEA, GO:0032045=IEA} MAPK cascade, Ras protein signal transduction, positive regulation of Rap GTPase activity, regulation of GTPase activity, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction guanyl-nucleotide exchange factor complex, integral to plasma membrane, intracellular, perinuclear region of cytoplasm, plasma membrane Rap GTPase activator activity, Ras GTPase binding, Ras guanyl-nucleotide exchange factor activity, calcium ion binding, diacylglycerol binding, guanyl-nucleotide exchange factor activity, kinase binding, signal transducer activity Human RASGRP4 HPA UniProtKB {GO:0051056=GO_REF:0000002, GO:0005886=PMID:11880369, GO:0007264=GO_REF:0000002, GO:0008283=PMID:11880369, GO:0005509=GO_REF:0000002, GO:0009991=PMID:11880369, GO:0005634=GO_REF:0000052, GO:0046579=PMID:11880369, GO:0007202=PMID:11880369, GO:0019992=PMID:11880369, GO:0005085=GO_REF:0000038, GO:0005737=GO_REF:0000052, GO:0030742=PMID:11880369, GO:0008277=PMID:11880369, GO:0016020=PMID:11880369, GO:0016049=PMID:11880369, GO:0030099=PMID:11880369, GO:0007169=PMID:11880369, GO:0005088=PMID:11880369} Q8TDF6 RAS guanyl-releasing protein 4 protein 20111111 {GO:0051056=IEA, GO:0005886=TAS, GO:0007264=IEA, GO:0008283=IDA, GO:0005509=IEA, GO:0009991=IDA, GO:0005634=IDA, GO:0046579=IDA, GO:0007202=NAS, GO:0019992=TAS, GO:0005085=IEA, GO:0005737=IDA, GO:0030742=NAS, GO:0008277=NAS, GO:0016020=IDA, GO:0016049=IDA, GO:0030099=TAS, GO:0007169=NAS, GO:0005088=IDA} activation of phospholipase C activity, cell growth, cell proliferation, myeloid cell differentiation, positive regulation of Ras protein signal transduction, regulation of G-protein coupled receptor protein signaling pathway, regulation of small GTPase mediated signal transduction, response to extracellular stimulus, small GTPase mediated signal transduction, transmembrane receptor protein tyrosine kinase signaling pathway cytoplasm, membrane, nucleus, plasma membrane GTP-dependent protein binding, Ras guanyl-nucleotide exchange factor activity, calcium ion binding, diacylglycerol binding, guanyl-nucleotide exchange factor activity Human RASIP1 BHF-UCL UniProtKB {GO:0007165=GO_REF:0000002, GO:0048471=GO_REF:0000039, GO:0005795=GO_REF:0000039, GO:0010507=PMID:22354037, GO:0048754=GO_REF:0000024, GO:0001525=GO_REF:0000024, GO:0032319=GO_REF:0000024, GO:0001570=GO_REF:0000024} Q5U651 Ras-interacting protein 1 protein 20120531 {GO:0007165=IEA, GO:0048471=IEA, GO:0005795=IEA, GO:0010507=IMP, GO:0048754=ISS, GO:0001525=ISS, GO:0032319=ISS, GO:0001570=ISS} angiogenesis, branching morphogenesis of an epithelial tube, negative regulation of autophagy, regulation of Rho GTPase activity, signal transduction, vasculogenesis Golgi stack, perinuclear region of cytoplasm Human RASL10B UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0090277=GO_REF:0000024, GO:0003924=GO_REF:0000002, GO:0003050=GO_REF:0000024, GO:0005525=GO_REF:0000037} Q96S79 Ras-like protein family member 10B protein 20120717 {GO:0005886=IEA, GO:0007264=IEA, GO:0090277=ISS, GO:0003924=IEA, GO:0003050=ISS, GO:0005525=IEA} positive regulation of peptide hormone secretion, regulation of systemic arterial blood pressure by atrial natriuretic peptide, small GTPase mediated signal transduction plasma membrane GTP binding, GTPase activity Human UniProtKB:Q5SSG5 RASL11A UniProtKB UniProtKB {GO:0016020=GO_REF:0000002, GO:0045943=GO_REF:0000024, GO:0007264=GO_REF:0000002, GO:0005730=GO_REF:0000024, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6T310 Ras-like protein family member 11A protein 20100224 {GO:0016020=IEA, GO:0045943=ISS, GO:0007264=IEA, GO:0005730=ISS, GO:0003924=IEA, GO:0005525=IEA, GO:0006351=IEA} positive regulation of transcription from RNA polymerase I promoter, small GTPase mediated signal transduction, transcription, DNA-dependent membrane, nucleolus GTP binding, GTPase activity Human UniProtKB:Q6IMB1 RASL11B UniProtKB UniProtKB {GO:0016020=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q9BPW5 Ras-like protein family member 11B protein 20130413 {GO:0016020=IEA, GO:0007264=IEA, GO:0003924=IEA, GO:0005525=IEA} small GTPase mediated signal transduction membrane GTP binding, GTPase activity Human UniProtKB-KW:KW-0342 RASL12 UniProtKB UniProtKB {GO:0016020=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q9NYN1 Ras-like protein family member 12 protein 20130413 {GO:0016020=IEA, GO:0007264=IEA, GO:0003924=IEA, GO:0005525=IEA} small GTPase mediated signal transduction membrane GTP binding, GTPase activity Human UniProtKB-KW:KW-0342 RASSF1 HPA UniProtKB {GO:0005515=PMID:20562859, GO:0005737=GO_REF:0000052, GO:0000922=GO_REF:0000039, GO:0005886=GO_REF:0000052, GO:0005815=GO_REF:0000039, GO:0015630=PMID:14743218, GO:0005874=GO_REF:0000037, GO:0005634=PMID:14743218, GO:0007265=PMID:15109305, GO:0008270=PMID:11333291, GO:0007050=PMID:12024041} Q9NS23 Ras association domain-containing protein 1 protein 20110516 {GO:0005515=IPI, GO:0005737=IDA, GO:0000922=IEA, GO:0005886=IDA, GO:0005815=IEA, GO:0015630=IDA, GO:0005874=IEA, GO:0005634=IDA, GO:0007265=IDA, GO:0008270=TAS, GO:0007050=IMP} Ras protein signal transduction, cell cycle arrest cytoplasm, microtubule, microtubule cytoskeleton, microtubule organizing center, nucleus, plasma membrane, spindle pole protein binding, zinc ion binding Human RASSF2 IntAct UniProtKB {GO:0005515=PMID:23455922, GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0007049=GO_REF:0000037, GO:0005634=GO_REF:0000039} P50749 Ras association domain-containing protein 2 protein 20130415 {GO:0005515=IPI, GO:0007165=IEA, GO:0005737=IEA, GO:0007049=IEA, GO:0005634=IEA} cell cycle, signal transduction cytoplasm, nucleus protein binding Human UniProtKB:Q13043 RASSF3 HPA UniProtKB {GO:0005515=PMID:23455922, GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005874=GO_REF:0000037, GO:0042802=PMID:20920251} Q86WH2 Ras association domain-containing protein 3 protein 20110516 {GO:0005515=IPI, GO:0007165=IEA, GO:0005737=IDA, GO:0005886=IDA, GO:0005874=IEA, GO:0042802=IPI} signal transduction cytoplasm, microtubule, plasma membrane identical protein binding, protein binding Human RASSF4 IntAct UniProtKB {GO:0005515=PMID:23455922, GO:0007165=GO_REF:0000002, GO:0007049=GO_REF:0000037} Q9H2L5 Ras association domain-containing protein 4 protein 20130415 {GO:0005515=IPI, GO:0007165=IEA, GO:0007049=IEA} cell cycle, signal transduction protein binding Human UniProtKB:Q13043 RASSF5 IntAct UniProtKB {GO:0005515=PMID:23455922, GO:0035556=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0005874=GO_REF:0000037, GO:0006915=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q8WWW0 Ras association domain-containing protein 5 protein 20130415 {GO:0005515=IPI, GO:0035556=IEA, GO:0005737=IEA, GO:0005874=IEA, GO:0006915=IEA, GO:0046872=IEA} apoptotic process, intracellular signal transduction cytoplasm, microtubule metal ion binding, protein binding Human UniProtKB:Q13188 RASSF6 IntAct UniProtKB {GO:0005515=PMID:20920251, GO:0007165=GO_REF:0000002, GO:0006915=GO_REF:0000037, GO:0042981=GO_REF:0000019} Q6ZTQ3 Ras association domain-containing protein 6 protein 20130415 {GO:0005515=IPI, GO:0007165=IEA, GO:0006915=IEA, GO:0042981=IEA} apoptotic process, regulation of apoptotic process, signal transduction protein binding Human UniProtKB:Q13043 RASSF7 UniProtKB UniProtKB {GO:0007165=GO_REF:0000002, GO:0006355=GO_REF:0000029, GO:0005737=GO_REF:0000037, GO:0005815=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000029, GO:0003677=GO_REF:0000029} Q02833 Ras association domain-containing protein 7 protein 20021106 {GO:0007165=IEA, GO:0006355=NAS, GO:0005737=IEA, GO:0005815=IEA, GO:0006915=IEA, GO:0005634=NAS, GO:0003677=NAS} apoptotic process, regulation of transcription, DNA-dependent, signal transduction cytoplasm, microtubule organizing center, nucleus DNA binding Human RASSF8 InterPro UniProtKB {GO:0007165=GO_REF:0000002} Q8NHQ8 Ras association domain-containing protein 8 protein 20130413 {GO:0007165=IEA} signal transduction Human InterPro:IPR000159 RASSF9 UniProtKB UniProtKB {GO:0005515=PMID:9837933, GO:0005215=PMID:9837933, GO:0007165=GO_REF:0000002, GO:0016197=PMID:9837933, GO:0006605=PMID:9837933, GO:0012510=PMID:9837933, GO:0005829=PMID:9837933, GO:0005768=PMID:9837933} O75901 Ras association domain-containing protein 9 protein 20031216 {GO:0005515=IPI, GO:0005215=NAS, GO:0007165=IEA, GO:0016197=NAS, GO:0006605=NAS, GO:0012510=IDA, GO:0005829=IDA, GO:0005768=IDA} endosomal transport, protein targeting, signal transduction cytosol, endosome, trans-Golgi network transport vesicle membrane protein binding, transporter activity Human RAVER1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002} Q8IY67 Ribonucleoprotein PTB-binding 1 protein 20130413 {GO:0005737=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0003676=IEA} cytoplasm, nucleus RNA binding, nucleic acid binding, nucleotide binding Human UniProtKB-SubCell:SL-0086 RAVER2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0030529=GO_REF:0000038, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000038} Q9HCJ3 Ribonucleoprotein PTB-binding 2 protein 20130413 {GO:0005737=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0030529=IEA, GO:0005634=IEA, GO:0003676=IEA} cytoplasm, nucleus, ribonucleoprotein complex RNA binding, nucleic acid binding, nucleotide binding Human UniProtKB-SubCell:SL-0086 RAX PINC UniProtKB {GO:0043565=GO_REF:0000002, GO:0007389=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0060173=GO_REF:0000019, GO:0043010=GO_REF:0000019, GO:0021854=GO_REF:0000019, GO:0007601=PMID:10625658, GO:0003677=GO_REF:0000038, GO:0006351=GO_REF:0000037} Q9Y2V3 Retinal homeobox protein Rx protein 20030904 {GO:0043565=IEA, GO:0007389=IEA, GO:0003700=IEA, GO:0005634=IEA, GO:0060173=IEA, GO:0043010=IEA, GO:0021854=IEA, GO:0007601=TAS, GO:0003677=IEA, GO:0006351=IEA} camera-type eye development, hypothalamus development, limb development, pattern specification process, transcription, DNA-dependent, visual perception nucleus DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human RAX2 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0007601=GO_REF:0000037, GO:0050896=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96IS3 Retina and anterior neural fold homeobox protein 2 protein 20130413 {GO:0043565=IEA, GO:0003700=IEA, GO:0005634=IEA, GO:0007601=IEA, GO:0050896=IEA, GO:0006351=IEA} response to stimulus, transcription, DNA-dependent, visual perception nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0191 RB1 UniProtKB UniProtKB {GO:0005515=PMID:16964284, GO:0051219=PMID:16360038, GO:0003700=PMID:3657987, GO:0050680=GO_REF:0000019, GO:0071922=PMID:20551165, GO:0050681=PMID:15572661, GO:0051402=GO_REF:0000019, GO:0043353=GO_REF:0000019, GO:0031175=GO_REF:0000019, GO:0035189=PMID:19149898, GO:0045445=PMID:15541338, GO:0000785=PMID:3657987, GO:0031625=PMID:10944455, GO:0001102=GO_REF:0000019, GO:0003713=PMID:15572661, GO:0045842=PMID:20551165, GO:0005819=GO_REF:0000019, GO:0043550=PMID:16286473, GO:0001047=PMID:15735762, GO:0031134=PMID:20551165, GO:0045651=GO_REF:0000019, GO:0071930=GO_REF:0000019, GO:0045749=PMID:19149898, GO:0000075=PMID:10825186, GO:0005654=Reactome:REACT_9050, GO:0045893=PMID:15572661, GO:0000278=Reactome:REACT_152, GO:0045892=PMID:12065415, GO:0051146=GO_REF:0000019, GO:0051301=GO_REF:0000019, GO:0008134=PMID:19223331, GO:0007093=PMID:9529249, GO:0007265=PMID:9054499, GO:0045879=GO_REF:0000019, GO:0005634=PMID:17540172, GO:0043433=PMID:9529249, GO:0000084=Reactome:REACT_899, GO:0003674=GO_REF:0000015, GO:0000082=Reactome:REACT_1783, GO:0000083=PMID:19149898, GO:0048667=GO_REF:0000019, GO:0016514=PMID:19149898, GO:0045944=GO_REF:0000019, GO:0006338=PMID:19149898, GO:0007050=PMID:19149898, GO:0019900=PMID:16286473, GO:0000080=Reactome:REACT_1590, GO:0090230=PMID:20551165, GO:0042551=GO_REF:0000019, GO:0048565=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0071459=PMID:20551165, GO:0003677=PMID:3657987, GO:0006351=GO_REF:0000037, GO:0008150=GO_REF:0000015, GO:0007346=PMID:20551165, GO:0016605=PMID:9448006, GO:0019048=GO_REF:0000037, GO:0034088=PMID:20551165, GO:0006469=PMID:9858607, GO:0030521=PMID:15572661} Q92728 Mutated retinoblastoma protein protein 20111129 {GO:0005515=IPI, GO:0051219=IPI, GO:0003700=TAS, GO:0050680=IEA, GO:0071922=IMP, GO:0050681=NAS, GO:0051402=IEA, GO:0043353=IEA, GO:0031175=IEA, GO:0035189=TAS, GO:0045445=IMP, GO:0000785=TAS, GO:0031625=IPI, GO:0001102=IEA, GO:0003713=NAS, GO:0045842=IMP, GO:0005819=IEA, GO:0043550=IDA, GO:0001047=IDA, GO:0031134=IMP, GO:0045651=IEA, GO:0071930=IEA, GO:0045749=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0045893=NAS, GO:0000278=TAS, GO:0045892=IDA, GO:0051146=IEA, GO:0051301=IEA, GO:0008134=IPI, GO:0007093=TAS, GO:0007265=IEP, GO:0045879=IEA, GO:0005634=IDA, GO:0043433=TAS, GO:0000084=TAS, GO:0003674=ND, GO:0000082=TAS, GO:0000083=TAS, GO:0048667=IEA, GO:0016514=TAS, GO:0045944=IEA, GO:0006338=TAS, GO:0007050=TAS, GO:0019900=IDA, GO:0000080=TAS, GO:0090230=TAS, GO:0042551=IEA, GO:0048565=IEA, GO:0005575=ND, GO:0071459=IMP, GO:0003677=TAS, GO:0006351=IEA, GO:0008150=ND, GO:0007346=IMP, GO:0016605=IDA, GO:0019048=IEA, GO:0034088=IMP, GO:0006469=IPI, GO:0030521=NAS} G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, Ras protein signal transduction, S phase of mitotic cell cycle, androgen receptor signaling pathway, biological_process, cell cycle arrest, cell cycle checkpoint, cell division, cell morphogenesis involved in neuron differentiation, chromatin remodeling, digestive tract development, enucleate erythrocyte differentiation, maintenance of mitotic sister chromatid cohesion, mitotic cell cycle, mitotic cell cycle checkpoint, myoblast differentiation, negative regulation of S phase of mitotic cell cycle, negative regulation of epithelial cell proliferation, negative regulation of protein kinase activity, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of smoothened signaling pathway, negative regulation of transcription involved in G1/S phase of mitotic cell cycle, negative regulation of transcription, DNA-dependent, neuron apoptotic process, neuron maturation, neuron projection development, positive regulation of macrophage differentiation, positive regulation of mitotic metaphase/anaphase transition, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein localization to chromosome, centromeric region, regulation of centromere complex assembly, regulation of cohesin localization to chromatin, regulation of lipid kinase activity, regulation of mitotic cell cycle, regulation of transcription involved in G1/S phase of mitotic cell cycle, sister chromatid biorientation, striated muscle cell differentiation, transcription, DNA-dependent, virus-host interaction PML body, Rb-E2F complex, SWI/SNF complex, cellular_component, chromatin, nucleoplasm, nucleus, spindle DNA binding, RNA polymerase II activating transcription factor binding, androgen receptor binding, core promoter binding, kinase binding, molecular_function, phosphoprotein binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, transcription factor binding, ubiquitin protein ligase binding Human RB1CC1 IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0043066=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0019901=GO_REF:0000019, GO:0007254=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037, GO:0005829=GO_REF:0000039, GO:0001889=GO_REF:0000019, GO:0007507=GO_REF:0000019, GO:0045793=GO_REF:0000019, GO:0007049=GO_REF:0000037, GO:0034045=GO_REF:0000024, GO:0070969=PMID:19211835, GO:0001934=GO_REF:0000019, GO:0010506=GO_REF:0000024, GO:0000045=GO_REF:0000019} Q8TDY2 RB1-inducible coiled-coil protein 1 protein 20130415 {GO:0005515=IPI, GO:0043066=IEA, GO:0006355=IEA, GO:0019901=IEA, GO:0007254=IEA, GO:0005634=IEA, GO:0006351=IEA, GO:0005829=IEA, GO:0001889=IEA, GO:0007507=IEA, GO:0045793=IEA, GO:0007049=IEA, GO:0034045=ISS, GO:0070969=IPI, GO:0001934=IEA, GO:0010506=ISS, GO:0000045=IEA} JNK cascade, autophagic vacuole assembly, cell cycle, heart development, liver development, negative regulation of apoptotic process, positive regulation of cell size, positive regulation of protein phosphorylation, regulation of autophagy, regulation of transcription, DNA-dependent, transcription, DNA-dependent ULK1-ATG13-FIP200 complex, cytosol, nucleus, pre-autophagosomal structure membrane protein binding, protein kinase binding Human UniProtKB:A7MCY6 RBAK UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=PMID:10702291, GO:0008270=PMID:10702291, GO:0005634=PMID:10702291, GO:0003676=GO_REF:0000002, GO:0045892=PMID:10702291, GO:0006351=GO_REF:0000037} Q9NYW8 RB-associated KRAB zinc finger protein protein 20010905 {GO:0005622=IEA, GO:0006355=TAS, GO:0008270=NAS, GO:0005634=TAS, GO:0003676=IEA, GO:0045892=TAS, GO:0006351=IEA} negative regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus nucleic acid binding, zinc ion binding Human RBBP4 BHF-UCL UniProtKB {GO:0005515=PMID:21047798, GO:0006355=GO_REF:0000037, GO:0033186=PMID:8858152, GO:0008285=PMID:8350924, GO:0042826=PMID:17827154, GO:0006334=Reactome:REACT_22344, GO:0005634=PMID:14609955, GO:0006351=GO_REF:0000037, GO:0034080=Reactome:REACT_22186, GO:0006260=GO_REF:0000037, GO:0042393=PMID:17827154, GO:0035098=PMID:23273982, GO:0016581=PMID:17827154, GO:0031497=PMID:8858152, GO:0016580=PMID:17827154, GO:0005654=Reactome:REACT_111236, GO:0006338=PMID:14609955, GO:0000278=Reactome:REACT_152, GO:0016589=PMID:20850016, GO:0008094=PMID:14609955} Q09028 Histone-binding protein RBBP4 protein 20090625 {GO:0005515=IPI, GO:0006355=IEA, GO:0033186=IDA, GO:0008285=TAS, GO:0042826=IPI, GO:0006334=TAS, GO:0005634=IDA, GO:0006351=IEA, GO:0034080=TAS, GO:0006260=IEA, GO:0042393=NAS, GO:0035098=IDA, GO:0016581=NAS, GO:0031497=IDA, GO:0016580=NAS, GO:0005654=TAS, GO:0006338=IDA, GO:0000278=TAS, GO:0016589=IDA, GO:0008094=IDA} CENP-A containing nucleosome assembly at centromere, DNA replication, chromatin assembly, chromatin remodeling, mitotic cell cycle, negative regulation of cell proliferation, nucleosome assembly, regulation of transcription, DNA-dependent, transcription, DNA-dependent CAF-1 complex, ESC/E(Z) complex, NURF complex, NuRD complex, Sin3 complex, nucleoplasm, nucleus DNA-dependent ATPase activity, histone binding, histone deacetylase binding, protein binding Human UniProtKB:Q92769 RBBP5 IntAct UniProtKB {GO:0005515=PMID:19556245, GO:0006355=GO_REF:0000037, GO:0043627=PMID:16603732, GO:0044212=PMID:16603732, GO:0005634=PMID:17500065, GO:0035064=PMID:15960975, GO:0042800=PMID:17355966, GO:0006351=GO_REF:0000037, GO:0006974=PMID:17500065, GO:0035097=PMID:14992727, GO:0048188=PMID:18838538, GO:0071339=PMID:15960975, GO:0051568=PMID:17355966} Q15291 Retinoblastoma-binding protein 5 protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0043627=IDA, GO:0044212=IDA, GO:0005634=IDA, GO:0035064=IDA, GO:0042800=IDA, GO:0006351=IEA, GO:0006974=IDA, GO:0035097=IPI, GO:0048188=IDA, GO:0071339=IDA, GO:0051568=IDA} histone H3-K4 methylation, regulation of transcription, DNA-dependent, response to DNA damage stimulus, response to estrogen stimulus, transcription, DNA-dependent MLL1 complex, Set1C/COMPASS complex, histone methyltransferase complex, nucleus histone methyltransferase activity (H3-K4 specific), methylated histone residue binding, protein binding, transcription regulatory region DNA binding Human UniProtKB:Q9UBL3 RBBP6 UniProtKB UniProtKB {GO:0005515=PMID:18851979, GO:0004842=PMID:18851979, GO:0005737=GO_REF:0000037, GO:0042787=PMID:18851979, GO:0005815=GO_REF:0000039, GO:0005694=GO_REF:0000039, GO:0005730=GO_REF:0000039, GO:0005634=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q7Z6E9 E3 ubiquitin-protein ligase RBBP6 protein 20110414 {GO:0005515=IPI, GO:0004842=IDA, GO:0005737=IEA, GO:0042787=IDA, GO:0005815=IEA, GO:0005694=IEA, GO:0005730=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA} protein ubiquitination involved in ubiquitin-dependent protein catabolic process chromosome, cytoplasm, microtubule organizing center, nucleolus, nucleus nucleic acid binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human RBBP7 ENSEMBL UniProtKB {GO:0005515=PMID:19497860, GO:0030308=PMID:9765217, GO:0008283=PMID:7503932, GO:0006334=Reactome:REACT_22344, GO:0005634=GO_REF:0000019, GO:0007275=PMID:7503932, GO:0000122=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0034080=Reactome:REACT_22186, GO:0006260=GO_REF:0000037, GO:0035098=PMID:23273982, GO:0016581=PMID:19644445, GO:0005654=Reactome:REACT_22217, GO:0070370=PMID:7503932} Q5JNZ6 Histone-binding protein RBBP7 protein 20130413 {GO:0005515=IPI, GO:0030308=IDA, GO:0008283=TAS, GO:0006334=TAS, GO:0005634=IEA, GO:0007275=TAS, GO:0000122=IEA, GO:0006351=IEA, GO:0034080=TAS, GO:0006260=IEA, GO:0035098=IDA, GO:0016581=IDA, GO:0005654=TAS, GO:0070370=IDA} CENP-A containing nucleosome assembly at centromere, DNA replication, cell proliferation, cellular heat acclimation, multicellular organismal development, negative regulation of cell growth, negative regulation of transcription from RNA polymerase II promoter, nucleosome assembly, transcription, DNA-dependent ESC/E(Z) complex, NuRD complex, nucleoplasm, nucleus protein binding Human Ensembl:ENSMUSP00000033720 RBBP8 GOC UniProtKB {GO:0001103=PMID:16287852, GO:0005515=PMID:16287852, GO:0006357=PMID:10764811, GO:0001106=PMID:16287852, GO:0001835=GO_REF:0000019, GO:0031572=PMID:15485915, GO:0010792=PMID:18716619, GO:0005634=PMID:10764811, GO:0000122=PMID:16287852, GO:0003684=PMID:18716619, GO:0000082=GO_REF:0000019, GO:0007067=GO_REF:0000037, GO:0006281=PMID:10764811, GO:0007126=GO_REF:0000037, GO:0000724=PMID:20829486, GO:0017053=PMID:16287852, GO:0000014=PMID:18716619, GO:0000075=PMID:10764811, GO:0051301=GO_REF:0000037} Q99708 DNA endonuclease RBBP8 protein 20130413 {GO:0001103=IPI, GO:0005515=IPI, GO:0006357=TAS, GO:0001106=IDA, GO:0001835=IEA, GO:0031572=IDA, GO:0010792=IMP, GO:0005634=TAS, GO:0000122=IDA, GO:0003684=IDA, GO:0000082=IEA, GO:0007067=IEA, GO:0006281=TAS, GO:0007126=IEA, GO:0000724=IDA, GO:0017053=IDA, GO:0000014=IMP, GO:0000075=TAS, GO:0051301=IEA} DNA double-strand break processing involved in repair via single-strand annealing, DNA repair, G1/S transition of mitotic cell cycle, G2 DNA damage checkpoint, blastocyst hatching, cell cycle checkpoint, cell division, double-strand break repair via homologous recombination, meiosis, mitosis, negative regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter nucleus, transcriptional repressor complex RNA polymerase II repressing transcription factor binding, RNA polymerase II transcription corepressor activity, damaged DNA binding, protein binding, single-stranded DNA specific endodeoxyribonuclease activity Human RBBP9 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0016787=GO_REF:0000037, GO:0042127=GO_REF:0000019, GO:0005634=GO_REF:0000052} O75884 Putative hydrolase RBBP9 protein 20100326 {GO:0005737=IDA, GO:0016787=IEA, GO:0042127=IEA, GO:0005634=IDA} regulation of cell proliferation cytoplasm, nucleus hydrolase activity Human RBCK1 IntAct UniProtKB {GO:0000209=PMID:12629548, GO:0005515=PMID:21903422, GO:0050852=PMID:20005846, GO:0042346=GO_REF:0000019, GO:0043130=PMID:21455181, GO:0004842=PMID:12629548, GO:0043065=GO_REF:0000019, GO:0032088=PMID:17449468, GO:0071797=PMID:21455181, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000002, GO:0097039=PMID:21455181, GO:0005622=GO_REF:0000002, GO:0051092=PMID:19136968, GO:0019048=GO_REF:0000037, GO:0043161=PMID:17449468, GO:0008270=GO_REF:0000002, GO:0043123=PMID:19136968} Q9BYM8 RanBP-type and C3HC4-type zinc finger-containing protein 1 protein 20130415 {GO:0000209=IDA, GO:0005515=IPI, GO:0050852=IDA, GO:0042346=IEA, GO:0043130=IDA, GO:0004842=IDA, GO:0043065=IEA, GO:0032088=IDA, GO:0071797=IDA, GO:0003677=IEA, GO:0006351=IEA, GO:0097039=IDA, GO:0005622=IEA, GO:0051092=IDA, GO:0019048=IEA, GO:0043161=IMP, GO:0008270=IEA, GO:0043123=IDA} T cell receptor signaling pathway, negative regulation of NF-kappaB transcription factor activity, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB import into nucleus, positive regulation of NF-kappaB transcription factor activity, positive regulation of apoptotic process, proteasomal ubiquitin-dependent protein catabolic process, protein linear polyubiquitination, protein polyubiquitination, transcription, DNA-dependent, virus-host interaction LUBAC complex, intracellular DNA binding, protein binding, ubiquitin binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q4VA12 RBFA BHF-UCL UniProtKB {GO:0005739=GO_REF:0000039, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0006364=GO_REF:0000037, GO:0005575=GO_REF:0000015} Q8N0V3 Putative ribosome-binding factor A, mitochondrial protein 20120710 {GO:0005739=IEA, GO:0008150=ND, GO:0003674=ND, GO:0006364=IEA, GO:0005575=ND} biological_process, rRNA processing cellular_component, mitochondrion molecular_function Human RBFOX1 IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0003723=PMID:10814712, GO:0050658=PMID:10814712, GO:0005634=GO_REF:0000039, GO:0043484=GO_REF:0000002, GO:0008022=PMID:10814712, GO:0003676=GO_REF:0000002} Q9NWB1 RNA binding protein fox-1 homolog 1 protein 20130415 {GO:0005515=IPI, GO:0008380=IEA, GO:0006397=IEA, GO:0000166=IEA, GO:0003723=NAS, GO:0050658=NAS, GO:0005634=IEA, GO:0043484=IEA, GO:0008022=IPI, GO:0003676=IEA} RNA splicing, RNA transport, mRNA processing, regulation of RNA splicing nucleus RNA binding, nucleic acid binding, nucleotide binding, protein C-terminus binding, protein binding Human UniProtKB:Q9Y6R0 RBFOX2 HPA UniProtKB {GO:0005515=PMID:23275563, GO:0006397=GO_REF:0000037, GO:0008380=GO_REF:0000037, GO:0016070=PMID:11875103, GO:0003714=PMID:11875103, GO:0003723=PMID:11875103, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0010724=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0000166=GO_REF:0000002, GO:0000381=GO_REF:0000024, GO:0042127=PMID:11875103, GO:0043484=GO_REF:0000002, GO:0045892=PMID:11875103, GO:0008134=PMID:11875103, GO:0030520=PMID:11875103} O43251 RNA binding protein fox-1 homolog 2 protein 20080205 {GO:0005515=IPI, GO:0006397=IEA, GO:0008380=IEA, GO:0016070=TAS, GO:0003714=IDA, GO:0003723=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0010724=IEA, GO:0005737=IDA, GO:0000166=IEA, GO:0000381=ISS, GO:0042127=TAS, GO:0043484=IEA, GO:0045892=IDA, GO:0008134=IDA, GO:0030520=IDA} RNA metabolic process, RNA splicing, intracellular estrogen receptor signaling pathway, mRNA processing, negative regulation of transcription, DNA-dependent, regulation of RNA splicing, regulation of alternative mRNA splicing, via spliceosome, regulation of cell proliferation, regulation of definitive erythrocyte differentiation cytoplasm, nucleolus, nucleus RNA binding, nucleic acid binding, nucleotide binding, protein binding, transcription corepressor activity, transcription factor binding Human RBKS UniPathway UniProtKB {GO:0019303=GO_REF:0000041, GO:0004747=GO_REF:0000003, GO:0005524=GO_REF:0000037, GO:0006014=GO_REF:0000002} Q9H477 Ribokinase protein 20130413 {GO:0019303=IEA, GO:0004747=IEA, GO:0005524=IEA, GO:0006014=IEA} D-ribose catabolic process, D-ribose metabolic process ATP binding, ribokinase activity Human UniPathway:UPA00916 RBL1 IntAct UniProtKB {GO:0005515=PMID:22094256, GO:0010467=Reactome:REACT_71, GO:0005667=GO_REF:0000019, GO:0006367=Reactome:REACT_12627, GO:0043550=PMID:16286473, GO:0005634=GO_REF:0000002, GO:0000122=GO_REF:0000019, GO:0006351=Reactome:REACT_121061, GO:0045944=Reactome:REACT_120734, GO:0019048=GO_REF:0000037, GO:0051726=GO_REF:0000002, GO:0005654=Reactome:REACT_111090, GO:0007179=Reactome:REACT_6844, GO:0000278=Reactome:REACT_152, GO:0000080=Reactome:REACT_1590, GO:0016568=GO_REF:0000037, GO:0008134=PMID:16360038} P28749 Retinoblastoma-like protein 1 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0005667=IEA, GO:0006367=TAS, GO:0043550=IDA, GO:0005634=IEA, GO:0000122=IEA, GO:0006351=TAS, GO:0045944=TAS, GO:0019048=IEA, GO:0051726=IEA, GO:0005654=TAS, GO:0007179=TAS, GO:0000278=TAS, GO:0000080=TAS, GO:0016568=IEA, GO:0008134=IPI} G1 phase of mitotic cell cycle, chromatin modification, gene expression, mitotic cell cycle, negative regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter, regulation of cell cycle, regulation of lipid kinase activity, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, virus-host interaction nucleoplasm, nucleus, transcription factor complex protein binding, transcription factor binding Human UniProtKB:P11802 RBL2 HPA UniProtKB {GO:0005515=PMID:17620057, GO:0005667=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0043550=PMID:16286473, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0051726=GO_REF:0000002, GO:0005654=Reactome:REACT_111236, GO:0000080=Reactome:REACT_1590, GO:0000278=Reactome:REACT_152, GO:0016568=GO_REF:0000037} Q08999 Retinoblastoma-like protein 2 protein 20101115 {GO:0005515=IPI, GO:0005667=IEA, GO:0006355=IEA, GO:0005730=IDA, GO:0043550=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA, GO:0005737=IDA, GO:0051726=IEA, GO:0005654=TAS, GO:0000080=TAS, GO:0000278=TAS, GO:0016568=IEA} G1 phase of mitotic cell cycle, chromatin modification, mitotic cell cycle, regulation of cell cycle, regulation of lipid kinase activity, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleolus, nucleoplasm, nucleus, transcription factor complex DNA binding, protein binding Human RBM10 HPA UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0008150=GO_REF:0000015, GO:0008285=GO_REF:0000019, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000029, GO:0034393=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0000122=GO_REF:0000019, GO:0070935=GO_REF:0000019} P98175 RNA-binding protein 10 protein 20101115 {GO:0008380=IEA, GO:0006397=IEA, GO:0008150=ND, GO:0008285=IEA, GO:0000166=IEA, GO:0003723=NAS, GO:0034393=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0000122=IEA, GO:0070935=IEA} 3'-UTR-mediated mRNA stabilization, RNA splicing, biological_process, mRNA processing, negative regulation of cell proliferation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of smooth muscle cell apoptotic process nucleolus, nucleus RNA binding, nucleotide binding, zinc ion binding NOT Human RBM11 UniProtKB UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0016607=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0007275=GO_REF:0000037, GO:0030154=GO_REF:0000037} P57052 Splicing regulator RBM11 protein 20130413 {GO:0008380=IEA, GO:0006397=IEA, GO:0016607=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0007275=IEA, GO:0030154=IEA} RNA splicing, cell differentiation, mRNA processing, multicellular organismal development nuclear speck RNA binding, nucleotide binding Human UniProtKB-SubCell:SL-0186 RBM12 HPA UniProtKB {GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9NTZ6 RNA-binding protein 12 protein 20120912 {GO:0000166=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA} nucleolus, nucleus RNA binding, nucleotide binding NOT Human RBM12B IntAct UniProtKB {GO:0005515=PMID:21078624, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0003676=GO_REF:0000002} Q8IXT5 RNA-binding protein 12B protein 20130415 {GO:0005515=IPI, GO:0000166=IEA, GO:0003723=IEA, GO:0003676=IEA} RNA binding, nucleic acid binding, nucleotide binding, protein binding Human UniProtKB:O00555 RBM14 HPA UniProtKB {GO:0005515=PMID:15919756, GO:0005667=PMID:11443112, GO:0016575=PMID:11443112, GO:0001104=PMID:11443112, GO:0003723=PMID:11443112, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006310=PMID:11443112, GO:0003676=GO_REF:0000002, GO:0006260=PMID:11443112, GO:0006281=PMID:11443112, GO:0030374=PMID:11443112, GO:0000166=GO_REF:0000002, GO:0016592=PMID:11443112, GO:0045944=PMID:15919756, GO:0030529=PMID:11443112, GO:0042921=PMID:11443112, GO:0009725=PMID:11443112, GO:0030674=PMID:11443112, GO:0030520=PMID:11443112} Q96PK6 RNA-binding protein 14 protein 20080205 {GO:0005515=IPI, GO:0005667=IPI, GO:0016575=IPI, GO:0001104=NAS, GO:0003723=NAS, GO:0005730=IDA, GO:0005634=IDA, GO:0006310=NAS, GO:0003676=IEA, GO:0006260=NAS, GO:0006281=NAS, GO:0030374=IPI, GO:0000166=IEA, GO:0016592=NAS, GO:0045944=IDA, GO:0030529=TAS, GO:0042921=NAS, GO:0009725=TAS, GO:0030674=NAS, GO:0030520=NAS} DNA recombination, DNA repair, DNA replication, glucocorticoid receptor signaling pathway, histone deacetylation, intracellular estrogen receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, response to hormone stimulus mediator complex, nucleolus, nucleus, ribonucleoprotein complex, transcription factor complex RNA binding, RNA polymerase II transcription cofactor activity, ligand-dependent nuclear receptor transcription coactivator activity, nucleic acid binding, nucleotide binding, protein binding, protein binding, bridging NOT Human RBM15 HPA UniProtKB {GO:0005515=PMID:16129689, GO:0001569=GO_REF:0000019, GO:0060674=GO_REF:0000019, GO:0003723=GO_REF:0000037, GO:0060412=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0007221=GO_REF:0000019, GO:0048536=GO_REF:0000019, GO:0000166=GO_REF:0000002, GO:0045638=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0045892=PMID:16129689} Q96T37 Putative RNA-binding protein 15 protein 20100326 {GO:0005515=IPI, GO:0001569=IEA, GO:0060674=IEA, GO:0003723=IEA, GO:0060412=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0007221=IEA, GO:0048536=IEA, GO:0000166=IEA, GO:0045638=IEA, GO:0019048=IEA, GO:0045892=IDA} negative regulation of myeloid cell differentiation, negative regulation of transcription, DNA-dependent, patterning of blood vessels, placenta blood vessel development, positive regulation of transcription of Notch receptor target, spleen development, ventricular septum morphogenesis, virus-host interaction nucleolus, nucleus RNA binding, nucleotide binding, protein binding NOT Human RBM15B HPA UniProtKB {GO:0006397=GO_REF:0000037, GO:0008380=GO_REF:0000037, GO:0005515=PMID:16129689, GO:0003723=PMID:16129689, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037, GO:0006913=PMID:16129689, GO:0000166=GO_REF:0000002, GO:0000381=PMID:16129689, GO:0019048=GO_REF:0000037, GO:0005654=PMID:16129689, GO:0045892=PMID:16129689} Q8NDT2 Putative RNA-binding protein 15B protein 20110516 {GO:0006397=IEA, GO:0008380=IEA, GO:0005515=IPI, GO:0003723=NAS, GO:0005730=IDA, GO:0005634=IDA, GO:0006351=IEA, GO:0006913=IDA, GO:0000166=IEA, GO:0000381=IDA, GO:0019048=IEA, GO:0005654=IDA, GO:0045892=IDA} RNA splicing, mRNA processing, negative regulation of transcription, DNA-dependent, nucleocytoplasmic transport, regulation of alternative mRNA splicing, via spliceosome, transcription, DNA-dependent, virus-host interaction nucleolus, nucleoplasm, nucleus RNA binding, nucleotide binding, protein binding NOT Human RBM17 HPA UniProtKB {GO:0005515=PMID:17577209, GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005681=GO_REF:0000037, GO:0003676=GO_REF:0000002} Q96I25 Splicing factor 45 protein 20111111 {GO:0005515=IPI, GO:0008380=IEA, GO:0006397=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005681=IEA, GO:0003676=IEA} RNA splicing, mRNA processing nucleolus, nucleus, spliceosomal complex RNA binding, nucleic acid binding, nucleotide binding, protein binding NOT Human RBM18 UniProtKB UniProtKB {GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037} Q96H35 Probable RNA-binding protein 18 protein 20130413 {GO:0000166=IEA, GO:0003723=IEA} RNA binding, nucleotide binding Human UniProtKB-KW:KW-0694 RBM19 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0000166=GO_REF:0000002, GO:0005694=GO_REF:0000039, GO:0003723=GO_REF:0000037, GO:0040019=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005654=GO_REF:0000024, GO:0007275=GO_REF:0000037, GO:0003676=GO_REF:0000002} Q9Y4C8 Probable RNA-binding protein 19 protein 20110516 {GO:0005737=IDA, GO:0000166=IEA, GO:0005694=IEA, GO:0003723=IEA, GO:0040019=ISS, GO:0005730=IDA, GO:0005634=IDA, GO:0005654=ISS, GO:0007275=IEA, GO:0003676=IEA} multicellular organismal development, positive regulation of embryonic development chromosome, cytoplasm, nucleolus, nucleoplasm, nucleus RNA binding, nucleic acid binding, nucleotide binding Human RBM22 HPA UniProtKB {GO:0003723=GO_REF:0000038, GO:0045292=PMID:22246180, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0033554=PMID:21122810, GO:0090316=PMID:21122810, GO:0003676=GO_REF:0000002, GO:0071013=PMID:11991638, GO:0033120=PMID:22246180, GO:0005737=PMID:21122810, GO:0000166=GO_REF:0000002, GO:0005487=PMID:21122810, GO:0000398=PMID:11991638, GO:0017069=PMID:22246180, GO:0008270=GO_REF:0000002, GO:0036002=PMID:22246180, GO:0000060=PMID:17045351, GO:0048306=PMID:17045351} Q9NW64 Pre-mRNA-splicing factor RBM22 protein 20080205 {GO:0003723=IEA, GO:0045292=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0033554=IDA, GO:0090316=IDA, GO:0003676=IEA, GO:0071013=IDA, GO:0033120=IDA, GO:0005737=IDA, GO:0000166=IEA, GO:0005487=IDA, GO:0000398=IC, GO:0017069=IDA, GO:0008270=IEA, GO:0036002=IDA, GO:0000060=IDA, GO:0048306=IPI} cellular response to stress, mRNA cis splicing, via spliceosome, mRNA splicing, via spliceosome, positive regulation of RNA splicing, positive regulation of intracellular protein transport, protein import into nucleus, translocation catalytic step 2 spliceosome, cytoplasm, nucleolus, nucleus RNA binding, calcium-dependent protein binding, nucleic acid binding, nucleocytoplasmic transporter activity, nucleotide binding, pre-mRNA binding, snRNA binding, zinc ion binding NOT Human RBM23 UniProtKB UniProtKB {GO:0006397=GO_REF:0000002, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002} Q86U06 Probable RNA-binding protein 23 protein 20130413 {GO:0006397=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0003676=IEA} mRNA processing nucleus RNA binding, nucleic acid binding, nucleotide binding Human UniProtKB-SubCell:SL-0191 RBM24 UniProtKB UniProtKB {GO:0043488=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0010830=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0003730=GO_REF:0000024, GO:0003676=GO_REF:0000002, GO:0030154=GO_REF:0000037} Q9BX46 RNA-binding protein 24 protein 20110221 {GO:0043488=ISS, GO:0005737=IEA, GO:0000166=IEA, GO:0010830=ISS, GO:0005634=IEA, GO:0003730=ISS, GO:0003676=IEA, GO:0030154=IEA} cell differentiation, regulation of mRNA stability, regulation of myotube differentiation cytoplasm, nucleus mRNA 3'-UTR binding, nucleic acid binding, nucleotide binding Human UniProtKB:D3Z4I3 RBM25 HPA UniProtKB {GO:0005515=PMID:18663000, GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0016607=PMID:18663000, GO:0000166=GO_REF:0000002, GO:0000381=PMID:18663000, GO:0005730=GO_REF:0000052, GO:0006915=PMID:18663000, GO:0005634=GO_REF:0000052, GO:0003729=PMID:18663000, GO:0003676=GO_REF:0000002} P49756 RNA-binding protein 25 protein 20080205 {GO:0005515=IPI, GO:0008380=IEA, GO:0006397=IEA, GO:0005737=IDA, GO:0016607=IDA, GO:0000166=IEA, GO:0000381=IDA, GO:0005730=IDA, GO:0006915=IDA, GO:0005634=IDA, GO:0003729=IDA, GO:0003676=IEA} RNA splicing, apoptotic process, mRNA processing, regulation of alternative mRNA splicing, via spliceosome cytoplasm, nuclear speck, nucleolus, nucleus mRNA binding, nucleic acid binding, nucleotide binding, protein binding Human RBM26 UniProtKB UniProtKB {GO:0005515=PMID:17577209, GO:0006397=GO_REF:0000002, GO:0000166=GO_REF:0000002, GO:0010923=PMID:19389623, GO:0003723=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q5T8P6 RNA-binding protein 26 protein 20111103 {GO:0005515=IPI, GO:0006397=IEA, GO:0000166=IEA, GO:0010923=IDA, GO:0003723=IEA, GO:0008270=IEA, GO:0003676=IEA} mRNA processing, negative regulation of phosphatase activity RNA binding, nucleic acid binding, nucleotide binding, protein binding, zinc ion binding Human RBM27 HPA UniProtKB {GO:0006397=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0016607=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002} Q9P2N5 RNA-binding protein 27 protein 20110516 {GO:0006397=IEA, GO:0005737=IEA, GO:0016607=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA} mRNA processing cytoplasm, nuclear speck, nucleolus, nucleus RNA binding, nucleotide binding, zinc ion binding NOT Human RBM28 HPA UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0005794=GO_REF:0000052, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005681=GO_REF:0000037, GO:0003676=GO_REF:0000002} Q9NW13 RNA-binding protein 28 protein 20100326 {GO:0008380=IEA, GO:0006397=IEA, GO:0005794=IDA, GO:0000166=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005681=IEA, GO:0003676=IEA} RNA splicing, mRNA processing Golgi apparatus, nucleolus, spliceosomal complex RNA binding, nucleic acid binding, nucleotide binding Human RBM3 PINC UniProtKB {GO:0006396=PMID:8634703, GO:0003723=GO_REF:0000037, GO:0009409=GO_REF:0000019, GO:0015934=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0045727=GO_REF:0000024, GO:0006412=GO_REF:0000019, GO:0030425=GO_REF:0000024, GO:0006417=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0000166=GO_REF:0000002, GO:0035196=GO_REF:0000019, GO:0043023=GO_REF:0000019} P98179 Putative RNA-binding protein 3 protein 20030904 {GO:0006396=TAS, GO:0003723=IEA, GO:0009409=IEA, GO:0015934=ISS, GO:0005634=ISS, GO:0045727=ISS, GO:0006412=IEA, GO:0030425=ISS, GO:0006417=ISS, GO:0005737=ISS, GO:0000166=IEA, GO:0035196=IEA, GO:0043023=IEA} RNA processing, positive regulation of translation, production of miRNAs involved in gene silencing by miRNA, regulation of translation, response to cold, translation cytoplasm, dendrite, large ribosomal subunit, nucleus RNA binding, nucleotide binding, ribosomal large subunit binding Human RBM33 UniProtKB UniProtKB {GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0003676=GO_REF:0000002} Q96EV2 RNA-binding protein 33 protein 20130413 {GO:0000166=IEA, GO:0003723=IEA, GO:0003676=IEA} RNA binding, nucleic acid binding, nucleotide binding Human UniProtKB-KW:KW-0694 RBM34 HPA UniProtKB {GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002} Q5TCT4 RNA-binding protein 34 protein 20101115 {GO:0000166=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA} nucleolus, nucleus RNA binding, nucleic acid binding, nucleotide binding Human RBM38 UniProtKB UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0007049=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0010830=GO_REF:0000019, GO:0043484=PMID:19285943, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002, GO:0003729=GO_REF:0000019, GO:0030154=GO_REF:0000037, GO:0005829=GO_REF:0000039} Q9H0Z9 RNA-binding protein 38 protein 20090325 {GO:0008380=IEA, GO:0006397=IEA, GO:0007049=IEA, GO:0000166=IEA, GO:0010830=IEA, GO:0043484=IDA, GO:0005634=IEA, GO:0003676=IEA, GO:0003729=IEA, GO:0030154=IEA, GO:0005829=IEA} RNA splicing, cell cycle, cell differentiation, mRNA processing, regulation of RNA splicing, regulation of myotube differentiation cytosol, nucleus mRNA binding, nucleic acid binding, nucleotide binding Human RBM39 InterPro UniProtKB {GO:0006397=GO_REF:0000002, GO:0008380=GO_REF:0000037, GO:0005515=PMID:15798186, GO:0006396=PMID:8227358, GO:0005813=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0003723=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0016607=GO_REF:0000039, GO:0015630=GO_REF:0000052, GO:0005654=PMID:8227358} Q5QP23 RNA-binding protein 39 protein 20130413 {GO:0006397=IEA, GO:0008380=IEA, GO:0005515=IPI, GO:0006396=TAS, GO:0005813=IDA, GO:0006355=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IEA, GO:0003676=IEA, GO:0006351=IEA, GO:0000166=IEA, GO:0016607=IEA, GO:0015630=IDA, GO:0005654=TAS} RNA processing, RNA splicing, mRNA processing, regulation of transcription, DNA-dependent, transcription, DNA-dependent centrosome, microtubule cytoskeleton, nuclear speck, nucleolus, nucleoplasm, nucleus RNA binding, nucleic acid binding, nucleotide binding, protein binding Human InterPro:IPR006509 RBM4 UniProtKB UniProtKB {GO:0008380=GO_REF:0000037, GO:0017148=PMID:17284590, GO:0005515=PMID:16934801, GO:0032055=PMID:17284590, GO:0010494=PMID:17284590, GO:0003723=PMID:19561594, GO:0005634=PMID:17284590, GO:0003729=PMID:21518792, GO:0051403=PMID:17284590, GO:0030154=GO_REF:0000037, GO:0005737=PMID:12628928, GO:0000166=GO_REF:0000002, GO:0000381=PMID:12628928, GO:0045947=PMID:19801630, GO:0097158=PMID:16260624, GO:0003730=GO_REF:0000024, GO:0097157=PMID:16260624, GO:0043153=GO_REF:0000024, GO:0046822=PMID:12628928, GO:0006397=GO_REF:0000037, GO:0006396=PMID:9169144, GO:0005730=PMID:12628928, GO:0033554=PMID:17284590, GO:0003676=GO_REF:0000002, GO:0002192=PMID:17284590, GO:0035278=PMID:19801630, GO:0002190=PMID:17284590, GO:0051149=PMID:21518792, GO:0035198=PMID:19801630, GO:0016607=PMID:12628928, GO:0005654=PMID:12628928, GO:0008270=GO_REF:0000002, GO:0097167=GO_REF:0000024} Q9BWF3 RNA-binding protein 4 protein 20110616 {GO:0008380=IEA, GO:0017148=IDA, GO:0005515=IPI, GO:0032055=IDA, GO:0010494=IDA, GO:0003723=IDA, GO:0005634=IDA, GO:0003729=IDA, GO:0051403=IDA, GO:0030154=IEA, GO:0005737=IDA, GO:0000166=IEA, GO:0000381=IDA, GO:0045947=IDA, GO:0097158=IDA, GO:0003730=ISS, GO:0097157=IDA, GO:0043153=ISS, GO:0046822=IDA, GO:0006397=IEA, GO:0006396=TAS, GO:0005730=IDA, GO:0033554=IDA, GO:0003676=IEA, GO:0002192=IDA, GO:0035278=IDA, GO:0002190=IDA, GO:0051149=IDA, GO:0035198=IDA, GO:0016607=IDA, GO:0005654=IDA, GO:0008270=IEA, GO:0097167=ISS} IRES-dependent translational initiation, RNA processing, RNA splicing, cap-independent translational initiation, cell differentiation, cellular response to stress, circadian regulation of translation, entrainment of circadian clock by photoperiod, mRNA processing, negative regulation of translation, negative regulation of translation in response to stress, negative regulation of translation involved in gene silencing by miRNA, negative regulation of translational initiation, positive regulation of muscle cell differentiation, regulation of alternative mRNA splicing, via spliceosome, regulation of nucleocytoplasmic transport, stress-activated MAPK cascade cytoplasm, cytoplasmic stress granule, nuclear speck, nucleolus, nucleoplasm, nucleus RNA binding, mRNA 3'-UTR binding, mRNA binding, miRNA binding, nucleic acid binding, nucleotide binding, pre-mRNA intronic binding, pre-mRNA intronic pyrimidine-rich binding, protein binding, zinc ion binding Human UniProtKB:P19544 RBM41 UniProtKB UniProtKB {GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037} Q96IZ5 RNA-binding protein 41 protein 20130413 {GO:0000166=IEA, GO:0003723=IEA} RNA binding, nucleotide binding Human UniProtKB-KW:KW-0694 RBM42 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002} Q9BTD8 RNA-binding protein 42 protein 20130413 {GO:0005737=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0003676=IEA} cytoplasm, nucleus RNA binding, nucleic acid binding, nucleotide binding Human UniProtKB-SubCell:SL-0086 RBM43 UniProtKB UniProtKB {GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037} Q6ZSC3 RNA-binding protein 43 protein 20130413 {GO:0000166=IEA, GO:0003723=IEA} RNA binding, nucleotide binding Human UniProtKB-KW:KW-0694 RBM45 HPA UniProtKB {GO:0005737=PMID:12220514, GO:0000166=GO_REF:0000002, GO:0003723=PMID:12220514, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0030154=GO_REF:0000037, GO:0007399=GO_REF:0000024} Q8IUH3 RNA-binding protein 45 protein 20120912 {GO:0005737=IDA, GO:0000166=IEA, GO:0003723=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0030154=IEA, GO:0007399=ISS} cell differentiation, nervous system development cytoplasm, nucleus RNA binding, nucleic acid binding, nucleotide binding Human RBM47 InterPro UniProtKB {GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002} D6RFL5 RNA-binding protein 47 protein 20130413 {GO:0000166=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0003676=IEA} nucleus RNA binding, nucleic acid binding, nucleotide binding Human InterPro:IPR000504 RBM48 HPA UniProtKB {GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q5RL73 RNA-binding protein 48 protein 20090616 {GO:0000166=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA} nucleolus, nucleus RNA binding, nucleotide binding NOT Human RBM4B UniProtKB UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0010628=GO_REF:0000019, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0007623=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0043153=GO_REF:0000024, GO:0032922=GO_REF:0000024, GO:0006417=GO_REF:0000024} Q9BQ04 RNA-binding protein 4B protein 20110923 {GO:0008380=IEA, GO:0006397=IEA, GO:0010628=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0005730=IEA, GO:0007623=ISS, GO:0008270=IEA, GO:0003676=IEA, GO:0043153=ISS, GO:0032922=ISS, GO:0006417=ISS} RNA splicing, circadian regulation of gene expression, circadian rhythm, entrainment of circadian clock by photoperiod, mRNA processing, positive regulation of gene expression, regulation of translation nucleolus RNA binding, nucleic acid binding, nucleotide binding, zinc ion binding Human UniProtKB:Q8VE92 RBM5 HPA UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:18951082, GO:0010467=Reactome:REACT_71, GO:0006396=PMID:10352938, GO:0000245=PMID:18951082, GO:0008285=PMID:18951082, GO:0043065=PMID:18840686, GO:0003723=PMID:10352938, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0003729=PMID:18840686, GO:0003677=PMID:10352938, GO:0000166=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0000381=PMID:18840686, GO:0005654=Reactome:REACT_1935, GO:0008270=GO_REF:0000002, GO:0005681=PMID:18951082} P52756 RNA-binding protein 5 protein 20090616 {GO:0008380=TAS, GO:0005515=IPI, GO:0010467=TAS, GO:0006396=TAS, GO:0000245=IDA, GO:0008285=TAS, GO:0043065=IDA, GO:0003723=TAS, GO:0005730=IDA, GO:0006915=IEA, GO:0005634=IDA, GO:0003729=IDA, GO:0003677=TAS, GO:0000166=IEA, GO:0000398=TAS, GO:0000381=IDA, GO:0005654=TAS, GO:0008270=IEA, GO:0005681=TAS} RNA processing, RNA splicing, apoptotic process, gene expression, mRNA splicing, via spliceosome, negative regulation of cell proliferation, positive regulation of apoptotic process, regulation of alternative mRNA splicing, via spliceosome, spliceosomal complex assembly nucleolus, nucleoplasm, nucleus, spliceosomal complex DNA binding, RNA binding, mRNA binding, nucleotide binding, protein binding, zinc ion binding NOT Human RBM6 PINC UniProtKB {GO:0006396=PMID:10352938, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002, GO:0003677=PMID:10352938} P78332 RNA-binding protein 6 protein 20030904 {GO:0006396=TAS, GO:0000166=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0003676=IEA, GO:0003677=TAS} RNA processing nucleus DNA binding, RNA binding, nucleic acid binding, nucleotide binding Human RBM7 UniProtKB UniProtKB {GO:0007126=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0003676=GO_REF:0000002} Q9Y580 RNA-binding protein 7 protein 20130413 {GO:0007126=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0003676=IEA} meiosis RNA binding, nucleic acid binding, nucleotide binding Human UniProtKB-KW:KW-0469 RBM8A HPA UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:23084401, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0016070=Reactome:REACT_21257, GO:0006366=Reactome:REACT_1366, GO:0016071=Reactome:REACT_20605, GO:0003723=PMID:11013075, GO:0005730=GO_REF:0000052, GO:0031124=Reactome:REACT_1849, GO:0005634=GO_REF:0000052, GO:0003729=PMID:11030346, GO:0071013=PMID:11991638, GO:0006417=GO_REF:0000037, GO:0005829=Reactome:REACT_75910, GO:0005737=PMID:11030346, GO:0006406=Reactome:REACT_1597, GO:0000184=Reactome:REACT_75886, GO:0000166=GO_REF:0000002, GO:0016607=GO_REF:0000039, GO:0000398=Reactome:REACT_467, GO:0005654=Reactome:REACT_2104, GO:0035145=PMID:16601204} Q9Y5S9 RNA-binding protein 8A protein 20090616 {GO:0008380=TAS, GO:0005515=IPI, GO:0010467=TAS, GO:0006369=TAS, GO:0016070=TAS, GO:0006366=TAS, GO:0016071=TAS, GO:0003723=NAS, GO:0005730=IDA, GO:0031124=TAS, GO:0005634=IDA, GO:0003729=NAS, GO:0071013=IDA, GO:0006417=IEA, GO:0005829=TAS, GO:0005737=NAS, GO:0006406=TAS, GO:0000184=TAS, GO:0000166=IEA, GO:0016607=IEA, GO:0000398=TAS, GO:0005654=TAS, GO:0035145=IDA} RNA metabolic process, RNA splicing, gene expression, mRNA 3'-end processing, mRNA export from nucleus, mRNA metabolic process, mRNA splicing, via spliceosome, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, regulation of translation, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter catalytic step 2 spliceosome, cytoplasm, cytosol, exon-exon junction complex, nuclear speck, nucleolus, nucleoplasm, nucleus RNA binding, mRNA binding, nucleotide binding, protein binding NOT Human RBMS1 PINC UniProtKB {GO:0006260=PMID:7838710, GO:0006396=PMID:8041632, GO:0003690=PMID:7838710, GO:0003697=PMID:7838710, GO:0000166=GO_REF:0000002, GO:0003723=PMID:8041632, GO:0005634=PMID:7838710, GO:0003676=GO_REF:0000002} P29558 RNA-binding motif, single-stranded-interacting protein 1 protein 20030904 {GO:0006260=NAS, GO:0006396=TAS, GO:0003690=NAS, GO:0003697=NAS, GO:0000166=IEA, GO:0003723=NAS, GO:0005634=NAS, GO:0003676=IEA} DNA replication, RNA processing nucleus RNA binding, double-stranded DNA binding, nucleic acid binding, nucleotide binding, single-stranded DNA binding Human RBMS2 PINC UniProtKB {GO:0006396=PMID:8041632, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002} Q15434 RNA-binding motif, single-stranded-interacting protein 2 protein 20030904 {GO:0006396=TAS, GO:0000166=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0003676=IEA} RNA processing nucleus RNA binding, nucleic acid binding, nucleotide binding Human RBMX IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0048026=GO_REF:0000024, GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0048025=GO_REF:0000024, GO:0006366=PMID:21327109, GO:0003723=PMID:21327109, GO:0005634=PMID:19282290, GO:0071013=PMID:11991638, GO:0003729=PMID:12165565, GO:0044530=PMID:19282290, GO:0000166=GO_REF:0000002, GO:0000381=PMID:12165565, GO:0045944=PMID:18541147, GO:0051260=GO_REF:0000024, GO:0006509=PMID:18445477, GO:0070062=PMID:18445477, GO:0005719=PMID:21327109, GO:0001047=PMID:18541147, GO:0003676=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0003682=PMID:18541147, GO:0030529=GO_REF:0000038, GO:0071347=PMID:18445477, GO:0005654=Reactome:REACT_1935} P38159 RNA-binding motif protein, X chromosome protein 20130415 {GO:0005515=IPI, GO:0048026=ISS, GO:0008380=TAS, GO:0010467=TAS, GO:0048025=ISS, GO:0006366=IDA, GO:0003723=IDA, GO:0005634=IDA, GO:0071013=IDA, GO:0003729=IDA, GO:0044530=IDA, GO:0000166=IEA, GO:0000381=IDA, GO:0045944=IDA, GO:0051260=ISS, GO:0006509=IDA, GO:0070062=IDA, GO:0005719=IDA, GO:0001047=IDA, GO:0003676=IEA, GO:0000398=TAS, GO:0003682=IDA, GO:0030529=IEA, GO:0071347=IDA, GO:0005654=TAS} RNA splicing, cellular response to interleukin-1, gene expression, mRNA splicing, via spliceosome, membrane protein ectodomain proteolysis, negative regulation of mRNA splicing, via spliceosome, positive regulation of mRNA splicing, via spliceosome, positive regulation of transcription from RNA polymerase II promoter, protein homooligomerization, regulation of alternative mRNA splicing, via spliceosome, transcription from RNA polymerase II promoter catalytic step 2 spliceosome, extracellular vesicular exosome, nuclear euchromatin, nucleoplasm, nucleus, ribonucleoprotein complex, supraspliceosomal complex RNA binding, chromatin binding, core promoter binding, mRNA binding, nucleic acid binding, nucleotide binding, protein binding Human UniProtKB:Q5VWX1 RBMX2 UniProtKB UniProtKB {GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037} Q9Y388 RNA-binding motif protein, X-linked 2 protein 20130413 {GO:0000166=IEA, GO:0003723=IEA} RNA binding, nucleotide binding Human UniProtKB-KW:KW-0694 RBMXL1 UniProtKB UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0030529=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039} Q96E39 RNA binding motif protein, X-linked-like-1 protein 20130413 {GO:0008380=IEA, GO:0006397=IEA, GO:0000166=IEA, GO:0030529=IEA, GO:0003723=IEA, GO:0005634=IEA} RNA splicing, mRNA processing nucleus, ribonucleoprotein complex RNA binding, nucleotide binding Human UniProtKB-SubCell:SL-0191 RBMXL2 HPA UniProtKB {GO:0000166=GO_REF:0000002, GO:0030529=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} O75526 RNA-binding motif protein, X-linked-like-2 protein 20110516 {GO:0000166=IEA, GO:0030529=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA} nucleolus, nucleus, ribonucleoprotein complex RNA binding, nucleotide binding NOT Human RBMXL3 UniProtKB UniProtKB {GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037} Q8N7X1 RNA-binding motif protein, X-linked-like-3 protein 20130413 {GO:0000166=IEA, GO:0003723=IEA} RNA binding, nucleotide binding Human UniProtKB-KW:KW-0694 RBMY1A1 UniProtKB UniProtKB {GO:0005515=PMID:12165565, GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0000381=PMID:12165565, GO:0005634=GO_REF:0000039, GO:0003729=PMID:12165565, GO:0003676=GO_REF:0000002} P0DJD3 RNA-binding motif protein, Y chromosome, family 1 member A1 protein 20120805 {GO:0005515=IPI, GO:0008380=IEA, GO:0006397=IEA, GO:0000166=IEA, GO:0000381=IDA, GO:0005634=IEA, GO:0003729=IDA, GO:0003676=IEA} RNA splicing, mRNA processing, regulation of alternative mRNA splicing, via spliceosome nucleus mRNA binding, nucleic acid binding, nucleotide binding, protein binding Human UniProtKB:P62995 RBP1 Reactome UniProtKB {GO:0005215=GO_REF:0000002, GO:0007603=Reactome:REACT_160125, GO:0033189=GO_REF:0000019, GO:0016918=GO_REF:0000037, GO:0019841=GO_REF:0000019, GO:0001523=Reactome:REACT_160156, GO:0044297=GO_REF:0000019, GO:0008289=GO_REF:0000002, GO:0005829=Reactome:REACT_160295, GO:0006776=PMID:3472205, GO:0042572=GO_REF:0000019, GO:0030852=GO_REF:0000019, GO:0005501=PMID:3472205, GO:0002138=GO_REF:0000019} P09455 Retinol-binding protein 1 protein 20120809 {GO:0005215=IEA, GO:0007603=TAS, GO:0033189=IEA, GO:0016918=IEA, GO:0019841=IEA, GO:0001523=TAS, GO:0044297=IEA, GO:0008289=IEA, GO:0005829=TAS, GO:0006776=TAS, GO:0042572=IEA, GO:0030852=IEA, GO:0005501=TAS, GO:0002138=IEA} phototransduction, visible light, regulation of granulocyte differentiation, response to vitamin A, retinoic acid biosynthetic process, retinoid metabolic process, retinol metabolic process, vitamin A metabolic process cell body, cytosol lipid binding, retinal binding, retinoid binding, retinol binding, transporter activity Human RBP2 HPA UniProtKB {GO:0005215=GO_REF:0000002, GO:0005794=GO_REF:0000052, GO:0007603=Reactome:REACT_160125, GO:0008544=PMID:1654334, GO:0006776=PMID:2992469, GO:0005501=PMID:7657783, GO:0016918=GO_REF:0000037, GO:0001523=Reactome:REACT_24968, GO:0019841=GO_REF:0000019, GO:0005829=Reactome:REACT_160311} P50120 Retinol-binding protein 2 protein 20110516 {GO:0005215=IEA, GO:0005794=IDA, GO:0007603=TAS, GO:0008544=TAS, GO:0006776=TAS, GO:0005501=TAS, GO:0016918=IEA, GO:0001523=TAS, GO:0019841=IEA, GO:0005829=TAS} epidermis development, phototransduction, visible light, retinoid metabolic process, vitamin A metabolic process Golgi apparatus, cytosol retinal binding, retinoid binding, retinol binding, transporter activity Human RBP3 Reactome UniProtKB {GO:0006629=PMID:2542268, GO:0007603=Reactome:REACT_160125, GO:0033165=GO_REF:0000039, GO:0005501=PMID:2542268, GO:0016918=GO_REF:0000037, GO:0006810=GO_REF:0000037, GO:0006508=GO_REF:0000002, GO:0008236=GO_REF:0000002, GO:0005576=Reactome:REACT_160302, GO:0001523=Reactome:REACT_160156, GO:0007601=PMID:2542268} P10745 Retinol-binding protein 3 protein 20130301 {GO:0006629=TAS, GO:0007603=TAS, GO:0033165=IEA, GO:0005501=TAS, GO:0016918=IEA, GO:0006810=IEA, GO:0006508=IEA, GO:0008236=IEA, GO:0005576=TAS, GO:0001523=TAS, GO:0007601=TAS} lipid metabolic process, phototransduction, visible light, proteolysis, retinoid metabolic process, transport, visual perception extracellular region, interphotoreceptor matrix retinal binding, retinoid binding, serine-type peptidase activity Human RBP4 UniProtKB UniProtKB {GO:0005515=PMID:986177, GO:0005215=GO_REF:0000002, GO:0060044=GO_REF:0000024, GO:0060065=GO_REF:0000024, GO:0007603=Reactome:REACT_160125, GO:0030324=GO_REF:0000024, GO:0045471=GO_REF:0000019, GO:0001654=PMID:10232633, GO:0060068=GO_REF:0000024, GO:0006094=PMID:18466349, GO:0016918=GO_REF:0000037, GO:0048706=GO_REF:0000024, GO:0007283=GO_REF:0000019, GO:0019841=PMID:571335, GO:0005615=PMID:17003346, GO:0005829=Reactome:REACT_160296, GO:0007507=GO_REF:0000024, GO:0030277=PMID:10944490, GO:0050908=GO_REF:0000019, GO:0042574=GO_REF:0000019, GO:0042572=PMID:10232633, GO:0005501=GO_REF:0000002, GO:0048807=GO_REF:0000024, GO:0032024=PMID:16034410, GO:0032526=PMID:571335, GO:0032868=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0036094=GO_REF:0000002, GO:0005576=GO_REF:0000038, GO:0042593=PMID:17003346, GO:0060059=GO_REF:0000024, GO:0001523=Reactome:REACT_160156, GO:0048562=GO_REF:0000024, GO:0060347=GO_REF:0000024, GO:0048738=GO_REF:0000024, GO:0034633=PMID:571335, GO:0034632=PMID:571335, GO:0043234=GO_REF:0000019, GO:0051024=GO_REF:0000024, GO:0060157=GO_REF:0000024, GO:0008584=GO_REF:0000019} Q5VY30 Plasma retinol-binding protein(1-182) protein 20130413 {GO:0005515=IPI, GO:0005215=IEA, GO:0060044=ISS, GO:0060065=ISS, GO:0007603=TAS, GO:0030324=ISS, GO:0045471=IEA, GO:0001654=IMP, GO:0060068=ISS, GO:0006094=IMP, GO:0016918=IEA, GO:0048706=ISS, GO:0007283=IEA, GO:0019841=IDA, GO:0005615=IDA, GO:0005829=TAS, GO:0007507=ISS, GO:0030277=IDA, GO:0050908=IEA, GO:0042574=IEA, GO:0042572=IMP, GO:0005501=IEA, GO:0048807=ISS, GO:0032024=IMP, GO:0032526=IDA, GO:0032868=IEA, GO:0046982=IEA, GO:0036094=IEA, GO:0005576=IEA, GO:0042593=IDA, GO:0060059=ISS, GO:0001523=TAS, GO:0048562=ISS, GO:0060347=ISS, GO:0048738=ISS, GO:0034633=IC, GO:0034632=IC, GO:0043234=IEA, GO:0051024=ISS, GO:0060157=ISS, GO:0008584=IEA} cardiac muscle tissue development, detection of light stimulus involved in visual perception, embryonic organ morphogenesis, embryonic retina morphogenesis in camera-type eye, embryonic skeletal system development, eye development, female genitalia morphogenesis, gluconeogenesis, glucose homeostasis, heart development, heart trabecula formation, lung development, maintenance of gastrointestinal epithelium, male gonad development, negative regulation of cardiac muscle cell proliferation, phototransduction, visible light, positive regulation of immunoglobulin secretion, positive regulation of insulin secretion, response to ethanol, response to insulin stimulus, response to retinoic acid, retinal metabolic process, retinoid metabolic process, retinol metabolic process, retinol transport, spermatogenesis, urinary bladder development, uterus development, vagina development cytosol, extracellular region, extracellular space, protein complex protein binding, protein heterodimerization activity, retinal binding, retinoid binding, retinol binding, retinol transporter activity, small molecule binding, transporter activity Human UniProtKB-KW:KW-0964 RBP5 UniProtKB UniProtKB {GO:0005215=GO_REF:0000002, GO:0005737=GO_REF:0000029, GO:0006810=GO_REF:0000029, GO:0005501=PMID:11274389, GO:0016918=GO_REF:0000037, GO:0019841=GO_REF:0000037} P82980 Retinol-binding protein 5 protein 20021104 {GO:0005215=IEA, GO:0005737=NAS, GO:0006810=NAS, GO:0005501=TAS, GO:0016918=IEA, GO:0019841=IEA} transport cytoplasm retinal binding, retinoid binding, retinol binding, transporter activity Human RBPJ BHF-UCL UniProtKB {GO:0060045=GO_REF:0000024, GO:0005515=PMID:10713164, GO:0010467=Reactome:REACT_71, GO:0003160=GO_REF:0000024, GO:0035912=GO_REF:0000024, GO:0003700=PMID:9874765, GO:0006367=Reactome:REACT_14835, GO:0000982=GO_REF:0000002, GO:0000150=PMID:8406481, GO:0005634=PMID:21102556, GO:0003214=GO_REF:0000024, GO:0001837=GO_REF:0000024, GO:0007221=PMID:21102556, GO:1901189=GO_REF:0000024, GO:0030513=GO_REF:0000024, GO:0005737=PMID:21102556, GO:0030279=GO_REF:0000024, GO:0061314=PMID:21311046, GO:1901186=GO_REF:0000024, GO:0007219=PMID:18663143, GO:0045944=PMID:18663143, GO:0003222=GO_REF:0000024, GO:0060716=GO_REF:0000024, GO:0001103=PMID:16287852, GO:0003198=GO_REF:0000024, GO:0005730=PMID:9874765, GO:0006310=PMID:8406481, GO:0000122=GO_REF:0000024, GO:0072554=GO_REF:0000024, GO:0001525=GO_REF:0000024, GO:0000978=GO_REF:0000002, GO:0003677=PMID:9874765, GO:0036302=GO_REF:0000024, GO:0003151=GO_REF:0000024, GO:2000138=GO_REF:0000024, GO:0002193=PMID:16510869, GO:0001077=PMID:18663143, GO:0097101=GO_REF:0000024, GO:0005654=Reactome:REACT_160309, GO:0045892=PMID:10713164, GO:0003256=GO_REF:0000024} Q06330 Recombining binding protein suppressor of hairless protein 20120920 {GO:0060045=ISS, GO:0005515=IPI, GO:0010467=TAS, GO:0003160=ISS, GO:0035912=ISS, GO:0003700=TAS, GO:0006367=TAS, GO:0000982=IEA, GO:0000150=NAS, GO:0005634=IDA, GO:0003214=ISS, GO:0001837=ISS, GO:0007221=IDA, GO:1901189=ISS, GO:0030513=ISS, GO:0005737=IDA, GO:0030279=ISS, GO:0061314=IC, GO:1901186=ISS, GO:0007219=IMP, GO:0045944=IMP, GO:0003222=ISS, GO:0060716=ISS, GO:0001103=IPI, GO:0003198=ISS, GO:0005730=IDA, GO:0006310=NAS, GO:0000122=ISS, GO:0072554=ISS, GO:0001525=ISS, GO:0000978=IEA, GO:0003677=TAS, GO:0036302=ISS, GO:0003151=ISS, GO:2000138=ISS, GO:0002193=IDA, GO:0001077=IDA, GO:0097101=ISS, GO:0005654=TAS, GO:0045892=IDA, GO:0003256=ISS} DNA recombination, Notch signaling involved in heart development, Notch signaling pathway, angiogenesis, atrioventricular canal development, blood vessel endothelial cell fate specification, blood vessel lumenization, cardiac left ventricle morphogenesis, dorsal aorta morphogenesis, endocardium morphogenesis, epithelial to mesenchymal transition, epithelial to mesenchymal transition involved in endocardial cushion formation, gene expression, labyrinthine layer blood vessel development, negative regulation of ossification, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, outflow tract morphogenesis, positive regulation of BMP signaling pathway, positive regulation of ERBB signaling pathway, positive regulation of cardiac muscle cell proliferation, positive regulation of cell proliferation involved in heart morphogenesis, positive regulation of ephrin receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription of Notch receptor target, regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation, transcription initiation from RNA polymerase II promoter, ventricular trabecula myocardium morphogenesis MAML1-RBP-Jkappa- ICN1 complex, cytoplasm, nucleolus, nucleoplasm, nucleus DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II repressing transcription factor binding, protein binding, recombinase activity, sequence-specific DNA binding transcription factor activity Human UniProtKB:P31266 RBPJL PINC UniProtKB {GO:0007165=PMID:9929984, GO:0005667=GO_REF:0000019, GO:0003700=PMID:9929984, GO:0000982=GO_REF:0000002, GO:0005634=GO_REF:0000002, GO:0045893=GO_REF:0000019, GO:0000978=GO_REF:0000002} Q9UBG7 Recombining binding protein suppressor of hairless-like protein protein 20050308 {GO:0007165=TAS, GO:0005667=IEA, GO:0003700=TAS, GO:0000982=IEA, GO:0005634=IEA, GO:0045893=IEA, GO:0000978=IEA} positive regulation of transcription, DNA-dependent, signal transduction nucleus, transcription factor complex RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, sequence-specific DNA binding transcription factor activity Human RBPMS IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0006396=PMID:8855282, GO:0005737=GO_REF:0000039, GO:0006355=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0008143=PMID:17099224, GO:0003713=PMID:17099224, GO:0010862=PMID:17099224, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002, GO:0060391=PMID:17099224, GO:0006351=GO_REF:0000037} Q93062 RNA-binding protein with multiple splicing protein 20130415 {GO:0005515=IPI, GO:0006396=TAS, GO:0005737=IEA, GO:0006355=IEA, GO:0000166=IEA, GO:0008143=IDA, GO:0003713=IDA, GO:0010862=IDA, GO:0005634=IEA, GO:0003676=IEA, GO:0060391=IDA, GO:0006351=IEA} RNA processing, positive regulation of SMAD protein import into nucleus, positive regulation of pathway-restricted SMAD protein phosphorylation, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus nucleic acid binding, nucleotide binding, poly(A) RNA binding, protein binding, transcription coactivator activity Human UniProtKB:Q96PU8 RBPMS2 InterPro UniProtKB {GO:0000166=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q6ZRY4 RNA-binding protein with multiple splicing 2 protein 20130413 {GO:0000166=IEA, GO:0003676=IEA} nucleic acid binding, nucleotide binding Human InterPro:IPR000504 RBX1 IntAct UniProtKB {GO:0005515=PMID:18805092, GO:0031461=PMID:22405651, GO:0004842=PMID:22405651, GO:0016567=PMID:20389280, GO:0006513=PMID:22358839, GO:0030891=GO_REF:0000019, GO:0061418=Reactome:REACT_120815, GO:0031146=GO_REF:0000024, GO:0032403=GO_REF:0000019, GO:0005829=Reactome:REACT_121002, GO:0007219=Reactome:REACT_118859, GO:0019788=PMID:19250909, GO:0016032=Reactome:REACT_6185, GO:0031625=PMID:17636018, GO:0045116=PMID:19250909, GO:0071456=Reactome:REACT_121311, GO:0033554=Reactome:REACT_120956, GO:0006281=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0031463=PMID:22358839, GO:0031462=PMID:17636018, GO:0008270=GO_REF:0000002, GO:0043161=PMID:20389280, GO:0031465=PMID:18794347, GO:0005654=Reactome:REACT_160209, GO:0031464=PMID:20223979, GO:0031466=PMID:17636018, GO:0019005=PMID:23263282} P62877 E3 ubiquitin-protein ligase RBX1 protein 20130415 {GO:0005515=IPI, GO:0031461=IDA, GO:0004842=IDA, GO:0016567=IDA, GO:0006513=IDA, GO:0030891=IEA, GO:0061418=TAS, GO:0031146=ISS, GO:0032403=IEA, GO:0005829=TAS, GO:0007219=TAS, GO:0019788=IDA, GO:0016032=TAS, GO:0031625=IDA, GO:0045116=IDA, GO:0071456=TAS, GO:0033554=TAS, GO:0006281=IEA, GO:0019048=IEA, GO:0031463=IDA, GO:0031462=IDA, GO:0008270=IEA, GO:0043161=IDA, GO:0031465=IDA, GO:0005654=TAS, GO:0031464=IDA, GO:0031466=IDA, GO:0019005=IDA} DNA repair, Notch signaling pathway, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, cellular response to hypoxia, cellular response to stress, proteasomal ubiquitin-dependent protein catabolic process, protein monoubiquitination, protein neddylation, protein ubiquitination, regulation of transcription from RNA polymerase II promoter in response to hypoxia, viral reproduction, virus-host interaction Cul2-RING ubiquitin ligase complex, Cul3-RING ubiquitin ligase complex, Cul4A-RING ubiquitin ligase complex, Cul4B-RING ubiquitin ligase complex, Cul5-RING ubiquitin ligase complex, SCF ubiquitin ligase complex, VCB complex, cullin-RING ubiquitin ligase complex, cytosol, nucleoplasm NEDD8 ligase activity, protein binding, protein complex binding, ubiquitin protein ligase binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q93034 RC3H1 BHF-UCL UniProtKB {GO:0043488=GO_REF:0000024, GO:0004842=PMID:19217324, GO:0033962=GO_REF:0000024, GO:0010494=GO_REF:0000024, GO:0050856=GO_REF:0000024, GO:0046007=GO_REF:0000024, GO:0000956=GO_REF:0000024, GO:0030889=GO_REF:0000024, GO:0010608=GO_REF:0000024, GO:0000932=GO_REF:0000024, GO:0002635=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0045623=GO_REF:0000024, GO:0003730=GO_REF:0000024, GO:0002634=GO_REF:0000024} Q5TC82 Probable E3 ubiquitin-protein ligase Roquin protein 20110623 {GO:0043488=ISS, GO:0004842=TAS, GO:0033962=ISS, GO:0010494=ISS, GO:0050856=ISS, GO:0046007=ISS, GO:0000956=ISS, GO:0030889=ISS, GO:0010608=ISS, GO:0000932=ISS, GO:0002635=ISS, GO:0008270=IEA, GO:0045623=ISS, GO:0003730=ISS, GO:0002634=ISS} cytoplasmic mRNA processing body assembly, negative regulation of B cell proliferation, negative regulation of T-helper cell differentiation, negative regulation of activated T cell proliferation, negative regulation of germinal center formation, nuclear-transcribed mRNA catabolic process, posttranscriptional regulation of gene expression, regulation of T cell receptor signaling pathway, regulation of germinal center formation, regulation of mRNA stability cytoplasmic mRNA processing body, cytoplasmic stress granule mRNA 3'-UTR binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q4VGL6 RC3H2 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0048471=GO_REF:0000039, GO:0016020=PMID:10938276, GO:0009986=PMID:10938276, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=PMID:10938276, GO:0012505=GO_REF:0000039} Q9HBD1 RING finger and CCCH-type zinc finger domain-containing protein 2 protein 20031216 {GO:0008150=ND, GO:0048471=IEA, GO:0016020=IDA, GO:0009986=IDA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IDA, GO:0012505=IEA} biological_process cell surface, endomembrane system, membrane, perinuclear region of cytoplasm DNA binding, nucleic acid binding, zinc ion binding Human RCAN1 GOC UniProtKB {GO:0006355=PMID:8595418, GO:0043627=GO_REF:0000019, GO:0019722=GO_REF:0000002, GO:0003700=PMID:8595418, GO:0051151=GO_REF:0000019, GO:0008015=PMID:8595418, GO:0048741=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0007417=PMID:8595418, GO:0003677=PMID:8595418, GO:0009612=GO_REF:0000019, GO:0007165=PMID:8595418, GO:0005737=GO_REF:0000019, GO:0043666=GO_REF:0000019} P53805 Calcipressin-1 protein 20130413 {GO:0006355=TAS, GO:0043627=IEA, GO:0019722=IEA, GO:0003700=TAS, GO:0051151=IEA, GO:0008015=TAS, GO:0048741=IEA, GO:0005634=IEA, GO:0007417=TAS, GO:0003677=TAS, GO:0009612=IEA, GO:0007165=TAS, GO:0005737=IEA, GO:0043666=IEA} blood circulation, calcium-mediated signaling, central nervous system development, negative regulation of smooth muscle cell differentiation, regulation of phosphoprotein phosphatase activity, regulation of transcription, DNA-dependent, response to estrogen stimulus, response to mechanical stimulus, signal transduction, skeletal muscle fiber development cytoplasm, nucleus DNA binding, sequence-specific DNA binding transcription factor activity Human RCAN2 UniProtKB UniProtKB {GO:0030346=GO_REF:0000029, GO:0019722=GO_REF:0000002, GO:0000166=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0007417=GO_REF:0000029} Q14206 Calcipressin-2 protein 20061026 {GO:0030346=NAS, GO:0019722=IEA, GO:0000166=IEA, GO:0005575=ND, GO:0007417=NAS} calcium-mediated signaling, central nervous system development cellular_component nucleotide binding, protein phosphatase 2B binding Human RCAN3 PINC UniProtKB {GO:0031013=PMID:16516408, GO:0019722=GO_REF:0000002, GO:0003723=PMID:10756093, GO:0009653=PMID:10756093} Q9UKA8 Calcipressin-3 protein 20031119 {GO:0031013=IPI, GO:0019722=IEA, GO:0003723=TAS, GO:0009653=TAS} anatomical structure morphogenesis, calcium-mediated signaling RNA binding, troponin I binding Human RCBTB1 LIFEdb UniProtKB {GO:0005737=GO_REF:0000054, GO:0007049=GO_REF:0000037, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q8NDN9 RCC1 and BTB domain-containing protein 1 protein 20100607 {GO:0005737=IDA, GO:0007049=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0006351=IEA, GO:0016568=IEA} cell cycle, chromatin modification, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus Human RCBTB2 PINC UniProtKB {GO:0005087=PMID:9806834} O95199 RCC1 and BTB domain-containing protein 2 protein 20030904 {GO:0005087=TAS} Ran guanyl-nucleotide exchange factor activity Human RCC1 HPA UniProtKB {GO:0005515=PMID:18617507, GO:0022415=Reactome:REACT_6361, GO:0031965=GO_REF:0000052, GO:0000790=PMID:15014043, GO:0007088=PMID:15014043, GO:0000794=PMID:15014043, GO:0031492=PMID:17435751, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0051225=PMID:17435751, GO:0042393=PMID:11375490, GO:0000082=PMID:3678831, GO:0005737=PMID:17435751, GO:0007067=GO_REF:0000037, GO:0007059=PMID:17435751, GO:0003682=PMID:2677018, GO:0016032=Reactome:REACT_6256, GO:0005654=Reactome:REACT_9507, GO:0007052=PMID:15014043, GO:0005087=PMID:1944575, GO:0051301=GO_REF:0000037} P18754 Regulator of chromosome condensation protein 20101115 {GO:0005515=IPI, GO:0022415=TAS, GO:0031965=IDA, GO:0000790=IDA, GO:0007088=IDA, GO:0000794=IDA, GO:0031492=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0051225=IMP, GO:0042393=IDA, GO:0000082=IMP, GO:0005737=IDA, GO:0007067=IEA, GO:0007059=IMP, GO:0003682=IDA, GO:0016032=TAS, GO:0005654=TAS, GO:0007052=IDA, GO:0005087=IDA, GO:0051301=IEA} G1/S transition of mitotic cell cycle, cell division, chromosome segregation, mitosis, mitotic spindle organization, regulation of mitosis, spindle assembly, viral reproduction, viral reproductive process condensed nuclear chromosome, cytoplasm, nuclear chromatin, nuclear membrane, nucleolus, nucleoplasm, nucleus Ran guanyl-nucleotide exchange factor activity, chromatin binding, histone binding, nucleosomal DNA binding, protein binding Human RCC2 Reactome UniProtKB {GO:0000236=Reactome:REACT_682, GO:0000087=Reactome:REACT_910, GO:0005874=GO_REF:0000037, GO:0005819=GO_REF:0000039, GO:0005730=GO_REF:0000039, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0000775=GO_REF:0000039, GO:0005829=Reactome:REACT_150414, GO:0051301=GO_REF:0000037} Q9P258 Protein RCC2 protein 20130213 {GO:0000236=TAS, GO:0000087=TAS, GO:0005874=IEA, GO:0005819=IEA, GO:0005730=IEA, GO:0000278=TAS, GO:0000090=TAS, GO:0000775=IEA, GO:0005829=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, cell division, mitotic anaphase, mitotic cell cycle, mitotic prometaphase chromosome, centromeric region, cytosol, microtubule, nucleolus, spindle Human RCCD1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052} G3V2I3 RCC1 domain-containing protein 1 protein 20110516 {GO:0005737=IDA, GO:0005886=IDA} cytoplasm, plasma membrane Human RCE1 PINC UniProtKB {GO:0004197=PMID:19188362, GO:0016020=GO_REF:0000002, GO:0005887=PMID:10085068, GO:0006508=PMID:10085068, GO:0005789=PMID:19188362, GO:0071586=PMID:19188362, GO:0004222=PMID:10085068} Q9Y256 CAAX prenyl protease 2 protein 20030904 {GO:0004197=IDA, GO:0016020=IEA, GO:0005887=TAS, GO:0006508=TAS, GO:0005789=IDA, GO:0071586=IMP, GO:0004222=TAS} CAAX-box protein processing, proteolysis endoplasmic reticulum membrane, integral to plasma membrane, membrane cysteine-type endopeptidase activity, metalloendopeptidase activity Human RCHY1 HPA UniProtKB {GO:0005515=PMID:21988832, GO:0004842=PMID:19483087, GO:0016567=PMID:19043414, GO:0005102=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0032436=PMID:19483087, GO:0000151=PMID:19043414, GO:0005634=GO_REF:0000052, GO:0042803=PMID:19483087, GO:0002039=PMID:19043414, GO:0005737=GO_REF:0000052, GO:0016607=GO_REF:0000039, GO:0042787=PMID:19483087, GO:0031398=PMID:19483087, GO:0008270=PMID:19043414} Q96PM5 RING finger and CHY zinc finger domain-containing protein 1 protein 20101115 {GO:0005515=IPI, GO:0004842=IDA, GO:0016567=IDA, GO:0005102=IEA, GO:0005730=IDA, GO:0032436=IDA, GO:0000151=IDA, GO:0005634=IDA, GO:0042803=IPI, GO:0002039=IPI, GO:0005737=IDA, GO:0016607=IEA, GO:0042787=IDA, GO:0031398=IDA, GO:0008270=IDA} positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of protein ubiquitination, protein ubiquitination, protein ubiquitination involved in ubiquitin-dependent protein catabolic process cytoplasm, nuclear speck, nucleolus, nucleus, ubiquitin ligase complex p53 binding, protein binding, protein homodimerization activity, receptor binding, ubiquitin-protein ligase activity, zinc ion binding Human RCL1 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0006396=GO_REF:0000002, GO:0003963=PMID:10790377, GO:0042254=GO_REF:0000037, GO:0005730=GO_REF:0000029, GO:0003824=GO_REF:0000002} Q9Y2P8 RNA 3'-terminal phosphate cyclase-like protein protein 20061026 {GO:0008150=ND, GO:0006396=IEA, GO:0003963=NAS, GO:0042254=IEA, GO:0005730=NAS, GO:0003824=IEA} RNA processing, biological_process, ribosome biogenesis nucleolus RNA-3'-phosphate cyclase activity, catalytic activity Human RCN1 HPA UniProtKB {GO:0005515=PMID:16713569, GO:0005783=GO_REF:0000052, GO:0005509=GO_REF:0000002, GO:0005788=GO_REF:0000039, GO:0043010=GO_REF:0000019, GO:0001701=GO_REF:0000019} Q15293 Reticulocalbin-1 protein 20110516 {GO:0005515=IPI, GO:0005783=IDA, GO:0005509=IEA, GO:0005788=IEA, GO:0043010=IEA, GO:0001701=IEA} camera-type eye development, in utero embryonic development endoplasmic reticulum, endoplasmic reticulum lumen calcium ion binding, protein binding Human RCN2 PINC UniProtKB {GO:0005783=PMID:8034671, GO:0005509=GO_REF:0000002, GO:0005788=GO_REF:0000039} Q14257 Reticulocalbin-2 protein 20030904 {GO:0005783=TAS, GO:0005509=IEA, GO:0005788=IEA} endoplasmic reticulum, endoplasmic reticulum lumen calcium ion binding Human RCN3 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0005509=GO_REF:0000002, GO:0005788=GO_REF:0000039} Q96D15 Reticulocalbin-3 protein 20130415 {GO:0005515=IPI, GO:0005509=IEA, GO:0005788=IEA} endoplasmic reticulum lumen calcium ion binding, protein binding Human UniProtKB:Q9UMX1 RCOR1 IntAct UniProtKB {GO:0005515=PMID:21258344, GO:0070933=PMID:17555596, GO:0044212=PMID:17555596, GO:0005634=PMID:10734093, GO:0003677=GO_REF:0000002, GO:0001078=PMID:10449787, GO:0045654=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0003682=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0017053=PMID:10734093, GO:0030218=GO_REF:0000019, GO:0005654=Reactome:REACT_25101, GO:0045892=PMID:10449787} Q9UKL0 REST corepressor 1 protein 20130415 {GO:0005515=IPI, GO:0070933=IDA, GO:0044212=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0001078=IDA, GO:0045654=IEA, GO:0007596=TAS, GO:0003682=IEA, GO:0019048=IEA, GO:0017053=IDA, GO:0030218=IEA, GO:0005654=TAS, GO:0045892=IDA} blood coagulation, erythrocyte differentiation, histone H4 deacetylation, negative regulation of transcription, DNA-dependent, positive regulation of megakaryocyte differentiation, virus-host interaction nucleoplasm, nucleus, transcriptional repressor complex DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, chromatin binding, protein binding, transcription regulatory region DNA binding Human UniProtKB:O60341 RCOR2 ENSEMBL UniProtKB {GO:0005667=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0003714=GO_REF:0000019, GO:0003682=GO_REF:0000002, GO:0045892=GO_REF:0000019, GO:0000785=GO_REF:0000019, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q8IZ40 REST corepressor 2 protein 20130413 {GO:0005667=IEA, GO:0003700=IEA, GO:0003714=IEA, GO:0003682=IEA, GO:0045892=IEA, GO:0000785=IEA, GO:0003677=IEA, GO:0006351=IEA} negative regulation of transcription, DNA-dependent, transcription, DNA-dependent chromatin, transcription factor complex DNA binding, chromatin binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human Ensembl:ENSRNOP00000035978 RCOR3 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0006355=GO_REF:0000037, GO:0003682=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q9P2K3 REST corepressor 3 protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0003682=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, chromatin binding, protein binding Human UniProtKB:Q14687 RCVRN PINC UniProtKB {GO:0007165=PMID:1672047, GO:0005509=GO_REF:0000019, GO:0051924=GO_REF:0000019, GO:0007602=GO_REF:0000019, GO:0007601=GO_REF:0000019, GO:0008048=PMID:1672047} P35243 Recoverin protein 20030904 {GO:0007165=TAS, GO:0005509=IEA, GO:0051924=IEA, GO:0007602=IEA, GO:0007601=IEA, GO:0008048=TAS} phototransduction, regulation of calcium ion transport, signal transduction, visual perception calcium ion binding, calcium sensitive guanylate cyclase activator activity Human RD3 ENSEMBL UniProtKB {GO:0060041=GO_REF:0000019, GO:0007601=GO_REF:0000037, GO:0050896=GO_REF:0000037} Q7Z3Z2 Protein RD3 protein 20130413 {GO:0060041=IEA, GO:0007601=IEA, GO:0050896=IEA} response to stimulus, retina development in camera-type eye, visual perception Human Ensembl:ENSMUSP00000050188 RDH10 Reactome UniProtKB {GO:0008406=GO_REF:0000019, GO:0001656=GO_REF:0000019, GO:0007603=Reactome:REACT_160125, GO:0005634=PMID:19458327, GO:0048703=GO_REF:0000019, GO:0043583=GO_REF:0000019, GO:0031076=GO_REF:0000019, GO:0060431=GO_REF:0000019, GO:0005737=PMID:19458327, GO:0014032=GO_REF:0000019, GO:0042574=PMID:19458327, GO:0042572=PMID:19458327, GO:0004745=PMID:12407145, GO:0002138=GO_REF:0000019, GO:0052650=GO_REF:0000003, GO:0001701=GO_REF:0000019, GO:0001523=Reactome:REACT_160156, GO:0044297=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0005789=Reactome:REACT_160138, GO:0035115=GO_REF:0000019, GO:0060449=GO_REF:0000019, GO:0016021=PMID:19458327, GO:0007601=PMID:12407145, GO:0043584=GO_REF:0000019} Q8IZV5 Retinol dehydrogenase 10 protein 20130301 {GO:0008406=IEA, GO:0001656=IEA, GO:0007603=TAS, GO:0005634=IDA, GO:0048703=IEA, GO:0043583=IEA, GO:0031076=IEA, GO:0060431=IEA, GO:0005737=IDA, GO:0014032=IEA, GO:0042574=IDA, GO:0042572=IDA, GO:0004745=IDA, GO:0002138=IEA, GO:0052650=IEA, GO:0001701=IEA, GO:0001523=TAS, GO:0044297=IEA, GO:0016020=IEA, GO:0005789=TAS, GO:0035115=IEA, GO:0060449=IEA, GO:0016021=IDA, GO:0007601=IDA, GO:0043584=IEA} bud elongation involved in lung branching, ear development, embryonic camera-type eye development, embryonic forelimb morphogenesis, embryonic viscerocranium morphogenesis, gonad development, in utero embryonic development, metanephros development, neural crest cell development, nose development, phototransduction, visible light, primary lung bud formation, retinal metabolic process, retinoic acid biosynthetic process, retinoid metabolic process, retinol metabolic process, visual perception cell body, cytoplasm, endoplasmic reticulum membrane, integral to membrane, membrane, nucleus NADP-retinol dehydrogenase activity, retinol dehydrogenase activity Human RDH11 Reactome UniProtKB {GO:0005622=GO_REF:0000024, GO:0016062=GO_REF:0000019, GO:0001917=GO_REF:0000019, GO:0007603=Reactome:REACT_160125, GO:0042574=PMID:12807874, GO:0042572=GO_REF:0000024, GO:0005789=Reactome:REACT_160138, GO:0016491=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0052650=PMID:12807874, GO:0004745=GO_REF:0000024, GO:0001523=Reactome:REACT_160156} Q8TC12 Retinol dehydrogenase 11 protein 20130301 {GO:0005622=ISS, GO:0016062=IEA, GO:0001917=IEA, GO:0007603=TAS, GO:0042574=IDA, GO:0042572=ISS, GO:0005789=TAS, GO:0016491=IEA, GO:0016021=IEA, GO:0052650=IDA, GO:0004745=ISS, GO:0001523=TAS} adaptation of rhodopsin mediated signaling, phototransduction, visible light, retinal metabolic process, retinoid metabolic process, retinol metabolic process endoplasmic reticulum membrane, integral to membrane, intracellular, photoreceptor inner segment NADP-retinol dehydrogenase activity, oxidoreductase activity, retinol dehydrogenase activity Human RDH12 Reactome UniProtKB {GO:0005622=PMID:12226107, GO:0007603=Reactome:REACT_160125, GO:0042572=PMID:12226107, GO:0045494=PMID:12226107, GO:0004745=PMID:12226107, GO:0001523=Reactome:REACT_160156, GO:0007601=PMID:12226107, GO:0060342=Reactome:REACT_160140} Q96NR8 Retinol dehydrogenase 12 protein 20120924 {GO:0005622=IDA, GO:0007603=TAS, GO:0042572=IDA, GO:0045494=TAS, GO:0004745=IDA, GO:0001523=TAS, GO:0007601=TAS, GO:0060342=TAS} photoreceptor cell maintenance, phototransduction, visible light, retinoid metabolic process, retinol metabolic process, visual perception intracellular, photoreceptor inner segment membrane retinol dehydrogenase activity Human RDH13 UniProtKB UniProtKB {GO:0016491=GO_REF:0000037} Q8NBN7 Retinol dehydrogenase 13 protein 20130413 {GO:0016491=IEA} oxidoreductase activity Human UniProtKB-KW:KW-0560 RDH14 LIFEdb UniProtKB {GO:0005739=GO_REF:0000019, GO:0005783=GO_REF:0000054, GO:0016491=GO_REF:0000037} Q9HBH5 Retinol dehydrogenase 14 protein 20100607 {GO:0005739=IEA, GO:0005783=IDA, GO:0016491=IEA} endoplasmic reticulum, mitochondrion oxidoreductase activity Human RDH5 Reactome UniProtKB {GO:0007603=Reactome:REACT_160125, GO:0042572=GO_REF:0000041, GO:0005789=Reactome:REACT_160124, GO:0016491=GO_REF:0000002, GO:0005788=GO_REF:0000039, GO:0004745=PMID:9115228, GO:0001523=Reactome:REACT_160156, GO:0007601=GO_REF:0000037} Q92781 11-cis retinol dehydrogenase protein 20130301 {GO:0007603=TAS, GO:0042572=IEA, GO:0005789=TAS, GO:0016491=IEA, GO:0005788=IEA, GO:0004745=TAS, GO:0001523=TAS, GO:0007601=IEA} phototransduction, visible light, retinoid metabolic process, retinol metabolic process, visual perception endoplasmic reticulum lumen, endoplasmic reticulum membrane oxidoreductase activity, retinol dehydrogenase activity Human RDM1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0015030=GO_REF:0000039, GO:0006281=GO_REF:0000002, GO:0000166=GO_REF:0000002, GO:0016605=GO_REF:0000039, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0006310=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037} Q8NG50 RAD52 motif-containing protein 1 protein 20101115 {GO:0005737=IDA, GO:0015030=IEA, GO:0006281=IEA, GO:0000166=IEA, GO:0016605=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0006310=IEA, GO:0003676=IEA, GO:0003677=IEA} DNA recombination, DNA repair Cajal body, PML body, cytoplasm, nucleolus DNA binding, RNA binding, nucleic acid binding, nucleotide binding Human RDX HPA UniProtKB {GO:0005515=PMID:21282464, GO:0008092=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0030033=GO_REF:0000019, GO:0032420=GO_REF:0000019, GO:0045177=GO_REF:0000019, GO:0045176=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0030175=GO_REF:0000019, GO:0032154=GO_REF:0000039, GO:0001726=GO_REF:0000019, GO:0030027=GO_REF:0000019, GO:0051693=GO_REF:0000037, GO:0005737=GO_REF:0000037, GO:0005856=GO_REF:0000039, GO:0005925=PMID:21282464, GO:0019898=GO_REF:0000002} P35241 Radixin protein 20120912 {GO:0005515=IPI, GO:0008092=IEA, GO:0005886=IDA, GO:0030033=IEA, GO:0032420=IEA, GO:0045177=IEA, GO:0045176=IEA, GO:0003779=IEA, GO:0030175=IEA, GO:0032154=IEA, GO:0001726=IEA, GO:0030027=IEA, GO:0051693=IEA, GO:0005737=IEA, GO:0005856=IEA, GO:0005925=IDA, GO:0019898=IEA} actin filament capping, apical protein localization, microvillus assembly apical part of cell, cleavage furrow, cytoplasm, cytoskeleton, extrinsic to membrane, filopodium, focal adhesion, lamellipodium, plasma membrane, ruffle, stereocilium actin binding, cytoskeletal protein binding, protein binding Human REC8 PINC UniProtKB {GO:0007286=GO_REF:0000019, GO:0005634=PMID:10207075, GO:0000800=GO_REF:0000019, GO:0001556=GO_REF:0000019, GO:0007283=PMID:10207075, GO:0007129=GO_REF:0000019, GO:0007126=PMID:10207075, GO:0007062=PMID:10207075, GO:0034991=GO_REF:0000019, GO:0000778=GO_REF:0000019, GO:0001673=GO_REF:0000019, GO:0007141=GO_REF:0000019, GO:0007131=PMID:10207075} O95072 Meiotic recombination protein REC8 homolog protein 20030904 {GO:0007286=IEA, GO:0005634=TAS, GO:0000800=IEA, GO:0001556=IEA, GO:0007283=TAS, GO:0007129=IEA, GO:0007126=TAS, GO:0007062=TAS, GO:0034991=IEA, GO:0000778=IEA, GO:0001673=IEA, GO:0007141=IEA, GO:0007131=TAS} male meiosis I, meiosis, oocyte maturation, reciprocal meiotic recombination, sister chromatid cohesion, spermatid development, spermatogenesis, synapsis condensed nuclear chromosome kinetochore, lateral element, male germ cell nucleus, nuclear meiotic cohesin complex, nucleus Human RECK GOC UniProtKB {GO:0010951=PMID:9789069, GO:0004866=PMID:9789069, GO:0016020=PMID:9789069, GO:0005886=GO_REF:0000039, GO:0030198=GO_REF:0000019, GO:0007566=GO_REF:0000019, GO:0004867=GO_REF:0000037, GO:0008191=PMID:9789069, GO:0031225=GO_REF:0000037, GO:0001955=GO_REF:0000019} O95980 Reversion-inducing cysteine-rich protein with Kazal motifs protein 20130413 {GO:0010951=IDA, GO:0004866=IDA, GO:0016020=TAS, GO:0005886=IEA, GO:0030198=IEA, GO:0007566=IEA, GO:0004867=IEA, GO:0008191=TAS, GO:0031225=IEA, GO:0001955=IEA} blood vessel maturation, embryo implantation, extracellular matrix organization, negative regulation of endopeptidase activity anchored to membrane, membrane, plasma membrane endopeptidase inhibitor activity, metalloendopeptidase inhibitor activity, serine-type endopeptidase inhibitor activity Human RECQL GOC UniProtKB {GO:0008026=GO_REF:0000002, GO:0005515=PMID:15886194, GO:0043140=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0006310=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0003678=PMID:11562355, GO:0006260=GO_REF:0000002, GO:0000733=PMID:19177149, GO:0006281=GO_REF:0000002, GO:0004003=PMID:7961977, GO:0015630=GO_REF:0000052, GO:0032508=PMID:7527136} P46063 ATP-dependent DNA helicase Q1 protein 20130413 {GO:0008026=IEA, GO:0005515=IPI, GO:0043140=IEA, GO:0005730=IDA, GO:0006310=IEA, GO:0005634=IDA, GO:0003676=IEA, GO:0005524=IEA, GO:0003677=IEA, GO:0003678=IDA, GO:0006260=IEA, GO:0000733=IDA, GO:0006281=IEA, GO:0004003=TAS, GO:0015630=IDA, GO:0032508=TAS} DNA duplex unwinding, DNA recombination, DNA repair, DNA replication, DNA strand renaturation microtubule cytoskeleton, nucleolus, nucleus ATP binding, ATP-dependent 3'-5' DNA helicase activity, ATP-dependent DNA helicase activity, ATP-dependent helicase activity, DNA binding, DNA helicase activity, nucleic acid binding, protein binding Human RECQL4 PINC UniProtKB {GO:0006260=PMID:19177149, GO:0000733=PMID:19177149, GO:0043140=PMID:19177149, GO:0005737=GO_REF:0000039, GO:0006281=PMID:9878247, GO:0000405=PMID:19177149, GO:0007275=PMID:10319867, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0006310=GO_REF:0000002, GO:0032508=PMID:19177149, GO:0005524=PMID:19177149} O94761 ATP-dependent DNA helicase Q4 protein 20030904 {GO:0006260=IDA, GO:0000733=IDA, GO:0043140=IMP, GO:0005737=IEA, GO:0006281=TAS, GO:0000405=IDA, GO:0007275=TAS, GO:0005634=IEA, GO:0008270=IEA, GO:0006310=IEA, GO:0032508=IDA, GO:0005524=IDA} DNA duplex unwinding, DNA recombination, DNA repair, DNA replication, DNA strand renaturation, multicellular organismal development cytoplasm, nucleus ATP binding, ATP-dependent 3'-5' DNA helicase activity, bubble DNA binding, zinc ion binding Human RECQL5 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0031965=GO_REF:0000052, GO:0004386=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0006310=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0006259=PMID:10710432, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000038, GO:0003678=PMID:10710432, GO:0005737=GO_REF:0000052, GO:0006281=PMID:9878247, GO:0016591=PMID:22231121, GO:0005654=PMID:10710432, GO:0032508=PMID:9878247} Q6P4G0 RecQ protein-like 5 protein 20130413 {GO:0008026=IEA, GO:0031965=IDA, GO:0004386=IEA, GO:0005730=IDA, GO:0006310=IEA, GO:0005634=IDA, GO:0006259=NAS, GO:0003676=IEA, GO:0005524=IEA, GO:0003678=NAS, GO:0005737=IDA, GO:0006281=TAS, GO:0016591=IDA, GO:0005654=NAS, GO:0032508=TAS} DNA duplex unwinding, DNA metabolic process, DNA recombination, DNA repair DNA-directed RNA polymerase II, holoenzyme, cytoplasm, nuclear membrane, nucleolus, nucleoplasm, nucleus ATP binding, ATP-dependent helicase activity, DNA helicase activity, helicase activity, nucleic acid binding Human UniProtKB-KW:KW-0067 REEP1 HGNC UniProtKB {GO:0005515=PMID:20200447, GO:0008017=PMID:20200447, GO:0008219=GO_REF:0000037, GO:0005737=PMID:15550249, GO:0031966=GO_REF:0000039, GO:0016020=PMID:20200447, GO:0005783=PMID:20200447, GO:0051205=PMID:15550249, GO:0071786=PMID:20200447, GO:0016021=GO_REF:0000037, GO:0031849=PMID:15550249} Q9H902 Receptor expression-enhancing protein 1 protein 20061106 {GO:0005515=IPI, GO:0008017=IDA, GO:0008219=IEA, GO:0005737=IDA, GO:0031966=IEA, GO:0016020=IDA, GO:0005783=IDA, GO:0051205=IDA, GO:0071786=IMP, GO:0016021=IEA, GO:0031849=IMP} cell death, endoplasmic reticulum tubular network organization, protein insertion into membrane cytoplasm, endoplasmic reticulum, integral to membrane, membrane, mitochondrial membrane microtubule binding, olfactory receptor binding, protein binding Human REEP2 UniProtKB UniProtKB {GO:0005881=PMID:23264731, GO:0050913=GO_REF:0000019, GO:0005887=GO_REF:0000019, GO:0031883=GO_REF:0000019, GO:0050916=GO_REF:0000019, GO:0032596=GO_REF:0000019} Q9BRK0 Receptor expression-enhancing protein 2 protein 20130311 {GO:0005881=IDA, GO:0050913=IEA, GO:0005887=IEA, GO:0031883=IEA, GO:0050916=IEA, GO:0032596=IEA} protein transport into membrane raft, sensory perception of bitter taste, sensory perception of sweet taste cytoplasmic microtubule, integral to plasma membrane taste receptor binding Human REEP3 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q6NUK4 Receptor expression-enhancing protein 3 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 REEP4 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9H6H4 Receptor expression-enhancing protein 4 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 REEP5 IntAct UniProtKB {GO:0005515=PMID:16762630, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0016021=GO_REF:0000029} Q00765 Receptor expression-enhancing protein 5 protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0003674=ND, GO:0016021=NAS} biological_process integral to membrane molecular_function, protein binding Human UniProtKB:Q6P1Q0 REEP6 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q96HR9 Receptor expression-enhancing protein 6 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 REG1A MGI UniProtKB {GO:0008284=PMID:2332435, GO:0030246=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0008083=PMID:10526060} P05451 Lithostathine-1-alpha protein 20080910 {GO:0008284=TAS, GO:0030246=IEA, GO:0005576=IEA, GO:0008083=IDA} positive regulation of cell proliferation extracellular region carbohydrate binding, growth factor activity Human REG1B PINC UniProtKB {GO:0008283=PMID:2963000, GO:0030246=GO_REF:0000002, GO:0005576=GO_REF:0000039} P48304 Lithostathine-1-beta protein 20030904 {GO:0008283=TAS, GO:0030246=IEA, GO:0005576=IEA} cell proliferation extracellular region carbohydrate binding Human REG3A PINC UniProtKB {GO:0005737=PMID:8997243, GO:0008283=PMID:8997243, GO:0030246=GO_REF:0000002, GO:0007275=PMID:8997243, GO:0006953=GO_REF:0000037, GO:0005615=PMID:8997243, GO:0007157=PMID:8997243} Q06141 Regenerating islet-derived protein 3-alpha protein 20030904 {GO:0005737=TAS, GO:0008283=TAS, GO:0030246=IEA, GO:0007275=TAS, GO:0006953=IEA, GO:0005615=TAS, GO:0007157=TAS} acute-phase response, cell proliferation, heterophilic cell-cell adhesion, multicellular organismal development cytoplasm, extracellular space carbohydrate binding Human REL UniProtKB UniProtKB {GO:0005515=PMID:15799966, GO:0045084=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0005634=GO_REF:0000038, GO:0005654=Reactome:REACT_118705, GO:0043123=PMID:12761501, GO:0045893=GO_REF:0000019, GO:0001816=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0005829=Reactome:REACT_118856} Q17RU2 REL protein protein 20130413 {GO:0005515=IPI, GO:0045084=IEA, GO:0003700=IEA, GO:0005634=IEA, GO:0005654=TAS, GO:0043123=IEP, GO:0045893=IEA, GO:0001816=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0005829=TAS} cytokine production, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of interleukin-12 biosynthetic process, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent cytosol, nucleoplasm, nucleus DNA binding, protein binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-KW:KW-0539 RELA UniProtKB UniProtKB {GO:0005515=PMID:21903422, GO:0042542=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0044212=PMID:17350185, GO:0003705=PMID:3091258, GO:0019221=PMID:15876188, GO:0033590=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0051591=GO_REF:0000019, GO:0042802=PMID:10498867, GO:0002756=Reactome:REACT_6809, GO:0051607=PMID:8717528, GO:0002755=Reactome:REACT_27215, GO:0071356=PMID:18073330, GO:0009887=GO_REF:0000019, GO:0043123=PMID:12761501, GO:0001942=GO_REF:0000019, GO:0031625=PMID:12748188, GO:0071532=GO_REF:0000019, GO:0032868=GO_REF:0000019, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0019901=PMID:15465828, GO:0034134=Reactome:REACT_7980, GO:0007568=GO_REF:0000019, GO:0070431=PMID:12527755, GO:0006952=GO_REF:0000019, GO:0043278=GO_REF:0000019, GO:0002224=Reactome:REACT_9020, GO:0001889=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0045084=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0071347=PMID:18073330, GO:0042301=PMID:10521409, GO:0032570=GO_REF:0000019, GO:0035666=Reactome:REACT_25281, GO:0034166=Reactome:REACT_9027, GO:0005654=Reactome:REACT_118705, GO:0045893=PMID:17350185, GO:0045892=PMID:17350185, GO:0034162=Reactome:REACT_9047, GO:0008134=PMID:10849440, GO:0050852=Reactome:REACT_12526, GO:0008284=GO_REF:0000019, GO:0034142=Reactome:REACT_6894, GO:0031293=Reactome:REACT_13443, GO:0005634=GO_REF:0000038, GO:0005829=Reactome:REACT_118856, GO:0005737=PMID:15790681, GO:0051092=Reactome:REACT_21281, GO:0006954=PMID:12924514, GO:0045944=PMID:21310825, GO:0070491=PMID:10660609, GO:0032481=Reactome:REACT_118823, GO:0032332=GO_REF:0000019, GO:0033613=PMID:15489227, GO:0034097=GO_REF:0000019, GO:0034138=Reactome:REACT_6783, GO:0043200=GO_REF:0000019, GO:0070555=PMID:15489227, GO:0005667=PMID:12048232, GO:0048011=Reactome:REACT_13776, GO:0043066=PMID:21310825, GO:0010033=PMID:10747850, GO:0014040=GO_REF:0000019, GO:0051059=PMID:8441377, GO:0042177=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0046627=GO_REF:0000019, GO:0050727=GO_REF:0000024, GO:0003677=PMID:15790681, GO:0009612=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0006968=PMID:8717528, GO:0071222=GO_REF:0000019, GO:0047485=PMID:7739562, GO:0010224=PMID:15616591, GO:0003682=PMID:19058135, GO:0006117=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0032495=GO_REF:0000019, GO:0034146=Reactome:REACT_9061} Q2TAM5 Transcription factor p65 protein 20130413 {GO:0005515=IPI, GO:0042542=IEA, GO:0003700=IEA, GO:0044212=IDA, GO:0003705=IDA, GO:0019221=IDA, GO:0033590=IEA, GO:0032403=IEA, GO:0051591=IEA, GO:0042802=IPI, GO:0002756=TAS, GO:0051607=NAS, GO:0002755=TAS, GO:0071356=IDA, GO:0009887=IEA, GO:0043123=IEP, GO:0001942=IEA, GO:0031625=IPI, GO:0071532=IEA, GO:0032868=IEA, GO:0038124=TAS, GO:0038123=TAS, GO:0019901=IPI, GO:0034134=TAS, GO:0007568=IEA, GO:0070431=IDA, GO:0006952=IEA, GO:0043278=IEA, GO:0002224=TAS, GO:0001889=IEA, GO:0043234=IEA, GO:0045084=IEA, GO:0045087=TAS, GO:0071347=IDA, GO:0042301=IDA, GO:0032570=IEA, GO:0035666=TAS, GO:0034166=TAS, GO:0005654=TAS, GO:0045893=IDA, GO:0045892=IDA, GO:0034162=TAS, GO:0008134=IPI, GO:0050852=TAS, GO:0008284=IEA, GO:0034142=TAS, GO:0031293=TAS, GO:0005634=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0051092=TAS, GO:0006954=IDA, GO:0045944=IMP, GO:0070491=IPI, GO:0032481=TAS, GO:0032332=IEA, GO:0033613=IPI, GO:0034097=IEA, GO:0034138=TAS, GO:0043200=IEA, GO:0070555=IGI, GO:0005667=IDA, GO:0048011=TAS, GO:0043066=IMP, GO:0010033=IDA, GO:0014040=IEA, GO:0051059=IPI, GO:0042177=IEA, GO:0042493=IEA, GO:0046627=IEA, GO:0050727=ISS, GO:0003677=IDA, GO:0009612=IEA, GO:0043565=IEA, GO:0006968=NAS, GO:0071222=IEA, GO:0047485=IPI, GO:0010224=IDA, GO:0003682=IDA, GO:0006117=IEA, GO:0019048=IEA, GO:0032495=IEA, GO:0034146=TAS} MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, T cell receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, acetaldehyde metabolic process, aging, cellular defense response, cellular response to interleukin-1, cellular response to lipopolysaccharide, cellular response to tumor necrosis factor, cytokine-mediated signaling pathway, defense response, defense response to virus, hair follicle development, inflammatory response, innate immune response, liver development, membrane protein intracellular domain proteolysis, negative regulation of apoptotic process, negative regulation of insulin receptor signaling pathway, negative regulation of protein catabolic process, negative regulation of transcription, DNA-dependent, neurotrophin TRK receptor signaling pathway, nucleotide-binding oligomerization domain containing 2 signaling pathway, organ morphogenesis, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of Schwann cell differentiation, positive regulation of cell proliferation, positive regulation of chondrocyte differentiation, positive regulation of interleukin-12 biosynthetic process, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of type I interferon production, regulation of inflammatory response, response to UV-B, response to amino acid stimulus, response to cAMP, response to cobalamin, response to cytokine stimulus, response to drug, response to hydrogen peroxide, response to insulin stimulus, response to interleukin-1, response to mechanical stimulus, response to morphine, response to muramyl dipeptide, response to organic substance, response to progesterone stimulus, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, virus-host interaction cytoplasm, cytosol, nucleoplasm, nucleus, protein complex, transcription factor complex DNA binding, NF-kappaB binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, activating transcription factor binding, ankyrin repeat binding, chromatin binding, identical protein binding, phosphate ion binding, protein N-terminus binding, protein binding, protein complex binding, protein kinase binding, repressing transcription factor binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding, ubiquitin protein ligase binding Human UniProtKB-KW:KW-0539 RELB IntAct UniProtKB {GO:0005515=PMID:21217772, GO:0010628=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0005815=GO_REF:0000039, GO:0045063=GO_REF:0000019, GO:0019882=GO_REF:0000019, GO:0003714=PMID:1577270, GO:0005634=GO_REF:0000039, GO:0043011=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0005829=GO_REF:0000019} Q01201 Transcription factor RelB protein 20130415 {GO:0005515=IPI, GO:0010628=IEA, GO:0003700=IEA, GO:0005815=IEA, GO:0045063=IEA, GO:0019882=IEA, GO:0003714=TAS, GO:0005634=IEA, GO:0043011=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0005829=IEA} T-helper 1 cell differentiation, antigen processing and presentation, myeloid dendritic cell differentiation, positive regulation of gene expression, transcription, DNA-dependent cytosol, microtubule organizing center, nucleus DNA binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human UniProtKB:P49841 RELL1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0015630=GO_REF:0000052, GO:0016021=GO_REF:0000037} Q8IUW5 RELT-like protein 1 protein 20101115 {GO:0005737=IDA, GO:0005886=IDA, GO:0015630=IDA, GO:0016021=IEA} cytoplasm, integral to membrane, microtubule cytoskeleton, plasma membrane Human RELL2 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0010811=GO_REF:0000019, GO:0005518=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0005604=GO_REF:0000019} Q8NC24 RELT-like protein 2 protein 20130413 {GO:0005886=IEA, GO:0010811=IEA, GO:0005518=IEA, GO:0016021=IEA, GO:0005604=IEA} positive regulation of cell-substrate adhesion basement membrane, integral to membrane, plasma membrane collagen binding Human UniProtKB-SubCell:SL-0039 RELN BHF-UCL UniProtKB {GO:0090129=GO_REF:0000024, GO:0021511=GO_REF:0000024, GO:0032008=GO_REF:0000019, GO:0061098=GO_REF:0000024, GO:0021800=GO_REF:0000024, GO:2000310=GO_REF:0000024, GO:0050731=PMID:10571240, GO:0097120=GO_REF:0000019, GO:0070326=PMID:10571240, GO:0070325=PMID:10571240, GO:0021517=GO_REF:0000019, GO:0005615=GO_REF:0000024, GO:0030425=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0005737=GO_REF:0000024, GO:0097114=GO_REF:0000019, GO:0007411=GO_REF:0000024, GO:0045860=GO_REF:0000024, GO:0006508=GO_REF:0000037, GO:0007155=GO_REF:0000037, GO:0061003=GO_REF:0000024, GO:2000969=GO_REF:0000024, GO:0097119=GO_REF:0000019, GO:0008306=GO_REF:0000019, GO:2000463=GO_REF:0000024, GO:0007616=GO_REF:0000019, GO:0051057=GO_REF:0000024, GO:0051968=GO_REF:0000024, GO:0005578=GO_REF:0000039, GO:0050804=GO_REF:0000024, GO:0014068=GO_REF:0000019, GO:0018108=GO_REF:0000024, GO:1900273=GO_REF:0000024, GO:0007417=GO_REF:0000024, GO:0038026=PMID:10571240, GO:0016358=GO_REF:0000019, GO:0032793=GO_REF:0000024, GO:0021766=GO_REF:0000024, GO:0000904=GO_REF:0000024, GO:0050795=GO_REF:0000024, GO:0007420=GO_REF:0000024, GO:0010976=GO_REF:0000024, GO:0008236=GO_REF:0000037, GO:0010001=GO_REF:0000024, GO:0004712=GO_REF:0000024, GO:0048265=GO_REF:0000024, GO:0001764=GO_REF:0000024} P78509 Reelin protein 20120502 {GO:0090129=ISS, GO:0021511=ISS, GO:0032008=IEA, GO:0061098=ISS, GO:0021800=ISS, GO:2000310=ISS, GO:0050731=ISS, GO:0097120=IEA, GO:0070326=ISS, GO:0070325=ISS, GO:0021517=IEA, GO:0005615=ISS, GO:0030425=ISS, GO:0046872=IEA, GO:0005737=ISS, GO:0097114=IEA, GO:0007411=ISS, GO:0045860=ISS, GO:0006508=IEA, GO:0007155=IEA, GO:0061003=ISS, GO:2000969=ISS, GO:0097119=IEA, GO:0008306=IEA, GO:2000463=ISS, GO:0007616=IEA, GO:0051057=ISS, GO:0051968=ISS, GO:0005578=IEA, GO:0050804=ISS, GO:0014068=IEA, GO:0018108=ISS, GO:1900273=ISS, GO:0007417=ISS, GO:0038026=ISS, GO:0016358=IEA, GO:0032793=ISS, GO:0021766=ISS, GO:0000904=ISS, GO:0050795=ISS, GO:0007420=ISS, GO:0010976=ISS, GO:0008236=IEA, GO:0010001=ISS, GO:0004712=ISS, GO:0048265=ISS, GO:0001764=ISS} N-methyl-D-aspartate receptor clustering, associative learning, axon guidance, brain development, cell adhesion, cell morphogenesis involved in differentiation, central nervous system development, cerebral cortex tangential migration, dendrite development, glial cell differentiation, hippocampus development, long-term memory, neuron migration, peptidyl-tyrosine phosphorylation, positive regulation of CREB transcription factor activity, positive regulation of TOR signaling cascade, positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity, positive regulation of dendritic spine morphogenesis, positive regulation of excitatory postsynaptic membrane potential, positive regulation of long-term synaptic potentiation, positive regulation of neuron projection development, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of protein kinase activity, positive regulation of protein tyrosine kinase activity, positive regulation of small GTPase mediated signal transduction, positive regulation of synapse maturation, positive regulation of synaptic transmission, glutamatergic, postsynaptic density protein 95 clustering, proteolysis, receptor localization to synapse, reelin-mediated signaling pathway, regulation of N-methyl-D-aspartate selective glutamate receptor activity, regulation of behavior, regulation of synaptic transmission, response to pain, spinal cord patterning, ventral spinal cord development cytoplasm, dendrite, extracellular space, proteinaceous extracellular matrix lipoprotein particle receptor binding, metal ion binding, protein serine/threonine/tyrosine kinase activity, serine-type peptidase activity, very-low-density lipoprotein particle receptor binding Human UniProtKB:Q60841 RELT UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q969Z4 Tumor necrosis factor receptor superfamily member 19L protein 20130413 {GO:0005737=IEA, GO:0005886=IEA, GO:0016021=IEA} cytoplasm, integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 REM1 UniProtKB UniProtKB {GO:0005516=GO_REF:0000037, GO:0016020=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037} O75628 GTP-binding protein REM 1 protein 20130413 {GO:0005516=IEA, GO:0016020=IEA, GO:0007264=IEA, GO:0003924=IEA, GO:0005525=IEA} small GTPase mediated signal transduction membrane GTP binding, GTPase activity, calmodulin binding Human UniProtKB-KW:KW-0342 REM2 UniProtKB UniProtKB {GO:0007165=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0003924=GO_REF:0000019, GO:0005525=GO_REF:0000019} Q8IYK8 GTP-binding protein REM 2 protein 20130413 {GO:0007165=IEA, GO:0005886=IEA, GO:0016020=IEA, GO:0007264=IEA, GO:0003924=IEA, GO:0005525=IEA} signal transduction, small GTPase mediated signal transduction membrane, plasma membrane GTP binding, GTPase activity Human UniProtKB-SubCell:SL-0039 REN BHF-UCL UniProtKB {GO:0002003=Reactome:REACT_147707, GO:0005886=Reactome:REACT_147891, GO:0005159=GO_REF:0000019, GO:0070305=GO_REF:0000019, GO:0051591=GO_REF:0000019, GO:0005615=PMID:12045255, GO:0002018=GO_REF:0000019, GO:0043408=PMID:12045255, GO:0006508=PMID:12045255, GO:0032496=GO_REF:0000019, GO:0048469=GO_REF:0000019, GO:0001822=PMID:16116425, GO:0001823=GO_REF:0000019, GO:0006950=GO_REF:0000019, GO:0005102=PMID:12045255, GO:0005576=Reactome:REACT_147869, GO:0035690=GO_REF:0000019, GO:0050435=GO_REF:0000019, GO:0044444=GO_REF:0000019, GO:0009755=GO_REF:0000019, GO:0042756=GO_REF:0000019, GO:0008217=PMID:7584914, GO:0008233=PMID:12045255, GO:0004190=Reactome:REACT_147720, GO:0044267=Reactome:REACT_17015, GO:0008584=GO_REF:0000019} P00797 Renin protein 20080519 {GO:0002003=TAS, GO:0005886=TAS, GO:0005159=IEA, GO:0070305=IEA, GO:0051591=IEA, GO:0005615=IDA, GO:0002018=IEA, GO:0043408=IDA, GO:0006508=IDA, GO:0032496=IEA, GO:0048469=IEA, GO:0001822=IMP, GO:0001823=IEA, GO:0006950=IEA, GO:0005102=IPI, GO:0005576=TAS, GO:0035690=IEA, GO:0050435=IEA, GO:0044444=IEA, GO:0009755=IEA, GO:0042756=IEA, GO:0008217=TAS, GO:0008233=IDA, GO:0004190=EXP, GO:0044267=TAS, GO:0008584=IEA} angiotensin maturation, beta-amyloid metabolic process, cell maturation, cellular protein metabolic process, cellular response to drug, drinking behavior, hormone-mediated signaling pathway, kidney development, male gonad development, mesonephros development, proteolysis, regulation of MAPK cascade, regulation of blood pressure, renin-angiotensin regulation of aldosterone production, response to cAMP, response to cGMP, response to lipopolysaccharide, response to stress cytoplasmic part, extracellular region, extracellular space, plasma membrane aspartic-type endopeptidase activity, insulin-like growth factor receptor binding, peptidase activity, receptor binding Human RENBP PINC UniProtKB {GO:0004866=PMID:9285790, GO:0050121=GO_REF:0000024, GO:0006051=GO_REF:0000019, GO:0008217=PMID:9285790, GO:0006044=GO_REF:0000019, GO:0003824=GO_REF:0000002, GO:0019262=PMID:22692205, GO:0005524=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0006013=GO_REF:0000002, GO:0004476=GO_REF:0000002} P51606 N-acylglucosamine 2-epimerase protein 20030904 {GO:0004866=TAS, GO:0050121=ISS, GO:0006051=IEA, GO:0008217=TAS, GO:0006044=IEA, GO:0003824=IEA, GO:0019262=TAS, GO:0005524=IEA, GO:0042803=IEA, GO:0006013=IEA, GO:0004476=IEA} N-acetylglucosamine metabolic process, N-acetylmannosamine metabolic process, N-acetylneuraminate catabolic process, mannose metabolic process, regulation of blood pressure ATP binding, N-acylglucosamine 2-epimerase activity, catalytic activity, endopeptidase inhibitor activity, mannose-6-phosphate isomerase activity, protein homodimerization activity Human REPIN1 HPA UniProtKB {GO:0006260=GO_REF:0000037, GO:0005811=GO_REF:0000019, GO:0031965=GO_REF:0000019, GO:2001273=GO_REF:0000019, GO:0022626=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0005664=PMID:10606657, GO:2000191=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037} Q9BWE0 Replication initiator 1 protein 20101115 {GO:0006260=IEA, GO:0005811=IEA, GO:0031965=IEA, GO:2001273=IEA, GO:0022626=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0005664=TAS, GO:2000191=IEA, GO:0003676=IEA, GO:0003677=IEA} DNA replication, regulation of fatty acid transport, regulation of glucose import in response to insulin stimulus cytosolic ribosome, lipid particle, nuclear membrane, nuclear origin of replication recognition complex, nucleus DNA binding, nucleic acid binding, zinc ion binding Human REPS1 UniProtKB UniProtKB {GO:0005515=PMID:20946875, GO:0005905=PMID:20946875, GO:0017124=PMID:20946875, GO:0005886=PMID:20946875, GO:0005509=GO_REF:0000002, GO:0006898=GO_REF:0000002} Q96D71 RalBP1-associated Eps domain-containing protein 1 protein 20101125 {GO:0005515=IPI, GO:0005905=IDA, GO:0017124=IPI, GO:0005886=IDA, GO:0005509=IEA, GO:0006898=IEA} receptor-mediated endocytosis coated pit, plasma membrane SH3 domain binding, calcium ion binding, protein binding Human REPS2 PINC UniProtKB {GO:0005515=PMID:9422736, GO:0005737=GO_REF:0000039, GO:0006461=PMID:9422736, GO:0007173=PMID:9422736, GO:0005509=GO_REF:0000002, GO:0006898=GO_REF:0000002} Q8NFH8 RalBP1-associated Eps domain-containing protein 2 protein 20050308 {GO:0005515=IPI, GO:0005737=IEA, GO:0006461=TAS, GO:0007173=TAS, GO:0005509=IEA, GO:0006898=IEA} epidermal growth factor receptor signaling pathway, protein complex assembly, receptor-mediated endocytosis cytoplasm calcium ion binding, protein binding Human RER1 InterPro UniProtKB {GO:0003674=GO_REF:0000015, GO:0030173=PMID:9309388, GO:0006890=PMID:9309388, GO:0016021=GO_REF:0000002} Q5T093 Protein RER1 protein 20130413 {GO:0003674=ND, GO:0030173=IDA, GO:0006890=IDA, GO:0016021=IEA} retrograde vesicle-mediated transport, Golgi to ER integral to Golgi membrane, integral to membrane molecular_function Human InterPro:IPR004932 RERE HPA UniProtKB {GO:0005515=PMID:16713569, GO:0003700=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0007275=GO_REF:0000037, GO:0006607=PMID:10814707, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0008267=PMID:10814707, GO:0043565=GO_REF:0000002, GO:0005739=GO_REF:0000052, GO:0000118=GO_REF:0000019, GO:0003682=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0006338=GO_REF:0000019} Q9P2R6 Arginine-glutamic acid dipeptide repeats protein protein 20100326 {GO:0005515=IPI, GO:0003700=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0007275=IEA, GO:0006607=TAS, GO:0003677=IEA, GO:0006351=IEA, GO:0008267=TAS, GO:0043565=IEA, GO:0005739=IDA, GO:0000118=IEA, GO:0003682=IEA, GO:0008270=IEA, GO:0006338=IEA} NLS-bearing substrate import into nucleus, chromatin remodeling, multicellular organismal development, transcription, DNA-dependent histone deacetylase complex, mitochondrion, nucleolus, nucleus DNA binding, chromatin binding, poly-glutamine tract binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human REST HPA UniProtKB {GO:0005515=PMID:12192000, GO:0008285=PMID:20564196, GO:0003700=PMID:19342457, GO:0044212=PMID:17555596, GO:0005634=GO_REF:0000052, GO:0005829=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0015271=PMID:18570921, GO:0071257=PMID:18570921, GO:0050768=GO_REF:0000024, GO:2000798=PMID:20942606, GO:0017053=PMID:10734093, GO:0060379=GO_REF:0000024, GO:0001046=PMID:8568247, GO:0046676=PMID:20942606, GO:0006355=PMID:7871435, GO:0070933=PMID:17555596, GO:2000706=GO_REF:0000024, GO:0043065=PMID:20564196, GO:2000740=PMID:18570921, GO:0005730=GO_REF:0000052, GO:0001047=PMID:17984088, GO:0000122=PMID:21284946, GO:0035690=PMID:20564196, GO:0043922=PMID:17555596, GO:0043280=PMID:20564196, GO:0071385=PMID:17984088, GO:0001078=PMID:21284946, GO:0045955=GO_REF:0000024, GO:0045665=PMID:18570921, GO:0003682=GO_REF:0000024, GO:0010629=PMID:20564196, GO:2000065=PMID:19342457, GO:0008270=GO_REF:0000002, GO:0045893=PMID:17984088, GO:0045892=PMID:17984088, GO:0008134=PMID:17130167, GO:0032348=PMID:19342457} Q13127 RE1-silencing transcription factor protein 20101115 {GO:0005515=IPI, GO:0008285=IMP, GO:0003700=IDA, GO:0044212=IDA, GO:0005634=IDA, GO:0005829=IEA, GO:0005737=IDA, GO:0015271=IMP, GO:0071257=IMP, GO:0050768=ISS, GO:2000798=IMP, GO:0017053=IDA, GO:0060379=ISS, GO:0001046=IDA, GO:0046676=IMP, GO:0006355=NAS, GO:0070933=IDA, GO:2000706=ISS, GO:0043065=IMP, GO:2000740=IMP, GO:0005730=IDA, GO:0001047=IDA, GO:0000122=IDA, GO:0035690=IMP, GO:0043922=IDA, GO:0043280=IMP, GO:0071385=IDA, GO:0001078=IDA, GO:0045955=ISS, GO:0045665=IMP, GO:0003682=ISS, GO:0010629=IMP, GO:2000065=IMP, GO:0008270=IEA, GO:0045893=IDA, GO:0045892=IDA, GO:0008134=IPI, GO:0032348=IMP} cardiac muscle cell myoblast differentiation, cellular response to drug, cellular response to electrical stimulus, cellular response to glucocorticoid stimulus, histone H4 deacetylation, negative regulation by host of viral transcription, negative regulation of aldosterone biosynthetic process, negative regulation of amniotic stem cell differentiation, negative regulation of calcium ion-dependent exocytosis, negative regulation of cell proliferation, negative regulation of cortisol biosynthetic process, negative regulation of dense core granule biogenesis, negative regulation of gene expression, negative regulation of insulin secretion, negative regulation of mesenchymal stem cell differentiation, negative regulation of neurogenesis, negative regulation of neuron differentiation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of apoptotic process, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent cytoplasm, cytosol, nucleolus, nucleus, transcriptional repressor complex RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, chromatin binding, core promoter binding, core promoter sequence-specific DNA binding, outward rectifier potassium channel activity, protein binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding, zinc ion binding Human RET BHF-UCL UniProtKB {GO:0005515=PMID:20877310, GO:0001657=GO_REF:0000019, GO:0071300=PMID:17910947, GO:0097021=GO_REF:0000024, GO:0001755=GO_REF:0000019, GO:0001838=GO_REF:0000019, GO:0030155=PMID:21357690, GO:0061146=GO_REF:0000024, GO:0000165=GO_REF:0000019, GO:0033619=PMID:21357690, GO:0004872=PMID:7824936, GO:2001241=PMID:21357690, GO:0072300=PMID:17047028, GO:0007156=GO_REF:0000002, GO:0035799=GO_REF:0000019, GO:0030335=PMID:20702524, GO:0042551=GO_REF:0000019, GO:0005509=PMID:11445581, GO:0033630=PMID:20702524, GO:0005524=GO_REF:0000037, GO:0048484=GO_REF:0000019, GO:0007165=PMID:7824936, GO:0005887=PMID:19823924, GO:0010976=PMID:17910947, GO:0007497=PMID:8114939, GO:0006468=PMID:7824936, GO:0048265=GO_REF:0000024, GO:0004713=PMID:7824936, GO:0004714=GO_REF:0000003, GO:0045893=PMID:17047028, GO:0007169=GO_REF:0000019, GO:0010008=PMID:19823924} P07949 Proto-oncogene tyrosine-protein kinase receptor Ret protein 20110707 {GO:0005515=IPI, GO:0001657=IEA, GO:0071300=IMP, GO:0097021=ISS, GO:0001755=IEA, GO:0001838=IEA, GO:0030155=IDA, GO:0061146=ISS, GO:0000165=IEA, GO:0033619=IDA, GO:0004872=TAS, GO:2001241=TAS, GO:0072300=ISS, GO:0007156=IEA, GO:0035799=IEA, GO:0030335=IDA, GO:0042551=IEA, GO:0005509=IDA, GO:0033630=IDA, GO:0005524=IEA, GO:0048484=IEA, GO:0007165=TAS, GO:0005887=IDA, GO:0010976=IMP, GO:0007497=TAS, GO:0006468=TAS, GO:0048265=ISS, GO:0004713=TAS, GO:0004714=IEA, GO:0045893=ISS, GO:0007169=IEA, GO:0010008=IDA} MAPK cascade, Peyer's patch morphogenesis, cellular response to retinoic acid, embryonic epithelial tube formation, enteric nervous system development, homophilic cell adhesion, lymphocyte migration into lymphoid organs, membrane protein proteolysis, neural crest cell migration, neuron maturation, positive regulation of cell adhesion mediated by integrin, positive regulation of cell migration, positive regulation of extrinsic apoptotic signaling pathway in absence of ligand, positive regulation of metanephric glomerulus development, positive regulation of neuron projection development, positive regulation of transcription, DNA-dependent, posterior midgut development, protein phosphorylation, regulation of cell adhesion, response to pain, signal transduction, transmembrane receptor protein tyrosine kinase signaling pathway, ureter maturation, ureteric bud development endosome membrane, integral to plasma membrane ATP binding, calcium ion binding, protein binding, protein tyrosine kinase activity, receptor activity, transmembrane receptor protein tyrosine kinase activity Human RETN UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0032868=GO_REF:0000019, GO:0005179=GO_REF:0000029, GO:0045444=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0005576=GO_REF:0000029, GO:0005615=GO_REF:0000019} Q9HD89 Resistin protein 20061026 {GO:0008150=ND, GO:0032868=IEA, GO:0005179=NAS, GO:0045444=IEA, GO:0005634=IEA, GO:0005576=NAS, GO:0005615=IEA} biological_process, fat cell differentiation, response to insulin stimulus extracellular region, extracellular space, nucleus hormone activity Human RETNLB UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0005179=GO_REF:0000037, GO:0008283=PMID:11209052, GO:0005576=GO_REF:0000039, GO:0005575=GO_REF:0000015} Q9BQ08 Resistin-like beta protein 20010924 {GO:0003674=ND, GO:0005179=IEA, GO:0008283=NAS, GO:0005576=IEA, GO:0005575=ND} cell proliferation cellular_component, extracellular region hormone activity, molecular_function Human REV1 Reactome UniProtKB {GO:0005515=PMID:22266823, GO:0006260=GO_REF:0000037, GO:0003684=GO_REF:0000002, GO:0042276=PMID:11485998, GO:0000287=GO_REF:0000002, GO:0006281=Reactome:REACT_216, GO:0017125=GO_REF:0000019, GO:0003887=Reactome:REACT_2214, GO:0005654=Reactome:REACT_2214, GO:0009411=PMID:11485998} Q9UBZ9 DNA repair protein REV1 protein 20130201 {GO:0005515=IPI, GO:0006260=IEA, GO:0003684=IEA, GO:0042276=TAS, GO:0000287=IEA, GO:0006281=TAS, GO:0017125=IEA, GO:0003887=TAS, GO:0005654=TAS, GO:0009411=IDA} DNA repair, DNA replication, error-prone translesion synthesis, response to UV nucleoplasm DNA-directed DNA polymerase activity, damaged DNA binding, deoxycytidyl transferase activity, magnesium ion binding, protein binding Human REV3L PINC UniProtKB {GO:0006261=PMID:9618506, GO:0008408=GO_REF:0000033, GO:0051539=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0005694=GO_REF:0000033, GO:0003887=GO_REF:0000033, GO:0016035=PMID:20164194, GO:0006297=GO_REF:0000033, GO:0005634=GO_REF:0000033, GO:0019985=GO_REF:0000033, GO:0003677=GO_REF:0000037, GO:0046872=GO_REF:0000037} O60673 DNA polymerase zeta catalytic subunit protein 20030904 {GO:0006261=TAS, GO:0008408=IBA, GO:0051539=IEA, GO:0000166=IEA, GO:0005694=IBA, GO:0003887=IBA, GO:0016035=IDA, GO:0006297=IBA, GO:0005634=IBA, GO:0019985=IBA, GO:0003677=IEA, GO:0046872=IEA} DNA-dependent DNA replication, nucleotide-excision repair, DNA gap filling, translesion synthesis chromosome, nucleus, zeta DNA polymerase complex 3'-5' exonuclease activity, 4 iron, 4 sulfur cluster binding, DNA binding, DNA-directed DNA polymerase activity, metal ion binding, nucleotide binding Human REXO1 HPA UniProtKB {GO:0004527=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002} Q8N1G1 RNA exonuclease 1 homolog protein 20111111 {GO:0004527=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA} nucleolus, nucleus exonuclease activity, nucleic acid binding NOT Human REXO2 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0008408=PMID:10851236, GO:0006139=PMID:10851236, GO:0004527=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000054, GO:0003676=GO_REF:0000002, GO:0009117=PMID:10851236} Q9Y3B8 Oligoribonuclease, mitochondrial protein 20110516 {GO:0005739=IDA, GO:0008408=IDA, GO:0006139=IDA, GO:0004527=IEA, GO:0005886=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0009117=TAS} nucleobase-containing compound metabolic process, nucleotide metabolic process mitochondrion, nucleolus, nucleus, plasma membrane 3'-5' exonuclease activity, exonuclease activity, nucleic acid binding Human REXO4 LIFEdb UniProtKB {GO:0006355=PMID:10908561, GO:0004527=GO_REF:0000037, GO:0003700=PMID:10908561, GO:0005730=GO_REF:0000054, GO:0005634=PMID:10908561, GO:0003676=GO_REF:0000002} Q9GZR2 RNA exonuclease 4 protein 20100607 {GO:0006355=NAS, GO:0004527=IEA, GO:0003700=NAS, GO:0005730=IDA, GO:0005634=NAS, GO:0003676=IEA} regulation of transcription, DNA-dependent nucleolus, nucleus exonuclease activity, nucleic acid binding, sequence-specific DNA binding transcription factor activity Human RFC1 GOC UniProtKB {GO:0005515=PMID:16438930, GO:0006355=GO_REF:0000037, GO:0003689=GO_REF:0000002, GO:0043085=PMID:8954124, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0006260=GO_REF:0000002, GO:0000084=Reactome:REACT_899, GO:0006261=PMID:8248204, GO:0006271=Reactome:REACT_932, GO:0006281=Reactome:REACT_216, GO:0000723=Reactome:REACT_7970, GO:0006283=Reactome:REACT_1628, GO:0000722=Reactome:REACT_7987, GO:0006297=Reactome:REACT_1998, GO:0005654=Reactome:REACT_8008, GO:0005663=PMID:9488738, GO:0006289=Reactome:REACT_1826, GO:0008047=PMID:8954124, GO:0000278=Reactome:REACT_152, GO:0007004=PMID:8954124, GO:0032201=Reactome:REACT_7961} P35251 Replication factor C subunit 1 protein 20130413 {GO:0005515=IPI, GO:0006355=IEA, GO:0003689=IEA, GO:0043085=TAS, GO:0005524=IEA, GO:0006351=IEA, GO:0006260=IEA, GO:0000084=TAS, GO:0006261=TAS, GO:0006271=TAS, GO:0006281=TAS, GO:0000723=TAS, GO:0006283=TAS, GO:0000722=TAS, GO:0006297=TAS, GO:0005654=TAS, GO:0005663=IDA, GO:0006289=TAS, GO:0008047=TAS, GO:0000278=TAS, GO:0007004=TAS, GO:0032201=TAS} DNA repair, DNA replication, DNA strand elongation involved in DNA replication, DNA-dependent DNA replication, S phase of mitotic cell cycle, mitotic cell cycle, nucleotide-excision repair, nucleotide-excision repair, DNA gap filling, positive regulation of catalytic activity, regulation of transcription, DNA-dependent, telomere maintenance, telomere maintenance via recombination, telomere maintenance via semi-conservative replication, telomere maintenance via telomerase, transcription, DNA-dependent, transcription-coupled nucleotide-excision repair DNA replication factor C complex, nucleoplasm ATP binding, DNA clamp loader activity, enzyme activator activity, protein binding Human RFC2 IntAct UniProtKB {GO:0005515=PMID:15655353, GO:0017111=GO_REF:0000002, GO:0003677=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0006260=Reactome:REACT_6769, GO:0000084=Reactome:REACT_899, GO:0006271=Reactome:REACT_932, GO:0006281=Reactome:REACT_216, GO:0000723=Reactome:REACT_7970, GO:0006283=Reactome:REACT_1628, GO:0000722=Reactome:REACT_7987, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_8008, GO:0006297=Reactome:REACT_1998, GO:0005663=PMID:9488738, GO:0006289=Reactome:REACT_1826, GO:0000278=Reactome:REACT_152, GO:0032201=Reactome:REACT_7961} P35250 Replication factor C subunit 2 protein 20130415 {GO:0005515=IPI, GO:0017111=IEA, GO:0003677=IEA, GO:0005524=IEA, GO:0006260=TAS, GO:0000084=TAS, GO:0006271=TAS, GO:0006281=TAS, GO:0000723=TAS, GO:0006283=TAS, GO:0000722=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0006297=TAS, GO:0005663=IDA, GO:0006289=TAS, GO:0000278=TAS, GO:0032201=TAS} DNA repair, DNA replication, DNA strand elongation involved in DNA replication, S phase of mitotic cell cycle, cell cycle checkpoint, mitotic cell cycle, nucleotide-excision repair, nucleotide-excision repair, DNA gap filling, telomere maintenance, telomere maintenance via recombination, telomere maintenance via semi-conservative replication, transcription-coupled nucleotide-excision repair DNA replication factor C complex, nucleoplasm ATP binding, DNA binding, nucleoside-triphosphatase activity, protein binding Human UniProtKB:P10644 RFC3 GOC UniProtKB {GO:0046683=PMID:16079077, GO:0005515=PMID:9488738, GO:0006200=PMID:9488738, GO:0003689=PMID:9488738, GO:0003677=PMID:9488738, GO:0006260=Reactome:REACT_6769, GO:0000084=Reactome:REACT_899, GO:0006271=Reactome:REACT_932, GO:0006281=Reactome:REACT_216, GO:0000723=Reactome:REACT_7970, GO:0000166=GO_REF:0000002, GO:0006283=Reactome:REACT_1628, GO:0000731=PMID:9488738, GO:0000722=Reactome:REACT_7987, GO:0000075=Reactome:REACT_1538, GO:0006297=Reactome:REACT_1998, GO:0005654=Reactome:REACT_8008, GO:0005663=PMID:9488738, GO:0006289=Reactome:REACT_1826, GO:0000278=Reactome:REACT_152, GO:0016887=PMID:9488738, GO:0032201=Reactome:REACT_7961} P40938 Replication factor C subunit 3 protein 20130413 {GO:0046683=IEP, GO:0005515=IPI, GO:0006200=IDA, GO:0003689=TAS, GO:0003677=IDA, GO:0006260=TAS, GO:0000084=TAS, GO:0006271=TAS, GO:0006281=TAS, GO:0000723=TAS, GO:0000166=IEA, GO:0006283=TAS, GO:0000731=TAS, GO:0000722=TAS, GO:0000075=TAS, GO:0006297=TAS, GO:0005654=TAS, GO:0005663=IDA, GO:0006289=TAS, GO:0000278=TAS, GO:0016887=IDA, GO:0032201=TAS} ATP catabolic process, DNA repair, DNA replication, DNA strand elongation involved in DNA replication, DNA synthesis involved in DNA repair, S phase of mitotic cell cycle, cell cycle checkpoint, mitotic cell cycle, nucleotide-excision repair, nucleotide-excision repair, DNA gap filling, response to organophosphorus, telomere maintenance, telomere maintenance via recombination, telomere maintenance via semi-conservative replication, transcription-coupled nucleotide-excision repair DNA replication factor C complex, nucleoplasm ATPase activity, DNA binding, DNA clamp loader activity, nucleotide binding, protein binding Human RFC4 Reactome UniProtKB {GO:0005515=PMID:9488738, GO:0017111=GO_REF:0000002, GO:0048015=PMID:15504738, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000002, GO:0006260=Reactome:REACT_6769, GO:0000084=Reactome:REACT_899, GO:0006271=Reactome:REACT_932, GO:0006281=Reactome:REACT_216, GO:0000723=Reactome:REACT_7970, GO:0006283=Reactome:REACT_1628, GO:0000722=Reactome:REACT_7987, GO:0000075=Reactome:REACT_1538, GO:0006297=Reactome:REACT_1998, GO:0005654=Reactome:REACT_8008, GO:0005663=PMID:9488738, GO:0006289=Reactome:REACT_1826, GO:0000278=Reactome:REACT_152, GO:0032201=Reactome:REACT_7961} P35249 Replication factor C subunit 4 protein 20130213 {GO:0005515=IPI, GO:0017111=IEA, GO:0048015=NAS, GO:0005524=IEA, GO:0003677=IEA, GO:0006260=TAS, GO:0000084=TAS, GO:0006271=TAS, GO:0006281=TAS, GO:0000723=TAS, GO:0006283=TAS, GO:0000722=TAS, GO:0000075=TAS, GO:0006297=TAS, GO:0005654=TAS, GO:0005663=IDA, GO:0006289=TAS, GO:0000278=TAS, GO:0032201=TAS} DNA repair, DNA replication, DNA strand elongation involved in DNA replication, S phase of mitotic cell cycle, cell cycle checkpoint, mitotic cell cycle, nucleotide-excision repair, nucleotide-excision repair, DNA gap filling, phosphatidylinositol-mediated signaling, telomere maintenance, telomere maintenance via recombination, telomere maintenance via semi-conservative replication, transcription-coupled nucleotide-excision repair DNA replication factor C complex, nucleoplasm ATP binding, DNA binding, nucleoside-triphosphatase activity, protein binding Human RFC5 Reactome UniProtKB {GO:0005515=PMID:9488738, GO:0017111=GO_REF:0000002, GO:0003677=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0006260=Reactome:REACT_6769, GO:0000084=Reactome:REACT_899, GO:0006271=Reactome:REACT_932, GO:0006281=Reactome:REACT_216, GO:0000723=Reactome:REACT_7970, GO:0006283=Reactome:REACT_1628, GO:0000722=Reactome:REACT_7987, GO:0000075=Reactome:REACT_1538, GO:0006297=Reactome:REACT_1998, GO:0005654=Reactome:REACT_8008, GO:0005663=PMID:9488738, GO:0006289=Reactome:REACT_1826, GO:0019899=PMID:8999859, GO:0000278=Reactome:REACT_152, GO:0032201=Reactome:REACT_7961} P40937 Replication factor C subunit 5 protein 20130213 {GO:0005515=IPI, GO:0017111=IEA, GO:0003677=IEA, GO:0005524=IEA, GO:0006260=TAS, GO:0000084=TAS, GO:0006271=TAS, GO:0006281=TAS, GO:0000723=TAS, GO:0006283=TAS, GO:0000722=TAS, GO:0000075=TAS, GO:0006297=TAS, GO:0005654=TAS, GO:0005663=IDA, GO:0006289=TAS, GO:0019899=NAS, GO:0000278=TAS, GO:0032201=TAS} DNA repair, DNA replication, DNA strand elongation involved in DNA replication, S phase of mitotic cell cycle, cell cycle checkpoint, mitotic cell cycle, nucleotide-excision repair, nucleotide-excision repair, DNA gap filling, telomere maintenance, telomere maintenance via recombination, telomere maintenance via semi-conservative replication, transcription-coupled nucleotide-excision repair DNA replication factor C complex, nucleoplasm ATP binding, DNA binding, enzyme binding, nucleoside-triphosphatase activity, protein binding Human RFFL UniPathway UniProtKB {GO:0005737=GO_REF:0000039, GO:0016567=GO_REF:0000041, GO:0016020=GO_REF:0000039, GO:0016874=GO_REF:0000037, GO:0006915=GO_REF:0000037, GO:0008270=GO_REF:0000002} Q8WZ73 E3 ubiquitin-protein ligase rififylin protein 20130413 {GO:0005737=IEA, GO:0016567=IEA, GO:0016020=IEA, GO:0016874=IEA, GO:0006915=IEA, GO:0008270=IEA} apoptotic process, protein ubiquitination cytoplasm, membrane ligase activity, zinc ion binding Human UniPathway:UPA00143 RFK Reactome UniProtKB {GO:0005739=GO_REF:0000019, GO:0008531=Reactome:REACT_11232, GO:0006771=Reactome:REACT_11070, GO:0005737=PMID:12623014, GO:0006766=Reactome:REACT_11193, GO:0006767=Reactome:REACT_11238, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0009398=GO_REF:0000041, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_11232, GO:0009231=PMID:12623014} Q969G6 Riboflavin kinase protein 20130222 {GO:0005739=IEA, GO:0008531=TAS, GO:0006771=TAS, GO:0005737=NAS, GO:0006766=TAS, GO:0006767=TAS, GO:0044281=TAS, GO:0005524=IEA, GO:0009398=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0009231=NAS} FMN biosynthetic process, riboflavin biosynthetic process, riboflavin metabolic process, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cytoplasm, cytosol, mitochondrion ATP binding, metal ion binding, riboflavin kinase activity Human RFPL4A InterPro UniProtKB {GO:0008270=GO_REF:0000002} A6NLU0 Ret finger protein-like 4A protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR001841 RFPL4B InterPro UniProtKB {GO:0008270=GO_REF:0000002} Q6ZWI9 Ret finger protein-like 4B protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR001841 RFT1 Reactome UniProtKB {GO:0008643=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0005319=GO_REF:0000002, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q96AA3 Protein RFT1 homolog protein 20130301 {GO:0008643=IEA, GO:0016021=IEA, GO:0006488=TAS, GO:0044267=TAS, GO:0005319=IEA, GO:0043687=TAS, GO:0018279=TAS} carbohydrate transport, cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine integral to membrane lipid transporter activity Human RFTN1 MGI UniProtKB {GO:0005886=GO_REF:0000039, GO:0045121=PMID:21955986} Q14699 Raftlin protein 20120319 {GO:0005886=IEA, GO:0045121=IDA} membrane raft, plasma membrane Human RFWD2 HPA UniProtKB {GO:0005515=PMID:21625211, GO:0005813=GO_REF:0000052, GO:0016567=GO_REF:0000041, GO:0016874=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005829=Reactome:REACT_20637, GO:0005737=GO_REF:0000052, GO:0016607=GO_REF:0000039, GO:0000075=Reactome:REACT_1538, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_20554, GO:0005925=GO_REF:0000052, GO:0006977=Reactome:REACT_1625} Q8NHY2 E3 ubiquitin-protein ligase RFWD2 protein 20101115 {GO:0005515=IPI, GO:0005813=IDA, GO:0016567=IEA, GO:0016874=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005829=TAS, GO:0005737=IDA, GO:0016607=IEA, GO:0000075=TAS, GO:0008270=IEA, GO:0005654=TAS, GO:0005925=IDA, GO:0006977=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, cell cycle checkpoint, protein ubiquitination centrosome, cytoplasm, cytosol, focal adhesion, nuclear speck, nucleolus, nucleoplasm, nucleus ligase activity, protein binding, zinc ion binding Human RFWD3 UniProtKB UniProtKB {GO:0002039=PMID:20173098, GO:0004842=PMID:20173098, GO:0097371=PMID:20173098, GO:0005737=GO_REF:0000039, GO:0016567=PMID:20173098, GO:0006281=GO_REF:0000037, GO:0010212=PMID:20173098, GO:0016605=GO_REF:0000039, GO:0005634=PMID:20173098, GO:0008270=GO_REF:0000002, GO:0031571=PMID:20173098} Q6PCD5 E3 ubiquitin-protein ligase RFWD3 protein 20100223 {GO:0002039=IPI, GO:0004842=IDA, GO:0097371=IPI, GO:0005737=IEA, GO:0016567=IDA, GO:0006281=IEA, GO:0010212=IDA, GO:0016605=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0031571=IMP} DNA repair, mitotic G1 DNA damage checkpoint, protein ubiquitination, response to ionizing radiation PML body, cytoplasm, nucleus MDM2/MDM4 family protein binding, p53 binding, ubiquitin-protein ligase activity, zinc ion binding Human RFX1 BHF-UCL UniProtKB {GO:0005515=PMID:16289097, GO:0006955=PMID:1505960, GO:0003705=PMID:8289803, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000019} P22670 MHC class II regulatory factor RFX1 protein 20081024 {GO:0005515=IPI, GO:0006955=TAS, GO:0003705=TAS, GO:0005634=IEA, GO:0003677=IEA} immune response nucleus DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, protein binding Human UniProtKB:P35611 RFX2 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P48378 DNA-binding protein RFX2 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding Human UniProtKB-SubCell:SL-0191 RFX3 BHF-UCL UniProtKB {GO:0005515=PMID:20148032, GO:0005667=PMID:20413507, GO:0006355=GO_REF:0000024, GO:0000790=PMID:20413507, GO:0003700=PMID:8600444, GO:0044212=PMID:20148032, GO:0003705=PMID:8289803, GO:0005634=PMID:12411430, GO:0072560=GO_REF:0000019, GO:0003677=PMID:8600444, GO:0006351=GO_REF:0000019, GO:0060287=GO_REF:0000024, GO:0042384=PMID:20413507, GO:0050796=PMID:20413507, GO:0031018=GO_REF:0000024, GO:0045944=PMID:20413507, GO:0060285=GO_REF:0000024, GO:2000078=PMID:20413507, GO:0048469=PMID:20413507, GO:0045893=PMID:20148032, GO:0045892=PMID:12411430} P48380 Transcription factor RFX3 protein 20110124 {GO:0005515=IPI, GO:0005667=IC, GO:0006355=ISS, GO:0000790=IDA, GO:0003700=NAS, GO:0044212=IDA, GO:0003705=TAS, GO:0005634=IC, GO:0072560=IEA, GO:0003677=TAS, GO:0006351=IEA, GO:0060287=ISS, GO:0042384=ISS, GO:0050796=ISS, GO:0031018=ISS, GO:0045944=ISS, GO:0060285=ISS, GO:2000078=ISS, GO:0048469=ISS, GO:0045893=IDA, GO:0045892=IDA} cell maturation, ciliary cell motility, cilium assembly, endocrine pancreas development, epithelial cilium movement involved in determination of left/right asymmetry, negative regulation of transcription, DNA-dependent, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of type B pancreatic cell development, regulation of insulin secretion, regulation of transcription, DNA-dependent, transcription, DNA-dependent, type B pancreatic cell maturation nuclear chromatin, nucleus, transcription factor complex DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, protein binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding Human UniProtKB:P48381 RFX4 UniProtKB UniProtKB {GO:0006355=GO_REF:0000002, GO:0045944=GO_REF:0000019, GO:0021696=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0030901=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0030900=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0021516=GO_REF:0000019} Q33E94 Transcription factor RFX4 protein 20130413 {GO:0006355=IEA, GO:0045944=IEA, GO:0021696=IEA, GO:0003682=IEA, GO:0030901=IEA, GO:0005634=IEA, GO:0030900=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0021516=IEA} cerebellar cortex morphogenesis, dorsal spinal cord development, forebrain development, midbrain development, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, chromatin binding Human UniProtKB-SubCell:SL-0191 RFX5 IntAct UniProtKB {GO:0005515=PMID:16464847, GO:0006355=GO_REF:0000002, GO:0003700=PMID:9806546, GO:0005634=GO_REF:0000039, GO:0000122=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P48382 DNA-binding protein RFX5 protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0003700=NAS, GO:0005634=IEA, GO:0000122=IEA, GO:0003677=IEA, GO:0006351=IEA} negative regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, protein binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:Q92769 RFX6 UniProtKB UniProtKB {GO:0005515=PMID:20148032, GO:0003309=GO_REF:0000024, GO:0050796=PMID:20148032, GO:0044212=PMID:20148032, GO:0031018=PMID:20148032, GO:0003311=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0003310=GO_REF:0000024, GO:0042593=PMID:20148032, GO:0045893=PMID:20148032, GO:0090104=GO_REF:0000024, GO:0006351=GO_REF:0000037} Q8HWS3 DNA-binding protein RFX6 protein 20100219 {GO:0005515=IPI, GO:0003309=ISS, GO:0050796=IMP, GO:0044212=IDA, GO:0031018=IMP, GO:0003311=ISS, GO:0005634=ISS, GO:0003310=ISS, GO:0042593=IMP, GO:0045893=IDA, GO:0090104=ISS, GO:0006351=IEA} endocrine pancreas development, glucose homeostasis, pancreatic A cell differentiation, pancreatic D cell differentiation, pancreatic epsilon cell differentiation, positive regulation of transcription, DNA-dependent, regulation of insulin secretion, transcription, DNA-dependent, type B pancreatic cell differentiation nucleus protein binding, transcription regulatory region DNA binding Human UniProtKB:Q8C7R7 RFXANK PINC UniProtKB {GO:0003712=PMID:10072068, GO:0005737=GO_REF:0000019, GO:0003700=PMID:9806546, GO:0042826=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0007265=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O14593 DNA-binding protein RFXANK protein 20040811 {GO:0003712=TAS, GO:0005737=IEA, GO:0003700=NAS, GO:0042826=IEA, GO:0045944=IEA, GO:0007265=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} Ras protein signal transduction, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, nucleus DNA binding, histone deacetylase binding, sequence-specific DNA binding transcription factor activity, transcription cofactor activity Human RFXAP PINC UniProtKB {GO:0003700=PMID:9118943, GO:0003713=PMID:9118943, GO:0005634=GO_REF:0000039, GO:0045893=GO_REF:0000019, GO:0003677=GO_REF:0000019} O00287 Regulatory factor X-associated protein protein 20030904 {GO:0003700=NAS, GO:0003713=TAS, GO:0005634=IEA, GO:0045893=IEA, GO:0003677=IEA} positive regulation of transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity Human RGAG1 null null {} null null null null {} null null null RGAG4 null null {} null null null null {} null null null RGL1 Reactome UniProtKB {GO:0005085=GO_REF:0000038, GO:0005622=GO_REF:0000002, GO:0051056=GO_REF:0000002, GO:0008321=PMID:10760592, GO:0007264=PMID:10760592, GO:0044281=Reactome:REACT_111217, GO:0005575=GO_REF:0000015, GO:0044255=Reactome:REACT_22279, GO:0005829=Reactome:REACT_115625} Q9NZL6 Ral guanine nucleotide dissociation stimulator-like 1 protein 20130301 {GO:0005085=IEA, GO:0005622=IEA, GO:0051056=IEA, GO:0008321=NAS, GO:0007264=NAS, GO:0044281=TAS, GO:0005575=ND, GO:0044255=TAS, GO:0005829=TAS} cellular lipid metabolic process, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction, small molecule metabolic process cellular_component, cytosol, intracellular Ral guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity Human RGL2 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0005085=GO_REF:0000038, GO:0051056=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0007265=PMID:8976381, GO:0005575=GO_REF:0000015, GO:0005088=PMID:8976381} O15211 Ral guanine nucleotide dissociation stimulator-like 2 protein 20061026 {GO:0005622=IEA, GO:0005085=IEA, GO:0051056=IEA, GO:0007264=IEA, GO:0007265=NAS, GO:0005575=ND, GO:0005088=NAS} Ras protein signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cellular_component, intracellular Ras guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity Human RGL3 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0005085=GO_REF:0000037, GO:0051056=GO_REF:0000002, GO:0007264=GO_REF:0000002} Q3MIN7 Ral guanine nucleotide dissociation stimulator-like 3 protein 20130413 {GO:0005622=IEA, GO:0005085=IEA, GO:0051056=IEA, GO:0007264=IEA} regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction intracellular guanyl-nucleotide exchange factor activity Human UniProtKB-KW:KW-0344 RGL4 UniProtKB UniProtKB {GO:0005085=GO_REF:0000037, GO:0005622=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0016023=GO_REF:0000039} Q8IZJ4 Ral-GDS-related protein protein 20130413 {GO:0005085=IEA, GO:0005622=IEA, GO:0007264=IEA, GO:0016023=IEA} small GTPase mediated signal transduction cytoplasmic membrane-bounded vesicle, intracellular guanyl-nucleotide exchange factor activity Human UniProtKB-SubCell:SL-0088 RGMA LIFEdb UniProtKB {GO:0005886=GO_REF:0000039, GO:0009986=GO_REF:0000019, GO:0005783=GO_REF:0000054, GO:0007411=Reactome:REACT_18266, GO:0001843=GO_REF:0000019, GO:0031225=GO_REF:0000037, GO:0030509=GO_REF:0000019, GO:0030510=GO_REF:0000019, GO:0015026=GO_REF:0000019} Q96B86 Repulsive guidance molecule A protein 20100607 {GO:0005886=IEA, GO:0009986=IEA, GO:0005783=IDA, GO:0007411=TAS, GO:0001843=IEA, GO:0031225=IEA, GO:0030509=IEA, GO:0030510=IEA, GO:0015026=IEA} BMP signaling pathway, axon guidance, neural tube closure, regulation of BMP signaling pathway anchored to membrane, cell surface, endoplasmic reticulum, plasma membrane coreceptor activity Human RGN UniProtKB UniProtKB {GO:0050848=GO_REF:0000024, GO:0004341=PMID:20329768, GO:0005737=GO_REF:0000024, GO:0005509=PMID:20329768, GO:0006874=GO_REF:0000024, GO:0008270=PMID:20329768, GO:0005634=GO_REF:0000024, GO:0030234=GO_REF:0000002, GO:0032781=GO_REF:0000024} Q15493 Regucalcin protein 20101215 {GO:0050848=ISS, GO:0004341=IDA, GO:0005737=ISS, GO:0005509=IDA, GO:0006874=ISS, GO:0008270=IDA, GO:0005634=ISS, GO:0030234=IEA, GO:0032781=ISS} cellular calcium ion homeostasis, positive regulation of ATPase activity, regulation of calcium-mediated signaling cytoplasm, nucleus calcium ion binding, enzyme regulator activity, gluconolactonase activity, zinc ion binding Human RGP1 null null {} null null null null {} null null null RGPD1 InterPro UniProtKB {GO:0046907=GO_REF:0000002, GO:0000042=GO_REF:0000002} P0DJD0 RANBP2-like and GRIP domain-containing protein 1 protein 20130413 {GO:0046907=IEA, GO:0000042=IEA} intracellular transport, protein targeting to Golgi Human InterPro:IPR000237 RGPD2 InterPro UniProtKB {GO:0000042=GO_REF:0000002} P0DJD1 RANBP2-like and GRIP domain-containing protein 2 protein 20130413 {GO:0000042=IEA} protein targeting to Golgi Human InterPro:IPR000237 RGPD3 InterPro UniProtKB {GO:0000042=GO_REF:0000002} J3KNE0 RanBP2-like and GRIP domain-containing protein 3 protein 20130413 {GO:0000042=IEA} protein targeting to Golgi Human InterPro:IPR000237 RGPD4 InterPro UniProtKB {GO:0000042=GO_REF:0000002} Q7Z3J3 RanBP2-like and GRIP domain-containing protein 4 protein 20130413 {GO:0000042=IEA} protein targeting to Golgi Human InterPro:IPR000237 RGPD5 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0000042=GO_REF:0000002} Q99666 RANBP2-like and GRIP domain-containing protein 5/6 protein 20130413 {GO:0005737=IEA, GO:0000042=IEA} protein targeting to Golgi cytoplasm Human UniProtKB-SubCell:SL-0086 RGPD6 null null {} null null null null {} null null null RGPD8 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0005643=PMID:9480752, GO:0008536=PMID:9480752, GO:0000042=GO_REF:0000002} O14715 RANBP2-like and GRIP domain-containing protein 8 protein 20061026 {GO:0008150=ND, GO:0005643=NAS, GO:0008536=NAS, GO:0000042=IEA} biological_process, protein targeting to Golgi nuclear pore Ran GTPase binding Human RGR IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0018298=GO_REF:0000037, GO:0009881=GO_REF:0000037, GO:0007186=PMID:8641686, GO:0006935=GO_REF:0000002, GO:0004930=PMID:8641686, GO:0005887=GO_REF:0000019, GO:0004950=GO_REF:0000002, GO:0007602=GO_REF:0000037, GO:0007601=GO_REF:0000037} P47804 RPE-retinal G protein-coupled receptor protein 20130415 {GO:0005515=IPI, GO:0018298=IEA, GO:0009881=IEA, GO:0007186=TAS, GO:0006935=IEA, GO:0004930=TAS, GO:0005887=IEA, GO:0004950=IEA, GO:0007602=IEA, GO:0007601=IEA} G-protein coupled receptor signaling pathway, chemotaxis, phototransduction, protein-chromophore linkage, visual perception integral to plasma membrane G-protein coupled receptor activity, chemokine receptor activity, photoreceptor activity, protein binding Human UniProtKB:Q96EK5 RGS1 GOC UniProtKB {GO:0043547=PMID:10747990, GO:0007165=PMID:8241276, GO:0005516=PMID:10747990, GO:0006955=PMID:8241276, GO:0005737=GO_REF:0000033, GO:0005886=GO_REF:0000033, GO:0038032=GO_REF:0000002, GO:0007193=PMID:10480894, GO:0005096=GO_REF:0000033} Q08116 Regulator of G-protein signaling 1 protein 20130413 {GO:0043547=TAS, GO:0007165=NAS, GO:0005516=TAS, GO:0006955=TAS, GO:0005737=IBA, GO:0005886=IBA, GO:0038032=IEA, GO:0007193=TAS, GO:0005096=IBA} adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, immune response, positive regulation of GTPase activity, signal transduction, termination of G-protein coupled receptor signaling pathway cytoplasm, plasma membrane GTPase activator activity, calmodulin binding Human RGS10 GOC UniProtKB {GO:0043547=GO_REF:0000033, GO:0005737=GO_REF:0000033, GO:0005886=GO_REF:0000033, GO:0043197=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0043025=GO_REF:0000019, GO:0038032=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0043679=GO_REF:0000019, GO:0005096=GO_REF:0000033} O43665 Regulator of G-protein signaling 10 protein 20130413 {GO:0043547=IBA, GO:0005737=IBA, GO:0005886=IBA, GO:0043197=IEA, GO:0005730=IDA, GO:0043025=IEA, GO:0038032=IEA, GO:0005634=IDA, GO:0043679=IEA, GO:0005096=IBA} positive regulation of GTPase activity, termination of G-protein coupled receptor signaling pathway axon terminus, cytoplasm, dendritic spine, neuronal cell body, nucleolus, nucleus, plasma membrane GTPase activator activity Human PANTHER:PTN000090250 RGS11 ENSEMBL UniProtKB {GO:0043547=PMID:9789084, GO:0035556=GO_REF:0000002, GO:0043234=PMID:18468998, GO:0005737=GO_REF:0000033, GO:0008277=PMID:9789084, GO:0005886=GO_REF:0000033, GO:0007186=GO_REF:0000002, GO:0005834=GO_REF:0000002, GO:0044292=GO_REF:0000019, GO:0038032=GO_REF:0000002, GO:0004871=GO_REF:0000002, GO:0005096=GO_REF:0000033} Q4TT72 Regulator of G-protein signalling 11, isoform CRA_a protein 20130413 {GO:0043547=TAS, GO:0035556=IEA, GO:0043234=IDA, GO:0005737=IBA, GO:0008277=TAS, GO:0005886=IBA, GO:0007186=IEA, GO:0005834=IEA, GO:0044292=IEA, GO:0038032=IEA, GO:0004871=IEA, GO:0005096=IBA} G-protein coupled receptor signaling pathway, intracellular signal transduction, positive regulation of GTPase activity, regulation of G-protein coupled receptor protein signaling pathway, termination of G-protein coupled receptor signaling pathway cytoplasm, dendrite terminus, heterotrimeric G-protein complex, plasma membrane, protein complex GTPase activator activity, signal transducer activity Human Ensembl:ENSMUSP00000025020 RGS12 InterPro UniProtKB {GO:0043547=PMID:9651375, GO:0000794=PMID:10869340, GO:0005737=GO_REF:0000033, GO:0008277=PMID:9651375, GO:0005886=GO_REF:0000033, GO:0038032=GO_REF:0000002, GO:0005057=GO_REF:0000002, GO:0030695=PMID:9651375, GO:0005096=GO_REF:0000033} Q8WX95 RGS12TS-S isoform protein 20130413 {GO:0043547=TAS, GO:0000794=TAS, GO:0005737=IBA, GO:0008277=TAS, GO:0005886=IBA, GO:0038032=IEA, GO:0005057=IEA, GO:0030695=IDA, GO:0005096=IBA} positive regulation of GTPase activity, regulation of G-protein coupled receptor protein signaling pathway, termination of G-protein coupled receptor signaling pathway condensed nuclear chromosome, cytoplasm, plasma membrane GTPase activator activity, GTPase regulator activity, receptor signaling protein activity Human InterPro:IPR000342|InterPro:IPR016137 RGS13 GOC UniProtKB {GO:0043547=GO_REF:0000033, GO:0005737=GO_REF:0000033, GO:0005886=GO_REF:0000033, GO:0007186=GO_REF:0000019, GO:0038032=GO_REF:0000002, GO:0005634=GO_REF:0000019, GO:0005096=GO_REF:0000033, GO:0005829=GO_REF:0000019} O14921 Regulator of G-protein signaling 13 protein 20130413 {GO:0043547=IBA, GO:0005737=IBA, GO:0005886=IBA, GO:0007186=IEA, GO:0038032=IEA, GO:0005634=IEA, GO:0005096=IBA, GO:0005829=IEA} G-protein coupled receptor signaling pathway, positive regulation of GTPase activity, termination of G-protein coupled receptor signaling pathway cytoplasm, cytosol, nucleus, plasma membrane GTPase activator activity Human PANTHER:PTN000090250 RGS14 GOC UniProtKB {GO:0008017=PMID:15917656, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000024, GO:0030159=GO_REF:0000024, GO:0038032=GO_REF:0000002, GO:0060291=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0043620=GO_REF:0000024, GO:0030425=GO_REF:0000024, GO:0031914=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0007059=GO_REF:0000024, GO:0043197=GO_REF:0000024, GO:0050769=GO_REF:0000024, GO:0043407=GO_REF:0000024, GO:0045211=GO_REF:0000037, GO:0070373=GO_REF:0000024, GO:0007612=GO_REF:0000024, GO:0045111=GO_REF:0000052, GO:0007051=PMID:15917656, GO:0006979=GO_REF:0000024, GO:0030695=GO_REF:0000002, GO:0005813=GO_REF:0000024, GO:0007616=GO_REF:0000024, GO:0019901=GO_REF:0000019, GO:0005874=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005819=PMID:15917656, GO:0014069=GO_REF:0000024, GO:0010070=GO_REF:0000024, GO:0006913=GO_REF:0000024, GO:0043547=PMID:9168931, GO:0032794=GO_REF:0000019, GO:0016604=GO_REF:0000024, GO:0000922=GO_REF:0000024, GO:0007067=GO_REF:0000019, GO:0008277=PMID:9168931, GO:0016605=GO_REF:0000039, GO:0008542=GO_REF:0000024, GO:0005092=PMID:15917656, GO:0048008=GO_REF:0000024, GO:0005057=GO_REF:0000024, GO:0005096=PMID:15917656, GO:0051301=PMID:17635935} O43566 Regulator of G-protein signaling 14 protein 20130413 {GO:0008017=IDA, GO:0030054=IEA, GO:0005886=ISS, GO:0030159=ISS, GO:0038032=IEA, GO:0060291=ISS, GO:0005634=IDA, GO:0043620=ISS, GO:0030425=ISS, GO:0031914=ISS, GO:0005737=ISS, GO:0007059=ISS, GO:0043197=ISS, GO:0050769=ISS, GO:0043407=ISS, GO:0045211=IEA, GO:0070373=ISS, GO:0007612=ISS, GO:0045111=IDA, GO:0007051=IMP, GO:0006979=ISS, GO:0030695=IEA, GO:0005813=ISS, GO:0007616=ISS, GO:0019901=IEA, GO:0005874=IEA, GO:0005730=IDA, GO:0005819=IDA, GO:0014069=ISS, GO:0010070=ISS, GO:0006913=ISS, GO:0043547=TAS, GO:0032794=IEA, GO:0016604=ISS, GO:0000922=ISS, GO:0007067=IEA, GO:0008277=TAS, GO:0016605=IEA, GO:0008542=ISS, GO:0005092=IDA, GO:0048008=ISS, GO:0005057=ISS, GO:0005096=IDA, GO:0051301=IMP} cell division, chromosome segregation, learning, long-term memory, long-term synaptic potentiation, mitosis, negative regulation of ERK1 and ERK2 cascade, negative regulation of MAP kinase activity, negative regulation of synaptic plasticity, nucleocytoplasmic transport, platelet-derived growth factor receptor signaling pathway, positive regulation of GTPase activity, positive regulation of neurogenesis, regulation of DNA-dependent transcription in response to stress, regulation of G-protein coupled receptor protein signaling pathway, response to oxidative stress, spindle organization, termination of G-protein coupled receptor signaling pathway, visual learning, zygote asymmetric cell division PML body, cell junction, centrosome, cytoplasm, dendrite, dendritic spine, intermediate filament cytoskeleton, microtubule, nuclear body, nucleolus, nucleus, plasma membrane, postsynaptic density, postsynaptic membrane, spindle, spindle pole GDP-dissociation inhibitor activity, GTPase activating protein binding, GTPase activator activity, GTPase regulator activity, microtubule binding, protein kinase binding, receptor signaling complex scaffold activity, receptor signaling protein activity Human RGS16 GOC UniProtKB {GO:0043547=PMID:10747990, GO:0005515=PMID:21784977, GO:0005516=PMID:10747990, GO:0005737=GO_REF:0000033, GO:0008277=PMID:10747990, GO:0005886=GO_REF:0000033, GO:0038032=GO_REF:0000002, GO:0007601=PMID:9469939, GO:0005096=GO_REF:0000033} O15492 Regulator of G-protein signaling 16 protein 20130413 {GO:0043547=TAS, GO:0005515=IPI, GO:0005516=TAS, GO:0005737=IBA, GO:0008277=TAS, GO:0005886=IBA, GO:0038032=IEA, GO:0007601=TAS, GO:0005096=IBA} positive regulation of GTPase activity, regulation of G-protein coupled receptor protein signaling pathway, termination of G-protein coupled receptor signaling pathway, visual perception cytoplasm, plasma membrane GTPase activator activity, calmodulin binding, protein binding Human RGS17 GOC UniProtKB {GO:0043547=GO_REF:0000033, GO:0005737=GO_REF:0000033, GO:0005886=GO_REF:0000033, GO:0038032=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0005096=GO_REF:0000033} Q9UGC6 Regulator of G-protein signaling 17 protein 20130413 {GO:0043547=IBA, GO:0005737=IBA, GO:0005886=IBA, GO:0038032=IEA, GO:0005634=IEA, GO:0005096=IBA} positive regulation of GTPase activity, termination of G-protein coupled receptor signaling pathway cytoplasm, nucleus, plasma membrane GTPase activator activity Human PANTHER:PTN000090250 RGS18 RefGenome UniProtKB {GO:0005737=GO_REF:0000033, GO:0005886=GO_REF:0000033, GO:0007186=GO_REF:0000019, GO:0038032=GO_REF:0000002, GO:0005096=GO_REF:0000033} Q9NS28 Regulator of G-protein signaling 18 protein 20100903 {GO:0005737=IBA, GO:0005886=IBA, GO:0007186=IEA, GO:0038032=IEA, GO:0005096=IBA} G-protein coupled receptor signaling pathway, termination of G-protein coupled receptor signaling pathway cytoplasm, plasma membrane GTPase activator activity Human PANTHER:PTN000090250 RGS19 GOC UniProtKB {GO:0005515=PMID:8524874, GO:0005794=PMID:9571244, GO:0005886=GO_REF:0000033, GO:0007264=PMID:9571244, GO:0030136=GO_REF:0000019, GO:0005834=PMID:8524874, GO:0006914=GO_REF:0000037, GO:0038032=GO_REF:0000002, GO:0043547=GO_REF:0000033, GO:0005903=GO_REF:0000019, GO:0044445=GO_REF:0000019, GO:0001965=GO_REF:0000019, GO:0005737=GO_REF:0000033, GO:0016020=PMID:9571244, GO:0007186=PMID:8524874, GO:0005096=GO_REF:0000033} P49795 Regulator of G-protein signaling 19 protein 20130413 {GO:0005515=IPI, GO:0005794=TAS, GO:0005886=IBA, GO:0007264=TAS, GO:0030136=IEA, GO:0005834=TAS, GO:0006914=IEA, GO:0038032=IEA, GO:0043547=IBA, GO:0005903=IEA, GO:0044445=IEA, GO:0001965=IEA, GO:0005737=IBA, GO:0016020=TAS, GO:0007186=TAS, GO:0005096=IBA} G-protein coupled receptor signaling pathway, autophagy, positive regulation of GTPase activity, small GTPase mediated signal transduction, termination of G-protein coupled receptor signaling pathway Golgi apparatus, brush border, clathrin-coated vesicle, cytoplasm, cytosolic part, heterotrimeric G-protein complex, membrane, plasma membrane G-protein alpha-subunit binding, GTPase activator activity, protein binding Human PANTHER:PTN000090250 RGS2 GOC UniProtKB {GO:0005515=PMID:14608379, GO:0005516=PMID:10747990, GO:0045744=GO_REF:0000024, GO:0005886=GO_REF:0000033, GO:0005730=GO_REF:0000039, GO:0038032=GO_REF:0000002, GO:0007283=GO_REF:0000019, GO:0010519=GO_REF:0000024, GO:0006417=GO_REF:0000037, GO:0005829=GO_REF:0000024, GO:0060087=GO_REF:0000019, GO:0043547=PMID:10747990, GO:0005739=GO_REF:0000039, GO:0010614=GO_REF:0000024, GO:0007049=GO_REF:0000037, GO:0005737=GO_REF:0000033, GO:0008277=PMID:10747990, GO:0060452=GO_REF:0000024, GO:0050873=GO_REF:0000019, GO:0043407=GO_REF:0000024, GO:0009898=GO_REF:0000024, GO:0055119=GO_REF:0000024, GO:0071877=GO_REF:0000024, GO:0005096=GO_REF:0000033} P41220 Regulator of G-protein signaling 2 protein 20130413 {GO:0005515=IPI, GO:0005516=TAS, GO:0045744=ISS, GO:0005886=IBA, GO:0005730=IEA, GO:0038032=IEA, GO:0007283=IEA, GO:0010519=ISS, GO:0006417=IEA, GO:0005829=ISS, GO:0060087=IEA, GO:0043547=TAS, GO:0005739=IEA, GO:0010614=ISS, GO:0007049=IEA, GO:0005737=IBA, GO:0008277=TAS, GO:0060452=ISS, GO:0050873=IEA, GO:0043407=ISS, GO:0009898=ISS, GO:0055119=ISS, GO:0071877=ISS, GO:0005096=IBA} brown fat cell differentiation, cell cycle, negative regulation of G-protein coupled receptor protein signaling pathway, negative regulation of MAP kinase activity, negative regulation of cardiac muscle hypertrophy, negative regulation of phospholipase activity, positive regulation of GTPase activity, positive regulation of cardiac muscle contraction, regulation of G-protein coupled receptor protein signaling pathway, regulation of adrenergic receptor signaling pathway, regulation of translation, relaxation of cardiac muscle, relaxation of vascular smooth muscle, spermatogenesis, termination of G-protein coupled receptor signaling pathway cytoplasm, cytosol, internal side of plasma membrane, mitochondrion, nucleolus, plasma membrane GTPase activator activity, calmodulin binding, protein binding Human RGS20 GOC UniProtKB {GO:0043547=PMID:9748279, GO:0005737=GO_REF:0000033, GO:0008277=PMID:9748279, GO:0005886=GO_REF:0000033, GO:0038032=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0005096=GO_REF:0000033} O76081 Regulator of G-protein signaling 20 protein 20130413 {GO:0043547=TAS, GO:0005737=IBA, GO:0008277=TAS, GO:0005886=IBA, GO:0038032=IEA, GO:0005634=IEA, GO:0005096=IBA} positive regulation of GTPase activity, regulation of G-protein coupled receptor protein signaling pathway, termination of G-protein coupled receptor signaling pathway cytoplasm, nucleus, plasma membrane GTPase activator activity Human RGS3 InterPro UniProtKB {GO:0043547=PMID:9858594, GO:0000188=PMID:8602223, GO:0005737=GO_REF:0000033, GO:0008277=PMID:9858594, GO:0005886=GO_REF:0000033, GO:0038032=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0005829=PMID:9858594, GO:0005096=GO_REF:0000033} Q5VZ06 Regulator of G-protein-signaling 3 protein 20130413 {GO:0043547=TAS, GO:0000188=TAS, GO:0005737=IBA, GO:0008277=TAS, GO:0005886=IBA, GO:0038032=IEA, GO:0005634=IEA, GO:0005829=TAS, GO:0005096=IBA} inactivation of MAPK activity, positive regulation of GTPase activity, regulation of G-protein coupled receptor protein signaling pathway, termination of G-protein coupled receptor signaling pathway cytoplasm, cytosol, nucleus, plasma membrane GTPase activator activity Human InterPro:IPR000342|InterPro:IPR016137 RGS4 GOC UniProtKB {GO:0043547=PMID:10747990, GO:0000188=PMID:8602223, GO:0005516=PMID:10747990, GO:0005737=GO_REF:0000033, GO:0008277=PMID:10747990, GO:0005886=GO_REF:0000033, GO:0016020=GO_REF:0000019, GO:0038032=GO_REF:0000002, GO:0005096=GO_REF:0000033, GO:0005829=GO_REF:0000019} P49798 Regulator of G-protein signaling 4 protein 20130413 {GO:0043547=TAS, GO:0000188=TAS, GO:0005516=TAS, GO:0005737=IBA, GO:0008277=TAS, GO:0005886=IBA, GO:0016020=IEA, GO:0038032=IEA, GO:0005096=IBA, GO:0005829=IEA} inactivation of MAPK activity, positive regulation of GTPase activity, regulation of G-protein coupled receptor protein signaling pathway, termination of G-protein coupled receptor signaling pathway cytoplasm, cytosol, membrane, plasma membrane GTPase activator activity, calmodulin binding Human RGS5 GOC UniProtKB {GO:0043547=PMID:10471929, GO:0007165=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0008277=PMID:10471929, GO:0005886=GO_REF:0000033, GO:0038032=GO_REF:0000002, GO:0005096=GO_REF:0000033} O15539 Regulator of G-protein signaling 5 protein 20130413 {GO:0043547=TAS, GO:0007165=IEA, GO:0005737=IDA, GO:0008277=TAS, GO:0005886=IBA, GO:0038032=IEA, GO:0005096=IBA} positive regulation of GTPase activity, regulation of G-protein coupled receptor protein signaling pathway, signal transduction, termination of G-protein coupled receptor signaling pathway cytoplasm, plasma membrane GTPase activator activity Human RGS6 InterPro UniProtKB {GO:0043547=PMID:10083744, GO:0005515=PMID:22939624, GO:0035556=GO_REF:0000002, GO:0005737=GO_REF:0000033, GO:0008277=GO_REF:0000029, GO:0005886=GO_REF:0000033, GO:0007186=GO_REF:0000002, GO:0045666=GO_REF:0000019, GO:0005834=GO_REF:0000002, GO:0038032=GO_REF:0000002, GO:0004871=GO_REF:0000002, GO:0005096=GO_REF:0000033} Q7Z4K6 RGS6 protein n isoform protein 20130413 {GO:0043547=TAS, GO:0005515=IPI, GO:0035556=IEA, GO:0005737=IBA, GO:0008277=NAS, GO:0005886=IBA, GO:0007186=IEA, GO:0045666=IEA, GO:0005834=IEA, GO:0038032=IEA, GO:0004871=IEA, GO:0005096=IBA} G-protein coupled receptor signaling pathway, intracellular signal transduction, positive regulation of GTPase activity, positive regulation of neuron differentiation, regulation of G-protein coupled receptor protein signaling pathway, termination of G-protein coupled receptor signaling pathway cytoplasm, heterotrimeric G-protein complex, plasma membrane GTPase activator activity, protein binding, signal transducer activity Human InterPro:IPR000342|InterPro:IPR016137 RGS7 InterPro UniProtKB {GO:0031681=GO_REF:0000019, GO:0005886=GO_REF:0000033, GO:0005834=GO_REF:0000002, GO:0038032=GO_REF:0000002, GO:0044292=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0043547=GO_REF:0000033, GO:0035556=GO_REF:0000002, GO:0005737=GO_REF:0000033, GO:0008277=GO_REF:0000029, GO:0007186=GO_REF:0000002, GO:0004871=GO_REF:0000002, GO:0005096=GO_REF:0000033} Q5T3H5 Regulator of G-protein-signaling 7 protein 20130413 {GO:0031681=IEA, GO:0005886=IBA, GO:0005834=IEA, GO:0038032=IEA, GO:0044292=IEA, GO:0005634=IEA, GO:0005829=IEA, GO:0043547=IBA, GO:0035556=IEA, GO:0005737=IBA, GO:0008277=NAS, GO:0007186=IEA, GO:0004871=IEA, GO:0005096=IBA} G-protein coupled receptor signaling pathway, intracellular signal transduction, positive regulation of GTPase activity, regulation of G-protein coupled receptor protein signaling pathway, termination of G-protein coupled receptor signaling pathway cytoplasm, cytosol, dendrite terminus, heterotrimeric G-protein complex, nucleus, plasma membrane G-protein beta-subunit binding, GTPase activator activity, signal transducer activity Human InterPro:IPR000342|InterPro:IPR016137 RGS7BP UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0007186=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0009968=GO_REF:0000037} Q6MZT1 Regulator of G-protein signaling 7-binding protein protein 20130413 {GO:0005737=IEA, GO:0005886=IEA, GO:0007186=IEA, GO:0005634=IEA, GO:0009968=IEA} G-protein coupled receptor signaling pathway, negative regulation of signal transduction cytoplasm, nucleus, plasma membrane Human UniProtKB-SubCell:SL-0039 RGS9 PINC UniProtKB {GO:0043627=GO_REF:0000019, GO:0005886=GO_REF:0000033, GO:0005834=GO_REF:0000002, GO:0038032=GO_REF:0000002, GO:0005634=GO_REF:0000019, GO:0007212=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0007399=GO_REF:0000019, GO:0035556=GO_REF:0000002, GO:0005737=GO_REF:0000033, GO:0008277=PMID:9765512, GO:0007186=GO_REF:0000002, GO:0004871=GO_REF:0000002, GO:0007601=GO_REF:0000037, GO:0005096=GO_REF:0000033} O75916 Regulator of G-protein signaling 9 protein 20030904 {GO:0043627=IEA, GO:0005886=IBA, GO:0005834=IEA, GO:0038032=IEA, GO:0005634=IEA, GO:0007212=IEA, GO:0032403=IEA, GO:0007399=IEA, GO:0035556=IEA, GO:0005737=IBA, GO:0008277=TAS, GO:0007186=IEA, GO:0004871=IEA, GO:0007601=IEA, GO:0005096=IBA} G-protein coupled receptor signaling pathway, dopamine receptor signaling pathway, intracellular signal transduction, nervous system development, regulation of G-protein coupled receptor protein signaling pathway, response to estrogen stimulus, termination of G-protein coupled receptor signaling pathway, visual perception cytoplasm, heterotrimeric G-protein complex, nucleus, plasma membrane GTPase activator activity, protein complex binding, signal transducer activity Human RGS9BP ENSEMBL UniProtKB {GO:0050908=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0009968=GO_REF:0000037} Q6ZS82 Regulator of G-protein signaling 9-binding protein protein 20130413 {GO:0050908=IEA, GO:0016021=IEA, GO:0009968=IEA} detection of light stimulus involved in visual perception, negative regulation of signal transduction integral to membrane Human Ensembl:ENSMUSP00000065511 RGSL1 InterPro UniProtKB {GO:0038032=GO_REF:0000002, GO:0016021=GO_REF:0000037} H3BU64 Regulator of G-protein-signaling protein-like protein 20130413 {GO:0038032=IEA, GO:0016021=IEA} termination of G-protein coupled receptor signaling pathway integral to membrane Human InterPro:IPR000342|InterPro:IPR016137 RHAG GOC UniProtKB {GO:0005886=Reactome:REACT_121236, GO:0005887=PMID:1417776, GO:0015696=PMID:19273840, GO:0072488=PMID:17712059, GO:0051739=PMID:19273840, GO:0030506=PMID:16580865, GO:0015701=Reactome:REACT_121380, GO:0006873=PMID:15856280, GO:0008519=PMID:16866382, GO:0044281=Reactome:REACT_111217, GO:0015670=PMID:19273840, GO:0055085=Reactome:REACT_19118} Q02094 Ammonium transporter Rh type A protein 20130413 {GO:0005886=TAS, GO:0005887=TAS, GO:0015696=IDA, GO:0072488=IDA, GO:0051739=IDA, GO:0030506=IPI, GO:0015701=TAS, GO:0006873=IDA, GO:0008519=IDA, GO:0044281=TAS, GO:0015670=IDA, GO:0055085=TAS} ammonium transmembrane transport, ammonium transport, bicarbonate transport, carbon dioxide transport, cellular ion homeostasis, small molecule metabolic process, transmembrane transport integral to plasma membrane, plasma membrane ammonia transmembrane transporter activity, ammonium transmembrane transporter activity, ankyrin binding Human RHBDD1 UniProtKB UniProtKB {GO:0043066=GO_REF:0000024, GO:0004252=GO_REF:0000002, GO:0031293=GO_REF:0000024, GO:0048515=GO_REF:0000024, GO:0006915=GO_REF:0000037, GO:0030176=GO_REF:0000024, GO:0044322=GO_REF:0000024, GO:0030433=GO_REF:0000024, GO:0005739=GO_REF:0000039, GO:2000254=GO_REF:0000024, GO:0034644=GO_REF:0000024, GO:0010954=GO_REF:0000024, GO:0005789=GO_REF:0000024, GO:0034620=GO_REF:0000024, GO:0043687=GO_REF:0000024} Q8TEB9 Rhomboid-related protein 4 protein 20120706 {GO:0043066=ISS, GO:0004252=IEA, GO:0031293=ISS, GO:0048515=ISS, GO:0006915=IEA, GO:0030176=ISS, GO:0044322=ISS, GO:0030433=ISS, GO:0005739=IEA, GO:2000254=ISS, GO:0034644=ISS, GO:0010954=ISS, GO:0005789=ISS, GO:0034620=ISS, GO:0043687=ISS} ER-associated protein catabolic process, apoptotic process, cellular response to UV, cellular response to unfolded protein, membrane protein intracellular domain proteolysis, negative regulation of apoptotic process, positive regulation of protein processing, post-translational protein modification, regulation of male germ cell proliferation, spermatid differentiation endoplasmic reticulum membrane, endoplasmic reticulum quality control compartment, integral to endoplasmic reticulum membrane, mitochondrion serine-type endopeptidase activity NOT Human UniProtKB:Q8BHC7 RHBDD2 UniProtKB UniProtKB {GO:0004252=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q6NTF9 Rhomboid domain-containing protein 2 protein 20130413 {GO:0004252=IEA, GO:0016021=IEA} integral to membrane serine-type endopeptidase activity Human UniProtKB-KW:KW-0812 RHBDD3 UniProtKB UniProtKB {GO:0004252=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q9Y3P4 Rhomboid domain-containing protein 3 protein 20130413 {GO:0004252=IEA, GO:0016021=IEA} integral to membrane serine-type endopeptidase activity Human UniProtKB-KW:KW-0812 RHBDF1 UniProtKB UniProtKB {GO:0004252=PMID:21439629, GO:0008283=PMID:18832597, GO:0015031=GO_REF:0000037, GO:0042058=PMID:18832597, GO:0019838=GO_REF:0000037, GO:0000139=PMID:18832597, GO:0016477=PMID:18832597, GO:0061136=PMID:21439629, GO:0006508=GO_REF:0000002, GO:0050709=PMID:21439629, GO:0005789=PMID:18832597, GO:0050708=PMID:18832597, GO:0016021=GO_REF:0000037} Q96CC6 Inactive rhomboid protein 1 protein 20110401 {GO:0004252=IDA, GO:0008283=IMP, GO:0015031=IEA, GO:0042058=IMP, GO:0019838=IEA, GO:0000139=IDA, GO:0016477=IMP, GO:0061136=IDA, GO:0006508=IEA, GO:0050709=IDA, GO:0005789=IDA, GO:0050708=IMP, GO:0016021=IEA} cell migration, cell proliferation, negative regulation of protein secretion, protein transport, proteolysis, regulation of epidermal growth factor receptor signaling pathway, regulation of proteasomal protein catabolic process, regulation of protein secretion Golgi membrane, endoplasmic reticulum membrane, integral to membrane growth factor binding, serine-type endopeptidase activity Human RHBDF2 UniProtKB UniProtKB {GO:0005886=PMID:22265016, GO:0019838=GO_REF:0000037, GO:0004252=GO_REF:0000002, GO:0005789=GO_REF:0000024, GO:0050709=GO_REF:0000024, GO:0006508=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0015031=GO_REF:0000037} Q6PJF5 Inactive rhomboid protein 2 protein 20120508 {GO:0005886=IDA, GO:0019838=IEA, GO:0004252=IEA, GO:0005789=ISS, GO:0050709=ISS, GO:0006508=IEA, GO:0016021=IEA, GO:0015031=IEA} negative regulation of protein secretion, protein transport, proteolysis endoplasmic reticulum membrane, integral to membrane, plasma membrane growth factor binding, serine-type endopeptidase activity Human RHBDL2 UniProtKB UniProtKB {GO:0005886=PMID:19850051, GO:0004252=PMID:19850051, GO:0006508=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q9NX52 Rhomboid-related protein 2 protein 20110331 {GO:0005886=IDA, GO:0004252=IDA, GO:0006508=IEA, GO:0016021=IEA} proteolysis integral to membrane, plasma membrane serine-type endopeptidase activity Human RHBDL3 InterPro UniProtKB {GO:0004252=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0006508=GO_REF:0000002, GO:0016021=GO_REF:0000002} Q495Y5 RHBDL3 protein protein 20130413 {GO:0004252=IEA, GO:0005509=IEA, GO:0006508=IEA, GO:0016021=IEA} proteolysis integral to membrane calcium ion binding, serine-type endopeptidase activity Human InterPro:IPR002610|InterPro:IPR017213|InterPro:IPR022764 RHBG GOC UniProtKB {GO:0005886=Reactome:REACT_20654, GO:0015696=PMID:18635543, GO:0030506=PMID:15611082, GO:0008519=PMID:15929723, GO:0014731=PMID:18635543, GO:0055085=Reactome:REACT_19118, GO:0016323=PMID:18635543, GO:0005887=PMID:11024028, GO:0072488=PMID:15929723, GO:0051739=PMID:18635543, GO:0070634=PMID:18032481, GO:0016021=GO_REF:0000038, GO:0046658=PMID:15611082, GO:0030659=GO_REF:0000039} Q9H310 Ammonium transporter Rh type B protein 20130413 {GO:0005886=TAS, GO:0015696=IDA, GO:0030506=IPI, GO:0008519=IDA, GO:0014731=IMP, GO:0055085=TAS, GO:0016323=IDA, GO:0005887=IDA, GO:0072488=IDA, GO:0051739=IDA, GO:0070634=IDA, GO:0016021=IEA, GO:0046658=IMP, GO:0030659=IEA} ammonium transmembrane transport, ammonium transport, transepithelial ammonium transport, transmembrane transport anchored to plasma membrane, basolateral plasma membrane, cytoplasmic vesicle membrane, integral to membrane, integral to plasma membrane, plasma membrane, spectrin-associated cytoskeleton ammonia transmembrane transporter activity, ammonium transmembrane transporter activity, ankyrin binding Human RHD UniProtKB UniProtKB {GO:0005887=PMID:1438298, GO:0008519=GO_REF:0000002, GO:0016021=GO_REF:0000038} Q5XLT2 Blood group Rh(D) polypeptide protein 20130413 {GO:0005887=TAS, GO:0008519=IEA, GO:0016021=IEA} integral to membrane, integral to plasma membrane ammonium transmembrane transporter activity Human UniProtKB-KW:KW-0812 RHEB Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0032008=PMID:20381137, GO:0019901=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0007264=GO_REF:0000019, GO:0003924=GO_REF:0000019, GO:0005525=GO_REF:0000024, GO:0030425=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_21261, GO:0007165=PMID:8661031, GO:0016020=PMID:8206940, GO:0043025=GO_REF:0000019, GO:0007050=Reactome:REACT_21387, GO:0005681=GO_REF:0000019, GO:0019003=GO_REF:0000019} Q15382 GTP-binding protein Rheb protein 20080912 {GO:0008286=TAS, GO:0032008=IMP, GO:0019901=IEA, GO:0005886=IEA, GO:0007264=IEA, GO:0003924=IEA, GO:0005525=ISS, GO:0030425=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0007165=TAS, GO:0016020=TAS, GO:0043025=IEA, GO:0007050=TAS, GO:0005681=IEA, GO:0019003=IEA} cell cycle arrest, insulin receptor signaling pathway, positive regulation of TOR signaling cascade, signal transduction, small GTPase mediated signal transduction cytosol, dendrite, membrane, neuronal cell body, plasma membrane, spliceosomal complex GDP binding, GTP binding, GTPase activity, metal ion binding, protein kinase binding Human RHEBL1 UniProtKB UniProtKB {GO:0031929=PMID:12869548, GO:0005737=PMID:16328882, GO:0051092=PMID:16328882, GO:0005886=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0003924=GO_REF:0000002, GO:0005525=PMID:12869548} Q8TAI7 GTPase RhebL1 protein 20090316 {GO:0031929=IMP, GO:0005737=IDA, GO:0051092=IDA, GO:0005886=IEA, GO:0016020=IEA, GO:0007264=IEA, GO:0003924=IEA, GO:0005525=IDA} TOR signaling cascade, positive regulation of NF-kappaB transcription factor activity, small GTPase mediated signal transduction cytoplasm, membrane, plasma membrane GTP binding, GTPase activity Human RHO LIFEdb UniProtKB {GO:0005515=PMID:17693260, GO:0005794=PMID:11767049, GO:0005886=GO_REF:0000054, GO:0007603=Reactome:REACT_160125, GO:0060041=GO_REF:0000019, GO:0004930=GO_REF:0000037, GO:0042622=PMID:19934218, GO:0016918=GO_REF:0000019, GO:0001523=Reactome:REACT_160156, GO:0046872=GO_REF:0000037, GO:0009585=GO_REF:0000019, GO:0001917=PMID:11767049, GO:0018298=GO_REF:0000037, GO:0097381=Reactome:REACT_160286, GO:0009881=GO_REF:0000037, GO:0007186=PMID:2218504, GO:0005887=PMID:8253795, GO:0030867=GO_REF:0000019, GO:0006468=GO_REF:0000019, GO:0007601=GO_REF:0000037, GO:0001750=PMID:11767049, GO:0016056=GO_REF:0000019, GO:0060342=PMID:19934218} P08100 Rhodopsin protein 20100607 {GO:0005515=IPI, GO:0005794=IDA, GO:0005886=IDA, GO:0007603=TAS, GO:0060041=IEA, GO:0004930=IEA, GO:0042622=IDA, GO:0016918=IEA, GO:0001523=TAS, GO:0046872=IEA, GO:0009585=IEA, GO:0001917=IDA, GO:0018298=IEA, GO:0097381=TAS, GO:0009881=IEA, GO:0007186=TAS, GO:0005887=TAS, GO:0030867=IEA, GO:0006468=IEA, GO:0007601=IEA, GO:0001750=IDA, GO:0016056=IEA, GO:0060342=IDA} G-protein coupled receptor signaling pathway, phototransduction, visible light, protein phosphorylation, protein-chromophore linkage, red, far-red light phototransduction, retina development in camera-type eye, retinoid metabolic process, rhodopsin mediated signaling pathway, visual perception Golgi apparatus, integral to plasma membrane, photoreceptor disc membrane, photoreceptor inner segment, photoreceptor inner segment membrane, photoreceptor outer segment, photoreceptor outer segment membrane, plasma membrane, rough endoplasmic reticulum membrane G-protein coupled receptor activity, metal ion binding, photoreceptor activity, protein binding, retinal binding Human RHOA BHF-UCL UniProtKB {GO:0005515=PMID:10051605, GO:0033688=GO_REF:0000024, GO:0030054=Reactome:REACT_121319, GO:0043931=GO_REF:0000024, GO:0030307=GO_REF:0000019, GO:0036089=PMID:16103226, GO:0005622=GO_REF:0000002, GO:0043524=GO_REF:0000019, GO:0043525=GO_REF:0000019, GO:0030838=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0051924=GO_REF:0000019, GO:0007179=Reactome:REACT_120726, GO:0043123=PMID:12761501, GO:0005856=GO_REF:0000039, GO:0005938=PMID:16103226, GO:0043124=GO_REF:0000019, GO:0030334=PMID:19934221, GO:0030335=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0030496=GO_REF:0000039, GO:0051384=GO_REF:0000019, GO:0030027=GO_REF:0000019, GO:0045785=GO_REF:0000019, GO:0043280=GO_REF:0000019, GO:0007519=GO_REF:0000019, GO:0051496=PMID:15467718, GO:0050773=GO_REF:0000019, GO:0050771=Reactome:REACT_13815, GO:0017022=PMID:15644318, GO:0050772=Reactome:REACT_13779, GO:0050770=Reactome:REACT_13620, GO:0042346=PMID:12761501, GO:0030424=GO_REF:0000019, GO:0071803=GO_REF:0000019, GO:0030036=PMID:10436159, GO:0005886=Reactome:REACT_19389, GO:0007264=Reactome:REACT_11044, GO:0045471=GO_REF:0000019, GO:0043149=GO_REF:0000019, GO:0033144=GO_REF:0000019, GO:0003924=PMID:10436159, GO:0005634=GO_REF:0000019, GO:0007266=PMID:10436159, GO:0032154=GO_REF:0000039, GO:0005829=Reactome:REACT_23936, GO:0005739=GO_REF:0000019, GO:0043297=PMID:20974804, GO:0043296=PMID:20974804, GO:0045907=GO_REF:0000019, GO:0090307=PMID:19635168, GO:0043200=GO_REF:0000019, GO:0031098=GO_REF:0000019, GO:0051056=Reactome:REACT_11051, GO:0001666=GO_REF:0000019, GO:0048011=Reactome:REACT_13776, GO:0006357=GO_REF:0000019, GO:0048015=Reactome:REACT_12464, GO:0042493=GO_REF:0000019, GO:0045727=GO_REF:0000019, GO:0061383=GO_REF:0000024, GO:0032587=GO_REF:0000019, GO:0005525=GO_REF:0000037, GO:0009612=GO_REF:0000019, GO:0009749=GO_REF:0000019, GO:0045665=GO_REF:0000019, GO:0016020=GO_REF:0000038, GO:0007160=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0045666=PMID:17488780, GO:0048812=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0030521=GO_REF:0000019} P61586 Transforming protein RhoA protein 20110613 {GO:0005515=IPI, GO:0033688=ISS, GO:0030054=TAS, GO:0043931=ISS, GO:0030307=IEA, GO:0036089=IDA, GO:0005622=IEA, GO:0043524=IEA, GO:0043525=IEA, GO:0030838=IEA, GO:0007411=TAS, GO:0051924=IEA, GO:0007179=TAS, GO:0043123=IEP, GO:0005856=IEA, GO:0005938=IDA, GO:0043124=IEA, GO:0030334=IMP, GO:0030335=IEA, GO:0019904=IEA, GO:0030168=TAS, GO:0030496=IEA, GO:0051384=IEA, GO:0030027=IEA, GO:0045785=IEA, GO:0043280=IEA, GO:0007519=IEA, GO:0051496=IDA, GO:0050773=IEA, GO:0050771=TAS, GO:0017022=IPI, GO:0050772=TAS, GO:0050770=TAS, GO:0042346=NAS, GO:0030424=IEA, GO:0071803=IEA, GO:0030036=TAS, GO:0005886=TAS, GO:0007264=TAS, GO:0045471=IEA, GO:0043149=IEA, GO:0033144=IEA, GO:0003924=TAS, GO:0005634=IEA, GO:0007266=TAS, GO:0032154=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0043297=IMP, GO:0043296=IDA, GO:0045907=IEA, GO:0090307=IMP, GO:0043200=IEA, GO:0031098=IEA, GO:0051056=TAS, GO:0001666=IEA, GO:0048011=TAS, GO:0006357=IEA, GO:0048015=TAS, GO:0042493=IEA, GO:0045727=IEA, GO:0061383=ISS, GO:0032587=IEA, GO:0005525=IEA, GO:0009612=IEA, GO:0009749=IEA, GO:0045665=IEA, GO:0016020=IEA, GO:0007160=IEA, GO:0007596=TAS, GO:0045666=IMP, GO:0048812=IEA, GO:0019048=IEA, GO:0030521=IEA} Rho protein signal transduction, actin cytoskeleton organization, androgen receptor signaling pathway, apical junction assembly, axon guidance, blood coagulation, cell-matrix adhesion, cleavage furrow formation, negative regulation of I-kappaB kinase/NF-kappaB cascade, negative regulation of axonogenesis, negative regulation of intracellular steroid hormone receptor signaling pathway, negative regulation of neuron apoptotic process, negative regulation of neuron differentiation, neuron projection morphogenesis, neurotrophin TRK receptor signaling pathway, ossification involved in bone maturation, phosphatidylinositol-mediated signaling, platelet activation, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB import into nucleus, positive regulation of actin filament polymerization, positive regulation of axonogenesis, positive regulation of cell adhesion, positive regulation of cell growth, positive regulation of cell migration, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of neuron apoptotic process, positive regulation of neuron differentiation, positive regulation of podosome assembly, positive regulation of stress fiber assembly, positive regulation of translation, positive regulation of vasoconstriction, regulation of axonogenesis, regulation of calcium ion transport, regulation of cell migration, regulation of dendrite development, regulation of osteoblast proliferation, regulation of small GTPase mediated signal transduction, regulation of transcription from RNA polymerase II promoter, response to amino acid stimulus, response to drug, response to ethanol, response to glucocorticoid stimulus, response to glucose stimulus, response to hypoxia, response to mechanical stimulus, skeletal muscle tissue development, small GTPase mediated signal transduction, spindle assembly involved in mitosis, stress fiber assembly, stress-activated protein kinase signaling cascade, trabecula morphogenesis, transforming growth factor beta receptor signaling pathway, virus-host interaction apical junction complex, axon, cell cortex, cell junction, cleavage furrow, cytoskeleton, cytosol, intracellular, lamellipodium, membrane, midbody, mitochondrion, nucleus, plasma membrane, ruffle membrane GTP binding, GTPase activity, myosin binding, protein binding, protein domain specific binding Human RHOB GOC UniProtKB {GO:0070301=PMID:21373644, GO:0005886=Reactome:REACT_19389, GO:0007264=Reactome:REACT_11044, GO:0006927=GO_REF:0000024, GO:0003924=PMID:3888408, GO:0005634=GO_REF:0000024, GO:0007266=PMID:3888408, GO:0015031=GO_REF:0000037, GO:0032154=PMID:16236794, GO:0005829=Reactome:REACT_23806, GO:0007411=Reactome:REACT_18266, GO:0007155=GO_REF:0000024, GO:0051056=Reactome:REACT_11051, GO:0043065=PMID:21373644, GO:0008333=PMID:10508588, GO:0006915=PMID:19637314, GO:0030168=Reactome:REACT_798, GO:0001525=GO_REF:0000037, GO:0045786=GO_REF:0000024, GO:0005525=PMID:1400319, GO:0045766=GO_REF:0000024, GO:0071479=PMID:21373644, GO:0006184=PMID:3888408, GO:0007596=Reactome:REACT_604, GO:0031902=GO_REF:0000039, GO:0019003=GO_REF:0000019, GO:0010008=PMID:19637314} P62745 Rho-related GTP-binding protein RhoB protein 20130413 {GO:0070301=IDA, GO:0005886=TAS, GO:0007264=TAS, GO:0006927=ISS, GO:0003924=TAS, GO:0005634=ISS, GO:0007266=TAS, GO:0015031=IEA, GO:0032154=IDA, GO:0005829=TAS, GO:0007411=TAS, GO:0007155=ISS, GO:0051056=TAS, GO:0043065=IMP, GO:0008333=IDA, GO:0006915=TAS, GO:0030168=TAS, GO:0001525=IEA, GO:0045786=ISS, GO:0005525=TAS, GO:0045766=ISS, GO:0071479=IDA, GO:0006184=TAS, GO:0007596=TAS, GO:0031902=IEA, GO:0019003=IEA, GO:0010008=IDA} GTP catabolic process, Rho protein signal transduction, angiogenesis, apoptotic process, axon guidance, blood coagulation, cell adhesion, cellular response to hydrogen peroxide, cellular response to ionizing radiation, endosome to lysosome transport, negative regulation of cell cycle, platelet activation, positive regulation of angiogenesis, positive regulation of apoptotic process, protein transport, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction, transformed cell apoptotic process cleavage furrow, cytosol, endosome membrane, late endosome membrane, nucleus, plasma membrane GDP binding, GTP binding, GTPase activity Human RHOBTB1 Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0005886=Reactome:REACT_10126, GO:0007264=Reactome:REACT_11044, GO:0005525=GO_REF:0000037, GO:0005829=Reactome:REACT_10055} O94844 Rho-related BTB domain-containing protein 1 protein 20130301 {GO:0051056=TAS, GO:0005886=TAS, GO:0007264=TAS, GO:0005525=IEA, GO:0005829=TAS} regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol, plasma membrane GTP binding Human RHOBTB2 Reactome UniProtKB {GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0005886=Reactome:REACT_10126, GO:0016020=GO_REF:0000038, GO:0007264=Reactome:REACT_11044, GO:0005525=GO_REF:0000037, GO:0005829=Reactome:REACT_10055} Q9BYZ6 Rho-related BTB domain-containing protein 2 protein 20130301 {GO:0005622=IEA, GO:0051056=TAS, GO:0005886=TAS, GO:0016020=IEA, GO:0007264=TAS, GO:0005525=IEA, GO:0005829=TAS} regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol, intracellular, membrane, plasma membrane GTP binding Human RHOBTB3 GOC UniProtKB {GO:0005515=PMID:19490898, GO:0017137=PMID:19490898, GO:0005794=GO_REF:0000039, GO:0006200=PMID:19490898, GO:0007264=GO_REF:0000002, GO:0042147=PMID:19490898, GO:0005525=GO_REF:0000002, GO:0016887=PMID:19490898, GO:0005524=PMID:19490898} O94955 Rho-related BTB domain-containing protein 3 protein 20130413 {GO:0005515=IPI, GO:0017137=IPI, GO:0005794=IEA, GO:0006200=IDA, GO:0007264=IEA, GO:0042147=IMP, GO:0005525=IEA, GO:0016887=IDA, GO:0005524=IDA} ATP catabolic process, retrograde transport, endosome to Golgi, small GTPase mediated signal transduction Golgi apparatus ATP binding, ATPase activity, GTP binding, Rab GTPase binding, protein binding Human RHOC ENSEMBL UniProtKB {GO:0005515=PMID:20974804, GO:0051056=Reactome:REACT_11051, GO:0005886=GO_REF:0000019, GO:0007264=GO_REF:0000002, GO:0005634=GO_REF:0000019, GO:0005525=GO_REF:0000002, GO:0032154=PMID:16236794, GO:0005829=GO_REF:0000019, GO:0005622=GO_REF:0000002, GO:0043297=GO_REF:0000019, GO:0016020=GO_REF:0000038, GO:0007411=Reactome:REACT_18266, GO:0004871=PMID:12761501, GO:0043123=PMID:12761501} Q5JR08 Rho-related GTP-binding protein RhoC protein 20130413 {GO:0005515=IPI, GO:0051056=TAS, GO:0005886=IEA, GO:0007264=IEA, GO:0005634=IEA, GO:0005525=IEA, GO:0032154=IDA, GO:0005829=IEA, GO:0005622=IEA, GO:0043297=IEA, GO:0016020=IEA, GO:0007411=TAS, GO:0004871=IMP, GO:0043123=IMP} apical junction assembly, axon guidance, positive regulation of I-kappaB kinase/NF-kappaB cascade, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cleavage furrow, cytosol, intracellular, membrane, nucleus, plasma membrane GTP binding, protein binding, signal transducer activity Human Ensembl:ENSMUSP00000002303 RHOD GOC UniProtKB {GO:0006184=PMID:9116026, GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0005886=Reactome:REACT_10126, GO:0016020=GO_REF:0000038, GO:0007264=Reactome:REACT_11044, GO:0003924=PMID:9116026, GO:0007266=PMID:9116026, GO:0005525=GO_REF:0000019, GO:0005829=Reactome:REACT_10055} O00212 Rho-related GTP-binding protein RhoD protein 20130413 {GO:0006184=TAS, GO:0005622=IEA, GO:0051056=TAS, GO:0005886=TAS, GO:0016020=IEA, GO:0007264=TAS, GO:0003924=TAS, GO:0007266=TAS, GO:0005525=IEA, GO:0005829=TAS} GTP catabolic process, Rho protein signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol, intracellular, membrane, plasma membrane GTP binding, GTPase activity Human RHOF GOC UniProtKB {GO:0006184=PMID:11084341, GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0005886=Reactome:REACT_10126, GO:0016020=GO_REF:0000038, GO:0007264=Reactome:REACT_11044, GO:0003924=PMID:11084341, GO:0007015=PMID:11084341, GO:0005856=PMID:11084341, GO:0005525=GO_REF:0000037, GO:0005829=Reactome:REACT_10055} Q9HBH0 Rho-related GTP-binding protein RhoF protein 20130413 {GO:0006184=NAS, GO:0005622=IEA, GO:0051056=TAS, GO:0005886=TAS, GO:0016020=IEA, GO:0007264=TAS, GO:0003924=NAS, GO:0007015=IDA, GO:0005856=NAS, GO:0005525=IEA, GO:0005829=TAS} GTP catabolic process, actin filament organization, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytoskeleton, cytosol, intracellular, membrane, plasma membrane GTP binding, GTPase activity Human RHOG GOC UniProtKB {GO:0005515=PMID:12879077, GO:0051056=Reactome:REACT_11051, GO:0008284=PMID:1620121, GO:0030036=PMID:12545154, GO:0005886=Reactome:REACT_10126, GO:0007264=Reactome:REACT_11044, GO:0003924=PMID:12376551, GO:0030168=Reactome:REACT_798, GO:0007266=PMID:12376551, GO:0005525=GO_REF:0000037, GO:0032863=PMID:20679435, GO:0005829=Reactome:REACT_24016, GO:0006184=PMID:1620121, GO:0016601=PMID:12376551, GO:0007411=Reactome:REACT_18266, GO:0060326=PMID:20679435, GO:0007596=Reactome:REACT_604, GO:0045893=PMID:12545154, GO:0090004=PMID:20679435} P84095 Rho-related GTP-binding protein RhoG protein 20130413 {GO:0005515=IPI, GO:0051056=TAS, GO:0008284=TAS, GO:0030036=IDA, GO:0005886=TAS, GO:0007264=TAS, GO:0003924=IDA, GO:0030168=TAS, GO:0007266=IDA, GO:0005525=IEA, GO:0032863=IMP, GO:0005829=TAS, GO:0006184=TAS, GO:0016601=IDA, GO:0007411=TAS, GO:0060326=IMP, GO:0007596=TAS, GO:0045893=IDA, GO:0090004=IMP} GTP catabolic process, Rac protein signal transduction, Rho protein signal transduction, actin cytoskeleton organization, activation of Rac GTPase activity, axon guidance, blood coagulation, cell chemotaxis, platelet activation, positive regulation of cell proliferation, positive regulation of establishment of protein localization to plasma membrane, positive regulation of transcription, DNA-dependent, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol, plasma membrane GTP binding, GTPase activity, protein binding Human RHOH GOC UniProtKB {GO:0001772=GO_REF:0000019, GO:0005515=PMID:11809807, GO:0051056=Reactome:REACT_11051, GO:0045576=GO_REF:0000019, GO:0006355=PMID:11809807, GO:0005886=Reactome:REACT_10126, GO:0007264=Reactome:REACT_11044, GO:0019210=PMID:11809807, GO:0005525=PMID:11809807, GO:0005829=Reactome:REACT_10055, GO:0042326=PMID:11809807, GO:0005739=GO_REF:0000052, GO:0005737=PMID:11809807, GO:0030217=PMID:11809807, GO:0017048=PMID:11809807, GO:0005095=PMID:11809807, GO:0043124=PMID:11809807} Q15669 Rho-related GTP-binding protein RhoH protein 20130413 {GO:0001772=IEA, GO:0005515=IPI, GO:0051056=TAS, GO:0045576=IEA, GO:0006355=NAS, GO:0005886=TAS, GO:0007264=TAS, GO:0019210=IDA, GO:0005525=IDA, GO:0005829=TAS, GO:0042326=IDA, GO:0005739=IDA, GO:0005737=IDA, GO:0030217=NAS, GO:0017048=NAS, GO:0005095=NAS, GO:0043124=IDA} T cell differentiation, mast cell activation, negative regulation of I-kappaB kinase/NF-kappaB cascade, negative regulation of phosphorylation, regulation of small GTPase mediated signal transduction, regulation of transcription, DNA-dependent, small GTPase mediated signal transduction cytoplasm, cytosol, immunological synapse, mitochondrion, plasma membrane GTP binding, GTPase inhibitor activity, Rho GTPase binding, kinase inhibitor activity, protein binding Human RHOJ GOC UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0030036=PMID:10967094, GO:0005886=Reactome:REACT_10126, GO:0007264=Reactome:REACT_11044, GO:0008360=GO_REF:0000019, GO:0003924=PMID:10967094, GO:0007266=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0005525=GO_REF:0000037, GO:0005829=Reactome:REACT_10055, GO:0005622=GO_REF:0000002, GO:0006184=PMID:10967094, GO:0016020=GO_REF:0000038} Q9H4E5 Rho-related GTP-binding protein RhoJ protein 20130413 {GO:0051056=TAS, GO:0030036=IMP, GO:0005886=TAS, GO:0007264=TAS, GO:0008360=IEA, GO:0003924=NAS, GO:0007266=IEA, GO:0005575=ND, GO:0005525=IEA, GO:0005829=TAS, GO:0005622=IEA, GO:0006184=NAS, GO:0016020=IEA} GTP catabolic process, Rho protein signal transduction, actin cytoskeleton organization, regulation of cell shape, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cellular_component, cytosol, intracellular, membrane, plasma membrane GTP binding, GTPase activity Human RHOQ BHF-UCL UniProtKB {GO:0008286=PMID:11309621, GO:0032427=PMID:10445846, GO:0051056=Reactome:REACT_11051, GO:0032869=PMID:11309621, GO:0005886=PMID:10445846, GO:0007264=Reactome:REACT_11044, GO:0005884=PMID:10445846, GO:0008360=GO_REF:0000019, GO:0003924=PMID:10445846, GO:0051491=PMID:10445846, GO:0005525=GO_REF:0000037, GO:0005829=Reactome:REACT_10055, GO:0006184=PMID:10445846, GO:0030866=PMID:11821390, GO:0046326=PMID:11309621, GO:0045944=PMID:10445846, GO:0032956=PMID:10445846, GO:0090005=PMID:11309621, GO:0045121=GO_REF:0000019, GO:0005522=PMID:10445846} P17081 Rho-related GTP-binding protein RhoQ protein 20090302 {GO:0008286=IMP, GO:0032427=IPI, GO:0051056=TAS, GO:0032869=IMP, GO:0005886=IDA, GO:0007264=TAS, GO:0005884=IDA, GO:0008360=IEA, GO:0003924=IDA, GO:0051491=IDA, GO:0005525=IEA, GO:0005829=TAS, GO:0006184=IDA, GO:0030866=IMP, GO:0046326=IMP, GO:0045944=IDA, GO:0032956=IC, GO:0090005=IMP, GO:0045121=IEA, GO:0005522=IPI} GTP catabolic process, cellular response to insulin stimulus, cortical actin cytoskeleton organization, insulin receptor signaling pathway, negative regulation of establishment of protein localization to plasma membrane, positive regulation of filopodium assembly, positive regulation of glucose import, positive regulation of transcription from RNA polymerase II promoter, regulation of actin cytoskeleton organization, regulation of cell shape, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction actin filament, cytosol, membrane raft, plasma membrane GBD domain binding, GTP binding, GTPase activity, profilin binding Human RHOT1 IntAct UniProtKB {GO:0005515=PMID:22078885, GO:0051056=Reactome:REACT_11051, GO:0019725=PMID:12482879, GO:0005886=Reactome:REACT_10126, GO:0007264=Reactome:REACT_11044, GO:0005509=GO_REF:0000002, GO:0003924=GO_REF:0000002, GO:0006915=PMID:12482879, GO:0005741=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0005829=Reactome:REACT_10055, GO:0005622=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0047497=PMID:16630562, GO:0031307=PMID:19528298} Q8IXI2 Mitochondrial Rho GTPase 1 protein 20130415 {GO:0005515=IPI, GO:0051056=TAS, GO:0019725=IMP, GO:0005886=TAS, GO:0007264=TAS, GO:0005509=IEA, GO:0003924=IEA, GO:0006915=IMP, GO:0005741=IEA, GO:0005525=IEA, GO:0005829=TAS, GO:0005622=IEA, GO:0003674=ND, GO:0047497=IMP, GO:0031307=IDA} apoptotic process, cellular homeostasis, mitochondrion transport along microtubule, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol, integral to mitochondrial outer membrane, intracellular, mitochondrial outer membrane, plasma membrane GTP binding, GTPase activity, calcium ion binding, molecular_function, protein binding Human UniProtKB:Q9BXM7 RHOT2 Reactome UniProtKB {GO:0005515=PMID:19528298, GO:0051056=Reactome:REACT_11051, GO:0019725=PMID:12482879, GO:0005886=Reactome:REACT_10126, GO:0007264=Reactome:REACT_11044, GO:0005509=GO_REF:0000002, GO:0003924=GO_REF:0000002, GO:0006915=PMID:12482879, GO:0005525=GO_REF:0000037, GO:0005829=Reactome:REACT_10055, GO:0005622=GO_REF:0000002, GO:0047497=PMID:16630562, GO:0031307=PMID:19528298} Q8IXI1 Mitochondrial Rho GTPase 2 protein 20130301 {GO:0005515=IPI, GO:0051056=TAS, GO:0019725=IMP, GO:0005886=TAS, GO:0007264=TAS, GO:0005509=IEA, GO:0003924=IEA, GO:0006915=IMP, GO:0005525=IEA, GO:0005829=TAS, GO:0005622=IEA, GO:0047497=IMP, GO:0031307=IDA} apoptotic process, cellular homeostasis, mitochondrion transport along microtubule, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol, integral to mitochondrial outer membrane, intracellular, plasma membrane GTP binding, GTPase activity, calcium ion binding, protein binding Human RHOU IntAct UniProtKB {GO:0005515=PMID:18086875, GO:0051056=Reactome:REACT_11051, GO:0030036=GO_REF:0000019, GO:0005886=Reactome:REACT_10126, GO:0007264=Reactome:REACT_11044, GO:0008360=PMID:21834987, GO:0003924=GO_REF:0000019, GO:0002102=GO_REF:0000039, GO:0042995=GO_REF:0000037, GO:0005525=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_10055, GO:0000082=GO_REF:0000019, GO:0016601=GO_REF:0000019, GO:0000139=GO_REF:0000039, GO:0007010=PMID:21834987, GO:0005925=GO_REF:0000039} Q7L0Q8 Rho-related GTP-binding protein RhoU protein 20130415 {GO:0005515=IPI, GO:0051056=TAS, GO:0030036=IEA, GO:0005886=TAS, GO:0007264=TAS, GO:0008360=IMP, GO:0003924=IEA, GO:0002102=IEA, GO:0042995=IEA, GO:0005525=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0000082=IEA, GO:0016601=IEA, GO:0000139=IEA, GO:0007010=IMP, GO:0005925=IEA} G1/S transition of mitotic cell cycle, Rac protein signal transduction, actin cytoskeleton organization, cytoskeleton organization, regulation of cell shape, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction Golgi membrane, cell projection, cytosol, focal adhesion, plasma membrane, podosome GTP binding, GTPase activity, metal ion binding, protein binding Human UniProtKB:Q14289 RHOV Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0005886=Reactome:REACT_10126, GO:0007264=Reactome:REACT_11044, GO:0005525=GO_REF:0000037, GO:0010008=GO_REF:0000039, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_10055} Q96L33 Rho-related GTP-binding protein RhoV protein 20130301 {GO:0051056=TAS, GO:0005886=TAS, GO:0007264=TAS, GO:0005525=IEA, GO:0010008=IEA, GO:0046872=IEA, GO:0005829=TAS} regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol, endosome membrane, plasma membrane GTP binding, metal ion binding Human RHOXF1 UniProtKB UniProtKB {GO:0019953=PMID:11980563, GO:0006355=PMID:11980563, GO:0000976=GO_REF:0000002, GO:0003700=PMID:12490318, GO:0030518=PMID:11980563, GO:0007276=PMID:11980563, GO:0007275=PMID:11980563, GO:0005634=PMID:11980563, GO:0003677=PMID:11980563, GO:0006351=GO_REF:0000037} Q8NHV9 Rhox homeobox family member 1 protein 20031201 {GO:0019953=IEP, GO:0006355=NAS, GO:0000976=IEA, GO:0003700=NAS, GO:0030518=NAS, GO:0007276=NAS, GO:0007275=NAS, GO:0005634=IDA, GO:0003677=NAS, GO:0006351=IEA} gamete generation, intracellular steroid hormone receptor signaling pathway, multicellular organismal development, regulation of transcription, DNA-dependent, sexual reproduction, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding Human RHOXF2 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0005634=GO_REF:0000039} Q9BQY4 Rhox homeobox family member 2 protein 20130415 {GO:0005515=IPI, GO:0043565=IEA, GO:0003700=IEA, GO:0005634=IEA} nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:Q15038 RHPN1 ENSEMBL UniProtKB {GO:0007165=GO_REF:0000002, GO:0005083=GO_REF:0000019} Q8TCX5 Rhophilin-1 protein 20130413 {GO:0007165=IEA, GO:0005083=IEA} signal transduction small GTPase regulator activity Human Ensembl:ENSMUSP00000113042 RHPN2 UniProtKB UniProtKB {GO:0007165=GO_REF:0000002, GO:0048471=GO_REF:0000039} Q8IUC4 Rhophilin-2 protein 20130413 {GO:0007165=IEA, GO:0048471=IEA} signal transduction perinuclear region of cytoplasm Human UniProtKB-SubCell:SL-0198 RIBC1 null null {} null null null null {} null null null RIBC2 null null {} null null null null {} null null null RIC3 UniProtKB UniProtKB {GO:0000139=GO_REF:0000039, GO:0044183=GO_REF:0000019, GO:0005783=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000019, GO:0043623=GO_REF:0000019} Q7Z5B4 Protein RIC-3 protein 20130413 {GO:0000139=IEA, GO:0044183=IEA, GO:0005783=IEA, GO:0005789=IEA, GO:0016021=IEA, GO:0043623=IEA} cellular protein complex assembly Golgi membrane, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane protein binding involved in protein folding Human UniProtKB-SubCell:SL-0097 RIC8A UniProtKB UniProtKB {GO:0005085=GO_REF:0000037, GO:0005737=GO_REF:0000024, GO:0042074=GO_REF:0000019, GO:0005886=GO_REF:0000024, GO:0016020=GO_REF:0000019, GO:0008542=GO_REF:0000019, GO:0071711=GO_REF:0000019, GO:0070586=GO_REF:0000019, GO:0007193=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0001944=GO_REF:0000019} Q9NPQ8 Synembryn-A protein 20110325 {GO:0005085=IEA, GO:0005737=ISS, GO:0042074=IEA, GO:0005886=ISS, GO:0016020=IEA, GO:0008542=IEA, GO:0071711=IEA, GO:0070586=IEA, GO:0007193=IEA, GO:0001701=IEA, GO:0001944=IEA} adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, basement membrane organization, cell migration involved in gastrulation, cell-cell adhesion involved in gastrulation, in utero embryonic development, vasculature development, visual learning cytoplasm, membrane, plasma membrane guanyl-nucleotide exchange factor activity Human UniProtKB:Q80ZG1 RIC8B HPA UniProtKB {GO:0005085=GO_REF:0000037, GO:0001965=PMID:12652642, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0008277=PMID:12652642, GO:0005886=PMID:12652642, GO:0005938=GO_REF:0000039, GO:0005829=PMID:12652642} Q9NVN3 Synembryn-B protein 20111111 {GO:0005085=IEA, GO:0001965=IDA, GO:0005813=IDA, GO:0005737=IDA, GO:0008277=IDA, GO:0005886=IDA, GO:0005938=IEA, GO:0005829=IDA} regulation of G-protein coupled receptor protein signaling pathway cell cortex, centrosome, cytoplasm, cytosol, plasma membrane G-protein alpha-subunit binding, guanyl-nucleotide exchange factor activity Human RICTOR IntAct UniProtKB {GO:0005515=PMID:21339740, GO:0048011=Reactome:REACT_11061, GO:0032008=PMID:15467718, GO:0031532=PMID:15268862, GO:0048015=Reactome:REACT_12464, GO:0031295=Reactome:REACT_19344, GO:0050731=GO_REF:0000019, GO:0009790=GO_REF:0000024, GO:0051896=PMID:15718470, GO:0005829=Reactome:REACT_147858, GO:0032314=GO_REF:0000019, GO:0030838=GO_REF:0000019, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0032956=PMID:15467718, GO:0043022=GO_REF:0000019, GO:0031932=PMID:15467718} Q6R327 Rapamycin-insensitive companion of mTOR protein 20130415 {GO:0005515=IPI, GO:0048011=TAS, GO:0032008=IMP, GO:0031532=IMP, GO:0048015=TAS, GO:0031295=TAS, GO:0050731=IEA, GO:0009790=ISS, GO:0051896=IDA, GO:0005829=TAS, GO:0032314=IEA, GO:0030838=IEA, GO:0007173=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0032956=IMP, GO:0043022=IEA, GO:0031932=IDA} T cell costimulation, actin cytoskeleton reorganization, embryo development, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of TOR signaling cascade, positive regulation of actin filament polymerization, positive regulation of peptidyl-tyrosine phosphorylation, regulation of Rac GTPase activity, regulation of actin cytoskeleton organization, regulation of protein kinase B signaling cascade TORC2 complex, cytosol protein binding, ribosome binding Human UniProtKB:Q8TCU6 RIF1 UniProtKB UniProtKB {GO:0007049=GO_REF:0000037, GO:0005737=GO_REF:0000037, GO:0000781=GO_REF:0000039, GO:0001939=GO_REF:0000019, GO:0019827=GO_REF:0000019, GO:0005819=GO_REF:0000039, GO:0001940=GO_REF:0000019, GO:0006974=GO_REF:0000037} Q5UIP0 Telomere-associated protein RIF1 protein 20130413 {GO:0007049=IEA, GO:0005737=IEA, GO:0000781=IEA, GO:0001939=IEA, GO:0019827=IEA, GO:0005819=IEA, GO:0001940=IEA, GO:0006974=IEA} cell cycle, response to DNA damage stimulus, stem cell maintenance chromosome, telomeric region, cytoplasm, female pronucleus, male pronucleus, spindle Human UniProtKB-SubCell:SL-0251 RIIAD1 InterPro UniProtKB {GO:0007165=GO_REF:0000002, GO:0008603=GO_REF:0000002} C9JPK7 RIIa domain-containing protein 1 protein 20130413 {GO:0007165=IEA, GO:0008603=IEA} signal transduction cAMP-dependent protein kinase regulator activity Human InterPro:IPR003117 RILP BHF-UCL UniProtKB {GO:0005515=PMID:22261744, GO:0005739=GO_REF:0000019, GO:0019886=Reactome:REACT_121399, GO:0017137=PMID:18272684, GO:0005770=PMID:18272684, GO:0008333=PMID:18272684, GO:0031902=GO_REF:0000039, GO:0030670=GO_REF:0000039, GO:0005765=Reactome:REACT_120995, GO:0015031=PMID:11179213, GO:0005764=PMID:18272684} Q96NA2 Rab-interacting lysosomal protein protein 20101221 {GO:0005515=IPI, GO:0005739=IEA, GO:0019886=TAS, GO:0017137=IPI, GO:0005770=IDA, GO:0008333=IMP, GO:0031902=IEA, GO:0030670=IEA, GO:0005765=TAS, GO:0015031=NAS, GO:0005764=IDA} antigen processing and presentation of exogenous peptide antigen via MHC class II, endosome to lysosome transport, protein transport late endosome, late endosome membrane, lysosomal membrane, lysosome, mitochondrion, phagocytic vesicle membrane Rab GTPase binding, protein binding Human RILPL1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:1901214=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0005829=GO_REF:0000024} Q5EBL4 RILP-like protein 1 protein 20111111 {GO:0005737=IDA, GO:0005886=IDA, GO:0005730=IDA, GO:1901214=ISS, GO:0005634=IDA, GO:0005829=ISS} regulation of neuron death cytoplasm, cytosol, nucleolus, nucleus, plasma membrane Human RILPL2 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0042802=PMID:16189514, GO:0005829=GO_REF:0000039} Q969X0 RILP-like protein 2 protein 20101115 {GO:0005737=IDA, GO:0005886=IDA, GO:0042802=IPI, GO:0005829=IEA} cytoplasm, cytosol, plasma membrane identical protein binding Human RIMBP2 UniProtKB UniProtKB {GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0010923=PMID:19389623, GO:0045202=GO_REF:0000039} O15034 RIMS-binding protein 2 protein 20111103 {GO:0030054=IEA, GO:0005886=IEA, GO:0010923=IDA, GO:0045202=IEA} negative regulation of phosphatase activity cell junction, plasma membrane, synapse Human RIMBP3C null null {} null null null null {} null null null RIMKLA UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0016881=GO_REF:0000003, GO:0072590=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0006464=GO_REF:0000002} Q8IXN7 N-acetylaspartyl-glutamate synthetase A protein 20120924 {GO:0005737=IEA, GO:0016881=IEA, GO:0072590=ISS, GO:0005524=IEA, GO:0046872=IEA, GO:0006464=IEA} cellular protein modification process cytoplasm ATP binding, N-acetyl-L-aspartate-L-glutamate ligase activity, acid-amino acid ligase activity, metal ion binding Human UniProtKB:Q6PFX8 RIMKLB UniProtKB UniProtKB {GO:0005737=GO_REF:0000024, GO:0016881=GO_REF:0000003, GO:0072591=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0072590=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0006464=GO_REF:0000002} Q9ULI2 Beta-citryl-glutamate synthase B protein 20120924 {GO:0005737=ISS, GO:0016881=IEA, GO:0072591=ISS, GO:0005524=IEA, GO:0072590=ISS, GO:0046872=IEA, GO:0006464=IEA} cellular protein modification process cytoplasm ATP binding, N-acetyl-L-aspartate-L-glutamate ligase activity, acid-amino acid ligase activity, citrate-L-glutamate ligase activity, metal ion binding Human UniProtKB:Q80WS1 RIMS1 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0017137=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_23973, GO:0048791=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0014047=Reactome:REACT_12591, GO:0006886=GO_REF:0000002, GO:0016079=PMID:11438518, GO:0007269=Reactome:REACT_13723, GO:0046903=PMID:11438518, GO:0046872=GO_REF:0000037, GO:0044325=GO_REF:0000019, GO:0045055=PMID:11438518, GO:0042734=GO_REF:0000024, GO:0005083=PMID:11438518, GO:0006461=PMID:11438518, GO:0006944=PMID:11438518, GO:0017156=PMID:11438518, GO:0042391=GO_REF:0000019, GO:0048169=GO_REF:0000019, GO:0007601=GO_REF:0000037, GO:0050896=GO_REF:0000037} Q86UR5 Regulating synaptic membrane exocytosis protein 1 protein 20130415 {GO:0005515=IPI, GO:0017137=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0048791=IEA, GO:0007268=TAS, GO:0014047=TAS, GO:0006886=IEA, GO:0016079=TAS, GO:0007269=TAS, GO:0046903=NAS, GO:0046872=IEA, GO:0044325=IEA, GO:0045055=NAS, GO:0042734=ISS, GO:0005083=TAS, GO:0006461=IDA, GO:0006944=NAS, GO:0017156=TAS, GO:0042391=IEA, GO:0048169=IEA, GO:0007601=IEA, GO:0050896=IEA} calcium ion-dependent exocytosis, calcium ion-dependent exocytosis of neurotransmitter, cellular membrane fusion, glutamate secretion, intracellular protein transport, neurotransmitter secretion, protein complex assembly, regulated secretory pathway, regulation of long-term neuronal synaptic plasticity, regulation of membrane potential, response to stimulus, secretion, synaptic transmission, synaptic vesicle exocytosis, visual perception cell junction, plasma membrane, presynaptic membrane Rab GTPase binding, ion channel binding, metal ion binding, protein binding, small GTPase regulator activity Human UniProtKB:P00519 RIMS2 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0017137=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000039, GO:0048791=GO_REF:0000019, GO:0006886=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0044325=GO_REF:0000019, GO:0042734=GO_REF:0000039, GO:0017156=GO_REF:0000019, GO:0019933=GO_REF:0000019, GO:0042391=GO_REF:0000019, GO:0030073=GO_REF:0000019} Q9UQ26 Regulating synaptic membrane exocytosis protein 2 protein 20130415 {GO:0005515=IPI, GO:0017137=IEA, GO:0030054=IEA, GO:0005886=IEA, GO:0048791=IEA, GO:0006886=IEA, GO:0046872=IEA, GO:0044325=IEA, GO:0042734=IEA, GO:0017156=IEA, GO:0019933=IEA, GO:0042391=IEA, GO:0030073=IEA} cAMP-mediated signaling, calcium ion-dependent exocytosis, calcium ion-dependent exocytosis of neurotransmitter, insulin secretion, intracellular protein transport, regulation of membrane potential cell junction, plasma membrane, presynaptic membrane Rab GTPase binding, ion channel binding, metal ion binding, protein binding Human UniProtKB:P16333 RIMS3 UniProtKB UniProtKB {GO:0030054=GO_REF:0000037, GO:0042391=GO_REF:0000019, GO:0006836=GO_REF:0000037, GO:0045202=GO_REF:0000039, GO:0006887=GO_REF:0000037, GO:0044325=GO_REF:0000019} Q9UJD0 Regulating synaptic membrane exocytosis protein 3 protein 20130413 {GO:0030054=IEA, GO:0042391=IEA, GO:0006836=IEA, GO:0045202=IEA, GO:0006887=IEA, GO:0044325=IEA} exocytosis, neurotransmitter transport, regulation of membrane potential cell junction, synapse ion channel binding Human UniProtKB-SubCell:SL-0258 RIMS4 UniProtKB UniProtKB {GO:0030054=GO_REF:0000037, GO:0006836=GO_REF:0000037, GO:0045202=GO_REF:0000039, GO:0006887=GO_REF:0000037} Q9H426 Regulating synaptic membrane exocytosis protein 4 protein 20130413 {GO:0030054=IEA, GO:0006836=IEA, GO:0045202=IEA, GO:0006887=IEA} exocytosis, neurotransmitter transport cell junction, synapse Human UniProtKB-SubCell:SL-0258 RIN1 IntAct UniProtKB {GO:0005515=PMID:15886098, GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0005886=PMID:9144171, GO:0005856=GO_REF:0000039, GO:0006897=GO_REF:0000037, GO:0005096=GO_REF:0000037} Q13671 Ras and Rab interactor 1 protein 20130415 {GO:0005515=IPI, GO:0007165=IEA, GO:0005737=IEA, GO:0005886=TAS, GO:0005856=IEA, GO:0006897=IEA, GO:0005096=IEA} endocytosis, signal transduction cytoplasm, cytoskeleton, plasma membrane GTPase activator activity, protein binding Human UniProtKB:P42684 RIN2 UniProtKB UniProtKB {GO:0017112=PMID:11733506, GO:0007165=GO_REF:0000002, GO:0005083=PMID:1849280, GO:0005737=GO_REF:0000039, GO:0007264=PMID:1849280, GO:0005575=GO_REF:0000015, GO:0006897=GO_REF:0000037, GO:0005096=GO_REF:0000037} Q8WYP3 Ras and Rab interactor 2 protein 20030507 {GO:0017112=NAS, GO:0007165=IEA, GO:0005083=NAS, GO:0005737=IEA, GO:0007264=NAS, GO:0005575=ND, GO:0006897=IEA, GO:0005096=IEA} endocytosis, signal transduction, small GTPase mediated signal transduction cellular_component, cytoplasm GTPase activator activity, Rab guanyl-nucleotide exchange factor activity, small GTPase regulator activity Human RIN3 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0017112=PMID:21586568, GO:0007165=GO_REF:0000002, GO:0017137=PMID:21586568, GO:0016023=GO_REF:0000039, GO:0031410=PMID:21586568, GO:0005769=PMID:21586568, GO:0006897=PMID:11733506, GO:0005096=GO_REF:0000037} Q8TB24 Ras and Rab interactor 3 protein 20130415 {GO:0005515=IPI, GO:0017112=IMP, GO:0007165=IEA, GO:0017137=IDA, GO:0016023=IEA, GO:0031410=IDA, GO:0005769=IDA, GO:0006897=NAS, GO:0005096=IEA} endocytosis, signal transduction cytoplasmic membrane-bounded vesicle, cytoplasmic vesicle, early endosome GTPase activator activity, Rab GTPase binding, Rab guanyl-nucleotide exchange factor activity, protein binding Human UniProtKB:P19174 RING1 HPA UniProtKB {GO:0031519=PMID:16943429, GO:0035102=PMID:19636380, GO:0005515=PMID:22897849, GO:0035518=PMID:16943429, GO:0004842=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0000151=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0048593=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0001739=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0016607=GO_REF:0000039, GO:0003682=GO_REF:0000019, GO:0008270=GO_REF:0000029, GO:0045892=PMID:9199346, GO:0016568=GO_REF:0000029} Q06587 E3 ubiquitin-protein ligase RING1 protein 20080205 {GO:0031519=IDA, GO:0035102=IDA, GO:0005515=IPI, GO:0035518=IDA, GO:0004842=IEA, GO:0005730=IDA, GO:0000151=IEA, GO:0005634=IDA, GO:0048593=IEA, GO:0009952=IEA, GO:0001739=IEA, GO:0006351=IEA, GO:0005737=IDA, GO:0016607=IEA, GO:0003682=IEA, GO:0008270=NAS, GO:0045892=IDA, GO:0016568=NAS} anterior/posterior pattern specification, camera-type eye morphogenesis, chromatin modification, histone H2A monoubiquitination, negative regulation of transcription, DNA-dependent, transcription, DNA-dependent PRC1 complex, PcG protein complex, cytoplasm, nuclear speck, nucleolus, nucleus, sex chromatin, ubiquitin ligase complex chromatin binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human RINT1 HPA UniProtKB {GO:0005515=PMID:15272311, GO:0005737=GO_REF:0000052, GO:0005783=PMID:15029241, GO:0031572=PMID:11096100, GO:0005789=GO_REF:0000039, GO:0016192=GO_REF:0000037, GO:0015031=GO_REF:0000037} Q6NUQ1 RAD50-interacting protein 1 protein 20100326 {GO:0005515=IPI, GO:0005737=IDA, GO:0005783=IDA, GO:0031572=IMP, GO:0005789=IEA, GO:0016192=IEA, GO:0015031=IEA} G2 DNA damage checkpoint, protein transport, vesicle-mediated transport cytoplasm, endoplasmic reticulum, endoplasmic reticulum membrane protein binding Human RIOK1 UniProtKB UniProtKB {GO:0004674=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q9BRS2 Serine/threonine-protein kinase RIO1 protein 20130413 {GO:0004674=IEA, GO:0005524=IEA} ATP binding, protein serine/threonine kinase activity Human UniProtKB-KW:KW-0067 RIOK2 UniProtKB UniProtKB {GO:0004674=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q9BVS4 Serine/threonine-protein kinase RIO2 protein 20130413 {GO:0004674=IEA, GO:0005524=IEA} ATP binding, protein serine/threonine kinase activity Human UniProtKB-KW:KW-0067 RIOK3 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0007059=PMID:9602165, GO:0004674=GO_REF:0000037, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000037} O14730 Serine/threonine-protein kinase RIO3 protein 20130415 {GO:0005515=IPI, GO:0007059=TAS, GO:0004674=IEA, GO:0003824=IEA, GO:0005524=IEA} chromosome segregation ATP binding, catalytic activity, protein binding, protein serine/threonine kinase activity Human UniProtKB:Q92851 RIPK1 BHF-UCL UniProtKB {GO:0005515=PMID:16127453, GO:0034142=Reactome:REACT_6894, GO:0060555=PMID:11101870, GO:0031264=PMID:11101870, GO:0046330=PMID:17389591, GO:0051291=GO_REF:0000019, GO:0032757=PMID:16127453, GO:0042802=PMID:22817896, GO:0005829=Reactome:REACT_150447, GO:0005739=PMID:16507998, GO:0070513=PMID:8612133, GO:0002756=Reactome:REACT_6809, GO:0005737=GO_REF:0000052, GO:0046777=PMID:8612133, GO:0051092=PMID:8612133, GO:0045944=PMID:16127453, GO:0071356=PMID:17389591, GO:0070926=PMID:16507998, GO:0051260=PMID:22817896, GO:0032481=Reactome:REACT_118823, GO:0044257=PMID:17389591, GO:0043123=PMID:17389591, GO:0034138=Reactome:REACT_6783, GO:0010940=PMID:16507998, GO:0043066=PMID:17979836, GO:0043065=PMID:17389591, GO:0032760=PMID:16127453, GO:0006919=Reactome:REACT_1503, GO:0006915=PMID:7538908, GO:2001243=GO_REF:0000019, GO:0006917=PMID:8612133, GO:0005123=PMID:7538908, GO:0007257=PMID:17979836, GO:0002224=Reactome:REACT_6966, GO:0097190=Reactome:REACT_1619, GO:0005524=GO_REF:0000037, GO:0033209=PMID:8612133, GO:0043235=PMID:8612133, GO:0007165=PMID:8612133, GO:0004672=PMID:15001576, GO:0004674=PMID:8612133, GO:0045087=Reactome:REACT_6802, GO:0001934=PMID:17389591, GO:0034612=PMID:10521396, GO:0045121=GO_REF:0000019, GO:0035666=Reactome:REACT_25281, GO:2000379=PMID:17979836} Q13546 Receptor-interacting serine/threonine-protein kinase 1 protein 20100524 {GO:0005515=IPI, GO:0034142=TAS, GO:0060555=IMP, GO:0031264=IDA, GO:0046330=IDA, GO:0051291=IEA, GO:0032757=IDA, GO:0042802=IPI, GO:0005829=TAS, GO:0005739=IDA, GO:0070513=IPI, GO:0002756=TAS, GO:0005737=IDA, GO:0046777=IDA, GO:0051092=IMP, GO:0045944=IDA, GO:0071356=IDA, GO:0070926=IMP, GO:0051260=IDA, GO:0032481=TAS, GO:0044257=IDA, GO:0043123=IDA, GO:0034138=TAS, GO:0010940=IMP, GO:0043066=TAS, GO:0043065=IDA, GO:0032760=IDA, GO:0006919=TAS, GO:0006915=IDA, GO:2001243=IEA, GO:0006917=IMP, GO:0005123=IPI, GO:0007257=TAS, GO:0002224=TAS, GO:0097190=TAS, GO:0005524=IEA, GO:0033209=IC, GO:0043235=IDA, GO:0007165=TAS, GO:0004672=IDA, GO:0004674=IDA, GO:0045087=TAS, GO:0001934=IMP, GO:0034612=IMP, GO:0045121=IEA, GO:0035666=TAS, GO:2000379=TAS} MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, activation of JUN kinase activity, activation of cysteine-type endopeptidase activity involved in apoptotic process, activation of necroptosis by extracellular signals, apoptotic process, apoptotic signaling pathway, cellular protein catabolic process, cellular response to tumor necrosis factor, induction of apoptosis, innate immune response, negative regulation of apoptotic process, negative regulation of intrinsic apoptotic signaling pathway, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of JNK cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of apoptotic process, positive regulation of interleukin-8 production, positive regulation of necrotic cell death, positive regulation of protein phosphorylation, positive regulation of reactive oxygen species metabolic process, positive regulation of transcription from RNA polymerase II promoter, positive regulation of tumor necrosis factor production, positive regulation of type I interferon production, protein autophosphorylation, protein heterooligomerization, protein homooligomerization, regulation of ATP:ADP antiporter activity, response to tumor necrosis factor, signal transduction, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor signaling pathway, tumor necrosis factor-mediated signaling pathway cytoplasm, cytosol, death-inducing signaling complex, membrane raft, mitochondrion, receptor complex ATP binding, death domain binding, death receptor binding, identical protein binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human RIPK2 BHF-UCL UniProtKB {GO:0005515=PMID:19337385, GO:0032755=GO_REF:0000019, GO:0050830=GO_REF:0000019, GO:0046330=GO_REF:0000019, GO:0007249=GO_REF:0000024, GO:0051403=Reactome:REACT_21308, GO:0042803=PMID:19337385, GO:0002756=Reactome:REACT_6809, GO:0002755=Reactome:REACT_27215, GO:0031398=PMID:15620648, GO:0070671=GO_REF:0000019, GO:0046641=GO_REF:0000019, GO:0070374=GO_REF:0000019, GO:0070673=GO_REF:0000019, GO:0043123=PMID:10329646, GO:0031663=GO_REF:0000019, GO:0032729=GO_REF:0000019, GO:0050700=PMID:10329646, GO:0032728=PMID:22412986, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0032760=GO_REF:0000019, GO:0032727=PMID:22412986, GO:0034134=Reactome:REACT_7980, GO:0070431=GO_REF:0000019, GO:0032722=GO_REF:0000019, GO:0002224=Reactome:REACT_9020, GO:0045087=Reactome:REACT_6802, GO:0035666=Reactome:REACT_25281, GO:0034166=Reactome:REACT_9027, GO:0034162=Reactome:REACT_9047, GO:0050852=Reactome:REACT_12526, GO:0034142=Reactome:REACT_6894, GO:0070423=Reactome:REACT_75776, GO:0032735=PMID:22412986, GO:0070427=GO_REF:0000019, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_75924, GO:0000187=Reactome:REACT_21399, GO:0005737=GO_REF:0000052, GO:0051092=Reactome:REACT_21281, GO:0006954=PMID:9705938, GO:0042098=GO_REF:0000019, GO:0001961=GO_REF:0000019, GO:0002827=GO_REF:0000019, GO:0030274=PMID:15657077, GO:0004871=PMID:9642260, GO:0034138=Reactome:REACT_6783, GO:0070555=GO_REF:0000019, GO:0048011=Reactome:REACT_13776, GO:0043066=Reactome:REACT_13537, GO:0043065=GO_REF:0000019, GO:0032743=GO_REF:0000019, GO:0007254=Reactome:REACT_21368, GO:0006915=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0033091=GO_REF:0000019, GO:0002250=GO_REF:0000024, GO:0007165=PMID:9642260, GO:0071223=GO_REF:0000019, GO:0004674=GO_REF:0000037, GO:0045627=GO_REF:0000019, GO:0034146=Reactome:REACT_9061, GO:0004715=GO_REF:0000003, GO:0071224=GO_REF:0000019, GO:0043330=GO_REF:0000019} O43353 Receptor-interacting serine/threonine-protein kinase 2 protein 20121127 {GO:0005515=IPI, GO:0032755=IEA, GO:0050830=IEA, GO:0046330=IEA, GO:0007249=ISS, GO:0051403=TAS, GO:0042803=IDA, GO:0002756=TAS, GO:0002755=TAS, GO:0031398=IMP, GO:0070671=IEA, GO:0046641=IEA, GO:0070374=IEA, GO:0070673=IEA, GO:0043123=IDA, GO:0031663=IEA, GO:0032729=IEA, GO:0050700=IDA, GO:0032728=NAS, GO:0038124=TAS, GO:0038123=TAS, GO:0032760=IEA, GO:0032727=NAS, GO:0034134=TAS, GO:0070431=IEA, GO:0032722=IEA, GO:0002224=TAS, GO:0045087=TAS, GO:0035666=TAS, GO:0034166=TAS, GO:0034162=TAS, GO:0050852=TAS, GO:0034142=TAS, GO:0070423=TAS, GO:0032735=NAS, GO:0070427=IEA, GO:0035872=TAS, GO:0005829=TAS, GO:0000187=TAS, GO:0005737=IDA, GO:0051092=TAS, GO:0006954=TAS, GO:0042098=IEA, GO:0001961=IEA, GO:0002827=IEA, GO:0030274=IPI, GO:0004871=TAS, GO:0034138=TAS, GO:0070555=IEA, GO:0048011=TAS, GO:0043066=TAS, GO:0043065=IEA, GO:0032743=IEA, GO:0007254=TAS, GO:0006915=IEA, GO:0005524=IEA, GO:0033091=IEA, GO:0002250=ISS, GO:0007165=TAS, GO:0071223=IEA, GO:0004674=IEA, GO:0045627=IEA, GO:0034146=TAS, GO:0004715=IEA, GO:0071224=IEA, GO:0043330=IEA} I-kappaB kinase/NF-kappaB cascade, JNK cascade, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, T cell proliferation, T cell receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, activation of MAPK activity, adaptive immune response, apoptotic process, cellular response to lipoteichoic acid, cellular response to peptidoglycan, defense response to Gram-positive bacterium, inflammatory response, innate immune response, lipopolysaccharide-mediated signaling pathway, negative regulation of apoptotic process, neurotrophin TRK receptor signaling pathway, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, nucleotide-binding oligomerization domain containing 1 signaling pathway, nucleotide-binding oligomerization domain containing 2 signaling pathway, nucleotide-binding oligomerization domain containing signaling pathway, positive regulation of ERK1 and ERK2 cascade, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of JNK cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of T-helper 1 cell differentiation, positive regulation of T-helper 1 type immune response, positive regulation of alpha-beta T cell proliferation, positive regulation of apoptotic process, positive regulation of chemokine production, positive regulation of cytokine-mediated signaling pathway, positive regulation of immature T cell proliferation, positive regulation of interferon-alpha production, positive regulation of interferon-beta production, positive regulation of interferon-gamma production, positive regulation of interleukin-12 production, positive regulation of interleukin-2 production, positive regulation of interleukin-6 production, positive regulation of protein ubiquitination, positive regulation of tumor necrosis factor production, response to exogenous dsRNA, response to interleukin-1, response to interleukin-12, response to interleukin-18, signal transduction, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway cytoplasm, cytosol ATP binding, CARD domain binding, LIM domain binding, non-membrane spanning protein tyrosine kinase activity, protein binding, protein homodimerization activity, protein serine/threonine kinase activity, signal transducer activity Human RIPK3 IntAct UniProtKB {GO:0005515=PMID:23201684, GO:0034142=Reactome:REACT_6894, GO:0005886=GO_REF:0000039, GO:0003713=PMID:10339433, GO:0007249=GO_REF:0000019, GO:0006917=GO_REF:0000019, GO:0002224=Reactome:REACT_6966, GO:0005524=GO_REF:0000037, GO:0097190=PMID:10339433, GO:0042802=PMID:22817896, GO:0005829=Reactome:REACT_150365, GO:0005739=GO_REF:0000039, GO:0002756=Reactome:REACT_6809, GO:0007165=PMID:10339433, GO:0004704=GO_REF:0000019, GO:0004672=PMID:10358032, GO:0004674=PMID:10339433, GO:0045087=Reactome:REACT_6802, GO:0035666=Reactome:REACT_25281, GO:0032481=Reactome:REACT_118823, GO:0051260=PMID:22817896, GO:0034138=Reactome:REACT_6783, GO:0006464=PMID:10358032} Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 protein 20130415 {GO:0005515=IPI, GO:0034142=TAS, GO:0005886=IEA, GO:0003713=TAS, GO:0007249=IEA, GO:0006917=IEA, GO:0002224=TAS, GO:0005524=IEA, GO:0097190=TAS, GO:0042802=IPI, GO:0005829=TAS, GO:0005739=IEA, GO:0002756=TAS, GO:0007165=TAS, GO:0004704=IEA, GO:0004672=TAS, GO:0004674=TAS, GO:0045087=TAS, GO:0035666=TAS, GO:0032481=TAS, GO:0051260=IDA, GO:0034138=TAS, GO:0006464=TAS} I-kappaB kinase/NF-kappaB cascade, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, apoptotic signaling pathway, cellular protein modification process, induction of apoptosis, innate immune response, positive regulation of type I interferon production, protein homooligomerization, signal transduction, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor signaling pathway cytosol, mitochondrion, plasma membrane ATP binding, NF-kappaB-inducing kinase activity, identical protein binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, transcription coactivator activity Human UniProtKB:Q9Y572 RIPK4 IntAct UniProtKB {GO:0005515=PMID:21931591, GO:0005737=GO_REF:0000024, GO:0016020=GO_REF:0000039, GO:0004674=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0002009=PMID:22197488, GO:0005524=GO_REF:0000037} P57078 Receptor-interacting serine/threonine-protein kinase 4 protein 20130415 {GO:0005515=IPI, GO:0005737=ISS, GO:0016020=IEA, GO:0004674=IEA, GO:0005634=IDA, GO:0002009=IMP, GO:0005524=IEA} morphogenesis of an epithelium cytoplasm, membrane, nucleus ATP binding, protein binding, protein serine/threonine kinase activity Human UniProtKB:Q13490 RIT1 IntAct UniProtKB {GO:0005515=PMID:10545207, GO:0007165=PMID:8918462, GO:0005516=PMID:8918462, GO:0048011=Reactome:REACT_11061, GO:0005886=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0007264=Reactome:REACT_12077, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000019} Q92963 GTP-binding protein Rit1 protein 20130415 {GO:0005515=IPI, GO:0007165=TAS, GO:0005516=TAS, GO:0048011=TAS, GO:0005886=IEA, GO:0016020=IEA, GO:0007264=TAS, GO:0003924=IEA, GO:0005525=IEA} neurotrophin TRK receptor signaling pathway, signal transduction, small GTPase mediated signal transduction membrane, plasma membrane GTP binding, GTPase activity, calmodulin binding, protein binding Human UniProtKB:Q13129 RIT2 Reactome UniProtKB {GO:0007165=PMID:8918462, GO:0005516=GO_REF:0000037, GO:0048011=Reactome:REACT_11061, GO:0005886=PMID:8824319, GO:0016020=GO_REF:0000002, GO:0007264=Reactome:REACT_12077, GO:0003924=PMID:8824319, GO:0007268=PMID:8918462, GO:0005634=GO_REF:0000039, GO:0005525=GO_REF:0000037} Q99578 GTP-binding protein Rit2 protein 20130301 {GO:0007165=TAS, GO:0005516=IEA, GO:0048011=TAS, GO:0005886=TAS, GO:0016020=IEA, GO:0007264=TAS, GO:0003924=NAS, GO:0007268=TAS, GO:0005634=IEA, GO:0005525=IEA} neurotrophin TRK receptor signaling pathway, signal transduction, small GTPase mediated signal transduction, synaptic transmission membrane, nucleus, plasma membrane GTP binding, GTPase activity, calmodulin binding Human RLBP1 Reactome UniProtKB {GO:0005502=GO_REF:0000019, GO:0005622=GO_REF:0000002, GO:0005215=GO_REF:0000002, GO:0007603=Reactome:REACT_160125, GO:0006776=PMID:9326942, GO:0005575=GO_REF:0000015, GO:0001523=Reactome:REACT_160156, GO:0019841=GO_REF:0000037, GO:0007601=GO_REF:0000037, GO:0044297=GO_REF:0000019, GO:0005829=Reactome:REACT_160302} P12271 Retinaldehyde-binding protein 1 protein 20130116 {GO:0005502=IEA, GO:0005622=IEA, GO:0005215=IEA, GO:0007603=TAS, GO:0006776=TAS, GO:0005575=ND, GO:0001523=TAS, GO:0019841=IEA, GO:0007601=IEA, GO:0044297=IEA, GO:0005829=TAS} phototransduction, visible light, retinoid metabolic process, visual perception, vitamin A metabolic process cell body, cellular_component, cytosol, intracellular 11-cis retinal binding, retinol binding, transporter activity Human RLF IntAct UniProtKB {GO:0005515=PMID:10545207, GO:0051276=PMID:1649386, GO:0006355=PMID:8545128, GO:0045944=PMID:8545128, GO:0015074=PMID:1851085, GO:0005634=PMID:8545128, GO:0008270=GO_REF:0000002, GO:0045893=PMID:8545128, GO:0003677=PMID:8545128, GO:0009294=PMID:8545128, GO:0006351=GO_REF:0000037} Q13129 Zinc finger protein Rlf protein 20130415 {GO:0005515=IPI, GO:0051276=IDA, GO:0006355=NAS, GO:0045944=ISS, GO:0015074=IDA, GO:0005634=IC, GO:0008270=IEA, GO:0045893=ISS, GO:0003677=NAS, GO:0009294=NAS, GO:0006351=IEA} DNA integration, DNA mediated transformation, chromosome organization, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, protein binding, zinc ion binding Human UniProtKB:Q92963 RLIM HPA UniProtKB {GO:0006511=GO_REF:0000024, GO:0004842=GO_REF:0000024, GO:0016567=GO_REF:0000024, GO:0003714=PMID:11013082, GO:0005634=GO_REF:0000052, GO:0000122=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0043433=GO_REF:0000019, GO:0060816=PMID:19945382, GO:0005737=GO_REF:0000052, GO:0017053=PMID:11013082, GO:0008270=GO_REF:0000002, GO:0045892=PMID:11013082} Q9NVW2 E3 ubiquitin-protein ligase RLIM protein 20090616 {GO:0006511=ISS, GO:0004842=ISS, GO:0016567=ISS, GO:0003714=NAS, GO:0005634=IDA, GO:0000122=IEA, GO:0006351=IEA, GO:0043433=IEA, GO:0060816=IDA, GO:0005737=IDA, GO:0017053=NAS, GO:0008270=IEA, GO:0045892=NAS} negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, protein ubiquitination, random inactivation of X chromosome, transcription, DNA-dependent, ubiquitin-dependent protein catabolic process cytoplasm, nucleus, transcriptional repressor complex transcription corepressor activity, ubiquitin-protein ligase activity, zinc ion binding Human RLN1 PINC UniProtKB {GO:0007165=PMID:6298628, GO:0007565=PMID:6298628, GO:0005179=GO_REF:0000037, GO:0005576=GO_REF:0000039} P04808 Prorelaxin H1 protein 20040811 {GO:0007165=NAS, GO:0007565=NAS, GO:0005179=IEA, GO:0005576=IEA} female pregnancy, signal transduction extracellular region hormone activity Human RLN2 Reactome UniProtKB {GO:0007565=PMID:6548702, GO:0005179=GO_REF:0000037, GO:0005576=Reactome:REACT_22268} P04090 Prorelaxin H2 protein 20091027 {GO:0007565=TAS, GO:0005179=IEA, GO:0005576=TAS} female pregnancy extracellular region hormone activity Human RLN3 Reactome UniProtKB {GO:0001664=GO_REF:0000019, GO:0005179=GO_REF:0000037, GO:0005576=Reactome:REACT_22289} Q8WXF3 Relaxin-3 protein 20091026 {GO:0001664=IEA, GO:0005179=IEA, GO:0005576=TAS} extracellular region G-protein coupled receptor binding, hormone activity Human RLTPR null null {} null null null null {} null null null RMI1 IntAct UniProtKB {GO:0005515=PMID:20360068, GO:0006260=GO_REF:0000037, GO:0005634=GO_REF:0000039} Q9H9A7 RecQ-mediated genome instability protein 1 protein 20130415 {GO:0005515=IPI, GO:0006260=IEA, GO:0005634=IEA} DNA replication nucleus protein binding Human UniProtKB:P54132 RMI2 HPA UniProtKB {GO:0006260=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037} Q96E14 RecQ-mediated genome instability protein 2 protein 20111111 {GO:0006260=IEA, GO:0005737=IDA, GO:0005634=IDA, GO:0003677=IEA} DNA replication cytoplasm, nucleus DNA binding Human RMND1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0006412=GO_REF:0000037} Q9NWS8 Required for meiotic nuclear division protein 1 homolog protein 20130413 {GO:0005739=IEA, GO:0006412=IEA} translation mitochondrion Human UniProtKB-SubCell:SL-0173 RMND5A null null {} null null null null {} null null null RMND5B null null {} null null null null {} null null null RNASE1 IntAct UniProtKB {GO:0005515=PMID:17350650, GO:0005576=GO_REF:0000039, GO:0004522=GO_REF:0000003, GO:0003676=GO_REF:0000002} P07998 Ribonuclease pancreatic protein 20130415 {GO:0005515=IPI, GO:0005576=IEA, GO:0004522=IEA, GO:0003676=IEA} extracellular region nucleic acid binding, pancreatic ribonuclease activity, protein binding Human UniProtKB:P13489 RNASE11 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039, GO:0004522=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q8TAA1 Probable ribonuclease 11 protein 20130413 {GO:0005576=IEA, GO:0004522=IEA, GO:0003676=IEA} extracellular region nucleic acid binding, pancreatic ribonuclease activity Human UniProtKB-SubCell:SL-0243 RNASE2 PINC UniProtKB {GO:0006935=PMID:12855582, GO:0005576=PMID:2734298, GO:0004540=PMID:2734298, GO:0004522=GO_REF:0000003, GO:0003676=GO_REF:0000002, GO:0005764=GO_REF:0000039, GO:0006401=PMID:2734298} P10153 Non-secretory ribonuclease protein 20030904 {GO:0006935=IDA, GO:0005576=TAS, GO:0004540=TAS, GO:0004522=IEA, GO:0003676=IEA, GO:0005764=IEA, GO:0006401=TAS} RNA catabolic process, chemotaxis extracellular region, lysosome nucleic acid binding, pancreatic ribonuclease activity, ribonuclease activity Human RNASE3 PINC UniProtKB {GO:0004540=PMID:2745977, GO:0005576=GO_REF:0000039, GO:0004522=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0042742=GO_REF:0000037, GO:0006401=PMID:2745977} P12724 Eosinophil cationic protein protein 20030904 {GO:0004540=TAS, GO:0005576=IEA, GO:0004522=IEA, GO:0003676=IEA, GO:0042742=IEA, GO:0006401=TAS} RNA catabolic process, defense response to bacterium extracellular region nucleic acid binding, pancreatic ribonuclease activity, ribonuclease activity Human RNASE6 PINC UniProtKB {GO:0004540=PMID:8836175, GO:0006952=PMID:8836175, GO:0005576=GO_REF:0000039, GO:0004522=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0006401=PMID:8836175} Q93091 Ribonuclease K6 protein 20030904 {GO:0004540=TAS, GO:0006952=TAS, GO:0005576=IEA, GO:0004522=IEA, GO:0003676=IEA, GO:0006401=TAS} RNA catabolic process, defense response extracellular region nucleic acid binding, pancreatic ribonuclease activity, ribonuclease activity Human RNASE7 UniProtKB UniProtKB {GO:0009617=PMID:12244054, GO:0045087=PMID:12244054, GO:0005576=PMID:12244054, GO:0004540=PMID:12244054, GO:0004522=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0042742=GO_REF:0000037} Q9H1E1 Ribonuclease 7 protein 20031104 {GO:0009617=NAS, GO:0045087=NAS, GO:0005576=NAS, GO:0004540=IDA, GO:0004522=IEA, GO:0003676=IEA, GO:0042742=IEA} defense response to bacterium, innate immune response, response to bacterium extracellular region nucleic acid binding, pancreatic ribonuclease activity, ribonuclease activity Human RNASEH1 PINC UniProtKB {GO:0005739=GO_REF:0000019, GO:0000287=GO_REF:0000002, GO:0003723=PMID:9799596, GO:0004523=GO_REF:0000003, GO:0004540=PMID:9799596, GO:0005634=GO_REF:0000019, GO:0003676=PMID:9799596, GO:0006264=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0006401=PMID:9799596} O60930 Ribonuclease H1 protein 20030904 {GO:0005739=IEA, GO:0000287=IEA, GO:0003723=TAS, GO:0004523=IEA, GO:0004540=TAS, GO:0005634=IEA, GO:0003676=TAS, GO:0006264=IEA, GO:0042803=IEA, GO:0006401=TAS} RNA catabolic process, mitochondrial DNA replication mitochondrion, nucleus RNA binding, magnesium ion binding, nucleic acid binding, protein homodimerization activity, ribonuclease H activity, ribonuclease activity Human RNASEH2A PINC UniProtKB {GO:0032299=PMID:21177858, GO:0006260=PMID:21177858, GO:0004523=PMID:21177858, GO:0003723=GO_REF:0000002, GO:0004540=PMID:9789007, GO:0005634=GO_REF:0000039, GO:0046872=GO_REF:0000037, GO:0006401=PMID:21177858} O75792 Ribonuclease H2 subunit A protein 20030904 {GO:0032299=IDA, GO:0006260=TAS, GO:0004523=IDA, GO:0003723=IEA, GO:0004540=TAS, GO:0005634=IEA, GO:0046872=IEA, GO:0006401=IDA} DNA replication, RNA catabolic process nucleus, ribonuclease H2 complex RNA binding, metal ion binding, ribonuclease H activity, ribonuclease activity Human RNASEH2B HPA UniProtKB {GO:0032299=PMID:21177858, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006401=PMID:21177858} Q5TBB1 Ribonuclease H2 subunit B protein 20110516 {GO:0032299=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0006401=IDA} RNA catabolic process nucleolus, nucleus, ribonuclease H2 complex NOT Human RNASEH2C UniProtKB UniProtKB {GO:0032299=PMID:21177858, GO:0005634=GO_REF:0000039, GO:0006401=PMID:21177858} Q8TDP1 Ribonuclease H2 subunit C protein 20110202 {GO:0032299=IDA, GO:0005634=IEA, GO:0006401=IDA} RNA catabolic process nucleus, ribonuclease H2 complex Human RNASEK UniProtKB UniProtKB {GO:0009303=PMID:17881363, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037, GO:0004521=PMID:17881363} Q6P5S7 Ribonuclease kappa protein 20080804 {GO:0009303=IDA, GO:0005575=ND, GO:0016021=IEA, GO:0004521=IDA} rRNA transcription cellular_component, integral to membrane endoribonuclease activity Human RNASEL Reactome UniProtKB {GO:0006397=GO_REF:0000002, GO:0003723=PMID:7514601, GO:0019221=Reactome:REACT_25229, GO:0004521=PMID:7514601, GO:0005575=GO_REF:0000015, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_25192, GO:0005739=GO_REF:0000039, GO:0051607=PMID:19923450, GO:0060337=Reactome:REACT_25162, GO:0004672=GO_REF:0000002, GO:0045944=PMID:19245366, GO:0006468=PMID:7514601, GO:0045071=PMID:19923450} Q05823 2-5A-dependent ribonuclease protein 20101115 {GO:0006397=IEA, GO:0003723=IDA, GO:0019221=TAS, GO:0004521=NAS, GO:0005575=ND, GO:0005524=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0051607=IDA, GO:0060337=TAS, GO:0004672=IEA, GO:0045944=IDA, GO:0006468=NAS, GO:0045071=IDA} cytokine-mediated signaling pathway, defense response to virus, mRNA processing, negative regulation of viral genome replication, positive regulation of transcription from RNA polymerase II promoter, protein phosphorylation, type I interferon-mediated signaling pathway cellular_component, cytosol, mitochondrion ATP binding, RNA binding, endoribonuclease activity, metal ion binding, protein kinase activity Human RNASET2 UniProtKB UniProtKB {GO:0003723=GO_REF:0000002, GO:0005788=PMID:16620762, GO:0033897=GO_REF:0000002, GO:0004540=PMID:22735700, GO:0005576=PMID:9192857, GO:0005764=PMID:16620762, GO:0005615=PMID:16620762, GO:0006401=PMID:22735700, GO:0043202=GO_REF:0000039} O00584 Ribonuclease T2 protein 20120921 {GO:0003723=IEA, GO:0005788=IDA, GO:0033897=IEA, GO:0004540=IDA, GO:0005576=TAS, GO:0005764=IDA, GO:0005615=IDA, GO:0006401=IDA, GO:0043202=IEA} RNA catabolic process endoplasmic reticulum lumen, extracellular region, extracellular space, lysosomal lumen, lysosome RNA binding, ribonuclease T2 activity, ribonuclease activity Human RND1 GOC UniProtKB {GO:0005515=PMID:10664463, GO:0005886=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0003924=PMID:11095956, GO:0005102=PMID:19843518, GO:0005525=GO_REF:0000037, GO:0005829=Reactome:REACT_19382, GO:0006184=PMID:9531558, GO:0016322=PMID:11095956, GO:0007162=PMID:9531558, GO:0005912=PMID:9531558, GO:0007411=Reactome:REACT_18266, GO:0007015=PMID:9531558, GO:0005856=GO_REF:0000039} Q92730 Rho-related GTP-binding protein Rho6 protein 20130413 {GO:0005515=IPI, GO:0005886=IEA, GO:0007264=IEA, GO:0003924=NAS, GO:0005102=IPI, GO:0005525=IEA, GO:0005829=TAS, GO:0006184=NAS, GO:0016322=IDA, GO:0007162=IDA, GO:0005912=IDA, GO:0007411=TAS, GO:0007015=IDA, GO:0005856=IEA} GTP catabolic process, actin filament organization, axon guidance, negative regulation of cell adhesion, neuron remodeling, small GTPase mediated signal transduction adherens junction, cytoskeleton, cytosol, plasma membrane GTP binding, GTPase activity, protein binding, receptor binding Human RND2 GOC UniProtKB {GO:0006184=PMID:8938427, GO:0005515=PMID:14732713, GO:0005622=GO_REF:0000002, GO:0007165=PMID:8938427, GO:0047485=GO_REF:0000019, GO:0016020=GO_REF:0000038, GO:0007264=GO_REF:0000002, GO:0003924=PMID:8938427, GO:0005525=GO_REF:0000037, GO:0002080=GO_REF:0000039, GO:0005769=GO_REF:0000019} P52198 Rho-related GTP-binding protein RhoN protein 20130413 {GO:0006184=TAS, GO:0005515=IPI, GO:0005622=IEA, GO:0007165=TAS, GO:0047485=IEA, GO:0016020=IEA, GO:0007264=IEA, GO:0003924=TAS, GO:0005525=IEA, GO:0002080=IEA, GO:0005769=IEA} GTP catabolic process, signal transduction, small GTPase mediated signal transduction acrosomal membrane, early endosome, intracellular, membrane GTP binding, GTPase activity, protein N-terminus binding, protein binding Human RND3 GOC UniProtKB {GO:0006184=PMID:8649376, GO:0030036=PMID:9531558, GO:0000139=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0003924=PMID:8649376, GO:0007155=PMID:9531558, GO:0005525=GO_REF:0000037} P61587 Rho-related GTP-binding protein RhoE protein 20130413 {GO:0006184=TAS, GO:0030036=TAS, GO:0000139=IEA, GO:0007264=IEA, GO:0003924=TAS, GO:0007155=TAS, GO:0005525=IEA} GTP catabolic process, actin cytoskeleton organization, cell adhesion, small GTPase mediated signal transduction Golgi membrane GTP binding, GTPase activity Human RNF10 UniProtKB UniProtKB {GO:0005515=PMID:16335786, GO:0005737=PMID:16335786, GO:0010626=GO_REF:0000024, GO:0044212=GO_REF:0000024, GO:0045944=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000024, GO:0045893=PMID:16335786, GO:0006351=GO_REF:0000037, GO:0031643=GO_REF:0000024} Q8N5U6 RING finger protein 10 protein 20100408 {GO:0005515=IPI, GO:0005737=IDA, GO:0010626=ISS, GO:0044212=ISS, GO:0045944=ISS, GO:0008270=IEA, GO:0005634=ISS, GO:0045893=IDA, GO:0006351=IEA, GO:0031643=ISS} negative regulation of Schwann cell proliferation, positive regulation of myelination, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus protein binding, transcription regulatory region DNA binding, zinc ion binding Human UniProtKB:Q5XI59 RNF103 PINC UniProtKB {GO:0005515=PMID:18675248, GO:0004842=PMID:10500182, GO:0016567=PMID:10500182, GO:0005783=PMID:18675248, GO:0005789=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007417=PMID:9070305, GO:0030433=PMID:18675248} O00237 E3 ubiquitin-protein ligase RNF103 protein 20030904 {GO:0005515=IPI, GO:0004842=IDA, GO:0016567=IDA, GO:0005783=IDA, GO:0005789=IEA, GO:0008270=IEA, GO:0016021=IEA, GO:0007417=TAS, GO:0030433=IDA} ER-associated protein catabolic process, central nervous system development, protein ubiquitination endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane protein binding, ubiquitin-protein ligase activity, zinc ion binding Human RNF11 IntAct UniProtKB {GO:0005515=PMID:20676133, GO:0042787=PMID:14755250, GO:0000151=PMID:14755250, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0055037=GO_REF:0000039, GO:0003677=PMID:10673045, GO:0005769=GO_REF:0000039} Q9Y3C5 RING finger protein 11 protein 20130415 {GO:0005515=IPI, GO:0042787=IDA, GO:0000151=IDA, GO:0005634=IEA, GO:0008270=IEA, GO:0055037=IEA, GO:0003677=TAS, GO:0005769=IEA} protein ubiquitination involved in ubiquitin-dependent protein catabolic process early endosome, nucleus, recycling endosome, ubiquitin ligase complex DNA binding, protein binding, zinc ion binding Human UniProtKB:Q9UJY5 RNF111 HPA UniProtKB {GO:0005515=PMID:16601693, GO:0000209=GO_REF:0000019, GO:0010467=Reactome:REACT_71, GO:0007389=GO_REF:0000019, GO:0004842=PMID:16601693, GO:0006367=Reactome:REACT_12627, GO:0032184=PMID:23086935, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0046332=GO_REF:0000019, GO:0006351=Reactome:REACT_121061, GO:0043234=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0045944=Reactome:REACT_120734, GO:0031398=GO_REF:0000019, GO:0005654=Reactome:REACT_121185, GO:0008270=GO_REF:0000002, GO:0007179=Reactome:REACT_6844, GO:0030579=GO_REF:0000019, GO:0045893=PMID:16601693, GO:0030511=GO_REF:0000019} Q6ZNA4 E3 ubiquitin-protein ligase Arkadia protein 20111111 {GO:0005515=IPI, GO:0000209=IEA, GO:0010467=TAS, GO:0007389=IEA, GO:0004842=IMP, GO:0006367=TAS, GO:0032184=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0046332=IEA, GO:0006351=TAS, GO:0043234=IEA, GO:0005737=IDA, GO:0045944=TAS, GO:0031398=IEA, GO:0005654=TAS, GO:0008270=IEA, GO:0007179=TAS, GO:0030579=IEA, GO:0045893=IMP, GO:0030511=IEA} gene expression, pattern specification process, positive regulation of protein ubiquitination, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of transforming growth factor beta receptor signaling pathway, protein polyubiquitination, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, ubiquitin-dependent SMAD protein catabolic process cytoplasm, nucleolus, nucleoplasm, nucleus, protein complex SMAD binding, SUMO polymer binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human RNF112 UniProtKB UniProtKB {GO:0005737=GO_REF:0000019, GO:0003924=GO_REF:0000002, GO:0005634=GO_REF:0000019, GO:0008270=PMID:8660987, GO:0016021=GO_REF:0000037, GO:0005525=GO_REF:0000002} Q9ULX5 RING finger protein 112 protein 20021105 {GO:0005737=IEA, GO:0003924=IEA, GO:0005634=IEA, GO:0008270=NAS, GO:0016021=IEA, GO:0005525=IEA} cytoplasm, integral to membrane, nucleus GTP binding, GTPase activity, zinc ion binding Human RNF113A InterPro UniProtKB {GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} O15541 RING finger protein 113A protein 20130413 {GO:0008270=IEA, GO:0003676=IEA} nucleic acid binding, zinc ion binding Human InterPro:IPR000571|InterPro:IPR001841 RNF113B InterPro UniProtKB {GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q8IZP6 RING finger protein 113B protein 20130413 {GO:0008270=IEA, GO:0003676=IEA} nucleic acid binding, zinc ion binding Human InterPro:IPR000571|InterPro:IPR001841 RNF114 LIFEdb UniProtKB {GO:0005622=GO_REF:0000054, GO:0007275=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0007283=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q9Y508 RING finger protein 114 protein 20100607 {GO:0005622=IDA, GO:0007275=IEA, GO:0008270=IEA, GO:0007283=IEA, GO:0030154=IEA} cell differentiation, multicellular organismal development, spermatogenesis intracellular zinc ion binding Human RNF115 UniProtKB UniProtKB {GO:0005515=PMID:16925951, GO:0004842=PMID:18819927, GO:0008270=GO_REF:0000002, GO:0051865=PMID:16288031, GO:0005829=GO_REF:0000024} Q9Y4L5 E3 ubiquitin-protein ligase RNF115 protein 20100602 {GO:0005515=IPI, GO:0004842=IDA, GO:0008270=IEA, GO:0051865=IDA, GO:0005829=ISS} protein autoubiquitination cytosol protein binding, ubiquitin-protein ligase activity, zinc ion binding Human RNF122 UniProtKB UniProtKB {GO:0005794=GO_REF:0000039, GO:0005783=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q9H9V4 RING finger protein 122 protein 20130413 {GO:0005794=IEA, GO:0005783=IEA, GO:0008270=IEA, GO:0016021=IEA} Golgi apparatus, endoplasmic reticulum, integral to membrane zinc ion binding Human UniProtKB-SubCell:SL-0132 RNF123 LIFEdb UniProtKB {GO:0005737=GO_REF:0000054, GO:0016567=GO_REF:0000041, GO:0016874=GO_REF:0000037, GO:0008270=GO_REF:0000002} Q5XPI4 E3 ubiquitin-protein ligase RNF123 protein 20100607 {GO:0005737=IDA, GO:0016567=IEA, GO:0016874=IEA, GO:0008270=IEA} protein ubiquitination cytoplasm ligase activity, zinc ion binding Human RNF125 Reactome UniProtKB {GO:0004842=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0008270=GO_REF:0000002, GO:0032480=Reactome:REACT_25271} Q96EQ8 E3 ubiquitin-protein ligase RNF125 protein 20130207 {GO:0004842=IEA, GO:0045087=TAS, GO:0008270=IEA, GO:0032480=TAS} innate immune response, negative regulation of type I interferon production ubiquitin-protein ligase activity, zinc ion binding Human RNF126 IntAct UniProtKB {GO:0005515=PMID:19549727, GO:0008270=GO_REF:0000002} Q9BV68 RING finger protein 126 protein 20130415 {GO:0005515=IPI, GO:0008270=IEA} protein binding, zinc ion binding Human UniProtKB:Q9Y2X8 RNF128 UniProtKB UniProtKB {GO:0042036=GO_REF:0000019, GO:0048471=GO_REF:0000039, GO:0004842=GO_REF:0000019, GO:0005794=GO_REF:0000019, GO:0005783=GO_REF:0000019, GO:0005770=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0012505=GO_REF:0000039} Q8TEB7 E3 ubiquitin-protein ligase RNF128 protein 20130413 {GO:0042036=IEA, GO:0048471=IEA, GO:0004842=IEA, GO:0005794=IEA, GO:0005783=IEA, GO:0005770=IEA, GO:0008270=IEA, GO:0016021=IEA, GO:0012505=IEA} negative regulation of cytokine biosynthetic process Golgi apparatus, endomembrane system, endoplasmic reticulum, integral to membrane, late endosome, perinuclear region of cytoplasm ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB-SubCell:SL-0198 RNF13 UniProtKB UniProtKB {GO:0004842=GO_REF:0000024, GO:0000139=GO_REF:0000039, GO:0031902=GO_REF:0000024, GO:0005789=GO_REF:0000039, GO:0005637=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005765=GO_REF:0000024, GO:0051865=GO_REF:0000024} O43567 E3 ubiquitin-protein ligase RNF13 protein 20100625 {GO:0004842=ISS, GO:0000139=IEA, GO:0031902=ISS, GO:0005789=IEA, GO:0005637=IEA, GO:0008270=IEA, GO:0016021=IEA, GO:0005765=ISS, GO:0051865=ISS} protein autoubiquitination Golgi membrane, endoplasmic reticulum membrane, integral to membrane, late endosome membrane, lysosomal membrane, nuclear inner membrane ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:O54965 RNF130 HPA UniProtKB {GO:0004842=PMID:16549277, GO:0005737=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0012501=PMID:13679316, GO:0016021=GO_REF:0000037} Q86XS8 E3 ubiquitin-protein ligase RNF130 protein 20101115 {GO:0004842=IDA, GO:0005737=IDA, GO:0006915=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0012501=ISS, GO:0016021=IEA} apoptotic process, programmed cell death cytoplasm, integral to membrane, nucleus ubiquitin-protein ligase activity, zinc ion binding Human RNF133 UniProtKB UniProtKB {GO:0016874=GO_REF:0000037, GO:0005789=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0051865=GO_REF:0000019} Q8WVZ7 E3 ubiquitin-protein ligase RNF133 protein 20130413 {GO:0016874=IEA, GO:0005789=IEA, GO:0008270=IEA, GO:0016021=IEA, GO:0051865=IEA} protein autoubiquitination endoplasmic reticulum membrane, integral to membrane ligase activity, zinc ion binding Human UniProtKB-SubCell:SL-0097 RNF135 Reactome UniProtKB {GO:0005515=PMID:19017631, GO:0032728=PMID:19017631, GO:0004842=PMID:19484123, GO:0005737=PMID:19484123, GO:0016567=PMID:19484123, GO:0045087=Reactome:REACT_6802, GO:0045088=PMID:19017631, GO:0043021=PMID:19881509, GO:0008270=GO_REF:0000002, GO:0032480=Reactome:REACT_25271, GO:0005829=Reactome:REACT_25398} Q8IUD6 E3 ubiquitin-protein ligase RNF135 protein 20130301 {GO:0005515=IPI, GO:0032728=IMP, GO:0004842=IDA, GO:0005737=IDA, GO:0016567=IDA, GO:0045087=TAS, GO:0045088=IMP, GO:0043021=IPI, GO:0008270=IEA, GO:0032480=TAS, GO:0005829=TAS} innate immune response, negative regulation of type I interferon production, positive regulation of interferon-beta production, protein ubiquitination, regulation of innate immune response cytoplasm, cytosol protein binding, ribonucleoprotein complex binding, ubiquitin-protein ligase activity, zinc ion binding Human RNF138 UniPathway UniProtKB {GO:0016567=GO_REF:0000041, GO:0019901=PMID:16714285, GO:0016874=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0016055=GO_REF:0000037} Q8WVD3 E3 ubiquitin-protein ligase RNF138 protein 20130413 {GO:0016567=IEA, GO:0019901=IPI, GO:0016874=IEA, GO:0008270=IEA, GO:0016055=IEA} Wnt receptor signaling pathway, protein ubiquitination ligase activity, protein kinase binding, zinc ion binding Human UniPathway:UPA00143 RNF139 IntAct UniProtKB {GO:0017148=PMID:20068067, GO:0005515=PMID:12032852, GO:0004842=PMID:19720873, GO:0008285=PMID:17016439, GO:0016567=PMID:19720873, GO:0060628=PMID:19706601, GO:0005783=PMID:12032852, GO:0016874=PMID:10500182, GO:0070613=PMID:19706601, GO:0019787=PMID:17016439, GO:0005789=GO_REF:0000039, GO:0004872=PMID:9689122, GO:0031396=PMID:10500182, GO:0008270=GO_REF:0000002, GO:0016021=PMID:12032852} Q8WU17 E3 ubiquitin-protein ligase RNF139 protein 20130415 {GO:0017148=IDA, GO:0005515=IPI, GO:0004842=IMP, GO:0008285=IDA, GO:0016567=IMP, GO:0060628=IDA, GO:0005783=IDA, GO:0016874=TAS, GO:0070613=IDA, GO:0019787=IDA, GO:0005789=IEA, GO:0004872=TAS, GO:0031396=IDA, GO:0008270=IEA, GO:0016021=TAS} negative regulation of cell proliferation, negative regulation of translation, protein ubiquitination, regulation of ER to Golgi vesicle-mediated transport, regulation of protein processing, regulation of protein ubiquitination endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane ligase activity, protein binding, receptor activity, small conjugating protein ligase activity, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:P40337 RNF14 HPA UniProtKB {GO:0005515=PMID:19345326, GO:0006355=PMID:19345326, GO:0016567=PMID:11322894, GO:0006357=PMID:10085091, GO:0003713=PMID:15572661, GO:0060765=PMID:19345326, GO:0005634=PMID:11322894, GO:0050681=PMID:19345326, GO:0006351=GO_REF:0000037, GO:0007165=PMID:10085091, GO:0005737=GO_REF:0000052, GO:0019787=PMID:11322894, GO:0008270=GO_REF:0000002, GO:0045893=PMID:19345326, GO:0032355=PMID:15831516, GO:0030521=PMID:15572661} Q9UBS8 E3 ubiquitin-protein ligase RNF14 protein 20081203 {GO:0005515=IPI, GO:0006355=IDA, GO:0016567=IEP, GO:0006357=TAS, GO:0003713=NAS, GO:0060765=IDA, GO:0005634=IDA, GO:0050681=IPI, GO:0006351=IEA, GO:0007165=TAS, GO:0005737=IDA, GO:0019787=IDA, GO:0008270=IEA, GO:0045893=IDA, GO:0032355=IDA, GO:0030521=NAS} androgen receptor signaling pathway, positive regulation of transcription, DNA-dependent, protein ubiquitination, regulation of androgen receptor signaling pathway, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, response to estradiol stimulus, signal transduction, transcription, DNA-dependent cytoplasm, nucleus androgen receptor binding, protein binding, small conjugating protein ligase activity, transcription coactivator activity, zinc ion binding Human RNF141 ENSEMBL UniProtKB {GO:0006355=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000019} Q8WVD5 RING finger protein 141 protein 20130413 {GO:0006355=IEA, GO:0008270=IEA, GO:0003677=IEA} regulation of transcription, DNA-dependent DNA binding, zinc ion binding Human Ensembl:ENSMUSP00000134781 RNF144A UniProtKB UniProtKB {GO:0005794=PMID:10942595, GO:0016567=GO_REF:0000041, GO:0016874=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037} P50876 Probable E3 ubiquitin-protein ligase RNF144A protein 20060117 {GO:0005794=IDA, GO:0016567=IEA, GO:0016874=IEA, GO:0008270=IEA, GO:0016021=IEA} protein ubiquitination Golgi apparatus, integral to membrane ligase activity, zinc ion binding Human RNF144B UniProtKB UniProtKB {GO:0005515=PMID:20300062, GO:0005737=PMID:20300062, GO:0004842=PMID:12853982, GO:0031966=PMID:20300062, GO:0042787=PMID:12853982, GO:0016874=GO_REF:0000038, GO:0000151=PMID:12853982, GO:0006915=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q7Z419 E3 ubiquitin-protein ligase RNF144B protein 20110418 {GO:0005515=IPI, GO:0005737=IDA, GO:0004842=IDA, GO:0031966=IDA, GO:0042787=IDA, GO:0016874=IEA, GO:0000151=IC, GO:0006915=IEA, GO:0008270=IEA, GO:0016021=IEA} apoptotic process, protein ubiquitination involved in ubiquitin-dependent protein catabolic process cytoplasm, integral to membrane, mitochondrial membrane, ubiquitin ligase complex ligase activity, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q07812 RNF145 UniProtKB UniProtKB {GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q96MT1 RING finger protein 145 protein 20130413 {GO:0008270=IEA, GO:0016021=IEA} integral to membrane zinc ion binding Human UniProtKB-KW:KW-0812 RNF146 UniProtKB UniProtKB {GO:0005515=PMID:21478859, GO:0072572=PMID:21478859, GO:0004842=PMID:21478859, GO:0042787=PMID:21478859, GO:0090263=PMID:21478859, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0070936=PMID:21478859, GO:0016055=GO_REF:0000037, GO:0051865=PMID:21478859, GO:0005829=PMID:15813938} Q9NTX7 E3 ubiquitin-protein ligase RNF146 protein 20110420 {GO:0005515=IPI, GO:0072572=IDA, GO:0004842=IDA, GO:0042787=IMP, GO:0090263=IMP, GO:0005634=IEA, GO:0008270=IEA, GO:0070936=IMP, GO:0016055=IEA, GO:0051865=IDA, GO:0005829=IDA} Wnt receptor signaling pathway, positive regulation of canonical Wnt receptor signaling pathway, protein K48-linked ubiquitination, protein autoubiquitination, protein ubiquitination involved in ubiquitin-dependent protein catabolic process cytosol, nucleus poly-ADP-D-ribose binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:O15169 RNF149 UniPathway UniProtKB {GO:0016567=GO_REF:0000041, GO:0016874=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q8NC42 E3 ubiquitin-protein ligase RNF149 protein 20130413 {GO:0016567=IEA, GO:0016874=IEA, GO:0008270=IEA, GO:0016021=IEA} protein ubiquitination integral to membrane ligase activity, zinc ion binding Human UniPathway:UPA00143 RNF150 UniProtKB UniProtKB {GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q9ULK6 RING finger protein 150 protein 20130413 {GO:0008270=IEA, GO:0016021=IEA} integral to membrane zinc ion binding Human UniProtKB-KW:KW-0812 RNF151 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0004842=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0007283=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q2KHN1 RING finger protein 151 protein 20130413 {GO:0005737=IEA, GO:0004842=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0007283=IEA, GO:0030154=IEA} cell differentiation, spermatogenesis cytoplasm, nucleus ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB-SubCell:SL-0086 RNF152 UniProtKB UniProtKB {GO:0004842=PMID:21203937, GO:0006915=PMID:21203937, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0070936=PMID:21203937, GO:0005765=GO_REF:0000039, GO:0005764=PMID:21203937} Q8N8N0 E3 ubiquitin-protein ligase RNF152 protein 20110120 {GO:0004842=IDA, GO:0006915=TAS, GO:0008270=IEA, GO:0016021=IEA, GO:0070936=IDA, GO:0005765=IEA, GO:0005764=IDA} apoptotic process, protein K48-linked ubiquitination integral to membrane, lysosomal membrane, lysosome ubiquitin-protein ligase activity, zinc ion binding Human RNF157 InterPro UniProtKB {GO:0008270=GO_REF:0000002} Q96PX1 RING finger protein 157 protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR001841 RNF165 InterPro UniProtKB {GO:0008270=GO_REF:0000002} Q6ZSG1 RING finger protein 165 protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR001841 RNF166 InterPro UniProtKB {GO:0008270=GO_REF:0000002} Q96A37 RING finger protein 166 protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR001841 RNF167 UniProtKB UniProtKB {GO:0000209=PMID:16314844, GO:0005515=PMID:16314844, GO:0004842=PMID:16314844, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0045786=PMID:16314844, GO:0012505=GO_REF:0000039} Q9H6Y7 E3 ubiquitin-protein ligase RNF167 protein 20090731 {GO:0000209=IDA, GO:0005515=IPI, GO:0004842=IDA, GO:0008270=IEA, GO:0016021=IEA, GO:0045786=IMP, GO:0012505=IEA} negative regulation of cell cycle, protein polyubiquitination endomembrane system, integral to membrane protein binding, ubiquitin-protein ligase activity, zinc ion binding Human RNF168 IntAct UniProtKB {GO:0005515=PMID:19203578, GO:0043130=PMID:19203579, GO:0006511=PMID:22373579, GO:0035518=PMID:22980979, GO:0004842=PMID:22980979, GO:0016567=PMID:22373579, GO:0000151=PMID:19203579, GO:0005634=PMID:19203578, GO:0036351=PMID:22980979, GO:0045739=PMID:19203579, GO:0036352=PMID:22980979, GO:0036297=PMID:22705371, GO:0006302=PMID:22980979, GO:0042393=PMID:19203579, GO:0070534=PMID:22266820, GO:0070535=PMID:20550933, GO:0010212=PMID:19203579, GO:0070530=PMID:22742833, GO:0045900=PMID:20550933, GO:0045190=GO_REF:0000024, GO:0035861=PMID:19500350, GO:0031491=PMID:22742833, GO:0006974=PMID:22980979, GO:0003682=PMID:19500350, GO:0008270=GO_REF:0000002} Q8IYW5 E3 ubiquitin-protein ligase RNF168 protein 20130415 {GO:0005515=IPI, GO:0043130=IDA, GO:0006511=IDA, GO:0035518=IDA, GO:0004842=IDA, GO:0016567=IDA, GO:0000151=IDA, GO:0005634=IDA, GO:0036351=IDA, GO:0045739=IDA, GO:0036352=IDA, GO:0036297=TAS, GO:0006302=IDA, GO:0042393=IDA, GO:0070534=IDA, GO:0070535=IMP, GO:0010212=IDA, GO:0070530=IDA, GO:0045900=IMP, GO:0045190=ISS, GO:0035861=IDA, GO:0031491=IDA, GO:0006974=IDA, GO:0003682=IDA, GO:0008270=IEA} double-strand break repair, histone H2A K63-linked ubiquitination, histone H2A monoubiquitination, histone H2A-K13 ubiquitination, histone H2A-K15 ubiquitination, interstrand cross-link repair, isotype switching, negative regulation of translational elongation, positive regulation of DNA repair, protein K63-linked ubiquitination, protein ubiquitination, response to DNA damage stimulus, response to ionizing radiation, ubiquitin-dependent protein catabolic process nucleus, site of double-strand break, ubiquitin ligase complex K63-linked polyubiquitin binding, chromatin binding, histone binding, nucleosome binding, protein binding, ubiquitin binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:P61088 RNF169 UniProtKB UniProtKB {GO:2000780=PMID:22492721, GO:0016567=GO_REF:0000041, GO:0016874=GO_REF:0000037, GO:0035861=PMID:22492721, GO:0031491=PMID:22742833, GO:0005654=PMID:22492721, GO:0005634=PMID:22733822, GO:0008270=GO_REF:0000002, GO:0070530=PMID:22492721, GO:0006974=PMID:22492721} Q8NCN4 E3 ubiquitin-protein ligase RNF169 protein 20120430 {GO:2000780=IMP, GO:0016567=IEA, GO:0016874=IEA, GO:0035861=IDA, GO:0031491=IDA, GO:0005654=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0070530=IDA, GO:0006974=IMP} negative regulation of double-strand break repair, protein ubiquitination, response to DNA damage stimulus nucleoplasm, nucleus, site of double-strand break K63-linked polyubiquitin binding, ligase activity, nucleosome binding, zinc ion binding Human RNF17 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0007286=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0042803=GO_REF:0000019} Q9BXT8 RING finger protein 17 protein 20130413 {GO:0005737=IEA, GO:0007286=IEA, GO:0005634=IEA, GO:0007275=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0042803=IEA} multicellular organismal development, spermatid development cytoplasm, nucleus nucleic acid binding, protein homodimerization activity, zinc ion binding Human UniProtKB-SubCell:SL-0086 RNF170 UniPathway UniProtKB {GO:0016567=GO_REF:0000041, GO:0016874=GO_REF:0000037, GO:0005789=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q96K19 E3 ubiquitin-protein ligase RNF170 protein 20130413 {GO:0016567=IEA, GO:0016874=IEA, GO:0005789=IEA, GO:0008270=IEA, GO:0016021=IEA} protein ubiquitination endoplasmic reticulum membrane, integral to membrane ligase activity, zinc ion binding Human UniPathway:UPA00143 RNF180 UniProtKB UniProtKB {GO:0004842=GO_REF:0000019, GO:0032436=GO_REF:0000019, GO:0031227=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005635=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0031624=GO_REF:0000019} Q86T96 E3 ubiquitin-protein ligase RNF180 protein 20130413 {GO:0004842=IEA, GO:0032436=IEA, GO:0031227=IEA, GO:0008270=IEA, GO:0005635=IEA, GO:0016021=IEA, GO:0031624=IEA} positive regulation of proteasomal ubiquitin-dependent protein catabolic process integral to membrane, intrinsic to endoplasmic reticulum membrane, nuclear envelope ubiquitin conjugating enzyme binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB-SubCell:SL-0178 RNF181 UniPathway UniProtKB {GO:0016567=GO_REF:0000041, GO:0016874=GO_REF:0000037, GO:0008270=GO_REF:0000002} Q9P0P0 E3 ubiquitin-protein ligase RNF181 protein 20130413 {GO:0016567=IEA, GO:0016874=IEA, GO:0008270=IEA} protein ubiquitination ligase activity, zinc ion binding Human UniPathway:UPA00143 RNF182 HPA UniProtKB {GO:0005515=PMID:18298843, GO:0004842=PMID:18298843, GO:0005737=PMID:18298843, GO:0016567=PMID:18298843, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q8N6D2 E3 ubiquitin-protein ligase RNF182 protein 20081203 {GO:0005515=IPI, GO:0004842=IDA, GO:0005737=IDA, GO:0016567=IDA, GO:0008270=IEA, GO:0016021=IEA, GO:0043231=IDA} protein ubiquitination cytoplasm, integral to membrane, intracellular membrane-bounded organelle protein binding, ubiquitin-protein ligase activity, zinc ion binding Human RNF183 UniProtKB UniProtKB {GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q96D59 RING finger protein 183 protein 20130413 {GO:0008270=IEA, GO:0016021=IEA} integral to membrane zinc ion binding Human UniProtKB-KW:KW-0812 RNF185 UniPathway UniProtKB {GO:0016567=GO_REF:0000041, GO:0016874=GO_REF:0000037, GO:0006914=GO_REF:0000037, GO:0005741=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q96GF1 E3 ubiquitin-protein ligase RNF185 protein 20130413 {GO:0016567=IEA, GO:0016874=IEA, GO:0006914=IEA, GO:0005741=IEA, GO:0008270=IEA, GO:0016021=IEA} autophagy, protein ubiquitination integral to membrane, mitochondrial outer membrane ligase activity, zinc ion binding Human UniPathway:UPA00143 RNF186 UniProtKB UniProtKB {GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q9NXI6 RING finger protein 186 protein 20130413 {GO:0008270=IEA, GO:0016021=IEA} integral to membrane zinc ion binding Human UniProtKB-KW:KW-0812 RNF187 UniProtKB UniProtKB {GO:0005515=PMID:20852630, GO:0005737=PMID:20852630, GO:0008284=GO_REF:0000024, GO:0004842=PMID:20852630, GO:0005634=PMID:20852630, GO:0043161=PMID:20852630, GO:0008270=GO_REF:0000002, GO:0070936=PMID:20852630, GO:0045893=PMID:20852630, GO:0051865=PMID:20852630} Q5TA31 E3 ubiquitin-protein ligase RNF187 protein 20110427 {GO:0005515=IPI, GO:0005737=IDA, GO:0008284=ISS, GO:0004842=IDA, GO:0005634=IDA, GO:0043161=IMP, GO:0008270=IEA, GO:0070936=IMP, GO:0045893=IMP, GO:0051865=IDA} positive regulation of cell proliferation, positive regulation of transcription, DNA-dependent, proteasomal ubiquitin-dependent protein catabolic process, protein K48-linked ubiquitination, protein autoubiquitination cytoplasm, nucleus protein binding, ubiquitin-protein ligase activity, zinc ion binding Human RNF19A UniPathway UniProtKB {GO:0005813=PMID:11237715, GO:0005737=GO_REF:0000037, GO:0016567=GO_REF:0000041, GO:0016874=GO_REF:0000037, GO:0000226=PMID:11237715, GO:0008270=GO_REF:0000029, GO:0016021=GO_REF:0000037, GO:0006464=GO_REF:0000029, GO:0008134=PMID:10976766} Q9NV58 E3 ubiquitin-protein ligase RNF19A protein 20130413 {GO:0005813=TAS, GO:0005737=IEA, GO:0016567=IEA, GO:0016874=IEA, GO:0000226=TAS, GO:0008270=NAS, GO:0016021=IEA, GO:0006464=NAS, GO:0008134=TAS} cellular protein modification process, microtubule cytoskeleton organization, protein ubiquitination centrosome, cytoplasm, integral to membrane ligase activity, transcription factor binding, zinc ion binding Human UniPathway:UPA00143 RNF19B IntAct UniProtKB {GO:0005515=PMID:16709802, GO:0016567=GO_REF:0000041, GO:0016874=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q6ZMZ0 E3 ubiquitin-protein ligase RNF19B protein 20130415 {GO:0005515=IPI, GO:0016567=IEA, GO:0016874=IEA, GO:0008270=IEA, GO:0016021=IEA} protein ubiquitination integral to membrane ligase activity, protein binding, zinc ion binding Human UniProtKB:P68036 RNF2 HPA UniProtKB {GO:0031519=PMID:16943429, GO:0035102=PMID:19636380, GO:0005515=PMID:22493164, GO:0035518=PMID:16943429, GO:0004842=PMID:16714294, GO:0016874=GO_REF:0000038, GO:0005730=GO_REF:0000052, GO:0000151=PMID:16714294, GO:0005634=GO_REF:0000052, GO:0000122=GO_REF:0000019, GO:0001739=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0001702=GO_REF:0000019, GO:0016604=GO_REF:0000019, GO:0009948=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0071339=PMID:15960975, GO:0008270=PMID:16714294, GO:0071535=PMID:16714294, GO:0000278=GO_REF:0000019} Q99496 E3 ubiquitin-protein ligase RING2 protein 20101115 {GO:0031519=IDA, GO:0035102=IDA, GO:0005515=IPI, GO:0035518=IDA, GO:0004842=IDA, GO:0016874=IEA, GO:0005730=IDA, GO:0000151=IDA, GO:0005634=IDA, GO:0000122=IEA, GO:0001739=IEA, GO:0006351=IEA, GO:0001702=IEA, GO:0016604=IEA, GO:0009948=IEA, GO:0003682=IEA, GO:0071339=IDA, GO:0008270=IDA, GO:0071535=IPI, GO:0000278=IEA} anterior/posterior axis specification, gastrulation with mouth forming second, histone H2A monoubiquitination, mitotic cell cycle, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent MLL1 complex, PRC1 complex, PcG protein complex, nuclear body, nucleolus, nucleus, sex chromatin, ubiquitin ligase complex RING-like zinc finger domain binding, chromatin binding, ligase activity, protein binding, ubiquitin-protein ligase activity, zinc ion binding NOT Human RNF20 IntAct UniProtKB {GO:0000209=PMID:19037095, GO:0005515=PMID:19410543, GO:0006511=PMID:19037095, GO:0006355=PMID:18832071, GO:0030336=PMID:18832071, GO:0004842=PMID:16307923, GO:0033523=PMID:16307923, GO:0033503=PMID:19410543, GO:0016574=GO_REF:0000019, GO:0003713=PMID:16337599, GO:0005730=PMID:19037095, GO:0000151=PMID:16307923, GO:0005634=PMID:16307923, GO:0042393=PMID:16337599, GO:0002039=PMID:16337599, GO:0003682=GO_REF:0000019, GO:0031062=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0045893=PMID:16713563, GO:0010390=PMID:16307923, GO:0031625=PMID:16307923} Q5VTR2 E3 ubiquitin-protein ligase BRE1A protein 20130415 {GO:0000209=IDA, GO:0005515=IPI, GO:0006511=IMP, GO:0006355=IMP, GO:0030336=IDA, GO:0004842=IDA, GO:0033523=IDA, GO:0033503=IDA, GO:0016574=IEA, GO:0003713=IDA, GO:0005730=IDA, GO:0000151=IDA, GO:0005634=IDA, GO:0042393=IDA, GO:0002039=IDA, GO:0003682=IEA, GO:0031062=IEA, GO:0008270=IEA, GO:0045893=IMP, GO:0010390=IDA, GO:0031625=IPI} histone H2B ubiquitination, histone monoubiquitination, histone ubiquitination, negative regulation of cell migration, positive regulation of histone methylation, positive regulation of transcription, DNA-dependent, protein polyubiquitination, regulation of transcription, DNA-dependent, ubiquitin-dependent protein catabolic process HULC complex, nucleolus, nucleus, ubiquitin ligase complex chromatin binding, histone binding, p53 binding, protein binding, transcription coactivator activity, ubiquitin protein ligase binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:O75150 RNF208 InterPro UniProtKB {GO:0008270=GO_REF:0000002} Q9H0X6 RING finger protein 208 protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR001841 RNF212 UniProtKB UniProtKB {GO:0000795=GO_REF:0000024, GO:0016925=GO_REF:0000041, GO:0016874=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0006311=GO_REF:0000024, GO:0007131=GO_REF:0000024} Q495C1 Probable E3 SUMO-protein ligase RNF212 protein 20130222 {GO:0000795=ISS, GO:0016925=IEA, GO:0016874=IEA, GO:0008270=IEA, GO:0006311=ISS, GO:0007131=ISS} meiotic gene conversion, protein sumoylation, reciprocal meiotic recombination synaptonemal complex ligase activity, zinc ion binding colocalizes_with Human UniProtKB:F6TQD1 RNF213 UniProtKB UniProtKB {GO:0005737=PMID:21799892, GO:0004842=PMID:21799892, GO:0017111=GO_REF:0000002, GO:0016567=PMID:21799892, GO:0006200=PMID:21799892, GO:0000166=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0016887=PMID:21799892, GO:0005524=GO_REF:0000038, GO:0051865=PMID:21799892} Q63HN8 E3 ubiquitin-protein ligase RNF213 protein 20120117 {GO:0005737=IDA, GO:0004842=IDA, GO:0017111=IEA, GO:0016567=IDA, GO:0006200=IDA, GO:0000166=IEA, GO:0008270=IEA, GO:0016887=IDA, GO:0005524=IEA, GO:0051865=IDA} ATP catabolic process, protein autoubiquitination, protein ubiquitination cytoplasm ATP binding, ATPase activity, nucleoside-triphosphatase activity, nucleotide binding, ubiquitin-protein ligase activity, zinc ion binding Human RNF214 InterPro UniProtKB {GO:0008270=GO_REF:0000002} Q8ND24 RING finger protein 214 protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR001841 RNF216 HPA UniProtKB {GO:0005515=PMID:19893624, GO:0032648=PMID:19893624, GO:0005737=GO_REF:0000052, GO:0019048=GO_REF:0000037, GO:0016874=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0043161=PMID:19893624, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0070936=PMID:19893624, GO:0050691=PMID:19893624} Q9NWF9 E3 ubiquitin-protein ligase RNF216 protein 20100326 {GO:0005515=IPI, GO:0032648=IDA, GO:0005737=IDA, GO:0019048=IEA, GO:0016874=IEA, GO:0005730=IDA, GO:0006915=IEA, GO:0043161=IDA, GO:0008270=IEA, GO:0005634=IDA, GO:0070936=IDA, GO:0050691=IDA} apoptotic process, proteasomal ubiquitin-dependent protein catabolic process, protein K48-linked ubiquitination, regulation of defense response to virus by host, regulation of interferon-beta production, virus-host interaction cytoplasm, nucleolus, nucleus ligase activity, protein binding, zinc ion binding Human RNF217 UniProtKB UniProtKB {GO:0004842=GO_REF:0000024, GO:0042787=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q8TC41 Probable E3 ubiquitin-protein ligase RNF217 protein 20050216 {GO:0004842=ISS, GO:0042787=ISS, GO:0008270=IEA, GO:0016021=IEA} protein ubiquitination involved in ubiquitin-dependent protein catabolic process integral to membrane ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q7Z419 RNF219 InterPro UniProtKB {GO:0008270=GO_REF:0000002} Q5W0B1 RING finger protein 219 protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR001841 RNF220 UniProtKB UniProtKB {GO:0004842=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0016567=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0051865=GO_REF:0000024} Q5VTB9 E3 ubiquitin-protein ligase RNF220 protein 20100614 {GO:0004842=ISS, GO:0005737=ISS, GO:0016567=ISS, GO:0008270=IEA, GO:0051865=ISS} protein autoubiquitination, protein ubiquitination cytoplasm ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q6PDX6 RNF24 UniProtKB UniProtKB {GO:0000139=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q9Y225 RING finger protein 24 protein 20130413 {GO:0000139=IEA, GO:0008270=IEA, GO:0016021=IEA} Golgi membrane, integral to membrane zinc ion binding Human UniProtKB-SubCell:SL-0134 RNF25 UniProtKB UniProtKB {GO:0004842=GO_REF:0000024, GO:0016567=GO_REF:0000024, GO:0051092=PMID:12748188, GO:0051059=PMID:12748188, GO:0005634=PMID:12748188, GO:0008270=GO_REF:0000002, GO:0005829=PMID:12748188} Q96BH1 E3 ubiquitin-protein ligase RNF25 protein 20100609 {GO:0004842=ISS, GO:0016567=ISS, GO:0051092=IDA, GO:0051059=IPI, GO:0005634=IDA, GO:0008270=IEA, GO:0005829=IDA} positive regulation of NF-kappaB transcription factor activity, protein ubiquitination cytosol, nucleus NF-kappaB binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q9QZR0 RNF26 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0008270=PMID:11352657, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} Q9BY78 RING finger protein 26 protein 20061026 {GO:0008150=ND, GO:0008270=NAS, GO:0005575=ND, GO:0016021=IEA} biological_process cellular_component, integral to membrane zinc ion binding Human RNF31 BHF-UCL UniProtKB {GO:0005515=PMID:21988832, GO:0000209=PMID:17006537, GO:0035631=GO_REF:0000024, GO:0043130=PMID:21455181, GO:0050852=PMID:20005846, GO:0004842=PMID:17006537, GO:0023035=GO_REF:0000024, GO:0071797=PMID:17006537, GO:0097039=PMID:21455181, GO:0005737=GO_REF:0000039, GO:0051092=PMID:19136968, GO:0009898=PMID:20614026, GO:0008270=GO_REF:0000002, GO:0043123=PMID:19136968} Q96EP0 E3 ubiquitin-protein ligase RNF31 protein 20110110 {GO:0005515=IPI, GO:0000209=IDA, GO:0035631=ISS, GO:0043130=IDA, GO:0050852=IDA, GO:0004842=IDA, GO:0023035=ISS, GO:0071797=IDA, GO:0097039=IDA, GO:0005737=IEA, GO:0051092=IDA, GO:0009898=ISS, GO:0008270=IEA, GO:0043123=IDA} CD40 signaling pathway, T cell receptor signaling pathway, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB transcription factor activity, protein linear polyubiquitination, protein polyubiquitination CD40 receptor complex, LUBAC complex, cytoplasm, internal side of plasma membrane protein binding, ubiquitin binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q924T7 RNF32 IntAct UniProtKB {GO:0005515=PMID:21163940, GO:0016235=PMID:11890671, GO:0008270=GO_REF:0000002, GO:0005768=GO_REF:0000054} Q9H0A6 RING finger protein 32 protein 20130415 {GO:0005515=IPI, GO:0016235=IDA, GO:0008270=IEA, GO:0005768=IDA} aggresome, endosome protein binding, zinc ion binding Human UniProtKB:Q9NXK8 RNF34 UniProtKB UniProtKB {GO:0004842=GO_REF:0000019, GO:0016607=GO_REF:0000039, GO:0016020=GO_REF:0000037, GO:0006915=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0012505=GO_REF:0000039} Q969K3 E3 ubiquitin-protein ligase RNF34 protein 20130413 {GO:0004842=IEA, GO:0016607=IEA, GO:0016020=IEA, GO:0006915=IEA, GO:0008270=IEA, GO:0012505=IEA} apoptotic process endomembrane system, membrane, nuclear speck ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB-SubCell:SL-0186 RNF38 InterPro UniProtKB {GO:0008270=GO_REF:0000002} Q9H0F5 RING finger protein 38 protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR001841 RNF39 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000039, GO:0008270=GO_REF:0000029, GO:0005575=GO_REF:0000015} Q9H2S5 RING finger protein 39 protein 20061113 {GO:0008150=ND, GO:0005737=IEA, GO:0008270=NAS, GO:0005575=ND} biological_process cellular_component, cytoplasm zinc ion binding Human RNF4 HPA UniProtKB {GO:0005515=PMID:20212317, GO:0046685=PMID:20943951, GO:0004842=GO_REF:0000024, GO:0003700=PMID:9710597, GO:0033142=GO_REF:0000019, GO:0005634=PMID:12885770, GO:0050681=PMID:15572661, GO:0090169=PMID:20212317, GO:0070534=GO_REF:0000024, GO:0005737=PMID:12885770, GO:0045944=PMID:12885770, GO:0015630=GO_REF:0000052, GO:0085020=GO_REF:0000024, GO:0032184=GO_REF:0000024, GO:0030331=GO_REF:0000019, GO:0003713=PMID:15572661, GO:0031491=GO_REF:0000024, GO:0090234=PMID:20212317, GO:0003677=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0051865=GO_REF:0000024, GO:0070979=GO_REF:0000024, GO:0016605=PMID:20943951, GO:0043161=PMID:20212317, GO:0008270=GO_REF:0000002, GO:0045893=GO_REF:0000024, GO:0070936=GO_REF:0000024, GO:0030521=PMID:15572661, GO:0008134=GO_REF:0000019} P78317 E3 ubiquitin-protein ligase RNF4 protein 20120912 {GO:0005515=IPI, GO:0046685=IDA, GO:0004842=ISS, GO:0003700=TAS, GO:0033142=IEA, GO:0005634=IDA, GO:0050681=NAS, GO:0090169=IMP, GO:0070534=ISS, GO:0005737=IDA, GO:0045944=IDA, GO:0015630=IDA, GO:0085020=ISS, GO:0032184=ISS, GO:0030331=IEA, GO:0003713=NAS, GO:0031491=ISS, GO:0090234=IMP, GO:0003677=ISS, GO:0006351=IEA, GO:0051865=ISS, GO:0070979=ISS, GO:0016605=IDA, GO:0043161=IMP, GO:0008270=IEA, GO:0045893=ISS, GO:0070936=ISS, GO:0030521=NAS, GO:0008134=IEA} androgen receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, proteasomal ubiquitin-dependent protein catabolic process, protein K11-linked ubiquitination, protein K48-linked ubiquitination, protein K6-linked ubiquitination, protein K63-linked ubiquitination, protein autoubiquitination, regulation of kinetochore assembly, regulation of spindle assembly, response to arsenic-containing substance, transcription, DNA-dependent PML body, cytoplasm, microtubule cytoskeleton, nucleus DNA binding, SUMO polymer binding, androgen receptor binding, estrogen receptor binding, nucleosome binding, progesterone receptor binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, transcription factor binding, ubiquitin-protein ligase activity, zinc ion binding Human RNF40 HPA UniProtKB {GO:0005515=PMID:19410543, GO:0006511=GO_REF:0000024, GO:0043005=GO_REF:0000024, GO:0004842=PMID:16307923, GO:0033523=PMID:16307923, GO:0005886=GO_REF:0000052, GO:0033503=PMID:19410543, GO:0005730=GO_REF:0000052, GO:0000151=PMID:16307923, GO:0005634=GO_REF:0000052, GO:0032403=GO_REF:0000019, GO:0042803=PMID:10944455, GO:0043234=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0017075=GO_REF:0000019, GO:0010390=PMID:16307923, GO:0031625=PMID:16307923} O75150 E3 ubiquitin-protein ligase BRE1B protein 20111111 {GO:0005515=IPI, GO:0006511=ISS, GO:0043005=ISS, GO:0004842=IDA, GO:0033523=IDA, GO:0005886=IDA, GO:0033503=IDA, GO:0005730=IDA, GO:0000151=IDA, GO:0005634=IDA, GO:0032403=IEA, GO:0042803=IPI, GO:0043234=IEA, GO:0005737=IDA, GO:0008270=IEA, GO:0017075=IEA, GO:0010390=IDA, GO:0031625=IPI} histone H2B ubiquitination, histone monoubiquitination, ubiquitin-dependent protein catabolic process HULC complex, cytoplasm, neuron projection, nucleolus, nucleus, plasma membrane, protein complex, ubiquitin ligase complex protein binding, protein complex binding, protein homodimerization activity, syntaxin-1 binding, ubiquitin protein ligase binding, ubiquitin-protein ligase activity, zinc ion binding Human RNF41 Reactome UniProtKB {GO:0000209=PMID:14765125, GO:0005515=PMID:11867753, GO:0030336=PMID:17145873, GO:0004842=Reactome:REACT_115599, GO:0005135=GO_REF:0000019, GO:0008285=PMID:17145873, GO:0006915=GO_REF:0000037, GO:0006917=PMID:14765125, GO:0051896=PMID:17145873, GO:0005829=Reactome:REACT_116151, GO:0045619=GO_REF:0000019, GO:0043408=PMID:17145873, GO:0031386=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0045637=GO_REF:0000019, GO:2000377=PMID:18541373, GO:0005128=GO_REF:0000019} Q9H4P4 E3 ubiquitin-protein ligase NRDP1 protein 20110805 {GO:0000209=IDA, GO:0005515=IPI, GO:0030336=IMP, GO:0004842=TAS, GO:0005135=IEA, GO:0008285=IDA, GO:0006915=IEA, GO:0006917=IDA, GO:0051896=IDA, GO:0005829=TAS, GO:0045619=IEA, GO:0043408=IDA, GO:0031386=IEA, GO:0008270=IEA, GO:0045637=IEA, GO:2000377=IMP, GO:0005128=IEA} apoptotic process, induction of apoptosis, negative regulation of cell migration, negative regulation of cell proliferation, protein polyubiquitination, regulation of MAPK cascade, regulation of lymphocyte differentiation, regulation of myeloid cell differentiation, regulation of protein kinase B signaling cascade, regulation of reactive oxygen species metabolic process cytosol erythropoietin receptor binding, interleukin-3 receptor binding, protein binding, protein tag, ubiquitin-protein ligase activity, zinc ion binding Human RNF43 IntAct UniProtKB {GO:0005515=PMID:19690564, GO:0004842=PMID:22575959, GO:0016567=PMID:22575959, GO:0030178=PMID:22575959, GO:0072089=GO_REF:0000024, GO:0005635=GO_REF:0000039, GO:0005109=PMID:22895187, GO:0038018=PMID:22895187, GO:0042787=PMID:22895187, GO:0005887=PMID:22575959, GO:0005789=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0016055=GO_REF:0000037} Q68DV7 E3 ubiquitin-protein ligase RNF43 protein 20130415 {GO:0005515=IPI, GO:0004842=IDA, GO:0016567=IDA, GO:0030178=IMP, GO:0072089=ISS, GO:0005635=IEA, GO:0005109=IPI, GO:0038018=IDA, GO:0042787=IDA, GO:0005887=IDA, GO:0005789=IEA, GO:0008270=IEA, GO:0016055=IEA} Wnt receptor catabolic process, Wnt receptor signaling pathway, negative regulation of Wnt receptor signaling pathway, protein ubiquitination, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, stem cell proliferation endoplasmic reticulum membrane, integral to plasma membrane, nuclear envelope frizzled binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:P62837 RNF44 InterPro UniProtKB {GO:0008270=GO_REF:0000002} Q7L0R7 RING finger protein 44 protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR001841 RNF5 IntAct UniProtKB {GO:0005515=PMID:19549727, GO:0004842=PMID:19269966, GO:0070534=PMID:19269966, GO:0031966=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0044257=PMID:19285439, GO:0070936=PMID:19285439, GO:0071712=PMID:19269966} Q99942 E3 ubiquitin-protein ligase RNF5 protein 20130415 {GO:0005515=IPI, GO:0004842=IDA, GO:0070534=IDA, GO:0031966=IEA, GO:0005789=IEA, GO:0008270=IEA, GO:0016021=IEA, GO:0044257=IMP, GO:0070936=IDA, GO:0071712=IMP} ER-associated misfolded protein catabolic process, cellular protein catabolic process, protein K48-linked ubiquitination, protein K63-linked ubiquitination endoplasmic reticulum membrane, integral to membrane, mitochondrial membrane protein binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:P62837 RNF6 UniProtKB UniProtKB {GO:0006511=GO_REF:0000024, GO:0030424=GO_REF:0000024, GO:0085020=PMID:19345326, GO:0006355=PMID:19345326, GO:0004842=PMID:19345326, GO:0060765=PMID:19345326, GO:0005634=PMID:19345326, GO:0050681=PMID:19345326, GO:0044314=PMID:19345326, GO:0003677=GO_REF:0000019, GO:0005737=PMID:19345326, GO:0030517=GO_REF:0000024, GO:0016605=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0045893=PMID:19345326, GO:0070936=GO_REF:0000024} Q9Y252 E3 ubiquitin-protein ligase RNF6 protein 20100604 {GO:0006511=ISS, GO:0030424=ISS, GO:0085020=IDA, GO:0006355=IMP, GO:0004842=IMP, GO:0060765=IMP, GO:0005634=IDA, GO:0050681=IPI, GO:0044314=IDA, GO:0003677=IEA, GO:0005737=IDA, GO:0030517=ISS, GO:0016605=IEA, GO:0008270=IEA, GO:0045893=IMP, GO:0070936=ISS} negative regulation of axon extension, positive regulation of transcription, DNA-dependent, protein K27-linked ubiquitination, protein K48-linked ubiquitination, protein K6-linked ubiquitination, regulation of androgen receptor signaling pathway, regulation of transcription, DNA-dependent, ubiquitin-dependent protein catabolic process PML body, axon, cytoplasm, nucleus DNA binding, androgen receptor binding, ubiquitin-protein ligase activity, zinc ion binding Human RNF7 HPA UniProtKB {GO:0005515=PMID:22190034, GO:0043066=PMID:10082581, GO:0016567=GO_REF:0000041, GO:0045116=PMID:19250909, GO:0005507=PMID:10082581, GO:0008631=PMID:10082581, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0019788=PMID:19250909, GO:0051775=PMID:10082581, GO:0008270=GO_REF:0000002, GO:0031466=PMID:22405651} Q9UBF6 RING-box protein 2 protein 20110516 {GO:0005515=IPI, GO:0043066=TAS, GO:0016567=IEA, GO:0045116=IDA, GO:0005507=TAS, GO:0008631=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0005737=IDA, GO:0019788=IDA, GO:0051775=TAS, GO:0008270=IEA, GO:0031466=IDA} intrinsic apoptotic signaling pathway in response to oxidative stress, negative regulation of apoptotic process, protein neddylation, protein ubiquitination, response to redox state Cul5-RING ubiquitin ligase complex, cytoplasm, nucleolus, nucleus NEDD8 ligase activity, copper ion binding, protein binding, zinc ion binding Human RNF8 UniProtKB UniProtKB {GO:0005515=PMID:22266820, GO:0006511=PMID:22266820, GO:0004842=PMID:21911360, GO:0016567=GO_REF:0000002, GO:0033523=GO_REF:0000024, GO:0033522=PMID:18001825, GO:0007286=GO_REF:0000024, GO:0000151=PMID:18001825, GO:0005634=PMID:18001825, GO:0045739=PMID:18001824, GO:0006303=GO_REF:0000024, GO:0042803=PMID:22980979, GO:0036297=PMID:22705371, GO:0006302=PMID:22980979, GO:0042393=PMID:18001825, GO:0070534=PMID:21911360, GO:0070535=PMID:22980979, GO:0010212=PMID:18001825, GO:0031625=PMID:22266820, GO:0045900=PMID:20550933, GO:0000781=GO_REF:0000024, GO:0043486=GO_REF:0000024, GO:0016881=GO_REF:0000002, GO:0045190=GO_REF:0000024, GO:0035861=PMID:22266820, GO:0030496=GO_REF:0000039, GO:0006974=PMID:22266820, GO:0051865=PMID:22266820, GO:0007067=GO_REF:0000037, GO:0003682=PMID:18001825, GO:0008270=PMID:22980979, GO:0070936=PMID:21911360, GO:0051301=GO_REF:0000037} O76064 E3 ubiquitin-protein ligase RNF8 protein 20120827 {GO:0005515=IPI, GO:0006511=IDA, GO:0004842=IDA, GO:0016567=IEA, GO:0033523=ISS, GO:0033522=IDA, GO:0007286=ISS, GO:0000151=IDA, GO:0005634=IDA, GO:0045739=IDA, GO:0006303=ISS, GO:0042803=IDA, GO:0036297=TAS, GO:0006302=IDA, GO:0042393=IDA, GO:0070534=IDA, GO:0070535=IDA, GO:0010212=IDA, GO:0031625=IPI, GO:0045900=IMP, GO:0000781=ISS, GO:0043486=ISS, GO:0016881=IEA, GO:0045190=ISS, GO:0035861=IDA, GO:0030496=IEA, GO:0006974=IDA, GO:0051865=IDA, GO:0007067=IEA, GO:0003682=IDA, GO:0008270=IDA, GO:0070936=IDA, GO:0051301=IEA} cell division, double-strand break repair, double-strand break repair via nonhomologous end joining, histone H2A K63-linked ubiquitination, histone H2A ubiquitination, histone H2B ubiquitination, histone exchange, interstrand cross-link repair, isotype switching, mitosis, negative regulation of translational elongation, positive regulation of DNA repair, protein K48-linked ubiquitination, protein K63-linked ubiquitination, protein autoubiquitination, protein ubiquitination, response to DNA damage stimulus, response to ionizing radiation, spermatid development, ubiquitin-dependent protein catabolic process chromosome, telomeric region, midbody, nucleus, site of double-strand break, ubiquitin ligase complex acid-amino acid ligase activity, chromatin binding, histone binding, protein binding, protein homodimerization activity, ubiquitin protein ligase binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:P13010 RNFT1 UniProtKB UniProtKB {GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q5M7Z0 RING finger and transmembrane domain-containing protein 1 protein 20130413 {GO:0008270=IEA, GO:0016021=IEA} integral to membrane zinc ion binding Human UniProtKB-KW:KW-0812 RNFT2 UniProtKB UniProtKB {GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q96EX2 RING finger and transmembrane domain-containing protein 2 protein 20130413 {GO:0008270=IEA, GO:0016021=IEA} integral to membrane zinc ion binding Human UniProtKB-KW:KW-0812 RNGTT InterPro UniProtKB {GO:0022415=Reactome:REACT_6361, GO:0006396=PMID:9473487, GO:0010467=Reactome:REACT_71, GO:0006366=Reactome:REACT_1366, GO:0006370=GO_REF:0000002, GO:0005634=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0004651=GO_REF:0000002, GO:0004484=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0016032=Reactome:REACT_6256, GO:0005654=Reactome:REACT_2233, GO:0008138=GO_REF:0000002, GO:0004725=GO_REF:0000002} Q5TCW7 mRNA-capping enzyme protein 20130413 {GO:0022415=TAS, GO:0006396=TAS, GO:0010467=TAS, GO:0006366=TAS, GO:0006370=IEA, GO:0005634=IEA, GO:0005525=IEA, GO:0004651=IEA, GO:0004484=IEA, GO:0019048=IEA, GO:0016032=TAS, GO:0005654=TAS, GO:0008138=IEA, GO:0004725=IEA} 7-methylguanosine mRNA capping, RNA processing, gene expression, transcription from RNA polymerase II promoter, viral reproduction, viral reproductive process, virus-host interaction nucleoplasm, nucleus GTP binding, mRNA guanylyltransferase activity, polynucleotide 5'-phosphatase activity, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human InterPro:IPR000340 RNH1 HPA UniProtKB {GO:0005515=PMID:17350650, GO:0005737=GO_REF:0000052, GO:0032311=PMID:3470787, GO:0008428=PMID:3470787, GO:0045765=PMID:3470787, GO:0006402=PMID:2081593} P13489 Ribonuclease inhibitor protein 20111111 {GO:0005515=IPI, GO:0005737=IDA, GO:0032311=IPI, GO:0008428=IDA, GO:0045765=IDA, GO:0006402=NAS} mRNA catabolic process, regulation of angiogenesis angiogenin-PRI complex, cytoplasm protein binding, ribonuclease inhibitor activity Human RNLS UniProtKB UniProtKB {GO:0016491=GO_REF:0000037, GO:0005576=GO_REF:0000039} Q5VYX0 Renalase protein 20130413 {GO:0016491=IEA, GO:0005576=IEA} extracellular region oxidoreductase activity Human UniProtKB-SubCell:SL-0243 RNMT GOC UniProtKB {GO:0005515=PMID:22099306, GO:0010467=Reactome:REACT_71, GO:0022415=Reactome:REACT_6361, GO:0006366=Reactome:REACT_1366, GO:0003723=PMID:9790902, GO:0005730=GO_REF:0000052, GO:0006370=Reactome:REACT_1470, GO:0005634=GO_REF:0000052, GO:0036265=Reactome:REACT_404, GO:0004482=Reactome:REACT_404, GO:0016032=Reactome:REACT_6256, GO:0005654=Reactome:REACT_2186, GO:0005845=PMID:22099306} O43148 mRNA cap guanine-N7 methyltransferase protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0022415=TAS, GO:0006366=TAS, GO:0003723=IMP, GO:0005730=IDA, GO:0006370=TAS, GO:0005634=IDA, GO:0036265=TAS, GO:0004482=TAS, GO:0016032=TAS, GO:0005654=TAS, GO:0005845=IDA} 7-methylguanosine mRNA capping, RNA (guanine-N7)-methylation, gene expression, transcription from RNA polymerase II promoter, viral reproduction, viral reproductive process mRNA cap binding complex, nucleolus, nucleoplasm, nucleus RNA binding, mRNA (guanine-N7-)-methyltransferase activity, protein binding Human RNMTL1 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0006396=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0008173=GO_REF:0000002} Q9HC36 RNA methyltransferase-like protein 1 protein 20130413 {GO:0005739=IEA, GO:0006396=IEA, GO:0003723=IEA, GO:0008173=IEA} RNA processing mitochondrion RNA binding, RNA methyltransferase activity Human Ensembl:ENSMUSP00000042882 RNPC3 MGI UniProtKB {GO:0008380=PMID:15146077, GO:0006397=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005634=PMID:18559850, GO:0003676=GO_REF:0000002, GO:0005689=PMID:15146077} Q96LT9 RNA-binding protein 40 protein 20081010 {GO:0008380=IC, GO:0006397=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0005634=IDA, GO:0003676=IEA, GO:0005689=IDA} RNA splicing, mRNA processing U12-type spliceosomal complex, nucleus RNA binding, nucleic acid binding, nucleotide binding Human RNPEP UniProtKB UniProtKB {GO:0019370=GO_REF:0000002, GO:0005886=PMID:9405297, GO:0004177=PMID:9405297, GO:0008235=PMID:12119107, GO:0006508=PMID:12119107, GO:0005576=PMID:9405297, GO:0008270=PMID:12119107, GO:0005615=GO_REF:0000002, GO:0008237=GO_REF:0000002, GO:0004301=PMID:12119107} Q9H4A4 Aminopeptidase B protein 20091215 {GO:0019370=IEA, GO:0005886=ISS, GO:0004177=ISS, GO:0008235=NAS, GO:0006508=IC, GO:0005576=ISS, GO:0008270=NAS, GO:0005615=IEA, GO:0008237=IEA, GO:0004301=NAS} leukotriene biosynthetic process, proteolysis extracellular region, extracellular space, plasma membrane aminopeptidase activity, epoxide hydrolase activity, metalloexopeptidase activity, metallopeptidase activity, zinc ion binding Human UniProtKB:O09175 RNPEPL1 UniProtKB UniProtKB {GO:0019370=GO_REF:0000002, GO:0004177=GO_REF:0000037, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0008237=GO_REF:0000037} Q9HAU8 Arginyl aminopeptidase-like 1 protein 20130413 {GO:0019370=IEA, GO:0004177=IEA, GO:0006508=IEA, GO:0008270=IEA, GO:0008237=IEA} leukotriene biosynthetic process, proteolysis aminopeptidase activity, metallopeptidase activity, zinc ion binding Human UniProtKB-KW:KW-0482 RNPS1 IntAct UniProtKB {GO:0005515=PMID:11477570, GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0016070=Reactome:REACT_21257, GO:0006366=Reactome:REACT_1366, GO:0016071=Reactome:REACT_20605, GO:0003723=PMID:9580558, GO:0031124=Reactome:REACT_1849, GO:0005634=PMID:11546874, GO:0003676=GO_REF:0000002, GO:0006351=PMID:9580558, GO:0005829=Reactome:REACT_75910, GO:0005737=PMID:11546874, GO:0006406=Reactome:REACT_1597, GO:0016607=GO_REF:0000039, GO:0000184=Reactome:REACT_75886, GO:0000166=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0005654=Reactome:REACT_2104, GO:0003730=PMID:11546874, GO:0035145=PMID:11546874} Q15287 RNA-binding protein with serine-rich domain 1 protein 20130415 {GO:0005515=IPI, GO:0008380=TAS, GO:0010467=TAS, GO:0006369=TAS, GO:0016070=TAS, GO:0006366=TAS, GO:0016071=TAS, GO:0003723=TAS, GO:0031124=TAS, GO:0005634=IDA, GO:0003676=IEA, GO:0006351=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0006406=TAS, GO:0016607=IEA, GO:0000184=TAS, GO:0000166=IEA, GO:0000398=TAS, GO:0005654=TAS, GO:0003730=IDA, GO:0035145=TAS} RNA metabolic process, RNA splicing, gene expression, mRNA 3'-end processing, mRNA export from nucleus, mRNA metabolic process, mRNA splicing, via spliceosome, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, cytosol, exon-exon junction complex, nuclear speck, nucleoplasm, nucleus RNA binding, mRNA 3'-UTR binding, nucleic acid binding, nucleotide binding, protein binding Human UniProtKB:Q15020 ROBO1 BHF-UCL UniProtKB {GO:0005515=PMID:15207848, GO:0005886=Reactome:REACT_19396, GO:0046982=GO_REF:0000019, GO:0009986=PMID:12504588, GO:0006919=PMID:18566128, GO:0002042=PMID:19351956, GO:0060763=GO_REF:0000019, GO:0035385=PMID:18829537, GO:0021836=PMID:15207848, GO:0007399=PMID:9608531, GO:0042802=PMID:12504588, GO:0050925=PMID:11748139, GO:0005887=PMID:9608531, GO:0070100=PMID:18829537, GO:0007411=Reactome:REACT_18266, GO:0016199=GO_REF:0000024, GO:0030275=PMID:17848514, GO:0030673=GO_REF:0000019, GO:0050772=PMID:12504588, GO:0033600=PMID:18829537, GO:0007155=PMID:9608531, GO:0008046=PMID:9458045, GO:0007156=PMID:12504588} Q9Y6N7 Roundabout homolog 1 protein 20100203 {GO:0005515=IPI, GO:0005886=TAS, GO:0046982=IEA, GO:0009986=IDA, GO:0006919=IMP, GO:0002042=IMP, GO:0060763=IEA, GO:0035385=IMP, GO:0021836=IDA, GO:0007399=TAS, GO:0042802=IDA, GO:0050925=IDA, GO:0005887=TAS, GO:0070100=IMP, GO:0007411=TAS, GO:0016199=ISS, GO:0030275=IPI, GO:0030673=IEA, GO:0050772=IDA, GO:0033600=IMP, GO:0007155=TAS, GO:0008046=TAS, GO:0007156=IDA} Roundabout signaling pathway, activation of cysteine-type endopeptidase activity involved in apoptotic process, axon guidance, axon midline choice point recognition, cell adhesion, cell migration involved in sprouting angiogenesis, chemorepulsion involved in postnatal olfactory bulb interneuron migration, homophilic cell adhesion, mammary duct terminal end bud growth, negative regulation of chemokine-mediated signaling pathway, negative regulation of mammary gland epithelial cell proliferation, negative regulation of negative chemotaxis, nervous system development, positive regulation of axonogenesis axolemma, cell surface, integral to plasma membrane, plasma membrane LRR domain binding, axon guidance receptor activity, identical protein binding, protein binding, protein heterodimerization activity Human ROBO2 Reactome UniProtKB {GO:0031290=GO_REF:0000024, GO:0005515=PMID:15207848, GO:0001656=GO_REF:0000024, GO:0021891=GO_REF:0000024, GO:0001657=PMID:17357069, GO:0051964=GO_REF:0000024, GO:0046982=GO_REF:0000019, GO:0009986=PMID:12504588, GO:0061364=PMID:18566128, GO:0007417=PMID:9458045, GO:0032870=PMID:18566128, GO:0042802=PMID:12504588, GO:0050925=PMID:11748139, GO:0016020=GO_REF:0000002, GO:0007411=Reactome:REACT_18266, GO:0007420=PMID:10197527, GO:0016199=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0050772=PMID:12504588, GO:0030673=GO_REF:0000024, GO:0007155=GO_REF:0000002, GO:0007156=PMID:12504588, GO:0008046=GO_REF:0000024} Q9HCK4 Roundabout homolog 2 protein 20130301 {GO:0031290=ISS, GO:0005515=IPI, GO:0001656=ISS, GO:0021891=ISS, GO:0001657=IMP, GO:0051964=ISS, GO:0046982=IEA, GO:0009986=IDA, GO:0061364=IEP, GO:0007417=NAS, GO:0032870=IEP, GO:0042802=IDA, GO:0050925=IDA, GO:0016020=IEA, GO:0007411=TAS, GO:0007420=IEP, GO:0016199=ISS, GO:0016021=IEA, GO:0050772=IDA, GO:0030673=ISS, GO:0007155=IEA, GO:0007156=IDA, GO:0008046=ISS} apoptotic process involved in luteolysis, axon guidance, axon midline choice point recognition, brain development, cell adhesion, cellular response to hormone stimulus, central nervous system development, homophilic cell adhesion, metanephros development, negative regulation of negative chemotaxis, negative regulation of synapse assembly, olfactory bulb interneuron development, positive regulation of axonogenesis, retinal ganglion cell axon guidance, ureteric bud development axolemma, cell surface, integral to membrane, membrane axon guidance receptor activity, identical protein binding, protein binding, protein heterodimerization activity Human ROBO3 Reactome UniProtKB {GO:0030424=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0016199=GO_REF:0000024, GO:0007411=Reactome:REACT_18266, GO:0016021=PMID:15105459, GO:0001764=GO_REF:0000019, GO:0042803=GO_REF:0000019} Q96MS0 Roundabout homolog 3 protein 20090904 {GO:0030424=IEA, GO:0046982=IEA, GO:0016199=ISS, GO:0007411=TAS, GO:0016021=NAS, GO:0001764=IEA, GO:0042803=IEA} axon guidance, axon midline choice point recognition, neuron migration axon, integral to membrane protein heterodimerization activity, protein homodimerization activity Human ROBO4 UniProtKB UniProtKB {GO:0030334=PMID:15894287, GO:0030336=GO_REF:0000019, GO:0004872=PMID:14527427, GO:0016021=PMID:14527427, GO:0001525=PMID:15849270, GO:0030154=GO_REF:0000037, GO:0009897=GO_REF:0000019} Q8WZ75 Roundabout homolog 4 protein 20050526 {GO:0030334=NAS, GO:0030336=IEA, GO:0004872=TAS, GO:0016021=TAS, GO:0001525=IGI, GO:0030154=IEA, GO:0009897=IEA} angiogenesis, cell differentiation, negative regulation of cell migration, regulation of cell migration external side of plasma membrane, integral to membrane receptor activity Human ROCK1 BHF-UCL UniProtKB {GO:0005515=PMID:10652353, GO:0030036=GO_REF:0000019, GO:2000145=PMID:12778124, GO:0051492=PMID:12778124, GO:0007266=PMID:8798490, GO:0050900=PMID:12082081, GO:0050901=PMID:12082081, GO:0030155=PMID:12778124, GO:0051893=PMID:12778124, GO:0006921=Reactome:REACT_995, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_19389, GO:0006939=PMID:12778124, GO:0045616=PMID:19997641, GO:0043524=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0007411=Reactome:REACT_18266, GO:0032956=PMID:12778124, GO:0007159=PMID:12082081, GO:0022614=PMID:12082081, GO:0003383=GO_REF:0000019, GO:0005814=GO_REF:0000039, GO:0032060=GO_REF:0000019, GO:2000114=PMID:20803696, GO:0006915=Reactome:REACT_578, GO:0005524=GO_REF:0000037, GO:0007165=PMID:10436159, GO:0032059=GO_REF:0000039, GO:0004672=PMID:8798490, GO:0000139=GO_REF:0000039, GO:0004674=PMID:18694941, GO:0016525=PMID:19181962, GO:0017048=GO_REF:0000002, GO:0006468=PMID:10436159} Q13464 Rho-associated protein kinase 1 protein 20080620 {GO:0005515=IPI, GO:0030036=IEA, GO:2000145=TAS, GO:0051492=TAS, GO:0007266=TAS, GO:0050900=IDA, GO:0050901=IDA, GO:0030155=TAS, GO:0051893=TAS, GO:0006921=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0006939=TAS, GO:0045616=IMP, GO:0043524=IEA, GO:0005543=IEA, GO:0007411=TAS, GO:0032956=TAS, GO:0007159=IDA, GO:0022614=IDA, GO:0003383=IEA, GO:0005814=IEA, GO:0032060=IEA, GO:2000114=TAS, GO:0006915=TAS, GO:0005524=IEA, GO:0007165=TAS, GO:0032059=IEA, GO:0004672=TAS, GO:0000139=IEA, GO:0004674=IDA, GO:0016525=IMP, GO:0017048=IEA, GO:0006468=TAS} Rho protein signal transduction, actin cytoskeleton organization, apical constriction, apoptotic process, axon guidance, bleb assembly, cellular component disassembly involved in execution phase of apoptosis, leukocyte cell-cell adhesion, leukocyte migration, leukocyte tethering or rolling, membrane to membrane docking, negative regulation of angiogenesis, negative regulation of neuron apoptotic process, protein phosphorylation, regulation of actin cytoskeleton organization, regulation of cell adhesion, regulation of cell motility, regulation of establishment of cell polarity, regulation of focal adhesion assembly, regulation of keratinocyte differentiation, regulation of stress fiber assembly, signal transduction, smooth muscle contraction Golgi membrane, bleb, centriole, cytosol ATP binding, Rho GTPase binding, metal ion binding, phospholipid binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human ROCK2 Reactome UniProtKB {GO:0005515=PMID:17015463, GO:0030036=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:2000145=PMID:12778124, GO:0051492=PMID:12778124, GO:0005634=GO_REF:0000039, GO:0030155=PMID:12778124, GO:0051893=PMID:12778124, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_19389, GO:0035556=GO_REF:0000002, GO:0006939=PMID:12778124, GO:0000910=PMID:9933571, GO:0045616=PMID:19997641, GO:0005543=GO_REF:0000002, GO:0007411=Reactome:REACT_18266, GO:0032956=PMID:12778124, GO:0005813=PMID:17015463, GO:0010825=GO_REF:0000019, GO:2000114=PMID:20803696, GO:0001843=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0051298=PMID:17015463, GO:0005198=PMID:9933571, GO:0004674=PMID:16574662, GO:0016525=PMID:19181962, GO:0017048=GO_REF:0000002, GO:0006468=PMID:18559669, GO:0031616=GO_REF:0000019} O75116 Rho-associated protein kinase 2 protein 20130301 {GO:0005515=IPI, GO:0030036=IEA, GO:0005886=IEA, GO:2000145=TAS, GO:0051492=TAS, GO:0005634=IEA, GO:0030155=TAS, GO:0051893=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0035556=IEA, GO:0006939=TAS, GO:0000910=NAS, GO:0045616=IMP, GO:0005543=IEA, GO:0007411=TAS, GO:0032956=TAS, GO:0005813=IDA, GO:0010825=IEA, GO:2000114=TAS, GO:0001843=IEA, GO:0005524=IEA, GO:0051298=IMP, GO:0005198=NAS, GO:0004674=IDA, GO:0016525=IMP, GO:0017048=IEA, GO:0006468=IDA, GO:0031616=IEA} actin cytoskeleton organization, axon guidance, centrosome duplication, cytokinesis, intracellular signal transduction, negative regulation of angiogenesis, neural tube closure, positive regulation of centrosome duplication, protein phosphorylation, regulation of actin cytoskeleton organization, regulation of cell adhesion, regulation of cell motility, regulation of establishment of cell polarity, regulation of focal adhesion assembly, regulation of keratinocyte differentiation, regulation of stress fiber assembly, smooth muscle contraction centrosome, cytosol, nucleus, plasma membrane, spindle pole centrosome ATP binding, Rho GTPase binding, metal ion binding, phospholipid binding, protein binding, protein serine/threonine kinase activity, structural molecule activity Human ROGDI LIFEdb UniProtKB {GO:0005622=GO_REF:0000054, GO:0030097=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0005635=GO_REF:0000039} Q9GZN7 Protein rogdi homolog protein 20100607 {GO:0005622=IDA, GO:0030097=IEA, GO:0008284=IEA, GO:0005635=IEA} hemopoiesis, positive regulation of cell proliferation intracellular, nuclear envelope Human ROM1 PINC UniProtKB {GO:0005887=PMID:1610568, GO:0042622=GO_REF:0000019, GO:0007155=GO_REF:0000037, GO:0007601=GO_REF:0000002} Q03395 Rod outer segment membrane protein 1 protein 20030904 {GO:0005887=TAS, GO:0042622=IEA, GO:0007155=IEA, GO:0007601=IEA} cell adhesion, visual perception integral to plasma membrane, photoreceptor outer segment membrane Human ROPN1 InterPro UniProtKB {GO:0007165=GO_REF:0000002, GO:0008603=GO_REF:0000002} Q9HAT0 Ropporin-1A protein 20130413 {GO:0007165=IEA, GO:0008603=IEA} signal transduction cAMP-dependent protein kinase regulator activity Human InterPro:IPR003117 ROPN1B UniProtKB UniProtKB {GO:0008603=GO_REF:0000002, GO:0046982=PMID:11278869, GO:0031514=PMID:11278869, GO:0030159=PMID:11278869, GO:0007266=PMID:11278869, GO:0030317=PMID:11278869, GO:0007283=PMID:11278869, GO:0042803=PMID:11278869, GO:0000910=PMID:11278869, GO:0007165=GO_REF:0000002, GO:0005737=PMID:11278869, GO:0016337=PMID:11278869, GO:0007342=PMID:11278869, GO:0007340=PMID:11278869} Q9BZX4 Ropporin-1B protein 20031216 {GO:0008603=IEA, GO:0046982=IPI, GO:0031514=IDA, GO:0030159=NAS, GO:0007266=TAS, GO:0030317=TAS, GO:0007283=NAS, GO:0042803=NAS, GO:0000910=NAS, GO:0007165=IEA, GO:0005737=IDA, GO:0016337=NAS, GO:0007342=NAS, GO:0007340=NAS} Rho protein signal transduction, acrosome reaction, cell-cell adhesion, cytokinesis, fusion of sperm to egg plasma membrane, signal transduction, sperm motility, spermatogenesis cytoplasm, motile cilium cAMP-dependent protein kinase regulator activity, protein heterodimerization activity, protein homodimerization activity, receptor signaling complex scaffold activity Human ROPN1L BHF-UCL UniProtKB {GO:0005515=PMID:18421703, GO:0007165=GO_REF:0000002, GO:0005737=PMID:18421703, GO:0001539=PMID:18421703, GO:0008603=GO_REF:0000002, GO:0031514=PMID:18421703} Q96C74 Ropporin-1-like protein protein 20110221 {GO:0005515=IPI, GO:0007165=IEA, GO:0005737=IDA, GO:0001539=IDA, GO:0008603=IEA, GO:0031514=IDA} ciliary or flagellar motility, signal transduction cytoplasm, motile cilium cAMP-dependent protein kinase regulator activity, protein binding Human UniProtKB:O75969 ROR1 IntAct UniProtKB {GO:0005515=PMID:22439932, GO:0017147=PMID:18287027, GO:0005737=PMID:8875995, GO:0005886=PMID:8875995, GO:0005887=PMID:1334494, GO:0004714=GO_REF:0000003, GO:0005524=GO_REF:0000037, GO:0007169=GO_REF:0000002} Q01973 Tyrosine-protein kinase transmembrane receptor ROR1 protein 20130415 {GO:0005515=IPI, GO:0017147=IPI, GO:0005737=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0004714=IEA, GO:0005524=IEA, GO:0007169=IEA} transmembrane receptor protein tyrosine kinase signaling pathway cytoplasm, integral to plasma membrane, plasma membrane ATP binding, Wnt-protein binding, protein binding, transmembrane receptor protein tyrosine kinase activity Human UniProtKB:P12931 ROR2 IntAct UniProtKB {GO:0005515=PMID:22939624, GO:0017147=PMID:19486338, GO:0030335=PMID:19486338, GO:0008285=PMID:19486338, GO:0042472=GO_REF:0000019, GO:0001756=GO_REF:0000019, GO:0090263=GO_REF:0000019, GO:0007254=GO_REF:0000019, GO:0007275=PMID:1334494, GO:0005524=GO_REF:0000037, GO:0007223=GO_REF:0000019, GO:0030154=GO_REF:0000019, GO:0005109=GO_REF:0000019, GO:0007165=PMID:1334494, GO:0005887=PMID:1334494, GO:0001502=GO_REF:0000019, GO:0030538=GO_REF:0000019, GO:0004713=GO_REF:0000002, GO:0004714=GO_REF:0000003, GO:0045893=GO_REF:0000019, GO:0090090=GO_REF:0000019, GO:0007169=GO_REF:0000002, GO:0060071=GO_REF:0000019} Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 protein 20130415 {GO:0005515=IPI, GO:0017147=IPI, GO:0030335=IDA, GO:0008285=IMP, GO:0042472=IEA, GO:0001756=IEA, GO:0090263=IEA, GO:0007254=IEA, GO:0007275=TAS, GO:0005524=IEA, GO:0007223=IEA, GO:0030154=IEA, GO:0005109=IEA, GO:0007165=TAS, GO:0005887=TAS, GO:0001502=IEA, GO:0030538=IEA, GO:0004713=IEA, GO:0004714=IEA, GO:0045893=IEA, GO:0090090=IEA, GO:0007169=IEA, GO:0060071=IEA} JNK cascade, Wnt receptor signaling pathway, calcium modulating pathway, Wnt receptor signaling pathway, planar cell polarity pathway, cartilage condensation, cell differentiation, embryonic genitalia morphogenesis, inner ear morphogenesis, multicellular organismal development, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cell proliferation, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of cell migration, positive regulation of transcription, DNA-dependent, signal transduction, somitogenesis, transmembrane receptor protein tyrosine kinase signaling pathway integral to plasma membrane ATP binding, Wnt-protein binding, frizzled binding, protein binding, protein tyrosine kinase activity, transmembrane receptor protein tyrosine kinase activity Human UniProtKB:P08238 RORA GOC UniProtKB {GO:0005515=PMID:16713569, GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_15525, GO:0003700=PMID:17545671, GO:0043030=GO_REF:0000019, GO:0003707=GO_REF:0000002, GO:0005634=GO_REF:0000038, GO:0046068=GO_REF:0000019, GO:0006351=GO_REF:0000038, GO:0006809=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0007165=PMID:7926749, GO:0021702=GO_REF:0000019, GO:0045944=PMID:17545671, GO:0005654=Reactome:REACT_118635, GO:0008270=GO_REF:0000002, GO:0004879=GO_REF:0000002, GO:0030522=PMID:7926749} P35398 Nuclear receptor ROR-alpha protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0006367=TAS, GO:0003700=IDA, GO:0043030=IEA, GO:0003707=IEA, GO:0005634=IEA, GO:0046068=IEA, GO:0006351=IEA, GO:0006809=IEA, GO:0043565=IEA, GO:0007165=NAS, GO:0021702=IEA, GO:0045944=IDA, GO:0005654=TAS, GO:0008270=IEA, GO:0004879=IEA, GO:0030522=TAS} cGMP metabolic process, cerebellar Purkinje cell differentiation, gene expression, intracellular receptor signaling pathway, nitric oxide biosynthetic process, positive regulation of transcription from RNA polymerase II promoter, regulation of macrophage activation, signal transduction, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent nucleoplasm, nucleus ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity, zinc ion binding Human RORB GOC UniProtKB {GO:0010467=Reactome:REACT_71, GO:0006355=PMID:7935491, GO:0003700=GO_REF:0000024, GO:0006367=Reactome:REACT_15525, GO:0003707=GO_REF:0000002, GO:0043565=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_19207, GO:0004879=GO_REF:0000002, GO:0045893=GO_REF:0000024, GO:0007601=GO_REF:0000037, GO:0042462=GO_REF:0000024, GO:0030522=PMID:7935491} Q92753 Nuclear receptor ROR-beta protein 20130413 {GO:0010467=TAS, GO:0006355=TAS, GO:0003700=ISS, GO:0006367=TAS, GO:0003707=IEA, GO:0043565=ISS, GO:0008270=IEA, GO:0005654=TAS, GO:0004879=IEA, GO:0045893=ISS, GO:0007601=IEA, GO:0042462=ISS, GO:0030522=TAS} eye photoreceptor cell development, gene expression, intracellular receptor signaling pathway, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription initiation from RNA polymerase II promoter, visual perception nucleoplasm ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity, zinc ion binding Human RORC GOC UniProtKB {GO:0010467=Reactome:REACT_71, GO:0033077=GO_REF:0000019, GO:0006367=Reactome:REACT_15525, GO:0072539=GO_REF:0000019, GO:0003707=GO_REF:0000002, GO:0005634=GO_REF:0000038, GO:0048537=GO_REF:0000019, GO:0003677=PMID:7811290, GO:0048535=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0006468=GO_REF:0000019, GO:0005654=Reactome:REACT_19207, GO:0004879=GO_REF:0000002, GO:0030522=PMID:7811290} P51449 Nuclear receptor ROR-gamma protein 20130413 {GO:0010467=TAS, GO:0033077=IEA, GO:0006367=TAS, GO:0072539=IEA, GO:0003707=IEA, GO:0005634=IEA, GO:0048537=IEA, GO:0003677=TAS, GO:0048535=IEA, GO:0043565=IEA, GO:0008270=IEA, GO:0006468=IEA, GO:0005654=TAS, GO:0004879=IEA, GO:0030522=TAS} T cell differentiation in thymus, T-helper 17 cell differentiation, gene expression, intracellular receptor signaling pathway, lymph node development, mucosal-associated lymphoid tissue development, protein phosphorylation, transcription initiation from RNA polymerase II promoter nucleoplasm, nucleus DNA binding, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding, steroid hormone receptor activity, zinc ion binding Human ROS1 UniProtKB UniProtKB {GO:0032006=PMID:16885344, GO:0005886=GO_REF:0000039, GO:0008283=GO_REF:0000024, GO:0019903=PMID:16885344, GO:0007283=GO_REF:0000024, GO:0005524=GO_REF:0000038, GO:0030154=GO_REF:0000024, GO:0002066=GO_REF:0000024, GO:0016020=PMID:3785223, GO:0010629=GO_REF:0000019, GO:0016049=PMID:16885344, GO:0006468=PMID:16885344, GO:0004713=PMID:16885344, GO:0016021=GO_REF:0000038, GO:0004714=GO_REF:0000002, GO:0007169=GO_REF:0000002, GO:0070372=GO_REF:0000024, GO:0010966=GO_REF:0000019} Q5H8Y1 Proto-oncogene tyrosine-protein kinase ROS protein 20130413 {GO:0032006=IDA, GO:0005886=IEA, GO:0008283=ISS, GO:0019903=IPI, GO:0007283=ISS, GO:0005524=IEA, GO:0030154=ISS, GO:0002066=ISS, GO:0016020=TAS, GO:0010629=IEA, GO:0016049=IDA, GO:0006468=IDA, GO:0004713=IDA, GO:0016021=IEA, GO:0004714=IEA, GO:0007169=IEA, GO:0070372=ISS, GO:0010966=IEA} cell differentiation, cell growth, cell proliferation, columnar/cuboidal epithelial cell development, negative regulation of gene expression, protein phosphorylation, regulation of ERK1 and ERK2 cascade, regulation of TOR signaling cascade, regulation of phosphate transport, spermatogenesis, transmembrane receptor protein tyrosine kinase signaling pathway integral to membrane, membrane, plasma membrane ATP binding, protein phosphatase binding, protein tyrosine kinase activity, transmembrane receptor protein tyrosine kinase activity Human UniProtKB-KW:KW-0812 RP1 PINC UniProtKB {GO:0005515=PMID:21148103, GO:0008017=GO_REF:0000024, GO:0042461=GO_REF:0000024, GO:0035082=GO_REF:0000024, GO:0007603=PMID:10391211, GO:0046549=GO_REF:0000024, GO:0005875=GO_REF:0000024, GO:0005874=GO_REF:0000037, GO:0046548=GO_REF:0000024, GO:0071482=GO_REF:0000019, GO:0035085=GO_REF:0000039, GO:0045494=GO_REF:0000024, GO:0035556=GO_REF:0000002, GO:0035845=GO_REF:0000024, GO:0001917=PMID:11773008, GO:0032391=PMID:11767049, GO:0007601=PMID:10391211, GO:0001750=GO_REF:0000024} P56715 Oxygen-regulated protein 1 protein 20030904 {GO:0005515=IPI, GO:0008017=ISS, GO:0042461=ISS, GO:0035082=ISS, GO:0007603=TAS, GO:0046549=ISS, GO:0005875=ISS, GO:0005874=IEA, GO:0046548=ISS, GO:0071482=IEA, GO:0035085=IEA, GO:0045494=ISS, GO:0035556=IEA, GO:0035845=ISS, GO:0001917=IDA, GO:0032391=IDA, GO:0007601=TAS, GO:0001750=ISS} axoneme assembly, cellular response to light stimulus, intracellular signal transduction, photoreceptor cell development, photoreceptor cell maintenance, photoreceptor cell outer segment organization, phototransduction, visible light, retinal cone cell development, retinal rod cell development, visual perception cilium axoneme, microtubule, microtubule associated complex, photoreceptor connecting cilium, photoreceptor inner segment, photoreceptor outer segment microtubule binding, protein binding Human RP1L1 UniProtKB UniProtKB {GO:0035556=GO_REF:0000002, GO:0042461=GO_REF:0000024, GO:0030030=GO_REF:0000037, GO:0005874=GO_REF:0000037, GO:0032391=GO_REF:0000024, GO:0045494=GO_REF:0000024, GO:0035085=GO_REF:0000024, GO:0001750=GO_REF:0000024} Q8IWN7 Retinitis pigmentosa 1-like 1 protein protein 20110426 {GO:0035556=IEA, GO:0042461=ISS, GO:0030030=IEA, GO:0005874=IEA, GO:0032391=ISS, GO:0045494=ISS, GO:0035085=ISS, GO:0001750=ISS} cell projection organization, intracellular signal transduction, photoreceptor cell development, photoreceptor cell maintenance cilium axoneme, microtubule, photoreceptor connecting cilium, photoreceptor outer segment Human UniProtKB:Q8CGM2 RP2 GOC UniProtKB {GO:0005515=PMID:18376416, GO:0006241=GO_REF:0000002, GO:0005886=PMID:12417528, GO:0004550=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0005524=GO_REF:0000002, GO:0043547=PMID:18376416, GO:0006228=GO_REF:0000002, GO:0000902=GO_REF:0000002, GO:0006183=GO_REF:0000002, GO:0005929=GO_REF:0000039, GO:0005737=PMID:12417528, GO:0006457=PMID:9697692, GO:0051082=PMID:9697692, GO:0007023=PMID:11847227, GO:0007601=PMID:9697692, GO:0005096=PMID:18376416} O75695 Protein XRP2 protein 20130413 {GO:0005515=IPI, GO:0006241=IEA, GO:0005886=IDA, GO:0004550=IEA, GO:0005525=IEA, GO:0015031=IEA, GO:0005524=IEA, GO:0043547=IDA, GO:0006228=IEA, GO:0000902=IEA, GO:0006183=IEA, GO:0005929=IEA, GO:0005737=IDA, GO:0006457=TAS, GO:0051082=TAS, GO:0007023=IDA, GO:0007601=TAS, GO:0005096=IDA} CTP biosynthetic process, GTP biosynthetic process, UTP biosynthetic process, cell morphogenesis, positive regulation of GTPase activity, post-chaperonin tubulin folding pathway, protein folding, protein transport, visual perception cilium, cytoplasm, plasma membrane ATP binding, GTP binding, GTPase activator activity, nucleoside diphosphate kinase activity, protein binding, unfolded protein binding Human RP9 UniProtKB UniProtKB {GO:0005515=PMID:15652350, GO:0008380=PMID:15652350, GO:0005785=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q8TA86 Retinitis pigmentosa 9 protein protein 20050725 {GO:0005515=IPI, GO:0008380=TAS, GO:0005785=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA} RNA splicing nucleus, signal recognition particle receptor complex nucleic acid binding, protein binding, zinc ion binding Human UniProtKB:Q86X95 RPA1 HPA UniProtKB {GO:0005515=PMID:15965237, GO:0051276=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0015629=GO_REF:0000052, GO:0046872=GO_REF:0000037, GO:0006302=Reactome:REACT_2054, GO:0000084=Reactome:REACT_899, GO:0005737=GO_REF:0000052, GO:0006271=Reactome:REACT_932, GO:0000082=Reactome:REACT_1783, GO:0048873=GO_REF:0000019, GO:0003697=GO_REF:0000019, GO:0000723=Reactome:REACT_7970, GO:0000724=Reactome:REACT_1874, GO:0000722=Reactome:REACT_8027, GO:0006297=Reactome:REACT_1998, GO:0005662=PMID:16135809, GO:0030097=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0006310=PMID:8756712, GO:0000800=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0006260=Reactome:REACT_6769, GO:0006261=PMID:8756712, GO:0006281=Reactome:REACT_216, GO:0007126=GO_REF:0000019, GO:0006283=Reactome:REACT_1628, GO:0003682=GO_REF:0000019, GO:0016605=PMID:16135809, GO:0000730=Reactome:REACT_2141, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_8015, GO:0006289=Reactome:REACT_1826, GO:0000278=Reactome:REACT_152, GO:0000718=Reactome:REACT_311, GO:0001673=GO_REF:0000019, GO:0032201=Reactome:REACT_7961} P27694 Replication protein A 70 kDa DNA-binding subunit protein 20101115 {GO:0005515=IPI, GO:0051276=IEA, GO:0008284=IEA, GO:0005634=IDA, GO:0015629=IDA, GO:0046872=IEA, GO:0006302=TAS, GO:0000084=TAS, GO:0005737=IDA, GO:0006271=TAS, GO:0000082=TAS, GO:0048873=IEA, GO:0003697=IEA, GO:0000723=TAS, GO:0000724=TAS, GO:0000722=TAS, GO:0006297=TAS, GO:0005662=IPI, GO:0030097=IEA, GO:0005730=IDA, GO:0006310=TAS, GO:0000800=IEA, GO:0001701=IEA, GO:0006260=TAS, GO:0006261=TAS, GO:0006281=TAS, GO:0007126=IEA, GO:0006283=TAS, GO:0003682=IEA, GO:0016605=IDA, GO:0000730=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0006289=TAS, GO:0000278=TAS, GO:0000718=TAS, GO:0001673=IEA, GO:0032201=TAS} DNA recombinase assembly, DNA recombination, DNA repair, DNA replication, DNA strand elongation involved in DNA replication, DNA-dependent DNA replication, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, cell cycle checkpoint, chromosome organization, double-strand break repair, double-strand break repair via homologous recombination, hemopoiesis, homeostasis of number of cells within a tissue, in utero embryonic development, meiosis, mitotic cell cycle, nucleotide-excision repair, nucleotide-excision repair, DNA damage removal, nucleotide-excision repair, DNA gap filling, positive regulation of cell proliferation, telomere maintenance, telomere maintenance via recombination, telomere maintenance via semi-conservative replication, transcription-coupled nucleotide-excision repair DNA replication factor A complex, PML body, actin cytoskeleton, cytoplasm, lateral element, male germ cell nucleus, nucleolus, nucleoplasm, nucleus chromatin binding, metal ion binding, protein binding, single-stranded DNA binding Human RPA2 HPA UniProtKB {GO:0005515=PMID:20670893, GO:0005634=GO_REF:0000052, GO:0010569=PMID:20154705, GO:0006302=Reactome:REACT_2054, GO:0000084=Reactome:REACT_899, GO:0000082=Reactome:REACT_1783, GO:0006271=Reactome:REACT_932, GO:0003697=GO_REF:0000019, GO:0000723=Reactome:REACT_7970, GO:0000724=Reactome:REACT_1874, GO:0000722=Reactome:REACT_8027, GO:0006297=Reactome:REACT_1998, GO:0005662=GO_REF:0000019, GO:0019903=PMID:20154705, GO:0005730=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0006260=Reactome:REACT_6769, GO:0006261=PMID:2406247, GO:0047485=GO_REF:0000019, GO:0006281=Reactome:REACT_216, GO:0006283=Reactome:REACT_1628, GO:0016605=GO_REF:0000039, GO:0000730=Reactome:REACT_2141, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_8015, GO:0006289=Reactome:REACT_1826, GO:0000718=Reactome:REACT_311, GO:0000278=Reactome:REACT_152, GO:0032201=Reactome:REACT_7961} Q5TEJ7 Replication protein A 32 kDa subunit protein 20101115 {GO:0005515=IPI, GO:0005634=IDA, GO:0010569=IMP, GO:0006302=TAS, GO:0000084=TAS, GO:0000082=TAS, GO:0006271=TAS, GO:0003697=IEA, GO:0000723=TAS, GO:0000724=TAS, GO:0000722=TAS, GO:0006297=TAS, GO:0005662=IEA, GO:0019903=IPI, GO:0005730=IDA, GO:0003676=IEA, GO:0006260=TAS, GO:0006261=TAS, GO:0047485=IEA, GO:0006281=TAS, GO:0006283=TAS, GO:0016605=IEA, GO:0000730=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0006289=TAS, GO:0000718=TAS, GO:0000278=TAS, GO:0032201=TAS} DNA recombinase assembly, DNA repair, DNA replication, DNA strand elongation involved in DNA replication, DNA-dependent DNA replication, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, cell cycle checkpoint, double-strand break repair, double-strand break repair via homologous recombination, mitotic cell cycle, nucleotide-excision repair, nucleotide-excision repair, DNA damage removal, nucleotide-excision repair, DNA gap filling, regulation of double-strand break repair via homologous recombination, telomere maintenance, telomere maintenance via recombination, telomere maintenance via semi-conservative replication, transcription-coupled nucleotide-excision repair DNA replication factor A complex, PML body, nucleolus, nucleoplasm, nucleus nucleic acid binding, protein N-terminus binding, protein binding, protein phosphatase binding, single-stranded DNA binding NOT Human RPA3 HPA UniProtKB {GO:0005515=PMID:19338310, GO:0006302=Reactome:REACT_2054, GO:0000084=Reactome:REACT_899, GO:0006260=Reactome:REACT_6769, GO:0005737=GO_REF:0000052, GO:0006271=Reactome:REACT_932, GO:0000082=Reactome:REACT_1783, GO:0006281=Reactome:REACT_216, GO:0000723=Reactome:REACT_7970, GO:0003697=PMID:8454588, GO:0000724=Reactome:REACT_1874, GO:0006283=Reactome:REACT_1628, GO:0000730=Reactome:REACT_2141, GO:0000722=Reactome:REACT_8027, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_7949, GO:0006297=Reactome:REACT_1998, GO:0006289=Reactome:REACT_1826, GO:0000718=Reactome:REACT_311, GO:0000278=Reactome:REACT_152, GO:0005662=PMID:8454588, GO:0032201=Reactome:REACT_7961} P35244 Replication protein A 14 kDa subunit protein 20101115 {GO:0005515=IPI, GO:0006302=TAS, GO:0000084=TAS, GO:0006260=TAS, GO:0005737=IDA, GO:0006271=TAS, GO:0000082=TAS, GO:0006281=TAS, GO:0000723=TAS, GO:0003697=TAS, GO:0000724=TAS, GO:0006283=TAS, GO:0000730=TAS, GO:0000722=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0006297=TAS, GO:0006289=TAS, GO:0000718=TAS, GO:0000278=TAS, GO:0005662=TAS, GO:0032201=TAS} DNA recombinase assembly, DNA repair, DNA replication, DNA strand elongation involved in DNA replication, G1/S transition of mitotic cell cycle, S phase of mitotic cell cycle, cell cycle checkpoint, double-strand break repair, double-strand break repair via homologous recombination, mitotic cell cycle, nucleotide-excision repair, nucleotide-excision repair, DNA damage removal, nucleotide-excision repair, DNA gap filling, telomere maintenance, telomere maintenance via recombination, telomere maintenance via semi-conservative replication, transcription-coupled nucleotide-excision repair DNA replication factor A complex, cytoplasm, nucleoplasm protein binding, single-stranded DNA binding Human RPA4 Reactome UniProtKB {GO:0000082=Reactome:REACT_1783, GO:0003697=PMID:7760808, GO:0006270=PMID:7760808, GO:0033260=PMID:19116208, GO:0005654=Reactome:REACT_789, GO:0005634=PMID:19942684, GO:0000077=PMID:19942684, GO:0006289=PMID:19996105, GO:0000278=Reactome:REACT_152, GO:0005662=PMID:19116208} Q13156 Replication protein A 30 kDa subunit protein 20130213 {GO:0000082=TAS, GO:0003697=TAS, GO:0006270=TAS, GO:0033260=IDA, GO:0005654=TAS, GO:0005634=IDA, GO:0000077=IDA, GO:0006289=IDA, GO:0000278=TAS, GO:0005662=IDA} DNA damage checkpoint, DNA replication initiation, DNA replication involved in S phase, G1/S transition of mitotic cell cycle, mitotic cell cycle, nucleotide-excision repair DNA replication factor A complex, nucleoplasm, nucleus single-stranded DNA binding Human RPAIN HPA UniProtKB {GO:0006261=PMID:16135809, GO:0005737=GO_REF:0000039, GO:0006281=PMID:16135809, GO:0016605=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0006310=PMID:16135809, GO:0005634=GO_REF:0000052, GO:0006606=PMID:16135809, GO:0032403=PMID:16135809, GO:0046872=GO_REF:0000037} Q86UA6 RPA-interacting protein protein 20101115 {GO:0006261=IPI, GO:0005737=IEA, GO:0006281=IPI, GO:0016605=IEA, GO:0005730=IDA, GO:0006310=IPI, GO:0005634=IDA, GO:0006606=IDA, GO:0032403=IPI, GO:0046872=IEA} DNA recombination, DNA repair, DNA-dependent DNA replication, protein import into nucleus PML body, cytoplasm, nucleolus, nucleus metal ion binding, protein complex binding Human RPAP1 UniProtKB UniProtKB {GO:0003899=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037} Q9BWH6 RNA polymerase II-associated protein 1 protein 20130413 {GO:0003899=IEA, GO:0005634=IEA, GO:0003677=IEA} nucleus DNA binding, DNA-directed RNA polymerase activity Human UniProtKB-SubCell:SL-0191 RPAP2 UniProtKB UniProtKB {GO:0005737=PMID:22137580, GO:0070940=PMID:22137580, GO:0009301=PMID:22137580, GO:0016591=PMID:22231121, GO:0005634=PMID:22137580, GO:0046872=GO_REF:0000037, GO:0008420=PMID:22137580} Q8IXW5 Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 protein 20120127 {GO:0005737=IDA, GO:0070940=IMP, GO:0009301=IMP, GO:0016591=IDA, GO:0005634=IDA, GO:0046872=IEA, GO:0008420=IMP} dephosphorylation of RNA polymerase II C-terminal domain, snRNA transcription DNA-directed RNA polymerase II, holoenzyme, cytoplasm, nucleus CTD phosphatase activity, metal ion binding Human RPAP3 null null {} null null null null {} null null null RPE IntAct UniProtKB {GO:0004750=Reactome:REACT_11118, GO:0005975=Reactome:REACT_474, GO:0016857=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0048029=GO_REF:0000019, GO:0006098=Reactome:REACT_1859, GO:0042803=PMID:20923965, GO:0009052=GO_REF:0000019, GO:0046872=PMID:20923965, GO:0042802=PMID:20923965, GO:0005829=Reactome:REACT_11118, GO:0043231=GO_REF:0000019} Q96AT9 Ribulose-phosphate 3-epimerase protein 20130415 {GO:0004750=EXP, GO:0005975=TAS, GO:0016857=IEA, GO:0044281=TAS, GO:0048029=IEA, GO:0006098=TAS, GO:0042803=IPI, GO:0009052=IEA, GO:0046872=IDA, GO:0042802=IPI, GO:0005829=TAS, GO:0043231=IEA} carbohydrate metabolic process, pentose-phosphate shunt, pentose-phosphate shunt, non-oxidative branch, small molecule metabolic process cytosol, intracellular membrane-bounded organelle identical protein binding, metal ion binding, monosaccharide binding, protein homodimerization activity, racemase and epimerase activity, acting on carbohydrates and derivatives, ribulose-phosphate 3-epimerase activity Human UniProtKB:Q96AT9 RPE65 Reactome UniProtKB {GO:0008286=GO_REF:0000019, GO:0007603=Reactome:REACT_160125, GO:0005886=Reactome:REACT_160208, GO:0052885=GO_REF:0000003, GO:0005783=GO_REF:0000037, GO:0052884=GO_REF:0000003, GO:0060042=GO_REF:0000019, GO:0001523=Reactome:REACT_160156, GO:0046872=GO_REF:0000037, GO:0071257=GO_REF:0000019, GO:0042574=GO_REF:0000019, GO:0006776=PMID:9326941, GO:0031090=GO_REF:0000039, GO:0007468=GO_REF:0000019, GO:0007601=GO_REF:0000019, GO:0004744=GO_REF:0000019} Q16518 Retinoid isomerohydrolase protein 20130301 {GO:0008286=IEA, GO:0007603=TAS, GO:0005886=TAS, GO:0052885=IEA, GO:0005783=IEA, GO:0052884=IEA, GO:0060042=IEA, GO:0001523=TAS, GO:0046872=IEA, GO:0071257=IEA, GO:0042574=IEA, GO:0006776=TAS, GO:0031090=IEA, GO:0007468=IEA, GO:0007601=IEA, GO:0004744=IEA} cellular response to electrical stimulus, insulin receptor signaling pathway, phototransduction, visible light, regulation of rhodopsin gene expression, retina morphogenesis in camera-type eye, retinal metabolic process, retinoid metabolic process, visual perception, vitamin A metabolic process endoplasmic reticulum, organelle membrane, plasma membrane all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity, all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity, metal ion binding, retinal isomerase activity Human RPF1 UniProtKB UniProtKB {GO:0003723=PMID:11864606, GO:0006364=GO_REF:0000037, GO:0005730=PMID:12429849, GO:0019843=GO_REF:0000037} Q9H9Y2 Ribosome production factor 1 protein 20050722 {GO:0003723=IDA, GO:0006364=IEA, GO:0005730=IDA, GO:0019843=IEA} rRNA processing nucleolus RNA binding, rRNA binding Human RPF2 HPA UniProtKB {GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9H7B2 Ribosome production factor 2 homolog protein 20110516 {GO:0005730=IDA, GO:0005634=IDA} nucleolus, nucleus Human RPGR PINC UniProtKB {GO:0005515=PMID:19430481, GO:0005813=PMID:15772089, GO:0005794=GO_REF:0000024, GO:0036126=GO_REF:0000024, GO:0035085=GO_REF:0000039, GO:0006886=PMID:9990021, GO:0036064=GO_REF:0000024, GO:0005085=GO_REF:0000037, GO:0042384=PMID:21933838, GO:0042073=GO_REF:0000024, GO:0007601=PMID:9399904, GO:0050896=GO_REF:0000037, GO:0001750=PMID:12140192} Q92834 X-linked retinitis pigmentosa GTPase regulator protein 20030904 {GO:0005515=IPI, GO:0005813=IDA, GO:0005794=ISS, GO:0036126=ISS, GO:0035085=IEA, GO:0006886=TAS, GO:0036064=ISS, GO:0005085=IEA, GO:0042384=IMP, GO:0042073=ISS, GO:0007601=IMP, GO:0050896=IEA, GO:0001750=IDA} cilium assembly, intracellular protein transport, intraflagellar transport, response to stimulus, visual perception Golgi apparatus, centrosome, cilium axoneme, cilium basal body, photoreceptor outer segment, sperm flagellum guanyl-nucleotide exchange factor activity, protein binding Human RPGRIP1 UniProtKB UniProtKB {GO:0005515=PMID:21224891, GO:0005929=GO_REF:0000039, GO:0060041=GO_REF:0000019, GO:0005930=GO_REF:0000019, GO:0042462=GO_REF:0000019, GO:0007601=GO_REF:0000019, GO:0050896=GO_REF:0000037} Q96KN7 X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 protein 20110714 {GO:0005515=IPI, GO:0005929=IEA, GO:0060041=IEA, GO:0005930=IEA, GO:0042462=IEA, GO:0007601=IEA, GO:0050896=IEA} eye photoreceptor cell development, response to stimulus, retina development in camera-type eye, visual perception axoneme, cilium protein binding Human UniProtKB:O75161 RPGRIP1L MGI UniProtKB {GO:0005515=PMID:21565611, GO:0007368=GO_REF:0000019, GO:0031870=PMID:19464661, GO:0021532=GO_REF:0000019, GO:0035085=PMID:17558409, GO:0005737=PMID:17558409, GO:0021772=GO_REF:0000019, GO:0005911=PMID:21565611, GO:0043010=GO_REF:0000019, GO:0005932=PMID:17558409, GO:0005813=PMID:17558409, GO:0045744=PMID:19464661, GO:0001822=GO_REF:0000019, GO:0021549=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0060039=GO_REF:0000019, GO:0001889=GO_REF:0000019, GO:0005929=PMID:17558409, GO:0022038=GO_REF:0000019, GO:0042384=GO_REF:0000019, GO:0021670=GO_REF:0000019, GO:0008589=GO_REF:0000019, GO:0035116=GO_REF:0000019, GO:0060322=GO_REF:0000019, GO:0035115=GO_REF:0000019, GO:0005923=GO_REF:0000039, GO:0043584=GO_REF:0000019} Q68CZ1 Protein fantom protein 20070906 {GO:0005515=IPI, GO:0007368=IEA, GO:0031870=IPI, GO:0021532=IEA, GO:0035085=IDA, GO:0005737=IDA, GO:0021772=IEA, GO:0005911=IDA, GO:0043010=IEA, GO:0005932=IDA, GO:0005813=IDA, GO:0045744=IDA, GO:0001822=IEA, GO:0021549=IEA, GO:0001701=IEA, GO:0060039=IEA, GO:0001889=IEA, GO:0005929=IDA, GO:0022038=IEA, GO:0042384=IEA, GO:0021670=IEA, GO:0008589=IEA, GO:0035116=IEA, GO:0060322=IEA, GO:0035115=IEA, GO:0005923=IEA, GO:0043584=IEA} camera-type eye development, cerebellum development, cilium assembly, corpus callosum development, determination of left/right symmetry, embryonic forelimb morphogenesis, embryonic hindlimb morphogenesis, head development, in utero embryonic development, kidney development, lateral ventricle development, liver development, negative regulation of G-protein coupled receptor protein signaling pathway, neural tube patterning, nose development, olfactory bulb development, pericardium development, regulation of smoothened signaling pathway cell-cell junction, centrosome, cilium, cilium axoneme, cytoplasm, microtubule basal body, tight junction protein binding, thromboxane A2 receptor binding Human RPH3A IntAct UniProtKB {GO:0005515=PMID:11377421, GO:0005544=GO_REF:0000024, GO:0005215=GO_REF:0000002, GO:0017137=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0016020=GO_REF:0000039, GO:0005509=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0006886=GO_REF:0000002, GO:0046872=GO_REF:0000038, GO:0008021=GO_REF:0000002} Q9Y2J0 Rabphilin-3A protein 20130415 {GO:0005515=IPI, GO:0005544=ISS, GO:0005215=IEA, GO:0017137=IEA, GO:0030054=IEA, GO:0016020=IEA, GO:0005509=ISS, GO:0008270=IEA, GO:0006886=IEA, GO:0046872=IEA, GO:0008021=IEA} intracellular protein transport cell junction, membrane, synaptic vesicle Rab GTPase binding, calcium ion binding, calcium-dependent phospholipid binding, metal ion binding, protein binding, transporter activity, zinc ion binding Human UniProtKB:O14936 RPH3AL PINC UniProtKB {GO:0008092=PMID:9367993, GO:0017137=GO_REF:0000002, GO:0045744=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0050714=GO_REF:0000019, GO:0042593=GO_REF:0000019, GO:0006887=GO_REF:0000037, GO:0006886=GO_REF:0000002, GO:0017158=GO_REF:0000019, GO:0005737=PMID:9367993, GO:0030274=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0030667=GO_REF:0000019, GO:0030658=GO_REF:0000039} Q9UNE2 Rab effector Noc2 protein 20030904 {GO:0008092=TAS, GO:0017137=IEA, GO:0045744=IEA, GO:0042493=IEA, GO:0050714=IEA, GO:0042593=IEA, GO:0006887=IEA, GO:0006886=IEA, GO:0017158=IEA, GO:0005737=TAS, GO:0030274=IEA, GO:0008270=IEA, GO:0030667=IEA, GO:0030658=IEA} exocytosis, glucose homeostasis, intracellular protein transport, negative regulation of G-protein coupled receptor protein signaling pathway, positive regulation of protein secretion, regulation of calcium ion-dependent exocytosis, response to drug cytoplasm, secretory granule membrane, transport vesicle membrane LIM domain binding, Rab GTPase binding, cytoskeletal protein binding, zinc ion binding Human RPIA Reactome UniProtKB {GO:0005622=GO_REF:0000029, GO:0004751=PMID:7758956, GO:0019693=GO_REF:0000019, GO:0005975=Reactome:REACT_474, GO:0044281=Reactome:REACT_111217, GO:0006098=Reactome:REACT_1859, GO:0048029=GO_REF:0000019, GO:0009052=GO_REF:0000029, GO:0005829=Reactome:REACT_6907, GO:0043231=GO_REF:0000019} P49247 Ribose-5-phosphate isomerase protein 20130301 {GO:0005622=NAS, GO:0004751=NAS, GO:0019693=IEA, GO:0005975=TAS, GO:0044281=TAS, GO:0006098=TAS, GO:0048029=IEA, GO:0009052=NAS, GO:0005829=TAS, GO:0043231=IEA} carbohydrate metabolic process, pentose-phosphate shunt, pentose-phosphate shunt, non-oxidative branch, ribose phosphate metabolic process, small molecule metabolic process cytosol, intracellular, intracellular membrane-bounded organelle monosaccharide binding, ribose-5-phosphate isomerase activity Human RPL10 LIFEdb UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:9443083, GO:0016070=Reactome:REACT_21257, GO:0005783=GO_REF:0000054, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0005840=GO_REF:0000002, GO:0016032=Reactome:REACT_6145, GO:0022625=PMID:9443083, GO:0044267=Reactome:REACT_17015} P27635 60S ribosomal protein L10 protein 20100607 {GO:0010467=TAS, GO:0003735=IDA, GO:0016070=TAS, GO:0005783=IDA, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0005840=IEA, GO:0016032=TAS, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit, endoplasmic reticulum, ribosome structural constituent of ribosome Human RPL10A Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0003723=GO_REF:0000002, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0009653=PMID:7609734, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P62906 60S ribosomal protein L10a protein 20130213 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0003723=IEA, GO:0006614=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0009653=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0016032=TAS, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, anatomical structure morphogenesis, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit RNA binding, structural constituent of ribosome Human RPL10L LIFEdb UniProtKB {GO:0003735=GO_REF:0000002, GO:0005634=GO_REF:0000054, GO:0007283=PMID:12490704, GO:0022625=PMID:12490704, GO:0006412=GO_REF:0000002} Q96L21 60S ribosomal protein L10-like protein 20100607 {GO:0003735=IEA, GO:0005634=IDA, GO:0007283=IEP, GO:0022625=NAS, GO:0006412=IEA} spermatogenesis, translation cytosolic large ribosomal subunit, nucleus structural constituent of ribosome Human RPL11 InterPro UniProtKB {GO:0005515=PMID:15195100, GO:0010467=Reactome:REACT_71, GO:0034504=GO_REF:0000024, GO:0003723=PMID:7748210, GO:0006364=PMID:18697920, GO:0019058=Reactome:REACT_6167, GO:0006605=PMID:15195100, GO:0019843=GO_REF:0000037, GO:0006412=GO_REF:0000002, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0042273=PMID:18697920, GO:0003735=GO_REF:0000002, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006614=Reactome:REACT_115902, GO:0019083=Reactome:REACT_6152, GO:0005730=PMID:15195100, GO:0006415=Reactome:REACT_1986, GO:0005840=GO_REF:0000002, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} Q5VVC9 60S ribosomal protein L11 protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0034504=ISS, GO:0003723=TAS, GO:0006364=IMP, GO:0019058=TAS, GO:0006605=IMP, GO:0019843=IEA, GO:0006412=IEA, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0016032=TAS, GO:0042273=IMP, GO:0003735=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0006614=TAS, GO:0019083=TAS, GO:0005730=IDA, GO:0006415=TAS, GO:0005840=IEA, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, protein localization to nucleus, protein targeting, rRNA processing, ribosomal large subunit biogenesis, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit, nucleolus, ribosome RNA binding, protein binding, rRNA binding, structural constituent of ribosome Human InterPro:IPR002132|InterPro:IPR020929 RPL12 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0003723=GO_REF:0000037, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P30050 60S ribosomal protein L12 protein 20130213 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0003723=IEA, GO:0006614=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0016032=TAS, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit RNA binding, structural constituent of ribosome Human RPL13 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0003723=PMID:9582194, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0022626=PMID:9582194, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0005840=GO_REF:0000038, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P26373 60S ribosomal protein L13 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0003723=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0022626=TAS, GO:0000184=TAS, GO:0016032=TAS, GO:0005840=IEA, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit, cytosolic ribosome, ribosome RNA binding, protein binding, structural constituent of ribosome Human UniProtKB:P27986 RPL13A Reactome UniProtKB {GO:0017148=PMID:23071094, GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0015934=PMID:10580157, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_198, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:1901194=PMID:17218275, GO:0071346=PMID:15479637, GO:0030529=PMID:18809582, GO:0016032=Reactome:REACT_6145, GO:0005840=GO_REF:0000002, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P40429 60S ribosomal protein L13a protein 20130213 {GO:0017148=IDA, GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0015934=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:1901194=IDA, GO:0071346=IDA, GO:0030529=IDA, GO:0016032=TAS, GO:0005840=IEA, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, cellular response to interferon-gamma, gene expression, mRNA metabolic process, negative regulation of formation of translation preinitiation complex, negative regulation of translation, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit, large ribosomal subunit, ribonucleoprotein complex, ribosome structural constituent of ribosome Human RPL14 HPA UniProtKB {GO:0005515=PMID:11369516, GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006364=PMID:18697920, GO:0003723=PMID:9480843, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0005737=GO_REF:0000052, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0005840=GO_REF:0000002, GO:0042273=PMID:18697920, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P50914 60S ribosomal protein L14 protein 20080205 {GO:0005515=IPI, GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006364=IMP, GO:0003723=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0005737=IDA, GO:0000184=TAS, GO:0016032=TAS, GO:0005840=IEA, GO:0042273=IMP, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, rRNA processing, ribosomal large subunit biogenesis, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytoplasm, cytosol, cytosolic large ribosomal subunit, ribosome RNA binding, protein binding, structural constituent of ribosome Human RPL15 Reactome UniProtKB {GO:0005515=PMID:21612406, GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0003723=PMID:9582194, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0005840=PMID:9582194, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P61313 60S ribosomal protein L15 protein 20130213 {GO:0005515=IPI, GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0003723=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0016032=TAS, GO:0005840=TAS, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit, ribosome RNA binding, protein binding, structural constituent of ribosome Human RPL17 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0015934=GO_REF:0000002, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P18621 60S ribosomal protein L17 protein 20130213 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0015934=IEA, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0016032=TAS, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit, large ribosomal subunit structural constituent of ribosome Human RPL18 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0003723=PMID:8218404, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0005840=GO_REF:0000038, GO:0016032=Reactome:REACT_6145, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} Q07020 60S ribosomal protein L18 protein 20130213 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0003723=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0005840=IEA, GO:0016032=TAS, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit, ribosome RNA binding, structural constituent of ribosome Human RPL18A Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0003723=PMID:9582194, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0005840=GO_REF:0000002, GO:0016032=Reactome:REACT_6145, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} Q02543 60S ribosomal protein L18a protein 20130213 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0003723=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0005840=IEA, GO:0016032=TAS, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit, ribosome RNA binding, structural constituent of ribosome Human RPL19 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0003723=PMID:1577483, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0005840=GO_REF:0000038, GO:0016032=Reactome:REACT_6145, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P84098 60S ribosomal protein L19 protein 20130213 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0003723=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0005840=IEA, GO:0016032=TAS, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit, ribosome RNA binding, structural constituent of ribosome Human RPL21 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0003723=PMID:7772601, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0005840=GO_REF:0000002, GO:0016032=Reactome:REACT_6145, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P46778 60S ribosomal protein L21 protein 20130213 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0003723=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0005840=IEA, GO:0016032=TAS, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit, ribosome RNA binding, structural constituent of ribosome Human RPL22 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0003723=GO_REF:0000037, GO:0046632=GO_REF:0000019, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0005737=PMID:8135813, GO:0000184=Reactome:REACT_75886, GO:0030529=PMID:18809582, GO:0016032=Reactome:REACT_6145, GO:0005840=GO_REF:0000038, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015, GO:0008201=GO_REF:0000019} P35268 60S ribosomal protein L22 protein 20130213 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0003723=IEA, GO:0046632=IEA, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0005737=IDA, GO:0000184=TAS, GO:0030529=IDA, GO:0016032=TAS, GO:0005840=IEA, GO:0022625=IDA, GO:0044267=TAS, GO:0008201=IEA} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, alpha-beta T cell differentiation, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytoplasm, cytosol, cytosolic large ribosomal subunit, ribonucleoprotein complex, ribosome RNA binding, heparin binding, structural constituent of ribosome Human RPL22L1 UniProtKB UniProtKB {GO:0003735=GO_REF:0000002, GO:0005840=GO_REF:0000037, GO:0006412=GO_REF:0000002} Q6P5R6 60S ribosomal protein L22-like 1 protein 20130413 {GO:0003735=IEA, GO:0005840=IEA, GO:0006412=IEA} translation ribosome structural constituent of ribosome Human UniProtKB-KW:KW-0689 RPL23 HPA UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0005730=GO_REF:0000019, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0005737=GO_REF:0000052, GO:0006610=PMID:1874450, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0005840=PMID:1874450, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P62829 60S ribosomal protein L23 protein 20080205 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0005730=IEA, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0005737=IDA, GO:0006610=NAS, GO:0000184=TAS, GO:0016032=TAS, GO:0005840=NAS, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, ribosomal protein import into nucleus, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytoplasm, cytosol, cytosolic large ribosomal subunit, nucleolus, ribosome structural constituent of ribosome Human RPL23A Reactome UniProtKB {GO:0005515=PMID:9687515, GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0008283=PMID:9053844, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0005634=PMID:9687515, GO:0019843=GO_REF:0000037, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0006414=Reactome:REACT_1477, GO:0005829=Reactome:REACT_115921, GO:0000166=GO_REF:0000002, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0005840=GO_REF:0000038, GO:0031932=GO_REF:0000024, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P62750 60S ribosomal protein L23a protein 20130213 {GO:0005515=IPI, GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0008283=IMP, GO:0019083=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0005634=IDA, GO:0019843=IEA, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0006414=TAS, GO:0005829=TAS, GO:0000166=IEA, GO:0000184=TAS, GO:0016032=TAS, GO:0005840=IEA, GO:0031932=ISS, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cell proliferation, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription TORC2 complex, cytosol, cytosolic large ribosomal subunit, nucleus, ribosome nucleotide binding, protein binding, rRNA binding, structural constituent of ribosome Human RPL24 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0003723=PMID:9582194, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0005840=GO_REF:0000038, GO:0016032=Reactome:REACT_6145, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P83731 60S ribosomal protein L24 protein 20130213 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0003723=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0005840=IEA, GO:0016032=TAS, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit, ribosome RNA binding, structural constituent of ribosome Human RPL26 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006364=PMID:18697920, GO:0003723=PMID:8479925, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0015934=GO_REF:0000002, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0042273=PMID:18697920, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P61254 60S ribosomal protein L26 protein 20130213 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006364=IMP, GO:0003723=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0015934=IEA, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0016032=TAS, GO:0042273=IMP, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, rRNA processing, ribosomal large subunit biogenesis, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit, large ribosomal subunit RNA binding, structural constituent of ribosome Human RPL26L1 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=GO_REF:0000002, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0015934=GO_REF:0000002, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0044267=Reactome:REACT_17015} Q9UNX3 60S ribosomal protein L26-like 1 protein 20130213 {GO:0010467=TAS, GO:0003735=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0015934=IEA, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0016032=TAS, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, large ribosomal subunit structural constituent of ribosome Human RPL27 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_75891, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0030529=PMID:18809582, GO:0005840=PMID:8148381, GO:0016032=Reactome:REACT_6145, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P61353 60S ribosomal protein L27 protein 20130213 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0030529=IDA, GO:0005840=TAS, GO:0016032=TAS, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit, ribonucleoprotein complex, ribosome structural constituent of ribosome Human RPL27A IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0003723=PMID:7772601, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0005840=GO_REF:0000038, GO:0016032=Reactome:REACT_6145, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P46776 60S ribosomal protein L27a protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0003723=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0005840=IEA, GO:0016032=TAS, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit, ribosome RNA binding, protein binding, structural constituent of ribosome Human UniProtKB:P13984 RPL28 HPA UniProtKB {GO:0005515=PMID:20434207, GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0003723=PMID:7772601, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0005737=GO_REF:0000052, GO:0000184=Reactome:REACT_75886, GO:0005840=GO_REF:0000002, GO:0016032=Reactome:REACT_6145, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P46779 60S ribosomal protein L28 protein 20120912 {GO:0005515=IPI, GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0003723=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0005737=IDA, GO:0000184=TAS, GO:0005840=IEA, GO:0016032=TAS, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytoplasm, cytosol, cytosolic large ribosomal subunit, ribosome RNA binding, protein binding, structural constituent of ribosome Human RPL29 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0007566=PMID:8662616, GO:0019083=Reactome:REACT_6152, GO:0003723=PMID:8597591, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0005840=GO_REF:0000002, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015, GO:0008201=GO_REF:0000037} P47914 60S ribosomal protein L29 protein 20130213 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0007566=TAS, GO:0019083=TAS, GO:0003723=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0016032=TAS, GO:0005840=IEA, GO:0022625=IDA, GO:0044267=TAS, GO:0008201=IEA} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, embryo implantation, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit, ribosome RNA binding, heparin binding, structural constituent of ribosome Human RPL3 HPA UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0003723=PMID:2891103, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0005730=GO_REF:0000052, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0005737=GO_REF:0000052, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0005840=GO_REF:0000038, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P39023 60S ribosomal protein L3 protein 20100326 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0003723=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0005730=IDA, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0005737=IDA, GO:0000184=TAS, GO:0016032=TAS, GO:0005840=IEA, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytoplasm, cytosol, cytosolic large ribosomal subunit, nucleolus, ribosome RNA binding, structural constituent of ribosome Human RPL30 HPA UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0003723=PMID:1577483, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0005737=GO_REF:0000052, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0005840=GO_REF:0000002, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P62888 60S ribosomal protein L30 protein 20080205 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0003723=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0005737=IDA, GO:0000184=TAS, GO:0016032=TAS, GO:0005840=IEA, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytoplasm, cytosol, cytosolic large ribosomal subunit, ribosome RNA binding, structural constituent of ribosome Human RPL31 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0003723=PMID:2780320, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0005840=GO_REF:0000002, GO:0016032=Reactome:REACT_6145, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P62899 60S ribosomal protein L31 protein 20130213 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0003723=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0005840=IEA, GO:0016032=TAS, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit, ribosome RNA binding, structural constituent of ribosome Human RPL32 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0005840=GO_REF:0000002, GO:0016032=Reactome:REACT_6145, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P62910 60S ribosomal protein L32 protein 20130213 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0005840=IEA, GO:0016032=TAS, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit, ribosome structural constituent of ribosome Human RPL34 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0003723=PMID:7490091, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P49207 60S ribosomal protein L34 protein 20130213 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0003723=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0016032=TAS, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit RNA binding, structural constituent of ribosome Human RPL35 HPA UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0005730=PMID:2891103, GO:0003729=PMID:2891103, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0005737=GO_REF:0000052, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0005840=GO_REF:0000002, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P42766 60S ribosomal protein L35 protein 20080818 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0005730=TAS, GO:0003729=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0005737=IDA, GO:0000184=TAS, GO:0016032=TAS, GO:0005840=IEA, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytoplasm, cytosol, cytosolic large ribosomal subunit, nucleolus, ribosome mRNA binding, structural constituent of ribosome Human RPL35A Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0000049=GO_REF:0000037, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006364=PMID:18697920, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0005840=GO_REF:0000002, GO:0042273=PMID:18697920, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P18077 60S ribosomal protein L35a protein 20130213 {GO:0010467=TAS, GO:0003735=NAS, GO:0000049=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006364=IMP, GO:0006614=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0016032=TAS, GO:0005840=IEA, GO:0042273=IMP, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, rRNA processing, ribosomal large subunit biogenesis, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit, ribosome structural constituent of ribosome, tRNA binding Human RPL36 HPA UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0005730=GO_REF:0000054, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0005737=GO_REF:0000052, GO:0000184=Reactome:REACT_75886, GO:0005840=GO_REF:0000038, GO:0016032=Reactome:REACT_6145, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} Q9Y3U8 60S ribosomal protein L36 protein 20120912 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0005730=IDA, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0005737=IDA, GO:0000184=TAS, GO:0005840=IEA, GO:0016032=TAS, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytoplasm, cytosol, cytosolic large ribosomal subunit, nucleolus, ribosome structural constituent of ribosome Human RPL36A Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0005737=GO_REF:0000029, GO:0000184=Reactome:REACT_75886, GO:0005840=PMID:3542712, GO:0016032=Reactome:REACT_6145, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P83881 60S ribosomal protein L36a protein 20130213 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0005737=NAS, GO:0000184=TAS, GO:0005840=NAS, GO:0016032=TAS, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytoplasm, cytosol, cytosolic large ribosomal subunit, ribosome structural constituent of ribosome Human RPL36AL UniProtKB UniProtKB {GO:0003735=GO_REF:0000002, GO:0005840=GO_REF:0000037, GO:0006412=GO_REF:0000002} Q969Q0 60S ribosomal protein L36a-like protein 20130413 {GO:0003735=IEA, GO:0005840=IEA, GO:0006412=IEA} translation ribosome structural constituent of ribosome Human UniProtKB-KW:KW-0689 RPL37 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0003723=PMID:7545944, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0019843=GO_REF:0000037, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0046872=GO_REF:0000037, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0005840=GO_REF:0000038, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P61927 60S ribosomal protein L37 protein 20130213 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0003723=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0019843=IEA, GO:0006415=TAS, GO:0006412=TAS, GO:0046872=IEA, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0016032=TAS, GO:0005840=IEA, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit, ribosome RNA binding, metal ion binding, rRNA binding, structural constituent of ribosome Human RPL37A UniProtKB UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=GO_REF:0000002, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0005840=GO_REF:0000038, GO:0016032=Reactome:REACT_6145, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} Q6P4E4 60S ribosomal protein L37a protein 20130413 {GO:0010467=TAS, GO:0003735=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=IEA, GO:0046872=IEA, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0005840=IEA, GO:0016032=TAS, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit, ribosome metal ion binding, structural constituent of ribosome Human UniProtKB-KW:KW-0689 RPL38 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0007605=GO_REF:0000019, GO:0003723=PMID:9375793, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0001503=GO_REF:0000019, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0005840=GO_REF:0000038, GO:0042474=GO_REF:0000019, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P63173 60S ribosomal protein L38 protein 20130213 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0007605=IEA, GO:0003723=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0001503=IEA, GO:0000184=TAS, GO:0016032=TAS, GO:0005840=IEA, GO:0042474=IEA, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, middle ear morphogenesis, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, ossification, sensory perception of sound, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit, ribosome RNA binding, structural constituent of ribosome Human RPL39 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0003723=PMID:8764829, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P62891 60S ribosomal protein L39 protein 20130213 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0003723=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0016032=TAS, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit RNA binding, structural constituent of ribosome Human RPL3L Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0003723=PMID:8921388, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0005840=PMID:8921388, GO:0016032=Reactome:REACT_6145, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} Q92901 60S ribosomal protein L3-like protein 20130213 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0003723=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0005840=TAS, GO:0016032=TAS, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit, ribosome RNA binding, structural constituent of ribosome Human RPL4 HPA UniProtKB {GO:0005515=PMID:23275563, GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0003723=PMID:8268230, GO:0006614=Reactome:REACT_115902, GO:0005730=GO_REF:0000052, GO:0019058=Reactome:REACT_6167, GO:0005634=GO_REF:0000052, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0005737=GO_REF:0000052, GO:0000184=Reactome:REACT_75886, GO:0030529=PMID:18809582, GO:0016032=Reactome:REACT_6145, GO:0005840=GO_REF:0000002, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P36578 60S ribosomal protein L4 protein 20101115 {GO:0005515=IPI, GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0003723=TAS, GO:0006614=TAS, GO:0005730=IDA, GO:0019058=TAS, GO:0005634=IDA, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0005737=IDA, GO:0000184=TAS, GO:0030529=IDA, GO:0016032=TAS, GO:0005840=IEA, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytoplasm, cytosol, cytosolic large ribosomal subunit, nucleolus, nucleus, ribonucleoprotein complex, ribosome RNA binding, protein binding, structural constituent of ribosome Human RPL41 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0003723=PMID:1326959, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P62945 60S ribosomal protein L41 protein 20130213 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0003723=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0016032=TAS, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit RNA binding, structural constituent of ribosome Human RPL5 InterPro UniProtKB {GO:0005515=PMID:20434207, GO:0010467=Reactome:REACT_71, GO:0003723=PMID:7772601, GO:0006364=PMID:18697920, GO:0019058=Reactome:REACT_6167, GO:0005634=PMID:9687515, GO:0006412=GO_REF:0000002, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0042273=PMID:18697920, GO:0008097=GO_REF:0000002, GO:0003735=GO_REF:0000002, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006614=Reactome:REACT_115902, GO:0019083=Reactome:REACT_6152, GO:0005730=GO_REF:0000039, GO:0006415=Reactome:REACT_1986, GO:0030529=PMID:18809582, GO:0005840=GO_REF:0000002, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} Q5T7N0 60S ribosomal protein L5 protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0003723=TAS, GO:0006364=IMP, GO:0019058=TAS, GO:0005634=IDA, GO:0006412=IEA, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0016032=TAS, GO:0042273=IMP, GO:0008097=IEA, GO:0003735=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0006614=TAS, GO:0019083=TAS, GO:0005730=IEA, GO:0006415=TAS, GO:0030529=IDA, GO:0005840=IEA, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, rRNA processing, ribosomal large subunit biogenesis, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit, nucleolus, nucleus, ribonucleoprotein complex, ribosome 5S rRNA binding, RNA binding, protein binding, structural constituent of ribosome Human InterPro:IPR005485 RPL6 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0006355=PMID:8457378, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0003723=PMID:8479925, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0003677=PMID:8457378, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0005840=GO_REF:0000038, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} Q02878 60S ribosomal protein L6 protein 20130213 {GO:0010467=TAS, GO:0006355=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0003723=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0003677=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0016032=TAS, GO:0005840=IEA, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, regulation of transcription, DNA-dependent, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit, ribosome DNA binding, RNA binding, structural constituent of ribosome Human RPL7 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0006364=PMID:18697920, GO:0003723=PMID:8441630, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0003729=PMID:8441630, GO:0006412=Reactome:REACT_1014, GO:0003677=PMID:8441630, GO:0042803=PMID:8441630, GO:0006413=Reactome:REACT_2159, GO:0006414=Reactome:REACT_1477, GO:0005829=Reactome:REACT_115921, GO:0000184=Reactome:REACT_75886, GO:0030529=PMID:18809582, GO:0016032=Reactome:REACT_6145, GO:0042273=PMID:18697920, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P18124 60S ribosomal protein L7 protein 20130213 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0006364=IMP, GO:0003723=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0003729=IDA, GO:0006412=TAS, GO:0003677=IDA, GO:0042803=IPI, GO:0006413=TAS, GO:0006414=TAS, GO:0005829=TAS, GO:0000184=TAS, GO:0030529=IDA, GO:0016032=TAS, GO:0042273=IMP, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, rRNA processing, ribosomal large subunit biogenesis, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit, ribonucleoprotein complex DNA binding, RNA binding, mRNA binding, protein homodimerization activity, structural constituent of ribosome Human RPL7A UniProtKB UniProtKB {GO:0005515=PMID:15303970, GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0042254=GO_REF:0000002, GO:0003723=PMID:8360149, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0016020=PMID:10848616, GO:0000184=Reactome:REACT_75886, GO:0042788=PMID:10848616, GO:0005840=GO_REF:0000038, GO:0016032=Reactome:REACT_6145, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} Q5T8U3 60S ribosomal protein L7a protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0042254=IEA, GO:0003723=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0016020=IDA, GO:0000184=TAS, GO:0042788=IDA, GO:0005840=IEA, GO:0016032=TAS, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, ribosome biogenesis, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit, membrane, polysomal ribosome, ribosome RNA binding, protein binding, structural constituent of ribosome Human UniProtKB-KW:KW-0689 RPL7L1 UniProtKB UniProtKB {GO:0005840=GO_REF:0000037} Q6DKI1 60S ribosomal protein L7-like 1 protein 20130413 {GO:0005840=IEA} ribosome Human UniProtKB-KW:KW-0689 RPL8 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0003723=PMID:7506540, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0019843=GO_REF:0000037, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0005840=GO_REF:0000038, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P62917 60S ribosomal protein L8 protein 20130213 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0003723=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0019843=IEA, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0016032=TAS, GO:0005840=IEA, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit, ribosome RNA binding, rRNA binding, structural constituent of ribosome Human RPL9 HPA UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0003723=PMID:8597601, GO:0019058=Reactome:REACT_6167, GO:0005730=GO_REF:0000052, GO:0019843=GO_REF:0000002, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0005737=GO_REF:0000052, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0005840=PMID:8597601, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P32969 60S ribosomal protein L9 protein 20080205 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0003723=TAS, GO:0019058=TAS, GO:0005730=IDA, GO:0019843=IEA, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0005737=IDA, GO:0000184=TAS, GO:0016032=TAS, GO:0005840=TAS, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytoplasm, cytosol, cytosolic large ribosomal subunit, nucleolus, ribosome RNA binding, rRNA binding, structural constituent of ribosome Human RPLP0 HPA UniProtKB {GO:0005515=PMID:15303970, GO:0010467=Reactome:REACT_71, GO:0003735=GO_REF:0000002, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0042254=GO_REF:0000002, GO:0003723=PMID:3323886, GO:0019058=Reactome:REACT_6167, GO:0005634=PMID:19188445, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0000184=Reactome:REACT_75886, GO:0019048=GO_REF:0000037, GO:0030529=PMID:17289661, GO:0016032=Reactome:REACT_6145, GO:0005840=GO_REF:0000038, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} Q3B7A4 60S acidic ribosomal protein P0 protein 20080205 {GO:0005515=IPI, GO:0010467=TAS, GO:0003735=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0042254=IEA, GO:0003723=TAS, GO:0019058=TAS, GO:0005634=IDA, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=IEA, GO:0005737=IDA, GO:0000184=TAS, GO:0019048=IEA, GO:0030529=IDA, GO:0016032=TAS, GO:0005840=IEA, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, ribosome biogenesis, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription, virus-host interaction cytoplasm, cytosol, cytosolic large ribosomal subunit, nucleus, ribonucleoprotein complex, ribosome RNA binding, protein binding, structural constituent of ribosome Human RPLP1 HPA UniProtKB {GO:0005515=PMID:12054647, GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0003723=PMID:3323886, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0005737=GO_REF:0000052, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P05386 60S acidic ribosomal protein P1 protein 20080205 {GO:0005515=IPI, GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0003723=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0005737=IDA, GO:0000184=TAS, GO:0016032=TAS, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytoplasm, cytosol, cytosolic large ribosomal subunit RNA binding, protein binding, structural constituent of ribosome Human RPLP2 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:12962325, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0003723=PMID:3323886, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0006414=Reactome:REACT_1477, GO:0005829=Reactome:REACT_115921, GO:0000184=Reactome:REACT_75886, GO:0005840=GO_REF:0000002, GO:0016032=Reactome:REACT_6145, GO:0022625=PMID:12962325, GO:0044267=Reactome:REACT_17015} P05387 60S acidic ribosomal protein P2 protein 20130213 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0003723=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0006414=TAS, GO:0005829=TAS, GO:0000184=TAS, GO:0005840=IEA, GO:0016032=TAS, GO:0022625=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic large ribosomal subunit, ribosome RNA binding, structural constituent of ribosome Human RPN1 Reactome UniProtKB {GO:0005791=GO_REF:0000024, GO:0042470=GO_REF:0000039, GO:0010467=Reactome:REACT_71, GO:0005783=GO_REF:0000002, GO:0006614=Reactome:REACT_115902, GO:0006412=Reactome:REACT_1014, GO:0004579=PMID:15835887, GO:0005789=Reactome:REACT_22208, GO:0006486=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0008250=PMID:15835887, GO:0044267=Reactome:REACT_17015, GO:0006464=PMID:10660554, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} P04843 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 protein 20130213 {GO:0005791=ISS, GO:0042470=IEA, GO:0010467=TAS, GO:0005783=IEA, GO:0006614=TAS, GO:0006412=TAS, GO:0004579=TAS, GO:0005789=TAS, GO:0006486=IEA, GO:0016021=IEA, GO:0008250=TAS, GO:0044267=TAS, GO:0006464=TAS, GO:0043687=TAS, GO:0018279=TAS} SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, cellular protein modification process, gene expression, post-translational protein modification, protein N-linked glycosylation via asparagine, protein glycosylation, translation endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, melanosome, oligosaccharyltransferase complex, rough endoplasmic reticulum dolichyl-diphosphooligosaccharide-protein glycotransferase activity Human RPN2 InterPro UniProtKB {GO:0005791=GO_REF:0000019, GO:0010467=Reactome:REACT_71, GO:0005783=GO_REF:0000052, GO:0042493=GO_REF:0000019, GO:0006614=Reactome:REACT_115902, GO:0000421=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0006412=Reactome:REACT_1014, GO:0004579=GO_REF:0000002, GO:0005789=Reactome:REACT_22208, GO:0043022=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0008250=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0006464=PMID:10660554, GO:0043687=Reactome:REACT_22161, GO:0018279=GO_REF:0000002} Q5JYR7 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 protein 20130413 {GO:0005791=IEA, GO:0010467=TAS, GO:0005783=IDA, GO:0042493=IEA, GO:0006614=TAS, GO:0000421=IEA, GO:0007568=IEA, GO:0005634=IDA, GO:0006412=TAS, GO:0004579=IEA, GO:0005789=TAS, GO:0043022=IEA, GO:0016021=IEA, GO:0008250=IEA, GO:0044267=TAS, GO:0006464=TAS, GO:0043687=TAS, GO:0018279=IEA} SRP-dependent cotranslational protein targeting to membrane, aging, cellular protein metabolic process, cellular protein modification process, gene expression, post-translational protein modification, protein N-linked glycosylation via asparagine, response to drug, translation autophagic vacuole membrane, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, nucleus, oligosaccharyltransferase complex, rough endoplasmic reticulum dolichyl-diphosphooligosaccharide-protein glycotransferase activity, ribosome binding Human InterPro:IPR008814 RPP14 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0004526=GO_REF:0000003, GO:0003723=PMID:10024167, GO:0006631=GO_REF:0000037, GO:0016491=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0016829=GO_REF:0000037, GO:0008033=GO_REF:0000037} P86397 Hydroxyacyl-thioester dehydratase type 2, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0004526=IEA, GO:0003723=TAS, GO:0006631=IEA, GO:0016491=IEA, GO:0005634=IEA, GO:0016829=IEA, GO:0008033=IEA} fatty acid metabolic process, tRNA processing mitochondrion, nucleus RNA binding, lyase activity, oxidoreductase activity, ribonuclease P activity Human UniProtKB-SubCell:SL-0173 RPP21 UniProtKB UniProtKB {GO:0004526=GO_REF:0000003, GO:0042493=PMID:18291362, GO:0005730=GO_REF:0000039, GO:0008033=GO_REF:0000037} Q9H633 Ribonuclease P protein subunit p21 protein 20100506 {GO:0004526=IEA, GO:0042493=IEP, GO:0005730=IEA, GO:0008033=IEA} response to drug, tRNA processing nucleolus ribonuclease P activity Human RPP25 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005515=PMID:15096576, GO:0005813=GO_REF:0000052, GO:0004526=GO_REF:0000003, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008033=GO_REF:0000037} Q9BUL9 Ribonuclease P protein subunit p25 protein 20120912 {GO:0005739=IDA, GO:0005515=IPI, GO:0005813=IDA, GO:0004526=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008033=IEA} tRNA processing centrosome, mitochondrion, nucleolus, nucleus RNA binding, protein binding, ribonuclease P activity Human RPP30 InterPro UniProtKB {GO:0004526=GO_REF:0000003, GO:0004540=GO_REF:0000002, GO:0005634=PMID:9630247, GO:0005655=PMID:9630247, GO:0008033=GO_REF:0000002} Q5VU11 Ribonuclease P protein subunit p30 protein 20130413 {GO:0004526=IEA, GO:0004540=IEA, GO:0005634=TAS, GO:0005655=TAS, GO:0008033=IEA} tRNA processing nucleolar ribonuclease P complex, nucleus ribonuclease P activity, ribonuclease activity Human InterPro:IPR002738 RPP38 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0004526=GO_REF:0000003, GO:0005634=PMID:9630247, GO:0005655=PMID:9630247, GO:0008033=GO_REF:0000037} P78345 Ribonuclease P protein subunit p38 protein 20130415 {GO:0005515=IPI, GO:0004526=IEA, GO:0005634=TAS, GO:0005655=TAS, GO:0008033=IEA} tRNA processing nucleolar ribonuclease P complex, nucleus protein binding, ribonuclease P activity Human UniProtKB:P16333 RPP40 PINC UniProtKB {GO:0004526=GO_REF:0000003, GO:0005634=PMID:9630247, GO:0005655=PMID:9630247, GO:0008033=GO_REF:0000037} O75818 Ribonuclease P protein subunit p40 protein 20030904 {GO:0004526=IEA, GO:0005634=TAS, GO:0005655=TAS, GO:0008033=IEA} tRNA processing nucleolar ribonuclease P complex, nucleus ribonuclease P activity Human RPRD1A UniProtKB UniProtKB {GO:0070940=PMID:22231121, GO:0016591=PMID:22231121} Q96P16 Regulation of nuclear pre-mRNA domain-containing protein 1A protein 20120127 {GO:0070940=IMP, GO:0016591=IDA} dephosphorylation of RNA polymerase II C-terminal domain DNA-directed RNA polymerase II, holoenzyme Human RPRD1B IntAct UniProtKB {GO:0005515=PMID:22264791, GO:0008284=PMID:22264791, GO:0070940=PMID:22231121, GO:0045944=PMID:22264791, GO:0016591=PMID:22231121, GO:0000993=PMID:22264791, GO:0005634=PMID:22264791, GO:0010564=PMID:22264791, GO:0006351=GO_REF:0000037} Q9NQG5 Regulation of nuclear pre-mRNA domain-containing protein 1B protein 20130415 {GO:0005515=IPI, GO:0008284=IDA, GO:0070940=IMP, GO:0045944=IDA, GO:0016591=IDA, GO:0000993=IDA, GO:0005634=IDA, GO:0010564=IDA, GO:0006351=IEA} dephosphorylation of RNA polymerase II C-terminal domain, positive regulation of cell proliferation, positive regulation of transcription from RNA polymerase II promoter, regulation of cell cycle process, transcription, DNA-dependent DNA-directed RNA polymerase II, holoenzyme, nucleus RNA polymerase II core binding, protein binding Human UniProtKB:P24928 RPRD2 UniProtKB UniProtKB {GO:0016591=PMID:22231121} Q5VT52 Regulation of nuclear pre-mRNA domain-containing protein 2 protein 20120127 {GO:0016591=IDA} DNA-directed RNA polymerase II, holoenzyme Human RPRM UniProtKB UniProtKB {GO:0007346=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0007050=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q9NS64 Protein reprimo protein 20130413 {GO:0007346=IEA, GO:0005737=IEA, GO:0007050=IEA, GO:0016021=IEA} cell cycle arrest, regulation of mitotic cell cycle cytoplasm, integral to membrane Human UniProtKB-SubCell:SL-0086 RPS10 Reactome UniProtKB {GO:0005515=PMID:20159986, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0005730=PMID:20159986, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0022627=PMID:8706699, GO:0005840=PMID:7772601, GO:0016032=Reactome:REACT_6145, GO:0044267=Reactome:REACT_17015} P46783 40S ribosomal protein S10 protein 20130213 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0005730=IDA, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0022627=IDA, GO:0005840=NAS, GO:0016032=TAS, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic small ribosomal subunit, nucleolus, ribosome protein binding Human RPS11 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=GO_REF:0000002, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0019843=GO_REF:0000037, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0022627=PMID:8706699, GO:0005840=PMID:3267208, GO:0016032=Reactome:REACT_6145, GO:0044267=Reactome:REACT_17015} P62280 40S ribosomal protein S11 protein 20130213 {GO:0010467=TAS, GO:0003735=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0019843=IEA, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0022627=IDA, GO:0005840=NAS, GO:0016032=TAS, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic small ribosomal subunit, ribosome rRNA binding, structural constituent of ribosome Human RPS12 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=GO_REF:0000002, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0003674=GO_REF:0000015, GO:0000184=Reactome:REACT_75886, GO:0022627=PMID:1861993, GO:0016032=Reactome:REACT_6145, GO:0044267=Reactome:REACT_17015} P25398 40S ribosomal protein S12 protein 20130213 {GO:0010467=TAS, GO:0003735=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0003674=ND, GO:0000184=TAS, GO:0022627=NAS, GO:0016032=TAS, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic small ribosomal subunit molecular_function, structural constituent of ribosome Human RPS13 IntAct UniProtKB {GO:0005515=PMID:12054647, GO:0010467=Reactome:REACT_71, GO:0003735=GO_REF:0000002, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0005730=PMID:17881366, GO:0005634=PMID:17881366, GO:0006415=Reactome:REACT_1986, GO:0003729=PMID:17881366, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0022627=PMID:8706699, GO:0033119=PMID:17881366, GO:0016032=Reactome:REACT_6145, GO:0005840=PMID:8332508, GO:0044267=Reactome:REACT_17015} P62277 40S ribosomal protein S13 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0003735=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0006415=TAS, GO:0003729=IDA, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0022627=IDA, GO:0033119=IDA, GO:0016032=TAS, GO:0005840=NAS, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, negative regulation of RNA splicing, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic small ribosomal subunit, nucleolus, nucleus, ribosome mRNA binding, protein binding, structural constituent of ribosome Human UniProtKB:Q53EL6 RPS14 GOC UniProtKB {GO:0048027=PMID:7867928, GO:0010467=Reactome:REACT_71, GO:0003723=GO_REF:0000024, GO:0019058=Reactome:REACT_6167, GO:0045182=PMID:3683397, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0030490=GO_REF:0000024, GO:0005739=GO_REF:0000019, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0000028=PMID:9152021, GO:0003735=GO_REF:0000002, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006614=Reactome:REACT_115902, GO:0019083=Reactome:REACT_6152, GO:0005730=PMID:9152021, GO:0000122=PMID:7867928, GO:0006415=Reactome:REACT_1986, GO:0006417=PMID:3683397, GO:0022627=PMID:8706699, GO:0030218=PMID:18202658, GO:0005840=GO_REF:0000002, GO:0044267=Reactome:REACT_17015} P62263 40S ribosomal protein S14 protein 20130413 {GO:0048027=IDA, GO:0010467=TAS, GO:0003723=ISS, GO:0019058=TAS, GO:0045182=IMP, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0030490=ISS, GO:0005739=IEA, GO:0000184=TAS, GO:0016032=TAS, GO:0000028=IMP, GO:0003735=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0006614=TAS, GO:0019083=TAS, GO:0005730=IDA, GO:0000122=IDA, GO:0006415=TAS, GO:0006417=IMP, GO:0022627=IDA, GO:0030218=IMP, GO:0005840=IEA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, erythrocyte differentiation, gene expression, mRNA metabolic process, maturation of SSU-rRNA, negative regulation of transcription from RNA polymerase II promoter, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, regulation of translation, ribosomal small subunit assembly, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic small ribosomal subunit, mitochondrion, nucleolus, ribosome RNA binding, mRNA 5'-UTR binding, structural constituent of ribosome, translation regulator activity Human RPS15 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0006364=PMID:18697920, GO:0003723=GO_REF:0000002, GO:0015935=GO_REF:0000002, GO:0019058=Reactome:REACT_6167, GO:0005634=PMID:2159154, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0042274=PMID:18697920, GO:0003735=GO_REF:0000002, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006614=Reactome:REACT_115902, GO:0019083=Reactome:REACT_6152, GO:0006415=Reactome:REACT_1986, GO:0003677=PMID:2159154, GO:0022627=PMID:8706699, GO:0005840=GO_REF:0000002, GO:0005654=PMID:16037817, GO:0044267=Reactome:REACT_17015, GO:0000056=PMID:16037817} P62841 40S ribosomal protein S15 protein 20130213 {GO:0010467=TAS, GO:0006364=IMP, GO:0003723=IEA, GO:0015935=IEA, GO:0019058=TAS, GO:0005634=NAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0016032=TAS, GO:0042274=IMP, GO:0003735=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0006614=TAS, GO:0019083=TAS, GO:0006415=TAS, GO:0003677=NAS, GO:0022627=IDA, GO:0005840=IEA, GO:0005654=NAS, GO:0044267=TAS, GO:0000056=IMP} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, rRNA processing, ribosomal small subunit biogenesis, ribosomal small subunit export from nucleus, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic small ribosomal subunit, nucleoplasm, nucleus, ribosome, small ribosomal subunit DNA binding, RNA binding, structural constituent of ribosome Human RPS15A Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0008284=PMID:15108328, GO:0003735=PMID:9582194, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0003723=PMID:9582194, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0009615=PMID:15108328, GO:0006412=Reactome:REACT_1014, GO:0045787=PMID:15108328, GO:0006413=Reactome:REACT_2159, GO:0006414=Reactome:REACT_1477, GO:0005829=Reactome:REACT_115921, GO:0005739=GO_REF:0000019, GO:0005737=PMID:15108328, GO:0000184=Reactome:REACT_75886, GO:0022627=PMID:8706699, GO:0016032=Reactome:REACT_6145, GO:0005840=GO_REF:0000002, GO:0044267=Reactome:REACT_17015} P62244 40S ribosomal protein S15a protein 20130213 {GO:0010467=TAS, GO:0008284=IDA, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0003723=NAS, GO:0019058=TAS, GO:0006415=TAS, GO:0009615=IDA, GO:0006412=TAS, GO:0045787=IDA, GO:0006413=TAS, GO:0006414=TAS, GO:0005829=TAS, GO:0005739=IEA, GO:0005737=IDA, GO:0000184=TAS, GO:0022627=IDA, GO:0016032=TAS, GO:0005840=IEA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, positive regulation of cell cycle, positive regulation of cell proliferation, response to virus, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytoplasm, cytosol, cytosolic small ribosomal subunit, mitochondrion, ribosome RNA binding, structural constituent of ribosome Human RPS16 InterPro UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=GO_REF:0000002, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0006364=PMID:18697920, GO:0003723=PMID:17881366, GO:0019058=Reactome:REACT_6167, GO:0015935=PMID:15883184, GO:0006415=Reactome:REACT_1986, GO:0006412=GO_REF:0000002, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0022627=PMID:2016298, GO:0016032=Reactome:REACT_6145, GO:0005840=GO_REF:0000002, GO:0042274=PMID:18697920, GO:0044267=Reactome:REACT_17015} Q6IPX4 RPS16 protein protein 20130413 {GO:0010467=TAS, GO:0003735=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0006364=IMP, GO:0003723=IDA, GO:0019058=TAS, GO:0015935=IDA, GO:0006415=TAS, GO:0006412=IEA, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0022627=NAS, GO:0016032=TAS, GO:0005840=IEA, GO:0042274=IMP, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, rRNA processing, ribosomal small subunit biogenesis, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic small ribosomal subunit, ribosome, small ribosomal subunit RNA binding, structural constituent of ribosome Human InterPro:IPR000754 RPS17 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:17647292, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0006364=PMID:18697920, GO:0019058=Reactome:REACT_6167, GO:0034101=PMID:17647292, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0006414=Reactome:REACT_1477, GO:0005829=Reactome:REACT_115921, GO:0000184=Reactome:REACT_75886, GO:0022627=PMID:8706699, GO:0016032=Reactome:REACT_6145, GO:0005840=PMID:3240863, GO:0042274=PMID:18697920, GO:0044267=Reactome:REACT_17015, GO:0000028=GO_REF:0000033} P08708 40S ribosomal protein S17 protein 20130213 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0006364=IMP, GO:0019058=TAS, GO:0034101=IMP, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0006414=TAS, GO:0005829=TAS, GO:0000184=TAS, GO:0022627=IDA, GO:0016032=TAS, GO:0005840=NAS, GO:0042274=IMP, GO:0044267=TAS, GO:0000028=ISS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, erythrocyte homeostasis, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, rRNA processing, ribosomal small subunit assembly, ribosomal small subunit biogenesis, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic small ribosomal subunit, ribosome structural constituent of ribosome Human RPS17L UniProtKB UniProtKB {GO:0003735=GO_REF:0000002, GO:0005840=GO_REF:0000037, GO:0006412=GO_REF:0000002} P0CW22 40S ribosomal protein S17-like protein 20130413 {GO:0003735=IEA, GO:0005840=IEA, GO:0006412=IEA} translation ribosome structural constituent of ribosome Human UniProtKB-KW:KW-0689 RPS18 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0005581=GO_REF:0000038, GO:0003735=GO_REF:0000033, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0003723=GO_REF:0000002, GO:0042254=GO_REF:0000033, GO:0019058=Reactome:REACT_6167, GO:0015935=PMID:15883184, GO:0019843=GO_REF:0000037, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0006414=Reactome:REACT_1477, GO:0005829=Reactome:REACT_115921, GO:0003674=GO_REF:0000015, GO:0000184=Reactome:REACT_75886, GO:0022627=PMID:8706699, GO:0016032=Reactome:REACT_6145, GO:0005840=PMID:8441687, GO:0044267=Reactome:REACT_17015} P62269 40S ribosomal protein S18 protein 20130213 {GO:0010467=TAS, GO:0005581=IEA, GO:0003735=IBA, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0003723=IEA, GO:0042254=IBA, GO:0019058=TAS, GO:0015935=IDA, GO:0019843=IEA, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0006414=TAS, GO:0005829=TAS, GO:0003674=ND, GO:0000184=TAS, GO:0022627=IDA, GO:0016032=TAS, GO:0005840=NAS, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, ribosome biogenesis, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription collagen, cytosol, cytosolic small ribosomal subunit, ribosome, small ribosomal subunit RNA binding, molecular_function, rRNA binding, structural constituent of ribosome Human RPS19 BHF-UCL UniProtKB {GO:0005515=PMID:16266891, GO:0000462=PMID:17053056, GO:0010467=Reactome:REACT_71, GO:0006364=PMID:18697920, GO:0019058=Reactome:REACT_6167, GO:0009991=PMID:16289379, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0030490=PMID:16990592, GO:0005737=PMID:17517689, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0042274=PMID:18697920, GO:0000028=PMID:17053056, GO:0003735=PMID:15883184, GO:0051262=PMID:11226885, GO:0019901=PMID:16266891, GO:0016070=Reactome:REACT_21257, GO:0017134=PMID:11716516, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0005730=PMID:16289379, GO:0006415=Reactome:REACT_1986, GO:0022627=PMID:8706699, GO:0030218=PMID:16289379, GO:0005840=PMID:17517689, GO:0044267=Reactome:REACT_17015, GO:0051272=PMID:16289379} P39019 40S ribosomal protein S19 protein 20130211 {GO:0005515=IPI, GO:0000462=IMP, GO:0010467=TAS, GO:0006364=IMP, GO:0019058=TAS, GO:0009991=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0030490=IMP, GO:0005737=IDA, GO:0000184=TAS, GO:0016032=TAS, GO:0042274=IMP, GO:0000028=IMP, GO:0003735=IDA, GO:0051262=IDA, GO:0019901=IPI, GO:0016070=TAS, GO:0017134=IPI, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0005730=IDA, GO:0006415=TAS, GO:0022627=IDA, GO:0030218=IMP, GO:0005840=IDA, GO:0044267=TAS, GO:0051272=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, erythrocyte differentiation, gene expression, mRNA metabolic process, maturation of SSU-rRNA, maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, positive regulation of cellular component movement, protein tetramerization, rRNA processing, response to extracellular stimulus, ribosomal small subunit assembly, ribosomal small subunit biogenesis, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytoplasm, cytosol, cytosolic small ribosomal subunit, nucleolus, ribosome fibroblast growth factor binding, protein binding, protein kinase binding, structural constituent of ribosome Human UniProtKB:P09038 RPS19BP1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005654=PMID:16289379} Q86WX3 Active regulator of SIRT1 protein 20111111 {GO:0005737=IDA, GO:0005730=IDA, GO:0005654=ISS} cytoplasm, nucleolus, nucleoplasm Human RPS2 Reactome UniProtKB {GO:0005515=PMID:15473865, GO:0010467=Reactome:REACT_71, GO:0003735=PMID:15883184, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0017134=PMID:16263090, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0003723=GO_REF:0000002, GO:0019058=Reactome:REACT_6167, GO:0015935=GO_REF:0000002, GO:0005730=PMID:16263090, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0006414=Reactome:REACT_1477, GO:0005829=Reactome:REACT_115921, GO:0000184=Reactome:REACT_75886, GO:0022627=PMID:8706699, GO:0016032=Reactome:REACT_6145, GO:0005840=GO_REF:0000002, GO:0005654=PMID:16263090, GO:0044267=Reactome:REACT_17015} P15880 40S ribosomal protein S2 protein 20130213 {GO:0005515=IPI, GO:0010467=TAS, GO:0003735=IDA, GO:0016070=TAS, GO:0016071=TAS, GO:0017134=IPI, GO:0019083=TAS, GO:0006614=TAS, GO:0003723=IEA, GO:0019058=TAS, GO:0015935=IEA, GO:0005730=IDA, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0006414=TAS, GO:0005829=TAS, GO:0000184=TAS, GO:0022627=IDA, GO:0016032=TAS, GO:0005840=IEA, GO:0005654=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic small ribosomal subunit, nucleolus, nucleoplasm, ribosome, small ribosomal subunit RNA binding, fibroblast growth factor binding, protein binding, structural constituent of ribosome Human RPS20 HPA UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:8479924, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0003723=PMID:8479924, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0015935=GO_REF:0000002, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0005737=GO_REF:0000052, GO:0000184=Reactome:REACT_75886, GO:0022627=PMID:8706699, GO:0016032=Reactome:REACT_6145, GO:0005840=GO_REF:0000002, GO:0044267=Reactome:REACT_17015} P60866 40S ribosomal protein S20 protein 20080205 {GO:0010467=TAS, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0003723=NAS, GO:0006614=TAS, GO:0019058=TAS, GO:0015935=IEA, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0005737=IDA, GO:0000184=TAS, GO:0022627=IDA, GO:0016032=TAS, GO:0005840=IEA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytoplasm, cytosol, cytosolic small ribosomal subunit, ribosome, small ribosomal subunit RNA binding, structural constituent of ribosome Human RPS21 UniProtKB UniProtKB {GO:0010467=Reactome:REACT_71, GO:0000461=GO_REF:0000033, GO:0003735=GO_REF:0000002, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0015935=PMID:15883184, GO:0006415=Reactome:REACT_1986, GO:0006412=GO_REF:0000002, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0005737=GO_REF:0000052, GO:0047485=PMID:10079194, GO:0000184=Reactome:REACT_75886, GO:0022627=PMID:8706699, GO:0005840=GO_REF:0000038, GO:0016032=Reactome:REACT_6145, GO:0042274=GO_REF:0000033, GO:0000447=GO_REF:0000033, GO:0044267=Reactome:REACT_17015} Q9BYK2 40S ribosomal protein S21 protein 20130413 {GO:0010467=TAS, GO:0000461=IBA, GO:0003735=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0015935=IDA, GO:0006415=TAS, GO:0006412=IEA, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0005737=IDA, GO:0047485=IPI, GO:0000184=TAS, GO:0022627=IDA, GO:0005840=IEA, GO:0016032=TAS, GO:0042274=IBA, GO:0000447=IBA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA), gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, ribosomal small subunit biogenesis, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytoplasm, cytosol, cytosolic small ribosomal subunit, ribosome, small ribosomal subunit protein N-terminus binding, structural constituent of ribosome Human UniProtKB-KW:KW-0689 RPS23 IntAct UniProtKB {GO:0005515=PMID:20434207, GO:0010467=Reactome:REACT_71, GO:0003735=GO_REF:0000002, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0015935=GO_REF:0000002, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0003674=GO_REF:0000015, GO:0000184=Reactome:REACT_75886, GO:0022627=PMID:8706699, GO:0016032=Reactome:REACT_6145, GO:0005840=PMID:8415000, GO:0044267=Reactome:REACT_17015} P62266 40S ribosomal protein S23 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0003735=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0015935=IEA, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0003674=ND, GO:0000184=TAS, GO:0022627=IDA, GO:0016032=TAS, GO:0005840=NAS, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic small ribosomal subunit, ribosome, small ribosomal subunit molecular_function, protein binding, structural constituent of ribosome Human UniProtKB:P43146 RPS24 HPA UniProtKB {GO:0000462=GO_REF:0000033, GO:0010467=Reactome:REACT_71, GO:0006364=PMID:18230666, GO:0015935=GO_REF:0000024, GO:0019058=Reactome:REACT_6167, GO:0034101=PMID:18230666, GO:0005634=GO_REF:0000052, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0005737=GO_REF:0000052, GO:0000166=GO_REF:0000002, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0042274=PMID:18230666, GO:0003735=PMID:18412286, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0005730=GO_REF:0000033, GO:0006415=Reactome:REACT_1986, GO:0022627=PMID:8706699, GO:0005840=GO_REF:0000038, GO:0031369=GO_REF:0000024, GO:0044267=Reactome:REACT_17015} P62847 40S ribosomal protein S24 protein 20120912 {GO:0000462=IBA, GO:0010467=TAS, GO:0006364=IMP, GO:0015935=ISS, GO:0019058=TAS, GO:0034101=IMP, GO:0005634=IDA, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0005737=IDA, GO:0000166=IEA, GO:0000184=TAS, GO:0016032=TAS, GO:0042274=IMP, GO:0003735=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0005730=IBA, GO:0006415=TAS, GO:0022627=IDA, GO:0005840=IEA, GO:0031369=ISS, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, erythrocyte homeostasis, gene expression, mRNA metabolic process, maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, rRNA processing, ribosomal small subunit biogenesis, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytoplasm, cytosol, cytosolic small ribosomal subunit, nucleolus, nucleus, ribosome, small ribosomal subunit nucleotide binding, structural constituent of ribosome, translation initiation factor binding Human RPS25 HPA UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=GO_REF:0000019, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0003723=PMID:10050887, GO:0019058=Reactome:REACT_6167, GO:0015935=PMID:15883184, GO:0005730=PMID:10050887, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0005737=GO_REF:0000052, GO:0000184=Reactome:REACT_75886, GO:0022627=PMID:8706699, GO:0016032=Reactome:REACT_6145, GO:0005840=PMID:8020948, GO:0044267=Reactome:REACT_17015, GO:0000028=GO_REF:0000019} P62851 40S ribosomal protein S25 protein 20101115 {GO:0010467=TAS, GO:0003735=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0003723=NAS, GO:0019058=TAS, GO:0015935=IDA, GO:0005730=IDA, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0005737=IDA, GO:0000184=TAS, GO:0022627=IDA, GO:0016032=TAS, GO:0005840=NAS, GO:0044267=TAS, GO:0000028=IEA} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, ribosomal small subunit assembly, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytoplasm, cytosol, cytosolic small ribosomal subunit, nucleolus, ribosome, small ribosomal subunit RNA binding, structural constituent of ribosome Human RPS26 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0010467=Reactome:REACT_71, GO:0003735=GO_REF:0000002, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0015935=PMID:15883184, GO:0003729=PMID:15716004, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0022627=PMID:8706699, GO:0033119=PMID:15716004, GO:0016032=Reactome:REACT_6145, GO:0044267=Reactome:REACT_17015} P62854 40S ribosomal protein S26 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0003735=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0015935=IDA, GO:0003729=IDA, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0022627=IDA, GO:0033119=IDA, GO:0016032=TAS, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, negative regulation of RNA splicing, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic small ribosomal subunit, small ribosomal subunit mRNA binding, protein binding, structural constituent of ribosome Human UniProtKB:Q969E8 RPS27 InterPro UniProtKB {GO:0005515=PMID:21170087, GO:0000236=Reactome:REACT_682, GO:0010467=Reactome:REACT_71, GO:0008283=PMID:8407955, GO:0019058=Reactome:REACT_6167, GO:0005634=PMID:8407955, GO:0006412=GO_REF:0000002, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_150414, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6145, GO:0003735=GO_REF:0000002, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006614=Reactome:REACT_115902, GO:0019083=Reactome:REACT_6152, GO:0006415=Reactome:REACT_1986, GO:0003677=PMID:8908372, GO:0022627=PMID:8706699, GO:0005840=GO_REF:0000002, GO:0008270=PMID:8407955, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0044267=Reactome:REACT_17015} Q5T4L4 40S ribosomal protein S27 protein 20130413 {GO:0005515=IPI, GO:0000236=TAS, GO:0010467=TAS, GO:0008283=NAS, GO:0019058=TAS, GO:0005634=IDA, GO:0006412=IEA, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0000087=TAS, GO:0016032=TAS, GO:0003735=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0006614=TAS, GO:0019083=TAS, GO:0006415=TAS, GO:0003677=NAS, GO:0022627=IDA, GO:0005840=IEA, GO:0008270=NAS, GO:0000278=TAS, GO:0000090=TAS, GO:0044267=TAS} M phase of mitotic cell cycle, RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cell proliferation, cellular protein metabolic process, gene expression, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic small ribosomal subunit, nucleus, ribosome DNA binding, protein binding, structural constituent of ribosome, zinc ion binding Human InterPro:IPR000592 RPS27A Reactome UniProtKB {GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0007220=Reactome:REACT_2001, GO:0006367=Reactome:REACT_12627, GO:0019221=Reactome:REACT_25229, GO:0007249=Reactome:REACT_25351, GO:0019058=Reactome:REACT_6167, GO:0051403=Reactome:REACT_21308, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0006414=Reactome:REACT_1477, GO:0002756=Reactome:REACT_6809, GO:0034220=Reactome:REACT_25300, GO:0007219=Reactome:REACT_118859, GO:0007173=Reactome:REACT_9417, GO:0002755=Reactome:REACT_27215, GO:0007179=Reactome:REACT_120850, GO:0043123=Reactome:REACT_24918, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0034134=Reactome:REACT_7980, GO:0042059=Reactome:REACT_12484, GO:0033554=Reactome:REACT_120956, GO:0000122=Reactome:REACT_121111, GO:0019068=Reactome:REACT_6818, GO:0002224=Reactome:REACT_9020, GO:0046788=Reactome:REACT_115893, GO:0006281=Reactome:REACT_216, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_121374, GO:0034166=Reactome:REACT_9027, GO:0035666=Reactome:REACT_25281, GO:0000278=Reactome:REACT_152, GO:0044267=Reactome:REACT_17015, GO:0010008=Reactome:REACT_115855, GO:0016044=Reactome:REACT_11123, GO:0034162=Reactome:REACT_9047, GO:0050852=Reactome:REACT_12526, GO:0022415=Reactome:REACT_6361, GO:0034142=Reactome:REACT_6894, GO:0070423=Reactome:REACT_75776, GO:0015935=PMID:15883184, GO:0061418=Reactome:REACT_120815, GO:0031145=Reactome:REACT_6871, GO:0035872=Reactome:REACT_75913, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_25090, GO:0000084=Reactome:REACT_899, GO:0000187=Reactome:REACT_21399, GO:0000082=Reactome:REACT_1783, GO:0051092=Reactome:REACT_21281, GO:0000184=Reactome:REACT_75886, GO:0045944=Reactome:REACT_120734, GO:0000087=Reactome:REACT_910, GO:0016197=Reactome:REACT_27258, GO:0016032=Reactome:REACT_6256, GO:0032481=Reactome:REACT_147841, GO:0000080=Reactome:REACT_1590, GO:0032480=Reactome:REACT_25271, GO:0034138=Reactome:REACT_6783, GO:0030512=Reactome:REACT_120727, GO:0048011=Reactome:REACT_13776, GO:0043066=Reactome:REACT_13537, GO:0003735=PMID:15883184, GO:0006614=Reactome:REACT_115902, GO:0019083=Reactome:REACT_6152, GO:0019082=Reactome:REACT_115860, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0007254=Reactome:REACT_21368, GO:0071456=Reactome:REACT_121311, GO:0006915=Reactome:REACT_13643, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0006415=Reactome:REACT_1986, GO:0097190=Reactome:REACT_13720, GO:0055085=Reactome:REACT_15518, GO:0051439=Reactome:REACT_6837, GO:0006351=Reactome:REACT_121061, GO:0030666=Reactome:REACT_27184, GO:0022627=PMID:8706699, GO:0002479=Reactome:REACT_111178, GO:0034146=Reactome:REACT_9061, GO:0000090=Reactome:REACT_1275} P62979 Ubiquitin-40S ribosomal protein S27a protein 20100831 {GO:0002474=TAS, GO:0010467=TAS, GO:0007220=TAS, GO:0006367=TAS, GO:0019221=TAS, GO:0007249=TAS, GO:0019058=TAS, GO:0051403=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0006414=TAS, GO:0002756=TAS, GO:0034220=TAS, GO:0007219=TAS, GO:0007173=TAS, GO:0002755=TAS, GO:0007179=TAS, GO:0043123=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0038124=TAS, GO:0038123=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0034134=TAS, GO:0042059=TAS, GO:0033554=TAS, GO:0000122=TAS, GO:0019068=TAS, GO:0002224=TAS, GO:0046788=TAS, GO:0006281=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0034166=TAS, GO:0035666=TAS, GO:0000278=TAS, GO:0044267=TAS, GO:0010008=TAS, GO:0016044=TAS, GO:0034162=TAS, GO:0050852=TAS, GO:0022415=TAS, GO:0034142=TAS, GO:0070423=TAS, GO:0015935=IDA, GO:0061418=TAS, GO:0031145=TAS, GO:0035872=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0000084=TAS, GO:0000187=TAS, GO:0000082=TAS, GO:0051092=TAS, GO:0000184=TAS, GO:0045944=TAS, GO:0000087=TAS, GO:0016197=TAS, GO:0016032=TAS, GO:0032481=TAS, GO:0000080=TAS, GO:0032480=TAS, GO:0034138=TAS, GO:0030512=TAS, GO:0048011=TAS, GO:0043066=TAS, GO:0003735=IDA, GO:0006614=TAS, GO:0019083=TAS, GO:0019082=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0007254=TAS, GO:0071456=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0006415=TAS, GO:0097190=TAS, GO:0055085=TAS, GO:0051439=TAS, GO:0006351=TAS, GO:0030666=TAS, GO:0022627=IDA, GO:0002479=TAS, GO:0034146=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, DNA repair, G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, I-kappaB kinase/NF-kappaB cascade, JNK cascade, M phase of mitotic cell cycle, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, Notch receptor processing, Notch signaling pathway, RNA metabolic process, S phase of mitotic cell cycle, SRP-dependent cotranslational protein targeting to membrane, T cell receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, activation of MAPK activity, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, apoptotic signaling pathway, cell cycle checkpoint, cellular membrane organization, cellular protein metabolic process, cellular response to hypoxia, cellular response to stress, cytokine-mediated signaling pathway, egress of virus within host cell, endosomal transport, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, gene expression, innate immune response, ion transmembrane transport, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of apoptotic process, negative regulation of epidermal growth factor receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transforming growth factor beta receptor signaling pathway, negative regulation of type I interferon production, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, neurotrophin TRK receptor signaling pathway, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, nucleotide-binding oligomerization domain containing signaling pathway, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, positive regulation of type I interferon production, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, regulation of apoptotic process, regulation of transcription from RNA polymerase II promoter in response to hypoxia, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, translation, translational elongation, translational initiation, translational termination, transmembrane transport, viral infectious cycle, viral protein processing, viral reproduction, viral reproductive process, viral transcription, virion assembly cytosol, cytosolic small ribosomal subunit, endocytic vesicle membrane, endosome membrane, nucleoplasm, small ribosomal subunit metal ion binding, structural constituent of ribosome Human RPS27L GOC UniProtKB {GO:0005515=PMID:21170087, GO:0003735=GO_REF:0000002, GO:0006919=PMID:17057733, GO:0045727=PMID:18056458, GO:0005634=PMID:18056458, GO:0008494=PMID:18056458, GO:0006412=PMID:18056458, GO:0008656=PMID:17057733, GO:0046872=GO_REF:0000037, GO:0006974=PMID:18056458, GO:0042771=PMID:17057733, GO:0006281=PMID:18056458, GO:0005840=GO_REF:0000037, GO:0031571=PMID:18056458} Q71UM5 40S ribosomal protein S27-like protein 20130413 {GO:0005515=IPI, GO:0003735=IEA, GO:0006919=IDA, GO:0045727=IDA, GO:0005634=IDA, GO:0008494=IDA, GO:0006412=IDA, GO:0008656=IDA, GO:0046872=IEA, GO:0006974=IDA, GO:0042771=IDA, GO:0006281=IMP, GO:0005840=IEA, GO:0031571=IMP} DNA repair, activation of cysteine-type endopeptidase activity involved in apoptotic process, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, mitotic G1 DNA damage checkpoint, positive regulation of translation, response to DNA damage stimulus, translation nucleus, ribosome cysteine-type endopeptidase activator activity involved in apoptotic process, metal ion binding, protein binding, structural constituent of ribosome, translation activator activity Human RPS28 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=GO_REF:0000002, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006364=PMID:18697920, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0015935=PMID:15883184, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0022627=PMID:8706699, GO:0016032=Reactome:REACT_6145, GO:0042274=PMID:18697920, GO:0044267=Reactome:REACT_17015} P62857 40S ribosomal protein S28 protein 20130213 {GO:0010467=TAS, GO:0003735=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006364=IMP, GO:0006614=TAS, GO:0019058=TAS, GO:0015935=IDA, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0022627=IDA, GO:0016032=TAS, GO:0042274=IMP, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, rRNA processing, ribosomal small subunit biogenesis, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic small ribosomal subunit, small ribosomal subunit structural constituent of ribosome Human RPS29 HPA UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:15883184, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0015935=PMID:15883184, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0005737=GO_REF:0000052, GO:0000184=Reactome:REACT_75886, GO:0022627=PMID:8706699, GO:0016032=Reactome:REACT_6145, GO:0008270=PMID:8781548, GO:0044267=Reactome:REACT_17015} P62273 40S ribosomal protein S29 protein 20080205 {GO:0010467=TAS, GO:0003735=IDA, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0015935=IDA, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0005737=IDA, GO:0000184=TAS, GO:0022627=IDA, GO:0016032=TAS, GO:0008270=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytoplasm, cytosol, cytosolic small ribosomal subunit, small ribosomal subunit structural constituent of ribosome, zinc ion binding Human RPS3 IntAct UniProtKB {GO:0003906=PMID:16737853, GO:0005515=PMID:21399639, GO:0010467=Reactome:REACT_71, GO:0003723=GO_REF:0000002, GO:0019058=Reactome:REACT_6167, GO:0045738=PMID:17049931, GO:0015935=GO_REF:0000002, GO:0005634=PMID:18045535, GO:0003729=PMID:18464793, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0006414=Reactome:REACT_1477, GO:0005829=Reactome:REACT_115921, GO:0005737=PMID:14988002, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0051018=PMID:16814409, GO:0003735=PMID:1712897, GO:0016070=Reactome:REACT_21257, GO:0019901=PMID:15950189, GO:0051536=PMID:11911468, GO:0051059=PMID:18045535, GO:0016071=Reactome:REACT_20605, GO:0006919=PMID:14988002, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0032587=PMID:16814409, GO:0032088=PMID:18045535, GO:0006917=PMID:14988002, GO:0006415=Reactome:REACT_1986, GO:0006974=PMID:17560175, GO:0003684=PMID:16737853, GO:0004519=PMID:16584637, GO:0022627=PMID:8706699, GO:0030529=PMID:17289661, GO:0005840=GO_REF:0000038, GO:0044267=Reactome:REACT_17015} P23396 40S ribosomal protein S3 protein 20130415 {GO:0003906=IDA, GO:0005515=IPI, GO:0010467=TAS, GO:0003723=IEA, GO:0019058=TAS, GO:0045738=IMP, GO:0015935=IEA, GO:0005634=IDA, GO:0003729=IDA, GO:0006412=TAS, GO:0006413=TAS, GO:0006414=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0000184=TAS, GO:0016032=TAS, GO:0051018=IPI, GO:0003735=NAS, GO:0016070=TAS, GO:0019901=IPI, GO:0051536=NAS, GO:0051059=IPI, GO:0016071=TAS, GO:0006919=IDA, GO:0019083=TAS, GO:0006614=TAS, GO:0032587=IDA, GO:0032088=IMP, GO:0006917=IDA, GO:0006415=TAS, GO:0006974=IEP, GO:0003684=IDA, GO:0004519=IMP, GO:0022627=IDA, GO:0030529=IDA, GO:0005840=IEA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, activation of cysteine-type endopeptidase activity involved in apoptotic process, cellular protein metabolic process, gene expression, induction of apoptosis, mRNA metabolic process, negative regulation of DNA repair, negative regulation of NF-kappaB transcription factor activity, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, response to DNA damage stimulus, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytoplasm, cytosol, cytosolic small ribosomal subunit, nucleus, ribonucleoprotein complex, ribosome, ruffle membrane, small ribosomal subunit DNA-(apurinic or apyrimidinic site) lyase activity, NF-kappaB binding, RNA binding, damaged DNA binding, endonuclease activity, iron-sulfur cluster binding, mRNA binding, protein binding, protein kinase A binding, protein kinase binding, structural constituent of ribosome Human UniProtKB:O14920 RPS3A IntAct UniProtKB {GO:0005515=PMID:16169070, GO:0010467=Reactome:REACT_71, GO:0003723=PMID:1398113, GO:0019058=Reactome:REACT_6167, GO:0005634=GO_REF:0000024, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0030154=GO_REF:0000037, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0005737=PMID:11823430, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0003735=GO_REF:0000002, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006614=Reactome:REACT_115902, GO:0019083=Reactome:REACT_6152, GO:0005730=PMID:15572026, GO:0006917=PMID:9566973, GO:0006415=Reactome:REACT_1986, GO:0022627=PMID:8706699, GO:0030529=PMID:18809582, GO:0005840=GO_REF:0000002, GO:0044267=Reactome:REACT_17015} P61247 40S ribosomal protein S3a protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0003723=NAS, GO:0019058=TAS, GO:0005634=ISS, GO:0006412=TAS, GO:0006413=TAS, GO:0030154=IEA, GO:0005829=TAS, GO:0006414=TAS, GO:0005737=IDA, GO:0000184=TAS, GO:0016032=TAS, GO:0003735=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0006614=TAS, GO:0019083=TAS, GO:0005730=IDA, GO:0006917=IMP, GO:0006415=TAS, GO:0022627=IDA, GO:0030529=IDA, GO:0005840=IEA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cell differentiation, cellular protein metabolic process, gene expression, induction of apoptosis, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytoplasm, cytosol, cytosolic small ribosomal subunit, nucleolus, nucleus, ribonucleoprotein complex, ribosome RNA binding, protein binding, structural constituent of ribosome Human UniProtKB:P07900 RPS4X Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0008284=PMID:1795030, GO:0003723=GO_REF:0000002, GO:0015935=PMID:8139551, GO:0019058=Reactome:REACT_6167, GO:0019843=GO_REF:0000037, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0003735=PMID:8358435, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006614=Reactome:REACT_115902, GO:0019083=Reactome:REACT_6152, GO:0007275=PMID:8358435, GO:0045727=PMID:1795030, GO:0006415=Reactome:REACT_1986, GO:0022627=PMID:2124517, GO:0030529=PMID:17289661, GO:0005840=PMID:15883184, GO:0005844=PMID:8139551, GO:0044267=Reactome:REACT_17015} P62701 40S ribosomal protein S4, X isoform protein 20130213 {GO:0010467=TAS, GO:0008284=IMP, GO:0003723=IEA, GO:0015935=IDA, GO:0019058=TAS, GO:0019843=IEA, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0016032=TAS, GO:0003735=IMP, GO:0016070=TAS, GO:0016071=TAS, GO:0006614=TAS, GO:0019083=TAS, GO:0007275=IMP, GO:0045727=IMP, GO:0006415=TAS, GO:0022627=NAS, GO:0030529=IDA, GO:0005840=IDA, GO:0005844=IDA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, multicellular organismal development, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, positive regulation of cell proliferation, positive regulation of translation, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic small ribosomal subunit, polysome, ribonucleoprotein complex, ribosome, small ribosomal subunit RNA binding, rRNA binding, structural constituent of ribosome Human RPS4Y1 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:8358435, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0003723=PMID:2124517, GO:0019058=Reactome:REACT_6167, GO:0007275=PMID:8358435, GO:0019843=GO_REF:0000037, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0022627=PMID:8358435, GO:0016032=Reactome:REACT_6145, GO:0005840=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0005844=PMID:8139551} P22090 40S ribosomal protein S4, Y isoform 1 protein 20130213 {GO:0010467=TAS, GO:0003735=IMP, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0003723=TAS, GO:0019058=TAS, GO:0007275=IMP, GO:0019843=IEA, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0022627=NAS, GO:0016032=TAS, GO:0005840=IEA, GO:0044267=TAS, GO:0005844=IDA} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, multicellular organismal development, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic small ribosomal subunit, polysome, ribosome RNA binding, rRNA binding, structural constituent of ribosome Human RPS4Y2 UniProtKB UniProtKB {GO:0003735=GO_REF:0000002, GO:0005840=GO_REF:0000037, GO:0019843=GO_REF:0000037, GO:0006412=GO_REF:0000002} Q8TD47 40S ribosomal protein S4, Y isoform 2 protein 20130413 {GO:0003735=IEA, GO:0005840=IEA, GO:0019843=IEA, GO:0006412=IEA} translation ribosome rRNA binding, structural constituent of ribosome Human UniProtKB-KW:KW-0699 RPS5 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003735=PMID:15883184, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0003723=PMID:7772601, GO:0019058=Reactome:REACT_6167, GO:0015935=GO_REF:0000002, GO:0003729=PMID:18464793, GO:0006415=Reactome:REACT_1986, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0022627=PMID:8706699, GO:0030529=PMID:18809582, GO:0016032=Reactome:REACT_6145, GO:0006450=PMID:17901157, GO:0044267=Reactome:REACT_17015} P46782 40S ribosomal protein S5 protein 20130213 {GO:0010467=TAS, GO:0003735=IDA, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0003723=NAS, GO:0019058=TAS, GO:0015935=IEA, GO:0003729=IDA, GO:0006415=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0022627=IDA, GO:0030529=IDA, GO:0016032=TAS, GO:0006450=IGI, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, regulation of translational fidelity, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytosol, cytosolic small ribosomal subunit, ribonucleoprotein complex, small ribosomal subunit RNA binding, mRNA binding, structural constituent of ribosome Human RPS6 HPA UniProtKB {GO:0005515=PMID:18423201, GO:0008286=Reactome:REACT_498, GO:0010467=Reactome:REACT_71, GO:0006364=PMID:18697920, GO:0019058=Reactome:REACT_6167, GO:0015935=PMID:15590835, GO:0005634=PMID:2334893, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0006414=Reactome:REACT_1477, GO:0005829=Reactome:REACT_115921, GO:0005737=GO_REF:0000052, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0042274=PMID:18697920, GO:0000028=GO_REF:0000019, GO:0031929=PMID:16428328, GO:0043065=PMID:18362888, GO:0003735=GO_REF:0000002, GO:0019901=PMID:21418524, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006614=Reactome:REACT_115902, GO:0019083=Reactome:REACT_6152, GO:0005730=PMID:8590812, GO:0042593=GO_REF:0000024, GO:0006415=Reactome:REACT_1986, GO:0022627=PMID:8706699, GO:0030529=PMID:18809582, GO:0005840=GO_REF:0000002, GO:0044267=Reactome:REACT_17015} P62753 40S ribosomal protein S6 protein 20111111 {GO:0005515=IPI, GO:0008286=TAS, GO:0010467=TAS, GO:0006364=IMP, GO:0019058=TAS, GO:0015935=IDA, GO:0005634=IDA, GO:0006412=TAS, GO:0006413=TAS, GO:0006414=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0000184=TAS, GO:0016032=TAS, GO:0042274=IMP, GO:0000028=IEA, GO:0031929=IDA, GO:0043065=IDA, GO:0003735=IEA, GO:0019901=IPI, GO:0016070=TAS, GO:0016071=TAS, GO:0006614=TAS, GO:0019083=TAS, GO:0005730=IDA, GO:0042593=ISS, GO:0006415=TAS, GO:0022627=IDA, GO:0030529=IDA, GO:0005840=IEA, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, TOR signaling cascade, cellular protein metabolic process, gene expression, glucose homeostasis, insulin receptor signaling pathway, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, positive regulation of apoptotic process, rRNA processing, ribosomal small subunit assembly, ribosomal small subunit biogenesis, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytoplasm, cytosol, cytosolic small ribosomal subunit, nucleolus, nucleus, ribonucleoprotein complex, ribosome, small ribosomal subunit protein binding, protein kinase binding, structural constituent of ribosome Human RPS6KA1 HPA UniProtKB {GO:0005515=PMID:23455922, GO:0034142=Reactome:REACT_6894, GO:2000491=PMID:10679322, GO:0030307=PMID:18813292, GO:0045597=PMID:18813292, GO:0007268=Reactome:REACT_13685, GO:0005634=GO_REF:0000052, GO:0043620=PMID:18813292, GO:0051403=Reactome:REACT_21308, GO:0007243=GO_REF:0000002, GO:0005829=Reactome:REACT_20562, GO:0043555=PMID:18813292, GO:0002756=Reactome:REACT_6809, GO:0005737=GO_REF:0000052, GO:0007411=Reactome:REACT_18266, GO:0045944=PMID:22065586, GO:0002755=Reactome:REACT_27215, GO:0043154=PMID:18402937, GO:0034138=Reactome:REACT_6783, GO:0043027=PMID:18402937, GO:0048011=Reactome:REACT_11061, GO:0043066=PMID:11684016, GO:0038124=Reactome:REACT_8006, GO:0000287=GO_REF:0000002, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0005819=GO_REF:0000019, GO:0002224=Reactome:REACT_9020, GO:0005524=GO_REF:0000002, GO:0007165=PMID:8141249, GO:0007049=GO_REF:0000037, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000002, GO:0045087=Reactome:REACT_6802, GO:0035666=Reactome:REACT_25281, GO:0034166=Reactome:REACT_9027, GO:0005654=Reactome:REACT_20640, GO:0034146=Reactome:REACT_9061, GO:0034162=Reactome:REACT_9047} Q5SVM7 Ribosomal protein S6 kinase alpha-1 protein 20080205 {GO:0005515=IPI, GO:0034142=TAS, GO:2000491=IMP, GO:0030307=TAS, GO:0045597=TAS, GO:0007268=TAS, GO:0005634=IDA, GO:0043620=TAS, GO:0051403=TAS, GO:0007243=IEA, GO:0005829=TAS, GO:0043555=TAS, GO:0002756=TAS, GO:0005737=IDA, GO:0007411=TAS, GO:0045944=IMP, GO:0002755=TAS, GO:0043154=IDA, GO:0034138=TAS, GO:0043027=IDA, GO:0048011=TAS, GO:0043066=IMP, GO:0038124=TAS, GO:0000287=IEA, GO:0038123=TAS, GO:0034134=TAS, GO:0005819=IEA, GO:0002224=TAS, GO:0005524=IEA, GO:0007165=TAS, GO:0007049=IEA, GO:0004672=IEA, GO:0004674=IEA, GO:0045087=TAS, GO:0035666=TAS, GO:0034166=TAS, GO:0005654=TAS, GO:0034146=TAS, GO:0034162=TAS} MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, axon guidance, cell cycle, innate immune response, intracellular protein kinase cascade, negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, neurotrophin TRK receptor signaling pathway, positive regulation of cell differentiation, positive regulation of cell growth, positive regulation of hepatic stellate cell activation, positive regulation of transcription from RNA polymerase II promoter, regulation of DNA-dependent transcription in response to stress, regulation of translation in response to stress, signal transduction, stress-activated MAPK cascade, synaptic transmission, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway cytoplasm, cytosol, nucleoplasm, nucleus, spindle ATP binding, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, magnesium ion binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human RPS6KA2 InterPro UniProtKB {GO:0060047=GO_REF:0000019, GO:0034142=Reactome:REACT_6894, GO:0008285=PMID:16878154, GO:0070613=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0005634=PMID:16878154, GO:0001556=GO_REF:0000019, GO:0051403=Reactome:REACT_21308, GO:0007243=PMID:8141249, GO:0005829=Reactome:REACT_20562, GO:0007507=GO_REF:0000019, GO:0035556=PMID:7623830, GO:0002756=Reactome:REACT_6809, GO:0005737=PMID:16878154, GO:0018105=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0000089=GO_REF:0000019, GO:0002755=Reactome:REACT_27215, GO:0034138=Reactome:REACT_6783, GO:0048011=Reactome:REACT_11061, GO:0038124=Reactome:REACT_8006, GO:0000287=GO_REF:0000002, GO:0043065=PMID:16878154, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0005819=GO_REF:0000019, GO:0002035=GO_REF:0000019, GO:0002224=Reactome:REACT_9020, GO:0045786=PMID:16878154, GO:0005524=GO_REF:0000002, GO:0010628=GO_REF:0000019, GO:0007165=PMID:7623830, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000002, GO:0045087=Reactome:REACT_6802, GO:0010659=GO_REF:0000019, GO:0004711=GO_REF:0000019, GO:0005840=GO_REF:0000038, GO:0035666=Reactome:REACT_25281, GO:0034166=Reactome:REACT_9027, GO:0005654=Reactome:REACT_20640, GO:0034146=Reactome:REACT_9061, GO:0034162=Reactome:REACT_9047, GO:0071322=GO_REF:0000019} Q5TI62 Ribosomal protein S6 kinase alpha-2 protein 20130413 {GO:0060047=IEA, GO:0034142=TAS, GO:0008285=IDA, GO:0070613=IEA, GO:0007268=TAS, GO:0005634=IDA, GO:0001556=IEA, GO:0051403=TAS, GO:0007243=TAS, GO:0005829=TAS, GO:0007507=IEA, GO:0035556=TAS, GO:0002756=TAS, GO:0005737=IDA, GO:0018105=IEA, GO:0007411=TAS, GO:0000089=IEA, GO:0002755=TAS, GO:0034138=TAS, GO:0048011=TAS, GO:0038124=TAS, GO:0000287=IEA, GO:0043065=IDA, GO:0038123=TAS, GO:0034134=TAS, GO:0005819=IEA, GO:0002035=IEA, GO:0002224=TAS, GO:0045786=IDA, GO:0005524=IEA, GO:0010628=IEA, GO:0007165=NAS, GO:0004672=IEA, GO:0004674=IEA, GO:0045087=TAS, GO:0010659=IEA, GO:0004711=IEA, GO:0005840=IEA, GO:0035666=TAS, GO:0034166=TAS, GO:0005654=TAS, GO:0034146=TAS, GO:0034162=TAS, GO:0071322=IEA} MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, axon guidance, brain renin-angiotensin system, cardiac muscle cell apoptotic process, cellular response to carbohydrate stimulus, heart contraction, heart development, innate immune response, intracellular protein kinase cascade, intracellular signal transduction, mitotic metaphase, negative regulation of cell cycle, negative regulation of cell proliferation, neurotrophin TRK receptor signaling pathway, oocyte maturation, peptidyl-serine phosphorylation, positive regulation of apoptotic process, positive regulation of gene expression, regulation of protein processing, signal transduction, stress-activated MAPK cascade, synaptic transmission, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway cytoplasm, cytosol, nucleoplasm, nucleus, ribosome, spindle ATP binding, magnesium ion binding, protein kinase activity, protein serine/threonine kinase activity, ribosomal protein S6 kinase activity Human InterPro:IPR000719 RPS6KA3 BHF-UCL UniProtKB {GO:0034142=Reactome:REACT_6894, GO:0030307=PMID:18813292, GO:0045597=PMID:18813292, GO:0007268=Reactome:REACT_13685, GO:0043620=PMID:18813292, GO:0051403=Reactome:REACT_21308, GO:0007243=GO_REF:0000002, GO:0005829=Reactome:REACT_20562, GO:0002756=Reactome:REACT_6809, GO:0043555=PMID:18813292, GO:0007411=Reactome:REACT_18266, GO:0045944=PMID:22065586, GO:0002755=Reactome:REACT_27215, GO:0032496=GO_REF:0000024, GO:0043154=PMID:18402937, GO:0034138=Reactome:REACT_6783, GO:0043027=PMID:18402937, GO:0048011=Reactome:REACT_11061, GO:0043066=PMID:18813292, GO:0038124=Reactome:REACT_8006, GO:0000287=GO_REF:0000002, GO:0038123=Reactome:REACT_8005, GO:0019901=GO_REF:0000019, GO:0034134=Reactome:REACT_7980, GO:0002224=Reactome:REACT_9020, GO:0007417=PMID:10319851, GO:0005524=GO_REF:0000037, GO:0007165=PMID:10436156, GO:0007049=GO_REF:0000037, GO:0001501=PMID:8955270, GO:0004672=PMID:10436156, GO:0004674=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0005840=GO_REF:0000038, GO:0035666=Reactome:REACT_25281, GO:0034166=Reactome:REACT_9027, GO:0005654=Reactome:REACT_20640, GO:0034146=Reactome:REACT_9061, GO:0034162=Reactome:REACT_9047} P51812 Ribosomal protein S6 kinase alpha-3 protein 20111212 {GO:0034142=TAS, GO:0030307=TAS, GO:0045597=TAS, GO:0007268=TAS, GO:0043620=TAS, GO:0051403=TAS, GO:0007243=IEA, GO:0005829=TAS, GO:0002756=TAS, GO:0043555=TAS, GO:0007411=TAS, GO:0045944=IMP, GO:0002755=TAS, GO:0032496=ISS, GO:0043154=IDA, GO:0034138=TAS, GO:0043027=IDA, GO:0048011=TAS, GO:0043066=TAS, GO:0038124=TAS, GO:0000287=IEA, GO:0038123=TAS, GO:0019901=IEA, GO:0034134=TAS, GO:0002224=TAS, GO:0007417=TAS, GO:0005524=IEA, GO:0007165=TAS, GO:0007049=IEA, GO:0001501=TAS, GO:0004672=TAS, GO:0004674=IEA, GO:0045087=TAS, GO:0005840=IEA, GO:0035666=TAS, GO:0034166=TAS, GO:0005654=TAS, GO:0034146=TAS, GO:0034162=TAS} MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, axon guidance, cell cycle, central nervous system development, innate immune response, intracellular protein kinase cascade, negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, neurotrophin TRK receptor signaling pathway, positive regulation of cell differentiation, positive regulation of cell growth, positive regulation of transcription from RNA polymerase II promoter, regulation of DNA-dependent transcription in response to stress, regulation of translation in response to stress, response to lipopolysaccharide, signal transduction, skeletal system development, stress-activated MAPK cascade, synaptic transmission, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway cytosol, nucleoplasm, ribosome ATP binding, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, magnesium ion binding, protein kinase activity, protein kinase binding, protein serine/threonine kinase activity Human RPS6KA4 HPA UniProtKB {GO:0005515=PMID:9792677, GO:0005634=GO_REF:0000052, GO:0001818=PMID:18508628, GO:0035066=PMID:20018936, GO:0007243=PMID:9792677, GO:0005737=GO_REF:0000052, GO:0006954=GO_REF:0000037, GO:0051092=PMID:18508628, GO:0007411=Reactome:REACT_18266, GO:0045944=PMID:20018936, GO:0048273=PMID:11035004, GO:0070498=PMID:20018936, GO:0006355=PMID:9792677, GO:0000287=GO_REF:0000002, GO:0016572=PMID:20018936, GO:0005730=GO_REF:0000052, GO:0005524=PMID:9792677, GO:0032793=PMID:18508628, GO:0033129=PMID:20018936, GO:0004674=PMID:12773393, GO:0043987=PMID:12773393, GO:0043988=PMID:12773393, GO:0004711=PMID:11035004, GO:0005840=GO_REF:0000038, GO:0006468=PMID:9792677} O75676 Ribosomal protein S6 kinase alpha-4 protein 20101115 {GO:0005515=IPI, GO:0005634=IDA, GO:0001818=TAS, GO:0035066=IMP, GO:0007243=IDA, GO:0005737=IDA, GO:0006954=IEA, GO:0051092=TAS, GO:0007411=TAS, GO:0045944=IMP, GO:0048273=IGI, GO:0070498=IMP, GO:0006355=IDA, GO:0000287=IEA, GO:0016572=TAS, GO:0005730=IDA, GO:0005524=IDA, GO:0032793=TAS, GO:0033129=IMP, GO:0004674=IMP, GO:0043987=IMP, GO:0043988=IMP, GO:0004711=NAS, GO:0005840=IEA, GO:0006468=IDA} axon guidance, histone H3-S10 phosphorylation, histone H3-S28 phosphorylation, histone phosphorylation, inflammatory response, interleukin-1-mediated signaling pathway, intracellular protein kinase cascade, negative regulation of cytokine production, positive regulation of CREB transcription factor activity, positive regulation of NF-kappaB transcription factor activity, positive regulation of histone acetylation, positive regulation of histone phosphorylation, positive regulation of transcription from RNA polymerase II promoter, protein phosphorylation, regulation of transcription, DNA-dependent cytoplasm, nucleolus, nucleus, ribosome ATP binding, magnesium ion binding, mitogen-activated protein kinase p38 binding, protein binding, protein serine/threonine kinase activity, ribosomal protein S6 kinase activity Human RPS6KA5 BHF-UCL UniProtKB {GO:0005515=PMID:21988832, GO:0034142=Reactome:REACT_6894, GO:0005634=PMID:18511904, GO:0001818=PMID:18508628, GO:0035066=PMID:20018936, GO:0051403=Reactome:REACT_21308, GO:0007243=PMID:9687510, GO:0002756=Reactome:REACT_6809, GO:0005737=PMID:18511904, GO:0051092=PMID:18511904, GO:0006954=GO_REF:0000037, GO:0007173=PMID:9873047, GO:0007411=Reactome:REACT_18266, GO:0045944=PMID:20018936, GO:0002755=Reactome:REACT_27215, GO:0034138=Reactome:REACT_6783, GO:0070498=PMID:20018936, GO:0048011=Reactome:REACT_11061, GO:0006355=PMID:12763138, GO:0038124=Reactome:REACT_8006, GO:0000287=GO_REF:0000002, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0016572=PMID:20018936, GO:0006950=PMID:9873047, GO:0002224=Reactome:REACT_9020, GO:0005524=PMID:9687510, GO:0043990=PMID:15010469, GO:0032793=PMID:18508628, GO:0033129=PMID:20018936, GO:0009605=PMID:9873047, GO:0004672=PMID:9873047, GO:0004674=PMID:12773393, GO:0045087=Reactome:REACT_6802, GO:0043987=PMID:12773393, GO:0005840=GO_REF:0000038, GO:0043988=PMID:12773393, GO:0035666=Reactome:REACT_25281, GO:0034166=Reactome:REACT_9027, GO:0006468=PMID:9687510, GO:0005654=Reactome:REACT_12631, GO:0034146=Reactome:REACT_9061, GO:0045892=PMID:15010469, GO:0034162=Reactome:REACT_9047} O75582 Ribosomal protein S6 kinase alpha-5 protein 20110427 {GO:0005515=IPI, GO:0034142=TAS, GO:0005634=IDA, GO:0001818=TAS, GO:0035066=IMP, GO:0051403=TAS, GO:0007243=IDA, GO:0002756=TAS, GO:0005737=IDA, GO:0051092=IMP, GO:0006954=IEA, GO:0007173=TAS, GO:0007411=TAS, GO:0045944=IMP, GO:0002755=TAS, GO:0034138=TAS, GO:0070498=IMP, GO:0048011=TAS, GO:0006355=IMP, GO:0038124=TAS, GO:0000287=IEA, GO:0038123=TAS, GO:0034134=TAS, GO:0016572=TAS, GO:0006950=IEP, GO:0002224=TAS, GO:0005524=IDA, GO:0043990=IDA, GO:0032793=TAS, GO:0033129=IMP, GO:0009605=IEP, GO:0004672=IDA, GO:0004674=IMP, GO:0045087=TAS, GO:0043987=IMP, GO:0005840=IEA, GO:0043988=IMP, GO:0035666=TAS, GO:0034166=TAS, GO:0006468=IDA, GO:0005654=TAS, GO:0034146=TAS, GO:0045892=IDA, GO:0034162=TAS} MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, axon guidance, epidermal growth factor receptor signaling pathway, histone H2A-S1 phosphorylation, histone H3-S10 phosphorylation, histone H3-S28 phosphorylation, histone phosphorylation, inflammatory response, innate immune response, interleukin-1-mediated signaling pathway, intracellular protein kinase cascade, negative regulation of cytokine production, negative regulation of transcription, DNA-dependent, neurotrophin TRK receptor signaling pathway, positive regulation of CREB transcription factor activity, positive regulation of NF-kappaB transcription factor activity, positive regulation of histone acetylation, positive regulation of histone phosphorylation, positive regulation of transcription from RNA polymerase II promoter, protein phosphorylation, regulation of transcription, DNA-dependent, response to external stimulus, response to stress, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway cytoplasm, nucleoplasm, nucleus, ribosome ATP binding, magnesium ion binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human RPS6KA6 Reactome UniProtKB {GO:0000287=GO_REF:0000002, GO:2000381=GO_REF:0000024, GO:0007268=Reactome:REACT_13685, GO:0007417=PMID:10644430, GO:0005524=GO_REF:0000037, GO:0007243=GO_REF:0000002, GO:0045992=GO_REF:0000024, GO:0005829=Reactome:REACT_20562, GO:0007165=PMID:10644430, GO:0004672=PMID:10644430, GO:0007411=Reactome:REACT_18266, GO:0004674=GO_REF:0000037, GO:0070373=GO_REF:0000024, GO:0005654=Reactome:REACT_20640, GO:0006978=PMID:15042092} Q9UK32 Ribosomal protein S6 kinase alpha-6 protein 20130301 {GO:0000287=IEA, GO:2000381=ISS, GO:0007268=TAS, GO:0007417=TAS, GO:0005524=IEA, GO:0007243=IEA, GO:0045992=ISS, GO:0005829=TAS, GO:0007165=TAS, GO:0004672=TAS, GO:0007411=TAS, GO:0004674=IEA, GO:0070373=ISS, GO:0005654=TAS, GO:0006978=IMP} DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, axon guidance, central nervous system development, intracellular protein kinase cascade, negative regulation of ERK1 and ERK2 cascade, negative regulation of embryonic development, negative regulation of mesoderm development, signal transduction, synaptic transmission cytosol, nucleoplasm ATP binding, magnesium ion binding, protein kinase activity, protein serine/threonine kinase activity Human RPS6KB1 UniProtKB UniProtKB {GO:0005515=PMID:22439934, GO:0030054=GO_REF:0000037, GO:0009408=GO_REF:0000019, GO:0045202=GO_REF:0000037, GO:0007281=GO_REF:0000019, GO:0046324=GO_REF:0000019, GO:0014878=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0031929=PMID:12150926, GO:0032868=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0007616=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0009636=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0045931=PMID:14673156, GO:0048633=GO_REF:0000019, GO:0043491=GO_REF:0000019, GO:0008286=Reactome:REACT_498, GO:0043005=GO_REF:0000039, GO:0048471=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0005741=GO_REF:0000039, GO:0032870=GO_REF:0000019, GO:0005829=Reactome:REACT_6948, GO:0014911=GO_REF:0000019, GO:0005739=PMID:17936702, GO:0000082=PMID:14673156, GO:0033762=GO_REF:0000019, GO:0045948=PMID:16763566, GO:0043201=GO_REF:0000019, GO:0042277=GO_REF:0000019, GO:0043066=PMID:17936702, GO:0007584=GO_REF:0000019, GO:0048015=PMID:9445476, GO:0042493=GO_REF:0000019, GO:0046627=PMID:18952604, GO:0009611=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0045727=PMID:18423201, GO:0014732=GO_REF:0000019, GO:0033574=GO_REF:0000019, GO:0005524=GO_REF:0000038, GO:0048661=GO_REF:0000019, GO:0009749=GO_REF:0000019, GO:0009612=GO_REF:0000019, GO:0007165=GO_REF:0000002, GO:0004672=PMID:18952604, GO:0071363=PMID:17936702, GO:0016477=GO_REF:0000019, GO:0003009=GO_REF:0000019, GO:0004674=GO_REF:0000038, GO:0005840=GO_REF:0000038, GO:0004711=GO_REF:0000019, GO:0034612=GO_REF:0000019} Q7Z721 Ribosomal protein S6 kinase beta-1 protein 20130413 {GO:0005515=IPI, GO:0030054=IEA, GO:0009408=IEA, GO:0045202=IEA, GO:0007281=IEA, GO:0046324=IEA, GO:0014878=IEA, GO:0032496=IEA, GO:0031929=IDA, GO:0032868=IEA, GO:0009986=IEA, GO:0007616=IEA, GO:0007568=IEA, GO:0009636=IEA, GO:0051384=IEA, GO:0045931=IMP, GO:0048633=IEA, GO:0043491=IEA, GO:0008286=TAS, GO:0043005=IEA, GO:0048471=IEA, GO:0045471=IEA, GO:0005634=IEA, GO:0005741=IEA, GO:0032870=IEA, GO:0005829=TAS, GO:0014911=IEA, GO:0005739=IDA, GO:0000082=IMP, GO:0033762=IEA, GO:0045948=IMP, GO:0043201=IEA, GO:0042277=IEA, GO:0043066=IMP, GO:0007584=IEA, GO:0048015=TAS, GO:0042493=IEA, GO:0046627=IMP, GO:0009611=IEA, GO:0006915=IEA, GO:0045727=IMP, GO:0014732=IEA, GO:0033574=IEA, GO:0005524=IEA, GO:0048661=IEA, GO:0009749=IEA, GO:0009612=IEA, GO:0007165=IEA, GO:0004672=IDA, GO:0071363=IDA, GO:0016477=IEA, GO:0003009=IEA, GO:0004674=IEA, GO:0005840=IEA, GO:0004711=IEA, GO:0034612=IEA} G1/S transition of mitotic cell cycle, TOR signaling cascade, aging, apoptotic process, cell migration, cellular response to growth factor stimulus, cellular response to hormone stimulus, germ cell development, insulin receptor signaling pathway, long-term memory, negative regulation of apoptotic process, negative regulation of insulin receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of mitotic cell cycle, positive regulation of skeletal muscle tissue growth, positive regulation of smooth muscle cell migration, positive regulation of smooth muscle cell proliferation, positive regulation of translation, positive regulation of translational initiation, protein kinase B signaling cascade, regulation of glucose import, response to drug, response to electrical stimulus involved in regulation of muscle adaptation, response to ethanol, response to glucagon stimulus, response to glucocorticoid stimulus, response to glucose stimulus, response to heat, response to insulin stimulus, response to leucine, response to lipopolysaccharide, response to mechanical stimulus, response to nutrient, response to testosterone stimulus, response to toxic substance, response to tumor necrosis factor, response to wounding, signal transduction, skeletal muscle atrophy, skeletal muscle contraction cell junction, cell surface, cytosol, mitochondrial outer membrane, mitochondrion, neuron projection, nucleus, perinuclear region of cytoplasm, ribosome, synapse ATP binding, peptide binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, ribosomal protein S6 kinase activity Human UniProtKB-KW:KW-0689 RPS6KB2 Reactome UniProtKB {GO:0042277=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0048015=Reactome:REACT_12464, GO:0005524=GO_REF:0000019, GO:0006412=PMID:9804755, GO:0007165=PMID:9804755, GO:0005737=GO_REF:0000039, GO:0004672=PMID:9804755, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9470, GO:0004674=PMID:9878560, GO:0045087=Reactome:REACT_6802, GO:0043491=GO_REF:0000019, GO:0005840=GO_REF:0000038, GO:0004711=GO_REF:0000019, GO:0045948=PMID:16763566, GO:0005654=Reactome:REACT_147791} Q9UBS0 Ribosomal protein S6 kinase beta-2 protein 20130301 {GO:0042277=IEA, GO:0048011=TAS, GO:0048015=TAS, GO:0005524=IEA, GO:0006412=TAS, GO:0007165=TAS, GO:0005737=IEA, GO:0004672=TAS, GO:0007173=TAS, GO:0008543=TAS, GO:0004674=TAS, GO:0045087=TAS, GO:0043491=IEA, GO:0005840=IEA, GO:0004711=IEA, GO:0045948=IMP, GO:0005654=TAS} epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of translational initiation, protein kinase B signaling cascade, signal transduction, translation cytoplasm, nucleoplasm, ribosome ATP binding, peptide binding, protein kinase activity, protein serine/threonine kinase activity, ribosomal protein S6 kinase activity Human RPS6KC1 PINC UniProtKB {GO:0005515=PMID:15750338, GO:0007165=PMID:10552933, GO:0004672=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0004674=GO_REF:0000037, GO:0005840=GO_REF:0000038, GO:0035091=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0005769=PMID:15750338} Q96S38 Ribosomal protein S6 kinase delta-1 protein 20061107 {GO:0005515=IPI, GO:0007165=TAS, GO:0004672=IEA, GO:0016020=IEA, GO:0004674=IEA, GO:0005840=IEA, GO:0035091=IEA, GO:0005524=IEA, GO:0005769=IDA} signal transduction early endosome, membrane, ribosome ATP binding, phosphatidylinositol binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human RPS6KL1 UniProtKB UniProtKB {GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000037, GO:0005840=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q9Y6S9 Ribosomal protein S6 kinase-like 1 protein 20130413 {GO:0004672=IEA, GO:0004674=IEA, GO:0005840=IEA, GO:0005524=IEA} ribosome ATP binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB-KW:KW-0689 RPS7 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0010467=Reactome:REACT_71, GO:0003723=PMID:8522193, GO:0006364=PMID:18697920, GO:0019058=Reactome:REACT_6167, GO:0005634=PMID:9687515, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0042274=PMID:18697920, GO:0003735=GO_REF:0000002, GO:0005815=GO_REF:0000039, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0032040=GO_REF:0000033, GO:0005730=PMID:11823430, GO:0006415=Reactome:REACT_1986, GO:0022627=PMID:8522193, GO:0030529=PMID:18809582, GO:0005840=PMID:15883184, GO:0044267=Reactome:REACT_17015, GO:0030686=GO_REF:0000033} P62081 40S ribosomal protein S7 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0003723=NAS, GO:0006364=IMP, GO:0019058=TAS, GO:0005634=IDA, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0000184=TAS, GO:0016032=TAS, GO:0042274=IMP, GO:0003735=IEA, GO:0005815=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0032040=IBA, GO:0005730=IDA, GO:0006415=TAS, GO:0022627=NAS, GO:0030529=IDA, GO:0005840=IDA, GO:0044267=TAS, GO:0030686=IBA} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, rRNA processing, ribosomal small subunit biogenesis, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription 90S preribosome, cytosol, cytosolic small ribosomal subunit, microtubule organizing center, nucleolus, nucleus, ribonucleoprotein complex, ribosome, small-subunit processome RNA binding, protein binding, structural constituent of ribosome Human UniProtKB:Q00987 RPS8 HPA UniProtKB {GO:0000462=GO_REF:0000033, GO:0010467=Reactome:REACT_71, GO:0003735=GO_REF:0000002, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0019058=Reactome:REACT_6167, GO:0006415=Reactome:REACT_1986, GO:0006412=GO_REF:0000002, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0005737=GO_REF:0000052, GO:0000184=Reactome:REACT_75886, GO:0022627=PMID:8706699, GO:0030529=PMID:17289661, GO:0005840=GO_REF:0000002, GO:0016032=Reactome:REACT_6145, GO:0044267=Reactome:REACT_17015} Q5JR95 40S ribosomal protein S8 protein 20101115 {GO:0000462=IBA, GO:0010467=TAS, GO:0003735=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0019058=TAS, GO:0006415=TAS, GO:0006412=IEA, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0005737=IDA, GO:0000184=TAS, GO:0022627=IDA, GO:0030529=IDA, GO:0005840=IEA, GO:0016032=TAS, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytoplasm, cytosol, cytosolic small ribosomal subunit, ribonucleoprotein complex, ribosome structural constituent of ribosome Human RPS9 GOC UniProtKB {GO:0005515=PMID:21988832, GO:0010467=Reactome:REACT_71, GO:0008284=PMID:18420587, GO:0015935=GO_REF:0000002, GO:0019058=Reactome:REACT_6167, GO:0019843=GO_REF:0000037, GO:0045182=PMID:18420587, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0005737=PMID:18420587, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0003735=GO_REF:0000002, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006614=Reactome:REACT_115902, GO:0019083=Reactome:REACT_6152, GO:0005730=PMID:18420587, GO:0006415=Reactome:REACT_1986, GO:0006417=PMID:18420587, GO:0022627=PMID:8706699, GO:0030529=PMID:17289661, GO:0005840=PMID:7772601, GO:0044267=Reactome:REACT_17015} P46781 40S ribosomal protein S9 protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0008284=IMP, GO:0015935=IEA, GO:0019058=TAS, GO:0019843=IEA, GO:0045182=IMP, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0005737=IDA, GO:0000184=TAS, GO:0016032=TAS, GO:0003735=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0006614=TAS, GO:0019083=TAS, GO:0005730=IDA, GO:0006415=TAS, GO:0006417=IMP, GO:0022627=IDA, GO:0030529=IDA, GO:0005840=NAS, GO:0044267=TAS} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, positive regulation of cell proliferation, regulation of translation, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription cytoplasm, cytosol, cytosolic small ribosomal subunit, nucleolus, ribonucleoprotein complex, ribosome, small ribosomal subunit protein binding, rRNA binding, structural constituent of ribosome, translation regulator activity Human RPSA Reactome UniProtKB {GO:0005515=PMID:16263087, GO:0010467=Reactome:REACT_71, GO:0000461=GO_REF:0000033, GO:0005886=PMID:16263087, GO:0019058=Reactome:REACT_6167, GO:0015935=GO_REF:0000002, GO:0005634=PMID:16130169, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0005829=Reactome:REACT_115921, GO:0006414=Reactome:REACT_1477, GO:0005737=PMID:16263087, GO:0006407=GO_REF:0000033, GO:0000184=Reactome:REACT_75886, GO:0016032=Reactome:REACT_6145, GO:0007155=PMID:2970671, GO:0000028=GO_REF:0000033, GO:0003735=GO_REF:0000033, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019083=Reactome:REACT_6152, GO:0006614=Reactome:REACT_115902, GO:0006415=Reactome:REACT_1986, GO:0022627=PMID:8706699, GO:0043022=PMID:10079194, GO:0005055=GO_REF:0000002, GO:0000447=GO_REF:0000033, GO:0044267=Reactome:REACT_17015, GO:0030686=GO_REF:0000033} P08865 40S ribosomal protein SA protein 20130213 {GO:0005515=IPI, GO:0010467=TAS, GO:0000461=IBA, GO:0005886=IDA, GO:0019058=TAS, GO:0015935=IEA, GO:0005634=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0005829=TAS, GO:0006414=TAS, GO:0005737=IDA, GO:0006407=IBA, GO:0000184=TAS, GO:0016032=TAS, GO:0007155=NAS, GO:0000028=IBA, GO:0003735=IBA, GO:0016070=TAS, GO:0016071=TAS, GO:0019083=TAS, GO:0006614=TAS, GO:0006415=TAS, GO:0022627=IDA, GO:0043022=IPI, GO:0005055=IEA, GO:0000447=IBA, GO:0044267=TAS, GO:0030686=IBA} RNA metabolic process, SRP-dependent cotranslational protein targeting to membrane, cell adhesion, cellular protein metabolic process, endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA), gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, rRNA export from nucleus, ribosomal small subunit assembly, translation, translational elongation, translational initiation, translational termination, viral infectious cycle, viral reproduction, viral transcription 90S preribosome, cytoplasm, cytosol, cytosolic small ribosomal subunit, nucleus, plasma membrane, small ribosomal subunit laminin receptor activity, protein binding, ribosome binding, structural constituent of ribosome Human RPTN UniProtKB UniProtKB {GO:0005509=GO_REF:0000002, GO:0005578=GO_REF:0000039, GO:0001533=GO_REF:0000019} Q6XPR3 Repetin protein 20130413 {GO:0005509=IEA, GO:0005578=IEA, GO:0001533=IEA} cornified envelope, proteinaceous extracellular matrix calcium ion binding Human UniProtKB-SubCell:SL-0111 RPTOR IntAct UniProtKB {GO:0008286=Reactome:REACT_498, GO:0001156=PMID:20543138, GO:0031929=PMID:20381137, GO:0005515=PMID:22424946, GO:0008361=PMID:12150925, GO:0032008=PMID:18439900, GO:0019901=PMID:18439900, GO:0071902=PMID:12150926, GO:0032403=PMID:19211835, GO:0005764=PMID:20381137, GO:0005829=Reactome:REACT_21413, GO:0071889=PMID:18439900, GO:0005737=PMID:20381137, GO:0031931=PMID:15467718, GO:0071230=PMID:20381137, GO:0045945=PMID:20233713, GO:0031669=PMID:12150925, GO:0016049=PMID:20381137, GO:0007050=Reactome:REACT_21387, GO:0001032=PMID:20233713, GO:0001030=PMID:20233713, GO:0001031=PMID:20233713} Q8N122 Regulatory-associated protein of mTOR protein 20130415 {GO:0008286=TAS, GO:0001156=IDA, GO:0031929=IDA, GO:0005515=IPI, GO:0008361=IMP, GO:0032008=IDA, GO:0019901=IPI, GO:0071902=IDA, GO:0032403=IPI, GO:0005764=IDA, GO:0005829=TAS, GO:0071889=IDA, GO:0005737=IDA, GO:0031931=IDA, GO:0071230=IMP, GO:0045945=IMP, GO:0031669=IMP, GO:0016049=IMP, GO:0007050=TAS, GO:0001032=IDA, GO:0001030=IDA, GO:0001031=IDA} TOR signaling cascade, cell cycle arrest, cell growth, cellular response to amino acid stimulus, cellular response to nutrient levels, insulin receptor signaling pathway, positive regulation of TOR signaling cascade, positive regulation of protein serine/threonine kinase activity, positive regulation of transcription from RNA polymerase III promoter, regulation of cell size TORC1 complex, cytoplasm, cytosol, lysosome 14-3-3 protein binding, RNA polymerase III type 1 promoter DNA binding, RNA polymerase III type 2 promoter DNA binding, RNA polymerase III type 3 promoter DNA binding, TFIIIC-class transcription factor binding, protein binding, protein complex binding, protein kinase binding Human UniProtKB:Q9P2J5 RPUSD1 UniProtKB UniProtKB {GO:0009982=GO_REF:0000002, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0003723=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0001522=GO_REF:0000002} Q9UJJ7 RNA pseudouridylate synthase domain-containing protein 1 protein 20091130 {GO:0009982=IEA, GO:0008150=ND, GO:0003674=ND, GO:0003723=IEA, GO:0005575=ND, GO:0001522=IEA} biological_process, pseudouridine synthesis cellular_component RNA binding, molecular_function, pseudouridine synthase activity Human RPUSD2 UniProtKB UniProtKB {GO:0009982=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0003723=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0001522=GO_REF:0000002} Q8IZ73 RNA pseudouridylate synthase domain-containing protein 2 protein 20091130 {GO:0009982=IEA, GO:0003674=ND, GO:0008150=ND, GO:0003723=IEA, GO:0005575=ND, GO:0001522=IEA} biological_process, pseudouridine synthesis cellular_component RNA binding, molecular_function, pseudouridine synthase activity Human RPUSD3 InterPro UniProtKB {GO:0009982=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0001522=GO_REF:0000002} Q6P087 RNA pseudouridylate synthase domain-containing protein 3 protein 20130413 {GO:0009982=IEA, GO:0003723=IEA, GO:0001522=IEA} pseudouridine synthesis RNA binding, pseudouridine synthase activity Human InterPro:IPR006145|InterPro:IPR020103 RPUSD4 UniProtKB UniProtKB {GO:0005515=PMID:17577209, GO:0005739=GO_REF:0000019, GO:0009982=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0001522=GO_REF:0000002} Q96CM3 RNA pseudouridylate synthase domain-containing protein 4 protein 20090724 {GO:0005515=IPI, GO:0005739=IEA, GO:0009982=IEA, GO:0003723=IEA, GO:0001522=IEA} pseudouridine synthesis mitochondrion RNA binding, protein binding, pseudouridine synthase activity Human UniProtKB:Q9BQA5 RQCD1 Reactome UniProtKB {GO:0005515=PMID:18180299, GO:0010467=Reactome:REACT_71, GO:2000327=PMID:18180299, GO:0006355=GO_REF:0000037, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019221=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037, GO:0030014=PMID:19558367, GO:0005829=Reactome:REACT_20651, GO:0000932=GO_REF:0000024, GO:0007548=PMID:9447985, GO:0033147=PMID:16778766, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639} Q92600 Cell differentiation protein RCD1 homolog protein 20090723 {GO:0005515=IPI, GO:0010467=TAS, GO:2000327=IDA, GO:0006355=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0019221=IEA, GO:0005634=IEA, GO:0006351=IEA, GO:0030014=IDA, GO:0005829=TAS, GO:0000932=ISS, GO:0007548=TAS, GO:0033147=IMP, GO:0000289=TAS, GO:0000288=TAS} RNA metabolic process, cytokine-mediated signaling pathway, gene expression, mRNA metabolic process, negative regulation of intracellular estrogen receptor signaling pathway, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA poly(A) tail shortening, positive regulation of ligand-dependent nuclear receptor transcription coactivator activity, regulation of transcription, DNA-dependent, sex differentiation, transcription, DNA-dependent CCR4-NOT complex, cytoplasmic mRNA processing body, cytosol, nucleus protein binding Human RRAD UniProtKB UniProtKB {GO:0005515=PMID:18056528, GO:0005622=GO_REF:0000002, GO:0005516=GO_REF:0000037, GO:0007165=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037} P55042 GTP-binding protein RAD protein 20090915 {GO:0005515=IPI, GO:0005622=IEA, GO:0005516=IEA, GO:0007165=IEA, GO:0005886=IEA, GO:0016020=IEA, GO:0007264=IEA, GO:0003924=IEA, GO:0005525=IEA} signal transduction, small GTPase mediated signal transduction intracellular, membrane, plasma membrane GTP binding, GTPase activity, calmodulin binding, protein binding Human UniProtKB:P62161 RRAGA HPA UniProtKB {GO:0051219=PMID:8995684, GO:0005515=PMID:22424946, GO:0008219=PMID:9394008, GO:0005794=GO_REF:0000052, GO:0032008=PMID:20381137, GO:0046982=PMID:14660641, GO:0006915=GO_REF:0000037, GO:0005634=PMID:8995684, GO:0005525=PMID:14660641, GO:0005764=PMID:20381137, GO:0042803=PMID:14660641, GO:0043231=GO_REF:0000052, GO:0005737=PMID:9394008, GO:0071230=PMID:20381137, GO:0045919=PMID:8995684, GO:0019048=PMID:8995684, GO:0034613=PMID:20381137} Q7L523 Ras-related GTP-binding protein A protein 20101115 {GO:0051219=IDA, GO:0005515=IPI, GO:0008219=IDA, GO:0005794=IDA, GO:0032008=NAS, GO:0046982=IPI, GO:0006915=IEA, GO:0005634=IDA, GO:0005525=IDA, GO:0005764=IDA, GO:0042803=IDA, GO:0043231=IDA, GO:0005737=IDA, GO:0071230=IMP, GO:0045919=IDA, GO:0019048=IDA, GO:0034613=IMP} apoptotic process, cell death, cellular protein localization, cellular response to amino acid stimulus, positive regulation of TOR signaling cascade, positive regulation of cytolysis, virus-host interaction Golgi apparatus, cytoplasm, intracellular membrane-bounded organelle, lysosome, nucleus GTP binding, phosphoprotein binding, protein binding, protein heterodimerization activity, protein homodimerization activity Human RRAGB HPA UniProtKB {GO:0005515=PMID:22424946, GO:0005737=PMID:9394008, GO:0032008=PMID:22575674, GO:0005794=GO_REF:0000052, GO:0071230=PMID:20381137, GO:0032561=PMID:22575674, GO:0005634=GO_REF:0000002, GO:0034613=PMID:20381137, GO:0005525=PMID:7499430, GO:0005764=PMID:20381137, GO:0043231=GO_REF:0000052} Q5VZM2 Ras-related GTP-binding protein B protein 20101115 {GO:0005515=IPI, GO:0005737=IDA, GO:0032008=IMP, GO:0005794=IDA, GO:0071230=IMP, GO:0032561=IDA, GO:0005634=IEA, GO:0034613=IMP, GO:0005525=IDA, GO:0005764=IDA, GO:0043231=IDA} cellular protein localization, cellular response to amino acid stimulus, positive regulation of TOR signaling cascade Golgi apparatus, cytoplasm, intracellular membrane-bounded organelle, lysosome, nucleus GTP binding, guanyl ribonucleotide binding, protein binding Human RRAGC GOC UniProtKB {GO:0008380=PMID:11073942, GO:0005515=PMID:22424946, GO:0000287=PMID:11073942, GO:0046982=PMID:11073942, GO:0007264=PMID:11073942, GO:0003924=PMID:11073942, GO:0006915=PMID:11073942, GO:0005634=PMID:11073942, GO:0005525=PMID:11073942, GO:0005764=PMID:20381137, GO:0006351=PMID:11073942, GO:0006184=PMID:11073942, GO:0005737=PMID:11073942, GO:0071230=GO_REF:0000024, GO:0016049=PMID:11073942, GO:0034613=GO_REF:0000024, GO:0019003=PMID:11073942} Q9HB90 Ras-related GTP-binding protein C protein 20130413 {GO:0008380=NAS, GO:0005515=IPI, GO:0000287=NAS, GO:0046982=IPI, GO:0007264=TAS, GO:0003924=IDA, GO:0006915=NAS, GO:0005634=IDA, GO:0005525=IDA, GO:0005764=IDA, GO:0006351=NAS, GO:0006184=IDA, GO:0005737=IDA, GO:0071230=ISS, GO:0016049=NAS, GO:0034613=ISS, GO:0019003=IDA} GTP catabolic process, RNA splicing, apoptotic process, cell growth, cellular protein localization, cellular response to amino acid stimulus, small GTPase mediated signal transduction, transcription, DNA-dependent cytoplasm, lysosome, nucleus GDP binding, GTP binding, GTPase activity, magnesium ion binding, protein binding, protein heterodimerization activity Human RRAGD IntAct UniProtKB {GO:0005515=PMID:22424946, GO:0005737=PMID:11073942, GO:0032008=PMID:20381137, GO:0071230=GO_REF:0000024, GO:0046982=PMID:11073942, GO:0005634=PMID:11073942, GO:0034613=GO_REF:0000024, GO:0005525=GO_REF:0000037, GO:0005764=PMID:20381137} Q9NQL2 Ras-related GTP-binding protein D protein 20130415 {GO:0005515=IPI, GO:0005737=IDA, GO:0032008=NAS, GO:0071230=ISS, GO:0046982=IPI, GO:0005634=IDA, GO:0034613=ISS, GO:0005525=IEA, GO:0005764=IDA} cellular protein localization, cellular response to amino acid stimulus, positive regulation of TOR signaling cascade cytoplasm, lysosome, nucleus GTP binding, protein binding, protein heterodimerization activity Human UniProtKB:Q9P2J5 RRAS IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0030336=GO_REF:0000019, GO:0005886=Reactome:REACT_20578, GO:0007411=Reactome:REACT_18266, GO:0003924=PMID:16773572, GO:0007268=Reactome:REACT_13685, GO:0007265=PMID:3098437, GO:0019003=PMID:16773572, GO:0005525=GO_REF:0000037, GO:0045766=PMID:21393242} P10301 Ras-related protein R-Ras protein 20130415 {GO:0005515=IPI, GO:0030336=IEA, GO:0005886=TAS, GO:0007411=TAS, GO:0003924=IDA, GO:0007268=TAS, GO:0007265=TAS, GO:0019003=IDA, GO:0005525=IEA, GO:0045766=IMP} Ras protein signal transduction, axon guidance, negative regulation of cell migration, positive regulation of angiogenesis, synaptic transmission plasma membrane GDP binding, GTP binding, GTPase activity, protein binding Human UniProtKB:P16333 RRAS2 IntAct UniProtKB {GO:0005515=PMID:12620389, GO:0005622=GO_REF:0000019, GO:0030335=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0005783=PMID:10777492, GO:0007264=GO_REF:0000002, GO:0003924=GO_REF:0000002, GO:0007265=GO_REF:0000019, GO:0005525=GO_REF:0000037} P62070 Ras-related protein R-Ras2 protein 20130415 {GO:0005515=IPI, GO:0005622=IEA, GO:0030335=IEA, GO:0005886=IEA, GO:0016020=IEA, GO:0005783=NAS, GO:0007264=IEA, GO:0003924=IEA, GO:0007265=IEA, GO:0005525=IEA} Ras protein signal transduction, positive regulation of cell migration, small GTPase mediated signal transduction endoplasmic reticulum, intracellular, membrane, plasma membrane GTP binding, GTPase activity, protein binding Human UniProtKB:P10398 RRBP1 HPA UniProtKB {GO:0007165=GO_REF:0000029, GO:0005783=GO_REF:0000052, GO:0005840=PMID:9628588, GO:0004872=PMID:9628588, GO:0030176=GO_REF:0000029, GO:0015031=GO_REF:0000037, GO:0006412=PMID:9628588} Q9P2E9 Ribosome-binding protein 1 protein 20080205 {GO:0007165=NAS, GO:0005783=IDA, GO:0005840=TAS, GO:0004872=TAS, GO:0030176=NAS, GO:0015031=IEA, GO:0006412=TAS} protein transport, signal transduction, translation endoplasmic reticulum, integral to endoplasmic reticulum membrane, ribosome receptor activity Human RREB1 PINC UniProtKB {GO:0006355=PMID:9305772, GO:0003700=GO_REF:0000019, GO:0006366=PMID:8816445, GO:0007275=PMID:8816445, GO:0005634=PMID:9305772, GO:0007265=PMID:8816445, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0016604=PMID:9305772, GO:0005737=PMID:9305772, GO:0016607=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0045893=PMID:9305772, GO:0045892=GO_REF:0000019} Q92766 Ras-responsive element-binding protein 1 protein 20030904 {GO:0006355=TAS, GO:0003700=IEA, GO:0006366=TAS, GO:0007275=TAS, GO:0005634=TAS, GO:0007265=TAS, GO:0003676=IEA, GO:0003677=IEA, GO:0016604=TAS, GO:0005737=TAS, GO:0016607=IEA, GO:0008270=IEA, GO:0045893=TAS, GO:0045892=IEA} Ras protein signal transduction, multicellular organismal development, negative regulation of transcription, DNA-dependent, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter cytoplasm, nuclear body, nuclear speck, nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human RRM1 IntAct UniProtKB {GO:0005515=PMID:22632967, GO:0015949=Reactome:REACT_21330, GO:0051290=GO_REF:0000019, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_2182, GO:0006260=GO_REF:0000041, GO:0009263=GO_REF:0000024, GO:0005971=GO_REF:0000029, GO:0017076=GO_REF:0000019, GO:0005654=Reactome:REACT_642, GO:0004748=GO_REF:0000024, GO:0055114=GO_REF:0000002} P23921 Ribonucleoside-diphosphate reductase large subunit protein 20130415 {GO:0005515=IPI, GO:0015949=TAS, GO:0051290=IEA, GO:0055086=TAS, GO:0044281=TAS, GO:0005524=IEA, GO:0005829=TAS, GO:0006260=IEA, GO:0009263=ISS, GO:0005971=NAS, GO:0017076=IEA, GO:0005654=TAS, GO:0004748=ISS, GO:0055114=IEA} DNA replication, deoxyribonucleotide biosynthetic process, nucleobase-containing small molecule interconversion, nucleobase-containing small molecule metabolic process, oxidation-reduction process, protein heterotetramerization, small molecule metabolic process cytosol, nucleoplasm, ribonucleoside-diphosphate reductase complex ATP binding, protein binding, purine nucleotide binding, ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor Human UniProtKB:P31350 RRM2 IntAct UniProtKB {GO:0005515=PMID:22632967, GO:0009186=GO_REF:0000002, GO:0015949=Reactome:REACT_21330, GO:0046914=GO_REF:0000002, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_2182, GO:0006260=GO_REF:0000041, GO:0005737=GO_REF:0000029, GO:0000082=Reactome:REACT_1783, GO:0009263=GO_REF:0000024, GO:0000083=Reactome:REACT_683, GO:0016491=GO_REF:0000002, GO:0005654=Reactome:REACT_22145, GO:0004748=GO_REF:0000024, GO:0000278=Reactome:REACT_152} P31350 Ribonucleoside-diphosphate reductase subunit M2 protein 20130415 {GO:0005515=IPI, GO:0009186=IEA, GO:0015949=TAS, GO:0046914=IEA, GO:0055086=TAS, GO:0044281=TAS, GO:0005829=TAS, GO:0006260=IEA, GO:0005737=NAS, GO:0000082=TAS, GO:0009263=ISS, GO:0000083=TAS, GO:0016491=IEA, GO:0005654=TAS, GO:0004748=ISS, GO:0000278=TAS} DNA replication, G1/S transition of mitotic cell cycle, deoxyribonucleoside diphosphate metabolic process, deoxyribonucleotide biosynthetic process, mitotic cell cycle, nucleobase-containing small molecule interconversion, nucleobase-containing small molecule metabolic process, regulation of transcription involved in G1/S phase of mitotic cell cycle, small molecule metabolic process cytoplasm, cytosol, nucleoplasm oxidoreductase activity, protein binding, ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor, transition metal ion binding Human UniProtKB:Q9UM11 RRM2B HPA UniProtKB {GO:0009186=GO_REF:0000002, GO:0043066=GO_REF:0000019, GO:0015949=Reactome:REACT_21330, GO:0001822=GO_REF:0000019, GO:0009200=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0046914=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0003014=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0006281=GO_REF:0000019, GO:0009263=GO_REF:0000019, GO:0016491=GO_REF:0000002, GO:0005654=Reactome:REACT_642, GO:0004748=GO_REF:0000003, GO:0006264=GO_REF:0000019, GO:0006979=GO_REF:0000019} Q7LG56 Ribonucleoside-diphosphate reductase subunit M2 B protein 20101115 {GO:0009186=IEA, GO:0043066=IEA, GO:0015949=TAS, GO:0001822=IEA, GO:0009200=IEA, GO:0005730=IDA, GO:0046914=IEA, GO:0005634=IDA, GO:0055086=TAS, GO:0044281=TAS, GO:0003014=IEA, GO:0005737=IDA, GO:0006281=IEA, GO:0009263=IEA, GO:0016491=IEA, GO:0005654=TAS, GO:0004748=IEA, GO:0006264=IEA, GO:0006979=IEA} DNA repair, deoxyribonucleoside diphosphate metabolic process, deoxyribonucleoside triphosphate metabolic process, deoxyribonucleotide biosynthetic process, kidney development, mitochondrial DNA replication, negative regulation of apoptotic process, nucleobase-containing small molecule interconversion, nucleobase-containing small molecule metabolic process, renal system process, response to oxidative stress, small molecule metabolic process cytoplasm, nucleolus, nucleoplasm, nucleus oxidoreductase activity, ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor, transition metal ion binding Human RRN3 HPA UniProtKB {GO:0010467=Reactome:REACT_71, GO:0043066=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:0042254=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0003743=GO_REF:0000038, GO:0006361=Reactome:REACT_1974, GO:0006360=Reactome:REACT_1309, GO:0001701=GO_REF:0000019, GO:0007000=GO_REF:0000019, GO:0048872=GO_REF:0000019, GO:2000142=GO_REF:0000019, GO:0005654=Reactome:REACT_1173, GO:0045893=GO_REF:0000019, GO:0070063=GO_REF:0000019, GO:0007028=GO_REF:0000019} Q9NYV6 RNA polymerase I-specific transcription initiation factor RRN3 protein 20120912 {GO:0010467=TAS, GO:0043066=IEA, GO:0008283=IEA, GO:0042254=IEA, GO:0005730=IDA, GO:0003743=IEA, GO:0006361=TAS, GO:0006360=TAS, GO:0001701=IEA, GO:0007000=IEA, GO:0048872=IEA, GO:2000142=IEA, GO:0005654=TAS, GO:0045893=IEA, GO:0070063=IEA, GO:0007028=IEA} cell proliferation, cytoplasm organization, gene expression, homeostasis of number of cells, in utero embryonic development, negative regulation of apoptotic process, nucleolus organization, positive regulation of transcription, DNA-dependent, regulation of DNA-dependent transcription, initiation, ribosome biogenesis, transcription from RNA polymerase I promoter, transcription initiation from RNA polymerase I promoter nucleolus, nucleoplasm RNA polymerase binding, translation initiation factor activity Human RRNAD1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0000179=GO_REF:0000002} Q96FB5 Protein RRNAD1 protein 20130413 {GO:0016021=IEA, GO:0000179=IEA} integral to membrane rRNA (adenine-N6,N6-)-dimethyltransferase activity Human UniProtKB-KW:KW-0812 RRP1 HPA UniProtKB {GO:0006364=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=PMID:9192856, GO:0030688=GO_REF:0000002} P56182 Ribosomal RNA processing protein 1 homolog A protein 20100326 {GO:0006364=IEA, GO:0005730=IDA, GO:0005634=TAS, GO:0030688=IEA} rRNA processing nucleolus, nucleus, preribosome, small subunit precursor Human RRP12 UniProtKB UniProtKB {GO:0031965=GO_REF:0000039, GO:0005730=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q5JTH9 RRP12-like protein protein 20130413 {GO:0031965=IEA, GO:0005730=IEA, GO:0016021=IEA} integral to membrane, nuclear membrane, nucleolus Human UniProtKB-SubCell:SL-0182 RRP15 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9Y3B9 RRP15-like protein protein 20101115 {GO:0005739=IDA, GO:0005730=IDA, GO:0005634=IDA} mitochondrion, nucleolus, nucleus Human RRP1B HPA UniProtKB {GO:0000792=GO_REF:0000019, GO:0000791=GO_REF:0000019, GO:0010923=PMID:19389623, GO:0006364=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=PMID:16780588, GO:0030688=GO_REF:0000002, GO:0005829=PMID:16780588} Q14684 Ribosomal RNA processing protein 1 homolog B protein 20100326 {GO:0000792=IEA, GO:0000791=IEA, GO:0010923=IDA, GO:0006364=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0030688=IEA, GO:0005829=IDA} negative regulation of phosphatase activity, rRNA processing cytosol, euchromatin, heterochromatin, nucleolus, nucleus, preribosome, small subunit precursor Human RRP36 UniProtKB UniProtKB {GO:0006364=PMID:20038530, GO:0005730=PMID:20038530, GO:0042274=PMID:20038530} Q96EU6 Ribosomal RNA processing protein 36 homolog protein 20100706 {GO:0006364=IDA, GO:0005730=IDA, GO:0042274=IDA} rRNA processing, ribosomal small subunit biogenesis nucleolus Human RRP7A UniProtKB UniProtKB {GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037} Q9Y3A4 Ribosomal RNA-processing protein 7 homolog A protein 20130413 {GO:0000166=IEA, GO:0003723=IEA} RNA binding, nucleotide binding Human UniProtKB-KW:KW-0694 RRP8 HPA UniProtKB {GO:0005515=PMID:18485871, GO:0005886=GO_REF:0000052, GO:0006364=GO_REF:0000037, GO:0008168=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0033553=PMID:18485871, GO:0005634=GO_REF:0000052, GO:0008757=PMID:18485871, GO:0035064=PMID:18485871, GO:0006351=GO_REF:0000037, GO:0071158=PMID:21471221, GO:0005737=GO_REF:0000052, GO:0072332=PMID:21471221, GO:0000183=PMID:18485871, GO:0042149=PMID:21471221, GO:0046015=PMID:21471221, GO:0016568=GO_REF:0000037, GO:0005677=PMID:18485871} O43159 Ribosomal RNA-processing protein 8 protein 20111111 {GO:0005515=IPI, GO:0005886=IDA, GO:0006364=IEA, GO:0008168=IEA, GO:0005730=IDA, GO:0033553=IDA, GO:0005634=IDA, GO:0008757=TAS, GO:0035064=IDA, GO:0006351=IEA, GO:0071158=IMP, GO:0005737=IDA, GO:0072332=IMP, GO:0000183=IDA, GO:0042149=IMP, GO:0046015=IMP, GO:0016568=IEA, GO:0005677=IDA} cellular response to glucose starvation, chromatin modification, chromatin silencing at rDNA, intrinsic apoptotic signaling pathway by p53 class mediator, positive regulation of cell cycle arrest, rRNA processing, regulation of transcription by glucose, transcription, DNA-dependent chromatin silencing complex, cytoplasm, nucleolus, nucleus, plasma membrane, rDNA heterochromatin S-adenosylmethionine-dependent methyltransferase activity, methylated histone residue binding, methyltransferase activity, protein binding Human RRP9 HPA UniProtKB {GO:0006364=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0030532=PMID:9418896, GO:0005634=GO_REF:0000052, GO:0005732=PMID:9418896} O43818 U3 small nucleolar RNA-interacting protein 2 protein 20110516 {GO:0006364=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0030532=TAS, GO:0005634=IDA, GO:0005732=TAS} rRNA processing nucleolus, nucleus, small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex RNA binding NOT Human RRS1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0000794=PMID:19465021, GO:0005783=GO_REF:0000019, GO:0042254=GO_REF:0000037, GO:0005730=PMID:19465021, GO:0007080=PMID:19465021} Q15050 Ribosome biogenesis regulatory protein homolog protein 20090731 {GO:0003674=ND, GO:0000794=IDA, GO:0005783=IEA, GO:0042254=IEA, GO:0005730=IDA, GO:0007080=IMP} mitotic metaphase plate congression, ribosome biogenesis condensed nuclear chromosome, endoplasmic reticulum, nucleolus molecular_function Human RS1 PINC UniProtKB {GO:0016062=GO_REF:0000019, GO:0043325=GO_REF:0000019, GO:0005547=GO_REF:0000019, GO:0070273=GO_REF:0000019, GO:0080025=GO_REF:0000019, GO:0005546=GO_REF:0000019, GO:0007275=PMID:9326935, GO:0010842=GO_REF:0000019, GO:0032266=GO_REF:0000019, GO:0005615=PMID:10915776, GO:0001786=GO_REF:0000019, GO:0007155=GO_REF:0000037, GO:0007601=GO_REF:0000037, GO:0010314=GO_REF:0000019, GO:0019897=GO_REF:0000019} O15537 Retinoschisin protein 20030904 {GO:0016062=IEA, GO:0043325=IEA, GO:0005547=IEA, GO:0070273=IEA, GO:0080025=IEA, GO:0005546=IEA, GO:0007275=TAS, GO:0010842=IEA, GO:0032266=IEA, GO:0005615=TAS, GO:0001786=IEA, GO:0007155=IEA, GO:0007601=IEA, GO:0010314=IEA, GO:0019897=IEA} adaptation of rhodopsin mediated signaling, cell adhesion, multicellular organismal development, retina layer formation, visual perception extracellular space, extrinsic to plasma membrane phosphatidylinositol-3,4,5-trisphosphate binding, phosphatidylinositol-3,4-bisphosphate binding, phosphatidylinositol-3,5-bisphosphate binding, phosphatidylinositol-3-phosphate binding, phosphatidylinositol-4,5-bisphosphate binding, phosphatidylinositol-4-phosphate binding, phosphatidylinositol-5-phosphate binding, phosphatidylserine binding Human RSBN1 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039} Q5VWQ0 Round spermatid basic protein 1 protein 20130413 {GO:0005634=IEA} nucleus Human UniProtKB-SubCell:SL-0191 RSBN1L UniProtKB UniProtKB {GO:0005634=GO_REF:0000039} Q6PCB5 Round spermatid basic protein 1-like protein protein 20130413 {GO:0005634=IEA} nucleus Human UniProtKB-SubCell:SL-0191 RSC1A1 HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0030054=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0005903=GO_REF:0000019, GO:0050892=GO_REF:0000019, GO:0006810=PMID:8836035, GO:0008200=PMID:8836035, GO:0051051=PMID:2675563} Q92681 Regulatory solute carrier protein family 1 member 1 protein 20101115 {GO:0006355=IEA, GO:0030054=IDA, GO:0005794=IDA, GO:0005886=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0006351=IEA, GO:0043231=IDA, GO:0005903=IEA, GO:0050892=IEA, GO:0006810=TAS, GO:0008200=TAS, GO:0051051=IDA} intestinal absorption, negative regulation of transport, regulation of transcription, DNA-dependent, transcription, DNA-dependent, transport Golgi apparatus, brush border, cell junction, intracellular membrane-bounded organelle, nucleolus, nucleus, plasma membrane ion channel inhibitor activity Human RSF1 Reactome UniProtKB {GO:0005515=PMID:12972596, GO:0006352=PMID:9836642, GO:0006334=Reactome:REACT_22344, GO:0005634=PMID:12972596, GO:0031213=PMID:9836642, GO:0043392=PMID:12972596, GO:0050434=PMID:11788598, GO:0034080=Reactome:REACT_22186, GO:0042393=PMID:12972596, GO:0016584=PMID:9836642, GO:0005654=Reactome:REACT_22217, GO:0008270=GO_REF:0000002, GO:0006338=PMID:9836642, GO:0045893=PMID:11788598, GO:0045892=PMID:11944984, GO:0016887=PMID:12972596} Q96T23 Remodeling and spacing factor 1 protein 20100417 {GO:0005515=IPI, GO:0006352=IDA, GO:0006334=TAS, GO:0005634=IDA, GO:0031213=IPI, GO:0043392=IDA, GO:0050434=IDA, GO:0034080=TAS, GO:0042393=IDA, GO:0016584=IDA, GO:0005654=TAS, GO:0008270=IEA, GO:0006338=IDA, GO:0045893=IDA, GO:0045892=IDA, GO:0016887=IDA} CENP-A containing nucleosome assembly at centromere, DNA-dependent transcription, initiation, chromatin remodeling, negative regulation of DNA binding, negative regulation of transcription, DNA-dependent, nucleosome assembly, nucleosome positioning, positive regulation of transcription, DNA-dependent, positive regulation of viral transcription RSF complex, nucleoplasm, nucleus ATPase activity, histone binding, protein binding, zinc ion binding Human RSG1 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0042384=GO_REF:0000024, GO:0005929=GO_REF:0000037, GO:0005737=GO_REF:0000037, GO:0007264=GO_REF:0000002, GO:0017157=GO_REF:0000024, GO:0005932=GO_REF:0000024, GO:0034613=GO_REF:0000024, GO:0015031=GO_REF:0000037, GO:0006887=GO_REF:0000037, GO:0005525=GO_REF:0000037, GO:0031338=GO_REF:0000024} Q9BU20 REM2- and Rab-like small GTPase 1 protein 20110413 {GO:0005622=IEA, GO:0042384=ISS, GO:0005929=IEA, GO:0005737=IEA, GO:0007264=IEA, GO:0017157=ISS, GO:0005932=ISS, GO:0034613=ISS, GO:0015031=IEA, GO:0006887=IEA, GO:0005525=IEA, GO:0031338=ISS} cellular protein localization, cilium assembly, exocytosis, protein transport, regulation of exocytosis, regulation of vesicle fusion, small GTPase mediated signal transduction cilium, cytoplasm, intracellular, microtubule basal body GTP binding Human UniProtKB:Q6GNL4 RSL1D1 MGI UniProtKB {GO:0032880=PMID:17158916, GO:0003735=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0005730=GO_REF:0000039, GO:0015934=GO_REF:0000002, GO:0006412=GO_REF:0000002} O76021 Ribosomal L1 domain-containing protein 1 protein 20090406 {GO:0032880=IMP, GO:0003735=IEA, GO:0003723=IEA, GO:0005730=IEA, GO:0015934=IEA, GO:0006412=IEA} regulation of protein localization, translation large ribosomal subunit, nucleolus RNA binding, structural constituent of ribosome Human RSL24D1 UniProtKB UniProtKB {GO:0042254=GO_REF:0000037, GO:0005730=GO_REF:0000039} Q9UHA3 Probable ribosome biogenesis protein RLP24 protein 20130413 {GO:0042254=IEA, GO:0005730=IEA} ribosome biogenesis nucleolus Human UniProtKB-SubCell:SL-0188 RSPH10B2 null null {} null null null null {} null null null RSPH3 null null {} null null null null {} null null null RSPO1 BHF-UCL UniProtKB {GO:0005515=PMID:17804805, GO:0090263=PMID:17804805, GO:0002090=PMID:17804805, GO:0005102=GO_REF:0000019, GO:0030177=PMID:22575959, GO:0005634=GO_REF:0000019, GO:0060070=GO_REF:0000019, GO:0008201=GO_REF:0000019, GO:0005615=GO_REF:0000019} Q2MKA7 R-spondin-1 protein 20100930 {GO:0005515=IPI, GO:0090263=IDA, GO:0002090=IDA, GO:0005102=IEA, GO:0030177=IDA, GO:0005634=IEA, GO:0060070=IEA, GO:0008201=IEA, GO:0005615=IEA} canonical Wnt receptor signaling pathway, positive regulation of Wnt receptor signaling pathway, positive regulation of canonical Wnt receptor signaling pathway, regulation of receptor internalization extracellular space, nucleus heparin binding, protein binding, receptor binding Human UniProtKB:Q96MU8 RSPRY1 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039, GO:0008270=GO_REF:0000002} Q96DX4 RING finger and SPRY domain-containing protein 1 protein 20130413 {GO:0005576=IEA, GO:0008270=IEA} extracellular region zinc ion binding Human UniProtKB-SubCell:SL-0243 RSRC1 MGI UniProtKB {GO:0008380=PMID:15798186, GO:0005515=PMID:15798186, GO:0005737=GO_REF:0000024, GO:0016607=GO_REF:0000024, GO:0000398=PMID:15798186, GO:0000380=GO_REF:0000019, GO:0005634=GO_REF:0000024, GO:0006468=GO_REF:0000019, GO:0046677=GO_REF:0000019, GO:0006913=GO_REF:0000024} Q96IZ7 Serine/Arginine-related protein 53 protein 20080924 {GO:0008380=IDA, GO:0005515=IPI, GO:0005737=ISS, GO:0016607=ISS, GO:0000398=IDA, GO:0000380=IEA, GO:0005634=ISS, GO:0006468=IEA, GO:0046677=IEA, GO:0006913=ISS} RNA splicing, alternative mRNA splicing, via spliceosome, mRNA splicing, via spliceosome, nucleocytoplasmic transport, protein phosphorylation, response to antibiotic cytoplasm, nuclear speck, nucleus protein binding Human RSRC2 null null {} null null null null {} null null null RSU1 Reactome UniProtKB {GO:0007165=PMID:1508180, GO:0034329=Reactome:REACT_20676, GO:0007265=GO_REF:0000019, GO:0005829=Reactome:REACT_20616} Q15404 Ras suppressor protein 1 protein 20130213 {GO:0007165=TAS, GO:0034329=TAS, GO:0007265=IEA, GO:0005829=TAS} Ras protein signal transduction, cell junction assembly, signal transduction cytosol Human RTDR1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q9UHP6 Rhabdoid tumor deletion region protein 1 protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human RTEL1 Reactome UniProtKB {GO:0051539=GO_REF:0000037, GO:0006281=GO_REF:0000037, GO:0004003=PMID:18957201, GO:0000723=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0005524=PMID:18957201, GO:0003677=GO_REF:0000037, GO:0010569=PMID:18957201, GO:0046872=GO_REF:0000037} Q9NZ71 Regulator of telomere elongation helicase 1 protein 20121107 {GO:0051539=IEA, GO:0006281=IEA, GO:0004003=IMP, GO:0000723=ISS, GO:0005634=ISS, GO:0044281=TAS, GO:0005524=IMP, GO:0003677=IEA, GO:0010569=IMP, GO:0046872=IEA} DNA repair, regulation of double-strand break repair via homologous recombination, small molecule metabolic process, telomere maintenance nucleus 4 iron, 4 sulfur cluster binding, ATP binding, ATP-dependent DNA helicase activity, DNA binding, metal ion binding Human RTF1 IntAct UniProtKB {GO:0005515=PMID:20178742, GO:0006352=GO_REF:0000002, GO:0080182=GO_REF:0000019, GO:0005730=GO_REF:0000019, GO:0016570=GO_REF:0000002, GO:0005634=GO_REF:0000002, GO:0000122=GO_REF:0000024, GO:0003677=GO_REF:0000002, GO:0001711=GO_REF:0000024, GO:0051571=GO_REF:0000019, GO:0003697=PMID:18184592, GO:0045944=PMID:20178742, GO:0019827=PMID:19345177, GO:0032968=PMID:20178742, GO:0016593=PMID:20178742, GO:0016055=GO_REF:0000037} Q92541 RNA polymerase-associated protein RTF1 homolog protein 20130415 {GO:0005515=IPI, GO:0006352=IEA, GO:0080182=IEA, GO:0005730=IEA, GO:0016570=IEA, GO:0005634=IEA, GO:0000122=ISS, GO:0003677=IEA, GO:0001711=ISS, GO:0051571=IEA, GO:0003697=IDA, GO:0045944=IDA, GO:0019827=IDA, GO:0032968=IDA, GO:0016593=IDA, GO:0016055=IEA} DNA-dependent transcription, initiation, Wnt receptor signaling pathway, endodermal cell fate commitment, histone H3-K4 trimethylation, histone modification, negative regulation of transcription from RNA polymerase II promoter, positive regulation of histone H3-K4 methylation, positive regulation of transcription elongation from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter, stem cell maintenance Cdc73/Paf1 complex, nucleolus, nucleus DNA binding, protein binding, single-stranded DNA binding Human UniProtKB:Q8N7H5 RTKN UniProtKB UniProtKB {GO:0005515=PMID:16007136, GO:0007165=PMID:10940294, GO:0005543=GO_REF:0000002, GO:0006915=GO_REF:0000037, GO:0017048=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0017049=PMID:10940294, GO:0007266=PMID:15480428, GO:0005095=PMID:10940294, GO:0005525=GO_REF:0000037} Q9BST9 Rhotekin protein 20061204 {GO:0005515=IPI, GO:0007165=IDA, GO:0005543=IEA, GO:0006915=IEA, GO:0017048=IEA, GO:0005575=ND, GO:0017049=IDA, GO:0007266=IDA, GO:0005095=IDA, GO:0005525=IEA} Rho protein signal transduction, apoptotic process, signal transduction cellular_component GTP binding, GTP-Rho binding, GTPase inhibitor activity, Rho GTPase binding, phospholipid binding, protein binding Human RTKN2 ENSEMBL UniProtKB {GO:0030097=GO_REF:0000019, GO:0007165=GO_REF:0000002, GO:0008284=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0005886=GO_REF:0000019} Q8IZC4 Rhotekin-2 protein 20130413 {GO:0030097=IEA, GO:0007165=IEA, GO:0008284=IEA, GO:0005543=IEA, GO:0005886=IEA} hemopoiesis, positive regulation of cell proliferation, signal transduction plasma membrane phospholipid binding Human Ensembl:ENSMUSP00000101077 RTN1 UniProtKB UniProtKB {GO:0005515=PMID:17786215, GO:0007165=GO_REF:0000029, GO:0005783=GO_REF:0000002, GO:0030176=PMID:8833145, GO:0004871=GO_REF:0000029} Q16799 Reticulon-1 protein 20120708 {GO:0005515=IPI, GO:0007165=NAS, GO:0005783=IEA, GO:0030176=TAS, GO:0004871=NAS} signal transduction endoplasmic reticulum, integral to endoplasmic reticulum membrane protein binding, signal transducer activity Human UniProtKB:Q92597 RTN2 InterPro UniProtKB {GO:0005515=PMID:22232211, GO:0007165=GO_REF:0000029, GO:0008219=GO_REF:0000037, GO:0005783=GO_REF:0000002, GO:0030176=PMID:9693037, GO:0004871=GO_REF:0000029} Q96CG9 Reticulon-2 protein 20130413 {GO:0005515=IPI, GO:0007165=NAS, GO:0008219=IEA, GO:0005783=IEA, GO:0030176=NAS, GO:0004871=NAS} cell death, signal transduction endoplasmic reticulum, integral to endoplasmic reticulum membrane protein binding, signal transducer activity Human InterPro:IPR003388 RTN3 HPA UniProtKB {GO:0000139=GO_REF:0000039, GO:0005783=GO_REF:0000052, GO:0019048=GO_REF:0000037, GO:0071786=PMID:18779370, GO:0005789=GO_REF:0000039, GO:0006950=GO_REF:0000037, GO:0006915=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0016192=GO_REF:0000037, GO:0005615=PMID:10331947} O95197 Reticulon-3 protein 20101115 {GO:0000139=IEA, GO:0005783=IDA, GO:0019048=IEA, GO:0071786=IMP, GO:0005789=IEA, GO:0006950=IEA, GO:0006915=IEA, GO:0016021=IEA, GO:0016192=IEA, GO:0005615=TAS} apoptotic process, endoplasmic reticulum tubular network organization, response to stress, vesicle-mediated transport, virus-host interaction Golgi membrane, endoplasmic reticulum, endoplasmic reticulum membrane, extracellular space, integral to membrane Human RTN4 Reactome UniProtKB {GO:0005515=PMID:19665976, GO:0048011=Reactome:REACT_13776, GO:0030308=PMID:20463223, GO:0005886=Reactome:REACT_13732, GO:0005783=PMID:11126360, GO:0071786=PMID:18779370, GO:0006915=PMID:11126360, GO:0021801=GO_REF:0000024, GO:0042981=PMID:11126360, GO:0030176=PMID:10667797, GO:0001525=GO_REF:0000019, GO:0042995=GO_REF:0000019, GO:0005635=PMID:11126360, GO:0060317=GO_REF:0000019, GO:0007413=GO_REF:0000024, GO:0030517=PMID:10667797, GO:0043025=GO_REF:0000019, GO:0050771=Reactome:REACT_13815, GO:2000172=GO_REF:0000024, GO:0050770=Reactome:REACT_13620} Q9NQC3 Reticulon-4 protein 20130301 {GO:0005515=IPI, GO:0048011=TAS, GO:0030308=IMP, GO:0005886=TAS, GO:0005783=NAS, GO:0071786=IMP, GO:0006915=NAS, GO:0021801=ISS, GO:0042981=NAS, GO:0030176=IDA, GO:0001525=IEA, GO:0042995=IEA, GO:0005635=IDA, GO:0060317=IEA, GO:0007413=ISS, GO:0030517=IDA, GO:0043025=IEA, GO:0050771=TAS, GO:2000172=ISS, GO:0050770=TAS} angiogenesis, apoptotic process, axonal fasciculation, cardiac epithelial to mesenchymal transition, cerebral cortex radial glia guided migration, endoplasmic reticulum tubular network organization, negative regulation of axon extension, negative regulation of axonogenesis, negative regulation of cell growth, neurotrophin TRK receptor signaling pathway, regulation of apoptotic process, regulation of axonogenesis, regulation of branching morphogenesis of a nerve cell projection, endoplasmic reticulum, integral to endoplasmic reticulum membrane, neuronal cell body, nuclear envelope, plasma membrane protein binding Human RTN4IP1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0016491=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q8WWV3 Reticulon-4-interacting protein 1, mitochondrial protein 20130413 {GO:0005739=IEA, GO:0016491=IEA, GO:0008270=IEA} mitochondrion oxidoreductase activity, zinc ion binding Human UniProtKB-SubCell:SL-0173 RTN4R Reactome UniProtKB {GO:0005515=PMID:20697954, GO:0048011=Reactome:REACT_13776, GO:0005886=Reactome:REACT_13732, GO:0016020=GO_REF:0000029, GO:0009986=PMID:20463223, GO:0005783=GO_REF:0000054, GO:0050771=Reactome:REACT_13815, GO:0004872=PMID:11201742, GO:0007409=PMID:11201742, GO:0031225=GO_REF:0000037, GO:0050770=Reactome:REACT_13620} Q9BZR6 Reticulon-4 receptor protein 20130301 {GO:0005515=IPI, GO:0048011=TAS, GO:0005886=TAS, GO:0016020=NAS, GO:0009986=IDA, GO:0005783=IDA, GO:0050771=TAS, GO:0004872=NAS, GO:0007409=NAS, GO:0031225=IEA, GO:0050770=TAS} axonogenesis, negative regulation of axonogenesis, neurotrophin TRK receptor signaling pathway, regulation of axonogenesis anchored to membrane, cell surface, endoplasmic reticulum, membrane, plasma membrane protein binding, receptor activity Human RTN4RL1 UniProtKB UniProtKB {GO:0031103=PMID:14664809, GO:0009986=PMID:20463223, GO:0004872=PMID:12694398, GO:0045121=GO_REF:0000019, GO:0046658=PMID:12694398, GO:0009897=GO_REF:0000019} Q86UN2 Reticulon-4 receptor-like 1 protein 20060119 {GO:0031103=TAS, GO:0009986=IDA, GO:0004872=IDA, GO:0045121=IEA, GO:0046658=IDA, GO:0009897=IEA} axon regeneration anchored to plasma membrane, cell surface, external side of plasma membrane, membrane raft receptor activity Human RTN4RL2 UniProtKB UniProtKB {GO:0031103=PMID:14664809, GO:0009986=PMID:20463223, GO:0004872=PMID:12694398, GO:0045121=GO_REF:0000019, GO:0046658=PMID:12694398, GO:0009897=GO_REF:0000019} Q86UN3 Reticulon-4 receptor-like 2 protein 20060119 {GO:0031103=TAS, GO:0009986=IDA, GO:0004872=IDA, GO:0045121=IEA, GO:0046658=IDA, GO:0009897=IEA} axon regeneration anchored to plasma membrane, cell surface, external side of plasma membrane, membrane raft receptor activity Human RTTN UniProtKB UniProtKB {GO:0007368=GO_REF:0000019, GO:0005737=GO_REF:0000037, GO:0036064=PMID:22939636} Q86VV8 Rotatin protein 20121218 {GO:0007368=IEA, GO:0005737=IEA, GO:0036064=IDA} determination of left/right symmetry cilium basal body, cytoplasm Human RUFY1 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0030100=GO_REF:0000019, GO:0031901=GO_REF:0000039, GO:0008565=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0008289=GO_REF:0000037, GO:0006897=GO_REF:0000037} Q96T51 RUN and FYVE domain-containing protein 1 protein 20130415 {GO:0005515=IPI, GO:0030100=IEA, GO:0031901=IEA, GO:0008565=IEA, GO:0008270=IEA, GO:0008289=IEA, GO:0006897=IEA} endocytosis, regulation of endocytosis early endosome membrane lipid binding, protein binding, protein transporter activity, zinc ion binding Human UniProtKB:O75928 RUFY2 HPA UniProtKB {GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0046872=GO_REF:0000037} Q8WXA3 RUN and FYVE domain-containing protein 2 protein 20111111 {GO:0005730=IDA, GO:0005634=IDA, GO:0046872=IEA} nucleolus, nucleus metal ion binding NOT Human RUFY3 HGNC UniProtKB {GO:0050771=GO_REF:0000024, GO:0030175=GO_REF:0000024, GO:0030426=GO_REF:0000024} Q7L099 Protein RUFY3 protein 20071023 {GO:0050771=ISS, GO:0030175=ISS, GO:0030426=ISS} negative regulation of axonogenesis filopodium, growth cone Human UniProtKB:Q5FVJ0 RUNDC1 null null {} null null null null {} null null null RUNDC3A PINC UniProtKB {GO:0005083=PMID:9523700, GO:0007264=PMID:9523700} Q59EK9 RUN domain-containing protein 3A protein 20030904 {GO:0005083=TAS, GO:0007264=TAS} small GTPase mediated signal transduction small GTPase regulator activity Human RUNDC3B null null {} null null null null {} null null null RUNX1 HPA UniProtKB {GO:0005515=PMID:14970218, GO:0003700=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0043231=GO_REF:0000052, GO:0031069=GO_REF:0000019, GO:0071336=GO_REF:0000019, GO:2000872=GO_REF:0000019, GO:0030854=PMID:9199349, GO:0045944=PMID:10207087, GO:0070491=GO_REF:0000019, GO:0035162=GO_REF:0000019, GO:0030097=PMID:21873977, GO:0005730=GO_REF:0000052, GO:0060216=GO_REF:0000019, GO:0009966=GO_REF:0000019, GO:0007417=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0005524=GO_REF:0000029, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0045766=GO_REF:0000024, GO:0005604=GO_REF:0000019, GO:0001889=GO_REF:0000019, GO:0071425=PMID:21873977, GO:0001501=GO_REF:0000019, GO:0048935=PMID:20096094, GO:0002318=GO_REF:0000019, GO:0045893=PMID:10207087, GO:0048266=GO_REF:0000019} Q01196 Runt-related transcription factor 1 protein 20101115 {GO:0005515=IPI, GO:0003700=IEA, GO:0005634=IDA, GO:0043231=IDA, GO:0031069=IEA, GO:0071336=IEA, GO:2000872=IEA, GO:0030854=IMP, GO:0045944=IDA, GO:0070491=IEA, GO:0035162=IEA, GO:0030097=IDA, GO:0005730=IDA, GO:0060216=IEA, GO:0009966=IEA, GO:0007417=IEA, GO:0001701=IEA, GO:0005524=NAS, GO:0003677=IEA, GO:0006351=IEA, GO:0045766=ISS, GO:0005604=IEA, GO:0001889=IEA, GO:0071425=TAS, GO:0001501=IEA, GO:0048935=TAS, GO:0002318=IEA, GO:0045893=IDA, GO:0048266=IEA} behavioral response to pain, central nervous system development, definitive hemopoiesis, embryonic hemopoiesis, hair follicle morphogenesis, hematopoietic stem cell proliferation, hemopoiesis, in utero embryonic development, liver development, myeloid progenitor cell differentiation, peripheral nervous system neuron development, positive regulation of angiogenesis, positive regulation of granulocyte differentiation, positive regulation of progesterone secretion, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of hair follicle cell proliferation, regulation of signal transduction, skeletal system development, transcription, DNA-dependent basement membrane, intracellular membrane-bounded organelle, nucleolus, nucleus ATP binding, DNA binding, protein binding, repressing transcription factor binding, sequence-specific DNA binding transcription factor activity Human RUNX1T1 IntAct UniProtKB {GO:0005515=PMID:12874834, GO:0006355=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0005634=GO_REF:0000019, GO:0006091=PMID:9618262, GO:0003677=GO_REF:0000037, GO:0042803=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0016363=PMID:10973986, GO:0042802=PMID:16616331, GO:0051101=GO_REF:0000019, GO:0045444=GO_REF:0000019, GO:0008270=GO_REF:0000002} Q06455 Protein CBFA2T1 protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0003700=IEA, GO:0005634=IEA, GO:0006091=TAS, GO:0003677=IEA, GO:0042803=IEA, GO:0006351=IEA, GO:0016363=IDA, GO:0042802=IPI, GO:0051101=IEA, GO:0045444=IEA, GO:0008270=IEA} fat cell differentiation, generation of precursor metabolites and energy, regulation of DNA binding, regulation of transcription, DNA-dependent, transcription, DNA-dependent nuclear matrix, nucleus DNA binding, identical protein binding, protein binding, protein homodimerization activity, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB:Q06455 RUNX2 HPA UniProtKB {GO:0071773=GO_REF:0000024, GO:0005515=PMID:16299379, GO:0010467=Reactome:REACT_71, GO:0000790=GO_REF:0000024, GO:0008284=GO_REF:0000019, GO:0006367=Reactome:REACT_118713, GO:0003700=GO_REF:0000002, GO:0044212=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0045879=GO_REF:0000019, GO:0048701=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0002063=GO_REF:0000019, GO:0070491=GO_REF:0000019, GO:0042475=GO_REF:0000019, GO:0032332=GO_REF:0000019, GO:0048469=GO_REF:0000019, GO:1901522=GO_REF:0000024, GO:0005667=GO_REF:0000019, GO:0006355=GO_REF:0000002, GO:0019904=GO_REF:0000019, GO:0002051=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0043425=GO_REF:0000019, GO:0030509=GO_REF:0000024, GO:0005524=GO_REF:0000002, GO:0003677=GO_REF:0000002, GO:0001649=PMID:20128911, GO:0048863=GO_REF:0000019, GO:0045669=GO_REF:0000019, GO:0001958=GO_REF:0000019, GO:0001503=PMID:12217689, GO:0030217=GO_REF:0000019, GO:0040036=GO_REF:0000019, GO:0002076=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0042487=GO_REF:0000019, GO:0045893=PMID:11965546, GO:0045892=PMID:11965546} Q5T802 Runt-related transcription factor 2 protein 20100326 {GO:0071773=ISS, GO:0005515=IPI, GO:0010467=TAS, GO:0000790=ISS, GO:0008284=IEA, GO:0006367=TAS, GO:0003700=IEA, GO:0044212=IEA, GO:0005634=IDA, GO:0045879=IEA, GO:0048701=IEA, GO:0005737=IEA, GO:0002063=IEA, GO:0070491=IEA, GO:0042475=IEA, GO:0032332=IEA, GO:0048469=IEA, GO:1901522=ISS, GO:0005667=IEA, GO:0006355=IEA, GO:0019904=IEA, GO:0002051=IEA, GO:0005730=IDA, GO:0043425=IEA, GO:0030509=ISS, GO:0005524=IEA, GO:0003677=IEA, GO:0001649=IEP, GO:0048863=IEA, GO:0045669=IEA, GO:0001958=IEA, GO:0001503=TAS, GO:0030217=IEA, GO:0040036=IEA, GO:0002076=IEA, GO:0003682=IEA, GO:0042487=IEA, GO:0045893=IDA, GO:0045892=IDA} BMP signaling pathway, T cell differentiation, cell maturation, cellular response to BMP stimulus, chondrocyte development, embryonic cranial skeleton morphogenesis, endochondral ossification, gene expression, negative regulation of smoothened signaling pathway, negative regulation of transcription, DNA-dependent, odontogenesis of dentin-containing tooth, ossification, osteoblast development, osteoblast differentiation, osteoblast fate commitment, positive regulation of cell proliferation, positive regulation of chondrocyte differentiation, positive regulation of osteoblast differentiation, positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus, positive regulation of transcription, DNA-dependent, regulation of fibroblast growth factor receptor signaling pathway, regulation of odontogenesis of dentin-containing tooth, regulation of transcription, DNA-dependent, stem cell differentiation, transcription initiation from RNA polymerase II promoter cytoplasm, nuclear chromatin, nucleolus, nucleus, transcription factor complex ATP binding, DNA binding, bHLH transcription factor binding, chromatin binding, protein binding, protein domain specific binding, repressing transcription factor binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding NOT Human RUNX3 BHF-UCL UniProtKB {GO:0005515=PMID:9751710, GO:0000790=GO_REF:0000024, GO:0006355=PMID:7622058, GO:0000977=GO_REF:0000024, GO:0003700=PMID:7607690, GO:0006366=PMID:7607690, GO:0000981=GO_REF:0000024, GO:0050680=GO_REF:0000024, GO:0005634=PMID:20100835, GO:0000122=GO_REF:0000024, GO:0006917=GO_REF:0000024, GO:0045786=GO_REF:0000024, GO:0003677=GO_REF:0000002, GO:0005524=PMID:7835892, GO:0031069=GO_REF:0000019, GO:0005737=PMID:20100835, GO:0007411=GO_REF:0000019, GO:0048935=PMID:20096094, GO:0006468=PMID:20100835, GO:0048469=GO_REF:0000019, GO:0032609=GO_REF:0000019} Q13761 Runt-related transcription factor 3 protein 20120917 {GO:0005515=IPI, GO:0000790=ISS, GO:0006355=NAS, GO:0000977=ISS, GO:0003700=TAS, GO:0006366=TAS, GO:0000981=ISS, GO:0050680=ISS, GO:0005634=IDA, GO:0000122=ISS, GO:0006917=ISS, GO:0045786=ISS, GO:0003677=IEA, GO:0005524=NAS, GO:0031069=IEA, GO:0005737=IDA, GO:0007411=IEA, GO:0048935=TAS, GO:0006468=IDA, GO:0048469=IEA, GO:0032609=IEA} axon guidance, cell maturation, hair follicle morphogenesis, induction of apoptosis, interferon-gamma production, negative regulation of cell cycle, negative regulation of epithelial cell proliferation, negative regulation of transcription from RNA polymerase II promoter, peripheral nervous system neuron development, protein phosphorylation, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter cytoplasm, nuclear chromatin, nucleus ATP binding, DNA binding, RNA polymerase II regulatory region sequence-specific DNA binding, protein binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity Human UniProtKB:Q64131 RUSC1 HPA UniProtKB {GO:0000209=PMID:19365808, GO:0030054=GO_REF:0000037, GO:0005794=GO_REF:0000024, GO:0005886=GO_REF:0000037, GO:0005874=GO_REF:0000037, GO:0014069=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0003779=GO_REF:0000024, GO:0031410=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0005070=PMID:10760598, GO:0045211=GO_REF:0000037, GO:0015630=GO_REF:0000024, GO:0016023=GO_REF:0000039, GO:0005769=GO_REF:0000024} Q9BVN2 RUN and SH3 domain-containing protein 1 protein 20110516 {GO:0000209=IDA, GO:0030054=IEA, GO:0005794=ISS, GO:0005886=IEA, GO:0005874=IEA, GO:0014069=IEA, GO:0005634=IEA, GO:0003779=ISS, GO:0031410=ISS, GO:0005737=IDA, GO:0005070=TAS, GO:0045211=IEA, GO:0015630=ISS, GO:0016023=IEA, GO:0005769=ISS} protein polyubiquitination Golgi apparatus, cell junction, cytoplasm, cytoplasmic membrane-bounded vesicle, cytoplasmic vesicle, early endosome, microtubule, microtubule cytoskeleton, nucleus, plasma membrane, postsynaptic density, postsynaptic membrane SH3/SH2 adaptor activity, actin binding Human RUSC2 UniProtKB UniProtKB {GO:0005829=GO_REF:0000039} Q8N2Y8 Iporin protein 20130413 {GO:0005829=IEA} cytosol Human UniProtKB-SubCell:SL-0091 RUVBL1 HPA UniProtKB {GO:0005515=PMID:20371770, GO:0005634=GO_REF:0000052, GO:0007283=PMID:9588198, GO:0016363=GO_REF:0000039, GO:0043231=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0071339=PMID:15960975, GO:0035267=PMID:14966270, GO:0032508=PMID:9843967, GO:0016887=PMID:10966108, GO:0005794=GO_REF:0000052, GO:0043141=GO_REF:0000002, GO:0005815=GO_REF:0000039, GO:0006357=PMID:9813143, GO:0006334=Reactome:REACT_22344, GO:0005730=GO_REF:0000052, GO:0006310=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0003678=PMID:9843967, GO:0034080=Reactome:REACT_22186, GO:0031011=PMID:21303910, GO:0007067=GO_REF:0000037, GO:0006281=GO_REF:0000037, GO:0016020=GO_REF:0000039, GO:0043967=PMID:14966270, GO:0043968=PMID:14966270, GO:0005654=Reactome:REACT_22217, GO:0040008=GO_REF:0000037, GO:0051301=GO_REF:0000037} Q9Y265 RuvB-like 1 protein 20101115 {GO:0005515=IPI, GO:0005634=IDA, GO:0007283=TAS, GO:0016363=IEA, GO:0043231=IDA, GO:0005737=IDA, GO:0071339=IDA, GO:0035267=IDA, GO:0032508=IDA, GO:0016887=IDA, GO:0005794=IDA, GO:0043141=IEA, GO:0005815=IEA, GO:0006357=TAS, GO:0006334=TAS, GO:0005730=IDA, GO:0006310=IEA, GO:0005524=IEA, GO:0006351=IEA, GO:0003678=IDA, GO:0034080=TAS, GO:0031011=IDA, GO:0007067=IEA, GO:0006281=IEA, GO:0016020=IEA, GO:0043967=IDA, GO:0043968=IDA, GO:0005654=TAS, GO:0040008=IEA, GO:0051301=IEA} CENP-A containing nucleosome assembly at centromere, DNA duplex unwinding, DNA recombination, DNA repair, cell division, histone H2A acetylation, histone H4 acetylation, mitosis, nucleosome assembly, regulation of growth, regulation of transcription from RNA polymerase II promoter, spermatogenesis, transcription, DNA-dependent Golgi apparatus, Ino80 complex, MLL1 complex, NuA4 histone acetyltransferase complex, cytoplasm, intracellular membrane-bounded organelle, membrane, microtubule organizing center, nuclear matrix, nucleolus, nucleoplasm, nucleus ATP binding, ATP-dependent 5'-3' DNA helicase activity, ATPase activity, DNA helicase activity, protein binding Human RUVBL2 GOC UniProtKB {GO:0005515=PMID:20371770, GO:0006200=PMID:10966108, GO:0005634=PMID:18026119, GO:0016363=GO_REF:0000039, GO:0042802=PMID:21988832, GO:0005622=GO_REF:0000054, GO:0005737=GO_REF:0000039, GO:0034644=PMID:18026119, GO:0004003=PMID:10428817, GO:0006457=PMID:10524211, GO:0071339=PMID:15960975, GO:0035267=PMID:14966270, GO:0032508=PMID:10524211, GO:0016887=PMID:10966108, GO:0006355=GO_REF:0000037, GO:0043141=GO_REF:0000002, GO:0006310=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0003678=PMID:10524211, GO:0003684=GO_REF:0000002, GO:0031011=PMID:21303910, GO:0006281=GO_REF:0000037, GO:0016020=GO_REF:0000039, GO:0043967=PMID:14966270, GO:0030529=GO_REF:0000019, GO:0043968=PMID:14966270, GO:0051082=PMID:10524211, GO:0040008=GO_REF:0000037} Q9Y230 RuvB-like 2 protein 20130413 {GO:0005515=IPI, GO:0006200=IDA, GO:0005634=IDA, GO:0016363=IEA, GO:0042802=IPI, GO:0005622=IDA, GO:0005737=IEA, GO:0034644=IMP, GO:0004003=TAS, GO:0006457=TAS, GO:0071339=IDA, GO:0035267=IDA, GO:0032508=IDA, GO:0016887=IDA, GO:0006355=IEA, GO:0043141=IEA, GO:0006310=IEA, GO:0005524=IEA, GO:0006351=IEA, GO:0003678=IDA, GO:0003684=IEA, GO:0031011=IDA, GO:0006281=IEA, GO:0016020=IEA, GO:0043967=IDA, GO:0030529=IEA, GO:0043968=IDA, GO:0051082=TAS, GO:0040008=IEA} ATP catabolic process, DNA duplex unwinding, DNA recombination, DNA repair, cellular response to UV, histone H2A acetylation, histone H4 acetylation, protein folding, regulation of growth, regulation of transcription, DNA-dependent, transcription, DNA-dependent Ino80 complex, MLL1 complex, NuA4 histone acetyltransferase complex, cytoplasm, intracellular, membrane, nuclear matrix, nucleus, ribonucleoprotein complex ATP binding, ATP-dependent 5'-3' DNA helicase activity, ATP-dependent DNA helicase activity, ATPase activity, DNA helicase activity, damaged DNA binding, identical protein binding, protein binding, unfolded protein binding Human RWDD1 IntAct UniProtKB {GO:0005515=PMID:16189514} Q9H446 RWD domain-containing protein 1 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:Q9Y295 RWDD2B UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} P57060 RWD domain-containing protein 2B protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human RWDD3 IntAct UniProtKB {GO:0005515=PMID:17956732, GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039} Q9Y3V2 RWD domain-containing protein 3 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0005634=IEA} cytoplasm, nucleus protein binding Human UniProtKB:P63279 RWDD4 null null {} null null null null {} null null null RXFP1 Reactome UniProtKB {GO:0060427=GO_REF:0000019, GO:0060658=GO_REF:0000019, GO:0005886=Reactome:REACT_22268, GO:0007567=GO_REF:0000019, GO:0030198=GO_REF:0000019, GO:0004930=PMID:11809971, GO:0042562=GO_REF:0000019, GO:0007188=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0030154=GO_REF:0000019} Q9HBX9 Relaxin receptor 1 protein 20091026 {GO:0060427=IEA, GO:0060658=IEA, GO:0005886=TAS, GO:0007567=IEA, GO:0030198=IEA, GO:0004930=IDA, GO:0042562=IEA, GO:0007188=IEA, GO:0016021=IEA, GO:0046872=IEA, GO:0030154=IEA} adenylate cyclase-modulating G-protein coupled receptor signaling pathway, cell differentiation, extracellular matrix organization, lung connective tissue development, nipple morphogenesis, parturition integral to membrane, plasma membrane G-protein coupled receptor activity, hormone binding, metal ion binding Human RXFP2 Reactome UniProtKB {GO:0043066=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0005886=Reactome:REACT_22268, GO:0030819=GO_REF:0000019, GO:0007189=GO_REF:0000019, GO:0001556=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0017046=GO_REF:0000019, GO:0007193=GO_REF:0000019, GO:0008584=GO_REF:0000019, GO:0016500=GO_REF:0000019} Q8WXD0 Relaxin receptor 2 protein 20091026 {GO:0043066=IEA, GO:0008285=IEA, GO:0005886=TAS, GO:0030819=IEA, GO:0007189=IEA, GO:0001556=IEA, GO:0016021=IEA, GO:0017046=IEA, GO:0007193=IEA, GO:0008584=IEA, GO:0016500=IEA} adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, male gonad development, negative regulation of apoptotic process, negative regulation of cell proliferation, oocyte maturation, positive regulation of cAMP biosynthetic process integral to membrane, plasma membrane peptide hormone binding, protein-hormone receptor activity Human RXFP3 Reactome UniProtKB {GO:0004982=GO_REF:0000002, GO:0005886=Reactome:REACT_22289, GO:0007186=PMID:10806363, GO:0005887=PMID:10806363, GO:0004930=PMID:10806363, GO:0051482=GO_REF:0000019} Q9NSD7 Relaxin-3 receptor 1 protein 20091026 {GO:0004982=IEA, GO:0005886=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0004930=TAS, GO:0051482=IEA} G-protein coupled receptor signaling pathway, elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway integral to plasma membrane, plasma membrane G-protein coupled receptor activity, N-formyl peptide receptor activity Human RXFP4 Reactome UniProtKB {GO:0004945=GO_REF:0000002, GO:0005886=Reactome:REACT_22289, GO:0016021=GO_REF:0000037} Q8TDU9 Relaxin-3 receptor 2 protein 20091026 {GO:0004945=IEA, GO:0005886=TAS, GO:0016021=IEA} integral to membrane, plasma membrane angiotensin type II receptor activity Human RXRA BHF-UCL UniProtKB {GO:0005515=PMID:17363140, GO:0010467=Reactome:REACT_71, GO:0000790=PMID:18511497, GO:0006367=Reactome:REACT_15525, GO:0003700=PMID:17426122, GO:0055010=GO_REF:0000019, GO:0044212=PMID:18511497, GO:0055012=GO_REF:0000019, GO:0003707=GO_REF:0000002, GO:0005634=PMID:7990953, GO:0035357=PMID:10195690, GO:0003708=PMID:18544046, GO:0044281=Reactome:REACT_111217, GO:0042809=PMID:17426122, GO:0045944=PMID:12037571, GO:0032526=PMID:17538076, GO:0004879=PMID:7990953, GO:0044255=Reactome:REACT_22279, GO:0060528=GO_REF:0000019, GO:0008203=PMID:18544046, GO:0046982=PMID:19917671, GO:0007566=GO_REF:0000019, GO:0003713=PMID:1651173, GO:0001893=GO_REF:0000019, GO:0044323=PMID:19917671, GO:0000122=PMID:17426122, GO:0003677=PMID:12037571, GO:0001701=GO_REF:0000019, GO:0031490=GO_REF:0000019, GO:0060038=GO_REF:0000019, GO:0060687=GO_REF:0000019, GO:0048384=PMID:17538076, GO:0043565=GO_REF:0000019, GO:0006766=PMID:1651173, GO:0019048=PMID:11915042, GO:0005654=Reactome:REACT_27277, GO:0008270=GO_REF:0000002, GO:0070644=PMID:17426122, GO:0019899=PMID:12039952, GO:0004886=GO_REF:0000019, GO:0008134=GO_REF:0000019} P19793 Retinoic acid receptor RXR-alpha protein 20080624 {GO:0005515=IPI, GO:0010467=TAS, GO:0000790=IDA, GO:0006367=TAS, GO:0003700=IDA, GO:0055010=IEA, GO:0044212=IDA, GO:0055012=IEA, GO:0003707=IEA, GO:0005634=IDA, GO:0035357=IDA, GO:0003708=TAS, GO:0044281=TAS, GO:0042809=IPI, GO:0045944=IDA, GO:0032526=IMP, GO:0004879=IDA, GO:0044255=TAS, GO:0060528=IEA, GO:0008203=TAS, GO:0046982=IDA, GO:0007566=IEA, GO:0003713=TAS, GO:0001893=IEA, GO:0044323=IDA, GO:0000122=IDA, GO:0003677=IDA, GO:0001701=IEA, GO:0031490=IEA, GO:0060038=IEA, GO:0060687=IEA, GO:0048384=IMP, GO:0043565=IEA, GO:0006766=TAS, GO:0019048=IDA, GO:0005654=TAS, GO:0008270=IEA, GO:0070644=IDA, GO:0019899=IPI, GO:0004886=IEA, GO:0008134=IEA} cardiac muscle cell proliferation, cellular lipid metabolic process, cholesterol metabolic process, embryo implantation, gene expression, in utero embryonic development, maternal placenta development, negative regulation of transcription from RNA polymerase II promoter, peroxisome proliferator activated receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, regulation of branching involved in prostate gland morphogenesis, response to retinoic acid, retinoic acid receptor signaling pathway, secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development, small molecule metabolic process, transcription initiation from RNA polymerase II promoter, ventricular cardiac muscle cell differentiation, ventricular cardiac muscle tissue morphogenesis, virus-host interaction, vitamin metabolic process nuclear chromatin, nucleoplasm, nucleus 9-cis retinoic acid receptor activity, DNA binding, chromatin DNA binding, enzyme binding, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, protein binding, protein heterodimerization activity, retinoic acid receptor activity, retinoic acid-responsive element binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity, transcription coactivator activity, transcription factor binding, transcription regulatory region DNA binding, vitamin D receptor binding, vitamin D response element binding, zinc ion binding Human RXRB BHF-UCL UniProtKB {GO:0005515=PMID:20195357, GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_15525, GO:0003700=PMID:1662118, GO:0044212=GO_REF:0000019, GO:0071300=GO_REF:0000019, GO:0055012=GO_REF:0000019, GO:0003713=PMID:1662118, GO:0003707=GO_REF:0000002, GO:0001893=GO_REF:0000019, GO:0005634=PMID:7990953, GO:0001701=GO_REF:0000019, GO:0006351=GO_REF:0000038, GO:0060038=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0005654=Reactome:REACT_19207, GO:0008270=GO_REF:0000002, GO:0004879=PMID:7990953, GO:0004886=GO_REF:0000019} P28702 Retinoic acid receptor RXR-beta protein 20120116 {GO:0005515=IPI, GO:0010467=TAS, GO:0006367=TAS, GO:0003700=NAS, GO:0044212=IEA, GO:0071300=IEA, GO:0055012=IEA, GO:0003713=TAS, GO:0003707=IEA, GO:0001893=IEA, GO:0005634=IDA, GO:0001701=IEA, GO:0006351=IEA, GO:0060038=IEA, GO:0043565=IEA, GO:0045944=IEA, GO:0005654=TAS, GO:0008270=IEA, GO:0004879=IDA, GO:0004886=IEA} cardiac muscle cell proliferation, cellular response to retinoic acid, gene expression, in utero embryonic development, maternal placenta development, positive regulation of transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, ventricular cardiac muscle cell differentiation nucleoplasm, nucleus 9-cis retinoic acid receptor activity, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity, transcription coactivator activity, transcription regulatory region DNA binding, zinc ion binding Human RXRG Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_15525, GO:0003707=GO_REF:0000002, GO:0007507=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0007519=GO_REF:0000019, GO:0030182=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0007422=GO_REF:0000019, GO:0031641=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_19207, GO:0032526=GO_REF:0000019, GO:0004886=GO_REF:0000019} P48443 Retinoic acid receptor RXR-gamma protein 20130301 {GO:0010467=TAS, GO:0006367=TAS, GO:0003707=IEA, GO:0007507=IEA, GO:0043565=IEA, GO:0007519=IEA, GO:0030182=IEA, GO:0045944=IEA, GO:0007422=IEA, GO:0031641=IEA, GO:0008270=IEA, GO:0005654=TAS, GO:0032526=IEA, GO:0004886=IEA} gene expression, heart development, neuron differentiation, peripheral nervous system development, positive regulation of transcription from RNA polymerase II promoter, regulation of myelination, response to retinoic acid, skeletal muscle tissue development, transcription initiation from RNA polymerase II promoter nucleoplasm 9-cis retinoic acid receptor activity, sequence-specific DNA binding, steroid hormone receptor activity, zinc ion binding Human RYBP IntAct UniProtKB {GO:0031519=PMID:16943429, GO:0005515=PMID:16943429, GO:0035518=PMID:16943429, GO:0005737=GO_REF:0000039, GO:0003714=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0007275=PMID:10369680, GO:0005654=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0000122=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q8N488 RING1 and YY1-binding protein protein 20130415 {GO:0031519=IDA, GO:0005515=IPI, GO:0035518=IDA, GO:0005737=IEA, GO:0003714=IEA, GO:0006915=IEA, GO:0007275=TAS, GO:0005654=IEA, GO:0008270=IEA, GO:0000122=IEA, GO:0003677=IEA, GO:0006351=IEA} apoptotic process, histone H2A monoubiquitination, multicellular organismal development, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent PcG protein complex, cytoplasm, nucleoplasm DNA binding, protein binding, transcription corepressor activity, zinc ion binding Human UniProtKB:Q06587 RYK PINC UniProtKB {GO:0005515=PMID:15454084, GO:0017147=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0071679=GO_REF:0000019, GO:0048843=GO_REF:0000019, GO:0048705=GO_REF:0000019, GO:0005634=GO_REF:0000024, GO:0031175=GO_REF:0000024, GO:0005109=GO_REF:0000019, GO:0005737=GO_REF:0000024, GO:0007411=GO_REF:0000024, GO:0030182=GO_REF:0000024, GO:0016055=GO_REF:0000019, GO:0042813=GO_REF:0000019, GO:0050919=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0007165=PMID:8386829, GO:0022038=GO_REF:0000024, GO:0004672=GO_REF:0000002, GO:0016020=GO_REF:0000024, GO:0005887=PMID:8386829, GO:0006468=PMID:10454588, GO:0004713=PMID:10454588, GO:0016021=PMID:8726462, GO:0043410=PMID:10454588, GO:0004714=PMID:8386829, GO:0004888=PMID:10454588} P34925 Tyrosine-protein kinase RYK protein 20030904 {GO:0005515=IPI, GO:0017147=IEA, GO:0005886=IEA, GO:0071679=IEA, GO:0048843=IEA, GO:0048705=IEA, GO:0005634=ISS, GO:0031175=ISS, GO:0005109=IEA, GO:0005737=ISS, GO:0007411=ISS, GO:0030182=ISS, GO:0016055=IEA, GO:0042813=IEA, GO:0050919=IEA, GO:0005524=IEA, GO:0007165=TAS, GO:0022038=ISS, GO:0004672=IEA, GO:0016020=ISS, GO:0005887=TAS, GO:0006468=IDA, GO:0004713=IDA, GO:0016021=NAS, GO:0043410=IDA, GO:0004714=TAS, GO:0004888=IDA} Wnt receptor signaling pathway, axon guidance, commissural neuron axon guidance, corpus callosum development, negative chemotaxis, negative regulation of axon extension involved in axon guidance, neuron differentiation, neuron projection development, positive regulation of MAPK cascade, protein phosphorylation, signal transduction, skeletal system morphogenesis cytoplasm, integral to membrane, integral to plasma membrane, membrane, nucleus, plasma membrane ATP binding, Wnt-activated receptor activity, Wnt-protein binding, frizzled binding, protein binding, protein kinase activity, protein tyrosine kinase activity, transmembrane receptor protein tyrosine kinase activity, transmembrane signaling receptor activity Human RYR1 BHF-UCL UniProtKB {GO:0005516=GO_REF:0000024, GO:0043931=GO_REF:0000024, GO:0005886=PMID:11206130, GO:0002020=GO_REF:0000019, GO:0014701=PMID:19095005, GO:0005737=PMID:11206130, GO:0031000=GO_REF:0000024, GO:0034220=Reactome:REACT_25300, GO:0006936=GO_REF:0000024, GO:0015278=PMID:9030597, GO:0006816=GO_REF:0000024, GO:0005938=PMID:11206130, GO:0001666=PMID:19120137, GO:0005262=GO_REF:0000024, GO:0051209=GO_REF:0000024, GO:0014802=PMID:1374404, GO:0005245=GO_REF:0000024, GO:0051480=GO_REF:0000024, GO:0030314=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0006874=GO_REF:0000002, GO:0030315=GO_REF:0000019, GO:0033017=Reactome:REACT_160216, GO:0048741=GO_REF:0000024, GO:0071313=GO_REF:0000024, GO:0014808=GO_REF:0000024, GO:0055085=Reactome:REACT_15518, GO:0003151=GO_REF:0000024, GO:0005790=PMID:2298749, GO:0016529=GO_REF:0000024, GO:0016020=GO_REF:0000002, GO:0005887=PMID:2298749, GO:0043588=GO_REF:0000024, GO:0016021=GO_REF:0000002, GO:0005219=GO_REF:0000024, GO:0031674=PMID:11206130} P21817 Ryanodine receptor 1 protein 20090305 {GO:0005516=ISS, GO:0043931=ISS, GO:0005886=IDA, GO:0002020=IEA, GO:0014701=TAS, GO:0005737=IDA, GO:0031000=ISS, GO:0034220=TAS, GO:0006936=ISS, GO:0015278=TAS, GO:0006816=ISS, GO:0005938=IDA, GO:0001666=IDA, GO:0005262=ISS, GO:0051209=ISS, GO:0014802=ISS, GO:0005245=ISS, GO:0051480=ISS, GO:0030314=IEA, GO:0005509=IEA, GO:0006874=IEA, GO:0030315=IEA, GO:0033017=TAS, GO:0048741=ISS, GO:0071313=ISS, GO:0014808=ISS, GO:0055085=TAS, GO:0003151=ISS, GO:0005790=TAS, GO:0016529=ISS, GO:0016020=IEA, GO:0005887=TAS, GO:0043588=ISS, GO:0016021=IEA, GO:0005219=ISS, GO:0031674=IDA} calcium ion transport, cellular calcium ion homeostasis, cellular response to caffeine, cytosolic calcium ion homeostasis, ion transmembrane transport, muscle contraction, ossification involved in bone maturation, outflow tract morphogenesis, release of sequestered calcium ion into cytosol, release of sequestered calcium ion into cytosol by sarcoplasmic reticulum, response to caffeine, response to hypoxia, skeletal muscle fiber development, skin development, transmembrane transport I band, T-tubule, cell cortex, cytoplasm, integral to membrane, integral to plasma membrane, junctional membrane complex, junctional sarcoplasmic reticulum membrane, membrane, plasma membrane, sarcoplasmic reticulum, sarcoplasmic reticulum membrane, smooth endoplasmic reticulum, terminal cisterna calcium channel activity, calcium ion binding, calcium-release channel activity, calmodulin binding, protease binding, ryanodine-sensitive calcium-release channel activity, voltage-gated calcium channel activity Human UniProtKB:P11716 RYR2 BHF-UCL UniProtKB {GO:0005515=PMID:10830164, GO:0005516=PMID:23040497, GO:0030018=GO_REF:0000019, GO:0005513=PMID:10830164, GO:0035584=PMID:17921453, GO:0019722=GO_REF:0000024, GO:0060402=PMID:17921453, GO:0043621=GO_REF:0000019, GO:0060048=PMID:10830164, GO:0042802=PMID:10830164, GO:0003143=GO_REF:0000024, GO:0034220=Reactome:REACT_25300, GO:0015278=PMID:17921453, GO:0086029=GO_REF:0000024, GO:0086005=GO_REF:0000024, GO:0005262=GO_REF:0000024, GO:0051209=PMID:17921453, GO:0005509=GO_REF:0000002, GO:0071313=PMID:12919952, GO:0014808=PMID:12919952, GO:0030509=GO_REF:0000019, GO:0086064=GO_REF:0000036, GO:0043924=PMID:19220289, GO:0044325=GO_REF:0000024, GO:0043234=PMID:18468998, GO:0002027=PMID:11159936, GO:0055117=PMID:11159936, GO:0010460=GO_REF:0000019, GO:0005219=PMID:17921453, GO:0005218=GO_REF:0000024, GO:0034236=PMID:10830164, GO:0034237=PMID:10830164, GO:0005886=GO_REF:0000024, GO:1901896=PMID:12443530, GO:0070296=PMID:19095005, GO:0086094=GO_REF:0000024, GO:0051284=PMID:12919952, GO:0003300=GO_REF:0000024, GO:0003220=GO_REF:0000024, GO:0014701=PMID:17569730, GO:0031000=PMID:17921453, GO:0006816=PMID:17921453, GO:0060070=GO_REF:0000019, GO:0001666=GO_REF:0000024, GO:0048763=PMID:17921453, GO:0051480=GO_REF:0000024, GO:0006874=GO_REF:0000024, GO:0010881=PMID:19220289, GO:0033017=PMID:19095005, GO:0034704=PMID:10830164, GO:0055085=Reactome:REACT_15518, GO:0016529=PMID:12919952, GO:0016020=PMID:12443530, GO:0051775=PMID:19226252, GO:0016021=GO_REF:0000038, GO:0008627=PMID:15044459} Q92736 Ryanodine receptor 2 protein 20130213 {GO:0005515=IPI, GO:0005516=IPI, GO:0030018=IEA, GO:0005513=IDA, GO:0035584=IDA, GO:0019722=ISS, GO:0060402=IDA, GO:0043621=IEA, GO:0060048=IMP, GO:0042802=IPI, GO:0003143=ISS, GO:0034220=TAS, GO:0015278=IDA, GO:0086029=ISS, GO:0086005=ISS, GO:0005262=ISS, GO:0051209=IDA, GO:0005509=IEA, GO:0071313=IDA, GO:0014808=IMP, GO:0030509=IEA, GO:0086064=IC, GO:0043924=IMP, GO:0044325=ISS, GO:0043234=IDA, GO:0002027=IMP, GO:0055117=IMP, GO:0010460=IEA, GO:0005219=IDA, GO:0005218=ISS, GO:0034236=IDA, GO:0034237=IDA, GO:0005886=ISS, GO:1901896=IDA, GO:0070296=TAS, GO:0086094=ISS, GO:0051284=IDA, GO:0003300=ISS, GO:0003220=ISS, GO:0014701=TAS, GO:0031000=IDA, GO:0006816=IDA, GO:0060070=IEA, GO:0001666=ISS, GO:0048763=IDA, GO:0051480=ISS, GO:0006874=ISS, GO:0010881=IC, GO:0033017=TAS, GO:0034704=IDA, GO:0055085=TAS, GO:0016529=IDA, GO:0016020=IDA, GO:0051775=IDA, GO:0016021=IEA, GO:0008627=IDA} BMP signaling pathway, Purkinje myocyte to ventricular cardiac muscle cell signaling, calcium ion transport, calcium ion transport into cytosol, calcium-mediated signaling, calcium-mediated signaling using intracellular calcium source, canonical Wnt receptor signaling pathway, cardiac muscle contraction, cardiac muscle hypertrophy, cell communication by electrical coupling involved in cardiac conduction, cellular calcium ion homeostasis, cellular response to caffeine, cytosolic calcium ion homeostasis, detection of calcium ion, embryonic heart tube morphogenesis, intrinsic apoptotic signaling pathway in response to osmotic stress, ion transmembrane transport, left ventricular cardiac muscle tissue morphogenesis, positive regulation of calcium-transporting ATPase activity, positive regulation of heart rate, positive regulation of ryanodine-sensitive calcium-release channel activity by adrenergic receptor signaling pathway involved in positive regulation of cardiac muscle contraction, positive regulation of sequestering of calcium ion, regulation of cardiac muscle contraction, regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion, regulation of heart rate, regulation of ventricular cardiac muscle cell action potential, release of sequestered calcium ion into cytosol, release of sequestered calcium ion into cytosol by sarcoplasmic reticulum, response to caffeine, response to hypoxia, response to redox state, sarcoplasmic reticulum calcium ion transport, transmembrane transport Z disc, calcium channel complex, integral to membrane, junctional sarcoplasmic reticulum membrane, membrane, plasma membrane, protein complex, sarcoplasmic reticulum, sarcoplasmic reticulum membrane calcium channel activity, calcium ion binding, calcium-induced calcium release activity, calcium-release channel activity, calmodulin binding, identical protein binding, intracellular ligand-gated calcium channel activity, ion channel binding, protein binding, protein kinase A catalytic subunit binding, protein kinase A regulatory subunit binding, protein self-association, ryanodine-sensitive calcium-release channel activity, suramin binding Human UniProtKB:F1PEE8 RYR3 BHF-UCL UniProtKB {GO:0005516=GO_REF:0000037, GO:0030314=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0071286=GO_REF:0000024, GO:0006874=GO_REF:0000019, GO:0006941=GO_REF:0000019, GO:0033017=Reactome:REACT_160216, GO:0071313=GO_REF:0000024, GO:0055085=Reactome:REACT_15518, GO:0071318=GO_REF:0000024, GO:0034220=Reactome:REACT_25300, GO:0051289=GO_REF:0000024, GO:0070588=GO_REF:0000024, GO:0071277=GO_REF:0000024, GO:0015278=PMID:9395096, GO:0006816=PMID:9395096, GO:0016021=GO_REF:0000024, GO:0005219=PMID:19095005} Q15413 Ryanodine receptor 3 protein 20090203 {GO:0005516=IEA, GO:0030314=IEA, GO:0005509=IEA, GO:0071286=ISS, GO:0006874=IEA, GO:0006941=IEA, GO:0033017=TAS, GO:0071313=ISS, GO:0055085=TAS, GO:0071318=ISS, GO:0034220=TAS, GO:0051289=ISS, GO:0070588=ISS, GO:0071277=ISS, GO:0015278=IMP, GO:0006816=IMP, GO:0016021=ISS, GO:0005219=TAS} calcium ion transmembrane transport, calcium ion transport, cellular calcium ion homeostasis, cellular response to ATP, cellular response to caffeine, cellular response to calcium ion, cellular response to magnesium ion, ion transmembrane transport, protein homotetramerization, striated muscle contraction, transmembrane transport integral to membrane, junctional membrane complex, sarcoplasmic reticulum membrane calcium ion binding, calcium-release channel activity, calmodulin binding, ryanodine-sensitive calcium-release channel activity Human S100A1 InterPro UniProtKB {GO:0005515=PMID:16189514, GO:0035556=PMID:12804600, GO:0044548=PMID:10913138, GO:0043234=PMID:14638689, GO:0016529=GO_REF:0000019, GO:0008016=PMID:12804600, GO:0005509=GO_REF:0000002, GO:0051117=PMID:12804600, GO:0005634=PMID:12118070, GO:0000122=GO_REF:0000019, GO:0042803=PMID:10913138, GO:0042802=PMID:21296671} Q5T7Y6 Protein S100-A1 protein 20130413 {GO:0005515=IPI, GO:0035556=NAS, GO:0044548=IPI, GO:0043234=NAS, GO:0016529=IEA, GO:0008016=NAS, GO:0005509=IEA, GO:0051117=IPI, GO:0005634=IDA, GO:0000122=IEA, GO:0042803=IDA, GO:0042802=IPI} intracellular signal transduction, negative regulation of transcription from RNA polymerase II promoter, regulation of heart contraction nucleus, protein complex, sarcoplasmic reticulum ATPase binding, S100 protein binding, calcium ion binding, identical protein binding, protein binding, protein homodimerization activity Human InterPro:IPR001751|InterPro:IPR002048|InterPro:IPR011992 S100A10 PINC UniProtKB {GO:0007165=PMID:1831433, GO:0005509=GO_REF:0000002, GO:0005102=PMID:1831433, GO:0071229=GO_REF:0000019, GO:0051099=GO_REF:0000019, GO:0019897=GO_REF:0000019} P60903 Protein S100-A10 protein 20061108 {GO:0007165=NAS, GO:0005509=IEA, GO:0005102=NAS, GO:0071229=IEA, GO:0051099=IEA, GO:0019897=IEA} cellular response to acid, positive regulation of binding, signal transduction extrinsic to plasma membrane calcium ion binding, receptor binding Human S100A11 HPA UniProtKB {GO:0007165=PMID:16130169, GO:0044548=PMID:10913138, GO:0005737=PMID:16130169, GO:0008285=PMID:10851017, GO:0005509=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008156=PMID:10851017, GO:0001726=PMID:10913138, GO:0042803=PMID:10913138, GO:0048306=PMID:10913138} P31949 Protein S100-A11 protein 20111111 {GO:0007165=TAS, GO:0044548=IPI, GO:0005737=TAS, GO:0008285=TAS, GO:0005509=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008156=TAS, GO:0001726=IDA, GO:0042803=IDA, GO:0048306=IDA} negative regulation of DNA replication, negative regulation of cell proliferation, signal transduction cytoplasm, nucleolus, nucleus, ruffle S100 protein binding, calcium ion binding, calcium-dependent protein binding, protein homodimerization activity NOT Human S100A12 Reactome UniProtKB {GO:0005515=PMID:19386136, GO:0050663=PMID:18443896, GO:0045576=PMID:18443896, GO:0006805=PMID:11522286, GO:0005886=PMID:18443896, GO:0050832=PMID:18443896, GO:0005634=PMID:15033494, GO:0005829=PMID:18443896, GO:0005737=PMID:15033494, GO:0006954=GO_REF:0000037, GO:0051092=PMID:18443896, GO:0050786=PMID:18443896, GO:0043406=PMID:18443896, GO:0031640=GO_REF:0000037, GO:0043123=PMID:15033494, GO:0005856=PMID:18443896, GO:0042742=PMID:18443896, GO:0005507=PMID:18443896, GO:0005509=PMID:18443896, GO:0030593=PMID:18443896, GO:0005576=Reactome:REACT_25382, GO:0002548=PMID:18443896, GO:0045087=Reactome:REACT_6802, GO:0050729=PMID:18443896, GO:0008270=PMID:18443896} P80511 Protein S100-A12 protein 20100617 {GO:0005515=IPI, GO:0050663=TAS, GO:0045576=TAS, GO:0006805=IDA, GO:0005886=TAS, GO:0050832=TAS, GO:0005634=IDA, GO:0005829=TAS, GO:0005737=IDA, GO:0006954=IEA, GO:0051092=TAS, GO:0050786=TAS, GO:0043406=TAS, GO:0031640=IEA, GO:0043123=IDA, GO:0005856=TAS, GO:0042742=TAS, GO:0005507=TAS, GO:0005509=TAS, GO:0030593=TAS, GO:0005576=TAS, GO:0002548=TAS, GO:0045087=TAS, GO:0050729=TAS, GO:0008270=TAS} cytokine secretion, defense response to bacterium, defense response to fungus, inflammatory response, innate immune response, killing of cells of other organism, mast cell activation, monocyte chemotaxis, neutrophil chemotaxis, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of MAP kinase activity, positive regulation of NF-kappaB transcription factor activity, positive regulation of inflammatory response, xenobiotic metabolic process cytoplasm, cytoskeleton, cytosol, extracellular region, nucleus, plasma membrane RAGE receptor binding, calcium ion binding, copper ion binding, protein binding, zinc ion binding Human S100A13 UniProtKB UniProtKB {GO:0005515=PMID:19284995, GO:0008284=GO_REF:0000019, GO:0048471=PMID:10722710, GO:0043303=PMID:10051426, GO:0050663=PMID:20863990, GO:0005507=PMID:16145699, GO:0017134=PMID:11432880, GO:0008360=GO_REF:0000019, GO:0050703=PMID:12746488, GO:0005509=PMID:17374362, GO:0005634=PMID:15033494, GO:0005615=PMID:12746488, GO:0042803=PMID:12746488, GO:0005829=PMID:12746488, GO:0008289=GO_REF:0000037, GO:0005737=PMID:15821778, GO:0050786=PMID:15033494, GO:0051602=GO_REF:0000019, GO:0008270=PMID:12118070, GO:0043123=PMID:15033494, GO:0046688=GO_REF:0000019} Q99584 Protein S100-A13 protein 20091130 {GO:0005515=IPI, GO:0008284=IEA, GO:0048471=IDA, GO:0043303=NAS, GO:0050663=IMP, GO:0005507=IDA, GO:0017134=IPI, GO:0008360=IEA, GO:0050703=IDA, GO:0005509=IDA, GO:0005634=IDA, GO:0005615=IDA, GO:0042803=IPI, GO:0005829=IDA, GO:0008289=IEA, GO:0005737=IDA, GO:0050786=IPI, GO:0051602=IEA, GO:0008270=IDA, GO:0043123=IDA, GO:0046688=IEA} cytokine secretion, interleukin-1 alpha secretion, mast cell degranulation, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of cell proliferation, regulation of cell shape, response to copper ion, response to electrical stimulus cytoplasm, cytosol, extracellular space, nucleus, perinuclear region of cytoplasm RAGE receptor binding, calcium ion binding, copper ion binding, fibroblast growth factor binding, lipid binding, protein binding, protein homodimerization activity, zinc ion binding Human UniProtKB:P21579 S100A14 HPA UniProtKB {GO:0048471=PMID:11944983, GO:0030054=GO_REF:0000052, GO:0034142=PMID:17625598, GO:0005886=GO_REF:0000052, GO:0005509=PMID:16682778, GO:0006915=GO_REF:0000037, GO:0042379=PMID:18606705, GO:0071624=PMID:18606705, GO:0055074=PMID:16682778, GO:0005737=GO_REF:0000052, GO:0015630=GO_REF:0000052, GO:0032496=PMID:17625598, GO:0090026=PMID:18606705, GO:0042742=PMID:17625598} Q9HCY8 Protein S100-A14 protein 20101115 {GO:0048471=IDA, GO:0030054=IDA, GO:0034142=IDA, GO:0005886=IDA, GO:0005509=NAS, GO:0006915=IEA, GO:0042379=IMP, GO:0071624=IDA, GO:0055074=NAS, GO:0005737=IDA, GO:0015630=IDA, GO:0032496=IEP, GO:0090026=IDA, GO:0042742=IEP} apoptotic process, calcium ion homeostasis, defense response to bacterium, positive regulation of granulocyte chemotaxis, positive regulation of monocyte chemotaxis, response to lipopolysaccharide, toll-like receptor 4 signaling pathway cell junction, cytoplasm, microtubule cytoskeleton, perinuclear region of cytoplasm, plasma membrane calcium ion binding, chemokine receptor binding Human S100A16 HPA UniProtKB {GO:0051592=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005509=PMID:17030513, GO:0005730=PMID:17030513, GO:0042803=PMID:17030513, GO:0005829=PMID:17030513} Q96FQ6 Protein S100-A16 protein 20111111 {GO:0051592=IEA, GO:0005737=IDA, GO:0005886=IDA, GO:0005509=IDA, GO:0005730=IDA, GO:0042803=IPI, GO:0005829=IDA} response to calcium ion cytoplasm, cytosol, nucleolus, plasma membrane calcium ion binding, protein homodimerization activity Human S100A2 InterPro UniProtKB {GO:0043542=PMID:15313892, GO:0005509=GO_REF:0000002, GO:0005575=GO_REF:0000015} Q5RHS7 Protein S100-A2 protein 20130413 {GO:0043542=IMP, GO:0005509=IEA, GO:0005575=ND} endothelial cell migration cellular_component calcium ion binding Human InterPro:IPR001751|InterPro:IPR002048|InterPro:IPR011992 S100A3 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005509=GO_REF:0000002} P33764 Protein S100-A3 protein 20130413 {GO:0005737=IEA, GO:0005509=IEA} cytoplasm calcium ion binding Human UniProtKB-SubCell:SL-0086 S100A4 HGNC UniProtKB {GO:0005515=PMID:15479433, GO:0043005=GO_REF:0000019, GO:0048471=PMID:15033494, GO:0050786=PMID:15033494, GO:0005509=GO_REF:0000019, GO:0005634=PMID:15033494, GO:0001837=PMID:14679171, GO:0043123=PMID:15033494, GO:0048306=GO_REF:0000019, GO:0042802=GO_REF:0000019} P26447 Protein S100-A4 protein 20070403 {GO:0005515=IPI, GO:0043005=IEA, GO:0048471=IDA, GO:0050786=IPI, GO:0005509=IEA, GO:0005634=IDA, GO:0001837=TAS, GO:0043123=IDA, GO:0048306=IEA, GO:0042802=IEA} epithelial to mesenchymal transition, positive regulation of I-kappaB kinase/NF-kappaB cascade neuron projection, nucleus, perinuclear region of cytoplasm RAGE receptor binding, calcium ion binding, calcium-dependent protein binding, identical protein binding, protein binding Human S100A5 InterPro UniProtKB {GO:0005507=PMID:19536568, GO:0005509=GO_REF:0000002, GO:0008270=PMID:19536568, GO:0005634=PMID:12118070, GO:0042803=PMID:19536568} Q52LE7 S100 calcium binding protein A5, isoform CRA_b protein 20130413 {GO:0005507=IDA, GO:0005509=IEA, GO:0008270=IDA, GO:0005634=IDA, GO:0042803=IPI} nucleus calcium ion binding, copper ion binding, protein homodimerization activity, zinc ion binding Human InterPro:IPR001751|InterPro:IPR002048|InterPro:IPR011992 S100A6 HPA UniProtKB {GO:0005515=PMID:19724273, GO:0048471=PMID:12118070, GO:0015075=GO_REF:0000019, GO:0005509=PMID:11937060, GO:0005634=PMID:10913138, GO:0048146=PMID:12577318, GO:0005635=PMID:12805373, GO:0007409=PMID:12152788, GO:0001726=PMID:10913138, GO:0042803=PMID:11937060, GO:0031234=PMID:19724273, GO:0005829=PMID:19724273, GO:0044548=PMID:10913138, GO:0007165=PMID:16130169, GO:0005737=GO_REF:0000052, GO:0008270=GO_REF:0000019, GO:0005523=PMID:19724273, GO:0048306=PMID:10913138} P06703 Protein S100-A6 protein 20080205 {GO:0005515=IPI, GO:0048471=IDA, GO:0015075=IEA, GO:0005509=IDA, GO:0005634=IDA, GO:0048146=NAS, GO:0005635=IDA, GO:0007409=NAS, GO:0001726=IDA, GO:0042803=IPI, GO:0031234=IDA, GO:0005829=IDA, GO:0044548=IPI, GO:0007165=TAS, GO:0005737=IDA, GO:0008270=IEA, GO:0005523=IDA, GO:0048306=IDA} axonogenesis, positive regulation of fibroblast proliferation, signal transduction cytoplasm, cytosol, extrinsic to internal side of plasma membrane, nuclear envelope, nucleus, perinuclear region of cytoplasm, ruffle S100 protein binding, calcium ion binding, calcium-dependent protein binding, ion transmembrane transporter activity, protein binding, protein homodimerization activity, tropomyosin binding, zinc ion binding Human S100A7 IntAct UniProtKB {GO:0005515=PMID:12421467, GO:0051238=PMID:15568027, GO:0005783=PMID:12839573, GO:0010820=PMID:18606705, GO:0005509=PMID:8077703, GO:0005576=PMID:9693957, GO:0005634=PMID:10595935, GO:0001525=PMID:16357139, GO:0071624=PMID:18606705, GO:0005829=PMID:12839573, GO:0050829=PMID:15568027, GO:0005737=PMID:9693957, GO:0008544=PMID:1940442, GO:0050786=PMID:18606705, GO:0030216=PMID:15740587, GO:0045087=PMID:15568027, GO:0032496=PMID:17625598, GO:0008270=PMID:10026247, GO:0070374=PMID:18606705, GO:0090026=PMID:18606705, GO:0005925=PMID:12839573, GO:0000302=PMID:16082188} P31151 Protein S100-A7 protein 20130415 {GO:0005515=IPI, GO:0051238=IDA, GO:0005783=IDA, GO:0010820=IDA, GO:0005509=IDA, GO:0005576=TAS, GO:0005634=IDA, GO:0001525=NAS, GO:0071624=IDA, GO:0005829=IDA, GO:0050829=IMP, GO:0005737=TAS, GO:0008544=TAS, GO:0050786=IPI, GO:0030216=NAS, GO:0045087=NAS, GO:0032496=IEP, GO:0008270=NAS, GO:0070374=IDA, GO:0090026=IDA, GO:0005925=NAS, GO:0000302=IDA} angiogenesis, defense response to Gram-negative bacterium, epidermis development, innate immune response, keratinocyte differentiation, positive regulation of ERK1 and ERK2 cascade, positive regulation of T cell chemotaxis, positive regulation of granulocyte chemotaxis, positive regulation of monocyte chemotaxis, response to lipopolysaccharide, response to reactive oxygen species, sequestering of metal ion cytoplasm, cytosol, endoplasmic reticulum, extracellular region, focal adhesion, nucleus RAGE receptor binding, calcium ion binding, protein binding, zinc ion binding Human UniProtKB:Q96S59 S100A8 IntAct UniProtKB {GO:0005515=PMID:20936779, GO:0008017=PMID:22489132, GO:0035662=PMID:22489132, GO:0005886=PMID:22489132, GO:0050544=PMID:22489132, GO:0030307=PMID:22489132, GO:0045471=GO_REF:0000019, GO:0050832=PMID:22489132, GO:0001816=PMID:22489132, GO:0010043=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0005829=PMID:22489132, GO:0006954=PMID:3313057, GO:0051092=PMID:22489132, GO:0050786=PMID:22489132, GO:0032602=PMID:22489132, GO:0032496=GO_REF:0000019, GO:0005856=PMID:22489132, GO:0042742=PMID:22489132, GO:0002526=GO_REF:0000019, GO:0006919=PMID:19935772, GO:0002523=PMID:12626582, GO:0032119=PMID:22489132, GO:0005509=PMID:22489132, GO:0030593=PMID:12626582, GO:0006914=PMID:19935772, GO:0005576=PMID:22489132, GO:0006917=PMID:19935772, GO:0002544=GO_REF:0000019, GO:0051493=PMID:22489132, GO:0045087=GO_REF:0000037, GO:0050729=PMID:12626582, GO:0042060=GO_REF:0000019, GO:0070488=PMID:12626582, GO:0008270=PMID:22489132} P05109 Protein S100-A8 protein 20130415 {GO:0005515=IPI, GO:0008017=TAS, GO:0035662=TAS, GO:0005886=TAS, GO:0050544=TAS, GO:0030307=TAS, GO:0045471=IEA, GO:0050832=TAS, GO:0001816=TAS, GO:0010043=IEA, GO:0005615=IEA, GO:0005829=TAS, GO:0006954=TAS, GO:0051092=TAS, GO:0050786=TAS, GO:0032602=TAS, GO:0032496=IEA, GO:0005856=TAS, GO:0042742=TAS, GO:0002526=IEA, GO:0006919=IDA, GO:0002523=IDA, GO:0032119=TAS, GO:0005509=TAS, GO:0030593=IDA, GO:0006914=IDA, GO:0005576=TAS, GO:0006917=IDA, GO:0002544=IEA, GO:0051493=TAS, GO:0045087=IEA, GO:0050729=IDA, GO:0042060=IEA, GO:0070488=IDA, GO:0008270=TAS} activation of cysteine-type endopeptidase activity involved in apoptotic process, acute inflammatory response, autophagy, chemokine production, chronic inflammatory response, cytokine production, defense response to bacterium, defense response to fungus, induction of apoptosis, inflammatory response, innate immune response, leukocyte migration involved in inflammatory response, neutrophil aggregation, neutrophil chemotaxis, positive regulation of NF-kappaB transcription factor activity, positive regulation of cell growth, positive regulation of inflammatory response, regulation of cytoskeleton organization, response to ethanol, response to lipopolysaccharide, response to zinc ion, sequestering of zinc ion, wound healing cytoskeleton, cytosol, extracellular region, extracellular space, plasma membrane RAGE receptor binding, Toll-like receptor 4 binding, arachidonic acid binding, calcium ion binding, microtubule binding, protein binding, zinc ion binding Human UniProtKB:P06702 S100A9 GOC UniProtKB {GO:0005515=PMID:20936779, GO:0008017=PMID:22489132, GO:0035662=PMID:22489132, GO:0005886=PMID:22489132, GO:0050544=PMID:22489132, GO:0030307=PMID:22489132, GO:0045471=GO_REF:0000019, GO:0050832=PMID:22489132, GO:0007267=PMID:3313057, GO:0005634=GO_REF:0000052, GO:0001816=PMID:22489132, GO:0010043=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0005829=PMID:22489132, GO:0005737=GO_REF:0000052, GO:0006954=PMID:3313057, GO:0051092=PMID:22489132, GO:0050786=PMID:22489132, GO:0032602=PMID:22489132, GO:0032496=GO_REF:0000019, GO:0004871=PMID:3313057, GO:0005856=PMID:22489132, GO:0042742=PMID:22489132, GO:0016209=GO_REF:0000037, GO:0031532=GO_REF:0000019, GO:0006919=PMID:19935772, GO:0002523=PMID:12626582, GO:0045113=GO_REF:0000019, GO:0032119=PMID:22489132, GO:0030593=PMID:12626582, GO:0005509=PMID:22489132, GO:0005730=GO_REF:0000052, GO:0006914=PMID:19935772, GO:0005576=PMID:22489132, GO:0006917=PMID:19935772, GO:0002544=GO_REF:0000019, GO:0007165=PMID:3313057, GO:0051493=PMID:22489132, GO:0045087=GO_REF:0000037, GO:0050729=PMID:12626582, GO:0070488=PMID:12626582, GO:0008270=PMID:22489132} P06702 Protein S100-A9 protein 20130413 {GO:0005515=IPI, GO:0008017=TAS, GO:0035662=TAS, GO:0005886=TAS, GO:0050544=TAS, GO:0030307=TAS, GO:0045471=IEA, GO:0050832=TAS, GO:0007267=TAS, GO:0005634=IDA, GO:0001816=TAS, GO:0010043=IEA, GO:0005615=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0006954=TAS, GO:0051092=TAS, GO:0050786=TAS, GO:0032602=TAS, GO:0032496=IEA, GO:0004871=TAS, GO:0005856=TAS, GO:0042742=TAS, GO:0016209=IEA, GO:0031532=IEA, GO:0006919=IDA, GO:0002523=IDA, GO:0045113=IEA, GO:0032119=TAS, GO:0030593=IDA, GO:0005509=TAS, GO:0005730=IDA, GO:0006914=IDA, GO:0005576=TAS, GO:0006917=IDA, GO:0002544=IEA, GO:0007165=TAS, GO:0051493=TAS, GO:0045087=IEA, GO:0050729=IDA, GO:0070488=IDA, GO:0008270=TAS} actin cytoskeleton reorganization, activation of cysteine-type endopeptidase activity involved in apoptotic process, autophagy, cell-cell signaling, chemokine production, chronic inflammatory response, cytokine production, defense response to bacterium, defense response to fungus, induction of apoptosis, inflammatory response, innate immune response, leukocyte migration involved in inflammatory response, neutrophil aggregation, neutrophil chemotaxis, positive regulation of NF-kappaB transcription factor activity, positive regulation of cell growth, positive regulation of inflammatory response, regulation of cytoskeleton organization, regulation of integrin biosynthetic process, response to ethanol, response to lipopolysaccharide, response to zinc ion, sequestering of zinc ion, signal transduction cytoplasm, cytoskeleton, cytosol, extracellular region, extracellular space, nucleolus, nucleus, plasma membrane RAGE receptor binding, Toll-like receptor 4 binding, antioxidant activity, arachidonic acid binding, calcium ion binding, microtubule binding, protein binding, signal transducer activity, zinc ion binding Human S100B IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0008284=GO_REF:0000019, GO:0048471=PMID:15033494, GO:0008283=PMID:8202493, GO:0048708=GO_REF:0000019, GO:0008360=GO_REF:0000019, GO:0060291=GO_REF:0000019, GO:0005634=PMID:10913138, GO:0007409=PMID:8202493, GO:0005615=GO_REF:0000019, GO:0042803=PMID:9519411, GO:0042802=PMID:10913138, GO:0005737=PMID:10913138, GO:0050786=PMID:15033494, GO:0048168=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0007611=GO_REF:0000024, GO:0007613=GO_REF:0000019, GO:2001015=GO_REF:0000019, GO:0043123=PMID:15033494, GO:0043065=GO_REF:0000019, GO:0005509=PMID:9519411, GO:0048156=GO_REF:0000024, GO:0071456=GO_REF:0000019, GO:0005576=Reactome:REACT_115713, GO:0051384=GO_REF:0000019, GO:0007417=PMID:8202493, GO:0001726=PMID:10913138, GO:0044548=PMID:9519411, GO:0051597=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0008270=GO_REF:0000024, GO:0048306=PMID:10913138} P04271 Protein S100-B protein 20130415 {GO:0005515=IPI, GO:0008284=IEA, GO:0048471=IDA, GO:0008283=TAS, GO:0048708=IEA, GO:0008360=IEA, GO:0060291=IEA, GO:0005634=IDA, GO:0007409=TAS, GO:0005615=IEA, GO:0042803=IPI, GO:0042802=IPI, GO:0005737=IDA, GO:0050786=IPI, GO:0048168=IEA, GO:0043025=IEA, GO:0007611=ISS, GO:0007613=IEA, GO:2001015=IEA, GO:0043123=IDA, GO:0043065=IEA, GO:0005509=NAS, GO:0048156=ISS, GO:0071456=IEA, GO:0005576=TAS, GO:0051384=IEA, GO:0007417=TAS, GO:0001726=IDA, GO:0044548=IPI, GO:0051597=IEA, GO:0045087=TAS, GO:0008270=ISS, GO:0048306=IDA} astrocyte differentiation, axonogenesis, cell proliferation, cellular response to hypoxia, central nervous system development, innate immune response, learning or memory, long-term synaptic potentiation, memory, negative regulation of skeletal muscle cell differentiation, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of apoptotic process, positive regulation of cell proliferation, regulation of cell shape, regulation of neuronal synaptic plasticity, response to glucocorticoid stimulus, response to methylmercury cytoplasm, extracellular region, extracellular space, neuronal cell body, nucleus, perinuclear region of cytoplasm, ruffle RAGE receptor binding, S100 protein binding, calcium ion binding, calcium-dependent protein binding, identical protein binding, protein binding, protein homodimerization activity, tau protein binding, zinc ion binding Human UniProtKB:P04271 S100P HPA UniProtKB {GO:0005515=PMID:16189514, GO:0005737=GO_REF:0000052, GO:0000287=PMID:15632002, GO:0043542=PMID:15313892, GO:0005509=GO_REF:0000002, GO:0005634=PMID:15632002, GO:0048306=PMID:15632002} P25815 Protein S100-P protein 20101115 {GO:0005515=IPI, GO:0005737=IDA, GO:0000287=TAS, GO:0043542=IMP, GO:0005509=IEA, GO:0005634=IDA, GO:0048306=IPI} endothelial cell migration cytoplasm, nucleus calcium ion binding, calcium-dependent protein binding, magnesium ion binding, protein binding Human S100PBP HGNC UniProtKB {GO:0005634=PMID:15632002, GO:0048306=PMID:15632002} Q96BU1 S100P-binding protein protein 20050720 {GO:0005634=IDA, GO:0048306=IPI} nucleus calcium-dependent protein binding Human UniProtKB:P25815 S100Z InterPro UniProtKB {GO:0005509=GO_REF:0000002} Q8WXG8 Protein S100-Z protein 20130413 {GO:0005509=IEA} calcium ion binding Human InterPro:IPR001751|InterPro:IPR002048|InterPro:IPR011992 S1PR1 Reactome UniProtKB {GO:0030335=GO_REF:0000019, GO:0005886=Reactome:REACT_22289, GO:0046625=GO_REF:0000019, GO:0004930=PMID:8626678, GO:0001525=GO_REF:0000019, GO:0019226=GO_REF:0000019, GO:0048661=GO_REF:0000019, GO:0038036=GO_REF:0000002, GO:0007193=GO_REF:0000019, GO:0030155=GO_REF:0000019, GO:0050927=GO_REF:0000019, GO:0051497=GO_REF:0000019, GO:0007186=PMID:8626678, GO:0032320=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0030182=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0051482=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0045446=GO_REF:0000019, GO:0007155=PMID:10555146, GO:0009897=GO_REF:0000019} P21453 Sphingosine 1-phosphate receptor 1 protein 20090430 {GO:0030335=IEA, GO:0005886=TAS, GO:0046625=IEA, GO:0004930=TAS, GO:0001525=IEA, GO:0019226=IEA, GO:0048661=IEA, GO:0038036=IEA, GO:0007193=IEA, GO:0030155=IEA, GO:0050927=IEA, GO:0051497=IEA, GO:0007186=TAS, GO:0032320=IEA, GO:0007420=IEA, GO:0030182=IEA, GO:0045944=IEA, GO:0051482=IEA, GO:0016021=IEA, GO:0045446=IEA, GO:0007155=TAS, GO:0009897=IEA} G-protein coupled receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, angiogenesis, brain development, cell adhesion, elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway, endothelial cell differentiation, negative regulation of stress fiber assembly, neuron differentiation, positive regulation of Ras GTPase activity, positive regulation of cell migration, positive regulation of positive chemotaxis, positive regulation of smooth muscle cell proliferation, positive regulation of transcription from RNA polymerase II promoter, regulation of cell adhesion, transmission of nerve impulse external side of plasma membrane, integral to membrane, plasma membrane G-protein coupled receptor activity, sphingolipid binding, sphingosine-1-phosphate receptor activity Human S1PR2 Reactome UniProtKB {GO:0000187=PMID:10617617, GO:0008284=PMID:10617617, GO:0005886=Reactome:REACT_22289, GO:0007186=PMID:10617617, GO:0004930=PMID:8087418, GO:0007610=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0038036=GO_REF:0000002, GO:0008289=PMID:10617617} O95136 Sphingosine 1-phosphate receptor 2 protein 20090430 {GO:0000187=TAS, GO:0008284=TAS, GO:0005886=TAS, GO:0007186=TAS, GO:0004930=TAS, GO:0007610=IEA, GO:0016021=IEA, GO:0038036=IEA, GO:0008289=TAS} G-protein coupled receptor signaling pathway, activation of MAPK activity, behavior, positive regulation of cell proliferation integral to membrane, plasma membrane G-protein coupled receptor activity, lipid binding, sphingosine-1-phosphate receptor activity Human S1PR3 Reactome UniProtKB {GO:0008284=PMID:10617617, GO:0005886=Reactome:REACT_22289, GO:0004930=PMID:10555146, GO:0001816=GO_REF:0000019, GO:0038036=GO_REF:0000002, GO:0007193=GO_REF:0000019, GO:0007204=PMID:9409733, GO:0009653=PMID:10555146, GO:0008289=PMID:9409733, GO:0006954=GO_REF:0000019, GO:0007186=PMID:10617617, GO:0005887=PMID:9409733, GO:0032651=GO_REF:0000019} Q99500 Sphingosine 1-phosphate receptor 3 protein 20090430 {GO:0008284=TAS, GO:0005886=TAS, GO:0004930=TAS, GO:0001816=IEA, GO:0038036=IEA, GO:0007193=IEA, GO:0007204=TAS, GO:0009653=TAS, GO:0008289=TAS, GO:0006954=IEA, GO:0007186=TAS, GO:0005887=TAS, GO:0032651=IEA} G-protein coupled receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, anatomical structure morphogenesis, cytokine production, elevation of cytosolic calcium ion concentration, inflammatory response, positive regulation of cell proliferation, regulation of interleukin-1 beta production integral to plasma membrane, plasma membrane G-protein coupled receptor activity, lipid binding, sphingosine-1-phosphate receptor activity Human S1PR4 Reactome UniProtKB {GO:0006955=PMID:9790765, GO:0005886=Reactome:REACT_22289, GO:0007186=PMID:9790765, GO:0005887=PMID:9790765, GO:0004930=PMID:10679247, GO:0007202=PMID:10679247, GO:0007189=GO_REF:0000019, GO:0007204=PMID:10679247, GO:0038036=GO_REF:0000002, GO:0008289=PMID:10679247} O95977 Sphingosine 1-phosphate receptor 4 protein 20090430 {GO:0006955=TAS, GO:0005886=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0004930=TAS, GO:0007202=TAS, GO:0007189=IEA, GO:0007204=TAS, GO:0038036=IEA, GO:0008289=TAS} G-protein coupled receptor signaling pathway, activation of phospholipase C activity, adenylate cyclase-activating G-protein coupled receptor signaling pathway, elevation of cytosolic calcium ion concentration, immune response integral to plasma membrane, plasma membrane G-protein coupled receptor activity, lipid binding, sphingosine-1-phosphate receptor activity Human S1PR5 Reactome UniProtKB {GO:0005886=Reactome:REACT_22289, GO:0045664=GO_REF:0000019, GO:0016021=GO_REF:0000019, GO:0038036=GO_REF:0000002} Q9H228 Sphingosine 1-phosphate receptor 5 protein 20090430 {GO:0005886=TAS, GO:0045664=IEA, GO:0016021=IEA, GO:0038036=IEA} regulation of neuron differentiation integral to membrane, plasma membrane sphingosine-1-phosphate receptor activity Human SAA1 Reactome UniProtKB {GO:0001664=PMID:9892621, GO:0030593=PMID:12557751, GO:0030168=PMID:1697614, GO:0005576=Reactome:REACT_75905, GO:0050716=PMID:12857601, GO:0006953=PMID:9815279, GO:0050715=PMID:12857601, GO:0007204=PMID:7561109, GO:0045785=PMID:11830469, GO:0034364=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0050728=PMID:9823935, GO:0050708=PMID:9605178, GO:0048247=PMID:7636186, GO:0048246=PMID:7561109} P0DJI8 Serum amyloid A-1 protein protein 20130301 {GO:0001664=IDA, GO:0030593=NAS, GO:0030168=NAS, GO:0005576=TAS, GO:0050716=NAS, GO:0006953=NAS, GO:0050715=IDA, GO:0007204=NAS, GO:0045785=IDA, GO:0034364=IEA, GO:0045087=TAS, GO:0050728=NAS, GO:0050708=NAS, GO:0048247=IDA, GO:0048246=IDA} acute-phase response, elevation of cytosolic calcium ion concentration, innate immune response, lymphocyte chemotaxis, macrophage chemotaxis, negative regulation of inflammatory response, neutrophil chemotaxis, platelet activation, positive regulation of cell adhesion, positive regulation of cytokine secretion, positive regulation of interleukin-1 secretion, regulation of protein secretion extracellular region, high-density lipoprotein particle G-protein coupled receptor binding Human SAA2 UniProtKB UniProtKB {GO:0034364=GO_REF:0000037, GO:0006953=GO_REF:0000037} P0DJI9 Serum amyloid A-2 protein protein 20130413 {GO:0034364=IEA, GO:0006953=IEA} acute-phase response high-density lipoprotein particle Human UniProtKB-KW:KW-0345 SAA4 UniProtKB UniProtKB {GO:0034364=GO_REF:0000037, GO:0005576=PMID:14718574, GO:0006953=GO_REF:0000037} P35542 Serum amyloid A-4 protein protein 20040422 {GO:0034364=IEA, GO:0005576=NAS, GO:0006953=IEA} acute-phase response extracellular region, high-density lipoprotein particle Human SAAL1 InterPro UniProtKB {GO:0005576=GO_REF:0000002, GO:0006953=GO_REF:0000002} Q96ER3 Protein SAAL1 protein 20130413 {GO:0005576=IEA, GO:0006953=IEA} acute-phase response extracellular region Human InterPro:IPR000096 SAC3D1 ENSEMBL UniProtKB {GO:0005515=PMID:16239144, GO:0051298=GO_REF:0000019, GO:0005813=GO_REF:0000019, GO:0007067=GO_REF:0000037, GO:0005737=GO_REF:0000037, GO:0005819=GO_REF:0000019, GO:0051225=GO_REF:0000019, GO:0051301=GO_REF:0000037} F8WC89 SAC3 domain-containing protein 1 protein 20130413 {GO:0005515=IPI, GO:0051298=IEA, GO:0005813=IEA, GO:0007067=IEA, GO:0005737=IEA, GO:0005819=IEA, GO:0051225=IEA, GO:0051301=IEA} cell division, centrosome duplication, mitosis, spindle assembly centrosome, cytoplasm, spindle protein binding Human Ensembl:ENSMUSP00000109161 SACM1L Reactome UniProtKB {GO:0005794=GO_REF:0000054, GO:0006661=Reactome:REACT_121168, GO:0043812=GO_REF:0000019, GO:0030176=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0034593=GO_REF:0000019, GO:0042578=GO_REF:0000002, GO:0016791=GO_REF:0000024, GO:0008150=GO_REF:0000015, GO:0000139=Reactome:REACT_121034, GO:0004438=GO_REF:0000019, GO:0046856=GO_REF:0000019, GO:0005789=Reactome:REACT_121134, GO:0006644=Reactome:REACT_121175} Q9NTJ5 Phosphatidylinositide phosphatase SAC1 protein 20130301 {GO:0005794=IDA, GO:0006661=TAS, GO:0043812=IEA, GO:0030176=IEA, GO:0044281=TAS, GO:0034593=IEA, GO:0042578=IEA, GO:0016791=ISS, GO:0008150=ND, GO:0000139=TAS, GO:0004438=IEA, GO:0046856=IEA, GO:0005789=TAS, GO:0006644=TAS} biological_process, phosphatidylinositol biosynthetic process, phosphatidylinositol dephosphorylation, phospholipid metabolic process, small molecule metabolic process Golgi apparatus, Golgi membrane, endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane phosphatase activity, phosphatidylinositol bisphosphate phosphatase activity, phosphatidylinositol-3-phosphatase activity, phosphatidylinositol-4-phosphate phosphatase activity, phosphoric ester hydrolase activity Human SACS BHF-UCL UniProtKB {GO:0008219=GO_REF:0000037, GO:0030424=PMID:19208651, GO:0090084=PMID:19208651, GO:0051087=PMID:19208651, GO:0005634=PMID:19208651, GO:0005524=GO_REF:0000002, GO:0030425=PMID:19208651, GO:0070852=PMID:19208651, GO:0005739=PMID:19208651, GO:0005737=PMID:19208651, GO:0006457=PMID:10655055, GO:0070628=PMID:19208651, GO:0030544=PMID:19208651} Q9NZJ4 Sacsin protein 20091209 {GO:0008219=IEA, GO:0030424=TAS, GO:0090084=IMP, GO:0051087=IDA, GO:0005634=IDA, GO:0005524=IEA, GO:0030425=TAS, GO:0070852=TAS, GO:0005739=IDA, GO:0005737=IDA, GO:0006457=NAS, GO:0070628=IPI, GO:0030544=IPI} cell death, negative regulation of inclusion body assembly, protein folding axon, cell body fiber, cytoplasm, dendrite, mitochondrion, nucleus ATP binding, Hsp70 protein binding, chaperone binding, proteasome binding Human SAE1 HPA UniProtKB {GO:0005515=PMID:16189514, GO:0043008=PMID:10187858, GO:0016567=PMID:10187858, GO:0046982=PMID:20164921, GO:0016874=GO_REF:0000037, GO:0016925=PMID:20164921, GO:0005730=GO_REF:0000052, GO:0004839=PMID:10187858, GO:0005634=GO_REF:0000052, GO:0008641=GO_REF:0000002, GO:0043085=PMID:9920803, GO:0003824=GO_REF:0000002, GO:0008022=PMID:10187858, GO:0019948=PMID:20164921, GO:0043231=GO_REF:0000052, GO:0008047=PMID:9920803, GO:0006464=GO_REF:0000002} Q9UBE0 SUMO-activating enzyme subunit 1 protein 20111111 {GO:0005515=IPI, GO:0043008=IDA, GO:0016567=TAS, GO:0046982=IPI, GO:0016874=IEA, GO:0016925=IDA, GO:0005730=IDA, GO:0004839=TAS, GO:0005634=IDA, GO:0008641=IEA, GO:0043085=TAS, GO:0003824=IEA, GO:0008022=IDA, GO:0019948=IDA, GO:0043231=IDA, GO:0008047=TAS, GO:0006464=IEA} cellular protein modification process, positive regulation of catalytic activity, protein sumoylation, protein ubiquitination intracellular membrane-bounded organelle, nucleolus, nucleus ATP-dependent protein binding, SUMO activating enzyme activity, catalytic activity, enzyme activator activity, ligase activity, protein C-terminus binding, protein binding, protein heterodimerization activity, small protein activating enzyme activity, ubiquitin activating enzyme activity Human SAFB HPA UniProtKB {GO:0005515=PMID:14559993, GO:0003723=GO_REF:0000037, GO:0006325=PMID:1324173, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0001047=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0003690=PMID:1324173, GO:0000166=GO_REF:0000002, GO:0003682=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0042445=GO_REF:0000019, GO:0040007=GO_REF:0000019, GO:0030520=GO_REF:0000019} Q15424 Scaffold attachment factor B1 protein 20090616 {GO:0005515=IPI, GO:0003723=IEA, GO:0006325=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0001047=IEA, GO:0003676=IEA, GO:0006351=IEA, GO:0003690=TAS, GO:0000166=IEA, GO:0003682=IEA, GO:0045944=IEA, GO:0042445=IEA, GO:0040007=IEA, GO:0030520=IEA} chromatin organization, growth, hormone metabolic process, intracellular estrogen receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleolus, nucleus RNA binding, chromatin binding, core promoter binding, double-stranded DNA binding, nucleic acid binding, nucleotide binding, protein binding NOT Human SAFB2 IntAct UniProtKB {GO:0005515=PMID:20562859, GO:0005737=GO_REF:0000039, GO:0006355=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q14151 Scaffold attachment factor B2 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0006355=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus DNA binding, RNA binding, nucleic acid binding, nucleotide binding, protein binding Human UniProtKB:Q9H0R8 SAG PINC UniProtKB {GO:0051219=GO_REF:0000019, GO:0001917=GO_REF:0000019, GO:0007165=GO_REF:0000002, GO:0004864=PMID:2550422, GO:0002046=GO_REF:0000019, GO:0007601=GO_REF:0000037, GO:0007166=PMID:7670478, GO:0016056=PMID:2550422, GO:0001750=GO_REF:0000019} P10523 S-arrestin protein 20030904 {GO:0051219=IEA, GO:0001917=IEA, GO:0007165=IEA, GO:0004864=TAS, GO:0002046=IEA, GO:0007601=IEA, GO:0007166=TAS, GO:0016056=TAS, GO:0001750=IEA} cell surface receptor signaling pathway, rhodopsin mediated signaling pathway, signal transduction, visual perception photoreceptor inner segment, photoreceptor outer segment opsin binding, phosphoprotein binding, protein phosphatase inhibitor activity Human SALL1 GOC UniProtKB {GO:0005515=PMID:18297069, GO:0035137=GO_REF:0000019, GO:0000792=PMID:15158448, GO:0008406=PMID:11511981, GO:0001657=GO_REF:0000024, GO:0035136=GO_REF:0000019, GO:0001658=GO_REF:0000024, GO:0003700=PMID:9425907, GO:0031129=GO_REF:0000024, GO:0021553=GO_REF:0000024, GO:0030325=PMID:12065233, GO:0008013=PMID:15158448, GO:0021983=PMID:12065233, GO:0030177=PMID:15158448, GO:0005634=PMID:16443351, GO:0003281=GO_REF:0000024, GO:0045879=GO_REF:0000019, GO:0007507=PMID:11484202, GO:0021772=GO_REF:0000019, GO:0016581=GO_REF:0000024, GO:0045944=PMID:15158448, GO:0004407=GO_REF:0000024, GO:0042473=PMID:9425907, GO:2000177=GO_REF:0000019, GO:0016575=GO_REF:0000024, GO:0010369=PMID:16443351, GO:0001822=PMID:16971658, GO:0001843=GO_REF:0000019, GO:0000122=PMID:16443351, GO:0048566=PMID:18280297, GO:0003677=PMID:9425907, GO:0006351=GO_REF:0000037, GO:0072092=GO_REF:0000024, GO:0003337=PMID:11511981, GO:0045666=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0072073=GO_REF:0000024, GO:0021889=GO_REF:0000024, GO:0060173=PMID:18470945, GO:0008270=GO_REF:0000002, GO:0061034=PMID:18024993, GO:0045893=PMID:15158448, GO:0045892=PMID:16443351, GO:0042733=PMID:9425907} Q9NSC2 Sal-like protein 1 protein 20130413 {GO:0005515=IPI, GO:0035137=IEA, GO:0000792=IDA, GO:0008406=IEP, GO:0001657=ISS, GO:0035136=IEA, GO:0001658=ISS, GO:0003700=NAS, GO:0031129=ISS, GO:0021553=ISS, GO:0030325=IEP, GO:0008013=IDA, GO:0021983=IEP, GO:0030177=IDA, GO:0005634=IDA, GO:0003281=ISS, GO:0045879=IEA, GO:0007507=IMP, GO:0021772=IEA, GO:0016581=ISS, GO:0045944=IDA, GO:0004407=ISS, GO:0042473=IMP, GO:2000177=IEA, GO:0016575=ISS, GO:0010369=IDA, GO:0001822=IMP, GO:0001843=IEA, GO:0000122=IDA, GO:0048566=IMP, GO:0003677=NAS, GO:0006351=IEA, GO:0072092=ISS, GO:0003337=IEP, GO:0045666=IEA, GO:0003682=IEA, GO:0072073=ISS, GO:0021889=ISS, GO:0060173=IMP, GO:0008270=IEA, GO:0061034=IMP, GO:0045893=IDA, GO:0045892=IDA, GO:0042733=IMP} adrenal gland development, branching involved in ureteric bud morphogenesis, embryonic digestive tract development, embryonic digit morphogenesis, forelimb morphogenesis, gonad development, heart development, hindlimb morphogenesis, histone deacetylation, inductive cell-cell signaling, kidney development, kidney epithelium development, limb development, mesenchymal to epithelial transition involved in metanephros morphogenesis, negative regulation of smoothened signaling pathway, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, neural tube closure, olfactory bulb development, olfactory bulb interneuron differentiation, olfactory bulb mitral cell layer development, olfactory nerve development, outer ear morphogenesis, pituitary gland development, positive regulation of Wnt receptor signaling pathway, positive regulation of neuron differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of neural precursor cell proliferation, transcription, DNA-dependent, ureteric bud development, ureteric bud invasion, ventricular septum development NuRD complex, chromocenter, heterochromatin, nucleus DNA binding, beta-catenin binding, chromatin binding, histone deacetylase activity, protein binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB:Q9ER74 SALL2 UniProtKB UniProtKB {GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000029, GO:0016581=GO_REF:0000019, GO:0021915=GO_REF:0000019, GO:0005634=GO_REF:0000029, GO:0008270=GO_REF:0000002, GO:0000122=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000029, GO:0006351=GO_REF:0000037} Q9Y467 Sal-like protein 2 protein 20021101 {GO:0006355=NAS, GO:0003700=NAS, GO:0016581=IEA, GO:0021915=IEA, GO:0005634=NAS, GO:0008270=IEA, GO:0000122=IEA, GO:0003676=IEA, GO:0003677=NAS, GO:0006351=IEA} negative regulation of transcription from RNA polymerase II promoter, neural tube development, regulation of transcription, DNA-dependent, transcription, DNA-dependent NuRD complex, nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human SALL3 UniProtKB UniProtKB {GO:0035137=GO_REF:0000019, GO:0035136=GO_REF:0000019, GO:0021891=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0045879=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9BXA9 Sal-like protein 3 protein 20130413 {GO:0035137=IEA, GO:0035136=IEA, GO:0021891=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0045879=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} forelimb morphogenesis, hindlimb morphogenesis, negative regulation of smoothened signaling pathway, olfactory bulb interneuron development, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 SALL4 UniProtKB UniProtKB {GO:0000792=GO_REF:0000019, GO:0001833=GO_REF:0000019, GO:0001843=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0003281=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0030326=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0043234=GO_REF:0000019, GO:0019827=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0008270=GO_REF:0000002} Q9UJQ4 Sal-like protein 4 protein 20130413 {GO:0000792=IEA, GO:0001833=IEA, GO:0001843=IEA, GO:0005634=IEA, GO:0003281=IEA, GO:0000122=IEA, GO:0030326=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0043234=IEA, GO:0019827=IEA, GO:0045944=IEA, GO:0008270=IEA} embryonic limb morphogenesis, inner cell mass cell proliferation, negative regulation of transcription from RNA polymerase II promoter, neural tube closure, positive regulation of transcription from RNA polymerase II promoter, stem cell maintenance, transcription, DNA-dependent, ventricular septum development heterochromatin, nucleus, protein complex DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 SAMD1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005576=GO_REF:0000039} Q6SPF0 Atherin protein 20130413 {GO:0005737=IEA, GO:0005576=IEA} cytoplasm, extracellular region Human UniProtKB-SubCell:SL-0086 SAMD3 null null {} null null null null {} null null null SAMD4A GOC UniProtKB {GO:0017148=PMID:16221671, GO:0005737=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0045202=GO_REF:0000037, GO:0045727=PMID:16221671, GO:0030371=PMID:16221671, GO:0030425=GO_REF:0000039} Q9UPU9 Protein Smaug homolog 1 protein 20130413 {GO:0017148=IDA, GO:0005737=IEA, GO:0030054=IEA, GO:0045202=IEA, GO:0045727=IDA, GO:0030371=IDA, GO:0030425=IEA} negative regulation of translation, positive regulation of translation cell junction, cytoplasm, dendrite, synapse translation repressor activity Human SAMD4B UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q5PRF9 Protein Smaug homolog 2 protein 20130413 {GO:0005737=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 SAMD8 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:2000303=PMID:19506037, GO:0006686=PMID:14685263, GO:0030176=PMID:19506037, GO:0016021=PMID:14685263, GO:0046513=PMID:19506037, GO:0016740=GO_REF:0000037} Q96LT4 Sphingomyelin synthase-related protein 1 protein 20120831 {GO:0003674=ND, GO:2000303=IDA, GO:0006686=NAS, GO:0030176=IDA, GO:0016021=NAS, GO:0046513=IDA, GO:0016740=IEA} ceramide biosynthetic process, regulation of ceramide biosynthetic process, sphingomyelin biosynthetic process integral to endoplasmic reticulum membrane, integral to membrane molecular_function, transferase activity Human SAMD9 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0043231=GO_REF:0000052} Q5K651 Sterile alpha motif domain-containing protein 9 protein 20111111 {GO:0005737=IDA, GO:0043231=IDA} cytoplasm, intracellular membrane-bounded organelle Human SAMHD1 IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0005622=PMID:11064105, GO:0006955=PMID:11064105, GO:0051607=PMID:19525956, GO:0008081=GO_REF:0000002, GO:0003723=PMID:22461318, GO:0045087=GO_REF:0000037, GO:0045088=PMID:19525956, GO:0005634=GO_REF:0000054, GO:0003676=PMID:22461318, GO:0046872=GO_REF:0000002} Q9Y3Z3 SAM domain and HD domain-containing protein 1 protein 20130415 {GO:0005515=IPI, GO:0005622=NAS, GO:0006955=NAS, GO:0051607=IMP, GO:0008081=IEA, GO:0003723=IDA, GO:0045087=IEA, GO:0045088=IMP, GO:0005634=IDA, GO:0003676=IDA, GO:0046872=IEA} defense response to virus, immune response, innate immune response, regulation of innate immune response intracellular, nucleus RNA binding, metal ion binding, nucleic acid binding, phosphoric diester hydrolase activity, protein binding Human UniProtKB:P58753 SAMM50 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005515=PMID:21081504, GO:0001401=PMID:15644312, GO:0019867=GO_REF:0000002, GO:0006626=Reactome:REACT_118595, GO:0005743=GO_REF:0000019, GO:0005741=PMID:15644312, GO:0016021=PMID:15644312, GO:0045040=PMID:15644312, GO:0044267=Reactome:REACT_17015} Q9Y512 Sorting and assembly machinery component 50 homolog protein 20101115 {GO:0005739=IDA, GO:0005515=IPI, GO:0001401=IMP, GO:0019867=IEA, GO:0006626=TAS, GO:0005743=IEA, GO:0005741=IDA, GO:0016021=IDA, GO:0045040=IDA, GO:0044267=TAS} cellular protein metabolic process, protein import into mitochondrial outer membrane, protein targeting to mitochondrion integral to membrane, mitochondrial inner membrane, mitochondrial outer membrane, mitochondrial sorting and assembly machinery complex, mitochondrion, outer membrane protein binding Human SAMSN1 MGI UniProtKB {GO:0050869=GO_REF:0000024, GO:0050732=GO_REF:0000024, GO:0001784=PMID:15381729, GO:0005634=PMID:11594764, GO:0002820=GO_REF:0000024, GO:0001726=GO_REF:0000039, GO:0005829=GO_REF:0000019} Q9NSI8 SAM domain-containing protein SAMSN-1 protein 20060224 {GO:0050869=ISS, GO:0050732=ISS, GO:0001784=IDA, GO:0005634=IDA, GO:0002820=ISS, GO:0001726=IEA, GO:0005829=IEA} negative regulation of B cell activation, negative regulation of adaptive immune response, negative regulation of peptidyl-tyrosine phosphorylation cytosol, nucleus, ruffle phosphotyrosine binding Human SAP130 BHF-UCL UniProtKB {GO:0043966=PMID:11564863, GO:0030914=PMID:11564863, GO:0003713=PMID:11564863, GO:0000122=PMID:22783022, GO:0004402=PMID:11564863, GO:0006351=GO_REF:0000037} Q9H0E3 Histone deacetylase complex subunit SAP130 protein 20121121 {GO:0043966=IDA, GO:0030914=IDA, GO:0003713=IDA, GO:0000122=IMP, GO:0004402=IDA, GO:0006351=IEA} histone H3 acetylation, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent STAGA complex histone acetyltransferase activity, transcription coactivator activity Human SAP18 HPA UniProtKB {GO:0005515=PMID:9150135, GO:0005737=GO_REF:0000039, GO:0000118=PMID:9150135, GO:0005886=GO_REF:0000052, GO:0006357=PMID:9150135, GO:0003714=PMID:9150135, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037} O00422 Histone deacetylase complex subunit SAP18 protein 20101115 {GO:0005515=IPI, GO:0005737=IEA, GO:0000118=TAS, GO:0005886=IDA, GO:0006357=TAS, GO:0003714=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0006351=IEA} regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, histone deacetylase complex, nucleolus, nucleus, plasma membrane protein binding, transcription corepressor activity Human SAP25 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q8TEE9 Histone deacetylase complex subunit SAP25 protein 20130413 {GO:0005737=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 SAP30 UniProtKB UniProtKB {GO:0005515=PMID:9651585, GO:0006355=PMID:9651585, GO:0000118=PMID:9651585, GO:0003714=PMID:9651585, GO:0000122=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037} O75446 Histone deacetylase complex subunit SAP30 protein 20071114 {GO:0005515=IPI, GO:0006355=IDA, GO:0000118=IDA, GO:0003714=IDA, GO:0000122=IEA, GO:0003677=IEA, GO:0046872=IEA, GO:0006351=IEA} negative regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription, DNA-dependent histone deacetylase complex DNA binding, metal ion binding, protein binding, transcription corepressor activity Human SAP30BP HPA UniProtKB {GO:0005515=PMID:18255255, GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0045111=GO_REF:0000052, GO:0006917=PMID:9651585, GO:0006351=GO_REF:0000037} Q9UHR5 SAP30-binding protein protein 20110516 {GO:0005515=IPI, GO:0006355=IEA, GO:0005730=IDA, GO:0006915=IEA, GO:0005634=IDA, GO:0045111=IDA, GO:0006917=IDA, GO:0006351=IEA} apoptotic process, induction of apoptosis, regulation of transcription, DNA-dependent, transcription, DNA-dependent intermediate filament cytoskeleton, nucleolus, nucleus protein binding Human SAP30L UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9HAJ7 Histone deacetylase complex subunit SAP30L protein 20130413 {GO:0006355=IEA, GO:0005730=IEA, GO:0003677=IEA, GO:0046872=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus DNA binding, metal ion binding Human UniProtKB-SubCell:SL-0188 SAR1A GOC UniProtKB {GO:0006184=GO_REF:0000029, GO:0006888=GO_REF:0000029, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000029, GO:0016529=GO_REF:0000019, GO:0005794=GO_REF:0000039, GO:0005783=GO_REF:0000052, GO:0003924=GO_REF:0000029, GO:0016192=GO_REF:0000019, GO:0005525=GO_REF:0000037, GO:0006886=GO_REF:0000002} Q9NR31 GTP-binding protein SAR1a protein 20130413 {GO:0006184=NAS, GO:0006888=NAS, GO:0005622=IEA, GO:0005737=NAS, GO:0016529=IEA, GO:0005794=IEA, GO:0005783=IDA, GO:0003924=NAS, GO:0016192=IEA, GO:0005525=IEA, GO:0006886=IEA} ER to Golgi vesicle-mediated transport, GTP catabolic process, intracellular protein transport, vesicle-mediated transport Golgi apparatus, cytoplasm, endoplasmic reticulum, intracellular, sarcoplasmic reticulum GTP binding, GTPase activity Human SAR1B HPA UniProtKB {GO:0012507=Reactome:REACT_75799, GO:0002474=Reactome:REACT_75820, GO:0005794=GO_REF:0000038, GO:0005783=GO_REF:0000052, GO:0003924=Reactome:REACT_75799, GO:0048208=Reactome:REACT_12507, GO:0044281=Reactome:REACT_111217, GO:0005525=GO_REF:0000037, GO:0006886=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_75799, GO:0006184=Reactome:REACT_75799, GO:0005622=GO_REF:0000002, GO:0006888=Reactome:REACT_11203, GO:0019886=Reactome:REACT_121399, GO:0032580=GO_REF:0000039, GO:0005789=Reactome:REACT_121121, GO:0016192=GO_REF:0000038, GO:0044267=Reactome:REACT_17015, GO:0016044=Reactome:REACT_11123, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q9Y6B6 GTP-binding protein SAR1b protein 20080205 {GO:0012507=TAS, GO:0002474=TAS, GO:0005794=IEA, GO:0005783=IDA, GO:0003924=TAS, GO:0048208=TAS, GO:0044281=TAS, GO:0005525=IEA, GO:0006886=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0006184=TAS, GO:0005622=IEA, GO:0006888=TAS, GO:0019886=TAS, GO:0032580=IEA, GO:0005789=TAS, GO:0016192=IEA, GO:0044267=TAS, GO:0016044=TAS, GO:0043687=TAS, GO:0018279=TAS} COPII vesicle coating, ER to Golgi vesicle-mediated transport, GTP catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class II, antigen processing and presentation of peptide antigen via MHC class I, cellular membrane organization, cellular protein metabolic process, intracellular protein transport, post-translational protein modification, protein N-linked glycosylation via asparagine, small molecule metabolic process, vesicle-mediated transport ER to Golgi transport vesicle membrane, Golgi apparatus, Golgi cisterna membrane, cytosol, endoplasmic reticulum, endoplasmic reticulum membrane, intracellular GTP binding, GTPase activity, metal ion binding Human SARDH UniProtKB UniProtKB {GO:0005739=GO_REF:0000024, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000002, GO:0005759=GO_REF:0000039, GO:0016491=GO_REF:0000002, GO:0006546=GO_REF:0000002, GO:0004047=GO_REF:0000002, GO:0008480=GO_REF:0000003} Q9UL12 Sarcosine dehydrogenase, mitochondrial protein 20041006 {GO:0005739=ISS, GO:0008150=ND, GO:0005737=IEA, GO:0005759=IEA, GO:0016491=IEA, GO:0006546=IEA, GO:0004047=IEA, GO:0008480=IEA} biological_process, glycine catabolic process cytoplasm, mitochondrial matrix, mitochondrion aminomethyltransferase activity, oxidoreductase activity, sarcosine dehydrogenase activity Human UniProtKB:Q99LB7 SARM1 Reactome UniProtKB {GO:0030424=GO_REF:0000039, GO:0034142=Reactome:REACT_6894, GO:0030054=GO_REF:0000037, GO:0005874=GO_REF:0000024, GO:1901214=GO_REF:0000024, GO:0045202=GO_REF:0000024, GO:0002224=Reactome:REACT_6966, GO:0030425=GO_REF:0000024, GO:0005829=Reactome:REACT_150310, GO:0005739=PMID:22145856, GO:0048814=GO_REF:0000024, GO:0007165=GO_REF:0000002, GO:0002756=Reactome:REACT_6809, GO:0005737=GO_REF:0000024, GO:0045087=Reactome:REACT_6802, GO:0034138=Reactome:REACT_6783} Q6SZW1 Sterile alpha and TIR motif-containing protein 1 protein 20121102 {GO:0030424=IEA, GO:0034142=TAS, GO:0030054=IEA, GO:0005874=ISS, GO:1901214=ISS, GO:0045202=ISS, GO:0002224=TAS, GO:0030425=ISS, GO:0005829=TAS, GO:0005739=IDA, GO:0048814=ISS, GO:0007165=IEA, GO:0002756=TAS, GO:0005737=ISS, GO:0045087=TAS, GO:0034138=TAS} MyD88-independent toll-like receptor signaling pathway, innate immune response, regulation of dendrite morphogenesis, regulation of neuron death, signal transduction, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor signaling pathway axon, cell junction, cytoplasm, cytosol, dendrite, microtubule, mitochondrion, synapse Human SARNP HPA UniProtKB {GO:0006355=GO_REF:0000029, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000029, GO:0003677=GO_REF:0000037, GO:0006417=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0043231=GO_REF:0000052} P82979 SAP domain-containing ribonucleoprotein protein 20120912 {GO:0006355=NAS, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=NAS, GO:0003677=IEA, GO:0006417=IEA, GO:0006351=IEA, GO:0043231=IDA} regulation of transcription, DNA-dependent, regulation of translation, transcription, DNA-dependent intracellular membrane-bounded organelle, nucleolus, nucleus DNA binding, RNA binding, nucleic acid binding Human SARS HPA UniProtKB {GO:0005739=GO_REF:0000019, GO:0010467=Reactome:REACT_71, GO:0005737=GO_REF:0000052, GO:0006434=GO_REF:0000002, GO:0003723=PMID:9431993, GO:0004828=GO_REF:0000002, GO:0006412=PMID:9431993, GO:0097056=GO_REF:0000041, GO:0005524=GO_REF:0000002, GO:0008033=PMID:9431993, GO:0006418=Reactome:REACT_15482, GO:0005829=Reactome:REACT_15400} Q5T5C7 Serine--tRNA ligase, cytoplasmic protein 20090616 {GO:0005739=IEA, GO:0010467=TAS, GO:0005737=IDA, GO:0006434=IEA, GO:0003723=TAS, GO:0004828=IEA, GO:0006412=TAS, GO:0097056=IEA, GO:0005524=IEA, GO:0008033=TAS, GO:0006418=TAS, GO:0005829=TAS} gene expression, selenocysteinyl-tRNA(Sec) biosynthetic process, seryl-tRNA aminoacylation, tRNA aminoacylation for protein translation, tRNA processing, translation cytoplasm, cytosol, mitochondrion ATP binding, RNA binding, serine-tRNA ligase activity Human SARS2 Reactome UniProtKB {GO:0005739=PMID:10764807, GO:0010467=Reactome:REACT_71, GO:0030163=GO_REF:0000002, GO:0006434=PMID:10764807, GO:0005737=GO_REF:0000002, GO:0005759=Reactome:REACT_15501, GO:0004828=Reactome:REACT_15501, GO:0097056=GO_REF:0000041, GO:0005524=PMID:10764807, GO:0006418=Reactome:REACT_15482} Q9NP81 Serine--tRNA ligase, mitochondrial protein 20130213 {GO:0005739=ISS, GO:0010467=TAS, GO:0030163=IEA, GO:0006434=ISS, GO:0005737=IEA, GO:0005759=TAS, GO:0004828=TAS, GO:0097056=IEA, GO:0005524=ISS, GO:0006418=TAS} gene expression, protein catabolic process, selenocysteinyl-tRNA(Sec) biosynthetic process, seryl-tRNA aminoacylation, tRNA aminoacylation for protein translation cytoplasm, mitochondrial matrix, mitochondrion ATP binding, serine-tRNA ligase activity Human SART1 HPA UniProtKB {GO:0005515=PMID:17000644, GO:0005794=GO_REF:0000052, GO:0015030=PMID:16687569, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0071013=PMID:11991638, GO:0000387=PMID:16687569, GO:0097193=PMID:16158934, GO:0005829=PMID:10929426, GO:0003674=GO_REF:0000015, GO:0005737=PMID:9856836, GO:0000398=PMID:11991638, GO:0007050=PMID:16158934, GO:0005654=PMID:16687569, GO:0045585=PMID:10209962} O43290 U4/U6.U5 tri-snRNP-associated protein 1 protein 20110516 {GO:0005515=IPI, GO:0005794=IDA, GO:0015030=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0071013=IDA, GO:0000387=TAS, GO:0097193=NAS, GO:0005829=TAS, GO:0003674=ND, GO:0005737=TAS, GO:0000398=IC, GO:0007050=NAS, GO:0005654=IDA, GO:0045585=IDA} cell cycle arrest, intrinsic apoptotic signaling pathway, mRNA splicing, via spliceosome, positive regulation of cytotoxic T cell differentiation, spliceosomal snRNP assembly Cajal body, Golgi apparatus, catalytic step 2 spliceosome, cytoplasm, cytosol, nucleolus, nucleoplasm, nucleus molecular_function, protein binding Human SART3 HPA UniProtKB {GO:0005515=PMID:11477570, GO:0005622=GO_REF:0000002, GO:0006396=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0016607=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0043231=GO_REF:0000052} Q15020 Squamous cell carcinoma antigen recognized by T-cells 3 protein 20120912 {GO:0005515=IPI, GO:0005622=IEA, GO:0006396=IEA, GO:0005737=IDA, GO:0016607=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0003676=IEA, GO:0043231=IDA} RNA processing cytoplasm, intracellular, intracellular membrane-bounded organelle, nuclear speck RNA binding, nucleic acid binding, nucleotide binding, protein binding Human SASH1 null null {} null null null null {} null null null SASH3 ENSEMBL UniProtKB {GO:0032729=GO_REF:0000019, GO:0032753=GO_REF:0000019, GO:0046622=GO_REF:0000019, GO:0032733=GO_REF:0000019, GO:0032760=GO_REF:0000019, GO:0030890=GO_REF:0000019, GO:0032743=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0002726=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0048873=GO_REF:0000019, GO:0002639=GO_REF:0000019, GO:0043372=GO_REF:0000019, GO:0042102=GO_REF:0000019} O75995 SAM and SH3 domain-containing protein 3 protein 20130413 {GO:0032729=IEA, GO:0032753=IEA, GO:0046622=IEA, GO:0032733=IEA, GO:0032760=IEA, GO:0030890=IEA, GO:0032743=IEA, GO:0005634=IEA, GO:0002726=IEA, GO:0005737=IEA, GO:0048873=IEA, GO:0002639=IEA, GO:0043372=IEA, GO:0042102=IEA} homeostasis of number of cells within a tissue, positive regulation of B cell proliferation, positive regulation of CD4-positive, alpha-beta T cell differentiation, positive regulation of T cell cytokine production, positive regulation of T cell proliferation, positive regulation of immunoglobulin production, positive regulation of interferon-gamma production, positive regulation of interleukin-10 production, positive regulation of interleukin-2 production, positive regulation of interleukin-4 production, positive regulation of organ growth, positive regulation of tumor necrosis factor production cytoplasm, nucleus Human Ensembl:ENSMUSP00000033427 SASS6 UniProtKB UniProtKB {GO:0005515=PMID:21725316, GO:0051298=PMID:15665853, GO:0005813=PMID:21399614, GO:0007099=PMID:17681131, GO:0005814=PMID:17681131} Q6UVJ0 Spindle assembly abnormal protein 6 homolog protein 20110517 {GO:0005515=IPI, GO:0051298=IMP, GO:0005813=IDA, GO:0007099=IMP, GO:0005814=IDA} centriole replication, centrosome duplication centriole, centrosome protein binding Human SAT1 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0008080=GO_REF:0000002, GO:0001525=PMID:11866539, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_14817, GO:0005622=GO_REF:0000054, GO:0034641=Reactome:REACT_13, GO:0006596=Reactome:REACT_14805, GO:0019809=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0006595=Reactome:REACT_14820, GO:0004145=GO_REF:0000003, GO:0009447=GO_REF:0000041} P21673 Diamine acetyltransferase 1 protein 20130415 {GO:0005515=IPI, GO:0008080=IEA, GO:0001525=IEP, GO:0044281=TAS, GO:0005829=TAS, GO:0005622=IDA, GO:0034641=TAS, GO:0006596=TAS, GO:0019809=IEA, GO:0042127=IEA, GO:0006595=TAS, GO:0004145=IEA, GO:0009447=IEA} angiogenesis, cellular nitrogen compound metabolic process, polyamine biosynthetic process, polyamine metabolic process, putrescine catabolic process, regulation of cell proliferation, small molecule metabolic process cytosol, intracellular N-acetyltransferase activity, diamine N-acetyltransferase activity, protein binding, spermidine binding Human UniProtKB:Q9BQ70 SAT2 UniPathway UniProtKB {GO:0005737=GO_REF:0000039, GO:0008080=GO_REF:0000002, GO:0009447=GO_REF:0000041, GO:0004145=GO_REF:0000003} Q96F10 Diamine acetyltransferase 2 protein 20130413 {GO:0005737=IEA, GO:0008080=IEA, GO:0009447=IEA, GO:0004145=IEA} putrescine catabolic process cytoplasm N-acetyltransferase activity, diamine N-acetyltransferase activity Human UniPathway:UPA00188 SATB1 IntAct UniProtKB {GO:0005515=PMID:18408014, GO:0003700=GO_REF:0000019, GO:0016571=GO_REF:0000019, GO:0006325=PMID:1505028, GO:0006915=Reactome:REACT_578, GO:0043367=GO_REF:0000019, GO:0005634=PMID:18408014, GO:0000122=PMID:15851481, GO:0003677=GO_REF:0000019, GO:0006921=Reactome:REACT_995, GO:0006351=GO_REF:0000037, GO:0016363=GO_REF:0000039, GO:0043565=GO_REF:0000002, GO:0005720=GO_REF:0000019, GO:0003690=PMID:1505028, GO:0008544=GO_REF:0000019, GO:0043374=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0016605=PMID:18408014, GO:0060004=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0005654=Reactome:REACT_22225, GO:0006338=GO_REF:0000019, GO:0050798=GO_REF:0000019} Q01826 DNA-binding protein SATB1 protein 20130415 {GO:0005515=IPI, GO:0003700=IEA, GO:0016571=IEA, GO:0006325=TAS, GO:0006915=TAS, GO:0043367=IEA, GO:0005634=IDA, GO:0000122=IMP, GO:0003677=IEA, GO:0006921=TAS, GO:0006351=IEA, GO:0016363=IEA, GO:0043565=IEA, GO:0005720=IEA, GO:0003690=TAS, GO:0008544=IEA, GO:0043374=IEA, GO:0019048=IEA, GO:0016605=IDA, GO:0060004=IEA, GO:0003682=IEA, GO:0005654=TAS, GO:0006338=IEA, GO:0050798=IEA} CD4-positive, alpha-beta T cell differentiation, CD8-positive, alpha-beta T cell differentiation, activated T cell proliferation, apoptotic process, cellular component disassembly involved in execution phase of apoptosis, chromatin organization, chromatin remodeling, epidermis development, histone methylation, negative regulation of transcription from RNA polymerase II promoter, reflex, transcription, DNA-dependent, virus-host interaction PML body, nuclear heterochromatin, nuclear matrix, nucleoplasm, nucleus DNA binding, chromatin binding, double-stranded DNA binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:P63165 SATB2 HPA UniProtKB {GO:0005667=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0051216=GO_REF:0000019, GO:0071310=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0048704=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0000122=GO_REF:0000019, GO:0016363=GO_REF:0000039, GO:0006351=GO_REF:0000037, GO:0009880=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0000118=GO_REF:0000019, GO:0002076=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:0006338=GO_REF:0000019, GO:0001764=GO_REF:0000019} Q9UPW6 DNA-binding protein SATB2 protein 20080205 {GO:0005667=IEA, GO:0003700=IEA, GO:0051216=IEA, GO:0071310=IEA, GO:0005730=IDA, GO:0048704=IEA, GO:0005634=IDA, GO:0000122=IEA, GO:0016363=IEA, GO:0006351=IEA, GO:0009880=IEA, GO:0043565=IEA, GO:0005737=IDA, GO:0000118=IEA, GO:0002076=IEA, GO:0045944=IEA, GO:0003682=IEA, GO:0060021=IEA, GO:0006338=IEA, GO:0001764=IEA} cartilage development, cellular response to organic substance, chromatin remodeling, embryonic pattern specification, embryonic skeletal system morphogenesis, negative regulation of transcription from RNA polymerase II promoter, neuron migration, osteoblast development, palate development, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, histone deacetylase complex, nuclear matrix, nucleolus, nucleus, transcription factor complex chromatin binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human SAV1 IntAct UniProtKB {GO:0005515=PMID:23455922, GO:0060044=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0060412=GO_REF:0000019, GO:0050680=GO_REF:0000019, GO:0005634=PMID:19212654, GO:0035329=Reactome:REACT_118607, GO:2000036=GO_REF:0000019, GO:0005829=Reactome:REACT_118858, GO:0060575=GO_REF:0000019, GO:0007165=GO_REF:0000002, GO:0005737=PMID:19212654, GO:0030216=GO_REF:0000019, GO:0060487=GO_REF:0000019, GO:0001942=GO_REF:0000019} Q9H4B6 Protein salvador homolog 1 protein 20130415 {GO:0005515=IPI, GO:0060044=IEA, GO:0043065=IEA, GO:0060412=IEA, GO:0050680=IEA, GO:0005634=IDA, GO:0035329=TAS, GO:2000036=IEA, GO:0005829=TAS, GO:0060575=IEA, GO:0007165=IEA, GO:0005737=IDA, GO:0030216=IEA, GO:0060487=IEA, GO:0001942=IEA} hair follicle development, hippo signaling cascade, intestinal epithelial cell differentiation, keratinocyte differentiation, lung epithelial cell differentiation, negative regulation of cardiac muscle cell proliferation, negative regulation of epithelial cell proliferation, positive regulation of apoptotic process, regulation of stem cell maintenance, signal transduction, ventricular septum morphogenesis cytoplasm, cytosol, nucleus protein binding Human UniProtKB:Q13188 SBDS UniProtKB UniProtKB {GO:0008017=PMID:18324336, GO:0005515=PMID:17643419, GO:0042256=PMID:21536732, GO:0008283=PMID:19759903, GO:0030595=PMID:14743349, GO:0006364=PMID:17643419, GO:0043148=PMID:18324336, GO:0001833=GO_REF:0000019, GO:0005730=PMID:17475909, GO:0005634=PMID:18324336, GO:0030282=PMID:17920346, GO:0048539=PMID:15342903, GO:0019843=PMID:17475909, GO:0005737=PMID:18324336, GO:0000922=PMID:19759903, GO:0043022=PMID:21536732, GO:0005654=GO_REF:0000039, GO:0042273=GO_REF:0000033} Q9Y3A5 Ribosome maturation protein SBDS protein 20110516 {GO:0008017=IDA, GO:0005515=IPI, GO:0042256=IDA, GO:0008283=IMP, GO:0030595=IDA, GO:0006364=IMP, GO:0043148=IDA, GO:0001833=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0030282=IMP, GO:0048539=IMP, GO:0019843=IDA, GO:0005737=IDA, GO:0000922=IDA, GO:0043022=IDA, GO:0005654=IEA, GO:0042273=IBA} bone marrow development, bone mineralization, cell proliferation, inner cell mass cell proliferation, leukocyte chemotaxis, mature ribosome assembly, mitotic spindle stabilization, rRNA processing, ribosomal large subunit biogenesis cytoplasm, nucleolus, nucleoplasm, nucleus, spindle pole microtubule binding, protein binding, rRNA binding, ribosome binding Human SBF1 UniProtKB UniProtKB {GO:0017112=PMID:20937701, GO:0016791=GO_REF:0000002, GO:0006470=PMID:9736772, GO:0005543=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0016021=PMID:9736772, GO:0008138=PMID:9736772, GO:0007283=GO_REF:0000019} O95248 Myotubularin-related protein 5 protein 20121004 {GO:0017112=IDA, GO:0016791=IEA, GO:0006470=TAS, GO:0005543=IEA, GO:0005634=IEA, GO:0016021=TAS, GO:0008138=TAS, GO:0007283=IEA} protein dephosphorylation, spermatogenesis integral to membrane, nucleus Rab guanyl-nucleotide exchange factor activity, phosphatase activity, phospholipid binding, protein tyrosine/serine/threonine phosphatase activity Human SBF2 UniProtKB UniProtKB {GO:0005515=PMID:15998640, GO:0017112=PMID:20937701, GO:0005774=GO_REF:0000019, GO:0016791=GO_REF:0000002, GO:0051262=GO_REF:0000019, GO:0019208=GO_REF:0000019, GO:0016020=PMID:15998640, GO:0019902=GO_REF:0000019, GO:0042552=PMID:15998640, GO:0035091=GO_REF:0000019, GO:0042803=GO_REF:0000019} Q86WG5 Myotubularin-related protein 13 protein 20121004 {GO:0005515=IPI, GO:0017112=IDA, GO:0005774=IEA, GO:0016791=IEA, GO:0051262=IEA, GO:0019208=IEA, GO:0016020=IDA, GO:0019902=IEA, GO:0042552=NAS, GO:0035091=IEA, GO:0042803=IEA} myelination, protein tetramerization membrane, vacuolar membrane Rab guanyl-nucleotide exchange factor activity, phosphatase activity, phosphatase binding, phosphatase regulator activity, phosphatidylinositol binding, protein binding, protein homodimerization activity Human SBK1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0004674=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q52WX2 Serine/threonine-protein kinase SBK1 protein 20130413 {GO:0005737=IEA, GO:0004674=IEA, GO:0005524=IEA} cytoplasm ATP binding, protein serine/threonine kinase activity Human UniProtKB-SubCell:SL-0086 SBNO1 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0006355=GO_REF:0000002, GO:0005575=GO_REF:0000015} A3KN83 Protein strawberry notch homolog 1 protein 20080229 {GO:0008150=ND, GO:0003674=ND, GO:0006355=IEA, GO:0005575=ND} biological_process, regulation of transcription, DNA-dependent cellular_component molecular_function Human SBSN UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q6UWP8 Suprabasin protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 SCAF1 UniProtKB UniProtKB {GO:0006397=GO_REF:0000019, GO:0008380=GO_REF:0000037, GO:0006366=GO_REF:0000019, GO:0003723=GO_REF:0000037, GO:0019904=GO_REF:0000019, GO:0005634=GO_REF:0000039} Q9H7N4 Splicing factor, arginine/serine-rich 19 protein 20130413 {GO:0006397=IEA, GO:0008380=IEA, GO:0006366=IEA, GO:0003723=IEA, GO:0019904=IEA, GO:0005634=IEA} RNA splicing, mRNA processing, transcription from RNA polymerase II promoter nucleus RNA binding, protein domain specific binding Human UniProtKB-SubCell:SL-0191 SCAF11 HPA UniProtKB {GO:0006397=PMID:9447963, GO:0005515=PMID:9447963, GO:0008380=PMID:9447963, GO:0000245=PMID:9447963, GO:0000375=PMID:9447963, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002} Q99590 Protein SCAF11 protein 20111111 {GO:0006397=TAS, GO:0005515=IPI, GO:0008380=IDA, GO:0000245=IDA, GO:0000375=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA} RNA splicing, RNA splicing, via transesterification reactions, mRNA processing, spliceosomal complex assembly nucleolus, nucleus protein binding, zinc ion binding NOT Human SCAF4 HPA UniProtKB {GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002} O95104 Splicing factor, arginine/serine-rich 15 protein 20090616 {GO:0000166=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA} nucleolus, nucleus RNA binding, nucleic acid binding, nucleotide binding NOT Human SCAF8 HPA UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0043175=PMID:18550522, GO:0005681=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0016363=GO_REF:0000024} Q9UPN6 Protein SCAF8 protein 20111111 {GO:0008380=IEA, GO:0006397=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0043175=IPI, GO:0005681=IEA, GO:0005634=IDA, GO:0003676=IEA, GO:0016363=ISS} RNA splicing, mRNA processing nuclear matrix, nucleolus, nucleus, spliceosomal complex RNA binding, RNA polymerase core enzyme binding, nucleic acid binding, nucleotide binding NOT Human SCAI UniProtKB UniProtKB {GO:0005515=PMID:19350017, GO:0030336=PMID:19350017, GO:0005737=GO_REF:0000039, GO:0006355=GO_REF:0000037, GO:0003714=PMID:19350017, GO:0035024=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8N9R8 Protein SCAI protein 20090619 {GO:0005515=IPI, GO:0030336=IMP, GO:0005737=IEA, GO:0006355=IEA, GO:0003714=IMP, GO:0035024=ISS, GO:0005634=IEA, GO:0016021=IEA, GO:0006351=IEA} negative regulation of Rho protein signal transduction, negative regulation of cell migration, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, integral to membrane, nucleus protein binding, transcription corepressor activity Human UniProtKB:P11831 SCAMP1 PINC UniProtKB {GO:0005515=PMID:15840657, GO:0005802=PMID:15840657, GO:0005794=GO_REF:0000039, GO:0006892=PMID:9378760, GO:0016021=PMID:15840657, GO:0015031=PMID:15840657, GO:0055038=PMID:15840657} O15126 Secretory carrier-associated membrane protein 1 protein 20030904 {GO:0005515=IPI, GO:0005802=IDA, GO:0005794=IEA, GO:0006892=TAS, GO:0016021=IDA, GO:0015031=IDA, GO:0055038=IDA} post-Golgi vesicle-mediated transport, protein transport Golgi apparatus, integral to membrane, recycling endosome membrane, trans-Golgi network protein binding Human SCAMP2 HPA UniProtKB {GO:0005515=PMID:16870614, GO:0005794=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0006892=PMID:9378760, GO:0005634=GO_REF:0000052, GO:0016021=PMID:15840657, GO:0015031=PMID:15840657, GO:0055038=PMID:15840657, GO:0032588=PMID:15840657, GO:0043231=GO_REF:0000052} O15127 Secretory carrier-associated membrane protein 2 protein 20090616 {GO:0005515=IPI, GO:0005794=IDA, GO:0005730=IDA, GO:0006892=TAS, GO:0005634=IDA, GO:0016021=IDA, GO:0015031=IDA, GO:0055038=IDA, GO:0032588=IDA, GO:0043231=IDA} post-Golgi vesicle-mediated transport, protein transport Golgi apparatus, integral to membrane, intracellular membrane-bounded organelle, nucleolus, nucleus, recycling endosome membrane, trans-Golgi network membrane protein binding Human SCAMP3 PINC UniProtKB {GO:0000139=GO_REF:0000019, GO:0006892=PMID:9378760, GO:0032526=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0015031=GO_REF:0000037} O14828 Secretory carrier-associated membrane protein 3 protein 20030904 {GO:0000139=IEA, GO:0006892=TAS, GO:0032526=IEA, GO:0016021=IEA, GO:0015031=IEA} post-Golgi vesicle-mediated transport, protein transport, response to retinoic acid Golgi membrane, integral to membrane Human SCAMP4 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0015031=GO_REF:0000037} Q969E2 Secretory carrier-associated membrane protein 4 protein 20130413 {GO:0016021=IEA, GO:0015031=IEA} protein transport integral to membrane Human UniProtKB-KW:KW-0812 SCAMP5 IntAct UniProtKB {GO:0005515=PMID:19234194, GO:0034976=PMID:19240033, GO:0030054=GO_REF:0000037, GO:0005886=PMID:19234194, GO:0031201=PMID:19234194, GO:0050715=PMID:19234194, GO:0015031=GO_REF:0000037, GO:0006887=GO_REF:0000037, GO:0032588=PMID:15840657, GO:0000139=PMID:19234194, GO:0045956=PMID:19234194, GO:0045806=PMID:19240033, GO:0030672=GO_REF:0000039, GO:0016021=PMID:19234194, GO:0055038=PMID:15840657} Q8TAC9 Secretory carrier-associated membrane protein 5 protein 20130415 {GO:0005515=IPI, GO:0034976=IDA, GO:0030054=IEA, GO:0005886=IDA, GO:0031201=IDA, GO:0050715=IDA, GO:0015031=IEA, GO:0006887=IEA, GO:0032588=IDA, GO:0000139=IDA, GO:0045956=IDA, GO:0045806=IDA, GO:0030672=IEA, GO:0016021=IDA, GO:0055038=IDA} exocytosis, negative regulation of endocytosis, positive regulation of calcium ion-dependent exocytosis, positive regulation of cytokine secretion, protein transport, response to endoplasmic reticulum stress Golgi membrane, SNARE complex, cell junction, integral to membrane, plasma membrane, recycling endosome membrane, synaptic vesicle membrane, trans-Golgi network membrane protein binding Human UniProtKB:P46097 SCAND1 GOC UniProtKB {GO:0003700=GO_REF:0000024, GO:0006366=GO_REF:0000033, GO:0006357=GO_REF:0000033, GO:0000981=GO_REF:0000033, GO:0003713=GO_REF:0000033, GO:0016032=GO_REF:0000002, GO:0005634=GO_REF:0000054, GO:0042802=GO_REF:0000024} P57086 SCAN domain-containing protein 1 protein 20130413 {GO:0003700=ISS, GO:0006366=IBA, GO:0006357=IBA, GO:0000981=IBA, GO:0003713=IBA, GO:0016032=IEA, GO:0005634=IDA, GO:0042802=ISS} regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter, viral reproduction nucleus identical protein binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity, transcription coactivator activity Human PANTHER:PTN000003381 SCAP Reactome UniProtKB {GO:0005515=PMID:19706601, GO:0001666=GO_REF:0000019, GO:0032868=GO_REF:0000019, GO:0012507=GO_REF:0000039, GO:0005794=PMID:11726962, GO:0005783=PMID:11726962, GO:0045541=PMID:11969205, GO:0007568=GO_REF:0000019, GO:0045540=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0045716=PMID:11726974, GO:0032403=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0032933=PMID:11726962, GO:0000139=Reactome:REACT_147792, GO:0042304=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0051082=PMID:11726962, GO:0016021=PMID:11726962, GO:0008203=GO_REF:0000019} Q12770 Sterol regulatory element-binding protein cleavage-activating protein protein 20111013 {GO:0005515=IPI, GO:0001666=IEA, GO:0032868=IEA, GO:0012507=IEA, GO:0005794=NAS, GO:0005783=NAS, GO:0045541=NAS, GO:0007568=IEA, GO:0045540=IEA, GO:0044281=TAS, GO:0045716=NAS, GO:0032403=IEA, GO:0043234=IEA, GO:0032933=IMP, GO:0000139=TAS, GO:0042304=IEA, GO:0005789=IEA, GO:0051082=NAS, GO:0016021=NAS, GO:0008203=IEA} SREBP signaling pathway, aging, cholesterol metabolic process, negative regulation of cholesterol biosynthetic process, positive regulation of low-density lipoprotein particle receptor biosynthetic process, regulation of cholesterol biosynthetic process, regulation of fatty acid biosynthetic process, response to hypoxia, response to insulin stimulus, small molecule metabolic process ER to Golgi transport vesicle membrane, Golgi apparatus, Golgi membrane, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, protein complex protein binding, protein complex binding, unfolded protein binding Human SCAPER UniProtKB UniProtKB {GO:0005783=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0046872=GO_REF:0000037} Q9BY12 S phase cyclin A-associated protein in the endoplasmic reticulum protein 20130413 {GO:0005783=IEA, GO:0005634=IEA, GO:0046872=IEA} endoplasmic reticulum, nucleus metal ion binding Human UniProtKB-SubCell:SL-0095 SCARA3 PINC UniProtKB {GO:0009650=PMID:9580669, GO:0005581=GO_REF:0000037, GO:0000139=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0006979=PMID:9580669, GO:0005044=PMID:9580669} Q6AZY7 Scavenger receptor class A member 3 protein 20061107 {GO:0009650=TAS, GO:0005581=IEA, GO:0000139=IEA, GO:0005789=IEA, GO:0016021=IEA, GO:0006979=TAS, GO:0005044=TAS} UV protection, response to oxidative stress Golgi membrane, collagen, endoplasmic reticulum membrane, integral to membrane scavenger receptor activity Human SCARA5 UniProtKB UniProtKB {GO:0006879=GO_REF:0000024, GO:0034605=GO_REF:0000019, GO:0070207=GO_REF:0000024, GO:0009986=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0005887=GO_REF:0000024, GO:0070287=GO_REF:0000024, GO:0006897=GO_REF:0000024, GO:0034755=GO_REF:0000024, GO:0005044=GO_REF:0000002} Q6ZMJ2 Scavenger receptor class A member 5 protein 20090216 {GO:0006879=ISS, GO:0034605=IEA, GO:0070207=ISS, GO:0009986=IEA, GO:0016020=IEA, GO:0005887=ISS, GO:0070287=ISS, GO:0006897=ISS, GO:0034755=ISS, GO:0005044=IEA} cellular iron ion homeostasis, cellular response to heat, endocytosis, iron ion transmembrane transport, protein homotrimerization cell surface, integral to plasma membrane, membrane ferritin receptor activity, scavenger receptor activity Human UniProtKB:Q8K299 SCARB1 GOC UniProtKB {GO:0008035=GO_REF:0000019, GO:0006629=Reactome:REACT_602, GO:0005215=PMID:9211901, GO:0006707=GO_REF:0000019, GO:0005886=PMID:9211901, GO:0006702=GO_REF:0000019, GO:0010899=GO_REF:0000024, GO:0001875=PMID:12651854, GO:0070328=GO_REF:0000024, GO:0031528=GO_REF:0000019, GO:0051856=PMID:19087225, GO:0044281=Reactome:REACT_111217, GO:0042803=GO_REF:0000019, GO:0050764=PMID:9211901, GO:0005545=PMID:9211901, GO:0005737=GO_REF:0000019, GO:0034384=PMID:9211901, GO:0015914=GO_REF:0000024, GO:0034383=GO_REF:0000024, GO:0032497=PMID:12651854, GO:0007155=GO_REF:0000002, GO:0031663=PMID:12651854, GO:0042632=GO_REF:0000024, GO:0033344=PMID:14718538, GO:0010867=GO_REF:0000024, GO:0009986=GO_REF:0000019, GO:0043691=PMID:9211901, GO:0030169=PMID:9211901, GO:0043654=PMID:9211901, GO:0010886=PMID:9211901, GO:0015920=PMID:12651854, GO:0010595=PMID:17574123, GO:0001530=PMID:12651854, GO:0070506=PMID:9211901, GO:0070508=GO_REF:0000024, GO:0043534=GO_REF:0000019, GO:0005887=GO_REF:0000019, GO:0051000=PMID:11792700, GO:0019048=GO_REF:0000037, GO:0005901=PMID:12651854, GO:0034375=GO_REF:0000024, GO:0042060=PMID:17574123, GO:0001935=GO_REF:0000019, GO:0001786=GO_REF:0000024, GO:0042157=Reactome:REACT_13621, GO:0034185=PMID:10764676, GO:0016021=GO_REF:0000038, GO:0034186=PMID:10764676} Q8WTV0 Scavenger receptor class B member 1 protein 20130413 {GO:0008035=IEA, GO:0006629=TAS, GO:0005215=TAS, GO:0006707=IEA, GO:0005886=IDA, GO:0006702=IEA, GO:0010899=ISS, GO:0001875=IDA, GO:0070328=ISS, GO:0031528=IEA, GO:0051856=IMP, GO:0044281=TAS, GO:0042803=IEA, GO:0050764=IC, GO:0005545=TAS, GO:0005737=IEA, GO:0034384=IDA, GO:0015914=ISS, GO:0034383=ISS, GO:0032497=IDA, GO:0007155=IEA, GO:0031663=IDA, GO:0042632=ISS, GO:0033344=ISS, GO:0010867=ISS, GO:0009986=IEA, GO:0043691=IEP, GO:0030169=IDA, GO:0043654=IDA, GO:0010886=IDA, GO:0015920=IDA, GO:0010595=TAS, GO:0001530=IDA, GO:0070506=IDA, GO:0070508=ISS, GO:0043534=IEA, GO:0005887=IEA, GO:0051000=IDA, GO:0019048=IEA, GO:0005901=TAS, GO:0034375=ISS, GO:0042060=TAS, GO:0001935=IEA, GO:0001786=ISS, GO:0042157=TAS, GO:0034185=IPI, GO:0016021=IEA, GO:0034186=IPI} adhesion to symbiont, androgen biosynthetic process, blood vessel endothelial cell migration, cell adhesion, cholesterol catabolic process, cholesterol efflux, cholesterol homeostasis, cholesterol import, detection of lipopolysaccharide, endothelial cell proliferation, high-density lipoprotein particle clearance, high-density lipoprotein particle remodeling, lipid metabolic process, lipopolysaccharide transport, lipopolysaccharide-mediated signaling pathway, lipoprotein metabolic process, low-density lipoprotein particle clearance, phospholipid transport, positive regulation of cholesterol storage, positive regulation of endothelial cell migration, positive regulation of nitric-oxide synthase activity, positive regulation of triglyceride biosynthetic process, recognition of apoptotic cell, regulation of phagocytosis, regulation of phosphatidylcholine catabolic process, reverse cholesterol transport, small molecule metabolic process, triglyceride homeostasis, virus-host interaction, wound healing caveola, cell surface, cytoplasm, integral to membrane, integral to plasma membrane, microvillus membrane, plasma membrane 1-phosphatidylinositol binding, apolipoprotein A-I binding, apolipoprotein binding, high-density lipoprotein particle binding, high-density lipoprotein particle receptor activity, lipopolysaccharide binding, lipopolysaccharide receptor activity, low-density lipoprotein particle binding, phosphatidylserine binding, protein homodimerization activity, transporter activity Human SCARB2 BHF-UCL UniProtKB {GO:0016020=PMID:1374238, GO:0005887=PMID:1374238, GO:0006622=PMID:18022370, GO:0004872=GO_REF:0000002, GO:0016021=GO_REF:0000038, GO:0005765=PMID:18022370, GO:0019899=PMID:18022370, GO:0007155=GO_REF:0000002, GO:0005764=GO_REF:0000002, GO:0043202=PMID:18022370} Q14108 Lysosome membrane protein 2 protein 20110628 {GO:0016020=TAS, GO:0005887=TAS, GO:0006622=IMP, GO:0004872=IEA, GO:0016021=IEA, GO:0005765=ISS, GO:0019899=IPI, GO:0007155=IEA, GO:0005764=IEA, GO:0043202=ISS} cell adhesion, protein targeting to lysosome integral to membrane, integral to plasma membrane, lysosomal lumen, lysosomal membrane, lysosome, membrane enzyme binding, receptor activity Human UniProtKB:O35114 SCARF1 UniProtKB UniProtKB {GO:0016322=GO_REF:0000024, GO:0006707=PMID:9395444, GO:0048680=GO_REF:0000024, GO:0010976=GO_REF:0000024, GO:0030169=PMID:9395444, GO:0016021=PMID:9395444, GO:0007155=GO_REF:0000037, GO:0006898=PMID:9395444, GO:0016358=GO_REF:0000019, GO:0005044=PMID:9395444, GO:0004888=PMID:9395444} Q14162 Scavenger receptor class F member 1 protein 20110224 {GO:0016322=ISS, GO:0006707=IC, GO:0048680=ISS, GO:0010976=ISS, GO:0030169=IDA, GO:0016021=IDA, GO:0007155=IEA, GO:0006898=TAS, GO:0016358=IEA, GO:0005044=IDA, GO:0004888=TAS} cell adhesion, cholesterol catabolic process, dendrite development, neuron remodeling, positive regulation of axon regeneration, positive regulation of neuron projection development, receptor-mediated endocytosis integral to membrane low-density lipoprotein particle binding, scavenger receptor activity, transmembrane signaling receptor activity Human UniProtKB:Q5ND28 SCARF2 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0016021=GO_REF:0000037, GO:0007157=GO_REF:0000019, GO:0005044=GO_REF:0000019} Q96GP6 Scavenger receptor class F member 2 protein 20130415 {GO:0005515=IPI, GO:0016021=IEA, GO:0007157=IEA, GO:0005044=IEA} heterophilic cell-cell adhesion integral to membrane protein binding, scavenger receptor activity Human UniProtKB:P16333 SCCPDH UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0016491=GO_REF:0000037, GO:0030496=PMID:15166316} Q8NBX0 Saccharopine dehydrogenase-like oxidoreductase protein 20110118 {GO:0005739=IEA, GO:0016491=IEA, GO:0030496=IDA} midbody, mitochondrion oxidoreductase activity Human SCD HPA UniProtKB {GO:0005506=GO_REF:0000002, GO:0005783=GO_REF:0000052, GO:0004768=GO_REF:0000003, GO:0005789=GO_REF:0000039, GO:0006633=GO_REF:0000037, GO:0016021=GO_REF:0000037} O00767 Acyl-CoA desaturase protein 20101115 {GO:0005506=IEA, GO:0005783=IDA, GO:0004768=IEA, GO:0005789=IEA, GO:0006633=IEA, GO:0016021=IEA} fatty acid biosynthetic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane iron ion binding, stearoyl-CoA 9-desaturase activity Human SCD5 InterPro UniProtKB {GO:0005506=GO_REF:0000002, GO:0004768=GO_REF:0000003, GO:0005789=GO_REF:0000039, GO:0006633=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0016717=GO_REF:0000002} Q9BSN4 Stearoyl-CoA desaturase 5, isoform CRA_d protein 20130413 {GO:0005506=IEA, GO:0004768=IEA, GO:0005789=IEA, GO:0006633=IEA, GO:0016021=IEA, GO:0016717=IEA} fatty acid biosynthetic process endoplasmic reticulum membrane, integral to membrane iron ion binding, oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water, stearoyl-CoA 9-desaturase activity Human InterPro:IPR015876 SCEL HPA UniProtKB {GO:0005515=PMID:14632196, GO:0005737=PMID:11112355, GO:0008544=PMID:9813070, GO:0005886=GO_REF:0000052, GO:0030216=PMID:14632196, GO:0008270=GO_REF:0000002, GO:0009790=PMID:11112355, GO:0001533=PMID:9813070} O95171 Sciellin protein 20110516 {GO:0005515=IPI, GO:0005737=ISS, GO:0008544=TAS, GO:0005886=IDA, GO:0030216=IDA, GO:0008270=IEA, GO:0009790=ISS, GO:0001533=TAS} embryo development, epidermis development, keratinocyte differentiation cornified envelope, cytoplasm, plasma membrane protein binding, zinc ion binding Human SCFD1 UniProtKB UniProtKB {GO:0019905=GO_REF:0000024, GO:0005801=PMID:15649705, GO:0001666=GO_REF:0000019, GO:0005886=GO_REF:0000024, GO:0060628=GO_REF:0000024, GO:0006890=GO_REF:0000024, GO:0005798=GO_REF:0000024, GO:0006892=GO_REF:0000024, GO:0009636=PMID:15649705, GO:0015031=GO_REF:0000037, GO:0006904=GO_REF:0000002, GO:0047485=GO_REF:0000019, GO:0032580=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0017119=GO_REF:0000024} Q8WVM8 Sec1 family domain-containing protein 1 protein 20090827 {GO:0019905=ISS, GO:0005801=IDA, GO:0001666=IEA, GO:0005886=ISS, GO:0060628=ISS, GO:0006890=ISS, GO:0005798=ISS, GO:0006892=ISS, GO:0009636=IEP, GO:0015031=IEA, GO:0006904=IEA, GO:0047485=IEA, GO:0032580=IEA, GO:0005789=IEA, GO:0017119=ISS} post-Golgi vesicle-mediated transport, protein transport, regulation of ER to Golgi vesicle-mediated transport, response to hypoxia, response to toxic substance, retrograde vesicle-mediated transport, Golgi to ER, vesicle docking involved in exocytosis Golgi cisterna membrane, Golgi transport complex, Golgi-associated vesicle, cis-Golgi network, endoplasmic reticulum membrane, plasma membrane protein N-terminus binding, syntaxin binding Human UniProtKB:Q62991 SCFD2 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0015031=GO_REF:0000037, GO:0006904=GO_REF:0000002} Q8WU76 Sec1 family domain-containing protein 2 protein 20090826 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND, GO:0015031=IEA, GO:0006904=IEA} biological_process, protein transport, vesicle docking involved in exocytosis cellular_component molecular_function Human SCG2 GOC UniProtKB {GO:0043066=PMID:14970115, GO:0009306=PMID:2745426, GO:0006928=PMID:9473216, GO:0001525=PMID:14970115, GO:0005615=PMID:9473216, GO:0042056=PMID:9473216, GO:0005125=PMID:14970115, GO:0050918=PMID:9473216, GO:0035556=PMID:9473216, GO:0050930=PMID:9473216, GO:0006954=PMID:14970115, GO:0001938=PMID:14970115, GO:0043542=PMID:9473216, GO:0000165=PMID:14970115, GO:0001937=PMID:9473216, GO:0048245=PMID:9473216, GO:0030141=GO_REF:0000002} P13521 Secretogranin-2 protein 20130413 {GO:0043066=IDA, GO:0009306=TAS, GO:0006928=IDA, GO:0001525=IDA, GO:0005615=IDA, GO:0042056=IDA, GO:0005125=IDA, GO:0050918=IDA, GO:0035556=IDA, GO:0050930=IDA, GO:0006954=TAS, GO:0001938=IDA, GO:0043542=TAS, GO:0000165=IDA, GO:0001937=TAS, GO:0048245=IDA, GO:0030141=IEA} MAPK cascade, angiogenesis, cellular component movement, endothelial cell migration, eosinophil chemotaxis, induction of positive chemotaxis, inflammatory response, intracellular signal transduction, negative regulation of apoptotic process, negative regulation of endothelial cell proliferation, positive chemotaxis, positive regulation of endothelial cell proliferation, protein secretion extracellular space, secretory granule chemoattractant activity, cytokine activity Human SCG3 Reactome UniProtKB {GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_21324, GO:0034774=Reactome:REACT_21324, GO:0030658=GO_REF:0000039} Q8WXD2 Secretogranin-3 protein 20121130 {GO:0007596=TAS, GO:0002576=TAS, GO:0030168=TAS, GO:0005576=TAS, GO:0034774=TAS, GO:0030658=IEA} blood coagulation, platelet activation, platelet degranulation extracellular region, secretory granule lumen, transport vesicle membrane Human SCG5 PINC UniProtKB {GO:0005515=PMID:7913882, GO:0004857=GO_REF:0000024, GO:0016486=GO_REF:0000024, GO:0007218=GO_REF:0000037, GO:0046883=GO_REF:0000024, GO:0005576=GO_REF:0000039, GO:0051082=PMID:7913882, GO:0005525=PMID:3134253, GO:0030141=GO_REF:0000024, GO:0006886=GO_REF:0000024} P05408 Neuroendocrine protein 7B2 protein 20030904 {GO:0005515=IPI, GO:0004857=ISS, GO:0016486=ISS, GO:0007218=IEA, GO:0046883=ISS, GO:0005576=IEA, GO:0051082=IDA, GO:0005525=TAS, GO:0030141=ISS, GO:0006886=ISS} intracellular protein transport, neuropeptide signaling pathway, peptide hormone processing, regulation of hormone secretion extracellular region, secretory granule GTP binding, enzyme inhibitor activity, protein binding, unfolded protein binding Human SCGB1A1 PINC UniProtKB {GO:0005791=GO_REF:0000019, GO:0043488=GO_REF:0000019, GO:0007565=PMID:10587371, GO:0007566=PMID:10587371, GO:0042493=GO_REF:0000019, GO:0032714=GO_REF:0000019, GO:0010193=GO_REF:0000019, GO:0032713=GO_REF:0000019, GO:0050727=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0005635=GO_REF:0000019, GO:0034021=GO_REF:0000019, GO:0019834=GO_REF:0000037, GO:0000122=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0071774=GO_REF:0000019, GO:0042130=GO_REF:0000019, GO:0007165=PMID:10587371, GO:0032696=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0009410=GO_REF:0000019, GO:0030141=GO_REF:0000019, GO:0034097=GO_REF:0000019, GO:0032689=GO_REF:0000019} P11684 Uteroglobin protein 20040811 {GO:0005791=IEA, GO:0043488=IEA, GO:0007565=NAS, GO:0007566=TAS, GO:0042493=IEA, GO:0032714=IEA, GO:0010193=IEA, GO:0032713=IEA, GO:0050727=IEA, GO:0051384=IEA, GO:0005635=IEA, GO:0034021=IEA, GO:0019834=IEA, GO:0000122=IEA, GO:0005615=IEA, GO:0071774=IEA, GO:0042130=IEA, GO:0007165=NAS, GO:0032696=IEA, GO:0032496=IEA, GO:0009410=IEA, GO:0030141=IEA, GO:0034097=IEA, GO:0032689=IEA} embryo implantation, female pregnancy, negative regulation of T cell proliferation, negative regulation of interferon-gamma production, negative regulation of interleukin-13 production, negative regulation of interleukin-4 production, negative regulation of interleukin-5 production, negative regulation of transcription from RNA polymerase II promoter, regulation of inflammatory response, regulation of mRNA stability, response to cytokine stimulus, response to drug, response to fibroblast growth factor stimulus, response to glucocorticoid stimulus, response to lipopolysaccharide, response to ozone, response to silicon dioxide, response to xenobiotic stimulus, signal transduction extracellular space, nuclear envelope, rough endoplasmic reticulum, secretory granule phospholipase A2 inhibitor activity Human SCGB1D1 PINC UniProtKB {GO:0005615=PMID:10066439} O95968 Secretoglobin family 1D member 1 protein 20030904 {GO:0005615=TAS} extracellular space Human SCGB1D2 PINC UniProtKB {GO:0005615=PMID:10066439} O95969 Secretoglobin family 1D member 2 protein 20030904 {GO:0005615=TAS} extracellular space Human SCGB2A1 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0005497=GO_REF:0000029} O75556 Mammaglobin-B protein 20061026 {GO:0008150=ND, GO:0005575=ND, GO:0005497=NAS} biological_process cellular_component androgen binding Human SCGB2A2 InterPro UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0005496=GO_REF:0000002} Q6NX70 SCGB2A2 protein protein 20130413 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND, GO:0005496=IEA} biological_process cellular_component molecular_function, steroid binding Human InterPro:IPR003627 SCGB3A1 UniProtKB UniProtKB {GO:0030308=PMID:11481438, GO:0042127=PMID:11481438, GO:0005576=PMID:11481438, GO:0005125=PMID:11481438, GO:0005615=GO_REF:0000037} Q96QR1 Secretoglobin family 3A member 1 protein 20030717 {GO:0030308=NAS, GO:0042127=NAS, GO:0005576=NAS, GO:0005125=NAS, GO:0005615=IEA} negative regulation of cell growth, regulation of cell proliferation extracellular region, extracellular space cytokine activity Human SCGB3A2 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q96PL1 Secretoglobin family 3A member 2 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 SCGN UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0005737=PMID:10811645, GO:0005509=PMID:10811645, GO:0005576=GO_REF:0000039, GO:0030658=GO_REF:0000039} O76038 Secretagogin protein 20010926 {GO:0008150=ND, GO:0005737=NAS, GO:0005509=NAS, GO:0005576=IEA, GO:0030658=IEA} biological_process cytoplasm, extracellular region, transport vesicle membrane calcium ion binding Human SCHIP1 HPA UniProtKB {GO:0005515=PMID:20195357, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0042802=PMID:20195357} Q9P0W5 Schwannomin-interacting protein 1 protein 20080205 {GO:0005515=IPI, GO:0008150=ND, GO:0005737=IDA, GO:0042802=IPI} biological_process cytoplasm identical protein binding, protein binding Human SCIN HPA UniProtKB {GO:0008285=PMID:11568009, GO:0043065=PMID:11568009, GO:0051047=GO_REF:0000024, GO:0005509=GO_REF:0000024, GO:0005546=GO_REF:0000024, GO:0032330=GO_REF:0000024, GO:0003779=GO_REF:0000024, GO:0051693=GO_REF:0000037, GO:0045010=GO_REF:0000024, GO:0051014=PMID:11568009, GO:0005545=PMID:11568009, GO:0005737=GO_REF:0000052, GO:0045654=PMID:11568009, GO:0051015=GO_REF:0000024, GO:0017156=GO_REF:0000024, GO:0001786=GO_REF:0000024, GO:0005856=GO_REF:0000039, GO:0005938=GO_REF:0000024} Q9Y6U3 Adseverin protein 20100326 {GO:0008285=IMP, GO:0043065=IMP, GO:0051047=ISS, GO:0005509=ISS, GO:0005546=ISS, GO:0032330=ISS, GO:0003779=ISS, GO:0051693=IEA, GO:0045010=ISS, GO:0051014=IMP, GO:0005545=TAS, GO:0005737=IDA, GO:0045654=IMP, GO:0051015=ISS, GO:0017156=ISS, GO:0001786=ISS, GO:0005856=IEA, GO:0005938=ISS} actin filament capping, actin filament severing, actin nucleation, calcium ion-dependent exocytosis, negative regulation of cell proliferation, positive regulation of apoptotic process, positive regulation of megakaryocyte differentiation, positive regulation of secretion, regulation of chondrocyte differentiation cell cortex, cytoplasm, cytoskeleton 1-phosphatidylinositol binding, actin binding, actin filament binding, calcium ion binding, phosphatidylinositol-4,5-bisphosphate binding, phosphatidylserine binding Human SCLT1 HPA UniProtKB {GO:0005813=PMID:21399614, GO:0005737=GO_REF:0000052, GO:0045162=GO_REF:0000019, GO:0071439=GO_REF:0000019, GO:0030276=GO_REF:0000019, GO:0045111=GO_REF:0000052, GO:0008022=GO_REF:0000019, GO:0017080=GO_REF:0000019} Q96NL6 Sodium channel and clathrin linker 1 protein 20110516 {GO:0005813=IDA, GO:0005737=IDA, GO:0045162=IEA, GO:0071439=IEA, GO:0030276=IEA, GO:0045111=IDA, GO:0008022=IEA, GO:0017080=IEA} clustering of voltage-gated sodium channels centrosome, clathrin complex, cytoplasm, intermediate filament cytoskeleton clathrin binding, protein C-terminus binding, sodium channel regulator activity Human SCLY PINC UniProtKB {GO:0006520=PMID:10692412, GO:0030170=GO_REF:0000002, GO:0003824=GO_REF:0000002, GO:0009000=GO_REF:0000003, GO:0016740=GO_REF:0000037, GO:0016829=GO_REF:0000038, GO:0005829=GO_REF:0000039} Q96I15 Selenocysteine lyase protein 20090803 {GO:0006520=TAS, GO:0030170=IEA, GO:0003824=IEA, GO:0009000=IEA, GO:0016740=IEA, GO:0016829=IEA, GO:0005829=IEA} cellular amino acid metabolic process cytosol catalytic activity, lyase activity, pyridoxal phosphate binding, selenocysteine lyase activity, transferase activity Human SCMH1 PINC UniProtKB {GO:0006355=GO_REF:0000002, GO:0003700=PMID:10524249, GO:0010369=GO_REF:0000019, GO:0016458=GO_REF:0000024, GO:0006338=GO_REF:0000019, GO:0005634=PMID:10524249, GO:0007283=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0009653=PMID:10524249, GO:0003677=PMID:10524249, GO:0045892=PMID:10524249, GO:0006351=GO_REF:0000037} Q96GD3 Polycomb protein SCMH1 protein 20061107 {GO:0006355=IEA, GO:0003700=TAS, GO:0010369=IEA, GO:0016458=ISS, GO:0006338=IEA, GO:0005634=IC, GO:0007283=IEA, GO:0009952=IEA, GO:0009653=TAS, GO:0003677=TAS, GO:0045892=NAS, GO:0006351=IEA} anatomical structure morphogenesis, anterior/posterior pattern specification, chromatin remodeling, gene silencing, negative regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, spermatogenesis, transcription, DNA-dependent chromocenter, nucleus DNA binding, sequence-specific DNA binding transcription factor activity Human SCML1 PINC UniProtKB {GO:0003700=PMID:9570953, GO:0005634=GO_REF:0000039, GO:0009653=PMID:9570953, GO:0003677=PMID:9570953, GO:0006351=GO_REF:0000037} Q9UN30 Sex comb on midleg-like protein 1 protein 20031119 {GO:0003700=TAS, GO:0005634=IEA, GO:0009653=TAS, GO:0003677=TAS, GO:0006351=IEA} anatomical structure morphogenesis, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity Human SCML2 PINC UniProtKB {GO:0031519=PMID:21282530, GO:0003700=PMID:10331946, GO:0005634=PMID:21282530, GO:0009653=PMID:10331946, GO:0003677=PMID:10331946, GO:0006351=GO_REF:0000037} Q9UQR0 Sex comb on midleg-like protein 2 protein 20031119 {GO:0031519=IDA, GO:0003700=TAS, GO:0005634=IDA, GO:0009653=TAS, GO:0003677=TAS, GO:0006351=IEA} anatomical structure morphogenesis, transcription, DNA-dependent PcG protein complex, nucleus DNA binding, sequence-specific DNA binding transcription factor activity Human SCN10A BHF-UCL UniProtKB {GO:0005248=PMID:9839820, GO:0019233=GO_REF:0000019, GO:0060371=PMID:21041692, GO:0086067=PMID:20062061, GO:0086069=PMID:20062061, GO:0002027=PMID:21041692, GO:0071439=GO_REF:0000019, GO:0055117=PMID:20062061, GO:0042475=GO_REF:0000019, GO:0035725=PMID:9839820, GO:0001518=PMID:9839820, GO:0006814=PMID:9839820, GO:0007600=PMID:9839820} Q9Y5Y9 Sodium channel protein type 10 subunit alpha protein 20120801 {GO:0005248=IDA, GO:0019233=IEA, GO:0060371=IMP, GO:0086067=IMP, GO:0086069=IMP, GO:0002027=IMP, GO:0071439=IEA, GO:0055117=IMP, GO:0042475=IEA, GO:0035725=IDA, GO:0001518=IDA, GO:0006814=TAS, GO:0007600=TAS} AV node cell to bundle of His cell communication, bundle of His cell to Purkinje myocyte communication, odontogenesis of dentin-containing tooth, regulation of atrial cardiac muscle cell membrane depolarization, regulation of cardiac muscle contraction, regulation of heart rate, sensory perception, sensory perception of pain, sodium ion transmembrane transport, sodium ion transport clathrin complex, voltage-gated sodium channel complex voltage-gated sodium channel activity Human SCN1A BHF-UCL UniProtKB {GO:0030018=GO_REF:0000024, GO:0005248=PMID:10742094, GO:0030315=GO_REF:0000019, GO:0019227=GO_REF:0000019, GO:0019228=GO_REF:0000019, GO:0043194=GO_REF:0000019, GO:0033268=GO_REF:0000019, GO:0014704=GO_REF:0000019, GO:0050884=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0007628=GO_REF:0000019, GO:0001518=GO_REF:0000002, GO:0016021=GO_REF:0000029, GO:0006814=PMID:10742094} P35498 Sodium channel protein type 1 subunit alpha protein 20120521 {GO:0030018=ISS, GO:0005248=NAS, GO:0030315=IEA, GO:0019227=IEA, GO:0019228=IEA, GO:0043194=IEA, GO:0033268=IEA, GO:0014704=IEA, GO:0050884=IEA, GO:0043025=IEA, GO:0007628=IEA, GO:0001518=IEA, GO:0016021=NAS, GO:0006814=NAS} adult walking behavior, neuromuscular process controlling posture, neuronal action potential propagation, regulation of action potential in neuron, sodium ion transport T-tubule, Z disc, axon initial segment, integral to membrane, intercalated disc, neuronal cell body, node of Ranvier, voltage-gated sodium channel complex voltage-gated sodium channel activity Human UniProtKB:A2APX6 SCN1B BHF-UCL UniProtKB {GO:0051899=PMID:21051419, GO:0046684=GO_REF:0000019, GO:0021966=GO_REF:0000024, GO:0007268=PMID:9697698, GO:0060307=PMID:17884088, GO:0086091=PMID:19808477, GO:0060048=PMID:19808477, GO:0019227=GO_REF:0000024, GO:0060371=PMID:19808477, GO:0040011=GO_REF:0000024, GO:0007411=GO_REF:0000024, GO:0010765=PMID:19808477, GO:0086002=PMID:19808477, GO:0035725=PMID:19808477, GO:0001518=PMID:21051419, GO:0007155=GO_REF:0000037, GO:0006814=GO_REF:0000002, GO:0061337=GO_REF:0000024, GO:0086006=PMID:19808477, GO:0086047=PMID:18464934, GO:0005248=PMID:19808477, GO:0005576=GO_REF:0000039, GO:0086062=PMID:18464934, GO:0033268=GO_REF:0000024, GO:0019871=PMID:17884088, GO:0086012=PMID:17884088, GO:0017080=GO_REF:0000002} Q07699 Sodium channel subunit beta-1 protein 20120530 {GO:0051899=IDA, GO:0046684=IEA, GO:0021966=ISS, GO:0007268=TAS, GO:0060307=ISS, GO:0086091=IMP, GO:0060048=IMP, GO:0019227=ISS, GO:0060371=IMP, GO:0040011=ISS, GO:0007411=ISS, GO:0010765=IDA, GO:0086002=IMP, GO:0035725=IDA, GO:0001518=IDA, GO:0007155=IEA, GO:0006814=IEA, GO:0061337=ISS, GO:0086006=IMP, GO:0086047=IMP, GO:0005248=IDA, GO:0005576=IEA, GO:0086062=IMP, GO:0033268=ISS, GO:0019871=ISS, GO:0086012=ISS, GO:0017080=IEA} axon guidance, cardiac conduction, cardiac muscle contraction, cell adhesion, corticospinal neuron axon guidance, locomotion, membrane depolarization, membrane depolarization involved in regulation of Purkinje myocyte cell action potential, membrane depolarization involved in regulation of cardiac muscle cell action potential, neuronal action potential propagation, positive regulation of sodium ion transport, regulation of atrial cardiac muscle cell membrane depolarization, regulation of cardiac muscle cell action potential involved in contraction, regulation of heart rate by cardiac conduction, regulation of ventricular cardiac muscle cell membrane repolarization, response to pyrethroid, sodium ion transmembrane transport, sodium ion transport, synaptic transmission extracellular region, node of Ranvier, voltage-gated sodium channel complex sodium channel inhibitor activity, sodium channel regulator activity, voltage-gated sodium channel activity, voltage-gated sodium channel activity involved in regulation of Purkinje myocyte action potential, voltage-gated sodium channel activity involved in regulation of cardiac muscle cell action potential Human SCN2A BHF-UCL UniProtKB {GO:0030424=PMID:16652168, GO:0042552=GO_REF:0000024, GO:0005248=GO_REF:0000019, GO:0006915=GO_REF:0000019, GO:0030315=GO_REF:0000019, GO:0033270=GO_REF:0000019, GO:0033268=GO_REF:0000024, GO:0014704=GO_REF:0000019, GO:0005887=PMID:1325650, GO:0001518=GO_REF:0000002, GO:0016021=GO_REF:0000038, GO:0006814=PMID:1325650, GO:0005216=GO_REF:0000002} Q99250 Sodium channel protein type 2 subunit alpha protein 20091120 {GO:0030424=TAS, GO:0042552=ISS, GO:0005248=IEA, GO:0006915=IEA, GO:0030315=IEA, GO:0033270=IEA, GO:0033268=ISS, GO:0014704=IEA, GO:0005887=TAS, GO:0001518=IEA, GO:0016021=IEA, GO:0006814=TAS, GO:0005216=IEA} apoptotic process, myelination, sodium ion transport T-tubule, axon, integral to membrane, integral to plasma membrane, intercalated disc, node of Ranvier, paranode region of axon, voltage-gated sodium channel complex ion channel activity, voltage-gated sodium channel activity Human SCN2B BHF-UCL UniProtKB {GO:0060371=PMID:19808477, GO:0046684=GO_REF:0000019, GO:0086002=PMID:19808477, GO:0007268=PMID:9295116, GO:0035725=PMID:19808477, GO:0001518=PMID:19808477, GO:0086091=PMID:19808477, GO:0086006=PMID:19808477, GO:0060048=PMID:19808477, GO:0007399=GO_REF:0000019} O60939 Sodium channel subunit beta-2 protein 20120525 {GO:0060371=IMP, GO:0046684=IEA, GO:0086002=IMP, GO:0007268=TAS, GO:0035725=IDA, GO:0001518=IDA, GO:0086091=IMP, GO:0086006=IMP, GO:0060048=IMP, GO:0007399=IEA} cardiac muscle contraction, nervous system development, regulation of atrial cardiac muscle cell membrane depolarization, regulation of cardiac muscle cell action potential involved in contraction, regulation of heart rate by cardiac conduction, response to pyrethroid, sodium ion transmembrane transport, synaptic transmission voltage-gated sodium channel complex voltage-gated sodium channel activity involved in regulation of cardiac muscle cell action potential Human SCN3A UniProtKB UniProtKB {GO:0005737=GO_REF:0000019, GO:0005248=PMID:9589372, GO:0001518=GO_REF:0000029, GO:0016021=GO_REF:0000038, GO:0006814=PMID:9589372, GO:0005216=GO_REF:0000002} Q9NY46 Sodium channel protein type 3 subunit alpha protein 20021104 {GO:0005737=IEA, GO:0005248=NAS, GO:0001518=NAS, GO:0016021=IEA, GO:0006814=NAS, GO:0005216=IEA} sodium ion transport cytoplasm, integral to membrane, voltage-gated sodium channel complex ion channel activity, voltage-gated sodium channel activity Human SCN3B BHF-UCL UniProtKB {GO:0030018=GO_REF:0000024, GO:0051899=PMID:21051419, GO:0005886=GO_REF:0000054, GO:0086010=PMID:20226894, GO:0086070=GO_REF:0000024, GO:0086091=PMID:20042427, GO:0060048=PMID:20042427, GO:0060371=PMID:21051419, GO:0060373=PMID:20042427, GO:0007411=Reactome:REACT_18266, GO:0010765=PMID:20042427, GO:0086002=PMID:21051419, GO:0035725=PMID:20226894, GO:0001518=PMID:20042427, GO:0006814=PMID:10688874, GO:0086006=PMID:20042427, GO:0086005=PMID:20042427, GO:0005248=PMID:10688874, GO:0072659=PMID:20042427, GO:0019233=GO_REF:0000019, GO:0007399=GO_REF:0000019, GO:0044325=PMID:20042427, GO:0086014=PMID:21051419, GO:0086012=PMID:21051419, GO:0016021=PMID:10688874, GO:0010460=GO_REF:0000024, GO:0017080=PMID:20226894} Q9NY72 Sodium channel subunit beta-3 protein 20120608 {GO:0030018=ISS, GO:0051899=IDA, GO:0005886=IDA, GO:0086010=IDA, GO:0086070=ISS, GO:0086091=IMP, GO:0060048=IMP, GO:0060371=IMP, GO:0060373=IMP, GO:0007411=TAS, GO:0010765=IDA, GO:0086002=IMP, GO:0035725=IDA, GO:0001518=IDA, GO:0006814=NAS, GO:0086006=IDA, GO:0086005=IMP, GO:0005248=NAS, GO:0072659=IMP, GO:0019233=IEA, GO:0007399=IEA, GO:0044325=IPI, GO:0086014=IMP, GO:0086012=IMP, GO:0016021=NAS, GO:0010460=ISS, GO:0017080=IDA} SA node cell to atrial cardiac muscle cell communication, axon guidance, cardiac muscle contraction, membrane depolarization, membrane depolarization involved in regulation of action potential, membrane depolarization involved in regulation of cardiac muscle cell action potential, nervous system development, positive regulation of heart rate, positive regulation of sodium ion transport, protein localization to plasma membrane, regulation of atrial cardiac muscle cell action potential, regulation of atrial cardiac muscle cell membrane depolarization, regulation of cardiac muscle cell action potential involved in contraction, regulation of heart rate by cardiac conduction, regulation of ventricular cardiac muscle cell action potential, regulation of ventricular cardiac muscle cell membrane depolarization, sensory perception of pain, sodium ion transmembrane transport, sodium ion transport Z disc, integral to membrane, plasma membrane, voltage-gated sodium channel complex ion channel binding, sodium channel regulator activity, voltage-gated sodium channel activity, voltage-gated sodium channel activity involved in regulation of cardiac muscle cell action potential Human UniProtKB:Q8BHK2 SCN4A PINC UniProtKB {GO:0006936=PMID:1338909, GO:0005887=PMID:1659948, GO:0005248=GO_REF:0000019, GO:0001518=GO_REF:0000002, GO:0006814=PMID:10218481} P35499 Sodium channel protein type 4 subunit alpha protein 20030904 {GO:0006936=TAS, GO:0005887=TAS, GO:0005248=IEA, GO:0001518=IEA, GO:0006814=TAS} muscle contraction, sodium ion transport integral to plasma membrane, voltage-gated sodium channel complex voltage-gated sodium channel activity Human SCN4B BHF-UCL UniProtKB {GO:0005248=PMID:12930796, GO:0060307=PMID:17592081, GO:2000649=PMID:17592081, GO:0086091=PMID:17592081, GO:0060048=PMID:17592081, GO:0044325=PMID:17592081, GO:0086067=PMID:17592081, GO:0014704=GO_REF:0000024, GO:0010765=PMID:17592081, GO:0086002=PMID:17592081, GO:0035725=PMID:20226894, GO:0001518=PMID:17592081, GO:0086012=PMID:17592081, GO:0006814=PMID:12930796, GO:0086006=PMID:17592081, GO:0017080=PMID:17592081} Q8IWT1 Sodium channel subunit beta-4 protein 20120531 {GO:0005248=IDA, GO:0060307=IMP, GO:2000649=IDA, GO:0086091=IMP, GO:0060048=IMP, GO:0044325=IPI, GO:0086067=IMP, GO:0014704=ISS, GO:0010765=IDA, GO:0086002=IMP, GO:0035725=IDA, GO:0001518=IDA, GO:0086012=IMP, GO:0006814=IDA, GO:0086006=IMP, GO:0017080=IDA} AV node cell to bundle of His cell communication, cardiac muscle contraction, membrane depolarization involved in regulation of cardiac muscle cell action potential, positive regulation of sodium ion transport, regulation of cardiac muscle cell action potential involved in contraction, regulation of heart rate by cardiac conduction, regulation of sodium ion transmembrane transporter activity, regulation of ventricular cardiac muscle cell membrane repolarization, sodium ion transmembrane transport, sodium ion transport intercalated disc, voltage-gated sodium channel complex ion channel binding, sodium channel regulator activity, voltage-gated sodium channel activity, voltage-gated sodium channel activity involved in regulation of cardiac muscle cell action potential Human SCN5A BHF-UCL UniProtKB {GO:0005515=PMID:18184654, GO:0014070=GO_REF:0000019, GO:0005516=PMID:21167176, GO:0086010=PMID:18065446, GO:0086070=PMID:18616619, GO:0060307=PMID:7889574, GO:0060048=PMID:18065446, GO:0060371=PMID:22247482, GO:0086067=PMID:18616619, GO:0060373=PMID:18065446, GO:0086069=PMID:18065446, GO:0060372=PMID:19167345, GO:0010765=PMID:18065446, GO:0086002=PMID:21895525, GO:0001518=PMID:20042427, GO:0045760=GO_REF:0000024, GO:0086006=PMID:18616619, GO:0086004=PMID:22529811, GO:0086005=PMID:18065446, GO:0050679=GO_REF:0000024, GO:0009986=PMID:19666841, GO:0003360=GO_REF:0000024, GO:0030506=PMID:15579534, GO:0021549=GO_REF:0000024, GO:0014894=GO_REF:0000024, GO:0086063=GO_REF:0000019, GO:0044325=PMID:17592081, GO:0002027=PMID:18616619, GO:0086012=PMID:21895525, GO:0019899=PMID:19666841, GO:0003231=GO_REF:0000024, GO:0051899=PMID:21051419, GO:0005886=PMID:22529811, GO:0005783=PMID:22529811, GO:0086091=PMID:21895525, GO:0021537=GO_REF:0000024, GO:0014704=PMID:15579534, GO:0097110=PMID:17060380, GO:0071277=PMID:19074138, GO:0042475=GO_REF:0000024, GO:0035725=PMID:14500339, GO:0006814=PMID:19074138, GO:0086046=GO_REF:0000024, GO:0005248=PMID:19808477, GO:0030315=PMID:15579534, GO:0034706=GO_REF:0000019, GO:0042383=PMID:17060380, GO:0005901=PMID:17060380, GO:0016021=PMID:19074138} Q14524 Sodium channel protein type 5 subunit alpha protein 20120608 {GO:0005515=IPI, GO:0014070=IEA, GO:0005516=IPI, GO:0086010=IDA, GO:0086070=IMP, GO:0060307=IMP, GO:0060048=IMP, GO:0060371=IMP, GO:0086067=IMP, GO:0060373=IMP, GO:0086069=IMP, GO:0060372=IMP, GO:0010765=IDA, GO:0086002=IMP, GO:0001518=IDA, GO:0045760=ISS, GO:0086006=IMP, GO:0086004=IMP, GO:0086005=IMP, GO:0050679=ISS, GO:0009986=IDA, GO:0003360=ISS, GO:0030506=IDA, GO:0021549=ISS, GO:0014894=ISS, GO:0086063=IEA, GO:0044325=IPI, GO:0002027=IMP, GO:0086012=IMP, GO:0019899=IPI, GO:0003231=ISS, GO:0051899=IDA, GO:0005886=IDA, GO:0005783=IDA, GO:0086091=IMP, GO:0021537=ISS, GO:0014704=IDA, GO:0097110=IPI, GO:0071277=IDA, GO:0042475=ISS, GO:0035725=IDA, GO:0006814=IDA, GO:0086046=ISS, GO:0005248=IDA, GO:0030315=IDA, GO:0034706=IEA, GO:0042383=IDA, GO:0005901=TAS, GO:0016021=IDA} AV node cell to bundle of His cell communication, SA node cell to atrial cardiac muscle cell communication, brainstem development, bundle of His cell to Purkinje myocyte communication, cardiac muscle contraction, cardiac ventricle development, cellular response to calcium ion, cerebellum development, membrane depolarization, membrane depolarization involved in regulation of SA node cell action potential, membrane depolarization involved in regulation of action potential, membrane depolarization involved in regulation of cardiac muscle cell action potential, odontogenesis of dentin-containing tooth, positive regulation of action potential, positive regulation of epithelial cell proliferation, positive regulation of sodium ion transport, regulation of atrial cardiac muscle cell membrane depolarization, regulation of atrial cardiac muscle cell membrane repolarization, regulation of cardiac muscle cell action potential involved in contraction, regulation of cardiac muscle cell contraction, regulation of heart rate, regulation of heart rate by cardiac conduction, regulation of ventricular cardiac muscle cell action potential, regulation of ventricular cardiac muscle cell membrane depolarization, regulation of ventricular cardiac muscle cell membrane repolarization, response to denervation involved in regulation of muscle adaptation, response to organic cyclic compound, sodium ion transmembrane transport, sodium ion transport, telencephalon development T-tubule, caveola, cell surface, endoplasmic reticulum, integral to membrane, intercalated disc, plasma membrane, sarcolemma, sodium channel complex, voltage-gated sodium channel complex ankyrin binding, calmodulin binding, enzyme binding, ion channel binding, protein binding, scaffold protein binding, voltage-gated sodium channel activity, voltage-gated sodium channel activity involved in regulation of SA node cell action potential, voltage-gated sodium channel activity involved in regulation of cardiac muscle cell action potential Human SCN8A BHF-UCL UniProtKB {GO:0030018=GO_REF:0000024, GO:0042552=GO_REF:0000024, GO:0007605=GO_REF:0000019, GO:0005248=PMID:21078353, GO:0009636=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0030425=GO_REF:0000019, GO:0007399=PMID:9828131, GO:0050905=GO_REF:0000019, GO:0043194=GO_REF:0000024, GO:0033268=GO_REF:0000024, GO:0007517=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0007422=GO_REF:0000024, GO:0007628=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0016023=GO_REF:0000039, GO:0001518=PMID:9828131, GO:0016021=PMID:9828131, GO:0006814=PMID:9828131, GO:0005216=GO_REF:0000002} Q9UQD0 Sodium channel protein type 8 subunit alpha protein 20120607 {GO:0030018=ISS, GO:0042552=ISS, GO:0007605=IEA, GO:0005248=IDA, GO:0009636=IEA, GO:0005524=IEA, GO:0030425=IEA, GO:0007399=TAS, GO:0050905=IEA, GO:0043194=ISS, GO:0033268=ISS, GO:0007517=IEA, GO:0007411=TAS, GO:0007422=ISS, GO:0007628=IEA, GO:0043025=IEA, GO:0016023=IEA, GO:0001518=IC, GO:0016021=TAS, GO:0006814=NAS, GO:0005216=IEA} adult walking behavior, axon guidance, muscle organ development, myelination, nervous system development, neuromuscular process, peripheral nervous system development, response to toxic substance, sensory perception of sound, sodium ion transport Z disc, axon initial segment, cytoplasmic membrane-bounded vesicle, dendrite, integral to membrane, neuronal cell body, node of Ranvier, voltage-gated sodium channel complex ATP binding, ion channel activity, voltage-gated sodium channel activity Human UniProtKB:O88420 SCN9A PINC UniProtKB {GO:0006954=GO_REF:0000019, GO:0005248=GO_REF:0000019, GO:0009636=GO_REF:0000019, GO:0001518=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0006814=PMID:7720699, GO:0031402=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0048266=GO_REF:0000019, GO:0005216=GO_REF:0000002, GO:0019228=GO_REF:0000019} Q15858 Sodium channel protein type 9 subunit alpha protein 20030904 {GO:0006954=IEA, GO:0005248=IEA, GO:0009636=IEA, GO:0001518=IEA, GO:0016021=IEA, GO:0006814=TAS, GO:0031402=IEA, GO:0009791=IEA, GO:0048266=IEA, GO:0005216=IEA, GO:0019228=IEA} behavioral response to pain, inflammatory response, post-embryonic development, regulation of action potential in neuron, response to toxic substance, sodium ion transport integral to membrane, voltage-gated sodium channel complex ion channel activity, sodium ion binding, voltage-gated sodium channel activity Human SCNM1 UniProtKB UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0016607=GO_REF:0000039, GO:0046872=GO_REF:0000037} Q9BWG6 Sodium channel modifier 1 protein 20130413 {GO:0008380=IEA, GO:0006397=IEA, GO:0016607=IEA, GO:0046872=IEA} RNA splicing, mRNA processing nuclear speck metal ion binding Human UniProtKB-SubCell:SL-0186 SCNN1A BHF-UCL UniProtKB {GO:0005515=PMID:22493497, GO:0007588=PMID:8589714, GO:0005886=Reactome:REACT_160256, GO:0005272=GO_REF:0000038, GO:0050699=PMID:10642508, GO:0034706=GO_REF:0000019, GO:0003779=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0015280=GO_REF:0000019, GO:0016324=GO_REF:0000039, GO:0034220=Reactome:REACT_25300, GO:0050909=GO_REF:0000037, GO:0016021=GO_REF:0000038, GO:0030864=GO_REF:0000019, GO:0006814=PMID:8589714, GO:0009897=GO_REF:0000019, GO:0050896=GO_REF:0000037} P37088 Amiloride-sensitive sodium channel subunit alpha protein 20081003 {GO:0005515=IPI, GO:0007588=TAS, GO:0005886=TAS, GO:0005272=IEA, GO:0050699=IPI, GO:0034706=IEA, GO:0003779=IEA, GO:0055085=TAS, GO:0015280=IEA, GO:0016324=IEA, GO:0034220=TAS, GO:0050909=IEA, GO:0016021=IEA, GO:0030864=IEA, GO:0006814=TAS, GO:0009897=IEA, GO:0050896=IEA} excretion, ion transmembrane transport, response to stimulus, sensory perception of taste, sodium ion transport, transmembrane transport apical plasma membrane, cortical actin cytoskeleton, external side of plasma membrane, integral to membrane, plasma membrane, sodium channel complex WW domain binding, actin binding, ligand-gated sodium channel activity, protein binding, sodium channel activity Human UniProtKB:P46934 SCNN1B BHF-UCL UniProtKB {GO:0005515=PMID:22493497, GO:0007588=PMID:9118951, GO:0005886=Reactome:REACT_160256, GO:0005272=GO_REF:0000038, GO:0050699=PMID:10642508, GO:0034706=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0015280=GO_REF:0000019, GO:0016324=GO_REF:0000039, GO:0034220=Reactome:REACT_25300, GO:0050909=GO_REF:0000037, GO:0016021=GO_REF:0000038, GO:0006814=PMID:8521520, GO:0050896=GO_REF:0000037, GO:0009897=GO_REF:0000019} P51168 Amiloride-sensitive sodium channel subunit beta protein 20081003 {GO:0005515=IPI, GO:0007588=TAS, GO:0005886=TAS, GO:0005272=IEA, GO:0050699=IPI, GO:0034706=IEA, GO:0055085=TAS, GO:0015280=IEA, GO:0016324=IEA, GO:0034220=TAS, GO:0050909=IEA, GO:0016021=IEA, GO:0006814=TAS, GO:0050896=IEA, GO:0009897=IEA} excretion, ion transmembrane transport, response to stimulus, sensory perception of taste, sodium ion transport, transmembrane transport apical plasma membrane, external side of plasma membrane, integral to membrane, plasma membrane, sodium channel complex WW domain binding, ligand-gated sodium channel activity, protein binding, sodium channel activity Human UniProtKB:P46934 SCNN1D IntAct UniProtKB {GO:0005515=PMID:14645214, GO:0015280=GO_REF:0000002, GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_160256, GO:0050909=GO_REF:0000037, GO:0005272=GO_REF:0000038, GO:0016021=GO_REF:0000037, GO:0006814=PMID:7499195, GO:0055085=Reactome:REACT_15518, GO:0050896=GO_REF:0000037} P51172 Amiloride-sensitive sodium channel subunit delta protein 20130415 {GO:0005515=IPI, GO:0015280=IEA, GO:0034220=TAS, GO:0005886=TAS, GO:0050909=IEA, GO:0005272=IEA, GO:0016021=IEA, GO:0006814=TAS, GO:0055085=TAS, GO:0050896=IEA} ion transmembrane transport, response to stimulus, sensory perception of taste, sodium ion transport, transmembrane transport integral to membrane, plasma membrane ligand-gated sodium channel activity, protein binding, sodium channel activity Human UniProtKB:Q8N668 SCNN1G BHF-UCL UniProtKB {GO:0005515=PMID:22493497, GO:0007588=PMID:8640238, GO:0005886=Reactome:REACT_160256, GO:0005272=PMID:8521520, GO:0050699=PMID:10642508, GO:0034706=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0015280=GO_REF:0000019, GO:0016324=GO_REF:0000039, GO:0034220=Reactome:REACT_25300, GO:0050909=GO_REF:0000037, GO:0005887=PMID:8640238, GO:0006814=PMID:8521520, GO:0050896=GO_REF:0000037, GO:0009897=GO_REF:0000019} P51170 Amiloride-sensitive sodium channel subunit gamma protein 20081003 {GO:0005515=IPI, GO:0007588=TAS, GO:0005886=TAS, GO:0005272=TAS, GO:0050699=IPI, GO:0034706=IEA, GO:0055085=TAS, GO:0015280=IEA, GO:0016324=IEA, GO:0034220=TAS, GO:0050909=IEA, GO:0005887=TAS, GO:0006814=TAS, GO:0050896=IEA, GO:0009897=IEA} excretion, ion transmembrane transport, response to stimulus, sensory perception of taste, sodium ion transport, transmembrane transport apical plasma membrane, external side of plasma membrane, integral to plasma membrane, plasma membrane, sodium channel complex WW domain binding, ligand-gated sodium channel activity, protein binding, sodium channel activity Human UniProtKB:P46934 SCO1 PINC UniProtKB {GO:0005739=PMID:9878253, GO:0006878=GO_REF:0000002, GO:0008535=GO_REF:0000002, GO:0005507=GO_REF:0000002, GO:0005743=GO_REF:0000002, GO:0006091=PMID:9878253, GO:0006825=GO_REF:0000002} O75880 Protein SCO1 homolog, mitochondrial protein 20030904 {GO:0005739=TAS, GO:0006878=IEA, GO:0008535=IEA, GO:0005507=IEA, GO:0005743=IEA, GO:0006091=TAS, GO:0006825=IEA} cellular copper ion homeostasis, copper ion transport, generation of precursor metabolites and energy, respiratory chain complex IV assembly mitochondrial inner membrane, mitochondrion copper ion binding Human SCO2 UniProtKB UniProtKB {GO:0022904=GO_REF:0000019, GO:0005739=PMID:10545952, GO:0014823=GO_REF:0000019, GO:0006878=GO_REF:0000002, GO:0055070=GO_REF:0000019, GO:0008535=GO_REF:0000019, GO:0005507=PMID:10545952, GO:0005743=GO_REF:0000002, GO:0003012=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0006825=GO_REF:0000002, GO:0055114=PMID:10545952} O43819 Protein SCO2 homolog, mitochondrial protein 20020606 {GO:0022904=IEA, GO:0005739=TAS, GO:0014823=IEA, GO:0006878=IEA, GO:0055070=IEA, GO:0008535=IEA, GO:0005507=NAS, GO:0005743=IEA, GO:0003012=IEA, GO:0001701=IEA, GO:0006825=IEA, GO:0055114=TAS} cellular copper ion homeostasis, copper ion homeostasis, copper ion transport, in utero embryonic development, muscle system process, oxidation-reduction process, respiratory chain complex IV assembly, respiratory electron transport chain, response to activity mitochondrial inner membrane, mitochondrion copper ion binding Human SCOC BHF-UCL UniProtKB {GO:0005802=PMID:22354037, GO:0005515=PMID:22354037, GO:0000139=GO_REF:0000039, GO:0005768=PMID:22354037, GO:0016239=PMID:22354037, GO:0005829=GO_REF:0000039} Q9UIL1 Short coiled-coil protein protein 20120531 {GO:0005802=IDA, GO:0005515=IPI, GO:0000139=IEA, GO:0005768=IDA, GO:0016239=IDA, GO:0005829=IEA} positive regulation of macroautophagy Golgi membrane, cytosol, endosome, trans-Golgi network protein binding Human UniProtKB:Q9P2Y5 SCP2 HPA UniProtKB {GO:0005515=PMID:15182174, GO:0016747=GO_REF:0000002, GO:0005782=Reactome:REACT_121001, GO:0006699=Reactome:REACT_11054, GO:0033814=GO_REF:0000003, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0043231=GO_REF:0000052, GO:0005739=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0032934=GO_REF:0000002, GO:0015485=PMID:18465878, GO:1901373=PMID:15449949, GO:0007031=GO_REF:0000019, GO:0008206=Reactome:REACT_11040, GO:0032385=PMID:15449949, GO:0044255=Reactome:REACT_16957, GO:0005777=PMID:21375735, GO:0005102=PMID:20178365, GO:0005730=GO_REF:0000052, GO:0036109=Reactome:REACT_121147, GO:0033559=Reactome:REACT_121284, GO:0043234=PMID:19584060, GO:0006869=GO_REF:0000037, GO:0033540=Reactome:REACT_17017} P22307 Non-specific lipid-transfer protein protein 20111111 {GO:0005515=IPI, GO:0016747=IEA, GO:0005782=TAS, GO:0006699=TAS, GO:0033814=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0043231=IDA, GO:0005739=IEA, GO:0005737=IDA, GO:0032934=IEA, GO:0015485=IDA, GO:1901373=IDA, GO:0007031=IEA, GO:0008206=TAS, GO:0032385=IDA, GO:0044255=TAS, GO:0005777=IDA, GO:0005102=IPI, GO:0005730=IDA, GO:0036109=TAS, GO:0033559=TAS, GO:0043234=IDA, GO:0006869=IEA, GO:0033540=TAS} alpha-linolenic acid metabolic process, bile acid biosynthetic process, bile acid metabolic process, cellular lipid metabolic process, fatty acid beta-oxidation using acyl-CoA oxidase, lipid hydroperoxide transport, lipid transport, peroxisome organization, positive regulation of intracellular cholesterol transport, small molecule metabolic process, unsaturated fatty acid metabolic process cytoplasm, intracellular membrane-bounded organelle, mitochondrion, nucleolus, nucleus, peroxisomal matrix, peroxisome, protein complex cholesterol binding, propanoyl-CoA C-acyltransferase activity, protein binding, receptor binding, sterol binding, transferase activity, transferring acyl groups other than amino-acyl groups Human SCPEP1 UniProtKB UniProtKB {GO:0004185=GO_REF:0000002, GO:0042573=GO_REF:0000019, GO:0006508=GO_REF:0000037, GO:0005576=GO_REF:0000039, GO:0005829=GO_REF:0000019} Q9HB40 Retinoid-inducible serine carboxypeptidase protein 20130413 {GO:0004185=IEA, GO:0042573=IEA, GO:0006508=IEA, GO:0005576=IEA, GO:0005829=IEA} proteolysis, retinoic acid metabolic process cytosol, extracellular region serine-type carboxypeptidase activity Human UniProtKB-SubCell:SL-0243 SCRIB BHF-UCL UniProtKB {GO:0005515=PMID:16611247, GO:0016080=GO_REF:0000019, GO:0005886=PMID:16611247, GO:0008283=PMID:16965391, GO:0035089=PMID:19041750, GO:0034750=PMID:16611247, GO:0016323=GO_REF:0000019, GO:0016337=PMID:16344308, GO:0005913=PMID:16965391, GO:0008105=GO_REF:0000019, GO:0005911=PMID:15649318, GO:0045211=PMID:15182672, GO:0001921=PMID:15775968, GO:0031252=PMID:18716323, GO:0060603=GO_REF:0000024, GO:0035748=GO_REF:0000019, GO:0043065=PMID:19041750, GO:0001843=PMID:22095531, GO:0060561=PMID:19041750, GO:0048488=GO_REF:0000019, GO:0032863=PMID:19041750, GO:0050918=PMID:18716323, GO:0042734=PMID:15182672, GO:0016477=PMID:18716323, GO:0045930=PMID:16965391, GO:0019048=GO_REF:0000037, GO:0071896=PMID:16611247, GO:0042060=GO_REF:0000019} Q14160 Protein scribble homolog protein 20100930 {GO:0005515=IPI, GO:0016080=IEA, GO:0005886=IDA, GO:0008283=IDA, GO:0035089=IMP, GO:0034750=IDA, GO:0016323=IEA, GO:0016337=IGI, GO:0005913=IDA, GO:0008105=IEA, GO:0005911=IDA, GO:0045211=IDA, GO:0001921=IMP, GO:0031252=IDA, GO:0060603=ISS, GO:0035748=IEA, GO:0043065=IMP, GO:0001843=IMP, GO:0060561=IMP, GO:0048488=IEA, GO:0032863=IMP, GO:0050918=IMP, GO:0042734=IDA, GO:0016477=IMP, GO:0045930=IDA, GO:0019048=IEA, GO:0071896=IMP, GO:0042060=IEA} activation of Rac GTPase activity, apoptotic process involved in morphogenesis, asymmetric protein localization, cell migration, cell proliferation, cell-cell adhesion, establishment of apical/basal cell polarity, mammary gland duct morphogenesis, negative regulation of mitotic cell cycle, neural tube closure, positive chemotaxis, positive regulation of apoptotic process, positive regulation of receptor recycling, protein localization to adherens junction, synaptic vesicle endocytosis, synaptic vesicle targeting, virus-host interaction, wound healing Scrib-APC-beta-catenin complex, basolateral plasma membrane, cell leading edge, cell-cell adherens junction, cell-cell junction, myelin sheath abaxonal region, plasma membrane, postsynaptic membrane, presynaptic membrane protein binding Human SCRN1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0031965=PMID:10942595, GO:0005737=GO_REF:0000039, GO:0006508=GO_REF:0000002, GO:0005634=PMID:10942595, GO:0006887=GO_REF:0000024, GO:0016805=GO_REF:0000002} Q12765 Secernin-1 protein 20041006 {GO:0003674=ND, GO:0031965=IDA, GO:0005737=IEA, GO:0006508=IEA, GO:0005634=IDA, GO:0006887=ISS, GO:0016805=IEA} exocytosis, proteolysis cytoplasm, nuclear membrane, nucleus dipeptidase activity, molecular_function Human UniProtKB:P83939 SCRN2 InterPro UniProtKB {GO:0006508=GO_REF:0000002, GO:0016805=GO_REF:0000002} Q96FV2 Secernin-2 protein 20130413 {GO:0006508=IEA, GO:0016805=IEA} proteolysis dipeptidase activity Human InterPro:IPR005322 SCRN3 InterPro UniProtKB {GO:0006508=GO_REF:0000002, GO:0016805=GO_REF:0000002} Q0VDG4 Secernin-3 protein 20130413 {GO:0006508=IEA, GO:0016805=IEA} proteolysis dipeptidase activity Human InterPro:IPR005322 SCT Reactome UniProtKB {GO:0005179=PMID:11060443, GO:0005576=Reactome:REACT_22268, GO:0005575=GO_REF:0000015, GO:0030157=PMID:11060443} P09683 Secretin protein 20090511 {GO:0005179=NAS, GO:0005576=TAS, GO:0005575=ND, GO:0030157=NAS} pancreatic juice secretion cellular_component, extracellular region hormone activity Human SCTR Reactome UniProtKB {GO:0007588=PMID:7612008, GO:0005881=PMID:23264731, GO:0015055=PMID:7612008, GO:0005886=Reactome:REACT_22268, GO:0007186=PMID:7612008, GO:0005887=PMID:7612008, GO:0007586=PMID:7612008} P47872 Secretin receptor protein 20090511 {GO:0007588=TAS, GO:0005881=IDA, GO:0015055=TAS, GO:0005886=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0007586=TAS} G-protein coupled receptor signaling pathway, digestion, excretion cytoplasmic microtubule, integral to plasma membrane, plasma membrane secretin receptor activity Human SCUBE1 MGI UniProtKB {GO:0046982=PMID:12270931, GO:0009986=PMID:12270931, GO:0005509=PMID:12270931, GO:0009791=PMID:12270931, GO:0005615=PMID:12270931, GO:0007512=PMID:12270931, GO:0042802=PMID:12270931, GO:0006954=PMID:12270931, GO:0007596=PMID:12270931, GO:0051260=PMID:12270931, GO:0045446=PMID:12270931, GO:0009897=PMID:12270931, GO:0019897=PMID:12270931} Q8IWY4 Signal peptide, CUB and EGF-like domain-containing protein 1 protein 20060112 {GO:0046982=IDA, GO:0009986=IDA, GO:0005509=TAS, GO:0009791=NAS, GO:0005615=IDA, GO:0007512=NAS, GO:0042802=IDA, GO:0006954=NAS, GO:0007596=NAS, GO:0051260=IPI, GO:0045446=NAS, GO:0009897=IDA, GO:0019897=IDA} adult heart development, blood coagulation, endothelial cell differentiation, inflammatory response, post-embryonic development, protein homooligomerization cell surface, external side of plasma membrane, extracellular space, extrinsic to plasma membrane calcium ion binding, identical protein binding, protein heterodimerization activity Human SCUBE2 UniProtKB UniProtKB {GO:0005509=GO_REF:0000002, GO:0005576=GO_REF:0000039} Q9NQ36 Signal peptide, CUB and EGF-like domain-containing protein 2 protein 20130413 {GO:0005509=IEA, GO:0005576=IEA} extracellular region calcium ion binding Human UniProtKB-SubCell:SL-0243 SCUBE3 IntAct UniProtKB {GO:0005515=PMID:21441952, GO:0009986=PMID:15234972, GO:0005509=GO_REF:0000002, GO:0051260=PMID:15234972, GO:0005576=GO_REF:0000039, GO:0051291=PMID:15234972} Q8IX30 Signal peptide, CUB and EGF-like domain-containing protein 3 protein 20130415 {GO:0005515=IPI, GO:0009986=IDA, GO:0005509=IEA, GO:0051260=IDA, GO:0005576=IEA, GO:0051291=IPI} protein heterooligomerization, protein homooligomerization cell surface, extracellular region calcium ion binding, protein binding Human UniProtKB:P37173 SCXA UniProtKB UniProtKB {GO:0008284=GO_REF:0000024, GO:0005634=PMID:10775504, GO:0003188=GO_REF:0000024, GO:0030154=GO_REF:0000024, GO:0035989=GO_REF:0000024, GO:0060008=GO_REF:0000024, GO:0001894=GO_REF:0000024, GO:0035990=GO_REF:0000024, GO:0002062=GO_REF:0000024, GO:0035993=GO_REF:0000024, GO:0045944=GO_REF:0000024, GO:0030199=GO_REF:0000024, GO:0035992=GO_REF:0000024, GO:0005667=PMID:10775504, GO:0043066=GO_REF:0000024, GO:0001707=GO_REF:0000024, GO:0046982=PMID:10775504, GO:2000543=GO_REF:0000024, GO:0043425=PMID:10775504, GO:0070888=PMID:10775504, GO:0030509=GO_REF:0000024, GO:0003179=GO_REF:0000024, GO:0003677=GO_REF:0000024, GO:0006351=PMID:10775504, GO:0010628=GO_REF:0000024, GO:0043565=GO_REF:0000024, GO:0001958=GO_REF:0000024, GO:0032967=GO_REF:0000024, GO:0061036=GO_REF:0000024, GO:0061035=GO_REF:0000024, GO:0045893=GO_REF:0000024} Q7RTU7 Basic helix-loop-helix transcription factor scleraxis protein 20110826 {GO:0008284=ISS, GO:0005634=IDA, GO:0003188=ISS, GO:0030154=ISS, GO:0035989=ISS, GO:0060008=ISS, GO:0001894=ISS, GO:0035990=ISS, GO:0002062=ISS, GO:0035993=ISS, GO:0045944=ISS, GO:0030199=ISS, GO:0035992=ISS, GO:0005667=IDA, GO:0043066=ISS, GO:0001707=ISS, GO:0046982=IDA, GO:2000543=ISS, GO:0043425=IPI, GO:0070888=IDA, GO:0030509=ISS, GO:0003179=ISS, GO:0003677=ISS, GO:0006351=IDA, GO:0010628=ISS, GO:0043565=ISS, GO:0001958=ISS, GO:0032967=ISS, GO:0061036=ISS, GO:0061035=ISS, GO:0045893=ISS} BMP signaling pathway, Sertoli cell differentiation, cell differentiation, chondrocyte differentiation, collagen fibril organization, deltoid tuberosity development, endochondral ossification, heart valve formation, heart valve morphogenesis, mesoderm formation, negative regulation of apoptotic process, positive regulation of cartilage development, positive regulation of cell proliferation, positive regulation of collagen biosynthetic process, positive regulation of gastrulation, positive regulation of gene expression, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of cartilage development, tendon cell differentiation, tendon development, tendon formation, tissue homeostasis, transcription, DNA-dependent nucleus, transcription factor complex DNA binding, E-box binding, bHLH transcription factor binding, protein heterodimerization activity, sequence-specific DNA binding Human UniProtKB:Q64124 SCYL1 HPA UniProtKB {GO:0005801=PMID:18556652, GO:0030126=PMID:18556652, GO:0006355=GO_REF:0000037, GO:0005793=PMID:18556652, GO:0005794=PMID:18556652, GO:0005815=GO_REF:0000039, GO:0006890=PMID:18556652, GO:0005634=GO_REF:0000039, GO:0005524=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0004672=GO_REF:0000002, GO:0004713=PMID:10843802} Q96KG9 N-terminal kinase-like protein protein 20100326 {GO:0005801=IDA, GO:0030126=IDA, GO:0006355=IEA, GO:0005793=IDA, GO:0005794=IDA, GO:0005815=IEA, GO:0006890=IDA, GO:0005634=IEA, GO:0005524=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0005737=IDA, GO:0004672=IEA, GO:0004713=NAS} regulation of transcription, DNA-dependent, retrograde vesicle-mediated transport, Golgi to ER, transcription, DNA-dependent COPI vesicle coat, Golgi apparatus, cis-Golgi network, cytoplasm, endoplasmic reticulum-Golgi intermediate compartment, microtubule organizing center, nucleus ATP binding, DNA binding, protein kinase activity, protein tyrosine kinase activity Human SCYL2 BHF-UCL UniProtKB {GO:0005515=PMID:19643732, GO:0048471=GO_REF:0000039, GO:0005794=GO_REF:0000039, GO:2000370=PMID:19643732, GO:0030136=GO_REF:0000039, GO:0008333=PMID:19643732, GO:0005102=PMID:19643732, GO:0005524=GO_REF:0000002, GO:0004672=GO_REF:0000002, GO:0090090=PMID:19643732, GO:0010008=GO_REF:0000039, GO:0002092=PMID:19643732, GO:2000286=PMID:19643732} Q6P3W7 SCY1-like protein 2 protein 20110204 {GO:0005515=IPI, GO:0048471=IEA, GO:0005794=IEA, GO:2000370=IDA, GO:0030136=IEA, GO:0008333=IDA, GO:0005102=IPI, GO:0005524=IEA, GO:0004672=IEA, GO:0090090=IDA, GO:0010008=IEA, GO:0002092=IDA, GO:2000286=IDA} endosome to lysosome transport, negative regulation of canonical Wnt receptor signaling pathway, positive regulation of clathrin-mediated endocytosis, positive regulation of receptor internalization, receptor internalization involved in canonical Wnt receptor signaling pathway Golgi apparatus, clathrin-coated vesicle, endosome membrane, perinuclear region of cytoplasm ATP binding, protein binding, protein kinase activity, receptor binding Human UniProtKB:Q13467 SCYL3 IntAct UniProtKB {GO:0005515=PMID:12651155, GO:0005737=PMID:12651155, GO:0005794=PMID:12651155, GO:0016477=PMID:12651155, GO:0016301=PMID:12651155, GO:0006468=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0030027=PMID:12651155} Q8IZE3 Protein-associating with the carboxyl-terminal domain of ezrin protein 20130415 {GO:0005515=IPI, GO:0005737=IDA, GO:0005794=IDA, GO:0016477=NAS, GO:0016301=IDA, GO:0006468=IEA, GO:0005524=IEA, GO:0030027=IDA} cell migration, protein phosphorylation Golgi apparatus, cytoplasm, lamellipodium ATP binding, kinase activity, protein binding Human UniProtKB:P15311 SDAD1 HPA UniProtKB {GO:0003674=GO_REF:0000015, GO:0030036=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0042273=GO_REF:0000024, GO:0015031=GO_REF:0000037, GO:0000055=GO_REF:0000002} Q9NVU7 Protein SDA1 homolog protein 20110516 {GO:0003674=ND, GO:0030036=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0042273=ISS, GO:0015031=IEA, GO:0000055=IEA} actin cytoskeleton organization, protein transport, ribosomal large subunit biogenesis, ribosomal large subunit export from nucleus nucleolus, nucleus molecular_function Human SDC1 HPA UniProtKB {GO:0006629=Reactome:REACT_602, GO:0008092=GO_REF:0000002, GO:0005515=PMID:15292202, GO:0042542=GO_REF:0000019, GO:0001657=GO_REF:0000019, GO:0007603=Reactome:REACT_160125, GO:0005886=Reactome:REACT_160272, GO:0044281=Reactome:REACT_111217, GO:0051591=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0001948=GO_REF:0000019, GO:0060009=GO_REF:0000019, GO:0042476=GO_REF:0000019, GO:0055002=PMID:9566955, GO:0048627=GO_REF:0000024, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408, GO:0060070=GO_REF:0000019, GO:0043202=Reactome:REACT_121392, GO:0005796=Reactome:REACT_121320, GO:0005975=Reactome:REACT_474, GO:0006027=Reactome:REACT_120752, GO:0009636=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0008022=PMID:16982797, GO:0001523=Reactome:REACT_24968, GO:0006024=Reactome:REACT_121248, GO:0051592=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0005887=PMID:2324102, GO:0042060=GO_REF:0000019, GO:0042157=Reactome:REACT_6841, GO:0005925=GO_REF:0000052, GO:0009897=GO_REF:0000019} P18827 Syndecan-1 protein 20101115 {GO:0006629=TAS, GO:0008092=IEA, GO:0005515=IPI, GO:0042542=IEA, GO:0001657=IEA, GO:0007603=TAS, GO:0005886=TAS, GO:0044281=TAS, GO:0051591=IEA, GO:0005737=IDA, GO:0001948=IEA, GO:0060009=IEA, GO:0042476=IEA, GO:0055002=IEP, GO:0048627=ISS, GO:0030204=TAS, GO:0030203=TAS, GO:0060070=IEA, GO:0043202=TAS, GO:0005796=TAS, GO:0005975=TAS, GO:0006027=TAS, GO:0009636=IEA, GO:0051384=IEA, GO:0005576=IEA, GO:0008022=IPI, GO:0001523=TAS, GO:0006024=TAS, GO:0051592=IEA, GO:0043234=IEA, GO:0016020=IEA, GO:0005887=TAS, GO:0042060=IEA, GO:0042157=TAS, GO:0005925=IDA, GO:0009897=IEA} Sertoli cell development, canonical Wnt receptor signaling pathway, carbohydrate metabolic process, chondroitin sulfate metabolic process, glycosaminoglycan biosynthetic process, glycosaminoglycan catabolic process, glycosaminoglycan metabolic process, lipid metabolic process, lipoprotein metabolic process, myoblast development, odontogenesis, phototransduction, visible light, response to cAMP, response to calcium ion, response to glucocorticoid stimulus, response to hydrogen peroxide, response to toxic substance, retinoid metabolic process, small molecule metabolic process, striated muscle cell development, ureteric bud development, wound healing Golgi lumen, cytoplasm, external side of plasma membrane, extracellular region, focal adhesion, integral to plasma membrane, lysosomal lumen, membrane, plasma membrane, protein complex cytoskeletal protein binding, glycoprotein binding, protein C-terminus binding, protein binding Human SDC2 BHF-UCL UniProtKB {GO:0005515=PMID:11356864, GO:0008092=GO_REF:0000002, GO:0001666=GO_REF:0000019, GO:0007603=Reactome:REACT_160125, GO:0005886=Reactome:REACT_160272, GO:0005975=Reactome:REACT_474, GO:0005796=Reactome:REACT_121320, GO:0006027=Reactome:REACT_120752, GO:0044281=Reactome:REACT_111217, GO:0030165=PMID:18256285, GO:0001523=Reactome:REACT_24968, GO:0006024=Reactome:REACT_121248, GO:0048814=GO_REF:0000024, GO:0048813=GO_REF:0000019, GO:0008150=GO_REF:0000015, GO:0031000=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0005887=GO_REF:0000029, GO:0042060=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408, GO:0043202=Reactome:REACT_121392} P34741 Syndecan-2 protein 20100810 {GO:0005515=IPI, GO:0008092=IEA, GO:0001666=IEA, GO:0007603=TAS, GO:0005886=TAS, GO:0005975=TAS, GO:0005796=TAS, GO:0006027=TAS, GO:0044281=TAS, GO:0030165=IPI, GO:0001523=TAS, GO:0006024=TAS, GO:0048814=ISS, GO:0048813=IEA, GO:0008150=ND, GO:0031000=IEA, GO:0016020=IEA, GO:0005887=NAS, GO:0042060=IEA, GO:0043025=IEA, GO:0016021=IEA, GO:0030204=TAS, GO:0030203=TAS, GO:0043202=TAS} biological_process, carbohydrate metabolic process, chondroitin sulfate metabolic process, dendrite morphogenesis, glycosaminoglycan biosynthetic process, glycosaminoglycan catabolic process, glycosaminoglycan metabolic process, phototransduction, visible light, regulation of dendrite morphogenesis, response to caffeine, response to hypoxia, retinoid metabolic process, small molecule metabolic process, wound healing Golgi lumen, integral to membrane, integral to plasma membrane, lysosomal lumen, membrane, neuronal cell body, plasma membrane PDZ domain binding, cytoskeletal protein binding, protein binding Human UniProtKB:O00560 SDC3 Reactome UniProtKB {GO:0008092=GO_REF:0000002, GO:0005886=Reactome:REACT_160272, GO:0007603=Reactome:REACT_160125, GO:0005796=Reactome:REACT_121320, GO:0005975=Reactome:REACT_474, GO:0006027=Reactome:REACT_120752, GO:0044281=Reactome:REACT_111217, GO:0001523=Reactome:REACT_24968, GO:0006024=Reactome:REACT_121248, GO:0016021=GO_REF:0000037, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408, GO:0043202=Reactome:REACT_121392} O75056 Syndecan-3 protein 20130301 {GO:0008092=IEA, GO:0005886=TAS, GO:0007603=TAS, GO:0005796=TAS, GO:0005975=TAS, GO:0006027=TAS, GO:0044281=TAS, GO:0001523=TAS, GO:0006024=TAS, GO:0016021=IEA, GO:0030204=TAS, GO:0030203=TAS, GO:0043202=TAS} carbohydrate metabolic process, chondroitin sulfate metabolic process, glycosaminoglycan biosynthetic process, glycosaminoglycan catabolic process, glycosaminoglycan metabolic process, phototransduction, visible light, retinoid metabolic process, small molecule metabolic process Golgi lumen, integral to membrane, lysosomal lumen, plasma membrane cytoskeletal protein binding Human SDC4 BHF-UCL UniProtKB {GO:0005515=PMID:12571249, GO:0008092=GO_REF:0000002, GO:0001657=GO_REF:0000019, GO:0005886=Reactome:REACT_160272, GO:0007603=Reactome:REACT_160125, GO:0044281=Reactome:REACT_111217, GO:0051894=GO_REF:0000019, GO:0005080=GO_REF:0000019, GO:0045860=GO_REF:0000019, GO:0001968=GO_REF:0000019, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408, GO:0043202=Reactome:REACT_121392, GO:0009986=GO_REF:0000019, GO:0005796=Reactome:REACT_121320, GO:0005975=Reactome:REACT_474, GO:0006027=Reactome:REACT_120752, GO:0005576=GO_REF:0000039, GO:0001523=Reactome:REACT_24968, GO:0006024=Reactome:REACT_121248, GO:0008150=GO_REF:0000015, GO:0005887=PMID:1500433, GO:0051496=GO_REF:0000019, GO:0043034=GO_REF:0000019, GO:0045121=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0005925=GO_REF:0000019, GO:0070053=PMID:17879962} P31431 Syndecan-4 protein 20081021 {GO:0005515=IPI, GO:0008092=IEA, GO:0001657=IEA, GO:0005886=TAS, GO:0007603=TAS, GO:0044281=TAS, GO:0051894=IEA, GO:0005080=IEA, GO:0045860=IEA, GO:0001968=IEA, GO:0030204=TAS, GO:0030203=TAS, GO:0043202=TAS, GO:0009986=IEA, GO:0005796=TAS, GO:0005975=TAS, GO:0006027=TAS, GO:0005576=IEA, GO:0001523=TAS, GO:0006024=TAS, GO:0008150=ND, GO:0005887=NAS, GO:0051496=IEA, GO:0043034=IEA, GO:0045121=IEA, GO:0016021=IEA, GO:0005925=IEA, GO:0070053=IMP} biological_process, carbohydrate metabolic process, chondroitin sulfate metabolic process, glycosaminoglycan biosynthetic process, glycosaminoglycan catabolic process, glycosaminoglycan metabolic process, phototransduction, visible light, positive regulation of focal adhesion assembly, positive regulation of protein kinase activity, positive regulation of stress fiber assembly, retinoid metabolic process, small molecule metabolic process, ureteric bud development Golgi lumen, cell surface, costamere, extracellular region, focal adhesion, integral to membrane, integral to plasma membrane, lysosomal lumen, membrane raft, plasma membrane cytoskeletal protein binding, fibronectin binding, protein binding, protein kinase C binding, thrombospondin receptor activity Human SDCBP BHF-UCL UniProtKB {GO:0005137=PMID:11498591, GO:0030036=PMID:12037664, GO:0005886=PMID:18256285, GO:0046330=PMID:18256285, GO:0007268=PMID:9883737, GO:0007265=GO_REF:0000019, GO:0005634=PMID:11179419, GO:0042803=GO_REF:0000019, GO:0005829=Reactome:REACT_22139, GO:0005109=PMID:18256285, GO:0035556=PMID:9391086, GO:0006930=PMID:12037664, GO:0005737=PMID:18256285, GO:0001948=GO_REF:0000019, GO:0019838=GO_REF:0000019, GO:0005912=PMID:11179419, GO:0007411=Reactome:REACT_18266, GO:0006612=PMID:10230395, GO:0005856=PMID:9391086, GO:0050839=GO_REF:0000019, GO:0008093=PMID:9391086, GO:0042470=GO_REF:0000039, GO:0046982=PMID:11152476, GO:0005895=PMID:11498591, GO:0008022=GO_REF:0000019, GO:0042043=GO_REF:0000019, GO:0047485=PMID:15371445, GO:0046875=GO_REF:0000019, GO:0016020=PMID:9391086, GO:0005789=GO_REF:0000039, GO:0005925=GO_REF:0000039, GO:0045545=PMID:18256285, GO:0042327=PMID:18256285} O00560 Syntenin-1 protein 20100810 {GO:0005137=ISS, GO:0030036=NAS, GO:0005886=IDA, GO:0046330=IC, GO:0007268=NAS, GO:0007265=IEA, GO:0005634=NAS, GO:0042803=IEA, GO:0005829=TAS, GO:0005109=IPI, GO:0035556=NAS, GO:0006930=NAS, GO:0005737=IDA, GO:0001948=IEA, GO:0019838=IEA, GO:0005912=NAS, GO:0007411=TAS, GO:0006612=NAS, GO:0005856=NAS, GO:0050839=IEA, GO:0008093=NAS, GO:0042470=IEA, GO:0046982=IPI, GO:0005895=ISS, GO:0008022=IEA, GO:0042043=IEA, GO:0047485=IPI, GO:0046875=IEA, GO:0016020=NAS, GO:0005789=IEA, GO:0005925=IEA, GO:0045545=IPI, GO:0042327=IDA} Ras protein signal transduction, actin cytoskeleton organization, axon guidance, intracellular signal transduction, positive regulation of JNK cascade, positive regulation of phosphorylation, protein targeting to membrane, substrate-dependent cell migration, cell extension, synaptic transmission adherens junction, cytoplasm, cytoskeleton, cytosol, endoplasmic reticulum membrane, focal adhesion, interleukin-5 receptor complex, melanosome, membrane, nucleus, plasma membrane cell adhesion molecule binding, cytoskeletal adaptor activity, ephrin receptor binding, frizzled binding, glycoprotein binding, growth factor binding, interleukin-5 receptor binding, neurexin family protein binding, protein C-terminus binding, protein N-terminus binding, protein heterodimerization activity, protein homodimerization activity, syndecan binding Human GO:0042327 SDCBP2 UniProtKB UniProtKB {GO:0035556=PMID:11152476, GO:0005737=PMID:11152476, GO:0046982=PMID:11152476, GO:0005886=PMID:11152476, GO:0046907=PMID:11152476, GO:0008022=PMID:11152476, GO:0042803=PMID:11152476, GO:0007399=PMID:11152476} Q9H190 Syntenin-2 protein 20040202 {GO:0035556=NAS, GO:0005737=IDA, GO:0046982=IPI, GO:0005886=IC, GO:0046907=NAS, GO:0008022=IPI, GO:0042803=IDA, GO:0007399=NAS} intracellular signal transduction, intracellular transport, nervous system development cytoplasm, plasma membrane protein C-terminus binding, protein heterodimerization activity, protein homodimerization activity Human SDCCAG3 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q96C92 Serologically defined colon cancer antigen 3 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 SDCCAG8 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0005813=PMID:21399614, GO:0005911=PMID:20835237, GO:0005814=PMID:20835237, GO:0000086=Reactome:REACT_2203, GO:0035148=GO_REF:0000024, GO:0030010=GO_REF:0000024, GO:0000278=Reactome:REACT_152, GO:0005829=Reactome:REACT_15470} Q86SQ7 Serologically defined colon cancer antigen 8 protein 20130415 {GO:0005515=IPI, GO:0005813=IDA, GO:0005911=IDA, GO:0005814=IDA, GO:0000086=TAS, GO:0035148=ISS, GO:0030010=ISS, GO:0000278=TAS, GO:0005829=TAS} G2/M transition of mitotic cell cycle, establishment of cell polarity, mitotic cell cycle, tube formation cell-cell junction, centriole, centrosome, cytosol protein binding Human UniProtKB:P04591:PRO_0000038593 SDF2 PINC UniProtKB {GO:0004169=PMID:8918255, GO:0016020=GO_REF:0000002, GO:0006486=PMID:8918255, GO:0005615=PMID:8918255} Q99470 Stromal cell-derived factor 2 protein 20030904 {GO:0004169=TAS, GO:0016020=IEA, GO:0006486=TAS, GO:0005615=TAS} protein glycosylation extracellular space, membrane dolichyl-phosphate-mannose-protein mannosyltransferase activity Human SDF2L1 UniProtKB UniProtKB {GO:0016020=GO_REF:0000002, GO:0005788=GO_REF:0000039} Q9HCN8 Stromal cell-derived factor 2-like protein 1 protein 20130413 {GO:0016020=IEA, GO:0005788=IEA} endoplasmic reticulum lumen, membrane Human UniProtKB-SubCell:SL-0096 SDF4 BHF-UCL UniProtKB {GO:0009650=PMID:18355758, GO:0005886=PMID:17442889, GO:0005770=GO_REF:0000024, GO:0005796=GO_REF:0000024, GO:0045471=PMID:18355758, GO:0070625=PMID:17442889, GO:0005509=GO_REF:0000024, GO:0021549=PMID:18355758, GO:0042802=PMID:17442889, GO:0005737=PMID:17442889, GO:0032059=GO_REF:0000039, GO:0017156=PMID:17442889, GO:0045444=GO_REF:0000024} Q9BRK5 45 kDa calcium-binding protein protein 20090617 {GO:0009650=ISS, GO:0005886=ISS, GO:0005770=ISS, GO:0005796=ISS, GO:0045471=ISS, GO:0070625=ISS, GO:0005509=ISS, GO:0021549=ISS, GO:0042802=ISS, GO:0005737=ISS, GO:0032059=IEA, GO:0017156=ISS, GO:0045444=ISS} UV protection, calcium ion-dependent exocytosis, cerebellum development, fat cell differentiation, response to ethanol, zymogen granule exocytosis Golgi lumen, bleb, cytoplasm, late endosome, plasma membrane calcium ion binding, identical protein binding Human UniProtKB:Q91ZS3-2 SDHA IntAct UniProtKB {GO:0005515=PMID:19688755, GO:0006099=Reactome:REACT_1785, GO:0050660=GO_REF:0000002, GO:0005743=Reactome:REACT_1667, GO:0044281=Reactome:REACT_111217, GO:0008177=GO_REF:0000003, GO:0016627=GO_REF:0000002, GO:0007399=PMID:16361598, GO:0005739=PMID:7550341, GO:0022904=Reactome:REACT_22393, GO:0005749=GO_REF:0000024, GO:0006105=PMID:7550341, GO:0000104=PMID:7550341, GO:0022900=GO_REF:0000002, GO:0055114=PMID:7550341} P31040 "Succinate dehydrogenase ""ubiquinone"" flavoprotein subunit, mitochondrial" protein 20130415 {GO:0005515=IPI, GO:0006099=TAS, GO:0050660=IEA, GO:0005743=TAS, GO:0044281=TAS, GO:0008177=IEA, GO:0016627=IEA, GO:0007399=IMP, GO:0005739=IDA, GO:0022904=TAS, GO:0005749=ISS, GO:0006105=IDA, GO:0000104=IMP, GO:0022900=IEA, GO:0055114=IDA} electron transport chain, nervous system development, oxidation-reduction process, respiratory electron transport chain, small molecule metabolic process, succinate metabolic process, tricarboxylic acid cycle mitochondrial inner membrane, mitochondrial respiratory chain complex II, mitochondrion flavin adenine dinucleotide binding, oxidoreductase activity, acting on the CH-CH group of donors, protein binding, succinate dehydrogenase (ubiquinone) activity, succinate dehydrogenase activity Human UniProtKB:P21912 SDHAF2 HPA UniProtKB {GO:0005515=PMID:19628817, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0006121=PMID:19628817, GO:0005730=GO_REF:0000052, GO:0018293=PMID:19628817} Q9NX18 Succinate dehydrogenase assembly factor 2, mitochondrial protein 20110516 {GO:0005515=IPI, GO:0005739=IDA, GO:0005737=IDA, GO:0006121=IMP, GO:0005730=IDA, GO:0018293=IMP} mitochondrial electron transport, succinate to ubiquinone, protein-FAD linkage cytoplasm, mitochondrion, nucleolus protein binding Human SDHB HPA UniProtKB {GO:0005515=PMID:19688755, GO:0048039=GO_REF:0000024, GO:0051538=GO_REF:0000024, GO:0006099=Reactome:REACT_1785, GO:0051539=GO_REF:0000024, GO:0051537=GO_REF:0000024, GO:0005743=Reactome:REACT_1667, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0008177=GO_REF:0000003, GO:0046872=GO_REF:0000037, GO:0022904=Reactome:REACT_22393, GO:0009060=PMID:2302193, GO:0005739=GO_REF:0000052, GO:0006105=GO_REF:0000019, GO:0005749=GO_REF:0000024} P21912 "Succinate dehydrogenase ""ubiquinone"" iron-sulfur subunit, mitochondrial" protein 20080205 {GO:0005515=IPI, GO:0048039=ISS, GO:0051538=ISS, GO:0006099=TAS, GO:0051539=ISS, GO:0051537=ISS, GO:0005743=TAS, GO:0009055=IEA, GO:0044281=TAS, GO:0008177=IEA, GO:0046872=IEA, GO:0022904=TAS, GO:0009060=TAS, GO:0005739=IDA, GO:0006105=IEA, GO:0005749=ISS} aerobic respiration, respiratory electron transport chain, small molecule metabolic process, succinate metabolic process, tricarboxylic acid cycle mitochondrial inner membrane, mitochondrial respiratory chain complex II, mitochondrion 2 iron, 2 sulfur cluster binding, 3 iron, 4 sulfur cluster binding, 4 iron, 4 sulfur cluster binding, electron carrier activity, metal ion binding, protein binding, succinate dehydrogenase (ubiquinone) activity, ubiquinone binding Human SDHC Reactome UniProtKB {GO:0006099=Reactome:REACT_1785, GO:0005743=Reactome:REACT_1667, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0009060=PMID:9533030, GO:0005739=PMID:2302193, GO:0022904=Reactome:REACT_22393, GO:0005749=GO_REF:0000024, GO:0000104=GO_REF:0000002, GO:0016021=PMID:9533030, GO:0045273=PMID:9533030, GO:0020037=GO_REF:0000024, GO:0055114=PMID:9533030} Q99643 Succinate dehydrogenase cytochrome b560 subunit, mitochondrial protein 20070618 {GO:0006099=TAS, GO:0005743=TAS, GO:0009055=IEA, GO:0044281=TAS, GO:0046872=IEA, GO:0009060=TAS, GO:0005739=TAS, GO:0022904=TAS, GO:0005749=ISS, GO:0000104=IEA, GO:0016021=TAS, GO:0045273=TAS, GO:0020037=ISS, GO:0055114=TAS} aerobic respiration, oxidation-reduction process, respiratory electron transport chain, small molecule metabolic process, tricarboxylic acid cycle integral to membrane, mitochondrial inner membrane, mitochondrial respiratory chain complex II, mitochondrion, respiratory chain complex II electron carrier activity, heme binding, metal ion binding, succinate dehydrogenase activity Human SDHD Reactome UniProtKB {GO:0048039=GO_REF:0000024, GO:0006099=Reactome:REACT_1785, GO:0005743=Reactome:REACT_1667, GO:0009055=PMID:9533030, GO:0005740=PMID:9533030, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0005739=PMID:2302193, GO:0022904=Reactome:REACT_22393, GO:0005749=GO_REF:0000024, GO:0000104=PMID:9533030, GO:0016021=GO_REF:0000037, GO:0020037=GO_REF:0000024} O14521 "Succinate dehydrogenase ""ubiquinone"" cytochrome b small subunit, mitochondrial" protein 20120320 {GO:0048039=ISS, GO:0006099=TAS, GO:0005743=TAS, GO:0009055=TAS, GO:0005740=TAS, GO:0044281=TAS, GO:0046872=IEA, GO:0005739=TAS, GO:0022904=TAS, GO:0005749=ISS, GO:0000104=IDA, GO:0016021=IEA, GO:0020037=ISS} respiratory electron transport chain, small molecule metabolic process, tricarboxylic acid cycle integral to membrane, mitochondrial envelope, mitochondrial inner membrane, mitochondrial respiratory chain complex II, mitochondrion electron carrier activity, heme binding, metal ion binding, succinate dehydrogenase activity, ubiquinone binding Human SDK1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037} Q7Z5N4 Protein sidekick-1 protein 20130413 {GO:0016021=IEA, GO:0007155=IEA} cell adhesion integral to membrane Human UniProtKB-KW:KW-0812 SDK2 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037} Q58EX2 Protein sidekick-2 protein 20130413 {GO:0016021=IEA, GO:0007155=IEA} cell adhesion integral to membrane Human UniProtKB-KW:KW-0812 SDPR HPA UniProtKB {GO:0005515=PMID:19722192, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0005543=PMID:10191091, GO:0005886=GO_REF:0000052, GO:0005901=GO_REF:0000039, GO:0001786=PMID:2390065, GO:0005829=PMID:2390065} O95810 Serum deprivation-response protein protein 20110516 {GO:0005515=IPI, GO:0005737=IDA, GO:0005794=IDA, GO:0005543=TAS, GO:0005886=IDA, GO:0005901=IEA, GO:0001786=IDA, GO:0005829=IDA} Golgi apparatus, caveola, cytoplasm, cytosol, plasma membrane phosphatidylserine binding, phospholipid binding, protein binding Human SDR16C5 UniProtKB UniProtKB {GO:0050908=PMID:12407145, GO:0042574=PMID:18926804, GO:0042572=PMID:18926804, GO:0005789=PMID:18926804, GO:0016491=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0004745=PMID:18926804, GO:0043616=PMID:12372410} Q8N3Y7 Epidermal retinol dehydrogenase 2 protein 20100129 {GO:0050908=NAS, GO:0042574=IDA, GO:0042572=IDA, GO:0005789=IDA, GO:0016491=IEA, GO:0016021=IEA, GO:0004745=IDA, GO:0043616=IMP} detection of light stimulus involved in visual perception, keratinocyte proliferation, retinal metabolic process, retinol metabolic process endoplasmic reticulum membrane, integral to membrane oxidoreductase activity, retinol dehydrogenase activity Human SDR39U1 UniProtKB UniProtKB {GO:0016491=GO_REF:0000037} Q9NRG7 Epimerase family protein SDR39U1 protein 20130413 {GO:0016491=IEA} oxidoreductase activity Human UniProtKB-KW:KW-0560 SDR42E1 UniProtKB UniProtKB {GO:0006694=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0003854=GO_REF:0000002} Q8WUS8 Short-chain dehydrogenase/reductase family 42E member 1 protein 20130413 {GO:0006694=IEA, GO:0016021=IEA, GO:0003854=IEA} steroid biosynthetic process integral to membrane 3-beta-hydroxy-delta5-steroid dehydrogenase activity Human UniProtKB-KW:KW-0812 SDSL UniProtKB UniProtKB {GO:0003941=GO_REF:0000003, GO:0005739=GO_REF:0000019, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0006520=GO_REF:0000002, GO:0030170=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0004794=GO_REF:0000003} Q96GA7 Serine dehydratase-like protein 20090707 {GO:0003941=IEA, GO:0005739=IEA, GO:0003674=ND, GO:0008150=ND, GO:0006520=IEA, GO:0030170=IEA, GO:0005575=ND, GO:0004794=IEA} biological_process, cellular amino acid metabolic process cellular_component, mitochondrion L-serine ammonia-lyase activity, L-threonine ammonia-lyase activity, molecular_function, pyridoxal phosphate binding Human SEC11A Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0050796=Reactome:REACT_23974, GO:0006614=Reactome:REACT_115902, GO:0005789=Reactome:REACT_19296, GO:0006508=GO_REF:0000037, GO:0008236=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0006465=GO_REF:0000002} P67812 Signal peptidase complex catalytic subunit SEC11A protein 20130213 {GO:0010467=TAS, GO:0050796=TAS, GO:0006614=TAS, GO:0005789=TAS, GO:0006508=IEA, GO:0008236=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0006412=TAS, GO:0006465=IEA} SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, proteolysis, regulation of insulin secretion, signal peptide processing, translation endoplasmic reticulum membrane, integral to membrane serine-type peptidase activity Human SEC11B UniProtKB UniProtKB {GO:0006508=GO_REF:0000037, GO:0008236=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0006465=GO_REF:0000002} P0C7V7 Putative signal peptidase complex catalytic subunit SEC11B protein 20130413 {GO:0006508=IEA, GO:0008236=IEA, GO:0016021=IEA, GO:0006465=IEA} proteolysis, signal peptide processing integral to membrane serine-type peptidase activity Human UniProtKB-KW:KW-0812 SEC11C Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0050796=Reactome:REACT_23974, GO:0006614=Reactome:REACT_115902, GO:0005789=Reactome:REACT_19296, GO:0006508=GO_REF:0000037, GO:0008236=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0006465=GO_REF:0000002} Q9BY50 Signal peptidase complex catalytic subunit SEC11C protein 20130213 {GO:0010467=TAS, GO:0050796=TAS, GO:0006614=TAS, GO:0005789=TAS, GO:0006508=IEA, GO:0008236=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0006412=TAS, GO:0006465=IEA} SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, proteolysis, regulation of insulin secretion, signal peptide processing, translation endoplasmic reticulum membrane, integral to membrane serine-type peptidase activity Human SEC13 IntAct UniProtKB {GO:0005515=PMID:18160040, GO:0012507=Reactome:REACT_75799, GO:0000236=Reactome:REACT_682, GO:0002474=Reactome:REACT_75820, GO:0048208=Reactome:REACT_12507, GO:0005635=PMID:15146057, GO:0006886=PMID:7987303, GO:0005829=Reactome:REACT_150414, GO:0006888=Reactome:REACT_11203, GO:0019886=Reactome:REACT_121399, GO:0031080=PMID:15146057, GO:0000087=Reactome:REACT_910, GO:0005789=Reactome:REACT_121121, GO:0000776=PMID:15146057, GO:0051028=GO_REF:0000037, GO:0000278=Reactome:REACT_152, GO:0044267=Reactome:REACT_17015, GO:0000090=Reactome:REACT_1275, GO:0016044=Reactome:REACT_11123, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} P55735 Protein SEC13 homolog protein 20130415 {GO:0005515=IPI, GO:0012507=TAS, GO:0000236=TAS, GO:0002474=TAS, GO:0048208=TAS, GO:0005635=IDA, GO:0006886=NAS, GO:0005829=TAS, GO:0006888=TAS, GO:0019886=TAS, GO:0031080=NAS, GO:0000087=TAS, GO:0005789=TAS, GO:0000776=IDA, GO:0051028=IEA, GO:0000278=TAS, GO:0044267=TAS, GO:0000090=TAS, GO:0016044=TAS, GO:0043687=TAS, GO:0018279=TAS} COPII vesicle coating, ER to Golgi vesicle-mediated transport, M phase of mitotic cell cycle, antigen processing and presentation of exogenous peptide antigen via MHC class II, antigen processing and presentation of peptide antigen via MHC class I, cellular membrane organization, cellular protein metabolic process, intracellular protein transport, mRNA transport, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, post-translational protein modification, protein N-linked glycosylation via asparagine ER to Golgi transport vesicle membrane, cytosol, endoplasmic reticulum membrane, kinetochore, nuclear envelope, nuclear pore outer ring protein binding Human UniProtKB:P49687 SEC14L1 PINC UniProtKB {GO:0005794=PMID:8697811, GO:0016020=PMID:8697811, GO:0006810=GO_REF:0000002, GO:0016021=GO_REF:0000002} Q92503 SEC14-like protein 1 protein 20030904 {GO:0005794=TAS, GO:0016020=TAS, GO:0006810=IEA, GO:0016021=IEA} transport Golgi apparatus, integral to membrane, membrane Human SEC14L2 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0005215=GO_REF:0000002, GO:0005737=PMID:10829015, GO:0005543=PMID:7364757, GO:0045540=PMID:11226224, GO:0006810=GO_REF:0000002, GO:0005634=PMID:11444841, GO:0016021=GO_REF:0000002, GO:0045893=PMID:11444841, GO:0008431=PMID:10829015, GO:0006351=GO_REF:0000037} O76054 SEC14-like protein 2 protein 20020829 {GO:0005622=IEA, GO:0005215=IEA, GO:0005737=NAS, GO:0005543=NAS, GO:0045540=NAS, GO:0006810=IEA, GO:0005634=NAS, GO:0016021=IEA, GO:0045893=NAS, GO:0008431=NAS, GO:0006351=IEA} positive regulation of transcription, DNA-dependent, regulation of cholesterol biosynthetic process, transcription, DNA-dependent, transport cytoplasm, integral to membrane, intracellular, nucleus phospholipid binding, transporter activity, vitamin E binding Human SEC14L3 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0005215=GO_REF:0000002, GO:0006810=GO_REF:0000002, GO:0016021=GO_REF:0000002, GO:0008289=GO_REF:0000037} Q9UDX4 SEC14-like protein 3 protein 20130413 {GO:0005622=IEA, GO:0005215=IEA, GO:0006810=IEA, GO:0016021=IEA, GO:0008289=IEA} transport integral to membrane, intracellular lipid binding, transporter activity Human UniProtKB-KW:KW-0446 SEC14L4 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0005215=GO_REF:0000002, GO:0006810=GO_REF:0000002, GO:0016021=GO_REF:0000002, GO:0008289=GO_REF:0000037} Q9UDX3 SEC14-like protein 4 protein 20130413 {GO:0005622=IEA, GO:0005215=IEA, GO:0006810=IEA, GO:0016021=IEA, GO:0008289=IEA} transport integral to membrane, intracellular lipid binding, transporter activity Human UniProtKB-KW:KW-0446 SEC16A InterPro UniProtKB {GO:0000139=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0048208=GO_REF:0000002, GO:0015031=GO_REF:0000037, GO:0007029=PMID:21768384, GO:0005829=PMID:21768384} Q8N9G1 cDNA FLJ37437 fis, clone BRAWH2003025 protein 20130413 {GO:0000139=IEA, GO:0005789=IEA, GO:0048208=IEA, GO:0015031=IEA, GO:0007029=IDA, GO:0005829=IDA} COPII vesicle coating, endoplasmic reticulum organization, protein transport Golgi membrane, cytosol, endoplasmic reticulum membrane Human InterPro:IPR024880 SEC16B UniProtKB UniProtKB {GO:0000139=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0007031=PMID:21768384, GO:0048208=GO_REF:0000002, GO:0015031=GO_REF:0000037, GO:0007029=PMID:21768384, GO:0016559=PMID:21768384, GO:0043231=PMID:21768384} Q96JE7 Protein transport protein Sec16B protein 20121015 {GO:0000139=IEA, GO:0005789=IEA, GO:0007031=IDA, GO:0048208=IEA, GO:0015031=IEA, GO:0007029=IDA, GO:0016559=IMP, GO:0043231=IDA} COPII vesicle coating, endoplasmic reticulum organization, peroxisome fission, peroxisome organization, protein transport Golgi membrane, endoplasmic reticulum membrane, intracellular membrane-bounded organelle Human SEC22A PINC UniProtKB {GO:0006888=GO_REF:0000019, GO:0005215=PMID:8621431, GO:0005789=GO_REF:0000039, GO:0006810=GO_REF:0000002, GO:0016021=GO_REF:0000019, GO:0015031=GO_REF:0000037} Q96IW7 Vesicle-trafficking protein SEC22a protein 20061107 {GO:0006888=IEA, GO:0005215=TAS, GO:0005789=IEA, GO:0006810=IEA, GO:0016021=IEA, GO:0015031=IEA} ER to Golgi vesicle-mediated transport, protein transport, transport endoplasmic reticulum membrane, integral to membrane transporter activity Human SEC22B HGNC UniProtKB {GO:0006888=PMID:9094723, GO:0005515=PMID:15272311, GO:0042470=GO_REF:0000039, GO:0005793=PMID:15308636, GO:0000139=GO_REF:0000039, GO:0033116=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0015031=GO_REF:0000037} O75396 Vesicle-trafficking protein SEC22b protein 20060522 {GO:0006888=TAS, GO:0005515=IPI, GO:0042470=IEA, GO:0005793=IDA, GO:0000139=IEA, GO:0033116=IEA, GO:0005789=IEA, GO:0016021=IEA, GO:0015031=IEA} ER to Golgi vesicle-mediated transport, protein transport Golgi membrane, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment, endoplasmic reticulum-Golgi intermediate compartment membrane, integral to membrane, melanosome protein binding Human UniProtKB:Q12981 SEC22C PINC UniProtKB {GO:0006888=PMID:9501016, GO:0016020=GO_REF:0000038, GO:0005783=PMID:9501016, GO:0005789=GO_REF:0000039, GO:0006810=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0015031=GO_REF:0000037} Q9BRL7 Vesicle-trafficking protein SEC22c protein 20030904 {GO:0006888=TAS, GO:0016020=IEA, GO:0005783=TAS, GO:0005789=IEA, GO:0006810=IEA, GO:0016021=IEA, GO:0015031=IEA} ER to Golgi vesicle-mediated transport, protein transport, transport endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, membrane Human SEC23A IntAct UniProtKB {GO:0005515=PMID:18692470, GO:0002474=Reactome:REACT_75820, GO:0012507=Reactome:REACT_75799, GO:0048471=GO_REF:0000019, GO:0030127=GO_REF:0000002, GO:0005783=PMID:8898360, GO:0048208=Reactome:REACT_12507, GO:0044281=Reactome:REACT_111217, GO:0006886=GO_REF:0000002, GO:0005829=Reactome:REACT_75799, GO:0006888=Reactome:REACT_11203, GO:0019886=Reactome:REACT_121399, GO:0000139=GO_REF:0000039, GO:0030868=GO_REF:0000039, GO:0005789=Reactome:REACT_121121, GO:0008270=GO_REF:0000002, GO:0016192=PMID:8898360, GO:0044267=Reactome:REACT_17015, GO:0016044=Reactome:REACT_11123, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q15436 Protein transport protein Sec23A protein 20130415 {GO:0005515=IPI, GO:0002474=TAS, GO:0012507=TAS, GO:0048471=IEA, GO:0030127=IEA, GO:0005783=TAS, GO:0048208=TAS, GO:0044281=TAS, GO:0006886=IEA, GO:0005829=TAS, GO:0006888=TAS, GO:0019886=TAS, GO:0000139=IEA, GO:0030868=IEA, GO:0005789=TAS, GO:0008270=IEA, GO:0016192=TAS, GO:0044267=TAS, GO:0016044=TAS, GO:0043687=TAS, GO:0018279=TAS} COPII vesicle coating, ER to Golgi vesicle-mediated transport, antigen processing and presentation of exogenous peptide antigen via MHC class II, antigen processing and presentation of peptide antigen via MHC class I, cellular membrane organization, cellular protein metabolic process, intracellular protein transport, post-translational protein modification, protein N-linked glycosylation via asparagine, small molecule metabolic process, vesicle-mediated transport COPII vesicle coat, ER to Golgi transport vesicle membrane, Golgi membrane, cytosol, endoplasmic reticulum, endoplasmic reticulum membrane, perinuclear region of cytoplasm, smooth endoplasmic reticulum membrane protein binding, zinc ion binding Human UniProtKB:P53992 SEC23B HPA UniProtKB {GO:0006888=GO_REF:0000002, GO:0048471=GO_REF:0000019, GO:0030127=GO_REF:0000002, GO:0016020=PMID:8898360, GO:0000139=GO_REF:0000039, GO:0033116=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0016192=PMID:8898360, GO:0006886=GO_REF:0000002, GO:0043231=GO_REF:0000052} Q5QPE2 Protein transport protein Sec23B protein 20080818 {GO:0006888=IEA, GO:0048471=IEA, GO:0030127=IEA, GO:0016020=TAS, GO:0000139=IEA, GO:0033116=IEA, GO:0005789=IEA, GO:0008270=IEA, GO:0016192=TAS, GO:0006886=IEA, GO:0043231=IDA} ER to Golgi vesicle-mediated transport, intracellular protein transport, vesicle-mediated transport COPII vesicle coat, Golgi membrane, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment membrane, intracellular membrane-bounded organelle, membrane, perinuclear region of cytoplasm zinc ion binding Human SEC23IP HPA UniProtKB {GO:0012507=GO_REF:0000039, GO:0005793=PMID:10400679, GO:0005737=PMID:10400679, GO:0005783=GO_REF:0000039, GO:0007030=PMID:10400679, GO:0006886=PMID:10400679, GO:0046872=GO_REF:0000002, GO:0043231=GO_REF:0000052} Q9Y6Y8 SEC23-interacting protein protein 20110516 {GO:0012507=IEA, GO:0005793=TAS, GO:0005737=TAS, GO:0005783=IEA, GO:0007030=TAS, GO:0006886=TAS, GO:0046872=IEA, GO:0043231=IDA} Golgi organization, intracellular protein transport ER to Golgi transport vesicle membrane, cytoplasm, endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment, intracellular membrane-bounded organelle metal ion binding Human SEC24A Reactome UniProtKB {GO:0002474=Reactome:REACT_75820, GO:0012507=Reactome:REACT_75799, GO:0048471=GO_REF:0000039, GO:0030127=GO_REF:0000029, GO:0048208=Reactome:REACT_12507, GO:0044281=Reactome:REACT_111217, GO:0006886=GO_REF:0000002, GO:0005829=Reactome:REACT_75799, GO:0006888=Reactome:REACT_11203, GO:0019886=Reactome:REACT_121399, GO:0003674=GO_REF:0000015, GO:0000139=GO_REF:0000039, GO:0005789=Reactome:REACT_121121, GO:0008270=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0016044=Reactome:REACT_11123, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} O95486 Protein transport protein Sec24A protein 20130301 {GO:0002474=TAS, GO:0012507=TAS, GO:0048471=IEA, GO:0030127=NAS, GO:0048208=TAS, GO:0044281=TAS, GO:0006886=IEA, GO:0005829=TAS, GO:0006888=TAS, GO:0019886=TAS, GO:0003674=ND, GO:0000139=IEA, GO:0005789=TAS, GO:0008270=IEA, GO:0044267=TAS, GO:0016044=TAS, GO:0043687=TAS, GO:0018279=TAS} COPII vesicle coating, ER to Golgi vesicle-mediated transport, antigen processing and presentation of exogenous peptide antigen via MHC class II, antigen processing and presentation of peptide antigen via MHC class I, cellular membrane organization, cellular protein metabolic process, intracellular protein transport, post-translational protein modification, protein N-linked glycosylation via asparagine, small molecule metabolic process COPII vesicle coat, ER to Golgi transport vesicle membrane, Golgi membrane, cytosol, endoplasmic reticulum membrane, perinuclear region of cytoplasm molecular_function, zinc ion binding Human SEC24B Reactome UniProtKB {GO:0005515=PMID:19706601, GO:0012507=Reactome:REACT_75799, GO:0005215=PMID:10075675, GO:0002474=Reactome:REACT_75820, GO:0048471=GO_REF:0000039, GO:0030127=GO_REF:0000002, GO:0048208=Reactome:REACT_12507, GO:0044281=Reactome:REACT_111217, GO:0006886=GO_REF:0000002, GO:0005829=Reactome:REACT_75799, GO:0006888=Reactome:REACT_11203, GO:0019886=Reactome:REACT_121399, GO:0000139=GO_REF:0000039, GO:0016020=PMID:10075675, GO:0005789=Reactome:REACT_121121, GO:0008270=GO_REF:0000002, GO:0016192=PMID:10075675, GO:0044267=Reactome:REACT_17015, GO:0016044=Reactome:REACT_11123, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} O95487 Protein transport protein Sec24B protein 20130301 {GO:0005515=IPI, GO:0012507=TAS, GO:0005215=TAS, GO:0002474=TAS, GO:0048471=IEA, GO:0030127=IEA, GO:0048208=TAS, GO:0044281=TAS, GO:0006886=IEA, GO:0005829=TAS, GO:0006888=TAS, GO:0019886=TAS, GO:0000139=IEA, GO:0016020=TAS, GO:0005789=TAS, GO:0008270=IEA, GO:0016192=TAS, GO:0044267=TAS, GO:0016044=TAS, GO:0043687=TAS, GO:0018279=TAS} COPII vesicle coating, ER to Golgi vesicle-mediated transport, antigen processing and presentation of exogenous peptide antigen via MHC class II, antigen processing and presentation of peptide antigen via MHC class I, cellular membrane organization, cellular protein metabolic process, intracellular protein transport, post-translational protein modification, protein N-linked glycosylation via asparagine, small molecule metabolic process, vesicle-mediated transport COPII vesicle coat, ER to Golgi transport vesicle membrane, Golgi membrane, cytosol, endoplasmic reticulum membrane, membrane, perinuclear region of cytoplasm protein binding, transporter activity, zinc ion binding Human SEC24C HPA UniProtKB {GO:0005515=PMID:18692470, GO:0012507=Reactome:REACT_75799, GO:0002474=Reactome:REACT_75820, GO:0048471=GO_REF:0000039, GO:0030127=PMID:10214955, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0048208=Reactome:REACT_12507, GO:0044281=Reactome:REACT_111217, GO:0006886=GO_REF:0000002, GO:0005829=Reactome:REACT_75799, GO:0043231=GO_REF:0000052, GO:0006888=Reactome:REACT_11203, GO:0019886=Reactome:REACT_121399, GO:0003674=GO_REF:0000015, GO:0000139=GO_REF:0000039, GO:0005789=Reactome:REACT_147893, GO:0008270=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0016044=Reactome:REACT_11123, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} P53992 Protein transport protein Sec24C protein 20111111 {GO:0005515=IPI, GO:0012507=TAS, GO:0002474=TAS, GO:0048471=IEA, GO:0030127=NAS, GO:0005730=IDA, GO:0005634=IDA, GO:0048208=TAS, GO:0044281=TAS, GO:0006886=IEA, GO:0005829=TAS, GO:0043231=IDA, GO:0006888=TAS, GO:0019886=TAS, GO:0003674=ND, GO:0000139=IEA, GO:0005789=TAS, GO:0008270=IEA, GO:0044267=TAS, GO:0016044=TAS, GO:0043687=TAS, GO:0018279=TAS} COPII vesicle coating, ER to Golgi vesicle-mediated transport, antigen processing and presentation of exogenous peptide antigen via MHC class II, antigen processing and presentation of peptide antigen via MHC class I, cellular membrane organization, cellular protein metabolic process, intracellular protein transport, post-translational protein modification, protein N-linked glycosylation via asparagine, small molecule metabolic process COPII vesicle coat, ER to Golgi transport vesicle membrane, Golgi membrane, cytosol, endoplasmic reticulum membrane, intracellular membrane-bounded organelle, nucleolus, nucleus, perinuclear region of cytoplasm molecular_function, protein binding, zinc ion binding Human SEC24D Reactome UniProtKB {GO:0002474=Reactome:REACT_75820, GO:0012507=Reactome:REACT_75799, GO:0048471=GO_REF:0000039, GO:0030127=PMID:10329445, GO:0048208=Reactome:REACT_12507, GO:0044281=Reactome:REACT_111217, GO:0006886=GO_REF:0000002, GO:0005829=Reactome:REACT_75799, GO:0006888=Reactome:REACT_11203, GO:0019886=Reactome:REACT_121399, GO:0003674=GO_REF:0000015, GO:0000139=GO_REF:0000039, GO:0005789=Reactome:REACT_121121, GO:0008270=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0016044=Reactome:REACT_11123, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} O94855 Protein transport protein Sec24D protein 20130301 {GO:0002474=TAS, GO:0012507=TAS, GO:0048471=IEA, GO:0030127=NAS, GO:0048208=TAS, GO:0044281=TAS, GO:0006886=IEA, GO:0005829=TAS, GO:0006888=TAS, GO:0019886=TAS, GO:0003674=ND, GO:0000139=IEA, GO:0005789=TAS, GO:0008270=IEA, GO:0044267=TAS, GO:0016044=TAS, GO:0043687=TAS, GO:0018279=TAS} COPII vesicle coating, ER to Golgi vesicle-mediated transport, antigen processing and presentation of exogenous peptide antigen via MHC class II, antigen processing and presentation of peptide antigen via MHC class I, cellular membrane organization, cellular protein metabolic process, intracellular protein transport, post-translational protein modification, protein N-linked glycosylation via asparagine, small molecule metabolic process COPII vesicle coat, ER to Golgi transport vesicle membrane, Golgi membrane, cytosol, endoplasmic reticulum membrane, perinuclear region of cytoplasm molecular_function, zinc ion binding Human SEC31A HPA UniProtKB {GO:0005515=PMID:17214967, GO:0012507=Reactome:REACT_75799, GO:0030134=PMID:22802641, GO:0002474=Reactome:REACT_75820, GO:0048471=PMID:17196169, GO:0030127=PMID:10788476, GO:0005783=PMID:17196169, GO:0048208=Reactome:REACT_12507, GO:0015031=GO_REF:0000037, GO:0030968=Reactome:REACT_18356, GO:0005829=Reactome:REACT_75825, GO:0043231=GO_REF:0000052, GO:0006888=Reactome:REACT_11203, GO:0044432=PMID:22792322, GO:0019886=Reactome:REACT_121399, GO:0051592=PMID:17196169, GO:0005737=GO_REF:0000052, GO:0005789=Reactome:REACT_121121, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0016044=Reactome:REACT_11123, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426, GO:0048306=PMID:16957052} O94979 Protein transport protein Sec31A protein 20101115 {GO:0005515=IPI, GO:0012507=TAS, GO:0030134=IDA, GO:0002474=TAS, GO:0048471=IDA, GO:0030127=NAS, GO:0005783=IDA, GO:0048208=TAS, GO:0015031=IEA, GO:0030968=TAS, GO:0005829=TAS, GO:0043231=IDA, GO:0006888=TAS, GO:0044432=IDA, GO:0019886=TAS, GO:0051592=IDA, GO:0005737=IDA, GO:0005789=TAS, GO:0006987=TAS, GO:0044267=TAS, GO:0016044=TAS, GO:0043687=TAS, GO:0018279=TAS, GO:0048306=IPI} COPII vesicle coating, ER to Golgi vesicle-mediated transport, activation of signaling protein activity involved in unfolded protein response, antigen processing and presentation of exogenous peptide antigen via MHC class II, antigen processing and presentation of peptide antigen via MHC class I, cellular membrane organization, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, post-translational protein modification, protein N-linked glycosylation via asparagine, protein transport, response to calcium ion COPII vesicle coat, ER to Golgi transport vesicle, ER to Golgi transport vesicle membrane, cytoplasm, cytosol, endoplasmic reticulum, endoplasmic reticulum membrane, endoplasmic reticulum part, intracellular membrane-bounded organelle, perinuclear region of cytoplasm calcium-dependent protein binding, protein binding Human SEC31B MGI UniProtKB {GO:0044432=PMID:22792322, GO:0012507=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0016192=GO_REF:0000037, GO:0015031=GO_REF:0000037} Q9NQW1 Protein transport protein Sec31B protein 20130207 {GO:0044432=IDA, GO:0012507=IEA, GO:0005789=IEA, GO:0016192=IEA, GO:0015031=IEA} protein transport, vesicle-mediated transport ER to Golgi transport vesicle membrane, endoplasmic reticulum membrane, endoplasmic reticulum part Human SEC61A1 Reactome UniProtKB {GO:0005791=GO_REF:0000019, GO:0002474=Reactome:REACT_75820, GO:0016020=GO_REF:0000002, GO:0042590=Reactome:REACT_111119, GO:0002479=Reactome:REACT_111178, GO:0043022=GO_REF:0000024, GO:0030176=GO_REF:0000024, GO:0034341=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0015031=GO_REF:0000002, GO:0045047=GO_REF:0000024} P61619 Protein transport protein Sec61 subunit alpha isoform 1 protein 20130301 {GO:0005791=IEA, GO:0002474=TAS, GO:0016020=IEA, GO:0042590=TAS, GO:0002479=TAS, GO:0043022=ISS, GO:0030176=ISS, GO:0034341=IEA, GO:0016021=IEA, GO:0015031=IEA, GO:0045047=ISS} antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, protein targeting to ER, protein transport, response to interferon-gamma integral to endoplasmic reticulum membrane, integral to membrane, membrane, rough endoplasmic reticulum ribosome binding Human SEC61A2 Reactome UniProtKB {GO:0002474=Reactome:REACT_75820, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0016020=GO_REF:0000002, GO:0042590=Reactome:REACT_111119, GO:0005789=GO_REF:0000039, GO:0002479=Reactome:REACT_111178, GO:0043022=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0015031=GO_REF:0000037} Q9H9S3 Protein transport protein Sec61 subunit alpha isoform 2 protein 20130301 {GO:0002474=TAS, GO:0003674=ND, GO:0008150=ND, GO:0016020=IEA, GO:0042590=TAS, GO:0005789=IEA, GO:0002479=TAS, GO:0043022=IEA, GO:0016021=IEA, GO:0015031=IEA} antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, biological_process, protein transport endoplasmic reticulum membrane, integral to membrane, membrane molecular_function, ribosome binding Human SEC61B Reactome UniProtKB {GO:0005515=PMID:18555783, GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0030970=PMID:17215517, GO:0048408=PMID:19602593, GO:0006614=Reactome:REACT_115902, GO:0042590=Reactome:REACT_111119, GO:0030433=PMID:8945469, GO:0031205=GO_REF:0000024, GO:0006412=Reactome:REACT_1014, GO:0002479=Reactome:REACT_111178, GO:0016021=PMID:8107851, GO:0044267=Reactome:REACT_17015, GO:0000060=PMID:17215517} P60468 Protein transport protein Sec61 subunit beta protein 20130213 {GO:0005515=IPI, GO:0002474=TAS, GO:0010467=TAS, GO:0030970=IMP, GO:0048408=IPI, GO:0006614=TAS, GO:0042590=TAS, GO:0030433=IDA, GO:0031205=ISS, GO:0006412=TAS, GO:0002479=TAS, GO:0016021=NAS, GO:0044267=TAS, GO:0000060=IMP} ER-associated protein catabolic process, SRP-dependent cotranslational protein targeting to membrane, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, cellular protein metabolic process, gene expression, protein import into nucleus, translocation, retrograde protein transport, ER to cytosol, translation endoplasmic reticulum Sec complex, integral to membrane epidermal growth factor binding, protein binding Human SEC61G Reactome UniProtKB {GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0006614=Reactome:REACT_115902, GO:0042590=Reactome:REACT_111119, GO:0005575=GO_REF:0000015, GO:0045047=GO_REF:0000024, GO:0006412=Reactome:REACT_1014, GO:0015450=GO_REF:0000002, GO:0008565=GO_REF:0000024, GO:0005789=GO_REF:0000039, GO:0002479=Reactome:REACT_111178, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015} P60059 Protein transport protein Sec61 subunit gamma protein 20130213 {GO:0002474=TAS, GO:0010467=TAS, GO:0006614=TAS, GO:0042590=TAS, GO:0005575=ND, GO:0045047=ISS, GO:0006412=TAS, GO:0015450=IEA, GO:0008565=ISS, GO:0005789=IEA, GO:0002479=TAS, GO:0016021=IEA, GO:0044267=TAS} SRP-dependent cotranslational protein targeting to membrane, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, cellular protein metabolic process, gene expression, protein targeting to ER, translation cellular_component, endoplasmic reticulum membrane, integral to membrane P-P-bond-hydrolysis-driven protein transmembrane transporter activity, protein transporter activity Human SEC62 HPA UniProtKB {GO:0005791=GO_REF:0000024, GO:0016235=GO_REF:0000052, GO:0005783=GO_REF:0000052, GO:0006613=PMID:9020021, GO:0008565=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0004872=PMID:9020021, GO:0045111=GO_REF:0000052, GO:0016021=GO_REF:0000037} Q99442 Translocation protein SEC62 protein 20090616 {GO:0005791=ISS, GO:0016235=IDA, GO:0005783=IDA, GO:0006613=TAS, GO:0008565=IEA, GO:0005789=IEA, GO:0004872=TAS, GO:0045111=IDA, GO:0016021=IEA} cotranslational protein targeting to membrane aggresome, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, intermediate filament cytoskeleton, rough endoplasmic reticulum protein transporter activity, receptor activity Human SEC63 PINC UniProtKB {GO:0005783=PMID:10799540, GO:0006612=PMID:10799540, GO:0008565=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0004872=PMID:10799540, GO:0016021=GO_REF:0000037, GO:0031204=GO_REF:0000002} Q9UGP8 Translocation protein SEC63 homolog protein 20050308 {GO:0005783=TAS, GO:0006612=TAS, GO:0008565=IEA, GO:0005789=IEA, GO:0004872=TAS, GO:0016021=IEA, GO:0031204=IEA} posttranslational protein targeting to membrane, translocation, protein targeting to membrane endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane protein transporter activity, receptor activity Human SECISBP2 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0003730=PMID:16962588, GO:0006412=GO_REF:0000037} Q96T21 Selenocysteine insertion sequence-binding protein 2 protein 20080428 {GO:0005739=IEA, GO:0005634=IEA, GO:0003730=IDA, GO:0006412=IEA} translation mitochondrion, nucleus mRNA 3'-UTR binding Human SECISBP2L null null {} null null null null {} null null null SECTM1 GOC UniProtKB {GO:0007165=PMID:12761501, GO:0006955=PMID:9480746, GO:0005794=PMID:9480746, GO:0005886=GO_REF:0000039, GO:0007498=PMID:9480746, GO:0004871=PMID:12761501, GO:0016021=GO_REF:0000037, GO:0043123=PMID:12761501, GO:0005615=PMID:9480746, GO:0005125=PMID:9480746} Q8WVN6 Secreted and transmembrane protein 1 protein 20130413 {GO:0007165=IMP, GO:0006955=TAS, GO:0005794=TAS, GO:0005886=IEA, GO:0007498=TAS, GO:0004871=IMP, GO:0016021=IEA, GO:0043123=IMP, GO:0005615=TAS, GO:0005125=TAS} immune response, mesoderm development, positive regulation of I-kappaB kinase/NF-kappaB cascade, signal transduction Golgi apparatus, extracellular space, integral to membrane, plasma membrane cytokine activity, signal transducer activity Human SEH1L Reactome UniProtKB {GO:0022415=Reactome:REACT_6361, GO:0000236=Reactome:REACT_682, GO:0005975=Reactome:REACT_474, GO:0019221=Reactome:REACT_25229, GO:0044281=Reactome:REACT_111217, GO:0005635=Reactome:REACT_115827, GO:0015031=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0010827=Reactome:REACT_6804, GO:0008645=Reactome:REACT_9441, GO:0005829=Reactome:REACT_150414, GO:0051315=PMID:17363900, GO:0015758=Reactome:REACT_212, GO:0031080=PMID:15146057, GO:0000087=Reactome:REACT_910, GO:0000777=GO_REF:0000039, GO:0016032=Reactome:REACT_6256, GO:0000776=PMID:15146057, GO:0006999=PMID:15146057, GO:0007080=PMID:17363900, GO:0051028=GO_REF:0000037, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} Q96EE3 Nucleoporin SEH1 protein 20130301 {GO:0022415=TAS, GO:0000236=TAS, GO:0005975=TAS, GO:0019221=TAS, GO:0044281=TAS, GO:0005635=TAS, GO:0015031=IEA, GO:0055085=TAS, GO:0010827=TAS, GO:0008645=TAS, GO:0005829=TAS, GO:0051315=IMP, GO:0015758=TAS, GO:0031080=NAS, GO:0000087=TAS, GO:0000777=IEA, GO:0016032=TAS, GO:0000776=IDA, GO:0006999=IMP, GO:0007080=IMP, GO:0051028=IEA, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation, carbohydrate metabolic process, cell division, cytokine-mediated signaling pathway, glucose transport, hexose transport, mRNA transport, mitotic anaphase, mitotic cell cycle, mitotic metaphase plate congression, mitotic prometaphase, nuclear pore organization, protein transport, regulation of glucose transport, small molecule metabolic process, transmembrane transport, viral reproduction, viral reproductive process condensed chromosome kinetochore, cytosol, kinetochore, nuclear envelope, nuclear pore outer ring Human SEL1L UniProtKB UniProtKB {GO:0005515=PMID:18502753, GO:0034976=GO_REF:0000019, GO:0007219=GO_REF:0000037, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000029} Q9UBV2 Protein sel-1 homolog 1 protein 20120708 {GO:0005515=IPI, GO:0034976=IEA, GO:0007219=IEA, GO:0005789=IEA, GO:0016021=NAS} Notch signaling pathway, response to endoplasmic reticulum stress endoplasmic reticulum membrane, integral to membrane protein binding Human UniProtKB:Q96DZ1-1 SEL1L2 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q5TEA6 Protein sel-1 homolog 2 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 SEL1L3 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q68CR1 Protein sel-1 homolog 3 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 SELE InterPro UniProtKB {GO:0005515=PMID:18606703, GO:0048471=PMID:12960351, GO:0019722=PMID:12960351, GO:0005886=PMID:2466335, GO:0007202=PMID:12960351, GO:0005615=PMID:9290466, GO:0050901=PMID:18029551, GO:0006954=PMID:2466335, GO:0070492=PMID:7680663, GO:0043274=PMID:12960351, GO:0007159=PMID:7680663, GO:0032496=PMID:18029551, GO:0033691=PMID:7680663, GO:0007155=GO_REF:0000002, GO:0070555=PMID:8609175, GO:0007157=PMID:18029551, GO:0030029=PMID:8609175, GO:0002523=PMID:18029551, GO:0050727=PMID:18029551, GO:0005905=PMID:18029551, GO:0016020=GO_REF:0000002, GO:0005901=PMID:12960351, GO:0002687=GO_REF:0000019, GO:0030246=GO_REF:0000002, GO:0045121=PMID:18029551, GO:0034612=PMID:18029551, GO:0030863=PMID:8609175, GO:0016021=GO_REF:0000037, GO:0002092=PMID:9312078, GO:0004888=PMID:12960351} Q5TI75 E-selectin protein 20130413 {GO:0005515=IPI, GO:0048471=IDA, GO:0019722=TAS, GO:0005886=TAS, GO:0007202=IMP, GO:0005615=IDA, GO:0050901=IMP, GO:0006954=TAS, GO:0070492=IDA, GO:0043274=IDA, GO:0007159=IDA, GO:0032496=TAS, GO:0033691=IDA, GO:0007155=IEA, GO:0070555=IDA, GO:0007157=IMP, GO:0030029=IDA, GO:0002523=TAS, GO:0050727=TAS, GO:0005905=IDA, GO:0016020=IEA, GO:0005901=IDA, GO:0002687=IEA, GO:0030246=IEA, GO:0045121=IDA, GO:0034612=TAS, GO:0030863=IDA, GO:0016021=IEA, GO:0002092=IDA, GO:0004888=IMP} actin filament-based process, activation of phospholipase C activity, calcium-mediated signaling, cell adhesion, heterophilic cell-cell adhesion, inflammatory response, leukocyte cell-cell adhesion, leukocyte migration involved in inflammatory response, leukocyte tethering or rolling, positive regulation of leukocyte migration, positive regulation of receptor internalization, regulation of inflammatory response, response to interleukin-1, response to lipopolysaccharide, response to tumor necrosis factor caveola, coated pit, cortical cytoskeleton, extracellular space, integral to membrane, membrane, membrane raft, perinuclear region of cytoplasm, plasma membrane carbohydrate binding, oligosaccharide binding, phospholipase binding, protein binding, sialic acid binding, transmembrane signaling receptor activity Human InterPro:IPR001304 SELENBP1 HPA UniProtKB {GO:0008430=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0015031=GO_REF:0000037, GO:0005829=GO_REF:0000039} Q13228 Selenium-binding protein 1 protein 20081203 {GO:0008430=IEA, GO:0016020=IEA, GO:0005730=IDA, GO:0015031=IEA, GO:0005829=IEA} protein transport cytosol, membrane, nucleolus selenium binding Human SELL BHF-UCL UniProtKB {GO:0005515=PMID:18606703, GO:0005886=Reactome:REACT_12081, GO:0002020=PMID:17548643, GO:0050900=Reactome:REACT_12051, GO:0005887=PMID:1692315, GO:0007596=Reactome:REACT_604, GO:0043208=PMID:7680663, GO:0050776=Reactome:REACT_11152, GO:0030246=GO_REF:0000002, GO:0033198=GO_REF:0000019, GO:0007155=GO_REF:0000037, GO:0050839=GO_REF:0000019, GO:0008201=PMID:7680663, GO:0009897=GO_REF:0000019} P14151 L-selectin protein 20110217 {GO:0005515=IPI, GO:0005886=TAS, GO:0002020=IPI, GO:0050900=TAS, GO:0005887=TAS, GO:0007596=TAS, GO:0043208=TAS, GO:0050776=TAS, GO:0030246=IEA, GO:0033198=IEA, GO:0007155=IEA, GO:0050839=IEA, GO:0008201=TAS, GO:0009897=IEA} blood coagulation, cell adhesion, leukocyte migration, regulation of immune response, response to ATP external side of plasma membrane, integral to plasma membrane, plasma membrane carbohydrate binding, cell adhesion molecule binding, glycosphingolipid binding, heparin binding, protease binding, protein binding Human UniProtKB:P78325 SELP HPA UniProtKB {GO:0005515=PMID:18606703, GO:0031088=Reactome:REACT_21266, GO:0005886=Reactome:REACT_21394, GO:0005634=GO_REF:0000052, GO:0042806=PMID:7680663, GO:0050900=Reactome:REACT_12051, GO:0005615=PMID:9290466, GO:0050901=GO_REF:0000019, GO:0033623=PMID:17632516, GO:0005737=GO_REF:0000052, GO:0006954=GO_REF:0000019, GO:0001948=GO_REF:0000019, GO:0070492=PMID:7680663, GO:0043208=PMID:7680663, GO:0010572=GO_REF:0000019, GO:0007159=PMID:7680663, GO:0032496=PMID:16514062, GO:0031092=Reactome:REACT_21394, GO:0033691=GO_REF:0000019, GO:0007155=GO_REF:0000002, GO:0008201=PMID:7680663, GO:0007157=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0030168=Reactome:REACT_798, GO:0014068=PMID:17632516, GO:0001530=PMID:16514062, GO:0050829=PMID:16514062, GO:0016020=GO_REF:0000002, GO:0005887=PMID:1701178, GO:0007596=Reactome:REACT_604, GO:0002687=GO_REF:0000019, GO:0002576=Reactome:REACT_318, GO:0030246=GO_REF:0000002, GO:0009897=GO_REF:0000019, GO:0048306=GO_REF:0000019} Q5R349 P-selectin protein 20080205 {GO:0005515=IPI, GO:0031088=TAS, GO:0005886=TAS, GO:0005634=IDA, GO:0042806=IDA, GO:0050900=TAS, GO:0005615=IDA, GO:0050901=IEA, GO:0033623=IMP, GO:0005737=IDA, GO:0006954=IEA, GO:0001948=IEA, GO:0070492=IDA, GO:0043208=TAS, GO:0010572=IEA, GO:0007159=IDA, GO:0032496=IC, GO:0031092=TAS, GO:0033691=IEA, GO:0007155=IEA, GO:0008201=IDA, GO:0007157=IEA, GO:0005730=IDA, GO:0030168=TAS, GO:0014068=IDA, GO:0001530=IMP, GO:0050829=IC, GO:0016020=IEA, GO:0005887=TAS, GO:0007596=TAS, GO:0002687=IEA, GO:0002576=TAS, GO:0030246=IEA, GO:0009897=IEA, GO:0048306=IEA} blood coagulation, cell adhesion, defense response to Gram-negative bacterium, heterophilic cell-cell adhesion, inflammatory response, leukocyte cell-cell adhesion, leukocyte migration, leukocyte tethering or rolling, platelet activation, platelet degranulation, positive regulation of leukocyte migration, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of platelet activation, regulation of integrin activation, response to lipopolysaccharide cytoplasm, external side of plasma membrane, extracellular space, integral to plasma membrane, membrane, nucleolus, nucleus, plasma membrane, platelet alpha granule membrane, platelet dense granule membrane calcium-dependent protein binding, carbohydrate binding, fucose binding, glycoprotein binding, glycosphingolipid binding, heparin binding, lipopolysaccharide binding, oligosaccharide binding, protein binding, sialic acid binding Human SELPLG Reactome UniProtKB {GO:0051635=PMID:10834846, GO:0005886=Reactome:REACT_12081, GO:0016020=PMID:7505206, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:7505206, GO:0005102=PMID:7505206, GO:0071354=PMID:9486531, GO:0016021=PMID:7541799, GO:0050900=Reactome:REACT_12051, GO:0007155=PMID:7505206, GO:0050901=GO_REF:0000002, GO:0050902=GO_REF:0000024} Q14242 P-selectin glycoprotein ligand 1 protein 20071111 {GO:0051635=TAS, GO:0005886=TAS, GO:0016020=TAS, GO:0007596=TAS, GO:0005887=TAS, GO:0005102=NAS, GO:0071354=IDA, GO:0016021=TAS, GO:0050900=TAS, GO:0007155=TAS, GO:0050901=IEA, GO:0050902=ISS} blood coagulation, cell adhesion, cellular response to interleukin-6, leukocyte adhesive activation, leukocyte migration, leukocyte tethering or rolling integral to membrane, integral to plasma membrane, membrane, plasma membrane bacterial cell surface binding, receptor binding Human SELRC1 null null {} null null null null {} null null null SEMA3A BHF-UCL UniProtKB {GO:0030424=GO_REF:0000019, GO:0048843=GO_REF:0000019, GO:0006915=GO_REF:0000019, GO:0005576=Reactome:REACT_19321, GO:0048485=PMID:19909241, GO:0030425=GO_REF:0000019, GO:0048813=GO_REF:0000019, GO:0045499=PMID:19909241, GO:0007413=GO_REF:0000019, GO:0021772=PMID:22416012, GO:0048841=PMID:18053124, GO:0002027=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0007411=PMID:19909241, GO:0060666=GO_REF:0000019, GO:0071526=PMID:19909241, GO:0048880=PMID:19909241, GO:0004872=GO_REF:0000002, GO:0010633=GO_REF:0000019} Q14563 Semaphorin-3A protein 20110907 {GO:0030424=IEA, GO:0048843=IEA, GO:0006915=IEA, GO:0005576=TAS, GO:0048485=TAS, GO:0030425=IEA, GO:0048813=IEA, GO:0045499=TAS, GO:0007413=IEA, GO:0021772=IMP, GO:0048841=IDA, GO:0002027=IEA, GO:0016020=IEA, GO:0007411=TAS, GO:0060666=IEA, GO:0071526=TAS, GO:0048880=TAS, GO:0004872=IEA, GO:0010633=IEA} apoptotic process, axon guidance, axonal fasciculation, dendrite morphogenesis, dichotomous subdivision of terminal units involved in salivary gland branching, negative regulation of axon extension involved in axon guidance, negative regulation of epithelial cell migration, olfactory bulb development, regulation of axon extension involved in axon guidance, regulation of heart rate, semaphorin-plexin signaling pathway, sensory system development, sympathetic nervous system development axon, dendrite, extracellular region, membrane chemorepellent activity, receptor activity Human SEMA3B PINC UniProtKB {GO:0016020=GO_REF:0000002, GO:0007411=PMID:8633026, GO:0005783=GO_REF:0000039, GO:0007267=PMID:8633026, GO:0005576=GO_REF:0000039, GO:0004872=GO_REF:0000002} Q13214 Semaphorin-3B protein 20030904 {GO:0016020=IEA, GO:0007411=TAS, GO:0005783=IEA, GO:0007267=TAS, GO:0005576=IEA, GO:0004872=IEA} axon guidance, cell-cell signaling endoplasmic reticulum, extracellular region, membrane receptor activity Human SEMA3C PINC UniProtKB {GO:0042493=PMID:9405678, GO:0001756=GO_REF:0000019, GO:0001755=GO_REF:0000019, GO:0003350=GO_REF:0000019, GO:0007275=GO_REF:0000002, GO:0003215=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0003151=GO_REF:0000019, GO:0006955=PMID:9168980, GO:0016020=GO_REF:0000002, GO:0007411=GO_REF:0000024, GO:0001974=GO_REF:0000019, GO:0060666=GO_REF:0000019, GO:0021915=GO_REF:0000019, GO:0060174=GO_REF:0000019, GO:0004872=GO_REF:0000002, GO:0030215=GO_REF:0000019} Q99985 Semaphorin-3C protein 20031119 {GO:0042493=TAS, GO:0001756=IEA, GO:0001755=IEA, GO:0003350=IEA, GO:0007275=IEA, GO:0003215=IEA, GO:0009791=IEA, GO:0005615=IEA, GO:0003151=IEA, GO:0006955=TAS, GO:0016020=IEA, GO:0007411=ISS, GO:0001974=IEA, GO:0060666=IEA, GO:0021915=IEA, GO:0060174=IEA, GO:0004872=IEA, GO:0030215=IEA} axon guidance, blood vessel remodeling, cardiac right ventricle morphogenesis, dichotomous subdivision of terminal units involved in salivary gland branching, immune response, limb bud formation, multicellular organismal development, neural crest cell migration, neural tube development, outflow tract morphogenesis, post-embryonic development, pulmonary myocardium development, response to drug, somitogenesis extracellular space, membrane receptor activity, semaphorin receptor binding Human SEMA3E Reactome UniProtKB {GO:0001569=GO_REF:0000024, GO:0008360=GO_REF:0000024, GO:0002040=GO_REF:0000024, GO:0005576=Reactome:REACT_19273, GO:0005615=PMID:9515811, GO:2000249=GO_REF:0000024, GO:0050808=GO_REF:0000024, GO:0016020=GO_REF:0000002, GO:0007411=Reactome:REACT_18266, GO:0016525=GO_REF:0000024, GO:0071526=GO_REF:0000024, GO:0004872=GO_REF:0000002, GO:0001953=GO_REF:0000024} O15041 Semaphorin-3E protein 20090331 {GO:0001569=ISS, GO:0008360=ISS, GO:0002040=ISS, GO:0005576=TAS, GO:0005615=TAS, GO:2000249=ISS, GO:0050808=ISS, GO:0016020=IEA, GO:0007411=TAS, GO:0016525=ISS, GO:0071526=ISS, GO:0004872=IEA, GO:0001953=ISS} axon guidance, negative regulation of angiogenesis, negative regulation of cell-matrix adhesion, patterning of blood vessels, regulation of actin cytoskeleton reorganization, regulation of cell shape, semaphorin-plexin signaling pathway, sprouting angiogenesis, synapse organization extracellular region, extracellular space, membrane receptor activity Human SEMA3F MGI UniProtKB {GO:0045499=PMID:15814794, GO:0016020=GO_REF:0000002, GO:0007411=PMID:15814794, GO:0001755=GO_REF:0000019, GO:0048843=GO_REF:0000019, GO:0007275=GO_REF:0000002, GO:0004872=GO_REF:0000002, GO:0005615=PMID:8786119} Q13275 Semaphorin-3F protein 20101228 {GO:0045499=IDA, GO:0016020=IEA, GO:0007411=IDA, GO:0001755=IEA, GO:0048843=IEA, GO:0007275=IEA, GO:0004872=IEA, GO:0005615=TAS} axon guidance, multicellular organismal development, negative regulation of axon extension involved in axon guidance, neural crest cell migration extracellular space, membrane chemorepellent activity, receptor activity Human SEMA4A Reactome UniProtKB {GO:0010594=GO_REF:0000019, GO:0005886=Reactome:REACT_19408, GO:0045063=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0008360=GO_REF:0000019, GO:0016525=GO_REF:0000019, GO:0071526=GO_REF:0000019, GO:0004872=GO_REF:0000002, GO:0001525=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0007409=GO_REF:0000019} Q9H3S1 Semaphorin-4A protein 20070603 {GO:0010594=IEA, GO:0005886=TAS, GO:0045063=IEA, GO:0007411=TAS, GO:0008360=IEA, GO:0016525=IEA, GO:0071526=IEA, GO:0004872=IEA, GO:0001525=IEA, GO:0016021=IEA, GO:0007409=IEA} T-helper 1 cell differentiation, angiogenesis, axon guidance, axonogenesis, negative regulation of angiogenesis, regulation of cell shape, regulation of endothelial cell migration, semaphorin-plexin signaling pathway integral to membrane, plasma membrane receptor activity Human SEMA4B UniProtKB UniProtKB {GO:0007275=GO_REF:0000002, GO:0004872=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0007399=GO_REF:0000037} Q9NPR2 Semaphorin-4B protein 20130413 {GO:0007275=IEA, GO:0004872=IEA, GO:0016021=IEA, GO:0030154=IEA, GO:0007399=IEA} cell differentiation, multicellular organismal development, nervous system development integral to membrane receptor activity Human UniProtKB-KW:KW-0221 SEMA4C UniProtKB UniProtKB {GO:0021535=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000037, GO:0001843=GO_REF:0000024, GO:0014069=GO_REF:0000024, GO:0021549=GO_REF:0000019, GO:0032874=PMID:17498836, GO:0042692=PMID:17498836, GO:0045211=GO_REF:0000037, GO:0071526=GO_REF:0000024, GO:0030672=GO_REF:0000024, GO:0004872=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q9C0C4 Semaphorin-4C protein 20120109 {GO:0021535=ISS, GO:0030054=IEA, GO:0005886=IEA, GO:0001843=ISS, GO:0014069=ISS, GO:0021549=IEA, GO:0032874=IDA, GO:0042692=IDA, GO:0045211=IEA, GO:0071526=ISS, GO:0030672=ISS, GO:0004872=IEA, GO:0016021=IEA} cell migration in hindbrain, cerebellum development, muscle cell differentiation, neural tube closure, positive regulation of stress-activated MAPK cascade, semaphorin-plexin signaling pathway cell junction, integral to membrane, plasma membrane, postsynaptic density, postsynaptic membrane, synaptic vesicle membrane receptor activity Human UniProtKB:Q64151 SEMA4D BHF-UCL UniProtKB {GO:0005515=PMID:20877282, GO:1900220=GO_REF:0000024, GO:0043931=PMID:22019888, GO:0005886=Reactome:REACT_19398, GO:0008360=PMID:20877282, GO:0050732=GO_REF:0000024, GO:0050731=GO_REF:0000024, GO:0005615=GO_REF:0000024, GO:0010693=PMID:22019888, GO:0048672=PMID:19788569, GO:0006955=PMID:8876214, GO:0007411=Reactome:REACT_18266, GO:0004872=PMID:15613544, GO:0007155=PMID:8876214, GO:0043066=PMID:8876214, GO:0030335=GO_REF:0000024, GO:0005102=PMID:11254688, GO:0014068=PMID:16055703, GO:0000122=PMID:22019888, GO:0048814=PMID:19788569, GO:0031344=PMID:20877282, GO:0045668=GO_REF:0000024, GO:0032321=GO_REF:0000024, GO:0005887=PMID:8876214, GO:0070486=PMID:8876214, GO:0071526=PMID:19788569, GO:0001934=PMID:16055703, GO:0030215=GO_REF:0000024, GO:0050772=GO_REF:0000019, GO:0004888=PMID:20877282} Q92854 Semaphorin-4D protein 20111208 {GO:0005515=IPI, GO:1900220=ISS, GO:0043931=IMP, GO:0005886=TAS, GO:0008360=IMP, GO:0050732=ISS, GO:0050731=ISS, GO:0005615=ISS, GO:0010693=IMP, GO:0048672=IMP, GO:0006955=TAS, GO:0007411=TAS, GO:0004872=IDA, GO:0007155=TAS, GO:0043066=TAS, GO:0030335=ISS, GO:0005102=IDA, GO:0014068=IMP, GO:0000122=IMP, GO:0048814=IMP, GO:0031344=IMP, GO:0045668=ISS, GO:0032321=ISS, GO:0005887=IDA, GO:0070486=IMP, GO:0071526=IMP, GO:0001934=IDA, GO:0030215=ISS, GO:0050772=IEA, GO:0004888=IMP} axon guidance, cell adhesion, immune response, leukocyte aggregation, negative regulation of alkaline phosphatase activity, negative regulation of apoptotic process, negative regulation of osteoblast differentiation, negative regulation of peptidyl-tyrosine phosphorylation, negative regulation of transcription from RNA polymerase II promoter, ossification involved in bone maturation, positive regulation of Rho GTPase activity, positive regulation of axonogenesis, positive regulation of cell migration, positive regulation of collateral sprouting, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of protein phosphorylation, regulation of cell projection organization, regulation of cell shape, regulation of dendrite morphogenesis, semaphorin-plexin signaling pathway, semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis extracellular space, integral to plasma membrane, plasma membrane protein binding, receptor activity, receptor binding, semaphorin receptor binding, transmembrane signaling receptor activity Human UniProtKB:O09126 SEMA4F LIFEdb UniProtKB {GO:0031290=GO_REF:0000019, GO:0005886=PMID:10051670, GO:0016020=PMID:10051670, GO:0005783=GO_REF:0000054, GO:0005887=PMID:10051670, GO:0030517=GO_REF:0000019, GO:0007411=PMID:10051670, GO:0045211=GO_REF:0000019, GO:0007267=PMID:10051670, GO:0004872=GO_REF:0000002, GO:0016021=GO_REF:0000002, GO:0007399=PMID:10051670} O95754 Semaphorin-4F protein 20100607 {GO:0031290=IEA, GO:0005886=TAS, GO:0016020=TAS, GO:0005783=IDA, GO:0005887=TAS, GO:0030517=IEA, GO:0007411=TAS, GO:0045211=IEA, GO:0007267=TAS, GO:0004872=IEA, GO:0016021=IEA, GO:0007399=TAS} axon guidance, cell-cell signaling, negative regulation of axon extension, nervous system development, retinal ganglion cell axon guidance endoplasmic reticulum, integral to membrane, integral to plasma membrane, membrane, plasma membrane, postsynaptic membrane receptor activity Human SEMA4G UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0004872=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0007399=GO_REF:0000037} Q9NTN9 Semaphorin-4G protein 20130413 {GO:0005886=IEA, GO:0004872=IEA, GO:0016021=IEA, GO:0030154=IEA, GO:0007399=IEA} cell differentiation, nervous system development integral to membrane, plasma membrane receptor activity Human UniProtKB-SubCell:SL-0039 SEMA5A Reactome UniProtKB {GO:0001569=GO_REF:0000019, GO:0005886=Reactome:REACT_19322, GO:0007411=Reactome:REACT_18266, GO:0007267=PMID:9464278, GO:0016021=GO_REF:0000019, GO:0007155=PMID:9049630, GO:0008046=GO_REF:0000019, GO:0007399=PMID:9464278} Q13591 Semaphorin-5A protein 20090904 {GO:0001569=IEA, GO:0005886=TAS, GO:0007411=TAS, GO:0007267=TAS, GO:0016021=IEA, GO:0007155=TAS, GO:0008046=IEA, GO:0007399=TAS} axon guidance, cell adhesion, cell-cell signaling, nervous system development, patterning of blood vessels integral to membrane, plasma membrane axon guidance receptor activity Human SEMA5B UniProtKB UniProtKB {GO:0007275=GO_REF:0000002, GO:0004872=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0007399=GO_REF:0000037} Q9P283 Semaphorin-5B protein 20130413 {GO:0007275=IEA, GO:0004872=IEA, GO:0016021=IEA, GO:0030154=IEA, GO:0007399=IEA} cell differentiation, multicellular organismal development, nervous system development integral to membrane receptor activity Human UniProtKB-KW:KW-0221 SEMA6A Reactome UniProtKB {GO:0005515=PMID:10993894, GO:0030424=PMID:10993894, GO:2001224=GO_REF:0000019, GO:0006915=PMID:10993894, GO:0007275=GO_REF:0000002, GO:0007399=PMID:10993894, GO:0051642=GO_REF:0000019, GO:0005887=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0007010=PMID:10993894, GO:0071526=GO_REF:0000019, GO:0009887=PMID:10993894, GO:0030215=GO_REF:0000019, GO:0004872=GO_REF:0000002, GO:0016021=PMID:10993894, GO:0001764=GO_REF:0000019, GO:0007166=PMID:10993894, GO:0004888=GO_REF:0000019} Q9H2E6 Semaphorin-6A protein 20090331 {GO:0005515=IPI, GO:0030424=NAS, GO:2001224=IEA, GO:0006915=NAS, GO:0007275=IEA, GO:0007399=NAS, GO:0051642=IEA, GO:0005887=IEA, GO:0007411=TAS, GO:0007010=NAS, GO:0071526=IEA, GO:0009887=NAS, GO:0030215=IEA, GO:0004872=IEA, GO:0016021=NAS, GO:0001764=IEA, GO:0007166=NAS, GO:0004888=IEA} apoptotic process, axon guidance, cell surface receptor signaling pathway, centrosome localization, cytoskeleton organization, multicellular organismal development, nervous system development, neuron migration, organ morphogenesis, positive regulation of neuron migration, semaphorin-plexin signaling pathway axon, integral to membrane, integral to plasma membrane protein binding, receptor activity, semaphorin receptor binding, transmembrane signaling receptor activity Human SEMA6D HPA UniProtKB {GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0007411=Reactome:REACT_18266, GO:0030215=GO_REF:0000019, GO:0007275=GO_REF:0000002, GO:0004872=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q8NFY4 Semaphorin-6D protein 20111111 {GO:0005794=IDA, GO:0005886=IDA, GO:0007411=TAS, GO:0030215=IEA, GO:0007275=IEA, GO:0004872=IEA, GO:0016021=IEA} axon guidance, multicellular organismal development Golgi apparatus, integral to membrane, plasma membrane receptor activity, semaphorin receptor binding Human SEMA7A IntAct UniProtKB {GO:0005515=PMID:20727575, GO:0005886=Reactome:REACT_19190, GO:0050727=GO_REF:0000024, GO:0045773=PMID:12879062, GO:0007275=GO_REF:0000002, GO:0031225=GO_REF:0000037, GO:0006955=PMID:9721204, GO:0005178=GO_REF:0000019, GO:0006954=GO_REF:0000037, GO:0007411=Reactome:REACT_18266, GO:0007229=PMID:12879062, GO:0060907=GO_REF:0000024, GO:0004872=GO_REF:0000002, GO:0070374=PMID:12879062, GO:0009897=GO_REF:0000024} O75326 Semaphorin-7A protein 20130415 {GO:0005515=IPI, GO:0005886=TAS, GO:0050727=ISS, GO:0045773=IDA, GO:0007275=IEA, GO:0031225=IEA, GO:0006955=TAS, GO:0005178=IEA, GO:0006954=IEA, GO:0007411=TAS, GO:0007229=IDA, GO:0060907=ISS, GO:0004872=IEA, GO:0070374=IDA, GO:0009897=ISS} axon guidance, immune response, inflammatory response, integrin-mediated signaling pathway, multicellular organismal development, positive regulation of ERK1 and ERK2 cascade, positive regulation of axon extension, positive regulation of macrophage cytokine production, regulation of inflammatory response anchored to membrane, external side of plasma membrane, plasma membrane integrin binding, protein binding, receptor activity Human UniProtKB:O60486 SEMG1 Reactome UniProtKB {GO:0005515=PMID:15590901, GO:0007320=PMID:2912989, GO:0019953=GO_REF:0000002, GO:0005198=GO_REF:0000002, GO:0005576=Reactome:REACT_75905, GO:0030141=GO_REF:0000002, GO:0005615=PMID:1517240} P04279 Semenogelin-1 protein 20130213 {GO:0005515=IPI, GO:0007320=TAS, GO:0019953=IEA, GO:0005198=IEA, GO:0005576=TAS, GO:0030141=IEA, GO:0005615=TAS} insemination, sexual reproduction extracellular region, extracellular space, secretory granule protein binding, structural molecule activity Human SEMG2 PINC UniProtKB {GO:0019953=GO_REF:0000002, GO:0005198=GO_REF:0000002, GO:0030141=GO_REF:0000002, GO:0005615=PMID:1517240} Q02383 Semenogelin-2 protein 20030904 {GO:0019953=IEA, GO:0005198=IEA, GO:0030141=IEA, GO:0005615=TAS} sexual reproduction extracellular space, secretory granule structural molecule activity Human SENP1 HPA UniProtKB {GO:0005737=GO_REF:0000039, GO:0004175=PMID:10652325, GO:0006919=PMID:1087798, GO:0016926=GO_REF:0000024, GO:0045944=PMID:17981124, GO:0006508=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0016929=GO_REF:0000024, GO:0032435=GO_REF:0000019, GO:0097190=PMID:1087798, GO:0010724=GO_REF:0000019} Q9P0U3 Sentrin-specific protease 1 protein 20101115 {GO:0005737=IEA, GO:0004175=TAS, GO:0006919=IMP, GO:0016926=ISS, GO:0045944=IGI, GO:0006508=IEA, GO:0005634=IDA, GO:0016929=ISS, GO:0032435=IEA, GO:0097190=IMP, GO:0010724=IEA} activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic signaling pathway, negative regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of transcription from RNA polymerase II promoter, protein desumoylation, proteolysis, regulation of definitive erythrocyte differentiation cytoplasm, nucleus SUMO-specific protease activity, endopeptidase activity Human SENP2 IntAct UniProtKB {GO:0005515=PMID:20098747, GO:0032091=GO_REF:0000019, GO:0031965=GO_REF:0000039, GO:0030111=PMID:11896061, GO:0016926=GO_REF:0000024, GO:0019904=GO_REF:0000019, GO:0016929=PMID:11896061, GO:0015031=GO_REF:0000037, GO:0009950=GO_REF:0000019, GO:0035562=GO_REF:0000019, GO:0007507=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0005643=PMID:12192048, GO:0016605=GO_REF:0000024, GO:0045944=GO_REF:0000019, GO:0006508=GO_REF:0000037, GO:0001934=GO_REF:0000019, GO:0051028=GO_REF:0000037, GO:0008234=GO_REF:0000002, GO:0016055=GO_REF:0000037} Q9HC62 Sentrin-specific protease 2 protein 20130415 {GO:0005515=IPI, GO:0032091=IEA, GO:0031965=IEA, GO:0030111=NAS, GO:0016926=ISS, GO:0019904=IEA, GO:0016929=IDA, GO:0015031=IEA, GO:0009950=IEA, GO:0035562=IEA, GO:0007507=IEA, GO:0005737=IEA, GO:0005643=IDA, GO:0016605=ISS, GO:0045944=IEA, GO:0006508=IEA, GO:0001934=IEA, GO:0051028=IEA, GO:0008234=IEA, GO:0016055=IEA} Wnt receptor signaling pathway, dorsal/ventral axis specification, heart development, mRNA transport, negative regulation of chromatin binding, negative regulation of protein binding, positive regulation of protein phosphorylation, positive regulation of transcription from RNA polymerase II promoter, protein desumoylation, protein transport, proteolysis, regulation of Wnt receptor signaling pathway PML body, cytoplasm, nuclear membrane, nuclear pore SUMO-specific protease activity, cysteine-type peptidase activity, protein binding, protein domain specific binding Human UniProtKB:Q9Y6K9 SENP3 LIFEdb UniProtKB {GO:0005737=GO_REF:0000039, GO:0004843=GO_REF:0000019, GO:0071339=PMID:15960975, GO:0005730=GO_REF:0000054, GO:0006508=GO_REF:0000037, GO:0008234=GO_REF:0000002} Q9H4L4 Sentrin-specific protease 3 protein 20100607 {GO:0005737=IEA, GO:0004843=IEA, GO:0071339=IDA, GO:0005730=IDA, GO:0006508=IEA, GO:0008234=IEA} proteolysis MLL1 complex, cytoplasm, nucleolus cysteine-type peptidase activity, ubiquitin-specific protease activity Human SENP5 IntAct UniProtKB {GO:0005515=PMID:21217774, GO:0007049=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0006508=GO_REF:0000037, GO:0008234=GO_REF:0000037, GO:0051301=GO_REF:0000037} Q96HI0 Sentrin-specific protease 5 protein 20130415 {GO:0005515=IPI, GO:0007049=IEA, GO:0005730=IEA, GO:0006508=IEA, GO:0008234=IEA, GO:0051301=IEA} cell cycle, cell division, proteolysis nucleolus cysteine-type peptidase activity, protein binding Human UniProtKB:P03372 SENP6 HPA UniProtKB {GO:0005515=PMID:20212317, GO:0005737=GO_REF:0000052, GO:0016926=PMID:20212317, GO:0016925=GO_REF:0000041, GO:0005730=GO_REF:0000052, GO:0006508=GO_REF:0000037, GO:0070646=PMID:20212317, GO:0016929=PMID:20212317, GO:0005634=GO_REF:0000052, GO:0008234=GO_REF:0000002, GO:0090234=PMID:20212317, GO:0090169=PMID:20212317} Q9GZR1 Sentrin-specific protease 6 protein 20100326 {GO:0005515=IPI, GO:0005737=IDA, GO:0016926=IMP, GO:0016925=IEA, GO:0005730=IDA, GO:0006508=IEA, GO:0070646=IDA, GO:0016929=IMP, GO:0005634=IDA, GO:0008234=IEA, GO:0090234=IMP, GO:0090169=IMP} protein desumoylation, protein modification by small protein removal, protein sumoylation, proteolysis, regulation of kinetochore assembly, regulation of spindle assembly cytoplasm, nucleolus, nucleus SUMO-specific protease activity, cysteine-type peptidase activity, protein binding Human SENP7 LIFEdb UniProtKB {GO:0005622=GO_REF:0000054, GO:0006508=GO_REF:0000037, GO:0005634=GO_REF:0000054, GO:0008234=GO_REF:0000029} Q9BQF6 Sentrin-specific protease 7 protein 20100607 {GO:0005622=IDA, GO:0006508=IEA, GO:0005634=IDA, GO:0008234=NAS} proteolysis intracellular, nucleus cysteine-type peptidase activity Human SENP8 UniProtKB UniProtKB {GO:0006508=GO_REF:0000037, GO:0008234=GO_REF:0000037} Q96LD8 Sentrin-specific protease 8 protein 20130413 {GO:0006508=IEA, GO:0008234=IEA} proteolysis cysteine-type peptidase activity Human UniProtKB-KW:KW-0788 SEPHS1 InterPro UniProtKB {GO:0004756=GO_REF:0000002, GO:0005525=PMID:7665581, GO:0005524=GO_REF:0000002, GO:0006464=PMID:7665581} Q5T5U9 Selenophosphate synthetase 1 delta E8 variant protein 20130413 {GO:0004756=IEA, GO:0005525=TAS, GO:0005524=IEA, GO:0006464=TAS} cellular protein modification process ATP binding, GTP binding, selenide, water dikinase activity Human InterPro:IPR004536 SEPHS2 UniProtKB UniProtKB {GO:0004756=PMID:8986768, GO:0016260=PMID:8986768, GO:0005575=GO_REF:0000015, GO:0005524=GO_REF:0000037} Q99611 Selenide, water dikinase 2 protein 20010918 {GO:0004756=NAS, GO:0016260=NAS, GO:0005575=ND, GO:0005524=IEA} selenocysteine biosynthetic process cellular_component ATP binding, selenide, water dikinase activity Human SEPN1 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005509=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0005576=GO_REF:0000029} Q9NZV5 Selenoprotein N protein 20130415 {GO:0005515=IPI, GO:0003674=ND, GO:0008150=ND, GO:0005509=IEA, GO:0005789=IEA, GO:0005576=NAS} biological_process endoplasmic reticulum membrane, extracellular region calcium ion binding, molecular_function, protein binding Human UniProtKB:P16333 SEPP1 PINC UniProtKB {GO:0019953=GO_REF:0000019, GO:0001887=GO_REF:0000019, GO:0008430=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0005576=PMID:14718574, GO:0007626=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0006979=PMID:2037562, GO:0040007=GO_REF:0000019, GO:0005615=GO_REF:0000019} P49908 Selenoprotein P protein 20030904 {GO:0019953=IEA, GO:0001887=IEA, GO:0008430=IEA, GO:0007420=IEA, GO:0005576=NAS, GO:0007626=IEA, GO:0009791=IEA, GO:0006979=TAS, GO:0040007=IEA, GO:0005615=IEA} brain development, growth, locomotory behavior, post-embryonic development, response to oxidative stress, selenium compound metabolic process, sexual reproduction extracellular region, extracellular space selenium binding Human SEPSECS IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0005737=GO_REF:0000024, GO:0000049=GO_REF:0000024, GO:0001514=GO_REF:0000024, GO:0016785=GO_REF:0000002, GO:0030170=GO_REF:0000002, GO:0005634=GO_REF:0000024, GO:0097056=GO_REF:0000041, GO:0016740=GO_REF:0000002} Q9HD40 O-phosphoseryl-tRNA(Sec) selenium transferase protein 20130415 {GO:0005515=IPI, GO:0005737=ISS, GO:0000049=ISS, GO:0001514=ISS, GO:0016785=IEA, GO:0030170=IEA, GO:0005634=ISS, GO:0097056=IEA, GO:0016740=IEA} selenocysteine incorporation, selenocysteinyl-tRNA(Sec) biosynthetic process cytoplasm, nucleus protein binding, pyridoxal phosphate binding, tRNA binding, transferase activity, transferase activity, transferring selenium-containing groups Human UniProtKB:P04591:PRO_0000038593 SEPT1 UniProtKB UniProtKB {GO:0005515=PMID:17685441, GO:0031105=GO_REF:0000002, GO:0007049=GO_REF:0000037, GO:0005815=GO_REF:0000039, GO:0005525=GO_REF:0000037, GO:0051301=GO_REF:0000037} Q8WYJ6 Septin-1 protein 20081124 {GO:0005515=IPI, GO:0031105=IEA, GO:0007049=IEA, GO:0005815=IEA, GO:0005525=IEA, GO:0051301=IEA} cell cycle, cell division microtubule organizing center, septin complex GTP binding, protein binding Human UniProtKB:Q4V8G5 SEPT10 UniProtKB UniProtKB {GO:0031105=GO_REF:0000002, GO:0007049=GO_REF:0000037, GO:0005525=GO_REF:0000037, GO:0051301=GO_REF:0000037} Q9P0V9 Septin-10 protein 20130413 {GO:0031105=IEA, GO:0007049=IEA, GO:0005525=IEA, GO:0051301=IEA} cell cycle, cell division septin complex GTP binding Human UniProtKB-KW:KW-0132 SEPT11 HPA UniProtKB {GO:0005515=PMID:16767699, GO:0031105=GO_REF:0000002, GO:0030424=GO_REF:0000039, GO:0001725=PMID:15485874, GO:0005737=GO_REF:0000052, GO:0007049=GO_REF:0000037, GO:0030054=GO_REF:0000037, GO:0043197=GO_REF:0000039, GO:0045202=GO_REF:0000039, GO:0005525=GO_REF:0000037, GO:0051291=PMID:15485874, GO:0051301=GO_REF:0000037} Q9NVA2 Septin-11 protein 20080205 {GO:0005515=IPI, GO:0031105=IEA, GO:0030424=IEA, GO:0001725=IDA, GO:0005737=IDA, GO:0007049=IEA, GO:0030054=IEA, GO:0043197=IEA, GO:0045202=IEA, GO:0005525=IEA, GO:0051291=IDA, GO:0051301=IEA} cell cycle, cell division, protein heterooligomerization axon, cell junction, cytoplasm, dendritic spine, septin complex, stress fiber, synapse GTP binding, protein binding Human SEPT12 HPA UniProtKB {GO:0031105=GO_REF:0000024, GO:0005515=PMID:18047794, GO:0001725=GO_REF:0000024, GO:0048471=PMID:18047794, GO:0097227=PMID:22275165, GO:0005819=PMID:18047794, GO:0030496=PMID:18047794, GO:0005525=PMID:18443421, GO:0032154=GO_REF:0000024, GO:0042803=PMID:18443421, GO:0007049=GO_REF:0000037, GO:0015630=GO_REF:0000052, GO:0019003=GO_REF:0000024, GO:0035091=GO_REF:0000024, GO:0051301=GO_REF:0000037} Q8IYM1 Septin-12 protein 20111111 {GO:0031105=ISS, GO:0005515=IPI, GO:0001725=ISS, GO:0048471=IDA, GO:0097227=IDA, GO:0005819=IDA, GO:0030496=IDA, GO:0005525=IDA, GO:0032154=ISS, GO:0042803=IPI, GO:0007049=IEA, GO:0015630=IDA, GO:0019003=ISS, GO:0035091=ISS, GO:0051301=IEA} cell cycle, cell division cleavage furrow, microtubule cytoskeleton, midbody, perinuclear region of cytoplasm, septin complex, sperm annulus, spindle, stress fiber GDP binding, GTP binding, phosphatidylinositol binding, protein binding, protein homodimerization activity Human SEPT14 IntAct UniProtKB {GO:0005515=PMID:17922164, GO:0031105=GO_REF:0000002, GO:0007049=GO_REF:0000037, GO:0005525=GO_REF:0000037, GO:0051301=GO_REF:0000037} Q6ZU15 Septin-14 protein 20130415 {GO:0005515=IPI, GO:0031105=IEA, GO:0007049=IEA, GO:0005525=IEA, GO:0051301=IEA} cell cycle, cell division septin complex GTP binding, protein binding Human UniProtKB:Q9UHD8-1 SEPT2 HPA UniProtKB {GO:0005515=PMID:17803907, GO:0031105=GO_REF:0000002, GO:0048471=GO_REF:0000019, GO:0060170=GO_REF:0000024, GO:0045202=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0015629=GO_REF:0000052, GO:0032154=GO_REF:0000039, GO:0031175=GO_REF:0000019, GO:0007224=GO_REF:0000024, GO:0032880=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0000145=GO_REF:0000019, GO:0030234=GO_REF:0000019, GO:0005938=GO_REF:0000024, GO:0009986=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005819=GO_REF:0000039, GO:0030496=GO_REF:0000039, GO:0002036=GO_REF:0000019, GO:0005525=GO_REF:0000037, GO:0042384=GO_REF:0000024, GO:0032947=GO_REF:0000019, GO:0007049=GO_REF:0000002, GO:0007067=GO_REF:0000037, GO:0000777=GO_REF:0000039, GO:0051301=GO_REF:0000037} Q15019 Septin-2 protein 20120912 {GO:0005515=IPI, GO:0031105=IEA, GO:0048471=IEA, GO:0060170=ISS, GO:0045202=IEA, GO:0005634=IDA, GO:0015629=IDA, GO:0032154=IEA, GO:0031175=IEA, GO:0007224=ISS, GO:0032880=IEA, GO:0005737=IDA, GO:0000145=IEA, GO:0030234=IEA, GO:0005938=ISS, GO:0009986=IEA, GO:0005730=IDA, GO:0005819=IEA, GO:0030496=IEA, GO:0002036=IEA, GO:0005525=IEA, GO:0042384=ISS, GO:0032947=IEA, GO:0007049=IEA, GO:0007067=IEA, GO:0000777=IEA, GO:0051301=IEA} cell cycle, cell division, cilium assembly, mitosis, neuron projection development, regulation of L-glutamate transport, regulation of protein localization, smoothened signaling pathway actin cytoskeleton, cell cortex, cell surface, cilium membrane, cleavage furrow, condensed chromosome kinetochore, cytoplasm, exocyst, midbody, nucleolus, nucleus, perinuclear region of cytoplasm, septin complex, spindle, synapse GTP binding, enzyme regulator activity, protein binding, protein complex scaffold Human SEPT3 UniProtKB UniProtKB {GO:0031105=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0000910=GO_REF:0000029, GO:0007049=GO_REF:0000037, GO:0030054=GO_REF:0000037, GO:0045202=GO_REF:0000039, GO:0005525=GO_REF:0000037} Q9UH03 Neuronal-specific septin-3 protein 20061026 {GO:0031105=IEA, GO:0003674=ND, GO:0000910=NAS, GO:0007049=IEA, GO:0030054=IEA, GO:0045202=IEA, GO:0005525=IEA} cell cycle, cytokinesis cell junction, septin complex, synapse GTP binding, molecular_function Human SEPT4 GOC UniProtKB {GO:0031105=GO_REF:0000002, GO:0005515=PMID:17685441, GO:0043065=PMID:21185211, GO:0005730=GO_REF:0000052, GO:0003924=PMID:9889007, GO:0006915=PMID:11146656, GO:0005634=GO_REF:0000052, GO:0042981=PMID:11146656, GO:0042995=GO_REF:0000019, GO:0005525=GO_REF:0000037, GO:0030382=GO_REF:0000019, GO:0006184=PMID:9889007, GO:0005739=PMID:11146656, GO:0000910=PMID:9889007, GO:0007049=GO_REF:0000037, GO:0005198=PMID:9889007, GO:0007420=GO_REF:0000019, GO:0031398=PMID:21185211, GO:0005856=GO_REF:0000039, GO:0048240=GO_REF:0000019} O43236 Septin-4 protein 20130413 {GO:0031105=IEA, GO:0005515=IPI, GO:0043065=IDA, GO:0005730=IDA, GO:0003924=TAS, GO:0006915=NAS, GO:0005634=IDA, GO:0042981=NAS, GO:0042995=IEA, GO:0005525=IEA, GO:0030382=IEA, GO:0006184=TAS, GO:0005739=NAS, GO:0000910=TAS, GO:0007049=IEA, GO:0005198=TAS, GO:0007420=IEA, GO:0031398=IDA, GO:0005856=IEA, GO:0048240=IEA} GTP catabolic process, apoptotic process, brain development, cell cycle, cytokinesis, positive regulation of apoptotic process, positive regulation of protein ubiquitination, regulation of apoptotic process, sperm capacitation, sperm mitochondrion organization cell projection, cytoskeleton, mitochondrion, nucleolus, nucleus, septin complex GTP binding, GTPase activity, protein binding, structural molecule activity Human SEPT5 GOC UniProtKB {GO:0031105=GO_REF:0000002, GO:0005515=PMID:16767699, GO:0016080=PMID:10321247, GO:0005886=PMID:10321247, GO:0003924=PMID:9385360, GO:0005525=GO_REF:0000037, GO:0008021=PMID:10321247, GO:0006184=PMID:9385360, GO:0000910=PMID:9611266, GO:0007049=GO_REF:0000037, GO:0005198=PMID:9611266, GO:0043195=GO_REF:0000019, GO:0017157=PMID:10321247, GO:0005938=GO_REF:0000019} Q99719 Septin-5 protein 20130413 {GO:0031105=IEA, GO:0005515=IPI, GO:0016080=TAS, GO:0005886=IDA, GO:0003924=TAS, GO:0005525=IEA, GO:0008021=IDA, GO:0006184=TAS, GO:0000910=TAS, GO:0007049=IEA, GO:0005198=TAS, GO:0043195=IEA, GO:0017157=IMP, GO:0005938=IEA} GTP catabolic process, cell cycle, cytokinesis, regulation of exocytosis, synaptic vesicle targeting cell cortex, plasma membrane, septin complex, synaptic vesicle, terminal bouton GTP binding, GTPase activity, protein binding, structural molecule activity Human SEPT6 HPA UniProtKB {GO:0031105=GO_REF:0000002, GO:0005515=PMID:18047794, GO:0005819=GO_REF:0000039, GO:0030496=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0005525=PMID:11809673, GO:0032154=GO_REF:0000039, GO:0008021=GO_REF:0000019, GO:0000910=PMID:11809673, GO:0007049=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0019048=GO_REF:0000037, GO:0000777=GO_REF:0000039, GO:0043679=GO_REF:0000019} Q14141 Septin-6 protein 20080205 {GO:0031105=IEA, GO:0005515=IPI, GO:0005819=IEA, GO:0030496=IEA, GO:0005575=ND, GO:0005525=TAS, GO:0032154=IEA, GO:0008021=IEA, GO:0000910=TAS, GO:0007049=IEA, GO:0005737=IDA, GO:0019048=IEA, GO:0000777=IEA, GO:0043679=IEA} cell cycle, cytokinesis, virus-host interaction axon terminus, cellular_component, cleavage furrow, condensed chromosome kinetochore, cytoplasm, midbody, septin complex, spindle, synaptic vesicle GTP binding, protein binding Human SEPT7 HPA UniProtKB {GO:0031105=GO_REF:0000002, GO:0005515=PMID:17685441, GO:0005886=GO_REF:0000052, GO:0045202=GO_REF:0000019, GO:0005634=PMID:15485874, GO:0015629=GO_REF:0000052, GO:0035085=GO_REF:0000024, GO:0032154=GO_REF:0000039, GO:0051291=PMID:15485874, GO:0000910=PMID:8037772, GO:0005737=GO_REF:0000052, GO:0016324=GO_REF:0000024, GO:0015630=GO_REF:0000052, GO:0043679=GO_REF:0000019, GO:0001725=PMID:15485874, GO:0005819=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0030496=GO_REF:0000039, GO:0005525=GO_REF:0000037, GO:0007049=GO_REF:0000002, GO:0007067=GO_REF:0000037, GO:0016476=GO_REF:0000024, GO:0005198=PMID:8037772, GO:0060271=GO_REF:0000024, GO:0000777=GO_REF:0000039} Q16181 Septin-7 protein 20110516 {GO:0031105=IEA, GO:0005515=IPI, GO:0005886=IDA, GO:0045202=IEA, GO:0005634=IDA, GO:0015629=IDA, GO:0035085=ISS, GO:0032154=IEA, GO:0051291=IDA, GO:0000910=TAS, GO:0005737=IDA, GO:0016324=ISS, GO:0015630=IDA, GO:0043679=IEA, GO:0001725=IDA, GO:0005819=IEA, GO:0005730=IDA, GO:0030496=IEA, GO:0005525=IEA, GO:0007049=IEA, GO:0007067=IEA, GO:0016476=ISS, GO:0005198=TAS, GO:0060271=ISS, GO:0000777=IEA} cell cycle, cilium morphogenesis, cytokinesis, mitosis, protein heterooligomerization, regulation of embryonic cell shape actin cytoskeleton, apical plasma membrane, axon terminus, cilium axoneme, cleavage furrow, condensed chromosome kinetochore, cytoplasm, microtubule cytoskeleton, midbody, nucleolus, nucleus, plasma membrane, septin complex, spindle, stress fiber, synapse GTP binding, protein binding, structural molecule activity Human SEPT8 HPA UniProtKB {GO:0005515=PMID:17685441, GO:0031105=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0007049=GO_REF:0000002, GO:0005525=GO_REF:0000037} Q92599 Septin-8 protein 20080205 {GO:0005515=IPI, GO:0031105=IEA, GO:0005737=IDA, GO:0007049=IEA, GO:0005525=IEA} cell cycle cytoplasm, septin complex GTP binding, protein binding Human SEPT9 GOC UniProtKB {GO:0031105=GO_REF:0000002, GO:0005515=PMID:16007136, GO:0001725=PMID:15485874, GO:0048471=PMID:15485874, GO:0005874=PMID:15485874, GO:0003924=PMID:10339604, GO:0005525=GO_REF:0000037, GO:0015629=GO_REF:0000052, GO:0051291=PMID:15485874, GO:0006184=PMID:10339604, GO:0007049=GO_REF:0000037, GO:0005737=PMID:10339604, GO:0051301=GO_REF:0000037} Q9UHD8 Septin-9 protein 20130413 {GO:0031105=IEA, GO:0005515=IPI, GO:0001725=IDA, GO:0048471=IDA, GO:0005874=IDA, GO:0003924=TAS, GO:0005525=IEA, GO:0015629=IDA, GO:0051291=IDA, GO:0006184=TAS, GO:0007049=IEA, GO:0005737=TAS, GO:0051301=IEA} GTP catabolic process, cell cycle, cell division, protein heterooligomerization actin cytoskeleton, cytoplasm, microtubule, perinuclear region of cytoplasm, septin complex, stress fiber GTP binding, GTPase activity, protein binding Human SERAC1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0031012=GO_REF:0000019, GO:0005783=GO_REF:0000039, GO:0030198=GO_REF:0000019, GO:0016788=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0008654=GO_REF:0000037, GO:0006886=GO_REF:0000002, GO:0006505=GO_REF:0000002} Q96JX3 Protein SERAC1 protein 20130413 {GO:0005739=IEA, GO:0031012=IEA, GO:0005783=IEA, GO:0030198=IEA, GO:0016788=IEA, GO:0016021=IEA, GO:0008654=IEA, GO:0006886=IEA, GO:0006505=IEA} GPI anchor metabolic process, extracellular matrix organization, intracellular protein transport, phospholipid biosynthetic process endoplasmic reticulum, extracellular matrix, integral to membrane, mitochondrion hydrolase activity, acting on ester bonds Human UniProtKB-SubCell:SL-0095 SERBP1 HPA UniProtKB {GO:0005515=PMID:12505151, GO:0043488=PMID:11001948, GO:0005737=GO_REF:0000052, GO:0048471=GO_REF:0000039, GO:0005886=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0003730=PMID:11001948} Q8NC51 Plasminogen activator inhibitor 1 RNA-binding protein protein 20111111 {GO:0005515=IPI, GO:0043488=NAS, GO:0005737=IDA, GO:0048471=IEA, GO:0005886=IEA, GO:0005634=IEA, GO:0003730=IDA} regulation of mRNA stability cytoplasm, nucleus, perinuclear region of cytoplasm, plasma membrane mRNA 3'-UTR binding, protein binding Human SERF1A PINC UniProtKB {GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0007399=PMID:9731538} O75920 Small EDRK-rich factor 1 protein 20050308 {GO:0003674=ND, GO:0005575=ND, GO:0007399=TAS} nervous system development cellular_component molecular_function Human SERF2 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005634=GO_REF:0000024, GO:0005829=GO_REF:0000024} P84101 Small EDRK-rich factor 2 protein 20110418 {GO:0008150=ND, GO:0003674=ND, GO:0005634=ISS, GO:0005829=ISS} biological_process cytosol, nucleus molecular_function Human SERGEF HPA UniProtKB {GO:0005515=PMID:14980502, GO:0007165=PMID:10571079, GO:0005737=PMID:10571079, GO:0005730=GO_REF:0000052, GO:0050709=PMID:12459492, GO:0005634=GO_REF:0000052, GO:0045111=GO_REF:0000052, GO:0005087=PMID:10571079} Q9UGK8 Secretion-regulating guanine nucleotide exchange factor protein 20110516 {GO:0005515=IPI, GO:0007165=TAS, GO:0005737=IDA, GO:0005730=IDA, GO:0050709=IDA, GO:0005634=IDA, GO:0045111=IDA, GO:0005087=TAS} negative regulation of protein secretion, signal transduction cytoplasm, intermediate filament cytoskeleton, nucleolus, nucleus Ran guanyl-nucleotide exchange factor activity, protein binding Human SERHL2 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0048471=GO_REF:0000039, GO:0016787=GO_REF:0000037, GO:0016023=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0005777=GO_REF:0000039} Q9H4I8 Serine hydrolase-like protein 2 protein 20120517 {GO:0005739=IEA, GO:0003674=ND, GO:0008150=ND, GO:0048471=IEA, GO:0016787=IEA, GO:0016023=IEA, GO:0005575=ND, GO:0005777=IEA} biological_process cellular_component, cytoplasmic membrane-bounded vesicle, mitochondrion, perinuclear region of cytoplasm, peroxisome hydrolase activity, molecular_function Human SERINC1 IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0006665=GO_REF:0000024, GO:0015194=GO_REF:0000024, GO:0005886=GO_REF:0000024, GO:0015825=GO_REF:0000024, GO:0005789=GO_REF:0000024, GO:0051347=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0008654=GO_REF:0000037, GO:0006658=GO_REF:0000024} Q9NRX5 Serine incorporator 1 protein 20130415 {GO:0005515=IPI, GO:0006665=ISS, GO:0015194=ISS, GO:0005886=ISS, GO:0015825=ISS, GO:0005789=ISS, GO:0051347=ISS, GO:0016021=IEA, GO:0008654=IEA, GO:0006658=ISS} L-serine transport, phosphatidylserine metabolic process, phospholipid biosynthetic process, positive regulation of transferase activity, sphingolipid metabolic process endoplasmic reticulum membrane, integral to membrane, plasma membrane L-serine transmembrane transporter activity, protein binding Human UniProtKB:Q06710 SERINC3 ENSEMBL UniProtKB {GO:0005794=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0006917=GO_REF:0000019} Q5H936 Serine incorporator 3 protein 20130413 {GO:0005794=IEA, GO:0005886=IEA, GO:0016021=IEA, GO:0006917=IEA} induction of apoptosis Golgi apparatus, integral to membrane, plasma membrane Human Ensembl:ENSMUSP00000017851 SERP1 Reactome UniProtKB {GO:0007009=PMID:10601334, GO:0060124=GO_REF:0000019, GO:0005881=PMID:23264731, GO:0046622=GO_REF:0000019, GO:0005783=PMID:10601334, GO:0006950=PMID:10601334, GO:0010259=GO_REF:0000019, GO:0045727=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0009791=GO_REF:0000019, GO:0030968=Reactome:REACT_18356, GO:0048644=GO_REF:0000019, GO:0001501=GO_REF:0000019, GO:0005789=Reactome:REACT_115764, GO:0005840=PMID:10601334, GO:0006006=GO_REF:0000019, GO:0006486=GO_REF:0000019, GO:0032024=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0006464=PMID:10601334} Q9Y6X1 Stress-associated endoplasmic reticulum protein 1 protein 20130301 {GO:0007009=TAS, GO:0060124=IEA, GO:0005881=IDA, GO:0046622=IEA, GO:0005783=TAS, GO:0006950=TAS, GO:0010259=IEA, GO:0045727=IEA, GO:0015031=IEA, GO:0009791=IEA, GO:0030968=TAS, GO:0048644=IEA, GO:0001501=IEA, GO:0005789=TAS, GO:0005840=TAS, GO:0006006=IEA, GO:0006486=IEA, GO:0032024=IEA, GO:0016021=IEA, GO:0006987=TAS, GO:0044267=TAS, GO:0006464=TAS} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, cellular protein modification process, endoplasmic reticulum unfolded protein response, glucose metabolic process, multicellular organismal aging, muscle organ morphogenesis, plasma membrane organization, positive regulation of growth hormone secretion, positive regulation of insulin secretion, positive regulation of organ growth, positive regulation of translation, post-embryonic development, protein glycosylation, protein transport, response to stress, skeletal system development cytoplasmic microtubule, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, ribosome Human SERP2 UniProtKB UniProtKB {GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0015031=GO_REF:0000037} Q8N6R1 Stress-associated endoplasmic reticulum protein 2 protein 20130413 {GO:0005789=IEA, GO:0016021=IEA, GO:0015031=IEA} protein transport endoplasmic reticulum membrane, integral to membrane Human UniProtKB-SubCell:SL-0097 SERPINA1 BHF-UCL UniProtKB {GO:0005515=PMID:16321984, GO:0001666=GO_REF:0000019, GO:0010288=GO_REF:0000019, GO:0033986=GO_REF:0000019, GO:0004866=GO_REF:0000019, GO:0004867=PMID:15795238, GO:0005578=GO_REF:0000039, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_21351, GO:0006953=GO_REF:0000037, GO:0002020=PMID:15853774, GO:0005615=PMID:6980881, GO:0030162=GO_REF:0000033, GO:0010951=GO_REF:0000033, GO:0006954=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0034014=GO_REF:0000019, GO:0002576=Reactome:REACT_318, GO:0032496=GO_REF:0000019, GO:0031093=Reactome:REACT_21351, GO:0034097=GO_REF:0000019, GO:0032355=GO_REF:0000019, GO:0046687=GO_REF:0000019} P01009 Alpha-1-antitrypsin protein 20111202 {GO:0005515=IPI, GO:0001666=IEA, GO:0010288=IEA, GO:0033986=IEA, GO:0004866=IEA, GO:0004867=IDA, GO:0005578=IEA, GO:0030168=TAS, GO:0005576=TAS, GO:0006953=IEA, GO:0002020=IPI, GO:0005615=IDA, GO:0030162=IBA, GO:0010951=IBA, GO:0006954=IEA, GO:0007596=TAS, GO:0034014=IEA, GO:0002576=TAS, GO:0032496=IEA, GO:0031093=TAS, GO:0034097=IEA, GO:0032355=IEA, GO:0046687=IEA} acute-phase response, blood coagulation, inflammatory response, negative regulation of endopeptidase activity, platelet activation, platelet degranulation, regulation of proteolysis, response to chromate, response to cytokine stimulus, response to estradiol stimulus, response to hypoxia, response to lead ion, response to lipopolysaccharide, response to methanol, response to triglyceride extracellular region, extracellular space, platelet alpha granule lumen, proteinaceous extracellular matrix endopeptidase inhibitor activity, protease binding, protein binding, serine-type endopeptidase inhibitor activity Human SERPINA10 UniProtKB UniProtKB {GO:0030162=GO_REF:0000033, GO:0010951=GO_REF:0000033, GO:0060046=PMID:11751269, GO:0007596=GO_REF:0000037, GO:0004867=GO_REF:0000033, GO:0005576=GO_REF:0000039, GO:0008201=GO_REF:0000037} Q9UK55 Protein Z-dependent protease inhibitor protein 20110215 {GO:0030162=IBA, GO:0010951=IBA, GO:0060046=IDA, GO:0007596=IEA, GO:0004867=IBA, GO:0005576=IEA, GO:0008201=IEA} blood coagulation, negative regulation of endopeptidase activity, regulation of acrosome reaction, regulation of proteolysis extracellular region heparin binding, serine-type endopeptidase inhibitor activity NOT Human SERPINA12 RefGenome UniProtKB {GO:0030162=GO_REF:0000033, GO:0010951=GO_REF:0000033, GO:0004867=GO_REF:0000033, GO:0005576=GO_REF:0000039} Q8IW75 Serpin A12 protein 20110204 {GO:0030162=IBA, GO:0010951=IBA, GO:0004867=IBA, GO:0005576=IEA} negative regulation of endopeptidase activity, regulation of proteolysis extracellular region serine-type endopeptidase inhibitor activity Human PANTHER:PTN000156122 SERPINA3 IntAct UniProtKB {GO:0005622=PMID:9880565, GO:0030162=GO_REF:0000033, GO:0010951=GO_REF:0000033, GO:0005515=PMID:14668352, GO:0006954=PMID:12475184, GO:0030277=PMID:8647626, GO:0004867=PMID:2404007, GO:0005634=PMID:14668352, GO:0005576=PMID:14718574, GO:0006953=GO_REF:0000037, GO:0003677=PMID:14668352, GO:0019216=PMID:11835318} P01011 Alpha-1-antichymotrypsin protein 20130415 {GO:0005622=NAS, GO:0030162=IBA, GO:0010951=IBA, GO:0005515=IPI, GO:0006954=NAS, GO:0030277=NAS, GO:0004867=TAS, GO:0005634=TAS, GO:0005576=NAS, GO:0006953=IEA, GO:0003677=TAS, GO:0019216=NAS} acute-phase response, inflammatory response, maintenance of gastrointestinal epithelium, negative regulation of endopeptidase activity, regulation of lipid metabolic process, regulation of proteolysis extracellular region, intracellular, nucleus DNA binding, protein binding, serine-type endopeptidase inhibitor activity Human UniProtKB:Q96KC8 SERPINA4 RefGenome UniProtKB {GO:0030162=GO_REF:0000033, GO:0010951=GO_REF:0000033, GO:0004867=GO_REF:0000033} P29622 Kallistatin protein 20110204 {GO:0030162=IBA, GO:0010951=IBA, GO:0004867=IBA} negative regulation of endopeptidase activity, regulation of proteolysis serine-type endopeptidase inhibitor activity Human PANTHER:PTN000156122 SERPINA5 UniProtKB UniProtKB {GO:0097181=PMID:6323392, GO:0097182=PMID:6323392, GO:0004867=PMID:15853774, GO:0097183=PMID:2844223, GO:0007283=GO_REF:0000024, GO:0005539=PMID:8796266, GO:0032190=PMID:7521127, GO:0002020=PMID:2844223, GO:0005615=PMID:10340997, GO:0030162=GO_REF:0000033, GO:0036024=PMID:15853774, GO:0036025=PMID:15328353, GO:0036026=PMID:10340997, GO:0031091=PMID:9556620, GO:0031094=PMID:9556620, GO:0002080=PMID:9510955, GO:0008201=PMID:11120760, GO:0070062=PMID:21557262, GO:0031210=PMID:9556620, GO:0005576=PMID:11120760, GO:0036029=PMID:1725227, GO:0036028=PMID:6323392, GO:0045861=GO_REF:0000019, GO:0036027=PMID:8536714, GO:0010951=GO_REF:0000033, GO:0043234=PMID:7521127, GO:0016020=PMID:7521127, GO:0007342=PMID:9510955, GO:0036030=PMID:8536714, GO:0001972=PMID:11722589, GO:0006869=GO_REF:0000037, GO:0009897=PMID:9556620} P05154 Plasma serine protease inhibitor protein 20111010 {GO:0097181=IDA, GO:0097182=IDA, GO:0004867=IDA, GO:0097183=IDA, GO:0007283=ISS, GO:0005539=TAS, GO:0032190=IPI, GO:0002020=IPI, GO:0005615=IDA, GO:0030162=IBA, GO:0036024=IDA, GO:0036025=IDA, GO:0036026=IDA, GO:0031091=IDA, GO:0031094=IDA, GO:0002080=IDA, GO:0008201=TAS, GO:0070062=IDA, GO:0031210=IDA, GO:0005576=TAS, GO:0036029=IDA, GO:0036028=IDA, GO:0045861=IEA, GO:0036027=IDA, GO:0010951=IBA, GO:0043234=IDA, GO:0016020=IDA, GO:0007342=NAS, GO:0036030=IDA, GO:0001972=IDA, GO:0006869=IEA, GO:0009897=IDA} fusion of sperm to egg plasma membrane, lipid transport, negative regulation of endopeptidase activity, negative regulation of proteolysis, regulation of proteolysis, spermatogenesis acrosomal membrane, external side of plasma membrane, extracellular region, extracellular space, extracellular vesicular exosome, membrane, platelet alpha granule, platelet dense tubular network, protein C inhibitor-KLK3 complex, protein C inhibitor-PLAT complex, protein C inhibitor-PLAU complex, protein C inhibitor-TMPRSS11E complex, protein C inhibitor-TMPRSS7 complex, protein C inhibitor-coagulation factor V complex, protein C inhibitor-coagulation factor XI complex, protein C inhibitor-coagulation factor Xa complex, protein C inhibitor-plasma kallikrein complex, protein C inhibitor-thrombin complex, protein complex acrosin binding, glycosaminoglycan binding, heparin binding, phosphatidylcholine binding, protease binding, retinoic acid binding, serine-type endopeptidase inhibitor activity Human UniProtKB:P12259 SERPINA7 RefGenome UniProtKB {GO:0051412=GO_REF:0000019, GO:0004867=GO_REF:0000033, GO:0033189=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0042562=GO_REF:0000019, GO:0043434=GO_REF:0000019, GO:0005576=GO_REF:0000033, GO:0009791=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0010951=GO_REF:0000033, GO:0030162=GO_REF:0000033, GO:0034695=GO_REF:0000019} P05543 Thyroxine-binding globulin protein 20110204 {GO:0051412=IEA, GO:0004867=IBA, GO:0033189=IEA, GO:0042493=IEA, GO:0007568=IEA, GO:0042562=IEA, GO:0043434=IEA, GO:0005576=IBA, GO:0009791=IEA, GO:0005615=IEA, GO:0010951=IBA, GO:0030162=IBA, GO:0034695=IEA} aging, negative regulation of endopeptidase activity, post-embryonic development, regulation of proteolysis, response to corticosterone stimulus, response to drug, response to peptide hormone stimulus, response to prostaglandin E stimulus, response to vitamin A extracellular region, extracellular space hormone binding, serine-type endopeptidase inhibitor activity Human PANTHER:PTN000156122 SERPINB1 RefGenome UniProtKB {GO:0030162=GO_REF:0000033, GO:0010951=GO_REF:0000033, GO:0005737=GO_REF:0000029, GO:0004867=GO_REF:0000033} P30740 Leukocyte elastase inhibitor protein 20110204 {GO:0030162=IBA, GO:0010951=IBA, GO:0005737=NAS, GO:0004867=IBA} negative regulation of endopeptidase activity, regulation of proteolysis cytoplasm serine-type endopeptidase inhibitor activity Human PANTHER:PTN000156122 SERPINB12 UniProtKB UniProtKB {GO:0030162=GO_REF:0000033, GO:0010951=GO_REF:0000033, GO:0005737=PMID:11604408, GO:0042177=PMID:11604408, GO:0004867=PMID:11604408, GO:0019899=PMID:11604408} Q96P63 Serpin B12 protein 20030403 {GO:0030162=IBA, GO:0010951=IBA, GO:0005737=NAS, GO:0042177=NAS, GO:0004867=IMP, GO:0019899=NAS} negative regulation of endopeptidase activity, negative regulation of protein catabolic process, regulation of proteolysis cytoplasm enzyme binding, serine-type endopeptidase inhibitor activity Human SERPINB13 PINC UniProtKB {GO:0030162=PMID:10512713, GO:0010951=GO_REF:0000033, GO:0005737=GO_REF:0000039, GO:0004867=PMID:10512713, GO:0005576=GO_REF:0000033, GO:0009411=PMID:9297979} Q9UIV8 Serpin B13 protein 20030904 {GO:0030162=NAS, GO:0010951=IBA, GO:0005737=IEA, GO:0004867=NAS, GO:0005576=IBA, GO:0009411=TAS} negative regulation of endopeptidase activity, regulation of proteolysis, response to UV cytoplasm, extracellular region serine-type endopeptidase inhibitor activity Human SERPINB2 Reactome UniProtKB {GO:0030162=GO_REF:0000033, GO:0010951=GO_REF:0000033, GO:0043066=PMID:7499264, GO:0005737=GO_REF:0000039, GO:0005886=Reactome:REACT_142, GO:0007596=Reactome:REACT_604, GO:0004867=GO_REF:0000033, GO:0042060=GO_REF:0000019, GO:0005576=Reactome:REACT_142, GO:0042730=Reactome:REACT_641, GO:0005615=GO_REF:0000039} P05120 Plasminogen activator inhibitor 2 protein 20130213 {GO:0030162=IBA, GO:0010951=IBA, GO:0043066=TAS, GO:0005737=IEA, GO:0005886=TAS, GO:0007596=TAS, GO:0004867=IBA, GO:0042060=IEA, GO:0005576=TAS, GO:0042730=TAS, GO:0005615=IEA} blood coagulation, fibrinolysis, negative regulation of apoptotic process, negative regulation of endopeptidase activity, regulation of proteolysis, wound healing cytoplasm, extracellular region, extracellular space, plasma membrane serine-type endopeptidase inhibitor activity Human SERPINB3 GOC UniProtKB {GO:0030162=GO_REF:0000033, GO:0010951=GO_REF:0000033, GO:0005737=GO_REF:0000039, GO:0001618=PMID:12975381, GO:0004867=GO_REF:0000033, GO:0005576=GO_REF:0000033, GO:0009615=PMID:12975381, GO:0043086=PMID:10956412, GO:0045861=PMID:12975381} P29508 Serpin B3 protein 20130413 {GO:0030162=IBA, GO:0010951=IBA, GO:0005737=IEA, GO:0001618=IDA, GO:0004867=IBA, GO:0005576=IBA, GO:0009615=IDA, GO:0043086=IDA, GO:0045861=IDA} negative regulation of catalytic activity, negative regulation of endopeptidase activity, negative regulation of proteolysis, regulation of proteolysis, response to virus cytoplasm, extracellular region serine-type endopeptidase inhibitor activity, viral receptor activity Human SERPINB4 RefGenome UniProtKB {GO:0010951=GO_REF:0000033, GO:0030162=GO_REF:0000033, GO:0006955=GO_REF:0000029, GO:0005737=GO_REF:0000029, GO:0004867=GO_REF:0000033, GO:0005576=GO_REF:0000033} P48594 Serpin B4 protein 20110204 {GO:0010951=IBA, GO:0030162=IBA, GO:0006955=NAS, GO:0005737=NAS, GO:0004867=IBA, GO:0005576=IBA} immune response, negative regulation of endopeptidase activity, regulation of proteolysis cytoplasm, extracellular region serine-type endopeptidase inhibitor activity Human PANTHER:PTN000156122 SERPINB5 HPA UniProtKB {GO:0005515=PMID:16049006, GO:0030162=GO_REF:0000033, GO:0010951=GO_REF:0000033, GO:0050678=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0030198=GO_REF:0000019, GO:0004867=GO_REF:0000033, GO:0006928=PMID:8290962, GO:0060512=GO_REF:0000019, GO:0005615=GO_REF:0000039, GO:0002009=GO_REF:0000019} P36952 Serpin B5 protein 20101115 {GO:0005515=IPI, GO:0030162=IBA, GO:0010951=IBA, GO:0050678=IEA, GO:0005737=IDA, GO:0030198=IEA, GO:0004867=IBA, GO:0006928=TAS, GO:0060512=IEA, GO:0005615=IEA, GO:0002009=IEA} cellular component movement, extracellular matrix organization, morphogenesis of an epithelium, negative regulation of endopeptidase activity, prostate gland morphogenesis, regulation of epithelial cell proliferation, regulation of proteolysis cytoplasm, extracellular space protein binding, serine-type endopeptidase inhibitor activity Human SERPINB6 BHF-UCL UniProtKB {GO:0030162=GO_REF:0000033, GO:0010951=PMID:17761692, GO:0043234=PMID:17761692, GO:0005813=GO_REF:0000052, GO:0005737=PMID:17761692, GO:0004867=PMID:17761692, GO:0002020=PMID:17761692, GO:0005829=PMID:8415716} P35237 Serpin B6 protein 20110310 {GO:0030162=IBA, GO:0010951=IDA, GO:0043234=IDA, GO:0005813=IDA, GO:0005737=IDA, GO:0004867=IDA, GO:0002020=IPI, GO:0005829=TAS} negative regulation of endopeptidase activity, regulation of proteolysis centrosome, cytoplasm, cytosol, protein complex protease binding, serine-type endopeptidase inhibitor activity Human SERPINB8 UniProtKB UniProtKB {GO:0010951=PMID:8530382, GO:0005515=PMID:8530382, GO:0030162=GO_REF:0000033, GO:0004867=PMID:8530382, GO:0005829=PMID:8530382} P50452 Serpin B8 protein 20100312 {GO:0010951=IDA, GO:0005515=IPI, GO:0030162=IBA, GO:0004867=IDA, GO:0005829=IDA} negative regulation of endopeptidase activity, regulation of proteolysis cytosol protein binding, serine-type endopeptidase inhibitor activity Human SERPINB9 GOC UniProtKB {GO:0005515=PMID:17479112, GO:0030162=GO_REF:0000033, GO:0010951=GO_REF:0000033, GO:0002448=PMID:15739160, GO:0006955=PMID:16306080, GO:0043066=PMID:17479112, GO:0004867=PMID:8910377, GO:0071391=PMID:17237823, GO:0043154=PMID:17479112, GO:0002020=PMID:16267761, GO:0005615=PMID:16267761, GO:0043027=PMID:17479112} P50453 Serpin B9 protein 20130413 {GO:0005515=IPI, GO:0030162=IBA, GO:0010951=IBA, GO:0002448=IEP, GO:0006955=IDA, GO:0043066=IMP, GO:0004867=IDA, GO:0071391=IEP, GO:0043154=IMP, GO:0002020=IPI, GO:0005615=IDA, GO:0043027=IMP} cellular response to estrogen stimulus, immune response, mast cell mediated immunity, negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of endopeptidase activity, regulation of proteolysis extracellular space cysteine-type endopeptidase inhibitor activity involved in apoptotic process, protease binding, protein binding, serine-type endopeptidase inhibitor activity Human SERPINC1 BHF-UCL UniProtKB {GO:0030162=GO_REF:0000033, GO:0010951=GO_REF:0000033, GO:0005515=PMID:12878203, GO:0005886=Reactome:REACT_1822, GO:0007596=Reactome:REACT_2051, GO:0004867=GO_REF:0000033, GO:0007584=GO_REF:0000019, GO:0050728=GO_REF:0000019, GO:0005576=Reactome:REACT_1283, GO:0002020=PMID:15853774, GO:0005615=PMID:1695900, GO:0008201=GO_REF:0000019} P01008 Antithrombin-III protein 20100330 {GO:0030162=IBA, GO:0010951=IBA, GO:0005515=IPI, GO:0005886=TAS, GO:0007596=TAS, GO:0004867=IBA, GO:0007584=IEA, GO:0050728=IEA, GO:0005576=TAS, GO:0002020=IPI, GO:0005615=IDA, GO:0008201=IEA} blood coagulation, negative regulation of endopeptidase activity, negative regulation of inflammatory response, regulation of proteolysis, response to nutrient extracellular region, extracellular space, plasma membrane heparin binding, protease binding, protein binding, serine-type endopeptidase inhibitor activity Human SERPIND1 PINC UniProtKB {GO:0030162=GO_REF:0000033, GO:0010951=GO_REF:0000033, GO:0004866=PMID:2647747, GO:0006935=GO_REF:0000037, GO:0004867=GO_REF:0000033, GO:0007596=GO_REF:0000037, GO:0005576=PMID:14718574, GO:0008201=GO_REF:0000037} P05546 Heparin cofactor 2 protein 20030904 {GO:0030162=IBA, GO:0010951=IBA, GO:0004866=TAS, GO:0006935=IEA, GO:0004867=IBA, GO:0007596=IEA, GO:0005576=NAS, GO:0008201=IEA} blood coagulation, chemotaxis, negative regulation of endopeptidase activity, regulation of proteolysis extracellular region endopeptidase inhibitor activity, heparin binding, serine-type endopeptidase inhibitor activity Human SERPINE1 BHF-UCL UniProtKB {GO:0033629=PMID:8837777, GO:0005515=PMID:16272158, GO:0010467=Reactome:REACT_71, GO:0010469=PMID:8837777, GO:0035491=PMID:19916862, GO:0006367=Reactome:REACT_12627, GO:0005886=Reactome:REACT_863, GO:0004867=PMID:8508955, GO:2000098=PMID:8837777, GO:0002020=PMID:8508955, GO:0005615=PMID:18835034, GO:0014912=PMID:8837777, GO:0032757=PMID:19916862, GO:0061044=PMID:9386191, GO:0061045=PMID:8837777, GO:0042127=GO_REF:0000019, GO:0045944=Reactome:REACT_120734, GO:0007179=Reactome:REACT_6844, GO:0031093=Reactome:REACT_21351, GO:0030336=PMID:10902815, GO:0043066=PMID:18835034, GO:0005102=PMID:8626514, GO:0051918=PMID:2503541, GO:0030168=Reactome:REACT_798, GO:0005576=PMID:9386191, GO:0070887=PMID:19916862, GO:0001525=PMID:11866539, GO:0006351=Reactome:REACT_121061, GO:0045766=PMID:18835034, GO:0031012=PMID:1632457, GO:0010951=PMID:1695900, GO:0050829=PMID:17032919, GO:0071222=PMID:19916862, GO:0030194=PMID:9207454, GO:0007596=Reactome:REACT_604, GO:0030195=PMID:1695900, GO:0048260=PMID:8626514, GO:0050729=PMID:17032919, GO:0002576=Reactome:REACT_318, GO:0001300=PMID:18974388, GO:0010757=PMID:8508955, GO:0090026=PMID:19916862, GO:0042730=Reactome:REACT_641} P05121 Plasminogen activator inhibitor 1 protein 20100318 {GO:0033629=IDA, GO:0005515=IPI, GO:0010467=TAS, GO:0010469=IDA, GO:0035491=IMP, GO:0006367=TAS, GO:0005886=TAS, GO:0004867=IPI, GO:2000098=IDA, GO:0002020=IPI, GO:0005615=IDA, GO:0014912=IDA, GO:0032757=IMP, GO:0061044=IGI, GO:0061045=IC, GO:0042127=IEA, GO:0045944=TAS, GO:0007179=TAS, GO:0031093=TAS, GO:0030336=IDA, GO:0043066=IMP, GO:0005102=IPI, GO:0051918=IDA, GO:0030168=TAS, GO:0005576=IDA, GO:0070887=IMP, GO:0001525=IEP, GO:0006351=TAS, GO:0045766=IMP, GO:0031012=IDA, GO:0010951=IDA, GO:0050829=IGI, GO:0071222=IMP, GO:0030194=IMP, GO:0007596=TAS, GO:0030195=IC, GO:0048260=IDA, GO:0050729=IGI, GO:0002576=TAS, GO:0001300=IEP, GO:0010757=IDA, GO:0090026=IMP, GO:0042730=TAS} angiogenesis, blood coagulation, cellular response to chemical stimulus, cellular response to lipopolysaccharide, chronological cell aging, defense response to Gram-negative bacterium, fibrinolysis, gene expression, negative regulation of apoptotic process, negative regulation of blood coagulation, negative regulation of cell adhesion mediated by integrin, negative regulation of cell migration, negative regulation of endopeptidase activity, negative regulation of fibrinolysis, negative regulation of plasminogen activation, negative regulation of smooth muscle cell migration, negative regulation of smooth muscle cell-matrix adhesion, negative regulation of vascular wound healing, negative regulation of wound healing, platelet activation, platelet degranulation, positive regulation of angiogenesis, positive regulation of blood coagulation, positive regulation of inflammatory response, positive regulation of interleukin-8 production, positive regulation of leukotriene production involved in inflammatory response, positive regulation of monocyte chemotaxis, positive regulation of receptor-mediated endocytosis, positive regulation of transcription from RNA polymerase II promoter, regulation of cell proliferation, regulation of receptor activity, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway extracellular matrix, extracellular region, extracellular space, plasma membrane, platelet alpha granule lumen protease binding, protein binding, receptor binding, serine-type endopeptidase inhibitor activity Human SERPINE2 BHF-UCL UniProtKB {GO:0005515=PMID:3279057, GO:0010544=GO_REF:0000019, GO:0030308=GO_REF:0000019, GO:0031594=PMID:2037625, GO:0008285=GO_REF:0000019, GO:0061108=GO_REF:0000019, GO:0004867=PMID:19249338, GO:0045879=GO_REF:0000019, GO:0060291=GO_REF:0000019, GO:0005539=PMID:19855083, GO:0005615=GO_REF:0000033, GO:0005829=PMID:19855083, GO:0042628=GO_REF:0000019, GO:0010766=GO_REF:0000019, GO:0031091=PMID:19855083, GO:0008201=PMID:3997857, GO:0033363=GO_REF:0000019, GO:0030334=PMID:2877744, GO:0048505=GO_REF:0000019, GO:0051966=GO_REF:0000019, GO:0042177=GO_REF:0000019, GO:0021683=GO_REF:0000019, GO:0005102=PMID:17379830, GO:0090331=PMID:19855083, GO:0005576=PMID:3997857, GO:0014067=GO_REF:0000019, GO:0031232=PMID:19855083, GO:0045861=PMID:3997857, GO:0031012=PMID:3279057, GO:0010951=GO_REF:0000033, GO:0060384=GO_REF:0000019, GO:0048711=PMID:1691280, GO:0007596=GO_REF:0000019, GO:0030195=PMID:19855083, GO:0050974=GO_REF:0000019, GO:0010757=PMID:19855083, GO:0010955=PMID:19855083, GO:0032940=GO_REF:0000019, GO:0044421=GO_REF:0000019} P07093 Glia-derived nexin protein 20100517 {GO:0005515=IPI, GO:0010544=IEA, GO:0030308=IEA, GO:0031594=ISS, GO:0008285=IEA, GO:0061108=IEA, GO:0004867=IDA, GO:0045879=IEA, GO:0060291=IEA, GO:0005539=IDA, GO:0005615=IBA, GO:0005829=IDA, GO:0042628=IEA, GO:0010766=IEA, GO:0031091=IMP, GO:0008201=IDA, GO:0033363=IEA, GO:0030334=NAS, GO:0048505=IEA, GO:0051966=IEA, GO:0042177=IEA, GO:0021683=IEA, GO:0005102=IPI, GO:0090331=ISS, GO:0005576=IDA, GO:0014067=IEA, GO:0031232=IDA, GO:0045861=IDA, GO:0031012=IDA, GO:0010951=IBA, GO:0060384=IEA, GO:0048711=IDA, GO:0007596=IEA, GO:0030195=IC, GO:0050974=IEA, GO:0010757=IMP, GO:0010955=IC, GO:0032940=IEA, GO:0044421=IEA} blood coagulation, cerebellar granular layer morphogenesis, detection of mechanical stimulus involved in sensory perception, innervation, long-term synaptic potentiation, mating plug formation, negative regulation of blood coagulation, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of endopeptidase activity, negative regulation of phosphatidylinositol 3-kinase cascade, negative regulation of plasminogen activation, negative regulation of platelet activation, negative regulation of platelet aggregation, negative regulation of protein catabolic process, negative regulation of protein processing, negative regulation of proteolysis, negative regulation of smoothened signaling pathway, negative regulation of sodium ion transport, positive regulation of astrocyte differentiation, regulation of cell migration, regulation of synaptic transmission, glutamatergic, regulation of timing of cell differentiation, secretion by cell, secretory granule organization, seminal vesicle epithelium development cytosol, extracellular matrix, extracellular region, extracellular region part, extracellular space, extrinsic to external side of plasma membrane, neuromuscular junction, platelet alpha granule glycosaminoglycan binding, heparin binding, protein binding, receptor binding, serine-type endopeptidase inhibitor activity Human UniProtKB:Q07235 SERPINF1 PINC UniProtKB {GO:0030162=GO_REF:0000033, GO:0010951=GO_REF:0000033, GO:0060770=GO_REF:0000019, GO:0042470=GO_REF:0000039, GO:0008283=PMID:8473338, GO:0050769=PMID:8226833, GO:0004867=GO_REF:0000033, GO:0016525=PMID:11562499, GO:0007275=PMID:8473338, GO:0005576=PMID:12737624, GO:0005615=GO_REF:0000019} P36955 Pigment epithelium-derived factor protein 20030904 {GO:0030162=IBA, GO:0010951=IBA, GO:0060770=IEA, GO:0042470=IEA, GO:0008283=TAS, GO:0050769=IDA, GO:0004867=IBA, GO:0016525=IDA, GO:0007275=TAS, GO:0005576=IDA, GO:0005615=IEA} cell proliferation, multicellular organismal development, negative regulation of angiogenesis, negative regulation of endopeptidase activity, negative regulation of epithelial cell proliferation involved in prostate gland development, positive regulation of neurogenesis, regulation of proteolysis extracellular region, extracellular space, melanosome serine-type endopeptidase inhibitor activity Human SERPINF2 BHF-UCL UniProtKB {GO:0005515=PMID:14687906, GO:0004866=PMID:2830248, GO:0004867=PMID:134998, GO:0045597=GO_REF:0000019, GO:0048514=GO_REF:0000024, GO:2000049=PMID:17203182, GO:0002020=PMID:17317851, GO:0005615=PMID:6980881, GO:0042803=PMID:134998, GO:0071636=PMID:17958745, GO:0030162=GO_REF:0000033, GO:0045944=PMID:17958745, GO:0030199=PMID:17958745, GO:0031093=Reactome:REACT_21351, GO:0010033=GO_REF:0000019, GO:0005577=PMID:17317851, GO:0051918=PMID:134998, GO:0002034=GO_REF:0000024, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_21351, GO:0006953=GO_REF:0000037, GO:0048661=GO_REF:0000024, GO:0010951=GO_REF:0000033, GO:0032967=PMID:17958745, GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0010757=PMID:134998, GO:0042730=Reactome:REACT_641} P08697 Alpha-2-antiplasmin protein 20111202 {GO:0005515=IPI, GO:0004866=TAS, GO:0004867=IDA, GO:0045597=IEA, GO:0048514=ISS, GO:2000049=TAS, GO:0002020=IPI, GO:0005615=IDA, GO:0042803=IPI, GO:0071636=IDA, GO:0030162=IBA, GO:0045944=IDA, GO:0030199=ISS, GO:0031093=TAS, GO:0010033=IEA, GO:0005577=IDA, GO:0051918=IDA, GO:0002034=ISS, GO:0030168=TAS, GO:0005576=TAS, GO:0006953=IEA, GO:0048661=ISS, GO:0010951=IBA, GO:0032967=IDA, GO:0007596=TAS, GO:0002576=TAS, GO:0010757=IDA, GO:0042730=TAS} acute-phase response, blood coagulation, blood vessel morphogenesis, collagen fibril organization, fibrinolysis, negative regulation of endopeptidase activity, negative regulation of fibrinolysis, negative regulation of plasminogen activation, platelet activation, platelet degranulation, positive regulation of cell differentiation, positive regulation of cell-cell adhesion mediated by cadherin, positive regulation of collagen biosynthetic process, positive regulation of smooth muscle cell proliferation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transforming growth factor beta production, regulation of blood vessel size by renin-angiotensin, regulation of proteolysis, response to organic substance extracellular region, extracellular space, fibrinogen complex, platelet alpha granule lumen endopeptidase inhibitor activity, protease binding, protein binding, protein homodimerization activity, serine-type endopeptidase inhibitor activity Human UniProtKB:Q61247 SERPING1 Reactome UniProtKB {GO:0005515=PMID:10946292, GO:0001869=PMID:10946292, GO:0004867=PMID:11527969, GO:0008015=PMID:2563376, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_21351, GO:0005615=GO_REF:0000033, GO:0010951=GO_REF:0000033, GO:0007596=Reactome:REACT_2051, GO:0007597=Reactome:REACT_326, GO:0045087=GO_REF:0000037, GO:0006958=GO_REF:0000037, GO:0002576=Reactome:REACT_318, GO:0006508=GO_REF:0000038, GO:0031093=Reactome:REACT_21351, GO:0008233=GO_REF:0000038, GO:0042730=GO_REF:0000037} P05155 Plasma protease C1 inhibitor protein 20130213 {GO:0005515=IPI, GO:0001869=IDA, GO:0004867=IDA, GO:0008015=TAS, GO:0030168=TAS, GO:0005576=TAS, GO:0005615=IBA, GO:0010951=IBA, GO:0007596=TAS, GO:0007597=TAS, GO:0045087=IEA, GO:0006958=IEA, GO:0002576=TAS, GO:0006508=IEA, GO:0031093=TAS, GO:0008233=IEA, GO:0042730=IEA} blood circulation, blood coagulation, blood coagulation, intrinsic pathway, complement activation, classical pathway, fibrinolysis, innate immune response, negative regulation of complement activation, lectin pathway, negative regulation of endopeptidase activity, platelet activation, platelet degranulation, proteolysis extracellular region, extracellular space, platelet alpha granule lumen peptidase activity, protein binding, serine-type endopeptidase inhibitor activity Human SERPINH1 HPA UniProtKB {GO:0006986=PMID:10023073, GO:0005793=PMID:15308636, GO:0004867=GO_REF:0000033, GO:0005783=GO_REF:0000052, GO:0005518=PMID:7656593, GO:0010951=GO_REF:0000033, GO:0030162=GO_REF:0000033, GO:0051604=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0030199=GO_REF:0000019, GO:0005788=Reactome:REACT_121366, GO:0032964=GO_REF:0000019, GO:0051082=GO_REF:0000019} P50454 Serpin H1 protein 20101115 {GO:0006986=TAS, GO:0005793=IDA, GO:0004867=IBA, GO:0005783=IDA, GO:0005518=NAS, GO:0010951=IBA, GO:0030162=IBA, GO:0051604=IEA, GO:0005737=IEA, GO:0030198=TAS, GO:0030199=IEA, GO:0005788=TAS, GO:0032964=IEA, GO:0051082=IEA} collagen biosynthetic process, collagen fibril organization, extracellular matrix organization, negative regulation of endopeptidase activity, protein maturation, regulation of proteolysis, response to unfolded protein cytoplasm, endoplasmic reticulum, endoplasmic reticulum lumen, endoplasmic reticulum-Golgi intermediate compartment collagen binding, serine-type endopeptidase inhibitor activity, unfolded protein binding Human SERPINI1 PINC UniProtKB {GO:0030162=GO_REF:0000033, GO:0010951=GO_REF:0000033, GO:0004867=GO_REF:0000033, GO:0007422=PMID:9070919, GO:0005576=GO_REF:0000039, GO:0007417=PMID:9070919, GO:0030155=GO_REF:0000019} Q99574 Neuroserpin protein 20030904 {GO:0030162=IBA, GO:0010951=IBA, GO:0004867=IBA, GO:0007422=TAS, GO:0005576=IEA, GO:0007417=TAS, GO:0030155=IEA} central nervous system development, negative regulation of endopeptidase activity, peripheral nervous system development, regulation of cell adhesion, regulation of proteolysis extracellular region serine-type endopeptidase inhibitor activity Human SERPINI2 PINC UniProtKB {GO:0030162=GO_REF:0000033, GO:0010951=GO_REF:0000033, GO:0004867=GO_REF:0000033, GO:0006928=PMID:10097100, GO:0005576=GO_REF:0000039} O75830 Serpin I2 protein 20030904 {GO:0030162=IBA, GO:0010951=IBA, GO:0004867=IBA, GO:0006928=TAS, GO:0005576=IEA} cellular component movement, negative regulation of endopeptidase activity, regulation of proteolysis extracellular region serine-type endopeptidase inhibitor activity Human SERTAD1 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0008284=PMID:6434876, GO:0000079=PMID:6434876, GO:0045893=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q9UHV2 SERTA domain-containing protein 1 protein 20130415 {GO:0005515=IPI, GO:0008284=TAS, GO:0000079=TAS, GO:0045893=IEA, GO:0006351=IEA} positive regulation of cell proliferation, positive regulation of transcription, DNA-dependent, regulation of cyclin-dependent protein serine/threonine kinase activity, transcription, DNA-dependent protein binding Human UniProtKB:Q8WTS6 SERTAD2 MGI UniProtKB {GO:0030308=PMID:16098148, GO:0005737=PMID:16098148, GO:0003713=GO_REF:0000019, GO:0005634=PMID:16098148, GO:0045893=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q14140 SERTA domain-containing protein 2 protein 20060818 {GO:0030308=IDA, GO:0005737=IDA, GO:0003713=IEA, GO:0005634=IDA, GO:0045893=IEA, GO:0006351=IEA} negative regulation of cell growth, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus transcription coactivator activity Human SERTAD3 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0030308=PMID:16098148, GO:0005634=PMID:16098148, GO:0045893=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q9UJW9 SERTA domain-containing protein 3 protein 20130415 {GO:0005515=IPI, GO:0030308=IDA, GO:0005634=IDA, GO:0045893=IEA, GO:0006351=IEA} negative regulation of cell growth, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus protein binding Human UniProtKB:Q8N6Y0 SERTAD4 null null {} null null null null {} null null null SERTM1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} A2A2V5 Serine-rich and transmembrane domain-containing protein 1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 SESN1 PINC UniProtKB {GO:0008285=PMID:9926927, GO:0005634=GO_REF:0000039, GO:0007050=GO_REF:0000002, GO:0006974=PMID:9926927} Q9Y6P5 Sestrin-1 protein 20030904 {GO:0008285=TAS, GO:0005634=IEA, GO:0007050=IEA, GO:0006974=TAS} cell cycle arrest, negative regulation of cell proliferation, response to DNA damage stimulus nucleus Human SESN2 LIFEdb UniProtKB {GO:0005737=GO_REF:0000054, GO:0007050=GO_REF:0000002, GO:0005634=GO_REF:0000002} P58004 Sestrin-2 protein 20100607 {GO:0005737=IDA, GO:0007050=IEA, GO:0005634=IEA} cell cycle arrest cytoplasm, nucleus Human SESN3 InterPro UniProtKB {GO:0007050=GO_REF:0000002, GO:0005634=GO_REF:0000002} P58005 Sestrin-3 protein 20130413 {GO:0007050=IEA, GO:0005634=IEA} cell cycle arrest nucleus Human InterPro:IPR006730 SESTD1 UniProtKB UniProtKB {GO:0005515=PMID:20164195, GO:0005545=PMID:20164195, GO:0070300=PMID:20164195, GO:0043325=PMID:20164195, GO:0001786=PMID:20164195, GO:0070273=PMID:20164195, GO:0080025=PMID:20164195, GO:0005546=PMID:20164195, GO:0031210=PMID:20164195, GO:0032266=PMID:20164195, GO:0034704=PMID:20164195, GO:0010314=PMID:20164195} Q86VW0 SEC14 domain and spectrin repeat-containing protein 1 protein 20100514 {GO:0005515=IPI, GO:0005545=IDA, GO:0070300=IDA, GO:0043325=IDA, GO:0001786=IDA, GO:0070273=IDA, GO:0080025=IDA, GO:0005546=IDA, GO:0031210=IDA, GO:0032266=IDA, GO:0034704=IPI, GO:0010314=IDA} calcium channel complex 1-phosphatidylinositol binding, phosphatidic acid binding, phosphatidylcholine binding, phosphatidylinositol-3,4-bisphosphate binding, phosphatidylinositol-3,5-bisphosphate binding, phosphatidylinositol-3-phosphate binding, phosphatidylinositol-4,5-bisphosphate binding, phosphatidylinositol-4-phosphate binding, phosphatidylinositol-5-phosphate binding, phosphatidylserine binding, protein binding NOT Human SET InterPro UniProtKB {GO:0005515=PMID:20195357, GO:0010467=Reactome:REACT_71, GO:0048471=PMID:12524539, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0005783=PMID:12524539, GO:0004864=PMID:8626647, GO:0008601=PMID:11555662, GO:0006334=GO_REF:0000002, GO:0005634=GO_REF:0000002, GO:0006337=PMID:11555662, GO:0035067=PMID:11555662, GO:0003677=GO_REF:0000037, GO:0005829=GO_REF:0000039, GO:0006913=PMID:11555662, GO:0006260=PMID:7753797, GO:0043234=PMID:11909973, GO:0042393=PMID:11555662, GO:0043524=PMID:18374643, GO:0005737=PMID:11909973, GO:0005654=Reactome:REACT_25286, GO:0045892=PMID:19343227} Q5VXV2 Protein SET protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0048471=IDA, GO:0016070=TAS, GO:0016071=TAS, GO:0005783=IDA, GO:0004864=TAS, GO:0008601=TAS, GO:0006334=IEA, GO:0005634=IEA, GO:0006337=TAS, GO:0035067=TAS, GO:0003677=IEA, GO:0005829=IEA, GO:0006913=NAS, GO:0006260=TAS, GO:0043234=IDA, GO:0042393=TAS, GO:0043524=IGI, GO:0005737=IDA, GO:0005654=TAS, GO:0045892=IDA} DNA replication, RNA metabolic process, gene expression, mRNA metabolic process, negative regulation of histone acetylation, negative regulation of neuron apoptotic process, negative regulation of transcription, DNA-dependent, nucleocytoplasmic transport, nucleosome assembly, nucleosome disassembly cytoplasm, cytosol, endoplasmic reticulum, nucleoplasm, nucleus, perinuclear region of cytoplasm, protein complex DNA binding, histone binding, protein binding, protein phosphatase inhibitor activity, protein phosphatase type 2A regulator activity Human InterPro:IPR002164 SETBP1 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037} Q9Y6X0 SET-binding protein protein 20130413 {GO:0005634=IEA, GO:0003677=IEA} nucleus DNA binding Human UniProtKB-SubCell:SL-0191 SETD1A GOC UniProtKB {GO:0005515=PMID:12670868, GO:0006355=GO_REF:0000037, GO:0005694=GO_REF:0000039, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0042800=PMID:20862685, GO:0006351=GO_REF:0000037, GO:0035097=PMID:17500065, GO:0000166=GO_REF:0000002, GO:0016607=GO_REF:0000039, GO:0048188=PMID:17998332, GO:0051568=PMID:20862685} O15047 Histone-lysine N-methyltransferase SETD1A protein 20130413 {GO:0005515=IPI, GO:0006355=IEA, GO:0005694=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0042800=IDA, GO:0006351=IEA, GO:0035097=IDA, GO:0000166=IEA, GO:0016607=IEA, GO:0048188=IDA, GO:0051568=IDA} histone H3-K4 methylation, regulation of transcription, DNA-dependent, transcription, DNA-dependent Set1C/COMPASS complex, chromosome, histone methyltransferase complex, nuclear speck, nucleolus, nucleus RNA binding, histone methyltransferase activity (H3-K4 specific), nucleic acid binding, nucleotide binding, protein binding Human SETD1B HPA UniProtKB {GO:0005515=PMID:17998332, GO:0006355=GO_REF:0000037, GO:0005694=GO_REF:0000039, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0042800=PMID:17355966, GO:0006351=GO_REF:0000037, GO:0035097=PMID:17355966, GO:0000166=GO_REF:0000002, GO:0016607=GO_REF:0000039, GO:0048188=PMID:17998332, GO:0051568=PMID:17355966} Q9UPS6 Histone-lysine N-methyltransferase SETD1B protein 20090616 {GO:0005515=IPI, GO:0006355=IEA, GO:0005694=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0042800=IDA, GO:0006351=IEA, GO:0035097=IDA, GO:0000166=IEA, GO:0016607=IEA, GO:0048188=IDA, GO:0051568=IDA} histone H3-K4 methylation, regulation of transcription, DNA-dependent, transcription, DNA-dependent Set1C/COMPASS complex, chromosome, histone methyltransferase complex, nuclear speck, nucleolus, nucleus RNA binding, histone methyltransferase activity (H3-K4 specific), nucleotide binding, protein binding NOT Human SETD2 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0010468=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0005694=GO_REF:0000039, GO:0010452=GO_REF:0000019, GO:0046914=GO_REF:0000002, GO:0001843=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0001525=GO_REF:0000019, GO:0048864=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0060039=GO_REF:0000019, GO:0048701=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0018023=GO_REF:0000019, GO:0018024=GO_REF:0000003, GO:0060977=GO_REF:0000019, GO:0060669=GO_REF:0000019, GO:0035441=GO_REF:0000019, GO:0016491=GO_REF:0000002, GO:0048332=GO_REF:0000019, GO:0030900=GO_REF:0000019, GO:0001763=GO_REF:0000019} Q9BYW2 Histone-lysine N-methyltransferase SETD2 protein 20130415 {GO:0005515=IPI, GO:0010468=IEA, GO:0006355=IEA, GO:0005694=IEA, GO:0010452=IEA, GO:0046914=IEA, GO:0001843=IEA, GO:0005634=IEA, GO:0001525=IEA, GO:0048864=IEA, GO:0003677=IEA, GO:0060039=IEA, GO:0048701=IEA, GO:0006351=IEA, GO:0018023=IEA, GO:0018024=IEA, GO:0060977=IEA, GO:0060669=IEA, GO:0035441=IEA, GO:0016491=IEA, GO:0048332=IEA, GO:0030900=IEA, GO:0001763=IEA} angiogenesis, cell migration involved in vasculogenesis, coronary vasculature morphogenesis, embryonic cranial skeleton morphogenesis, embryonic placenta morphogenesis, forebrain development, histone H3-K36 methylation, mesoderm morphogenesis, morphogenesis of a branching structure, neural tube closure, peptidyl-lysine trimethylation, pericardium development, regulation of gene expression, regulation of transcription, DNA-dependent, stem cell development, transcription, DNA-dependent chromosome, nucleus DNA binding, histone-lysine N-methyltransferase activity, oxidoreductase activity, protein binding, transition metal ion binding Human UniProtKB:P84022 SETD3 UniProtKB UniProtKB {GO:0001102=GO_REF:0000019, GO:0000790=GO_REF:0000019, GO:0003713=GO_REF:0000024, GO:0010452=GO_REF:0000024, GO:0018027=GO_REF:0000024, GO:0042800=GO_REF:0000019, GO:0018026=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0018023=GO_REF:0000024, GO:0051149=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0046975=GO_REF:0000024, GO:0045893=GO_REF:0000024} Q86TU7 Histone-lysine N-methyltransferase setd3 protein 20110316 {GO:0001102=IEA, GO:0000790=IEA, GO:0003713=ISS, GO:0010452=ISS, GO:0018027=ISS, GO:0042800=IEA, GO:0018026=ISS, GO:0006351=IEA, GO:0018023=ISS, GO:0051149=IEA, GO:0045944=IEA, GO:0046975=ISS, GO:0045893=ISS} histone H3-K36 methylation, peptidyl-lysine dimethylation, peptidyl-lysine monomethylation, peptidyl-lysine trimethylation, positive regulation of muscle cell differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent nuclear chromatin RNA polymerase II activating transcription factor binding, histone methyltransferase activity (H3-K36 specific), histone methyltransferase activity (H3-K4 specific), transcription coactivator activity Human UniProtKB:Q7SXS7 SETD4 null null {} null null null null {} null null null SETD5 null null {} null null null null {} null null null SETD6 IntAct UniProtKB {GO:0005515=PMID:21131967, GO:0051059=PMID:21131967, GO:0050727=PMID:21131967, GO:0032088=PMID:21131967, GO:0005634=PMID:21131967, GO:0016279=PMID:21131967, GO:0018026=PMID:21131967} Q8TBK2 N-lysine methyltransferase SETD6 protein 20130415 {GO:0005515=IPI, GO:0051059=IPI, GO:0050727=IMP, GO:0032088=IMP, GO:0005634=IDA, GO:0016279=IDA, GO:0018026=IDA} negative regulation of NF-kappaB transcription factor activity, peptidyl-lysine monomethylation, regulation of inflammatory response nucleus NF-kappaB binding, protein binding, protein-lysine N-methyltransferase activity Human UniProtKB:Q04207 SETD7 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0002039=PMID:17108971, GO:0006355=GO_REF:0000037, GO:0005694=GO_REF:0000039, GO:0018027=PMID:17108971, GO:0005634=GO_REF:0000039, GO:0016279=PMID:17108971, GO:0018026=PMID:17108971, GO:0006351=GO_REF:0000037, GO:0016568=PMID:12514135, GO:0018024=PMID:17707234} Q8WTS6 Histone-lysine N-methyltransferase SETD7 protein 20130415 {GO:0005515=IPI, GO:0002039=IPI, GO:0006355=IEA, GO:0005694=IEA, GO:0018027=IDA, GO:0005634=IEA, GO:0016279=IDA, GO:0018026=IDA, GO:0006351=IEA, GO:0016568=NAS, GO:0018024=IDA} chromatin modification, peptidyl-lysine dimethylation, peptidyl-lysine monomethylation, regulation of transcription, DNA-dependent, transcription, DNA-dependent chromosome, nucleus histone-lysine N-methyltransferase activity, p53 binding, protein binding, protein-lysine N-methyltransferase activity Human UniProtKB:Q9UHV2 SETD8 GOC UniProtKB {GO:0005515=PMID:15933069, GO:0005694=GO_REF:0000039, GO:0003714=PMID:18408754, GO:0034968=PMID:17707234, GO:0005634=GO_REF:0000039, GO:0000122=PMID:17707234, GO:0018026=PMID:17707234, GO:0016279=PMID:17707234, GO:0006351=GO_REF:0000037, GO:0018024=PMID:17707234, GO:0002039=PMID:17707234, GO:0007067=GO_REF:0000037, GO:0043516=PMID:17707234, GO:0045892=PMID:18474616, GO:0051301=GO_REF:0000037} Q9NQR1 N-lysine methyltransferase SETD8 protein 20130413 {GO:0005515=IPI, GO:0005694=IEA, GO:0003714=IDA, GO:0034968=IDA, GO:0005634=IEA, GO:0000122=IMP, GO:0018026=IDA, GO:0016279=IDA, GO:0006351=IEA, GO:0018024=IDA, GO:0002039=IPI, GO:0007067=IEA, GO:0043516=IMP, GO:0045892=IDA, GO:0051301=IEA} cell division, histone lysine methylation, mitosis, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, peptidyl-lysine monomethylation, regulation of DNA damage response, signal transduction by p53 class mediator, transcription, DNA-dependent chromosome, nucleus histone-lysine N-methyltransferase activity, p53 binding, protein binding, protein-lysine N-methyltransferase activity, transcription corepressor activity Human SETDB1 HPA UniProtKB {GO:0005515=PMID:21170338, GO:0006355=GO_REF:0000037, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005694=GO_REF:0000039, GO:0001833=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0018024=GO_REF:0000003, GO:0005737=GO_REF:0000052, GO:0008270=GO_REF:0000002} Q15047 Histone-lysine N-methyltransferase SETDB1 protein 20101115 {GO:0005515=IPI, GO:0006355=IEA, GO:0005794=IDA, GO:0005886=IDA, GO:0005694=IEA, GO:0001833=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA, GO:0018024=IEA, GO:0005737=IDA, GO:0008270=IEA} inner cell mass cell proliferation, regulation of transcription, DNA-dependent, transcription, DNA-dependent Golgi apparatus, chromosome, cytoplasm, nucleolus, nucleus, plasma membrane DNA binding, histone-lysine N-methyltransferase activity, protein binding, zinc ion binding Human SETDB2 UniProtKB UniProtKB {GO:0001947=GO_REF:0000024, GO:0007067=PMID:20404330, GO:0007059=PMID:20404330, GO:0005694=GO_REF:0000039, GO:0046974=PMID:20404330, GO:0005634=PMID:20404330, GO:0008270=GO_REF:0000002, GO:0070986=GO_REF:0000024, GO:0045892=GO_REF:0000024, GO:0003677=GO_REF:0000002, GO:0051567=PMID:20404330, GO:0051301=GO_REF:0000037} Q96T68 Histone-lysine N-methyltransferase SETDB2 protein 20100730 {GO:0001947=ISS, GO:0007067=IMP, GO:0007059=IMP, GO:0005694=IEA, GO:0046974=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0070986=ISS, GO:0045892=ISS, GO:0003677=IEA, GO:0051567=IDA, GO:0051301=IEA} cell division, chromosome segregation, heart looping, histone H3-K9 methylation, left/right axis specification, mitosis, negative regulation of transcription, DNA-dependent chromosome, nucleus DNA binding, histone methyltransferase activity (H3-K9 specific), zinc ion binding Human UniProtKB:Q06ZW3 SETMAR UniProtKB UniProtKB {GO:0005515=PMID:19390626, GO:0071157=PMID:19390626, GO:0005694=GO_REF:0000039, GO:0005634=PMID:21491884, GO:0015074=GO_REF:0000002, GO:0003677=GO_REF:0000002, GO:0006313=PMID:9461395, GO:0042803=PMID:20521842, GO:0004803=PMID:21491884, GO:0018024=GO_REF:0000003, GO:0004519=PMID:20620605, GO:2001251=PMID:20620605, GO:0043566=PMID:20521842, GO:0008270=GO_REF:0000002, GO:0000737=PMID:20521842, GO:2001034=PMID:20620605, GO:0000729=PMID:21491884} Q53H47 Histone-lysine N-methyltransferase SETMAR protein 20111202 {GO:0005515=IPI, GO:0071157=IMP, GO:0005694=IEA, GO:0005634=IC, GO:0015074=IEA, GO:0003677=IEA, GO:0006313=TAS, GO:0042803=IPI, GO:0004803=TAS, GO:0018024=IEA, GO:0004519=IDA, GO:2001251=IDA, GO:0043566=IDA, GO:0008270=IEA, GO:0000737=IDA, GO:2001034=IDA, GO:0000729=IDA} DNA catabolic process, endonucleolytic, DNA double-strand break processing, DNA integration, negative regulation of cell cycle arrest, negative regulation of chromosome organization, positive regulation of double-strand break repair via nonhomologous end joining, transposition, DNA-mediated chromosome, nucleus DNA binding, endonuclease activity, histone-lysine N-methyltransferase activity, protein binding, protein homodimerization activity, structure-specific DNA binding, transposase activity, zinc ion binding Human SETX GOC UniProtKB {GO:0008219=GO_REF:0000037, GO:0006369=GO_REF:0000019, GO:0006396=PMID:17562789, GO:0005730=GO_REF:0000039, GO:0005634=PMID:17562789, GO:0005524=GO_REF:0000037, GO:0003677=PMID:17562789, GO:0003678=PMID:17562789, GO:0006302=PMID:17562789, GO:0005737=PMID:17562789, GO:0007623=GO_REF:0000019, GO:0005654=PMID:17562789, GO:0032508=PMID:17562789} Q7Z333 Probable helicase senataxin protein 20130413 {GO:0008219=IEA, GO:0006369=IEA, GO:0006396=TAS, GO:0005730=IEA, GO:0005634=IDA, GO:0005524=IEA, GO:0003677=IC, GO:0003678=TAS, GO:0006302=IDA, GO:0005737=IDA, GO:0007623=IEA, GO:0005654=IDA, GO:0032508=TAS} DNA duplex unwinding, RNA processing, cell death, circadian rhythm, double-strand break repair, termination of RNA polymerase II transcription cytoplasm, nucleolus, nucleoplasm, nucleus ATP binding, DNA binding, DNA helicase activity Human SEZ6 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0043197=GO_REF:0000019, GO:0043198=GO_REF:0000019, GO:0060079=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:2000171=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:1900006=GO_REF:0000019} Q53EL9 Seizure protein 6 homolog protein 20130413 {GO:0005886=IEA, GO:0043197=IEA, GO:0043198=IEA, GO:0060079=IEA, GO:0016021=IEA, GO:2000171=IEA, GO:0005615=IEA, GO:1900006=IEA} negative regulation of dendrite development, positive regulation of dendrite development, regulation of excitatory postsynaptic membrane potential dendritic shaft, dendritic spine, extracellular space, integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 SEZ6L2 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q6UXD5 Seizure 6-like protein 2 protein 20130413 {GO:0005886=IEA, GO:0005789=IEA, GO:0016021=IEA} endoplasmic reticulum membrane, integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 SF1 HPA UniProtKB {GO:0000245=PMID:8752089, GO:0006355=GO_REF:0000037, GO:0003714=PMID:9660765, GO:0003723=PMID:8752089, GO:0005730=GO_REF:0000052, GO:0050810=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0022402=GO_REF:0000019, GO:0003676=GO_REF:0000029, GO:0006351=GO_REF:0000037, GO:0000389=PMID:15647371, GO:0000398=PMID:9731529, GO:0030238=GO_REF:0000019, GO:0033327=GO_REF:0000019, GO:0005840=PMID:8752089, GO:0005681=PMID:9731529, GO:0008270=GO_REF:0000002} Q15637 Splicing factor 1 protein 20081203 {GO:0000245=NAS, GO:0006355=IEA, GO:0003714=TAS, GO:0003723=TAS, GO:0005730=IDA, GO:0050810=IEA, GO:0005634=IDA, GO:0022402=IEA, GO:0003676=NAS, GO:0006351=IEA, GO:0000389=TAS, GO:0000398=IC, GO:0030238=IEA, GO:0033327=IEA, GO:0005840=NAS, GO:0005681=IDA, GO:0008270=IEA} Leydig cell differentiation, cell cycle process, mRNA 3'-splice site recognition, mRNA splicing, via spliceosome, male sex determination, regulation of steroid biosynthetic process, regulation of transcription, DNA-dependent, spliceosomal complex assembly, transcription, DNA-dependent nucleolus, nucleus, ribosome, spliceosomal complex RNA binding, nucleic acid binding, transcription corepressor activity, zinc ion binding NOT Human SF3A1 HPA UniProtKB {GO:0005515=PMID:20562859, GO:0006397=PMID:15647371, GO:0008380=Reactome:REACT_1735, GO:0006396=GO_REF:0000002, GO:0010467=Reactome:REACT_71, GO:0003723=PMID:10882114, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0071013=PMID:11991638, GO:0000389=PMID:15647371, GO:0000398=Reactome:REACT_467, GO:0005684=PMID:10882114, GO:0005681=PMID:9731529, GO:0005654=Reactome:REACT_1935} Q15459 Splicing factor 3A subunit 1 protein 20080205 {GO:0005515=IPI, GO:0006397=IMP, GO:0008380=TAS, GO:0006396=IEA, GO:0010467=TAS, GO:0003723=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0071013=IDA, GO:0000389=TAS, GO:0000398=TAS, GO:0005684=IDA, GO:0005681=IDA, GO:0005654=TAS} RNA processing, RNA splicing, gene expression, mRNA 3'-splice site recognition, mRNA processing, mRNA splicing, via spliceosome U2-type spliceosomal complex, catalytic step 2 spliceosome, nucleolus, nucleoplasm, nucleus, spliceosomal complex RNA binding, protein binding NOT Human SF3A2 Reactome UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0006397=PMID:15647371, GO:0010467=Reactome:REACT_71, GO:0000398=Reactome:REACT_467, GO:0030532=PMID:8211113, GO:0005654=Reactome:REACT_1935, GO:0005681=PMID:9731529, GO:0005634=GO_REF:0000038, GO:0008270=GO_REF:0000002, GO:0071013=PMID:11991638, GO:0003676=GO_REF:0000002, GO:0000389=PMID:15647371} Q15428 Splicing factor 3A subunit 2 protein 20130213 {GO:0008380=TAS, GO:0006397=IMP, GO:0010467=TAS, GO:0000398=TAS, GO:0030532=TAS, GO:0005654=TAS, GO:0005681=IDA, GO:0005634=IEA, GO:0008270=IEA, GO:0071013=IDA, GO:0003676=IEA, GO:0000389=TAS} RNA splicing, gene expression, mRNA 3'-splice site recognition, mRNA processing, mRNA splicing, via spliceosome catalytic step 2 spliceosome, nucleoplasm, nucleus, small nuclear ribonucleoprotein complex, spliceosomal complex nucleic acid binding, zinc ion binding Human SF3A3 HPA UniProtKB {GO:0005515=PMID:22190034, GO:0006397=PMID:15647371, GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0071013=PMID:11991638, GO:0000389=PMID:15647371, GO:0016607=GO_REF:0000039, GO:0000398=Reactome:REACT_467, GO:0000375=PMID:7816610, GO:0005654=Reactome:REACT_1935, GO:0008270=GO_REF:0000002, GO:0005681=PMID:9731529} Q12874 Splicing factor 3A subunit 3 protein 20101115 {GO:0005515=IPI, GO:0006397=IMP, GO:0008380=TAS, GO:0010467=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0071013=IDA, GO:0000389=TAS, GO:0016607=IEA, GO:0000398=TAS, GO:0000375=TAS, GO:0005654=TAS, GO:0008270=IEA, GO:0005681=IDA} RNA splicing, RNA splicing, via transesterification reactions, gene expression, mRNA 3'-splice site recognition, mRNA processing, mRNA splicing, via spliceosome catalytic step 2 spliceosome, nuclear speck, nucleolus, nucleoplasm, nucleus, spliceosomal complex nucleic acid binding, protein binding, zinc ion binding NOT Human SF3B1 Reactome UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0016607=GO_REF:0000039, GO:0000398=Reactome:REACT_1753, GO:0000375=PMID:9585501, GO:0003682=GO_REF:0000019, GO:0005654=Reactome:REACT_2241, GO:0005634=PMID:18559850, GO:0005681=PMID:9585501, GO:0071013=PMID:11991638, GO:0009952=GO_REF:0000019, GO:0005689=PMID:15146077} O75533 Splicing factor 3B subunit 1 protein 20130213 {GO:0008380=TAS, GO:0010467=TAS, GO:0016607=IEA, GO:0000398=TAS, GO:0000375=NAS, GO:0003682=IEA, GO:0005654=TAS, GO:0005634=IDA, GO:0005681=NAS, GO:0071013=IDA, GO:0009952=IEA, GO:0005689=IDA} RNA splicing, RNA splicing, via transesterification reactions, anterior/posterior pattern specification, gene expression, mRNA splicing, via spliceosome U12-type spliceosomal complex, catalytic step 2 spliceosome, nuclear speck, nucleoplasm, nucleus, spliceosomal complex chromatin binding Human SF3B2 HPA UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0006397=PMID:8566756, GO:0010467=Reactome:REACT_71, GO:0000398=Reactome:REACT_1753, GO:0019048=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005654=Reactome:REACT_2241, GO:0005681=PMID:9731529, GO:0005634=GO_REF:0000052, GO:0071013=PMID:11991638, GO:0003676=GO_REF:0000002, GO:0005689=PMID:15146077} Q13435 Splicing factor 3B subunit 2 protein 20111111 {GO:0008380=TAS, GO:0006397=TAS, GO:0010467=TAS, GO:0000398=TAS, GO:0019048=IEA, GO:0005730=IDA, GO:0005654=TAS, GO:0005681=IDA, GO:0005634=IDA, GO:0071013=IDA, GO:0003676=IEA, GO:0005689=IDA} RNA splicing, gene expression, mRNA processing, mRNA splicing, via spliceosome, virus-host interaction U12-type spliceosomal complex, catalytic step 2 spliceosome, nucleolus, nucleoplasm, nucleus, spliceosomal complex nucleic acid binding NOT Human SF3B3 Reactome UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0006397=PMID:10490618, GO:0010467=Reactome:REACT_71, GO:0006461=PMID:10490618, GO:0000398=Reactome:REACT_1753, GO:0000375=PMID:10490618, GO:0030532=PMID:10490618, GO:0005654=Reactome:REACT_2241, GO:0005681=PMID:10490618, GO:0071013=PMID:11991638, GO:0003676=GO_REF:0000002, GO:0005689=PMID:15146077} Q15393 Splicing factor 3B subunit 3 protein 20130213 {GO:0008380=TAS, GO:0006397=TAS, GO:0010467=TAS, GO:0006461=TAS, GO:0000398=TAS, GO:0000375=TAS, GO:0030532=TAS, GO:0005654=TAS, GO:0005681=TAS, GO:0071013=IDA, GO:0003676=IEA, GO:0005689=IDA} RNA splicing, RNA splicing, via transesterification reactions, gene expression, mRNA processing, mRNA splicing, via spliceosome, protein complex assembly U12-type spliceosomal complex, catalytic step 2 spliceosome, nucleoplasm, small nuclear ribonucleoprotein complex, spliceosomal complex nucleic acid binding Human SF3B4 InterPro UniProtKB {GO:0005515=PMID:21988832, GO:0008380=Reactome:REACT_1735, GO:0006397=PMID:7958871, GO:0010467=Reactome:REACT_71, GO:0000166=GO_REF:0000002, GO:0000398=Reactome:REACT_1753, GO:0000375=PMID:7958871, GO:0003723=GO_REF:0000037, GO:0005654=Reactome:REACT_2241, GO:0005681=PMID:9731529, GO:0003676=GO_REF:0000002, GO:0005689=PMID:15146077} Q5SZ64 Splicing factor 3b, subunit 4, 49kDa protein 20130413 {GO:0005515=IPI, GO:0008380=TAS, GO:0006397=TAS, GO:0010467=TAS, GO:0000166=IEA, GO:0000398=TAS, GO:0000375=TAS, GO:0003723=IEA, GO:0005654=TAS, GO:0005681=IDA, GO:0003676=IEA, GO:0005689=IDA} RNA splicing, RNA splicing, via transesterification reactions, gene expression, mRNA processing, mRNA splicing, via spliceosome U12-type spliceosomal complex, nucleoplasm, spliceosomal complex RNA binding, nucleic acid binding, nucleotide binding, protein binding Human InterPro:IPR000504 SF3B5 Reactome UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0000398=Reactome:REACT_1753, GO:0005654=Reactome:REACT_2241, GO:0005634=GO_REF:0000054, GO:0005689=PMID:15146077} Q9BWJ5 Splicing factor 3B subunit 5 protein 20130213 {GO:0008380=TAS, GO:0010467=TAS, GO:0000398=TAS, GO:0005654=TAS, GO:0005634=IDA, GO:0005689=IDA} RNA splicing, gene expression, mRNA splicing, via spliceosome U12-type spliceosomal complex, nucleoplasm, nucleus Human SFI1 IntAct UniProtKB {GO:0005515=PMID:19389623, GO:0019902=PMID:19389623, GO:0005814=GO_REF:0000039, GO:0000086=Reactome:REACT_2203, GO:0010923=PMID:19389623, GO:0000278=Reactome:REACT_152, GO:0005829=Reactome:REACT_15470} A8K8P3 Protein SFI1 homolog protein 20130415 {GO:0005515=IPI, GO:0019902=IDA, GO:0005814=IEA, GO:0000086=TAS, GO:0010923=IDA, GO:0000278=TAS, GO:0005829=TAS} G2/M transition of mitotic cell cycle, mitotic cell cycle, negative regulation of phosphatase activity centriole, cytosol phosphatase binding, protein binding Human UniProtKB:P62136 SFMBT1 InterPro UniProtKB {GO:0006355=GO_REF:0000002, GO:0005634=GO_REF:0000002} Q9UHJ3 Scm-like with four MBT domains protein 1 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA} regulation of transcription, DNA-dependent nucleus Human InterPro:IPR004092 SFN HPA UniProtKB {GO:0005515=PMID:21625211, GO:0051219=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0030307=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0001836=PMID:11574543, GO:0000079=GO_REF:0000019, GO:0005615=PMID:8515476, GO:0005829=Reactome:REACT_147700, GO:0046827=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:1900740=Reactome:REACT_697, GO:0043154=PMID:11574543, GO:0030659=Reactome:REACT_147698, GO:0019901=GO_REF:0000019, GO:0008630=PMID:11574543, GO:0019904=GO_REF:0000002, GO:0006915=Reactome:REACT_578, GO:0043616=GO_REF:0000019, GO:0097193=Reactome:REACT_964, GO:0007165=PMID:8515476, GO:0030216=GO_REF:0000019, GO:0008426=PMID:8515476, GO:0043588=GO_REF:0000019, GO:0006469=PMID:8515476, GO:0016044=Reactome:REACT_11123} P31947 14-3-3 protein sigma protein 20081203 {GO:0005515=IPI, GO:0051219=IEA, GO:0008285=IEA, GO:0030307=IEA, GO:0005634=IEA, GO:0001836=IDA, GO:0000079=IEA, GO:0005615=TAS, GO:0005829=TAS, GO:0046827=IEA, GO:0005737=IDA, GO:1900740=TAS, GO:0043154=IDA, GO:0030659=TAS, GO:0019901=IEA, GO:0008630=IDA, GO:0019904=IEA, GO:0006915=TAS, GO:0043616=IEA, GO:0097193=TAS, GO:0007165=TAS, GO:0030216=IEA, GO:0008426=TAS, GO:0043588=IEA, GO:0006469=TAS, GO:0016044=TAS} apoptotic process, cellular membrane organization, intrinsic apoptotic signaling pathway, intrinsic apoptotic signaling pathway in response to DNA damage, keratinocyte differentiation, keratinocyte proliferation, negative regulation of cell proliferation, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of protein kinase activity, positive regulation of cell growth, positive regulation of protein export from nucleus, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, regulation of cyclin-dependent protein serine/threonine kinase activity, release of cytochrome c from mitochondria, signal transduction, skin development cytoplasm, cytoplasmic vesicle membrane, cytosol, extracellular space, nucleus phosphoprotein binding, protein binding, protein domain specific binding, protein kinase C inhibitor activity, protein kinase binding Human SFPQ BHF-UCL UniProtKB {GO:0005515=PMID:19874820, GO:0008380=PMID:8449401, GO:0006397=PMID:8449401, GO:0003723=GO_REF:0000037, GO:0006310=GO_REF:0000037, GO:0000122=PMID:22783022, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0016363=PMID:19874820, GO:0005737=GO_REF:0000039, GO:0006281=GO_REF:0000037, GO:0042382=PMID:19874820, GO:0000166=GO_REF:0000002, GO:0000380=PMID:19874820, GO:0005654=PMID:19874820} P23246 Splicing factor, proline- and glutamine-rich protein 20121121 {GO:0005515=IPI, GO:0008380=TAS, GO:0006397=TAS, GO:0003723=IEA, GO:0006310=IEA, GO:0000122=IMP, GO:0003677=IEA, GO:0006351=IEA, GO:0016363=IDA, GO:0005737=IEA, GO:0006281=IEA, GO:0042382=IDA, GO:0000166=IEA, GO:0000380=IMP, GO:0005654=IDA} DNA recombination, DNA repair, RNA splicing, alternative mRNA splicing, via spliceosome, mRNA processing, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, nuclear matrix, nucleoplasm, paraspeckles DNA binding, RNA binding, nucleotide binding, protein binding Human SFR1 UniProtKB UniProtKB {GO:0005515=PMID:21252223, GO:0032798=PMID:21252223, GO:0000724=PMID:21252223, GO:0005634=GO_REF:0000024} Q86XK3 Swi5-dependent recombination DNA repair protein 1 homolog protein 20110222 {GO:0005515=IPI, GO:0032798=IDA, GO:0000724=IMP, GO:0005634=ISS} double-strand break repair via homologous recombination Swi5-Sfr1 complex, nucleus protein binding Human UniProtKB:Q8BP27 SFRP1 BHF-UCL UniProtKB {GO:0071773=PMID:16149051, GO:0030308=PMID:20208569, GO:0030307=PMID:16288033, GO:0090263=PMID:18941195, GO:0050732=PMID:10980594, GO:0071560=PMID:16149051, GO:0009790=GO_REF:0000033, GO:0042995=GO_REF:0000033, GO:0032855=GO_REF:0000024, GO:0005615=PMID:9192640, GO:0071305=PMID:16149051, GO:0005622=PMID:17500071, GO:0005109=PMID:10347172, GO:0014034=GO_REF:0000019, GO:0071392=PMID:11932307, GO:0046676=PMID:17994217, GO:0009986=PMID:9192640, GO:0071391=PMID:18941195, GO:0030165=GO_REF:0000033, GO:2000080=PMID:17994217, GO:0060346=GO_REF:0000019, GO:0051496=GO_REF:0000024, GO:0030178=PMID:10660608, GO:0048147=PMID:19734317, GO:0030177=PMID:10660608, GO:0010719=PMID:19095296, GO:0090244=GO_REF:0000019, GO:0071380=PMID:16149501, GO:0090246=GO_REF:0000019, GO:0005829=PMID:14581477, GO:0045880=PMID:17035233, GO:0008144=PMID:19072540, GO:0035019=GO_REF:0000019, GO:0060070=PMID:18787224, GO:0060527=GO_REF:0000019, GO:0009267=PMID:11932307, GO:0042813=GO_REF:0000033, GO:0042493=PMID:19072540, GO:0005578=PMID:9192640, GO:0071456=PMID:11932307, GO:0045671=GO_REF:0000019, GO:0005576=GO_REF:0000038, GO:2000117=PMID:14581477, GO:0044345=GO_REF:0000019, GO:0044344=PMID:17500071, GO:0004197=PMID:14581477, GO:0046851=PMID:19072540, GO:0045668=GO_REF:0000019, GO:0071363=PMID:17500071, GO:0071504=PMID:17500071, GO:0006309=PMID:14581477, GO:0008406=GO_REF:0000033, GO:0001657=GO_REF:0000019, GO:0014070=PMID:20208569, GO:0017147=PMID:10347172, GO:0033689=PMID:19072540, GO:0050680=PMID:19095296, GO:0010564=PMID:9724099, GO:0042802=PMID:10347172, GO:2000054=PMID:9192640, GO:2000052=PMID:19569235, GO:0071356=PMID:9391078, GO:0001944=GO_REF:0000033, GO:0050679=PMID:16288033, GO:0030336=PMID:10980594, GO:0060766=PMID:19277043, GO:0001843=GO_REF:0000019, GO:0048546=GO_REF:0000019, GO:0001649=PMID:16149051, GO:0060687=GO_REF:0000019, GO:2000041=GO_REF:0000019, GO:0007420=GO_REF:0000033, GO:0071347=PMID:16149051, GO:0045600=PMID:12055200, GO:0045893=PMID:19723665, GO:0045892=PMID:10660608, GO:0001954=GO_REF:0000024, GO:0045578=PMID:18941195, GO:0008284=PMID:10980594, GO:0008285=PMID:10347172, GO:0005886=GO_REF:0000024, GO:2000270=PMID:14581477, GO:0071481=GO_REF:0000019, GO:0051894=GO_REF:0000024, GO:0009950=PMID:9192640, GO:2000271=PMID:14581477, GO:0030514=GO_REF:0000019, GO:0030279=PMID:15677765, GO:0002244=PMID:19778523, GO:0022601=PMID:11932307, GO:0043508=GO_REF:0000019, GO:0008201=PMID:9192640, GO:0090090=PMID:10347172, GO:0043066=PMID:19723665, GO:0043065=PMID:16149051, GO:0090179=GO_REF:0000019, GO:0045765=GO_REF:0000024, GO:0060218=PMID:19778523, GO:0031012=PMID:10347172, GO:0008585=GO_REF:0000019, GO:0010629=PMID:10980594, GO:0008584=GO_REF:0000019} Q8N474 Secreted frizzled-related protein 1 protein 20100818 {GO:0071773=IEP, GO:0030308=IDA, GO:0030307=IDA, GO:0090263=IDA, GO:0050732=IDA, GO:0071560=IEP, GO:0009790=IBA, GO:0042995=IKR, GO:0032855=ISS, GO:0005615=IDA, GO:0071305=IEP, GO:0005622=IDA, GO:0005109=IPI, GO:0014034=IEA, GO:0071392=IEP, GO:0046676=IDA, GO:0009986=IDA, GO:0071391=IDA, GO:0030165=IBA, GO:2000080=IDA, GO:0060346=IEA, GO:0051496=ISS, GO:0030178=IDA, GO:0048147=IDA, GO:0030177=IDA, GO:0010719=IDA, GO:0090244=IEA, GO:0071380=IEP, GO:0090246=IEA, GO:0005829=IDA, GO:0045880=IMP, GO:0008144=IDA, GO:0035019=IEA, GO:0060070=IDA, GO:0060527=IEA, GO:0009267=IEP, GO:0042813=IBA, GO:0042493=IDA, GO:0005578=IDA, GO:0071456=IEP, GO:0045671=IEA, GO:0005576=IEA, GO:2000117=IMP, GO:0044345=IEA, GO:0044344=IDA, GO:0004197=IMP, GO:0046851=IMP, GO:0045668=IEA, GO:0071363=IDA, GO:0071504=IDA, GO:0006309=IDA, GO:0008406=IBA, GO:0001657=IEA, GO:0014070=IDA, GO:0017147=IPI, GO:0033689=IMP, GO:0050680=IDA, GO:0010564=IMP, GO:0042802=IPI, GO:2000054=IDA, GO:2000052=IDA, GO:0071356=IDA, GO:0001944=IBA, GO:0050679=IMP, GO:0030336=IDA, GO:0060766=IDA, GO:0001843=IEA, GO:0048546=IEA, GO:0001649=IEP, GO:0060687=IEA, GO:2000041=IEA, GO:0007420=IBA, GO:0071347=IEP, GO:0045600=IDA, GO:0045893=IMP, GO:0045892=IDA, GO:0001954=ISS, GO:0045578=IMP, GO:0008284=IDA, GO:0008285=IDA, GO:0005886=ISS, GO:2000270=IDA, GO:0071481=IEA, GO:0051894=ISS, GO:0009950=IDA, GO:2000271=IDA, GO:0030514=IEA, GO:0030279=IDA, GO:0002244=IDA, GO:0022601=IEP, GO:0043508=IEA, GO:0008201=IDA, GO:0090090=IDA, GO:0043066=IMP, GO:0043065=IMP, GO:0090179=IEA, GO:0045765=ISS, GO:0060218=IDA, GO:0031012=IDA, GO:0008585=IEA, GO:0010629=IDA, GO:0008584=IEA} Wnt receptor signaling pathway involved in somitogenesis, apoptotic DNA fragmentation, bone trabecula formation, brain development, canonical Wnt receptor signaling pathway, cellular response to BMP stimulus, cellular response to X-ray, cellular response to estradiol stimulus, cellular response to estrogen stimulus, cellular response to fibroblast growth factor stimulus, cellular response to growth factor stimulus, cellular response to heparin, cellular response to hypoxia, cellular response to interleukin-1, cellular response to prostaglandin E stimulus, cellular response to starvation, cellular response to transforming growth factor beta stimulus, cellular response to tumor necrosis factor, cellular response to vitamin D, convergent extension involved in somitogenesis, digestive tract morphogenesis, dorsal/ventral axis specification, embryo development, female gonad development, gonad development, hematopoietic progenitor cell differentiation, hematopoietic stem cell differentiation, male gonad development, menstrual cycle phase, negative regulation of B cell differentiation, negative regulation of BMP signaling pathway, negative regulation of JUN kinase activity, negative regulation of Wnt receptor signaling pathway, negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification, negative regulation of androgen receptor signaling pathway, negative regulation of apoptotic process, negative regulation of bone remodeling, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation, negative regulation of cell growth, negative regulation of cell migration, negative regulation of cell proliferation, negative regulation of cysteine-type endopeptidase activity, negative regulation of epithelial cell proliferation, negative regulation of epithelial to mesenchymal transition, negative regulation of fibroblast apoptotic process, negative regulation of fibroblast proliferation, negative regulation of gene expression, negative regulation of insulin secretion, negative regulation of ossification, negative regulation of osteoblast differentiation, negative regulation of osteoblast proliferation, negative regulation of osteoclast differentiation, negative regulation of peptidyl-tyrosine phosphorylation, negative regulation of planar cell polarity pathway involved in axis elongation, negative regulation of transcription, DNA-dependent, neural crest cell fate commitment, neural tube closure, osteoblast differentiation, planar cell polarity pathway involved in neural tube closure, positive regulation of Rac GTPase activity, positive regulation of Wnt receptor signaling pathway, positive regulation of apoptotic process, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of cell growth, positive regulation of cell proliferation, positive regulation of cell-matrix adhesion, positive regulation of epithelial cell proliferation, positive regulation of fat cell differentiation, positive regulation of fibroblast apoptotic process, positive regulation of focal adhesion assembly, positive regulation of non-canonical Wnt receptor signaling pathway, positive regulation of smoothened signaling pathway, positive regulation of stress fiber assembly, positive regulation of transcription, DNA-dependent, prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis, regulation of angiogenesis, regulation of branching involved in prostate gland morphogenesis, regulation of cell cycle process, response to drug, response to organic cyclic compound, somatic stem cell maintenance, stromal-epithelial cell signaling involved in prostate gland development, ureteric bud development, vasculature development cell projection, cell surface, cytosol, extracellular matrix, extracellular region, extracellular space, intracellular, plasma membrane, proteinaceous extracellular matrix PDZ domain binding, Wnt-activated receptor activity, Wnt-protein binding, cysteine-type endopeptidase activity, drug binding, frizzled binding, heparin binding, identical protein binding Human SFRP2 BHF-UCL UniProtKB {GO:0008406=GO_REF:0000033, GO:0017147=GO_REF:0000033, GO:0030308=PMID:20208569, GO:0030307=PMID:10980594, GO:0090263=GO_REF:0000024, GO:0050680=PMID:19095296, GO:0050732=PMID:10980594, GO:0042995=GO_REF:0000033, GO:0009790=GO_REF:0000033, GO:0005615=GO_REF:0000024, GO:0002063=GO_REF:0000019, GO:0030199=GO_REF:0000019, GO:0031668=GO_REF:0000019, GO:0010667=GO_REF:0000019, GO:0061185=GO_REF:0000024, GO:0048018=GO_REF:0000024, GO:0001944=GO_REF:0000033, GO:0030336=PMID:10980594, GO:0001843=GO_REF:0000019, GO:0030165=GO_REF:0000033, GO:0048546=GO_REF:0000019, GO:2000035=GO_REF:0000024, GO:2000041=GO_REF:0000019, GO:0071425=GO_REF:0000024, GO:0005178=GO_REF:0000024, GO:0007420=GO_REF:0000033, GO:0060349=GO_REF:0000019, GO:0061056=GO_REF:0000024, GO:0045600=PMID:12055200, GO:0045892=PMID:19095296, GO:0042733=GO_REF:0000019, GO:0008284=PMID:10980594, GO:0008285=PMID:17848950, GO:0005886=GO_REF:0000033, GO:0007267=GO_REF:0000024, GO:0042662=GO_REF:0000019, GO:0030178=PMID:20208569, GO:0071481=GO_REF:0000019, GO:0003214=PMID:19593212, GO:0010719=PMID:19095296, GO:0090244=GO_REF:0000019, GO:0035413=GO_REF:0000019, GO:0060028=GO_REF:0000019, GO:0030514=GO_REF:0000019, GO:0033138=GO_REF:0000024, GO:0005737=GO_REF:0000033, GO:0045944=GO_REF:0000024, GO:0001968=GO_REF:0000024, GO:0043508=GO_REF:0000019, GO:0043154=GO_REF:0000019, GO:0090090=PMID:17471511, GO:0042813=GO_REF:0000033, GO:0001569=GO_REF:0000024, GO:0043066=GO_REF:0000024, GO:0043065=PMID:17848950, GO:0042493=GO_REF:0000019, GO:0033630=GO_REF:0000024, GO:0090179=GO_REF:0000019, GO:0010577=GO_REF:0000019, GO:0045766=GO_REF:0000024, GO:0003151=PMID:19593212, GO:0036342=GO_REF:0000019, GO:0031012=GO_REF:0000024, GO:0045669=GO_REF:0000019, GO:0061133=GO_REF:0000019, GO:0010629=PMID:10980594, GO:0008584=GO_REF:0000019} Q96HF1 Secreted frizzled-related protein 2 protein 20100819 {GO:0008406=IBA, GO:0017147=IBA, GO:0030308=IDA, GO:0030307=ISS, GO:0090263=ISS, GO:0050680=IDA, GO:0050732=ISS, GO:0042995=IKR, GO:0009790=IBA, GO:0005615=ISS, GO:0002063=IEA, GO:0030199=IEA, GO:0031668=IEA, GO:0010667=IEA, GO:0061185=ISS, GO:0048018=ISS, GO:0001944=IBA, GO:0030336=ISS, GO:0001843=IEA, GO:0030165=IBA, GO:0048546=IEA, GO:2000035=ISS, GO:2000041=IEA, GO:0071425=ISS, GO:0005178=ISS, GO:0007420=IBA, GO:0060349=IEA, GO:0061056=ISS, GO:0045600=IDA, GO:0045892=IDA, GO:0042733=IEA, GO:0008284=IDA, GO:0008285=IMP, GO:0005886=IBA, GO:0007267=ISS, GO:0042662=IEA, GO:0030178=IDA, GO:0071481=IEA, GO:0003214=IMP, GO:0010719=IDA, GO:0090244=IEA, GO:0035413=IEA, GO:0060028=IEA, GO:0030514=IEA, GO:0033138=ISS, GO:0005737=IBA, GO:0045944=ISS, GO:0001968=ISS, GO:0043508=IEA, GO:0043154=IEA, GO:0090090=IDA, GO:0042813=IBA, GO:0001569=ISS, GO:0043066=ISS, GO:0043065=IMP, GO:0042493=IEA, GO:0033630=ISS, GO:0090179=IEA, GO:0010577=IEA, GO:0045766=ISS, GO:0003151=IMP, GO:0036342=IEA, GO:0031012=ISS, GO:0045669=IEA, GO:0061133=IEA, GO:0010629=ISS, GO:0008584=IEA} Wnt receptor signaling pathway involved in somitogenesis, bone morphogenesis, brain development, cardiac left ventricle morphogenesis, cell-cell signaling, cellular response to X-ray, cellular response to extracellular stimulus, chondrocyte development, collagen fibril organization, convergent extension involved in axis elongation, digestive tract morphogenesis, embryo development, embryonic digit morphogenesis, gonad development, hematopoietic stem cell proliferation, male gonad development, negative regulation of BMP signaling pathway, negative regulation of JUN kinase activity, negative regulation of Wnt receptor signaling pathway, negative regulation of apoptotic process, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cardiac muscle cell apoptotic process, negative regulation of cell growth, negative regulation of cell migration, negative regulation of cell proliferation, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of dermatome development, negative regulation of epithelial cell proliferation, negative regulation of epithelial to mesenchymal transition, negative regulation of gene expression, negative regulation of mesodermal cell fate specification, negative regulation of peptidyl-tyrosine phosphorylation, negative regulation of planar cell polarity pathway involved in axis elongation, negative regulation of transcription, DNA-dependent, neural tube closure, outflow tract morphogenesis, patterning of blood vessels, planar cell polarity pathway involved in neural tube closure, positive regulation of angiogenesis, positive regulation of apoptotic process, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of catenin import into nucleus, positive regulation of cell adhesion mediated by integrin, positive regulation of cell growth, positive regulation of cell proliferation, positive regulation of fat cell differentiation, positive regulation of osteoblast differentiation, positive regulation of peptidyl-serine phosphorylation, positive regulation of transcription from RNA polymerase II promoter, post-anal tail morphogenesis, regulation of stem cell division, response to drug, sclerotome development, vasculature development cell projection, cytoplasm, extracellular matrix, extracellular space, plasma membrane PDZ domain binding, Wnt-activated receptor activity, Wnt-protein binding, endopeptidase activator activity, fibronectin binding, integrin binding, metalloenzyme activator activity, receptor agonist activity Human SFSWAP PINC UniProtKB {GO:0006397=PMID:8940107, GO:0006396=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0048025=GO_REF:0000024, GO:0003723=GO_REF:0000037, GO:0006376=PMID:8940107, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q12872 Splicing factor, suppressor of white-apricot homolog protein 20030904 {GO:0006397=TAS, GO:0006396=IEA, GO:0006355=IEA, GO:0048025=ISS, GO:0003723=IEA, GO:0006376=TAS, GO:0005634=IEA, GO:0006351=IEA} RNA processing, mRNA processing, mRNA splice site selection, negative regulation of mRNA splicing, via spliceosome, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus RNA binding Human SFT2D1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0016192=GO_REF:0000002} Q8WV19 Vesicle transport protein SFT2A protein 20130413 {GO:0016021=IEA, GO:0015031=IEA, GO:0016192=IEA} protein transport, vesicle-mediated transport integral to membrane Human UniProtKB-KW:KW-0812 SFT2D2 InterPro UniProtKB {GO:0016021=GO_REF:0000002, GO:0015031=GO_REF:0000037, GO:0016192=GO_REF:0000002} Q5TIH2 Vesicle transport protein SFT2B protein 20130413 {GO:0016021=IEA, GO:0015031=IEA, GO:0016192=IEA} protein transport, vesicle-mediated transport integral to membrane Human InterPro:IPR007305 SFT2D3 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0016192=GO_REF:0000002} Q587I9 Vesicle transport protein SFT2C protein 20130413 {GO:0016021=IEA, GO:0015031=IEA, GO:0016192=IEA} protein transport, vesicle-mediated transport integral to membrane Human UniProtKB-KW:KW-0812 SFTPA1 GOC UniProtKB {GO:0005581=GO_REF:0000037, GO:0007585=GO_REF:0000037, GO:0006869=PMID:2995821, GO:0030246=GO_REF:0000002, GO:0005576=Reactome:REACT_23944, GO:0005615=GO_REF:0000039, GO:0005319=PMID:2995821} Q8IWL2 Pulmonary surfactant-associated protein A1 protein 20130413 {GO:0005581=IEA, GO:0007585=IEA, GO:0006869=TAS, GO:0030246=IEA, GO:0005576=TAS, GO:0005615=IEA, GO:0005319=TAS} lipid transport, respiratory gaseous exchange collagen, extracellular region, extracellular space carbohydrate binding, lipid transporter activity Human SFTPA2 Reactome UniProtKB {GO:0005581=GO_REF:0000037, GO:0007585=GO_REF:0000037, GO:0030246=GO_REF:0000002, GO:0005576=Reactome:REACT_23944, GO:0005615=GO_REF:0000039} Q8IWL1 Pulmonary surfactant-associated protein A2 protein 20090212 {GO:0005581=IEA, GO:0007585=IEA, GO:0030246=IEA, GO:0005576=TAS, GO:0005615=IEA} respiratory gaseous exchange collagen, extracellular region, extracellular space carbohydrate binding Human SFTPB PINC UniProtKB {GO:0006665=GO_REF:0000002, GO:0007585=GO_REF:0000037, GO:0009887=PMID:10378403, GO:0005615=GO_REF:0000039, GO:0005764=GO_REF:0000002} P07988 Pulmonary surfactant-associated protein B protein 20031120 {GO:0006665=IEA, GO:0007585=IEA, GO:0009887=TAS, GO:0005615=IEA, GO:0005764=IEA} organ morphogenesis, respiratory gaseous exchange, sphingolipid metabolic process extracellular space, lysosome Human SFTPC UniProtKB UniProtKB {GO:0005515=PMID:19815549, GO:0071732=GO_REF:0000019, GO:0007585=GO_REF:0000037, GO:0097208=GO_REF:0000019, GO:0005771=GO_REF:0000019, GO:0033189=GO_REF:0000019, GO:0005576=GO_REF:0000002, GO:0051384=GO_REF:0000019, GO:0070848=GO_REF:0000019, GO:0005615=GO_REF:0000039, GO:0051591=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0009749=GO_REF:0000019, GO:0055093=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0070741=GO_REF:0000019, GO:0007623=GO_REF:0000019, GO:0051260=GO_REF:0000019, GO:0032526=GO_REF:0000019, GO:0071260=GO_REF:0000019} P11686 Pulmonary surfactant-associated protein C protein 20120708 {GO:0005515=IPI, GO:0071732=IEA, GO:0007585=IEA, GO:0097208=IEA, GO:0005771=IEA, GO:0033189=IEA, GO:0005576=IEA, GO:0051384=IEA, GO:0070848=IEA, GO:0005615=IEA, GO:0051591=IEA, GO:0042803=IEA, GO:0009749=IEA, GO:0055093=IEA, GO:0032496=IEA, GO:0070741=IEA, GO:0007623=IEA, GO:0051260=IEA, GO:0032526=IEA, GO:0071260=IEA} cellular response to mechanical stimulus, cellular response to nitric oxide, circadian rhythm, protein homooligomerization, respiratory gaseous exchange, response to cAMP, response to glucocorticoid stimulus, response to glucose stimulus, response to growth factor stimulus, response to hyperoxia, response to interleukin-6, response to lipopolysaccharide, response to retinoic acid, response to vitamin A alveolar lamellar body, extracellular region, extracellular space, multivesicular body protein binding, protein homodimerization activity Human UniProtKB:Q5HYA8 SFTPD Reactome UniProtKB {GO:0005515=PMID:12884308, GO:0005581=GO_REF:0000037, GO:0007585=GO_REF:0000037, GO:0048286=PMID:9751757, GO:0072593=PMID:10485905, GO:0005576=Reactome:REACT_23944, GO:0030139=PMID:10485905, GO:0001817=PMID:9751757, GO:0005615=GO_REF:0000039, GO:0005764=PMID:10485905, GO:0006898=PMID:10485905, GO:0042130=PMID:10485905, GO:0045085=PMID:10485905, GO:0051635=PMID:9751757, GO:0050766=PMID:10485905, GO:0045087=PMID:10485905, GO:0030246=PMID:10485905, GO:0043129=PMID:9751757, GO:0048246=PMID:10485905} P35247 Pulmonary surfactant-associated protein D protein 20090212 {GO:0005515=IPI, GO:0005581=IEA, GO:0007585=IEA, GO:0048286=IMP, GO:0072593=TAS, GO:0005576=TAS, GO:0030139=TAS, GO:0001817=NAS, GO:0005615=IEA, GO:0005764=TAS, GO:0006898=TAS, GO:0042130=TAS, GO:0045085=TAS, GO:0051635=TAS, GO:0050766=TAS, GO:0045087=TAS, GO:0030246=TAS, GO:0043129=IMP, GO:0048246=TAS} innate immune response, lung alveolus development, macrophage chemotaxis, negative regulation of T cell proliferation, negative regulation of interleukin-2 biosynthetic process, positive regulation of phagocytosis, reactive oxygen species metabolic process, receptor-mediated endocytosis, regulation of cytokine production, respiratory gaseous exchange, surfactant homeostasis collagen, endocytic vesicle, extracellular region, extracellular space, lysosome bacterial cell surface binding, carbohydrate binding, protein binding Human SFXN1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0016020=GO_REF:0000002, GO:0030218=GO_REF:0000019, GO:0008324=GO_REF:0000002, GO:0005743=GO_REF:0000019, GO:0006826=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0055072=GO_REF:0000037} Q9H9B4 Sideroflexin-1 protein 20100326 {GO:0005739=IDA, GO:0016020=IEA, GO:0030218=IEA, GO:0008324=IEA, GO:0005743=IEA, GO:0006826=IEA, GO:0016021=IEA, GO:0055072=IEA} erythrocyte differentiation, iron ion homeostasis, iron ion transport integral to membrane, membrane, mitochondrial inner membrane, mitochondrion cation transmembrane transporter activity Human SFXN2 ENSEMBL UniProtKB {GO:0008324=GO_REF:0000002, GO:0005743=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0055072=GO_REF:0000037} Q96NB2 Sideroflexin-2 protein 20130413 {GO:0008324=IEA, GO:0005743=IEA, GO:0016021=IEA, GO:0055072=IEA} iron ion homeostasis integral to membrane, mitochondrial inner membrane cation transmembrane transporter activity Human Ensembl:ENSMUSP00000026011 SFXN3 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0031966=GO_REF:0000039, GO:0008324=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0055072=GO_REF:0000037} Q9BWM7 Sideroflexin-3 protein 20080205 {GO:0005739=IDA, GO:0031966=IEA, GO:0008324=IEA, GO:0016021=IEA, GO:0055072=IEA} iron ion homeostasis integral to membrane, mitochondrial membrane, mitochondrion cation transmembrane transporter activity Human SFXN4 HPA UniProtKB {GO:0031966=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0008324=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0055072=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q6P4A7 Sideroflexin-4 protein 20101115 {GO:0031966=IEA, GO:0016020=IEA, GO:0008324=IEA, GO:0016021=IEA, GO:0055072=IEA, GO:0043231=IDA} iron ion homeostasis integral to membrane, intracellular membrane-bounded organelle, membrane, mitochondrial membrane cation transmembrane transporter activity Human SGCA PINC UniProtKB {GO:0042383=GO_REF:0000039, GO:0005737=GO_REF:0000037, GO:0007517=PMID:7663524, GO:0006936=PMID:8069911, GO:0016010=PMID:7937874, GO:0005911=GO_REF:0000019, GO:0016012=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0045121=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0005856=GO_REF:0000039} Q16586 Alpha-sarcoglycan protein 20030904 {GO:0042383=IEA, GO:0005737=IEA, GO:0007517=TAS, GO:0006936=TAS, GO:0016010=TAS, GO:0005911=IEA, GO:0016012=IEA, GO:0005509=IEA, GO:0045121=IEA, GO:0016021=IEA, GO:0005856=IEA} muscle contraction, muscle organ development cell-cell junction, cytoplasm, cytoskeleton, dystrophin-associated glycoprotein complex, integral to membrane, membrane raft, sarcoglycan complex, sarcolemma calcium ion binding Human SGCB PINC UniProtKB {GO:0042383=GO_REF:0000039, GO:0005737=GO_REF:0000037, GO:0007517=PMID:8968749, GO:0016010=PMID:17993586, GO:0005887=PMID:7581448, GO:0016012=GO_REF:0000002, GO:0007010=GO_REF:0000002, GO:0035051=GO_REF:0000019, GO:0016021=GO_REF:0000002, GO:0005856=GO_REF:0000039} Q16585 Beta-sarcoglycan protein 20030904 {GO:0042383=IEA, GO:0005737=IEA, GO:0007517=TAS, GO:0016010=IDA, GO:0005887=TAS, GO:0016012=IEA, GO:0007010=IEA, GO:0035051=IEA, GO:0016021=IEA, GO:0005856=IEA} cardiocyte differentiation, cytoskeleton organization, muscle organ development cytoplasm, cytoskeleton, dystrophin-associated glycoprotein complex, integral to membrane, integral to plasma membrane, sarcoglycan complex, sarcolemma Human SGCD PINC UniProtKB {GO:0042383=GO_REF:0000039, GO:0005737=GO_REF:0000037, GO:0007517=PMID:8842738, GO:0005886=PMID:8842738, GO:0016010=PMID:17993586, GO:0016012=GO_REF:0000019, GO:0007010=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005856=GO_REF:0000039} Q92629 Delta-sarcoglycan protein 20030904 {GO:0042383=IEA, GO:0005737=IEA, GO:0007517=TAS, GO:0005886=TAS, GO:0016010=IDA, GO:0016012=IEA, GO:0007010=IEA, GO:0016021=IEA, GO:0005856=IEA} cytoskeleton organization, muscle organ development cytoplasm, cytoskeleton, dystrophin-associated glycoprotein complex, integral to membrane, plasma membrane, sarcoglycan complex, sarcolemma Human SGCE PINC UniProtKB {GO:0042383=GO_REF:0000039, GO:0005737=GO_REF:0000037, GO:0007517=PMID:9405466, GO:0007160=PMID:9405466, GO:0016010=PMID:17993586, GO:0005887=PMID:9475163, GO:0016012=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0005856=GO_REF:0000039} O43556 Epsilon-sarcoglycan protein 20030904 {GO:0042383=IEA, GO:0005737=IEA, GO:0007517=TAS, GO:0007160=TAS, GO:0016010=IDA, GO:0005887=TAS, GO:0016012=IEA, GO:0005509=IEA, GO:0005856=IEA} cell-matrix adhesion, muscle organ development cytoplasm, cytoskeleton, dystrophin-associated glycoprotein complex, integral to plasma membrane, sarcoglycan complex, sarcolemma calcium ion binding Human SGCG PINC UniProtKB {GO:0042383=GO_REF:0000039, GO:0005737=GO_REF:0000037, GO:0007517=PMID:8641426, GO:0005886=PMID:8641426, GO:0016012=GO_REF:0000019, GO:0007010=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005856=GO_REF:0000039} Q13326 Gamma-sarcoglycan protein 20030904 {GO:0042383=IEA, GO:0005737=IEA, GO:0007517=TAS, GO:0005886=TAS, GO:0016012=IEA, GO:0007010=IEA, GO:0016021=IEA, GO:0005856=IEA} cytoskeleton organization, muscle organ development cytoplasm, cytoskeleton, integral to membrane, plasma membrane, sarcoglycan complex, sarcolemma Human SGCZ BHF-UCL UniProtKB {GO:0042383=GO_REF:0000039, GO:0005737=GO_REF:0000037, GO:0016012=PMID:17438352, GO:0007010=GO_REF:0000002, GO:0055001=PMID:17438352, GO:0016021=GO_REF:0000037, GO:0005856=GO_REF:0000039, GO:0046716=PMID:17438352, GO:0016044=PMID:17438352} Q96LD1 Zeta-sarcoglycan protein 20110819 {GO:0042383=IEA, GO:0005737=IEA, GO:0016012=TAS, GO:0007010=IEA, GO:0055001=TAS, GO:0016021=IEA, GO:0005856=IEA, GO:0046716=TAS, GO:0016044=TAS} cellular membrane organization, cytoskeleton organization, muscle cell development, muscle cell homeostasis cytoplasm, cytoskeleton, integral to membrane, sarcoglycan complex, sarcolemma Human SGIP1 LIFEdb UniProtKB {GO:0008017=GO_REF:0000024, GO:0005515=PMID:15919751, GO:0017124=PMID:20946875, GO:0005886=PMID:20946875, GO:0030122=GO_REF:0000024, GO:0030136=GO_REF:0000024, GO:0002021=GO_REF:0000024, GO:0006897=GO_REF:0000037, GO:2000253=GO_REF:0000024, GO:0005737=GO_REF:0000054, GO:0005905=PMID:20946875, GO:0005543=GO_REF:0000024, GO:0048260=GO_REF:0000024, GO:2000507=GO_REF:0000024} Q9BQI5 SH3-containing GRB2-like protein 3-interacting protein 1 protein 20100607 {GO:0008017=ISS, GO:0005515=IPI, GO:0017124=IPI, GO:0005886=IDA, GO:0030122=ISS, GO:0030136=ISS, GO:0002021=ISS, GO:0006897=IEA, GO:2000253=ISS, GO:0005737=IDA, GO:0005905=IDA, GO:0005543=ISS, GO:0048260=ISS, GO:2000507=ISS} endocytosis, positive regulation of energy homeostasis, positive regulation of feeding behavior, positive regulation of receptor-mediated endocytosis, response to dietary excess AP-2 adaptor complex, clathrin-coated vesicle, coated pit, cytoplasm, plasma membrane SH3 domain binding, microtubule binding, phospholipid binding, protein binding Human SGK1 Reactome UniProtKB {GO:0005886=GO_REF:0000039, GO:0015459=PMID:20530112, GO:0032411=PMID:20530112, GO:0005634=GO_REF:0000039, GO:0001558=PMID:20919962, GO:0070294=PMID:16460280, GO:0005829=Reactome:REACT_160256, GO:0005739=GO_REF:0000039, GO:0051090=PMID:20530112, GO:0034220=Reactome:REACT_25300, GO:0007154=GO_REF:0000002, GO:0042127=PMID:20530112, GO:0060453=PMID:20530112, GO:0006814=PMID:10884438, GO:0030334=PMID:20919962, GO:0007616=PMID:20530112, GO:0005246=PMID:20530112, GO:0006950=PMID:9114008, GO:0006915=GO_REF:0000037, GO:0042981=PMID:20530112, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0006974=GO_REF:0000019, GO:0050790=PMID:20530112, GO:0004672=GO_REF:0000019, GO:0004674=GO_REF:0000037, GO:0008217=PMID:16460280, GO:0005789=GO_REF:0000039, GO:0006468=PMID:9114008, GO:0035091=GO_REF:0000002, GO:0017081=PMID:20530112, GO:0017080=PMID:20530112} O00141 Serine/threonine-protein kinase Sgk1 protein 20130301 {GO:0005886=IEA, GO:0015459=TAS, GO:0032411=TAS, GO:0005634=IEA, GO:0001558=TAS, GO:0070294=TAS, GO:0005829=TAS, GO:0005739=IEA, GO:0051090=TAS, GO:0034220=TAS, GO:0007154=IEA, GO:0042127=TAS, GO:0060453=TAS, GO:0006814=TAS, GO:0030334=TAS, GO:0007616=TAS, GO:0005246=TAS, GO:0006950=TAS, GO:0006915=IEA, GO:0042981=TAS, GO:0055085=TAS, GO:0005524=IEA, GO:0006974=IEA, GO:0050790=TAS, GO:0004672=IEA, GO:0004674=IEA, GO:0008217=TAS, GO:0005789=IEA, GO:0006468=TAS, GO:0035091=IEA, GO:0017081=TAS, GO:0017080=TAS} apoptotic process, cell communication, ion transmembrane transport, long-term memory, positive regulation of transporter activity, protein phosphorylation, regulation of apoptotic process, regulation of blood pressure, regulation of catalytic activity, regulation of cell growth, regulation of cell migration, regulation of cell proliferation, regulation of gastric acid secretion, regulation of sequence-specific DNA binding transcription factor activity, renal sodium ion absorption, response to DNA damage stimulus, response to stress, sodium ion transport, transmembrane transport cytosol, endoplasmic reticulum membrane, mitochondrion, nucleus, plasma membrane ATP binding, calcium channel regulator activity, chloride channel regulator activity, phosphatidylinositol binding, potassium channel regulator activity, protein kinase activity, protein serine/threonine kinase activity, sodium channel regulator activity Human SGK2 Reactome UniProtKB {GO:0015459=PMID:12397388, GO:0032411=PMID:16460280, GO:0005634=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0055085=Reactome:REACT_15518, GO:0005524=GO_REF:0000037, GO:0001558=PMID:20919962, GO:0007243=PMID:10548550, GO:0005829=Reactome:REACT_160256, GO:0034220=Reactome:REACT_25300, GO:0004674=GO_REF:0000037, GO:0042127=PMID:20919962, GO:0006468=PMID:12397388, GO:0006979=PMID:10548550, GO:0017080=PMID:16460280} Q9HBY8 Serine/threonine-protein kinase Sgk2 protein 20130301 {GO:0015459=IDA, GO:0032411=TAS, GO:0005634=IEA, GO:0005575=ND, GO:0055085=TAS, GO:0005524=IEA, GO:0001558=TAS, GO:0007243=TAS, GO:0005829=TAS, GO:0034220=TAS, GO:0004674=IEA, GO:0042127=TAS, GO:0006468=NAS, GO:0006979=TAS, GO:0017080=TAS} intracellular protein kinase cascade, ion transmembrane transport, positive regulation of transporter activity, protein phosphorylation, regulation of cell growth, regulation of cell proliferation, response to oxidative stress, transmembrane transport cellular_component, cytosol, nucleus ATP binding, potassium channel regulator activity, protein serine/threonine kinase activity, sodium channel regulator activity Human SGK3 Reactome UniProtKB {GO:0030334=PMID:20919962, GO:0043066=GO_REF:0000019, GO:0005246=PMID:16460280, GO:0006950=PMID:10548550, GO:0015459=PMID:16460280, GO:0055085=Reactome:REACT_15518, GO:0001558=PMID:20919962, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_160256, GO:0051090=PMID:20919962, GO:0034220=Reactome:REACT_25300, GO:0007154=GO_REF:0000002, GO:0004672=PMID:10585774, GO:0004674=GO_REF:0000019, GO:0042127=PMID:20919962, GO:0016023=GO_REF:0000039, GO:0006468=PMID:10548550, GO:0035091=GO_REF:0000002, GO:0055037=GO_REF:0000039, GO:0017081=PMID:16460280, GO:0005769=GO_REF:0000039, GO:0017080=PMID:16460280} Q96BR1 Serine/threonine-protein kinase Sgk3 protein 20130301 {GO:0030334=TAS, GO:0043066=IEA, GO:0005246=TAS, GO:0006950=TAS, GO:0015459=TAS, GO:0055085=TAS, GO:0001558=TAS, GO:0005524=IEA, GO:0005829=TAS, GO:0051090=TAS, GO:0034220=TAS, GO:0007154=IEA, GO:0004672=TAS, GO:0004674=IEA, GO:0042127=TAS, GO:0016023=IEA, GO:0006468=TAS, GO:0035091=IEA, GO:0055037=IEA, GO:0017081=TAS, GO:0005769=IEA, GO:0017080=TAS} cell communication, ion transmembrane transport, negative regulation of apoptotic process, protein phosphorylation, regulation of cell growth, regulation of cell migration, regulation of cell proliferation, regulation of sequence-specific DNA binding transcription factor activity, response to stress, transmembrane transport cytoplasmic membrane-bounded vesicle, cytosol, early endosome, recycling endosome ATP binding, calcium channel regulator activity, chloride channel regulator activity, phosphatidylinositol binding, potassium channel regulator activity, protein kinase activity, protein serine/threonine kinase activity, sodium channel regulator activity Human SGMS1 Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0033188=PMID:14976195, GO:0005886=PMID:14976195, GO:0006686=PMID:14976195, GO:0005783=PMID:14976195, GO:0030148=Reactome:REACT_115810, GO:0006915=GO_REF:0000037, GO:0005634=PMID:14976195, GO:0044281=Reactome:REACT_111217, GO:0047493=PMID:14685263, GO:0030173=PMID:14685263, GO:0000139=Reactome:REACT_19414, GO:0016301=GO_REF:0000037, GO:0000138=PMID:14685263, GO:0016049=PMID:14976195, GO:0016740=GO_REF:0000038} Q86VZ5 Phosphatidylcholine:ceramide cholinephosphotransferase 1 protein 20130301 {GO:0006665=TAS, GO:0033188=IMP, GO:0005886=TAS, GO:0006686=IDA, GO:0005783=TAS, GO:0030148=TAS, GO:0006915=IEA, GO:0005634=TAS, GO:0044281=TAS, GO:0047493=IDA, GO:0030173=IDA, GO:0000139=TAS, GO:0016301=IEA, GO:0000138=IDA, GO:0016049=IDA, GO:0016740=IEA} apoptotic process, cell growth, small molecule metabolic process, sphingolipid biosynthetic process, sphingolipid metabolic process, sphingomyelin biosynthetic process Golgi membrane, Golgi trans cisterna, endoplasmic reticulum, integral to Golgi membrane, nucleus, plasma membrane ceramide cholinephosphotransferase activity, kinase activity, sphingomyelin synthase activity, transferase activity Human SGMS2 Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0047493=PMID:14685263, GO:0033188=GO_REF:0000003, GO:0030173=PMID:14685263, GO:0005794=PMID:14685263, GO:0005886=Reactome:REACT_19278, GO:0005887=PMID:14685263, GO:0006686=PMID:14685263, GO:0016301=GO_REF:0000037, GO:0030148=Reactome:REACT_115810, GO:0045203=GO_REF:0000019, GO:0044281=Reactome:REACT_111217} Q8NHU3 Phosphatidylcholine:ceramide cholinephosphotransferase 2 protein 20130301 {GO:0006665=TAS, GO:0047493=IDA, GO:0033188=IEA, GO:0030173=IDA, GO:0005794=IDA, GO:0005886=TAS, GO:0005887=IDA, GO:0006686=IDA, GO:0016301=IEA, GO:0030148=TAS, GO:0045203=IEA, GO:0044281=TAS} small molecule metabolic process, sphingolipid biosynthetic process, sphingolipid metabolic process, sphingomyelin biosynthetic process Golgi apparatus, integral to Golgi membrane, integral to cell outer membrane, integral to plasma membrane, plasma membrane ceramide cholinephosphotransferase activity, kinase activity, sphingomyelin synthase activity Human SGOL1 Reactome UniProtKB {GO:0005515=PMID:16580887, GO:0000236=Reactome:REACT_682, GO:0000780=GO_REF:0000019, GO:0005813=PMID:18331714, GO:0010457=PMID:18331714, GO:0030892=PMID:18084284, GO:0005829=Reactome:REACT_150414, GO:0000922=PMID:18331714, GO:0007059=PMID:16580887, GO:0045132=GO_REF:0000002, GO:0000087=Reactome:REACT_910, GO:0000777=GO_REF:0000039, GO:0000776=PMID:16582621, GO:0000779=PMID:19465021, GO:0000278=Reactome:REACT_152, GO:0008608=PMID:17621308, GO:0000090=Reactome:REACT_1275, GO:0000775=PMID:16682347, GO:0051301=GO_REF:0000037} Q5FBB7 Shugoshin-like 1 protein 20111007 {GO:0005515=IPI, GO:0000236=TAS, GO:0000780=IEA, GO:0005813=IDA, GO:0010457=IDA, GO:0030892=IDA, GO:0005829=TAS, GO:0000922=IDA, GO:0007059=IDA, GO:0045132=IEA, GO:0000087=TAS, GO:0000777=IEA, GO:0000776=IDA, GO:0000779=IDA, GO:0000278=TAS, GO:0008608=IDA, GO:0000090=TAS, GO:0000775=IDA, GO:0051301=IEA} M phase of mitotic cell cycle, attachment of spindle microtubules to kinetochore, cell division, centriole-centriole cohesion, chromosome segregation, meiotic chromosome segregation, mitotic anaphase, mitotic cell cycle, mitotic prometaphase centrosome, chromosome, centromeric region, condensed chromosome kinetochore, condensed chromosome, centromeric region, condensed nuclear chromosome, centromeric region, cytosol, kinetochore, mitotic cohesin complex, spindle pole protein binding Human SGOL2 HPA UniProtKB {GO:0005515=PMID:17485487, GO:0000236=Reactome:REACT_682, GO:0030892=PMID:18084284, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005829=Reactome:REACT_150414, GO:0000087=Reactome:REACT_910, GO:0000777=GO_REF:0000039, GO:0051754=GO_REF:0000002, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0000775=PMID:17485487, GO:0051301=GO_REF:0000037} Q562F6 Shugoshin-like 2 protein 20101115 {GO:0005515=IPI, GO:0000236=TAS, GO:0030892=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0005829=TAS, GO:0000087=TAS, GO:0000777=IEA, GO:0051754=IEA, GO:0000278=TAS, GO:0000090=TAS, GO:0000775=IDA, GO:0051301=IEA} M phase of mitotic cell cycle, cell division, meiotic sister chromatid cohesion, centromeric, mitotic anaphase, mitotic cell cycle, mitotic prometaphase chromosome, centromeric region, condensed chromosome kinetochore, cytosol, mitotic cohesin complex, nucleolus, nucleus protein binding NOT Human SGPL1 HPA UniProtKB {GO:0005515=PMID:21903422, GO:0005783=GO_REF:0000052, GO:0006672=PMID:14570870, GO:0001553=GO_REF:0000019, GO:0048705=GO_REF:0000019, GO:0030176=PMID:11018465, GO:0044281=Reactome:REACT_111217, GO:0007283=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0010761=GO_REF:0000019, GO:0040014=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:0030097=GO_REF:0000019, GO:0006665=Reactome:REACT_19323, GO:0001822=GO_REF:0000019, GO:0030148=Reactome:REACT_115810, GO:0008209=GO_REF:0000019, GO:0030149=PMID:11018465, GO:0006915=PMID:14570870, GO:0008210=GO_REF:0000019, GO:0060325=GO_REF:0000019, GO:0030170=GO_REF:0000002, GO:0008117=PMID:11018465, GO:0016831=GO_REF:0000002, GO:0005789=Reactome:REACT_19379, GO:0033327=GO_REF:0000019, GO:0048008=GO_REF:0000019, GO:0001570=GO_REF:0000019, GO:0019752=GO_REF:0000002} O95470 Sphingosine-1-phosphate lyase 1 protein 20100326 {GO:0005515=IPI, GO:0005783=IDA, GO:0006672=IDA, GO:0001553=IEA, GO:0048705=IEA, GO:0030176=NAS, GO:0044281=TAS, GO:0007283=IEA, GO:0009791=IEA, GO:0010761=IEA, GO:0040014=IEA, GO:0060021=IEA, GO:0030097=IEA, GO:0006665=TAS, GO:0001822=IEA, GO:0030148=TAS, GO:0008209=IEA, GO:0030149=NAS, GO:0006915=IDA, GO:0008210=IEA, GO:0060325=IEA, GO:0030170=IEA, GO:0008117=NAS, GO:0016831=IEA, GO:0005789=TAS, GO:0033327=IEA, GO:0048008=IEA, GO:0001570=IEA, GO:0019752=IEA} Leydig cell differentiation, androgen metabolic process, apoptotic process, carboxylic acid metabolic process, ceramide metabolic process, estrogen metabolic process, face morphogenesis, fibroblast migration, hemopoiesis, kidney development, luteinization, palate development, platelet-derived growth factor receptor signaling pathway, post-embryonic development, regulation of multicellular organism growth, skeletal system morphogenesis, small molecule metabolic process, spermatogenesis, sphingolipid biosynthetic process, sphingolipid catabolic process, sphingolipid metabolic process, vasculogenesis endoplasmic reticulum, endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane carboxy-lyase activity, protein binding, pyridoxal phosphate binding, sphinganine-1-phosphate aldolase activity Human SGPP1 Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0042392=GO_REF:0000019, GO:0030148=Reactome:REACT_115810, GO:0005789=Reactome:REACT_19392, GO:0006670=GO_REF:0000019, GO:0006915=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0006668=GO_REF:0000019} Q9BX95 Sphingosine-1-phosphate phosphatase 1 protein 20130301 {GO:0006665=TAS, GO:0042392=IEA, GO:0030148=TAS, GO:0005789=TAS, GO:0006670=IEA, GO:0006915=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0006668=IEA} apoptotic process, small molecule metabolic process, sphinganine-1-phosphate metabolic process, sphingolipid biosynthetic process, sphingolipid metabolic process, sphingosine metabolic process endoplasmic reticulum membrane, integral to membrane sphingosine-1-phosphate phosphatase activity Human SGSH Reactome UniProtKB {GO:0005975=Reactome:REACT_474, GO:0006027=Reactome:REACT_120752, GO:0044281=Reactome:REACT_111217, GO:0006029=PMID:7493035, GO:0016250=GO_REF:0000003, GO:0008484=GO_REF:0000002, GO:0003824=PMID:7493035, GO:0030203=Reactome:REACT_121315, GO:0046872=GO_REF:0000037, GO:0043202=Reactome:REACT_121274} P51688 N-sulphoglucosamine sulphohydrolase protein 20130301 {GO:0005975=TAS, GO:0006027=TAS, GO:0044281=TAS, GO:0006029=TAS, GO:0016250=IEA, GO:0008484=IEA, GO:0003824=TAS, GO:0030203=TAS, GO:0046872=IEA, GO:0043202=TAS} carbohydrate metabolic process, glycosaminoglycan catabolic process, glycosaminoglycan metabolic process, proteoglycan metabolic process, small molecule metabolic process lysosomal lumen N-sulfoglucosamine sulfohydrolase activity, catalytic activity, metal ion binding, sulfuric ester hydrolase activity Human SGSM2 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0005097=GO_REF:0000002} O43147 Small G protein signaling modulator 2 protein 20130413 {GO:0005622=IEA, GO:0005097=IEA} intracellular Rab GTPase activator activity Human InterPro:IPR000195 SGSM3 UniProtKB UniProtKB {GO:0005515=PMID:17509819, GO:0005622=GO_REF:0000002, GO:0017137=PMID:17509819, GO:0005737=GO_REF:0000039, GO:0045732=GO_REF:0000019, GO:0032486=PMID:17509819, GO:0032483=PMID:17509819, GO:0005921=GO_REF:0000019, GO:0007050=GO_REF:0000037, GO:0005097=GO_REF:0000002} Q96HU1 Small G protein signaling modulator 3 protein 20070927 {GO:0005515=IPI, GO:0005622=IEA, GO:0017137=IDA, GO:0005737=IEA, GO:0045732=IEA, GO:0032486=IEP, GO:0032483=IEP, GO:0005921=IEA, GO:0007050=IEA, GO:0005097=IEA} Rap protein signal transduction, cell cycle arrest, positive regulation of protein catabolic process, regulation of Rab protein signal transduction cytoplasm, gap junction, intracellular Rab GTPase activator activity, Rab GTPase binding, protein binding Human UniProtKB:P35240 SGTA LIFEdb UniProtKB {GO:0005515=PMID:21988832, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000054, GO:0019048=GO_REF:0000037} O43765 Small glutamine-rich tetratricopeptide repeat-containing protein alpha protein 20100607 {GO:0005515=IPI, GO:0008150=ND, GO:0005737=IDA, GO:0019048=IEA} biological_process, virus-host interaction cytoplasm protein binding Human SGTB null null {} null null null null {} null null null SH2B1 Reactome UniProtKB {GO:0035556=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0007596=Reactome:REACT_604, GO:0030032=GO_REF:0000019, GO:0006928=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0045840=GO_REF:0000019, GO:0004871=GO_REF:0000002, GO:2000278=GO_REF:0000019, GO:0005829=Reactome:REACT_115792} Q9NRF2 SH2B adapter protein 1 protein 20130301 {GO:0035556=IEA, GO:0005543=IEA, GO:0016020=IEA, GO:0007596=TAS, GO:0030032=IEA, GO:0006928=IEA, GO:0005634=IEA, GO:0045840=IEA, GO:0004871=IEA, GO:2000278=IEA, GO:0005829=TAS} blood coagulation, cellular component movement, intracellular signal transduction, lamellipodium assembly, positive regulation of mitosis, regulation of DNA biosynthetic process cytosol, membrane, nucleus phospholipid binding, signal transducer activity Human SH2B2 GOC UniProtKB {GO:0008286=GO_REF:0000024, GO:0001725=GO_REF:0000019, GO:0030036=GO_REF:0000019, GO:0005886=PMID:9989826, GO:0005884=GO_REF:0000019, GO:0019221=GO_REF:0000019, GO:0019222=GO_REF:0000019, GO:0046425=PMID:10374881, GO:0046578=GO_REF:0000019, GO:0001726=GO_REF:0000019, GO:0050851=GO_REF:0000019, GO:0005829=Reactome:REACT_111199, GO:0007399=GO_REF:0000019, GO:0035556=PMID:9233773, GO:0007165=PMID:9233773, GO:0005737=PMID:9989826, GO:0008269=PMID:10374881, GO:0005543=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0050873=GO_REF:0000019, GO:0005070=PMID:9233773, GO:0005068=GO_REF:0000019, GO:0004871=GO_REF:0000002, GO:0001922=GO_REF:0000019} O14492 SH2B adapter protein 2 protein 20130413 {GO:0008286=ISS, GO:0001725=IEA, GO:0030036=IEA, GO:0005886=IDA, GO:0005884=IEA, GO:0019221=IEA, GO:0019222=IEA, GO:0046425=IDA, GO:0046578=IEA, GO:0001726=IEA, GO:0050851=IEA, GO:0005829=TAS, GO:0007399=IEA, GO:0035556=IDA, GO:0007165=TAS, GO:0005737=IDA, GO:0008269=IDA, GO:0005543=IEA, GO:0007596=TAS, GO:0050873=IEA, GO:0005070=IDA, GO:0005068=IEA, GO:0004871=IEA, GO:0001922=IEA} B-1 B cell homeostasis, actin cytoskeleton organization, antigen receptor-mediated signaling pathway, blood coagulation, brown fat cell differentiation, cytokine-mediated signaling pathway, insulin receptor signaling pathway, intracellular signal transduction, nervous system development, regulation of JAK-STAT cascade, regulation of Ras protein signal transduction, regulation of metabolic process, signal transduction actin filament, cytoplasm, cytosol, plasma membrane, ruffle, stress fiber JAK pathway signal transduction adaptor activity, SH3/SH2 adaptor activity, phospholipid binding, signal transducer activity, transmembrane receptor protein tyrosine kinase adaptor activity Human SH2B3 Reactome UniProtKB {GO:0035556=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0042301=GO_REF:0000019, GO:0004871=GO_REF:0000002, GO:0035162=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0030154=GO_REF:0000019, GO:0005829=Reactome:REACT_111099} Q9UQQ2 SH2B adapter protein 3 protein 20130301 {GO:0035556=IEA, GO:0005543=IEA, GO:0007596=TAS, GO:0042301=IEA, GO:0004871=IEA, GO:0035162=IEA, GO:0032403=IEA, GO:0030154=IEA, GO:0005829=TAS} blood coagulation, cell differentiation, embryonic hemopoiesis, intracellular signal transduction cytosol phosphate ion binding, phospholipid binding, protein complex binding, signal transducer activity Human SH2D1A UniProtKB UniProtKB {GO:0005737=PMID:9774102, GO:0006968=PMID:9774102, GO:0005070=PMID:9774102, GO:0006959=GO_REF:0000019, GO:0045954=GO_REF:0000019, GO:0007267=PMID:9774102} O60880 SH2 domain-containing protein 1A protein 20010912 {GO:0005737=IDA, GO:0006968=NAS, GO:0005070=NAS, GO:0006959=IEA, GO:0045954=IEA, GO:0007267=IDA} cell-cell signaling, cellular defense response, humoral immune response, positive regulation of natural killer cell mediated cytotoxicity cytoplasm SH3/SH2 adaptor activity Human SH2D1B UniProtKB UniProtKB {GO:0005622=PMID:16920955, GO:0045089=GO_REF:0000024, GO:0002717=GO_REF:0000024, GO:0030674=PMID:16425036, GO:0002366=GO_REF:0000024} O14796 SH2 domain-containing protein 1B protein 20111129 {GO:0005622=IDA, GO:0045089=ISS, GO:0002717=ISS, GO:0030674=TAS, GO:0002366=ISS} leukocyte activation involved in immune response, positive regulation of innate immune response, positive regulation of natural killer cell mediated immunity intracellular protein binding, bridging Human UniProtKB:O35324 SH2D2A PINC UniProtKB {GO:0007165=PMID:9468509, GO:0005737=GO_REF:0000039, GO:0017124=GO_REF:0000037, GO:0008283=GO_REF:0000019, GO:0005070=PMID:9468509, GO:0001525=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q9NP31 SH2 domain-containing protein 2A protein 20050308 {GO:0007165=TAS, GO:0005737=IEA, GO:0017124=IEA, GO:0008283=IEA, GO:0005070=TAS, GO:0001525=IEA, GO:0030154=IEA} angiogenesis, cell differentiation, cell proliferation, signal transduction cytoplasm SH3 domain binding, SH3/SH2 adaptor activity Human SH2D3A PINC UniProtKB {GO:0005622=GO_REF:0000002, GO:0005085=GO_REF:0000002, GO:0007264=GO_REF:0000002, GO:0005070=PMID:10187783, GO:0007254=PMID:10187783} Q9BRG2 SH2 domain-containing protein 3A protein 20061107 {GO:0005622=IEA, GO:0005085=IEA, GO:0007264=IEA, GO:0005070=TAS, GO:0007254=TAS} JNK cascade, small GTPase mediated signal transduction intracellular SH3/SH2 adaptor activity, guanyl-nucleotide exchange factor activity Human SH2D3C PINC UniProtKB {GO:0005622=GO_REF:0000002, GO:0005085=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0016020=GO_REF:0000039, GO:0007264=GO_REF:0000002, GO:0005070=PMID:10187783, GO:0007254=PMID:10187783} Q8N5H7 SH2 domain-containing protein 3C protein 20061107 {GO:0005622=IEA, GO:0005085=IEA, GO:0005737=IEA, GO:0016020=IEA, GO:0007264=IEA, GO:0005070=TAS, GO:0007254=TAS} JNK cascade, small GTPase mediated signal transduction cytoplasm, intracellular, membrane SH3/SH2 adaptor activity, guanyl-nucleotide exchange factor activity Human SH2D4A HPA UniProtKB {GO:0005515=PMID:19389623, GO:0005737=GO_REF:0000052, GO:0019902=PMID:19389623, GO:0010923=PMID:19389623, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9H788 SH2 domain-containing protein 4A protein 20080205 {GO:0005515=IPI, GO:0005737=IDA, GO:0019902=IDA, GO:0010923=IDA, GO:0005730=IDA, GO:0005634=IDA} negative regulation of phosphatase activity cytoplasm, nucleolus, nucleus phosphatase binding, protein binding Human SH2D5 null null {} null null null null {} null null null SH3BGR PINC UniProtKB {GO:0017124=GO_REF:0000037, GO:0006461=PMID:9050928, GO:0005070=PMID:9050928, GO:0005829=PMID:16780588} P55822 SH3 domain-binding glutamic acid-rich protein protein 20030904 {GO:0017124=IEA, GO:0006461=TAS, GO:0005070=TAS, GO:0005829=IDA} protein complex assembly cytosol SH3 domain binding, SH3/SH2 adaptor activity Human SH3BGRL PINC UniProtKB {GO:0005737=PMID:16130169, GO:0017124=GO_REF:0000037, GO:0005070=PMID:9642120, GO:0005634=PMID:16130169} O75368 SH3 domain-binding glutamic acid-rich-like protein protein 20030904 {GO:0005737=TAS, GO:0017124=IEA, GO:0005070=TAS, GO:0005634=TAS} cytoplasm, nucleus SH3 domain binding, SH3/SH2 adaptor activity Human SH3BGRL2 HPA UniProtKB {GO:0017124=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9UJC5 SH3 domain-binding glutamic acid-rich-like protein 2 protein 20120912 {GO:0017124=IEA, GO:0005730=IDA, GO:0005634=IDA} nucleolus, nucleus SH3 domain binding NOT Human SH3BGRL3 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0015035=GO_REF:0000002, GO:0009055=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0045454=GO_REF:0000002} Q9H299 SH3 domain-binding glutamic acid-rich-like protein 3 protein 20101115 {GO:0005737=IDA, GO:0015035=IEA, GO:0009055=IEA, GO:0005634=IEA, GO:0045454=IEA} cell redox homeostasis cytoplasm, nucleus electron carrier activity, protein disulfide oxidoreductase activity Human SH3BP1 ENSEMBL UniProtKB {GO:0007165=GO_REF:0000002, GO:0017124=GO_REF:0000019, GO:0005737=GO_REF:0000002, GO:0005096=GO_REF:0000037} Q9Y3L3 SH3 domain-binding protein 1 protein 20130413 {GO:0007165=IEA, GO:0017124=IEA, GO:0005737=IEA, GO:0005096=IEA} signal transduction cytoplasm GTPase activator activity, SH3 domain binding Human Ensembl:ENSMUSP00000052181 SH3BP2 IntAct UniProtKB {GO:0005515=PMID:22153077, GO:0007165=PMID:9299232, GO:0017124=GO_REF:0000037, GO:0005543=GO_REF:0000002, GO:0005070=PMID:9299232} P78314 SH3 domain-binding protein 2 protein 20130415 {GO:0005515=IPI, GO:0007165=TAS, GO:0017124=IEA, GO:0005543=IEA, GO:0005070=TAS} signal transduction SH3 domain binding, SH3/SH2 adaptor activity, phospholipid binding, protein binding Human UniProtKB:Q9H2K2 SH3BP4 IntAct UniProtKB {GO:0005515=PMID:18654987, GO:0043090=PMID:22575674, GO:0032007=PMID:22575674, GO:0030308=PMID:22575674, GO:0008285=PMID:22575674, GO:0030136=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0061462=PMID:22575674, GO:0006897=GO_REF:0000037, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005905=GO_REF:0000039, GO:0050790=PMID:22575674, GO:0005737=PMID:22575674, GO:0071230=PMID:22575674, GO:0005092=PMID:22575674, GO:0017016=PMID:22575674, GO:0034260=PMID:22575674, GO:0010508=PMID:22575674} Q9P0V3 SH3 domain-binding protein 4 protein 20130415 {GO:0005515=IPI, GO:0043090=IMP, GO:0032007=IMP, GO:0030308=IMP, GO:0008285=IMP, GO:0030136=IEA, GO:0005634=IEA, GO:0005575=ND, GO:0061462=IMP, GO:0006897=IEA, GO:0008150=ND, GO:0003674=ND, GO:0005905=IEA, GO:0050790=IMP, GO:0005737=IDA, GO:0071230=IMP, GO:0005092=IMP, GO:0017016=IPI, GO:0034260=IDA, GO:0010508=IMP} amino acid import, biological_process, cellular response to amino acid stimulus, endocytosis, negative regulation of GTPase activity, negative regulation of TOR signaling cascade, negative regulation of cell growth, negative regulation of cell proliferation, positive regulation of autophagy, protein localization to lysosome, regulation of catalytic activity cellular_component, clathrin-coated vesicle, coated pit, cytoplasm, nucleus GDP-dissociation inhibitor activity, Ras GTPase binding, molecular_function, protein binding Human UniProtKB:Q9ULV3 SH3BP5 IntAct UniProtKB {GO:0005515=PMID:9571151, GO:0035556=PMID:10339589, GO:0005739=GO_REF:0000039, GO:0007165=PMID:9571151, GO:0005737=PMID:9571151, GO:0017124=GO_REF:0000037, GO:0004860=PMID:10339589, GO:0006469=GO_REF:0000019} O60239 SH3 domain-binding protein 5 protein 20130415 {GO:0005515=IPI, GO:0035556=IDA, GO:0005739=IEA, GO:0007165=TAS, GO:0005737=TAS, GO:0017124=IEA, GO:0004860=IDA, GO:0006469=IEA} intracellular signal transduction, negative regulation of protein kinase activity, signal transduction cytoplasm, mitochondrion SH3 domain binding, protein binding, protein kinase inhibitor activity Human UniProtKB:Q06187 SH3BP5L null null {} null null null null {} null null null SH3D19 HPA UniProtKB {GO:0051044=PMID:15280379, GO:0005794=GO_REF:0000052, GO:0005886=PMID:15280379, GO:0022604=PMID:21834987, GO:0007010=PMID:21834987, GO:0005730=GO_REF:0000052, GO:0006892=Reactome:REACT_11235, GO:0005634=GO_REF:0000052, GO:0016044=Reactome:REACT_11123, GO:0005829=Reactome:REACT_19237} Q5HYK7 SH3 domain-containing protein 19 protein 20090616 {GO:0051044=IMP, GO:0005794=IDA, GO:0005886=IDA, GO:0022604=IMP, GO:0007010=IMP, GO:0005730=IDA, GO:0006892=TAS, GO:0005634=IDA, GO:0016044=TAS, GO:0005829=TAS} cellular membrane organization, cytoskeleton organization, positive regulation of membrane protein ectodomain proteolysis, post-Golgi vesicle-mediated transport, regulation of cell morphogenesis Golgi apparatus, cytosol, nucleolus, nucleus, plasma membrane Human SH3GL1 HPA UniProtKB {GO:0005515=PMID:19060904, GO:0007165=PMID:9169142, GO:0005737=GO_REF:0000052, GO:0051020=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0019902=GO_REF:0000019, GO:0031901=GO_REF:0000039, GO:0002102=GO_REF:0000039, GO:0042995=GO_REF:0000037, GO:0007417=PMID:9169142, GO:0008289=GO_REF:0000037, GO:0006897=GO_REF:0000037} Q99961 Endophilin-A2 protein 20111111 {GO:0005515=IPI, GO:0007165=TAS, GO:0005737=IDA, GO:0051020=IEA, GO:0030054=IEA, GO:0019902=IEA, GO:0031901=IEA, GO:0002102=IEA, GO:0042995=IEA, GO:0007417=TAS, GO:0008289=IEA, GO:0006897=IEA} central nervous system development, endocytosis, signal transduction cell junction, cell projection, cytoplasm, early endosome membrane, podosome GTPase binding, lipid binding, phosphatase binding, protein binding Human SH3GL2 HPA UniProtKB {GO:0005515=PMID:10531379, GO:0048011=Reactome:REACT_11061, GO:0005886=Reactome:REACT_120835, GO:0042059=Reactome:REACT_12484, GO:0006892=Reactome:REACT_11235, GO:0048488=GO_REF:0000019, GO:0007417=PMID:9169142, GO:0042802=PMID:16115810, GO:0008289=GO_REF:0000037, GO:0005829=Reactome:REACT_19334, GO:0019886=Reactome:REACT_121399, GO:0007165=PMID:9169142, GO:0005737=GO_REF:0000052, GO:0000139=Reactome:REACT_19334, GO:0007173=Reactome:REACT_9417, GO:0007411=Reactome:REACT_18266, GO:0002090=GO_REF:0000019, GO:0030669=Reactome:REACT_121177, GO:0016044=Reactome:REACT_11123} Q99962 Endophilin-A1 protein 20111111 {GO:0005515=IPI, GO:0048011=TAS, GO:0005886=TAS, GO:0042059=TAS, GO:0006892=TAS, GO:0048488=IEA, GO:0007417=TAS, GO:0042802=IPI, GO:0008289=IEA, GO:0005829=TAS, GO:0019886=TAS, GO:0007165=TAS, GO:0005737=IDA, GO:0000139=TAS, GO:0007173=TAS, GO:0007411=TAS, GO:0002090=IEA, GO:0030669=TAS, GO:0016044=TAS} antigen processing and presentation of exogenous peptide antigen via MHC class II, axon guidance, cellular membrane organization, central nervous system development, epidermal growth factor receptor signaling pathway, negative regulation of epidermal growth factor receptor signaling pathway, neurotrophin TRK receptor signaling pathway, post-Golgi vesicle-mediated transport, regulation of receptor internalization, signal transduction, synaptic vesicle endocytosis Golgi membrane, clathrin-coated endocytic vesicle membrane, cytoplasm, cytosol, plasma membrane identical protein binding, lipid binding, protein binding Human SH3GL3 IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0007165=PMID:9169142, GO:0005737=GO_REF:0000002, GO:0031901=GO_REF:0000039, GO:0007417=PMID:9169142, GO:0042802=PMID:16115810, GO:0008289=GO_REF:0000037, GO:0006897=GO_REF:0000037} Q99963 Endophilin-A3 protein 20130415 {GO:0005515=IPI, GO:0007165=TAS, GO:0005737=IEA, GO:0031901=IEA, GO:0007417=TAS, GO:0042802=IPI, GO:0008289=IEA, GO:0006897=IEA} central nervous system development, endocytosis, signal transduction cytoplasm, early endosome membrane identical protein binding, lipid binding, protein binding Human UniProtKB:Q99963 SH3GLB1 HPA UniProtKB {GO:0005515=PMID:21988832, GO:0005504=GO_REF:0000019, GO:0043066=PMID:11161816, GO:0042171=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0005741=GO_REF:0000039, GO:0042803=PMID:11161816, GO:0042802=PMID:20562859, GO:0043234=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:1900740=GO_REF:0000019, GO:0000139=GO_REF:0000039, GO:0051084=GO_REF:0000019, GO:0006654=GO_REF:0000019} Q9Y371 Endophilin-B1 protein 20101115 {GO:0005515=IPI, GO:0005504=IEA, GO:0043066=IDA, GO:0042171=IEA, GO:0006915=IEA, GO:0005741=IEA, GO:0042803=IPI, GO:0042802=IPI, GO:0043234=IEA, GO:0005737=IDA, GO:1900740=IEA, GO:0000139=IEA, GO:0051084=IEA, GO:0006654=IEA} 'de novo' posttranslational protein folding, apoptotic process, negative regulation of apoptotic process, phosphatidic acid biosynthetic process, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway Golgi membrane, cytoplasm, mitochondrial outer membrane, protein complex fatty acid binding, identical protein binding, lysophosphatidic acid acyltransferase activity, protein binding, protein homodimerization activity Human SH3GLB2 HPA UniProtKB {GO:0005515=PMID:20562859, GO:0005737=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9NR46 Endophilin-B2 protein 20090616 {GO:0005515=IPI, GO:0005737=IDA, GO:0005634=IDA} cytoplasm, nucleus protein binding Human SH3KBP1 IntAct UniProtKB {GO:0005515=PMID:16751601, GO:0043005=GO_REF:0000039, GO:0017124=GO_REF:0000037, GO:0005886=Reactome:REACT_118834, GO:0008360=PMID:21834987, GO:0042059=Reactome:REACT_12484, GO:0007267=PMID:10679202, GO:0006915=GO_REF:0000037, GO:0045202=GO_REF:0000037, GO:0005829=Reactome:REACT_118834, GO:0006897=GO_REF:0000037, GO:0007173=Reactome:REACT_9417, GO:0016477=PMID:21834987, GO:0016301=GO_REF:0000038, GO:0007010=PMID:21834987, GO:0005856=GO_REF:0000039, GO:0005925=GO_REF:0000039, GO:0030659=GO_REF:0000039} Q96B97 SH3 domain-containing kinase-binding protein 1 protein 20130415 {GO:0005515=IPI, GO:0043005=IEA, GO:0017124=IEA, GO:0005886=TAS, GO:0008360=IMP, GO:0042059=TAS, GO:0007267=NAS, GO:0006915=IEA, GO:0045202=IEA, GO:0005829=TAS, GO:0006897=IEA, GO:0007173=TAS, GO:0016477=IMP, GO:0016301=IEA, GO:0007010=IMP, GO:0005856=IEA, GO:0005925=IEA, GO:0030659=IEA} apoptotic process, cell migration, cell-cell signaling, cytoskeleton organization, endocytosis, epidermal growth factor receptor signaling pathway, negative regulation of epidermal growth factor receptor signaling pathway, regulation of cell shape cytoplasmic vesicle membrane, cytoskeleton, cytosol, focal adhesion, neuron projection, plasma membrane, synapse SH3 domain binding, kinase activity, protein binding Human UniProtKB:O94850 SH3PXD2A UniProtKB UniProtKB {GO:0005515=PMID:20609497, GO:0005737=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0007154=GO_REF:0000002, GO:0006801=PMID:19755710, GO:0002102=PMID:18417249, GO:0042995=GO_REF:0000037, GO:0035091=GO_REF:0000002} Q5TCZ1 SH3 and PX domain-containing protein 2A protein 20110629 {GO:0005515=IPI, GO:0005737=IEA, GO:0030054=IEA, GO:0007154=IEA, GO:0006801=IDA, GO:0002102=IDA, GO:0042995=IEA, GO:0035091=IEA} cell communication, superoxide metabolic process cell junction, cell projection, cytoplasm, podosome phosphatidylinositol binding, protein binding Human UniProtKB:Q86UR1 SH3PXD2B InterPro UniProtKB {GO:0005515=PMID:19755710, GO:0071800=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0001654=PMID:20137777, GO:0006801=PMID:19755710, GO:0070273=GO_REF:0000019, GO:0080025=GO_REF:0000024, GO:0002102=GO_REF:0000024, GO:0072657=PMID:19755710, GO:0042995=GO_REF:0000037, GO:0032266=GO_REF:0000024, GO:0030154=GO_REF:0000037, GO:0007507=PMID:20137777, GO:0060348=PMID:20137777, GO:0005737=GO_REF:0000024, GO:0001501=PMID:20137777, GO:0007154=GO_REF:0000002, GO:0022617=PMID:19755710, GO:0045600=GO_REF:0000019, GO:0035091=GO_REF:0000002, GO:0042169=GO_REF:0000024, GO:0060612=GO_REF:0000024, GO:0010314=GO_REF:0000024} G3V144 SH3 and PX domain-containing protein 2B protein 20130413 {GO:0005515=IPI, GO:0071800=ISS, GO:0030054=IEA, GO:0001654=IMP, GO:0006801=IDA, GO:0070273=IEA, GO:0080025=ISS, GO:0002102=ISS, GO:0072657=IDA, GO:0042995=IEA, GO:0032266=ISS, GO:0030154=IEA, GO:0007507=IMP, GO:0060348=IMP, GO:0005737=ISS, GO:0001501=IMP, GO:0007154=IEA, GO:0022617=IMP, GO:0045600=IEA, GO:0035091=IEA, GO:0042169=ISS, GO:0060612=ISS, GO:0010314=ISS} adipose tissue development, bone development, cell communication, cell differentiation, extracellular matrix disassembly, eye development, heart development, podosome assembly, positive regulation of fat cell differentiation, protein localization to membrane, skeletal system development, superoxide metabolic process cell junction, cell projection, cytoplasm, podosome SH2 domain binding, phosphatidylinositol binding, phosphatidylinositol-3,5-bisphosphate binding, phosphatidylinositol-3-phosphate binding, phosphatidylinositol-4-phosphate binding, phosphatidylinositol-5-phosphate binding, protein binding Human InterPro:IPR001683 SH3RF1 IntAct UniProtKB {GO:0005515=PMID:21586138, GO:2001237=PMID:21586138, GO:0048471=GO_REF:0000039, GO:0043066=PMID:21586138, GO:0005794=GO_REF:0000039, GO:0016567=GO_REF:0000041, GO:0016874=GO_REF:0000037, GO:0006917=GO_REF:0000019, GO:0030027=GO_REF:0000039, GO:0005829=PMID:21586138, GO:0046328=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0043154=PMID:21586138, GO:0005078=GO_REF:0000019} Q7Z6J0 E3 ubiquitin-protein ligase SH3RF1 protein 20130415 {GO:0005515=IPI, GO:2001237=IMP, GO:0048471=IEA, GO:0043066=IMP, GO:0005794=IEA, GO:0016567=IEA, GO:0016874=IEA, GO:0006917=IEA, GO:0030027=IEA, GO:0005829=IDA, GO:0046328=IEA, GO:0008270=IEA, GO:0043154=IMP, GO:0005078=IEA} induction of apoptosis, negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of extrinsic apoptotic signaling pathway, protein ubiquitination, regulation of JNK cascade Golgi apparatus, cytosol, lamellipodium, perinuclear region of cytoplasm MAP-kinase scaffold activity, ligase activity, protein binding, zinc ion binding Human UniProtKB:O43255 SH3RF2 IntAct UniProtKB {GO:0005515=PMID:22321011, GO:0016567=GO_REF:0000041, GO:0019902=PMID:19389623, GO:0010923=PMID:19389623, GO:0016874=GO_REF:0000037, GO:0004864=GO_REF:0000037, GO:0008157=PMID:19945436, GO:0008270=GO_REF:0000002} Q8TEC5 Putative E3 ubiquitin-protein ligase SH3RF2 protein 20130415 {GO:0005515=IPI, GO:0016567=IEA, GO:0019902=IDA, GO:0010923=IDA, GO:0016874=IEA, GO:0004864=IEA, GO:0008157=IDA, GO:0008270=IEA} negative regulation of phosphatase activity, protein ubiquitination ligase activity, phosphatase binding, protein binding, protein phosphatase 1 binding, protein phosphatase inhibitor activity, zinc ion binding Human UniProtKB:P62136 SH3RF3 InterPro UniProtKB {GO:0008270=GO_REF:0000002} Q8TEJ3 SH3 domain-containing RING finger protein 3 protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR001841 SH3TC2 ENSEMBL UniProtKB {GO:0005886=GO_REF:0000019, GO:0055037=GO_REF:0000019, GO:0032287=GO_REF:0000019} Q8TF17 SH3 domain and tetratricopeptide repeat-containing protein 2 protein 20130413 {GO:0005886=IEA, GO:0055037=IEA, GO:0032287=IEA} peripheral nervous system myelin maintenance plasma membrane, recycling endosome Human Ensembl:ENSMUSP00000055094 SH3YL1 MGI UniProtKB {GO:0006661=GO_REF:0000019, GO:0019902=PMID:21624956, GO:1900027=GO_REF:0000019, GO:0032587=PMID:21624956, GO:0035091=PMID:21624956} Q96HL8 SH3 domain-containing YSC84-like protein 1 protein 20120820 {GO:0006661=IEA, GO:0019902=IDA, GO:1900027=IEA, GO:0032587=IDA, GO:0035091=IDA} phosphatidylinositol biosynthetic process, regulation of ruffle assembly ruffle membrane phosphatase binding, phosphatidylinositol binding Human SHANK1 BHF-UCL UniProtKB {GO:0005515=PMID:11583995, GO:0043005=GO_REF:0000024, GO:0017124=GO_REF:0000024, GO:0008328=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000024, GO:0017146=GO_REF:0000019, GO:2000311=GO_REF:0000024, GO:0035418=GO_REF:0000024, GO:0031877=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0030425=PMID:10551867, GO:0042802=GO_REF:0000024, GO:0005622=PMID:10551867, GO:0005737=GO_REF:0000039, GO:0030160=GO_REF:0000024, GO:0043197=GO_REF:0000024, GO:0042048=GO_REF:0000019, GO:0045211=GO_REF:0000024, GO:0097110=GO_REF:0000024, GO:0032232=GO_REF:0000019, GO:0050885=GO_REF:0000024, GO:0060997=GO_REF:0000024, GO:0060999=GO_REF:0000019, GO:0007016=PMID:10551867, GO:0071532=GO_REF:0000024, GO:0008306=GO_REF:0000024, GO:2000463=GO_REF:0000024, GO:0007616=GO_REF:0000024, GO:0014069=GO_REF:0000024, GO:0008022=GO_REF:0000019, GO:0071625=PMID:22503632, GO:0060076=GO_REF:0000024, GO:0060074=GO_REF:0000019, GO:0050894=PMID:22503632, GO:0006461=GO_REF:0000024, GO:0035255=GO_REF:0000024, GO:0016020=PMID:10551867, GO:0035176=PMID:22503632, GO:0060013=GO_REF:0000019, GO:0046959=GO_REF:0000019} Q9Y566 SH3 and multiple ankyrin repeat domains protein 1 protein 20120503 {GO:0005515=IPI, GO:0043005=ISS, GO:0017124=ISS, GO:0008328=ISS, GO:0030054=IEA, GO:0005886=ISS, GO:0017146=IEA, GO:2000311=ISS, GO:0035418=ISS, GO:0031877=IEA, GO:0032403=IEA, GO:0030425=NAS, GO:0042802=ISS, GO:0005622=NAS, GO:0005737=IEA, GO:0030160=ISS, GO:0043197=ISS, GO:0042048=IEA, GO:0045211=ISS, GO:0097110=ISS, GO:0032232=IEA, GO:0050885=ISS, GO:0060997=ISS, GO:0060999=IEA, GO:0007016=NAS, GO:0071532=ISS, GO:0008306=ISS, GO:2000463=ISS, GO:0007616=ISS, GO:0014069=ISS, GO:0008022=IEA, GO:0071625=IMP, GO:0060076=ISS, GO:0060074=IEA, GO:0050894=IMP, GO:0006461=ISS, GO:0035255=ISS, GO:0016020=IDA, GO:0035176=IMP, GO:0060013=IEA, GO:0046959=IEA} associative learning, cytoskeletal anchoring at plasma membrane, dendritic spine morphogenesis, determination of affect, habituation, long-term memory, negative regulation of actin filament bundle assembly, neuromuscular process controlling balance, olfactory behavior, positive regulation of dendritic spine development, positive regulation of excitatory postsynaptic membrane potential, protein complex assembly, protein localization to synapse, regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity, righting reflex, social behavior, synapse maturation, vocalization behavior N-methyl-D-aspartate selective glutamate receptor complex, cell junction, cytoplasm, dendrite, dendritic spine, excitatory synapse, intracellular, ionotropic glutamate receptor complex, membrane, neuron projection, plasma membrane, postsynaptic density, postsynaptic membrane GKAP/Homer scaffold activity, SH3 domain binding, ankyrin repeat binding, identical protein binding, ionotropic glutamate receptor binding, protein C-terminus binding, protein binding, protein complex binding, scaffold protein binding, somatostatin receptor binding Human SHANK2 BHF-UCL UniProtKB {GO:0005515=PMID:17474147, GO:0060170=GO_REF:0000024, GO:0017124=GO_REF:0000037, GO:0008328=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000024, GO:0005883=GO_REF:0000019, GO:0014069=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0035556=GO_REF:0000029, GO:0001917=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0030160=PMID:10506216, GO:0035255=GO_REF:0000024, GO:0043197=GO_REF:0000024, GO:0045211=GO_REF:0000024, GO:0001750=GO_REF:0000019} Q9UPX8 SH3 and multiple ankyrin repeat domains protein 2 protein 20110218 {GO:0005515=IPI, GO:0060170=ISS, GO:0017124=IEA, GO:0008328=ISS, GO:0030054=IEA, GO:0005886=ISS, GO:0005883=IEA, GO:0014069=IEA, GO:0005575=ND, GO:0035556=NAS, GO:0001917=IEA, GO:0005737=IEA, GO:0030160=NAS, GO:0035255=ISS, GO:0043197=ISS, GO:0045211=ISS, GO:0001750=IEA} intracellular signal transduction cell junction, cellular_component, cilium membrane, cytoplasm, dendritic spine, ionotropic glutamate receptor complex, neurofilament, photoreceptor inner segment, photoreceptor outer segment, plasma membrane, postsynaptic density, postsynaptic membrane GKAP/Homer scaffold activity, SH3 domain binding, ionotropic glutamate receptor binding, protein binding Human UniProtKB:Q80Z38 SHANK3 BHF-UCL UniProtKB {GO:0005515=PMID:21988832, GO:0043005=GO_REF:0000024, GO:0017124=GO_REF:0000037, GO:0060170=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000024, GO:0001838=GO_REF:0000019, GO:0043621=GO_REF:0000019, GO:0051259=GO_REF:0000019, GO:0042802=GO_REF:0000019, GO:1900451=GO_REF:0000019, GO:0097117=GO_REF:0000024, GO:1900452=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0030160=GO_REF:0000024, GO:0097114=GO_REF:0000024, GO:0097113=GO_REF:0000024, GO:0000165=GO_REF:0000019, GO:0045211=GO_REF:0000037, GO:0097110=GO_REF:0000024, GO:0032232=GO_REF:0000019, GO:0021773=GO_REF:0000024, GO:0050885=GO_REF:0000024, GO:0007613=GO_REF:0000024, GO:0007612=GO_REF:0000024, GO:0060997=GO_REF:0000024, GO:0061001=GO_REF:0000019, GO:0060999=GO_REF:0000019, GO:2000969=GO_REF:0000024, GO:0035641=PMID:21423165, GO:2000821=GO_REF:0000019, GO:2000463=GO_REF:0000024, GO:0051968=GO_REF:0000024, GO:0014069=GO_REF:0000024, GO:1900271=GO_REF:0000024, GO:0044309=GO_REF:0000024, GO:0008022=GO_REF:0000024, GO:0071625=PMID:21167025, GO:2000822=PMID:21423165, GO:0048854=GO_REF:0000024, GO:0045794=GO_REF:0000024, GO:0035255=GO_REF:0000024, GO:0035176=GO_REF:0000024, GO:0051835=GO_REF:0000024, GO:0008270=GO_REF:0000019, GO:0097107=GO_REF:0000024, GO:0048170=GO_REF:0000024} Q9BYB0 SH3 and multiple ankyrin repeat domains protein 3 protein 20120404 {GO:0005515=IPI, GO:0043005=ISS, GO:0017124=IEA, GO:0060170=ISS, GO:0030054=IEA, GO:0005886=ISS, GO:0001838=IEA, GO:0043621=IEA, GO:0051259=IEA, GO:0042802=IEA, GO:1900451=IEA, GO:0097117=ISS, GO:1900452=IEA, GO:0005737=IEA, GO:0030160=ISS, GO:0097114=ISS, GO:0097113=ISS, GO:0000165=IEA, GO:0045211=IEA, GO:0097110=ISS, GO:0032232=IEA, GO:0021773=ISS, GO:0050885=ISS, GO:0007613=ISS, GO:0007612=ISS, GO:0060997=ISS, GO:0061001=IEA, GO:0060999=IEA, GO:2000969=ISS, GO:0035641=ISS, GO:2000821=IEA, GO:2000463=ISS, GO:0051968=ISS, GO:0014069=ISS, GO:1900271=ISS, GO:0044309=ISS, GO:0008022=ISS, GO:0071625=ISS, GO:2000822=ISS, GO:0048854=ISS, GO:0045794=ISS, GO:0035255=ISS, GO:0035176=ISS, GO:0051835=ISS, GO:0008270=IEA, GO:0097107=ISS, GO:0048170=ISS} MAPK cascade, N-methyl-D-aspartate receptor clustering, alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering, brain morphogenesis, dendritic spine morphogenesis, embryonic epithelial tube formation, guanylate kinase-associated protein clustering, learning, locomotory exploration behavior, memory, negative regulation of actin filament bundle assembly, negative regulation of cell volume, neuromuscular process controlling balance, positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity, positive regulation of dendritic spine development, positive regulation of excitatory postsynaptic membrane potential, positive regulation of glutamate receptor signaling pathway, positive regulation of long-term neuronal synaptic plasticity, positive regulation of synapse structural plasticity, positive regulation of synaptic transmission, glutamatergic, postsynaptic density assembly, protein oligomerization, regulation of behavioral fear response, regulation of dendritic spine morphogenesis, regulation of grooming behavior, regulation of long term synaptic depression, regulation of long-term synaptic potentiation, social behavior, striatal medium spiny neuron differentiation, vocalization behavior cell junction, cilium membrane, cytoplasm, neuron projection, neuron spine, plasma membrane, postsynaptic density, postsynaptic membrane GKAP/Homer scaffold activity, SH3 domain binding, identical protein binding, ionotropic glutamate receptor binding, protein C-terminus binding, protein binding, protein self-association, scaffold protein binding, zinc ion binding Human UniProtKB:Q4ACU6 SHB PINC UniProtKB {GO:0007165=PMID:8302579, GO:0005737=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0005070=PMID:8302579, GO:0006915=GO_REF:0000037, GO:0001525=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q15464 SH2 domain-containing adapter protein B protein 20030904 {GO:0007165=TAS, GO:0005737=IEA, GO:0005886=IEA, GO:0005070=TAS, GO:0006915=IEA, GO:0001525=IEA, GO:0030154=IEA} angiogenesis, apoptotic process, cell differentiation, signal transduction cytoplasm, plasma membrane SH3/SH2 adaptor activity Human SHBG PINC UniProtKB {GO:0007285=GO_REF:0000019, GO:0005576=PMID:14718574, GO:0005497=PMID:2587256, GO:0009914=GO_REF:0000029, GO:0042803=GO_REF:0000029} P04278 Sex hormone-binding globulin protein 20030904 {GO:0007285=IEA, GO:0005576=NAS, GO:0005497=TAS, GO:0009914=NAS, GO:0042803=NAS} hormone transport, primary spermatocyte growth extracellular region androgen binding, protein homodimerization activity Human SHC1 InterPro UniProtKB {GO:0005515=PMID:21725358, GO:0008286=GO_REF:0000024, GO:0005154=GO_REF:0000024, GO:0008284=PMID:14676841, GO:0005886=Reactome:REACT_150430, GO:0005159=PMID:7541045, GO:0005158=PMID:7537849, GO:0007265=Reactome:REACT_12033, GO:0050900=Reactome:REACT_12051, GO:0030968=Reactome:REACT_18356, GO:0005829=Reactome:REACT_106, GO:0035556=GO_REF:0000002, GO:0007507=GO_REF:0000019, GO:0000187=GO_REF:0000019, GO:0016337=GO_REF:0000019, GO:0005543=PMID:14676841, GO:0007173=Reactome:REACT_9417, GO:0000165=PMID:14676841, GO:0005759=GO_REF:0000039, GO:0007176=PMID:1623525, GO:0005068=PMID:14676841, GO:0030971=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0031532=GO_REF:0000019, GO:0005168=PMID:15488758, GO:0070435=GO_REF:0000024, GO:0045740=GO_REF:0000024, GO:0030168=Reactome:REACT_798, GO:0001525=GO_REF:0000019, GO:0046875=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0004713=Reactome:REACT_115850, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0040008=GO_REF:0000037} Q5T188 SHC-transforming protein 1 protein 20130413 {GO:0005515=IPI, GO:0008286=ISS, GO:0005154=ISS, GO:0008284=NAS, GO:0005886=TAS, GO:0005159=IPI, GO:0005158=IPI, GO:0007265=TAS, GO:0050900=TAS, GO:0030968=TAS, GO:0005829=TAS, GO:0035556=IEA, GO:0007507=IEA, GO:0000187=IEA, GO:0016337=IEA, GO:0005543=TAS, GO:0007173=TAS, GO:0000165=IDA, GO:0005759=IEA, GO:0007176=TAS, GO:0005068=TAS, GO:0030971=IEA, GO:0048011=TAS, GO:0031532=IEA, GO:0005168=IPI, GO:0070435=ISS, GO:0045740=ISS, GO:0030168=TAS, GO:0001525=IEA, GO:0046875=IEA, GO:0007596=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0004713=TAS, GO:0006987=TAS, GO:0044267=TAS, GO:0040008=IEA} MAPK cascade, Ras protein signal transduction, actin cytoskeleton reorganization, activation of MAPK activity, activation of signaling protein activity involved in unfolded protein response, angiogenesis, blood coagulation, cell-cell adhesion, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, heart development, innate immune response, insulin receptor signaling pathway, intracellular signal transduction, leukocyte migration, neurotrophin TRK receptor signaling pathway, platelet activation, positive regulation of DNA replication, positive regulation of cell proliferation, regulation of epidermal growth factor-activated receptor activity, regulation of growth Shc-EGFR complex, cytosol, mitochondrial matrix, plasma membrane ephrin receptor binding, epidermal growth factor receptor binding, insulin receptor binding, insulin-like growth factor receptor binding, neurotrophin TRKA receptor binding, phospholipid binding, protein binding, protein tyrosine kinase activity, receptor tyrosine kinase binding, transmembrane receptor protein tyrosine kinase adaptor activity Human InterPro:IPR006019 SHC2 Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0035556=GO_REF:0000002, GO:0048011=Reactome:REACT_11061, GO:0007265=Reactome:REACT_12033, GO:0005575=GO_REF:0000015, GO:0005829=Reactome:REACT_2010} P98077 SHC-transforming protein 2 protein 20130301 {GO:0008286=TAS, GO:0035556=IEA, GO:0048011=TAS, GO:0007265=TAS, GO:0005575=ND, GO:0005829=TAS} Ras protein signal transduction, insulin receptor signaling pathway, intracellular signal transduction, neurotrophin TRK receptor signaling pathway cellular_component, cytosol Human SHC3 IntAct UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005515=PMID:11877420, GO:0048011=Reactome:REACT_11061, GO:0035249=GO_REF:0000019, GO:0007265=Reactome:REACT_12033, GO:0005575=GO_REF:0000015, GO:0007417=PMID:8808684, GO:0005829=Reactome:REACT_2010, GO:0035556=GO_REF:0000029, GO:0007173=PMID:8808684, GO:0007611=GO_REF:0000019, GO:0004871=PMID:8808684, GO:0007169=PMID:8808684} Q92529 SHC-transforming protein 3 protein 20130415 {GO:0008286=TAS, GO:0005515=IPI, GO:0048011=TAS, GO:0035249=IEA, GO:0007265=TAS, GO:0005575=ND, GO:0007417=TAS, GO:0005829=TAS, GO:0035556=NAS, GO:0007173=TAS, GO:0007611=IEA, GO:0004871=TAS, GO:0007169=TAS} Ras protein signal transduction, central nervous system development, epidermal growth factor receptor signaling pathway, insulin receptor signaling pathway, intracellular signal transduction, learning or memory, neurotrophin TRK receptor signaling pathway, synaptic transmission, glutamatergic, transmembrane receptor protein tyrosine kinase signaling pathway cellular_component, cytosol protein binding, signal transducer activity Human UniProtKB:P05067 SHC4 UniProtKB UniProtKB {GO:0035556=GO_REF:0000002, GO:0030971=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000037, GO:0045211=GO_REF:0000039, GO:0019904=GO_REF:0000019} Q6S5L8 SHC-transforming protein 4 protein 20130413 {GO:0035556=IEA, GO:0030971=IEA, GO:0030054=IEA, GO:0005886=IEA, GO:0045211=IEA, GO:0019904=IEA} intracellular signal transduction cell junction, plasma membrane, postsynaptic membrane protein domain specific binding, receptor tyrosine kinase binding Human UniProtKB-SubCell:SL-0219 SHCBP1 UniProtKB UniProtKB {GO:2000177=GO_REF:0000024, GO:0008543=GO_REF:0000024, GO:0042169=GO_REF:0000019} Q8NEM2 SHC SH2 domain-binding protein 1 protein 20121102 {GO:2000177=ISS, GO:0008543=ISS, GO:0042169=IEA} fibroblast growth factor receptor signaling pathway, regulation of neural precursor cell proliferation SH2 domain binding Human UniProtKB:Q9Z179 SHD null null {} null null null null {} null null null SHE null null {} null null null null {} null null null SHF UniProtKB UniProtKB {GO:0006915=GO_REF:0000037} Q7M4L6 SH2 domain-containing adapter protein F protein 20130413 {GO:0006915=IEA} apoptotic process Human UniProtKB-KW:KW-0053 SHFM1 IntAct UniProtKB {GO:0005515=PMID:10373512, GO:0000502=PMID:15117943, GO:0000724=GO_REF:0000019, GO:0032039=PMID:16239144, GO:0006508=PMID:10373512, GO:0008233=PMID:10373512} P60896 26S proteasome complex subunit DSS1 protein 20130415 {GO:0005515=IPI, GO:0000502=IDA, GO:0000724=IEA, GO:0032039=IDA, GO:0006508=IDA, GO:0008233=IDA} double-strand break repair via homologous recombination, proteolysis integrator complex, proteasome complex peptidase activity, protein binding Human UniProtKB:P51587 SHH BHF-UCL UniProtKB {GO:0005515=PMID:19561609, GO:0034504=GO_REF:0000019, GO:0048706=GO_REF:0000019, GO:0009790=GO_REF:0000024, GO:0030878=GO_REF:0000019, GO:0005615=PMID:19561609, GO:0005113=PMID:8906787, GO:0042130=GO_REF:0000019, GO:0031069=GO_REF:0000019, GO:0048645=GO_REF:0000019, GO:0007507=GO_REF:0000024, GO:0030162=GO_REF:0000024, GO:0060916=GO_REF:0000019, GO:0003140=GO_REF:0000024, GO:0042127=GO_REF:0000024, GO:0060439=GO_REF:0000019, GO:0051155=GO_REF:0000019, GO:0045445=GO_REF:0000019, GO:0016539=GO_REF:0000002, GO:0002320=PMID:14764698, GO:0048839=GO_REF:0000019, GO:0014902=GO_REF:0000019, GO:0001708=GO_REF:0000024, GO:0009986=GO_REF:0000024, GO:0005509=PMID:19561609, GO:0007275=GO_REF:0000038, GO:0021978=GO_REF:0000019, GO:0048643=GO_REF:0000019, GO:0002076=GO_REF:0000019, GO:0080125=GO_REF:0000019, GO:0042307=GO_REF:0000019, GO:0008270=PMID:19561609, GO:0043588=GO_REF:0000019, GO:0060447=GO_REF:0000019, GO:0060445=GO_REF:0000019, GO:0021513=GO_REF:0000019, GO:0042481=GO_REF:0000024, GO:0030177=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0048864=GO_REF:0000024, GO:0045880=GO_REF:0000024, GO:0060664=GO_REF:0000019, GO:0042475=GO_REF:0000019, GO:0021904=GO_REF:0000019, GO:0043010=GO_REF:0000019, GO:0014858=GO_REF:0000019, GO:0004871=PMID:19561609, GO:0048468=GO_REF:0000024, GO:0060458=GO_REF:0000019, GO:0060662=GO_REF:0000019, GO:0060523=GO_REF:0000019, GO:0060738=PMID:12221011, GO:0060459=GO_REF:0000019, GO:0034244=GO_REF:0000019, GO:0060070=GO_REF:0000019, GO:0001569=GO_REF:0000024, GO:0048859=GO_REF:0000019, GO:0005576=GO_REF:0000038, GO:0042981=GO_REF:0000019, GO:0048663=GO_REF:0000024, GO:0060840=GO_REF:0000019, GO:0007398=GO_REF:0000019, GO:0045059=GO_REF:0000024, GO:0048557=GO_REF:0000019, GO:0007596=GO_REF:0000019, GO:0014003=GO_REF:0000019, GO:0060463=GO_REF:0000019, GO:0035116=GO_REF:0000019, GO:0007442=GO_REF:0000019, GO:0045060=GO_REF:0000024, GO:0030901=GO_REF:0000024, GO:0048754=GO_REF:0000024, GO:0030900=GO_REF:0000024, GO:0035115=GO_REF:0000019, GO:0030902=GO_REF:0000024, GO:0060516=GO_REF:0000019, GO:0001570=GO_REF:0000024, GO:0046638=GO_REF:0000024, GO:0001656=GO_REF:0000024, GO:0033089=GO_REF:0000024, GO:0007389=GO_REF:0000024, GO:0001658=GO_REF:0000024, GO:0045109=GO_REF:0000019, GO:0001755=GO_REF:0000024, GO:0048538=GO_REF:0000024, GO:0030010=GO_REF:0000019, GO:0007228=GO_REF:0000024, GO:0007224=GO_REF:0000024, GO:0046639=GO_REF:0000019, GO:0007405=GO_REF:0000024, GO:0009880=PMID:11001584, GO:0001947=GO_REF:0000024, GO:0016015=PMID:8647801, GO:0030539=GO_REF:0000024, GO:0001948=GO_REF:0000019, GO:0007411=GO_REF:0000024, GO:0061189=PMID:10654605, GO:0006508=GO_REF:0000037, GO:0051781=PMID:11331587, GO:0072136=GO_REF:0000024, GO:0071285=GO_REF:0000019, GO:0060685=GO_REF:0000019, GO:0033077=GO_REF:0000024, GO:0030336=GO_REF:0000024, GO:0021938=GO_REF:0000019, GO:0007417=GO_REF:0000024, GO:0060769=GO_REF:0000019, GO:2000729=GO_REF:0000024, GO:0007418=PMID:11001584, GO:0006897=GO_REF:0000019, GO:0061053=GO_REF:0000024, GO:0043237=GO_REF:0000024, GO:0060174=GO_REF:0000019, GO:0045121=GO_REF:0000024, GO:0072001=PMID:17850284, GO:0008233=GO_REF:0000037, GO:0045596=GO_REF:0000024, GO:0060484=GO_REF:0000019, GO:0045893=PMID:10654605, GO:0042733=GO_REF:0000024, GO:0008284=PMID:11331587, GO:0060428=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0030324=GO_REF:0000024, GO:0007267=GO_REF:0000024, GO:0030326=GO_REF:0000024, GO:0009953=GO_REF:0000024, GO:0032435=GO_REF:0000019, GO:0005539=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0060020=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:0030850=GO_REF:0000024, GO:0090090=GO_REF:0000019, GO:0060783=GO_REF:0000019, GO:0060782=GO_REF:0000019, GO:0008209=GO_REF:0000024, GO:0002052=GO_REF:0000019, GO:0006915=GO_REF:0000019, GO:0033092=GO_REF:0000024, GO:0043369=PMID:17227833, GO:0031012=GO_REF:0000019, GO:2000062=GO_REF:0000024, GO:0031016=GO_REF:0000019, GO:2000063=GO_REF:0000024, GO:0048714=GO_REF:0000019, GO:0090370=GO_REF:0000024, GO:0048617=GO_REF:0000019, GO:2000357=GO_REF:0000024, GO:2000358=GO_REF:0000024} Q15465 Sonic hedgehog protein protein 20130128 {GO:0005515=IPI, GO:0034504=IEA, GO:0048706=IEA, GO:0009790=ISS, GO:0030878=IEA, GO:0005615=IDA, GO:0005113=IDA, GO:0042130=IEA, GO:0031069=IEA, GO:0048645=IEA, GO:0007507=ISS, GO:0030162=ISS, GO:0060916=IEA, GO:0003140=ISS, GO:0042127=ISS, GO:0060439=IEA, GO:0051155=IEA, GO:0045445=IEA, GO:0016539=IEA, GO:0002320=IMP, GO:0048839=IEA, GO:0014902=IEA, GO:0001708=ISS, GO:0009986=ISS, GO:0005509=IDA, GO:0007275=IEA, GO:0021978=IEA, GO:0048643=IEA, GO:0002076=IEA, GO:0080125=IEA, GO:0042307=IEA, GO:0008270=IDA, GO:0043588=IEA, GO:0060447=IEA, GO:0060445=IEA, GO:0021513=IEA, GO:0042481=ISS, GO:0030177=IEA, GO:0005634=IEA, GO:0048864=ISS, GO:0045880=ISS, GO:0060664=IEA, GO:0042475=IEA, GO:0021904=IEA, GO:0043010=IEA, GO:0014858=IEA, GO:0004871=IDA, GO:0048468=ISS, GO:0060458=IEA, GO:0060662=IEA, GO:0060523=IEA, GO:0060738=IDA, GO:0060459=IEA, GO:0034244=IEA, GO:0060070=IEA, GO:0001569=ISS, GO:0048859=IEA, GO:0005576=IEA, GO:0042981=IEA, GO:0048663=ISS, GO:0060840=IEA, GO:0007398=IEA, GO:0045059=ISS, GO:0048557=IEA, GO:0007596=IEA, GO:0014003=IEA, GO:0060463=IEA, GO:0035116=IEA, GO:0007442=IEA, GO:0045060=ISS, GO:0030901=ISS, GO:0048754=ISS, GO:0030900=ISS, GO:0035115=IEA, GO:0030902=ISS, GO:0060516=IEA, GO:0001570=ISS, GO:0046638=ISS, GO:0001656=ISS, GO:0033089=ISS, GO:0007389=ISS, GO:0001658=ISS, GO:0045109=IEA, GO:0001755=ISS, GO:0048538=ISS, GO:0030010=IEA, GO:0007228=ISS, GO:0007224=ISS, GO:0046639=IEA, GO:0007405=ISS, GO:0009880=TAS, GO:0001947=ISS, GO:0016015=NAS, GO:0030539=ISS, GO:0001948=IEA, GO:0007411=ISS, GO:0061189=IDA, GO:0006508=IEA, GO:0051781=IDA, GO:0072136=ISS, GO:0071285=IEA, GO:0060685=IEA, GO:0033077=ISS, GO:0030336=ISS, GO:0021938=IEA, GO:0007417=ISS, GO:0060769=IEA, GO:2000729=ISS, GO:0007418=TAS, GO:0006897=IEA, GO:0061053=ISS, GO:0043237=ISS, GO:0060174=IEA, GO:0045121=ISS, GO:0072001=IEP, GO:0008233=IEA, GO:0045596=ISS, GO:0060484=IEA, GO:0045893=IDA, GO:0042733=ISS, GO:0008284=IDA, GO:0060428=IEA, GO:0005886=IEA, GO:0030324=ISS, GO:0007267=ISS, GO:0030326=ISS, GO:0009953=ISS, GO:0032435=IEA, GO:0005539=IEA, GO:0009952=IEA, GO:0060020=IEA, GO:0060021=IEA, GO:0030850=ISS, GO:0090090=IEA, GO:0060783=IEA, GO:0060782=IEA, GO:0008209=ISS, GO:0002052=IEA, GO:0006915=IEA, GO:0033092=ISS, GO:0043369=IDA, GO:0031012=IEA, GO:2000062=ISS, GO:0031016=IEA, GO:2000063=ISS, GO:0048714=IEA, GO:0090370=ISS, GO:0048617=IEA, GO:2000357=ISS, GO:2000358=ISS} Bergmann glial cell differentiation, CD4-positive or CD8-positive, alpha-beta T cell lineage commitment, T cell differentiation in thymus, androgen metabolic process, anterior/posterior pattern specification, apoptotic process, artery development, axon guidance, blood coagulation, branching involved in salivary gland morphogenesis, branching involved in ureteric bud morphogenesis, branching morphogenesis of an epithelial tube, bud outgrowth involved in lung branching, camera-type eye development, canonical Wnt receptor signaling pathway, cell development, cell fate specification, cell-cell signaling, cellular response to lithium ion, central nervous system development, determination of left/right asymmetry in lateral mesoderm, dorsal/ventral neural tube patterning, dorsal/ventral pattern formation, ectoderm development, embryo development, embryonic digestive tract morphogenesis, embryonic digit morphogenesis, embryonic foregut morphogenesis, embryonic forelimb morphogenesis, embryonic hindlimb morphogenesis, embryonic limb morphogenesis, embryonic pattern specification, embryonic skeletal system development, endocytosis, epithelial cell proliferation involved in salivary gland morphogenesis, epithelial-mesenchymal signaling involved in prostate gland development, establishment of cell polarity, forebrain development, formation of anatomical boundary, hair follicle morphogenesis, heart development, heart looping, hindbrain development, hindgut morphogenesis, inner ear development, intein-mediated protein splicing, intermediate filament organization, left lung development, limb bud formation, lung development, lung epithelium development, lung lobe morphogenesis, lung-associated mesenchyme development, lymphoid progenitor cell differentiation, male genitalia development, mesenchymal cell proliferation involved in lung development, mesenchymal smoothened signaling pathway involved in prostate gland development, metanephric mesenchymal cell proliferation involved in metanephros development, metanephros development, midbrain development, multicellular organismal development, multicellular structure septum development, myoblast differentiation, myotube differentiation, negative regulation of T cell proliferation, negative regulation of alpha-beta T cell differentiation, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cell differentiation, negative regulation of cell migration, negative regulation of cholesterol efflux, negative regulation of kidney smooth muscle cell differentiation, negative regulation of proteasomal ubiquitin-dependent protein catabolic process, negative regulation of transcription elongation from RNA polymerase II promoter, negative regulation of ureter smooth muscle cell differentiation, negative thymic T cell selection, neural crest cell migration, neuroblast proliferation, neuron fate commitment, odontogenesis of dentin-containing tooth, oligodendrocyte development, organ formation, osteoblast development, palate development, pancreas development, pattern specification process, patterning of blood vessels, positive regulation of T cell differentiation in thymus, positive regulation of Wnt receptor signaling pathway, positive regulation of alpha-beta T cell differentiation, positive regulation of cell division, positive regulation of cell proliferation, positive regulation of epithelial cell proliferation involved in prostate gland development, positive regulation of hh target transcription factor activity, positive regulation of immature T cell proliferation in thymus, positive regulation of kidney smooth muscle cell differentiation, positive regulation of mesenchymal cell proliferation involved in ureter development, positive regulation of neuroblast proliferation, positive regulation of oligodendrocyte differentiation, positive regulation of protein import into nucleus, positive regulation of sclerotome development, positive regulation of skeletal muscle cell proliferation, positive regulation of skeletal muscle tissue development, positive regulation of smoothened signaling pathway, positive regulation of striated muscle cell differentiation, positive regulation of transcription, DNA-dependent, positive regulation of ureter smooth muscle cell differentiation, positive thymic T cell selection, primary prostatic bud elongation, prostate epithelial cord elongation, prostate gland development, protein localization to nucleus, proteolysis, regulation of apoptotic process, regulation of cell proliferation, regulation of mesenchymal cell proliferation involved in prostate gland development, regulation of odontogenesis, regulation of prostatic bud formation, regulation of proteolysis, renal system development, right lung development, salivary gland cavitation, skin development, smoothened signaling pathway, smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation, somite development, spinal cord dorsal/ventral patterning, stem cell development, telencephalon regionalization, thymus development, thyroid gland development, trachea morphogenesis, vasculogenesis, ventral midline development cell surface, extracellular matrix, extracellular region, extracellular space, membrane raft, nucleus, plasma membrane calcium ion binding, glycoprotein binding, glycosaminoglycan binding, laminin-1 binding, morphogen activity, patched binding, peptidase activity, protein binding, signal transducer activity, zinc ion binding Human UniProtKB:Q62226 SHISA2 UniProtKB UniProtKB {GO:0005789=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q6UWI4 Protein shisa-2 homolog protein 20130413 {GO:0005789=IEA, GO:0007275=IEA, GO:0016021=IEA} multicellular organismal development endoplasmic reticulum membrane, integral to membrane Human UniProtKB-SubCell:SL-0097 SHISA5 GOC UniProtKB {GO:0005515=PMID:15064722, GO:0007165=PMID:12761501, GO:0031965=GO_REF:0000039, GO:0005783=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0006915=GO_REF:0000019, GO:0004871=PMID:12761501, GO:0016021=GO_REF:0000037, GO:0006917=GO_REF:0000019, GO:0005635=GO_REF:0000019, GO:0043123=PMID:12761501} Q8N114 Protein shisa-5 protein 20130413 {GO:0005515=IPI, GO:0007165=IMP, GO:0031965=IEA, GO:0005783=IEA, GO:0005789=IEA, GO:0006915=IEA, GO:0004871=IMP, GO:0016021=IEA, GO:0006917=IEA, GO:0005635=IEA, GO:0043123=IMP} apoptotic process, induction of apoptosis, positive regulation of I-kappaB kinase/NF-kappaB cascade, signal transduction endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, nuclear envelope, nuclear membrane protein binding, signal transducer activity Human SHKBP1 InterPro UniProtKB {GO:0051260=GO_REF:0000002} Q8TBC3 SH3KBP1-binding protein 1 protein 20130413 {GO:0051260=IEA} protein homooligomerization Human InterPro:IPR003131 SHMT1 HPA UniProtKB {GO:0008168=GO_REF:0000038, GO:0006767=Reactome:REACT_11238, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0004372=Reactome:REACT_11159, GO:0042803=PMID:9753690, GO:0019264=GO_REF:0000019, GO:0005829=Reactome:REACT_11159, GO:0042802=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000052, GO:0051289=GO_REF:0000019, GO:0045329=Reactome:REACT_2125, GO:0046655=Reactome:REACT_11167, GO:0008242=GO_REF:0000002, GO:0051262=PMID:9753690, GO:0008732=GO_REF:0000019, GO:0035999=GO_REF:0000041, GO:0006766=Reactome:REACT_11193, GO:0030170=PMID:17482557, GO:0006544=GO_REF:0000002, GO:0009113=PMID:11516159, GO:0006563=GO_REF:0000002, GO:0016597=GO_REF:0000019, GO:0006565=PMID:17482557} P34896 Serine hydroxymethyltransferase, cytosolic protein 20101115 {GO:0008168=IEA, GO:0006767=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0004372=TAS, GO:0042803=IDA, GO:0019264=IEA, GO:0005829=TAS, GO:0042802=IEA, GO:0005739=IEA, GO:0034641=TAS, GO:0005737=IDA, GO:0051289=IEA, GO:0045329=TAS, GO:0046655=TAS, GO:0008242=IEA, GO:0051262=IDA, GO:0008732=IEA, GO:0035999=IEA, GO:0006766=TAS, GO:0030170=IDA, GO:0006544=IEA, GO:0009113=IDA, GO:0006563=IEA, GO:0016597=IEA, GO:0006565=IDA} L-serine catabolic process, L-serine metabolic process, carnitine biosynthetic process, cellular nitrogen compound metabolic process, folic acid metabolic process, glycine biosynthetic process from serine, glycine metabolic process, protein homotetramerization, protein tetramerization, purine nucleobase biosynthetic process, small molecule metabolic process, tetrahydrofolate interconversion, vitamin metabolic process, water-soluble vitamin metabolic process cytoplasm, cytosol, mitochondrion, nucleus L-allo-threonine aldolase activity, amino acid binding, glycine hydroxymethyltransferase activity, identical protein binding, methyltransferase activity, omega peptidase activity, protein homodimerization activity, pyridoxal phosphate binding Human SHMT2 HPA UniProtKB {GO:0042645=PMID:18063578, GO:0008284=GO_REF:0000019, GO:0008168=GO_REF:0000037, GO:0005743=PMID:21876188, GO:0008732=GO_REF:0000019, GO:0004372=PMID:8505317, GO:0042802=GO_REF:0000019, GO:0019264=GO_REF:0000019, GO:0035999=GO_REF:0000041, GO:0005739=GO_REF:0000052, GO:0005758=GO_REF:0000019, GO:0051289=GO_REF:0000019, GO:0003682=PMID:18063578, GO:0005759=PMID:21876188, GO:0030170=GO_REF:0000002, GO:0015630=GO_REF:0000052, GO:0006544=GO_REF:0000002, GO:0006564=GO_REF:0000019, GO:0006563=GO_REF:0000002, GO:0006730=PMID:11516159, GO:0016597=GO_REF:0000019} P34897 Serine hydroxymethyltransferase, mitochondrial protein 20100326 {GO:0042645=IDA, GO:0008284=IEA, GO:0008168=IEA, GO:0005743=IDA, GO:0008732=IEA, GO:0004372=IDA, GO:0042802=IEA, GO:0019264=IEA, GO:0035999=IEA, GO:0005739=IDA, GO:0005758=IEA, GO:0051289=IEA, GO:0003682=IDA, GO:0005759=IDA, GO:0030170=IEA, GO:0015630=IDA, GO:0006544=IEA, GO:0006564=IEA, GO:0006563=IEA, GO:0006730=IDA, GO:0016597=IEA} L-serine biosynthetic process, L-serine metabolic process, glycine biosynthetic process from serine, glycine metabolic process, one-carbon metabolic process, positive regulation of cell proliferation, protein homotetramerization, tetrahydrofolate interconversion microtubule cytoskeleton, mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial matrix, mitochondrial nucleoid, mitochondrion L-allo-threonine aldolase activity, amino acid binding, chromatin binding, glycine hydroxymethyltransferase activity, identical protein binding, methyltransferase activity, pyridoxal phosphate binding Human SHOC2 UniProtKB UniProtKB {GO:0005737=PMID:19684605, GO:0019888=PMID:16630891, GO:0008543=PMID:9618511, GO:0000164=PMID:16630891, GO:0019903=PMID:16630891, GO:0005634=PMID:19684605, GO:0046579=PMID:16630891, GO:0007265=PMID:9674433} Q9UQ13 Leucine-rich repeat protein SHOC-2 protein 20090826 {GO:0005737=IDA, GO:0019888=TAS, GO:0008543=NAS, GO:0000164=IDA, GO:0019903=IDA, GO:0005634=IDA, GO:0046579=IMP, GO:0007265=NAS} Ras protein signal transduction, fibroblast growth factor receptor signaling pathway, positive regulation of Ras protein signal transduction cytoplasm, nucleus, protein phosphatase type 1 complex protein phosphatase binding, protein phosphatase regulator activity Human SHOX IntAct UniProtKB {GO:0005515=PMID:21262861, GO:0001501=PMID:9590292, GO:0000976=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0006366=PMID:9259282, GO:0005634=GO_REF:0000039} O15266 Short stature homeobox protein protein 20130415 {GO:0005515=IPI, GO:0001501=TAS, GO:0000976=IEA, GO:0003700=IEA, GO:0006366=TAS, GO:0005634=IEA} skeletal system development, transcription from RNA polymerase II promoter nucleus protein binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding Human UniProtKB:P35712 SHOX2 PINC UniProtKB {GO:0000976=GO_REF:0000002, GO:0060415=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0003170=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0002053=GO_REF:0000019, GO:0032330=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0030326=GO_REF:0000019, GO:0001649=GO_REF:0000019, GO:0007399=PMID:9482898, GO:0003209=GO_REF:0000019, GO:0007507=PMID:9482898, GO:0045880=GO_REF:0000019, GO:0001501=PMID:9482898, GO:0048557=GO_REF:0000019, GO:0002063=GO_REF:0000019, GO:0048743=GO_REF:0000019, GO:0060351=GO_REF:0000019, GO:0060272=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:2000172=GO_REF:0000019, GO:0050772=GO_REF:0000019} O60902 Short stature homeobox protein 2 protein 20030904 {GO:0000976=IEA, GO:0060415=IEA, GO:0003700=IEA, GO:0003170=IEA, GO:0005634=IEA, GO:0002053=IEA, GO:0032330=IEA, GO:0000122=IEA, GO:0030326=IEA, GO:0001649=IEA, GO:0007399=TAS, GO:0003209=IEA, GO:0007507=TAS, GO:0045880=IEA, GO:0001501=TAS, GO:0048557=IEA, GO:0002063=IEA, GO:0048743=IEA, GO:0060351=IEA, GO:0060272=IEA, GO:0045944=IEA, GO:2000172=IEA, GO:0050772=IEA} cardiac atrium morphogenesis, cartilage development involved in endochondral bone morphogenesis, chondrocyte development, embryonic digestive tract morphogenesis, embryonic limb morphogenesis, embryonic skeletal joint morphogenesis, heart development, heart valve development, muscle tissue morphogenesis, negative regulation of transcription from RNA polymerase II promoter, nervous system development, osteoblast differentiation, positive regulation of axonogenesis, positive regulation of mesenchymal cell proliferation, positive regulation of skeletal muscle fiber development, positive regulation of smoothened signaling pathway, positive regulation of transcription from RNA polymerase II promoter, regulation of branching morphogenesis of a nerve, regulation of chondrocyte differentiation, skeletal system development nucleus sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding Human SHPK UniProtKB UniProtKB {GO:0050277=PMID:19413330, GO:0016310=PMID:19413330, GO:0005737=GO_REF:0000024, GO:0071222=PMID:22682222, GO:0005975=PMID:19413330, GO:0043030=GO_REF:0000024, GO:0050727=GO_REF:0000024, GO:0071353=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0035963=GO_REF:0000024, GO:0009052=GO_REF:0000024} Q9UHJ6 Sedoheptulokinase protein 20120924 {GO:0050277=IDA, GO:0016310=IDA, GO:0005737=ISS, GO:0071222=IDA, GO:0005975=IDA, GO:0043030=ISS, GO:0050727=ISS, GO:0071353=ISS, GO:0005524=IEA, GO:0035963=ISS, GO:0009052=ISS} carbohydrate metabolic process, cellular response to interleukin-13, cellular response to interleukin-4, cellular response to lipopolysaccharide, pentose-phosphate shunt, non-oxidative branch, phosphorylation, regulation of inflammatory response, regulation of macrophage activation cytoplasm ATP binding, sedoheptulokinase activity Human UniProtKB:Q9D5J6 SHPRH InterPro UniProtKB {GO:0016567=GO_REF:0000041, GO:0006281=GO_REF:0000037, GO:0016874=GO_REF:0000037, GO:0004386=GO_REF:0000002, GO:0006334=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0000786=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0003677=GO_REF:0000002} Q5JT88 E3 ubiquitin-protein ligase SHPRH protein 20130413 {GO:0016567=IEA, GO:0006281=IEA, GO:0016874=IEA, GO:0004386=IEA, GO:0006334=IEA, GO:0008270=IEA, GO:0005634=IEA, GO:0003676=IEA, GO:0000786=IEA, GO:0005524=IEA, GO:0003677=IEA} DNA repair, nucleosome assembly, protein ubiquitination nucleosome, nucleus ATP binding, DNA binding, helicase activity, ligase activity, nucleic acid binding, zinc ion binding Human InterPro:IPR001650 SHQ1 HPA UniProtKB {GO:0005515=PMID:19383767, GO:0005737=GO_REF:0000052, GO:0043065=PMID:20663920, GO:0015030=PMID:19383767, GO:0022618=PMID:19383767, GO:2000233=PMID:20663920, GO:0005730=GO_REF:0000052, GO:0005654=PMID:19383767, GO:0005634=GO_REF:0000052, GO:0005829=GO_REF:0000039} Q6PI26 Protein SHQ1 homolog protein 20111111 {GO:0005515=IPI, GO:0005737=IDA, GO:0043065=IDA, GO:0015030=IDA, GO:0022618=IDA, GO:2000233=IDA, GO:0005730=IDA, GO:0005654=IDA, GO:0005634=IDA, GO:0005829=IEA} negative regulation of rRNA processing, positive regulation of apoptotic process, ribonucleoprotein complex assembly Cajal body, cytoplasm, cytosol, nucleolus, nucleoplasm, nucleus protein binding Human SHROOM1 UniProtKB UniProtKB {GO:0000902=PMID:16684770, GO:0005737=GO_REF:0000037, GO:0051015=PMID:16684770, GO:0005874=GO_REF:0000037, GO:0016460=PMID:16684770, GO:0051017=PMID:16684770} Q2M3G4 Protein Shroom1 protein 20070912 {GO:0000902=ISS, GO:0005737=IEA, GO:0051015=ISS, GO:0005874=IEA, GO:0016460=ISS, GO:0051017=ISS} actin filament bundle assembly, cell morphogenesis cytoplasm, microtubule, myosin II complex actin filament binding Human UniProtKB:Q5SX79 SHROOM2 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0008013=PMID:16684770, GO:0005886=GO_REF:0000024, GO:0032438=GO_REF:0000024, GO:0048593=GO_REF:0000024, GO:0043583=GO_REF:0000024, GO:0032401=GO_REF:0000024, GO:0043296=GO_REF:0000019, GO:0030835=GO_REF:0000019, GO:0016324=GO_REF:0000024, GO:0051015=PMID:16684770, GO:0005913=PMID:16684770, GO:0002089=GO_REF:0000024, GO:0043482=GO_REF:0000024, GO:0043025=GO_REF:0000019, GO:0043010=GO_REF:0000024, GO:0005856=GO_REF:0000024, GO:0005938=GO_REF:0000019, GO:0051017=PMID:16684770, GO:0008057=GO_REF:0000024, GO:0005874=GO_REF:0000037, GO:0019904=GO_REF:0000019, GO:0045176=GO_REF:0000024, GO:0003779=GO_REF:0000024, GO:0045217=GO_REF:0000019, GO:0000902=PMID:16684770, GO:0015280=PMID:7795590, GO:0031941=GO_REF:0000019, GO:0016477=GO_REF:0000024, GO:0007420=GO_REF:0000024, GO:0030864=PMID:16684770, GO:0005923=GO_REF:0000024} Q13796 Protein Shroom2 protein 20130415 {GO:0005515=IPI, GO:0008013=ISS, GO:0005886=ISS, GO:0032438=ISS, GO:0048593=ISS, GO:0043583=ISS, GO:0032401=ISS, GO:0043296=IEA, GO:0030835=IEA, GO:0016324=ISS, GO:0051015=ISS, GO:0005913=ISS, GO:0002089=ISS, GO:0043482=ISS, GO:0043025=IEA, GO:0043010=ISS, GO:0005856=ISS, GO:0005938=IEA, GO:0051017=ISS, GO:0008057=ISS, GO:0005874=IEA, GO:0019904=IEA, GO:0045176=ISS, GO:0003779=ISS, GO:0045217=IEA, GO:0000902=IDA, GO:0015280=TAS, GO:0031941=IEA, GO:0016477=ISS, GO:0007420=ISS, GO:0030864=IDA, GO:0005923=ISS} actin filament bundle assembly, apical protein localization, brain development, camera-type eye development, camera-type eye morphogenesis, cell migration, cell morphogenesis, cell-cell junction maintenance, cellular pigment accumulation, ear development, establishment of melanosome localization, eye pigment granule organization, lens morphogenesis in camera-type eye, melanosome organization, negative regulation of actin filament depolymerization apical junction complex, apical plasma membrane, cell cortex, cell-cell adherens junction, cortical actin cytoskeleton, cytoskeleton, filamentous actin, microtubule, neuronal cell body, plasma membrane, tight junction actin binding, actin filament binding, beta-catenin binding, ligand-gated sodium channel activity, protein binding, protein domain specific binding Human UniProtKB:P16333 SHROOM3 HGNC UniProtKB {GO:0007389=GO_REF:0000024, GO:0030036=GO_REF:0000019, GO:0008360=GO_REF:0000019, GO:0005874=GO_REF:0000037, GO:0001843=GO_REF:0000019, GO:0045176=GO_REF:0000024, GO:0003779=GO_REF:0000019, GO:0000902=GO_REF:0000024, GO:0002066=GO_REF:0000019, GO:0043296=GO_REF:0000024, GO:0005737=GO_REF:0000037, GO:0016324=GO_REF:0000024, GO:0005912=GO_REF:0000024, GO:0043482=GO_REF:0000024, GO:0005856=GO_REF:0000024} Q8TF72 Protein Shroom3 protein 20070906 {GO:0007389=ISS, GO:0030036=IEA, GO:0008360=IEA, GO:0005874=IEA, GO:0001843=IEA, GO:0045176=ISS, GO:0003779=IEA, GO:0000902=ISS, GO:0002066=IEA, GO:0043296=ISS, GO:0005737=IEA, GO:0016324=ISS, GO:0005912=ISS, GO:0043482=ISS, GO:0005856=ISS} actin cytoskeleton organization, apical protein localization, cell morphogenesis, cellular pigment accumulation, columnar/cuboidal epithelial cell development, neural tube closure, pattern specification process, regulation of cell shape adherens junction, apical junction complex, apical plasma membrane, cytoplasm, cytoskeleton, microtubule actin binding Human UniProtKB:Q27IV2 SI Reactome UniProtKB {GO:0004574=GO_REF:0000003, GO:0005794=PMID:1717481, GO:0004575=Reactome:REACT_9409, GO:0005886=Reactome:REACT_9479, GO:0005975=Reactome:REACT_474, GO:0044281=Reactome:REACT_111217, GO:0004553=GO_REF:0000002, GO:0005903=PMID:1717481, GO:0016324=GO_REF:0000039, GO:0030246=GO_REF:0000002, GO:0044245=Reactome:REACT_9472, GO:0016021=GO_REF:0000037, GO:0004558=Reactome:REACT_9479} P14410 Sucrase-isomaltase, intestinal protein 20061103 {GO:0004574=IEA, GO:0005794=TAS, GO:0004575=TAS, GO:0005886=TAS, GO:0005975=TAS, GO:0044281=TAS, GO:0004553=IEA, GO:0005903=TAS, GO:0016324=IEA, GO:0030246=IEA, GO:0044245=TAS, GO:0016021=IEA, GO:0004558=TAS} carbohydrate metabolic process, polysaccharide digestion, small molecule metabolic process Golgi apparatus, apical plasma membrane, brush border, integral to membrane, plasma membrane alpha-glucosidase activity, carbohydrate binding, hydrolase activity, hydrolyzing O-glycosyl compounds, oligo-1,6-glucosidase activity, sucrose alpha-glucosidase activity Human SIAH1 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0006511=GO_REF:0000002, GO:0004842=GO_REF:0000024, GO:0005886=GO_REF:0000019, GO:0030877=PMID:16085652, GO:0005634=GO_REF:0000024, GO:0007283=GO_REF:0000037, GO:0051402=GO_REF:0000024, GO:0009653=PMID:9403064, GO:0005829=Reactome:REACT_22137, GO:0031648=GO_REF:0000019, GO:0030163=PMID:11389840, GO:0005737=PMID:9334332, GO:0042787=GO_REF:0000024, GO:0007411=Reactome:REACT_18266, GO:0006508=PMID:9334332, GO:0043065=PMID:21185211, GO:0006915=PMID:9403064, GO:0007275=GO_REF:0000002, GO:0008022=PMID:11389840, GO:0007399=PMID:9334332, GO:0007049=GO_REF:0000037, GO:0008270=PMID:16085652, GO:0043161=GO_REF:0000024, GO:0005769=GO_REF:0000019} Q8IUQ4 E3 ubiquitin-protein ligase SIAH1 protein 20130415 {GO:0005515=IPI, GO:0006511=IEA, GO:0004842=ISS, GO:0005886=IEA, GO:0030877=IDA, GO:0005634=ISS, GO:0007283=IEA, GO:0051402=ISS, GO:0009653=TAS, GO:0005829=TAS, GO:0031648=IEA, GO:0030163=IDA, GO:0005737=TAS, GO:0042787=ISS, GO:0007411=TAS, GO:0006508=TAS, GO:0043065=IDA, GO:0006915=TAS, GO:0007275=IEA, GO:0008022=IPI, GO:0007399=TAS, GO:0007049=IEA, GO:0008270=IDA, GO:0043161=ISS, GO:0005769=IEA} anatomical structure morphogenesis, apoptotic process, axon guidance, cell cycle, multicellular organismal development, nervous system development, neuron apoptotic process, positive regulation of apoptotic process, proteasomal ubiquitin-dependent protein catabolic process, protein catabolic process, protein destabilization, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, proteolysis, spermatogenesis, ubiquitin-dependent protein catabolic process beta-catenin destruction complex, cytoplasm, cytosol, early endosome, nucleus, plasma membrane protein C-terminus binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q99836 SIAH2 IntAct UniProtKB {GO:0005515=PMID:21586138, GO:2001237=PMID:21586138, GO:0006511=GO_REF:0000002, GO:0043005=GO_REF:0000019, GO:0043066=PMID:21586138, GO:0004842=GO_REF:0000002, GO:0007264=PMID:10207103, GO:0003714=PMID:10207103, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000002, GO:0005829=Reactome:REACT_22224, GO:0005737=PMID:10207103, GO:0007049=GO_REF:0000037, GO:0007411=Reactome:REACT_18266, GO:0043025=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0031396=GO_REF:0000019, GO:0044257=PMID:12952940, GO:0043154=PMID:21586138, GO:0090090=PMID:12952940, GO:0005769=GO_REF:0000019, GO:0031624=GO_REF:0000019} O43255 E3 ubiquitin-protein ligase SIAH2 protein 20130415 {GO:0005515=IPI, GO:2001237=IMP, GO:0006511=IEA, GO:0043005=IEA, GO:0043066=IMP, GO:0004842=IEA, GO:0007264=TAS, GO:0003714=TAS, GO:0005634=IEA, GO:0007275=IEA, GO:0005829=TAS, GO:0005737=TAS, GO:0007049=IEA, GO:0007411=TAS, GO:0043025=IEA, GO:0008270=IEA, GO:0031396=IEA, GO:0044257=IGI, GO:0043154=IMP, GO:0090090=IGI, GO:0005769=IEA, GO:0031624=IEA} axon guidance, cell cycle, cellular protein catabolic process, multicellular organismal development, negative regulation of apoptotic process, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of extrinsic apoptotic signaling pathway, regulation of protein ubiquitination, small GTPase mediated signal transduction, ubiquitin-dependent protein catabolic process cytoplasm, cytosol, early endosome, neuron projection, neuronal cell body, nucleus protein binding, transcription corepressor activity, ubiquitin conjugating enzyme binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q7Z6J0 SIGIRR HGNC UniProtKB {GO:0005515=PMID:12925853, GO:0007165=GO_REF:0000002, GO:0001960=GO_REF:0000024, GO:0016020=PMID:10346978, GO:0045079=GO_REF:0000024, GO:0031665=PMID:15866876, GO:0006953=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0043433=PMID:12925853} Q6IA17 Single Ig IL-1-related receptor protein 20051111 {GO:0005515=IPI, GO:0007165=IEA, GO:0001960=ISS, GO:0016020=IMP, GO:0045079=ISS, GO:0031665=TAS, GO:0006953=ISS, GO:0016021=IEA, GO:0043433=IMP} acute-phase response, negative regulation of chemokine biosynthetic process, negative regulation of cytokine-mediated signaling pathway, negative regulation of lipopolysaccharide-mediated signaling pathway, negative regulation of sequence-specific DNA binding transcription factor activity, signal transduction integral to membrane, membrane protein binding Human SIGLEC1 UniProtKB UniProtKB {GO:0016337=PMID:11133773, GO:0006954=PMID:11133773, GO:0007160=PMID:11133773, GO:0005886=GO_REF:0000039, GO:0030246=PMID:11133773, GO:0005576=GO_REF:0000039, GO:0016021=PMID:11133773, GO:0006897=GO_REF:0000037} Q9BZZ2 Sialoadhesin protein 20030404 {GO:0016337=NAS, GO:0006954=NAS, GO:0007160=NAS, GO:0005886=IEA, GO:0030246=NAS, GO:0005576=IEA, GO:0016021=NAS, GO:0006897=IEA} cell-cell adhesion, cell-matrix adhesion, endocytosis, inflammatory response extracellular region, integral to membrane, plasma membrane carbohydrate binding Human SIGLEC10 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037} Q96LC7 Sialic acid-binding Ig-like lectin 10 protein 20130413 {GO:0005886=IEA, GO:0005576=IEA, GO:0016021=IEA, GO:0007155=IEA} cell adhesion extracellular region, integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 SIGLEC11 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037} Q96RL6 Sialic acid-binding Ig-like lectin 11 protein 20130413 {GO:0016021=IEA, GO:0007155=IEA} cell adhesion integral to membrane Human UniProtKB-KW:KW-0812 SIGLEC12 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037} Q96PQ1 Sialic acid-binding Ig-like lectin 12 protein 20130413 {GO:0016021=IEA, GO:0007155=IEA} cell adhesion integral to membrane Human UniProtKB-KW:KW-0812 SIGLEC14 Reactome UniProtKB {GO:0005886=Reactome:REACT_147732, GO:0045087=Reactome:REACT_6802, GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037} Q08ET2 Sialic acid-binding Ig-like lectin 14 protein 20130301 {GO:0005886=TAS, GO:0045087=TAS, GO:0016021=IEA, GO:0007155=IEA} cell adhesion, innate immune response integral to membrane, plasma membrane Human SIGLEC5 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037} O15389 Sialic acid-binding Ig-like lectin 5 protein 20130413 {GO:0016021=IEA, GO:0007155=IEA} cell adhesion integral to membrane Human UniProtKB-KW:KW-0812 SIGLEC6 PINC UniProtKB {GO:0016020=PMID:9465907, GO:0005887=PMID:9465907, GO:0007267=PMID:9465907, GO:0005576=GO_REF:0000039, GO:0007155=GO_REF:0000037} O43699 Sialic acid-binding Ig-like lectin 6 protein 20030904 {GO:0016020=TAS, GO:0005887=TAS, GO:0007267=TAS, GO:0005576=IEA, GO:0007155=IEA} cell adhesion, cell-cell signaling extracellular region, integral to plasma membrane, membrane Human SIGLEC7 PINC UniProtKB {GO:0005887=PMID:10567377, GO:0030246=PMID:10567377, GO:0004872=PMID:10499918, GO:0007155=GO_REF:0000037} Q9Y286 Sialic acid-binding Ig-like lectin 7 protein 20030904 {GO:0005887=TAS, GO:0030246=TAS, GO:0004872=TAS, GO:0007155=IEA} cell adhesion integral to plasma membrane carbohydrate binding, receptor activity Human SIGMAR1 PINC UniProtKB {GO:0006696=GO_REF:0000002, GO:0005811=GO_REF:0000039, GO:0008219=GO_REF:0000037, GO:0000247=GO_REF:0000002, GO:0030054=GO_REF:0000039, GO:0005783=GO_REF:0000002, GO:0005637=GO_REF:0000039, GO:0005635=PMID:9341151, GO:0004985=GO_REF:0000019, GO:0007399=GO_REF:0000019, GO:0030426=GO_REF:0000039, GO:0005640=GO_REF:0000039, GO:0043523=PMID:21842496, GO:0005887=PMID:8954936, GO:0008144=PMID:8954936, GO:0006869=GO_REF:0000037, GO:0005789=GO_REF:0000039, GO:0016021=PMID:9453537} Q99720 Sigma non-opioid intracellular receptor 1 protein 20030904 {GO:0006696=IEA, GO:0005811=IEA, GO:0008219=IEA, GO:0000247=IEA, GO:0030054=IEA, GO:0005783=IEA, GO:0005637=IEA, GO:0005635=IDA, GO:0004985=IEA, GO:0007399=IEA, GO:0030426=IEA, GO:0005640=IEA, GO:0043523=IMP, GO:0005887=TAS, GO:0008144=TAS, GO:0006869=IEA, GO:0005789=IEA, GO:0016021=TAS} cell death, ergosterol biosynthetic process, lipid transport, nervous system development, regulation of neuron apoptotic process cell junction, endoplasmic reticulum, endoplasmic reticulum membrane, growth cone, integral to membrane, integral to plasma membrane, lipid particle, nuclear envelope, nuclear inner membrane, nuclear outer membrane C-8 sterol isomerase activity, drug binding, opioid receptor activity Human SIK1 BHF-UCL UniProtKB {GO:0005515=PMID:16306228, GO:0042826=GO_REF:0000019, GO:0032792=GO_REF:0000024, GO:0010830=GO_REF:0000024, GO:0005634=PMID:16306228, GO:0007243=PMID:14976552, GO:0005829=GO_REF:0000019, GO:0071889=PMID:18348280, GO:0008140=GO_REF:0000024, GO:0005737=PMID:16306228, GO:0046777=PMID:18348280, GO:2000210=PMID:19622832, GO:0055007=GO_REF:0000024, GO:0045721=GO_REF:0000024, GO:0010868=GO_REF:0000024, GO:0000287=PMID:14976552, GO:0019901=PMID:18348280, GO:0043276=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0005524=PMID:14976552, GO:0007346=GO_REF:0000024, GO:0007049=GO_REF:0000037, GO:0004674=PMID:18348280, GO:0002028=GO_REF:0000024, GO:0045595=GO_REF:0000024, GO:0006468=PMID:14976552} P57059 Serine/threonine-protein kinase SIK1 protein 20121121 {GO:0005515=IPI, GO:0042826=IEA, GO:0032792=ISS, GO:0010830=ISS, GO:0005634=IDA, GO:0007243=IDA, GO:0005829=IEA, GO:0071889=IDA, GO:0008140=ISS, GO:0005737=IDA, GO:0046777=IDA, GO:2000210=IMP, GO:0055007=ISS, GO:0045721=ISS, GO:0010868=ISS, GO:0000287=IDA, GO:0019901=IPI, GO:0043276=IEA, GO:0000122=IEA, GO:0005524=IDA, GO:0007346=ISS, GO:0007049=IEA, GO:0004674=IDA, GO:0002028=ISS, GO:0045595=ISS, GO:0006468=IDA} anoikis, cardiac muscle cell differentiation, cell cycle, intracellular protein kinase cascade, negative regulation of CREB transcription factor activity, negative regulation of gluconeogenesis, negative regulation of transcription from RNA polymerase II promoter, negative regulation of triglyceride biosynthetic process, positive regulation of anoikis, protein autophosphorylation, protein phosphorylation, regulation of cell differentiation, regulation of mitotic cell cycle, regulation of myotube differentiation, regulation of sodium ion transport cytoplasm, cytosol, nucleus 14-3-3 protein binding, ATP binding, cAMP response element binding protein binding, histone deacetylase binding, magnesium ion binding, protein binding, protein kinase binding, protein serine/threonine kinase activity Human SIK2 HPA UniProtKB {GO:0008286=GO_REF:0000019, GO:0005737=GO_REF:0000024, GO:0005794=GO_REF:0000052, GO:0046777=PMID:18348280, GO:0000287=PMID:14976552, GO:0004674=PMID:18348280, GO:0046626=GO_REF:0000024, GO:0006468=PMID:14976552, GO:0005634=GO_REF:0000019, GO:0005524=PMID:14976552, GO:0007243=PMID:14976552} Q9H0K1 Serine/threonine-protein kinase SIK2 protein 20090616 {GO:0008286=IEA, GO:0005737=ISS, GO:0005794=IDA, GO:0046777=IDA, GO:0000287=IDA, GO:0004674=IDA, GO:0046626=ISS, GO:0006468=IDA, GO:0005634=IEA, GO:0005524=IDA, GO:0007243=IDA} insulin receptor signaling pathway, intracellular protein kinase cascade, protein autophosphorylation, protein phosphorylation, regulation of insulin receptor signaling pathway Golgi apparatus, cytoplasm, nucleus ATP binding, magnesium ion binding, protein serine/threonine kinase activity Human SIK3 IntAct UniProtKB {GO:0005515=PMID:16306228, GO:0005737=GO_REF:0000039, GO:0000287=PMID:14976552, GO:0004672=GO_REF:0000002, GO:0004674=PMID:14976552, GO:0006468=PMID:14976552, GO:0005524=PMID:14976552} Q9Y2K2 Serine/threonine-protein kinase SIK3 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0000287=IDA, GO:0004672=IEA, GO:0004674=IDA, GO:0006468=IDA, GO:0005524=IDA} protein phosphorylation cytoplasm ATP binding, magnesium ion binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB:P63104 SIKE1 HPA UniProtKB {GO:0005515=PMID:18782753, GO:0045087=Reactome:REACT_6802, GO:0005925=GO_REF:0000052, GO:0043231=GO_REF:0000052, GO:0005829=Reactome:REACT_25079} Q9BRV8 Suppressor of IKBKE 1 protein 20111111 {GO:0005515=IPI, GO:0045087=TAS, GO:0005925=IDA, GO:0043231=IDA, GO:0005829=TAS} innate immune response cytosol, focal adhesion, intracellular membrane-bounded organelle protein binding Human SIL1 UniProtKB UniProtKB {GO:0006457=PMID:11101517, GO:0005783=PMID:11101517, GO:0005788=GO_REF:0000039, GO:0051082=PMID:11101517, GO:0006886=PMID:11101517} Q9H173 Nucleotide exchange factor SIL1 protein 20040806 {GO:0006457=NAS, GO:0005783=NAS, GO:0005788=IEA, GO:0051082=NAS, GO:0006886=NAS} intracellular protein transport, protein folding endoplasmic reticulum, endoplasmic reticulum lumen unfolded protein binding Human SIM1 UniProtKB UniProtKB {GO:0001657=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0046982=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0004871=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0007399=GO_REF:0000037} P81133 Single-minded homolog 1 protein 20130413 {GO:0001657=IEA, GO:0003700=IEA, GO:0046982=IEA, GO:0005634=IEA, GO:0004871=IEA, GO:0003677=IEA, GO:0030154=IEA, GO:0006351=IEA, GO:0007399=IEA} cell differentiation, nervous system development, transcription, DNA-dependent, ureteric bud development nucleus DNA binding, protein heterodimerization activity, sequence-specific DNA binding transcription factor activity, signal transducer activity Human UniProtKB-SubCell:SL-0191 SIM2 HPA UniProtKB {GO:0009880=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0046982=GO_REF:0000019, GO:0030324=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000122=GO_REF:0000019, GO:0004871=GO_REF:0000002, GO:0003677=GO_REF:0000019, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0007399=GO_REF:0000037} Q14190 Single-minded homolog 2 protein 20101115 {GO:0009880=IEA, GO:0003700=IEA, GO:0046982=IEA, GO:0030324=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0000122=IEA, GO:0004871=IEA, GO:0003677=IEA, GO:0030154=IEA, GO:0006351=IEA, GO:0007399=IEA} cell differentiation, embryonic pattern specification, lung development, negative regulation of transcription from RNA polymerase II promoter, nervous system development, transcription, DNA-dependent nucleolus, nucleus DNA binding, protein heterodimerization activity, sequence-specific DNA binding transcription factor activity, signal transducer activity NOT Human SIN3A BHF-UCL UniProtKB {GO:0005515=PMID:21258344, GO:0003700=GO_REF:0000019, GO:0005634=PMID:22783022, GO:0002218=PMID:22783022, GO:0044281=Reactome:REACT_111217, GO:2000678=PMID:22783022, GO:1900181=PMID:22783022, GO:0032403=GO_REF:0000019, GO:1901675=PMID:22783022, GO:0016580=PMID:22783022, GO:0017053=GO_REF:0000019, GO:0071333=GO_REF:0000019, GO:0000785=GO_REF:0000019, GO:0031937=PMID:22783022, GO:0044255=Reactome:REACT_22279, GO:0001103=GO_REF:0000019, GO:0001102=PMID:22783022, GO:0005667=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0001106=GO_REF:0000019, GO:0003714=PMID:19641626, GO:0007568=GO_REF:0000019, GO:0005730=GO_REF:0000039, GO:0010243=GO_REF:0000019, GO:0043619=GO_REF:0000019, GO:0051329=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0006260=GO_REF:0000019, GO:0051595=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0002230=PMID:22783022, GO:0003682=GO_REF:0000019, GO:0000776=GO_REF:0000019, GO:0005654=Reactome:REACT_25186, GO:0034613=GO_REF:0000019, GO:0045892=GO_REF:0000024} Q96ST3 Paired amphipathic helix protein Sin3a protein 20121122 {GO:0005515=IPI, GO:0003700=IEA, GO:0005634=IDA, GO:0002218=IMP, GO:0044281=TAS, GO:2000678=IMP, GO:1900181=IMP, GO:0032403=IEA, GO:1901675=IMP, GO:0016580=NAS, GO:0017053=IEA, GO:0071333=IEA, GO:0000785=IEA, GO:0031937=IMP, GO:0044255=TAS, GO:0001103=IEA, GO:0001102=IPI, GO:0005667=IEA, GO:0043066=IEA, GO:0001106=IEA, GO:0003714=RCA, GO:0007568=IEA, GO:0005730=IEA, GO:0010243=IEA, GO:0043619=IEA, GO:0051329=IEA, GO:0003677=IEA, GO:0001701=IEA, GO:0006260=IEA, GO:0051595=IEA, GO:0007596=TAS, GO:0002230=IMP, GO:0003682=IEA, GO:0000776=IEA, GO:0005654=TAS, GO:0034613=IEA, GO:0045892=ISS} DNA replication, activation of innate immune response, aging, blood coagulation, cellular lipid metabolic process, cellular protein localization, cellular response to glucose stimulus, in utero embryonic development, interphase of mitotic cell cycle, negative regulation of apoptotic process, negative regulation of histone H3-K27 acetylation, negative regulation of protein localization to nucleus, negative regulation of transcription regulatory region DNA binding, negative regulation of transcription, DNA-dependent, positive regulation of chromatin silencing, positive regulation of defense response to virus by host, regulation of transcription from RNA polymerase II promoter in response to oxidative stress, response to methylglyoxal, response to organic nitrogen, small molecule metabolic process Sin3 complex, chromatin, kinetochore, nucleolus, nucleoplasm, nucleus, transcription factor complex, transcriptional repressor complex DNA binding, RNA polymerase II activating transcription factor binding, RNA polymerase II repressing transcription factor binding, RNA polymerase II transcription corepressor activity, chromatin binding, protein binding, protein complex binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human SIN3B Reactome UniProtKB {GO:0005515=PMID:12670868, GO:0001741=GO_REF:0000019, GO:0000806=GO_REF:0000019, GO:0006355=GO_REF:0000002, GO:0000805=GO_REF:0000019, GO:0003714=GO_REF:0000019, GO:0005634=GO_REF:0000024, GO:0044281=Reactome:REACT_111217, GO:0006351=GO_REF:0000037, GO:0048738=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0007519=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0030849=GO_REF:0000019, GO:0005654=Reactome:REACT_19283, GO:0045892=GO_REF:0000019, GO:0044255=Reactome:REACT_22279} O75182 Paired amphipathic helix protein Sin3b protein 20130301 {GO:0005515=IPI, GO:0001741=IEA, GO:0000806=IEA, GO:0006355=IEA, GO:0000805=IEA, GO:0003714=IEA, GO:0005634=ISS, GO:0044281=TAS, GO:0006351=IEA, GO:0048738=IEA, GO:0005737=IEA, GO:0007519=IEA, GO:0003682=IEA, GO:0030849=IEA, GO:0005654=TAS, GO:0045892=IEA, GO:0044255=TAS} cardiac muscle tissue development, cellular lipid metabolic process, negative regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, skeletal muscle tissue development, small molecule metabolic process, transcription, DNA-dependent X chromosome, XY body, Y chromosome, autosome, cytoplasm, nucleoplasm, nucleus chromatin binding, protein binding, transcription corepressor activity Human SIPA1 GOC UniProtKB {GO:0005515=PMID:21988832, GO:0051056=GO_REF:0000002, GO:0048471=GO_REF:0000039, GO:0030308=PMID:9183624, GO:0008283=PMID:9346962, GO:0005634=PMID:9183624, GO:0032854=PMID:9346962, GO:0045786=PMID:7799964, GO:0005829=Reactome:REACT_23811, GO:0012505=GO_REF:0000039, GO:0043547=PMID:9346962, GO:0035556=PMID:9346962, GO:0007165=PMID:9346962, GO:0007162=PMID:10373454, GO:0046582=PMID:9346962, GO:0016020=GO_REF:0000037, GO:0007010=PMID:12059963, GO:0051726=GO_REF:0000019, GO:0005096=PMID:9346962} Q96FS4 Signal-induced proliferation-associated protein 1 protein 20130413 {GO:0005515=IPI, GO:0051056=IEA, GO:0048471=IEA, GO:0030308=NAS, GO:0008283=TAS, GO:0005634=IC, GO:0032854=NAS, GO:0045786=NAS, GO:0005829=TAS, GO:0012505=IEA, GO:0043547=TAS, GO:0035556=NAS, GO:0007165=TAS, GO:0007162=NAS, GO:0046582=NAS, GO:0016020=IEA, GO:0007010=NAS, GO:0051726=IEA, GO:0005096=TAS} cell proliferation, cytoskeleton organization, intracellular signal transduction, negative regulation of cell adhesion, negative regulation of cell cycle, negative regulation of cell growth, positive regulation of GTPase activity, positive regulation of Rap GTPase activity, regulation of cell cycle, regulation of small GTPase mediated signal transduction, signal transduction cytosol, endomembrane system, membrane, nucleus, perinuclear region of cytoplasm GTPase activator activity, Rap GTPase activator activity, protein binding Human SIPA1L1 UniProtKB UniProtKB {GO:0051056=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0031532=GO_REF:0000024, GO:0048013=GO_REF:0000024, GO:0005886=GO_REF:0000037, GO:0014069=GO_REF:0000024, GO:0032861=GO_REF:0000024, GO:0005575=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000037, GO:0043197=GO_REF:0000024, GO:0046875=GO_REF:0000019, GO:0048167=GO_REF:0000024, GO:0045211=GO_REF:0000037, GO:0061001=GO_REF:0000024, GO:0050770=GO_REF:0000024, GO:0032317=GO_REF:0000024, GO:0005096=GO_REF:0000037} O43166 Signal-induced proliferation-associated 1-like protein 1 protein 20110818 {GO:0051056=IEA, GO:0030054=IEA, GO:0031532=ISS, GO:0048013=ISS, GO:0005886=IEA, GO:0014069=ISS, GO:0032861=ISS, GO:0005575=ND, GO:0008150=ND, GO:0003674=ND, GO:0005737=IEA, GO:0043197=ISS, GO:0046875=IEA, GO:0048167=ISS, GO:0045211=IEA, GO:0061001=ISS, GO:0050770=ISS, GO:0032317=ISS, GO:0005096=IEA} actin cytoskeleton reorganization, activation of Rap GTPase activity, biological_process, ephrin receptor signaling pathway, regulation of Rap GTPase activity, regulation of axonogenesis, regulation of dendritic spine morphogenesis, regulation of small GTPase mediated signal transduction, regulation of synaptic plasticity cell junction, cellular_component, cytoplasm, dendritic spine, plasma membrane, postsynaptic density, postsynaptic membrane GTPase activator activity, ephrin receptor binding, molecular_function Human UniProtKB:Q8C0T5 SIPA1L2 UniProtKB UniProtKB {GO:0051056=GO_REF:0000002, GO:0005096=GO_REF:0000037} Q9P2F8 Signal-induced proliferation-associated 1-like protein 2 protein 20130413 {GO:0051056=IEA, GO:0005096=IEA} regulation of small GTPase mediated signal transduction GTPase activator activity Human UniProtKB-KW:KW-0343 SIPA1L3 UniProtKB UniProtKB {GO:0051056=GO_REF:0000002, GO:0005096=GO_REF:0000037} O60292 Signal-induced proliferation-associated 1-like protein 3 protein 20130413 {GO:0051056=IEA, GO:0005096=IEA} regulation of small GTPase mediated signal transduction GTPase activator activity Human UniProtKB-KW:KW-0343 SIRPA Reactome UniProtKB {GO:0017124=GO_REF:0000037, GO:0005886=Reactome:REACT_24015, GO:0016020=PMID:9062191, GO:0007596=Reactome:REACT_604, GO:0016021=GO_REF:0000037, GO:0050900=Reactome:REACT_12051, GO:0007155=PMID:9070220} P78324 Tyrosine-protein phosphatase non-receptor type substrate 1 protein 20130301 {GO:0017124=IEA, GO:0005886=TAS, GO:0016020=TAS, GO:0007596=TAS, GO:0016021=IEA, GO:0050900=TAS, GO:0007155=TAS} blood coagulation, cell adhesion, leukocyte migration integral to membrane, membrane, plasma membrane SH3 domain binding Human SIRPB1 UniProtKB UniProtKB {GO:0005515=PMID:10940905, GO:0007165=PMID:9062191, GO:0005886=Reactome:REACT_23798, GO:0005887=PMID:9062191, GO:0045087=Reactome:REACT_6802, GO:0016021=GO_REF:0000037, GO:0007166=PMID:9062191} Q5TFQ8 Signal-regulatory protein beta-1 isoform 3 protein 20130413 {GO:0005515=IPI, GO:0007165=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0045087=TAS, GO:0016021=IEA, GO:0007166=TAS} cell surface receptor signaling pathway, innate immune response, signal transduction integral to membrane, integral to plasma membrane, plasma membrane protein binding Human UniProtKB-KW:KW-0812 SIRPD UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q9H106 Signal-regulatory protein delta protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 SIRPG IntAct UniProtKB {GO:0005515=PMID:15383453, GO:0008284=PMID:15383453, GO:0022409=PMID:15383453, GO:0008285=PMID:9062191, GO:0005886=Reactome:REACT_23927, GO:0007267=PMID:9062191, GO:0050900=Reactome:REACT_12051, GO:0035556=PMID:9062191, GO:0016020=PMID:15383453, GO:0007596=Reactome:REACT_604, GO:0050870=PMID:15383453, GO:0016021=GO_REF:0000037, GO:0007155=GO_REF:0000037} Q9P1W8 Signal-regulatory protein gamma protein 20130415 {GO:0005515=IPI, GO:0008284=IDA, GO:0022409=IDA, GO:0008285=TAS, GO:0005886=TAS, GO:0007267=TAS, GO:0050900=TAS, GO:0035556=TAS, GO:0016020=IDA, GO:0007596=TAS, GO:0050870=IDA, GO:0016021=IEA, GO:0007155=IEA} blood coagulation, cell adhesion, cell-cell signaling, intracellular signal transduction, leukocyte migration, negative regulation of cell proliferation, positive regulation of T cell activation, positive regulation of cell proliferation, positive regulation of cell-cell adhesion integral to membrane, membrane, plasma membrane protein binding Human UniProtKB:Q08722 SIRT1 HPA UniProtKB {GO:0005515=PMID:12006491, GO:0030308=PMID:17505061, GO:0032071=PMID:19934257, GO:0007283=GO_REF:0000019, GO:0034979=PMID:11672523, GO:0045348=PMID:21890893, GO:2000757=PMID:20100829, GO:0042127=PMID:12006491, GO:0043398=PMID:12535671, GO:0031937=PMID:15469825, GO:0051019=PMID:20027304, GO:0016239=PMID:18296641, GO:0042632=GO_REF:0000024, GO:0032868=GO_REF:0000024, GO:0034983=PMID:15469825, GO:0031393=GO_REF:0000024, GO:0005719=PMID:15469825, GO:0003714=GO_REF:0000024, GO:0071479=GO_REF:0000024, GO:0018394=PMID:18004385, GO:0043280=PMID:19047049, GO:0042771=PMID:20100829, GO:0005720=PMID:15469825, GO:0006281=PMID:17317627, GO:0007517=GO_REF:0000037, GO:0000731=GO_REF:0000024, GO:0006642=GO_REF:0000024, GO:0032007=PMID:20169165, GO:0016567=PMID:21841822, GO:0005637=PMID:15469825, GO:0005634=GO_REF:0000052, GO:0005635=PMID:15469825, GO:0045739=PMID:19934257, GO:0043433=PMID:17505061, GO:0046872=GO_REF:0000037, GO:0010875=GO_REF:0000024, GO:0000720=PMID:21149730, GO:0042393=PMID:15469825, GO:0080134=PMID:19934257, GO:0070857=GO_REF:0000024, GO:0000183=PMID:18485871, GO:2000774=PMID:18687677, GO:0002821=PMID:21890893, GO:2000773=PMID:20203304, GO:0009267=GO_REF:0000024, GO:0016575=PMID:12006491, GO:0055089=GO_REF:0000024, GO:0071456=PMID:20620956, GO:0043425=PMID:12535671, GO:0042981=PMID:11672522, GO:0032088=PMID:15152190, GO:0051097=PMID:18203716, GO:2000111=GO_REF:0000024, GO:0006974=PMID:18203716, GO:0006260=PMID:17317627, GO:0042326=PMID:17612497, GO:0007346=PMID:15692560, GO:0035098=PMID:15684044, GO:0034391=GO_REF:0000024, GO:0043161=PMID:21841822, GO:2000655=PMID:17505061, GO:0000790=PMID:17505061, GO:0070301=PMID:20027304, GO:0045599=GO_REF:0000024, GO:0006364=GO_REF:0000037, GO:0070403=GO_REF:0000002, GO:0010906=GO_REF:0000024, GO:0003950=PMID:17456799, GO:0042802=PMID:15469825, GO:0071356=PMID:15152190, GO:0033158=PMID:18203716, GO:0006979=PMID:14976264, GO:0043124=PMID:17680780, GO:2000481=PMID:18687677, GO:2000480=PMID:20203304, GO:0017136=PMID:12006491, GO:0007569=PMID:11672523, GO:0019904=GO_REF:0000019, GO:0019213=PMID:18203716, GO:0060766=PMID:17505061, GO:0033553=PMID:18485871, GO:0001542=GO_REF:0000019, GO:0000122=PMID:12535671, GO:0033558=PMID:20027304, GO:0050872=GO_REF:0000024, GO:0005654=PMID:16079181, GO:0019899=GO_REF:0000019, GO:0045892=PMID:11672523, GO:0006344=PMID:15469825, GO:0051898=PMID:21149730, GO:0000012=PMID:20097625, GO:0006343=PMID:15469825, GO:0008284=PMID:21807113, GO:0006342=PMID:10381378, GO:0001678=GO_REF:0000024, GO:0006346=PMID:21947282, GO:0035358=GO_REF:0000024, GO:0035356=GO_REF:0000024, GO:0006471=PMID:17456799, GO:0031648=GO_REF:0000024, GO:0002039=PMID:11672523, GO:0005737=GO_REF:0000052, GO:0045944=PMID:21807113, GO:0004407=PMID:20027304, GO:0006476=PMID:11672523, GO:0046969=GO_REF:0000024, GO:0030512=GO_REF:0000024, GO:0070932=PMID:17505061, GO:0043066=PMID:17317627, GO:0043065=PMID:19047049, GO:0008630=GO_REF:0000019, GO:0005730=PMID:15469825, GO:0046628=PMID:21241768, GO:0001525=PMID:20620956, GO:0008022=PMID:18203716, GO:0006351=GO_REF:0000037, GO:0016605=PMID:12006491, GO:0019048=GO_REF:0000037, GO:0001934=GO_REF:0000024, GO:0043518=PMID:11672523, GO:0005677=PMID:18485871} Q96EB6 NAD-dependent protein deacetylase sirtuin-1 protein 20080205 {GO:0005515=IPI, GO:0030308=IMP, GO:0032071=IMP, GO:0007283=IEA, GO:0034979=IMP, GO:0045348=IDA, GO:2000757=IDA, GO:0042127=IMP, GO:0043398=IPI, GO:0031937=IMP, GO:0051019=IPI, GO:0016239=IDA, GO:0042632=ISS, GO:0032868=ISS, GO:0034983=IDA, GO:0031393=ISS, GO:0005719=IDA, GO:0003714=ISS, GO:0071479=ISS, GO:0018394=IMP, GO:0043280=IMP, GO:0042771=IMP, GO:0005720=IDA, GO:0006281=TAS, GO:0007517=IEA, GO:0000731=ISS, GO:0006642=ISS, GO:0032007=IMP, GO:0016567=IDA, GO:0005637=IDA, GO:0005634=IDA, GO:0005635=IDA, GO:0045739=IMP, GO:0043433=IMP, GO:0046872=IEA, GO:0010875=ISS, GO:0000720=IMP, GO:0042393=IPI, GO:0080134=IDA, GO:0070857=ISS, GO:0000183=IDA, GO:2000774=IDA, GO:0002821=IDA, GO:2000773=IDA, GO:0009267=ISS, GO:0016575=IDA, GO:0055089=ISS, GO:0071456=IMP, GO:0043425=IPI, GO:0042981=ISS, GO:0032088=IDA, GO:0051097=IDA, GO:2000111=ISS, GO:0006974=IDA, GO:0006260=TAS, GO:0042326=IMP, GO:0007346=IDA, GO:0035098=IDA, GO:0034391=ISS, GO:0043161=IMP, GO:2000655=IMP, GO:0000790=IDA, GO:0070301=IDA, GO:0045599=ISS, GO:0006364=IEA, GO:0070403=IEA, GO:0010906=ISS, GO:0003950=TAS, GO:0042802=IPI, GO:0071356=IDA, GO:0033158=IMP, GO:0006979=IDA, GO:0043124=IDA, GO:2000481=IMP, GO:2000480=IDA, GO:0017136=IDA, GO:0007569=TAS, GO:0019904=IEA, GO:0019213=IDA, GO:0060766=IMP, GO:0033553=IDA, GO:0001542=IEA, GO:0000122=IDA, GO:0033558=IDA, GO:0050872=ISS, GO:0005654=IDA, GO:0019899=IEA, GO:0045892=IDA, GO:0006344=IMP, GO:0051898=IMP, GO:0000012=IMP, GO:0006343=IDA, GO:0008284=IMP, GO:0006342=TAS, GO:0001678=ISS, GO:0006346=TAS, GO:0035358=ISS, GO:0035356=ISS, GO:0006471=TAS, GO:0031648=ISS, GO:0002039=IPI, GO:0005737=IDA, GO:0045944=IDA, GO:0004407=IDA, GO:0006476=IMP, GO:0046969=ISS, GO:0030512=ISS, GO:0070932=IMP, GO:0043066=TAS, GO:0043065=IMP, GO:0008630=IEA, GO:0005730=IDA, GO:0046628=IDA, GO:0001525=IDA, GO:0008022=IPI, GO:0006351=IEA, GO:0016605=IDA, GO:0019048=IEA, GO:0001934=ISS, GO:0043518=IDA, GO:0005677=IDA} DNA repair, DNA replication, DNA synthesis involved in DNA repair, angiogenesis, cell aging, cellular glucose homeostasis, cellular response to hydrogen peroxide, cellular response to hypoxia, cellular response to ionizing radiation, cellular response to starvation, cellular response to tumor necrosis factor, cellular triglyceride homeostasis, cholesterol homeostasis, chromatin silencing, chromatin silencing at rDNA, establishment of chromatin silencing, fatty acid homeostasis, histone H3 deacetylation, histone deacetylation, intrinsic apoptotic signaling pathway in response to DNA damage, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, maintenance of chromatin silencing, methylation-dependent chromatin silencing, muscle organ development, negative regulation of DNA damage response, signal transduction by p53 class mediator, negative regulation of I-kappaB kinase/NF-kappaB cascade, negative regulation of NF-kappaB transcription factor activity, negative regulation of TOR signaling cascade, negative regulation of androgen receptor signaling pathway, negative regulation of apoptotic process, negative regulation of cAMP-dependent protein kinase activity, negative regulation of cell growth, negative regulation of cellular response to testosterone stimulus, negative regulation of cellular senescence, negative regulation of fat cell differentiation, negative regulation of helicase activity, negative regulation of peptidyl-lysine acetylation, negative regulation of phosphorylation, negative regulation of prostaglandin biosynthetic process, negative regulation of protein kinase B signaling cascade, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, negative regulation of transforming growth factor beta receptor signaling pathway, ovulation from ovarian follicle, peptidyl-lysine acetylation, peptidyl-lysine deacetylation, positive regulation of DNA repair, positive regulation of MHC class II biosynthetic process, positive regulation of adaptive immune response, positive regulation of apoptotic process, positive regulation of cAMP-dependent protein kinase activity, positive regulation of cell proliferation, positive regulation of cellular senescence, positive regulation of cholesterol efflux, positive regulation of chromatin silencing, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of insulin receptor signaling pathway, positive regulation of macroautophagy, positive regulation of macrophage apoptotic process, positive regulation of protein phosphorylation, positive regulation of transcription from RNA polymerase II promoter, proteasomal ubiquitin-dependent protein catabolic process, protein ADP-ribosylation, protein deacetylation, protein destabilization, protein ubiquitination, pyrimidine dimer repair by nucleotide-excision repair, rRNA processing, regulation of apoptotic process, regulation of bile acid biosynthetic process, regulation of cell proliferation, regulation of endodeoxyribonuclease activity, regulation of glucose metabolic process, regulation of mitotic cell cycle, regulation of peroxisome proliferator activated receptor signaling pathway, regulation of protein import into nucleus, translocation, regulation of response to stress, regulation of smooth muscle cell apoptotic process, response to DNA damage stimulus, response to insulin stimulus, response to oxidative stress, single strand break repair, spermatogenesis, transcription, DNA-dependent, triglyceride mobilization, virus-host interaction, white fat cell differentiation ESC/E(Z) complex, PML body, chromatin silencing complex, cytoplasm, nuclear chromatin, nuclear envelope, nuclear euchromatin, nuclear heterochromatin, nuclear inner membrane, nucleolus, nucleoplasm, nucleus, rDNA heterochromatin HLH domain binding, NAD+ ADP-ribosyltransferase activity, NAD+ binding, NAD-dependent histone deacetylase activity, NAD-dependent histone deacetylase activity (H3-K9 specific), NAD-dependent protein deacetylase activity, bHLH transcription factor binding, deacetylase activity, enzyme binding, histone binding, histone deacetylase activity, identical protein binding, metal ion binding, mitogen-activated protein kinase binding, p53 binding, protein C-terminus binding, protein binding, protein deacetylase activity, protein domain specific binding, transcription corepressor activity Human SIRT2 BHF-UCL UniProtKB {GO:0005515=PMID:23201684, GO:0043130=PMID:12697818, GO:0006342=PMID:12697818, GO:0042826=PMID:12620231, GO:0006348=PMID:11427894, GO:0007096=PMID:12697818, GO:0016458=PMID:10381378, GO:0070403=PMID:11427894, GO:0003950=PMID:17456799, GO:0006471=PMID:17456799, GO:0005737=PMID:12697818, GO:0000183=PMID:11427894, GO:0006476=PMID:17172643, GO:0035035=PMID:12887892, GO:0016575=PMID:12697818, GO:0017136=PMID:11427894, GO:0005874=PMID:12620231, GO:0033558=PMID:17172643, GO:0045843=PMID:12887892, GO:0042325=PMID:12697818, GO:0007067=GO_REF:0000037, GO:0042903=PMID:12620231, GO:0090042=GO_REF:0000019, GO:0051775=PMID:12887892, GO:0043161=PMID:21841822, GO:0008270=PMID:11427894, GO:0045892=PMID:12887892, GO:0008134=PMID:15126506, GO:0051301=GO_REF:0000037, GO:0005677=PMID:12697818} Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 protein 20080911 {GO:0005515=IPI, GO:0043130=IDA, GO:0006342=NAS, GO:0042826=IPI, GO:0006348=NAS, GO:0007096=NAS, GO:0016458=NAS, GO:0070403=IDA, GO:0003950=TAS, GO:0006471=TAS, GO:0005737=IDA, GO:0000183=NAS, GO:0006476=IDA, GO:0035035=IPI, GO:0016575=TAS, GO:0017136=IDA, GO:0005874=IDA, GO:0033558=IDA, GO:0045843=IDA, GO:0042325=NAS, GO:0007067=IEA, GO:0042903=IDA, GO:0090042=IEA, GO:0051775=NAS, GO:0043161=IMP, GO:0008270=IDA, GO:0045892=IDA, GO:0008134=IPI, GO:0051301=IEA, GO:0005677=NAS} cell division, chromatin silencing, chromatin silencing at rDNA, chromatin silencing at telomere, gene silencing, histone deacetylation, mitosis, negative regulation of striated muscle tissue development, negative regulation of transcription, DNA-dependent, proteasomal ubiquitin-dependent protein catabolic process, protein ADP-ribosylation, protein deacetylation, regulation of exit from mitosis, regulation of phosphorylation, response to redox state, tubulin deacetylation chromatin silencing complex, cytoplasm, microtubule NAD+ ADP-ribosyltransferase activity, NAD+ binding, NAD-dependent histone deacetylase activity, histone acetyltransferase binding, histone deacetylase binding, protein binding, protein deacetylase activity, transcription factor binding, tubulin deacetylase activity, ubiquitin binding, zinc ion binding NOT Human SIRT3 BHF-UCL UniProtKB {GO:0006471=PMID:17456799, GO:0009060=PMID:22309213, GO:0005515=PMID:22770219, GO:0005739=PMID:16079181, GO:0034983=PMID:22309213, GO:0016020=GO_REF:0000019, GO:0016811=GO_REF:0000002, GO:0005759=GO_REF:0000039, GO:0008270=PMID:19535340, GO:0070403=GO_REF:0000002, GO:0006476=PMID:16788062, GO:0003950=PMID:17456799} Q9NTG7 NAD-dependent protein deacetylase sirtuin-3, mitochondrial protein 20080911 {GO:0006471=TAS, GO:0009060=IMP, GO:0005515=IPI, GO:0005739=IDA, GO:0034983=IMP, GO:0016020=IEA, GO:0016811=IEA, GO:0005759=IEA, GO:0008270=IDA, GO:0070403=IEA, GO:0006476=IDA, GO:0003950=TAS} aerobic respiration, peptidyl-lysine deacetylation, protein ADP-ribosylation, protein deacetylation membrane, mitochondrial matrix, mitochondrion NAD+ ADP-ribosyltransferase activity, NAD+ binding, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides, protein binding, zinc ion binding NOT Human SIRT4 BHF-UCL UniProtKB {GO:0006471=PMID:17456799, GO:0005515=PMID:17715127, GO:0005739=PMID:16079181, GO:0006342=PMID:10381378, GO:0005759=PMID:17715127, GO:0008270=GO_REF:0000020, GO:0070403=GO_REF:0000020, GO:0046676=PMID:17715127, GO:0034979=PMID:17715127, GO:0003950=PMID:17456799} Q9Y6E7 NAD-dependent protein deacetylase sirtuin-4 protein 20080911 {GO:0006471=TAS, GO:0005515=IPI, GO:0005739=IDA, GO:0006342=TAS, GO:0005759=IDA, GO:0008270=IEA, GO:0070403=IEA, GO:0046676=IMP, GO:0034979=IDA, GO:0003950=TAS} chromatin silencing, negative regulation of insulin secretion, protein ADP-ribosylation mitochondrial matrix, mitochondrion NAD+ ADP-ribosyltransferase activity, NAD+ binding, NAD-dependent protein deacetylase activity, protein binding, zinc ion binding Human SIRT5 HPA UniProtKB {GO:0006342=PMID:10381378, GO:0070403=PMID:22076378, GO:0036049=PMID:22076378, GO:0003950=PMID:17456799, GO:0005739=GO_REF:0000052, GO:0036054=PMID:22076378, GO:0006471=PMID:17456799, GO:0005758=PMID:18680753, GO:0036055=PMID:22076378, GO:0005759=PMID:18680753, GO:0036047=PMID:22076378, GO:0008270=PMID:22076378, GO:0006476=PMID:22076378} Q9NXA8 NAD-dependent protein deacylase sirtuin-5, mitochondrial protein 20101115 {GO:0006342=TAS, GO:0070403=IDA, GO:0036049=IDA, GO:0003950=TAS, GO:0005739=IDA, GO:0036054=IDA, GO:0006471=TAS, GO:0005758=IDA, GO:0036055=IDA, GO:0005759=IDA, GO:0036047=IDA, GO:0008270=IDA, GO:0006476=IDA} chromatin silencing, peptidyl-lysine demalonylation, peptidyl-lysine desuccinylation, protein ADP-ribosylation, protein deacetylation mitochondrial intermembrane space, mitochondrial matrix, mitochondrion NAD+ ADP-ribosyltransferase activity, NAD+ binding, protein-malonyllysine demalonylase activity, protein-succinyllysine desuccinylase activity, zinc ion binding Human SIRT6 BHF-UCL UniProtKB {GO:0005515=PMID:19135889, GO:0017136=GO_REF:0000024, GO:0005730=PMID:16079181, GO:0070403=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0010569=PMID:19135889, GO:0003950=PMID:17456799, GO:0006471=PMID:17456799, GO:0003956=GO_REF:0000024, GO:0005724=PMID:18337721, GO:0008270=GO_REF:0000024, GO:0005654=PMID:16079181, GO:0046969=PMID:18337721} Q8N6T7 NAD-dependent protein deacetylase sirtuin-6 protein 20080911 {GO:0005515=IPI, GO:0017136=ISS, GO:0005730=IDA, GO:0070403=ISS, GO:0005634=ISS, GO:0010569=IDA, GO:0003950=TAS, GO:0006471=TAS, GO:0003956=ISS, GO:0005724=IDA, GO:0008270=ISS, GO:0005654=IDA, GO:0046969=IDA} protein ADP-ribosylation, regulation of double-strand break repair via homologous recombination nuclear telomeric heterochromatin, nucleolus, nucleoplasm, nucleus NAD(P)+-protein-arginine ADP-ribosyltransferase activity, NAD+ ADP-ribosyltransferase activity, NAD+ binding, NAD-dependent histone deacetylase activity, NAD-dependent histone deacetylase activity (H3-K9 specific), protein binding, zinc ion binding Human SIRT7 UniProtKB UniProtKB {GO:0005515=PMID:22722849, GO:0070932=PMID:22722849, GO:0097372=PMID:22722849, GO:0005737=GO_REF:0000039, GO:0007072=PMID:19174463, GO:0003682=PMID:22722849, GO:0009303=PMID:19174463, GO:0005730=PMID:16079181, GO:0070403=GO_REF:0000002, GO:0000122=PMID:22722849, GO:0005731=PMID:19174463, GO:0046872=GO_REF:0000037} Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 protein 20120920 {GO:0005515=IPI, GO:0070932=IDA, GO:0097372=IDA, GO:0005737=IEA, GO:0007072=IMP, GO:0003682=IDA, GO:0009303=IMP, GO:0005730=IDA, GO:0070403=IEA, GO:0000122=IDA, GO:0005731=IDA, GO:0046872=IEA} histone H3 deacetylation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of transcription on exit from mitosis, rRNA transcription cytoplasm, nucleolus, nucleolus organizer region NAD+ binding, NAD-dependent histone deacetylase activity (H3-K18 specific), chromatin binding, metal ion binding, protein binding Human UniProtKB:P28324 SIT1 HPA UniProtKB {GO:0005515=PMID:10209036, GO:0007165=PMID:10209036, GO:0005737=GO_REF:0000052, GO:0050863=PMID:10209036, GO:0005886=GO_REF:0000052, GO:0005887=PMID:11433379, GO:0005730=GO_REF:0000052, GO:0019900=PMID:10209036, GO:0042169=PMID:11433379} Q9Y3P8 Signaling threshold-regulating transmembrane adapter 1 protein 20090616 {GO:0005515=IPI, GO:0007165=TAS, GO:0005737=IDA, GO:0050863=IDA, GO:0005886=IDA, GO:0005887=TAS, GO:0005730=IDA, GO:0019900=IPI, GO:0042169=TAS} regulation of T cell activation, signal transduction cytoplasm, integral to plasma membrane, nucleolus, plasma membrane SH2 domain binding, kinase binding, protein binding Human SIVA1 GOC UniProtKB {GO:0005515=PMID:16683188, GO:0005175=PMID:9177220, GO:0005737=GO_REF:0000039, GO:0001618=GO_REF:0000024, GO:0019048=GO_REF:0000037, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006917=PMID:9177220, GO:0009615=GO_REF:0000024, GO:0046872=GO_REF:0000037} O15304 Apoptosis regulatory protein Siva protein 20130413 {GO:0005515=IPI, GO:0005175=IPI, GO:0005737=IEA, GO:0001618=ISS, GO:0019048=IEA, GO:0006915=IEA, GO:0005634=IEA, GO:0006917=IDA, GO:0009615=ISS, GO:0046872=IEA} apoptotic process, induction of apoptosis, response to virus, virus-host interaction cytoplasm, nucleus CD27 receptor binding, metal ion binding, protein binding, viral receptor activity Human UniProtKB:O54926 SIX1 HPA UniProtKB {GO:0005515=PMID:16189514, GO:0001657=GO_REF:0000024, GO:0007389=GO_REF:0000024, GO:0034504=PMID:19497856, GO:0001658=GO_REF:0000024, GO:0003700=GO_REF:0000024, GO:0044212=PMID:16670092, GO:0007605=GO_REF:0000019, GO:0048704=GO_REF:0000024, GO:0048538=GO_REF:0000024, GO:0001759=GO_REF:0000024, GO:0030878=GO_REF:0000024, GO:0048701=GO_REF:0000024, GO:0072075=GO_REF:0000024, GO:0043524=GO_REF:0000024, GO:0090191=GO_REF:0000019, GO:0048839=GO_REF:0000024, GO:0042472=GO_REF:0000024, GO:0072107=GO_REF:0000024, GO:0000122=GO_REF:0000019, GO:2000729=GO_REF:0000019, GO:0060037=GO_REF:0000019, GO:0072193=GO_REF:0000019, GO:0072095=GO_REF:0000024, GO:0007519=GO_REF:0000024, GO:0045893=GO_REF:0000024, GO:0051451=GO_REF:0000024, GO:0048699=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0032880=GO_REF:0000019, GO:0045944=PMID:15141091, GO:0030855=GO_REF:0000024, GO:0090103=GO_REF:0000019, GO:0072513=GO_REF:0000019, GO:0042474=GO_REF:0000019, GO:0090190=GO_REF:0000024, GO:0005667=GO_REF:0000024, GO:0006355=GO_REF:0000024, GO:0072172=GO_REF:0000024, GO:0071599=GO_REF:0000019, GO:0001822=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0035909=GO_REF:0000019, GO:0003677=PMID:19497856, GO:0006351=GO_REF:0000024, GO:0003151=GO_REF:0000019, GO:0043565=PMID:15141091, GO:0003682=GO_REF:0000019, GO:0045664=GO_REF:0000024, GO:0008582=GO_REF:0000019, GO:0021610=GO_REF:0000019} Q15475 Homeobox protein SIX1 protein 20101115 {GO:0005515=IPI, GO:0001657=ISS, GO:0007389=ISS, GO:0034504=IDA, GO:0001658=ISS, GO:0003700=ISS, GO:0044212=IDA, GO:0007605=IEA, GO:0048704=ISS, GO:0048538=ISS, GO:0001759=ISS, GO:0030878=ISS, GO:0048701=ISS, GO:0072075=ISS, GO:0043524=ISS, GO:0090191=IEA, GO:0048839=ISS, GO:0042472=ISS, GO:0072107=ISS, GO:0000122=IEA, GO:2000729=IEA, GO:0060037=IEA, GO:0072193=IEA, GO:0072095=ISS, GO:0007519=ISS, GO:0045893=ISS, GO:0051451=ISS, GO:0048699=ISS, GO:0005634=IDA, GO:0032880=IEA, GO:0045944=IDA, GO:0030855=ISS, GO:0090103=IEA, GO:0072513=IEA, GO:0042474=IEA, GO:0090190=ISS, GO:0005667=ISS, GO:0006355=ISS, GO:0072172=ISS, GO:0071599=IEA, GO:0001822=ISS, GO:0005730=IDA, GO:0035909=IEA, GO:0003677=IDA, GO:0006351=ISS, GO:0003151=IEA, GO:0043565=IDA, GO:0003682=IEA, GO:0045664=ISS, GO:0008582=IEA, GO:0021610=IEA} aorta morphogenesis, branching involved in ureteric bud morphogenesis, cochlea morphogenesis, embryonic cranial skeleton morphogenesis, embryonic skeletal system morphogenesis, epithelial cell differentiation, facial nerve morphogenesis, generation of neurons, inner ear development, inner ear morphogenesis, kidney development, mesonephric tubule formation, metanephric mesenchyme development, middle ear morphogenesis, myoblast migration, negative regulation of branching involved in ureteric bud morphogenesis, negative regulation of neuron apoptotic process, negative regulation of transcription from RNA polymerase II promoter, organ induction, otic vesicle development, outflow tract morphogenesis, pattern specification process, pharyngeal system development, positive regulation of branching involved in ureteric bud morphogenesis, positive regulation of mesenchymal cell proliferation involved in ureter development, positive regulation of secondary heart field cardioblast proliferation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of ureteric bud formation, protein localization to nucleus, regulation of branch elongation involved in ureteric bud branching, regulation of neuron differentiation, regulation of protein localization, regulation of synaptic growth at neuromuscular junction, regulation of transcription, DNA-dependent, sensory perception of sound, skeletal muscle tissue development, thymus development, thyroid gland development, transcription, DNA-dependent, ureter smooth muscle cell differentiation, ureteric bud development nucleolus, nucleus, transcription factor complex DNA binding, chromatin binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding Human SIX2 PINC UniProtKB {GO:0003700=GO_REF:0000019, GO:0001822=PMID:18305125, GO:0008283=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0006606=GO_REF:0000019, GO:0009653=PMID:10773454, GO:0032403=GO_REF:0000019, GO:0048701=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0003337=GO_REF:0000019, GO:0007501=GO_REF:0000019, GO:0002062=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0042474=GO_REF:0000019, GO:0045596=GO_REF:0000019} Q9NPC8 Homeobox protein SIX2 protein 20031119 {GO:0003700=IEA, GO:0001822=IMP, GO:0008283=IEA, GO:0005634=IEA, GO:0006606=IEA, GO:0009653=TAS, GO:0032403=IEA, GO:0048701=IEA, GO:0043565=IEA, GO:0003337=IEA, GO:0007501=IEA, GO:0002062=IEA, GO:0045944=IEA, GO:0042474=IEA, GO:0045596=IEA} anatomical structure morphogenesis, cell proliferation, chondrocyte differentiation, embryonic cranial skeleton morphogenesis, kidney development, mesenchymal to epithelial transition involved in metanephros morphogenesis, mesodermal cell fate specification, middle ear morphogenesis, negative regulation of cell differentiation, positive regulation of transcription from RNA polymerase II promoter, protein import into nucleus nucleus protein complex binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human SIX3 PINC UniProtKB {GO:0021536=GO_REF:0000019, GO:0060235=GO_REF:0000019, GO:0003705=GO_REF:0000019, GO:0030178=GO_REF:0000019, GO:0048512=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0006606=GO_REF:0000019, GO:0021537=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0021797=GO_REF:0000019, GO:0007420=PMID:10369266, GO:0045944=GO_REF:0000019, GO:0007601=PMID:10369266, GO:0045892=GO_REF:0000019} O95343 Homeobox protein SIX3 protein 20030904 {GO:0021536=IEA, GO:0060235=IEA, GO:0003705=IEA, GO:0030178=IEA, GO:0048512=IEA, GO:0005634=IEA, GO:0006606=IEA, GO:0021537=IEA, GO:0043565=IEA, GO:0021797=IEA, GO:0007420=TAS, GO:0045944=IEA, GO:0007601=TAS, GO:0045892=IEA} brain development, circadian behavior, diencephalon development, forebrain anterior/posterior pattern specification, lens induction in camera-type eye, negative regulation of Wnt receptor signaling pathway, negative regulation of transcription, DNA-dependent, positive regulation of transcription from RNA polymerase II promoter, protein import into nucleus, telencephalon development, visual perception nucleus RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, sequence-specific DNA binding Human SIX4 PINC UniProtKB {GO:0003700=GO_REF:0000019, GO:0042472=GO_REF:0000019, GO:0048699=GO_REF:0000019, GO:0072107=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0048538=GO_REF:0000019, GO:0009653=PMID:10640827, GO:0048701=GO_REF:0000019, GO:0072075=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0032880=GO_REF:0000019, GO:0072095=GO_REF:0000019, GO:0043524=GO_REF:0000019, GO:0007519=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0008582=GO_REF:0000019, GO:0090190=GO_REF:0000019, GO:0051451=GO_REF:0000019} Q9UIU6 Homeobox protein SIX4 protein 20031119 {GO:0003700=IEA, GO:0042472=IEA, GO:0048699=IEA, GO:0072107=IEA, GO:0005634=IEA, GO:0048538=IEA, GO:0009653=TAS, GO:0048701=IEA, GO:0072075=IEA, GO:0043565=IEA, GO:0032880=IEA, GO:0072095=IEA, GO:0043524=IEA, GO:0007519=IEA, GO:0045944=IEA, GO:0008582=IEA, GO:0090190=IEA, GO:0051451=IEA} anatomical structure morphogenesis, embryonic cranial skeleton morphogenesis, generation of neurons, inner ear morphogenesis, metanephric mesenchyme development, myoblast migration, negative regulation of neuron apoptotic process, positive regulation of branching involved in ureteric bud morphogenesis, positive regulation of transcription from RNA polymerase II promoter, positive regulation of ureteric bud formation, regulation of branch elongation involved in ureteric bud branching, regulation of protein localization, regulation of synaptic growth at neuromuscular junction, skeletal muscle tissue development, thymus development nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human SIX5 HPA UniProtKB {GO:0005515=PMID:16713569, GO:0043565=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0008285=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0002088=GO_REF:0000019, GO:0007286=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q8N196 Homeobox protein SIX5 protein 20111111 {GO:0005515=IPI, GO:0043565=IEA, GO:0005737=IDA, GO:0008285=IEA, GO:0003700=IEA, GO:0002088=IEA, GO:0007286=IEA, GO:0005634=IEA, GO:0006351=IEA} lens development in camera-type eye, negative regulation of cell proliferation, spermatid development, transcription, DNA-dependent cytoplasm, nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human SIX6 PINC UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0009887=PMID:10512683, GO:0005634=GO_REF:0000039, GO:0007601=PMID:10512683} O95475 Homeobox protein SIX6 protein 20030904 {GO:0043565=IEA, GO:0003700=IEA, GO:0009887=TAS, GO:0005634=IEA, GO:0007601=TAS} organ morphogenesis, visual perception nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human SKA1 HPA UniProtKB {GO:0008017=PMID:19289083, GO:0005515=PMID:17093495, GO:0000236=Reactome:REACT_682, GO:0005813=GO_REF:0000052, GO:0031110=PMID:19289083, GO:0005829=Reactome:REACT_150414, GO:0007067=PMID:19289083, GO:0000940=PMID:17093495, GO:0007059=PMID:19289083, GO:0015630=GO_REF:0000052, GO:0000087=Reactome:REACT_910, GO:0005876=PMID:19289083, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=PMID:17093495} Q96BD8 Spindle and kinetochore-associated protein 1 protein 20111111 {GO:0008017=IDA, GO:0005515=IPI, GO:0000236=TAS, GO:0005813=IDA, GO:0031110=IDA, GO:0005829=TAS, GO:0007067=IMP, GO:0000940=IDA, GO:0007059=IMP, GO:0015630=IDA, GO:0000087=TAS, GO:0005876=IDA, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IMP} M phase of mitotic cell cycle, cell division, chromosome segregation, mitosis, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, regulation of microtubule polymerization or depolymerization centrosome, condensed chromosome outer kinetochore, cytosol, microtubule cytoskeleton, spindle microtubule microtubule binding, protein binding Human SKA2 Reactome UniProtKB {GO:0008017=PMID:19289083, GO:0005515=PMID:19289083, GO:0000236=Reactome:REACT_682, GO:0031110=PMID:19289083, GO:0005829=Reactome:REACT_150414, GO:0000940=PMID:17093495, GO:0007067=PMID:19289083, GO:0007059=PMID:19289083, GO:0000087=Reactome:REACT_910, GO:0005876=PMID:19289083, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=PMID:17093495} Q8WVK7 Spindle and kinetochore-associated protein 2 protein 20130213 {GO:0008017=IDA, GO:0005515=IPI, GO:0000236=TAS, GO:0031110=IDA, GO:0005829=TAS, GO:0000940=IDA, GO:0007067=IMP, GO:0007059=IMP, GO:0000087=TAS, GO:0005876=IDA, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IMP} M phase of mitotic cell cycle, cell division, chromosome segregation, mitosis, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, regulation of microtubule polymerization or depolymerization condensed chromosome outer kinetochore, cytosol, spindle microtubule microtubule binding, protein binding Human SKA3 UniProtKB UniProtKB {GO:0005515=PMID:19289083, GO:0000940=PMID:19289083, GO:0007067=PMID:19289083, GO:0005737=GO_REF:0000037, GO:0007059=PMID:19289083, GO:0031110=PMID:19289083, GO:0005876=PMID:19289083, GO:0051301=GO_REF:0000037} Q8IX90 Spindle and kinetochore-associated protein 3 protein 20090422 {GO:0005515=IPI, GO:0000940=IDA, GO:0007067=IMP, GO:0005737=IEA, GO:0007059=IMP, GO:0031110=IDA, GO:0005876=IDA, GO:0051301=IEA} cell division, chromosome segregation, mitosis, regulation of microtubule polymerization or depolymerization condensed chromosome outer kinetochore, cytoplasm, spindle microtubule protein binding Human SKAP1 HPA UniProtKB {GO:0005515=PMID:19798671, GO:0050852=PMID:11909961, GO:0005886=PMID:11909961, GO:0019901=PMID:9195899, GO:0005634=GO_REF:0000052, GO:0032403=GO_REF:0000019, GO:0003823=PMID:11909961, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0045944=PMID:11909961, GO:0005070=PMID:9195899, GO:0045893=PMID:11909961, GO:0042169=PMID:9195899} Q86WV1 Src kinase-associated phosphoprotein 1 protein 20080818 {GO:0005515=IPI, GO:0050852=IMP, GO:0005886=IDA, GO:0019901=IPI, GO:0005634=IDA, GO:0032403=IEA, GO:0003823=IPI, GO:0005737=IDA, GO:0005543=IEA, GO:0045944=IMP, GO:0005070=IC, GO:0045893=IMP, GO:0042169=IDA} T cell receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent cytoplasm, nucleus, plasma membrane SH2 domain binding, SH3/SH2 adaptor activity, antigen binding, phospholipid binding, protein binding, protein complex binding, protein kinase binding Human SKAP2 Reactome UniProtKB {GO:0007165=PMID:9837776, GO:0042113=GO_REF:0000037, GO:0006461=PMID:9671755, GO:0008285=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0005886=PMID:11390434, GO:0005070=PMID:9671755, GO:0005829=Reactome:REACT_23995} O75563 Src kinase-associated phosphoprotein 2 protein 20090211 {GO:0007165=TAS, GO:0042113=IEA, GO:0006461=TAS, GO:0008285=IEA, GO:0005543=IEA, GO:0005886=IDA, GO:0005070=TAS, GO:0005829=TAS} B cell activation, negative regulation of cell proliferation, protein complex assembly, signal transduction cytosol, plasma membrane SH3/SH2 adaptor activity, phospholipid binding Human SKI BHF-UCL UniProtKB {GO:0005515=PMID:14525983, GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_12627, GO:0060041=GO_REF:0000024, GO:0046332=PMID:15107821, GO:0048593=GO_REF:0000024, GO:0070207=PMID:8514802, GO:0000166=GO_REF:0000002, GO:0017053=GO_REF:0000024, GO:0007179=PMID:14583455, GO:0031625=PMID:17510063, GO:0014902=PMID:19008232, GO:0019901=PMID:12874272, GO:0003714=PMID:12435627, GO:0019904=PMID:11441023, GO:0001843=GO_REF:0000024, GO:0048741=GO_REF:0000024, GO:0032926=PMID:14699069, GO:0000122=Reactome:REACT_121111, GO:0030509=Reactome:REACT_12034, GO:0060349=GO_REF:0000024, GO:0043388=PMID:15107821, GO:0008270=PMID:12419246, GO:0005654=Reactome:REACT_121269, GO:0043585=GO_REF:0000024, GO:0008285=PMID:11430826, GO:0008283=PMID:14583455, GO:0022011=GO_REF:0000024, GO:0048147=GO_REF:0000024, GO:0030177=PMID:14583455, GO:0005634=PMID:17510063, GO:0030326=GO_REF:0000024, GO:0060395=PMID:12874272, GO:0030514=PMID:14699069, GO:0005737=GO_REF:0000024, GO:0002089=GO_REF:0000024, GO:0009948=GO_REF:0000024, GO:0021772=GO_REF:0000024, GO:0048870=PMID:14583455, GO:0045944=GO_REF:0000024, GO:0070491=PMID:12435627, GO:0060021=GO_REF:0000024, GO:0043010=GO_REF:0000024, GO:0035019=GO_REF:0000024, GO:0030512=PMID:15312649, GO:0005667=GO_REF:0000024, GO:0042981=GO_REF:0000024, GO:0006351=GO_REF:0000024, GO:0016604=PMID:12874272, GO:0010626=PMID:15312649, GO:0045668=PMID:14699069, GO:0060325=GO_REF:0000024, GO:0016605=PMID:11430826, GO:0003682=GO_REF:0000019, GO:0046811=GO_REF:0000024} P12755 Ski oncogene protein 20110403 {GO:0005515=IPI, GO:0010467=TAS, GO:0006367=TAS, GO:0060041=ISS, GO:0046332=IPI, GO:0048593=ISS, GO:0070207=IDA, GO:0000166=IEA, GO:0017053=ISS, GO:0007179=NAS, GO:0031625=IPI, GO:0014902=IDA, GO:0019901=IPI, GO:0003714=IMP, GO:0019904=IPI, GO:0001843=ISS, GO:0048741=ISS, GO:0032926=IDA, GO:0000122=TAS, GO:0030509=TAS, GO:0060349=ISS, GO:0043388=IDA, GO:0008270=IDA, GO:0005654=TAS, GO:0043585=ISS, GO:0008285=IDA, GO:0008283=NAS, GO:0022011=ISS, GO:0048147=ISS, GO:0030177=NAS, GO:0005634=IDA, GO:0030326=ISS, GO:0060395=IDA, GO:0030514=IDA, GO:0005737=ISS, GO:0002089=ISS, GO:0009948=ISS, GO:0021772=ISS, GO:0048870=NAS, GO:0045944=ISS, GO:0070491=IPI, GO:0060021=ISS, GO:0043010=ISS, GO:0035019=ISS, GO:0030512=IGI, GO:0005667=ISS, GO:0042981=ISS, GO:0006351=ISS, GO:0016604=IDA, GO:0010626=IGI, GO:0045668=IDA, GO:0060325=ISS, GO:0016605=IDA, GO:0003682=IEA, GO:0046811=ISS} BMP signaling pathway, SMAD protein signal transduction, anterior/posterior axis specification, bone morphogenesis, camera-type eye development, camera-type eye morphogenesis, cell motility, cell proliferation, embryonic limb morphogenesis, face morphogenesis, gene expression, lens morphogenesis in camera-type eye, myelination in peripheral nervous system, myotube differentiation, negative regulation of BMP signaling pathway, negative regulation of Schwann cell proliferation, negative regulation of activin receptor signaling pathway, negative regulation of cell proliferation, negative regulation of fibroblast proliferation, negative regulation of osteoblast differentiation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transforming growth factor beta receptor signaling pathway, neural tube closure, nose morphogenesis, olfactory bulb development, palate development, positive regulation of DNA binding, positive regulation of Wnt receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, protein homotrimerization, regulation of apoptotic process, retina development in camera-type eye, skeletal muscle fiber development, somatic stem cell maintenance, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway PML body, cytoplasm, nuclear body, nucleoplasm, nucleus, transcription factor complex, transcriptional repressor complex SMAD binding, chromatin binding, histone deacetylase inhibitor activity, nucleotide binding, protein binding, protein domain specific binding, protein kinase binding, repressing transcription factor binding, transcription corepressor activity, ubiquitin protein ligase binding, zinc ion binding Human UniProtKB:Q60698 SKIL IntAct UniProtKB {GO:0005515=PMID:10049357, GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_12627, GO:0070306=GO_REF:0000019, GO:0001825=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0042981=GO_REF:0000033, GO:0046332=GO_REF:0000002, GO:0000122=Reactome:REACT_121111, GO:0006351=Reactome:REACT_121061, GO:0000166=GO_REF:0000002, GO:0003682=GO_REF:0000019, GO:0007050=GO_REF:0000019, GO:0007179=Reactome:REACT_6844, GO:0005654=Reactome:REACT_121269, GO:0045596=GO_REF:0000019, GO:0002260=GO_REF:0000019, GO:0030512=GO_REF:0000019} P12757 Ski-like protein protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0006367=TAS, GO:0070306=IEA, GO:0001825=IEA, GO:0005634=IEA, GO:0042981=IBA, GO:0046332=IEA, GO:0000122=TAS, GO:0006351=TAS, GO:0000166=IEA, GO:0003682=IEA, GO:0007050=IEA, GO:0007179=TAS, GO:0005654=TAS, GO:0045596=IEA, GO:0002260=IEA, GO:0030512=IEA} blastocyst formation, cell cycle arrest, gene expression, lens fiber cell differentiation, lymphocyte homeostasis, negative regulation of cell differentiation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transforming growth factor beta receptor signaling pathway, regulation of apoptotic process, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway nucleoplasm, nucleus SMAD binding, chromatin binding, nucleotide binding, protein binding Human UniProtKB:Q60974 SKIV2L PINC UniProtKB {GO:0004004=PMID:7610041, GO:0008026=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0004386=GO_REF:0000038, GO:0005634=GO_REF:0000039, GO:0055087=PMID:16024656, GO:0016818=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q15477 Helicase SKI2W protein 20030904 {GO:0004004=TAS, GO:0008026=IEA, GO:0003723=IEA, GO:0004386=IEA, GO:0005634=IEA, GO:0055087=IDA, GO:0016818=IEA, GO:0003676=IEA, GO:0005524=IEA} Ski complex, nucleus ATP binding, ATP-dependent RNA helicase activity, ATP-dependent helicase activity, RNA binding, helicase activity, hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, nucleic acid binding Human SKIV2L2 HPA UniProtKB {GO:0005515=PMID:17412707, GO:0008026=GO_REF:0000002, GO:0000460=PMID:17412707, GO:0000398=PMID:11991638, GO:0005730=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0071013=PMID:11991638, GO:0016818=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0000178=PMID:11719186} P42285 Superkiller viralicidic activity 2-like 2 protein 20110516 {GO:0005515=IPI, GO:0008026=IEA, GO:0000460=IMP, GO:0000398=IC, GO:0005730=IEA, GO:0005634=IDA, GO:0071013=IDA, GO:0016818=IEA, GO:0003676=IEA, GO:0005524=IEA, GO:0000178=IDA} mRNA splicing, via spliceosome, maturation of 5.8S rRNA catalytic step 2 spliceosome, exosome (RNase complex), nucleolus, nucleus ATP binding, ATP-dependent helicase activity, hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, nucleic acid binding, protein binding Human SKP1 IntAct UniProtKB {GO:0005515=PMID:22632967, GO:0031519=PMID:16943429, GO:0006511=GO_REF:0000002, GO:0035518=PMID:16943429, GO:0004842=PMID:20347421, GO:0016567=PMID:15103331, GO:0051437=Reactome:REACT_6821, GO:0031146=PMID:15103331, GO:0031145=Reactome:REACT_6828, GO:0051439=Reactome:REACT_6837, GO:0005829=Reactome:REACT_118856, GO:0000084=Reactome:REACT_899, GO:0000082=Reactome:REACT_1783, GO:0007219=Reactome:REACT_118859, GO:0016032=Reactome:REACT_6185, GO:0005654=Reactome:REACT_160209, GO:0000080=Reactome:REACT_1590, GO:0000278=Reactome:REACT_152, GO:0019005=PMID:23263282} P63208 S-phase kinase-associated protein 1 protein 20130415 {GO:0005515=IPI, GO:0031519=IDA, GO:0006511=IEA, GO:0035518=IDA, GO:0004842=IDA, GO:0016567=IDA, GO:0051437=TAS, GO:0031146=IDA, GO:0031145=TAS, GO:0051439=TAS, GO:0005829=TAS, GO:0000084=TAS, GO:0000082=TAS, GO:0007219=TAS, GO:0016032=TAS, GO:0005654=TAS, GO:0000080=TAS, GO:0000278=TAS, GO:0019005=IDA} G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, Notch signaling pathway, S phase of mitotic cell cycle, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, histone H2A monoubiquitination, mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein ubiquitination, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, ubiquitin-dependent protein catabolic process, viral reproduction PcG protein complex, SCF ubiquitin ligase complex, cytosol, nucleoplasm protein binding, ubiquitin-protein ligase activity Human UniProtKB:Q9Y3I1 SKP2 IntAct UniProtKB {GO:0000209=GO_REF:0000019, GO:0005515=PMID:12813041, GO:0004842=GO_REF:0000019, GO:0071460=GO_REF:0000019, GO:0008283=PMID:7553852, GO:0031145=Reactome:REACT_6828, GO:0048661=GO_REF:0000019, GO:0042802=PMID:22770219, GO:0005829=Reactome:REACT_9035, GO:0000084=Reactome:REACT_899, GO:0000082=Reactome:REACT_1783, GO:0000086=GO_REF:0000019, GO:0051726=GO_REF:0000019, GO:0033148=GO_REF:0000019, GO:0005654=Reactome:REACT_111194, GO:0000080=Reactome:REACT_1590, GO:0000278=Reactome:REACT_152, GO:0019005=PMID:16880511} Q13309 S-phase kinase-associated protein 2 protein 20130415 {GO:0000209=IEA, GO:0005515=IPI, GO:0004842=IEA, GO:0071460=IEA, GO:0008283=TAS, GO:0031145=TAS, GO:0048661=IEA, GO:0042802=IPI, GO:0005829=TAS, GO:0000084=TAS, GO:0000082=TAS, GO:0000086=IEA, GO:0051726=IEA, GO:0033148=IEA, GO:0005654=TAS, GO:0000080=TAS, GO:0000278=TAS, GO:0019005=IDA} G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, G2/M transition of mitotic cell cycle, S phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell proliferation, cellular response to cell-matrix adhesion, mitotic cell cycle, positive regulation of intracellular estrogen receptor signaling pathway, positive regulation of smooth muscle cell proliferation, protein polyubiquitination, regulation of cell cycle SCF ubiquitin ligase complex, cytosol, nucleoplasm identical protein binding, protein binding, ubiquitin-protein ligase activity Human UniProtKB:P61024 SLA PINC UniProtKB {GO:0005070=PMID:7543898, GO:0005768=GO_REF:0000039} Q13239 Src-like-adapter protein 20030904 {GO:0005070=TAS, GO:0005768=IEA} endosome SH3/SH2 adaptor activity Human SLA2 UniProtKB UniProtKB {GO:0005515=PMID:11891219, GO:0019724=PMID:11891219, GO:0005886=PMID:11891219, GO:0005770=GO_REF:0000019, GO:0050869=PMID:11891219, GO:0000122=PMID:11696592, GO:0050851=PMID:11696592, GO:0005737=PMID:11696592, GO:0042110=PMID:11891219, GO:0047485=PMID:11891219, GO:0005070=PMID:11891219, GO:0050776=PMID:11696592, GO:0016023=GO_REF:0000039, GO:0030522=PMID:11891219, GO:0010008=PMID:11696592, GO:0050849=PMID:11696592} Q9H6Q3 Src-like-adapter 2 protein 20040202 {GO:0005515=IPI, GO:0019724=TAS, GO:0005886=TAS, GO:0005770=IEA, GO:0050869=TAS, GO:0000122=IDA, GO:0050851=TAS, GO:0005737=TAS, GO:0042110=TAS, GO:0047485=IPI, GO:0005070=IDA, GO:0050776=NAS, GO:0016023=IEA, GO:0030522=TAS, GO:0010008=NAS, GO:0050849=IDA} B cell mediated immunity, T cell activation, antigen receptor-mediated signaling pathway, intracellular receptor signaling pathway, negative regulation of B cell activation, negative regulation of calcium-mediated signaling, negative regulation of transcription from RNA polymerase II promoter, regulation of immune response cytoplasm, cytoplasmic membrane-bounded vesicle, endosome membrane, late endosome, plasma membrane SH3/SH2 adaptor activity, protein N-terminus binding, protein binding Human SLAIN2 UniProtKB UniProtKB {GO:0005515=PMID:21646404, GO:0031116=PMID:21646404, GO:0005813=PMID:21399614, GO:0005737=GO_REF:0000037, GO:0007020=PMID:21646404, GO:0015630=PMID:21646404, GO:0031122=PMID:21646404, GO:0035371=PMID:21646404} Q9P270 SLAIN motif-containing protein 2 protein 20120110 {GO:0005515=IPI, GO:0031116=IMP, GO:0005813=IDA, GO:0005737=IEA, GO:0007020=IMP, GO:0015630=IDA, GO:0031122=IMP, GO:0035371=IDA} cytoplasmic microtubule organization, microtubule nucleation, positive regulation of microtubule polymerization centrosome, cytoplasm, microtubule cytoskeleton, microtubule plus end protein binding Human SLAMF1 IntAct UniProtKB {GO:0005515=PMID:22048310, GO:0008284=PMID:7617038, GO:0046649=GO_REF:0000002, GO:0009986=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0004872=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0003823=PMID:7617038, GO:0009897=GO_REF:0000019, GO:0004888=PMID:7617038} Q13291 Signaling lymphocytic activation molecule protein 20130415 {GO:0005515=IPI, GO:0008284=TAS, GO:0046649=IEA, GO:0009986=IEA, GO:0019048=IEA, GO:0004872=IEA, GO:0016021=IEA, GO:0003823=TAS, GO:0009897=IEA, GO:0004888=TAS} lymphocyte activation, positive regulation of cell proliferation, virus-host interaction cell surface, external side of plasma membrane, integral to membrane antigen binding, protein binding, receptor activity, transmembrane signaling receptor activity Human UniProtKB:Q786F2 SLAMF6 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0004872=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q96DU3 SLAM family member 6 protein 20130413 {GO:0005886=IEA, GO:0004872=IEA, GO:0016021=IEA} integral to membrane, plasma membrane receptor activity Human UniProtKB-SubCell:SL-0039 SLAMF7 UniProtKB UniProtKB {GO:0016020=GO_REF:0000029, GO:0030101=PMID:11698418, GO:0005886=GO_REF:0000019, GO:0042267=PMID:11698418, GO:0032814=GO_REF:0000019, GO:0004872=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0007155=PMID:11802771} Q9NQ25 SLAM family member 7 protein 20050526 {GO:0016020=NAS, GO:0030101=NAS, GO:0005886=IEA, GO:0042267=NAS, GO:0032814=IEA, GO:0004872=IEA, GO:0016021=IEA, GO:0007155=NAS} cell adhesion, natural killer cell activation, natural killer cell mediated cytotoxicity, regulation of natural killer cell activation integral to membrane, membrane, plasma membrane receptor activity Human SLBP Reactome UniProtKB {GO:0005515=PMID:15829567, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0006398=GO_REF:0000024, GO:0008334=Reactome:REACT_1364, GO:0006366=Reactome:REACT_1366, GO:0033261=PMID:19155325, GO:0033260=PMID:19155325, GO:0031124=Reactome:REACT_1768, GO:0005634=PMID:15829567, GO:0003729=PMID:16912046, GO:0005829=Reactome:REACT_1799, GO:0005737=PMID:15829567, GO:0006406=Reactome:REACT_1281, GO:0030529=PMID:10825184, GO:0005654=Reactome:REACT_1799, GO:0071204=GO_REF:0000024, GO:0051028=PMID:19155325, GO:0071207=GO_REF:0000024, GO:0071208=GO_REF:0000024} Q14493 Histone RNA hairpin-binding protein protein 20130213 {GO:0005515=IPI, GO:0010467=TAS, GO:0006369=TAS, GO:0006398=ISS, GO:0008334=TAS, GO:0006366=TAS, GO:0033261=IMP, GO:0033260=IMP, GO:0031124=TAS, GO:0005634=IDA, GO:0003729=IDA, GO:0005829=TAS, GO:0005737=IDA, GO:0006406=TAS, GO:0030529=TAS, GO:0005654=TAS, GO:0071204=ISS, GO:0051028=IDA, GO:0071207=ISS, GO:0071208=ISS} DNA replication involved in S phase, gene expression, histone mRNA 3'-end processing, histone mRNA metabolic process, mRNA 3'-end processing, mRNA export from nucleus, mRNA transport, regulation of S phase, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter cytoplasm, cytosol, histone pre-mRNA 3'end processing complex, nucleoplasm, nucleus, ribonucleoprotein complex histone pre-mRNA DCP binding, histone pre-mRNA stem-loop binding, mRNA binding, protein binding Human SLC10A1 Reactome UniProtKB {GO:0016323=GO_REF:0000019, GO:0005886=Reactome:REACT_9958, GO:0005887=PMID:8132774, GO:0015721=Reactome:REACT_11042, GO:0008508=GO_REF:0000002, GO:0006810=PMID:8132774, GO:0008206=Reactome:REACT_11040, GO:0044281=Reactome:REACT_111217} Q14973 Sodium/bile acid cotransporter protein 20130301 {GO:0016323=IEA, GO:0005886=TAS, GO:0005887=TAS, GO:0015721=TAS, GO:0008508=IEA, GO:0006810=TAS, GO:0008206=TAS, GO:0044281=TAS} bile acid and bile salt transport, bile acid metabolic process, small molecule metabolic process, transport basolateral plasma membrane, integral to plasma membrane, plasma membrane bile acid:sodium symporter activity Human SLC10A2 Reactome UniProtKB {GO:0016324=GO_REF:0000019, GO:0000502=GO_REF:0000019, GO:0005886=Reactome:REACT_10050, GO:0005887=PMID:7592981, GO:0015721=Reactome:REACT_11042, GO:0008508=GO_REF:0000002, GO:0006810=PMID:9109432, GO:0008206=Reactome:REACT_11040, GO:0005634=GO_REF:0000019, GO:0044281=Reactome:REACT_111217} Q12908 Ileal sodium/bile acid cotransporter protein 20130301 {GO:0016324=IEA, GO:0000502=IEA, GO:0005886=TAS, GO:0005887=TAS, GO:0015721=TAS, GO:0008508=IEA, GO:0006810=TAS, GO:0008206=TAS, GO:0005634=IEA, GO:0044281=TAS} bile acid and bile salt transport, bile acid metabolic process, small molecule metabolic process, transport apical plasma membrane, integral to plasma membrane, nucleus, plasma membrane, proteasome complex bile acid:sodium symporter activity Human SLC10A3 ENSEMBL UniProtKB {GO:0016020=GO_REF:0000002, GO:0008508=GO_REF:0000002, GO:0016021=GO_REF:0000029, GO:0032526=GO_REF:0000019, GO:0006814=GO_REF:0000029} Q5HY78 P3 protein protein 20130413 {GO:0016020=IEA, GO:0008508=IEA, GO:0016021=NAS, GO:0032526=IEA, GO:0006814=NAS} response to retinoic acid, sodium ion transport integral to membrane, membrane bile acid:sodium symporter activity Human Ensembl:ENSMUSP00000045150 SLC10A4 UniProtKB UniProtKB {GO:0008508=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q96EP9 Sodium/bile acid cotransporter 4 protein 20130413 {GO:0008508=IEA, GO:0016021=IEA} integral to membrane bile acid:sodium symporter activity Human UniProtKB-KW:KW-0812 SLC11A2 GOC UniProtKB {GO:0005515=PMID:18776082, GO:0005215=GO_REF:0000002, GO:0048471=PMID:10751401, GO:0005886=PMID:17932044, GO:0015078=GO_REF:0000019, GO:0005634=PMID:15880641, GO:0035434=PMID:12734107, GO:0015684=PMID:12734107, GO:0005765=PMID:10751401, GO:0006879=Reactome:REACT_25060, GO:0015295=PMID:17109629, GO:0005737=PMID:11891802, GO:0016324=PMID:15880641, GO:0005375=PMID:12734107, GO:0048821=GO_REF:0000019, GO:0070574=PMID:12662899, GO:0010039=PMID:17109629, GO:0007611=GO_REF:0000019, GO:0005773=PMID:17932044, GO:0015692=PMID:12127992, GO:0070826=PMID:11842004, GO:0009986=GO_REF:0000019, GO:0015087=GO_REF:0000019, GO:0015086=PMID:12662899, GO:0045178=PMID:15880641, GO:0045177=PMID:15880641, GO:0015093=PMID:12734107, GO:0015094=PMID:12127992, GO:0031410=PMID:15880641, GO:0055085=Reactome:REACT_19118, GO:0060586=PMID:15459009, GO:0012505=GO_REF:0000019, GO:0006783=GO_REF:0000019, GO:0005903=GO_REF:0000019, GO:0048813=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0005384=PMID:17293870, GO:0005887=GO_REF:0000019, GO:0031902=PMID:10751401, GO:0070627=GO_REF:0000019, GO:0006828=PMID:17293870, GO:0055037=PMID:15880641, GO:0071421=PMID:17293870, GO:0006825=PMID:12734107, GO:0005769=PMID:15880641} P49281 Natural resistance-associated macrophage protein 2 protein 20130413 {GO:0005515=IPI, GO:0005215=IEA, GO:0048471=IDA, GO:0005886=IMP, GO:0015078=IEA, GO:0005634=IDA, GO:0035434=IDA, GO:0015684=IDA, GO:0005765=IDA, GO:0006879=TAS, GO:0015295=IDA, GO:0005737=IDA, GO:0016324=IDA, GO:0005375=IDA, GO:0048821=IEA, GO:0070574=IDA, GO:0010039=IEP, GO:0007611=IEA, GO:0005773=IMP, GO:0015692=IDA, GO:0070826=IDA, GO:0009986=IEA, GO:0015087=IEA, GO:0015086=IDA, GO:0045178=IDA, GO:0045177=IDA, GO:0015093=IDA, GO:0015094=IDA, GO:0031410=IDA, GO:0055085=TAS, GO:0060586=IMP, GO:0012505=IEA, GO:0006783=IEA, GO:0005903=IEA, GO:0048813=IEA, GO:0016020=IEA, GO:0005384=IDA, GO:0005887=IEA, GO:0031902=IDA, GO:0070627=IEA, GO:0006828=IDA, GO:0055037=IDA, GO:0071421=IDA, GO:0006825=IDA, GO:0005769=IDA} cadmium ion transmembrane transport, cellular iron ion homeostasis, copper ion transmembrane transport, copper ion transport, dendrite morphogenesis, erythrocyte development, ferrous iron import, ferrous iron transport, heme biosynthetic process, lead ion transport, learning or memory, manganese ion transmembrane transport, manganese ion transport, multicellular organismal iron ion homeostasis, response to iron ion, transmembrane transport apical part of cell, apical plasma membrane, basal part of cell, brush border, cell surface, cytoplasm, cytoplasmic vesicle, early endosome, endomembrane system, integral to plasma membrane, late endosome membrane, lysosomal membrane, membrane, nucleus, paraferritin complex, perinuclear region of cytoplasm, plasma membrane, recycling endosome, vacuole cadmium ion transmembrane transporter activity, cobalt ion transmembrane transporter activity, copper ion transmembrane transporter activity, ferrous iron transmembrane transporter activity, hydrogen ion transmembrane transporter activity, lead ion transmembrane transporter activity, manganese ion transmembrane transporter activity, protein binding, solute:hydrogen symporter activity, transporter activity Human SLC12A1 InterPro UniProtKB {GO:0048878=GO_REF:0000019, GO:0007588=GO_REF:0000019, GO:0005215=GO_REF:0000002, GO:0005886=Reactome:REACT_19223, GO:0001822=GO_REF:0000019, GO:0015377=GO_REF:0000002, GO:0055085=GO_REF:0000002, GO:0016324=GO_REF:0000019, GO:0034220=GO_REF:0000024, GO:0016020=GO_REF:0000002, GO:0006810=PMID:8640224, GO:0016021=GO_REF:0000037, GO:0006814=GO_REF:0000037, GO:0006813=GO_REF:0000037, GO:0008511=PMID:8640224, GO:0006811=GO_REF:0000002} Q8IUN5 SLC12A1 protein protein 20130413 {GO:0048878=IEA, GO:0007588=IEA, GO:0005215=IEA, GO:0005886=TAS, GO:0001822=IEA, GO:0015377=IEA, GO:0055085=IEA, GO:0016324=IEA, GO:0034220=ISS, GO:0016020=IEA, GO:0006810=TAS, GO:0016021=IEA, GO:0006814=IEA, GO:0006813=IEA, GO:0008511=TAS, GO:0006811=IEA} chemical homeostasis, excretion, ion transmembrane transport, ion transport, kidney development, potassium ion transport, sodium ion transport, transmembrane transport, transport apical plasma membrane, integral to membrane, membrane, plasma membrane cation:chloride symporter activity, sodium:potassium:chloride symporter activity, transporter activity Human InterPro:IPR004841 SLC12A2 Reactome UniProtKB {GO:0030321=PMID:12946942, GO:0005886=Reactome:REACT_19223, GO:0015696=PMID:12946942, GO:0015377=GO_REF:0000002, GO:0060763=GO_REF:0000019, GO:0055085=Reactome:REACT_19118, GO:0016323=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0016020=PMID:7629105, GO:0035264=GO_REF:0000019, GO:0005887=PMID:7629105, GO:0050910=GO_REF:0000019, GO:0006810=PMID:7629105, GO:0051739=PMID:12946942, GO:0070634=PMID:18032481, GO:0016021=GO_REF:0000002, GO:0006814=GO_REF:0000037, GO:0006813=GO_REF:0000037, GO:0060444=GO_REF:0000019, GO:0006811=Reactome:REACT_19397, GO:0008511=PMID:7629105} P55011 Solute carrier family 12 member 2 protein 20130301 {GO:0030321=IDA, GO:0005886=TAS, GO:0015696=IDA, GO:0015377=IEA, GO:0060763=IEA, GO:0055085=TAS, GO:0016323=IEA, GO:0016324=IEA, GO:0016020=TAS, GO:0035264=IEA, GO:0005887=TAS, GO:0050910=IEA, GO:0006810=TAS, GO:0051739=IDA, GO:0070634=IDA, GO:0016021=IEA, GO:0006814=IEA, GO:0006813=IEA, GO:0060444=IEA, GO:0006811=TAS, GO:0008511=TAS} ammonium transport, branching involved in mammary gland duct morphogenesis, detection of mechanical stimulus involved in sensory perception of sound, ion transport, mammary duct terminal end bud growth, multicellular organism growth, potassium ion transport, sodium ion transport, transepithelial ammonium transport, transepithelial chloride transport, transmembrane transport, transport apical plasma membrane, basolateral plasma membrane, integral to membrane, integral to plasma membrane, membrane, plasma membrane ammonia transmembrane transporter activity, cation:chloride symporter activity, sodium:potassium:chloride symporter activity Human SLC12A3 BHF-UCL UniProtKB {GO:0005515=PMID:22406640, GO:0005215=GO_REF:0000024, GO:0005886=Reactome:REACT_19417, GO:0015378=PMID:8528245, GO:0015377=GO_REF:0000002, GO:0055085=Reactome:REACT_19118, GO:0005829=GO_REF:0000019, GO:0016324=PMID:21397062, GO:0016020=PMID:8670281, GO:0005887=PMID:8670281, GO:0006810=PMID:8670281, GO:0035725=GO_REF:0000024, GO:0016021=GO_REF:0000002, GO:0006814=GO_REF:0000024, GO:0006811=Reactome:REACT_19397} P55017 Solute carrier family 12 member 3 protein 20110426 {GO:0005515=IPI, GO:0005215=ISS, GO:0005886=TAS, GO:0015378=TAS, GO:0015377=IEA, GO:0055085=TAS, GO:0005829=IEA, GO:0016324=IDA, GO:0016020=TAS, GO:0005887=TAS, GO:0006810=TAS, GO:0035725=ISS, GO:0016021=IEA, GO:0006814=ISS, GO:0006811=TAS} ion transport, sodium ion transmembrane transport, sodium ion transport, transmembrane transport, transport apical plasma membrane, cytosol, integral to membrane, integral to plasma membrane, membrane, plasma membrane cation:chloride symporter activity, protein binding, sodium:chloride symporter activity, transporter activity Human UniProtKB:P55018 SLC12A4 Reactome UniProtKB {GO:0005886=Reactome:REACT_19385, GO:0016020=PMID:8663127, GO:0015379=GO_REF:0000002, GO:0005887=PMID:8663127, GO:0006810=PMID:8663127, GO:0016021=GO_REF:0000002, GO:0006813=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0006811=Reactome:REACT_19397, GO:0006884=PMID:9516379} Q9UP95 Solute carrier family 12 member 4 protein 20130301 {GO:0005886=TAS, GO:0016020=TAS, GO:0015379=IEA, GO:0005887=TAS, GO:0006810=TAS, GO:0016021=IEA, GO:0006813=IEA, GO:0055085=TAS, GO:0006811=TAS, GO:0006884=TAS} cell volume homeostasis, ion transport, potassium ion transport, transmembrane transport, transport integral to membrane, integral to plasma membrane, membrane, plasma membrane potassium:chloride symporter activity Human SLC12A6 Reactome UniProtKB {GO:0016323=GO_REF:0000024, GO:0005886=Reactome:REACT_19385, GO:0016020=GO_REF:0000002, GO:0015379=PMID:16048901, GO:0001525=PMID:10187864, GO:0016021=PMID:10187864, GO:0071477=PMID:16048901, GO:0006813=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0006811=Reactome:REACT_19397} Q9UHW9 Solute carrier family 12 member 6 protein 20130301 {GO:0016323=ISS, GO:0005886=TAS, GO:0016020=IEA, GO:0015379=IDA, GO:0001525=NAS, GO:0016021=NAS, GO:0071477=IDA, GO:0006813=IEA, GO:0055085=TAS, GO:0006811=TAS} angiogenesis, cellular hypotonic salinity response, ion transport, potassium ion transport, transmembrane transport basolateral plasma membrane, integral to membrane, membrane, plasma membrane potassium:chloride symporter activity Human SLC12A7 Reactome UniProtKB {GO:0005886=Reactome:REACT_19385, GO:0015379=GO_REF:0000002, GO:0005887=PMID:10347194, GO:0006810=PMID:10347194, GO:0055085=Reactome:REACT_19118, GO:0006813=GO_REF:0000037, GO:0006811=Reactome:REACT_19397, GO:0006884=GO_REF:0000019} Q9Y666 Solute carrier family 12 member 7 protein 20130301 {GO:0005886=TAS, GO:0015379=IEA, GO:0005887=TAS, GO:0006810=TAS, GO:0055085=TAS, GO:0006813=IEA, GO:0006811=TAS, GO:0006884=IEA} cell volume homeostasis, ion transport, potassium ion transport, transmembrane transport, transport integral to plasma membrane, plasma membrane potassium:chloride symporter activity Human SLC12A9 PINC UniProtKB {GO:0005886=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0015377=PMID:10871601, GO:0016021=GO_REF:0000037, GO:0055085=GO_REF:0000002} Q9BXP2 Solute carrier family 12 member 9 protein 20090803 {GO:0005886=IEA, GO:0016020=IEA, GO:0015377=TAS, GO:0016021=IEA, GO:0055085=IEA} transmembrane transport integral to membrane, membrane, plasma membrane cation:chloride symporter activity Human SLC14A2 Reactome UniProtKB {GO:0016324=GO_REF:0000039, GO:0005886=Reactome:REACT_20655, GO:0016020=PMID:8647271, GO:0015204=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0015840=PMID:8647271} Q15849 Urea transporter 2 protein 20130301 {GO:0016324=IEA, GO:0005886=TAS, GO:0016020=TAS, GO:0015204=IEA, GO:0016021=IEA, GO:0055085=TAS, GO:0015840=TAS} transmembrane transport, urea transport apical plasma membrane, integral to membrane, membrane, plasma membrane urea transmembrane transporter activity Human SLC15A1 InterPro UniProtKB {GO:0005215=GO_REF:0000002, GO:0005427=GO_REF:0000019, GO:0006857=GO_REF:0000002, GO:0005886=Reactome:REACT_19313, GO:0016020=GO_REF:0000002, GO:0005887=PMID:7896779, GO:0007586=PMID:7896779, GO:0006810=PMID:7896779, GO:0015031=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0015333=PMID:7896779, GO:0006811=Reactome:REACT_19397} Q9BZ22 Solute carrier family 15 member 1 protein 20130413 {GO:0005215=IEA, GO:0005427=IEA, GO:0006857=IEA, GO:0005886=TAS, GO:0016020=IEA, GO:0005887=TAS, GO:0007586=TAS, GO:0006810=TAS, GO:0015031=IEA, GO:0055085=TAS, GO:0015333=TAS, GO:0006811=TAS} digestion, ion transport, oligopeptide transport, protein transport, transmembrane transport, transport integral to plasma membrane, membrane, plasma membrane peptide:hydrogen symporter activity, proton-dependent oligopeptide secondary active transmembrane transporter activity, transporter activity Human InterPro:IPR000109|InterPro:IPR018456 SLC15A2 Reactome UniProtKB {GO:0005515=PMID:16738539, GO:0005886=Reactome:REACT_19313, GO:0005887=GO_REF:0000019, GO:0006810=PMID:7756356, GO:0015893=PMID:16738539, GO:0015031=GO_REF:0000037, GO:0042895=GO_REF:0000019, GO:0055085=Reactome:REACT_19118, GO:0015333=PMID:7756356, GO:0042936=GO_REF:0000019, GO:0015334=GO_REF:0000019, GO:0006811=Reactome:REACT_19397} Q16348 Solute carrier family 15 member 2 protein 20130301 {GO:0005515=IPI, GO:0005886=TAS, GO:0005887=IEA, GO:0006810=TAS, GO:0015893=NAS, GO:0015031=IEA, GO:0042895=IEA, GO:0055085=TAS, GO:0015333=TAS, GO:0042936=IEA, GO:0015334=IEA, GO:0006811=TAS} drug transport, ion transport, protein transport, transmembrane transport, transport integral to plasma membrane, plasma membrane antibiotic transporter activity, dipeptide transporter activity, high affinity oligopeptide transporter activity, peptide:hydrogen symporter activity, protein binding Human SLC15A3 Reactome UniProtKB {GO:0005215=GO_REF:0000002, GO:0015833=GO_REF:0000037, GO:0016020=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0005765=Reactome:REACT_19377, GO:0055085=Reactome:REACT_19118, GO:0006811=Reactome:REACT_19397, GO:0015293=GO_REF:0000037} Q8IY34 Solute carrier family 15 member 3 protein 20130301 {GO:0005215=IEA, GO:0015833=IEA, GO:0016020=IEA, GO:0016021=IEA, GO:0015031=IEA, GO:0005765=TAS, GO:0055085=TAS, GO:0006811=TAS, GO:0015293=IEA} ion transport, peptide transport, protein transport, transmembrane transport integral to membrane, lysosomal membrane, membrane symporter activity, transporter activity Human SLC15A4 Reactome UniProtKB {GO:0005215=GO_REF:0000002, GO:0005290=GO_REF:0000019, GO:0006857=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005765=Reactome:REACT_19377, GO:0015031=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0006811=Reactome:REACT_19397, GO:0015293=GO_REF:0000037} Q8N697 Solute carrier family 15 member 4 protein 20130301 {GO:0005215=IEA, GO:0005290=IEA, GO:0006857=IEA, GO:0016020=IEA, GO:0016021=IEA, GO:0005765=TAS, GO:0015031=IEA, GO:0055085=TAS, GO:0006811=TAS, GO:0015293=IEA} ion transport, oligopeptide transport, protein transport, transmembrane transport integral to membrane, lysosomal membrane, membrane L-histidine transmembrane transporter activity, symporter activity, transporter activity Human SLC16A1 HPA UniProtKB {GO:0005886=GO_REF:0000052, GO:0008028=PMID:8124722, GO:0044281=Reactome:REACT_111217, GO:0050900=Reactome:REACT_12051, GO:0055085=GO_REF:0000002, GO:0005739=GO_REF:0000019, GO:0015130=PMID:1429658, GO:0015718=PMID:8124722, GO:0015728=PMID:1429658, GO:0016020=PMID:8124722, GO:0006090=Reactome:REACT_2071, GO:0007596=Reactome:REACT_604, GO:0015355=GO_REF:0000002, GO:0016021=GO_REF:0000002, GO:0015293=GO_REF:0000037} Q5T8R5 Monocarboxylate transporter 1 protein 20080205 {GO:0005886=IDA, GO:0008028=TAS, GO:0044281=TAS, GO:0050900=TAS, GO:0055085=IEA, GO:0005739=IEA, GO:0015130=TAS, GO:0015718=TAS, GO:0015728=TAS, GO:0016020=TAS, GO:0006090=TAS, GO:0007596=TAS, GO:0015355=IEA, GO:0016021=IEA, GO:0015293=IEA} blood coagulation, leukocyte migration, mevalonate transport, monocarboxylic acid transport, pyruvate metabolic process, small molecule metabolic process, transmembrane transport integral to membrane, membrane, mitochondrion, plasma membrane mevalonate transmembrane transporter activity, monocarboxylic acid transmembrane transporter activity, secondary active monocarboxylate transmembrane transporter activity, symporter activity Human SLC16A10 InterPro UniProtKB {GO:0016323=PMID:15918515, GO:0005886=Reactome:REACT_13410, GO:0015801=PMID:15918515, GO:0006865=Reactome:REACT_13796, GO:0016021=GO_REF:0000002, GO:0055085=GO_REF:0000002, GO:0006811=Reactome:REACT_19397} Q9P1I2 PRO0813 protein 20130413 {GO:0016323=TAS, GO:0005886=TAS, GO:0015801=TAS, GO:0006865=TAS, GO:0016021=IEA, GO:0055085=IEA, GO:0006811=TAS} amino acid transport, aromatic amino acid transport, ion transport, transmembrane transport basolateral plasma membrane, integral to membrane, plasma membrane Human InterPro:IPR011701 SLC16A13 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0015293=GO_REF:0000037} Q7RTY0 Monocarboxylate transporter 13 protein 20130413 {GO:0005886=IEA, GO:0016021=IEA, GO:0015293=IEA} integral to membrane, plasma membrane symporter activity Human UniProtKB-SubCell:SL-0039 SLC16A2 PINC UniProtKB {GO:0015718=PMID:9425115, GO:0005215=PMID:7981683, GO:0016020=PMID:9425115, GO:0005887=PMID:9425115, GO:0008028=PMID:9425115, GO:0006810=PMID:7981683, GO:0016021=GO_REF:0000002, GO:0055085=GO_REF:0000002, GO:0015293=GO_REF:0000037} P36021 Monocarboxylate transporter 8 protein 20030904 {GO:0015718=TAS, GO:0005215=TAS, GO:0016020=TAS, GO:0005887=TAS, GO:0008028=TAS, GO:0006810=TAS, GO:0016021=IEA, GO:0055085=IEA, GO:0015293=IEA} monocarboxylic acid transport, transmembrane transport, transport integral to membrane, integral to plasma membrane, membrane monocarboxylic acid transmembrane transporter activity, symporter activity, transporter activity Human SLC16A3 HPA UniProtKB {GO:0031965=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0008028=PMID:9425115, GO:0044281=Reactome:REACT_111217, GO:0015629=GO_REF:0000052, GO:0050900=Reactome:REACT_12051, GO:0055085=Reactome:REACT_19118, GO:0015718=PMID:9425115, GO:0016020=PMID:9425115, GO:0005887=PMID:9425115, GO:0006090=Reactome:REACT_2071, GO:0007596=Reactome:REACT_604, GO:0015355=GO_REF:0000002, GO:0016021=GO_REF:0000002, GO:0015293=GO_REF:0000037} O15427 Monocarboxylate transporter 4 protein 20101115 {GO:0031965=IDA, GO:0005886=IDA, GO:0008028=TAS, GO:0044281=TAS, GO:0015629=IDA, GO:0050900=TAS, GO:0055085=TAS, GO:0015718=TAS, GO:0016020=TAS, GO:0005887=TAS, GO:0006090=TAS, GO:0007596=TAS, GO:0015355=IEA, GO:0016021=IEA, GO:0015293=IEA} blood coagulation, leukocyte migration, monocarboxylic acid transport, pyruvate metabolic process, small molecule metabolic process, transmembrane transport actin cytoskeleton, integral to membrane, integral to plasma membrane, membrane, nuclear membrane, plasma membrane monocarboxylic acid transmembrane transporter activity, secondary active monocarboxylate transmembrane transporter activity, symporter activity Human SLC16A4 PINC UniProtKB {GO:0015718=PMID:9425115, GO:0016020=PMID:9425115, GO:0005887=PMID:9425115, GO:0008028=PMID:9425115, GO:0016021=GO_REF:0000002, GO:0055085=GO_REF:0000002, GO:0015293=GO_REF:0000037} O15374 Monocarboxylate transporter 5 protein 20030904 {GO:0015718=TAS, GO:0016020=TAS, GO:0005887=TAS, GO:0008028=TAS, GO:0016021=IEA, GO:0055085=IEA, GO:0015293=IEA} monocarboxylic acid transport, transmembrane transport integral to membrane, integral to plasma membrane, membrane monocarboxylic acid transmembrane transporter activity, symporter activity Human SLC16A5 PINC UniProtKB {GO:0015718=PMID:9425115, GO:0016020=PMID:9425115, GO:0005887=PMID:9425115, GO:0008028=PMID:9425115, GO:0015355=GO_REF:0000002, GO:0016021=GO_REF:0000002, GO:0055085=GO_REF:0000002, GO:0015293=GO_REF:0000037} O15375 Monocarboxylate transporter 6 protein 20030904 {GO:0015718=TAS, GO:0016020=TAS, GO:0005887=TAS, GO:0008028=TAS, GO:0015355=IEA, GO:0016021=IEA, GO:0055085=IEA, GO:0015293=IEA} monocarboxylic acid transport, transmembrane transport integral to membrane, integral to plasma membrane, membrane monocarboxylic acid transmembrane transporter activity, secondary active monocarboxylate transmembrane transporter activity, symporter activity Human SLC16A6 PINC UniProtKB {GO:0015718=PMID:9425115, GO:0016020=PMID:9425115, GO:0005887=PMID:9425115, GO:0008028=PMID:9425115, GO:0015293=GO_REF:0000037} O15403 Monocarboxylate transporter 7 protein 20030904 {GO:0015718=TAS, GO:0016020=TAS, GO:0005887=TAS, GO:0008028=TAS, GO:0015293=IEA} monocarboxylic acid transport integral to plasma membrane, membrane monocarboxylic acid transmembrane transporter activity, symporter activity Human SLC16A7 Reactome UniProtKB {GO:0005886=Reactome:REACT_20553, GO:0016020=PMID:9786900, GO:0005887=PMID:9786900, GO:0005477=PMID:9786900, GO:0015355=GO_REF:0000002, GO:0016021=GO_REF:0000002, GO:0006848=PMID:9786900, GO:0055085=Reactome:REACT_19118, GO:0015293=GO_REF:0000037} O60669 Monocarboxylate transporter 2 protein 20130301 {GO:0005886=TAS, GO:0016020=TAS, GO:0005887=TAS, GO:0005477=TAS, GO:0015355=IEA, GO:0016021=IEA, GO:0006848=TAS, GO:0055085=TAS, GO:0015293=IEA} pyruvate transport, transmembrane transport integral to membrane, integral to plasma membrane, membrane, plasma membrane pyruvate secondary active transmembrane transporter activity, secondary active monocarboxylate transmembrane transporter activity, symporter activity Human SLC16A8 GOC UniProtKB {GO:0005886=Reactome:REACT_20553, GO:0015129=PMID:10493836, GO:0044281=Reactome:REACT_111217, GO:0050900=Reactome:REACT_12051, GO:0055085=Reactome:REACT_19118, GO:0015727=PMID:10493836, GO:0035873=PMID:10493836, GO:0016020=PMID:10493836, GO:0005887=PMID:10493836, GO:0006090=Reactome:REACT_2071, GO:0007596=Reactome:REACT_604, GO:0015355=GO_REF:0000002, GO:0015293=GO_REF:0000037} O95907 Monocarboxylate transporter 3 protein 20130413 {GO:0005886=TAS, GO:0015129=TAS, GO:0044281=TAS, GO:0050900=TAS, GO:0055085=TAS, GO:0015727=TAS, GO:0035873=TAS, GO:0016020=TAS, GO:0005887=TAS, GO:0006090=TAS, GO:0007596=TAS, GO:0015355=IEA, GO:0015293=IEA} blood coagulation, lactate transmembrane transport, lactate transport, leukocyte migration, pyruvate metabolic process, small molecule metabolic process, transmembrane transport integral to plasma membrane, membrane, plasma membrane lactate transmembrane transporter activity, secondary active monocarboxylate transmembrane transporter activity, symporter activity Human SLC16A9 BHF-UCL UniProtKB {GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0046415=PMID:19503597, GO:0015293=GO_REF:0000037} Q7RTY1 Monocarboxylate transporter 9 protein 20100929 {GO:0005886=IEA, GO:0016021=IEA, GO:0046415=IMP, GO:0015293=IEA} urate metabolic process integral to membrane, plasma membrane symporter activity Human SLC17A1 GOC UniProtKB {GO:0044341=PMID:8867793, GO:0015321=PMID:8867793, GO:0005886=Reactome:REACT_19157, GO:0016020=PMID:8288239, GO:0005887=PMID:8288239, GO:0006817=PMID:8867793, GO:0016021=GO_REF:0000002, GO:0046415=PMID:19503597, GO:0006814=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0006811=Reactome:REACT_19397, GO:0015293=GO_REF:0000037} Q14916 Sodium-dependent phosphate transport protein 1 protein 20130413 {GO:0044341=TAS, GO:0015321=TAS, GO:0005886=TAS, GO:0016020=TAS, GO:0005887=TAS, GO:0006817=TAS, GO:0016021=IEA, GO:0046415=IMP, GO:0006814=IEA, GO:0055085=TAS, GO:0006811=TAS, GO:0015293=IEA} ion transport, phosphate ion transport, sodium ion transport, sodium-dependent phosphate transport, transmembrane transport, urate metabolic process integral to membrane, integral to plasma membrane, membrane, plasma membrane sodium-dependent phosphate transmembrane transporter activity, symporter activity Human SLC17A2 PINC UniProtKB {GO:0005436=PMID:9149941, GO:0016020=PMID:9149941, GO:0005887=PMID:9149941, GO:0006796=PMID:9149941, GO:0016021=GO_REF:0000002, GO:0006814=PMID:9149941, GO:0055085=GO_REF:0000002} O00624 Sodium-dependent phosphate transport protein 3 protein 20030904 {GO:0005436=TAS, GO:0016020=TAS, GO:0005887=TAS, GO:0006796=TAS, GO:0016021=IEA, GO:0006814=TAS, GO:0055085=IEA} phosphate-containing compound metabolic process, sodium ion transport, transmembrane transport integral to membrane, integral to plasma membrane, membrane sodium:phosphate symporter activity Human SLC17A5 Reactome UniProtKB {GO:0006820=PMID:10581036, GO:0030054=GO_REF:0000037, GO:0006865=GO_REF:0000037, GO:0005765=Reactome:REACT_19297, GO:0055085=Reactome:REACT_19118, GO:0015739=PMID:10581036, GO:0016020=PMID:10581036, GO:0005887=PMID:10581036, GO:0015136=PMID:10581036, GO:0030672=GO_REF:0000039, GO:0005351=PMID:10581036, GO:0016021=GO_REF:0000002, GO:0006811=Reactome:REACT_19397} Q9NRA2 Sialin protein 20130301 {GO:0006820=TAS, GO:0030054=IEA, GO:0006865=IEA, GO:0005765=TAS, GO:0055085=TAS, GO:0015739=IDA, GO:0016020=TAS, GO:0005887=TAS, GO:0015136=IDA, GO:0030672=IEA, GO:0005351=TAS, GO:0016021=IEA, GO:0006811=TAS} amino acid transport, anion transport, ion transport, sialic acid transport, transmembrane transport cell junction, integral to membrane, integral to plasma membrane, lysosomal membrane, membrane, synaptic vesicle membrane sialic acid transmembrane transporter activity, sugar:hydrogen symporter activity Human SLC17A7 Reactome UniProtKB {GO:0043005=GO_REF:0000039, GO:0048786=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_12411, GO:0007616=GO_REF:0000019, GO:0051938=GO_REF:0000019, GO:0005313=Reactome:REACT_12503, GO:0035249=GO_REF:0000019, GO:0060079=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0015319=PMID:10820226, GO:0060076=GO_REF:0000019, GO:0055085=Reactome:REACT_19118, GO:0014047=Reactome:REACT_12591, GO:0060203=Reactome:REACT_12617, GO:0007269=Reactome:REACT_13723, GO:0015321=GO_REF:0000019, GO:0006817=PMID:8632143, GO:0030672=Reactome:REACT_19233, GO:0042137=GO_REF:0000019, GO:0005315=GO_REF:0000019, GO:0016021=PMID:10820226, GO:0006811=Reactome:REACT_19397} Q9P2U7 Vesicular glutamate transporter 1 protein 20130213 {GO:0043005=IEA, GO:0048786=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0007616=IEA, GO:0051938=IEA, GO:0005313=TAS, GO:0035249=IEA, GO:0060079=IEA, GO:0007268=TAS, GO:0015319=IDA, GO:0060076=IEA, GO:0055085=TAS, GO:0014047=TAS, GO:0060203=TAS, GO:0007269=TAS, GO:0015321=IEA, GO:0006817=TAS, GO:0030672=TAS, GO:0042137=IEA, GO:0005315=IEA, GO:0016021=IDA, GO:0006811=TAS} L-glutamate import, glutamate secretion, ion transport, long-term memory, neurotransmitter secretion, phosphate ion transport, regulation of excitatory postsynaptic membrane potential, sequestering of neurotransmitter, synaptic transmission, synaptic transmission, glutamatergic, transmembrane transport cell junction, clathrin-sculpted glutamate transport vesicle membrane, excitatory synapse, integral to membrane, neuron projection, plasma membrane, presynaptic active zone, synaptic vesicle membrane L-glutamate transmembrane transporter activity, inorganic phosphate transmembrane transporter activity, sodium-dependent phosphate transmembrane transporter activity, sodium:inorganic phosphate symporter activity Human SLC17A9 UniProtKB UniProtKB {GO:0005215=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0006887=GO_REF:0000037, GO:0055085=GO_REF:0000002} Q9BYT1 Solute carrier family 17 member 9 protein 20130413 {GO:0005215=IEA, GO:0016021=IEA, GO:0006887=IEA, GO:0055085=IEA} exocytosis, transmembrane transport integral to membrane transporter activity Human UniProtKB-KW:KW-0812 SLC18A1 InterPro UniProtKB {GO:0070083=Reactome:REACT_20519, GO:0016020=GO_REF:0000029, GO:0005789=GO_REF:0000039, GO:0006836=GO_REF:0000037, GO:0008504=PMID:8643547, GO:0016021=GO_REF:0000002, GO:0015844=PMID:8643547, GO:0055085=Reactome:REACT_19118, GO:0015238=GO_REF:0000002} Q96GL6 SLC18A1 protein protein 20130413 {GO:0070083=TAS, GO:0016020=NAS, GO:0005789=IEA, GO:0006836=IEA, GO:0008504=TAS, GO:0016021=IEA, GO:0015844=TAS, GO:0055085=TAS, GO:0015238=IEA} monoamine transport, neurotransmitter transport, transmembrane transport clathrin-sculpted monoamine transport vesicle membrane, endoplasmic reticulum membrane, integral to membrane, membrane drug transmembrane transporter activity, monoamine transmembrane transporter activity Human InterPro:IPR004734|InterPro:IPR011701 SLC18A2 Reactome UniProtKB {GO:0070083=Reactome:REACT_20519, GO:0005886=Reactome:REACT_15533, GO:0032456=GO_REF:0000019, GO:0016265=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0031045=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0042220=GO_REF:0000019, GO:0010043=GO_REF:0000019, GO:0007269=Reactome:REACT_13723, GO:0042594=GO_REF:0000019, GO:0008144=GO_REF:0000019, GO:0031072=GO_REF:0000019, GO:0043195=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0030672=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0051589=GO_REF:0000019, GO:0051412=GO_REF:0000019, GO:0015222=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0009635=GO_REF:0000019, GO:0042593=GO_REF:0000019, GO:0055085=Reactome:REACT_19118, GO:0035690=GO_REF:0000019, GO:0001975=GO_REF:0000019, GO:0016020=PMID:8095030, GO:0005887=PMID:8095030, GO:0008504=PMID:8095030, GO:0015844=PMID:8095030, GO:0019899=GO_REF:0000019, GO:0071242=GO_REF:0000019, GO:0030073=GO_REF:0000019} Q05940 Synaptic vesicular amine transporter protein 20130213 {GO:0070083=TAS, GO:0005886=TAS, GO:0032456=IEA, GO:0016265=IEA, GO:0007268=TAS, GO:0031045=IEA, GO:0009791=IEA, GO:0042220=IEA, GO:0010043=IEA, GO:0007269=TAS, GO:0042594=IEA, GO:0008144=IEA, GO:0031072=IEA, GO:0043195=IEA, GO:0043025=IEA, GO:0030672=IEA, GO:0007626=IEA, GO:0051589=IEA, GO:0051412=IEA, GO:0015222=IEA, GO:0007568=IEA, GO:0009635=IEA, GO:0042593=IEA, GO:0055085=TAS, GO:0035690=IEA, GO:0001975=IEA, GO:0016020=TAS, GO:0005887=TAS, GO:0008504=TAS, GO:0015844=TAS, GO:0019899=IEA, GO:0071242=IEA, GO:0030073=IEA} aging, cellular response to ammonium ion, cellular response to drug, death, endocytic recycling, glucose homeostasis, insulin secretion, locomotory behavior, monoamine transport, negative regulation of neurotransmitter transport, neurotransmitter secretion, post-embryonic development, response to amphetamine, response to cocaine, response to corticosterone stimulus, response to herbicide, response to starvation, response to zinc ion, synaptic transmission, transmembrane transport clathrin-sculpted monoamine transport vesicle membrane, dense core granule, integral to plasma membrane, membrane, neuronal cell body, plasma membrane, synaptic vesicle membrane, terminal bouton drug binding, enzyme binding, heat shock protein binding, monoamine transmembrane transporter activity, serotonin transmembrane transporter activity Human SLC18A3 Reactome UniProtKB {GO:0060201=Reactome:REACT_15483, GO:0015870=PMID:8071310, GO:0005886=Reactome:REACT_15404, GO:0016020=PMID:8071310, GO:0005887=PMID:8071310, GO:0005277=PMID:8071310, GO:0007268=Reactome:REACT_13685, GO:0007269=Reactome:REACT_13723} Q16572 Vesicular acetylcholine transporter protein 20130213 {GO:0060201=TAS, GO:0015870=TAS, GO:0005886=TAS, GO:0016020=TAS, GO:0005887=TAS, GO:0005277=TAS, GO:0007268=TAS, GO:0007269=TAS} acetylcholine transport, neurotransmitter secretion, synaptic transmission clathrin-sculpted acetylcholine transport vesicle membrane, integral to plasma membrane, membrane, plasma membrane acetylcholine transmembrane transporter activity Human SLC19A1 GOC UniProtKB {GO:0005886=Reactome:REACT_11162, GO:0015884=PMID:7826387, GO:0008518=GO_REF:0000002, GO:0006767=Reactome:REACT_11238, GO:0008517=PMID:7826387, GO:0044281=Reactome:REACT_111217, GO:0005542=GO_REF:0000037, GO:0016020=PMID:8276792, GO:0005887=PMID:7826387, GO:0006766=Reactome:REACT_11193, GO:0046655=Reactome:REACT_11167, GO:0015350=PMID:8276792, GO:0051958=PMID:8276792} P41440 Folate transporter 1 protein 20130413 {GO:0005886=TAS, GO:0015884=TAS, GO:0008518=IEA, GO:0006767=TAS, GO:0008517=TAS, GO:0044281=TAS, GO:0005542=IEA, GO:0016020=TAS, GO:0005887=TAS, GO:0006766=TAS, GO:0046655=TAS, GO:0015350=TAS, GO:0051958=TAS} folic acid metabolic process, folic acid transport, methotrexate transport, small molecule metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process integral to plasma membrane, membrane, plasma membrane folic acid binding, folic acid transporter activity, methotrexate transporter activity, reduced folate carrier activity Human SLC19A2 InterPro UniProtKB {GO:0015403=GO_REF:0000024, GO:0015234=PMID:10542220, GO:0015888=PMID:10542220, GO:0005886=Reactome:REACT_11081, GO:0015884=PMID:10542220, GO:0008518=GO_REF:0000002, GO:0006767=Reactome:REACT_11238, GO:0071934=GO_REF:0000019, GO:0008517=PMID:10542220, GO:0044281=Reactome:REACT_111217, GO:0042723=Reactome:REACT_11117, GO:0005542=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0006766=Reactome:REACT_11193, GO:0016021=PMID:10542220} Q5TIE1 Thiamine transporter 1 protein 20130413 {GO:0015403=ISS, GO:0015234=TAS, GO:0015888=NAS, GO:0005886=TAS, GO:0015884=NAS, GO:0008518=IEA, GO:0006767=TAS, GO:0071934=IEA, GO:0008517=NAS, GO:0044281=TAS, GO:0042723=TAS, GO:0005542=IEA, GO:0016020=IEA, GO:0006766=TAS, GO:0016021=NAS} folic acid transport, small molecule metabolic process, thiamine transmembrane transport, thiamine transport, thiamine-containing compound metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process integral to membrane, membrane, plasma membrane folic acid binding, folic acid transporter activity, reduced folate carrier activity, thiamine transmembrane transporter activity, thiamine uptake transmembrane transporter activity Human InterPro:IPR002666 SLC19A3 BHF-UCL UniProtKB {GO:0015403=GO_REF:0000024, GO:0005542=GO_REF:0000002, GO:0005886=Reactome:REACT_11081, GO:0016020=GO_REF:0000002, GO:0006766=Reactome:REACT_11193, GO:0006810=GO_REF:0000029, GO:0008518=GO_REF:0000002, GO:0006767=Reactome:REACT_11238, GO:0044281=Reactome:REACT_111217, GO:0016021=PMID:11136550, GO:0042723=Reactome:REACT_11117} Q9BZV2 Thiamine transporter 2 protein 20110119 {GO:0015403=ISS, GO:0005542=IEA, GO:0005886=TAS, GO:0016020=IEA, GO:0006766=TAS, GO:0006810=NAS, GO:0008518=IEA, GO:0006767=TAS, GO:0044281=TAS, GO:0016021=NAS, GO:0042723=TAS} small molecule metabolic process, thiamine-containing compound metabolic process, transport, vitamin metabolic process, water-soluble vitamin metabolic process integral to membrane, membrane, plasma membrane folic acid binding, reduced folate carrier activity, thiamine uptake transmembrane transporter activity Human UniProtKB:Q99PL8 SLC1A1 Reactome UniProtKB {GO:0015501=GO_REF:0000019, GO:0005886=Reactome:REACT_19362, GO:0051938=PMID:7521911, GO:0070779=PMID:7521911, GO:0005313=PMID:7521911, GO:0007268=PMID:7521911, GO:0055085=Reactome:REACT_15518, GO:0016020=PMID:7521911, GO:0005887=PMID:7521911, GO:0051260=GO_REF:0000019, GO:0017153=GO_REF:0000002, GO:0016595=GO_REF:0000019, GO:0006811=Reactome:REACT_19397} P43005 Excitatory amino acid transporter 3 protein 20130301 {GO:0015501=IEA, GO:0005886=TAS, GO:0051938=IDA, GO:0070779=IDA, GO:0005313=TAS, GO:0007268=TAS, GO:0055085=TAS, GO:0016020=TAS, GO:0005887=TAS, GO:0051260=IEA, GO:0017153=IEA, GO:0016595=IEA, GO:0006811=TAS} D-aspartate import, L-glutamate import, ion transport, protein homooligomerization, synaptic transmission, transmembrane transport integral to plasma membrane, membrane, plasma membrane L-glutamate transmembrane transporter activity, glutamate binding, glutamate:sodium symporter activity, sodium:dicarboxylate symporter activity Human SLC1A2 Reactome UniProtKB {GO:0015501=GO_REF:0000019, GO:0005886=Reactome:REACT_19362, GO:0051938=PMID:7521911, GO:0007632=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0005313=PMID:7521911, GO:0070779=PMID:7521911, GO:0009611=GO_REF:0000019, GO:0007268=PMID:7521911, GO:0010259=GO_REF:0000019, GO:0055085=Reactome:REACT_19118, GO:0021537=GO_REF:0000019, GO:0016020=PMID:7521911, GO:0035264=GO_REF:0000019, GO:0046326=GO_REF:0000019, GO:0031668=GO_REF:0000019, GO:0030534=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0030673=GO_REF:0000019, GO:0017153=GO_REF:0000002, GO:0043200=GO_REF:0000019, GO:0006811=Reactome:REACT_19397} P43004 Excitatory amino acid transporter 2 protein 20130301 {GO:0015501=IEA, GO:0005886=TAS, GO:0051938=IDA, GO:0007632=IEA, GO:0042493=IEA, GO:0005313=TAS, GO:0070779=IDA, GO:0009611=IEA, GO:0007268=TAS, GO:0010259=IEA, GO:0055085=TAS, GO:0021537=IEA, GO:0016020=TAS, GO:0035264=IEA, GO:0046326=IEA, GO:0031668=IEA, GO:0030534=IEA, GO:0016021=IEA, GO:0030673=IEA, GO:0017153=IEA, GO:0043200=IEA, GO:0006811=TAS} D-aspartate import, L-glutamate import, adult behavior, cellular response to extracellular stimulus, ion transport, multicellular organism growth, multicellular organismal aging, positive regulation of glucose import, response to amino acid stimulus, response to drug, response to wounding, synaptic transmission, telencephalon development, transmembrane transport, visual behavior axolemma, integral to membrane, membrane, plasma membrane L-glutamate transmembrane transporter activity, glutamate:sodium symporter activity, sodium:dicarboxylate symporter activity Human SLC1A3 Reactome UniProtKB {GO:0005886=Reactome:REACT_19362, GO:0007605=GO_REF:0000019, GO:0005314=GO_REF:0000019, GO:0005313=PMID:7521911, GO:0070779=PMID:7521911, GO:0007268=PMID:7521911, GO:0042995=GO_REF:0000019, GO:0031223=GO_REF:0000019, GO:0048667=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0050885=GO_REF:0000019, GO:0009416=GO_REF:0000019, GO:0043205=GO_REF:0000019, GO:0017153=GO_REF:0000002, GO:0046677=GO_REF:0000019, GO:0006811=Reactome:REACT_19397, GO:0009986=GO_REF:0000019, GO:0006537=GO_REF:0000019, GO:0021545=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0051938=PMID:7521911, GO:0009611=GO_REF:0000019, GO:0055085=Reactome:REACT_19118, GO:0016020=PMID:7521911, GO:0050806=GO_REF:0000019, GO:0001504=PMID:8647279, GO:0016595=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0009449=GO_REF:0000019} P43003 Excitatory amino acid transporter 1 protein 20130301 {GO:0005886=TAS, GO:0007605=IEA, GO:0005314=IEA, GO:0005313=TAS, GO:0070779=IDA, GO:0007268=TAS, GO:0042995=IEA, GO:0031223=IEA, GO:0048667=IEA, GO:0043025=IEA, GO:0050885=IEA, GO:0009416=IEA, GO:0043205=IEA, GO:0017153=IEA, GO:0046677=IEA, GO:0006811=TAS, GO:0009986=IEA, GO:0006537=IEA, GO:0021545=IEA, GO:0042493=IEA, GO:0051938=IDA, GO:0009611=IEA, GO:0055085=TAS, GO:0016020=TAS, GO:0050806=IEA, GO:0001504=TAS, GO:0016595=IEA, GO:0016021=IEA, GO:0009449=IEA} D-aspartate import, L-glutamate import, auditory behavior, cell morphogenesis involved in neuron differentiation, cranial nerve development, gamma-aminobutyric acid biosynthetic process, glutamate biosynthetic process, ion transport, neuromuscular process controlling balance, neurotransmitter uptake, positive regulation of synaptic transmission, response to antibiotic, response to drug, response to light stimulus, response to wounding, sensory perception of sound, synaptic transmission, transmembrane transport cell projection, cell surface, fibril, integral to membrane, membrane, neuronal cell body, plasma membrane L-glutamate transmembrane transporter activity, glutamate binding, high-affinity glutamate transmembrane transporter activity, sodium:dicarboxylate symporter activity Human SLC1A4 GOC UniProtKB {GO:0005882=GO_REF:0000024, GO:0006821=PMID:8910405, GO:0005886=Reactome:REACT_13745, GO:0006865=Reactome:REACT_13796, GO:0005254=PMID:8910405, GO:0030425=GO_REF:0000019, GO:0034590=PMID:14502423, GO:0015193=PMID:14502423, GO:0015195=PMID:8340364, GO:0015194=PMID:8910405, GO:0034589=PMID:14502423, GO:0015811=PMID:8910405, GO:0043025=GO_REF:0000019, GO:0017153=GO_REF:0000002, GO:0006811=Reactome:REACT_19397, GO:0042470=GO_REF:0000039, GO:0035249=PMID:16897601, GO:0055085=Reactome:REACT_19118, GO:0015180=PMID:8910405, GO:0015184=PMID:8910405, GO:0050890=PMID:16897601, GO:0015826=PMID:8340364, GO:0005887=PMID:8910405, GO:0006868=PMID:21757002, GO:0015825=PMID:8910405, GO:0035524=PMID:14502423, GO:0015824=PMID:14502423, GO:0015186=PMID:21757002, GO:0016021=PMID:8101838, GO:0015808=PMID:8910405} P43007 Neutral amino acid transporter A protein 20130413 {GO:0005882=ISS, GO:0006821=IDA, GO:0005886=TAS, GO:0006865=TAS, GO:0005254=IDA, GO:0030425=IEA, GO:0034590=IDA, GO:0015193=IDA, GO:0015195=IDA, GO:0015194=IDA, GO:0034589=IDA, GO:0015811=IDA, GO:0043025=IEA, GO:0017153=IEA, GO:0006811=TAS, GO:0042470=IEA, GO:0035249=NAS, GO:0055085=TAS, GO:0015180=IDA, GO:0015184=IDA, GO:0050890=IMP, GO:0015826=IDA, GO:0005887=IC, GO:0006868=TAS, GO:0015825=IDA, GO:0035524=IDA, GO:0015824=IDA, GO:0015186=TAS, GO:0016021=NAS, GO:0015808=IDA} L-alanine transport, L-cystine transport, L-serine transport, amino acid transport, chloride transport, cognition, glutamine transport, hydroxyproline transport, ion transport, proline transmembrane transport, proline transport, synaptic transmission, glutamatergic, threonine transport, transmembrane transport dendrite, integral to membrane, integral to plasma membrane, intermediate filament, melanosome, neuronal cell body, plasma membrane L-alanine transmembrane transporter activity, L-cystine transmembrane transporter activity, L-glutamine transmembrane transporter activity, L-hydroxyproline transmembrane transporter activity, L-proline transmembrane transporter activity, L-serine transmembrane transporter activity, L-threonine transmembrane transporter activity, chloride channel activity, sodium:dicarboxylate symporter activity Human SLC1A5 HPA UniProtKB {GO:0042470=GO_REF:0000039, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0006865=Reactome:REACT_13796, GO:0055085=Reactome:REACT_19118, GO:0015804=PMID:10051606, GO:0016020=PMID:8702519, GO:0005887=PMID:8702519, GO:0006868=PMID:21757002, GO:0015175=PMID:10051606, GO:0004872=PMID:10051606, GO:0015186=PMID:21757002, GO:0017153=GO_REF:0000002, GO:0006811=Reactome:REACT_19397} Q15758 Neutral amino acid transporter B(0) protein 20101115 {GO:0042470=IEA, GO:0005794=IDA, GO:0005886=IDA, GO:0006865=TAS, GO:0055085=TAS, GO:0015804=TAS, GO:0016020=TAS, GO:0005887=TAS, GO:0006868=TAS, GO:0015175=TAS, GO:0004872=TAS, GO:0015186=TAS, GO:0017153=IEA, GO:0006811=TAS} amino acid transport, glutamine transport, ion transport, neutral amino acid transport, transmembrane transport Golgi apparatus, integral to plasma membrane, melanosome, membrane, plasma membrane L-glutamine transmembrane transporter activity, neutral amino acid transmembrane transporter activity, receptor activity, sodium:dicarboxylate symporter activity Human SLC1A6 ENSEMBL UniProtKB {GO:0005794=GO_REF:0000019, GO:0005886=Reactome:REACT_19362, GO:0005313=GO_REF:0000019, GO:0007268=PMID:7791878, GO:0055085=Reactome:REACT_19118, GO:0015813=PMID:7791878, GO:0016020=GO_REF:0000019, GO:0015810=PMID:7791878, GO:0005887=PMID:7791878, GO:0015183=PMID:7791878, GO:0042391=GO_REF:0000019, GO:0017153=GO_REF:0000002, GO:0006811=Reactome:REACT_19397} Q8N753 Excitatory amino acid transporter 4 protein 20130413 {GO:0005794=IEA, GO:0005886=TAS, GO:0005313=IEA, GO:0007268=TAS, GO:0055085=TAS, GO:0015813=TAS, GO:0016020=IEA, GO:0015810=TAS, GO:0005887=TAS, GO:0015183=TAS, GO:0042391=IEA, GO:0017153=IEA, GO:0006811=TAS} L-glutamate transport, aspartate transport, ion transport, regulation of membrane potential, synaptic transmission, transmembrane transport Golgi apparatus, integral to plasma membrane, membrane, plasma membrane L-aspartate transmembrane transporter activity, L-glutamate transmembrane transporter activity, sodium:dicarboxylate symporter activity Human Ensembl:ENSMUSP00000005490 SLC1A7 InterPro UniProtKB {GO:0015813=PMID:9108121, GO:0016020=GO_REF:0000002, GO:0005886=Reactome:REACT_19362, GO:0005313=PMID:9108121, GO:0006835=PMID:9108121, GO:0016021=GO_REF:0000029, GO:0017153=GO_REF:0000002, GO:0055085=Reactome:REACT_19118, GO:0006811=Reactome:REACT_19397} Q9BW45 Excitatory amino acid transporter 5 protein 20130413 {GO:0015813=TAS, GO:0016020=IEA, GO:0005886=TAS, GO:0005313=TAS, GO:0006835=TAS, GO:0016021=NAS, GO:0017153=IEA, GO:0055085=TAS, GO:0006811=TAS} L-glutamate transport, dicarboxylic acid transport, ion transport, transmembrane transport integral to membrane, membrane, plasma membrane L-glutamate transmembrane transporter activity, sodium:dicarboxylate symporter activity Human InterPro:IPR001991 SLC20A1 GOC UniProtKB {GO:0005886=Reactome:REACT_19410, GO:0006796=PMID:8041748, GO:0055085=Reactome:REACT_19118, GO:0007165=PMID:12761501, GO:0005436=PMID:8041748, GO:0016020=PMID:8041748, GO:0005887=PMID:8041748, GO:0006810=PMID:8041748, GO:0006817=GO_REF:0000002, GO:0005315=GO_REF:0000002, GO:0004872=PMID:8041748, GO:0005316=GO_REF:0000019, GO:0004871=PMID:12761501, GO:0043123=PMID:12761501, GO:0006811=Reactome:REACT_19397} Q8WUM9 Sodium-dependent phosphate transporter 1 protein 20130413 {GO:0005886=TAS, GO:0006796=TAS, GO:0055085=TAS, GO:0007165=IMP, GO:0005436=TAS, GO:0016020=TAS, GO:0005887=TAS, GO:0006810=TAS, GO:0006817=IEA, GO:0005315=IEA, GO:0004872=TAS, GO:0005316=IEA, GO:0004871=IMP, GO:0043123=IMP, GO:0006811=TAS} ion transport, phosphate ion transport, phosphate-containing compound metabolic process, positive regulation of I-kappaB kinase/NF-kappaB cascade, signal transduction, transmembrane transport, transport integral to plasma membrane, membrane, plasma membrane high affinity inorganic phosphate:sodium symporter activity, inorganic phosphate transmembrane transporter activity, receptor activity, signal transducer activity, sodium:phosphate symporter activity Human SLC20A2 Reactome UniProtKB {GO:0005436=PMID:8302848, GO:0005886=Reactome:REACT_19410, GO:0016020=PMID:8302848, GO:0005887=PMID:8302848, GO:0019048=GO_REF:0000037, GO:0006810=PMID:8302848, GO:0006817=GO_REF:0000002, GO:0004872=PMID:8302848, GO:0005315=GO_REF:0000002, GO:0055085=Reactome:REACT_19118, GO:0006811=Reactome:REACT_19397} Q08357 Sodium-dependent phosphate transporter 2 protein 20130301 {GO:0005436=TAS, GO:0005886=TAS, GO:0016020=TAS, GO:0005887=TAS, GO:0019048=IEA, GO:0006810=TAS, GO:0006817=IEA, GO:0004872=TAS, GO:0005315=IEA, GO:0055085=TAS, GO:0006811=TAS} ion transport, phosphate ion transport, transmembrane transport, transport, virus-host interaction integral to plasma membrane, membrane, plasma membrane inorganic phosphate transmembrane transporter activity, receptor activity, sodium:phosphate symporter activity Human SLC22A1 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0005886=Reactome:REACT_121207, GO:0015695=PMID:9187257, GO:0005329=GO_REF:0000019, GO:0015874=GO_REF:0000019, GO:0015872=GO_REF:0000019, GO:0005277=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0010248=GO_REF:0000019, GO:0055085=Reactome:REACT_19118, GO:0015101=PMID:9187257, GO:0042802=GO_REF:0000019, GO:0016323=GO_REF:0000039, GO:0016020=PMID:9187257, GO:0005887=PMID:9187257, GO:0006855=Reactome:REACT_120801, GO:0008513=GO_REF:0000019, GO:0005333=GO_REF:0000019, GO:0048241=GO_REF:0000019} O15245 Solute carrier family 22 member 1 protein 20130415 {GO:0005515=IPI, GO:0005886=TAS, GO:0015695=TAS, GO:0005329=IEA, GO:0015874=IEA, GO:0015872=IEA, GO:0005277=IEA, GO:0044281=TAS, GO:0010248=IEA, GO:0055085=TAS, GO:0015101=TAS, GO:0042802=IEA, GO:0016323=IEA, GO:0016020=TAS, GO:0005887=TAS, GO:0006855=TAS, GO:0008513=IEA, GO:0005333=IEA, GO:0048241=IEA} dopamine transport, drug transmembrane transport, epinephrine transport, establishment or maintenance of transmembrane electrochemical gradient, norepinephrine transport, organic cation transport, small molecule metabolic process, transmembrane transport basolateral plasma membrane, integral to plasma membrane, membrane, plasma membrane acetylcholine transmembrane transporter activity, dopamine transmembrane transporter activity, identical protein binding, norepinephrine transmembrane transporter activity, organic cation transmembrane transporter activity, protein binding, secondary active organic cation transmembrane transporter activity Human UniProtKB:Q96G23 SLC22A11 BHF-UCL UniProtKB {GO:0005515=PMID:16236806, GO:0005886=Reactome:REACT_22294, GO:0015347=PMID:10660625, GO:0022857=GO_REF:0000002, GO:0046415=PMID:19503597, GO:0055085=Reactome:REACT_19118, GO:0016324=PMID:15037815, GO:0005452=PMID:15037815, GO:0005887=PMID:10660625, GO:0015711=PMID:10660625, GO:0008514=PMID:15291761, GO:0016021=GO_REF:0000038, GO:0009897=PMID:15102942} Q9NSA0 Solute carrier family 22 member 11 protein 20100929 {GO:0005515=IPI, GO:0005886=TAS, GO:0015347=IDA, GO:0022857=IEA, GO:0046415=IMP, GO:0055085=TAS, GO:0016324=IDA, GO:0005452=IDA, GO:0005887=IDA, GO:0015711=IDA, GO:0008514=IDA, GO:0016021=IEA, GO:0009897=IDA} organic anion transport, transmembrane transport, urate metabolic process apical plasma membrane, external side of plasma membrane, integral to membrane, integral to plasma membrane, plasma membrane inorganic anion exchanger activity, organic anion transmembrane transporter activity, protein binding, sodium-independent organic anion transmembrane transporter activity, transmembrane transporter activity Human SLC22A12 BHF-UCL UniProtKB {GO:0015143=PMID:12024214, GO:0019725=PMID:15772301, GO:0016324=PMID:12024214, GO:0005886=Reactome:REACT_22238, GO:0042493=PMID:12024214, GO:0015747=PMID:12024214, GO:0031526=GO_REF:0000024, GO:0016021=PMID:12024214, GO:0046415=PMID:19503597, GO:0030165=PMID:15304510, GO:0055085=Reactome:REACT_19118} Q96S37 Solute carrier family 22 member 12 protein 20100929 {GO:0015143=IDA, GO:0019725=NAS, GO:0016324=IDA, GO:0005886=TAS, GO:0042493=IDA, GO:0015747=IDA, GO:0031526=ISS, GO:0016021=IDA, GO:0046415=IMP, GO:0030165=IPI, GO:0055085=TAS} cellular homeostasis, response to drug, transmembrane transport, urate metabolic process, urate transport apical plasma membrane, brush border membrane, integral to membrane, plasma membrane PDZ domain binding, urate transmembrane transporter activity Human SLC22A17 UniProtKB UniProtKB {GO:0005774=GO_REF:0000039, GO:0031301=PMID:17253959, GO:0005887=PMID:17253959, GO:0022857=GO_REF:0000002, GO:0015891=GO_REF:0000024, GO:0016021=GO_REF:0000038, GO:0004888=GO_REF:0000024, GO:0006811=GO_REF:0000037} Q8WUG5 Solute carrier family 22 member 17 protein 20100721 {GO:0005774=IEA, GO:0031301=IDA, GO:0005887=IDA, GO:0022857=IEA, GO:0015891=ISS, GO:0016021=IEA, GO:0004888=ISS, GO:0006811=IEA} ion transport, siderophore transport integral to membrane, integral to organelle membrane, integral to plasma membrane, vacuolar membrane transmembrane signaling receptor activity, transmembrane transporter activity Human SLC22A18 GOC UniProtKB {GO:0005215=GO_REF:0000002, GO:0007588=PMID:9744804, GO:0005886=Reactome:REACT_22432, GO:0015695=PMID:9744804, GO:0005635=PMID:16314844, GO:0055085=Reactome:REACT_19118, GO:0044444=PMID:16314844, GO:0006855=PMID:9744804, GO:0016021=PMID:9499412, GO:0015893=PMID:9744804, GO:0015238=PMID:9744804, GO:0031625=PMID:16314844, GO:0015293=GO_REF:0000037} Q96BI1 Solute carrier family 22 member 18 protein 20130413 {GO:0005215=IEA, GO:0007588=NAS, GO:0005886=TAS, GO:0015695=NAS, GO:0005635=IDA, GO:0055085=TAS, GO:0044444=IDA, GO:0006855=IDA, GO:0016021=NAS, GO:0015893=IDA, GO:0015238=IDA, GO:0031625=IPI, GO:0015293=IEA} drug transmembrane transport, drug transport, excretion, organic cation transport, transmembrane transport cytoplasmic part, integral to membrane, nuclear envelope, plasma membrane drug transmembrane transporter activity, symporter activity, transporter activity, ubiquitin protein ligase binding Human SLC22A2 HPA UniProtKB {GO:0007589=PMID:9260930, GO:0015220=GO_REF:0000019, GO:0015695=PMID:16024787, GO:0005886=GO_REF:0000052, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0051608=GO_REF:0000019, GO:0055085=Reactome:REACT_19118, GO:0015101=PMID:16024787, GO:0007269=Reactome:REACT_13723, GO:0016323=GO_REF:0000019, GO:0016020=PMID:9260930, GO:0005887=GO_REF:0000019, GO:0006855=Reactome:REACT_120801, GO:0008513=GO_REF:0000019, GO:0042136=Reactome:REACT_13583, GO:0005496=GO_REF:0000019} Q5T7Q5 Solute carrier family 22 member 2 protein 20081203 {GO:0007589=TAS, GO:0015220=IEA, GO:0015695=IDA, GO:0005886=IDA, GO:0007268=TAS, GO:0044281=TAS, GO:0051608=IEA, GO:0055085=TAS, GO:0015101=IDA, GO:0007269=TAS, GO:0016323=IEA, GO:0016020=TAS, GO:0005887=IEA, GO:0006855=TAS, GO:0008513=IEA, GO:0042136=TAS, GO:0005496=IEA} body fluid secretion, drug transmembrane transport, histamine transport, neurotransmitter biosynthetic process, neurotransmitter secretion, organic cation transport, small molecule metabolic process, synaptic transmission, transmembrane transport basolateral plasma membrane, integral to plasma membrane, membrane, plasma membrane choline transmembrane transporter activity, organic cation transmembrane transporter activity, secondary active organic cation transmembrane transporter activity, steroid binding Human SLC22A23 UniProtKB UniProtKB {GO:0022857=GO_REF:0000002, GO:0016021=GO_REF:0000038, GO:0006811=GO_REF:0000037} H7C4T9 Solute carrier family 22 member 23 protein 20130413 {GO:0022857=IEA, GO:0016021=IEA, GO:0006811=IEA} ion transport integral to membrane transmembrane transporter activity Human UniProtKB-KW:KW-0812 SLC22A24 UniProtKB UniProtKB {GO:0022857=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0055085=GO_REF:0000002, GO:0006811=GO_REF:0000037} Q8N4F4 Solute carrier family 22 member 24 protein 20130413 {GO:0022857=IEA, GO:0016021=IEA, GO:0055085=IEA, GO:0006811=IEA} ion transport, transmembrane transport integral to membrane transmembrane transporter activity Human UniProtKB-KW:KW-0812 SLC22A3 UniProtKB UniProtKB {GO:0005515=PMID:17474147, GO:0019534=GO_REF:0000019, GO:0005329=GO_REF:0000019, GO:0015695=PMID:16024787, GO:0005886=Reactome:REACT_121207, GO:0015075=GO_REF:0000002, GO:0015872=GO_REF:0000019, GO:0015697=PMID:10966924, GO:0032098=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0055085=Reactome:REACT_19118, GO:0015101=PMID:16024787, GO:0015651=PMID:10966924, GO:0051615=GO_REF:0000019, GO:0016020=PMID:9933568, GO:0005887=PMID:9933568, GO:0006855=Reactome:REACT_120801, GO:0016021=GO_REF:0000038} Q96KH7 Solute carrier family 22 member 3 protein 20130413 {GO:0005515=IPI, GO:0019534=IEA, GO:0005329=IEA, GO:0015695=IDA, GO:0005886=TAS, GO:0015075=IEA, GO:0015872=IEA, GO:0015697=IDA, GO:0032098=IEA, GO:0044281=TAS, GO:0055085=TAS, GO:0015101=IDA, GO:0015651=IDA, GO:0051615=IEA, GO:0016020=TAS, GO:0005887=TAS, GO:0006855=TAS, GO:0016021=IEA} dopamine transport, drug transmembrane transport, histamine uptake, organic cation transport, quaternary ammonium group transport, regulation of appetite, small molecule metabolic process, transmembrane transport integral to membrane, integral to plasma membrane, membrane, plasma membrane dopamine transmembrane transporter activity, ion transmembrane transporter activity, organic cation transmembrane transporter activity, protein binding, quaternary ammonium group transmembrane transporter activity, toxin transporter activity Human UniProtKB-KW:KW-0812 SLC22A4 BHF-UCL UniProtKB {GO:0005515=PMID:15523054, GO:0007589=PMID:9426230, GO:0005886=PMID:9426230, GO:0015695=PMID:9426230, GO:0015491=PMID:9426230, GO:0015697=PMID:9426230, GO:0030165=PMID:15523054, GO:0015651=PMID:9426230, GO:0055085=Reactome:REACT_19118, GO:0005524=GO_REF:0000037, GO:0005739=PMID:16729965, GO:0016324=PMID:18641280, GO:0000166=PMID:9426230, GO:0005887=PMID:9426230, GO:0006641=GO_REF:0000019, GO:0008513=PMID:9426230, GO:0006814=GO_REF:0000037, GO:0015879=PMID:16729965, GO:0009437=GO_REF:0000019, GO:0015226=PMID:16729965, GO:0015293=GO_REF:0000037} Q9H015 Solute carrier family 22 member 4 protein 20090608 {GO:0005515=IPI, GO:0007589=TAS, GO:0005886=IC, GO:0015695=TAS, GO:0015491=IDA, GO:0015697=IDA, GO:0030165=IPI, GO:0015651=IDA, GO:0055085=TAS, GO:0005524=IEA, GO:0005739=IDA, GO:0016324=IDA, GO:0000166=TAS, GO:0005887=TAS, GO:0006641=IEA, GO:0008513=TAS, GO:0006814=IEA, GO:0015879=IDA, GO:0009437=IEA, GO:0015226=IDA, GO:0015293=IEA} body fluid secretion, carnitine metabolic process, carnitine transport, organic cation transport, quaternary ammonium group transport, sodium ion transport, transmembrane transport, triglyceride metabolic process apical plasma membrane, integral to plasma membrane, mitochondrion, plasma membrane ATP binding, PDZ domain binding, carnitine transmembrane transporter activity, cation:cation antiporter activity, nucleotide binding, protein binding, quaternary ammonium group transmembrane transporter activity, secondary active organic cation transmembrane transporter activity, symporter activity Human UniProtKB:O14745 SLC22A5 GOC UniProtKB {GO:0005515=PMID:15523054, GO:0060731=PMID:18005709, GO:0005886=PMID:9618255, GO:0052106=PMID:18005709, GO:0015697=PMID:9618255, GO:0022857=GO_REF:0000002, GO:0070715=PMID:15238359, GO:0031526=PMID:15238359, GO:0030165=PMID:15523054, GO:0005524=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0015651=PMID:9618255, GO:0016323=GO_REF:0000019, GO:0016324=PMID:17274673, GO:0006855=PMID:15238359, GO:0016021=GO_REF:0000037, GO:0015893=PMID:15238359, GO:0015879=PMID:9916797, GO:0006814=GO_REF:0000037, GO:0042895=GO_REF:0000019, GO:0015238=PMID:15238359, GO:0015226=PMID:9916797, GO:0015293=GO_REF:0000037} O76082 Solute carrier family 22 member 5 protein 20130413 {GO:0005515=IPI, GO:0060731=IMP, GO:0005886=IC, GO:0052106=IMP, GO:0015697=IDA, GO:0022857=IEA, GO:0070715=IDA, GO:0031526=IDA, GO:0030165=IPI, GO:0005524=IEA, GO:0055085=TAS, GO:0015651=IDA, GO:0016323=IEA, GO:0016324=IDA, GO:0006855=IC, GO:0016021=IEA, GO:0015893=IC, GO:0015879=IMP, GO:0006814=IEA, GO:0042895=IEA, GO:0015238=IC, GO:0015226=IMP, GO:0015293=IEA} carnitine transport, drug transmembrane transport, drug transport, positive regulation of intestinal epithelial structure maintenance, quaternary ammonium group transport, quorum sensing involved in interaction with host, sodium ion transport, sodium-dependent organic cation transport, transmembrane transport apical plasma membrane, basolateral plasma membrane, brush border membrane, integral to membrane, plasma membrane ATP binding, PDZ domain binding, antibiotic transporter activity, carnitine transmembrane transporter activity, drug transmembrane transporter activity, protein binding, quaternary ammonium group transmembrane transporter activity, symporter activity, transmembrane transporter activity Human GO:0015226 SLC22A6 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0005886=Reactome:REACT_22250, GO:0015347=GO_REF:0000019, GO:0097254=PMID:9887087, GO:0031427=GO_REF:0000019, GO:0043252=GO_REF:0000019, GO:0015742=PMID:9950961, GO:0055085=Reactome:REACT_19118, GO:0043234=GO_REF:0000019, GO:0016323=PMID:15037815, GO:0005452=PMID:15037815, GO:0005887=PMID:14749323, GO:0005901=GO_REF:0000019, GO:0015711=PMID:10049739, GO:0008514=PMID:16024787} Q4U2R8 Solute carrier family 22 member 6 protein 20130415 {GO:0005515=IPI, GO:0005886=TAS, GO:0015347=IEA, GO:0097254=NAS, GO:0031427=IEA, GO:0043252=IEA, GO:0015742=IDA, GO:0055085=TAS, GO:0043234=IEA, GO:0016323=IDA, GO:0005452=IDA, GO:0005887=IDA, GO:0005901=IEA, GO:0015711=IDA, GO:0008514=IDA} alpha-ketoglutarate transport, organic anion transport, renal tubular secretion, response to methotrexate, sodium-independent organic anion transport, transmembrane transport basolateral plasma membrane, caveola, integral to plasma membrane, plasma membrane, protein complex inorganic anion exchanger activity, organic anion transmembrane transporter activity, protein binding, sodium-independent organic anion transmembrane transporter activity Human UniProtKB:Q92624 SLC22A9 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0055085=GO_REF:0000002} Q8IVM8 Solute carrier family 22 member 9 protein 20130413 {GO:0016021=IEA, GO:0055085=IEA} transmembrane transport integral to membrane Human UniProtKB-KW:KW-0812 SLC23A1 GOC UniProtKB {GO:0005515=PMID:17474147, GO:0005215=GO_REF:0000002, GO:0005886=Reactome:REACT_11120, GO:0015882=PMID:19216494, GO:0030324=GO_REF:0000019, GO:0070890=PMID:11895172, GO:0006767=Reactome:REACT_11238, GO:0044281=Reactome:REACT_111217, GO:0070837=PMID:18247577, GO:0016324=PMID:15993839, GO:0005737=GO_REF:0000024, GO:0009925=GO_REF:0000019, GO:0043229=PMID:15993839, GO:0035725=PMID:18094143, GO:0015205=PMID:10395795, GO:0006814=PMID:18094143, GO:0015229=PMID:19216494, GO:0070904=PMID:18417304, GO:0015851=PMID:10395795, GO:0009636=PMID:17575980, GO:0015081=PMID:18094143, GO:0055085=GO_REF:0000002, GO:0019852=Reactome:REACT_11202, GO:0005903=GO_REF:0000019, GO:0008520=PMID:18094143, GO:0006139=PMID:9804989, GO:0016020=PMID:9804989, GO:0007420=GO_REF:0000024, GO:0005887=PMID:10395795, GO:0006766=Reactome:REACT_11193, GO:0033300=PMID:18247577} Q9UHI7 Solute carrier family 23 member 1 protein 20130413 {GO:0005515=IPI, GO:0005215=IEA, GO:0005886=TAS, GO:0015882=IDA, GO:0030324=IEA, GO:0070890=IDA, GO:0006767=TAS, GO:0044281=TAS, GO:0070837=IMP, GO:0016324=IDA, GO:0005737=ISS, GO:0009925=IEA, GO:0043229=IDA, GO:0035725=IDA, GO:0015205=TAS, GO:0006814=IDA, GO:0015229=IDA, GO:0070904=IDA, GO:0015851=TAS, GO:0009636=IDA, GO:0015081=IDA, GO:0055085=IEA, GO:0019852=TAS, GO:0005903=IEA, GO:0008520=IDA, GO:0006139=TAS, GO:0016020=TAS, GO:0007420=ISS, GO:0005887=TAS, GO:0006766=TAS, GO:0033300=IMP} L-ascorbic acid metabolic process, L-ascorbic acid transport, brain development, dehydroascorbic acid transport, lung development, nucleobase transport, nucleobase-containing compound metabolic process, response to toxic substance, small molecule metabolic process, sodium ion transmembrane transport, sodium ion transport, transepithelial L-ascorbic acid transport, transmembrane transport, vitamin metabolic process, water-soluble vitamin metabolic process apical plasma membrane, basal plasma membrane, brush border, cytoplasm, integral to plasma membrane, intracellular organelle, membrane, plasma membrane L-ascorbate:sodium symporter activity, L-ascorbic acid transporter activity, dehydroascorbic acid transporter activity, nucleobase transmembrane transporter activity, protein binding, sodium ion transmembrane transporter activity, sodium-dependent L-ascorbate transmembrane transporter activity, transporter activity Human SLC23A2 Reactome UniProtKB {GO:0005215=GO_REF:0000002, GO:0005886=Reactome:REACT_11120, GO:0015882=PMID:18417304, GO:0070890=PMID:15993839, GO:0006767=Reactome:REACT_11238, GO:0044281=Reactome:REACT_111217, GO:0016323=PMID:15993839, GO:0005737=GO_REF:0000019, GO:0016324=PMID:18417304, GO:0009925=GO_REF:0000019, GO:0015205=PMID:9804989, GO:0015229=PMID:18417304, GO:0006979=GO_REF:0000019, GO:0070904=PMID:18417304, GO:0015851=PMID:9804989, GO:0055085=GO_REF:0000002, GO:0019852=Reactome:REACT_11202, GO:0008520=GO_REF:0000019, GO:0006139=PMID:9804989, GO:0016020=PMID:9804989, GO:0005887=GO_REF:0000019, GO:0006766=Reactome:REACT_11193, GO:0008523=PMID:10471399, GO:0016021=PMID:10471399, GO:0015993=PMID:10471399} Q9UGH3 Solute carrier family 23 member 2 protein 20130301 {GO:0005215=IEA, GO:0005886=TAS, GO:0015882=IDA, GO:0070890=IDA, GO:0006767=TAS, GO:0044281=TAS, GO:0016323=IDA, GO:0005737=IEA, GO:0016324=IDA, GO:0009925=IEA, GO:0015205=TAS, GO:0015229=IDA, GO:0006979=IEA, GO:0070904=IDA, GO:0015851=TAS, GO:0055085=IEA, GO:0019852=TAS, GO:0008520=IEA, GO:0006139=TAS, GO:0016020=TAS, GO:0005887=IEA, GO:0006766=TAS, GO:0008523=NAS, GO:0016021=NAS, GO:0015993=NAS} L-ascorbic acid metabolic process, L-ascorbic acid transport, molecular hydrogen transport, nucleobase transport, nucleobase-containing compound metabolic process, response to oxidative stress, small molecule metabolic process, transepithelial L-ascorbic acid transport, transmembrane transport, vitamin metabolic process, water-soluble vitamin metabolic process apical plasma membrane, basal plasma membrane, basolateral plasma membrane, cytoplasm, integral to membrane, integral to plasma membrane, membrane, plasma membrane L-ascorbate:sodium symporter activity, L-ascorbic acid transporter activity, nucleobase transmembrane transporter activity, sodium-dependent L-ascorbate transmembrane transporter activity, sodium-dependent multivitamin transmembrane transporter activity, transporter activity Human SLC23A3 InterPro UniProtKB {GO:0005215=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0055085=GO_REF:0000002} Q6ZV11 Solute carrier family 23 member 3 protein 20130413 {GO:0005215=IEA, GO:0016020=IEA, GO:0016021=IEA, GO:0055085=IEA} transmembrane transport integral to membrane, membrane transporter activity Human InterPro:IPR006043 SLC24A1 UniProtKB UniProtKB {GO:0005515=PMID:17474147, GO:0005886=Reactome:REACT_19339, GO:0009642=PMID:9856482, GO:0055085=Reactome:REACT_19118, GO:0016020=PMID:9478004, GO:0005887=PMID:9478004, GO:0019867=PMID:9856482, GO:0006810=PMID:9478004, GO:0006816=PMID:7539424, GO:0016021=GO_REF:0000038, GO:0007601=GO_REF:0000002, GO:0015293=GO_REF:0000037, GO:0006811=Reactome:REACT_19397, GO:0008273=GO_REF:0000002} Q17RM9 Sodium/potassium/calcium exchanger 1 protein 20130413 {GO:0005515=IPI, GO:0005886=TAS, GO:0009642=NAS, GO:0055085=TAS, GO:0016020=TAS, GO:0005887=TAS, GO:0019867=NAS, GO:0006810=TAS, GO:0006816=NAS, GO:0016021=IEA, GO:0007601=IEA, GO:0015293=IEA, GO:0006811=TAS, GO:0008273=IEA} calcium ion transport, ion transport, response to light intensity, transmembrane transport, transport, visual perception integral to membrane, integral to plasma membrane, membrane, outer membrane, plasma membrane calcium, potassium:sodium antiporter activity, protein binding, symporter activity Human UniProtKB-KW:KW-0812 SLC24A2 Reactome UniProtKB {GO:0005262=GO_REF:0000019, GO:0005886=Reactome:REACT_19339, GO:0006874=GO_REF:0000019, GO:0060291=GO_REF:0000019, GO:0060292=GO_REF:0000019, GO:0055085=Reactome:REACT_19118, GO:0015297=GO_REF:0000037, GO:0046983=GO_REF:0000019, GO:0007613=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007612=GO_REF:0000019, GO:0006814=GO_REF:0000037, GO:0006813=GO_REF:0000037, GO:0007601=GO_REF:0000037, GO:0006811=Reactome:REACT_19397, GO:0015293=GO_REF:0000037} Q9UI40 Sodium/potassium/calcium exchanger 2 protein 20130301 {GO:0005262=IEA, GO:0005886=TAS, GO:0006874=IEA, GO:0060291=IEA, GO:0060292=IEA, GO:0055085=TAS, GO:0015297=IEA, GO:0046983=IEA, GO:0007613=IEA, GO:0016021=IEA, GO:0007612=IEA, GO:0006814=IEA, GO:0006813=IEA, GO:0007601=IEA, GO:0006811=TAS, GO:0015293=IEA} cellular calcium ion homeostasis, ion transport, learning, long term synaptic depression, long-term synaptic potentiation, memory, potassium ion transport, sodium ion transport, transmembrane transport, visual perception integral to membrane, plasma membrane antiporter activity, calcium channel activity, protein dimerization activity, symporter activity Human SLC24A6 Reactome UniProtKB {GO:0042383=GO_REF:0000019, GO:0005886=Reactome:REACT_19367, GO:0050796=PMID:23056385, GO:0006851=PMID:20018762, GO:0032592=PMID:23056385, GO:0005743=GO_REF:0000039, GO:0042593=PMID:23056385, GO:0016021=GO_REF:0000038, GO:0055085=Reactome:REACT_19118, GO:0005432=PMID:23056385, GO:0050896=GO_REF:0000037, GO:0006811=Reactome:REACT_19397} Q6J4K2 Sodium/potassium/calcium exchanger 6, mitochondrial protein 20130301 {GO:0042383=IEA, GO:0005886=TAS, GO:0050796=IDA, GO:0006851=IMP, GO:0032592=IDA, GO:0005743=IEA, GO:0042593=IDA, GO:0016021=IEA, GO:0055085=TAS, GO:0005432=IDA, GO:0050896=IEA, GO:0006811=TAS} glucose homeostasis, ion transport, mitochondrial calcium ion transport, regulation of insulin secretion, response to stimulus, transmembrane transport integral to membrane, integral to mitochondrial membrane, mitochondrial inner membrane, plasma membrane, sarcolemma calcium:sodium antiporter activity Human SLC25A1 Reactome UniProtKB {GO:0005975=Reactome:REACT_474, GO:0006843=GO_REF:0000029, GO:0015137=PMID:8666394, GO:0019432=Reactome:REACT_1190, GO:0006094=Reactome:REACT_1520, GO:0005743=Reactome:REACT_14780, GO:0006810=GO_REF:0000038, GO:0006006=Reactome:REACT_723, GO:0044281=Reactome:REACT_111217, GO:0035338=Reactome:REACT_1319, GO:0016021=GO_REF:0000037, GO:0044255=Reactome:REACT_22279} P53007 Tricarboxylate transport protein, mitochondrial protein 20130301 {GO:0005975=TAS, GO:0006843=TAS, GO:0015137=TAS, GO:0019432=TAS, GO:0006094=TAS, GO:0005743=TAS, GO:0006810=IEA, GO:0006006=TAS, GO:0044281=TAS, GO:0035338=TAS, GO:0016021=IEA, GO:0044255=TAS} carbohydrate metabolic process, cellular lipid metabolic process, gluconeogenesis, glucose metabolic process, long-chain fatty-acyl-CoA biosynthetic process, mitochondrial citrate transport, small molecule metabolic process, transport, triglyceride biosynthetic process integral to membrane, mitochondrial inner membrane citrate transmembrane transporter activity Human SLC25A10 HPA UniProtKB {GO:0005515=PMID:19447967, GO:0005310=PMID:9733776, GO:0003735=GO_REF:0000002, GO:0031966=GO_REF:0000002, GO:0005975=Reactome:REACT_474, GO:0006094=Reactome:REACT_1520, GO:0005743=Reactome:REACT_115667, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0055085=Reactome:REACT_19118, GO:0006412=GO_REF:0000002, GO:0005739=GO_REF:0000052, GO:0034641=Reactome:REACT_13, GO:0000096=Reactome:REACT_115639, GO:0000098=Reactome:REACT_115654, GO:0006810=GO_REF:0000038, GO:0006006=Reactome:REACT_723, GO:0005840=GO_REF:0000002, GO:0006835=PMID:9733776, GO:0016021=GO_REF:0000037, GO:0070221=Reactome:REACT_116010, GO:0006839=GO_REF:0000002, GO:0006811=Reactome:REACT_19397} Q9UBX3 Mitochondrial dicarboxylate carrier protein 20101115 {GO:0005515=IPI, GO:0005310=TAS, GO:0003735=IEA, GO:0031966=IEA, GO:0005975=TAS, GO:0006094=TAS, GO:0005743=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0055085=TAS, GO:0006412=IEA, GO:0005739=IDA, GO:0034641=TAS, GO:0000096=TAS, GO:0000098=TAS, GO:0006810=IEA, GO:0006006=TAS, GO:0005840=IEA, GO:0006835=TAS, GO:0016021=IEA, GO:0070221=TAS, GO:0006839=IEA, GO:0006811=TAS} carbohydrate metabolic process, cellular nitrogen compound metabolic process, dicarboxylic acid transport, gluconeogenesis, glucose metabolic process, ion transport, mitochondrial transport, small molecule metabolic process, sulfide oxidation, using sulfide:quinone oxidoreductase, sulfur amino acid catabolic process, sulfur amino acid metabolic process, translation, transmembrane transport, transport integral to membrane, mitochondrial inner membrane, mitochondrial membrane, mitochondrion, nucleolus, nucleus, ribosome dicarboxylic acid transmembrane transporter activity, protein binding, structural constituent of ribosome Human SLC25A11 GOC UniProtKB {GO:0005975=Reactome:REACT_474, GO:0005887=PMID:1457818, GO:0015367=Reactome:REACT_11181, GO:0006094=Reactome:REACT_1520, GO:0005743=Reactome:REACT_11181, GO:0006810=PMID:1457818, GO:0006006=Reactome:REACT_723, GO:0015742=Reactome:REACT_11181, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000038} Q02978 Mitochondrial 2-oxoglutarate/malate carrier protein protein 20130413 {GO:0005975=TAS, GO:0005887=TAS, GO:0015367=TAS, GO:0006094=TAS, GO:0005743=TAS, GO:0006810=TAS, GO:0006006=TAS, GO:0015742=TAS, GO:0044281=TAS, GO:0016021=IEA} alpha-ketoglutarate transport, carbohydrate metabolic process, gluconeogenesis, glucose metabolic process, small molecule metabolic process, transport integral to membrane, integral to plasma membrane, mitochondrial inner membrane oxoglutarate:malate antiporter activity Human SLC25A12 Reactome UniProtKB {GO:0005975=Reactome:REACT_474, GO:0005509=PMID:9722566, GO:0005313=PMID:11566871, GO:0006094=Reactome:REACT_1520, GO:0005743=Reactome:REACT_14830, GO:0044281=Reactome:REACT_111217, GO:0055085=GO_REF:0000002, GO:0005739=PMID:9722566, GO:0015813=PMID:11566871, GO:0051592=PMID:11566871, GO:0015810=PMID:11566871, GO:0015183=PMID:11566871, GO:0043490=PMID:11566871, GO:0006006=Reactome:REACT_723, GO:0016021=PMID:9722566} O75746 Calcium-binding mitochondrial carrier protein Aralar1 protein 20130301 {GO:0005975=TAS, GO:0005509=IDA, GO:0005313=IDA, GO:0006094=TAS, GO:0005743=TAS, GO:0044281=TAS, GO:0055085=IEA, GO:0005739=IDA, GO:0015813=IDA, GO:0051592=IDA, GO:0015810=IDA, GO:0015183=IDA, GO:0043490=IDA, GO:0006006=TAS, GO:0016021=NAS} L-glutamate transport, aspartate transport, carbohydrate metabolic process, gluconeogenesis, glucose metabolic process, malate-aspartate shuttle, response to calcium ion, small molecule metabolic process, transmembrane transport integral to membrane, mitochondrial inner membrane, mitochondrion L-aspartate transmembrane transporter activity, L-glutamate transmembrane transporter activity, calcium ion binding Human SLC25A13 HPA UniProtKB {GO:0005215=PMID:10642534, GO:0005975=Reactome:REACT_474, GO:0005509=PMID:10642534, GO:0005313=PMID:11566871, GO:0006094=Reactome:REACT_1520, GO:0005743=Reactome:REACT_14830, GO:0044281=Reactome:REACT_111217, GO:0055085=GO_REF:0000002, GO:0005739=GO_REF:0000052, GO:0051592=PMID:11566871, GO:0015813=PMID:11566871, GO:0006754=PMID:12851387, GO:0045333=PMID:12851387, GO:0015810=PMID:11566871, GO:0015183=PMID:11566871, GO:0005887=PMID:10642534, GO:0006810=PMID:10642534, GO:0006006=Reactome:REACT_723, GO:0043490=PMID:11566871, GO:0016021=GO_REF:0000038} Q9UJS0 Calcium-binding mitochondrial carrier protein Aralar2 protein 20100326 {GO:0005215=NAS, GO:0005975=TAS, GO:0005509=IDA, GO:0005313=IDA, GO:0006094=TAS, GO:0005743=TAS, GO:0044281=TAS, GO:0055085=IEA, GO:0005739=IDA, GO:0051592=IDA, GO:0015813=IDA, GO:0006754=IDA, GO:0045333=IDA, GO:0015810=IDA, GO:0015183=IDA, GO:0005887=NAS, GO:0006810=NAS, GO:0006006=TAS, GO:0043490=IDA, GO:0016021=IEA} ATP biosynthetic process, L-glutamate transport, aspartate transport, carbohydrate metabolic process, cellular respiration, gluconeogenesis, glucose metabolic process, malate-aspartate shuttle, response to calcium ion, small molecule metabolic process, transmembrane transport, transport integral to membrane, integral to plasma membrane, mitochondrial inner membrane, mitochondrion L-aspartate transmembrane transporter activity, L-glutamate transmembrane transporter activity, calcium ion binding, transporter activity Human SLC25A15 Reactome UniProtKB {GO:0034641=Reactome:REACT_13, GO:0006520=PMID:10369256, GO:0000050=Reactome:REACT_847, GO:0005743=Reactome:REACT_151, GO:0006810=GO_REF:0000038, GO:0000066=PMID:10369256, GO:0044281=Reactome:REACT_111217, GO:0000064=PMID:10369256, GO:0016021=GO_REF:0000037} Q9Y619 Mitochondrial ornithine transporter 1 protein 20130301 {GO:0034641=TAS, GO:0006520=TAS, GO:0000050=TAS, GO:0005743=TAS, GO:0006810=IEA, GO:0000066=TAS, GO:0044281=TAS, GO:0000064=TAS, GO:0016021=IEA} cellular amino acid metabolic process, cellular nitrogen compound metabolic process, mitochondrial ornithine transport, small molecule metabolic process, transport, urea cycle integral to membrane, mitochondrial inner membrane L-ornithine transmembrane transporter activity Human SLC25A17 GOC UniProtKB {GO:0005515=PMID:14709540, GO:0005215=GO_REF:0000002, GO:0043132=PMID:22185573, GO:0015230=PMID:22185573, GO:0005743=GO_REF:0000002, GO:0051087=PMID:11402059, GO:0044281=Reactome:REACT_111217, GO:0005739=GO_REF:0000019, GO:0001561=Reactome:REACT_17003, GO:0006810=GO_REF:0000038, GO:0015228=PMID:22185573, GO:0005779=PMID:11121399, GO:0006839=GO_REF:0000002, GO:0051724=PMID:22185573, GO:0005778=Reactome:REACT_16948, GO:0044255=Reactome:REACT_16957, GO:0005777=PMID:9874197, GO:0031966=GO_REF:0000002, GO:0006635=PMID:12445829, GO:0044610=PMID:22185573, GO:0035349=PMID:22185573, GO:0055085=GO_REF:0000002, GO:0035350=PMID:22185573, GO:0015866=PMID:22185573, GO:0015867=PMID:12445829, GO:0080122=PMID:22185573, GO:0015217=PMID:22185573, GO:0080121=PMID:22185573, GO:0016021=GO_REF:0000038, GO:0015908=PMID:12445829, GO:0005347=PMID:12445829} O43808 Peroxisomal membrane protein PMP34 protein 20130413 {GO:0005515=IPI, GO:0005215=IEA, GO:0043132=IDA, GO:0015230=IDA, GO:0005743=IEA, GO:0051087=IPI, GO:0044281=TAS, GO:0005739=IEA, GO:0001561=TAS, GO:0006810=IEA, GO:0015228=IDA, GO:0005779=IDA, GO:0006839=IEA, GO:0051724=IDA, GO:0005778=TAS, GO:0044255=TAS, GO:0005777=IDA, GO:0031966=IEA, GO:0006635=IGI, GO:0044610=IDA, GO:0035349=IDA, GO:0055085=IEA, GO:0035350=IDA, GO:0015866=IDA, GO:0015867=IGI, GO:0080122=IDA, GO:0015217=IDA, GO:0080121=IDA, GO:0016021=IEA, GO:0015908=IGI, GO:0005347=IGI} ADP transport, AMP transport, ATP transport, FAD transmembrane transport, NAD transport, cellular lipid metabolic process, coenzyme A transmembrane transport, fatty acid alpha-oxidation, fatty acid beta-oxidation, fatty acid transport, mitochondrial transport, small molecule metabolic process, transmembrane transport, transport integral to membrane, integral to peroxisomal membrane, mitochondrial inner membrane, mitochondrial membrane, mitochondrion, peroxisomal membrane, peroxisome ADP transmembrane transporter activity, AMP transmembrane transporter activity, ATP transmembrane transporter activity, FAD transmembrane transporter activity, FMN transmembrane transporter activity, NAD transporter activity, chaperone binding, coenzyme A transmembrane transporter activity, protein binding, transporter activity Human SLC25A18 UniProtKB UniProtKB {GO:0005743=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0015293=GO_REF:0000037} Q9H1K4 Mitochondrial glutamate carrier 2 protein 20130413 {GO:0005743=IEA, GO:0016021=IEA, GO:0015293=IEA} integral to membrane, mitochondrial inner membrane symporter activity Human UniProtKB-SubCell:SL-0168 SLC25A19 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0030302=PMID:11226231, GO:0005743=GO_REF:0000029, GO:0006810=GO_REF:0000038, GO:0016021=GO_REF:0000037, GO:0030233=PMID:11226231} Q9HC21 Mitochondrial thiamine pyrophosphate carrier protein 20011004 {GO:0005739=IEA, GO:0030302=NAS, GO:0005743=NAS, GO:0006810=IEA, GO:0016021=IEA, GO:0030233=TAS} deoxynucleotide transport, transport integral to membrane, mitochondrial inner membrane, mitochondrion deoxynucleotide transmembrane transporter activity Human SLC25A20 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0006853=Reactome:REACT_11082, GO:0005743=Reactome:REACT_11180, GO:0006810=GO_REF:0000038, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0044255=Reactome:REACT_22279} O43772 Mitochondrial carnitine/acylcarnitine carrier protein protein 20111111 {GO:0005739=IDA, GO:0005737=IDA, GO:0006853=TAS, GO:0005743=TAS, GO:0006810=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0044255=TAS} carnitine shuttle, cellular lipid metabolic process, small molecule metabolic process, transport cytoplasm, integral to membrane, mitochondrial inner membrane, mitochondrion Human SLC25A21 Reactome UniProtKB {GO:0005739=GO_REF:0000019, GO:0034641=Reactome:REACT_13, GO:0005743=Reactome:REACT_14838, GO:0044281=Reactome:REACT_111217, GO:0006554=Reactome:REACT_1298, GO:0016021=GO_REF:0000037, GO:0055085=GO_REF:0000002} Q9BQT8 Mitochondrial 2-oxodicarboxylate carrier protein 20130301 {GO:0005739=IEA, GO:0034641=TAS, GO:0005743=TAS, GO:0044281=TAS, GO:0006554=TAS, GO:0016021=IEA, GO:0055085=IEA} cellular nitrogen compound metabolic process, lysine catabolic process, small molecule metabolic process, transmembrane transport integral to membrane, mitochondrial inner membrane, mitochondrion Human SLC25A22 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0015813=PMID:11897791, GO:0005313=PMID:11897791, GO:0005743=PMID:11897791, GO:0006810=GO_REF:0000038, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0016021=GO_REF:0000037, GO:0055085=GO_REF:0000002, GO:0015293=GO_REF:0000037} Q9H936 Mitochondrial glutamate carrier 1 protein 20101115 {GO:0005739=IDA, GO:0015813=IDA, GO:0005313=IDA, GO:0005743=IDA, GO:0006810=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0016021=IEA, GO:0055085=IEA, GO:0015293=IEA} L-glutamate transport, transmembrane transport, transport integral to membrane, mitochondrial inner membrane, mitochondrion, nucleolus, nucleus L-glutamate transmembrane transporter activity, symporter activity Human SLC25A23 UniProtKB UniProtKB {GO:0005509=GO_REF:0000002, GO:0005743=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0055085=GO_REF:0000002} Q9BV35 Calcium-binding mitochondrial carrier protein SCaMC-3 protein 20130413 {GO:0005509=IEA, GO:0005743=IEA, GO:0016021=IEA, GO:0055085=IEA} transmembrane transport integral to membrane, mitochondrial inner membrane calcium ion binding Human UniProtKB-SubCell:SL-0168 SLC25A24 UniProtKB UniProtKB {GO:0005509=GO_REF:0000002, GO:0005743=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0055085=GO_REF:0000002} Q6NUK1 Calcium-binding mitochondrial carrier protein SCaMC-1 protein 20130413 {GO:0005509=IEA, GO:0005743=IEA, GO:0016021=IEA, GO:0055085=IEA} transmembrane transport integral to membrane, mitochondrial inner membrane calcium ion binding Human UniProtKB-SubCell:SL-0168 SLC25A25 UniProtKB UniProtKB {GO:0005509=GO_REF:0000002, GO:0005743=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0055085=GO_REF:0000002} Q6KCM7 Calcium-binding mitochondrial carrier protein SCaMC-2 protein 20130413 {GO:0005509=IEA, GO:0005743=IEA, GO:0016021=IEA, GO:0055085=IEA} transmembrane transport integral to membrane, mitochondrial inner membrane calcium ion binding Human UniProtKB-SubCell:SL-0168 SLC25A26 GOC UniProtKB {GO:0015805=PMID:14674884, GO:0005739=GO_REF:0000052, GO:0000095=PMID:14674884, GO:1901962=PMID:14674884, GO:0005743=PMID:14674884, GO:0005730=GO_REF:0000052, GO:0006810=GO_REF:0000038, GO:0005634=GO_REF:0000052, GO:0016021=GO_REF:0000037} Q70HW3 S-adenosylmethionine mitochondrial carrier protein protein 20130413 {GO:0015805=IMP, GO:0005739=IDA, GO:0000095=IMP, GO:1901962=IMP, GO:0005743=IDA, GO:0005730=IDA, GO:0006810=IEA, GO:0005634=IDA, GO:0016021=IEA} S-adenosyl-L-methionine transmembrane transport, S-adenosyl-L-methionine transport, transport integral to membrane, mitochondrial inner membrane, mitochondrion, nucleolus, nucleus S-adenosyl-L-methionine transmembrane transporter activity Human SLC25A27 UniProtKB UniProtKB {GO:0008284=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0048839=GO_REF:0000019, GO:0005743=GO_REF:0000039, GO:0045177=GO_REF:0000019, GO:0035356=GO_REF:0000019, GO:0006091=PMID:10025957, GO:0005739=PMID:10025957, GO:0051562=GO_REF:0000019, GO:0070997=GO_REF:0000019, GO:0006810=GO_REF:0000037, GO:0043025=GO_REF:0000019, GO:0016021=GO_REF:0000038} Q5VTS8 Mitochondrial uncoupling protein 4 protein 20130413 {GO:0008284=IEA, GO:0043066=IEA, GO:0048839=IEA, GO:0005743=IEA, GO:0045177=IEA, GO:0035356=IEA, GO:0006091=TAS, GO:0005739=TAS, GO:0051562=IEA, GO:0070997=IEA, GO:0006810=IEA, GO:0043025=IEA, GO:0016021=IEA} cellular triglyceride homeostasis, generation of precursor metabolites and energy, inner ear development, negative regulation of apoptotic process, neuron death, positive regulation of cell proliferation, reduction of mitochondrial calcium ion concentration, transport apical part of cell, integral to membrane, mitochondrial inner membrane, mitochondrion, neuronal cell body Human UniProtKB-KW:KW-0812 SLC25A28 Reactome UniProtKB {GO:0005743=Reactome:REACT_150305, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0055072=GO_REF:0000037, GO:0006811=GO_REF:0000037} Q96A46 Mitoferrin-2 protein 20130301 {GO:0005743=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0055072=IEA, GO:0006811=IEA} ion transport, iron ion homeostasis, small molecule metabolic process integral to membrane, mitochondrial inner membrane Human SLC25A3 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0015320=PMID:8144629, GO:0005887=PMID:8144629, GO:0005743=GO_REF:0000039, GO:0006810=PMID:1777677, GO:0006091=PMID:8168843, GO:0016021=GO_REF:0000038, GO:0015293=GO_REF:0000037} Q00325 Phosphate carrier protein, mitochondrial protein 20111111 {GO:0005739=IDA, GO:0015320=TAS, GO:0005887=TAS, GO:0005743=IEA, GO:0006810=TAS, GO:0006091=TAS, GO:0016021=IEA, GO:0015293=IEA} generation of precursor metabolites and energy, transport integral to membrane, integral to plasma membrane, mitochondrial inner membrane, mitochondrion phosphate ion carrier activity, symporter activity Human SLC25A30 BHF-UCL UniProtKB {GO:0005739=PMID:15809292, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0031966=GO_REF:0000002, GO:0005743=GO_REF:0000039, GO:0006810=GO_REF:0000038, GO:0016021=GO_REF:0000037, GO:0006839=GO_REF:0000002} Q5SVS4 Kidney mitochondrial carrier protein 1 protein 20110722 {GO:0005739=ISS, GO:0003674=ND, GO:0008150=ND, GO:0031966=IEA, GO:0005743=IEA, GO:0006810=IEA, GO:0016021=IEA, GO:0006839=IEA} biological_process, mitochondrial transport, transport integral to membrane, mitochondrial inner membrane, mitochondrial membrane, mitochondrion molecular_function Human SLC25A31 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005929=GO_REF:0000037, GO:0005215=GO_REF:0000002, GO:0005743=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0055085=GO_REF:0000002} Q9H0C2 ADP/ATP translocase 4 protein 20090616 {GO:0005739=IDA, GO:0005929=IEA, GO:0005215=IEA, GO:0005743=IEA, GO:0016021=IEA, GO:0055085=IEA} transmembrane transport cilium, integral to membrane, mitochondrial inner membrane, mitochondrion transporter activity Human SLC25A32 Reactome UniProtKB {GO:0005739=GO_REF:0000019, GO:0006766=Reactome:REACT_11193, GO:0015884=PMID:10978331, GO:0005743=Reactome:REACT_11219, GO:0006810=GO_REF:0000038, GO:0006767=Reactome:REACT_11238, GO:0046655=Reactome:REACT_11167, GO:0044281=Reactome:REACT_111217, GO:0008517=PMID:10978331, GO:0016021=GO_REF:0000037, GO:0006839=GO_REF:0000002} Q9H2D1 Mitochondrial folate transporter/carrier protein 20130301 {GO:0005739=IEA, GO:0006766=TAS, GO:0015884=NAS, GO:0005743=TAS, GO:0006810=IEA, GO:0006767=TAS, GO:0046655=TAS, GO:0044281=TAS, GO:0008517=NAS, GO:0016021=IEA, GO:0006839=IEA} folic acid metabolic process, folic acid transport, mitochondrial transport, small molecule metabolic process, transport, vitamin metabolic process, water-soluble vitamin metabolic process integral to membrane, mitochondrial inner membrane, mitochondrion folic acid transporter activity Human SLC25A33 UniProtKB UniProtKB {GO:0005743=GO_REF:0000039, GO:0006810=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q9BSK2 Solute carrier family 25 member 33 protein 20130413 {GO:0005743=IEA, GO:0006810=IEA, GO:0016021=IEA} transport integral to membrane, mitochondrial inner membrane Human UniProtKB-SubCell:SL-0168 SLC25A34 UniProtKB UniProtKB {GO:0005743=GO_REF:0000039, GO:0006810=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q6PIV7 Solute carrier family 25 member 34 protein 20130413 {GO:0005743=IEA, GO:0006810=IEA, GO:0016021=IEA} transport integral to membrane, mitochondrial inner membrane Human UniProtKB-SubCell:SL-0168 SLC25A36 BHF-UCL UniProtKB {GO:0005743=GO_REF:0000039, GO:0006810=GO_REF:0000038, GO:0016021=GO_REF:0000037, GO:0032355=PMID:15831516, GO:0055085=GO_REF:0000002} Q96CQ1 Solute carrier family 25 member 36 protein 20080716 {GO:0005743=IEA, GO:0006810=IEA, GO:0016021=IEA, GO:0032355=IDA, GO:0055085=IEA} response to estradiol stimulus, transmembrane transport, transport integral to membrane, mitochondrial inner membrane Human SLC25A37 Reactome UniProtKB {GO:0048250=GO_REF:0000019, GO:0005743=Reactome:REACT_150305, GO:0005381=GO_REF:0000019, GO:0006810=GO_REF:0000038, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0055072=GO_REF:0000037} Q9NYZ2 Mitoferrin-1 protein 20130301 {GO:0048250=IEA, GO:0005743=TAS, GO:0005381=IEA, GO:0006810=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0055072=IEA} iron ion homeostasis, mitochondrial iron ion transport, small molecule metabolic process, transport integral to membrane, mitochondrial inner membrane iron ion transmembrane transporter activity Human SLC25A38 UniProtKB UniProtKB {GO:0030218=PMID:19412178, GO:0005743=GO_REF:0000039, GO:0006810=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0006783=PMID:19412178} Q96DW6 Solute carrier family 25 member 38 protein 20090508 {GO:0030218=IMP, GO:0005743=IEA, GO:0006810=IEA, GO:0016021=IEA, GO:0006783=TAS} erythrocyte differentiation, heme biosynthetic process, transport integral to membrane, mitochondrial inner membrane Human SLC25A39 UniProtKB UniProtKB {GO:0005743=GO_REF:0000039, GO:0006810=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0055085=GO_REF:0000002, GO:0006783=GO_REF:0000037} Q9BZJ4 Solute carrier family 25 member 39 protein 20130413 {GO:0005743=IEA, GO:0006810=IEA, GO:0016021=IEA, GO:0055085=IEA, GO:0006783=IEA} heme biosynthetic process, transmembrane transport, transport integral to membrane, mitochondrial inner membrane Human UniProtKB-SubCell:SL-0168 SLC25A4 GOC UniProtKB {GO:0005515=PMID:16507998, GO:0005743=Reactome:REACT_9011, GO:0006091=PMID:2823266, GO:0044281=Reactome:REACT_111217, GO:0005739=PMID:10926541, GO:0008637=GO_REF:0000019, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0005887=PMID:2823266, GO:0019048=GO_REF:0000037, GO:0006810=PMID:2823266, GO:0016032=Reactome:REACT_6185, GO:0060547=PMID:16507998, GO:0015207=PMID:2823266, GO:0015853=PMID:2823266, GO:0000002=PMID:10926541} P12235 ADP/ATP translocase 1 protein 20130413 {GO:0005515=IPI, GO:0005743=TAS, GO:0006091=TAS, GO:0044281=TAS, GO:0005739=TAS, GO:0008637=IEA, GO:0006112=TAS, GO:0050796=TAS, GO:0005887=TAS, GO:0019048=IEA, GO:0006810=TAS, GO:0016032=TAS, GO:0060547=IMP, GO:0015207=TAS, GO:0015853=TAS, GO:0000002=TAS} adenine transport, apoptotic mitochondrial changes, energy reserve metabolic process, generation of precursor metabolites and energy, mitochondrial genome maintenance, negative regulation of necrotic cell death, regulation of insulin secretion, small molecule metabolic process, transport, viral reproduction, virus-host interaction integral to plasma membrane, mitochondrial inner membrane, mitochondrion adenine transmembrane transporter activity, protein binding Human SLC25A43 UniProtKB UniProtKB {GO:0005743=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0055085=GO_REF:0000002} Q8WUT9 Solute carrier family 25 member 43 protein 20130413 {GO:0005743=IEA, GO:0016021=IEA, GO:0055085=IEA} transmembrane transport integral to membrane, mitochondrial inner membrane Human UniProtKB-SubCell:SL-0168 SLC25A44 UniProtKB UniProtKB {GO:0005743=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0055085=GO_REF:0000002} Q96H78 Solute carrier family 25 member 44 protein 20130413 {GO:0005743=IEA, GO:0016021=IEA, GO:0055085=IEA} transmembrane transport integral to membrane, mitochondrial inner membrane Human UniProtKB-SubCell:SL-0168 SLC25A46 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005743=GO_REF:0000039, GO:0006810=GO_REF:0000037, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} Q96AG3 Solute carrier family 25 member 46 protein 20070906 {GO:0005739=IEA, GO:0003674=ND, GO:0008150=ND, GO:0005743=IEA, GO:0006810=IEA, GO:0005575=ND, GO:0016021=IEA} biological_process, transport cellular_component, integral to membrane, mitochondrial inner membrane, mitochondrion molecular_function Human SLC25A47 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0005743=GO_REF:0000039, GO:0006810=GO_REF:0000038, GO:0016021=GO_REF:0000037, GO:0055085=GO_REF:0000002} Q6Q0C1 Solute carrier family 25 member 47 protein 20130413 {GO:0005739=IEA, GO:0005743=IEA, GO:0006810=IEA, GO:0016021=IEA, GO:0055085=IEA} transmembrane transport, transport integral to membrane, mitochondrial inner membrane, mitochondrion Human UniProtKB-SubCell:SL-0168 SLC25A5 GOC UniProtKB {GO:0042645=PMID:18063578, GO:0005515=PMID:19154410, GO:0008284=PMID:19154410, GO:0005743=Reactome:REACT_9011, GO:1901029=PMID:19154410, GO:0044281=Reactome:REACT_111217, GO:0007059=GO_REF:0000037, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0005887=PMID:2168878, GO:0019048=GO_REF:0000037, GO:0006810=PMID:2168878, GO:0015207=PMID:2168878, GO:0016032=Reactome:REACT_6185, GO:0015853=PMID:2168878, GO:0071817=PMID:20797633} P05141 ADP/ATP translocase 2 protein 20130413 {GO:0042645=IDA, GO:0005515=IPI, GO:0008284=IMP, GO:0005743=TAS, GO:1901029=IMP, GO:0044281=TAS, GO:0007059=IEA, GO:0006112=TAS, GO:0050796=TAS, GO:0005887=TAS, GO:0019048=IEA, GO:0006810=TAS, GO:0015207=TAS, GO:0016032=TAS, GO:0015853=TAS, GO:0071817=IDA} adenine transport, chromosome segregation, energy reserve metabolic process, negative regulation of mitochondrial outer membrane permeabilization, positive regulation of cell proliferation, regulation of insulin secretion, small molecule metabolic process, transport, viral reproduction, virus-host interaction MMXD complex, integral to plasma membrane, mitochondrial inner membrane, mitochondrial nucleoid adenine transmembrane transporter activity, protein binding Human SLC25A6 Reactome UniProtKB {GO:0005215=GO_REF:0000002, GO:0006626=Reactome:REACT_118595, GO:0005743=Reactome:REACT_118697, GO:0019058=Reactome:REACT_6167, GO:0046732=Reactome:REACT_6213, GO:0006915=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0055085=GO_REF:0000002, GO:0005744=PMID:2541251, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0019048=Reactome:REACT_6323, GO:0016032=Reactome:REACT_6185, GO:0016021=GO_REF:0000037, GO:0005471=PMID:2541251, GO:0044267=Reactome:REACT_17015} P12236 ADP/ATP translocase 3 protein 20130213 {GO:0005215=IEA, GO:0006626=TAS, GO:0005743=TAS, GO:0019058=TAS, GO:0046732=TAS, GO:0006915=IEA, GO:0044281=TAS, GO:0055085=IEA, GO:0005744=TAS, GO:0006112=TAS, GO:0050796=TAS, GO:0019048=TAS, GO:0016032=TAS, GO:0016021=IEA, GO:0005471=NAS, GO:0044267=TAS} active induction of host immune response by virus, apoptotic process, cellular protein metabolic process, energy reserve metabolic process, protein targeting to mitochondrion, regulation of insulin secretion, small molecule metabolic process, transmembrane transport, viral infectious cycle, viral reproduction, virus-host interaction integral to membrane, mitochondrial inner membrane, mitochondrial inner membrane presequence translocase complex ATP:ADP antiporter activity, transporter activity Human SLC26A1 Reactome UniProtKB {GO:0005886=Reactome:REACT_19330, GO:0015116=GO_REF:0000029, GO:0019531=GO_REF:0000019, GO:0015108=GO_REF:0000019, GO:0008272=GO_REF:0000029, GO:0008271=GO_REF:0000002, GO:0016021=PMID:11087667, GO:0055085=Reactome:REACT_19118, GO:0006811=Reactome:REACT_19397} Q9H2B4 Sulfate anion transporter 1 protein 20130301 {GO:0005886=TAS, GO:0015116=NAS, GO:0019531=IEA, GO:0015108=IEA, GO:0008272=NAS, GO:0008271=IEA, GO:0016021=TAS, GO:0055085=TAS, GO:0006811=TAS} ion transport, sulfate transport, transmembrane transport integral to membrane, plasma membrane chloride transmembrane transporter activity, oxalate transmembrane transporter activity, secondary active sulfate transmembrane transporter activity, sulfate transmembrane transporter activity Human SLC26A11 UniProtKB UniProtKB {GO:0008509=PMID:12626430, GO:0005794=PMID:12626430, GO:0005886=PMID:12626430, GO:0015116=GO_REF:0000002, GO:0005783=PMID:12626430, GO:0015301=GO_REF:0000037, GO:0008272=PMID:12626430, GO:0008271=GO_REF:0000002, GO:0016021=PMID:12626430, GO:0005765=PMID:20957757} Q86WA9 Sodium-independent sulfate anion transporter protein 20101207 {GO:0008509=IDA, GO:0005794=IDA, GO:0005886=IDA, GO:0015116=IEA, GO:0005783=IDA, GO:0015301=IEA, GO:0008272=IDA, GO:0008271=IEA, GO:0016021=IDA, GO:0005765=IDA} sulfate transport Golgi apparatus, endoplasmic reticulum, integral to membrane, lysosomal membrane, plasma membrane anion transmembrane transporter activity, anion:anion antiporter activity, secondary active sulfate transmembrane transporter activity, sulfate transmembrane transporter activity Human SLC26A2 Reactome UniProtKB {GO:0005886=Reactome:REACT_19330, GO:0016020=PMID:8528239, GO:0015116=PMID:7923357, GO:0001503=GO_REF:0000019, GO:0005887=PMID:8528239, GO:0008272=GO_REF:0000019, GO:0008271=GO_REF:0000002, GO:0055085=Reactome:REACT_19118, GO:0006811=Reactome:REACT_19397} P50443 Sulfate transporter protein 20130301 {GO:0005886=TAS, GO:0016020=TAS, GO:0015116=TAS, GO:0001503=IEA, GO:0005887=TAS, GO:0008272=IEA, GO:0008271=IEA, GO:0055085=TAS, GO:0006811=TAS} ion transport, ossification, sulfate transport, transmembrane transport integral to plasma membrane, membrane, plasma membrane secondary active sulfate transmembrane transporter activity, sulfate transmembrane transporter activity Human SLC26A3 GOC UniProtKB {GO:0003712=PMID:7683425, GO:0006820=PMID:9554749, GO:0007588=PMID:8896562, GO:0005215=PMID:8896562, GO:0006355=PMID:7683425, GO:0003700=PMID:7683425, GO:0005886=Reactome:REACT_19235, GO:0031526=GO_REF:0000019, GO:0055085=Reactome:REACT_19118, GO:0016324=GO_REF:0000039, GO:0016020=PMID:8896562, GO:0015301=GO_REF:0000019, GO:0008272=GO_REF:0000002, GO:0008271=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0006811=Reactome:REACT_19397} P40879 Chloride anion exchanger protein 20130413 {GO:0003712=TAS, GO:0006820=TAS, GO:0007588=TAS, GO:0005215=TAS, GO:0006355=TAS, GO:0003700=TAS, GO:0005886=TAS, GO:0031526=IEA, GO:0055085=TAS, GO:0016324=IEA, GO:0016020=TAS, GO:0015301=IEA, GO:0008272=IEA, GO:0008271=IEA, GO:0016021=IEA, GO:0006811=TAS} anion transport, excretion, ion transport, regulation of transcription, DNA-dependent, sulfate transport, transmembrane transport apical plasma membrane, brush border membrane, integral to membrane, membrane, plasma membrane anion:anion antiporter activity, secondary active sulfate transmembrane transporter activity, sequence-specific DNA binding transcription factor activity, transcription cofactor activity, transporter activity Human SLC26A6 ENSEMBL UniProtKB {GO:0005886=Reactome:REACT_19235, GO:0015116=GO_REF:0000002, GO:0015301=GO_REF:0000019, GO:0015108=GO_REF:0000019, GO:0005887=GO_REF:0000019, GO:0008272=GO_REF:0000002, GO:0015701=GO_REF:0000019, GO:0008271=GO_REF:0000002, GO:0016021=GO_REF:0000002, GO:0055085=Reactome:REACT_19118, GO:0015499=GO_REF:0000019, GO:0006811=Reactome:REACT_19397} Q9NQU1 Putative anion transporter 1 protein 20130413 {GO:0005886=TAS, GO:0015116=IEA, GO:0015301=IEA, GO:0015108=IEA, GO:0005887=IEA, GO:0008272=IEA, GO:0015701=IEA, GO:0008271=IEA, GO:0016021=IEA, GO:0055085=TAS, GO:0015499=IEA, GO:0006811=TAS} bicarbonate transport, ion transport, sulfate transport, transmembrane transport integral to membrane, integral to plasma membrane, plasma membrane anion:anion antiporter activity, chloride transmembrane transporter activity, formate transmembrane transporter activity, secondary active sulfate transmembrane transporter activity, sulfate transmembrane transporter activity Human Ensembl:ENSMUSP00000095979 SLC26A8 IntAct UniProtKB {GO:0005515=PMID:22121115, GO:0006821=PMID:1183472, GO:0019531=PMID:1183472, GO:0005886=PMID:11278976, GO:0019532=PMID:1183472, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0005254=PMID:1183472, GO:0030154=GO_REF:0000037, GO:0007126=GO_REF:0000037, GO:0015116=PMID:1183472, GO:0015301=GO_REF:0000037, GO:0008272=PMID:1183472, GO:0016021=GO_REF:0000037} Q96RN1 Testis anion transporter 1 protein 20130415 {GO:0005515=IPI, GO:0006821=IDA, GO:0019531=IDA, GO:0005886=IDA, GO:0019532=IDA, GO:0007275=IEA, GO:0007283=IEA, GO:0005254=IDA, GO:0030154=IEA, GO:0007126=IEA, GO:0015116=IDA, GO:0015301=IEA, GO:0008272=IDA, GO:0016021=IEA} cell differentiation, chloride transport, meiosis, multicellular organismal development, oxalate transport, spermatogenesis, sulfate transport integral to membrane, plasma membrane anion:anion antiporter activity, chloride channel activity, oxalate transmembrane transporter activity, protein binding, sulfate transmembrane transporter activity Human UniProtKB:P13569 SLC27A1 Reactome UniProtKB {GO:0001579=GO_REF:0000019, GO:0006646=PMID:19523918, GO:0071902=GO_REF:0000019, GO:0005886=Reactome:REACT_115979, GO:0033211=GO_REF:0000019, GO:0005783=GO_REF:0000019, GO:0009409=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0042803=GO_REF:0000019, GO:0000166=GO_REF:0000037, GO:0006631=GO_REF:0000037, GO:0032049=PMID:19523918, GO:0031957=GO_REF:0000019, GO:0006654=PMID:19523918, GO:0044255=Reactome:REACT_22279, GO:0006655=PMID:19523918, GO:0006656=PMID:19523918, GO:0015245=GO_REF:0000019, GO:0032868=GO_REF:0000019, GO:0006661=PMID:19523918, GO:0071072=PMID:19523918, GO:0055085=Reactome:REACT_19118, GO:0012505=GO_REF:0000039, GO:0031652=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0015909=Reactome:REACT_23892, GO:0006659=PMID:19523918} Q6PCB7 Long-chain fatty acid transport protein 1 protein 20130301 {GO:0001579=IEA, GO:0006646=IMP, GO:0071902=IEA, GO:0005886=TAS, GO:0033211=IEA, GO:0005783=IEA, GO:0009409=IEA, GO:0044281=TAS, GO:0003824=IEA, GO:0042803=IEA, GO:0000166=IEA, GO:0006631=IEA, GO:0032049=IMP, GO:0031957=IEA, GO:0006654=IMP, GO:0044255=TAS, GO:0006655=IMP, GO:0006656=IMP, GO:0015245=IEA, GO:0032868=IEA, GO:0006661=IMP, GO:0071072=IMP, GO:0055085=TAS, GO:0012505=IEA, GO:0031652=IEA, GO:0016021=IEA, GO:0015909=TAS, GO:0006659=IMP} adiponectin-mediated signaling pathway, cardiolipin biosynthetic process, cellular lipid metabolic process, fatty acid metabolic process, long-chain fatty acid transport, medium-chain fatty acid transport, negative regulation of phospholipid biosynthetic process, phosphatidic acid biosynthetic process, phosphatidylcholine biosynthetic process, phosphatidylethanolamine biosynthetic process, phosphatidylglycerol biosynthetic process, phosphatidylinositol biosynthetic process, phosphatidylserine biosynthetic process, positive regulation of heat generation, positive regulation of protein serine/threonine kinase activity, response to cold, response to insulin stimulus, small molecule metabolic process, transmembrane transport endomembrane system, endoplasmic reticulum, integral to membrane, plasma membrane catalytic activity, fatty acid transporter activity, nucleotide binding, protein homodimerization activity, very long-chain fatty acid-CoA ligase activity Human SLC27A2 Reactome UniProtKB {GO:0001676=PMID:22022213, GO:0006699=Reactome:REACT_11054, GO:0070251=PMID:10198260, GO:0005783=GO_REF:0000019, GO:0097089=PMID:10198260, GO:0030176=PMID:11980911, GO:0044281=Reactome:REACT_111217, GO:0005739=GO_REF:0000019, GO:0001561=Reactome:REACT_17003, GO:0050197=PMID:10198260, GO:0008206=Reactome:REACT_11040, GO:0031957=PMID:11980911, GO:0005779=PMID:10198260, GO:0044539=PMID:22022213, GO:0042760=GO_REF:0000019, GO:0005778=Reactome:REACT_17058, GO:0044255=Reactome:REACT_16957, GO:0005777=GO_REF:0000019, GO:0015245=GO_REF:0000019, GO:0006635=PMID:10198260, GO:0005102=PMID:20178365, GO:0005524=GO_REF:0000037, GO:0004467=PMID:22022213, GO:0005789=Reactome:REACT_10119, GO:0005788=PMID:10198260, GO:0019899=PMID:16781659} O14975 Very long-chain acyl-CoA synthetase protein 20130301 {GO:0001676=IDA, GO:0006699=TAS, GO:0070251=IDA, GO:0005783=IEA, GO:0097089=IDA, GO:0030176=IDA, GO:0044281=TAS, GO:0005739=IEA, GO:0001561=TAS, GO:0050197=IDA, GO:0008206=TAS, GO:0031957=IDA, GO:0005779=IDA, GO:0044539=IDA, GO:0042760=IEA, GO:0005778=TAS, GO:0044255=TAS, GO:0005777=IEA, GO:0015245=IEA, GO:0006635=IDA, GO:0005102=IPI, GO:0005524=IEA, GO:0004467=IDA, GO:0005789=TAS, GO:0005788=IDA, GO:0019899=IPI} bile acid biosynthetic process, bile acid metabolic process, cellular lipid metabolic process, fatty acid alpha-oxidation, fatty acid beta-oxidation, long-chain fatty acid import, long-chain fatty acid metabolic process, methyl-branched fatty acid metabolic process, small molecule metabolic process, very long-chain fatty acid catabolic process endoplasmic reticulum, endoplasmic reticulum lumen, endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane, integral to peroxisomal membrane, mitochondrion, peroxisomal membrane, peroxisome ATP binding, enzyme binding, fatty acid transporter activity, long-chain fatty acid-CoA ligase activity, phytanate-CoA ligase activity, pristanate-CoA ligase activity, receptor binding, very long-chain fatty acid-CoA ligase activity Human SLC27A3 UniProtKB UniProtKB {GO:0004321=GO_REF:0000019, GO:0031966=GO_REF:0000039, GO:0000166=GO_REF:0000037, GO:0016874=GO_REF:0000037, GO:0006631=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0003824=GO_REF:0000002} Q5K4L6 Long-chain fatty acid transport protein 3 protein 20130413 {GO:0004321=IEA, GO:0031966=IEA, GO:0000166=IEA, GO:0016874=IEA, GO:0006631=IEA, GO:0016021=IEA, GO:0003824=IEA} fatty acid metabolic process integral to membrane, mitochondrial membrane catalytic activity, fatty-acyl-CoA synthase activity, ligase activity, nucleotide binding Human UniProtKB-SubCell:SL-0171 SLC27A4 InterPro UniProtKB {GO:0006629=PMID:9878842, GO:0015245=PMID:9878842, GO:0001579=GO_REF:0000019, GO:0001676=PMID:22022213, GO:0005886=Reactome:REACT_23817, GO:0031526=GO_REF:0000019, GO:0003824=GO_REF:0000002, GO:0055085=Reactome:REACT_19118, GO:0004467=PMID:22022213, GO:0005902=GO_REF:0000019, GO:0000166=GO_REF:0000037, GO:0006810=PMID:9878842, GO:0005789=PMID:22022213, GO:0043588=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0015908=PMID:9878842, GO:0015909=Reactome:REACT_23892, GO:0031957=GO_REF:0000019, GO:0044539=PMID:22022213, GO:0042760=GO_REF:0000019} Q96G53 Long-chain fatty acid transport protein 4 protein 20130413 {GO:0006629=TAS, GO:0015245=TAS, GO:0001579=IEA, GO:0001676=IDA, GO:0005886=TAS, GO:0031526=IEA, GO:0003824=IEA, GO:0055085=TAS, GO:0004467=IDA, GO:0005902=IEA, GO:0000166=IEA, GO:0006810=TAS, GO:0005789=IDA, GO:0043588=IEA, GO:0016021=IEA, GO:0015908=TAS, GO:0015909=TAS, GO:0031957=IEA, GO:0044539=IDA, GO:0042760=IEA} fatty acid transport, lipid metabolic process, long-chain fatty acid import, long-chain fatty acid metabolic process, long-chain fatty acid transport, medium-chain fatty acid transport, skin development, transmembrane transport, transport, very long-chain fatty acid catabolic process brush border membrane, endoplasmic reticulum membrane, integral to membrane, microvillus, plasma membrane catalytic activity, fatty acid transporter activity, long-chain fatty acid-CoA ligase activity, nucleotide binding, very long-chain fatty acid-CoA ligase activity Human InterPro:IPR000873 SLC27A5 Reactome UniProtKB {GO:0015245=GO_REF:0000019, GO:0000038=PMID:10479480, GO:0005783=PMID:10479480, GO:0006699=Reactome:REACT_11054, GO:0030176=PMID:11980911, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0032403=GO_REF:0000019, GO:0015911=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0009925=GO_REF:0000019, GO:0047747=GO_REF:0000003, GO:0015721=Reactome:REACT_11042, GO:0046951=GO_REF:0000019, GO:0005789=Reactome:REACT_10087, GO:0008206=Reactome:REACT_11040, GO:0031957=PMID:11980911, GO:0006642=GO_REF:0000019} Q9Y2P5 Bile acyl-CoA synthetase protein 20130301 {GO:0015245=IEA, GO:0000038=IDA, GO:0005783=IDA, GO:0006699=TAS, GO:0030176=IDA, GO:0044281=TAS, GO:0003824=IEA, GO:0005524=IEA, GO:0032403=IEA, GO:0015911=IEA, GO:0043234=IEA, GO:0009925=IEA, GO:0047747=IEA, GO:0015721=TAS, GO:0046951=IEA, GO:0005789=TAS, GO:0008206=TAS, GO:0031957=IDA, GO:0006642=IEA} bile acid and bile salt transport, bile acid biosynthetic process, bile acid metabolic process, ketone body biosynthetic process, plasma membrane long-chain fatty acid transport, small molecule metabolic process, triglyceride mobilization, very long-chain fatty acid metabolic process basal plasma membrane, endoplasmic reticulum, endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane, protein complex ATP binding, catalytic activity, cholate-CoA ligase activity, fatty acid transporter activity, protein complex binding, very long-chain fatty acid-CoA ligase activity Human SLC27A6 GOC UniProtKB {GO:0042383=GO_REF:0000039, GO:0000038=PMID:10471116, GO:0001676=PMID:10471116, GO:0005886=Reactome:REACT_23817, GO:0000166=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0015909=Reactome:REACT_23892, GO:0031957=GO_REF:0000019, GO:0055085=Reactome:REACT_19118, GO:0004467=PMID:10471116} Q9Y2P4 Long-chain fatty acid transport protein 6 protein 20130413 {GO:0042383=IEA, GO:0000038=TAS, GO:0001676=TAS, GO:0005886=TAS, GO:0000166=IEA, GO:0016021=IEA, GO:0015909=TAS, GO:0031957=IEA, GO:0055085=TAS, GO:0004467=TAS} long-chain fatty acid metabolic process, long-chain fatty acid transport, transmembrane transport, very long-chain fatty acid metabolic process integral to membrane, plasma membrane, sarcolemma long-chain fatty acid-CoA ligase activity, nucleotide binding, very long-chain fatty acid-CoA ligase activity Human SLC28A1 Reactome UniProtKB {GO:0006139=PMID:9124315, GO:0005886=Reactome:REACT_714, GO:0016020=PMID:9124315, GO:0005887=PMID:9124315, GO:0005337=PMID:9124315, GO:0001882=GO_REF:0000002, GO:0005415=GO_REF:0000002, GO:0015858=PMID:9124315, GO:0055085=Reactome:REACT_19118} O00337 Sodium/nucleoside cotransporter 1 protein 20130301 {GO:0006139=TAS, GO:0005886=TAS, GO:0016020=TAS, GO:0005887=TAS, GO:0005337=TAS, GO:0001882=IEA, GO:0005415=IEA, GO:0015858=TAS, GO:0055085=TAS} nucleobase-containing compound metabolic process, nucleoside transport, transmembrane transport integral to plasma membrane, membrane, plasma membrane nucleoside binding, nucleoside transmembrane transporter activity, nucleoside:sodium symporter activity Human SLC28A2 Reactome UniProtKB {GO:0015860=PMID:9435697, GO:0006139=PMID:9435697, GO:0005886=Reactome:REACT_2011, GO:0016020=PMID:9435697, GO:0005887=PMID:9435697, GO:0001882=GO_REF:0000002, GO:0015211=PMID:9435697, GO:0005415=GO_REF:0000002, GO:0055085=Reactome:REACT_19118} O43868 Sodium/nucleoside cotransporter 2 protein 20130301 {GO:0015860=TAS, GO:0006139=TAS, GO:0005886=TAS, GO:0016020=TAS, GO:0005887=TAS, GO:0001882=IEA, GO:0015211=TAS, GO:0005415=IEA, GO:0055085=TAS} nucleobase-containing compound metabolic process, purine nucleoside transmembrane transport, transmembrane transport integral to plasma membrane, membrane, plasma membrane nucleoside binding, nucleoside:sodium symporter activity, purine nucleoside transmembrane transporter activity Human SLC28A3 Reactome UniProtKB {GO:0005886=Reactome:REACT_1504, GO:0016020=GO_REF:0000002, GO:0001882=GO_REF:0000002, GO:0015389=GO_REF:0000019, GO:0015864=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0015390=GO_REF:0000019, GO:0055085=Reactome:REACT_19118} Q9HAS3 Solute carrier family 28 member 3 protein 20130301 {GO:0005886=TAS, GO:0016020=IEA, GO:0001882=IEA, GO:0015389=IEA, GO:0015864=IEA, GO:0016021=IEA, GO:0015390=IEA, GO:0055085=TAS} pyrimidine nucleoside transport, transmembrane transport integral to membrane, membrane, plasma membrane nucleoside binding, purine-specific nucleoside:sodium symporter activity, pyrimidine- and adenine-specific:sodium symporter activity Human SLC29A1 Reactome UniProtKB {GO:0015862=GO_REF:0000019, GO:0005886=Reactome:REACT_1054, GO:0005337=GO_REF:0000019, GO:0060079=GO_REF:0000019, GO:0071456=GO_REF:0000019, GO:0030431=GO_REF:0000019, GO:0055085=Reactome:REACT_19118, GO:0016323=PMID:12527552, GO:0006139=PMID:8986748, GO:0016324=PMID:12527552, GO:0007595=GO_REF:0000019, GO:0016020=PMID:8986748, GO:0005887=PMID:8986748, GO:0015858=PMID:12527552, GO:0016021=GO_REF:0000002, GO:0071333=GO_REF:0000019} Q99808 Equilibrative nucleoside transporter 1 protein 20130301 {GO:0015862=IEA, GO:0005886=TAS, GO:0005337=IEA, GO:0060079=IEA, GO:0071456=IEA, GO:0030431=IEA, GO:0055085=TAS, GO:0016323=IDA, GO:0006139=TAS, GO:0016324=IDA, GO:0007595=IEA, GO:0016020=TAS, GO:0005887=TAS, GO:0015858=IDA, GO:0016021=IEA, GO:0071333=IEA} cellular response to glucose stimulus, cellular response to hypoxia, lactation, nucleobase-containing compound metabolic process, nucleoside transport, regulation of excitatory postsynaptic membrane potential, sleep, transmembrane transport, uridine transport apical plasma membrane, basolateral plasma membrane, integral to membrane, integral to plasma membrane, membrane, plasma membrane nucleoside transmembrane transporter activity Human SLC29A2 Reactome UniProtKB {GO:0016323=PMID:12527552, GO:0006139=PMID:9396714, GO:0031965=GO_REF:0000039, GO:0005886=Reactome:REACT_1268, GO:0008283=PMID:7639753, GO:0005887=PMID:7639753, GO:0005337=GO_REF:0000019, GO:0005730=PMID:7639753, GO:0015858=PMID:12527552, GO:0016021=GO_REF:0000002, GO:0055085=Reactome:REACT_19118} Q14542 Equilibrative nucleoside transporter 2 protein 20130301 {GO:0016323=IDA, GO:0006139=TAS, GO:0031965=IEA, GO:0005886=TAS, GO:0008283=TAS, GO:0005887=TAS, GO:0005337=IEA, GO:0005730=TAS, GO:0015858=IDA, GO:0016021=IEA, GO:0055085=TAS} cell proliferation, nucleobase-containing compound metabolic process, nucleoside transport, transmembrane transport basolateral plasma membrane, integral to membrane, integral to plasma membrane, nuclear membrane, nucleolus, plasma membrane nucleoside transmembrane transporter activity Human SLC2A1 IntAct UniProtKB {GO:0005886=Reactome:REACT_21415, GO:0006767=Reactome:REACT_11238, GO:0044281=Reactome:REACT_111217, GO:0042802=PMID:1429721, GO:0055056=GO_REF:0000019, GO:0008645=Reactome:REACT_9441, GO:0016323=GO_REF:0000019, GO:0042910=GO_REF:0000019, GO:0015758=Reactome:REACT_212, GO:0005911=GO_REF:0000019, GO:0022891=GO_REF:0000002, GO:0042149=GO_REF:0000019, GO:0019900=GO_REF:0000019, GO:0005355=PMID:9462754, GO:0042470=GO_REF:0000039, GO:0005975=Reactome:REACT_474, GO:0022857=GO_REF:0000002, GO:0030496=PMID:15166316, GO:0006970=GO_REF:0000019, GO:0055085=Reactome:REACT_19118, GO:0019852=Reactome:REACT_11202, GO:0001939=GO_REF:0000019, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0016020=PMID:3028891, GO:0006766=Reactome:REACT_11193, GO:0005901=GO_REF:0000019, GO:0033300=GO_REF:0000019, GO:0016021=GO_REF:0000037} P11166 Solute carrier family 2, facilitated glucose transporter member 1 protein 20130415 {GO:0005886=TAS, GO:0006767=TAS, GO:0044281=TAS, GO:0042802=IPI, GO:0055056=IEA, GO:0008645=TAS, GO:0016323=IEA, GO:0042910=IEA, GO:0015758=TAS, GO:0005911=IEA, GO:0022891=IEA, GO:0042149=IEA, GO:0019900=IEA, GO:0005355=TAS, GO:0042470=IEA, GO:0005975=TAS, GO:0022857=IEA, GO:0030496=IDA, GO:0006970=IEA, GO:0055085=TAS, GO:0019852=TAS, GO:0001939=IEA, GO:0006112=TAS, GO:0050796=TAS, GO:0016020=TAS, GO:0006766=TAS, GO:0005901=IEA, GO:0033300=IEA, GO:0016021=IEA} L-ascorbic acid metabolic process, carbohydrate metabolic process, cellular response to glucose starvation, energy reserve metabolic process, glucose transport, hexose transport, regulation of insulin secretion, response to osmotic stress, small molecule metabolic process, transmembrane transport, vitamin metabolic process, water-soluble vitamin metabolic process basolateral plasma membrane, caveola, cell-cell junction, female pronucleus, integral to membrane, melanosome, membrane, midbody, plasma membrane D-glucose transmembrane transporter activity, dehydroascorbic acid transporter activity, glucose transmembrane transporter activity, identical protein binding, kinase binding, substrate-specific transmembrane transporter activity, transmembrane transporter activity, xenobiotic transporter activity Human UniProtKB:P11166 SLC2A10 Reactome UniProtKB {GO:0048471=GO_REF:0000039, GO:0005886=Reactome:REACT_19350, GO:0015758=PMID:11247674, GO:0005351=PMID:11247674, GO:0016021=PMID:11247674, GO:0055085=Reactome:REACT_19118, GO:0012505=GO_REF:0000039} O95528 Solute carrier family 2, facilitated glucose transporter member 10 protein 20130301 {GO:0048471=IEA, GO:0005886=TAS, GO:0015758=NAS, GO:0005351=NAS, GO:0016021=NAS, GO:0055085=TAS, GO:0012505=IEA} glucose transport, transmembrane transport endomembrane system, integral to membrane, perinuclear region of cytoplasm, plasma membrane sugar:hydrogen symporter activity Human SLC2A12 Reactome UniProtKB {GO:0048471=GO_REF:0000039, GO:0005886=Reactome:REACT_19350, GO:0022891=GO_REF:0000002, GO:0008643=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0012505=GO_REF:0000039} Q8TD20 Solute carrier family 2, facilitated glucose transporter member 12 protein 20130301 {GO:0048471=IEA, GO:0005886=TAS, GO:0022891=IEA, GO:0008643=IEA, GO:0016021=IEA, GO:0055085=TAS, GO:0012505=IEA} carbohydrate transport, transmembrane transport endomembrane system, integral to membrane, perinuclear region of cytoplasm, plasma membrane substrate-specific transmembrane transporter activity Human SLC2A14 UniProtKB UniProtKB {GO:0022891=GO_REF:0000002, GO:0022857=GO_REF:0000002, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0005355=GO_REF:0000002} Q8TDB8 Solute carrier family 2, facilitated glucose transporter member 14 protein 20130413 {GO:0022891=IEA, GO:0022857=IEA, GO:0007275=IEA, GO:0007283=IEA, GO:0016021=IEA, GO:0030154=IEA, GO:0005355=IEA} cell differentiation, multicellular organismal development, spermatogenesis integral to membrane glucose transmembrane transporter activity, substrate-specific transmembrane transporter activity, transmembrane transporter activity Human UniProtKB-KW:KW-0221 SLC2A2 GOC UniProtKB {GO:0005886=Reactome:REACT_21415, GO:0005975=Reactome:REACT_474, GO:0044281=Reactome:REACT_111217, GO:0055085=Reactome:REACT_19118, GO:0015149=Reactome:REACT_9458, GO:0035428=Reactome:REACT_9458, GO:0055056=GO_REF:0000019, GO:0008645=Reactome:REACT_9441, GO:0005903=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0006112=Reactome:REACT_1505, GO:0015758=Reactome:REACT_212, GO:0016020=PMID:8027028, GO:0050796=Reactome:REACT_18325, GO:0005887=PMID:8027028, GO:0031018=Reactome:REACT_13819, GO:0022891=GO_REF:0000002, GO:0033300=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0005355=Reactome:REACT_21316} P11168 Solute carrier family 2, facilitated glucose transporter member 2 protein 20130413 {GO:0005886=TAS, GO:0005975=TAS, GO:0044281=TAS, GO:0055085=TAS, GO:0015149=TAS, GO:0035428=TAS, GO:0055056=IEA, GO:0008645=TAS, GO:0005903=IEA, GO:0005737=IEA, GO:0006112=TAS, GO:0015758=TAS, GO:0016020=TAS, GO:0050796=TAS, GO:0005887=TAS, GO:0031018=TAS, GO:0022891=IEA, GO:0033300=IEA, GO:0016021=IEA, GO:0005355=EXP} carbohydrate metabolic process, endocrine pancreas development, energy reserve metabolic process, glucose transport, hexose transmembrane transport, hexose transport, regulation of insulin secretion, small molecule metabolic process, transmembrane transport brush border, cytoplasm, integral to membrane, integral to plasma membrane, membrane, plasma membrane D-glucose transmembrane transporter activity, dehydroascorbic acid transporter activity, glucose transmembrane transporter activity, hexose transmembrane transporter activity, substrate-specific transmembrane transporter activity Human SLC2A3 Reactome UniProtKB {GO:0019852=Reactome:REACT_11202, GO:0015758=Reactome:REACT_212, GO:0005886=Reactome:REACT_19335, GO:0006766=Reactome:REACT_11193, GO:0005975=Reactome:REACT_474, GO:0022857=GO_REF:0000002, GO:0006767=Reactome:REACT_11238, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0005355=GO_REF:0000002, GO:0008645=Reactome:REACT_9441} P11169 Solute carrier family 2, facilitated glucose transporter member 3 protein 20091211 {GO:0019852=TAS, GO:0015758=TAS, GO:0005886=TAS, GO:0006766=TAS, GO:0005975=TAS, GO:0022857=IEA, GO:0006767=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0055085=TAS, GO:0005355=IEA, GO:0008645=TAS} L-ascorbic acid metabolic process, carbohydrate metabolic process, glucose transport, hexose transport, small molecule metabolic process, transmembrane transport, vitamin metabolic process, water-soluble vitamin metabolic process integral to membrane, plasma membrane glucose transmembrane transporter activity, transmembrane transporter activity Human SLC2A4 UniProtKB UniProtKB {GO:0010021=GO_REF:0000019, GO:0005515=PMID:11842083, GO:0048471=PMID:14562105, GO:0005886=Reactome:REACT_27264, GO:0045471=GO_REF:0000019, GO:0030136=PMID:19478182, GO:0044281=Reactome:REACT_111217, GO:0008645=Reactome:REACT_9441, GO:0055056=GO_REF:0000019, GO:0015758=Reactome:REACT_212, GO:0046323=PMID:11742412, GO:0030140=GO_REF:0000019, GO:0005355=GO_REF:0000002, GO:0070062=GO_REF:0000019, GO:0012506=PMID:14562105, GO:0032869=PMID:12556481, GO:0005975=Reactome:REACT_474, GO:0071470=GO_REF:0000019, GO:0005771=GO_REF:0000019, GO:0042593=PMID:17003346, GO:0055085=Reactome:REACT_19118, GO:0012505=GO_REF:0000024, GO:0042383=GO_REF:0000019, GO:0005905=GO_REF:0000019, GO:0016020=PMID:2649253, GO:0050873=GO_REF:0000019, GO:0005887=GO_REF:0000019, GO:0032593=GO_REF:0000024, GO:0016021=GO_REF:0000038, GO:0016044=Reactome:REACT_11123, GO:0009897=PMID:14562105} Q05BQ3 Solute carrier family 2, facilitated glucose transporter member 4 protein 20130413 {GO:0010021=IEA, GO:0005515=IPI, GO:0048471=IDA, GO:0005886=TAS, GO:0045471=IEA, GO:0030136=IDA, GO:0044281=TAS, GO:0008645=TAS, GO:0055056=IEA, GO:0015758=TAS, GO:0046323=NAS, GO:0030140=IEA, GO:0005355=IEA, GO:0070062=IEA, GO:0012506=IDA, GO:0032869=IDA, GO:0005975=TAS, GO:0071470=IEA, GO:0005771=IEA, GO:0042593=IDA, GO:0055085=TAS, GO:0012505=ISS, GO:0042383=IEA, GO:0005905=IEA, GO:0016020=TAS, GO:0050873=IEA, GO:0005887=IEA, GO:0032593=ISS, GO:0016021=IEA, GO:0016044=TAS, GO:0009897=IDA} amylopectin biosynthetic process, brown fat cell differentiation, carbohydrate metabolic process, cellular membrane organization, cellular response to insulin stimulus, cellular response to osmotic stress, glucose homeostasis, glucose import, glucose transport, hexose transport, response to ethanol, small molecule metabolic process, transmembrane transport clathrin-coated vesicle, coated pit, endomembrane system, external side of plasma membrane, extracellular vesicular exosome, insulin-responsive compartment, integral to membrane, integral to plasma membrane, membrane, multivesicular body, perinuclear region of cytoplasm, plasma membrane, sarcolemma, trans-Golgi network transport vesicle, vesicle membrane D-glucose transmembrane transporter activity, glucose transmembrane transporter activity, protein binding Human UniProtKB-KW:KW-0812 SLC2A4RG UniProtKB UniProtKB {GO:0006355=PMID:10825161, GO:0005737=GO_REF:0000039, GO:0003700=PMID:10825161, GO:0005634=PMID:10825161, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9NR83 SLC2A4 regulator protein 20010928 {GO:0006355=TAS, GO:0005737=IEA, GO:0003700=TAS, GO:0005634=NAS, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human SLC2A5 Reactome UniProtKB {GO:0015755=PMID:1634504, GO:0005886=Reactome:REACT_9449, GO:0015758=PMID:1695905, GO:0005975=Reactome:REACT_474, GO:0022891=GO_REF:0000002, GO:0005353=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0005355=GO_REF:0000019, GO:0008645=Reactome:REACT_9441} P22732 Solute carrier family 2, facilitated glucose transporter member 5 protein 20130301 {GO:0015755=TAS, GO:0005886=TAS, GO:0015758=TAS, GO:0005975=TAS, GO:0022891=IEA, GO:0005353=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0055085=TAS, GO:0005355=IEA, GO:0008645=TAS} carbohydrate metabolic process, fructose transport, glucose transport, hexose transport, small molecule metabolic process, transmembrane transport integral to membrane, plasma membrane fructose transmembrane transporter activity, glucose transmembrane transporter activity, substrate-specific transmembrane transporter activity Human SLC2A6 GOC UniProtKB {GO:0015758=PMID:10970791, GO:0005886=Reactome:REACT_19350, GO:0016020=PMID:10970791, GO:0022857=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0005355=PMID:10970791} Q9UGQ3 Solute carrier family 2, facilitated glucose transporter member 6 protein 20130413 {GO:0015758=NAS, GO:0005886=TAS, GO:0016020=NAS, GO:0022857=IEA, GO:0016021=IEA, GO:0055085=TAS, GO:0005355=NAS} glucose transport, transmembrane transport integral to membrane, membrane, plasma membrane glucose transmembrane transporter activity, transmembrane transporter activity Human SLC2A8 HPA UniProtKB {GO:0008286=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0005886=Reactome:REACT_19350, GO:0005975=PMID:10671487, GO:0022857=GO_REF:0000002, GO:0008643=GO_REF:0000038, GO:0055085=Reactome:REACT_19118, GO:0005536=GO_REF:0000019, GO:0008021=GO_REF:0000019, GO:0043231=GO_REF:0000052, GO:0015758=PMID:10671487, GO:0005887=GO_REF:0000019, GO:0022891=GO_REF:0000002, GO:0016021=GO_REF:0000002, GO:0007141=GO_REF:0000019, GO:0030659=GO_REF:0000039, GO:0005355=GO_REF:0000019} Q9NY64 Solute carrier family 2, facilitated glucose transporter member 8 protein 20081203 {GO:0008286=IEA, GO:0001666=IEA, GO:0005886=TAS, GO:0005975=TAS, GO:0022857=IEA, GO:0008643=IEA, GO:0055085=TAS, GO:0005536=IEA, GO:0008021=IEA, GO:0043231=IDA, GO:0015758=TAS, GO:0005887=IEA, GO:0022891=IEA, GO:0016021=IEA, GO:0007141=IEA, GO:0030659=IEA, GO:0005355=IEA} carbohydrate metabolic process, carbohydrate transport, glucose transport, insulin receptor signaling pathway, male meiosis I, response to hypoxia, transmembrane transport cytoplasmic vesicle membrane, integral to membrane, integral to plasma membrane, intracellular membrane-bounded organelle, plasma membrane, synaptic vesicle glucose binding, glucose transmembrane transporter activity, substrate-specific transmembrane transporter activity, transmembrane transporter activity Human SLC30A1 BHF-UCL UniProtKB {GO:0005886=PMID:17349999, GO:0071585=GO_REF:0000019, GO:0006874=GO_REF:0000024, GO:0030315=GO_REF:0000024, GO:0006882=GO_REF:0000024, GO:0071584=GO_REF:0000024, GO:0001701=GO_REF:0000019, GO:0055085=Reactome:REACT_19118, GO:0046929=GO_REF:0000024, GO:0090281=GO_REF:0000024, GO:0070509=GO_REF:0000019, GO:0005385=GO_REF:0000019, GO:0019855=GO_REF:0000024, GO:0070574=GO_REF:0000024, GO:0006829=GO_REF:0000024, GO:0016021=GO_REF:0000019} Q9Y6M5 Zinc transporter 1 protein 20100128 {GO:0005886=IDA, GO:0071585=IEA, GO:0006874=ISS, GO:0030315=ISS, GO:0006882=ISS, GO:0071584=ISS, GO:0001701=IEA, GO:0055085=TAS, GO:0046929=ISS, GO:0090281=ISS, GO:0070509=IEA, GO:0005385=IEA, GO:0019855=ISS, GO:0070574=ISS, GO:0006829=ISS, GO:0016021=IEA} cadmium ion transmembrane transport, calcium ion import, cellular calcium ion homeostasis, cellular zinc ion homeostasis, detoxification of cadmium ion, in utero embryonic development, negative regulation of calcium ion import, negative regulation of neurotransmitter secretion, negative regulation of zinc ion transmembrane import, transmembrane transport, zinc ion transport T-tubule, integral to membrane, plasma membrane calcium channel inhibitor activity, zinc ion transmembrane transporter activity Human SLC30A3 BHF-UCL UniProtKB {GO:0043005=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0061088=PMID:17349999, GO:0005770=PMID:17349999, GO:0008324=GO_REF:0000002, GO:0015633=PMID:8962159, GO:0055085=Reactome:REACT_19118, GO:0008021=PMID:8962159, GO:0005737=PMID:17349999, GO:0016020=PMID:8962159, GO:0005887=PMID:8962159, GO:0006810=PMID:8962159, GO:0030672=GO_REF:0000039, GO:0016021=GO_REF:0000002, GO:0051050=GO_REF:0000019, GO:0005768=PMID:8962159} Q99726 Zinc transporter 3 protein 20100505 {GO:0043005=ISS, GO:0030054=IEA, GO:0061088=IDA, GO:0005770=IDA, GO:0008324=IEA, GO:0015633=TAS, GO:0055085=TAS, GO:0008021=TAS, GO:0005737=IDA, GO:0016020=TAS, GO:0005887=TAS, GO:0006810=TAS, GO:0030672=IEA, GO:0016021=IEA, GO:0051050=IEA, GO:0005768=TAS} positive regulation of transport, regulation of sequestering of zinc ion, transmembrane transport, transport cell junction, cytoplasm, endosome, integral to membrane, integral to plasma membrane, late endosome, membrane, neuron projection, synaptic vesicle, synaptic vesicle membrane cation transmembrane transporter activity, zinc transporting ATPase activity Human SLC30A5 HPA UniProtKB {GO:0071577=PMID:11937503, GO:0005794=GO_REF:0000052, GO:0008324=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0006882=PMID:11937503, GO:0005634=GO_REF:0000052, GO:0055085=Reactome:REACT_19118, GO:0010043=PMID:11937503, GO:0016324=PMID:11937503, GO:0000139=Reactome:REACT_15499, GO:0005385=PMID:11937503, GO:0016020=PMID:11904301, GO:0005887=PMID:11937503, GO:0010155=PMID:11937503, GO:0006829=PMID:10330022, GO:0008270=PMID:11937503, GO:0016021=GO_REF:0000002, GO:0030141=PMID:10330022, GO:0044267=Reactome:REACT_17015, GO:0030667=Reactome:REACT_20545, GO:0006824=PMID:11937503} Q8TAD4 Zinc transporter 5 protein 20110516 {GO:0071577=IDA, GO:0005794=IDA, GO:0008324=IEA, GO:0005730=IDA, GO:0006882=IDA, GO:0005634=IDA, GO:0055085=TAS, GO:0010043=IDA, GO:0016324=IDA, GO:0000139=TAS, GO:0005385=IDA, GO:0016020=IDA, GO:0005887=TAS, GO:0010155=NAS, GO:0006829=IDA, GO:0008270=NAS, GO:0016021=IEA, GO:0030141=IDA, GO:0044267=TAS, GO:0030667=TAS, GO:0006824=IDA} cellular protein metabolic process, cellular zinc ion homeostasis, cobalt ion transport, regulation of proton transport, response to zinc ion, transmembrane transport, zinc ion transmembrane transport, zinc ion transport Golgi apparatus, Golgi membrane, apical plasma membrane, integral to membrane, integral to plasma membrane, membrane, nucleolus, nucleus, secretory granule, secretory granule membrane cation transmembrane transporter activity, zinc ion binding, zinc ion transmembrane transporter activity Human SLC30A6 BHF-UCL UniProtKB {GO:0005739=GO_REF:0000019, GO:0005794=PMID:17349999, GO:0000139=Reactome:REACT_20607, GO:0005385=GO_REF:0000019, GO:0008324=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0044267=Reactome:REACT_17015, GO:0006895=GO_REF:0000019} Q6NXT4 Zinc transporter 6 protein 20100128 {GO:0005739=IEA, GO:0005794=IDA, GO:0000139=TAS, GO:0005385=IEA, GO:0008324=IEA, GO:0016021=IEA, GO:0055085=TAS, GO:0044267=TAS, GO:0006895=IEA} Golgi to endosome transport, cellular protein metabolic process, transmembrane transport Golgi apparatus, Golgi membrane, integral to membrane, mitochondrion cation transmembrane transporter activity, zinc ion transmembrane transporter activity Human SLC30A7 HPA UniProtKB {GO:0005737=PMID:17349999, GO:0048471=GO_REF:0000019, GO:0005794=GO_REF:0000052, GO:0000139=Reactome:REACT_15499, GO:0032119=GO_REF:0000019, GO:0008324=GO_REF:0000002, GO:0016023=GO_REF:0000019, GO:0006829=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0031982=PMID:17349999, GO:0055085=Reactome:REACT_19118, GO:0044267=Reactome:REACT_17015} Q8NEW0 Zinc transporter 7 protein 20101115 {GO:0005737=IDA, GO:0048471=IEA, GO:0005794=IDA, GO:0000139=TAS, GO:0032119=IEA, GO:0008324=IEA, GO:0016023=IEA, GO:0006829=IEA, GO:0016021=IEA, GO:0031982=IDA, GO:0055085=TAS, GO:0044267=TAS} cellular protein metabolic process, sequestering of zinc ion, transmembrane transport, zinc ion transport Golgi apparatus, Golgi membrane, cytoplasm, cytoplasmic membrane-bounded vesicle, integral to membrane, perinuclear region of cytoplasm, vesicle cation transmembrane transporter activity Human SLC30A9 BHF-UCL UniProtKB {GO:0016922=GO_REF:0000019, GO:0003700=PMID:10409434, GO:0008324=GO_REF:0000002, GO:0005634=PMID:10409434, GO:0006351=GO_REF:0000037, GO:0030374=GO_REF:0000019, GO:0000166=GO_REF:0000002, GO:0003682=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0006829=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0006289=PMID:17349999, GO:0005856=PMID:10409434} Q6PML9 Zinc transporter 9 protein 20100128 {GO:0016922=IEA, GO:0003700=NAS, GO:0008324=IEA, GO:0005634=IDA, GO:0006351=IEA, GO:0030374=IEA, GO:0000166=IEA, GO:0003682=IEA, GO:0045944=IEA, GO:0006829=IEA, GO:0016021=IEA, GO:0006289=TAS, GO:0005856=IDA} nucleotide-excision repair, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent, zinc ion transport cytoskeleton, integral to membrane, nucleus cation transmembrane transporter activity, chromatin binding, ligand-dependent nuclear receptor binding, ligand-dependent nuclear receptor transcription coactivator activity, nucleotide binding, sequence-specific DNA binding transcription factor activity Human SLC31A1 InterPro UniProtKB {GO:0005886=Reactome:REACT_20667, GO:0005887=PMID:9207117, GO:0005375=GO_REF:0000002, GO:0016021=GO_REF:0000002, GO:0055085=Reactome:REACT_19118, GO:0006825=PMID:9207117} Q5T1M3 High affinity copper uptake protein 1 protein 20130413 {GO:0005886=TAS, GO:0005887=TAS, GO:0005375=IEA, GO:0016021=IEA, GO:0055085=TAS, GO:0006825=TAS} copper ion transport, transmembrane transport integral to membrane, integral to plasma membrane, plasma membrane copper ion transmembrane transporter activity Human InterPro:IPR007274 SLC31A2 PINC UniProtKB {GO:0005887=PMID:9207117, GO:0005375=GO_REF:0000002, GO:0006825=PMID:9207117} O15432 Probable low affinity copper uptake protein 2 protein 20030904 {GO:0005887=TAS, GO:0005375=IEA, GO:0006825=TAS} copper ion transport integral to plasma membrane copper ion transmembrane transporter activity Human SLC32A1 Reactome UniProtKB {GO:0043005=PMID:12115694, GO:0044306=PMID:12115694, GO:0005886=Reactome:REACT_23813, GO:0007568=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0015495=GO_REF:0000019, GO:0044292=GO_REF:0000019, GO:0060077=GO_REF:0000019, GO:0055085=Reactome:REACT_19118, GO:0007269=Reactome:REACT_13723, GO:0030425=PMID:12115694, GO:0044316=GO_REF:0000019, GO:0051286=GO_REF:0000019, GO:0015187=GO_REF:0000019, GO:0030672=Reactome:REACT_19142, GO:0061202=Reactome:REACT_23973, GO:0016021=GO_REF:0000037, GO:0006811=Reactome:REACT_19397} Q9H598 Vesicular inhibitory amino acid transporter protein 20120214 {GO:0043005=IDA, GO:0044306=IDA, GO:0005886=TAS, GO:0007568=IEA, GO:0007268=TAS, GO:0015495=IEA, GO:0044292=IEA, GO:0060077=IEA, GO:0055085=TAS, GO:0007269=TAS, GO:0030425=IDA, GO:0044316=IEA, GO:0051286=IEA, GO:0015187=IEA, GO:0030672=TAS, GO:0061202=TAS, GO:0016021=IEA, GO:0006811=TAS} aging, ion transport, neurotransmitter secretion, synaptic transmission, transmembrane transport cell tip, clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane, cone cell pedicle, dendrite, dendrite terminus, inhibitory synapse, integral to membrane, neuron projection, neuron projection terminus, plasma membrane, synaptic vesicle membrane gamma-aminobutyric acid:hydrogen symporter activity, glycine transmembrane transporter activity Human SLC33A1 GOC UniProtKB {GO:0008219=GO_REF:0000037, GO:0008521=GO_REF:0000002, GO:0000139=Reactome:REACT_22226, GO:0016020=PMID:9096318, GO:0005887=PMID:9096318, GO:0006810=PMID:9096318, GO:0005789=GO_REF:0000039, GO:0015876=PMID:9096318, GO:0016021=GO_REF:0000002, GO:0055085=Reactome:REACT_19118} O00400 Acetyl-coenzyme A transporter 1 protein 20130413 {GO:0008219=IEA, GO:0008521=IEA, GO:0000139=TAS, GO:0016020=TAS, GO:0005887=TAS, GO:0006810=TAS, GO:0005789=IEA, GO:0015876=TAS, GO:0016021=IEA, GO:0055085=TAS} acetyl-CoA transport, cell death, transmembrane transport, transport Golgi membrane, endoplasmic reticulum membrane, integral to membrane, integral to plasma membrane, membrane acetyl-CoA transporter activity Human SLC34A1 Reactome UniProtKB {GO:0005515=PMID:22506049, GO:0010288=PMID:8898024, GO:0005886=Reactome:REACT_19133, GO:0055062=PMID:8327470, GO:0031526=GO_REF:0000024, GO:0055085=Reactome:REACT_19118, GO:0016323=GO_REF:0000019, GO:0015321=PMID:8327470, GO:0046849=GO_REF:0000019, GO:0005887=PMID:8327470, GO:0032026=GO_REF:0000019, GO:0006817=PMID:8327470, GO:0006814=GO_REF:0000037, GO:0046689=PMID:8898024, GO:0046686=PMID:8898024, GO:0006811=Reactome:REACT_19397, GO:0015293=GO_REF:0000037} Q06495 Sodium-dependent phosphate transport protein 2A protein 20130301 {GO:0005515=IPI, GO:0010288=IDA, GO:0005886=TAS, GO:0055062=IDA, GO:0031526=ISS, GO:0055085=TAS, GO:0016323=IEA, GO:0015321=IDA, GO:0046849=IEA, GO:0005887=NAS, GO:0032026=IEA, GO:0006817=IDA, GO:0006814=IEA, GO:0046689=IDA, GO:0046686=IDA, GO:0006811=TAS, GO:0015293=IEA} bone remodeling, ion transport, phosphate ion homeostasis, phosphate ion transport, response to cadmium ion, response to lead ion, response to magnesium ion, response to mercury ion, sodium ion transport, transmembrane transport basolateral plasma membrane, brush border membrane, integral to plasma membrane, plasma membrane protein binding, sodium-dependent phosphate transmembrane transporter activity, symporter activity Human SLC34A3 Reactome UniProtKB {GO:0005903=GO_REF:0000019, GO:0016324=PMID:11880379, GO:0005436=PMID:11880379, GO:0015321=PMID:11880379, GO:0005886=Reactome:REACT_19211, GO:0030643=PMID:16358214, GO:0006817=PMID:11880379, GO:0016021=GO_REF:0000037, GO:0006814=PMID:11880379, GO:0055085=Reactome:REACT_19118, GO:0006811=Reactome:REACT_19397} Q8N130 Sodium-dependent phosphate transport protein 2C protein 20130301 {GO:0005903=IEA, GO:0016324=ISS, GO:0005436=IDA, GO:0015321=IDA, GO:0005886=TAS, GO:0030643=IDA, GO:0006817=IDA, GO:0016021=IEA, GO:0006814=IDA, GO:0055085=TAS, GO:0006811=TAS} cellular phosphate ion homeostasis, ion transport, phosphate ion transport, sodium ion transport, transmembrane transport apical plasma membrane, brush border, integral to membrane, plasma membrane sodium-dependent phosphate transmembrane transporter activity, sodium:phosphate symporter activity Human SLC35A2 HPA UniProtKB {GO:0005794=GO_REF:0000052, GO:0015780=GO_REF:0000002, GO:0015785=PMID:9010752, GO:0005338=GO_REF:0000002, GO:0000139=Reactome:REACT_22299, GO:0005634=GO_REF:0000052, GO:0005351=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0006012=PMID:9010752, GO:0005459=GO_REF:0000019, GO:0055085=Reactome:REACT_19118} P78381 UDP-galactose translocator protein 20101115 {GO:0005794=IDA, GO:0015780=IEA, GO:0015785=TAS, GO:0005338=IEA, GO:0000139=TAS, GO:0005634=IDA, GO:0005351=IEA, GO:0016021=IEA, GO:0006012=TAS, GO:0005459=IEA, GO:0055085=TAS} UDP-galactose transport, galactose metabolic process, nucleotide-sugar transport, transmembrane transport Golgi apparatus, Golgi membrane, integral to membrane, nucleus UDP-galactose transmembrane transporter activity, nucleotide-sugar transmembrane transporter activity, sugar:hydrogen symporter activity Human SLC35A3 Reactome UniProtKB {GO:0005794=PMID:10393322, GO:0015780=GO_REF:0000002, GO:0005338=GO_REF:0000002, GO:0000139=Reactome:REACT_22160, GO:0005462=PMID:10393322, GO:0005351=GO_REF:0000002, GO:0006047=PMID:10393322, GO:0016021=GO_REF:0000037, GO:0015788=PMID:10393322, GO:0055085=Reactome:REACT_19118} Q9Y2D2 UDP-N-acetylglucosamine transporter protein 20130301 {GO:0005794=TAS, GO:0015780=IEA, GO:0005338=IEA, GO:0000139=TAS, GO:0005462=TAS, GO:0005351=IEA, GO:0006047=TAS, GO:0016021=IEA, GO:0015788=TAS, GO:0055085=TAS} UDP-N-acetylglucosamine metabolic process, UDP-N-acetylglucosamine transport, nucleotide-sugar transport, transmembrane transport Golgi apparatus, Golgi membrane, integral to membrane UDP-N-acetylglucosamine transmembrane transporter activity, nucleotide-sugar transmembrane transporter activity, sugar:hydrogen symporter activity Human SLC35A5 UniProtKB UniProtKB {GO:0015780=GO_REF:0000002, GO:0005338=GO_REF:0000002, GO:0000139=GO_REF:0000002, GO:0005351=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q9BS91 Probable UDP-sugar transporter protein SLC35A5 protein 20130413 {GO:0015780=IEA, GO:0005338=IEA, GO:0000139=IEA, GO:0005351=IEA, GO:0016021=IEA} nucleotide-sugar transport Golgi membrane, integral to membrane nucleotide-sugar transmembrane transporter activity, sugar:hydrogen symporter activity Human UniProtKB-KW:KW-0812 SLC35B1 GOC UniProtKB {GO:0072334=PMID:9010752, GO:0006810=PMID:9010752, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0005459=PMID:9010752, GO:0055085=GO_REF:0000002, GO:0043231=PMID:9010752} P78383 Solute carrier family 35 member B1 protein 20130413 {GO:0072334=TAS, GO:0006810=TAS, GO:0005789=IEA, GO:0016021=IEA, GO:0005459=TAS, GO:0055085=IEA, GO:0043231=TAS} UDP-galactose transmembrane transport, transmembrane transport, transport endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle UDP-galactose transmembrane transporter activity Human SLC35B2 GOC UniProtKB {GO:0007165=PMID:12761501, GO:0005794=PMID:12716889, GO:0000139=Reactome:REACT_22255, GO:0016020=PMID:12716889, GO:0046964=PMID:12716889, GO:0046963=PMID:12716889, GO:0004871=PMID:12761501, GO:0016021=PMID:12716889, GO:0043123=PMID:12761501, GO:0055085=Reactome:REACT_19118} Q8TB61 Adenosine 3'-phospho 5'-phosphosulfate transporter 1 protein 20130413 {GO:0007165=IMP, GO:0005794=IDA, GO:0000139=TAS, GO:0016020=IDA, GO:0046964=IDA, GO:0046963=IDA, GO:0004871=IMP, GO:0016021=NAS, GO:0043123=IMP, GO:0055085=TAS} 3'-phosphoadenosine 5'-phosphosulfate transport, positive regulation of I-kappaB kinase/NF-kappaB cascade, signal transduction, transmembrane transport Golgi apparatus, Golgi membrane, integral to membrane, membrane 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity, signal transducer activity Human SLC35C2 MGI UniProtKB {GO:0005801=PMID:20837470, GO:0005793=PMID:20837470, GO:0006810=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q9NQQ7 Solute carrier family 35 member C2 protein 20130124 {GO:0005801=IDA, GO:0005793=IDA, GO:0006810=IEA, GO:0016021=IEA} transport cis-Golgi network, endoplasmic reticulum-Golgi intermediate compartment, integral to membrane Human SLC35D1 GOC UniProtKB {GO:0006805=Reactome:REACT_13433, GO:0048706=GO_REF:0000019, GO:0008643=GO_REF:0000037, GO:0030176=GO_REF:0000029, GO:0006065=Reactome:REACT_6737, GO:0044281=Reactome:REACT_111217, GO:0015787=Reactome:REACT_6892, GO:0055085=Reactome:REACT_19118, GO:0015789=GO_REF:0000029, GO:0030206=GO_REF:0000029, GO:0005461=Reactome:REACT_6892, GO:0005463=GO_REF:0000029, GO:0005789=Reactome:REACT_6892, GO:0016021=GO_REF:0000038} Q9NTN3 UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter protein 20130413 {GO:0006805=TAS, GO:0048706=IEA, GO:0008643=IEA, GO:0030176=NAS, GO:0006065=TAS, GO:0044281=TAS, GO:0015787=TAS, GO:0055085=TAS, GO:0015789=NAS, GO:0030206=NAS, GO:0005461=TAS, GO:0005463=NAS, GO:0005789=TAS, GO:0016021=IEA} UDP-N-acetylgalactosamine transport, UDP-glucuronate biosynthetic process, UDP-glucuronic acid transport, carbohydrate transport, chondroitin sulfate biosynthetic process, embryonic skeletal system development, small molecule metabolic process, transmembrane transport, xenobiotic metabolic process endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane, integral to membrane UDP-N-acetylgalactosamine transmembrane transporter activity, UDP-glucuronic acid transmembrane transporter activity Human SLC35E1 UniProtKB UniProtKB {GO:0006810=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q96K37 Solute carrier family 35 member E1 protein 20130413 {GO:0006810=IEA, GO:0016021=IEA} transport integral to membrane Human UniProtKB-KW:KW-0812 SLC35E2 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} P0CK97 Solute carrier family 35 member E2 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 SLC35E4 UniProtKB UniProtKB {GO:0016020=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q6ICL7 Solute carrier family 35 member E4 protein 20130413 {GO:0016020=IEA, GO:0016021=IEA} integral to membrane, membrane Human UniProtKB-KW:KW-0812 SLC35F2 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0006810=GO_REF:0000037, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} Q8IXU6 Solute carrier family 35 member F2 protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0006810=IEA, GO:0005575=ND, GO:0016021=IEA} biological_process, transport cellular_component, integral to membrane molecular_function Human SLC35F3 UniProtKB UniProtKB {GO:0006810=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q8IY50 Solute carrier family 35 member F3 protein 20130413 {GO:0006810=IEA, GO:0016021=IEA} transport integral to membrane Human UniProtKB-KW:KW-0812 SLC35F5 UniProtKB UniProtKB {GO:0016020=GO_REF:0000002, GO:0006810=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q8WV83 Solute carrier family 35 member F5 protein 20130413 {GO:0016020=IEA, GO:0006810=IEA, GO:0016021=IEA} transport integral to membrane, membrane Human UniProtKB-KW:KW-0812 SLC35G1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q2M3R5 Solute carrier family 35 member G1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 SLC37A1 UniProtKB UniProtKB {GO:0005215=GO_REF:0000002, GO:0008643=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0055085=GO_REF:0000002} P57057 Glycerol-3-phosphate transporter protein 20130413 {GO:0005215=IEA, GO:0008643=IEA, GO:0016021=IEA, GO:0055085=IEA} carbohydrate transport, transmembrane transport integral to membrane transporter activity Human UniProtKB-KW:KW-0812 SLC37A3 UniProtKB UniProtKB {GO:0005215=GO_REF:0000002, GO:0008643=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0055085=GO_REF:0000002} Q8NCC5 Sugar phosphate exchanger 3 protein 20130413 {GO:0005215=IEA, GO:0008643=IEA, GO:0016021=IEA, GO:0055085=IEA} carbohydrate transport, transmembrane transport integral to membrane transporter activity Human UniProtKB-KW:KW-0812 SLC37A4 Reactome UniProtKB {GO:0005215=PMID:9428641, GO:0005783=PMID:212064, GO:0005975=Reactome:REACT_474, GO:0015760=PMID:12560945, GO:0044281=Reactome:REACT_111217, GO:0055085=Reactome:REACT_19118, GO:0008645=Reactome:REACT_9441, GO:0015152=PMID:12560945, GO:0015758=Reactome:REACT_212, GO:0006810=PMID:9428641, GO:0005789=Reactome:REACT_11151, GO:0006006=PMID:9428641, GO:0016021=PMID:9428641} O43826 Glucose-6-phosphate translocase protein 20130301 {GO:0005215=NAS, GO:0005783=NAS, GO:0005975=TAS, GO:0015760=IMP, GO:0044281=TAS, GO:0055085=TAS, GO:0008645=TAS, GO:0015152=IMP, GO:0015758=TAS, GO:0006810=NAS, GO:0005789=TAS, GO:0006006=NAS, GO:0016021=NAS} carbohydrate metabolic process, glucose metabolic process, glucose transport, glucose-6-phosphate transport, hexose transport, small molecule metabolic process, transmembrane transport, transport endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane glucose-6-phosphate transmembrane transporter activity, transporter activity Human SLC38A1 Reactome UniProtKB {GO:0015804=PMID:10891391, GO:0030424=GO_REF:0000019, GO:0005886=Reactome:REACT_13773, GO:0001504=Reactome:REACT_13594, GO:0005283=PMID:10891391, GO:0006865=Reactome:REACT_13796, GO:0015175=PMID:10891391, GO:0007268=Reactome:REACT_13685, GO:0015186=GO_REF:0000019, GO:0016021=PMID:10891391, GO:0055085=Reactome:REACT_19118, GO:0006811=Reactome:REACT_19397} Q9H2H9 Sodium-coupled neutral amino acid transporter 1 protein 20130301 {GO:0015804=NAS, GO:0030424=IEA, GO:0005886=TAS, GO:0001504=TAS, GO:0005283=NAS, GO:0006865=TAS, GO:0015175=NAS, GO:0007268=TAS, GO:0015186=IEA, GO:0016021=NAS, GO:0055085=TAS, GO:0006811=TAS} amino acid transport, ion transport, neurotransmitter uptake, neutral amino acid transport, synaptic transmission, transmembrane transport axon, integral to membrane, plasma membrane L-glutamine transmembrane transporter activity, neutral amino acid transmembrane transporter activity, sodium:amino acid symporter activity Human SLC38A10 UniProtKB UniProtKB {GO:0006865=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0006814=GO_REF:0000037} Q9HBR0 Putative sodium-coupled neutral amino acid transporter 10 protein 20130413 {GO:0006865=IEA, GO:0016021=IEA, GO:0006814=IEA} amino acid transport, sodium ion transport integral to membrane Human UniProtKB-KW:KW-0812 SLC38A2 Reactome UniProtKB {GO:0005886=Reactome:REACT_13763, GO:0015171=GO_REF:0000019, GO:0006865=Reactome:REACT_13796, GO:0007268=Reactome:REACT_13685, GO:0016021=GO_REF:0000037, GO:0006814=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0014047=Reactome:REACT_12591, GO:0007269=Reactome:REACT_13723, GO:0006811=Reactome:REACT_19397, GO:0015293=GO_REF:0000037} Q96QD8 Sodium-coupled neutral amino acid transporter 2 protein 20130301 {GO:0005886=TAS, GO:0015171=IEA, GO:0006865=TAS, GO:0007268=TAS, GO:0016021=IEA, GO:0006814=IEA, GO:0055085=TAS, GO:0014047=TAS, GO:0007269=TAS, GO:0006811=TAS, GO:0015293=IEA} amino acid transport, glutamate secretion, ion transport, neurotransmitter secretion, sodium ion transport, synaptic transmission, transmembrane transport integral to membrane, plasma membrane amino acid transmembrane transporter activity, symporter activity Human SLC38A3 Reactome UniProtKB {GO:0005290=PMID:10823827, GO:0005886=Reactome:REACT_13659, GO:0006865=Reactome:REACT_13796, GO:0055085=Reactome:REACT_19118, GO:0015180=PMID:10823827, GO:0015297=GO_REF:0000037, GO:0005887=GO_REF:0000024, GO:0006867=PMID:10823827, GO:0006868=PMID:10823827, GO:0015182=PMID:10823827, GO:0015186=PMID:10823827, GO:0006814=GO_REF:0000037, GO:0015808=PMID:10823827, GO:0015817=PMID:10823827, GO:0006811=Reactome:REACT_19397, GO:0015293=GO_REF:0000037} Q99624 Sodium-coupled neutral amino acid transporter 3 protein 20130301 {GO:0005290=IDA, GO:0005886=TAS, GO:0006865=TAS, GO:0055085=TAS, GO:0015180=IDA, GO:0015297=IEA, GO:0005887=ISS, GO:0006867=IDA, GO:0006868=IDA, GO:0015182=IDA, GO:0015186=IDA, GO:0006814=IEA, GO:0015808=IDA, GO:0015817=IDA, GO:0006811=TAS, GO:0015293=IEA} L-alanine transport, amino acid transport, asparagine transport, glutamine transport, histidine transport, ion transport, sodium ion transport, transmembrane transport integral to plasma membrane, plasma membrane L-alanine transmembrane transporter activity, L-asparagine transmembrane transporter activity, L-glutamine transmembrane transporter activity, L-histidine transmembrane transporter activity, antiporter activity, symporter activity Human SLC38A5 Reactome UniProtKB {GO:0005886=Reactome:REACT_13564, GO:0006865=Reactome:REACT_13796, GO:0015187=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0006811=Reactome:REACT_19397} Q8WUX1 Sodium-coupled neutral amino acid transporter 5 protein 20130301 {GO:0005886=TAS, GO:0006865=TAS, GO:0015187=IEA, GO:0016021=IEA, GO:0055085=TAS, GO:0006811=TAS} amino acid transport, ion transport, transmembrane transport integral to membrane, plasma membrane glycine transmembrane transporter activity Human SLC38A6 UniProtKB UniProtKB {GO:0006865=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0006814=GO_REF:0000037} Q8IZM9 Probable sodium-coupled neutral amino acid transporter 6 protein 20130413 {GO:0006865=IEA, GO:0016021=IEA, GO:0006814=IEA} amino acid transport, sodium ion transport integral to membrane Human UniProtKB-KW:KW-0812 SLC39A1 Reactome UniProtKB {GO:0071577=PMID:12888280, GO:0005886=Reactome:REACT_20673, GO:0005385=GO_REF:0000019, GO:0016020=PMID:10610721, GO:0022890=PMID:10610721, GO:0046873=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0005102=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0006812=PMID:10610721} Q9NY26 Zinc transporter ZIP1 protein 20130301 {GO:0071577=IMP, GO:0005886=TAS, GO:0005385=IEA, GO:0016020=TAS, GO:0022890=TAS, GO:0046873=IEA, GO:0005789=IEA, GO:0005102=IEA, GO:0016021=IEA, GO:0055085=TAS, GO:0006812=TAS} cation transport, transmembrane transport, zinc ion transmembrane transport endoplasmic reticulum membrane, integral to membrane, membrane, plasma membrane inorganic cation transmembrane transporter activity, metal ion transmembrane transporter activity, receptor binding, zinc ion transmembrane transporter activity Human SLC39A10 Reactome UniProtKB {GO:0016020=GO_REF:0000002, GO:0046873=GO_REF:0000002, GO:0006829=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_19118} Q9ULF5 Zinc transporter ZIP10 protein 20130301 {GO:0016020=IEA, GO:0046873=IEA, GO:0006829=IEA, GO:0016021=IEA, GO:0055085=TAS} transmembrane transport, zinc ion transport integral to membrane, membrane metal ion transmembrane transporter activity Human SLC39A11 UniProtKB UniProtKB {GO:0016020=GO_REF:0000002, GO:0046873=GO_REF:0000002, GO:0006829=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q8N1S5 Zinc transporter ZIP11 protein 20130413 {GO:0016020=IEA, GO:0046873=IEA, GO:0006829=IEA, GO:0016021=IEA} zinc ion transport integral to membrane, membrane metal ion transmembrane transporter activity Human UniProtKB-KW:KW-0812 SLC39A14 BHF-UCL UniProtKB {GO:0071577=PMID:21917916, GO:0071578=PMID:15642354, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005783=GO_REF:0000052, GO:0006882=PMID:15642354, GO:0015093=GO_REF:0000019, GO:0055085=Reactome:REACT_19118, GO:0030027=GO_REF:0000039, GO:0005385=PMID:15642354, GO:0005887=PMID:15642354, GO:0046873=GO_REF:0000002, GO:0016021=PMID:21917916} Q15043 Zinc transporter ZIP14 protein 20111123 {GO:0071577=IDA, GO:0071578=IDA, GO:0005794=IDA, GO:0005886=IDA, GO:0005783=IDA, GO:0006882=IDA, GO:0015093=IEA, GO:0055085=TAS, GO:0030027=IEA, GO:0005385=IDA, GO:0005887=IDA, GO:0046873=IEA, GO:0016021=IDA} cellular zinc ion homeostasis, transmembrane transport, zinc ion transmembrane import, zinc ion transmembrane transport Golgi apparatus, endoplasmic reticulum, integral to membrane, integral to plasma membrane, lamellipodium, plasma membrane ferrous iron transmembrane transporter activity, metal ion transmembrane transporter activity, zinc ion transmembrane transporter activity Human SLC39A2 Reactome UniProtKB {GO:0005385=PMID:20148757, GO:0005886=Reactome:REACT_20673, GO:0016020=GO_REF:0000002, GO:0005887=PMID:10681536, GO:0046873=GO_REF:0000002, GO:0016023=PMID:14612438, GO:0006829=PMID:10681536, GO:0055085=Reactome:REACT_19118} Q9NP94 Zinc transporter ZIP2 protein 20130301 {GO:0005385=IMP, GO:0005886=TAS, GO:0016020=IEA, GO:0005887=TAS, GO:0046873=IEA, GO:0016023=IDA, GO:0006829=TAS, GO:0055085=TAS} transmembrane transport, zinc ion transport cytoplasmic membrane-bounded vesicle, integral to plasma membrane, membrane, plasma membrane metal ion transmembrane transporter activity, zinc ion transmembrane transporter activity Human SLC39A3 Reactome UniProtKB {GO:0005886=Reactome:REACT_20673, GO:0005385=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0046873=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_19118} Q9BRY0 Zinc transporter ZIP3 protein 20130301 {GO:0005886=TAS, GO:0005385=IEA, GO:0016020=IEA, GO:0046873=IEA, GO:0016021=IEA, GO:0055085=TAS} transmembrane transport integral to membrane, membrane, plasma membrane metal ion transmembrane transporter activity, zinc ion transmembrane transporter activity Human SLC39A4 Reactome UniProtKB {GO:0016324=GO_REF:0000019, GO:0005886=Reactome:REACT_20673, GO:0005385=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0046873=GO_REF:0000002, GO:0016023=PMID:14612438, GO:0006882=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0034224=GO_REF:0000019, GO:0055085=Reactome:REACT_19118, GO:0055038=GO_REF:0000039} Q6P5W5 Zinc transporter ZIP4 protein 20130301 {GO:0016324=IEA, GO:0005886=TAS, GO:0005385=IEA, GO:0016020=IEA, GO:0046873=IEA, GO:0016023=IDA, GO:0006882=IEA, GO:0016021=IEA, GO:0034224=IEA, GO:0055085=TAS, GO:0055038=IEA} cellular response to zinc ion starvation, cellular zinc ion homeostasis, transmembrane transport apical plasma membrane, cytoplasmic membrane-bounded vesicle, integral to membrane, membrane, plasma membrane, recycling endosome membrane metal ion transmembrane transporter activity, zinc ion transmembrane transporter activity Human SLC39A6 BHF-UCL UniProtKB {GO:0071577=PMID:12839489, GO:0071578=PMID:15642354, GO:0005385=PMID:15642354, GO:0005886=Reactome:REACT_20648, GO:0031258=PMID:12839489, GO:0016020=GO_REF:0000002, GO:0005887=PMID:15642354, GO:0005783=GO_REF:0000019, GO:0046873=GO_REF:0000002, GO:0006882=PMID:15642354, GO:0055085=Reactome:REACT_19118} Q13433 Zinc transporter ZIP6 protein 20111123 {GO:0071577=IMP, GO:0071578=IDA, GO:0005385=IDA, GO:0005886=TAS, GO:0031258=IDA, GO:0016020=IEA, GO:0005887=IDA, GO:0005783=IEA, GO:0046873=IEA, GO:0006882=IDA, GO:0055085=TAS} cellular zinc ion homeostasis, transmembrane transport, zinc ion transmembrane import, zinc ion transmembrane transport endoplasmic reticulum, integral to plasma membrane, lamellipodium membrane, membrane, plasma membrane metal ion transmembrane transporter activity, zinc ion transmembrane transporter activity Human SLC39A7 Reactome UniProtKB {GO:0016020=PMID:8812499, GO:0046873=GO_REF:0000002, GO:0005789=Reactome:REACT_20575, GO:0006829=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_19118} Q92504 Zinc transporter SLC39A7 protein 20130301 {GO:0016020=TAS, GO:0046873=IEA, GO:0005789=TAS, GO:0006829=IEA, GO:0016021=IEA, GO:0055085=TAS} transmembrane transport, zinc ion transport endoplasmic reticulum membrane, integral to membrane, membrane metal ion transmembrane transporter activity Human SLC3A1 InterPro UniProtKB {GO:0005774=GO_REF:0000019, GO:0006520=PMID:8054986, GO:0005886=Reactome:REACT_15542, GO:0046982=GO_REF:0000019, GO:0005975=GO_REF:0000002, GO:0043169=GO_REF:0000002, GO:0005743=GO_REF:0000019, GO:0006865=Reactome:REACT_13796, GO:0003824=GO_REF:0000002, GO:0003333=PMID:10799513, GO:0055085=Reactome:REACT_19118, GO:0015802=PMID:8054986, GO:0015184=PMID:8054986, GO:0016020=PMID:8054986, GO:0015171=PMID:10799513, GO:0005887=GO_REF:0000019, GO:0015811=PMID:8054986, GO:0015174=PMID:8054986, GO:0006811=Reactome:REACT_19397} Q4J6B8 Neutral and basic amino acid transport protein rBAT protein 20130413 {GO:0005774=IEA, GO:0006520=TAS, GO:0005886=TAS, GO:0046982=IEA, GO:0005975=IEA, GO:0043169=IEA, GO:0005743=IEA, GO:0006865=TAS, GO:0003824=IEA, GO:0003333=TAS, GO:0055085=TAS, GO:0015802=TAS, GO:0015184=TAS, GO:0016020=TAS, GO:0015171=TAS, GO:0005887=IEA, GO:0015811=TAS, GO:0015174=TAS, GO:0006811=TAS} L-cystine transport, amino acid transmembrane transport, amino acid transport, basic amino acid transport, carbohydrate metabolic process, cellular amino acid metabolic process, ion transport, transmembrane transport integral to plasma membrane, membrane, mitochondrial inner membrane, plasma membrane, vacuolar membrane L-cystine transmembrane transporter activity, amino acid transmembrane transporter activity, basic amino acid transmembrane transporter activity, catalytic activity, cation binding, protein heterodimerization activity Human InterPro:IPR006047|InterPro:IPR006589 SLC3A2 Reactome UniProtKB {GO:0005515=PMID:10631289, GO:0042470=GO_REF:0000039, GO:0005886=Reactome:REACT_16988, GO:0009986=PMID:12493773, GO:0005975=GO_REF:0000002, GO:0043169=GO_REF:0000002, GO:0006865=Reactome:REACT_13796, GO:0050900=Reactome:REACT_12051, GO:0003824=GO_REF:0000002, GO:0055085=Reactome:REACT_19118, GO:0005432=PMID:10673541, GO:0016324=GO_REF:0000039, GO:0015827=GO_REF:0000024, GO:0007596=Reactome:REACT_604, GO:0015175=GO_REF:0000024, GO:0016049=PMID:3476959, GO:0006816=PMID:3036867, GO:0016021=PMID:3476959, GO:0060356=GO_REF:0000024, GO:0006811=Reactome:REACT_19397} P08195 4F2 cell-surface antigen heavy chain protein 20130213 {GO:0005515=IPI, GO:0042470=IEA, GO:0005886=TAS, GO:0009986=IDA, GO:0005975=IEA, GO:0043169=IEA, GO:0006865=TAS, GO:0050900=TAS, GO:0003824=IEA, GO:0055085=TAS, GO:0005432=TAS, GO:0016324=IEA, GO:0015827=ISS, GO:0007596=TAS, GO:0015175=ISS, GO:0016049=NAS, GO:0006816=NAS, GO:0016021=NAS, GO:0060356=ISS, GO:0006811=TAS} amino acid transport, blood coagulation, calcium ion transport, carbohydrate metabolic process, cell growth, ion transport, leucine import, leukocyte migration, transmembrane transport, tryptophan transport apical plasma membrane, cell surface, integral to membrane, melanosome, plasma membrane calcium:sodium antiporter activity, catalytic activity, cation binding, neutral amino acid transmembrane transporter activity, protein binding Human SLC40A1 BHF-UCL UniProtKB {GO:0005515=PMID:20817278, GO:0005886=GO_REF:0000054, GO:0005771=GO_REF:0000019, GO:0003158=GO_REF:0000019, GO:0006915=GO_REF:0000019, GO:0055085=Reactome:REACT_19118, GO:0060586=GO_REF:0000019, GO:0009653=PMID:10693807, GO:0008021=GO_REF:0000019, GO:0006879=PMID:12091367, GO:0060345=GO_REF:0000019, GO:0005737=PMID:10747949, GO:0005887=PMID:12091367, GO:0005381=PMID:12091367, GO:0016021=PMID:10747949, GO:0002260=GO_REF:0000019, GO:0034755=PMID:12091367} Q9NP59 Solute carrier family 40 member 1 protein 20110817 {GO:0005515=IPI, GO:0005886=IDA, GO:0005771=IEA, GO:0003158=IEA, GO:0006915=IEA, GO:0055085=TAS, GO:0060586=IEA, GO:0009653=TAS, GO:0008021=IEA, GO:0006879=IMP, GO:0060345=IEA, GO:0005737=TAS, GO:0005887=IC, GO:0005381=IMP, GO:0016021=TAS, GO:0002260=IEA, GO:0034755=IMP} anatomical structure morphogenesis, apoptotic process, cellular iron ion homeostasis, endothelium development, iron ion transmembrane transport, lymphocyte homeostasis, multicellular organismal iron ion homeostasis, spleen trabecula formation, transmembrane transport cytoplasm, integral to membrane, integral to plasma membrane, multivesicular body, plasma membrane, synaptic vesicle iron ion transmembrane transporter activity, protein binding Human GO:0005381 SLC41A1 Reactome UniProtKB {GO:0005886=Reactome:REACT_20680, GO:0008324=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_19118} Q8IVJ1 Solute carrier family 41 member 1 protein 20130301 {GO:0005886=TAS, GO:0008324=IEA, GO:0016021=IEA, GO:0055085=TAS} transmembrane transport integral to membrane, plasma membrane cation transmembrane transporter activity Human SLC41A2 Reactome UniProtKB {GO:0005886=Reactome:REACT_20680, GO:0008324=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_19118} Q96JW4 Solute carrier family 41 member 2 protein 20130301 {GO:0005886=TAS, GO:0008324=IEA, GO:0016021=IEA, GO:0055085=TAS} transmembrane transport integral to membrane, plasma membrane cation transmembrane transporter activity Human SLC41A3 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0008324=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q96GZ6 Solute carrier family 41 member 3 protein 20130413 {GO:0005886=IEA, GO:0008324=IEA, GO:0016021=IEA} integral to membrane, plasma membrane cation transmembrane transporter activity Human UniProtKB-SubCell:SL-0039 SLC43A1 Reactome UniProtKB {GO:0015804=PMID:12930836, GO:0005886=Reactome:REACT_13479, GO:0005887=PMID:12930836, GO:0006865=Reactome:REACT_13796, GO:0015175=PMID:12930836, GO:0015179=GO_REF:0000019, GO:0055085=Reactome:REACT_19118, GO:0006811=Reactome:REACT_19397} O75387 Large neutral amino acids transporter small subunit 3 protein 20130301 {GO:0015804=IDA, GO:0005886=TAS, GO:0005887=TAS, GO:0006865=TAS, GO:0015175=IDA, GO:0015179=IEA, GO:0055085=TAS, GO:0006811=TAS} amino acid transport, ion transport, neutral amino acid transport, transmembrane transport integral to plasma membrane, plasma membrane L-amino acid transmembrane transporter activity, neutral amino acid transmembrane transporter activity Human SLC43A2 Reactome UniProtKB {GO:0005886=Reactome:REACT_13741, GO:0006865=Reactome:REACT_13796, GO:0016021=GO_REF:0000037, GO:0015179=GO_REF:0000019, GO:0055085=Reactome:REACT_19118, GO:0006811=Reactome:REACT_19397} Q8N370 Large neutral amino acids transporter small subunit 4 protein 20130301 {GO:0005886=TAS, GO:0006865=TAS, GO:0016021=IEA, GO:0015179=IEA, GO:0055085=TAS, GO:0006811=TAS} amino acid transport, ion transport, transmembrane transport integral to membrane, plasma membrane L-amino acid transmembrane transporter activity Human SLC43A3 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0055085=GO_REF:0000002} Q8NBI5 Solute carrier family 43 member 3 protein 20130413 {GO:0016021=IEA, GO:0055085=IEA} transmembrane transport integral to membrane Human UniProtKB-KW:KW-0812 SLC44A1 Reactome UniProtKB {GO:0015220=PMID:10677542, GO:0005886=Reactome:REACT_20598, GO:0015871=PMID:10677542, GO:0005741=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0016021=PMID:10677542, GO:0006644=Reactome:REACT_120870, GO:0055085=Reactome:REACT_19118, GO:0046474=Reactome:REACT_121401, GO:0006656=Reactome:REACT_121238} Q8WWI5 Choline transporter-like protein 1 protein 20130301 {GO:0015220=TAS, GO:0005886=TAS, GO:0015871=TAS, GO:0005741=IEA, GO:0044281=TAS, GO:0016021=TAS, GO:0006644=TAS, GO:0055085=TAS, GO:0046474=TAS, GO:0006656=TAS} choline transport, glycerophospholipid biosynthetic process, phosphatidylcholine biosynthetic process, phospholipid metabolic process, small molecule metabolic process, transmembrane transport integral to membrane, mitochondrial outer membrane, plasma membrane choline transmembrane transporter activity Human SLC44A2 GOC UniProtKB {GO:0007165=PMID:12761501, GO:0015220=PMID:10677542, GO:0005886=Reactome:REACT_20598, GO:0015871=PMID:10677542, GO:0044281=Reactome:REACT_111217, GO:0004871=PMID:12761501, GO:0016021=PMID:10677542, GO:0006644=Reactome:REACT_120870, GO:0043123=PMID:12761501, GO:0055085=Reactome:REACT_19118, GO:0046474=Reactome:REACT_121401, GO:0006656=Reactome:REACT_121238} Q8IWA5 Choline transporter-like protein 2 protein 20130413 {GO:0007165=IMP, GO:0015220=TAS, GO:0005886=TAS, GO:0015871=TAS, GO:0044281=TAS, GO:0004871=IMP, GO:0016021=TAS, GO:0006644=TAS, GO:0043123=IMP, GO:0055085=TAS, GO:0046474=TAS, GO:0006656=TAS} choline transport, glycerophospholipid biosynthetic process, phosphatidylcholine biosynthetic process, phospholipid metabolic process, positive regulation of I-kappaB kinase/NF-kappaB cascade, signal transduction, small molecule metabolic process, transmembrane transport integral to membrane, plasma membrane choline transmembrane transporter activity, signal transducer activity Human SLC44A3 Reactome UniProtKB {GO:0005886=Reactome:REACT_20598, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0006644=Reactome:REACT_120870, GO:0055085=Reactome:REACT_19118, GO:0046474=Reactome:REACT_121401, GO:0006656=Reactome:REACT_121238} Q8N4M1 Choline transporter-like protein 3 protein 20130301 {GO:0005886=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0006644=TAS, GO:0055085=TAS, GO:0046474=TAS, GO:0006656=TAS} glycerophospholipid biosynthetic process, phosphatidylcholine biosynthetic process, phospholipid metabolic process, small molecule metabolic process, transmembrane transport integral to membrane, plasma membrane Human SLC45A1 UniProtKB UniProtKB {GO:0008643=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0015293=GO_REF:0000037} Q9Y2W3 Proton-associated sugar transporter A protein 20130413 {GO:0008643=IEA, GO:0016021=IEA, GO:0015293=IEA} carbohydrate transport integral to membrane symporter activity Human UniProtKB-KW:KW-0812 SLC45A4 UniProtKB UniProtKB {GO:0006810=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q5BKX6 Solute carrier family 45 member 4 protein 20130413 {GO:0006810=IEA, GO:0016021=IEA} transport integral to membrane Human UniProtKB-KW:KW-0812 SLC46A1 Reactome UniProtKB {GO:0005215=GO_REF:0000002, GO:0015232=GO_REF:0000019, GO:0005886=Reactome:REACT_25025, GO:0015884=PMID:17129779, GO:0006767=Reactome:REACT_11238, GO:0044281=Reactome:REACT_111217, GO:0008517=PMID:17129779, GO:0055085=Reactome:REACT_15518, GO:0006879=Reactome:REACT_25060, GO:0005737=GO_REF:0000024, GO:0016324=PMID:17475902, GO:0005542=GO_REF:0000037, GO:0006766=Reactome:REACT_11193, GO:0046655=Reactome:REACT_11167, GO:0016021=GO_REF:0000037} Q96NT5 Proton-coupled folate transporter protein 20130301 {GO:0005215=IEA, GO:0015232=IEA, GO:0005886=TAS, GO:0015884=IDA, GO:0006767=TAS, GO:0044281=TAS, GO:0008517=IDA, GO:0055085=TAS, GO:0006879=TAS, GO:0005737=ISS, GO:0016324=IDA, GO:0005542=IEA, GO:0006766=TAS, GO:0046655=TAS, GO:0016021=IEA} cellular iron ion homeostasis, folic acid metabolic process, folic acid transport, small molecule metabolic process, transmembrane transport, vitamin metabolic process, water-soluble vitamin metabolic process apical plasma membrane, cytoplasm, integral to membrane, plasma membrane folic acid binding, folic acid transporter activity, heme transporter activity, transporter activity Human SLC48A1 UniProtKB UniProtKB {GO:0015232=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005765=GO_REF:0000039, GO:0010008=GO_REF:0000039} Q6P1K1 Heme transporter HRG1 protein 20130413 {GO:0015232=IEA, GO:0016021=IEA, GO:0005765=IEA, GO:0010008=IEA} endosome membrane, integral to membrane, lysosomal membrane heme transporter activity Human UniProtKB-SubCell:SL-0100 SLC4A1 BHF-UCL UniProtKB {GO:0005515=PMID:16669616, GO:0006820=PMID:14734552, GO:0006821=GO_REF:0000024, GO:0008509=PMID:4027230, GO:0030018=GO_REF:0000024, GO:0005886=Reactome:REACT_121292, GO:0030506=PMID:379653, GO:0006873=PMID:8841202, GO:0003779=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0008022=GO_REF:0000019, GO:0055085=Reactome:REACT_19118, GO:0042803=PMID:379653, GO:0016323=PMID:12539048, GO:0005452=Reactome:REACT_121292, GO:0005887=PMID:379653, GO:0015301=PMID:14734552, GO:0015108=GO_REF:0000024, GO:0015701=Reactome:REACT_121380, GO:0030863=PMID:16669616, GO:0016021=PMID:1527044, GO:0043495=PMID:10950304, GO:0006811=Reactome:REACT_19397} P02730 Band 3 anion transport protein protein 20090206 {GO:0005515=IPI, GO:0006820=IDA, GO:0006821=ISS, GO:0008509=TAS, GO:0030018=ISS, GO:0005886=TAS, GO:0030506=IPI, GO:0006873=TAS, GO:0003779=IEA, GO:0044281=TAS, GO:0008022=IEA, GO:0055085=TAS, GO:0042803=IPI, GO:0016323=IDA, GO:0005452=TAS, GO:0005887=IDA, GO:0015301=IDA, GO:0015108=ISS, GO:0015701=TAS, GO:0030863=IDA, GO:0016021=NAS, GO:0043495=TAS, GO:0006811=TAS} anion transport, bicarbonate transport, cellular ion homeostasis, chloride transport, ion transport, small molecule metabolic process, transmembrane transport Z disc, basolateral plasma membrane, cortical cytoskeleton, integral to membrane, integral to plasma membrane, plasma membrane actin binding, anion transmembrane transporter activity, anion:anion antiporter activity, ankyrin binding, chloride transmembrane transporter activity, inorganic anion exchanger activity, protein C-terminus binding, protein anchor, protein binding, protein homodimerization activity Human SLC4A10 Reactome UniProtKB {GO:0006821=PMID:10993873, GO:0016323=GO_REF:0000019, GO:0005886=Reactome:REACT_19291, GO:0005452=GO_REF:0000002, GO:0015701=Reactome:REACT_19298, GO:0016021=PMID:10993873, GO:0006814=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0006885=GO_REF:0000019, GO:0006811=Reactome:REACT_19397, GO:0015293=GO_REF:0000037} Q6U841 Sodium-driven chloride bicarbonate exchanger protein 20130301 {GO:0006821=NAS, GO:0016323=IEA, GO:0005886=TAS, GO:0005452=IEA, GO:0015701=TAS, GO:0016021=NAS, GO:0006814=IEA, GO:0055085=TAS, GO:0006885=IEA, GO:0006811=TAS, GO:0015293=IEA} bicarbonate transport, chloride transport, ion transport, regulation of pH, sodium ion transport, transmembrane transport basolateral plasma membrane, integral to membrane, plasma membrane inorganic anion exchanger activity, symporter activity Human SLC4A11 GOC UniProtKB {GO:0046715=PMID:15525507, GO:0046713=PMID:15525507, GO:0035445=PMID:15525507, GO:0005272=PMID:15525507, GO:0030003=PMID:15525507, GO:0016323=PMID:15525507, GO:0042044=GO_REF:0000024, GO:0005452=GO_REF:0000002, GO:0015106=PMID:15525507, GO:0046983=PMID:22072594, GO:0015252=PMID:15525507, GO:0015701=PMID:15525507, GO:0035725=PMID:15525507, GO:0005351=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0009401=GO_REF:0000002, GO:0006814=PMID:15525507, GO:0015992=PMID:15525507} Q8NBS3 Sodium bicarbonate transporter-like protein 11 protein 20130413 {GO:0046715=IDA, GO:0046713=IDA, GO:0035445=IDA, GO:0005272=IDA, GO:0030003=IDA, GO:0016323=TAS, GO:0042044=ISS, GO:0005452=IEA, GO:0015106=IDA, GO:0046983=IDA, GO:0015252=IDA, GO:0015701=IDA, GO:0035725=IDA, GO:0005351=IEA, GO:0016021=IEA, GO:0009401=IEA, GO:0006814=IDA, GO:0015992=IDA} bicarbonate transport, borate transmembrane transport, borate transport, cellular cation homeostasis, fluid transport, phosphoenolpyruvate-dependent sugar phosphotransferase system, proton transport, sodium ion transmembrane transport, sodium ion transport basolateral plasma membrane, integral to membrane bicarbonate transmembrane transporter activity, borate transmembrane transporter activity, hydrogen ion channel activity, inorganic anion exchanger activity, protein dimerization activity, sodium channel activity, sugar:hydrogen symporter activity Human SLC4A1AP HPA UniProtKB {GO:0003725=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000052} Q9BWU0 Kanadaptin protein 20110516 {GO:0003725=IEA, GO:0005737=IEA, GO:0005634=IDA} cytoplasm, nucleus double-stranded RNA binding Human SLC4A2 Reactome UniProtKB {GO:0006820=PMID:3015590, GO:0008509=PMID:3015590, GO:0016323=GO_REF:0000019, GO:0005886=Reactome:REACT_19263, GO:0016020=PMID:3015590, GO:0005452=GO_REF:0000002, GO:0015108=GO_REF:0000019, GO:0015701=Reactome:REACT_19298, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0006811=Reactome:REACT_19397} P04920 Anion exchange protein 2 protein 20130301 {GO:0006820=TAS, GO:0008509=TAS, GO:0016323=IEA, GO:0005886=TAS, GO:0016020=TAS, GO:0005452=IEA, GO:0015108=IEA, GO:0015701=TAS, GO:0016021=IEA, GO:0055085=TAS, GO:0006811=TAS} anion transport, bicarbonate transport, ion transport, transmembrane transport basolateral plasma membrane, integral to membrane, membrane, plasma membrane anion transmembrane transporter activity, chloride transmembrane transporter activity, inorganic anion exchanger activity Human SLC4A3 Reactome UniProtKB {GO:0005886=Reactome:REACT_19263, GO:0016020=PMID:7923606, GO:0005452=GO_REF:0000002, GO:0005887=PMID:7923606, GO:0006810=PMID:7923606, GO:0015701=Reactome:REACT_19298, GO:0051453=GO_REF:0000019, GO:0016021=GO_REF:0000002, GO:0055085=Reactome:REACT_19118, GO:0006811=Reactome:REACT_19397} P48751 Anion exchange protein 3 protein 20130301 {GO:0005886=TAS, GO:0016020=TAS, GO:0005452=IEA, GO:0005887=TAS, GO:0006810=TAS, GO:0015701=TAS, GO:0051453=IEA, GO:0016021=IEA, GO:0055085=TAS, GO:0006811=TAS} bicarbonate transport, ion transport, regulation of intracellular pH, transmembrane transport, transport integral to membrane, integral to plasma membrane, membrane, plasma membrane inorganic anion exchanger activity Human SLC4A4 Reactome UniProtKB {GO:0005515=PMID:15563508, GO:0016323=GO_REF:0000039, GO:0005886=Reactome:REACT_19247, GO:0005452=GO_REF:0000002, GO:0005887=PMID:9235899, GO:0006810=PMID:9235899, GO:0015701=Reactome:REACT_19298, GO:0055085=Reactome:REACT_19118, GO:0008510=PMID:9651366, GO:0006811=Reactome:REACT_19397} Q9Y6R1 Electrogenic sodium bicarbonate cotransporter 1 protein 20130301 {GO:0005515=IPI, GO:0016323=IEA, GO:0005886=TAS, GO:0005452=IEA, GO:0005887=TAS, GO:0006810=TAS, GO:0015701=TAS, GO:0055085=TAS, GO:0008510=TAS, GO:0006811=TAS} bicarbonate transport, ion transport, transmembrane transport, transport basolateral plasma membrane, integral to plasma membrane, plasma membrane inorganic anion exchanger activity, protein binding, sodium:bicarbonate symporter activity Human SLC4A5 Reactome UniProtKB {GO:0008509=GO_REF:0000002, GO:0016324=GO_REF:0000039, GO:0005886=Reactome:REACT_19247, GO:0005452=GO_REF:0000002, GO:0015701=Reactome:REACT_19298, GO:0016021=PMID:10978526, GO:0055085=Reactome:REACT_19118, GO:0008510=PMID:10978526, GO:0006811=Reactome:REACT_19397} Q9BY07 Electrogenic sodium bicarbonate cotransporter 4 protein 20130301 {GO:0008509=IEA, GO:0016324=IEA, GO:0005886=TAS, GO:0005452=IEA, GO:0015701=TAS, GO:0016021=NAS, GO:0055085=TAS, GO:0008510=NAS, GO:0006811=TAS} bicarbonate transport, ion transport, transmembrane transport apical plasma membrane, integral to membrane, plasma membrane anion transmembrane transporter activity, inorganic anion exchanger activity, sodium:bicarbonate symporter activity Human SLC4A7 Reactome UniProtKB {GO:0005886=Reactome:REACT_19247, GO:0061299=GO_REF:0000019, GO:0032420=GO_REF:0000039, GO:0055085=Reactome:REACT_19118, GO:0060117=GO_REF:0000019, GO:0016323=GO_REF:0000039, GO:0016324=GO_REF:0000039, GO:0005452=GO_REF:0000002, GO:0046666=GO_REF:0000019, GO:0015701=Reactome:REACT_19298, GO:0016021=PMID:10347222, GO:0021747=GO_REF:0000019, GO:0008510=PMID:10347222, GO:0006811=Reactome:REACT_19397} Q9Y6M7 Sodium bicarbonate cotransporter 3 protein 20130301 {GO:0005886=TAS, GO:0061299=IEA, GO:0032420=IEA, GO:0055085=TAS, GO:0060117=IEA, GO:0016323=IEA, GO:0016324=IEA, GO:0005452=IEA, GO:0046666=IEA, GO:0015701=TAS, GO:0016021=NAS, GO:0021747=IEA, GO:0008510=NAS, GO:0006811=TAS} auditory receptor cell development, bicarbonate transport, cochlear nucleus development, ion transport, retina vasculature morphogenesis in camera-type eye, retinal cell programmed cell death, transmembrane transport apical plasma membrane, basolateral plasma membrane, integral to membrane, plasma membrane, stereocilium inorganic anion exchanger activity, sodium:bicarbonate symporter activity Human SLC4A8 Reactome UniProtKB {GO:0005886=Reactome:REACT_19291, GO:0005452=GO_REF:0000002, GO:0015701=Reactome:REACT_19298, GO:0016021=GO_REF:0000037, GO:0006814=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0006811=Reactome:REACT_19397} Q2Y0W8 Electroneutral sodium bicarbonate exchanger 1 protein 20130301 {GO:0005886=TAS, GO:0005452=IEA, GO:0015701=TAS, GO:0016021=IEA, GO:0006814=IEA, GO:0055085=TAS, GO:0006811=TAS} bicarbonate transport, ion transport, sodium ion transport, transmembrane transport integral to membrane, plasma membrane inorganic anion exchanger activity Human SLC50A1 GOC UniProtKB {GO:0005794=PMID:21107422, GO:0005886=PMID:21107422, GO:0000139=GO_REF:0000039, GO:0045815=PMID:8630032, GO:0042946=PMID:21107422, GO:0008643=GO_REF:0000037, GO:0005634=PMID:8630032, GO:0006310=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0012505=GO_REF:0000024, GO:0042947=PMID:21107422} Q9BRV3 Sugar transporter SWEET1 protein 20130413 {GO:0005794=IDA, GO:0005886=IDA, GO:0000139=IEA, GO:0045815=ISS, GO:0042946=IDA, GO:0008643=IEA, GO:0005634=IC, GO:0006310=IEA, GO:0016021=IEA, GO:0012505=ISS, GO:0042947=IDA} DNA recombination, carbohydrate transport, glucoside transport, positive regulation of gene expression, epigenetic Golgi apparatus, Golgi membrane, endomembrane system, integral to membrane, nucleus, plasma membrane glucoside transmembrane transporter activity Human SLC5A1 IntAct UniProtKB {GO:0005515=PMID:18455122, GO:0005886=Reactome:REACT_9525, GO:0005975=Reactome:REACT_474, GO:0031526=GO_REF:0000019, GO:0005412=PMID:8563765, GO:0044281=Reactome:REACT_111217, GO:0055085=Reactome:REACT_19118, GO:0008645=Reactome:REACT_9441, GO:0016324=GO_REF:0000019, GO:0050892=GO_REF:0000019, GO:0015758=PMID:8563765, GO:0005911=GO_REF:0000019, GO:0005887=PMID:8563765} P13866 Sodium/glucose cotransporter 1 protein 20130415 {GO:0005515=IPI, GO:0005886=TAS, GO:0005975=TAS, GO:0031526=IEA, GO:0005412=IDA, GO:0044281=TAS, GO:0055085=TAS, GO:0008645=TAS, GO:0016324=IEA, GO:0050892=IEA, GO:0015758=IMP, GO:0005911=IEA, GO:0005887=TAS} carbohydrate metabolic process, glucose transport, hexose transport, intestinal absorption, small molecule metabolic process, transmembrane transport apical plasma membrane, brush border membrane, cell-cell junction, integral to plasma membrane, plasma membrane glucose:sodium symporter activity, protein binding Human UniProtKB:P00533 SLC5A3 Reactome UniProtKB {GO:0043576=GO_REF:0000019, GO:0006020=GO_REF:0000019, GO:0005886=Reactome:REACT_19415, GO:0005887=PMID:1372904, GO:0007422=GO_REF:0000019, GO:0006810=PMID:1372904, GO:0016021=PMID:7789985, GO:0055085=Reactome:REACT_19118, GO:0005367=PMID:1372904} P53794 Sodium/myo-inositol cotransporter protein 20130301 {GO:0043576=IEA, GO:0006020=IEA, GO:0005886=TAS, GO:0005887=TAS, GO:0007422=IEA, GO:0006810=TAS, GO:0016021=TAS, GO:0055085=TAS, GO:0005367=TAS} inositol metabolic process, peripheral nervous system development, regulation of respiratory gaseous exchange, transmembrane transport, transport integral to membrane, integral to plasma membrane, plasma membrane myo-inositol:sodium symporter activity Human SLC5A5 Reactome UniProtKB {GO:0005886=Reactome:REACT_19340, GO:0008507=GO_REF:0000019, GO:0005634=PMID:15961562, GO:0044281=Reactome:REACT_111217, GO:0015111=PMID:12021185, GO:0055085=Reactome:REACT_19118, GO:0034641=Reactome:REACT_13, GO:0071371=PMID:12021185, GO:0006810=PMID:8806637, GO:0006590=Reactome:REACT_15292, GO:0016021=GO_REF:0000037, GO:0071320=PMID:12021185, GO:0015705=PMID:12021185, GO:0006811=Reactome:REACT_19397} Q92911 Sodium/iodide cotransporter protein 20130301 {GO:0005886=TAS, GO:0008507=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0015111=IMP, GO:0055085=TAS, GO:0034641=TAS, GO:0071371=IEP, GO:0006810=TAS, GO:0006590=TAS, GO:0016021=IEA, GO:0071320=IEP, GO:0015705=IMP, GO:0006811=TAS} cellular nitrogen compound metabolic process, cellular response to cAMP, cellular response to gonadotropin stimulus, iodide transport, ion transport, small molecule metabolic process, thyroid hormone generation, transmembrane transport, transport integral to membrane, nucleus, plasma membrane iodide transmembrane transporter activity, sodium:iodide symporter activity Human SLC5A6 Reactome UniProtKB {GO:0012506=GO_REF:0000019, GO:0015887=GO_REF:0000019, GO:0015939=Reactome:REACT_11172, GO:0005886=Reactome:REACT_22320, GO:0006768=Reactome:REACT_11153, GO:0006767=Reactome:REACT_11238, GO:0044281=Reactome:REACT_111217, GO:0031526=GO_REF:0000019, GO:0055085=Reactome:REACT_19118, GO:0016020=PMID:9516450, GO:0005887=PMID:9516450, GO:0006766=Reactome:REACT_11193, GO:0008523=GO_REF:0000019, GO:0006810=PMID:9516450, GO:0016021=GO_REF:0000038, GO:0015878=GO_REF:0000019} Q9Y289 Sodium-dependent multivitamin transporter protein 20130301 {GO:0012506=IEA, GO:0015887=IEA, GO:0015939=TAS, GO:0005886=TAS, GO:0006768=TAS, GO:0006767=TAS, GO:0044281=TAS, GO:0031526=IEA, GO:0055085=TAS, GO:0016020=TAS, GO:0005887=TAS, GO:0006766=TAS, GO:0008523=IEA, GO:0006810=TAS, GO:0016021=IEA, GO:0015878=IEA} biotin metabolic process, biotin transport, pantothenate metabolic process, pantothenate transmembrane transport, small molecule metabolic process, transmembrane transport, transport, vitamin metabolic process, water-soluble vitamin metabolic process brush border membrane, integral to membrane, integral to plasma membrane, membrane, plasma membrane, vesicle membrane sodium-dependent multivitamin transmembrane transporter activity Human SLC5A7 Reactome UniProtKB {GO:0033265=GO_REF:0000019, GO:0015220=PMID:11068039, GO:0005886=Reactome:REACT_20595, GO:0008292=PMID:11068039, GO:0043025=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0005307=PMID:12237312, GO:0007274=GO_REF:0000019, GO:0016021=PMID:11027560, GO:0055085=Reactome:REACT_19118, GO:0007269=Reactome:REACT_13723, GO:0007271=GO_REF:0000019} Q9GZV3 High affinity choline transporter 1 protein 20130301 {GO:0033265=IEA, GO:0015220=IMP, GO:0005886=TAS, GO:0008292=IMP, GO:0043025=IEA, GO:0007268=TAS, GO:0005307=IMP, GO:0007274=IEA, GO:0016021=IDA, GO:0055085=TAS, GO:0007269=TAS, GO:0007271=IEA} acetylcholine biosynthetic process, neuromuscular synaptic transmission, neurotransmitter secretion, synaptic transmission, synaptic transmission, cholinergic, transmembrane transport integral to membrane, neuronal cell body, plasma membrane choline binding, choline transmembrane transporter activity, choline:sodium symporter activity Human SLC6A1 Reactome UniProtKB {GO:0010288=GO_REF:0000019, GO:0030424=GO_REF:0000019, GO:0005886=Reactome:REACT_20659, GO:0009986=GO_REF:0000019, GO:0005328=GO_REF:0000002, GO:0051939=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0009636=GO_REF:0000019, GO:0014054=GO_REF:0000019, GO:0042220=GO_REF:0000019, GO:0055085=Reactome:REACT_19118, GO:0014074=GO_REF:0000019, GO:0007269=Reactome:REACT_13723, GO:0051592=GO_REF:0000019, GO:0016020=PMID:2387399, GO:0005887=GO_REF:0000002, GO:0009744=GO_REF:0000019, GO:0006810=PMID:8530094, GO:0032229=GO_REF:0000019, GO:0051260=GO_REF:0000019, GO:0016021=PMID:8530094, GO:0007612=GO_REF:0000019, GO:0005332=GO_REF:0000019, GO:0032355=GO_REF:0000019} P30531 Sodium- and chloride-dependent GABA transporter 1 protein 20130301 {GO:0010288=IEA, GO:0030424=IEA, GO:0005886=TAS, GO:0009986=IEA, GO:0005328=IEA, GO:0051939=IEA, GO:0007268=TAS, GO:0009636=IEA, GO:0014054=IEA, GO:0042220=IEA, GO:0055085=TAS, GO:0014074=IEA, GO:0007269=TAS, GO:0051592=IEA, GO:0016020=TAS, GO:0005887=IEA, GO:0009744=IEA, GO:0006810=NAS, GO:0032229=IEA, GO:0051260=IEA, GO:0016021=TAS, GO:0007612=IEA, GO:0005332=IEA, GO:0032355=IEA} gamma-aminobutyric acid import, learning, negative regulation of synaptic transmission, GABAergic, neurotransmitter secretion, positive regulation of gamma-aminobutyric acid secretion, protein homooligomerization, response to calcium ion, response to cocaine, response to estradiol stimulus, response to lead ion, response to purine-containing compound, response to sucrose stimulus, response to toxic substance, synaptic transmission, transmembrane transport, transport axon, cell surface, integral to membrane, integral to plasma membrane, membrane, plasma membrane gamma-aminobutyric acid:sodium symporter activity, neurotransmitter:sodium symporter activity Human SLC6A12 Reactome UniProtKB {GO:0071474=GO_REF:0000019, GO:0010033=GO_REF:0000019, GO:0005886=Reactome:REACT_13561, GO:0005328=GO_REF:0000002, GO:0006865=Reactome:REACT_13796, GO:0009992=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0055085=Reactome:REACT_19118, GO:0007269=Reactome:REACT_13723, GO:0005887=GO_REF:0000002, GO:0006810=PMID:7861179, GO:0016021=PMID:7861179, GO:0005332=GO_REF:0000002, GO:0006811=Reactome:REACT_19397} P48065 Sodium- and chloride-dependent betaine transporter protein 20130301 {GO:0071474=IEA, GO:0010033=IEA, GO:0005886=TAS, GO:0005328=IEA, GO:0006865=TAS, GO:0009992=IEA, GO:0007268=TAS, GO:0055085=TAS, GO:0007269=TAS, GO:0005887=IEA, GO:0006810=TAS, GO:0016021=TAS, GO:0005332=IEA, GO:0006811=TAS} amino acid transport, cellular hyperosmotic response, cellular water homeostasis, ion transport, neurotransmitter secretion, response to organic substance, synaptic transmission, transmembrane transport, transport integral to membrane, integral to plasma membrane, plasma membrane gamma-aminobutyric acid:sodium symporter activity, neurotransmitter:sodium symporter activity Human SLC6A13 Reactome UniProtKB {GO:0005886=Reactome:REACT_20659, GO:0005887=GO_REF:0000002, GO:0005328=GO_REF:0000002, GO:0007268=Reactome:REACT_13685, GO:0042165=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0055085=Reactome:REACT_19118, GO:0005332=GO_REF:0000019, GO:0007269=Reactome:REACT_13723} Q9NSD5 Sodium- and chloride-dependent GABA transporter 2 protein 20130301 {GO:0005886=TAS, GO:0005887=IEA, GO:0005328=IEA, GO:0007268=TAS, GO:0042165=IEA, GO:0016021=IEA, GO:0055085=TAS, GO:0005332=IEA, GO:0007269=TAS} neurotransmitter secretion, synaptic transmission, transmembrane transport integral to membrane, integral to plasma membrane, plasma membrane gamma-aminobutyric acid:sodium symporter activity, neurotransmitter binding, neurotransmitter:sodium symporter activity Human SLC6A15 Reactome UniProtKB {GO:0005886=Reactome:REACT_13593, GO:0005328=GO_REF:0000002, GO:0005326=PMID:11112352, GO:0006865=Reactome:REACT_13796, GO:0005298=GO_REF:0000019, GO:0055085=Reactome:REACT_19118, GO:0015804=PMID:16226721, GO:0015820=GO_REF:0000024, GO:0005887=GO_REF:0000002, GO:0015824=GO_REF:0000024, GO:0006836=PMID:11112352, GO:0016021=PMID:11112352, GO:0006811=Reactome:REACT_19397} Q9H2J7 Sodium-dependent neutral amino acid transporter B(0)AT2 protein 20130301 {GO:0005886=TAS, GO:0005328=IEA, GO:0005326=NAS, GO:0006865=TAS, GO:0005298=IEA, GO:0055085=TAS, GO:0015804=IDA, GO:0015820=ISS, GO:0005887=IEA, GO:0015824=ISS, GO:0006836=NAS, GO:0016021=NAS, GO:0006811=TAS} amino acid transport, ion transport, leucine transport, neurotransmitter transport, neutral amino acid transport, proline transport, transmembrane transport integral to membrane, integral to plasma membrane, plasma membrane neurotransmitter transporter activity, neurotransmitter:sodium symporter activity, proline:sodium symporter activity Human SLC6A17 UniProtKB UniProtKB {GO:0015804=GO_REF:0000024, GO:0015816=GO_REF:0000024, GO:0015820=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0005887=GO_REF:0000002, GO:0005328=GO_REF:0000002, GO:0015824=GO_REF:0000024, GO:0030672=GO_REF:0000039, GO:0032328=GO_REF:0000024, GO:0008021=GO_REF:0000024} Q9H1V8 Sodium-dependent neutral amino acid transporter SLC6A17 protein 20110218 {GO:0015804=ISS, GO:0015816=ISS, GO:0015820=ISS, GO:0030054=IEA, GO:0005887=IEA, GO:0005328=IEA, GO:0015824=ISS, GO:0030672=IEA, GO:0032328=ISS, GO:0008021=ISS} alanine transport, glycine transport, leucine transport, neutral amino acid transport, proline transport cell junction, integral to plasma membrane, synaptic vesicle, synaptic vesicle membrane neurotransmitter:sodium symporter activity Human UniProtKB:P31662 SLC6A2 Reactome UniProtKB {GO:0005515=PMID:17156375, GO:0005886=Reactome:REACT_20592, GO:0005328=GO_REF:0000002, GO:0007268=PMID:2008212, GO:0055085=Reactome:REACT_19118, GO:0016020=PMID:2008212, GO:0005887=GO_REF:0000002, GO:0006810=PMID:2008212, GO:0008504=PMID:16024787, GO:0048265=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0005334=PMID:2008212, GO:0015844=PMID:16024787} P23975 Sodium-dependent noradrenaline transporter protein 20130301 {GO:0005515=IPI, GO:0005886=TAS, GO:0005328=IEA, GO:0007268=TAS, GO:0055085=TAS, GO:0016020=TAS, GO:0005887=IEA, GO:0006810=TAS, GO:0008504=IDA, GO:0048265=IEA, GO:0016021=IEA, GO:0005334=TAS, GO:0015844=IDA} monoamine transport, response to pain, synaptic transmission, transmembrane transport, transport integral to membrane, integral to plasma membrane, membrane, plasma membrane monoamine transmembrane transporter activity, neurotransmitter:sodium symporter activity, norepinephrine:sodium symporter activity, protein binding Human SLC6A20 GOC UniProtKB {GO:0015816=PMID:19033659, GO:0016324=GO_REF:0000024, GO:0005886=Reactome:REACT_13591, GO:0015171=PMID:15632147, GO:0005887=GO_REF:0000002, GO:0005328=GO_REF:0000002, GO:0015824=PMID:19033659, GO:0006865=Reactome:REACT_13796, GO:0003333=PMID:15632147, GO:0055085=Reactome:REACT_19118, GO:0006811=Reactome:REACT_19397} Q9NP91 Sodium- and chloride-dependent transporter XTRP3 protein 20130413 {GO:0015816=IMP, GO:0016324=ISS, GO:0005886=TAS, GO:0015171=IDA, GO:0005887=IEA, GO:0005328=IEA, GO:0015824=IMP, GO:0006865=TAS, GO:0003333=IDA, GO:0055085=TAS, GO:0006811=TAS} amino acid transmembrane transport, amino acid transport, glycine transport, ion transport, proline transport, transmembrane transport apical plasma membrane, integral to plasma membrane, plasma membrane amino acid transmembrane transporter activity, neurotransmitter:sodium symporter activity Human SLC6A3 Reactome UniProtKB {GO:0005515=PMID:12958153, GO:0021984=GO_REF:0000019, GO:0008219=GO_REF:0000037, GO:0007608=GO_REF:0000019, GO:0030424=PMID:12958153, GO:0005329=PMID:10823899, GO:0005886=Reactome:REACT_15468, GO:0045471=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0002020=GO_REF:0000019, GO:0042220=GO_REF:0000019, GO:0051591=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0042053=GO_REF:0000019, GO:0042416=GO_REF:0000019, GO:0005737=PMID:10823899, GO:0008144=GO_REF:0000019, GO:0010039=GO_REF:0000019, GO:0006810=PMID:8628395, GO:0043025=PMID:12958153, GO:0007626=GO_REF:0000019, GO:0040018=GO_REF:0000019, GO:0005330=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0060134=GO_REF:0000019, GO:0015872=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0005102=GO_REF:0000019, GO:0035240=GO_REF:0000019, GO:0055085=Reactome:REACT_19118, GO:0047485=GO_REF:0000019, GO:0007595=GO_REF:0000019, GO:0005887=GO_REF:0000002, GO:0008504=PMID:16024787, GO:0042420=GO_REF:0000019, GO:0042136=Reactome:REACT_13583, GO:0016021=PMID:8628395, GO:0015844=PMID:16024787, GO:0035094=GO_REF:0000019} Q01959 Sodium-dependent dopamine transporter protein 20130301 {GO:0005515=IPI, GO:0021984=IEA, GO:0008219=IEA, GO:0007608=IEA, GO:0030424=IDA, GO:0005329=TAS, GO:0005886=TAS, GO:0045471=IEA, GO:0007268=TAS, GO:0002020=IEA, GO:0042220=IEA, GO:0051591=IEA, GO:0032403=IEA, GO:0042053=IEA, GO:0042416=IEA, GO:0005737=TAS, GO:0008144=IEA, GO:0010039=IEA, GO:0006810=TAS, GO:0043025=IDA, GO:0007626=IEA, GO:0040018=IEA, GO:0005330=IEA, GO:0042493=IEA, GO:0060134=IEA, GO:0015872=IEA, GO:0007568=IEA, GO:0005102=IEA, GO:0035240=IEA, GO:0055085=TAS, GO:0047485=IEA, GO:0007595=IEA, GO:0005887=IEA, GO:0008504=IDA, GO:0042420=IEA, GO:0042136=TAS, GO:0016021=TAS, GO:0015844=IDA, GO:0035094=IEA} adenohypophysis development, aging, cell death, dopamine biosynthetic process, dopamine catabolic process, dopamine transport, lactation, locomotory behavior, monoamine transport, neurotransmitter biosynthetic process, positive regulation of multicellular organism growth, prepulse inhibition, regulation of dopamine metabolic process, response to cAMP, response to cocaine, response to drug, response to ethanol, response to iron ion, response to nicotine, sensory perception of smell, synaptic transmission, transmembrane transport, transport axon, cytoplasm, integral to membrane, integral to plasma membrane, neuronal cell body, plasma membrane dopamine binding, dopamine transmembrane transporter activity, dopamine:sodium symporter activity, drug binding, monoamine transmembrane transporter activity, protease binding, protein N-terminus binding, protein binding, protein complex binding, receptor binding Human SLC6A4 BHF-UCL UniProtKB {GO:0005515=PMID:11343649, GO:0050998=GO_REF:0000019, GO:0043005=GO_REF:0000019, GO:0005886=PMID:16870614, GO:0005328=GO_REF:0000002, GO:0071300=GO_REF:0000019, GO:0021941=GO_REF:0000019, GO:0051259=GO_REF:0000024, GO:0042803=GO_REF:0000019, GO:0005829=PMID:19270731, GO:0021794=PMID:18378990, GO:0051015=GO_REF:0000024, GO:0042310=GO_REF:0000019, GO:0005335=PMID:19270731, GO:0051260=GO_REF:0000019, GO:0007613=GO_REF:0000019, GO:0017075=GO_REF:0000019, GO:0032355=GO_REF:0000019, GO:0006837=PMID:19270731, GO:0046621=GO_REF:0000024, GO:0001666=GO_REF:0000019, GO:0017137=PMID:18227069, GO:0015222=PMID:19270731, GO:0007584=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0009636=PMID:17575980, GO:0045787=GO_REF:0000019, GO:0019811=GO_REF:0000019, GO:0012505=PMID:17506858, GO:0042713=GO_REF:0000019, GO:0048854=GO_REF:0000024, GO:0010628=GO_REF:0000019, GO:0045665=GO_REF:0000019, GO:0005887=PMID:19270731, GO:0032227=GO_REF:0000019, GO:0035176=GO_REF:0000024, GO:0051610=PMID:19270731, GO:0008504=PMID:16024787, GO:0007623=GO_REF:0000019, GO:0017022=GO_REF:0000019, GO:0045121=PMID:16870614, GO:0016021=GO_REF:0000038, GO:0015844=PMID:16024787, GO:0010008=GO_REF:0000039, GO:0071321=GO_REF:0000019} P31645 Sodium-dependent serotonin transporter protein 20120328 {GO:0005515=IPI, GO:0050998=IEA, GO:0043005=IEA, GO:0005886=IDA, GO:0005328=IEA, GO:0071300=IEA, GO:0021941=IEA, GO:0051259=ISS, GO:0042803=IEA, GO:0005829=IDA, GO:0021794=IMP, GO:0051015=ISS, GO:0042310=IEA, GO:0005335=IMP, GO:0051260=IEA, GO:0007613=IEA, GO:0017075=IEA, GO:0032355=IEA, GO:0006837=IDA, GO:0046621=ISS, GO:0001666=IEA, GO:0017137=IPI, GO:0015222=IMP, GO:0007584=IEA, GO:0042493=IEA, GO:0009636=IDA, GO:0045787=IEA, GO:0019811=IEA, GO:0012505=IDA, GO:0042713=IEA, GO:0048854=ISS, GO:0010628=IEA, GO:0045665=IEA, GO:0005887=IC, GO:0032227=IEA, GO:0035176=ISS, GO:0051610=IDA, GO:0008504=IDA, GO:0007623=IEA, GO:0017022=IEA, GO:0045121=IDA, GO:0016021=IEA, GO:0015844=IDA, GO:0010008=IEA, GO:0071321=IEA} brain morphogenesis, cellular response to cGMP, cellular response to retinoic acid, circadian rhythm, memory, monoamine transport, negative regulation of cerebellar granule cell precursor proliferation, negative regulation of neuron differentiation, negative regulation of organ growth, negative regulation of synaptic transmission, dopaminergic, positive regulation of cell cycle, positive regulation of gene expression, protein homooligomerization, protein oligomerization, response to drug, response to estradiol stimulus, response to hypoxia, response to nutrient, response to toxic substance, serotonin transport, serotonin uptake, social behavior, sperm ejaculation, thalamus development, vasoconstriction cytosol, endomembrane system, endosome membrane, integral to membrane, integral to plasma membrane, membrane raft, neuron projection, plasma membrane Rab GTPase binding, actin filament binding, cocaine binding, monoamine transmembrane transporter activity, myosin binding, neurotransmitter:sodium symporter activity, nitric-oxide synthase binding, protein binding, protein homodimerization activity, serotonin transmembrane transporter activity, serotonin:sodium symporter activity, syntaxin-1 binding Human UniProtKB:Q60857 SLC6A5 Reactome UniProtKB {GO:0015375=PMID:9845349, GO:0005886=Reactome:REACT_20620, GO:0005328=GO_REF:0000002, GO:0006810=PMID:9845349, GO:0007268=PMID:9845349, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_19118} Q9Y345 Sodium- and chloride-dependent glycine transporter 2 protein 20130301 {GO:0015375=TAS, GO:0005886=TAS, GO:0005328=IEA, GO:0006810=TAS, GO:0007268=TAS, GO:0016021=IEA, GO:0055085=TAS} synaptic transmission, transmembrane transport, transport integral to membrane, plasma membrane glycine:sodium symporter activity, neurotransmitter:sodium symporter activity Human SLC6A6 Reactome UniProtKB {GO:0006520=PMID:8010975, GO:0005886=Reactome:REACT_13704, GO:0005887=GO_REF:0000002, GO:0005328=GO_REF:0000002, GO:0015734=GO_REF:0000019, GO:0006865=Reactome:REACT_13796, GO:0006810=PMID:8010975, GO:0016021=PMID:8010975, GO:0055085=Reactome:REACT_19118, GO:0006811=Reactome:REACT_19397, GO:0030977=GO_REF:0000019, GO:0005369=GO_REF:0000019} P31641 Sodium- and chloride-dependent taurine transporter protein 20130301 {GO:0006520=TAS, GO:0005886=TAS, GO:0005887=IEA, GO:0005328=IEA, GO:0015734=IEA, GO:0006865=TAS, GO:0006810=TAS, GO:0016021=TAS, GO:0055085=TAS, GO:0006811=TAS, GO:0030977=IEA, GO:0005369=IEA} amino acid transport, cellular amino acid metabolic process, ion transport, taurine transport, transmembrane transport, transport integral to membrane, integral to plasma membrane, plasma membrane neurotransmitter:sodium symporter activity, taurine binding, taurine:sodium symporter activity Human SLC6A8 Reactome UniProtKB {GO:0015881=PMID:8661037, GO:0015220=GO_REF:0000019, GO:0005886=Reactome:REACT_11191, GO:0005328=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0005575=GO_REF:0000015, GO:0034641=Reactome:REACT_13, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0006936=PMID:8661155, GO:0006600=Reactome:REACT_813, GO:0005887=GO_REF:0000002, GO:0006810=PMID:7953292, GO:0016021=PMID:7953292, GO:0005308=PMID:8661037, GO:0005309=GO_REF:0000002} P48029 Sodium- and chloride-dependent creatine transporter 1 protein 20130301 {GO:0015881=NAS, GO:0015220=IEA, GO:0005886=TAS, GO:0005328=IEA, GO:0044281=TAS, GO:0005575=ND, GO:0034641=TAS, GO:0003674=ND, GO:0008150=ND, GO:0006936=TAS, GO:0006600=TAS, GO:0005887=IEA, GO:0006810=TAS, GO:0016021=TAS, GO:0005308=NAS, GO:0005309=IEA} biological_process, cellular nitrogen compound metabolic process, creatine metabolic process, creatine transport, muscle contraction, small molecule metabolic process, transport cellular_component, integral to membrane, integral to plasma membrane, plasma membrane choline transmembrane transporter activity, creatine transmembrane transporter activity, creatine:sodium symporter activity, molecular_function, neurotransmitter:sodium symporter activity Human SLC6A9 Reactome UniProtKB {GO:0015375=PMID:8183239, GO:0005886=Reactome:REACT_20620, GO:0016020=PMID:8183239, GO:0005887=GO_REF:0000002, GO:0005328=GO_REF:0000002, GO:0005283=GO_REF:0000002, GO:0006810=PMID:8183239, GO:0015187=GO_REF:0000019, GO:0055085=Reactome:REACT_19118} P48067 Sodium- and chloride-dependent glycine transporter 1 protein 20130301 {GO:0015375=TAS, GO:0005886=TAS, GO:0016020=TAS, GO:0005887=IEA, GO:0005328=IEA, GO:0005283=IEA, GO:0006810=TAS, GO:0015187=IEA, GO:0055085=TAS} transmembrane transport, transport integral to plasma membrane, membrane, plasma membrane glycine transmembrane transporter activity, glycine:sodium symporter activity, neurotransmitter:sodium symporter activity, sodium:amino acid symporter activity Human SLC7A1 ENSEMBL UniProtKB {GO:0016020=GO_REF:0000002, GO:0005886=Reactome:REACT_14850, GO:0005887=PMID:1718082, GO:0015181=GO_REF:0000019, GO:0006865=Reactome:REACT_13796, GO:0006810=PMID:1348489, GO:0055085=Reactome:REACT_19118, GO:0006811=Reactome:REACT_19397} Q5JR49 High affinity cationic amino acid transporter 1 protein 20130413 {GO:0016020=IEA, GO:0005886=TAS, GO:0005887=TAS, GO:0015181=IEA, GO:0006865=TAS, GO:0006810=NAS, GO:0055085=TAS, GO:0006811=TAS} amino acid transport, ion transport, transmembrane transport, transport integral to plasma membrane, membrane, plasma membrane arginine transmembrane transporter activity Human Ensembl:ENSMUSP00000046714 SLC7A10 GOC UniProtKB {GO:0005886=Reactome:REACT_16988, GO:0006865=Reactome:REACT_13796, GO:0050900=Reactome:REACT_12051, GO:0055085=Reactome:REACT_19118, GO:0015804=PMID:10863037, GO:0015194=PMID:10863037, GO:0015171=GO_REF:0000002, GO:0042942=GO_REF:0000019, GO:0016020=PMID:10734121, GO:0042941=GO_REF:0000019, GO:0005887=PMID:10863037, GO:0007596=Reactome:REACT_604, GO:0015825=PMID:10863037, GO:0015175=PMID:10863037, GO:0016021=GO_REF:0000038, GO:0006811=Reactome:REACT_19397} Q9NS82 Asc-type amino acid transporter 1 protein 20130413 {GO:0005886=TAS, GO:0006865=TAS, GO:0050900=TAS, GO:0055085=TAS, GO:0015804=IDA, GO:0015194=TAS, GO:0015171=IEA, GO:0042942=IEA, GO:0016020=TAS, GO:0042941=IEA, GO:0005887=NAS, GO:0007596=TAS, GO:0015825=TAS, GO:0015175=IDA, GO:0016021=IEA, GO:0006811=TAS} D-alanine transport, D-serine transport, L-serine transport, amino acid transport, blood coagulation, ion transport, leukocyte migration, neutral amino acid transport, transmembrane transport integral to membrane, integral to plasma membrane, membrane, plasma membrane L-serine transmembrane transporter activity, amino acid transmembrane transporter activity, neutral amino acid transmembrane transporter activity Human SLC7A11 Reactome UniProtKB {GO:0005791=GO_REF:0000019, GO:0015327=PMID:10206947, GO:0070306=GO_REF:0000019, GO:0005886=Reactome:REACT_16988, GO:0006865=Reactome:REACT_13796, GO:0009636=PMID:17575980, GO:0050900=Reactome:REACT_12051, GO:0055085=Reactome:REACT_19118, GO:0070527=GO_REF:0000019, GO:0015171=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0007420=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0005856=GO_REF:0000019, GO:0006979=GO_REF:0000019, GO:0035094=GO_REF:0000019, GO:0006811=Reactome:REACT_19397} Q9UPY5 Cystine/glutamate transporter protein 20130213 {GO:0005791=IEA, GO:0015327=TAS, GO:0070306=IEA, GO:0005886=TAS, GO:0006865=TAS, GO:0009636=IDA, GO:0050900=TAS, GO:0055085=TAS, GO:0070527=IEA, GO:0015171=IEA, GO:0007596=TAS, GO:0007420=IEA, GO:0016021=IEA, GO:0005856=IEA, GO:0006979=IEA, GO:0035094=IEA, GO:0006811=TAS} amino acid transport, blood coagulation, brain development, ion transport, lens fiber cell differentiation, leukocyte migration, platelet aggregation, response to nicotine, response to oxidative stress, response to toxic substance, transmembrane transport cytoskeleton, integral to membrane, plasma membrane, rough endoplasmic reticulum amino acid transmembrane transporter activity, cystine:glutamate antiporter activity Human SLC7A14 UniProtKB UniProtKB {GO:0015171=GO_REF:0000002, GO:0010923=PMID:19389623, GO:0016021=GO_REF:0000037} Q8TBB6 Probable cationic amino acid transporter protein 20111103 {GO:0015171=IEA, GO:0010923=IDA, GO:0016021=IEA} negative regulation of phosphatase activity integral to membrane amino acid transmembrane transporter activity Human SLC7A2 HPA UniProtKB {GO:0006520=PMID:8954799, GO:0005886=Reactome:REACT_14848, GO:0043030=GO_REF:0000019, GO:0006865=Reactome:REACT_13796, GO:0050727=GO_REF:0000019, GO:0055085=Reactome:REACT_19118, GO:0002537=GO_REF:0000019, GO:0005289=GO_REF:0000019, GO:0006809=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0042116=GO_REF:0000019, GO:0016020=PMID:8954799, GO:0005887=PMID:8954799, GO:0006810=PMID:8954799, GO:0015174=PMID:8954799, GO:0000064=GO_REF:0000019, GO:0006811=Reactome:REACT_19397, GO:0015189=GO_REF:0000019} P52569 Low affinity cationic amino acid transporter 2 protein 20080818 {GO:0006520=TAS, GO:0005886=TAS, GO:0043030=IEA, GO:0006865=TAS, GO:0050727=IEA, GO:0055085=TAS, GO:0002537=IEA, GO:0005289=IEA, GO:0006809=IEA, GO:0005737=IDA, GO:0042116=IEA, GO:0016020=TAS, GO:0005887=TAS, GO:0006810=TAS, GO:0015174=TAS, GO:0000064=IEA, GO:0006811=TAS, GO:0015189=IEA} amino acid transport, cellular amino acid metabolic process, ion transport, macrophage activation, nitric oxide biosynthetic process, nitric oxide production involved in inflammatory response, regulation of inflammatory response, regulation of macrophage activation, transmembrane transport, transport cytoplasm, integral to plasma membrane, membrane, plasma membrane L-lysine transmembrane transporter activity, L-ornithine transmembrane transporter activity, basic amino acid transmembrane transporter activity, high affinity arginine transmembrane transporter activity Human SLC7A3 Reactome UniProtKB {GO:0015326=GO_REF:0000019, GO:0005886=Reactome:REACT_14813, GO:0015181=GO_REF:0000019, GO:0006865=Reactome:REACT_13796, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0006811=Reactome:REACT_19397, GO:0015189=GO_REF:0000019} Q8WY07 Cationic amino acid transporter 3 protein 20130301 {GO:0015326=IEA, GO:0005886=TAS, GO:0015181=IEA, GO:0006865=TAS, GO:0016021=IEA, GO:0055085=TAS, GO:0006811=TAS, GO:0015189=IEA} amino acid transport, ion transport, transmembrane transport integral to membrane, plasma membrane L-lysine transmembrane transporter activity, arginine transmembrane transporter activity, cationic amino acid transmembrane transporter activity Human SLC7A5 Reactome UniProtKB {GO:0006520=PMID:9751058, GO:0005886=Reactome:REACT_16988, GO:0006865=Reactome:REACT_13796, GO:0050900=Reactome:REACT_12051, GO:0055085=Reactome:REACT_19118, GO:0030154=GO_REF:0000037, GO:0007399=GO_REF:0000037, GO:0005829=GO_REF:0000039, GO:0015804=GO_REF:0000024, GO:0016324=GO_REF:0000039, GO:0015171=GO_REF:0000024, GO:0007596=Reactome:REACT_604, GO:0042605=GO_REF:0000024, GO:0015175=PMID:9751058, GO:0006810=PMID:9751058, GO:0016021=GO_REF:0000037, GO:0015179=GO_REF:0000019, GO:0006811=Reactome:REACT_19397} Q01650 Large neutral amino acids transporter small subunit 1 protein 20130213 {GO:0006520=TAS, GO:0005886=TAS, GO:0006865=TAS, GO:0050900=TAS, GO:0055085=TAS, GO:0030154=IEA, GO:0007399=IEA, GO:0005829=IEA, GO:0015804=ISS, GO:0016324=IEA, GO:0015171=ISS, GO:0007596=TAS, GO:0042605=ISS, GO:0015175=TAS, GO:0006810=TAS, GO:0016021=IEA, GO:0015179=IEA, GO:0006811=TAS} amino acid transport, blood coagulation, cell differentiation, cellular amino acid metabolic process, ion transport, leukocyte migration, nervous system development, neutral amino acid transport, transmembrane transport, transport apical plasma membrane, cytosol, integral to membrane, plasma membrane L-amino acid transmembrane transporter activity, amino acid transmembrane transporter activity, neutral amino acid transmembrane transporter activity, peptide antigen binding Human SLC7A6 Reactome UniProtKB {GO:0006520=PMID:9829974, GO:0005886=Reactome:REACT_16988, GO:0006865=Reactome:REACT_13796, GO:0050900=Reactome:REACT_12051, GO:0055085=Reactome:REACT_19118, GO:0016323=GO_REF:0000039, GO:0015297=GO_REF:0000037, GO:0006461=PMID:9829974, GO:0015171=GO_REF:0000002, GO:0005887=PMID:9829974, GO:0007596=Reactome:REACT_604, GO:0006810=PMID:9829974, GO:0016021=GO_REF:0000038, GO:0006811=Reactome:REACT_19397} Q92536 Y+L amino acid transporter 2 protein 20130213 {GO:0006520=TAS, GO:0005886=TAS, GO:0006865=TAS, GO:0050900=TAS, GO:0055085=TAS, GO:0016323=IEA, GO:0015297=IEA, GO:0006461=TAS, GO:0015171=IEA, GO:0005887=TAS, GO:0007596=TAS, GO:0006810=TAS, GO:0016021=IEA, GO:0006811=TAS} amino acid transport, blood coagulation, cellular amino acid metabolic process, ion transport, leukocyte migration, protein complex assembly, transmembrane transport, transport basolateral plasma membrane, integral to membrane, integral to plasma membrane, plasma membrane amino acid transmembrane transporter activity, antiporter activity Human SLC7A6OS UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0015031=GO_REF:0000037} Q96CW6 Probable RNA polymerase II nuclear localization protein SLC7A6OS protein 20130413 {GO:0005737=IEA, GO:0005634=IEA, GO:0015031=IEA} protein transport cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 SLC7A7 Reactome UniProtKB {GO:0006520=PMID:9829974, GO:0005886=Reactome:REACT_16988, GO:0006865=Reactome:REACT_13796, GO:0050900=Reactome:REACT_12051, GO:0055085=Reactome:REACT_19118, GO:0016323=GO_REF:0000039, GO:0006461=PMID:9829974, GO:0015171=GO_REF:0000002, GO:0005887=PMID:9829974, GO:0007596=Reactome:REACT_604, GO:0006810=PMID:9829974, GO:0016021=GO_REF:0000038, GO:0006811=Reactome:REACT_19397} Q9UM01 Y+L amino acid transporter 1 protein 20130213 {GO:0006520=TAS, GO:0005886=TAS, GO:0006865=TAS, GO:0050900=TAS, GO:0055085=TAS, GO:0016323=IEA, GO:0006461=TAS, GO:0015171=IEA, GO:0005887=TAS, GO:0007596=TAS, GO:0006810=TAS, GO:0016021=IEA, GO:0006811=TAS} amino acid transport, blood coagulation, cellular amino acid metabolic process, ion transport, leukocyte migration, protein complex assembly, transmembrane transport, transport basolateral plasma membrane, integral to membrane, integral to plasma membrane, plasma membrane amino acid transmembrane transporter activity Human SLC7A8 GOC UniProtKB {GO:0005515=PMID:12716892, GO:0019534=PMID:12117417, GO:0005886=Reactome:REACT_16988, GO:0006865=Reactome:REACT_13796, GO:0050900=Reactome:REACT_12051, GO:0016323=GO_REF:0000039, GO:0005737=GO_REF:0000039, GO:0015171=Reactome:REACT_13482, GO:0042605=GO_REF:0000024, GO:0006810=PMID:10391915, GO:0015175=PMID:10391915, GO:0015179=GO_REF:0000019, GO:1901998=PMID:12117417, GO:0006811=Reactome:REACT_19397, GO:0006520=PMID:10391915, GO:0015695=PMID:12117417, GO:0009636=PMID:11311135, GO:0015101=PMID:12117417, GO:0055085=Reactome:REACT_19118, GO:0055065=PMID:11311135, GO:0015804=GO_REF:0000024, GO:0016020=GO_REF:0000002, GO:0005887=PMID:10391915, GO:0007596=Reactome:REACT_604, GO:0016021=GO_REF:0000038} Q9UHI5 Large neutral amino acids transporter small subunit 2 protein 20130413 {GO:0005515=IPI, GO:0019534=IDA, GO:0005886=TAS, GO:0006865=TAS, GO:0050900=TAS, GO:0016323=IEA, GO:0005737=IEA, GO:0015171=EXP, GO:0042605=ISS, GO:0006810=TAS, GO:0015175=TAS, GO:0015179=IEA, GO:1901998=IDA, GO:0006811=TAS, GO:0006520=TAS, GO:0015695=IDA, GO:0009636=NAS, GO:0015101=IDA, GO:0055085=TAS, GO:0055065=NAS, GO:0015804=ISS, GO:0016020=IEA, GO:0005887=TAS, GO:0007596=TAS, GO:0016021=IEA} amino acid transport, blood coagulation, cellular amino acid metabolic process, ion transport, leukocyte migration, metal ion homeostasis, neutral amino acid transport, organic cation transport, response to toxic substance, toxin transport, transmembrane transport, transport basolateral plasma membrane, cytoplasm, integral to membrane, integral to plasma membrane, membrane, plasma membrane L-amino acid transmembrane transporter activity, amino acid transmembrane transporter activity, neutral amino acid transmembrane transporter activity, organic cation transmembrane transporter activity, peptide antigen binding, protein binding, toxin transporter activity Human SLC7A9 GOC UniProtKB {GO:0006520=PMID:10471498, GO:0005886=Reactome:REACT_16988, GO:0006865=Reactome:REACT_13796, GO:0050900=Reactome:REACT_12051, GO:0055085=Reactome:REACT_19118, GO:0015804=GO_REF:0000024, GO:0006461=PMID:10799513, GO:0015171=PMID:10799513, GO:0015184=PMID:10471498, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:10471498, GO:0015811=PMID:10471498, GO:0042605=GO_REF:0000024, GO:0015175=GO_REF:0000024, GO:0006810=PMID:10799513, GO:0016021=GO_REF:0000038, GO:0006811=Reactome:REACT_19397} P82251 B(0,+)-type amino acid transporter 1 protein 20130413 {GO:0006520=TAS, GO:0005886=TAS, GO:0006865=TAS, GO:0050900=TAS, GO:0055085=TAS, GO:0015804=ISS, GO:0006461=TAS, GO:0015171=TAS, GO:0015184=TAS, GO:0007596=TAS, GO:0005887=TAS, GO:0015811=TAS, GO:0042605=ISS, GO:0015175=ISS, GO:0006810=TAS, GO:0016021=IEA, GO:0006811=TAS} L-cystine transport, amino acid transport, blood coagulation, cellular amino acid metabolic process, ion transport, leukocyte migration, neutral amino acid transport, protein complex assembly, transmembrane transport, transport integral to membrane, integral to plasma membrane, plasma membrane L-cystine transmembrane transporter activity, amino acid transmembrane transporter activity, neutral amino acid transmembrane transporter activity, peptide antigen binding Human SLC8A1 BHF-UCL UniProtKB {GO:0008092=PMID:16292983, GO:0060401=PMID:19095005, GO:0005516=GO_REF:0000037, GO:0042542=GO_REF:0000019, GO:0030018=GO_REF:0000024, GO:0060402=GO_REF:0000024, GO:0005886=PMID:19095005, GO:0009791=GO_REF:0000019, GO:0060048=GO_REF:0000019, GO:0005432=PMID:1374913, GO:0021537=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0055074=GO_REF:0000024, GO:0048747=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0016323=GO_REF:0000019, GO:0006936=PMID:1374913, GO:0007154=GO_REF:0000002, GO:0010763=GO_REF:0000019, GO:0014704=GO_REF:0000019, GO:0043197=GO_REF:0000019, GO:0033198=GO_REF:0000019, GO:0006811=Reactome:REACT_19397, GO:0001666=GO_REF:0000019, GO:0035050=GO_REF:0000019, GO:0007584=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0051481=GO_REF:0000024, GO:0005874=GO_REF:0000019, GO:0030506=PMID:17178715, GO:0010881=GO_REF:0000019, GO:0030315=GO_REF:0000019, GO:0001892=GO_REF:0000019, GO:0086064=GO_REF:0000019, GO:0055085=Reactome:REACT_19118, GO:0009749=GO_REF:0000019, GO:0042383=GO_REF:0000024, GO:0070509=PMID:1374913, GO:0003007=GO_REF:0000019, GO:0002027=GO_REF:0000024, GO:0005887=PMID:1374913, GO:0007596=Reactome:REACT_604, GO:0002026=PMID:19481548, GO:0002028=GO_REF:0000019, GO:0055119=PMID:19481548, GO:0055013=GO_REF:0000024, GO:0016021=GO_REF:0000038, GO:0071320=GO_REF:0000019} P32418 Sodium/calcium exchanger 1 protein 20120608 {GO:0008092=IDA, GO:0060401=TAS, GO:0005516=IEA, GO:0042542=IEA, GO:0030018=ISS, GO:0060402=ISS, GO:0005886=TAS, GO:0009791=IEA, GO:0060048=IEA, GO:0005432=IDA, GO:0021537=IEA, GO:0046872=IEA, GO:0055074=ISS, GO:0048747=IEA, GO:0005739=IEA, GO:0016323=IEA, GO:0006936=TAS, GO:0007154=IEA, GO:0010763=IEA, GO:0014704=IEA, GO:0043197=IEA, GO:0033198=IEA, GO:0006811=TAS, GO:0001666=IEA, GO:0035050=IEA, GO:0007584=IEA, GO:0042493=IEA, GO:0051481=ISS, GO:0005874=IEA, GO:0030506=IPI, GO:0010881=IEA, GO:0030315=IEA, GO:0001892=IEA, GO:0086064=IEA, GO:0055085=TAS, GO:0009749=IEA, GO:0042383=ISS, GO:0070509=IDA, GO:0003007=IEA, GO:0002027=ISS, GO:0005887=IDA, GO:0007596=TAS, GO:0002026=IC, GO:0002028=IEA, GO:0055119=IC, GO:0055013=ISS, GO:0016021=IEA, GO:0071320=IEA} blood coagulation, calcium ion homeostasis, calcium ion import, calcium ion transport into cytosol, cardiac muscle cell development, cardiac muscle contraction, cell communication, cell communication by electrical coupling involved in cardiac conduction, cellular response to cAMP, cytosolic calcium ion transport, embryonic heart tube development, embryonic placenta development, heart morphogenesis, ion transport, muscle contraction, muscle fiber development, positive regulation of fibroblast migration, post-embryonic development, reduction of cytosolic calcium ion concentration, regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion, regulation of heart rate, regulation of sodium ion transport, regulation of the force of heart contraction, relaxation of cardiac muscle, response to ATP, response to drug, response to glucose stimulus, response to hydrogen peroxide, response to hypoxia, response to nutrient, telencephalon development, transmembrane transport T-tubule, Z disc, basolateral plasma membrane, dendritic spine, integral to membrane, integral to plasma membrane, intercalated disc, microtubule, mitochondrion, plasma membrane, sarcolemma ankyrin binding, calcium:sodium antiporter activity, calmodulin binding, cytoskeletal protein binding, metal ion binding Human SLC8A2 Reactome UniProtKB {GO:0005516=GO_REF:0000037, GO:0007154=GO_REF:0000002, GO:0005886=Reactome:REACT_19164, GO:0007596=Reactome:REACT_604, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0005432=GO_REF:0000002, GO:0006811=Reactome:REACT_19397} Q9UPR5 Sodium/calcium exchanger 2 protein 20130301 {GO:0005516=IEA, GO:0007154=IEA, GO:0005886=TAS, GO:0007596=TAS, GO:0016021=IEA, GO:0055085=TAS, GO:0005432=IEA, GO:0006811=TAS} blood coagulation, cell communication, ion transport, transmembrane transport integral to membrane, plasma membrane calcium:sodium antiporter activity, calmodulin binding Human SLC8A3 Reactome UniProtKB {GO:0005516=GO_REF:0000037, GO:0060402=GO_REF:0000019, GO:0005886=Reactome:REACT_19164, GO:0005874=GO_REF:0000019, GO:0055085=Reactome:REACT_19118, GO:0005432=GO_REF:0000019, GO:0021537=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0042383=GO_REF:0000019, GO:0007154=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0043197=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0043025=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0071320=GO_REF:0000019, GO:0006811=Reactome:REACT_19397} P57103 Sodium/calcium exchanger 3 protein 20130301 {GO:0005516=IEA, GO:0060402=IEA, GO:0005886=TAS, GO:0005874=IEA, GO:0055085=TAS, GO:0005432=IEA, GO:0021537=IEA, GO:0005739=IEA, GO:0042383=IEA, GO:0007154=IEA, GO:0016020=IEA, GO:0043197=IEA, GO:0007596=TAS, GO:0043025=IEA, GO:0016021=IEA, GO:0071320=IEA, GO:0006811=TAS} blood coagulation, calcium ion transport into cytosol, cell communication, cellular response to cAMP, ion transport, telencephalon development, transmembrane transport dendritic spine, integral to membrane, membrane, microtubule, mitochondrion, neuronal cell body, plasma membrane, sarcolemma calcium:sodium antiporter activity, calmodulin binding Human SLC9A1 Reactome UniProtKB {GO:0005515=PMID:21392185, GO:0014070=GO_REF:0000019, GO:0005516=GO_REF:0000037, GO:0015385=PMID:11350981, GO:0005886=Reactome:REACT_120971, GO:0030307=GO_REF:0000019, GO:0005783=GO_REF:0000024, GO:0010447=PMID:97057295, GO:0044281=Reactome:REACT_111217, GO:0071468=GO_REF:0000024, GO:0051259=GO_REF:0000024, GO:0006885=PMID:97057295, GO:0071436=GO_REF:0000024, GO:0005739=GO_REF:0000019, GO:0016323=GO_REF:0000019, GO:0005737=PMID:21553168, GO:0015299=PMID:2536298, GO:0001101=PMID:97057295, GO:0045760=GO_REF:0000019, GO:0035794=GO_REF:0000019, GO:0030203=Reactome:REACT_121315, GO:0055007=GO_REF:0000019, GO:0006811=Reactome:REACT_19397, GO:0010740=GO_REF:0000019, GO:0005975=Reactome:REACT_474, GO:0042493=GO_REF:0000019, GO:0055085=Reactome:REACT_19118, GO:0002026=GO_REF:0000019, GO:0070997=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0030212=Reactome:REACT_121083, GO:0051453=PMID:15035633, GO:0016049=GO_REF:0000019, GO:0045121=GO_REF:0000019, GO:0030214=Reactome:REACT_120996, GO:0016021=PMID:8283968, GO:0048306=PMID:15035633, GO:0051930=GO_REF:0000019} P19634 Sodium/hydrogen exchanger 1 protein 20130301 {GO:0005515=IPI, GO:0014070=IEA, GO:0005516=IEA, GO:0015385=IDA, GO:0005886=TAS, GO:0030307=IEA, GO:0005783=ISS, GO:0010447=IDA, GO:0044281=TAS, GO:0071468=ISS, GO:0051259=ISS, GO:0006885=IDA, GO:0071436=ISS, GO:0005739=IEA, GO:0016323=IEA, GO:0005737=IDA, GO:0015299=TAS, GO:0001101=IDA, GO:0045760=IEA, GO:0035794=IEA, GO:0030203=TAS, GO:0055007=IEA, GO:0006811=TAS, GO:0010740=IEA, GO:0005975=TAS, GO:0042493=IEA, GO:0055085=TAS, GO:0002026=IEA, GO:0070997=IEA, GO:0005789=IEA, GO:0030212=TAS, GO:0051453=IDA, GO:0016049=IEA, GO:0045121=IEA, GO:0030214=TAS, GO:0016021=TAS, GO:0048306=IDA, GO:0051930=IEA} carbohydrate metabolic process, cardiac muscle cell differentiation, cell growth, cellular response to acidity, glycosaminoglycan metabolic process, hyaluronan catabolic process, hyaluronan metabolic process, ion transport, neuron death, positive regulation of action potential, positive regulation of cell growth, positive regulation of intracellular protein kinase cascade, positive regulation of mitochondrial membrane permeability, protein oligomerization, regulation of intracellular pH, regulation of pH, regulation of sensory perception of pain, regulation of the force of heart contraction, response to acid, response to acidity, response to drug, response to organic cyclic compound, small molecule metabolic process, sodium ion export, transmembrane transport basolateral plasma membrane, cytoplasm, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, membrane raft, mitochondrion, plasma membrane calcium-dependent protein binding, calmodulin binding, protein binding, sodium:hydrogen antiporter activity, solute:hydrogen antiporter activity Human SLC9A2 Reactome UniProtKB {GO:0015385=GO_REF:0000019, GO:0008104=GO_REF:0000019, GO:0005886=Reactome:REACT_19224, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0006885=GO_REF:0000019, GO:0006811=Reactome:REACT_19397} Q9UBY0 Sodium/hydrogen exchanger 2 protein 20130301 {GO:0015385=IEA, GO:0008104=IEA, GO:0005886=TAS, GO:0016021=IEA, GO:0055085=TAS, GO:0006885=IEA, GO:0006811=TAS} ion transport, protein localization, regulation of pH, transmembrane transport integral to membrane, plasma membrane sodium:hydrogen antiporter activity Human SLC9A3 Reactome UniProtKB {GO:0005515=PMID:19088451, GO:0005903=GO_REF:0000024, GO:0016324=GO_REF:0000019, GO:0015385=GO_REF:0000024, GO:0005886=Reactome:REACT_19224, GO:0009986=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0006885=GO_REF:0000019, GO:0006811=Reactome:REACT_19397} P48764 Sodium/hydrogen exchanger 3 protein 20130301 {GO:0005515=IPI, GO:0005903=ISS, GO:0016324=IEA, GO:0015385=ISS, GO:0005886=TAS, GO:0009986=ISS, GO:0016021=IEA, GO:0055085=TAS, GO:0006885=IEA, GO:0006811=TAS} ion transport, regulation of pH, transmembrane transport apical plasma membrane, brush border, cell surface, integral to membrane, plasma membrane protein binding, sodium:hydrogen antiporter activity Human SLC9A3R1 HPA UniProtKB {GO:0045859=GO_REF:0000024, GO:0005515=PMID:15523054, GO:0032416=GO_REF:0000019, GO:0008013=PMID:17242191, GO:0031528=GO_REF:0000024, GO:0031698=PMID:9560162, GO:0031526=GO_REF:0000019, GO:0043621=PMID:17242191, GO:0032415=PMID:9560162, GO:0043231=GO_REF:0000052, GO:0010766=GO_REF:0000019, GO:0032782=GO_REF:0000024, GO:0070373=PMID:20012548, GO:0016055=GO_REF:0000037, GO:0050780=GO_REF:0000019, GO:0030336=GO_REF:0000019, GO:0005813=GO_REF:0000052, GO:0019902=PMID:16456542, GO:0014067=GO_REF:0000024, GO:0030165=PMID:16236806, GO:0030643=GO_REF:0000019, GO:0034635=GO_REF:0000024, GO:0044062=GO_REF:0000019, GO:0051898=PMID:20736378, GO:0030036=GO_REF:0000019, GO:0008285=PMID:20736378, GO:0005886=GO_REF:0000052, GO:0030033=PMID:20937695, GO:0005634=PMID:17895247, GO:0030175=GO_REF:0000039, GO:0015629=PMID:9430655, GO:0070293=GO_REF:0000024, GO:0007191=GO_REF:0000019, GO:0071944=PMID:17895247, GO:0005737=PMID:17895247, GO:0016324=GO_REF:0000039, GO:0070851=PMID:17242191, GO:0010642=GO_REF:0000024, GO:0005102=PMID:16456542, GO:0006915=PMID:20012548, GO:0097291=PMID:18784102, GO:0001726=GO_REF:0000039, GO:0012505=GO_REF:0000039, GO:0005902=PMID:17242191, GO:0006461=PMID:9430655, GO:0016020=PMID:20736378, GO:0060158=GO_REF:0000019, GO:0034613=GO_REF:0000019, GO:0003096=GO_REF:0000019, GO:0017081=PMID:12881487} O14745 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 protein 20101115 {GO:0045859=ISS, GO:0005515=IPI, GO:0032416=IEA, GO:0008013=IPI, GO:0031528=ISS, GO:0031698=IPI, GO:0031526=IEA, GO:0043621=IDA, GO:0032415=NAS, GO:0043231=IDA, GO:0010766=IEA, GO:0032782=ISS, GO:0070373=IDA, GO:0016055=IEA, GO:0050780=IEA, GO:0030336=IEA, GO:0005813=IDA, GO:0019902=IPI, GO:0014067=ISS, GO:0030165=IPI, GO:0030643=IEA, GO:0034635=ISS, GO:0044062=IEA, GO:0051898=IMP, GO:0030036=IEA, GO:0008285=IMP, GO:0005886=IDA, GO:0030033=IMP, GO:0005634=IDA, GO:0030175=IEA, GO:0015629=TAS, GO:0070293=ISS, GO:0007191=IEA, GO:0071944=IDA, GO:0005737=IDA, GO:0016324=IEA, GO:0070851=IPI, GO:0010642=ISS, GO:0005102=IPI, GO:0006915=IDA, GO:0097291=IMP, GO:0001726=IEA, GO:0012505=IEA, GO:0005902=IDA, GO:0006461=TAS, GO:0016020=IDA, GO:0060158=IEA, GO:0034613=IEA, GO:0003096=IEA, GO:0017081=IDA} Wnt receptor signaling pathway, actin cytoskeleton organization, adenylate cyclase-activating dopamine receptor signaling pathway, apoptotic process, bile acid secretion, cellular phosphate ion homeostasis, cellular protein localization, glutathione transport, microvillus assembly, negative regulation of ERK1 and ERK2 cascade, negative regulation of cell migration, negative regulation of cell proliferation, negative regulation of phosphatidylinositol 3-kinase cascade, negative regulation of platelet-derived growth factor receptor signaling pathway, negative regulation of protein kinase B signaling cascade, negative regulation of sodium ion transport, negative regulation of sodium:hydrogen antiporter activity, phospholipase C-activating dopamine receptor signaling pathway, protein complex assembly, regulation of excretion, regulation of protein kinase activity, regulation of sodium:hydrogen antiporter activity, renal absorption, renal phosphate ion absorption, renal sodium ion transport actin cytoskeleton, apical plasma membrane, brush border membrane, cell periphery, centrosome, cytoplasm, endomembrane system, filopodium, intracellular membrane-bounded organelle, membrane, microvillus, microvillus membrane, nucleus, plasma membrane, ruffle PDZ domain binding, beta-2 adrenergic receptor binding, beta-catenin binding, chloride channel regulator activity, dopamine receptor binding, growth factor receptor binding, phosphatase binding, protein binding, protein self-association, receptor binding Human SLC9A3R2 HPA UniProtKB {GO:0005515=PMID:15523054, GO:0016324=GO_REF:0000039, GO:0005737=GO_REF:0000019, GO:0006461=PMID:9748260, GO:0008013=PMID:17242191, GO:0005886=GO_REF:0000052, GO:0019902=PMID:16456542, GO:0005102=PMID:16456542, GO:0005634=GO_REF:0000039, GO:0014067=GO_REF:0000019, GO:0008022=PMID:11786550, GO:0012505=GO_REF:0000039} Q15599 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 protein 20100326 {GO:0005515=IPI, GO:0016324=IEA, GO:0005737=IEA, GO:0006461=TAS, GO:0008013=IPI, GO:0005886=IDA, GO:0019902=IPI, GO:0005102=IPI, GO:0005634=IEA, GO:0014067=IEA, GO:0008022=IPI, GO:0012505=IEA} negative regulation of phosphatidylinositol 3-kinase cascade, protein complex assembly apical plasma membrane, cytoplasm, endomembrane system, nucleus, plasma membrane beta-catenin binding, phosphatase binding, protein C-terminus binding, protein binding, receptor binding Human SLC9A4 Reactome UniProtKB {GO:0016323=GO_REF:0000039, GO:0016324=GO_REF:0000039, GO:0015385=GO_REF:0000002, GO:0005886=Reactome:REACT_19224, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0006885=GO_REF:0000002, GO:0006811=Reactome:REACT_19397} Q6AI14 Sodium/hydrogen exchanger 4 protein 20130301 {GO:0016323=IEA, GO:0016324=IEA, GO:0015385=IEA, GO:0005886=TAS, GO:0016021=IEA, GO:0055085=TAS, GO:0006885=IEA, GO:0006811=TAS} ion transport, regulation of pH, transmembrane transport apical plasma membrane, basolateral plasma membrane, integral to membrane, plasma membrane sodium:hydrogen antiporter activity Human SLC9A5 Reactome UniProtKB {GO:0015385=GO_REF:0000002, GO:0005886=Reactome:REACT_19224, GO:0006810=PMID:9933641, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0006885=GO_REF:0000002, GO:0006811=Reactome:REACT_19397} Q14940 Sodium/hydrogen exchanger 5 protein 20130301 {GO:0015385=IEA, GO:0005886=TAS, GO:0006810=TAS, GO:0016021=IEA, GO:0055085=TAS, GO:0006885=IEA, GO:0006811=TAS} ion transport, regulation of pH, transmembrane transport, transport integral to membrane, plasma membrane sodium:hydrogen antiporter activity Human SLC9A6 Reactome UniProtKB {GO:0005739=PMID:11940519, GO:0015385=GO_REF:0000002, GO:0005886=PMID:11940519, GO:0031901=Reactome:REACT_19253, GO:0006810=PMID:9507001, GO:0005789=PMID:11641397, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0055038=PMID:11940519, GO:0006885=GO_REF:0000002, GO:0006811=Reactome:REACT_19397} Q92581 Sodium/hydrogen exchanger 6 protein 20130301 {GO:0005739=IDA, GO:0015385=IEA, GO:0005886=IDA, GO:0031901=TAS, GO:0006810=TAS, GO:0005789=IDA, GO:0016021=IEA, GO:0055085=TAS, GO:0055038=IDA, GO:0006885=IEA, GO:0006811=TAS} ion transport, regulation of pH, transmembrane transport, transport early endosome membrane, endoplasmic reticulum membrane, integral to membrane, mitochondrion, plasma membrane, recycling endosome membrane sodium:hydrogen antiporter activity Human SLC9A7 Reactome UniProtKB {GO:0005515=PMID:15840657, GO:0005802=PMID:11279194, GO:0015386=PMID:11279194, GO:0015385=PMID:11279194, GO:0000139=Reactome:REACT_19218, GO:0016021=PMID:11279194, GO:0055085=Reactome:REACT_19118, GO:0055038=PMID:15840657, GO:0006885=PMID:11279194, GO:0042803=PMID:11279194, GO:0006811=Reactome:REACT_19397} Q96T83 Sodium/hydrogen exchanger 7 protein 20130301 {GO:0005515=IPI, GO:0005802=IDA, GO:0015386=IDA, GO:0015385=IDA, GO:0000139=TAS, GO:0016021=IDA, GO:0055085=TAS, GO:0055038=IDA, GO:0006885=IDA, GO:0042803=TAS, GO:0006811=TAS} ion transport, regulation of pH, transmembrane transport Golgi membrane, integral to membrane, recycling endosome membrane, trans-Golgi network potassium:hydrogen antiporter activity, protein binding, protein homodimerization activity, sodium:hydrogen antiporter activity Human SLC9A8 Reactome UniProtKB {GO:0015386=GO_REF:0000019, GO:0015385=GO_REF:0000019, GO:0005794=GO_REF:0000019, GO:0000139=Reactome:REACT_19218, GO:0051453=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_19118, GO:0006811=Reactome:REACT_19397} Q9Y2E8 Sodium/hydrogen exchanger 8 protein 20130301 {GO:0015386=IEA, GO:0015385=IEA, GO:0005794=IEA, GO:0000139=TAS, GO:0051453=IEA, GO:0016021=IEA, GO:0055085=TAS, GO:0006811=TAS} ion transport, regulation of intracellular pH, transmembrane transport Golgi apparatus, Golgi membrane, integral to membrane potassium:hydrogen antiporter activity, sodium:hydrogen antiporter activity Human SLC9B2 Reactome UniProtKB {GO:0034220=Reactome:REACT_25300, GO:0015299=GO_REF:0000002, GO:0005743=Reactome:REACT_160252, GO:0016491=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0006814=GO_REF:0000037, GO:0055085=Reactome:REACT_15518} Q86UD5 Mitochondrial sodium/hydrogen exchanger 9B2 protein 20130301 {GO:0034220=TAS, GO:0015299=IEA, GO:0005743=TAS, GO:0016491=IEA, GO:0016021=IEA, GO:0006814=IEA, GO:0055085=TAS} ion transmembrane transport, sodium ion transport, transmembrane transport integral to membrane, mitochondrial inner membrane oxidoreductase activity, solute:hydrogen antiporter activity Human SLCO1A2 Reactome UniProtKB {GO:0005215=GO_REF:0000002, GO:0005886=Reactome:REACT_10072, GO:0016020=GO_REF:0000002, GO:0015721=Reactome:REACT_11042, GO:0015711=PMID:9007731, GO:0043252=Reactome:REACT_23988, GO:0008206=Reactome:REACT_11040, GO:0008514=PMID:9007731, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_19118} P46721 Solute carrier organic anion transporter family member 1A2 protein 20130301 {GO:0005215=IEA, GO:0005886=TAS, GO:0016020=IEA, GO:0015721=TAS, GO:0015711=TAS, GO:0043252=TAS, GO:0008206=TAS, GO:0008514=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0055085=TAS} bile acid and bile salt transport, bile acid metabolic process, organic anion transport, small molecule metabolic process, sodium-independent organic anion transport, transmembrane transport integral to membrane, membrane, plasma membrane organic anion transmembrane transporter activity, transporter activity Human SLCO1B1 Reactome UniProtKB {GO:0016323=GO_REF:0000039, GO:0005886=Reactome:REACT_23913, GO:0016020=PMID:10358072, GO:0015347=PMID:10358072, GO:0005887=PMID:10358072, GO:0015721=Reactome:REACT_11042, GO:0015711=PMID:10358072, GO:0043252=Reactome:REACT_23988, GO:0008206=Reactome:REACT_11040, GO:0044281=Reactome:REACT_111217, GO:0055085=Reactome:REACT_19118} Q9Y6L6 Solute carrier organic anion transporter family member 1B1 protein 20130301 {GO:0016323=IEA, GO:0005886=TAS, GO:0016020=TAS, GO:0015347=TAS, GO:0005887=TAS, GO:0015721=TAS, GO:0015711=TAS, GO:0043252=TAS, GO:0008206=TAS, GO:0044281=TAS, GO:0055085=TAS} bile acid and bile salt transport, bile acid metabolic process, organic anion transport, small molecule metabolic process, sodium-independent organic anion transport, transmembrane transport basolateral plasma membrane, integral to plasma membrane, membrane, plasma membrane sodium-independent organic anion transmembrane transporter activity Human SLCO1B3 HPA UniProtKB {GO:0005215=GO_REF:0000002, GO:0005886=Reactome:REACT_10124, GO:0043252=Reactome:REACT_23988, GO:0044281=Reactome:REACT_111217, GO:0055085=Reactome:REACT_19118, GO:0016323=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0016020=GO_REF:0000002, GO:0005887=PMID:10779507, GO:0015721=Reactome:REACT_11042, GO:0015711=PMID:10779507, GO:0008514=PMID:10779507, GO:0008206=Reactome:REACT_11040} Q9NPD5 Solute carrier organic anion transporter family member 1B3 protein 20100326 {GO:0005215=IEA, GO:0005886=TAS, GO:0043252=TAS, GO:0044281=TAS, GO:0055085=TAS, GO:0016323=IEA, GO:0005737=IDA, GO:0016020=IEA, GO:0005887=TAS, GO:0015721=TAS, GO:0015711=TAS, GO:0008514=TAS, GO:0008206=TAS} bile acid and bile salt transport, bile acid metabolic process, organic anion transport, small molecule metabolic process, sodium-independent organic anion transport, transmembrane transport basolateral plasma membrane, cytoplasm, integral to plasma membrane, membrane, plasma membrane organic anion transmembrane transporter activity, transporter activity Human SLCO1C1 Reactome UniProtKB {GO:0005215=GO_REF:0000002, GO:0005886=Reactome:REACT_23913, GO:0043252=Reactome:REACT_23988, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_19118} Q9NYB5 Solute carrier organic anion transporter family member 1C1 protein 20130301 {GO:0005215=IEA, GO:0005886=TAS, GO:0043252=TAS, GO:0016021=IEA, GO:0055085=TAS} sodium-independent organic anion transport, transmembrane transport integral to membrane, plasma membrane transporter activity Human SLCO2B1 Reactome UniProtKB {GO:0005215=GO_REF:0000002, GO:0016324=GO_REF:0000019, GO:0005886=Reactome:REACT_23829, GO:0016020=GO_REF:0000002, GO:0015347=PMID:18501590, GO:0043252=Reactome:REACT_23988, GO:0008514=PMID:18501590, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_19118} O94956 Solute carrier organic anion transporter family member 2B1 protein 20130301 {GO:0005215=IEA, GO:0016324=IEA, GO:0005886=TAS, GO:0016020=IEA, GO:0015347=IDA, GO:0043252=TAS, GO:0008514=IDA, GO:0016021=IEA, GO:0055085=TAS} sodium-independent organic anion transport, transmembrane transport apical plasma membrane, integral to membrane, membrane, plasma membrane organic anion transmembrane transporter activity, sodium-independent organic anion transmembrane transporter activity, transporter activity Human SLCO3A1 Reactome UniProtKB {GO:0005215=GO_REF:0000002, GO:0005886=Reactome:REACT_23822, GO:0016020=GO_REF:0000002, GO:0043252=Reactome:REACT_23988, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_19118} Q9UIG8 Solute carrier organic anion transporter family member 3A1 protein 20130301 {GO:0005215=IEA, GO:0005886=TAS, GO:0016020=IEA, GO:0043252=TAS, GO:0016021=IEA, GO:0055085=TAS} sodium-independent organic anion transport, transmembrane transport integral to membrane, membrane, plasma membrane transporter activity Human SLCO4A1 Reactome UniProtKB {GO:0005215=GO_REF:0000002, GO:0005886=Reactome:REACT_23913, GO:0016020=GO_REF:0000002, GO:0043252=Reactome:REACT_23988, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_19118} Q96BD0 Solute carrier organic anion transporter family member 4A1 protein 20130301 {GO:0005215=IEA, GO:0005886=TAS, GO:0016020=IEA, GO:0043252=TAS, GO:0016021=IEA, GO:0055085=TAS} sodium-independent organic anion transport, transmembrane transport integral to membrane, membrane, plasma membrane transporter activity Human SLCO5A1 UniProtKB UniProtKB {GO:0005215=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q9H2Y9 Solute carrier organic anion transporter family member 5A1 protein 20130413 {GO:0005215=IEA, GO:0005886=IEA, GO:0016020=IEA, GO:0016021=IEA} integral to membrane, membrane, plasma membrane transporter activity Human UniProtKB-SubCell:SL-0039 SLFN11 LIFEdb UniProtKB {GO:0051607=PMID:23000900, GO:0000049=PMID:23000900, GO:0005634=GO_REF:0000054, GO:0005524=GO_REF:0000037} Q7Z7L1 Schlafen family member 11 protein 20100607 {GO:0051607=IMP, GO:0000049=IDA, GO:0005634=IDA, GO:0005524=IEA} defense response to virus nucleus ATP binding, tRNA binding Human SLFN12 InterPro UniProtKB {GO:0005524=GO_REF:0000002} Q8IYM2 Schlafen family member 12 protein 20130413 {GO:0005524=IEA} ATP binding Human InterPro:IPR007421 SLFN12L UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000002} Q6IEE8 Schlafen family member 12-like protein 20130413 {GO:0016021=IEA, GO:0005524=IEA} integral to membrane ATP binding Human UniProtKB-KW:KW-0812 SLFN5 ENSEMBL UniProtKB {GO:0005634=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q08AF3 Schlafen family member 5 protein 20130413 {GO:0005634=IEA, GO:0005524=IEA, GO:0030154=IEA} cell differentiation nucleus ATP binding Human Ensembl:ENSMUSP00000064819 SLFNL1 UniProtKB UniProtKB {GO:0005524=GO_REF:0000037} Q499Z3 Schlafen-like protein 1 protein 20130413 {GO:0005524=IEA} ATP binding Human UniProtKB-KW:KW-0067 SLIRP HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q9GZT3 SRA stem-loop-interacting RNA-binding protein, mitochondrial protein 20111111 {GO:0005739=IDA, GO:0006355=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0005634=IEA, GO:0003676=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent mitochondrion, nucleus RNA binding, nucleic acid binding, nucleotide binding Human SLIT1 InterPro UniProtKB {GO:0031290=GO_REF:0000019, GO:0051964=GO_REF:0000024, GO:0021510=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0050919=PMID:11748139, GO:0048843=GO_REF:0000019, GO:0043395=GO_REF:0000019, GO:0048846=PMID:16840550, GO:0005615=PMID:9813312, GO:0048495=PMID:15207848, GO:0033563=GO_REF:0000019, GO:0048853=PMID:9813312, GO:0021834=PMID:11748139, GO:0005737=GO_REF:0000052, GO:0008045=PMID:16162649, GO:0040023=GO_REF:0000019, GO:0007411=Reactome:REACT_18266} Q5T0V0 Slit homolog 1 protein protein 20130413 {GO:0031290=IEA, GO:0051964=ISS, GO:0021510=IEA, GO:0005509=IEA, GO:0050919=IDA, GO:0048843=IEA, GO:0043395=IEA, GO:0048846=IDA, GO:0005615=NAS, GO:0048495=IPI, GO:0033563=IEA, GO:0048853=NAS, GO:0021834=IDA, GO:0005737=IDA, GO:0008045=IMP, GO:0040023=IEA, GO:0007411=TAS} axon extension involved in axon guidance, axon guidance, chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration, dorsal/ventral axon guidance, establishment of nucleus localization, forebrain morphogenesis, motor neuron axon guidance, negative chemotaxis, negative regulation of axon extension involved in axon guidance, negative regulation of synapse assembly, retinal ganglion cell axon guidance, spinal cord development cytoplasm, extracellular space Roundabout binding, calcium ion binding, heparan sulfate proteoglycan binding Human InterPro:IPR001881|InterPro:IPR018097 SLIT2 BHF-UCL UniProtKB {GO:0001656=GO_REF:0000019, GO:0005515=PMID:10102268, GO:0001657=PMID:15130495, GO:0071676=PMID:16439689, GO:0030308=PMID:18829537, GO:0090260=PMID:17062560, GO:0048846=PMID:16840550, GO:0048495=PMID:10102268, GO:0005615=PMID:16439689, GO:0071672=PMID:16439689, GO:0042803=PMID:19498462, GO:0016337=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0070100=PMID:18829537, GO:0030837=PMID:19759280, GO:0021972=PMID:10975526, GO:0030336=PMID:19005219, GO:0005509=PMID:9813312, GO:0043394=PMID:11375980, GO:0060763=GO_REF:0000019, GO:0061364=PMID:18566128, GO:0035385=PMID:10102268, GO:0021836=PMID:15207848, GO:0001701=GO_REF:0000019, GO:0021834=PMID:11748139, GO:0051414=PMID:18566128, GO:0010596=PMID:18345009, GO:0045499=GO_REF:0000019, GO:0008045=PMID:10102268, GO:0043237=PMID:10102268, GO:0090024=PMID:19759280, GO:0050772=PMID:10197527, GO:0090027=GO_REF:0000024, GO:0031290=PMID:19498462, GO:0008285=GO_REF:0000019, GO:0005886=Reactome:REACT_19396, GO:0090288=PMID:16439689, GO:0002042=PMID:19351956, GO:0050929=PMID:10197527, GO:0014912=PMID:16439689, GO:0033563=GO_REF:0000019, GO:0032870=PMID:18566128, GO:0005737=PMID:18566128, GO:0010593=PMID:16439689, GO:0008201=PMID:17062560, GO:0043065=PMID:18566128, GO:0051058=PMID:16439689, GO:0050919=PMID:19005219, GO:0005576=Reactome:REACT_19284, GO:0016020=PMID:16439689, GO:0071504=PMID:17062560, GO:0002689=PMID:11309622, GO:0010629=GO_REF:0000019, GO:0001933=PMID:18345009, GO:0048754=PMID:18345009, GO:0005095=PMID:16439689, GO:0043116=PMID:18345009} O94813 Slit homolog 2 protein protein 20100219 {GO:0001656=IEA, GO:0005515=IPI, GO:0001657=IMP, GO:0071676=IDA, GO:0030308=IMP, GO:0090260=IDA, GO:0048846=IDA, GO:0048495=IPI, GO:0005615=IDA, GO:0071672=IDA, GO:0042803=IDA, GO:0016337=IEA, GO:0007411=TAS, GO:0070100=IMP, GO:0030837=IDA, GO:0021972=IMP, GO:0030336=IDA, GO:0005509=NAS, GO:0043394=IPI, GO:0060763=IEA, GO:0061364=IEP, GO:0035385=IC, GO:0021836=IDA, GO:0001701=IEA, GO:0021834=IDA, GO:0051414=IEP, GO:0010596=IDA, GO:0045499=IEA, GO:0008045=IDA, GO:0043237=IDA, GO:0090024=IDA, GO:0050772=TAS, GO:0090027=ISS, GO:0031290=IDA, GO:0008285=IEA, GO:0005886=TAS, GO:0090288=IDA, GO:0002042=IMP, GO:0050929=IDA, GO:0014912=IDA, GO:0033563=IEA, GO:0032870=IEP, GO:0005737=IDA, GO:0010593=IDA, GO:0008201=IDA, GO:0043065=IMP, GO:0051058=IDA, GO:0050919=IMP, GO:0005576=TAS, GO:0016020=NAS, GO:0071504=IDA, GO:0002689=IDA, GO:0010629=IEA, GO:0001933=IDA, GO:0048754=IDA, GO:0005095=IDA, GO:0043116=IDA} Roundabout signaling pathway, apoptotic process involved in luteolysis, axon extension involved in axon guidance, axon guidance, branching morphogenesis of an epithelial tube, cell migration involved in sprouting angiogenesis, cell-cell adhesion, cellular response to heparin, cellular response to hormone stimulus, chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration, chemorepulsion involved in postnatal olfactory bulb interneuron migration, corticospinal neuron axon guidance through spinal cord, dorsal/ventral axon guidance, in utero embryonic development, induction of negative chemotaxis, mammary duct terminal end bud growth, metanephros development, motor neuron axon guidance, negative chemotaxis, negative regulation of actin filament polymerization, negative regulation of cell growth, negative regulation of cell migration, negative regulation of cell proliferation, negative regulation of cellular response to growth factor stimulus, negative regulation of chemokine-mediated signaling pathway, negative regulation of endothelial cell migration, negative regulation of gene expression, negative regulation of lamellipodium assembly, negative regulation of leukocyte chemotaxis, negative regulation of monocyte chemotaxis, negative regulation of mononuclear cell migration, negative regulation of neutrophil chemotaxis, negative regulation of protein phosphorylation, negative regulation of retinal ganglion cell axon guidance, negative regulation of small GTPase mediated signal transduction, negative regulation of smooth muscle cell chemotaxis, negative regulation of smooth muscle cell migration, negative regulation of vascular permeability, positive regulation of apoptotic process, positive regulation of axonogenesis, response to cortisol stimulus, retinal ganglion cell axon guidance, ureteric bud development cytoplasm, extracellular region, extracellular space, membrane, plasma membrane GTPase inhibitor activity, Roundabout binding, calcium ion binding, chemorepellent activity, heparin binding, laminin-1 binding, protein binding, protein homodimerization activity, proteoglycan binding Human SLIT3 BHF-UCL UniProtKB {GO:0030308=PMID:18829537, GO:0008285=GO_REF:0000019, GO:0005509=PMID:9813312, GO:0050919=PMID:11748139, GO:0005576=GO_REF:0000038, GO:0061364=PMID:18566128, GO:0048846=PMID:16840550, GO:0035385=PMID:18829537, GO:0048495=PMID:15207848, GO:0005615=PMID:19741192, GO:0032870=PMID:18566128, GO:0051414=PMID:18566128, GO:0021834=PMID:11748139, GO:0005739=PMID:11443047, GO:0070100=PMID:18829537, GO:0007411=Reactome:REACT_18266, GO:0010629=GO_REF:0000019, GO:0009887=GO_REF:0000019} O75094 Slit homolog 3 protein protein 20100421 {GO:0030308=IMP, GO:0008285=IEA, GO:0005509=NAS, GO:0050919=IDA, GO:0005576=IEA, GO:0061364=IEP, GO:0048846=IDA, GO:0035385=IMP, GO:0048495=IPI, GO:0005615=IDA, GO:0032870=IEP, GO:0051414=IEP, GO:0021834=IDA, GO:0005739=NAS, GO:0070100=IMP, GO:0007411=TAS, GO:0010629=IEA, GO:0009887=IEA} Roundabout signaling pathway, apoptotic process involved in luteolysis, axon extension involved in axon guidance, axon guidance, cellular response to hormone stimulus, chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration, negative chemotaxis, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of chemokine-mediated signaling pathway, negative regulation of gene expression, organ morphogenesis, response to cortisol stimulus extracellular region, extracellular space, mitochondrion Roundabout binding, calcium ion binding Human SLITRK1 ENSEMBL UniProtKB {GO:0007409=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q96PX8 SLIT and NTRK-like protein 1 protein 20130413 {GO:0007409=IEA, GO:0016021=IEA} axonogenesis integral to membrane Human Ensembl:ENSMUSP00000097897 SLITRK3 ENSEMBL UniProtKB {GO:0016021=GO_REF:0000037, GO:0007409=GO_REF:0000019} O94933 SLIT and NTRK-like protein 3 protein 20130413 {GO:0016021=IEA, GO:0007409=IEA} axonogenesis integral to membrane Human Ensembl:ENSMUSP00000088561 SLK HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0046777=PMID:18239682, GO:0005886=GO_REF:0000052, GO:0004674=PMID:18239682, GO:0006915=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0042803=PMID:18239682} Q9H2G2 STE20-like serine/threonine-protein kinase protein 20090616 {GO:0005737=IDA, GO:0046777=IDA, GO:0005886=IDA, GO:0004674=IDA, GO:0006915=IEA, GO:0005524=IEA, GO:0042803=IDA} apoptotic process, protein autophosphorylation cytoplasm, plasma membrane ATP binding, protein homodimerization activity, protein serine/threonine kinase activity Human SLMAP PINC UniProtKB {GO:0042383=GO_REF:0000039, GO:0006936=PMID:9405447, GO:0005815=GO_REF:0000039, GO:0005887=PMID:9405447, GO:0006457=GO_REF:0000002, GO:0016272=GO_REF:0000002, GO:0016021=GO_REF:0000019, GO:0051082=GO_REF:0000002, GO:0005790=PMID:9405447} Q14BN4 Sarcolemmal membrane-associated protein protein 20061107 {GO:0042383=IEA, GO:0006936=TAS, GO:0005815=IEA, GO:0005887=TAS, GO:0006457=IEA, GO:0016272=IEA, GO:0016021=IEA, GO:0051082=IEA, GO:0005790=TAS} muscle contraction, protein folding integral to membrane, integral to plasma membrane, microtubule organizing center, prefoldin complex, sarcolemma, smooth endoplasmic reticulum unfolded protein binding Human SLMO2 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019} Q9Y3B1 Protein slowmo homolog 2 protein 20130413 {GO:0005739=IEA} mitochondrion Human Ensembl:ENSMUSP00000016401 SLN BHF-UCL UniProtKB {GO:0004857=PMID:12032137, GO:1901020=PMID:12032137, GO:1901877=PMID:12032137, GO:0033017=GO_REF:0000039, GO:1901881=PMID:12032137, GO:0043086=PMID:12032137, GO:0043242=PMID:12032137, GO:0090281=PMID:12032137, GO:0016529=PMID:9575189, GO:0051924=GO_REF:0000024, GO:0051117=PMID:12032137, GO:0006816=PMID:9367679, GO:0016021=PMID:9367679} O00631 Sarcolipin protein 20130206 {GO:0004857=ISS, GO:1901020=ISS, GO:1901877=ISS, GO:0033017=IEA, GO:1901881=ISS, GO:0043086=ISS, GO:0043242=ISS, GO:0090281=ISS, GO:0016529=IDA, GO:0051924=ISS, GO:0051117=ISS, GO:0006816=NAS, GO:0016021=NAS} calcium ion transport, negative regulation of calcium ion binding, negative regulation of calcium ion import, negative regulation of calcium ion transmembrane transporter activity, negative regulation of catalytic activity, negative regulation of protein complex disassembly, positive regulation of protein depolymerization, regulation of calcium ion transport integral to membrane, sarcoplasmic reticulum, sarcoplasmic reticulum membrane ATPase binding, enzyme inhibitor activity Human UniProtKB:P42532 SLPI GOC UniProtKB {GO:0010951=PMID:3485543, GO:0005515=PMID:19333378, GO:0032091=PMID:19333378, GO:0004866=PMID:3485543, GO:0004867=GO_REF:0000037, GO:0005576=GO_REF:0000039, GO:0019899=PMID:19333378, GO:0045071=PMID:19333378} P03973 Antileukoproteinase protein 20130413 {GO:0010951=TAS, GO:0005515=IPI, GO:0032091=IDA, GO:0004866=TAS, GO:0004867=IEA, GO:0005576=IEA, GO:0019899=IPI, GO:0045071=IDA} negative regulation of endopeptidase activity, negative regulation of protein binding, negative regulation of viral genome replication extracellular region endopeptidase inhibitor activity, enzyme binding, protein binding, serine-type endopeptidase inhibitor activity Human SLTM HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q9NWH9 SAFB-like transcription modulator protein 20110516 {GO:0006355=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0006915=IEA, GO:0005634=IDA, GO:0003676=IEA, GO:0006351=IEA} apoptotic process, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus, nucleus RNA binding, nucleic acid binding, nucleotide binding NOT Human SLU7 HPA UniProtKB {GO:0030628=PMID:15728250, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0033554=PMID:19369195, GO:0003676=GO_REF:0000002, GO:0071013=PMID:11991638, GO:0006886=PMID:19369195, GO:0000389=PMID:15728250, GO:0043231=GO_REF:0000052, GO:0000386=PMID:10197984, GO:0005737=PMID:19369195, GO:0016607=PMID:15728250, GO:0000398=PMID:11991638, GO:0000375=PMID:10197984, GO:0000380=PMID:15728250, GO:0030532=PMID:15181151, GO:0005681=PMID:10197984, GO:0008270=PMID:15181151} O95391 Pre-mRNA-splicing factor SLU7 protein 20110516 {GO:0030628=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0033554=IDA, GO:0003676=IEA, GO:0071013=IDA, GO:0006886=IDA, GO:0000389=IDA, GO:0043231=IDA, GO:0000386=IDA, GO:0005737=IDA, GO:0016607=IDA, GO:0000398=IC, GO:0000375=IDA, GO:0000380=IDA, GO:0030532=IDA, GO:0005681=IDA, GO:0008270=IDA} RNA splicing, via transesterification reactions, alternative mRNA splicing, via spliceosome, cellular response to stress, intracellular protein transport, mRNA 3'-splice site recognition, mRNA splicing, via spliceosome catalytic step 2 spliceosome, cytoplasm, intracellular membrane-bounded organelle, nuclear speck, nucleolus, nucleus, small nuclear ribonucleoprotein complex, spliceosomal complex nucleic acid binding, pre-mRNA 3'-splice site binding, second spliceosomal transesterification activity, zinc ion binding Human SLX1A UniProtKB UniProtKB {GO:0005515=PMID:19595721, GO:0006281=PMID:19595721, GO:0000724=PMID:19595721, GO:0008821=PMID:19596236, GO:0010792=PMID:19595721, GO:0017108=PMID:19596235, GO:0033557=PMID:19596235, GO:0046872=GO_REF:0000037} Q9BQ83 Structure-specific endonuclease subunit SLX1 protein 20090811 {GO:0005515=IPI, GO:0006281=IMP, GO:0000724=IMP, GO:0008821=IDA, GO:0010792=IMP, GO:0017108=IDA, GO:0033557=IDA, GO:0046872=IEA} DNA double-strand break processing involved in repair via single-strand annealing, DNA repair, double-strand break repair via homologous recombination Slx1-Slx4 complex 5'-flap endonuclease activity, crossover junction endodeoxyribonuclease activity, metal ion binding, protein binding Human SLX1B null null {} null null null null {} null null null SLX4 GOC UniProtKB {GO:0005515=PMID:19596236, GO:0000790=PMID:19596235, GO:0048476=PMID:19595721, GO:0008821=PMID:19595721, GO:0010792=PMID:19595721, GO:0043085=PMID:19596235, GO:0033557=PMID:19596236, GO:0006281=PMID:19595722, GO:0000724=PMID:19595721, GO:0070522=PMID:19595721, GO:0048257=PMID:19595721, GO:0017108=PMID:19596236, GO:0006289=PMID:19596236, GO:0008047=PMID:19596235, GO:0000784=PMID:19596235} Q8IY92 Structure-specific endonuclease subunit SLX4 protein 20130413 {GO:0005515=IPI, GO:0000790=IDA, GO:0048476=IDA, GO:0008821=IDA, GO:0010792=IMP, GO:0043085=IDA, GO:0033557=IDA, GO:0006281=IMP, GO:0000724=IMP, GO:0070522=IDA, GO:0048257=IDA, GO:0017108=IDA, GO:0006289=IMP, GO:0008047=IDA, GO:0000784=IDA} DNA double-strand break processing involved in repair via single-strand annealing, DNA repair, double-strand break repair via homologous recombination, nucleotide-excision repair, positive regulation of catalytic activity ERCC4-ERCC1 complex, Holliday junction resolvase complex, Slx1-Slx4 complex, nuclear chromatin, nuclear chromosome, telomeric region 3'-flap endonuclease activity, 5'-flap endonuclease activity, crossover junction endodeoxyribonuclease activity, enzyme activator activity, protein binding Human SMAD1 BHF-UCL UniProtKB {GO:0005515=PMID:11278251, GO:0071773=GO_REF:0000024, GO:0001657=GO_REF:0000019, GO:0003700=PMID:9389648, GO:0051216=GO_REF:0000019, GO:0001710=GO_REF:0000019, GO:0042802=PMID:9111321, GO:0005622=PMID:10647776, GO:0009880=GO_REF:0000024, GO:0000165=GO_REF:0000019, GO:0007179=PMID:8663601, GO:0019901=PMID:12874272, GO:0007276=GO_REF:0000019, GO:0010243=GO_REF:0000019, GO:0030509=PMID:19664780, GO:0000979=GO_REF:0000019, GO:0060038=GO_REF:0000019, GO:0060348=GO_REF:0000019, GO:0007183=PMID:9111321, GO:0050775=GO_REF:0000019, GO:0042060=GO_REF:0000019, GO:0005654=Reactome:REACT_12067, GO:0030618=PMID:19018011, GO:0008285=GO_REF:0000019, GO:0005637=PMID:15647271, GO:0005634=PMID:9389648, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_12080, GO:0005737=PMID:9389648, GO:0006954=GO_REF:0000019, GO:0045944=PMID:19664780, GO:0031053=PMID:19018011, GO:1901522=GO_REF:0000024, GO:0005667=GO_REF:0000019, GO:0001822=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0002051=GO_REF:0000019, GO:0070410=PMID:9111321, GO:0070411=PMID:9436979, GO:0042592=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0045669=GO_REF:0000019, GO:0007165=PMID:9759503, GO:0071407=GO_REF:0000019, GO:0061036=GO_REF:0000019, GO:0030901=GO_REF:0000019, GO:0006468=GO_REF:0000019, GO:0005057=PMID:8653785, GO:0016021=PMID:8663601, GO:0030902=GO_REF:0000019} Q15797 Mothers against decapentaplegic homolog 1 protein 20120708 {GO:0005515=IPI, GO:0071773=ISS, GO:0001657=IEA, GO:0003700=IDA, GO:0051216=IEA, GO:0001710=IEA, GO:0042802=IPI, GO:0005622=NAS, GO:0009880=ISS, GO:0000165=IEA, GO:0007179=NAS, GO:0019901=IPI, GO:0007276=IEA, GO:0010243=IEA, GO:0030509=IMP, GO:0000979=IEA, GO:0060038=IEA, GO:0060348=IEA, GO:0007183=IDA, GO:0050775=IEA, GO:0042060=IEA, GO:0005654=TAS, GO:0030618=TAS, GO:0008285=IEA, GO:0005637=IDA, GO:0005634=IDA, GO:0046872=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0006954=IEA, GO:0045944=IC, GO:0031053=TAS, GO:1901522=ISS, GO:0005667=IEA, GO:0001822=IEA, GO:0042493=IEA, GO:0002051=IEA, GO:0070410=IPI, GO:0070411=IPI, GO:0042592=IEA, GO:0006351=IEA, GO:0045669=IEA, GO:0007165=NAS, GO:0071407=IEA, GO:0061036=IEA, GO:0030901=IEA, GO:0006468=IEA, GO:0005057=NAS, GO:0016021=NAS, GO:0030902=IEA} BMP signaling pathway, MAPK cascade, SMAD protein complex assembly, bone development, cardiac muscle cell proliferation, cartilage development, cellular response to BMP stimulus, cellular response to organic cyclic compound, embryonic pattern specification, gamete generation, hindbrain development, homeostatic process, inflammatory response, kidney development, mesodermal cell fate commitment, midbrain development, negative regulation of cell proliferation, osteoblast fate commitment, positive regulation of cartilage development, positive regulation of dendrite morphogenesis, positive regulation of osteoblast differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus, primary miRNA processing, protein phosphorylation, response to drug, response to organic nitrogen, signal transduction, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, ureteric bud development, wound healing cytoplasm, cytosol, integral to membrane, intracellular, nuclear inner membrane, nucleoplasm, nucleus, transcription factor complex I-SMAD binding, RNA polymerase II core promoter sequence-specific DNA binding, co-SMAD binding, identical protein binding, metal ion binding, protein binding, protein kinase binding, receptor signaling protein activity, sequence-specific DNA binding transcription factor activity, transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity Human UniProtKB:Q9HCE7 SMAD2 BHF-UCL UniProtKB {GO:0005515=PMID:19135894, GO:0001657=GO_REF:0000019, GO:0010467=Reactome:REACT_71, GO:0003700=PMID:17438144, GO:0006367=Reactome:REACT_12627, GO:0046332=PMID:11160896, GO:0009791=GO_REF:0000019, GO:1900224=PMID:17239842, GO:0048701=GO_REF:0000019, GO:0003690=GO_REF:0000024, GO:0048589=GO_REF:0000019, GO:0007179=PMID:8980228, GO:0017015=PMID:14555988, GO:0031625=PMID:19122240, GO:0001707=GO_REF:0000024, GO:0019902=PMID:16751101, GO:0071141=PMID:18832382, GO:0000122=Reactome:REACT_121111, GO:0032924=PMID:15150278, GO:0060039=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0005160=PMID:9311995, GO:0007182=PMID:16806156, GO:0007183=PMID:9111321, GO:0045165=GO_REF:0000024, GO:0038092=PMID:15150278, GO:0048340=GO_REF:0000024, GO:0005654=Reactome:REACT_121396, GO:0045893=GO_REF:0000024, GO:0030073=GO_REF:0000019, GO:0045892=PMID:14555988, GO:0008134=PMID:9702198, GO:0030618=PMID:9256479, GO:0007369=PMID:19018011, GO:0008285=GO_REF:0000019, GO:0030324=GO_REF:0000019, GO:0010718=GO_REF:0000024, GO:0005634=PMID:8980228, GO:0009952=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_150345, GO:0035556=GO_REF:0000024, GO:0030513=PMID:19366699, GO:0005737=PMID:9389648, GO:0035265=GO_REF:0000019, GO:0045944=Reactome:REACT_120734, GO:0031053=PMID:19018011, GO:0060021=GO_REF:0000024, GO:0033613=PMID:11160896, GO:0030512=Reactome:REACT_120727, GO:0005667=PMID:17438144, GO:0070410=PMID:9311995, GO:0070411=PMID:9256479, GO:0051098=GO_REF:0000024, GO:0070412=PMID:9311995, GO:0007352=PMID:9436979, GO:0003677=PMID:9389648, GO:0006351=Reactome:REACT_121061, GO:0032444=PMID:9389648, GO:0009749=GO_REF:0000019, GO:0034713=PMID:8980228, GO:0031016=GO_REF:0000019, GO:0007492=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0048617=GO_REF:0000019, GO:0070723=PMID:17878231} Q15796 Mothers against decapentaplegic homolog 2 protein 20120517 {GO:0005515=IPI, GO:0001657=IEA, GO:0010467=TAS, GO:0003700=IDA, GO:0006367=TAS, GO:0046332=IPI, GO:0009791=IEA, GO:1900224=IMP, GO:0048701=IEA, GO:0003690=ISS, GO:0048589=IEA, GO:0007179=IMP, GO:0017015=IMP, GO:0031625=IPI, GO:0001707=ISS, GO:0019902=IPI, GO:0071141=IDA, GO:0000122=TAS, GO:0032924=IMP, GO:0060039=IEA, GO:0001701=IEA, GO:0005160=IPI, GO:0007182=IDA, GO:0007183=IDA, GO:0045165=ISS, GO:0038092=IMP, GO:0048340=ISS, GO:0005654=TAS, GO:0045893=ISS, GO:0030073=IEA, GO:0045892=IMP, GO:0008134=IPI, GO:0030618=IDA, GO:0007369=TAS, GO:0008285=IEA, GO:0030324=IEA, GO:0010718=ISS, GO:0005634=IDA, GO:0009952=ISS, GO:0046872=IEA, GO:0005829=TAS, GO:0035556=ISS, GO:0030513=IMP, GO:0005737=IDA, GO:0035265=IEA, GO:0045944=TAS, GO:0031053=TAS, GO:0060021=ISS, GO:0033613=IPI, GO:0030512=TAS, GO:0005667=IDA, GO:0070410=IPI, GO:0070411=IPI, GO:0051098=ISS, GO:0070412=IPI, GO:0007352=IMP, GO:0003677=IDA, GO:0006351=TAS, GO:0032444=IDA, GO:0009749=IEA, GO:0034713=IPI, GO:0031016=IEA, GO:0007492=IEA, GO:0003682=IEA, GO:0048617=IEA, GO:0070723=IDA} SMAD protein complex assembly, activin receptor signaling pathway, anterior/posterior pattern specification, cell fate commitment, common-partner SMAD protein phosphorylation, developmental growth, embryonic cranial skeleton morphogenesis, embryonic foregut morphogenesis, endoderm development, gastrulation, gene expression, in utero embryonic development, insulin secretion, intracellular signal transduction, lung development, mesoderm formation, negative regulation of cell proliferation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, negative regulation of transforming growth factor beta receptor signaling pathway, nodal signaling pathway, organ growth, palate development, pancreas development, paraxial mesoderm morphogenesis, pericardium development, positive regulation of BMP signaling pathway, positive regulation of epithelial to mesenchymal transition, positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, post-embryonic development, primary miRNA processing, regulation of binding, regulation of transforming growth factor beta receptor signaling pathway, response to cholesterol, response to glucose stimulus, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, ureteric bud development, zygotic specification of dorsal/ventral axis SMAD protein complex, activin responsive factor complex, cytoplasm, cytosol, nucleoplasm, nucleus, transcription factor complex DNA binding, I-SMAD binding, R-SMAD binding, SMAD binding, activating transcription factor binding, chromatin binding, co-SMAD binding, double-stranded DNA binding, metal ion binding, phosphatase binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transforming growth factor beta receptor binding, transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity, type I transforming growth factor beta receptor binding, ubiquitin protein ligase binding Human SMAD3 BHF-UCL UniProtKB {GO:0005515=PMID:21307346, GO:0030308=PMID:8774881, GO:0003700=PMID:9732876, GO:0044212=PMID:9732876, GO:0090263=PMID:20097766, GO:0005518=GO_REF:0000019, GO:0046332=GO_REF:0000019, GO:0030878=GO_REF:0000019, GO:0048701=GO_REF:0000019, GO:0042993=PMID:15799969, GO:0005622=GO_REF:0000002, GO:0048589=GO_REF:0000019, GO:0002520=GO_REF:0000019, GO:0031625=PMID:11278251, GO:0001102=PMID:17251190, GO:0030501=GO_REF:0000019, GO:0001707=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0060039=GO_REF:0000019, GO:0031490=GO_REF:0000019, GO:0001889=GO_REF:0000019, GO:0042110=GO_REF:0000019, GO:0002076=GO_REF:0000019, GO:0010694=GO_REF:0000019, GO:0051496=GO_REF:0000019, GO:0042060=PMID:19018011, GO:0008270=PMID:12686552, GO:0008134=PMID:9732876, GO:0030618=PMID:9111321, GO:0032731=GO_REF:0000019, GO:0010718=PMID:21307346, GO:0005637=PMID:15647271, GO:0001836=GO_REF:0000019, GO:0005634=PMID:9311995, GO:0035413=PMID:20097766, GO:0050927=GO_REF:0000019, GO:0005829=Reactome:REACT_150345, GO:0006955=PMID:16886151, GO:0031053=PMID:19018011, GO:0042177=PMID:20097766, GO:0051098=GO_REF:0000019, GO:0045668=GO_REF:0000019, GO:0007492=GO_REF:0000019, GO:0050728=GO_REF:0000019, GO:0000987=PMID:21947082, GO:0001657=GO_REF:0000019, GO:0043130=PMID:18794808, GO:0000988=PMID:18832382, GO:0010467=Reactome:REACT_71, GO:0033689=GO_REF:0000019, GO:0006367=Reactome:REACT_12627, GO:0070306=GO_REF:0000019, GO:0008013=PMID:20097766, GO:0001756=GO_REF:0000019, GO:0032916=GO_REF:0000019, GO:0060290=GO_REF:0000019, GO:0042803=PMID:8774881, GO:0009880=GO_REF:0000019, GO:0001947=GO_REF:0000019, GO:0003690=GO_REF:0000019, GO:1901313=PMID:21307346, GO:0061045=GO_REF:0000019, GO:0006810=PMID:15799969, GO:0016202=GO_REF:0000019, GO:0007179=PMID:9732876, GO:0017015=PMID:8774881, GO:0050678=GO_REF:0000019, GO:0030335=GO_REF:0000019, GO:0019901=PMID:12874272, GO:0019902=PMID:16751101, GO:0071141=PMID:21947082, GO:0000122=PMID:14555988, GO:0032924=PMID:15150278, GO:0005160=PMID:9311995, GO:0045216=PMID:18505915, GO:0043235=PMID:8774881, GO:0007183=PMID:9111321, GO:0045930=PMID:14555988, GO:0050776=GO_REF:0000019, GO:0038092=PMID:15150278, GO:0048340=GO_REF:0000019, GO:0005654=Reactome:REACT_121396, GO:0045893=PMID:9732876, GO:0005886=GO_REF:0000019, GO:0051894=GO_REF:0000019, GO:0005737=PMID:9311995, GO:0045944=PMID:14555988, GO:0032332=GO_REF:0000019, GO:0007050=PMID:14555988, GO:0030512=Reactome:REACT_120727, GO:0005667=PMID:21947082, GO:0001666=PMID:12411310, GO:0043066=GO_REF:0000019, GO:0006355=GO_REF:0000002, GO:0006919=PMID:15107418, GO:0050821=PMID:20097766, GO:0070410=PMID:9732876, GO:0070412=PMID:9311995, GO:0006917=PMID:15334054, GO:0006351=Reactome:REACT_121061, GO:0043565=PMID:10823886, GO:0032909=PMID:12411310, GO:0019049=PMID:15334054, GO:0048617=GO_REF:0000019, GO:0001933=PMID:20097766} P84022 Mothers against decapentaplegic homolog 3 protein 20120517 {GO:0005515=IPI, GO:0030308=IDA, GO:0003700=IDA, GO:0044212=IDA, GO:0090263=IMP, GO:0005518=IEA, GO:0046332=IEA, GO:0030878=IEA, GO:0048701=IEA, GO:0042993=IDA, GO:0005622=IEA, GO:0048589=IEA, GO:0002520=IEA, GO:0031625=IPI, GO:0001102=IPI, GO:0030501=IEA, GO:0001707=IEA, GO:0001701=IEA, GO:0060039=IEA, GO:0031490=IEA, GO:0001889=IEA, GO:0042110=IEA, GO:0002076=IEA, GO:0010694=IEA, GO:0051496=IEA, GO:0042060=TAS, GO:0008270=IDA, GO:0008134=IPI, GO:0030618=IDA, GO:0032731=IEA, GO:0010718=IDA, GO:0005637=IDA, GO:0001836=IEA, GO:0005634=IDA, GO:0035413=IMP, GO:0050927=IEA, GO:0005829=TAS, GO:0006955=IMP, GO:0031053=TAS, GO:0042177=IMP, GO:0051098=IEA, GO:0045668=IEA, GO:0007492=IEA, GO:0050728=IEA, GO:0000987=IDA, GO:0001657=IEA, GO:0043130=IDA, GO:0000988=IDA, GO:0010467=TAS, GO:0033689=IEA, GO:0006367=TAS, GO:0070306=IEA, GO:0008013=IPI, GO:0001756=IEA, GO:0032916=IEA, GO:0060290=IEA, GO:0042803=IPI, GO:0009880=IEA, GO:0001947=IEA, GO:0003690=IEA, GO:1901313=IMP, GO:0061045=IEA, GO:0006810=IDA, GO:0016202=IEA, GO:0007179=IDA, GO:0017015=IMP, GO:0050678=IEA, GO:0030335=IEA, GO:0019901=IPI, GO:0019902=IPI, GO:0071141=IDA, GO:0000122=IMP, GO:0032924=IMP, GO:0005160=IPI, GO:0045216=IMP, GO:0043235=IMP, GO:0007183=IDA, GO:0045930=IMP, GO:0050776=IEA, GO:0038092=IMP, GO:0048340=IEA, GO:0005654=TAS, GO:0045893=IDA, GO:0005886=IEA, GO:0051894=IEA, GO:0005737=IDA, GO:0045944=IMP, GO:0032332=IEA, GO:0007050=IMP, GO:0030512=TAS, GO:0005667=IDA, GO:0001666=IMP, GO:0043066=IEA, GO:0006355=IEA, GO:0006919=IMP, GO:0050821=IMP, GO:0070410=IPI, GO:0070412=IPI, GO:0006917=IMP, GO:0006351=TAS, GO:0043565=IDA, GO:0032909=IMP, GO:0019049=IDA, GO:0048617=IEA, GO:0001933=IMP} SMAD protein complex assembly, T cell activation, activation of cysteine-type endopeptidase activity involved in apoptotic process, activin receptor signaling pathway, cell cycle arrest, cell-cell junction organization, developmental growth, embryonic cranial skeleton morphogenesis, embryonic foregut morphogenesis, embryonic pattern specification, endoderm development, evasion or tolerance of host defenses by virus, gene expression, heart looping, immune response, immune system development, in utero embryonic development, induction of apoptosis, lens fiber cell differentiation, liver development, mesoderm formation, negative regulation of apoptotic process, negative regulation of cell growth, negative regulation of inflammatory response, negative regulation of mitotic cell cycle, negative regulation of osteoblast differentiation, negative regulation of osteoblast proliferation, negative regulation of protein catabolic process, negative regulation of protein phosphorylation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transforming growth factor beta receptor signaling pathway, negative regulation of wound healing, nodal signaling pathway, osteoblast development, paraxial mesoderm morphogenesis, pericardium development, positive regulation of alkaline phosphatase activity, positive regulation of bone mineralization, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of catenin import into nucleus, positive regulation of cell migration, positive regulation of chondrocyte differentiation, positive regulation of epithelial to mesenchymal transition, positive regulation of focal adhesion assembly, positive regulation of gene expression involved in extracellular matrix organization, positive regulation of interleukin-1 beta production, positive regulation of positive chemotaxis, positive regulation of stress fiber assembly, positive regulation of transcription factor import into nucleus, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of transforming growth factor beta3 production, primary miRNA processing, protein stabilization, regulation of binding, regulation of epithelial cell proliferation, regulation of immune response, regulation of striated muscle tissue development, regulation of transcription, DNA-dependent, regulation of transforming growth factor beta receptor signaling pathway, regulation of transforming growth factor beta2 production, release of cytochrome c from mitochondria, response to hypoxia, somitogenesis, thyroid gland development, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transdifferentiation, transforming growth factor beta receptor signaling pathway, transport, ureteric bud development, wound healing SMAD protein complex, cytoplasm, cytosol, intracellular, nuclear inner membrane, nucleoplasm, nucleus, plasma membrane, receptor complex, transcription factor complex R-SMAD binding, RNA polymerase II activating transcription factor binding, SMAD binding, beta-catenin binding, chromatin DNA binding, co-SMAD binding, collagen binding, core promoter proximal region sequence-specific DNA binding, double-stranded DNA binding, phosphatase binding, protein binding, protein binding transcription factor activity, protein homodimerization activity, protein kinase binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding, transforming growth factor beta receptor binding, transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity, ubiquitin binding, ubiquitin protein ligase binding, zinc ion binding Human SMAD4 BHF-UCL UniProtKB {GO:0005515=PMID:19135894, GO:0000987=PMID:18832382, GO:0000988=PMID:18832382, GO:0010467=Reactome:REACT_71, GO:0001658=GO_REF:0000019, GO:0030308=PMID:8774881, GO:0003700=PMID:17438144, GO:0006367=Reactome:REACT_12627, GO:0044212=PMID:17438144, GO:0005518=GO_REF:0000019, GO:0042803=PMID:8774881, GO:0042802=PMID:9111321, GO:0005622=GO_REF:0000002, GO:0048589=GO_REF:0000019, GO:0014033=GO_REF:0000019, GO:0060548=GO_REF:0000019, GO:0007179=PMID:9732876, GO:0017015=PMID:8774881, GO:0072134=GO_REF:0000019, GO:0072133=GO_REF:0000019, GO:0005813=GO_REF:0000052, GO:0071141=PMID:18832382, GO:0000122=Reactome:REACT_121111, GO:0030509=PMID:9389648, GO:0060391=GO_REF:0000024, GO:0001701=GO_REF:0000019, GO:0001702=GO_REF:0000019, GO:0007183=PMID:10823886, GO:0048733=GO_REF:0000019, GO:0005654=Reactome:REACT_121396, GO:0045893=PMID:9732876, GO:0051797=GO_REF:0000019, GO:0045892=PMID:8774881, GO:0030616=PMID:9389648, GO:0008285=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:0010718=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0060395=PMID:9707553, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_121368, GO:0005737=GO_REF:0000052, GO:0032525=GO_REF:0000019, GO:0045944=Reactome:REACT_120734, GO:0060021=GO_REF:0000024, GO:0071559=PMID:9707553, GO:0030511=PMID:19328798, GO:0001666=PMID:12411310, GO:0005667=PMID:17438144, GO:0006355=GO_REF:0000002, GO:0042177=PMID:20097766, GO:0005730=GO_REF:0000052, GO:0010862=GO_REF:0000024, GO:0048859=GO_REF:0000019, GO:0070411=PMID:9256479, GO:0051098=GO_REF:0000019, GO:0070412=PMID:9732876, GO:0048663=GO_REF:0000019, GO:0003677=PMID:9389648, GO:0006351=Reactome:REACT_121061, GO:0032444=PMID:9389648, GO:0043565=PMID:10823886, GO:0032909=PMID:12411310, GO:0007492=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0007498=GO_REF:0000019} Q13485 Mothers against decapentaplegic homolog 4 protein 20120708 {GO:0005515=IPI, GO:0000987=IDA, GO:0000988=IDA, GO:0010467=TAS, GO:0001658=IEA, GO:0030308=IDA, GO:0003700=IDA, GO:0006367=TAS, GO:0044212=IDA, GO:0005518=IEA, GO:0042803=IPI, GO:0042802=IPI, GO:0005622=IEA, GO:0048589=IEA, GO:0014033=IEA, GO:0060548=IEA, GO:0007179=IDA, GO:0017015=IMP, GO:0072134=IEA, GO:0072133=IEA, GO:0005813=IDA, GO:0071141=IDA, GO:0000122=TAS, GO:0030509=IDA, GO:0060391=ISS, GO:0001701=IEA, GO:0001702=IEA, GO:0007183=IDA, GO:0048733=IEA, GO:0005654=TAS, GO:0045893=IDA, GO:0051797=IEA, GO:0045892=IDA, GO:0030616=IDA, GO:0008285=IEA, GO:0008283=IEA, GO:0010718=ISS, GO:0005634=IDA, GO:0060395=IDA, GO:0046872=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0032525=IEA, GO:0045944=TAS, GO:0060021=ISS, GO:0071559=IDA, GO:0030511=IDA, GO:0001666=IMP, GO:0005667=IDA, GO:0006355=IEA, GO:0042177=IMP, GO:0005730=IDA, GO:0010862=ISS, GO:0048859=IEA, GO:0070411=IPI, GO:0051098=IEA, GO:0070412=IPI, GO:0048663=IEA, GO:0003677=IDA, GO:0006351=TAS, GO:0032444=IDA, GO:0043565=IDA, GO:0032909=IMP, GO:0007492=IEA, GO:0003682=IEA, GO:0007498=IEA} BMP signaling pathway, SMAD protein complex assembly, SMAD protein signal transduction, branching involved in ureteric bud morphogenesis, cell proliferation, developmental growth, endoderm development, formation of anatomical boundary, gastrulation with mouth forming second, gene expression, in utero embryonic development, mesoderm development, metanephric mesenchyme morphogenesis, negative regulation of cell death, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of protein catabolic process, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, nephrogenic mesenchyme morphogenesis, neural crest cell differentiation, neuron fate commitment, palate development, positive regulation of SMAD protein import into nucleus, positive regulation of epithelial to mesenchymal transition, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of transforming growth factor beta receptor signaling pathway, regulation of binding, regulation of hair follicle development, regulation of transcription, DNA-dependent, regulation of transforming growth factor beta receptor signaling pathway, regulation of transforming growth factor beta2 production, response to hypoxia, response to transforming growth factor beta stimulus, sebaceous gland development, somite rostral/caudal axis specification, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway SMAD protein complex, activin responsive factor complex, centrosome, cytoplasm, cytosol, intracellular, nucleolus, nucleoplasm, nucleus, transcription factor complex DNA binding, I-SMAD binding, R-SMAD binding, chromatin binding, collagen binding, core promoter proximal region sequence-specific DNA binding, identical protein binding, metal ion binding, protein binding, protein binding transcription factor activity, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding, transforming growth factor beta receptor, common-partner cytoplasmic mediator activity Human UniProtKB:Q9UPN9 SMAD5 BHF-UCL UniProtKB {GO:0071773=GO_REF:0000024, GO:0030618=PMID:19018011, GO:0005515=PMID:15647271, GO:0001657=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0051216=GO_REF:0000019, GO:0005634=PMID:19018011, GO:0007281=GO_REF:0000019, GO:0060048=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_12080, GO:0009880=GO_REF:0000024, GO:0005622=PMID:9759503, GO:0005737=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0001880=GO_REF:0000019, GO:0007179=PMID:10708948, GO:1901522=GO_REF:0000024, GO:0031625=PMID:11278251, GO:0005667=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0002051=GO_REF:0000019, GO:0030509=GO_REF:0000024, GO:0000979=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0045669=GO_REF:0000019, GO:0060348=GO_REF:0000019, GO:0007165=PMID:9759503, GO:0071407=GO_REF:0000019, GO:0030218=GO_REF:0000019, GO:0005654=Reactome:REACT_12067, GO:0006468=GO_REF:0000019, GO:0005057=PMID:8673135, GO:0016021=PMID:10708949, GO:0045893=PMID:10708949} Q99717 Mothers against decapentaplegic homolog 5 protein 20121203 {GO:0071773=ISS, GO:0030618=TAS, GO:0005515=IPI, GO:0001657=IEA, GO:0003700=IEA, GO:0051216=IEA, GO:0005634=TAS, GO:0007281=IEA, GO:0060048=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0009880=ISS, GO:0005622=NAS, GO:0005737=IEA, GO:0045944=IEA, GO:0001880=IEA, GO:0007179=NAS, GO:1901522=ISS, GO:0031625=IPI, GO:0005667=IEA, GO:0006355=IEA, GO:0002051=IEA, GO:0030509=ISS, GO:0000979=IEA, GO:0006351=IEA, GO:0045669=IEA, GO:0060348=IEA, GO:0007165=NAS, GO:0071407=IEA, GO:0030218=IEA, GO:0005654=TAS, GO:0006468=IEA, GO:0005057=NAS, GO:0016021=NAS, GO:0045893=NAS} BMP signaling pathway, Mullerian duct regression, bone development, cardiac muscle contraction, cartilage development, cellular response to BMP stimulus, cellular response to organic cyclic compound, embryonic pattern specification, erythrocyte differentiation, germ cell development, osteoblast fate commitment, positive regulation of osteoblast differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus, positive regulation of transcription, DNA-dependent, protein phosphorylation, regulation of transcription, DNA-dependent, signal transduction, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, ureteric bud development cytoplasm, cytosol, integral to membrane, intracellular, nucleoplasm, nucleus, transcription factor complex RNA polymerase II core promoter sequence-specific DNA binding, metal ion binding, protein binding, receptor signaling protein activity, sequence-specific DNA binding transcription factor activity, transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity, ubiquitin protein ligase binding Human UniProtKB:P97454 SMAD6 BHF-UCL UniProtKB {GO:0005515=PMID:16491121, GO:0001657=GO_REF:0000019, GO:0043627=GO_REF:0000019, GO:0010991=PMID:9436979, GO:0003700=GO_REF:0000002, GO:0030617=PMID:19047146, GO:0044212=PMID:16491121, GO:0005634=PMID:16491121, GO:0060394=PMID:19047146, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_115888, GO:0030514=PMID:9436979, GO:0070698=PMID:9436979, GO:0006955=PMID:16886151, GO:0005737=PMID:19018011, GO:0007179=GO_REF:0000002, GO:0043154=PMID:19047146, GO:0031625=PMID:11278251, GO:0030512=PMID:19047146, GO:0005667=GO_REF:0000002, GO:0043066=PMID:19047146, GO:0031589=PMID:16491121, GO:0070410=PMID:9256479, GO:0070411=PMID:9256479, GO:0070412=PMID:9256479, GO:0030509=Reactome:REACT_12034, GO:0007352=PMID:9436979, GO:0006351=GO_REF:0000037, GO:0034713=PMID:9436979, GO:0003682=PMID:16491121, GO:0034616=PMID:9256479, GO:0045750=PMID:19047146} O43541 Mothers against decapentaplegic homolog 6 protein 20100310 {GO:0005515=IPI, GO:0001657=IEA, GO:0043627=IEA, GO:0010991=IDA, GO:0003700=IEA, GO:0030617=IMP, GO:0044212=IDA, GO:0005634=IDA, GO:0060394=IMP, GO:0046872=IEA, GO:0005829=TAS, GO:0030514=IDA, GO:0070698=IDA, GO:0006955=IMP, GO:0005737=TAS, GO:0007179=IEA, GO:0043154=IMP, GO:0031625=IPI, GO:0030512=IMP, GO:0005667=IEA, GO:0043066=IMP, GO:0031589=IMP, GO:0070410=IPI, GO:0070411=IPI, GO:0070412=IPI, GO:0030509=TAS, GO:0007352=IMP, GO:0006351=IEA, GO:0034713=IDA, GO:0003682=IDA, GO:0034616=IEP, GO:0045750=IMP} BMP signaling pathway, cell-substrate adhesion, immune response, negative regulation of BMP signaling pathway, negative regulation of SMAD protein complex assembly, negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of pathway-restricted SMAD protein phosphorylation, negative regulation of transforming growth factor beta receptor signaling pathway, positive regulation of S phase of mitotic cell cycle, response to estrogen stimulus, response to laminar fluid shear stress, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, ureteric bud development, zygotic specification of dorsal/ventral axis cytoplasm, cytosol, nucleus, transcription factor complex I-SMAD binding, R-SMAD binding, chromatin binding, co-SMAD binding, metal ion binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding, transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity, type I activin receptor binding, type I transforming growth factor beta receptor binding, ubiquitin protein ligase binding Human UniProtKB:Q9HCE7 SMAD7 BHF-UCL UniProtKB {GO:0005515=PMID:16720724, GO:0010467=Reactome:REACT_71, GO:0001657=GO_REF:0000019, GO:0006367=Reactome:REACT_12627, GO:0003700=GO_REF:0000002, GO:0055010=GO_REF:0000024, GO:0044212=PMID:17438144, GO:0008013=PMID:18593713, GO:0005518=GO_REF:0000019, GO:0016342=PMID:18593713, GO:0048844=GO_REF:0000024, GO:0005622=GO_REF:0000002, GO:0060373=PMID:18952608, GO:0010944=PMID:17438144, GO:0031398=PMID:16720724, GO:0051444=PMID:18593713, GO:0007179=Reactome:REACT_120850, GO:0031397=PMID:18593713, GO:0017015=PMID:18952608, GO:0031625=PMID:16720724, GO:0030336=PMID:19018011, GO:0022409=PMID:18593713, GO:0030509=Reactome:REACT_12034, GO:0000122=PMID:17438144, GO:0032925=PMID:16720724, GO:0010801=PMID:18593713, GO:0055117=GO_REF:0000024, GO:0005654=Reactome:REACT_121185, GO:0060389=GO_REF:0000024, GO:0030617=PMID:9256479, GO:0005886=PMID:12151385, GO:0034333=PMID:18593713, GO:0032436=PMID:11278251, GO:0005634=PMID:12151385, GO:0010719=PMID:18762808, GO:0060394=PMID:17438144, GO:0046872=GO_REF:0000037, GO:0043433=PMID:17438144, GO:0005829=Reactome:REACT_160299, GO:0035556=GO_REF:0000019, GO:0030514=PMID:17438144, GO:0005737=PMID:17438144, GO:0005913=PMID:18593713, GO:0048185=PMID:16720724, GO:0033137=PMID:18593713, GO:0045944=Reactome:REACT_120734, GO:0034629=PMID:18593713, GO:0030512=PMID:12151385, GO:0005667=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0043066=PMID:19018011, GO:0060412=GO_REF:0000024, GO:0050821=PMID:18593713, GO:0070411=PMID:9256479, GO:0006351=Reactome:REACT_121061, GO:0034713=PMID:11278251, GO:0034616=PMID:9256479} O15105 Mothers against decapentaplegic homolog 7 protein 20090108 {GO:0005515=IPI, GO:0010467=TAS, GO:0001657=IEA, GO:0006367=TAS, GO:0003700=IEA, GO:0055010=ISS, GO:0044212=IDA, GO:0008013=IPI, GO:0005518=IEA, GO:0016342=IDA, GO:0048844=ISS, GO:0005622=IEA, GO:0060373=IC, GO:0010944=IDA, GO:0031398=IDA, GO:0051444=IDA, GO:0007179=TAS, GO:0031397=IDA, GO:0017015=IC, GO:0031625=IPI, GO:0030336=TAS, GO:0022409=IDA, GO:0030509=TAS, GO:0000122=IDA, GO:0032925=IDA, GO:0010801=IDA, GO:0055117=ISS, GO:0005654=TAS, GO:0060389=ISS, GO:0030617=IDA, GO:0005886=IDA, GO:0034333=IMP, GO:0032436=IDA, GO:0005634=IDA, GO:0010719=IC, GO:0060394=IDA, GO:0046872=IEA, GO:0043433=IDA, GO:0005829=TAS, GO:0035556=IEA, GO:0030514=IDA, GO:0005737=IDA, GO:0005913=IDA, GO:0048185=IPI, GO:0033137=IDA, GO:0045944=TAS, GO:0034629=IDA, GO:0030512=IDA, GO:0005667=IEA, GO:0006355=IEA, GO:0043066=TAS, GO:0060412=ISS, GO:0050821=IDA, GO:0070411=IPI, GO:0006351=TAS, GO:0034713=IPI, GO:0034616=IEP} BMP signaling pathway, adherens junction assembly, artery morphogenesis, cellular protein complex localization, gene expression, intracellular signal transduction, negative regulation of BMP signaling pathway, negative regulation of apoptotic process, negative regulation of cell migration, negative regulation of epithelial to mesenchymal transition, negative regulation of pathway-restricted SMAD protein phosphorylation, negative regulation of peptidyl-serine phosphorylation, negative regulation of peptidyl-threonine phosphorylation, negative regulation of protein ubiquitination, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription by competitive promoter binding, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transforming growth factor beta receptor signaling pathway, negative regulation of ubiquitin-protein ligase activity, pathway-restricted SMAD protein phosphorylation, positive regulation of cell-cell adhesion, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of protein ubiquitination, positive regulation of transcription from RNA polymerase II promoter, protein stabilization, regulation of activin receptor signaling pathway, regulation of cardiac muscle contraction, regulation of transcription, DNA-dependent, regulation of transforming growth factor beta receptor signaling pathway, regulation of ventricular cardiac muscle cell membrane depolarization, response to laminar fluid shear stress, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, ureteric bud development, ventricular cardiac muscle tissue morphogenesis, ventricular septum morphogenesis catenin complex, cell-cell adherens junction, cytoplasm, cytosol, intracellular, nucleoplasm, nucleus, plasma membrane, transcription factor complex I-SMAD binding, activin binding, beta-catenin binding, collagen binding, metal ion binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding, transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity, type I transforming growth factor beta receptor binding, ubiquitin protein ligase binding Human UniProtKB:P36896 SMAD9 BHF-UCL UniProtKB {GO:0030618=PMID:19018011, GO:0005667=GO_REF:0000002, GO:0001657=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0051216=GO_REF:0000019, GO:0045597=GO_REF:0000019, GO:0005634=PMID:19018011, GO:0030509=PMID:19018011, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_12080, GO:0005622=PMID:9256479, GO:0060348=GO_REF:0000019, GO:0071407=GO_REF:0000019, GO:0001880=GO_REF:0000019, GO:0005654=Reactome:REACT_12067, GO:0006468=GO_REF:0000019, GO:0030901=GO_REF:0000019, GO:0007179=GO_REF:0000002, GO:0045893=GO_REF:0000019, GO:0030902=GO_REF:0000019} O15198 Mothers against decapentaplegic homolog 9 protein 20090120 {GO:0030618=TAS, GO:0005667=IEA, GO:0001657=IEA, GO:0001666=IEA, GO:0003700=IEA, GO:0051216=IEA, GO:0045597=IEA, GO:0005634=TAS, GO:0030509=TAS, GO:0003677=IEA, GO:0006351=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0005622=TAS, GO:0060348=IEA, GO:0071407=IEA, GO:0001880=IEA, GO:0005654=TAS, GO:0006468=IEA, GO:0030901=IEA, GO:0007179=IEA, GO:0045893=IEA, GO:0030902=IEA} BMP signaling pathway, Mullerian duct regression, bone development, cartilage development, cellular response to organic cyclic compound, hindbrain development, midbrain development, positive regulation of cell differentiation, positive regulation of transcription, DNA-dependent, protein phosphorylation, response to hypoxia, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, ureteric bud development cytosol, intracellular, nucleoplasm, nucleus, transcription factor complex DNA binding, metal ion binding, sequence-specific DNA binding transcription factor activity, transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity Human SMAGP HPA UniProtKB {GO:0030054=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0016021=GO_REF:0000037, GO:0030659=GO_REF:0000039} Q0VAQ4 Small cell adhesion glycoprotein protein 20110516 {GO:0030054=IDA, GO:0005886=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0016021=IEA, GO:0030659=IEA} cell junction, cytoplasmic vesicle membrane, integral to membrane, nucleolus, nucleus, plasma membrane Human SMAP1 UniProtKB UniProtKB {GO:0008060=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0045648=GO_REF:0000019, GO:0030276=GO_REF:0000019, GO:0032312=GO_REF:0000002, GO:2000369=GO_REF:0000019, GO:0008270=GO_REF:0000002} Q8IYB5 Stromal membrane-associated protein 1 protein 20130413 {GO:0008060=IEA, GO:0005737=IEA, GO:0005886=IEA, GO:0045648=IEA, GO:0030276=IEA, GO:0032312=IEA, GO:2000369=IEA, GO:0008270=IEA} positive regulation of erythrocyte differentiation, regulation of ARF GTPase activity, regulation of clathrin-mediated endocytosis cytoplasm, plasma membrane ARF GTPase activator activity, clathrin binding, zinc ion binding Human UniProtKB-SubCell:SL-0039 SMAP2 HPA UniProtKB {GO:0008060=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0032312=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002} Q8WU79 Stromal membrane-associated protein 2 protein 20090616 {GO:0008060=IEA, GO:0005737=IDA, GO:0032312=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA} regulation of ARF GTPase activity cytoplasm, nucleolus, nucleus ARF GTPase activator activity, zinc ion binding Human SMARCA1 GOC UniProtKB {GO:0005515=PMID:14609955, GO:0070615=PMID:15640247, GO:0043044=PMID:15640247, GO:0004386=GO_REF:0000037, GO:0031491=GO_REF:0000002, GO:0005634=PMID:14609955, GO:0090537=PMID:15640247, GO:0003677=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0006351=PMID:14609955, GO:0000733=PMID:22705370, GO:0036310=PMID:22705370, GO:0007420=PMID:14609955, GO:0030182=GO_REF:0000024, GO:0006338=PMID:14609955, GO:0016589=PMID:20850016, GO:0045893=PMID:14609955, GO:0008094=PMID:14609955} P28370 Probable global transcription activator SNF2L1 protein 20130413 {GO:0005515=IPI, GO:0070615=IDA, GO:0043044=IDA, GO:0004386=IEA, GO:0031491=IEA, GO:0005634=IDA, GO:0090537=IDA, GO:0003677=IEA, GO:0005524=IEA, GO:0006351=IMP, GO:0000733=IDA, GO:0036310=IDA, GO:0007420=IMP, GO:0030182=ISS, GO:0006338=IDA, GO:0016589=IDA, GO:0045893=IMP, GO:0008094=IDA} ATP-dependent chromatin remodeling, DNA strand renaturation, brain development, chromatin remodeling, neuron differentiation, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent CERF complex, NURF complex, nucleus ATP binding, DNA binding, DNA-dependent ATPase activity, annealing helicase activity, helicase activity, nucleosome binding, nucleosome-dependent ATPase activity, protein binding Human SMARCA2 BHF-UCL UniProtKB {GO:0005515=PMID:12065415, GO:0030308=PMID:12065415, GO:0000790=PMID:12065415, GO:0071565=GO_REF:0000024, GO:0008285=GO_REF:0000019, GO:0044212=PMID:17984088, GO:0005634=GO_REF:0000052, GO:0071778=PMID:12837248, GO:0016818=GO_REF:0000002, GO:0035887=GO_REF:0000019, GO:0071564=GO_REF:0000024, GO:0043231=GO_REF:0000052, GO:0016514=PMID:11078522, GO:0045944=PMID:17938176, GO:0006338=PMID:17938176, GO:0045111=GO_REF:0000052, GO:0008094=PMID:17938176, GO:0006355=PMID:8670841, GO:0001105=PMID:17984088, GO:0006357=PMID:8223438, GO:0003713=PMID:8223438, GO:0004386=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0000122=PMID:17938176, GO:0005524=GO_REF:0000037, GO:0007399=GO_REF:0000037, GO:0005654=PMID:8670841, GO:0045893=PMID:8208605, GO:0045892=PMID:12065415} P51531 Probable global transcription activator SNF2L2 protein 20110504 {GO:0005515=IPI, GO:0030308=IMP, GO:0000790=IDA, GO:0071565=ISS, GO:0008285=IEA, GO:0044212=IDA, GO:0005634=IDA, GO:0071778=IDA, GO:0016818=IEA, GO:0035887=IEA, GO:0071564=ISS, GO:0043231=IDA, GO:0016514=IDA, GO:0045944=TAS, GO:0006338=TAS, GO:0045111=IDA, GO:0008094=TAS, GO:0006355=TAS, GO:0001105=IDA, GO:0006357=TAS, GO:0003713=TAS, GO:0004386=IEA, GO:0005730=IDA, GO:0000122=TAS, GO:0005524=IEA, GO:0007399=IEA, GO:0005654=TAS, GO:0045893=IMP, GO:0045892=IDA} aortic smooth muscle cell differentiation, chromatin remodeling, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, nervous system development, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent SWI/SNF complex, WINAC complex, intermediate filament cytoskeleton, intracellular membrane-bounded organelle, nBAF complex, npBAF complex, nuclear chromatin, nucleolus, nucleoplasm, nucleus ATP binding, DNA-dependent ATPase activity, RNA polymerase II transcription coactivator activity, helicase activity, hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, protein binding, transcription coactivator activity, transcription regulatory region DNA binding Human SMARCA4 ENSEMBL UniProtKB {GO:0005515=PMID:12065415, GO:0000792=GO_REF:0000019, GO:0071565=GO_REF:0000019, GO:0000790=PMID:12065415, GO:0030308=PMID:12065415, GO:0010424=GO_REF:0000019, GO:0071778=PMID:12837248, GO:0050681=PMID:18487222, GO:0035887=GO_REF:0000019, GO:0071564=GO_REF:0000019, GO:0030198=GO_REF:0000019, GO:0070577=PMID:17582821, GO:0008094=PMID:8232556, GO:0003407=PMID:18816825, GO:0000977=GO_REF:0000019, GO:0005719=GO_REF:0000019, GO:0003714=PMID:18487222, GO:0003713=PMID:16687403, GO:0060766=PMID:18487222, GO:0006337=PMID:8895581, GO:0000122=GO_REF:0000019, GO:0030957=PMID:16687403, GO:0043923=PMID:16687403, GO:0045749=PMID:19149898, GO:0060347=GO_REF:0000019, GO:0001889=GO_REF:0000019, GO:0043966=GO_REF:0000019, GO:0043388=GO_REF:0000019, GO:0045893=PMID:8208605, GO:0045892=PMID:12065415, GO:0008134=GO_REF:0000019, GO:0001835=GO_REF:0000019, GO:0001832=GO_REF:0000019, GO:0006346=GO_REF:0000019, GO:0005634=PMID:11726552, GO:0048730=GO_REF:0000019, GO:0002039=PMID:11950834, GO:0060318=GO_REF:0000019, GO:0051091=PMID:17938176, GO:0016514=PMID:8804307, GO:0045944=GO_REF:0000019, GO:0006338=GO_REF:0000019, GO:0006357=PMID:8804307, GO:0004386=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0003677=GO_REF:0000002, GO:0048562=GO_REF:0000019, GO:0007399=GO_REF:0000037, GO:0005726=GO_REF:0000019, GO:0000902=GO_REF:0000019, GO:0047485=PMID:12917342, GO:0030216=GO_REF:0000019, GO:0007403=GO_REF:0000019, GO:0019827=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0035116=GO_REF:0000019, GO:0030900=GO_REF:0000019, GO:0030902=GO_REF:0000019, GO:0001570=GO_REF:0000019} Q9HBD4 SMARCA4 isoform 2 protein 20130413 {GO:0005515=IPI, GO:0000792=IEA, GO:0071565=IEA, GO:0000790=IDA, GO:0030308=IMP, GO:0010424=IEA, GO:0071778=IDA, GO:0050681=IPI, GO:0035887=IEA, GO:0071564=IEA, GO:0030198=IEA, GO:0070577=IDA, GO:0008094=IGI, GO:0003407=IEP, GO:0000977=IEA, GO:0005719=IEA, GO:0003714=IDA, GO:0003713=IMP, GO:0060766=IMP, GO:0006337=IDA, GO:0000122=IEA, GO:0030957=IPI, GO:0043923=IMP, GO:0045749=TAS, GO:0060347=IEA, GO:0001889=IEA, GO:0043966=IEA, GO:0043388=IEA, GO:0045893=IMP, GO:0045892=IDA, GO:0008134=IEA, GO:0001835=IEA, GO:0001832=IEA, GO:0006346=IEA, GO:0005634=IDA, GO:0048730=IEA, GO:0002039=IPI, GO:0060318=IEA, GO:0051091=IDA, GO:0016514=IDA, GO:0045944=IEA, GO:0006338=IEA, GO:0006357=NAS, GO:0004386=IEA, GO:0003676=IEA, GO:0005524=IEA, GO:0003677=IEA, GO:0048562=IEA, GO:0007399=IEA, GO:0005726=IEA, GO:0000902=IEA, GO:0047485=IPI, GO:0030216=IEA, GO:0007403=IEA, GO:0019827=IEA, GO:0003682=IEA, GO:0035116=IEA, GO:0030900=IEA, GO:0030902=IEA, GO:0001570=IEA} DNA methylation on cytosine within a CG sequence, aortic smooth muscle cell differentiation, blastocyst growth, blastocyst hatching, cell morphogenesis, chromatin remodeling, definitive erythrocyte differentiation, embryonic hindlimb morphogenesis, embryonic organ morphogenesis, epidermis morphogenesis, extracellular matrix organization, forebrain development, glial cell fate determination, heart trabecula formation, hindbrain development, histone H3 acetylation, keratinocyte differentiation, liver development, methylation-dependent chromatin silencing, negative regulation of S phase of mitotic cell cycle, negative regulation of androgen receptor signaling pathway, negative regulation of cell growth, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, nervous system development, neural retina development, nucleosome disassembly, positive regulation by host of viral transcription, positive regulation of DNA binding, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, stem cell maintenance, vasculogenesis SWI/SNF complex, WINAC complex, heterochromatin, nBAF complex, npBAF complex, nuclear chromatin, nuclear euchromatin, nucleus, perichromatin fibrils ATP binding, DNA binding, DNA-dependent ATPase activity, RNA polymerase II regulatory region sequence-specific DNA binding, Tat protein binding, androgen receptor binding, chromatin binding, helicase activity, histone acetyl-lysine binding, nucleic acid binding, p53 binding, protein N-terminus binding, protein binding, transcription coactivator activity, transcription corepressor activity, transcription factor binding Human Ensembl:ENSMUSP00000096547 SMARCA5 GOC UniProtKB {GO:0005515=PMID:15543136, GO:0000793=PMID:12972596, GO:0006200=PMID:12972596, GO:0005634=GO_REF:0000052, GO:0009790=GO_REF:0000019, GO:0006302=GO_REF:0000019, GO:0042393=PMID:12972596, GO:0000183=GO_REF:0000019, GO:0016584=PMID:9836642, GO:0006338=PMID:9836642, GO:0016589=PMID:20850016, GO:0016887=PMID:12972596, GO:0043596=PMID:15543136, GO:0006352=PMID:9836642, GO:0006357=PMID:9730600, GO:0043044=PMID:15543136, GO:0006334=Reactome:REACT_22344, GO:0004386=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0031491=GO_REF:0000002, GO:0031213=PMID:9836642, GO:0003677=PMID:12972596, GO:0005524=PMID:12972596, GO:0034080=Reactome:REACT_22186, GO:0005654=Reactome:REACT_22217, GO:0005677=GO_REF:0000019} O60264 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 protein 20130413 {GO:0005515=IPI, GO:0000793=IDA, GO:0006200=IDA, GO:0005634=IDA, GO:0009790=IEA, GO:0006302=IEA, GO:0042393=IDA, GO:0000183=IEA, GO:0016584=IDA, GO:0006338=IDA, GO:0016589=IDA, GO:0016887=IDA, GO:0043596=IDA, GO:0006352=IDA, GO:0006357=TAS, GO:0043044=IMP, GO:0006334=TAS, GO:0004386=IEA, GO:0005730=IDA, GO:0031491=IEA, GO:0031213=IPI, GO:0003677=IDA, GO:0005524=IDA, GO:0034080=TAS, GO:0005654=TAS, GO:0005677=IEA} ATP catabolic process, ATP-dependent chromatin remodeling, CENP-A containing nucleosome assembly at centromere, DNA-dependent transcription, initiation, chromatin remodeling, chromatin silencing at rDNA, double-strand break repair, embryo development, nucleosome assembly, nucleosome positioning, regulation of transcription from RNA polymerase II promoter NURF complex, RSF complex, chromatin silencing complex, condensed chromosome, nuclear replication fork, nucleolus, nucleoplasm, nucleus ATP binding, ATPase activity, DNA binding, helicase activity, histone binding, nucleosome binding, protein binding Human SMARCAD1 HPA UniProtKB {GO:0000792=GO_REF:0000024, GO:0005515=PMID:18675275, GO:0070932=PMID:21549307, GO:0070933=PMID:21549307, GO:0043044=PMID:22960744, GO:0005730=GO_REF:0000052, GO:0035861=PMID:22960744, GO:0004386=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0003676=PMID:11031099, GO:0003677=PMID:18675275, GO:0005524=GO_REF:0000037, GO:0016363=PMID:11031099, GO:0051304=PMID:21549307, GO:0051260=PMID:11031099, GO:0006338=PMID:21549307, GO:0000018=PMID:11031099, GO:0045893=PMID:11031099, GO:0043596=PMID:21549307, GO:0000729=PMID:22960744, GO:0009117=PMID:11031099, GO:0016568=PMID:11031099} Q9H4L7 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 protein 20090616 {GO:0000792=ISS, GO:0005515=IPI, GO:0070932=IMP, GO:0070933=IMP, GO:0043044=IMP, GO:0005730=IDA, GO:0035861=IDA, GO:0004386=IEA, GO:0005634=IDA, GO:0003676=NAS, GO:0003677=IDA, GO:0005524=IEA, GO:0016363=NAS, GO:0051304=IMP, GO:0051260=NAS, GO:0006338=NAS, GO:0000018=IEP, GO:0045893=NAS, GO:0043596=IDA, GO:0000729=IMP, GO:0009117=NAS, GO:0016568=NAS} ATP-dependent chromatin remodeling, DNA double-strand break processing, chromatin modification, chromatin remodeling, chromosome separation, histone H3 deacetylation, histone H4 deacetylation, nucleotide metabolic process, positive regulation of transcription, DNA-dependent, protein homooligomerization, regulation of DNA recombination heterochromatin, nuclear matrix, nuclear replication fork, nucleolus, nucleus, site of double-strand break ATP binding, DNA binding, helicase activity, nucleic acid binding, protein binding NOT Human SMARCAL1 GOC UniProtKB {GO:0000733=PMID:22705370, GO:0036310=PMID:22705370, GO:0006357=PMID:18974355, GO:0004386=GO_REF:0000037, GO:0005634=PMID:18974355, GO:0006259=PMID:18974355, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000002, GO:0016568=GO_REF:0000002, GO:0008094=PMID:18974355} Q9NZC9 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 protein 20130413 {GO:0000733=IDA, GO:0036310=IDA, GO:0006357=IMP, GO:0004386=IEA, GO:0005634=IDA, GO:0006259=IMP, GO:0005524=IEA, GO:0003677=IEA, GO:0016568=IEA, GO:0008094=IMP} DNA metabolic process, DNA strand renaturation, chromatin modification, regulation of transcription from RNA polymerase II promoter nucleus ATP binding, DNA binding, DNA-dependent ATPase activity, annealing helicase activity, helicase activity Human SMARCB1 HPA UniProtKB {GO:0005515=PMID:16687403, GO:0071565=GO_REF:0000024, GO:0008285=GO_REF:0000033, GO:0001835=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0015074=PMID:7801128, GO:0071564=GO_REF:0000024, GO:0030154=GO_REF:0000033, GO:0045090=PMID:14963118, GO:0002039=PMID:11950834, GO:0051091=PMID:11950834, GO:0016514=PMID:8804307, GO:0045944=PMID:11950834, GO:0006338=PMID:11726552, GO:0001741=GO_REF:0000019, GO:0044772=GO_REF:0000033, GO:0006357=PMID:8804307, GO:0043044=GO_REF:0000033, GO:0003713=PMID:16687403, GO:0005730=GO_REF:0000052, GO:0006337=PMID:8895581, GO:0000228=GO_REF:0000002, GO:0030957=PMID:16687403, GO:0043923=PMID:16687403, GO:0006351=GO_REF:0000037, GO:0007399=GO_REF:0000037, GO:0006281=GO_REF:0000033, GO:0019048=GO_REF:0000037, GO:0005654=PMID:7801128} Q12824 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 protein 20090616 {GO:0005515=IPI, GO:0071565=ISS, GO:0008285=IBA, GO:0001835=IEA, GO:0005634=IDA, GO:0015074=TAS, GO:0071564=ISS, GO:0030154=IBA, GO:0045090=IDA, GO:0002039=IPI, GO:0051091=IDA, GO:0016514=IDA, GO:0045944=IDA, GO:0006338=IDA, GO:0001741=IEA, GO:0044772=IBA, GO:0006357=NAS, GO:0043044=IBA, GO:0003713=IMP, GO:0005730=IDA, GO:0006337=IDA, GO:0000228=IEA, GO:0030957=IPI, GO:0043923=IMP, GO:0006351=IEA, GO:0007399=IEA, GO:0006281=IBA, GO:0019048=IEA, GO:0005654=TAS} ATP-dependent chromatin remodeling, DNA integration, DNA repair, blastocyst hatching, cell differentiation, chromatin remodeling, mitotic cell cycle phase transition, negative regulation of cell proliferation, nervous system development, nucleosome disassembly, positive regulation by host of viral transcription, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, retroviral genome replication, transcription, DNA-dependent, virus-host interaction SWI/SNF complex, XY body, nBAF complex, npBAF complex, nuclear chromosome, nucleolus, nucleoplasm, nucleus Tat protein binding, p53 binding, protein binding, transcription coactivator activity NOT Human SMARCC1 HPA UniProtKB {GO:0005515=PMID:12917342, GO:0001741=GO_REF:0000019, GO:0008286=GO_REF:0000019, GO:0071565=GO_REF:0000024, GO:0006357=PMID:8804307, GO:0003713=PMID:8804307, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0071778=PMID:12837248, GO:0006337=PMID:8895581, GO:0071564=GO_REF:0000024, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0007399=GO_REF:0000037, GO:0047485=PMID:12917342, GO:0016514=PMID:8804307, GO:0003682=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0009887=GO_REF:0000019, GO:0006338=PMID:11726552, GO:0045893=PMID:11018012} Q92922 SWI/SNF complex subunit SMARCC1 protein 20101115 {GO:0005515=IPI, GO:0001741=IEA, GO:0008286=IEA, GO:0071565=ISS, GO:0006357=NAS, GO:0003713=NAS, GO:0005730=IDA, GO:0005634=IDA, GO:0071778=IDA, GO:0006337=IDA, GO:0071564=ISS, GO:0003677=IEA, GO:0006351=IEA, GO:0007399=IEA, GO:0047485=IPI, GO:0016514=IDA, GO:0003682=IEA, GO:0045944=IEA, GO:0009887=IEA, GO:0006338=IDA, GO:0045893=IDA} chromatin remodeling, insulin receptor signaling pathway, nervous system development, nucleosome disassembly, organ morphogenesis, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent SWI/SNF complex, WINAC complex, XY body, nBAF complex, npBAF complex, nucleolus, nucleus DNA binding, chromatin binding, protein N-terminus binding, protein binding, transcription coactivator activity NOT Human SMARCC2 HPA UniProtKB {GO:0005515=PMID:12917342, GO:0071565=GO_REF:0000024, GO:0006357=PMID:8804307, GO:0003713=PMID:8804307, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006337=PMID:8895581, GO:0003677=GO_REF:0000002, GO:0071564=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0007399=GO_REF:0000037, GO:0016514=PMID:8804307, GO:0003682=GO_REF:0000002, GO:0017053=PMID:12192000, GO:0006338=PMID:11726552, GO:0045893=PMID:11018012, GO:0045892=PMID:12192000} Q8TAQ2 SWI/SNF complex subunit SMARCC2 protein 20120912 {GO:0005515=IPI, GO:0071565=ISS, GO:0006357=NAS, GO:0003713=NAS, GO:0005730=IDA, GO:0005634=IDA, GO:0006337=IDA, GO:0003677=IEA, GO:0071564=ISS, GO:0006351=IEA, GO:0007399=IEA, GO:0016514=IDA, GO:0003682=IEA, GO:0017053=IPI, GO:0006338=IDA, GO:0045893=IDA, GO:0045892=IDA} chromatin remodeling, negative regulation of transcription, DNA-dependent, nervous system development, nucleosome disassembly, positive regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent SWI/SNF complex, nBAF complex, npBAF complex, nucleolus, nucleus, transcriptional repressor complex DNA binding, chromatin binding, protein binding, transcription coactivator activity NOT Human SMARCD1 BHF-UCL UniProtKB {GO:0005515=PMID:12917342, GO:0032947=PMID:12917342, GO:0071565=GO_REF:0000024, GO:0006357=PMID:8804307, GO:0016514=PMID:8804307, GO:0003713=PMID:8804307, GO:0006338=PMID:11726552, GO:0006337=PMID:8895581, GO:0048096=PMID:12917342, GO:0071564=GO_REF:0000024, GO:0007399=GO_REF:0000037} Q96GM5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 protein 20110811 {GO:0005515=IPI, GO:0032947=IDA, GO:0071565=ISS, GO:0006357=NAS, GO:0016514=IDA, GO:0003713=NAS, GO:0006338=IDA, GO:0006337=IDA, GO:0048096=IMP, GO:0071564=ISS, GO:0007399=IEA} chromatin remodeling, chromatin-mediated maintenance of transcription, nervous system development, nucleosome disassembly, regulation of transcription from RNA polymerase II promoter SWI/SNF complex, nBAF complex, npBAF complex protein binding, protein complex scaffold, transcription coactivator activity Human SMARCD2 BHF-UCL UniProtKB {GO:0006357=PMID:8804307, GO:0016514=PMID:8804307, GO:0003713=PMID:8804307, GO:0006338=PMID:11726552, GO:0006337=PMID:8895581, GO:0006351=GO_REF:0000037} Q92925 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 protein 20110811 {GO:0006357=NAS, GO:0016514=IDA, GO:0003713=NAS, GO:0006338=IDA, GO:0006337=IDA, GO:0006351=IEA} chromatin remodeling, nucleosome disassembly, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent SWI/SNF complex transcription coactivator activity Human SMARCD3 BHF-UCL UniProtKB {GO:0000790=PMID:17363140, GO:0071565=GO_REF:0000024, GO:0003407=PMID:18816825, GO:0006357=PMID:8804307, GO:0003713=PMID:8804307, GO:0003139=GO_REF:0000019, GO:0043393=GO_REF:0000019, GO:0005102=PMID:14701856, GO:0002052=PMID:18816825, GO:0035257=PMID:14701856, GO:0005634=PMID:18816825, GO:0006337=PMID:8895581, GO:0044281=Reactome:REACT_111217, GO:0071564=PMID:18816825, GO:0003219=GO_REF:0000019, GO:0006351=PMID:14701856, GO:0042692=GO_REF:0000019, GO:0016514=PMID:8804307, GO:0006338=PMID:18816825, GO:0005654=Reactome:REACT_19175, GO:0045893=PMID:14701856, GO:0044255=Reactome:REACT_22279, GO:0008134=PMID:14701856} Q6STE5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 protein 20110811 {GO:0000790=IDA, GO:0071565=ISS, GO:0003407=IEP, GO:0006357=NAS, GO:0003713=NAS, GO:0003139=IEA, GO:0043393=IEA, GO:0005102=IPI, GO:0002052=IDA, GO:0035257=IPI, GO:0005634=IDA, GO:0006337=IDA, GO:0044281=TAS, GO:0071564=IDA, GO:0003219=IEA, GO:0006351=IDA, GO:0042692=IEA, GO:0016514=IDA, GO:0006338=IC, GO:0005654=TAS, GO:0045893=IDA, GO:0044255=TAS, GO:0008134=IPI} cardiac right ventricle formation, cellular lipid metabolic process, chromatin remodeling, muscle cell differentiation, neural retina development, nucleosome disassembly, positive regulation of neuroblast proliferation, positive regulation of transcription, DNA-dependent, regulation of protein binding, regulation of transcription from RNA polymerase II promoter, secondary heart field specification, small molecule metabolic process, transcription, DNA-dependent SWI/SNF complex, nBAF complex, npBAF complex, nuclear chromatin, nucleoplasm, nucleus nuclear hormone receptor binding, receptor binding, transcription coactivator activity, transcription factor binding Human SMARCE1 HPA UniProtKB {GO:0005515=PMID:17363140, GO:0016922=PMID:17363140, GO:0071565=GO_REF:0000024, GO:0008080=PMID:12192000, GO:0006357=PMID:8804307, GO:0003713=PMID:8804307, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006337=PMID:8895581, GO:0000228=PMID:9435219, GO:0071564=GO_REF:0000024, GO:0003677=GO_REF:0000037, GO:0007399=GO_REF:0000037, GO:0047485=PMID:12917342, GO:0016514=PMID:8804307, GO:0017053=PMID:12192000, GO:0003682=PMID:9435219, GO:0006338=PMID:11726552, GO:0045892=PMID:12192000} Q969G3 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 protein 20080205 {GO:0005515=IPI, GO:0016922=IPI, GO:0071565=ISS, GO:0008080=IDA, GO:0006357=NAS, GO:0003713=NAS, GO:0005730=IDA, GO:0005634=IDA, GO:0006337=IDA, GO:0000228=TAS, GO:0071564=ISS, GO:0003677=IEA, GO:0007399=IEA, GO:0047485=IPI, GO:0016514=IDA, GO:0017053=IPI, GO:0003682=TAS, GO:0006338=IDA, GO:0045892=IDA} chromatin remodeling, negative regulation of transcription, DNA-dependent, nervous system development, nucleosome disassembly, regulation of transcription from RNA polymerase II promoter SWI/SNF complex, nBAF complex, npBAF complex, nuclear chromosome, nucleolus, nucleus, transcriptional repressor complex DNA binding, N-acetyltransferase activity, chromatin binding, ligand-dependent nuclear receptor binding, protein N-terminus binding, protein binding, transcription coactivator activity NOT Human SMC1A BHF-UCL UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:16438930, GO:0010467=Reactome:REACT_71, GO:0000236=Reactome:REACT_682, GO:0051276=GO_REF:0000002, GO:0030261=GO_REF:0000002, GO:0008280=PMID:11076961, GO:0030893=PMID:21242291, GO:0032876=PMID:15917200, GO:0005634=GO_REF:0000052, GO:0005829=Reactome:REACT_150294, GO:0000084=Reactome:REACT_899, GO:0000910=Reactome:REACT_1932, GO:0005737=GO_REF:0000052, GO:0000087=Reactome:REACT_910, GO:0007052=PMID:12199140, GO:0009314=PMID:11877377, GO:0000794=PMID:7757074, GO:0046982=PMID:11590136, GO:0005694=Reactome:REACT_150454, GO:0005730=GO_REF:0000052, GO:0006310=GO_REF:0000002, GO:0003777=PMID:12199140, GO:0005524=GO_REF:0000037, GO:0042770=PMID:11877377, GO:0000070=PMID:7757074, GO:0006281=PMID:11877377, GO:0007126=GO_REF:0000024, GO:0000398=Reactome:REACT_467, GO:0036033=GO_REF:0000019, GO:0019827=GO_REF:0000019, GO:0003682=PMID:11076961, GO:0000777=GO_REF:0000039, GO:0007062=PMID:15917200, GO:0000075=PMID:11877377, GO:0000776=PMID:11682612, GO:0005654=Reactome:REACT_150456, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0000775=Reactome:REACT_150445, GO:0007064=PMID:12199140} Q14683 Structural maintenance of chromosomes protein 1A protein 20100127 {GO:0008380=TAS, GO:0005515=IPI, GO:0010467=TAS, GO:0000236=TAS, GO:0051276=IEA, GO:0030261=IEA, GO:0008280=TAS, GO:0030893=IDA, GO:0032876=IMP, GO:0005634=IDA, GO:0005829=TAS, GO:0000084=TAS, GO:0000910=TAS, GO:0005737=IDA, GO:0000087=TAS, GO:0007052=TAS, GO:0009314=IEP, GO:0000794=TAS, GO:0046982=IPI, GO:0005694=TAS, GO:0005730=IDA, GO:0006310=IEA, GO:0003777=NAS, GO:0005524=IEA, GO:0042770=IDA, GO:0000070=TAS, GO:0006281=TAS, GO:0007126=ISS, GO:0000398=TAS, GO:0036033=IEA, GO:0019827=IEA, GO:0003682=IDA, GO:0000777=IEA, GO:0007062=IMP, GO:0000075=IDA, GO:0000776=IDA, GO:0005654=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0000775=TAS, GO:0007064=TAS} DNA recombination, DNA repair, M phase of mitotic cell cycle, RNA splicing, S phase of mitotic cell cycle, cell cycle checkpoint, chromosome condensation, chromosome organization, cytokinesis, gene expression, mRNA splicing, via spliceosome, meiosis, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, mitotic sister chromatid cohesion, mitotic sister chromatid segregation, mitotic spindle organization, negative regulation of DNA endoreduplication, response to radiation, signal transduction in response to DNA damage, sister chromatid cohesion, stem cell maintenance chromosome, chromosome, centromeric region, cohesin core heterodimer, condensed chromosome kinetochore, condensed nuclear chromosome, cytoplasm, cytosol, kinetochore, meiotic cohesin complex, nucleolus, nucleoplasm, nucleus ATP binding, chromatin binding, mediator complex binding, microtubule motor activity, protein binding, protein heterodimerization activity Human SMC1B UniProtKB UniProtKB {GO:0007126=GO_REF:0000019, GO:0006281=GO_REF:0000002, GO:0030261=GO_REF:0000002, GO:0030893=PMID:21242291, GO:0007062=GO_REF:0000019, GO:0034991=GO_REF:0000019, GO:0006310=GO_REF:0000002, GO:0000800=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0000775=GO_REF:0000039} Q8NDV3 Structural maintenance of chromosomes protein 1B protein 20110222 {GO:0007126=IEA, GO:0006281=IEA, GO:0030261=IEA, GO:0030893=IDA, GO:0007062=IEA, GO:0034991=IEA, GO:0006310=IEA, GO:0000800=IEA, GO:0003677=IEA, GO:0005524=IEA, GO:0000775=IEA} DNA recombination, DNA repair, chromosome condensation, meiosis, sister chromatid cohesion chromosome, centromeric region, lateral element, meiotic cohesin complex, nuclear meiotic cohesin complex ATP binding, DNA binding Human SMC2 ENSEMBL UniProtKB {GO:0005515=PMID:12589063, GO:0000796=GO_REF:0000002, GO:0000236=Reactome:REACT_682, GO:0000793=PMID:12589063, GO:0007076=GO_REF:0000002, GO:0010032=GO_REF:0000019, GO:0046982=PMID:9789013, GO:0005634=PMID:12589063, GO:0006310=GO_REF:0000002, GO:0051383=GO_REF:0000019, GO:0000228=PMID:10958694, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_150403, GO:0005737=PMID:12589063, GO:0006281=GO_REF:0000002, GO:0045132=GO_REF:0000019, GO:0000087=Reactome:REACT_910, GO:0007062=GO_REF:0000002, GO:0000278=Reactome:REACT_152, GO:0051301=GO_REF:0000037} Q5T821 Structural maintenance of chromosomes protein 2 protein 20130413 {GO:0005515=IPI, GO:0000796=IEA, GO:0000236=TAS, GO:0000793=IDA, GO:0007076=IEA, GO:0010032=IEA, GO:0046982=IPI, GO:0005634=IDA, GO:0006310=IEA, GO:0051383=IEA, GO:0000228=IDA, GO:0005524=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0006281=IEA, GO:0045132=IEA, GO:0000087=TAS, GO:0007062=IEA, GO:0000278=TAS, GO:0051301=IEA} DNA recombination, DNA repair, M phase of mitotic cell cycle, cell division, kinetochore organization, meiotic chromosome condensation, meiotic chromosome segregation, mitotic cell cycle, mitotic chromosome condensation, mitotic prometaphase, sister chromatid cohesion condensed chromosome, condensin complex, cytoplasm, cytosol, nuclear chromosome, nucleus ATP binding, protein binding, protein heterodimerization activity Human Ensembl:ENSMUSP00000099979 SMC3 BHF-UCL UniProtKB {GO:0005515=PMID:11983169, GO:0000236=Reactome:REACT_682, GO:0030893=PMID:21242291, GO:0032876=PMID:15917200, GO:0005634=PMID:9506951, GO:0016363=PMID:11590136, GO:0005829=Reactome:REACT_150294, GO:0000084=Reactome:REACT_899, GO:0000910=Reactome:REACT_1932, GO:0005737=PMID:11590136, GO:0000087=Reactome:REACT_910, GO:0007052=PMID:11590136, GO:0000785=PMID:19907496, GO:0006275=PMID:19907496, GO:0046982=PMID:11590136, GO:0005694=Reactome:REACT_150454, GO:0000800=GO_REF:0000019, GO:0003777=PMID:11590136, GO:0005524=GO_REF:0000037, GO:0005604=PMID:9015313, GO:0007165=PMID:12651860, GO:0008278=PMID:9506951, GO:0000922=PMID:11590136, GO:0007067=PMID:9506951, GO:0006281=GO_REF:0000037, GO:0045502=PMID:11590136, GO:0007126=PMID:12498344, GO:0036033=GO_REF:0000019, GO:0019827=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0007062=PMID:15917200, GO:0005654=Reactome:REACT_150456, GO:0034991=GO_REF:0000019, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0000775=Reactome:REACT_150445} Q9UQE7 Structural maintenance of chromosomes protein 3 protein 20100127 {GO:0005515=IPI, GO:0000236=TAS, GO:0030893=IDA, GO:0032876=IMP, GO:0005634=TAS, GO:0016363=IDA, GO:0005829=TAS, GO:0000084=TAS, GO:0000910=TAS, GO:0005737=IDA, GO:0000087=TAS, GO:0007052=IEP, GO:0000785=IDA, GO:0006275=IMP, GO:0046982=IPI, GO:0005694=TAS, GO:0000800=IEA, GO:0003777=NAS, GO:0005524=IEA, GO:0005604=TAS, GO:0007165=IDA, GO:0008278=NAS, GO:0000922=IDA, GO:0007067=TAS, GO:0006281=IEA, GO:0045502=IDA, GO:0007126=IDA, GO:0036033=IEA, GO:0019827=IEA, GO:0003682=IEA, GO:0007062=IMP, GO:0005654=TAS, GO:0034991=IEA, GO:0000278=TAS, GO:0000090=TAS, GO:0000775=TAS} DNA repair, M phase of mitotic cell cycle, S phase of mitotic cell cycle, cytokinesis, meiosis, mitosis, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, mitotic spindle organization, negative regulation of DNA endoreduplication, regulation of DNA replication, signal transduction, sister chromatid cohesion, stem cell maintenance basement membrane, chromatin, chromosome, chromosome, centromeric region, cohesin complex, cytoplasm, cytosol, lateral element, meiotic cohesin complex, nuclear matrix, nuclear meiotic cohesin complex, nucleoplasm, nucleus, spindle pole ATP binding, chromatin binding, dynein binding, mediator complex binding, microtubule motor activity, protein binding, protein heterodimerization activity Human SMC4 HPA UniProtKB {GO:0000796=PMID:11136719, GO:0000236=Reactome:REACT_682, GO:0007076=PMID:11136719, GO:0010032=GO_REF:0000019, GO:0046982=PMID:9789013, GO:0005694=GO_REF:0000002, GO:0030261=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0006310=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0051383=GO_REF:0000019, GO:0005524=PMID:11136719, GO:0005829=Reactome:REACT_150403, GO:0000070=PMID:11321372, GO:0005737=GO_REF:0000052, GO:0006281=GO_REF:0000002, GO:0045132=GO_REF:0000019, GO:0000087=Reactome:REACT_910, GO:0007062=GO_REF:0000002, GO:0000278=Reactome:REACT_152, GO:0051301=GO_REF:0000037} Q9NTJ3 Structural maintenance of chromosomes protein 4 protein 20090616 {GO:0000796=IDA, GO:0000236=TAS, GO:0007076=IDA, GO:0010032=IEA, GO:0046982=IPI, GO:0005694=IEA, GO:0030261=IEA, GO:0005730=IDA, GO:0006310=IEA, GO:0005634=IDA, GO:0051383=IEA, GO:0005524=TAS, GO:0005829=TAS, GO:0000070=TAS, GO:0005737=IDA, GO:0006281=IEA, GO:0045132=IEA, GO:0000087=TAS, GO:0007062=IEA, GO:0000278=TAS, GO:0051301=IEA} DNA recombination, DNA repair, M phase of mitotic cell cycle, cell division, chromosome condensation, kinetochore organization, meiotic chromosome condensation, meiotic chromosome segregation, mitotic cell cycle, mitotic chromosome condensation, mitotic prometaphase, mitotic sister chromatid segregation, sister chromatid cohesion chromosome, condensin complex, cytoplasm, cytosol, nucleolus, nucleus ATP binding, protein heterodimerization activity Human SMC5 UniProtKB UniProtKB {GO:0000781=PMID:17589526, GO:0030915=PMID:18086888, GO:0045842=PMID:19502785, GO:0005634=GO_REF:0000024, GO:0006303=PMID:16810316, GO:0005524=GO_REF:0000037, GO:0007067=GO_REF:0000037, GO:0000724=PMID:16810316, GO:0016605=PMID:17589526, GO:0000722=PMID:17589526, GO:0034184=PMID:19502785, GO:0051301=GO_REF:0000037, GO:0090398=PMID:17589526} Q8IY18 Structural maintenance of chromosomes protein 5 protein 20120214 {GO:0000781=IDA, GO:0030915=IDA, GO:0045842=IMP, GO:0005634=ISS, GO:0006303=IMP, GO:0005524=IEA, GO:0007067=IEA, GO:0000724=IMP, GO:0016605=IDA, GO:0000722=IMP, GO:0034184=IMP, GO:0051301=IEA, GO:0090398=IMP} cell division, cellular senescence, double-strand break repair via homologous recombination, double-strand break repair via nonhomologous end joining, mitosis, positive regulation of maintenance of mitotic sister chromatid cohesion, positive regulation of mitotic metaphase/anaphase transition, telomere maintenance via recombination PML body, Smc5-Smc6 complex, chromosome, telomeric region, nucleus ATP binding Human SMC6 LIFEdb UniProtKB {GO:0005622=GO_REF:0000054, GO:0000781=PMID:17589526, GO:0000724=GO_REF:0000002, GO:0016605=PMID:17589526, GO:0030915=PMID:18086888, GO:0000722=PMID:17589526, GO:0005524=GO_REF:0000037, GO:0090398=PMID:17589526} Q96SB8 Structural maintenance of chromosomes protein 6 protein 20100607 {GO:0005622=IDA, GO:0000781=IDA, GO:0000724=IEA, GO:0016605=IDA, GO:0030915=IDA, GO:0000722=IMP, GO:0005524=IEA, GO:0090398=IMP} cellular senescence, double-strand break repair via homologous recombination, telomere maintenance via recombination PML body, Smc5-Smc6 complex, chromosome, telomeric region, intracellular ATP binding Human SMCHD1 InterPro UniProtKB {GO:0001740=GO_REF:0000019, GO:0051276=GO_REF:0000002, GO:0005694=GO_REF:0000002, GO:0060821=GO_REF:0000019, GO:0005524=GO_REF:0000002} J3KTL8 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 protein 20130413 {GO:0001740=IEA, GO:0051276=IEA, GO:0005694=IEA, GO:0060821=IEA, GO:0005524=IEA} chromosome organization, inactivation of X chromosome by DNA methylation Barr body, chromosome ATP binding Human InterPro:IPR010935 SMCP HPA UniProtKB {GO:0005739=GO_REF:0000024, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0031966=GO_REF:0000039, GO:0007341=GO_REF:0000024, GO:0030317=GO_REF:0000024, GO:0007339=GO_REF:0000019} P49901 Sperm mitochondrial-associated cysteine-rich protein protein 20101115 {GO:0005739=ISS, GO:0003674=ND, GO:0005737=IDA, GO:0031966=IEA, GO:0007341=ISS, GO:0030317=ISS, GO:0007339=IEA} binding of sperm to zona pellucida, penetration of zona pellucida, sperm motility cytoplasm, mitochondrial membrane, mitochondrion molecular_function Human SMCR7 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0005741=PMID:21508961, GO:0007005=PMID:21508961, GO:0016021=GO_REF:0000037} Q96C03 Mitochondrial dynamic protein MID49 protein 20130415 {GO:0005515=IPI, GO:0005741=IDA, GO:0007005=IDA, GO:0016021=IEA} mitochondrion organization integral to membrane, mitochondrial outer membrane protein binding Human UniProtKB:Q9UI14 SMCR7L LIFEdb UniProtKB {GO:0005515=PMID:21701560, GO:0005739=GO_REF:0000054, GO:0008053=PMID:21701560, GO:0005741=PMID:21701560, GO:0016021=GO_REF:0000037} Q9NQG6 Mitochondrial dynamic protein MID51 protein 20100607 {GO:0005515=IPI, GO:0005739=IDA, GO:0008053=IMP, GO:0005741=IDA, GO:0016021=IEA} mitochondrial fusion integral to membrane, mitochondrial outer membrane, mitochondrion protein binding Human SMCR8 HPA UniProtKB {GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q8TEV9 Smith-Magenis syndrome chromosomal region candidate gene 8 protein protein 20100326 {GO:0005730=IDA, GO:0005634=IDA} nucleolus, nucleus NOT Human SMEK1 UniProtKB UniProtKB {GO:0030289=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0006470=GO_REF:0000019, GO:0005815=GO_REF:0000039, GO:0045722=GO_REF:0000019, GO:0005634=GO_REF:0000039} Q6IN85 Serine/threonine-protein phosphatase 4 regulatory subunit 3A protein 20130413 {GO:0030289=IEA, GO:0005737=IEA, GO:0006470=IEA, GO:0005815=IEA, GO:0045722=IEA, GO:0005634=IEA} positive regulation of gluconeogenesis, protein dephosphorylation cytoplasm, microtubule organizing center, nucleus, protein phosphatase 4 complex Human UniProtKB-SubCell:SL-0048 SMEK2 HPA UniProtKB {GO:0030289=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0006470=GO_REF:0000019, GO:0005815=GO_REF:0000039, GO:0045722=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q5MIZ7 Serine/threonine-protein phosphatase 4 regulatory subunit 3B protein 20120912 {GO:0030289=IEA, GO:0005737=IEA, GO:0006470=IEA, GO:0005815=IEA, GO:0045722=IEA, GO:0005730=IDA, GO:0005634=IDA} positive regulation of gluconeogenesis, protein dephosphorylation cytoplasm, microtubule organizing center, nucleolus, nucleus, protein phosphatase 4 complex NOT Human SMG1 IntAct UniProtKB {GO:0005515=PMID:16452507, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0006950=PMID:15175154, GO:0005634=PMID:14636577, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_75910, GO:0046854=PMID:11331269, GO:0005737=PMID:14636577, GO:0006281=GO_REF:0000037, GO:0046777=PMID:11331269, GO:0006406=PMID:16488880, GO:0004672=PMID:14636577, GO:0000184=Reactome:REACT_75886, GO:0018105=PMID:14636577, GO:0016301=GO_REF:0000038, GO:0004674=Reactome:REACT_75910, GO:0016773=GO_REF:0000002} Q96Q15 Serine/threonine-protein kinase SMG1 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0006950=IDA, GO:0005634=IDA, GO:0005524=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0046854=IDA, GO:0005737=IDA, GO:0006281=IEA, GO:0046777=IDA, GO:0006406=TAS, GO:0004672=TAS, GO:0000184=TAS, GO:0018105=TAS, GO:0016301=IEA, GO:0004674=EXP, GO:0016773=IEA} DNA repair, RNA metabolic process, gene expression, mRNA export from nucleus, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, peptidyl-serine phosphorylation, phosphatidylinositol phosphorylation, protein autophosphorylation, response to stress cytoplasm, cytosol, nucleus ATP binding, kinase activity, metal ion binding, phosphotransferase activity, alcohol group as acceptor, protein binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB:P11940 SMG5 IntAct UniProtKB {GO:0005515=PMID:21145460, GO:0010467=Reactome:REACT_71, GO:0035303=PMID:14636577, GO:0005737=PMID:14636577, GO:0006406=PMID:16488880, GO:0016070=Reactome:REACT_21257, GO:0000184=Reactome:REACT_75886, GO:0016071=Reactome:REACT_20605, GO:0005634=PMID:14636577, GO:0051721=PMID:14636577, GO:0005829=Reactome:REACT_75891} Q9UPR3 Protein SMG5 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0035303=IMP, GO:0005737=IDA, GO:0006406=TAS, GO:0016070=TAS, GO:0000184=TAS, GO:0016071=TAS, GO:0005634=IDA, GO:0051721=IDA, GO:0005829=TAS} RNA metabolic process, gene expression, mRNA export from nucleus, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, regulation of dephosphorylation cytoplasm, cytosol, nucleus protein binding, protein phosphatase 2A binding Human UniProtKB:Q92900-2 SMG6 HPA UniProtKB {GO:0005515=PMID:21145460, GO:0010467=Reactome:REACT_71, GO:0000781=GO_REF:0000039, GO:0005697=PMID:12699629, GO:0035303=PMID:15721257, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0042162=PMID:12699629, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0004521=Reactome:REACT_75787, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_75891, GO:0005737=GO_REF:0000052, GO:0006406=PMID:16488880, GO:0000184=Reactome:REACT_75886, GO:0000723=PMID:12699629} Q86US8 Telomerase-binding protein EST1A protein 20111111 {GO:0005515=IPI, GO:0010467=TAS, GO:0000781=IEA, GO:0005697=TAS, GO:0035303=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0042162=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0004521=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0006406=TAS, GO:0000184=TAS, GO:0000723=IMP} RNA metabolic process, gene expression, mRNA export from nucleus, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, regulation of dephosphorylation, telomere maintenance chromosome, telomeric region, cytoplasm, cytosol, nucleolus, nucleus, telomerase holoenzyme complex endoribonuclease activity, metal ion binding, protein binding, telomeric DNA binding Human SMG7 HPA UniProtKB {GO:0005515=PMID:14636577, GO:0010467=Reactome:REACT_71, GO:0035303=PMID:15721257, GO:0005737=GO_REF:0000052, GO:0006406=PMID:16488880, GO:0016070=Reactome:REACT_21257, GO:0000184=Reactome:REACT_75886, GO:0016071=Reactome:REACT_20605, GO:0005634=PMID:14636577, GO:0045111=GO_REF:0000052, GO:0051721=PMID:14636577, GO:0005829=Reactome:REACT_75891} Q92540 Protein SMG7 protein 20101115 {GO:0005515=IPI, GO:0010467=TAS, GO:0035303=TAS, GO:0005737=IDA, GO:0006406=TAS, GO:0016070=TAS, GO:0000184=TAS, GO:0016071=TAS, GO:0005634=IDA, GO:0045111=IDA, GO:0051721=IDA, GO:0005829=TAS} RNA metabolic process, gene expression, mRNA export from nucleus, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, regulation of dephosphorylation cytoplasm, cytosol, intermediate filament cytoskeleton, nucleus protein binding, protein phosphatase 2A binding Human SMG8 IntAct UniProtKB {GO:0005515=PMID:20817927, GO:0045859=PMID:19417104, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0000184=Reactome:REACT_75886, GO:0016071=Reactome:REACT_20605, GO:0005575=GO_REF:0000015, GO:0005829=Reactome:REACT_75753} Q8ND04 Protein SMG8 protein 20130415 {GO:0005515=IPI, GO:0045859=IMP, GO:0010467=TAS, GO:0016070=TAS, GO:0000184=TAS, GO:0016071=TAS, GO:0005575=ND, GO:0005829=TAS} RNA metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, regulation of protein kinase activity cellular_component, cytosol protein binding Human UniProtKB:Q9H0W8 SMG9 IntAct UniProtKB {GO:0005622=GO_REF:0000054, GO:0005515=PMID:20817927, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0000184=Reactome:REACT_75886, GO:0016071=Reactome:REACT_20605, GO:0042802=PMID:20817927, GO:0005829=Reactome:REACT_75910} Q9H0W8 Protein SMG9 protein 20130415 {GO:0005622=IDA, GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0000184=TAS, GO:0016071=TAS, GO:0042802=IPI, GO:0005829=TAS} RNA metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay cytosol, intracellular identical protein binding, protein binding Human UniProtKB:Q9H0W8 SMN1 IntAct UniProtKB {GO:0006397=GO_REF:0000002, GO:0005515=PMID:21816274, GO:0008219=GO_REF:0000037, GO:0000245=PMID:9845364, GO:0010467=Reactome:REACT_71, GO:0015030=PMID:9845364, GO:0016070=Reactome:REACT_21257, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000002, GO:0034660=Reactome:REACT_11052, GO:0000387=Reactome:REACT_11066, GO:0005829=Reactome:REACT_10041, GO:0005737=PMID:9845364, GO:0005681=GO_REF:0000037, GO:0005654=Reactome:REACT_10010} Q16637 Survival motor neuron protein protein 20130415 {GO:0006397=IEA, GO:0005515=IPI, GO:0008219=IEA, GO:0000245=NAS, GO:0010467=TAS, GO:0015030=NAS, GO:0016070=TAS, GO:0003723=IEA, GO:0005634=IEA, GO:0034660=TAS, GO:0000387=TAS, GO:0005829=TAS, GO:0005737=NAS, GO:0005681=IEA, GO:0005654=TAS} RNA metabolic process, cell death, gene expression, mRNA processing, ncRNA metabolic process, spliceosomal complex assembly, spliceosomal snRNP assembly Cajal body, cytoplasm, cytosol, nucleoplasm, nucleus, spliceosomal complex RNA binding, protein binding Human UniProtKB:O14893 SMN2 null null {} null null null null {} null null null SMNDC1 IntAct UniProtKB {GO:0005515=PMID:15494309, GO:0008380=PMID:9731529, GO:0006397=GO_REF:0000037, GO:0005737=GO_REF:0000002, GO:0015030=GO_REF:0000039, GO:0016607=GO_REF:0000039, GO:0000375=PMID:9731529, GO:0003723=GO_REF:0000002, GO:0006915=GO_REF:0000037, GO:0005634=PMID:9817934, GO:0005681=GO_REF:0000037, GO:0006917=PMID:9817934} O75940 Survival of motor neuron-related-splicing factor 30 protein 20130415 {GO:0005515=IPI, GO:0008380=TAS, GO:0006397=IEA, GO:0005737=IEA, GO:0015030=IEA, GO:0016607=IEA, GO:0000375=TAS, GO:0003723=IEA, GO:0006915=IEA, GO:0005634=TAS, GO:0005681=IEA, GO:0006917=TAS} RNA splicing, RNA splicing, via transesterification reactions, apoptotic process, induction of apoptosis, mRNA processing Cajal body, cytoplasm, nuclear speck, nucleus, spliceosomal complex RNA binding, protein binding Human UniProtKB:Q14974 SMO BHF-UCL UniProtKB {GO:0005515=PMID:19592253, GO:0008406=GO_REF:0000033, GO:0017147=GO_REF:0000033, GO:0034504=GO_REF:0000019, GO:0060248=PMID:9422511, GO:0021696=GO_REF:0000033, GO:0001755=GO_REF:0000033, GO:0007228=GO_REF:0000024, GO:0048752=GO_REF:0000033, GO:0048703=GO_REF:0000033, GO:0007283=GO_REF:0000033, GO:0048846=GO_REF:0000033, GO:0048702=GO_REF:0000033, GO:0005113=PMID:9811851, GO:0043231=PMID:11278759, GO:0031069=GO_REF:0000019, GO:0042693=GO_REF:0000033, GO:0007224=PMID:9422511, GO:0001947=GO_REF:0000024, GO:0031076=GO_REF:0000033, GO:0003140=GO_REF:0000024, GO:0071397=GO_REF:0000024, GO:0060644=GO_REF:0000019, GO:0043025=GO_REF:0000033, GO:0021561=GO_REF:0000033, GO:0050679=GO_REF:0000033, GO:0060684=GO_REF:0000019, GO:0005794=PMID:11278759, GO:0001708=GO_REF:0000019, GO:0004930=GO_REF:0000037, GO:0021938=GO_REF:0000033, GO:2000826=GO_REF:0000024, GO:0007275=GO_REF:0000038, GO:0003323=GO_REF:0000019, GO:0072372=PMID:21931618, GO:0061113=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0007371=GO_REF:0000024, GO:0030165=GO_REF:0000033, GO:0001701=GO_REF:0000019, GO:0001649=GO_REF:0000033, GO:2000036=GO_REF:0000019, GO:0043392=GO_REF:0000024, GO:0005929=GO_REF:0000033, GO:0061053=GO_REF:0000024, GO:0005119=PMID:22228099, GO:0051799=GO_REF:0000019, GO:0072285=GO_REF:0000024, GO:0010002=GO_REF:0000033, GO:0042307=GO_REF:0000019, GO:0072001=PMID:17850284, GO:0021984=GO_REF:0000033, GO:0007368=GO_REF:0000033, GO:0005886=PMID:19304771, GO:0031102=GO_REF:0000033, GO:0032474=GO_REF:0000033, GO:0060830=GO_REF:0000033, GO:0045880=GO_REF:0000033, GO:0005737=GO_REF:0000033, GO:0035264=GO_REF:0000019, GO:0030857=GO_REF:0000019, GO:0008144=PMID:21177415, GO:0045944=GO_REF:0000019, GO:0042475=GO_REF:0000033, GO:0021904=GO_REF:0000033, GO:0060070=GO_REF:0000033, GO:0090190=GO_REF:0000024, GO:0042813=GO_REF:0000033, GO:0043066=GO_REF:0000033, GO:0050821=GO_REF:0000019, GO:0021508=GO_REF:0000033, GO:0021953=GO_REF:0000033, GO:0002052=GO_REF:0000033, GO:0002053=GO_REF:0000033, GO:0048663=GO_REF:0000033, GO:0048853=GO_REF:0000024, GO:0010628=GO_REF:0000024, GO:0003007=GO_REF:0000033, GO:0021910=GO_REF:0000033, GO:0048557=GO_REF:0000033, GO:0007494=GO_REF:0000024, GO:0010629=GO_REF:0000024, GO:0031017=GO_REF:0000033, GO:0016021=GO_REF:0000037, GO:0001570=GO_REF:0000033} Q99835 Smoothened homolog protein 20111121 {GO:0005515=IPI, GO:0008406=IBA, GO:0017147=IBA, GO:0034504=IEA, GO:0060248=IMP, GO:0021696=IBA, GO:0001755=IBA, GO:0007228=ISS, GO:0048752=IBA, GO:0048703=IBA, GO:0007283=IBA, GO:0048846=IBA, GO:0048702=IBA, GO:0005113=IPI, GO:0043231=IDA, GO:0031069=IEA, GO:0042693=IBA, GO:0007224=IMP, GO:0001947=ISS, GO:0031076=IBA, GO:0003140=ISS, GO:0071397=ISS, GO:0060644=IEA, GO:0043025=IBA, GO:0021561=IBA, GO:0050679=IBA, GO:0060684=IEA, GO:0005794=IDA, GO:0001708=IEA, GO:0004930=IEA, GO:0021938=IBA, GO:2000826=ISS, GO:0007275=IEA, GO:0003323=IEA, GO:0072372=TAS, GO:0061113=IEA, GO:0000122=IEA, GO:0007371=ISS, GO:0030165=IBA, GO:0001701=IEA, GO:0001649=IBA, GO:2000036=IEA, GO:0043392=ISS, GO:0005929=IBA, GO:0061053=ISS, GO:0005119=IPI, GO:0051799=IEA, GO:0072285=ISS, GO:0010002=IBA, GO:0042307=IEA, GO:0072001=IEP, GO:0021984=IBA, GO:0007368=IBA, GO:0005886=IDA, GO:0031102=IBA, GO:0032474=IBA, GO:0060830=IBA, GO:0045880=IBA, GO:0005737=IBA, GO:0035264=IEA, GO:0030857=IEA, GO:0008144=IDA, GO:0045944=IEA, GO:0042475=IBA, GO:0021904=IBA, GO:0060070=IBA, GO:0090190=ISS, GO:0042813=IBA, GO:0043066=IBA, GO:0050821=IEA, GO:0021508=IBA, GO:0021953=IBA, GO:0002052=IBA, GO:0002053=IBA, GO:0048663=IBA, GO:0048853=ISS, GO:0010628=ISS, GO:0003007=IBA, GO:0021910=IBA, GO:0048557=IBA, GO:0007494=ISS, GO:0010629=ISS, GO:0031017=IBA, GO:0016021=IEA, GO:0001570=IBA} adenohypophysis development, axon extension involved in axon guidance, canonical Wnt receptor signaling pathway, cardioblast differentiation, cell fate specification, cellular response to cholesterol, central nervous system neuron differentiation, cerebellar cortex morphogenesis, ciliary receptor clustering involved in smoothened signaling pathway, detection of cell density by contact stimulus involved in contact inhibition, determination of left/right asymmetry in lateral mesoderm, determination of left/right symmetry, dorsal/ventral neural tube patterning, embryonic camera-type eye development, embryonic digestive tract morphogenesis, embryonic neurocranium morphogenesis, embryonic viscerocranium morphogenesis, epithelial-mesenchymal cell signaling, exocrine pancreas development, facial nerve development, floor plate formation, forebrain morphogenesis, gonad development, hair follicle morphogenesis, heart looping, heart morphogenesis, in utero embryonic development, mammary gland epithelial cell differentiation, mesenchymal to epithelial transition involved in metanephric renal vesicle formation, midgut development, multicellular organism growth, multicellular organismal development, muscle cell fate commitment, negative regulation of DNA binding, negative regulation of apoptotic process, negative regulation of epithelial cell differentiation, negative regulation of gene expression, negative regulation of hair follicle development, negative regulation of transcription from RNA polymerase II promoter, neural crest cell migration, neuron fate commitment, neuron projection regeneration, odontogenesis of dentin-containing tooth, osteoblast differentiation, otolith morphogenesis, pancreas morphogenesis, positive regulation of branching involved in ureteric bud morphogenesis, positive regulation of epithelial cell proliferation, positive regulation of gene expression, positive regulation of hh target transcription factor activity, positive regulation of mesenchymal cell proliferation, positive regulation of neuroblast proliferation, positive regulation of protein import into nucleus, positive regulation of smoothened signaling pathway, positive regulation of transcription from RNA polymerase II promoter, protein localization to nucleus, protein stabilization, regulation of heart morphogenesis, regulation of stem cell maintenance, renal system development, semicircular canal morphogenesis, smoothened signaling pathway, smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation, smoothened signaling pathway involved in ventral spinal cord patterning, somite development, spermatogenesis, type B pancreatic cell development, vasculogenesis, ventral midline determination Golgi apparatus, cilium, cytoplasm, integral to membrane, intracellular membrane-bounded organelle, neuronal cell body, plasma membrane, primary cilium G-protein coupled receptor activity, PDZ domain binding, Wnt-activated receptor activity, Wnt-protein binding, drug binding, patched binding, protein binding, smoothened binding Human SMOC1 IntAct UniProtKB {GO:0005515=PMID:23088713, GO:0007165=GO_REF:0000002, GO:0045667=PMID:20359165, GO:0030198=GO_REF:0000019, GO:0001654=PMID:21194678, GO:0010811=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0050840=GO_REF:0000019, GO:0060173=PMID:21194678, GO:0030154=GO_REF:0000037, GO:0005604=GO_REF:0000039} Q9H4F8 SPARC-related modular calcium-binding protein 1 protein 20130415 {GO:0005515=IPI, GO:0007165=IEA, GO:0045667=IMP, GO:0030198=IEA, GO:0001654=IMP, GO:0010811=IEA, GO:0005509=IEA, GO:0050840=IEA, GO:0060173=IMP, GO:0030154=IEA, GO:0005604=IEA} cell differentiation, extracellular matrix organization, eye development, limb development, positive regulation of cell-substrate adhesion, regulation of osteoblast differentiation, signal transduction basement membrane calcium ion binding, extracellular matrix binding, protein binding Human UniProtKB:P09022 SMOC2 UniProtKB UniProtKB {GO:0007165=GO_REF:0000002, GO:0030198=GO_REF:0000019, GO:0010811=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0005578=GO_REF:0000002, GO:0005614=GO_REF:0000019, GO:0008201=GO_REF:0000019, GO:0005604=GO_REF:0000039} Q9H3U7 SPARC-related modular calcium-binding protein 2 protein 20130413 {GO:0007165=IEA, GO:0030198=IEA, GO:0010811=IEA, GO:0005509=IEA, GO:0005578=IEA, GO:0005614=IEA, GO:0008201=IEA, GO:0005604=IEA} extracellular matrix organization, positive regulation of cell-substrate adhesion, signal transduction basement membrane, interstitial matrix, proteinaceous extracellular matrix calcium ion binding, heparin binding Human UniProtKB-SubCell:SL-0025 SMOX HPA UniProtKB {GO:0052901=GO_REF:0000003, GO:0006805=Reactome:REACT_13705, GO:0005634=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_2194, GO:0046592=PMID:12477380, GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000052, GO:0006598=PMID:12477380, GO:0006596=Reactome:REACT_14805, GO:0006595=Reactome:REACT_14820, GO:0016491=GO_REF:0000002, GO:0052895=GO_REF:0000003, GO:0052894=GO_REF:0000003, GO:0046208=GO_REF:0000041} Q9NWM0 Spermine oxidase protein 20111111 {GO:0052901=IEA, GO:0006805=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0005829=TAS, GO:0046592=IDA, GO:0034641=TAS, GO:0005737=IDA, GO:0006598=IDA, GO:0006596=TAS, GO:0006595=TAS, GO:0016491=IEA, GO:0052895=IEA, GO:0052894=IEA, GO:0046208=IEA} cellular nitrogen compound metabolic process, polyamine biosynthetic process, polyamine catabolic process, polyamine metabolic process, small molecule metabolic process, spermine catabolic process, xenobiotic metabolic process cytoplasm, cytosol, nucleus N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity, norspermine:oxygen oxidoreductase activity, oxidoreductase activity, polyamine oxidase activity, spermine:oxygen oxidoreductase (spermidine-forming) activity Human SMPD1 BHF-UCL UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0008219=GO_REF:0000037, GO:0006685=GO_REF:0000002, GO:0043065=GO_REF:0000019, GO:0006684=PMID:7670466, GO:0006687=Reactome:REACT_116105, GO:0035307=PMID:19279008, GO:0042493=GO_REF:0000019, GO:0004767=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0042220=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0007399=PMID:7670466, GO:0007165=PMID:7670466, GO:0016787=GO_REF:0000002, GO:0043407=PMID:19279008, GO:0042599=GO_REF:0000019, GO:0016798=GO_REF:0000037, GO:0046513=PMID:19279011, GO:0023021=PMID:19279008, GO:0043202=Reactome:REACT_116148} P17405 Sphingomyelin phosphodiesterase protein 20110617 {GO:0006665=TAS, GO:0008219=IEA, GO:0006685=IEA, GO:0043065=IEA, GO:0006684=TAS, GO:0006687=TAS, GO:0035307=IMP, GO:0042493=IEA, GO:0004767=IEA, GO:0044281=TAS, GO:0042220=IEA, GO:0005615=IEA, GO:0007399=TAS, GO:0007165=TAS, GO:0016787=IEA, GO:0043407=IMP, GO:0042599=IEA, GO:0016798=IEA, GO:0046513=IMP, GO:0023021=IMP, GO:0043202=TAS} cell death, ceramide biosynthetic process, glycosphingolipid metabolic process, negative regulation of MAP kinase activity, nervous system development, positive regulation of apoptotic process, positive regulation of protein dephosphorylation, response to cocaine, response to drug, signal transduction, small molecule metabolic process, sphingolipid metabolic process, sphingomyelin catabolic process, sphingomyelin metabolic process, termination of signal transduction extracellular space, lamellar body, lysosomal lumen hydrolase activity, hydrolase activity, acting on glycosyl bonds, sphingomyelin phosphodiesterase activity Human SMPD2 Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0048011=Reactome:REACT_13776, GO:0006684=PMID:9520418, GO:0005886=Reactome:REACT_115857, GO:0006687=Reactome:REACT_116105, GO:0004767=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0097190=Reactome:REACT_13806, GO:0046872=GO_REF:0000037, GO:0007243=GO_REF:0000019, GO:0009612=GO_REF:0000019, GO:0005887=PMID:9520418, GO:0005901=GO_REF:0000019, GO:0046513=GO_REF:0000019} O60906 Sphingomyelin phosphodiesterase 2 protein 20111031 {GO:0006665=TAS, GO:0048011=TAS, GO:0006684=TAS, GO:0005886=TAS, GO:0006687=TAS, GO:0004767=IEA, GO:0044281=TAS, GO:0097190=TAS, GO:0046872=IEA, GO:0007243=IEA, GO:0009612=IEA, GO:0005887=TAS, GO:0005901=IEA, GO:0046513=IEA} apoptotic signaling pathway, ceramide biosynthetic process, glycosphingolipid metabolic process, intracellular protein kinase cascade, neurotrophin TRK receptor signaling pathway, response to mechanical stimulus, small molecule metabolic process, sphingolipid metabolic process, sphingomyelin metabolic process caveola, integral to plasma membrane, plasma membrane metal ion binding, sphingomyelin phosphodiesterase activity Human SMPD3 Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0006685=PMID:10823942, GO:0006684=GO_REF:0000019, GO:0005886=Reactome:REACT_115857, GO:0006687=Reactome:REACT_116105, GO:0004767=GO_REF:0000003, GO:0007275=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0000137=GO_REF:0000019, GO:0007049=GO_REF:0000037, GO:0000139=GO_REF:0000039, GO:0030072=GO_REF:0000019} Q9NY59 Sphingomyelin phosphodiesterase 3 protein 20130301 {GO:0006665=TAS, GO:0006685=TAS, GO:0006684=IEA, GO:0005886=TAS, GO:0006687=TAS, GO:0004767=IEA, GO:0007275=IEA, GO:0044281=TAS, GO:0046872=IEA, GO:0000137=IEA, GO:0007049=IEA, GO:0000139=IEA, GO:0030072=IEA} cell cycle, glycosphingolipid metabolic process, multicellular organismal development, peptide hormone secretion, small molecule metabolic process, sphingolipid metabolic process, sphingomyelin catabolic process, sphingomyelin metabolic process Golgi cis cisterna, Golgi membrane, plasma membrane metal ion binding, sphingomyelin phosphodiesterase activity Human SMPD4 BHF-UCL UniProtKB {GO:0005802=PMID:16517606, GO:0006665=Reactome:REACT_19323, GO:0006685=PMID:16517606, GO:0005794=PMID:16517606, GO:0006687=Reactome:REACT_116105, GO:0005783=PMID:18505924, GO:0004767=Reactome:REACT_116064, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0000139=GO_REF:0000039, GO:0071356=PMID:16517606, GO:0005789=Reactome:REACT_116064, GO:0050290=PMID:16517606, GO:0016021=GO_REF:0000037, GO:0046475=PMID:16517606, GO:0046513=PMID:16517606} Q9NXE4 Sphingomyelin phosphodiesterase 4 protein 20110722 {GO:0005802=IDA, GO:0006665=TAS, GO:0006685=IDA, GO:0005794=IDA, GO:0006687=TAS, GO:0005783=IDA, GO:0004767=TAS, GO:0044281=TAS, GO:0046872=IEA, GO:0000139=IEA, GO:0071356=IDA, GO:0005789=TAS, GO:0050290=IDA, GO:0016021=IEA, GO:0046475=IDA, GO:0046513=IDA} cellular response to tumor necrosis factor, ceramide biosynthetic process, glycerophospholipid catabolic process, glycosphingolipid metabolic process, small molecule metabolic process, sphingolipid metabolic process, sphingomyelin catabolic process Golgi apparatus, Golgi membrane, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, trans-Golgi network metal ion binding, sphingomyelin phosphodiesterase D activity, sphingomyelin phosphodiesterase activity Human SMPDL3A UniProtKB UniProtKB {GO:0005515=PMID:12442002, GO:0008150=GO_REF:0000015, GO:0006685=GO_REF:0000002, GO:0016787=GO_REF:0000002, GO:0016798=GO_REF:0000037, GO:0004767=GO_REF:0000002, GO:0005576=GO_REF:0000029, GO:0005615=GO_REF:0000002} Q92484 Acid sphingomyelinase-like phosphodiesterase 3a protein 20050114 {GO:0005515=IPI, GO:0008150=ND, GO:0006685=IEA, GO:0016787=IEA, GO:0016798=IEA, GO:0004767=IEA, GO:0005576=NAS, GO:0005615=IEA} biological_process, sphingomyelin catabolic process extracellular region, extracellular space hydrolase activity, hydrolase activity, acting on glycosyl bonds, protein binding, sphingomyelin phosphodiesterase activity Human SMR3B PINC UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005615=PMID:7982889} P02814 Submaxillary gland androgen-regulated protein 3B protein 20050308 {GO:0008150=ND, GO:0003674=ND, GO:0005615=TAS} biological_process extracellular space molecular_function Human SMS Reactome UniProtKB {GO:0034641=Reactome:REACT_13, GO:0004766=PMID:9299240, GO:0006597=GO_REF:0000041, GO:0006595=Reactome:REACT_14820, GO:0016768=GO_REF:0000003, GO:0006555=PMID:7546290, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_14825} P52788 Spermine synthase protein 20130301 {GO:0034641=TAS, GO:0004766=TAS, GO:0006597=IEA, GO:0006595=TAS, GO:0016768=IEA, GO:0006555=TAS, GO:0044281=TAS, GO:0005829=TAS} cellular nitrogen compound metabolic process, methionine metabolic process, polyamine metabolic process, small molecule metabolic process, spermine biosynthetic process cytosol spermidine synthase activity, spermine synthase activity Human SMTN PINC UniProtKB {GO:0006939=PMID:8707825, GO:0005737=GO_REF:0000037, GO:0007517=PMID:8707825, GO:0003779=PMID:8707825, GO:0015629=PMID:8707825, GO:0008307=PMID:8707825, GO:0005856=PMID:8707825} P53814 Smoothelin protein 20030904 {GO:0006939=TAS, GO:0005737=IEA, GO:0007517=TAS, GO:0003779=TAS, GO:0015629=TAS, GO:0008307=TAS, GO:0005856=TAS} muscle organ development, smooth muscle contraction actin cytoskeleton, cytoplasm, cytoskeleton actin binding, structural constituent of muscle Human SMTNL2 null null {} null null null null {} null null null SMU1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039} Q2TAY7 WD40 repeat-containing protein SMU1 protein 20130413 {GO:0005737=IEA, GO:0005634=IEA} cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 SMUG1 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0004844=PMID:12718543, GO:0019104=PMID:11526119, GO:0006281=Reactome:REACT_216, GO:0017065=PMID:12718543, GO:0006284=Reactome:REACT_1104, GO:0045008=Reactome:REACT_2156, GO:0006285=Reactome:REACT_804, GO:0005730=PMID:12161446, GO:0005654=Reactome:REACT_2205, GO:0003677=GO_REF:0000037} Q53HV7 Single-strand selective monofunctional uracil DNA glycosylase protein 20130415 {GO:0005515=IPI, GO:0004844=IDA, GO:0019104=IDA, GO:0006281=TAS, GO:0017065=IDA, GO:0006284=TAS, GO:0045008=TAS, GO:0006285=TAS, GO:0005730=IDA, GO:0005654=TAS, GO:0003677=IEA} DNA repair, base-excision repair, base-excision repair, AP site formation, depyrimidination nucleolus, nucleoplasm DNA N-glycosylase activity, DNA binding, protein binding, single-strand selective uracil DNA N-glycosylase activity, uracil DNA N-glycosylase activity Human UniProtKB:Q93062 SMURF1 BHF-UCL UniProtKB {GO:0005515=PMID:21572392, GO:0004842=PMID:12151385, GO:0016567=PMID:11278251, GO:0005886=PMID:12151385, GO:0005634=GO_REF:0000033, GO:0030154=PMID:10458166, GO:0005829=Reactome:REACT_121376, GO:0030514=PMID:10458166, GO:0005737=PMID:12151385, GO:0030279=GO_REF:0000019, GO:0042787=PMID:12151385, GO:0048185=PMID:16720724, GO:0006611=PMID:11278251, GO:0031398=PMID:16720724, GO:0043025=GO_REF:0000019, GO:0007179=Reactome:REACT_120850, GO:0030579=PMID:12151385, GO:0030512=PMID:12151385, GO:0000209=PMID:19937093, GO:0070411=PMID:16720724, GO:0070412=PMID:11278251, GO:0030509=Reactome:REACT_12034, GO:0007398=PMID:10458166, GO:0033267=GO_REF:0000019, GO:0032801=PMID:12151385, GO:0034394=PMID:12151385, GO:0005654=Reactome:REACT_121294, GO:0043161=PMID:11278251} Q9HCE7 E3 ubiquitin-protein ligase SMURF1 protein 20090108 {GO:0005515=IPI, GO:0004842=IDA, GO:0016567=IDA, GO:0005886=IDA, GO:0005634=IBA, GO:0030154=IDA, GO:0005829=TAS, GO:0030514=TAS, GO:0005737=IDA, GO:0030279=IEA, GO:0042787=IDA, GO:0048185=IPI, GO:0006611=IDA, GO:0031398=IDA, GO:0043025=IEA, GO:0007179=TAS, GO:0030579=IDA, GO:0030512=IDA, GO:0000209=IDA, GO:0070411=IPI, GO:0070412=IPI, GO:0030509=TAS, GO:0007398=TAS, GO:0033267=IEA, GO:0032801=IDA, GO:0034394=IDA, GO:0005654=TAS, GO:0043161=IDA} BMP signaling pathway, cell differentiation, ectoderm development, negative regulation of BMP signaling pathway, negative regulation of ossification, negative regulation of transforming growth factor beta receptor signaling pathway, positive regulation of protein ubiquitination, proteasomal ubiquitin-dependent protein catabolic process, protein export from nucleus, protein localization to cell surface, protein polyubiquitination, protein ubiquitination, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, receptor catabolic process, transforming growth factor beta receptor signaling pathway, ubiquitin-dependent SMAD protein catabolic process axon part, cytoplasm, cytosol, neuronal cell body, nucleoplasm, nucleus, plasma membrane I-SMAD binding, R-SMAD binding, activin binding, protein binding, ubiquitin-protein ligase activity Human UniProtKB:P36896 SMURF2 BHF-UCL UniProtKB {GO:0005515=PMID:20676133, GO:0006511=PMID:14755250, GO:0010467=Reactome:REACT_71, GO:0004842=Reactome:REACT_120960, GO:0006367=Reactome:REACT_12627, GO:0005886=GO_REF:0000039, GO:0000151=PMID:14755250, GO:0005634=PMID:11163210, GO:0046332=PMID:19122240, GO:0005829=Reactome:REACT_121290, GO:0042802=PMID:17719543, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000033, GO:0042787=GO_REF:0000033, GO:0007179=Reactome:REACT_120850, GO:0017015=PMID:11158580, GO:0030579=PMID:19122240, GO:0030512=Reactome:REACT_120727, GO:0000122=Reactome:REACT_121111, GO:0030509=Reactome:REACT_12034, GO:0005160=GO_REF:0000019, GO:0006351=Reactome:REACT_121061, GO:0005654=Reactome:REACT_121396, GO:0045121=GO_REF:0000039, GO:0045892=PMID:11016919} Q9HAU4 E3 ubiquitin-protein ligase SMURF2 protein 20100310 {GO:0005515=IPI, GO:0006511=IDA, GO:0010467=TAS, GO:0004842=TAS, GO:0006367=TAS, GO:0005886=IEA, GO:0000151=IDA, GO:0005634=NAS, GO:0046332=IPI, GO:0005829=TAS, GO:0042802=IPI, GO:0005622=IEA, GO:0005737=IBA, GO:0042787=IBA, GO:0007179=TAS, GO:0017015=NAS, GO:0030579=IDA, GO:0030512=TAS, GO:0000122=TAS, GO:0030509=TAS, GO:0005160=IEA, GO:0006351=TAS, GO:0005654=TAS, GO:0045121=IEA, GO:0045892=NAS} BMP signaling pathway, gene expression, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, negative regulation of transforming growth factor beta receptor signaling pathway, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, regulation of transforming growth factor beta receptor signaling pathway, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, ubiquitin-dependent SMAD protein catabolic process, ubiquitin-dependent protein catabolic process cytoplasm, cytosol, intracellular, membrane raft, nucleoplasm, nucleus, plasma membrane, ubiquitin ligase complex SMAD binding, identical protein binding, protein binding, transforming growth factor beta receptor binding, ubiquitin-protein ligase activity Human UniProtKB:Q15796 SMYD1 BHF-UCL UniProtKB {GO:0007507=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0045663=PMID:19783823, GO:0003714=GO_REF:0000019, GO:0010831=PMID:19783823, GO:0005634=GO_REF:0000039, GO:0006338=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0045892=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8NB12 SET and MYND domain-containing protein 1 protein 20121024 {GO:0007507=IEA, GO:0005737=IEA, GO:0045663=IDA, GO:0003714=IEA, GO:0010831=IDA, GO:0005634=IEA, GO:0006338=IEA, GO:0008270=IEA, GO:0045892=IEA, GO:0003677=IEA, GO:0006351=IEA} chromatin remodeling, heart development, negative regulation of transcription, DNA-dependent, positive regulation of myoblast differentiation, positive regulation of myotube differentiation, transcription, DNA-dependent cytoplasm, nucleus DNA binding, transcription corepressor activity, zinc ion binding Human SMYD2 UniProtKB UniProtKB {GO:0005515=PMID:20870719, GO:0008285=GO_REF:0000024, GO:0000993=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0018027=GO_REF:0000024, GO:0000122=PMID:17108971, GO:0018026=PMID:20870719, GO:0016279=PMID:20870719, GO:0006351=GO_REF:0000037, GO:0005829=GO_REF:0000024, GO:0002039=PMID:17108971, GO:0005737=GO_REF:0000024, GO:0046975=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0043516=PMID:17108971} Q9NRG4 N-lysine methyltransferase SMYD2 protein 20110121 {GO:0005515=IPI, GO:0008285=ISS, GO:0000993=ISS, GO:0005634=ISS, GO:0018027=ISS, GO:0000122=IMP, GO:0018026=IDA, GO:0016279=IDA, GO:0006351=IEA, GO:0005829=ISS, GO:0002039=IPI, GO:0005737=ISS, GO:0046975=ISS, GO:0008270=IEA, GO:0043516=IMP} negative regulation of cell proliferation, negative regulation of transcription from RNA polymerase II promoter, peptidyl-lysine dimethylation, peptidyl-lysine monomethylation, regulation of DNA damage response, signal transduction by p53 class mediator, transcription, DNA-dependent cytoplasm, cytosol, nucleus RNA polymerase II core binding, histone methyltransferase activity (H3-K36 specific), p53 binding, protein binding, protein-lysine N-methyltransferase activity, zinc ion binding Human UniProtKB:Q8R5A0 SMYD3 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0018024=GO_REF:0000024} Q9H7B4 Histone-lysine N-methyltransferase SMYD3 protein 20110121 {GO:0005737=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0018024=ISS} cytoplasm, nucleus histone-lysine N-methyltransferase activity, zinc ion binding Human UniProtKB:Q9CWR2 SMYD5 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0046872=GO_REF:0000037} Q6GMV2 SET and MYND domain-containing protein 5 protein 20061106 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND, GO:0046872=IEA} biological_process cellular_component metal ion binding, molecular_function Human SNAI1 BHF-UCL UniProtKB {GO:0005515=PMID:21577210, GO:2000810=PMID:15314165, GO:0010718=PMID:17072303, GO:0005634=PMID:19955572, GO:0001837=PMID:16096638, GO:0031069=GO_REF:0000019, GO:0005737=PMID:19955572, GO:0061314=GO_REF:0000024, GO:0060972=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:0019900=PMID:15448698, GO:0043066=PMID:15314165, GO:0030335=PMID:15314165, GO:0001707=GO_REF:0000024, GO:0060707=GO_REF:0000019, GO:0000122=PMID:15314165, GO:0060806=GO_REF:0000019, GO:0001649=PMID:20128911, GO:0043565=GO_REF:0000019, GO:0016477=GO_REF:0000019, GO:0043518=PMID:15314165, GO:0008270=GO_REF:0000002, GO:0060536=GO_REF:0000019, GO:0045893=PMID:20018240, GO:0010957=PMID:19502595} O95863 Zinc finger protein SNAI1 protein 20120727 {GO:0005515=IPI, GO:2000810=IMP, GO:0010718=TAS, GO:0005634=IDA, GO:0001837=IDA, GO:0031069=IEA, GO:0005737=IDA, GO:0061314=ISS, GO:0060972=IEA, GO:0060021=IEA, GO:0019900=IPI, GO:0043066=IMP, GO:0030335=IMP, GO:0001707=ISS, GO:0060707=IEA, GO:0000122=IMP, GO:0060806=IEA, GO:0001649=IEP, GO:0043565=IEA, GO:0016477=IEA, GO:0043518=IMP, GO:0008270=IEA, GO:0060536=IEA, GO:0045893=IMP, GO:0010957=IDA} Notch signaling involved in heart development, cartilage morphogenesis, cell migration, epithelial to mesenchymal transition, hair follicle morphogenesis, left/right pattern formation, mesoderm formation, negative regulation of DNA damage response, signal transduction by p53 class mediator, negative regulation of apoptotic process, negative regulation of cell differentiation involved in embryonic placenta development, negative regulation of transcription from RNA polymerase II promoter, negative regulation of vitamin D biosynthetic process, osteoblast differentiation, palate development, positive regulation of cell migration, positive regulation of epithelial to mesenchymal transition, positive regulation of transcription, DNA-dependent, regulation of tight junction assembly, trophoblast giant cell differentiation cytoplasm, nucleus kinase binding, protein binding, sequence-specific DNA binding, zinc ion binding Human UniProtKB:Q02085 SNAI2 BHF-UCL UniProtKB {GO:0010839=PMID:16707493, GO:0033629=PMID:16707493, GO:0035921=PMID:9182671, GO:0000790=PMID:19756381, GO:0060429=PMID:18716062, GO:2000810=PMID:15314165, GO:0007605=PMID:12444107, GO:0003705=GO_REF:0000019, GO:0005634=PMID:10866665, GO:0009790=GO_REF:0000019, GO:0001837=PMID:17984306, GO:2000811=PMID:17984306, GO:0035414=PMID:19502595, GO:0035066=GO_REF:0000019, GO:1900387=PMID:17984306, GO:0005737=GO_REF:0000039, GO:0007219=PMID:18663143, GO:0014032=PMID:12444107, GO:0006933=GO_REF:0000019, GO:0032642=PMID:21182836, GO:0060021=GO_REF:0000019, GO:0032331=PMID:19756381, GO:0090090=PMID:19756381, GO:0060070=PMID:20128911, GO:0043066=PMID:15314165, GO:0030335=PMID:15314165, GO:0003198=GO_REF:0000024, GO:0003273=GO_REF:0000024, GO:2000647=GO_REF:0000019, GO:0000122=PMID:18663143, GO:0044344=GO_REF:0000019, GO:0001649=PMID:20128911, GO:0071479=GO_REF:0000019, GO:0043565=PMID:10518215, GO:0070563=PMID:19502595, GO:0001078=PMID:18663143, GO:0045667=PMID:19756381, GO:0050872=GO_REF:0000019, GO:0071364=PMID:18716062, GO:0003682=GO_REF:0000019, GO:0043473=PMID:12444107, GO:0045600=GO_REF:0000019, GO:0043518=PMID:15314165, GO:0008270=GO_REF:0000002, GO:0060536=GO_REF:0000019, GO:0010957=PMID:19502595} O43623 Zinc finger protein SNAI2 protein 20120727 {GO:0010839=IDA, GO:0033629=IC, GO:0035921=IMP, GO:0000790=IDA, GO:0060429=ISS, GO:2000810=IMP, GO:0007605=IMP, GO:0003705=IEA, GO:0005634=IDA, GO:0009790=IEA, GO:0001837=IMP, GO:2000811=IMP, GO:0035414=IDA, GO:0035066=IEA, GO:1900387=IMP, GO:0005737=IEA, GO:0007219=IMP, GO:0014032=IMP, GO:0006933=IEA, GO:0032642=IMP, GO:0060021=IEA, GO:0032331=IMP, GO:0090090=IMP, GO:0060070=IMP, GO:0043066=IMP, GO:0030335=IMP, GO:0003198=ISS, GO:0003273=ISS, GO:2000647=IEA, GO:0000122=IMP, GO:0044344=IEA, GO:0001649=IEP, GO:0071479=IEA, GO:0043565=IDA, GO:0070563=IDA, GO:0001078=IDA, GO:0045667=IMP, GO:0050872=IEA, GO:0071364=IDA, GO:0003682=IEA, GO:0043473=IMP, GO:0045600=IEA, GO:0043518=IMP, GO:0008270=IEA, GO:0060536=IEA, GO:0010957=IDA} Notch signaling pathway, canonical Wnt receptor signaling pathway, cartilage morphogenesis, cell migration involved in endocardial cushion formation, cellular response to epidermal growth factor stimulus, cellular response to fibroblast growth factor stimulus, cellular response to ionizing radiation, desmosome disassembly, embryo development, epithelial to mesenchymal transition, epithelial to mesenchymal transition involved in endocardial cushion formation, epithelium development, negative regulation of DNA damage response, signal transduction by p53 class mediator, negative regulation of anoikis, negative regulation of apoptotic process, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of catenin import into nucleus, negative regulation of cell adhesion involved in substrate-bound cell migration, negative regulation of cell adhesion mediated by integrin, negative regulation of cell-cell adhesion by negative regulation of transcription from RNA polymerase II promoter, negative regulation of chondrocyte differentiation, negative regulation of keratinocyte proliferation, negative regulation of stem cell proliferation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of vitamin D biosynthetic process, negative regulation of vitamin D receptor signaling pathway, neural crest cell development, osteoblast differentiation, palate development, pigmentation, positive regulation of cell migration, positive regulation of fat cell differentiation, positive regulation of histone acetylation, regulation of chemokine production, regulation of osteoblast differentiation, regulation of tight junction assembly, sensory perception of sound, white fat cell differentiation cytoplasm, nuclear chromatin, nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, chromatin binding, sequence-specific DNA binding, zinc ion binding Human SNAI3 ENSEMBL UniProtKB {GO:0005667=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0005507=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q3KNW1 Zinc finger protein SNAI3 protein 20130413 {GO:0005667=IEA, GO:0003700=IEA, GO:0005507=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} transcription, DNA-dependent transcription factor complex DNA binding, copper ion binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human Ensembl:ENSMUSP00000006762 SNAP23 HPA UniProtKB {GO:0005515=PMID:16189514, GO:0043005=GO_REF:0000039, GO:0005794=GO_REF:0000052, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0042581=PMID:18588921, GO:0006892=Reactome:REACT_11235, GO:0045202=GO_REF:0000037, GO:0042582=PMID:18588921, GO:0005634=GO_REF:0000052, GO:0031410=GO_REF:0000019, GO:0006887=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0006903=PMID:8663154, GO:0006944=PMID:10839363, GO:0016044=Reactome:REACT_11123} O00161 Synaptosomal-associated protein 23 protein 20101115 {GO:0005515=IPI, GO:0043005=IEA, GO:0005794=IDA, GO:0030054=IEA, GO:0005886=IDA, GO:0005730=IDA, GO:0042581=IDA, GO:0006892=TAS, GO:0045202=IEA, GO:0042582=IDA, GO:0005634=IDA, GO:0031410=IEA, GO:0006887=IEA, GO:0015031=IEA, GO:0006903=TAS, GO:0006944=TAS, GO:0016044=TAS} cellular membrane fusion, cellular membrane organization, exocytosis, post-Golgi vesicle-mediated transport, protein transport, vesicle targeting Golgi apparatus, azurophil granule, cell junction, cytoplasmic vesicle, neuron projection, nucleolus, nucleus, plasma membrane, specific granule, synapse protein binding Human SNAP25 Reactome UniProtKB {GO:0005802=GO_REF:0000019, GO:0005515=PMID:11438518, GO:0043005=GO_REF:0000024, GO:0048471=GO_REF:0000039, GO:0016081=PMID:8760387, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_23973, GO:0031201=GO_REF:0000024, GO:0045202=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0014047=Reactome:REACT_12591, GO:0007269=Reactome:REACT_13723, GO:0030426=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0031083=PMID:19546860, GO:0016020=GO_REF:0000024, GO:0000149=GO_REF:0000019, GO:0001504=PMID:8760387, GO:0070032=GO_REF:0000019} P60880 Synaptosomal-associated protein 25 protein 20120104 {GO:0005802=IEA, GO:0005515=IPI, GO:0043005=ISS, GO:0048471=IEA, GO:0016081=NAS, GO:0030054=IEA, GO:0005886=TAS, GO:0031201=ISS, GO:0045202=IEA, GO:0007268=TAS, GO:0044281=TAS, GO:0014047=TAS, GO:0007269=TAS, GO:0030426=ISS, GO:0005737=ISS, GO:0006112=TAS, GO:0050796=TAS, GO:0031083=IDA, GO:0016020=ISS, GO:0000149=IEA, GO:0001504=NAS, GO:0070032=IEA} energy reserve metabolic process, glutamate secretion, neurotransmitter secretion, neurotransmitter uptake, regulation of insulin secretion, small molecule metabolic process, synaptic transmission, synaptic vesicle docking involved in exocytosis BLOC-1 complex, SNARE complex, cell junction, cytoplasm, growth cone, membrane, neuron projection, perinuclear region of cytoplasm, plasma membrane, synapse, synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex, trans-Golgi network SNARE binding, protein binding Human SNAP29 HPA UniProtKB {GO:0000046=PMID:23217709, GO:0043005=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0005886=PMID:9852078, GO:0005730=GO_REF:0000052, GO:0045202=GO_REF:0000037, GO:0031201=PMID:23217709, GO:0005634=GO_REF:0000052, GO:0015031=GO_REF:0000037, GO:0006887=PMID:10839363, GO:0006903=PMID:9852078, GO:0005484=PMID:10839363, GO:0005737=GO_REF:0000052, GO:0006944=PMID:10839363} O95721 Synaptosomal-associated protein 29 protein 20101115 {GO:0000046=IMP, GO:0043005=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0005730=IDA, GO:0045202=IEA, GO:0031201=IDA, GO:0005634=IDA, GO:0015031=IEA, GO:0006887=TAS, GO:0006903=TAS, GO:0005484=TAS, GO:0005737=IDA, GO:0006944=TAS} autophagic vacuole fusion, cellular membrane fusion, exocytosis, protein transport, vesicle targeting SNARE complex, cell junction, cytoplasm, neuron projection, nucleolus, nucleus, plasma membrane, synapse SNAP receptor activity Human SNAP47 UniProtKB UniProtKB {GO:0005515=PMID:19546860, GO:0048471=GO_REF:0000039, GO:0031083=PMID:19546860, GO:0016020=GO_REF:0000037, GO:0012505=GO_REF:0000039} Q5SQN1 Synaptosomal-associated protein 47 protein 20120914 {GO:0005515=IPI, GO:0048471=IEA, GO:0031083=IDA, GO:0016020=IEA, GO:0012505=IEA} BLOC-1 complex, endomembrane system, membrane, perinuclear region of cytoplasm protein binding Human UniProtKB:Q08DU8 SNAP91 UniProtKB UniProtKB {GO:0005545=GO_REF:0000002, GO:0005905=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0030276=GO_REF:0000002, GO:0048268=GO_REF:0000002, GO:0030118=GO_REF:0000002} O60641 Clathrin coat assembly protein AP180 protein 20130413 {GO:0005545=IEA, GO:0005905=IEA, GO:0005543=IEA, GO:0005886=IEA, GO:0030276=IEA, GO:0048268=IEA, GO:0030118=IEA} clathrin coat assembly clathrin coat, coated pit, plasma membrane 1-phosphatidylinositol binding, clathrin binding, phospholipid binding Human UniProtKB-SubCell:SL-0072 SNAPC1 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000037, GO:0005654=Reactome:REACT_1607, GO:0006383=Reactome:REACT_1371, GO:0003677=GO_REF:0000037} Q16533 snRNA-activating protein complex subunit 1 protein 20130213 {GO:0010467=TAS, GO:0006355=IEA, GO:0005654=TAS, GO:0006383=TAS, GO:0003677=IEA} gene expression, regulation of transcription, DNA-dependent, transcription from RNA polymerase III promoter nucleoplasm DNA binding Human SNAPC2 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003700=PMID:8524284, GO:0006366=PMID:8524284, GO:0009301=PMID:8524284, GO:0005654=Reactome:REACT_1607, GO:0005634=PMID:7715707, GO:0006383=Reactome:REACT_1371} Q13487 snRNA-activating protein complex subunit 2 protein 20130213 {GO:0010467=TAS, GO:0003700=TAS, GO:0006366=TAS, GO:0009301=TAS, GO:0005654=TAS, GO:0005634=TAS, GO:0006383=TAS} gene expression, snRNA transcription, transcription from RNA polymerase II promoter, transcription from RNA polymerase III promoter nucleoplasm, nucleus sequence-specific DNA binding transcription factor activity Human SNAPC3 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000037, GO:0009301=PMID:7715707, GO:0006366=PMID:7715707, GO:0005654=Reactome:REACT_1607, GO:0005634=PMID:7715707, GO:0006383=Reactome:REACT_1371, GO:0003677=GO_REF:0000037} Q92966 snRNA-activating protein complex subunit 3 protein 20130213 {GO:0010467=TAS, GO:0006355=IEA, GO:0009301=TAS, GO:0006366=TAS, GO:0005654=TAS, GO:0005634=TAS, GO:0006383=TAS, GO:0003677=IEA} gene expression, regulation of transcription, DNA-dependent, snRNA transcription, transcription from RNA polymerase II promoter, transcription from RNA polymerase III promoter nucleoplasm, nucleus DNA binding Human SNAPC4 Reactome UniProtKB {GO:0042796=PMID:9418884, GO:0010467=Reactome:REACT_71, GO:0003700=PMID:9418884, GO:0009301=PMID:9418884, GO:0006366=PMID:9418884, GO:0003682=GO_REF:0000002, GO:0042795=PMID:9418884, GO:0005654=Reactome:REACT_1607, GO:0005634=PMID:11056176, GO:0006383=Reactome:REACT_1371, GO:0003677=PMID:11056176, GO:0019185=PMID:11056176} Q5SXM2 snRNA-activating protein complex subunit 4 protein 20130213 {GO:0042796=IDA, GO:0010467=TAS, GO:0003700=TAS, GO:0009301=TAS, GO:0006366=TAS, GO:0003682=IEA, GO:0042795=IDA, GO:0005654=TAS, GO:0005634=IC, GO:0006383=TAS, GO:0003677=IDA, GO:0019185=IDA} gene expression, snRNA transcription, snRNA transcription from RNA polymerase II promoter, snRNA transcription from RNA polymerase III promoter, transcription from RNA polymerase II promoter, transcription from RNA polymerase III promoter nucleoplasm, nucleus, snRNA-activating protein complex DNA binding, chromatin binding, sequence-specific DNA binding transcription factor activity Human SNAPC5 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0003700=PMID:9732265, GO:0006366=PMID:9732265, GO:0005654=Reactome:REACT_1607, GO:0005634=PMID:9732265, GO:0006384=PMID:9732265, GO:0006383=Reactome:REACT_1371} O75971 snRNA-activating protein complex subunit 5 protein 20130213 {GO:0010467=TAS, GO:0003700=TAS, GO:0006366=TAS, GO:0005654=TAS, GO:0005634=TAS, GO:0006384=TAS, GO:0006383=TAS} gene expression, transcription from RNA polymerase II promoter, transcription from RNA polymerase III promoter, transcription initiation from RNA polymerase III promoter nucleoplasm, nucleus sequence-specific DNA binding transcription factor activity Human SNAPIN HPA UniProtKB {GO:0005515=PMID:17702749, GO:0043005=GO_REF:0000039, GO:0048490=GO_REF:0000024, GO:0048471=PMID:19168546, GO:0005794=GO_REF:0000052, GO:0030054=GO_REF:0000037, GO:0032438=PMID:22203680, GO:0005730=GO_REF:0000052, GO:0045202=PMID:10195194, GO:0072553=GO_REF:0000019, GO:0016079=PMID:10195194, GO:0006886=PMID:10195194, GO:0007269=PMID:10195194, GO:0031175=GO_REF:0000024, GO:0008021=PMID:10195194, GO:0000139=GO_REF:0000039, GO:0031083=PMID:22203680, GO:0019048=GO_REF:0000037, GO:0000149=PMID:10195194, GO:0016188=GO_REF:0000019, GO:0031629=GO_REF:0000019, GO:0030672=GO_REF:0000039, GO:0008089=GO_REF:0000024} O95295 SNARE-associated protein Snapin protein 20120912 {GO:0005515=IPI, GO:0043005=IEA, GO:0048490=ISS, GO:0048471=IDA, GO:0005794=IDA, GO:0030054=IEA, GO:0032438=NAS, GO:0005730=IDA, GO:0045202=IDA, GO:0072553=IEA, GO:0016079=IDA, GO:0006886=TAS, GO:0007269=TAS, GO:0031175=ISS, GO:0008021=TAS, GO:0000139=IEA, GO:0031083=IDA, GO:0019048=IEA, GO:0000149=IDA, GO:0016188=IEA, GO:0031629=IEA, GO:0030672=IEA, GO:0008089=ISS} anterograde axon cargo transport, anterograde synaptic vesicle transport, intracellular protein transport, melanosome organization, neuron projection development, neurotransmitter secretion, synaptic vesicle exocytosis, synaptic vesicle fusion to presynaptic membrane, synaptic vesicle maturation, terminal button organization, virus-host interaction BLOC-1 complex, Golgi apparatus, Golgi membrane, cell junction, neuron projection, nucleolus, perinuclear region of cytoplasm, synapse, synaptic vesicle, synaptic vesicle membrane SNARE binding, protein binding Human SNCA BHF-UCL UniProtKB {GO:0051219=PMID:21127069, GO:0005515=PMID:11943812, GO:0030054=GO_REF:0000037, GO:0050544=GO_REF:0000019, GO:0031623=PMID:18980610, GO:0043274=GO_REF:0000019, GO:0045963=GO_REF:0000019, GO:0005791=GO_REF:0000019, GO:0006638=GO_REF:0000019, GO:0005504=PMID:16687662, GO:0005794=GO_REF:0000019, GO:0000287=PMID:11850416, GO:0005507=PMID:21320589, GO:0005509=PMID:11850416, GO:0010517=PMID:15641770, GO:0032769=PMID:11943812, GO:0071872=PMID:21320589, GO:0042775=GO_REF:0000019, GO:0051612=PMID:16882008, GO:0007006=GO_REF:0000019, GO:0008270=PMID:11850416, GO:0006644=GO_REF:0000019, GO:0071280=PMID:21320589, GO:0008344=GO_REF:0000019, GO:0030424=PMID:12958153, GO:0048471=PMID:20039155, GO:0071902=PMID:21127069, GO:0060732=PMID:15641770, GO:0048148=GO_REF:0000019, GO:0005634=PMID:12406186, GO:0030426=PMID:12958153, GO:0055074=PMID:12239163, GO:0005829=PMID:8248242, GO:0005640=GO_REF:0000019, GO:0042416=PMID:21320589, GO:0042393=PMID:16959795, GO:0040012=GO_REF:0000019, GO:0051622=PMID:17156375, GO:0033138=GO_REF:0000024, GO:0001963=GO_REF:0000019, GO:0006631=GO_REF:0000019, GO:0043205=PMID:18346205, GO:0043206=PMID:21320589, GO:0043154=PMID:10818098, GO:0001774=GO_REF:0000019, GO:0043014=PMID:11698390, GO:0016234=PMID:20039155, GO:0042493=GO_REF:0000019, GO:0048156=PMID:21127069, GO:0005576=Reactome:REACT_75905, GO:0044344=GO_REF:0000019, GO:0005840=GO_REF:0000019, GO:0008017=GO_REF:0000019, GO:0043030=GO_REF:0000019, GO:0032410=PMID:16882008, GO:0010040=PMID:11850416, GO:0060291=GO_REF:0000019, GO:0042802=PMID:18614564, GO:0045920=PMID:12239163, GO:0051583=PMID:21320589, GO:0043524=GO_REF:0000019, GO:0051585=PMID:12958153, GO:0048169=GO_REF:0000019, GO:0032026=PMID:11850416, GO:0032496=PMID:12406186, GO:0005856=GO_REF:0000019, GO:0005938=PMID:19157893, GO:0043027=PMID:10818098, GO:0007568=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0060079=GO_REF:0000019, GO:0048487=GO_REF:0000019, GO:0048488=GO_REF:0000024, GO:0045502=PMID:16176937, GO:0060961=PMID:19146388, GO:0050808=GO_REF:0000019, GO:0030544=PMID:18975920, GO:0019894=PMID:16176937, GO:0001956=GO_REF:0000019, GO:0055114=PMID:21320589, GO:0005886=PMID:12958153, GO:0035067=PMID:16959795, GO:0050812=GO_REF:0000019, GO:0015629=PMID:17408955, GO:0014059=PMID:21320589, GO:0045807=PMID:18980610, GO:0005739=GO_REF:0000019, GO:0005737=PMID:12406186, GO:0005543=GO_REF:0000019, GO:0070495=PMID:12239163, GO:0043195=GO_REF:0000019, GO:0001921=PMID:18980610, GO:0031092=PMID:12239163, GO:0010642=PMID:12239163, GO:0034341=PMID:19157893, GO:0051281=PMID:15641770, GO:0030659=GO_REF:0000019, GO:0070555=PMID:12406186, GO:0031115=PMID:21127069, GO:0043066=PMID:10818098, GO:0006919=PMID:21050448, GO:0014048=GO_REF:0000019, GO:0008198=PMID:11850416, GO:0008021=GO_REF:0000019, GO:0047485=GO_REF:0000019, GO:0001933=GO_REF:0000019, GO:0034599=GO_REF:0000019} P37840 Alpha-synuclein protein 20080926 {GO:0051219=IDA, GO:0005515=IPI, GO:0030054=IEA, GO:0050544=IEA, GO:0031623=IDA, GO:0043274=IEA, GO:0045963=IEA, GO:0005791=IEA, GO:0006638=IEA, GO:0005504=IDA, GO:0005794=IEA, GO:0000287=IDA, GO:0005507=IDA, GO:0005509=IDA, GO:0010517=IDA, GO:0032769=IDA, GO:0071872=TAS, GO:0042775=IEA, GO:0051612=IDA, GO:0007006=IEA, GO:0008270=IDA, GO:0006644=IEA, GO:0071280=IDA, GO:0008344=IEA, GO:0030424=IDA, GO:0048471=IDA, GO:0071902=IDA, GO:0060732=IDA, GO:0048148=IEA, GO:0005634=IDA, GO:0030426=IDA, GO:0055074=IDA, GO:0005829=IDA, GO:0005640=IEA, GO:0042416=TAS, GO:0042393=IDA, GO:0040012=IEA, GO:0051622=IDA, GO:0033138=ISS, GO:0001963=IEA, GO:0006631=IEA, GO:0043205=IDA, GO:0043206=TAS, GO:0043154=IMP, GO:0001774=IEA, GO:0043014=IPI, GO:0016234=IDA, GO:0042493=IEA, GO:0048156=IDA, GO:0005576=TAS, GO:0044344=IEA, GO:0005840=IEA, GO:0008017=IEA, GO:0043030=IEA, GO:0032410=IDA, GO:0010040=IDA, GO:0060291=IEA, GO:0042802=IPI, GO:0045920=IMP, GO:0051583=TAS, GO:0043524=IEA, GO:0051585=IDA, GO:0048169=IEA, GO:0032026=IDA, GO:0032496=IDA, GO:0005856=IEA, GO:0005938=IDA, GO:0043027=IDA, GO:0007568=IEA, GO:0019904=IEA, GO:0060079=IEA, GO:0048487=IEA, GO:0048488=ISS, GO:0045502=IPI, GO:0060961=IDA, GO:0050808=IEA, GO:0030544=IPI, GO:0019894=IPI, GO:0001956=IEA, GO:0055114=IDA, GO:0005886=IDA, GO:0035067=IDA, GO:0050812=IEA, GO:0015629=IDA, GO:0014059=TAS, GO:0045807=IDA, GO:0005739=IEA, GO:0005737=IDA, GO:0005543=IEA, GO:0070495=IDA, GO:0043195=IEA, GO:0001921=IDA, GO:0031092=IDA, GO:0010642=IDA, GO:0034341=IDA, GO:0051281=IDA, GO:0030659=IEA, GO:0070555=IDA, GO:0031115=IDA, GO:0043066=IMP, GO:0006919=IDA, GO:0014048=IEA, GO:0008198=IDA, GO:0008021=IEA, GO:0047485=IEA, GO:0001933=IEA, GO:0034599=IEA} activation of cysteine-type endopeptidase activity involved in apoptotic process, adult locomotory behavior, aging, behavioral response to cocaine, calcium ion homeostasis, cellular response to copper ion, cellular response to epinephrine stimulus, cellular response to fibroblast growth factor stimulus, cellular response to oxidative stress, dopamine biosynthetic process, dopamine uptake involved in synaptic transmission, extracellular fibril organization, fatty acid metabolic process, long-term synaptic potentiation, microglial cell activation, mitochondrial ATP synthesis coupled electron transport, mitochondrial membrane organization, negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of dopamine metabolic process, negative regulation of dopamine uptake involved in synaptic transmission, negative regulation of exocytosis, negative regulation of histone acetylation, negative regulation of microtubule polymerization, negative regulation of monooxygenase activity, negative regulation of neuron apoptotic process, negative regulation of norepinephrine uptake, negative regulation of platelet-derived growth factor receptor signaling pathway, negative regulation of protein phosphorylation, negative regulation of serotonin uptake, negative regulation of thrombin receptor signaling pathway, negative regulation of transporter activity, neutral lipid metabolic process, oxidation-reduction process, phospholipid metabolic process, positive regulation of endocytosis, positive regulation of inositol phosphate biosynthetic process, positive regulation of neurotransmitter secretion, positive regulation of peptidyl-serine phosphorylation, positive regulation of protein serine/threonine kinase activity, positive regulation of receptor recycling, positive regulation of release of sequestered calcium ion into cytosol, receptor internalization, regulation of acyl-CoA biosynthetic process, regulation of dopamine secretion, regulation of excitatory postsynaptic membrane potential, regulation of glutamate secretion, regulation of locomotion, regulation of long-term neuronal synaptic plasticity, regulation of macrophage activation, regulation of phospholipase activity, response to drug, response to interferon-gamma, response to interleukin-1, response to iron(II) ion, response to lipopolysaccharide, response to magnesium ion, synapse organization, synaptic transmission, dopaminergic, synaptic vesicle endocytosis Golgi apparatus, actin cytoskeleton, axon, cell cortex, cell junction, cytoplasm, cytoplasmic vesicle membrane, cytoskeleton, cytosol, extracellular region, fibril, growth cone, inclusion body, mitochondrion, nuclear outer membrane, nucleus, perinuclear region of cytoplasm, plasma membrane, platelet alpha granule membrane, ribosome, rough endoplasmic reticulum, synaptic vesicle, terminal bouton Hsp70 protein binding, alpha-tubulin binding, arachidonic acid binding, beta-tubulin binding, calcium ion binding, copper ion binding, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, dynein binding, fatty acid binding, ferrous iron binding, histone binding, identical protein binding, kinesin binding, magnesium ion binding, microtubule binding, phospholipase D inhibitor activity, phospholipase binding, phospholipid binding, phosphoprotein binding, protein N-terminus binding, protein binding, protein domain specific binding, tau protein binding, zinc ion binding Human SNCAIP HPA UniProtKB {GO:0090083=PMID:15603737, GO:0005515=PMID:11590439, GO:0042734=PMID:11956199, GO:0008219=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0042417=PMID:14506261, GO:0043025=PMID:11956199, GO:0005730=GO_REF:0000052, GO:0046928=PMID:14506261, GO:0005634=GO_REF:0000052, GO:0031625=PMID:15728840} Q9Y6H5 Synphilin-1 protein 20080205 {GO:0090083=IDA, GO:0005515=IPI, GO:0042734=NAS, GO:0008219=IEA, GO:0005737=IDA, GO:0042417=IDA, GO:0043025=NAS, GO:0005730=IDA, GO:0046928=IDA, GO:0005634=IDA, GO:0031625=IPI} cell death, dopamine metabolic process, regulation of inclusion body assembly, regulation of neurotransmitter secretion cytoplasm, neuronal cell body, nucleolus, nucleus, presynaptic membrane protein binding, ubiquitin protein ligase binding Human SNCB HPA UniProtKB {GO:0004859=PMID:9806846, GO:0005794=GO_REF:0000052, GO:0043014=GO_REF:0000019, GO:0005509=PMID:11312271, GO:0005730=GO_REF:0000052, GO:0048487=GO_REF:0000019, GO:0007268=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0030426=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0043524=GO_REF:0000019, GO:0042417=GO_REF:0000019, GO:0050808=GO_REF:0000019, GO:0043195=GO_REF:0000019, GO:0043025=GO_REF:0000019} Q16143 Beta-synuclein protein 20110516 {GO:0004859=TAS, GO:0005794=IDA, GO:0043014=IEA, GO:0005509=IDA, GO:0005730=IDA, GO:0048487=IEA, GO:0007268=IEA, GO:0005634=IDA, GO:0030426=IEA, GO:0005739=IEA, GO:0005737=IDA, GO:0043524=IEA, GO:0042417=IEA, GO:0050808=IEA, GO:0043195=IEA, GO:0043025=IEA} dopamine metabolic process, negative regulation of neuron apoptotic process, synapse organization, synaptic transmission Golgi apparatus, cytoplasm, growth cone, mitochondrion, neuronal cell body, nucleolus, nucleus, terminal bouton alpha-tubulin binding, beta-tubulin binding, calcium ion binding, phospholipase inhibitor activity Human SNCG UniProtKB UniProtKB {GO:0071464=GO_REF:0000019, GO:0008344=GO_REF:0000019, GO:0048471=GO_REF:0000039, GO:0005815=GO_REF:0000039, GO:0005886=GO_REF:0000019, GO:0043014=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0005819=GO_REF:0000039, GO:0048487=GO_REF:0000019, GO:0046928=GO_REF:0000019, GO:0007268=GO_REF:0000019, GO:0042220=GO_REF:0000019, GO:0014059=GO_REF:0000019, GO:0050808=GO_REF:0000019, GO:0002118=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0043679=GO_REF:0000019} O76070 Gamma-synuclein protein 20130413 {GO:0071464=IEA, GO:0008344=IEA, GO:0048471=IEA, GO:0005815=IEA, GO:0005886=IEA, GO:0043014=IEA, GO:0042493=IEA, GO:0005819=IEA, GO:0048487=IEA, GO:0046928=IEA, GO:0007268=IEA, GO:0042220=IEA, GO:0014059=IEA, GO:0050808=IEA, GO:0002118=IEA, GO:0043025=IEA, GO:0043679=IEA} adult locomotory behavior, aggressive behavior, cellular response to hydrostatic pressure, regulation of dopamine secretion, regulation of neurotransmitter secretion, response to cocaine, response to drug, synapse organization, synaptic transmission axon terminus, microtubule organizing center, neuronal cell body, perinuclear region of cytoplasm, plasma membrane, spindle alpha-tubulin binding, beta-tubulin binding Human UniProtKB-SubCell:SL-0198 SND1 HPA UniProtKB {GO:0003712=PMID:7651391, GO:0042470=GO_REF:0000039, GO:0006355=GO_REF:0000037, GO:0016788=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0031047=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0016442=GO_REF:0000002, GO:0005739=GO_REF:0000019, GO:0004518=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0019048=GO_REF:0000037} Q7KZF4 Staphylococcal nuclease domain-containing protein 1 protein 20080205 {GO:0003712=TAS, GO:0042470=IEA, GO:0006355=IEA, GO:0016788=IEA, GO:0005634=IEA, GO:0031047=IEA, GO:0003676=IEA, GO:0006351=IEA, GO:0016442=IEA, GO:0005739=IEA, GO:0004518=IEA, GO:0005737=IDA, GO:0019048=IEA} gene silencing by RNA, regulation of transcription, DNA-dependent, transcription, DNA-dependent, virus-host interaction RNA-induced silencing complex, cytoplasm, melanosome, mitochondrion, nucleus hydrolase activity, acting on ester bonds, nuclease activity, nucleic acid binding, transcription cofactor activity Human SNED1 UniProtKB UniProtKB {GO:0007160=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0005576=GO_REF:0000039} Q8TER0 Sushi, nidogen and EGF-like domain-containing protein 1 protein 20130413 {GO:0007160=IEA, GO:0005509=IEA, GO:0005576=IEA} cell-matrix adhesion extracellular region calcium ion binding Human UniProtKB-SubCell:SL-0243 SNF8 Reactome UniProtKB {GO:0005667=PMID:10419521, GO:0006357=PMID:10419521, GO:0016197=Reactome:REACT_27258, GO:0031902=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0016044=Reactome:REACT_11123, GO:0006351=GO_REF:0000037, GO:0005829=Reactome:REACT_27319, GO:0008134=PMID:10419521} Q96H20 Vacuolar-sorting protein SNF8 protein 20100729 {GO:0005667=IDA, GO:0006357=IDA, GO:0016197=TAS, GO:0031902=IEA, GO:0015031=IEA, GO:0016044=TAS, GO:0006351=IEA, GO:0005829=TAS, GO:0008134=IDA} cellular membrane organization, endosomal transport, protein transport, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cytosol, late endosome membrane, transcription factor complex transcription factor binding Human SNIP1 HPA UniProtKB {GO:0005515=PMID:17157259, GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000019, GO:0035196=PMID:18632581, GO:0005730=GO_REF:0000052, GO:0007249=GO_REF:0000019, GO:0005634=GO_REF:0000052} Q8TAD8 Smad nuclear-interacting protein 1 protein 20110516 {GO:0005515=IPI, GO:0005737=IDA, GO:0006355=IEA, GO:0035196=IMP, GO:0005730=IDA, GO:0007249=IEA, GO:0005634=IDA} I-kappaB kinase/NF-kappaB cascade, production of miRNAs involved in gene silencing by miRNA, regulation of transcription, DNA-dependent cytoplasm, nucleolus, nucleus protein binding Human SNPH UniProtKB UniProtKB {GO:0005881=PMID:23264731, GO:0043005=GO_REF:0000039, GO:0016081=PMID:10707983, GO:0030054=GO_REF:0000037, GO:0031966=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0007269=PMID:10707983, GO:0042734=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0030182=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0017075=PMID:10707983} O15079 Syntaphilin protein 20130311 {GO:0005881=IDA, GO:0043005=IEA, GO:0016081=NAS, GO:0030054=IEA, GO:0031966=IEA, GO:0005886=IEA, GO:0005575=ND, GO:0007269=NAS, GO:0042734=IEA, GO:0007420=IEA, GO:0030182=IEA, GO:0043025=IEA, GO:0016021=IEA, GO:0017075=NAS} brain development, neuron differentiation, neurotransmitter secretion, synaptic vesicle docking involved in exocytosis cell junction, cellular_component, cytoplasmic microtubule, integral to membrane, mitochondrial membrane, neuron projection, neuronal cell body, plasma membrane, presynaptic membrane syntaxin-1 binding Human SNRK UniProtKB UniProtKB {GO:0000287=PMID:12234663, GO:0004674=PMID:12234663, GO:0030099=PMID:12234663, GO:0006468=PMID:12234663, GO:0005634=GO_REF:0000024, GO:0005524=PMID:12234663} Q9NRH2 SNF-related serine/threonine-protein kinase protein 20060209 {GO:0000287=IDA, GO:0004674=IDA, GO:0030099=TAS, GO:0006468=IDA, GO:0005634=ISS, GO:0005524=IDA} myeloid cell differentiation, protein phosphorylation nucleus ATP binding, magnesium ion binding, protein serine/threonine kinase activity Human UniProtKB:Q63553 SNRNP200 HPA UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0008026=PMID:9539711, GO:0005515=PMID:18951082, GO:0010467=Reactome:REACT_71, GO:0004386=GO_REF:0000038, GO:0005730=GO_REF:0000052, GO:0000354=PMID:9539711, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0071013=PMID:11991638, GO:0005524=GO_REF:0000037, GO:0004004=PMID:23045696, GO:0000398=Reactome:REACT_1753, GO:0030529=GO_REF:0000038, GO:0005654=Reactome:REACT_2241, GO:0005681=PMID:8670905, GO:0005682=PMID:9539711} O75643 U5 small nuclear ribonucleoprotein 200 kDa helicase protein 20101115 {GO:0008380=TAS, GO:0008026=IDA, GO:0005515=IPI, GO:0010467=TAS, GO:0004386=IEA, GO:0005730=IDA, GO:0000354=IC, GO:0005634=IDA, GO:0003676=IEA, GO:0071013=IDA, GO:0005524=IEA, GO:0004004=IDA, GO:0000398=TAS, GO:0030529=IEA, GO:0005654=TAS, GO:0005681=IDA, GO:0005682=IDA} RNA splicing, cis assembly of pre-catalytic spliceosome, gene expression, mRNA splicing, via spliceosome U5 snRNP, catalytic step 2 spliceosome, nucleolus, nucleoplasm, nucleus, ribonucleoprotein complex, spliceosomal complex ATP binding, ATP-dependent RNA helicase activity, ATP-dependent helicase activity, helicase activity, nucleic acid binding, protein binding NOT Human SNRNP25 HGNC UniProtKB {GO:0008380=PMID:15146077, GO:0006397=GO_REF:0000037, GO:0005634=PMID:18559850, GO:0005689=PMID:15146077} Q9BV90 U11/U12 small nuclear ribonucleoprotein 25 kDa protein protein 20060131 {GO:0008380=IC, GO:0006397=IEA, GO:0005634=IDA, GO:0005689=IDA} RNA splicing, mRNA processing U12-type spliceosomal complex, nucleus Human GO:0005689 SNRNP27 UniProtKB UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0008150=GO_REF:0000015, GO:0005634=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0003676=PMID:7931148} Q8WVK2 U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein protein 20061106 {GO:0008380=IEA, GO:0006397=IEA, GO:0008150=ND, GO:0005634=IEA, GO:0005575=ND, GO:0003676=NAS} RNA splicing, biological_process, mRNA processing cellular_component, nucleus nucleic acid binding Human SNRNP35 HGNC UniProtKB {GO:0008380=PMID:15146077, GO:0006397=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005634=PMID:18559850, GO:0005689=PMID:15146077} Q16560 U11/U12 small nuclear ribonucleoprotein 35 kDa protein protein 20060131 {GO:0008380=IC, GO:0006397=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0005634=IDA, GO:0005689=IDA} RNA splicing, mRNA processing U12-type spliceosomal complex, nucleus RNA binding, nucleotide binding Human GO:0005689 SNRNP40 HPA UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0006396=PMID:9774689, GO:0005737=GO_REF:0000052, GO:0000398=Reactome:REACT_1753, GO:0000375=PMID:9774689, GO:0005730=GO_REF:0000052, GO:0005654=Reactome:REACT_2241, GO:0005732=PMID:9774689, GO:0005634=GO_REF:0000052, GO:0005682=PMID:9774689, GO:0071013=PMID:11991638} Q96DI7 U5 small nuclear ribonucleoprotein 40 kDa protein protein 20100326 {GO:0008380=TAS, GO:0010467=TAS, GO:0006396=TAS, GO:0005737=IDA, GO:0000398=TAS, GO:0000375=TAS, GO:0005730=IDA, GO:0005654=TAS, GO:0005732=NAS, GO:0005634=IDA, GO:0005682=TAS, GO:0071013=IDA} RNA processing, RNA splicing, RNA splicing, via transesterification reactions, gene expression, mRNA splicing, via spliceosome U5 snRNP, catalytic step 2 spliceosome, cytoplasm, nucleolus, nucleoplasm, nucleus, small nucleolar ribonucleoprotein complex Human SNRNP48 HPA UniProtKB {GO:0008380=PMID:15146077, GO:0006397=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005689=PMID:15146077, GO:0046872=GO_REF:0000037} Q6IEG0 U11/U12 small nuclear ribonucleoprotein 48 kDa protein protein 20101115 {GO:0008380=IC, GO:0006397=IEA, GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0005689=IDA, GO:0046872=IEA} RNA splicing, mRNA processing U12-type spliceosomal complex, cytoplasm, nucleolus, nucleus metal ion binding Human SNRNP70 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0006397=PMID:3028775, GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0003723=PMID:2467746, GO:0005634=PMID:18559850, GO:0003676=GO_REF:0000002, GO:0000166=GO_REF:0000002, GO:0016607=GO_REF:0000039, GO:0000398=Reactome:REACT_467, GO:0043484=PMID:2467746, GO:0005681=PMID:9731529, GO:0005654=Reactome:REACT_788} P08621 U1 small nuclear ribonucleoprotein 70 kDa protein 20130415 {GO:0005515=IPI, GO:0006397=TAS, GO:0008380=TAS, GO:0010467=TAS, GO:0003723=IMP, GO:0005634=IDA, GO:0003676=IEA, GO:0000166=IEA, GO:0016607=IEA, GO:0000398=TAS, GO:0043484=IMP, GO:0005681=IDA, GO:0005654=TAS} RNA splicing, gene expression, mRNA processing, mRNA splicing, via spliceosome, regulation of RNA splicing nuclear speck, nucleoplasm, nucleus, spliceosomal complex RNA binding, nucleic acid binding, nucleotide binding, protein binding Human UniProtKB:P49760 SNRPA IntAct UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:9848648, GO:0010467=Reactome:REACT_71, GO:0000166=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0003723=PMID:19561594, GO:0017069=GO_REF:0000002, GO:0005654=Reactome:REACT_788, GO:0005681=PMID:9731529} P09012 U1 small nuclear ribonucleoprotein A protein 20130415 {GO:0008380=TAS, GO:0005515=IPI, GO:0010467=TAS, GO:0000166=IEA, GO:0000398=TAS, GO:0003723=IDA, GO:0017069=IEA, GO:0005654=TAS, GO:0005681=IDA} RNA splicing, gene expression, mRNA splicing, via spliceosome nucleoplasm, spliceosomal complex RNA binding, nucleotide binding, protein binding, snRNA binding Human UniProtKB:P23246 SNRPA1 Reactome UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:9716128, GO:0010467=Reactome:REACT_71, GO:0000398=Reactome:REACT_467, GO:0003723=GO_REF:0000037, GO:0030529=GO_REF:0000038, GO:0030532=PMID:2928112, GO:0005654=Reactome:REACT_1935, GO:0005681=PMID:9731529, GO:0071013=PMID:11991638, GO:0003676=GO_REF:0000038, GO:0005686=PMID:2928112} P09661 U2 small nuclear ribonucleoprotein A' protein 20130213 {GO:0008380=TAS, GO:0005515=IPI, GO:0010467=TAS, GO:0000398=TAS, GO:0003723=IEA, GO:0030529=IEA, GO:0030532=TAS, GO:0005654=TAS, GO:0005681=IDA, GO:0071013=IDA, GO:0003676=IEA, GO:0005686=TAS} RNA splicing, gene expression, mRNA splicing, via spliceosome U2 snRNP, catalytic step 2 spliceosome, nucleoplasm, ribonucleoprotein complex, small nuclear ribonucleoprotein complex, spliceosomal complex RNA binding, nucleic acid binding, protein binding Human SNRPB Reactome UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:18951082, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0016070=Reactome:REACT_21257, GO:0008334=Reactome:REACT_1364, GO:0006366=Reactome:REACT_1366, GO:0031124=Reactome:REACT_1768, GO:0034660=Reactome:REACT_11052, GO:0071013=PMID:11991638, GO:0000387=Reactome:REACT_11066, GO:0005829=Reactome:REACT_10041, GO:0000398=Reactome:REACT_1753, GO:0005683=PMID:11574479, GO:0030532=PMID:2531083, GO:0005681=PMID:2531083, GO:0005654=Reactome:REACT_10010, GO:0071204=GO_REF:0000019, GO:0005689=PMID:15146077, GO:0071208=GO_REF:0000019} P14678 Small nuclear ribonucleoprotein-associated proteins B and B' protein 20130213 {GO:0008380=TAS, GO:0005515=IPI, GO:0010467=TAS, GO:0006369=TAS, GO:0016070=TAS, GO:0008334=TAS, GO:0006366=TAS, GO:0031124=TAS, GO:0034660=TAS, GO:0071013=IDA, GO:0000387=TAS, GO:0005829=TAS, GO:0000398=TAS, GO:0005683=IDA, GO:0030532=TAS, GO:0005681=TAS, GO:0005654=TAS, GO:0071204=IEA, GO:0005689=IDA, GO:0071208=IEA} RNA metabolic process, RNA splicing, gene expression, histone mRNA metabolic process, mRNA 3'-end processing, mRNA splicing, via spliceosome, ncRNA metabolic process, spliceosomal snRNP assembly, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter U12-type spliceosomal complex, U7 snRNP, catalytic step 2 spliceosome, cytosol, histone pre-mRNA 3'end processing complex, nucleoplasm, small nuclear ribonucleoprotein complex, spliceosomal complex histone pre-mRNA DCP binding, protein binding Human SNRPB2 Reactome UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:9716128, GO:0006397=PMID:2951739, GO:0010467=Reactome:REACT_71, GO:0000166=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0017069=GO_REF:0000002, GO:0005654=Reactome:REACT_1935, GO:0005681=PMID:9731529, GO:0071013=PMID:11991638, GO:0005686=PMID:2951739} P08579 U2 small nuclear ribonucleoprotein B'' protein 20130213 {GO:0008380=TAS, GO:0005515=IPI, GO:0006397=TAS, GO:0010467=TAS, GO:0000166=IEA, GO:0000398=TAS, GO:0017069=IEA, GO:0005654=TAS, GO:0005681=IDA, GO:0071013=IDA, GO:0005686=TAS} RNA splicing, gene expression, mRNA processing, mRNA splicing, via spliceosome U2 snRNP, catalytic step 2 spliceosome, nucleoplasm, spliceosomal complex nucleotide binding, protein binding, snRNA binding Human SNRPC InterPro UniProtKB {GO:0005515=PMID:8076607, GO:0030619=PMID:1826349, GO:0003727=PMID:8798632, GO:0015030=PMID:10068039, GO:0000398=PMID:8972845, GO:0008270=PMID:15312772, GO:0000387=GO_REF:0000002, GO:0042803=PMID:8532530, GO:0005685=GO_REF:0000002} Q5TAL2 U1 small nuclear ribonucleoprotein C protein 20130413 {GO:0005515=IPI, GO:0030619=IDA, GO:0003727=IDA, GO:0015030=IDA, GO:0000398=IDA, GO:0008270=IDA, GO:0000387=IEA, GO:0042803=IPI, GO:0005685=IEA} mRNA splicing, via spliceosome, spliceosomal snRNP assembly Cajal body, U1 snRNP U1 snRNA binding, protein binding, protein homodimerization activity, single-stranded RNA binding, zinc ion binding Human InterPro:IPR017340 SNRPD1 IntAct UniProtKB {GO:0005515=PMID:18984161, GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0000245=PMID:7527560, GO:0016070=Reactome:REACT_21257, GO:0003723=PMID:3260384, GO:0005634=PMID:3260384, GO:0034660=Reactome:REACT_11052, GO:0071013=PMID:11991638, GO:0000387=Reactome:REACT_11066, GO:0005829=Reactome:REACT_10041, GO:0005737=GO_REF:0000019, GO:0000398=Reactome:REACT_1753, GO:0030532=PMID:7527560, GO:0005654=Reactome:REACT_10010, GO:0005689=PMID:15146077} P62314 Small nuclear ribonucleoprotein Sm D1 protein 20130415 {GO:0005515=IPI, GO:0008380=TAS, GO:0010467=TAS, GO:0000245=TAS, GO:0016070=TAS, GO:0003723=TAS, GO:0005634=TAS, GO:0034660=TAS, GO:0071013=IDA, GO:0000387=TAS, GO:0005829=TAS, GO:0005737=IEA, GO:0000398=TAS, GO:0030532=TAS, GO:0005654=TAS, GO:0005689=IDA} RNA metabolic process, RNA splicing, gene expression, mRNA splicing, via spliceosome, ncRNA metabolic process, spliceosomal complex assembly, spliceosomal snRNP assembly U12-type spliceosomal complex, catalytic step 2 spliceosome, cytoplasm, cytosol, nucleoplasm, nucleus, small nuclear ribonucleoprotein complex RNA binding, protein binding Human UniProtKB:P54105 SNRPD2 Reactome UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:11748230, GO:0000245=PMID:7527560, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0034660=Reactome:REACT_11052, GO:0071013=PMID:11991638, GO:0000387=Reactome:REACT_11066, GO:0005829=Reactome:REACT_10041, GO:0000398=Reactome:REACT_1753, GO:0030532=GO_REF:0000002, GO:0005681=PMID:1701240, GO:0005654=Reactome:REACT_10010, GO:0005689=PMID:15146077} P62316 Small nuclear ribonucleoprotein Sm D2 protein 20130213 {GO:0008380=TAS, GO:0005515=IPI, GO:0000245=TAS, GO:0010467=TAS, GO:0016070=TAS, GO:0034660=TAS, GO:0071013=IDA, GO:0000387=TAS, GO:0005829=TAS, GO:0000398=TAS, GO:0030532=IEA, GO:0005681=TAS, GO:0005654=TAS, GO:0005689=IDA} RNA metabolic process, RNA splicing, gene expression, mRNA splicing, via spliceosome, ncRNA metabolic process, spliceosomal complex assembly, spliceosomal snRNP assembly U12-type spliceosomal complex, catalytic step 2 spliceosome, cytosol, nucleoplasm, small nuclear ribonucleoprotein complex, spliceosomal complex protein binding Human SNRPD3 IntAct UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:21988832, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0016070=Reactome:REACT_21257, GO:0008334=Reactome:REACT_1364, GO:0006366=Reactome:REACT_1366, GO:0031124=Reactome:REACT_1768, GO:0034660=Reactome:REACT_11052, GO:0003676=GO_REF:0000038, GO:0071013=PMID:11991638, GO:0000387=Reactome:REACT_11066, GO:0005829=Reactome:REACT_10041, GO:0000398=Reactome:REACT_1753, GO:0030529=GO_REF:0000038, GO:0005683=PMID:11574479, GO:0030532=PMID:1701240, GO:0005681=PMID:7527560, GO:0005654=Reactome:REACT_10010, GO:0019899=PMID:17709427, GO:0005689=PMID:15146077, GO:0071208=GO_REF:0000024} P62318 Small nuclear ribonucleoprotein Sm D3 protein 20130415 {GO:0008380=TAS, GO:0005515=IPI, GO:0010467=TAS, GO:0006369=TAS, GO:0016070=TAS, GO:0008334=TAS, GO:0006366=TAS, GO:0031124=TAS, GO:0034660=TAS, GO:0003676=IEA, GO:0071013=IDA, GO:0000387=TAS, GO:0005829=TAS, GO:0000398=TAS, GO:0030529=IEA, GO:0005683=IDA, GO:0030532=TAS, GO:0005681=TAS, GO:0005654=TAS, GO:0019899=IPI, GO:0005689=IDA, GO:0071208=ISS} RNA metabolic process, RNA splicing, gene expression, histone mRNA metabolic process, mRNA 3'-end processing, mRNA splicing, via spliceosome, ncRNA metabolic process, spliceosomal snRNP assembly, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter U12-type spliceosomal complex, U7 snRNP, catalytic step 2 spliceosome, cytosol, nucleoplasm, ribonucleoprotein complex, small nuclear ribonucleoprotein complex, spliceosomal complex enzyme binding, histone pre-mRNA DCP binding, nucleic acid binding, protein binding Human UniProtKB:P54105 SNRPE IntAct UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:11714716, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0000245=PMID:2974536, GO:0016070=Reactome:REACT_21257, GO:0008334=Reactome:REACT_1364, GO:0006366=Reactome:REACT_1366, GO:0003723=GO_REF:0000037, GO:0031124=Reactome:REACT_1768, GO:0034660=Reactome:REACT_11052, GO:0071013=PMID:11991638, GO:0000387=Reactome:REACT_11066, GO:0005829=Reactome:REACT_10041, GO:0000398=Reactome:REACT_1753, GO:0030532=PMID:2974536, GO:0005683=PMID:11574479, GO:0005681=PMID:2974536, GO:0005654=Reactome:REACT_10010, GO:0005689=PMID:15146077} P62304 Small nuclear ribonucleoprotein E protein 20130415 {GO:0008380=TAS, GO:0005515=IPI, GO:0010467=TAS, GO:0006369=TAS, GO:0000245=NAS, GO:0016070=TAS, GO:0008334=TAS, GO:0006366=TAS, GO:0003723=IEA, GO:0031124=TAS, GO:0034660=TAS, GO:0071013=IDA, GO:0000387=TAS, GO:0005829=TAS, GO:0000398=TAS, GO:0030532=NAS, GO:0005683=IDA, GO:0005681=NAS, GO:0005654=TAS, GO:0005689=IDA} RNA metabolic process, RNA splicing, gene expression, histone mRNA metabolic process, mRNA 3'-end processing, mRNA splicing, via spliceosome, ncRNA metabolic process, spliceosomal complex assembly, spliceosomal snRNP assembly, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter U12-type spliceosomal complex, U7 snRNP, catalytic step 2 spliceosome, cytosol, nucleoplasm, small nuclear ribonucleoprotein complex, spliceosomal complex RNA binding, protein binding Human UniProtKB:Q8TEQ6 SNRPF Reactome UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0016070=Reactome:REACT_21257, GO:0008334=Reactome:REACT_1364, GO:0006366=Reactome:REACT_1366, GO:0003723=PMID:7744013, GO:0031124=Reactome:REACT_1768, GO:0034660=Reactome:REACT_11052, GO:0071013=PMID:11991638, GO:0000387=Reactome:REACT_11066, GO:0005829=Reactome:REACT_10041, GO:0000398=Reactome:REACT_1753, GO:0030532=PMID:11991638, GO:0005683=PMID:11574479, GO:0005681=PMID:7744013, GO:0005654=Reactome:REACT_10010, GO:0005689=PMID:15146077} P62306 Small nuclear ribonucleoprotein F protein 20130213 {GO:0008380=TAS, GO:0010467=TAS, GO:0006369=TAS, GO:0016070=TAS, GO:0008334=TAS, GO:0006366=TAS, GO:0003723=IMP, GO:0031124=TAS, GO:0034660=TAS, GO:0071013=IDA, GO:0000387=TAS, GO:0005829=TAS, GO:0000398=TAS, GO:0030532=IDA, GO:0005683=IDA, GO:0005681=IDA, GO:0005654=TAS, GO:0005689=IDA} RNA metabolic process, RNA splicing, gene expression, histone mRNA metabolic process, mRNA 3'-end processing, mRNA splicing, via spliceosome, ncRNA metabolic process, spliceosomal snRNP assembly, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter U12-type spliceosomal complex, U7 snRNP, catalytic step 2 spliceosome, cytosol, nucleoplasm, small nuclear ribonucleoprotein complex, spliceosomal complex RNA binding Human SNRPG IntAct UniProtKB {GO:0005515=PMID:14603251, GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0000245=PMID:7744013, GO:0006369=Reactome:REACT_894, GO:0016070=Reactome:REACT_21257, GO:0008334=Reactome:REACT_1364, GO:0006366=Reactome:REACT_1366, GO:0003723=GO_REF:0000037, GO:0031124=Reactome:REACT_1768, GO:0034660=Reactome:REACT_11052, GO:0000387=Reactome:REACT_11066, GO:0071013=PMID:11991638, GO:0005829=Reactome:REACT_10041, GO:0000398=Reactome:REACT_1753, GO:0030532=PMID:7744013, GO:0005683=PMID:11574479, GO:0005681=PMID:7744013, GO:0005654=Reactome:REACT_10010, GO:0005689=PMID:15146077} P62308 Small nuclear ribonucleoprotein G protein 20130415 {GO:0005515=IPI, GO:0008380=TAS, GO:0010467=TAS, GO:0000245=NAS, GO:0006369=TAS, GO:0016070=TAS, GO:0008334=TAS, GO:0006366=TAS, GO:0003723=IEA, GO:0031124=TAS, GO:0034660=TAS, GO:0000387=TAS, GO:0071013=IDA, GO:0005829=TAS, GO:0000398=TAS, GO:0030532=NAS, GO:0005683=IDA, GO:0005681=TAS, GO:0005654=TAS, GO:0005689=IDA} RNA metabolic process, RNA splicing, gene expression, histone mRNA metabolic process, mRNA 3'-end processing, mRNA splicing, via spliceosome, ncRNA metabolic process, spliceosomal complex assembly, spliceosomal snRNP assembly, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter U12-type spliceosomal complex, U7 snRNP, catalytic step 2 spliceosome, cytosol, nucleoplasm, small nuclear ribonucleoprotein complex, spliceosomal complex RNA binding, protein binding Human UniProtKB:O75410-1 SNRPN IntAct UniProtKB {GO:0005515=PMID:14715275, GO:0008380=PMID:1533223, GO:0030529=GO_REF:0000038, GO:0003723=GO_REF:0000037, GO:0030532=PMID:7512861, GO:0005681=PMID:1533223, GO:0005634=GO_REF:0000040, GO:0009725=GO_REF:0000019, GO:0005685=GO_REF:0000019, GO:0005686=GO_REF:0000019} P63162 Small nuclear ribonucleoprotein-associated protein N protein 20130415 {GO:0005515=IPI, GO:0008380=TAS, GO:0030529=IEA, GO:0003723=IEA, GO:0030532=TAS, GO:0005681=TAS, GO:0005634=IEA, GO:0009725=IEA, GO:0005685=IEA, GO:0005686=IEA} RNA splicing, response to hormone stimulus U1 snRNP, U2 snRNP, nucleus, ribonucleoprotein complex, small nuclear ribonucleoprotein complex, spliceosomal complex RNA binding, protein binding Human UniProtKB:Q9VV74 SNTA1 IntAct UniProtKB {GO:0005515=PMID:16192269, GO:0005516=GO_REF:0000037, GO:0030054=GO_REF:0000039, GO:0003779=GO_REF:0000037, GO:0003117=GO_REF:0000019, GO:0042383=GO_REF:0000039, GO:0005622=PMID:17628813, GO:0005737=GO_REF:0000037, GO:0005543=GO_REF:0000002, GO:0006936=PMID:8576247, GO:0007528=GO_REF:0000019, GO:0045211=GO_REF:0000019, GO:0005856=GO_REF:0000039} Q13424 Alpha-1-syntrophin protein 20130415 {GO:0005515=IPI, GO:0005516=IEA, GO:0030054=IEA, GO:0003779=IEA, GO:0003117=IEA, GO:0042383=IEA, GO:0005622=IDA, GO:0005737=IEA, GO:0005543=IEA, GO:0006936=TAS, GO:0007528=IEA, GO:0045211=IEA, GO:0005856=IEA} muscle contraction, neuromuscular junction development, regulation of vasoconstriction by circulating norepinephrine cell junction, cytoplasm, cytoskeleton, intracellular, postsynaptic membrane, sarcolemma actin binding, calmodulin binding, phospholipid binding, protein binding Human UniProtKB:O95477 SNTB1 IntAct UniProtKB {GO:0005515=PMID:16192269, GO:0005516=GO_REF:0000037, GO:0030054=GO_REF:0000039, GO:0045202=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0030165=GO_REF:0000019, GO:0042383=GO_REF:0000039, GO:0043234=PMID:18468998, GO:0005737=GO_REF:0000037, GO:0005543=GO_REF:0000002, GO:0006936=PMID:8183929, GO:0016010=PMID:8119949, GO:0005856=GO_REF:0000039} Q13884 Beta-1-syntrophin protein 20130415 {GO:0005515=IPI, GO:0005516=IEA, GO:0030054=IEA, GO:0045202=IEA, GO:0003779=IEA, GO:0030165=IEA, GO:0042383=IEA, GO:0043234=IDA, GO:0005737=IEA, GO:0005543=IEA, GO:0006936=TAS, GO:0016010=TAS, GO:0005856=IEA} muscle contraction cell junction, cytoplasm, cytoskeleton, dystrophin-associated glycoprotein complex, protein complex, sarcolemma, synapse PDZ domain binding, actin binding, calmodulin binding, phospholipid binding, protein binding Human UniProtKB:O95477 SNTB2 MGI UniProtKB {GO:0005515=PMID:19786618, GO:0043234=PMID:18468998, GO:0005516=GO_REF:0000037, GO:0005737=PMID:19786618, GO:0030054=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0016010=PMID:8576247, GO:0016020=PMID:8576247, GO:0005874=GO_REF:0000037, GO:0045202=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0030658=GO_REF:0000039} Q13425 Beta-2-syntrophin protein 20120724 {GO:0005515=IPI, GO:0043234=IDA, GO:0005516=IEA, GO:0005737=IDA, GO:0030054=IEA, GO:0005543=IEA, GO:0016010=TAS, GO:0016020=TAS, GO:0005874=IEA, GO:0045202=IEA, GO:0003779=IEA, GO:0030658=IEA} cell junction, cytoplasm, dystrophin-associated glycoprotein complex, membrane, microtubule, protein complex, synapse, transport vesicle membrane actin binding, calmodulin binding, phospholipid binding, protein binding Human SNTG1 LIFEdb UniProtKB {GO:0005737=PMID:15485858, GO:0007154=PMID:10747910, GO:0005543=GO_REF:0000002, GO:0016013=PMID:10747910, GO:0032587=PMID:15485858, GO:0005634=GO_REF:0000039, GO:0003779=GO_REF:0000037, GO:0005856=GO_REF:0000054, GO:0008022=PMID:15485858} Q9NSN8 Gamma-1-syntrophin protein 20100607 {GO:0005737=IDA, GO:0007154=TAS, GO:0005543=IEA, GO:0016013=TAS, GO:0032587=IDA, GO:0005634=IEA, GO:0003779=IEA, GO:0005856=IDA, GO:0008022=IPI} cell communication cytoplasm, cytoskeleton, nucleus, ruffle membrane, syntrophin complex actin binding, phospholipid binding, protein C-terminus binding Human SNTG2 PINC UniProtKB {GO:0042383=GO_REF:0000039, GO:0005737=GO_REF:0000037, GO:0005543=GO_REF:0000002, GO:0016013=PMID:10747910, GO:0003779=GO_REF:0000037, GO:0007417=PMID:10747910, GO:0030165=PMID:17292328, GO:0005856=GO_REF:0000039} Q9NY99 Gamma-2-syntrophin protein 20030904 {GO:0042383=IEA, GO:0005737=IEA, GO:0005543=IEA, GO:0016013=TAS, GO:0003779=IEA, GO:0007417=TAS, GO:0030165=IPI, GO:0005856=IEA} central nervous system development cytoplasm, cytoskeleton, sarcolemma, syntrophin complex PDZ domain binding, actin binding, phospholipid binding Human SNUPN Reactome UniProtKB {GO:0000339=PMID:9670026, GO:0010467=Reactome:REACT_71, GO:0005737=GO_REF:0000002, GO:0016070=Reactome:REACT_21257, GO:0005643=PMID:9670026, GO:0008565=GO_REF:0000002, GO:0005634=GO_REF:0000002, GO:0034660=Reactome:REACT_11052, GO:0000387=Reactome:REACT_11066, GO:0006606=GO_REF:0000002, GO:0061015=GO_REF:0000002, GO:0005829=Reactome:REACT_10010} O95149 Snurportin-1 protein 20130213 {GO:0000339=TAS, GO:0010467=TAS, GO:0005737=IEA, GO:0016070=TAS, GO:0005643=TAS, GO:0008565=IEA, GO:0005634=IEA, GO:0034660=TAS, GO:0000387=TAS, GO:0006606=IEA, GO:0061015=IEA, GO:0005829=TAS} RNA metabolic process, gene expression, ncRNA metabolic process, protein import into nucleus, snRNA import into nucleus, spliceosomal snRNP assembly cytoplasm, cytosol, nuclear pore, nucleus RNA cap binding, protein transporter activity Human SNURF UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005634=PMID:10318933} Q9Y675 SNRPN upstream reading frame protein protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0005634=NAS} biological_process nucleus molecular_function Human SNW1 HPA UniProtKB {GO:0005515=PMID:21460037, GO:0048026=PMID:12840015, GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_14835, GO:0071300=PMID:19934264, GO:0005112=PMID:10713164, GO:0035257=PMID:19934264, GO:0005634=GO_REF:0000052, GO:0046332=PMID:11278756, GO:0071013=PMID:11991638, GO:0042974=PMID:11514567, GO:0016363=PMID:12840015, GO:0007219=Reactome:REACT_118859, GO:0050769=GO_REF:0000024, GO:0042809=PMID:12529369, GO:0045944=PMID:14985122, GO:0005681=PMID:15194481, GO:0000785=GO_REF:0000019, GO:0030511=PMID:11278756, GO:0008024=PMID:15905409, GO:0071146=PMID:11278756, GO:0006357=PMID:9632709, GO:0003714=PMID:14985122, GO:0003713=PMID:14985122, GO:0005730=GO_REF:0000052, GO:0000122=PMID:14985122, GO:0043923=PMID:19818711, GO:0070562=PMID:14985122, GO:0048384=PMID:19934264, GO:0042771=PMID:21460037, GO:0048385=PMID:14985122, GO:0051571=PMID:19818711, GO:0000398=PMID:11991638, GO:0019048=GO_REF:0000037, GO:0044428=PMID:9569025, GO:0005654=Reactome:REACT_160309, GO:0045892=PMID:15878163, GO:0070564=PMID:11514567} Q13573 SNW domain-containing protein 1 protein 20090616 {GO:0005515=IPI, GO:0048026=IMP, GO:0010467=TAS, GO:0006367=TAS, GO:0071300=IDA, GO:0005112=IPI, GO:0035257=IDA, GO:0005634=IDA, GO:0046332=IDA, GO:0071013=IDA, GO:0042974=IDA, GO:0016363=IDA, GO:0007219=TAS, GO:0050769=ISS, GO:0042809=IDA, GO:0045944=IDA, GO:0005681=IDA, GO:0000785=IEA, GO:0030511=IDA, GO:0008024=IDA, GO:0071146=IDA, GO:0006357=TAS, GO:0003714=IDA, GO:0003713=IDA, GO:0005730=IDA, GO:0000122=IDA, GO:0043923=IMP, GO:0070562=IDA, GO:0048384=IDA, GO:0042771=IMP, GO:0048385=IDA, GO:0051571=IMP, GO:0000398=IC, GO:0019048=IEA, GO:0044428=IDA, GO:0005654=TAS, GO:0045892=IDA, GO:0070564=IDA} Notch signaling pathway, cellular response to retinoic acid, gene expression, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, mRNA splicing, via spliceosome, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation by host of viral transcription, positive regulation of histone H3-K4 methylation, positive regulation of mRNA splicing, via spliceosome, positive regulation of neurogenesis, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transforming growth factor beta receptor signaling pathway, positive regulation of vitamin D receptor signaling pathway, regulation of retinoic acid receptor signaling pathway, regulation of transcription from RNA polymerase II promoter, regulation of vitamin D receptor signaling pathway, retinoic acid receptor signaling pathway, transcription initiation from RNA polymerase II promoter, virus-host interaction SMAD3-SMAD4 protein complex, catalytic step 2 spliceosome, chromatin, nuclear matrix, nuclear part, nucleolus, nucleoplasm, nucleus, positive transcription elongation factor complex b, spliceosomal complex Notch binding, SMAD binding, nuclear hormone receptor binding, protein binding, retinoic acid receptor binding, transcription coactivator activity, transcription corepressor activity, vitamin D receptor binding NOT Human SNX1 HPA UniProtKB {GO:0005515=PMID:11279102, GO:0045732=GO_REF:0000019, GO:0005794=GO_REF:0000039, GO:0006886=PMID:15498486, GO:0006897=PMID:9819414, GO:0043231=GO_REF:0000052, GO:0005829=GO_REF:0000019, GO:0005737=PMID:11279102, GO:0007154=GO_REF:0000002, GO:0016020=GO_REF:0000019, GO:0034498=PMID:15498486, GO:0031901=PMID:15498486, GO:0008565=GO_REF:0000002, GO:0016197=GO_REF:0000019, GO:0035091=PMID:15498486, GO:0010008=PMID:15673616, GO:0005768=GO_REF:0000019} Q13596 Sorting nexin-1 protein 20120912 {GO:0005515=IPI, GO:0045732=IEA, GO:0005794=IEA, GO:0006886=IMP, GO:0006897=TAS, GO:0043231=IDA, GO:0005829=IEA, GO:0005737=IDA, GO:0007154=IEA, GO:0016020=IEA, GO:0034498=IMP, GO:0031901=IDA, GO:0008565=IEA, GO:0016197=IEA, GO:0035091=IDA, GO:0010008=IDA, GO:0005768=IEA} cell communication, early endosome to Golgi transport, endocytosis, endosomal transport, intracellular protein transport, positive regulation of protein catabolic process Golgi apparatus, cytoplasm, cytosol, early endosome membrane, endosome, endosome membrane, intracellular membrane-bounded organelle, membrane phosphatidylinositol binding, protein binding, protein transporter activity Human SNX10 UniProtKB UniProtKB {GO:0005545=PMID:17012226, GO:0007154=GO_REF:0000002, GO:0031313=PMID:17012226, GO:0007032=PMID:17012226, GO:0015031=GO_REF:0000037, GO:0035091=GO_REF:0000002} Q9Y5X0 Sorting nexin-10 protein 20110128 {GO:0005545=IMP, GO:0007154=IEA, GO:0031313=IDA, GO:0007032=IMP, GO:0015031=IEA, GO:0035091=IEA} cell communication, endosome organization, protein transport extrinsic to endosome membrane 1-phosphatidylinositol binding, phosphatidylinositol binding Human SNX11 UniProtKB UniProtKB {GO:0007154=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0035091=GO_REF:0000002} Q9Y5W9 Sorting nexin-11 protein 20130413 {GO:0007154=IEA, GO:0016020=IEA, GO:0015031=IEA, GO:0035091=IEA} cell communication, protein transport membrane phosphatidylinositol binding Human UniProtKB-SubCell:SL-0162 SNX12 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0007154=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0035091=GO_REF:0000002} Q9UMY4 Sorting nexin-12 protein 20130415 {GO:0005515=IPI, GO:0007154=IEA, GO:0016020=IEA, GO:0015031=IEA, GO:0035091=IEA} cell communication, protein transport membrane phosphatidylinositol binding, protein binding Human UniProtKB:P16333 SNX13 UniProtKB UniProtKB {GO:0043547=PMID:11729322, GO:0007154=GO_REF:0000002, GO:0031901=GO_REF:0000039, GO:0038032=GO_REF:0000002, GO:0035091=PMID:11729322, GO:0006886=PMID:11729322, GO:0005769=PMID:11729322} Q9Y5W8 Sorting nexin-13 protein 20110128 {GO:0043547=IDA, GO:0007154=IEA, GO:0031901=IEA, GO:0038032=IEA, GO:0035091=IDA, GO:0006886=IMP, GO:0005769=IDA} cell communication, intracellular protein transport, positive regulation of GTPase activity, termination of G-protein coupled receptor signaling pathway early endosome, early endosome membrane phosphatidylinositol binding Human SNX14 UniProtKB UniProtKB {GO:0007154=GO_REF:0000002, GO:0038032=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0035091=GO_REF:0000002} Q9Y5W7 Sorting nexin-14 protein 20130413 {GO:0007154=IEA, GO:0038032=IEA, GO:0016021=IEA, GO:0015031=IEA, GO:0035091=IEA} cell communication, protein transport, termination of G-protein coupled receptor signaling pathway integral to membrane phosphatidylinositol binding Human UniProtKB-KW:KW-0812 SNX15 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0007154=GO_REF:0000002, GO:0016020=PMID:11085978, GO:0008565=GO_REF:0000029, GO:0005730=GO_REF:0000052, GO:0035091=GO_REF:0000002, GO:0006886=PMID:11085978, GO:0030659=GO_REF:0000039, GO:0005829=PMID:11085978} Q9NRS6 Sorting nexin-15 protein 20111111 {GO:0005737=IDA, GO:0007154=IEA, GO:0016020=NAS, GO:0008565=NAS, GO:0005730=IDA, GO:0035091=IEA, GO:0006886=NAS, GO:0030659=IEA, GO:0005829=NAS} cell communication, intracellular protein transport cytoplasm, cytoplasmic vesicle membrane, cytosol, membrane, nucleolus phosphatidylinositol binding, protein transporter activity Human SNX16 UniProtKB UniProtKB {GO:0007154=GO_REF:0000002, GO:0005770=PMID:12813048, GO:0031313=PMID:12813048, GO:0031901=GO_REF:0000039, GO:0008333=PMID:12813048, GO:0031902=GO_REF:0000039, GO:0006622=PMID:12813048, GO:0045022=PMID:12813048, GO:0035091=PMID:12813048, GO:0005764=GO_REF:0000039, GO:0005769=PMID:12813048, GO:0042802=PMID:12813048} P57768 Sorting nexin-16 protein 20110209 {GO:0007154=IEA, GO:0005770=IDA, GO:0031313=IDA, GO:0031901=IEA, GO:0008333=IMP, GO:0031902=IEA, GO:0006622=IMP, GO:0045022=IMP, GO:0035091=IDA, GO:0005764=IEA, GO:0005769=IDA, GO:0042802=IPI} cell communication, early endosome to late endosome transport, endosome to lysosome transport, protein targeting to lysosome early endosome, early endosome membrane, extrinsic to endosome membrane, late endosome, late endosome membrane, lysosome identical protein binding, phosphatidylinositol binding Human SNX17 HPA UniProtKB {GO:0005515=PMID:17474147, GO:0006707=PMID:12169628, GO:0005794=PMID:10942595, GO:0005102=PMID:12169628, GO:0008022=PMID:11237770, GO:0006886=PMID:12169628, GO:0006898=GO_REF:0000019, GO:0005829=PMID:16712798, GO:0043231=GO_REF:0000052, GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0007154=GO_REF:0000002, GO:0016020=PMID:12169628, GO:0030100=PMID:12169628, GO:0016197=PMID:12169628, GO:0016023=PMID:16712798, GO:0035091=PMID:16712798, GO:0005769=PMID:12169628, GO:0030659=GO_REF:0000039, GO:0050750=PMID:12169628, GO:0005768=GO_REF:0000019} Q15036 Sorting nexin-17 protein 20111111 {GO:0005515=IPI, GO:0006707=IC, GO:0005794=IDA, GO:0005102=NAS, GO:0008022=IPI, GO:0006886=NAS, GO:0006898=IEA, GO:0005829=IDA, GO:0043231=IDA, GO:0007165=IEA, GO:0005737=IDA, GO:0007154=IEA, GO:0016020=NAS, GO:0030100=NAS, GO:0016197=NAS, GO:0016023=IDA, GO:0035091=IDA, GO:0005769=IDA, GO:0030659=IEA, GO:0050750=IDA, GO:0005768=IEA} cell communication, cholesterol catabolic process, endosomal transport, intracellular protein transport, receptor-mediated endocytosis, regulation of endocytosis, signal transduction Golgi apparatus, cytoplasm, cytoplasmic membrane-bounded vesicle, cytoplasmic vesicle membrane, cytosol, early endosome, endosome, intracellular membrane-bounded organelle, membrane low-density lipoprotein particle receptor binding, phosphatidylinositol binding, protein C-terminus binding, protein binding, receptor binding Human SNX18 UniProtKB UniProtKB {GO:0043547=PMID:20427313, GO:0005515=PMID:20427313, GO:0007154=GO_REF:0000002, GO:0030136=PMID:20427313, GO:0015031=GO_REF:0000037, GO:0035091=GO_REF:0000002, GO:0010008=GO_REF:0000039, GO:0006897=PMID:20427313, GO:0031234=PMID:20427313, GO:0012505=GO_REF:0000039} Q96RF0 Sorting nexin-18 protein 20110127 {GO:0043547=IDA, GO:0005515=IPI, GO:0007154=IEA, GO:0030136=IDA, GO:0015031=IEA, GO:0035091=IEA, GO:0010008=IEA, GO:0006897=IDA, GO:0031234=IDA, GO:0012505=IEA} cell communication, endocytosis, positive regulation of GTPase activity, protein transport clathrin-coated vesicle, endomembrane system, endosome membrane, extrinsic to internal side of plasma membrane phosphatidylinositol binding, protein binding colocalizes_with Human SNX19 IntAct UniProtKB {GO:0005515=PMID:16273344, GO:0007154=GO_REF:0000002, GO:0015031=GO_REF:0000037, GO:0035091=GO_REF:0000002, GO:0030659=GO_REF:0000039} Q92543 Sorting nexin-19 protein 20130415 {GO:0005515=IPI, GO:0007154=IEA, GO:0015031=IEA, GO:0035091=IEA, GO:0030659=IEA} cell communication, protein transport cytoplasmic vesicle membrane phosphatidylinositol binding, protein binding Human UniProtKB:Q16849 SNX2 HPA UniProtKB {GO:0005515=PMID:14596906, GO:0005737=PMID:11279102, GO:0007154=GO_REF:0000002, GO:0031901=GO_REF:0000039, GO:0008565=GO_REF:0000002, GO:0035091=GO_REF:0000002, GO:0006886=GO_REF:0000002, GO:0010008=PMID:15673616, GO:0006897=PMID:9819414, GO:0043231=GO_REF:0000052} O60749 Sorting nexin-2 protein 20110516 {GO:0005515=IPI, GO:0005737=IDA, GO:0007154=IEA, GO:0031901=IEA, GO:0008565=IEA, GO:0035091=IEA, GO:0006886=IEA, GO:0010008=IDA, GO:0006897=TAS, GO:0043231=IDA} cell communication, endocytosis, intracellular protein transport cytoplasm, early endosome membrane, endosome membrane, intracellular membrane-bounded organelle phosphatidylinositol binding, protein binding, protein transporter activity Human SNX20 UniProtKB UniProtKB {GO:0007154=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0035091=GO_REF:0000002, GO:0010008=GO_REF:0000039} Q7Z614 Sorting nexin-20 protein 20130413 {GO:0007154=IEA, GO:0005886=IEA, GO:0005634=IEA, GO:0015031=IEA, GO:0035091=IEA, GO:0010008=IEA} cell communication, protein transport endosome membrane, nucleus, plasma membrane phosphatidylinositol binding Human UniProtKB-SubCell:SL-0100 SNX21 UniProtKB UniProtKB {GO:0007154=GO_REF:0000002, GO:0015031=GO_REF:0000037, GO:0035091=GO_REF:0000002, GO:0030659=GO_REF:0000039} Q969T3 Sorting nexin-21 protein 20130413 {GO:0007154=IEA, GO:0015031=IEA, GO:0035091=IEA, GO:0030659=IEA} cell communication, protein transport cytoplasmic vesicle membrane phosphatidylinositol binding Human UniProtKB-SubCell:SL-0089 SNX22 UniProtKB UniProtKB {GO:0007154=GO_REF:0000002, GO:0015031=GO_REF:0000037, GO:0035091=GO_REF:0000002, GO:0030659=GO_REF:0000039} Q96L94 Sorting nexin-22 protein 20130413 {GO:0007154=IEA, GO:0015031=IEA, GO:0035091=IEA, GO:0030659=IEA} cell communication, protein transport cytoplasmic vesicle membrane phosphatidylinositol binding Human UniProtKB-SubCell:SL-0089 SNX24 UniProtKB UniProtKB {GO:0007154=GO_REF:0000002, GO:0015031=GO_REF:0000037, GO:0035091=GO_REF:0000002, GO:0030659=GO_REF:0000039} Q9Y343 Sorting nexin-24 protein 20130413 {GO:0007154=IEA, GO:0015031=IEA, GO:0035091=IEA, GO:0030659=IEA} cell communication, protein transport cytoplasmic vesicle membrane phosphatidylinositol binding Human UniProtKB-SubCell:SL-0089 SNX25 UniProtKB UniProtKB {GO:0007154=GO_REF:0000002, GO:0038032=GO_REF:0000002, GO:0015031=GO_REF:0000037, GO:0035091=GO_REF:0000002, GO:0010008=GO_REF:0000039} Q9H3E2 Sorting nexin-25 protein 20130413 {GO:0007154=IEA, GO:0038032=IEA, GO:0015031=IEA, GO:0035091=IEA, GO:0010008=IEA} cell communication, protein transport, termination of G-protein coupled receptor signaling pathway endosome membrane phosphatidylinositol binding Human UniProtKB-SubCell:SL-0100 SNX27 HPA UniProtKB {GO:0005515=PMID:19555689, GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0008333=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0015031=GO_REF:0000037, GO:0035091=GO_REF:0000002, GO:0005769=GO_REF:0000039, GO:0005829=GO_REF:0000039} Q96L92 Sorting nexin-27 protein 20111111 {GO:0005515=IPI, GO:0007165=IEA, GO:0005737=IDA, GO:0008333=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0015031=IEA, GO:0035091=IEA, GO:0005769=IEA, GO:0005829=IEA} endosome to lysosome transport, protein transport, signal transduction cytoplasm, cytosol, early endosome, nucleolus, nucleus phosphatidylinositol binding, protein binding Human SNX29 InterPro UniProtKB {GO:0007154=GO_REF:0000002, GO:0035091=GO_REF:0000002} Q8TEQ0 Sorting nexin-29 protein 20130413 {GO:0007154=IEA, GO:0035091=IEA} cell communication phosphatidylinositol binding Human InterPro:IPR001683 SNX3 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0005737=PMID:11279102, GO:0007154=GO_REF:0000002, GO:0019903=PMID:17622474, GO:0032266=PMID:11433298, GO:0015031=GO_REF:0000037, GO:0010008=PMID:15673616, GO:0005769=PMID:11433298, GO:0006897=PMID:9819414} O60493 Sorting nexin-3 protein 20130415 {GO:0005515=IPI, GO:0005737=IDA, GO:0007154=IEA, GO:0019903=IPI, GO:0032266=IDA, GO:0015031=IEA, GO:0010008=IDA, GO:0005769=IDA, GO:0006897=TAS} cell communication, endocytosis, protein transport cytoplasm, early endosome, endosome membrane phosphatidylinositol-3-phosphate binding, protein binding, protein phosphatase binding Human UniProtKB:P46108 SNX30 UniProtKB UniProtKB {GO:0005737=GO_REF:0000002, GO:0007154=GO_REF:0000002, GO:0015031=GO_REF:0000037, GO:0035091=GO_REF:0000002} Q5VWJ9 Sorting nexin-30 protein 20130413 {GO:0005737=IEA, GO:0007154=IEA, GO:0015031=IEA, GO:0035091=IEA} cell communication, protein transport cytoplasm phosphatidylinositol binding Human UniProtKB-KW:KW-0653 SNX32 UniProtKB UniProtKB {GO:0007154=GO_REF:0000002, GO:0015031=GO_REF:0000037, GO:0035091=GO_REF:0000002} Q86XE0 Sorting nexin-32 protein 20130413 {GO:0007154=IEA, GO:0015031=IEA, GO:0035091=IEA} cell communication, protein transport phosphatidylinositol binding Human UniProtKB-KW:KW-0653 SNX33 IntAct UniProtKB {GO:0005515=PMID:19807924, GO:0007154=GO_REF:0000002, GO:0035091=GO_REF:0000002} Q8WV41 Sorting nexin-33 protein 20130415 {GO:0005515=IPI, GO:0007154=IEA, GO:0035091=IEA} cell communication phosphatidylinositol binding, protein binding Human UniProtKB:P48023 SNX4 HGNC UniProtKB {GO:0005515=PMID:11279102, GO:0005737=PMID:11279102, GO:0007154=GO_REF:0000002, GO:0031901=PMID:17994011, GO:0032456=PMID:17994011, GO:0005868=PMID:17994011, GO:0015031=PMID:17994011, GO:0035091=PMID:17994011, GO:0006897=PMID:9819414} O95219 Sorting nexin-4 protein 20061026 {GO:0005515=IPI, GO:0005737=IDA, GO:0007154=IEA, GO:0031901=IDA, GO:0032456=IMP, GO:0005868=IDA, GO:0015031=IMP, GO:0035091=IMP, GO:0006897=TAS} cell communication, endocytic recycling, endocytosis, protein transport cytoplasm, cytoplasmic dynein complex, early endosome membrane phosphatidylinositol binding, protein binding Human UniProtKB:Q9UNH7 SNX5 UniProtKB UniProtKB {GO:0006907=PMID:18854019, GO:0007154=GO_REF:0000002, GO:0031901=PMID:15561769, GO:0031313=PMID:15561769, GO:0070685=PMID:18854019, GO:0001891=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0035091=PMID:15561769, GO:0001726=GO_REF:0000039, GO:0030659=GO_REF:0000039, GO:0031234=PMID:15561769} Q9Y5X3 Sorting nexin-5 protein 20110112 {GO:0006907=IDA, GO:0007154=IEA, GO:0031901=IDA, GO:0031313=IDA, GO:0070685=IDA, GO:0001891=IEA, GO:0015031=IEA, GO:0035091=IDA, GO:0001726=IEA, GO:0030659=IEA, GO:0031234=IDA} cell communication, pinocytosis, protein transport cytoplasmic vesicle membrane, early endosome membrane, extrinsic to endosome membrane, extrinsic to internal side of plasma membrane, macropinocytic cup, phagocytic cup, ruffle phosphatidylinositol binding Human SNX6 HPA UniProtKB {GO:0005515=PMID:11279102, GO:0005634=GO_REF:0000039, GO:0006886=PMID:19935774, GO:0042803=PMID:11279102, GO:0043231=GO_REF:0000052, GO:0005622=PMID:11279102, GO:0005737=PMID:11279102, GO:0007154=GO_REF:0000002, GO:0007175=PMID:11279102, GO:0031901=PMID:19935774, GO:0042147=PMID:19935774, GO:0035091=GO_REF:0000002, GO:0045892=PMID:11279102, GO:0030512=PMID:11279102, GO:0030659=GO_REF:0000039} Q9UNH7 Sorting nexin-6 protein 20120912 {GO:0005515=IPI, GO:0005634=IEA, GO:0006886=IMP, GO:0042803=IPI, GO:0043231=IDA, GO:0005622=NAS, GO:0005737=IDA, GO:0007154=IEA, GO:0007175=NAS, GO:0031901=IDA, GO:0042147=IMP, GO:0035091=IEA, GO:0045892=IDA, GO:0030512=IDA, GO:0030659=IEA} cell communication, intracellular protein transport, negative regulation of epidermal growth factor-activated receptor activity, negative regulation of transcription, DNA-dependent, negative regulation of transforming growth factor beta receptor signaling pathway, retrograde transport, endosome to Golgi cytoplasm, cytoplasmic vesicle membrane, early endosome membrane, intracellular, intracellular membrane-bounded organelle, nucleus phosphatidylinositol binding, protein binding, protein homodimerization activity Human SNX7 UniProtKB UniProtKB {GO:0007154=GO_REF:0000002, GO:0015031=GO_REF:0000037, GO:0035091=GO_REF:0000002, GO:0030659=GO_REF:0000039} Q9UNH6 Sorting nexin-7 protein 20130413 {GO:0007154=IEA, GO:0015031=IEA, GO:0035091=IEA, GO:0030659=IEA} cell communication, protein transport cytoplasmic vesicle membrane phosphatidylinositol binding Human UniProtKB-SubCell:SL-0089 SNX8 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0007154=GO_REF:0000002, GO:0034498=PMID:19782049, GO:0031901=PMID:19782049, GO:0035091=PMID:19782049, GO:0006886=PMID:19782049, GO:0030904=PMID:19782049} Q9Y5X2 Sorting nexin-8 protein 20130415 {GO:0005515=IPI, GO:0007154=IEA, GO:0034498=IMP, GO:0031901=IDA, GO:0035091=IMP, GO:0006886=IMP, GO:0030904=IDA} cell communication, early endosome to Golgi transport, intracellular protein transport early endosome membrane, retromer complex phosphatidylinositol binding, protein binding Human UniProtKB:P16333 SNX9 BHF-UCL UniProtKB {GO:0005515=PMID:10531379, GO:0005802=PMID:15703209, GO:0005794=GO_REF:0000039, GO:0005886=GO_REF:0000019, GO:0030136=PMID:15703209, GO:0006886=PMID:15703209, GO:0001726=GO_REF:0000039, GO:0042803=PMID:17948057, GO:0006898=PMID:15703209, GO:0031234=PMID:15703209, GO:0043547=PMID:15703209, GO:0005545=PMID:17948057, GO:0060988=PMID:17948057, GO:0005737=GO_REF:0000019, GO:0007154=GO_REF:0000002, GO:0016023=PMID:15703209, GO:0032461=PMID:15703209, GO:0035091=GO_REF:0000019, GO:0031625=PMID:20491914, GO:0030659=PMID:17948057} Q9Y5X1 Sorting nexin-9 protein 20081114 {GO:0005515=IPI, GO:0005802=IDA, GO:0005794=IEA, GO:0005886=IEA, GO:0030136=IDA, GO:0006886=IMP, GO:0001726=IEA, GO:0042803=IPI, GO:0006898=IMP, GO:0031234=IDA, GO:0043547=IDA, GO:0005545=IDA, GO:0060988=IDA, GO:0005737=IEA, GO:0007154=IEA, GO:0016023=IDA, GO:0032461=IDA, GO:0035091=IEA, GO:0031625=IPI, GO:0030659=IDA} cell communication, intracellular protein transport, lipid tube assembly, positive regulation of GTPase activity, positive regulation of protein oligomerization, receptor-mediated endocytosis Golgi apparatus, clathrin-coated vesicle, cytoplasm, cytoplasmic membrane-bounded vesicle, cytoplasmic vesicle membrane, extrinsic to internal side of plasma membrane, plasma membrane, ruffle, trans-Golgi network 1-phosphatidylinositol binding, phosphatidylinositol binding, protein binding, protein homodimerization activity, ubiquitin protein ligase binding Human UniProtKB:Q61072 SOAT1 BHF-UCL UniProtKB {GO:0042632=PMID:11401500, GO:0033344=PMID:15308631, GO:0010878=PMID:8407899, GO:0005783=PMID:10623671, GO:0010742=PMID:18971559, GO:0034379=PMID:15308631, GO:0042986=PMID:17412327, GO:0034736=PMID:8407899, GO:0016020=PMID:9756919, GO:0015485=PMID:16647063, GO:0004772=PMID:8407899, GO:0005789=PMID:17412327, GO:0016021=GO_REF:0000037, GO:0034435=PMID:16647063, GO:0000062=PMID:16647063, GO:0008203=PMID:8407899} P35610 Sterol O-acyltransferase 1 protein 20090209 {GO:0042632=TAS, GO:0033344=IMP, GO:0010878=IMP, GO:0005783=IDA, GO:0010742=NAS, GO:0034379=IMP, GO:0042986=IMP, GO:0034736=IMP, GO:0016020=IDA, GO:0015485=IDA, GO:0004772=IMP, GO:0005789=IDA, GO:0016021=IEA, GO:0034435=IDA, GO:0000062=IDA, GO:0008203=IMP} cholesterol efflux, cholesterol esterification, cholesterol homeostasis, cholesterol metabolic process, cholesterol storage, macrophage derived foam cell differentiation, positive regulation of amyloid precursor protein biosynthetic process, very-low-density lipoprotein particle assembly endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, membrane cholesterol O-acyltransferase activity, cholesterol binding, fatty-acyl-CoA binding, sterol O-acyltransferase activity Human SOAT2 BHF-UCL UniProtKB {GO:0042632=PMID:11401500, GO:0008374=GO_REF:0000002, GO:0033344=PMID:15308631, GO:0016746=PMID:9756920, GO:0005783=PMID:15451793, GO:0010742=PMID:14615411, GO:0034379=PMID:15308631, GO:0030299=PMID:14615411, GO:0005903=PMID:14615411, GO:0034736=PMID:16647063, GO:0015485=PMID:16647063, GO:0005789=PMID:12808042, GO:0016021=GO_REF:0000037, GO:0034435=PMID:16647063, GO:0000062=PMID:16647063, GO:0008203=PMID:16647063} O75908 Sterol O-acyltransferase 2 protein 20090209 {GO:0042632=TAS, GO:0008374=IEA, GO:0033344=IMP, GO:0016746=TAS, GO:0005783=IDA, GO:0010742=TAS, GO:0034379=IMP, GO:0030299=IC, GO:0005903=IDA, GO:0034736=IDA, GO:0015485=IDA, GO:0005789=IDA, GO:0016021=IEA, GO:0034435=IDA, GO:0000062=IDA, GO:0008203=IDA} cholesterol efflux, cholesterol esterification, cholesterol homeostasis, cholesterol metabolic process, intestinal cholesterol absorption, macrophage derived foam cell differentiation, very-low-density lipoprotein particle assembly brush border, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane O-acyltransferase activity, cholesterol O-acyltransferase activity, cholesterol binding, fatty-acyl-CoA binding, transferase activity, transferring acyl groups Human GO:0005903 SOBP UniProtKB UniProtKB {GO:0042472=GO_REF:0000019, GO:0032184=PMID:23086935, GO:0007605=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0046872=GO_REF:0000037} A7XYQ1 Sine oculis-binding protein homolog protein 20121130 {GO:0042472=IEA, GO:0032184=IDA, GO:0007605=IEA, GO:0007626=IEA, GO:0046872=IEA} inner ear morphogenesis, locomotory behavior, sensory perception of sound SUMO polymer binding, metal ion binding Human SOCS1 GOC UniProtKB {GO:0005515=PMID:17183367, GO:0016567=GO_REF:0000041, GO:0005159=PMID:9727029, GO:0019221=Reactome:REACT_25229, GO:0005634=GO_REF:0000039, GO:0060397=Reactome:REACT_111133, GO:0005829=Reactome:REACT_111181, GO:0060334=Reactome:REACT_24980, GO:0005737=PMID:9202126, GO:0060337=Reactome:REACT_25162, GO:0071230=GO_REF:0000019, GO:0060338=Reactome:REACT_25216, GO:0045444=GO_REF:0000019, GO:0060333=Reactome:REACT_25078, GO:0042518=GO_REF:0000024, GO:0019901=PMID:9727029, GO:0019210=GO_REF:0000024, GO:0046627=GO_REF:0000024, GO:0007259=PMID:9202126, GO:0046426=PMID:9727029, GO:0004860=PMID:9202125, GO:0016023=GO_REF:0000039, GO:0001932=GO_REF:0000024, GO:0006469=PMID:9202125, GO:0040008=GO_REF:0000037} O15524 Suppressor of cytokine signaling 1 protein 20130413 {GO:0005515=IPI, GO:0016567=IEA, GO:0005159=IPI, GO:0019221=TAS, GO:0005634=IEA, GO:0060397=TAS, GO:0005829=TAS, GO:0060334=TAS, GO:0005737=TAS, GO:0060337=TAS, GO:0071230=IEA, GO:0060338=TAS, GO:0045444=IEA, GO:0060333=TAS, GO:0042518=ISS, GO:0019901=IPI, GO:0019210=ISS, GO:0046627=ISS, GO:0007259=TAS, GO:0046426=NAS, GO:0004860=TAS, GO:0016023=IEA, GO:0001932=ISS, GO:0006469=TAS, GO:0040008=IEA} JAK-STAT cascade, JAK-STAT cascade involved in growth hormone signaling pathway, cellular response to amino acid stimulus, cytokine-mediated signaling pathway, fat cell differentiation, interferon-gamma-mediated signaling pathway, negative regulation of JAK-STAT cascade, negative regulation of insulin receptor signaling pathway, negative regulation of protein kinase activity, negative regulation of tyrosine phosphorylation of Stat3 protein, protein ubiquitination, regulation of growth, regulation of interferon-gamma-mediated signaling pathway, regulation of protein phosphorylation, regulation of type I interferon-mediated signaling pathway, type I interferon-mediated signaling pathway cytoplasm, cytoplasmic membrane-bounded vesicle, cytosol, nucleus insulin-like growth factor receptor binding, kinase inhibitor activity, protein binding, protein kinase binding, protein kinase inhibitor activity Human SOCS2 GOC UniProtKB {GO:0005515=PMID:11781573, GO:0043066=PMID:9266833, GO:0016567=GO_REF:0000041, GO:0005148=GO_REF:0000029, GO:0005159=PMID:9727029, GO:0007568=GO_REF:0000019, GO:0005131=PMID:12135564, GO:0046425=PMID:9266833, GO:0043434=GO_REF:0000019, GO:0060396=PMID:12552091, GO:0060397=Reactome:REACT_111133, GO:0009966=PMID:9727029, GO:0001558=PMID:9727029, GO:0007259=PMID:9266833, GO:0032870=PMID:12552091, GO:0005829=Reactome:REACT_111181, GO:0005737=PMID:9727029, GO:0008269=PMID:9266833, GO:0005070=PMID:9344848, GO:0009968=GO_REF:0000037, GO:0032355=PMID:12552091} O14508 Suppressor of cytokine signaling 2 protein 20130413 {GO:0005515=IPI, GO:0043066=TAS, GO:0016567=IEA, GO:0005148=NAS, GO:0005159=IPI, GO:0007568=IEA, GO:0005131=NAS, GO:0046425=TAS, GO:0043434=IEA, GO:0060396=IDA, GO:0060397=TAS, GO:0009966=NAS, GO:0001558=NAS, GO:0007259=TAS, GO:0032870=IDA, GO:0005829=TAS, GO:0005737=NAS, GO:0008269=TAS, GO:0005070=TAS, GO:0009968=IEA, GO:0032355=IDA} JAK-STAT cascade, JAK-STAT cascade involved in growth hormone signaling pathway, aging, cellular response to hormone stimulus, growth hormone receptor signaling pathway, negative regulation of apoptotic process, negative regulation of signal transduction, protein ubiquitination, regulation of JAK-STAT cascade, regulation of cell growth, regulation of signal transduction, response to estradiol stimulus, response to peptide hormone stimulus cytoplasm, cytosol JAK pathway signal transduction adaptor activity, SH3/SH2 adaptor activity, growth hormone receptor binding, insulin-like growth factor receptor binding, prolactin receptor binding, protein binding Human SOCS3 GOC UniProtKB {GO:0043066=PMID:9266833, GO:0060674=GO_REF:0000019, GO:0016567=GO_REF:0000041, GO:0046627=GO_REF:0000019, GO:0060708=GO_REF:0000019, GO:0045597=GO_REF:0000019, GO:0060670=GO_REF:0000019, GO:0060707=GO_REF:0000019, GO:0019221=Reactome:REACT_25229, GO:0060397=Reactome:REACT_111133, GO:0007259=PMID:9266833, GO:0005829=Reactome:REACT_111181, GO:0060334=Reactome:REACT_24980, GO:0060337=Reactome:REACT_25162, GO:0060338=Reactome:REACT_25216, GO:0004860=PMID:9266833, GO:0006469=PMID:9266833, GO:0040008=GO_REF:0000037, GO:0060333=Reactome:REACT_25078} O14543 Suppressor of cytokine signaling 3 protein 20130413 {GO:0043066=TAS, GO:0060674=IEA, GO:0016567=IEA, GO:0046627=IEA, GO:0060708=IEA, GO:0045597=IEA, GO:0060670=IEA, GO:0060707=IEA, GO:0019221=TAS, GO:0060397=TAS, GO:0007259=TAS, GO:0005829=TAS, GO:0060334=TAS, GO:0060337=TAS, GO:0060338=TAS, GO:0004860=TAS, GO:0006469=TAS, GO:0040008=IEA, GO:0060333=TAS} JAK-STAT cascade, JAK-STAT cascade involved in growth hormone signaling pathway, branching involved in labyrinthine layer morphogenesis, cytokine-mediated signaling pathway, interferon-gamma-mediated signaling pathway, negative regulation of apoptotic process, negative regulation of insulin receptor signaling pathway, negative regulation of protein kinase activity, placenta blood vessel development, positive regulation of cell differentiation, protein ubiquitination, regulation of growth, regulation of interferon-gamma-mediated signaling pathway, regulation of type I interferon-mediated signaling pathway, spongiotrophoblast differentiation, trophoblast giant cell differentiation, type I interferon-mediated signaling pathway cytosol protein kinase inhibitor activity Human SOCS4 UniProtKB UniProtKB {GO:0035556=GO_REF:0000002, GO:0016567=GO_REF:0000041, GO:0007175=PMID:15590694, GO:0040008=GO_REF:0000037} Q8WXH5 Suppressor of cytokine signaling 4 protein 20111012 {GO:0035556=IEA, GO:0016567=IEA, GO:0007175=IDA, GO:0040008=IEA} intracellular signal transduction, negative regulation of epidermal growth factor-activated receptor activity, protein ubiquitination, regulation of growth Human SOCS5 UniProtKB UniProtKB {GO:0005515=PMID:15590694, GO:0030971=PMID:15590694, GO:0005154=GO_REF:0000019, GO:0016567=GO_REF:0000041, GO:0019221=GO_REF:0000024, GO:0032436=PMID:15590694, GO:0035556=GO_REF:0000002, GO:0007173=GO_REF:0000019, GO:0045629=GO_REF:0000024, GO:0007175=PMID:15590694, GO:0045627=GO_REF:0000024, GO:0016049=PMID:11837794, GO:0009968=PMID:10773671, GO:0040008=GO_REF:0000037} O75159 Suppressor of cytokine signaling 5 protein 20111012 {GO:0005515=IPI, GO:0030971=IPI, GO:0005154=IEA, GO:0016567=IEA, GO:0019221=ISS, GO:0032436=IMP, GO:0035556=IEA, GO:0007173=IEA, GO:0045629=ISS, GO:0007175=IDA, GO:0045627=ISS, GO:0016049=NAS, GO:0009968=NAS, GO:0040008=IEA} cell growth, cytokine-mediated signaling pathway, epidermal growth factor receptor signaling pathway, intracellular signal transduction, negative regulation of T-helper 2 cell differentiation, negative regulation of epidermal growth factor-activated receptor activity, negative regulation of signal transduction, positive regulation of T-helper 1 cell differentiation, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, protein ubiquitination, regulation of growth epidermal growth factor receptor binding, protein binding, receptor tyrosine kinase binding Human SOCS6 MGI UniProtKB {GO:0001772=PMID:20007709, GO:0005737=PMID:9344848, GO:0016567=GO_REF:0000041, GO:0050868=GO_REF:0000019, GO:0006952=PMID:9344848, GO:0009968=GO_REF:0000037, GO:0007259=PMID:9344848, GO:0010498=PMID:20007709, GO:0040008=GO_REF:0000019} O14544 Suppressor of cytokine signaling 6 protein 20120831 {GO:0001772=IDA, GO:0005737=TAS, GO:0016567=IEA, GO:0050868=IEA, GO:0006952=TAS, GO:0009968=IEA, GO:0007259=TAS, GO:0010498=IMP, GO:0040008=IEA} JAK-STAT cascade, defense response, negative regulation of T cell activation, negative regulation of signal transduction, proteasomal protein catabolic process, protein ubiquitination, regulation of growth cytoplasm, immunological synapse Human SOCS7 HPA UniProtKB {GO:0008286=GO_REF:0000019, GO:0035556=GO_REF:0000002, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0017124=PMID:9344857, GO:0016567=GO_REF:0000041, GO:0005886=GO_REF:0000039, GO:0045444=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0009968=GO_REF:0000037, GO:0040008=GO_REF:0000037} O14512 Suppressor of cytokine signaling 7 protein 20090616 {GO:0008286=IEA, GO:0035556=IEA, GO:0008150=ND, GO:0005737=IDA, GO:0017124=NAS, GO:0016567=IEA, GO:0005886=IEA, GO:0045444=IEA, GO:0005634=IEA, GO:0009968=IEA, GO:0040008=IEA} biological_process, fat cell differentiation, insulin receptor signaling pathway, intracellular signal transduction, negative regulation of signal transduction, protein ubiquitination, regulation of growth cytoplasm, nucleus, plasma membrane SH3 domain binding Human SOD1 HPA UniProtKB {GO:0005515=PMID:16369483, GO:0045859=PMID:16254550, GO:0042542=GO_REF:0000024, GO:0030346=PMID:17324120, GO:0008090=PMID:20510358, GO:0060047=PMID:9539776, GO:0009408=GO_REF:0000024, GO:0007605=GO_REF:0000024, GO:0006801=GO_REF:0000024, GO:0060088=GO_REF:0000024, GO:0006749=GO_REF:0000024, GO:0033081=PMID:16716898, GO:0048538=PMID:16716898, GO:0007283=GO_REF:0000024, GO:0001819=PMID:15544046, GO:0019226=GO_REF:0000024, GO:0048678=GO_REF:0000024, GO:0005615=PMID:9453566, GO:0042803=PMID:10837872, GO:0060087=GO_REF:0000024, GO:0006879=GO_REF:0000024, GO:0043524=GO_REF:0000024, GO:0001895=GO_REF:0000024, GO:0005759=PMID:17008312, GO:0019430=GO_REF:0000024, GO:0043025=PMID:17324120, GO:0031667=GO_REF:0000019, GO:0002262=GO_REF:0000024, GO:0004784=PMID:15544046, GO:0007566=PMID:10920331, GO:0005507=PMID:17008312, GO:0007569=PMID:12871978, GO:0030168=Reactome:REACT_798, GO:0001890=PMID:12485882, GO:0043085=PMID:17324120, GO:0043234=PMID:17324120, GO:0008270=PMID:17381088, GO:0000303=PMID:16790527, GO:0008089=PMID:20510358, GO:0046688=GO_REF:0000019, GO:0005886=PMID:17324120, GO:0045471=GO_REF:0000024, GO:0045541=PMID:15473258, GO:0051087=PMID:9726962, GO:0032839=PMID:17324120, GO:0005634=GO_REF:0000052, GO:0050665=PMID:15544046, GO:0046716=GO_REF:0000024, GO:0046872=GO_REF:0000038, GO:0006302=GO_REF:0000024, GO:0005829=Reactome:REACT_21347, GO:0005739=PMID:16790527, GO:0000187=GO_REF:0000024, GO:0001541=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0040014=GO_REF:0000024, GO:0007626=GO_REF:0000024, GO:0005777=GO_REF:0000024, GO:0042554=GO_REF:0000019, GO:0046620=PMID:16716898, GO:0060052=GO_REF:0000024, GO:0043065=PMID:16790527, GO:0010033=PMID:12921788, GO:0042493=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0051881=PMID:16790527, GO:0005576=Reactome:REACT_21347, GO:0031410=PMID:17077646, GO:0032287=GO_REF:0000024, GO:0031012=PMID:9699963, GO:0001975=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0006309=GO_REF:0000024, GO:0002576=Reactome:REACT_318, GO:0008217=GO_REF:0000024} P00441 "Superoxide dismutase ""Cu-Zn""" protein 20101115 {GO:0005515=IPI, GO:0045859=IDA, GO:0042542=ISS, GO:0030346=IDA, GO:0008090=ISS, GO:0060047=IDA, GO:0009408=ISS, GO:0007605=ISS, GO:0006801=ISS, GO:0060088=ISS, GO:0006749=ISS, GO:0033081=NAS, GO:0048538=NAS, GO:0007283=ISS, GO:0001819=IDA, GO:0019226=ISS, GO:0048678=ISS, GO:0005615=IDA, GO:0042803=NAS, GO:0060087=ISS, GO:0006879=ISS, GO:0043524=ISS, GO:0001895=ISS, GO:0005759=NAS, GO:0019430=ISS, GO:0043025=IDA, GO:0031667=IEA, GO:0002262=ISS, GO:0004784=IDA, GO:0007566=NAS, GO:0005507=IDA, GO:0007569=IMP, GO:0030168=TAS, GO:0001890=NAS, GO:0043085=IDA, GO:0043234=IDA, GO:0008270=IDA, GO:0000303=IDA, GO:0008089=ISS, GO:0046688=IEA, GO:0005886=IDA, GO:0045471=ISS, GO:0045541=IDA, GO:0051087=IPI, GO:0032839=IDA, GO:0005634=IDA, GO:0050665=IDA, GO:0046716=ISS, GO:0046872=IEA, GO:0006302=ISS, GO:0005829=TAS, GO:0005739=IDA, GO:0000187=ISS, GO:0001541=ISS, GO:0005737=IDA, GO:0040014=ISS, GO:0007626=ISS, GO:0005777=ISS, GO:0042554=IEA, GO:0046620=NAS, GO:0060052=ISS, GO:0043065=IC, GO:0010033=IDA, GO:0042493=ISS, GO:0005730=IDA, GO:0051881=IMP, GO:0005576=TAS, GO:0031410=IDA, GO:0032287=ISS, GO:0031012=IDA, GO:0001975=IEA, GO:0007596=TAS, GO:0006309=ISS, GO:0002576=TAS, GO:0008217=ISS} activation of MAPK activity, anterograde axon cargo transport, apoptotic DNA fragmentation, auditory receptor cell stereocilium organization, blood coagulation, cell aging, cellular iron ion homeostasis, double-strand break repair, embryo implantation, glutathione metabolic process, heart contraction, hydrogen peroxide biosynthetic process, locomotory behavior, muscle cell homeostasis, myeloid cell homeostasis, negative regulation of cholesterol biosynthetic process, negative regulation of neuron apoptotic process, neurofilament cytoskeleton organization, ovarian follicle development, peripheral nervous system myelin maintenance, placenta development, platelet activation, platelet degranulation, positive regulation of apoptotic process, positive regulation of catalytic activity, positive regulation of cytokine production, regulation of T cell differentiation in thymus, regulation of blood pressure, regulation of mitochondrial membrane potential, regulation of multicellular organism growth, regulation of organ growth, regulation of protein kinase activity, relaxation of vascular smooth muscle, removal of superoxide radicals, response to amphetamine, response to axon injury, response to copper ion, response to drug, response to ethanol, response to heat, response to hydrogen peroxide, response to nutrient levels, response to organic substance, response to superoxide, retina homeostasis, retrograde axon cargo transport, sensory perception of sound, spermatogenesis, superoxide anion generation, superoxide metabolic process, thymus development, transmission of nerve impulse cytoplasm, cytoplasmic vesicle, cytosol, dendrite cytoplasm, extracellular matrix, extracellular region, extracellular space, mitochondrial matrix, mitochondrion, neuronal cell body, nucleolus, nucleus, peroxisome, plasma membrane, protein complex chaperone binding, copper ion binding, metal ion binding, protein binding, protein homodimerization activity, protein phosphatase 2B binding, superoxide dismutase activity, zinc ion binding Human SOD2 BHF-UCL UniProtKB {GO:0042645=GO_REF:0000019, GO:0042542=GO_REF:0000019, GO:0045599=GO_REF:0000019, GO:0006801=PMID:12551919, GO:0006749=GO_REF:0000019, GO:0034021=GO_REF:0000019, GO:0033591=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0010043=GO_REF:0000019, GO:0048678=GO_REF:0000019, GO:0010042=GO_REF:0000019, GO:0042802=GO_REF:0000019, GO:0007507=GO_REF:0000019, GO:0043524=PMID:17251466, GO:0005759=PMID:10511315, GO:0019430=PMID:16179351, GO:0051602=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0051260=GO_REF:0000019, GO:0010332=GO_REF:0000019, GO:0001315=PMID:14980699, GO:0004784=PMID:12551919, GO:0001889=GO_REF:0000019, GO:0003032=GO_REF:0000019, GO:0055093=GO_REF:0000019, GO:0000303=PMID:16179351, GO:0032364=PMID:16179351, GO:0001306=GO_REF:0000019, GO:0046686=GO_REF:0000019, GO:0008285=PMID:16179351, GO:0048773=GO_REF:0000019, GO:0005743=GO_REF:0000019, GO:0048147=GO_REF:0000019, GO:0001836=GO_REF:0000024, GO:0050665=GO_REF:0000019, GO:0055072=GO_REF:0000019, GO:0046872=GO_REF:0000002, GO:0045429=GO_REF:0000019, GO:0005739=PMID:12551919, GO:0051289=PMID:19265433, GO:0048666=GO_REF:0000019, GO:0003069=GO_REF:0000024, GO:0007626=GO_REF:0000019, GO:0030097=GO_REF:0000019, GO:0042554=GO_REF:0000019, GO:0014823=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0043066=PMID:12551919, GO:0030145=PMID:10511315, GO:0006357=PMID:9393747, GO:0042493=GO_REF:0000019, GO:0051881=GO_REF:0000019, GO:0010269=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0022904=GO_REF:0000019, GO:0050790=GO_REF:0000019, GO:0071361=GO_REF:0000019, GO:0019825=GO_REF:0000019, GO:0008217=GO_REF:0000024} P04179 "Superoxide dismutase ""Mn"", mitochondrial" protein 20080915 {GO:0042645=IEA, GO:0042542=IEA, GO:0045599=IEA, GO:0006801=IMP, GO:0006749=IEA, GO:0034021=IEA, GO:0033591=IEA, GO:0009791=IEA, GO:0010043=IEA, GO:0048678=IEA, GO:0010042=IEA, GO:0042802=IEA, GO:0007507=IEA, GO:0043524=IGI, GO:0005759=TAS, GO:0019430=IMP, GO:0051602=IEA, GO:0032496=IEA, GO:0051260=IEA, GO:0010332=IEA, GO:0001315=IMP, GO:0004784=IMP, GO:0001889=IEA, GO:0003032=IEA, GO:0055093=IEA, GO:0000303=IMP, GO:0032364=IMP, GO:0001306=IEA, GO:0046686=IEA, GO:0008285=IMP, GO:0048773=IEA, GO:0005743=IEA, GO:0048147=IEA, GO:0001836=ISS, GO:0050665=IEA, GO:0055072=IEA, GO:0046872=IEA, GO:0045429=IEA, GO:0005739=IDA, GO:0051289=IPI, GO:0048666=IEA, GO:0003069=ISS, GO:0007626=IEA, GO:0030097=IEA, GO:0042554=IEA, GO:0014823=IEA, GO:0001666=IEA, GO:0043066=IMP, GO:0030145=TAS, GO:0006357=IMP, GO:0042493=IEA, GO:0051881=IEA, GO:0010269=IEA, GO:0003677=IEA, GO:0022904=IEA, GO:0050790=IEA, GO:0071361=IEA, GO:0019825=IEA, GO:0008217=ISS} age-dependent response to oxidative stress, age-dependent response to reactive oxygen species, cellular response to ethanol, detection of oxygen, erythrophore differentiation, glutathione metabolic process, heart development, hemopoiesis, hydrogen peroxide biosynthetic process, iron ion homeostasis, liver development, locomotory behavior, negative regulation of apoptotic process, negative regulation of cell proliferation, negative regulation of fat cell differentiation, negative regulation of fibroblast proliferation, negative regulation of neuron apoptotic process, neuron development, oxygen homeostasis, positive regulation of nitric oxide biosynthetic process, post-embryonic development, protein homooligomerization, protein homotetramerization, regulation of blood pressure, regulation of catalytic activity, regulation of mitochondrial membrane potential, regulation of transcription from RNA polymerase II promoter, release of cytochrome c from mitochondria, removal of superoxide radicals, respiratory electron transport chain, response to L-ascorbic acid, response to activity, response to axon injury, response to cadmium ion, response to drug, response to electrical stimulus, response to gamma radiation, response to hydrogen peroxide, response to hyperoxia, response to hypoxia, response to lipopolysaccharide, response to manganese ion, response to selenium ion, response to silicon dioxide, response to superoxide, response to zinc ion, superoxide anion generation, superoxide metabolic process, vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure mitochondrial inner membrane, mitochondrial matrix, mitochondrial nucleoid, mitochondrion DNA binding, identical protein binding, manganese ion binding, metal ion binding, oxygen binding, superoxide dismutase activity Human SOD3 BHF-UCL UniProtKB {GO:0005802=GO_REF:0000019, GO:0005515=PMID:15528465, GO:0001666=GO_REF:0000019, GO:0005507=GO_REF:0000033, GO:0006801=GO_REF:0000002, GO:0005634=GO_REF:0000033, GO:0005829=GO_REF:0000033, GO:0005739=GO_REF:0000033, GO:0019430=GO_REF:0000033, GO:0008270=GO_REF:0000033, GO:0046688=GO_REF:0000019, GO:0008201=GO_REF:0000037, GO:0004784=GO_REF:0000033} P08294 "Extracellular superoxide dismutase ""Cu-Zn""" protein 20101007 {GO:0005802=IEA, GO:0005515=IPI, GO:0001666=IEA, GO:0005507=IBA, GO:0006801=IEA, GO:0005634=IBA, GO:0005829=IBA, GO:0005739=IBA, GO:0019430=IBA, GO:0008270=IBA, GO:0046688=IEA, GO:0008201=IEA, GO:0004784=IBA} removal of superoxide radicals, response to copper ion, response to hypoxia, superoxide metabolic process cytosol, mitochondrion, nucleus, trans-Golgi network copper ion binding, heparin binding, protein binding, superoxide dismutase activity, zinc ion binding Human UniProtKB:Q9UBX5 SOHLH2 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0048477=GO_REF:0000037, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9NX45 Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2 protein 20130413 {GO:0006355=IEA, GO:0048477=IEA, GO:0046983=IEA, GO:0005634=IEA, GO:0007275=IEA, GO:0007283=IEA, GO:0003677=IEA, GO:0030154=IEA, GO:0006351=IEA} cell differentiation, multicellular organismal development, oogenesis, regulation of transcription, DNA-dependent, spermatogenesis, transcription, DNA-dependent nucleus DNA binding, protein dimerization activity Human UniProtKB-SubCell:SL-0191 SOLH GOC UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=PMID:9722942, GO:0003700=PMID:9722942, GO:0004198=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0008233=PMID:9722942, GO:0008270=GO_REF:0000002, GO:0008234=PMID:9722942} O75808 Calpain-15 protein 20130413 {GO:0005622=IEA, GO:0006355=TAS, GO:0003700=TAS, GO:0004198=IEA, GO:0006508=IEA, GO:0008233=TAS, GO:0008270=IEA, GO:0008234=TAS} proteolysis, regulation of transcription, DNA-dependent intracellular calcium-dependent cysteine-type endopeptidase activity, cysteine-type peptidase activity, peptidase activity, sequence-specific DNA binding transcription factor activity, zinc ion binding Human SON HPA UniProtKB {GO:0003725=GO_REF:0000002, GO:0008380=GO_REF:0000037, GO:0006397=PMID:21504830, GO:0005515=PMID:21504830, GO:0043066=PMID:10509013, GO:0003723=PMID:21504830, GO:0005730=GO_REF:0000052, GO:0000226=PMID:21504830, GO:0005634=GO_REF:0000052, GO:0050733=GO_REF:0000019, GO:0003676=PMID:1944255, GO:0003677=GO_REF:0000037, GO:0000910=PMID:21504830, GO:0007049=GO_REF:0000037, GO:0016607=PMID:21504830, GO:0051726=PMID:21504830, GO:0043484=PMID:21504830} P18583 Protein SON protein 20101115 {GO:0003725=IEA, GO:0008380=IEA, GO:0006397=IDA, GO:0005515=IPI, GO:0043066=IDA, GO:0003723=IDA, GO:0005730=IDA, GO:0000226=IMP, GO:0005634=IDA, GO:0050733=IEA, GO:0003676=TAS, GO:0003677=IEA, GO:0000910=IMP, GO:0007049=IEA, GO:0016607=IDA, GO:0051726=IMP, GO:0043484=IDA} RNA splicing, cell cycle, cytokinesis, mRNA processing, microtubule cytoskeleton organization, negative regulation of apoptotic process, regulation of RNA splicing, regulation of cell cycle nuclear speck, nucleolus, nucleus DNA binding, RNA binding, RS domain binding, double-stranded RNA binding, nucleic acid binding, protein binding NOT Human SORBS1 HPA UniProtKB {GO:0008286=GO_REF:0000024, GO:0005515=PMID:12504111, GO:0008092=PMID:10085297, GO:0005886=GO_REF:0000052, GO:0005158=PMID:11374898, GO:0043149=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0016363=GO_REF:0000039, GO:0005829=PMID:9447983, GO:0005915=PMID:10085297, GO:0046889=PMID:11001060, GO:0005737=GO_REF:0000052, GO:0005913=GO_REF:0000024, GO:0006936=Reactome:REACT_20558, GO:0015758=GO_REF:0000024, GO:0048041=GO_REF:0000024, GO:0046326=PMID:11001060, GO:0005899=PMID:11374898, GO:0005813=GO_REF:0000052, GO:0001725=GO_REF:0000024, GO:0032869=PMID:11001060, GO:0019901=GO_REF:0000019, GO:0045725=PMID:11001060, GO:0005730=GO_REF:0000052, GO:0003779=PMID:10085297, GO:0007160=PMID:10085297, GO:0005070=PMID:11374898, GO:0045121=GO_REF:0000024, GO:0005924=GO_REF:0000024, GO:0005925=GO_REF:0000052, GO:0090004=GO_REF:0000024} Q9BX66 Sorbin and SH3 domain-containing protein 1 protein 20101115 {GO:0008286=ISS, GO:0005515=IPI, GO:0008092=TAS, GO:0005886=IDA, GO:0005158=IDA, GO:0043149=ISS, GO:0005634=IDA, GO:0016363=IEA, GO:0005829=ISS, GO:0005915=TAS, GO:0046889=ISS, GO:0005737=IDA, GO:0005913=ISS, GO:0006936=TAS, GO:0015758=ISS, GO:0048041=ISS, GO:0046326=ISS, GO:0005899=IDA, GO:0005813=IDA, GO:0001725=ISS, GO:0032869=ISS, GO:0019901=IEA, GO:0045725=ISS, GO:0005730=IDA, GO:0003779=TAS, GO:0007160=TAS, GO:0005070=IC, GO:0045121=ISS, GO:0005924=ISS, GO:0005925=IDA, GO:0090004=ISS} cell-matrix adhesion, cellular response to insulin stimulus, focal adhesion assembly, glucose transport, insulin receptor signaling pathway, muscle contraction, positive regulation of establishment of protein localization to plasma membrane, positive regulation of glucose import, positive regulation of glycogen biosynthetic process, positive regulation of lipid biosynthetic process, stress fiber assembly cell-cell adherens junction, cell-substrate adherens junction, centrosome, cytoplasm, cytosol, focal adhesion, insulin receptor complex, membrane raft, nuclear matrix, nucleolus, nucleus, plasma membrane, stress fiber, zonula adherens SH3/SH2 adaptor activity, actin binding, cytoskeletal protein binding, insulin receptor binding, protein binding, protein kinase binding Human SORBS2 PINC UniProtKB {GO:0008150=GO_REF:0000015, GO:0030018=PMID:9211900, GO:0048471=GO_REF:0000039, GO:0005200=PMID:9211900, GO:0005634=PMID:9211900, GO:0008270=GO_REF:0000002, GO:0015629=PMID:9211900, GO:0008307=PMID:9211900, GO:0008093=PMID:9211900} O94875 Sorbin and SH3 domain-containing protein 2 protein 20030904 {GO:0008150=ND, GO:0030018=NAS, GO:0048471=IEA, GO:0005200=TAS, GO:0005634=NAS, GO:0008270=IEA, GO:0015629=TAS, GO:0008307=TAS, GO:0008093=TAS} biological_process Z disc, actin cytoskeleton, nucleus, perinuclear region of cytoplasm cytoskeletal adaptor activity, structural constituent of cytoskeleton, structural constituent of muscle, zinc ion binding Human SORBS3 Reactome UniProtKB {GO:0031589=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0000122=GO_REF:0000019, GO:0005829=Reactome:REACT_20663, GO:0005737=GO_REF:0000019, GO:0006936=Reactome:REACT_20558, GO:0051495=PMID:9885244, GO:0017166=PMID:9885244, GO:0051496=PMID:9885244, GO:0005200=PMID:9885244, GO:0043410=GO_REF:0000019, GO:0005856=GO_REF:0000039, GO:0007155=PMID:9885244, GO:0005925=PMID:9885244, GO:0008134=GO_REF:0000019} O60504 Vinexin protein 20091105 {GO:0031589=IEA, GO:0005634=IEA, GO:0000122=IEA, GO:0005829=TAS, GO:0005737=IEA, GO:0006936=TAS, GO:0051495=NAS, GO:0017166=IPI, GO:0051496=IDA, GO:0005200=TAS, GO:0043410=IEA, GO:0005856=IEA, GO:0007155=TAS, GO:0005925=IDA, GO:0008134=IEA} cell adhesion, cell-substrate adhesion, muscle contraction, negative regulation of transcription from RNA polymerase II promoter, positive regulation of MAPK cascade, positive regulation of cytoskeleton organization, positive regulation of stress fiber assembly cytoplasm, cytoskeleton, cytosol, focal adhesion, nucleus structural constituent of cytoskeleton, transcription factor binding, vinculin binding Human SORCS1 UniProtKB UniProtKB {GO:0005515=PMID:12482870, GO:0016020=PMID:12482870, GO:0007218=PMID:11499680, GO:0016021=GO_REF:0000037, GO:0008188=PMID:11499680} Q8WY21 VPS10 domain-containing receptor SorCS1 protein 20050708 {GO:0005515=IPI, GO:0016020=IDA, GO:0007218=NAS, GO:0016021=IEA, GO:0008188=NAS} neuropeptide signaling pathway integral to membrane, membrane neuropeptide receptor activity, protein binding Human UniProtKB:Q9BQ90 SORCS3 UniProtKB UniProtKB {GO:0016020=PMID:11499680, GO:0007218=PMID:11499680, GO:0016021=GO_REF:0000037, GO:0008188=PMID:11499680} Q9UPU3 VPS10 domain-containing receptor SorCS3 protein 20030424 {GO:0016020=NAS, GO:0007218=NAS, GO:0016021=IEA, GO:0008188=NAS} neuropeptide signaling pathway integral to membrane, membrane neuropeptide receptor activity Human SORD UniProtKB UniProtKB {GO:0031966=GO_REF:0000039, GO:0031514=GO_REF:0000024, GO:0046370=PMID:3365415, GO:0051160=PMID:8487505, GO:0003939=PMID:3365415, GO:0006062=PMID:3365415, GO:0030317=GO_REF:0000024, GO:0005615=PMID:6177277, GO:0051287=PMID:12962626, GO:0016020=PMID:8487505, GO:0016491=GO_REF:0000038, GO:0051164=PMID:3365415, GO:0006006=PMID:14965227, GO:0030246=PMID:12962626, GO:0008270=PMID:12962626} Q00796 Sorbitol dehydrogenase protein 20110817 {GO:0031966=IEA, GO:0031514=ISS, GO:0046370=IDA, GO:0051160=IDA, GO:0003939=IDA, GO:0006062=IDA, GO:0030317=ISS, GO:0005615=TAS, GO:0051287=IDA, GO:0016020=IDA, GO:0016491=IEA, GO:0051164=IDA, GO:0006006=TAS, GO:0030246=NAS, GO:0008270=IDA} L-xylitol catabolic process, L-xylitol metabolic process, fructose biosynthetic process, glucose metabolic process, sorbitol catabolic process, sperm motility extracellular space, membrane, mitochondrial membrane, motile cilium L-iditol 2-dehydrogenase activity, NAD binding, carbohydrate binding, oxidoreductase activity, zinc ion binding Human UniProtKB:Q64442 SORL1 BHF-UCL UniProtKB {GO:0005887=PMID:9157966, GO:0034362=GO_REF:0000037, GO:0006869=GO_REF:0000037, GO:0030169=PMID:17326667, GO:0006898=PMID:9157966, GO:0004888=PMID:9157966, GO:0008203=GO_REF:0000037} Q92673 Sortilin-related receptor protein 20080111 {GO:0005887=TAS, GO:0034362=IEA, GO:0006869=IEA, GO:0030169=IPI, GO:0006898=TAS, GO:0004888=TAS, GO:0008203=IEA} cholesterol metabolic process, lipid transport, receptor-mediated endocytosis integral to plasma membrane, low-density lipoprotein particle low-density lipoprotein particle binding, transmembrane signaling receptor activity Human UniProtKB:Q6Q788 SORT1 HPA UniProtKB {GO:0010468=PMID:18258592, GO:0048471=PMID:11331584, GO:0005886=PMID:11331584, GO:0030136=PMID:11331584, GO:0010465=PMID:14985763, GO:0048227=PMID:11331584, GO:0005765=GO_REF:0000039, GO:0030425=GO_REF:0000019, GO:0016050=PMID:15992544, GO:0005737=GO_REF:0000052, GO:0030379=PMID:9756851, GO:0007218=PMID:9756851, GO:0046323=PMID:15992544, GO:0032580=GO_REF:0000039, GO:0043025=GO_REF:0000019, GO:0032509=PMID:11331584, GO:0030140=GO_REF:0000019, GO:0032868=PMID:15992544, GO:0031965=GO_REF:0000039, GO:0043066=PMID:14985763, GO:0048011=PMID:14985763, GO:0014902=PMID:18258592, GO:0005794=PMID:11331584, GO:0009986=PMID:10085125, GO:0048406=PMID:14985763, GO:0008333=PMID:11331584, GO:0006895=PMID:11331584, GO:0097190=PMID:14985763, GO:0006897=PMID:11331584, GO:0051005=PMID:10085125, GO:0005905=PMID:11331584, GO:0007186=PMID:18258592, GO:0001503=GO_REF:0000037, GO:0005789=GO_REF:0000039, GO:0016023=PMID:9756851, GO:0016021=PMID:15992544, GO:0019899=PMID:10085125, GO:0005769=PMID:11331584, GO:0010008=GO_REF:0000039, GO:0005768=GO_REF:0000029} Q99523 Sortilin protein 20120912 {GO:0010468=IMP, GO:0048471=IDA, GO:0005886=IDA, GO:0030136=IDA, GO:0010465=IDA, GO:0048227=IDA, GO:0005765=IEA, GO:0030425=IEA, GO:0016050=IDA, GO:0005737=IDA, GO:0030379=IDA, GO:0007218=IDA, GO:0046323=IMP, GO:0032580=IEA, GO:0043025=IEA, GO:0032509=IDA, GO:0030140=IEA, GO:0032868=IMP, GO:0031965=IEA, GO:0043066=IDA, GO:0048011=IMP, GO:0014902=IMP, GO:0005794=IDA, GO:0009986=IDA, GO:0048406=IPI, GO:0008333=IDA, GO:0006895=IDA, GO:0097190=IMP, GO:0006897=IDA, GO:0051005=IDA, GO:0005905=IDA, GO:0007186=IMP, GO:0001503=IEA, GO:0005789=IEA, GO:0016023=IDA, GO:0016021=IDA, GO:0019899=IPI, GO:0005769=IDA, GO:0010008=IEA, GO:0005768=NAS} G-protein coupled receptor signaling pathway, Golgi to endosome transport, apoptotic signaling pathway, endocytosis, endosome to lysosome transport, endosome transport via multivesicular body sorting pathway, glucose import, myotube differentiation, negative regulation of apoptotic process, negative regulation of lipoprotein lipase activity, neuropeptide signaling pathway, neurotrophin TRK receptor signaling pathway, ossification, plasma membrane to endosome transport, regulation of gene expression, response to insulin stimulus, vesicle organization Golgi apparatus, Golgi cisterna membrane, cell surface, clathrin-coated vesicle, coated pit, cytoplasm, cytoplasmic membrane-bounded vesicle, dendrite, early endosome, endoplasmic reticulum membrane, endosome, endosome membrane, integral to membrane, lysosomal membrane, neuronal cell body, nuclear membrane, perinuclear region of cytoplasm, plasma membrane, trans-Golgi network transport vesicle enzyme binding, nerve growth factor binding, nerve growth factor receptor activity, neurotensin receptor activity, non-G-protein coupled Human SOS1 GOC UniProtKB {GO:0005515=PMID:21988832, GO:0008286=Reactome:REACT_498, GO:0005886=Reactome:REACT_118834, GO:0035023=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0007265=Reactome:REACT_12033, GO:0050900=Reactome:REACT_12051, GO:0005829=Reactome:REACT_147838, GO:0005622=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0007173=Reactome:REACT_9417, GO:0007411=Reactome:REACT_18266, GO:0005089=GO_REF:0000002, GO:0005088=Reactome:REACT_18366, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0046982=GO_REF:0000002, GO:0006915=Reactome:REACT_13638, GO:0030168=Reactome:REACT_798, GO:0097190=Reactome:REACT_13720, GO:0003677=GO_REF:0000002, GO:0005100=PMID:9790532, GO:0007165=PMID:8493579, GO:0007596=Reactome:REACT_604, GO:0008543=Reactome:REACT_9470, GO:0032321=PMID:9790532, GO:0045087=Reactome:REACT_6802} Q07889 Son of sevenless homolog 1 protein 20130413 {GO:0005515=IPI, GO:0008286=TAS, GO:0005886=TAS, GO:0035023=IEA, GO:0007264=TAS, GO:0007265=TAS, GO:0050900=TAS, GO:0005829=TAS, GO:0005622=IEA, GO:0005543=IEA, GO:0007173=TAS, GO:0007411=TAS, GO:0005089=IEA, GO:0005088=TAS, GO:0051056=TAS, GO:0048011=TAS, GO:0046982=IEA, GO:0006915=TAS, GO:0030168=TAS, GO:0097190=TAS, GO:0003677=IEA, GO:0005100=TAS, GO:0007165=NAS, GO:0007596=TAS, GO:0008543=TAS, GO:0032321=TAS, GO:0045087=TAS} Ras protein signal transduction, apoptotic process, apoptotic signaling pathway, axon guidance, blood coagulation, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, leukocyte migration, neurotrophin TRK receptor signaling pathway, platelet activation, positive regulation of Rho GTPase activity, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular, plasma membrane DNA binding, Ras guanyl-nucleotide exchange factor activity, Rho GTPase activator activity, Rho guanyl-nucleotide exchange factor activity, phospholipid binding, protein binding, protein heterodimerization activity Human SOS2 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0046982=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0035023=GO_REF:0000002, GO:0006915=Reactome:REACT_13638, GO:0097190=Reactome:REACT_13720, GO:0003677=GO_REF:0000002, GO:0005829=Reactome:REACT_19216, GO:0005622=GO_REF:0000002, GO:0005085=GO_REF:0000029, GO:0005543=GO_REF:0000002, GO:0007411=Reactome:REACT_18266, GO:0005089=GO_REF:0000002} Q07890 Son of sevenless homolog 2 protein 20130415 {GO:0005515=IPI, GO:0051056=TAS, GO:0048011=TAS, GO:0046982=IEA, GO:0007264=TAS, GO:0035023=IEA, GO:0006915=TAS, GO:0097190=TAS, GO:0003677=IEA, GO:0005829=TAS, GO:0005622=IEA, GO:0005085=NAS, GO:0005543=IEA, GO:0007411=TAS, GO:0005089=IEA} apoptotic process, apoptotic signaling pathway, axon guidance, neurotrophin TRK receptor signaling pathway, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol, intracellular DNA binding, Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, phospholipid binding, protein binding, protein heterodimerization activity Human UniProtKB:P62993 SOSTDC1 ENSEMBL UniProtKB {GO:0030514=GO_REF:0000019, GO:0007389=GO_REF:0000019, GO:0042475=GO_REF:0000019, GO:0016055=GO_REF:0000037, GO:0005615=GO_REF:0000019} Q6X4U4 Sclerostin domain-containing protein 1 protein 20130413 {GO:0030514=IEA, GO:0007389=IEA, GO:0042475=IEA, GO:0016055=IEA, GO:0005615=IEA} Wnt receptor signaling pathway, negative regulation of BMP signaling pathway, odontogenesis of dentin-containing tooth, pattern specification process extracellular space Human Ensembl:ENSMUSP00000040230 SOX1 UniProtKB UniProtKB {GO:0006355=PMID:9337405, GO:0003700=PMID:9337405, GO:0021521=GO_REF:0000019, GO:0002089=GO_REF:0000019, GO:0006325=PMID:9337405, GO:0005634=PMID:9337405, GO:0001046=PMID:20049565, GO:0021884=GO_REF:0000019, GO:0001764=GO_REF:0000019, GO:0003677=PMID:9337405, GO:0006351=GO_REF:0000037} O00570 Transcription factor SOX-1 protein 20010831 {GO:0006355=NAS, GO:0003700=NAS, GO:0021521=IEA, GO:0002089=IEA, GO:0006325=NAS, GO:0005634=NAS, GO:0001046=IDA, GO:0021884=IEA, GO:0001764=IEA, GO:0003677=NAS, GO:0006351=IEA} chromatin organization, forebrain neuron development, lens morphogenesis in camera-type eye, neuron migration, regulation of transcription, DNA-dependent, transcription, DNA-dependent, ventral spinal cord interneuron specification nucleus DNA binding, core promoter sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human SOX10 IntAct UniProtKB {GO:0005515=PMID:16214168, GO:0048709=GO_REF:0000019, GO:0003705=GO_REF:0000019, GO:0001755=GO_REF:0000019, GO:0005634=PMID:18512230, GO:0009653=PMID:9425902, GO:0042802=PMID:11029584, GO:0048589=GO_REF:0000019, GO:0031315=GO_REF:0000019, GO:0014015=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0048469=GO_REF:0000019, GO:0090090=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0006357=PMID:9722528, GO:0003713=PMID:9722528, GO:0002052=GO_REF:0000019, GO:0030318=GO_REF:0000019, GO:0000978=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0048546=GO_REF:0000019, GO:0048484=GO_REF:0000019, GO:0048863=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0007422=GO_REF:0000019, GO:0000980=GO_REF:0000019, GO:0045892=GO_REF:0000019, GO:0008134=GO_REF:0000019} P56693 Transcription factor SOX-10 protein 20130415 {GO:0005515=IPI, GO:0048709=IEA, GO:0003705=IEA, GO:0001755=IEA, GO:0005634=IDA, GO:0009653=TAS, GO:0042802=IPI, GO:0048589=IEA, GO:0031315=IEA, GO:0014015=IEA, GO:0045944=IEA, GO:0048469=IEA, GO:0090090=IEA, GO:0043066=IEA, GO:0006357=TAS, GO:0003713=TAS, GO:0002052=IEA, GO:0030318=IEA, GO:0000978=IEA, GO:0001701=IEA, GO:0048546=IEA, GO:0048484=IEA, GO:0048863=IEA, GO:0003682=IEA, GO:0007422=IEA, GO:0000980=IEA, GO:0045892=IEA, GO:0008134=IEA} anatomical structure morphogenesis, cell maturation, developmental growth, digestive tract morphogenesis, enteric nervous system development, in utero embryonic development, melanocyte differentiation, negative regulation of apoptotic process, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of transcription, DNA-dependent, neural crest cell migration, oligodendrocyte differentiation, peripheral nervous system development, positive regulation of gliogenesis, positive regulation of neuroblast proliferation, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, stem cell differentiation extrinsic to mitochondrial outer membrane, nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, chromatin binding, identical protein binding, protein binding, transcription coactivator activity, transcription factor binding Human UniProtKB:P56693 SOX11 GOC UniProtKB {GO:0048704=GO_REF:0000024, GO:2001111=GO_REF:0000024, GO:0006412=PMID:10606637, GO:0014032=GO_REF:0000024, GO:0046887=GO_REF:0000024, GO:0060548=GO_REF:0000024, GO:0017015=PMID:20624318, GO:0001105=GO_REF:0000024, GO:0000976=GO_REF:0000024, GO:0000122=PMID:19808959, GO:0048485=GO_REF:0000024, GO:0001841=GO_REF:0000024, GO:0050672=PMID:20624318, GO:0035332=GO_REF:0000024, GO:0001501=GO_REF:0000024, GO:0061053=GO_REF:0000024, GO:0021782=GO_REF:0000024, GO:0060174=GO_REF:0000024, GO:0045893=GO_REF:0000024, GO:0003357=GO_REF:0000024, GO:0001158=PMID:19808959, GO:0008135=PMID:10606637, GO:0008284=GO_REF:0000024, GO:0021510=GO_REF:0000024, GO:0060425=GO_REF:0000024, GO:0005634=PMID:17934069, GO:2000678=GO_REF:0000024, GO:0045778=PMID:20626275, GO:0014009=GO_REF:0000024, GO:0030513=GO_REF:0000024, GO:0005737=PMID:17934069, GO:0002089=GO_REF:0000024, GO:0050769=GO_REF:0000024, GO:0061029=GO_REF:0000024, GO:0030182=PMID:10574465, GO:0060022=GO_REF:0000024, GO:0060023=GO_REF:0000024, GO:0001822=GO_REF:0000019, GO:0060412=GO_REF:0000024, GO:0060563=GO_REF:0000024, GO:2000648=PMID:20626275, GO:0072395=PMID:20624318, GO:0060253=PMID:19808959, GO:0003151=GO_REF:0000024, GO:0061386=GO_REF:0000024, GO:0045669=PMID:20626275, GO:0010628=PMID:19808959, GO:0061303=GO_REF:0000024, GO:0001077=GO_REF:0000024, GO:0048557=GO_REF:0000024, GO:0003211=GO_REF:0000024, GO:0045666=PMID:19808959, GO:0014003=GO_REF:0000019, GO:0010629=PMID:19808959, GO:0001071=GO_REF:0000024} P35716 Transcription factor SOX-11 protein 20130413 {GO:0048704=ISS, GO:2001111=ISS, GO:0006412=IDA, GO:0014032=ISS, GO:0046887=ISS, GO:0060548=ISS, GO:0017015=IEP, GO:0001105=ISS, GO:0000976=ISS, GO:0000122=IDA, GO:0048485=ISS, GO:0001841=ISS, GO:0050672=IMP, GO:0035332=ISS, GO:0001501=ISS, GO:0061053=ISS, GO:0021782=ISS, GO:0060174=ISS, GO:0045893=ISS, GO:0003357=ISS, GO:0001158=IDA, GO:0008135=IDA, GO:0008284=ISS, GO:0021510=ISS, GO:0060425=ISS, GO:0005634=IDA, GO:2000678=ISS, GO:0045778=IMP, GO:0014009=ISS, GO:0030513=ISS, GO:0005737=IDA, GO:0002089=ISS, GO:0050769=ISS, GO:0061029=ISS, GO:0030182=IEP, GO:0060022=ISS, GO:0060023=ISS, GO:0001822=IEA, GO:0060412=ISS, GO:0060563=ISS, GO:2000648=IMP, GO:0072395=IEP, GO:0060253=IMP, GO:0003151=ISS, GO:0061386=ISS, GO:0045669=IMP, GO:0010628=IMP, GO:0061303=ISS, GO:0001077=ISS, GO:0048557=ISS, GO:0003211=ISS, GO:0045666=IMP, GO:0014003=IEA, GO:0010629=IMP, GO:0001071=ISS} cardiac ventricle formation, closure of optic fissure, cornea development in camera-type eye, embryonic digestive tract morphogenesis, embryonic skeletal system morphogenesis, eyelid development in camera-type eye, glial cell development, glial cell proliferation, hard palate development, kidney development, lens morphogenesis in camera-type eye, limb bud formation, lung morphogenesis, negative regulation of cell death, negative regulation of gene expression, negative regulation of glial cell proliferation, negative regulation of lymphocyte proliferation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription regulatory region DNA binding, neural crest cell development, neural tube formation, neuroepithelial cell differentiation, neuron differentiation, noradrenergic neuron differentiation, oligodendrocyte development, outflow tract morphogenesis, positive regulation of BMP signaling pathway, positive regulation of cell proliferation, positive regulation of gene expression, positive regulation of hippo signaling cascade, positive regulation of hormone secretion, positive regulation of lens epithelial cell proliferation, positive regulation of neurogenesis, positive regulation of neuron differentiation, positive regulation of ossification, positive regulation of osteoblast differentiation, positive regulation of stem cell proliferation, positive regulation of transcription, DNA-dependent, regulation of transforming growth factor beta receptor signaling pathway, signal transduction involved in cell cycle checkpoint, skeletal system development, soft palate development, somite development, spinal cord development, sympathetic nervous system development, translation, ventricular septum morphogenesis cytoplasm, nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II transcription coactivator activity, enhancer sequence-specific DNA binding, nucleic acid binding transcription factor activity, transcription regulatory region sequence-specific DNA binding, translation factor activity, nucleic acid binding Human SOX12 UniProtKB UniProtKB {GO:0001077=GO_REF:0000024, GO:0001105=GO_REF:0000024, GO:0000976=GO_REF:0000024, GO:0045165=PMID:9215677, GO:0021510=GO_REF:0000024, GO:0006357=PMID:9215677, GO:0032993=GO_REF:0000019, GO:0045944=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0003677=PMID:9215677, GO:0065004=GO_REF:0000019} O15370 Transcription factor SOX-12 protein 20110624 {GO:0001077=ISS, GO:0001105=ISS, GO:0000976=ISS, GO:0045165=IEP, GO:0021510=ISS, GO:0006357=NAS, GO:0032993=IEA, GO:0045944=ISS, GO:0005634=IEA, GO:0005575=ND, GO:0003677=NAS, GO:0065004=IEA} cell fate commitment, positive regulation of transcription from RNA polymerase II promoter, protein-DNA complex assembly, regulation of transcription from RNA polymerase II promoter, spinal cord development cellular_component, nucleus, protein-DNA complex DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II transcription coactivator activity, transcription regulatory region sequence-specific DNA binding Human UniProtKB:Q04890 SOX13 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0043565=GO_REF:0000024, GO:0003700=PMID:10198172, GO:0005634=GO_REF:0000024, GO:0009653=PMID:10198172, GO:0006351=GO_REF:0000037} Q9UN79 Transcription factor SOX-13 protein 20130415 {GO:0005515=IPI, GO:0043565=ISS, GO:0003700=TAS, GO:0005634=ISS, GO:0009653=TAS, GO:0006351=IEA} anatomical structure morphogenesis, transcription, DNA-dependent nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:P56545 SOX15 BHF-UCL UniProtKB {GO:0006355=PMID:8332506, GO:0003700=PMID:8332506, GO:0006357=PMID:9540826, GO:0014718=PMID:17363903, GO:0006325=PMID:8332506, GO:0070318=PMID:17363903, GO:0005634=PMID:8332506, GO:0000122=PMID:17363903, GO:0003677=PMID:8332506, GO:0045843=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0045944=PMID:17363903, GO:0048627=GO_REF:0000019, GO:0043403=GO_REF:0000019, GO:2000288=PMID:17363903, GO:0008584=PMID:9540826} O60248 Protein SOX-15 protein 20121126 {GO:0006355=NAS, GO:0003700=NAS, GO:0006357=TAS, GO:0014718=ISS, GO:0006325=NAS, GO:0070318=ISS, GO:0005634=NAS, GO:0000122=ISS, GO:0003677=NAS, GO:0045843=IEA, GO:0005737=IEA, GO:0003682=IEA, GO:0045944=ISS, GO:0048627=IEA, GO:0043403=IEA, GO:2000288=ISS, GO:0008584=TAS} chromatin organization, male gonad development, myoblast development, negative regulation of striated muscle tissue development, negative regulation of transcription from RNA polymerase II promoter, positive regulation of G0 to G1 transition, positive regulation of myoblast proliferation, positive regulation of satellite cell activation involved in skeletal muscle regeneration, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, skeletal muscle tissue regeneration cytoplasm, nucleus DNA binding, chromatin binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:P43267 SOX17 BHF-UCL UniProtKB {GO:0030308=PMID:18413743, GO:0008013=PMID:17875931, GO:0044212=GO_REF:0000024, GO:0003705=GO_REF:0000024, GO:0045597=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0060913=PMID:19736317, GO:0001947=GO_REF:0000024, GO:0003308=GO_REF:0000019, GO:0003143=GO_REF:0000024, GO:0003142=GO_REF:0000024, GO:0042074=GO_REF:0000019, GO:0060914=PMID:19736317, GO:0061009=GO_REF:0000019, GO:0060956=GO_REF:0000024, GO:0042789=PMID:22292085, GO:0001706=PMID:18682240, GO:0023019=GO_REF:0000019, GO:0003713=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0048643=GO_REF:0000019, GO:2000035=GO_REF:0000019, GO:2000043=GO_REF:0000019, GO:0072091=GO_REF:0000019, GO:0061010=GO_REF:0000019, GO:0072001=PMID:20960469, GO:0045893=GO_REF:0000024, GO:0008134=PMID:17875931, GO:0045732=GO_REF:0000019, GO:0042662=GO_REF:0000019, GO:0005634=PMID:17875931, GO:0048866=GO_REF:0000019, GO:0031648=PMID:17875931, GO:0048568=GO_REF:0000019, GO:0045944=PMID:22292085, GO:0090090=PMID:18413743, GO:0021903=GO_REF:0000019, GO:0060070=GO_REF:0000019, GO:0005667=PMID:19736317, GO:0006355=GO_REF:0000024, GO:0035050=GO_REF:0000024, GO:0050821=PMID:17875931, GO:0060214=GO_REF:0000024, GO:0060807=GO_REF:0000024, GO:0001525=GO_REF:0000024, GO:0001828=GO_REF:0000019, GO:0003151=GO_REF:0000024, GO:0043565=GO_REF:0000019, GO:0045995=GO_REF:0000024, GO:0007493=GO_REF:0000019, GO:0048617=GO_REF:0000024, GO:0001570=GO_REF:0000024, GO:0061031=GO_REF:0000024} Q9H6I2 Transcription factor SOX-17 protein 20100317 {GO:0030308=IMP, GO:0008013=IPI, GO:0044212=ISS, GO:0003705=ISS, GO:0045597=IEA, GO:0007283=IEA, GO:0060913=IMP, GO:0001947=ISS, GO:0003308=IEA, GO:0003143=ISS, GO:0003142=ISS, GO:0042074=IEA, GO:0060914=TAS, GO:0061009=IEA, GO:0060956=ISS, GO:0042789=IDA, GO:0001706=IDA, GO:0023019=IEA, GO:0003713=IEA, GO:0000122=IEA, GO:0048643=IEA, GO:2000035=IEA, GO:2000043=IEA, GO:0072091=IEA, GO:0061010=IEA, GO:0072001=IMP, GO:0045893=ISS, GO:0008134=IPI, GO:0045732=IEA, GO:0042662=IEA, GO:0005634=IDA, GO:0048866=IEA, GO:0031648=IMP, GO:0048568=IEA, GO:0045944=IDA, GO:0090090=IMP, GO:0021903=IEA, GO:0060070=IEA, GO:0005667=IDA, GO:0006355=ISS, GO:0035050=ISS, GO:0050821=IMP, GO:0060214=ISS, GO:0060807=ISS, GO:0001525=ISS, GO:0001828=IEA, GO:0003151=ISS, GO:0043565=IEA, GO:0045995=ISS, GO:0007493=IEA, GO:0048617=ISS, GO:0001570=ISS, GO:0061031=ISS} angiogenesis, canonical Wnt receptor signaling pathway, cardiac cell fate determination, cardiogenic plate morphogenesis, cell migration involved in gastrulation, common bile duct development, embryonic foregut morphogenesis, embryonic heart tube development, embryonic heart tube morphogenesis, embryonic organ development, endocardial cell differentiation, endocardium formation, endoderm formation, endodermal cell fate determination, endodermal digestive tract morphogenesis, gall bladder development, heart formation, heart looping, inner cell mass cellular morphogenesis, mRNA transcription from RNA polymerase II promoter, negative regulation of Wnt receptor signaling pathway involved in heart development, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cell growth, negative regulation of mesodermal cell fate specification, negative regulation of transcription from RNA polymerase II promoter, outflow tract morphogenesis, positive regulation of cell differentiation, positive regulation of protein catabolic process, positive regulation of skeletal muscle tissue development, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein destabilization, protein stabilization, regulation of cardiac cell fate specification, regulation of embryonic development, regulation of stem cell division, regulation of stem cell proliferation, regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification, regulation of transcription, DNA-dependent, renal system development, rostrocaudal neural tube patterning, signal transduction involved in regulation of gene expression, spermatogenesis, stem cell fate specification, vasculogenesis nucleus, transcription factor complex RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, beta-catenin binding, sequence-specific DNA binding, transcription coactivator activity, transcription factor binding, transcription regulatory region DNA binding Human UniProtKB:Q61473 SOX18 BHF-UCL UniProtKB {GO:0000790=PMID:22292085, GO:0044212=PMID:18065521, GO:0060836=GO_REF:0000024, GO:0048866=GO_REF:0000019, GO:0001947=GO_REF:0000024, GO:0001946=PMID:12740761, GO:0061028=PMID:18065521, GO:0045944=PMID:22292085, GO:0060956=GO_REF:0000024, GO:0048469=GO_REF:0000019, GO:0042789=PMID:22292085, GO:0001942=GO_REF:0000019, GO:0001944=GO_REF:0000024, GO:0035050=GO_REF:0000024, GO:0060214=GO_REF:0000024, GO:0000122=PMID:22292085, GO:0001525=PMID:16882943, GO:0000978=PMID:22292085, GO:0001701=GO_REF:0000019, GO:0003151=GO_REF:0000024, GO:0022405=PMID:12740761, GO:0001077=PMID:22292085, GO:0043534=PMID:16882943, GO:0072091=GO_REF:0000019, GO:0045893=GO_REF:0000024, GO:0001570=GO_REF:0000024, GO:0045892=GO_REF:0000024} P35713 Transcription factor SOX-18 protein 20100317 {GO:0000790=IDA, GO:0044212=IDA, GO:0060836=ISS, GO:0048866=IEA, GO:0001947=ISS, GO:0001946=IMP, GO:0061028=IMP, GO:0045944=IDA, GO:0060956=ISS, GO:0048469=IEA, GO:0042789=IDA, GO:0001942=IEA, GO:0001944=ISS, GO:0035050=ISS, GO:0060214=ISS, GO:0000122=IDA, GO:0001525=IEP, GO:0000978=IDA, GO:0001701=IEA, GO:0003151=ISS, GO:0022405=IMP, GO:0001077=IDA, GO:0043534=IEP, GO:0072091=IEA, GO:0045893=ISS, GO:0001570=ISS, GO:0045892=ISS} angiogenesis, blood vessel endothelial cell migration, cell maturation, embryonic heart tube development, endocardial cell differentiation, endocardium formation, establishment of endothelial barrier, hair cycle process, hair follicle development, heart looping, in utero embryonic development, lymphangiogenesis, lymphatic endothelial cell differentiation, mRNA transcription from RNA polymerase II promoter, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, outflow tract morphogenesis, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of stem cell proliferation, stem cell fate specification, vasculature development, vasculogenesis nuclear chromatin RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, transcription regulatory region DNA binding Human UniProtKB:P43680 SOX2 BHF-UCL UniProtKB {GO:0010468=PMID:18388306, GO:0005515=PMID:18456656, GO:0003700=PMID:16153702, GO:0044212=PMID:18407919, GO:0001654=PMID:18285410, GO:0060042=GO_REF:0000019, GO:0006325=PMID:7849401, GO:0050680=PMID:18268498, GO:0001714=PMID:21245162, GO:0030539=GO_REF:0000019, GO:0048852=GO_REF:0000019, GO:0045747=GO_REF:0000019, GO:0030910=GO_REF:0000019, GO:0048839=PMID:18407919, GO:0000976=GO_REF:0000019, GO:0042472=GO_REF:0000019, GO:0060235=GO_REF:0000019, GO:0048286=GO_REF:0000019, GO:0021879=GO_REF:0000019, GO:0000122=GO_REF:0000024, GO:0070848=PMID:18187129, GO:0001649=PMID:18187129, GO:0060441=GO_REF:0000019, GO:0043281=PMID:18268498, GO:0050973=GO_REF:0000019, GO:0043586=GO_REF:0000019, GO:0045893=PMID:18407919, GO:0021984=GO_REF:0000019, GO:0021987=GO_REF:0000019, GO:0021983=PMID:18285410, GO:0005634=PMID:16153702, GO:0021781=PMID:17291498, GO:0005829=PMID:18000303, GO:0030858=GO_REF:0000019, GO:0005737=PMID:18027866, GO:0045944=PMID:21245162, GO:0007050=PMID:18268498, GO:0032526=GO_REF:0000019, GO:0035019=PMID:19736317, GO:0090090=PMID:18285410, GO:0097150=GO_REF:0000024, GO:0005667=PMID:19736317, GO:0006355=PMID:16153702, GO:0009611=PMID:17982423, GO:0002052=GO_REF:0000019, GO:0048663=GO_REF:0000019, GO:0003677=PMID:16153702, GO:0043565=PMID:20713518, GO:0001077=GO_REF:0000019, GO:0045668=GO_REF:0000019, GO:0035198=PMID:18710938, GO:0045665=GO_REF:0000024, GO:0045666=GO_REF:0000019, GO:0050910=GO_REF:0000019, GO:0046148=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0030900=PMID:18285410, GO:0043410=PMID:18187129} P48431 Transcription factor SOX-2 protein 20100324 {GO:0010468=IMP, GO:0005515=IPI, GO:0003700=IDA, GO:0044212=IDA, GO:0001654=IEP, GO:0060042=IEA, GO:0006325=NAS, GO:0050680=IDA, GO:0001714=IDA, GO:0030539=IEA, GO:0048852=IEA, GO:0045747=IEA, GO:0030910=IEA, GO:0048839=IEP, GO:0000976=IEA, GO:0042472=IEA, GO:0060235=IEA, GO:0048286=IEA, GO:0021879=IEA, GO:0000122=ISS, GO:0070848=IDA, GO:0001649=IDA, GO:0060441=IEA, GO:0043281=IDA, GO:0050973=IEA, GO:0043586=IEA, GO:0045893=IDA, GO:0021984=IEA, GO:0021987=IEA, GO:0021983=IEP, GO:0005634=IC, GO:0021781=NAS, GO:0005829=IDA, GO:0030858=IEA, GO:0005737=IDA, GO:0045944=IDA, GO:0007050=IDA, GO:0032526=IEA, GO:0035019=IMP, GO:0090090=IDA, GO:0097150=ISS, GO:0005667=TAS, GO:0006355=IDA, GO:0009611=IEP, GO:0002052=IEA, GO:0048663=IEA, GO:0003677=IDA, GO:0043565=IDA, GO:0001077=IEA, GO:0045668=IEA, GO:0035198=IDA, GO:0045665=ISS, GO:0045666=IEA, GO:0050910=IEA, GO:0046148=IEA, GO:0003682=IEA, GO:0030900=IEP, GO:0043410=IDA} adenohypophysis development, cell cycle arrest, cerebral cortex development, chromatin organization, detection of mechanical stimulus involved in equilibrioception, detection of mechanical stimulus involved in sensory perception of sound, diencephalon morphogenesis, endodermal cell fate specification, epithelial tube branching involved in lung morphogenesis, eye development, forebrain development, forebrain neuron differentiation, glial cell fate commitment, inner ear development, inner ear morphogenesis, lens induction in camera-type eye, lung alveolus development, male genitalia development, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of epithelial cell proliferation, negative regulation of neuron differentiation, negative regulation of osteoblast differentiation, negative regulation of transcription from RNA polymerase II promoter, neuron fate commitment, neuronal stem cell maintenance, olfactory placode formation, osteoblast differentiation, pigment biosynthetic process, pituitary gland development, positive regulation of MAPK cascade, positive regulation of Notch signaling pathway, positive regulation of epithelial cell differentiation, positive regulation of neuroblast proliferation, positive regulation of neuron differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of cysteine-type endopeptidase activity involved in apoptotic process, regulation of gene expression, regulation of transcription, DNA-dependent, response to growth factor stimulus, response to retinoic acid, response to wounding, retina morphogenesis in camera-type eye, somatic stem cell maintenance, tongue development cytoplasm, cytosol, nucleus, transcription factor complex DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, chromatin binding, miRNA binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding, transcription regulatory region sequence-specific DNA binding Human SOX3 PINC UniProtKB {GO:0001106=GO_REF:0000024, GO:0021983=GO_REF:0000024, GO:0048515=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0007417=PMID:8625802, GO:0021854=GO_REF:0000024, GO:0000979=GO_REF:0000024, GO:0003677=PMID:8625802, GO:0007530=PMID:21183788, GO:0007423=GO_REF:0000024, GO:0060009=GO_REF:0000019, GO:0045665=GO_REF:0000024, GO:0060324=GO_REF:0000024, GO:0009887=GO_REF:0000019} P41225 Transcription factor SOX-3 protein 20030904 {GO:0001106=ISS, GO:0021983=ISS, GO:0048515=IEA, GO:0005634=IEA, GO:0007417=TAS, GO:0021854=ISS, GO:0000979=ISS, GO:0003677=TAS, GO:0007530=IMP, GO:0007423=ISS, GO:0060009=IEA, GO:0045665=ISS, GO:0060324=ISS, GO:0009887=IEA} Sertoli cell development, central nervous system development, face development, hypothalamus development, negative regulation of neuron differentiation, organ morphogenesis, pituitary gland development, sensory organ development, sex determination, spermatid differentiation nucleus DNA binding, RNA polymerase II core promoter sequence-specific DNA binding, RNA polymerase II transcription corepressor activity Human SOX30 UniProtKB UniProtKB {GO:0043565=PMID:10359848, GO:0006355=GO_REF:0000037, GO:0031960=PMID:18436822, GO:0005634=GO_REF:0000039, GO:0007283=GO_REF:0000019, GO:0006351=GO_REF:0000037} O94993 Transcription factor SOX-30 protein 20110107 {GO:0043565=IDA, GO:0006355=IEA, GO:0031960=IEP, GO:0005634=IEA, GO:0007283=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, response to corticosteroid stimulus, spermatogenesis, transcription, DNA-dependent nucleus sequence-specific DNA binding Human SOX4 HPA UniProtKB {GO:0005515=PMID:16631117, GO:0003289=GO_REF:0000024, GO:0003700=PMID:16631117, GO:0090263=GO_REF:0000024, GO:0003183=GO_REF:0000024, GO:0007507=GO_REF:0000024, GO:0060993=GO_REF:0000024, GO:0060548=GO_REF:0000024, GO:0032024=GO_REF:0000024, GO:0002328=GO_REF:0000024, GO:0031397=PMID:19234109, GO:0006977=PMID:19234109, GO:0000976=GO_REF:0000024, GO:0001105=GO_REF:0000024, GO:0048485=GO_REF:0000024, GO:0001841=GO_REF:0000024, GO:0001501=GO_REF:0000024, GO:0021782=GO_REF:0000024, GO:0060174=GO_REF:0000024, GO:2000761=PMID:19234109, GO:0045893=PMID:16631117, GO:0003357=GO_REF:0000024, GO:0035910=GO_REF:0000024, GO:0008284=PMID:17875931, GO:0008285=PMID:19234109, GO:0021510=GO_REF:0000024, GO:0030177=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0003215=GO_REF:0000024, GO:0014009=GO_REF:0000024, GO:0005739=GO_REF:0000052, GO:0046826=PMID:19234109, GO:0005737=PMID:17875931, GO:0031647=PMID:19234109, GO:0042769=PMID:19234109, GO:0045944=PMID:19147588, GO:0001046=PMID:20049565, GO:0071333=GO_REF:0000024, GO:0060070=GO_REF:0000024, GO:0035019=GO_REF:0000019, GO:0043066=PMID:16636670, GO:0006355=PMID:16631117, GO:0043065=PMID:15522200, GO:0021522=GO_REF:0000024, GO:0060412=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0050821=PMID:17875931, GO:0060563=GO_REF:0000024, GO:0045727=PMID:19234109, GO:0042593=GO_REF:0000024, GO:0001077=PMID:19147588, GO:0030217=GO_REF:0000024, GO:0003211=GO_REF:0000024, GO:0031018=GO_REF:0000019, GO:0001071=PMID:20049565} Q06945 Transcription factor SOX-4 protein 20101115 {GO:0005515=IPI, GO:0003289=ISS, GO:0003700=IDA, GO:0090263=ISS, GO:0003183=ISS, GO:0007507=ISS, GO:0060993=ISS, GO:0060548=ISS, GO:0032024=ISS, GO:0002328=ISS, GO:0031397=IMP, GO:0006977=IMP, GO:0000976=ISS, GO:0001105=ISS, GO:0048485=ISS, GO:0001841=ISS, GO:0001501=ISS, GO:0021782=ISS, GO:0060174=ISS, GO:2000761=IDA, GO:0045893=IDA, GO:0003357=ISS, GO:0035910=ISS, GO:0008284=IMP, GO:0008285=IMP, GO:0021510=ISS, GO:0030177=ISS, GO:0005634=IDA, GO:0003215=ISS, GO:0014009=ISS, GO:0005739=IDA, GO:0046826=IMP, GO:0005737=IDA, GO:0031647=IMP, GO:0042769=IDA, GO:0045944=IDA, GO:0001046=IDA, GO:0071333=ISS, GO:0060070=ISS, GO:0035019=IEA, GO:0043066=IMP, GO:0006355=IDA, GO:0043065=IMP, GO:0021522=ISS, GO:0060412=ISS, GO:0005730=IDA, GO:0050821=IMP, GO:0060563=ISS, GO:0045727=IMP, GO:0042593=ISS, GO:0001077=IDA, GO:0030217=ISS, GO:0003211=ISS, GO:0031018=IEA, GO:0001071=IMP} DNA damage response, detection of DNA damage, DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, T cell differentiation, ascending aorta morphogenesis, atrial septum primum morphogenesis, canonical Wnt receptor signaling pathway, cardiac right ventricle morphogenesis, cardiac ventricle formation, cellular response to glucose stimulus, endocrine pancreas development, glial cell development, glial cell proliferation, glucose homeostasis, heart development, kidney morphogenesis, limb bud formation, mitral valve morphogenesis, negative regulation of apoptotic process, negative regulation of cell death, negative regulation of cell proliferation, negative regulation of protein export from nucleus, negative regulation of protein ubiquitination, neural tube formation, neuroepithelial cell differentiation, noradrenergic neuron differentiation, positive regulation of N-terminal peptidyl-lysine acetylation, positive regulation of Wnt receptor signaling pathway, positive regulation of apoptotic process, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of cell proliferation, positive regulation of insulin secretion, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of translation, pro-B cell differentiation, protein stabilization, regulation of protein stability, regulation of transcription, DNA-dependent, skeletal system development, somatic stem cell maintenance, spinal cord development, spinal cord motor neuron differentiation, sympathetic nervous system development, ventricular septum morphogenesis cytoplasm, mitochondrion, nucleolus, nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II transcription coactivator activity, core promoter sequence-specific DNA binding, nucleic acid binding transcription factor activity, protein binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding Human SOX5 IntAct UniProtKB {GO:0005515=PMID:21262861, GO:2000741=PMID:21401405, GO:0003700=GO_REF:0000019, GO:0006366=PMID:8812465, GO:0044212=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0048709=GO_REF:0000019, GO:0051216=GO_REF:0000019, GO:0071560=PMID:21401405, GO:0021953=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0001701=GO_REF:0000019, GO:0045165=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0061036=PMID:21401405, GO:0032332=PMID:21401405, GO:0045892=GO_REF:0000019, GO:0060164=GO_REF:0000019} P35711 Transcription factor SOX-5 protein 20130415 {GO:0005515=IPI, GO:2000741=IDA, GO:0003700=IEA, GO:0006366=TAS, GO:0044212=IEA, GO:0046982=IEA, GO:0048709=IEA, GO:0051216=IEA, GO:0071560=IDA, GO:0021953=IEA, GO:0005634=IEA, GO:0001701=IEA, GO:0045165=IEA, GO:0045944=IEA, GO:0061036=IDA, GO:0032332=IDA, GO:0045892=IEA, GO:0060164=IEA} cartilage development, cell fate commitment, cellular response to transforming growth factor beta stimulus, central nervous system neuron differentiation, in utero embryonic development, negative regulation of transcription, DNA-dependent, oligodendrocyte differentiation, positive regulation of cartilage development, positive regulation of chondrocyte differentiation, positive regulation of mesenchymal stem cell differentiation, positive regulation of transcription from RNA polymerase II promoter, regulation of timing of neuron differentiation, transcription from RNA polymerase II promoter nucleus protein binding, protein heterodimerization activity, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding Human UniProtKB:O15266 SOX6 IntAct UniProtKB {GO:0005515=PMID:21262861, GO:0003700=PMID:1614875, GO:0044212=GO_REF:0000019, GO:0051216=GO_REF:0000019, GO:0071560=PMID:21401405, GO:0016458=GO_REF:0000019, GO:0005634=GO_REF:0000054, GO:0009791=GO_REF:0000019, GO:0042692=GO_REF:0000019, GO:0021778=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0048821=GO_REF:0000019, GO:0032332=PMID:21401405, GO:0006355=PMID:1614875, GO:2000741=PMID:21401405, GO:0046982=GO_REF:0000019, GO:0007275=GO_REF:0000002, GO:0035051=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0003677=PMID:1614875, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000019, GO:0000902=GO_REF:0000019, GO:0007517=PMID:11255018, GO:0061036=PMID:21401405} P35712 Transcription factor SOX-6 protein 20130415 {GO:0005515=IPI, GO:0003700=NAS, GO:0044212=IEA, GO:0051216=IEA, GO:0071560=IDA, GO:0016458=IEA, GO:0005634=IDA, GO:0009791=IEA, GO:0042692=IEA, GO:0021778=IEA, GO:0045944=IEA, GO:0048821=IEA, GO:0032332=IDA, GO:0006355=NAS, GO:2000741=IDA, GO:0046982=IEA, GO:0007275=IEA, GO:0035051=IEA, GO:0000122=IEA, GO:0001701=IEA, GO:0003677=NAS, GO:0006351=IEA, GO:0043565=IEA, GO:0000902=IEA, GO:0007517=NAS, GO:0061036=IDA} cardiocyte differentiation, cartilage development, cell morphogenesis, cellular response to transforming growth factor beta stimulus, erythrocyte development, gene silencing, in utero embryonic development, multicellular organismal development, muscle cell differentiation, muscle organ development, negative regulation of transcription from RNA polymerase II promoter, oligodendrocyte cell fate specification, positive regulation of cartilage development, positive regulation of chondrocyte differentiation, positive regulation of mesenchymal stem cell differentiation, positive regulation of transcription from RNA polymerase II promoter, post-embryonic development, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, protein binding, protein heterodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding Human UniProtKB:O15266 SOX7 BHF-UCL UniProtKB {GO:0001706=PMID:18682240, GO:0008285=PMID:19108950, GO:0003700=PMID:19108950, GO:0044212=GO_REF:0000024, GO:0003705=GO_REF:0000019, GO:0005634=PMID:18682240, GO:0003676=GO_REF:0000002, GO:0060828=PMID:19108950, GO:0043565=GO_REF:0000019, GO:0043280=PMID:19108950, GO:0005737=PMID:18819930, GO:0045893=GO_REF:0000019, GO:0045892=PMID:19108950} Q9BT81 Transcription factor SOX-7 protein 20110606 {GO:0001706=IDA, GO:0008285=IDA, GO:0003700=IDA, GO:0044212=ISS, GO:0003705=IEA, GO:0005634=IDA, GO:0003676=IEA, GO:0060828=IDA, GO:0043565=IEA, GO:0043280=IDA, GO:0005737=IDA, GO:0045893=IEA, GO:0045892=IDA} endoderm formation, negative regulation of cell proliferation, negative regulation of transcription, DNA-dependent, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of transcription, DNA-dependent, regulation of canonical Wnt receptor signaling pathway cytoplasm, nucleus RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, nucleic acid binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding Human UniProtKB:P40646 SOX8 UniProtKB UniProtKB {GO:0046533=GO_REF:0000019, GO:0072034=GO_REF:0000024, GO:0003700=GO_REF:0000019, GO:0060041=GO_REF:0000024, GO:0090184=GO_REF:0000024, GO:0048709=GO_REF:0000024, GO:0060221=GO_REF:0000024, GO:0001755=GO_REF:0000024, GO:0005634=PMID:18512230, GO:0007283=GO_REF:0000024, GO:0010817=GO_REF:0000024, GO:0045662=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0060009=GO_REF:0000024, GO:0072197=GO_REF:0000024, GO:0014015=GO_REF:0000024, GO:0045944=PMID:10662550, GO:0045444=GO_REF:0000024, GO:0048469=GO_REF:0000019, GO:0033690=GO_REF:0000024, GO:0090190=GO_REF:0000024, GO:0043066=GO_REF:0000024, GO:0000979=GO_REF:0000024, GO:0003677=PMID:10684944, GO:0001701=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0001649=GO_REF:0000024, GO:0048484=GO_REF:0000024, GO:0007165=GO_REF:0000024, GO:0072289=GO_REF:0000024, GO:0045165=GO_REF:0000024, GO:0060018=GO_REF:0000019, GO:0007422=GO_REF:0000024, GO:0061138=GO_REF:0000024, GO:0045893=GO_REF:0000024, GO:0060612=GO_REF:0000024, GO:0045892=GO_REF:0000024, GO:0008584=GO_REF:0000024, GO:0008134=GO_REF:0000019} P57073 Transcription factor SOX-8 protein 20110629 {GO:0046533=IEA, GO:0072034=ISS, GO:0003700=IEA, GO:0060041=ISS, GO:0090184=ISS, GO:0048709=ISS, GO:0060221=ISS, GO:0001755=ISS, GO:0005634=IDA, GO:0007283=ISS, GO:0010817=ISS, GO:0045662=ISS, GO:0005737=ISS, GO:0060009=ISS, GO:0072197=ISS, GO:0014015=ISS, GO:0045944=IDA, GO:0045444=ISS, GO:0048469=IEA, GO:0033690=ISS, GO:0090190=ISS, GO:0043066=ISS, GO:0000979=ISS, GO:0003677=NAS, GO:0001701=ISS, GO:0006351=IEA, GO:0001649=ISS, GO:0048484=ISS, GO:0007165=ISS, GO:0072289=ISS, GO:0045165=ISS, GO:0060018=IEA, GO:0007422=ISS, GO:0061138=ISS, GO:0045893=ISS, GO:0060612=ISS, GO:0045892=ISS, GO:0008584=ISS, GO:0008134=IEA} Sertoli cell development, adipose tissue development, astrocyte fate commitment, cell fate commitment, cell maturation, enteric nervous system development, fat cell differentiation, in utero embryonic development, male gonad development, metanephric nephron tubule formation, morphogenesis of a branching epithelium, negative regulation of apoptotic process, negative regulation of myoblast differentiation, negative regulation of photoreceptor cell differentiation, negative regulation of transcription, DNA-dependent, neural crest cell migration, oligodendrocyte differentiation, osteoblast differentiation, peripheral nervous system development, positive regulation of branching involved in ureteric bud morphogenesis, positive regulation of gliogenesis, positive regulation of kidney development, positive regulation of osteoblast proliferation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of hormone levels, renal vesicle induction, retina development in camera-type eye, retinal rod cell differentiation, signal transduction, spermatogenesis, transcription, DNA-dependent, ureter morphogenesis cytoplasm, nucleus DNA binding, RNA polymerase II core promoter sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human UniProtKB:Q04886 SOX9 HPA UniProtKB {GO:0005515=PMID:20530484, GO:0003700=PMID:8640233, GO:0072034=GO_REF:0000024, GO:0060041=GO_REF:0000024, GO:0051216=GO_REF:0000024, GO:0071300=PMID:12420222, GO:0048709=GO_REF:0000019, GO:0003705=PMID:20484372, GO:0071560=PMID:21401405, GO:0030879=GO_REF:0000019, GO:0007283=GO_REF:0000024, GO:0030155=GO_REF:0000019, GO:0045662=GO_REF:0000024, GO:0014032=GO_REF:0000019, GO:0001894=GO_REF:0000024, GO:0042127=GO_REF:0000024, GO:0035622=GO_REF:0000019, GO:0001708=GO_REF:0000024, GO:0006334=PMID:20484372, GO:0072190=GO_REF:0000019, GO:0030502=GO_REF:0000019, GO:2000138=GO_REF:0000019, GO:0001501=PMID:8640233, GO:0001503=GO_REF:0000019, GO:0001502=GO_REF:0000024, GO:0060729=GO_REF:0000024, GO:0034236=PMID:10805756, GO:0045732=GO_REF:0000019, GO:0002683=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0001837=GO_REF:0000024, GO:0072197=GO_REF:0000019, GO:0001046=PMID:20530484, GO:0035019=GO_REF:0000024, GO:0043425=GO_REF:0000019, GO:0042981=GO_REF:0000024, GO:0004672=GO_REF:0000024, GO:0071364=PMID:21512138, GO:0071504=PMID:21512138, GO:0019933=PMID:10805756, GO:0061036=PMID:21401405, GO:0061138=GO_REF:0000024, GO:0030903=GO_REF:0000019, GO:0060517=GO_REF:0000024, GO:0071260=PMID:21512138, GO:0019100=GO_REF:0000024, GO:2000020=PMID:21412441, GO:0046533=GO_REF:0000024, GO:0001658=GO_REF:0000019, GO:0003415=GO_REF:0000024, GO:0008013=GO_REF:0000019, GO:0003413=PMID:20676705, GO:0050680=GO_REF:0000024, GO:0010564=PMID:12420222, GO:0003188=GO_REF:0000019, GO:0060008=GO_REF:0000024, GO:0060009=GO_REF:0000019, GO:0007173=PMID:21512138, GO:0030198=GO_REF:0000019, GO:0070371=PMID:21512138, GO:0001942=GO_REF:0000024, GO:0050679=PMID:20103652, GO:0030916=GO_REF:0000024, GO:0003170=GO_REF:0000024, GO:0014068=GO_REF:0000024, GO:0003179=GO_REF:0000024, GO:0035326=PMID:10805756, GO:0043234=PMID:20530484, GO:0072289=GO_REF:0000024, GO:0071347=PMID:20079164, GO:0043491=GO_REF:0000019, GO:0060174=GO_REF:0000019, GO:0045893=PMID:20651055, GO:0045892=PMID:20651055, GO:0001158=GO_REF:0000024, GO:0008284=PMID:20651055, GO:0090184=GO_REF:0000024, GO:0060221=GO_REF:0000024, GO:0030858=GO_REF:0000024, GO:0030279=GO_REF:0000024, GO:0045944=PMID:8640233, GO:0090103=GO_REF:0000024, GO:0032332=PMID:21401405, GO:0030850=PMID:20103652, GO:0006338=PMID:20484372, GO:0032331=GO_REF:0000024, GO:0090090=GO_REF:0000024, GO:0090190=GO_REF:0000024, GO:0005667=GO_REF:0000019, GO:0060784=GO_REF:0000024, GO:0043066=GO_REF:0000024, GO:2000741=PMID:21401405, GO:0005730=GO_REF:0000052, GO:0070168=GO_REF:0000024, GO:0003203=GO_REF:0000024, GO:0002053=GO_REF:0000024, GO:0007165=GO_REF:0000024, GO:0001077=PMID:20484372, GO:0006461=PMID:20530484, GO:0060018=GO_REF:0000019, GO:0031018=GO_REF:0000019, GO:0003682=PMID:20484372, GO:0001934=GO_REF:0000024, GO:0010634=PMID:21512138, GO:0008584=PMID:8640233} P48436 Transcription factor SOX-9 protein 20080205 {GO:0005515=IPI, GO:0003700=IMP, GO:0072034=ISS, GO:0060041=ISS, GO:0051216=ISS, GO:0071300=IEP, GO:0048709=IEA, GO:0003705=IDA, GO:0071560=IDA, GO:0030879=IEA, GO:0007283=ISS, GO:0030155=IEA, GO:0045662=ISS, GO:0014032=IEA, GO:0001894=ISS, GO:0042127=ISS, GO:0035622=IEA, GO:0001708=ISS, GO:0006334=IDA, GO:0072190=IEA, GO:0030502=IEA, GO:2000138=IEA, GO:0001501=IMP, GO:0001503=IEA, GO:0001502=ISS, GO:0060729=ISS, GO:0034236=IPI, GO:0045732=IEA, GO:0002683=ISS, GO:0005634=IDA, GO:0001837=ISS, GO:0072197=IEA, GO:0001046=IDA, GO:0035019=ISS, GO:0043425=IEA, GO:0042981=ISS, GO:0004672=ISS, GO:0071364=ISS, GO:0071504=ISS, GO:0019933=IDA, GO:0061036=IDA, GO:0061138=ISS, GO:0030903=IEA, GO:0060517=ISS, GO:0071260=ISS, GO:0019100=ISS, GO:2000020=IDA, GO:0046533=ISS, GO:0001658=IEA, GO:0003415=ISS, GO:0008013=IEA, GO:0003413=IMP, GO:0050680=ISS, GO:0010564=IMP, GO:0003188=IEA, GO:0060008=ISS, GO:0060009=IEA, GO:0007173=ISS, GO:0030198=IEA, GO:0070371=ISS, GO:0001942=ISS, GO:0050679=IEP, GO:0030916=ISS, GO:0003170=ISS, GO:0014068=ISS, GO:0003179=ISS, GO:0035326=IDA, GO:0043234=IDA, GO:0072289=ISS, GO:0071347=IEP, GO:0043491=IEA, GO:0060174=IEA, GO:0045893=IMP, GO:0045892=IMP, GO:0001158=ISS, GO:0008284=IMP, GO:0090184=ISS, GO:0060221=ISS, GO:0030858=ISS, GO:0030279=ISS, GO:0045944=IDA, GO:0090103=ISS, GO:0032332=IDA, GO:0030850=IEP, GO:0006338=IDA, GO:0032331=ISS, GO:0090090=ISS, GO:0090190=ISS, GO:0005667=IEA, GO:0060784=ISS, GO:0043066=ISS, GO:2000741=IDA, GO:0005730=IDA, GO:0070168=ISS, GO:0003203=ISS, GO:0002053=ISS, GO:0007165=ISS, GO:0001077=IDA, GO:0006461=IDA, GO:0060018=IEA, GO:0031018=IEA, GO:0003682=IDA, GO:0001934=ISS, GO:0010634=IMP, GO:0008584=IMP} ERK1 and ERK2 cascade, Sertoli cell development, Sertoli cell differentiation, astrocyte fate commitment, branching involved in ureteric bud morphogenesis, cAMP-mediated signaling, cartilage condensation, cartilage development, cell fate specification, cellular response to epidermal growth factor stimulus, cellular response to heparin, cellular response to interleukin-1, cellular response to mechanical stimulus, cellular response to retinoic acid, cellular response to transforming growth factor beta stimulus, chondrocyte differentiation involved in endochondral bone morphogenesis, chondrocyte hypertrophy, chromatin remodeling, cochlea morphogenesis, endocardial cushion morphogenesis, endocrine pancreas development, epidermal growth factor receptor signaling pathway, epithelial cell proliferation involved in prostatic bud elongation, epithelial to mesenchymal transition, extracellular matrix organization, hair follicle development, heart valve development, heart valve formation, heart valve morphogenesis, intestinal epithelial structure maintenance, intrahepatic bile duct development, limb bud formation, male germ-line sex determination, male gonad development, mammary gland development, metanephric nephron tubule formation, morphogenesis of a branching epithelium, negative regulation of apoptotic process, negative regulation of biomineral tissue development, negative regulation of bone mineralization, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of chondrocyte differentiation, negative regulation of epithelial cell proliferation, negative regulation of immune system process, negative regulation of myoblast differentiation, negative regulation of ossification, negative regulation of photoreceptor cell differentiation, negative regulation of transcription, DNA-dependent, neural crest cell development, notochord development, nucleosome assembly, oligodendrocyte differentiation, ossification, otic vesicle formation, positive regulation of branching involved in ureteric bud morphogenesis, positive regulation of cartilage development, positive regulation of cell proliferation, positive regulation of cell proliferation involved in heart morphogenesis, positive regulation of chondrocyte differentiation, positive regulation of epithelial cell differentiation, positive regulation of epithelial cell migration, positive regulation of epithelial cell proliferation, positive regulation of kidney development, positive regulation of male gonad development, positive regulation of mesenchymal cell proliferation, positive regulation of mesenchymal stem cell differentiation, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of protein catabolic process, positive regulation of protein phosphorylation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, prostate gland development, protein complex assembly, protein kinase B signaling cascade, regulation of apoptotic process, regulation of cell adhesion, regulation of cell cycle process, regulation of cell proliferation, regulation of cell proliferation involved in tissue homeostasis, renal vesicle induction, retina development in camera-type eye, retinal rod cell differentiation, signal transduction, skeletal system development, somatic stem cell maintenance, spermatogenesis, tissue homeostasis, ureter morphogenesis, ureter urothelium development nucleolus, nucleus, protein complex, transcription factor complex RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, bHLH transcription factor binding, beta-catenin binding, chromatin binding, core promoter sequence-specific DNA binding, enhancer binding, enhancer sequence-specific DNA binding, protein binding, protein kinase A catalytic subunit binding, protein kinase activity, sequence-specific DNA binding transcription factor activity NOT Human SP1 BHF-UCL UniProtKB {GO:0000987=GO_REF:0000019, GO:0005515=PMID:21297662, GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_12627, GO:0003700=PMID:12169688, GO:0044212=PMID:18850004, GO:0042826=PMID:18850004, GO:0030324=GO_REF:0000019, GO:0048706=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0043353=GO_REF:0000019, GO:0042803=PMID:10393239, GO:0048596=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0003690=PMID:20371611, GO:0032993=GO_REF:0000019, GO:0045944=Reactome:REACT_120734, GO:0007179=Reactome:REACT_6844, GO:0044255=Reactome:REACT_22279, GO:0001103=GO_REF:0000024, GO:0035035=GO_REF:0000019, GO:0006355=PMID:12169688, GO:0060136=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0043425=GO_REF:0000024, GO:0001892=GO_REF:0000019, GO:0060216=GO_REF:0000019, GO:0000978=GO_REF:0000024, GO:0008022=PMID:10816420, GO:0001829=GO_REF:0000019, GO:0003677=PMID:12560508, GO:0000979=GO_REF:0000019, GO:0043923=PMID:2833704, GO:0035326=GO_REF:0000019, GO:0006351=Reactome:REACT_121061, GO:0043565=PMID:12169688, GO:0001889=GO_REF:0000019, GO:0001077=GO_REF:0000019, GO:0001503=GO_REF:0000019, GO:0030219=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0071837=PMID:16582099, GO:0005654=Reactome:REACT_147902, GO:0008270=GO_REF:0000002, GO:0045893=PMID:14580349, GO:0008134=PMID:20716579} P08047 Transcription factor Sp1 protein 20110311 {GO:0000987=IEA, GO:0005515=IPI, GO:0010467=TAS, GO:0006367=TAS, GO:0003700=IDA, GO:0044212=IDA, GO:0042826=IPI, GO:0030324=IEA, GO:0048706=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0043353=IEA, GO:0042803=IDA, GO:0048596=IEA, GO:0005737=IEA, GO:0003690=IDA, GO:0032993=IEA, GO:0045944=TAS, GO:0007179=TAS, GO:0044255=TAS, GO:0001103=ISS, GO:0035035=IEA, GO:0006355=IDA, GO:0060136=IEA, GO:0005730=IDA, GO:0043425=ISS, GO:0001892=IEA, GO:0060216=IEA, GO:0000978=ISS, GO:0008022=IPI, GO:0001829=IEA, GO:0003677=IDA, GO:0000979=IEA, GO:0043923=IDA, GO:0035326=IEA, GO:0006351=TAS, GO:0043565=IDA, GO:0001889=IEA, GO:0001077=IEA, GO:0001503=IEA, GO:0030219=IEA, GO:0019048=IEA, GO:0071837=IPI, GO:0005654=TAS, GO:0008270=IEA, GO:0045893=IDA, GO:0008134=IPI} cellular lipid metabolic process, definitive hemopoiesis, embryonic camera-type eye morphogenesis, embryonic placenta development, embryonic process involved in female pregnancy, embryonic skeletal system development, enucleate erythrocyte differentiation, gene expression, liver development, lung development, megakaryocyte differentiation, ossification, positive regulation by host of viral transcription, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, small molecule metabolic process, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, trophectodermal cell differentiation, virus-host interaction cytoplasm, nucleolus, nucleoplasm, nucleus, protein-DNA complex DNA binding, HMG box domain binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II core promoter sequence-specific DNA binding, RNA polymerase II repressing transcription factor binding, bHLH transcription factor binding, core promoter proximal region sequence-specific DNA binding, double-stranded DNA binding, enhancer binding, histone acetyltransferase binding, histone deacetylase binding, protein C-terminus binding, protein binding, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding, zinc ion binding Human SP100 BHF-UCL UniProtKB {GO:0005515=PMID:17000644, GO:0030870=PMID:15767676, GO:0070087=PMID:15882967, GO:0019221=Reactome:REACT_25229, GO:0005634=GO_REF:0000052, GO:0043433=PMID:15247905, GO:0042803=PMID:9636146, GO:0046826=PMID:17245429, GO:0005737=PMID:17245429, GO:0060337=PMID:8810287, GO:0000723=PMID:15767676, GO:0034340=PMID:9230084, GO:0034341=PMID:9230084, GO:0019900=PMID:14647468, GO:0006978=PMID:14647468, GO:0060333=PMID:8810287, GO:0003714=PMID:15247905, GO:0003713=PMID:14647468, GO:0019904=PMID:9636147, GO:1902041=PMID:17245429, GO:0045765=PMID:15592518, GO:0000122=PMID:15247905, GO:0003677=GO_REF:0000037, GO:1902044=PMID:17245429, GO:0043392=PMID:15247905, GO:0010596=PMID:15592518, GO:0016605=PMID:15247905, GO:0019048=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_25082, GO:0045893=PMID:14647468, GO:0051271=PMID:15247905} P23497 Nuclear autoantigen Sp-100 protein 20100127 {GO:0005515=IPI, GO:0030870=IDA, GO:0070087=IPI, GO:0019221=TAS, GO:0005634=IDA, GO:0043433=IDA, GO:0042803=IPI, GO:0046826=IMP, GO:0005737=IDA, GO:0060337=IC, GO:0000723=IMP, GO:0034340=IDA, GO:0034341=IDA, GO:0019900=IPI, GO:0006978=IDA, GO:0060333=IC, GO:0003714=IDA, GO:0003713=IDA, GO:0019904=IPI, GO:1902041=IMP, GO:0045765=IMP, GO:0000122=IDA, GO:0003677=IEA, GO:1902044=IMP, GO:0043392=IDA, GO:0010596=IMP, GO:0016605=IDA, GO:0019048=IEA, GO:0008270=IEA, GO:0005654=TAS, GO:0045893=IMP, GO:0051271=IMP} DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, cytokine-mediated signaling pathway, interferon-gamma-mediated signaling pathway, negative regulation of DNA binding, negative regulation of cellular component movement, negative regulation of endothelial cell migration, negative regulation of protein export from nucleus, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of Fas signaling pathway, regulation of angiogenesis, regulation of extrinsic apoptotic signaling pathway via death domain receptors, response to interferon-gamma, response to type I interferon, telomere maintenance, type I interferon-mediated signaling pathway, virus-host interaction Mre11 complex, PML body, cytoplasm, nucleoplasm, nucleus DNA binding, chromo shadow domain binding, kinase binding, protein binding, protein domain specific binding, protein homodimerization activity, transcription coactivator activity, transcription corepressor activity, zinc ion binding Human UniProtKB:P45973 SP110 GOC UniProtKB {GO:0007165=PMID:7693701, GO:0006355=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0004871=PMID:7693701, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9HB58 Sp110 nuclear body protein protein 20130413 {GO:0007165=TAS, GO:0006355=IEA, GO:0019048=IEA, GO:0005730=IDA, GO:0008270=IEA, GO:0005634=IDA, GO:0004871=TAS, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, signal transduction, transcription, DNA-dependent, virus-host interaction nucleolus, nucleus DNA binding, signal transducer activity, zinc ion binding Human SP140 GOC UniProtKB {GO:0006355=PMID:8695863, GO:0005737=GO_REF:0000052, GO:0003700=PMID:8695863, GO:0005730=GO_REF:0000052, GO:0006952=PMID:8910577, GO:0005654=PMID:8695863, GO:0005634=PMID:8910577, GO:0008270=GO_REF:0000002, GO:0005635=PMID:8695863, GO:0003677=GO_REF:0000037} Q13342 Nuclear body protein SP140 protein 20130413 {GO:0006355=TAS, GO:0005737=IDA, GO:0003700=TAS, GO:0005730=IDA, GO:0006952=TAS, GO:0005654=TAS, GO:0005634=TAS, GO:0008270=IEA, GO:0005635=TAS, GO:0003677=IEA} defense response, regulation of transcription, DNA-dependent cytoplasm, nuclear envelope, nucleolus, nucleoplasm, nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human SP140L UniProtKB UniProtKB {GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000002, GO:0003677=GO_REF:0000037} Q9H930 Nuclear body protein SP140-like protein protein 20130413 {GO:0008270=IEA, GO:0005634=IEA, GO:0003677=IEA} nucleus DNA binding, zinc ion binding Human UniProtKB-KW:KW-0238 SP2 HPA UniProtKB {GO:0006955=PMID:1341900, GO:0042826=PMID:17827154, GO:0006357=PMID:1341900, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q02086 Transcription factor Sp2 protein 20080205 {GO:0006955=TAS, GO:0042826=IPI, GO:0006357=TAS, GO:0005634=IDA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} immune response, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding, histone deacetylase binding, zinc ion binding Human SP3 IntAct UniProtKB {GO:0005515=PMID:10816575, GO:0000987=GO_REF:0000019, GO:0030324=GO_REF:0000019, GO:0048706=GO_REF:0000019, GO:0005634=PMID:12560508, GO:0043353=GO_REF:0000019, GO:0048596=GO_REF:0000019, GO:0003690=GO_REF:0000019, GO:0017053=GO_REF:0000019, GO:0030183=GO_REF:0000019, GO:0001779=GO_REF:0000019, GO:0030224=GO_REF:0000019, GO:0030851=GO_REF:0000019, GO:0006355=PMID:12560508, GO:0060136=GO_REF:0000019, GO:0001892=GO_REF:0000019, GO:0060216=GO_REF:0000019, GO:0001829=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0000979=GO_REF:0000019, GO:0001889=GO_REF:0000019, GO:0001078=GO_REF:0000019, GO:0001503=GO_REF:0000019, GO:0030217=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0016605=GO_REF:0000039, GO:0030219=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0045893=PMID:12771217, GO:0045892=PMID:20091743} Q02447 Transcription factor Sp3 protein 20130415 {GO:0005515=IPI, GO:0000987=IEA, GO:0030324=IEA, GO:0048706=IEA, GO:0005634=IC, GO:0043353=IEA, GO:0048596=IEA, GO:0003690=IEA, GO:0017053=IEA, GO:0030183=IEA, GO:0001779=IEA, GO:0030224=IEA, GO:0030851=IEA, GO:0006355=IDA, GO:0060136=IEA, GO:0001892=IEA, GO:0060216=IEA, GO:0001829=IEA, GO:0003676=IEA, GO:0000979=IEA, GO:0001889=IEA, GO:0001078=IEA, GO:0001503=IEA, GO:0030217=IEA, GO:0003682=IEA, GO:0016605=IEA, GO:0030219=IEA, GO:0008270=IEA, GO:0045893=IDA, GO:0045892=IMP} B cell differentiation, T cell differentiation, definitive hemopoiesis, embryonic camera-type eye morphogenesis, embryonic placenta development, embryonic process involved in female pregnancy, embryonic skeletal system development, enucleate erythrocyte differentiation, granulocyte differentiation, liver development, lung development, megakaryocyte differentiation, monocyte differentiation, natural killer cell differentiation, negative regulation of transcription, DNA-dependent, ossification, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, trophectodermal cell differentiation PML body, nucleus, transcriptional repressor complex RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, RNA polymerase II core promoter sequence-specific DNA binding, chromatin binding, core promoter proximal region sequence-specific DNA binding, double-stranded DNA binding, nucleic acid binding, protein binding, zinc ion binding Human UniProtKB:P03372 SP4 PINC UniProtKB {GO:0003700=GO_REF:0000019, GO:0006357=PMID:12560508, GO:0003713=PMID:7559627, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q02446 Transcription factor Sp4 protein 20030904 {GO:0003700=IEA, GO:0006357=IDA, GO:0003713=TAS, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, zinc ion binding Human SP5 UniProtKB UniProtKB {GO:0043565=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0060349=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0036342=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q6BEB4 Transcription factor Sp5 protein 20130413 {GO:0043565=IEA, GO:0006355=IEA, GO:0060349=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0036342=IEA, GO:0006351=IEA} bone morphogenesis, post-anal tail morphogenesis, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus sequence-specific DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 SP7 BHF-UCL UniProtKB {GO:0005737=PMID:18471237, GO:0006357=PMID:11792318, GO:0045944=PMID:18932205, GO:2000738=PMID:18932205, GO:0017151=PMID:17303075, GO:0008270=GO_REF:0000002, GO:0005634=PMID:18471237, GO:0060218=PMID:18932205, GO:0003677=PMID:11792318, GO:0006351=GO_REF:0000037, GO:0001649=PMID:11792318} Q8TDD2 Transcription factor Sp7 protein 20111118 {GO:0005737=IDA, GO:0006357=ISS, GO:0045944=IDA, GO:2000738=IDA, GO:0017151=ISS, GO:0008270=IEA, GO:0005634=IDA, GO:0060218=IDA, GO:0003677=ISS, GO:0006351=IEA, GO:0001649=ISS} hematopoietic stem cell differentiation, osteoblast differentiation, positive regulation of stem cell differentiation, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, nucleus DEAD/H-box RNA helicase binding, DNA binding, zinc ion binding Human UniProtKB:Q8VI67 SP8 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0009954=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0030326=GO_REF:0000019, GO:0009953=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8IXZ3 Transcription factor Sp8 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0009954=IEA, GO:0008270=IEA, GO:0030326=IEA, GO:0009953=IEA, GO:0003677=IEA, GO:0006351=IEA} dorsal/ventral pattern formation, embryonic limb morphogenesis, proximal/distal pattern formation, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 SPA17 BHF-UCL UniProtKB {GO:0007338=PMID:8688458, GO:0007165=GO_REF:0000002, GO:0005737=PMID:18421703, GO:0001539=PMID:18421703, GO:0016020=GO_REF:0000039, GO:0008603=GO_REF:0000002, GO:0031514=PMID:18421703, GO:0072372=PMID:18421703, GO:0007283=PMID:8688458, GO:0007339=GO_REF:0000002} Q15506 Sperm surface protein Sp17 protein 20110221 {GO:0007338=TAS, GO:0007165=IEA, GO:0005737=IDA, GO:0001539=IDA, GO:0016020=IEA, GO:0008603=IEA, GO:0031514=IDA, GO:0072372=IDA, GO:0007283=TAS, GO:0007339=IEA} binding of sperm to zona pellucida, ciliary or flagellar motility, signal transduction, single fertilization, spermatogenesis cytoplasm, membrane, motile cilium, primary cilium cAMP-dependent protein kinase regulator activity Human SPACA3 UniProtKB UniProtKB {GO:0005515=PMID:19945174, GO:0035036=GO_REF:0000019, GO:0050830=PMID:16150577, GO:0043032=PMID:11591365, GO:0003796=PMID:5154881, GO:0005576=PMID:16150577, GO:0009615=PMID:16150577, GO:0005764=PMID:5154881, GO:0009253=PMID:16150577, GO:0051635=PMID:16150577, GO:0050766=PMID:11591365, GO:0042117=PMID:11591365, GO:0016998=PMID:16150577, GO:0016021=GO_REF:0000037, GO:0030141=PMID:3470418, GO:0002080=GO_REF:0000039} Q8IXA5 Sperm acrosome membrane-associated protein 3 protein 20110208 {GO:0005515=IPI, GO:0035036=IEA, GO:0050830=TAS, GO:0043032=TAS, GO:0003796=IDA, GO:0005576=TAS, GO:0009615=TAS, GO:0005764=IDA, GO:0009253=TAS, GO:0051635=TAS, GO:0050766=TAS, GO:0042117=TAS, GO:0016998=TAS, GO:0016021=IEA, GO:0030141=IDA, GO:0002080=IEA} cell wall macromolecule catabolic process, defense response to Gram-positive bacterium, monocyte activation, peptidoglycan catabolic process, positive regulation of macrophage activation, positive regulation of phagocytosis, response to virus, sperm-egg recognition acrosomal membrane, extracellular region, integral to membrane, lysosome, secretory granule bacterial cell surface binding, lysozyme activity, protein binding Human UniProtKB:P21754 SPAG1 UniProtKB UniProtKB {GO:0007338=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0016787=GO_REF:0000037, GO:0005525=GO_REF:0000037} Q07617 Sperm-associated antigen 1 protein 20130413 {GO:0007338=IEA, GO:0005737=IEA, GO:0016787=IEA, GO:0005525=IEA} single fertilization cytoplasm GTP binding, hydrolase activity Human UniProtKB-SubCell:SL-0086 SPAG16 UniProtKB UniProtKB {GO:0042384=GO_REF:0000024, GO:0019901=GO_REF:0000019, GO:0005874=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0035085=GO_REF:0000024} Q8N0X2 Sperm-associated antigen 16 protein protein 20110202 {GO:0042384=ISS, GO:0019901=IEA, GO:0005874=IEA, GO:0005634=IEA, GO:0007283=IEA, GO:0035085=ISS} cilium assembly, spermatogenesis cilium axoneme, microtubule, nucleus protein kinase binding Human UniProtKB:Q8K450 SPAG4 PINC UniProtKB {GO:0005929=GO_REF:0000037, GO:0005737=GO_REF:0000037, GO:0005198=PMID:9691178, GO:0007283=PMID:9691178, GO:0016021=GO_REF:0000037, GO:0005856=GO_REF:0000039} Q9NPE6 Sperm-associated antigen 4 protein protein 20050308 {GO:0005929=IEA, GO:0005737=IEA, GO:0005198=TAS, GO:0007283=TAS, GO:0016021=IEA, GO:0005856=IEA} spermatogenesis cilium, cytoplasm, cytoskeleton, integral to membrane structural molecule activity Human SPAG5 HPA UniProtKB {GO:0005515=PMID:21402792, GO:0072686=PMID:21402792, GO:0051988=PMID:21402792, GO:0048015=PMID:15504738, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0035371=PMID:21402792, GO:0005737=GO_REF:0000052, GO:0000922=GO_REF:0000039, GO:0007049=PMID:15504738, GO:0000070=PMID:21402792, GO:0007059=PMID:21402792, GO:0000777=GO_REF:0000039, GO:0000776=PMID:21402792, GO:0007051=PMID:21402792, GO:0000090=PMID:21402792, GO:0051301=GO_REF:0000037} Q96R06 Sperm-associated antigen 5 protein 20101115 {GO:0005515=IPI, GO:0072686=IDA, GO:0051988=IMP, GO:0048015=NAS, GO:0005730=IDA, GO:0005634=IDA, GO:0035371=IDA, GO:0005737=IDA, GO:0000922=IEA, GO:0007049=NAS, GO:0000070=IMP, GO:0007059=IMP, GO:0000777=IEA, GO:0000776=IDA, GO:0007051=IMP, GO:0000090=IMP, GO:0051301=IEA} cell cycle, cell division, chromosome segregation, mitotic anaphase, mitotic sister chromatid segregation, phosphatidylinositol-mediated signaling, regulation of attachment of spindle microtubules to kinetochore, spindle organization condensed chromosome kinetochore, cytoplasm, kinetochore, microtubule plus end, mitotic spindle, nucleolus, nucleus, spindle pole protein binding Human SPAG6 LIFEdb UniProtKB {GO:0005929=GO_REF:0000037, GO:0005737=GO_REF:0000037, GO:0005930=PMID:10493827, GO:0015630=GO_REF:0000054, GO:0030030=GO_REF:0000037, GO:0005874=GO_REF:0000037, GO:0007286=PMID:10493827, GO:0030317=GO_REF:0000019} O75602 Sperm-associated antigen 6 protein 20100607 {GO:0005929=IEA, GO:0005737=IEA, GO:0005930=TAS, GO:0015630=IDA, GO:0030030=IEA, GO:0005874=IEA, GO:0007286=TAS, GO:0030317=IEA} cell projection organization, sperm motility, spermatid development axoneme, cilium, cytoplasm, microtubule, microtubule cytoskeleton Human SPAG7 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002} O75391 Sperm-associated antigen 7 protein 20130413 {GO:0005634=IEA, GO:0003676=IEA} nucleus nucleic acid binding Human UniProtKB-SubCell:SL-0191 SPAG8 UniProtKB UniProtKB {GO:0008017=GO_REF:0000002, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000019, GO:0016020=PMID:8788182, GO:0001669=GO_REF:0000039, GO:0045944=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0032092=GO_REF:0000019} Q99932 Sperm-associated antigen 8 protein 20061106 {GO:0008017=IEA, GO:0008150=ND, GO:0003674=ND, GO:0005737=IEA, GO:0016020=NAS, GO:0001669=IEA, GO:0045944=IEA, GO:0005634=IEA, GO:0032092=IEA} biological_process, positive regulation of protein binding, positive regulation of transcription from RNA polymerase II promoter acrosomal vesicle, cytoplasm, membrane, nucleus microtubule binding, molecular_function Human SPAG9 HPA UniProtKB {GO:0048471=GO_REF:0000039, GO:0030335=PMID:18826971, GO:0090074=GO_REF:0000019, GO:0001669=GO_REF:0000039, GO:0007257=GO_REF:0000019, GO:0007283=PMID:9480848, GO:0005829=Reactome:REACT_21288, GO:0042692=Reactome:REACT_21303, GO:0005737=GO_REF:0000052, GO:0051149=Reactome:REACT_21402, GO:0045666=GO_REF:0000019, GO:0042147=PMID:19056739, GO:0051260=GO_REF:0000019, GO:0019894=GO_REF:0000019, GO:0048273=GO_REF:0000019, GO:0016021=PMID:9480848, GO:0008432=GO_REF:0000019, GO:0051146=GO_REF:0000019} O60271 C-Jun-amino-terminal kinase-interacting protein 4 protein 20110516 {GO:0048471=IEA, GO:0030335=IMP, GO:0090074=IEA, GO:0001669=IEA, GO:0007257=IEA, GO:0007283=TAS, GO:0005829=TAS, GO:0042692=TAS, GO:0005737=IDA, GO:0051149=TAS, GO:0045666=IEA, GO:0042147=IDA, GO:0051260=IEA, GO:0019894=IEA, GO:0048273=IEA, GO:0016021=TAS, GO:0008432=IEA, GO:0051146=IEA} activation of JUN kinase activity, muscle cell differentiation, negative regulation of protein homodimerization activity, positive regulation of cell migration, positive regulation of muscle cell differentiation, positive regulation of neuron differentiation, protein homooligomerization, retrograde transport, endosome to Golgi, spermatogenesis, striated muscle cell differentiation acrosomal vesicle, cytoplasm, cytosol, integral to membrane, perinuclear region of cytoplasm JUN kinase binding, kinesin binding, mitogen-activated protein kinase p38 binding Human SPANXB1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000039, GO:0007286=PMID:10906052, GO:0005634=PMID:10906052} Q9NS25 Sperm protein associated with the nucleus on the X chromosome B/F protein 20061026 {GO:0003674=ND, GO:0005737=IEA, GO:0007286=NAS, GO:0005634=TAS} spermatid development cytoplasm, nucleus molecular_function Human SPANXN3 null null {} null null null null {} null null null SPARC BHF-UCL UniProtKB {GO:0005515=PMID:3402455, GO:0030324=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0005518=PMID:7034958, GO:0043434=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0033591=GO_REF:0000019, GO:0005615=GO_REF:0000002, GO:0051591=GO_REF:0000019, GO:0007507=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0031093=Reactome:REACT_21351, GO:0034097=GO_REF:0000019, GO:0010288=GO_REF:0000019, GO:0048839=GO_REF:0000019, GO:0031988=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0050840=GO_REF:0000019, GO:0005578=PMID:7034958, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_21351, GO:0051384=GO_REF:0000019, GO:0005604=GO_REF:0000039, GO:0031012=GO_REF:0000019, GO:0007165=GO_REF:0000002, GO:0051592=GO_REF:0000019, GO:0001503=GO_REF:0000019, GO:0071363=GO_REF:0000019, GO:0009629=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0042060=GO_REF:0000019, GO:0046686=GO_REF:0000019} P09486 SPARC protein 20080928 {GO:0005515=IPI, GO:0030324=IEA, GO:0045471=IEA, GO:0005518=TAS, GO:0043434=IEA, GO:0005634=IEA, GO:0033591=IEA, GO:0005615=IEA, GO:0051591=IEA, GO:0007507=IEA, GO:0005737=IEA, GO:0042127=IEA, GO:0032496=IEA, GO:0031093=TAS, GO:0034097=IEA, GO:0010288=IEA, GO:0048839=IEA, GO:0031988=IEA, GO:0005509=IEA, GO:0050840=IEA, GO:0005578=TAS, GO:0030168=TAS, GO:0005576=TAS, GO:0051384=IEA, GO:0005604=IEA, GO:0031012=IEA, GO:0007165=IEA, GO:0051592=IEA, GO:0001503=IEA, GO:0071363=IEA, GO:0009629=IEA, GO:0007596=TAS, GO:0002576=TAS, GO:0042060=IEA, GO:0046686=IEA} blood coagulation, cellular response to growth factor stimulus, heart development, inner ear development, lung development, ossification, platelet activation, platelet degranulation, regulation of cell proliferation, response to L-ascorbic acid, response to cAMP, response to cadmium ion, response to calcium ion, response to cytokine stimulus, response to ethanol, response to glucocorticoid stimulus, response to gravity, response to lead ion, response to lipopolysaccharide, response to peptide hormone stimulus, signal transduction, wound healing basement membrane, cytoplasm, extracellular matrix, extracellular region, extracellular space, membrane-bounded vesicle, nucleus, platelet alpha granule lumen, proteinaceous extracellular matrix calcium ion binding, collagen binding, extracellular matrix binding, protein binding Human UniProtKB:P07996 SPARCL1 UniProtKB UniProtKB {GO:0007165=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0005578=GO_REF:0000039, GO:0005615=GO_REF:0000002} Q14515 SPARC-like protein 1 protein 20130413 {GO:0007165=IEA, GO:0005509=IEA, GO:0005578=IEA, GO:0005615=IEA} signal transduction extracellular space, proteinaceous extracellular matrix calcium ion binding Human UniProtKB-SubCell:SL-0111 SPAST MGI UniProtKB {GO:0008017=PMID:15716377, GO:0005515=PMID:20200447, GO:0008219=GO_REF:0000037, GO:0048471=GO_REF:0000039, GO:0005783=PMID:19000169, GO:0001578=PMID:16219033, GO:0005634=PMID:16026783, GO:0007109=PMID:19000169, GO:0034214=PMID:17389232, GO:0030154=GO_REF:0000037, GO:0051013=PMID:15716377, GO:0005737=PMID:21545838, GO:0015630=PMID:19000169, GO:0051260=PMID:17389232, GO:0005815=GO_REF:0000039, GO:0043014=PMID:17389232, GO:0005874=GO_REF:0000019, GO:0048487=PMID:17389232, GO:0005819=GO_REF:0000039, GO:0030496=PMID:19000169, GO:0031410=PMID:21545838, GO:0005524=GO_REF:0000037, GO:0007399=GO_REF:0000037, GO:0008568=PMID:16219033, GO:0006888=PMID:19000169, GO:0007049=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005768=PMID:19000169} Q9UBP0 Spastin protein 20120903 {GO:0008017=IDA, GO:0005515=IPI, GO:0008219=IEA, GO:0048471=IEA, GO:0005783=IDA, GO:0001578=IDA, GO:0005634=IDA, GO:0007109=IMP, GO:0034214=IDA, GO:0030154=IEA, GO:0051013=IDA, GO:0005737=IDA, GO:0015630=IDA, GO:0051260=IDA, GO:0005815=IEA, GO:0043014=IPI, GO:0005874=IEA, GO:0048487=IPI, GO:0005819=IEA, GO:0030496=IDA, GO:0031410=IDA, GO:0005524=IEA, GO:0007399=IEA, GO:0008568=IDA, GO:0006888=IMP, GO:0007049=IEA, GO:0016021=IEA, GO:0005768=IDA} ER to Golgi vesicle-mediated transport, cell cycle, cell death, cell differentiation, cytokinesis, completion of separation, microtubule bundle formation, microtubule severing, nervous system development, protein hexamerization, protein homooligomerization cytoplasm, cytoplasmic vesicle, endoplasmic reticulum, endosome, integral to membrane, microtubule, microtubule cytoskeleton, microtubule organizing center, midbody, nucleus, perinuclear region of cytoplasm, spindle ATP binding, alpha-tubulin binding, beta-tubulin binding, microtubule binding, microtubule-severing ATPase activity, protein binding Human SPATA13 HPA UniProtKB {GO:0030334=PMID:17599059, GO:0005515=PMID:17145773, GO:0035023=GO_REF:0000002, GO:0030032=PMID:17599059, GO:0005730=GO_REF:0000052, GO:0032587=PMID:19151759, GO:0005634=GO_REF:0000052, GO:0030175=PMID:17599059, GO:0030027=PMID:19151759, GO:0005622=GO_REF:0000002, GO:0005085=PMID:19934221, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0016477=PMID:19151759, GO:0046847=PMID:17599059, GO:0005089=GO_REF:0000002, GO:0030676=PMID:17599059} Q96N96 Spermatogenesis-associated protein 13 protein 20111111 {GO:0030334=IMP, GO:0005515=IPI, GO:0035023=IEA, GO:0030032=IMP, GO:0005730=IDA, GO:0032587=IDA, GO:0005634=IDA, GO:0030175=IDA, GO:0030027=IDA, GO:0005622=IEA, GO:0005085=IDA, GO:0005737=IDA, GO:0005543=IEA, GO:0016477=IMP, GO:0046847=IMP, GO:0005089=IEA, GO:0030676=IMP} cell migration, filopodium assembly, lamellipodium assembly, regulation of Rho protein signal transduction, regulation of cell migration cytoplasm, filopodium, intracellular, lamellipodium, nucleolus, nucleus, ruffle membrane Rac guanyl-nucleotide exchange factor activity, Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, phospholipid binding, protein binding Human SPATA16 UniProtKB UniProtKB {GO:0005794=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q9BXB7 Spermatogenesis-associated protein 16 protein 20130413 {GO:0005794=IEA, GO:0007275=IEA, GO:0007283=IEA, GO:0030154=IEA} cell differentiation, multicellular organismal development, spermatogenesis Golgi apparatus Human UniProtKB-SubCell:SL-0132 SPATA18 UniProtKB UniProtKB {GO:0005515=PMID:22292033, GO:0005737=PMID:21264228, GO:0044447=GO_REF:0000019, GO:0035694=PMID:21264228, GO:0035695=PMID:21264228, GO:0033554=PMID:21264228, GO:0005741=PMID:21264228, GO:0006974=PMID:21264221, GO:0043231=PMID:21264228} Q8TC71 Mitochondria-eating protein protein 20120329 {GO:0005515=IPI, GO:0005737=IDA, GO:0044447=IEA, GO:0035694=IMP, GO:0035695=IMP, GO:0033554=IDA, GO:0005741=IDA, GO:0006974=IDA, GO:0043231=IDA} cellular response to stress, mitochondrial protein catabolic process, mitochondrion degradation by induced vacuole formation, response to DNA damage stimulus axoneme part, cytoplasm, intracellular membrane-bounded organelle, mitochondrial outer membrane protein binding Human UniProtKB:Q12983 SPATA2 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0005737=PMID:10222154, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0007283=PMID:10222154, GO:0030154=GO_REF:0000037} Q9UM82 Spermatogenesis-associated protein 2 protein 20010817 {GO:0003674=ND, GO:0005737=IDA, GO:0005634=IEA, GO:0007275=IEA, GO:0007283=NAS, GO:0030154=IEA} cell differentiation, multicellular organismal development, spermatogenesis cytoplasm, nucleus molecular_function Human SPATA20 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0003824=GO_REF:0000002, GO:0030154=GO_REF:0000037, GO:0006013=GO_REF:0000002, GO:0004476=GO_REF:0000002} Q8TB22 Spermatogenesis-associated protein 20 protein 20130413 {GO:0005576=IEA, GO:0007275=IEA, GO:0007283=IEA, GO:0003824=IEA, GO:0030154=IEA, GO:0006013=IEA, GO:0004476=IEA} cell differentiation, mannose metabolic process, multicellular organismal development, spermatogenesis extracellular region catalytic activity, mannose-6-phosphate isomerase activity Human UniProtKB-SubCell:SL-0243 SPATA21 InterPro UniProtKB {GO:0005509=GO_REF:0000002} Q7Z572 Spermatogenesis-associated protein 21 protein 20130413 {GO:0005509=IEA} calcium ion binding Human InterPro:IPR002048|InterPro:IPR011992 SPATA22 null null {} null null null null {} null null null SPATA24 HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000039, GO:0005654=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0007283=GO_REF:0000037, GO:0003677=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8N799 Spermatogenesis-associated protein 24 protein 20111111 {GO:0006355=IEA, GO:0005737=IDA, GO:0005730=IEA, GO:0005654=IEA, GO:0007275=IEA, GO:0005634=IDA, GO:0007283=IEA, GO:0003677=IEA, GO:0042803=IEA, GO:0030154=IEA, GO:0006351=IEA} cell differentiation, multicellular organismal development, regulation of transcription, DNA-dependent, spermatogenesis, transcription, DNA-dependent cytoplasm, nucleolus, nucleoplasm, nucleus DNA binding, protein homodimerization activity Human SPATA2L null null {} null null null null {} null null null SPATA4 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000019, GO:0006915=PMID:12019456, GO:0005575=GO_REF:0000015, GO:0007283=PMID:12019456} Q8NEY3 Spermatogenesis-associated protein 4 protein 20061026 {GO:0003674=ND, GO:0005737=IEA, GO:0006915=IEP, GO:0005575=ND, GO:0007283=IEP} apoptotic process, spermatogenesis cellular_component, cytoplasm molecular_function Human SPATA5 LIFEdb UniProtKB {GO:0005739=GO_REF:0000039, GO:0005737=GO_REF:0000054, GO:0017111=GO_REF:0000002, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q8NB90 Spermatogenesis-associated protein 5 protein 20100607 {GO:0005739=IEA, GO:0005737=IDA, GO:0017111=IEA, GO:0007275=IEA, GO:0007283=IEA, GO:0005524=IEA, GO:0030154=IEA} cell differentiation, multicellular organismal development, spermatogenesis cytoplasm, mitochondrion ATP binding, nucleoside-triphosphatase activity Human SPATA5L1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0017111=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q9BVQ7 Spermatogenesis-associated protein 5-like protein 1 protein 20130413 {GO:0005737=IEA, GO:0017111=IEA, GO:0005524=IEA} cytoplasm ATP binding, nucleoside-triphosphatase activity Human UniProtKB-SubCell:SL-0086 SPATA7 UniProtKB UniProtKB {GO:0007601=GO_REF:0000037, GO:0050896=GO_REF:0000037} Q9P0W8 Spermatogenesis-associated protein 7 protein 20130413 {GO:0007601=IEA, GO:0050896=IEA} response to stimulus, visual perception Human UniProtKB-KW:KW-0716 SPATC1 MGI UniProtKB {GO:0005813=PMID:20542897, GO:0005737=GO_REF:0000039, GO:0043015=GO_REF:0000019} Q76KD6 Speriolin protein 20130124 {GO:0005813=IDA, GO:0005737=IEA, GO:0043015=IEA} centrosome, cytoplasm gamma-tubulin binding Human SPATS1 null null {} null null null null {} null null null SPATS2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q86XZ4 Spermatogenesis-associated serine-rich protein 2 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 SPATS2L UniProtKB UniProtKB {GO:0043234=GO_REF:0000054, GO:0005737=GO_REF:0000039, GO:0005730=GO_REF:0000039} Q9NUQ6 SPATS2-like protein protein 20130413 {GO:0043234=IDA, GO:0005737=IEA, GO:0005730=IEA} cytoplasm, nucleolus, protein complex Human UniProtKB-SubCell:SL-0086 SPC24 Reactome UniProtKB {GO:0000236=Reactome:REACT_682, GO:0000087=Reactome:REACT_910, GO:0000777=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0031262=PMID:14699129, GO:0005829=Reactome:REACT_150414, GO:0051301=GO_REF:0000037} Q8NBT2 Kinetochore protein Spc24 protein 20130213 {GO:0000236=TAS, GO:0000087=TAS, GO:0000777=IEA, GO:0005634=IEA, GO:0000278=TAS, GO:0000090=TAS, GO:0031262=IDA, GO:0005829=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, cell division, mitotic anaphase, mitotic cell cycle, mitotic prometaphase Ndc80 complex, condensed chromosome kinetochore, cytosol, nucleus Human SPC25 Reactome UniProtKB {GO:0005515=PMID:14699129, GO:0000236=Reactome:REACT_682, GO:0007059=PMID:14699129, GO:0000087=Reactome:REACT_910, GO:0000777=PMID:14699129, GO:0005634=GO_REF:0000039, GO:0000278=Reactome:REACT_152, GO:0007052=PMID:14699129, GO:0000090=Reactome:REACT_1275, GO:0031262=PMID:14699129, GO:0005829=Reactome:REACT_150414, GO:0051301=GO_REF:0000037} Q9HBM1 Kinetochore protein Spc25 protein 20130213 {GO:0005515=IPI, GO:0000236=TAS, GO:0007059=IMP, GO:0000087=TAS, GO:0000777=IDA, GO:0005634=IEA, GO:0000278=TAS, GO:0007052=IMP, GO:0000090=TAS, GO:0031262=IDA, GO:0005829=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, cell division, chromosome segregation, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, mitotic spindle organization Ndc80 complex, condensed chromosome kinetochore, cytosol, nucleus protein binding Human SPCS1 Reactome UniProtKB {GO:0005787=PMID:8632014, GO:0010467=Reactome:REACT_71, GO:0006614=Reactome:REACT_115902, GO:0030176=PMID:8632014, GO:0006412=Reactome:REACT_1014, GO:0003674=GO_REF:0000015, GO:0050796=Reactome:REACT_23974, GO:0006508=PMID:8632014, GO:0005789=Reactome:REACT_19296, GO:0043022=GO_REF:0000019, GO:0008233=GO_REF:0000037, GO:0016021=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0006465=GO_REF:0000002} Q9Y6A9 Signal peptidase complex subunit 1 protein 20130213 {GO:0005787=TAS, GO:0010467=TAS, GO:0006614=TAS, GO:0030176=IDA, GO:0006412=TAS, GO:0003674=ND, GO:0050796=TAS, GO:0006508=TAS, GO:0005789=TAS, GO:0043022=IEA, GO:0008233=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0006465=IEA} SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, proteolysis, regulation of insulin secretion, signal peptide processing, translation endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane, integral to membrane, signal peptidase complex molecular_function, peptidase activity, ribosome binding Human SPCS2 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0005787=GO_REF:0000002, GO:0050796=Reactome:REACT_23974, GO:0006614=Reactome:REACT_115902, GO:0005789=Reactome:REACT_19296, GO:0006508=GO_REF:0000037, GO:0008233=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0006465=GO_REF:0000002} Q15005 Signal peptidase complex subunit 2 protein 20130213 {GO:0010467=TAS, GO:0005787=IEA, GO:0050796=TAS, GO:0006614=TAS, GO:0005789=TAS, GO:0006508=IEA, GO:0008233=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0006412=TAS, GO:0006465=IEA} SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, proteolysis, regulation of insulin secretion, signal peptide processing, translation endoplasmic reticulum membrane, integral to membrane, signal peptidase complex peptidase activity Human SPCS3 LIFEdb UniProtKB {GO:0010467=Reactome:REACT_71, GO:0005787=GO_REF:0000002, GO:0050796=Reactome:REACT_23974, GO:0005783=GO_REF:0000054, GO:0006614=Reactome:REACT_115902, GO:0005789=Reactome:REACT_19296, GO:0006508=GO_REF:0000037, GO:0008233=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0006465=GO_REF:0000002} P61009 Signal peptidase complex subunit 3 protein 20100607 {GO:0010467=TAS, GO:0005787=IEA, GO:0050796=TAS, GO:0005783=IDA, GO:0006614=TAS, GO:0005789=TAS, GO:0006508=IEA, GO:0008233=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0006412=TAS, GO:0006465=IEA} SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, proteolysis, regulation of insulin secretion, signal peptide processing, translation endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, signal peptidase complex peptidase activity Human SPDEF BHF-UCL UniProtKB {GO:0060576=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0043065=PMID:21229552, GO:0003700=GO_REF:0000002, GO:0010455=GO_REF:0000019, GO:0010454=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0007275=PMID:10625666, GO:0005634=GO_REF:0000039, GO:0000122=PMID:21229552, GO:0006351=GO_REF:0000037, GO:0060480=GO_REF:0000019} O95238 SAM pointed domain-containing Ets transcription factor protein 20110120 {GO:0060576=IEA, GO:0043565=IEA, GO:0043065=IDA, GO:0003700=IEA, GO:0010455=IEA, GO:0010454=IEA, GO:0045944=IEA, GO:0007275=TAS, GO:0005634=IEA, GO:0000122=IDA, GO:0006351=IEA, GO:0060480=IEA} intestinal epithelial cell development, lung goblet cell differentiation, multicellular organismal development, negative regulation of cell fate commitment, negative regulation of transcription from RNA polymerase II promoter, positive regulation of apoptotic process, positive regulation of cell fate commitment, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human SPDYA UniProtKB UniProtKB {GO:0000082=PMID:11980914, GO:0008284=PMID:11980914, GO:0019901=PMID:12839962, GO:0045737=GO_REF:0000019, GO:0005634=PMID:11980914, GO:0007275=GO_REF:0000037, GO:0006974=PMID:12839962, GO:0007140=GO_REF:0000024} Q5MJ70 Speedy protein A protein 20120815 {GO:0000082=IDA, GO:0008284=IDA, GO:0019901=IPI, GO:0045737=IEA, GO:0005634=IDA, GO:0007275=IEA, GO:0006974=IDA, GO:0007140=ISS} G1/S transition of mitotic cell cycle, male meiosis, multicellular organismal development, positive regulation of cell proliferation, positive regulation of cyclin-dependent protein kinase activity, response to DNA damage stimulus nucleus protein kinase binding Human UniProtKB:Q5IBH7 SPECC1 MGI UniProtKB {GO:0005634=GO_REF:0000039, GO:0007155=PMID:21703590} Q5M775 Cytospin-B protein 20130212 {GO:0005634=IEA, GO:0007155=IDA} cell adhesion nucleus Human SPECC1L UniProtKB UniProtKB {GO:0007049=GO_REF:0000037, GO:0005737=GO_REF:0000037, GO:0005819=GO_REF:0000039, GO:0005921=GO_REF:0000039, GO:0051301=GO_REF:0000037} Q69YQ0 Cytospin-A protein 20130413 {GO:0007049=IEA, GO:0005737=IEA, GO:0005819=IEA, GO:0005921=IEA, GO:0051301=IEA} cell cycle, cell division cytoplasm, gap junction, spindle Human UniProtKB-SubCell:SL-0124 SPEF1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0035085=GO_REF:0000024, GO:0005856=GO_REF:0000037} Q9Y4P9 Sperm flagellar protein 1 protein 20110413 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND, GO:0035085=ISS, GO:0005856=IEA} biological_process cellular_component, cilium axoneme, cytoskeleton molecular_function Human UniProtKB:Q0IH24 SPEF2 ENSEMBL UniProtKB {GO:0006139=GO_REF:0000002, GO:0005794=GO_REF:0000019, GO:0002177=GO_REF:0000019, GO:0097225=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0019205=GO_REF:0000002} Q9C093 Sperm flagellar protein 2 protein 20130413 {GO:0006139=IEA, GO:0005794=IEA, GO:0002177=IEA, GO:0097225=IEA, GO:0046983=IEA, GO:0005524=IEA, GO:0019205=IEA} nucleobase-containing compound metabolic process Golgi apparatus, manchette, sperm midpiece ATP binding, nucleobase-containing compound kinase activity, protein dimerization activity Human Ensembl:ENSMUSP00000035762 SPEG PINC UniProtKB {GO:0042692=GO_REF:0000019, GO:0008285=PMID:8663449, GO:0007517=PMID:8663449, GO:0004674=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0005524=GO_REF:0000037} Q15772 Striated muscle preferentially expressed protein kinase protein 20030904 {GO:0042692=IEA, GO:0008285=TAS, GO:0007517=TAS, GO:0004674=IEA, GO:0005634=IEA, GO:0005524=IEA} muscle cell differentiation, muscle organ development, negative regulation of cell proliferation nucleus ATP binding, protein serine/threonine kinase activity Human SPEN HPA UniProtKB {GO:0001191=PMID:16287852, GO:0005515=PMID:16287852, GO:0003700=GO_REF:0000019, GO:0003723=GO_REF:0000037, GO:0003714=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000122=PMID:16287852, GO:0003676=GO_REF:0000002, GO:0000166=GO_REF:0000002, GO:0007219=GO_REF:0000037, GO:0003697=GO_REF:0000019, GO:0050769=PMID:16287852, GO:0017053=PMID:16287852, GO:0019048=GO_REF:0000037, GO:0001085=PMID:16287852, GO:0045893=GO_REF:0000019, GO:0045892=PMID:16129689} Q96T58 Msx2-interacting protein protein 20090616 {GO:0001191=IDA, GO:0005515=IPI, GO:0003700=IEA, GO:0003723=IEA, GO:0003714=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0000122=IDA, GO:0003676=IEA, GO:0000166=IEA, GO:0007219=IEA, GO:0003697=IEA, GO:0050769=IMP, GO:0017053=IDA, GO:0019048=IEA, GO:0001085=IPI, GO:0045893=IEA, GO:0045892=IDA} Notch signaling pathway, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of neurogenesis, positive regulation of transcription, DNA-dependent, virus-host interaction nucleolus, nucleus, transcriptional repressor complex RNA binding, RNA polymerase II transcription factor binding, RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription, nucleic acid binding, nucleotide binding, protein binding, sequence-specific DNA binding transcription factor activity, single-stranded DNA binding, transcription corepressor activity NOT Human SPERT HGNC UniProtKB {GO:0016023=PMID:12204287} Q8NA61 Spermatid-associated protein protein 20060322 {GO:0016023=ISS} cytoplasmic membrane-bounded vesicle Human UniProtKB:Q32MG2 SPG11 HPA UniProtKB {GO:0005515=PMID:20613862, GO:0008219=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0031410=PMID:21545838, GO:0016021=GO_REF:0000037, GO:0005829=GO_REF:0000039} Q96JI7 Spatacsin protein 20111111 {GO:0005515=IPI, GO:0008219=IEA, GO:0005737=IDA, GO:0005886=IDA, GO:0005730=IDA, GO:0031410=IDA, GO:0016021=IEA, GO:0005829=IEA} cell death cytoplasm, cytoplasmic vesicle, cytosol, integral to membrane, nucleolus, plasma membrane protein binding Human SPG20 MGI UniProtKB {GO:0005811=GO_REF:0000019, GO:0005515=PMID:20719964, GO:0008219=GO_REF:0000037, GO:0051881=PMID:21559443, GO:0045202=GO_REF:0000019, GO:0005741=PMID:21559443, GO:0034389=GO_REF:0000019, GO:0030514=GO_REF:0000019, GO:0048698=GO_REF:0000019, GO:0050905=GO_REF:0000019, GO:0000910=GO_REF:0000019, GO:0005737=PMID:19580544, GO:0060612=GO_REF:0000019, GO:0031625=PMID:19580544, GO:0051301=PMID:20719964} Q8N0X7 Spartin protein 20120903 {GO:0005811=IEA, GO:0005515=IPI, GO:0008219=IEA, GO:0051881=IMP, GO:0045202=IEA, GO:0005741=IDA, GO:0034389=IEA, GO:0030514=IEA, GO:0048698=IEA, GO:0050905=IEA, GO:0000910=IEA, GO:0005737=IDA, GO:0060612=IEA, GO:0031625=IPI, GO:0051301=IMP} adipose tissue development, cell death, cell division, cytokinesis, lipid particle organization, negative regulation of BMP signaling pathway, negative regulation of collateral sprouting in absence of injury, neuromuscular process, regulation of mitochondrial membrane potential cytoplasm, lipid particle, mitochondrial outer membrane, synapse protein binding, ubiquitin protein ligase binding Human SPG21 HPA UniProtKB {GO:0008219=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0042609=PMID:11113139, GO:0005634=GO_REF:0000052, GO:0030140=PMID:11113139, GO:0050851=PMID:11113139, GO:0010008=GO_REF:0000039, GO:0005829=PMID:11113139} Q9NZD8 Maspardin protein 20111111 {GO:0008219=IEA, GO:0005737=IDA, GO:0042609=IPI, GO:0005634=IDA, GO:0030140=IDA, GO:0050851=IC, GO:0010008=IEA, GO:0005829=IDA} antigen receptor-mediated signaling pathway, cell death cytoplasm, cytosol, endosome membrane, nucleus, trans-Golgi network transport vesicle CD4 receptor binding Human SPG7 PINC UniProtKB {GO:0005515=PMID:14623864, GO:0008219=GO_REF:0000037, GO:0017111=GO_REF:0000002, GO:0031966=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0007399=PMID:9635427, GO:0005739=PMID:9635427, GO:0030163=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0008233=PMID:9635427, GO:0008270=GO_REF:0000002, GO:0008089=GO_REF:0000019, GO:0007005=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0051082=PMID:9635427, GO:0004222=PMID:11549317} Q9UQ90 Paraplegin protein 20030904 {GO:0005515=IPI, GO:0008219=IEA, GO:0017111=IEA, GO:0031966=IEA, GO:0005524=IEA, GO:0007399=TAS, GO:0005739=TAS, GO:0030163=IEA, GO:0006508=IEA, GO:0008233=TAS, GO:0008270=IEA, GO:0008089=IEA, GO:0007005=IEA, GO:0016021=IEA, GO:0051082=TAS, GO:0004222=IDA} anterograde axon cargo transport, cell death, mitochondrion organization, nervous system development, protein catabolic process, proteolysis integral to membrane, mitochondrial membrane, mitochondrion ATP binding, metalloendopeptidase activity, nucleoside-triphosphatase activity, peptidase activity, protein binding, unfolded protein binding, zinc ion binding Human SPHK1 BHF-UCL UniProtKB {GO:0005515=PMID:20838377, GO:0005516=PMID:12393916, GO:0042346=PMID:20577214, GO:0019722=PMID:10947957, GO:0005886=PMID:21075214, GO:0030307=PMID:12441135, GO:0006670=PMID:20577214, GO:0005634=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0048146=PMID:15623571, GO:0008481=PMID:15623571, GO:0007205=GO_REF:0000002, GO:0005829=Reactome:REACT_19412, GO:0035556=PMID:10947957, GO:0005737=PMID:21075214, GO:0051092=PMID:20577214, GO:0006954=GO_REF:0000019, GO:0017050=PMID:20577214, GO:0006457=Reactome:REACT_17004, GO:0045987=PMID:12847068, GO:0004143=GO_REF:0000002, GO:0031398=PMID:20577214, GO:0051721=PMID:21075214, GO:0006665=Reactome:REACT_19323, GO:0043066=PMID:15623571, GO:0030335=PMID:12441135, GO:0001568=GO_REF:0000019, GO:0000287=PMID:10947957, GO:0030148=Reactome:REACT_115810, GO:0010803=PMID:20577214, GO:0003677=PMID:12393916, GO:0005524=PMID:12393916, GO:0045766=PMID:12441135, GO:0007165=PMID:10751414, GO:0045931=PMID:12441135, GO:0007420=GO_REF:0000019, GO:0051084=Reactome:REACT_16952, GO:0032651=GO_REF:0000019, GO:0044267=Reactome:REACT_17015, GO:0046521=PMID:10863092} Q9NYA1 Sphingosine kinase 1 protein 20110301 {GO:0005515=IPI, GO:0005516=IDA, GO:0042346=IMP, GO:0019722=IDA, GO:0005886=IDA, GO:0030307=IDA, GO:0006670=IDA, GO:0005634=IEA, GO:0044281=TAS, GO:0048146=IDA, GO:0008481=IDA, GO:0007205=IEA, GO:0005829=TAS, GO:0035556=TAS, GO:0005737=IDA, GO:0051092=IMP, GO:0006954=IEA, GO:0017050=IDA, GO:0006457=TAS, GO:0045987=IDA, GO:0004143=IEA, GO:0031398=IDA, GO:0051721=IPI, GO:0006665=TAS, GO:0043066=IDA, GO:0030335=IDA, GO:0001568=IEA, GO:0000287=IDA, GO:0030148=TAS, GO:0010803=IDA, GO:0003677=IDA, GO:0005524=IDA, GO:0045766=IDA, GO:0007165=TAS, GO:0045931=IDA, GO:0007420=IEA, GO:0051084=TAS, GO:0032651=IEA, GO:0044267=TAS, GO:0046521=NAS} 'de novo' posttranslational protein folding, blood vessel development, brain development, calcium-mediated signaling, cellular protein metabolic process, inflammatory response, intracellular signal transduction, negative regulation of apoptotic process, positive regulation of NF-kappaB import into nucleus, positive regulation of NF-kappaB transcription factor activity, positive regulation of angiogenesis, positive regulation of cell growth, positive regulation of cell migration, positive regulation of fibroblast proliferation, positive regulation of mitotic cell cycle, positive regulation of protein ubiquitination, positive regulation of smooth muscle contraction, protein folding, protein kinase C-activating G-protein coupled receptor signaling pathway, regulation of interleukin-1 beta production, regulation of tumor necrosis factor-mediated signaling pathway, signal transduction, small molecule metabolic process, sphingoid catabolic process, sphingolipid biosynthetic process, sphingolipid metabolic process, sphingosine metabolic process cytoplasm, cytosol, nucleus, plasma membrane ATP binding, D-erythro-sphingosine kinase activity, DNA binding, calmodulin binding, diacylglycerol kinase activity, magnesium ion binding, protein binding, protein phosphatase 2A binding, sphinganine kinase activity Human SPHK2 Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0005515=PMID:11777919, GO:0008284=GO_REF:0000019, GO:0043066=PMID:10751414, GO:0001568=GO_REF:0000019, GO:0008283=PMID:10751414, GO:0030148=Reactome:REACT_115810, GO:0006670=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0005765=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0007205=GO_REF:0000002, GO:0008481=PMID:10751414, GO:0005829=Reactome:REACT_19412, GO:0017050=GO_REF:0000019, GO:0016020=PMID:10751414, GO:0007420=GO_REF:0000019, GO:0004143=GO_REF:0000002, GO:0017016=PMID:12391145, GO:0006669=PMID:10751414} Q9NRA0 Sphingosine kinase 2 protein 20130301 {GO:0006665=TAS, GO:0005515=IPI, GO:0008284=IEA, GO:0043066=NAS, GO:0001568=IEA, GO:0008283=NAS, GO:0030148=TAS, GO:0006670=IEA, GO:0044281=TAS, GO:0005765=IEA, GO:0005524=IEA, GO:0007205=IEA, GO:0008481=NAS, GO:0005829=TAS, GO:0017050=IEA, GO:0016020=IDA, GO:0007420=IEA, GO:0004143=IEA, GO:0017016=NAS, GO:0006669=NAS} blood vessel development, brain development, cell proliferation, negative regulation of apoptotic process, positive regulation of cell proliferation, protein kinase C-activating G-protein coupled receptor signaling pathway, small molecule metabolic process, sphinganine-1-phosphate biosynthetic process, sphingolipid biosynthetic process, sphingolipid metabolic process, sphingosine metabolic process cytosol, lysosomal membrane, membrane ATP binding, D-erythro-sphingosine kinase activity, Ras GTPase binding, diacylglycerol kinase activity, protein binding, sphinganine kinase activity Human SPHKAP UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0030018=GO_REF:0000019, GO:0051018=PMID:20394097} Q2M3C7 A-kinase anchor protein SPHKAP protein 20110815 {GO:0005739=IEA, GO:0030018=IEA, GO:0051018=IDA} Z disc, mitochondrion protein kinase A binding Human SPI1 BHF-UCL UniProtKB {GO:0005515=PMID:21575865, GO:0000790=PMID:15304486, GO:0090241=PMID:20139074, GO:0003700=PMID:12833137, GO:0051525=GO_REF:0000024, GO:0003705=GO_REF:0000024, GO:0003723=GO_REF:0000037, GO:0044027=PMID:20139074, GO:0045944=GO_REF:0000024, GO:0001085=GO_REF:0000024, GO:0045347=GO_REF:0000019, GO:0030098=GO_REF:0000019, GO:0030225=GO_REF:0000019, GO:0043011=GO_REF:0000019, GO:0030851=GO_REF:0000019, GO:0035019=GO_REF:0000019, GO:0001944=GO_REF:0000019, GO:0002320=GO_REF:0000019, GO:0060033=GO_REF:0000019, GO:0001205=GO_REF:0000019, GO:0001047=PMID:20139074, GO:0006917=GO_REF:0000019, GO:0000122=PMID:10867017, GO:0043966=PMID:20139074, GO:0045814=PMID:20139074, GO:0030218=GO_REF:0000019, GO:0045646=PMID:12833137, GO:0000980=GO_REF:0000024, GO:0045893=PMID:12833137, GO:0045892=PMID:20139074} P17947 Transcription factor PU.1 protein 20111206 {GO:0005515=IPI, GO:0000790=IDA, GO:0090241=IMP, GO:0003700=IDA, GO:0051525=ISS, GO:0003705=ISS, GO:0003723=IEA, GO:0044027=IDA, GO:0045944=ISS, GO:0001085=ISS, GO:0045347=IEA, GO:0030098=IEA, GO:0030225=IEA, GO:0043011=IEA, GO:0030851=IEA, GO:0035019=IEA, GO:0001944=IEA, GO:0002320=IEA, GO:0060033=IEA, GO:0001205=IEA, GO:0001047=IDA, GO:0006917=IEA, GO:0000122=TAS, GO:0043966=IMP, GO:0045814=IDA, GO:0030218=IEA, GO:0045646=IMP, GO:0000980=ISS, GO:0045893=IDA, GO:0045892=IDA} anatomical structure regression, erythrocyte differentiation, granulocyte differentiation, histone H3 acetylation, hypermethylation of CpG island, induction of apoptosis, lymphocyte differentiation, lymphoid progenitor cell differentiation, macrophage differentiation, myeloid dendritic cell differentiation, negative regulation of MHC class II biosynthetic process, negative regulation of gene expression, epigenetic, negative regulation of histone H4 acetylation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of erythrocyte differentiation, somatic stem cell maintenance, vasculature development nuclear chromatin NFAT protein binding, RNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II transcription factor binding, core promoter binding, protein binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:P17433 SPIB HPA UniProtKB {GO:0043565=GO_REF:0000002, GO:0006260=GO_REF:0000002, GO:0005737=PMID:8670269, GO:0003700=GO_REF:0000002, GO:0006357=PMID:1406622, GO:0000166=GO_REF:0000002, GO:0003887=GO_REF:0000002, GO:0015630=GO_REF:0000052, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q01892 Transcription factor Spi-B protein 20090616 {GO:0043565=IEA, GO:0006260=IEA, GO:0005737=TAS, GO:0003700=IEA, GO:0006357=TAS, GO:0000166=IEA, GO:0003887=IEA, GO:0015630=IDA, GO:0005634=IEA, GO:0006351=IEA} DNA replication, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, microtubule cytoskeleton, nucleus DNA-directed DNA polymerase activity, nucleotide binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human SPIC UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0045944=GO_REF:0000019, GO:0001824=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q8N5J4 Transcription factor Spi-C protein 20130413 {GO:0043565=IEA, GO:0003700=IEA, GO:0045944=IEA, GO:0001824=IEA, GO:0005634=IEA, GO:0006351=IEA} blastocyst development, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0191 SPICE1 UniProtKB UniProtKB {GO:0005813=PMID:21399614, GO:0005814=PMID:20736305, GO:0005819=PMID:20736305, GO:0090307=PMID:20736305, GO:0046599=PMID:20736305, GO:0051310=PMID:20736305, GO:0051301=GO_REF:0000037} Q8N0Z3 Spindle and centriole-associated protein 1 protein 20110517 {GO:0005813=IDA, GO:0005814=IDA, GO:0005819=IDA, GO:0090307=IMP, GO:0046599=IMP, GO:0051310=IMP, GO:0051301=IEA} cell division, metaphase plate congression, regulation of centriole replication, spindle assembly involved in mitosis centriole, centrosome, spindle Human SPIN1 LIFEdb UniProtKB {GO:0007049=GO_REF:0000037, GO:0007276=GO_REF:0000002, GO:0005819=GO_REF:0000019, GO:0005634=GO_REF:0000054, GO:0007275=GO_REF:0000037, GO:0035064=PMID:21029866, GO:0003677=GO_REF:0000037} Q9Y657 Spindlin-1 protein 20100607 {GO:0007049=IEA, GO:0007276=IEA, GO:0005819=IEA, GO:0005634=IDA, GO:0007275=IEA, GO:0035064=IDA, GO:0003677=IEA} cell cycle, gamete generation, multicellular organismal development nucleus, spindle DNA binding, methylated histone residue binding Human SPIN2A UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0007049=GO_REF:0000037, GO:0007276=GO_REF:0000002, GO:0005575=GO_REF:0000015} Q99865 Spindlin-2A protein 20061026 {GO:0003674=ND, GO:0007049=IEA, GO:0007276=IEA, GO:0005575=ND} cell cycle, gamete generation cellular_component molecular_function Human SPIN2B UniProtKB UniProtKB {GO:0007049=GO_REF:0000037, GO:0007276=GO_REF:0000002, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000039} Q9BPZ2 Spindlin-2B protein 20130413 {GO:0007049=IEA, GO:0007276=IEA, GO:0006915=IEA, GO:0005634=IEA} apoptotic process, cell cycle, gamete generation nucleus Human UniProtKB-SubCell:SL-0191 SPIN3 InterPro UniProtKB {GO:0007276=GO_REF:0000002} Q5JUX0 Spindlin-3 protein 20130413 {GO:0007276=IEA} gamete generation Human InterPro:IPR003671 SPIN4 InterPro UniProtKB {GO:0007276=GO_REF:0000002} Q56A73 Spindlin-4 protein 20130413 {GO:0007276=IEA} gamete generation Human InterPro:IPR003671 SPINK1 GOC UniProtKB {GO:0010951=PMID:7142173, GO:0005515=PMID:14507909, GO:0004866=PMID:7142173, GO:0004867=GO_REF:0000037, GO:0005576=GO_REF:0000039} P00995 Pancreatic secretory trypsin inhibitor protein 20130413 {GO:0010951=TAS, GO:0005515=IPI, GO:0004866=TAS, GO:0004867=IEA, GO:0005576=IEA} negative regulation of endopeptidase activity extracellular region endopeptidase inhibitor activity, protein binding, serine-type endopeptidase inhibitor activity Human SPINK13 UniProtKB UniProtKB {GO:0004867=GO_REF:0000037, GO:0005576=GO_REF:0000039} Q1W4C9 Serine protease inhibitor Kazal-type 13 protein 20130413 {GO:0004867=IEA, GO:0005576=IEA} extracellular region serine-type endopeptidase inhibitor activity Human UniProtKB-SubCell:SL-0243 SPINK5 UniProtKB UniProtKB {GO:0035315=PMID:12915442, GO:0048471=PMID:15680911, GO:0042640=PMID:12915442, GO:0004867=PMID:15680911, GO:0005783=PMID:15680911, GO:0005576=PMID:15680911, GO:0030155=GO_REF:0000019, GO:0009913=PMID:12915442, GO:0045861=GO_REF:0000019, GO:0005829=PMID:15680911, GO:0005737=PMID:12915442, GO:0050777=PMID:12915442, GO:0030198=PMID:15680911, GO:0030855=PMID:12915442, GO:0016525=PMID:15680911, GO:0005789=PMID:15680911, GO:0045580=PMID:12915442, GO:0005938=PMID:12915442} Q9NQ38 Serine protease inhibitor Kazal-type 5 protein 20060111 {GO:0035315=TAS, GO:0048471=IDA, GO:0042640=TAS, GO:0004867=IDA, GO:0005783=IDA, GO:0005576=IDA, GO:0030155=IEA, GO:0009913=IDA, GO:0045861=IEA, GO:0005829=IDA, GO:0005737=IDA, GO:0050777=TAS, GO:0030198=TAS, GO:0030855=TAS, GO:0016525=TAS, GO:0005789=IDA, GO:0045580=TAS, GO:0005938=IDA} anagen, epidermal cell differentiation, epithelial cell differentiation, extracellular matrix organization, hair cell differentiation, negative regulation of angiogenesis, negative regulation of immune response, negative regulation of proteolysis, regulation of T cell differentiation, regulation of cell adhesion cell cortex, cytoplasm, cytosol, endoplasmic reticulum, endoplasmic reticulum membrane, extracellular region, perinuclear region of cytoplasm serine-type endopeptidase inhibitor activity Human SPINK6 UniProtKB UniProtKB {GO:0004867=GO_REF:0000037, GO:0005576=GO_REF:0000039} Q6UWN8 Serine protease inhibitor Kazal-type 6 protein 20130413 {GO:0004867=IEA, GO:0005576=IEA} extracellular region serine-type endopeptidase inhibitor activity Human UniProtKB-SubCell:SL-0243 SPINK7 IntAct UniProtKB {GO:0005515=PMID:12970870, GO:0004867=GO_REF:0000037, GO:0005576=GO_REF:0000039} P58062 Serine protease inhibitor Kazal-type 7 protein 20130415 {GO:0005515=IPI, GO:0004867=IEA, GO:0005576=IEA} extracellular region protein binding, serine-type endopeptidase inhibitor activity Human UniProtKB:Q8IZW4 SPINT1 PINC UniProtKB {GO:0060674=GO_REF:0000019, GO:0016020=PMID:9045658, GO:0030198=GO_REF:0000019, GO:0004867=GO_REF:0000037, GO:0060670=GO_REF:0000019, GO:0005576=GO_REF:0000039} O43278 Kunitz-type protease inhibitor 1 protein 20030904 {GO:0060674=IEA, GO:0016020=TAS, GO:0030198=IEA, GO:0004867=IEA, GO:0060670=IEA, GO:0005576=IEA} branching involved in labyrinthine layer morphogenesis, extracellular matrix organization, placenta blood vessel development extracellular region, membrane serine-type endopeptidase inhibitor activity Human SPINT2 GOC UniProtKB {GO:0010951=PMID:9115294, GO:0005737=PMID:11606055, GO:0004866=PMID:9115294, GO:0004867=GO_REF:0000037, GO:0006928=PMID:9434156, GO:0005576=PMID:9346890, GO:0016021=GO_REF:0000037} O43291 Kunitz-type protease inhibitor 2 protein 20130413 {GO:0010951=TAS, GO:0005737=IDA, GO:0004866=TAS, GO:0004867=IEA, GO:0006928=TAS, GO:0005576=TAS, GO:0016021=IEA} cellular component movement, negative regulation of endopeptidase activity cytoplasm, extracellular region, integral to membrane endopeptidase inhibitor activity, serine-type endopeptidase inhibitor activity Human SPINT3 UniProtKB UniProtKB {GO:0004867=GO_REF:0000037, GO:0005576=GO_REF:0000039} P49223 Kunitz-type protease inhibitor 3 protein 20130413 {GO:0004867=IEA, GO:0005576=IEA} extracellular region serine-type endopeptidase inhibitor activity Human UniProtKB-SubCell:SL-0243 SPIRE1 UniProtKB UniProtKB {GO:0048471=GO_REF:0000039, GO:0030036=PMID:21620703, GO:0005794=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0070649=GO_REF:0000024, GO:0003779=GO_REF:0000037, GO:0046907=GO_REF:0000024, GO:0015031=GO_REF:0000037, GO:0032154=GO_REF:0000024, GO:0036089=GO_REF:0000024, GO:0051295=PMID:21620703, GO:0040038=GO_REF:0000024, GO:0048193=GO_REF:0000019, GO:0005856=GO_REF:0000039, GO:0016192=GO_REF:0000024, GO:0005938=GO_REF:0000024, GO:0030659=GO_REF:0000024} Q08AE8 Protein spire homolog 1 protein 20130204 {GO:0048471=IEA, GO:0030036=IMP, GO:0005794=IEA, GO:0005886=IEA, GO:0070649=ISS, GO:0003779=IEA, GO:0046907=ISS, GO:0015031=IEA, GO:0032154=ISS, GO:0036089=ISS, GO:0051295=IMP, GO:0040038=ISS, GO:0048193=IEA, GO:0005856=IEA, GO:0016192=ISS, GO:0005938=ISS, GO:0030659=ISS} Golgi vesicle transport, actin cytoskeleton organization, cleavage furrow formation, establishment of meiotic spindle localization, formin-nucleated actin cable assembly, intracellular transport, polar body extrusion after meiotic divisions, protein transport, vesicle-mediated transport Golgi apparatus, cell cortex, cleavage furrow, cytoplasmic vesicle membrane, cytoskeleton, perinuclear region of cytoplasm, plasma membrane actin binding Human SPN Reactome UniProtKB {GO:0050688=GO_REF:0000019, GO:0005886=Reactome:REACT_16931, GO:0031295=GO_REF:0000019, GO:0050900=Reactome:REACT_12051, GO:0005615=PMID:10899905, GO:0042130=GO_REF:0000019, GO:0006955=PMID:2023632, GO:0006935=PMID:10753822, GO:0042102=GO_REF:0000019, GO:0001562=GO_REF:0000019, GO:0042742=PMID:10899905, GO:0009986=PMID:20605918, GO:0042535=PMID:10899905, GO:0001808=GO_REF:0000019, GO:0005604=GO_REF:0000019, GO:0051635=PMID:10899905, GO:0007165=PMID:2023632, GO:0007162=GO_REF:0000019, GO:0006968=PMID:1683685, GO:0007163=PMID:10753822, GO:0007596=Reactome:REACT_604, GO:0005887=GO_REF:0000019, GO:0045060=GO_REF:0000019, GO:0001931=GO_REF:0000019, GO:0007166=GO_REF:0000019, GO:0009897=GO_REF:0000019, GO:0004888=PMID:1683685} P16150 Leukosialin protein 20071128 {GO:0050688=IEA, GO:0005886=TAS, GO:0031295=IEA, GO:0050900=TAS, GO:0005615=IDA, GO:0042130=IEA, GO:0006955=TAS, GO:0006935=TAS, GO:0042102=IEA, GO:0001562=IEA, GO:0042742=IDA, GO:0009986=IDA, GO:0042535=IDA, GO:0001808=IEA, GO:0005604=IEA, GO:0051635=IDA, GO:0007165=TAS, GO:0007162=IEA, GO:0006968=TAS, GO:0007163=TAS, GO:0007596=TAS, GO:0005887=IEA, GO:0045060=IEA, GO:0001931=IEA, GO:0007166=IEA, GO:0009897=IEA, GO:0004888=TAS} T cell costimulation, blood coagulation, cell surface receptor signaling pathway, cellular defense response, chemotaxis, defense response to bacterium, establishment or maintenance of cell polarity, immune response, leukocyte migration, negative regulation of T cell proliferation, negative regulation of cell adhesion, negative regulation of type IV hypersensitivity, negative thymic T cell selection, positive regulation of T cell proliferation, positive regulation of tumor necrosis factor biosynthetic process, regulation of defense response to virus, response to protozoan, signal transduction basement membrane, cell surface, external side of plasma membrane, extracellular space, integral to plasma membrane, plasma membrane, uropod bacterial cell surface binding, transmembrane signaling receptor activity Human SPNS1 UniProtKB UniProtKB {GO:0006869=GO_REF:0000037, GO:0005743=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0055085=GO_REF:0000002} Q9H2V7 Protein spinster homolog 1 protein 20130413 {GO:0006869=IEA, GO:0005743=IEA, GO:0016021=IEA, GO:0055085=IEA} lipid transport, transmembrane transport integral to membrane, mitochondrial inner membrane Human UniProtKB-SubCell:SL-0168 SPOCD1 UniProtKB UniProtKB {GO:0010923=PMID:19389623, GO:0006351=GO_REF:0000002} Q6ZMY3 SPOC domain-containing protein 1 protein 20111103 {GO:0010923=IDA, GO:0006351=IEA} negative regulation of phosphatase activity, transcription, DNA-dependent Human SPOCK1 UniProtKB UniProtKB {GO:0031594=GO_REF:0000024, GO:0004867=PMID:14511383, GO:0005509=PMID:9323035, GO:0010812=PMID:12853036, GO:0005578=GO_REF:0000039, GO:0014069=PMID:9181134, GO:0021953=GO_REF:0000024, GO:0001558=PMID:8389704, GO:0005615=PMID:14511383, GO:0007399=PMID:9181134, GO:0010951=PMID:14511383, GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000024, GO:0016528=GO_REF:0000024, GO:0033268=GO_REF:0000024, GO:0008191=PMID:11751414, GO:0010977=PMID:12853036, GO:0001764=GO_REF:0000024, GO:0007155=PMID:8389704, GO:0022008=GO_REF:0000024} Q08629 Testican-1 protein 20111104 {GO:0031594=ISS, GO:0004867=NAS, GO:0005509=IDA, GO:0010812=IDA, GO:0005578=IEA, GO:0014069=NAS, GO:0021953=ISS, GO:0001558=NAS, GO:0005615=IDA, GO:0007399=NAS, GO:0010951=IDA, GO:0007165=IEA, GO:0005737=ISS, GO:0016528=ISS, GO:0033268=ISS, GO:0008191=IDA, GO:0010977=IDA, GO:0001764=ISS, GO:0007155=NAS, GO:0022008=ISS} cell adhesion, central nervous system neuron differentiation, negative regulation of cell-substrate adhesion, negative regulation of endopeptidase activity, negative regulation of neuron projection development, nervous system development, neurogenesis, neuron migration, regulation of cell growth, signal transduction cytoplasm, extracellular space, neuromuscular junction, node of Ranvier, postsynaptic density, proteinaceous extracellular matrix, sarcoplasm calcium ion binding, metalloendopeptidase inhibitor activity, serine-type endopeptidase inhibitor activity Human UniProtKB:Q62288 SPOCK2 UniProtKB UniProtKB {GO:0019800=GO_REF:0000019, GO:0007165=GO_REF:0000002, GO:0030198=PMID:10386950, GO:0010811=GO_REF:0000019, GO:0005509=PMID:10386950, GO:0050840=GO_REF:0000019, GO:0005578=PMID:10386950, GO:0045595=PMID:10386950, GO:0005539=GO_REF:0000019, GO:0007416=PMID:10386950} Q92563 Testican-2 protein 20021105 {GO:0019800=IEA, GO:0007165=IEA, GO:0030198=NAS, GO:0010811=IEA, GO:0005509=IDA, GO:0050840=IEA, GO:0005578=NAS, GO:0045595=NAS, GO:0005539=IEA, GO:0007416=NAS} extracellular matrix organization, peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan, positive regulation of cell-substrate adhesion, regulation of cell differentiation, signal transduction, synapse assembly proteinaceous extracellular matrix calcium ion binding, extracellular matrix binding, glycosaminoglycan binding Human SPOCK3 UniProtKB UniProtKB {GO:0019800=GO_REF:0000019, GO:0007165=GO_REF:0000002, GO:0008191=GO_REF:0000037, GO:0005509=GO_REF:0000002, GO:0005578=GO_REF:0000039, GO:0005539=GO_REF:0000019} Q9BQ16 Testican-3 protein 20130413 {GO:0019800=IEA, GO:0007165=IEA, GO:0008191=IEA, GO:0005509=IEA, GO:0005578=IEA, GO:0005539=IEA} peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan, signal transduction proteinaceous extracellular matrix calcium ion binding, glycosaminoglycan binding, metalloendopeptidase inhibitor activity Human UniProtKB-SubCell:SL-0111 SPON1 BHF-UCL UniProtKB {GO:0031012=PMID:22261194, GO:0005515=PMID:14983046, GO:0005578=GO_REF:0000039, GO:0007155=GO_REF:0000037} Q9HCB6 Spondin-1 protein 20120228 {GO:0031012=ISS, GO:0005515=IPI, GO:0005578=IEA, GO:0007155=IEA} cell adhesion extracellular matrix, proteinaceous extracellular matrix protein binding colocalizes_with Human UniProtKB:F1S981 SPOP IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0016567=GO_REF:0000041, GO:0016607=GO_REF:0000039, GO:0031463=PMID:22085717, GO:0043161=PMID:22085717, GO:0005634=PMID:22085717, GO:0031625=PMID:11279055} O43791 Speckle-type POZ protein protein 20130415 {GO:0005515=IPI, GO:0016567=IEA, GO:0016607=IEA, GO:0031463=IDA, GO:0043161=IMP, GO:0005634=IDA, GO:0031625=IPI} proteasomal ubiquitin-dependent protein catabolic process, protein ubiquitination Cul3-RING ubiquitin ligase complex, nuclear speck, nucleus protein binding, ubiquitin protein ligase binding Human UniProtKB:Q9UER7 SPP1 BHF-UCL UniProtKB {GO:0048471=GO_REF:0000019, GO:0007566=PMID:16720713, GO:0010811=GO_REF:0000019, GO:0030593=GO_REF:0000019, GO:0031988=GO_REF:0000019, GO:0050840=GO_REF:0000019, GO:0045177=GO_REF:0000019, GO:0033280=PMID:16720713, GO:0005576=Reactome:REACT_16880, GO:0042995=GO_REF:0000019, GO:0048545=GO_REF:0000019, GO:0005125=GO_REF:0000037, GO:0031214=GO_REF:0000037, GO:0005615=PMID:15516325, GO:0001649=GO_REF:0000019, GO:0048685=GO_REF:0000019, GO:0046697=PMID:16720713, GO:0006954=GO_REF:0000019, GO:0001503=GO_REF:0000002, GO:0045780=GO_REF:0000019, GO:0007155=GO_REF:0000037} P10451 Osteopontin protein 20120501 {GO:0048471=IEA, GO:0007566=TAS, GO:0010811=IEA, GO:0030593=IEA, GO:0031988=IEA, GO:0050840=IEA, GO:0045177=IEA, GO:0033280=IDA, GO:0005576=TAS, GO:0042995=IEA, GO:0048545=IEA, GO:0005125=IEA, GO:0031214=IEA, GO:0005615=IDA, GO:0001649=IEA, GO:0048685=IEA, GO:0046697=TAS, GO:0006954=IEA, GO:0001503=IEA, GO:0045780=IEA, GO:0007155=IEA} biomineral tissue development, cell adhesion, decidualization, embryo implantation, inflammatory response, negative regulation of collateral sprouting of intact axon in response to injury, neutrophil chemotaxis, ossification, osteoblast differentiation, positive regulation of bone resorption, positive regulation of cell-substrate adhesion, response to steroid hormone stimulus, response to vitamin D apical part of cell, cell projection, extracellular region, extracellular space, membrane-bounded vesicle, perinuclear region of cytoplasm cytokine activity, extracellular matrix binding Human SPPL2A UniProtKB UniProtKB {GO:0005515=PMID:17965014, GO:0005886=GO_REF:0000039, GO:0031293=PMID:16829951, GO:0071458=PMID:15385547, GO:0005765=GO_REF:0000039, GO:0042803=PMID:15385547, GO:0030660=PMID:17965014, GO:0031902=GO_REF:0000039, GO:0050776=PMID:16829952, GO:0071556=PMID:15385547, GO:0004190=GO_REF:0000002, GO:0016021=GO_REF:0000002, GO:0006509=PMID:16829951} Q8TCT8 Signal peptide peptidase-like 2A protein 20120301 {GO:0005515=IPI, GO:0005886=IEA, GO:0031293=IDA, GO:0071458=IDA, GO:0005765=IEA, GO:0042803=IDA, GO:0030660=IDA, GO:0031902=IEA, GO:0050776=IMP, GO:0071556=IDA, GO:0004190=IEA, GO:0016021=IEA, GO:0006509=IDA} membrane protein ectodomain proteolysis, membrane protein intracellular domain proteolysis, regulation of immune response Golgi-associated vesicle membrane, integral to cytosolic side of endoplasmic reticulum membrane, integral to lumenal side of endoplasmic reticulum membrane, integral to membrane, late endosome membrane, lysosomal membrane, plasma membrane aspartic-type endopeptidase activity, protein binding, protein homodimerization activity Human SPPL3 UniProtKB UniProtKB {GO:0005791=PMID:15998642, GO:0030660=PMID:16829952, GO:0071556=PMID:15385547, GO:0071458=PMID:15385547, GO:0006509=PMID:16829952, GO:0016021=GO_REF:0000002, GO:0004190=GO_REF:0000002, GO:0042500=PMID:16873890, GO:0042803=PMID:15385547} Q8TCT6 Signal peptide peptidase-like 3 protein 20120302 {GO:0005791=IDA, GO:0030660=IDA, GO:0071556=IDA, GO:0071458=IDA, GO:0006509=IMP, GO:0016021=IEA, GO:0004190=IEA, GO:0042500=IMP, GO:0042803=IDA} membrane protein ectodomain proteolysis Golgi-associated vesicle membrane, integral to cytosolic side of endoplasmic reticulum membrane, integral to lumenal side of endoplasmic reticulum membrane, integral to membrane, rough endoplasmic reticulum aspartic endopeptidase activity, intramembrane cleaving, aspartic-type endopeptidase activity, protein homodimerization activity Human SPR HPA UniProtKB {GO:0050661=PMID:1883349, GO:0004757=Reactome:REACT_111234, GO:0006729=PMID:1883349, GO:0050999=Reactome:REACT_12389, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0006809=PMID:15197144, GO:0005829=Reactome:REACT_111234, GO:0004033=PMID:1883349, GO:0005737=GO_REF:0000052, GO:0046209=Reactome:REACT_12508, GO:0055114=PMID:1883349} P35270 Sepiapterin reductase protein 20111111 {GO:0050661=TAS, GO:0004757=TAS, GO:0006729=TAS, GO:0050999=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0006809=IDA, GO:0005829=TAS, GO:0004033=TAS, GO:0005737=IDA, GO:0046209=TAS, GO:0055114=TAS} nitric oxide biosynthetic process, nitric oxide metabolic process, oxidation-reduction process, regulation of nitric-oxide synthase activity, small molecule metabolic process, tetrahydrobiopterin biosynthetic process cytoplasm, cytosol, nucleolus, nucleus NADP binding, aldo-keto reductase (NADP) activity, sepiapterin reductase activity Human SPRED1 HPA UniProtKB {GO:0005515=PMID:22321011, GO:0005886=GO_REF:0000052, GO:0019901=PMID:20736167, GO:0019902=PMID:19389623, GO:0005730=GO_REF:0000052, GO:0007275=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0010801=PMID:20736167, GO:0090311=GO_REF:0000019, GO:0030291=PMID:20736167, GO:0000188=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0005901=GO_REF:0000039, GO:0010923=PMID:19389623, GO:0043517=PMID:20736167, GO:0005173=GO_REF:0000024} Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 protein 20110516 {GO:0005515=IPI, GO:0005886=IDA, GO:0019901=IPI, GO:0019902=IDA, GO:0005730=IDA, GO:0007275=IEA, GO:0005634=IDA, GO:0010801=IMP, GO:0090311=IEA, GO:0030291=ISS, GO:0000188=ISS, GO:0005737=IDA, GO:0005901=IEA, GO:0010923=IDA, GO:0043517=ISS, GO:0005173=ISS} inactivation of MAPK activity, multicellular organismal development, negative regulation of peptidyl-threonine phosphorylation, negative regulation of phosphatase activity, positive regulation of DNA damage response, signal transduction by p53 class mediator, regulation of protein deacetylation caveola, cytoplasm, nucleolus, nucleus, plasma membrane phosphatase binding, protein binding, protein kinase binding, protein serine/threonine kinase inhibitor activity, stem cell factor receptor binding Human SPRED2 BHF-UCL UniProtKB {GO:0005515=PMID:19822672, GO:0005886=GO_REF:0000019, GO:0019901=PMID:20736167, GO:0007275=GO_REF:0000002, GO:0031410=GO_REF:0000019, GO:0009966=GO_REF:0000002, GO:0010801=PMID:20736167, GO:0090311=GO_REF:0000019, GO:0030291=PMID:20736167, GO:0000188=GO_REF:0000024, GO:0016020=GO_REF:0000002, GO:0043517=PMID:20736167, GO:0005173=GO_REF:0000024, GO:0030658=GO_REF:0000039} Q7Z698 Sprouty-related, EVH1 domain-containing protein 2 protein 20120312 {GO:0005515=IPI, GO:0005886=IEA, GO:0019901=IPI, GO:0007275=IEA, GO:0031410=IEA, GO:0009966=IEA, GO:0010801=IMP, GO:0090311=IEA, GO:0030291=ISS, GO:0000188=ISS, GO:0016020=IEA, GO:0043517=ISS, GO:0005173=ISS, GO:0030658=IEA} inactivation of MAPK activity, multicellular organismal development, negative regulation of peptidyl-threonine phosphorylation, positive regulation of DNA damage response, signal transduction by p53 class mediator, regulation of protein deacetylation, regulation of signal transduction cytoplasmic vesicle, membrane, plasma membrane, transport vesicle membrane protein binding, protein kinase binding, protein serine/threonine kinase inhibitor activity, stem cell factor receptor binding Human UniProtKB:Q924S7 SPRED3 ENSEMBL UniProtKB {GO:0000188=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0007275=GO_REF:0000002, GO:0009966=GO_REF:0000002} Q2MJR0 Sprouty-related, EVH1 domain-containing protein 3 protein 20130413 {GO:0000188=IEA, GO:0005886=IEA, GO:0016020=IEA, GO:0007275=IEA, GO:0009966=IEA} inactivation of MAPK activity, multicellular organismal development, regulation of signal transduction membrane, plasma membrane Human Ensembl:ENSMUSP00000046216 SPRN UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0031225=GO_REF:0000037} Q5BIV9 Shadow of prion protein protein 20130413 {GO:0005886=IEA, GO:0031225=IEA} anchored to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 SPRR1A PINC UniProtKB {GO:0005515=PMID:10066784, GO:0005737=GO_REF:0000039, GO:0018149=PMID:10908733, GO:0008544=PMID:8325635, GO:0005198=PMID:10908733, GO:0030216=PMID:10908733, GO:0031424=GO_REF:0000037, GO:0030674=PMID:10908733, GO:0001533=PMID:10908733} P35321 Cornifin-A protein 20030904 {GO:0005515=IPI, GO:0005737=IEA, GO:0018149=IDA, GO:0008544=TAS, GO:0005198=IDA, GO:0030216=IDA, GO:0031424=IEA, GO:0030674=IDA, GO:0001533=IDA} epidermis development, keratinization, keratinocyte differentiation, peptide cross-linking cornified envelope, cytoplasm protein binding, protein binding, bridging, structural molecule activity Human SPRR1B PINC UniProtKB {GO:0005737=GO_REF:0000039, GO:0018149=PMID:10908733, GO:0008544=PMID:1627333, GO:0005198=PMID:10908733, GO:0030216=PMID:10908733, GO:0031424=GO_REF:0000037, GO:0030674=PMID:10908733, GO:0001533=PMID:10908733} P22528 Cornifin-B protein 20030904 {GO:0005737=IEA, GO:0018149=IDA, GO:0008544=TAS, GO:0005198=IDA, GO:0030216=IDA, GO:0031424=IEA, GO:0030674=IDA, GO:0001533=IDA} epidermis development, keratinization, keratinocyte differentiation, peptide cross-linking cornified envelope, cytoplasm protein binding, bridging, structural molecule activity Human SPRR2A UniProtKB UniProtKB {GO:0005737=PMID:16639001, GO:0008544=PMID:8325635, GO:0030216=PMID:8325635, GO:0031424=GO_REF:0000037, GO:0001533=PMID:8325635} P35326 Small proline-rich protein 2A protein 20060607 {GO:0005737=IDA, GO:0008544=NAS, GO:0030216=NAS, GO:0031424=IEA, GO:0001533=NAS} epidermis development, keratinization, keratinocyte differentiation cornified envelope, cytoplasm Human SPRR2B UniProtKB UniProtKB {GO:0005737=GO_REF:0000029, GO:0008544=PMID:8325635, GO:0030216=PMID:8325635, GO:0031424=GO_REF:0000037, GO:0001533=PMID:8325635} P35325 Small proline-rich protein 2B protein 20060314 {GO:0005737=NAS, GO:0008544=NAS, GO:0030216=NAS, GO:0031424=IEA, GO:0001533=NAS} epidermis development, keratinization, keratinocyte differentiation cornified envelope, cytoplasm Human SPRR2D UniProtKB UniProtKB {GO:0005737=PMID:16639001, GO:0008544=PMID:8325635, GO:0030216=GO_REF:0000029, GO:0031424=GO_REF:0000037, GO:0001533=GO_REF:0000029} P22532 Small proline-rich protein 2D protein 20060607 {GO:0005737=IDA, GO:0008544=NAS, GO:0030216=NAS, GO:0031424=IEA, GO:0001533=NAS} epidermis development, keratinization, keratinocyte differentiation cornified envelope, cytoplasm Human SPRR2E UniProtKB UniProtKB {GO:0005515=PMID:9722562, GO:0005737=PMID:3133554, GO:0008544=PMID:8325635, GO:0005198=PMID:3133554, GO:0030216=GO_REF:0000029, GO:0031424=GO_REF:0000037, GO:0001533=GO_REF:0000029} P22531 Small proline-rich protein 2E protein 20060314 {GO:0005515=IPI, GO:0005737=IDA, GO:0008544=NAS, GO:0005198=TAS, GO:0030216=NAS, GO:0031424=IEA, GO:0001533=NAS} epidermis development, keratinization, keratinocyte differentiation cornified envelope, cytoplasm protein binding, structural molecule activity Human SPRR2G UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0008544=PMID:8325635, GO:0030216=PMID:8325635, GO:0031424=GO_REF:0000037, GO:0001533=PMID:8325635} Q9BYE4 Small proline-rich protein 2G protein 20060314 {GO:0005737=IEA, GO:0008544=NAS, GO:0030216=NAS, GO:0031424=IEA, GO:0001533=NAS} epidermis development, keratinization, keratinocyte differentiation cornified envelope, cytoplasm Human SPRR3 UniProtKB UniProtKB {GO:0005515=PMID:10510474, GO:0005737=GO_REF:0000039, GO:0018149=GO_REF:0000002, GO:0008544=PMID:8325635, GO:0005198=PMID:9889002, GO:0030216=PMID:8325635, GO:0042060=PMID:10510474, GO:0031424=GO_REF:0000037} Q9UBC9 Small proline-rich protein 3 protein 20060315 {GO:0005515=IPI, GO:0005737=IEA, GO:0018149=IEA, GO:0008544=NAS, GO:0005198=TAS, GO:0030216=NAS, GO:0042060=TAS, GO:0031424=IEA} epidermis development, keratinization, keratinocyte differentiation, peptide cross-linking, wound healing cytoplasm protein binding, structural molecule activity Human UniProtKB:P08587 SPRR4 UniProtKB UniProtKB {GO:0018149=GO_REF:0000002, GO:0031424=GO_REF:0000037, GO:0005938=GO_REF:0000039} Q96PI1 Small proline-rich protein 4 protein 20130413 {GO:0018149=IEA, GO:0031424=IEA, GO:0005938=IEA} keratinization, peptide cross-linking cell cortex Human UniProtKB-SubCell:SL-0138 SPRY1 Reactome UniProtKB {GO:0001656=GO_REF:0000019, GO:0001657=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0005886=Reactome:REACT_12441, GO:0042059=Reactome:REACT_12484, GO:0001759=GO_REF:0000019, GO:0030027=GO_REF:0000029, GO:0051387=GO_REF:0000019, GO:0005829=Reactome:REACT_12500, GO:0046580=GO_REF:0000019, GO:0005737=GO_REF:0000029, GO:0007173=Reactome:REACT_9417, GO:0043407=GO_REF:0000019, GO:0040037=GO_REF:0000019, GO:0070373=GO_REF:0000019, GO:0034261=GO_REF:0000019} O43609 Protein sprouty homolog 1 protein 20130301 {GO:0001656=IEA, GO:0001657=IEA, GO:0008285=IEA, GO:0005886=TAS, GO:0042059=TAS, GO:0001759=IEA, GO:0030027=NAS, GO:0051387=IEA, GO:0005829=TAS, GO:0046580=IEA, GO:0005737=NAS, GO:0007173=TAS, GO:0043407=IEA, GO:0040037=IEA, GO:0070373=IEA, GO:0034261=IEA} epidermal growth factor receptor signaling pathway, metanephros development, negative regulation of ERK1 and ERK2 cascade, negative regulation of MAP kinase activity, negative regulation of Ras GTPase activity, negative regulation of Ras protein signal transduction, negative regulation of cell proliferation, negative regulation of epidermal growth factor receptor signaling pathway, negative regulation of fibroblast growth factor receptor signaling pathway, negative regulation of neurotrophin TRK receptor signaling pathway, organ induction, ureteric bud development cytoplasm, cytosol, lamellipodium, plasma membrane Human SPRY2 GOC UniProtKB {GO:0005515=PMID:21784977, GO:0051897=PMID:18070883, GO:0008285=GO_REF:0000019, GO:0071902=PMID:18070883, GO:0005886=Reactome:REACT_111241, GO:0060425=GO_REF:0000019, GO:0007605=GO_REF:0000019, GO:0005829=Reactome:REACT_111232, GO:0046580=GO_REF:0000019, GO:0033138=PMID:18070883, GO:0007173=Reactome:REACT_9417, GO:0043407=GO_REF:0000019, GO:0060437=GO_REF:0000019, GO:0070373=GO_REF:0000019, GO:0070374=PMID:18070883, GO:0034261=GO_REF:0000019, GO:0043066=PMID:18070883, GO:0042472=GO_REF:0000019, GO:0019901=PMID:20736167, GO:0005874=GO_REF:0000037, GO:0042059=Reactome:REACT_12484, GO:0032587=GO_REF:0000039, GO:0010801=PMID:20736167, GO:0030291=PMID:20736167, GO:0051387=GO_REF:0000019, GO:0010628=PMID:18070883, GO:0045165=GO_REF:0000019, GO:0008543=Reactome:REACT_9470, GO:0040037=GO_REF:0000019, GO:0048754=GO_REF:0000019, GO:0043539=PMID:18070883} O43597 Protein sprouty homolog 2 protein 20130413 {GO:0005515=IPI, GO:0051897=IMP, GO:0008285=IEA, GO:0071902=IMP, GO:0005886=TAS, GO:0060425=IEA, GO:0007605=IEA, GO:0005829=TAS, GO:0046580=IEA, GO:0033138=IMP, GO:0007173=TAS, GO:0043407=IEA, GO:0060437=IEA, GO:0070373=IEA, GO:0070374=IMP, GO:0034261=IEA, GO:0043066=IMP, GO:0042472=IEA, GO:0019901=IPI, GO:0005874=IEA, GO:0042059=TAS, GO:0032587=IEA, GO:0010801=IDA, GO:0030291=IC, GO:0051387=IEA, GO:0010628=IMP, GO:0045165=IEA, GO:0008543=TAS, GO:0040037=IEA, GO:0048754=IEA, GO:0043539=IMP} branching morphogenesis of an epithelial tube, cell fate commitment, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, inner ear morphogenesis, lung growth, lung morphogenesis, negative regulation of ERK1 and ERK2 cascade, negative regulation of MAP kinase activity, negative regulation of Ras GTPase activity, negative regulation of Ras protein signal transduction, negative regulation of apoptotic process, negative regulation of cell proliferation, negative regulation of epidermal growth factor receptor signaling pathway, negative regulation of fibroblast growth factor receptor signaling pathway, negative regulation of neurotrophin TRK receptor signaling pathway, negative regulation of peptidyl-threonine phosphorylation, positive regulation of ERK1 and ERK2 cascade, positive regulation of gene expression, positive regulation of peptidyl-serine phosphorylation, positive regulation of protein kinase B signaling cascade, positive regulation of protein serine/threonine kinase activity, sensory perception of sound cytosol, microtubule, plasma membrane, ruffle membrane protein binding, protein kinase binding, protein serine/threonine kinase activator activity, protein serine/threonine kinase inhibitor activity Human SPRY3 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000039, GO:0016020=GO_REF:0000029, GO:0007275=PMID:9458049, GO:0009966=GO_REF:0000002} O43610 Protein sprouty homolog 3 protein 20061026 {GO:0003674=ND, GO:0005737=IEA, GO:0016020=NAS, GO:0007275=NAS, GO:0009966=IEA} multicellular organismal development, regulation of signal transduction cytoplasm, membrane molecular_function Human SPRY4 IntAct UniProtKB {GO:0005515=PMID:12027893, GO:0005737=GO_REF:0000039, GO:0043407=GO_REF:0000019, GO:0032587=GO_REF:0000039, GO:0007275=GO_REF:0000037} Q9C004 Protein sprouty homolog 4 protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0043407=IEA, GO:0032587=IEA, GO:0007275=IEA} multicellular organismal development, negative regulation of MAP kinase activity cytoplasm, ruffle membrane protein binding Human UniProtKB:Q15569 SPRYD3 null null {} null null null null {} null null null SPRYD7 null null {} null null null null {} null null null SPSB1 UniPathway UniProtKB {GO:0035556=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0016567=GO_REF:0000041} Q96BD6 SPRY domain-containing SOCS box protein 1 protein 20130413 {GO:0035556=IEA, GO:0005737=IEA, GO:0016567=IEA} intracellular signal transduction, protein ubiquitination cytoplasm Human UniPathway:UPA00143 SPSB2 IntAct UniProtKB {GO:0005515=PMID:19159283, GO:0035556=GO_REF:0000002, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000039, GO:0016567=GO_REF:0000041, GO:0005575=GO_REF:0000015} Q99619 SPRY domain-containing SOCS box protein 2 protein 20130415 {GO:0005515=IPI, GO:0035556=IEA, GO:0008150=ND, GO:0003674=ND, GO:0005737=IEA, GO:0016567=IEA, GO:0005575=ND} biological_process, intracellular signal transduction, protein ubiquitination cellular_component, cytoplasm molecular_function, protein binding Human UniProtKB:Q15369 SPSB3 UniPathway UniProtKB {GO:0035556=GO_REF:0000002, GO:0016567=GO_REF:0000041} Q6PJ21 SPRY domain-containing SOCS box protein 3 protein 20130413 {GO:0035556=IEA, GO:0016567=IEA} intracellular signal transduction, protein ubiquitination Human UniPathway:UPA00143 SPSB4 IntAct UniProtKB {GO:0005515=PMID:19159283, GO:0035556=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0016567=GO_REF:0000041} Q96A44 SPRY domain-containing SOCS box protein 4 protein 20130415 {GO:0005515=IPI, GO:0035556=IEA, GO:0005737=IEA, GO:0016567=IEA} intracellular signal transduction, protein ubiquitination cytoplasm protein binding Human UniProtKB:Q15369 SPTA1 BHF-UCL UniProtKB {GO:0005515=PMID:12820899, GO:0007009=GO_REF:0000019, GO:0030097=GO_REF:0000019, GO:0008091=PMID:1634521, GO:0046982=GO_REF:0000019, GO:0008360=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0031235=PMID:10950304, GO:0032437=GO_REF:0000019, GO:0014731=PMID:379653, GO:0015629=PMID:10950304, GO:0051693=GO_REF:0000037, GO:0032092=GO_REF:0000019, GO:0005829=Reactome:REACT_22148, GO:0051015=PMID:1634521, GO:0007411=Reactome:REACT_18266, GO:0006779=GO_REF:0000019, GO:0042102=GO_REF:0000019, GO:0005200=PMID:1634521, GO:0007015=PMID:1634521, GO:0002260=GO_REF:0000019} P02549 Spectrin alpha chain, erythrocytic 1 protein 20090206 {GO:0005515=IPI, GO:0007009=IEA, GO:0030097=IEA, GO:0008091=TAS, GO:0046982=IEA, GO:0008360=IEA, GO:0005509=IEA, GO:0031235=TAS, GO:0032437=IEA, GO:0014731=IDA, GO:0015629=TAS, GO:0051693=IEA, GO:0032092=IEA, GO:0005829=TAS, GO:0051015=TAS, GO:0007411=TAS, GO:0006779=IEA, GO:0042102=IEA, GO:0005200=TAS, GO:0007015=TAS, GO:0002260=IEA} actin filament capping, actin filament organization, axon guidance, hemopoiesis, lymphocyte homeostasis, plasma membrane organization, porphyrin-containing compound biosynthetic process, positive regulation of T cell proliferation, positive regulation of protein binding, regulation of cell shape actin cytoskeleton, cuticular plate, cytosol, intrinsic to internal side of plasma membrane, spectrin, spectrin-associated cytoskeleton actin filament binding, calcium ion binding, protein binding, protein heterodimerization activity, structural constituent of cytoskeleton Human SPTAN1 HPA UniProtKB {GO:0005515=PMID:12820899, GO:0008091=PMID:2307671, GO:0005516=GO_REF:0000037, GO:0030018=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0006915=Reactome:REACT_578, GO:0030507=GO_REF:0000019, GO:0032437=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0016328=GO_REF:0000019, GO:0006921=Reactome:REACT_995, GO:0043231=GO_REF:0000052, GO:0051693=GO_REF:0000037, GO:0005829=Reactome:REACT_22148, GO:0005916=GO_REF:0000019, GO:0016020=PMID:2307671, GO:0007411=Reactome:REACT_18266, GO:0015630=GO_REF:0000052, GO:0005200=PMID:2307671} Q13813 Spectrin alpha chain, non-erythrocytic 1 protein 20101115 {GO:0005515=IPI, GO:0008091=TAS, GO:0005516=IEA, GO:0030018=IEA, GO:0046982=IEA, GO:0005509=IEA, GO:0006915=TAS, GO:0030507=IEA, GO:0032437=IEA, GO:0003779=IEA, GO:0016328=IEA, GO:0006921=TAS, GO:0043231=IDA, GO:0051693=IEA, GO:0005829=TAS, GO:0005916=IEA, GO:0016020=TAS, GO:0007411=TAS, GO:0015630=IDA, GO:0005200=TAS} actin filament capping, apoptotic process, axon guidance, cellular component disassembly involved in execution phase of apoptosis Z disc, cuticular plate, cytosol, fascia adherens, intracellular membrane-bounded organelle, lateral plasma membrane, membrane, microtubule cytoskeleton, spectrin actin binding, calcium ion binding, calmodulin binding, protein binding, protein heterodimerization activity, spectrin binding, structural constituent of cytoskeleton Human SPTB BHF-UCL UniProtKB {GO:0007009=GO_REF:0000019, GO:0030097=GO_REF:0000019, GO:0005515=PMID:16060676, GO:0008091=GO_REF:0000002, GO:0046982=GO_REF:0000019, GO:0030506=PMID:8159688, GO:0031235=PMID:10950304, GO:0003779=PMID:2195026, GO:0014731=PMID:379653, GO:0015629=PMID:10950304, GO:0051693=GO_REF:0000037, GO:0005829=Reactome:REACT_22148, GO:0043234=PMID:16060676, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0051015=PMID:16060676, GO:0007411=Reactome:REACT_18266, GO:0006779=GO_REF:0000019, GO:0005200=GO_REF:0000002} P11277 Spectrin beta chain, erythrocytic protein 20120606 {GO:0007009=IEA, GO:0030097=IEA, GO:0005515=IPI, GO:0008091=IEA, GO:0046982=IEA, GO:0030506=IPI, GO:0031235=TAS, GO:0003779=TAS, GO:0014731=IDA, GO:0015629=TAS, GO:0051693=IEA, GO:0005829=TAS, GO:0043234=IDA, GO:0005737=IDA, GO:0005543=IEA, GO:0051015=IDA, GO:0007411=TAS, GO:0006779=IEA, GO:0005200=IEA} actin filament capping, axon guidance, hemopoiesis, plasma membrane organization, porphyrin-containing compound biosynthetic process actin cytoskeleton, cytoplasm, cytosol, intrinsic to internal side of plasma membrane, protein complex, spectrin, spectrin-associated cytoskeleton actin binding, actin filament binding, ankyrin binding, phospholipid binding, protein binding, protein heterodimerization activity, structural constituent of cytoskeleton Human UniProtKB:P16157 SPTBN1 BHF-UCL UniProtKB {GO:0007009=PMID:17620337, GO:0005515=PMID:17043677, GO:0008091=GO_REF:0000002, GO:0005516=GO_REF:0000037, GO:0005886=GO_REF:0000019, GO:0043001=PMID:17620337, GO:0000281=PMID:17620337, GO:0072661=GO_REF:0000019, GO:0030506=PMID:17620337, GO:0005730=PMID:9537418, GO:0032437=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0005634=GO_REF:0000019, GO:0014731=PMID:17620337, GO:0031430=GO_REF:0000039, GO:0005829=Reactome:REACT_22148, GO:0051693=GO_REF:0000037, GO:0007182=GO_REF:0000019, GO:0005737=PMID:9537418, GO:0005543=GO_REF:0000002, GO:0007411=Reactome:REACT_18266, GO:0007184=GO_REF:0000019, GO:0005200=PMID:17620337, GO:0030673=GO_REF:0000024} Q01082 Spectrin beta chain, non-erythrocytic 1 protein 20120607 {GO:0007009=IMP, GO:0005515=IPI, GO:0008091=IEA, GO:0005516=IEA, GO:0005886=IEA, GO:0043001=IMP, GO:0000281=IMP, GO:0072661=IEA, GO:0030506=NAS, GO:0005730=IDA, GO:0032437=IEA, GO:0003779=IEA, GO:0005634=IEA, GO:0014731=NAS, GO:0031430=IEA, GO:0005829=TAS, GO:0051693=IEA, GO:0007182=IEA, GO:0005737=IDA, GO:0005543=IEA, GO:0007411=TAS, GO:0007184=IEA, GO:0005200=IMP, GO:0030673=ISS} Golgi to plasma membrane protein transport, SMAD protein import into nucleus, actin filament capping, axon guidance, common-partner SMAD protein phosphorylation, cytokinesis after mitosis, plasma membrane organization, protein targeting to plasma membrane M band, axolemma, cuticular plate, cytoplasm, cytosol, nucleolus, nucleus, plasma membrane, spectrin, spectrin-associated cytoskeleton actin binding, ankyrin binding, calmodulin binding, phospholipid binding, protein binding, structural constituent of cytoskeleton Human SPTBN2 Reactome UniProtKB {GO:0008219=GO_REF:0000037, GO:0008091=PMID:9826670, GO:0003779=GO_REF:0000037, GO:0007416=GO_REF:0000019, GO:0051693=GO_REF:0000037, GO:0005829=Reactome:REACT_120995, GO:0019886=Reactome:REACT_121399, GO:0005543=GO_REF:0000002, GO:0035264=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0043025=GO_REF:0000019, GO:0005200=PMID:9826670, GO:0021692=GO_REF:0000019, GO:0030534=GO_REF:0000019, GO:0016192=PMID:9826670} O15020 Spectrin beta chain, non-erythrocytic 2 protein 20130301 {GO:0008219=IEA, GO:0008091=IDA, GO:0003779=IEA, GO:0007416=IEA, GO:0051693=IEA, GO:0005829=TAS, GO:0019886=TAS, GO:0005543=IEA, GO:0035264=IEA, GO:0007411=TAS, GO:0043025=IEA, GO:0005200=TAS, GO:0021692=IEA, GO:0030534=IEA, GO:0016192=IDA} actin filament capping, adult behavior, antigen processing and presentation of exogenous peptide antigen via MHC class II, axon guidance, cell death, cerebellar Purkinje cell layer morphogenesis, multicellular organism growth, synapse assembly, vesicle-mediated transport cytosol, neuronal cell body, spectrin actin binding, phospholipid binding, structural constituent of cytoskeleton Human SPTBN4 BHF-UCL UniProtKB {GO:0005515=PMID:12812986, GO:0008091=PMID:11086001, GO:0005886=GO_REF:0000024, GO:0007605=GO_REF:0000024, GO:0007409=GO_REF:0000024, GO:0016363=PMID:11294830, GO:0005829=Reactome:REACT_22148, GO:0070852=GO_REF:0000024, GO:0043194=GO_REF:0000024, GO:0005737=PMID:11294830, GO:0005543=GO_REF:0000002, GO:0005912=GO_REF:0000024, GO:0007411=Reactome:REACT_18266, GO:0033135=GO_REF:0000024, GO:0007628=GO_REF:0000024, GO:0040018=GO_REF:0000019, GO:0016192=PMID:11294830, GO:0061337=GO_REF:0000024, GO:0007016=PMID:11086001, GO:0010459=GO_REF:0000024, GO:0019902=PMID:11086001, GO:0030506=PMID:11294830, GO:0030507=GO_REF:0000024, GO:0003779=GO_REF:0000024, GO:0021952=GO_REF:0000024, GO:0051693=GO_REF:0000037, GO:0009566=GO_REF:0000019, GO:0033268=GO_REF:0000024, GO:0016020=PMID:11086001, GO:0016605=PMID:11294830, GO:0005200=PMID:11294830} Q9H254 Spectrin beta chain, non-erythrocytic 4 protein 20120607 {GO:0005515=IPI, GO:0008091=IDA, GO:0005886=ISS, GO:0007605=ISS, GO:0007409=ISS, GO:0016363=IDA, GO:0005829=TAS, GO:0070852=ISS, GO:0043194=ISS, GO:0005737=IDA, GO:0005543=IEA, GO:0005912=ISS, GO:0007411=TAS, GO:0033135=ISS, GO:0007628=ISS, GO:0040018=IEA, GO:0016192=TAS, GO:0061337=ISS, GO:0007016=TAS, GO:0010459=ISS, GO:0019902=IPI, GO:0030506=IDA, GO:0030507=ISS, GO:0003779=ISS, GO:0021952=ISS, GO:0051693=IEA, GO:0009566=IEA, GO:0033268=ISS, GO:0016020=IDA, GO:0016605=IDA, GO:0005200=TAS} actin filament capping, adult walking behavior, axon guidance, axonogenesis, cardiac conduction, central nervous system projection neuron axonogenesis, cytoskeletal anchoring at plasma membrane, fertilization, negative regulation of heart rate, positive regulation of multicellular organism growth, regulation of peptidyl-serine phosphorylation, sensory perception of sound, vesicle-mediated transport PML body, adherens junction, axon initial segment, cell body fiber, cytoplasm, cytosol, membrane, node of Ranvier, nuclear matrix, plasma membrane, spectrin actin binding, ankyrin binding, phosphatase binding, phospholipid binding, protein binding, spectrin binding, structural constituent of cytoskeleton Human UniProtKB:Q5BJU8 SPTBN5 Reactome UniProtKB {GO:0008091=PMID:10764729, GO:0030036=PMID:10764729, GO:0005543=GO_REF:0000002, GO:0016020=PMID:10764729, GO:0007411=Reactome:REACT_18266, GO:0003779=PMID:10764729, GO:0005829=Reactome:REACT_22148, GO:0051693=GO_REF:0000037} Q9NRC6 Spectrin beta chain, non-erythrocytic 5 protein 20130301 {GO:0008091=NAS, GO:0030036=NAS, GO:0005543=IEA, GO:0016020=NAS, GO:0007411=TAS, GO:0003779=NAS, GO:0005829=TAS, GO:0051693=IEA} actin cytoskeleton organization, actin filament capping, axon guidance cytosol, membrane, spectrin actin binding, phospholipid binding Human SPTLC1 Reactome UniProtKB {GO:0005515=PMID:20182505, GO:0006665=Reactome:REACT_19323, GO:0004758=PMID:19416851, GO:0006686=GO_REF:0000019, GO:0030148=Reactome:REACT_115810, GO:0035339=PMID:20182505, GO:0044281=Reactome:REACT_111217, GO:0030170=GO_REF:0000002, GO:0005789=Reactome:REACT_19401, GO:0016021=GO_REF:0000037, GO:0017059=PMID:19416851, GO:0046512=GO_REF:0000019, GO:0046511=GO_REF:0000019} O15269 Serine palmitoyltransferase 1 protein 20130213 {GO:0005515=IPI, GO:0006665=TAS, GO:0004758=IDA, GO:0006686=IEA, GO:0030148=TAS, GO:0035339=IDA, GO:0044281=TAS, GO:0030170=IEA, GO:0005789=TAS, GO:0016021=IEA, GO:0017059=IDA, GO:0046512=IEA, GO:0046511=IEA} small molecule metabolic process, sphinganine biosynthetic process, sphingolipid biosynthetic process, sphingolipid metabolic process, sphingomyelin biosynthetic process, sphingosine biosynthetic process SPOTS complex, endoplasmic reticulum membrane, integral to membrane, serine C-palmitoyltransferase complex protein binding, pyridoxal phosphate binding, serine C-palmitoyltransferase activity Human SPTLC2 Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0004758=PMID:20920666, GO:0009058=GO_REF:0000002, GO:0006686=GO_REF:0000019, GO:0030148=Reactome:REACT_115810, GO:0044281=Reactome:REACT_111217, GO:0005739=GO_REF:0000019, GO:0030170=GO_REF:0000002, GO:0005789=Reactome:REACT_19401, GO:0016021=GO_REF:0000037, GO:0017059=PMID:19416851, GO:0046512=GO_REF:0000019, GO:0016740=GO_REF:0000002, GO:0046511=GO_REF:0000019} O15270 Serine palmitoyltransferase 2 protein 20130213 {GO:0006665=TAS, GO:0004758=IDA, GO:0009058=IEA, GO:0006686=IEA, GO:0030148=TAS, GO:0044281=TAS, GO:0005739=IEA, GO:0030170=IEA, GO:0005789=TAS, GO:0016021=IEA, GO:0017059=IDA, GO:0046512=IEA, GO:0016740=IEA, GO:0046511=IEA} biosynthetic process, small molecule metabolic process, sphinganine biosynthetic process, sphingolipid biosynthetic process, sphingolipid metabolic process, sphingomyelin biosynthetic process, sphingosine biosynthetic process endoplasmic reticulum membrane, integral to membrane, mitochondrion, serine C-palmitoyltransferase complex pyridoxal phosphate binding, serine C-palmitoyltransferase activity, transferase activity Human SPTSSA UniProtKB UniProtKB {GO:0005515=PMID:19416851, GO:0004758=PMID:19416851, GO:0030148=PMID:19416851, GO:0016021=GO_REF:0000037, GO:0017059=PMID:19416851} Q969W0 Serine palmitoyltransferase small subunit A protein 20090519 {GO:0005515=IPI, GO:0004758=IDA, GO:0030148=TAS, GO:0016021=IEA, GO:0017059=IDA} sphingolipid biosynthetic process integral to membrane, serine C-palmitoyltransferase complex protein binding, serine C-palmitoyltransferase activity Human SPTY2D1 BHF-UCL UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q68D10 Protein SPT2 homolog protein 20110713 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human SPZ1 HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9BXG8 Spermatogenic leucine zipper protein 1 protein 20110516 {GO:0006355=IEA, GO:0005737=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus DNA binding Human SQLE Reactome UniProtKB {GO:0006695=Reactome:REACT_9405, GO:0006725=GO_REF:0000019, GO:0010033=GO_REF:0000019, GO:0050660=GO_REF:0000002, GO:0005789=Reactome:REACT_147725, GO:0016126=PMID:9286711, GO:0004506=Reactome:REACT_9420, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0043231=GO_REF:0000029, GO:0008203=GO_REF:0000019} Q14534 Squalene monooxygenase protein 20130213 {GO:0006695=TAS, GO:0006725=IEA, GO:0010033=IEA, GO:0050660=IEA, GO:0005789=TAS, GO:0016126=NAS, GO:0004506=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0043231=NAS, GO:0008203=IEA} cellular aromatic compound metabolic process, cholesterol biosynthetic process, cholesterol metabolic process, response to organic substance, small molecule metabolic process, sterol biosynthetic process endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle flavin adenine dinucleotide binding, squalene monooxygenase activity Human SQRDL HPA UniProtKB {GO:0034641=Reactome:REACT_13, GO:0005737=GO_REF:0000052, GO:0070224=Reactome:REACT_115885, GO:0000096=Reactome:REACT_115639, GO:0000098=Reactome:REACT_115654, GO:0005743=Reactome:REACT_115885, GO:0016491=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0070221=Reactome:REACT_116010} Q9Y6N5 Sulfide:quinone oxidoreductase, mitochondrial protein 20090616 {GO:0034641=TAS, GO:0005737=IDA, GO:0070224=TAS, GO:0000096=TAS, GO:0000098=TAS, GO:0005743=TAS, GO:0016491=IEA, GO:0044281=TAS, GO:0070221=TAS} cellular nitrogen compound metabolic process, small molecule metabolic process, sulfide oxidation, using sulfide:quinone oxidoreductase, sulfur amino acid catabolic process, sulfur amino acid metabolic process cytoplasm, mitochondrial inner membrane oxidoreductase activity, sulfide:quinone oxidoreductase activity Human SQSTM1 BHF-UCL UniProtKB {GO:0005515=PMID:22190034, GO:0006511=PMID:8702753, GO:0043130=PMID:12857745, GO:0005783=GO_REF:0000039, GO:0046578=PMID:8618896, GO:0005764=GO_REF:0000039, GO:0051291=GO_REF:0000019, GO:0030154=GO_REF:0000037, GO:0042803=GO_REF:0000019, GO:0042802=PMID:20562859, GO:0005829=Reactome:REACT_22171, GO:0035556=PMID:8650207, GO:0008104=PMID:8650207, GO:0000932=PMID:20357094, GO:0045944=PMID:12857745, GO:0005080=PMID:14676191, GO:0016197=PMID:12857745, GO:0042169=PMID:8650207, GO:0043122=PMID:12857745, GO:0070530=GO_REF:0000019, GO:0030971=PMID:8650207, GO:0048011=Reactome:REACT_13776, GO:0043066=Reactome:REACT_13537, GO:0005776=PMID:17580304, GO:0019901=PMID:8650207, GO:0005770=GO_REF:0000039, GO:0016236=GO_REF:0000024, GO:0006914=PMID:19816510, GO:0006950=PMID:12857745, GO:0006915=Reactome:REACT_13643, GO:0031410=GO_REF:0000037, GO:0000407=GO_REF:0000019, GO:0097190=Reactome:REACT_13720, GO:0004674=PMID:8618896, GO:0001934=GO_REF:0000019, GO:0005654=Reactome:REACT_13601, GO:0008270=GO_REF:0000002} Q13501 Sequestosome-1 protein 20100107 {GO:0005515=IPI, GO:0006511=TAS, GO:0043130=IDA, GO:0005783=IEA, GO:0046578=NAS, GO:0005764=IEA, GO:0051291=IEA, GO:0030154=IEA, GO:0042803=IEA, GO:0042802=IPI, GO:0005829=TAS, GO:0035556=TAS, GO:0008104=TAS, GO:0000932=IDA, GO:0045944=TAS, GO:0005080=IPI, GO:0016197=TAS, GO:0042169=IDA, GO:0043122=IMP, GO:0070530=IEA, GO:0030971=TAS, GO:0048011=TAS, GO:0043066=TAS, GO:0005776=IDA, GO:0019901=IDA, GO:0005770=IEA, GO:0016236=ISS, GO:0006914=TAS, GO:0006950=TAS, GO:0006915=TAS, GO:0031410=IEA, GO:0000407=IEA, GO:0097190=TAS, GO:0004674=NAS, GO:0001934=IEA, GO:0005654=TAS, GO:0008270=IEA} apoptotic process, apoptotic signaling pathway, autophagy, cell differentiation, endosomal transport, intracellular signal transduction, macroautophagy, negative regulation of apoptotic process, neurotrophin TRK receptor signaling pathway, positive regulation of protein phosphorylation, positive regulation of transcription from RNA polymerase II promoter, protein heterooligomerization, protein localization, regulation of I-kappaB kinase/NF-kappaB cascade, regulation of Ras protein signal transduction, response to stress, ubiquitin-dependent protein catabolic process autophagic vacuole, cytoplasmic mRNA processing body, cytoplasmic vesicle, cytosol, endoplasmic reticulum, late endosome, lysosome, nucleoplasm, pre-autophagosomal structure K63-linked polyubiquitin binding, SH2 domain binding, identical protein binding, protein binding, protein homodimerization activity, protein kinase C binding, protein kinase binding, protein serine/threonine kinase activity, receptor tyrosine kinase binding, ubiquitin binding, zinc ion binding Human SRA1 UniProtKB UniProtKB {GO:0005667=GO_REF:0000019, GO:0008283=PMID:14517287, GO:0003713=PMID:10199399, GO:0010861=GO_REF:0000019, GO:0006915=PMID:14517287, GO:0005634=PMID:12565891, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0030154=PMID:14517287, GO:0005737=GO_REF:0000039, GO:0030374=GO_REF:0000019, GO:0030529=PMID:10199399, GO:0045944=GO_REF:0000019, GO:0031252=GO_REF:0000019} Q9HD15 Steroid receptor RNA activator 1 protein 20060404 {GO:0005667=IEA, GO:0008283=IDA, GO:0003713=IDA, GO:0010861=IEA, GO:0006915=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA, GO:0030154=IDA, GO:0005737=IEA, GO:0030374=IEA, GO:0030529=IPI, GO:0045944=IEA, GO:0031252=IEA} apoptotic process, cell differentiation, cell proliferation, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cell leading edge, cytoplasm, nucleus, ribonucleoprotein complex, transcription factor complex DNA binding, ligand-dependent nuclear receptor transcription coactivator activity, thyroid hormone receptor activator activity, transcription coactivator activity Human UniProtKB:Q15788 SRBD1 UniProtKB UniProtKB {GO:0006139=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0016788=GO_REF:0000002} Q8N5C6 S1 RNA-binding domain-containing protein 1 protein 20130413 {GO:0006139=IEA, GO:0003723=IEA, GO:0016788=IEA} nucleobase-containing compound metabolic process RNA binding, hydrolase activity, acting on ester bonds Human UniProtKB-KW:KW-0694 SRC BHF-UCL UniProtKB {GO:0005515=PMID:22439932, GO:0045453=GO_REF:0000024, GO:0090263=GO_REF:0000019, GO:0050900=Reactome:REACT_12051, GO:0005764=PMID:20605918, GO:0007243=PMID:15248232, GO:0042802=PMID:17254967, GO:0046777=PMID:16441665, GO:0007172=PMID:9924018, GO:0007173=Reactome:REACT_9417, GO:0007411=Reactome:REACT_18266, GO:0016301=Reactome:REACT_9997, GO:0071393=GO_REF:0000024, GO:0070374=GO_REF:0000019, GO:0005856=GO_REF:0000039, GO:0042169=PMID:8070403, GO:0050847=GO_REF:0000024, GO:0030168=Reactome:REACT_798, GO:0018108=PMID:22732588, GO:2001243=PMID:19767770, GO:0044325=PMID:12538589, GO:0007049=GO_REF:0000037, GO:0005178=PMID:19267251, GO:0046875=PMID:12925710, GO:0008543=Reactome:REACT_9470, GO:0005070=PMID:9020193, GO:0045087=Reactome:REACT_6802, GO:0033146=GO_REF:0000019, GO:0038096=Reactome:REACT_160123, GO:0060444=GO_REF:0000019, GO:0016044=Reactome:REACT_11123, GO:0020037=PMID:21036157, GO:2001237=PMID:19767770, GO:0071803=GO_REF:0000019, GO:0060065=GO_REF:0000019, GO:0048477=GO_REF:0000019, GO:0005886=Reactome:REACT_115797, GO:0031295=Reactome:REACT_19344, GO:0005743=PMID:12615910, GO:0045124=PMID:19267251, GO:0005634=GO_REF:0000039, GO:0007265=Reactome:REACT_12033, GO:0033625=PMID:19267251, GO:0051895=GO_REF:0000024, GO:0005829=Reactome:REACT_160304, GO:0005737=PMID:16441665, GO:0007155=GO_REF:0000037, GO:0070555=PMID:19281832, GO:0048011=Reactome:REACT_11061, GO:0005770=PMID:20605918, GO:0005102=PMID:19332538, GO:0005524=GO_REF:0000037, GO:0007165=PMID:9020193, GO:0004672=Reactome:REACT_23900, GO:0007596=Reactome:REACT_604, GO:0005901=PMID:17848177, GO:0019048=GO_REF:0000037, GO:0043114=PMID:19267251, GO:0030900=GO_REF:0000019, GO:0004713=Reactome:REACT_111112, GO:0004715=PMID:19267251} P12931 Proto-oncogene tyrosine-protein kinase Src protein 20120531 {GO:0005515=IPI, GO:0045453=ISS, GO:0090263=IEA, GO:0050900=TAS, GO:0005764=IDA, GO:0007243=IDA, GO:0042802=IPI, GO:0046777=IDA, GO:0007172=TAS, GO:0007173=TAS, GO:0007411=TAS, GO:0016301=TAS, GO:0071393=ISS, GO:0070374=IEA, GO:0005856=IEA, GO:0042169=IPI, GO:0050847=ISS, GO:0030168=TAS, GO:0018108=IDA, GO:2001243=IMP, GO:0044325=IPI, GO:0007049=IEA, GO:0005178=TAS, GO:0046875=IPI, GO:0008543=TAS, GO:0005070=TAS, GO:0045087=TAS, GO:0033146=IEA, GO:0038096=TAS, GO:0060444=IEA, GO:0016044=TAS, GO:0020037=IDA, GO:2001237=IMP, GO:0071803=IEA, GO:0060065=IEA, GO:0048477=IEA, GO:0005886=TAS, GO:0031295=TAS, GO:0005743=IDA, GO:0045124=TAS, GO:0005634=IEA, GO:0007265=TAS, GO:0033625=TAS, GO:0051895=ISS, GO:0005829=TAS, GO:0005737=IDA, GO:0007155=IEA, GO:0070555=IMP, GO:0048011=TAS, GO:0005770=IDA, GO:0005102=IPI, GO:0005524=IEA, GO:0007165=TAS, GO:0004672=TAS, GO:0007596=TAS, GO:0005901=IDA, GO:0019048=IEA, GO:0043114=TAS, GO:0030900=IEA, GO:0004713=TAS, GO:0004715=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, Ras protein signal transduction, T cell costimulation, axon guidance, blood coagulation, bone resorption, branching involved in mammary gland duct morphogenesis, cell adhesion, cell cycle, cellular membrane organization, cellular response to progesterone stimulus, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, forebrain development, innate immune response, intracellular protein kinase cascade, leukocyte migration, negative regulation of extrinsic apoptotic signaling pathway, negative regulation of focal adhesion assembly, negative regulation of intrinsic apoptotic signaling pathway, neurotrophin TRK receptor signaling pathway, oogenesis, peptidyl-tyrosine phosphorylation, platelet activation, positive regulation of ERK1 and ERK2 cascade, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of integrin activation, positive regulation of podosome assembly, progesterone receptor signaling pathway, protein autophosphorylation, regulation of bone resorption, regulation of intracellular estrogen receptor signaling pathway, regulation of vascular permeability, response to interleukin-1, signal complex assembly, signal transduction, uterus development, virus-host interaction caveola, cytoplasm, cytoskeleton, cytosol, late endosome, lysosome, mitochondrial inner membrane, nucleus, plasma membrane ATP binding, SH2 domain binding, SH3/SH2 adaptor activity, ephrin receptor binding, heme binding, identical protein binding, integrin binding, ion channel binding, kinase activity, non-membrane spanning protein tyrosine kinase activity, protein binding, protein kinase activity, protein tyrosine kinase activity, receptor binding Human UniProtKB:Q9WUD9 SRCAP GOC UniProtKB {GO:0043234=PMID:14966270, GO:0005794=GO_REF:0000052, GO:0016573=PMID:10347196, GO:0006357=PMID:10347196, GO:0019048=GO_REF:0000037, GO:0003713=PMID:10347196, GO:0004386=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0004402=PMID:10347196, GO:0006351=GO_REF:0000037} Q6ZRS2 Helicase SRCAP protein 20130413 {GO:0043234=IDA, GO:0005794=IDA, GO:0016573=TAS, GO:0006357=TAS, GO:0019048=IEA, GO:0003713=TAS, GO:0004386=IEA, GO:0005634=IDA, GO:0005524=IEA, GO:0003677=IEA, GO:0004402=TAS, GO:0006351=IEA} histone acetylation, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent, virus-host interaction Golgi apparatus, nucleus, protein complex ATP binding, DNA binding, helicase activity, histone acetyltransferase activity, transcription coactivator activity Human SRCIN1 IntAct UniProtKB {GO:0005515=PMID:17525734, GO:0030334=PMID:17525734, GO:0030424=GO_REF:0000024, GO:0005886=GO_REF:0000037, GO:0019901=PMID:17525734, GO:0061098=PMID:17525734, GO:0061099=PMID:17525734, GO:0019904=GO_REF:0000019, GO:0045202=GO_REF:0000024, GO:0014069=GO_REF:0000024, GO:0030175=GO_REF:0000019, GO:0015629=PMID:14657239, GO:0006887=GO_REF:0000037, GO:0030425=GO_REF:0000024, GO:0030027=GO_REF:0000019, GO:0005737=PMID:19146815, GO:0007162=GO_REF:0000019, GO:0045211=GO_REF:0000037, GO:0043025=GO_REF:0000019, GO:0050709=GO_REF:0000019, GO:0034446=PMID:17525734, GO:0061001=PMID:19146815, GO:0005925=PMID:14657239} Q9C0H9 SRC kinase signaling inhibitor 1 protein 20130415 {GO:0005515=IPI, GO:0030334=IMP, GO:0030424=ISS, GO:0005886=IEA, GO:0019901=IDA, GO:0061098=IDA, GO:0061099=IDA, GO:0019904=IEA, GO:0045202=ISS, GO:0014069=ISS, GO:0030175=IEA, GO:0015629=IDA, GO:0006887=IEA, GO:0030425=ISS, GO:0030027=IEA, GO:0005737=IDA, GO:0007162=IEA, GO:0045211=IEA, GO:0043025=IEA, GO:0050709=IEA, GO:0034446=IMP, GO:0061001=IMP, GO:0005925=IDA} exocytosis, negative regulation of cell adhesion, negative regulation of protein secretion, negative regulation of protein tyrosine kinase activity, positive regulation of protein tyrosine kinase activity, regulation of cell migration, regulation of dendritic spine morphogenesis, substrate adhesion-dependent cell spreading actin cytoskeleton, axon, cytoplasm, dendrite, filopodium, focal adhesion, lamellipodium, neuronal cell body, plasma membrane, postsynaptic density, postsynaptic membrane, synapse protein binding, protein domain specific binding, protein kinase binding Human UniProtKB:P12931 SRD5A1 Reactome UniProtKB {GO:0006629=GO_REF:0000002, GO:0003865=PMID:17986282, GO:0006702=Reactome:REACT_11059, GO:0009055=PMID:1686016, GO:0044281=Reactome:REACT_111217, GO:0016627=GO_REF:0000002, GO:0030154=GO_REF:0000037, GO:0047751=GO_REF:0000003, GO:0007530=PMID:1686016, GO:0005737=GO_REF:0000002, GO:0005789=Reactome:REACT_22210, GO:0007548=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0008202=Reactome:REACT_11057} P18405 3-oxo-5-alpha-steroid 4-dehydrogenase 1 protein 20130301 {GO:0006629=IEA, GO:0003865=IDA, GO:0006702=TAS, GO:0009055=TAS, GO:0044281=TAS, GO:0016627=IEA, GO:0030154=IEA, GO:0047751=IEA, GO:0007530=NAS, GO:0005737=IEA, GO:0005789=TAS, GO:0007548=IEA, GO:0016021=IEA, GO:0008202=TAS} androgen biosynthetic process, cell differentiation, lipid metabolic process, sex determination, sex differentiation, small molecule metabolic process, steroid metabolic process cytoplasm, endoplasmic reticulum membrane, integral to membrane 3-oxo-5-alpha-steroid 4-dehydrogenase activity, cholestenone 5-alpha-reductase activity, electron carrier activity, oxidoreductase activity, acting on the CH-CH group of donors Human SRD5A3 Reactome UniProtKB {GO:0006629=GO_REF:0000002, GO:0003865=PMID:17986282, GO:0006702=Reactome:REACT_11059, GO:0019348=PMID:20637498, GO:0005783=PMID:20637498, GO:0016095=PMID:20637498, GO:0044281=Reactome:REACT_111217, GO:0016628=PMID:20637498, GO:0016627=GO_REF:0000002, GO:0047751=GO_REF:0000003, GO:0005737=GO_REF:0000002, GO:0005789=Reactome:REACT_22210, GO:0006486=GO_REF:0000041, GO:0016021=GO_REF:0000037, GO:0006488=PMID:20637498, GO:0008202=Reactome:REACT_11057} Q9H8P0 Polyprenol reductase protein 20130301 {GO:0006629=IEA, GO:0003865=IDA, GO:0006702=TAS, GO:0019348=IDA, GO:0005783=IDA, GO:0016095=IDA, GO:0044281=TAS, GO:0016628=IDA, GO:0016627=IEA, GO:0047751=IEA, GO:0005737=IEA, GO:0005789=TAS, GO:0006486=IEA, GO:0016021=IEA, GO:0006488=IMP, GO:0008202=TAS} androgen biosynthetic process, dolichol metabolic process, dolichol-linked oligosaccharide biosynthetic process, lipid metabolic process, polyprenol catabolic process, protein glycosylation, small molecule metabolic process, steroid metabolic process cytoplasm, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane 3-oxo-5-alpha-steroid 4-dehydrogenase activity, cholestenone 5-alpha-reductase activity, oxidoreductase activity, acting on the CH-CH group of donors, oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor Human SREBF1 BHF-UCL UniProtKB {GO:0006629=PMID:8156598, GO:0005515=PMID:14701856, GO:0008286=GO_REF:0000019, GO:0003700=PMID:16407292, GO:0032810=PMID:16407292, GO:0030324=GO_REF:0000019, GO:0005634=PMID:15358760, GO:0044281=Reactome:REACT_111217, GO:0005635=PMID:8156598, GO:0051591=GO_REF:0000019, GO:0032094=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0005829=Reactome:REACT_147887, GO:0032933=GO_REF:0000019, GO:0033762=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0032526=GO_REF:0000019, GO:0046676=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0003062=GO_REF:0000019, GO:0009267=PMID:16407292, GO:0008203=GO_REF:0000019, GO:0012507=GO_REF:0000039, GO:0008610=GO_REF:0000024, GO:0010867=GO_REF:0000024, GO:0006357=PMID:8156598, GO:0019901=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0019217=GO_REF:0000019, GO:0003677=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0009749=GO_REF:0000019, GO:0043565=GO_REF:0000019, GO:0044444=GO_REF:0000024, GO:0043234=GO_REF:0000019, GO:0070542=GO_REF:0000019, GO:0000139=Reactome:REACT_147876, GO:0016020=GO_REF:0000019, GO:0031065=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0005789=Reactome:REACT_147840, GO:0032570=GO_REF:0000019, GO:0005654=Reactome:REACT_147902, GO:0016021=GO_REF:0000037, GO:0045542=GO_REF:0000019} P36956 Sterol regulatory element-binding protein 1 protein 20111213 {GO:0006629=TAS, GO:0005515=IPI, GO:0008286=IEA, GO:0003700=IDA, GO:0032810=IDA, GO:0030324=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0005635=TAS, GO:0051591=IEA, GO:0032094=IEA, GO:0032403=IEA, GO:0005829=TAS, GO:0032933=IEA, GO:0033762=IEA, GO:0046983=IEA, GO:0032526=IEA, GO:0046676=IEA, GO:0044255=TAS, GO:0003062=IEA, GO:0009267=ISS, GO:0008203=IEA, GO:0012507=IEA, GO:0008610=ISS, GO:0010867=ISS, GO:0006357=TAS, GO:0019901=IEA, GO:0042493=IEA, GO:0007568=IEA, GO:0000122=IEA, GO:0019217=IEA, GO:0003677=ISS, GO:0006351=IEA, GO:0009749=IEA, GO:0043565=IEA, GO:0044444=ISS, GO:0043234=IEA, GO:0070542=IEA, GO:0000139=TAS, GO:0016020=IEA, GO:0031065=IEA, GO:0003682=IEA, GO:0005789=TAS, GO:0032570=IEA, GO:0005654=TAS, GO:0016021=IEA, GO:0045542=IEA} SREBP signaling pathway, aging, cellular lipid metabolic process, cellular response to starvation, cholesterol metabolic process, insulin receptor signaling pathway, lipid biosynthetic process, lipid metabolic process, lung development, negative regulation of insulin secretion, negative regulation of transcription from RNA polymerase II promoter, positive regulation of cholesterol biosynthetic process, positive regulation of histone deacetylation, positive regulation of triglyceride biosynthetic process, regulation of fatty acid metabolic process, regulation of heart rate by chemical signal, regulation of transcription from RNA polymerase II promoter, response to cAMP, response to drug, response to fatty acid, response to food, response to glucagon stimulus, response to glucose stimulus, response to progesterone stimulus, response to retinoic acid, small molecule metabolic process, transcription, DNA-dependent ER to Golgi transport vesicle membrane, Golgi membrane, cytoplasmic part, cytosol, endoplasmic reticulum membrane, integral to membrane, membrane, nuclear envelope, nucleoplasm, nucleus, protein complex DNA binding, chromatin binding, protein binding, protein complex binding, protein dimerization activity, protein kinase binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, sterol response element binding Human SREBF2 BHF-UCL UniProtKB {GO:0005515=PMID:20936779, GO:0006629=PMID:7903453, GO:2000188=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0005783=PMID:12202038, GO:0005634=PMID:19098903, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_147887, GO:0005737=PMID:19098903, GO:0032933=GO_REF:0000019, GO:0045944=PMID:12446768, GO:0032937=PMID:12242332, GO:0046983=GO_REF:0000002, GO:0044255=Reactome:REACT_22279, GO:0072368=PMID:15358760, GO:0008203=GO_REF:0000037, GO:0071499=PMID:15358760, GO:0012507=GO_REF:0000039, GO:0000247=PMID:12941800, GO:0070888=PMID:15358760, GO:0000978=PMID:15358760, GO:0008022=PMID:9242699, GO:0010886=PMID:15358760, GO:0006351=GO_REF:0000037, GO:0055098=PMID:15358760, GO:0000139=Reactome:REACT_147893, GO:0005789=Reactome:REACT_147893, GO:0090370=PMID:15358760, GO:0005654=Reactome:REACT_147902} Q12772 Sterol regulatory element-binding protein 2 protein 20120822 {GO:0005515=IPI, GO:0006629=TAS, GO:2000188=IEA, GO:0003700=IEA, GO:0005783=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0032933=IEA, GO:0045944=IDA, GO:0032937=IDA, GO:0046983=IEA, GO:0044255=TAS, GO:0072368=IDA, GO:0008203=IEA, GO:0071499=NAS, GO:0012507=IEA, GO:0000247=IDA, GO:0070888=IDA, GO:0000978=IDA, GO:0008022=IPI, GO:0010886=IDA, GO:0006351=IEA, GO:0055098=IEP, GO:0000139=TAS, GO:0005789=TAS, GO:0090370=IDA, GO:0005654=TAS} SREBP signaling pathway, cellular lipid metabolic process, cellular response to laminar fluid shear stress, cholesterol metabolic process, lipid metabolic process, negative regulation of cholesterol efflux, positive regulation of cholesterol storage, positive regulation of transcription from RNA polymerase II promoter, regulation of cholesterol homeostasis, regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter, response to low-density lipoprotein particle stimulus, small molecule metabolic process, transcription, DNA-dependent ER to Golgi transport vesicle membrane, Golgi membrane, SREBP-SCAP-Insig complex, cytoplasm, cytosol, endoplasmic reticulum, endoplasmic reticulum membrane, nucleoplasm, nucleus C-8 sterol isomerase activity, E-box binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, protein C-terminus binding, protein binding, protein dimerization activity, sequence-specific DNA binding transcription factor activity Human SREK1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005681=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0043231=GO_REF:0000052} Q8WXA9 Splicing regulatory glutamine/lysine-rich protein 1 protein 20111111 {GO:0005739=IDA, GO:0008380=IEA, GO:0006397=IEA, GO:0000166=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005681=IEA, GO:0003676=IEA, GO:0043231=IDA} RNA splicing, mRNA processing intracellular membrane-bounded organelle, mitochondrion, nucleolus, nucleus, spliceosomal complex nucleic acid binding, nucleotide binding Human SRF BHF-UCL UniProtKB {GO:0005515=PMID:8887666, GO:0000790=GO_REF:0000019, GO:0003700=PMID:3203386, GO:0006366=PMID:3203386, GO:0003705=GO_REF:0000019, GO:0045597=PMID:17576768, GO:0010736=PMID:3203386, GO:0010735=PMID:8887666, GO:0051491=GO_REF:0000019, GO:0060292=GO_REF:0000019, GO:0030155=GO_REF:0000019, GO:0042803=PMID:3203386, GO:0031175=GO_REF:0000019, GO:1900222=PMID:19098903, GO:0001947=GO_REF:0000024, GO:0022028=GO_REF:0000019, GO:0007507=GO_REF:0000024, GO:0048589=GO_REF:0000019, GO:0070830=GO_REF:0000019, GO:0010669=GO_REF:0000019, GO:0055003=GO_REF:0000019, GO:0042789=GO_REF:0000024, GO:0008306=GO_REF:0000019, GO:0001707=GO_REF:0000019, GO:0051150=PMID:17215356, GO:0045214=GO_REF:0000019, GO:0009636=PMID:12660819, GO:0030168=GO_REF:0000019, GO:0000978=GO_REF:0000024, GO:0001701=GO_REF:0000019, GO:0031490=GO_REF:0000019, GO:0060347=GO_REF:0000019, GO:0035855=GO_REF:0000019, GO:0033561=GO_REF:0000019, GO:0043589=GO_REF:0000019, GO:0090398=PMID:15282327, GO:0008134=PMID:16054032, GO:0030038=GO_REF:0000019, GO:0035912=GO_REF:0000019, GO:0043149=GO_REF:0000019, GO:0002042=PMID:15180964, GO:0005634=PMID:2108863, GO:0060261=PMID:8887666, GO:0046716=GO_REF:0000024, GO:0005737=PMID:15180964, GO:0045987=PMID:17215356, GO:0048666=PMID:17200232, GO:0061029=GO_REF:0000019, GO:0045944=PMID:17576768, GO:0048821=GO_REF:0000019, GO:0009725=PMID:17975004, GO:0034097=PMID:3203386, GO:0030220=GO_REF:0000019, GO:0090136=GO_REF:0000019, GO:0001666=PMID:19098903, GO:0001569=GO_REF:0000019, GO:0002011=GO_REF:0000019, GO:0090009=GO_REF:0000019, GO:0060055=PMID:15180964, GO:0001228=GO_REF:0000024, GO:0001829=PMID:17576768, GO:0060218=GO_REF:0000019, GO:0045059=GO_REF:0000019, GO:0021766=GO_REF:0000019, GO:0001077=PMID:20808827, GO:0001076=GO_REF:0000019, GO:0007160=GO_REF:0000019, GO:0060947=GO_REF:0000019, GO:0001764=GO_REF:0000019, GO:0003257=PMID:19783823} P11831 Serum response factor protein 20120822 {GO:0005515=IPI, GO:0000790=IEA, GO:0003700=IDA, GO:0006366=IDA, GO:0003705=IEA, GO:0045597=IDA, GO:0010736=IDA, GO:0010735=IDA, GO:0051491=IEA, GO:0060292=IEA, GO:0030155=IEA, GO:0042803=IPI, GO:0031175=IEA, GO:1900222=IMP, GO:0001947=ISS, GO:0022028=IEA, GO:0007507=ISS, GO:0048589=IEA, GO:0070830=IEA, GO:0010669=IEA, GO:0055003=IEA, GO:0042789=ISS, GO:0008306=IEA, GO:0001707=IEA, GO:0051150=TAS, GO:0045214=IEA, GO:0009636=TAS, GO:0030168=IEA, GO:0000978=ISS, GO:0001701=IEA, GO:0031490=IEA, GO:0060347=IEA, GO:0035855=IEA, GO:0033561=IEA, GO:0043589=IEA, GO:0090398=IMP, GO:0008134=IPI, GO:0030038=IEA, GO:0035912=IEA, GO:0043149=IEA, GO:0002042=IMP, GO:0005634=IDA, GO:0060261=IDA, GO:0046716=ISS, GO:0005737=TAS, GO:0045987=IDA, GO:0048666=TAS, GO:0061029=IEA, GO:0045944=IDA, GO:0048821=IEA, GO:0009725=IDA, GO:0034097=NAS, GO:0030220=IEA, GO:0090136=IEA, GO:0001666=IEP, GO:0001569=IEA, GO:0002011=IEA, GO:0090009=IEA, GO:0060055=TAS, GO:0001228=ISS, GO:0001829=IDA, GO:0060218=IEA, GO:0045059=IEA, GO:0021766=IEA, GO:0001077=IDA, GO:0001076=IEA, GO:0007160=IEA, GO:0060947=IEA, GO:0001764=IEA, GO:0003257=IGI} angiogenesis involved in wound healing, associative learning, cardiac myofibril assembly, cardiac vascular smooth muscle cell differentiation, cell migration involved in sprouting angiogenesis, cell-matrix adhesion, cellular senescence, contractile actin filament bundle assembly, developmental growth, dorsal aorta morphogenesis, epithelial cell-cell adhesion, epithelial structure maintenance, erythrocyte development, eyelid development in camera-type eye, heart development, heart looping, heart trabecula formation, hematopoietic stem cell differentiation, hippocampus development, in utero embryonic development, long term synaptic depression, mRNA transcription from RNA polymerase II promoter, megakaryocyte development, mesoderm formation, morphogenesis of an epithelial sheet, muscle cell homeostasis, negative regulation of beta-amyloid clearance, neuron development, neuron migration, neuron projection development, patterning of blood vessels, platelet activation, platelet formation, positive regulation of cell differentiation, positive regulation of filopodium assembly, positive regulation of smooth muscle contraction, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation, positive regulation of transcription initiation from RNA polymerase II promoter, positive regulation of transcription via serum response element binding, positive thymic T cell selection, primitive streak formation, regulation of cell adhesion, regulation of smooth muscle cell differentiation, regulation of water loss via skin, response to cytokine stimulus, response to hormone stimulus, response to hypoxia, response to toxic substance, sarcomere organization, skin morphogenesis, stress fiber assembly, tangential migration from the subventricular zone to the olfactory bulb, tight junction assembly, transcription from RNA polymerase II promoter, trophectodermal cell differentiation cytoplasm, nuclear chromatin, nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, RNA polymerase II transcription factor binding transcription factor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, chromatin DNA binding, protein binding, protein homodimerization activity, sequence-specific DNA binding transcription factor activity, serum response element binding, transcription factor binding Human SRFBP1 UniProtKB UniProtKB {GO:0048471=GO_REF:0000039, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q8NEF9 Serum response factor-binding protein 1 protein 20130413 {GO:0048471=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus, perinuclear region of cytoplasm Human UniProtKB-SubCell:SL-0198 SRGAP1 Reactome UniProtKB {GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0016477=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0007264=Reactome:REACT_11044, GO:0017048=GO_REF:0000019, GO:0007266=GO_REF:0000019, GO:0005100=GO_REF:0000019, GO:0005829=Reactome:REACT_19347} Q7Z6B7 SLIT-ROBO Rho GTPase-activating protein 1 protein 20130301 {GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0016477=IEA, GO:0007411=TAS, GO:0007264=TAS, GO:0017048=IEA, GO:0007266=IEA, GO:0005100=IEA, GO:0005829=TAS} Rho protein signal transduction, axon guidance, cell migration, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular Rho GTPase activator activity, Rho GTPase binding Human SRGAP2 ENSEMBL UniProtKB {GO:0005515=PMID:21148482, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000019, GO:0007264=Reactome:REACT_11044, GO:0008283=PMID:20810653, GO:0005743=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0032855=PMID:20810653, GO:0042803=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0051014=PMID:21148482, GO:0005622=GO_REF:0000002, GO:0007411=Reactome:REACT_18266, GO:0045211=GO_REF:0000019, GO:0060548=PMID:20810653, GO:0034446=PMID:20810653, GO:0060996=GO_REF:0000019, GO:0046847=GO_REF:0000019, GO:0030675=GO_REF:0000019, GO:0051056=Reactome:REACT_11051, GO:2001223=PMID:22559944, GO:0003363=PMID:20810653, GO:0014069=GO_REF:0000019, GO:0044327=PMID:22559944, GO:0030027=PMID:20810653, GO:0021816=GO_REF:0000019, GO:0045335=GO_REF:0000019, GO:0048365=GO_REF:0000019, GO:0007165=GO_REF:0000002, GO:0048812=GO_REF:0000019} Q5VZB4 SLIT-ROBO Rho GTPase activating protein 2 protein 20130413 {GO:0005515=IPI, GO:0030054=IEA, GO:0005886=IEA, GO:0007264=TAS, GO:0008283=IMP, GO:0005743=IEA, GO:0005634=IEA, GO:0032855=IMP, GO:0042803=IEA, GO:0005829=IEA, GO:0051014=IDA, GO:0005622=IEA, GO:0007411=TAS, GO:0045211=IEA, GO:0060548=IMP, GO:0034446=IMP, GO:0060996=IEA, GO:0046847=IEA, GO:0030675=IEA, GO:0051056=TAS, GO:2001223=IDA, GO:0003363=IMP, GO:0014069=IEA, GO:0044327=IDA, GO:0030027=IDA, GO:0021816=IEA, GO:0045335=IEA, GO:0048365=IEA, GO:0007165=IEA, GO:0048812=IEA} actin filament severing, axon guidance, cell proliferation, dendritic spine development, extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration, filopodium assembly, lamellipodium assembly involved in ameboidal cell migration, negative regulation of cell death, negative regulation of neuron migration, neuron projection morphogenesis, positive regulation of Rac GTPase activity, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction, substrate adhesion-dependent cell spreading cell junction, cytosol, dendritic spine head, intracellular, lamellipodium, mitochondrial inner membrane, nucleus, phagocytic vesicle, plasma membrane, postsynaptic density, postsynaptic membrane Rac GTPase activator activity, Rac GTPase binding, protein binding, protein homodimerization activity Human Ensembl:ENSMUSP00000095195 SRGAP3 Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0007264=Reactome:REACT_11044, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} O43295 SLIT-ROBO Rho GTPase-activating protein 3 protein 20130301 {GO:0051056=TAS, GO:0007264=TAS, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol GTPase activator activity Human SRGN Reactome UniProtKB {GO:0005515=PMID:11911826, GO:0005794=PMID:15136585, GO:0005518=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0006915=PMID:11911826, GO:0005576=Reactome:REACT_21351, GO:0030502=PMID:16870619, GO:0050710=GO_REF:0000024, GO:0031214=GO_REF:0000037, GO:0005615=PMID:11154222, GO:0042629=GO_REF:0000024, GO:0042588=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0016485=GO_REF:0000024, GO:0002576=Reactome:REACT_318, GO:0033373=GO_REF:0000024, GO:0031093=Reactome:REACT_21351, GO:0033382=GO_REF:0000024, GO:0033364=GO_REF:0000024, GO:0033371=GO_REF:0000024} P10124 Serglycin protein 20080513 {GO:0005515=IPI, GO:0005794=IDA, GO:0005518=IEA, GO:0030168=TAS, GO:0006915=IDA, GO:0005576=TAS, GO:0030502=IDA, GO:0050710=ISS, GO:0031214=IEA, GO:0005615=IDA, GO:0042629=ISS, GO:0042588=IEA, GO:0007596=TAS, GO:0016485=ISS, GO:0002576=TAS, GO:0033373=ISS, GO:0031093=TAS, GO:0033382=ISS, GO:0033364=ISS, GO:0033371=ISS} T cell secretory granule organization, apoptotic process, biomineral tissue development, blood coagulation, maintenance of granzyme B location in T cell secretory granule, maintenance of protease location in mast cell secretory granule, mast cell secretory granule organization, negative regulation of bone mineralization, negative regulation of cytokine secretion, platelet activation, platelet degranulation, protein processing Golgi apparatus, extracellular region, extracellular space, mast cell granule, platelet alpha granule lumen, zymogen granule collagen binding, protein binding Human SRI BHF-UCL UniProtKB {GO:0005515=PMID:9268363, GO:0030018=PMID:12754254, GO:0008016=PMID:9668070, GO:0006942=PMID:9668070, GO:0006880=PMID:9668070, GO:0002020=PMID:10748169, GO:0005829=PMID:10748169, GO:0007507=PMID:9668070, GO:0005737=PMID:16130169, GO:0010649=PMID:17699613, GO:0010880=PMID:17699613, GO:0060315=PMID:17699613, GO:0006810=PMID:9668070, GO:0051924=PMID:17130302, GO:0006816=GO_REF:0000019, GO:0086004=PMID:17130302, GO:0010459=PMID:12754254, GO:0005246=PMID:9668070, GO:0005509=PMID:17215369, GO:0005102=PMID:9668070, GO:0033017=GO_REF:0000039, GO:0030315=PMID:17699613, GO:1901844=PMID:17130302, GO:0044325=PMID:12754254, GO:0007165=PMID:16130169, GO:0016529=PMID:17699613, GO:0007517=PMID:9668070, GO:0042584=PMID:9268363, GO:0016020=PMID:10748169, GO:0005789=PMID:10672515, GO:0001508=PMID:9668070} P30626 Sorcin protein 20130128 {GO:0005515=IPI, GO:0030018=IDA, GO:0008016=TAS, GO:0006942=TAS, GO:0006880=TAS, GO:0002020=IPI, GO:0005829=IDA, GO:0007507=TAS, GO:0005737=TAS, GO:0010649=TAS, GO:0010880=TAS, GO:0060315=IDA, GO:0006810=TAS, GO:0051924=IMP, GO:0006816=IEA, GO:0086004=IMP, GO:0010459=IMP, GO:0005246=TAS, GO:0005509=IDA, GO:0005102=TAS, GO:0033017=IEA, GO:0030315=TAS, GO:1901844=IMP, GO:0044325=TAS, GO:0007165=TAS, GO:0016529=TAS, GO:0007517=TAS, GO:0042584=IDA, GO:0016020=IDA, GO:0005789=IDA, GO:0001508=TAS} calcium ion transport, heart development, intracellular sequestering of iron ion, muscle organ development, negative regulation of heart rate, negative regulation of ryanodine-sensitive calcium-release channel activity, regulation of action potential, regulation of calcium ion transport, regulation of cardiac muscle cell contraction, regulation of cell communication by electrical coupling, regulation of cell communication by electrical coupling involved in cardiac conduction, regulation of heart contraction, regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum, regulation of striated muscle contraction, signal transduction, transport T-tubule, Z disc, chromaffin granule membrane, cytoplasm, cytosol, endoplasmic reticulum membrane, membrane, sarcoplasmic reticulum, sarcoplasmic reticulum membrane calcium channel regulator activity, calcium ion binding, ion channel binding, protease binding, protein binding, receptor binding colocalizes_with Human SRM Reactome UniProtKB {GO:0008295=PMID:17585781, GO:0034641=Reactome:REACT_13, GO:0004766=PMID:17585781, GO:0006595=Reactome:REACT_14820, GO:0044281=Reactome:REACT_111217, GO:0003824=GO_REF:0000002, GO:0042803=PMID:17585781, GO:0016740=GO_REF:0000038, GO:0005829=Reactome:REACT_14788} P19623 Spermidine synthase protein 20130301 {GO:0008295=IDA, GO:0034641=TAS, GO:0004766=IDA, GO:0006595=TAS, GO:0044281=TAS, GO:0003824=IEA, GO:0042803=IDA, GO:0016740=IEA, GO:0005829=TAS} cellular nitrogen compound metabolic process, polyamine metabolic process, small molecule metabolic process, spermidine biosynthetic process cytosol catalytic activity, protein homodimerization activity, spermidine synthase activity, transferase activity Human SRMS UniProtKB UniProtKB {GO:0004715=GO_REF:0000003, GO:0005524=GO_REF:0000037} Q9H3Y6 Tyrosine-protein kinase Srms protein 20130413 {GO:0004715=IEA, GO:0005524=IEA} ATP binding, non-membrane spanning protein tyrosine kinase activity Human EC:2.7.10.2 SRP14 Reactome UniProtKB {GO:0005786=PMID:18089836, GO:0010467=Reactome:REACT_71, GO:0006614=Reactome:REACT_115902, GO:0030942=GO_REF:0000002, GO:0042493=PMID:18089836, GO:0003723=PMID:2557625, GO:0008312=GO_REF:0000002, GO:0006613=PMID:2557625, GO:0045047=PMID:18089836, GO:0006412=Reactome:REACT_1014, GO:0005829=Reactome:REACT_115921, GO:0005737=PMID:8196634, GO:0044267=Reactome:REACT_17015} P37108 Signal recognition particle 14 kDa protein protein 20130213 {GO:0005786=IDA, GO:0010467=TAS, GO:0006614=TAS, GO:0030942=IEA, GO:0042493=IDA, GO:0003723=TAS, GO:0008312=IEA, GO:0006613=TAS, GO:0045047=IMP, GO:0006412=TAS, GO:0005829=TAS, GO:0005737=TAS, GO:0044267=TAS} SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, cotranslational protein targeting to membrane, gene expression, protein targeting to ER, response to drug, translation cytoplasm, cytosol, signal recognition particle, endoplasmic reticulum targeting 7S RNA binding, RNA binding, endoplasmic reticulum signal peptide binding Human SRP19 HPA UniProtKB {GO:0005786=PMID:18089836, GO:0010467=Reactome:REACT_71, GO:0006614=Reactome:REACT_115902, GO:0042493=PMID:18089836, GO:0008312=PMID:17434535, GO:0006613=PMID:1678319, GO:0005730=PMID:10618370, GO:0005634=GO_REF:0000052, GO:0006412=Reactome:REACT_1014, GO:0005829=Reactome:REACT_115921, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0048500=GO_REF:0000002, GO:0044267=Reactome:REACT_17015} P09132 Signal recognition particle 19 kDa protein protein 20101115 {GO:0005786=IDA, GO:0010467=TAS, GO:0006614=TAS, GO:0042493=IDA, GO:0008312=IDA, GO:0006613=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0006412=TAS, GO:0005829=TAS, GO:0005739=IDA, GO:0005737=IDA, GO:0048500=IEA, GO:0044267=TAS} SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, cotranslational protein targeting to membrane, gene expression, response to drug, translation cytoplasm, cytosol, mitochondrion, nucleolus, nucleus, signal recognition particle, signal recognition particle, endoplasmic reticulum targeting 7S RNA binding Human SRP54 GOC UniProtKB {GO:0005786=PMID:18089836, GO:0010467=Reactome:REACT_71, GO:0006617=GO_REF:0000024, GO:0006616=GO_REF:0000024, GO:0042493=PMID:18089836, GO:0006614=Reactome:REACT_115902, GO:0030942=PMID:9511762, GO:0008312=PMID:9511762, GO:0005730=GO_REF:0000052, GO:0003924=PMID:8247130, GO:0005634=PMID:18089836, GO:0005525=PMID:8622769, GO:0006412=Reactome:REACT_1014, GO:0045047=PMID:18089836, GO:0005829=Reactome:REACT_115921, GO:0006184=PMID:8247130, GO:0005737=GO_REF:0000052, GO:0016607=GO_REF:0000039, GO:0008144=PMID:18089836, GO:0043021=PMID:9511762, GO:0048500=GO_REF:0000002, GO:0019003=PMID:8622769, GO:0044267=Reactome:REACT_17015} P61011 Signal recognition particle 54 kDa protein protein 20130413 {GO:0005786=IDA, GO:0010467=TAS, GO:0006617=ISS, GO:0006616=ISS, GO:0042493=IDA, GO:0006614=TAS, GO:0030942=IDA, GO:0008312=IDA, GO:0005730=IDA, GO:0003924=IDA, GO:0005634=IDA, GO:0005525=IDA, GO:0006412=TAS, GO:0045047=IMP, GO:0005829=TAS, GO:0006184=IDA, GO:0005737=IDA, GO:0016607=IEA, GO:0008144=IDA, GO:0043021=IDA, GO:0048500=IEA, GO:0019003=IDA, GO:0044267=TAS} GTP catabolic process, SRP-dependent cotranslational protein targeting to membrane, SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition, SRP-dependent cotranslational protein targeting to membrane, translocation, cellular protein metabolic process, gene expression, protein targeting to ER, response to drug, translation cytoplasm, cytosol, nuclear speck, nucleolus, nucleus, signal recognition particle, signal recognition particle, endoplasmic reticulum targeting 7S RNA binding, GDP binding, GTP binding, GTPase activity, drug binding, endoplasmic reticulum signal peptide binding, ribonucleoprotein complex binding Human SRP68 HPA UniProtKB {GO:0005786=PMID:18089836, GO:0010467=Reactome:REACT_71, GO:0005783=PMID:10618370, GO:0006614=Reactome:REACT_115902, GO:0030942=GO_REF:0000002, GO:0042493=PMID:18089836, GO:0008312=GO_REF:0000002, GO:0005730=GO_REF:0000039, GO:0006412=Reactome:REACT_1014, GO:0005829=Reactome:REACT_115921, GO:0005737=GO_REF:0000052, GO:0005840=PMID:10618370, GO:0005047=PMID:17254600, GO:0044267=Reactome:REACT_17015} Q9UHB9 Signal recognition particle subunit SRP68 protein 20100326 {GO:0005786=IDA, GO:0010467=TAS, GO:0005783=TAS, GO:0006614=TAS, GO:0030942=IEA, GO:0042493=IDA, GO:0008312=IEA, GO:0005730=IEA, GO:0006412=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0005840=TAS, GO:0005047=IPI, GO:0044267=TAS} SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, response to drug, translation cytoplasm, cytosol, endoplasmic reticulum, nucleolus, ribosome, signal recognition particle, endoplasmic reticulum targeting 7S RNA binding, endoplasmic reticulum signal peptide binding, signal recognition particle binding Human SRP72 HPA UniProtKB {GO:0005786=PMID:18089836, GO:0010467=Reactome:REACT_71, GO:0005886=GO_REF:0000052, GO:0005783=PMID:22541560, GO:0006614=Reactome:REACT_115902, GO:0042493=PMID:18089836, GO:0008312=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0006412=Reactome:REACT_1014, GO:0005829=Reactome:REACT_115921, GO:0005737=GO_REF:0000052, GO:0005047=PMID:17254600, GO:0044267=Reactome:REACT_17015} O76094 Signal recognition particle subunit SRP72 protein 20101115 {GO:0005786=IDA, GO:0010467=TAS, GO:0005886=IDA, GO:0005783=IDA, GO:0006614=TAS, GO:0042493=IDA, GO:0008312=IEA, GO:0005730=IDA, GO:0006412=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0005047=IPI, GO:0044267=TAS} SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, response to drug, translation cytoplasm, cytosol, endoplasmic reticulum, nucleolus, plasma membrane, signal recognition particle, endoplasmic reticulum targeting 7S RNA binding, signal recognition particle binding Human SRP9 Reactome UniProtKB {GO:0005786=PMID:17154533, GO:0010467=Reactome:REACT_71, GO:0005785=PMID:7730321, GO:0003723=PMID:7730321, GO:0006614=Reactome:REACT_115902, GO:0008312=GO_REF:0000002, GO:0048500=GO_REF:0000002, GO:0005047=PMID:7730321, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0005829=Reactome:REACT_115921, GO:0045900=GO_REF:0000002} P49458 Signal recognition particle 9 kDa protein protein 20130213 {GO:0005786=NAS, GO:0010467=TAS, GO:0005785=TAS, GO:0003723=TAS, GO:0006614=TAS, GO:0008312=IEA, GO:0048500=IEA, GO:0005047=TAS, GO:0044267=TAS, GO:0006412=TAS, GO:0005829=TAS, GO:0045900=IEA} SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, negative regulation of translational elongation, translation cytosol, signal recognition particle, signal recognition particle receptor complex, signal recognition particle, endoplasmic reticulum targeting 7S RNA binding, RNA binding, signal recognition particle binding Human SRPK1 HPA UniProtKB {GO:0005515=PMID:11509566, GO:0006397=GO_REF:0000037, GO:0008380=GO_REF:0000037, GO:0048024=PMID:21205200, GO:0000287=PMID:11509566, GO:0005783=GO_REF:0000037, GO:0005634=PMID:11509566, GO:0050684=PMID:8208298, GO:0005524=PMID:11509566, GO:0007243=PMID:11509566, GO:0016363=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0007059=PMID:15034300, GO:0004672=PMID:8208298, GO:0004674=PMID:9237760, GO:0045087=PMID:12417631, GO:0019048=GO_REF:0000037, GO:0006468=PMID:9237760, GO:0035092=PMID:21205200, GO:0045070=PMID:20498328, GO:0045071=PMID:12417631} Q96SB4 SRSF protein kinase 1 protein 20090616 {GO:0005515=IPI, GO:0006397=IEA, GO:0008380=IEA, GO:0048024=TAS, GO:0000287=IDA, GO:0005783=IEA, GO:0005634=IDA, GO:0050684=IDA, GO:0005524=IDA, GO:0007243=IDA, GO:0016363=IEA, GO:0005737=IDA, GO:0007059=IDA, GO:0004672=TAS, GO:0004674=IDA, GO:0045087=IC, GO:0019048=IEA, GO:0006468=IDA, GO:0035092=TAS, GO:0045070=IDA, GO:0045071=IDA} RNA splicing, chromosome segregation, innate immune response, intracellular protein kinase cascade, mRNA processing, negative regulation of viral genome replication, positive regulation of viral genome replication, protein phosphorylation, regulation of mRNA processing, regulation of mRNA splicing, via spliceosome, sperm chromatin condensation, virus-host interaction cytoplasm, endoplasmic reticulum, nuclear matrix, nucleus ATP binding, magnesium ion binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human SRPK2 HPA UniProtKB {GO:0008380=PMID:9472028, GO:0000245=PMID:9472028, GO:0008284=PMID:18559500, GO:0048024=PMID:21205200, GO:0000287=PMID:9472028, GO:0005730=GO_REF:0000052, GO:0035063=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0001525=GO_REF:0000024, GO:0045787=GO_REF:0000024, GO:0005524=PMID:9472028, GO:0030154=GO_REF:0000037, GO:0007243=PMID:9472028, GO:0010628=GO_REF:0000024, GO:0071889=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0043525=GO_REF:0000024, GO:0004672=GO_REF:0000002, GO:0004674=PMID:9472028, GO:0045087=PMID:12417631, GO:0006468=PMID:9472028, GO:0045070=PMID:20498328, GO:0045071=PMID:12417631, GO:0016772=GO_REF:0000002} P78362 SRSF protein kinase 2 protein 20090616 {GO:0008380=IDA, GO:0000245=IDA, GO:0008284=IDA, GO:0048024=TAS, GO:0000287=IDA, GO:0005730=IDA, GO:0035063=ISS, GO:0005634=IDA, GO:0001525=ISS, GO:0045787=ISS, GO:0005524=IDA, GO:0030154=IEA, GO:0007243=IDA, GO:0010628=ISS, GO:0071889=ISS, GO:0005737=IDA, GO:0043525=ISS, GO:0004672=IEA, GO:0004674=IDA, GO:0045087=IC, GO:0006468=IDA, GO:0045070=IDA, GO:0045071=IDA, GO:0016772=IEA} RNA splicing, angiogenesis, cell differentiation, innate immune response, intracellular protein kinase cascade, negative regulation of viral genome replication, nuclear speck organization, positive regulation of cell cycle, positive regulation of cell proliferation, positive regulation of gene expression, positive regulation of neuron apoptotic process, positive regulation of viral genome replication, protein phosphorylation, regulation of mRNA splicing, via spliceosome, spliceosomal complex assembly cytoplasm, nucleolus, nucleus 14-3-3 protein binding, ATP binding, magnesium ion binding, protein kinase activity, protein serine/threonine kinase activity, transferase activity, transferring phosphorus-containing groups Human SRPK3 UniProtKB UniProtKB {GO:0004672=GO_REF:0000002, GO:0007519=GO_REF:0000019, GO:0004674=GO_REF:0000029, GO:0060537=GO_REF:0000024, GO:0006468=GO_REF:0000029, GO:0005575=GO_REF:0000015, GO:0005524=GO_REF:0000029, GO:0030154=GO_REF:0000037} Q9UPE1 SRSF protein kinase 3 protein 20110224 {GO:0004672=IEA, GO:0007519=IEA, GO:0004674=NAS, GO:0060537=ISS, GO:0006468=NAS, GO:0005575=ND, GO:0005524=NAS, GO:0030154=IEA} cell differentiation, muscle tissue development, protein phosphorylation, skeletal muscle tissue development cellular_component ATP binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB:Q9Z0G2 SRPR Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0005785=GO_REF:0000002, GO:0005783=PMID:2827661, GO:0006614=Reactome:REACT_115902, GO:0006613=PMID:2827661, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0006412=Reactome:REACT_1014, GO:0030968=Reactome:REACT_18356, GO:0005789=Reactome:REACT_116080, GO:0005047=GO_REF:0000002, GO:0016021=PMID:2827661, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015} P08240 Signal recognition particle receptor subunit alpha protein 20130213 {GO:0010467=TAS, GO:0005785=IEA, GO:0005783=TAS, GO:0006614=TAS, GO:0006613=TAS, GO:0003924=IEA, GO:0005525=IEA, GO:0006412=TAS, GO:0030968=TAS, GO:0005789=TAS, GO:0005047=IEA, GO:0016021=TAS, GO:0006987=TAS, GO:0044267=TAS} SRP-dependent cotranslational protein targeting to membrane, activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, cotranslational protein targeting to membrane, endoplasmic reticulum unfolded protein response, gene expression, translation endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, signal recognition particle receptor complex GTP binding, GTPase activity, signal recognition particle binding Human SRPRB Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0005881=PMID:23264731, GO:0005737=PMID:19664239, GO:0007264=GO_REF:0000002, GO:0006614=Reactome:REACT_115902, GO:0005789=Reactome:REACT_115588, GO:0016021=GO_REF:0000037, GO:0006987=Reactome:REACT_18368, GO:0005525=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0030968=Reactome:REACT_18356} Q9Y5M8 Signal recognition particle receptor subunit beta protein 20130213 {GO:0010467=TAS, GO:0005881=IDA, GO:0005737=IDA, GO:0007264=IEA, GO:0006614=TAS, GO:0005789=TAS, GO:0016021=IEA, GO:0006987=TAS, GO:0005525=IEA, GO:0044267=TAS, GO:0006412=TAS, GO:0030968=TAS} SRP-dependent cotranslational protein targeting to membrane, activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, gene expression, small GTPase mediated signal transduction, translation cytoplasm, cytoplasmic microtubule, endoplasmic reticulum membrane, integral to membrane GTP binding Human SRPX PINC UniProtKB {GO:0043065=GO_REF:0000019, GO:0005776=GO_REF:0000019, GO:0016020=PMID:8634708, GO:0009986=PMID:12493773, GO:0005783=GO_REF:0000019, GO:0060244=GO_REF:0000019, GO:0006914=GO_REF:0000019, GO:0033554=GO_REF:0000019, GO:0001845=GO_REF:0000019, GO:0007155=GO_REF:0000037} P78539 Sushi repeat-containing protein SRPX protein 20030904 {GO:0043065=IEA, GO:0005776=IEA, GO:0016020=TAS, GO:0009986=IDA, GO:0005783=IEA, GO:0060244=IEA, GO:0006914=IEA, GO:0033554=IEA, GO:0001845=IEA, GO:0007155=IEA} autophagy, cell adhesion, cellular response to stress, negative regulation of cell proliferation involved in contact inhibition, phagolysosome assembly, positive regulation of apoptotic process autophagic vacuole, cell surface, endoplasmic reticulum, membrane Human SRPX2 HPA UniProtKB {GO:0005515=PMID:18718938, GO:0042325=PMID:19065654, GO:0005737=PMID:19065654, GO:0016337=PMID:19065654, GO:0048870=PMID:19065654, GO:0015630=GO_REF:0000052, GO:0005102=PMID:18718938, GO:0090050=GO_REF:0000024, GO:0005576=GO_REF:0000039, GO:0001525=GO_REF:0000037} O60687 Sushi repeat-containing protein SRPX2 protein 20110516 {GO:0005515=IPI, GO:0042325=IDA, GO:0005737=IDA, GO:0016337=IDA, GO:0048870=IDA, GO:0015630=IDA, GO:0005102=IPI, GO:0090050=ISS, GO:0005576=IEA, GO:0001525=IEA} angiogenesis, cell motility, cell-cell adhesion, positive regulation of cell migration involved in sprouting angiogenesis, regulation of phosphorylation cytoplasm, extracellular region, microtubule cytoskeleton protein binding, receptor binding Human SRR UniProtKB UniProtKB {GO:0070178=PMID:20106978, GO:0005886=GO_REF:0000019, GO:0009069=GO_REF:0000024, GO:0042803=PMID:20106978, GO:0070179=PMID:15193426, GO:0008721=GO_REF:0000003, GO:0003941=PMID:18812225, GO:0005737=PMID:16314870, GO:0051289=GO_REF:0000024, GO:0030378=PMID:20106978, GO:0032496=PMID:15681805, GO:0043025=PMID:17880399, GO:0042866=PMID:18812225, GO:0006520=GO_REF:0000002, GO:0000287=PMID:20106978, GO:0042493=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0005509=GO_REF:0000024, GO:0045177=GO_REF:0000019, GO:0043278=GO_REF:0000019, GO:0030165=PMID:16314870, GO:0005524=PMID:20106978, GO:0018114=GO_REF:0000024, GO:0007420=GO_REF:0000019, GO:0030170=PMID:20106978, GO:0016594=GO_REF:0000024, GO:0006563=PMID:20106978} Q9GZT4 Serine racemase protein 20101221 {GO:0070178=IDA, GO:0005886=IEA, GO:0009069=ISS, GO:0042803=IPI, GO:0070179=IDA, GO:0008721=IEA, GO:0003941=IDA, GO:0005737=IDA, GO:0051289=ISS, GO:0030378=IDA, GO:0032496=IEP, GO:0043025=IDA, GO:0042866=IDA, GO:0006520=IEA, GO:0000287=IDA, GO:0042493=IEA, GO:0007568=IEA, GO:0005509=ISS, GO:0045177=IEA, GO:0043278=IEA, GO:0030165=IPI, GO:0005524=IDA, GO:0018114=ISS, GO:0007420=IEA, GO:0030170=IDA, GO:0016594=ISS, GO:0006563=IDA} D-serine biosynthetic process, D-serine metabolic process, L-serine metabolic process, aging, brain development, cellular amino acid metabolic process, protein homotetramerization, pyruvate biosynthetic process, response to drug, response to lipopolysaccharide, response to morphine, serine family amino acid metabolic process apical part of cell, cytoplasm, neuronal cell body, plasma membrane ATP binding, D-serine ammonia-lyase activity, L-serine ammonia-lyase activity, PDZ domain binding, calcium ion binding, glycine binding, magnesium ion binding, protein homodimerization activity, pyridoxal phosphate binding, serine racemase activity, threonine racemase activity Human SRRM1 Reactome UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0006397=GO_REF:0000002, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0006366=Reactome:REACT_1366, GO:0003723=GO_REF:0000037, GO:0031124=Reactome:REACT_1849, GO:0005634=PMID:9531537, GO:0071013=PMID:11991638, GO:0003677=GO_REF:0000037, GO:0016363=GO_REF:0000039, GO:0005829=Reactome:REACT_2104, GO:0006406=Reactome:REACT_1597, GO:0016607=GO_REF:0000039, GO:0000398=Reactome:REACT_467, GO:0000375=PMID:9531537, GO:0005654=Reactome:REACT_2104} Q8IYB3 Serine/arginine repetitive matrix protein 1 protein 20130213 {GO:0008380=TAS, GO:0006397=IEA, GO:0010467=TAS, GO:0006369=TAS, GO:0006366=TAS, GO:0003723=IEA, GO:0031124=TAS, GO:0005634=TAS, GO:0071013=IDA, GO:0003677=IEA, GO:0016363=IEA, GO:0005829=TAS, GO:0006406=TAS, GO:0016607=IEA, GO:0000398=TAS, GO:0000375=TAS, GO:0005654=TAS} RNA splicing, RNA splicing, via transesterification reactions, gene expression, mRNA 3'-end processing, mRNA export from nucleus, mRNA processing, mRNA splicing, via spliceosome, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter catalytic step 2 spliceosome, cytosol, nuclear matrix, nuclear speck, nucleoplasm, nucleus DNA binding, RNA binding Human SRRM2 HPA UniProtKB {GO:0015030=PMID:17577209, GO:0047485=PMID:17577209, GO:0016607=PMID:17577209, GO:0000398=PMID:11991638, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0070742=PMID:17577209, GO:0071013=PMID:11991638} Q9UQ35 Serine/arginine repetitive matrix protein 2 protein 20111111 {GO:0015030=IDA, GO:0047485=IPI, GO:0016607=IDA, GO:0000398=IC, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0070742=IDA, GO:0071013=IDA} mRNA splicing, via spliceosome Cajal body, catalytic step 2 spliceosome, nuclear speck, nucleolus, nucleus C2H2 zinc finger domain binding, RNA binding, protein N-terminus binding NOT Human SRRM4 UniProtKB UniProtKB {GO:0006397=GO_REF:0000024, GO:0008380=GO_REF:0000037, GO:0005634=GO_REF:0000024, GO:0043484=GO_REF:0000024, GO:0003729=GO_REF:0000024, GO:0030154=GO_REF:0000024, GO:0007399=GO_REF:0000024} A7MD48 Serine/arginine repetitive matrix protein 4 protein 20091012 {GO:0006397=ISS, GO:0008380=IEA, GO:0005634=ISS, GO:0043484=ISS, GO:0003729=ISS, GO:0030154=ISS, GO:0007399=ISS} RNA splicing, cell differentiation, mRNA processing, nervous system development, regulation of RNA splicing nucleus mRNA binding Human UniProtKB:Q8BKA3 SRRT UniProtKB UniProtKB {GO:0005515=PMID:20858735, GO:0097150=GO_REF:0000024, GO:0006355=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0046685=PMID:11239002, GO:0008283=GO_REF:0000024, GO:0031053=PMID:19632182, GO:0005654=GO_REF:0000024, GO:0003677=GO_REF:0000024, GO:0006351=GO_REF:0000037} Q9BXP5 Serrate RNA effector molecule homolog protein 20090811 {GO:0005515=IPI, GO:0097150=ISS, GO:0006355=ISS, GO:0005737=ISS, GO:0046685=NAS, GO:0008283=ISS, GO:0031053=IMP, GO:0005654=ISS, GO:0003677=ISS, GO:0006351=IEA} cell proliferation, neuronal stem cell maintenance, primary miRNA processing, regulation of transcription, DNA-dependent, response to arsenic-containing substance, transcription, DNA-dependent cytoplasm, nucleoplasm DNA binding, protein binding Human UniProtKB:Q99MR6 SRSF1 IntAct UniProtKB {GO:0006397=PMID:1830244, GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:21988832, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0006366=Reactome:REACT_1366, GO:0003723=PMID:20797886, GO:0006376=PMID:1830244, GO:0031124=Reactome:REACT_1849, GO:0050733=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0071013=PMID:11991638, GO:0001701=GO_REF:0000019, GO:0060048=GO_REF:0000019, GO:0000395=PMID:9885563, GO:0005737=GO_REF:0000039, GO:0006406=Reactome:REACT_1597, GO:0000166=GO_REF:0000002, GO:0016607=PMID:20797886, GO:0000398=Reactome:REACT_1753, GO:0005654=Reactome:REACT_2241} Q07955 Serine/arginine-rich splicing factor 1 protein 20130415 {GO:0006397=TAS, GO:0008380=TAS, GO:0005515=IPI, GO:0010467=TAS, GO:0006369=TAS, GO:0006366=TAS, GO:0003723=IPI, GO:0006376=TAS, GO:0031124=TAS, GO:0050733=IEA, GO:0003676=IEA, GO:0071013=IDA, GO:0001701=IEA, GO:0060048=IEA, GO:0000395=IDA, GO:0005737=IEA, GO:0006406=TAS, GO:0000166=IEA, GO:0016607=IDA, GO:0000398=TAS, GO:0005654=TAS} RNA splicing, cardiac muscle contraction, gene expression, in utero embryonic development, mRNA 3'-end processing, mRNA 5'-splice site recognition, mRNA export from nucleus, mRNA processing, mRNA splice site selection, mRNA splicing, via spliceosome, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter catalytic step 2 spliceosome, cytoplasm, nuclear speck, nucleoplasm RNA binding, RS domain binding, nucleic acid binding, nucleotide binding, protein binding Human UniProtKB:Q9UBU9 SRSF10 InterPro UniProtKB {GO:0005515=PMID:9774382, GO:0000244=PMID:11684676, GO:0006355=PMID:9774382, GO:0048025=PMID:11684676, GO:0003723=PMID:9774382, GO:0006376=PMID:9774382, GO:0005634=PMID:9774382, GO:0050733=PMID:11684676, GO:0003676=GO_REF:0000002, GO:0005737=PMID:11684676, GO:0006406=PMID:11684676, GO:0000166=GO_REF:0000002, GO:0016607=GO_REF:0000039, GO:0000398=PMID:9774382, GO:0000375=PMID:9774382, GO:0016482=PMID:11684676, GO:0005654=PMID:11684676, GO:0051082=PMID:11684676} Q5JRI1 Serine/arginine-rich-splicing factor 10 protein 20130413 {GO:0005515=IPI, GO:0000244=NAS, GO:0006355=NAS, GO:0048025=IDA, GO:0003723=NAS, GO:0006376=IDA, GO:0005634=IC, GO:0050733=NAS, GO:0003676=IEA, GO:0005737=NAS, GO:0006406=NAS, GO:0000166=IEA, GO:0016607=IEA, GO:0000398=IDA, GO:0000375=IDA, GO:0016482=IDA, GO:0005654=IDA, GO:0051082=NAS} RNA splicing, via transesterification reactions, assembly of spliceosomal tri-snRNP, cytoplasmic transport, mRNA export from nucleus, mRNA splice site selection, mRNA splicing, via spliceosome, negative regulation of mRNA splicing, via spliceosome, regulation of transcription, DNA-dependent cytoplasm, nuclear speck, nucleoplasm, nucleus RNA binding, RS domain binding, nucleic acid binding, nucleotide binding, protein binding, unfolded protein binding Human InterPro:IPR000504 SRSF11 HPA UniProtKB {GO:0006397=PMID:1896467, GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:21988832, GO:0006369=Reactome:REACT_894, GO:0010467=Reactome:REACT_71, GO:0006366=Reactome:REACT_1366, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0031124=Reactome:REACT_1849, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0006406=Reactome:REACT_1597, GO:0000166=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0005654=Reactome:REACT_1935} Q5T760 Serine/arginine-rich-splicing factor 11 protein 20080205 {GO:0006397=TAS, GO:0008380=TAS, GO:0005515=IPI, GO:0006369=TAS, GO:0010467=TAS, GO:0006366=TAS, GO:0003723=IEA, GO:0005730=IDA, GO:0031124=TAS, GO:0005634=IDA, GO:0003676=IEA, GO:0006406=TAS, GO:0000166=IEA, GO:0000398=TAS, GO:0005654=TAS} RNA splicing, gene expression, mRNA 3'-end processing, mRNA export from nucleus, mRNA processing, mRNA splicing, via spliceosome, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter nucleolus, nucleoplasm, nucleus RNA binding, nucleic acid binding, nucleotide binding, protein binding NOT Human SRSF12 UniProtKB UniProtKB {GO:0000395=PMID:11684676, GO:0000244=PMID:11684676, GO:0048025=PMID:11684676, GO:0000166=GO_REF:0000002, GO:0000381=PMID:11684676, GO:0003723=PMID:11684676, GO:0016482=PMID:11684676, GO:0005654=PMID:11684676, GO:0051082=PMID:11684676, GO:0050733=PMID:11684676} Q8WXF0 Serine/arginine-rich splicing factor 12 protein 20031216 {GO:0000395=IDA, GO:0000244=NAS, GO:0048025=ISS, GO:0000166=IEA, GO:0000381=IDA, GO:0003723=NAS, GO:0016482=ISS, GO:0005654=ISS, GO:0051082=NAS, GO:0050733=NAS} assembly of spliceosomal tri-snRNP, cytoplasmic transport, mRNA 5'-splice site recognition, negative regulation of mRNA splicing, via spliceosome, regulation of alternative mRNA splicing, via spliceosome nucleoplasm RNA binding, RS domain binding, nucleotide binding, unfolded protein binding Human SRSF2 Reactome UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:9447963, GO:0006397=PMID:8530103, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0006366=Reactome:REACT_1366, GO:0003723=GO_REF:0000037, GO:0003714=PMID:15652350, GO:0031124=Reactome:REACT_1849, GO:0005634=PMID:21653549, GO:0003676=GO_REF:0000002, GO:0006406=Reactome:REACT_1597, GO:0000166=GO_REF:0000002, GO:0016607=PMID:15798186, GO:0000398=Reactome:REACT_1753, GO:0016605=PMID:15652350, GO:0005681=GO_REF:0000019, GO:0005654=Reactome:REACT_2241} Q01130 Serine/arginine-rich splicing factor 2 protein 20130213 {GO:0008380=TAS, GO:0005515=IPI, GO:0006397=TAS, GO:0010467=TAS, GO:0006369=TAS, GO:0006366=TAS, GO:0003723=IEA, GO:0003714=NAS, GO:0031124=TAS, GO:0005634=IDA, GO:0003676=IEA, GO:0006406=TAS, GO:0000166=IEA, GO:0016607=IDA, GO:0000398=TAS, GO:0016605=IDA, GO:0005681=IEA, GO:0005654=TAS} RNA splicing, gene expression, mRNA 3'-end processing, mRNA export from nucleus, mRNA processing, mRNA splicing, via spliceosome, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter PML body, nuclear speck, nucleoplasm, nucleus, spliceosomal complex RNA binding, nucleic acid binding, nucleotide binding, protein binding, transcription corepressor activity Human SRSF3 IntAct UniProtKB {GO:0005515=PMID:14559993, GO:0008380=Reactome:REACT_1735, GO:0006369=Reactome:REACT_894, GO:0010467=Reactome:REACT_71, GO:0006366=Reactome:REACT_1366, GO:0003723=GO_REF:0000037, GO:0031124=Reactome:REACT_1849, GO:0006406=Reactome:REACT_1597, GO:0000166=GO_REF:0000002, GO:0016607=GO_REF:0000019, GO:0043274=GO_REF:0000019, GO:0000398=Reactome:REACT_467, GO:0005654=Reactome:REACT_1935} P84103 Serine/arginine-rich splicing factor 3 protein 20130415 {GO:0005515=IPI, GO:0008380=TAS, GO:0006369=TAS, GO:0010467=TAS, GO:0006366=TAS, GO:0003723=IEA, GO:0031124=TAS, GO:0006406=TAS, GO:0000166=IEA, GO:0016607=IEA, GO:0043274=IEA, GO:0000398=TAS, GO:0005654=TAS} RNA splicing, gene expression, mRNA 3'-end processing, mRNA export from nucleus, mRNA splicing, via spliceosome, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter nuclear speck, nucleoplasm RNA binding, nucleotide binding, phospholipase binding, protein binding Human UniProtKB:Q9JKL7 SRSF4 Reactome UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0006397=PMID:8321209, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0048025=PMID:15009664, GO:0006366=Reactome:REACT_1366, GO:0003723=GO_REF:0000037, GO:0031124=Reactome:REACT_1849, GO:0005634=PMID:8321209, GO:0003676=GO_REF:0000002, GO:0006406=Reactome:REACT_1597, GO:0000166=GO_REF:0000002, GO:0016607=GO_REF:0000039, GO:0000398=Reactome:REACT_467, GO:0000375=PMID:8321209, GO:0005654=Reactome:REACT_1935} Q08170 Serine/arginine-rich splicing factor 4 protein 20130213 {GO:0008380=TAS, GO:0006397=TAS, GO:0010467=TAS, GO:0006369=TAS, GO:0048025=IDA, GO:0006366=TAS, GO:0003723=IEA, GO:0031124=TAS, GO:0005634=TAS, GO:0003676=IEA, GO:0006406=TAS, GO:0000166=IEA, GO:0016607=IEA, GO:0000398=TAS, GO:0000375=TAS, GO:0005654=TAS} RNA splicing, RNA splicing, via transesterification reactions, gene expression, mRNA 3'-end processing, mRNA export from nucleus, mRNA processing, mRNA splicing, via spliceosome, negative regulation of mRNA splicing, via spliceosome, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter nuclear speck, nucleoplasm, nucleus RNA binding, nucleic acid binding, nucleotide binding Human SRSF5 HPA UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0006397=PMID:7556075, GO:0005515=PMID:12762840, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0006366=Reactome:REACT_1366, GO:0003723=GO_REF:0000037, GO:0006376=PMID:7556075, GO:0031124=Reactome:REACT_1849, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0006406=Reactome:REACT_1597, GO:0000166=GO_REF:0000002, GO:0016607=GO_REF:0000024, GO:0000398=Reactome:REACT_467, GO:0051726=GO_REF:0000019, GO:0005654=Reactome:REACT_1935} Q13243 Serine/arginine-rich splicing factor 5 protein 20110516 {GO:0008380=TAS, GO:0006397=TAS, GO:0005515=IPI, GO:0010467=TAS, GO:0006369=TAS, GO:0006366=TAS, GO:0003723=IEA, GO:0006376=TAS, GO:0031124=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0005737=IDA, GO:0006406=TAS, GO:0000166=IEA, GO:0016607=ISS, GO:0000398=TAS, GO:0051726=IEA, GO:0005654=TAS} RNA splicing, gene expression, mRNA 3'-end processing, mRNA export from nucleus, mRNA processing, mRNA splice site selection, mRNA splicing, via spliceosome, regulation of cell cycle, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter cytoplasm, nuclear speck, nucleolus, nucleoplasm, nucleus RNA binding, nucleic acid binding, nucleotide binding, protein binding Human SRSF6 HPA UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0006369=Reactome:REACT_894, GO:0010467=Reactome:REACT_71, GO:0048025=PMID:15009664, GO:0006366=Reactome:REACT_1366, GO:0003723=GO_REF:0000037, GO:0006376=PMID:7556075, GO:0005730=GO_REF:0000052, GO:0031124=Reactome:REACT_1849, GO:0005634=GO_REF:0000052, GO:0006406=Reactome:REACT_1597, GO:0000166=GO_REF:0000002, GO:0000398=Reactome:REACT_1753, GO:0005654=Reactome:REACT_2241} Q13247 Serine/arginine-rich splicing factor 6 protein 20101115 {GO:0008380=TAS, GO:0006369=TAS, GO:0010467=TAS, GO:0048025=IDA, GO:0006366=TAS, GO:0003723=IEA, GO:0006376=TAS, GO:0005730=IDA, GO:0031124=TAS, GO:0005634=IDA, GO:0006406=TAS, GO:0000166=IEA, GO:0000398=TAS, GO:0005654=TAS} RNA splicing, gene expression, mRNA 3'-end processing, mRNA export from nucleus, mRNA splice site selection, mRNA splicing, via spliceosome, negative regulation of mRNA splicing, via spliceosome, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter nucleolus, nucleoplasm, nucleus RNA binding, nucleotide binding NOT Human SRSF7 HPA UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:14559993, GO:0006397=PMID:8013463, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0048025=PMID:15009664, GO:0006366=Reactome:REACT_1366, GO:0003723=GO_REF:0000037, GO:0031124=Reactome:REACT_1849, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0006406=Reactome:REACT_1597, GO:0000166=GO_REF:0000002, GO:0000398=Reactome:REACT_1753, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_2241} Q16629 Serine/arginine-rich splicing factor 7 protein 20111111 {GO:0008380=TAS, GO:0005515=IPI, GO:0006397=TAS, GO:0010467=TAS, GO:0006369=TAS, GO:0048025=IDA, GO:0006366=TAS, GO:0003723=IEA, GO:0031124=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0006406=TAS, GO:0000166=IEA, GO:0000398=TAS, GO:0008270=IEA, GO:0005654=TAS} RNA splicing, gene expression, mRNA 3'-end processing, mRNA export from nucleus, mRNA processing, mRNA splicing, via spliceosome, negative regulation of mRNA splicing, via spliceosome, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter nucleolus, nucleoplasm, nucleus RNA binding, nucleic acid binding, nucleotide binding, protein binding, zinc ion binding NOT Human SRSF8 UniProtKB UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039} Q9BRL6 Serine/arginine-rich splicing factor 8 protein 20130413 {GO:0008380=IEA, GO:0006397=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0005634=IEA} RNA splicing, mRNA processing nucleus RNA binding, nucleotide binding Human UniProtKB-SubCell:SL-0191 SRSF9 HPA UniProtKB {GO:0006397=PMID:7556075, GO:0008380=Reactome:REACT_1735, GO:0006369=Reactome:REACT_894, GO:0010467=Reactome:REACT_71, GO:0048025=PMID:15009664, GO:0006366=Reactome:REACT_1366, GO:0003723=GO_REF:0000037, GO:0006376=PMID:7556075, GO:0005730=GO_REF:0000052, GO:0031124=Reactome:REACT_1849, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0006406=Reactome:REACT_1597, GO:0000166=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0005654=Reactome:REACT_1935} Q13242 Serine/arginine-rich splicing factor 9 protein 20120912 {GO:0006397=TAS, GO:0008380=TAS, GO:0006369=TAS, GO:0010467=TAS, GO:0048025=IDA, GO:0006366=TAS, GO:0003723=IEA, GO:0006376=TAS, GO:0005730=IDA, GO:0031124=TAS, GO:0005634=IDA, GO:0003676=IEA, GO:0006406=TAS, GO:0000166=IEA, GO:0000398=TAS, GO:0005654=TAS} RNA splicing, gene expression, mRNA 3'-end processing, mRNA export from nucleus, mRNA processing, mRNA splice site selection, mRNA splicing, via spliceosome, negative regulation of mRNA splicing, via spliceosome, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter nucleolus, nucleoplasm, nucleus RNA binding, nucleic acid binding, nucleotide binding NOT Human SRXN1 UniProtKB UniProtKB {GO:0016667=PMID:15448164, GO:0032542=GO_REF:0000003, GO:0006979=PMID:15448164, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000002, GO:0005829=PMID:15448164} Q9BYN0 Sulfiredoxin-1 protein 20050324 {GO:0016667=IDA, GO:0032542=IEA, GO:0006979=IDA, GO:0005524=IEA, GO:0003677=IEA, GO:0005829=IDA} response to oxidative stress cytosol ATP binding, DNA binding, oxidoreductase activity, acting on a sulfur group of donors, sulfiredoxin activity Human SRY HPA UniProtKB {GO:0005515=PMID:15527767, GO:0005516=GO_REF:0000037, GO:0003700=GO_REF:0000002, GO:0003705=PMID:21412441, GO:0005634=PMID:21412441, GO:0003677=PMID:1425584, GO:0006351=GO_REF:0000038, GO:0030154=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0016607=GO_REF:0000039, GO:0030238=PMID:1695712, GO:0007548=GO_REF:0000037, GO:0045893=PMID:21412441, GO:2000020=PMID:21412441, GO:0008134=PMID:16582099} Q05066 Sex-determining region Y protein protein 20080205 {GO:0005515=IPI, GO:0005516=IEA, GO:0003700=IEA, GO:0003705=IDA, GO:0005634=IDA, GO:0003677=IDA, GO:0006351=IEA, GO:0030154=IEA, GO:0043231=IDA, GO:0005737=IDA, GO:0016607=IEA, GO:0030238=NAS, GO:0007548=IEA, GO:0045893=IDA, GO:2000020=IDA, GO:0008134=IPI} cell differentiation, male sex determination, positive regulation of male gonad development, positive regulation of transcription, DNA-dependent, sex differentiation, transcription, DNA-dependent cytoplasm, intracellular membrane-bounded organelle, nuclear speck, nucleus DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, calmodulin binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human SS18 IntAct UniProtKB {GO:0005515=PMID:22439931, GO:0005881=GO_REF:0000019, GO:0000902=GO_REF:0000019, GO:0030374=PMID:15919756, GO:0048013=GO_REF:0000019, GO:0045944=PMID:15919756, GO:0042493=GO_REF:0000019, GO:0000226=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037, GO:0007243=GO_REF:0000019} Q15532 Protein SSXT protein 20130415 {GO:0005515=IPI, GO:0005881=IEA, GO:0000902=IEA, GO:0030374=IDA, GO:0048013=IEA, GO:0045944=IDA, GO:0042493=IEA, GO:0000226=IEA, GO:0005634=IEA, GO:0006351=IEA, GO:0007243=IEA} cell morphogenesis, ephrin receptor signaling pathway, intracellular protein kinase cascade, microtubule cytoskeleton organization, positive regulation of transcription from RNA polymerase II promoter, response to drug, transcription, DNA-dependent cytoplasmic microtubule, nucleus ligand-dependent nuclear receptor transcription coactivator activity, protein binding Human UniProtKB:P15336 SS18L1 UniProtKB UniProtKB {GO:0016604=GO_REF:0000019, GO:0000780=GO_REF:0000019, GO:0000777=GO_REF:0000039, GO:0050773=GO_REF:0000019, GO:0005634=GO_REF:0000024, GO:0045893=GO_REF:0000024, GO:0016358=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} O75177 Calcium-responsive transactivator protein 20091216 {GO:0016604=IEA, GO:0000780=IEA, GO:0000777=IEA, GO:0050773=IEA, GO:0005634=ISS, GO:0045893=ISS, GO:0016358=IEA, GO:0006351=IEA, GO:0016568=IEA} chromatin modification, dendrite development, positive regulation of transcription, DNA-dependent, regulation of dendrite development, transcription, DNA-dependent condensed chromosome kinetochore, condensed nuclear chromosome, centromeric region, nuclear body, nucleus Human UniProtKB:Q91XJ0 SS18L2 null null {} null null null null {} null null null SSB PINC UniProtKB {GO:0006396=GO_REF:0000002, GO:0000049=PMID:10983981, GO:0008334=PMID:9154801, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000019, GO:0030529=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003729=PMID:9154801, GO:0006400=PMID:10983981} P05455 Lupus La protein protein 20030904 {GO:0006396=IEA, GO:0000049=TAS, GO:0008334=TAS, GO:0000166=IEA, GO:0003723=IEA, GO:0030529=IEA, GO:0005634=IEA, GO:0003729=TAS, GO:0006400=TAS} RNA processing, histone mRNA metabolic process, tRNA modification nucleus, ribonucleoprotein complex RNA binding, mRNA binding, nucleotide binding, tRNA binding Human SSBP1 HPA UniProtKB {GO:0042645=PMID:18063578, GO:0005515=PMID:22190034, GO:0006260=GO_REF:0000037, GO:0005739=GO_REF:0000052, GO:0003697=GO_REF:0000002, GO:0070584=GO_REF:0000019, GO:0003682=PMID:18063578, GO:0051096=PMID:12975372} Q04837 Single-stranded DNA-binding protein, mitochondrial protein 20080205 {GO:0042645=IDA, GO:0005515=IPI, GO:0006260=IEA, GO:0005739=IDA, GO:0003697=IEA, GO:0070584=IEA, GO:0003682=IDA, GO:0051096=IDA} DNA replication, mitochondrion morphogenesis, positive regulation of helicase activity mitochondrial nucleoid, mitochondrion chromatin binding, protein binding, single-stranded DNA binding Human SSBP2 LIFEdb UniProtKB {GO:0005737=GO_REF:0000054, GO:0006355=PMID:12079286, GO:0003697=PMID:12079286, GO:0005634=GO_REF:0000029} P81877 Single-stranded DNA-binding protein 2 protein 20100607 {GO:0005737=IDA, GO:0006355=NAS, GO:0003697=NAS, GO:0005634=NAS} regulation of transcription, DNA-dependent cytoplasm, nucleus single-stranded DNA binding Human SSBP3 ENSEMBL UniProtKB {GO:2000744=GO_REF:0000019, GO:0021501=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0006461=GO_REF:0000019, GO:0021547=GO_REF:0000019, GO:0003697=GO_REF:0000002, GO:0060323=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0005634=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q9NW25 Single-stranded DNA-binding protein 3 protein 20130413 {GO:2000744=IEA, GO:0021501=IEA, GO:0043234=IEA, GO:0043066=IEA, GO:0008284=IEA, GO:0006461=IEA, GO:0021547=IEA, GO:0003697=IEA, GO:0060323=IEA, GO:0045944=IEA, GO:0005634=IEA, GO:0006351=IEA} head morphogenesis, midbrain-hindbrain boundary initiation, negative regulation of apoptotic process, positive regulation of anterior head development, positive regulation of cell proliferation, positive regulation of transcription from RNA polymerase II promoter, prechordal plate formation, protein complex assembly, transcription, DNA-dependent nucleus, protein complex single-stranded DNA binding Human Ensembl:ENSMUSP00000030367 SSBP4 UniProtKB UniProtKB {GO:0003697=GO_REF:0000002, GO:0005634=GO_REF:0000039} Q9BWG4 Single-stranded DNA-binding protein 4 protein 20130413 {GO:0003697=IEA, GO:0005634=IEA} nucleus single-stranded DNA binding Human UniProtKB-SubCell:SL-0191 SSFA2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005886=GO_REF:0000002, GO:0003779=GO_REF:0000037} P28290 Sperm-specific antigen 2 protein 20130413 {GO:0005737=IEA, GO:0005886=IEA, GO:0003779=IEA} cytoplasm, plasma membrane actin binding Human UniProtKB-SubCell:SL-0086 SSH1 IntAct UniProtKB {GO:0005515=PMID:17350576, GO:0030036=PMID:11832213, GO:0005886=PMID:14645219, GO:0032268=PMID:19000834, GO:0030496=GO_REF:0000039, GO:0003779=PMID:11832213, GO:0003677=GO_REF:0000002, GO:0032154=GO_REF:0000039, GO:0071318=PMID:19000834, GO:0030027=GO_REF:0000039, GO:0010591=GO_REF:0000033, GO:0000902=PMID:14645219, GO:0005737=PMID:14645219, GO:0006470=PMID:14645219, GO:0008064=GO_REF:0000033, GO:0004721=PMID:19000834, GO:0008138=GO_REF:0000033, GO:0005856=GO_REF:0000039, GO:0050770=GO_REF:0000033, GO:0004725=GO_REF:0000003} Q8WYL5 Protein phosphatase Slingshot homolog 1 protein 20130415 {GO:0005515=IPI, GO:0030036=IMP, GO:0005886=IDA, GO:0032268=IDA, GO:0030496=IEA, GO:0003779=IDA, GO:0003677=IEA, GO:0032154=IEA, GO:0071318=IDA, GO:0030027=IEA, GO:0010591=IBA, GO:0000902=IMP, GO:0005737=IDA, GO:0006470=IMP, GO:0008064=IBA, GO:0004721=IMP, GO:0008138=IBA, GO:0005856=IEA, GO:0050770=IBA, GO:0004725=IEA} actin cytoskeleton organization, cell morphogenesis, cellular response to ATP, protein dephosphorylation, regulation of actin polymerization or depolymerization, regulation of axonogenesis, regulation of cellular protein metabolic process, regulation of lamellipodium assembly cleavage furrow, cytoplasm, cytoskeleton, lamellipodium, midbody, plasma membrane DNA binding, actin binding, phosphoprotein phosphatase activity, protein binding, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human UniProtKB:Q9BR76 SSH2 UniProtKB UniProtKB {GO:0010591=GO_REF:0000033, GO:0005737=GO_REF:0000033, GO:0030036=PMID:11832213, GO:0006470=PMID:11832213, GO:0008064=GO_REF:0000033, GO:0004721=PMID:11832213, GO:0003779=PMID:11832213, GO:0008138=GO_REF:0000033, GO:0005856=GO_REF:0000039, GO:0050770=GO_REF:0000033, GO:0003677=GO_REF:0000002, GO:0004725=GO_REF:0000003} Q76I76 Protein phosphatase Slingshot homolog 2 protein 20060206 {GO:0010591=IBA, GO:0005737=IBA, GO:0030036=IMP, GO:0006470=IMP, GO:0008064=IBA, GO:0004721=IDA, GO:0003779=IDA, GO:0008138=IBA, GO:0005856=IEA, GO:0050770=IBA, GO:0003677=IEA, GO:0004725=IEA} actin cytoskeleton organization, protein dephosphorylation, regulation of actin polymerization or depolymerization, regulation of axonogenesis, regulation of lamellipodium assembly cytoplasm, cytoskeleton DNA binding, actin binding, phosphoprotein phosphatase activity, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human SSH3 RefGenome UniProtKB {GO:0010591=GO_REF:0000033, GO:0005737=GO_REF:0000033, GO:0006470=GO_REF:0000033, GO:0008064=GO_REF:0000033, GO:0003779=GO_REF:0000033, GO:0005634=GO_REF:0000039, GO:0008138=GO_REF:0000033, GO:0005856=GO_REF:0000039, GO:0050770=GO_REF:0000033, GO:0003677=GO_REF:0000002, GO:0004725=GO_REF:0000003} Q8TE77 Protein phosphatase Slingshot homolog 3 protein 20110117 {GO:0010591=IBA, GO:0005737=IBA, GO:0006470=IBA, GO:0008064=IBA, GO:0003779=IBA, GO:0005634=IEA, GO:0008138=IBA, GO:0005856=IEA, GO:0050770=IBA, GO:0003677=IEA, GO:0004725=IEA} protein dephosphorylation, regulation of actin polymerization or depolymerization, regulation of axonogenesis, regulation of lamellipodium assembly cytoplasm, cytoskeleton, nucleus DNA binding, actin binding, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human PANTHER:PTN000016922 SSNA1 Reactome UniProtKB {GO:0005813=PMID:21399614, GO:0042073=GO_REF:0000019, GO:0000086=Reactome:REACT_2203, GO:0060830=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0000278=Reactome:REACT_152, GO:0005829=Reactome:REACT_15470, GO:0042802=GO_REF:0000019} O43805 Sjoegren syndrome nuclear autoantigen 1 protein 20130213 {GO:0005813=IDA, GO:0042073=IEA, GO:0000086=TAS, GO:0060830=IEA, GO:0005634=IEA, GO:0000278=TAS, GO:0005829=TAS, GO:0042802=IEA} G2/M transition of mitotic cell cycle, ciliary receptor clustering involved in smoothened signaling pathway, intraflagellar transport, mitotic cell cycle centrosome, cytosol, nucleus identical protein binding Human SSPN LIFEdb UniProtKB {GO:0030133=GO_REF:0000054, GO:0042383=GO_REF:0000039, GO:0006936=PMID:9395445, GO:0030054=GO_REF:0000037, GO:0016010=PMID:9395445, GO:0005887=PMID:9395445, GO:0045211=GO_REF:0000039, GO:0016021=GO_REF:0000002, GO:0007155=PMID:9395445} Q14714 Sarcospan protein 20100607 {GO:0030133=IDA, GO:0042383=IEA, GO:0006936=TAS, GO:0030054=IEA, GO:0016010=TAS, GO:0005887=TAS, GO:0045211=IEA, GO:0016021=IEA, GO:0007155=TAS} cell adhesion, muscle contraction cell junction, dystrophin-associated glycoprotein complex, integral to membrane, integral to plasma membrane, postsynaptic membrane, sarcolemma, transport vesicle Human SSPO UniProtKB UniProtKB {GO:0007155=GO_REF:0000037, GO:0030414=GO_REF:0000002} A2VEC9 SCO-spondin protein 20130413 {GO:0007155=IEA, GO:0030414=IEA} cell adhesion peptidase inhibitor activity Human UniProtKB-KW:KW-0130 SSR1 HPA UniProtKB {GO:0010467=Reactome:REACT_71, GO:0008284=PMID:10437777, GO:0005783=GO_REF:0000052, GO:0006614=Reactome:REACT_115902, GO:0006613=PMID:8050590, GO:0005789=Reactome:REACT_115957, GO:0016021=GO_REF:0000037, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0030968=Reactome:REACT_18356} P43307 Translocon-associated protein subunit alpha protein 20080818 {GO:0010467=TAS, GO:0008284=TAS, GO:0005783=IDA, GO:0006614=TAS, GO:0006613=TAS, GO:0005789=TAS, GO:0016021=IEA, GO:0006987=TAS, GO:0044267=TAS, GO:0006412=TAS, GO:0030968=TAS} SRP-dependent cotranslational protein targeting to membrane, activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, cotranslational protein targeting to membrane, endoplasmic reticulum unfolded protein response, gene expression, positive regulation of cell proliferation, translation endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane Human SSR2 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0005783=PMID:7789174, GO:0006614=Reactome:REACT_115902, GO:0006613=PMID:7789174, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014} P43308 Translocon-associated protein subunit beta protein 20130213 {GO:0010467=TAS, GO:0005783=TAS, GO:0006614=TAS, GO:0006613=TAS, GO:0005789=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0006412=TAS} SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, cotranslational protein targeting to membrane, gene expression, translation endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane Human SSR3 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0005784=GO_REF:0000002, GO:0006614=Reactome:REACT_115902, GO:0006613=GO_REF:0000002, GO:0030176=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014} Q9UNL2 Translocon-associated protein subunit gamma protein 20130213 {GO:0010467=TAS, GO:0005784=IEA, GO:0006614=TAS, GO:0006613=IEA, GO:0030176=IEA, GO:0044267=TAS, GO:0006412=TAS} SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, cotranslational protein targeting to membrane, gene expression, translation Sec61 translocon complex, integral to endoplasmic reticulum membrane Human SSR4 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0005784=PMID:7492314, GO:0005783=GO_REF:0000002, GO:0006614=Reactome:REACT_115902, GO:0005509=GO_REF:0000029, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014, GO:0006886=GO_REF:0000029} P51571 Translocon-associated protein subunit delta protein 20130213 {GO:0010467=TAS, GO:0005784=NAS, GO:0005783=IEA, GO:0006614=TAS, GO:0005509=NAS, GO:0016021=IEA, GO:0044267=TAS, GO:0006412=TAS, GO:0006886=NAS} SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, gene expression, intracellular protein transport, translation Sec61 translocon complex, endoplasmic reticulum, integral to membrane calcium ion binding Human SSRP1 HPA UniProtKB {GO:0005515=PMID:19836239, GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000037, GO:0006368=Reactome:REACT_1845, GO:0006366=Reactome:REACT_1366, GO:0005694=GO_REF:0000039, GO:0005730=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0050434=Reactome:REACT_6162, GO:0006260=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0006281=GO_REF:0000037, GO:0003682=GO_REF:0000019, GO:0016032=Reactome:REACT_6256, GO:0005654=Reactome:REACT_6355} Q08945 FACT complex subunit SSRP1 protein 20080205 {GO:0005515=IPI, GO:0022415=TAS, GO:0010467=TAS, GO:0006355=IEA, GO:0006368=TAS, GO:0006366=TAS, GO:0005694=IEA, GO:0005730=IEA, GO:0005634=IDA, GO:0003677=IEA, GO:0050434=TAS, GO:0006260=IEA, GO:0005737=IDA, GO:0006281=IEA, GO:0003682=IEA, GO:0016032=TAS, GO:0005654=TAS} DNA repair, DNA replication, gene expression, positive regulation of viral transcription, regulation of transcription, DNA-dependent, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, viral reproduction, viral reproductive process chromosome, cytoplasm, nucleolus, nucleoplasm, nucleus DNA binding, chromatin binding, protein binding Human SSSCA1 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0007067=GO_REF:0000037, GO:0051301=GO_REF:0000037, GO:0042802=GO_REF:0000019} O60232 Sjoegren syndrome/scleroderma autoantigen 1 protein 20130415 {GO:0005515=IPI, GO:0007067=IEA, GO:0051301=IEA, GO:0042802=IEA} cell division, mitosis identical protein binding, protein binding Human UniProtKB:Q9Q2G4 SST Reactome UniProtKB {GO:0030334=GO_REF:0000019, GO:0008285=PMID:9886848, GO:0009408=GO_REF:0000019, GO:0007584=PMID:6145156, GO:0042493=GO_REF:0000019, GO:0007586=PMID:6145156, GO:0007267=PMID:6145156, GO:0007268=PMID:9437026, GO:0005576=Reactome:REACT_22289, GO:0006972=GO_REF:0000019, GO:0048545=GO_REF:0000019, GO:0005615=PMID:9437026, GO:0005179=PMID:9886848, GO:0007186=PMID:8405411, GO:0043025=GO_REF:0000019, GO:0043200=GO_REF:0000019, GO:0008628=PMID:8961277, GO:0007166=PMID:9437026} P61278 Somatostatin protein 20080730 {GO:0030334=IEA, GO:0008285=TAS, GO:0009408=IEA, GO:0007584=TAS, GO:0042493=IEA, GO:0007586=TAS, GO:0007267=TAS, GO:0007268=TAS, GO:0005576=TAS, GO:0006972=IEA, GO:0048545=IEA, GO:0005615=TAS, GO:0005179=TAS, GO:0007186=TAS, GO:0043025=IEA, GO:0043200=IEA, GO:0008628=TAS, GO:0007166=TAS} G-protein coupled receptor signaling pathway, cell surface receptor signaling pathway, cell-cell signaling, digestion, hormone-mediated apoptotic signaling pathway, hyperosmotic response, negative regulation of cell proliferation, regulation of cell migration, response to amino acid stimulus, response to drug, response to heat, response to nutrient, response to steroid hormone stimulus, synaptic transmission extracellular region, extracellular space, neuronal cell body hormone activity Human SSTR1 Reactome UniProtKB {GO:0008285=GO_REF:0000002, GO:0005886=Reactome:REACT_22289, GO:0007584=PMID:1346068, GO:0007586=PMID:1346068, GO:0007267=PMID:1346068, GO:0021549=GO_REF:0000019, GO:0007215=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0004994=PMID:1346068, GO:0005737=GO_REF:0000019, GO:0042594=GO_REF:0000019, GO:0005887=PMID:1346068, GO:0007187=PMID:8405411, GO:0071392=GO_REF:0000019, GO:0030900=GO_REF:0000019, GO:0007166=PMID:1346068} P30872 Somatostatin receptor type 1 protein 20080730 {GO:0008285=IEA, GO:0005886=TAS, GO:0007584=TAS, GO:0007586=TAS, GO:0007267=TAS, GO:0021549=IEA, GO:0007215=IEA, GO:0007283=IEA, GO:0004994=IDA, GO:0005737=IEA, GO:0042594=IEA, GO:0005887=TAS, GO:0007187=TAS, GO:0071392=IEA, GO:0030900=IEA, GO:0007166=TAS} G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, cell surface receptor signaling pathway, cell-cell signaling, cellular response to estradiol stimulus, cerebellum development, digestion, forebrain development, glutamate receptor signaling pathway, negative regulation of cell proliferation, response to nutrient, response to starvation, spermatogenesis cytoplasm, integral to plasma membrane, plasma membrane somatostatin receptor activity Human SSTR2 Reactome UniProtKB {GO:0005515=PMID:10551867, GO:0008285=PMID:9892014, GO:0005886=Reactome:REACT_22289, GO:0007584=PMID:1346068, GO:0007586=PMID:1346068, GO:0007267=PMID:1346068, GO:0021549=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0030165=PMID:10551867, GO:0007193=GO_REF:0000019, GO:0030432=GO_REF:0000019, GO:0071385=GO_REF:0000019, GO:0004994=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0006937=GO_REF:0000019, GO:0042594=GO_REF:0000019, GO:0007187=PMID:7914078, GO:0005887=PMID:7914078, GO:0071392=GO_REF:0000019, GO:0030900=GO_REF:0000019} P30874 Somatostatin receptor type 2 protein 20080730 {GO:0005515=IPI, GO:0008285=TAS, GO:0005886=TAS, GO:0007584=TAS, GO:0007586=TAS, GO:0007267=TAS, GO:0021549=IEA, GO:0007283=IEA, GO:0030165=IPI, GO:0007193=IEA, GO:0030432=IEA, GO:0071385=IEA, GO:0004994=IEA, GO:0005737=IEA, GO:0006937=IEA, GO:0042594=IEA, GO:0007187=TAS, GO:0005887=TAS, GO:0071392=IEA, GO:0030900=IEA} G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, cell-cell signaling, cellular response to estradiol stimulus, cellular response to glucocorticoid stimulus, cerebellum development, digestion, forebrain development, negative regulation of cell proliferation, peristalsis, regulation of muscle contraction, response to nutrient, response to starvation, spermatogenesis cytoplasm, integral to plasma membrane, plasma membrane PDZ domain binding, protein binding, somatostatin receptor activity Human SSTR3 GOC UniProtKB {GO:0008285=PMID:8961277, GO:0005886=Reactome:REACT_22289, GO:0038170=PMID:8405411, GO:0007267=PMID:1337145, GO:0031513=GO_REF:0000024, GO:0021549=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0071385=GO_REF:0000019, GO:0004994=GO_REF:0000002, GO:0005737=GO_REF:0000019, GO:0042594=GO_REF:0000019, GO:0005887=PMID:1337145, GO:0007187=PMID:8405411, GO:0071392=GO_REF:0000019, GO:0030900=GO_REF:0000019, GO:0008628=PMID:8961277} P32745 Somatostatin receptor type 3 protein 20130413 {GO:0008285=TAS, GO:0005886=TAS, GO:0038170=TAS, GO:0007267=TAS, GO:0031513=ISS, GO:0021549=IEA, GO:0007283=IEA, GO:0071385=IEA, GO:0004994=IEA, GO:0005737=IEA, GO:0042594=IEA, GO:0005887=TAS, GO:0007187=TAS, GO:0071392=IEA, GO:0030900=IEA, GO:0008628=TAS} G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, cell-cell signaling, cellular response to estradiol stimulus, cellular response to glucocorticoid stimulus, cerebellum development, forebrain development, hormone-mediated apoptotic signaling pathway, negative regulation of cell proliferation, response to starvation, somatostatin signaling pathway, spermatogenesis cytoplasm, integral to plasma membrane, nonmotile primary cilium, plasma membrane somatostatin receptor activity Human SSTR4 Reactome UniProtKB {GO:0019369=GO_REF:0000019, GO:0008285=PMID:9892014, GO:0005886=Reactome:REACT_22289, GO:0071385=GO_REF:0000019, GO:0004994=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0016477=GO_REF:0000019, GO:0007186=PMID:9892014, GO:0005887=PMID:8100352, GO:0007187=PMID:8405411, GO:0030815=GO_REF:0000019, GO:0030900=GO_REF:0000019, GO:0043410=GO_REF:0000019} P31391 Somatostatin receptor type 4 protein 20080730 {GO:0019369=IEA, GO:0008285=TAS, GO:0005886=TAS, GO:0071385=IEA, GO:0004994=IEA, GO:0005737=IEA, GO:0016477=IEA, GO:0007186=TAS, GO:0005887=TAS, GO:0007187=TAS, GO:0030815=IEA, GO:0030900=IEA, GO:0043410=IEA} G-protein coupled receptor signaling pathway, G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, arachidonic acid metabolic process, cell migration, cellular response to glucocorticoid stimulus, forebrain development, negative regulation of cAMP metabolic process, negative regulation of cell proliferation, positive regulation of MAPK cascade cytoplasm, integral to plasma membrane, plasma membrane somatostatin receptor activity Human SSTR5 GOC UniProtKB {GO:0004994=GO_REF:0000002, GO:0008285=PMID:9892014, GO:0005886=Reactome:REACT_22289, GO:0007186=PMID:9892014, GO:0050796=GO_REF:0000019, GO:0007187=PMID:7908405, GO:0005887=PMID:7908405, GO:0038170=PMID:9892014, GO:0042593=GO_REF:0000019, GO:0016021=GO_REF:0000038} P35346 Somatostatin receptor type 5 protein 20130413 {GO:0004994=IEA, GO:0008285=TAS, GO:0005886=TAS, GO:0007186=TAS, GO:0050796=IEA, GO:0007187=TAS, GO:0005887=TAS, GO:0038170=TAS, GO:0042593=IEA, GO:0016021=IEA} G-protein coupled receptor signaling pathway, G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, glucose homeostasis, negative regulation of cell proliferation, regulation of insulin secretion, somatostatin signaling pathway integral to membrane, integral to plasma membrane, plasma membrane somatostatin receptor activity Human SSU72 UniProtKB UniProtKB {GO:0006378=PMID:20861839, GO:0005737=GO_REF:0000039, GO:0070940=PMID:20861839, GO:0005634=GO_REF:0000039, GO:0008420=PMID:20861839} Q9NP77 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 protein 20121218 {GO:0006378=IMP, GO:0005737=IEA, GO:0070940=IDA, GO:0005634=IEA, GO:0008420=IDA} dephosphorylation of RNA polymerase II C-terminal domain, mRNA polyadenylation cytoplasm, nucleus CTD phosphatase activity Human SSX1 PINC UniProtKB {GO:0006355=GO_REF:0000037, GO:0003714=PMID:10072425, GO:0005634=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q16384 Protein SSX1 protein 20030904 {GO:0006355=IEA, GO:0003714=TAS, GO:0005634=IEA, GO:0003676=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus nucleic acid binding, transcription corepressor activity Human SSX2 LIFEdb UniProtKB {GO:0005515=PMID:12007189, GO:0006355=PMID:7539744, GO:0005634=GO_REF:0000054, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q16385 Protein SSX2 protein 20100607 {GO:0005515=IPI, GO:0006355=NAS, GO:0005634=IDA, GO:0003676=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus nucleic acid binding, protein binding Human SSX2IP LIFEdb UniProtKB {GO:0043234=GO_REF:0000054, GO:0005913=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0007155=GO_REF:0000037} Q9Y2D8 Afadin- and alpha-actinin-binding protein protein 20100607 {GO:0043234=IDA, GO:0005913=IEA, GO:0019904=IEA, GO:0005634=IEA, GO:0007155=IEA} cell adhesion cell-cell adherens junction, nucleus, protein complex protein domain specific binding Human SSX3 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q99909 Protein SSX3 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0003676=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus nucleic acid binding Human UniProtKB-KW:KW-0805 SSX4 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} O60224 Protein SSX4 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0003676=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus nucleic acid binding Human UniProtKB-KW:KW-0805 SSX5 InterPro UniProtKB {GO:0006355=GO_REF:0000002, GO:0005634=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q5JQ63 Synovial sarcoma, X breakpoint 5 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0003676=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus nucleic acid binding Human InterPro:IPR019041 ST13 IntAct UniProtKB {GO:0005515=PMID:21163940, GO:0032564=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0051087=GO_REF:0000019, GO:0061084=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0042802=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0005737=PMID:8721986, GO:0070389=GO_REF:0000019, GO:0006457=PMID:8721986, GO:0030544=GO_REF:0000019, GO:0051260=GO_REF:0000019, GO:0051082=GO_REF:0000019, GO:0030674=PMID:8721986} P50502 Hsc70-interacting protein protein 20130415 {GO:0005515=IPI, GO:0032564=IEA, GO:0019904=IEA, GO:0051087=IEA, GO:0061084=IEA, GO:0032403=IEA, GO:0005829=IEA, GO:0042802=IEA, GO:0043234=IEA, GO:0005737=TAS, GO:0070389=IEA, GO:0006457=TAS, GO:0030544=IEA, GO:0051260=IEA, GO:0051082=IEA, GO:0030674=TAS} chaperone cofactor-dependent protein refolding, negative regulation of protein refolding, protein folding, protein homooligomerization cytoplasm, cytosol, protein complex Hsp70 protein binding, chaperone binding, dATP binding, identical protein binding, protein binding, protein binding, bridging, protein complex binding, protein domain specific binding, unfolded protein binding Human UniProtKB:P49768 ST14 PINC UniProtKB {GO:0005886=PMID:10831593, GO:0004252=GO_REF:0000002, GO:0005887=PMID:10831593, GO:0006508=GO_REF:0000002, GO:0005576=GO_REF:0000019, GO:0019897=GO_REF:0000019} Q9Y5Y6 Suppressor of tumorigenicity 14 protein protein 20030904 {GO:0005886=TAS, GO:0004252=IEA, GO:0005887=TAS, GO:0006508=IEA, GO:0005576=IEA, GO:0019897=IEA} proteolysis extracellular region, extrinsic to plasma membrane, integral to plasma membrane, plasma membrane serine-type endopeptidase activity Human ST18 UniProtKB UniProtKB {GO:0003700=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O60284 Suppression of tumorigenicity 18 protein protein 20130413 {GO:0003700=IEA, GO:0008270=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB-SubCell:SL-0191 ST3GAL1 Reactome UniProtKB {GO:0005794=GO_REF:0000038, GO:0005975=Reactome:REACT_474, GO:0016266=Reactome:REACT_115835, GO:0005576=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0003836=GO_REF:0000003, GO:0042339=Reactome:REACT_121288, GO:0030173=GO_REF:0000002, GO:0000139=Reactome:REACT_121285, GO:0018146=Reactome:REACT_121120, GO:0032580=GO_REF:0000039, GO:0006468=GO_REF:0000019, GO:0006486=GO_REF:0000002, GO:0016021=GO_REF:0000038, GO:0044267=Reactome:REACT_17015, GO:0030203=Reactome:REACT_121315, GO:0006464=PMID:10504389, GO:0043687=Reactome:REACT_22161} Q11201 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 protein 20130301 {GO:0005794=IEA, GO:0005975=TAS, GO:0016266=TAS, GO:0005576=IEA, GO:0044281=TAS, GO:0003836=IEA, GO:0042339=TAS, GO:0030173=IEA, GO:0000139=TAS, GO:0018146=TAS, GO:0032580=IEA, GO:0006468=IEA, GO:0006486=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0030203=TAS, GO:0006464=TAS, GO:0043687=TAS} O-glycan processing, carbohydrate metabolic process, cellular protein metabolic process, cellular protein modification process, glycosaminoglycan metabolic process, keratan sulfate biosynthetic process, keratan sulfate metabolic process, post-translational protein modification, protein glycosylation, protein phosphorylation, small molecule metabolic process Golgi apparatus, Golgi cisterna membrane, Golgi membrane, extracellular region, integral to Golgi membrane, integral to membrane beta-galactoside (CMP) alpha-2,3-sialyltransferase activity Human ST3GAL2 HPA UniProtKB {GO:0005794=GO_REF:0000052, GO:0006040=PMID:9266697, GO:0005975=Reactome:REACT_474, GO:0016266=Reactome:REACT_115835, GO:0005576=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0003836=GO_REF:0000003, GO:0042339=Reactome:REACT_121288, GO:0005737=GO_REF:0000052, GO:0030173=GO_REF:0000002, GO:0000139=Reactome:REACT_121285, GO:0018146=Reactome:REACT_121120, GO:0032580=GO_REF:0000039, GO:0044267=Reactome:REACT_17015, GO:0030203=Reactome:REACT_121315, GO:0006464=PMID:9266697, GO:0043687=Reactome:REACT_22161} Q16842 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 protein 20090616 {GO:0005794=IDA, GO:0006040=TAS, GO:0005975=TAS, GO:0016266=TAS, GO:0005576=IEA, GO:0044281=TAS, GO:0003836=IEA, GO:0042339=TAS, GO:0005737=IDA, GO:0030173=IEA, GO:0000139=TAS, GO:0018146=TAS, GO:0032580=IEA, GO:0044267=TAS, GO:0030203=TAS, GO:0006464=TAS, GO:0043687=TAS} O-glycan processing, amino sugar metabolic process, carbohydrate metabolic process, cellular protein metabolic process, cellular protein modification process, glycosaminoglycan metabolic process, keratan sulfate biosynthetic process, keratan sulfate metabolic process, post-translational protein modification, small molecule metabolic process Golgi apparatus, Golgi cisterna membrane, Golgi membrane, cytoplasm, extracellular region, integral to Golgi membrane beta-galactoside (CMP) alpha-2,3-sialyltransferase activity Human ST3GAL3 Reactome UniProtKB {GO:0008373=GO_REF:0000002, GO:0005794=GO_REF:0000038, GO:0005975=Reactome:REACT_474, GO:0016266=Reactome:REACT_115835, GO:0005576=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0003836=GO_REF:0000019, GO:0042339=Reactome:REACT_121288, GO:0030173=GO_REF:0000002, GO:0008118=GO_REF:0000003, GO:0000139=Reactome:REACT_121285, GO:0018146=Reactome:REACT_121120, GO:0032580=GO_REF:0000039, GO:0006486=GO_REF:0000002, GO:0016021=GO_REF:0000038, GO:0044267=Reactome:REACT_17015, GO:0030203=Reactome:REACT_121315, GO:0043687=Reactome:REACT_22161} Q11203 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase protein 20130301 {GO:0008373=IEA, GO:0005794=IEA, GO:0005975=TAS, GO:0016266=TAS, GO:0005576=IEA, GO:0044281=TAS, GO:0003836=IEA, GO:0042339=TAS, GO:0030173=IEA, GO:0008118=IEA, GO:0000139=TAS, GO:0018146=TAS, GO:0032580=IEA, GO:0006486=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0030203=TAS, GO:0043687=TAS} O-glycan processing, carbohydrate metabolic process, cellular protein metabolic process, glycosaminoglycan metabolic process, keratan sulfate biosynthetic process, keratan sulfate metabolic process, post-translational protein modification, protein glycosylation, small molecule metabolic process Golgi apparatus, Golgi cisterna membrane, Golgi membrane, extracellular region, integral to Golgi membrane, integral to membrane N-acetyllactosaminide alpha-2,3-sialyltransferase activity, beta-galactoside (CMP) alpha-2,3-sialyltransferase activity, sialyltransferase activity Human ST3GAL4 UniProtKB UniProtKB {GO:0008373=GO_REF:0000002, GO:0005794=GO_REF:0000038, GO:0005975=Reactome:REACT_474, GO:0016266=Reactome:REACT_115835, GO:0047288=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0003836=GO_REF:0000003, GO:0042339=Reactome:REACT_121288, GO:0030173=GO_REF:0000002, GO:0000139=Reactome:REACT_121285, GO:0018146=Reactome:REACT_121120, GO:0032580=GO_REF:0000039, GO:0006486=GO_REF:0000002, GO:0016021=GO_REF:0000038, GO:0044267=Reactome:REACT_17015, GO:0030203=Reactome:REACT_121315, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q8N6A6 Alpha 2,3-sialyltransferase IV type A1-12 protein 20130413 {GO:0008373=IEA, GO:0005794=IEA, GO:0005975=TAS, GO:0016266=TAS, GO:0047288=IEA, GO:0005576=IEA, GO:0044281=TAS, GO:0003836=IEA, GO:0042339=TAS, GO:0030173=IEA, GO:0000139=TAS, GO:0018146=TAS, GO:0032580=IEA, GO:0006486=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0030203=TAS, GO:0043687=TAS, GO:0018279=TAS} O-glycan processing, carbohydrate metabolic process, cellular protein metabolic process, glycosaminoglycan metabolic process, keratan sulfate biosynthetic process, keratan sulfate metabolic process, post-translational protein modification, protein N-linked glycosylation via asparagine, protein glycosylation, small molecule metabolic process Golgi apparatus, Golgi cisterna membrane, Golgi membrane, extracellular region, integral to Golgi membrane, integral to membrane beta-galactoside (CMP) alpha-2,3-sialyltransferase activity, monosialoganglioside sialyltransferase activity, sialyltransferase activity Human EC:2.4.99.4 ST3GAL6 Reactome UniProtKB {GO:0006664=PMID:10206952, GO:0008373=GO_REF:0000002, GO:0005794=GO_REF:0000038, GO:0009311=PMID:10206952, GO:0005975=Reactome:REACT_474, GO:0044281=Reactome:REACT_111217, GO:0042339=Reactome:REACT_121288, GO:0030173=GO_REF:0000002, GO:0052798=PMID:10206952, GO:0000139=Reactome:REACT_121285, GO:0018146=Reactome:REACT_121120, GO:0071354=PMID:17944600, GO:0006486=GO_REF:0000002, GO:0016021=PMID:10206952, GO:0030203=Reactome:REACT_121315, GO:0006464=PMID:10206952} Q9Y274 Type 2 lactosamine alpha-2,3-sialyltransferase protein 20130301 {GO:0006664=IDA, GO:0008373=IEA, GO:0005794=IEA, GO:0009311=IDA, GO:0005975=TAS, GO:0044281=TAS, GO:0042339=TAS, GO:0030173=IEA, GO:0052798=IDA, GO:0000139=TAS, GO:0018146=TAS, GO:0071354=IEP, GO:0006486=IEA, GO:0016021=NAS, GO:0030203=TAS, GO:0006464=IDA} carbohydrate metabolic process, cellular protein modification process, cellular response to interleukin-6, glycolipid metabolic process, glycosaminoglycan metabolic process, keratan sulfate biosynthetic process, keratan sulfate metabolic process, oligosaccharide metabolic process, protein glycosylation, small molecule metabolic process Golgi apparatus, Golgi membrane, integral to Golgi membrane, integral to membrane beta-galactoside alpha-2,3-sialyltransferase activity, sialyltransferase activity Human ST5 UniProtKB UniProtKB {GO:0017112=PMID:20937701} P78524 Suppression of tumorigenicity 5 protein protein 20121004 {GO:0017112=IDA} Rab guanyl-nucleotide exchange factor activity Human ST6GAL1 Reactome UniProtKB {GO:0008373=PMID:21081508, GO:0005794=GO_REF:0000038, GO:0016266=Reactome:REACT_115835, GO:0005576=GO_REF:0000039, GO:0003835=GO_REF:0000003, GO:0030173=GO_REF:0000002, GO:0000139=Reactome:REACT_115991, GO:0032580=GO_REF:0000039, GO:0006959=PMID:7786324, GO:0006486=GO_REF:0000002, GO:0016021=GO_REF:0000038, GO:0044267=Reactome:REACT_17015, GO:0006464=PMID:2408023, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} P15907 Beta-galactoside alpha-2,6-sialyltransferase 1 protein 20130301 {GO:0008373=IDA, GO:0005794=IEA, GO:0016266=TAS, GO:0005576=IEA, GO:0003835=IEA, GO:0030173=IEA, GO:0000139=TAS, GO:0032580=IEA, GO:0006959=TAS, GO:0006486=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0006464=NAS, GO:0043687=TAS, GO:0018279=TAS} O-glycan processing, cellular protein metabolic process, cellular protein modification process, humoral immune response, post-translational protein modification, protein N-linked glycosylation via asparagine, protein glycosylation Golgi apparatus, Golgi cisterna membrane, Golgi membrane, extracellular region, integral to Golgi membrane, integral to membrane beta-galactoside alpha-2,6-sialyltransferase activity, sialyltransferase activity Human ST6GAL2 UniProtKB UniProtKB {GO:0008373=GO_REF:0000002, GO:0009311=PMID:12235148, GO:0005794=GO_REF:0000038, GO:0032580=GO_REF:0000039, GO:0007275=PMID:12235148, GO:0006486=GO_REF:0000002, GO:0016021=PMID:12235148, GO:0040007=PMID:12235148, GO:0003835=PMID:12235148} Q96JF0 Beta-galactoside alpha-2,6-sialyltransferase 2 protein 20031216 {GO:0008373=IEA, GO:0009311=IDA, GO:0005794=IEA, GO:0032580=IEA, GO:0007275=NAS, GO:0006486=IEA, GO:0016021=NAS, GO:0040007=NAS, GO:0003835=IDA} growth, multicellular organismal development, oligosaccharide metabolic process, protein glycosylation Golgi apparatus, Golgi cisterna membrane, integral to membrane beta-galactoside alpha-2,6-sialyltransferase activity, sialyltransferase activity Human ST6GALNAC1 UniPathway UniProtKB {GO:0001665=GO_REF:0000003, GO:0009312=GO_REF:0000019, GO:0008373=PMID:10536037, GO:0005794=GO_REF:0000038, GO:0000139=GO_REF:0000039, GO:0006486=GO_REF:0000041, GO:0016021=GO_REF:0000037} Q9NSC7 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 protein 20130413 {GO:0001665=IEA, GO:0009312=IEA, GO:0008373=NAS, GO:0005794=IEA, GO:0000139=IEA, GO:0006486=IEA, GO:0016021=IEA} oligosaccharide biosynthetic process, protein glycosylation Golgi apparatus, Golgi membrane, integral to membrane alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity, sialyltransferase activity Human UniPathway:UPA00378 ST6GALNAC2 Reactome UniProtKB {GO:0030173=GO_REF:0000002, GO:0008373=GO_REF:0000002, GO:0005794=GO_REF:0000038, GO:0000139=Reactome:REACT_115996, GO:0016266=Reactome:REACT_115835, GO:0006486=GO_REF:0000002, GO:0016021=GO_REF:0000038, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q9UJ37 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 protein 20130301 {GO:0030173=IEA, GO:0008373=IEA, GO:0005794=IEA, GO:0000139=TAS, GO:0016266=TAS, GO:0006486=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0043687=TAS} O-glycan processing, cellular protein metabolic process, post-translational protein modification, protein glycosylation Golgi apparatus, Golgi membrane, integral to Golgi membrane, integral to membrane sialyltransferase activity Human ST6GALNAC4 HPA UniProtKB {GO:0006664=PMID:10207017, GO:0008373=PMID:10207017, GO:0005794=GO_REF:0000052, GO:0000139=Reactome:REACT_115974, GO:0047290=GO_REF:0000003, GO:0016266=Reactome:REACT_115835, GO:0005634=GO_REF:0000052, GO:0006486=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q9H4F1 Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase protein 20101115 {GO:0006664=TAS, GO:0008373=TAS, GO:0005794=IDA, GO:0000139=TAS, GO:0047290=IEA, GO:0016266=TAS, GO:0005634=IDA, GO:0006486=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0043687=TAS} O-glycan processing, cellular protein metabolic process, glycolipid metabolic process, post-translational protein modification, protein glycosylation Golgi apparatus, Golgi membrane, integral to membrane, nucleus (alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity, sialyltransferase activity Human ST6GALNAC6 BHF-UCL UniProtKB {GO:0001665=GO_REF:0000024, GO:0006677=PMID:17123352, GO:0008373=PMID:17123352, GO:0009312=PMID:12668675, GO:0005794=GO_REF:0000038, GO:0005886=PMID:10702226, GO:0006687=PMID:17123352, GO:0009988=PMID:12668675, GO:0005737=GO_REF:0000024, GO:0009100=PMID:17123352, GO:0000139=GO_REF:0000039, GO:0001574=GO_REF:0000024, GO:0006486=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q969X2 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 protein 20110721 {GO:0001665=ISS, GO:0006677=IDA, GO:0008373=IDA, GO:0009312=ISS, GO:0005794=IEA, GO:0005886=NAS, GO:0006687=IDA, GO:0009988=IC, GO:0005737=ISS, GO:0009100=IDA, GO:0000139=IEA, GO:0001574=ISS, GO:0006486=IEA, GO:0016021=IEA} cell-cell recognition, ganglioside biosynthetic process, glycoprotein metabolic process, glycosphingolipid metabolic process, glycosylceramide metabolic process, oligosaccharide biosynthetic process, protein glycosylation Golgi apparatus, Golgi membrane, cytoplasm, integral to membrane, plasma membrane alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity, sialyltransferase activity Human ST7 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9NRC1 Suppressor of tumorigenicity 7 protein protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 ST7L BHF-UCL UniProtKB {GO:0030308=GO_REF:0000024, GO:0016021=GO_REF:0000037} Q8TDW4 Suppressor of tumorigenicity 7 protein-like protein 20110401 {GO:0030308=ISS, GO:0016021=IEA} negative regulation of cell growth integral to membrane Human UniProtKB:Q8K4P7 ST8SIA2 BHF-UCL UniProtKB {GO:0003828=PMID:10766765, GO:0008373=GO_REF:0000002, GO:0009311=PMID:10766765, GO:0005975=PMID:7559389, GO:0007399=PMID:9054414, GO:0030173=GO_REF:0000002, GO:0000139=Reactome:REACT_25115, GO:0007411=Reactome:REACT_18266, GO:0006491=PMID:10766765, GO:0001574=PMID:10766765, GO:0006486=PMID:10766765, GO:0033691=PMID:10766765, GO:0044267=Reactome:REACT_17015, GO:0006464=PMID:7559389, GO:0018279=Reactome:REACT_22426, GO:0043687=Reactome:REACT_22161} Q92186 Alpha-2,8-sialyltransferase 8B protein 20110720 {GO:0003828=IDA, GO:0008373=IEA, GO:0009311=IDA, GO:0005975=TAS, GO:0007399=TAS, GO:0030173=IEA, GO:0000139=TAS, GO:0007411=TAS, GO:0006491=IDA, GO:0001574=IDA, GO:0006486=IDA, GO:0033691=IC, GO:0044267=TAS, GO:0006464=TAS, GO:0018279=TAS, GO:0043687=TAS} N-glycan processing, axon guidance, carbohydrate metabolic process, cellular protein metabolic process, cellular protein modification process, ganglioside biosynthetic process, nervous system development, oligosaccharide metabolic process, post-translational protein modification, protein N-linked glycosylation via asparagine, protein glycosylation Golgi membrane, integral to Golgi membrane alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity, sialic acid binding, sialyltransferase activity Human GO:0003828 ST8SIA3 BHF-UCL UniProtKB {GO:0003828=PMID:9826427, GO:0008373=GO_REF:0000002, GO:0009311=PMID:10766765, GO:0005794=GO_REF:0000038, GO:0006688=PMID:9073076, GO:0030173=GO_REF:0000002, GO:0009100=PMID:9826427, GO:0000139=Reactome:REACT_25115, GO:0006491=PMID:10766765, GO:0001574=PMID:10766765, GO:0006486=PMID:10766765, GO:0033691=PMID:9826427, GO:0016021=GO_REF:0000038, GO:0044267=Reactome:REACT_17015, GO:0018279=Reactome:REACT_22426, GO:0043687=Reactome:REACT_22161} O43173 Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase protein 20110720 {GO:0003828=IDA, GO:0008373=IEA, GO:0009311=IDA, GO:0005794=IEA, GO:0006688=TAS, GO:0030173=IEA, GO:0009100=IDA, GO:0000139=TAS, GO:0006491=IDA, GO:0001574=IDA, GO:0006486=IDA, GO:0033691=IC, GO:0016021=IEA, GO:0044267=TAS, GO:0018279=TAS, GO:0043687=TAS} N-glycan processing, cellular protein metabolic process, ganglioside biosynthetic process, glycoprotein metabolic process, glycosphingolipid biosynthetic process, oligosaccharide metabolic process, post-translational protein modification, protein N-linked glycosylation via asparagine, protein glycosylation Golgi apparatus, Golgi membrane, integral to Golgi membrane, integral to membrane alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity, sialic acid binding, sialyltransferase activity Human GO:0003828 ST8SIA4 BHF-UCL UniProtKB {GO:0003828=PMID:10766765, GO:0030173=GO_REF:0000002, GO:0009311=PMID:10766765, GO:0000139=Reactome:REACT_18324, GO:0007411=Reactome:REACT_18266, GO:0006491=PMID:10766765, GO:0001574=PMID:10766765, GO:0006486=PMID:10766765, GO:0033691=PMID:10766765, GO:0006464=PMID:7854457, GO:0007399=PMID:9054414} Q92187 CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase protein 20110720 {GO:0003828=IDA, GO:0030173=IEA, GO:0009311=IDA, GO:0000139=TAS, GO:0007411=TAS, GO:0006491=IDA, GO:0001574=IDA, GO:0006486=IDA, GO:0033691=IC, GO:0006464=TAS, GO:0007399=TAS} N-glycan processing, axon guidance, cellular protein modification process, ganglioside biosynthetic process, nervous system development, oligosaccharide metabolic process, protein glycosylation Golgi membrane, integral to Golgi membrane alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity, sialic acid binding Human GO:0003828 ST8SIA6 BHF-UCL UniProtKB {GO:0009247=PMID:11980897, GO:0008373=PMID:11980897, GO:0005794=GO_REF:0000038, GO:0009311=PMID:11980897, GO:0016051=PMID:11980897, GO:0030173=GO_REF:0000002, GO:0009100=PMID:11980897, GO:0000139=Reactome:REACT_25115, GO:0006493=PMID:11980897, GO:0001574=PMID:11980897, GO:0006486=GO_REF:0000002, GO:0016021=GO_REF:0000038, GO:0044267=Reactome:REACT_17015, GO:0018279=Reactome:REACT_22426, GO:0043687=Reactome:REACT_22161} P61647 Alpha-2,8-sialyltransferase 8F protein 20110720 {GO:0009247=ISS, GO:0008373=ISS, GO:0005794=IEA, GO:0009311=ISS, GO:0016051=ISS, GO:0030173=IEA, GO:0009100=ISS, GO:0000139=TAS, GO:0006493=ISS, GO:0001574=ISS, GO:0006486=IEA, GO:0016021=IEA, GO:0044267=TAS, GO:0018279=TAS, GO:0043687=TAS} carbohydrate biosynthetic process, cellular protein metabolic process, ganglioside biosynthetic process, glycolipid biosynthetic process, glycoprotein metabolic process, oligosaccharide metabolic process, post-translational protein modification, protein N-linked glycosylation via asparagine, protein O-linked glycosylation, protein glycosylation Golgi apparatus, Golgi membrane, integral to Golgi membrane, integral to membrane sialyltransferase activity Human UniProtKB:Q8K4T1 STAB1 UniProtKB UniProtKB {GO:0007267=PMID:12077138, GO:0030169=PMID:12077138, GO:0015035=PMID:12077138, GO:0006898=PMID:12077138, GO:0005041=PMID:12077138, GO:0051635=PMID:12077138, GO:0006954=GO_REF:0000037, GO:0005540=GO_REF:0000002, GO:0005887=PMID:12077138, GO:0016525=PMID:12077138, GO:0007155=PMID:12077138, GO:0042742=PMID:12077138, GO:0005044=PMID:12077138} Q9NY15 Stabilin-1 protein 20040817 {GO:0007267=IDA, GO:0030169=IDA, GO:0015035=NAS, GO:0006898=TAS, GO:0005041=IDA, GO:0051635=IDA, GO:0006954=IEA, GO:0005540=IEA, GO:0005887=IDA, GO:0016525=IMP, GO:0007155=NAS, GO:0042742=IDA, GO:0005044=IDA} cell adhesion, cell-cell signaling, defense response to bacterium, inflammatory response, negative regulation of angiogenesis, receptor-mediated endocytosis integral to plasma membrane bacterial cell surface binding, hyaluronic acid binding, low-density lipoprotein particle binding, low-density lipoprotein receptor activity, protein disulfide oxidoreductase activity, scavenger receptor activity Human STAB2 HPA UniProtKB {GO:0005886=Reactome:REACT_120971, GO:0005975=Reactome:REACT_474, GO:0015035=PMID:12077138, GO:0030169=PMID:12077138, GO:0044281=Reactome:REACT_111217, GO:0001525=PMID:12077138, GO:0006898=PMID:12077138, GO:0006897=GO_REF:0000024, GO:0051636=PMID:11829752, GO:0005041=PMID:12077138, GO:0051635=PMID:12077138, GO:0005737=GO_REF:0000052, GO:0005540=GO_REF:0000024, GO:0005887=PMID:12077138, GO:0030212=Reactome:REACT_121083, GO:0030214=Reactome:REACT_120996, GO:0007155=PMID:12077138, GO:0030203=Reactome:REACT_121315, GO:0009897=GO_REF:0000024, GO:0042742=PMID:12077138, GO:0005044=PMID:12077138} Q8WWQ8 Stabilin-2 protein 20100326 {GO:0005886=TAS, GO:0005975=TAS, GO:0015035=NAS, GO:0030169=IDA, GO:0044281=TAS, GO:0001525=NAS, GO:0006898=TAS, GO:0006897=ISS, GO:0051636=IDA, GO:0005041=IDA, GO:0051635=IDA, GO:0005737=IDA, GO:0005540=ISS, GO:0005887=IDA, GO:0030212=TAS, GO:0030214=TAS, GO:0007155=NAS, GO:0030203=TAS, GO:0009897=ISS, GO:0042742=IDA, GO:0005044=IDA} angiogenesis, carbohydrate metabolic process, cell adhesion, defense response to bacterium, endocytosis, glycosaminoglycan metabolic process, hyaluronan catabolic process, hyaluronan metabolic process, receptor-mediated endocytosis, small molecule metabolic process cytoplasm, external side of plasma membrane, integral to plasma membrane, plasma membrane Gram-negative bacterial cell surface binding, bacterial cell surface binding, hyaluronic acid binding, low-density lipoprotein particle binding, low-density lipoprotein receptor activity, protein disulfide oxidoreductase activity, scavenger receptor activity Human STAC UniProtKB UniProtKB {GO:0034605=GO_REF:0000019, GO:0035556=GO_REF:0000002, GO:0007165=PMID:8954993, GO:0046872=GO_REF:0000037, GO:0005829=PMID:8954993} Q99469 SH3 and cysteine-rich domain-containing protein protein 20120803 {GO:0034605=IEA, GO:0035556=IEA, GO:0007165=NAS, GO:0046872=IEA, GO:0005829=NAS} cellular response to heat, intracellular signal transduction, signal transduction cytosol metal ion binding Human STAC2 UniProtKB UniProtKB {GO:0035556=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q6ZMT1 SH3 and cysteine-rich domain-containing protein 2 protein 20130413 {GO:0035556=IEA, GO:0046872=IEA} intracellular signal transduction metal ion binding Human UniProtKB-KW:KW-0479 STAC3 IntAct UniProtKB {GO:0035556=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0042802=PMID:16189514} Q96MF2 SH3 and cysteine-rich domain-containing protein 3 protein 20130415 {GO:0035556=IEA, GO:0046872=IEA, GO:0042802=IPI} intracellular signal transduction identical protein binding, metal ion binding Human UniProtKB:Q96MF2 STAG1 HPA UniProtKB {GO:0005515=PMID:16682347, GO:0000236=Reactome:REACT_682, GO:0030054=GO_REF:0000052, GO:0005694=Reactome:REACT_150454, GO:0005634=GO_REF:0000052, GO:0005829=Reactome:REACT_150294, GO:0000084=Reactome:REACT_899, GO:0000910=Reactome:REACT_1932, GO:0007059=GO_REF:0000037, GO:0000087=Reactome:REACT_910, GO:0005654=Reactome:REACT_150456, GO:0000278=Reactome:REACT_152, GO:0000785=PMID:16682347, GO:0000090=Reactome:REACT_1275, GO:0000775=Reactome:REACT_150445} Q8WVM7 Cohesin subunit SA-1 protein 20101115 {GO:0005515=IPI, GO:0000236=TAS, GO:0030054=IDA, GO:0005694=TAS, GO:0005634=IDA, GO:0005829=TAS, GO:0000084=TAS, GO:0000910=TAS, GO:0007059=IEA, GO:0000087=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0000785=IDA, GO:0000090=TAS, GO:0000775=TAS} M phase of mitotic cell cycle, S phase of mitotic cell cycle, chromosome segregation, cytokinesis, mitotic anaphase, mitotic cell cycle, mitotic prometaphase cell junction, chromatin, chromosome, chromosome, centromeric region, cytosol, nucleoplasm, nucleus protein binding Human STAG2 BHF-UCL UniProtKB {GO:0005515=PMID:16682347, GO:0000236=Reactome:REACT_682, GO:0005694=Reactome:REACT_150454, GO:0032876=PMID:15917200, GO:0005634=PMID:9305759, GO:0005829=Reactome:REACT_150294, GO:0000084=Reactome:REACT_899, GO:0000910=Reactome:REACT_1932, GO:0007126=GO_REF:0000037, GO:0019827=GO_REF:0000019, GO:0000087=Reactome:REACT_910, GO:0007062=PMID:15917200, GO:0005654=Reactome:REACT_150456, GO:0000278=Reactome:REACT_152, GO:0000785=PMID:16682347, GO:0000090=Reactome:REACT_1275, GO:0000775=Reactome:REACT_150445} Q8N3U4 Cohesin subunit SA-2 protein 20100127 {GO:0005515=IPI, GO:0000236=TAS, GO:0005694=TAS, GO:0032876=IMP, GO:0005634=TAS, GO:0005829=TAS, GO:0000084=TAS, GO:0000910=TAS, GO:0007126=IEA, GO:0019827=IEA, GO:0000087=TAS, GO:0007062=IMP, GO:0005654=TAS, GO:0000278=TAS, GO:0000785=IDA, GO:0000090=TAS, GO:0000775=TAS} M phase of mitotic cell cycle, S phase of mitotic cell cycle, cytokinesis, meiosis, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, negative regulation of DNA endoreduplication, sister chromatid cohesion, stem cell maintenance chromatin, chromosome, chromosome, centromeric region, cytosol, nucleoplasm, nucleus protein binding Human STAG3 PINC UniProtKB {GO:0000795=PMID:10698974, GO:0007059=GO_REF:0000037, GO:0000802=GO_REF:0000019, GO:0030893=PMID:21242291, GO:0005634=PMID:10698974, GO:0007130=PMID:10698974, GO:0001673=GO_REF:0000019, GO:0000775=GO_REF:0000039} Q9UJ98 Cohesin subunit SA-3 protein 20030904 {GO:0000795=TAS, GO:0007059=IEA, GO:0000802=IEA, GO:0030893=IDA, GO:0005634=TAS, GO:0007130=TAS, GO:0001673=IEA, GO:0000775=IEA} chromosome segregation, synaptonemal complex assembly chromosome, centromeric region, male germ cell nucleus, meiotic cohesin complex, nucleus, synaptonemal complex, transverse filament Human STAM IntAct UniProtKB {GO:0005515=PMID:10383417, GO:0007165=PMID:8780729, GO:0007173=Reactome:REACT_9417, GO:0005070=PMID:8780729, GO:0031901=GO_REF:0000039, GO:0016197=Reactome:REACT_27258, GO:0042059=Reactome:REACT_12484, GO:0006886=GO_REF:0000002, GO:0016044=Reactome:REACT_11123, GO:0005829=Reactome:REACT_27272} Q92783 Signal transducing adapter molecule 1 protein 20130415 {GO:0005515=IPI, GO:0007165=TAS, GO:0007173=TAS, GO:0005070=TAS, GO:0031901=IEA, GO:0016197=TAS, GO:0042059=TAS, GO:0006886=IEA, GO:0016044=TAS, GO:0005829=TAS} cellular membrane organization, endosomal transport, epidermal growth factor receptor signaling pathway, intracellular protein transport, negative regulation of epidermal growth factor receptor signaling pathway, signal transduction cytosol, early endosome membrane SH3/SH2 adaptor activity, protein binding Human UniProtKB:O95630 STAM2 HPA UniProtKB {GO:0005515=PMID:19060904, GO:0005737=GO_REF:0000052, GO:0007173=Reactome:REACT_9417, GO:0031901=GO_REF:0000039, GO:0016197=Reactome:REACT_27258, GO:0005730=GO_REF:0000052, GO:0042059=Reactome:REACT_12484, GO:0005634=GO_REF:0000052, GO:0006886=GO_REF:0000002, GO:0016044=Reactome:REACT_11123, GO:0043231=GO_REF:0000052, GO:0005829=Reactome:REACT_27272} O75886 Signal transducing adapter molecule 2 protein 20111111 {GO:0005515=IPI, GO:0005737=IDA, GO:0007173=TAS, GO:0031901=IEA, GO:0016197=TAS, GO:0005730=IDA, GO:0042059=TAS, GO:0005634=IDA, GO:0006886=IEA, GO:0016044=TAS, GO:0043231=IDA, GO:0005829=TAS} cellular membrane organization, endosomal transport, epidermal growth factor receptor signaling pathway, intracellular protein transport, negative regulation of epidermal growth factor receptor signaling pathway cytoplasm, cytosol, early endosome membrane, intracellular membrane-bounded organelle, nucleolus, nucleus protein binding Human STAMBP HPA UniProtKB {GO:0005515=PMID:21988832, GO:0016579=PMID:18388320, GO:0043066=GO_REF:0000019, GO:0008284=PMID:10383417, GO:0004843=PMID:18388320, GO:0005886=GO_REF:0000052, GO:0000281=PMID:18388320, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0032154=PMID:18388320, GO:0007259=PMID:10383417, GO:0046872=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0006508=GO_REF:0000037, GO:0008237=GO_REF:0000037, GO:0005769=GO_REF:0000039} O95630 STAM-binding protein protein 20110516 {GO:0005515=IPI, GO:0016579=IMP, GO:0043066=IEA, GO:0008284=TAS, GO:0004843=IDA, GO:0005886=IDA, GO:0000281=IMP, GO:0005730=IDA, GO:0005634=IDA, GO:0032154=IDA, GO:0007259=TAS, GO:0046872=IEA, GO:0005737=IDA, GO:0006508=IEA, GO:0008237=IEA, GO:0005769=IEA} JAK-STAT cascade, cytokinesis after mitosis, negative regulation of apoptotic process, positive regulation of cell proliferation, protein deubiquitination, proteolysis cleavage furrow, cytoplasm, early endosome, nucleolus, nucleus, plasma membrane metal ion binding, metallopeptidase activity, protein binding, ubiquitin-specific protease activity Human STAMBPL1 IntAct UniProtKB {GO:0005515=PMID:21163940, GO:0006508=GO_REF:0000037, GO:0008233=GO_REF:0000038, GO:0046872=GO_REF:0000037, GO:0008237=GO_REF:0000037} Q96FJ0 AMSH-like protease protein 20130415 {GO:0005515=IPI, GO:0006508=IEA, GO:0008233=IEA, GO:0046872=IEA, GO:0008237=IEA} proteolysis metal ion binding, metallopeptidase activity, peptidase activity, protein binding Human UniProtKB:Q9H0A6 STAP1 HPA UniProtKB {GO:0005515=PMID:17936702, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006886=PMID:10518561, GO:0043231=GO_REF:0000052, GO:0005739=PMID:17936702, GO:0007165=PMID:10518561, GO:0043234=PMID:18468998, GO:0005737=PMID:17936702, GO:0005543=GO_REF:0000002, GO:0006944=PMID:10518561, GO:0005070=GO_REF:0000019, GO:0007169=GO_REF:0000019} Q9ULZ2 Signal-transducing adaptor protein 1 protein 20111111 {GO:0005515=IPI, GO:0005730=IDA, GO:0005634=IDA, GO:0006886=TAS, GO:0043231=IDA, GO:0005739=IDA, GO:0007165=TAS, GO:0043234=IDA, GO:0005737=IDA, GO:0005543=IEA, GO:0006944=TAS, GO:0005070=IEA, GO:0007169=IEA} cellular membrane fusion, intracellular protein transport, signal transduction, transmembrane receptor protein tyrosine kinase signaling pathway cytoplasm, intracellular membrane-bounded organelle, mitochondrion, nucleolus, nucleus, protein complex SH3/SH2 adaptor activity, phospholipid binding, protein binding Human STAP2 HPA UniProtKB {GO:0005515=PMID:16365431, GO:0005737=GO_REF:0000039, GO:0005543=GO_REF:0000002, GO:0005886=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0043231=GO_REF:0000052} Q9UGK3 Signal-transducing adaptor protein 2 protein 20101115 {GO:0005515=IPI, GO:0005737=IEA, GO:0005543=IEA, GO:0005886=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0043231=IDA} cytoplasm, intracellular membrane-bounded organelle, nucleolus, nucleus, plasma membrane phospholipid binding, protein binding Human STAR Reactome UniProtKB {GO:0042542=GO_REF:0000019, GO:0006694=PMID:7761400, GO:0043627=GO_REF:0000019, GO:0018963=GO_REF:0000019, GO:0006701=GO_REF:0000019, GO:0017143=GO_REF:0000019, GO:0006699=GO_REF:0000019, GO:0006703=GO_REF:0000019, GO:0071560=GO_REF:0000019, GO:0042747=GO_REF:0000019, GO:0005758=Reactome:REACT_10076, GO:0048168=GO_REF:0000019, GO:0060992=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0018958=GO_REF:0000019, GO:0030061=GO_REF:0000019, GO:0010288=GO_REF:0000019, GO:0051412=GO_REF:0000019, GO:0032869=GO_REF:0000019, GO:0071312=GO_REF:0000019, GO:0009635=GO_REF:0000019, GO:0044321=GO_REF:0000019, GO:0061370=GO_REF:0000019, GO:0071346=GO_REF:0000019, GO:0071872=GO_REF:0000019, GO:0007420=GO_REF:0000019, GO:0006700=Reactome:REACT_11038, GO:0016101=GO_REF:0000019, GO:0032367=GO_REF:0000019, GO:0043005=GO_REF:0000019, GO:0035457=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0017127=GO_REF:0000002, GO:0050810=GO_REF:0000019, GO:0018879=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0005829=GO_REF:0000019, GO:0071372=GO_REF:0000019, GO:0071373=GO_REF:0000019, GO:0015485=GO_REF:0000019, GO:0050769=GO_REF:0000019, GO:0010212=GO_REF:0000019, GO:0071378=GO_REF:0000019, GO:0071276=GO_REF:0000019, GO:0071333=GO_REF:0000019, GO:0008202=Reactome:REACT_11057, GO:0071236=GO_REF:0000019, GO:0008203=GO_REF:0000041, GO:0007584=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0044344=GO_REF:0000019, GO:0010628=GO_REF:0000019, GO:0050756=GO_REF:0000019, GO:0018894=GO_REF:0000019, GO:0071222=GO_REF:0000019, GO:0071320=GO_REF:0000019, GO:0008211=GO_REF:0000019, GO:0008584=GO_REF:0000019, GO:0035094=GO_REF:0000019, GO:0071549=GO_REF:0000019} P49675 Steroidogenic acute regulatory protein, mitochondrial protein 20130213 {GO:0042542=IEA, GO:0006694=TAS, GO:0043627=IEA, GO:0018963=IEA, GO:0006701=IEA, GO:0017143=IEA, GO:0006699=IEA, GO:0006703=IEA, GO:0071560=IEA, GO:0042747=IEA, GO:0005758=TAS, GO:0048168=IEA, GO:0060992=IEA, GO:0043025=IEA, GO:0018958=IEA, GO:0030061=IEA, GO:0010288=IEA, GO:0051412=IEA, GO:0032869=IEA, GO:0071312=IEA, GO:0009635=IEA, GO:0044321=IEA, GO:0061370=IEA, GO:0071346=IEA, GO:0071872=IEA, GO:0007420=IEA, GO:0006700=TAS, GO:0016101=IEA, GO:0032367=IEA, GO:0043005=IEA, GO:0035457=IEA, GO:0045471=IEA, GO:0017127=IEA, GO:0050810=IEA, GO:0018879=IEA, GO:0044281=TAS, GO:0005829=IEA, GO:0071372=IEA, GO:0071373=IEA, GO:0015485=IEA, GO:0050769=IEA, GO:0010212=IEA, GO:0071378=IEA, GO:0071276=IEA, GO:0071333=IEA, GO:0008202=TAS, GO:0071236=IEA, GO:0008203=IEA, GO:0007584=IEA, GO:0042493=IEA, GO:0044344=IEA, GO:0010628=IEA, GO:0050756=IEA, GO:0018894=IEA, GO:0071222=IEA, GO:0071320=IEA, GO:0008211=IEA, GO:0008584=IEA, GO:0035094=IEA, GO:0071549=IEA} C21-steroid hormone biosynthetic process, bile acid biosynthetic process, biphenyl metabolic process, brain development, cellular response to alkaloid, cellular response to antibiotic, cellular response to cAMP, cellular response to cadmium ion, cellular response to dexamethasone stimulus, cellular response to epinephrine stimulus, cellular response to fibroblast growth factor stimulus, cellular response to follicle-stimulating hormone stimulus, cellular response to glucose stimulus, cellular response to growth hormone stimulus, cellular response to insulin stimulus, cellular response to interferon-alpha, cellular response to interferon-gamma, cellular response to lipopolysaccharide, cellular response to luteinizing hormone stimulus, cellular response to transforming growth factor beta stimulus, cholesterol metabolic process, circadian sleep/wake cycle, REM sleep, dibenzo-p-dioxin metabolic process, diterpenoid metabolic process, estrogen biosynthetic process, fractalkine metabolic process, glucocorticoid metabolic process, insecticide metabolic process, intracellular cholesterol transport, male gonad development, phenol-containing compound metabolic process, phthalate metabolic process, positive regulation of gene expression, positive regulation of neurogenesis, progesterone biosynthetic process, regulation of neuronal synaptic plasticity, regulation of steroid biosynthetic process, response to corticosterone stimulus, response to drug, response to estrogen stimulus, response to ethanol, response to fungicide, response to herbicide, response to hydrogen peroxide, response to ionizing radiation, response to lead ion, response to leptin stimulus, response to nicotine, response to nutrient, small molecule metabolic process, steroid biosynthetic process, steroid metabolic process, testosterone biosynthetic process cytosol, mitochondrial crista, mitochondrial intermembrane space, neuron projection, neuronal cell body cholesterol binding, cholesterol transporter activity Human STARD10 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0016020=GO_REF:0000039, GO:0006869=GO_REF:0000037, GO:0042995=GO_REF:0000037, GO:0008289=GO_REF:0000037} Q9Y365 PCTP-like protein protein 20130413 {GO:0005737=IEA, GO:0016020=IEA, GO:0006869=IEA, GO:0042995=IEA, GO:0008289=IEA} lipid transport cell projection, cytoplasm, membrane lipid binding Human UniProtKB-SubCell:SL-0162 STARD13 IntAct UniProtKB {GO:0005515=PMID:14697242, GO:0005811=GO_REF:0000039, GO:0051056=Reactome:REACT_11051, GO:0031966=GO_REF:0000039, GO:0007264=Reactome:REACT_11044, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} Q9Y3M8 StAR-related lipid transfer protein 13 protein 20130415 {GO:0005515=IPI, GO:0005811=IEA, GO:0051056=TAS, GO:0031966=IEA, GO:0007264=TAS, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol, lipid particle, mitochondrial membrane GTPase activator activity, protein binding Human UniProtKB:Q86VP1 STARD3NL UniProtKB UniProtKB {GO:0031902=GO_REF:0000039, GO:0016021=GO_REF:0000037} O95772 MLN64 N-terminal domain homolog protein 20130413 {GO:0031902=IEA, GO:0016021=IEA} integral to membrane, late endosome membrane Human UniProtKB-SubCell:SL-0151 STARD4 UniProtKB UniProtKB {GO:0006869=GO_REF:0000037, GO:0008289=GO_REF:0000037} Q96DR4 StAR-related lipid transfer protein 4 protein 20130413 {GO:0006869=IEA, GO:0008289=IEA} lipid transport lipid binding Human UniProtKB-KW:KW-0446 STARD5 Reactome UniProtKB {GO:0006869=GO_REF:0000037, GO:0006700=Reactome:REACT_11038, GO:0044281=Reactome:REACT_111217, GO:0008202=Reactome:REACT_11057, GO:0005829=Reactome:REACT_9973, GO:0008289=GO_REF:0000037} Q9NSY2 StAR-related lipid transfer protein 5 protein 20130301 {GO:0006869=IEA, GO:0006700=TAS, GO:0044281=TAS, GO:0008202=TAS, GO:0005829=TAS, GO:0008289=IEA} C21-steroid hormone biosynthetic process, lipid transport, small molecule metabolic process, steroid metabolic process cytosol lipid binding Human STARD7 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039} Q9NQZ5 StAR-related lipid transfer protein 7, mitochondrial protein 20130413 {GO:0005739=IEA} mitochondrion Human UniProtKB-SubCell:SL-0173 STARD8 Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0007264=Reactome:REACT_11044, GO:0005925=GO_REF:0000039, GO:0005829=Reactome:REACT_9982, GO:0005096=GO_REF:0000037} Q92502 StAR-related lipid transfer protein 8 protein 20130301 {GO:0051056=TAS, GO:0007264=TAS, GO:0005925=IEA, GO:0005829=TAS, GO:0005096=IEA} regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol, focal adhesion GTPase activator activity Human STARD9 UniProtKB UniProtKB {GO:0008017=PMID:22153075, GO:0005737=PMID:22153075, GO:0005814=PMID:22153075, GO:0005875=GO_REF:0000002, GO:0008152=PMID:22153075, GO:0005634=PMID:22153075, GO:0003777=PMID:22153075, GO:0051225=PMID:22153075, GO:0005524=GO_REF:0000037, GO:0007018=GO_REF:0000002} Q9P2P6 StAR-related lipid transfer protein 9 protein 20111223 {GO:0008017=IDA, GO:0005737=IDA, GO:0005814=IDA, GO:0005875=IEA, GO:0008152=IDA, GO:0005634=IDA, GO:0003777=IDA, GO:0051225=IMP, GO:0005524=IEA, GO:0007018=IEA} metabolic process, microtubule-based movement, spindle assembly centriole, cytoplasm, microtubule associated complex, nucleus ATP binding, microtubule binding, microtubule motor activity Human STAT1 BHF-UCL UniProtKB {GO:0005515=PMID:21988832, GO:0000790=PMID:18035482, GO:0003700=PMID:10973496, GO:0000983=PMID:21268089, GO:0008015=GO_REF:0000024, GO:0019221=Reactome:REACT_25229, GO:0051591=GO_REF:0000024, GO:0042803=PMID:9630226, GO:0060334=Reactome:REACT_24980, GO:0051607=GO_REF:0000037, GO:0003690=PMID:9630226, GO:0060337=Reactome:REACT_25162, GO:0072308=GO_REF:0000024, GO:0060338=Reactome:REACT_25216, GO:0072136=GO_REF:0000024, GO:0031663=GO_REF:0000019, GO:0043124=PMID:10848577, GO:0060333=PMID:21268089, GO:0005164=PMID:10848577, GO:0005509=GO_REF:0000002, GO:0000122=GO_REF:0000024, GO:0000978=PMID:18035482, GO:0000979=PMID:21268089, GO:0033209=PMID:10848577, GO:0043542=PMID:16585190, GO:0005654=Reactome:REACT_111242, GO:0019899=PMID:22002246, GO:0045893=PMID:10973496, GO:0061326=PMID:20861313, GO:0030424=GO_REF:0000024, GO:0043434=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0060397=Reactome:REACT_111133, GO:0030425=GO_REF:0000024, GO:0005829=Reactome:REACT_121233, GO:0005737=GO_REF:0000052, GO:0004871=GO_REF:0000002, GO:0034097=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0042981=PMID:12108949, GO:0002053=GO_REF:0000024, GO:0006917=GO_REF:0000024, GO:0003340=GO_REF:0000024, GO:0007259=PMID:22002246, GO:0048661=GO_REF:0000024, GO:0006351=GO_REF:0000019, GO:0001937=PMID:16585190, GO:0019048=GO_REF:0000037, GO:0016525=PMID:16585190, GO:0043330=GO_REF:0000019, GO:0072162=GO_REF:0000024} P42224 Signal transducer and activator of transcription 1-alpha/beta protein 20121126 {GO:0005515=IPI, GO:0000790=IDA, GO:0003700=IDA, GO:0000983=IDA, GO:0008015=ISS, GO:0019221=TAS, GO:0051591=ISS, GO:0042803=IDA, GO:0060334=TAS, GO:0051607=IEA, GO:0003690=IDA, GO:0060337=TAS, GO:0072308=ISS, GO:0060338=TAS, GO:0072136=ISS, GO:0031663=IEA, GO:0043124=IMP, GO:0060333=IDA, GO:0005164=IPI, GO:0005509=IEA, GO:0000122=ISS, GO:0000978=IDA, GO:0000979=IDA, GO:0033209=IDA, GO:0043542=IMP, GO:0005654=TAS, GO:0019899=IPI, GO:0045893=IDA, GO:0061326=IMP, GO:0030424=ISS, GO:0043434=ISS, GO:0005634=IDA, GO:0060397=TAS, GO:0030425=ISS, GO:0005829=TAS, GO:0005737=IDA, GO:0004871=IEA, GO:0034097=ISS, GO:0005730=IDA, GO:0042981=TAS, GO:0002053=ISS, GO:0006917=ISS, GO:0003340=ISS, GO:0007259=IDA, GO:0048661=ISS, GO:0006351=IEA, GO:0001937=IMP, GO:0019048=IEA, GO:0016525=IMP, GO:0043330=IEA, GO:0072162=ISS} JAK-STAT cascade, JAK-STAT cascade involved in growth hormone signaling pathway, blood circulation, cytokine-mediated signaling pathway, defense response to virus, endothelial cell migration, induction of apoptosis, interferon-gamma-mediated signaling pathway, lipopolysaccharide-mediated signaling pathway, metanephric mesenchymal cell differentiation, metanephric mesenchymal cell proliferation involved in metanephros development, negative regulation of I-kappaB kinase/NF-kappaB cascade, negative regulation of angiogenesis, negative regulation of endothelial cell proliferation, negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis, negative regulation of metanephric nephron tubule epithelial cell differentiation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of mesenchymal cell proliferation, positive regulation of smooth muscle cell proliferation, positive regulation of transcription, DNA-dependent, regulation of apoptotic process, regulation of interferon-gamma-mediated signaling pathway, regulation of type I interferon-mediated signaling pathway, renal tubule development, response to cAMP, response to cytokine stimulus, response to exogenous dsRNA, response to peptide hormone stimulus, transcription, DNA-dependent, tumor necrosis factor-mediated signaling pathway, type I interferon-mediated signaling pathway, virus-host interaction axon, cytoplasm, cytosol, dendrite, nuclear chromatin, nucleolus, nucleoplasm, nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II core promoter sequence-specific DNA binding, RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity, calcium ion binding, double-stranded DNA binding, enzyme binding, protein binding, protein homodimerization activity, sequence-specific DNA binding transcription factor activity, signal transducer activity, tumor necrosis factor receptor binding Human STAT2 HPA UniProtKB {GO:0005515=PMID:21903422, GO:0003700=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0006357=PMID:9020188, GO:0019221=Reactome:REACT_25229, GO:0005509=GO_REF:0000002, GO:0005634=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0007259=PMID:9020188, GO:0006351=GO_REF:0000037, GO:0005829=Reactome:REACT_25401, GO:0005737=GO_REF:0000052, GO:0051607=GO_REF:0000037, GO:0060337=Reactome:REACT_25162, GO:0060338=Reactome:REACT_25216, GO:0019048=GO_REF:0000037, GO:0005654=Reactome:REACT_25169, GO:0004871=GO_REF:0000002} P52630 Signal transducer and activator of transcription 2 protein 20100326 {GO:0005515=IPI, GO:0003700=IEA, GO:0005886=IDA, GO:0006357=TAS, GO:0019221=TAS, GO:0005509=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0007259=TAS, GO:0006351=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0051607=IEA, GO:0060337=TAS, GO:0060338=TAS, GO:0019048=IEA, GO:0005654=TAS, GO:0004871=IEA} JAK-STAT cascade, cytokine-mediated signaling pathway, defense response to virus, regulation of transcription from RNA polymerase II promoter, regulation of type I interferon-mediated signaling pathway, transcription, DNA-dependent, type I interferon-mediated signaling pathway, virus-host interaction cytoplasm, cytosol, nucleoplasm, nucleus, plasma membrane DNA binding, calcium ion binding, protein binding, sequence-specific DNA binding transcription factor activity, signal transducer activity Human STAT3 BHF-UCL UniProtKB {GO:0001754=GO_REF:0000024, GO:0005515=PMID:21988832, GO:0001659=GO_REF:0000024, GO:0003700=PMID:8675499, GO:0044212=PMID:17324931, GO:0000981=GO_REF:0000019, GO:0048708=GO_REF:0000024, GO:0019221=PMID:15664994, GO:0006606=PMID:18234692, GO:0046983=GO_REF:0000024, GO:0004879=PMID:17324931, GO:0070102=PMID:17324931, GO:0032355=PMID:12552091, GO:0001103=PMID:22783022, GO:0045747=GO_REF:0000024, GO:0019901=GO_REF:0000024, GO:0005509=GO_REF:0000002, GO:0006953=GO_REF:0000019, GO:0000122=PMID:8675499, GO:0019953=GO_REF:0000024, GO:0005654=Reactome:REACT_111242, GO:0045893=GO_REF:0000024, GO:0031730=GO_REF:0000019, GO:0008134=PMID:15664994, GO:0005886=GO_REF:0000024, GO:0008283=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0006928=PMID:9670957, GO:0005634=PMID:22783022, GO:0060396=PMID:10925297, GO:0035259=GO_REF:0000019, GO:0060397=PMID:12552091, GO:0032870=PMID:12552091, GO:0005829=Reactome:REACT_121233, GO:0005737=PMID:22783022, GO:0045944=PMID:17324931, GO:0040014=GO_REF:0000019, GO:0004871=PMID:7512451, GO:0034097=GO_REF:0000019, GO:0006355=PMID:15664994, GO:0048011=Reactome:REACT_11061, GO:0006357=GO_REF:0000024, GO:0042493=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0042593=GO_REF:0000024, GO:0007259=PMID:15664994, GO:0003677=GO_REF:0000024, GO:0007399=PMID:10205054, GO:0043565=GO_REF:0000019, GO:0007165=PMID:7512451, GO:0060019=GO_REF:0000024, GO:0019827=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0042755=GO_REF:0000024, GO:0030522=PMID:17324931} P40763 Signal transducer and activator of transcription 3 protein 20121122 {GO:0001754=ISS, GO:0005515=IPI, GO:0001659=ISS, GO:0003700=TAS, GO:0044212=IDA, GO:0000981=IEA, GO:0048708=ISS, GO:0019221=NAS, GO:0006606=IDA, GO:0046983=ISS, GO:0004879=IDA, GO:0070102=IDA, GO:0032355=IDA, GO:0001103=IPI, GO:0045747=ISS, GO:0019901=ISS, GO:0005509=IEA, GO:0006953=IEA, GO:0000122=TAS, GO:0019953=ISS, GO:0005654=TAS, GO:0045893=ISS, GO:0031730=IEA, GO:0008134=IPI, GO:0005886=ISS, GO:0008283=IEA, GO:0045471=IEA, GO:0006928=TAS, GO:0005634=IDA, GO:0060396=IDA, GO:0035259=IEA, GO:0060397=IDA, GO:0032870=IDA, GO:0005829=TAS, GO:0005737=IDA, GO:0045944=IDA, GO:0040014=IEA, GO:0004871=TAS, GO:0034097=IEA, GO:0006355=IDA, GO:0048011=TAS, GO:0006357=ISS, GO:0042493=IEA, GO:0005730=IDA, GO:0042593=ISS, GO:0007259=TAS, GO:0003677=ISS, GO:0007399=TAS, GO:0043565=IEA, GO:0007165=TAS, GO:0060019=ISS, GO:0019827=IEA, GO:0019048=IEA, GO:0042755=ISS, GO:0030522=IDA} JAK-STAT cascade, JAK-STAT cascade involved in growth hormone signaling pathway, acute-phase response, astrocyte differentiation, cell proliferation, cellular component movement, cellular response to hormone stimulus, cytokine-mediated signaling pathway, eating behavior, eye photoreceptor cell differentiation, glucose homeostasis, growth hormone receptor signaling pathway, interleukin-6-mediated signaling pathway, intracellular receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, nervous system development, neurotrophin TRK receptor signaling pathway, positive regulation of Notch signaling pathway, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein import into nucleus, radial glial cell differentiation, regulation of multicellular organism growth, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, response to cytokine stimulus, response to drug, response to estradiol stimulus, response to ethanol, sexual reproduction, signal transduction, stem cell maintenance, temperature homeostasis, virus-host interaction cytoplasm, cytosol, nucleolus, nucleoplasm, nucleus, plasma membrane CCR5 chemokine receptor binding, DNA binding, RNA polymerase II repressing transcription factor binding, calcium ion binding, glucocorticoid receptor binding, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, protein binding, protein dimerization activity, protein kinase binding, sequence-specific DNA binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity, signal transducer activity, transcription factor binding, transcription regulatory region DNA binding Human STAT4 HPA UniProtKB {GO:0003700=GO_REF:0000002, GO:0008283=GO_REF:0000019, GO:0019221=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0007259=PMID:9284918, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0045944=GO_REF:0000019, GO:0006468=GO_REF:0000019, GO:0004871=GO_REF:0000002} Q14765 Signal transducer and activator of transcription 4 protein 20080818 {GO:0003700=IEA, GO:0008283=IEA, GO:0019221=IEA, GO:0005509=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0007259=TAS, GO:0006351=IEA, GO:0043565=IEA, GO:0005737=IEA, GO:0045944=IEA, GO:0006468=IEA, GO:0004871=IEA} JAK-STAT cascade, cell proliferation, cytokine-mediated signaling pathway, positive regulation of transcription from RNA polymerase II promoter, protein phosphorylation, transcription, DNA-dependent cytoplasm, nucleolus, nucleus calcium ion binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, signal transducer activity NOT Human STAT5A HPA UniProtKB {GO:0033026=GO_REF:0000019, GO:0005515=PMID:16819511, GO:0003700=GO_REF:0000002, GO:0006549=GO_REF:0000024, GO:0019530=GO_REF:0000024, GO:0019915=GO_REF:0000019, GO:0019221=GO_REF:0000019, GO:0001553=GO_REF:0000019, GO:0030155=GO_REF:0000019, GO:0048541=GO_REF:0000019, GO:0060376=GO_REF:0000019, GO:0043029=GO_REF:0000019, GO:0033077=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:0046543=GO_REF:0000019, GO:0046544=GO_REF:0000019, GO:0045588=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0018108=GO_REF:0000019, GO:0046449=GO_REF:0000024, GO:0032825=GO_REF:0000019, GO:0019218=GO_REF:0000019, GO:0000979=GO_REF:0000019, GO:0045086=GO_REF:0000019, GO:0045931=GO_REF:0000019, GO:0045647=GO_REF:0000019, GO:0006600=GO_REF:0000024, GO:0005654=Reactome:REACT_115942, GO:0000255=GO_REF:0000024, GO:0045579=GO_REF:0000019, GO:0043434=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0060397=Reactome:REACT_111133, GO:0005829=Reactome:REACT_121048, GO:0042104=GO_REF:0000019, GO:0006101=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0030856=GO_REF:0000019, GO:0006105=GO_REF:0000024, GO:0045944=GO_REF:0000019, GO:0040014=GO_REF:0000024, GO:0006103=GO_REF:0000024, GO:0006631=GO_REF:0000024, GO:0006573=GO_REF:0000024, GO:0001779=GO_REF:0000019, GO:0040018=GO_REF:0000019, GO:0004871=GO_REF:0000002, GO:0006357=PMID:8631883, GO:0060742=GO_REF:0000019, GO:0061180=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0006107=GO_REF:0000024, GO:0060740=GO_REF:0000019, GO:0007259=PMID:7719937, GO:0006351=GO_REF:0000037, GO:0007595=GO_REF:0000019, GO:0045954=GO_REF:0000019, GO:0050729=GO_REF:0000019, GO:0070668=GO_REF:0000019} Q8WWS9 Signal transducer and activator of transcription 5A protein 20101115 {GO:0033026=IEA, GO:0005515=IPI, GO:0003700=IEA, GO:0006549=ISS, GO:0019530=ISS, GO:0019915=IEA, GO:0019221=IEA, GO:0001553=IEA, GO:0030155=IEA, GO:0048541=IEA, GO:0060376=IEA, GO:0043029=IEA, GO:0033077=IEA, GO:0007565=IEA, GO:0046543=IEA, GO:0046544=IEA, GO:0045588=IEA, GO:0005509=IEA, GO:0018108=IEA, GO:0046449=ISS, GO:0032825=IEA, GO:0019218=IEA, GO:0000979=IEA, GO:0045086=IEA, GO:0045931=IEA, GO:0045647=IEA, GO:0006600=ISS, GO:0005654=TAS, GO:0000255=ISS, GO:0045579=IEA, GO:0043434=IEA, GO:0005634=IDA, GO:0060397=TAS, GO:0005829=TAS, GO:0042104=IEA, GO:0006101=ISS, GO:0005737=IDA, GO:0030856=IEA, GO:0006105=ISS, GO:0045944=IEA, GO:0040014=ISS, GO:0006103=ISS, GO:0006631=ISS, GO:0006573=ISS, GO:0001779=IEA, GO:0040018=IEA, GO:0004871=IEA, GO:0006357=TAS, GO:0060742=IEA, GO:0061180=IEA, GO:0005730=IDA, GO:0006107=ISS, GO:0060740=IEA, GO:0007259=TAS, GO:0006351=IEA, GO:0007595=IEA, GO:0045954=IEA, GO:0050729=IEA, GO:0070668=IEA} 2-oxoglutarate metabolic process, JAK-STAT cascade, JAK-STAT cascade involved in growth hormone signaling pathway, Peyer's patch development, T cell differentiation in thymus, T cell homeostasis, allantoin metabolic process, citrate metabolic process, creatine metabolic process, creatinine metabolic process, cytokine-mediated signaling pathway, development of secondary female sexual characteristics, development of secondary male sexual characteristics, epithelial cell differentiation involved in prostate gland development, fatty acid metabolic process, female pregnancy, isoleucine metabolic process, lactation, lipid storage, luteinization, mammary gland epithelium development, natural killer cell differentiation, negative regulation of erythrocyte differentiation, negative regulation of mast cell apoptotic process, oxaloacetate metabolic process, peptidyl-tyrosine phosphorylation, positive regulation of B cell differentiation, positive regulation of activated T cell proliferation, positive regulation of gamma-delta T cell differentiation, positive regulation of inflammatory response, positive regulation of interleukin-2 biosynthetic process, positive regulation of mast cell differentiation, positive regulation of mast cell proliferation, positive regulation of mitotic cell cycle, positive regulation of multicellular organism growth, positive regulation of natural killer cell differentiation, positive regulation of natural killer cell mediated cytotoxicity, positive regulation of transcription from RNA polymerase II promoter, prostate gland epithelium morphogenesis, regulation of cell adhesion, regulation of epithelial cell differentiation, regulation of multicellular organism growth, regulation of steroid metabolic process, regulation of transcription from RNA polymerase II promoter, response to peptide hormone stimulus, succinate metabolic process, taurine metabolic process, transcription, DNA-dependent, valine metabolic process cytoplasm, cytosol, nucleolus, nucleoplasm, nucleus RNA polymerase II core promoter sequence-specific DNA binding, calcium ion binding, protein binding, sequence-specific DNA binding transcription factor activity, signal transducer activity Human STAT5B BHF-UCL UniProtKB {GO:0005515=PMID:21106534, GO:0003700=GO_REF:0000019, GO:0006549=GO_REF:0000024, GO:0006366=GO_REF:0000019, GO:0019530=GO_REF:0000024, GO:0019915=GO_REF:0000019, GO:0019221=GO_REF:0000019, GO:0001553=GO_REF:0000019, GO:0032819=GO_REF:0000019, GO:0030155=GO_REF:0000019, GO:0048541=GO_REF:0000019, GO:0003690=GO_REF:0000019, GO:0070670=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0070672=GO_REF:0000019, GO:0043029=GO_REF:0000019, GO:0032355=PMID:12552091, GO:0007565=GO_REF:0000019, GO:0033077=GO_REF:0000019, GO:0046543=GO_REF:0000019, GO:0046544=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0045588=GO_REF:0000019, GO:0006953=GO_REF:0000019, GO:0032825=GO_REF:0000019, GO:0046449=GO_REF:0000024, GO:0019218=GO_REF:0000019, GO:0000979=GO_REF:0000019, GO:0001889=GO_REF:0000019, GO:0045086=GO_REF:0000019, GO:0045931=GO_REF:0000019, GO:0045647=GO_REF:0000019, GO:0006600=GO_REF:0000024, GO:0042448=GO_REF:0000019, GO:0005654=Reactome:REACT_111242, GO:0000255=GO_REF:0000024, GO:0045471=GO_REF:0000019, GO:0045579=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0035259=PMID:12552091, GO:0060397=PMID:12552091, GO:0032870=PMID:12552091, GO:0005829=Reactome:REACT_121048, GO:0006101=GO_REF:0000024, GO:0042104=GO_REF:0000019, GO:0030856=GO_REF:0000019, GO:0006105=GO_REF:0000024, GO:0045944=GO_REF:0000024, GO:0040014=GO_REF:0000024, GO:0006103=GO_REF:0000024, GO:0006631=GO_REF:0000024, GO:0006573=GO_REF:0000024, GO:0001779=GO_REF:0000019, GO:0004871=GO_REF:0000019, GO:0040018=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0006357=PMID:8631883, GO:0006107=GO_REF:0000024, GO:0007259=PMID:8631883, GO:0048661=GO_REF:0000019, GO:0007595=GO_REF:0000019, GO:0050729=GO_REF:0000019, GO:0045954=GO_REF:0000019, GO:0070669=GO_REF:0000019, GO:0051272=GO_REF:0000019} P51692 Signal transducer and activator of transcription 5B protein 20090114 {GO:0005515=IPI, GO:0003700=IEA, GO:0006549=ISS, GO:0006366=IEA, GO:0019530=ISS, GO:0019915=IEA, GO:0019221=IEA, GO:0001553=IEA, GO:0032819=IEA, GO:0030155=IEA, GO:0048541=IEA, GO:0003690=IEA, GO:0070670=IEA, GO:0032496=IEA, GO:0070672=IEA, GO:0043029=IEA, GO:0032355=IDA, GO:0007565=IEA, GO:0033077=IEA, GO:0046543=IEA, GO:0046544=IEA, GO:0005509=IEA, GO:0045588=IEA, GO:0006953=IEA, GO:0032825=IEA, GO:0046449=ISS, GO:0019218=IEA, GO:0000979=IEA, GO:0001889=IEA, GO:0045086=IEA, GO:0045931=IEA, GO:0045647=IEA, GO:0006600=ISS, GO:0042448=IEA, GO:0005654=TAS, GO:0000255=ISS, GO:0045471=IEA, GO:0045579=IEA, GO:0005634=IEA, GO:0035259=IPI, GO:0060397=IDA, GO:0032870=IDA, GO:0005829=TAS, GO:0006101=ISS, GO:0042104=IEA, GO:0030856=IEA, GO:0006105=ISS, GO:0045944=ISS, GO:0040014=ISS, GO:0006103=ISS, GO:0006631=ISS, GO:0006573=ISS, GO:0001779=IEA, GO:0004871=IEA, GO:0040018=IEA, GO:0001666=IEA, GO:0043066=IEA, GO:0006357=TAS, GO:0006107=ISS, GO:0007259=TAS, GO:0048661=IEA, GO:0007595=IEA, GO:0050729=IEA, GO:0045954=IEA, GO:0070669=IEA, GO:0051272=IEA} 2-oxoglutarate metabolic process, JAK-STAT cascade, JAK-STAT cascade involved in growth hormone signaling pathway, Peyer's patch development, T cell differentiation in thymus, T cell homeostasis, acute-phase response, allantoin metabolic process, cellular response to hormone stimulus, citrate metabolic process, creatine metabolic process, creatinine metabolic process, cytokine-mediated signaling pathway, development of secondary female sexual characteristics, development of secondary male sexual characteristics, fatty acid metabolic process, female pregnancy, isoleucine metabolic process, lactation, lipid storage, liver development, luteinization, natural killer cell differentiation, negative regulation of apoptotic process, negative regulation of erythrocyte differentiation, oxaloacetate metabolic process, positive regulation of B cell differentiation, positive regulation of activated T cell proliferation, positive regulation of cellular component movement, positive regulation of gamma-delta T cell differentiation, positive regulation of inflammatory response, positive regulation of interleukin-2 biosynthetic process, positive regulation of mitotic cell cycle, positive regulation of multicellular organism growth, positive regulation of natural killer cell differentiation, positive regulation of natural killer cell mediated cytotoxicity, positive regulation of natural killer cell proliferation, positive regulation of smooth muscle cell proliferation, positive regulation of transcription from RNA polymerase II promoter, progesterone metabolic process, regulation of cell adhesion, regulation of epithelial cell differentiation, regulation of multicellular organism growth, regulation of steroid metabolic process, regulation of transcription from RNA polymerase II promoter, response to estradiol stimulus, response to ethanol, response to hypoxia, response to interleukin-15, response to interleukin-2, response to interleukin-4, response to lipopolysaccharide, succinate metabolic process, taurine metabolic process, transcription from RNA polymerase II promoter, valine metabolic process cytosol, nucleoplasm, nucleus RNA polymerase II core promoter sequence-specific DNA binding, calcium ion binding, double-stranded DNA binding, glucocorticoid receptor binding, protein binding, sequence-specific DNA binding transcription factor activity, signal transducer activity Human STAT6 ENSEMBL UniProtKB {GO:0005515=PMID:22000020, GO:0000790=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0006357=PMID:8810328, GO:0048295=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0019221=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000122=GO_REF:0000019, GO:0000979=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0042802=PMID:22000020, GO:0005829=Reactome:REACT_16982, GO:0060443=GO_REF:0000019, GO:0033598=GO_REF:0000019, GO:0007165=PMID:10747856, GO:0005737=GO_REF:0000019, GO:0002829=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0004871=GO_REF:0000002, GO:0002296=GO_REF:0000019} Q5FBW6 Signal transducer and activator of transcription 6 protein 20130413 {GO:0005515=IPI, GO:0000790=IEA, GO:0003700=IEA, GO:0006357=TAS, GO:0048295=IEA, GO:0005509=IEA, GO:0019221=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0000122=IEA, GO:0000979=IEA, GO:0006351=IEA, GO:0042802=IPI, GO:0005829=TAS, GO:0060443=IEA, GO:0033598=IEA, GO:0007165=TAS, GO:0005737=IEA, GO:0002829=IEA, GO:0042127=IEA, GO:0045944=IEA, GO:0004871=IEA, GO:0002296=IEA} T-helper 1 cell lineage commitment, cytokine-mediated signaling pathway, mammary gland epithelial cell proliferation, mammary gland morphogenesis, negative regulation of transcription from RNA polymerase II promoter, negative regulation of type 2 immune response, positive regulation of isotype switching to IgE isotypes, positive regulation of transcription from RNA polymerase II promoter, regulation of cell proliferation, regulation of transcription from RNA polymerase II promoter, signal transduction, transcription, DNA-dependent cytoplasm, cytosol, nuclear chromatin, nucleolus, nucleus RNA polymerase II core promoter sequence-specific DNA binding, calcium ion binding, identical protein binding, protein binding, sequence-specific DNA binding transcription factor activity, signal transducer activity Human Ensembl:ENSMUSP00000089708 STATH IntAct UniProtKB {GO:0005515=PMID:16203048, GO:0030345=PMID:1718282, GO:0001503=PMID:1313424, GO:0030197=PMID:1718282, GO:0046848=PMID:1741693, GO:0005576=PMID:1718282, GO:0030502=PMID:1313424, GO:0031214=GO_REF:0000037, GO:0046541=PMID:1718282} P02808 Statherin protein 20130415 {GO:0005515=IPI, GO:0030345=NAS, GO:0001503=TAS, GO:0030197=NAS, GO:0046848=NAS, GO:0005576=NAS, GO:0030502=NAS, GO:0031214=IEA, GO:0046541=NAS} biomineral tissue development, negative regulation of bone mineralization, ossification, saliva secretion extracellular region extracellular matrix constituent, lubricant activity, hydroxyapatite binding, protein binding, structural constituent of tooth enamel Human UniProtKB:Q8TAX7 STAU1 InterPro UniProtKB {GO:0005515=PMID:15680326, GO:0005791=GO_REF:0000039, GO:0003725=GO_REF:0000002, GO:0005737=PMID:19029303, GO:0008298=GO_REF:0000019, GO:0010494=GO_REF:0000024, GO:0005875=PMID:10022909} Q5JW30 Double-stranded RNA-binding protein Staufen homolog 1 protein 20130413 {GO:0005515=IPI, GO:0005791=IEA, GO:0003725=IEA, GO:0005737=IDA, GO:0008298=IEA, GO:0010494=ISS, GO:0005875=TAS} intracellular mRNA localization cytoplasm, cytoplasmic stress granule, microtubule associated complex, rough endoplasmic reticulum double-stranded RNA binding, protein binding Human InterPro:IPR001159 STAU2 IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0003725=GO_REF:0000002, GO:0005783=GO_REF:0000039, GO:0005874=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0006810=GO_REF:0000037} Q9NUL3 Double-stranded RNA-binding protein Staufen homolog 2 protein 20130415 {GO:0005515=IPI, GO:0003725=IEA, GO:0005783=IEA, GO:0005874=IEA, GO:0005730=IEA, GO:0006810=IEA} transport endoplasmic reticulum, microtubule, nucleolus double-stranded RNA binding, protein binding Human UniProtKB:Q96C10 STBD1 IntAct UniProtKB {GO:0005515=PMID:20562859, GO:0006936=PMID:9794794, GO:0016020=PMID:9794794, GO:0005887=PMID:9794794, GO:2001070=GO_REF:0000002} O95210 Starch-binding domain-containing protein 1 protein 20130415 {GO:0005515=IPI, GO:0006936=TAS, GO:0016020=TAS, GO:0005887=TAS, GO:2001070=IEA} muscle contraction integral to plasma membrane, membrane protein binding, starch binding Human UniProtKB:Q9H0R8 STC2 PINC UniProtKB {GO:0005794=GO_REF:0000019, GO:0007584=PMID:9753616, GO:0005783=GO_REF:0000019, GO:0007566=GO_REF:0000019, GO:0007267=PMID:9753616, GO:0006874=GO_REF:0000019, GO:0043434=GO_REF:0000019, GO:0071456=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0033280=GO_REF:0000019, GO:2001256=GO_REF:0000019, GO:0030968=GO_REF:0000019, GO:0046697=GO_REF:0000019, GO:0005179=GO_REF:0000037, GO:0040015=GO_REF:0000019, GO:0006979=GO_REF:0000019, GO:0007166=PMID:9753616} O76061 Stanniocalcin-2 protein 20030904 {GO:0005794=IEA, GO:0007584=TAS, GO:0005783=IEA, GO:0007566=IEA, GO:0007267=TAS, GO:0006874=IEA, GO:0043434=IEA, GO:0071456=IEA, GO:0005576=IEA, GO:0033280=IEA, GO:2001256=IEA, GO:0030968=IEA, GO:0046697=IEA, GO:0005179=IEA, GO:0040015=IEA, GO:0006979=IEA, GO:0007166=TAS} cell surface receptor signaling pathway, cell-cell signaling, cellular calcium ion homeostasis, cellular response to hypoxia, decidualization, embryo implantation, endoplasmic reticulum unfolded protein response, negative regulation of multicellular organism growth, regulation of store-operated calcium entry, response to nutrient, response to oxidative stress, response to peptide hormone stimulus, response to vitamin D Golgi apparatus, endoplasmic reticulum, extracellular region hormone activity Human STEAP1 PINC UniProtKB {GO:0005215=PMID:10588738, GO:0005886=PMID:10588738, GO:0005911=PMID:10588738, GO:0005887=PMID:10588738, GO:0016491=GO_REF:0000037, GO:0022900=GO_REF:0000037, GO:0055072=GO_REF:0000037, GO:0010008=GO_REF:0000039, GO:0046872=GO_REF:0000037, GO:0015267=PMID:10588738, GO:0006811=GO_REF:0000037} Q9UHE8 Metalloreductase STEAP1 protein 20030904 {GO:0005215=TAS, GO:0005886=TAS, GO:0005911=TAS, GO:0005887=TAS, GO:0016491=IEA, GO:0022900=IEA, GO:0055072=IEA, GO:0010008=IEA, GO:0046872=IEA, GO:0015267=TAS, GO:0006811=IEA} electron transport chain, ion transport, iron ion homeostasis cell-cell junction, endosome membrane, integral to plasma membrane, plasma membrane channel activity, metal ion binding, oxidoreductase activity, transporter activity Human STEAP2 UniProtKB UniProtKB {GO:0005215=PMID:12095985, GO:0005886=PMID:12095985, GO:0006893=PMID:12095985, GO:0055072=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0005829=PMID:12095985, GO:0006897=PMID:12095985, GO:0045055=PMID:12095985, GO:0030173=PMID:12095985, GO:0016491=GO_REF:0000037, GO:0009725=PMID:12095985, GO:0022900=GO_REF:0000037, GO:0030140=PMID:12095985, GO:0010008=GO_REF:0000039, GO:0005769=PMID:12095985, GO:0006811=GO_REF:0000037} Q8NFT2 Metalloreductase STEAP2 protein 20051019 {GO:0005215=IDA, GO:0005886=IDA, GO:0006893=IDA, GO:0055072=IEA, GO:0046872=IEA, GO:0005829=IDA, GO:0006897=IDA, GO:0045055=IDA, GO:0030173=IDA, GO:0016491=IEA, GO:0009725=IDA, GO:0022900=IEA, GO:0030140=IDA, GO:0010008=IEA, GO:0005769=IDA, GO:0006811=IEA} Golgi to plasma membrane transport, electron transport chain, endocytosis, ion transport, iron ion homeostasis, regulated secretory pathway, response to hormone stimulus cytosol, early endosome, endosome membrane, integral to Golgi membrane, plasma membrane, trans-Golgi network transport vesicle metal ion binding, oxidoreductase activity, transporter activity Human STEAP3 Reactome UniProtKB {GO:0005515=PMID:22624035, GO:0009306=PMID:15319436, GO:0000293=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0005771=PMID:15319436, GO:0006915=GO_REF:0000037, GO:0006917=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0046872=GO_REF:0000037, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0007049=GO_REF:0000037, GO:0016491=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0010008=Reactome:REACT_24919} Q658P3 Metalloreductase STEAP3 protein 20130301 {GO:0005515=IPI, GO:0009306=IDA, GO:0000293=IEA, GO:0005886=IEA, GO:0005771=IDA, GO:0006915=IEA, GO:0006917=IEA, GO:0055085=TAS, GO:0046872=IEA, GO:0006879=TAS, GO:0033572=TAS, GO:0007049=IEA, GO:0016491=IEA, GO:0016021=IEA, GO:0010008=TAS} apoptotic process, cell cycle, cellular iron ion homeostasis, induction of apoptosis, protein secretion, transferrin transport, transmembrane transport endosome membrane, integral to membrane, multivesicular body, plasma membrane ferric-chelate reductase activity, metal ion binding, oxidoreductase activity, protein binding Human STEAP4 UniProtKB UniProtKB {GO:0005886=GO_REF:0000024, GO:0000139=GO_REF:0000039, GO:0016491=GO_REF:0000037, GO:0045444=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0055072=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0006811=GO_REF:0000037} Q687X5 Metalloreductase STEAP4 protein 20070914 {GO:0005886=ISS, GO:0000139=IEA, GO:0016491=IEA, GO:0045444=ISS, GO:0016021=IEA, GO:0055072=IEA, GO:0046872=IEA, GO:0006811=IEA} fat cell differentiation, ion transport, iron ion homeostasis Golgi membrane, integral to membrane, plasma membrane metal ion binding, oxidoreductase activity Human UniProtKB:Q923B6 STIL BHF-UCL UniProtKB {GO:0005813=PMID:21399614, GO:0043066=GO_REF:0000024, GO:0007368=GO_REF:0000024, GO:0033504=GO_REF:0000024, GO:0008283=PMID:8825637, GO:0001843=GO_REF:0000024, GO:0001701=GO_REF:0000024, GO:0005829=GO_REF:0000039, GO:0007224=GO_REF:0000024, GO:0001947=GO_REF:0000024, GO:0000578=GO_REF:0000024, GO:0035264=GO_REF:0000024, GO:0021915=GO_REF:0000024, GO:0030900=GO_REF:0000024, GO:0030903=GO_REF:0000024} Q15468 SCL-interrupting locus protein protein 20110830 {GO:0005813=IDA, GO:0043066=ISS, GO:0007368=ISS, GO:0033504=ISS, GO:0008283=TAS, GO:0001843=ISS, GO:0001701=ISS, GO:0005829=IEA, GO:0007224=ISS, GO:0001947=ISS, GO:0000578=ISS, GO:0035264=ISS, GO:0021915=ISS, GO:0030900=ISS, GO:0030903=ISS} cell proliferation, determination of left/right symmetry, embryonic axis specification, floor plate development, forebrain development, heart looping, in utero embryonic development, multicellular organism growth, negative regulation of apoptotic process, neural tube closure, neural tube development, notochord development, smoothened signaling pathway centrosome, cytosol Human UniProtKB:Q60988 STIM1 HPA UniProtKB {GO:0005515=PMID:20418871, GO:0032541=PMID:22586105, GO:0005513=PMID:16005298, GO:0005783=GO_REF:0000052, GO:0005874=GO_REF:0000037, GO:0005509=PMID:16005298, GO:0030176=PMID:22586105, GO:0042802=PMID:20418871, GO:0043234=GO_REF:0000019, GO:0032237=PMID:16005298, GO:0051010=PMID:19632184, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:16208375, GO:0005789=Reactome:REACT_118808, GO:0051924=PMID:16005298, GO:0006816=GO_REF:0000037, GO:0006812=GO_REF:0000019} Q13586 Stromal interaction molecule 1 protein 20081203 {GO:0005515=IPI, GO:0032541=IDA, GO:0005513=IDA, GO:0005783=IDA, GO:0005874=IEA, GO:0005509=IDA, GO:0030176=IDA, GO:0042802=IPI, GO:0043234=IEA, GO:0032237=IDA, GO:0051010=IDA, GO:0007596=TAS, GO:0005887=IDA, GO:0005789=TAS, GO:0051924=IDA, GO:0006816=IEA, GO:0006812=IEA} activation of store-operated calcium channel activity, blood coagulation, calcium ion transport, cation transport, detection of calcium ion, regulation of calcium ion transport cortical endoplasmic reticulum, endoplasmic reticulum, endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane, integral to plasma membrane, microtubule, protein complex calcium ion binding, identical protein binding, microtubule plus-end binding, protein binding Human STIM2 IntAct UniProtKB {GO:0005515=PMID:11463338, GO:0032237=PMID:17905723, GO:0005886=PMID:18160041, GO:0051928=PMID:18160041, GO:0005246=PMID:18160041, GO:0005783=PMID:18160041, GO:0005509=PMID:18166150, GO:0006874=PMID:18160041, GO:0005789=GO_REF:0000039, GO:0015279=PMID:16860747, GO:0016021=GO_REF:0000037} Q9P246 Stromal interaction molecule 2 protein 20130415 {GO:0005515=IPI, GO:0032237=IDA, GO:0005886=IDA, GO:0051928=IMP, GO:0005246=IMP, GO:0005783=IDA, GO:0005509=IDA, GO:0006874=IMP, GO:0005789=IEA, GO:0015279=IDA, GO:0016021=IEA} activation of store-operated calcium channel activity, cellular calcium ion homeostasis, positive regulation of calcium ion transport endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, plasma membrane calcium channel regulator activity, calcium ion binding, protein binding, store-operated calcium channel activity Human UniProtKB:Q13586 STIP1 IntAct UniProtKB {GO:0005515=PMID:20029029, GO:0043234=GO_REF:0000019, GO:0005794=PMID:1569099, GO:0007411=Reactome:REACT_18266, GO:0006950=PMID:1569099, GO:0051087=GO_REF:0000019, GO:0030544=GO_REF:0000019, GO:0005634=PMID:16130169, GO:0008022=GO_REF:0000019} P31948 Stress-induced-phosphoprotein 1 protein 20130415 {GO:0005515=IPI, GO:0043234=IEA, GO:0005794=TAS, GO:0007411=TAS, GO:0006950=TAS, GO:0051087=IEA, GO:0030544=IEA, GO:0005634=TAS, GO:0008022=IEA} axon guidance, response to stress Golgi apparatus, nucleus, protein complex Hsp70 protein binding, chaperone binding, protein C-terminus binding, protein binding Human UniProtKB:P00533 STK10 PINC UniProtKB {GO:0005515=PMID:12639966, GO:0007049=GO_REF:0000037, GO:0046777=PMID:12639966, GO:0005886=PMID:19255442, GO:0004674=PMID:19255442, GO:0006468=PMID:9278426, GO:0042801=PMID:12639966, GO:2000401=PMID:19255442, GO:0005524=GO_REF:0000037, GO:0042803=PMID:18239682, GO:0071593=PMID:10692593} O94804 Serine/threonine-protein kinase 10 protein 20030904 {GO:0005515=IPI, GO:0007049=IEA, GO:0046777=IDA, GO:0005886=IDA, GO:0004674=IDA, GO:0006468=TAS, GO:0042801=TAS, GO:2000401=IMP, GO:0005524=IEA, GO:0042803=IDA, GO:0071593=ISS} cell cycle, lymphocyte aggregation, protein autophosphorylation, protein phosphorylation, regulation of lymphocyte migration plasma membrane ATP binding, polo kinase kinase activity, protein binding, protein homodimerization activity, protein serine/threonine kinase activity Human STK11 GOC UniProtKB {GO:0005515=PMID:19892943, GO:0030308=GO_REF:0000024, GO:0030111=GO_REF:0000019, GO:0007286=GO_REF:0000019, GO:0030010=GO_REF:0000024, GO:0007409=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0001558=GO_REF:0000024, GO:0042802=PMID:20562859, GO:0046777=PMID:11430832, GO:0001894=GO_REF:0000019, GO:0045860=PMID:19892943, GO:0051645=GO_REF:0000019, GO:0016772=GO_REF:0000002, GO:0001944=GO_REF:0000024, GO:0000287=PMID:12805220, GO:0043276=PMID:19622832, GO:0043234=GO_REF:0000019, GO:0072332=PMID:11430832, GO:0042304=Reactome:REACT_1988, GO:0050772=GO_REF:0000019, GO:0060770=GO_REF:0000019, GO:0008286=Reactome:REACT_498, GO:0008285=PMID:17216128, GO:0033993=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0051291=GO_REF:0000019, GO:0051896=GO_REF:0000019, GO:0005829=Reactome:REACT_21345, GO:0005739=PMID:11430832, GO:0002039=PMID:11430832, GO:0005737=PMID:18854309, GO:0010212=GO_REF:0000024, GO:0030275=GO_REF:0000019, GO:0033762=GO_REF:0000019, GO:0007050=Reactome:REACT_21387, GO:0060070=GO_REF:0000019, GO:0030511=PMID:18311138, GO:0045722=GO_REF:0000019, GO:0006914=GO_REF:0000037, GO:0030295=PMID:19892943, GO:0042593=GO_REF:0000024, GO:0005524=PMID:12805220, GO:0006974=GO_REF:0000037, GO:0004672=GO_REF:0000002, GO:0006112=Reactome:REACT_1505, GO:0016020=GO_REF:0000024, GO:0004674=Reactome:REACT_11183, GO:0006468=PMID:12805220} Q15831 Serine/threonine-protein kinase STK11 protein 20130413 {GO:0005515=IPI, GO:0030308=ISS, GO:0030111=IEA, GO:0007286=IEA, GO:0030010=ISS, GO:0007409=IEA, GO:0032403=IEA, GO:0001558=ISS, GO:0042802=IPI, GO:0046777=IDA, GO:0001894=IEA, GO:0045860=IDA, GO:0051645=IEA, GO:0016772=IEA, GO:0001944=ISS, GO:0000287=IDA, GO:0043276=IMP, GO:0043234=IEA, GO:0072332=IDA, GO:0042304=TAS, GO:0050772=IEA, GO:0060770=IEA, GO:0008286=TAS, GO:0008285=IMP, GO:0033993=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0051291=IEA, GO:0051896=IEA, GO:0005829=TAS, GO:0005739=IDA, GO:0002039=IDA, GO:0005737=IDA, GO:0010212=ISS, GO:0030275=IEA, GO:0033762=IEA, GO:0007050=TAS, GO:0060070=IEA, GO:0030511=IMP, GO:0045722=IEA, GO:0006914=IEA, GO:0030295=IDA, GO:0042593=ISS, GO:0005524=IDA, GO:0006974=IEA, GO:0004672=IEA, GO:0006112=TAS, GO:0016020=ISS, GO:0004674=TAS, GO:0006468=IDA} Golgi localization, anoikis, autophagy, axonogenesis, canonical Wnt receptor signaling pathway, cell cycle arrest, energy reserve metabolic process, establishment of cell polarity, glucose homeostasis, insulin receptor signaling pathway, intrinsic apoptotic signaling pathway by p53 class mediator, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of epithelial cell proliferation involved in prostate gland development, positive regulation of axonogenesis, positive regulation of gluconeogenesis, positive regulation of protein kinase activity, positive regulation of transforming growth factor beta receptor signaling pathway, protein autophosphorylation, protein heterooligomerization, protein phosphorylation, regulation of Wnt receptor signaling pathway, regulation of cell growth, regulation of fatty acid biosynthetic process, regulation of protein kinase B signaling cascade, response to DNA damage stimulus, response to glucagon stimulus, response to ionizing radiation, response to lipid, small molecule metabolic process, spermatid development, tissue homeostasis, vasculature development cytoplasm, cytosol, membrane, mitochondrion, nucleus, protein complex ATP binding, LRR domain binding, identical protein binding, magnesium ion binding, p53 binding, protein binding, protein complex binding, protein kinase activator activity, protein kinase activity, protein serine/threonine kinase activity, transferase activity, transferring phosphorus-containing groups Human STK11IP HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0008104=PMID:11741830, GO:0019901=PMID:11741830} Q8N1F8 Serine/threonine-protein kinase 11-interacting protein protein 20110516 {GO:0005737=IDA, GO:0008104=IDA, GO:0019901=IPI} protein localization cytoplasm protein kinase binding Human STK16 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0048471=GO_REF:0000039, GO:0001077=GO_REF:0000019, GO:0046777=PMID:18184589, GO:0004672=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0004674=GO_REF:0000019, GO:0005798=GO_REF:0000019, GO:0071560=GO_REF:0000019, GO:0004715=GO_REF:0000003, GO:0005524=GO_REF:0000037} O75716 Serine/threonine-protein kinase 16 protein 20130415 {GO:0005515=IPI, GO:0048471=IEA, GO:0001077=IEA, GO:0046777=IDA, GO:0004672=IEA, GO:0016020=IEA, GO:0004674=IEA, GO:0005798=IEA, GO:0071560=IEA, GO:0004715=IEA, GO:0005524=IEA} cellular response to transforming growth factor beta stimulus, protein autophosphorylation Golgi-associated vesicle, membrane, perinuclear region of cytoplasm ATP binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, non-membrane spanning protein tyrosine kinase activity, protein binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB:Q6UY14 STK17A UniProtKB UniProtKB {GO:0043065=PMID:21489989, GO:0004674=PMID:9786912, GO:0006915=GO_REF:0000037, GO:0006468=PMID:9786912, GO:0005634=PMID:9786912, GO:2000377=PMID:21489989, GO:0006917=PMID:9786912, GO:0005524=PMID:9786912, GO:0007243=PMID:9786912} Q9UEE5 Serine/threonine-protein kinase 17A protein 20111107 {GO:0043065=IMP, GO:0004674=IDA, GO:0006915=IEA, GO:0006468=IDA, GO:0005634=IDA, GO:2000377=IMP, GO:0006917=IMP, GO:0005524=IDA, GO:0007243=IDA} apoptotic process, induction of apoptosis, intracellular protein kinase cascade, positive regulation of apoptotic process, protein phosphorylation, regulation of reactive oxygen species metabolic process nucleus ATP binding, protein serine/threonine kinase activity Human STK17B UniProtKB UniProtKB {GO:0005793=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0005634=PMID:9786912, GO:0012501=GO_REF:0000019, GO:0006917=PMID:9786912, GO:0015629=GO_REF:0000019, GO:0005524=PMID:9786912, GO:0007243=PMID:9786912, GO:0004672=GO_REF:0000024, GO:0046777=GO_REF:0000024, GO:0004674=PMID:9786912, GO:0006468=PMID:9786912} O94768 Serine/threonine-protein kinase 17B protein 20120611 {GO:0005793=IEA, GO:0005886=IEA, GO:0006915=IEA, GO:0005634=IDA, GO:0012501=IEA, GO:0006917=IMP, GO:0015629=IEA, GO:0005524=IDA, GO:0007243=IDA, GO:0004672=ISS, GO:0046777=ISS, GO:0004674=IDA, GO:0006468=IDA} apoptotic process, induction of apoptosis, intracellular protein kinase cascade, programmed cell death, protein autophosphorylation, protein phosphorylation actin cytoskeleton, endoplasmic reticulum-Golgi intermediate compartment, nucleus, plasma membrane ATP binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB:Q91XS8 STK19 PINC UniProtKB {GO:0004674=GO_REF:0000037, GO:0006468=PMID:9812991, GO:0005634=GO_REF:0000039, GO:0005524=GO_REF:0000037} P49842 Serine/threonine-protein kinase 19 protein 20030904 {GO:0004674=IEA, GO:0006468=TAS, GO:0005634=IEA, GO:0005524=IEA} protein phosphorylation nucleus ATP binding, protein serine/threonine kinase activity Human STK24 IntAct UniProtKB {GO:0005515=PMID:23455922, GO:0030336=PMID:17046825, GO:0008631=PMID:19604147, GO:0006915=Reactome:REACT_578, GO:0005634=PMID:12107159, GO:0006917=PMID:12107159, GO:0005524=GO_REF:0000037, GO:0006921=Reactome:REACT_995, GO:0046872=GO_REF:0000037, GO:0048679=PMID:19855390, GO:0005829=Reactome:REACT_13468, GO:0007165=PMID:9353338, GO:0005737=PMID:12107159, GO:0004672=PMID:9353338, GO:0046777=PMID:17046825, GO:0016020=GO_REF:0000039, GO:0004674=PMID:17046825, GO:0005654=Reactome:REACT_13406, GO:0006468=PMID:19604147} Q9Y6E0 Serine/threonine-protein kinase 24 protein 20130415 {GO:0005515=IPI, GO:0030336=IMP, GO:0008631=IMP, GO:0006915=TAS, GO:0005634=IDA, GO:0006917=IMP, GO:0005524=IEA, GO:0006921=TAS, GO:0046872=IEA, GO:0048679=IMP, GO:0005829=TAS, GO:0007165=TAS, GO:0005737=IDA, GO:0004672=TAS, GO:0046777=IDA, GO:0016020=IEA, GO:0004674=IDA, GO:0005654=TAS, GO:0006468=IDA} apoptotic process, cellular component disassembly involved in execution phase of apoptosis, induction of apoptosis, intrinsic apoptotic signaling pathway in response to oxidative stress, negative regulation of cell migration, protein autophosphorylation, protein phosphorylation, regulation of axon regeneration, signal transduction cytoplasm, cytosol, membrane, nucleoplasm, nucleus ATP binding, metal ion binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB:Q9P2B4 STK25 IntAct UniProtKB {GO:0005515=PMID:23455922, GO:0007165=PMID:8887545, GO:0005794=GO_REF:0000039, GO:0007163=GO_REF:0000019, GO:0004672=PMID:9160885, GO:0004674=GO_REF:0000037, GO:0050772=GO_REF:0000019, GO:0006979=PMID:8887545, GO:0051645=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037} O00506 Serine/threonine-protein kinase 25 protein 20130415 {GO:0005515=IPI, GO:0007165=TAS, GO:0005794=IEA, GO:0007163=IEA, GO:0004672=TAS, GO:0004674=IEA, GO:0050772=IEA, GO:0006979=TAS, GO:0051645=IEA, GO:0005524=IEA, GO:0046872=IEA} Golgi localization, establishment or maintenance of cell polarity, positive regulation of axonogenesis, response to oxidative stress, signal transduction Golgi apparatus ATP binding, metal ion binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB:Q9BUL8 STK3 UniProtKB UniProtKB {GO:0005515=PMID:23455922, GO:0051897=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0071902=PMID:20412773, GO:0046330=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0007243=PMID:8566796, GO:0005829=Reactome:REACT_118858, GO:0005737=PMID:19525978, GO:0046983=GO_REF:0000024, GO:0090090=PMID:20412773, GO:0046621=GO_REF:0000019, GO:0043065=GO_REF:0000024, GO:0000287=PMID:8566796, GO:0060706=GO_REF:0000019, GO:0003157=GO_REF:0000019, GO:0006915=PMID:11278283, GO:0060215=GO_REF:0000019, GO:0035329=PMID:20412773, GO:0007417=GO_REF:0000019, GO:0005524=GO_REF:0000038, GO:0001841=GO_REF:0000019, GO:0007165=PMID:8816758, GO:0004672=GO_REF:0000002, GO:0004674=Reactome:REACT_118858, GO:0006468=PMID:20231902, GO:0043539=PMID:20412773} Q8NBU1 cDNA FLJ90748 fis, clone PLACE1011824, highly similar to Human Ste20-like kinase (MST2) mRNA protein 20130413 {GO:0005515=IPI, GO:0051897=IEA, GO:0008285=IEA, GO:0071902=IDA, GO:0046330=IEA, GO:0005634=IEA, GO:0007243=IDA, GO:0005829=TAS, GO:0005737=IDA, GO:0046983=ISS, GO:0090090=IMP, GO:0046621=IEA, GO:0043065=ISS, GO:0000287=IDA, GO:0060706=IEA, GO:0003157=IEA, GO:0006915=TAS, GO:0060215=IEA, GO:0035329=IDA, GO:0007417=IEA, GO:0005524=IEA, GO:0001841=IEA, GO:0007165=TAS, GO:0004672=IEA, GO:0004674=EXP, GO:0006468=IDA, GO:0043539=IDA} apoptotic process, cell differentiation involved in embryonic placenta development, central nervous system development, endocardium development, hippo signaling cascade, intracellular protein kinase cascade, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cell proliferation, negative regulation of organ growth, neural tube formation, positive regulation of JNK cascade, positive regulation of apoptotic process, positive regulation of protein kinase B signaling cascade, positive regulation of protein serine/threonine kinase activity, primitive hemopoiesis, protein phosphorylation, signal transduction cytoplasm, cytosol, nucleus ATP binding, magnesium ion binding, protein binding, protein dimerization activity, protein kinase activity, protein serine/threonine kinase activator activity, protein serine/threonine kinase activity Human UniProtKB-KW:KW-0067 STK31 UniProtKB UniProtKB {GO:0004674=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q9BXU1 Serine/threonine-protein kinase 31 protein 20130413 {GO:0004674=IEA, GO:0005524=IEA} ATP binding, protein serine/threonine kinase activity Human UniProtKB-KW:KW-0067 STK32B UniProtKB UniProtKB {GO:0004674=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q9NY57 Serine/threonine-protein kinase 32B protein 20130413 {GO:0004674=IEA, GO:0005524=IEA, GO:0046872=IEA} ATP binding, metal ion binding, protein serine/threonine kinase activity Human UniProtKB-KW:KW-0479 STK32C UniProtKB UniProtKB {GO:0004674=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q86UX6 Serine/threonine-protein kinase 32C protein 20130413 {GO:0004674=IEA, GO:0005524=IEA, GO:0046872=IEA} ATP binding, metal ion binding, protein serine/threonine kinase activity Human UniProtKB-KW:KW-0479 STK33 HPA UniProtKB {GO:0048471=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0004672=GO_REF:0000002, GO:0046777=GO_REF:0000024, GO:0004674=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037} Q9BYT3 Serine/threonine-protein kinase 33 protein 20090616 {GO:0048471=IEA, GO:0005737=IDA, GO:0005794=IDA, GO:0004672=IEA, GO:0046777=ISS, GO:0004674=ISS, GO:0005634=IDA, GO:0005524=IEA} protein autophosphorylation Golgi apparatus, cytoplasm, nucleus, perinuclear region of cytoplasm ATP binding, protein kinase activity, protein serine/threonine kinase activity Human STK35 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0005524=GO_REF:0000037} Q8TDR2 Serine/threonine-protein kinase 35 protein 20130413 {GO:0005737=IEA, GO:0004672=IEA, GO:0004674=IEA, GO:0005730=IEA, GO:0005524=IEA} cytoplasm, nucleolus ATP binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB-SubCell:SL-0086 STK36 IntAct UniProtKB {GO:0005515=PMID:10806483, GO:0000287=PMID:10806483, GO:0003351=GO_REF:0000019, GO:0005634=PMID:10806483, GO:0007228=GO_REF:0000024, GO:0009791=GO_REF:0000024, GO:0005524=GO_REF:0000029, GO:0042384=GO_REF:0000024, GO:0045880=GO_REF:0000024, GO:0051090=PMID:10806483, GO:0005737=PMID:10806483, GO:0004672=GO_REF:0000002, GO:0004674=PMID:10806483, GO:0007420=GO_REF:0000019, GO:0006468=PMID:10806483, GO:0008134=PMID:10806483} Q9NRP7 Serine/threonine-protein kinase 36 protein 20130415 {GO:0005515=IPI, GO:0000287=IC, GO:0003351=IEA, GO:0005634=IDA, GO:0007228=ISS, GO:0009791=ISS, GO:0005524=NAS, GO:0042384=ISS, GO:0045880=ISS, GO:0051090=IDA, GO:0005737=IDA, GO:0004672=IEA, GO:0004674=TAS, GO:0007420=IEA, GO:0006468=TAS, GO:0008134=IDA} brain development, cilium assembly, epithelial cilium movement, positive regulation of hh target transcription factor activity, positive regulation of smoothened signaling pathway, post-embryonic development, protein phosphorylation, regulation of sequence-specific DNA binding transcription factor activity cytoplasm, nucleus ATP binding, magnesium ion binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, transcription factor binding Human UniProtKB:Q9UMX1 STK38 HPA UniProtKB {GO:0005515=PMID:22939624, GO:0000287=PMID:12493777, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0031435=PMID:17906693, GO:0005524=PMID:12493777, GO:0007243=PMID:12493777, GO:0043231=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0004674=PMID:12493777, GO:0070688=PMID:19377461, GO:0043407=PMID:17906693, GO:0006468=PMID:12493777, GO:0006464=PMID:7761441} Q15208 Serine/threonine-protein kinase 38 protein 20120912 {GO:0005515=IPI, GO:0000287=IDA, GO:0005886=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0031435=IPI, GO:0005524=IDA, GO:0007243=IDA, GO:0043231=IDA, GO:0005737=IDA, GO:0004674=IDA, GO:0070688=IDA, GO:0043407=IDA, GO:0006468=IDA, GO:0006464=IDA} cellular protein modification process, intracellular protein kinase cascade, negative regulation of MAP kinase activity, protein phosphorylation MLL5-L complex, cytoplasm, intracellular membrane-bounded organelle, nucleolus, nucleus, plasma membrane ATP binding, magnesium ion binding, mitogen-activated protein kinase kinase kinase binding, protein binding, protein serine/threonine kinase activity Human STK38L HPA UniProtKB {GO:0005515=PMID:15197186, GO:0000287=PMID:15067004, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003779=GO_REF:0000037, GO:0015629=GO_REF:0000024, GO:0005524=PMID:15067004, GO:0007243=PMID:15067004, GO:0043231=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0004672=GO_REF:0000002, GO:0004674=PMID:15037617, GO:0051128=GO_REF:0000024, GO:0006468=PMID:15037617} Q9Y2H1 Serine/threonine-protein kinase 38-like protein 20120912 {GO:0005515=IPI, GO:0000287=IDA, GO:0005886=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0003779=IEA, GO:0015629=ISS, GO:0005524=IDA, GO:0007243=IDA, GO:0043231=IDA, GO:0005737=IDA, GO:0004672=IEA, GO:0004674=IDA, GO:0051128=ISS, GO:0006468=IDA} intracellular protein kinase cascade, protein phosphorylation, regulation of cellular component organization actin cytoskeleton, cytoplasm, intracellular membrane-bounded organelle, nucleolus, nucleus, plasma membrane ATP binding, actin binding, magnesium ion binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human STK39 GOC UniProtKB {GO:0023014=PMID:10980603, GO:0019901=GO_REF:0000019, GO:0050727=GO_REF:0000019, GO:0006950=PMID:10980603, GO:0043268=GO_REF:0000019, GO:0005634=PMID:10980603, GO:0005524=GO_REF:0000029, GO:0016323=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0005737=PMID:10980603, GO:0004702=PMID:10980603, GO:0006468=PMID:10980603, GO:0005856=GO_REF:0000019} Q9UEW8 STE20/SPS1-related proline-alanine-rich protein kinase protein 20130413 {GO:0023014=NAS, GO:0019901=IEA, GO:0050727=IEA, GO:0006950=NAS, GO:0043268=IEA, GO:0005634=NAS, GO:0005524=NAS, GO:0016323=IEA, GO:0016324=IEA, GO:0005737=NAS, GO:0004702=NAS, GO:0006468=NAS, GO:0005856=IEA} positive regulation of potassium ion transport, protein phosphorylation, regulation of inflammatory response, response to stress, signal transduction by phosphorylation apical plasma membrane, basolateral plasma membrane, cytoplasm, cytoskeleton, nucleus ATP binding, protein kinase binding, receptor signaling protein serine/threonine kinase activity Human STK4 GOC UniProtKB {GO:0005515=PMID:23455922, GO:0008285=GO_REF:0000019, GO:0071902=PMID:20412773, GO:0005634=GO_REF:0000052, GO:0042803=PMID:11805089, GO:0007243=PMID:8566796, GO:0042802=PMID:22863277, GO:0005829=Reactome:REACT_118842, GO:0005737=GO_REF:0000052, GO:0046777=PMID:11805089, GO:0018105=PMID:16751106, GO:0046983=PMID:8702870, GO:0090090=PMID:20412773, GO:0046621=GO_REF:0000019, GO:0001569=GO_REF:0000019, GO:0000287=PMID:8566796, GO:0043065=PMID:15109305, GO:0060706=GO_REF:0000019, GO:0003157=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0060215=GO_REF:0000019, GO:0006917=PMID:21212262, GO:0035329=PMID:20412773, GO:0007417=GO_REF:0000019, GO:0005524=PMID:8566796, GO:0001841=GO_REF:0000019, GO:0000902=PMID:11805089, GO:0007165=PMID:7665586, GO:0030216=GO_REF:0000019, GO:0004674=Reactome:REACT_118842, GO:0006468=PMID:11805089, GO:0043539=PMID:20412773, GO:0008134=PMID:16751106} Q13043 Serine/threonine-protein kinase 4 protein 20130413 {GO:0005515=IPI, GO:0008285=IEA, GO:0071902=IDA, GO:0005634=IDA, GO:0042803=IDA, GO:0007243=IDA, GO:0042802=IPI, GO:0005829=TAS, GO:0005737=IDA, GO:0046777=IDA, GO:0018105=IDA, GO:0046983=IDA, GO:0090090=IMP, GO:0046621=IEA, GO:0001569=IEA, GO:0000287=IDA, GO:0043065=IDA, GO:0060706=IEA, GO:0003157=IEA, GO:0006915=IEA, GO:0060215=IEA, GO:0006917=IDA, GO:0035329=IDA, GO:0007417=IEA, GO:0005524=IDA, GO:0001841=IEA, GO:0000902=IDA, GO:0007165=TAS, GO:0030216=IEA, GO:0004674=EXP, GO:0006468=IDA, GO:0043539=IDA, GO:0008134=IPI} apoptotic process, cell differentiation involved in embryonic placenta development, cell morphogenesis, central nervous system development, endocardium development, hippo signaling cascade, induction of apoptosis, intracellular protein kinase cascade, keratinocyte differentiation, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cell proliferation, negative regulation of organ growth, neural tube formation, patterning of blood vessels, peptidyl-serine phosphorylation, positive regulation of apoptotic process, positive regulation of protein serine/threonine kinase activity, primitive hemopoiesis, protein autophosphorylation, protein phosphorylation, signal transduction cytoplasm, cytosol, nucleus ATP binding, identical protein binding, magnesium ion binding, protein binding, protein dimerization activity, protein homodimerization activity, protein serine/threonine kinase activator activity, protein serine/threonine kinase activity, transcription factor binding Human STK40 HPA UniProtKB {GO:0005515=PMID:21784977, GO:0005737=GO_REF:0000052, GO:0004674=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037} Q8N2I9 Serine/threonine-protein kinase 40 protein 20080818 {GO:0005515=IPI, GO:0005737=IDA, GO:0004674=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005524=IEA} cytoplasm, nucleolus, nucleus ATP binding, protein binding, protein serine/threonine kinase activity Human STMN1 LIFEdb UniProtKB {GO:0031115=GO_REF:0000019, GO:0005874=GO_REF:0000037, GO:0007409=GO_REF:0000019, GO:0009615=PMID:16548883, GO:0005829=GO_REF:0000019, GO:0005622=GO_REF:0000054, GO:0035556=PMID:2917975, GO:0007165=PMID:8003023, GO:0016020=GO_REF:0000019, GO:0015631=PMID:10675326, GO:0004871=PMID:8003023, GO:0007052=PMID:9271428, GO:0051272=GO_REF:0000019, GO:0007019=PMID:9880330} P16949 Stathmin protein 20100607 {GO:0031115=IEA, GO:0005874=IEA, GO:0007409=IEA, GO:0009615=IEP, GO:0005829=IEA, GO:0005622=IDA, GO:0035556=TAS, GO:0007165=NAS, GO:0016020=IEA, GO:0015631=IDA, GO:0004871=TAS, GO:0007052=IDA, GO:0051272=IEA, GO:0007019=IDA} axonogenesis, intracellular signal transduction, microtubule depolymerization, mitotic spindle organization, negative regulation of microtubule polymerization, positive regulation of cellular component movement, response to virus, signal transduction cytosol, intracellular, membrane, microtubule signal transducer activity, tubulin binding Human STMN2 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0030424=GO_REF:0000039, GO:0031115=PMID:18452648, GO:0048471=PMID:18452648, GO:0031117=PMID:18452648, GO:0005794=GO_REF:0000039, GO:0031110=GO_REF:0000002, GO:0030426=GO_REF:0000039, GO:0016020=GO_REF:0000039, GO:0030182=GO_REF:0000029, GO:0010976=PMID:18452648, GO:0007026=PMID:18452648, GO:0010977=PMID:18452648, GO:0005768=GO_REF:0000039} Q93045 Stathmin-2 protein 20130415 {GO:0005515=IPI, GO:0030424=IEA, GO:0031115=IDA, GO:0048471=IDA, GO:0031117=IDA, GO:0005794=IEA, GO:0031110=IEA, GO:0030426=IEA, GO:0016020=IEA, GO:0030182=NAS, GO:0010976=IDA, GO:0007026=IDA, GO:0010977=IDA, GO:0005768=IEA} negative regulation of microtubule depolymerization, negative regulation of microtubule polymerization, negative regulation of neuron projection development, neuron differentiation, positive regulation of microtubule depolymerization, positive regulation of neuron projection development, regulation of microtubule polymerization or depolymerization Golgi apparatus, axon, endosome, growth cone, membrane, perinuclear region of cytoplasm protein binding Human UniProtKB:Q8IYF3 STMN3 HGNC UniProtKB {GO:0030424=GO_REF:0000039, GO:0005737=GO_REF:0000024, GO:0005794=GO_REF:0000039, GO:0035021=GO_REF:0000024, GO:0032314=GO_REF:0000024, GO:0051493=GO_REF:0000024, GO:0031110=GO_REF:0000002, GO:0019904=GO_REF:0000024, GO:0031122=GO_REF:0000024, GO:0031175=GO_REF:0000024, GO:0007399=PMID:9603203, GO:0030426=GO_REF:0000039} Q9NZ72 Stathmin-3 protein 20071023 {GO:0030424=IEA, GO:0005737=ISS, GO:0005794=IEA, GO:0035021=ISS, GO:0032314=ISS, GO:0051493=ISS, GO:0031110=IEA, GO:0019904=ISS, GO:0031122=ISS, GO:0031175=ISS, GO:0007399=TAS, GO:0030426=IEA} cytoplasmic microtubule organization, negative regulation of Rac protein signal transduction, nervous system development, neuron projection development, regulation of Rac GTPase activity, regulation of cytoskeleton organization, regulation of microtubule polymerization or depolymerization Golgi apparatus, axon, cytoplasm, growth cone protein domain specific binding Human UniProtKB:O70166 STMN4 UniProtKB UniProtKB {GO:0030424=GO_REF:0000039, GO:0005794=GO_REF:0000039, GO:0031110=GO_REF:0000002, GO:0030426=GO_REF:0000039} Q9H169 Stathmin-4 protein 20130413 {GO:0030424=IEA, GO:0005794=IEA, GO:0031110=IEA, GO:0030426=IEA} regulation of microtubule polymerization or depolymerization Golgi apparatus, axon, growth cone Human UniProtKB-SubCell:SL-0288 STOM HPA UniProtKB {GO:0042470=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0016020=GO_REF:0000002, GO:0005887=PMID:1547348, GO:0051260=PMID:9642292, GO:0045121=PMID:12130500, GO:0005856=PMID:1547348} P27105 Erythrocyte band 7 integral membrane protein protein 20080205 {GO:0042470=IEA, GO:0005737=IDA, GO:0016020=IEA, GO:0005887=IDA, GO:0051260=IDA, GO:0045121=IDA, GO:0005856=IDA} protein homooligomerization cytoplasm, cytoskeleton, integral to plasma membrane, melanosome, membrane, membrane raft Human STOML1 IntAct UniProtKB {GO:0005515=PMID:23082202, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0032934=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} Q9UBI4 Stomatin-like protein 1 protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0003674=ND, GO:0032934=IEA, GO:0016020=IEA, GO:0005575=ND, GO:0016021=IEA} biological_process cellular_component, integral to membrane, membrane molecular_function, protein binding, sterol binding Human UniProtKB:Q969H0-4 STOML2 PINC UniProtKB {GO:0005515=PMID:21746876, GO:0050852=PMID:18641330, GO:0005743=PMID:17121834, GO:0015629=PMID:18641330, GO:0010876=GO_REF:0000024, GO:0051259=PMID:17121834, GO:0005758=PMID:17121834, GO:0008180=PMID:18850735, GO:0042101=PMID:18641330, GO:0032623=GO_REF:0000024, GO:0005856=PMID:10713127, GO:0001772=PMID:22623988, GO:1900210=PMID:21746876, GO:0006851=PMID:19944461, GO:0034982=GO_REF:0000024, GO:0005102=PMID:10713127, GO:0006874=PMID:19944461, GO:0090297=PMID:21746876, GO:0035710=GO_REF:0000024, GO:0010918=PMID:17121834, GO:0016020=GO_REF:0000002, GO:0042776=PMID:21746876, GO:1901612=PMID:21746876, GO:0045121=PMID:18641330, GO:1990046=GO_REF:0000024, GO:0007005=PMID:21746876, GO:0019897=PMID:22623988} Q9UJZ1 Stomatin-like protein 2, mitochondrial protein 20030904 {GO:0005515=IPI, GO:0050852=IMP, GO:0005743=IDA, GO:0015629=IDA, GO:0010876=ISS, GO:0051259=IDA, GO:0005758=IDA, GO:0008180=IDA, GO:0042101=IDA, GO:0032623=ISS, GO:0005856=TAS, GO:0001772=IDA, GO:1900210=IMP, GO:0006851=IMP, GO:0034982=ISS, GO:0005102=TAS, GO:0006874=IMP, GO:0090297=IMP, GO:0035710=ISS, GO:0010918=IMP, GO:0016020=IEA, GO:0042776=IMP, GO:1901612=IDA, GO:0045121=IDA, GO:1990046=ISS, GO:0007005=IMP, GO:0019897=IDA} CD4-positive, alpha-beta T cell activation, T cell receptor signaling pathway, cellular calcium ion homeostasis, interleukin-2 production, lipid localization, mitochondrial ATP synthesis coupled proton transport, mitochondrial calcium ion transport, mitochondrial protein processing, mitochondrion organization, positive regulation of cardiolipin metabolic process, positive regulation of mitochondrial DNA replication, positive regulation of mitochondrial membrane potential, protein oligomerization, stress-induced mitochondrial fusion T cell receptor complex, actin cytoskeleton, cytoskeleton, extrinsic to plasma membrane, immunological synapse, membrane, membrane raft, mitochondrial inner membrane, mitochondrial intermembrane space, signalosome cardiolipin binding, protein binding, receptor binding Human STOML3 UniProtKB UniProtKB {GO:0007165=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0045121=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q8TAV4 Stomatin-like protein 3 protein 20130413 {GO:0007165=IEA, GO:0005886=IEA, GO:0045121=IEA, GO:0016021=IEA} signal transduction integral to membrane, membrane raft, plasma membrane Human UniProtKB-SubCell:SL-0039 STON2 HPA UniProtKB {GO:0005515=PMID:11454741, GO:0005737=GO_REF:0000052, GO:0030131=GO_REF:0000002, GO:0030100=PMID:14726597, GO:0005730=GO_REF:0000052, GO:0016192=GO_REF:0000002, GO:0006886=GO_REF:0000002, GO:0006897=GO_REF:0000037} Q8WXE9 Stonin-2 protein 20101115 {GO:0005515=IPI, GO:0005737=IDA, GO:0030131=IEA, GO:0030100=ISS, GO:0005730=IDA, GO:0016192=IEA, GO:0006886=IEA, GO:0006897=IEA} endocytosis, intracellular protein transport, regulation of endocytosis, vesicle-mediated transport clathrin adaptor complex, cytoplasm, nucleolus protein binding Human STOX1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037} Q6ZVD7 Storkhead-box protein 1 protein 20110516 {GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA} cytoplasm, nucleolus, nucleus DNA binding Human STOX2 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0001893=PMID:20643876, GO:0005575=GO_REF:0000015, GO:0009790=PMID:20643876} Q9P2F5 Storkhead-box protein 2 protein 20101117 {GO:0003674=ND, GO:0001893=IEP, GO:0005575=ND, GO:0009790=IEP} embryo development, maternal placenta development cellular_component molecular_function Human STRA13 IntAct UniProtKB {GO:0005515=PMID:22304917, GO:0071821=PMID:20347428, GO:0007067=GO_REF:0000037, GO:0003690=PMID:20347428, GO:0006281=GO_REF:0000037, GO:0000712=PMID:20347428, GO:0031398=PMID:20347428, GO:0000777=GO_REF:0000039, GO:0031297=PMID:20347428, GO:0003677=PMID:20347429, GO:0043240=PMID:20347428, GO:0051301=GO_REF:0000037} A8MT69 Centromere protein X protein 20130415 {GO:0005515=IPI, GO:0071821=IDA, GO:0007067=IEA, GO:0003690=IDA, GO:0006281=IEA, GO:0000712=IMP, GO:0031398=TAS, GO:0000777=IEA, GO:0031297=IMP, GO:0003677=IDA, GO:0043240=IDA, GO:0051301=IEA} DNA repair, cell division, mitosis, positive regulation of protein ubiquitination, replication fork processing, resolution of meiotic recombination intermediates FANCM-MHF complex, Fanconi anaemia nuclear complex, condensed chromosome kinetochore DNA binding, double-stranded DNA binding, protein binding Human UniProtKB:Q8N2Z9 STRA6 Reactome UniProtKB {GO:0007631=PMID:17273977, GO:0060426=PMID:17273977, GO:0007603=Reactome:REACT_160125, GO:0005886=Reactome:REACT_160313, GO:0030325=PMID:17273977, GO:0030324=PMID:17273977, GO:0003184=PMID:17273977, GO:0048844=PMID:17273977, GO:0003281=PMID:17273977, GO:0043583=PMID:17273977, GO:0007507=PMID:17273977, GO:0050905=PMID:17273977, GO:0048589=PMID:17273977, GO:0042573=GO_REF:0000019, GO:0048745=PMID:17273977, GO:0061029=PMID:17273977, GO:0048520=PMID:17273977, GO:0061143=PMID:17273977, GO:0004872=GO_REF:0000002, GO:0007612=PMID:17273977, GO:0097070=PMID:19500772, GO:0060900=PMID:17273977, GO:0001568=PMID:17273977, GO:0048286=PMID:17273977, GO:0001822=PMID:17273977, GO:0051183=GO_REF:0000002, GO:0048566=PMID:17273977, GO:0001523=Reactome:REACT_160156, GO:0048546=PMID:17273977, GO:0043234=GO_REF:0000054, GO:0061156=PMID:17273977, GO:0050890=PMID:17273977, GO:0060325=PMID:17273977, GO:0061205=PMID:17273977, GO:0061038=PMID:17273977, GO:0071939=GO_REF:0000019, GO:0060323=PMID:17273977, GO:0060539=PMID:17273977, GO:0060322=PMID:17273977, GO:0016021=GO_REF:0000037, GO:0042297=PMID:17273977, GO:0030540=PMID:17273977, GO:0043585=PMID:17273977} Q9BX79 Stimulated by retinoic acid gene 6 protein homolog protein 20120817 {GO:0007631=IMP, GO:0060426=IMP, GO:0007603=TAS, GO:0005886=TAS, GO:0030325=IMP, GO:0030324=IMP, GO:0003184=IMP, GO:0048844=IMP, GO:0003281=IMP, GO:0043583=IMP, GO:0007507=IMP, GO:0050905=IMP, GO:0048589=IMP, GO:0042573=IEA, GO:0048745=IMP, GO:0061029=IMP, GO:0048520=IMP, GO:0061143=IMP, GO:0004872=IEA, GO:0007612=IMP, GO:0097070=IMP, GO:0060900=IMP, GO:0001568=IMP, GO:0048286=IMP, GO:0001822=IMP, GO:0051183=IEA, GO:0048566=IMP, GO:0001523=TAS, GO:0048546=IMP, GO:0043234=IDA, GO:0061156=IMP, GO:0050890=IMP, GO:0060325=IMP, GO:0061205=IMP, GO:0061038=IMP, GO:0071939=IEA, GO:0060323=IMP, GO:0060539=IMP, GO:0060322=IMP, GO:0016021=IEA, GO:0042297=IMP, GO:0030540=IMP, GO:0043585=IMP} adrenal gland development, alveolar primary septum development, artery morphogenesis, blood vessel development, cognition, developmental growth, diaphragm development, digestive tract morphogenesis, ductus arteriosus closure, ear development, embryonic camera-type eye formation, embryonic digestive tract development, eyelid development in camera-type eye, face morphogenesis, feeding behavior, female genitalia development, head development, head morphogenesis, heart development, kidney development, learning, lung alveolus development, lung development, lung vasculature development, neuromuscular process, nose morphogenesis, paramesonephric duct development, phototransduction, visible light, positive regulation of behavior, pulmonary artery morphogenesis, pulmonary valve morphogenesis, retinoic acid metabolic process, retinoid metabolic process, smooth muscle tissue development, uterus morphogenesis, ventricular septum development, vitamin A import, vocal learning integral to membrane, plasma membrane, protein complex receptor activity, vitamin transporter activity Human STRADA InterPro UniProtKB {GO:0005515=PMID:20562859, GO:0008286=Reactome:REACT_498, GO:0005634=PMID:12805220, GO:0030295=PMID:19892943, GO:0005524=GO_REF:0000002, GO:0005829=Reactome:REACT_21345, GO:0032147=PMID:12805220, GO:0005737=PMID:12805220, GO:0004672=GO_REF:0000002, GO:0004674=PMID:19892943, GO:0006611=PMID:12805220, GO:0006468=PMID:12805220, GO:0007050=Reactome:REACT_21387, GO:0019900=PMID:19892943} Q86YC8 STRADA protein protein 20130413 {GO:0005515=IPI, GO:0008286=TAS, GO:0005634=IDA, GO:0030295=IDA, GO:0005524=IEA, GO:0005829=TAS, GO:0032147=IDA, GO:0005737=IDA, GO:0004672=IEA, GO:0004674=IDA, GO:0006611=IDA, GO:0006468=IDA, GO:0007050=TAS, GO:0019900=IPI} activation of protein kinase activity, cell cycle arrest, insulin receptor signaling pathway, protein export from nucleus, protein phosphorylation cytoplasm, cytosol, nucleus ATP binding, kinase binding, protein binding, protein kinase activator activity, protein kinase activity, protein serine/threonine kinase activity Human InterPro:IPR000719 STRADB Reactome UniProtKB {GO:0008286=Reactome:REACT_498, GO:0043066=GO_REF:0000019, GO:0007254=GO_REF:0000019, GO:0005634=PMID:14517248, GO:0005524=GO_REF:0000029, GO:0005829=Reactome:REACT_21345, GO:0032147=PMID:14517248, GO:0000902=GO_REF:0000019, GO:0005737=PMID:14517248, GO:0004672=PMID:14517248, GO:0006611=PMID:14517248, GO:0006468=PMID:14517248, GO:0007050=Reactome:REACT_21387, GO:0016772=GO_REF:0000002} Q9C0K7 STE20-related kinase adapter protein beta protein 20130301 {GO:0008286=TAS, GO:0043066=IEA, GO:0007254=IEA, GO:0005634=IDA, GO:0005524=NAS, GO:0005829=TAS, GO:0032147=IDA, GO:0000902=IEA, GO:0005737=IDA, GO:0004672=IDA, GO:0006611=IDA, GO:0006468=IDA, GO:0007050=TAS, GO:0016772=IEA} JNK cascade, activation of protein kinase activity, cell cycle arrest, cell morphogenesis, insulin receptor signaling pathway, negative regulation of apoptotic process, protein export from nucleus, protein phosphorylation cytoplasm, cytosol, nucleus ATP binding, protein kinase activity, transferase activity, transferring phosphorus-containing groups Human STRAP HPA UniProtKB {GO:0006397=GO_REF:0000037, GO:0008380=GO_REF:0000037, GO:0030054=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005102=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0000122=GO_REF:0000019, GO:0005829=Reactome:REACT_121338, GO:0005739=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0016301=GO_REF:0000038, GO:0007179=Reactome:REACT_120850, GO:0005681=GO_REF:0000037, GO:0030512=Reactome:REACT_120727} Q9Y3F4 Serine-threonine kinase receptor-associated protein protein 20101115 {GO:0006397=IEA, GO:0008380=IEA, GO:0030054=IDA, GO:0005886=IDA, GO:0005102=IEA, GO:0005634=IDA, GO:0000122=IEA, GO:0005829=TAS, GO:0005739=IDA, GO:0005737=IDA, GO:0016301=IEA, GO:0007179=TAS, GO:0005681=IEA, GO:0030512=TAS} RNA splicing, mRNA processing, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transforming growth factor beta receptor signaling pathway, transforming growth factor beta receptor signaling pathway cell junction, cytoplasm, cytosol, mitochondrion, nucleus, plasma membrane, spliceosomal complex kinase activity, receptor binding Human STRBP LIFEdb UniProtKB {GO:0003725=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0003727=GO_REF:0000019, GO:0015630=GO_REF:0000019, GO:0007286=GO_REF:0000019, GO:0006928=GO_REF:0000019, GO:0005634=GO_REF:0000054, GO:0007275=GO_REF:0000037, GO:0007638=GO_REF:0000019, GO:0003677=GO_REF:0000037} Q96SI9 Spermatid perinuclear RNA-binding protein protein 20100607 {GO:0003725=IEA, GO:0005737=IEA, GO:0003727=IEA, GO:0015630=IEA, GO:0007286=IEA, GO:0006928=IEA, GO:0005634=IDA, GO:0007275=IEA, GO:0007638=IEA, GO:0003677=IEA} cellular component movement, mechanosensory behavior, multicellular organismal development, spermatid development cytoplasm, microtubule cytoskeleton, nucleus DNA binding, double-stranded RNA binding, single-stranded RNA binding Human STRN IntAct UniProtKB {GO:0005515=PMID:23455922, GO:0005516=GO_REF:0000024, GO:0008285=PMID:18502210, GO:0030331=PMID:15569929, GO:0014069=GO_REF:0000024, GO:0000159=PMID:18782753, GO:0032403=PMID:18782753, GO:0016358=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0070830=PMID:18502210, GO:0016020=GO_REF:0000024, GO:0043197=GO_REF:0000024, GO:0045211=GO_REF:0000024, GO:0043025=GO_REF:0000024, GO:0007626=GO_REF:0000024, GO:0005923=PMID:18502210, GO:0016055=PMID:18502210, GO:0051721=PMID:18782753, GO:0070016=PMID:18502210} O43815 Striatin protein 20130415 {GO:0005515=IPI, GO:0005516=ISS, GO:0008285=IMP, GO:0030331=IPI, GO:0014069=ISS, GO:0000159=IDA, GO:0032403=IDA, GO:0016358=ISS, GO:0005737=IEA, GO:0070830=NAS, GO:0016020=ISS, GO:0043197=ISS, GO:0045211=ISS, GO:0043025=ISS, GO:0007626=ISS, GO:0005923=IDA, GO:0016055=IMP, GO:0051721=IDA, GO:0070016=IPI} Wnt receptor signaling pathway, dendrite development, locomotory behavior, negative regulation of cell proliferation, tight junction assembly cytoplasm, dendritic spine, membrane, neuronal cell body, postsynaptic density, postsynaptic membrane, protein phosphatase type 2A complex, tight junction armadillo repeat domain binding, calmodulin binding, estrogen receptor binding, protein binding, protein complex binding, protein phosphatase 2A binding Human UniProtKB:Q9Y6E0 STRN3 IntAct UniProtKB {GO:0005515=PMID:18782753, GO:0005516=PMID:10748158, GO:0005794=PMID:11251078, GO:0005886=PMID:11251078, GO:0000159=PMID:18782753, GO:0032403=PMID:18782753, GO:0030425=GO_REF:0000024, GO:0043234=GO_REF:0000024, GO:0005737=GO_REF:0000019, GO:0043025=GO_REF:0000024, GO:0005654=PMID:11570823, GO:0033147=GO_REF:0000024, GO:0045892=GO_REF:0000019, GO:0051721=PMID:18782753, GO:0032355=GO_REF:0000024, GO:0070016=PMID:18502210} Q13033 Striatin-3 protein 20130415 {GO:0005515=IPI, GO:0005516=NAS, GO:0005794=IDA, GO:0005886=IDA, GO:0000159=IDA, GO:0032403=IDA, GO:0030425=ISS, GO:0043234=ISS, GO:0005737=IEA, GO:0043025=ISS, GO:0005654=IDA, GO:0033147=ISS, GO:0045892=IEA, GO:0051721=IDA, GO:0032355=ISS, GO:0070016=IPI} negative regulation of intracellular estrogen receptor signaling pathway, negative regulation of transcription, DNA-dependent, response to estradiol stimulus Golgi apparatus, cytoplasm, dendrite, neuronal cell body, nucleoplasm, plasma membrane, protein complex, protein phosphatase type 2A complex armadillo repeat domain binding, calmodulin binding, protein binding, protein complex binding, protein phosphatase 2A binding Human UniProtKB:Q9Y228 STRN4 IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0008150=GO_REF:0000015, GO:0005516=PMID:10748158, GO:0043234=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0016020=GO_REF:0000039, GO:0043197=GO_REF:0000039, GO:0019904=GO_REF:0000019, GO:0000159=PMID:18782753, GO:0051721=PMID:18782753, GO:0032403=PMID:18782753, GO:0070016=PMID:18502210} Q9NRL3 Striatin-4 protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0005516=NAS, GO:0043234=IEA, GO:0005737=IEA, GO:0016020=IEA, GO:0043197=IEA, GO:0019904=IEA, GO:0000159=IDA, GO:0051721=IDA, GO:0032403=IDA, GO:0070016=IPI} biological_process cytoplasm, dendritic spine, membrane, protein complex, protein phosphatase type 2A complex armadillo repeat domain binding, calmodulin binding, protein binding, protein complex binding, protein domain specific binding, protein phosphatase 2A binding Human UniProtKB:P05412 STS Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0006706=PMID:6957717, GO:0007565=GO_REF:0000037, GO:0005794=PMID:2668275, GO:0006687=Reactome:REACT_116105, GO:0005886=PMID:2668275, GO:0005783=PMID:2668275, GO:0044281=Reactome:REACT_111217, GO:0008484=PMID:15962010, GO:0005764=PMID:2668275, GO:0046872=GO_REF:0000037, GO:0043231=PMID:6957717, GO:0016020=PMID:2668275, GO:0008544=PMID:9252398, GO:0005789=Reactome:REACT_115686, GO:0005788=Reactome:REACT_121125, GO:0004773=Reactome:REACT_115686, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0005768=PMID:2668275} P08842 Steryl-sulfatase protein 20110928 {GO:0006665=TAS, GO:0006706=TAS, GO:0007565=IEA, GO:0005794=TAS, GO:0006687=TAS, GO:0005886=TAS, GO:0005783=TAS, GO:0044281=TAS, GO:0008484=IDA, GO:0005764=TAS, GO:0046872=IEA, GO:0043231=TAS, GO:0016020=TAS, GO:0008544=TAS, GO:0005789=TAS, GO:0005788=TAS, GO:0004773=TAS, GO:0016021=IEA, GO:0044267=TAS, GO:0043687=TAS, GO:0005768=TAS} cellular protein metabolic process, epidermis development, female pregnancy, glycosphingolipid metabolic process, post-translational protein modification, small molecule metabolic process, sphingolipid metabolic process, steroid catabolic process Golgi apparatus, endoplasmic reticulum, endoplasmic reticulum lumen, endoplasmic reticulum membrane, endosome, integral to membrane, intracellular membrane-bounded organelle, lysosome, membrane, plasma membrane metal ion binding, steryl-sulfatase activity, sulfuric ester hydrolase activity Human STT3A IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0004576=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0005789=Reactome:REACT_22208, GO:0043686=PMID:19167329, GO:0004579=PMID:19167329, GO:0006486=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0008250=PMID:19167329, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} P46977 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A protein 20130415 {GO:0005515=IPI, GO:0004576=IEA, GO:0016020=IEA, GO:0005789=TAS, GO:0043686=IMP, GO:0004579=IMP, GO:0006486=IEA, GO:0016021=IEA, GO:0008250=TAS, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS} cellular protein metabolic process, co-translational protein modification, post-translational protein modification, protein N-linked glycosylation via asparagine, protein glycosylation endoplasmic reticulum membrane, integral to membrane, membrane, oligosaccharyltransferase complex dolichyl-diphosphooligosaccharide-protein glycotransferase activity, oligosaccharyl transferase activity, protein binding Human UniProtKB:Q86WV6 STT3B HPA UniProtKB {GO:0006986=PMID:22607976, GO:0005783=GO_REF:0000052, GO:0043686=PMID:19167329, GO:0004579=PMID:22607976, GO:0006516=PMID:22607976, GO:0016021=GO_REF:0000037, GO:0030433=PMID:22607976, GO:0008250=PMID:22607976, GO:0043687=PMID:22607976, GO:0018279=PMID:22607976} Q8TCJ2 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B protein 20111111 {GO:0006986=IMP, GO:0005783=IDA, GO:0043686=IMP, GO:0004579=IMP, GO:0006516=IMP, GO:0016021=IEA, GO:0030433=IMP, GO:0008250=TAS, GO:0043687=IMP, GO:0018279=IMP} ER-associated protein catabolic process, co-translational protein modification, glycoprotein catabolic process, post-translational protein modification, protein N-linked glycosylation via asparagine, response to unfolded protein endoplasmic reticulum, integral to membrane, oligosaccharyltransferase complex dolichyl-diphosphooligosaccharide-protein glycotransferase activity Human STUB1 BHF-UCL UniProtKB {GO:0005515=PMID:22190034, GO:0006511=PMID:19713937, GO:0004842=Reactome:REACT_120732, GO:0034450=GO_REF:0000024, GO:0051879=PMID:11146632, GO:0032436=PMID:11146632, GO:0000151=PMID:16307917, GO:0046332=PMID:15781469, GO:0042803=GO_REF:0000024, GO:0005829=Reactome:REACT_120732, GO:0051787=PMID:16831871, GO:0051604=PMID:16307917, GO:0070534=PMID:16307917, GO:0005737=PMID:16831871, GO:0090035=PMID:16831871, GO:0031398=PMID:16831871, GO:0007179=Reactome:REACT_120850, GO:0019900=PMID:17512523, GO:0030579=PMID:15781469, GO:0030674=PMID:16307917, GO:0071218=PMID:16831871, GO:0030512=Reactome:REACT_120727, GO:0031625=GO_REF:0000019, GO:0000209=PMID:15781469, GO:0031371=PMID:16307917, GO:0030911=PMID:11146632, GO:0051865=PMID:16307917, GO:0006281=GO_REF:0000037, GO:0030544=PMID:10330192, GO:0006515=PMID:16831871, GO:0043161=PMID:15781469, GO:0019899=PMID:16280320, GO:0031943=PMID:11146632, GO:0042405=PMID:16831871} Q9UNE7 E3 ubiquitin-protein ligase CHIP protein 20091216 {GO:0005515=IPI, GO:0006511=IMP, GO:0004842=TAS, GO:0034450=ISS, GO:0051879=IDA, GO:0032436=IDA, GO:0000151=IDA, GO:0046332=IDA, GO:0042803=ISS, GO:0005829=TAS, GO:0051787=IDA, GO:0051604=TAS, GO:0070534=IDA, GO:0005737=IDA, GO:0090035=IDA, GO:0031398=IDA, GO:0007179=TAS, GO:0019900=IPI, GO:0030579=IDA, GO:0030674=TAS, GO:0071218=IDA, GO:0030512=TAS, GO:0031625=IEA, GO:0000209=IDA, GO:0031371=TAS, GO:0030911=IDA, GO:0051865=IDA, GO:0006281=IEA, GO:0030544=IDA, GO:0006515=IDA, GO:0043161=IDA, GO:0019899=IPI, GO:0031943=IDA, GO:0042405=IDA} DNA repair, cellular response to misfolded protein, misfolded or incompletely synthesized protein catabolic process, negative regulation of transforming growth factor beta receptor signaling pathway, positive regulation of chaperone-mediated protein complex assembly, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of protein ubiquitination, proteasomal ubiquitin-dependent protein catabolic process, protein K63-linked ubiquitination, protein autoubiquitination, protein maturation, protein polyubiquitination, regulation of glucocorticoid metabolic process, transforming growth factor beta receptor signaling pathway, ubiquitin-dependent SMAD protein catabolic process, ubiquitin-dependent protein catabolic process cytoplasm, cytosol, nuclear inclusion body, ubiquitin conjugating enzyme complex, ubiquitin ligase complex Hsp70 protein binding, Hsp90 protein binding, SMAD binding, TPR domain binding, enzyme binding, kinase binding, misfolded protein binding, protein binding, protein binding, bridging, protein homodimerization activity, ubiquitin protein ligase binding, ubiquitin-protein ligase activity, ubiquitin-ubiquitin ligase activity Human UniProtKB:P53667 STX10 InterPro UniProtKB {GO:0005484=GO_REF:0000002, GO:0000139=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0042147=PMID:18195106, GO:0048193=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0006886=GO_REF:0000002} Q5U8S2 Syntaxin-10 protein 20130413 {GO:0005484=IEA, GO:0000139=IEA, GO:0016020=IEA, GO:0042147=IDA, GO:0048193=IEA, GO:0016021=IEA, GO:0006886=IEA} Golgi vesicle transport, intracellular protein transport, retrograde transport, endosome to Golgi Golgi membrane, integral to membrane, membrane SNAP receptor activity Human InterPro:IPR015260 STX11 PINC UniProtKB {GO:0005515=PMID:19804848, GO:0005484=GO_REF:0000002, GO:0005794=GO_REF:0000039, GO:0006944=PMID:9553086, GO:0016020=GO_REF:0000039, GO:0016192=GO_REF:0000002, GO:0006886=GO_REF:0000002} O75558 Syntaxin-11 protein 20030904 {GO:0005515=IPI, GO:0005484=IEA, GO:0005794=IEA, GO:0006944=TAS, GO:0016020=IEA, GO:0016192=IEA, GO:0006886=IEA} cellular membrane fusion, intracellular protein transport, vesicle-mediated transport Golgi apparatus, membrane SNAP receptor activity, protein binding Human STX12 BHF-UCL UniProtKB {GO:0005515=PMID:15469992, GO:0033344=PMID:15469992, GO:0050821=PMID:15469992, GO:0031201=PMID:19546860, GO:0006886=GO_REF:0000033, GO:0016079=GO_REF:0000033, GO:0045335=PMID:15469992, GO:0005484=GO_REF:0000033, GO:0016020=GO_REF:0000002, GO:0000139=GO_REF:0000039, GO:0031083=PMID:19546860, GO:0000149=GO_REF:0000033, GO:0045121=PMID:15469992, GO:0016021=GO_REF:0000037, GO:0016192=GO_REF:0000002, GO:0010008=GO_REF:0000039} Q86Y82 Syntaxin-12 protein 20071114 {GO:0005515=IPI, GO:0033344=IDA, GO:0050821=IDA, GO:0031201=IDA, GO:0006886=IBA, GO:0016079=IBA, GO:0045335=IDA, GO:0005484=IBA, GO:0016020=IEA, GO:0000139=IEA, GO:0031083=IDA, GO:0000149=IBA, GO:0045121=IDA, GO:0016021=IEA, GO:0016192=IEA, GO:0010008=IEA} cholesterol efflux, intracellular protein transport, protein stabilization, synaptic vesicle exocytosis, vesicle-mediated transport BLOC-1 complex, Golgi membrane, SNARE complex, endosome membrane, integral to membrane, membrane, membrane raft, phagocytic vesicle SNAP receptor activity, SNARE binding, protein binding Human STX16 HPA UniProtKB {GO:0005515=PMID:18195106, GO:0005794=PMID:9587053, GO:0005730=GO_REF:0000052, GO:0031201=PMID:15215310, GO:0006891=PMID:9464276, GO:0006886=GO_REF:0000002, GO:0043231=GO_REF:0000052, GO:0005484=PMID:15215310, GO:0005737=PMID:9587053, GO:0016020=GO_REF:0000002, GO:0000139=GO_REF:0000039, GO:0042147=PMID:15215310, GO:0016021=GO_REF:0000037, GO:0016192=GO_REF:0000002} Q96NX8 Syntaxin-16 protein 20120912 {GO:0005515=IPI, GO:0005794=TAS, GO:0005730=IDA, GO:0031201=TAS, GO:0006891=TAS, GO:0006886=IEA, GO:0043231=IDA, GO:0005484=IDA, GO:0005737=TAS, GO:0016020=IEA, GO:0000139=IEA, GO:0042147=IDA, GO:0016021=IEA, GO:0016192=IEA} intra-Golgi vesicle-mediated transport, intracellular protein transport, retrograde transport, endosome to Golgi, vesicle-mediated transport Golgi apparatus, Golgi membrane, SNARE complex, cytoplasm, integral to membrane, intracellular membrane-bounded organelle, membrane, nucleolus SNAP receptor activity, protein binding Human STX17 UniProtKB UniProtKB {GO:0000046=PMID:23217709, GO:0005783=GO_REF:0000019, GO:0000421=PMID:23217709, GO:0031201=PMID:23217709, GO:0006887=GO_REF:0000033, GO:0006886=GO_REF:0000033, GO:0005484=GO_REF:0000033, GO:0016020=GO_REF:0000002, GO:0033116=GO_REF:0000039, GO:0000149=GO_REF:0000033, GO:0005789=PMID:23217709, GO:0016021=GO_REF:0000037, GO:0016192=GO_REF:0000002} P56962 Syntaxin-17 protein 20130412 {GO:0000046=IMP, GO:0005783=IEA, GO:0000421=IDA, GO:0031201=IDA, GO:0006887=IBA, GO:0006886=IBA, GO:0005484=IBA, GO:0016020=IEA, GO:0033116=IEA, GO:0000149=IBA, GO:0005789=IDA, GO:0016021=IEA, GO:0016192=IEA} autophagic vacuole fusion, exocytosis, intracellular protein transport, vesicle-mediated transport SNARE complex, autophagic vacuole membrane, endoplasmic reticulum, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment membrane, integral to membrane, membrane SNAP receptor activity, SNARE binding Human STX18 HGNC UniProtKB {GO:0006888=PMID:10788491, GO:0005515=PMID:15272311, GO:0005484=GO_REF:0000002, GO:0000139=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0005783=PMID:10788491, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0006886=GO_REF:0000002} Q9P2W9 Syntaxin-18 protein 20060522 {GO:0006888=TAS, GO:0005515=IPI, GO:0005484=IEA, GO:0000139=IEA, GO:0016020=IEA, GO:0005783=TAS, GO:0005789=IEA, GO:0016021=IEA, GO:0006886=IEA} ER to Golgi vesicle-mediated transport, intracellular protein transport Golgi membrane, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, membrane SNAP receptor activity, protein binding Human UniProtKB:Q12981 STX1A Reactome UniProtKB {GO:0005515=PMID:10321247, GO:0043005=PMID:12115694, GO:0043008=GO_REF:0000019, GO:0016081=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_23973, GO:0042641=GO_REF:0000019, GO:0031201=PMID:19546860, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0006886=GO_REF:0000002, GO:0007269=Reactome:REACT_13723, GO:0045921=GO_REF:0000019, GO:0001948=GO_REF:0000019, GO:0017156=GO_REF:0000019, GO:0000149=GO_REF:0000019, GO:0030672=GO_REF:0000039, GO:0016192=GO_REF:0000002, GO:0030141=GO_REF:0000019, GO:0030674=GO_REF:0000019, GO:0032028=GO_REF:0000019, GO:0070044=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0014047=Reactome:REACT_12591, GO:0005484=GO_REF:0000002, GO:0006112=Reactome:REACT_1505, GO:0047485=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0009629=GO_REF:0000019, GO:0050796=Reactome:REACT_18325, GO:0019855=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0001956=GO_REF:0000019, GO:0070032=GO_REF:0000019, GO:0044267=Reactome:REACT_17015, GO:0048306=GO_REF:0000019} Q16623 Syntaxin-1A protein 20091203 {GO:0005515=IPI, GO:0043005=IDA, GO:0043008=IEA, GO:0016081=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0042641=IEA, GO:0031201=IDA, GO:0007268=TAS, GO:0044281=TAS, GO:0006886=IEA, GO:0007269=TAS, GO:0045921=IEA, GO:0001948=IEA, GO:0017156=IEA, GO:0000149=IEA, GO:0030672=IEA, GO:0016192=IEA, GO:0030141=IEA, GO:0030674=IEA, GO:0032028=IEA, GO:0070044=IEA, GO:0046982=IEA, GO:0019904=IEA, GO:0005576=IEA, GO:0014047=TAS, GO:0005484=IEA, GO:0006112=TAS, GO:0047485=IEA, GO:0016020=IEA, GO:0009629=IEA, GO:0050796=TAS, GO:0019855=IEA, GO:0016021=IEA, GO:0001956=IEA, GO:0070032=IEA, GO:0044267=TAS, GO:0048306=IEA} calcium ion-dependent exocytosis, cellular protein metabolic process, energy reserve metabolic process, glutamate secretion, intracellular protein transport, neurotransmitter secretion, positive regulation of exocytosis, positive regulation of neurotransmitter secretion, regulation of insulin secretion, response to gravity, small molecule metabolic process, synaptic transmission, synaptic vesicle docking involved in exocytosis, vesicle-mediated transport SNARE complex, actomyosin, cell junction, extracellular region, integral to membrane, membrane, neuron projection, plasma membrane, secretory granule, synaptic vesicle membrane, synaptobrevin 2-SNAP-25-syntaxin-1a complex, synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex ATP-dependent protein binding, SNAP receptor activity, SNARE binding, calcium channel inhibitor activity, calcium-dependent protein binding, glycoprotein binding, myosin head/neck binding, protein N-terminus binding, protein binding, protein binding, bridging, protein domain specific binding, protein heterodimerization activity Human STX1B InterPro UniProtKB {GO:0005484=GO_REF:0000002, GO:0005230=PMID:8105537, GO:0016020=GO_REF:0000002, GO:0005887=PMID:8105537, GO:0005234=PMID:8105537, GO:0019904=GO_REF:0000019, GO:0017157=GO_REF:0000019, GO:0006810=PMID:8105537, GO:0006836=GO_REF:0000037, GO:0007268=GO_REF:0000002, GO:0016192=GO_REF:0000002, GO:0006886=GO_REF:0000002} Q2VPS2 Syntaxin 1B alternative isoform deltaTM protein 20130413 {GO:0005484=IEA, GO:0005230=TAS, GO:0016020=IEA, GO:0005887=TAS, GO:0005234=TAS, GO:0019904=IEA, GO:0017157=IEA, GO:0006810=TAS, GO:0006836=IEA, GO:0007268=IEA, GO:0016192=IEA, GO:0006886=IEA} intracellular protein transport, neurotransmitter transport, regulation of exocytosis, synaptic transmission, transport, vesicle-mediated transport integral to plasma membrane, membrane SNAP receptor activity, extracellular ligand-gated ion channel activity, extracellular-glutamate-gated ion channel activity, protein domain specific binding Human InterPro:IPR010989|InterPro:IPR015709 STX2 HGNC UniProtKB {GO:0005515=PMID:12773094, GO:0009986=GO_REF:0000019, GO:0031410=GO_REF:0000019, GO:0007398=PMID:8466509, GO:0006886=GO_REF:0000002, GO:0030154=GO_REF:0000019, GO:0043231=PMID:8466509, GO:0016323=PMID:16339081, GO:0005484=GO_REF:0000002, GO:0007165=PMID:1581962, GO:0016020=GO_REF:0000002, GO:0005911=GO_REF:0000019, GO:0009887=PMID:1581962, GO:0045121=GO_REF:0000019, GO:0007340=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0016192=GO_REF:0000002, GO:0048306=GO_REF:0000024} P32856 Syntaxin-2 protein 20071018 {GO:0005515=IPI, GO:0009986=IEA, GO:0031410=IEA, GO:0007398=TAS, GO:0006886=IEA, GO:0030154=IEA, GO:0043231=TAS, GO:0016323=IDA, GO:0005484=IEA, GO:0007165=TAS, GO:0016020=IEA, GO:0005911=IEA, GO:0009887=TAS, GO:0045121=IEA, GO:0007340=ISS, GO:0016021=IEA, GO:0016192=IEA, GO:0048306=ISS} acrosome reaction, cell differentiation, ectoderm development, intracellular protein transport, organ morphogenesis, signal transduction, vesicle-mediated transport basolateral plasma membrane, cell surface, cell-cell junction, cytoplasmic vesicle, integral to membrane, intracellular membrane-bounded organelle, membrane, membrane raft SNAP receptor activity, calcium-dependent protein binding, protein binding Human STX3 BHF-UCL UniProtKB {GO:0005773=PMID:16339081, GO:0005515=PMID:18588921, GO:0043005=GO_REF:0000024, GO:0050544=GO_REF:0000024, GO:0042581=PMID:18588921, GO:0042582=PMID:18588921, GO:0031201=GO_REF:0000024, GO:0006887=GO_REF:0000019, GO:0006886=GO_REF:0000002, GO:0031175=GO_REF:0000024, GO:0030426=GO_REF:0000024, GO:0005484=GO_REF:0000002, GO:0016324=PMID:16339081, GO:0016020=GO_REF:0000002, GO:0006944=GO_REF:0000019, GO:0005911=PMID:15576373, GO:0006836=GO_REF:0000037, GO:0034599=PMID:16551573, GO:0016021=GO_REF:0000037, GO:0016192=GO_REF:0000002, GO:0030141=GO_REF:0000019} Q13277 Syntaxin-3 protein 20091104 {GO:0005773=TAS, GO:0005515=IPI, GO:0043005=ISS, GO:0050544=ISS, GO:0042581=IDA, GO:0042582=IDA, GO:0031201=ISS, GO:0006887=IEA, GO:0006886=IEA, GO:0031175=ISS, GO:0030426=ISS, GO:0005484=IEA, GO:0016324=IDA, GO:0016020=IEA, GO:0006944=IEA, GO:0005911=IDA, GO:0006836=IEA, GO:0034599=IDA, GO:0016021=IEA, GO:0016192=IEA, GO:0030141=IEA} cellular membrane fusion, cellular response to oxidative stress, exocytosis, intracellular protein transport, neuron projection development, neurotransmitter transport, vesicle-mediated transport SNARE complex, apical plasma membrane, azurophil granule, cell-cell junction, growth cone, integral to membrane, membrane, neuron projection, secretory granule, specific granule, vacuole SNAP receptor activity, arachidonic acid binding, protein binding Human STX4 HPA UniProtKB {GO:0005773=PMID:16339081, GO:0005515=PMID:16189514, GO:0005802=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0009986=PMID:15576373, GO:0006892=Reactome:REACT_11235, GO:0042581=PMID:18588921, GO:0030168=Reactome:REACT_798, GO:0031201=PMID:19546860, GO:0006886=GO_REF:0000002, GO:0005829=Reactome:REACT_1045, GO:0035749=GO_REF:0000019, GO:0016323=PMID:16339081, GO:0005484=GO_REF:0000002, GO:0016020=PMID:7690687, GO:0007596=Reactome:REACT_604, GO:0000149=GO_REF:0000019, GO:0043219=GO_REF:0000019, GO:0006836=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0016192=GO_REF:0000002, GO:0016044=Reactome:REACT_11123} Q12846 Syntaxin-4 protein 20080205 {GO:0005773=TAS, GO:0005515=IPI, GO:0005802=IEA, GO:0048471=IEA, GO:0005886=IDA, GO:0009986=IDA, GO:0006892=TAS, GO:0042581=IDA, GO:0030168=TAS, GO:0031201=IDA, GO:0006886=IEA, GO:0005829=TAS, GO:0035749=IEA, GO:0016323=IDA, GO:0005484=IEA, GO:0016020=TAS, GO:0007596=TAS, GO:0000149=IEA, GO:0043219=IEA, GO:0006836=IEA, GO:0016021=IEA, GO:0016192=IEA, GO:0016044=TAS} blood coagulation, cellular membrane organization, intracellular protein transport, neurotransmitter transport, platelet activation, post-Golgi vesicle-mediated transport, vesicle-mediated transport SNARE complex, basolateral plasma membrane, cell surface, cytosol, integral to membrane, lateral loop, membrane, myelin sheath adaxonal region, perinuclear region of cytoplasm, plasma membrane, specific granule, trans-Golgi network, vacuole SNAP receptor activity, SNARE binding, protein binding Human STX5 HPA UniProtKB {GO:0005794=GO_REF:0000052, GO:0005783=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0031201=PMID:15215310, GO:0048280=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0006886=GO_REF:0000002, GO:0006903=PMID:9188044, GO:0006888=GO_REF:0000019, GO:0005484=PMID:15215310, GO:0047485=PMID:19536132, GO:0000139=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0033116=GO_REF:0000039, GO:0042147=PMID:15215310, GO:0016021=GO_REF:0000037, GO:0016192=GO_REF:0000002} Q13190 Syntaxin-5 protein 20080205 {GO:0005794=IDA, GO:0005783=IEA, GO:0005730=IDA, GO:0031201=TAS, GO:0048280=IEA, GO:0005634=IDA, GO:0006886=IEA, GO:0006903=TAS, GO:0006888=IEA, GO:0005484=IDA, GO:0047485=IPI, GO:0000139=IEA, GO:0016020=IEA, GO:0033116=IEA, GO:0042147=IDA, GO:0016021=IEA, GO:0016192=IEA} ER to Golgi vesicle-mediated transport, intracellular protein transport, retrograde transport, endosome to Golgi, vesicle fusion with Golgi apparatus, vesicle targeting, vesicle-mediated transport Golgi apparatus, Golgi membrane, SNARE complex, endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment membrane, integral to membrane, membrane, nucleolus, nucleus SNAP receptor activity, protein N-terminus binding Human STX6 BHF-UCL UniProtKB {GO:0005515=PMID:20685960, GO:0048471=PMID:10506127, GO:0005794=PMID:19224922, GO:0005886=PMID:9697774, GO:0030136=PMID:9697774, GO:0031201=PMID:19620288, GO:0006906=PMID:10506127, GO:0006886=GO_REF:0000002, GO:0032588=GO_REF:0000024, GO:0005484=GO_REF:0000002, GO:0000139=GO_REF:0000039, GO:0042147=PMID:19224922, GO:0007032=GO_REF:0000019, GO:0048193=GO_REF:0000002, GO:0016021=GO_REF:0000019, GO:0016192=GO_REF:0000019, GO:0005769=PMID:10506127} O43752 Syntaxin-6 protein 20110308 {GO:0005515=IPI, GO:0048471=IDA, GO:0005794=IDA, GO:0005886=TAS, GO:0030136=TAS, GO:0031201=IDA, GO:0006906=IPI, GO:0006886=IEA, GO:0032588=ISS, GO:0005484=IEA, GO:0000139=IEA, GO:0042147=IMP, GO:0007032=IEA, GO:0048193=IEA, GO:0016021=IEA, GO:0016192=IEA, GO:0005769=IDA} Golgi vesicle transport, endosome organization, intracellular protein transport, retrograde transport, endosome to Golgi, vesicle fusion, vesicle-mediated transport Golgi apparatus, Golgi membrane, SNARE complex, clathrin-coated vesicle, early endosome, integral to membrane, perinuclear region of cytoplasm, plasma membrane, trans-Golgi network membrane SNAP receptor activity, protein binding Human UniProtKB:Q63635 STX7 PINC UniProtKB {GO:0005484=GO_REF:0000033, GO:0048471=GO_REF:0000019, GO:0031901=GO_REF:0000039, GO:0000149=GO_REF:0000033, GO:0006892=PMID:9358037, GO:0031201=GO_REF:0000033, GO:0016021=GO_REF:0000037, GO:0016079=GO_REF:0000033, GO:0006886=GO_REF:0000033} O15400 Syntaxin-7 protein 20030904 {GO:0005484=IBA, GO:0048471=IEA, GO:0031901=IEA, GO:0000149=IBA, GO:0006892=TAS, GO:0031201=IBA, GO:0016021=IEA, GO:0016079=IBA, GO:0006886=IBA} intracellular protein transport, post-Golgi vesicle-mediated transport, synaptic vesicle exocytosis SNARE complex, early endosome membrane, integral to membrane, perinuclear region of cytoplasm SNAP receptor activity, SNARE binding Human STX8 PINC UniProtKB {GO:0005783=PMID:9852078, GO:0005887=PMID:10198254, GO:0031902=GO_REF:0000019, GO:0008333=GO_REF:0000019, GO:0006810=PMID:10198254, GO:0031201=GO_REF:0000019, GO:0005765=GO_REF:0000019, GO:0006906=GO_REF:0000019, GO:0031625=GO_REF:0000019} Q9UNK0 Syntaxin-8 protein 20030904 {GO:0005783=TAS, GO:0005887=TAS, GO:0031902=IEA, GO:0008333=IEA, GO:0006810=TAS, GO:0031201=IEA, GO:0005765=IEA, GO:0006906=IEA, GO:0031625=IEA} endosome to lysosome transport, transport, vesicle fusion SNARE complex, endoplasmic reticulum, integral to plasma membrane, late endosome membrane, lysosomal membrane ubiquitin protein ligase binding Human STXBP1 Reactome UniProtKB {GO:0005886=GO_REF:0000024, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0060292=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0007269=Reactome:REACT_13723, GO:0005829=Reactome:REACT_23973, GO:0006904=GO_REF:0000019, GO:0042802=GO_REF:0000024, GO:0005739=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0007412=GO_REF:0000024, GO:0043524=GO_REF:0000019, GO:0000149=GO_REF:0000024, GO:0031091=PMID:12773094, GO:0017075=GO_REF:0000024, GO:0019905=PMID:12773094, GO:0019901=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0050821=GO_REF:0000019, GO:0010807=GO_REF:0000024, GO:0007274=GO_REF:0000019, GO:0014047=Reactome:REACT_12591, GO:0070527=PMID:12773094, GO:0043234=GO_REF:0000024, GO:0006112=Reactome:REACT_1505, GO:0047485=GO_REF:0000019, GO:0050796=Reactome:REACT_18325, GO:0045956=GO_REF:0000019, GO:0002576=PMID:12773094, GO:0016188=GO_REF:0000024, GO:0032229=GO_REF:0000024} P61764 Syntaxin-binding protein 1 protein 20130114 {GO:0005886=ISS, GO:0007268=TAS, GO:0044281=TAS, GO:0060292=IEA, GO:0015031=IEA, GO:0007269=TAS, GO:0005829=TAS, GO:0006904=IEA, GO:0042802=ISS, GO:0005739=ISS, GO:0005737=ISS, GO:0007412=ISS, GO:0043524=IEA, GO:0000149=ISS, GO:0031091=IDA, GO:0017075=ISS, GO:0019905=IPI, GO:0019901=IEA, GO:0019904=IEA, GO:0050821=IEA, GO:0010807=ISS, GO:0007274=IEA, GO:0014047=TAS, GO:0070527=IMP, GO:0043234=ISS, GO:0006112=TAS, GO:0047485=IEA, GO:0050796=TAS, GO:0045956=IEA, GO:0002576=IMP, GO:0016188=ISS, GO:0032229=ISS} axon target recognition, energy reserve metabolic process, glutamate secretion, long term synaptic depression, negative regulation of neuron apoptotic process, negative regulation of synaptic transmission, GABAergic, neuromuscular synaptic transmission, neurotransmitter secretion, platelet aggregation, platelet degranulation, positive regulation of calcium ion-dependent exocytosis, protein stabilization, protein transport, regulation of insulin secretion, regulation of synaptic vesicle priming, small molecule metabolic process, synaptic transmission, synaptic vesicle maturation, vesicle docking involved in exocytosis cytoplasm, cytosol, mitochondrion, plasma membrane, platelet alpha granule, protein complex SNARE binding, identical protein binding, protein N-terminus binding, protein domain specific binding, protein kinase binding, syntaxin binding, syntaxin-1 binding Human STXBP2 UniProtKB UniProtKB {GO:0005515=PMID:19884660, GO:0043304=GO_REF:0000024, GO:0005886=PMID:18588921, GO:0043312=PMID:18588921, GO:0042581=PMID:18588921, GO:0042582=PMID:18588921, GO:0031201=PMID:12773094, GO:0015031=GO_REF:0000037, GO:0006904=GO_REF:0000002, GO:0030348=PMID:18588921, GO:0005829=PMID:18588921, GO:0001909=PMID:19884660, GO:0016324=GO_REF:0000019, GO:0044194=PMID:19804848, GO:0070820=PMID:18588921, GO:0017075=GO_REF:0000019} Q15833 Syntaxin-binding protein 2 protein 20110622 {GO:0005515=IPI, GO:0043304=ISS, GO:0005886=IDA, GO:0043312=IEP, GO:0042581=IDA, GO:0042582=IDA, GO:0031201=IDA, GO:0015031=IEA, GO:0006904=IEA, GO:0030348=IPI, GO:0005829=IDA, GO:0001909=IMP, GO:0016324=IEA, GO:0044194=IDA, GO:0070820=IDA, GO:0017075=IEA} leukocyte mediated cytotoxicity, neutrophil degranulation, protein transport, regulation of mast cell degranulation, vesicle docking involved in exocytosis SNARE complex, apical plasma membrane, azurophil granule, cytolytic granule, cytosol, plasma membrane, specific granule, tertiary granule protein binding, syntaxin-1 binding, syntaxin-3 binding Human STXBP3 HPA UniProtKB {GO:0019905=PMID:15576373, GO:0005515=PMID:12773094, GO:0005886=PMID:18588921, GO:0043312=PMID:18588921, GO:0005730=GO_REF:0000052, GO:0042581=PMID:18588921, GO:0030168=Reactome:REACT_798, GO:0005634=GO_REF:0000052, GO:0015031=GO_REF:0000037, GO:0051291=GO_REF:0000019, GO:0005829=Reactome:REACT_133, GO:0006904=GO_REF:0000002, GO:0070527=PMID:12773094, GO:0016323=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0016324=GO_REF:0000019, GO:0045955=PMID:12649283, GO:0007596=Reactome:REACT_604, GO:0031091=PMID:12773094, GO:0070820=PMID:18588921, GO:0017075=GO_REF:0000019, GO:0016044=Reactome:REACT_11123} O00186 Syntaxin-binding protein 3 protein 20101115 {GO:0019905=IPI, GO:0005515=IPI, GO:0005886=IDA, GO:0043312=IEP, GO:0005730=IDA, GO:0042581=IDA, GO:0030168=TAS, GO:0005634=IDA, GO:0015031=IEA, GO:0051291=IEA, GO:0005829=TAS, GO:0006904=IEA, GO:0070527=IMP, GO:0016323=IEA, GO:0005737=IDA, GO:0016324=IEA, GO:0045955=IMP, GO:0007596=TAS, GO:0031091=IDA, GO:0070820=IDA, GO:0017075=IEA, GO:0016044=TAS} blood coagulation, cellular membrane organization, negative regulation of calcium ion-dependent exocytosis, neutrophil degranulation, platelet activation, platelet aggregation, protein heterooligomerization, protein transport, vesicle docking involved in exocytosis apical plasma membrane, basolateral plasma membrane, cytoplasm, cytosol, nucleolus, nucleus, plasma membrane, platelet alpha granule, specific granule, tertiary granule protein binding, syntaxin binding, syntaxin-1 binding Human STXBP4 HPA UniProtKB {GO:0008286=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0015758=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006605=GO_REF:0000019, GO:0045111=GO_REF:0000052} Q6ZWJ1 Syntaxin-binding protein 4 protein 20100326 {GO:0008286=IEA, GO:0005737=IDA, GO:0015758=IEA, GO:0005509=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006605=IEA, GO:0045111=IDA} glucose transport, insulin receptor signaling pathway, protein targeting cytoplasm, intermediate filament cytoskeleton, nucleolus, nucleus calcium ion binding Human STXBP5 BHF-UCL UniProtKB {GO:0045921=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0017075=GO_REF:0000024, GO:0016021=GO_REF:0000002, GO:0006887=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0016192=GO_REF:0000002, GO:0005892=GO_REF:0000024, GO:0030659=GO_REF:0000039, GO:0008021=GO_REF:0000039} Q5T5C0 Syntaxin-binding protein 5 protein 20110401 {GO:0045921=ISS, GO:0030054=IEA, GO:0017075=ISS, GO:0016021=IEA, GO:0006887=IEA, GO:0015031=IEA, GO:0016192=IEA, GO:0005892=ISS, GO:0030659=IEA, GO:0008021=IEA} exocytosis, positive regulation of exocytosis, protein transport, vesicle-mediated transport acetylcholine-gated channel complex, cell junction, cytoplasmic vesicle membrane, integral to membrane, synaptic vesicle syntaxin-1 binding Human UniProtKB:Q8K400 STXBP6 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0016021=GO_REF:0000002, GO:0016192=GO_REF:0000002} Q8NFX7 Syntaxin-binding protein 6 protein 20130413 {GO:0005737=IEA, GO:0016021=IEA, GO:0016192=IEA} vesicle-mediated transport cytoplasm, integral to membrane Human UniProtKB-SubCell:SL-0086 STYK1 LIFEdb UniProtKB {GO:0004672=GO_REF:0000002, GO:0005886=GO_REF:0000054, GO:0016021=GO_REF:0000037, GO:0004715=GO_REF:0000003, GO:0005524=GO_REF:0000037} Q6J9G0 Tyrosine-protein kinase STYK1 protein 20100607 {GO:0004672=IEA, GO:0005886=IDA, GO:0016021=IEA, GO:0004715=IEA, GO:0005524=IEA} integral to membrane, plasma membrane ATP binding, non-membrane spanning protein tyrosine kinase activity, protein kinase activity Human STYX RefGenome UniProtKB {GO:0005737=GO_REF:0000033, GO:0006470=GO_REF:0000033, GO:0008138=GO_REF:0000033, GO:0007283=GO_REF:0000033} Q8WUJ0 Serine/threonine/tyrosine-interacting protein protein 20110117 {GO:0005737=IBA, GO:0006470=IKR, GO:0008138=IKR, GO:0007283=IBA} protein dephosphorylation, spermatogenesis cytoplasm protein tyrosine/serine/threonine phosphatase activity NOT Human PANTHER:PTN000017376 STYXL1 PINC UniProtKB {GO:0035556=PMID:9757831, GO:0006470=GO_REF:0000033, GO:0008138=GO_REF:0000033} Q9Y6J8 Serine/threonine/tyrosine-interacting-like protein 1 protein 20030904 {GO:0035556=TAS, GO:0006470=IKR, GO:0008138=IKR} intracellular signal transduction, protein dephosphorylation protein tyrosine/serine/threonine phosphatase activity Human SUB1 HPA UniProtKB {GO:0005515=PMID:11389848, GO:0005667=PMID:8062391, GO:0003697=PMID:8062391, GO:0006357=PMID:8062391, GO:0003713=PMID:8062391, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037} P53999 Activated RNA polymerase II transcriptional coactivator p15 protein 20080205 {GO:0005515=IPI, GO:0005667=IDA, GO:0003697=IDA, GO:0006357=IDA, GO:0003713=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0006351=IEA} regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleolus, nucleus, transcription factor complex protein binding, single-stranded DNA binding, transcription coactivator activity Human SUCLA2 Reactome UniProtKB {GO:0005515=PMID:10727444, GO:0005739=PMID:10727444, GO:0006099=Reactome:REACT_1785, GO:0006105=GO_REF:0000019, GO:0005759=Reactome:REACT_629, GO:0006104=PMID:9765291, GO:0044281=Reactome:REACT_111217, GO:0004775=PMID:10727444, GO:0003824=GO_REF:0000002, GO:0006781=PMID:10727444, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000002} Q9P2R7 "Succinyl-CoA ligase ""ADP-forming"" subunit beta, mitochondrial" protein 20041207 {GO:0005515=IPI, GO:0005739=IDA, GO:0006099=TAS, GO:0006105=IEA, GO:0005759=TAS, GO:0006104=TAS, GO:0044281=TAS, GO:0004775=TAS, GO:0003824=IEA, GO:0006781=NAS, GO:0005524=IEA, GO:0046872=IEA} small molecule metabolic process, succinate metabolic process, succinyl-CoA metabolic process, succinyl-CoA pathway, tricarboxylic acid cycle mitochondrial matrix, mitochondrion ATP binding, catalytic activity, metal ion binding, protein binding, succinate-CoA ligase (ADP-forming) activity Human SUCLG1 HPA UniProtKB {GO:0048037=GO_REF:0000002, GO:0004776=GO_REF:0000003, GO:0006099=Reactome:REACT_1785, GO:0005886=GO_REF:0000052, GO:0046982=GO_REF:0000019, GO:0003878=GO_REF:0000002, GO:0005743=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0005525=GO_REF:0000037, GO:0005739=GO_REF:0000052, GO:0045244=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0006105=GO_REF:0000019, GO:0006104=GO_REF:0000019, GO:0005759=Reactome:REACT_629, GO:0004775=GO_REF:0000003, GO:0019003=GO_REF:0000019} P53597 "Succinyl-CoA ligase ""ADP/GDP-forming"" subunit alpha, mitochondrial" protein 20110516 {GO:0048037=IEA, GO:0004776=IEA, GO:0006099=TAS, GO:0005886=IDA, GO:0046982=IEA, GO:0003878=IEA, GO:0005743=IEA, GO:0044281=TAS, GO:0005525=IEA, GO:0005739=IDA, GO:0045244=IEA, GO:0005737=IDA, GO:0006105=IEA, GO:0006104=IEA, GO:0005759=TAS, GO:0004775=IEA, GO:0019003=IEA} small molecule metabolic process, succinate metabolic process, succinyl-CoA metabolic process, tricarboxylic acid cycle cytoplasm, mitochondrial inner membrane, mitochondrial matrix, mitochondrion, plasma membrane, succinate-CoA ligase complex (GDP-forming) ATP citrate synthase activity, GDP binding, GTP binding, cofactor binding, protein heterodimerization activity, succinate-CoA ligase (ADP-forming) activity, succinate-CoA ligase (GDP-forming) activity Human SUCLG2 Reactome UniProtKB {GO:0004776=PMID:9765291, GO:0006099=Reactome:REACT_1785, GO:0005759=Reactome:REACT_337, GO:0006104=PMID:9765291, GO:0044281=Reactome:REACT_111217, GO:0005525=GO_REF:0000037, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000002} Q96I99 "Succinyl-CoA ligase ""GDP-forming"" subunit beta, mitochondrial" protein 20041207 {GO:0004776=NAS, GO:0006099=TAS, GO:0005759=TAS, GO:0006104=NAS, GO:0044281=TAS, GO:0005525=IEA, GO:0003824=IEA, GO:0005524=IEA} small molecule metabolic process, succinyl-CoA metabolic process, tricarboxylic acid cycle mitochondrial matrix ATP binding, GTP binding, catalytic activity, succinate-CoA ligase (GDP-forming) activity Human SUDS3 BHF-UCL UniProtKB {GO:0005515=PMID:16919237, GO:0016575=PMID:21239494, GO:0043065=PMID:21239494, GO:0042826=PMID:11909966, GO:0006915=GO_REF:0000037, GO:0005634=PMID:21239494, GO:0000122=PMID:22783022, GO:0006351=GO_REF:0000037, GO:0042803=GO_REF:0000019, GO:0016580=PMID:11909966, GO:0004407=PMID:21239494, GO:0019899=PMID:21239494, GO:0045892=PMID:11909966} Q9H7L9 Sin3 histone deacetylase corepressor complex component SDS3 protein 20121121 {GO:0005515=IPI, GO:0016575=IDA, GO:0043065=IMP, GO:0042826=ISS, GO:0006915=IEA, GO:0005634=IDA, GO:0000122=IMP, GO:0006351=IEA, GO:0042803=IEA, GO:0016580=ISS, GO:0004407=IDA, GO:0019899=IPI, GO:0045892=ISS} apoptotic process, histone deacetylation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of apoptotic process, transcription, DNA-dependent Sin3 complex, nucleus enzyme binding, histone deacetylase activity, histone deacetylase binding, protein binding, protein homodimerization activity Human SUFU HPA UniProtKB {GO:0005515=PMID:22439934, GO:0021513=GO_REF:0000019, GO:0006355=PMID:10564661, GO:0008013=GO_REF:0000019, GO:0019901=PMID:20643644, GO:0003714=PMID:10564661, GO:0005730=GO_REF:0000052, GO:0001843=GO_REF:0000019, GO:0045879=PMID:11001584, GO:0007275=PMID:10564661, GO:0042994=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0000122=PMID:10564661, GO:0001947=GO_REF:0000019, GO:0007165=PMID:10559945, GO:0005929=GO_REF:0000019, GO:0001501=PMID:10559945, GO:0005737=PMID:10564661, GO:0045668=PMID:11001584, GO:0006508=PMID:10564661, GO:0043588=GO_REF:0000019, GO:0004871=PMID:10564661, GO:0008134=PMID:10564661} Q9UMX1 Suppressor of fused homolog protein 20080205 {GO:0005515=IPI, GO:0021513=IEA, GO:0006355=TAS, GO:0008013=IEA, GO:0019901=IPI, GO:0003714=TAS, GO:0005730=IDA, GO:0001843=IEA, GO:0045879=TAS, GO:0007275=TAS, GO:0042994=IEA, GO:0005634=IDA, GO:0000122=IDA, GO:0001947=IEA, GO:0007165=TAS, GO:0005929=IEA, GO:0001501=TAS, GO:0005737=IDA, GO:0045668=TAS, GO:0006508=TAS, GO:0043588=IEA, GO:0004871=TAS, GO:0008134=IDA} cytoplasmic sequestering of transcription factor, heart looping, multicellular organismal development, negative regulation of osteoblast differentiation, negative regulation of smoothened signaling pathway, negative regulation of transcription from RNA polymerase II promoter, neural tube closure, proteolysis, regulation of transcription, DNA-dependent, signal transduction, skeletal system development, skin development, spinal cord dorsal/ventral patterning cilium, cytoplasm, nucleolus, nucleus beta-catenin binding, protein binding, protein kinase binding, signal transducer activity, transcription corepressor activity, transcription factor binding NOT Human SUGP1 HPA UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0006396=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0003723=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005654=Reactome:REACT_1935, GO:0005681=GO_REF:0000037, GO:0005634=GO_REF:0000052} Q8IWZ8 SURP and G-patch domain-containing protein 1 protein 20080205 {GO:0008380=TAS, GO:0010467=TAS, GO:0006396=IEA, GO:0000398=TAS, GO:0003723=IEA, GO:0005730=IDA, GO:0005654=TAS, GO:0005681=IEA, GO:0005634=IDA} RNA processing, RNA splicing, gene expression, mRNA splicing, via spliceosome nucleolus, nucleoplasm, nucleus, spliceosomal complex RNA binding NOT Human SUGP2 UniProtKB UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0006396=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0005634=GO_REF:0000039} Q8IX01 SURP and G-patch domain-containing protein 2 protein 20130413 {GO:0008380=IEA, GO:0006397=IEA, GO:0006396=IEA, GO:0003723=IEA, GO:0005634=IEA} RNA processing, RNA splicing, mRNA processing nucleus RNA binding Human UniProtKB-SubCell:SL-0191 SUGT1 Reactome UniProtKB {GO:0007067=PMID:10445024, GO:0045087=Reactome:REACT_6802, GO:0000776=PMID:10445024, GO:0000151=PMID:10445024, GO:0005634=GO_REF:0000039, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_75877} Q9Y2Z0 Suppressor of G2 allele of SKP1 homolog protein 20100610 {GO:0007067=TAS, GO:0045087=TAS, GO:0000776=TAS, GO:0000151=TAS, GO:0005634=IEA, GO:0035872=TAS, GO:0005829=TAS} innate immune response, mitosis, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway cytosol, kinetochore, nucleus, ubiquitin ligase complex Human SULF1 BHF-UCL UniProtKB {GO:0005886=GO_REF:0000024, GO:0051216=GO_REF:0000024, GO:0005783=PMID:18687675, GO:0048706=GO_REF:0000024, GO:0030177=PMID:19520866, GO:0008449=PMID:18687675, GO:0008484=GO_REF:0000002, GO:0003824=GO_REF:0000002, GO:0005615=PMID:19666466, GO:0032836=GO_REF:0000024, GO:0002063=GO_REF:0000024, GO:0004065=PMID:19520866, GO:0030201=PMID:18687675, GO:0048010=PMID:16778174, GO:0030336=PMID:21266348, GO:0005794=GO_REF:0000024, GO:0005795=GO_REF:0000039, GO:0009986=PMID:18687675, GO:0001822=GO_REF:0000024, GO:0005509=GO_REF:0000002, GO:0035860=GO_REF:0000024, GO:0006915=GO_REF:0000037, GO:0010575=GO_REF:0000024, GO:0060686=GO_REF:0000024, GO:0060384=GO_REF:0000024, GO:0060348=GO_REF:0000024, GO:0040036=PMID:21266348, GO:0003094=GO_REF:0000024, GO:0016525=PMID:16778174, GO:0040037=GO_REF:0000024, GO:0045121=PMID:19520866, GO:0014846=GO_REF:0000024} Q8IWU6 Extracellular sulfatase Sulf-1 protein 20110124 {GO:0005886=ISS, GO:0051216=ISS, GO:0005783=IDA, GO:0048706=ISS, GO:0030177=IDA, GO:0008449=IDA, GO:0008484=IEA, GO:0003824=IEA, GO:0005615=IDA, GO:0032836=ISS, GO:0002063=ISS, GO:0004065=IMP, GO:0030201=IDA, GO:0048010=IDA, GO:0030336=IMP, GO:0005794=ISS, GO:0005795=IEA, GO:0009986=IDA, GO:0001822=ISS, GO:0005509=IEA, GO:0035860=ISS, GO:0006915=IEA, GO:0010575=ISS, GO:0060686=ISS, GO:0060384=ISS, GO:0060348=ISS, GO:0040036=IMP, GO:0003094=ISS, GO:0016525=IDA, GO:0040037=ISS, GO:0045121=IDA, GO:0014846=ISS} apoptotic process, bone development, cartilage development, chondrocyte development, embryonic skeletal system development, esophagus smooth muscle contraction, glial cell-derived neurotrophic factor receptor signaling pathway, glomerular basement membrane development, glomerular filtration, heparan sulfate proteoglycan metabolic process, innervation, kidney development, negative regulation of angiogenesis, negative regulation of cell migration, negative regulation of fibroblast growth factor receptor signaling pathway, negative regulation of prostatic bud formation, positive regulation of Wnt receptor signaling pathway, positive regulation vascular endothelial growth factor production, regulation of fibroblast growth factor receptor signaling pathway, vascular endothelial growth factor receptor signaling pathway Golgi apparatus, Golgi stack, cell surface, endoplasmic reticulum, extracellular space, membrane raft, plasma membrane N-acetylglucosamine-6-sulfatase activity, arylsulfatase activity, calcium ion binding, catalytic activity, sulfuric ester hydrolase activity Human UniProtKB:Q8K007 SULF2 BHF-UCL UniProtKB {GO:0005794=GO_REF:0000002, GO:0005795=GO_REF:0000039, GO:0009986=PMID:18687675, GO:0005886=GO_REF:0000024, GO:0001822=GO_REF:0000024, GO:0051216=GO_REF:0000024, GO:0005783=PMID:18687675, GO:0005509=GO_REF:0000002, GO:0048706=GO_REF:0000024, GO:0030177=PMID:19520866, GO:0035860=GO_REF:0000024, GO:0008449=PMID:18687675, GO:0008484=GO_REF:0000002, GO:0010575=GO_REF:0000024, GO:0032836=GO_REF:0000024, GO:0005615=PMID:12368295, GO:0060384=GO_REF:0000024, GO:0060348=GO_REF:0000024, GO:0002063=GO_REF:0000024, GO:0003094=GO_REF:0000024, GO:0040037=GO_REF:0000024, GO:0004065=PMID:19520866, GO:0014846=GO_REF:0000024, GO:0030201=PMID:18687675} Q8IWU5 Extracellular sulfatase Sulf-2 protein 20110124 {GO:0005794=IEA, GO:0005795=IEA, GO:0009986=IDA, GO:0005886=ISS, GO:0001822=ISS, GO:0051216=ISS, GO:0005783=IDA, GO:0005509=IEA, GO:0048706=ISS, GO:0030177=IDA, GO:0035860=ISS, GO:0008449=IDA, GO:0008484=IEA, GO:0010575=ISS, GO:0032836=ISS, GO:0005615=NAS, GO:0060384=ISS, GO:0060348=ISS, GO:0002063=ISS, GO:0003094=ISS, GO:0040037=ISS, GO:0004065=IMP, GO:0014846=ISS, GO:0030201=IDA} bone development, cartilage development, chondrocyte development, embryonic skeletal system development, esophagus smooth muscle contraction, glial cell-derived neurotrophic factor receptor signaling pathway, glomerular basement membrane development, glomerular filtration, heparan sulfate proteoglycan metabolic process, innervation, kidney development, negative regulation of fibroblast growth factor receptor signaling pathway, positive regulation of Wnt receptor signaling pathway, positive regulation vascular endothelial growth factor production Golgi apparatus, Golgi stack, cell surface, endoplasmic reticulum, extracellular space, plasma membrane N-acetylglucosamine-6-sulfatase activity, arylsulfatase activity, calcium ion binding, sulfuric ester hydrolase activity Human UniProtKB:Q8CFG0 SULT1A1 BHF-UCL UniProtKB {GO:0050294=PMID:16221673, GO:0047894=PMID:20056724, GO:0006805=PMID:20056724, GO:0050427=Reactome:REACT_6913, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_6961, GO:0008210=PMID:16221673, GO:0009812=PMID:20056724, GO:0006584=GO_REF:0000037, GO:0004062=Reactome:REACT_6897, GO:0008146=PMID:8661000, GO:0051923=PMID:20056724, GO:0009308=PMID:8661000, GO:0016021=GO_REF:0000002} P50225 Sulfotransferase 1A1 protein 20100723 {GO:0050294=IDA, GO:0047894=IDA, GO:0006805=IDA, GO:0050427=TAS, GO:0044281=TAS, GO:0005829=TAS, GO:0008210=IDA, GO:0009812=IDA, GO:0006584=IEA, GO:0004062=TAS, GO:0008146=TAS, GO:0051923=IDA, GO:0009308=TAS, GO:0016021=IEA} 3'-phosphoadenosine 5'-phosphosulfate metabolic process, amine metabolic process, catecholamine metabolic process, estrogen metabolic process, flavonoid metabolic process, small molecule metabolic process, sulfation, xenobiotic metabolic process cytosol, integral to membrane aryl sulfotransferase activity, flavonol 3-sulfotransferase activity, steroid sulfotransferase activity, sulfotransferase activity Human SULT1A2 BHF-UCL UniProtKB {GO:0047894=PMID:20056724, GO:0006805=Reactome:REACT_13433, GO:0050427=Reactome:REACT_6913, GO:0004062=PMID:20417180, GO:0006584=GO_REF:0000037, GO:0008146=PMID:9119390, GO:0051923=PMID:20056724, GO:0044281=Reactome:REACT_111217, GO:0009309=PMID:9119390, GO:0018958=PMID:20417180, GO:0008202=GO_REF:0000037, GO:0005829=Reactome:REACT_6925} P50226 Sulfotransferase 1A2 protein 20100723 {GO:0047894=IDA, GO:0006805=TAS, GO:0050427=TAS, GO:0004062=IDA, GO:0006584=IEA, GO:0008146=TAS, GO:0051923=IDA, GO:0044281=TAS, GO:0009309=TAS, GO:0018958=IDA, GO:0008202=IEA, GO:0005829=TAS} 3'-phosphoadenosine 5'-phosphosulfate metabolic process, amine biosynthetic process, catecholamine metabolic process, phenol-containing compound metabolic process, small molecule metabolic process, steroid metabolic process, sulfation, xenobiotic metabolic process cytosol aryl sulfotransferase activity, flavonol 3-sulfotransferase activity, sulfotransferase activity Human SULT1A3 BHF-UCL UniProtKB {GO:0006805=PMID:20056724, GO:0050427=Reactome:REACT_6913, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_115832, GO:0030968=Reactome:REACT_18356, GO:0005737=PMID:8363592, GO:0009812=PMID:20056724, GO:0006584=GO_REF:0000037, GO:0004062=Reactome:REACT_6740, GO:0008146=PMID:20056724, GO:0051923=PMID:20056724, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0008202=GO_REF:0000037} P50224 Sulfotransferase 1A3/1A4 protein 20100723 {GO:0006805=IDA, GO:0050427=TAS, GO:0044281=TAS, GO:0005829=TAS, GO:0030968=TAS, GO:0005737=TAS, GO:0009812=IDA, GO:0006584=IEA, GO:0004062=TAS, GO:0008146=IDA, GO:0051923=IDA, GO:0006987=TAS, GO:0044267=TAS, GO:0008202=IEA} 3'-phosphoadenosine 5'-phosphosulfate metabolic process, activation of signaling protein activity involved in unfolded protein response, catecholamine metabolic process, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, flavonoid metabolic process, small molecule metabolic process, steroid metabolic process, sulfation, xenobiotic metabolic process cytoplasm, cytosol aryl sulfotransferase activity, sulfotransferase activity Human SULT1A4 InterPro UniProtKB {GO:0008146=GO_REF:0000002} H3BNY7 Sulfotransferase 1A3/1A4 protein 20130413 {GO:0008146=IEA} sulfotransferase activity Human InterPro:IPR000863 SULT1B1 BHF-UCL UniProtKB {GO:0042403=PMID:9443824, GO:0006805=PMID:20056724, GO:0009812=PMID:20056724, GO:0050427=Reactome:REACT_6913, GO:0004062=GO_REF:0000019, GO:0008146=PMID:20056724, GO:0051923=PMID:20056724, GO:0044281=Reactome:REACT_111217, GO:0018958=PMID:9463486, GO:0008202=GO_REF:0000037, GO:0006576=PMID:9443824, GO:0005829=Reactome:REACT_6961} O43704 Sulfotransferase family cytosolic 1B member 1 protein 20100723 {GO:0042403=IDA, GO:0006805=IDA, GO:0009812=IDA, GO:0050427=TAS, GO:0004062=IEA, GO:0008146=IDA, GO:0051923=IDA, GO:0044281=TAS, GO:0018958=IDA, GO:0008202=IEA, GO:0006576=TAS, GO:0005829=TAS} 3'-phosphoadenosine 5'-phosphosulfate metabolic process, cellular biogenic amine metabolic process, flavonoid metabolic process, phenol-containing compound metabolic process, small molecule metabolic process, steroid metabolic process, sulfation, thyroid hormone metabolic process, xenobiotic metabolic process cytosol aryl sulfotransferase activity, sulfotransferase activity Human SULT1C2 BHF-UCL UniProtKB {GO:0005737=PMID:9169148, GO:0006805=Reactome:REACT_13433, GO:0050427=Reactome:REACT_6913, GO:0015630=GO_REF:0000052, GO:0008146=PMID:20056724, GO:0051923=PMID:20056724, GO:0009308=PMID:9169148, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_6961} O00338 Sulfotransferase 1C2 protein 20100723 {GO:0005737=TAS, GO:0006805=TAS, GO:0050427=TAS, GO:0015630=IDA, GO:0008146=IDA, GO:0051923=IDA, GO:0009308=TAS, GO:0044281=TAS, GO:0005829=TAS} 3'-phosphoadenosine 5'-phosphosulfate metabolic process, amine metabolic process, small molecule metabolic process, sulfation, xenobiotic metabolic process cytoplasm, cytosol, microtubule cytoskeleton sulfotransferase activity Human SULT1C4 InterPro UniProtKB {GO:0006805=Reactome:REACT_13433, GO:0050427=Reactome:REACT_6913, GO:0008146=GO_REF:0000002, GO:0051923=PMID:20056724, GO:0044281=Reactome:REACT_111217, GO:0005575=GO_REF:0000015, GO:0005829=Reactome:REACT_6925} Q08AS5 cDNA FLJ53816, highly similar to Sulfotransferase 1C2 (EC 2.8.2.-) protein 20130413 {GO:0006805=TAS, GO:0050427=TAS, GO:0008146=IEA, GO:0051923=IDA, GO:0044281=TAS, GO:0005575=ND, GO:0005829=TAS} 3'-phosphoadenosine 5'-phosphosulfate metabolic process, small molecule metabolic process, sulfation, xenobiotic metabolic process cellular_component, cytosol sulfotransferase activity Human InterPro:IPR000863 SULT1E1 BHF-UCL UniProtKB {GO:0050294=Reactome:REACT_6949, GO:0047894=PMID:20056724, GO:0031965=GO_REF:0000052, GO:0007565=GO_REF:0000019, GO:0004304=GO_REF:0000003, GO:0006805=Reactome:REACT_13433, GO:0050427=Reactome:REACT_6913, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_6969, GO:0008210=PMID:11884392, GO:0005737=GO_REF:0000052, GO:0008146=GO_REF:0000002, GO:0051923=PMID:20056724, GO:0005496=GO_REF:0000037, GO:0008202=PMID:8185618} P49888 Estrogen sulfotransferase protein 20100723 {GO:0050294=TAS, GO:0047894=IDA, GO:0031965=IDA, GO:0007565=IEA, GO:0004304=IEA, GO:0006805=TAS, GO:0050427=TAS, GO:0005634=IDA, GO:0044281=TAS, GO:0005829=TAS, GO:0008210=IDA, GO:0005737=IDA, GO:0008146=IEA, GO:0051923=IDA, GO:0005496=IEA, GO:0008202=TAS} 3'-phosphoadenosine 5'-phosphosulfate metabolic process, estrogen metabolic process, female pregnancy, small molecule metabolic process, steroid metabolic process, sulfation, xenobiotic metabolic process cytoplasm, cytosol, nuclear membrane, nucleus estrone sulfotransferase activity, flavonol 3-sulfotransferase activity, steroid binding, steroid sulfotransferase activity, sulfotransferase activity Human SULT2A1 BHF-UCL UniProtKB {GO:0005515=PMID:21988832, GO:0006805=Reactome:REACT_13433, GO:0050427=Reactome:REACT_6913, GO:0030573=GO_REF:0000037, GO:0007586=PMID:1588921, GO:0008146=PMID:20056724, GO:0051923=PMID:20056724, GO:0044281=Reactome:REACT_111217, GO:0047704=GO_REF:0000003, GO:0044255=Reactome:REACT_22279, GO:0008202=PMID:1588921, GO:0005829=Reactome:REACT_115729} Q06520 Bile salt sulfotransferase protein 20100723 {GO:0005515=IPI, GO:0006805=TAS, GO:0050427=TAS, GO:0030573=IEA, GO:0007586=NAS, GO:0008146=IDA, GO:0051923=IDA, GO:0044281=TAS, GO:0047704=IEA, GO:0044255=TAS, GO:0008202=TAS, GO:0005829=TAS} 3'-phosphoadenosine 5'-phosphosulfate metabolic process, bile acid catabolic process, cellular lipid metabolic process, digestion, small molecule metabolic process, steroid metabolic process, sulfation, xenobiotic metabolic process cytosol bile-salt sulfotransferase activity, protein binding, sulfotransferase activity Human SULT2B1 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0050294=PMID:12145317, GO:0005737=PMID:9799594, GO:0006805=Reactome:REACT_13433, GO:0050427=Reactome:REACT_6913, GO:0004027=Reactome:REACT_6957, GO:0005783=GO_REF:0000037, GO:0000103=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0008202=PMID:12145317, GO:0005829=Reactome:REACT_6969} O00204 Sulfotransferase family cytosolic 2B member 1 protein 20130415 {GO:0005515=IPI, GO:0050294=IDA, GO:0005737=TAS, GO:0006805=TAS, GO:0050427=TAS, GO:0004027=TAS, GO:0005783=IEA, GO:0000103=IEA, GO:0005634=IEA, GO:0044281=TAS, GO:0008202=IDA, GO:0005829=TAS} 3'-phosphoadenosine 5'-phosphosulfate metabolic process, small molecule metabolic process, steroid metabolic process, sulfate assimilation, xenobiotic metabolic process cytoplasm, cytosol, endoplasmic reticulum, nucleus alcohol sulfotransferase activity, protein binding, steroid sulfotransferase activity Human UniProtKB:Q96Q35 SULT4A1 Reactome UniProtKB {GO:0008150=GO_REF:0000015, GO:0006805=Reactome:REACT_13433, GO:0050427=Reactome:REACT_6913, GO:0008146=PMID:10698717, GO:0044281=Reactome:REACT_111217, GO:0008202=GO_REF:0000037, GO:0005829=Reactome:REACT_6961} Q9BR01 Sulfotransferase 4A1 protein 20130213 {GO:0008150=ND, GO:0006805=TAS, GO:0050427=TAS, GO:0008146=NAS, GO:0044281=TAS, GO:0008202=IEA, GO:0005829=TAS} 3'-phosphoadenosine 5'-phosphosulfate metabolic process, biological_process, small molecule metabolic process, steroid metabolic process, xenobiotic metabolic process cytosol sulfotransferase activity Human SUMF1 Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0006687=Reactome:REACT_116105, GO:0016491=GO_REF:0000037, GO:0005788=Reactome:REACT_121184, GO:0044281=Reactome:REACT_111217, GO:0044267=Reactome:REACT_17015, GO:0042803=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0043687=Reactome:REACT_22161} Q8NBK3 Sulfatase-modifying factor 1 protein 20130301 {GO:0006665=TAS, GO:0006687=TAS, GO:0016491=IEA, GO:0005788=TAS, GO:0044281=TAS, GO:0044267=TAS, GO:0042803=IEA, GO:0046872=IEA, GO:0043687=TAS} cellular protein metabolic process, glycosphingolipid metabolic process, post-translational protein modification, small molecule metabolic process, sphingolipid metabolic process endoplasmic reticulum lumen metal ion binding, oxidoreductase activity, protein homodimerization activity Human SUMF2 Reactome UniProtKB {GO:0005783=GO_REF:0000019, GO:0005788=Reactome:REACT_121184, GO:0044267=Reactome:REACT_17015, GO:0046872=GO_REF:0000037, GO:0042803=GO_REF:0000019, GO:0043687=Reactome:REACT_22161} Q8NBJ7 Sulfatase-modifying factor 2 protein 20110928 {GO:0005783=IEA, GO:0005788=TAS, GO:0044267=TAS, GO:0046872=IEA, GO:0042803=IEA, GO:0043687=TAS} cellular protein metabolic process, post-translational protein modification endoplasmic reticulum, endoplasmic reticulum lumen metal ion binding, protein homodimerization activity Human SUMO1 BHF-UCL UniProtKB {GO:0005515=PMID:21242980, GO:0019221=Reactome:REACT_25229, GO:0032436=PMID:18408734, GO:0045202=GO_REF:0000019, GO:0005634=PMID:9412458, GO:0030425=GO_REF:0000019, GO:0043433=PMID:12072434, GO:0060334=Reactome:REACT_24980, GO:0032880=PMID:15637059, GO:0005737=GO_REF:0000039, GO:0031334=PMID:18579533, GO:0090204=GO_REF:0000019, GO:0030578=GO_REF:0000019, GO:0005643=PMID:9019411, GO:0019789=GO_REF:0000019, GO:0060021=GO_REF:0000024, GO:0031625=PMID:18408734, GO:0060333=Reactome:REACT_25078, GO:0031965=GO_REF:0000039, GO:0006355=GO_REF:0000019, GO:0016925=PMID:15637059, GO:0043392=PMID:15637059, GO:0016604=GO_REF:0000019, GO:0006281=PMID:8812453, GO:0016607=GO_REF:0000039, GO:0016605=PMID:9412458, GO:0005654=Reactome:REACT_25331, GO:0045892=PMID:12072434, GO:0008134=GO_REF:0000019} P63165 Small ubiquitin-related modifier 1 protein 20081129 {GO:0005515=IPI, GO:0019221=TAS, GO:0032436=IDA, GO:0045202=IEA, GO:0005634=IDA, GO:0030425=IEA, GO:0043433=IMP, GO:0060334=TAS, GO:0032880=TAS, GO:0005737=IEA, GO:0031334=IDA, GO:0090204=IEA, GO:0030578=IEA, GO:0005643=TAS, GO:0019789=IEA, GO:0060021=ISS, GO:0031625=IPI, GO:0060333=TAS, GO:0031965=IEA, GO:0006355=IEA, GO:0016925=IDA, GO:0043392=IMP, GO:0016604=IEA, GO:0006281=TAS, GO:0016607=IEA, GO:0016605=IDA, GO:0005654=TAS, GO:0045892=IMP, GO:0008134=IEA} DNA repair, PML body organization, cytokine-mediated signaling pathway, interferon-gamma-mediated signaling pathway, negative regulation of DNA binding, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription, DNA-dependent, palate development, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of protein complex assembly, protein localization to nuclear pore, protein sumoylation, regulation of interferon-gamma-mediated signaling pathway, regulation of protein localization, regulation of transcription, DNA-dependent PML body, cytoplasm, dendrite, nuclear body, nuclear membrane, nuclear pore, nuclear speck, nucleoplasm, nucleus, synapse SUMO ligase activity, protein binding, transcription factor binding, ubiquitin protein ligase binding Human SUMO2 IntAct UniProtKB {GO:0005515=PMID:20802522, GO:0016605=PMID:22406621, GO:0016925=PMID:17696781, GO:0032436=PMID:18408734, GO:0005634=GO_REF:0000002, GO:0031625=PMID:18408734} P61956 Small ubiquitin-related modifier 2 protein 20130415 {GO:0005515=IPI, GO:0016605=IDA, GO:0016925=IDA, GO:0032436=IDA, GO:0005634=IEA, GO:0031625=IPI} positive regulation of proteasomal ubiquitin-dependent protein catabolic process, protein sumoylation PML body, nucleus protein binding, ubiquitin protein ligase binding Human UniProtKB:P10242 SUMO3 IntAct UniProtKB {GO:0005515=PMID:17000644, GO:0016604=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:2000060=GO_REF:0000019, GO:0034504=GO_REF:0000019, GO:0019789=GO_REF:0000019, GO:0016925=PMID:17696781, GO:0000776=PMID:9119407, GO:0005634=GO_REF:0000002} P55854 Small ubiquitin-related modifier 3 protein 20130415 {GO:0005515=IPI, GO:0016604=IEA, GO:0005737=IEA, GO:2000060=IEA, GO:0034504=IEA, GO:0019789=IEA, GO:0016925=IDA, GO:0000776=TAS, GO:0005634=IEA} positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process, protein localization to nucleus, protein sumoylation cytoplasm, kinetochore, nuclear body, nucleus SUMO ligase activity, protein binding Human UniProtKB:P23497 SUMO4 ENSEMBL UniProtKB {GO:0045944=GO_REF:0000019, GO:0019789=GO_REF:0000019, GO:0016925=GO_REF:0000019, GO:0005634=GO_REF:0000002} Q6EEV6 Small ubiquitin-related modifier 4 protein 20130413 {GO:0045944=IEA, GO:0019789=IEA, GO:0016925=IEA, GO:0005634=IEA} positive regulation of transcription from RNA polymerase II promoter, protein sumoylation nucleus SUMO ligase activity Human Ensembl:ENSMUSP00000115044 SUN1 HPA UniProtKB {GO:0005515=PMID:22632968, GO:0031965=GO_REF:0000052, GO:0090292=PMID:18396275, GO:0005637=GO_REF:0000039, GO:0034993=PMID:18396275, GO:0090286=PMID:18396275, GO:0005635=PMID:19933576, GO:0005639=GO_REF:0000019, GO:0043231=GO_REF:0000052, GO:0006998=PMID:16380439, GO:0016021=GO_REF:0000037, GO:0002080=GO_REF:0000019, GO:0005521=GO_REF:0000019} O94901 SUN domain-containing protein 1 protein 20080205 {GO:0005515=IPI, GO:0031965=IDA, GO:0090292=IDA, GO:0005637=IEA, GO:0034993=IDA, GO:0090286=IDA, GO:0005635=IDA, GO:0005639=IEA, GO:0043231=IDA, GO:0006998=IGI, GO:0016021=IEA, GO:0002080=IEA, GO:0005521=IEA} cytoskeletal anchoring at nuclear membrane, nuclear envelope organization, nuclear matrix anchoring at nuclear membrane SUN-KASH complex, acrosomal membrane, integral to membrane, integral to nuclear inner membrane, intracellular membrane-bounded organelle, nuclear envelope, nuclear inner membrane, nuclear membrane lamin binding, protein binding Human SUN2 HPA UniProtKB {GO:0005515=PMID:22632968, GO:0008017=PMID:10375507, GO:0031965=GO_REF:0000052, GO:0000794=GO_REF:0000019, GO:0030335=GO_REF:0000024, GO:0007097=PMID:10508607, GO:0090292=PMID:19933576, GO:0005637=GO_REF:0000039, GO:0034993=PMID:18396275, GO:0005635=PMID:16380439, GO:0090286=PMID:18396275, GO:0042802=PMID:22632968, GO:0051642=GO_REF:0000024, GO:0031022=GO_REF:0000024, GO:0006998=PMID:16380439, GO:0016021=GO_REF:0000037, GO:0007052=PMID:10375507, GO:0005521=PMID:19933576, GO:0000784=GO_REF:0000019, GO:0010008=GO_REF:0000039} Q9UH99 SUN domain-containing protein 2 protein 20080205 {GO:0005515=IPI, GO:0008017=TAS, GO:0031965=IDA, GO:0000794=IEA, GO:0030335=ISS, GO:0007097=TAS, GO:0090292=IDA, GO:0005637=IEA, GO:0034993=IDA, GO:0005635=IDA, GO:0090286=IDA, GO:0042802=IPI, GO:0051642=ISS, GO:0031022=ISS, GO:0006998=IGI, GO:0016021=IEA, GO:0007052=TAS, GO:0005521=IDA, GO:0000784=IEA, GO:0010008=IEA} centrosome localization, cytoskeletal anchoring at nuclear membrane, mitotic spindle organization, nuclear envelope organization, nuclear matrix anchoring at nuclear membrane, nuclear migration, nuclear migration along microfilament, positive regulation of cell migration SUN-KASH complex, condensed nuclear chromosome, endosome membrane, integral to membrane, nuclear chromosome, telomeric region, nuclear envelope, nuclear inner membrane, nuclear membrane identical protein binding, lamin binding, microtubule binding, protein binding Human SUN5 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0007283=PMID:12621555} Q8TC36 SUN domain-containing protein 5 protein 20061026 {GO:0003674=ND, GO:0005575=ND, GO:0007283=IEP} spermatogenesis cellular_component molecular_function Human SUOX Reactome UniProtKB {GO:0009055=GO_REF:0000002, GO:0008482=Reactome:REACT_116081, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000038, GO:0005739=GO_REF:0000019, GO:0043546=GO_REF:0000002, GO:0005758=GO_REF:0000039, GO:0034641=Reactome:REACT_13, GO:0000096=Reactome:REACT_115639, GO:0000098=Reactome:REACT_115654, GO:0005759=Reactome:REACT_116081, GO:0070221=Reactome:REACT_116010, GO:0020037=GO_REF:0000002, GO:0030151=GO_REF:0000002} P51687 Sulfite oxidase, mitochondrial protein 20120112 {GO:0009055=IEA, GO:0008482=TAS, GO:0044281=TAS, GO:0046872=IEA, GO:0005739=IEA, GO:0043546=IEA, GO:0005758=IEA, GO:0034641=TAS, GO:0000096=TAS, GO:0000098=TAS, GO:0005759=TAS, GO:0070221=TAS, GO:0020037=IEA, GO:0030151=IEA} cellular nitrogen compound metabolic process, small molecule metabolic process, sulfide oxidation, using sulfide:quinone oxidoreductase, sulfur amino acid catabolic process, sulfur amino acid metabolic process mitochondrial intermembrane space, mitochondrial matrix, mitochondrion electron carrier activity, heme binding, metal ion binding, molybdenum ion binding, molybdopterin cofactor binding, sulfite oxidase activity Human SUPT16H Reactome UniProtKB {GO:0006260=GO_REF:0000037, GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006368=Reactome:REACT_1845, GO:0032786=PMID:10421373, GO:0006281=GO_REF:0000037, GO:0006366=Reactome:REACT_1366, GO:0005694=GO_REF:0000039, GO:0016032=Reactome:REACT_6256, GO:0005654=Reactome:REACT_6355, GO:0006337=PMID:10421373, GO:0050434=Reactome:REACT_6162} Q9Y5B9 FACT complex subunit SPT16 protein 20130213 {GO:0006260=IEA, GO:0022415=TAS, GO:0010467=TAS, GO:0006368=TAS, GO:0032786=TAS, GO:0006281=IEA, GO:0006366=TAS, GO:0005694=IEA, GO:0016032=TAS, GO:0005654=TAS, GO:0006337=TAS, GO:0050434=TAS} DNA repair, DNA replication, gene expression, nucleosome disassembly, positive regulation of DNA-dependent transcription, elongation, positive regulation of viral transcription, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, viral reproduction, viral reproductive process chromosome, nucleoplasm Human SUPT3H HPA UniProtKB {GO:0006352=GO_REF:0000029, GO:0016578=PMID:18206972, GO:0006355=PMID:9787080, GO:0006366=GO_REF:0000002, GO:0046982=GO_REF:0000002, GO:0006357=PMID:9787080, GO:0030914=PMID:11564863, GO:0003713=PMID:11564863, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0033276=PMID:10373431, GO:0043966=PMID:11564863, GO:0045893=PMID:9787080, GO:0004402=PMID:11564863} Q5VWT9 Transcription initiation protein SPT3 homolog protein 20100326 {GO:0006352=NAS, GO:0016578=IDA, GO:0006355=NAS, GO:0006366=IEA, GO:0046982=IEA, GO:0006357=TAS, GO:0030914=IDA, GO:0003713=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0033276=IDA, GO:0043966=IDA, GO:0045893=NAS, GO:0004402=IDA} DNA-dependent transcription, initiation, histone H3 acetylation, histone deubiquitination, positive regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter STAGA complex, nucleolus, nucleus, transcription factor TFTC complex histone acetyltransferase activity, protein heterodimerization activity, transcription coactivator activity NOT Human SUPT4H1 IntAct UniProtKB {GO:0005515=PMID:10075709, GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006368=Reactome:REACT_1845, GO:0006355=PMID:8786137, GO:0032044=PMID:9450929, GO:0003700=PMID:8649394, GO:0006366=Reactome:REACT_1366, GO:0006357=PMID:8649394, GO:0046982=PMID:9450929, GO:0005634=PMID:8649394, GO:0000122=PMID:9450929, GO:0050434=Reactome:REACT_6162, GO:0032786=PMID:9450929, GO:0032785=PMID:9450929, GO:0045944=PMID:9450929, GO:0016032=Reactome:REACT_6256, GO:0006338=PMID:8649394, GO:0005654=Reactome:REACT_6355, GO:0008270=GO_REF:0000002, GO:0034244=GO_REF:0000019} P63272 Transcription elongation factor SPT4 protein 20130415 {GO:0005515=IPI, GO:0022415=TAS, GO:0010467=TAS, GO:0006368=TAS, GO:0006355=TAS, GO:0032044=IDA, GO:0003700=TAS, GO:0006366=TAS, GO:0006357=TAS, GO:0046982=IPI, GO:0005634=IDA, GO:0000122=IDA, GO:0050434=TAS, GO:0032786=IDA, GO:0032785=IDA, GO:0045944=IDA, GO:0016032=TAS, GO:0006338=TAS, GO:0005654=TAS, GO:0008270=IEA, GO:0034244=IEA} chromatin remodeling, gene expression, negative regulation of DNA-dependent transcription, elongation, negative regulation of transcription elongation from RNA polymerase II promoter, negative regulation of transcription from RNA polymerase II promoter, positive regulation of DNA-dependent transcription, elongation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of viral transcription, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, viral reproduction, viral reproductive process DSIF complex, nucleoplasm, nucleus protein binding, protein heterodimerization activity, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB:O00267 SUPT5H BHF-UCL UniProtKB {GO:0005515=PMID:16169070, GO:0010467=Reactome:REACT_71, GO:0022415=Reactome:REACT_6361, GO:0006368=Reactome:REACT_1845, GO:0006366=Reactome:REACT_1366, GO:0005634=GO_REF:0000052, GO:0045090=PMID:10075709, GO:0032786=PMID:9450929, GO:0032785=PMID:10075709, GO:0032784=GO_REF:0000002, GO:0045944=PMID:9450929, GO:0016032=Reactome:REACT_6256, GO:0006338=PMID:10075709, GO:0016239=PMID:22354037, GO:0010033=PMID:10075709, GO:0006354=PMID:10075709, GO:0032044=PMID:9450929, GO:0046982=PMID:9450929, GO:0006357=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0006370=Reactome:REACT_1470, GO:0000122=PMID:10075709, GO:0050434=Reactome:REACT_6162, GO:0007049=PMID:10075709, GO:0032968=GO_REF:0000002, GO:0005654=Reactome:REACT_6355, GO:0019899=PMID:10075709} O00267 Transcription elongation factor SPT5 protein 20120531 {GO:0005515=IPI, GO:0010467=TAS, GO:0022415=TAS, GO:0006368=TAS, GO:0006366=TAS, GO:0005634=IDA, GO:0045090=NAS, GO:0032786=IDA, GO:0032785=IDA, GO:0032784=IEA, GO:0045944=IDA, GO:0016032=TAS, GO:0006338=NAS, GO:0016239=IMP, GO:0010033=TAS, GO:0006354=IDA, GO:0032044=IDA, GO:0046982=IPI, GO:0006357=IEA, GO:0005730=IDA, GO:0006370=TAS, GO:0000122=IDA, GO:0050434=TAS, GO:0007049=NAS, GO:0032968=IEA, GO:0005654=TAS, GO:0019899=IPI} 7-methylguanosine mRNA capping, DNA-dependent transcription, elongation, cell cycle, chromatin remodeling, gene expression, negative regulation of DNA-dependent transcription, elongation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of DNA-dependent transcription, elongation, positive regulation of macroautophagy, positive regulation of transcription elongation from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter, positive regulation of viral transcription, regulation of DNA-dependent transcription, elongation, regulation of transcription from RNA polymerase II promoter, response to organic substance, retroviral genome replication, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, viral reproduction, viral reproductive process DSIF complex, nucleolus, nucleoplasm, nucleus enzyme binding, protein binding, protein heterodimerization activity Human SUPT6H PINC UniProtKB {GO:0006355=PMID:8786132, GO:0003700=PMID:8786132, GO:0006357=GO_REF:0000002, GO:0032784=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0003723=GO_REF:0000002, GO:0016788=GO_REF:0000002, GO:0006338=PMID:8786132, GO:0005634=PMID:8786132, GO:0006351=GO_REF:0000037} Q7KZ85 Transcription elongation factor SPT6 protein 20050308 {GO:0006355=NAS, GO:0003700=TAS, GO:0006357=IEA, GO:0032784=IEA, GO:0019048=IEA, GO:0003723=IEA, GO:0016788=IEA, GO:0006338=NAS, GO:0005634=NAS, GO:0006351=IEA} chromatin remodeling, regulation of DNA-dependent transcription, elongation, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription, DNA-dependent, virus-host interaction nucleus RNA binding, hydrolase activity, acting on ester bonds, sequence-specific DNA binding transcription factor activity Human SUPT7L HGNC UniProtKB {GO:0006355=GO_REF:0000037, GO:0043966=PMID:11564863, GO:0051457=PMID:15870280, GO:0030914=PMID:11564863, GO:0003713=PMID:11564863, GO:0005634=PMID:15870280, GO:0004402=PMID:11564863, GO:0006351=GO_REF:0000037} O94864 STAGA complex 65 subunit gamma protein 20061114 {GO:0006355=IEA, GO:0043966=IDA, GO:0051457=IDA, GO:0030914=IDA, GO:0003713=IDA, GO:0005634=IDA, GO:0004402=IDA, GO:0006351=IEA} histone H3 acetylation, maintenance of protein location in nucleus, regulation of transcription, DNA-dependent, transcription, DNA-dependent STAGA complex, nucleus histone acetyltransferase activity, transcription coactivator activity Human SUPV3L1 BHF-UCL UniProtKB {GO:0042645=PMID:18063578, GO:0005515=PMID:17961633, GO:0003725=PMID:19509288, GO:0000962=PMID:19864255, GO:0000965=PMID:19864255, GO:0030307=PMID:19864255, GO:0003723=PMID:9925937, GO:0035946=PMID:19864255, GO:0035945=PMID:19864255, GO:0005634=PMID:17352692, GO:0042803=PMID:19509288, GO:0005739=PMID:19864255, GO:0004004=PMID:19509288, GO:0005759=PMID:12466530, GO:0032508=PMID:12466530, GO:0043066=PMID:17352692, GO:0070827=PMID:17352692, GO:0004386=PMID:9925937, GO:0006310=PMID:17961633, GO:0000958=PMID:19864255, GO:2000827=PMID:19864255, GO:0003676=GO_REF:0000002, GO:0003677=PMID:12466530, GO:0005524=GO_REF:0000037, GO:0003678=PMID:12466530, GO:0006401=PMID:18678873, GO:0070584=PMID:19864255, GO:0045025=PMID:19509288, GO:0034458=PMID:19509288} Q8IYB8 ATP-dependent RNA helicase SUPV3L1, mitochondrial protein 20090218 {GO:0042645=IDA, GO:0005515=IPI, GO:0003725=IDA, GO:0000962=IMP, GO:0000965=IMP, GO:0030307=IMP, GO:0003723=TAS, GO:0035946=IMP, GO:0035945=IMP, GO:0005634=IDA, GO:0042803=IPI, GO:0005739=IDA, GO:0004004=IDA, GO:0005759=IDA, GO:0032508=IMP, GO:0043066=IMP, GO:0070827=IMP, GO:0004386=TAS, GO:0006310=IMP, GO:0000958=IMP, GO:2000827=IMP, GO:0003676=IEA, GO:0003677=IMP, GO:0005524=IEA, GO:0003678=IMP, GO:0006401=IMP, GO:0070584=IMP, GO:0045025=IDA, GO:0034458=IDA} DNA duplex unwinding, DNA recombination, RNA catabolic process, chromatin maintenance, mitochondrial RNA 3'-end processing, mitochondrial RNA surveillance, mitochondrial mRNA catabolic process, mitochondrial mRNA surveillance, mitochondrial ncRNA surveillance, mitochondrion morphogenesis, negative regulation of apoptotic process, positive regulation of cell growth, positive regulation of mitochondrial RNA catabolic process mitochondrial degradosome, mitochondrial matrix, mitochondrial nucleoid, mitochondrion, nucleus 3'-5' RNA helicase activity, ATP binding, ATP-dependent RNA helicase activity, DNA binding, DNA helicase activity, RNA binding, double-stranded RNA binding, helicase activity, nucleic acid binding, protein binding, protein homodimerization activity Human SURF1 BHF-UCL UniProtKB {GO:0009060=PMID:9843204, GO:0006754=PMID:20888800, GO:0005746=PMID:9843204, GO:0008535=PMID:9843204, GO:0004129=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0006119=PMID:20888800, GO:0055114=PMID:9843204} Q15526 Surfeit locus protein 1 protein 20120716 {GO:0009060=TAS, GO:0006754=IMP, GO:0005746=TAS, GO:0008535=TAS, GO:0004129=IEA, GO:0016021=IEA, GO:0006119=IMP, GO:0055114=TAS} ATP biosynthetic process, aerobic respiration, oxidation-reduction process, oxidative phosphorylation, respiratory chain complex IV assembly integral to membrane, mitochondrial respiratory chain cytochrome-c oxidase activity Human SURF2 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q15527 Surfeit locus protein 2 protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human SURF4 InterPro UniProtKB {GO:0005515=PMID:21903422, GO:0010638=PMID:18287528, GO:0005793=PMID:18287528, GO:0000139=GO_REF:0000039, GO:0034498=PMID:18287528, GO:0033116=GO_REF:0000039, GO:0007030=PMID:18287528, GO:0005789=GO_REF:0000039, GO:0032527=PMID:18287528, GO:0016021=GO_REF:0000002} Q5T8U7 Surfeit locus protein 4 protein 20130413 {GO:0005515=IPI, GO:0010638=IMP, GO:0005793=IDA, GO:0000139=IEA, GO:0034498=IMP, GO:0033116=IEA, GO:0007030=IMP, GO:0005789=IEA, GO:0032527=IMP, GO:0016021=IEA} Golgi organization, early endosome to Golgi transport, positive regulation of organelle organization, protein exit from endoplasmic reticulum Golgi membrane, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment, endoplasmic reticulum-Golgi intermediate compartment membrane, integral to membrane protein binding Human InterPro:IPR002995 SURF6 PINC UniProtKB {GO:0001652=GO_REF:0000024, GO:0003723=GO_REF:0000024, GO:0042254=GO_REF:0000019, GO:0005730=PMID:10675619, GO:0044451=GO_REF:0000019, GO:0003677=GO_REF:0000024} O75683 Surfeit locus protein 6 protein 20030904 {GO:0001652=ISS, GO:0003723=ISS, GO:0042254=IEA, GO:0005730=TAS, GO:0044451=IEA, GO:0003677=ISS} ribosome biogenesis granular component, nucleolus, nucleoplasm part DNA binding, RNA binding Human SUSD1 UniProtKB UniProtKB {GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q6UWL2 Sushi domain-containing protein 1 protein 20130413 {GO:0005509=IEA, GO:0016021=IEA} integral to membrane calcium ion binding Human UniProtKB-KW:KW-0812 SUSD2 UniProtKB UniProtKB {GO:0006955=GO_REF:0000002, GO:0030247=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005044=GO_REF:0000002} Q9UGT4 Sushi domain-containing protein 2 protein 20130413 {GO:0006955=IEA, GO:0030247=IEA, GO:0016021=IEA, GO:0005044=IEA} immune response integral to membrane polysaccharide binding, scavenger receptor activity Human UniProtKB-KW:KW-0812 SUSD3 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q96L08 Sushi domain-containing protein 3 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 SUV39H1 IntAct UniProtKB {GO:0005515=PMID:20562864, GO:0000792=PMID:18004385, GO:0000794=PMID:10202156, GO:0005694=GO_REF:0000038, GO:0006364=GO_REF:0000037, GO:0006325=PMID:10949293, GO:0033553=PMID:18485871, GO:0005634=PMID:18004385, GO:0008757=PMID:10949293, GO:0006351=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0018024=PMID:17707234, GO:0042054=PMID:10949293, GO:0007049=GO_REF:0000037, GO:0047485=PMID:19218236, GO:0000183=PMID:18485871, GO:0003682=PMID:10202156, GO:0019048=GO_REF:0000037, GO:0046974=PMID:18004385, GO:0008270=GO_REF:0000002, GO:0000775=GO_REF:0000039, GO:0005677=PMID:18485871} O43463 Histone-lysine N-methyltransferase SUV39H1 protein 20130415 {GO:0005515=IPI, GO:0000792=IDA, GO:0000794=TAS, GO:0005694=IEA, GO:0006364=IEA, GO:0006325=TAS, GO:0033553=IDA, GO:0005634=IDA, GO:0008757=IDA, GO:0006351=IEA, GO:0030154=IEA, GO:0018024=IDA, GO:0042054=IDA, GO:0007049=IEA, GO:0047485=IPI, GO:0000183=IDA, GO:0003682=TAS, GO:0019048=IEA, GO:0046974=IDA, GO:0008270=IEA, GO:0000775=IEA, GO:0005677=IDA} cell cycle, cell differentiation, chromatin organization, chromatin silencing at rDNA, rRNA processing, transcription, DNA-dependent, virus-host interaction chromatin silencing complex, chromosome, chromosome, centromeric region, condensed nuclear chromosome, heterochromatin, nucleus, rDNA heterochromatin S-adenosylmethionine-dependent methyltransferase activity, chromatin binding, histone methyltransferase activity, histone methyltransferase activity (H3-K9 specific), histone-lysine N-methyltransferase activity, protein N-terminus binding, protein binding, zinc ion binding Human UniProtKB:P45973 SUV39H2 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0006355=GO_REF:0000037, GO:0008168=GO_REF:0000038, GO:0005634=GO_REF:0000038, GO:0006351=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0006333=PMID:10949293, GO:0018024=GO_REF:0000019, GO:0005720=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0046974=PMID:10949293, GO:0006338=PMID:10949293, GO:0008270=GO_REF:0000002, GO:0000785=PMID:10949293, GO:0000775=GO_REF:0000039, GO:0007140=GO_REF:0000019, GO:0051567=GO_REF:0000019} Q9H5I1 Histone-lysine N-methyltransferase SUV39H2 protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0008168=IEA, GO:0005634=IEA, GO:0006351=IEA, GO:0030154=IEA, GO:0006333=IMP, GO:0018024=IEA, GO:0005720=IEA, GO:0003682=IEA, GO:0046974=IDA, GO:0006338=IDA, GO:0008270=IEA, GO:0000785=IDA, GO:0000775=IEA, GO:0007140=IEA, GO:0051567=IEA} cell differentiation, chromatin assembly or disassembly, chromatin remodeling, histone H3-K9 methylation, male meiosis, regulation of transcription, DNA-dependent, transcription, DNA-dependent chromatin, chromosome, centromeric region, nuclear heterochromatin, nucleus chromatin binding, histone methyltransferase activity (H3-K9 specific), histone-lysine N-methyltransferase activity, methyltransferase activity, protein binding, zinc ion binding Human UniProtKB:P16333 SUV420H1 UniProtKB UniProtKB {GO:0000780=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0042799=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0018024=PMID:17707234, GO:0034773=GO_REF:0000002} Q4FZB7 Histone-lysine N-methyltransferase SUV420H1 protein 20110121 {GO:0000780=IEA, GO:0006355=IEA, GO:0042799=IEA, GO:0006351=IEA, GO:0018024=IDA, GO:0034773=IEA} histone H4-K20 trimethylation, regulation of transcription, DNA-dependent, transcription, DNA-dependent condensed nuclear chromosome, centromeric region histone methyltransferase activity (H4-K20 specific), histone-lysine N-methyltransferase activity Human SUV420H2 UniProtKB UniProtKB {GO:0005515=PMID:19486527, GO:0000780=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0042799=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0034773=GO_REF:0000002} Q86Y97 Histone-lysine N-methyltransferase SUV420H2 protein 20090706 {GO:0005515=IPI, GO:0000780=IEA, GO:0006355=IEA, GO:0042799=IEA, GO:0006351=IEA, GO:0034773=IEA} histone H4-K20 trimethylation, regulation of transcription, DNA-dependent, transcription, DNA-dependent condensed nuclear chromosome, centromeric region histone methyltransferase activity (H4-K20 specific), protein binding Human UniProtKB:P83916 SUZ12 IntAct UniProtKB {GO:0005515=PMID:23079660, GO:0008284=GO_REF:0000019, GO:0016574=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0035064=PMID:21029866, GO:0001739=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0042054=PMID:15385962, GO:0043565=GO_REF:0000019, GO:0035098=PMID:15385962, GO:0003682=GO_REF:0000019, GO:0045596=PMID:19847889} Q15022 Polycomb protein SUZ12 protein 20130415 {GO:0005515=IPI, GO:0008284=IEA, GO:0016574=IEA, GO:0000122=IEA, GO:0035064=IDA, GO:0001739=IEA, GO:0006351=IEA, GO:0046872=IEA, GO:0042054=IMP, GO:0043565=IEA, GO:0035098=IMP, GO:0003682=IEA, GO:0045596=IMP} histone ubiquitination, negative regulation of cell differentiation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of cell proliferation, transcription, DNA-dependent ESC/E(Z) complex, sex chromatin chromatin binding, histone methyltransferase activity, metal ion binding, methylated histone residue binding, protein binding, sequence-specific DNA binding Human UniProtKB:O15379 SV2A HPA UniProtKB {GO:0048786=GO_REF:0000019, GO:0043005=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0031594=GO_REF:0000019, GO:0005783=GO_REF:0000054, GO:0005911=GO_REF:0000019, GO:0022857=GO_REF:0000002, GO:0006874=GO_REF:0000019, GO:0006836=GO_REF:0000037, GO:0030672=GO_REF:0000039, GO:0004872=GO_REF:0000019, GO:0016021=GO_REF:0000019} Q7L0J3 Synaptic vesicle glycoprotein 2A protein 20080205 {GO:0048786=IEA, GO:0043005=IEA, GO:0005737=IDA, GO:0031594=IEA, GO:0005783=IDA, GO:0005911=IEA, GO:0022857=IEA, GO:0006874=IEA, GO:0006836=IEA, GO:0030672=IEA, GO:0004872=IEA, GO:0016021=IEA} cellular calcium ion homeostasis, neurotransmitter transport cell-cell junction, cytoplasm, endoplasmic reticulum, integral to membrane, neuromuscular junction, neuron projection, presynaptic active zone, synaptic vesicle membrane receptor activity, transmembrane transporter activity Human SV2B UniProtKB UniProtKB {GO:0030054=GO_REF:0000037, GO:0001669=GO_REF:0000039, GO:0022857=GO_REF:0000002, GO:0006836=GO_REF:0000037, GO:0030672=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q7L1I2 Synaptic vesicle glycoprotein 2B protein 20130413 {GO:0030054=IEA, GO:0001669=IEA, GO:0022857=IEA, GO:0006836=IEA, GO:0030672=IEA, GO:0016021=IEA} neurotransmitter transport acrosomal vesicle, cell junction, integral to membrane, synaptic vesicle membrane transmembrane transporter activity Human UniProtKB-SubCell:SL-0260 SV2C UniProtKB UniProtKB {GO:0030054=GO_REF:0000037, GO:0022857=GO_REF:0000002, GO:0006836=GO_REF:0000037, GO:0030672=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q496J9 Synaptic vesicle glycoprotein 2C protein 20130413 {GO:0030054=IEA, GO:0022857=IEA, GO:0006836=IEA, GO:0030672=IEA, GO:0016021=IEA} neurotransmitter transport cell junction, integral to membrane, synaptic vesicle membrane transmembrane transporter activity Human UniProtKB-SubCell:SL-0260 SVEP1 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0016020=GO_REF:0000039, GO:0003682=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0005576=GO_REF:0000039, GO:0007155=GO_REF:0000037} Q4LDE5 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 protein 20130413 {GO:0005737=IEA, GO:0016020=IEA, GO:0003682=IEA, GO:0005509=IEA, GO:0005576=IEA, GO:0007155=IEA} cell adhesion cytoplasm, extracellular region, membrane calcium ion binding, chromatin binding Human UniProtKB-SubCell:SL-0162 SVIL HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0051015=PMID:12711699, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000052, GO:0007519=PMID:12711699, GO:0071437=GO_REF:0000039, GO:0007010=GO_REF:0000002, GO:0043034=PMID:12711699, GO:0002102=GO_REF:0000039, GO:0005634=PMID:12711699, GO:0003779=GO_REF:0000002, GO:0015629=GO_REF:0000052} O95425 Supervillin protein 20101115 {GO:0005737=IDA, GO:0051015=IDA, GO:0030054=IEA, GO:0005886=IDA, GO:0007519=IMP, GO:0071437=IEA, GO:0007010=IEA, GO:0043034=IDA, GO:0002102=IEA, GO:0005634=IDA, GO:0003779=IEA, GO:0015629=IDA} cytoskeleton organization, skeletal muscle tissue development actin cytoskeleton, cell junction, costamere, cytoplasm, invadopodium, nucleus, plasma membrane, podosome actin binding, actin filament binding Human SVIP UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0000139=GO_REF:0000039, GO:0030868=GO_REF:0000039} Q8NHG7 Small VCP/p97-interacting protein protein 20130413 {GO:0005886=IEA, GO:0000139=IEA, GO:0030868=IEA} Golgi membrane, plasma membrane, smooth endoplasmic reticulum membrane Human UniProtKB-SubCell:SL-0250 SVOPL UniProtKB UniProtKB {GO:0022857=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q8N434 Putative transporter SVOPL protein 20130413 {GO:0022857=IEA, GO:0016021=IEA} integral to membrane transmembrane transporter activity Human UniProtKB-KW:KW-0812 SWAP70 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0045190=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0005524=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0030027=GO_REF:0000039} Q9UH65 Switch-associated protein 70 protein 20080205 {GO:0005737=IDA, GO:0005543=IEA, GO:0005886=IDA, GO:0045190=IEA, GO:0005509=IEA, GO:0005634=IEA, GO:0005524=IEA, GO:0003677=IEA, GO:0030027=IEA} isotype switching cytoplasm, lamellipodium, nucleus, plasma membrane ATP binding, DNA binding, calcium ion binding, phospholipid binding Human SWI5 UniProtKB UniProtKB {GO:0005515=PMID:21252223, GO:0032798=PMID:21252223, GO:0000724=PMID:21252223, GO:0005634=GO_REF:0000024} Q1ZZU3 DNA repair protein SWI5 homolog protein 20110222 {GO:0005515=IPI, GO:0032798=IDA, GO:0000724=IMP, GO:0005634=ISS} double-strand break repair via homologous recombination Swi5-Sfr1 complex, nucleus protein binding Human UniProtKB:Q06609 SWSAP1 IntAct UniProtKB {GO:0005515=PMID:21965664, GO:0003697=PMID:21965664, GO:0006200=PMID:21965664, GO:0000724=PMID:21965664, GO:0050821=PMID:21965664, GO:0005634=GO_REF:0000039, GO:0097196=PMID:21965664, GO:0016887=PMID:21965664} Q6NVH7 ATPase SWSAP1 protein 20130415 {GO:0005515=IPI, GO:0003697=IDA, GO:0006200=IDA, GO:0000724=IMP, GO:0050821=IMP, GO:0005634=IEA, GO:0097196=IDA, GO:0016887=IDA} ATP catabolic process, double-strand break repair via homologous recombination, protein stabilization Shu complex, nucleus ATPase activity, protein binding, single-stranded DNA binding Human UniProtKB:Q19AV6 SYAP1 ENSEMBL UniProtKB {GO:0005634=GO_REF:0000019} Q96A49 Synapse-associated protein 1 protein 20130413 {GO:0005634=IEA} nucleus Human Ensembl:ENSMUSP00000033723 SYBU IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0000139=GO_REF:0000039, GO:0016023=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0019894=GO_REF:0000002, GO:0017075=GO_REF:0000002, GO:0005856=GO_REF:0000039} Q9NX95 Syntabulin protein 20130415 {GO:0005515=IPI, GO:0000139=IEA, GO:0016023=IEA, GO:0016021=IEA, GO:0019894=IEA, GO:0017075=IEA, GO:0005856=IEA} Golgi membrane, cytoplasmic membrane-bounded vesicle, cytoskeleton, integral to membrane kinesin binding, protein binding, syntaxin-1 binding Human UniProtKB:P54253 SYCP1 ENSEMBL UniProtKB {GO:0032880=GO_REF:0000019, GO:0000802=GO_REF:0000019, GO:0000801=GO_REF:0000019, GO:0007283=PMID:1464329, GO:0007130=GO_REF:0000019, GO:0001673=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0007131=PMID:1464329, GO:0051301=GO_REF:0000037} Q5VXJ5 Synaptonemal complex protein 1 protein 20130413 {GO:0032880=IEA, GO:0000802=IEA, GO:0000801=IEA, GO:0007283=TAS, GO:0007130=IEA, GO:0001673=IEA, GO:0003677=IEA, GO:0007131=TAS, GO:0051301=IEA} cell division, reciprocal meiotic recombination, regulation of protein localization, spermatogenesis, synaptonemal complex assembly central element, male germ cell nucleus, transverse filament DNA binding Human Ensembl:ENSMUSP00000029448 SYCP2 UniProtKB UniProtKB {GO:0000795=PMID:10341103, GO:0046982=GO_REF:0000019, GO:0006915=GO_REF:0000019, GO:0005634=PMID:10341103, GO:0000800=GO_REF:0000019, GO:0003677=PMID:10341103, GO:0009566=GO_REF:0000019, GO:0007128=PMID:9592139, GO:0048808=GO_REF:0000019, GO:0007143=GO_REF:0000019, GO:0007130=PMID:10341103, GO:0007140=GO_REF:0000019, GO:0051301=GO_REF:0000037} Q9BX26 Synaptonemal complex protein 2 protein 20030424 {GO:0000795=NAS, GO:0046982=IEA, GO:0006915=IEA, GO:0005634=NAS, GO:0000800=IEA, GO:0003677=NAS, GO:0009566=IEA, GO:0007128=NAS, GO:0048808=IEA, GO:0007143=IEA, GO:0007130=NAS, GO:0007140=IEA, GO:0051301=IEA} apoptotic process, cell division, female meiosis, fertilization, male genitalia morphogenesis, male meiosis, meiotic prophase I, synaptonemal complex assembly lateral element, nucleus, synaptonemal complex DNA binding, protein heterodimerization activity Human SYCP2L HPA UniProtKB {GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q5T4T6 Synaptonemal complex protein 2-like protein 20110516 {GO:0005730=IDA, GO:0005634=IDA} nucleolus, nucleus NOT Human SYCP3 UniProtKB UniProtKB {GO:0005694=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0035093=PMID:14643120, GO:0007141=PMID:15218256, GO:0051301=GO_REF:0000037} Q8IZU3 Synaptonemal complex protein 3 protein 20060124 {GO:0005694=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0035093=IMP, GO:0007141=NAS, GO:0051301=IEA} cell division, male meiosis I, spermatogenesis, exchange of chromosomal proteins chromosome, nucleus DNA binding Human SYDE1 Reactome UniProtKB {GO:0005622=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0007165=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0032862=GO_REF:0000024, GO:0005100=GO_REF:0000024, GO:0005829=Reactome:REACT_9982} Q6ZW31 Rho GTPase-activating protein SYDE1 protein 20130301 {GO:0005622=IEA, GO:0051056=TAS, GO:0007165=IEA, GO:0007264=TAS, GO:0032862=ISS, GO:0005100=ISS, GO:0005829=TAS} activation of Rho GTPase activity, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, intracellular Rho GTPase activator activity Human SYDE2 Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0007264=Reactome:REACT_11044, GO:0032862=GO_REF:0000024, GO:0005100=GO_REF:0000024, GO:0005829=Reactome:REACT_9982} Q5VT97 Rho GTPase-activating protein SYDE2 protein 20130301 {GO:0051056=TAS, GO:0007264=TAS, GO:0032862=ISS, GO:0005100=ISS, GO:0005829=TAS} activation of Rho GTPase activity, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol Rho GTPase activator activity Human SYF2 LIFEdb UniProtKB {GO:0000398=PMID:11991638, GO:0005634=GO_REF:0000054, GO:0071013=PMID:11991638} O95926 Pre-mRNA-splicing factor SYF2 protein 20100607 {GO:0000398=IC, GO:0005634=IDA, GO:0071013=IDA} mRNA splicing, via spliceosome catalytic step 2 spliceosome, nucleus Human SYK BHF-UCL UniProtKB {GO:0005515=PMID:23001182, GO:0046638=GO_REF:0000019, GO:0045401=GO_REF:0000019, GO:0043313=GO_REF:0000024, GO:0050731=GO_REF:0000019, GO:0002554=GO_REF:0000024, GO:0019815=GO_REF:0000019, GO:0046777=GO_REF:0000019, GO:0009887=PMID:7477352, GO:0046641=GO_REF:0000019, GO:0002366=GO_REF:0000024, GO:0070372=GO_REF:0000024, GO:0001945=GO_REF:0000024, GO:0042742=GO_REF:0000024, GO:0019901=GO_REF:0000019, GO:0045588=GO_REF:0000019, GO:0030593=PMID:12885943, GO:0032928=GO_REF:0000024, GO:0030168=Reactome:REACT_798, GO:0018108=GO_REF:0000019, GO:0043306=GO_REF:0000019, GO:0005178=PMID:12885943, GO:0007229=GO_REF:0000024, GO:0045087=Reactome:REACT_6802, GO:0038096=Reactome:REACT_160123, GO:0050853=GO_REF:0000024, GO:0045425=GO_REF:0000019, GO:0005886=Reactome:REACT_118834, GO:0008283=PMID:10963601, GO:0045579=GO_REF:0000019, GO:0010543=GO_REF:0000024, GO:0048514=GO_REF:0000024, GO:0050715=GO_REF:0000019, GO:0032009=GO_REF:0000024, GO:0050850=GO_REF:0000019, GO:0005829=Reactome:REACT_160316, GO:0050764=GO_REF:0000024, GO:0045780=GO_REF:0000024, GO:0002281=GO_REF:0000024, GO:0042101=PMID:8176201, GO:0007159=PMID:12885943, GO:0002283=GO_REF:0000024, GO:0019370=GO_REF:0000019, GO:0090330=GO_REF:0000024, GO:0033630=GO_REF:0000024, GO:0043366=GO_REF:0000019, GO:0090237=GO_REF:0000024, GO:0001525=GO_REF:0000037, GO:0007257=GO_REF:0000019, GO:0005524=GO_REF:0000019, GO:0002250=GO_REF:0000024, GO:0004672=PMID:12885943, GO:0007596=Reactome:REACT_604, GO:0019048=GO_REF:0000037, GO:0006468=GO_REF:0000024, GO:0004713=Reactome:REACT_147834, GO:0004715=Reactome:REACT_23800, GO:0004716=GO_REF:0000019, GO:0071226=GO_REF:0000024, GO:0007167=GO_REF:0000019} P43405 Tyrosine-protein kinase SYK protein 20121121 {GO:0005515=IPI, GO:0046638=IEA, GO:0045401=IEA, GO:0043313=ISS, GO:0050731=IEA, GO:0002554=ISS, GO:0019815=IEA, GO:0046777=IEA, GO:0009887=TAS, GO:0046641=IEA, GO:0002366=ISS, GO:0070372=ISS, GO:0001945=ISS, GO:0042742=ISS, GO:0019901=IEA, GO:0045588=IEA, GO:0030593=IDA, GO:0032928=ISS, GO:0030168=TAS, GO:0018108=IEA, GO:0043306=IEA, GO:0005178=IPI, GO:0007229=ISS, GO:0045087=TAS, GO:0038096=TAS, GO:0050853=ISS, GO:0045425=IEA, GO:0005886=TAS, GO:0008283=TAS, GO:0045579=IEA, GO:0010543=ISS, GO:0048514=ISS, GO:0050715=IEA, GO:0032009=ISS, GO:0050850=IEA, GO:0005829=TAS, GO:0050764=ISS, GO:0045780=ISS, GO:0002281=ISS, GO:0042101=IDA, GO:0007159=IDA, GO:0002283=ISS, GO:0019370=IEA, GO:0090330=ISS, GO:0033630=ISS, GO:0043366=IEA, GO:0090237=ISS, GO:0001525=IEA, GO:0007257=IEA, GO:0005524=IEA, GO:0002250=ISS, GO:0004672=NAS, GO:0007596=TAS, GO:0019048=IEA, GO:0006468=ISS, GO:0004713=TAS, GO:0004715=TAS, GO:0004716=IEA, GO:0071226=ISS, GO:0007167=IEA} B cell receptor signaling pathway, Fc-gamma receptor signaling pathway involved in phagocytosis, activation of JUN kinase activity, adaptive immune response, angiogenesis, beta selection, blood coagulation, blood vessel morphogenesis, cell proliferation, cellular response to molecule of fungal origin, defense response to bacterium, enzyme linked receptor protein signaling pathway, innate immune response, integrin-mediated signaling pathway, leukocyte activation involved in immune response, leukocyte cell-cell adhesion, leukotriene biosynthetic process, lymph vessel development, macrophage activation involved in immune response, neutrophil activation involved in immune response, neutrophil chemotaxis, organ morphogenesis, peptidyl-tyrosine phosphorylation, platelet activation, positive regulation of B cell differentiation, positive regulation of alpha-beta T cell differentiation, positive regulation of alpha-beta T cell proliferation, positive regulation of bone resorption, positive regulation of calcium-mediated signaling, positive regulation of cell adhesion mediated by integrin, positive regulation of cytokine secretion, positive regulation of gamma-delta T cell differentiation, positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, positive regulation of interleukin-3 biosynthetic process, positive regulation of mast cell degranulation, positive regulation of peptidyl-tyrosine phosphorylation, protein autophosphorylation, protein phosphorylation, regulation of ERK1 and ERK2 cascade, regulation of arachidonic acid secretion, regulation of neutrophil degranulation, regulation of phagocytosis, regulation of platelet activation, regulation of platelet aggregation, regulation of superoxide anion generation, serotonin secretion by platelet, virus-host interaction B cell receptor complex, T cell receptor complex, cytosol, early phagosome, plasma membrane ATP binding, integrin binding, non-membrane spanning protein tyrosine kinase activity, protein binding, protein kinase activity, protein kinase binding, protein tyrosine kinase activity, receptor signaling protein tyrosine kinase activity Human UniProtKB:P14317 SYMPK HPA UniProtKB {GO:0005515=PMID:18688255, GO:0006378=PMID:20861839, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0035307=PMID:20861839, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005654=PMID:8769423, GO:0005923=GO_REF:0000039, GO:0005856=GO_REF:0000039, GO:0007155=GO_REF:0000037} Q92797 Symplekin protein 20111111 {GO:0005515=IPI, GO:0006378=IMP, GO:0005737=IDA, GO:0005886=IDA, GO:0035307=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0005654=IDA, GO:0005923=IEA, GO:0005856=IEA, GO:0007155=IEA} cell adhesion, mRNA polyadenylation, positive regulation of protein dephosphorylation cytoplasm, cytoskeleton, nucleolus, nucleoplasm, nucleus, plasma membrane, tight junction protein binding Human SYN1 PINC UniProtKB {GO:0048786=GO_REF:0000019, GO:0005215=PMID:2110562, GO:0030054=GO_REF:0000037, GO:0000795=GO_REF:0000019, GO:0005794=GO_REF:0000039, GO:0007268=PMID:2110562, GO:0003779=GO_REF:0000037, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0007269=GO_REF:0000002, GO:0030425=GO_REF:0000019, GO:0005829=GO_REF:0000019, GO:0030672=GO_REF:0000019} P17600 Synapsin-1 protein 20030904 {GO:0048786=IEA, GO:0005215=TAS, GO:0030054=IEA, GO:0000795=IEA, GO:0005794=IEA, GO:0007268=TAS, GO:0003779=IEA, GO:0003824=IEA, GO:0005524=IEA, GO:0007269=IEA, GO:0030425=IEA, GO:0005829=IEA, GO:0030672=IEA} neurotransmitter secretion, synaptic transmission Golgi apparatus, cell junction, cytosol, dendrite, presynaptic active zone, synaptic vesicle membrane, synaptonemal complex ATP binding, actin binding, catalytic activity, transporter activity Human SYN2 PINC UniProtKB {GO:0030054=GO_REF:0000037, GO:0007268=PMID:8964517, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0007269=GO_REF:0000002, GO:0008021=GO_REF:0000002} Q92777 Synapsin-2 protein 20030904 {GO:0030054=IEA, GO:0007268=TAS, GO:0003824=IEA, GO:0005524=IEA, GO:0007269=IEA, GO:0008021=IEA} neurotransmitter secretion, synaptic transmission cell junction, synaptic vesicle ATP binding, catalytic activity Human SYN3 ENSEMBL UniProtKB {GO:0030054=GO_REF:0000037, GO:0030672=GO_REF:0000019, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000019, GO:0007269=GO_REF:0000002, GO:0008021=PMID:9539796} Q4TT46 Synapsin-3 protein 20130413 {GO:0030054=IEA, GO:0030672=IEA, GO:0003824=IEA, GO:0005524=IEA, GO:0007269=IEA, GO:0008021=TAS} neurotransmitter secretion cell junction, synaptic vesicle, synaptic vesicle membrane ATP binding, catalytic activity Human Ensembl:ENSMUSP00000113720 SYNC UniProtKB UniProtKB {GO:0005882=GO_REF:0000037, GO:0042383=GO_REF:0000019, GO:0048471=GO_REF:0000039, GO:0030018=GO_REF:0000019, GO:0031594=GO_REF:0000019, GO:0005198=GO_REF:0000002, GO:0045103=GO_REF:0000019, GO:0005829=GO_REF:0000019} Q9H7C4 Syncoilin protein 20130413 {GO:0005882=IEA, GO:0042383=IEA, GO:0048471=IEA, GO:0030018=IEA, GO:0031594=IEA, GO:0005198=IEA, GO:0045103=IEA, GO:0005829=IEA} intermediate filament-based process Z disc, cytosol, intermediate filament, neuromuscular junction, perinuclear region of cytoplasm, sarcolemma structural molecule activity Human UniProtKB-SubCell:SL-0198 SYNCRIP IntAct UniProtKB {GO:0005515=PMID:12674497, GO:0008380=PMID:9847309, GO:0017148=PMID:23071094, GO:0006396=PMID:9847309, GO:0070934=PMID:19029303, GO:0005783=GO_REF:0000039, GO:0003723=PMID:9847309, GO:0005634=PMID:9847309, GO:0071013=PMID:11991638, GO:0005737=GO_REF:0000019, GO:0071346=PMID:15479637, GO:0000166=GO_REF:0000002, GO:0000398=PMID:11991638, GO:0019048=GO_REF:0000037, GO:0030529=PMID:15479637, GO:0008143=GO_REF:0000019, GO:0005654=GO_REF:0000039, GO:0071204=GO_REF:0000024, GO:0070937=PMID:19029303} O60506 Heterogeneous nuclear ribonucleoprotein Q protein 20130415 {GO:0005515=IPI, GO:0008380=TAS, GO:0017148=IDA, GO:0006396=TAS, GO:0070934=IMP, GO:0005783=IEA, GO:0003723=TAS, GO:0005634=TAS, GO:0071013=IDA, GO:0005737=IEA, GO:0071346=IDA, GO:0000166=IEA, GO:0000398=IC, GO:0019048=IEA, GO:0030529=IDA, GO:0008143=IEA, GO:0005654=IEA, GO:0071204=ISS, GO:0070937=IDA} CRD-mediated mRNA stabilization, RNA processing, RNA splicing, cellular response to interferon-gamma, mRNA splicing, via spliceosome, negative regulation of translation, virus-host interaction CRD-mediated mRNA stability complex, catalytic step 2 spliceosome, cytoplasm, endoplasmic reticulum, histone pre-mRNA 3'end processing complex, nucleoplasm, nucleus, ribonucleoprotein complex RNA binding, nucleotide binding, poly(A) RNA binding, protein binding Human UniProtKB:Q14103-4 SYNE1 HPA UniProtKB {GO:0005515=PMID:22632968, GO:0008219=GO_REF:0000037, GO:0031965=GO_REF:0000052, GO:0006997=PMID:11792814, GO:0005794=PMID:12808039, GO:0090292=PMID:11801724, GO:0005730=GO_REF:0000052, GO:0034993=PMID:18396275, GO:0003779=PMID:12408964, GO:0005634=GO_REF:0000052, GO:0090286=PMID:18396275, GO:0005635=PMID:11792814, GO:0030017=PMID:12408964, GO:0042803=GO_REF:0000024, GO:0042692=PMID:11792814, GO:0005640=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0045211=PMID:10878022, GO:0007030=PMID:12808039, GO:0016021=PMID:11792814, GO:0005856=GO_REF:0000039, GO:0005521=PMID:11801724} Q8NF91 Nesprin-1 protein 20101115 {GO:0005515=IPI, GO:0008219=IEA, GO:0031965=IDA, GO:0006997=NAS, GO:0005794=IDA, GO:0090292=IDA, GO:0005730=IDA, GO:0034993=IDA, GO:0003779=IDA, GO:0005634=IDA, GO:0090286=IDA, GO:0005635=IDA, GO:0030017=IDA, GO:0042803=ISS, GO:0042692=IDA, GO:0005640=IEA, GO:0005737=IDA, GO:0045211=IDA, GO:0007030=IDA, GO:0016021=IDA, GO:0005856=IEA, GO:0005521=IPI} Golgi organization, cell death, cytoskeletal anchoring at nuclear membrane, muscle cell differentiation, nuclear matrix anchoring at nuclear membrane, nucleus organization Golgi apparatus, SUN-KASH complex, cytoplasm, cytoskeleton, integral to membrane, nuclear envelope, nuclear membrane, nuclear outer membrane, nucleolus, nucleus, postsynaptic membrane, sarcomere actin binding, lamin binding, protein binding, protein homodimerization activity Human SYNE2 HPA UniProtKB {GO:0005515=PMID:22632968, GO:0034504=GO_REF:0000019, GO:0030018=PMID:15671068, GO:0007097=PMID:20724637, GO:0031527=PMID:15671068, GO:0034993=PMID:18396275, GO:0005634=GO_REF:0000052, GO:0090286=PMID:18396275, GO:0005635=PMID:15671068, GO:0005640=GO_REF:0000039, GO:0010761=GO_REF:0000019, GO:0051642=PMID:20724637, GO:0005737=PMID:15671068, GO:0031022=GO_REF:0000024, GO:0006998=GO_REF:0000019, GO:0005856=GO_REF:0000039, GO:0031965=GO_REF:0000052, GO:0030335=GO_REF:0000024, GO:0031258=PMID:15671068, GO:0033017=GO_REF:0000039, GO:0003779=GO_REF:0000024, GO:0031981=PMID:15671068, GO:0007163=GO_REF:0000019, GO:0016529=PMID:15671068, GO:0044429=PMID:15671068, GO:0005654=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0005925=PMID:15671068} Q8WXH0 Nesprin-2 protein 20101115 {GO:0005515=IPI, GO:0034504=IEA, GO:0030018=IDA, GO:0007097=IMP, GO:0031527=IDA, GO:0034993=IDA, GO:0005634=IDA, GO:0090286=IDA, GO:0005635=IDA, GO:0005640=IEA, GO:0010761=IEA, GO:0051642=IMP, GO:0005737=IDA, GO:0031022=ISS, GO:0006998=IEA, GO:0005856=IEA, GO:0031965=IDA, GO:0030335=ISS, GO:0031258=IDA, GO:0033017=IEA, GO:0003779=ISS, GO:0031981=IDA, GO:0007163=IEA, GO:0016529=IDA, GO:0044429=IDA, GO:0005654=IEA, GO:0016021=IEA, GO:0005925=IDA} centrosome localization, cytoskeletal anchoring at nuclear membrane, establishment or maintenance of cell polarity, fibroblast migration, nuclear envelope organization, nuclear migration, nuclear migration along microfilament, positive regulation of cell migration, protein localization to nucleus SUN-KASH complex, Z disc, cytoplasm, cytoskeleton, filopodium membrane, focal adhesion, integral to membrane, lamellipodium membrane, mitochondrial part, nuclear envelope, nuclear lumen, nuclear membrane, nuclear outer membrane, nucleoplasm, nucleus, sarcoplasmic reticulum, sarcoplasmic reticulum membrane actin binding, protein binding Human SYNGAP1 UniProtKB UniProtKB {GO:0051056=GO_REF:0000002, GO:0007389=GO_REF:0000019, GO:0017124=GO_REF:0000037, GO:0043066=GO_REF:0000019, GO:0031235=GO_REF:0000033, GO:0050803=GO_REF:0000019, GO:0007265=GO_REF:0000019, GO:0016358=GO_REF:0000019, GO:0005099=GO_REF:0000033, GO:0005622=GO_REF:0000002, GO:0046580=GO_REF:0000024, GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000033, GO:0005543=GO_REF:0000002, GO:0032320=GO_REF:0000033, GO:0048167=GO_REF:0000024, GO:0043198=GO_REF:0000019, GO:0008542=GO_REF:0000019, GO:0048169=GO_REF:0000019, GO:0043408=GO_REF:0000019, GO:0043113=GO_REF:0000019, GO:0050771=GO_REF:0000019, GO:0005097=GO_REF:0000019, GO:0005096=GO_REF:0000038} Q96PV0 Ras GTPase-activating protein SynGAP protein 20111110 {GO:0051056=IEA, GO:0007389=IEA, GO:0017124=IEA, GO:0043066=IEA, GO:0031235=IBA, GO:0050803=IEA, GO:0007265=IEA, GO:0016358=IEA, GO:0005099=IBA, GO:0005622=IEA, GO:0046580=ISS, GO:0007165=IEA, GO:0005737=IBA, GO:0005543=IEA, GO:0032320=IBA, GO:0048167=ISS, GO:0043198=IEA, GO:0008542=IEA, GO:0048169=IEA, GO:0043408=IEA, GO:0043113=IEA, GO:0050771=IEA, GO:0005097=IEA, GO:0005096=IEA} Ras protein signal transduction, dendrite development, negative regulation of Ras protein signal transduction, negative regulation of apoptotic process, negative regulation of axonogenesis, pattern specification process, positive regulation of Ras GTPase activity, receptor clustering, regulation of MAPK cascade, regulation of long-term neuronal synaptic plasticity, regulation of small GTPase mediated signal transduction, regulation of synapse structure and activity, regulation of synaptic plasticity, signal transduction, visual learning cytoplasm, dendritic shaft, intracellular, intrinsic to internal side of plasma membrane GTPase activator activity, Rab GTPase activator activity, Ras GTPase activator activity, SH3 domain binding, phospholipid binding Human UniProtKB:Q9QUH6 SYNGR1 UniProtKB UniProtKB {GO:0042470=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0048169=GO_REF:0000024, GO:0030672=GO_REF:0000019, GO:0006605=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0048172=GO_REF:0000024} O43759 Synaptogyrin-1 protein 20090922 {GO:0042470=IEA, GO:0030054=IEA, GO:0048169=ISS, GO:0030672=IEA, GO:0006605=IEA, GO:0016021=IEA, GO:0048172=ISS} protein targeting, regulation of long-term neuronal synaptic plasticity, regulation of short-term neuronal synaptic plasticity cell junction, integral to membrane, melanosome, synaptic vesicle membrane Human UniProtKB:O55100 SYNGR2 UniProtKB UniProtKB {GO:0006605=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0008021=GO_REF:0000019} Q3KQZ2 Synaptogyrin-2 protein 20130413 {GO:0006605=IEA, GO:0016021=IEA, GO:0008021=IEA} protein targeting integral to membrane, synaptic vesicle Human UniProtKB-KW:KW-0812 SYNGR3 UniProtKB UniProtKB {GO:0047485=GO_REF:0000019, GO:0031594=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0032411=GO_REF:0000024, GO:0016021=PMID:9760194, GO:0042169=GO_REF:0000019, GO:0008021=GO_REF:0000024} O43761 Synaptogyrin-3 protein 20121017 {GO:0047485=IEA, GO:0031594=IEA, GO:0030054=IEA, GO:0032411=ISS, GO:0016021=NAS, GO:0042169=IEA, GO:0008021=ISS} positive regulation of transporter activity cell junction, integral to membrane, neuromuscular junction, synaptic vesicle SH2 domain binding, protein N-terminus binding Human SYNJ1 Reactome UniProtKB {GO:0016082=GO_REF:0000019, GO:0043647=Reactome:REACT_150352, GO:0006661=Reactome:REACT_121025, GO:0003723=GO_REF:0000037, GO:0044281=Reactome:REACT_111217, GO:0048488=PMID:9428629, GO:0004445=PMID:9428629, GO:0006796=PMID:9428629, GO:0003676=GO_REF:0000002, GO:0030117=GO_REF:0000019, GO:0005829=Reactome:REACT_150347, GO:0004439=GO_REF:0000003, GO:0042578=GO_REF:0000002, GO:0000166=GO_REF:0000002, GO:0046855=GO_REF:0000019, GO:0046856=GO_REF:0000002, GO:0007612=GO_REF:0000019, GO:0006644=Reactome:REACT_121175, GO:0016191=GO_REF:0000019} O43426 Synaptojanin-1 protein 20130301 {GO:0016082=IEA, GO:0043647=TAS, GO:0006661=TAS, GO:0003723=IEA, GO:0044281=TAS, GO:0048488=TAS, GO:0004445=TAS, GO:0006796=TAS, GO:0003676=IEA, GO:0030117=IEA, GO:0005829=TAS, GO:0004439=IEA, GO:0042578=IEA, GO:0000166=IEA, GO:0046855=IEA, GO:0046856=IEA, GO:0007612=IEA, GO:0006644=TAS, GO:0016191=IEA} inositol phosphate dephosphorylation, inositol phosphate metabolic process, learning, phosphate-containing compound metabolic process, phosphatidylinositol biosynthetic process, phosphatidylinositol dephosphorylation, phospholipid metabolic process, small molecule metabolic process, synaptic vesicle endocytosis, synaptic vesicle priming, synaptic vesicle uncoating cytosol, membrane coat RNA binding, inositol-polyphosphate 5-phosphatase activity, nucleic acid binding, nucleotide binding, phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, phosphoric ester hydrolase activity Human SYNJ2 InterPro UniProtKB {GO:0005515=PMID:20936779, GO:0004439=GO_REF:0000003, GO:0042578=GO_REF:0000002, GO:0006661=Reactome:REACT_121025, GO:0016020=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0046856=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0006644=Reactome:REACT_121175, GO:0003676=GO_REF:0000002, GO:0005829=Reactome:REACT_121287} Q5TA15 Synaptojanin-2 protein 20130413 {GO:0005515=IPI, GO:0004439=IEA, GO:0042578=IEA, GO:0006661=TAS, GO:0016020=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0046856=IEA, GO:0044281=TAS, GO:0006644=TAS, GO:0003676=IEA, GO:0005829=TAS} phosphatidylinositol biosynthetic process, phosphatidylinositol dephosphorylation, phospholipid metabolic process, small molecule metabolic process cytosol, membrane RNA binding, nucleic acid binding, nucleotide binding, phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, phosphoric ester hydrolase activity, protein binding Human InterPro:IPR002013 SYNJ2BP HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0048312=GO_REF:0000019, GO:0031307=GO_REF:0000019, GO:0008022=GO_REF:0000019} P57105 Synaptojanin-2-binding protein protein 20080205 {GO:0005739=IDA, GO:0048312=IEA, GO:0031307=IEA, GO:0008022=IEA} intracellular distribution of mitochondria integral to mitochondrial outer membrane, mitochondrion protein C-terminus binding Human SYNM UniProtKB UniProtKB {GO:0005515=PMID:16777071, GO:0005882=PMID:11737198, GO:0060053=PMID:14552890, GO:0005912=PMID:16777071, GO:0016020=GO_REF:0000019, GO:0005198=GO_REF:0000002, GO:0045104=PMID:16777071, GO:0017166=PMID:18028034, GO:0005200=PMID:11737198, GO:0043034=PMID:18342854, GO:0008307=PMID:11737198, GO:0019215=GO_REF:0000024} O15061 Synemin protein 20090116 {GO:0005515=IPI, GO:0005882=IDA, GO:0060053=TAS, GO:0005912=IDA, GO:0016020=IEA, GO:0005198=IEA, GO:0045104=TAS, GO:0017166=IDA, GO:0005200=IDA, GO:0043034=IDA, GO:0008307=IDA, GO:0019215=ISS} intermediate filament cytoskeleton organization adherens junction, costamere, intermediate filament, membrane, neurofilament cytoskeleton intermediate filament binding, protein binding, structural constituent of cytoskeleton, structural constituent of muscle, structural molecule activity, vinculin binding Human UniProtKB:P11532 SYNPO LIFEdb UniProtKB {GO:0005515=PMID:18596123, GO:0001725=GO_REF:0000019, GO:0005886=GO_REF:0000037, GO:0051492=GO_REF:0000019, GO:0014069=GO_REF:0000039, GO:0003779=GO_REF:0000024, GO:0015629=GO_REF:0000054, GO:0005737=GO_REF:0000037, GO:0043197=PMID:15841212, GO:0045211=GO_REF:0000037, GO:0032233=GO_REF:0000019, GO:0043204=GO_REF:0000039, GO:0005923=GO_REF:0000039} Q8N3V7 Synaptopodin protein 20100607 {GO:0005515=IPI, GO:0001725=IEA, GO:0005886=IEA, GO:0051492=IEA, GO:0014069=IEA, GO:0003779=ISS, GO:0015629=IDA, GO:0005737=IEA, GO:0043197=TAS, GO:0045211=IEA, GO:0032233=IEA, GO:0043204=IEA, GO:0005923=IEA} positive regulation of actin filament bundle assembly, regulation of stress fiber assembly actin cytoskeleton, cytoplasm, dendritic spine, perikaryon, plasma membrane, postsynaptic density, postsynaptic membrane, stress fiber, tight junction actin binding, protein binding Human SYNPO2 IntAct UniProtKB {GO:0005515=PMID:21643011, GO:0071889=GO_REF:0000024, GO:0051371=GO_REF:0000024, GO:0030018=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0003779=GO_REF:0000037, GO:0015629=GO_REF:0000054} Q9UMS6 Synaptopodin-2 protein 20130415 {GO:0005515=IPI, GO:0071889=ISS, GO:0051371=ISS, GO:0030018=ISS, GO:0005634=ISS, GO:0003779=IEA, GO:0015629=IDA} Z disc, actin cytoskeleton, nucleus 14-3-3 protein binding, actin binding, muscle alpha-actinin binding, protein binding Human UniProtKB:Q13418 SYNPO2L UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0003779=GO_REF:0000037, GO:0005856=GO_REF:0000039} Q9H987 Synaptopodin 2-like protein protein 20130413 {GO:0005737=IEA, GO:0003779=IEA, GO:0005856=IEA} cytoplasm, cytoskeleton actin binding Human UniProtKB-SubCell:SL-0090 SYNRG PINC UniProtKB {GO:0005737=PMID:10477754, GO:0005794=PMID:10477754, GO:0030121=PMID:10477754, GO:0005509=GO_REF:0000002, GO:0006886=PMID:10477754, GO:0006897=GO_REF:0000037} Q9UMZ2 Synergin gamma protein 20030904 {GO:0005737=TAS, GO:0005794=TAS, GO:0030121=TAS, GO:0005509=IEA, GO:0006886=TAS, GO:0006897=IEA} endocytosis, intracellular protein transport AP-1 adaptor complex, Golgi apparatus, cytoplasm calcium ion binding Human SYP UniProtKB UniProtKB {GO:0005215=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0048499=PMID:10620806, GO:0032403=GO_REF:0000019, GO:0042802=GO_REF:0000019, GO:0015485=PMID:10620806, GO:0048169=GO_REF:0000024, GO:0030672=GO_REF:0000019, GO:0017075=GO_REF:0000019, GO:0042169=GO_REF:0000019, GO:0044306=GO_REF:0000019, GO:0048786=GO_REF:0000019, GO:0071310=GO_REF:0000019, GO:0005509=GO_REF:0000029, GO:0060076=GO_REF:0000019, GO:0006897=GO_REF:0000024, GO:0008021=GO_REF:0000002, GO:0043234=GO_REF:0000019, GO:0042734=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0030285=PMID:1975480, GO:0016188=PMID:10620806, GO:0016021=GO_REF:0000038, GO:0048172=GO_REF:0000024, GO:2000474=GO_REF:0000024} P08247 Synaptophysin protein 20090922 {GO:0005215=IEA, GO:0030054=IEA, GO:0048499=NAS, GO:0032403=IEA, GO:0042802=IEA, GO:0015485=IDA, GO:0048169=ISS, GO:0030672=IEA, GO:0017075=IEA, GO:0042169=IEA, GO:0044306=IEA, GO:0048786=IEA, GO:0071310=IEA, GO:0005509=NAS, GO:0060076=IEA, GO:0006897=ISS, GO:0008021=IEA, GO:0043234=IEA, GO:0042734=IEA, GO:0016020=IEA, GO:0030285=NAS, GO:0016188=NAS, GO:0016021=IEA, GO:0048172=ISS, GO:2000474=ISS} cellular response to organic substance, endocytosis, regulation of long-term neuronal synaptic plasticity, regulation of opioid receptor signaling pathway, regulation of short-term neuronal synaptic plasticity, synaptic vesicle maturation, synaptic vesicle membrane organization cell junction, excitatory synapse, integral to membrane, integral to synaptic vesicle membrane, membrane, neuron projection terminus, presynaptic active zone, presynaptic membrane, protein complex, synaptic vesicle, synaptic vesicle membrane SH2 domain binding, calcium ion binding, cholesterol binding, identical protein binding, protein complex binding, syntaxin-1 binding, transporter activity Human UniProtKB:Q62277 SYPL1 PINC UniProtKB {GO:0042470=GO_REF:0000039, GO:0005215=GO_REF:0000002, GO:0005887=PMID:8034131, GO:0007268=PMID:8034131, GO:0016021=PMID:1730063, GO:0030141=GO_REF:0000019, GO:0030659=GO_REF:0000039, GO:0008021=GO_REF:0000002} Q16563 Synaptophysin-like protein 1 protein 20030904 {GO:0042470=IEA, GO:0005215=IEA, GO:0005887=TAS, GO:0007268=TAS, GO:0016021=TAS, GO:0030141=IEA, GO:0030659=IEA, GO:0008021=IEA} synaptic transmission cytoplasmic vesicle membrane, integral to membrane, integral to plasma membrane, melanosome, secretory granule, synaptic vesicle transporter activity Human SYPL2 ENSEMBL UniProtKB {GO:0005215=GO_REF:0000002, GO:0006874=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0008021=GO_REF:0000002} Q5VXT5 Synaptophysin-like protein 2 protein 20130413 {GO:0005215=IEA, GO:0006874=IEA, GO:0016021=IEA, GO:0008021=IEA} cellular calcium ion homeostasis integral to membrane, synaptic vesicle transporter activity Human Ensembl:ENSMUSP00000029486 SYS1 UniProtKB UniProtKB {GO:0000139=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0015031=GO_REF:0000037} Q8N2H4 Protein SYS1 homolog protein 20130413 {GO:0000139=IEA, GO:0016021=IEA, GO:0015031=IEA} protein transport Golgi membrane, integral to membrane Human UniProtKB-SubCell:SL-0134 SYT1 IntAct UniProtKB {GO:0060201=Reactome:REACT_15483, GO:0005515=PMID:20098747, GO:0070083=Reactome:REACT_15533, GO:0005516=GO_REF:0000019, GO:0005215=GO_REF:0000002, GO:0043005=GO_REF:0000019, GO:0005513=PMID:11438518, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_23813, GO:0007268=Reactome:REACT_13685, GO:0031045=GO_REF:0000019, GO:0060203=Reactome:REACT_12617, GO:0007269=Reactome:REACT_13723, GO:0042802=GO_REF:0000019, GO:0017158=GO_REF:0000019, GO:0005544=GO_REF:0000019, GO:0005545=PMID:11438518, GO:0005543=PMID:1840599, GO:0030276=GO_REF:0000019, GO:0017157=PMID:11438518, GO:0030672=GO_REF:0000039, GO:0051260=PMID:11438518, GO:0017075=PMID:11438518, GO:0019905=GO_REF:0000019, GO:0005509=GO_REF:0000019, GO:0014047=Reactome:REACT_12591, GO:0016079=GO_REF:0000019, GO:0060076=GO_REF:0000019, GO:0008021=PMID:11438518, GO:0030666=Reactome:REACT_11217, GO:0042734=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0042584=GO_REF:0000039, GO:0061202=Reactome:REACT_23973, GO:0016021=GO_REF:0000037, GO:0050750=PMID:15082773, GO:0048306=GO_REF:0000019} P21579 Synaptotagmin-1 protein 20130415 {GO:0060201=TAS, GO:0005515=IPI, GO:0070083=TAS, GO:0005516=IEA, GO:0005215=IEA, GO:0043005=IEA, GO:0005513=TAS, GO:0030054=IEA, GO:0005886=TAS, GO:0007268=TAS, GO:0031045=IEA, GO:0060203=TAS, GO:0007269=TAS, GO:0042802=IEA, GO:0017158=IEA, GO:0005544=IEA, GO:0005545=TAS, GO:0005543=TAS, GO:0030276=IEA, GO:0017157=TAS, GO:0030672=IEA, GO:0051260=TAS, GO:0017075=TAS, GO:0019905=IEA, GO:0005509=IEA, GO:0014047=TAS, GO:0016079=IEA, GO:0060076=IEA, GO:0008021=TAS, GO:0030666=TAS, GO:0042734=IEA, GO:0016020=IEA, GO:0042584=IEA, GO:0061202=TAS, GO:0016021=IEA, GO:0050750=IDA, GO:0048306=IEA} detection of calcium ion, glutamate secretion, neurotransmitter secretion, protein homooligomerization, regulation of calcium ion-dependent exocytosis, regulation of exocytosis, synaptic transmission, synaptic vesicle exocytosis cell junction, chromaffin granule membrane, clathrin-sculpted acetylcholine transport vesicle membrane, clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane, clathrin-sculpted glutamate transport vesicle membrane, clathrin-sculpted monoamine transport vesicle membrane, dense core granule, endocytic vesicle membrane, excitatory synapse, integral to membrane, membrane, neuron projection, plasma membrane, presynaptic membrane, synaptic vesicle, synaptic vesicle membrane 1-phosphatidylinositol binding, calcium ion binding, calcium-dependent phospholipid binding, calcium-dependent protein binding, calmodulin binding, clathrin binding, identical protein binding, low-density lipoprotein particle receptor binding, phospholipid binding, protein binding, syntaxin binding, syntaxin-1 binding, transporter activity Human UniProtKB:Q9Y6K9 SYT10 UniProtKB UniProtKB {GO:0005215=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0046982=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0006950=GO_REF:0000019, GO:0030672=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0042803=GO_REF:0000019, GO:0008021=GO_REF:0000002} Q6XYQ8 Synaptotagmin-10 protein 20130413 {GO:0005215=IEA, GO:0030054=IEA, GO:0046982=IEA, GO:0016020=IEA, GO:0006950=IEA, GO:0030672=IEA, GO:0016021=IEA, GO:0046872=IEA, GO:0042803=IEA, GO:0008021=IEA} response to stress cell junction, integral to membrane, membrane, synaptic vesicle, synaptic vesicle membrane metal ion binding, protein heterodimerization activity, protein homodimerization activity, transporter activity Human UniProtKB-SubCell:SL-0260 SYT11 IntAct UniProtKB {GO:0005515=PMID:22645275, GO:0005215=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005887=GO_REF:0000019, GO:0030672=GO_REF:0000039, GO:0046872=GO_REF:0000037, GO:0008021=GO_REF:0000002} Q9BT88 Synaptotagmin-11 protein 20130415 {GO:0005515=IPI, GO:0005215=IEA, GO:0030054=IEA, GO:0005887=IEA, GO:0030672=IEA, GO:0046872=IEA, GO:0008021=IEA} cell junction, integral to plasma membrane, synaptic vesicle, synaptic vesicle membrane metal ion binding, protein binding, transporter activity Human UniProtKB:Q9NQ11 SYT12 UniProtKB UniProtKB {GO:0030054=GO_REF:0000037, GO:0030672=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q8IV01 Synaptotagmin-12 protein 20130413 {GO:0030054=IEA, GO:0030672=IEA, GO:0016021=IEA} cell junction, integral to membrane, synaptic vesicle membrane Human UniProtKB-SubCell:SL-0260 SYT13 LIFEdb UniProtKB {GO:0030133=GO_REF:0000054, GO:0005887=GO_REF:0000019, GO:0016192=GO_REF:0000019} Q7L8C5 Synaptotagmin-13 protein 20100607 {GO:0030133=IDA, GO:0005887=IEA, GO:0016192=IEA} vesicle-mediated transport integral to plasma membrane, transport vesicle Human SYT14 UniProtKB UniProtKB {GO:0008219=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q8NB59 Synaptotagmin-14 protein 20130413 {GO:0008219=IEA, GO:0016021=IEA} cell death integral to membrane Human UniProtKB-KW:KW-0812 SYT15 UniProtKB UniProtKB {GO:0005215=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0019898=GO_REF:0000019, GO:0008021=GO_REF:0000002} Q9BQS2 Synaptotagmin-15 protein 20130413 {GO:0005215=IEA, GO:0005886=IEA, GO:0016020=IEA, GO:0016021=IEA, GO:0019898=IEA, GO:0008021=IEA} extrinsic to membrane, integral to membrane, membrane, plasma membrane, synaptic vesicle transporter activity Human UniProtKB-SubCell:SL-0039 SYT16 ENSEMBL UniProtKB {GO:0005543=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0042803=GO_REF:0000019} Q17RD7 Synaptotagmin-16 protein 20130413 {GO:0005543=IEA, GO:0046982=IEA, GO:0042803=IEA} phospholipid binding, protein heterodimerization activity, protein homodimerization activity Human Ensembl:ENSMUSP00000106081 SYT17 UniProtKB UniProtKB {GO:0005802=GO_REF:0000019, GO:0005215=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0008021=GO_REF:0000002} Q9BSW7 Synaptotagmin-17 protein 20130413 {GO:0005802=IEA, GO:0005215=IEA, GO:0016020=IEA, GO:0008021=IEA} membrane, synaptic vesicle, trans-Golgi network transporter activity Human UniProtKB-SubCell:SL-0162 SYT2 HPA UniProtKB {GO:0005515=PMID:19234194, GO:0005215=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_11086, GO:0005509=GO_REF:0000019, GO:0007268=Reactome:REACT_13685, GO:0007269=Reactome:REACT_11184, GO:0043231=GO_REF:0000052, GO:0005544=GO_REF:0000019, GO:0030666=Reactome:REACT_11217, GO:0042584=GO_REF:0000039, GO:0030672=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q8N9I0 Synaptotagmin-2 protein 20101115 {GO:0005515=IPI, GO:0005215=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0005509=IEA, GO:0007268=TAS, GO:0007269=TAS, GO:0043231=IDA, GO:0005544=IEA, GO:0030666=TAS, GO:0042584=IEA, GO:0030672=IEA, GO:0016021=IEA} neurotransmitter secretion, synaptic transmission cell junction, chromaffin granule membrane, endocytic vesicle membrane, integral to membrane, intracellular membrane-bounded organelle, plasma membrane, synaptic vesicle membrane calcium ion binding, calcium-dependent phospholipid binding, protein binding, transporter activity Human SYT3 LIFEdb UniProtKB {GO:0019905=GO_REF:0000019, GO:0005544=GO_REF:0000019, GO:0005215=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0030276=GO_REF:0000019, GO:0030672=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0005768=GO_REF:0000054} Q9BQG1 Synaptotagmin-3 protein 20100607 {GO:0019905=IEA, GO:0005544=IEA, GO:0005215=IEA, GO:0030054=IEA, GO:0030276=IEA, GO:0030672=IEA, GO:0016021=IEA, GO:0046872=IEA, GO:0005768=IDA} cell junction, endosome, integral to membrane, synaptic vesicle membrane calcium-dependent phospholipid binding, clathrin binding, metal ion binding, syntaxin binding, transporter activity Human SYT4 UniProtKB UniProtKB {GO:0043005=GO_REF:0000019, GO:0005215=GO_REF:0000002, GO:0048471=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0016020=GO_REF:0000002, GO:0030276=GO_REF:0000019, GO:0005509=GO_REF:0000019, GO:0030672=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0007269=GO_REF:0000019, GO:0008021=GO_REF:0000002} Q9H2B2 Synaptotagmin-4 protein 20130413 {GO:0043005=IEA, GO:0005215=IEA, GO:0048471=IEA, GO:0030054=IEA, GO:0016020=IEA, GO:0030276=IEA, GO:0005509=IEA, GO:0030672=IEA, GO:0016021=IEA, GO:0007269=IEA, GO:0008021=IEA} neurotransmitter secretion cell junction, integral to membrane, membrane, neuron projection, perinuclear region of cytoplasm, synaptic vesicle, synaptic vesicle membrane calcium ion binding, clathrin binding, transporter activity Human UniProtKB-SubCell:SL-0260 SYT5 Reactome UniProtKB {GO:0019905=GO_REF:0000019, GO:0005215=GO_REF:0000002, GO:0043005=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0046982=GO_REF:0000019, GO:0007268=PMID:9177789, GO:0031045=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0008021=GO_REF:0000002, GO:0005544=GO_REF:0000019, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0016020=GO_REF:0000002, GO:0030276=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0030672=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0055038=GO_REF:0000039} O00445 Synaptotagmin-5 protein 20130213 {GO:0019905=IEA, GO:0005215=IEA, GO:0043005=IEA, GO:0048471=IEA, GO:0030054=IEA, GO:0046982=IEA, GO:0007268=TAS, GO:0031045=IEA, GO:0044281=TAS, GO:0046872=IEA, GO:0008021=IEA, GO:0005544=IEA, GO:0006112=TAS, GO:0050796=TAS, GO:0016020=IEA, GO:0030276=IEA, GO:0043025=IEA, GO:0030672=IEA, GO:0016021=IEA, GO:0055038=IEA} energy reserve metabolic process, regulation of insulin secretion, small molecule metabolic process, synaptic transmission cell junction, dense core granule, integral to membrane, membrane, neuron projection, neuronal cell body, perinuclear region of cytoplasm, recycling endosome membrane, synaptic vesicle, synaptic vesicle membrane calcium-dependent phospholipid binding, clathrin binding, metal ion binding, protein heterodimerization activity, syntaxin binding, transporter activity Human SYT6 BHF-UCL UniProtKB {GO:0019905=PMID:7791877, GO:0005215=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0046982=GO_REF:0000019, GO:0005886=GO_REF:0000024, GO:0097038=GO_REF:0000024, GO:0042803=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0005829=GO_REF:0000024, GO:0005544=PMID:7791877, GO:0060478=PMID:11437455, GO:0030276=PMID:7791877, GO:0030672=GO_REF:0000039, GO:0007340=GO_REF:0000019, GO:0016021=GO_REF:0000024, GO:0019898=GO_REF:0000024, GO:0048306=GO_REF:0000019} Q5T7P8 Synaptotagmin-6 protein 20110623 {GO:0019905=IDA, GO:0005215=IEA, GO:0030054=IEA, GO:0046982=IEA, GO:0005886=ISS, GO:0097038=ISS, GO:0042803=ISS, GO:0046872=IEA, GO:0005829=ISS, GO:0005544=IDA, GO:0060478=IMP, GO:0030276=IDA, GO:0030672=IEA, GO:0007340=IEA, GO:0016021=ISS, GO:0019898=ISS, GO:0048306=IEA} acrosomal vesicle exocytosis, acrosome reaction cell junction, cytosol, extrinsic to membrane, integral to membrane, perinuclear endoplasmic reticulum, plasma membrane, synaptic vesicle membrane calcium-dependent phospholipid binding, calcium-dependent protein binding, clathrin binding, metal ion binding, protein heterodimerization activity, protein homodimerization activity, syntaxin binding, transporter activity Human SYT7 UniProtKB UniProtKB {GO:0017158=GO_REF:0000019, GO:0005215=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0050796=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0005509=GO_REF:0000019, GO:0001778=GO_REF:0000019, GO:0030672=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0005764=GO_REF:0000019, GO:0008021=GO_REF:0000002} O43581 Synaptotagmin-7 protein 20130413 {GO:0017158=IEA, GO:0005215=IEA, GO:0030054=IEA, GO:0050796=IEA, GO:0005886=IEA, GO:0016020=IEA, GO:0005509=IEA, GO:0001778=IEA, GO:0030672=IEA, GO:0016021=IEA, GO:0005764=IEA, GO:0008021=IEA} plasma membrane repair, regulation of calcium ion-dependent exocytosis, regulation of insulin secretion cell junction, integral to membrane, lysosome, membrane, plasma membrane, synaptic vesicle, synaptic vesicle membrane calcium ion binding, transporter activity Human UniProtKB-SubCell:SL-0260 SYT8 UniProtKB UniProtKB {GO:0005215=GO_REF:0000002, GO:0005737=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0001669=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0031988=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007340=GO_REF:0000019, GO:0048306=GO_REF:0000019, GO:0008021=GO_REF:0000002} Q8NBV8 Synaptotagmin-8 protein 20130413 {GO:0005215=IEA, GO:0005737=IEA, GO:0005886=IEA, GO:0001669=IEA, GO:0016020=IEA, GO:0031988=IEA, GO:0016021=IEA, GO:0007340=IEA, GO:0048306=IEA, GO:0008021=IEA} acrosome reaction acrosomal vesicle, cytoplasm, integral to membrane, membrane, membrane-bounded vesicle, plasma membrane, synaptic vesicle calcium-dependent protein binding, transporter activity Human UniProtKB-SubCell:SL-0039 SYT9 UniProtKB UniProtKB {GO:0017158=GO_REF:0000019, GO:0005215=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0050796=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0031045=GO_REF:0000019, GO:0030672=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0042802=GO_REF:0000019, GO:0030667=GO_REF:0000019, GO:0008021=GO_REF:0000002} Q86SS6 Synaptotagmin-9 protein 20130413 {GO:0017158=IEA, GO:0005215=IEA, GO:0030054=IEA, GO:0050796=IEA, GO:0016020=IEA, GO:0031045=IEA, GO:0030672=IEA, GO:0016021=IEA, GO:0046872=IEA, GO:0042802=IEA, GO:0030667=IEA, GO:0008021=IEA} regulation of calcium ion-dependent exocytosis, regulation of insulin secretion cell junction, dense core granule, integral to membrane, membrane, secretory granule membrane, synaptic vesicle, synaptic vesicle membrane identical protein binding, metal ion binding, transporter activity Human UniProtKB-SubCell:SL-0260 SYTL1 UniProtKB UniProtKB {GO:0005515=PMID:18266782, GO:0042470=GO_REF:0000024, GO:0005215=GO_REF:0000002, GO:0017137=GO_REF:0000002, GO:0005886=PMID:18266782, GO:0016020=GO_REF:0000019, GO:0006887=PMID:18266782, GO:0042043=GO_REF:0000024, GO:0006886=GO_REF:0000002, GO:0019897=GO_REF:0000024, GO:0008021=GO_REF:0000002} Q8IYJ3 Synaptotagmin-like protein 1 protein 20090720 {GO:0005515=IPI, GO:0042470=ISS, GO:0005215=IEA, GO:0017137=IEA, GO:0005886=IDA, GO:0016020=IEA, GO:0006887=IDA, GO:0042043=ISS, GO:0006886=IEA, GO:0019897=ISS, GO:0008021=IEA} exocytosis, intracellular protein transport extrinsic to plasma membrane, melanosome, membrane, plasma membrane, synaptic vesicle Rab GTPase binding, neurexin family protein binding, protein binding, transporter activity Human UniProtKB:P51159 SYTL2 HPA UniProtKB {GO:0005515=PMID:18940603, GO:0005215=GO_REF:0000002, GO:0042470=GO_REF:0000024, GO:0017137=GO_REF:0000002, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0019902=PMID:19389623, GO:0005546=PMID:17182843, GO:0005634=GO_REF:0000052, GO:0006887=PMID:18812475, GO:0006886=GO_REF:0000002, GO:0042043=GO_REF:0000024, GO:0008021=GO_REF:0000002, GO:0006904=PMID:18812475, GO:0005737=GO_REF:0000052, GO:0016020=GO_REF:0000024, GO:0010923=PMID:19389623, GO:0001786=PMID:17182843, GO:0016192=GO_REF:0000024, GO:0019897=GO_REF:0000024, GO:0070382=PMID:18812475} Q9HCH5 Synaptotagmin-like protein 2 protein 20110516 {GO:0005515=IPI, GO:0005215=IEA, GO:0042470=ISS, GO:0017137=IEA, GO:0005794=IDA, GO:0005886=IDA, GO:0019902=IDA, GO:0005546=IMP, GO:0005634=IDA, GO:0006887=IDA, GO:0006886=IEA, GO:0042043=ISS, GO:0008021=IEA, GO:0006904=IDA, GO:0005737=IDA, GO:0016020=ISS, GO:0010923=IDA, GO:0001786=IMP, GO:0016192=ISS, GO:0019897=ISS, GO:0070382=IDA} exocytosis, intracellular protein transport, negative regulation of phosphatase activity, vesicle docking involved in exocytosis, vesicle-mediated transport Golgi apparatus, cytoplasm, exocytic vesicle, extrinsic to plasma membrane, melanosome, membrane, nucleus, plasma membrane, synaptic vesicle Rab GTPase binding, neurexin family protein binding, phosphatase binding, phosphatidylinositol-4,5-bisphosphate binding, phosphatidylserine binding, protein binding, transporter activity Human SYTL3 UniProtKB UniProtKB {GO:0005544=GO_REF:0000019, GO:0017137=GO_REF:0000002, GO:0042043=GO_REF:0000019, GO:0006886=GO_REF:0000002, GO:0019897=GO_REF:0000019, GO:0012505=GO_REF:0000039} Q4VX76 Synaptotagmin-like protein 3 protein 20130413 {GO:0005544=IEA, GO:0017137=IEA, GO:0042043=IEA, GO:0006886=IEA, GO:0019897=IEA, GO:0012505=IEA} intracellular protein transport endomembrane system, extrinsic to plasma membrane Rab GTPase binding, calcium-dependent phospholipid binding, neurexin family protein binding Human UniProtKB-SubCell:SL-0147 SYTL4 HPA UniProtKB {GO:0005215=GO_REF:0000002, GO:0017137=GO_REF:0000002, GO:0005813=GO_REF:0000052, GO:0005886=GO_REF:0000039, GO:0050714=PMID:19966785, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006887=GO_REF:0000019, GO:0042043=GO_REF:0000024, GO:0006886=GO_REF:0000002, GO:0008021=GO_REF:0000002, GO:0045921=PMID:19966785, GO:0005737=GO_REF:0000052, GO:0071985=PMID:19966785, GO:0005543=GO_REF:0000024, GO:0016020=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0030141=GO_REF:0000019, GO:0046676=GO_REF:0000019, GO:0005768=PMID:19966785, GO:0019898=GO_REF:0000024, GO:0030658=GO_REF:0000039} Q96C24 Synaptotagmin-like protein 4 protein 20080205 {GO:0005215=IEA, GO:0017137=IEA, GO:0005813=IDA, GO:0005886=IEA, GO:0050714=IMP, GO:0005730=IDA, GO:0005634=IDA, GO:0006887=IEA, GO:0042043=ISS, GO:0006886=IEA, GO:0008021=IEA, GO:0045921=IMP, GO:0005737=IDA, GO:0071985=IMP, GO:0005543=ISS, GO:0016020=IEA, GO:0008270=IEA, GO:0030141=IEA, GO:0046676=IEA, GO:0005768=IDA, GO:0019898=ISS, GO:0030658=IEA} exocytosis, intracellular protein transport, multivesicular body sorting pathway, negative regulation of insulin secretion, positive regulation of exocytosis, positive regulation of protein secretion centrosome, cytoplasm, endosome, extrinsic to membrane, membrane, nucleolus, nucleus, plasma membrane, secretory granule, synaptic vesicle, transport vesicle membrane Rab GTPase binding, neurexin family protein binding, phospholipid binding, transporter activity, zinc ion binding Human SYTL5 IntAct UniProtKB {GO:0005515=PMID:12051743, GO:0017137=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0006887=GO_REF:0000019, GO:0006886=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q8TDW5 Synaptotagmin-like protein 5 protein 20130415 {GO:0005515=IPI, GO:0017137=IEA, GO:0016020=IEA, GO:0006887=IEA, GO:0006886=IEA, GO:0046872=IEA} exocytosis, intracellular protein transport membrane Rab GTPase binding, metal ion binding, protein binding Human UniProtKB:Q9ERI2 SYVN1 HPA UniProtKB {GO:0005515=PMID:18264092, GO:0043066=GO_REF:0000019, GO:0016567=GO_REF:0000041, GO:0016881=PMID:12459480, GO:0005783=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0030433=PMID:22607976, GO:0001701=GO_REF:0000019, GO:0030968=Reactome:REACT_18356, GO:0005789=Reactome:REACT_115682, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0018279=PMID:22607976} Q86TM6 E3 ubiquitin-protein ligase synoviolin protein 20080205 {GO:0005515=IPI, GO:0043066=IEA, GO:0016567=IEA, GO:0016881=IDA, GO:0005783=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0030433=IMP, GO:0001701=IEA, GO:0030968=TAS, GO:0005789=TAS, GO:0008270=IEA, GO:0016021=IEA, GO:0006987=TAS, GO:0044267=TAS, GO:0018279=IMP} ER-associated protein catabolic process, activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, in utero embryonic development, negative regulation of apoptotic process, protein N-linked glycosylation via asparagine, protein ubiquitination endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, nucleolus, nucleus acid-amino acid ligase activity, protein binding, zinc ion binding Human SZT2 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0005777=GO_REF:0000039} Q5T011 Protein SZT2 protein 20120517 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND, GO:0005777=IEA} biological_process cellular_component, peroxisome molecular_function Human TAAR6 GDB UniProtKB {GO:0007186=PMID:15718104, GO:0005886=GO_REF:0000039, GO:0004930=PMID:15718104, GO:0016021=GO_REF:0000037, GO:0001594=GO_REF:0000002} Q96RI8 Trace amine-associated receptor 6 protein 20050816 {GO:0007186=TAS, GO:0005886=IEA, GO:0004930=TAS, GO:0016021=IEA, GO:0001594=IEA} G-protein coupled receptor signaling pathway integral to membrane, plasma membrane G-protein coupled receptor activity, trace-amine receptor activity Human TAB1 Reactome UniProtKB {GO:0005515=PMID:10094049, GO:0034142=Reactome:REACT_6894, GO:0030324=GO_REF:0000019, GO:0070423=Reactome:REACT_75776, GO:0007249=Reactome:REACT_25351, GO:0003824=GO_REF:0000002, GO:0051403=Reactome:REACT_21308, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_75887, GO:0002756=Reactome:REACT_6809, GO:0000187=Reactome:REACT_21399, GO:0051092=Reactome:REACT_21281, GO:0000185=GO_REF:0000019, GO:0002755=Reactome:REACT_27215, GO:0007179=GO_REF:0000019, GO:0034138=Reactome:REACT_6783, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0007254=Reactome:REACT_21368, GO:0002224=Reactome:REACT_9020, GO:0001701=GO_REF:0000019, GO:0019209=GO_REF:0000019, GO:0003007=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0034166=Reactome:REACT_9027, GO:0035666=Reactome:REACT_25281, GO:0008047=PMID:8638164, GO:0034146=Reactome:REACT_9061, GO:0010008=Reactome:REACT_25322, GO:0034162=Reactome:REACT_9047} Q15750 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 protein 20130213 {GO:0005515=IPI, GO:0034142=TAS, GO:0030324=IEA, GO:0070423=TAS, GO:0007249=TAS, GO:0003824=IEA, GO:0051403=TAS, GO:0035872=TAS, GO:0005829=TAS, GO:0002756=TAS, GO:0000187=TAS, GO:0051092=TAS, GO:0000185=IEA, GO:0002755=TAS, GO:0007179=IEA, GO:0034138=TAS, GO:0038124=TAS, GO:0038123=TAS, GO:0034134=TAS, GO:0007254=TAS, GO:0002224=TAS, GO:0001701=IEA, GO:0019209=IEA, GO:0003007=IEA, GO:0045087=TAS, GO:0034166=TAS, GO:0035666=TAS, GO:0008047=TAS, GO:0034146=TAS, GO:0010008=TAS, GO:0034162=TAS} I-kappaB kinase/NF-kappaB cascade, JNK cascade, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, activation of MAPK activity, activation of MAPKKK activity, heart morphogenesis, in utero embryonic development, innate immune response, lung development, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, nucleotide-binding oligomerization domain containing signaling pathway, positive regulation of NF-kappaB transcription factor activity, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, transforming growth factor beta receptor signaling pathway cytosol, endosome membrane catalytic activity, enzyme activator activity, kinase activator activity, protein binding Human TAB2 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0050852=Reactome:REACT_12526, GO:0034142=Reactome:REACT_6894, GO:0005886=Reactome:REACT_75887, GO:0070423=Reactome:REACT_75776, GO:0007249=Reactome:REACT_25351, GO:0051403=Reactome:REACT_21308, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_25288, GO:0007507=PMID:20493459, GO:0005622=GO_REF:0000002, GO:0002756=Reactome:REACT_6809, GO:0000187=Reactome:REACT_21399, GO:0051092=Reactome:REACT_21281, GO:0016301=GO_REF:0000038, GO:0002755=Reactome:REACT_27215, GO:0045860=PMID:11460167, GO:0043123=PMID:12761501, GO:0034138=Reactome:REACT_6783, GO:0070530=PMID:19935683, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0007254=Reactome:REACT_21368, GO:0002224=Reactome:REACT_9020, GO:0045087=Reactome:REACT_6802, GO:0034166=Reactome:REACT_9027, GO:0035666=Reactome:REACT_25281, GO:0008270=GO_REF:0000002, GO:0034146=Reactome:REACT_9061, GO:0010008=Reactome:REACT_25322, GO:0034162=Reactome:REACT_9047} Q9NYJ8 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 protein 20130415 {GO:0005515=IPI, GO:0050852=TAS, GO:0034142=TAS, GO:0005886=TAS, GO:0070423=TAS, GO:0007249=TAS, GO:0051403=TAS, GO:0035872=TAS, GO:0005829=TAS, GO:0007507=IMP, GO:0005622=IEA, GO:0002756=TAS, GO:0000187=TAS, GO:0051092=TAS, GO:0016301=IEA, GO:0002755=TAS, GO:0045860=IDA, GO:0043123=IEP, GO:0034138=TAS, GO:0070530=IDA, GO:0038124=TAS, GO:0038123=TAS, GO:0034134=TAS, GO:0007254=TAS, GO:0002224=TAS, GO:0045087=TAS, GO:0034166=TAS, GO:0035666=TAS, GO:0008270=IEA, GO:0034146=TAS, GO:0010008=TAS, GO:0034162=TAS} I-kappaB kinase/NF-kappaB cascade, JNK cascade, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, T cell receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, activation of MAPK activity, heart development, innate immune response, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, nucleotide-binding oligomerization domain containing signaling pathway, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of protein kinase activity, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway cytosol, endosome membrane, intracellular, plasma membrane K63-linked polyubiquitin binding, kinase activity, protein binding, zinc ion binding Human UniProtKB:Q05516 TAB3 IntAct UniProtKB {GO:0005515=PMID:17158449, GO:0034142=Reactome:REACT_6894, GO:0005886=Reactome:REACT_75887, GO:0007249=Reactome:REACT_25351, GO:0070423=Reactome:REACT_75776, GO:0051403=Reactome:REACT_21308, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_25288, GO:0002756=Reactome:REACT_6809, GO:0000187=Reactome:REACT_21399, GO:0051092=Reactome:REACT_21281, GO:0002755=Reactome:REACT_27215, GO:0034138=Reactome:REACT_6783, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0007254=Reactome:REACT_21368, GO:0002224=Reactome:REACT_9020, GO:0045087=Reactome:REACT_6802, GO:0035666=Reactome:REACT_25281, GO:0008270=GO_REF:0000002, GO:0034166=Reactome:REACT_9027, GO:0034146=Reactome:REACT_9061, GO:0010008=Reactome:REACT_25322, GO:0034162=Reactome:REACT_9047} Q8N5C8 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 protein 20130415 {GO:0005515=IPI, GO:0034142=TAS, GO:0005886=TAS, GO:0007249=TAS, GO:0070423=TAS, GO:0051403=TAS, GO:0035872=TAS, GO:0005829=TAS, GO:0002756=TAS, GO:0000187=TAS, GO:0051092=TAS, GO:0002755=TAS, GO:0034138=TAS, GO:0038124=TAS, GO:0038123=TAS, GO:0034134=TAS, GO:0007254=TAS, GO:0002224=TAS, GO:0045087=TAS, GO:0035666=TAS, GO:0008270=IEA, GO:0034166=TAS, GO:0034146=TAS, GO:0010008=TAS, GO:0034162=TAS} I-kappaB kinase/NF-kappaB cascade, JNK cascade, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, activation of MAPK activity, innate immune response, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, nucleotide-binding oligomerization domain containing signaling pathway, positive regulation of NF-kappaB transcription factor activity, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway cytosol, endosome membrane, plasma membrane protein binding, zinc ion binding Human UniProtKB:Q62073 TAC1 Reactome UniProtKB {GO:0030424=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0007267=PMID:1708336, GO:0007268=GO_REF:0000037, GO:2000854=GO_REF:0000019, GO:0007204=PMID:8957234, GO:0005615=GO_REF:0000019, GO:0006954=GO_REF:0000019, GO:0002675=GO_REF:0000019, GO:0007218=GO_REF:0000037, GO:0031835=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0045760=GO_REF:0000019, GO:0009725=GO_REF:0000019, GO:0010459=GO_REF:0000019, GO:0008306=GO_REF:0000019, GO:0007616=GO_REF:0000019, GO:0050671=GO_REF:0000019, GO:0007217=GO_REF:0000002, GO:0005576=Reactome:REACT_22436, GO:0043278=GO_REF:0000019, GO:0019233=GO_REF:0000019, GO:0032230=GO_REF:0000019, GO:0007320=PMID:1708336, GO:0032224=GO_REF:0000019, GO:0009582=PMID:9482938, GO:0046878=GO_REF:0000019, GO:0051496=GO_REF:0000019, GO:0035815=GO_REF:0000019, GO:0008217=GO_REF:0000019, GO:0048265=GO_REF:0000019, GO:0010634=GO_REF:0000019} P20366 Protachykinin-1 protein 20081126 {GO:0030424=IEA, GO:0005886=IEA, GO:0007267=TAS, GO:0007268=IEA, GO:2000854=IEA, GO:0007204=IDA, GO:0005615=IEA, GO:0006954=IEA, GO:0002675=IEA, GO:0007218=IEA, GO:0031835=IEA, GO:0032496=IEA, GO:0043025=IEA, GO:0045760=IEA, GO:0009725=IEA, GO:0010459=IEA, GO:0008306=IEA, GO:0007616=IEA, GO:0050671=IEA, GO:0007217=IEA, GO:0005576=TAS, GO:0043278=IEA, GO:0019233=IEA, GO:0032230=IEA, GO:0007320=TAS, GO:0032224=IEA, GO:0009582=TAS, GO:0046878=IEA, GO:0051496=IEA, GO:0035815=IEA, GO:0008217=IEA, GO:0048265=IEA, GO:0010634=IEA} associative learning, cell-cell signaling, detection of abiotic stimulus, elevation of cytosolic calcium ion concentration, inflammatory response, insemination, long-term memory, negative regulation of heart rate, neuropeptide signaling pathway, positive regulation of action potential, positive regulation of acute inflammatory response, positive regulation of corticosterone secretion, positive regulation of epithelial cell migration, positive regulation of lymphocyte proliferation, positive regulation of renal sodium excretion, positive regulation of saliva secretion, positive regulation of stress fiber assembly, positive regulation of synaptic transmission, GABAergic, positive regulation of synaptic transmission, cholinergic, regulation of blood pressure, response to hormone stimulus, response to lipopolysaccharide, response to morphine, response to pain, sensory perception of pain, synaptic transmission, tachykinin receptor signaling pathway axon, extracellular region, extracellular space, neuronal cell body, plasma membrane substance P receptor binding Human TAC3 Reactome UniProtKB {GO:0007565=PMID:10866201, GO:0007218=GO_REF:0000037, GO:0005102=PMID:10866201, GO:0007217=GO_REF:0000002, GO:0005576=Reactome:REACT_22436, GO:0005615=PMID:10866201} Q9UHF0 Tachykinin-3 protein 20081126 {GO:0007565=TAS, GO:0007218=IEA, GO:0005102=TAS, GO:0007217=IEA, GO:0005576=TAS, GO:0005615=TAS} female pregnancy, neuropeptide signaling pathway, tachykinin receptor signaling pathway extracellular region, extracellular space receptor binding Human TAC4 UniProtKB UniProtKB {GO:0046878=GO_REF:0000019, GO:0005102=GO_REF:0000019, GO:0008217=GO_REF:0000037, GO:0007217=GO_REF:0000019, GO:0005576=GO_REF:0000039} Q86UU9 Tachykinin-4 protein 20130413 {GO:0046878=IEA, GO:0005102=IEA, GO:0008217=IEA, GO:0007217=IEA, GO:0005576=IEA} positive regulation of saliva secretion, regulation of blood pressure, tachykinin receptor signaling pathway extracellular region receptor binding Human UniProtKB-SubCell:SL-0243 TACC1 HPA UniProtKB {GO:0005515=PMID:14603251, GO:0021987=GO_REF:0000019, GO:0005815=GO_REF:0000039, GO:0019904=GO_REF:0000019, GO:0000226=GO_REF:0000019, GO:0032886=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0007049=GO_REF:0000037, GO:0015630=GO_REF:0000052, GO:0022027=GO_REF:0000019, GO:0045111=GO_REF:0000052, GO:0022008=GO_REF:0000019, GO:0051301=GO_REF:0000037} O75410 Transforming acidic coiled-coil-containing protein 1 protein 20120912 {GO:0005515=IPI, GO:0021987=IEA, GO:0005815=IEA, GO:0019904=IEA, GO:0000226=IEA, GO:0032886=IEA, GO:0005634=IEA, GO:0005737=IDA, GO:0007049=IEA, GO:0015630=IDA, GO:0022027=IEA, GO:0045111=IDA, GO:0022008=IEA, GO:0051301=IEA} cell cycle, cell division, cerebral cortex development, interkinetic nuclear migration, microtubule cytoskeleton organization, neurogenesis, regulation of microtubule-based process cytoplasm, intermediate filament cytoskeleton, microtubule cytoskeleton, microtubule organizing center, nucleus protein binding, protein domain specific binding Human TACC2 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0021987=GO_REF:0000019, GO:0005794=GO_REF:0000052, GO:0005815=GO_REF:0000039, GO:0022027=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0035257=PMID:15207008, GO:0032886=GO_REF:0000019, GO:0030953=GO_REF:0000019, GO:0022008=GO_REF:0000019} O95359 Transforming acidic coiled-coil-containing protein 2 protein 20111111 {GO:0005737=IDA, GO:0021987=IEA, GO:0005794=IDA, GO:0005815=IEA, GO:0022027=IEA, GO:0019904=IEA, GO:0005730=IDA, GO:0035257=IDA, GO:0032886=IEA, GO:0030953=IEA, GO:0022008=IEA} astral microtubule organization, cerebral cortex development, interkinetic nuclear migration, neurogenesis, regulation of microtubule-based process Golgi apparatus, cytoplasm, microtubule organizing center, nucleolus nuclear hormone receptor binding, protein domain specific binding Human TACC3 HPA UniProtKB {GO:0030097=GO_REF:0000019, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0021987=GO_REF:0000019, GO:0022027=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0051726=GO_REF:0000019, GO:0006950=GO_REF:0000019, GO:0032886=GO_REF:0000019, GO:0030953=GO_REF:0000019, GO:0042994=GO_REF:0000019, GO:0022008=GO_REF:0000019} Q9Y6A5 Transforming acidic coiled-coil-containing protein 3 protein 20101115 {GO:0030097=IEA, GO:0005813=IDA, GO:0005737=IDA, GO:0021987=IEA, GO:0022027=IEA, GO:0019904=IEA, GO:0051726=IEA, GO:0006950=IEA, GO:0032886=IEA, GO:0030953=IEA, GO:0042994=IEA, GO:0022008=IEA} astral microtubule organization, cerebral cortex development, cytoplasmic sequestering of transcription factor, hemopoiesis, interkinetic nuclear migration, neurogenesis, regulation of cell cycle, regulation of microtubule-based process, response to stress centrosome, cytoplasm protein domain specific binding Human TACO1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0006417=GO_REF:0000037} Q9BSH4 Translational activator of cytochrome c oxidase 1 protein 20101115 {GO:0005739=IDA, GO:0006417=IEA} regulation of translation mitochondrion Human TACR1 BHF-UCL UniProtKB {GO:0005515=PMID:17986524, GO:0009408=GO_REF:0000019, GO:0010996=GO_REF:0000019, GO:0004995=PMID:8985172, GO:0070474=GO_REF:0000019, GO:0002118=GO_REF:0000019, GO:0046887=GO_REF:0000019, GO:0007610=PMID:9733503, GO:0045760=GO_REF:0000019, GO:0032355=GO_REF:0000019, GO:0008306=GO_REF:0000019, GO:0050679=GO_REF:0000019, GO:0002526=GO_REF:0000019, GO:0007616=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0010193=GO_REF:0000019, GO:0050671=GO_REF:0000019, GO:0007217=PMID:17986524, GO:0043278=GO_REF:0000019, GO:0032230=GO_REF:0000019, GO:0060083=GO_REF:0000019, GO:0032224=GO_REF:0000019, GO:0046878=GO_REF:0000019, GO:0005887=PMID:1657150, GO:0035815=GO_REF:0000019, GO:0016496=GO_REF:0000019, GO:0051496=GO_REF:0000019, GO:0032570=GO_REF:0000019, GO:0005886=PMID:17986524, GO:0045471=GO_REF:0000019, GO:0014910=GO_REF:0000019, GO:0007200=PMID:1657150, GO:0045777=GO_REF:0000019, GO:0007204=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0006954=PMID:10854844, GO:0045907=GO_REF:0000019, GO:0035106=GO_REF:0000019, GO:0048660=GO_REF:0000019, GO:0044297=GO_REF:0000019, GO:0042713=GO_REF:0000019, GO:0009582=PMID:9537323, GO:0002687=GO_REF:0000019, GO:0042755=GO_REF:0000019, GO:0007638=PMID:9537323, GO:0010634=GO_REF:0000019, GO:0048266=GO_REF:0000019, GO:0003051=GO_REF:0000019, GO:0043117=GO_REF:0000019, GO:0035094=GO_REF:0000019} P25103 Substance-P receptor protein 20080206 {GO:0005515=IPI, GO:0009408=IEA, GO:0010996=IEA, GO:0004995=TAS, GO:0070474=IEA, GO:0002118=IEA, GO:0046887=IEA, GO:0007610=TAS, GO:0045760=IEA, GO:0032355=IEA, GO:0008306=IEA, GO:0050679=IEA, GO:0002526=IEA, GO:0007616=IEA, GO:0009986=IEA, GO:0010193=IEA, GO:0050671=IEA, GO:0007217=IDA, GO:0043278=IEA, GO:0032230=IEA, GO:0060083=IEA, GO:0032224=IEA, GO:0046878=IEA, GO:0005887=TAS, GO:0035815=IEA, GO:0016496=IEA, GO:0051496=IEA, GO:0032570=IEA, GO:0005886=IDA, GO:0045471=IEA, GO:0014910=IEA, GO:0007200=TAS, GO:0045777=IEA, GO:0007204=IEA, GO:0030425=IEA, GO:0005737=IEA, GO:0006954=TAS, GO:0045907=IEA, GO:0035106=IEA, GO:0048660=IEA, GO:0044297=IEA, GO:0042713=IEA, GO:0009582=TAS, GO:0002687=IEA, GO:0042755=IEA, GO:0007638=TAS, GO:0010634=IEA, GO:0048266=IEA, GO:0003051=IEA, GO:0043117=IEA, GO:0035094=IEA} acute inflammatory response, aggressive behavior, angiotensin-mediated drinking behavior, associative learning, behavior, behavioral response to pain, detection of abiotic stimulus, eating behavior, elevation of cytosolic calcium ion concentration, inflammatory response, long-term memory, mechanosensory behavior, operant conditioning, phospholipase C-activating G-protein coupled receptor signaling pathway, positive regulation of action potential, positive regulation of blood pressure, positive regulation of epithelial cell migration, positive regulation of epithelial cell proliferation, positive regulation of hormone secretion, positive regulation of leukocyte migration, positive regulation of lymphocyte proliferation, positive regulation of renal sodium excretion, positive regulation of saliva secretion, positive regulation of stress fiber assembly, positive regulation of synaptic transmission, GABAergic, positive regulation of synaptic transmission, cholinergic, positive regulation of uterine smooth muscle contraction, positive regulation of vascular permeability, positive regulation of vasoconstriction, regulation of smooth muscle cell migration, regulation of smooth muscle cell proliferation, response to auditory stimulus, response to estradiol stimulus, response to ethanol, response to heat, response to morphine, response to nicotine, response to ozone, response to progesterone stimulus, smooth muscle contraction involved in micturition, sperm ejaculation, tachykinin receptor signaling pathway cell body, cell surface, cytoplasm, dendrite, integral to plasma membrane, plasma membrane protein binding, substance P receptor activity, tachykinin receptor activity Human UniProtKB:P34947 TACR2 Reactome UniProtKB {GO:0007588=PMID:10862829, GO:0005886=Reactome:REACT_22436, GO:0070459=GO_REF:0000019, GO:0033685=GO_REF:0000019, GO:0006950=GO_REF:0000019, GO:0007217=PMID:8307161, GO:0014057=GO_REF:0000019, GO:0014827=GO_REF:0000019, GO:0004995=PMID:8307161, GO:0006936=PMID:2173708, GO:0070474=GO_REF:0000019, GO:0005887=PMID:2173708, GO:0016497=GO_REF:0000019, GO:0016021=GO_REF:0000002, GO:0035106=GO_REF:0000019, GO:0043117=GO_REF:0000019} P21452 Substance-K receptor protein 20081126 {GO:0007588=TAS, GO:0005886=TAS, GO:0070459=IEA, GO:0033685=IEA, GO:0006950=IEA, GO:0007217=TAS, GO:0014057=IEA, GO:0014827=IEA, GO:0004995=TAS, GO:0006936=TAS, GO:0070474=IEA, GO:0005887=TAS, GO:0016497=IEA, GO:0016021=IEA, GO:0035106=IEA, GO:0043117=IEA} excretion, intestine smooth muscle contraction, muscle contraction, negative regulation of luteinizing hormone secretion, operant conditioning, positive regulation of acetylcholine secretion, positive regulation of uterine smooth muscle contraction, positive regulation of vascular permeability, prolactin secretion, response to stress, tachykinin receptor signaling pathway integral to membrane, integral to plasma membrane, plasma membrane substance K receptor activity, tachykinin receptor activity Human TACR3 Reactome UniProtKB {GO:0060259=GO_REF:0000019, GO:0005886=Reactome:REACT_22436, GO:0007568=GO_REF:0000019, GO:0007217=PMID:8990205, GO:0005634=GO_REF:0000019, GO:0042538=GO_REF:0000019, GO:0043278=GO_REF:0000019, GO:0042220=GO_REF:0000019, GO:0045777=GO_REF:0000019, GO:0042053=GO_REF:0000019, GO:0004995=GO_REF:0000019, GO:0070474=GO_REF:0000019, GO:0005887=PMID:1374246, GO:0010460=GO_REF:0000019, GO:0032355=GO_REF:0000019} P29371 Neuromedin-K receptor protein 20100524 {GO:0060259=IEA, GO:0005886=TAS, GO:0007568=IEA, GO:0007217=TAS, GO:0005634=IEA, GO:0042538=IEA, GO:0043278=IEA, GO:0042220=IEA, GO:0045777=IEA, GO:0042053=IEA, GO:0004995=IEA, GO:0070474=IEA, GO:0005887=TAS, GO:0010460=IEA, GO:0032355=IEA} aging, hyperosmotic salinity response, positive regulation of blood pressure, positive regulation of heart rate, positive regulation of uterine smooth muscle contraction, regulation of dopamine metabolic process, regulation of feeding behavior, response to cocaine, response to estradiol stimulus, response to morphine, tachykinin receptor signaling pathway integral to plasma membrane, nucleus, plasma membrane tachykinin receptor activity Human TACSTD2 PINC UniProtKB {GO:0050678=GO_REF:0000019, GO:0008283=PMID:7665234, GO:2000146=GO_REF:0000024, GO:0060675=GO_REF:0000019, GO:0016328=GO_REF:0000024, GO:0005829=PMID:10192395, GO:0051497=GO_REF:0000024, GO:1900028=GO_REF:0000024, GO:0009925=GO_REF:0000024, GO:0016020=PMID:8382772, GO:0005887=PMID:7665234, GO:1900025=GO_REF:0000024, GO:0090191=GO_REF:0000024, GO:0004872=PMID:7665234, GO:0007601=GO_REF:0000037, GO:0007166=PMID:7665234, GO:0010633=GO_REF:0000024} P09758 Tumor-associated calcium signal transducer 2 protein 20030904 {GO:0050678=IEA, GO:0008283=TAS, GO:2000146=ISS, GO:0060675=IEA, GO:0016328=ISS, GO:0005829=TAS, GO:0051497=ISS, GO:1900028=ISS, GO:0009925=ISS, GO:0016020=TAS, GO:0005887=TAS, GO:1900025=ISS, GO:0090191=ISS, GO:0004872=TAS, GO:0007601=IEA, GO:0007166=TAS, GO:0010633=ISS} cell proliferation, cell surface receptor signaling pathway, negative regulation of branching involved in ureteric bud morphogenesis, negative regulation of cell motility, negative regulation of epithelial cell migration, negative regulation of ruffle assembly, negative regulation of stress fiber assembly, negative regulation of substrate adhesion-dependent cell spreading, regulation of epithelial cell proliferation, ureteric bud morphogenesis, visual perception basal plasma membrane, cytosol, integral to plasma membrane, lateral plasma membrane, membrane receptor activity Human TADA1 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0043966=PMID:11564863, GO:0030914=PMID:11564863, GO:0003713=PMID:11564863, GO:0004402=PMID:11564863, GO:0006351=GO_REF:0000037} Q96BN2 Transcriptional adapter 1 protein 20090427 {GO:0006355=IEA, GO:0043966=IDA, GO:0030914=IDA, GO:0003713=IDA, GO:0004402=IDA, GO:0006351=IEA} histone H3 acetylation, regulation of transcription, DNA-dependent, transcription, DNA-dependent STAGA complex histone acetyltransferase activity, transcription coactivator activity Human TADA2A PINC UniProtKB {GO:0003712=PMID:8552087, GO:0072686=GO_REF:0000019, GO:0003700=PMID:8552087, GO:0006366=PMID:8552087, GO:0005694=GO_REF:0000039, GO:0005634=PMID:8552087, GO:0003677=GO_REF:0000037, GO:0007067=GO_REF:0000019, GO:0031647=GO_REF:0000019, GO:0043966=PMID:9674425, GO:0000125=PMID:9674425, GO:0003682=GO_REF:0000002, GO:0031063=GO_REF:0000019, GO:0005671=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0001932=GO_REF:0000019, GO:0090043=GO_REF:0000019, GO:0004402=PMID:9674425} O75478 Transcriptional adapter 2-alpha protein 20030904 {GO:0003712=TAS, GO:0072686=IEA, GO:0003700=TAS, GO:0006366=TAS, GO:0005694=IEA, GO:0005634=TAS, GO:0003677=IEA, GO:0007067=IEA, GO:0031647=IEA, GO:0043966=IDA, GO:0000125=IDA, GO:0003682=IEA, GO:0031063=IEA, GO:0005671=IEA, GO:0008270=IEA, GO:0001932=IEA, GO:0090043=IEA, GO:0004402=IDA} histone H3 acetylation, mitosis, regulation of histone deacetylation, regulation of protein phosphorylation, regulation of protein stability, regulation of tubulin deacetylation, transcription from RNA polymerase II promoter Ada2/Gcn5/Ada3 transcription activator complex, PCAF complex, chromosome, mitotic spindle, nucleus DNA binding, chromatin binding, histone acetyltransferase activity, sequence-specific DNA binding transcription factor activity, transcription cofactor activity, zinc ion binding Human TADA2B BHF-UCL UniProtKB {GO:0006355=GO_REF:0000037, GO:0030914=GO_REF:0000019, GO:0003682=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0070461=PMID:18838386} Q86TJ2 Transcriptional adapter 2-beta protein 20101105 {GO:0006355=IEA, GO:0030914=IEA, GO:0003682=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0070461=IDA} regulation of transcription, DNA-dependent, transcription, DNA-dependent SAGA-type complex, STAGA complex DNA binding, chromatin binding, zinc ion binding Human TADA3 HPA UniProtKB {GO:0005515=PMID:16189514, GO:0072686=GO_REF:0000019, GO:0003700=PMID:9674425, GO:0005634=GO_REF:0000052, GO:0005622=GO_REF:0000054, GO:0031647=GO_REF:0000019, GO:0030374=GO_REF:0000019, GO:0004402=PMID:11564863, GO:0016922=PMID:20413580, GO:0006357=PMID:9674425, GO:0030914=PMID:11564863, GO:0003713=PMID:20413580, GO:0019904=PMID:20413580, GO:0005730=GO_REF:0000052, GO:0006351=GO_REF:0000037, GO:0033276=PMID:10373431, GO:0010628=PMID:20413580, GO:0007067=GO_REF:0000019, GO:0043966=PMID:18838386, GO:0031063=GO_REF:0000019, GO:0005671=PMID:18838386, GO:0001932=GO_REF:0000019, GO:0090043=GO_REF:0000019, GO:0045893=PMID:20413580, GO:0030520=PMID:20413580} O75528 Transcriptional adapter 3 protein 20111111 {GO:0005515=IPI, GO:0072686=IEA, GO:0003700=TAS, GO:0005634=IDA, GO:0005622=IDA, GO:0031647=IEA, GO:0030374=IEA, GO:0004402=IDA, GO:0016922=IPI, GO:0006357=TAS, GO:0030914=IDA, GO:0003713=IDA, GO:0019904=IPI, GO:0005730=IDA, GO:0006351=IEA, GO:0033276=IDA, GO:0010628=IMP, GO:0007067=IEA, GO:0043966=IDA, GO:0031063=IEA, GO:0005671=IDA, GO:0001932=IEA, GO:0090043=IEA, GO:0045893=IDA, GO:0030520=TAS} histone H3 acetylation, intracellular estrogen receptor signaling pathway, mitosis, positive regulation of gene expression, positive regulation of transcription, DNA-dependent, regulation of histone deacetylation, regulation of protein phosphorylation, regulation of protein stability, regulation of transcription from RNA polymerase II promoter, regulation of tubulin deacetylation, transcription, DNA-dependent Ada2/Gcn5/Ada3 transcription activator complex, STAGA complex, intracellular, mitotic spindle, nucleolus, nucleus, transcription factor TFTC complex histone acetyltransferase activity, ligand-dependent nuclear receptor binding, ligand-dependent nuclear receptor transcription coactivator activity, protein binding, protein domain specific binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity NOT Human TAF1 GOC UniProtKB {GO:0005515=PMID:7590250, GO:0010467=Reactome:REACT_71, GO:0022415=Reactome:REACT_6361, GO:0006368=Reactome:REACT_2089, GO:0006367=Reactome:REACT_1851, GO:0006366=Reactome:REACT_1366, GO:0044212=GO_REF:0000024, GO:0032436=PMID:15053879, GO:0005634=GO_REF:0000052, GO:0060261=GO_REF:0000024, GO:0002039=PMID:15053879, GO:0046777=PMID:8625415, GO:0018105=PMID:8625415, GO:0045944=PMID:9660973, GO:0071339=PMID:15960975, GO:0018107=PMID:15053879, GO:0016032=Reactome:REACT_6256, GO:0070577=PMID:17996705, GO:0000080=PMID:9660973, GO:0004402=PMID:8980232, GO:0006352=GO_REF:0000024, GO:0005669=PMID:8625415, GO:0016573=PMID:8980232, GO:0003713=PMID:17996705, GO:0005730=GO_REF:0000052, GO:0005524=GO_REF:0000037, GO:0006974=PMID:15053879, GO:0000117=GO_REF:0000024, GO:0043565=GO_REF:0000024, GO:0004674=PMID:15053879, GO:0019048=GO_REF:0000037, GO:0017025=PMID:9660973, GO:0005654=Reactome:REACT_1844, GO:0051123=GO_REF:0000024, GO:0008134=PMID:8625415} P21675 Transcription initiation factor TFIID subunit 1 protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0022415=TAS, GO:0006368=TAS, GO:0006367=TAS, GO:0006366=TAS, GO:0044212=ISS, GO:0032436=IDA, GO:0005634=IDA, GO:0060261=ISS, GO:0002039=IPI, GO:0046777=IDA, GO:0018105=IDA, GO:0045944=IGI, GO:0071339=IDA, GO:0018107=IDA, GO:0016032=TAS, GO:0070577=IDA, GO:0000080=IGI, GO:0004402=IDA, GO:0006352=ISS, GO:0005669=IDA, GO:0016573=IDA, GO:0003713=IDA, GO:0005730=IDA, GO:0005524=IEA, GO:0006974=IC, GO:0000117=ISS, GO:0043565=ISS, GO:0004674=IDA, GO:0019048=IEA, GO:0017025=IPI, GO:0005654=TAS, GO:0051123=ISS, GO:0008134=IPI} DNA-dependent transcription, initiation, G1 phase of mitotic cell cycle, RNA polymerase II transcriptional preinitiation complex assembly, gene expression, histone acetylation, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription initiation from RNA polymerase II promoter, protein autophosphorylation, regulation of transcription involved in G2/M-phase of mitotic cell cycle, response to DNA damage stimulus, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, viral reproduction, viral reproductive process, virus-host interaction MLL1 complex, nucleolus, nucleoplasm, nucleus, transcription factor TFIID complex ATP binding, TBP-class protein binding, histone acetyl-lysine binding, histone acetyltransferase activity, p53 binding, protein binding, protein serine/threonine kinase activity, sequence-specific DNA binding, transcription coactivator activity, transcription factor binding, transcription regulatory region DNA binding Human TAF10 HPA UniProtKB {GO:0005515=PMID:16415881, GO:0010467=Reactome:REACT_71, GO:0022415=Reactome:REACT_6361, GO:0048471=PMID:15870280, GO:0006368=Reactome:REACT_2089, GO:0006367=Reactome:REACT_1851, GO:0003700=PMID:9603525, GO:0006366=Reactome:REACT_1366, GO:0005634=GO_REF:0000052, GO:0005737=PMID:15870280, GO:0000125=PMID:9674425, GO:0016032=Reactome:REACT_6256, GO:0051260=PMID:7923369, GO:0070063=PMID:15099517, GO:0004402=PMID:9674425, GO:0006352=PMID:9603525, GO:0016578=PMID:18206972, GO:0005669=PMID:14580349, GO:0030914=PMID:11564863, GO:0003713=PMID:11564863, GO:0030331=PMID:7923369, GO:0033276=PMID:9603525, GO:0043966=PMID:9674425, GO:0005654=Reactome:REACT_1844, GO:0019899=PMID:16415881} Q12962 Transcription initiation factor TFIID subunit 10 protein 20080818 {GO:0005515=IPI, GO:0010467=TAS, GO:0022415=TAS, GO:0048471=IDA, GO:0006368=TAS, GO:0006367=TAS, GO:0003700=IDA, GO:0006366=TAS, GO:0005634=IDA, GO:0005737=IDA, GO:0000125=IDA, GO:0016032=TAS, GO:0051260=IDA, GO:0070063=IDA, GO:0004402=IDA, GO:0006352=IDA, GO:0016578=IDA, GO:0005669=IDA, GO:0030914=IDA, GO:0003713=IDA, GO:0030331=IDA, GO:0033276=IDA, GO:0043966=IDA, GO:0005654=TAS, GO:0019899=IPI} DNA-dependent transcription, initiation, gene expression, histone H3 acetylation, histone deubiquitination, protein homooligomerization, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, viral reproduction, viral reproductive process PCAF complex, STAGA complex, cytoplasm, nucleoplasm, nucleus, perinuclear region of cytoplasm, transcription factor TFIID complex, transcription factor TFTC complex RNA polymerase binding, enzyme binding, estrogen receptor binding, histone acetyltransferase activity, protein binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity Human TAF11 IntAct UniProtKB {GO:0005515=PMID:9695952, GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006368=Reactome:REACT_2089, GO:0006355=GO_REF:0000037, GO:0006367=Reactome:REACT_1851, GO:0005669=PMID:14580349, GO:0046982=GO_REF:0000002, GO:0006366=Reactome:REACT_1366, GO:0003713=PMID:8670810, GO:0003677=GO_REF:0000019, GO:0043923=PMID:9108034, GO:0046966=PMID:10744685, GO:0047485=PMID:7729427, GO:0042809=PMID:10744685, GO:0016032=Reactome:REACT_6256, GO:0005654=Reactome:REACT_1844} Q15544 Transcription initiation factor TFIID subunit 11 protein 20130415 {GO:0005515=IPI, GO:0022415=TAS, GO:0010467=TAS, GO:0006368=TAS, GO:0006355=IEA, GO:0006367=TAS, GO:0005669=IDA, GO:0046982=IEA, GO:0006366=TAS, GO:0003713=IDA, GO:0003677=IEA, GO:0043923=IDA, GO:0046966=IPI, GO:0047485=IPI, GO:0042809=IPI, GO:0016032=TAS, GO:0005654=TAS} gene expression, positive regulation by host of viral transcription, regulation of transcription, DNA-dependent, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, viral reproduction, viral reproductive process nucleoplasm, transcription factor TFIID complex DNA binding, protein N-terminus binding, protein binding, protein heterodimerization activity, thyroid hormone receptor binding, transcription coactivator activity, vitamin D receptor binding Human UniProtKB:Q15543 TAF12 Reactome UniProtKB {GO:0005515=PMID:7729427, GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006352=PMID:9603525, GO:0006368=Reactome:REACT_2089, GO:0006367=Reactome:REACT_1851, GO:0003700=PMID:9603525, GO:0005669=PMID:14580349, GO:0046982=GO_REF:0000002, GO:0006366=Reactome:REACT_1366, GO:0030914=GO_REF:0000019, GO:0003677=PMID:15601843, GO:0033276=PMID:9603525, GO:0051091=PMID:15735663, GO:0016032=Reactome:REACT_6256, GO:0005654=Reactome:REACT_1844, GO:0008134=PMID:17264123} Q16514 Transcription initiation factor TFIID subunit 12 protein 20130213 {GO:0005515=IPI, GO:0022415=TAS, GO:0010467=TAS, GO:0006352=IDA, GO:0006368=TAS, GO:0006367=TAS, GO:0003700=IDA, GO:0005669=IDA, GO:0046982=IEA, GO:0006366=TAS, GO:0030914=IEA, GO:0003677=IDA, GO:0033276=IDA, GO:0051091=IDA, GO:0016032=TAS, GO:0005654=TAS, GO:0008134=IDA} DNA-dependent transcription, initiation, gene expression, positive regulation of sequence-specific DNA binding transcription factor activity, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, viral reproduction, viral reproductive process STAGA complex, nucleoplasm, transcription factor TFIID complex, transcription factor TFTC complex DNA binding, protein binding, protein heterodimerization activity, sequence-specific DNA binding transcription factor activity, transcription factor binding Human TAF13 HPA UniProtKB {GO:0005515=PMID:9695952, GO:0022415=Reactome:REACT_6361, GO:0006352=PMID:9695952, GO:0010467=Reactome:REACT_71, GO:0006368=Reactome:REACT_2089, GO:0003700=PMID:9695952, GO:0005669=PMID:7729427, GO:0006367=Reactome:REACT_1851, GO:0046982=GO_REF:0000002, GO:0006366=Reactome:REACT_1366, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008022=PMID:7729427, GO:0003677=GO_REF:0000019, GO:0016032=Reactome:REACT_6256, GO:0005654=Reactome:REACT_1844} Q15543 Transcription initiation factor TFIID subunit 13 protein 20111111 {GO:0005515=IPI, GO:0022415=TAS, GO:0006352=NAS, GO:0010467=TAS, GO:0006368=TAS, GO:0003700=NAS, GO:0005669=IDA, GO:0006367=TAS, GO:0046982=IEA, GO:0006366=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0008022=IPI, GO:0003677=IEA, GO:0016032=TAS, GO:0005654=TAS} DNA-dependent transcription, initiation, gene expression, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, viral reproduction, viral reproductive process nucleolus, nucleoplasm, nucleus, transcription factor TFIID complex DNA binding, protein C-terminus binding, protein binding, protein heterodimerization activity, sequence-specific DNA binding transcription factor activity Human TAF15 UniProtKB UniProtKB {GO:0005515=PMID:19124016, GO:0005622=GO_REF:0000002, GO:0005737=PMID:19124016, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005730=PMID:19124016, GO:0005634=PMID:19124016, GO:0008270=GO_REF:0000002, GO:0045893=PMID:19124016, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037} Q92804 TATA-binding protein-associated factor 2N protein 20110616 {GO:0005515=IPI, GO:0005622=IEA, GO:0005737=IDA, GO:0000166=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0045893=TAS, GO:0003676=IEA, GO:0003677=IEA} positive regulation of transcription, DNA-dependent cytoplasm, intracellular, nucleolus, nucleus DNA binding, RNA binding, nucleic acid binding, nucleotide binding, protein binding, zinc ion binding Human TAF1A Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000037, GO:0006366=PMID:7801123, GO:0006363=Reactome:REACT_1074, GO:0006362=Reactome:REACT_2204, GO:0006361=Reactome:REACT_1974, GO:0000120=GO_REF:0000002, GO:0006360=Reactome:REACT_1309, GO:0005654=Reactome:REACT_2228, GO:0003677=GO_REF:0000037} Q15573 TATA box-binding protein-associated factor RNA polymerase I subunit A protein 20130213 {GO:0010467=TAS, GO:0006355=IEA, GO:0006366=TAS, GO:0006363=TAS, GO:0006362=TAS, GO:0006361=TAS, GO:0000120=IEA, GO:0006360=TAS, GO:0005654=TAS, GO:0003677=IEA} gene expression, regulation of transcription, DNA-dependent, termination of RNA polymerase I transcription, transcription elongation from RNA polymerase I promoter, transcription from RNA polymerase I promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase I promoter RNA polymerase I transcription factor complex, nucleoplasm DNA binding Human TAF1B Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0001164=PMID:21921198, GO:0003700=PMID:7801123, GO:0006363=Reactome:REACT_1074, GO:0006362=Reactome:REACT_2204, GO:0006361=Reactome:REACT_1974, GO:0005634=PMID:7801123, GO:0006360=Reactome:REACT_1309, GO:0001187=PMID:21921198, GO:0046872=GO_REF:0000037, GO:0006351=PMID:7801123, GO:0001189=PMID:21921199, GO:0017025=PMID:21921199, GO:0005654=Reactome:REACT_2228, GO:0070860=PMID:21921198} Q53T94 TATA box-binding protein-associated factor RNA polymerase I subunit B protein 20130213 {GO:0010467=TAS, GO:0001164=IDA, GO:0003700=NAS, GO:0006363=TAS, GO:0006362=TAS, GO:0006361=TAS, GO:0005634=NAS, GO:0006360=TAS, GO:0001187=IDA, GO:0046872=IEA, GO:0006351=NAS, GO:0001189=IDA, GO:0017025=TAS, GO:0005654=TAS, GO:0070860=IDA} RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript, gene expression, termination of RNA polymerase I transcription, transcription elongation from RNA polymerase I promoter, transcription from RNA polymerase I promoter, transcription initiation from RNA polymerase I promoter, transcription, DNA-dependent RNA polymerase I core factor complex, nucleoplasm, nucleus RNA polymerase I CORE element sequence-specific DNA binding, RNA polymerase I CORE element sequence-specific DNA binding transcription factor recruiting transcription factor activity, TBP-class protein binding, metal ion binding, sequence-specific DNA binding transcription factor activity Human TAF1C Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000037, GO:0006366=PMID:7801123, GO:0006363=Reactome:REACT_1074, GO:0006362=Reactome:REACT_2204, GO:0006361=Reactome:REACT_1974, GO:0006360=Reactome:REACT_1309, GO:0005654=Reactome:REACT_2228, GO:0003677=GO_REF:0000037} Q15572 TATA box-binding protein-associated factor RNA polymerase I subunit C protein 20130213 {GO:0010467=TAS, GO:0006355=IEA, GO:0006366=TAS, GO:0006363=TAS, GO:0006362=TAS, GO:0006361=TAS, GO:0006360=TAS, GO:0005654=TAS, GO:0003677=IEA} gene expression, regulation of transcription, DNA-dependent, termination of RNA polymerase I transcription, transcription elongation from RNA polymerase I promoter, transcription from RNA polymerase I promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase I promoter nucleoplasm DNA binding Human TAF1D UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9H5J8 TATA box-binding protein-associated factor RNA polymerase I subunit D protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding Human UniProtKB-SubCell:SL-0191 TAF1L GOC UniProtKB {GO:0006352=GO_REF:0000002, GO:0005669=GO_REF:0000002, GO:0016573=PMID:12217962, GO:0006357=PMID:12217962, GO:0004674=PMID:12217962, GO:0017025=PMID:12217962, GO:0070577=PMID:22464331, GO:0005575=GO_REF:0000015, GO:0045893=PMID:12217962, GO:0003677=GO_REF:0000037, GO:0004402=PMID:12217962, GO:0007140=PMID:12217962} Q8IZX4 Transcription initiation factor TFIID subunit 1-like protein 20130413 {GO:0006352=IEA, GO:0005669=IEA, GO:0016573=ISS, GO:0006357=IDA, GO:0004674=ISS, GO:0017025=IPI, GO:0070577=IDA, GO:0005575=ND, GO:0045893=IDA, GO:0003677=IEA, GO:0004402=ISS, GO:0007140=IEP} DNA-dependent transcription, initiation, histone acetylation, male meiosis, positive regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter cellular_component, transcription factor TFIID complex DNA binding, TBP-class protein binding, histone acetyl-lysine binding, histone acetyltransferase activity, protein serine/threonine kinase activity Human UniProtKB:P21675 TAF2 MGI UniProtKB {GO:0005515=PMID:9418870, GO:0006367=PMID:9418870, GO:0005669=PMID:14580349, GO:0044212=PMID:10409744, GO:0045944=PMID:10409744, GO:0000086=PMID:10409744, GO:0008270=GO_REF:0000002, GO:0008237=GO_REF:0000002, GO:0033276=PMID:10373431} Q6P1X5 Transcription initiation factor TFIID subunit 2 protein 20091109 {GO:0005515=IPI, GO:0006367=IDA, GO:0005669=IDA, GO:0044212=IMP, GO:0045944=IMP, GO:0000086=IMP, GO:0008270=IEA, GO:0008237=IEA, GO:0033276=IDA} G2/M transition of mitotic cell cycle, positive regulation of transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter transcription factor TFIID complex, transcription factor TFTC complex metallopeptidase activity, protein binding, transcription regulatory region DNA binding, zinc ion binding Human TAF3 BHF-UCL UniProtKB {GO:0005515=PMID:15870280, GO:0002039=GO_REF:0000019, GO:0005669=PMID:11438666, GO:0051457=PMID:15870280, GO:0005634=PMID:15870280, GO:0008270=GO_REF:0000002, GO:0000122=PMID:18549481, GO:0043433=PMID:18549481, GO:0006351=GO_REF:0000037} Q5VWG9 Transcription initiation factor TFIID subunit 3 protein 20110428 {GO:0005515=IPI, GO:0002039=IEA, GO:0005669=IDA, GO:0051457=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0000122=IDA, GO:0043433=IDA, GO:0006351=IEA} maintenance of protein location in nucleus, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus, transcription factor TFIID complex p53 binding, protein binding, zinc ion binding Human TAF4 HPA UniProtKB {GO:0005515=PMID:7729427, GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006352=GO_REF:0000002, GO:0006368=Reactome:REACT_2089, GO:0006367=Reactome:REACT_1851, GO:0003700=GO_REF:0000002, GO:0005669=GO_REF:0000002, GO:0006366=Reactome:REACT_1366, GO:0046982=GO_REF:0000002, GO:0003713=PMID:9192867, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=PMID:15601843, GO:0033276=PMID:9603525, GO:0005737=GO_REF:0000052, GO:0001541=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0071339=PMID:15960975, GO:0016032=Reactome:REACT_6256, GO:0005654=Reactome:REACT_1844, GO:0045893=PMID:12771217} Q5TBP5 Transcription initiation factor TFIID subunit 4 protein 20080205 {GO:0005515=IPI, GO:0022415=TAS, GO:0010467=TAS, GO:0006352=IEA, GO:0006368=TAS, GO:0006367=TAS, GO:0003700=IEA, GO:0005669=IEA, GO:0006366=TAS, GO:0046982=IEA, GO:0003713=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IDA, GO:0033276=IDA, GO:0005737=IDA, GO:0001541=IEA, GO:0019048=IEA, GO:0071339=IDA, GO:0016032=TAS, GO:0005654=TAS, GO:0045893=IDA} DNA-dependent transcription, initiation, gene expression, ovarian follicle development, positive regulation of transcription, DNA-dependent, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, viral reproduction, viral reproductive process, virus-host interaction MLL1 complex, cytoplasm, nucleolus, nucleoplasm, nucleus, transcription factor TFIID complex, transcription factor TFTC complex DNA binding, protein binding, protein heterodimerization activity, sequence-specific DNA binding transcription factor activity, transcription coactivator activity Human TAF4B HPA UniProtKB {GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006352=GO_REF:0000029, GO:0006355=GO_REF:0000029, GO:0006368=Reactome:REACT_2089, GO:0003700=GO_REF:0000002, GO:0005669=GO_REF:0000002, GO:0006367=Reactome:REACT_1851, GO:0046982=GO_REF:0000002, GO:0051059=PMID:10849440, GO:0006366=Reactome:REACT_1366, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=PMID:15601843, GO:0005737=GO_REF:0000039, GO:0016032=Reactome:REACT_6256, GO:0005654=Reactome:REACT_1844} Q92750 Transcription initiation factor TFIID subunit 4B protein 20101115 {GO:0022415=TAS, GO:0010467=TAS, GO:0006352=NAS, GO:0006355=NAS, GO:0006368=TAS, GO:0003700=IEA, GO:0005669=IEA, GO:0006367=TAS, GO:0046982=IEA, GO:0051059=IPI, GO:0006366=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IDA, GO:0005737=IEA, GO:0016032=TAS, GO:0005654=TAS} DNA-dependent transcription, initiation, gene expression, regulation of transcription, DNA-dependent, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, viral reproduction, viral reproductive process cytoplasm, nucleolus, nucleoplasm, nucleus, transcription factor TFIID complex DNA binding, NF-kappaB binding, protein heterodimerization activity, sequence-specific DNA binding transcription factor activity NOT Human TAF5 GOC UniProtKB {GO:0005515=PMID:9045704, GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006352=PMID:9603525, GO:0006368=Reactome:REACT_2089, GO:0006367=Reactome:REACT_1851, GO:0005669=PMID:14580349, GO:0003700=PMID:9603525, GO:0016573=PMID:10373431, GO:0006366=Reactome:REACT_1366, GO:0044212=PMID:17996705, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0015629=GO_REF:0000052, GO:0043231=GO_REF:0000052, GO:0033276=PMID:9603525, GO:0019048=GO_REF:0000037, GO:0046983=PMID:17227857, GO:0016032=Reactome:REACT_6256, GO:0005654=Reactome:REACT_653, GO:0004402=PMID:10373431, GO:0016568=PMID:10373431} Q15542 Transcription initiation factor TFIID subunit 5 protein 20130413 {GO:0005515=IPI, GO:0022415=TAS, GO:0010467=TAS, GO:0006352=IDA, GO:0006368=TAS, GO:0006367=TAS, GO:0005669=IDA, GO:0003700=IDA, GO:0016573=IDA, GO:0006366=TAS, GO:0044212=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0015629=IDA, GO:0043231=IDA, GO:0033276=IDA, GO:0019048=IEA, GO:0046983=IDA, GO:0016032=TAS, GO:0005654=TAS, GO:0004402=IDA, GO:0016568=IC} DNA-dependent transcription, initiation, chromatin modification, gene expression, histone acetylation, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, viral reproduction, viral reproductive process, virus-host interaction actin cytoskeleton, intracellular membrane-bounded organelle, nucleolus, nucleoplasm, nucleus, transcription factor TFIID complex, transcription factor TFTC complex histone acetyltransferase activity, protein binding, protein dimerization activity, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding Human TAF5L PINC UniProtKB {GO:0003700=PMID:9674425, GO:0006366=PMID:9674425, GO:0043966=PMID:11564863, GO:0030914=PMID:11564863, GO:0003713=PMID:11564863, GO:0004402=PMID:11564863, GO:0033276=PMID:10373431} O75529 TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L protein 20030904 {GO:0003700=TAS, GO:0006366=TAS, GO:0043966=IDA, GO:0030914=IDA, GO:0003713=IDA, GO:0004402=IDA, GO:0033276=IDA} histone H3 acetylation, transcription from RNA polymerase II promoter STAGA complex, transcription factor TFTC complex histone acetyltransferase activity, sequence-specific DNA binding transcription factor activity, transcription coactivator activity Human TAF6 HPA UniProtKB {GO:0005515=PMID:9045704, GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006352=PMID:9603525, GO:0006368=Reactome:REACT_2089, GO:0005669=PMID:14580349, GO:0006367=Reactome:REACT_1851, GO:0003700=PMID:9603525, GO:0046982=GO_REF:0000002, GO:0006366=Reactome:REACT_1366, GO:0005634=GO_REF:0000052, GO:0045786=PMID:15328371, GO:0003677=PMID:15601843, GO:0033276=PMID:9603525, GO:0051090=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0071339=PMID:15960975, GO:0016032=Reactome:REACT_6256, GO:0005654=Reactome:REACT_1844} P49848 Transcription initiation factor TFIID subunit 6 protein 20080205 {GO:0005515=IPI, GO:0022415=TAS, GO:0010467=TAS, GO:0006352=IDA, GO:0006368=TAS, GO:0005669=IDA, GO:0006367=TAS, GO:0003700=IDA, GO:0046982=IEA, GO:0006366=TAS, GO:0005634=IDA, GO:0045786=IDA, GO:0003677=IDA, GO:0033276=IDA, GO:0051090=IEA, GO:0005737=IDA, GO:0071339=IDA, GO:0016032=TAS, GO:0005654=TAS} DNA-dependent transcription, initiation, gene expression, negative regulation of cell cycle, regulation of sequence-specific DNA binding transcription factor activity, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, viral reproduction, viral reproductive process MLL1 complex, cytoplasm, nucleoplasm, nucleus, transcription factor TFIID complex, transcription factor TFTC complex DNA binding, protein binding, protein heterodimerization activity, sequence-specific DNA binding transcription factor activity Human TAF6L IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0006352=GO_REF:0000002, GO:0046982=GO_REF:0000002, GO:0006357=PMID:9674425, GO:0030914=PMID:11564863, GO:0003713=PMID:11564863, GO:0005634=GO_REF:0000002, GO:0003677=PMID:9674425, GO:0051090=GO_REF:0000002, GO:0000118=PMID:9674425, GO:0043966=PMID:11564863, GO:0006338=PMID:9674425, GO:0004402=PMID:11564863} Q9Y6J9 TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L protein 20130415 {GO:0005515=IPI, GO:0006352=IEA, GO:0046982=IEA, GO:0006357=TAS, GO:0030914=IDA, GO:0003713=IDA, GO:0005634=IEA, GO:0003677=TAS, GO:0051090=IEA, GO:0000118=TAS, GO:0043966=IDA, GO:0006338=TAS, GO:0004402=IDA} DNA-dependent transcription, initiation, chromatin remodeling, histone H3 acetylation, regulation of sequence-specific DNA binding transcription factor activity, regulation of transcription from RNA polymerase II promoter STAGA complex, histone deacetylase complex, nucleus DNA binding, histone acetyltransferase activity, protein binding, protein heterodimerization activity, transcription coactivator activity Human UniProtKB:Q16594 TAF7 HPA UniProtKB {GO:0005515=PMID:7824954, GO:0000296=GO_REF:0000024, GO:0006367=PMID:9603525, GO:0003700=PMID:9603525, GO:0044212=PMID:18391197, GO:0006366=PMID:7824954, GO:0005634=GO_REF:0000052, GO:0035067=PMID:11592977, GO:0046966=PMID:10409738, GO:0042809=PMID:10409738, GO:0045944=PMID:12676957, GO:0071339=PMID:15960975, GO:0035035=PMID:11592977, GO:0006352=PMID:9603525, GO:0008024=PMID:18391197, GO:0005669=PMID:14580349, GO:0005794=GO_REF:0000052, GO:0003713=PMID:7824954, GO:0005730=GO_REF:0000052, GO:0000122=PMID:11592977, GO:0033276=PMID:9603525, GO:0006469=PMID:18391197, GO:0045892=PMID:18391197, GO:0008134=PMID:7824954, GO:0030520=GO_REF:0000019} Q15545 Transcription initiation factor TFIID subunit 7 protein 20101115 {GO:0005515=IPI, GO:0000296=ISS, GO:0006367=IDA, GO:0003700=IDA, GO:0044212=IDA, GO:0006366=IDA, GO:0005634=IDA, GO:0035067=IDA, GO:0046966=IPI, GO:0042809=IPI, GO:0045944=IDA, GO:0071339=IDA, GO:0035035=IPI, GO:0006352=IDA, GO:0008024=IDA, GO:0005669=IDA, GO:0005794=IDA, GO:0003713=IDA, GO:0005730=IDA, GO:0000122=IDA, GO:0033276=IDA, GO:0006469=IDA, GO:0045892=IDA, GO:0008134=IPI, GO:0030520=IEA} DNA-dependent transcription, initiation, intracellular estrogen receptor signaling pathway, negative regulation of histone acetylation, negative regulation of protein kinase activity, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of transcription from RNA polymerase II promoter, spermine transport, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter Golgi apparatus, MLL1 complex, nucleolus, nucleus, positive transcription elongation factor complex b, transcription factor TFIID complex, transcription factor TFTC complex histone acetyltransferase binding, protein binding, sequence-specific DNA binding transcription factor activity, thyroid hormone receptor binding, transcription coactivator activity, transcription factor binding, transcription regulatory region DNA binding, vitamin D receptor binding Human TAF7L UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000039, GO:0006355=GO_REF:0000037, GO:0006367=GO_REF:0000002, GO:0005669=GO_REF:0000002, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q5H9L4 Transcription initiation factor TFIID subunit 7-like protein 20090430 {GO:0003674=ND, GO:0008150=ND, GO:0005737=IEA, GO:0006355=IEA, GO:0006367=IEA, GO:0005669=IEA, GO:0007275=IEA, GO:0007283=IEA, GO:0030154=IEA} biological_process, cell differentiation, multicellular organismal development, regulation of transcription, DNA-dependent, spermatogenesis, transcription initiation from RNA polymerase II promoter cytoplasm, transcription factor TFIID complex molecular_function Human TAF8 HPA UniProtKB {GO:0005515=PMID:15870280, GO:0048471=PMID:15870280, GO:0005669=PMID:14580349, GO:0046982=GO_REF:0000002, GO:0051457=PMID:15870280, GO:0045598=PMID:14580349, GO:0001833=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0045893=PMID:14580349, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q7Z7C8 Transcription initiation factor TFIID subunit 8 protein 20120912 {GO:0005515=IPI, GO:0048471=IDA, GO:0005669=IDA, GO:0046982=IEA, GO:0051457=IDA, GO:0045598=IDA, GO:0001833=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0045893=IDA, GO:0030154=IEA, GO:0006351=IEA} cell differentiation, inner cell mass cell proliferation, maintenance of protein location in nucleus, positive regulation of transcription, DNA-dependent, regulation of fat cell differentiation, transcription, DNA-dependent nucleolus, nucleus, perinuclear region of cytoplasm, transcription factor TFIID complex protein binding, protein heterodimerization activity NOT Human TAF9 UniProtKB UniProtKB {GO:0005515=PMID:15489227, GO:0010467=Reactome:REACT_71, GO:0022415=Reactome:REACT_6361, GO:0006368=Reactome:REACT_2089, GO:0015030=PMID:16079131, GO:0006367=Reactome:REACT_1851, GO:0044212=PMID:19251649, GO:0006366=Reactome:REACT_1366, GO:0030307=PMID:15899866, GO:0005634=GO_REF:0000019, GO:0004017=PMID:15630091, GO:0032435=PMID:11278372, GO:0002039=PMID:11278372, GO:0000125=PMID:9674425, GO:0045944=PMID:11278372, GO:0071339=PMID:15960975, GO:0016032=Reactome:REACT_6256, GO:0033613=PMID:9171108, GO:0070555=PMID:15489227, GO:0004402=PMID:9674425, GO:0006352=GO_REF:0000002, GO:0043066=PMID:15899866, GO:0005669=PMID:14580349, GO:0046982=GO_REF:0000002, GO:0030914=PMID:11564863, GO:0060760=PMID:15489227, GO:0003713=PMID:11278372, GO:0005730=PMID:16079131, GO:0070761=PMID:17636026, GO:0005524=GO_REF:0000037, GO:0003677=PMID:15601843, GO:0006974=PMID:11278372, GO:0033276=PMID:15899866, GO:0043966=PMID:9674425, GO:0070742=PMID:19251649, GO:0005654=PMID:16079131} Q9Y3D8 Adenylate kinase isoenzyme 6 protein 20110125 {GO:0005515=IPI, GO:0010467=TAS, GO:0022415=TAS, GO:0006368=TAS, GO:0015030=IDA, GO:0006367=TAS, GO:0044212=IDA, GO:0006366=TAS, GO:0030307=IMP, GO:0005634=IEA, GO:0004017=IDA, GO:0032435=IDA, GO:0002039=IPI, GO:0000125=IDA, GO:0045944=IDA, GO:0071339=IDA, GO:0016032=TAS, GO:0033613=IPI, GO:0070555=IMP, GO:0004402=IDA, GO:0006352=IEA, GO:0043066=IMP, GO:0005669=IDA, GO:0046982=IEA, GO:0030914=IDA, GO:0060760=IMP, GO:0003713=IMP, GO:0005730=IDA, GO:0070761=IDA, GO:0005524=IEA, GO:0003677=IDA, GO:0006974=IC, GO:0033276=IDA, GO:0043966=IDA, GO:0070742=IPI, GO:0005654=IDA} DNA-dependent transcription, initiation, gene expression, histone H3 acetylation, negative regulation of apoptotic process, negative regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of cell growth, positive regulation of response to cytokine stimulus, positive regulation of transcription from RNA polymerase II promoter, response to DNA damage stimulus, response to interleukin-1, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, viral reproduction, viral reproductive process Cajal body, MLL1 complex, PCAF complex, STAGA complex, nucleolus, nucleoplasm, nucleus, pre-snoRNP complex, transcription factor TFIID complex, transcription factor TFTC complex ATP binding, C2H2 zinc finger domain binding, DNA binding, activating transcription factor binding, adenylate kinase activity, histone acetyltransferase activity, p53 binding, protein binding, protein heterodimerization activity, transcription coactivator activity, transcription regulatory region DNA binding Human TAF9B BHF-UCL UniProtKB {GO:0005515=PMID:15899866, GO:0014070=GO_REF:0000019, GO:0006352=GO_REF:0000002, GO:0043066=PMID:12837753, GO:0005669=PMID:15899866, GO:0046982=GO_REF:0000002, GO:0030307=PMID:15899866, GO:0003714=PMID:12837753, GO:0000122=PMID:12837753, GO:0012501=GO_REF:0000019, GO:0033276=PMID:15899866} Q9HBM6 Transcription initiation factor TFIID subunit 9B protein 20110607 {GO:0005515=IPI, GO:0014070=IEA, GO:0006352=IEA, GO:0043066=IMP, GO:0005669=IDA, GO:0046982=IEA, GO:0030307=IMP, GO:0003714=IC, GO:0000122=IMP, GO:0012501=IEA, GO:0033276=IDA} DNA-dependent transcription, initiation, negative regulation of apoptotic process, negative regulation of transcription from RNA polymerase II promoter, positive regulation of cell growth, programmed cell death, response to organic cyclic compound transcription factor TFIID complex, transcription factor TFTC complex protein binding, protein heterodimerization activity, transcription corepressor activity Human GO:0000122 TAGAP Reactome UniProtKB {GO:0005085=GO_REF:0000037, GO:0051056=Reactome:REACT_11051, GO:0007264=Reactome:REACT_11044, GO:0005829=Reactome:REACT_9982} Q8N103 T-cell activation Rho GTPase-activating protein protein 20130301 {GO:0005085=IEA, GO:0051056=TAS, GO:0007264=TAS, GO:0005829=TAS} regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cytosol guanyl-nucleotide exchange factor activity Human TAGLN UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0007517=GO_REF:0000002, GO:0003779=GO_REF:0000037} Q01995 Transgelin protein 20130413 {GO:0005737=IEA, GO:0007517=IEA, GO:0003779=IEA} muscle organ development cytoplasm actin binding Human UniProtKB-SubCell:SL-0086 TAGLN2 IntAct UniProtKB {GO:0005515=PMID:21577206, GO:0007517=GO_REF:0000002} P37802 Transgelin-2 protein 20130415 {GO:0005515=IPI, GO:0007517=IEA} muscle organ development protein binding Human UniProtKB:P60709 TAGLN3 PINC UniProtKB {GO:0007517=GO_REF:0000002, GO:0005634=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0007417=PMID:8015377} Q9UI15 Transgelin-3 protein 20030904 {GO:0007517=IEA, GO:0005634=IEA, GO:0000122=IEA, GO:0007417=TAS} central nervous system development, muscle organ development, negative regulation of transcription from RNA polymerase II promoter nucleus Human TAL1 BHF-UCL UniProtKB {GO:0005515=PMID:19497860, GO:0000790=PMID:20855495, GO:0003700=PMID:19497860, GO:0042826=PMID:19497860, GO:0044212=GO_REF:0000024, GO:0000981=GO_REF:0000019, GO:0045799=PMID:20855495, GO:0005634=PMID:19497860, GO:0031334=PMID:20855495, GO:0043249=GO_REF:0000019, GO:0060375=GO_REF:0000019, GO:0045944=PMID:20855495, GO:0042127=GO_REF:0000019, GO:0001085=PMID:15920471, GO:0046983=GO_REF:0000002, GO:0051781=PMID:20855495, GO:0007626=GO_REF:0000019, GO:0030221=PMID:7678994, GO:0035162=GO_REF:0000024, GO:0033193=PMID:19497860, GO:0030220=GO_REF:0000019, GO:0030097=GO_REF:0000024, GO:0005667=PMID:15920471, GO:0006357=GO_REF:0000024, GO:0046982=GO_REF:0000019, GO:0070888=PMID:20855495, GO:0060216=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0001525=GO_REF:0000019, GO:0060218=GO_REF:0000019, GO:0060217=GO_REF:0000019, GO:0021527=GO_REF:0000019, GO:2000036=GO_REF:0000019, GO:0045931=PMID:20855495, GO:0035855=GO_REF:0000019, GO:0000118=PMID:19497860, GO:0045165=GO_REF:0000024, GO:0060018=GO_REF:0000019, GO:0045648=GO_REF:0000024, GO:0030219=PMID:7678994, GO:0003682=PMID:16763211, GO:0030218=PMID:7678994, GO:0000980=GO_REF:0000019, GO:0019899=PMID:19497860, GO:0045893=PMID:20028976} P17542 T-cell acute lymphocytic leukemia protein 1 protein 20110810 {GO:0005515=IPI, GO:0000790=IDA, GO:0003700=IDA, GO:0042826=IPI, GO:0044212=ISS, GO:0000981=IEA, GO:0045799=IMP, GO:0005634=IDA, GO:0031334=IDA, GO:0043249=IEA, GO:0060375=IEA, GO:0045944=IDA, GO:0042127=IEA, GO:0001085=IPI, GO:0046983=IEA, GO:0051781=IMP, GO:0007626=IEA, GO:0030221=IEP, GO:0035162=ISS, GO:0033193=IDA, GO:0030220=IEA, GO:0030097=ISS, GO:0005667=IDA, GO:0006357=ISS, GO:0046982=IEA, GO:0070888=IDA, GO:0060216=IEA, GO:0000122=IEA, GO:0001525=IEA, GO:0060218=IEA, GO:0060217=IEA, GO:0021527=IEA, GO:2000036=IEA, GO:0045931=IMP, GO:0035855=IEA, GO:0000118=IDA, GO:0045165=ISS, GO:0060018=IEA, GO:0045648=ISS, GO:0030219=IEP, GO:0003682=IDA, GO:0030218=IEP, GO:0000980=IEA, GO:0019899=IPI, GO:0045893=IDA} angiogenesis, astrocyte fate commitment, basophil differentiation, cell fate commitment, definitive hemopoiesis, embryonic hemopoiesis, erythrocyte differentiation, erythrocyte maturation, hemangioblast cell differentiation, hematopoietic stem cell differentiation, hemopoiesis, locomotory behavior, megakaryocyte development, megakaryocyte differentiation, negative regulation of transcription from RNA polymerase II promoter, platelet formation, positive regulation of cell division, positive regulation of chromatin assembly or disassembly, positive regulation of erythrocyte differentiation, positive regulation of mitotic cell cycle, positive regulation of protein complex assembly, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of cell proliferation, regulation of mast cell differentiation, regulation of stem cell maintenance, regulation of transcription from RNA polymerase II promoter, spinal cord association neuron differentiation Lsd1/2 complex, histone deacetylase complex, nuclear chromatin, nucleus, transcription factor complex E-box binding, RNA polymerase II distal enhancer sequence-specific DNA binding, RNA polymerase II transcription factor binding, chromatin binding, enzyme binding, histone deacetylase binding, protein binding, protein dimerization activity, protein heterodimerization activity, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding Human UniProtKB:Q8IX07 TAL2 ENSEMBL UniProtKB {GO:0021794=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0035264=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0007610=GO_REF:0000019, GO:0030901=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q16559 T-cell acute lymphocytic leukemia protein 2 protein 20130413 {GO:0021794=IEA, GO:0006355=IEA, GO:0035264=IEA, GO:0046983=IEA, GO:0007610=IEA, GO:0030901=IEA, GO:0009791=IEA, GO:0003677=IEA, GO:0006351=IEA} behavior, midbrain development, multicellular organism growth, post-embryonic development, regulation of transcription, DNA-dependent, thalamus development, transcription, DNA-dependent DNA binding, protein dimerization activity Human Ensembl:ENSMUSP00000030124 TALDO1 Reactome UniProtKB {GO:0005737=PMID:16130169, GO:0006112=Reactome:REACT_1505, GO:0005999=Reactome:REACT_939, GO:0005975=Reactome:REACT_474, GO:0004801=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0006098=Reactome:REACT_1859, GO:0003824=GO_REF:0000002, GO:0005829=Reactome:REACT_1272} P37837 Transaldolase protein 20130301 {GO:0005737=TAS, GO:0006112=TAS, GO:0005999=TAS, GO:0005975=TAS, GO:0004801=IEA, GO:0044281=TAS, GO:0006098=TAS, GO:0003824=IEA, GO:0005829=TAS} carbohydrate metabolic process, energy reserve metabolic process, pentose-phosphate shunt, small molecule metabolic process, xylulose biosynthetic process cytoplasm, cytosol catalytic activity, sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Human TANC1 UniProtKB UniProtKB {GO:0097062=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000037, GO:0008542=GO_REF:0000019, GO:0045211=GO_REF:0000037, GO:0043025=GO_REF:0000019, GO:0014069=GO_REF:0000039, GO:0043679=GO_REF:0000019, GO:0007520=GO_REF:0000019} Q9C0D5 Protein TANC1 protein 20130413 {GO:0097062=IEA, GO:0030054=IEA, GO:0005886=IEA, GO:0008542=IEA, GO:0045211=IEA, GO:0043025=IEA, GO:0014069=IEA, GO:0043679=IEA, GO:0007520=IEA} dendritic spine maintenance, myoblast fusion, visual learning axon terminus, cell junction, neuronal cell body, plasma membrane, postsynaptic density, postsynaptic membrane Human UniProtKB-SubCell:SL-0297 TANK IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0007165=PMID:8710854, GO:0045087=Reactome:REACT_6802, GO:0007249=GO_REF:0000019, GO:0031625=PMID:11279055, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_25327} Q92844 TRAF family member-associated NF-kappa-B activator protein 20130415 {GO:0005515=IPI, GO:0007165=TAS, GO:0045087=TAS, GO:0007249=IEA, GO:0031625=IPI, GO:0046872=IEA, GO:0005829=TAS} I-kappaB kinase/NF-kappaB cascade, innate immune response, signal transduction cytosol metal ion binding, protein binding, ubiquitin protein ligase binding Human UniProtKB:Q9UHD2 TAOK1 Reactome UniProtKB {GO:0000236=Reactome:REACT_682, GO:0031577=PMID:20162290, GO:0031572=PMID:17396146, GO:0046330=PMID:16407310, GO:0006915=PMID:16407310, GO:0032874=PMID:17396146, GO:0005524=PMID:14517247, GO:0006974=PMID:17396146, GO:0005829=Reactome:REACT_150414, GO:0004672=PMID:14517247, GO:0006281=GO_REF:0000037, GO:0051493=GO_REF:0000024, GO:0004674=PMID:14517247, GO:0016301=PMID:14517247, GO:0000087=Reactome:REACT_910, GO:0006468=PMID:14517247, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0016740=PMID:14517247} Q7L7X3 Serine/threonine-protein kinase TAO1 protein 20130213 {GO:0000236=TAS, GO:0031577=IDA, GO:0031572=IMP, GO:0046330=IDA, GO:0006915=IDA, GO:0032874=IMP, GO:0005524=NAS, GO:0006974=IDA, GO:0005829=TAS, GO:0004672=NAS, GO:0006281=IEA, GO:0051493=ISS, GO:0004674=NAS, GO:0016301=NAS, GO:0000087=TAS, GO:0006468=NAS, GO:0000278=TAS, GO:0000090=TAS, GO:0016740=NAS} DNA repair, G2 DNA damage checkpoint, M phase of mitotic cell cycle, apoptotic process, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, positive regulation of JNK cascade, positive regulation of stress-activated MAPK cascade, protein phosphorylation, regulation of cytoskeleton organization, response to DNA damage stimulus, spindle checkpoint cytosol ATP binding, kinase activity, protein kinase activity, protein serine/threonine kinase activity, transferase activity Human TAOK2 HPA UniProtKB {GO:0030036=PMID:10660600, GO:0008360=PMID:10660600, GO:0031572=PMID:17396146, GO:0046330=PMID:10660600, GO:0032874=PMID:17396146, GO:0005634=GO_REF:0000052, GO:0001558=PMID:10660600, GO:0051403=PMID:11279118, GO:0030425=GO_REF:0000039, GO:0000186=PMID:10660600, GO:0005737=GO_REF:0000052, GO:0048041=PMID:10660600, GO:0006612=PMID:10660600, GO:0005856=GO_REF:0000039, GO:0030659=GO_REF:0000039, GO:0006950=PMID:10660600, GO:0005730=GO_REF:0000052, GO:0006915=PMID:10660600, GO:0031434=PMID:11279118, GO:0005524=GO_REF:0000037, GO:0006974=PMID:17396146, GO:0016477=PMID:10660600, GO:0004674=PMID:11279118, GO:0016023=PMID:10660600, GO:0016021=GO_REF:0000037} Q9UL54 Serine/threonine-protein kinase TAO2 protein 20080205 {GO:0030036=IDA, GO:0008360=IDA, GO:0031572=IMP, GO:0046330=IDA, GO:0032874=IMP, GO:0005634=IDA, GO:0001558=NAS, GO:0051403=IDA, GO:0030425=IEA, GO:0000186=IDA, GO:0005737=IDA, GO:0048041=IDA, GO:0006612=NAS, GO:0005856=IEA, GO:0030659=IEA, GO:0006950=IDA, GO:0005730=IDA, GO:0006915=NAS, GO:0031434=IPI, GO:0005524=IEA, GO:0006974=IDA, GO:0016477=NAS, GO:0004674=IDA, GO:0016023=IDA, GO:0016021=IEA} G2 DNA damage checkpoint, actin cytoskeleton organization, activation of MAPKK activity, apoptotic process, cell migration, focal adhesion assembly, positive regulation of JNK cascade, positive regulation of stress-activated MAPK cascade, protein targeting to membrane, regulation of cell growth, regulation of cell shape, response to DNA damage stimulus, response to stress, stress-activated MAPK cascade cytoplasm, cytoplasmic membrane-bounded vesicle, cytoplasmic vesicle membrane, cytoskeleton, dendrite, integral to membrane, nucleolus, nucleus ATP binding, mitogen-activated protein kinase kinase binding, protein serine/threonine kinase activity Human TAOK3 GOC UniProtKB {GO:0005515=PMID:11278723, GO:0005886=GO_REF:0000039, GO:0031572=PMID:17396146, GO:0046330=PMID:10924369, GO:0032874=PMID:17396146, GO:0005524=GO_REF:0000037, GO:0006974=PMID:17396146, GO:0005739=GO_REF:0000052, GO:0046329=PMID:10559204, GO:0004672=GO_REF:0000002, GO:0006281=GO_REF:0000037, GO:0046777=PMID:10559204, GO:0004674=PMID:10559204, GO:0000165=PMID:10924369, GO:0016301=GO_REF:0000038, GO:0004860=PMID:10559204, GO:0006468=PMID:10559204, GO:0006469=PMID:10559204, GO:0016740=PMID:10559204} Q9H2K8 Serine/threonine-protein kinase TAO3 protein 20130413 {GO:0005515=IPI, GO:0005886=IEA, GO:0031572=IMP, GO:0046330=IMP, GO:0032874=IMP, GO:0005524=IEA, GO:0006974=IDA, GO:0005739=IDA, GO:0046329=IDA, GO:0004672=IEA, GO:0006281=IEA, GO:0046777=IDA, GO:0004674=IDA, GO:0000165=IMP, GO:0016301=IEA, GO:0004860=TAS, GO:0006468=IDA, GO:0006469=TAS, GO:0016740=IDA} DNA repair, G2 DNA damage checkpoint, MAPK cascade, negative regulation of JNK cascade, negative regulation of protein kinase activity, positive regulation of JNK cascade, positive regulation of stress-activated MAPK cascade, protein autophosphorylation, protein phosphorylation, response to DNA damage stimulus mitochondrion, plasma membrane ATP binding, kinase activity, protein binding, protein kinase activity, protein kinase inhibitor activity, protein serine/threonine kinase activity, transferase activity Human TAP1 IntAct UniProtKB {GO:0005515=PMID:17055437, GO:0002474=Reactome:REACT_75820, GO:0042288=GO_REF:0000033, GO:0042825=PMID:15518576, GO:0005886=GO_REF:0000033, GO:0005743=GO_REF:0000033, GO:0042626=GO_REF:0000002, GO:0030176=PMID:7673167, GO:0042803=GO_REF:0000024, GO:0005829=PMID:11133832, GO:0005739=GO_REF:0000019, GO:0015833=PMID:11133832, GO:0046967=PMID:7538543, GO:0019885=PMID:11133832, GO:0042605=PMID:11133832, GO:0015197=PMID:7673167, GO:0015421=GO_REF:0000033, GO:0019060=PMID:7538543, GO:0046980=GO_REF:0000033, GO:0042590=Reactome:REACT_111119, GO:0006952=GO_REF:0000019, GO:0005524=PMID:7673167, GO:0055085=GO_REF:0000033, GO:0043531=PMID:11532960, GO:0001916=GO_REF:0000033, GO:0005789=Reactome:REACT_75922, GO:0002479=Reactome:REACT_111178, GO:0016021=PMID:8955196, GO:0046978=GO_REF:0000024, GO:0046979=PMID:11133832} Q03518 Antigen peptide transporter 1 protein 20130415 {GO:0005515=IPI, GO:0002474=TAS, GO:0042288=IBA, GO:0042825=IDA, GO:0005886=IBA, GO:0005743=IRD, GO:0042626=IEA, GO:0030176=IDA, GO:0042803=ISS, GO:0005829=NAS, GO:0005739=IEA, GO:0015833=IMP, GO:0046967=IMP, GO:0019885=IMP, GO:0042605=NAS, GO:0015197=IGI, GO:0015421=IBA, GO:0019060=IMP, GO:0046980=IBA, GO:0042590=TAS, GO:0006952=IEA, GO:0005524=IDA, GO:0055085=IBA, GO:0043531=IDA, GO:0001916=IBA, GO:0005789=TAS, GO:0002479=TAS, GO:0016021=IDA, GO:0046978=ISS, GO:0046979=IPI} antigen processing and presentation of endogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, cytosol to ER transport, defense response, intracellular transport of viral proteins in host cell, peptide transport, positive regulation of T cell mediated cytotoxicity, transmembrane transport TAP complex, cytosol, endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane, integral to membrane, mitochondrial inner membrane, mitochondrion, plasma membrane ADP binding, ATP binding, ATPase activity, coupled to transmembrane movement of substances, MHC class I protein binding, TAP1 binding, TAP2 binding, oligopeptide-transporting ATPase activity, peptide antigen binding, peptide transporter activity, protein binding, protein homodimerization activity, tapasin binding Human UniProtKB:Q03519 TAP2 HPA UniProtKB {GO:0005515=PMID:17055437, GO:0002474=Reactome:REACT_75820, GO:0005215=PMID:10835348, GO:0042288=GO_REF:0000033, GO:0042825=PMID:17947644, GO:0005886=GO_REF:0000033, GO:0005783=GO_REF:0000052, GO:0005743=GO_REF:0000033, GO:0042626=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0030176=PMID:7673167, GO:0002591=GO_REF:0000033, GO:0046968=PMID:1538751, GO:0015833=GO_REF:0000033, GO:0046967=PMID:7538543, GO:0019885=PMID:1538751, GO:0042605=GO_REF:0000033, GO:0002489=PMID:1538751, GO:0015197=PMID:7673167, GO:0015421=GO_REF:0000033, GO:0002481=GO_REF:0000033, GO:0019060=PMID:7538543, GO:0046980=GO_REF:0000024, GO:0002485=GO_REF:0000033, GO:0042590=Reactome:REACT_111119, GO:0005524=PMID:7673167, GO:0055085=GO_REF:0000033, GO:0001916=GO_REF:0000033, GO:0005789=Reactome:REACT_75922, GO:0002479=Reactome:REACT_111178, GO:0016021=PMID:8955196, GO:0015433=PMID:1538751, GO:0046978=PMID:15518576, GO:0046979=GO_REF:0000033} Q03519 Antigen peptide transporter 2 protein 20080818 {GO:0005515=IPI, GO:0002474=TAS, GO:0005215=IDA, GO:0042288=IBA, GO:0042825=IDA, GO:0005886=IBA, GO:0005783=IDA, GO:0005743=IRD, GO:0042626=IEA, GO:0005634=IDA, GO:0030176=IDA, GO:0002591=IBA, GO:0046968=IMP, GO:0015833=IBA, GO:0046967=IMP, GO:0019885=IMP, GO:0042605=IBA, GO:0002489=IMP, GO:0015197=IGI, GO:0015421=IBA, GO:0002481=IBA, GO:0019060=IMP, GO:0046980=ISS, GO:0002485=IBA, GO:0042590=TAS, GO:0005524=IDA, GO:0055085=IBA, GO:0001916=IBA, GO:0005789=TAS, GO:0002479=TAS, GO:0016021=IDA, GO:0015433=IMP, GO:0046978=IPI, GO:0046979=IBA} antigen processing and presentation of endogenous peptide antigen via MHC class I, antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent, antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, cytosol to ER transport, intracellular transport of viral proteins in host cell, peptide antigen transport, peptide transport, positive regulation of T cell mediated cytotoxicity, positive regulation of antigen processing and presentation of peptide antigen via MHC class I, transmembrane transport TAP complex, endoplasmic reticulum, endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane, integral to membrane, mitochondrial inner membrane, nucleus, plasma membrane ATP binding, ATPase activity, coupled to transmembrane movement of substances, MHC class I protein binding, TAP1 binding, TAP2 binding, oligopeptide-transporting ATPase activity, peptide antigen binding, peptide antigen-transporting ATPase activity, peptide transporter activity, protein binding, tapasin binding, transporter activity Human TAPBP InterPro UniProtKB {GO:0005515=PMID:17055437, GO:0002474=Reactome:REACT_75820, GO:0042824=PMID:12788224, GO:0042825=PMID:17947644, GO:0042288=PMID:12788224, GO:0005783=PMID:9238042, GO:0006890=PMID:11884415, GO:0042590=Reactome:REACT_111119, GO:0006952=GO_REF:0000019, GO:0050823=GO_REF:0000024, GO:0006955=PMID:9271576, GO:0006461=PMID:9271576, GO:0016020=GO_REF:0000002, GO:0000139=PMID:11884415, GO:0019885=GO_REF:0000002, GO:0042605=PMID:12788224, GO:0005789=PMID:11884415, GO:0071556=Reactome:REACT_75922, GO:0002479=Reactome:REACT_111178, GO:0015433=PMID:9238042, GO:0016021=PMID:9238042, GO:0051082=PMID:12788224, GO:0046978=PMID:12047747, GO:0046979=PMID:12047747} Q5HYV0 Tapasin protein 20130413 {GO:0005515=IPI, GO:0002474=TAS, GO:0042824=NAS, GO:0042825=IDA, GO:0042288=TAS, GO:0005783=TAS, GO:0006890=NAS, GO:0042590=TAS, GO:0006952=IEA, GO:0050823=ISS, GO:0006955=TAS, GO:0006461=TAS, GO:0016020=IEA, GO:0000139=IDA, GO:0019885=IEA, GO:0042605=TAS, GO:0005789=IDA, GO:0071556=TAS, GO:0002479=TAS, GO:0015433=TAS, GO:0016021=TAS, GO:0051082=TAS, GO:0046978=IPI, GO:0046979=IPI} antigen processing and presentation of endogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, defense response, immune response, peptide antigen stabilization, protein complex assembly, retrograde vesicle-mediated transport, Golgi to ER Golgi membrane, MHC class I peptide loading complex, TAP complex, endoplasmic reticulum, endoplasmic reticulum membrane, integral to lumenal side of endoplasmic reticulum membrane, integral to membrane, membrane MHC class I protein binding, TAP1 binding, TAP2 binding, peptide antigen binding, peptide antigen-transporting ATPase activity, protein binding, unfolded protein binding Human InterPro:IPR008056 TAPT1 UniProtKB UniProtKB {GO:0048706=GO_REF:0000019, GO:0016520=PMID:10640539, GO:0016021=PMID:10640539, GO:0009791=GO_REF:0000019, GO:0001701=GO_REF:0000019} Q6NXT6 Transmembrane anterior posterior transformation protein 1 homolog protein 20090811 {GO:0048706=IEA, GO:0016520=TAS, GO:0016021=TAS, GO:0009791=IEA, GO:0001701=IEA} embryonic skeletal system development, in utero embryonic development, post-embryonic development integral to membrane growth hormone-releasing hormone receptor activity Human TARBP1 PINC UniProtKB {GO:0006396=GO_REF:0000002, GO:0006357=PMID:8846792, GO:0003723=GO_REF:0000037, GO:0005634=PMID:8846792, GO:0008173=GO_REF:0000002} Q13395 Probable methyltransferase TARBP1 protein 20030904 {GO:0006396=IEA, GO:0006357=TAS, GO:0003723=IEA, GO:0005634=TAS, GO:0008173=IEA} RNA processing, regulation of transcription from RNA polymerase II promoter nucleus RNA binding, RNA methyltransferase activity Human TARBP2 HPA UniProtKB {GO:0003725=GO_REF:0000002, GO:0005515=PMID:21903422, GO:0030423=PMID:15973356, GO:0010467=Reactome:REACT_71, GO:0006355=PMID:8723388, GO:0048471=GO_REF:0000039, GO:0050689=PMID:11641396, GO:0030422=PMID:17452327, GO:0006357=PMID:2011739, GO:0005634=GO_REF:0000052, GO:0046782=PMID:11641396, GO:0006417=GO_REF:0000037, GO:0042803=PMID:17452327, GO:0005829=Reactome:REACT_118784, GO:0016442=PMID:15973356, GO:0005737=PMID:17452327, GO:0035197=PMID:15973356, GO:0031054=PMID:15973356, GO:0035280=PMID:15973356, GO:0006469=PMID:11641396, GO:0045070=PMID:11641396} Q15633 RISC-loading complex subunit TARBP2 protein 20120912 {GO:0003725=IEA, GO:0005515=IPI, GO:0030423=IMP, GO:0010467=TAS, GO:0006355=TAS, GO:0048471=IEA, GO:0050689=IDA, GO:0030422=IDA, GO:0006357=TAS, GO:0005634=IDA, GO:0046782=IDA, GO:0006417=IEA, GO:0042803=IPI, GO:0005829=TAS, GO:0016442=IDA, GO:0005737=IDA, GO:0035197=IDA, GO:0031054=IDA, GO:0035280=IDA, GO:0006469=TAS, GO:0045070=IDA} gene expression, miRNA loading onto RISC involved in gene silencing by miRNA, negative regulation of defense response to virus by host, negative regulation of protein kinase activity, positive regulation of viral genome replication, pre-miRNA processing, production of siRNA involved in RNA interference, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, regulation of translation, regulation of viral transcription, targeting of mRNA for destruction involved in RNA interference RNA-induced silencing complex, cytoplasm, cytosol, nucleus, perinuclear region of cytoplasm double-stranded RNA binding, protein binding, protein homodimerization activity, siRNA binding Human TARDBP HPA UniProtKB {GO:0006397=GO_REF:0000037, GO:0005515=PMID:21903422, GO:0008380=PMID:11285240, GO:0008219=GO_REF:0000037, GO:0003700=PMID:7745706, GO:0006366=PMID:7745706, GO:0003723=PMID:11285240, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000038, GO:0043922=PMID:7745706, GO:0003690=PMID:7745706, GO:0000166=GO_REF:0000002, GO:0003730=PMID:17481916, GO:0070935=PMID:17481916} Q13148 TAR DNA-binding protein 43 protein 20090616 {GO:0006397=IEA, GO:0005515=IPI, GO:0008380=IDA, GO:0008219=IEA, GO:0003700=TAS, GO:0006366=TAS, GO:0003723=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0003677=IEA, GO:0043922=IDA, GO:0003690=IDA, GO:0000166=IEA, GO:0003730=IDA, GO:0070935=IDA} 3'-UTR-mediated mRNA stabilization, RNA splicing, cell death, mRNA processing, negative regulation by host of viral transcription, transcription from RNA polymerase II promoter nucleolus, nucleus DNA binding, RNA binding, double-stranded DNA binding, mRNA 3'-UTR binding, nucleic acid binding, nucleotide binding, protein binding, sequence-specific DNA binding transcription factor activity NOT Human TARS HPA UniProtKB {GO:0010467=Reactome:REACT_71, GO:0006435=PMID:2033077, GO:0005737=GO_REF:0000052, GO:0004829=Reactome:REACT_15487, GO:0015629=GO_REF:0000052, GO:0006412=PMID:2033077, GO:0005524=GO_REF:0000037, GO:0042803=PMID:2033077, GO:0006418=Reactome:REACT_15482, GO:0005829=Reactome:REACT_15487} P26639 Threonine--tRNA ligase, cytoplasmic protein 20110516 {GO:0010467=TAS, GO:0006435=NAS, GO:0005737=IDA, GO:0004829=TAS, GO:0015629=IDA, GO:0006412=NAS, GO:0005524=IEA, GO:0042803=NAS, GO:0006418=TAS, GO:0005829=TAS} gene expression, tRNA aminoacylation for protein translation, threonyl-tRNA aminoacylation, translation actin cytoskeleton, cytoplasm, cytosol ATP binding, protein homodimerization activity, threonine-tRNA ligase activity Human TARS2 InterPro UniProtKB {GO:0003674=GO_REF:0000015, GO:0010467=Reactome:REACT_71, GO:0006435=GO_REF:0000002, GO:0005737=GO_REF:0000002, GO:0005759=GO_REF:0000039, GO:0004829=GO_REF:0000002, GO:0070159=PMID:15779907, GO:0005575=GO_REF:0000015, GO:0005524=GO_REF:0000002, GO:0004812=GO_REF:0000038, GO:0006418=Reactome:REACT_15482} Q9H9V2 cDNA FLJ12528 fis, clone NT2RM4000155, moderately similar to THREONYL-TRNA SYNTHETASE, CYTOPLASMIC (EC 6.1.1.3) protein 20130413 {GO:0003674=ND, GO:0010467=TAS, GO:0006435=IEA, GO:0005737=IEA, GO:0005759=IEA, GO:0004829=IEA, GO:0070159=TAS, GO:0005575=ND, GO:0005524=IEA, GO:0004812=IEA, GO:0006418=TAS} gene expression, mitochondrial threonyl-tRNA aminoacylation, tRNA aminoacylation for protein translation, threonyl-tRNA aminoacylation cellular_component, cytoplasm, mitochondrial matrix ATP binding, aminoacyl-tRNA ligase activity, molecular_function, threonine-tRNA ligase activity Human InterPro:IPR002320 TARSL2 InterPro UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0006435=GO_REF:0000002, GO:0005737=GO_REF:0000002, GO:0004829=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0043039=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0016876=GO_REF:0000002} H0YKB9 Probable threonine--tRNA ligase 2, cytoplasmic protein 20130413 {GO:0008150=ND, GO:0003674=ND, GO:0006435=IEA, GO:0005737=IEA, GO:0004829=IEA, GO:0005575=ND, GO:0043039=IEA, GO:0005524=IEA, GO:0016876=IEA} biological_process, tRNA aminoacylation, threonyl-tRNA aminoacylation cellular_component, cytoplasm ATP binding, ligase activity, forming aminoacyl-tRNA and related compounds, molecular_function, threonine-tRNA ligase activity Human InterPro:IPR012947 TAS1R1 GOC UniProtKB {GO:0050912=PMID:11917125, GO:0005886=Reactome:REACT_21256, GO:0046982=PMID:11917125, GO:0004930=GO_REF:0000002, GO:0008527=PMID:11917125, GO:0016021=PMID:11917125, GO:0050917=PMID:11917125} Q7RTX1 Taste receptor type 1 member 1 protein 20130413 {GO:0050912=IDA, GO:0005886=TAS, GO:0046982=NAS, GO:0004930=IEA, GO:0008527=IDA, GO:0016021=IC, GO:0050917=IDA} detection of chemical stimulus involved in sensory perception of taste, sensory perception of umami taste integral to membrane, plasma membrane G-protein coupled receptor activity, protein heterodimerization activity, taste receptor activity Human TAS1R2 Reactome UniProtKB {GO:0005886=Reactome:REACT_21366, GO:0007186=PMID:16720576, GO:0046982=PMID:11917125, GO:0001582=PMID:16720576, GO:0008527=PMID:16720576, GO:0033041=PMID:16720576, GO:0016021=PMID:11917125, GO:0050916=PMID:11917125} Q8TE23 Taste receptor type 1 member 2 protein 20091026 {GO:0005886=TAS, GO:0007186=IC, GO:0046982=NAS, GO:0001582=IDA, GO:0008527=IDA, GO:0033041=IDA, GO:0016021=IC, GO:0050916=IDA} G-protein coupled receptor signaling pathway, detection of chemical stimulus involved in sensory perception of sweet taste, sensory perception of sweet taste integral to membrane, plasma membrane protein heterodimerization activity, sweet taste receptor activity, taste receptor activity Human TAS1R3 Reactome UniProtKB {GO:0005886=Reactome:REACT_21366, GO:0007186=PMID:16720576, GO:0046982=PMID:11917125, GO:0001582=PMID:16720576, GO:0008527=PMID:16720576, GO:0033041=PMID:16720576, GO:0016021=PMID:11917125, GO:0050916=PMID:15299024, GO:0050917=PMID:11917125} Q7RTX0 Taste receptor type 1 member 3 protein 20091026 {GO:0005886=TAS, GO:0007186=IC, GO:0046982=NAS, GO:0001582=IDA, GO:0008527=IDA, GO:0033041=IDA, GO:0016021=IC, GO:0050916=IDA, GO:0050917=IDA} G-protein coupled receptor signaling pathway, detection of chemical stimulus involved in sensory perception of sweet taste, sensory perception of sweet taste, sensory perception of umami taste integral to membrane, plasma membrane protein heterodimerization activity, sweet taste receptor activity, taste receptor activity Human TAS2R13 GOC UniProtKB {GO:0050912=PMID:10761934, GO:0008150=GO_REF:0000015, GO:0008527=PMID:10761934, GO:0016021=GO_REF:0000029} Q9NYV9 Taste receptor type 2 member 13 protein 20130413 {GO:0050912=TAS, GO:0008150=ND, GO:0008527=TAS, GO:0016021=NAS} biological_process, detection of chemical stimulus involved in sensory perception of taste integral to membrane taste receptor activity Human TASP1 UniProtKB UniProtKB {GO:0016787=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0045893=PMID:14636557, GO:0004298=PMID:14636557} Q9H6P5 Threonine aspartase 1 protein 20091215 {GO:0016787=IEA, GO:0006508=IEA, GO:0045893=IMP, GO:0004298=IMP} positive regulation of transcription, DNA-dependent, proteolysis hydrolase activity, threonine-type endopeptidase activity Human TAT Reactome UniProtKB {GO:0006559=Reactome:REACT_1786, GO:0006536=PMID:7999802, GO:0009058=GO_REF:0000002, GO:0004838=Reactome:REACT_21382, GO:0051384=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0005575=GO_REF:0000015, GO:0005829=Reactome:REACT_21382, GO:0005739=GO_REF:0000019, GO:0034641=Reactome:REACT_13, GO:0030170=GO_REF:0000002, GO:0006103=PMID:7999802, GO:0006572=PMID:7999802, GO:0006979=GO_REF:0000019, GO:0016597=GO_REF:0000019, GO:0046689=GO_REF:0000019, GO:0080130=GO_REF:0000003} P17735 Tyrosine aminotransferase protein 20130213 {GO:0006559=TAS, GO:0006536=IDA, GO:0009058=IEA, GO:0004838=TAS, GO:0051384=IEA, GO:0044281=TAS, GO:0005575=ND, GO:0005829=TAS, GO:0005739=IEA, GO:0034641=TAS, GO:0030170=IEA, GO:0006103=IDA, GO:0006572=IDA, GO:0006979=IEA, GO:0016597=IEA, GO:0046689=IEA, GO:0080130=IEA} 2-oxoglutarate metabolic process, L-phenylalanine catabolic process, biosynthetic process, cellular nitrogen compound metabolic process, glutamate metabolic process, response to glucocorticoid stimulus, response to mercury ion, response to oxidative stress, small molecule metabolic process, tyrosine catabolic process cellular_component, cytosol, mitochondrion L-phenylalanine:2-oxoglutarate aminotransferase activity, L-tyrosine:2-oxoglutarate aminotransferase activity, amino acid binding, pyridoxal phosphate binding Human TATDN1 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039, GO:0016888=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q6P1N9 Putative deoxyribonuclease TATDN1 protein 20130413 {GO:0005634=IEA, GO:0016888=IEA, GO:0046872=IEA} nucleus endodeoxyribonuclease activity, producing 5'-phosphomonoesters, metal ion binding Human UniProtKB-SubCell:SL-0191 TATDN2 Reactome UniProtKB {GO:0005654=Reactome:REACT_115723, GO:0006987=Reactome:REACT_18368, GO:0016888=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0046872=GO_REF:0000037, GO:0030968=Reactome:REACT_18356} Q93075 Putative deoxyribonuclease TATDN2 protein 20130301 {GO:0005654=TAS, GO:0006987=TAS, GO:0016888=IEA, GO:0044267=TAS, GO:0046872=IEA, GO:0030968=TAS} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response nucleoplasm endodeoxyribonuclease activity, producing 5'-phosphomonoesters, metal ion binding Human TAX1BP1 BHF-UCL UniProtKB {GO:0005515=PMID:15474016, GO:0043066=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0006915=GO_REF:0000037, GO:0032088=GO_REF:0000024, GO:0019900=GO_REF:0000024, GO:0032480=Reactome:REACT_25271, GO:0005829=Reactome:REACT_25179} Q86VP1 Tax1-binding protein 1 protein 20110201 {GO:0005515=IPI, GO:0043066=IEA, GO:0045087=TAS, GO:0006915=IEA, GO:0032088=ISS, GO:0019900=ISS, GO:0032480=TAS, GO:0005829=TAS} apoptotic process, innate immune response, negative regulation of NF-kappaB transcription factor activity, negative regulation of apoptotic process, negative regulation of type I interferon production cytosol kinase binding, protein binding Human UniProtKB:Q3UKC1 TAX1BP3 BHF-UCL UniProtKB {GO:0005515=PMID:21139582, GO:0005737=PMID:10940294, GO:0008285=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0008013=GO_REF:0000019, GO:0030178=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0007266=PMID:10940294, GO:0008022=PMID:16855024, GO:0016055=GO_REF:0000037, GO:0032864=PMID:21139582, GO:2000009=PMID:16855024} O14907 Tax1-binding protein 3 protein 20101230 {GO:0005515=IPI, GO:0005737=NAS, GO:0008285=IEA, GO:0005886=IEA, GO:0008013=IEA, GO:0030178=ISS, GO:0005634=IEA, GO:0007266=IDA, GO:0008022=IPI, GO:0016055=IEA, GO:0032864=IDA, GO:2000009=IDA} Rho protein signal transduction, Wnt receptor signaling pathway, activation of Cdc42 GTPase activity, negative regulation of Wnt receptor signaling pathway, negative regulation of cell proliferation, negative regulation of protein localization to cell surface cytoplasm, nucleus, plasma membrane beta-catenin binding, protein C-terminus binding, protein binding Human UniProtKB:P03126 TAZ HPA UniProtKB {GO:0030097=PMID:17043667, GO:0047184=PMID:12930833, GO:0016746=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0005743=Reactome:REACT_121265, GO:0035965=Reactome:REACT_121006, GO:0044281=Reactome:REACT_111217, GO:0060048=PMID:17043667, GO:0005739=PMID:15304507, GO:0007507=PMID:17043667, GO:0048738=PMID:17043667, GO:0032981=PMID:16857210, GO:0006936=PMID:17043667, GO:0042775=PMID:15304507, GO:0007519=PMID:17043667, GO:0016021=GO_REF:0000037, GO:0032049=PMID:16873891, GO:0006644=Reactome:REACT_120870, GO:0042407=PMID:17043667, GO:0046474=Reactome:REACT_121401} Q96F92 TAZ protein protein 20110516 {GO:0030097=IMP, GO:0047184=IDA, GO:0016746=IEA, GO:0005886=IDA, GO:0005743=TAS, GO:0035965=TAS, GO:0044281=TAS, GO:0060048=IMP, GO:0005739=IDA, GO:0007507=IMP, GO:0048738=IMP, GO:0032981=IMP, GO:0006936=IMP, GO:0042775=IDA, GO:0007519=IMP, GO:0016021=IEA, GO:0032049=IMP, GO:0006644=TAS, GO:0042407=IMP, GO:0046474=TAS} cardiac muscle contraction, cardiac muscle tissue development, cardiolipin acyl-chain remodeling, cardiolipin biosynthetic process, cristae formation, glycerophospholipid biosynthetic process, heart development, hemopoiesis, mitochondrial ATP synthesis coupled electron transport, mitochondrial respiratory chain complex I assembly, muscle contraction, phospholipid metabolic process, skeletal muscle tissue development, small molecule metabolic process integral to membrane, mitochondrial inner membrane, mitochondrion, plasma membrane 1-acylglycerophosphocholine O-acyltransferase activity, transferase activity, transferring acyl groups Human TBC1D1 Reactome UniProtKB {GO:0032880=GO_REF:0000019, GO:0005622=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0016044=Reactome:REACT_11123, GO:0005097=GO_REF:0000002, GO:0005829=Reactome:REACT_147700} Q86TI0 TBC1 domain family member 1 protein 20110811 {GO:0032880=IEA, GO:0005622=IEA, GO:0005634=IEA, GO:0016044=TAS, GO:0005097=IEA, GO:0005829=TAS} cellular membrane organization, regulation of protein localization cytosol, intracellular, nucleus Rab GTPase activator activity Human TBC1D10A BHF-UCL UniProtKB {GO:0005515=PMID:11285285, GO:0005085=GO_REF:0000037, GO:0005622=GO_REF:0000002, GO:0008150=GO_REF:0000015, GO:0005902=PMID:11285285, GO:0097202=PMID:18387192, GO:0030165=PMID:11285285, GO:0045862=PMID:18387192, GO:0005097=GO_REF:0000002} Q9BXI6 TBC1 domain family member 10A protein 20130219 {GO:0005515=IPI, GO:0005085=IEA, GO:0005622=IEA, GO:0008150=ND, GO:0005902=TAS, GO:0097202=IDA, GO:0030165=IPI, GO:0045862=IDA, GO:0005097=IEA} activation of cysteine-type endopeptidase activity, biological_process, positive regulation of proteolysis intracellular, microvillus PDZ domain binding, Rab GTPase activator activity, guanyl-nucleotide exchange factor activity, protein binding Human TBC1D10B GOC UniProtKB {GO:0005622=GO_REF:0000002, GO:0032313=PMID:19077034, GO:0005737=GO_REF:0000039, GO:0032851=PMID:19077034, GO:0005097=PMID:19077034} Q4KMP7 TBC1 domain family member 10B protein 20130413 {GO:0005622=IEA, GO:0032313=IDA, GO:0005737=IEA, GO:0032851=IDA, GO:0005097=IDA} positive regulation of Rab GTPase activity, regulation of Rab GTPase activity cytoplasm, intracellular Rab GTPase activator activity Human TBC1D10C InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0005097=GO_REF:0000002} Q8IV04 Carabin protein 20130413 {GO:0005622=IEA, GO:0005097=IEA} intracellular Rab GTPase activator activity Human InterPro:IPR000195 TBC1D13 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0005097=GO_REF:0000002} Q9NVG8 TBC1 domain family member 13 protein 20130413 {GO:0005622=IEA, GO:0005097=IEA} intracellular Rab GTPase activator activity Human InterPro:IPR000195 TBC1D14 BHF-UCL UniProtKB {GO:0005622=GO_REF:0000002, GO:0005776=PMID:22613832, GO:0005794=GO_REF:0000039, GO:0019901=PMID:22613832, GO:0010507=PMID:22613832, GO:2000785=PMID:22613832, GO:0005097=GO_REF:0000002} Q9P2M4 TBC1 domain family member 14 protein 20120903 {GO:0005622=IEA, GO:0005776=IDA, GO:0005794=IEA, GO:0019901=IPI, GO:0010507=IMP, GO:2000785=IMP, GO:0005097=IEA} negative regulation of autophagy, regulation of autophagic vacuole assembly Golgi apparatus, autophagic vacuole, intracellular Rab GTPase activator activity, protein kinase binding Human TBC1D15 IntAct UniProtKB {GO:0005515=PMID:20562859, GO:0005622=GO_REF:0000002, GO:0005739=GO_REF:0000019, GO:0032313=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0005576=GO_REF:0000019, GO:0005097=GO_REF:0000024} Q8TC07 TBC1 domain family member 15 protein 20130415 {GO:0005515=IPI, GO:0005622=IEA, GO:0005739=IEA, GO:0032313=ISS, GO:0005737=ISS, GO:0005576=IEA, GO:0005097=ISS} regulation of Rab GTPase activity cytoplasm, extracellular region, intracellular, mitochondrion Rab GTPase activator activity, protein binding Human UniProtKB:Q9H0R8 TBC1D16 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0005097=GO_REF:0000002} Q8TBP0 TBC1 domain family member 16 protein 20130413 {GO:0005622=IEA, GO:0005097=IEA} intracellular Rab GTPase activator activity Human InterPro:IPR000195 TBC1D17 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0005097=GO_REF:0000002} Q9HA65 TBC1 domain family member 17 protein 20130413 {GO:0005622=IEA, GO:0005097=IEA} intracellular Rab GTPase activator activity Human InterPro:IPR000195 TBC1D19 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0005097=GO_REF:0000002} Q8N5T2 TBC1 domain family member 19 protein 20130413 {GO:0005622=IEA, GO:0005097=IEA} intracellular Rab GTPase activator activity Human InterPro:IPR000195 TBC1D2 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0045296=PMID:20116244, GO:0030054=PMID:20116244, GO:0005543=GO_REF:0000002, GO:0032851=PMID:20116244, GO:0016023=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0031410=PMID:20116244, GO:0005097=PMID:20116244} Q9BYX2 TBC1 domain family member 2A protein 20101115 {GO:0005737=IDA, GO:0045296=IPI, GO:0030054=IDA, GO:0005543=IEA, GO:0032851=IDA, GO:0016023=IEA, GO:0005634=IDA, GO:0031410=IDA, GO:0005097=IDA} positive regulation of Rab GTPase activity cell junction, cytoplasm, cytoplasmic membrane-bounded vesicle, cytoplasmic vesicle, nucleus Rab GTPase activator activity, cadherin binding, phospholipid binding Human TBC1D20 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005097=GO_REF:0000002} Q96BZ9 TBC1 domain family member 20 protein 20130413 {GO:0005622=IEA, GO:0019048=IEA, GO:0016021=IEA, GO:0005097=IEA} virus-host interaction integral to membrane, intracellular Rab GTPase activator activity Human UniProtKB-KW:KW-0945 TBC1D21 ENSEMBL UniProtKB {GO:0005622=GO_REF:0000002, GO:0001669=GO_REF:0000019, GO:0003779=GO_REF:0000019, GO:0005097=GO_REF:0000002} Q8IYX1 TBC1 domain family member 21 protein 20130413 {GO:0005622=IEA, GO:0001669=IEA, GO:0003779=IEA, GO:0005097=IEA} acrosomal vesicle, intracellular Rab GTPase activator activity, actin binding Human Ensembl:ENSMUSP00000037525 TBC1D22B InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0005097=GO_REF:0000002} Q9NU19 TBC1 domain family member 22B protein 20130413 {GO:0005622=IEA, GO:0005097=IEA} intracellular Rab GTPase activator activity Human InterPro:IPR000195 TBC1D23 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0005097=GO_REF:0000002} Q9NUY8 TBC1 domain family member 23 protein 20130413 {GO:0005622=IEA, GO:0005097=IEA} intracellular Rab GTPase activator activity Human InterPro:IPR000195 TBC1D24 HPA UniProtKB {GO:0005515=PMID:20727515, GO:0005737=GO_REF:0000052, GO:0031175=PMID:20727515, GO:0005097=GO_REF:0000002} Q9ULP9 TBC1 domain family member 24 protein 20111111 {GO:0005515=IPI, GO:0005737=IDA, GO:0031175=IMP, GO:0005097=IEA} neuron projection development cytoplasm Rab GTPase activator activity, protein binding Human TBC1D25 GOC UniProtKB {GO:0005515=PMID:21383079, GO:0005776=PMID:21383079, GO:0006914=GO_REF:0000037, GO:0032851=PMID:21383079, GO:1901096=PMID:21383079, GO:0031410=GO_REF:0000037, GO:0005097=PMID:21383079} Q3MII6 TBC1 domain family member 25 protein 20130413 {GO:0005515=IPI, GO:0005776=IDA, GO:0006914=IEA, GO:0032851=IDA, GO:1901096=IMP, GO:0031410=IEA, GO:0005097=IDA} autophagy, positive regulation of Rab GTPase activity, regulation of autophagic vacuole maturation autophagic vacuole, cytoplasmic vesicle Rab GTPase activator activity, protein binding Human TBC1D2B IntAct UniProtKB {GO:0005515=PMID:20562859, GO:0005622=GO_REF:0000002, GO:0005543=GO_REF:0000002, GO:0005097=GO_REF:0000002} Q9UPU7 TBC1 domain family member 2B protein 20130415 {GO:0005515=IPI, GO:0005622=IEA, GO:0005543=IEA, GO:0005097=IEA} intracellular Rab GTPase activator activity, phospholipid binding, protein binding Human UniProtKB:Q9H0R8 TBC1D3 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0004177=GO_REF:0000002, GO:0006508=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0008237=GO_REF:0000002, GO:0005097=GO_REF:0000002} Q8IZP1 TBC1 domain family member 3 protein 20130413 {GO:0005622=IEA, GO:0004177=IEA, GO:0006508=IEA, GO:0008270=IEA, GO:0008237=IEA, GO:0005097=IEA} proteolysis intracellular Rab GTPase activator activity, aminopeptidase activity, metallopeptidase activity, zinc ion binding Human InterPro:IPR000195 TBC1D3C InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0005097=GO_REF:0000002} Q6IPX1 TBC1 domain family member 3C protein 20130413 {GO:0005622=IEA, GO:0005097=IEA} intracellular Rab GTPase activator activity Human InterPro:IPR000195 TBC1D3F InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0005097=GO_REF:0000002} F5GZ95 TBC1 domain family member 3F protein 20130413 {GO:0005622=IEA, GO:0005097=IEA} intracellular Rab GTPase activator activity Human InterPro:IPR000195 TBC1D4 Reactome UniProtKB {GO:0032869=PMID:22908308, GO:0016192=PMID:22908308, GO:0030659=Reactome:REACT_147698, GO:0016044=Reactome:REACT_11123, GO:0005097=GO_REF:0000002} O60343 TBC1 domain family member 4 protein 20120519 {GO:0032869=IMP, GO:0016192=IMP, GO:0030659=TAS, GO:0016044=TAS, GO:0005097=IEA} cellular membrane organization, cellular response to insulin stimulus, vesicle-mediated transport cytoplasmic vesicle membrane Rab GTPase activator activity Human TBC1D5 IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0005622=GO_REF:0000002, GO:0005097=GO_REF:0000002, GO:0030904=PMID:20923837} Q92609 TBC1 domain family member 5 protein 20130415 {GO:0005515=IPI, GO:0005622=IEA, GO:0005097=IEA, GO:0030904=IDA} intracellular, retromer complex Rab GTPase activator activity, protein binding Human UniProtKB:P54253 TBC1D7 UniProtKB UniProtKB {GO:0005515=PMID:17658474, GO:0005622=GO_REF:0000002, GO:0032007=PMID:22795129, GO:0031398=PMID:17658474, GO:0016023=GO_REF:0000039, GO:0031410=PMID:17658474, GO:0032862=PMID:22795129, GO:0070848=PMID:22795129, GO:0005097=GO_REF:0000002} Q9P0N9 TBC1 domain family member 7 protein 20120727 {GO:0005515=IPI, GO:0005622=IEA, GO:0032007=IMP, GO:0031398=IDA, GO:0016023=IEA, GO:0031410=IDA, GO:0032862=IMP, GO:0070848=IMP, GO:0005097=IEA} activation of Rho GTPase activity, negative regulation of TOR signaling cascade, positive regulation of protein ubiquitination, response to growth factor stimulus cytoplasmic membrane-bounded vesicle, cytoplasmic vesicle, intracellular Rab GTPase activator activity, protein binding Human TBC1D8 PINC UniProtKB {GO:0005622=GO_REF:0000002, GO:0008284=PMID:10373574, GO:0016020=PMID:10373574, GO:0008015=PMID:10373574, GO:0005509=GO_REF:0000002, GO:0005097=GO_REF:0000002} O95759 TBC1 domain family member 8 protein 20030904 {GO:0005622=IEA, GO:0008284=TAS, GO:0016020=TAS, GO:0008015=TAS, GO:0005509=IEA, GO:0005097=IEA} blood circulation, positive regulation of cell proliferation intracellular, membrane Rab GTPase activator activity, calcium ion binding Human TBC1D8B InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0005097=GO_REF:0000002} Q0IIM8 TBC1 domain family member 8B protein 20130413 {GO:0005622=IEA, GO:0005509=IEA, GO:0005097=IEA} intracellular Rab GTPase activator activity, calcium ion binding Human InterPro:IPR000195 TBC1D9 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0005097=GO_REF:0000002} Q6ZT07 TBC1 domain family member 9 protein 20130413 {GO:0005622=IEA, GO:0005509=IEA, GO:0005097=IEA} intracellular Rab GTPase activator activity, calcium ion binding Human InterPro:IPR000195 TBC1D9B UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0005509=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005097=GO_REF:0000002} Q66K14 TBC1 domain family member 9B protein 20130413 {GO:0005622=IEA, GO:0005509=IEA, GO:0016021=IEA, GO:0005097=IEA} integral to membrane, intracellular Rab GTPase activator activity, calcium ion binding Human UniProtKB-KW:KW-0812 TBCA HPA UniProtKB {GO:0005737=PMID:16130169, GO:0006457=PMID:8706133, GO:0007021=GO_REF:0000002, GO:0015630=GO_REF:0000052, GO:0005874=GO_REF:0000037, GO:0051087=PMID:8706133, GO:0005730=GO_REF:0000052, GO:0051084=Reactome:REACT_16952, GO:0007023=PMID:8706133, GO:0051082=GO_REF:0000002, GO:0044267=Reactome:REACT_17015} O75347 Tubulin-specific chaperone A protein 20111111 {GO:0005737=TAS, GO:0006457=TAS, GO:0007021=IEA, GO:0015630=IDA, GO:0005874=IEA, GO:0051087=TAS, GO:0005730=IDA, GO:0051084=TAS, GO:0007023=TAS, GO:0051082=IEA, GO:0044267=TAS} 'de novo' posttranslational protein folding, cellular protein metabolic process, post-chaperonin tubulin folding pathway, protein folding, tubulin complex assembly cytoplasm, microtubule, microtubule cytoskeleton, nucleolus chaperone binding, unfolded protein binding Human TBCB HPA UniProtKB {GO:0005515=PMID:16713569, GO:0005737=GO_REF:0000052, GO:0015630=PMID:8978778, GO:0005874=GO_REF:0000037, GO:0051084=Reactome:REACT_16952, GO:0044267=Reactome:REACT_17015, GO:0030154=GO_REF:0000037, GO:0007399=GO_REF:0000037} Q99426 Tubulin-folding cofactor B protein 20111111 {GO:0005515=IPI, GO:0005737=IDA, GO:0015630=TAS, GO:0005874=IEA, GO:0051084=TAS, GO:0044267=TAS, GO:0030154=IEA, GO:0007399=IEA} 'de novo' posttranslational protein folding, cell differentiation, cellular protein metabolic process, nervous system development cytoplasm, microtubule, microtubule cytoskeleton protein binding Human TBCC GOC UniProtKB {GO:0006184=PMID:11847227, GO:0000902=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0006457=PMID:8706133, GO:0005874=PMID:8706133, GO:0051087=PMID:8706133, GO:0003924=PMID:11847227, GO:0051084=Reactome:REACT_16952, GO:0032391=PMID:12417528, GO:0007023=PMID:11847227, GO:0005856=PMID:8706133, GO:0044267=Reactome:REACT_17015} Q15814 Tubulin-specific chaperone C protein 20130413 {GO:0006184=IDA, GO:0000902=IEA, GO:0005737=IDA, GO:0006457=TAS, GO:0005874=TAS, GO:0051087=TAS, GO:0003924=IDA, GO:0051084=TAS, GO:0032391=IDA, GO:0007023=IDA, GO:0005856=TAS, GO:0044267=TAS} 'de novo' posttranslational protein folding, GTP catabolic process, cell morphogenesis, cellular protein metabolic process, post-chaperonin tubulin folding pathway, protein folding cytoplasm, cytoskeleton, microtubule, photoreceptor connecting cilium GTPase activity, chaperone binding Human TBCCD1 UniProtKB UniProtKB {GO:0030334=PMID:20168327, GO:0000902=GO_REF:0000002, GO:0005737=GO_REF:0000037, GO:0051661=PMID:20168327, GO:0008360=PMID:20168327, GO:0031616=PMID:20168327, GO:0051684=PMID:20168327} Q9NVR7 TBCC domain-containing protein 1 protein 20110221 {GO:0030334=IMP, GO:0000902=IEA, GO:0005737=IEA, GO:0051661=IMP, GO:0008360=IMP, GO:0031616=IDA, GO:0051684=IMP} cell morphogenesis, maintenance of Golgi location, maintenance of centrosome location, regulation of cell migration, regulation of cell shape cytoplasm, spindle pole centrosome Human TBCD GOC UniProtKB {GO:0005515=PMID:10831612, GO:0031115=PMID:20740604, GO:0005874=PMID:8706133, GO:0034333=GO_REF:0000024, GO:0051087=PMID:8706133, GO:0048487=PMID:10831612, GO:0010812=GO_REF:0000024, GO:0016328=GO_REF:0000024, GO:0043547=PMID:20740604, GO:0005737=GO_REF:0000039, GO:0070830=GO_REF:0000024, GO:0005912=GO_REF:0000024, GO:0006457=PMID:20740604, GO:0051084=Reactome:REACT_16952, GO:0007023=PMID:11847227, GO:0005923=GO_REF:0000024, GO:0044267=Reactome:REACT_17015, GO:0005096=PMID:20740604} Q9BTW9 Tubulin-specific chaperone D protein 20130413 {GO:0005515=IPI, GO:0031115=IDA, GO:0005874=TAS, GO:0034333=ISS, GO:0051087=TAS, GO:0048487=IDA, GO:0010812=ISS, GO:0016328=ISS, GO:0043547=IDA, GO:0005737=IEA, GO:0070830=ISS, GO:0005912=ISS, GO:0006457=IDA, GO:0051084=TAS, GO:0007023=IDA, GO:0005923=ISS, GO:0044267=TAS, GO:0005096=IDA} 'de novo' posttranslational protein folding, adherens junction assembly, cellular protein metabolic process, negative regulation of cell-substrate adhesion, negative regulation of microtubule polymerization, positive regulation of GTPase activity, post-chaperonin tubulin folding pathway, protein folding, tight junction assembly adherens junction, cytoplasm, lateral plasma membrane, microtubule, tight junction GTPase activator activity, beta-tubulin binding, chaperone binding, protein binding Human TBCE Reactome UniProtKB {GO:0008344=GO_REF:0000019, GO:0003735=GO_REF:0000002, GO:0005874=PMID:8706133, GO:0051087=PMID:8706133, GO:0000226=GO_REF:0000019, GO:0009791=GO_REF:0000019, GO:0006412=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0048589=GO_REF:0000019, GO:0006457=PMID:8706133, GO:0014889=GO_REF:0000019, GO:0051084=Reactome:REACT_16952, GO:0005840=GO_REF:0000002, GO:0048936=GO_REF:0000019, GO:0007023=PMID:11847227, GO:0044267=Reactome:REACT_17015} Q15813 Tubulin-specific chaperone E protein 20130213 {GO:0008344=IEA, GO:0003735=IEA, GO:0005874=TAS, GO:0051087=TAS, GO:0000226=IEA, GO:0009791=IEA, GO:0006412=IEA, GO:0005737=IEA, GO:0048589=IEA, GO:0006457=TAS, GO:0014889=IEA, GO:0051084=TAS, GO:0005840=IEA, GO:0048936=IEA, GO:0007023=IDA, GO:0044267=TAS} 'de novo' posttranslational protein folding, adult locomotory behavior, cellular protein metabolic process, developmental growth, microtubule cytoskeleton organization, muscle atrophy, peripheral nervous system neuron axonogenesis, post-chaperonin tubulin folding pathway, post-embryonic development, protein folding, translation cytoplasm, microtubule, ribosome chaperone binding, structural constituent of ribosome Human TBCEL UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0005856=GO_REF:0000039} Q5QJ74 Tubulin-specific chaperone cofactor E-like protein protein 20130413 {GO:0005737=IEA, GO:0005856=IEA} cytoplasm, cytoskeleton Human UniProtKB-SubCell:SL-0090 TBCK UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0004672=PMID:12471243, GO:0006468=PMID:12471243, GO:0005524=PMID:12471243, GO:0005097=GO_REF:0000002} Q8TEA7 TBC domain-containing protein kinase-like protein protein 20061211 {GO:0005622=IEA, GO:0004672=RCA, GO:0006468=RCA, GO:0005524=RCA, GO:0005097=IEA} protein phosphorylation intracellular ATP binding, Rab GTPase activator activity, protein kinase activity Human TBK1 BHF-UCL UniProtKB {GO:0051219=PMID:14530355, GO:0005515=PMID:22000020, GO:0034142=Reactome:REACT_6894, GO:0050830=GO_REF:0000019, GO:0007249=PMID:21042276, GO:0002218=GO_REF:0000019, GO:0005829=Reactome:REACT_147901, GO:0002756=Reactome:REACT_6809, GO:0005737=PMID:21813773, GO:0051607=GO_REF:0000037, GO:0006954=PMID:21042276, GO:0045944=PMID:16127453, GO:0032606=PMID:21042276, GO:0032481=Reactome:REACT_147841, GO:0043123=PMID:12761501, GO:0034138=Reactome:REACT_6783, GO:0032480=Reactome:REACT_25271, GO:0032728=PMID:16127453, GO:0032727=PMID:16127453, GO:0003676=GO_REF:0000019, GO:0009615=PMID:21042276, GO:0002224=Reactome:REACT_6966, GO:0005524=GO_REF:0000037, GO:0045359=GO_REF:0000019, GO:0004672=Reactome:REACT_25368, GO:0004674=Reactome:REACT_147769, GO:0019048=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0010629=GO_REF:0000019, GO:0035666=Reactome:REACT_25281, GO:0010008=Reactome:REACT_25081} Q9UHD2 Serine/threonine-protein kinase TBK1 protein 20110310 {GO:0051219=IPI, GO:0005515=IPI, GO:0034142=TAS, GO:0050830=IEA, GO:0007249=TAS, GO:0002218=IEA, GO:0005829=TAS, GO:0002756=TAS, GO:0005737=IDA, GO:0051607=IEA, GO:0006954=TAS, GO:0045944=IDA, GO:0032606=TAS, GO:0032481=TAS, GO:0043123=IEP, GO:0034138=TAS, GO:0032480=TAS, GO:0032728=IDA, GO:0032727=IDA, GO:0003676=IEA, GO:0009615=TAS, GO:0002224=TAS, GO:0005524=IEA, GO:0045359=IEA, GO:0004672=TAS, GO:0004674=TAS, GO:0019048=IEA, GO:0045087=TAS, GO:0010629=IEA, GO:0035666=TAS, GO:0010008=TAS} I-kappaB kinase/NF-kappaB cascade, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, activation of innate immune response, defense response to Gram-positive bacterium, defense response to virus, inflammatory response, innate immune response, negative regulation of gene expression, negative regulation of type I interferon production, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of interferon-alpha production, positive regulation of interferon-beta biosynthetic process, positive regulation of interferon-beta production, positive regulation of transcription from RNA polymerase II promoter, positive regulation of type I interferon production, response to virus, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor signaling pathway, type I interferon production, virus-host interaction cytoplasm, cytosol, endosome membrane ATP binding, nucleic acid binding, phosphoprotein binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human TBKBP1 IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0045087=GO_REF:0000037} A7MCY6 TANK-binding kinase 1-binding protein 1 protein 20130415 {GO:0005515=IPI, GO:0045087=IEA} innate immune response protein binding Human UniProtKB:Q9UKV8 TBL1X Reactome UniProtKB {GO:0005515=PMID:12628926, GO:0044212=PMID:18193033, GO:0008013=PMID:18193033, GO:0007605=PMID:10330347, GO:0003714=PMID:12628926, GO:0019904=PMID:10809664, GO:0005634=PMID:18193033, GO:0044281=Reactome:REACT_111217, GO:0000122=PMID:12628926, GO:0008022=PMID:18374649, GO:0006351=GO_REF:0000037, GO:0042393=PMID:15601853, GO:0000118=PMID:18326024, GO:0007219=Reactome:REACT_118859, GO:0045944=PMID:18193033, GO:0017053=PMID:12628926, GO:0006508=PMID:18374649, GO:0005654=Reactome:REACT_160192, GO:0005876=PMID:18326024, GO:0043161=GO_REF:0000024, GO:0045893=PMID:18193033, GO:0060070=PMID:18193033, GO:0044255=Reactome:REACT_22279, GO:0008134=PMID:18193033} O60907 F-box-like/WD repeat-containing protein TBL1X protein 20080614 {GO:0005515=IPI, GO:0044212=IDA, GO:0008013=IPI, GO:0007605=IMP, GO:0003714=IDA, GO:0019904=IPI, GO:0005634=IDA, GO:0044281=TAS, GO:0000122=IDA, GO:0008022=IPI, GO:0006351=IEA, GO:0042393=IDA, GO:0000118=IDA, GO:0007219=TAS, GO:0045944=IDA, GO:0017053=IDA, GO:0006508=IMP, GO:0005654=TAS, GO:0005876=IDA, GO:0043161=ISS, GO:0045893=IDA, GO:0060070=IMP, GO:0044255=TAS, GO:0008134=IPI} Notch signaling pathway, canonical Wnt receptor signaling pathway, cellular lipid metabolic process, negative regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, proteasomal ubiquitin-dependent protein catabolic process, proteolysis, sensory perception of sound, small molecule metabolic process, transcription, DNA-dependent histone deacetylase complex, nucleoplasm, nucleus, spindle microtubule, transcriptional repressor complex beta-catenin binding, histone binding, protein C-terminus binding, protein binding, protein domain specific binding, transcription corepressor activity, transcription factor binding, transcription regulatory region DNA binding Human TBL1XR1 HPA UniProtKB {GO:0005515=PMID:12628926, GO:0008013=PMID:18193033, GO:0044212=GO_REF:0000024, GO:0003714=PMID:12628926, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0000122=PMID:12628926, GO:0006351=GO_REF:0000037, GO:0042393=PMID:15601853, GO:0047485=PMID:16893456, GO:0000118=PMID:18326024, GO:0007219=Reactome:REACT_118859, GO:0045944=PMID:18193033, GO:0017053=PMID:12628926, GO:0005654=Reactome:REACT_160192, GO:0005876=PMID:18326024, GO:0043161=GO_REF:0000024, GO:0045893=PMID:18193033, GO:0045892=GO_REF:0000019, GO:0060070=PMID:18193033, GO:0044255=Reactome:REACT_22279, GO:0016568=GO_REF:0000037} Q9BZK7 F-box-like/WD repeat-containing protein TBL1XR1 protein 20100326 {GO:0005515=IPI, GO:0008013=IPI, GO:0044212=ISS, GO:0003714=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0000122=IDA, GO:0006351=IEA, GO:0042393=IDA, GO:0047485=IPI, GO:0000118=IDA, GO:0007219=TAS, GO:0045944=IDA, GO:0017053=IDA, GO:0005654=TAS, GO:0005876=IDA, GO:0043161=ISS, GO:0045893=IDA, GO:0045892=IEA, GO:0060070=IMP, GO:0044255=TAS, GO:0016568=IEA} Notch signaling pathway, canonical Wnt receptor signaling pathway, cellular lipid metabolic process, chromatin modification, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, proteasomal ubiquitin-dependent protein catabolic process, small molecule metabolic process, transcription, DNA-dependent histone deacetylase complex, nucleolus, nucleoplasm, nucleus, spindle microtubule, transcriptional repressor complex beta-catenin binding, histone binding, protein N-terminus binding, protein binding, transcription corepressor activity, transcription regulatory region DNA binding NOT Human TBL2 BHF-UCL UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q9Y4P3 Transducin beta-like protein 2 protein 20080307 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human TBL3 HPA UniProtKB {GO:0006364=GO_REF:0000002, GO:0007199=PMID:8307582, GO:0032040=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005057=PMID:8307582} Q12788 Transducin beta-like protein 3 protein 20111111 {GO:0006364=IEA, GO:0007199=TAS, GO:0032040=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005057=TAS} G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger, rRNA processing nucleolus, nucleus, small-subunit processome receptor signaling protein activity Human TBP ENSEMBL UniProtKB {GO:0005515=PMID:11029584, GO:0008219=GO_REF:0000037, GO:0010467=Reactome:REACT_71, GO:0022415=Reactome:REACT_6361, GO:0006368=Reactome:REACT_2089, GO:0006367=Reactome:REACT_1851, GO:0044212=PMID:9027316, GO:0006366=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0006383=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0070491=PMID:18838386, GO:0016032=Reactome:REACT_6256, GO:0001940=GO_REF:0000019, GO:0001103=GO_REF:0000019, GO:0006352=GO_REF:0000002, GO:0005669=GO_REF:0000019, GO:0005719=PMID:19861239, GO:0003677=GO_REF:0000019, GO:0001939=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0005654=Reactome:REACT_1844, GO:0005672=PMID:7724559, GO:0045893=GO_REF:0000019, GO:0008134=PMID:8626665} Q7Z6S5 TATA-box-binding protein protein 20130413 {GO:0005515=IPI, GO:0008219=IEA, GO:0010467=TAS, GO:0022415=TAS, GO:0006368=TAS, GO:0006367=TAS, GO:0044212=IDA, GO:0006366=IEA, GO:0007283=IEA, GO:0006383=IEA, GO:0005737=IEA, GO:0070491=IPI, GO:0016032=TAS, GO:0001940=IEA, GO:0001103=IEA, GO:0006352=IEA, GO:0005669=IEA, GO:0005719=IDA, GO:0003677=IEA, GO:0001939=IEA, GO:0019048=IEA, GO:0005654=TAS, GO:0005672=IDA, GO:0045893=IEA, GO:0008134=IPI} DNA-dependent transcription, initiation, cell death, gene expression, positive regulation of transcription, DNA-dependent, spermatogenesis, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription from RNA polymerase III promoter, transcription initiation from RNA polymerase II promoter, viral reproduction, viral reproductive process, virus-host interaction cytoplasm, female pronucleus, male pronucleus, nuclear euchromatin, nucleoplasm, transcription factor TFIIA complex, transcription factor TFIID complex DNA binding, RNA polymerase II repressing transcription factor binding, protein binding, repressing transcription factor binding, transcription factor binding, transcription regulatory region DNA binding Human Ensembl:ENSRNOP00000002038 TBPL1 InterPro UniProtKB {GO:0001675=GO_REF:0000019, GO:0006352=GO_REF:0000002, GO:0005737=GO_REF:0000019, GO:0006366=PMID:10220372, GO:0007289=GO_REF:0000019, GO:0003713=PMID:10220372, GO:0005672=GO_REF:0000019, GO:0006235=GO_REF:0000019, GO:0003677=GO_REF:0000002} Q7Z6U2 TATA box-binding protein-like protein 1 protein 20130413 {GO:0001675=IEA, GO:0006352=IEA, GO:0005737=IEA, GO:0006366=TAS, GO:0007289=IEA, GO:0003713=TAS, GO:0005672=IEA, GO:0006235=IEA, GO:0003677=IEA} DNA-dependent transcription, initiation, acrosome assembly, dTTP biosynthetic process, spermatid nucleus differentiation, transcription from RNA polymerase II promoter cytoplasm, transcription factor TFIIA complex DNA binding, transcription coactivator activity Human InterPro:IPR000814 TBPL2 UniProtKB UniProtKB {GO:0006352=GO_REF:0000002, GO:0005737=PMID:14634207, GO:0003700=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0005634=PMID:14634207, GO:0045892=GO_REF:0000019, GO:0003677=GO_REF:0000019} Q6SJ96 TATA box-binding protein-like protein 2 protein 20080804 {GO:0006352=IEA, GO:0005737=IDA, GO:0003700=IEA, GO:0007275=IEA, GO:0005634=IDA, GO:0045892=IEA, GO:0003677=IEA} DNA-dependent transcription, initiation, multicellular organismal development, negative regulation of transcription, DNA-dependent cytoplasm, nucleus DNA binding, sequence-specific DNA binding transcription factor activity Human TBR1 PINC UniProtKB {GO:0003700=GO_REF:0000019, GO:0007420=PMID:7619531, GO:0007411=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0010975=GO_REF:0000019, GO:0010092=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000038, GO:0030902=GO_REF:0000019, GO:0000979=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q16650 T-box brain protein 1 protein 20030904 {GO:0003700=IEA, GO:0007420=TAS, GO:0007411=IEA, GO:0045944=IEA, GO:0010975=IEA, GO:0010092=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0030902=IEA, GO:0000979=IEA, GO:0006351=IEA} axon guidance, brain development, hindbrain development, positive regulation of transcription from RNA polymerase II promoter, regulation of neuron projection development, specification of organ identity, transcription, DNA-dependent nucleus DNA binding, RNA polymerase II core promoter sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human TBRG1 HGNC UniProtKB {GO:0006260=PMID:17110379, GO:0005515=PMID:17110379, GO:0008285=PMID:17110379, GO:0050821=PMID:17110379, GO:0007050=PMID:17110379, GO:0005634=PMID:17110379, GO:0032066=PMID:17110379} Q3YBR2 Transforming growth factor beta regulator 1 protein 20071017 {GO:0006260=IMP, GO:0005515=IPI, GO:0008285=IMP, GO:0050821=IMP, GO:0007050=IMP, GO:0005634=IDA, GO:0032066=IDA} DNA replication, cell cycle arrest, negative regulation of cell proliferation, nucleolus to nucleoplasm transport, protein stabilization nucleus protein binding Human TBRG4 UniProtKB UniProtKB {GO:0005739=PMID:20869947, GO:0045333=PMID:20869947, GO:0008284=PMID:9383053, GO:0004672=GO_REF:0000002, GO:0007050=PMID:9383053, GO:0000080=PMID:9383053} Q969Z0 Protein TBRG4 protein 20101208 {GO:0005739=IDA, GO:0045333=ISS, GO:0008284=TAS, GO:0004672=IEA, GO:0007050=TAS, GO:0000080=TAS} G1 phase of mitotic cell cycle, cell cycle arrest, cellular respiration, positive regulation of cell proliferation mitochondrion protein kinase activity Human UniProtKB:Q14CZ7 TBX1 UniProtKB UniProtKB {GO:0007389=GO_REF:0000024, GO:0003700=PMID:11111039, GO:0071300=GO_REF:0000024, GO:0007605=GO_REF:0000024, GO:0001755=GO_REF:0000024, GO:0048538=PMID:14585638, GO:0048844=GO_REF:0000024, GO:0030878=GO_REF:0000024, GO:0048703=PMID:14585638, GO:0048752=GO_REF:0000024, GO:0048701=GO_REF:0000024, GO:0042803=PMID:11111039, GO:0042693=GO_REF:0000024, GO:0007507=PMID:14585638, GO:0048644=GO_REF:0000024, GO:0001945=GO_REF:0000024, GO:0050679=GO_REF:0000024, GO:0042471=GO_REF:0000024, GO:0042472=GO_REF:0000024, GO:0001708=GO_REF:0000024, GO:0021644=GO_REF:0000024, GO:0060037=PMID:14585638, GO:0048384=GO_REF:0000024, GO:0007517=GO_REF:0000024, GO:0035176=GO_REF:0000024, GO:0045596=GO_REF:0000024, GO:0045893=GO_REF:0000024, GO:0043587=GO_REF:0000024, GO:2001054=GO_REF:0000024, GO:0007368=GO_REF:0000024, GO:0008284=GO_REF:0000024, GO:0008283=GO_REF:0000024, GO:2000027=GO_REF:0000024, GO:0048514=GO_REF:0000024, GO:0005634=PMID:15703190, GO:0009952=GO_REF:0000024, GO:0045944=GO_REF:0000024, GO:0030855=GO_REF:0000024, GO:0090103=GO_REF:0000024, GO:0072513=GO_REF:0000019, GO:0042475=GO_REF:0000024, GO:0042474=GO_REF:0000024, GO:0042473=GO_REF:0000024, GO:2001037=GO_REF:0000024, GO:0060023=PMID:14585638, GO:0097152=GO_REF:0000024, GO:0060415=GO_REF:0000024, GO:0001568=GO_REF:0000024, GO:0006357=GO_REF:0000024, GO:0070166=GO_REF:0000024, GO:0035909=GO_REF:0000024, GO:0002053=GO_REF:0000024, GO:0001525=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0003151=GO_REF:0000024, GO:0044344=GO_REF:0000024, GO:0071600=GO_REF:0000019, GO:0043565=PMID:11111039, GO:0003007=GO_REF:0000024, GO:0060017=PMID:14585638, GO:0060325=GO_REF:0000024, GO:0001974=GO_REF:0000019, GO:0003148=GO_REF:0000024, GO:0060982=GO_REF:0000024, GO:0001934=GO_REF:0000024, GO:0007498=GO_REF:0000024, GO:0043410=GO_REF:0000024} O43435 T-box transcription factor TBX1 protein 20110906 {GO:0007389=ISS, GO:0003700=IDA, GO:0071300=ISS, GO:0007605=ISS, GO:0001755=ISS, GO:0048538=IMP, GO:0048844=ISS, GO:0030878=ISS, GO:0048703=IMP, GO:0048752=ISS, GO:0048701=ISS, GO:0042803=IDA, GO:0042693=ISS, GO:0007507=IMP, GO:0048644=ISS, GO:0001945=ISS, GO:0050679=ISS, GO:0042471=ISS, GO:0042472=ISS, GO:0001708=ISS, GO:0021644=ISS, GO:0060037=IMP, GO:0048384=ISS, GO:0007517=ISS, GO:0035176=ISS, GO:0045596=ISS, GO:0045893=ISS, GO:0043587=ISS, GO:2001054=ISS, GO:0007368=ISS, GO:0008284=ISS, GO:0008283=ISS, GO:2000027=ISS, GO:0048514=ISS, GO:0005634=IDA, GO:0009952=ISS, GO:0045944=ISS, GO:0030855=ISS, GO:0090103=ISS, GO:0072513=IEA, GO:0042475=ISS, GO:0042474=ISS, GO:0042473=ISS, GO:2001037=ISS, GO:0060023=IMP, GO:0097152=ISS, GO:0060415=ISS, GO:0001568=ISS, GO:0006357=ISS, GO:0070166=ISS, GO:0035909=ISS, GO:0002053=ISS, GO:0001525=ISS, GO:0006351=IEA, GO:0003151=ISS, GO:0044344=ISS, GO:0071600=IEA, GO:0043565=IDA, GO:0003007=ISS, GO:0060017=IMP, GO:0060325=ISS, GO:0001974=IEA, GO:0003148=ISS, GO:0060982=ISS, GO:0001934=ISS, GO:0007498=ISS, GO:0043410=ISS} angiogenesis, anterior/posterior pattern specification, aorta morphogenesis, artery morphogenesis, blood vessel development, blood vessel morphogenesis, blood vessel remodeling, cell fate specification, cell proliferation, cellular response to fibroblast growth factor stimulus, cellular response to retinoic acid, cochlea morphogenesis, coronary artery morphogenesis, determination of left/right symmetry, ear morphogenesis, embryonic cranial skeleton morphogenesis, embryonic viscerocranium morphogenesis, enamel mineralization, epithelial cell differentiation, face morphogenesis, heart development, heart morphogenesis, inner ear morphogenesis, lymph vessel development, mesenchymal cell apoptotic process, mesoderm development, middle ear morphogenesis, muscle cell fate commitment, muscle organ development, muscle organ morphogenesis, muscle tissue morphogenesis, negative regulation of cell differentiation, negative regulation of mesenchymal cell apoptotic process, neural crest cell migration, odontogenesis of dentin-containing tooth, otic vesicle morphogenesis, outer ear morphogenesis, outflow tract morphogenesis, outflow tract septum morphogenesis, parathyroid gland development, pattern specification process, pharyngeal system development, positive regulation of MAPK cascade, positive regulation of cell proliferation, positive regulation of epithelial cell proliferation, positive regulation of mesenchymal cell proliferation, positive regulation of protein phosphorylation, positive regulation of secondary heart field cardioblast proliferation, positive regulation of tongue muscle cell differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of organ morphogenesis, regulation of transcription from RNA polymerase II promoter, retinoic acid receptor signaling pathway, semicircular canal morphogenesis, sensory perception of sound, social behavior, soft palate development, thymus development, thyroid gland development, tongue morphogenesis, transcription, DNA-dependent, vagus nerve morphogenesis nucleus protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:P70323 TBX19 PINC UniProtKB {GO:0045165=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0006357=PMID:9888994, GO:0045944=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0021983=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0009653=PMID:9888994, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037} O60806 T-box transcription factor TBX19 protein 20031119 {GO:0045165=IEA, GO:0003700=IEA, GO:0006357=TAS, GO:0045944=IEA, GO:0042127=IEA, GO:0021983=IEA, GO:0005634=IEA, GO:0009653=TAS, GO:0003677=IEA, GO:0006351=IEA} anatomical structure morphogenesis, cell fate commitment, pituitary gland development, positive regulation of transcription from RNA polymerase II promoter, regulation of cell proliferation, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity Human TBX2 BHF-UCL UniProtKB {GO:0005515=PMID:22002537, GO:0060045=GO_REF:0000024, GO:0008284=PMID:11748239, GO:0060596=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0005634=GO_REF:0000002, GO:0048596=GO_REF:0000024, GO:1901208=GO_REF:0000024, GO:0060021=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:1901211=GO_REF:0000024, GO:0007569=PMID:11748239, GO:0035909=GO_REF:0000024, GO:0003203=GO_REF:0000024, GO:0000122=GO_REF:0000019, GO:0007521=GO_REF:0000024, GO:0060560=GO_REF:0000019, GO:0003677=PMID:8530034, GO:0006351=GO_REF:0000037, GO:0003151=GO_REF:0000024, GO:0036302=GO_REF:0000024, GO:0043565=PMID:11111039, GO:0048738=GO_REF:0000024, GO:0060465=GO_REF:0000024, GO:0003148=GO_REF:0000024, GO:0045892=PMID:11111039, GO:0042733=GO_REF:0000024, GO:0090398=PMID:22002537, GO:0003256=GO_REF:0000024} Q13207 T-box transcription factor TBX2 protein 20120727 {GO:0005515=IPI, GO:0060045=ISS, GO:0008284=IDA, GO:0060596=IEA, GO:0003700=IEA, GO:0005634=IEA, GO:0048596=ISS, GO:1901208=ISS, GO:0060021=IEA, GO:0005667=IEA, GO:1901211=ISS, GO:0007569=IDA, GO:0035909=ISS, GO:0003203=ISS, GO:0000122=IEA, GO:0007521=ISS, GO:0060560=IEA, GO:0003677=TAS, GO:0006351=IEA, GO:0003151=ISS, GO:0036302=ISS, GO:0043565=IDA, GO:0048738=ISS, GO:0060465=ISS, GO:0003148=ISS, GO:0045892=IDA, GO:0042733=ISS, GO:0090398=IDA, GO:0003256=ISS} aorta morphogenesis, atrioventricular canal development, cardiac muscle tissue development, cell aging, cellular senescence, developmental growth involved in morphogenesis, embryonic camera-type eye morphogenesis, embryonic digit morphogenesis, endocardial cushion morphogenesis, mammary placode formation, muscle cell fate determination, negative regulation of cardiac chamber formation, negative regulation of heart looping, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, outflow tract morphogenesis, outflow tract septum morphogenesis, palate development, pharynx development, positive regulation of cardiac muscle cell proliferation, positive regulation of cell proliferation, regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation, transcription, DNA-dependent nucleus, transcription factor complex DNA binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:Q60707 TBX20 GOC UniProtKB {GO:0060045=GO_REF:0000024, GO:0035922=PMID:19762328, GO:0060577=PMID:18834961, GO:0010991=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0003180=PMID:18834961, GO:0008283=GO_REF:0000019, GO:0008015=GO_REF:0000019, GO:0003215=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0009953=GO_REF:0000024, GO:0003143=GO_REF:0000024, GO:0001947=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0006936=GO_REF:0000019, GO:0045944=PMID:19762328, GO:0001085=GO_REF:0000024, GO:0048370=GO_REF:0000024, GO:0055008=GO_REF:0000024, GO:0001102=GO_REF:0000024, GO:0021524=GO_REF:0000024, GO:0003279=GO_REF:0000024, GO:0001569=GO_REF:0000019, GO:0001706=GO_REF:0000024, GO:0001105=PMID:19762328, GO:0000977=PMID:19762328, GO:0060413=PMID:19762328, GO:0003272=GO_REF:0000024, GO:0003175=GO_REF:0000024, GO:0003203=GO_REF:0000024, GO:0003193=GO_REF:0000024, GO:0036306=GO_REF:0000019, GO:0000122=GO_REF:0000024, GO:0003207=GO_REF:0000024, GO:0003344=GO_REF:0000024, GO:0003148=PMID:18834961, GO:0001764=GO_REF:0000019, GO:0045892=GO_REF:0000024} Q9UMR3 T-box transcription factor TBX20 protein 20130413 {GO:0060045=ISS, GO:0035922=IMP, GO:0060577=IMP, GO:0010991=IEA, GO:0003700=IEA, GO:0003180=IMP, GO:0008283=IEA, GO:0008015=IEA, GO:0003215=ISS, GO:0005634=ISS, GO:0009953=ISS, GO:0003143=ISS, GO:0001947=ISS, GO:0005737=ISS, GO:0006936=IEA, GO:0045944=IDA, GO:0001085=ISS, GO:0048370=ISS, GO:0055008=ISS, GO:0001102=ISS, GO:0021524=ISS, GO:0003279=ISS, GO:0001569=IEA, GO:0001706=ISS, GO:0001105=IDA, GO:0000977=IDA, GO:0060413=IMP, GO:0003272=ISS, GO:0003175=ISS, GO:0003203=ISS, GO:0003193=ISS, GO:0036306=IEA, GO:0000122=ISS, GO:0003207=ISS, GO:0003344=ISS, GO:0003148=IMP, GO:0001764=IEA, GO:0045892=ISS} aortic valve morphogenesis, atrial septum morphogenesis, blood circulation, cardiac chamber formation, cardiac muscle tissue morphogenesis, cardiac right ventricle morphogenesis, cardiac septum development, cell proliferation, dorsal/ventral pattern formation, embryonic heart tube elongation, embryonic heart tube morphogenesis, endocardial cushion formation, endocardial cushion morphogenesis, endoderm formation, foramen ovale closure, heart looping, lateral mesoderm formation, muscle contraction, negative regulation of SMAD protein complex assembly, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, neuron migration, outflow tract septum morphogenesis, patterning of blood vessels, pericardium morphogenesis, positive regulation of cardiac muscle cell proliferation, positive regulation of transcription from RNA polymerase II promoter, pulmonary valve formation, pulmonary vein morphogenesis, tricuspid valve development, visceral motor neuron differentiation cytoplasm, nucleus RNA polymerase II activating transcription factor binding, RNA polymerase II regulatory region sequence-specific DNA binding, RNA polymerase II transcription coactivator activity, RNA polymerase II transcription factor binding, sequence-specific DNA binding transcription factor activity Human TBX21 UniProtKB UniProtKB {GO:0006355=PMID:10761931, GO:0003700=PMID:10761931, GO:0044212=PMID:19805038, GO:0030217=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0007275=PMID:10761931, GO:0005634=GO_REF:0000029, GO:0072676=PMID:19805038, GO:0045893=PMID:19805038, GO:0009615=PMID:20583921, GO:0048304=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q9UL17 T-box transcription factor TBX21 protein 20110510 {GO:0006355=TAS, GO:0003700=TAS, GO:0044212=IDA, GO:0030217=IEA, GO:0043025=IEA, GO:0007275=TAS, GO:0005634=NAS, GO:0072676=IDA, GO:0045893=IDA, GO:0009615=IEP, GO:0048304=IEA, GO:0006351=IEA} T cell differentiation, lymphocyte migration, multicellular organismal development, positive regulation of isotype switching to IgG isotypes, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, response to virus, transcription, DNA-dependent neuronal cell body, nucleus sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding Human TBX22 BHF-UCL UniProtKB {GO:0006355=PMID:11024289, GO:0003700=PMID:11024289, GO:0007275=PMID:11024289, GO:0005634=PMID:17846996, GO:0000122=PMID:17846996, GO:0003677=PMID:17846996, GO:0045892=PMID:17846996, GO:0006351=GO_REF:0000037} Q9Y458 T-box transcription factor TBX22 protein 20091029 {GO:0006355=TAS, GO:0003700=TAS, GO:0007275=TAS, GO:0005634=IDA, GO:0000122=IDA, GO:0003677=IDA, GO:0045892=IDA, GO:0006351=IEA} multicellular organismal development, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity Human TBX3 BHF-UCL UniProtKB {GO:0005515=PMID:22002537, GO:0035136=PMID:9207801, GO:0008284=PMID:11689487, GO:0003700=GO_REF:0000019, GO:0060596=GO_REF:0000019, GO:0003167=GO_REF:0000019, GO:0030879=PMID:12116211, GO:0005634=PMID:11689487, GO:0060931=GO_REF:0000019, GO:0045662=PMID:12032820, GO:0001947=GO_REF:0000019, GO:0030539=PMID:12116211, GO:0046884=PMID:12116211, GO:0030857=GO_REF:0000019, GO:0001085=GO_REF:0000024, GO:0009887=PMID:9207801, GO:0060021=GO_REF:0000019, GO:0048332=PMID:9207801, GO:0008595=PMID:9207801, GO:0010159=GO_REF:0000019, GO:0001102=GO_REF:0000024, GO:0043066=PMID:12032820, GO:0001568=GO_REF:0000019, GO:0006357=PMID:9207801, GO:0060412=GO_REF:0000019, GO:0007569=PMID:11689487, GO:2000648=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0045787=PMID:12032820, GO:0001701=GO_REF:0000019, GO:0060923=GO_REF:0000019, GO:0003151=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0043565=PMID:11689487, GO:0001501=PMID:9207801, GO:0032275=PMID:12116211, GO:0021761=GO_REF:0000019, GO:0019827=GO_REF:0000019, GO:0035115=PMID:12116211, GO:0045893=GO_REF:0000019, GO:0030540=PMID:12116211, GO:0045892=PMID:10468588, GO:0060444=GO_REF:0000019, GO:0042733=PMID:12116211, GO:0090398=PMID:22002537} O15119 T-box transcription factor TBX3 protein 20121106 {GO:0005515=IPI, GO:0035136=IDA, GO:0008284=IDA, GO:0003700=IEA, GO:0060596=IEA, GO:0003167=IEA, GO:0030879=IMP, GO:0005634=IDA, GO:0060931=IEA, GO:0045662=IDA, GO:0001947=IEA, GO:0030539=IMP, GO:0046884=IMP, GO:0030857=IEA, GO:0001085=ISS, GO:0009887=IDA, GO:0060021=IEA, GO:0048332=IMP, GO:0008595=IMP, GO:0010159=IEA, GO:0001102=ISS, GO:0043066=IDA, GO:0001568=IEA, GO:0006357=TAS, GO:0060412=IEA, GO:0007569=IDA, GO:2000648=IEA, GO:0000122=IEA, GO:0045787=IDA, GO:0001701=IEA, GO:0060923=IEA, GO:0003151=IEA, GO:0006351=IEA, GO:0043565=IDA, GO:0001501=IMP, GO:0032275=IMP, GO:0021761=IEA, GO:0019827=IEA, GO:0035115=IMP, GO:0045893=IEA, GO:0030540=IMP, GO:0045892=IDA, GO:0060444=IEA, GO:0042733=IMP, GO:0090398=IDA} anterior/posterior axis specification, embryo, atrioventricular bundle cell differentiation, blood vessel development, branching involved in mammary gland duct morphogenesis, cardiac muscle cell fate commitment, cell aging, cellular senescence, embryonic digit morphogenesis, embryonic forelimb morphogenesis, female genitalia development, follicle-stimulating hormone secretion, forelimb morphogenesis, heart looping, in utero embryonic development, limbic system development, luteinizing hormone secretion, male genitalia development, mammary gland development, mammary placode formation, mesoderm morphogenesis, negative regulation of apoptotic process, negative regulation of epithelial cell differentiation, negative regulation of myoblast differentiation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, organ morphogenesis, outflow tract morphogenesis, palate development, positive regulation of cell cycle, positive regulation of cell proliferation, positive regulation of stem cell proliferation, positive regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, sinoatrial node cell development, skeletal system development, specification of organ position, stem cell maintenance, transcription, DNA-dependent, ventricular septum morphogenesis nucleus RNA polymerase II activating transcription factor binding, RNA polymerase II transcription factor binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:P70324 TBX4 UniProtKB UniProtKB {GO:0006355=PMID:10945475, GO:0003700=PMID:10945475, GO:0030324=GO_REF:0000019, GO:0048705=PMID:15106123, GO:0007275=PMID:10945475, GO:0005634=GO_REF:0000039, GO:0030326=GO_REF:0000019, GO:0001525=GO_REF:0000019, GO:0035108=PMID:15106123, GO:0002009=GO_REF:0000019, GO:0003677=PMID:15106123, GO:0006351=GO_REF:0000037} P57082 T-box transcription factor TBX4 protein 20010904 {GO:0006355=NAS, GO:0003700=TAS, GO:0030324=IEA, GO:0048705=IMP, GO:0007275=NAS, GO:0005634=IEA, GO:0030326=IEA, GO:0001525=IEA, GO:0035108=IMP, GO:0002009=IEA, GO:0003677=NAS, GO:0006351=IEA} angiogenesis, embryonic limb morphogenesis, limb morphogenesis, lung development, morphogenesis of an epithelium, multicellular organismal development, regulation of transcription, DNA-dependent, skeletal system morphogenesis, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity Human TBX5 BHF-UCL UniProtKB {GO:0005515=PMID:12845333, GO:0060045=GO_REF:0000019, GO:0010467=Reactome:REACT_71, GO:0007389=GO_REF:0000019, GO:0035136=PMID:8988165, GO:0060044=PMID:11161571, GO:0006367=Reactome:REACT_118713, GO:0008285=PMID:11161571, GO:0003700=PMID:11431700, GO:0003283=GO_REF:0000019, GO:0003181=GO_REF:0000019, GO:0030324=GO_REF:0000019, GO:0007267=PMID:11161571, GO:0003166=GO_REF:0000019, GO:0005634=PMID:12237100, GO:0003281=GO_REF:0000024, GO:0051891=PMID:11431700, GO:0010719=PMID:20299672, GO:0030326=PMID:8988164, GO:0003218=GO_REF:0000024, GO:0007507=PMID:8988165, GO:0005737=PMID:14519429, GO:0045944=PMID:11431700, GO:0055007=GO_REF:0000019, GO:0003229=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0030336=PMID:15138308, GO:0000977=GO_REF:0000019, GO:0003197=GO_REF:0000019, GO:0006917=PMID:12237100, GO:0003677=PMID:16332960, GO:0060039=PMID:15138308, GO:0006351=GO_REF:0000038, GO:0043565=PMID:11431700, GO:0005654=Reactome:REACT_118620, GO:0060980=PMID:20299672, GO:0035115=PMID:16183809, GO:0045893=PMID:11431700, GO:0002009=GO_REF:0000019, GO:0008134=PMID:11431700} Q99593 T-box transcription factor TBX5 protein 20081128 {GO:0005515=IPI, GO:0060045=IEA, GO:0010467=TAS, GO:0007389=IEA, GO:0035136=IMP, GO:0060044=IDA, GO:0006367=TAS, GO:0008285=IDA, GO:0003700=IMP, GO:0003283=IEA, GO:0003181=IEA, GO:0030324=IEA, GO:0007267=IDA, GO:0003166=IEA, GO:0005634=IDA, GO:0003281=ISS, GO:0051891=IDA, GO:0010719=TAS, GO:0030326=IMP, GO:0003218=ISS, GO:0007507=IMP, GO:0005737=IDA, GO:0045944=IMP, GO:0055007=IEA, GO:0003229=IEA, GO:0005667=IEA, GO:0030336=IDA, GO:0000977=IEA, GO:0003197=IEA, GO:0006917=IDA, GO:0003677=IDA, GO:0060039=IDA, GO:0006351=IEA, GO:0043565=IDA, GO:0005654=TAS, GO:0060980=TAS, GO:0035115=IMP, GO:0045893=IDA, GO:0002009=IEA, GO:0008134=IPI} atrial septum development, atrioventricular valve morphogenesis, bundle of His development, cardiac left ventricle formation, cardiac muscle cell differentiation, cell migration involved in coronary vasculogenesis, cell-cell signaling, embryonic forelimb morphogenesis, embryonic limb morphogenesis, endocardial cushion development, forelimb morphogenesis, gene expression, heart development, induction of apoptosis, lung development, morphogenesis of an epithelium, negative regulation of cardiac muscle cell proliferation, negative regulation of cell migration, negative regulation of cell proliferation, negative regulation of epithelial to mesenchymal transition, pattern specification process, pericardium development, positive regulation of cardiac muscle cell proliferation, positive regulation of cardioblast differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, ventricular cardiac muscle tissue development, ventricular septum development cytoplasm, nucleoplasm, nucleus, transcription factor complex DNA binding, RNA polymerase II regulatory region sequence-specific DNA binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding Human TBXA2R Reactome UniProtKB {GO:0005515=PMID:19464661, GO:0005886=Reactome:REACT_22436, GO:0001669=GO_REF:0000019, GO:0007584=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0045777=GO_REF:0000019, GO:0007204=GO_REF:0000019, GO:0045766=GO_REF:0000019, GO:0005085=Reactome:REACT_20567, GO:0006954=GO_REF:0000019, GO:0004960=GO_REF:0000002, GO:0045907=GO_REF:0000019, GO:0007186=PMID:1825698, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:1825698, GO:0045987=GO_REF:0000019, GO:0019932=GO_REF:0000019, GO:0004961=PMID:8119956, GO:0032496=GO_REF:0000019, GO:0016021=GO_REF:0000038} P21731 Thromboxane A2 receptor protein 20090402 {GO:0005515=IPI, GO:0005886=TAS, GO:0001669=IEA, GO:0007584=IEA, GO:0042493=IEA, GO:0030168=TAS, GO:0045777=IEA, GO:0007204=IEA, GO:0045766=IEA, GO:0005085=TAS, GO:0006954=IEA, GO:0004960=IEA, GO:0045907=IEA, GO:0007186=TAS, GO:0007596=TAS, GO:0005887=TAS, GO:0045987=IEA, GO:0019932=IEA, GO:0004961=TAS, GO:0032496=IEA, GO:0016021=IEA} G-protein coupled receptor signaling pathway, blood coagulation, elevation of cytosolic calcium ion concentration, inflammatory response, platelet activation, positive regulation of angiogenesis, positive regulation of blood pressure, positive regulation of smooth muscle contraction, positive regulation of vasoconstriction, response to drug, response to lipopolysaccharide, response to nutrient, second-messenger-mediated signaling acrosomal vesicle, integral to membrane, integral to plasma membrane, plasma membrane guanyl-nucleotide exchange factor activity, protein binding, thromboxane A2 receptor activity, thromboxane receptor activity Human TBXAS1 Reactome UniProtKB {GO:0019371=Reactome:REACT_150149, GO:0019369=Reactome:REACT_147851, GO:0006805=Reactome:REACT_13705, GO:0005506=GO_REF:0000002, GO:0009055=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0006690=Reactome:REACT_13645, GO:0004497=GO_REF:0000037, GO:0030644=GO_REF:0000019, GO:0045907=GO_REF:0000019, GO:0005789=Reactome:REACT_150343, GO:0016705=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0004796=GO_REF:0000003, GO:0020037=GO_REF:0000002} P24557 Thromboxane-A synthase protein 20130301 {GO:0019371=TAS, GO:0019369=TAS, GO:0006805=TAS, GO:0005506=IEA, GO:0009055=IEA, GO:0044281=TAS, GO:0006690=TAS, GO:0004497=IEA, GO:0030644=IEA, GO:0045907=IEA, GO:0005789=TAS, GO:0016705=IEA, GO:0016021=IEA, GO:0004796=IEA, GO:0020037=IEA} arachidonic acid metabolic process, cellular chloride ion homeostasis, cyclooxygenase pathway, icosanoid metabolic process, positive regulation of vasoconstriction, small molecule metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane, integral to membrane electron carrier activity, heme binding, iron ion binding, monooxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, thromboxane-A synthase activity Human TC2N UniProtKB UniProtKB {GO:0005634=GO_REF:0000039} Q8N9U0 Tandem C2 domains nuclear protein protein 20130413 {GO:0005634=IEA} nucleus Human UniProtKB-SubCell:SL-0191 TCAP BHF-UCL UniProtKB {GO:0005515=PMID:15582318, GO:0030240=PMID:9817758, GO:0030018=PMID:9817758, GO:0001756=GO_REF:0000019, GO:0051373=PMID:15582318, GO:0060048=PMID:15582318, GO:0007512=PMID:9817758, GO:0005829=Reactome:REACT_17057, GO:0003300=PMID:15582318, GO:0050982=PMID:17921333, GO:0014898=PMID:12507422, GO:0055003=PMID:9817758, GO:0030674=PMID:15582318, GO:0008307=PMID:9817758, GO:0048769=PMID:9817758, GO:0055008=PMID:9817758, GO:0030049=Reactome:REACT_16969, GO:0030916=GO_REF:0000019, GO:0045214=PMID:9817758, GO:0006950=PMID:17921333, GO:0035995=PMID:12507422, GO:0031432=PMID:15582318, GO:0044325=PMID:11697903, GO:0048739=PMID:9817758, GO:0006461=PMID:9817758, GO:0003009=PMID:9817758, GO:0030241=PMID:9817758, GO:0031674=GO_REF:0000024, GO:0070080=PMID:11846417} O15273 Telethonin protein 20120927 {GO:0005515=IPI, GO:0030240=IMP, GO:0030018=IDA, GO:0001756=IEA, GO:0051373=IPI, GO:0060048=IMP, GO:0007512=IMP, GO:0005829=TAS, GO:0003300=IMP, GO:0050982=TAS, GO:0014898=IMP, GO:0055003=IMP, GO:0030674=IDA, GO:0008307=IMP, GO:0048769=IMP, GO:0055008=IMP, GO:0030049=TAS, GO:0030916=IEA, GO:0045214=IMP, GO:0006950=TAS, GO:0035995=IMP, GO:0031432=IPI, GO:0044325=IPI, GO:0048739=IMP, GO:0006461=TAS, GO:0003009=IEP, GO:0030241=IMP, GO:0031674=ISS, GO:0070080=IPI} adult heart development, cardiac muscle contraction, cardiac muscle fiber development, cardiac muscle hypertrophy, cardiac muscle hypertrophy in response to stress, cardiac muscle tissue morphogenesis, cardiac myofibril assembly, detection of mechanical stimulus, detection of muscle stretch, muscle filament sliding, otic vesicle formation, protein complex assembly, response to stress, sarcomere organization, sarcomerogenesis, skeletal muscle contraction, skeletal muscle myosin thick filament assembly, skeletal muscle thin filament assembly, somitogenesis I band, Z disc, cytosol FATZ binding, ion channel binding, protein binding, protein binding, bridging, structural constituent of muscle, titin Z domain binding, titin binding Human TCEA1 HPA UniProtKB {GO:0005515=PMID:20178742, GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006368=Reactome:REACT_1845, GO:0006366=Reactome:REACT_1366, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003746=GO_REF:0000038, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000002, GO:0050434=Reactome:REACT_6162, GO:0006281=Reactome:REACT_216, GO:0032784=GO_REF:0000002, GO:0006283=Reactome:REACT_1628, GO:0045944=GO_REF:0000019, GO:0030218=GO_REF:0000019, GO:0016032=Reactome:REACT_6256, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_1284, GO:0006289=Reactome:REACT_1826} P23193 Transcription elongation factor A protein 1 protein 20111111 {GO:0005515=IPI, GO:0022415=TAS, GO:0010467=TAS, GO:0006368=TAS, GO:0006366=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0003746=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0050434=TAS, GO:0006281=TAS, GO:0032784=IEA, GO:0006283=TAS, GO:0045944=IEA, GO:0030218=IEA, GO:0016032=TAS, GO:0008270=IEA, GO:0005654=TAS, GO:0006289=TAS} DNA repair, erythrocyte differentiation, gene expression, nucleotide-excision repair, positive regulation of transcription from RNA polymerase II promoter, positive regulation of viral transcription, regulation of DNA-dependent transcription, elongation, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription, DNA-dependent, transcription-coupled nucleotide-excision repair, viral reproduction, viral reproductive process nucleolus, nucleoplasm, nucleus DNA binding, protein binding, translation elongation factor activity, zinc ion binding Human TCEA2 HPA UniProtKB {GO:0005515=PMID:16189514, GO:0005813=GO_REF:0000052, GO:0006354=PMID:8566795, GO:0006357=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003746=GO_REF:0000038, GO:0003677=GO_REF:0000002, GO:0008023=PMID:8566795, GO:0006351=GO_REF:0000002, GO:0032784=GO_REF:0000002, GO:0045944=GO_REF:0000019, GO:0008270=GO_REF:0000002} Q86VL0 Transcription elongation factor A protein 2 protein 20120912 {GO:0005515=IPI, GO:0005813=IDA, GO:0006354=NAS, GO:0006357=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003746=IEA, GO:0003677=IEA, GO:0008023=NAS, GO:0006351=IEA, GO:0032784=IEA, GO:0045944=IEA, GO:0008270=IEA} DNA-dependent transcription, elongation, positive regulation of transcription from RNA polymerase II promoter, regulation of DNA-dependent transcription, elongation, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent centrosome, nucleolus, nucleus, transcription elongation factor complex DNA binding, protein binding, translation elongation factor activity, zinc ion binding Human TCEA3 InterPro UniProtKB {GO:0006357=GO_REF:0000002, GO:0032784=GO_REF:0000002, GO:0005634=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000002} Q5DR83 Rhabdomyosarcoma antigen MU-RMS-40.22 protein 20130413 {GO:0006357=IEA, GO:0032784=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of DNA-dependent transcription, elongation, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human InterPro:IPR003617|InterPro:IPR017923 TCEAL1 PINC UniProtKB {GO:0003700=PMID:7971997, GO:0005634=GO_REF:0000039, GO:0000122=PMID:7971997, GO:0006351=GO_REF:0000037} Q15170 Transcription elongation factor A protein-like 1 protein 20040811 {GO:0003700=NAS, GO:0005634=IEA, GO:0000122=TAS, GO:0006351=IEA} negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus sequence-specific DNA binding transcription factor activity Human TCEAL2 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q9H3H9 Transcription elongation factor A protein-like 2 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus Human UniProtKB-SubCell:SL-0191 TCEAL3 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q969E4 Transcription elongation factor A protein-like 3 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus Human UniProtKB-SubCell:SL-0191 TCEAL4 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q96EI5 Transcription elongation factor A protein-like 4 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus Human UniProtKB-SubCell:SL-0191 TCEAL5 IntAct UniProtKB {GO:0005515=PMID:20195357, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q5H9L2 Transcription elongation factor A protein-like 5 protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0005634=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus protein binding Human UniProtKB:P43354 TCEAL6 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q6IPX3 Transcription elongation factor A protein-like 6 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus Human UniProtKB-SubCell:SL-0191 TCEAL7 UniProtKB UniProtKB {GO:0005634=PMID:18806825, GO:0032088=PMID:19966855, GO:0045892=PMID:18806825, GO:0006351=GO_REF:0000037} Q9BRU2 Transcription elongation factor A protein-like 7 protein 20101220 {GO:0005634=IDA, GO:0032088=IDA, GO:0045892=IDA, GO:0006351=IEA} negative regulation of NF-kappaB transcription factor activity, negative regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus Human TCEAL8 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q8IYN2 Transcription elongation factor A protein-like 8 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus Human UniProtKB-SubCell:SL-0191 TCEANC InterPro UniProtKB {GO:0006357=GO_REF:0000002, GO:0032784=GO_REF:0000002, GO:0005634=GO_REF:0000002, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000002} Q8N8B7 Transcription elongation factor A N-terminal and central domain-containing protein protein 20130413 {GO:0006357=IEA, GO:0032784=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of DNA-dependent transcription, elongation, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding Human InterPro:IPR016492 TCEANC2 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000002} Q96MN5 Transcription elongation factor A N-terminal and central domain-containing protein 2 protein 20130413 {GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} transcription, DNA-dependent nucleus DNA binding Human UniProtKB-SubCell:SL-0191 TCEB1 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0022415=Reactome:REACT_6361, GO:0006511=GO_REF:0000002, GO:0010467=Reactome:REACT_71, GO:0006368=Reactome:REACT_1845, GO:0030891=GO_REF:0000019, GO:0006357=PMID:7660129, GO:0006366=Reactome:REACT_1366, GO:0071456=Reactome:REACT_121311, GO:0061418=Reactome:REACT_120815, GO:0033554=Reactome:REACT_120956, GO:0032403=GO_REF:0000019, GO:0050434=Reactome:REACT_6162, GO:0005829=Reactome:REACT_121002, GO:0019048=GO_REF:0000037, GO:0032968=GO_REF:0000019, GO:0016032=Reactome:REACT_6256, GO:0005654=Reactome:REACT_121374} Q15369 Transcription elongation factor B polypeptide 1 protein 20130415 {GO:0005515=IPI, GO:0022415=TAS, GO:0006511=IEA, GO:0010467=TAS, GO:0006368=TAS, GO:0030891=IEA, GO:0006357=TAS, GO:0006366=TAS, GO:0071456=TAS, GO:0061418=TAS, GO:0033554=TAS, GO:0032403=IEA, GO:0050434=TAS, GO:0005829=TAS, GO:0019048=IEA, GO:0032968=IEA, GO:0016032=TAS, GO:0005654=TAS} cellular response to hypoxia, cellular response to stress, gene expression, positive regulation of transcription elongation from RNA polymerase II promoter, positive regulation of viral transcription, regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter in response to hypoxia, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, ubiquitin-dependent protein catabolic process, viral reproduction, viral reproductive process, virus-host interaction VCB complex, cytosol, nucleoplasm protein binding, protein complex binding Human UniProtKB:P12504 TCEB2 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006368=Reactome:REACT_1845, GO:0016567=GO_REF:0000041, GO:0006366=Reactome:REACT_1366, GO:0071456=Reactome:REACT_121311, GO:0061418=Reactome:REACT_120815, GO:0033554=Reactome:REACT_120956, GO:0003746=GO_REF:0000038, GO:0050434=Reactome:REACT_6162, GO:0005829=Reactome:REACT_121002, GO:0006461=PMID:7660129, GO:0031462=PMID:17636018, GO:0016032=Reactome:REACT_6256, GO:0005654=Reactome:REACT_121374, GO:0031466=PMID:17636018, GO:0031625=PMID:17636018} Q15370 Transcription elongation factor B polypeptide 2 protein 20130415 {GO:0005515=IPI, GO:0022415=TAS, GO:0010467=TAS, GO:0006368=TAS, GO:0016567=IEA, GO:0006366=TAS, GO:0071456=TAS, GO:0061418=TAS, GO:0033554=TAS, GO:0003746=IEA, GO:0050434=TAS, GO:0005829=TAS, GO:0006461=TAS, GO:0031462=IDA, GO:0016032=TAS, GO:0005654=TAS, GO:0031466=IDA, GO:0031625=IDA} cellular response to hypoxia, cellular response to stress, gene expression, positive regulation of viral transcription, protein complex assembly, protein ubiquitination, regulation of transcription from RNA polymerase II promoter in response to hypoxia, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, viral reproduction, viral reproductive process Cul2-RING ubiquitin ligase complex, Cul5-RING ubiquitin ligase complex, cytosol, nucleoplasm protein binding, translation elongation factor activity, ubiquitin protein ligase binding Human UniProtKB:P12504 TCEB3 Reactome UniProtKB {GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0006368=Reactome:REACT_1845, GO:0006366=Reactome:REACT_1366, GO:0006357=PMID:7660129, GO:0016032=Reactome:REACT_6256, GO:0005654=Reactome:REACT_2053, GO:0016021=GO_REF:0000002, GO:0003677=GO_REF:0000002, GO:0050434=Reactome:REACT_6162} Q14241 Transcription elongation factor B polypeptide 3 protein 20130213 {GO:0022415=TAS, GO:0010467=TAS, GO:0006368=TAS, GO:0006366=TAS, GO:0006357=TAS, GO:0016032=TAS, GO:0005654=TAS, GO:0016021=IEA, GO:0003677=IEA, GO:0050434=TAS} gene expression, positive regulation of viral transcription, regulation of transcription from RNA polymerase II promoter, transcription elongation from RNA polymerase II promoter, transcription from RNA polymerase II promoter, viral reproduction, viral reproductive process integral to membrane, nucleoplasm DNA binding Human TCEB3B PINC UniProtKB {GO:0006366=PMID:10692460, GO:0032784=PMID:10692460, GO:0005634=GO_REF:0000039, GO:0016021=GO_REF:0000002, GO:0003677=GO_REF:0000002} Q8IYF1 RNA polymerase II transcription factor SIII subunit A2 protein 20050308 {GO:0006366=TAS, GO:0032784=TAS, GO:0005634=IEA, GO:0016021=IEA, GO:0003677=IEA} regulation of DNA-dependent transcription, elongation, transcription from RNA polymerase II promoter integral to membrane, nucleus DNA binding Human TCEB3C UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0016021=GO_REF:0000002, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q8NG57 RNA polymerase II transcription factor SIII subunit A3 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0016021=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent integral to membrane, nucleus DNA binding Human UniProtKB-SubCell:SL-0191 TCERG1 BHF-UCL UniProtKB {GO:0001103=PMID:20956529, GO:0005515=PMID:15383276, GO:0006366=PMID:9315662, GO:0001106=PMID:20956529, GO:0003713=PMID:9315662, GO:0005634=GO_REF:0000039, GO:0000122=PMID:20956529, GO:0070064=GO_REF:0000019} O14776 Transcription elongation regulator 1 protein 20111213 {GO:0001103=IPI, GO:0005515=IPI, GO:0006366=TAS, GO:0001106=IDA, GO:0003713=TAS, GO:0005634=IEA, GO:0000122=IDA, GO:0070064=IEA} negative regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter nucleus RNA polymerase II repressing transcription factor binding, RNA polymerase II transcription corepressor activity, proline-rich region binding, protein binding, transcription coactivator activity Human TCERG1L null null {} null null null null {} null null null TCF12 BHF-UCL UniProtKB {GO:0005515=PMID:11802795, GO:0005667=GO_REF:0000019, GO:0003700=PMID:11802795, GO:0046982=GO_REF:0000019, GO:0006357=PMID:8163514, GO:0044212=PMID:11802795, GO:0070888=GO_REF:0000019, GO:0005634=GO_REF:0000054, GO:0006351=GO_REF:0000037, GO:0006955=PMID:1312219, GO:0007517=PMID:1312219, GO:0045666=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0045893=GO_REF:0000019} Q99081 Transcription factor 12 protein 20090826 {GO:0005515=IPI, GO:0005667=IEA, GO:0003700=IDA, GO:0046982=IEA, GO:0006357=TAS, GO:0044212=IDA, GO:0070888=IEA, GO:0005634=IDA, GO:0006351=IEA, GO:0006955=TAS, GO:0007517=TAS, GO:0045666=IEA, GO:0046983=IEA, GO:0045893=IEA} immune response, muscle organ development, positive regulation of neuron differentiation, positive regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus, transcription factor complex E-box binding, protein binding, protein dimerization activity, protein heterodimerization activity, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding Human TCF15 PINC UniProtKB {GO:0048339=GO_REF:0000019, GO:0003700=PMID:8041747, GO:0006357=PMID:8825648, GO:0001756=GO_REF:0000019, GO:0016265=GO_REF:0000019, GO:0048705=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0036342=GO_REF:0000019, GO:0043583=GO_REF:0000019, GO:0048644=GO_REF:0000019, GO:0003016=GO_REF:0000019, GO:0050884=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0007498=PMID:8041747, GO:0042755=GO_REF:0000019, GO:0043588=GO_REF:0000019} Q12870 Transcription factor 15 protein 20030904 {GO:0048339=IEA, GO:0003700=TAS, GO:0006357=TAS, GO:0001756=IEA, GO:0016265=IEA, GO:0048705=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0036342=IEA, GO:0043583=IEA, GO:0048644=IEA, GO:0003016=IEA, GO:0050884=IEA, GO:0046983=IEA, GO:0007498=TAS, GO:0042755=IEA, GO:0043588=IEA} death, ear development, eating behavior, mesoderm development, muscle organ morphogenesis, neuromuscular process controlling posture, paraxial mesoderm development, post-anal tail morphogenesis, regulation of transcription from RNA polymerase II promoter, respiratory system process, skeletal system morphogenesis, skin development, somitogenesis, transcription, DNA-dependent nucleus DNA binding, protein dimerization activity, sequence-specific DNA binding transcription factor activity Human TCF19 PINC UniProtKB {GO:0003700=PMID:1868030, GO:0006357=PMID:1868030, GO:0008283=PMID:1868030, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q9Y242 Transcription factor 19 protein 20050308 {GO:0003700=TAS, GO:0006357=TAS, GO:0008283=TAS, GO:0005634=IEA, GO:0008270=IEA, GO:0006351=IEA} cell proliferation, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus sequence-specific DNA binding transcription factor activity, zinc ion binding Human TCF20 UniProtKB UniProtKB {GO:0006355=PMID:10995766, GO:0003713=PMID:10995766, GO:0005634=PMID:10995766, GO:0008270=GO_REF:0000002, GO:0003677=PMID:10995766, GO:0006351=GO_REF:0000037} Q9UGU0 Transcription factor 20 protein 20021106 {GO:0006355=NAS, GO:0003713=NAS, GO:0005634=NAS, GO:0008270=IEA, GO:0003677=NAS, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, transcription coactivator activity, zinc ion binding Human TCF21 BHF-UCL UniProtKB {GO:0001657=GO_REF:0000024, GO:0060426=GO_REF:0000024, GO:0001658=GO_REF:0000024, GO:0042826=GO_REF:0000019, GO:0060425=GO_REF:0000024, GO:0005634=PMID:12493738, GO:0050681=GO_REF:0000024, GO:0048536=GO_REF:0000024, GO:0032835=GO_REF:0000024, GO:0007530=GO_REF:0000024, GO:0048608=GO_REF:0000024, GO:0060008=GO_REF:0000024, GO:0072277=GO_REF:0000024, GO:0060541=GO_REF:0000024, GO:0045944=GO_REF:0000024, GO:0030855=GO_REF:0000024, GO:0046983=GO_REF:0000024, GO:0060021=GO_REF:0000024, GO:0014707=GO_REF:0000024, GO:0060435=GO_REF:0000024, GO:0001944=GO_REF:0000024, GO:0048286=GO_REF:0000024, GO:0001822=GO_REF:0000024, GO:0060766=GO_REF:0000024, GO:0043425=PMID:12493738, GO:0070888=GO_REF:0000024, GO:0000122=PMID:12493738, GO:0001077=GO_REF:0000024, GO:0048557=GO_REF:0000024, GO:0048732=GO_REF:0000024, GO:0060539=GO_REF:0000024, GO:0072162=GO_REF:0000024, GO:0001763=GO_REF:0000024} O43680 Transcription factor 21 protein 20110411 {GO:0001657=ISS, GO:0060426=ISS, GO:0001658=ISS, GO:0042826=IEA, GO:0060425=ISS, GO:0005634=IDA, GO:0050681=ISS, GO:0048536=ISS, GO:0032835=ISS, GO:0007530=ISS, GO:0048608=ISS, GO:0060008=ISS, GO:0072277=ISS, GO:0060541=ISS, GO:0045944=ISS, GO:0030855=ISS, GO:0046983=ISS, GO:0060021=ISS, GO:0014707=ISS, GO:0060435=ISS, GO:0001944=ISS, GO:0048286=ISS, GO:0001822=ISS, GO:0060766=ISS, GO:0043425=IPI, GO:0070888=ISS, GO:0000122=IDA, GO:0001077=ISS, GO:0048557=ISS, GO:0048732=ISS, GO:0060539=ISS, GO:0072162=ISS, GO:0001763=ISS} Sertoli cell differentiation, branching involved in ureteric bud morphogenesis, branchiomeric skeletal muscle development, bronchiole development, diaphragm development, embryonic digestive tract morphogenesis, epithelial cell differentiation, gland development, glomerulus development, kidney development, lung alveolus development, lung morphogenesis, lung vasculature development, metanephric glomerular capillary formation, metanephric mesenchymal cell differentiation, morphogenesis of a branching structure, negative regulation of androgen receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, palate development, positive regulation of transcription from RNA polymerase II promoter, reproductive structure development, respiratory system development, sex determination, spleen development, ureteric bud development, vasculature development nucleus E-box binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, androgen receptor binding, bHLH transcription factor binding, histone deacetylase binding, protein dimerization activity Human UniProtKB:O35437 TCF23 UniProtKB UniProtKB {GO:0007517=GO_REF:0000037, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0030154=GO_REF:0000037} Q7RTU1 Transcription factor 23 protein 20130413 {GO:0007517=IEA, GO:0046983=IEA, GO:0005634=IEA, GO:0030154=IEA} cell differentiation, muscle organ development nucleus protein dimerization activity Human UniProtKB-SubCell:SL-0191 TCF24 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q7RTU0 Transcription factor 24 protein 20130413 {GO:0006355=IEA, GO:0046983=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, protein dimerization activity Human UniProtKB-SubCell:SL-0191 TCF25 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005515=PMID:19060904, GO:0007507=PMID:16574069, GO:0005737=GO_REF:0000052, GO:0003700=PMID:16574069, GO:0005730=GO_REF:0000052, GO:0005634=PMID:16574069, GO:0000122=PMID:16574069, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9H384 Transcription factor 25 protein 20111111 {GO:0005739=IDA, GO:0005515=IPI, GO:0007507=NAS, GO:0005737=IDA, GO:0003700=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0000122=IDA, GO:0003677=IEA, GO:0006351=IEA} heart development, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, mitochondrion, nucleolus, nucleus DNA binding, protein binding, sequence-specific DNA binding transcription factor activity Human TCF3 InterPro UniProtKB {GO:0005515=PMID:10903890, GO:0003700=PMID:2105528, GO:0005634=PMID:10775504, GO:0042803=PMID:14752053, GO:0042692=Reactome:REACT_21303, GO:0051091=PMID:14752053, GO:0048541=GO_REF:0000019, GO:0045944=GO_REF:0000024, GO:0030183=PMID:12435739, GO:0070491=PMID:12493738, GO:0032496=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0001779=GO_REF:0000019, GO:0000788=GO_REF:0000019, GO:0048468=GO_REF:0000019, GO:0002326=PMID:12435739, GO:0005667=PMID:10775504, GO:0033077=GO_REF:0000019, GO:0006355=PMID:2493990, GO:0033152=PMID:16428437, GO:0046982=PMID:10545951, GO:0042493=GO_REF:0000019, GO:0003713=PMID:14752053, GO:0050821=GO_REF:0000019, GO:0043425=PMID:10545951, GO:0031435=PMID:19801649, GO:0070888=GO_REF:0000024, GO:0003677=PMID:2105528, GO:0006351=PMID:10775504, GO:0043565=GO_REF:0000019, GO:0051149=Reactome:REACT_21402, GO:0043966=GO_REF:0000019, GO:0043967=GO_REF:0000019, GO:0045666=GO_REF:0000024, GO:0003682=GO_REF:0000019, GO:0005654=Reactome:REACT_21369, GO:0070644=PMID:17426122, GO:0045893=GO_REF:0000024} Q2TB39 TCF3 protein protein 20130413 {GO:0005515=IPI, GO:0003700=IDA, GO:0005634=IDA, GO:0042803=IDA, GO:0042692=TAS, GO:0051091=IDA, GO:0048541=IEA, GO:0045944=ISS, GO:0030183=NAS, GO:0070491=IPI, GO:0032496=IEA, GO:0046983=IEA, GO:0001779=IEA, GO:0000788=IEA, GO:0048468=IEA, GO:0002326=NAS, GO:0005667=IDA, GO:0033077=IEA, GO:0006355=NAS, GO:0033152=IDA, GO:0046982=IPI, GO:0042493=IEA, GO:0003713=IDA, GO:0050821=IEA, GO:0043425=IPI, GO:0031435=IPI, GO:0070888=ISS, GO:0003677=NAS, GO:0006351=IDA, GO:0043565=IEA, GO:0051149=TAS, GO:0043966=IEA, GO:0043967=IEA, GO:0045666=ISS, GO:0003682=IEA, GO:0005654=TAS, GO:0070644=IDA, GO:0045893=ISS} B cell differentiation, B cell lineage commitment, Peyer's patch development, T cell differentiation in thymus, cell development, histone H3 acetylation, histone H4 acetylation, immunoglobulin V(D)J recombination, muscle cell differentiation, natural killer cell differentiation, positive regulation of muscle cell differentiation, positive regulation of neuron differentiation, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein stabilization, regulation of transcription, DNA-dependent, response to drug, response to lipopolysaccharide, transcription, DNA-dependent nuclear nucleosome, nucleoplasm, nucleus, transcription factor complex DNA binding, E-box binding, bHLH transcription factor binding, chromatin binding, mitogen-activated protein kinase kinase kinase binding, protein binding, protein dimerization activity, protein heterodimerization activity, protein homodimerization activity, repressing transcription factor binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, vitamin D response element binding Human InterPro:IPR011598 TCF4 BHF-UCL UniProtKB {GO:0005515=PMID:10903890, GO:0006352=PMID:8978694, GO:0005667=PMID:8978694, GO:0003700=PMID:11802795, GO:0006367=PMID:8978694, GO:0046982=GO_REF:0000024, GO:0003714=GO_REF:0000019, GO:0001093=PMID:8978694, GO:0005634=PMID:1681116, GO:0070888=PMID:8978694, GO:0000122=GO_REF:0000019, GO:0008022=PMID:10903890, GO:0000978=PMID:8978694, GO:0003677=PMID:16950124, GO:0065004=PMID:8978694, GO:0001087=PMID:8978694, GO:0001077=PMID:8978694, GO:0045666=GO_REF:0000024, GO:0045944=PMID:8978694, GO:0046983=GO_REF:0000002, GO:0045893=PMID:2105528, GO:0001011=PMID:8978694} P15884 Transcription factor 4 protein 20101210 {GO:0005515=IPI, GO:0006352=ISS, GO:0005667=ISS, GO:0003700=IDA, GO:0006367=ISS, GO:0046982=ISS, GO:0003714=IEA, GO:0001093=ISS, GO:0005634=IDA, GO:0070888=ISS, GO:0000122=IEA, GO:0008022=IPI, GO:0000978=ISS, GO:0003677=IDA, GO:0065004=ISS, GO:0001087=ISS, GO:0001077=ISS, GO:0045666=ISS, GO:0045944=ISS, GO:0046983=IEA, GO:0045893=IDA, GO:0001011=ISS} DNA-dependent transcription, initiation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of neuron differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein-DNA complex assembly, transcription initiation from RNA polymerase II promoter nucleus, transcription factor complex DNA binding, E-box binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, TFIIB-class binding transcription factor activity, TFIIB-class transcription factor binding, protein C-terminus binding, protein binding, protein dimerization activity, protein heterodimerization activity, sequence-specific DNA binding RNA polymerase recruiting transcription factor activity, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human UniProtKB:Q60722 TCF7 BHF-UCL UniProtKB {GO:0005515=PMID:9783587, GO:0003700=GO_REF:0000033, GO:0008013=PMID:9488439, GO:0044212=PMID:18579517, GO:0046632=GO_REF:0000019, GO:0048699=GO_REF:0000033, GO:0005634=PMID:18579517, GO:0006955=PMID:1569101, GO:0030538=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0071353=PMID:18579517, GO:0016055=GO_REF:0000033, GO:0060070=GO_REF:0000033, GO:0022008=GO_REF:0000033, GO:0005667=GO_REF:0000033, GO:0006355=GO_REF:0000033, GO:0006357=GO_REF:0000033, GO:0033153=GO_REF:0000019, GO:0042981=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000033, GO:0048557=GO_REF:0000019, GO:0007420=GO_REF:0000033, GO:0003682=GO_REF:0000033, GO:0048619=GO_REF:0000019, GO:0021915=GO_REF:0000019} P36402 Transcription factor 7 protein 20121025 {GO:0005515=IPI, GO:0003700=IBA, GO:0008013=IDA, GO:0044212=IDA, GO:0046632=IEA, GO:0048699=IBA, GO:0005634=IDA, GO:0006955=TAS, GO:0030538=IEA, GO:0042127=IEA, GO:0071353=IDA, GO:0016055=IBA, GO:0060070=IBA, GO:0022008=IBA, GO:0005667=IBA, GO:0006355=IBA, GO:0006357=IBA, GO:0033153=IEA, GO:0042981=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0043565=IBA, GO:0048557=IEA, GO:0007420=IBA, GO:0003682=IBA, GO:0048619=IEA, GO:0021915=IEA} T cell receptor V(D)J recombination, Wnt receptor signaling pathway, alpha-beta T cell differentiation, brain development, canonical Wnt receptor signaling pathway, cellular response to interleukin-4, embryonic digestive tract morphogenesis, embryonic genitalia morphogenesis, embryonic hindgut morphogenesis, generation of neurons, immune response, neural tube development, neurogenesis, regulation of apoptotic process, regulation of cell proliferation, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus, transcription factor complex DNA binding, beta-catenin binding, chromatin binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding Human TCF7L1 UniProtKB UniProtKB {GO:0046022=GO_REF:0000019, GO:0003700=PMID:11085512, GO:0008013=GO_REF:0000033, GO:0044212=GO_REF:0000033, GO:0030111=PMID:11085512, GO:0048699=GO_REF:0000033, GO:0006325=PMID:11085512, GO:0005634=PMID:11085512, GO:0008595=GO_REF:0000019, GO:0016055=GO_REF:0000033, GO:0035019=GO_REF:0000019, GO:0060070=GO_REF:0000033, GO:0022008=GO_REF:0000033, GO:0048319=GO_REF:0000019, GO:0005667=GO_REF:0000033, GO:0006355=PMID:11085512, GO:0006357=GO_REF:0000033, GO:0003677=PMID:11085512, GO:2000036=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000033, GO:0007420=GO_REF:0000033, GO:0003682=GO_REF:0000033, GO:0043588=GO_REF:0000019, GO:0045892=GO_REF:0000019} Q9HCS4 Transcription factor 7-like 1 protein 20010831 {GO:0046022=IEA, GO:0003700=NAS, GO:0008013=IBA, GO:0044212=IBA, GO:0030111=NAS, GO:0048699=IBA, GO:0006325=NAS, GO:0005634=NAS, GO:0008595=IEA, GO:0016055=IBA, GO:0035019=IEA, GO:0060070=IBA, GO:0022008=IBA, GO:0048319=IEA, GO:0005667=IBA, GO:0006355=NAS, GO:0006357=IBA, GO:0003677=NAS, GO:2000036=IEA, GO:0006351=IEA, GO:0043565=IBA, GO:0007420=IBA, GO:0003682=IBA, GO:0043588=IEA, GO:0045892=IEA} Wnt receptor signaling pathway, anterior/posterior axis specification, embryo, axial mesoderm morphogenesis, brain development, canonical Wnt receptor signaling pathway, chromatin organization, generation of neurons, negative regulation of transcription, DNA-dependent, neurogenesis, positive regulation of transcription from RNA polymerase II promoter during mitosis, regulation of Wnt receptor signaling pathway, regulation of stem cell maintenance, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, skin development, somatic stem cell maintenance, transcription, DNA-dependent nucleus, transcription factor complex DNA binding, beta-catenin binding, chromatin binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding Human TCF7L2 BHF-UCL UniProtKB {GO:0005515=PMID:17875931, GO:0000790=PMID:19443654, GO:0003700=PMID:9727977, GO:0008013=PMID:19443654, GO:0044212=PMID:20128911, GO:0045599=GO_REF:0000019, GO:0010909=PMID:15853773, GO:0032993=PMID:14661054, GO:0030538=GO_REF:0000019, GO:0045444=PMID:10937998, GO:0032024=PMID:19386626, GO:0016055=GO_REF:0000002, GO:0001103=PMID:19443654, GO:0050679=GO_REF:0000019, GO:0045295=PMID:14661054, GO:0019901=PMID:16714285, GO:0000122=PMID:12799378, GO:0000978=PMID:19443654, GO:0048641=GO_REF:0000019, GO:0007420=GO_REF:0000033, GO:0043588=GO_REF:0000019, GO:0005654=PMID:19168596, GO:0045892=PMID:15525634, GO:0070016=PMID:12408825, GO:0008134=PMID:16007074, GO:0051897=PMID:19386626, GO:0008283=PMID:12408868, GO:0021983=GO_REF:0000019, GO:0048699=GO_REF:0000033, GO:0035257=PMID:12799378, GO:0005634=PMID:18071026, GO:0030282=GO_REF:0000019, GO:0043433=PMID:12799378, GO:0035411=GO_REF:0000019, GO:0044334=PMID:17072303, GO:0032092=PMID:12799378, GO:0030514=GO_REF:0000019, GO:0046827=PMID:19386626, GO:0045944=PMID:9065401, GO:0042475=GO_REF:0000019, GO:0031641=GO_REF:0000019, GO:0007050=PMID:12408868, GO:0035019=GO_REF:0000019, GO:0090090=PMID:16532032, GO:0060070=PMID:9065401, GO:0048625=PMID:10937998, GO:0022008=GO_REF:0000033, GO:0046621=GO_REF:0000019, GO:0005667=GO_REF:0000033, GO:0043066=PMID:18071026, GO:0043065=GO_REF:0000019, GO:0001568=PMID:15578569, GO:0006357=PMID:9727977, GO:0032350=PMID:15525634, GO:0032252=GO_REF:0000019, GO:0042593=PMID:15525634, GO:0048660=PMID:17122440, GO:0006351=GO_REF:0000037, GO:0043570=PMID:18755497, GO:0009749=PMID:19168596, GO:0043565=PMID:14661054, GO:0048713=GO_REF:0000019, GO:0070369=PMID:9065402, GO:0031016=PMID:18216022, GO:0060325=GO_REF:0000019, GO:0048557=GO_REF:0000019, GO:0014003=GO_REF:0000019, GO:0048619=GO_REF:0000019, GO:0016605=GO_REF:0000039, GO:0003682=GO_REF:0000033, GO:0040037=GO_REF:0000019, GO:0021915=GO_REF:0000019, GO:0061178=GO_REF:0000019} Q9NQB0 Transcription factor 7-like 2 protein 20121203 {GO:0005515=IPI, GO:0000790=IDA, GO:0003700=IDA, GO:0008013=IPI, GO:0044212=IDA, GO:0045599=IEA, GO:0010909=IMP, GO:0032993=IDA, GO:0030538=IEA, GO:0045444=IDA, GO:0032024=IMP, GO:0016055=IEA, GO:0001103=IPI, GO:0050679=IEA, GO:0045295=IPI, GO:0019901=IPI, GO:0000122=IDA, GO:0000978=IDA, GO:0048641=IEA, GO:0007420=IBA, GO:0043588=IEA, GO:0005654=IDA, GO:0045892=IDA, GO:0070016=IPI, GO:0008134=IPI, GO:0051897=IMP, GO:0008283=IMP, GO:0021983=IEA, GO:0048699=IBA, GO:0035257=IPI, GO:0005634=IDA, GO:0030282=IEA, GO:0043433=IDA, GO:0035411=IEA, GO:0044334=IMP, GO:0032092=IDA, GO:0030514=IEA, GO:0046827=IMP, GO:0045944=IDA, GO:0042475=IEA, GO:0031641=IEA, GO:0007050=IMP, GO:0035019=IEA, GO:0090090=IMP, GO:0060070=IC, GO:0048625=IDA, GO:0022008=IBA, GO:0046621=IEA, GO:0005667=IBA, GO:0043066=IDA, GO:0043065=IEA, GO:0001568=IMP, GO:0006357=IDA, GO:0032350=IDA, GO:0032252=IEA, GO:0042593=IDA, GO:0048660=IMP, GO:0006351=IEA, GO:0043570=IMP, GO:0009749=ISS, GO:0043565=IDA, GO:0048713=IEA, GO:0070369=IDA, GO:0031016=TAS, GO:0060325=IEA, GO:0048557=IEA, GO:0014003=IEA, GO:0048619=IEA, GO:0016605=IEA, GO:0003682=IBA, GO:0040037=IEA, GO:0021915=IEA, GO:0061178=IEA} Wnt receptor signaling pathway, blood vessel development, bone mineralization, brain development, canonical Wnt receptor signaling pathway, canonical Wnt receptor signaling pathway involved in positive regulation of epithelial to mesenchymal transition, catenin import into nucleus, cell cycle arrest, cell proliferation, embryonic digestive tract morphogenesis, embryonic genitalia morphogenesis, embryonic hindgut morphogenesis, face morphogenesis, fat cell differentiation, generation of neurons, glucose homeostasis, maintenance of DNA repeat elements, myoblast fate commitment, negative regulation of BMP signaling pathway, negative regulation of apoptotic process, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of fat cell differentiation, negative regulation of fibroblast growth factor receptor signaling pathway, negative regulation of organ growth, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, neural tube development, neurogenesis, odontogenesis of dentin-containing tooth, oligodendrocyte development, pancreas development, pituitary gland development, positive regulation of apoptotic process, positive regulation of epithelial cell proliferation, positive regulation of heparan sulfate proteoglycan biosynthetic process, positive regulation of insulin secretion, positive regulation of protein binding, positive regulation of protein export from nucleus, positive regulation of protein kinase B signaling cascade, positive regulation of transcription from RNA polymerase II promoter, regulation of hormone metabolic process, regulation of insulin secretion involved in cellular response to glucose stimulus, regulation of myelination, regulation of oligodendrocyte differentiation, regulation of skeletal muscle tissue development, regulation of smooth muscle cell proliferation, regulation of transcription from RNA polymerase II promoter, response to glucose stimulus, secretory granule localization, skin development, somatic stem cell maintenance, transcription, DNA-dependent PML body, beta-catenin-TCF7L2 complex, nuclear chromatin, nucleoplasm, nucleus, protein-DNA complex, transcription factor complex RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II repressing transcription factor binding, armadillo repeat domain binding, beta-catenin binding, chromatin binding, gamma-catenin binding, nuclear hormone receptor binding, protein binding, protein kinase binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding Human UniProtKB:P35222 TCFL5 PINC UniProtKB {GO:0006355=PMID:9763657, GO:0003700=PMID:9763657, GO:0006366=PMID:9763657, GO:0042127=PMID:9763657, GO:0046983=GO_REF:0000002, GO:0005634=PMID:9763657, GO:0045595=PMID:9763657, GO:0007275=GO_REF:0000037, GO:0007283=PMID:9763657, GO:0001673=GO_REF:0000019, GO:0003677=PMID:9763657, GO:0030154=GO_REF:0000037} Q9UL49 Transcription factor-like 5 protein protein 20050308 {GO:0006355=IDA, GO:0003700=TAS, GO:0006366=TAS, GO:0042127=IEP, GO:0046983=IEA, GO:0005634=IDA, GO:0045595=IEP, GO:0007275=IEA, GO:0007283=IEP, GO:0001673=IEA, GO:0003677=IDA, GO:0030154=IEA} cell differentiation, multicellular organismal development, regulation of cell differentiation, regulation of cell proliferation, regulation of transcription, DNA-dependent, spermatogenesis, transcription from RNA polymerase II promoter male germ cell nucleus, nucleus DNA binding, protein dimerization activity, sequence-specific DNA binding transcription factor activity Human TCHH HPA UniProtKB {GO:0008150=GO_REF:0000015, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005509=PMID:7685034, GO:0031424=GO_REF:0000037, GO:0045111=GO_REF:0000052, GO:0005856=PMID:7686953} Q07283 Trichohyalin protein 20111111 {GO:0008150=ND, GO:0005813=IDA, GO:0005737=IDA, GO:0005886=IDA, GO:0005509=TAS, GO:0031424=IEA, GO:0045111=IDA, GO:0005856=NAS} biological_process, keratinization centrosome, cytoplasm, cytoskeleton, intermediate filament cytoskeleton, plasma membrane calcium ion binding Human TCHHL1 InterPro UniProtKB {GO:0005509=GO_REF:0000002} Q5QJ38 Trichohyalin-like protein 1 protein 20130413 {GO:0005509=IEA} calcium ion binding Human InterPro:IPR011992 TCHP HPA UniProtKB {GO:0005515=PMID:15731013, GO:0005739=PMID:18931701, GO:0005813=GO_REF:0000052, GO:0030308=PMID:18931701, GO:0005737=GO_REF:0000052, GO:0045179=PMID:15731013, GO:0005886=GO_REF:0000052, GO:0006915=PMID:18931701, GO:0045095=PMID:15731013} Q9BT92 Trichoplein keratin filament-binding protein protein 20110516 {GO:0005515=IPI, GO:0005739=IDA, GO:0005813=IDA, GO:0030308=IDA, GO:0005737=IDA, GO:0045179=IDA, GO:0005886=IDA, GO:0006915=IDA, GO:0045095=IDA} apoptotic process, negative regulation of cell growth apical cortex, centrosome, cytoplasm, keratin filament, mitochondrion, plasma membrane protein binding Human TCIRG1 InterPro UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005215=PMID:8579597, GO:0008284=PMID:9806637, GO:0051701=Reactome:REACT_121237, GO:0005886=PMID:9806637, GO:0015078=GO_REF:0000002, GO:0055085=Reactome:REACT_15518, GO:0005739=GO_REF:0000019, GO:0000220=GO_REF:0000002, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0016324=PMID:15800125, GO:0006968=PMID:9806637, GO:0005887=PMID:10329006, GO:0030670=Reactome:REACT_121163, GO:0015991=GO_REF:0000002, GO:0090382=Reactome:REACT_121256, GO:0010008=Reactome:REACT_25268, GO:0033179=GO_REF:0000002, GO:0015992=PMID:8579597} Q8TCH1 T-cell immune regulator 1 transcript variant 3 protein 20130413 {GO:0008286=TAS, GO:0005215=TAS, GO:0008284=TAS, GO:0051701=TAS, GO:0005886=TAS, GO:0015078=IEA, GO:0055085=TAS, GO:0005739=IEA, GO:0000220=IEA, GO:0006879=TAS, GO:0033572=TAS, GO:0016324=IDA, GO:0006968=TAS, GO:0005887=TAS, GO:0030670=TAS, GO:0015991=IEA, GO:0090382=TAS, GO:0010008=TAS, GO:0033179=IEA, GO:0015992=TAS} ATP hydrolysis coupled proton transport, cellular defense response, cellular iron ion homeostasis, insulin receptor signaling pathway, interaction with host, phagosome maturation, positive regulation of cell proliferation, proton transport, transferrin transport, transmembrane transport apical plasma membrane, endosome membrane, integral to plasma membrane, mitochondrion, phagocytic vesicle membrane, plasma membrane, proton-transporting V-type ATPase, V0 domain, vacuolar proton-transporting V-type ATPase, V0 domain hydrogen ion transmembrane transporter activity, transporter activity Human InterPro:IPR002490 TCL1A PINC UniProtKB {GO:0005515=PMID:16934922, GO:0005783=GO_REF:0000039, GO:0019827=GO_REF:0000019, GO:0007275=PMID:7809072, GO:0045120=GO_REF:0000019, GO:0005938=GO_REF:0000019} P56279 T-cell leukemia/lymphoma protein 1A protein 20030904 {GO:0005515=IPI, GO:0005783=IEA, GO:0019827=IEA, GO:0007275=TAS, GO:0045120=IEA, GO:0005938=IEA} multicellular organismal development, stem cell maintenance cell cortex, endoplasmic reticulum, pronucleus protein binding Human TCL1B null null {} null null null null {} null null null TCN1 RefGenome UniProtKB {GO:0015889=GO_REF:0000002, GO:0009235=GO_REF:0000033, GO:0031419=GO_REF:0000033, GO:0005576=GO_REF:0000039, GO:0006824=GO_REF:0000037} P20061 Transcobalamin-1 protein 20110131 {GO:0015889=IEA, GO:0009235=IBA, GO:0031419=IBA, GO:0005576=IEA, GO:0006824=IEA} cobalamin metabolic process, cobalamin transport, cobalt ion transport extracellular region cobalamin binding Human PANTHER:PTN000059409 TCN2 PINC UniProtKB {GO:0015889=GO_REF:0000002, GO:0009235=GO_REF:0000033, GO:0031419=PMID:16537422, GO:0005615=PMID:1708393, GO:0046872=GO_REF:0000037, GO:0006824=GO_REF:0000037} P20062 Transcobalamin-2 protein 20030904 {GO:0015889=IEA, GO:0009235=IBA, GO:0031419=IDA, GO:0005615=TAS, GO:0046872=IEA, GO:0006824=IEA} cobalamin metabolic process, cobalamin transport, cobalt ion transport extracellular space cobalamin binding, metal ion binding Human TCOF1 HPA UniProtKB {GO:0005515=PMID:17620599, GO:0005215=PMID:9096354, GO:0001501=PMID:9096354, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0042790=GO_REF:0000019} Q13428 Treacle protein protein 20111111 {GO:0005515=IPI, GO:0005215=TAS, GO:0001501=TAS, GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0042790=IEA} skeletal system development, transcription of nuclear large rRNA transcript from RNA polymerase I promoter cytoplasm, nucleolus, nucleus protein binding, transporter activity Human TCP1 HPA UniProtKB {GO:0005813=PMID:20080638, GO:0005794=GO_REF:0000052, GO:0030054=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005832=GO_REF:0000019, GO:0005874=PMID:21525035, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_16980, GO:0005720=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0006457=Reactome:REACT_17004, GO:0007021=PMID:11532003, GO:0051084=Reactome:REACT_16952, GO:0051082=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0000242=GO_REF:0000019} P17987 T-complex protein 1 subunit alpha protein 20101115 {GO:0005813=IDA, GO:0005794=IDA, GO:0030054=IDA, GO:0005886=IDA, GO:0005832=IEA, GO:0005874=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0005524=IEA, GO:0005829=TAS, GO:0005720=IEA, GO:0005737=IDA, GO:0006457=TAS, GO:0007021=NAS, GO:0051084=TAS, GO:0051082=IEA, GO:0044267=TAS, GO:0000242=IEA} 'de novo' posttranslational protein folding, cellular protein metabolic process, protein folding, tubulin complex assembly Golgi apparatus, cell junction, centrosome, chaperonin-containing T-complex, cytoplasm, cytosol, microtubule, nuclear heterochromatin, nucleolus, nucleus, pericentriolar material, plasma membrane ATP binding, unfolded protein binding Human TCP10 PINC UniProtKB {GO:0005829=PMID:8111376} Q12799 T-complex protein 10A homolog protein 20030904 {GO:0005829=TAS} cytosol Human TCP10L UniProtKB UniProtKB {GO:0005634=GO_REF:0000039} Q8TDR4 T-complex protein 10A homolog 2 protein 20130413 {GO:0005634=IEA} nucleus Human UniProtKB-SubCell:SL-0191 TCP11 UniProtKB UniProtKB {GO:0007275=PMID:1893875, GO:0016021=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q8WWU5 T-complex protein 11 homolog protein 20090630 {GO:0007275=TAS, GO:0016021=IEA, GO:0007283=IEA, GO:0030154=IEA} cell differentiation, multicellular organismal development, spermatogenesis integral to membrane Human TCP11L1 UniProtKB UniProtKB {GO:0005874=PMID:21525035} Q9NUJ3 T-complex protein 11-like protein 1 protein 20120601 {GO:0005874=IDA} microtubule Human TCP11L2 null null {} null null null null {} null null null TCTA UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} P57738 T-cell leukemia translocation-altered gene protein protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TCTE3 UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0003774=GO_REF:0000037, GO:0016020=GO_REF:0000039, GO:0030286=GO_REF:0000037, GO:0005874=GO_REF:0000037, GO:0006810=GO_REF:0000037} Q8IZS6 Tctex1 domain-containing protein 3 protein 20130413 {GO:0005737=IEA, GO:0003774=IEA, GO:0016020=IEA, GO:0030286=IEA, GO:0005874=IEA, GO:0006810=IEA} transport cytoplasm, dynein complex, membrane, microtubule motor activity Human UniProtKB-SubCell:SL-0162 TCTEX1D2 IntAct UniProtKB {GO:0005515=PMID:20195357} Q8WW35 Tctex1 domain-containing protein 2 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:P13984 TCTEX1D4 IntAct UniProtKB {GO:0005515=PMID:21382349} Q5JR98 Tctex1 domain-containing protein 4 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:P36873-2 TCTN2 UniProtKB UniProtKB {GO:0042384=GO_REF:0000024, GO:0005737=GO_REF:0000037, GO:0060271=GO_REF:0000024, GO:0036038=GO_REF:0000024, GO:0005932=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0007224=GO_REF:0000024} Q96GX1 Tectonic-2 protein 20110616 {GO:0042384=ISS, GO:0005737=IEA, GO:0060271=ISS, GO:0036038=ISS, GO:0005932=IEA, GO:0016021=IEA, GO:0007224=ISS} cilium assembly, cilium morphogenesis, smoothened signaling pathway TCTN-B9D complex, cytoplasm, integral to membrane, microtubule basal body Human UniProtKB:Q2MV57 TCTN3 UniProtKB UniProtKB {GO:0060271=GO_REF:0000024, GO:0006915=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0007224=PMID:22883145} Q6NUS6 Tectonic-3 protein 20120925 {GO:0060271=ISS, GO:0006915=IEA, GO:0016021=IEA, GO:0007224=IMP} apoptotic process, cilium morphogenesis, smoothened signaling pathway integral to membrane Human TDG IntAct UniProtKB {GO:0005515=PMID:21722948, GO:0032091=GO_REF:0000019, GO:0030983=PMID:22573813, GO:0005634=PMID:8662714, GO:0009790=GO_REF:0000024, GO:0035562=GO_REF:0000019, GO:0042803=PMID:22327402, GO:0003690=PMID:22327402, GO:0080111=GO_REF:0000024, GO:0006298=PMID:22573813, GO:0008263=PMID:8662714, GO:0032183=GO_REF:0000019, GO:0001104=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0016799=GO_REF:0000002, GO:0003684=PMID:9489705, GO:0019104=PMID:21862836, GO:0006281=Reactome:REACT_216, GO:0006284=Reactome:REACT_1104, GO:0016605=GO_REF:0000019, GO:0043566=GO_REF:0000024, GO:0006285=Reactome:REACT_804, GO:0045008=Reactome:REACT_2156, GO:0040029=GO_REF:0000024, GO:0005654=Reactome:REACT_1674, GO:0016568=GO_REF:0000037} Q13569 G/T mismatch-specific thymine DNA glycosylase protein 20130415 {GO:0005515=IPI, GO:0032091=IEA, GO:0030983=IDA, GO:0005634=IDA, GO:0009790=ISS, GO:0035562=IEA, GO:0042803=IDA, GO:0003690=IDA, GO:0080111=ISS, GO:0006298=IDA, GO:0008263=IDA, GO:0032183=IEA, GO:0001104=IEA, GO:0000122=IEA, GO:0016799=IEA, GO:0003684=TAS, GO:0019104=IDA, GO:0006281=TAS, GO:0006284=TAS, GO:0016605=IEA, GO:0043566=ISS, GO:0006285=TAS, GO:0045008=TAS, GO:0040029=ISS, GO:0005654=TAS, GO:0016568=IEA} DNA demethylation, DNA repair, base-excision repair, base-excision repair, AP site formation, chromatin modification, depyrimidination, embryo development, mismatch repair, negative regulation of chromatin binding, negative regulation of protein binding, negative regulation of transcription from RNA polymerase II promoter, regulation of gene expression, epigenetic PML body, nucleoplasm, nucleus DNA N-glycosylase activity, RNA polymerase II transcription cofactor activity, SUMO binding, damaged DNA binding, double-stranded DNA binding, hydrolase activity, hydrolyzing N-glycosyl compounds, mismatched DNA binding, protein binding, protein homodimerization activity, pyrimidine-specific mismatch base pair DNA N-glycosylase activity, structure-specific DNA binding Human UniProtKB:Q9GZX7 TDGF1 MGI UniProtKB {GO:0005515=PMID:12919325, GO:0008284=PMID:8006041, GO:0048471=GO_REF:0000019, GO:0007369=GO_REF:0000019, GO:0002042=PMID:17720976, GO:0050731=PMID:10493495, GO:0030879=PMID:11857442, GO:0005634=GO_REF:0000019, GO:0009790=PMID:11857442, GO:0048146=GO_REF:0000019, GO:0031225=GO_REF:0000037, GO:0005615=PMID:17720976, GO:0030154=PMID:11857442, GO:0007507=PMID:9576836, GO:0000187=PMID:9013573, GO:0007173=PMID:8006041, GO:0018105=PMID:10493495, GO:0035729=PMID:17720976, GO:0045944=GO_REF:0000019, GO:0071356=PMID:17720976, GO:0071354=PMID:17720976, GO:0008595=GO_REF:0000024, GO:0055007=GO_REF:0000019, GO:0060070=GO_REF:0000019, GO:0030512=GO_REF:0000019, GO:0030334=GO_REF:0000019, GO:0043066=PMID:10493495, GO:0005794=GO_REF:0000019, GO:0030335=PMID:12649175, GO:0009986=PMID:12925698, GO:0005102=PMID:11909953, GO:0009966=PMID:12649175, GO:0030509=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0044344=PMID:17720976, GO:0071346=PMID:17720976, GO:0071364=PMID:17720976, GO:0045121=PMID:17720976, GO:0008083=PMID:8006041, GO:0001570=GO_REF:0000019, GO:0001954=GO_REF:0000019, GO:0019897=GO_REF:0000024, GO:0001763=PMID:10070255} P13385 Teratocarcinoma-derived growth factor 1 protein 20020717 {GO:0005515=IPI, GO:0008284=IDA, GO:0048471=IEA, GO:0007369=IEA, GO:0002042=IMP, GO:0050731=IDA, GO:0030879=TAS, GO:0005634=IEA, GO:0009790=TAS, GO:0048146=IEA, GO:0031225=IEA, GO:0005615=IDA, GO:0030154=TAS, GO:0007507=IDA, GO:0000187=IDA, GO:0007173=IDA, GO:0018105=IDA, GO:0035729=IDA, GO:0045944=IEA, GO:0071356=IDA, GO:0071354=IDA, GO:0008595=ISS, GO:0055007=IEA, GO:0060070=IEA, GO:0030512=IEA, GO:0030334=IEA, GO:0043066=IDA, GO:0005794=IEA, GO:0030335=IDA, GO:0009986=IDA, GO:0005102=IDA, GO:0009966=IDA, GO:0030509=IEA, GO:0001701=IEA, GO:0044344=IDA, GO:0071346=IDA, GO:0071364=IDA, GO:0045121=IDA, GO:0008083=IDA, GO:0001570=IEA, GO:0001954=IEA, GO:0019897=ISS, GO:0001763=TAS} BMP signaling pathway, activation of MAPK activity, anterior/posterior axis specification, embryo, canonical Wnt receptor signaling pathway, cardiac muscle cell differentiation, cell differentiation, cell migration involved in sprouting angiogenesis, cellular response to epidermal growth factor stimulus, cellular response to fibroblast growth factor stimulus, cellular response to hepatocyte growth factor stimulus, cellular response to interferon-gamma, cellular response to interleukin-6, cellular response to tumor necrosis factor, embryo development, epidermal growth factor receptor signaling pathway, gastrulation, heart development, in utero embryonic development, mammary gland development, morphogenesis of a branching structure, negative regulation of apoptotic process, negative regulation of transforming growth factor beta receptor signaling pathway, peptidyl-serine phosphorylation, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of cell-matrix adhesion, positive regulation of fibroblast proliferation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of transcription from RNA polymerase II promoter, regulation of cell migration, regulation of signal transduction, vasculogenesis Golgi apparatus, anchored to membrane, cell surface, extracellular space, extrinsic to plasma membrane, membrane raft, nucleus, perinuclear region of cytoplasm growth factor activity, protein binding, receptor binding Human TDO2 Reactome UniProtKB {GO:0034641=Reactome:REACT_13, GO:0006569=Reactome:REACT_916, GO:0004833=Reactome:REACT_1007, GO:0019825=GO_REF:0000019, GO:0019441=GO_REF:0000041, GO:0044281=Reactome:REACT_111217, GO:0019442=GO_REF:0000033, GO:0016597=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_1007, GO:0020037=GO_REF:0000033} P48775 Tryptophan 2,3-dioxygenase protein 20130213 {GO:0034641=TAS, GO:0006569=TAS, GO:0004833=TAS, GO:0019825=IEA, GO:0019441=IEA, GO:0044281=TAS, GO:0019442=IBA, GO:0016597=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0020037=IBA} cellular nitrogen compound metabolic process, small molecule metabolic process, tryptophan catabolic process, tryptophan catabolic process to acetyl-CoA, tryptophan catabolic process to kynurenine cytosol amino acid binding, heme binding, metal ion binding, oxygen binding, tryptophan 2,3-dioxygenase activity Human TDP1 UniProtKB UniProtKB {GO:0005515=PMID:15744309, GO:0008219=GO_REF:0000037, GO:0000012=PMID:15811850, GO:0005737=PMID:17948061, GO:0004527=GO_REF:0000037, GO:0008081=GO_REF:0000002, GO:0003690=PMID:15811850, GO:0006281=PMID:17948061, GO:0003697=PMID:15811850, GO:0005634=GO_REF:0000039, GO:0017005=PMID:22822062, GO:0006302=PMID:12023295} Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 protein 20120920 {GO:0005515=IPI, GO:0008219=IEA, GO:0000012=IDA, GO:0005737=IDA, GO:0004527=IEA, GO:0008081=IEA, GO:0003690=IDA, GO:0006281=IDA, GO:0003697=IDA, GO:0005634=IEA, GO:0017005=IDA, GO:0006302=IDA} DNA repair, cell death, double-strand break repair, single strand break repair cytoplasm, nucleus 3'-tyrosyl-DNA phosphodiesterase activity, double-stranded DNA binding, exonuclease activity, phosphoric diester hydrolase activity, protein binding, single-stranded DNA binding Human TDP2 UniProtKB UniProtKB {GO:0005515=PMID:18039968, GO:0030145=PMID:22822062, GO:0000287=PMID:22822062, GO:0070260=PMID:22822062, GO:0003714=PMID:10764746, GO:0005730=GO_REF:0000039, GO:0005634=PMID:22908287, GO:0036317=PMID:22908287, GO:0006302=PMID:21030584, GO:0004518=GO_REF:0000037, GO:0005737=PMID:22908287, GO:0003697=PMID:22822062, GO:0016605=PMID:19794497, GO:0007166=PMID:10764746} O95551 Tyrosyl-DNA phosphodiesterase 2 protein 20120920 {GO:0005515=IPI, GO:0030145=IDA, GO:0000287=IDA, GO:0070260=IDA, GO:0003714=TAS, GO:0005730=IEA, GO:0005634=IDA, GO:0036317=IDA, GO:0006302=IMP, GO:0004518=IEA, GO:0005737=IDA, GO:0003697=IDA, GO:0016605=IDA, GO:0007166=TAS} cell surface receptor signaling pathway, double-strand break repair PML body, cytoplasm, nucleolus, nucleus 5'-tyrosyl-DNA phosphodiesterase activity, magnesium ion binding, manganese ion binding, nuclease activity, protein binding, single-stranded DNA binding, transcription corepressor activity, tyrosyl-RNA phosphodiesterase activity Human TDRD1 UniProtKB UniProtKB {GO:0033391=GO_REF:0000019, GO:0005737=GO_REF:0000024, GO:0007126=GO_REF:0000037, GO:0034587=GO_REF:0000024, GO:0071546=GO_REF:0000024, GO:0007275=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0031047=GO_REF:0000024, GO:0007283=GO_REF:0000024, GO:0043186=GO_REF:0000024, GO:0007281=GO_REF:0000024, GO:0043046=GO_REF:0000024} Q9BXT4 Tudor domain-containing protein 1 protein 20100114 {GO:0033391=IEA, GO:0005737=ISS, GO:0007126=IEA, GO:0034587=ISS, GO:0071546=ISS, GO:0007275=IEA, GO:0008270=IEA, GO:0031047=ISS, GO:0007283=ISS, GO:0043186=ISS, GO:0007281=ISS, GO:0043046=ISS} DNA methylation involved in gamete generation, gene silencing by RNA, germ cell development, meiosis, multicellular organismal development, piRNA metabolic process, spermatogenesis P granule, chromatoid body, cytoplasm, pi-body zinc ion binding Human UniProtKB:Q99MV1 TDRD3 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0003682=PMID:21172665, GO:0003713=PMID:21172665, GO:0005634=PMID:21172665, GO:0035064=PMID:21172665, GO:0016568=GO_REF:0000037} Q9H7E2 Tudor domain-containing protein 3 protein 20110121 {GO:0005737=IEA, GO:0003682=IDA, GO:0003713=IDA, GO:0005634=IDA, GO:0035064=IDA, GO:0016568=IEA} chromatin modification cytoplasm, nucleus chromatin binding, methylated histone residue binding, transcription coactivator activity Human TDRD6 UniProtKB UniProtKB {GO:0033391=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0005783=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000024, GO:0043186=GO_REF:0000019, GO:0007281=GO_REF:0000019} O60522 Tudor domain-containing protein 6 protein 20091016 {GO:0033391=ISS, GO:0005737=ISS, GO:0005783=IEA, GO:0007275=IEA, GO:0007283=ISS, GO:0043186=IEA, GO:0007281=IEA} germ cell development, multicellular organismal development, spermatogenesis P granule, chromatoid body, cytoplasm, endoplasmic reticulum Human UniProtKB:P61407 TDRD7 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0070306=PMID:21436445, GO:0007283=GO_REF:0000024, GO:0003729=PMID:21436445, GO:0007281=GO_REF:0000019, GO:0033391=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0010608=PMID:21436445, GO:0047485=GO_REF:0000019, GO:0002089=PMID:21436445, GO:0005759=GO_REF:0000019, GO:0035770=PMID:21436445, GO:0043186=GO_REF:0000019} Q8NHU6 Tudor domain-containing protein 7 protein 20130415 {GO:0005515=IPI, GO:0070306=IMP, GO:0007283=ISS, GO:0003729=IDA, GO:0007281=IEA, GO:0033391=ISS, GO:0005737=ISS, GO:0010608=IMP, GO:0047485=IEA, GO:0002089=IMP, GO:0005759=IEA, GO:0035770=IDA, GO:0043186=IEA} germ cell development, lens fiber cell differentiation, lens morphogenesis in camera-type eye, posttranscriptional regulation of gene expression, spermatogenesis P granule, chromatoid body, cytoplasm, mitochondrial matrix, ribonucleoprotein granule mRNA binding, protein N-terminus binding, protein binding Human UniProtKB:P42771 TDRD9 UniProtKB UniProtKB {GO:0008026=GO_REF:0000002, GO:0004386=GO_REF:0000002, GO:0007275=GO_REF:0000037, GO:0005634=GO_REF:0000024, GO:0031047=GO_REF:0000037, GO:0007283=GO_REF:0000024, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0009566=GO_REF:0000024, GO:0034587=GO_REF:0000024, GO:0071547=GO_REF:0000024, GO:0007140=GO_REF:0000024, GO:0043046=GO_REF:0000024} Q8NDG6 Putative ATP-dependent RNA helicase TDRD9 protein 20100114 {GO:0008026=IEA, GO:0004386=IEA, GO:0007275=IEA, GO:0005634=ISS, GO:0031047=IEA, GO:0007283=ISS, GO:0003676=IEA, GO:0005524=IEA, GO:0030154=IEA, GO:0009566=ISS, GO:0034587=ISS, GO:0071547=ISS, GO:0007140=ISS, GO:0043046=ISS} DNA methylation involved in gamete generation, cell differentiation, fertilization, gene silencing by RNA, male meiosis, multicellular organismal development, piRNA metabolic process, spermatogenesis nucleus, piP-body ATP binding, ATP-dependent helicase activity, helicase activity, nucleic acid binding Human UniProtKB:Q14BI7 TDRKH ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0003723=GO_REF:0000037} Q9Y2W6 Tudor and KH domain-containing protein protein 20130413 {GO:0005739=IEA, GO:0003723=IEA} mitochondrion RNA binding Human Ensembl:ENSMUSP00000129635 TEAD1 IntAct UniProtKB {GO:0005515=PMID:22863277, GO:0010467=Reactome:REACT_71, GO:0048339=GO_REF:0000019, GO:0003700=PMID:19324877, GO:0006367=Reactome:REACT_118713, GO:0005634=GO_REF:0000002, GO:0035329=PMID:19324877, GO:0003677=GO_REF:0000037, GO:0003143=GO_REF:0000019, GO:0048368=GO_REF:0000019, GO:0042127=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0005654=Reactome:REACT_118835, GO:0030903=GO_REF:0000019} P28347 Transcriptional enhancer factor TEF-1 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0048339=IEA, GO:0003700=IDA, GO:0006367=TAS, GO:0005634=IEA, GO:0035329=IDA, GO:0003677=IEA, GO:0003143=IEA, GO:0048368=IEA, GO:0042127=IEA, GO:0045944=IEA, GO:0005654=TAS, GO:0030903=IEA} embryonic heart tube morphogenesis, gene expression, hippo signaling cascade, lateral mesoderm development, notochord development, paraxial mesoderm development, positive regulation of transcription from RNA polymerase II promoter, regulation of cell proliferation, transcription initiation from RNA polymerase II promoter nucleoplasm, nucleus DNA binding, protein binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:P46937 TEAD2 Reactome UniProtKB {GO:0005515=PMID:19324877, GO:0010467=Reactome:REACT_71, GO:0005667=GO_REF:0000019, GO:0006355=PMID:8702974, GO:0048339=GO_REF:0000019, GO:0006367=Reactome:REACT_118713, GO:0003700=PMID:19324877, GO:0003705=GO_REF:0000019, GO:0001843=GO_REF:0000019, GO:0005634=PMID:8702974, GO:0035329=PMID:19324877, GO:0003677=GO_REF:0000019, GO:0003143=GO_REF:0000019, GO:0048368=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0060548=GO_REF:0000019, GO:0005654=Reactome:REACT_118835, GO:0030903=GO_REF:0000019, GO:0001570=GO_REF:0000019} Q15562 Transcriptional enhancer factor TEF-4 protein 20130301 {GO:0005515=IPI, GO:0010467=TAS, GO:0005667=IEA, GO:0006355=NAS, GO:0048339=IEA, GO:0006367=TAS, GO:0003700=IDA, GO:0003705=IEA, GO:0001843=IEA, GO:0005634=NAS, GO:0035329=IDA, GO:0003677=IEA, GO:0003143=IEA, GO:0048368=IEA, GO:0045944=IEA, GO:0060548=IEA, GO:0005654=TAS, GO:0030903=IEA, GO:0001570=IEA} embryonic heart tube morphogenesis, gene expression, hippo signaling cascade, lateral mesoderm development, negative regulation of cell death, neural tube closure, notochord development, paraxial mesoderm development, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription initiation from RNA polymerase II promoter, vasculogenesis nucleoplasm, nucleus, transcription factor complex DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, protein binding, sequence-specific DNA binding transcription factor activity Human TEAD3 HPA UniProtKB {GO:0005515=PMID:19324877, GO:0010467=Reactome:REACT_71, GO:0005667=GO_REF:0000019, GO:0007565=PMID:9148898, GO:0006367=Reactome:REACT_118713, GO:0003700=PMID:19324877, GO:0006357=PMID:9148898, GO:0045944=GO_REF:0000019, GO:0005654=Reactome:REACT_118835, GO:0005634=GO_REF:0000052, GO:0035329=PMID:19324877, GO:0003677=GO_REF:0000019} Q99594 Transcriptional enhancer factor TEF-5 protein 20101115 {GO:0005515=IPI, GO:0010467=TAS, GO:0005667=IEA, GO:0007565=TAS, GO:0006367=TAS, GO:0003700=IDA, GO:0006357=TAS, GO:0045944=IEA, GO:0005654=TAS, GO:0005634=IDA, GO:0035329=IDA, GO:0003677=IEA} female pregnancy, gene expression, hippo signaling cascade, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter nucleoplasm, nucleus, transcription factor complex DNA binding, protein binding, sequence-specific DNA binding transcription factor activity Human TEAD4 ENSEMBL UniProtKB {GO:0001830=GO_REF:0000019, GO:0005515=PMID:20972459, GO:0010467=Reactome:REACT_71, GO:0005667=GO_REF:0000019, GO:0006367=Reactome:REACT_118713, GO:0003700=GO_REF:0000002, GO:0001708=GO_REF:0000019, GO:0006357=PMID:8921372, GO:0007566=GO_REF:0000019, GO:0005634=GO_REF:0000002, GO:0035329=GO_REF:0000002, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000002, GO:0001501=PMID:8662936, GO:0007517=PMID:8921372, GO:0045944=GO_REF:0000019, GO:0005654=Reactome:REACT_118835} Q53GI4 Transcriptional enhancer factor TEF-3 protein 20130413 {GO:0001830=IEA, GO:0005515=IPI, GO:0010467=TAS, GO:0005667=IEA, GO:0006367=TAS, GO:0003700=IEA, GO:0001708=IEA, GO:0006357=TAS, GO:0007566=IEA, GO:0005634=IEA, GO:0035329=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0001501=TAS, GO:0007517=TAS, GO:0045944=IEA, GO:0005654=TAS} cell fate specification, embryo implantation, gene expression, hippo signaling cascade, muscle organ development, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, skeletal system development, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, trophectodermal cell fate commitment nucleoplasm, nucleus, transcription factor complex DNA binding, protein binding, sequence-specific DNA binding transcription factor activity Human Ensembl:ENSMUSP00000006311 TEC HPA UniProtKB {GO:0050853=PMID:10518561, GO:0005886=GO_REF:0000039, GO:0010543=PMID:9652744, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0007243=PMID:7934162, GO:0005829=Reactome:REACT_111221, GO:0035556=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0005543=GO_REF:0000002, GO:0004672=GO_REF:0000002, GO:0007229=PMID:9652744, GO:0006468=PMID:7934162, GO:0005856=PMID:9652744, GO:0004715=PMID:10518561} P42680 Tyrosine-protein kinase Tec protein 20080818 {GO:0050853=IDA, GO:0005886=IEA, GO:0010543=IDA, GO:0005524=IEA, GO:0046872=IEA, GO:0007243=TAS, GO:0005829=TAS, GO:0035556=IEA, GO:0005737=IDA, GO:0005543=IEA, GO:0004672=IEA, GO:0007229=IDA, GO:0006468=TAS, GO:0005856=IDA, GO:0004715=IDA} B cell receptor signaling pathway, integrin-mediated signaling pathway, intracellular protein kinase cascade, intracellular signal transduction, protein phosphorylation, regulation of platelet activation cytoplasm, cytoskeleton, cytosol, plasma membrane ATP binding, metal ion binding, non-membrane spanning protein tyrosine kinase activity, phospholipid binding, protein kinase activity Human TECPR1 IntAct UniProtKB {GO:0005515=PMID:20562859, GO:0000046=PMID:22342342, GO:0000421=PMID:21575909, GO:0006914=PMID:21575909, GO:0032266=PMID:22342342, GO:0031410=GO_REF:0000037, GO:0016021=GO_REF:0000002, GO:0005765=PMID:22342342} Q7Z6L1 Tectonin beta-propeller repeat-containing protein 1 protein 20130415 {GO:0005515=IPI, GO:0000046=IMP, GO:0000421=IDA, GO:0006914=IDA, GO:0032266=IDA, GO:0031410=IEA, GO:0016021=IEA, GO:0005765=IDA} autophagic vacuole fusion, autophagy autophagic vacuole membrane, cytoplasmic vesicle, integral to membrane, lysosomal membrane phosphatidylinositol-3-phosphate binding, protein binding Human UniProtKB:Q9NT62 TECPR2 IntAct UniProtKB {GO:0005515=PMID:20562859} O15040 Tectonin beta-propeller repeat-containing protein 2 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:Q9H0R8 TECR Reactome UniProtKB {GO:0006629=GO_REF:0000002, GO:0005737=GO_REF:0000002, GO:0019432=Reactome:REACT_1190, GO:0005789=Reactome:REACT_22330, GO:0030497=PMID:12482854, GO:0030176=PMID:12482854, GO:0044281=Reactome:REACT_111217, GO:0035338=Reactome:REACT_1319, GO:0016021=GO_REF:0000002, GO:0042761=PMID:12482854, GO:0016627=GO_REF:0000002, GO:0044255=Reactome:REACT_22279} Q9NZ01 Very-long-chain enoyl-CoA reductase protein 20130301 {GO:0006629=IEA, GO:0005737=IEA, GO:0019432=TAS, GO:0005789=TAS, GO:0030497=IDA, GO:0030176=IDA, GO:0044281=TAS, GO:0035338=TAS, GO:0016021=IEA, GO:0042761=IDA, GO:0016627=IEA, GO:0044255=TAS} cellular lipid metabolic process, fatty acid elongation, lipid metabolic process, long-chain fatty-acyl-CoA biosynthetic process, small molecule metabolic process, triglyceride biosynthetic process, very long-chain fatty acid biosynthetic process cytoplasm, endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane, integral to membrane oxidoreductase activity, acting on the CH-CH group of donors Human TEF PINC UniProtKB {GO:0043565=GO_REF:0000019, GO:0003690=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0006357=PMID:7835883, GO:0046982=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0048511=GO_REF:0000037, GO:0042803=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q10587 Thyrotroph embryonic factor protein 20030904 {GO:0043565=IEA, GO:0003690=IEA, GO:0003700=IEA, GO:0006357=TAS, GO:0046982=IEA, GO:0045944=IEA, GO:0005634=IEA, GO:0048511=IEA, GO:0042803=IEA, GO:0006351=IEA} positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, rhythmic process, transcription, DNA-dependent nucleus double-stranded DNA binding, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human TEK IntAct UniProtKB {GO:0005515=PMID:20708158, GO:2000251=PMID:12816861, GO:0050900=Reactome:REACT_12051, GO:0051259=PMID:19424712, GO:0007507=GO_REF:0000024, GO:0016337=GO_REF:0000019, GO:0009925=PMID:18425120, GO:0046777=PMID:11513602, GO:0043552=PMID:18425120, GO:0034446=PMID:18425119, GO:0070374=PMID:18425120, GO:0010740=PMID:19223473, GO:0009986=PMID:19689429, GO:0014068=PMID:18425120, GO:0018108=PMID:11513602, GO:0010595=PMID:15284220, GO:0060347=GO_REF:0000024, GO:0005887=PMID:19689429, GO:0045121=PMID:19615361, GO:0005925=GO_REF:0000039, GO:0051897=PMID:18425120, GO:0005886=Reactome:REACT_16914, GO:0005884=PMID:18425119, GO:0032878=PMID:18425119, GO:0007267=PMID:8980225, GO:0002040=PMID:14665640, GO:0051894=PMID:18425120, GO:0033138=GO_REF:0000019, GO:0005737=GO_REF:0000037, GO:0005911=PMID:18425120, GO:0004872=PMID:10766762, GO:0001725=PMID:18425119, GO:0043066=PMID:18366015, GO:0048014=PMID:15284220, GO:0060216=PMID:18366015, GO:0005576=GO_REF:0000039, GO:0001525=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0045766=PMID:15284220, GO:0007165=PMID:8382358, GO:2000351=PMID:18425120, GO:0004672=PMID:8382358, GO:0007160=GO_REF:0000019, GO:0001938=PMID:18425120, GO:0007596=Reactome:REACT_604, GO:0050728=PMID:18366015, GO:0001935=GO_REF:0000024, GO:0016525=PMID:18425120, GO:0001934=PMID:15284220, GO:0043114=PMID:18366015, GO:0004713=Reactome:REACT_13640, GO:2000352=GO_REF:0000024, GO:0004714=GO_REF:0000003, GO:0007169=PMID:15284220} Q02763 Angiopoietin-1 receptor protein 20130415 {GO:0005515=IPI, GO:2000251=IMP, GO:0050900=TAS, GO:0051259=IDA, GO:0007507=ISS, GO:0016337=IEA, GO:0009925=IDA, GO:0046777=IDA, GO:0043552=IMP, GO:0034446=IMP, GO:0070374=IMP, GO:0010740=IMP, GO:0009986=IDA, GO:0014068=IMP, GO:0018108=IDA, GO:0010595=IDA, GO:0060347=ISS, GO:0005887=IDA, GO:0045121=IDA, GO:0005925=IEA, GO:0051897=IMP, GO:0005886=TAS, GO:0005884=IDA, GO:0032878=IMP, GO:0007267=TAS, GO:0002040=IMP, GO:0051894=IMP, GO:0033138=IEA, GO:0005737=IEA, GO:0005911=IDA, GO:0004872=TAS, GO:0001725=IDA, GO:0043066=TAS, GO:0048014=IDA, GO:0060216=TAS, GO:0005576=IEA, GO:0001525=ISS, GO:0005524=IEA, GO:0045766=IDA, GO:0007165=TAS, GO:2000351=TAS, GO:0004672=TAS, GO:0007160=IEA, GO:0001938=TAS, GO:0007596=TAS, GO:0050728=TAS, GO:0001935=ISS, GO:0016525=IMP, GO:0001934=IDA, GO:0043114=TAS, GO:0004713=TAS, GO:2000352=ISS, GO:0004714=IEA, GO:0007169=IDA} Tie signaling pathway, angiogenesis, blood coagulation, cell-cell adhesion, cell-cell signaling, cell-matrix adhesion, definitive hemopoiesis, endothelial cell proliferation, heart development, heart trabecula formation, leukocyte migration, negative regulation of angiogenesis, negative regulation of apoptotic process, negative regulation of endothelial cell apoptotic process, negative regulation of inflammatory response, peptidyl-tyrosine phosphorylation, positive regulation of ERK1 and ERK2 cascade, positive regulation of actin cytoskeleton reorganization, positive regulation of angiogenesis, positive regulation of endothelial cell migration, positive regulation of endothelial cell proliferation, positive regulation of focal adhesion assembly, positive regulation of intracellular protein kinase cascade, positive regulation of peptidyl-serine phosphorylation, positive regulation of phosphatidylinositol 3-kinase activity, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of protein kinase B signaling cascade, positive regulation of protein phosphorylation, protein autophosphorylation, protein oligomerization, regulation of endothelial cell apoptotic process, regulation of establishment or maintenance of cell polarity, regulation of vascular permeability, signal transduction, sprouting angiogenesis, substrate adhesion-dependent cell spreading, transmembrane receptor protein tyrosine kinase signaling pathway actin filament, basal plasma membrane, cell surface, cell-cell junction, cytoplasm, extracellular region, focal adhesion, integral to plasma membrane, membrane raft, plasma membrane, stress fiber ATP binding, protein binding, protein kinase activity, protein tyrosine kinase activity, receptor activity, transmembrane receptor protein tyrosine kinase activity Human UniProtKB:O15123 TEKT4 UniProtKB UniProtKB {GO:0030030=GO_REF:0000037, GO:0005874=GO_REF:0000037, GO:0000226=GO_REF:0000002, GO:0035085=GO_REF:0000039} Q8WW24 Tektin-4 protein 20130413 {GO:0030030=IEA, GO:0005874=IEA, GO:0000226=IEA, GO:0035085=IEA} cell projection organization, microtubule cytoskeleton organization cilium axoneme, microtubule Human UniProtKB-SubCell:SL-0304 TELO2 HPA UniProtKB {GO:0005622=GO_REF:0000054, GO:0005515=PMID:20810650, GO:0032006=PMID:23263282, GO:0005737=GO_REF:0000052, GO:0000781=GO_REF:0000039, GO:0032947=GO_REF:0000019, GO:0031931=PMID:23263282, GO:0016020=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0031932=PMID:23263282, GO:0032403=PMID:20864032} Q9Y4R8 Telomere length regulation protein TEL2 homolog protein 20111111 {GO:0005622=IDA, GO:0005515=IPI, GO:0032006=IMP, GO:0005737=IDA, GO:0000781=IEA, GO:0032947=IEA, GO:0031931=IDA, GO:0016020=IEA, GO:0005634=IDA, GO:0031932=IDA, GO:0032403=IDA} regulation of TOR signaling cascade TORC1 complex, TORC2 complex, chromosome, telomeric region, cytoplasm, intracellular, membrane, nucleus protein binding, protein complex binding, protein complex scaffold Human TEN1 UniProtKB UniProtKB {GO:0005515=PMID:19854130, GO:0070188=GO_REF:0000024, GO:0005634=PMID:19854130, GO:0003677=GO_REF:0000037, GO:0000784=PMID:19854130} Q86WV5 CST complex subunit TEN1 protein 20100222 {GO:0005515=IPI, GO:0070188=ISS, GO:0005634=IDA, GO:0003677=IEA, GO:0000784=IDA} Stn1-Ten1 complex, nuclear chromosome, telomeric region, nucleus DNA binding, protein binding Human TENC1 UniProtKB UniProtKB {GO:0005515=PMID:17190795, GO:0019725=GO_REF:0000019, GO:0008285=PMID:16951145, GO:0005886=GO_REF:0000039, GO:0001822=GO_REF:0000019, GO:0014850=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0035556=GO_REF:0000002, GO:0048871=GO_REF:0000019, GO:0035264=GO_REF:0000019, GO:0032963=GO_REF:0000019, GO:0004721=GO_REF:0000037, GO:0005925=PMID:16951145} Q63HR2 Tensin-like C1 domain-containing phosphatase protein 20080509 {GO:0005515=IPI, GO:0019725=IEA, GO:0008285=IMP, GO:0005886=IEA, GO:0001822=IEA, GO:0014850=IEA, GO:0046872=IEA, GO:0035556=IEA, GO:0048871=IEA, GO:0035264=IEA, GO:0032963=IEA, GO:0004721=IEA, GO:0005925=IDA} cellular homeostasis, collagen metabolic process, intracellular signal transduction, kidney development, multicellular organism growth, multicellular organismal homeostasis, negative regulation of cell proliferation, response to muscle activity focal adhesion, plasma membrane metal ion binding, phosphoprotein phosphatase activity, protein binding Human UniProtKB:Q96QB1 TEP1 MGI UniProtKB {GO:0005737=PMID:7876352, GO:0005697=PMID:12135483, GO:0000781=GO_REF:0000039, GO:0003720=PMID:12135483, GO:0030529=PMID:15701761, GO:0003723=GO_REF:0000024, GO:0000722=PMID:10810353, GO:0005524=GO_REF:0000037, GO:0016363=PMID:7876352} Q99973 Telomerase protein component 1 protein 20110609 {GO:0005737=IDA, GO:0005697=IDA, GO:0000781=IEA, GO:0003720=IDA, GO:0030529=TAS, GO:0003723=ISS, GO:0000722=IDA, GO:0005524=IEA, GO:0016363=IDA} telomere maintenance via recombination chromosome, telomeric region, cytoplasm, nuclear matrix, ribonucleoprotein complex, telomerase holoenzyme complex ATP binding, RNA binding, telomerase activity Human TERF1 BHF-UCL UniProtKB {GO:0051974=PMID:11971978, GO:0005515=PMID:22153077, GO:0000781=PMID:15380063, GO:0010521=PMID:11971978, GO:0008301=PMID:9130722, GO:0010834=PMID:11971978, GO:0042493=GO_REF:0000019, GO:0042162=GO_REF:0000002, GO:0005819=GO_REF:0000039, GO:0005634=PMID:11313893, GO:0003677=PMID:7502076, GO:0042803=PMID:9130722, GO:0005737=GO_REF:0000037, GO:0032211=PMID:11971978, GO:0003691=PMID:15608617, GO:0007067=GO_REF:0000037, GO:0000723=Reactome:REACT_7970, GO:0003682=GO_REF:0000002, GO:0032214=PMID:15007108, GO:0005654=Reactome:REACT_8031, GO:0008156=PMID:11327863, GO:0007004=PMID:7502076, GO:0000783=PMID:7502076, GO:0051301=GO_REF:0000037} P54274 Telomeric repeat-binding factor 1 protein 20081208 {GO:0051974=IGI, GO:0005515=IPI, GO:0000781=IDA, GO:0010521=IGI, GO:0008301=IDA, GO:0010834=IMP, GO:0042493=IEA, GO:0042162=IEA, GO:0005819=IEA, GO:0005634=IDA, GO:0003677=NAS, GO:0042803=IPI, GO:0005737=IEA, GO:0032211=IGI, GO:0003691=IDA, GO:0007067=IEA, GO:0000723=TAS, GO:0003682=IEA, GO:0032214=NAS, GO:0005654=TAS, GO:0008156=IDA, GO:0007004=NAS, GO:0000783=ISS, GO:0051301=IEA} cell division, mitosis, negative regulation of DNA replication, negative regulation of telomerase activity, negative regulation of telomere maintenance via semi-conservative replication, negative regulation of telomere maintenance via telomerase, response to drug, telomere maintenance, telomere maintenance via telomerase, telomere maintenance via telomere shortening chromosome, telomeric region, cytoplasm, nuclear telomere cap complex, nucleoplasm, nucleus, spindle DNA binding, DNA binding, bending, chromatin binding, double-stranded telomeric DNA binding, protein binding, protein homodimerization activity, telomerase inhibitor activity, telomeric DNA binding Human UniProtKB:O14746 TERF2 HPA UniProtKB {GO:0005515=PMID:10984620, GO:0030870=PMID:10888888, GO:0010834=PMID:11971978, GO:0005634=GO_REF:0000052, GO:0042803=PMID:9326950, GO:0005737=GO_REF:0000052, GO:0003691=PMID:9326950, GO:0000723=Reactome:REACT_7970, GO:0032214=PMID:15007108, GO:0031627=PMID:10338214, GO:0070198=PMID:17499040, GO:0000783=PMID:15181449, GO:0000781=PMID:12768206, GO:0016233=PMID:12768206, GO:0005794=GO_REF:0000052, GO:0042162=PMID:20655466, GO:0005730=GO_REF:0000052, GO:0008022=PMID:12181313, GO:0001701=GO_REF:0000019, GO:0031848=PMID:17499040, GO:0001309=PMID:17395247, GO:0007049=GO_REF:0000037, GO:0003682=GO_REF:0000002, GO:0032205=PMID:17055345, GO:0005654=Reactome:REACT_8031, GO:0032206=GO_REF:0000019, GO:0001673=GO_REF:0000019, GO:0007004=PMID:15657433, GO:0090398=PMID:17395247} Q15554 Telomeric repeat-binding factor 2 protein 20080205 {GO:0005515=IPI, GO:0030870=IDA, GO:0010834=IMP, GO:0005634=IDA, GO:0042803=IPI, GO:0005737=IDA, GO:0003691=ISS, GO:0000723=TAS, GO:0032214=NAS, GO:0031627=IDA, GO:0070198=IMP, GO:0000783=IDA, GO:0000781=IDA, GO:0016233=IMP, GO:0005794=IDA, GO:0042162=IDA, GO:0005730=IDA, GO:0008022=IPI, GO:0001701=IEA, GO:0031848=IMP, GO:0001309=NAS, GO:0007049=IEA, GO:0003682=IEA, GO:0032205=IDA, GO:0005654=TAS, GO:0032206=IEA, GO:0001673=IEA, GO:0007004=IC, GO:0090398=NAS} age-dependent telomere shortening, cell cycle, cellular senescence, in utero embryonic development, negative regulation of telomere maintenance, negative regulation of telomere maintenance via semi-conservative replication, positive regulation of telomere maintenance, protection from non-homologous end joining at telomere, protein localization to chromosome, telomeric region, telomere capping, telomere maintenance, telomere maintenance via telomerase, telomere maintenance via telomere shortening, telomeric loop formation Golgi apparatus, Mre11 complex, chromosome, telomeric region, cytoplasm, male germ cell nucleus, nuclear telomere cap complex, nucleolus, nucleoplasm, nucleus chromatin binding, double-stranded telomeric DNA binding, protein C-terminus binding, protein binding, protein homodimerization activity, telomeric DNA binding Human TERF2IP HPA UniProtKB {GO:0005515=PMID:19651898, GO:0006355=GO_REF:0000024, GO:0000781=PMID:12768206, GO:0030870=PMID:15100233, GO:0048239=GO_REF:0000024, GO:0042162=PMID:10850490, GO:0005634=GO_REF:0000052, GO:0010833=GO_REF:0000024, GO:0000228=PMID:10850490, GO:0003677=GO_REF:0000002, GO:0010569=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0031848=PMID:17499040, GO:0005737=GO_REF:0000052, GO:0051092=GO_REF:0000024, GO:0000723=PMID:14565979, GO:0005654=Reactome:REACT_8031, GO:0032205=PMID:15100233, GO:0007004=PMID:10850490, GO:0043123=GO_REF:0000024, GO:0070198=PMID:17499040, GO:0000784=PMID:14565979, GO:0000783=PMID:15181449} Q9NYB0 Telomeric repeat-binding factor 2-interacting protein 1 protein 20080205 {GO:0005515=IPI, GO:0006355=ISS, GO:0000781=IDA, GO:0030870=IDA, GO:0048239=ISS, GO:0042162=TAS, GO:0005634=IDA, GO:0010833=ISS, GO:0000228=TAS, GO:0003677=IEA, GO:0010569=ISS, GO:0006351=IEA, GO:0031848=IMP, GO:0005737=IDA, GO:0051092=ISS, GO:0000723=IDA, GO:0005654=TAS, GO:0032205=IMP, GO:0007004=TAS, GO:0043123=ISS, GO:0070198=IMP, GO:0000784=IDA, GO:0000783=IDA} negative regulation of DNA recombination at telomere, negative regulation of telomere maintenance, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB transcription factor activity, protection from non-homologous end joining at telomere, protein localization to chromosome, telomeric region, regulation of double-strand break repair via homologous recombination, regulation of transcription, DNA-dependent, telomere maintenance, telomere maintenance via telomerase, telomere maintenance via telomere lengthening, transcription, DNA-dependent Mre11 complex, chromosome, telomeric region, cytoplasm, nuclear chromosome, nuclear chromosome, telomeric region, nuclear telomere cap complex, nucleoplasm, nucleus DNA binding, protein binding, telomeric DNA binding Human TERT UniProtKB UniProtKB {GO:0005515=PMID:17237767, GO:0043066=PMID:10449030, GO:0005697=PMID:12135483, GO:0000781=PMID:12135483, GO:0003721=PMID:15632080, GO:0003720=PMID:16043710, GO:0003723=GO_REF:0000002, GO:0042162=PMID:9288757, GO:0005730=GO_REF:0000039, GO:0042803=PMID:11432839, GO:0046872=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0000723=Reactome:REACT_7970, GO:0016605=PMID:19567472, GO:0003964=GO_REF:0000038, GO:0022616=PMID:16043710, GO:0032203=PMID:16043710, GO:0005654=Reactome:REACT_8019, GO:0090399=PMID:9454332, GO:0007004=PMID:9454332, GO:0006278=GO_REF:0000002, GO:0070034=PMID:11432839, GO:0000783=PMID:15632080} Q8NG38 Telomerase reverse transcriptase, isoform CRA_c protein 20130413 {GO:0005515=IPI, GO:0043066=IMP, GO:0005697=IDA, GO:0000781=IC, GO:0003721=IDA, GO:0003720=IDA, GO:0003723=IEA, GO:0042162=TAS, GO:0005730=IEA, GO:0042803=IDA, GO:0046872=IEA, GO:0005737=IEA, GO:0000723=TAS, GO:0016605=IDA, GO:0003964=IEA, GO:0022616=IDA, GO:0032203=IDA, GO:0005654=TAS, GO:0090399=IMP, GO:0007004=IMP, GO:0006278=IEA, GO:0070034=IDA, GO:0000783=IC} DNA strand elongation, RNA-dependent DNA replication, negative regulation of apoptotic process, replicative senescence, telomere formation via telomerase, telomere maintenance, telomere maintenance via telomerase PML body, chromosome, telomeric region, cytoplasm, nuclear telomere cap complex, nucleolus, nucleoplasm, telomerase holoenzyme complex RNA binding, RNA-directed DNA polymerase activity, metal ion binding, protein binding, protein homodimerization activity, telomerase activity, telomeric DNA binding, telomeric RNA binding, telomeric template RNA reverse transcriptase activity Human UniProtKB-KW:KW-0695 TES HPA UniProtKB {GO:0043234=PMID:21278383, GO:0005737=GO_REF:0000052, GO:0030054=GO_REF:0000052, GO:0008285=PMID:11420696, GO:0005886=GO_REF:0000052, GO:0008270=PMID:21278383, GO:0005925=GO_REF:0000039} Q9UGI8 Testin protein 20090616 {GO:0043234=IDA, GO:0005737=IDA, GO:0030054=IDA, GO:0008285=IMP, GO:0005886=IDA, GO:0008270=IDA, GO:0005925=IEA} negative regulation of cell proliferation cell junction, cytoplasm, focal adhesion, plasma membrane, protein complex zinc ion binding Human TESC IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0033628=PMID:17717601, GO:0008285=PMID:17717601, GO:0032417=PMID:18321853, GO:0005886=PMID:21553168, GO:0071300=PMID:20060826, GO:0072661=PMID:18321853, GO:0005634=PMID:19345287, GO:0042803=GO_REF:0000024, GO:0051604=PMID:18321853, GO:0045654=PMID:17717601, GO:0005737=PMID:19345287, GO:0030854=PMID:20060826, GO:0000287=GO_REF:0000024, GO:0005509=PMID:21553168, GO:0050821=PMID:18321853, GO:0032587=GO_REF:0000039, GO:0019212=GO_REF:0000024, GO:0001726=GO_REF:0000024, GO:0030027=PMID:11696366, GO:0010628=PMID:17717601, GO:0030219=GO_REF:0000019, GO:0004860=GO_REF:0000037, GO:0045893=PMID:17717601, GO:0008584=GO_REF:0000019} Q96BS2 Calcineurin B homologous protein 3 protein 20130415 {GO:0005515=IPI, GO:0033628=IMP, GO:0008285=IMP, GO:0032417=IDA, GO:0005886=IDA, GO:0071300=IDA, GO:0072661=IDA, GO:0005634=IDA, GO:0042803=ISS, GO:0051604=IDA, GO:0045654=IMP, GO:0005737=IDA, GO:0030854=IDA, GO:0000287=ISS, GO:0005509=IDA, GO:0050821=IDA, GO:0032587=IEA, GO:0019212=ISS, GO:0001726=ISS, GO:0030027=IDA, GO:0010628=IMP, GO:0030219=IEA, GO:0004860=IEA, GO:0045893=IMP, GO:0008584=IEA} cellular response to retinoic acid, male gonad development, megakaryocyte differentiation, negative regulation of cell proliferation, positive regulation of gene expression, positive regulation of granulocyte differentiation, positive regulation of megakaryocyte differentiation, positive regulation of sodium:hydrogen antiporter activity, positive regulation of transcription, DNA-dependent, protein maturation, protein stabilization, protein targeting to plasma membrane, regulation of cell adhesion mediated by integrin cytoplasm, lamellipodium, nucleus, plasma membrane, ruffle, ruffle membrane calcium ion binding, magnesium ion binding, phosphatase inhibitor activity, protein binding, protein homodimerization activity, protein kinase inhibitor activity Human UniProtKB:Q9NP66 TESK1 IntAct UniProtKB {GO:0005515=PMID:12027893, GO:0004674=GO_REF:0000019, GO:0034329=Reactome:REACT_20676, GO:0004712=GO_REF:0000003, GO:0007283=GO_REF:0000019, GO:0004713=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_20609} Q15569 Dual specificity testis-specific protein kinase 1 protein 20130415 {GO:0005515=IPI, GO:0004674=IEA, GO:0034329=TAS, GO:0004712=IEA, GO:0007283=IEA, GO:0004713=IEA, GO:0005524=IEA, GO:0046872=IEA, GO:0005829=TAS} cell junction assembly, spermatogenesis cytosol ATP binding, metal ion binding, protein binding, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity, protein tyrosine kinase activity Human UniProtKB:Q9C004 TESK2 HPA UniProtKB {GO:0005515=PMID:22939624, GO:0030036=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0007283=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0005737=GO_REF:0000019, GO:0004672=PMID:10512679, GO:0004674=GO_REF:0000024, GO:0048041=GO_REF:0000024, GO:0004712=GO_REF:0000003, GO:0006468=GO_REF:0000024, GO:0004713=GO_REF:0000037} Q96S53 Dual specificity testis-specific protein kinase 2 protein 20101115 {GO:0005515=IPI, GO:0030036=ISS, GO:0005730=IDA, GO:0005634=IDA, GO:0007283=ISS, GO:0005524=IEA, GO:0046872=IEA, GO:0005737=IEA, GO:0004672=TAS, GO:0004674=ISS, GO:0048041=ISS, GO:0004712=IEA, GO:0006468=ISS, GO:0004713=IEA} actin cytoskeleton organization, focal adhesion assembly, protein phosphorylation, spermatogenesis cytoplasm, nucleolus, nucleus ATP binding, metal ion binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity, protein tyrosine kinase activity NOT Human TET1 UniProtKB UniProtKB {GO:0005506=PMID:19372391, GO:0001826=GO_REF:0000024, GO:0005634=PMID:19372391, GO:0090310=PMID:21496894, GO:0006351=GO_REF:0000037, GO:0006493=GO_REF:0000024, GO:0045944=GO_REF:0000024, GO:0019827=GO_REF:0000024, GO:0044030=GO_REF:0000019, GO:0043566=PMID:19372391, GO:0080111=PMID:21496894, GO:0008270=GO_REF:0000002, GO:0016702=GO_REF:0000037, GO:0070579=PMID:21496894, GO:0016568=GO_REF:0000037} Q8NFU7 Methylcytosine dioxygenase TET1 protein 20130315 {GO:0005506=IDA, GO:0001826=ISS, GO:0005634=IC, GO:0090310=IMP, GO:0006351=IEA, GO:0006493=ISS, GO:0045944=ISS, GO:0019827=ISS, GO:0044030=IEA, GO:0043566=IDA, GO:0080111=IMP, GO:0008270=IEA, GO:0016702=IEA, GO:0070579=IMP, GO:0016568=IEA} DNA demethylation, chromatin modification, inner cell mass cell differentiation, negative regulation of methylation-dependent chromatin silencing, positive regulation of transcription from RNA polymerase II promoter, protein O-linked glycosylation, regulation of DNA methylation, stem cell maintenance, transcription, DNA-dependent nucleus iron ion binding, methylcytosine dioxygenase activity, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, structure-specific DNA binding, zinc ion binding Human UniProtKB:Q3URK3 TET2 UniProtKB UniProtKB {GO:0005515=PMID:23353889, GO:0007049=GO_REF:0000037, GO:0006493=PMID:23353889, GO:0001822=GO_REF:0000019, GO:0045944=PMID:23353889, GO:0080182=PMID:23353889, GO:0080111=GO_REF:0000019, GO:0030099=PMID:21057493, GO:0016702=GO_REF:0000037, GO:0070579=PMID:23222540, GO:0009791=GO_REF:0000019, GO:0046872=GO_REF:0000037} Q6N021 Methylcytosine dioxygenase TET2 protein 20130315 {GO:0005515=IPI, GO:0007049=IEA, GO:0006493=IMP, GO:0001822=IEA, GO:0045944=IMP, GO:0080182=IMP, GO:0080111=IEA, GO:0030099=IMP, GO:0016702=IEA, GO:0070579=IMP, GO:0009791=IEA, GO:0046872=IEA} DNA demethylation, cell cycle, histone H3-K4 trimethylation, kidney development, myeloid cell differentiation, positive regulation of transcription from RNA polymerase II promoter, post-embryonic development, protein O-linked glycosylation metal ion binding, methylcytosine dioxygenase activity, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, protein binding Human UniProtKB:O15294 TET3 UniProtKB UniProtKB {GO:0005515=PMID:23353889, GO:0005737=GO_REF:0000024, GO:0001939=GO_REF:0000019, GO:0006493=PMID:23353889, GO:0045944=PMID:23353889, GO:0080182=PMID:23353889, GO:0080111=GO_REF:0000024, GO:0044727=GO_REF:0000024, GO:0001940=GO_REF:0000024, GO:0070579=GO_REF:0000024, GO:0016702=GO_REF:0000037, GO:0046872=GO_REF:0000037} O43151 Methylcytosine dioxygenase TET3 protein 20130315 {GO:0005515=IPI, GO:0005737=ISS, GO:0001939=IEA, GO:0006493=IMP, GO:0045944=IMP, GO:0080182=IMP, GO:0080111=ISS, GO:0044727=ISS, GO:0001940=ISS, GO:0070579=ISS, GO:0016702=IEA, GO:0046872=IEA} DNA demethylation, DNA demethylation of male pronucleus, histone H3-K4 trimethylation, positive regulation of transcription from RNA polymerase II promoter, protein O-linked glycosylation cytoplasm, female pronucleus, male pronucleus metal ion binding, methylcytosine dioxygenase activity, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, protein binding Human UniProtKB:O15294 TEX10 UniProtKB UniProtKB {GO:0031965=GO_REF:0000039, GO:0005737=GO_REF:0000039, GO:0071339=PMID:15960975, GO:0005730=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q9NXF1 Testis-expressed sequence 10 protein protein 20091215 {GO:0031965=IEA, GO:0005737=IEA, GO:0071339=IDA, GO:0005730=IEA, GO:0016021=IEA} MLL1 complex, cytoplasm, integral to membrane, nuclear membrane, nucleolus Human TEX101 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0031225=GO_REF:0000037} Q9BY14 Testis-expressed sequence 101 protein protein 20130413 {GO:0005886=IEA, GO:0031225=IEA} anchored to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 TEX11 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0009566=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0000795=GO_REF:0000024, GO:0051026=GO_REF:0000019, GO:0000712=GO_REF:0000019, GO:0000801=GO_REF:0000019, GO:0006311=GO_REF:0000024, GO:0007060=GO_REF:0000019, GO:0007130=GO_REF:0000019, GO:0008584=GO_REF:0000019, GO:0007131=GO_REF:0000024} Q8IYF3 Testis-expressed sequence 11 protein protein 20130415 {GO:0005515=IPI, GO:0009566=IEA, GO:0043066=IEA, GO:0000795=ISS, GO:0051026=IEA, GO:0000712=IEA, GO:0000801=IEA, GO:0006311=ISS, GO:0007060=IEA, GO:0007130=IEA, GO:0008584=IEA, GO:0007131=ISS} chiasma assembly, fertilization, male gonad development, male meiosis chromosome segregation, meiotic gene conversion, negative regulation of apoptotic process, reciprocal meiotic recombination, resolution of meiotic recombination intermediates, synaptonemal complex assembly central element, synaptonemal complex protein binding Human UniProtKB:Q96GY3 TEX14 UniProtKB UniProtKB {GO:0032091=GO_REF:0000019, GO:0043063=GO_REF:0000024, GO:0007094=GO_REF:0000024, GO:0032466=GO_REF:0000019, GO:0019901=PMID:22405274, GO:0005623=GO_REF:0000024, GO:0030496=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0045171=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0051306=GO_REF:0000024, GO:0004672=GO_REF:0000002, GO:0000777=GO_REF:0000039, GO:0000776=GO_REF:0000024, GO:0008608=GO_REF:0000024, GO:0007140=GO_REF:0000024, GO:0051301=GO_REF:0000037} Q8IWB6 Inactive serine/threonine-protein kinase TEX14 protein 20120329 {GO:0032091=IEA, GO:0043063=ISS, GO:0007094=ISS, GO:0032466=IEA, GO:0019901=IPI, GO:0005623=ISS, GO:0030496=ISS, GO:0005524=IEA, GO:0045171=ISS, GO:0005737=IEA, GO:0051306=ISS, GO:0004672=IEA, GO:0000777=IEA, GO:0000776=ISS, GO:0008608=ISS, GO:0007140=ISS, GO:0051301=IEA} attachment of spindle microtubules to kinetochore, cell division, intercellular bridge organization, male meiosis, mitotic sister chromatid separation, mitotic spindle assembly checkpoint, negative regulation of cytokinesis, negative regulation of protein binding cell, condensed chromosome kinetochore, cytoplasm, intercellular bridge, kinetochore, midbody ATP binding, protein kinase activity, protein kinase binding Human UniProtKB:Q7M6U3 TEX2 UniProtKB UniProtKB {GO:0006665=PMID:16449791, GO:0003674=GO_REF:0000015, GO:0007165=PMID:16449791, GO:0005543=GO_REF:0000002, GO:0016020=GO_REF:0000038, GO:0016021=PMID:16449791} Q8IWB9 Testis-expressed sequence 2 protein protein 20080604 {GO:0006665=NAS, GO:0003674=ND, GO:0007165=NAS, GO:0005543=IEA, GO:0016020=IEA, GO:0016021=NAS} signal transduction, sphingolipid metabolic process integral to membrane, membrane molecular_function, phospholipid binding Human TEX264 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q9Y6I9 Testis-expressed sequence 264 protein protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 TEX28 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0016021=GO_REF:0000029} O15482 Testis-specific protein TEX28 protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0016021=NAS} biological_process integral to membrane molecular_function Human TEX9 null null {} null null null null {} null null null TF HPA UniProtKB {GO:0005515=PMID:15880641, GO:0048471=PMID:15880641, GO:0005770=PMID:15880641, GO:0045178=PMID:15880641, GO:0030168=Reactome:REACT_798, GO:0030139=PMID:15292400, GO:0005576=Reactome:REACT_25389, GO:0055085=Reactome:REACT_15518, GO:0008199=GO_REF:0000002, GO:0005739=GO_REF:0000052, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0005905=PMID:12857860, GO:0016324=PMID:11208127, GO:0009925=PMID:15880641, GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0006826=GO_REF:0000002, GO:0016023=PMID:12857860, GO:0055037=PMID:15880641, GO:0034774=Reactome:REACT_21324, GO:0010008=Reactome:REACT_25389, GO:0031625=GO_REF:0000019, GO:0005769=PMID:15880641} P02787 Serotransferrin protein 20080205 {GO:0005515=IPI, GO:0048471=IDA, GO:0005770=IDA, GO:0045178=IDA, GO:0030168=TAS, GO:0030139=IDA, GO:0005576=TAS, GO:0055085=TAS, GO:0008199=IEA, GO:0005739=IDA, GO:0006879=TAS, GO:0033572=TAS, GO:0005905=IDA, GO:0016324=IDA, GO:0009925=IDA, GO:0007596=TAS, GO:0002576=TAS, GO:0006826=IEA, GO:0016023=IDA, GO:0055037=IDA, GO:0034774=TAS, GO:0010008=TAS, GO:0031625=IEA, GO:0005769=IDA} blood coagulation, cellular iron ion homeostasis, iron ion transport, platelet activation, platelet degranulation, transferrin transport, transmembrane transport apical plasma membrane, basal part of cell, basal plasma membrane, coated pit, cytoplasmic membrane-bounded vesicle, early endosome, endocytic vesicle, endosome membrane, extracellular region, late endosome, mitochondrion, perinuclear region of cytoplasm, recycling endosome, secretory granule lumen ferric iron binding, protein binding, ubiquitin protein ligase binding Human TFAM HPA UniProtKB {GO:0042645=PMID:18063578, GO:0005515=PMID:12897151, GO:0010467=Reactome:REACT_71, GO:0003700=PMID:22037171, GO:0008301=PMID:22037171, GO:0006356=PMID:8333869, GO:0006391=Reactome:REACT_367, GO:0006390=Reactome:REACT_1484, GO:0005739=GO_REF:0000052, GO:0006261=PMID:8333869, GO:0031072=GO_REF:0000019, GO:0003682=PMID:18063578, GO:0005759=Reactome:REACT_875, GO:0033108=GO_REF:0000019, GO:0045893=PMID:20410300, GO:0070363=PMID:19304746} Q00059 Transcription factor A, mitochondrial protein 20110516 {GO:0042645=IDA, GO:0005515=IPI, GO:0010467=TAS, GO:0003700=IMP, GO:0008301=IDA, GO:0006356=TAS, GO:0006391=TAS, GO:0006390=TAS, GO:0005739=IDA, GO:0006261=TAS, GO:0031072=IEA, GO:0003682=IDA, GO:0005759=TAS, GO:0033108=IEA, GO:0045893=IDA, GO:0070363=IDA} DNA-dependent DNA replication, gene expression, mitochondrial respiratory chain complex assembly, positive regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase I promoter, transcription from mitochondrial promoter, transcription initiation from mitochondrial promoter mitochondrial matrix, mitochondrial nucleoid, mitochondrion DNA binding, bending, chromatin binding, heat shock protein binding, mitochondrial light strand promoter sense binding, protein binding, sequence-specific DNA binding transcription factor activity Human TFAP2A HPA UniProtKB {GO:0000987=PMID:7559606, GO:0005515=PMID:12586840, GO:0003700=GO_REF:0000002, GO:0006366=PMID:7555706, GO:0044212=PMID:12586840, GO:0000981=PMID:7555706, GO:0070172=PMID:19578371, GO:0007605=PMID:21204207, GO:0000982=PMID:21084835, GO:0021559=GO_REF:0000024, GO:0048701=GO_REF:0000024, GO:0042803=PMID:7559606, GO:0043231=GO_REF:0000052, GO:0009880=GO_REF:0000019, GO:0043525=PMID:20607706, GO:0010944=PMID:11278550, GO:0014032=GO_REF:0000019, GO:0046983=PMID:12072434, GO:0021623=GO_REF:0000024, GO:0005813=GO_REF:0000052, GO:0001105=GO_REF:0000019, GO:0030501=PMID:19578371, GO:0042472=PMID:21204207, GO:0030335=GO_REF:0000019, GO:0005794=GO_REF:0000052, GO:0060235=GO_REF:0000019, GO:0001106=GO_REF:0000019, GO:0003404=GO_REF:0000024, GO:0003713=PMID:7555706, GO:0042059=GO_REF:0000019, GO:0010842=PMID:20607706, GO:0000122=PMID:8321221, GO:0000978=PMID:9520389, GO:0000979=PMID:7555706, GO:0003409=GO_REF:0000024, GO:0048485=GO_REF:0000019, GO:0060349=GO_REF:0000024, GO:0043588=GO_REF:0000019, GO:0000980=GO_REF:0000019, GO:0045595=PMID:20607706, GO:2000378=PMID:20066163, GO:0021884=GO_REF:0000019, GO:0045893=GO_REF:0000024, GO:0071281=PMID:20808827, GO:0008285=PMID:20607706, GO:0005634=GO_REF:0000052, GO:0003334=GO_REF:0000019, GO:0072210=GO_REF:0000019, GO:0048730=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0045944=PMID:7555706, GO:0061029=GO_REF:0000024, GO:0060021=PMID:21204207, GO:0071711=GO_REF:0000019, GO:0043066=PMID:20066163, GO:0010172=GO_REF:0000019, GO:0001822=PMID:21204207, GO:0005730=GO_REF:0000052, GO:0003151=GO_REF:0000019, GO:0021506=GO_REF:0000019, GO:0043565=PMID:12586840, GO:0010628=GO_REF:0000024, GO:0061303=GO_REF:0000019, GO:0001077=PMID:20808827, GO:0060325=GO_REF:0000019, GO:0003682=GO_REF:0000024, GO:0045664=GO_REF:0000019, GO:0035115=GO_REF:0000024} Q96SH1 Transcription factor AP-2 alpha (Activating enhancer binding protein 2 alpha), isoform CRA_c protein 20101115 {GO:0000987=IDA, GO:0005515=IPI, GO:0003700=IEA, GO:0006366=IDA, GO:0044212=IDA, GO:0000981=IDA, GO:0070172=IDA, GO:0007605=IMP, GO:0000982=IDA, GO:0021559=ISS, GO:0048701=ISS, GO:0042803=TAS, GO:0043231=IDA, GO:0009880=IEA, GO:0043525=IDA, GO:0010944=IMP, GO:0014032=IEA, GO:0046983=IDA, GO:0021623=ISS, GO:0005813=IDA, GO:0001105=IEA, GO:0030501=IDA, GO:0042472=IMP, GO:0030335=IEA, GO:0005794=IDA, GO:0060235=IEA, GO:0001106=IEA, GO:0003404=ISS, GO:0003713=IDA, GO:0042059=IEA, GO:0010842=IEP, GO:0000122=IDA, GO:0000978=IDA, GO:0000979=IDA, GO:0003409=ISS, GO:0048485=IEA, GO:0060349=ISS, GO:0043588=IEA, GO:0000980=IEA, GO:0045595=IDA, GO:2000378=IDA, GO:0021884=IEA, GO:0045893=ISS, GO:0071281=IDA, GO:0008285=IDA, GO:0005634=IDA, GO:0003334=IEA, GO:0072210=IEA, GO:0048730=IEA, GO:0005737=IDA, GO:0045944=IDA, GO:0061029=ISS, GO:0060021=IMP, GO:0071711=IEA, GO:0043066=IDA, GO:0010172=IEA, GO:0001822=IMP, GO:0005730=IDA, GO:0003151=IEA, GO:0021506=IEA, GO:0043565=IDA, GO:0010628=ISS, GO:0061303=IEA, GO:0001077=IDA, GO:0060325=IEA, GO:0003682=ISS, GO:0045664=IEA, GO:0035115=ISS} anterior neuropore closure, basement membrane organization, bone morphogenesis, cellular response to iron ion, cornea development in camera-type eye, embryonic body morphogenesis, embryonic cranial skeleton morphogenesis, embryonic forelimb morphogenesis, embryonic pattern specification, epidermis morphogenesis, eyelid development in camera-type eye, face morphogenesis, forebrain neuron development, inner ear morphogenesis, keratinocyte development, kidney development, lens induction in camera-type eye, metanephric nephron development, negative regulation of apoptotic process, negative regulation of cell proliferation, negative regulation of epidermal growth factor receptor signaling pathway, negative regulation of reactive oxygen species metabolic process, negative regulation of transcription by competitive promoter binding, negative regulation of transcription from RNA polymerase II promoter, neural crest cell development, oculomotor nerve formation, optic cup structural organization, optic vesicle morphogenesis, outflow tract morphogenesis, palate development, positive regulation of bone mineralization, positive regulation of cell migration, positive regulation of gene expression, positive regulation of neuron apoptotic process, positive regulation of tooth mineralization, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of cell differentiation, regulation of neuron differentiation, retina layer formation, sensory perception of sound, skin development, sympathetic nervous system development, transcription from RNA polymerase II promoter, trigeminal nerve development Golgi apparatus, centrosome, cytoplasm, intracellular membrane-bounded organelle, nucleolus, nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II core promoter sequence-specific DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding, RNA polymerase II transcription coactivator activity, RNA polymerase II transcription corepressor activity, chromatin binding, core promoter proximal region sequence-specific DNA binding, protein binding, protein dimerization activity, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, transcription regulatory region DNA binding Human TFAP2B HGNC UniProtKB {GO:0005515=PMID:19115315, GO:0035137=GO_REF:0000024, GO:0035136=GO_REF:0000024, GO:0003700=PMID:12169688, GO:0000983=GO_REF:0000024, GO:0000981=PMID:7555706, GO:0042803=PMID:11505339, GO:0043525=PMID:20607706, GO:0097277=GO_REF:0000024, GO:0097276=GO_REF:0000024, GO:0097275=GO_REF:0000024, GO:0046983=PMID:12072434, GO:0045444=PMID:16373396, GO:0043027=GO_REF:0000024, GO:0001105=GO_REF:0000024, GO:0046982=PMID:11505339, GO:0001106=GO_REF:0000024, GO:0003714=PMID:7559606, GO:0072044=GO_REF:0000024, GO:0003713=PMID:7555706, GO:0055062=GO_REF:0000024, GO:0010842=PMID:20607706, GO:0000979=PMID:7555706, GO:0048485=GO_REF:0000024, GO:0045595=PMID:20607706, GO:0043588=GO_REF:0000019, GO:0035810=GO_REF:0000024, GO:0045893=PMID:11505339, GO:0001158=PMID:16373396, GO:0008284=PMID:17525748, GO:0008285=PMID:20607706, GO:0055075=GO_REF:0000024, GO:0005634=PMID:12169688, GO:0072017=GO_REF:0000024, GO:0055078=GO_REF:0000024, GO:0072210=GO_REF:0000019, GO:0055074=GO_REF:0000024, GO:0010960=GO_REF:0000024, GO:0045944=PMID:12169688, GO:0006006=PMID:19325541, GO:0097070=GO_REF:0000024, GO:0043154=GO_REF:0000024, GO:0030510=GO_REF:0000024, GO:0006355=PMID:12169688, GO:0043066=PMID:17525748, GO:0001822=GO_REF:0000024, GO:0035909=GO_REF:0000024, GO:0042593=GO_REF:0000024, GO:0003677=PMID:12072434, GO:0003091=GO_REF:0000024, GO:0043565=PMID:12169688, GO:0001077=GO_REF:0000019, GO:0050796=PMID:19325541} Q92481 Transcription factor AP-2-beta protein 20061201 {GO:0005515=IPI, GO:0035137=ISS, GO:0035136=ISS, GO:0003700=IDA, GO:0000983=ISS, GO:0000981=IDA, GO:0042803=IPI, GO:0043525=IDA, GO:0097277=ISS, GO:0097276=ISS, GO:0097275=ISS, GO:0046983=IDA, GO:0045444=IEP, GO:0043027=ISS, GO:0001105=ISS, GO:0046982=IPI, GO:0001106=ISS, GO:0003714=IDA, GO:0072044=ISS, GO:0003713=IDA, GO:0055062=ISS, GO:0010842=IEP, GO:0000979=IDA, GO:0048485=ISS, GO:0045595=IDA, GO:0043588=IEA, GO:0035810=ISS, GO:0045893=IDA, GO:0001158=IDA, GO:0008284=IDA, GO:0008285=IDA, GO:0055075=ISS, GO:0005634=IC, GO:0072017=ISS, GO:0055078=ISS, GO:0072210=IEA, GO:0055074=ISS, GO:0010960=ISS, GO:0045944=IDA, GO:0006006=IMP, GO:0097070=ISS, GO:0043154=ISS, GO:0030510=ISS, GO:0006355=IDA, GO:0043066=IDA, GO:0001822=ISS, GO:0035909=ISS, GO:0042593=ISS, GO:0003677=TAS, GO:0003091=ISS, GO:0043565=IDA, GO:0001077=IEA, GO:0050796=IMP} aorta morphogenesis, calcium ion homeostasis, cellular ammonia homeostasis, cellular creatinine homeostasis, cellular urea homeostasis, collecting duct development, distal tubule development, ductus arteriosus closure, fat cell differentiation, forelimb morphogenesis, glucose homeostasis, glucose metabolic process, hindlimb morphogenesis, kidney development, magnesium ion homeostasis, metanephric nephron development, negative regulation of apoptotic process, negative regulation of cell proliferation, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, phosphate ion homeostasis, positive regulation of cell proliferation, positive regulation of neuron apoptotic process, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of urine volume, potassium ion homeostasis, regulation of BMP signaling pathway, regulation of cell differentiation, regulation of insulin secretion, regulation of transcription, DNA-dependent, renal water homeostasis, retina layer formation, skin development, sodium ion homeostasis, sympathetic nervous system development nucleus DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II core promoter sequence-specific DNA binding, RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity, RNA polymerase II transcription coactivator activity, RNA polymerase II transcription corepressor activity, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, enhancer sequence-specific DNA binding, protein binding, protein dimerization activity, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, transcription corepressor activity Human TFAP2C BHF-UCL UniProtKB {GO:0005515=PMID:12586840, GO:0003700=PMID:9113991, GO:0021987=GO_REF:0000019, GO:0006357=PMID:9113991, GO:0060750=GO_REF:0000019, GO:0000981=GO_REF:0000019, GO:0007267=PMID:9113991, GO:0045682=GO_REF:0000019, GO:0021877=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0001829=GO_REF:0000019, GO:0003334=GO_REF:0000019, GO:0003677=PMID:12072434, GO:0060598=GO_REF:0000019, GO:0045944=PMID:22735262, GO:0048733=GO_REF:0000019, GO:0046983=PMID:12072434, GO:0000980=GO_REF:0000019, GO:0043588=GO_REF:0000019, GO:0030718=GO_REF:0000019, GO:0035019=GO_REF:0000019, GO:0001942=GO_REF:0000019, GO:0008584=PMID:17848411} Q92754 Transcription factor AP-2 gamma protein 20121129 {GO:0005515=IPI, GO:0003700=TAS, GO:0021987=IEA, GO:0006357=TAS, GO:0060750=IEA, GO:0000981=IEA, GO:0007267=TAS, GO:0045682=IEA, GO:0021877=IEA, GO:0005634=IEA, GO:0001829=IEA, GO:0003334=IEA, GO:0003677=IDA, GO:0060598=IEA, GO:0045944=IDA, GO:0048733=IEA, GO:0046983=IDA, GO:0000980=IEA, GO:0043588=IEA, GO:0030718=IEA, GO:0035019=IEA, GO:0001942=IEA, GO:0008584=IEP} cell-cell signaling, cerebral cortex development, dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis, epithelial cell proliferation involved in mammary gland duct elongation, forebrain neuron fate commitment, germ-line stem cell maintenance, hair follicle development, keratinocyte development, male gonad development, positive regulation of transcription from RNA polymerase II promoter, regulation of epidermis development, regulation of transcription from RNA polymerase II promoter, sebaceous gland development, skin development, somatic stem cell maintenance, trophectodermal cell differentiation nucleus DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding, protein binding, protein dimerization activity, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity Human TFAP2D ENSEMBL UniProtKB {GO:0005667=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0045893=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q7Z6R9 Transcription factor AP-2-delta protein 20130413 {GO:0005667=IEA, GO:0003700=IEA, GO:0045893=IEA, GO:0003677=IEA, GO:0006351=IEA} positive regulation of transcription, DNA-dependent, transcription, DNA-dependent transcription factor complex DNA binding, sequence-specific DNA binding transcription factor activity Human Ensembl:ENSMUSP00000037699 TFAP2E UniProtKB UniProtKB {GO:0003700=GO_REF:0000002, GO:0046982=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q6VUC0 Transcription factor AP-2-epsilon protein 20130413 {GO:0003700=IEA, GO:0046982=IEA, GO:0045944=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0042803=IEA, GO:0006351=IEA} positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0191 TFAP4 UniProtKB UniProtKB {GO:0005515=PMID:19505873, GO:0071157=PMID:18818310, GO:0008285=PMID:18818310, GO:0044212=PMID:16540471, GO:0042826=PMID:16540471, GO:0045736=PMID:18818310, GO:0003705=PMID:2833704, GO:0005634=PMID:19505873, GO:0042803=PMID:2123466, GO:0017053=GO_REF:0000024, GO:0046983=GO_REF:0000002, GO:0007090=PMID:18818310, GO:0006978=PMID:18818310, GO:0043066=GO_REF:0000019, GO:0043065=PMID:18818310, GO:0046982=PMID:2123466, GO:0003713=PMID:11171123, GO:0070888=PMID:18818310, GO:0003677=PMID:9931457, GO:0043923=PMID:2833704, GO:0043922=PMID:16540471, GO:0043392=PMID:16540471, GO:0043565=PMID:2123466, GO:0006461=PMID:19505873, GO:0045893=PMID:12663744, GO:0045892=PMID:16924111, GO:0071549=GO_REF:0000019} Q01664 Transcription factor AP-4 protein 20100401 {GO:0005515=IPI, GO:0071157=IMP, GO:0008285=IMP, GO:0044212=IDA, GO:0042826=IPI, GO:0045736=IDA, GO:0003705=IDA, GO:0005634=IDA, GO:0042803=IPI, GO:0017053=ISS, GO:0046983=IEA, GO:0007090=IDA, GO:0006978=IDA, GO:0043066=IEA, GO:0043065=IDA, GO:0046982=IMP, GO:0003713=IDA, GO:0070888=IDA, GO:0003677=IDA, GO:0043923=IDA, GO:0043922=IDA, GO:0043392=IDA, GO:0043565=IDA, GO:0006461=IDA, GO:0045893=IMP, GO:0045892=IDA, GO:0071549=IEA} DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, cellular response to dexamethasone stimulus, negative regulation by host of viral transcription, negative regulation of DNA binding, negative regulation of apoptotic process, negative regulation of cell cycle arrest, negative regulation of cell proliferation, negative regulation of cyclin-dependent protein serine/threonine kinase activity, negative regulation of transcription, DNA-dependent, positive regulation by host of viral transcription, positive regulation of apoptotic process, positive regulation of transcription, DNA-dependent, protein complex assembly, regulation of S phase of mitotic cell cycle nucleus, transcriptional repressor complex DNA binding, E-box binding, RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, histone deacetylase binding, protein binding, protein dimerization activity, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding, transcription coactivator activity, transcription regulatory region DNA binding Human UniProtKB:Q15853 TFB1M BHF-UCL UniProtKB {GO:0042645=PMID:18063578, GO:0005515=PMID:12897151, GO:0006355=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0000179=GO_REF:0000002} Q8WVM0 Dimethyladenosine transferase 1, mitochondrial protein 20090218 {GO:0042645=IDA, GO:0005515=IPI, GO:0006355=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0000179=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent mitochondrial nucleoid DNA binding, protein binding, rRNA (adenine-N6,N6-)-dimethyltransferase activity Human TFB2M BHF-UCL UniProtKB {GO:0042645=PMID:18063578, GO:0003712=PMID:12068295, GO:0010467=Reactome:REACT_71, GO:0005759=Reactome:REACT_268, GO:0006391=Reactome:REACT_367, GO:0006390=Reactome:REACT_1484, GO:0045893=PMID:20410300, GO:0000179=GO_REF:0000002} Q9H5Q4 Dimethyladenosine transferase 2, mitochondrial protein 20090218 {GO:0042645=IDA, GO:0003712=IDA, GO:0010467=TAS, GO:0005759=TAS, GO:0006391=TAS, GO:0006390=TAS, GO:0045893=IDA, GO:0000179=IEA} gene expression, positive regulation of transcription, DNA-dependent, transcription from mitochondrial promoter, transcription initiation from mitochondrial promoter mitochondrial matrix, mitochondrial nucleoid rRNA (adenine-N6,N6-)-dimethyltransferase activity, transcription cofactor activity Human TFCP2 PINC UniProtKB {GO:0003700=PMID:8157699, GO:0006357=PMID:8157699, GO:0005634=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q12800 Alpha-globin transcription factor CP2 protein 20030904 {GO:0003700=TAS, GO:0006357=TAS, GO:0005634=IEA, GO:0005575=ND, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cellular_component, nucleus DNA binding, sequence-specific DNA binding transcription factor activity Human TFCP2L1 HPA UniProtKB {GO:0007565=PMID:10644752, GO:0006694=PMID:10644752, GO:0003700=PMID:10644752, GO:0006357=PMID:10644752, GO:0003714=PMID:10644752, GO:0005730=GO_REF:0000052, GO:0000122=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0008340=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0005739=GO_REF:0000052, GO:0000902=GO_REF:0000019, GO:0016020=GO_REF:0000019, GO:0002070=GO_REF:0000019, GO:0007431=GO_REF:0000019, GO:0007028=GO_REF:0000019, GO:0045927=GO_REF:0000019} Q9NZI6 Transcription factor CP2-like protein 1 protein 20101115 {GO:0007565=TAS, GO:0006694=TAS, GO:0003700=TAS, GO:0006357=TAS, GO:0003714=TAS, GO:0005730=IDA, GO:0000122=IEA, GO:0003677=IEA, GO:0008340=IEA, GO:0006351=IEA, GO:0005739=IDA, GO:0000902=IEA, GO:0016020=IEA, GO:0002070=IEA, GO:0007431=IEA, GO:0007028=IEA, GO:0045927=IEA} cell morphogenesis, cytoplasm organization, determination of adult lifespan, epithelial cell maturation, female pregnancy, negative regulation of transcription from RNA polymerase II promoter, positive regulation of growth, regulation of transcription from RNA polymerase II promoter, salivary gland development, steroid biosynthetic process, transcription, DNA-dependent membrane, mitochondrion, nucleolus DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human TFDP1 InterPro UniProtKB {GO:0005515=PMID:16360038, GO:0010467=Reactome:REACT_71, GO:0005667=GO_REF:0000002, GO:0006367=Reactome:REACT_12627, GO:0003700=GO_REF:0000002, GO:0006357=PMID:8405995, GO:0008283=PMID:8405995, GO:0019904=PMID:16360038, GO:0003713=PMID:8405995, GO:0003677=GO_REF:0000037, GO:0006351=Reactome:REACT_121061, GO:0000082=Reactome:REACT_1783, GO:0045944=Reactome:REACT_120734, GO:0007179=Reactome:REACT_6844, GO:0005654=Reactome:REACT_121097, GO:0000080=Reactome:REACT_1590, GO:0000278=Reactome:REACT_152, GO:0008134=PMID:16360038} Q5JSB6 Transcription factor Dp-1 protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0005667=IEA, GO:0006367=TAS, GO:0003700=IEA, GO:0006357=TAS, GO:0008283=TAS, GO:0019904=IPI, GO:0003713=TAS, GO:0003677=IEA, GO:0006351=TAS, GO:0000082=TAS, GO:0045944=TAS, GO:0007179=TAS, GO:0005654=TAS, GO:0000080=TAS, GO:0000278=TAS, GO:0008134=IPI} G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, cell proliferation, gene expression, mitotic cell cycle, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway nucleoplasm, transcription factor complex DNA binding, protein binding, protein domain specific binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, transcription factor binding Human InterPro:IPR003316 TFDP2 Reactome UniProtKB {GO:0003712=PMID:7784053, GO:0010467=Reactome:REACT_71, GO:0005667=GO_REF:0000002, GO:0003700=GO_REF:0000019, GO:0006367=Reactome:REACT_12627, GO:0019904=PMID:16360038, GO:0003677=GO_REF:0000037, GO:0006351=Reactome:REACT_121061, GO:0007507=GO_REF:0000019, GO:0045944=Reactome:REACT_120734, GO:0005654=Reactome:REACT_121097, GO:0007179=Reactome:REACT_6844, GO:0000080=Reactome:REACT_1590, GO:0000278=Reactome:REACT_152, GO:0008134=PMID:16360038} Q14188 Transcription factor Dp-2 protein 20130301 {GO:0003712=TAS, GO:0010467=TAS, GO:0005667=IEA, GO:0003700=IEA, GO:0006367=TAS, GO:0019904=IPI, GO:0003677=IEA, GO:0006351=TAS, GO:0007507=IEA, GO:0045944=TAS, GO:0005654=TAS, GO:0007179=TAS, GO:0000080=TAS, GO:0000278=TAS, GO:0008134=IPI} G1 phase of mitotic cell cycle, gene expression, heart development, mitotic cell cycle, positive regulation of transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway nucleoplasm, transcription factor complex DNA binding, protein domain specific binding, sequence-specific DNA binding transcription factor activity, transcription cofactor activity, transcription factor binding Human TFDP3 UniProtKB UniProtKB {GO:0005667=GO_REF:0000002, GO:0000082=PMID:17062573, GO:0005737=PMID:17062573, GO:0003700=GO_REF:0000002, GO:0046982=PMID:17062573, GO:0003677=GO_REF:0000037, GO:0006974=PMID:20559320, GO:0006351=GO_REF:0000037} Q5H9I0 Transcription factor Dp family member 3 protein 20110815 {GO:0005667=IEA, GO:0000082=IDA, GO:0005737=IDA, GO:0003700=IEA, GO:0046982=IDA, GO:0003677=IEA, GO:0006974=IDA, GO:0006351=IEA} G1/S transition of mitotic cell cycle, response to DNA damage stimulus, transcription, DNA-dependent cytoplasm, transcription factor complex DNA binding, protein heterodimerization activity, sequence-specific DNA binding transcription factor activity Human TFE3 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0003700=GO_REF:0000024, GO:0044212=GO_REF:0000024, GO:0045944=GO_REF:0000024, GO:0006959=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0045670=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0045785=PMID:21209915} P19532 Transcription factor E3 protein 20100326 {GO:0005737=IDA, GO:0003700=ISS, GO:0044212=ISS, GO:0045944=ISS, GO:0006959=ISS, GO:0005730=IDA, GO:0046983=IEA, GO:0005634=IDA, GO:0045670=IEA, GO:0006351=IEA, GO:0045785=IMP} humoral immune response, positive regulation of cell adhesion, positive regulation of transcription from RNA polymerase II promoter, regulation of osteoclast differentiation, transcription, DNA-dependent cytoplasm, nucleolus, nucleus protein dimerization activity, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding Human TFEB ENSEMBL UniProtKB {GO:0005667=GO_REF:0000019, GO:0006355=PMID:2115126, GO:0003700=GO_REF:0000019, GO:0044212=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0006914=GO_REF:0000037, GO:0001892=GO_REF:0000002, GO:0005634=PMID:19556463, GO:0006351=GO_REF:0000037, GO:0005737=PMID:19556463, GO:0006959=GO_REF:0000002, GO:0045944=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0045893=GO_REF:0000002, GO:0007040=PMID:23434374, GO:0010508=PMID:23434374} Q709A9 Transcription factor EB protein 20130413 {GO:0005667=IEA, GO:0006355=NAS, GO:0003700=IEA, GO:0044212=IEA, GO:0046982=IEA, GO:0006914=IEA, GO:0001892=IEA, GO:0005634=IDA, GO:0006351=IEA, GO:0005737=IDA, GO:0006959=IEA, GO:0045944=IEA, GO:0046983=IEA, GO:0045893=IEA, GO:0007040=IMP, GO:0010508=IMP} autophagy, embryonic placenta development, humoral immune response, lysosome organization, positive regulation of autophagy, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus, transcription factor complex protein dimerization activity, protein heterodimerization activity, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding Human Ensembl:ENSMUSP00000024786 TFEC PINC UniProtKB {GO:0034605=GO_REF:0000019, GO:0006355=GO_REF:0000002, GO:0003700=PMID:9256061, GO:0003714=PMID:9256061, GO:0003713=PMID:9256061, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O14948 Transcription factor EC protein 20030904 {GO:0034605=IEA, GO:0006355=IEA, GO:0003700=TAS, GO:0003714=TAS, GO:0003713=TAS, GO:0046983=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} cellular response to heat, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, protein dimerization activity, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, transcription corepressor activity Human TFF1 BHF-UCL UniProtKB {GO:0005515=PMID:21982860, GO:0030277=GO_REF:0000019, GO:0005975=PMID:2303034, GO:0007586=PMID:9043862, GO:0010039=GO_REF:0000019, GO:0006950=GO_REF:0000019, GO:0043434=GO_REF:0000019, GO:0032355=PMID:15831516, GO:0005615=GO_REF:0000019, GO:0008083=GO_REF:0000037} P04155 Trefoil factor 1 protein 20080716 {GO:0005515=IPI, GO:0030277=IEA, GO:0005975=TAS, GO:0007586=NAS, GO:0010039=IEA, GO:0006950=IEA, GO:0043434=IEA, GO:0032355=IDA, GO:0005615=IEA, GO:0008083=IEA} carbohydrate metabolic process, digestion, maintenance of gastrointestinal epithelium, response to estradiol stimulus, response to iron ion, response to peptide hormone stimulus, response to stress extracellular space growth factor activity, protein binding Human TFF2 IntAct UniProtKB {GO:0005515=PMID:21982860, GO:0030334=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0070098=GO_REF:0000019, GO:0031723=GO_REF:0000019, GO:0019722=GO_REF:0000019, GO:0050728=GO_REF:0000019, GO:0043031=GO_REF:0000019, GO:0007586=PMID:9043862, GO:0060455=GO_REF:0000019, GO:0070374=GO_REF:0000019, GO:0005615=GO_REF:0000019} Q03403 Trefoil factor 2 protein 20130415 {GO:0005515=IPI, GO:0030334=IEA, GO:0008284=IEA, GO:0070098=IEA, GO:0031723=IEA, GO:0019722=IEA, GO:0050728=IEA, GO:0043031=IEA, GO:0007586=TAS, GO:0060455=IEA, GO:0070374=IEA, GO:0005615=IEA} calcium-mediated signaling, chemokine-mediated signaling pathway, digestion, negative regulation of gastric acid secretion, negative regulation of inflammatory response, negative regulation of macrophage activation, positive regulation of ERK1 and ERK2 cascade, positive regulation of cell proliferation, regulation of cell migration extracellular space CXCR4 chemokine receptor binding, protein binding Human UniProtKB:Q96PJ5 TFF3 PINC UniProtKB {GO:0003674=GO_REF:0000015, GO:0007586=PMID:9043862, GO:0006952=PMID:8454642, GO:0005576=PMID:8454642, GO:0032579=GO_REF:0000039} Q07654 Trefoil factor 3 protein 20030904 {GO:0003674=ND, GO:0007586=TAS, GO:0006952=TAS, GO:0005576=TAS, GO:0032579=IEA} defense response, digestion apical lamina of hyaline layer, extracellular region molecular_function Human TFG GOC UniProtKB {GO:0005515=PMID:16189514, GO:0007165=PMID:12761501, GO:0008219=GO_REF:0000037, GO:0005737=PMID:7565764, GO:0004871=PMID:12761501, GO:0043123=PMID:12761501, GO:0042802=GO_REF:0000019} Q92734 Protein TFG protein 20130413 {GO:0005515=IPI, GO:0007165=IMP, GO:0008219=IEA, GO:0005737=NAS, GO:0004871=IMP, GO:0043123=IMP, GO:0042802=IEA} cell death, positive regulation of I-kappaB kinase/NF-kappaB cascade, signal transduction cytoplasm identical protein binding, protein binding, signal transducer activity Human TFIP11 LIFEdb UniProtKB {GO:0006396=PMID:11991638, GO:0005737=GO_REF:0000039, GO:0006355=GO_REF:0000002, GO:0016607=GO_REF:0000054, GO:0000398=PMID:11991638, GO:0005578=GO_REF:0000019, GO:0005681=PMID:11991638, GO:0071013=PMID:11991638, GO:0003676=GO_REF:0000002, GO:0031214=GO_REF:0000037, GO:0003677=GO_REF:0000002} Q9UBB9 Tuftelin-interacting protein 11 protein 20100607 {GO:0006396=IC, GO:0005737=IEA, GO:0006355=IEA, GO:0016607=IDA, GO:0000398=IC, GO:0005578=IEA, GO:0005681=IDA, GO:0071013=IDA, GO:0003676=IEA, GO:0031214=IEA, GO:0003677=IEA} RNA processing, biomineral tissue development, mRNA splicing, via spliceosome, regulation of transcription, DNA-dependent catalytic step 2 spliceosome, cytoplasm, nuclear speck, proteinaceous extracellular matrix, spliceosomal complex DNA binding, nucleic acid binding Human TFPI GOC UniProtKB {GO:0010951=PMID:9252393, GO:0005886=Reactome:REACT_654, GO:0004866=PMID:9252393, GO:0005783=GO_REF:0000037, GO:0007596=Reactome:REACT_2051, GO:0004867=GO_REF:0000037, GO:0007598=Reactome:REACT_1573, GO:0031090=GO_REF:0000039, GO:0005576=Reactome:REACT_654, GO:0031225=GO_REF:0000037, GO:0005615=PMID:19065458} P10646 Tissue factor pathway inhibitor protein 20130413 {GO:0010951=TAS, GO:0005886=TAS, GO:0004866=TAS, GO:0005783=IEA, GO:0007596=TAS, GO:0004867=IEA, GO:0007598=TAS, GO:0031090=IEA, GO:0005576=TAS, GO:0031225=IEA, GO:0005615=IDA} blood coagulation, blood coagulation, extrinsic pathway, negative regulation of endopeptidase activity anchored to membrane, endoplasmic reticulum, extracellular region, extracellular space, organelle membrane, plasma membrane endopeptidase inhibitor activity, serine-type endopeptidase inhibitor activity Human TFPI2 PINC UniProtKB {GO:0007596=GO_REF:0000037, GO:0004867=GO_REF:0000037, GO:0005578=PMID:8914837, GO:0005201=PMID:8914837} P48307 Tissue factor pathway inhibitor 2 protein 20030904 {GO:0007596=IEA, GO:0004867=IEA, GO:0005578=TAS, GO:0005201=TAS} blood coagulation proteinaceous extracellular matrix extracellular matrix structural constituent, serine-type endopeptidase inhibitor activity Human TFPT IntAct UniProtKB {GO:0005515=PMID:17395368, GO:0006355=GO_REF:0000037, GO:0019901=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0005884=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000024, GO:0006310=GO_REF:0000037, GO:0006917=PMID:17041757, GO:0003677=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0031011=PMID:21303910, GO:0005737=GO_REF:0000024, GO:0006281=GO_REF:0000037} P0C1Z6 TCF3 fusion partner protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0019901=IEA, GO:0046982=IEA, GO:0005884=IEA, GO:0006915=IEA, GO:0005634=ISS, GO:0006310=IEA, GO:0006917=IDA, GO:0003677=ISS, GO:0006351=IEA, GO:0031011=IDA, GO:0005737=ISS, GO:0006281=IEA} DNA recombination, DNA repair, apoptotic process, induction of apoptosis, regulation of transcription, DNA-dependent, transcription, DNA-dependent Ino80 complex, actin filament, cytoplasm, nucleus DNA binding, protein binding, protein heterodimerization activity, protein kinase binding Human UniProtKB:Q96CJ1 TFR2 UniProtKB UniProtKB {GO:0006879=PMID:15319276, GO:0005737=GO_REF:0000039, GO:0005887=PMID:10409623, GO:0004998=PMID:10409623, GO:0006508=GO_REF:0000002, GO:0006826=PMID:10409623, GO:0008233=GO_REF:0000002} Q9UP52 Transferrin receptor protein 2 protein 20050711 {GO:0006879=TAS, GO:0005737=IEA, GO:0005887=NAS, GO:0004998=NAS, GO:0006508=IEA, GO:0006826=NAS, GO:0008233=IEA} cellular iron ion homeostasis, iron ion transport, proteolysis cytoplasm, integral to plasma membrane peptidase activity, transferrin receptor activity Human TFRC Reactome UniProtKB {GO:0005515=PMID:10638746, GO:0042470=GO_REF:0000039, GO:0048471=GO_REF:0000019, GO:0005886=Reactome:REACT_25389, GO:0030316=GO_REF:0000019, GO:0005576=PMID:1871153, GO:0055085=Reactome:REACT_15518, GO:0006879=Reactome:REACT_25060, GO:0033572=Reactome:REACT_25283, GO:0005905=PMID:12857860, GO:0016020=PMID:1871153, GO:0045780=GO_REF:0000019, GO:0004998=PMID:1871153, GO:0005887=PMID:6090955, GO:0019048=GO_REF:0000037, GO:0006508=GO_REF:0000002, GO:0016023=PMID:15229288, GO:0008233=GO_REF:0000002, GO:0009897=GO_REF:0000019, GO:0005768=PMID:14612438, GO:0070062=GO_REF:0000019} P02786 Transferrin receptor protein 1 protein 20121220 {GO:0005515=IPI, GO:0042470=IEA, GO:0048471=IEA, GO:0005886=TAS, GO:0030316=IEA, GO:0005576=IDA, GO:0055085=TAS, GO:0006879=TAS, GO:0033572=TAS, GO:0005905=IDA, GO:0016020=NAS, GO:0045780=IEA, GO:0004998=NAS, GO:0005887=TAS, GO:0019048=IEA, GO:0006508=IEA, GO:0016023=IDA, GO:0008233=IEA, GO:0009897=IEA, GO:0005768=IDA, GO:0070062=IEA} cellular iron ion homeostasis, osteoclast differentiation, positive regulation of bone resorption, proteolysis, transferrin transport, transmembrane transport, virus-host interaction coated pit, cytoplasmic membrane-bounded vesicle, endosome, external side of plasma membrane, extracellular region, extracellular vesicular exosome, integral to plasma membrane, melanosome, membrane, perinuclear region of cytoplasm, plasma membrane peptidase activity, protein binding, transferrin receptor activity Human TG PINC UniProtKB {GO:0004091=GO_REF:0000033, GO:0009986=GO_REF:0000033, GO:0045202=GO_REF:0000033, GO:0005576=PMID:14718574, GO:0030878=PMID:15494458, GO:0005615=GO_REF:0000033, GO:0007416=GO_REF:0000033, GO:0042043=GO_REF:0000033, GO:0007165=PMID:3016640, GO:0042403=GO_REF:0000019, GO:0005179=GO_REF:0000037, GO:0005887=GO_REF:0000033, GO:0031641=GO_REF:0000019, GO:0042446=GO_REF:0000037, GO:0004872=GO_REF:0000033, GO:0006590=GO_REF:0000033, GO:0015705=GO_REF:0000019} P01266 Thyroglobulin protein 20040512 {GO:0004091=IKR, GO:0009986=IRD, GO:0045202=IRD, GO:0005576=NAS, GO:0030878=IEP, GO:0005615=IBA, GO:0007416=IRD, GO:0042043=IRD, GO:0007165=NAS, GO:0042403=IEA, GO:0005179=IEA, GO:0005887=IRD, GO:0031641=IEA, GO:0042446=IEA, GO:0004872=IRD, GO:0006590=IBA, GO:0015705=IEA} hormone biosynthetic process, iodide transport, regulation of myelination, signal transduction, synapse assembly, thyroid gland development, thyroid hormone generation, thyroid hormone metabolic process cell surface, extracellular region, extracellular space, integral to plasma membrane, synapse carboxylesterase activity, hormone activity, neurexin family protein binding, receptor activity Human TGDS UniProtKB UniProtKB {GO:0050662=GO_REF:0000002, GO:0008460=GO_REF:0000003, GO:0009225=GO_REF:0000002} O95455 dTDP-D-glucose 4,6-dehydratase protein 20130413 {GO:0050662=IEA, GO:0008460=IEA, GO:0009225=IEA} nucleotide-sugar metabolic process coenzyme binding, dTDP-glucose 4,6-dehydratase activity Human EC:4.2.1.46 TGFA GOC UniProtKB {GO:0005515=PMID:15064403, GO:0005154=PMID:11278323, GO:0048471=PMID:15064403, GO:0005886=PMID:10918572, GO:0008283=PMID:10861448, GO:0005634=GO_REF:0000019, GO:0005615=PMID:12743035, GO:0000187=PMID:11278323, GO:0016323=PMID:17553928, GO:0001948=GO_REF:0000019, GO:0007173=GO_REF:0000019, GO:0000165=PMID:11278323, GO:0051781=GO_REF:0000037, GO:0004708=PMID:11278323, GO:0050679=PMID:11278323, GO:0043066=GO_REF:0000019, GO:0009986=PMID:12743035, GO:0042493=GO_REF:0000019, GO:0045741=PMID:11278323, GO:0045840=PMID:11278323, GO:0001525=GO_REF:0000019, GO:0031410=PMID:15064403, GO:0042060=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0008083=PMID:11278323, GO:0060749=GO_REF:0000019} P01135 Protransforming growth factor alpha protein 20130413 {GO:0005515=IPI, GO:0005154=IDA, GO:0048471=IDA, GO:0005886=NAS, GO:0008283=TAS, GO:0005634=IEA, GO:0005615=IDA, GO:0000187=IDA, GO:0016323=IDA, GO:0001948=IEA, GO:0007173=IEA, GO:0000165=IDA, GO:0051781=IEA, GO:0004708=IDA, GO:0050679=IDA, GO:0043066=IEA, GO:0009986=IDA, GO:0042493=IEA, GO:0045741=IDA, GO:0045840=IDA, GO:0001525=IEA, GO:0031410=IDA, GO:0042060=IEA, GO:0016021=IEA, GO:0008083=IDA, GO:0060749=IEA} MAPK cascade, activation of MAPK activity, angiogenesis, cell proliferation, epidermal growth factor receptor signaling pathway, mammary gland alveolus development, negative regulation of apoptotic process, positive regulation of cell division, positive regulation of epidermal growth factor-activated receptor activity, positive regulation of epithelial cell proliferation, positive regulation of mitosis, response to drug, wound healing basolateral plasma membrane, cell surface, cytoplasmic vesicle, extracellular space, integral to membrane, nucleus, perinuclear region of cytoplasm, plasma membrane MAP kinase kinase activity, epidermal growth factor receptor binding, glycoprotein binding, growth factor activity, protein binding Human TGFB1 BHF-UCL UniProtKB {GO:0005515=PMID:7852346, GO:0030308=PMID:15334054, GO:0002513=GO_REF:0000019, GO:0019058=Reactome:REACT_6167, GO:0009790=GO_REF:0000019, GO:0005615=PMID:19734317, GO:0045662=PMID:9770491, GO:0005114=PMID:1333888, GO:0042130=GO_REF:0000019, GO:0006754=PMID:10513816, GO:0002062=PMID:15040835, GO:0051152=GO_REF:0000019, GO:0000060=PMID:21390327, GO:0022408=PMID:18593713, GO:0048839=GO_REF:0000019, GO:0030501=PMID:17401695, GO:0002460=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0005796=Reactome:REACT_6931, GO:0010742=PMID:15219857, GO:0031536=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0048642=PMID:9770491, GO:0032270=PMID:15219857, GO:0010936=PMID:20875417, GO:0032967=PMID:19734317, GO:0016049=GO_REF:0000002, GO:0042306=GO_REF:0000024, GO:0030424=GO_REF:0000019, GO:0007093=PMID:15334054, GO:2000679=PMID:22073128, GO:0042482=GO_REF:0000019, GO:0050714=PMID:18505915, GO:0010718=PMID:21319131, GO:0005634=PMID:18040277, GO:0009817=GO_REF:0000019, GO:0001837=GO_REF:0000019, GO:0033138=PMID:18625725, GO:0051092=GO_REF:0000019, GO:0050921=PMID:18555217, GO:0043011=GO_REF:0000019, GO:0032930=PMID:22073128, GO:0007435=PMID:18080134, GO:0009314=GO_REF:0000019, GO:0032740=PMID:18453574, GO:0008354=GO_REF:0000019, GO:0060744=GO_REF:0000019, GO:0035307=PMID:14555988, GO:0042493=GO_REF:0000019, GO:0009611=PMID:18040277, GO:0010862=PMID:19736306, GO:0005578=GO_REF:0000024, GO:0048565=GO_REF:0000019, GO:0051098=GO_REF:0000024, GO:0005576=Reactome:REACT_160299, GO:1901666=PMID:22073128, GO:0005902=PMID:19366691, GO:0045066=GO_REF:0000019, GO:0031065=GO_REF:0000019, GO:0007492=GO_REF:0000019, GO:0060325=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0032801=PMID:17878231, GO:0002576=Reactome:REACT_318, GO:0070723=PMID:17878231, GO:0008156=PMID:11158066, GO:0061035=GO_REF:0000019, GO:0030214=PMID:17324121, GO:0032943=GO_REF:0000019, GO:0001657=GO_REF:0000019, GO:0008219=GO_REF:0000019, GO:0043932=PMID:17401695, GO:0070306=GO_REF:0000019, GO:0045599=PMID:15040835, GO:0060751=GO_REF:0000019, GO:0048298=PMID:14988498, GO:0050680=PMID:16943770, GO:0046732=Reactome:REACT_6213, GO:0006796=PMID:10513816, GO:0042803=GO_REF:0000019, GO:0007406=GO_REF:0000019, GO:0071158=GO_REF:0000019, GO:0048535=GO_REF:0000024, GO:0010763=PMID:18555217, GO:0043552=PMID:18625725, GO:0007173=PMID:18625725, GO:0030198=Reactome:REACT_118779, GO:0006611=PMID:17438144, GO:0043025=GO_REF:0000019, GO:0016202=GO_REF:0000024, GO:0051781=GO_REF:0000037, GO:0007179=PMID:11157754, GO:0017015=PMID:15334054, GO:0043029=GO_REF:0000019, GO:0032355=PMID:18039789, GO:0030334=PMID:19018011, GO:0050679=GO_REF:0000019, GO:0010800=PMID:18625725, GO:0007565=GO_REF:0000019, GO:0060762=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0045786=PMID:11502704, GO:0060391=PMID:9389648, GO:0045216=PMID:18505915, GO:0043536=PMID:18555217, GO:0007183=PMID:17438144, GO:0050777=GO_REF:0000019, GO:0045930=PMID:14555988, GO:0007184=PMID:15334054, GO:0051101=GO_REF:0000024, GO:0002028=GO_REF:0000019, GO:0032570=PMID:18039789, GO:0060389=PMID:11157754, GO:0019899=PMID:19366691, GO:0045893=PMID:9389648, GO:0008083=GO_REF:0000037, GO:0045892=PMID:15702480, GO:0043537=PMID:18555217, GO:0051897=PMID:18625725, GO:0008284=PMID:10513816, GO:0008285=PMID:15334054, GO:0031100=GO_REF:0000019, GO:0033280=GO_REF:0000019, GO:0035066=GO_REF:0000019, GO:0085029=PMID:19734317, GO:0050765=GO_REF:0000019, GO:0005737=PMID:18040277, GO:0030279=GO_REF:0000019, GO:0043406=PMID:18625725, GO:0002244=PMID:15451575, GO:0045944=PMID:18832382, GO:0007050=PMID:14555988, GO:0031093=Reactome:REACT_21351, GO:0051280=GO_REF:0000019, GO:0090190=GO_REF:0000019, GO:0030512=Reactome:REACT_120727, GO:0001666=GO_REF:0000019, GO:0042552=GO_REF:0000019, GO:0006874=GO_REF:0000019, GO:0002248=PMID:9639571, GO:0006917=PMID:15334054, GO:0009749=GO_REF:0000019, GO:0010628=PMID:18625725, GO:0060364=GO_REF:0000019, GO:0047485=GO_REF:0000019, GO:0034616=GO_REF:0000019, GO:0019048=Reactome:REACT_6323, GO:0019049=PMID:15334054, GO:0001934=PMID:18625725, GO:0001933=PMID:8053900, GO:0006468=GO_REF:0000024, GO:0071549=GO_REF:0000019} P01137 Transforming growth factor beta-1 protein 20121121 {GO:0005515=IPI, GO:0030308=IDA, GO:0002513=IEA, GO:0019058=TAS, GO:0009790=IEA, GO:0005615=IDA, GO:0045662=IDA, GO:0005114=IPI, GO:0042130=IEA, GO:0006754=IDA, GO:0002062=IDA, GO:0051152=IEA, GO:0000060=IDA, GO:0022408=IDA, GO:0048839=IEA, GO:0030501=IEP, GO:0002460=IEA, GO:0046982=IEA, GO:0009986=IEA, GO:0005796=TAS, GO:0010742=IC, GO:0031536=IEA, GO:0030168=TAS, GO:0048642=IDA, GO:0032270=IDA, GO:0010936=IDA, GO:0032967=IDA, GO:0016049=IEA, GO:0042306=ISS, GO:0030424=IEA, GO:0007093=IDA, GO:2000679=IDA, GO:0042482=IEA, GO:0050714=IDA, GO:0010718=NAS, GO:0005634=IDA, GO:0009817=IEA, GO:0001837=IEA, GO:0033138=IDA, GO:0051092=IEA, GO:0050921=IDA, GO:0043011=IEA, GO:0032930=IDA, GO:0007435=IEP, GO:0009314=IEA, GO:0032740=IDA, GO:0008354=IEA, GO:0060744=IEA, GO:0035307=IDA, GO:0042493=IEA, GO:0009611=IEP, GO:0010862=IDA, GO:0005578=ISS, GO:0048565=IEA, GO:0051098=ISS, GO:0005576=TAS, GO:1901666=IDA, GO:0005902=IDA, GO:0045066=IEA, GO:0031065=IEA, GO:0007492=IEA, GO:0060325=IEA, GO:0007596=TAS, GO:0032801=IDA, GO:0002576=TAS, GO:0070723=IDA, GO:0008156=IMP, GO:0061035=IEA, GO:0030214=IDA, GO:0032943=IEA, GO:0001657=IEA, GO:0008219=IEA, GO:0043932=IEP, GO:0070306=IEA, GO:0045599=IDA, GO:0060751=IEA, GO:0048298=IDA, GO:0050680=IMP, GO:0046732=TAS, GO:0006796=IDA, GO:0042803=IEA, GO:0007406=IEA, GO:0071158=IEA, GO:0048535=ISS, GO:0010763=IDA, GO:0043552=IDA, GO:0007173=IDA, GO:0030198=TAS, GO:0006611=IDA, GO:0043025=IEA, GO:0016202=ISS, GO:0051781=IEA, GO:0007179=IDA, GO:0017015=IDA, GO:0043029=IEA, GO:0032355=IDA, GO:0030334=TAS, GO:0050679=IEA, GO:0010800=IDA, GO:0007565=IEA, GO:0060762=IEA, GO:0007568=IEA, GO:0000122=IEA, GO:0045786=IDA, GO:0060391=IDA, GO:0045216=IDA, GO:0043536=IDA, GO:0007183=IDA, GO:0050777=IEA, GO:0045930=IDA, GO:0007184=IDA, GO:0051101=ISS, GO:0002028=IEA, GO:0032570=IDA, GO:0060389=IDA, GO:0019899=IPI, GO:0045893=IDA, GO:0008083=IEA, GO:0045892=IDA, GO:0043537=IDA, GO:0051897=IDA, GO:0008284=IDA, GO:0008285=IDA, GO:0031100=IEA, GO:0033280=IEA, GO:0035066=IEA, GO:0085029=IDA, GO:0050765=IEA, GO:0005737=IDA, GO:0030279=IEA, GO:0043406=IDA, GO:0002244=IDA, GO:0045944=IDA, GO:0007050=IDA, GO:0031093=TAS, GO:0051280=IEA, GO:0090190=IEA, GO:0030512=TAS, GO:0001666=IEA, GO:0042552=IEA, GO:0006874=IEA, GO:0002248=TAS, GO:0006917=IDA, GO:0009749=IEA, GO:0010628=IDA, GO:0060364=IEA, GO:0047485=IEA, GO:0034616=IEA, GO:0019048=TAS, GO:0019049=IDA, GO:0001934=IDA, GO:0001933=IDA, GO:0006468=ISS, GO:0071549=IEA} ATP biosynthetic process, SMAD protein complex assembly, SMAD protein import into nucleus, T cell homeostasis, active induction of host immune response by virus, adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, aging, blood coagulation, branch elongation involved in mammary gland duct branching, cell cycle arrest, cell death, cell growth, cell-cell junction organization, cellular calcium ion homeostasis, cellular response to dexamethasone stimulus, chondrocyte differentiation, connective tissue replacement involved in inflammatory response wound healing, defense response to fungus, incompatible interaction, digestive tract development, embryo development, endoderm development, epidermal growth factor receptor signaling pathway, epithelial to mesenchymal transition, evasion or tolerance of host defenses by virus, extracellular matrix assembly, extracellular matrix organization, face morphogenesis, female pregnancy, frontal suture morphogenesis, germ cell migration, hematopoietic progenitor cell differentiation, hyaluronan catabolic process, induction of apoptosis, inner ear development, lens fiber cell differentiation, lymph node development, macrophage derived foam cell differentiation, mammary gland branching involved in thelarche, mitotic cell cycle checkpoint, mononuclear cell proliferation, myelination, myeloid dendritic cell differentiation, negative regulation of DNA replication, negative regulation of T cell proliferation, negative regulation of blood vessel endothelial cell migration, negative regulation of cell cycle, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of cell-cell adhesion, negative regulation of epithelial cell proliferation, negative regulation of fat cell differentiation, negative regulation of immune response, negative regulation of macrophage cytokine production, negative regulation of mitotic cell cycle, negative regulation of myoblast differentiation, negative regulation of neuroblast proliferation, negative regulation of ossification, negative regulation of phagocytosis, negative regulation of protein phosphorylation, negative regulation of release of sequestered calcium ion into cytosol, negative regulation of skeletal muscle tissue development, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, negative regulation of transforming growth factor beta receptor signaling pathway, organ regeneration, ossification involved in bone remodeling, pathway-restricted SMAD protein phosphorylation, phosphate-containing compound metabolic process, platelet activation, platelet degranulation, positive regulation of MAP kinase activity, positive regulation of NAD+ ADP-ribosyltransferase activity, positive regulation of NF-kappaB transcription factor activity, positive regulation of SMAD protein import into nucleus, positive regulation of blood vessel endothelial cell migration, positive regulation of bone mineralization, positive regulation of branching involved in ureteric bud morphogenesis, positive regulation of cell cycle arrest, positive regulation of cell division, positive regulation of cell proliferation, positive regulation of cellular protein metabolic process, positive regulation of chemotaxis, positive regulation of collagen biosynthetic process, positive regulation of epithelial cell proliferation, positive regulation of epithelial to mesenchymal transition, positive regulation of exit from mitosis, positive regulation of fibroblast migration, positive regulation of gene expression, positive regulation of histone acetylation, positive regulation of histone deacetylation, positive regulation of interleukin-17 production, positive regulation of isotype switching to IgA isotypes, positive regulation of odontogenesis, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of peptidyl-serine phosphorylation, positive regulation of peptidyl-threonine phosphorylation, positive regulation of phosphatidylinositol 3-kinase activity, positive regulation of protein dephosphorylation, positive regulation of protein kinase B signaling cascade, positive regulation of protein phosphorylation, positive regulation of protein secretion, positive regulation of smooth muscle cell differentiation, positive regulation of superoxide anion generation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription regulatory region DNA binding, positive regulation of transcription, DNA-dependent, protein export from nucleus, protein import into nucleus, translocation, protein phosphorylation, receptor catabolic process, regulation of DNA binding, regulation of binding, regulation of branching involved in mammary gland duct morphogenesis, regulation of cartilage development, regulation of cell migration, regulation of protein import into nucleus, regulation of sodium ion transport, regulation of striated muscle tissue development, regulation of transforming growth factor beta receptor signaling pathway, regulatory T cell differentiation, response to cholesterol, response to drug, response to estradiol stimulus, response to glucose stimulus, response to hypoxia, response to laminar fluid shear stress, response to progesterone stimulus, response to radiation, response to vitamin D, response to wounding, salivary gland morphogenesis, tolerance induction to self antigen, transforming growth factor beta receptor signaling pathway, ureteric bud development, viral infectious cycle, virus-host interaction Golgi lumen, axon, cell surface, cytoplasm, extracellular region, extracellular space, microvillus, neuronal cell body, nucleus, platelet alpha granule lumen, proteinaceous extracellular matrix enzyme binding, growth factor activity, protein N-terminus binding, protein binding, protein heterodimerization activity, protein homodimerization activity, type II transforming growth factor beta receptor binding Human TGFB1I1 BHF-UCL UniProtKB {GO:0005515=PMID:10604475, GO:0008285=PMID:7929412, GO:0009408=GO_REF:0000019, GO:0006366=PMID:10075738, GO:0045599=GO_REF:0000019, GO:0010718=PMID:18762808, GO:0050681=PMID:10075738, GO:0048495=PMID:19855388, GO:0016363=GO_REF:0000039, GO:0005622=PMID:10075738, GO:0005737=GO_REF:0000037, GO:0030855=GO_REF:0000019, GO:0005856=GO_REF:0000039, GO:0016055=GO_REF:0000037, GO:0007155=PMID:9422762, GO:0030579=PMID:18762808, GO:0030512=PMID:18762808, GO:0030511=PMID:18762808, GO:0003713=PMID:15572661, GO:0070411=PMID:18762808, GO:0045165=GO_REF:0000019, GO:0016331=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0045893=PMID:10075738, GO:0005925=GO_REF:0000039, GO:0030521=PMID:15572661} O43294 Transforming growth factor beta-1-induced transcript 1 protein protein 20100311 {GO:0005515=IPI, GO:0008285=TAS, GO:0009408=IEA, GO:0006366=TAS, GO:0045599=IEA, GO:0010718=IDA, GO:0050681=IPI, GO:0048495=IPI, GO:0016363=IEA, GO:0005622=IDA, GO:0005737=IEA, GO:0030855=IEA, GO:0005856=IEA, GO:0016055=IEA, GO:0007155=TAS, GO:0030579=IDA, GO:0030512=IDA, GO:0030511=IDA, GO:0003713=NAS, GO:0070411=IPI, GO:0045165=IEA, GO:0016331=IEA, GO:0008270=IEA, GO:0045893=IDA, GO:0005925=IEA, GO:0030521=NAS} Wnt receptor signaling pathway, androgen receptor signaling pathway, cell adhesion, cell fate commitment, epithelial cell differentiation, morphogenesis of embryonic epithelium, negative regulation of cell proliferation, negative regulation of fat cell differentiation, negative regulation of transforming growth factor beta receptor signaling pathway, positive regulation of epithelial to mesenchymal transition, positive regulation of transcription, DNA-dependent, positive regulation of transforming growth factor beta receptor signaling pathway, response to heat, transcription from RNA polymerase II promoter, ubiquitin-dependent SMAD protein catabolic process cytoplasm, cytoskeleton, focal adhesion, intracellular, nuclear matrix I-SMAD binding, Roundabout binding, androgen receptor binding, protein binding, transcription coactivator activity, zinc ion binding Human UniProtKB:O15105 TGFB2 GOC UniProtKB {GO:0005515=PMID:11157754, GO:0008219=PMID:16227582, GO:0030308=PMID:18358889, GO:0030307=PMID:20573232, GO:0001654=PMID:15944186, GO:0050680=PMID:16943770, GO:0009790=PMID:2119582, GO:0005615=GO_REF:0000019, GO:0042803=PMID:2119582, GO:0005114=PMID:1333888, GO:0031069=GO_REF:0000024, GO:0007507=PMID:15896309, GO:0043525=PMID:16227582, GO:0004702=PMID:12958365, GO:0030198=Reactome:REACT_118779, GO:0007411=GO_REF:0000019, GO:0030199=PMID:16891397, GO:0043025=GO_REF:0000024, GO:0007179=PMID:18358889, GO:0051781=GO_REF:0000037, GO:0001942=PMID:10433821, GO:0045823=PMID:15896309, GO:0023014=PMID:12958365, GO:0046982=PMID:9611771, GO:0030593=GO_REF:0000024, GO:0030168=Reactome:REACT_798, GO:0014068=PMID:18223299, GO:0045787=GO_REF:0000024, GO:0005125=PMID:9611771, GO:0005160=PMID:10092230, GO:0045216=PMID:18505915, GO:0060038=PMID:15896309, GO:0042637=PMID:15955085, GO:0010936=PMID:20875417, GO:0050777=PMID:9611771, GO:0001502=GO_REF:0000019, GO:0050778=GO_REF:0000024, GO:0007184=PMID:17192487, GO:0042060=GO_REF:0000024, GO:0032570=PMID:18039789, GO:0010002=PMID:15896309, GO:0016049=GO_REF:0000002, GO:0060389=PMID:18358889, GO:0008083=GO_REF:0000037, GO:0051795=PMID:15955085, GO:0030424=GO_REF:0000024, GO:0048103=GO_REF:0000024, GO:0008284=PMID:15896309, GO:0008285=PMID:15944186, GO:0008347=PMID:18431253, GO:0008283=PMID:3322813, GO:0050714=PMID:18505915, GO:0007267=PMID:3322813, GO:0048699=PMID:15944186, GO:0010718=PMID:17999987, GO:0032874=PMID:17192487, GO:0001837=PMID:10092230, GO:0051891=PMID:15896309, GO:0045778=PMID:17401695, GO:0006924=GO_REF:0000019, GO:0010693=PMID:18358889, GO:0032147=PMID:17960115, GO:0042416=GO_REF:0000024, GO:0060317=PMID:10092230, GO:0001540=PMID:16227582, GO:0048666=GO_REF:0000024, GO:0042476=PMID:18078367, GO:0007050=PMID:18223299, GO:0022601=PMID:18039789, GO:0031093=Reactome:REACT_21351, GO:0007435=PMID:18080134, GO:0030097=GO_REF:0000024, GO:0001666=PMID:12411310, GO:0043065=PMID:17217916, GO:0033630=PMID:18223299, GO:0009611=PMID:18040277, GO:0005102=PMID:16227582, GO:0005576=Reactome:REACT_150269, GO:0045726=PMID:17960115, GO:0006917=GO_REF:0000019, GO:0048663=GO_REF:0000019, GO:0048566=PMID:20875417, GO:0001525=PMID:9611771, GO:0031012=PMID:18049952, GO:0010628=GO_REF:0000019, GO:0000902=PMID:15896309, GO:0003007=PMID:10092230, GO:0032909=PMID:12411310, GO:0016477=PMID:10092230, GO:0060325=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0001974=GO_REF:0000019, GO:0002576=Reactome:REACT_318, GO:0006468=PMID:18358889, GO:0010634=PMID:17960115} P61812 Transforming growth factor beta-2 protein 20130413 {GO:0005515=IPI, GO:0008219=IDA, GO:0030308=IDA, GO:0030307=IDA, GO:0001654=IDA, GO:0050680=IMP, GO:0009790=TAS, GO:0005615=IEA, GO:0042803=IDA, GO:0005114=IPI, GO:0031069=ISS, GO:0007507=IDA, GO:0043525=IDA, GO:0004702=IDA, GO:0030198=TAS, GO:0007411=IEA, GO:0030199=IDA, GO:0043025=ISS, GO:0007179=IDA, GO:0051781=IEA, GO:0001942=IDA, GO:0045823=IDA, GO:0023014=IDA, GO:0046982=TAS, GO:0030593=ISS, GO:0030168=TAS, GO:0014068=IDA, GO:0045787=ISS, GO:0005125=TAS, GO:0005160=IDA, GO:0045216=IDA, GO:0060038=IDA, GO:0042637=IDA, GO:0010936=IDA, GO:0050777=TAS, GO:0001502=IEA, GO:0050778=ISS, GO:0007184=IDA, GO:0042060=ISS, GO:0032570=IDA, GO:0010002=IDA, GO:0016049=IEA, GO:0060389=IDA, GO:0008083=IEA, GO:0051795=IDA, GO:0030424=ISS, GO:0048103=ISS, GO:0008284=IDA, GO:0008285=IDA, GO:0008347=IDA, GO:0008283=TAS, GO:0050714=IDA, GO:0007267=TAS, GO:0048699=TAS, GO:0010718=IDA, GO:0032874=IDA, GO:0001837=IDA, GO:0051891=IDA, GO:0045778=IEP, GO:0006924=IEA, GO:0010693=IDA, GO:0032147=IDA, GO:0042416=ISS, GO:0060317=IDA, GO:0001540=IDA, GO:0048666=ISS, GO:0042476=NAS, GO:0007050=IDA, GO:0022601=IEP, GO:0031093=TAS, GO:0007435=IEP, GO:0030097=ISS, GO:0001666=IMP, GO:0043065=IDA, GO:0033630=IDA, GO:0009611=IEP, GO:0005102=IMP, GO:0005576=TAS, GO:0045726=IDA, GO:0006917=IEA, GO:0048663=IEA, GO:0048566=IEP, GO:0001525=TAS, GO:0031012=IDA, GO:0010628=IEA, GO:0000902=IDA, GO:0003007=IDA, GO:0032909=IMP, GO:0016477=IDA, GO:0060325=IEA, GO:0007596=TAS, GO:0001974=IEA, GO:0002576=TAS, GO:0006468=IDA, GO:0010634=IDA} SMAD protein import into nucleus, activation of protein kinase activity, activation-induced cell death of T cells, angiogenesis, axon guidance, blood coagulation, blood vessel remodeling, cardiac epithelial to mesenchymal transition, cardiac muscle cell proliferation, cardioblast differentiation, cartilage condensation, catagen, cell cycle arrest, cell death, cell growth, cell migration, cell morphogenesis, cell proliferation, cell-cell junction organization, cell-cell signaling, collagen fibril organization, dopamine biosynthetic process, embryo development, embryonic digestive tract development, epithelial to mesenchymal transition, extracellular matrix organization, eye development, face morphogenesis, generation of neurons, glial cell migration, hair follicle development, hair follicle morphogenesis, heart development, heart morphogenesis, hemopoiesis, induction of apoptosis, menstrual cycle phase, negative regulation of alkaline phosphatase activity, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of epithelial cell proliferation, negative regulation of immune response, negative regulation of macrophage cytokine production, neuron development, neuron fate commitment, neutrophil chemotaxis, odontogenesis, pathway-restricted SMAD protein phosphorylation, platelet activation, platelet degranulation, positive regulation of apoptotic process, positive regulation of cardioblast differentiation, positive regulation of catagen, positive regulation of cell adhesion mediated by integrin, positive regulation of cell cycle, positive regulation of cell division, positive regulation of cell growth, positive regulation of cell proliferation, positive regulation of epithelial cell migration, positive regulation of epithelial to mesenchymal transition, positive regulation of gene expression, positive regulation of heart contraction, positive regulation of immune response, positive regulation of integrin biosynthetic process, positive regulation of neuron apoptotic process, positive regulation of ossification, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of protein secretion, positive regulation of stress-activated MAPK cascade, protein phosphorylation, regulation of transforming growth factor beta2 production, response to hypoxia, response to progesterone stimulus, response to wounding, salivary gland morphogenesis, signal transduction by phosphorylation, somatic stem cell division, transforming growth factor beta receptor signaling pathway, wound healing axon, extracellular matrix, extracellular region, extracellular space, neuronal cell body, platelet alpha granule lumen beta-amyloid binding, cytokine activity, growth factor activity, protein binding, protein heterodimerization activity, protein homodimerization activity, receptor binding, receptor signaling protein serine/threonine kinase activity, transforming growth factor beta receptor binding, type II transforming growth factor beta receptor binding Human TGFB3 ENSEMBL UniProtKB {GO:0005515=PMID:7852346, GO:0043627=GO_REF:0000019, GO:0043932=PMID:17401695, GO:0051491=GO_REF:0000019, GO:0030879=GO_REF:0000019, GO:0048702=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0005114=PMID:1333888, GO:0042802=PMID:18243111, GO:0043524=GO_REF:0000019, GO:0030198=Reactome:REACT_118779, GO:0043025=GO_REF:0000019, GO:0051781=GO_REF:0000037, GO:0007179=PMID:11157754, GO:0048839=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:0030501=PMID:17401695, GO:0048286=GO_REF:0000019, GO:0046982=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0045740=PMID:11158066, GO:0007568=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0005160=GO_REF:0000002, GO:0001701=GO_REF:0000019, GO:0060391=GO_REF:0000019, GO:0045216=PMID:18505915, GO:0010936=PMID:20875417, GO:0070483=PMID:18156205, GO:0032967=PMID:11158066, GO:0007184=GO_REF:0000019, GO:0042060=GO_REF:0000019, GO:0032570=PMID:18039789, GO:0016049=GO_REF:0000002, GO:0045893=GO_REF:0000024, GO:0008083=GO_REF:0000038, GO:0008285=GO_REF:0000019, GO:0005886=PMID:11157754, GO:0050714=PMID:18505915, GO:0010718=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0000187=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0042476=PMID:18078367, GO:0060021=GO_REF:0000019, GO:0031093=Reactome:REACT_21351, GO:0022601=PMID:18039789, GO:0030141=GO_REF:0000019, GO:0007435=PMID:18080134, GO:0030512=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0050431=PMID:18243111, GO:0010862=GO_REF:0000019, GO:0030315=GO_REF:0000019, GO:0005576=Reactome:REACT_150337, GO:0048565=GO_REF:0000019, GO:0006917=GO_REF:0000019, GO:0031012=GO_REF:0000019, GO:0060364=GO_REF:0000019, GO:0071363=GO_REF:0000019, GO:0034713=PMID:18243111, GO:0060325=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0034616=GO_REF:0000019, GO:0002576=Reactome:REACT_318, GO:0008156=PMID:11158066} Q8WV88 Transforming growth factor beta-3 protein 20130413 {GO:0005515=IPI, GO:0043627=IEA, GO:0043932=IEP, GO:0051491=IEA, GO:0030879=IEA, GO:0048702=IEA, GO:0005615=IEA, GO:0005114=IPI, GO:0042802=IDA, GO:0043524=IEA, GO:0030198=TAS, GO:0043025=IEA, GO:0051781=IEA, GO:0007179=IDA, GO:0048839=IEA, GO:0007565=IEA, GO:0030501=IEP, GO:0048286=IEA, GO:0046982=IEA, GO:0009986=IEA, GO:0045740=IMP, GO:0007568=IEA, GO:0030168=TAS, GO:0005160=IEA, GO:0001701=IEA, GO:0060391=IEA, GO:0045216=IDA, GO:0010936=IDA, GO:0070483=IDA, GO:0032967=IMP, GO:0007184=IEA, GO:0042060=IEA, GO:0032570=IDA, GO:0016049=IEA, GO:0045893=ISS, GO:0008083=IEA, GO:0008285=IEA, GO:0005886=IC, GO:0050714=IDA, GO:0010718=IEA, GO:0005634=IEA, GO:0000187=IEA, GO:0045944=IEA, GO:0042476=NAS, GO:0060021=IEA, GO:0031093=TAS, GO:0022601=IEP, GO:0030141=IEA, GO:0007435=IEP, GO:0030512=IEA, GO:0001666=IEA, GO:0050431=IDA, GO:0010862=IEA, GO:0030315=IEA, GO:0005576=TAS, GO:0048565=IEA, GO:0006917=IEA, GO:0031012=IEA, GO:0060364=IEA, GO:0071363=IEA, GO:0034713=IDA, GO:0060325=IEA, GO:0007596=TAS, GO:0034616=IEA, GO:0002576=TAS, GO:0008156=IMP} SMAD protein import into nucleus, activation of MAPK activity, aging, blood coagulation, cell growth, cell-cell junction organization, cellular response to growth factor stimulus, detection of hypoxia, digestive tract development, embryonic neurocranium morphogenesis, extracellular matrix organization, face morphogenesis, female pregnancy, frontal suture morphogenesis, in utero embryonic development, induction of apoptosis, inner ear development, lung alveolus development, mammary gland development, menstrual cycle phase, negative regulation of DNA replication, negative regulation of cell proliferation, negative regulation of macrophage cytokine production, negative regulation of neuron apoptotic process, negative regulation of transforming growth factor beta receptor signaling pathway, odontogenesis, ossification involved in bone remodeling, palate development, platelet activation, platelet degranulation, positive regulation of DNA replication, positive regulation of SMAD protein import into nucleus, positive regulation of bone mineralization, positive regulation of cell division, positive regulation of collagen biosynthetic process, positive regulation of epithelial to mesenchymal transition, positive regulation of filopodium assembly, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of protein secretion, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, response to estrogen stimulus, response to hypoxia, response to laminar fluid shear stress, response to progesterone stimulus, salivary gland morphogenesis, transforming growth factor beta receptor signaling pathway, wound healing T-tubule, cell surface, extracellular matrix, extracellular region, extracellular space, neuronal cell body, nucleus, plasma membrane, platelet alpha granule lumen, secretory granule growth factor activity, identical protein binding, protein binding, protein heterodimerization activity, transforming growth factor beta binding, transforming growth factor beta receptor binding, type I transforming growth factor beta receptor binding, type II transforming growth factor beta receptor binding Human Ensembl:ENSMUSP00000003687 TGFBI BHF-UCL UniProtKB {GO:0005886=Reactome:REACT_75905, GO:0008283=PMID:1388724, GO:0005578=GO_REF:0000039, GO:0050840=GO_REF:0000019, GO:0005576=Reactome:REACT_75876, GO:0001525=PMID:11866539, GO:0005615=GO_REF:0000019, GO:0031012=PMID:22261194, GO:0007162=PMID:8024701, GO:0005178=PMID:1388724, GO:0030198=GO_REF:0000019, GO:0007155=GO_REF:0000019, GO:0007601=GO_REF:0000037, GO:0050896=GO_REF:0000037} Q15582 Transforming growth factor-beta-induced protein ig-h3 protein 20120228 {GO:0005886=TAS, GO:0008283=TAS, GO:0005578=IEA, GO:0050840=IEA, GO:0005576=TAS, GO:0001525=IEP, GO:0005615=IEA, GO:0031012=ISS, GO:0007162=TAS, GO:0005178=TAS, GO:0030198=IEA, GO:0007155=IEA, GO:0007601=IEA, GO:0050896=IEA} angiogenesis, cell adhesion, cell proliferation, extracellular matrix organization, negative regulation of cell adhesion, response to stimulus, visual perception extracellular matrix, extracellular region, extracellular space, plasma membrane, proteinaceous extracellular matrix extracellular matrix binding, integrin binding colocalizes_with Human UniProtKB:O11780 TGFBR1 BHF-UCL UniProtKB {GO:0010468=GO_REF:0000019, GO:0005515=PMID:18974388, GO:0030307=PMID:18625725, GO:0048705=GO_REF:0000024, GO:0051491=GO_REF:0000019, GO:0048844=GO_REF:0000024, GO:0048538=GO_REF:0000024, GO:0046332=PMID:8980228, GO:0009791=GO_REF:0000019, GO:0048701=GO_REF:0000024, GO:0005114=PMID:1333888, GO:0007507=GO_REF:0000024, GO:0070022=PMID:1326540, GO:0018105=PMID:12015308, GO:0018107=PMID:12015308, GO:0030199=GO_REF:0000024, GO:0007179=PMID:1326540, GO:0031396=PMID:18758450, GO:0043393=GO_REF:0000019, GO:0001701=GO_REF:0000024, GO:0060391=PMID:9389648, GO:0060037=GO_REF:0000024, GO:0043235=PMID:8774881, GO:0001501=GO_REF:0000024, GO:0043542=GO_REF:0000019, GO:0042060=PMID:9759503, GO:0060389=PMID:19736306, GO:0005923=PMID:15761148, GO:0045893=PMID:9389648, GO:0051897=PMID:18625725, GO:0008284=PMID:14633705, GO:0005886=PMID:17878231, GO:0001837=PMID:15761148, GO:0009952=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0000186=PMID:18625725, GO:0019838=PMID:14517293, GO:0002088=GO_REF:0000019, GO:0048870=PMID:18625725, GO:0005024=PMID:1326540, GO:0060021=GO_REF:0000024, GO:0007050=PMID:9759503, GO:0032331=GO_REF:0000024, GO:0005025=PMID:8752209, GO:0030512=Reactome:REACT_120727, GO:0043066=PMID:18625725, GO:0008354=GO_REF:0000024, GO:0050431=PMID:1326540, GO:0006355=PMID:14517293, GO:0001822=GO_REF:0000024, GO:0043062=PMID:9759503, GO:0001824=GO_REF:0000019, GO:0048762=PMID:9759503, GO:0010862=PMID:9389648, GO:0070411=PMID:11278251, GO:0006915=GO_REF:0000037, GO:0042981=PMID:18758450, GO:0048663=GO_REF:0000024, GO:0001525=GO_REF:0000019, GO:0006917=GO_REF:0000019, GO:0005524=PMID:12065756, GO:0007165=PMID:14633705, GO:0060017=GO_REF:0000024, GO:0016020=GO_REF:0000002, GO:0001937=GO_REF:0000019, GO:0004674=PMID:18625725, GO:0004675=PMID:12015308, GO:0070723=PMID:17878231, GO:0006468=PMID:12065756, GO:0051272=PMID:18625725} P36897 TGF-beta receptor type-1 protein 20120312 {GO:0010468=IEA, GO:0005515=IPI, GO:0030307=IDA, GO:0048705=ISS, GO:0051491=IEA, GO:0048844=ISS, GO:0048538=ISS, GO:0046332=IPI, GO:0009791=IEA, GO:0048701=ISS, GO:0005114=IPI, GO:0007507=ISS, GO:0070022=IC, GO:0018105=IDA, GO:0018107=IDA, GO:0030199=ISS, GO:0007179=IC, GO:0031396=IDA, GO:0043393=IEA, GO:0001701=ISS, GO:0060391=IDA, GO:0060037=ISS, GO:0043235=IDA, GO:0001501=ISS, GO:0043542=IEA, GO:0042060=TAS, GO:0060389=IDA, GO:0005923=IDA, GO:0045893=IDA, GO:0051897=IDA, GO:0008284=IMP, GO:0005886=IDA, GO:0001837=IDA, GO:0009952=ISS, GO:0046872=IEA, GO:0000186=IDA, GO:0019838=IPI, GO:0002088=IEA, GO:0048870=IMP, GO:0005024=IC, GO:0060021=ISS, GO:0007050=TAS, GO:0032331=ISS, GO:0005025=IDA, GO:0030512=TAS, GO:0043066=IMP, GO:0008354=ISS, GO:0050431=IPI, GO:0006355=IDA, GO:0001822=ISS, GO:0043062=TAS, GO:0001824=IEA, GO:0048762=TAS, GO:0010862=IDA, GO:0070411=IPI, GO:0006915=IEA, GO:0042981=IDA, GO:0048663=ISS, GO:0001525=IEA, GO:0006917=IEA, GO:0005524=IDA, GO:0007165=IDA, GO:0060017=ISS, GO:0016020=IEA, GO:0001937=IEA, GO:0004674=IDA, GO:0004675=IDA, GO:0070723=IDA, GO:0006468=IDA, GO:0051272=IMP} activation of MAPKK activity, angiogenesis, anterior/posterior pattern specification, apoptotic process, artery morphogenesis, blastocyst development, cell cycle arrest, cell motility, collagen fibril organization, embryonic cranial skeleton morphogenesis, endothelial cell migration, epithelial to mesenchymal transition, extracellular structure organization, germ cell migration, heart development, in utero embryonic development, induction of apoptosis, kidney development, lens development in camera-type eye, mesenchymal cell differentiation, negative regulation of apoptotic process, negative regulation of chondrocyte differentiation, negative regulation of endothelial cell proliferation, negative regulation of transforming growth factor beta receptor signaling pathway, neuron fate commitment, palate development, parathyroid gland development, pathway-restricted SMAD protein phosphorylation, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, pharyngeal system development, positive regulation of SMAD protein import into nucleus, positive regulation of cell growth, positive regulation of cell proliferation, positive regulation of cellular component movement, positive regulation of filopodium assembly, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of protein kinase B signaling cascade, positive regulation of transcription, DNA-dependent, post-embryonic development, protein phosphorylation, regulation of apoptotic process, regulation of gene expression, regulation of protein binding, regulation of protein ubiquitination, regulation of transcription, DNA-dependent, response to cholesterol, signal transduction, skeletal system development, skeletal system morphogenesis, thymus development, transforming growth factor beta receptor signaling pathway, wound healing membrane, plasma membrane, receptor complex, tight junction, transforming growth factor beta receptor homodimeric complex ATP binding, I-SMAD binding, SMAD binding, growth factor binding, metal ion binding, protein binding, protein serine/threonine kinase activity, transforming growth factor beta binding, transforming growth factor beta receptor activity, type I, transforming growth factor beta-activated receptor activity, transmembrane receptor protein serine/threonine kinase activity, type II transforming growth factor beta receptor binding Human TGFBR2 BHF-UCL UniProtKB {GO:0005515=PMID:7852346, GO:0060044=GO_REF:0000019, GO:0043627=GO_REF:0000019, GO:0051216=GO_REF:0000019, GO:0046332=PMID:18453574, GO:0048701=GO_REF:0000024, GO:0002663=GO_REF:0000024, GO:0007224=GO_REF:0000019, GO:0007507=GO_REF:0000024, GO:0070022=PMID:1326540, GO:0018105=PMID:12015308, GO:0004702=GO_REF:0000002, GO:0018107=PMID:12015308, GO:0042127=GO_REF:0000024, GO:0007179=PMID:1326540, GO:0060434=GO_REF:0000019, GO:0007566=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0031435=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0006898=GO_REF:0000019, GO:0002666=GO_REF:0000024, GO:0007182=GO_REF:0000019, GO:0043235=PMID:8774881, GO:0060443=GO_REF:0000019, GO:0060440=GO_REF:0000019, GO:0007420=GO_REF:0000024, GO:0042060=GO_REF:0000019, GO:0060389=PMID:18453574, GO:2000379=PMID:20160708, GO:0009897=PMID:18453574, GO:0008284=PMID:7761852, GO:0007369=GO_REF:0000019, GO:0005886=Reactome:REACT_160299, GO:0031100=GO_REF:0000019, GO:0005539=PMID:7852346, GO:0046872=GO_REF:0000037, GO:0005829=GO_REF:0000019, GO:0032147=GO_REF:0000024, GO:0051138=GO_REF:0000024, GO:0002088=GO_REF:0000019, GO:0005024=PMID:7852346, GO:0060021=GO_REF:0000024, GO:0043011=GO_REF:0000024, GO:0035162=GO_REF:0000024, GO:0030512=Reactome:REACT_120727, GO:0005026=GO_REF:0000002, GO:0002651=GO_REF:0000024, GO:0050431=PMID:7852346, GO:0001569=GO_REF:0000024, GO:0001568=PMID:10092230, GO:0007584=GO_REF:0000019, GO:0042493=PMID:17878231, GO:0006915=GO_REF:0000019, GO:0048565=GO_REF:0000019, GO:0002053=GO_REF:0000024, GO:0048661=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0009749=GO_REF:0000019, GO:0009612=GO_REF:0000019, GO:0034713=PMID:1333888, GO:0004675=PMID:12015308, GO:0005901=PMID:17878231, GO:0060463=GO_REF:0000019, GO:0070723=PMID:17878231, GO:0043415=GO_REF:0000019, GO:0006468=PMID:12015308, GO:0016021=PMID:7852346, GO:0010634=GO_REF:0000019, GO:0001570=GO_REF:0000024} P37173 TGF-beta receptor type-2 protein 20090115 {GO:0005515=IPI, GO:0060044=IEA, GO:0043627=IEA, GO:0051216=IEA, GO:0046332=IDA, GO:0048701=ISS, GO:0002663=ISS, GO:0007224=IEA, GO:0007507=ISS, GO:0070022=IC, GO:0018105=IDA, GO:0004702=IEA, GO:0018107=IDA, GO:0042127=ISS, GO:0007179=IC, GO:0060434=IEA, GO:0007566=IEA, GO:0007568=IEA, GO:0031435=IEA, GO:0001701=IEA, GO:0006898=IEA, GO:0002666=ISS, GO:0007182=IEA, GO:0043235=IDA, GO:0060443=IEA, GO:0060440=IEA, GO:0007420=ISS, GO:0042060=IEA, GO:0060389=IDA, GO:2000379=IMP, GO:0009897=IDA, GO:0008284=TAS, GO:0007369=IEA, GO:0005886=TAS, GO:0031100=IEA, GO:0005539=IDA, GO:0046872=IEA, GO:0005829=IEA, GO:0032147=ISS, GO:0051138=ISS, GO:0002088=IEA, GO:0005024=IDA, GO:0060021=ISS, GO:0043011=ISS, GO:0035162=ISS, GO:0030512=TAS, GO:0005026=IEA, GO:0002651=ISS, GO:0050431=IDA, GO:0001569=ISS, GO:0001568=TAS, GO:0007584=IEA, GO:0042493=IDA, GO:0006915=IEA, GO:0048565=IEA, GO:0002053=ISS, GO:0048661=IEA, GO:0005524=IEA, GO:0009749=IEA, GO:0009612=IEA, GO:0034713=IPI, GO:0004675=IDA, GO:0005901=IDA, GO:0060463=IEA, GO:0070723=IDA, GO:0043415=IEA, GO:0006468=IDA, GO:0016021=IDA, GO:0010634=IEA, GO:0001570=ISS} activation of protein kinase activity, aging, apoptotic process, blood vessel development, brain development, bronchus morphogenesis, cartilage development, common-partner SMAD protein phosphorylation, digestive tract development, embryo implantation, embryonic cranial skeleton morphogenesis, embryonic hemopoiesis, gastrulation, heart development, in utero embryonic development, lens development in camera-type eye, lung lobe morphogenesis, mammary gland morphogenesis, myeloid dendritic cell differentiation, negative regulation of cardiac muscle cell proliferation, negative regulation of transforming growth factor beta receptor signaling pathway, organ regeneration, palate development, pathway-restricted SMAD protein phosphorylation, patterning of blood vessels, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, positive regulation of B cell tolerance induction, positive regulation of NK T cell differentiation, positive regulation of T cell tolerance induction, positive regulation of cell proliferation, positive regulation of epithelial cell migration, positive regulation of mesenchymal cell proliferation, positive regulation of reactive oxygen species metabolic process, positive regulation of skeletal muscle tissue regeneration, positive regulation of smooth muscle cell proliferation, positive regulation of tolerance induction to self antigen, protein phosphorylation, receptor-mediated endocytosis, regulation of cell proliferation, response to cholesterol, response to drug, response to estrogen stimulus, response to glucose stimulus, response to mechanical stimulus, response to nutrient, smoothened signaling pathway, trachea formation, transforming growth factor beta receptor signaling pathway, vasculogenesis, wound healing caveola, cytosol, external side of plasma membrane, integral to membrane, plasma membrane, receptor complex, transforming growth factor beta receptor homodimeric complex ATP binding, SMAD binding, glycosaminoglycan binding, metal ion binding, mitogen-activated protein kinase kinase kinase binding, protein binding, receptor signaling protein serine/threonine kinase activity, transforming growth factor beta binding, transforming growth factor beta receptor activity, type II, transforming growth factor beta-activated receptor activity, transmembrane receptor protein serine/threonine kinase activity, type I transforming growth factor beta receptor binding Human TGFBR3 BHF-UCL UniProtKB {GO:0005515=PMID:12958365, GO:0055010=GO_REF:0000024, GO:0050680=GO_REF:0000024, GO:0046332=PMID:11157754, GO:0005615=PMID:18184661, GO:0007243=PMID:14557487, GO:0005114=PMID:11157754, GO:0034695=PMID:14557487, GO:0007179=PMID:12958365, GO:0032354=PMID:14557487, GO:0009986=GO_REF:0000024, GO:0017134=GO_REF:0000019, GO:0043393=GO_REF:0000019, GO:0030509=PMID:18184661, GO:0030165=GO_REF:0000024, GO:0005160=PMID:1333192, GO:0060038=GO_REF:0000024, GO:0001889=GO_REF:0000024, GO:0060347=GO_REF:0000024, GO:0007181=GO_REF:0000019, GO:0005887=GO_REF:0000024, GO:0016049=PMID:1333192, GO:0060389=PMID:11157754, GO:0009897=PMID:12958365, GO:0005783=GO_REF:0000019, GO:0031100=GO_REF:0000019, GO:0010719=GO_REF:0000019, GO:0034673=PMID:10746731, GO:0005539=PMID:1333192, GO:0001837=PMID:18184661, GO:0060317=PMID:18184661, GO:0060318=GO_REF:0000024, GO:0006955=PMID:16886151, GO:0051092=GO_REF:0000019, GO:0048185=GO_REF:0000019, GO:0005024=PMID:12958365, GO:0060021=GO_REF:0000024, GO:0008201=PMID:1333192, GO:0030512=GO_REF:0000019, GO:0030511=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0050431=PMID:11157754, GO:0001568=GO_REF:0000019, GO:0001824=GO_REF:0000019, GO:0005578=GO_REF:0000019, GO:0060216=GO_REF:0000024, GO:0015026=PMID:10746731, GO:0070123=PMID:11157754, GO:0034699=PMID:14557487, GO:0003007=GO_REF:0000024, GO:0016477=GO_REF:0000024, GO:0051271=PMID:17999987, GO:0010633=GO_REF:0000019} Q03167 Transforming growth factor beta receptor type 3 protein 20080820 {GO:0005515=IPI, GO:0055010=ISS, GO:0050680=ISS, GO:0046332=IMP, GO:0005615=TAS, GO:0007243=IMP, GO:0005114=IDA, GO:0034695=IDA, GO:0007179=IDA, GO:0032354=IDA, GO:0009986=ISS, GO:0017134=IEA, GO:0043393=IEA, GO:0030509=IDA, GO:0030165=ISS, GO:0005160=ISS, GO:0060038=ISS, GO:0001889=ISS, GO:0060347=ISS, GO:0007181=IEA, GO:0005887=ISS, GO:0016049=ISS, GO:0060389=IMP, GO:0009897=IDA, GO:0005783=IEA, GO:0031100=IEA, GO:0010719=IEA, GO:0034673=IDA, GO:0005539=TAS, GO:0001837=IDA, GO:0060317=IDA, GO:0060318=ISS, GO:0006955=IMP, GO:0051092=IEA, GO:0048185=IEA, GO:0005024=IDA, GO:0060021=ISS, GO:0008201=ISS, GO:0030512=IEA, GO:0030511=IEA, GO:0001666=IEA, GO:0050431=IDA, GO:0001568=IEA, GO:0001824=IEA, GO:0005578=IEA, GO:0060216=ISS, GO:0015026=IDA, GO:0070123=IDA, GO:0034699=IDA, GO:0003007=ISS, GO:0016477=ISS, GO:0051271=IDA, GO:0010633=IEA} BMP signaling pathway, blastocyst development, blood vessel development, cardiac epithelial to mesenchymal transition, cardiac muscle cell proliferation, cell growth, cell migration, definitive erythrocyte differentiation, definitive hemopoiesis, epithelial to mesenchymal transition, heart morphogenesis, heart trabecula formation, immune response, intracellular protein kinase cascade, liver development, negative regulation of cellular component movement, negative regulation of epithelial cell migration, negative regulation of epithelial cell proliferation, negative regulation of epithelial to mesenchymal transition, negative regulation of transforming growth factor beta receptor signaling pathway, organ regeneration, palate development, pathway-restricted SMAD protein phosphorylation, positive regulation of NF-kappaB transcription factor activity, positive regulation of transforming growth factor beta receptor signaling pathway, regulation of protein binding, response to follicle-stimulating hormone stimulus, response to hypoxia, response to luteinizing hormone stimulus, response to prostaglandin E stimulus, transforming growth factor beta receptor complex assembly, transforming growth factor beta receptor signaling pathway, ventricular cardiac muscle tissue morphogenesis cell surface, endoplasmic reticulum, external side of plasma membrane, extracellular space, inhibin-betaglycan-ActRII complex, integral to plasma membrane, proteinaceous extracellular matrix PDZ domain binding, SMAD binding, activin binding, coreceptor activity, fibroblast growth factor binding, glycosaminoglycan binding, heparin binding, protein binding, transforming growth factor beta binding, transforming growth factor beta receptor activity, type III, transforming growth factor beta receptor binding, transforming growth factor beta-activated receptor activity, type II transforming growth factor beta receptor binding Human UniProtKB:P32121 TGFBRAP1 UniProtKB UniProtKB {GO:0005515=PMID:11278302, GO:0007165=PMID:11278302, GO:0006355=PMID:11278302, GO:0005737=GO_REF:0000039, GO:0005083=GO_REF:0000002, GO:0016020=PMID:11278302, GO:0007179=PMID:9545258, GO:0046332=PMID:11278302, GO:0016192=GO_REF:0000002, GO:0005160=PMID:11278302, GO:0006886=GO_REF:0000002} Q8WUH2 Transforming growth factor-beta receptor-associated protein 1 protein 20090115 {GO:0005515=IPI, GO:0007165=IDA, GO:0006355=IDA, GO:0005737=IEA, GO:0005083=IEA, GO:0016020=IDA, GO:0007179=TAS, GO:0046332=IDA, GO:0016192=IEA, GO:0005160=IDA, GO:0006886=IEA} intracellular protein transport, regulation of transcription, DNA-dependent, signal transduction, transforming growth factor beta receptor signaling pathway, vesicle-mediated transport cytoplasm, membrane SMAD binding, protein binding, small GTPase regulator activity, transforming growth factor beta receptor binding Human TGIF1 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0007368=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0006367=Reactome:REACT_12627, GO:0060041=GO_REF:0000019, GO:0005634=GO_REF:0000038, GO:0009953=GO_REF:0000019, GO:0048146=GO_REF:0000019, GO:0010470=GO_REF:0000019, GO:0007179=Reactome:REACT_6844, GO:0042493=GO_REF:0000019, GO:0003714=PMID:10764806, GO:0070410=GO_REF:0000019, GO:0001843=GO_REF:0000019, GO:0007275=PMID:8537382, GO:0000122=Reactome:REACT_121111, GO:0006351=Reactome:REACT_121061, GO:0043565=GO_REF:0000002, GO:0071363=GO_REF:0000019, GO:0045666=GO_REF:0000019, GO:0048387=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0038092=GO_REF:0000019, GO:0005654=Reactome:REACT_121142} Q15583 Homeobox protein TGIF1 protein 20130301 {GO:0010467=TAS, GO:0007368=IEA, GO:0008285=IEA, GO:0003700=IEA, GO:0006367=TAS, GO:0060041=IEA, GO:0005634=IEA, GO:0009953=IEA, GO:0048146=IEA, GO:0010470=IEA, GO:0007179=TAS, GO:0042493=IEA, GO:0003714=TAS, GO:0070410=IEA, GO:0001843=IEA, GO:0007275=TAS, GO:0000122=TAS, GO:0006351=TAS, GO:0043565=IEA, GO:0071363=IEA, GO:0045666=IEA, GO:0048387=IEA, GO:0003682=IEA, GO:0038092=IEA, GO:0005654=TAS} cellular response to growth factor stimulus, determination of left/right symmetry, dorsal/ventral pattern formation, gene expression, multicellular organismal development, negative regulation of cell proliferation, negative regulation of retinoic acid receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, neural tube closure, nodal signaling pathway, positive regulation of fibroblast proliferation, positive regulation of neuron differentiation, regulation of gastrulation, response to drug, retina development in camera-type eye, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway nucleoplasm, nucleus chromatin binding, co-SMAD binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human TGIF2 BHF-UCL UniProtKB {GO:0043565=GO_REF:0000002, GO:0010467=Reactome:REACT_71, GO:0006355=PMID:11006116, GO:0006367=Reactome:REACT_12627, GO:0003700=PMID:11006116, GO:0007179=Reactome:REACT_6844, GO:0005654=Reactome:REACT_121142, GO:0005634=PMID:11006116, GO:0000122=PMID:22783022, GO:0006351=Reactome:REACT_121061} Q9GZN2 Homeobox protein TGIF2 protein 20121121 {GO:0043565=IEA, GO:0010467=TAS, GO:0006355=NAS, GO:0006367=TAS, GO:0003700=NAS, GO:0007179=TAS, GO:0005654=TAS, GO:0005634=TAS, GO:0000122=IMP, GO:0006351=TAS} gene expression, negative regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway nucleoplasm, nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human TGIF2LY UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q8IUE0 Homeobox protein TGIF2LY protein 20130413 {GO:0043565=IEA, GO:0003700=IEA, GO:0005634=IEA, GO:0006351=IEA} transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0191 TGM1 UniProtKB UniProtKB {GO:0005515=PMID:10510474, GO:0005913=GO_REF:0000019, GO:0018149=GO_REF:0000002, GO:0030216=PMID:8824274, GO:0003810=PMID:7961731, GO:0031424=GO_REF:0000037, GO:0009887=GO_REF:0000019, GO:0031224=PMID:8824274, GO:0043163=PMID:14645372, GO:0001533=PMID:8824274, GO:0006464=PMID:1979171, GO:0046872=GO_REF:0000037} P22735 Protein-glutamine gamma-glutamyltransferase K protein 20060124 {GO:0005515=IPI, GO:0005913=IEA, GO:0018149=IEA, GO:0030216=IDA, GO:0003810=IDA, GO:0031424=IEA, GO:0009887=IEA, GO:0031224=IDA, GO:0043163=TAS, GO:0001533=TAS, GO:0006464=NAS, GO:0046872=IEA} cell envelope organization, cellular protein modification process, keratinization, keratinocyte differentiation, organ morphogenesis, peptide cross-linking cell-cell adherens junction, cornified envelope, intrinsic to membrane metal ion binding, protein binding, protein-glutamine gamma-glutamyltransferase activity Human TGM2 IntAct UniProtKB {GO:0005515=PMID:22442151, GO:0005886=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0043277=PMID:19628791, GO:0006917=GO_REF:0000019, GO:0005525=GO_REF:0000019, GO:0048661=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0045785=GO_REF:0000024, GO:0005739=GO_REF:0000019, GO:0018149=GO_REF:0000002, GO:0001974=GO_REF:0000019, GO:0051482=GO_REF:0000019, GO:0003810=GO_REF:0000024, GO:0050729=GO_REF:0000019, GO:0018153=GO_REF:0000019, GO:0051260=GO_REF:0000019, GO:0060662=GO_REF:0000019, GO:0043123=GO_REF:0000019, GO:0060445=GO_REF:0000019} P21980 Protein-glutamine gamma-glutamyltransferase 2 protein 20130415 {GO:0005515=IPI, GO:0005886=IEA, GO:0019904=IEA, GO:0043277=IDA, GO:0006917=IEA, GO:0005525=IEA, GO:0048661=IEA, GO:0046872=IEA, GO:0045785=ISS, GO:0005739=IEA, GO:0018149=IEA, GO:0001974=IEA, GO:0051482=IEA, GO:0003810=ISS, GO:0050729=IEA, GO:0018153=IEA, GO:0051260=IEA, GO:0060662=IEA, GO:0043123=IEA, GO:0060445=IEA} apoptotic cell clearance, blood vessel remodeling, branching involved in salivary gland morphogenesis, elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway, induction of apoptosis, isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine, peptide cross-linking, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of cell adhesion, positive regulation of inflammatory response, positive regulation of smooth muscle cell proliferation, protein homooligomerization, salivary gland cavitation mitochondrion, plasma membrane GTP binding, metal ion binding, protein binding, protein domain specific binding, protein-glutamine gamma-glutamyltransferase activity Human UniProtKB:P02751 TGM3 GOC UniProtKB {GO:0016746=PMID:15193648, GO:0051262=PMID:5038456, GO:0000287=PMID:14645372, GO:0005509=PMID:14645372, GO:0031424=GO_REF:0000037, GO:0003924=PMID:14645372, GO:0003824=PMID:8099584, GO:0005525=PMID:14645372, GO:0031234=PMID:5038456, GO:0031069=PMID:15193648, GO:0006184=PMID:14645372, GO:0005737=PMID:12850301, GO:0018149=PMID:24643, GO:0030216=PMID:24643, GO:0003810=PMID:8099584, GO:0019003=PMID:14645372, GO:0043163=PMID:24643, GO:0006464=PMID:8099584} Q08188 Protein-glutamine gamma-glutamyltransferase E protein 20130413 {GO:0016746=TAS, GO:0051262=IDA, GO:0000287=IDA, GO:0005509=IDA, GO:0031424=IEA, GO:0003924=IDA, GO:0003824=IDA, GO:0005525=IDA, GO:0031234=IDA, GO:0031069=TAS, GO:0006184=IDA, GO:0005737=IDA, GO:0018149=IDA, GO:0030216=TAS, GO:0003810=IDA, GO:0019003=IDA, GO:0043163=IDA, GO:0006464=NAS} GTP catabolic process, cell envelope organization, cellular protein modification process, hair follicle morphogenesis, keratinization, keratinocyte differentiation, peptide cross-linking, protein tetramerization cytoplasm, extrinsic to internal side of plasma membrane GDP binding, GTP binding, GTPase activity, calcium ion binding, catalytic activity, magnesium ion binding, protein-glutamine gamma-glutamyltransferase activity, transferase activity, transferring acyl groups Human TGM4 UniProtKB UniProtKB {GO:0018184=GO_REF:0000029, GO:0018149=GO_REF:0000029, GO:0003810=PMID:7916568, GO:0005575=GO_REF:0000015, GO:0046872=GO_REF:0000037} P49221 Protein-glutamine gamma-glutamyltransferase 4 protein 20061026 {GO:0018184=NAS, GO:0018149=NAS, GO:0003810=NAS, GO:0005575=ND, GO:0046872=IEA} peptide cross-linking, protein polyamination cellular_component metal ion binding, protein-glutamine gamma-glutamyltransferase activity Human TGM5 PINC UniProtKB {GO:0005737=GO_REF:0000039, GO:0018149=GO_REF:0000002, GO:0008544=PMID:9452468, GO:0003810=GO_REF:0000003, GO:0006464=PMID:9452468, GO:0046872=GO_REF:0000037} O43548 Protein-glutamine gamma-glutamyltransferase 5 protein 20030904 {GO:0005737=IEA, GO:0018149=IEA, GO:0008544=TAS, GO:0003810=IEA, GO:0006464=TAS, GO:0046872=IEA} cellular protein modification process, epidermis development, peptide cross-linking cytoplasm metal ion binding, protein-glutamine gamma-glutamyltransferase activity Human TGOLN2 HPA UniProtKB {GO:0005515=PMID:17474147, GO:0030133=PMID:9422759, GO:0005802=GO_REF:0000002, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0016021=GO_REF:0000037} O43493 Trans-Golgi network integral membrane protein 2 protein 20101115 {GO:0005515=IPI, GO:0030133=TAS, GO:0005802=IEA, GO:0005794=IDA, GO:0005886=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0016021=IEA} Golgi apparatus, integral to membrane, nucleolus, nucleus, plasma membrane, trans-Golgi network, transport vesicle protein binding Human TGS1 HPA UniProtKB {GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000037, GO:0015030=GO_REF:0000039, GO:0016070=Reactome:REACT_21257, GO:0005634=GO_REF:0000052, GO:0036261=PMID:16687569, GO:0044281=Reactome:REACT_111217, GO:0034660=Reactome:REACT_11052, GO:0000387=Reactome:REACT_11066, GO:0006351=GO_REF:0000037, GO:0005829=Reactome:REACT_10002, GO:0001510=PMID:16687569, GO:0005737=GO_REF:0000052, GO:0071164=PMID:16687569, GO:0030532=PMID:16687569, GO:0022613=PMID:16687569, GO:0005654=Reactome:REACT_19175, GO:0009452=GO_REF:0000002, GO:0071167=PMID:16687569, GO:0044255=Reactome:REACT_22279} Q96RS0 Trimethylguanosine synthase protein 20100326 {GO:0010467=TAS, GO:0006355=IEA, GO:0015030=IEA, GO:0016070=TAS, GO:0005634=IDA, GO:0036261=IDA, GO:0044281=TAS, GO:0034660=TAS, GO:0000387=TAS, GO:0006351=IEA, GO:0005829=TAS, GO:0001510=IDA, GO:0005737=IDA, GO:0071164=IDA, GO:0030532=IC, GO:0022613=IC, GO:0005654=TAS, GO:0009452=IEA, GO:0071167=IC, GO:0044255=TAS} 7-methylguanosine RNA capping, 7-methylguanosine cap hypermethylation, RNA metabolic process, RNA methylation, cellular lipid metabolic process, gene expression, ncRNA metabolic process, regulation of transcription, DNA-dependent, ribonucleoprotein complex biogenesis, ribonucleoprotein complex import into nucleus, small molecule metabolic process, spliceosomal snRNP assembly, transcription, DNA-dependent Cajal body, cytoplasm, cytosol, nucleoplasm, nucleus, small nuclear ribonucleoprotein complex RNA trimethylguanosine synthase activity Human TH InterPro UniProtKB {GO:0005515=PMID:11943812, GO:0033162=PMID:12631248, GO:0009651=GO_REF:0000019, GO:0046684=GO_REF:0000019, GO:0018963=GO_REF:0000019, GO:0007605=GO_REF:0000019, GO:0008016=GO_REF:0000024, GO:0009653=PMID:7715703, GO:0010043=GO_REF:0000019, GO:0048596=GO_REF:0000024, GO:0007507=GO_REF:0000024, GO:0034641=Reactome:REACT_13, GO:0042745=GO_REF:0000019, GO:0051602=GO_REF:0000019, GO:0009414=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0009887=GO_REF:0000024, GO:0031667=GO_REF:0000019, GO:0007613=GO_REF:0000024, GO:0009416=GO_REF:0000019, GO:0007612=GO_REF:0000024, GO:0016714=GO_REF:0000002, GO:0032355=GO_REF:0000019, GO:0033076=GO_REF:0000019, GO:0051412=GO_REF:0000019, GO:0005506=GO_REF:0000002, GO:0007617=GO_REF:0000019, GO:0071287=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0009072=GO_REF:0000002, GO:0035240=GO_REF:0000019, GO:0009635=GO_REF:0000019, GO:0042214=GO_REF:0000019, GO:0071316=GO_REF:0000019, GO:0005790=PMID:12457228, GO:0006585=PMID:10907721, GO:0035176=GO_REF:0000019, GO:0009898=PMID:12457228, GO:0042462=GO_REF:0000024, GO:0016597=GO_REF:0000019, GO:0015842=GO_REF:0000019, GO:0043005=PMID:17135716, GO:0045472=GO_REF:0000019, GO:0021987=GO_REF:0000019, GO:0045471=PMID:18343820, GO:0043434=GO_REF:0000019, GO:0005634=GO_REF:0000024, GO:0010259=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0030425=GO_REF:0000019, GO:0005829=Reactome:REACT_15366, GO:0042416=PMID:12457228, GO:0005739=GO_REF:0000019, GO:0042418=PMID:12457228, GO:0005737=PMID:10907721, GO:0043195=GO_REF:0000019, GO:0001963=GO_REF:0000024, GO:0006631=GO_REF:0000019, GO:0043204=GO_REF:0000024, GO:0007626=GO_REF:0000024, GO:0016137=GO_REF:0000019, GO:0071333=GO_REF:0000019, GO:0006665=GO_REF:0000019, GO:0001666=PMID:17520326, GO:0014823=GO_REF:0000019, GO:0031410=PMID:12457228, GO:0035690=GO_REF:0000019, GO:0008198=GO_REF:0000019, GO:0008199=GO_REF:0000019, GO:0008021=GO_REF:0000019, GO:0003007=PMID:12113410, GO:0001975=GO_REF:0000019, GO:0004511=GO_REF:0000002, GO:0071363=GO_REF:0000019, GO:0019825=GO_REF:0000019, GO:0052314=GO_REF:0000019, GO:0034617=GO_REF:0000019, GO:0043473=PMID:12631248, GO:0042421=PMID:12457228, GO:0042755=GO_REF:0000019, GO:0042136=GO_REF:0000037, GO:0007601=GO_REF:0000024, GO:0042423=Reactome:REACT_15551} Q0PWM2 Tyrosine 3-monooxygenase protein 20130413 {GO:0005515=IPI, GO:0033162=IDA, GO:0009651=IEA, GO:0046684=IEA, GO:0018963=IEA, GO:0007605=IEA, GO:0008016=ISS, GO:0009653=TAS, GO:0010043=IEA, GO:0048596=ISS, GO:0007507=ISS, GO:0034641=TAS, GO:0042745=IEA, GO:0051602=IEA, GO:0009414=IEA, GO:0032496=IEA, GO:0009887=ISS, GO:0031667=IEA, GO:0007613=ISS, GO:0009416=IEA, GO:0007612=ISS, GO:0016714=IEA, GO:0032355=IEA, GO:0033076=IEA, GO:0051412=IEA, GO:0005506=IEA, GO:0007617=IEA, GO:0071287=IEA, GO:0019904=IEA, GO:0009072=IEA, GO:0035240=IEA, GO:0009635=IEA, GO:0042214=IEA, GO:0071316=IEA, GO:0005790=IDA, GO:0006585=NAS, GO:0035176=IEA, GO:0009898=IDA, GO:0042462=ISS, GO:0016597=IEA, GO:0015842=IEA, GO:0043005=IDA, GO:0045472=IEA, GO:0021987=IEA, GO:0045471=IDA, GO:0043434=IEA, GO:0005634=ISS, GO:0010259=IEA, GO:0044281=TAS, GO:0030425=IEA, GO:0005829=TAS, GO:0042416=IDA, GO:0005739=IEA, GO:0042418=IDA, GO:0005737=IDA, GO:0043195=IEA, GO:0001963=ISS, GO:0006631=IEA, GO:0043204=ISS, GO:0007626=ISS, GO:0016137=IEA, GO:0071333=IEA, GO:0006665=IEA, GO:0001666=IDA, GO:0014823=IEA, GO:0031410=IDA, GO:0035690=IEA, GO:0008198=IEA, GO:0008199=IEA, GO:0008021=IEA, GO:0003007=NAS, GO:0001975=IEA, GO:0004511=IEA, GO:0071363=IEA, GO:0019825=IEA, GO:0052314=IEA, GO:0034617=IEA, GO:0043473=TAS, GO:0042421=IDA, GO:0042755=IEA, GO:0042136=IEA, GO:0007601=ISS, GO:0042423=TAS} anatomical structure morphogenesis, aromatic amino acid family metabolic process, catecholamine biosynthetic process, cellular nitrogen compound metabolic process, cellular response to drug, cellular response to glucose stimulus, cellular response to growth factor stimulus, cellular response to manganese ion, cellular response to nicotine, cerebral cortex development, circadian sleep/wake cycle, dopamine biosynthetic process, dopamine biosynthetic process from tyrosine, eating behavior, embryonic camera-type eye morphogenesis, epinephrine biosynthetic process, eye photoreceptor cell development, fatty acid metabolic process, glycoside metabolic process, heart development, heart morphogenesis, isoquinoline alkaloid metabolic process, learning, locomotory behavior, mating behavior, memory, multicellular organismal aging, neurotransmitter biosynthetic process, norepinephrine biosynthetic process, organ morphogenesis, phthalate metabolic process, phytoalexin metabolic process, pigmentation, regulation of heart contraction, response to activity, response to amphetamine, response to corticosterone stimulus, response to electrical stimulus, response to estradiol stimulus, response to ethanol, response to ether, response to herbicide, response to hypoxia, response to light stimulus, response to lipopolysaccharide, response to nutrient levels, response to peptide hormone stimulus, response to pyrethroid, response to salt stress, response to water deprivation, response to zinc ion, sensory perception of sound, small molecule metabolic process, social behavior, sphingolipid metabolic process, synaptic transmission, dopaminergic, synaptic vesicle amine transport, terpene metabolic process, visual perception cytoplasm, cytoplasmic vesicle, cytosol, dendrite, internal side of plasma membrane, melanosome membrane, mitochondrion, neuron projection, nucleus, perikaryon, smooth endoplasmic reticulum, synaptic vesicle, terminal bouton amino acid binding, dopamine binding, ferric iron binding, ferrous iron binding, iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen, oxygen binding, protein binding, protein domain specific binding, tetrahydrobiopterin binding, tyrosine 3-monooxygenase activity Human InterPro:IPR001273 THADA null null {} null null null null {} null null null THAP1 UniProtKB UniProtKB {GO:0005515=PMID:20200153, GO:0043565=PMID:20010837, GO:0007346=PMID:17003378, GO:0006355=PMID:17003378, GO:0007049=GO_REF:0000037, GO:0016605=GO_REF:0000039, GO:0001935=PMID:17003378, GO:0008270=PMID:15863623, GO:0005634=PMID:17003378, GO:0003676=GO_REF:0000002, GO:0006351=PMID:17003378} Q9NVV9 THAP domain-containing protein 1 protein 20120708 {GO:0005515=IPI, GO:0043565=IDA, GO:0007346=IMP, GO:0006355=IMP, GO:0007049=IEA, GO:0016605=IEA, GO:0001935=IMP, GO:0008270=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0006351=IMP} cell cycle, endothelial cell proliferation, regulation of mitotic cell cycle, regulation of transcription, DNA-dependent, transcription, DNA-dependent PML body, nucleus nucleic acid binding, protein binding, sequence-specific DNA binding, zinc ion binding Human UniProtKB:O15294 THAP10 UniProtKB UniProtKB {GO:0003677=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q9P2Z0 THAP domain-containing protein 10 protein 20130413 {GO:0003677=IEA, GO:0046872=IEA} DNA binding, metal ion binding Human UniProtKB-KW:KW-0479 THAP11 HPA UniProtKB {GO:0005515=PMID:21988832, GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0005825=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96EK4 THAP domain-containing protein 11 protein 20120912 {GO:0005515=IPI, GO:0005737=IDA, GO:0006355=IEA, GO:0005825=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0046872=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, half bridge of spindle pole body, nucleolus, nucleus DNA binding, metal ion binding, protein binding Human THAP2 LIFEdb UniProtKB {GO:0005730=GO_REF:0000054, GO:0003677=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q9H0W7 THAP domain-containing protein 2 protein 20100607 {GO:0005730=IDA, GO:0003677=IEA, GO:0046872=IEA} nucleolus DNA binding, metal ion binding Human THAP3 UniProtKB UniProtKB {GO:0005515=PMID:20200153, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q8WTV1 THAP domain-containing protein 3 protein 20120708 {GO:0005515=IPI, GO:0003676=IEA, GO:0003677=IEA, GO:0046872=IEA} DNA binding, metal ion binding, nucleic acid binding, protein binding Human UniProtKB:O15294 THAP4 UniProtKB UniProtKB {GO:0003677=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q8WY91 THAP domain-containing protein 4 protein 20130413 {GO:0003677=IEA, GO:0046872=IEA} DNA binding, metal ion binding Human UniProtKB-KW:KW-0479 THAP5 UniProtKB UniProtKB {GO:0007049=GO_REF:0000037, GO:0005634=PMID:19502560, GO:0002020=PMID:19502560, GO:0045786=PMID:19502560, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q7Z6K1 THAP domain-containing protein 5 protein 20091126 {GO:0007049=IEA, GO:0005634=IDA, GO:0002020=IPI, GO:0045786=IMP, GO:0003676=IEA, GO:0003677=IEA, GO:0046872=IEA} cell cycle, negative regulation of cell cycle nucleus DNA binding, metal ion binding, nucleic acid binding, protease binding Human UniProtKB:O43464 THAP6 LIFEdb UniProtKB {GO:0015630=GO_REF:0000054, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q8TBB0 THAP domain-containing protein 6 protein 20100607 {GO:0015630=IDA, GO:0003676=IEA, GO:0003677=IEA, GO:0046872=IEA} microtubule cytoskeleton DNA binding, metal ion binding, nucleic acid binding Human THAP7 UniProtKB UniProtKB {GO:0047485=PMID:17577209, GO:0016607=PMID:17577209, GO:0005694=GO_REF:0000039, GO:0070742=PMID:17577209, GO:0045892=PMID:17577209, GO:0003677=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9BT49 THAP domain-containing protein 7 protein 20090723 {GO:0047485=IPI, GO:0016607=IDA, GO:0005694=IEA, GO:0070742=IDA, GO:0045892=IDA, GO:0003677=IEA, GO:0046872=IEA, GO:0006351=IEA} negative regulation of transcription, DNA-dependent, transcription, DNA-dependent chromosome, nuclear speck C2H2 zinc finger domain binding, DNA binding, metal ion binding, protein N-terminus binding Human THAP8 UniProtKB UniProtKB {GO:0003677=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q8NA92 THAP domain-containing protein 8 protein 20130413 {GO:0003677=IEA, GO:0046872=IEA} DNA binding, metal ion binding Human UniProtKB-KW:KW-0479 THBD BHF-UCL UniProtKB {GO:0010544=PMID:17379830, GO:0005515=PMID:17379830, GO:0007565=GO_REF:0000019, GO:0009986=PMID:17379830, GO:0005886=Reactome:REACT_1834, GO:0005509=GO_REF:0000002, GO:0051918=PMID:17379830, GO:0009790=GO_REF:0000019, GO:0050900=Reactome:REACT_12051, GO:0005887=PMID:2822087, GO:0007596=Reactome:REACT_2051, GO:0030195=PMID:17379830, GO:0030246=GO_REF:0000002, GO:0004872=PMID:2822087, GO:0004888=GO_REF:0000002} P07204 Thrombomodulin protein 20100426 {GO:0010544=TAS, GO:0005515=IPI, GO:0007565=IEA, GO:0009986=IDA, GO:0005886=TAS, GO:0005509=IEA, GO:0051918=TAS, GO:0009790=IEA, GO:0050900=TAS, GO:0005887=TAS, GO:0007596=TAS, GO:0030195=TAS, GO:0030246=IEA, GO:0004872=TAS, GO:0004888=IEA} blood coagulation, embryo development, female pregnancy, leukocyte migration, negative regulation of blood coagulation, negative regulation of fibrinolysis, negative regulation of platelet activation cell surface, integral to plasma membrane, plasma membrane calcium ion binding, carbohydrate binding, protein binding, receptor activity, transmembrane signaling receptor activity Human THBS1 BHF-UCL UniProtKB {GO:0005515=PMID:15700281, GO:0003417=GO_REF:0000019, GO:0043499=PMID:6777381, GO:0043032=PMID:18757424, GO:0005615=PMID:6777381, GO:0032914=GO_REF:0000024, GO:0042802=PMID:9304800, GO:0034605=PMID:9304800, GO:0010763=PMID:18555217, GO:0001948=PMID:6438154, GO:0032026=PMID:6777381, GO:0030335=PMID:17413041, GO:0017134=PMID:17996481, GO:2000462=PMID:2435757, GO:0005509=PMID:9304800, GO:0042535=PMID:18726995, GO:0050840=GO_REF:0000019, GO:0030169=PMID:6693501, GO:0043394=PMID:9304800, GO:0010748=PMID:17416590, GO:0030168=Reactome:REACT_798, GO:0010751=PMID:17416590, GO:0010595=PMID:18555217, GO:0043536=PMID:18555217, GO:0051592=PMID:6777381, GO:0010596=PMID:18555217, GO:0005178=PMID:17413041, GO:0010754=PMID:17416590, GO:0043236=PMID:6693501, GO:0010759=GO_REF:0000024, GO:0032570=PMID:9304800, GO:0001786=PMID:18940719, GO:0010757=PMID:6438154, GO:0070051=PMID:6693501, GO:2000379=PMID:18757424, GO:0043537=PMID:18555217, GO:0070052=PMID:6693501, GO:0009897=PMID:6777381, GO:0001953=PMID:17416590, GO:0051897=PMID:18653767, GO:0010811=GO_REF:0000019, GO:0048514=GO_REF:0000019, GO:0002040=PMID:17879962, GO:0051895=PMID:9304800, GO:0000187=PMID:17413041, GO:0006955=PMID:18674744, GO:0006954=GO_REF:0000019, GO:0050921=PMID:18555217, GO:0031091=PMID:6777381, GO:0007050=PMID:17596205, GO:0031093=Reactome:REACT_21351, GO:0043154=PMID:18653767, GO:0007155=PMID:9304800, GO:0030141=PMID:101549, GO:0001968=PMID:6693501, GO:0008201=PMID:101549, GO:0030511=PMID:18555217, GO:0001666=PMID:9304800, GO:0050431=GO_REF:0000024, GO:0043066=PMID:17879962, GO:0002605=PMID:16882710, GO:0003197=GO_REF:0000019, GO:0042493=PMID:19738618, GO:0051918=PMID:6438154, GO:0005577=PMID:3997886, GO:0005576=Reactome:REACT_21351, GO:0045727=PMID:15700281, GO:0002544=PMID:18674744, GO:0006917=PMID:18726995, GO:0043652=PMID:16882710, GO:0002581=PMID:16882710, GO:0003151=GO_REF:0000019, GO:0045766=PMID:17413041, GO:0009749=PMID:18096704, GO:0031012=PMID:22261194, GO:0018149=PMID:3997886, GO:0016477=PMID:18555217, GO:0032695=PMID:16882710, GO:0001937=PMID:17996481, GO:0007596=Reactome:REACT_604, GO:0030194=PMID:3997886, GO:0040037=PMID:17996481, GO:0002576=Reactome:REACT_318, GO:0016525=PMID:17996481, GO:0042327=PMID:17413041} P07996 Thrombospondin-1 protein 20120228 {GO:0005515=IPI, GO:0003417=IEA, GO:0043499=IDA, GO:0043032=IDA, GO:0005615=IDA, GO:0032914=ISS, GO:0042802=NAS, GO:0034605=NAS, GO:0010763=IDA, GO:0001948=NAS, GO:0032026=IDA, GO:0030335=IMP, GO:0017134=IDA, GO:2000462=IDA, GO:0005509=NAS, GO:0042535=IDA, GO:0050840=IEA, GO:0030169=IDA, GO:0043394=TAS, GO:0010748=IDA, GO:0030168=TAS, GO:0010751=IDA, GO:0010595=IDA, GO:0043536=IDA, GO:0051592=IDA, GO:0010596=IDA, GO:0005178=IMP, GO:0010754=IDA, GO:0043236=IDA, GO:0010759=ISS, GO:0032570=TAS, GO:0001786=IDA, GO:0010757=IDA, GO:0070051=IDA, GO:2000379=IDA, GO:0043537=IDA, GO:0070052=IDA, GO:0009897=IDA, GO:0001953=IDA, GO:0051897=IDA, GO:0010811=IEA, GO:0048514=IEA, GO:0002040=IMP, GO:0051895=TAS, GO:0000187=IMP, GO:0006955=IEP, GO:0006954=IEA, GO:0050921=IDA, GO:0031091=IDA, GO:0007050=IDA, GO:0031093=TAS, GO:0043154=IDA, GO:0007155=NAS, GO:0030141=IDA, GO:0001968=IDA, GO:0008201=IDA, GO:0030511=IDA, GO:0001666=NAS, GO:0050431=ISS, GO:0043066=TAS, GO:0002605=IDA, GO:0003197=IEA, GO:0042493=IEP, GO:0051918=IDA, GO:0005577=IDA, GO:0005576=TAS, GO:0045727=IDA, GO:0002544=IEP, GO:0006917=IDA, GO:0043652=IDA, GO:0002581=IDA, GO:0003151=IEA, GO:0045766=IMP, GO:0009749=IDA, GO:0031012=ISS, GO:0018149=IDA, GO:0016477=IDA, GO:0032695=IDA, GO:0001937=IDA, GO:0007596=TAS, GO:0030194=IDA, GO:0040037=IDA, GO:0002576=TAS, GO:0016525=IDA, GO:0042327=IMP} activation of MAPK activity, blood coagulation, blood vessel morphogenesis, cell adhesion, cell cycle arrest, cell migration, cellular response to heat, chronic inflammatory response, endocardial cushion development, engulfment of apoptotic cell, growth plate cartilage development, immune response, induction of apoptosis, inflammatory response, negative regulation of angiogenesis, negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II, negative regulation of apoptotic process, negative regulation of blood vessel endothelial cell migration, negative regulation of cGMP-mediated signaling, negative regulation of cell-matrix adhesion, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of dendritic cell antigen processing and presentation, negative regulation of endothelial cell migration, negative regulation of endothelial cell proliferation, negative regulation of fibrinolysis, negative regulation of fibroblast growth factor receptor signaling pathway, negative regulation of focal adhesion assembly, negative regulation of interleukin-12 production, negative regulation of nitric oxide mediated signal transduction, negative regulation of plasma membrane long-chain fatty acid transport, negative regulation of plasminogen activation, outflow tract morphogenesis, peptide cross-linking, platelet activation, platelet degranulation, positive regulation of angiogenesis, positive regulation of blood coagulation, positive regulation of blood vessel endothelial cell migration, positive regulation of cell migration, positive regulation of cell-substrate adhesion, positive regulation of chemotaxis, positive regulation of endothelial cell migration, positive regulation of eukaryotic cell surface binding, positive regulation of fibroblast migration, positive regulation of macrophage activation, positive regulation of macrophage chemotaxis, positive regulation of phosphorylation, positive regulation of protein kinase B signaling cascade, positive regulation of reactive oxygen species metabolic process, positive regulation of transforming growth factor beta receptor signaling pathway, positive regulation of transforming growth factor beta1 production, positive regulation of translation, positive regulation of tumor necrosis factor biosynthetic process, response to calcium ion, response to drug, response to glucose stimulus, response to hypoxia, response to magnesium ion, response to progesterone stimulus, sprouting angiogenesis external side of plasma membrane, extracellular matrix, extracellular region, extracellular space, fibrinogen complex, platelet alpha granule, platelet alpha granule lumen, secretory granule calcium ion binding, collagen V binding, eukaryotic cell surface binding, extracellular matrix binding, fibrinogen binding, fibroblast growth factor binding, fibronectin binding, glycoprotein binding, heparin binding, identical protein binding, integrin binding, laminin binding, low-density lipoprotein particle binding, phosphatidylserine binding, protein binding, proteoglycan binding, transforming growth factor beta binding colocalizes_with Human UniProtKB:F1SS26 THBS2 ENSEMBL UniProtKB {GO:0005515=PMID:19818485, GO:0016525=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0005576=Reactome:REACT_16880, GO:0007155=GO_REF:0000037, GO:0008201=GO_REF:0000037, GO:0005604=GO_REF:0000019} Q5RI53 Thrombospondin-2 protein 20130413 {GO:0005515=IPI, GO:0016525=IEA, GO:0005509=IEA, GO:0005576=TAS, GO:0007155=IEA, GO:0008201=IEA, GO:0005604=IEA} cell adhesion, negative regulation of angiogenesis basement membrane, extracellular region calcium ion binding, heparin binding, protein binding Human Ensembl:ENSMUSP00000128308 THBS3 ENSEMBL UniProtKB {GO:0048471=PMID:11943589, GO:0003417=GO_REF:0000019, GO:0060346=GO_REF:0000019, GO:0043931=GO_REF:0000019, GO:0007160=PMID:7558000, GO:0005509=GO_REF:0000002, GO:0005576=GO_REF:0000002, GO:0007155=GO_REF:0000002, GO:0008201=PMID:8288588} Q2HIZ1 Thrombospondin-3 protein 20130413 {GO:0048471=IDA, GO:0003417=IEA, GO:0060346=IEA, GO:0043931=IEA, GO:0007160=NAS, GO:0005509=IEA, GO:0005576=IEA, GO:0007155=IEA, GO:0008201=IDA} bone trabecula formation, cell adhesion, cell-matrix adhesion, growth plate cartilage development, ossification involved in bone maturation extracellular region, perinuclear region of cytoplasm calcium ion binding, heparin binding Human Ensembl:ENSMUSP00000029682 THEG IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000019, GO:0051131=PMID:10747865, GO:0030154=GO_REF:0000037} Q9P2T0 Testicular haploid expressed gene protein protein 20130415 {GO:0005515=IPI, GO:0005634=IEA, GO:0007275=IEA, GO:0007283=IEA, GO:0051131=TAS, GO:0030154=IEA} cell differentiation, chaperone-mediated protein complex assembly, multicellular organismal development, spermatogenesis nucleus protein binding Human UniProtKB:Q99750 THEM4 HPA UniProtKB {GO:0008286=Reactome:REACT_498, GO:0048011=Reactome:REACT_11061, GO:0005886=Reactome:REACT_12567, GO:0048015=Reactome:REACT_12464, GO:0016290=PMID:22871024, GO:0005743=GO_REF:0000039, GO:0006915=PMID:19168129, GO:0032587=GO_REF:0000039, GO:0043231=GO_REF:0000052, GO:0005829=Reactome:REACT_1622, GO:0005739=PMID:19604401, GO:0005758=GO_REF:0000039, GO:0007173=Reactome:REACT_9417, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0043491=PMID:19168129, GO:0006631=PMID:22871024} Q5T1C6 Acyl-coenzyme A thioesterase THEM4 protein 20101115 {GO:0008286=TAS, GO:0048011=TAS, GO:0005886=TAS, GO:0048015=TAS, GO:0016290=IDA, GO:0005743=IEA, GO:0006915=IMP, GO:0032587=IEA, GO:0043231=IDA, GO:0005829=TAS, GO:0005739=IDA, GO:0005758=IEA, GO:0007173=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0043491=IMP, GO:0006631=IDA} apoptotic process, epidermal growth factor receptor signaling pathway, fatty acid metabolic process, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, protein kinase B signaling cascade cytosol, intracellular membrane-bounded organelle, mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrion, plasma membrane, ruffle membrane palmitoyl-CoA hydrolase activity Human THEMIS UniProtKB UniProtKB {GO:0050852=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0043383=GO_REF:0000024, GO:0008180=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0043368=GO_REF:0000024} Q8N1K5 Protein THEMIS protein 20120717 {GO:0050852=ISS, GO:0005737=ISS, GO:0043383=ISS, GO:0008180=ISS, GO:0005634=ISS, GO:0043368=ISS} T cell receptor signaling pathway, negative T cell selection, positive T cell selection cytoplasm, nucleus, signalosome Human UniProtKB:Q8BGW0 THG1L BHF-UCL UniProtKB {GO:0005739=GO_REF:0000054, GO:0005737=GO_REF:0000024, GO:0000049=PMID:21059936, GO:0000287=PMID:21059936, GO:0051289=PMID:21059936, GO:0008193=PMID:21059936, GO:0005525=PMID:21059936, GO:0005524=PMID:21059936, GO:0008033=PMID:21059936, GO:0006400=GO_REF:0000024, GO:0042802=PMID:21059936} Q9NWX6 Probable tRNA(His) guanylyltransferase protein 20110718 {GO:0005739=IDA, GO:0005737=ISS, GO:0000049=TAS, GO:0000287=IDA, GO:0051289=IDA, GO:0008193=IDA, GO:0005525=IDA, GO:0005524=IDA, GO:0008033=IDA, GO:0006400=ISS, GO:0042802=IPI} protein homotetramerization, tRNA modification, tRNA processing cytoplasm, mitochondrion ATP binding, GTP binding, identical protein binding, magnesium ion binding, tRNA binding, tRNA guanylyltransferase activity Human THNSL1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q8IYQ7 Threonine synthase-like 1 protein 20090707 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human THNSL2 BHF-UCL UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0046360=PMID:17034760, GO:0016311=PMID:17034760, GO:0009071=PMID:17034760, GO:0030170=PMID:17034760, GO:0005575=GO_REF:0000015, GO:0070905=PMID:17034760, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037, GO:0016829=GO_REF:0000037} Q86YJ6 Threonine synthase-like 2 protein 20110715 {GO:0003674=ND, GO:0008150=ND, GO:0046360=ISS, GO:0016311=ISS, GO:0009071=ISS, GO:0030170=ISS, GO:0005575=ND, GO:0070905=ISS, GO:0005615=IEA, GO:0005125=IEA, GO:0016829=IEA} 2-oxobutyrate biosynthetic process, biological_process, dephosphorylation, serine family amino acid catabolic process cellular_component, extracellular space cytokine activity, lyase activity, molecular_function, pyridoxal phosphate binding, serine binding Human UniProtKB:Q80W22 THOC1 HPA UniProtKB {GO:0005515=PMID:15870275, GO:0006397=GO_REF:0000037, GO:0008380=GO_REF:0000037, GO:0006396=PMID:7525595, GO:0000347=PMID:15998806, GO:0003723=GO_REF:0000037, GO:0000346=PMID:15833825, GO:0005730=GO_REF:0000052, GO:0006915=PMID:10512864, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0016363=GO_REF:0000039, GO:0046784=PMID:18974867, GO:0007165=GO_REF:0000002, GO:0005737=PMID:15358532, GO:0006406=PMID:17190602, GO:0016607=GO_REF:0000039, GO:0032784=PMID:15870275, GO:0000445=PMID:15998806} Q96FV9 THO complex subunit 1 protein 20100326 {GO:0005515=IPI, GO:0006397=IEA, GO:0008380=IEA, GO:0006396=TAS, GO:0000347=IDA, GO:0003723=IEA, GO:0000346=IDA, GO:0005730=IDA, GO:0006915=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0006351=IEA, GO:0016363=IEA, GO:0046784=IDA, GO:0007165=IEA, GO:0005737=IDA, GO:0006406=IDA, GO:0016607=IEA, GO:0032784=IDA, GO:0000445=IDA} RNA processing, RNA splicing, apoptotic process, intronless viral mRNA export from host nucleus, mRNA export from nucleus, mRNA processing, regulation of DNA-dependent transcription, elongation, signal transduction, transcription, DNA-dependent THO complex, THO complex part of transcription export complex, cytoplasm, nuclear matrix, nuclear speck, nucleolus, nucleus, transcription export complex DNA binding, RNA binding, protein binding NOT Human THOC2 UniProtKB UniProtKB {GO:0005515=PMID:15870275, GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0000347=PMID:15998806, GO:0006406=PMID:17190602, GO:0000346=PMID:15998806, GO:0003723=GO_REF:0000037, GO:0000445=PMID:15998806, GO:0046784=PMID:18974867} Q8NI27 THO complex subunit 2 protein 20090818 {GO:0005515=IPI, GO:0008380=IEA, GO:0006397=IEA, GO:0000347=IDA, GO:0006406=IDA, GO:0000346=IDA, GO:0003723=IEA, GO:0000445=IDA, GO:0046784=IDA} RNA splicing, intronless viral mRNA export from host nucleus, mRNA export from nucleus, mRNA processing THO complex, THO complex part of transcription export complex, transcription export complex RNA binding, protein binding Human UniProtKB:Q96FV9 THOC3 UniProtKB UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0006406=PMID:17190602, GO:0000346=PMID:15833825, GO:0003723=GO_REF:0000037, GO:0046784=PMID:18974867} Q96J01 THO complex subunit 3 protein 20090818 {GO:0008380=IEA, GO:0006397=IEA, GO:0006406=IDA, GO:0000346=IDA, GO:0003723=IEA, GO:0046784=IDA} RNA splicing, intronless viral mRNA export from host nucleus, mRNA export from nucleus, mRNA processing transcription export complex RNA binding Human THOC5 HPA UniProtKB {GO:0006397=GO_REF:0000037, GO:0008380=GO_REF:0000037, GO:0005515=PMID:19059247, GO:0000347=PMID:15998806, GO:0003723=GO_REF:0000037, GO:0000346=PMID:15998806, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0060215=GO_REF:0000024, GO:0045650=GO_REF:0000019, GO:0046784=PMID:18974867, GO:0043231=GO_REF:0000052, GO:0005737=GO_REF:0000039, GO:0006406=PMID:17190602, GO:0030224=PMID:19015024, GO:0000445=PMID:15998806, GO:0045111=GO_REF:0000052} Q13769 THO complex subunit 5 homolog protein 20101115 {GO:0006397=IEA, GO:0008380=IEA, GO:0005515=IPI, GO:0000347=IDA, GO:0003723=IEA, GO:0000346=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0060215=ISS, GO:0045650=IEA, GO:0046784=IDA, GO:0043231=IDA, GO:0005737=IEA, GO:0006406=IDA, GO:0030224=IDA, GO:0000445=IDA, GO:0045111=IDA} RNA splicing, intronless viral mRNA export from host nucleus, mRNA export from nucleus, mRNA processing, monocyte differentiation, negative regulation of macrophage differentiation, primitive hemopoiesis THO complex, THO complex part of transcription export complex, cytoplasm, intermediate filament cytoskeleton, intracellular membrane-bounded organelle, nucleolus, nucleus, transcription export complex RNA binding, protein binding Human THOC6 UniProtKB UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0000347=PMID:15998806, GO:0006406=PMID:17190602, GO:0000346=PMID:15833825, GO:0003723=GO_REF:0000037, GO:0000445=PMID:15998806, GO:0046784=PMID:18974867} Q86W42 THO complex subunit 6 homolog protein 20090818 {GO:0008380=IEA, GO:0006397=IEA, GO:0000347=IDA, GO:0006406=IDA, GO:0000346=IDA, GO:0003723=IEA, GO:0000445=IDA, GO:0046784=IDA} RNA splicing, intronless viral mRNA export from host nucleus, mRNA export from nucleus, mRNA processing THO complex, THO complex part of transcription export complex, transcription export complex RNA binding Human THOC7 HPA UniProtKB {GO:0005515=PMID:19059247, GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0000347=PMID:15998806, GO:0005737=GO_REF:0000052, GO:0006406=PMID:17190602, GO:0000346=PMID:15833825, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0000445=PMID:15998806, GO:0005634=GO_REF:0000052, GO:0046784=PMID:18974867} Q6I9Y2 THO complex subunit 7 homolog protein 20111111 {GO:0005515=IPI, GO:0008380=IEA, GO:0006397=IEA, GO:0000347=IDA, GO:0005737=IDA, GO:0006406=IDA, GO:0000346=IDA, GO:0003723=IEA, GO:0005730=IDA, GO:0000445=IDA, GO:0005634=IDA, GO:0046784=IDA} RNA splicing, intronless viral mRNA export from host nucleus, mRNA export from nucleus, mRNA processing THO complex, THO complex part of transcription export complex, cytoplasm, nucleolus, nucleus, transcription export complex RNA binding, protein binding Human THOP1 UniProtKB UniProtKB {GO:0042277=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0006508=GO_REF:0000037, GO:0004222=GO_REF:0000019, GO:0007243=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0006518=GO_REF:0000019} P52888 Thimet oligopeptidase protein 20130413 {GO:0042277=IEA, GO:0005737=IEA, GO:0006508=IEA, GO:0004222=IEA, GO:0007243=IEA, GO:0046872=IEA, GO:0006518=IEA} intracellular protein kinase cascade, peptide metabolic process, proteolysis cytoplasm metal ion binding, metalloendopeptidase activity, peptide binding Human UniProtKB-SubCell:SL-0086 THPO Reactome UniProtKB {GO:0005179=GO_REF:0000037, GO:0007596=Reactome:REACT_604, GO:0008283=GO_REF:0000002, GO:0030168=Reactome:REACT_798, GO:0030099=GO_REF:0000019, GO:0007275=PMID:8202159, GO:0005576=GO_REF:0000002, GO:0008083=PMID:8202159, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037} P40225 Thrombopoietin protein 20091019 {GO:0005179=IEA, GO:0007596=TAS, GO:0008283=IEA, GO:0030168=TAS, GO:0030099=IEA, GO:0007275=TAS, GO:0005576=IEA, GO:0008083=TAS, GO:0005615=IEA, GO:0005125=IEA} blood coagulation, cell proliferation, multicellular organismal development, myeloid cell differentiation, platelet activation extracellular region, extracellular space cytokine activity, growth factor activity, hormone activity Human THRA BHF-UCL UniProtKB {GO:0005515=PMID:16799563, GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_15525, GO:0003700=PMID:18052923, GO:0044212=PMID:18052923, GO:0006366=PMID:8710870, GO:0009409=GO_REF:0000019, GO:0008016=GO_REF:0000019, GO:0003707=GO_REF:0000002, GO:0010831=GO_REF:0000019, GO:2000143=PMID:8524305, GO:0005634=PMID:19158403, GO:0042994=GO_REF:0000019, GO:0030878=GO_REF:0000019, GO:0050994=GO_REF:0000019, GO:0070324=PMID:2879243, GO:0032403=GO_REF:0000019, GO:0005829=PMID:19158403, GO:0005737=GO_REF:0000019, GO:0008050=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0017055=PMID:8524305, GO:0007611=GO_REF:0000019, GO:0004879=GO_REF:0000019, GO:0045925=GO_REF:0000019, GO:0033032=GO_REF:0000019, GO:0002155=GO_REF:0000019, GO:0006357=PMID:18052923, GO:0019904=PMID:9653119, GO:0002153=GO_REF:0000019, GO:0031490=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0009755=PMID:18052923, GO:0001503=GO_REF:0000019, GO:0001502=GO_REF:0000019, GO:0030218=GO_REF:0000019, GO:0017025=PMID:8524305, GO:0005654=Reactome:REACT_19207, GO:0008270=GO_REF:0000002, GO:0004887=PMID:18052923, GO:0045892=PMID:8710870, GO:0008134=PMID:8524305} P10827 Thyroid hormone receptor alpha protein 20090330 {GO:0005515=IPI, GO:0010467=TAS, GO:0006367=TAS, GO:0003700=IDA, GO:0044212=IDA, GO:0006366=IDA, GO:0009409=IEA, GO:0008016=IEA, GO:0003707=IEA, GO:0010831=IEA, GO:2000143=IDA, GO:0005634=IDA, GO:0042994=IEA, GO:0030878=IEA, GO:0050994=IEA, GO:0070324=IPI, GO:0032403=IEA, GO:0005829=IDA, GO:0005737=IEA, GO:0008050=IEA, GO:0045944=IEA, GO:0017055=IDA, GO:0007611=IEA, GO:0004879=IEA, GO:0045925=IEA, GO:0033032=IEA, GO:0002155=IEA, GO:0006357=IDA, GO:0019904=IPI, GO:0002153=IEA, GO:0031490=IEA, GO:0043565=IEA, GO:0009755=IDA, GO:0001503=IEA, GO:0001502=IEA, GO:0030218=IEA, GO:0017025=IDA, GO:0005654=TAS, GO:0008270=IEA, GO:0004887=IDA, GO:0045892=IDA, GO:0008134=IPI} cartilage condensation, cytoplasmic sequestering of transcription factor, erythrocyte differentiation, female courtship behavior, gene expression, hormone-mediated signaling pathway, learning or memory, negative regulation of DNA-dependent transcription, initiation, negative regulation of RNA polymerase II transcriptional preinitiation complex assembly, negative regulation of transcription, DNA-dependent, ossification, positive regulation of female receptivity, positive regulation of myotube differentiation, positive regulation of transcription from RNA polymerase II promoter, regulation of heart contraction, regulation of lipid catabolic process, regulation of myeloid cell apoptotic process, regulation of thyroid hormone mediated signaling pathway, regulation of transcription from RNA polymerase II promoter, response to cold, thyroid gland development, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter cytoplasm, cytosol, nucleoplasm, nucleus TBP-class protein binding, chromatin DNA binding, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, protein binding, protein complex binding, protein domain specific binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity, steroid receptor RNA activator RNA binding, thyroid hormone binding, thyroid hormone receptor activity, transcription factor binding, transcription regulatory region DNA binding, zinc ion binding Human THRAP3 HPA UniProtKB {GO:0008380=GO_REF:0000037, GO:0051219=PMID:20932480, GO:0048026=PMID:20123736, GO:0005515=PMID:23084401, GO:0006367=PMID:12218053, GO:0005634=GO_REF:0000052, GO:0043231=GO_REF:0000052, GO:0046966=PMID:10198638, GO:0030374=PMID:10235266, GO:0030518=PMID:11867769, GO:0042809=PMID:10235266, GO:0000381=PMID:20932480, GO:0045944=PMID:12037571, GO:0004872=PMID:12218053, GO:0048255=PMID:18794151, GO:0035145=PMID:20123736, GO:0003712=PMID:12218053, GO:0006397=GO_REF:0000037, GO:0001104=PMID:10198638, GO:0003713=PMID:12037571, GO:0000956=PMID:20123736, GO:0005730=GO_REF:0000052, GO:0005524=GO_REF:0000037, GO:0016592=PMID:12037571, GO:0045893=PMID:10198638, GO:0030521=PMID:12218053} Q9Y2W1 Thyroid hormone receptor-associated protein 3 protein 20081203 {GO:0008380=IEA, GO:0051219=IDA, GO:0048026=IMP, GO:0005515=IPI, GO:0006367=IDA, GO:0005634=IDA, GO:0043231=IDA, GO:0046966=IDA, GO:0030374=NAS, GO:0030518=IDA, GO:0042809=NAS, GO:0000381=IMP, GO:0045944=IDA, GO:0004872=IDA, GO:0048255=IMP, GO:0035145=IDA, GO:0003712=IDA, GO:0006397=IEA, GO:0001104=IDA, GO:0003713=IDA, GO:0000956=IDA, GO:0005730=IDA, GO:0005524=IEA, GO:0016592=IDA, GO:0045893=IDA, GO:0030521=IDA} RNA splicing, androgen receptor signaling pathway, intracellular steroid hormone receptor signaling pathway, mRNA processing, mRNA stabilization, nuclear-transcribed mRNA catabolic process, positive regulation of mRNA splicing, via spliceosome, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of alternative mRNA splicing, via spliceosome, transcription initiation from RNA polymerase II promoter exon-exon junction complex, intracellular membrane-bounded organelle, mediator complex, nucleolus, nucleus ATP binding, RNA polymerase II transcription cofactor activity, ligand-dependent nuclear receptor transcription coactivator activity, phosphoprotein binding, protein binding, receptor activity, thyroid hormone receptor binding, transcription coactivator activity, transcription cofactor activity, vitamin D receptor binding Human THRB Reactome UniProtKB {GO:0005515=PMID:15100213, GO:0010467=Reactome:REACT_71, GO:0006367=Reactome:REACT_15525, GO:0003700=PMID:1618799, GO:0003714=PMID:1618799, GO:0007605=GO_REF:0000019, GO:0008016=GO_REF:0000019, GO:0003707=GO_REF:0000002, GO:0005634=PMID:1618799, GO:0000122=GO_REF:0000019, GO:0003677=PMID:1618799, GO:0006351=PMID:1618799, GO:0031490=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0008050=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0009887=GO_REF:0000019, GO:0005654=Reactome:REACT_19207, GO:0008270=GO_REF:0000002, GO:0007621=GO_REF:0000019, GO:0019899=PMID:12039952, GO:0004887=GO_REF:0000002} P10828 Thyroid hormone receptor beta protein 20130301 {GO:0005515=IPI, GO:0010467=TAS, GO:0006367=TAS, GO:0003700=NAS, GO:0003714=TAS, GO:0007605=IEA, GO:0008016=IEA, GO:0003707=IEA, GO:0005634=TAS, GO:0000122=IEA, GO:0003677=TAS, GO:0006351=TAS, GO:0031490=IEA, GO:0043565=IEA, GO:0008050=IEA, GO:0045944=IEA, GO:0009887=IEA, GO:0005654=TAS, GO:0008270=IEA, GO:0007621=IEA, GO:0019899=IPI, GO:0004887=IEA} female courtship behavior, gene expression, negative regulation of female receptivity, negative regulation of transcription from RNA polymerase II promoter, organ morphogenesis, positive regulation of transcription from RNA polymerase II promoter, regulation of heart contraction, sensory perception of sound, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent nucleoplasm, nucleus DNA binding, chromatin DNA binding, enzyme binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity, thyroid hormone receptor activity, transcription corepressor activity, zinc ion binding Human THRSP HPA UniProtKB {GO:0006629=GO_REF:0000037, GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0010866=GO_REF:0000019, GO:0046890=GO_REF:0000024, GO:0042803=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0005829=GO_REF:0000024} Q92748 Thyroid hormone-inducible hepatic protein protein 20110516 {GO:0006629=IEA, GO:0006355=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0010866=IEA, GO:0046890=ISS, GO:0042803=IEA, GO:0006351=IEA, GO:0005829=ISS} lipid metabolic process, regulation of lipid biosynthetic process, regulation of transcription, DNA-dependent, regulation of triglyceride biosynthetic process, transcription, DNA-dependent cytosol, nucleolus, nucleus protein homodimerization activity NOT Human THSD1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0009986=GO_REF:0000019, GO:0002244=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0071944=GO_REF:0000019} Q9NS62 Thrombospondin type-1 domain-containing protein 1 protein 20120912 {GO:0005737=IDA, GO:0009986=IEA, GO:0002244=IEA, GO:0005576=IEA, GO:0016021=IEA, GO:0071944=IEA} hematopoietic progenitor cell differentiation cell periphery, cell surface, cytoplasm, extracellular region, integral to membrane Human THSD7A UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0001525=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q9UPZ6 Thrombospondin type-1 domain-containing protein 7A protein 20130413 {GO:0005886=IEA, GO:0005576=IEA, GO:0016021=IEA, GO:0001525=IEA, GO:0030154=IEA} angiogenesis, cell differentiation extracellular region, integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 THSD7B UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9C0I4 Thrombospondin type-1 domain-containing protein 7B protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 THTPA HPA UniProtKB {GO:0005730=GO_REF:0000052, GO:0006767=Reactome:REACT_11238, GO:0005634=GO_REF:0000052, GO:0006091=PMID:11827967, GO:0044281=Reactome:REACT_111217, GO:0042723=Reactome:REACT_11117, GO:0050333=Reactome:REACT_25137, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_25137, GO:0005737=GO_REF:0000052, GO:0006772=PMID:11827967, GO:0016787=PMID:11827967, GO:0006766=Reactome:REACT_11193, GO:0016311=PMID:11827967} Q9BU02 Thiamine-triphosphatase protein 20101115 {GO:0005730=IDA, GO:0006767=TAS, GO:0005634=IDA, GO:0006091=NAS, GO:0044281=TAS, GO:0042723=TAS, GO:0050333=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0006772=TAS, GO:0016787=TAS, GO:0006766=TAS, GO:0016311=IDA} dephosphorylation, generation of precursor metabolites and energy, small molecule metabolic process, thiamine metabolic process, thiamine-containing compound metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cytoplasm, cytosol, nucleolus, nucleus hydrolase activity, metal ion binding, thiamin-triphosphatase activity Human THUMPD1 InterPro UniProtKB {GO:0003723=GO_REF:0000002} Q9NXG2 THUMP domain-containing protein 1 protein 20130413 {GO:0003723=IEA} RNA binding Human InterPro:IPR004114 THUMPD2 UniProtKB UniProtKB {GO:0003723=GO_REF:0000037, GO:0008168=GO_REF:0000037} Q9BTF0 THUMP domain-containing protein 2 protein 20130413 {GO:0003723=IEA, GO:0008168=IEA} RNA binding, methyltransferase activity Human UniProtKB-KW:KW-0489 THUMPD3 UniProtKB UniProtKB {GO:0003723=GO_REF:0000037, GO:0008168=GO_REF:0000037} Q9BV44 THUMP domain-containing protein 3 protein 20130413 {GO:0003723=IEA, GO:0008168=IEA} RNA binding, methyltransferase activity Human UniProtKB-KW:KW-0489 THY1 LIFEdb UniProtKB {GO:0005515=PMID:7513706, GO:0050852=GO_REF:0000024, GO:0034235=GO_REF:0000024, GO:0005886=GO_REF:0000024, GO:0005783=GO_REF:0000054, GO:0031362=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0030426=GO_REF:0000024, GO:0005829=GO_REF:0000019, GO:0016337=GO_REF:0000024, GO:0048041=GO_REF:0000024, GO:0007010=GO_REF:0000024, GO:0051281=GO_REF:0000024, GO:0030336=GO_REF:0000024, GO:0019901=GO_REF:0000019, GO:0046549=GO_REF:0000024, GO:0001525=GO_REF:0000024, GO:0005100=GO_REF:0000024, GO:0050860=GO_REF:0000024, GO:0043547=GO_REF:0000024, GO:0005178=PMID:15004192, GO:0005887=PMID:2864289, GO:0050870=GO_REF:0000024, GO:0045121=PMID:15093746, GO:0050771=GO_REF:0000024, GO:0006469=GO_REF:0000024, GO:0009897=GO_REF:0000024} P04216 Thy-1 membrane glycoprotein protein 20100607 {GO:0005515=IPI, GO:0050852=ISS, GO:0034235=ISS, GO:0005886=ISS, GO:0005783=IDA, GO:0031362=IEA, GO:0030425=IEA, GO:0030426=ISS, GO:0005829=IEA, GO:0016337=ISS, GO:0048041=ISS, GO:0007010=ISS, GO:0051281=ISS, GO:0030336=ISS, GO:0019901=IEA, GO:0046549=ISS, GO:0001525=ISS, GO:0005100=ISS, GO:0050860=ISS, GO:0043547=ISS, GO:0005178=IPI, GO:0005887=TAS, GO:0050870=ISS, GO:0045121=NAS, GO:0050771=ISS, GO:0006469=ISS, GO:0009897=ISS} T cell receptor signaling pathway, angiogenesis, cell-cell adhesion, cytoskeleton organization, focal adhesion assembly, negative regulation of T cell receptor signaling pathway, negative regulation of axonogenesis, negative regulation of cell migration, negative regulation of protein kinase activity, positive regulation of GTPase activity, positive regulation of T cell activation, positive regulation of release of sequestered calcium ion into cytosol, retinal cone cell development anchored to external side of plasma membrane, cytosol, dendrite, endoplasmic reticulum, external side of plasma membrane, growth cone, integral to plasma membrane, membrane raft, plasma membrane GPI anchor binding, Rho GTPase activator activity, integrin binding, protein binding, protein kinase binding Human THYN1 HGNC UniProtKB {GO:0005634=PMID:14601557} Q9P016 Thymocyte nuclear protein 1 protein 20051027 {GO:0005634=ISS} nucleus Human UniProtKB:Q91YJ3 TIA1 InterPro UniProtKB {GO:0005515=PMID:7544399, GO:0042036=GO_REF:0000019, GO:0017148=GO_REF:0000019, GO:0048024=PMID:11106748, GO:0000166=GO_REF:0000002, GO:0010494=GO_REF:0000019, GO:0008143=PMID:1934064, GO:0006915=GO_REF:0000037, GO:0017091=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0006917=PMID:1934064, GO:0003676=GO_REF:0000002} Q96B58 Nucleolysin TIA-1 isoform p40 protein 20130413 {GO:0005515=IPI, GO:0042036=IEA, GO:0017148=IEA, GO:0048024=IDA, GO:0000166=IEA, GO:0010494=IEA, GO:0008143=TAS, GO:0006915=IEA, GO:0017091=IEA, GO:0005634=IEA, GO:0006917=TAS, GO:0003676=IEA} apoptotic process, induction of apoptosis, negative regulation of cytokine biosynthetic process, negative regulation of translation, regulation of mRNA splicing, via spliceosome cytoplasmic stress granule, nucleus AU-rich element binding, nucleic acid binding, nucleotide binding, poly(A) RNA binding, protein binding Human InterPro:IPR000504 TIAF1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0043066=PMID:9918798, GO:0007249=PMID:9918798, GO:0006915=GO_REF:0000037, GO:0005634=PMID:9918798} O95411 TGFB1-induced anti-apoptotic factor 1 protein 20010912 {GO:0003674=ND, GO:0043066=IDA, GO:0007249=IDA, GO:0006915=IEA, GO:0005634=NAS} I-kappaB kinase/NF-kappaB cascade, apoptotic process, negative regulation of apoptotic process nucleus molecular_function Human TIAL1 InterPro UniProtKB {GO:0008284=GO_REF:0000019, GO:0006357=PMID:9207209, GO:0010494=GO_REF:0000024, GO:0003723=PMID:1326761, GO:0017145=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000024, GO:0006952=PMID:1326761, GO:0006917=PMID:1326761, GO:0003676=GO_REF:0000002, GO:0007281=GO_REF:0000019, GO:0005764=PMID:1326761, GO:0005737=GO_REF:0000024, GO:0000166=GO_REF:0000002, GO:0017091=GO_REF:0000019} Q49AS9 Nucleolysin TIAR protein 20130413 {GO:0008284=IEA, GO:0006357=TAS, GO:0010494=ISS, GO:0003723=TAS, GO:0017145=IEA, GO:0006915=IEA, GO:0005634=ISS, GO:0006952=TAS, GO:0006917=TAS, GO:0003676=IEA, GO:0007281=IEA, GO:0005764=TAS, GO:0005737=ISS, GO:0000166=IEA, GO:0017091=IEA} apoptotic process, defense response, germ cell development, induction of apoptosis, positive regulation of cell proliferation, regulation of transcription from RNA polymerase II promoter, stem cell division cytoplasm, cytoplasmic stress granule, lysosome, nucleus AU-rich element binding, RNA binding, nucleic acid binding, nucleotide binding Human InterPro:IPR000504 TIAM1 Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0005886=GO_REF:0000019, GO:0048013=GO_REF:0000019, GO:0007264=Reactome:REACT_11044, GO:0035023=GO_REF:0000002, GO:0006915=Reactome:REACT_13638, GO:0097190=Reactome:REACT_13720, GO:0005829=Reactome:REACT_19216, GO:0005085=GO_REF:0000019, GO:0005622=GO_REF:0000002, GO:0035556=GO_REF:0000002, GO:0005543=GO_REF:0000019, GO:0046875=GO_REF:0000019, GO:0005911=PMID:20332120, GO:0050772=GO_REF:0000019, GO:0005057=GO_REF:0000002, GO:0005089=GO_REF:0000002} Q13009 T-lymphoma invasion and metastasis-inducing protein 1 protein 20130301 {GO:0051056=TAS, GO:0048011=TAS, GO:0005886=IEA, GO:0048013=IEA, GO:0007264=TAS, GO:0035023=IEA, GO:0006915=TAS, GO:0097190=TAS, GO:0005829=TAS, GO:0005085=IEA, GO:0005622=IEA, GO:0035556=IEA, GO:0005543=IEA, GO:0046875=IEA, GO:0005911=IDA, GO:0050772=IEA, GO:0005057=IEA, GO:0005089=IEA} apoptotic process, apoptotic signaling pathway, ephrin receptor signaling pathway, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, positive regulation of axonogenesis, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction cell-cell junction, cytosol, intracellular, plasma membrane Rho guanyl-nucleotide exchange factor activity, ephrin receptor binding, guanyl-nucleotide exchange factor activity, phospholipid binding, receptor signaling protein activity Human TIAM2 Reactome UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0007264=Reactome:REACT_11044, GO:0035023=GO_REF:0000002, GO:0006915=Reactome:REACT_13638, GO:0044281=Reactome:REACT_111217, GO:0030175=GO_REF:0000039, GO:0097190=Reactome:REACT_13720, GO:0030027=GO_REF:0000039, GO:0005829=Reactome:REACT_115593, GO:0030426=GO_REF:0000039, GO:0035556=GO_REF:0000002, GO:0005085=PMID:10512681, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0016020=GO_REF:0000019, GO:0005057=GO_REF:0000002, GO:0005089=GO_REF:0000002, GO:0044255=Reactome:REACT_22279, GO:0005096=GO_REF:0000019} Q8IVF5 T-lymphoma invasion and metastasis-inducing protein 2 protein 20130301 {GO:0051056=TAS, GO:0048011=TAS, GO:0007264=TAS, GO:0035023=IEA, GO:0006915=TAS, GO:0044281=TAS, GO:0030175=IEA, GO:0097190=TAS, GO:0030027=IEA, GO:0005829=TAS, GO:0030426=IEA, GO:0035556=IEA, GO:0005085=TAS, GO:0005622=IEA, GO:0005737=IEA, GO:0005543=IEA, GO:0016020=IEA, GO:0005057=IEA, GO:0005089=IEA, GO:0044255=TAS, GO:0005096=IEA} apoptotic process, apoptotic signaling pathway, cellular lipid metabolic process, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction, small molecule metabolic process cytoplasm, cytosol, filopodium, growth cone, intracellular, lamellipodium, membrane GTPase activator activity, Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, phospholipid binding, receptor signaling protein activity Human TICAM1 BHF-UCL UniProtKB {GO:0043496=GO_REF:0000019, GO:0032755=GO_REF:0000019, GO:0005515=PMID:15142865, GO:0034142=Reactome:REACT_6894, GO:0030890=GO_REF:0000019, GO:0007249=Reactome:REACT_25351, GO:0032092=GO_REF:0000019, GO:0045429=GO_REF:0000019, GO:0005829=Reactome:REACT_150447, GO:0002756=Reactome:REACT_6809, GO:0051607=GO_REF:0000019, GO:0006954=GO_REF:0000037, GO:0051092=GO_REF:0000019, GO:0002281=GO_REF:0000019, GO:0031398=GO_REF:0000019, GO:0032481=GO_REF:0000019, GO:0004871=PMID:12761501, GO:0043123=PMID:14982987, GO:0034138=Reactome:REACT_6783, GO:0031663=GO_REF:0000019, GO:0032760=GO_REF:0000019, GO:0019901=PMID:14530355, GO:0006915=GO_REF:0000037, GO:0002224=Reactome:REACT_6966, GO:0045359=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0035666=Reactome:REACT_25281, GO:0043330=GO_REF:0000019, GO:0010008=Reactome:REACT_150447, GO:0045080=GO_REF:0000019} Q8IUC6 TIR domain-containing adapter molecule 1 protein 20110201 {GO:0043496=IEA, GO:0032755=IEA, GO:0005515=IPI, GO:0034142=TAS, GO:0030890=IEA, GO:0007249=TAS, GO:0032092=IEA, GO:0045429=IEA, GO:0005829=TAS, GO:0002756=TAS, GO:0051607=IEA, GO:0006954=IEA, GO:0051092=IEA, GO:0002281=IEA, GO:0031398=IEA, GO:0032481=IEA, GO:0004871=IMP, GO:0043123=IMP, GO:0034138=TAS, GO:0031663=IEA, GO:0032760=IEA, GO:0019901=IPI, GO:0006915=IEA, GO:0002224=TAS, GO:0045359=IEA, GO:0045087=TAS, GO:0035666=TAS, GO:0043330=IEA, GO:0010008=TAS, GO:0045080=IEA} I-kappaB kinase/NF-kappaB cascade, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, apoptotic process, defense response to virus, inflammatory response, innate immune response, lipopolysaccharide-mediated signaling pathway, macrophage activation involved in immune response, positive regulation of B cell proliferation, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of chemokine biosynthetic process, positive regulation of interferon-beta biosynthetic process, positive regulation of interleukin-6 production, positive regulation of nitric oxide biosynthetic process, positive regulation of protein binding, positive regulation of protein ubiquitination, positive regulation of tumor necrosis factor production, positive regulation of type I interferon production, regulation of protein homodimerization activity, response to exogenous dsRNA, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor signaling pathway cytosol, endosome membrane protein binding, protein kinase binding, signal transducer activity Human UniProtKB:P21580 TICAM2 Reactome UniProtKB {GO:0005794=GO_REF:0000039, GO:0034142=Reactome:REACT_6894, GO:0005886=Reactome:REACT_121217, GO:0007249=Reactome:REACT_25351, GO:0002224=Reactome:REACT_6966, GO:0002756=Reactome:REACT_6809, GO:0006954=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0035666=Reactome:REACT_25281, GO:0004871=PMID:12761501, GO:0043123=PMID:12761501, GO:0034138=Reactome:REACT_6783, GO:0010008=Reactome:REACT_150447} Q86XR7 TIR domain-containing adapter molecule 2 protein 20130213 {GO:0005794=IEA, GO:0034142=TAS, GO:0005886=TAS, GO:0007249=TAS, GO:0002224=TAS, GO:0002756=TAS, GO:0006954=IEA, GO:0045087=TAS, GO:0035666=TAS, GO:0004871=IMP, GO:0043123=IMP, GO:0034138=TAS, GO:0010008=TAS} I-kappaB kinase/NF-kappaB cascade, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, inflammatory response, innate immune response, positive regulation of I-kappaB kinase/NF-kappaB cascade, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor signaling pathway Golgi apparatus, endosome membrane, plasma membrane signal transducer activity Human TIE1 IntAct UniProtKB {GO:0005515=PMID:21982860, GO:0030336=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0001525=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0001701=GO_REF:0000019, GO:0007165=PMID:1312667, GO:0005887=PMID:1312667, GO:0016525=GO_REF:0000019, GO:0045026=GO_REF:0000019, GO:0007498=PMID:7596437, GO:0016021=GO_REF:0000038, GO:0032526=GO_REF:0000019, GO:0004713=GO_REF:0000038, GO:0004714=GO_REF:0000003} P35590 Tyrosine-protein kinase receptor Tie-1 protein 20130415 {GO:0005515=IPI, GO:0030336=IEA, GO:0005886=IEA, GO:0001525=IEA, GO:0005524=IEA, GO:0001701=IEA, GO:0007165=TAS, GO:0005887=TAS, GO:0016525=IEA, GO:0045026=IEA, GO:0007498=TAS, GO:0016021=IEA, GO:0032526=IEA, GO:0004713=IEA, GO:0004714=IEA} angiogenesis, in utero embryonic development, mesoderm development, negative regulation of angiogenesis, negative regulation of cell migration, plasma membrane fusion, response to retinoic acid, signal transduction integral to membrane, integral to plasma membrane, plasma membrane ATP binding, protein binding, protein tyrosine kinase activity, transmembrane receptor protein tyrosine kinase activity Human UniProtKB:Q15238 TIFA IntAct UniProtKB {GO:0005515=PMID:16643855, GO:0007249=GO_REF:0000019} Q96CG3 TRAF-interacting protein with FHA domain-containing protein A protein 20130415 {GO:0005515=IPI, GO:0007249=IEA} I-kappaB kinase/NF-kappaB cascade protein binding Human UniProtKB:Q5TAX3-1 TIFAB null null {} null null null null {} null null null TIGD1 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037} Q96MW7 Tigger transposable element-derived protein 1 protein 20130413 {GO:0005634=IEA, GO:0003677=IEA} nucleus DNA binding Human UniProtKB-SubCell:SL-0191 TIGD4 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037} Q8IY51 Tigger transposable element-derived protein 4 protein 20130413 {GO:0005634=IEA, GO:0003677=IEA} nucleus DNA binding Human UniProtKB-SubCell:SL-0191 TIGD5 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005634=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0003677=GO_REF:0000037} Q53EQ6 Tigger transposable element-derived protein 5 protein 20101001 {GO:0003674=ND, GO:0008150=ND, GO:0005634=IEA, GO:0005575=ND, GO:0003677=IEA} biological_process cellular_component, nucleus DNA binding, molecular_function Human TIGD7 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037} Q6NT04 Tigger transposable element-derived protein 7 protein 20130413 {GO:0005634=IEA, GO:0003677=IEA} nucleus DNA binding Human UniProtKB-SubCell:SL-0191 TIMELESS IntAct UniProtKB {GO:0005515=PMID:15798197, GO:0000790=PMID:17102137, GO:0033261=PMID:17102137, GO:0046982=GO_REF:0000019, GO:0030324=GO_REF:0000019, GO:0005634=PMID:17102137, GO:0000122=GO_REF:0000019, GO:0009790=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0006974=GO_REF:0000037, GO:0042803=GO_REF:0000019, GO:0007067=GO_REF:0000037, GO:0009582=PMID:9856466, GO:0042127=PMID:17102137, GO:0009628=PMID:9891984, GO:0007623=GO_REF:0000024, GO:0048754=GO_REF:0000019, GO:0002009=GO_REF:0000024, GO:0045892=PMID:9856465, GO:0051301=GO_REF:0000037} Q9UNS1 Protein timeless homolog protein 20130415 {GO:0005515=IPI, GO:0000790=IDA, GO:0033261=IMP, GO:0046982=IEA, GO:0030324=IEA, GO:0005634=IDA, GO:0000122=IEA, GO:0009790=IEA, GO:0006351=IEA, GO:0006974=IEA, GO:0042803=IEA, GO:0007067=IEA, GO:0009582=TAS, GO:0042127=IMP, GO:0009628=TAS, GO:0007623=ISS, GO:0048754=IEA, GO:0002009=ISS, GO:0045892=IDA, GO:0051301=IEA} branching morphogenesis of an epithelial tube, cell division, circadian rhythm, detection of abiotic stimulus, embryo development, lung development, mitosis, morphogenesis of an epithelium, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, regulation of S phase, regulation of cell proliferation, response to DNA damage stimulus, response to abiotic stimulus, transcription, DNA-dependent nuclear chromatin, nucleus protein binding, protein heterodimerization activity, protein homodimerization activity Human UniProtKB:O14757 TIMM10 HPA UniProtKB {GO:0005215=PMID:16387659, GO:0007605=PMID:10552927, GO:0006626=Reactome:REACT_118595, GO:0005743=PMID:14726512, GO:0051087=PMID:16387659, GO:0042719=PMID:14726512, GO:0042803=PMID:16387659, GO:0005739=GO_REF:0000052, GO:0005744=PMID:10552927, GO:0005758=PMID:14726512, GO:0045039=PMID:16387659, GO:0008270=PMID:10552927, GO:0072321=PMID:16387659, GO:0044267=Reactome:REACT_17015} P62072 Mitochondrial import inner membrane translocase subunit Tim10 protein 20110516 {GO:0005215=IDA, GO:0007605=TAS, GO:0006626=TAS, GO:0005743=IDA, GO:0051087=IPI, GO:0042719=IDA, GO:0042803=IPI, GO:0005739=IDA, GO:0005744=TAS, GO:0005758=TAS, GO:0045039=IDA, GO:0008270=TAS, GO:0072321=IDA, GO:0044267=TAS} cellular protein metabolic process, chaperone-mediated protein transport, protein import into mitochondrial inner membrane, protein targeting to mitochondrion, sensory perception of sound mitochondrial inner membrane, mitochondrial inner membrane presequence translocase complex, mitochondrial intermembrane space, mitochondrial intermembrane space protein transporter complex, mitochondrion chaperone binding, protein homodimerization activity, transporter activity, zinc ion binding Human TIMM13 BHF-UCL UniProtKB {GO:0005739=GO_REF:0000038, GO:0007605=PMID:10552927, GO:0006626=Reactome:REACT_118595, GO:0005743=GO_REF:0000039, GO:0042719=PMID:10552927, GO:0008270=PMID:10552927, GO:0072321=PMID:16387659, GO:0015031=GO_REF:0000038, GO:0044267=Reactome:REACT_17015, GO:0046872=GO_REF:0000038} Q9Y5L4 Mitochondrial import inner membrane translocase subunit Tim13 protein 20110715 {GO:0005739=IEA, GO:0007605=TAS, GO:0006626=TAS, GO:0005743=IEA, GO:0042719=TAS, GO:0008270=TAS, GO:0072321=TAS, GO:0015031=IEA, GO:0044267=TAS, GO:0046872=IEA} cellular protein metabolic process, chaperone-mediated protein transport, protein targeting to mitochondrion, protein transport, sensory perception of sound mitochondrial inner membrane, mitochondrial intermembrane space protein transporter complex, mitochondrion metal ion binding, zinc ion binding Human TIMM17A BHF-UCL UniProtKB {GO:0005744=PMID:10339406, GO:0015450=GO_REF:0000002, GO:0006626=Reactome:REACT_118595, GO:0031305=PMID:10339406, GO:0044267=Reactome:REACT_17015} Q99595 Mitochondrial import inner membrane translocase subunit Tim17-A protein 20110714 {GO:0005744=IDA, GO:0015450=IEA, GO:0006626=TAS, GO:0031305=IDA, GO:0044267=TAS} cellular protein metabolic process, protein targeting to mitochondrion integral to mitochondrial inner membrane, mitochondrial inner membrane presequence translocase complex P-P-bond-hydrolysis-driven protein transmembrane transporter activity Human TIMM17B HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005744=PMID:10339406, GO:0015450=GO_REF:0000002, GO:0015630=GO_REF:0000052, GO:0006626=Reactome:REACT_118595, GO:0005743=GO_REF:0000019, GO:0031305=PMID:10339406, GO:0016021=GO_REF:0000038, GO:0044267=Reactome:REACT_17015} O60830 Mitochondrial import inner membrane translocase subunit Tim17-B protein 20101115 {GO:0005739=IDA, GO:0005744=IDA, GO:0015450=IEA, GO:0015630=IDA, GO:0006626=TAS, GO:0005743=IEA, GO:0031305=IDA, GO:0016021=IEA, GO:0044267=TAS} cellular protein metabolic process, protein targeting to mitochondrion integral to membrane, integral to mitochondrial inner membrane, microtubule cytoskeleton, mitochondrial inner membrane, mitochondrial inner membrane presequence translocase complex, mitochondrion P-P-bond-hydrolysis-driven protein transmembrane transporter activity Human TIMM21 BHF-UCL UniProtKB {GO:0033617=PMID:23260140, GO:0005744=PMID:23260140, GO:0003674=GO_REF:0000015, GO:0032981=PMID:23260140, GO:0006626=Reactome:REACT_118595, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037, GO:0030150=PMID:23260140, GO:0044267=Reactome:REACT_17015} Q9BVV7 Mitochondrial import inner membrane translocase subunit Tim21 protein 20120710 {GO:0033617=IMP, GO:0005744=IDA, GO:0003674=ND, GO:0032981=IMP, GO:0006626=TAS, GO:0005575=ND, GO:0016021=IEA, GO:0030150=IMP, GO:0044267=TAS} cellular protein metabolic process, mitochondrial respiratory chain complex I assembly, mitochondrial respiratory chain complex IV assembly, protein import into mitochondrial matrix, protein targeting to mitochondrion cellular_component, integral to membrane, mitochondrial inner membrane presequence translocase complex molecular_function Human TIMM22 BHF-UCL UniProtKB {GO:0045039=PMID:14726512, GO:0006626=Reactome:REACT_118595, GO:0005743=PMID:14726512, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0015266=PMID:14726512} Q9Y584 Mitochondrial import inner membrane translocase subunit Tim22 protein 20110714 {GO:0045039=TAS, GO:0006626=TAS, GO:0005743=TAS, GO:0016021=IEA, GO:0044267=TAS, GO:0015266=TAS} cellular protein metabolic process, protein import into mitochondrial inner membrane, protein targeting to mitochondrion integral to membrane, mitochondrial inner membrane protein channel activity Human TIMM23 HPA UniProtKB {GO:0005744=PMID:10339406, GO:0005515=PMID:15044455, GO:0005739=GO_REF:0000052, GO:0005758=PMID:15044455, GO:0015450=GO_REF:0000002, GO:0006626=Reactome:REACT_118595, GO:0005743=PMID:14726512, GO:0031305=PMID:10339406, GO:0016021=GO_REF:0000038, GO:0044267=Reactome:REACT_17015} O14925 Mitochondrial import inner membrane translocase subunit Tim23 protein 20101115 {GO:0005744=IDA, GO:0005515=IPI, GO:0005739=IDA, GO:0005758=IDA, GO:0015450=IEA, GO:0006626=TAS, GO:0005743=TAS, GO:0031305=IDA, GO:0016021=IEA, GO:0044267=TAS} cellular protein metabolic process, protein targeting to mitochondrion integral to membrane, integral to mitochondrial inner membrane, mitochondrial inner membrane, mitochondrial inner membrane presequence translocase complex, mitochondrial intermembrane space, mitochondrion P-P-bond-hydrolysis-driven protein transmembrane transporter activity, protein binding Human TIMM23B BHF-UCL UniProtKB {GO:0005744=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0015450=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037, GO:0006886=GO_REF:0000002} Q5SRD1 Putative mitochondrial import inner membrane translocase subunit Tim23B protein 20110714 {GO:0005744=IEA, GO:0003674=ND, GO:0008150=ND, GO:0015450=IEA, GO:0005575=ND, GO:0016021=IEA, GO:0006886=IEA} biological_process, intracellular protein transport cellular_component, integral to membrane, mitochondrial inner membrane presequence translocase complex P-P-bond-hydrolysis-driven protein transmembrane transporter activity, molecular_function Human TIMM44 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005515=PMID:12620389, GO:0015450=GO_REF:0000002, GO:0005759=PMID:10339406, GO:0006626=Reactome:REACT_118595, GO:0005743=PMID:10339406, GO:0044267=Reactome:REACT_17015, GO:0005524=GO_REF:0000037} O43615 Mitochondrial import inner membrane translocase subunit TIM44 protein 20110516 {GO:0005739=IDA, GO:0005515=IPI, GO:0015450=IEA, GO:0005759=IDA, GO:0006626=TAS, GO:0005743=IDA, GO:0044267=TAS, GO:0005524=IEA} cellular protein metabolic process, protein targeting to mitochondrion mitochondrial inner membrane, mitochondrial matrix, mitochondrion ATP binding, P-P-bond-hydrolysis-driven protein transmembrane transporter activity, protein binding Human TIMM50 GOC UniProtKB {GO:0005515=PMID:12620389, GO:0005134=PMID:15044455, GO:0003723=GO_REF:0000037, GO:0006626=Reactome:REACT_118595, GO:0005743=PMID:15044455, GO:0001836=PMID:15044455, GO:0015031=GO_REF:0000002, GO:0035335=PMID:15044455, GO:0005744=PMID:15044455, GO:0006470=PMID:15044455, GO:0016607=PMID:16008839, GO:0043021=PMID:16008839, GO:0004721=PMID:15044455, GO:0007006=PMID:15044455, GO:0016021=GO_REF:0000037, GO:0004722=PMID:15044455, GO:0044267=Reactome:REACT_17015, GO:0004725=PMID:15044455} Q3ZCQ8 Mitochondrial import inner membrane translocase subunit TIM50 protein 20130413 {GO:0005515=IPI, GO:0005134=IDA, GO:0003723=IEA, GO:0006626=TAS, GO:0005743=IDA, GO:0001836=IDA, GO:0015031=IEA, GO:0035335=IDA, GO:0005744=IPI, GO:0006470=IDA, GO:0016607=IDA, GO:0043021=IDA, GO:0004721=IDA, GO:0007006=IMP, GO:0016021=IEA, GO:0004722=IDA, GO:0044267=TAS, GO:0004725=IDA} cellular protein metabolic process, mitochondrial membrane organization, peptidyl-tyrosine dephosphorylation, protein dephosphorylation, protein targeting to mitochondrion, protein transport, release of cytochrome c from mitochondria integral to membrane, mitochondrial inner membrane, mitochondrial inner membrane presequence translocase complex, nuclear speck RNA binding, interleukin-2 receptor binding, phosphoprotein phosphatase activity, protein binding, protein serine/threonine phosphatase activity, protein tyrosine phosphatase activity, ribonucleoprotein complex binding Human TIMM8A HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005758=PMID:14726512, GO:0006626=Reactome:REACT_118595, GO:0005743=GO_REF:0000039, GO:0072321=PMID:16387659, GO:0044267=Reactome:REACT_17015, GO:0046872=GO_REF:0000037, GO:0007399=PMID:8841189} O60220 Mitochondrial import inner membrane translocase subunit Tim8 A protein 20101115 {GO:0005739=IDA, GO:0005758=IDA, GO:0006626=TAS, GO:0005743=IEA, GO:0072321=TAS, GO:0044267=TAS, GO:0046872=IEA, GO:0007399=TAS} cellular protein metabolic process, chaperone-mediated protein transport, nervous system development, protein targeting to mitochondrion mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrion metal ion binding Human TIMM8B BHF-UCL UniProtKB {GO:0005739=GO_REF:0000019, GO:0007605=PMID:10552927, GO:0006626=Reactome:REACT_118595, GO:0005743=GO_REF:0000039, GO:0042719=PMID:10552927, GO:0008270=PMID:10552927, GO:0072321=PMID:16387659, GO:0015031=GO_REF:0000038, GO:0044267=Reactome:REACT_17015, GO:0046872=GO_REF:0000038} Q9Y5J9 Mitochondrial import inner membrane translocase subunit Tim8 B protein 20110715 {GO:0005739=IEA, GO:0007605=TAS, GO:0006626=TAS, GO:0005743=IEA, GO:0042719=TAS, GO:0008270=TAS, GO:0072321=TAS, GO:0015031=IEA, GO:0044267=TAS, GO:0046872=IEA} cellular protein metabolic process, chaperone-mediated protein transport, protein targeting to mitochondrion, protein transport, sensory perception of sound mitochondrial inner membrane, mitochondrial intermembrane space protein transporter complex, mitochondrion metal ion binding, zinc ion binding Human TIMM9 HPA UniProtKB {GO:0005215=PMID:16387659, GO:0007605=PMID:10552927, GO:0006626=Reactome:REACT_118595, GO:0005743=PMID:14726512, GO:0051087=PMID:16387659, GO:0042719=PMID:14726512, GO:0015031=GO_REF:0000038, GO:0046872=GO_REF:0000038, GO:0042803=PMID:16387659, GO:0005739=GO_REF:0000052, GO:0005758=PMID:14726512, GO:0045039=PMID:16387659, GO:0008270=PMID:10552927, GO:0072321=PMID:16387659, GO:0044267=Reactome:REACT_17015} Q9Y5J7 Mitochondrial import inner membrane translocase subunit Tim9 protein 20080205 {GO:0005215=IDA, GO:0007605=TAS, GO:0006626=TAS, GO:0005743=IDA, GO:0051087=IPI, GO:0042719=IDA, GO:0015031=IEA, GO:0046872=IEA, GO:0042803=IPI, GO:0005739=IDA, GO:0005758=TAS, GO:0045039=IDA, GO:0008270=TAS, GO:0072321=IDA, GO:0044267=TAS} cellular protein metabolic process, chaperone-mediated protein transport, protein import into mitochondrial inner membrane, protein targeting to mitochondrion, protein transport, sensory perception of sound mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial intermembrane space protein transporter complex, mitochondrion chaperone binding, metal ion binding, protein homodimerization activity, transporter activity, zinc ion binding Human TIMMDC1 LIFEdb UniProtKB {GO:0005739=GO_REF:0000054, GO:0016021=GO_REF:0000037} Q9NPL8 Translocase of inner mitochondrial membrane domain-containing protein 1 protein 20100607 {GO:0005739=IDA, GO:0016021=IEA} integral to membrane, mitochondrion Human TIMP1 UniProtKB UniProtKB {GO:0005515=PMID:2251898, GO:0043066=GO_REF:0000019, GO:0008284=PMID:3839290, GO:0051045=PMID:12714508, GO:0007568=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0043434=GO_REF:0000019, GO:0005576=GO_REF:0000038, GO:0046872=GO_REF:0000037, GO:0005604=GO_REF:0000019, GO:0043249=GO_REF:0000037, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0007596=Reactome:REACT_604, GO:0008191=GO_REF:0000002, GO:0042060=GO_REF:0000019, GO:0002576=Reactome:REACT_318, GO:0031093=Reactome:REACT_21351, GO:0034097=GO_REF:0000019, GO:0001775=GO_REF:0000019, GO:1901164=PMID:21356369} Q5H9B5 Metalloproteinase inhibitor 1 protein 20130413 {GO:0005515=IPI, GO:0043066=IEA, GO:0008284=TAS, GO:0051045=IDA, GO:0007568=IEA, GO:0030168=TAS, GO:0043434=IEA, GO:0005576=IEA, GO:0046872=IEA, GO:0005604=IEA, GO:0043249=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0007596=TAS, GO:0008191=IEA, GO:0042060=IEA, GO:0002576=TAS, GO:0031093=TAS, GO:0034097=IEA, GO:0001775=IEA, GO:1901164=IMP} aging, blood coagulation, cell activation, erythrocyte maturation, extracellular matrix disassembly, extracellular matrix organization, negative regulation of apoptotic process, negative regulation of membrane protein ectodomain proteolysis, negative regulation of trophoblast cell migration, platelet activation, platelet degranulation, positive regulation of cell proliferation, response to cytokine stimulus, response to peptide hormone stimulus, wound healing basement membrane, extracellular region, platelet alpha granule lumen metal ion binding, metalloendopeptidase inhibitor activity, protein binding Human UniProtKB-KW:KW-0964 TIMP2 Reactome UniProtKB {GO:0008285=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0030426=GO_REF:0000019, GO:0046580=GO_REF:0000019, GO:0022617=Reactome:REACT_118572, GO:0030198=Reactome:REACT_118779, GO:0043025=GO_REF:0000019, GO:0034097=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0071310=GO_REF:0000019, GO:0032487=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0045762=GO_REF:0000019, GO:0005576=Reactome:REACT_118860, GO:0007417=GO_REF:0000019, GO:0005604=GO_REF:0000019, GO:0045861=GO_REF:0000019, GO:0005178=GO_REF:0000019, GO:0045666=GO_REF:0000019, GO:0045930=GO_REF:0000019, GO:0008191=GO_REF:0000019, GO:0008047=GO_REF:0000019, GO:0043410=GO_REF:0000019} P16035 Metalloproteinase inhibitor 2 protein 20130213 {GO:0008285=IEA, GO:0005615=IEA, GO:0046872=IEA, GO:0030426=IEA, GO:0046580=IEA, GO:0022617=TAS, GO:0030198=TAS, GO:0043025=IEA, GO:0034097=IEA, GO:0009986=IEA, GO:0042493=IEA, GO:0071310=IEA, GO:0032487=IEA, GO:0007568=IEA, GO:0045762=IEA, GO:0005576=TAS, GO:0007417=IEA, GO:0005604=IEA, GO:0045861=IEA, GO:0005178=IEA, GO:0045666=IEA, GO:0045930=IEA, GO:0008191=IEA, GO:0008047=IEA, GO:0043410=IEA} aging, cellular response to organic substance, central nervous system development, extracellular matrix disassembly, extracellular matrix organization, negative regulation of Ras protein signal transduction, negative regulation of cell proliferation, negative regulation of mitotic cell cycle, negative regulation of proteolysis, positive regulation of MAPK cascade, positive regulation of adenylate cyclase activity, positive regulation of neuron differentiation, regulation of Rap protein signal transduction, response to cytokine stimulus, response to drug basement membrane, cell surface, extracellular region, extracellular space, growth cone, neuronal cell body enzyme activator activity, integrin binding, metal ion binding, metalloendopeptidase inhibitor activity Human TIMP3 BHF-UCL UniProtKB {GO:0005515=PMID:18638486, GO:0051045=PMID:18383040, GO:0071310=GO_REF:0000019, GO:0007601=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0005604=GO_REF:0000019} P35625 Metalloproteinase inhibitor 3 protein 20081121 {GO:0005515=IPI, GO:0051045=IMP, GO:0071310=IEA, GO:0007601=IEA, GO:0046872=IEA, GO:0005604=IEA} cellular response to organic substance, negative regulation of membrane protein ectodomain proteolysis, visual perception basement membrane metal ion binding, protein binding Human TIMP4 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0008191=PMID:8939999, GO:0042493=GO_REF:0000019, GO:0032496=GO_REF:0000019, GO:0043434=GO_REF:0000019, GO:0005576=GO_REF:0000029, GO:0042698=GO_REF:0000019, GO:0034097=GO_REF:0000019, GO:0007417=GO_REF:0000019, GO:0030017=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0046872=GO_REF:0000037} Q99727 Metalloproteinase inhibitor 4 protein 20061026 {GO:0008150=ND, GO:0008191=NAS, GO:0042493=IEA, GO:0032496=IEA, GO:0043434=IEA, GO:0005576=NAS, GO:0042698=IEA, GO:0034097=IEA, GO:0007417=IEA, GO:0030017=IEA, GO:0005615=IEA, GO:0046872=IEA} biological_process, central nervous system development, ovulation cycle, response to cytokine stimulus, response to drug, response to lipopolysaccharide, response to peptide hormone stimulus extracellular region, extracellular space, sarcomere metal ion binding, metalloendopeptidase inhibitor activity Human TINAG PINC UniProtKB {GO:0004197=PMID:10652240, GO:0006955=GO_REF:0000002, GO:0000166=PMID:10652240, GO:0006508=GO_REF:0000002, GO:0030247=GO_REF:0000002, GO:0008234=GO_REF:0000002, GO:0007155=PMID:8770961, GO:0005604=PMID:1762287, GO:0005044=GO_REF:0000002} Q9UJW2 Tubulointerstitial nephritis antigen protein 20050308 {GO:0004197=TAS, GO:0006955=IEA, GO:0000166=TAS, GO:0006508=IEA, GO:0030247=IEA, GO:0008234=IEA, GO:0007155=IDA, GO:0005604=IDA, GO:0005044=IEA} cell adhesion, immune response, proteolysis basement membrane cysteine-type endopeptidase activity, cysteine-type peptidase activity, nucleotide binding, polysaccharide binding, scavenger receptor activity Human TINAGL1 BHF-UCL UniProtKB {GO:0005737=GO_REF:0000019, GO:0006955=GO_REF:0000002, GO:0016197=PMID:10799322, GO:0043236=GO_REF:0000019, GO:0006508=GO_REF:0000002, GO:0005576=PMID:11170462, GO:0030247=GO_REF:0000002, GO:0008234=GO_REF:0000002, GO:0005615=PMID:22261194, GO:0005201=PMID:11170462, GO:0005044=GO_REF:0000002} Q9GZM7 Tubulointerstitial nephritis antigen-like protein 20120228 {GO:0005737=IEA, GO:0006955=IEA, GO:0016197=TAS, GO:0043236=IEA, GO:0006508=IEA, GO:0005576=NAS, GO:0030247=IEA, GO:0008234=IEA, GO:0005615=ISS, GO:0005201=NAS, GO:0005044=IEA} endosomal transport, immune response, proteolysis cytoplasm, extracellular region, extracellular space cysteine-type peptidase activity, extracellular matrix structural constituent, laminin binding, polysaccharide binding, scavenger receptor activity Human UniProtKB:F1SVA2 TINF2 BHF-UCL UniProtKB {GO:0034502=PMID:15380063, GO:0005515=PMID:15380063, GO:0000781=PMID:15380063, GO:0042162=PMID:12768206, GO:0010836=PMID:15133513, GO:0050680=PMID:15741234, GO:0010833=PMID:18669893, GO:0003677=PMID:10581025, GO:0016363=GO_REF:0000039, GO:0032211=PMID:10581025, GO:0000723=Reactome:REACT_7970, GO:0032205=GO_REF:0000019, GO:0005654=Reactome:REACT_8031, GO:0010370=PMID:15741234, GO:0032206=PMID:18443218, GO:0070198=PMID:18443218, GO:0000783=PMID:16880378, GO:0032202=PMID:16880378} Q9BSI4 TERF1-interacting nuclear factor 2 protein 20081205 {GO:0034502=IC, GO:0005515=IPI, GO:0000781=IDA, GO:0042162=IDA, GO:0010836=IGI, GO:0050680=IMP, GO:0010833=IMP, GO:0003677=IDA, GO:0016363=IEA, GO:0032211=IGI, GO:0000723=TAS, GO:0032205=IEA, GO:0005654=TAS, GO:0010370=IDA, GO:0032206=IMP, GO:0070198=IMP, GO:0000783=IDA, GO:0032202=IMP} negative regulation of epithelial cell proliferation, negative regulation of protein ADP-ribosylation, negative regulation of telomere maintenance, negative regulation of telomere maintenance via telomerase, positive regulation of telomere maintenance, protein localization to chromosome, protein localization to chromosome, telomeric region, telomere assembly, telomere maintenance, telomere maintenance via telomere lengthening chromosome, telomeric region, nuclear matrix, nuclear telomere cap complex, nucleoplasm, perinucleolar chromocenter DNA binding, protein binding, telomeric DNA binding Human GO:0008022 TIPARP ENSEMBL UniProtKB {GO:0030097=GO_REF:0000019, GO:0006807=GO_REF:0000019, GO:0001822=GO_REF:0000019, GO:0008209=GO_REF:0000019, GO:0048705=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0009791=GO_REF:0000019, GO:0003950=GO_REF:0000003, GO:0006471=GO_REF:0000019, GO:0008210=GO_REF:0000019, GO:0008585=GO_REF:0000019, GO:0060325=GO_REF:0000019, GO:0048745=GO_REF:0000019, GO:0060021=GO_REF:0000019, GO:0044236=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0048008=GO_REF:0000019, GO:0001570=GO_REF:0000019} Q7Z3E1 "TCDD-inducible poly ""ADP-ribose"" polymerase" protein 20130413 {GO:0030097=IEA, GO:0006807=IEA, GO:0001822=IEA, GO:0008209=IEA, GO:0048705=IEA, GO:0003676=IEA, GO:0009791=IEA, GO:0003950=IEA, GO:0006471=IEA, GO:0008210=IEA, GO:0008585=IEA, GO:0060325=IEA, GO:0048745=IEA, GO:0060021=IEA, GO:0044236=IEA, GO:0008270=IEA, GO:0048008=IEA, GO:0001570=IEA} androgen metabolic process, estrogen metabolic process, face morphogenesis, female gonad development, hemopoiesis, kidney development, multicellular organismal metabolic process, nitrogen compound metabolic process, palate development, platelet-derived growth factor receptor signaling pathway, post-embryonic development, protein ADP-ribosylation, skeletal system morphogenesis, smooth muscle tissue development, vasculogenesis NAD+ ADP-ribosyltransferase activity, nucleic acid binding, zinc ion binding Human Ensembl:ENSMUSP00000048051 TIPIN HPA UniProtKB {GO:0005515=PMID:17102137, GO:0008284=PMID:17102137, GO:0000790=PMID:17102137, GO:0005794=GO_REF:0000052, GO:0033262=PMID:17102137, GO:0033261=PMID:17102137, GO:0048478=GO_REF:0000002, GO:0031573=PMID:17102137, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006974=GO_REF:0000002, GO:0043231=GO_REF:0000052, GO:0007049=GO_REF:0000002, GO:0007067=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0000076=PMID:17102137, GO:0000077=GO_REF:0000019, GO:0009411=GO_REF:0000019, GO:0051301=GO_REF:0000037} Q9BVW5 TIMELESS-interacting protein protein 20111111 {GO:0005515=IPI, GO:0008284=IMP, GO:0000790=IDA, GO:0005794=IDA, GO:0033262=TAS, GO:0033261=IMP, GO:0048478=IEA, GO:0031573=IMP, GO:0005730=IDA, GO:0005634=IDA, GO:0006974=IEA, GO:0043231=IDA, GO:0007049=IEA, GO:0007067=IEA, GO:0005737=IDA, GO:0000076=IMP, GO:0000077=IEA, GO:0009411=IEA, GO:0051301=IEA} DNA damage checkpoint, DNA replication checkpoint, cell cycle, cell division, intra-S DNA damage checkpoint, mitosis, positive regulation of cell proliferation, regulation of DNA replication involved in S phase, regulation of S phase, replication fork protection, response to DNA damage stimulus, response to UV Golgi apparatus, cytoplasm, intracellular membrane-bounded organelle, nuclear chromatin, nucleolus, nucleus protein binding Human TIPRL IntAct UniProtKB {GO:0005515=PMID:16085932, GO:0005737=GO_REF:0000039, GO:0000077=PMID:17384681, GO:0034048=PMID:17384681} O75663 TIP41-like protein protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0000077=IMP, GO:0034048=IDA} DNA damage checkpoint, negative regulation of protein phosphatase type 2A activity cytoplasm protein binding Human UniProtKB:P60510 TIRAP BHF-UCL UniProtKB {GO:0005515=PMID:19509286, GO:0050830=GO_REF:0000024, GO:0007249=GO_REF:0000019, GO:0046330=PMID:11544529, GO:0042803=GO_REF:0000024, GO:0032757=PMID:16301656, GO:0032648=GO_REF:0000024, GO:0002755=PMID:19509286, GO:0005080=PMID:17161867, GO:0032496=PMID:11544529, GO:0030099=GO_REF:0000024, GO:0070374=PMID:11544529, GO:0044130=GO_REF:0000024, GO:0043123=PMID:19509286, GO:0030674=PMID:19509286, GO:0045410=PMID:16301656, GO:0038124=Reactome:REACT_8006, GO:0032760=PMID:16301656, GO:0038123=Reactome:REACT_8005, GO:0046982=PMID:19509286, GO:0034134=Reactome:REACT_7980, GO:0005546=GO_REF:0000024, GO:0002224=Reactome:REACT_6966, GO:0045087=Reactome:REACT_6802, GO:0045088=PMID:11544529, GO:0090023=GO_REF:0000024, GO:0035665=PMID:11544529, GO:0035663=PMID:19509286, GO:0034145=PMID:19509286, GO:0035662=PMID:19509286, GO:0034142=Reactome:REACT_6894, GO:0005886=Reactome:REACT_121298, GO:0034141=GO_REF:0000024, GO:0030890=GO_REF:0000024, GO:0032738=PMID:18583567, GO:0030139=GO_REF:0000024, GO:0032735=GO_REF:0000024, GO:0005829=Reactome:REACT_150418, GO:2000340=GO_REF:0000024, GO:0005737=PMID:19948740, GO:0051092=PMID:19509286, GO:0006954=GO_REF:0000037, GO:0034137=PMID:19509286, GO:0090073=PMID:12062447, GO:0032587=GO_REF:0000024, GO:2000343=GO_REF:0000024, GO:0071221=GO_REF:0000024, GO:0071223=GO_REF:0000024, GO:0070935=PMID:15294994, GO:0007166=GO_REF:0000024} P58753 Toll/interleukin-1 receptor domain-containing adapter protein protein 20110127 {GO:0005515=IPI, GO:0050830=ISS, GO:0007249=IEA, GO:0046330=IMP, GO:0042803=ISS, GO:0032757=IMP, GO:0032648=ISS, GO:0002755=TAS, GO:0005080=IPI, GO:0032496=IDA, GO:0030099=ISS, GO:0070374=IMP, GO:0044130=ISS, GO:0043123=IMP, GO:0030674=NAS, GO:0045410=IMP, GO:0038124=TAS, GO:0032760=IMP, GO:0038123=TAS, GO:0046982=IDA, GO:0034134=TAS, GO:0005546=ISS, GO:0002224=TAS, GO:0045087=TAS, GO:0045088=IC, GO:0090023=ISS, GO:0035665=IDA, GO:0035663=IPI, GO:0034145=IMP, GO:0035662=IPI, GO:0034142=TAS, GO:0005886=TAS, GO:0034141=ISS, GO:0030890=ISS, GO:0032738=IDA, GO:0030139=ISS, GO:0032735=ISS, GO:0005829=TAS, GO:2000340=ISS, GO:0005737=IDA, GO:0051092=IMP, GO:0006954=IEA, GO:0034137=IMP, GO:0090073=IDA, GO:0032587=ISS, GO:2000343=ISS, GO:0071221=ISS, GO:0071223=ISS, GO:0070935=IDA, GO:0007166=ISS} 3'-UTR-mediated mRNA stabilization, I-kappaB kinase/NF-kappaB cascade, MyD88-dependent toll-like receptor signaling pathway, TIRAP-dependent toll-like receptor 4 signaling pathway, cell surface receptor signaling pathway, cellular response to bacterial lipopeptide, cellular response to lipoteichoic acid, defense response to Gram-positive bacterium, inflammatory response, innate immune response, myeloid cell differentiation, negative regulation of growth of symbiont in host, positive regulation of B cell proliferation, positive regulation of ERK1 and ERK2 cascade, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of JNK cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of chemokine (C-X-C motif) ligand 1 production, positive regulation of chemokine (C-X-C motif) ligand 2 production, positive regulation of interleukin-12 production, positive regulation of interleukin-15 production, positive regulation of interleukin-6 biosynthetic process, positive regulation of interleukin-8 production, positive regulation of neutrophil chemotaxis, positive regulation of protein homodimerization activity, positive regulation of toll-like receptor 2 signaling pathway, positive regulation of toll-like receptor 3 signaling pathway, positive regulation of toll-like receptor 4 signaling pathway, positive regulation of tumor necrosis factor production, regulation of innate immune response, regulation of interferon-beta production, response to lipopolysaccharide, toll-like receptor 2 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway cytoplasm, cytosol, endocytic vesicle, plasma membrane, ruffle membrane Toll-like receptor 2 binding, Toll-like receptor 4 binding, phosphatidylinositol-4,5-bisphosphate binding, protein binding, protein binding, bridging, protein heterodimerization activity, protein homodimerization activity, protein kinase C binding Human TJAP1 HPA UniProtKB {GO:0005515=PMID:15263016, GO:0005794=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005923=GO_REF:0000039} Q5JTD0 Tight junction-associated protein 1 protein 20110516 {GO:0005515=IPI, GO:0005794=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0005923=IEA} Golgi apparatus, nucleolus, nucleus, tight junction protein binding Human TJP1 HPA UniProtKB {GO:0005515=PMID:16944923, GO:0005516=GO_REF:0000037, GO:0030054=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0045471=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_118750, GO:0016323=PMID:16427635, GO:0043296=PMID:16427635, GO:0005737=GO_REF:0000052, GO:0046581=GO_REF:0000019, GO:0005913=GO_REF:0000019, GO:0014704=GO_REF:0000019, GO:1901350=PMID:8395056, GO:0032496=GO_REF:0000019, GO:0071333=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0001825=GO_REF:0000019, GO:0006915=Reactome:REACT_578, GO:0045177=PMID:22006950, GO:0035329=Reactome:REACT_118607, GO:0008022=GO_REF:0000019, GO:0071000=GO_REF:0000019, GO:0016327=GO_REF:0000019, GO:0007043=PMID:8486731, GO:0005921=GO_REF:0000039, GO:0005923=PMID:22006950, GO:0043116=GO_REF:0000019} Q07157 Tight junction protein ZO-1 protein 20120912 {GO:0005515=IPI, GO:0005516=IEA, GO:0030054=IDA, GO:0005886=IDA, GO:0045471=IEA, GO:0005634=IEA, GO:0006921=TAS, GO:0005829=TAS, GO:0016323=IDA, GO:0043296=IDA, GO:0005737=IDA, GO:0046581=IEA, GO:0005913=IEA, GO:0014704=IEA, GO:1901350=NAS, GO:0032496=IEA, GO:0071333=IEA, GO:0042493=IEA, GO:0019904=IEA, GO:0001825=IEA, GO:0006915=TAS, GO:0045177=IDA, GO:0035329=TAS, GO:0008022=IEA, GO:0071000=IEA, GO:0016327=IEA, GO:0007043=TAS, GO:0005921=IEA, GO:0005923=IDA, GO:0043116=IEA} apoptotic process, blastocyst formation, cell-cell junction assembly, cell-cell signaling involved in cell-cell junction organization, cellular component disassembly involved in execution phase of apoptosis, cellular response to glucose stimulus, hippo signaling cascade, negative regulation of vascular permeability, response to drug, response to ethanol, response to lipopolysaccharide, response to magnetism apical junction complex, apical part of cell, apicolateral plasma membrane, basolateral plasma membrane, cell junction, cell-cell adherens junction, cytoplasm, cytosol, gap junction, intercalated disc, intercellular canaliculus, nucleus, plasma membrane, tight junction calmodulin binding, protein C-terminus binding, protein binding, protein domain specific binding Human TJP2 HPA UniProtKB {GO:0005515=PMID:18823282, GO:0005737=GO_REF:0000052, GO:0030054=GO_REF:0000052, GO:0005912=GO_REF:0000039, GO:0005886=GO_REF:0000052, GO:0006915=Reactome:REACT_578, GO:0004385=PMID:8824195, GO:0005654=Reactome:REACT_118822, GO:0035329=Reactome:REACT_118607, GO:0005923=PMID:22006950, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_118825} Q9UDY2 Tight junction protein ZO-2 protein 20080205 {GO:0005515=IPI, GO:0005737=IDA, GO:0030054=IDA, GO:0005912=IEA, GO:0005886=IDA, GO:0006915=TAS, GO:0004385=TAS, GO:0005654=TAS, GO:0035329=TAS, GO:0005923=IDA, GO:0006921=TAS, GO:0005829=TAS} apoptotic process, cellular component disassembly involved in execution phase of apoptosis, hippo signaling cascade adherens junction, cell junction, cytoplasm, cytosol, nucleoplasm, plasma membrane, tight junction guanylate kinase activity, protein binding Human TJP3 UniProtKB UniProtKB {GO:0005515=PMID:18823282, GO:0016324=GO_REF:0000019, GO:0005634=PMID:18823282, GO:0005923=PMID:18823282, GO:2000045=GO_REF:0000019} O95049 Tight junction protein ZO-3 protein 20120720 {GO:0005515=IPI, GO:0016324=IEA, GO:0005634=IDA, GO:0005923=IDA, GO:2000045=IEA} regulation of G1/S transition of mitotic cell cycle apical plasma membrane, nucleus, tight junction protein binding Human TK1 GOC UniProtKB {GO:0009636=GO_REF:0000019, GO:0046104=GO_REF:0000019, GO:0055086=Reactome:REACT_1698, GO:0048565=GO_REF:0000019, GO:0060138=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0043097=Reactome:REACT_655, GO:0019206=Reactome:REACT_437, GO:0005524=GO_REF:0000037, GO:0009165=Reactome:REACT_437, GO:0005829=Reactome:REACT_437, GO:0051414=GO_REF:0000019, GO:0006260=GO_REF:0000037, GO:0001889=GO_REF:0000019, GO:0006139=PMID:3335503, GO:0051289=PMID:17407781, GO:0014856=GO_REF:0000019, GO:0031667=GO_REF:0000019, GO:0008270=PMID:17407781, GO:0046688=GO_REF:0000019, GO:0006206=Reactome:REACT_957, GO:0004797=GO_REF:0000003} P04183 Thymidine kinase, cytosolic protein 20130413 {GO:0009636=IEA, GO:0046104=IEA, GO:0055086=TAS, GO:0048565=IEA, GO:0060138=IEA, GO:0044281=TAS, GO:0043097=TAS, GO:0019206=EXP, GO:0005524=IEA, GO:0009165=EXP, GO:0005829=TAS, GO:0051414=IEA, GO:0006260=IEA, GO:0001889=IEA, GO:0006139=TAS, GO:0051289=IPI, GO:0014856=IEA, GO:0031667=IEA, GO:0008270=IDA, GO:0046688=IEA, GO:0006206=TAS, GO:0004797=IEA} DNA replication, digestive tract development, fetal process involved in parturition, liver development, nucleobase-containing compound metabolic process, nucleobase-containing small molecule metabolic process, nucleotide biosynthetic process, protein homotetramerization, pyrimidine nucleobase metabolic process, pyrimidine nucleoside salvage, response to copper ion, response to cortisol stimulus, response to nutrient levels, response to toxic substance, skeletal muscle cell proliferation, small molecule metabolic process, thymidine metabolic process cytosol ATP binding, nucleoside kinase activity, thymidine kinase activity, zinc ion binding Human TK2 Reactome UniProtKB {GO:0046092=GO_REF:0000019, GO:0005743=GO_REF:0000019, GO:0046104=GO_REF:0000019, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0043097=Reactome:REACT_655, GO:0005524=GO_REF:0000037, GO:0006139=PMID:9079672, GO:0009262=GO_REF:0000019, GO:0016301=GO_REF:0000038, GO:0005759=Reactome:REACT_1691, GO:0016773=GO_REF:0000002, GO:0004137=GO_REF:0000019, GO:0006264=GO_REF:0000019, GO:0006206=Reactome:REACT_957, GO:0004797=GO_REF:0000003} O00142 Thymidine kinase 2, mitochondrial protein 20130301 {GO:0046092=IEA, GO:0005743=IEA, GO:0046104=IEA, GO:0055086=TAS, GO:0044281=TAS, GO:0043097=TAS, GO:0005524=IEA, GO:0006139=TAS, GO:0009262=IEA, GO:0016301=IEA, GO:0005759=TAS, GO:0016773=IEA, GO:0004137=IEA, GO:0006264=IEA, GO:0006206=TAS, GO:0004797=IEA} deoxycytidine metabolic process, deoxyribonucleotide metabolic process, mitochondrial DNA replication, nucleobase-containing compound metabolic process, nucleobase-containing small molecule metabolic process, pyrimidine nucleobase metabolic process, pyrimidine nucleoside salvage, small molecule metabolic process, thymidine metabolic process mitochondrial inner membrane, mitochondrial matrix ATP binding, deoxycytidine kinase activity, kinase activity, phosphotransferase activity, alcohol group as acceptor, thymidine kinase activity Human TKT HPA UniProtKB {GO:0005999=Reactome:REACT_939, GO:0005975=Reactome:REACT_474, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0006098=Reactome:REACT_1859, GO:0046166=PMID:9611778, GO:0046872=GO_REF:0000037, GO:0009052=PMID:9357955, GO:0042803=PMID:20667822, GO:0004802=Reactome:REACT_1811, GO:0005829=Reactome:REACT_1811, GO:0006112=Reactome:REACT_1505, GO:0040008=GO_REF:0000019, GO:0005777=GO_REF:0000024} P29401 Transketolase protein 20111111 {GO:0005999=TAS, GO:0005975=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0006098=TAS, GO:0046166=IDA, GO:0046872=IEA, GO:0009052=NAS, GO:0042803=IDA, GO:0004802=EXP, GO:0005829=TAS, GO:0006112=TAS, GO:0040008=IEA, GO:0005777=ISS} carbohydrate metabolic process, energy reserve metabolic process, glyceraldehyde-3-phosphate biosynthetic process, pentose-phosphate shunt, pentose-phosphate shunt, non-oxidative branch, regulation of growth, small molecule metabolic process, xylulose biosynthetic process cytosol, nucleolus, nucleus, peroxisome metal ion binding, protein homodimerization activity, transketolase activity NOT Human TKTL2 LIFEdb UniProtKB {GO:0005737=GO_REF:0000054, GO:0046872=GO_REF:0000037, GO:0004802=GO_REF:0000003} Q9H0I9 Transketolase-like protein 2 protein 20100607 {GO:0005737=IDA, GO:0046872=IEA, GO:0004802=IEA} cytoplasm metal ion binding, transketolase activity Human TLCD1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q96CP7 TLC domain-containing protein 1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TLE1 BHF-UCL UniProtKB {GO:0005515=PMID:10748198, GO:0005667=GO_REF:0000019, GO:0001106=PMID:10748198, GO:0030178=PMID:9751710, GO:0005634=PMID:10748198, GO:0007275=PMID:8365415, GO:2000811=PMID:22952044, GO:0007165=PMID:8808280, GO:0007219=Reactome:REACT_118859, GO:0003682=GO_REF:0000019, GO:0009887=PMID:8808280, GO:0005654=Reactome:REACT_118605, GO:0016055=GO_REF:0000037, GO:0045892=PMID:9751710, GO:0008134=PMID:8687460, GO:0043124=PMID:17680780} Q04724 Transducin-like enhancer protein 1 protein 20110802 {GO:0005515=IPI, GO:0005667=IEA, GO:0001106=IDA, GO:0030178=NAS, GO:0005634=IDA, GO:0007275=TAS, GO:2000811=IMP, GO:0007165=TAS, GO:0007219=TAS, GO:0003682=IEA, GO:0009887=TAS, GO:0005654=TAS, GO:0016055=IEA, GO:0045892=IDA, GO:0008134=IPI, GO:0043124=IDA} Notch signaling pathway, Wnt receptor signaling pathway, multicellular organismal development, negative regulation of I-kappaB kinase/NF-kappaB cascade, negative regulation of Wnt receptor signaling pathway, negative regulation of anoikis, negative regulation of transcription, DNA-dependent, organ morphogenesis, signal transduction nucleoplasm, nucleus, transcription factor complex RNA polymerase II transcription corepressor activity, chromatin binding, protein binding, transcription factor binding Human TLE2 IntAct UniProtKB {GO:0005515=PMID:17041588, GO:0007165=PMID:8808280, GO:0006355=GO_REF:0000002, GO:0007219=Reactome:REACT_118859, GO:0003714=PMID:19460168, GO:0009887=PMID:8808280, GO:0005654=Reactome:REACT_118605, GO:0005634=PMID:1303260, GO:0016055=GO_REF:0000037, GO:0090090=PMID:19460168, GO:0045892=PMID:19460168, GO:0006351=GO_REF:0000037} Q04725 Transducin-like enhancer protein 2 protein 20130415 {GO:0005515=IPI, GO:0007165=TAS, GO:0006355=IEA, GO:0007219=TAS, GO:0003714=IDA, GO:0009887=TAS, GO:0005654=TAS, GO:0005634=TAS, GO:0016055=IEA, GO:0090090=IDA, GO:0045892=IDA, GO:0006351=IEA} Notch signaling pathway, Wnt receptor signaling pathway, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of transcription, DNA-dependent, organ morphogenesis, regulation of transcription, DNA-dependent, signal transduction, transcription, DNA-dependent nucleoplasm, nucleus protein binding, transcription corepressor activity Human UniProtKB:Q16531 TLE3 InterPro UniProtKB {GO:0005515=PMID:22304967, GO:0007165=PMID:8808280, GO:0006355=GO_REF:0000002, GO:0007219=Reactome:REACT_118859, GO:0009887=PMID:8808280, GO:0005654=Reactome:REACT_118605, GO:0005634=GO_REF:0000002, GO:0016055=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6PI57 Transducin-like enhancer protein 3 protein 20130413 {GO:0005515=IPI, GO:0007165=TAS, GO:0006355=IEA, GO:0007219=TAS, GO:0009887=TAS, GO:0005654=TAS, GO:0005634=IEA, GO:0016055=IEA, GO:0006351=IEA} Notch signaling pathway, Wnt receptor signaling pathway, organ morphogenesis, regulation of transcription, DNA-dependent, signal transduction, transcription, DNA-dependent nucleoplasm, nucleus protein binding Human InterPro:IPR009146 TLE4 Reactome UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0006355=GO_REF:0000002, GO:0007219=Reactome:REACT_118859, GO:0003714=GO_REF:0000019, GO:0003705=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0070491=GO_REF:0000019, GO:0005654=Reactome:REACT_118605, GO:0005634=PMID:1303260, GO:0000122=GO_REF:0000019, GO:0016055=GO_REF:0000019} Q04727 Transducin-like enhancer protein 4 protein 20130301 {GO:0003674=ND, GO:0008150=ND, GO:0006355=IEA, GO:0007219=TAS, GO:0003714=IEA, GO:0003705=IEA, GO:0003682=IEA, GO:0070491=IEA, GO:0005654=TAS, GO:0005634=NAS, GO:0000122=IEA, GO:0016055=IEA} Notch signaling pathway, Wnt receptor signaling pathway, biological_process, negative regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent nucleoplasm, nucleus RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, chromatin binding, molecular_function, repressing transcription factor binding, transcription corepressor activity Human TLE6 UniProtKB UniProtKB {GO:0043234=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0006355=GO_REF:0000002, GO:0005634=GO_REF:0000002, GO:0005938=GO_REF:0000019} Q9H808 Transducin-like enhancer protein 6 protein 20130413 {GO:0043234=IEA, GO:0005737=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0005938=IEA} regulation of transcription, DNA-dependent cell cortex, cytoplasm, nucleus, protein complex Human UniProtKB-SubCell:SL-0086 TLK1 HPA UniProtKB {GO:0035556=PMID:12660173, GO:0007049=GO_REF:0000037, GO:0004674=PMID:12660173, GO:0006468=PMID:12660173, GO:0005634=GO_REF:0000052, GO:0001672=PMID:12660173, GO:0006886=PMID:10588641, GO:0005524=PMID:12660173, GO:0006974=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q9UKI8 Serine/threonine-protein kinase tousled-like 1 protein 20090616 {GO:0035556=IDA, GO:0007049=IEA, GO:0004674=IDA, GO:0006468=IDA, GO:0005634=IDA, GO:0001672=IDA, GO:0006886=IDA, GO:0005524=IDA, GO:0006974=IEA, GO:0016568=IEA} cell cycle, chromatin modification, intracellular protein transport, intracellular signal transduction, protein phosphorylation, regulation of chromatin assembly or disassembly, response to DNA damage stimulus nucleus ATP binding, protein serine/threonine kinase activity Human TLK2 BHF-UCL UniProtKB {GO:0005515=PMID:21903422, GO:0005882=PMID:10455159, GO:0048471=PMID:10455159, GO:0005634=PMID:10455159, GO:0071480=PMID:12660173, GO:0032435=PMID:20016786, GO:0005524=PMID:12660173, GO:0006974=PMID:12660173, GO:0035556=PMID:12660173, GO:0007049=GO_REF:0000037, GO:0007059=PMID:20705056, GO:0018105=PMID:20016786, GO:0004674=PMID:12660173, GO:0010507=PMID:22354037, GO:0006468=PMID:12660173, GO:0001672=PMID:12660173, GO:0016568=GO_REF:0000037} Q86UE8 Serine/threonine-protein kinase tousled-like 2 protein 20120531 {GO:0005515=IPI, GO:0005882=IDA, GO:0048471=IDA, GO:0005634=IDA, GO:0071480=IDA, GO:0032435=IMP, GO:0005524=IDA, GO:0006974=IDA, GO:0035556=IDA, GO:0007049=IEA, GO:0007059=IMP, GO:0018105=IDA, GO:0004674=IDA, GO:0010507=NAS, GO:0006468=IDA, GO:0001672=IDA, GO:0016568=IEA} cell cycle, cellular response to gamma radiation, chromatin modification, chromosome segregation, intracellular signal transduction, negative regulation of autophagy, negative regulation of proteasomal ubiquitin-dependent protein catabolic process, peptidyl-serine phosphorylation, protein phosphorylation, regulation of chromatin assembly or disassembly, response to DNA damage stimulus intermediate filament, nucleus, perinuclear region of cytoplasm ATP binding, protein binding, protein serine/threonine kinase activity Human TLL1 Reactome UniProtKB {GO:0001501=PMID:8661043, GO:0030198=Reactome:REACT_118779, GO:0005509=GO_REF:0000002, GO:0005518=GO_REF:0000019, GO:0006508=GO_REF:0000037, GO:0005576=Reactome:REACT_150462, GO:0008270=GO_REF:0000002, GO:0004222=GO_REF:0000002, GO:0030154=GO_REF:0000037} O43897 Tolloid-like protein 1 protein 20130301 {GO:0001501=TAS, GO:0030198=TAS, GO:0005509=IEA, GO:0005518=IEA, GO:0006508=IEA, GO:0005576=TAS, GO:0008270=IEA, GO:0004222=IEA, GO:0030154=IEA} cell differentiation, extracellular matrix organization, proteolysis, skeletal system development extracellular region calcium ion binding, collagen binding, metalloendopeptidase activity, zinc ion binding Human TLN1 HPA UniProtKB {GO:0005515=PMID:19608030, GO:0005886=GO_REF:0000052, GO:0005158=GO_REF:0000002, GO:0006928=PMID:10610730, GO:0015629=GO_REF:0000002, GO:0043231=GO_REF:0000052, GO:0030968=Reactome:REACT_18356, GO:0005829=Reactome:REACT_115665, GO:0006936=Reactome:REACT_20558, GO:0007411=Reactome:REACT_18266, GO:0005911=PMID:15494027, GO:0030274=PMID:10320340, GO:0007155=GO_REF:0000002, GO:0007016=PMID:10610730, GO:0005813=GO_REF:0000052, GO:0030168=Reactome:REACT_798, GO:0032587=GO_REF:0000039, GO:0003779=GO_REF:0000002, GO:0005576=Reactome:REACT_21347, GO:0001726=GO_REF:0000024, GO:0007596=Reactome:REACT_604, GO:0030866=GO_REF:0000019, GO:0017166=PMID:15070891, GO:0002576=Reactome:REACT_318, GO:0005200=PMID:10610730, GO:0007043=PMID:15494027, GO:0007044=GO_REF:0000019, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0005925=GO_REF:0000052} Q9Y490 Talin-1 protein 20101115 {GO:0005515=IPI, GO:0005886=IDA, GO:0005158=IEA, GO:0006928=NAS, GO:0015629=IEA, GO:0043231=IDA, GO:0030968=TAS, GO:0005829=TAS, GO:0006936=TAS, GO:0007411=TAS, GO:0005911=IC, GO:0030274=IPI, GO:0007155=IEA, GO:0007016=NAS, GO:0005813=IDA, GO:0030168=TAS, GO:0032587=IEA, GO:0003779=IEA, GO:0005576=TAS, GO:0001726=ISS, GO:0007596=TAS, GO:0030866=IEA, GO:0017166=IPI, GO:0002576=TAS, GO:0005200=NAS, GO:0007043=TAS, GO:0007044=IEA, GO:0006987=TAS, GO:0044267=TAS, GO:0005925=IDA} activation of signaling protein activity involved in unfolded protein response, axon guidance, blood coagulation, cell adhesion, cell-cell junction assembly, cell-substrate junction assembly, cellular component movement, cellular protein metabolic process, cortical actin cytoskeleton organization, cytoskeletal anchoring at plasma membrane, endoplasmic reticulum unfolded protein response, muscle contraction, platelet activation, platelet degranulation actin cytoskeleton, cell-cell junction, centrosome, cytosol, extracellular region, focal adhesion, intracellular membrane-bounded organelle, plasma membrane, ruffle, ruffle membrane LIM domain binding, actin binding, insulin receptor binding, protein binding, structural constituent of cytoskeleton, vinculin binding Human TLN2 UniProtKB UniProtKB {GO:0005515=PMID:10320934, GO:0005886=GO_REF:0000039, GO:0005158=GO_REF:0000002, GO:0045202=PMID:11907066, GO:0003779=PMID:10320934, GO:0015629=PMID:10320934, GO:0001726=GO_REF:0000002, GO:0005916=GO_REF:0000019, GO:0005737=GO_REF:0000037, GO:0005911=PMID:15494027, GO:0005198=PMID:10320934, GO:0007043=PMID:15494027, GO:0005200=GO_REF:0000002, GO:0007155=PMID:11907066, GO:0007016=GO_REF:0000002, GO:0005925=GO_REF:0000039} Q9Y4G6 Talin-2 protein 20061120 {GO:0005515=IPI, GO:0005886=IEA, GO:0005158=IEA, GO:0045202=NAS, GO:0003779=NAS, GO:0015629=NAS, GO:0001726=IEA, GO:0005916=IEA, GO:0005737=IEA, GO:0005911=IC, GO:0005198=NAS, GO:0007043=TAS, GO:0005200=IEA, GO:0007155=NAS, GO:0007016=IEA, GO:0005925=IEA} cell adhesion, cell-cell junction assembly, cytoskeletal anchoring at plasma membrane actin cytoskeleton, cell-cell junction, cytoplasm, fascia adherens, focal adhesion, plasma membrane, ruffle, synapse actin binding, insulin receptor binding, protein binding, structural constituent of cytoskeleton, structural molecule activity Human UniProtKB:P18206 TLR1 MGI UniProtKB {GO:0005886=PMID:9435236, GO:0042088=GO_REF:0000002, GO:0006955=PMID:10426995, GO:0006954=GO_REF:0000037, GO:0002755=GO_REF:0000002, GO:0042495=PMID:19931471, GO:0042496=GO_REF:0000002, GO:0030670=GO_REF:0000039, GO:0004872=PMID:10426995, GO:0045410=PMID:12077222, GO:0034130=GO_REF:0000002, GO:0034150=GO_REF:0000002, GO:0046982=PMID:17889651, GO:0042535=PMID:12077222, GO:0006952=GO_REF:0000019, GO:0007165=PMID:9435236, GO:0016020=PMID:11081518, GO:0042116=PMID:11607792, GO:0005887=PMID:9435236, GO:0045087=GO_REF:0000037, GO:0035354=PMID:17889651, GO:0050707=GO_REF:0000002, GO:0016021=GO_REF:0000002, GO:0071727=PMID:19931471, GO:0004888=PMID:11081518} Q15399 Toll-like receptor 1 protein 20101109 {GO:0005886=TAS, GO:0042088=IEA, GO:0006955=TAS, GO:0006954=IEA, GO:0002755=IEA, GO:0042495=IDA, GO:0042496=IEA, GO:0030670=IEA, GO:0004872=TAS, GO:0045410=ISS, GO:0034130=IEA, GO:0034150=IEA, GO:0046982=IDA, GO:0042535=ISS, GO:0006952=IEA, GO:0007165=TAS, GO:0016020=NAS, GO:0042116=NAS, GO:0005887=TAS, GO:0045087=IEA, GO:0035354=IDA, GO:0050707=IEA, GO:0016021=IEA, GO:0071727=IDA, GO:0004888=NAS} MyD88-dependent toll-like receptor signaling pathway, T-helper 1 type immune response, cellular response to triacyl bacterial lipopeptide, defense response, detection of diacyl bacterial lipopeptide, detection of triacyl bacterial lipopeptide, immune response, inflammatory response, innate immune response, macrophage activation, positive regulation of interleukin-6 biosynthetic process, positive regulation of tumor necrosis factor biosynthetic process, regulation of cytokine secretion, signal transduction, toll-like receptor 1 signaling pathway, toll-like receptor 6 signaling pathway Toll-like receptor 1-Toll-like receptor 2 protein complex, integral to membrane, integral to plasma membrane, membrane, phagocytic vesicle membrane, plasma membrane protein heterodimerization activity, receptor activity, transmembrane signaling receptor activity Human TLR10 Reactome UniProtKB {GO:0005886=Reactome:REACT_27293, GO:0002224=Reactome:REACT_6966, GO:0006955=PMID:11267672, GO:0006954=GO_REF:0000037, GO:0016020=PMID:11267672, GO:0002755=Reactome:REACT_27215, GO:0045087=Reactome:REACT_6802, GO:0050729=GO_REF:0000002, GO:0034166=Reactome:REACT_9027, GO:0050707=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0034146=Reactome:REACT_9061, GO:0004888=PMID:11267672} Q9BXR5 Toll-like receptor 10 protein 20080327 {GO:0005886=TAS, GO:0002224=TAS, GO:0006955=NAS, GO:0006954=IEA, GO:0016020=TAS, GO:0002755=TAS, GO:0045087=TAS, GO:0050729=IEA, GO:0034166=TAS, GO:0050707=IEA, GO:0016021=IEA, GO:0034146=TAS, GO:0004888=TAS} MyD88-dependent toll-like receptor signaling pathway, immune response, inflammatory response, innate immune response, positive regulation of inflammatory response, regulation of cytokine secretion, toll-like receptor 10 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor signaling pathway integral to membrane, membrane, plasma membrane transmembrane signaling receptor activity Human TLR2 GOC UniProtKB {GO:0032755=PMID:19740627, GO:0005515=PMID:19509286, GO:0034123=PMID:17128265, GO:0050830=GO_REF:0000019, GO:0032757=PMID:17128265, GO:0042497=PMID:17889651, GO:0042498=GO_REF:0000019, GO:0002752=GO_REF:0000019, GO:0042495=PMID:19931471, GO:0002755=Reactome:REACT_6788, GO:0042496=PMID:19931471, GO:0044130=GO_REF:0000019, GO:0031663=PMID:11518816, GO:0032728=GO_REF:0000024, GO:0071726=PMID:19931471, GO:0038124=Reactome:REACT_8006, GO:0032760=GO_REF:0000024, GO:0009986=PMID:12443841, GO:0046982=PMID:17889651, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0042834=PMID:11986301, GO:0042535=GO_REF:0000019, GO:0032722=PMID:19740627, GO:0002224=Reactome:REACT_6966, GO:0005887=PMID:9435236, GO:0045087=PMID:15356140, GO:0071727=PMID:19931471, GO:0009897=GO_REF:0000019, GO:0004888=GO_REF:0000002, GO:0008329=PMID:10384090, GO:0042346=PMID:19740627, GO:0034142=Reactome:REACT_6894, GO:0070891=GO_REF:0000019, GO:0005886=PMID:19740627, GO:0001875=PMID:11518816, GO:0030177=PMID:16601243, GO:0002238=GO_REF:0000019, GO:0032735=GO_REF:0000024, GO:0050715=GO_REF:0000019, GO:0045429=GO_REF:0000019, GO:0006955=PMID:10426995, GO:0005737=PMID:19740627, GO:0006954=GO_REF:0000037, GO:0051092=PMID:12594207, GO:0045944=GO_REF:0000024, GO:0004872=PMID:11672593, GO:0032741=GO_REF:0000024, GO:0052063=GO_REF:0000019, GO:0007252=PMID:19740627, GO:0006917=PMID:10426996, GO:0032700=GO_REF:0000019, GO:0071221=PMID:15356140, GO:0007165=PMID:11044375, GO:0071223=PMID:12594207, GO:0032695=GO_REF:0000019, GO:0035354=PMID:17889651, GO:0050729=PMID:19740627, GO:0051637=PMID:11521063, GO:0002687=GO_REF:0000019, GO:0035355=GO_REF:0000019, GO:0060907=GO_REF:0000019, GO:0042892=GO_REF:0000019, GO:0051770=GO_REF:0000024, GO:0071224=GO_REF:0000019} O60603 Toll-like receptor 2 protein 20130413 {GO:0032755=IDA, GO:0005515=IPI, GO:0034123=IDA, GO:0050830=IEA, GO:0032757=IDA, GO:0042497=IDA, GO:0042498=IEA, GO:0002752=IEA, GO:0042495=IDA, GO:0002755=TAS, GO:0042496=IDA, GO:0044130=IEA, GO:0031663=TAS, GO:0032728=ISS, GO:0071726=IDA, GO:0038124=TAS, GO:0032760=ISS, GO:0009986=IDA, GO:0046982=IDA, GO:0038123=TAS, GO:0034134=TAS, GO:0042834=IDA, GO:0042535=IEA, GO:0032722=IDA, GO:0002224=TAS, GO:0005887=TAS, GO:0045087=TAS, GO:0071727=IDA, GO:0009897=IEA, GO:0004888=IEA, GO:0008329=IDA, GO:0042346=IDA, GO:0034142=TAS, GO:0070891=IEA, GO:0005886=IDA, GO:0001875=TAS, GO:0030177=IMP, GO:0002238=IEA, GO:0032735=ISS, GO:0050715=IEA, GO:0045429=IEA, GO:0006955=TAS, GO:0005737=IDA, GO:0006954=IEA, GO:0051092=IDA, GO:0045944=ISS, GO:0004872=IDA, GO:0032741=ISS, GO:0052063=IEA, GO:0007252=IDA, GO:0006917=TAS, GO:0032700=IEA, GO:0071221=TAS, GO:0007165=TAS, GO:0071223=IDA, GO:0032695=IEA, GO:0035354=IDA, GO:0050729=IC, GO:0051637=IDA, GO:0002687=IEA, GO:0035355=IEA, GO:0060907=IEA, GO:0042892=IEA, GO:0051770=ISS, GO:0071224=IEA} I-kappaB phosphorylation, MyD88-dependent toll-like receptor signaling pathway, cell surface pattern recognition receptor signaling pathway, cellular response to bacterial lipopeptide, cellular response to diacyl bacterial lipopeptide, cellular response to lipoteichoic acid, cellular response to peptidoglycan, cellular response to triacyl bacterial lipopeptide, chloramphenicol transport, defense response to Gram-positive bacterium, detection of diacyl bacterial lipopeptide, detection of triacyl bacterial lipopeptide, immune response, induction by symbiont of defense-related host nitric oxide production, induction of apoptosis, inflammatory response, innate immune response, lipopolysaccharide-mediated signaling pathway, negative regulation of growth of symbiont in host, negative regulation of interleukin-12 production, negative regulation of interleukin-17 production, positive regulation of NF-kappaB import into nucleus, positive regulation of NF-kappaB transcription factor activity, positive regulation of Wnt receptor signaling pathway, positive regulation of chemokine production, positive regulation of cytokine secretion, positive regulation of inflammatory response, positive regulation of interferon-beta production, positive regulation of interleukin-12 production, positive regulation of interleukin-18 production, positive regulation of interleukin-6 production, positive regulation of interleukin-8 production, positive regulation of leukocyte migration, positive regulation of macrophage cytokine production, positive regulation of nitric oxide biosynthetic process, positive regulation of nitric-oxide synthase biosynthetic process, positive regulation of toll-like receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, positive regulation of tumor necrosis factor biosynthetic process, positive regulation of tumor necrosis factor production, response to molecule of fungal origin, signal transduction, toll-like receptor 2 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway Toll-like receptor 1-Toll-like receptor 2 protein complex, Toll-like receptor 2-Toll-like receptor 6 protein complex, cell surface, cytoplasm, external side of plasma membrane, integral to plasma membrane, plasma membrane Gram-positive bacterial cell surface binding, diacyl lipopeptide binding, lipopolysaccharide receptor activity, lipoteichoic acid binding, pattern recognition receptor activity, peptidoglycan binding, protein binding, protein heterodimerization activity, receptor activity, transmembrane signaling receptor activity, triacyl lipopeptide binding Human TLR3 BHF-UCL UniProtKB {GO:0032755=PMID:19740627, GO:0003725=PMID:16111635, GO:0042346=PMID:19740627, GO:0034142=Reactome:REACT_6894, GO:0034123=PMID:17128265, GO:0007249=Reactome:REACT_25351, GO:0046330=GO_REF:0000019, GO:0032735=GO_REF:0000024, GO:0032757=PMID:17128265, GO:0002756=Reactome:REACT_6809, GO:0005737=PMID:19740627, GO:0051607=PMID:15356140, GO:0051092=GO_REF:0000019, GO:0006954=GO_REF:0000037, GO:0036020=Reactome:REACT_118774, GO:0045078=PMID:16286015, GO:0045944=GO_REF:0000024, GO:0009597=PMID:12054664, GO:0004872=PMID:10426995, GO:0043123=GO_REF:0000019, GO:0034138=Reactome:REACT_6783, GO:0042742=PMID:10426995, GO:0032728=GO_REF:0000024, GO:0032760=GO_REF:0000024, GO:0007250=PMID:12054664, GO:0009986=PMID:19740627, GO:0007252=PMID:19740627, GO:0034346=GO_REF:0000019, GO:0045671=PMID:12133979, GO:0032722=PMID:19740627, GO:0002224=Reactome:REACT_6966, GO:0006972=PMID:12054664, GO:0007165=PMID:9435236, GO:0045359=PMID:12054664, GO:0000139=Reactome:REACT_118791, GO:0016020=PMID:12054664, GO:0005887=PMID:9435236, GO:0045087=PMID:15356140, GO:0045356=PMID:16286015, GO:0050729=PMID:19740627, GO:0005789=Reactome:REACT_118802, GO:0035666=Reactome:REACT_25281, GO:0016021=GO_REF:0000038, GO:0071260=PMID:19593445, GO:0043330=GO_REF:0000019, GO:0010008=Reactome:REACT_150447, GO:0004888=PMID:12054664, GO:0045080=GO_REF:0000019} O15455 Toll-like receptor 3 protein 20100304 {GO:0032755=IDA, GO:0003725=IDA, GO:0042346=IDA, GO:0034142=TAS, GO:0034123=IDA, GO:0007249=TAS, GO:0046330=IEA, GO:0032735=ISS, GO:0032757=IDA, GO:0002756=TAS, GO:0005737=IDA, GO:0051607=TAS, GO:0051092=IEA, GO:0006954=IEA, GO:0036020=TAS, GO:0045078=IDA, GO:0045944=ISS, GO:0009597=NAS, GO:0004872=TAS, GO:0043123=IEA, GO:0034138=TAS, GO:0042742=TAS, GO:0032728=ISS, GO:0032760=ISS, GO:0007250=NAS, GO:0009986=IDA, GO:0007252=IDA, GO:0034346=IEA, GO:0045671=NAS, GO:0032722=IDA, GO:0002224=TAS, GO:0006972=NAS, GO:0007165=TAS, GO:0045359=IMP, GO:0000139=TAS, GO:0016020=NAS, GO:0005887=TAS, GO:0045087=TAS, GO:0045356=IDA, GO:0050729=IC, GO:0005789=TAS, GO:0035666=TAS, GO:0016021=IEA, GO:0071260=IEP, GO:0043330=IEA, GO:0010008=TAS, GO:0004888=NAS, GO:0045080=IEA} I-kappaB kinase/NF-kappaB cascade, I-kappaB phosphorylation, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, activation of NF-kappaB-inducing kinase activity, cellular response to mechanical stimulus, defense response to bacterium, defense response to virus, detection of virus, hyperosmotic response, inflammatory response, innate immune response, negative regulation of osteoclast differentiation, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of JNK cascade, positive regulation of NF-kappaB import into nucleus, positive regulation of NF-kappaB transcription factor activity, positive regulation of chemokine biosynthetic process, positive regulation of chemokine production, positive regulation of inflammatory response, positive regulation of interferon-alpha biosynthetic process, positive regulation of interferon-beta biosynthetic process, positive regulation of interferon-beta production, positive regulation of interferon-gamma biosynthetic process, positive regulation of interleukin-12 production, positive regulation of interleukin-6 production, positive regulation of interleukin-8 production, positive regulation of toll-like receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, positive regulation of tumor necrosis factor production, positive regulation of type III interferon production, response to exogenous dsRNA, signal transduction, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor signaling pathway Golgi membrane, cell surface, cytoplasm, endolysosome membrane, endoplasmic reticulum membrane, endosome membrane, integral to membrane, integral to plasma membrane, membrane double-stranded RNA binding, receptor activity, transmembrane signaling receptor activity Human UniProtKB:Q99MB1 TLR4 BHF-UCL UniProtKB {GO:0032755=PMID:19740627, GO:0005515=PMID:19509286, GO:0032715=GO_REF:0000024, GO:0046330=GO_REF:0000019, GO:0007249=Reactome:REACT_25351, GO:0032757=PMID:19740627, GO:0045348=GO_REF:0000019, GO:0002756=Reactome:REACT_6809, GO:0002755=Reactome:REACT_6788, GO:0010572=PMID:16514062, GO:0032496=PMID:16514062, GO:0032497=PMID:19252480, GO:0070373=GO_REF:0000024, GO:0070374=GO_REF:0000019, GO:0032609=GO_REF:0000019, GO:0043123=GO_REF:0000019, GO:0032689=GO_REF:0000024, GO:0031663=PMID:10880523, GO:0042742=PMID:10426995, GO:0032729=GO_REF:0000024, GO:0046696=PMID:19252480, GO:0032728=GO_REF:0000024, GO:0038124=Reactome:REACT_8006, GO:0032760=GO_REF:0000024, GO:0038123=Reactome:REACT_8005, GO:0032727=GO_REF:0000024, GO:0034134=Reactome:REACT_7980, GO:0070434=GO_REF:0000019, GO:0042535=PMID:17951129, GO:0045416=PMID:17951129, GO:0032720=GO_REF:0000024, GO:0032722=PMID:19740627, GO:0070430=GO_REF:0000019, GO:0002224=Reactome:REACT_6966, GO:0045359=GO_REF:0000019, GO:0045084=PMID:15027902, GO:0042116=PMID:10835634, GO:0005887=PMID:15027902, GO:0045087=PMID:15356140, GO:0060729=GO_REF:0000024, GO:0050707=GO_REF:0000002, GO:0035666=Reactome:REACT_25281, GO:0016046=PMID:11254600, GO:0009897=PMID:16514062, GO:0010008=Reactome:REACT_150447, GO:0004888=PMID:11970998, GO:0042346=PMID:19740627, GO:0048471=PMID:15027902, GO:0034142=Reactome:REACT_6894, GO:0032733=GO_REF:0000024, GO:0005886=PMID:19740627, GO:0030890=GO_REF:0000019, GO:0032732=GO_REF:0000024, GO:0001875=PMID:19252480, GO:0032735=GO_REF:0000024, GO:0042088=PMID:11970998, GO:0002537=GO_REF:0000019, GO:0045429=GO_REF:0000019, GO:0000187=GO_REF:0000024, GO:0005737=PMID:19740627, GO:0006955=PMID:10426995, GO:0051092=PMID:12594207, GO:0045944=GO_REF:0000024, GO:0004872=PMID:10426995, GO:0034138=Reactome:REACT_6783, GO:0032707=GO_REF:0000024, GO:0007252=PMID:19740627, GO:0045671=PMID:12133979, GO:0032700=GO_REF:0000024, GO:0001530=PMID:16514062, GO:0050829=PMID:16514062, GO:0071223=GO_REF:0000019, GO:0071222=GO_REF:0000024, GO:0050729=PMID:19740627, GO:0060907=GO_REF:0000019, GO:0051770=GO_REF:0000024, GO:0071260=PMID:19593445} O00206 Toll-like receptor 4 protein 20100311 {GO:0032755=IDA, GO:0005515=IPI, GO:0032715=ISS, GO:0046330=IEA, GO:0007249=TAS, GO:0032757=IDA, GO:0045348=IEA, GO:0002756=TAS, GO:0002755=TAS, GO:0010572=ISS, GO:0032496=IC, GO:0032497=IDA, GO:0070373=ISS, GO:0070374=IEA, GO:0032609=IEA, GO:0043123=IEA, GO:0032689=ISS, GO:0031663=IGI, GO:0042742=TAS, GO:0032729=ISS, GO:0046696=IDA, GO:0032728=ISS, GO:0038124=TAS, GO:0032760=ISS, GO:0038123=TAS, GO:0032727=ISS, GO:0034134=TAS, GO:0070434=IEA, GO:0042535=IDA, GO:0045416=IDA, GO:0032720=ISS, GO:0032722=IDA, GO:0070430=IEA, GO:0002224=TAS, GO:0045359=IEA, GO:0045084=IDA, GO:0042116=IMP, GO:0005887=IDA, GO:0045087=TAS, GO:0060729=ISS, GO:0050707=IEA, GO:0035666=TAS, GO:0016046=NAS, GO:0009897=IDA, GO:0010008=TAS, GO:0004888=NAS, GO:0042346=IDA, GO:0048471=IDA, GO:0034142=TAS, GO:0032733=ISS, GO:0005886=IDA, GO:0030890=IEA, GO:0032732=ISS, GO:0001875=IDA, GO:0032735=ISS, GO:0042088=NAS, GO:0002537=IEA, GO:0045429=IEA, GO:0000187=ISS, GO:0005737=IDA, GO:0006955=TAS, GO:0051092=IDA, GO:0045944=ISS, GO:0004872=TAS, GO:0034138=TAS, GO:0032707=ISS, GO:0007252=IDA, GO:0045671=NAS, GO:0032700=ISS, GO:0001530=IMP, GO:0050829=IC, GO:0071223=IEA, GO:0071222=ISS, GO:0050729=IC, GO:0060907=IEA, GO:0051770=ISS, GO:0071260=IEP} I-kappaB kinase/NF-kappaB cascade, I-kappaB phosphorylation, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, T-helper 1 type immune response, TRIF-dependent toll-like receptor signaling pathway, activation of MAPK activity, cellular response to lipopolysaccharide, cellular response to lipoteichoic acid, cellular response to mechanical stimulus, defense response to Gram-negative bacterium, defense response to bacterium, detection of fungus, detection of lipopolysaccharide, immune response, innate immune response, interferon-gamma production, intestinal epithelial structure maintenance, lipopolysaccharide-mediated signaling pathway, macrophage activation, negative regulation of ERK1 and ERK2 cascade, negative regulation of interferon-gamma production, negative regulation of interleukin-17 production, negative regulation of interleukin-23 production, negative regulation of interleukin-6 production, negative regulation of osteoclast differentiation, negative regulation of tumor necrosis factor production, nitric oxide production involved in inflammatory response, positive regulation of B cell proliferation, positive regulation of ERK1 and ERK2 cascade, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of JNK cascade, positive regulation of MHC class II biosynthetic process, positive regulation of NF-kappaB import into nucleus, positive regulation of NF-kappaB transcription factor activity, positive regulation of chemokine production, positive regulation of inflammatory response, positive regulation of interferon-alpha production, positive regulation of interferon-beta biosynthetic process, positive regulation of interferon-beta production, positive regulation of interferon-gamma production, positive regulation of interleukin-1 production, positive regulation of interleukin-10 production, positive regulation of interleukin-12 biosynthetic process, positive regulation of interleukin-12 production, positive regulation of interleukin-6 production, positive regulation of interleukin-8 biosynthetic process, positive regulation of interleukin-8 production, positive regulation of macrophage cytokine production, positive regulation of nitric oxide biosynthetic process, positive regulation of nitric-oxide synthase biosynthetic process, positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway, positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway, positive regulation of platelet activation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of tumor necrosis factor biosynthetic process, positive regulation of tumor necrosis factor production, regulation of cytokine secretion, response to lipopolysaccharide, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway cytoplasm, endosome membrane, external side of plasma membrane, integral to plasma membrane, lipopolysaccharide receptor complex, perinuclear region of cytoplasm, plasma membrane lipopolysaccharide binding, lipopolysaccharide receptor activity, protein binding, receptor activity, transmembrane signaling receptor activity Human UniProtKB:Q9QUK6 TLR5 BHF-UCL UniProtKB {GO:0005149=PMID:12925853, GO:0034123=PMID:17128265, GO:0005886=Reactome:REACT_27293, GO:0002224=Reactome:REACT_6966, GO:0032757=PMID:17128265, GO:0006954=GO_REF:0000037, GO:0002755=Reactome:REACT_27215, GO:0045087=Reactome:REACT_6802, GO:0050707=GO_REF:0000002, GO:0034166=Reactome:REACT_9027, GO:0016021=GO_REF:0000037, GO:0071260=PMID:19593445, GO:0034146=Reactome:REACT_9061, GO:0042742=GO_REF:0000002, GO:0004888=GO_REF:0000002} O60602 Toll-like receptor 5 protein 20091030 {GO:0005149=IPI, GO:0034123=IDA, GO:0005886=TAS, GO:0002224=TAS, GO:0032757=IDA, GO:0006954=IEA, GO:0002755=TAS, GO:0045087=TAS, GO:0050707=IEA, GO:0034166=TAS, GO:0016021=IEA, GO:0071260=IEP, GO:0034146=TAS, GO:0042742=IEA, GO:0004888=IEA} MyD88-dependent toll-like receptor signaling pathway, cellular response to mechanical stimulus, defense response to bacterium, inflammatory response, innate immune response, positive regulation of interleukin-8 production, positive regulation of toll-like receptor signaling pathway, regulation of cytokine secretion, toll-like receptor 10 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor signaling pathway integral to membrane, plasma membrane interleukin-1 receptor binding, transmembrane signaling receptor activity Human TLR6 Reactome UniProtKB {GO:0034142=Reactome:REACT_6894, GO:0005886=Reactome:REACT_150418, GO:0042088=PMID:11686851, GO:0006955=PMID:10426995, GO:0006954=GO_REF:0000037, GO:0042498=GO_REF:0000019, GO:0002755=Reactome:REACT_6788, GO:0042496=PMID:19931471, GO:0030670=GO_REF:0000039, GO:0004872=PMID:10426995, GO:0043507=PMID:10231569, GO:0043123=PMID:10231569, GO:0042742=PMID:10426995, GO:0071723=PMID:11431423, GO:0045410=PMID:12077222, GO:0038124=Reactome:REACT_8006, GO:0071726=PMID:19931471, GO:0038123=Reactome:REACT_8005, GO:0046982=GO_REF:0000019, GO:0034150=GO_REF:0000002, GO:0007250=PMID:10231569, GO:0034134=Reactome:REACT_7980, GO:0002224=Reactome:REACT_6966, GO:0007165=PMID:10231569, GO:0005887=PMID:10231569, GO:0045087=Reactome:REACT_6802, GO:0035355=GO_REF:0000019, GO:0050707=GO_REF:0000002, GO:0016021=GO_REF:0000002, GO:0004888=GO_REF:0000002} Q9Y2C9 Toll-like receptor 6 protein 20080327 {GO:0034142=TAS, GO:0005886=TAS, GO:0042088=IC, GO:0006955=TAS, GO:0006954=IEA, GO:0042498=IEA, GO:0002755=TAS, GO:0042496=IDA, GO:0030670=IEA, GO:0004872=TAS, GO:0043507=IDA, GO:0043123=IDA, GO:0042742=TAS, GO:0071723=ISS, GO:0045410=ISS, GO:0038124=TAS, GO:0071726=IDA, GO:0038123=TAS, GO:0046982=IEA, GO:0034150=IEA, GO:0007250=NAS, GO:0034134=TAS, GO:0002224=TAS, GO:0007165=TAS, GO:0005887=TAS, GO:0045087=TAS, GO:0035355=IEA, GO:0050707=IEA, GO:0016021=IEA, GO:0004888=IEA} MyD88-dependent toll-like receptor signaling pathway, T-helper 1 type immune response, activation of NF-kappaB-inducing kinase activity, cellular response to diacyl bacterial lipopeptide, defense response to bacterium, detection of diacyl bacterial lipopeptide, immune response, inflammatory response, innate immune response, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of JUN kinase activity, positive regulation of interleukin-6 biosynthetic process, regulation of cytokine secretion, signal transduction, toll-like receptor 2 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 6 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway Toll-like receptor 2-Toll-like receptor 6 protein complex, integral to membrane, integral to plasma membrane, phagocytic vesicle membrane, plasma membrane diacyl lipopeptide binding, lipopeptide binding, protein heterodimerization activity, receptor activity, transmembrane signaling receptor activity Human TLR7 BHF-UCL UniProtKB {GO:0032755=GO_REF:0000019, GO:0003725=PMID:16111635, GO:0042346=PMID:19740627, GO:0003727=GO_REF:0000024, GO:0005886=PMID:19740627, GO:0005783=GO_REF:0000024, GO:0032009=GO_REF:0000024, GO:0042221=GO_REF:0000019, GO:0005764=GO_REF:0000024, GO:0032757=PMID:19740627, GO:0005737=PMID:19740627, GO:0051607=PMID:16188996, GO:0006954=GO_REF:0000037, GO:0036020=Reactome:REACT_118824, GO:0008144=GO_REF:0000019, GO:0002755=GO_REF:0000002, GO:0045078=PMID:16286015, GO:0002282=GO_REF:0000019, GO:0034154=GO_REF:0000019, GO:0007252=PMID:19740627, GO:0045416=PMID:16188996, GO:0032722=PMID:19740627, GO:0002224=Reactome:REACT_9020, GO:0045359=PMID:16286015, GO:0035197=GO_REF:0000024, GO:0000139=Reactome:REACT_118791, GO:0045087=Reactome:REACT_6802, GO:0052033=GO_REF:0000019, GO:0050729=PMID:19740627, GO:0045356=PMID:16286015, GO:0005789=Reactome:REACT_118802, GO:0016021=GO_REF:0000037, GO:0071260=PMID:19593445, GO:0034162=Reactome:REACT_9047, GO:0010008=Reactome:REACT_25392, GO:0004888=GO_REF:0000002, GO:0005768=GO_REF:0000024} Q9NYK1 Toll-like receptor 7 protein 20091112 {GO:0032755=IEA, GO:0003725=IDA, GO:0042346=IDA, GO:0003727=ISS, GO:0005886=IDA, GO:0005783=ISS, GO:0032009=ISS, GO:0042221=IEA, GO:0005764=ISS, GO:0032757=IDA, GO:0005737=IDA, GO:0051607=IMP, GO:0006954=IEA, GO:0036020=TAS, GO:0008144=IEA, GO:0002755=IEA, GO:0045078=IDA, GO:0002282=IEA, GO:0034154=IEA, GO:0007252=IDA, GO:0045416=IMP, GO:0032722=IDA, GO:0002224=TAS, GO:0045359=IDA, GO:0035197=ISS, GO:0000139=TAS, GO:0045087=TAS, GO:0052033=IEA, GO:0050729=IC, GO:0045356=IDA, GO:0005789=TAS, GO:0016021=IEA, GO:0071260=IEP, GO:0034162=TAS, GO:0010008=TAS, GO:0004888=IEA, GO:0005768=ISS} I-kappaB phosphorylation, MyD88-dependent toll-like receptor signaling pathway, cellular response to mechanical stimulus, defense response to virus, inflammatory response, innate immune response, microglial cell activation involved in immune response, pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response, positive regulation of NF-kappaB import into nucleus, positive regulation of chemokine production, positive regulation of inflammatory response, positive regulation of interferon-alpha biosynthetic process, positive regulation of interferon-beta biosynthetic process, positive regulation of interferon-gamma biosynthetic process, positive regulation of interleukin-6 production, positive regulation of interleukin-8 biosynthetic process, positive regulation of interleukin-8 production, response to chemical stimulus, toll-like receptor 7 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor signaling pathway Golgi membrane, cytoplasm, early phagosome, endolysosome membrane, endoplasmic reticulum, endoplasmic reticulum membrane, endosome, endosome membrane, integral to membrane, lysosome, plasma membrane double-stranded RNA binding, drug binding, siRNA binding, single-stranded RNA binding, transmembrane signaling receptor activity Human GO:0042346 TLR8 Reactome UniProtKB {GO:0003725=PMID:16111635, GO:0003727=PMID:14976262, GO:0016064=PMID:16123302, GO:0003723=PMID:16123302, GO:0007249=PMID:12032557, GO:0051607=PMID:16188996, GO:0006954=GO_REF:0000037, GO:0036020=Reactome:REACT_118774, GO:0045078=PMID:16286015, GO:0002755=GO_REF:0000002, GO:0004872=PMID:12032557, GO:0034158=GO_REF:0000002, GO:0045416=PMID:16188996, GO:0009615=PMID:12032557, GO:0002224=Reactome:REACT_9020, GO:0003677=PMID:16123302, GO:0045359=PMID:16286015, GO:0045089=PMID:16123302, GO:0000139=Reactome:REACT_118791, GO:0045087=Reactome:REACT_6802, GO:0045356=PMID:16286015, GO:0005789=Reactome:REACT_118802, GO:0050707=GO_REF:0000002, GO:0016021=PMID:12032557, GO:0071260=PMID:19593445, GO:0034162=Reactome:REACT_9047, GO:0010008=Reactome:REACT_25392} Q9NR97 Toll-like receptor 8 protein 20111019 {GO:0003725=IDA, GO:0003727=IDA, GO:0016064=TAS, GO:0003723=TAS, GO:0007249=IDA, GO:0051607=IMP, GO:0006954=IEA, GO:0036020=TAS, GO:0045078=IDA, GO:0002755=IEA, GO:0004872=NAS, GO:0034158=IEA, GO:0045416=IMP, GO:0009615=IDA, GO:0002224=TAS, GO:0003677=IDA, GO:0045359=IDA, GO:0045089=IDA, GO:0000139=TAS, GO:0045087=TAS, GO:0045356=IDA, GO:0005789=TAS, GO:0050707=IEA, GO:0016021=IC, GO:0071260=IEP, GO:0034162=TAS, GO:0010008=TAS} I-kappaB kinase/NF-kappaB cascade, MyD88-dependent toll-like receptor signaling pathway, cellular response to mechanical stimulus, defense response to virus, immunoglobulin mediated immune response, inflammatory response, innate immune response, positive regulation of innate immune response, positive regulation of interferon-alpha biosynthetic process, positive regulation of interferon-beta biosynthetic process, positive regulation of interferon-gamma biosynthetic process, positive regulation of interleukin-8 biosynthetic process, regulation of cytokine secretion, response to virus, toll-like receptor 8 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor signaling pathway Golgi membrane, endolysosome membrane, endoplasmic reticulum membrane, endosome membrane, integral to membrane DNA binding, RNA binding, double-stranded RNA binding, receptor activity, single-stranded RNA binding Human TLR9 BHF-UCL UniProtKB {GO:0032755=PMID:19740627, GO:0032717=PMID:17128265, GO:0034123=PMID:17128265, GO:0034122=PMID:17128265, GO:0032715=GO_REF:0000024, GO:0046330=PMID:17128265, GO:0005764=GO_REF:0000024, GO:0032757=PMID:17128265, GO:0002755=GO_REF:0000002, GO:0045078=PMID:16286015, GO:0043123=PMID:17128265, GO:0042742=PMID:11130078, GO:0032728=GO_REF:0000024, GO:0032760=GO_REF:0000024, GO:0032722=PMID:19740627, GO:0002224=Reactome:REACT_9020, GO:0045359=PMID:16286015, GO:0045087=PMID:15356140, GO:0045356=PMID:16286015, GO:0005789=Reactome:REACT_118802, GO:0050707=GO_REF:0000002, GO:0010008=Reactome:REACT_118633, GO:0034162=Reactome:REACT_9047, GO:0004888=GO_REF:0000002, GO:0008286=Reactome:REACT_498, GO:0042346=PMID:19740627, GO:0005886=PMID:19740627, GO:0032733=GO_REF:0000024, GO:0005783=GO_REF:0000024, GO:0002237=PMID:15356140, GO:0032735=GO_REF:0000024, GO:0032009=GO_REF:0000024, GO:0016323=PMID:17128265, GO:0005737=PMID:19740627, GO:0016324=PMID:17128265, GO:0006954=GO_REF:0000037, GO:0051092=PMID:17128265, GO:0030277=GO_REF:0000024, GO:0036020=Reactome:REACT_118824, GO:0045944=GO_REF:0000024, GO:0043507=PMID:17128265, GO:0005149=PMID:12925853, GO:0032741=GO_REF:0000024, GO:0007252=PMID:19740627, GO:0005576=PMID:11130078, GO:0032088=PMID:17128265, GO:0000139=Reactome:REACT_118791, GO:0035197=PMID:15723075, GO:0050729=PMID:19740627, GO:0016021=GO_REF:0000037, GO:0051770=GO_REF:0000024, GO:0005768=GO_REF:0000024} Q9NR96 Toll-like receptor 9 protein 20100304 {GO:0032755=IDA, GO:0032717=IDA, GO:0034123=IDA, GO:0034122=IDA, GO:0032715=ISS, GO:0046330=IC, GO:0005764=ISS, GO:0032757=IDA, GO:0002755=IEA, GO:0045078=IDA, GO:0043123=IDA, GO:0042742=NAS, GO:0032728=ISS, GO:0032760=ISS, GO:0032722=IDA, GO:0002224=TAS, GO:0045359=IDA, GO:0045087=TAS, GO:0045356=IDA, GO:0005789=TAS, GO:0050707=IEA, GO:0010008=TAS, GO:0034162=TAS, GO:0004888=IEA, GO:0008286=TAS, GO:0042346=IDA, GO:0005886=IDA, GO:0032733=ISS, GO:0005783=ISS, GO:0002237=TAS, GO:0032735=ISS, GO:0032009=ISS, GO:0016323=IDA, GO:0005737=IDA, GO:0016324=IDA, GO:0006954=IEA, GO:0051092=IDA, GO:0030277=ISS, GO:0036020=TAS, GO:0045944=ISS, GO:0043507=IDA, GO:0005149=IPI, GO:0032741=ISS, GO:0007252=IDA, GO:0005576=NAS, GO:0032088=IDA, GO:0000139=TAS, GO:0035197=IMP, GO:0050729=IC, GO:0016021=IEA, GO:0051770=ISS, GO:0005768=ISS} I-kappaB phosphorylation, MyD88-dependent toll-like receptor signaling pathway, defense response to bacterium, inflammatory response, innate immune response, insulin receptor signaling pathway, maintenance of gastrointestinal epithelium, negative regulation of NF-kappaB transcription factor activity, negative regulation of interleukin-6 production, negative regulation of interleukin-8 production, negative regulation of toll-like receptor signaling pathway, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of JNK cascade, positive regulation of JUN kinase activity, positive regulation of NF-kappaB import into nucleus, positive regulation of NF-kappaB transcription factor activity, positive regulation of chemokine production, positive regulation of inflammatory response, positive regulation of interferon-alpha biosynthetic process, positive regulation of interferon-beta biosynthetic process, positive regulation of interferon-beta production, positive regulation of interferon-gamma biosynthetic process, positive regulation of interleukin-10 production, positive regulation of interleukin-12 production, positive regulation of interleukin-18 production, positive regulation of interleukin-6 production, positive regulation of interleukin-8 production, positive regulation of nitric-oxide synthase biosynthetic process, positive regulation of toll-like receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, positive regulation of tumor necrosis factor production, regulation of cytokine secretion, response to molecule of bacterial origin, toll-like receptor 9 signaling pathway, toll-like receptor signaling pathway Golgi membrane, apical plasma membrane, basolateral plasma membrane, cytoplasm, early phagosome, endolysosome membrane, endoplasmic reticulum, endoplasmic reticulum membrane, endosome, endosome membrane, extracellular region, integral to membrane, lysosome, plasma membrane interleukin-1 receptor binding, siRNA binding, transmembrane signaling receptor activity Human UniProtKB:Q9EQU3 TLX1 IntAct UniProtKB {GO:0005515=PMID:22516263, GO:0048645=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0008284=GO_REF:0000019, GO:0045165=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0046982=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0030182=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0048536=GO_REF:0000019, GO:0007417=GO_REF:0000019} P31314 T-cell leukemia homeobox protein 1 protein 20130415 {GO:0005515=IPI, GO:0048645=IEA, GO:0043565=IEA, GO:0008284=IEA, GO:0045165=IEA, GO:0003700=IEA, GO:0046982=IEA, GO:0045944=IEA, GO:0030182=IEA, GO:0005634=IEA, GO:0048536=IEA, GO:0007417=IEA} cell fate commitment, central nervous system development, neuron differentiation, organ formation, positive regulation of cell proliferation, positive regulation of transcription from RNA polymerase II promoter, spleen development nucleus protein binding, protein heterodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:P27577 TLX2 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000019, GO:0001707=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0050774=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0006351=GO_REF:0000037, GO:0048484=GO_REF:0000019} O43763 T-cell leukemia homeobox protein 2 protein 20061026 {GO:0043565=IEA, GO:0003674=ND, GO:0008150=ND, GO:0005737=IEA, GO:0001707=IEA, GO:0003700=IEA, GO:0050774=IEA, GO:0005634=IEA, GO:0005575=ND, GO:0006351=IEA, GO:0048484=IEA} biological_process, enteric nervous system development, mesoderm formation, negative regulation of dendrite morphogenesis, transcription, DNA-dependent cellular_component, cytoplasm, nucleus molecular_function, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human TLX3 IntAct UniProtKB {GO:0005515=PMID:22516263, GO:0043565=GO_REF:0000002, GO:0002087=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0045665=GO_REF:0000019, GO:0007585=GO_REF:0000019, GO:0048665=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0007417=GO_REF:0000019, GO:0001764=GO_REF:0000019} O43711 T-cell leukemia homeobox protein 3 protein 20130415 {GO:0005515=IPI, GO:0043565=IEA, GO:0002087=IEA, GO:0003700=IEA, GO:0045665=IEA, GO:0007585=IEA, GO:0048665=IEA, GO:0005634=IEA, GO:0007417=IEA, GO:0001764=IEA} central nervous system development, negative regulation of neuron differentiation, neuron fate specification, neuron migration, regulation of respiratory gaseous exchange by neurological system process, respiratory gaseous exchange nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:P27577 TM2D1 UniProtKB UniProtKB {GO:0001540=GO_REF:0000019, GO:0005887=GO_REF:0000019, GO:0004930=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q9BX74 TM2 domain-containing protein 1 protein 20130413 {GO:0001540=IEA, GO:0005887=IEA, GO:0004930=IEA, GO:0006915=IEA, GO:0016021=IEA} apoptotic process integral to membrane, integral to plasma membrane G-protein coupled receptor activity, beta-amyloid binding Human UniProtKB-KW:KW-0812 TM2D3 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9BRN9 TM2 domain-containing protein 3 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TM4SF1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005887=PMID:7510285, GO:0016021=GO_REF:0000002} P30408 Transmembrane 4 L6 family member 1 protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0005887=IDA, GO:0016021=IEA} biological_process integral to membrane, integral to plasma membrane molecular_function Human TM4SF20 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q53R12 Transmembrane 4 L6 family member 20 protein 20130413 {GO:0005886=IEA, GO:0016021=IEA} integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 TM4SF4 ENSEMBL UniProtKB {GO:0016021=GO_REF:0000037, GO:0042246=GO_REF:0000019} P48230 Transmembrane 4 L6 family member 4 protein 20130413 {GO:0016021=IEA, GO:0042246=IEA} tissue regeneration integral to membrane Human Ensembl:ENSRNOP00000022105 TM7SF2 Reactome UniProtKB {GO:0006695=Reactome:REACT_9405, GO:0050613=GO_REF:0000003, GO:0016020=GO_REF:0000002, GO:0005887=PMID:9878250, GO:0005783=PMID:9878250, GO:0005789=Reactome:REACT_147728, GO:0044281=Reactome:REACT_111217, GO:0016628=GO_REF:0000002} O76062 Delta(14)-sterol reductase protein 20130301 {GO:0006695=TAS, GO:0050613=IEA, GO:0016020=IEA, GO:0005887=TAS, GO:0005783=TAS, GO:0005789=TAS, GO:0044281=TAS, GO:0016628=IEA} cholesterol biosynthetic process, small molecule metabolic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to plasma membrane, membrane delta14-sterol reductase activity, oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor Human TM7SF3 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q9NS93 Transmembrane 7 superfamily member 3 protein 20130413 {GO:0005886=IEA, GO:0016021=IEA} integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 TM9SF1 UniProtKB UniProtKB {GO:0000421=GO_REF:0000039, GO:0006914=GO_REF:0000037, GO:0031410=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005765=GO_REF:0000039, GO:0015031=GO_REF:0000002} O15321 Transmembrane 9 superfamily member 1 protein 20130413 {GO:0000421=IEA, GO:0006914=IEA, GO:0031410=IEA, GO:0016021=IEA, GO:0005765=IEA, GO:0015031=IEA} autophagy, protein transport autophagic vacuole membrane, cytoplasmic vesicle, integral to membrane, lysosomal membrane Human UniProtKB-SubCell:SL-0157 TM9SF2 PINC UniProtKB {GO:0005887=PMID:9729438, GO:0006810=PMID:9729438, GO:0010008=GO_REF:0000039, GO:0005768=PMID:9729438} Q99805 Transmembrane 9 superfamily member 2 protein 20030904 {GO:0005887=TAS, GO:0006810=TAS, GO:0010008=IEA, GO:0005768=TAS} transport endosome, endosome membrane, integral to plasma membrane Human TM9SF3 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9HD45 Transmembrane 9 superfamily member 3 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TM9SF4 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q92544 Transmembrane 9 superfamily member 4 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMBIM1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0005765=PMID:16607040, GO:0010008=PMID:16607040} Q969X1 Protein lifeguard 3 protein 20120116 {GO:0016021=IEA, GO:0005765=IDA, GO:0010008=IDA} endosome membrane, integral to membrane, lysosomal membrane Human TMBIM4 UniProtKB UniProtKB {GO:0005515=PMID:19553469, GO:0050848=PMID:19553469, GO:0043066=PMID:17319741, GO:0005795=PMID:17319741, GO:0000139=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q9HC24 Protein lifeguard 4 protein 20120117 {GO:0005515=IPI, GO:0050848=IDA, GO:0043066=IMP, GO:0005795=IDA, GO:0000139=IEA, GO:0006915=IEA, GO:0016021=IEA} apoptotic process, negative regulation of apoptotic process, regulation of calcium-mediated signaling Golgi membrane, Golgi stack, integral to membrane protein binding Human TMBIM6 PINC UniProtKB {GO:0006986=GO_REF:0000037, GO:0043066=GO_REF:0000002, GO:0005887=PMID:10087504, GO:0005783=PMID:10087504, GO:0005789=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0005634=PMID:8530040, GO:0016021=GO_REF:0000038} P55061 Bax inhibitor 1 protein 20030904 {GO:0006986=IEA, GO:0043066=IEA, GO:0005887=TAS, GO:0005783=TAS, GO:0005789=IEA, GO:0006915=IEA, GO:0005634=TAS, GO:0016021=IEA} apoptotic process, negative regulation of apoptotic process, response to unfolded protein endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, integral to plasma membrane, nucleus Human TMC1 ENSEMBL UniProtKB {GO:0050910=GO_REF:0000019, GO:0060005=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0009897=GO_REF:0000019, GO:0060117=GO_REF:0000019, GO:0032426=GO_REF:0000019, GO:0006811=GO_REF:0000037} Q8TDI8 Transmembrane channel-like protein 1 protein 20130413 {GO:0050910=IEA, GO:0060005=IEA, GO:0016021=IEA, GO:0009897=IEA, GO:0060117=IEA, GO:0032426=IEA, GO:0006811=IEA} auditory receptor cell development, detection of mechanical stimulus involved in sensory perception of sound, ion transport, vestibular reflex external side of plasma membrane, integral to membrane, stereocilium bundle tip Human Ensembl:ENSMUSP00000040859 TMC5 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0006811=GO_REF:0000037} Q6UXY8 Transmembrane channel-like protein 5 protein 20130413 {GO:0016021=IEA, GO:0006811=IEA} ion transport integral to membrane Human UniProtKB-KW:KW-0812 TMC6 UniProtKB UniProtKB {GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0006811=GO_REF:0000037} Q7Z403 Transmembrane channel-like protein 6 protein 20130413 {GO:0005789=IEA, GO:0016021=IEA, GO:0006811=IEA} ion transport endoplasmic reticulum membrane, integral to membrane Human UniProtKB-SubCell:SL-0097 TMC7 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0006811=GO_REF:0000037} Q7Z402 Transmembrane channel-like protein 7 protein 20130413 {GO:0016021=IEA, GO:0006811=IEA} ion transport integral to membrane Human UniProtKB-KW:KW-0812 TMCC1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} O94876 Transmembrane and coiled-coil domains protein 1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMCC2 IntAct UniProtKB {GO:0005515=PMID:21593558, GO:0016021=GO_REF:0000037} O75069 Transmembrane and coiled-coil domains protein 2 protein 20130415 {GO:0005515=IPI, GO:0016021=IEA} integral to membrane protein binding Human UniProtKB:P02649 TMCC3 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9ULS5 Transmembrane and coiled-coil domains protein 3 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMCO1 UniProtKB UniProtKB {GO:0000139=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q9UM00 Transmembrane and coiled-coil domain-containing protein 1 protein 20130413 {GO:0000139=IEA, GO:0016020=IEA, GO:0005789=IEA, GO:0016021=IEA} Golgi membrane, endoplasmic reticulum membrane, integral to membrane, membrane Human UniProtKB-SubCell:SL-0097 TMCO3 UniProtKB UniProtKB {GO:0015299=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q6UWJ1 Transmembrane and coiled-coil domain-containing protein 3 protein 20130413 {GO:0015299=IEA, GO:0016021=IEA} integral to membrane solute:hydrogen antiporter activity Human UniProtKB-KW:KW-0812 TMCO6 UniProtKB UniProtKB {GO:0005737=GO_REF:0000002, GO:0008565=GO_REF:0000002, GO:0005634=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0006606=GO_REF:0000002} Q96DC7 Transmembrane and coiled-coil domain-containing protein 6 protein 20130413 {GO:0005737=IEA, GO:0008565=IEA, GO:0005634=IEA, GO:0016021=IEA, GO:0006606=IEA} protein import into nucleus cytoplasm, integral to membrane, nucleus protein transporter activity Human UniProtKB-KW:KW-0812 TMED1 HGNC UniProtKB {GO:0005515=PMID:8621446, GO:0005793=PMID:12237308, GO:0005794=PMID:12237308, GO:0005886=GO_REF:0000039, GO:0005783=PMID:12237308, GO:0005102=PMID:8621446, GO:0007267=PMID:8621446, GO:0015031=GO_REF:0000037, GO:0007165=PMID:8621446, GO:0033116=GO_REF:0000039, GO:0006810=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q13445 Transmembrane emp24 domain-containing protein 1 protein 20041124 {GO:0005515=IPI, GO:0005793=IDA, GO:0005794=IDA, GO:0005886=IEA, GO:0005783=IDA, GO:0005102=TAS, GO:0007267=TAS, GO:0015031=IEA, GO:0007165=TAS, GO:0033116=IEA, GO:0006810=IEA, GO:0005789=IEA, GO:0016021=IEA} cell-cell signaling, protein transport, signal transduction, transport Golgi apparatus, endoplasmic reticulum, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment, endoplasmic reticulum-Golgi intermediate compartment membrane, integral to membrane, plasma membrane protein binding, receptor binding Human UniProtKB:Q01638 TMED10 IntAct UniProtKB {GO:0005515=PMID:16641999, GO:0005801=GO_REF:0000024, GO:0035459=PMID:20427317, GO:0030137=GO_REF:0000024, GO:0005886=GO_REF:0000024, GO:0005783=PMID:12237308, GO:0048208=PMID:20427317, GO:0006886=PMID:20427317, GO:0051259=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0048205=PMID:10761932, GO:0035964=PMID:10052452, GO:0045055=GO_REF:0000024, GO:0033116=GO_REF:0000039, GO:0006810=GO_REF:0000002, GO:0007030=GO_REF:0000019, GO:0001101=GO_REF:0000019, GO:0030140=GO_REF:0000024, GO:0030658=GO_REF:0000039, GO:0042470=GO_REF:0000039, GO:0005793=PMID:12237308, GO:0005794=PMID:12237308, GO:0070765=PMID:16641999, GO:0001822=GO_REF:0000019, GO:0006890=GO_REF:0000024, GO:0043279=GO_REF:0000019, GO:0034205=PMID:16641999, GO:0006888=PMID:20427317, GO:0042589=GO_REF:0000024, GO:0048199=GO_REF:0000024, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000024, GO:0030667=GO_REF:0000024} P49755 Transmembrane emp24 domain-containing protein 10 protein 20130415 {GO:0005515=IPI, GO:0005801=ISS, GO:0035459=TAS, GO:0030137=ISS, GO:0005886=ISS, GO:0005783=IDA, GO:0048208=TAS, GO:0006886=IDA, GO:0051259=IEA, GO:0032403=IEA, GO:0048205=TAS, GO:0035964=IDA, GO:0045055=ISS, GO:0033116=IEA, GO:0006810=IEA, GO:0007030=IEA, GO:0001101=IEA, GO:0030140=ISS, GO:0030658=IEA, GO:0042470=IEA, GO:0005793=IDA, GO:0005794=IDA, GO:0070765=IDA, GO:0001822=IEA, GO:0006890=ISS, GO:0043279=IEA, GO:0034205=IMP, GO:0006888=TAS, GO:0042589=ISS, GO:0048199=ISS, GO:0005789=IEA, GO:0016021=ISS, GO:0030667=ISS} COPI coating of Golgi vesicle, COPI-coated vesicle budding, COPII vesicle coating, ER to Golgi vesicle-mediated transport, Golgi organization, beta-amyloid formation, cargo loading into vesicle, intracellular protein transport, kidney development, protein oligomerization, regulated secretory pathway, response to acid, response to alkaloid, retrograde vesicle-mediated transport, Golgi to ER, transport, vesicle targeting, to, from or within Golgi COPI-coated vesicle, Golgi apparatus, cis-Golgi network, endoplasmic reticulum, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment, endoplasmic reticulum-Golgi intermediate compartment membrane, gamma-secretase complex, integral to membrane, melanosome, plasma membrane, secretory granule membrane, trans-Golgi network transport vesicle, transport vesicle membrane, zymogen granule membrane protein binding, protein complex binding Human UniProtKB:Q9NZ42 TMED2 HPA UniProtKB {GO:0005515=PMID:20427317, GO:0035459=PMID:20427317, GO:0030137=GO_REF:0000024, GO:0005783=PMID:12237308, GO:0072661=PMID:20361938, GO:0048208=PMID:20427317, GO:0006886=PMID:20427317, GO:0048205=PMID:10761932, GO:0043231=GO_REF:0000052, GO:0001947=GO_REF:0000019, GO:0035264=GO_REF:0000019, GO:0032525=GO_REF:0000019, GO:0032580=GO_REF:0000039, GO:0033116=GO_REF:0000039, GO:0007030=PMID:17693410, GO:0006810=GO_REF:0000002, GO:0034260=PMID:10761932, GO:0005793=PMID:12237308, GO:0005794=PMID:12237308, GO:0001893=GO_REF:0000019, GO:0001892=GO_REF:0000019, GO:0001843=GO_REF:0000019, GO:0036342=GO_REF:0000019, GO:0006888=PMID:20427317, GO:0010628=GO_REF:0000019, GO:0042589=GO_REF:0000024, GO:0030663=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000024} Q15363 Transmembrane emp24 domain-containing protein 2 protein 20100326 {GO:0005515=IPI, GO:0035459=TAS, GO:0030137=ISS, GO:0005783=IDA, GO:0072661=IDA, GO:0048208=TAS, GO:0006886=IDA, GO:0048205=TAS, GO:0043231=IDA, GO:0001947=IEA, GO:0035264=IEA, GO:0032525=IEA, GO:0032580=IEA, GO:0033116=IEA, GO:0007030=IMP, GO:0006810=IEA, GO:0034260=IDA, GO:0005793=IDA, GO:0005794=IDA, GO:0001893=IEA, GO:0001892=IEA, GO:0001843=IEA, GO:0036342=IEA, GO:0006888=TAS, GO:0010628=IEA, GO:0042589=ISS, GO:0030663=IEA, GO:0005789=IEA, GO:0016021=ISS} COPI coating of Golgi vesicle, COPII vesicle coating, ER to Golgi vesicle-mediated transport, Golgi organization, cargo loading into vesicle, embryonic placenta development, heart looping, intracellular protein transport, maternal placenta development, multicellular organism growth, negative regulation of GTPase activity, neural tube closure, positive regulation of gene expression, post-anal tail morphogenesis, protein targeting to plasma membrane, somite rostral/caudal axis specification, transport COPI-coated vesicle, COPI-coated vesicle membrane, Golgi apparatus, Golgi cisterna membrane, endoplasmic reticulum, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment, endoplasmic reticulum-Golgi intermediate compartment membrane, integral to membrane, intracellular membrane-bounded organelle, zymogen granule membrane protein binding Human TMED3 UniProtKB UniProtKB {GO:0030126=GO_REF:0000024, GO:0005793=PMID:12237308, GO:0005794=PMID:12237308, GO:0005783=PMID:12237308, GO:0033116=GO_REF:0000039, GO:0032580=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0006810=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0015031=GO_REF:0000037} Q9Y3Q3 Transmembrane emp24 domain-containing protein 3 protein 20110928 {GO:0030126=ISS, GO:0005793=IDA, GO:0005794=IDA, GO:0005783=IDA, GO:0033116=IEA, GO:0032580=IEA, GO:0005789=IEA, GO:0006810=IEA, GO:0016021=IEA, GO:0015031=IEA} protein transport, transport COPI vesicle coat, Golgi apparatus, Golgi cisterna membrane, endoplasmic reticulum, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment, endoplasmic reticulum-Golgi intermediate compartment membrane, integral to membrane Human UniProtKB:Q6AY25 TMED4 GOC UniProtKB {GO:0007165=PMID:12761501, GO:0005789=GO_REF:0000039, GO:0006810=GO_REF:0000002, GO:0004871=PMID:12761501, GO:0016021=GO_REF:0000037, GO:0043123=PMID:12761501, GO:0015031=GO_REF:0000037} Q7Z7H5 Transmembrane emp24 domain-containing protein 4 protein 20130413 {GO:0007165=IMP, GO:0005789=IEA, GO:0006810=IEA, GO:0004871=IMP, GO:0016021=IEA, GO:0043123=IMP, GO:0015031=IEA} positive regulation of I-kappaB kinase/NF-kappaB cascade, protein transport, signal transduction, transport endoplasmic reticulum membrane, integral to membrane signal transducer activity Human TMED5 UniProtKB UniProtKB {GO:0005801=PMID:19948005, GO:0005793=PMID:19948005, GO:0005794=GO_REF:0000039, GO:0033116=GO_REF:0000039, GO:0090161=PMID:19948005, GO:0005789=GO_REF:0000039, GO:0006810=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0070971=PMID:19948005} Q9Y3A6 Transmembrane emp24 domain-containing protein 5 protein 20110930 {GO:0005801=IDA, GO:0005793=IDA, GO:0005794=IEA, GO:0033116=IEA, GO:0090161=IMP, GO:0005789=IEA, GO:0006810=IEA, GO:0016021=IEA, GO:0015031=IEA, GO:0070971=IDA} Golgi ribbon formation, protein transport, transport Golgi apparatus, cis-Golgi network, endoplasmic reticulum exit site, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment, endoplasmic reticulum-Golgi intermediate compartment membrane, integral to membrane Human TMED7 UniProtKB UniProtKB {GO:0030126=PMID:10359607, GO:0005793=PMID:10359607, GO:0030127=PMID:10359607, GO:0005794=PMID:12237308, GO:0005783=PMID:12237308, GO:0033116=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0006810=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0015031=GO_REF:0000037} Q9Y3B3 Transmembrane emp24 domain-containing protein 7 protein 20110930 {GO:0030126=TAS, GO:0005793=IDA, GO:0030127=TAS, GO:0005794=IDA, GO:0005783=IDA, GO:0033116=IEA, GO:0005789=IEA, GO:0006810=IEA, GO:0016021=IEA, GO:0015031=IEA} protein transport, transport COPI vesicle coat, COPII vesicle coat, Golgi apparatus, endoplasmic reticulum, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment, endoplasmic reticulum-Golgi intermediate compartment membrane, integral to membrane Human TMED8 InterPro UniProtKB {GO:0006810=GO_REF:0000002, GO:0016021=GO_REF:0000002} Q6PL24 Protein TMED8 protein 20130413 {GO:0006810=IEA, GO:0016021=IEA} transport integral to membrane Human InterPro:IPR009038 TMED9 UniProtKB UniProtKB {GO:0010638=PMID:18287528, GO:0005793=PMID:12237308, GO:0005794=PMID:12237308, GO:0005783=PMID:12237308, GO:0034498=PMID:18287528, GO:0033116=GO_REF:0000039, GO:0007030=PMID:18287528, GO:0005789=GO_REF:0000039, GO:0032527=PMID:18287528, GO:0016021=GO_REF:0000037, GO:0030140=PMID:9527489, GO:0048205=PMID:18287528} Q9BVK6 Transmembrane emp24 domain-containing protein 9 protein 20110930 {GO:0010638=IMP, GO:0005793=IDA, GO:0005794=IDA, GO:0005783=IDA, GO:0034498=IMP, GO:0033116=IEA, GO:0007030=IMP, GO:0005789=IEA, GO:0032527=IMP, GO:0016021=IEA, GO:0030140=TAS, GO:0048205=IMP} COPI coating of Golgi vesicle, Golgi organization, early endosome to Golgi transport, positive regulation of organelle organization, protein exit from endoplasmic reticulum Golgi apparatus, endoplasmic reticulum, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment, endoplasmic reticulum-Golgi intermediate compartment membrane, integral to membrane, trans-Golgi network transport vesicle Human TMEFF1 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q8IYR6 Tomoregulin-1 protein 20130413 {GO:0005886=IEA, GO:0007275=IEA, GO:0016021=IEA} multicellular organismal development integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 TMEFF2 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0005576=GO_REF:0000039, GO:0016021=PMID:10987305} Q9UIK5 Tomoregulin-2 protein 20011003 {GO:0003674=ND, GO:0005576=IEA, GO:0016021=NAS} extracellular region, integral to membrane molecular_function Human TMEM100 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0048471=GO_REF:0000019, GO:0007219=GO_REF:0000019, GO:0043491=GO_REF:0000019, GO:0060842=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037, GO:0001525=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0001570=GO_REF:0000019} Q9NV29 Transmembrane protein 100 protein 20090107 {GO:0008150=ND, GO:0003674=ND, GO:0048471=IEA, GO:0007219=IEA, GO:0043491=IEA, GO:0060842=IEA, GO:0005575=ND, GO:0016021=IEA, GO:0001525=IEA, GO:0001701=IEA, GO:0001570=IEA} Notch signaling pathway, angiogenesis, arterial endothelial cell differentiation, biological_process, in utero embryonic development, protein kinase B signaling cascade, vasculogenesis cellular_component, integral to membrane, perinuclear region of cytoplasm molecular_function Human TMEM101 GOC UniProtKB {GO:0007165=PMID:12761501, GO:0004871=PMID:12761501, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037, GO:0043123=PMID:12761501} Q96IK0 Transmembrane protein 101 protein 20130413 {GO:0007165=IMP, GO:0004871=IMP, GO:0005575=ND, GO:0016021=IEA, GO:0043123=IMP} positive regulation of I-kappaB kinase/NF-kappaB cascade, signal transduction cellular_component, integral to membrane signal transducer activity Human TMEM102 UniProtKB UniProtKB {GO:0005622=PMID:17828305, GO:0005515=PMID:17828305, GO:0007165=PMID:17828305, GO:0009986=PMID:17828305, GO:0005886=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0042981=PMID:17828305, GO:0016021=GO_REF:0000037, GO:0034097=PMID:17828305} Q8N9M5 Transmembrane protein 102 protein 20090108 {GO:0005622=IDA, GO:0005515=IPI, GO:0007165=IDA, GO:0009986=IDA, GO:0005886=IEA, GO:0006915=IEA, GO:0042981=IDA, GO:0016021=IEA, GO:0034097=IDA} apoptotic process, regulation of apoptotic process, response to cytokine stimulus, signal transduction cell surface, integral to membrane, intracellular, plasma membrane protein binding Human TMEM104 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} Q8NE00 Transmembrane protein 104 protein 20090107 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND, GO:0016021=IEA} biological_process cellular_component, integral to membrane molecular_function Human TMEM106A UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} Q96A25 Transmembrane protein 106A protein 20090107 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND, GO:0016021=IEA} biological_process cellular_component, integral to membrane molecular_function Human TMEM106B UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0031902=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037, GO:0005765=GO_REF:0000039} Q9NUM4 Transmembrane protein 106B protein 20090107 {GO:0008150=ND, GO:0003674=ND, GO:0031902=IEA, GO:0005575=ND, GO:0016021=IEA, GO:0005765=IEA} biological_process cellular_component, integral to membrane, late endosome membrane, lysosomal membrane molecular_function Human TMEM106C UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005789=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} Q9BVX2 Transmembrane protein 106C protein 20090107 {GO:0008150=ND, GO:0003674=ND, GO:0005789=IEA, GO:0005575=ND, GO:0016021=IEA} biological_process cellular_component, endoplasmic reticulum membrane, integral to membrane molecular_function Human TMEM107 UniProtKB UniProtKB {GO:0042384=GO_REF:0000024, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0021532=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037, GO:0042733=GO_REF:0000019} Q6UX40 Transmembrane protein 107 protein 20120809 {GO:0042384=ISS, GO:0008150=ND, GO:0003674=ND, GO:0021532=IEA, GO:0005575=ND, GO:0016021=IEA, GO:0042733=IEA} biological_process, cilium assembly, embryonic digit morphogenesis, neural tube patterning cellular_component, integral to membrane molecular_function Human UniProtKB:Q9CPV0 TMEM108 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} Q6UXF1 Transmembrane protein 108 protein 20090107 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND, GO:0016021=IEA} biological_process cellular_component, integral to membrane molecular_function Human TMEM109 HPA UniProtKB {GO:0005640=GO_REF:0000039, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0042771=GO_REF:0000019, GO:0031965=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0033017=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0016021=GO_REF:0000037} Q9BVC6 Transmembrane protein 109 protein 20101115 {GO:0005640=IEA, GO:0008150=ND, GO:0003674=ND, GO:0042771=IEA, GO:0031965=IDA, GO:0005737=IDA, GO:0005730=IDA, GO:0033017=IEA, GO:0005634=IDA, GO:0016021=IEA} biological_process, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator cytoplasm, integral to membrane, nuclear membrane, nuclear outer membrane, nucleolus, nucleus, sarcoplasmic reticulum membrane molecular_function Human TMEM11 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0003674=GO_REF:0000015, GO:0005887=PMID:2110658, GO:0031305=PMID:21274005, GO:0007005=PMID:21274005} P17152 Transmembrane protein 11, mitochondrial protein 20130415 {GO:0005515=IPI, GO:0003674=ND, GO:0005887=NAS, GO:0031305=IDA, GO:0007005=IMP} mitochondrion organization integral to mitochondrial inner membrane, integral to plasma membrane molecular_function, protein binding Human UniProtKB:Q12983 TMEM115 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008285=PMID:17973242, GO:0016021=GO_REF:0000037} Q12893 Transmembrane protein 115 protein 20090130 {GO:0003674=ND, GO:0008285=NAS, GO:0016021=IEA} negative regulation of cell proliferation integral to membrane molecular_function Human TMEM120A UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} Q9BXJ8 Transmembrane protein 120A protein 20090107 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND, GO:0016021=IEA} biological_process cellular_component, integral to membrane molecular_function Human TMEM123 UniProtKB UniProtKB {GO:0004872=PMID:9600958, GO:0016021=PMID:11481458, GO:0070267=PMID:9600958, GO:0009897=PMID:9600958} Q8N131 Porimin protein 20090108 {GO:0004872=NAS, GO:0016021=NAS, GO:0070267=IDA, GO:0009897=IDA} oncosis external side of plasma membrane, integral to membrane receptor activity Human TMEM126A BHF-UCL UniProtKB {GO:0005739=GO_REF:0000054, GO:0003674=GO_REF:0000015, GO:0021554=PMID:19327736, GO:0016021=GO_REF:0000037} Q9H061 Transmembrane protein 126A protein 20110711 {GO:0005739=IDA, GO:0003674=ND, GO:0021554=IMP, GO:0016021=IEA} optic nerve development integral to membrane, mitochondrion molecular_function Human TMEM126B UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0031966=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} Q8IUX1 Transmembrane protein 126B protein 20090107 {GO:0008150=ND, GO:0003674=ND, GO:0031966=IEA, GO:0005575=ND, GO:0016021=IEA} biological_process cellular_component, integral to membrane, mitochondrial membrane molecular_function Human TMEM127 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0032007=PMID:20154675, GO:0005737=PMID:20154675, GO:0008285=PMID:20154675, GO:0005886=PMID:20154675, GO:0016021=GO_REF:0000037} O75204 Transmembrane protein 127 protein 20100809 {GO:0003674=ND, GO:0032007=IMP, GO:0005737=IDA, GO:0008285=IMP, GO:0005886=IDA, GO:0016021=IEA} negative regulation of TOR signaling cascade, negative regulation of cell proliferation cytoplasm, integral to membrane, plasma membrane molecular_function Human TMEM128 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} Q5BJH2 Transmembrane protein 128 protein 20090107 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND, GO:0016021=IEA} biological_process cellular_component, integral to membrane molecular_function Human TMEM129 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} A0AVI4 Transmembrane protein 129 protein 20090107 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND, GO:0016021=IEA} biological_process cellular_component, integral to membrane molecular_function Human TMEM131 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} Q92545 Transmembrane protein 131 protein 20090501 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND, GO:0016021=IEA} biological_process cellular_component, integral to membrane molecular_function Human TMEM132A UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0000139=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} Q24JP5 Transmembrane protein 132A protein 20090501 {GO:0003674=ND, GO:0008150=ND, GO:0000139=IEA, GO:0005789=IEA, GO:0005575=ND, GO:0016021=IEA} biological_process Golgi membrane, cellular_component, endoplasmic reticulum membrane, integral to membrane molecular_function Human TMEM132C UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} Q8N3T6 Transmembrane protein 132C protein 20090501 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND, GO:0016021=IEA} biological_process cellular_component, integral to membrane molecular_function Human TMEM132D IntAct UniProtKB {GO:0005515=PMID:19389623, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0010923=PMID:19389623, GO:0016021=PMID:12966072} Q14C87 Transmembrane protein 132D protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0003674=ND, GO:0010923=IDA, GO:0016021=NAS} biological_process, negative regulation of phosphatase activity integral to membrane molecular_function, protein binding Human UniProtKB:P62136 TMEM134 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9H6X4 Transmembrane protein 134 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM135 UniProtKB UniProtKB {GO:0007031=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0005777=GO_REF:0000024} Q86UB9 Transmembrane protein 135 protein 20110704 {GO:0007031=ISS, GO:0016021=IEA, GO:0005777=ISS} peroxisome organization integral to membrane, peroxisome Human UniProtKB:Q5U4F4 TMEM139 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8IV31 Transmembrane protein 139 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM141 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q96I45 Transmembrane protein 141 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM147 UniProtKB UniProtKB {GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q9BVK8 Transmembrane protein 147 protein 20130413 {GO:0005789=IEA, GO:0016021=IEA} endoplasmic reticulum membrane, integral to membrane Human UniProtKB-SubCell:SL-0097 TMEM14A UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9Y6G1 Transmembrane protein 14A protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM14B UniProtKB UniProtKB {GO:0016020=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q9NUH8 Transmembrane protein 14B protein 20130413 {GO:0016020=IEA, GO:0016021=IEA} integral to membrane, membrane Human UniProtKB-KW:KW-0812 TMEM14C UniProtKB UniProtKB {GO:0031966=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0006783=GO_REF:0000037} Q9P0S9 Transmembrane protein 14C protein 20130413 {GO:0031966=IEA, GO:0016021=IEA, GO:0006783=IEA} heme biosynthetic process integral to membrane, mitochondrial membrane Human UniProtKB-SubCell:SL-0171 TMEM150C UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} B9EJG8 Transmembrane protein 150C protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM159 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q96B96 Promethin protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM160 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q9NX00 Transmembrane protein 160 protein 20130413 {GO:0005739=IEA, GO:0016021=IEA} integral to membrane, mitochondrion Human Ensembl:ENSMUSP00000019302 TMEM161A BHF-UCL UniProtKB {GO:0043066=PMID:16551573, GO:0034644=PMID:16551573, GO:0045739=PMID:16551573, GO:0032526=PMID:16551573, GO:0034599=PMID:16551573, GO:0016021=GO_REF:0000037} Q9NX61 Transmembrane protein 161A protein 20091104 {GO:0043066=IMP, GO:0034644=IDA, GO:0045739=IMP, GO:0032526=IDA, GO:0034599=IDA, GO:0016021=IEA} cellular response to UV, cellular response to oxidative stress, negative regulation of apoptotic process, positive regulation of DNA repair, response to retinoic acid integral to membrane Human TMEM164 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q5U3C3 Transmembrane protein 164 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM165 UniProtKB UniProtKB {GO:0005794=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q9HC07 Transmembrane protein 165 protein 20130413 {GO:0005794=IEA, GO:0016020=IEA, GO:0016021=IEA} Golgi apparatus, integral to membrane, membrane Human UniProtKB-SubCell:SL-0132 TMEM167A UniProtKB UniProtKB {GO:0000139=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q8TBQ9 Protein kish-A protein 20130413 {GO:0000139=IEA, GO:0016021=IEA} Golgi membrane, integral to membrane Human UniProtKB-SubCell:SL-0134 TMEM167B UniProtKB UniProtKB {GO:0000139=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q9NRX6 Protein kish-B protein 20130413 {GO:0000139=IEA, GO:0016021=IEA} Golgi membrane, integral to membrane Human UniProtKB-SubCell:SL-0134 TMEM168 LIFEdb UniProtKB {GO:0030133=GO_REF:0000054, GO:0016021=GO_REF:0000037} Q9H0V1 Transmembrane protein 168 protein 20100607 {GO:0030133=IDA, GO:0016021=IEA} integral to membrane, transport vesicle Human TMEM169 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q96HH4 Transmembrane protein 169 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM170A UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8WVE7 Transmembrane protein 170A protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM171 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8WVE6 Transmembrane protein 171 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM173 BHF-UCL UniProtKB {GO:0005515=PMID:19416887, GO:0048471=GO_REF:0000024, GO:0033160=PMID:18818105, GO:0005886=GO_REF:0000039, GO:0035458=GO_REF:0000019, GO:0005783=GO_REF:0000019, GO:0005741=PMID:18818105, GO:0002218=PMID:18818105, GO:0042993=PMID:18818105, GO:0042803=PMID:22705373, GO:0032092=PMID:18818105, GO:0035438=PMID:22705373, GO:0005829=Reactome:REACT_147901, GO:0051607=PMID:21074459, GO:0045944=PMID:18818105, GO:0061507=GO_REF:0000024, GO:0032481=Reactome:REACT_147841, GO:0031625=GO_REF:0000019, GO:0032608=PMID:19433799, GO:0005794=GO_REF:0000019, GO:0019901=PMID:18818105, GO:0006915=GO_REF:0000037, GO:0071360=PMID:18818105, GO:0045087=Reactome:REACT_6802, GO:0002230=PMID:18818105, GO:0005789=PMID:19433799, GO:0016021=GO_REF:0000037, GO:0008134=PMID:18818105} Q86WV6 Stimulator of interferon genes protein protein 20110225 {GO:0005515=IPI, GO:0048471=ISS, GO:0033160=IDA, GO:0005886=IEA, GO:0035458=IEA, GO:0005783=IEA, GO:0005741=IDA, GO:0002218=IMP, GO:0042993=IDA, GO:0042803=IDA, GO:0032092=IDA, GO:0035438=IDA, GO:0005829=TAS, GO:0051607=IDA, GO:0045944=IDA, GO:0061507=ISS, GO:0032481=TAS, GO:0031625=IEA, GO:0032608=IMP, GO:0005794=IEA, GO:0019901=IDA, GO:0006915=IEA, GO:0071360=IMP, GO:0045087=TAS, GO:0002230=IMP, GO:0005789=IDA, GO:0016021=IEA, GO:0008134=IDA} activation of innate immune response, apoptotic process, cellular response to exogenous dsRNA, cellular response to interferon-beta, defense response to virus, innate immune response, interferon-beta production, positive regulation of defense response to virus by host, positive regulation of protein binding, positive regulation of protein import into nucleus, translocation, positive regulation of transcription factor import into nucleus, positive regulation of transcription from RNA polymerase II promoter, positive regulation of type I interferon production Golgi apparatus, cytosol, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, mitochondrial outer membrane, perinuclear region of cytoplasm, plasma membrane cyclic-GMP-AMP binding, cyclic-di-GMP binding, protein binding, protein homodimerization activity, protein kinase binding, transcription factor binding, ubiquitin protein ligase binding Human TMEM175 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9BSA9 Transmembrane protein 175 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM176A ENSEMBL UniProtKB {GO:0016021=GO_REF:0000037, GO:2001199=GO_REF:0000019} Q96HP8 Transmembrane protein 176A protein 20130413 {GO:0016021=IEA, GO:2001199=IEA} negative regulation of dendritic cell differentiation integral to membrane Human Ensembl:ENSMUSP00000098969 TMEM177 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q53S58 Transmembrane protein 177 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM179B UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q7Z7N9 Transmembrane protein 179B protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM18 UniProtKB UniProtKB {GO:0031965=PMID:18559506, GO:0005737=GO_REF:0000039, GO:0016477=PMID:18559506, GO:0016021=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96B42 Transmembrane protein 18 protein 20100505 {GO:0031965=IDA, GO:0005737=IEA, GO:0016477=IDA, GO:0016021=IEA, GO:0003677=IEA, GO:0006351=IEA} cell migration, transcription, DNA-dependent cytoplasm, integral to membrane, nuclear membrane DNA binding Human TMEM180 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q14CX5 Transmembrane protein 180 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM183A UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8IXX5 Transmembrane protein 183A protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM183B UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q1AE95 Transmembrane protein 183B protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM184A ENSEMBL UniProtKB {GO:0032880=GO_REF:0000019, GO:0051046=GO_REF:0000019, GO:0031901=GO_REF:0000019, GO:0018992=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q6ZMB5 Transmembrane protein 184A protein 20130413 {GO:0032880=IEA, GO:0051046=IEA, GO:0031901=IEA, GO:0018992=IEA, GO:0016021=IEA} germ-line sex determination, regulation of protein localization, regulation of secretion early endosome membrane, integral to membrane Human Ensembl:ENSMUSP00000035399 TMEM184B UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9Y519 Transmembrane protein 184B protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM184C UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9NVA4 Transmembrane protein 184C protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM185B UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9H7F4 Putative transmembrane protein 185B protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM186 LIFEdb UniProtKB {GO:0005739=GO_REF:0000054, GO:0016021=GO_REF:0000037} Q96B77 Transmembrane protein 186 protein 20100607 {GO:0005739=IDA, GO:0016021=IEA} integral to membrane, mitochondrion Human TMEM189 InterPro UniProtKB {GO:0016881=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037} G3V2F7 HCG2044781 protein 20130413 {GO:0016881=IEA, GO:0005789=IEA, GO:0016021=IEA} endoplasmic reticulum membrane, integral to membrane acid-amino acid ligase activity Human InterPro:IPR000608 TMEM19 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q96HH6 Transmembrane protein 19 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM192 UniProtKB UniProtKB {GO:0005770=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0005765=GO_REF:0000039} Q8IY95 Transmembrane protein 192 protein 20130413 {GO:0005770=IEA, GO:0016021=IEA, GO:0005765=IEA} integral to membrane, late endosome, lysosomal membrane Human UniProtKB-SubCell:SL-0152 TMEM194A UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0016021=GO_REF:0000029} O14524 Transmembrane protein 194A protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0016021=NAS} biological_process integral to membrane molecular_function Human TMEM194B UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} A6NFY4 Transmembrane protein 194B protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM199 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8N511 Transmembrane protein 199 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM2 UniProtKB UniProtKB {GO:0007275=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q9UHN6 Transmembrane protein 2 protein 20130413 {GO:0007275=IEA, GO:0016021=IEA} multicellular organismal development integral to membrane Human UniProtKB-KW:KW-0812 TMEM201 UniProtKB UniProtKB {GO:0005637=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q5SNT2 Transmembrane protein 201 protein 20130413 {GO:0005637=IEA, GO:0016021=IEA} integral to membrane, nuclear inner membrane Human UniProtKB-SubCell:SL-0179 TMEM203 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q969S6 Transmembrane protein 203 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM205 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q6UW68 Transmembrane protein 205 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM206 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9H813 Transmembrane protein 206 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM207 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q6UWW9 Transmembrane protein 207 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM209 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q96SK2 Transmembrane protein 209 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM214 UniProtKB UniProtKB {GO:0005881=PMID:23264731, GO:0016021=GO_REF:0000037} Q6NUQ4 Transmembrane protein 214 protein 20130311 {GO:0005881=IDA, GO:0016021=IEA} cytoplasmic microtubule, integral to membrane Human TMEM216 UniProtKB UniProtKB {GO:0005929=PMID:22282472, GO:0042384=PMID:22282472, GO:0005737=GO_REF:0000037, GO:0060271=GO_REF:0000024, GO:0036038=GO_REF:0000024, GO:0005932=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q9P0N5 Transmembrane protein 216 protein 20120228 {GO:0005929=IDA, GO:0042384=IMP, GO:0005737=IEA, GO:0060271=ISS, GO:0036038=ISS, GO:0005932=IEA, GO:0016021=IEA} cilium assembly, cilium morphogenesis TCTN-B9D complex, cilium, cytoplasm, integral to membrane, microtubule basal body Human TMEM222 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9H0R3 Transmembrane protein 222 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM223 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0016021=GO_REF:0000037} A0PJW6 Transmembrane protein 223 protein 20130413 {GO:0005739=IEA, GO:0016021=IEA} integral to membrane, mitochondrion Human Ensembl:ENSMUSP00000010248 TMEM225 UniProtKB UniProtKB {GO:0010923=PMID:19389623, GO:0016021=GO_REF:0000037} Q6GV28 Transmembrane protein 225 protein 20111103 {GO:0010923=IDA, GO:0016021=IEA} negative regulation of phosphatase activity integral to membrane Human TMEM232 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} C9JQI7 Transmembrane protein 232 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM233 UniProtKB UniProtKB {GO:0009607=GO_REF:0000002, GO:0016021=GO_REF:0000037} B4DJY2 Transmembrane protein 233 protein 20130413 {GO:0009607=IEA, GO:0016021=IEA} response to biotic stimulus integral to membrane Human UniProtKB-KW:KW-0812 TMEM237 UniProtKB UniProtKB {GO:0042384=PMID:22152675, GO:0030111=PMID:22152675, GO:0035869=PMID:22152675, GO:0016021=GO_REF:0000037} Q96Q45 Transmembrane protein 237 protein 20120113 {GO:0042384=IMP, GO:0030111=IMP, GO:0035869=IDA, GO:0016021=IEA} cilium assembly, regulation of Wnt receptor signaling pathway ciliary transition zone, integral to membrane Human TMEM241 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q24JQ0 Transmembrane protein 241 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM242 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9NWH2 Transmembrane protein 242 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM25 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016020=GO_REF:0000038, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q86YD3 Transmembrane protein 25 protein 20130413 {GO:0005886=IEA, GO:0016020=IEA, GO:0005576=IEA, GO:0016021=IEA} extracellular region, integral to membrane, membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 TMEM27 UniProtKB UniProtKB {GO:0008241=GO_REF:0000002, GO:0006508=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0008237=GO_REF:0000002} Q9HBJ8 Collectrin protein 20130413 {GO:0008241=IEA, GO:0006508=IEA, GO:0016021=IEA, GO:0008237=IEA} proteolysis integral to membrane metallopeptidase activity, peptidyl-dipeptidase activity Human UniProtKB-KW:KW-0812 TMEM30A UniProtKB UniProtKB {GO:0005515=PMID:21914794, GO:0070863=PMID:21914794, GO:0016020=GO_REF:0000002, GO:0005783=PMID:21914794, GO:0036010=PMID:21914794, GO:0016021=GO_REF:0000037} Q9NV96 Cell cycle control protein 50A protein 20110922 {GO:0005515=IPI, GO:0070863=IDA, GO:0016020=IEA, GO:0005783=IDA, GO:0036010=IMP, GO:0016021=IEA} positive regulation of protein exit from endoplasmic reticulum, protein localization to endosome endoplasmic reticulum, integral to membrane, membrane protein binding Human UniProtKB:Q9P241 TMEM33 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0042470=PMID:17081065, GO:0016021=GO_REF:0000037} P57088 Transmembrane protein 33 protein 20080610 {GO:0008150=ND, GO:0042470=IDA, GO:0016021=IEA} biological_process integral to membrane, melanosome Human TMEM35 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0016023=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037, GO:0005778=GO_REF:0000039} Q53FP2 Transmembrane protein 35 protein 20120517 {GO:0003674=ND, GO:0008150=ND, GO:0016023=IEA, GO:0005575=ND, GO:0016021=IEA, GO:0005778=IEA} biological_process cellular_component, cytoplasmic membrane-bounded vesicle, integral to membrane, peroxisomal membrane molecular_function Human TMEM37 UniProtKB UniProtKB {GO:0005262=GO_REF:0000037, GO:0005244=GO_REF:0000037, GO:0016021=GO_REF:0000037} Q8WXS4 Voltage-dependent calcium channel gamma-like subunit protein 20130413 {GO:0005262=IEA, GO:0005244=IEA, GO:0016021=IEA} integral to membrane calcium channel activity, voltage-gated ion channel activity Human UniProtKB-KW:KW-0812 TMEM38B BHF-UCL UniProtKB {GO:0031965=PMID:19095005, GO:0005261=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0033017=PMID:19095005, GO:0005267=PMID:19095005, GO:0016021=GO_REF:0000037, GO:0015672=GO_REF:0000002} Q9NVV0 Trimeric intracellular cation channel type B protein 20090203 {GO:0031965=NAS, GO:0005261=IEA, GO:0016020=IEA, GO:0033017=NAS, GO:0005267=TAS, GO:0016021=IEA, GO:0015672=IEA} monovalent inorganic cation transport integral to membrane, membrane, nuclear membrane, sarcoplasmic reticulum membrane cation channel activity, potassium channel activity Human TMEM39A UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9NV64 Transmembrane protein 39A protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM39B UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9GZU3 Transmembrane protein 39B protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM41A UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q96HV5 Transmembrane protein 41A protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM41B UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q5BJD5 Transmembrane protein 41B protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM43 LIFEdb UniProtKB {GO:0005794=GO_REF:0000054, GO:0005783=GO_REF:0000039, GO:0005637=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q9BTV4 Transmembrane protein 43 protein 20100607 {GO:0005794=IDA, GO:0005783=IEA, GO:0005637=IEA, GO:0016021=IEA} Golgi apparatus, endoplasmic reticulum, integral to membrane, nuclear inner membrane Human TMEM44 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q2T9K0 Transmembrane protein 44 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM45A UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9NWC5 Transmembrane protein 45A protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM45B UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q96B21 Transmembrane protein 45B protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM48 UniProtKB UniProtKB {GO:0031965=GO_REF:0000039, GO:0005643=PMID:16600873, GO:0031081=PMID:16600873, GO:0017056=PMID:16600873, GO:0051028=GO_REF:0000037, GO:0016021=GO_REF:0000038, GO:0015031=PMID:16600873, GO:0051292=PMID:16600873} Q9BTX1 Nucleoporin NDC1 protein 20060525 {GO:0031965=IEA, GO:0005643=IDA, GO:0031081=IMP, GO:0017056=IMP, GO:0051028=IEA, GO:0016021=IEA, GO:0015031=NAS, GO:0051292=IMP} mRNA transport, nuclear pore complex assembly, nuclear pore distribution, protein transport integral to membrane, nuclear membrane, nuclear pore structural constituent of nuclear pore Human TMEM5 PINC UniProtKB {GO:0005887=PMID:10072769, GO:0016021=GO_REF:0000038} Q9Y2B1 Transmembrane protein 5 protein 20030904 {GO:0005887=TAS, GO:0016021=IEA} integral to membrane, integral to plasma membrane Human TMEM50A LIFEdb UniProtKB {GO:0005783=GO_REF:0000054, GO:0016021=GO_REF:0000037} O95807 Transmembrane protein 50A protein 20100607 {GO:0005783=IDA, GO:0016021=IEA} endoplasmic reticulum, integral to membrane Human TMEM51 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9NW97 Transmembrane protein 51 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM53 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q6P2H8 Transmembrane protein 53 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM54 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} Q969K7 Transmembrane protein 54 protein 20110929 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND, GO:0016021=IEA} biological_process cellular_component, integral to membrane molecular_function Human TMEM55A UniProtKB UniProtKB {GO:0016787=GO_REF:0000037, GO:0031902=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0005765=GO_REF:0000039} Q8N4L2 Transmembrane protein 55A protein 20130413 {GO:0016787=IEA, GO:0031902=IEA, GO:0016021=IEA, GO:0005765=IEA} integral to membrane, late endosome membrane, lysosomal membrane hydrolase activity Human UniProtKB-SubCell:SL-0151 TMEM55B UniProtKB UniProtKB {GO:0016787=GO_REF:0000037, GO:0031902=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0005765=GO_REF:0000039} Q86T03 Transmembrane protein 55B protein 20130413 {GO:0016787=IEA, GO:0031902=IEA, GO:0016021=IEA, GO:0005765=IEA} integral to membrane, late endosome membrane, lysosomal membrane hydrolase activity Human UniProtKB-SubCell:SL-0151 TMEM56 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} Q96MV1 Transmembrane protein 56 protein 20090501 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND, GO:0016021=IEA} biological_process cellular_component, integral to membrane molecular_function Human TMEM57 BHF-UCL UniProtKB {GO:0044306=PMID:15255972, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0030424=GO_REF:0000039, GO:0031965=PMID:15255972, GO:0007420=GO_REF:0000019, GO:0044456=GO_REF:0000019, GO:0045202=PMID:15255972, GO:0005634=PMID:12459264, GO:0016021=GO_REF:0000037} Q8N5G2 Macoilin protein 20101118 {GO:0044306=ISS, GO:0003674=ND, GO:0008150=ND, GO:0030424=IEA, GO:0031965=ISS, GO:0007420=IEA, GO:0044456=IEA, GO:0045202=ISS, GO:0005634=ISS, GO:0016021=IEA} biological_process, brain development axon, integral to membrane, neuron projection terminus, nuclear membrane, nucleus, synapse, synapse part molecular_function Human UniProtKB:Q7TQE6 TMEM59 UniProtKB UniProtKB {GO:0005515=PMID:23376921, GO:0005886=GO_REF:0000039, GO:0000139=GO_REF:0000039, GO:0004175=GO_REF:0000019, GO:0005770=PMID:23376921, GO:0031902=GO_REF:0000039, GO:0006914=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005765=GO_REF:0000039, GO:0005764=PMID:23376921, GO:0010508=PMID:23376921} Q9BXS4 Transmembrane protein 59 protein 20130222 {GO:0005515=IPI, GO:0005886=IEA, GO:0000139=IEA, GO:0004175=IEA, GO:0005770=IDA, GO:0031902=IEA, GO:0006914=IEA, GO:0016021=IEA, GO:0005765=IEA, GO:0005764=IDA, GO:0010508=IMP} autophagy, positive regulation of autophagy Golgi membrane, integral to membrane, late endosome, late endosome membrane, lysosomal membrane, lysosome, plasma membrane endopeptidase activity, protein binding Human UniProtKB:Q676U5 TMEM59L PINC UniProtKB {GO:0016020=PMID:10527841, GO:0000139=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q9UK28 Transmembrane protein 59-like protein 20030904 {GO:0016020=TAS, GO:0000139=IEA, GO:0016021=IEA} Golgi membrane, integral to membrane, membrane Human TMEM62 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q0P6H9 Transmembrane protein 62 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM63A UniProtKB UniProtKB {GO:0000166=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005765=PMID:20957757} O94886 Transmembrane protein 63A protein 20101207 {GO:0000166=IEA, GO:0016021=IEA, GO:0005765=IDA} integral to membrane, lysosomal membrane nucleotide binding Human TMEM63B UniProtKB UniProtKB {GO:0016020=GO_REF:0000002, GO:0000166=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q5T3F8 Transmembrane protein 63B protein 20130413 {GO:0016020=IEA, GO:0000166=IEA, GO:0016021=IEA} integral to membrane, membrane nucleotide binding Human UniProtKB-KW:KW-0812 TMEM64 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q6YI46 Transmembrane protein 64 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM65 ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q6PI78 Transmembrane protein 65 protein 20130413 {GO:0005739=IEA, GO:0016021=IEA} integral to membrane, mitochondrion Human Ensembl:ENSMUSP00000071984 TMEM66 UniProtKB UniProtKB {GO:0005515=PMID:22464749, GO:0030176=PMID:22464749, GO:0015279=PMID:22464749, GO:2001256=PMID:22464749} Q96BY9 Store-operated calcium entry-associated regulatory factor protein 20120430 {GO:0005515=IPI, GO:0030176=IDA, GO:0015279=IDA, GO:2001256=IDA} regulation of store-operated calcium entry integral to endoplasmic reticulum membrane protein binding, store-operated calcium channel activity Human UniProtKB:Q13586 TMEM67 UniProtKB UniProtKB {GO:0005515=PMID:19815549, GO:0005813=PMID:17185389, GO:0060170=PMID:17185389, GO:0010826=PMID:19515853, GO:0036038=GO_REF:0000024, GO:0030433=PMID:19815549, GO:0042384=PMID:19515853, GO:0031005=PMID:22121117, GO:0060271=GO_REF:0000024, GO:0005789=PMID:19815549, GO:0016021=GO_REF:0000037, GO:0005932=GO_REF:0000039, GO:0051082=PMID:19815549, GO:0030659=PMID:19815549} Q5HYA8 Meckelin protein 20120523 {GO:0005515=IPI, GO:0005813=IDA, GO:0060170=IDA, GO:0010826=IMP, GO:0036038=ISS, GO:0030433=IMP, GO:0042384=IMP, GO:0031005=IPI, GO:0060271=ISS, GO:0005789=IDA, GO:0016021=IEA, GO:0005932=IEA, GO:0051082=IPI, GO:0030659=IDA} ER-associated protein catabolic process, cilium assembly, cilium morphogenesis, negative regulation of centrosome duplication TCTN-B9D complex, centrosome, cilium membrane, cytoplasmic vesicle membrane, endoplasmic reticulum membrane, integral to membrane, microtubule basal body filamin binding, protein binding, unfolded protein binding Human UniProtKB:P21333 TMEM68 UniProtKB UniProtKB {GO:0016746=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q96MH6 Transmembrane protein 68 protein 20130413 {GO:0016746=IEA, GO:0016021=IEA} integral to membrane transferase activity, transferring acyl groups Human UniProtKB-KW:KW-0812 TMEM70 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0033615=PMID:18953340, GO:0032592=PMID:18953340, GO:0005743=GO_REF:0000039} Q9BUB7 Transmembrane protein 70, mitochondrial protein 20090120 {GO:0003674=ND, GO:0033615=IMP, GO:0032592=IDA, GO:0005743=IEA} mitochondrial proton-transporting ATP synthase complex assembly integral to mitochondrial membrane, mitochondrial inner membrane molecular_function Human TMEM86A UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8N2M4 Lysoplasmalogenase-like protein TMEM86A protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM86B UniProtKB UniProtKB {GO:0044444=PMID:21515882, GO:0016020=PMID:21515882, GO:0047409=PMID:21515882, GO:0046485=PMID:21515882, GO:0047408=PMID:21515882, GO:0016021=GO_REF:0000037} Q8N661 Lysoplasmalogenase protein 20110520 {GO:0044444=IDA, GO:0016020=IDA, GO:0047409=IDA, GO:0046485=IDA, GO:0047408=IDA, GO:0016021=IEA} ether lipid metabolic process cytoplasmic part, integral to membrane, membrane alkenylglycerophosphocholine hydrolase activity, alkenylglycerophosphoethanolamine hydrolase activity Human TMEM87A UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8NBN3 Transmembrane protein 87A protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMEM8B HGNC UniProtKB {GO:0005515=PMID:15498789, GO:0005739=GO_REF:0000039, GO:0007346=PMID:15498789, GO:0007160=PMID:15498789, GO:0009986=PMID:15498789, GO:0005886=PMID:15498789, GO:0005783=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0040008=GO_REF:0000037} A6NDV4 Transmembrane protein 8B protein 20050914 {GO:0005515=IPI, GO:0005739=IEA, GO:0007346=TAS, GO:0007160=IMP, GO:0009986=IDA, GO:0005886=IDA, GO:0005783=IEA, GO:0005634=IEA, GO:0016021=IEA, GO:0040008=IEA} cell-matrix adhesion, regulation of growth, regulation of mitotic cell cycle cell surface, endoplasmic reticulum, integral to membrane, mitochondrion, nucleus, plasma membrane protein binding Human TMEM9 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005770=PMID:12359240, GO:0031902=GO_REF:0000039, GO:0006810=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005765=GO_REF:0000039, GO:0005764=PMID:12359240} Q9P0T7 Transmembrane protein 9 protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0005770=IDA, GO:0031902=IEA, GO:0006810=IEA, GO:0016021=IEA, GO:0005765=IEA, GO:0005764=IDA} biological_process, transport integral to membrane, late endosome, late endosome membrane, lysosomal membrane, lysosome molecular_function Human TMEM97 HPA UniProtKB {GO:0005515=PMID:19583955, GO:0005791=PMID:19583955, GO:0042632=PMID:19583955, GO:0005737=GO_REF:0000052, GO:0031965=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0016021=GO_REF:0000037, GO:0001558=PMID:7694637, GO:0005764=PMID:19583955} Q86XC5 Transmembrane protein 97 protein 20111111 {GO:0005515=IPI, GO:0005791=IDA, GO:0042632=IDA, GO:0005737=IDA, GO:0031965=IDA, GO:0005886=IDA, GO:0016021=IEA, GO:0001558=NAS, GO:0005764=IDA} cholesterol homeostasis, regulation of cell growth cytoplasm, integral to membrane, lysosome, nuclear membrane, plasma membrane, rough endoplasmic reticulum protein binding Human TMEM98 LIFEdb UniProtKB {GO:0005783=GO_REF:0000054, GO:0016021=GO_REF:0000037} Q9Y2Y6 Transmembrane protein 98 protein 20100607 {GO:0005783=IDA, GO:0016021=IEA} endoplasmic reticulum, integral to membrane Human TMEM9B GOC UniProtKB {GO:0007165=PMID:12761501, GO:0004871=PMID:12761501, GO:0016021=GO_REF:0000037, GO:0043123=PMID:12761501} Q9NQ34 Transmembrane protein 9B protein 20130413 {GO:0007165=IMP, GO:0004871=IMP, GO:0016021=IEA, GO:0043123=IMP} positive regulation of I-kappaB kinase/NF-kappaB cascade, signal transduction integral to membrane signal transducer activity Human TMF1 HPA UniProtKB {GO:0005515=PMID:20195357, GO:0003712=PMID:10428808, GO:0006355=GO_REF:0000037, GO:0005794=GO_REF:0000052, GO:0006366=PMID:1409643, GO:0000139=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037} P82094 TATA element modulatory factor protein 20080205 {GO:0005515=IPI, GO:0003712=TAS, GO:0006355=IEA, GO:0005794=IDA, GO:0006366=TAS, GO:0000139=IEA, GO:0005634=IEA, GO:0003677=IEA} regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter Golgi apparatus, Golgi membrane, nucleus DNA binding, protein binding, transcription cofactor activity Human TMLHE Reactome UniProtKB {GO:0050353=Reactome:REACT_1814, GO:0034641=Reactome:REACT_13, GO:0031418=GO_REF:0000002, GO:0005506=GO_REF:0000002, GO:0005759=Reactome:REACT_1814, GO:0045329=Reactome:REACT_2125, GO:0044281=Reactome:REACT_111217, GO:0016702=GO_REF:0000019} Q9NVH6 Trimethyllysine dioxygenase, mitochondrial protein 20100219 {GO:0050353=TAS, GO:0034641=TAS, GO:0031418=IEA, GO:0005506=IEA, GO:0005759=TAS, GO:0045329=TAS, GO:0044281=TAS, GO:0016702=IEA} carnitine biosynthetic process, cellular nitrogen compound metabolic process, small molecule metabolic process mitochondrial matrix L-ascorbic acid binding, iron ion binding, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, trimethyllysine dioxygenase activity Human TMOD1 InterPro UniProtKB {GO:0008344=GO_REF:0000019, GO:0030049=Reactome:REACT_16969, GO:0008180=PMID:18850735, GO:0016020=GO_REF:0000019, GO:0030239=GO_REF:0000019, GO:0030863=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0005856=GO_REF:0000002, GO:0030016=GO_REF:0000019, GO:0005523=GO_REF:0000002, GO:0005829=Reactome:REACT_17057} Q5T7W3 Tropomodulin-1 protein 20130413 {GO:0008344=IEA, GO:0030049=TAS, GO:0008180=IDA, GO:0016020=IEA, GO:0030239=IEA, GO:0030863=IEA, GO:0003779=IEA, GO:0005856=IEA, GO:0030016=IEA, GO:0005523=IEA, GO:0005829=TAS} adult locomotory behavior, muscle filament sliding, myofibril assembly cortical cytoskeleton, cytoskeleton, cytosol, membrane, myofibril, signalosome actin binding, tropomyosin binding Human InterPro:IPR004934 TMOD2 PINC UniProtKB {GO:0005737=GO_REF:0000037, GO:0045745=GO_REF:0000019, GO:0007611=GO_REF:0000019, GO:0003779=GO_REF:0000019, GO:0005523=GO_REF:0000019, GO:0005856=GO_REF:0000039, GO:0007399=PMID:10662549, GO:0030426=GO_REF:0000019, GO:0007270=GO_REF:0000019} Q9NZR1 Tropomodulin-2 protein 20030904 {GO:0005737=IEA, GO:0045745=IEA, GO:0007611=IEA, GO:0003779=IEA, GO:0005523=IEA, GO:0005856=IEA, GO:0007399=TAS, GO:0030426=IEA, GO:0007270=IEA} learning or memory, nervous system development, neuron-neuron synaptic transmission, positive regulation of G-protein coupled receptor protein signaling pathway cytoplasm, cytoskeleton, growth cone actin binding, tropomyosin binding Human TMOD3 ENSEMBL UniProtKB {GO:0005865=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0005856=GO_REF:0000002, GO:0005523=GO_REF:0000019} Q9NYL9 Tropomodulin-3 protein 20130413 {GO:0005865=IEA, GO:0003779=IEA, GO:0005856=IEA, GO:0005523=IEA} cytoskeleton, striated muscle thin filament actin binding, tropomyosin binding Human Ensembl:ENSMUSP00000072087 TMOD4 PINC UniProtKB {GO:0006936=PMID:10662549, GO:0005865=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0005856=GO_REF:0000002, GO:0005523=GO_REF:0000019} Q9NZQ9 Tropomodulin-4 protein 20050308 {GO:0006936=TAS, GO:0005865=IEA, GO:0003779=IEA, GO:0005856=IEA, GO:0005523=IEA} muscle contraction cytoskeleton, striated muscle thin filament actin binding, tropomyosin binding Human TMPO IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0006355=GO_REF:0000019, GO:0005637=GO_REF:0000039, GO:0005634=PMID:8530026, GO:0016021=GO_REF:0000037, GO:0005635=PMID:8530026, GO:0000785=PMID:17284516, GO:0003677=GO_REF:0000037, GO:0005521=PMID:8530026} P42167 Lamina-associated polypeptide 2, isoforms beta/gamma protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0005637=IEA, GO:0005634=TAS, GO:0016021=IEA, GO:0005635=TAS, GO:0000785=IDA, GO:0003677=IEA, GO:0005521=TAS} regulation of transcription, DNA-dependent chromatin, integral to membrane, nuclear envelope, nuclear inner membrane, nucleus DNA binding, lamin binding, protein binding Human UniProtKB:P16333 TMPRSS11A UniProtKB UniProtKB {GO:0007049=GO_REF:0000037, GO:0004252=GO_REF:0000002, GO:0005887=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0005576=GO_REF:0000002} Q6ZMR5 Transmembrane protease serine 11A protein 20130413 {GO:0007049=IEA, GO:0004252=IEA, GO:0005887=IEA, GO:0006508=IEA, GO:0005576=IEA} cell cycle, proteolysis extracellular region, integral to plasma membrane serine-type endopeptidase activity Human UniProtKB-KW:KW-0131 TMPRSS13 UniProtKB UniProtKB {GO:0016020=GO_REF:0000002, GO:0004252=PMID:11267681, GO:0006508=GO_REF:0000029, GO:0016021=PMID:11267681, GO:0005044=GO_REF:0000002} Q9BYE2 Transmembrane protease serine 13 protein 20021106 {GO:0016020=IEA, GO:0004252=NAS, GO:0006508=NAS, GO:0016021=NAS, GO:0005044=IEA} proteolysis integral to membrane, membrane scavenger receptor activity, serine-type endopeptidase activity Human TMPRSS15 PINC UniProtKB {GO:0005903=PMID:8052624, GO:0004252=GO_REF:0000002, GO:0006508=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005044=GO_REF:0000002} P98073 Enteropeptidase protein 20030904 {GO:0005903=TAS, GO:0004252=IEA, GO:0006508=IEA, GO:0016021=IEA, GO:0005044=IEA} proteolysis brush border, integral to membrane scavenger receptor activity, serine-type endopeptidase activity Human TMPRSS2 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0004252=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0005887=PMID:9325052, GO:0006508=GO_REF:0000037, GO:0008236=PMID:9325052, GO:0005576=GO_REF:0000039, GO:0005044=GO_REF:0000002} O15393 Transmembrane protease serine 2 protein 20081203 {GO:0005737=IDA, GO:0005886=IDA, GO:0004252=IEA, GO:0016020=IEA, GO:0005887=TAS, GO:0006508=IEA, GO:0008236=TAS, GO:0005576=IEA, GO:0005044=IEA} proteolysis cytoplasm, extracellular region, integral to plasma membrane, membrane, plasma membrane scavenger receptor activity, serine-type endopeptidase activity, serine-type peptidase activity Human TMPRSS3 UniProtKB UniProtKB {GO:0016020=GO_REF:0000002, GO:0004252=GO_REF:0000002, GO:0005783=PMID:16780588, GO:0007605=GO_REF:0000019, GO:0006883=PMID:12393794, GO:0005789=PMID:12393794, GO:0043025=GO_REF:0000019, GO:0006508=GO_REF:0000038, GO:0016021=GO_REF:0000038, GO:0017080=PMID:12393794, GO:0005044=GO_REF:0000002} Q5USC7 Transmembrane protease serine 3 protein 20130413 {GO:0016020=IEA, GO:0004252=IEA, GO:0005783=IDA, GO:0007605=IEA, GO:0006883=IDA, GO:0005789=IDA, GO:0043025=IEA, GO:0006508=IEA, GO:0016021=IEA, GO:0017080=IDA, GO:0005044=IEA} cellular sodium ion homeostasis, proteolysis, sensory perception of sound endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, membrane, neuronal cell body scavenger receptor activity, serine-type endopeptidase activity, sodium channel regulator activity Human UniProtKB-KW:KW-0812 TMPRSS6 UniProtKB UniProtKB {GO:0005515=PMID:19357398, GO:0035556=PMID:12149247, GO:0005886=PMID:19357398, GO:0004252=PMID:12149247, GO:0030198=PMID:12149247, GO:0006508=PMID:12149247, GO:0016021=PMID:12149247, GO:0001525=PMID:12149247, GO:0055072=PMID:18408718, GO:0042730=PMID:12149247} Q8IU80 Transmembrane protease serine 6 protein 20120823 {GO:0005515=IPI, GO:0035556=NAS, GO:0005886=IDA, GO:0004252=IDA, GO:0030198=NAS, GO:0006508=IDA, GO:0016021=IDA, GO:0001525=NAS, GO:0055072=IMP, GO:0042730=IDA} angiogenesis, extracellular matrix organization, fibrinolysis, intracellular signal transduction, iron ion homeostasis, proteolysis integral to membrane, plasma membrane protein binding, serine-type endopeptidase activity Human TMSB10 UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0042989=GO_REF:0000002, GO:0030036=GO_REF:0000002, GO:0003779=GO_REF:0000037, GO:0005856=GO_REF:0000039} P63313 Thymosin beta-10 protein 20130413 {GO:0005737=IEA, GO:0042989=IEA, GO:0030036=IEA, GO:0003779=IEA, GO:0005856=IEA} actin cytoskeleton organization, sequestering of actin monomers cytoplasm, cytoskeleton actin binding Human UniProtKB-SubCell:SL-0090 TMSB4X Reactome UniProtKB {GO:0042989=GO_REF:0000002, GO:0030036=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0030168=Reactome:REACT_798, GO:0031093=Reactome:REACT_21351, GO:0005576=Reactome:REACT_21351, GO:0003779=GO_REF:0000037, GO:0005856=GO_REF:0000039} P62328 Thymosin beta-4 protein 20080513 {GO:0042989=IEA, GO:0030036=IEA, GO:0007596=TAS, GO:0002576=TAS, GO:0030168=TAS, GO:0031093=TAS, GO:0005576=TAS, GO:0003779=IEA, GO:0005856=IEA} actin cytoskeleton organization, blood coagulation, platelet activation, platelet degranulation, sequestering of actin monomers cytoskeleton, extracellular region, platelet alpha granule lumen actin binding Human TMSB4Y PINC UniProtKB {GO:0030334=GO_REF:0000019, GO:0042989=GO_REF:0000002, GO:0030036=GO_REF:0000002, GO:0008064=PMID:8838802, GO:0005634=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0005856=GO_REF:0000039, GO:0005829=GO_REF:0000019} O14604 Thymosin beta-4, Y-chromosomal protein 20030904 {GO:0030334=IEA, GO:0042989=IEA, GO:0030036=IEA, GO:0008064=TAS, GO:0005634=IEA, GO:0003779=IEA, GO:0005856=IEA, GO:0005829=IEA} actin cytoskeleton organization, regulation of actin polymerization or depolymerization, regulation of cell migration, sequestering of actin monomers cytoskeleton, cytosol, nucleus actin binding Human TMTC2 LIFEdb UniProtKB {GO:0005783=GO_REF:0000054, GO:0016021=GO_REF:0000037} Q8N394 Transmembrane and TPR repeat-containing protein 2 protein 20100607 {GO:0005783=IDA, GO:0016021=IEA} endoplasmic reticulum, integral to membrane Human TMTC3 ENSEMBL UniProtKB {GO:0048747=GO_REF:0000019, GO:0010468=GO_REF:0000019, GO:0048286=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0009791=GO_REF:0000019, GO:0060447=GO_REF:0000019} Q6ZXV5 Transmembrane and TPR repeat-containing protein 3 protein 20130413 {GO:0048747=IEA, GO:0010468=IEA, GO:0048286=IEA, GO:0016021=IEA, GO:0009791=IEA, GO:0060447=IEA} bud outgrowth involved in lung branching, lung alveolus development, muscle fiber development, post-embryonic development, regulation of gene expression integral to membrane Human Ensembl:ENSMUSP00000061470 TMTC4 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q5T4D3 Transmembrane and TPR repeat-containing protein 4 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMUB1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0016021=GO_REF:0000037} Q9BVT8 Transmembrane and ubiquitin-like domain-containing protein 1 protein 20101115 {GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0016021=IEA} cytoplasm, integral to membrane, nucleolus, nucleus Human TMUB2 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q71RG4 Transmembrane and ubiquitin-like domain-containing protein 2 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TMX1 HPA UniProtKB {GO:0043066=PMID:11152479, GO:0005783=GO_REF:0000052, GO:0008283=PMID:11152479, GO:0030612=PMID:11152479, GO:0006950=PMID:11152479, GO:0015036=PMID:11152479, GO:0006888=PMID:11152479, GO:0006260=PMID:11152479, GO:0007165=PMID:11152479, GO:0045321=PMID:11152479, GO:0005789=PMID:11152479, GO:0045454=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0022900=GO_REF:0000037, GO:0045893=PMID:11152479, GO:0045927=PMID:11152479} Q9H3N1 Thioredoxin-related transmembrane protein 1 protein 20101115 {GO:0043066=IDA, GO:0005783=IDA, GO:0008283=NAS, GO:0030612=NAS, GO:0006950=NAS, GO:0015036=IDA, GO:0006888=TAS, GO:0006260=NAS, GO:0007165=NAS, GO:0045321=NAS, GO:0005789=IDA, GO:0045454=IEA, GO:0016021=IEA, GO:0022900=IEA, GO:0045893=NAS, GO:0045927=NAS} DNA replication, ER to Golgi vesicle-mediated transport, cell proliferation, cell redox homeostasis, electron transport chain, leukocyte activation, negative regulation of apoptotic process, positive regulation of growth, positive regulation of transcription, DNA-dependent, response to stress, signal transduction endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane arsenate reductase (thioredoxin) activity, disulfide oxidoreductase activity Human TMX2 BHF-UCL UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0045454=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037} Q9Y320 Thioredoxin-related transmembrane protein 2 protein 20110707 {GO:0003674=ND, GO:0008150=ND, GO:0045454=IEA, GO:0005575=ND, GO:0016021=IEA} biological_process, cell redox homeostasis cellular_component, integral to membrane molecular_function Human TMX3 MGI UniProtKB {GO:0009986=PMID:19995400, GO:0006662=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0015035=GO_REF:0000002, GO:0003756=GO_REF:0000003, GO:0009055=GO_REF:0000002, GO:0045454=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0016853=GO_REF:0000038} Q96JJ7 Protein disulfide-isomerase TMX3 protein 20120926 {GO:0009986=IDA, GO:0006662=IEA, GO:0005789=IEA, GO:0015035=IEA, GO:0003756=IEA, GO:0009055=IEA, GO:0045454=IEA, GO:0016021=IEA, GO:0016853=IEA} cell redox homeostasis, glycerol ether metabolic process cell surface, endoplasmic reticulum membrane, integral to membrane electron carrier activity, isomerase activity, protein disulfide isomerase activity, protein disulfide oxidoreductase activity Human TMX4 UniProtKB UniProtKB {GO:0045454=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0022900=GO_REF:0000037} Q9H1E5 Thioredoxin-related transmembrane protein 4 protein 20130413 {GO:0045454=IEA, GO:0016021=IEA, GO:0022900=IEA} cell redox homeostasis, electron transport chain integral to membrane Human UniProtKB-KW:KW-0249 TNC BHF-UCL UniProtKB {GO:0008284=GO_REF:0000019, GO:0060740=GO_REF:0000019, GO:0009611=PMID:16891397, GO:0005576=Reactome:REACT_13633, GO:0005614=GO_REF:0000019, GO:0005604=GO_REF:0000019, GO:0010628=GO_REF:0000019, GO:0031012=PMID:22261194, GO:0007528=GO_REF:0000019, GO:0014012=GO_REF:0000019, GO:0007155=GO_REF:0000037, GO:0060739=GO_REF:0000019, GO:0045545=PMID:8769660} P24821 Tenascin protein 20120228 {GO:0008284=IEA, GO:0060740=IEA, GO:0009611=IEP, GO:0005576=TAS, GO:0005614=IEA, GO:0005604=IEA, GO:0010628=IEA, GO:0031012=ISS, GO:0007528=IEA, GO:0014012=IEA, GO:0007155=IEA, GO:0060739=IEA, GO:0045545=IPI} cell adhesion, mesenchymal-epithelial cell signaling involved in prostate gland development, neuromuscular junction development, peripheral nervous system axon regeneration, positive regulation of cell proliferation, positive regulation of gene expression, prostate gland epithelium morphogenesis, response to wounding basement membrane, extracellular matrix, extracellular region, interstitial matrix syndecan binding colocalizes_with Human UniProtKB:Q29116 TNF BHF-UCL UniProtKB {GO:0032755=GO_REF:0000019, GO:0005515=PMID:21784977, GO:0071677=PMID:21319131, GO:0009651=PMID:18355445, GO:0044212=PMID:17350185, GO:0050830=GO_REF:0000019, GO:0046330=GO_REF:0000019, GO:0001819=PMID:17922812, GO:0005615=PMID:10443688, GO:0031622=GO_REF:0000024, GO:0046325=GO_REF:0000019, GO:0044130=GO_REF:0000019, GO:0045071=PMID:10490959, GO:0000060=PMID:16280327, GO:0010940=PMID:16507998, GO:0009986=PMID:18355445, GO:0045840=GO_REF:0000019, GO:0001891=GO_REF:0000024, GO:0071316=PMID:18676776, GO:0005125=PMID:10748004, GO:0005887=PMID:18355445, GO:0045080=PMID:10490959, GO:0050995=PMID:19032770, GO:0050715=PMID:10443688, GO:0010693=GO_REF:0000019, GO:0000187=PMID:10748004, GO:0033138=PMID:17389591, GO:0051091=PMID:10748004, GO:0000185=PMID:15310755, GO:0006954=PMID:10748004, GO:0051092=PMID:20551324, GO:0060664=GO_REF:0000019, GO:0006959=GO_REF:0000019, GO:0006006=GO_REF:0000019, GO:0001775=GO_REF:0000019, GO:0070265=PMID:11101870, GO:0042493=GO_REF:0000019, GO:0045672=PMID:17888176, GO:0051533=PMID:16803872, GO:0048566=PMID:20875417, GO:0045670=GO_REF:0000019, GO:0009615=PMID:10490959, GO:0048661=PMID:16518841, GO:0010888=PMID:16464856, GO:0051222=PMID:15310755, GO:2000343=PMID:20551324, GO:0009612=GO_REF:0000019, GO:0051023=GO_REF:0000019, GO:0045994=GO_REF:0000019, GO:0045668=GO_REF:0000019, GO:0050796=PMID:8383325, GO:0032800=PMID:10443688, GO:0016021=GO_REF:0000019, GO:0019722=GO_REF:0000019, GO:0045599=PMID:16464856, GO:0032715=PMID:10443688, GO:0002020=PMID:12777399, GO:0050901=PMID:10820279, GO:0042802=PMID:14512626, GO:0030730=PMID:19032770, GO:0043525=GO_REF:0000019, GO:0030198=GO_REF:0000019, GO:0061048=PMID:17350185, GO:0034116=PMID:20551324, GO:0009887=GO_REF:0000019, GO:0070374=PMID:18606301, GO:0043123=PMID:17922812, GO:0043122=PMID:10748004, GO:0032729=GO_REF:0000019, GO:0005164=PMID:14512626, GO:0002876=GO_REF:0000019, GO:0045416=PMID:20551324, GO:0051384=PMID:10443688, GO:0000122=GO_REF:0000019, GO:0032722=PMID:10490959, GO:0043242=PMID:17389591, GO:0033209=PMID:10748004, GO:0051798=GO_REF:0000019, GO:0050806=GO_REF:0000019, GO:0045123=GO_REF:0000019, GO:0045121=PMID:17010968, GO:0045893=PMID:14512626, GO:0045892=PMID:17350185, GO:0009897=GO_REF:0000024, GO:0008625=PMID:18676776, GO:0071803=PMID:15220135, GO:0042346=PMID:17922812, GO:0051897=GO_REF:0000019, GO:0060559=PMID:1690216, GO:0002439=PMID:14512626, GO:0051044=PMID:18373975, GO:0008285=GO_REF:0000019, GO:0060693=GO_REF:0000019, GO:0005886=Reactome:REACT_2175, GO:0060555=PMID:11101870, GO:0060557=PMID:1690216, GO:0006927=PMID:3883195, GO:0045429=PMID:8383325, GO:0002740=PMID:10443688, GO:0002925=GO_REF:0000019, GO:0002037=GO_REF:0000019, GO:0031334=PMID:12813029, GO:0071230=GO_REF:0000019, GO:0043406=PMID:12813029, GO:0043243=PMID:12813029, GO:0045944=PMID:16803872, GO:0043507=PMID:17389591, GO:0001666=GO_REF:0000019, GO:0014823=GO_REF:0000019, GO:0043066=PMID:10666185, GO:0043065=PMID:21319131, GO:0006919=PMID:14512626, GO:0030316=GO_REF:0000019, GO:0007254=GO_REF:0000019, GO:0006915=Reactome:REACT_578, GO:0006917=PMID:18202225, GO:0097190=PMID:10521396, GO:0003009=GO_REF:0000019, GO:0001934=PMID:10748004, GO:0001932=GO_REF:0000019, GO:0055037=GO_REF:0000024} P01375 Tumor necrosis factor protein 20120503 {GO:0032755=IEA, GO:0005515=IPI, GO:0071677=NAS, GO:0009651=TAS, GO:0044212=IDA, GO:0050830=IEA, GO:0046330=IEA, GO:0001819=IDA, GO:0005615=IDA, GO:0031622=ISS, GO:0046325=IEA, GO:0044130=IEA, GO:0045071=IDA, GO:0000060=IDA, GO:0010940=TAS, GO:0009986=IDA, GO:0045840=IEA, GO:0001891=ISS, GO:0071316=IDA, GO:0005125=IDA, GO:0005887=IDA, GO:0045080=IDA, GO:0050995=IDA, GO:0050715=IDA, GO:0010693=IEA, GO:0000187=IDA, GO:0033138=IDA, GO:0051091=IDA, GO:0000185=IDA, GO:0006954=IDA, GO:0051092=IDA, GO:0060664=IEA, GO:0006959=IEA, GO:0006006=IEA, GO:0001775=IEA, GO:0070265=IDA, GO:0042493=IEA, GO:0045672=IDA, GO:0051533=IDA, GO:0048566=IEP, GO:0045670=IEA, GO:0009615=IDA, GO:0048661=IDA, GO:0010888=NAS, GO:0051222=IDA, GO:2000343=IDA, GO:0009612=IEA, GO:0051023=IEA, GO:0045994=IEA, GO:0045668=IEA, GO:0050796=IDA, GO:0032800=IDA, GO:0016021=IEA, GO:0019722=IEA, GO:0045599=NAS, GO:0032715=IDA, GO:0002020=IPI, GO:0050901=IDA, GO:0042802=IDA, GO:0030730=IDA, GO:0043525=IEA, GO:0030198=IEA, GO:0061048=IDA, GO:0034116=IDA, GO:0009887=IEA, GO:0070374=NAS, GO:0043123=IDA, GO:0043122=IDA, GO:0032729=IEA, GO:0005164=IDA, GO:0002876=IEA, GO:0045416=IDA, GO:0051384=IDA, GO:0000122=IEA, GO:0032722=IDA, GO:0043242=IDA, GO:0033209=IMP, GO:0051798=IEA, GO:0050806=IEA, GO:0045123=IEA, GO:0045121=IDA, GO:0045893=IDA, GO:0045892=IDA, GO:0009897=ISS, GO:0008625=IDA, GO:0071803=IDA, GO:0042346=IDA, GO:0051897=IEA, GO:0060559=IDA, GO:0002439=IMP, GO:0051044=IDA, GO:0008285=IEA, GO:0060693=IEA, GO:0005886=TAS, GO:0060555=IDA, GO:0060557=IDA, GO:0006927=IDA, GO:0045429=IDA, GO:0002740=IDA, GO:0002925=IEA, GO:0002037=IEA, GO:0031334=IDA, GO:0071230=IEA, GO:0043406=IDA, GO:0043243=IDA, GO:0045944=IGI, GO:0043507=IDA, GO:0001666=IEA, GO:0014823=IEA, GO:0043066=IDA, GO:0043065=NAS, GO:0006919=IDA, GO:0030316=IEA, GO:0007254=IEA, GO:0006915=TAS, GO:0006917=IDA, GO:0097190=IDA, GO:0003009=IEA, GO:0001934=IDA, GO:0001932=IEA, GO:0055037=ISS} JNK cascade, activation of MAPK activity, activation of MAPKKK activity, activation of cysteine-type endopeptidase activity involved in apoptotic process, activation of necroptosis by extracellular signals, apoptotic process, apoptotic signaling pathway, calcium-mediated signaling, cell activation, cellular extravasation, cellular response to amino acid stimulus, cellular response to nicotine, chronic inflammatory response to antigenic stimulus, defense response to Gram-positive bacterium, embryonic digestive tract development, epithelial cell proliferation involved in salivary gland morphogenesis, extracellular matrix organization, extrinsic apoptotic signaling pathway via death domain receptors, glucose metabolic process, humoral immune response, induction of apoptosis, inflammatory response, leukocyte tethering or rolling, necrotic cell death, negative regulation of L-glutamate transport, negative regulation of alkaline phosphatase activity, negative regulation of apoptotic process, negative regulation of branching involved in lung morphogenesis, negative regulation of cell proliferation, negative regulation of cytokine secretion involved in immune response, negative regulation of fat cell differentiation, negative regulation of glucose import, negative regulation of growth of symbiont in host, negative regulation of interleukin-6 production, negative regulation of lipid catabolic process, negative regulation of lipid storage, negative regulation of osteoblast differentiation, negative regulation of protein complex disassembly, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, negative regulation of viral genome replication, organ morphogenesis, osteoclast differentiation, positive regulation of ERK1 and ERK2 cascade, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of JNK cascade, positive regulation of JUN kinase activity, positive regulation of MAP kinase activity, positive regulation of NF-kappaB import into nucleus, positive regulation of NF-kappaB transcription factor activity, positive regulation of NFAT protein import into nucleus, positive regulation of apoptotic process, positive regulation of calcidiol 1-monooxygenase activity, positive regulation of chemokine (C-X-C motif) ligand 2 production, positive regulation of chemokine biosynthetic process, positive regulation of chemokine production, positive regulation of chronic inflammatory response to antigenic stimulus, positive regulation of cytokine production, positive regulation of cytokine secretion, positive regulation of fever generation, positive regulation of hair follicle development, positive regulation of heterotypic cell-cell adhesion, positive regulation of humoral immune response mediated by circulating immunoglobulin, positive regulation of interferon-gamma production, positive regulation of interleukin-6 production, positive regulation of interleukin-8 biosynthetic process, positive regulation of membrane protein ectodomain proteolysis, positive regulation of mitosis, positive regulation of mononuclear cell migration, positive regulation of necrotic cell death, positive regulation of neuron apoptotic process, positive regulation of nitric oxide biosynthetic process, positive regulation of osteoclast differentiation, positive regulation of peptidyl-serine phosphorylation, positive regulation of podosome assembly, positive regulation of protein complex assembly, positive regulation of protein complex disassembly, positive regulation of protein kinase B signaling cascade, positive regulation of protein phosphorylation, positive regulation of protein transport, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of smooth muscle cell proliferation, positive regulation of synaptic transmission, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of translational initiation by iron, positive regulation of vitamin D biosynthetic process, protein import into nucleus, translocation, receptor biosynthetic process, regulation of I-kappaB kinase/NF-kappaB cascade, regulation of branching involved in salivary gland morphogenesis, regulation of immunoglobulin secretion, regulation of insulin secretion, regulation of osteoclast differentiation, regulation of protein phosphorylation, response to activity, response to drug, response to glucocorticoid stimulus, response to hypoxia, response to mechanical stimulus, response to salt stress, response to virus, sequestering of triglyceride, skeletal muscle contraction, transformed cell apoptotic process, tumor necrosis factor-mediated signaling pathway cell surface, external side of plasma membrane, extracellular space, integral to membrane, integral to plasma membrane, membrane raft, phagocytic cup, plasma membrane, recycling endosome cytokine activity, identical protein binding, protease binding, protein binding, transcription regulatory region DNA binding, tumor necrosis factor receptor binding Human TNFAIP1 HPA UniProtKB {GO:0004842=PMID:19782033, GO:0016567=PMID:19782033, GO:0035024=PMID:19782033, GO:0043149=PMID:19782033, GO:0019904=GO_REF:0000019, GO:0045740=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0006915=PMID:19637314, GO:0005634=GO_REF:0000052, GO:0009790=GO_REF:0000024, GO:0006260=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0006955=PMID:1370465, GO:0016477=PMID:19782033, GO:0031463=PMID:19782033, GO:0051260=GO_REF:0000002, GO:0043161=PMID:19782033, GO:0017049=PMID:19637314, GO:0005768=PMID:19637314} Q13829 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 protein 20090616 {GO:0004842=IDA, GO:0016567=IDA, GO:0035024=IMP, GO:0043149=IMP, GO:0019904=IEA, GO:0045740=IEA, GO:0005730=IDA, GO:0006915=TAS, GO:0005634=IDA, GO:0009790=ISS, GO:0006260=ISS, GO:0005737=IDA, GO:0006955=IEP, GO:0016477=IMP, GO:0031463=IDA, GO:0051260=IEA, GO:0043161=IDA, GO:0017049=IDA, GO:0005768=IDA} DNA replication, apoptotic process, cell migration, embryo development, immune response, negative regulation of Rho protein signal transduction, positive regulation of DNA replication, proteasomal ubiquitin-dependent protein catabolic process, protein homooligomerization, protein ubiquitination, stress fiber assembly Cul3-RING ubiquitin ligase complex, cytoplasm, endosome, nucleolus, nucleus GTP-Rho binding, protein domain specific binding, ubiquitin-protein ligase activity Human TNFAIP2 PINC UniProtKB {GO:0000145=GO_REF:0000002, GO:0001525=GO_REF:0000037, GO:0006887=GO_REF:0000002, GO:0005615=PMID:1374453, GO:0030154=GO_REF:0000037} Q03169 Tumor necrosis factor alpha-induced protein 2 protein 20030904 {GO:0000145=IEA, GO:0001525=IEA, GO:0006887=IEA, GO:0005615=TAS, GO:0030154=IEA} angiogenesis, cell differentiation, exocytosis exocyst, extracellular space Human TNFAIP3 ENSEMBL UniProtKB {GO:0005515=PMID:20392859, GO:0043130=PMID:19285159, GO:0016579=GO_REF:0000019, GO:0004842=PMID:15258597, GO:0004843=PMID:20392859, GO:0032715=GO_REF:0000019, GO:0032691=GO_REF:0000019, GO:0043621=PMID:8797804, GO:0002020=PMID:18223652, GO:0051259=PMID:15474016, GO:0005764=GO_REF:0000039, GO:0061043=PMID:16816117, GO:0070536=PMID:15258597, GO:0060548=GO_REF:0000019, GO:0006508=GO_REF:0000037, GO:0031397=PMID:20392859, GO:0043027=PMID:12167698, GO:0043124=PMID:21127049, GO:0005813=GO_REF:0000052, GO:0070433=GO_REF:0000019, GO:0072573=PMID:21220427, GO:0032720=GO_REF:0000019, GO:0090291=PMID:21127049, GO:0045087=Reactome:REACT_6802, GO:0008270=GO_REF:0000002, GO:0004221=PMID:15258597, GO:0034144=PMID:15142865, GO:0045732=PMID:21127049, GO:0034140=PMID:15474016, GO:0045736=GO_REF:0000019, GO:0002237=GO_REF:0000019, GO:0070423=Reactome:REACT_75776, GO:0005634=PMID:11463333, GO:0035872=Reactome:REACT_75913, GO:0045779=PMID:21127049, GO:0005829=Reactome:REACT_75888, GO:0005737=GO_REF:0000019, GO:0006954=GO_REF:0000037, GO:0070429=GO_REF:0000019, GO:0002677=GO_REF:0000019, GO:0001922=GO_REF:0000019, GO:0019900=GO_REF:0000019, GO:0043154=PMID:12167698, GO:0032480=Reactome:REACT_25271, GO:0002634=GO_REF:0000019, GO:0034136=PMID:15142865, GO:0032703=PMID:18223652, GO:0043066=PMID:12167698, GO:2000349=PMID:12885753, GO:0050869=GO_REF:0000019, GO:0032088=PMID:18223652, GO:0048662=PMID:16816117, GO:2000347=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0050691=PMID:15142865, GO:0071222=PMID:19912257, GO:0050728=GO_REF:0000024, GO:0032495=GO_REF:0000019, GO:0070936=PMID:15258597, GO:2000352=PMID:12885753, GO:0034148=GO_REF:0000019} Q5VXR0 A20p50 protein 20130413 {GO:0005515=IPI, GO:0043130=IPI, GO:0016579=IEA, GO:0004842=IDA, GO:0004843=TAS, GO:0032715=IEA, GO:0032691=IEA, GO:0043621=IDA, GO:0002020=IPI, GO:0051259=NAS, GO:0005764=IEA, GO:0061043=NAS, GO:0070536=IDA, GO:0060548=IEA, GO:0006508=IEA, GO:0031397=IDA, GO:0043027=NAS, GO:0043124=IDA, GO:0005813=IDA, GO:0070433=IEA, GO:0072573=IMP, GO:0032720=IEA, GO:0090291=NAS, GO:0045087=TAS, GO:0008270=IEA, GO:0004221=IMP, GO:0034144=NAS, GO:0045732=IDA, GO:0034140=IDA, GO:0045736=IEA, GO:0002237=IEA, GO:0070423=TAS, GO:0005634=IDA, GO:0035872=TAS, GO:0045779=NAS, GO:0005829=TAS, GO:0005737=IEA, GO:0006954=IEA, GO:0070429=IEA, GO:0002677=IEA, GO:0001922=IEA, GO:0019900=IEA, GO:0043154=IDA, GO:0032480=TAS, GO:0002634=IEA, GO:0034136=NAS, GO:0032703=IMP, GO:0043066=IDA, GO:2000349=IMP, GO:0050869=IEA, GO:0032088=IDA, GO:0048662=IDA, GO:2000347=IEA, GO:0003677=IEA, GO:0050691=NAS, GO:0071222=IDA, GO:0050728=ISS, GO:0032495=IEA, GO:0070936=IDA, GO:2000352=IDA, GO:0034148=IEA} B-1 B cell homeostasis, cellular response to lipopolysaccharide, inflammatory response, innate immune response, negative regulation of B cell activation, negative regulation of CD40 signaling pathway, negative regulation of I-kappaB kinase/NF-kappaB cascade, negative regulation of NF-kappaB transcription factor activity, negative regulation of apoptotic process, negative regulation of bone resorption, negative regulation of cell death, negative regulation of chronic inflammatory response, negative regulation of cyclin-dependent protein serine/threonine kinase activity, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of endothelial cell apoptotic process, negative regulation of inflammatory response, negative regulation of interleukin-1 beta production, negative regulation of interleukin-2 production, negative regulation of interleukin-6 production, negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway, negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway, negative regulation of osteoclast proliferation, negative regulation of protein ubiquitination, negative regulation of smooth muscle cell proliferation, negative regulation of toll-like receptor 2 signaling pathway, negative regulation of toll-like receptor 3 signaling pathway, negative regulation of toll-like receptor 4 signaling pathway, negative regulation of toll-like receptor 5 signaling pathway, negative regulation of tumor necrosis factor production, negative regulation of type I interferon production, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, nucleotide-binding oligomerization domain containing signaling pathway, positive regulation of hepatocyte proliferation, positive regulation of protein catabolic process, protein K48-linked ubiquitination, protein K63-linked deubiquitination, protein deubiquitination, protein oligomerization, proteolysis, regulation of defense response to virus by host, regulation of germinal center formation, regulation of vascular wound healing, response to molecule of bacterial origin, response to muramyl dipeptide, tolerance induction to lipopolysaccharide centrosome, cytoplasm, cytosol, lysosome, nucleus DNA binding, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, kinase binding, protease binding, protein binding, protein self-association, ubiquitin binding, ubiquitin thiolesterase activity, ubiquitin-protein ligase activity, ubiquitin-specific protease activity, zinc ion binding Human Ensembl:ENSMUSP00000019997 TNFAIP6 PINC UniProtKB {GO:0007165=PMID:1730767, GO:0006954=PMID:1730767, GO:0005540=GO_REF:0000002, GO:0007267=PMID:1730767, GO:0007155=GO_REF:0000037} P98066 Tumor necrosis factor-inducible gene 6 protein protein 20030904 {GO:0007165=TAS, GO:0006954=TAS, GO:0005540=IEA, GO:0007267=TAS, GO:0007155=IEA} cell adhesion, cell-cell signaling, inflammatory response, signal transduction hyaluronic acid binding Human TNFAIP8 GOC UniProtKB {GO:0043066=PMID:10644768, GO:0005737=PMID:14724590, GO:0043154=PMID:10644768, GO:0043027=PMID:10644768} O95379 Tumor necrosis factor alpha-induced protein 8 protein 20130413 {GO:0043066=TAS, GO:0005737=IDA, GO:0043154=IMP, GO:0043027=IMP} negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process cytoplasm cysteine-type endopeptidase inhibitor activity involved in apoptotic process Human TNFAIP8L1 null null {} null null null null {} null null null TNFRSF10A IntAct UniProtKB {GO:0008625=PMID:9311998, GO:0005515=PMID:20103630, GO:0045569=PMID:9373179, GO:0007250=PMID:11464292, GO:0006919=GO_REF:0000029, GO:0006917=PMID:9311998, GO:0097191=PMID:21785459, GO:0007165=PMID:9082980, GO:0004872=PMID:9311998, GO:0016021=PMID:9311998, GO:0071260=PMID:19593445, GO:0008134=PMID:18165900, GO:0005035=PMID:9082980} O00220 Tumor necrosis factor receptor superfamily member 10A protein 20130415 {GO:0008625=NAS, GO:0005515=IPI, GO:0045569=NAS, GO:0007250=NAS, GO:0006919=NAS, GO:0006917=NAS, GO:0097191=IDA, GO:0007165=TAS, GO:0004872=NAS, GO:0016021=IC, GO:0071260=IEP, GO:0008134=IPI, GO:0005035=TAS} activation of NF-kappaB-inducing kinase activity, activation of cysteine-type endopeptidase activity involved in apoptotic process, cellular response to mechanical stimulus, extrinsic apoptotic signaling pathway, extrinsic apoptotic signaling pathway via death domain receptors, induction of apoptosis, signal transduction integral to membrane TRAIL binding, death receptor activity, protein binding, receptor activity, transcription factor binding Human UniProtKB:P50591 TNFRSF10B IntAct UniProtKB {GO:0005515=PMID:22266862, GO:0008625=PMID:9311998, GO:0034976=PMID:15322075, GO:0005886=Reactome:REACT_2170, GO:0007250=PMID:9430227, GO:0045569=PMID:9373179, GO:0006919=Reactome:REACT_1503, GO:0006915=Reactome:REACT_578, GO:0042981=PMID:10549288, GO:0097190=Reactome:REACT_1619, GO:0007165=GO_REF:0000002, GO:0070059=PMID:15322075, GO:0004872=PMID:9311998, GO:0016021=PMID:9311998, GO:0043123=PMID:12761501, GO:0071260=PMID:19593445, GO:0007166=PMID:9311998} O14763 Tumor necrosis factor receptor superfamily member 10B protein 20130415 {GO:0005515=IPI, GO:0008625=NAS, GO:0034976=IDA, GO:0005886=TAS, GO:0007250=NAS, GO:0045569=NAS, GO:0006919=TAS, GO:0006915=TAS, GO:0042981=NAS, GO:0097190=TAS, GO:0007165=IEA, GO:0070059=IMP, GO:0004872=NAS, GO:0016021=IC, GO:0043123=IEP, GO:0071260=IEP, GO:0007166=TAS} activation of NF-kappaB-inducing kinase activity, activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, apoptotic signaling pathway, cell surface receptor signaling pathway, cellular response to mechanical stimulus, extrinsic apoptotic signaling pathway via death domain receptors, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, positive regulation of I-kappaB kinase/NF-kappaB cascade, regulation of apoptotic process, response to endoplasmic reticulum stress, signal transduction integral to membrane, plasma membrane TRAIL binding, protein binding, receptor activity Human UniProtKB:P50591 TNFRSF10C PINC UniProtKB {GO:0007165=PMID:9314565, GO:0045569=GO_REF:0000002, GO:0005887=PMID:9314565, GO:0006915=GO_REF:0000037, GO:0031225=GO_REF:0000037, GO:0004888=PMID:9314565} O14798 Tumor necrosis factor receptor superfamily member 10C protein 20030904 {GO:0007165=TAS, GO:0045569=IEA, GO:0005887=TAS, GO:0006915=IEA, GO:0031225=IEA, GO:0004888=TAS} apoptotic process, signal transduction anchored to membrane, integral to plasma membrane TRAIL binding, transmembrane signaling receptor activity Human TNFRSF10D PINC UniProtKB {GO:0007165=PMID:9430226, GO:0043066=PMID:9430226, GO:0045569=GO_REF:0000002, GO:0006915=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0004888=PMID:9430226} Q9UBN6 Tumor necrosis factor receptor superfamily member 10D protein 20050308 {GO:0007165=TAS, GO:0043066=TAS, GO:0045569=IEA, GO:0006915=IEA, GO:0016021=IEA, GO:0004888=TAS} apoptotic process, negative regulation of apoptotic process, signal transduction integral to membrane TRAIL binding, transmembrane signaling receptor activity Human TNFRSF11A BHF-UCL UniProtKB {GO:0005515=PMID:15750601, GO:0008284=PMID:9367155, GO:0071848=PMID:18606301, GO:0007267=PMID:9367155, GO:0060086=PMID:19940926, GO:0046872=GO_REF:0000037, GO:0051091=PMID:12296995, GO:0051092=PMID:12296995, GO:0032496=PMID:19940926, GO:0004872=PMID:9367155, GO:0071847=PMID:18606301, GO:0043507=PMID:12296995, GO:0043123=PMID:19641626, GO:0034097=PMID:18606301, GO:0070555=PMID:19940926, GO:0071812=PMID:19940926, GO:0030316=PMID:18606301, GO:0033209=PMID:19940926, GO:0002548=PMID:15248232, GO:0002250=PMID:18606301, GO:0007165=PMID:9367155, GO:0005031=PMID:19940926, GO:0019955=PMID:9367155, GO:0034612=PMID:19940926, GO:0016021=GO_REF:0000037, GO:0009897=PMID:9367155, GO:0004888=PMID:9367155} Q9Y6Q6 Tumor necrosis factor receptor superfamily member 11A protein 20100611 {GO:0005515=IPI, GO:0008284=TAS, GO:0071848=IMP, GO:0007267=TAS, GO:0060086=ISS, GO:0046872=IEA, GO:0051091=IDA, GO:0051092=IMP, GO:0032496=ISS, GO:0004872=TAS, GO:0071847=IMP, GO:0043507=IMP, GO:0043123=RCA, GO:0034097=IMP, GO:0070555=ISS, GO:0071812=ISS, GO:0030316=IMP, GO:0033209=ISS, GO:0002548=NAS, GO:0002250=IMP, GO:0007165=TAS, GO:0005031=ISS, GO:0019955=IPI, GO:0034612=ISS, GO:0016021=IEA, GO:0009897=IDA, GO:0004888=IDA} TNFSF11-mediated signaling pathway, adaptive immune response, cell-cell signaling, circadian temperature homeostasis, monocyte chemotaxis, osteoclast differentiation, positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of JUN kinase activity, positive regulation of NF-kappaB transcription factor activity, positive regulation of cell proliferation, positive regulation of fever generation by positive regulation of prostaglandin secretion, positive regulation of sequence-specific DNA binding transcription factor activity, response to cytokine stimulus, response to interleukin-1, response to lipopolysaccharide, response to tumor necrosis factor, signal transduction, tumor necrosis factor-mediated signaling pathway external side of plasma membrane, integral to membrane cytokine binding, metal ion binding, protein binding, receptor activity, transmembrane signaling receptor activity, tumor necrosis factor-activated receptor activity Human UniProtKB:O35305 TNFRSF11B BHF-UCL UniProtKB {GO:0043627=GO_REF:0000019, GO:0046685=GO_REF:0000019, GO:0007584=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0005578=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0005576=PMID:9108485, GO:0005615=PMID:15516325, GO:0005125=PMID:9168977, GO:0045779=GO_REF:0000019, GO:0007165=GO_REF:0000002, GO:0001501=PMID:9108485, GO:0030198=GO_REF:0000019, GO:0032026=GO_REF:0000019, GO:0004872=PMID:9108485, GO:0042489=GO_REF:0000019} O00300 Tumor necrosis factor receptor superfamily member 11B protein 20120501 {GO:0043627=IEA, GO:0046685=IEA, GO:0007584=IEA, GO:0042493=IEA, GO:0005578=IEA, GO:0006915=IEA, GO:0005576=TAS, GO:0005615=IDA, GO:0005125=TAS, GO:0045779=IEA, GO:0007165=IEA, GO:0001501=TAS, GO:0030198=IEA, GO:0032026=IEA, GO:0004872=TAS, GO:0042489=IEA} apoptotic process, extracellular matrix organization, negative regulation of bone resorption, negative regulation of odontogenesis of dentin-containing tooth, response to arsenic-containing substance, response to drug, response to estrogen stimulus, response to magnesium ion, response to nutrient, signal transduction, skeletal system development extracellular region, extracellular space, proteinaceous extracellular matrix cytokine activity, receptor activity Human TNFRSF12A IntAct UniProtKB {GO:0005515=PMID:21525013, GO:0008219=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0045773=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0006928=PMID:10551889, GO:0007275=PMID:10551889, GO:0001525=GO_REF:0000037, GO:0006917=PMID:21525013, GO:0001726=GO_REF:0000019, GO:0006931=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q9NP84 Tumor necrosis factor receptor superfamily member 12A protein 20130415 {GO:0005515=IPI, GO:0008219=IEA, GO:0005886=IEA, GO:0009986=IEA, GO:0045773=IEA, GO:0006915=IEA, GO:0006928=TAS, GO:0007275=TAS, GO:0001525=IEA, GO:0006917=IDA, GO:0001726=IEA, GO:0006931=IEA, GO:0016021=IEA} angiogenesis, apoptotic process, cell death, cellular component movement, induction of apoptosis, multicellular organismal development, positive regulation of axon extension, substrate-dependent cell migration, cell attachment to substrate cell surface, integral to membrane, plasma membrane, ruffle protein binding Human UniProtKB:Q13490 TNFRSF13B PINC UniProtKB {GO:0001782=GO_REF:0000019, GO:0005887=GO_REF:0000019, GO:0030889=GO_REF:0000019, GO:0004872=PMID:9311921, GO:0007166=PMID:9311921, GO:0009897=GO_REF:0000019} O14836 Tumor necrosis factor receptor superfamily member 13B protein 20030904 {GO:0001782=IEA, GO:0005887=IEA, GO:0030889=IEA, GO:0004872=TAS, GO:0007166=TAS, GO:0009897=IEA} B cell homeostasis, cell surface receptor signaling pathway, negative regulation of B cell proliferation external side of plasma membrane, integral to plasma membrane receptor activity Human TNFRSF13C ENSEMBL UniProtKB {GO:0001782=GO_REF:0000019, GO:0030890=GO_REF:0000019, GO:0045078=GO_REF:0000019, GO:0031296=GO_REF:0000019, GO:0042102=GO_REF:0000019, GO:0031295=GO_REF:0000019, GO:0002636=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0009897=GO_REF:0000019} Q96RJ3 Tumor necrosis factor receptor superfamily member 13C protein 20130413 {GO:0001782=IEA, GO:0030890=IEA, GO:0045078=IEA, GO:0031296=IEA, GO:0042102=IEA, GO:0031295=IEA, GO:0002636=IEA, GO:0016021=IEA, GO:0009897=IEA} B cell costimulation, B cell homeostasis, T cell costimulation, positive regulation of B cell proliferation, positive regulation of T cell proliferation, positive regulation of germinal center formation, positive regulation of interferon-gamma biosynthetic process external side of plasma membrane, integral to membrane Human Ensembl:ENSMUSP00000086564 TNFRSF14 GOC UniProtKB {GO:0005515=PMID:10318773, GO:0005886=Reactome:REACT_19406, GO:0046642=GO_REF:0000019, GO:0031295=Reactome:REACT_19344, GO:0050731=GO_REF:0000019, GO:0033209=PMID:9153189, GO:0006955=PMID:9162022, GO:0005031=PMID:9153189, GO:0005887=PMID:9153189, GO:0019048=GO_REF:0000037, GO:0009897=GO_REF:0000019, GO:0031625=PMID:11279055, GO:0007166=PMID:9153189} Q92956 Tumor necrosis factor receptor superfamily member 14 protein 20130413 {GO:0005515=IPI, GO:0005886=TAS, GO:0046642=IEA, GO:0031295=TAS, GO:0050731=IEA, GO:0033209=TAS, GO:0006955=TAS, GO:0005031=TAS, GO:0005887=IC, GO:0019048=IEA, GO:0009897=IEA, GO:0031625=IPI, GO:0007166=TAS} T cell costimulation, cell surface receptor signaling pathway, immune response, negative regulation of alpha-beta T cell proliferation, positive regulation of peptidyl-tyrosine phosphorylation, tumor necrosis factor-mediated signaling pathway, virus-host interaction external side of plasma membrane, integral to plasma membrane, plasma membrane protein binding, tumor necrosis factor-activated receptor activity, ubiquitin protein ligase binding Human TNFRSF17 GOC UniProtKB {GO:0007165=PMID:10908663, GO:0005031=PMID:19641626, GO:0005886=GO_REF:0000039, GO:0008283=PMID:10908663, GO:0007275=PMID:8165126, GO:0004872=PMID:10908663, GO:0016021=GO_REF:0000037, GO:0033209=PMID:19641626, GO:0012505=GO_REF:0000039} Q02223 Tumor necrosis factor receptor superfamily member 17 protein 20130413 {GO:0007165=TAS, GO:0005031=RCA, GO:0005886=IEA, GO:0008283=TAS, GO:0007275=TAS, GO:0004872=TAS, GO:0016021=IEA, GO:0033209=RCA, GO:0012505=IEA} cell proliferation, multicellular organismal development, signal transduction, tumor necrosis factor-mediated signaling pathway endomembrane system, integral to membrane, plasma membrane receptor activity, tumor necrosis factor-activated receptor activity Human TNFRSF18 GOC UniProtKB {GO:0007165=PMID:10074428, GO:0043066=PMID:10074428, GO:0005031=PMID:10074428, GO:0005887=GO_REF:0000002, GO:0006915=GO_REF:0000037, GO:0005576=GO_REF:0000039, GO:0033209=PMID:10074428, GO:0009897=GO_REF:0000019} Q9Y5U5 Tumor necrosis factor receptor superfamily member 18 protein 20130413 {GO:0007165=TAS, GO:0043066=TAS, GO:0005031=TAS, GO:0005887=IEA, GO:0006915=IEA, GO:0005576=IEA, GO:0033209=TAS, GO:0009897=IEA} apoptotic process, negative regulation of apoptotic process, signal transduction, tumor necrosis factor-mediated signaling pathway external side of plasma membrane, extracellular region, integral to plasma membrane tumor necrosis factor-activated receptor activity Human TNFRSF19 GOC UniProtKB {GO:0005031=PMID:10809768, GO:0007254=PMID:10809768, GO:0006915=GO_REF:0000037, GO:0006917=PMID:10809768, GO:0016021=PMID:10809768, GO:0043123=PMID:19641626, GO:0001942=GO_REF:0000019, GO:0033209=PMID:10809768} Q9NS68 Tumor necrosis factor receptor superfamily member 19 protein 20130413 {GO:0005031=NAS, GO:0007254=NAS, GO:0006915=IEA, GO:0006917=NAS, GO:0016021=NAS, GO:0043123=RCA, GO:0001942=IEA, GO:0033209=NAS} JNK cascade, apoptotic process, hair follicle development, induction of apoptosis, positive regulation of I-kappaB kinase/NF-kappaB cascade, tumor necrosis factor-mediated signaling pathway integral to membrane tumor necrosis factor-activated receptor activity Human TNFRSF1A BHF-UCL UniProtKB {GO:0005515=PMID:22817896, GO:0030424=GO_REF:0000019, GO:0006693=GO_REF:0000002, GO:0033160=GO_REF:0000019, GO:0005886=Reactome:REACT_2175, GO:0032715=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0019221=GO_REF:0000024, GO:0005634=GO_REF:0000019, GO:0002020=GO_REF:0000019, GO:0051291=GO_REF:0000019, GO:0005615=PMID:13130484, GO:0032403=GO_REF:0000019, GO:0006954=GO_REF:0000024, GO:0071392=GO_REF:0000019, GO:0045944=PMID:21410936, GO:0032496=GO_REF:0000019, GO:0043123=PMID:12761501, GO:0043200=GO_REF:0000019, GO:0042742=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0032760=GO_REF:0000019, GO:0043120=GO_REF:0000019, GO:0042511=PMID:21410936, GO:0006915=Reactome:REACT_578, GO:0005576=PMID:12189246, GO:0042981=GO_REF:0000019, GO:0043279=GO_REF:0000019, GO:0097190=Reactome:REACT_1619, GO:0033013=GO_REF:0000019, GO:0045766=GO_REF:0000019, GO:0007165=GO_REF:0000002, GO:0043234=GO_REF:0000019, GO:0005031=PMID:2158863, GO:0000139=PMID:22801493, GO:0009812=GO_REF:0000019, GO:0005887=PMID:1698610, GO:0050728=PMID:13130484, GO:0019048=GO_REF:0000037, GO:0050729=GO_REF:0000024, GO:0010629=GO_REF:0000019, GO:0016101=GO_REF:0000019, GO:0045121=PMID:17010968, GO:0071260=PMID:19593445} P19438 Tumor necrosis factor receptor superfamily member 1A protein 20120622 {GO:0005515=IPI, GO:0030424=IEA, GO:0006693=IEA, GO:0033160=IEA, GO:0005886=TAS, GO:0032715=IEA, GO:0045471=IEA, GO:0019221=ISS, GO:0005634=IEA, GO:0002020=IEA, GO:0051291=IEA, GO:0005615=IDA, GO:0032403=IEA, GO:0006954=ISS, GO:0071392=IEA, GO:0045944=IMP, GO:0032496=IEA, GO:0043123=IEP, GO:0043200=IEA, GO:0042742=IEA, GO:0001666=IEA, GO:0009986=IEA, GO:0032760=IEA, GO:0043120=IEA, GO:0042511=IMP, GO:0006915=TAS, GO:0005576=NAS, GO:0042981=IEA, GO:0043279=IEA, GO:0097190=TAS, GO:0033013=IEA, GO:0045766=IEA, GO:0007165=IEA, GO:0043234=IEA, GO:0005031=TAS, GO:0000139=IDA, GO:0009812=IEA, GO:0005887=TAS, GO:0050728=IMP, GO:0019048=IEA, GO:0050729=ISS, GO:0010629=IEA, GO:0016101=IEA, GO:0045121=IDA, GO:0071260=IEP} apoptotic process, apoptotic signaling pathway, cellular response to estradiol stimulus, cellular response to mechanical stimulus, cytokine-mediated signaling pathway, defense response to bacterium, diterpenoid metabolic process, flavonoid metabolic process, inflammatory response, negative regulation of gene expression, negative regulation of inflammatory response, negative regulation of interleukin-6 production, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of angiogenesis, positive regulation of inflammatory response, positive regulation of protein import into nucleus, translocation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of tumor necrosis factor production, positive regulation of tyrosine phosphorylation of Stat1 protein, prostaglandin metabolic process, protein heterooligomerization, regulation of apoptotic process, response to alkaloid, response to amino acid stimulus, response to ethanol, response to hypoxia, response to lipopolysaccharide, signal transduction, tetrapyrrole metabolic process, virus-host interaction Golgi membrane, axon, cell surface, extracellular region, extracellular space, integral to plasma membrane, membrane raft, nucleus, plasma membrane, protein complex protease binding, protein binding, protein complex binding, tumor necrosis factor binding, tumor necrosis factor-activated receptor activity Human TNFRSF1B BHF-UCL UniProtKB {GO:0005515=PMID:10848577, GO:0051044=PMID:22480688, GO:0048471=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0006955=GO_REF:0000019, GO:0050779=GO_REF:0000019, GO:0071222=PMID:22480688, GO:0005031=GO_REF:0000019, GO:0006954=GO_REF:0000019, GO:0071363=GO_REF:0000019, GO:0050728=GO_REF:0000019, GO:0043196=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0045121=PMID:17010968, GO:0016021=GO_REF:0000037, GO:0031625=PMID:11279055} P20333 Tumor necrosis factor receptor superfamily member 1B protein 20120704 {GO:0005515=IPI, GO:0051044=IMP, GO:0048471=IEA, GO:0005886=IEA, GO:0006915=IEA, GO:0005634=IEA, GO:0005576=IEA, GO:0006955=IEA, GO:0050779=IEA, GO:0071222=IMP, GO:0005031=IEA, GO:0006954=IEA, GO:0071363=IEA, GO:0050728=IEA, GO:0043196=IEA, GO:0043025=IEA, GO:0045121=IDA, GO:0016021=IEA, GO:0031625=IPI} RNA destabilization, apoptotic process, cellular response to growth factor stimulus, cellular response to lipopolysaccharide, immune response, inflammatory response, negative regulation of inflammatory response, positive regulation of membrane protein ectodomain proteolysis extracellular region, integral to membrane, membrane raft, neuronal cell body, nucleus, perinuclear region of cytoplasm, plasma membrane, varicosity protein binding, tumor necrosis factor-activated receptor activity, ubiquitin protein ligase binding Human TNFRSF21 HPA UniProtKB {GO:0005515=PMID:19225519, GO:0030424=GO_REF:0000019, GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0005886=Reactome:REACT_115875, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0051402=GO_REF:0000019, GO:0044255=Reactome:REACT_22279} O75509 Tumor necrosis factor receptor superfamily member 21 protein 20080205 {GO:0005515=IPI, GO:0030424=IEA, GO:0007165=IEA, GO:0005737=IDA, GO:0005886=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0051402=IEA, GO:0044255=TAS} cellular lipid metabolic process, neuron apoptotic process, signal transduction, small molecule metabolic process axon, cytoplasm, integral to membrane, plasma membrane protein binding Human TNFRSF25 GOC UniProtKB {GO:0005886=PMID:11911831, GO:0006915=PMID:9114039, GO:0005576=GO_REF:0000039, GO:0042981=PMID:9114039, GO:0006917=PMID:8875942, GO:0097190=PMID:8994832, GO:0033209=PMID:9052839, GO:0005829=PMID:9114039, GO:0007165=PMID:8994832, GO:0005031=PMID:9052839, GO:0005887=PMID:9052839, GO:0004872=PMID:9114039, GO:0007166=PMID:9052839} Q93038 Tumor necrosis factor receptor superfamily member 25 protein 20130413 {GO:0005886=IDA, GO:0006915=NAS, GO:0005576=IEA, GO:0042981=NAS, GO:0006917=TAS, GO:0097190=TAS, GO:0033209=TAS, GO:0005829=NAS, GO:0007165=TAS, GO:0005031=TAS, GO:0005887=TAS, GO:0004872=NAS, GO:0007166=TAS} apoptotic process, apoptotic signaling pathway, cell surface receptor signaling pathway, induction of apoptosis, regulation of apoptotic process, signal transduction, tumor necrosis factor-mediated signaling pathway cytosol, extracellular region, integral to plasma membrane, plasma membrane receptor activity, tumor necrosis factor-activated receptor activity Human TNFRSF4 BHF-UCL UniProtKB {GO:0045859=GO_REF:0000019, GO:0009986=GO_REF:0000024, GO:0030890=GO_REF:0000024, GO:0042981=GO_REF:0000019, GO:0050710=GO_REF:0000019, GO:0043433=GO_REF:0000024, GO:0006968=GO_REF:0000019, GO:0006955=PMID:7510240, GO:0005031=GO_REF:0000019, GO:0006954=GO_REF:0000019, GO:0042098=GO_REF:0000024, GO:0005887=PMID:7510240, GO:0051024=GO_REF:0000024, GO:0045892=GO_REF:0000024, GO:0009897=GO_REF:0000019} P43489 Tumor necrosis factor receptor superfamily member 4 protein 20090430 {GO:0045859=IEA, GO:0009986=ISS, GO:0030890=ISS, GO:0042981=IEA, GO:0050710=IEA, GO:0043433=ISS, GO:0006968=IEA, GO:0006955=TAS, GO:0005031=IEA, GO:0006954=IEA, GO:0042098=ISS, GO:0005887=TAS, GO:0051024=ISS, GO:0045892=ISS, GO:0009897=IEA} T cell proliferation, cellular defense response, immune response, inflammatory response, negative regulation of cytokine secretion, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription, DNA-dependent, positive regulation of B cell proliferation, positive regulation of immunoglobulin secretion, regulation of apoptotic process, regulation of protein kinase activity cell surface, external side of plasma membrane, integral to plasma membrane tumor necrosis factor-activated receptor activity Human UniProtKB:P47741 TNFRSF6B IntAct UniProtKB {GO:0005515=PMID:10318773, GO:0043066=PMID:9872321, GO:0006915=GO_REF:0000037, GO:0004872=PMID:9872321, GO:0005615=PMID:10318773} O95407 Tumor necrosis factor receptor superfamily member 6B protein 20130415 {GO:0005515=IPI, GO:0043066=TAS, GO:0006915=IEA, GO:0004872=TAS, GO:0005615=NAS} apoptotic process, negative regulation of apoptotic process extracellular space protein binding, receptor activity Human UniProtKB:O43557 TNFRSF8 GOC UniProtKB {GO:0007165=PMID:10192335, GO:0005737=GO_REF:0000039, GO:0008285=PMID:10192335, GO:0005031=PMID:19641626, GO:0043065=PMID:16108830, GO:0005886=GO_REF:0000039, GO:0042535=PMID:16108830, GO:0016021=GO_REF:0000037, GO:0071260=PMID:19593445, GO:0033209=PMID:19641626, GO:0045556=PMID:16108830, GO:0004888=PMID:1310894} P28908 Tumor necrosis factor receptor superfamily member 8 protein 20130413 {GO:0007165=TAS, GO:0005737=IEA, GO:0008285=TAS, GO:0005031=RCA, GO:0043065=IDA, GO:0005886=IEA, GO:0042535=IDA, GO:0016021=IEA, GO:0071260=IEP, GO:0033209=RCA, GO:0045556=IDA, GO:0004888=TAS} cellular response to mechanical stimulus, negative regulation of cell proliferation, positive regulation of TRAIL biosynthetic process, positive regulation of apoptotic process, positive regulation of tumor necrosis factor biosynthetic process, signal transduction, tumor necrosis factor-mediated signaling pathway cytoplasm, integral to membrane, plasma membrane transmembrane signaling receptor activity, tumor necrosis factor-activated receptor activity Human TNFRSF9 PINC UniProtKB {GO:0008285=PMID:8639902, GO:0005887=PMID:8262389, GO:0004872=GO_REF:0000019, GO:0006917=PMID:8639902, GO:0009897=GO_REF:0000019} Q07011 Tumor necrosis factor receptor superfamily member 9 protein 20030904 {GO:0008285=TAS, GO:0005887=TAS, GO:0004872=IEA, GO:0006917=TAS, GO:0009897=IEA} induction of apoptosis, negative regulation of cell proliferation external side of plasma membrane, integral to plasma membrane receptor activity Human TNFSF10 IntAct UniProtKB {GO:0005515=PMID:22266862, GO:0005164=GO_REF:0000002, GO:2001238=PMID:21525171, GO:0006919=Reactome:REACT_1503, GO:0007267=PMID:8777713, GO:0005102=PMID:8777713, GO:0006915=Reactome:REACT_578, GO:0005576=Reactome:REACT_2170, GO:0006917=PMID:8663110, GO:0097190=Reactome:REACT_1619, GO:0005125=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0043280=PMID:21525171, GO:0007165=PMID:8777713, GO:0006955=GO_REF:0000002, GO:0005887=PMID:8663110, GO:0090200=PMID:22266862, GO:0043123=PMID:12761501} P50591 Tumor necrosis factor ligand superfamily member 10 protein 20130415 {GO:0005515=IPI, GO:0005164=IEA, GO:2001238=IDA, GO:0006919=TAS, GO:0007267=TAS, GO:0005102=TAS, GO:0006915=TAS, GO:0005576=TAS, GO:0006917=TAS, GO:0097190=TAS, GO:0005125=IEA, GO:0005615=IEA, GO:0046872=IEA, GO:0043280=IDA, GO:0007165=TAS, GO:0006955=IEA, GO:0005887=TAS, GO:0090200=IDA, GO:0043123=IEP} activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, apoptotic signaling pathway, cell-cell signaling, immune response, induction of apoptosis, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of extrinsic apoptotic signaling pathway, positive regulation of release of cytochrome c from mitochondria, signal transduction extracellular region, extracellular space, integral to plasma membrane cytokine activity, metal ion binding, protein binding, receptor binding, tumor necrosis factor receptor binding Human UniProtKB:O14763 TNFSF11 BHF-UCL UniProtKB {GO:0051897=GO_REF:0000019, GO:0071848=PMID:18606301, GO:0045453=GO_REF:0000019, GO:0019221=PMID:15248232, GO:0046330=GO_REF:0000019, GO:0032813=PMID:19940926, GO:0005615=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0006955=PMID:9312132, GO:0051091=PMID:19940926, GO:0051092=PMID:9367155, GO:0045780=PMID:17241109, GO:0043406=PMID:15304486, GO:0045944=PMID:15304486, GO:0009887=GO_REF:0000019, GO:0071847=PMID:18606301, GO:0051260=GO_REF:0000019, GO:0070371=GO_REF:0000019, GO:0043123=GO_REF:0000019, GO:0051466=PMID:19940926, GO:0010740=PMID:15248232, GO:0005164=PMID:9367155, GO:0071812=PMID:19940926, GO:0030316=PMID:18606301, GO:0045672=PMID:15304486, GO:0005576=PMID:10708588, GO:0034112=PMID:9367155, GO:0007257=GO_REF:0000019, GO:0005125=PMID:9367155, GO:0033209=PMID:19940926, GO:0002548=PMID:15248232, GO:0033598=GO_REF:0000019, GO:0001503=GO_REF:0000019, GO:0005887=PMID:9312132, GO:0050870=PMID:9367155, GO:0060749=GO_REF:0000019} O14788 Tumor necrosis factor ligand superfamily member 11 protein 20100611 {GO:0051897=IEA, GO:0071848=IDA, GO:0045453=IEA, GO:0019221=IDA, GO:0046330=IEA, GO:0032813=IC, GO:0005615=IEA, GO:0005737=IEA, GO:0006955=NAS, GO:0051091=ISS, GO:0051092=IDA, GO:0045780=IDA, GO:0043406=IDA, GO:0045944=IDA, GO:0009887=IEA, GO:0071847=IDA, GO:0051260=IEA, GO:0070371=IEA, GO:0043123=IEA, GO:0051466=ISS, GO:0010740=IDA, GO:0005164=NAS, GO:0071812=ISS, GO:0030316=IDA, GO:0045672=IDA, GO:0005576=NAS, GO:0034112=IDA, GO:0007257=IEA, GO:0005125=IDA, GO:0033209=ISS, GO:0002548=IDA, GO:0033598=IEA, GO:0001503=IEA, GO:0005887=NAS, GO:0050870=IDA, GO:0060749=IEA} ERK1 and ERK2 cascade, TNFSF11-mediated signaling pathway, activation of JUN kinase activity, bone resorption, cytokine-mediated signaling pathway, immune response, mammary gland alveolus development, mammary gland epithelial cell proliferation, monocyte chemotaxis, organ morphogenesis, ossification, osteoclast differentiation, positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of JNK cascade, positive regulation of MAP kinase activity, positive regulation of NF-kappaB transcription factor activity, positive regulation of T cell activation, positive regulation of bone resorption, positive regulation of corticotropin-releasing hormone secretion, positive regulation of fever generation by positive regulation of prostaglandin secretion, positive regulation of homotypic cell-cell adhesion, positive regulation of intracellular protein kinase cascade, positive regulation of osteoclast differentiation, positive regulation of protein kinase B signaling cascade, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, protein homooligomerization, tumor necrosis factor-mediated signaling pathway cytoplasm, extracellular region, extracellular space, integral to plasma membrane cytokine activity, tumor necrosis factor receptor binding, tumor necrosis factor receptor superfamily binding Human UniProtKB:O35235 TNFSF12 PINC UniProtKB {GO:0005515=PMID:14961121, GO:0005164=GO_REF:0000002, GO:0048471=PMID:14961121, GO:0005102=PMID:9560343, GO:0006915=GO_REF:0000037, GO:0006917=PMID:9560343, GO:0001525=GO_REF:0000037, GO:0005125=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0045766=PMID:14961121, GO:0007165=PMID:9560343, GO:0006955=GO_REF:0000002, GO:0001938=PMID:14961121, GO:0005887=PMID:9560343, GO:0043542=PMID:14961121} O43508 Tumor necrosis factor ligand superfamily member 12 protein 20030904 {GO:0005515=IPI, GO:0005164=IEA, GO:0048471=IDA, GO:0005102=TAS, GO:0006915=IEA, GO:0006917=TAS, GO:0001525=IEA, GO:0005125=IEA, GO:0005615=IEA, GO:0030154=IEA, GO:0045766=TAS, GO:0007165=TAS, GO:0006955=IEA, GO:0001938=TAS, GO:0005887=TAS, GO:0043542=TAS} angiogenesis, apoptotic process, cell differentiation, endothelial cell migration, immune response, induction of apoptosis, positive regulation of angiogenesis, positive regulation of endothelial cell proliferation, signal transduction extracellular space, integral to plasma membrane, perinuclear region of cytoplasm cytokine activity, protein binding, receptor binding, tumor necrosis factor receptor binding Human TNFSF13 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0005164=GO_REF:0000002, GO:0008284=GO_REF:0000019, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0002426=GO_REF:0000019, GO:0048298=PMID:14988498, GO:0005102=PMID:9743536, GO:0005125=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0005829=Reactome:REACT_24924, GO:0007165=PMID:9743536, GO:0006955=GO_REF:0000002, GO:0016020=GO_REF:0000002, GO:0002636=GO_REF:0000019, GO:0005654=Reactome:REACT_25286, GO:0009897=GO_REF:0000019} O75888 Tumor necrosis factor ligand superfamily member 13 protein 20091216 {GO:0010467=TAS, GO:0005164=IEA, GO:0008284=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0002426=IEA, GO:0048298=IDA, GO:0005102=TAS, GO:0005125=IEA, GO:0005615=IEA, GO:0005829=TAS, GO:0007165=TAS, GO:0006955=IEA, GO:0016020=IEA, GO:0002636=IEA, GO:0005654=TAS, GO:0009897=IEA} RNA metabolic process, gene expression, immune response, immunoglobulin production in mucosal tissue, mRNA metabolic process, positive regulation of cell proliferation, positive regulation of germinal center formation, positive regulation of isotype switching to IgA isotypes, signal transduction cytosol, external side of plasma membrane, extracellular space, membrane, nucleoplasm cytokine activity, receptor binding, tumor necrosis factor receptor binding Human TNFSF13B PINC UniProtKB {GO:0005164=GO_REF:0000002, GO:0008284=PMID:10359578, GO:0001782=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0008283=PMID:10908663, GO:0030890=GO_REF:0000019, GO:0031296=GO_REF:0000019, GO:0031295=GO_REF:0000019, GO:0005102=PMID:10908663, GO:0005125=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0007165=PMID:10908663, GO:0006955=GO_REF:0000002, GO:0042102=GO_REF:0000019, GO:0002636=GO_REF:0000019, GO:0016021=PMID:12867412, GO:0048305=GO_REF:0000019} Q9Y275 Tumor necrosis factor ligand superfamily member 13B protein 20030904 {GO:0005164=IEA, GO:0008284=TAS, GO:0001782=IEA, GO:0005886=IEA, GO:0008283=TAS, GO:0030890=IEA, GO:0031296=IEA, GO:0031295=IEA, GO:0005102=TAS, GO:0005125=IEA, GO:0005615=IEA, GO:0007165=TAS, GO:0006955=IEA, GO:0042102=IEA, GO:0002636=IEA, GO:0016021=NAS, GO:0048305=IEA} B cell costimulation, B cell homeostasis, T cell costimulation, cell proliferation, immune response, immunoglobulin secretion, positive regulation of B cell proliferation, positive regulation of T cell proliferation, positive regulation of cell proliferation, positive regulation of germinal center formation, signal transduction extracellular space, integral to membrane, plasma membrane cytokine activity, receptor binding, tumor necrosis factor receptor binding Human TNFSF14 GOC UniProtKB {GO:0005515=PMID:10318773, GO:0005164=GO_REF:0000002, GO:0005886=GO_REF:0000039, GO:0005102=PMID:12393901, GO:0006917=PMID:10799510, GO:0005125=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0007165=PMID:12393901, GO:0006955=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0042110=PMID:12393901, GO:0008588=PMID:12393901, GO:0042098=PMID:9765287, GO:0016021=GO_REF:0000037, GO:0043154=PMID:12393901, GO:0071260=PMID:19593445, GO:0043029=PMID:12393901, GO:0043027=PMID:12393901} O43557 Tumor necrosis factor ligand superfamily member 14 protein 20130413 {GO:0005515=IPI, GO:0005164=IEA, GO:0005886=IEA, GO:0005102=IPI, GO:0006917=TAS, GO:0005125=IEA, GO:0005615=IEA, GO:0007165=NAS, GO:0006955=IEA, GO:0005737=IEA, GO:0042110=NAS, GO:0008588=IDA, GO:0042098=NAS, GO:0016021=IEA, GO:0043154=IDA, GO:0071260=IEP, GO:0043029=NAS, GO:0043027=IDA} T cell activation, T cell homeostasis, T cell proliferation, cellular response to mechanical stimulus, immune response, induction of apoptosis, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, release of cytoplasmic sequestered NF-kappaB, signal transduction cytoplasm, extracellular space, integral to membrane, plasma membrane cysteine-type endopeptidase inhibitor activity involved in apoptotic process, cytokine activity, protein binding, receptor binding, tumor necrosis factor receptor binding Human TNFSF15 MGI UniProtKB {GO:0005164=GO_REF:0000002, GO:0005886=PMID:11911831, GO:0007250=PMID:11911831, GO:0006919=PMID:11911831, GO:0005102=PMID:9434163, GO:0005123=GO_REF:0000019, GO:0050715=GO_REF:0000019, GO:0005125=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0007165=PMID:9872942, GO:0006955=GO_REF:0000002, GO:0005887=PMID:9872942, GO:0016021=PMID:9872942, GO:0042107=PMID:11911831} O95150 Tumor necrosis factor ligand superfamily member 15 protein 20030418 {GO:0005164=IEA, GO:0005886=IDA, GO:0007250=IDA, GO:0006919=IDA, GO:0005102=TAS, GO:0005123=IEA, GO:0050715=IEA, GO:0005125=IEA, GO:0005615=IEA, GO:0007165=NAS, GO:0006955=IEA, GO:0005887=TAS, GO:0016021=NAS, GO:0042107=IDA} activation of NF-kappaB-inducing kinase activity, activation of cysteine-type endopeptidase activity involved in apoptotic process, cytokine metabolic process, immune response, positive regulation of cytokine secretion, signal transduction extracellular space, integral to membrane, integral to plasma membrane, plasma membrane cytokine activity, death receptor binding, receptor binding, tumor necrosis factor receptor binding Human TNFSF18 PINC UniProtKB {GO:0005164=GO_REF:0000002, GO:0043066=PMID:10074428, GO:0005886=GO_REF:0000039, GO:0009986=GO_REF:0000024, GO:0007267=PMID:10074428, GO:0005102=PMID:10074428, GO:0032813=GO_REF:0000024, GO:0005125=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0033209=GO_REF:0000024, GO:0007165=PMID:10074428, GO:0002309=GO_REF:0000024, GO:0051092=GO_REF:0000024, GO:0042129=GO_REF:0000024, GO:0016021=GO_REF:0000037} Q9UNG2 Tumor necrosis factor ligand superfamily member 18 protein 20030904 {GO:0005164=IEA, GO:0043066=TAS, GO:0005886=IEA, GO:0009986=ISS, GO:0007267=TAS, GO:0005102=TAS, GO:0032813=ISS, GO:0005125=IEA, GO:0005615=IEA, GO:0033209=ISS, GO:0007165=TAS, GO:0002309=ISS, GO:0051092=ISS, GO:0042129=ISS, GO:0016021=IEA} T cell proliferation involved in immune response, cell-cell signaling, negative regulation of apoptotic process, positive regulation of NF-kappaB transcription factor activity, regulation of T cell proliferation, signal transduction, tumor necrosis factor-mediated signaling pathway cell surface, extracellular space, integral to membrane, plasma membrane cytokine activity, receptor binding, tumor necrosis factor receptor binding, tumor necrosis factor receptor superfamily binding Human TNFSF4 UniProtKB UniProtKB {GO:0032755=PMID:20844189, GO:0032753=PMID:18501882, GO:0032813=GO_REF:0000024, GO:0002215=GO_REF:0000024, GO:0042221=GO_REF:0000024, GO:0005615=GO_REF:0000038, GO:0046641=GO_REF:0000024, GO:0035708=GO_REF:0000024, GO:0032689=GO_REF:0000024, GO:0002891=GO_REF:0000024, GO:0035709=GO_REF:0000024, GO:0032729=PMID:18501882, GO:0005164=GO_REF:0000002, GO:0002526=GO_REF:0000024, GO:0009986=PMID:18397322, GO:0002726=GO_REF:0000024, GO:0005125=GO_REF:0000038, GO:0005887=PMID:18397322, GO:0035712=GO_REF:0000024, GO:0050871=GO_REF:0000024, GO:0002830=GO_REF:0000024, GO:0045892=GO_REF:0000024, GO:0045590=GO_REF:0000024, GO:0008284=PMID:7913952, GO:0032733=GO_REF:0000024, GO:0032735=GO_REF:0000024, GO:0032736=GO_REF:0000024, GO:1900281=GO_REF:0000024, GO:0050710=GO_REF:0000019, GO:0071380=PMID:19029446, GO:0043433=GO_REF:0000024, GO:0042104=GO_REF:0000019, GO:0006955=GO_REF:0000002, GO:0042098=GO_REF:0000019, GO:0043382=GO_REF:0000024, GO:0045630=GO_REF:0000024, GO:0008203=GO_REF:0000019, GO:0032743=GO_REF:0000019, GO:0005102=PMID:7913952, GO:0050727=GO_REF:0000024, GO:0009615=GO_REF:0000024, GO:0071954=GO_REF:0000024, GO:0032700=PMID:18501882, GO:0002819=GO_REF:0000024, GO:0007165=PMID:7913952, GO:0071222=PMID:20844189, GO:0016020=GO_REF:0000002, GO:0043372=GO_REF:0000024, GO:0051024=GO_REF:0000024, GO:0050729=PMID:20844189, GO:0045626=GO_REF:0000024} Q8IV74 cDNA FLJ50815, highly similar to Tumor necrosis factor ligand superfamilymember 4 protein 20130413 {GO:0032755=IDA, GO:0032753=IDA, GO:0032813=ISS, GO:0002215=ISS, GO:0042221=ISS, GO:0005615=IEA, GO:0046641=ISS, GO:0035708=ISS, GO:0032689=ISS, GO:0002891=ISS, GO:0035709=ISS, GO:0032729=IDA, GO:0005164=IEA, GO:0002526=ISS, GO:0009986=IDA, GO:0002726=ISS, GO:0005125=IEA, GO:0005887=NAS, GO:0035712=ISS, GO:0050871=ISS, GO:0002830=ISS, GO:0045892=ISS, GO:0045590=ISS, GO:0008284=TAS, GO:0032733=ISS, GO:0032735=ISS, GO:0032736=ISS, GO:1900281=ISS, GO:0050710=IEA, GO:0071380=IDA, GO:0043433=ISS, GO:0042104=IEA, GO:0006955=IEA, GO:0042098=IEA, GO:0043382=ISS, GO:0045630=ISS, GO:0008203=IEA, GO:0032743=IEA, GO:0005102=TAS, GO:0050727=ISS, GO:0009615=ISS, GO:0071954=ISS, GO:0032700=IDA, GO:0002819=ISS, GO:0007165=TAS, GO:0071222=IDA, GO:0016020=IEA, GO:0043372=ISS, GO:0051024=ISS, GO:0050729=IDA, GO:0045626=ISS} T cell proliferation, T-helper 2 cell activation, acute inflammatory response, cellular response to lipopolysaccharide, cellular response to prostaglandin E stimulus, chemokine (C-C motif) ligand 11 production, cholesterol metabolic process, defense response to nematode, immune response, interleukin-4-dependent isotype switching to IgE isotypes, memory T cell activation, negative regulation of T-helper 1 cell differentiation, negative regulation of cytokine secretion, negative regulation of interferon-gamma production, negative regulation of interleukin-17 production, negative regulation of regulatory T cell differentiation, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription, DNA-dependent, positive regulation of B cell activation, positive regulation of CD4-positive, alpha beta T cell costimulation, positive regulation of CD4-positive, alpha-beta T cell differentiation, positive regulation of T cell cytokine production, positive regulation of T-helper 2 cell differentiation, positive regulation of activated T cell proliferation, positive regulation of alpha-beta T cell proliferation, positive regulation of cell proliferation, positive regulation of immunoglobulin mediated immune response, positive regulation of immunoglobulin secretion, positive regulation of inflammatory response, positive regulation of interferon-gamma production, positive regulation of interleukin-10 production, positive regulation of interleukin-12 production, positive regulation of interleukin-13 production, positive regulation of interleukin-2 production, positive regulation of interleukin-4 production, positive regulation of interleukin-6 production, positive regulation of memory T cell differentiation, positive regulation of type 2 immune response, regulation of adaptive immune response, regulation of inflammatory response, response to chemical stimulus, response to virus, signal transduction cell surface, extracellular space, integral to plasma membrane, membrane cytokine activity, receptor binding, tumor necrosis factor receptor binding, tumor necrosis factor receptor superfamily binding Human UniProtKB-KW:KW-0202 TNFSF8 PINC UniProtKB {GO:0005164=GO_REF:0000002, GO:0050830=GO_REF:0000019, GO:0008283=PMID:8391931, GO:0005102=PMID:8391931, GO:0007267=PMID:8391931, GO:0006917=PMID:8391931, GO:0005125=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0007165=PMID:8391931, GO:0006955=GO_REF:0000002, GO:0043374=GO_REF:0000019, GO:0005887=PMID:8391931, GO:0045944=GO_REF:0000019} P32971 Tumor necrosis factor ligand superfamily member 8 protein 20030904 {GO:0005164=IEA, GO:0050830=IEA, GO:0008283=TAS, GO:0005102=TAS, GO:0007267=TAS, GO:0006917=TAS, GO:0005125=IEA, GO:0005615=IEA, GO:0007165=TAS, GO:0006955=IEA, GO:0043374=IEA, GO:0005887=TAS, GO:0045944=IEA} CD8-positive, alpha-beta T cell differentiation, cell proliferation, cell-cell signaling, defense response to Gram-positive bacterium, immune response, induction of apoptosis, positive regulation of transcription from RNA polymerase II promoter, signal transduction extracellular space, integral to plasma membrane cytokine activity, receptor binding, tumor necrosis factor receptor binding Human TNFSF9 PINC UniProtKB {GO:0007165=PMID:8088337, GO:0005164=GO_REF:0000002, GO:0006955=GO_REF:0000002, GO:0005886=GO_REF:0000019, GO:0008283=PMID:8088337, GO:0042127=GO_REF:0000019, GO:0007267=PMID:8088337, GO:0005102=PMID:8088337, GO:0006915=PMID:8088337, GO:0016021=GO_REF:0000037, GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000037} P41273 Tumor necrosis factor ligand superfamily member 9 protein 20030904 {GO:0007165=TAS, GO:0005164=IEA, GO:0006955=IEA, GO:0005886=IEA, GO:0008283=TAS, GO:0042127=IEA, GO:0007267=TAS, GO:0005102=TAS, GO:0006915=TAS, GO:0016021=IEA, GO:0005615=IEA, GO:0005125=IEA} apoptotic process, cell proliferation, cell-cell signaling, immune response, regulation of cell proliferation, signal transduction extracellular space, integral to membrane, plasma membrane cytokine activity, receptor binding, tumor necrosis factor receptor binding Human TNIK HPA UniProtKB {GO:0005515=PMID:18930710, GO:0031532=PMID:15342639, GO:0005730=GO_REF:0000052, GO:0006950=PMID:10521462, GO:0005634=GO_REF:0000052, GO:0007256=PMID:15342639, GO:0005524=GO_REF:0000029, GO:0007243=PMID:10521462, GO:0048814=PMID:20159449, GO:0005083=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0046777=PMID:15342639, GO:0004674=PMID:15342639, GO:0007010=PMID:10521462, GO:0006468=PMID:15342639, GO:0005856=PMID:15342639, GO:0016055=GO_REF:0000037, GO:0055037=GO_REF:0000039} Q9UKE5 TRAF2 and NCK-interacting protein kinase protein 20081203 {GO:0005515=IPI, GO:0031532=IDA, GO:0005730=IDA, GO:0006950=IDA, GO:0005634=IDA, GO:0007256=IDA, GO:0005524=NAS, GO:0007243=IDA, GO:0048814=IDA, GO:0005083=IEA, GO:0005737=IDA, GO:0046777=IDA, GO:0004674=IDA, GO:0007010=IMP, GO:0006468=IDA, GO:0005856=IDA, GO:0016055=IEA, GO:0055037=IEA} Wnt receptor signaling pathway, actin cytoskeleton reorganization, activation of JNKK activity, cytoskeleton organization, intracellular protein kinase cascade, protein autophosphorylation, protein phosphorylation, regulation of dendrite morphogenesis, response to stress cytoplasm, cytoskeleton, nucleolus, nucleus, recycling endosome ATP binding, protein binding, protein serine/threonine kinase activity, small GTPase regulator activity Human TNIP1 BHF-UCL UniProtKB {GO:0005515=PMID:15474016, GO:0004843=PMID:16684768, GO:0005634=GO_REF:0000039, GO:0006952=PMID:9923610, GO:0006412=PMID:9923610, GO:0005622=PMID:9923610, GO:0005737=GO_REF:0000052, GO:0006954=GO_REF:0000037, GO:0009101=PMID:9923610, GO:0045944=GO_REF:0000024, GO:0002755=GO_REF:0000024, GO:0050729=GO_REF:0000024, GO:0007159=PMID:17632516, GO:0070373=PMID:12220502, GO:0085032=PMID:20010814, GO:0043124=PMID:16684768, GO:0051019=PMID:12220502, GO:0045071=PMID:9923610} Q15025 TNFAIP3-interacting protein 1 protein 20110201 {GO:0005515=IPI, GO:0004843=IDA, GO:0005634=IEA, GO:0006952=TAS, GO:0006412=TAS, GO:0005622=TAS, GO:0005737=IDA, GO:0006954=IEA, GO:0009101=IDA, GO:0045944=ISS, GO:0002755=ISS, GO:0050729=ISS, GO:0007159=IMP, GO:0070373=IDA, GO:0085032=IDA, GO:0043124=IDA, GO:0051019=IDA, GO:0045071=TAS} MyD88-dependent toll-like receptor signaling pathway, defense response, glycoprotein biosynthetic process, inflammatory response, leukocyte cell-cell adhesion, modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade, negative regulation of ERK1 and ERK2 cascade, negative regulation of I-kappaB kinase/NF-kappaB cascade, negative regulation of viral genome replication, positive regulation of inflammatory response, positive regulation of transcription from RNA polymerase II promoter, translation cytoplasm, intracellular, nucleus mitogen-activated protein kinase binding, protein binding, ubiquitin-specific protease activity Human UniProtKB:P21580 TNIP2 BHF-UCL UniProtKB {GO:0005515=PMID:15474016, GO:0019901=PMID:21784860, GO:0043032=GO_REF:0000024, GO:0034134=GO_REF:0000024, GO:0023035=GO_REF:0000024, GO:0007249=GO_REF:0000019, GO:0050821=GO_REF:0000024, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037, GO:0005829=Reactome:REACT_22206, GO:0071222=GO_REF:0000024, GO:0006954=GO_REF:0000037, GO:0045944=PMID:12753905, GO:0050871=GO_REF:0000024, GO:0043123=PMID:21784860, GO:2000352=PMID:12933576, GO:0034138=GO_REF:0000024, GO:0070498=GO_REF:0000024, GO:0034162=GO_REF:0000024, GO:0031593=PMID:18212736} Q8NFZ5 TNFAIP3-interacting protein 2 protein 20110201 {GO:0005515=IPI, GO:0019901=IDA, GO:0043032=ISS, GO:0034134=ISS, GO:0023035=ISS, GO:0007249=IEA, GO:0050821=ISS, GO:0006915=IEA, GO:0005634=IEA, GO:0006351=IEA, GO:0005829=TAS, GO:0071222=ISS, GO:0006954=IEA, GO:0045944=IDA, GO:0050871=ISS, GO:0043123=IDA, GO:2000352=IDA, GO:0034138=ISS, GO:0070498=ISS, GO:0034162=ISS, GO:0031593=IDA} CD40 signaling pathway, I-kappaB kinase/NF-kappaB cascade, apoptotic process, cellular response to lipopolysaccharide, inflammatory response, interleukin-1-mediated signaling pathway, negative regulation of endothelial cell apoptotic process, positive regulation of B cell activation, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of macrophage activation, positive regulation of transcription from RNA polymerase II promoter, protein stabilization, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 9 signaling pathway, transcription, DNA-dependent cytosol, nucleus polyubiquitin binding, protein binding, protein kinase binding Human UniProtKB:P21580 TNIP3 UniProtKB UniProtKB {GO:0002756=PMID:17088249, GO:0071222=PMID:17088249, GO:0034142=PMID:17088249, GO:0006954=GO_REF:0000037, GO:0043124=PMID:17088249, GO:0031593=PMID:18212736} Q96KP6 TNFAIP3-interacting protein 3 protein 20120521 {GO:0002756=IDA, GO:0071222=IDA, GO:0034142=IDA, GO:0006954=IEA, GO:0043124=IDA, GO:0031593=IDA} MyD88-independent toll-like receptor signaling pathway, cellular response to lipopolysaccharide, inflammatory response, negative regulation of I-kappaB kinase/NF-kappaB cascade, toll-like receptor 4 signaling pathway polyubiquitin binding Human TNK1 GOC UniProtKB {GO:0005515=PMID:10873601, GO:0030308=GO_REF:0000019, GO:0005524=PMID:10873601, GO:0005829=GO_REF:0000019, GO:0046580=GO_REF:0000019, GO:0007165=PMID:8632913, GO:0005737=PMID:10873601, GO:0046777=PMID:10873601, GO:0016020=PMID:10873601, GO:0006468=PMID:8632913, GO:0004713=PMID:10873601, GO:0004871=PMID:8632913, GO:0004715=PMID:10873601} Q13470 Non-receptor tyrosine-protein kinase TNK1 protein 20130413 {GO:0005515=IPI, GO:0030308=IEA, GO:0005524=IDA, GO:0005829=IEA, GO:0046580=IEA, GO:0007165=TAS, GO:0005737=IDA, GO:0046777=IDA, GO:0016020=IDA, GO:0006468=TAS, GO:0004713=IDA, GO:0004871=TAS, GO:0004715=NAS} negative regulation of Ras protein signal transduction, negative regulation of cell growth, protein autophosphorylation, protein phosphorylation, signal transduction cytoplasm, cytosol, membrane ATP binding, non-membrane spanning protein tyrosine kinase activity, protein binding, protein tyrosine kinase activity, signal transducer activity Human TNK2 BHF-UCL UniProtKB {GO:0005515=PMID:11157984, GO:0030424=GO_REF:0000019, GO:0005154=PMID:20086093, GO:0005886=PMID:20979614, GO:0007264=PMID:8497321, GO:0030136=PMID:18262180, GO:0050731=PMID:10587647, GO:0005634=PMID:20333297, GO:0046872=GO_REF:0000037, GO:0030425=GO_REF:0000019, GO:0030426=GO_REF:0000019, GO:0005737=PMID:20979614, GO:0005912=GO_REF:0000039, GO:0043025=GO_REF:0000019, GO:2000369=PMID:18262180, GO:0030659=GO_REF:0000039, GO:0070436=PMID:20086093, GO:0050699=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0006897=GO_REF:0000037, GO:0016310=PMID:20979614, GO:0005905=PMID:21169560, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000037, GO:0004712=PMID:16257963, GO:0004713=PMID:18993068, GO:0005095=PMID:8497321, GO:0004715=GO_REF:0000003, GO:0007166=PMID:20432460, GO:0005768=GO_REF:0000024} Q07912 Activated CDC42 kinase 1 protein 20120308 {GO:0005515=IPI, GO:0030424=IEA, GO:0005154=IDA, GO:0005886=IDA, GO:0007264=TAS, GO:0030136=IDA, GO:0050731=IDA, GO:0005634=IDA, GO:0046872=IEA, GO:0030425=IEA, GO:0030426=IEA, GO:0005737=IDA, GO:0005912=IEA, GO:0043025=IEA, GO:2000369=IDA, GO:0030659=IEA, GO:0070436=IDA, GO:0050699=ISS, GO:0005524=IEA, GO:0006897=IEA, GO:0016310=IDA, GO:0005905=IDA, GO:0004672=IEA, GO:0004674=IEA, GO:0004712=IDA, GO:0004713=IDA, GO:0005095=TAS, GO:0004715=IEA, GO:0007166=TAS, GO:0005768=ISS} cell surface receptor signaling pathway, endocytosis, phosphorylation, positive regulation of peptidyl-tyrosine phosphorylation, regulation of clathrin-mediated endocytosis, small GTPase mediated signal transduction Grb2-EGFR complex, adherens junction, axon, clathrin-coated vesicle, coated pit, cytoplasm, cytoplasmic vesicle membrane, dendrite, endosome, growth cone, neuronal cell body, nucleus, plasma membrane ATP binding, GTPase inhibitor activity, WW domain binding, epidermal growth factor receptor binding, metal ion binding, non-membrane spanning protein tyrosine kinase activity, protein binding, protein kinase activity, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity, protein tyrosine kinase activity Human TNKS BHF-UCL UniProtKB {GO:0005515=PMID:19759537, GO:0090263=PMID:19759537, GO:0015031=GO_REF:0000037, GO:0003950=PMID:22864114, GO:0006471=PMID:9822378, GO:0032212=PMID:11739745, GO:0032210=PMID:9822378, GO:0018105=PMID:17026964, GO:0005643=PMID:11454873, GO:0045944=PMID:19245366, GO:0018107=PMID:17026964, GO:0007052=PMID:17026964, GO:0016055=GO_REF:0000037, GO:0000242=PMID:11454873, GO:0070198=PMID:18221737, GO:0000784=PMID:11739745, GO:0000209=PMID:19759537, GO:0031965=PMID:11454873, GO:0000781=PMID:9822378, GO:0005794=PMID:22864114, GO:0051225=PMID:17026964, GO:0043392=PMID:9822378, GO:0070213=PMID:9822378, GO:0070212=PMID:9822378, GO:0000922=GO_REF:0000039, GO:0007067=GO_REF:0000037, GO:0000139=GO_REF:0000039, GO:0008270=PMID:18436240, GO:0051028=GO_REF:0000037, GO:0000775=GO_REF:0000039, GO:0051301=GO_REF:0000037} O95271 Tankyrase-1 protein 20081217 {GO:0005515=IPI, GO:0090263=IMP, GO:0015031=IEA, GO:0003950=IDA, GO:0006471=IDA, GO:0032212=IMP, GO:0032210=IC, GO:0018105=IDA, GO:0005643=TAS, GO:0045944=IDA, GO:0018107=IDA, GO:0007052=TAS, GO:0016055=IEA, GO:0000242=TAS, GO:0070198=IMP, GO:0000784=IDA, GO:0000209=IDA, GO:0031965=TAS, GO:0000781=IDA, GO:0005794=IDA, GO:0051225=TAS, GO:0043392=IDA, GO:0070213=IDA, GO:0070212=IDA, GO:0000922=IEA, GO:0007067=IEA, GO:0000139=IEA, GO:0008270=IDA, GO:0051028=IEA, GO:0000775=IEA, GO:0051301=IEA} Wnt receptor signaling pathway, cell division, mRNA transport, mitosis, mitotic spindle organization, negative regulation of DNA binding, peptidyl-serine phosphorylation, peptidyl-threonine phosphorylation, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of telomere maintenance via telomerase, positive regulation of transcription from RNA polymerase II promoter, protein ADP-ribosylation, protein auto-ADP-ribosylation, protein localization to chromosome, telomeric region, protein poly-ADP-ribosylation, protein polyubiquitination, protein transport, regulation of telomere maintenance via telomerase, spindle assembly Golgi apparatus, Golgi membrane, chromosome, centromeric region, chromosome, telomeric region, nuclear chromosome, telomeric region, nuclear membrane, nuclear pore, pericentriolar material, spindle pole NAD+ ADP-ribosyltransferase activity, protein binding, zinc ion binding Human TNKS1BP1 Reactome UniProtKB {GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0030506=PMID:11854288, GO:0005634=PMID:11854288, GO:0030014=PMID:19558367, GO:0005829=Reactome:REACT_20651, GO:0005737=PMID:11854288, GO:0005724=PMID:11854288, GO:0005856=GO_REF:0000039, GO:0007004=PMID:11854288, GO:0019899=PMID:11854288, GO:0000289=Reactome:REACT_20514, GO:0000288=Reactome:REACT_20639} Q9C0C2 182 kDa tankyrase-1-binding protein protein 20090723 {GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0030506=NAS, GO:0005634=NAS, GO:0030014=IDA, GO:0005829=TAS, GO:0005737=NAS, GO:0005724=NAS, GO:0005856=IEA, GO:0007004=NAS, GO:0019899=NAS, GO:0000289=TAS, GO:0000288=TAS} RNA metabolic process, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA poly(A) tail shortening, telomere maintenance via telomerase CCR4-NOT complex, cytoplasm, cytoskeleton, cytosol, nuclear telomeric heterochromatin, nucleus ankyrin binding, enzyme binding Human TNKS2 BHF-UCL UniProtKB {GO:0005515=PMID:22153077, GO:0000209=PMID:21478859, GO:0048471=PMID:11454873, GO:0090263=PMID:19759537, GO:0005634=PMID:11739745, GO:0005635=PMID:11454873, GO:0046872=GO_REF:0000037, GO:0003950=PMID:11739745, GO:0006471=PMID:11739745, GO:0070213=PMID:21478859, GO:0032212=PMID:11739745, GO:0005737=PMID:11278563, GO:0035264=GO_REF:0000019, GO:0000139=GO_REF:0000039, GO:0040014=GO_REF:0000019, GO:0016055=GO_REF:0000037, GO:0019899=PMID:21251231, GO:0000242=PMID:11454873, GO:0070198=PMID:11739745, GO:0000784=PMID:11739745} Q9H2K2 Tankyrase-2 protein 20081217 {GO:0005515=IPI, GO:0000209=IDA, GO:0048471=IDA, GO:0090263=IMP, GO:0005634=IDA, GO:0005635=IDA, GO:0046872=IEA, GO:0003950=IDA, GO:0006471=IDA, GO:0070213=IDA, GO:0032212=IC, GO:0005737=IDA, GO:0035264=IEA, GO:0000139=IEA, GO:0040014=IEA, GO:0016055=IEA, GO:0019899=IPI, GO:0000242=IDA, GO:0070198=IMP, GO:0000784=IC} Wnt receptor signaling pathway, multicellular organism growth, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of telomere maintenance via telomerase, protein ADP-ribosylation, protein auto-ADP-ribosylation, protein localization to chromosome, telomeric region, protein polyubiquitination, regulation of multicellular organism growth Golgi membrane, cytoplasm, nuclear chromosome, telomeric region, nuclear envelope, nucleus, pericentriolar material, perinuclear region of cytoplasm NAD+ ADP-ribosyltransferase activity, enzyme binding, metal ion binding, protein binding Human TNN UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0005178=GO_REF:0000019, GO:0016477=GO_REF:0000024, GO:0009986=GO_REF:0000019, GO:0007160=GO_REF:0000019, GO:0005578=GO_REF:0000039, GO:0016049=GO_REF:0000024, GO:0005575=GO_REF:0000015, GO:0007409=GO_REF:0000019, GO:0042802=GO_REF:0000019} Q9UQP3 Tenascin-N protein 20041006 {GO:0003674=ND, GO:0005178=IEA, GO:0016477=ISS, GO:0009986=IEA, GO:0007160=IEA, GO:0005578=IEA, GO:0016049=ISS, GO:0005575=ND, GO:0007409=IEA, GO:0042802=IEA} axonogenesis, cell growth, cell migration, cell-matrix adhesion cell surface, cellular_component, proteinaceous extracellular matrix identical protein binding, integrin binding, molecular_function Human UniProtKB:Q80Z71 TNNC1 BHF-UCL UniProtKB {GO:0005515=PMID:10806205, GO:0005861=PMID:12093807, GO:0030049=Reactome:REACT_16969, GO:0055010=PMID:15542288, GO:0005509=PMID:12840750, GO:0060048=PMID:15542288, GO:0042803=PMID:18092822, GO:0005829=Reactome:REACT_17057, GO:0032972=GO_REF:0000024, GO:0006937=PMID:18092822, GO:0031014=PMID:15542288, GO:0051015=GO_REF:0000024, GO:0031013=PMID:18092822, GO:0043462=GO_REF:0000024, GO:0048306=PMID:7957210} P63316 Troponin C, slow skeletal and cardiac muscles protein 20080512 {GO:0005515=IPI, GO:0005861=IDA, GO:0030049=TAS, GO:0055010=IMP, GO:0005509=IDA, GO:0060048=IMP, GO:0042803=IDA, GO:0005829=TAS, GO:0032972=ISS, GO:0006937=IDA, GO:0031014=IPI, GO:0051015=ISS, GO:0031013=IDA, GO:0043462=ISS, GO:0048306=IPI} cardiac muscle contraction, muscle filament sliding, regulation of ATPase activity, regulation of muscle contraction, regulation of muscle filament sliding speed, ventricular cardiac muscle tissue morphogenesis cytosol, troponin complex actin filament binding, calcium ion binding, calcium-dependent protein binding, protein binding, protein homodimerization activity, troponin I binding, troponin T binding Human TNNC2 Reactome UniProtKB {GO:0006937=PMID:2373703, GO:0030049=Reactome:REACT_16969, GO:0005861=PMID:17194691, GO:0003009=PMID:17194691, GO:0005509=GO_REF:0000002, GO:0003779=PMID:17194691, GO:0005829=Reactome:REACT_17057} P02585 Troponin C, skeletal muscle protein 20130228 {GO:0006937=TAS, GO:0030049=TAS, GO:0005861=IDA, GO:0003009=IDA, GO:0005509=IEA, GO:0003779=IDA, GO:0005829=TAS} muscle filament sliding, regulation of muscle contraction, skeletal muscle contraction cytosol, troponin complex actin binding, calcium ion binding Human TNNI1 Reactome UniProtKB {GO:0030049=Reactome:REACT_16969, GO:0005861=GO_REF:0000029, GO:0055010=GO_REF:0000019, GO:0006942=PMID:2365354, GO:0003779=GO_REF:0000029, GO:0005523=GO_REF:0000029, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_17057} P19237 Troponin I, slow skeletal muscle protein 20130228 {GO:0030049=TAS, GO:0005861=NAS, GO:0055010=IEA, GO:0006942=NAS, GO:0003779=NAS, GO:0005523=NAS, GO:0046872=IEA, GO:0005829=TAS} muscle filament sliding, regulation of striated muscle contraction, ventricular cardiac muscle tissue morphogenesis cytosol, troponin complex actin binding, metal ion binding, tropomyosin binding Human TNNI2 Reactome UniProtKB {GO:0005515=PMID:18331830, GO:0031014=PMID:17194691, GO:0030049=Reactome:REACT_16969, GO:0005861=PMID:17194691, GO:0003009=PMID:17194691, GO:0003779=PMID:17194691, GO:0005634=PMID:18331830, GO:0045893=PMID:18331830, GO:0005829=Reactome:REACT_17057} P48788 Troponin I, fast skeletal muscle protein 20130228 {GO:0005515=IPI, GO:0031014=IPI, GO:0030049=TAS, GO:0005861=IDA, GO:0003009=IDA, GO:0003779=IDA, GO:0005634=IDA, GO:0045893=IDA, GO:0005829=TAS} muscle filament sliding, positive regulation of transcription, DNA-dependent, skeletal muscle contraction cytosol, nucleus, troponin complex actin binding, protein binding, troponin T binding Human TNNI3 BHF-UCL UniProtKB {GO:0005515=PMID:12721663, GO:0060047=PMID:12531876, GO:0030049=Reactome:REACT_16969, GO:0005861=PMID:12093807, GO:0055010=PMID:16754800, GO:0019901=PMID:12721663, GO:0019904=PMID:11984006, GO:0006874=GO_REF:0000024, GO:0001980=GO_REF:0000024, GO:0003779=PMID:10806205, GO:0032780=PMID:11735257, GO:0006940=GO_REF:0000019, GO:0030017=PMID:16754800, GO:0060048=PMID:11735257, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_17057, GO:0007507=GO_REF:0000024, GO:0030172=PMID:11735257, GO:0031014=PMID:15542288, GO:0019855=PMID:12809519, GO:0001570=GO_REF:0000024, GO:0048306=PMID:7957210} P19429 Troponin I, cardiac muscle protein 20080122 {GO:0005515=IPI, GO:0060047=IMP, GO:0030049=TAS, GO:0005861=IDA, GO:0055010=IMP, GO:0019901=IPI, GO:0019904=IPI, GO:0006874=ISS, GO:0001980=ISS, GO:0003779=IDA, GO:0032780=IDA, GO:0006940=IEA, GO:0030017=TAS, GO:0060048=IMP, GO:0046872=IEA, GO:0005829=TAS, GO:0007507=ISS, GO:0030172=IPI, GO:0031014=IPI, GO:0019855=IPI, GO:0001570=ISS, GO:0048306=IPI} cardiac muscle contraction, cellular calcium ion homeostasis, heart contraction, heart development, muscle filament sliding, negative regulation of ATPase activity, regulation of smooth muscle contraction, regulation of systemic arterial blood pressure by ischemic conditions, vasculogenesis, ventricular cardiac muscle tissue morphogenesis cytosol, sarcomere, troponin complex actin binding, calcium channel inhibitor activity, calcium-dependent protein binding, metal ion binding, protein binding, protein domain specific binding, protein kinase binding, troponin C binding, troponin T binding Human TNNI3K IntAct UniProtKB {GO:0005515=PMID:12721663, GO:0005737=PMID:12721663, GO:0031013=PMID:12721663, GO:0004672=PMID:12721663, GO:0004674=GO_REF:0000037, GO:0005634=PMID:12721663, GO:0006468=PMID:12721663, GO:0008022=PMID:18205602, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q59H18 Serine/threonine-protein kinase TNNI3K protein 20130415 {GO:0005515=IPI, GO:0005737=IDA, GO:0031013=IPI, GO:0004672=IDA, GO:0004674=IEA, GO:0005634=IDA, GO:0006468=IDA, GO:0008022=IPI, GO:0005524=IEA, GO:0046872=IEA} protein phosphorylation cytoplasm, nucleus ATP binding, metal ion binding, protein C-terminus binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, troponin I binding Human UniProtKB:P19429 TNNT1 InterPro UniProtKB {GO:0030049=Reactome:REACT_16969, GO:0045932=PMID:18032382, GO:0005861=GO_REF:0000002, GO:0003009=PMID:10952871, GO:0005523=PMID:15665378, GO:0005829=Reactome:REACT_17057} Q3B759 TNNT1 protein protein 20130413 {GO:0030049=TAS, GO:0045932=IDA, GO:0005861=IEA, GO:0003009=IMP, GO:0005523=IMP, GO:0005829=TAS} muscle filament sliding, negative regulation of muscle contraction, skeletal muscle contraction cytosol, troponin complex tropomyosin binding Human InterPro:IPR001978 TNNT2 BHF-UCL UniProtKB {GO:0005861=PMID:12186860, GO:0030049=Reactome:REACT_16969, GO:0055010=PMID:16754800, GO:0008016=PMID:15542288, GO:0045214=GO_REF:0000019, GO:0003779=PMID:8205619, GO:0032780=PMID:10850966, GO:0032781=PMID:12186860, GO:0030017=PMID:16754800, GO:0005829=Reactome:REACT_17057, GO:0051592=PMID:8205619, GO:0030172=PMID:15542288, GO:0031013=PMID:15542288, GO:0005865=PMID:12186860, GO:0005200=GO_REF:0000019, GO:0005523=PMID:10850966, GO:0055009=GO_REF:0000019} P45379 Troponin T, cardiac muscle protein 20080122 {GO:0005861=IDA, GO:0030049=TAS, GO:0055010=IMP, GO:0008016=IMP, GO:0045214=IEA, GO:0003779=IDA, GO:0032780=IDA, GO:0032781=IDA, GO:0030017=TAS, GO:0005829=TAS, GO:0051592=IMP, GO:0030172=IPI, GO:0031013=IPI, GO:0005865=IDA, GO:0005200=IEA, GO:0005523=IDA, GO:0055009=IEA} atrial cardiac muscle tissue morphogenesis, muscle filament sliding, negative regulation of ATPase activity, positive regulation of ATPase activity, regulation of heart contraction, response to calcium ion, sarcomere organization, ventricular cardiac muscle tissue morphogenesis cytosol, sarcomere, striated muscle thin filament, troponin complex actin binding, structural constituent of cytoskeleton, tropomyosin binding, troponin C binding, troponin I binding Human TNNT3 Reactome UniProtKB {GO:0030172=PMID:8987992, GO:0030049=Reactome:REACT_16969, GO:0031013=PMID:8987992, GO:0005861=PMID:8987992, GO:0003009=PMID:17194691, GO:0043462=PMID:17194691, GO:0006942=PMID:17194691, GO:0003779=PMID:17194691, GO:0030899=PMID:8987992, GO:0005523=PMID:9724539, GO:0005829=Reactome:REACT_17057, GO:0048306=PMID:8987992} P45378 Troponin T, fast skeletal muscle protein 20130228 {GO:0030172=IPI, GO:0030049=TAS, GO:0031013=IPI, GO:0005861=IDA, GO:0003009=IDA, GO:0043462=IDA, GO:0006942=IDA, GO:0003779=IDA, GO:0030899=IDA, GO:0005523=IDA, GO:0005829=TAS, GO:0048306=IDA} muscle filament sliding, regulation of ATPase activity, regulation of striated muscle contraction, skeletal muscle contraction cytosol, troponin complex actin binding, calcium-dependent ATPase activity, calcium-dependent protein binding, tropomyosin binding, troponin C binding, troponin I binding Human TNP1 UniProtKB UniProtKB {GO:0000012=PMID:12743712, GO:0006342=PMID:11315969, GO:0007289=PMID:12743712, GO:0035042=PMID:12743712, GO:0007286=PMID:12743712, GO:0007290=PMID:10781074, GO:0007275=GO_REF:0000037, GO:0006337=PMID:10781074, GO:0030317=PMID:10781074, GO:0003677=PMID:12743712, GO:0019953=PMID:10781074, GO:0006338=PMID:12743712, GO:0001673=GO_REF:0000019, GO:0000786=PMID:12743712, GO:0045892=PMID:12743712} P09430 Spermatid nuclear transition protein 1 protein 20040430 {GO:0000012=IDA, GO:0006342=IEP, GO:0007289=TAS, GO:0035042=TAS, GO:0007286=IDA, GO:0007290=IMP, GO:0007275=IEA, GO:0006337=IMP, GO:0030317=IMP, GO:0003677=IMP, GO:0019953=IMP, GO:0006338=IDA, GO:0001673=IEA, GO:0000786=IDA, GO:0045892=IDA} chromatin remodeling, chromatin silencing, fertilization, exchange of chromosomal proteins, multicellular organismal development, negative regulation of transcription, DNA-dependent, nucleosome disassembly, sexual reproduction, single strand break repair, sperm motility, spermatid development, spermatid nucleus differentiation, spermatid nucleus elongation male germ cell nucleus, nucleosome DNA binding Human TNP2 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039, GO:0007341=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0030317=GO_REF:0000019, GO:0007340=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0007339=GO_REF:0000019, GO:0000786=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q05952 Nuclear transition protein 2 protein 20130413 {GO:0005634=IEA, GO:0007341=IEA, GO:0007275=IEA, GO:0030317=IEA, GO:0007340=IEA, GO:0007283=IEA, GO:0007339=IEA, GO:0000786=IEA, GO:0003677=IEA, GO:0046872=IEA, GO:0030154=IEA} acrosome reaction, binding of sperm to zona pellucida, cell differentiation, multicellular organismal development, penetration of zona pellucida, sperm motility, spermatogenesis nucleosome, nucleus DNA binding, metal ion binding Human UniProtKB-SubCell:SL-0191 TNPO1 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0010467=Reactome:REACT_71, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0005634=PMID:9144189, GO:0006886=GO_REF:0000002, GO:0005829=Reactome:REACT_25366, GO:0005737=PMID:9144189, GO:0005643=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0008565=GO_REF:0000002, GO:0008139=PMID:8808633, GO:0000060=PMID:9144189} Q92973 Transportin-1 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0005634=TAS, GO:0006886=IEA, GO:0005829=TAS, GO:0005737=TAS, GO:0005643=IEA, GO:0019048=IEA, GO:0008565=IEA, GO:0008139=TAS, GO:0000060=TAS} RNA metabolic process, gene expression, intracellular protein transport, mRNA metabolic process, protein import into nucleus, translocation, virus-host interaction cytoplasm, cytosol, nuclear pore, nucleus nuclear localization sequence binding, protein binding, protein transporter activity Human UniProtKB:P62993 TNPO2 UniProtKB UniProtKB {GO:0005515=PMID:12896982, GO:0005737=GO_REF:0000039, GO:0005643=GO_REF:0000002, GO:0008565=GO_REF:0000002, GO:0008139=PMID:9298975, GO:0005634=PMID:9298975, GO:0006886=GO_REF:0000002} O14787 Transportin-2 protein 20120708 {GO:0005515=IPI, GO:0005737=IEA, GO:0005643=IEA, GO:0008565=IEA, GO:0008139=TAS, GO:0005634=TAS, GO:0006886=IEA} intracellular protein transport cytoplasm, nuclear pore, nucleus nuclear localization sequence binding, protein binding, protein transporter activity Human UniProtKB:Q9NQ94 TNPO3 HPA UniProtKB {GO:0005515=PMID:12628928, GO:0035048=PMID:12628928, GO:0005737=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0006810=GO_REF:0000038, GO:0004872=PMID:10366588, GO:0005634=GO_REF:0000052, GO:0043231=GO_REF:0000052} Q9Y5L0 Transportin-3 protein 20110516 {GO:0005515=IPI, GO:0035048=IDA, GO:0005737=IEA, GO:0005730=IDA, GO:0006810=IEA, GO:0004872=TAS, GO:0005634=IDA, GO:0043231=IDA} splicing factor protein import into nucleus, transport cytoplasm, intracellular membrane-bounded organelle, nucleolus, nucleus protein binding, receptor activity Human TNR HPA UniProtKB {GO:0008306=GO_REF:0000019, GO:0072534=GO_REF:0000019, GO:0022408=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0051968=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005578=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0060291=GO_REF:0000019, GO:0022029=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0050808=GO_REF:0000019, GO:0007411=PMID:8940128, GO:0030198=GO_REF:0000019, GO:0048692=GO_REF:0000019, GO:0050805=GO_REF:0000019, GO:0050885=GO_REF:0000019, GO:0045121=GO_REF:0000019, GO:0007155=PMID:8940128, GO:0007158=GO_REF:0000019, GO:0035641=GO_REF:0000019} Q92752 Tenascin-R protein 20101115 {GO:0008306=IEA, GO:0072534=IEA, GO:0022408=IEA, GO:0009986=IEA, GO:0051968=IEA, GO:0005730=IDA, GO:0005578=IEA, GO:0005634=IDA, GO:0060291=IEA, GO:0022029=IEA, GO:0005737=IDA, GO:0050808=IEA, GO:0007411=NAS, GO:0030198=IEA, GO:0048692=IEA, GO:0050805=IEA, GO:0050885=IEA, GO:0045121=IEA, GO:0007155=NAS, GO:0007158=IEA, GO:0035641=IEA} associative learning, axon guidance, cell adhesion, extracellular matrix organization, locomotory exploration behavior, long-term synaptic potentiation, negative regulation of axon extension involved in regeneration, negative regulation of cell-cell adhesion, negative regulation of synaptic transmission, neuromuscular process controlling balance, neuron cell-cell adhesion, positive regulation of synaptic transmission, glutamatergic, synapse organization, telencephalon cell migration cell surface, cytoplasm, membrane raft, nucleolus, nucleus, perineuronal net, proteinaceous extracellular matrix Human TNRC18 InterPro UniProtKB {GO:0003677=GO_REF:0000002} O15417 Trinucleotide repeat-containing gene 18 protein protein 20130413 {GO:0003677=IEA} DNA binding Human InterPro:IPR001025 TNRC6A IntAct UniProtKB {GO:0005515=PMID:21981923, GO:0010467=Reactome:REACT_71, GO:0048011=Reactome:REACT_11061, GO:0048015=Reactome:REACT_12464, GO:0003723=GO_REF:0000037, GO:0031047=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0035068=PMID:17671087, GO:0005829=Reactome:REACT_147761, GO:0035278=PMID:17671087, GO:0000166=GO_REF:0000002, GO:0007173=Reactome:REACT_9417, GO:0007219=Reactome:REACT_299, GO:0000932=PMID:20616046, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0009267=GO_REF:0000019} Q8NDV7 Trinucleotide repeat-containing gene 6A protein protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0048011=TAS, GO:0048015=TAS, GO:0003723=IEA, GO:0031047=IEA, GO:0003676=IEA, GO:0035068=IDA, GO:0005829=TAS, GO:0035278=IDA, GO:0000166=IEA, GO:0007173=TAS, GO:0007219=TAS, GO:0000932=IDA, GO:0008543=TAS, GO:0045087=TAS, GO:0009267=IEA} Notch signaling pathway, cellular response to starvation, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, gene expression, gene silencing by RNA, innate immune response, negative regulation of translation involved in gene silencing by miRNA, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling cytoplasmic mRNA processing body, cytosol, micro-ribonucleoprotein complex RNA binding, nucleic acid binding, nucleotide binding, protein binding Human UniProtKB:Q58A45 TNRC6B IntAct UniProtKB {GO:0005515=PMID:21981923, GO:0010467=Reactome:REACT_71, GO:0048011=Reactome:REACT_11061, GO:0048015=Reactome:REACT_12464, GO:0003723=GO_REF:0000037, GO:0060213=PMID:19716330, GO:0031047=PMID:19716330, GO:0006417=GO_REF:0000037, GO:0005829=Reactome:REACT_147761, GO:0000166=GO_REF:0000002, GO:0007173=Reactome:REACT_9417, GO:0007219=Reactome:REACT_299, GO:1900153=PMID:19716330, GO:0008543=Reactome:REACT_9470, GO:0000932=GO_REF:0000039, GO:0045087=Reactome:REACT_6802} Q9UPQ9 Trinucleotide repeat-containing gene 6B protein protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0048011=TAS, GO:0048015=TAS, GO:0003723=IEA, GO:0060213=IMP, GO:0031047=IMP, GO:0006417=IEA, GO:0005829=TAS, GO:0000166=IEA, GO:0007173=TAS, GO:0007219=TAS, GO:1900153=IMP, GO:0008543=TAS, GO:0000932=IEA, GO:0045087=TAS} Notch signaling pathway, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, gene expression, gene silencing by RNA, innate immune response, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, positive regulation of nuclear-transcribed mRNA poly(A) tail shortening, regulation of translation cytoplasmic mRNA processing body, cytosol RNA binding, nucleotide binding, protein binding Human UniProtKB:Q58A45 TNRC6C IntAct UniProtKB {GO:0005515=PMID:21981923, GO:0010467=Reactome:REACT_71, GO:0048011=Reactome:REACT_11061, GO:0001706=GO_REF:0000019, GO:0048015=Reactome:REACT_12464, GO:0003723=GO_REF:0000037, GO:0060213=PMID:21984185, GO:0031047=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0005829=Reactome:REACT_147761, GO:0060964=GO_REF:0000019, GO:0035278=PMID:21984184, GO:0007173=Reactome:REACT_9417, GO:0007219=Reactome:REACT_299, GO:0000166=GO_REF:0000002, GO:0008543=Reactome:REACT_9470, GO:1900153=PMID:21984185, GO:0045087=Reactome:REACT_6802, GO:0035162=GO_REF:0000019} Q9HCJ0 Trinucleotide repeat-containing gene 6C protein protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0048011=TAS, GO:0001706=IEA, GO:0048015=TAS, GO:0003723=IEA, GO:0060213=IDA, GO:0031047=IEA, GO:0003676=IEA, GO:0005829=TAS, GO:0060964=IEA, GO:0035278=TAS, GO:0007173=TAS, GO:0007219=TAS, GO:0000166=IEA, GO:0008543=TAS, GO:1900153=IDA, GO:0045087=TAS, GO:0035162=IEA} Notch signaling pathway, embryonic hemopoiesis, endoderm formation, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, gene expression, gene silencing by RNA, innate immune response, negative regulation of translation involved in gene silencing by miRNA, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, positive regulation of nuclear-transcribed mRNA poly(A) tail shortening, regulation of gene silencing by miRNA cytosol RNA binding, nucleic acid binding, nucleotide binding, protein binding Human UniProtKB:Q9ULM6 TNS1 HPA UniProtKB {GO:0005515=PMID:17190795, GO:0035556=GO_REF:0000002, GO:0010761=GO_REF:0000019, GO:0005737=GO_REF:0000037, GO:0030055=GO_REF:0000019, GO:0007044=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0005856=GO_REF:0000039, GO:0005925=GO_REF:0000052, GO:0046872=GO_REF:0000038} Q9HBL0 Tensin-1 protein 20111111 {GO:0005515=IPI, GO:0035556=IEA, GO:0010761=IEA, GO:0005737=IEA, GO:0030055=IEA, GO:0007044=IEA, GO:0003779=IEA, GO:0005856=IEA, GO:0005925=IDA, GO:0046872=IEA} cell-substrate junction assembly, fibroblast migration, intracellular signal transduction cell-substrate junction, cytoplasm, cytoskeleton, focal adhesion actin binding, metal ion binding, protein binding Human TNS3 IntAct UniProtKB {GO:0005515=PMID:19732724, GO:0035556=GO_REF:0000002, GO:0008284=GO_REF:0000019, GO:0048286=GO_REF:0000019, GO:0016477=GO_REF:0000019, GO:0005925=GO_REF:0000039, GO:0046872=GO_REF:0000038} Q68CZ2 Tensin-3 protein 20130415 {GO:0005515=IPI, GO:0035556=IEA, GO:0008284=IEA, GO:0048286=IEA, GO:0016477=IEA, GO:0005925=IEA, GO:0046872=IEA} cell migration, intracellular signal transduction, lung alveolus development, positive regulation of cell proliferation focal adhesion metal ion binding, protein binding Human UniProtKB:P12931 TNS4 UniProtKB UniProtKB {GO:0005515=PMID:17190795, GO:0005737=GO_REF:0000037, GO:0008104=PMID:17190795, GO:0006915=GO_REF:0000037, GO:0003779=GO_REF:0000037, GO:0005856=GO_REF:0000039, GO:0005925=PMID:17190795} Q8IZW8 Tensin-4 protein 20080509 {GO:0005515=IPI, GO:0005737=IEA, GO:0008104=IDA, GO:0006915=IEA, GO:0003779=IEA, GO:0005856=IEA, GO:0005925=IDA} apoptotic process, protein localization cytoplasm, cytoskeleton, focal adhesion actin binding, protein binding Human UniProtKB:Q96QB1 TNXB BHF-UCL UniProtKB {GO:0030036=GO_REF:0000024, GO:0005518=GO_REF:0000019, GO:0005578=PMID:7686164, GO:0005583=PMID:16278880, GO:0031012=PMID:22261194, GO:0005622=PMID:15102077, GO:0016337=GO_REF:0000019, GO:0005178=GO_REF:0000024, GO:0007160=GO_REF:0000019, GO:0030199=GO_REF:0000019, GO:0006631=GO_REF:0000019, GO:0032963=PMID:15102077, GO:0006641=GO_REF:0000019, GO:0043506=GO_REF:0000019, GO:0043206=GO_REF:0000019, GO:0007155=GO_REF:0000024, GO:0008201=GO_REF:0000024, GO:0048251=PMID:15102077} P22105 Tenascin-X protein 20120228 {GO:0030036=ISS, GO:0005518=IEA, GO:0005578=NAS, GO:0005583=IDA, GO:0031012=ISS, GO:0005622=IDA, GO:0016337=IEA, GO:0005178=ISS, GO:0007160=IEA, GO:0030199=IEA, GO:0006631=IEA, GO:0032963=IMP, GO:0006641=IEA, GO:0043506=IEA, GO:0043206=IEA, GO:0007155=ISS, GO:0008201=ISS, GO:0048251=IMP} actin cytoskeleton organization, cell adhesion, cell-cell adhesion, cell-matrix adhesion, collagen fibril organization, collagen metabolic process, elastic fiber assembly, extracellular fibril organization, fatty acid metabolic process, regulation of JUN kinase activity, triglyceride metabolic process extracellular matrix, fibrillar collagen, intracellular, proteinaceous extracellular matrix collagen binding, heparin binding, integrin binding colocalizes_with Human UniProtKB:A5A8W4 TOB1 PINC UniProtKB {GO:0017148=PMID:23236473, GO:0030514=GO_REF:0000019, GO:0030971=PMID:8632892, GO:0005737=GO_REF:0000019, GO:0008285=PMID:19276069, GO:0045668=GO_REF:0000019, GO:0005070=PMID:8632892, GO:0060212=PMID:18377426, GO:0007184=GO_REF:0000019, GO:0003714=GO_REF:0000019, GO:0046332=GO_REF:0000019} P50616 Protein Tob1 protein 20030904 {GO:0017148=IDA, GO:0030514=IEA, GO:0030971=IDA, GO:0005737=IEA, GO:0008285=IDA, GO:0045668=IEA, GO:0005070=TAS, GO:0060212=IDA, GO:0007184=IEA, GO:0003714=IEA, GO:0046332=IEA} SMAD protein import into nucleus, negative regulation of BMP signaling pathway, negative regulation of cell proliferation, negative regulation of nuclear-transcribed mRNA poly(A) tail shortening, negative regulation of osteoblast differentiation, negative regulation of translation cytoplasm SH3/SH2 adaptor activity, SMAD binding, receptor tyrosine kinase binding, transcription corepressor activity Human TOB2 PINC UniProtKB {GO:0010468=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0008285=PMID:10602502, GO:0042809=GO_REF:0000019, GO:0005634=PMID:10602502, GO:0045671=GO_REF:0000019, GO:0007292=PMID:10602502, GO:0045778=GO_REF:0000019} Q14106 Protein Tob2 protein 20030904 {GO:0010468=IEA, GO:0005737=IEA, GO:0008285=TAS, GO:0042809=IEA, GO:0005634=TAS, GO:0045671=IEA, GO:0007292=TAS, GO:0045778=IEA} female gamete generation, negative regulation of cell proliferation, negative regulation of osteoclast differentiation, positive regulation of ossification, regulation of gene expression cytoplasm, nucleus vitamin D receptor binding Human TOE1 UniProtKB UniProtKB {GO:0016607=GO_REF:0000039, GO:0005730=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q96GM8 Target of EGR1 protein 1 protein 20130413 {GO:0016607=IEA, GO:0005730=IEA, GO:0008270=IEA, GO:0005634=IEA, GO:0003676=IEA} nuclear speck, nucleolus, nucleus nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0186 TOLLIP IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0032183=GO_REF:0000019, GO:0048471=GO_REF:0000019, GO:0007267=PMID:10854325, GO:0005150=GO_REF:0000019, GO:0005829=Reactome:REACT_22435, GO:0035325=PMID:11441107, GO:0035556=PMID:10854325, GO:0016310=PMID:1085432, GO:0007165=PMID:11441107, GO:0016604=GO_REF:0000019, GO:0045323=PMID:10854325, GO:0005737=PMID:11441107, GO:0006954=PMID:10854325, GO:0045092=PMID:10854325, GO:0045321=PMID:11441107, GO:0045087=GO_REF:0000037, GO:0033235=GO_REF:0000019, GO:0004871=PMID:11441107, GO:0019900=PMID:10854325, GO:0031625=GO_REF:0000019, GO:0031624=GO_REF:0000019} Q9H0E2 Toll-interacting protein protein 20130415 {GO:0005515=IPI, GO:0032183=IEA, GO:0048471=IEA, GO:0007267=TAS, GO:0005150=IEA, GO:0005829=TAS, GO:0035325=IPI, GO:0035556=NAS, GO:0016310=IDA, GO:0007165=IPI, GO:0016604=IEA, GO:0045323=NAS, GO:0005737=IC, GO:0006954=NAS, GO:0045092=NAS, GO:0045321=NAS, GO:0045087=IEA, GO:0033235=IEA, GO:0004871=NAS, GO:0019900=IPI, GO:0031625=IEA, GO:0031624=IEA} cell-cell signaling, inflammatory response, innate immune response, intracellular signal transduction, leukocyte activation, phosphorylation, positive regulation of protein sumoylation, signal transduction cytoplasm, cytosol, interleukin-1 receptor complex, interleukin-18 receptor complex, nuclear body, perinuclear region of cytoplasm SUMO binding, Toll-like receptor binding, interleukin-1, Type I receptor binding, kinase binding, protein binding, signal transducer activity, ubiquitin conjugating enzyme binding, ubiquitin protein ligase binding Human UniProtKB:O75674 TOM1 UniProtKB UniProtKB {GO:0005515=PMID:14613930, GO:0005622=GO_REF:0000002, GO:0016020=PMID:14613930, GO:0016197=PMID:14613930, GO:0015031=PMID:14613930, GO:0006886=GO_REF:0000002, GO:0005769=PMID:14613930, GO:0005829=PMID:14613930, GO:0006897=PMID:10329004} O60784 Target of Myb protein 1 protein 20050707 {GO:0005515=IPI, GO:0005622=IEA, GO:0016020=IDA, GO:0016197=NAS, GO:0015031=NAS, GO:0006886=IEA, GO:0005769=IDA, GO:0005829=IDA, GO:0006897=NAS} endocytosis, endosomal transport, intracellular protein transport, protein transport cytosol, early endosome, intracellular, membrane protein binding Human UniProtKB:Q7Z3T8 TOM1L1 InterPro UniProtKB {GO:0005515=PMID:21988832, GO:0005622=GO_REF:0000002, GO:0043130=PMID:15611048, GO:0017124=GO_REF:0000037, GO:0005795=GO_REF:0000039, GO:0030295=GO_REF:0000002, GO:0043162=PMID:15611048, GO:0005764=PMID:10329004, GO:0006886=GO_REF:0000002, GO:0010008=GO_REF:0000039, GO:0005768=PMID:15611048, GO:0005829=PMID:15611048} Q8N749 TOM1-like protein 1 protein 20130413 {GO:0005515=IPI, GO:0005622=IEA, GO:0043130=TAS, GO:0017124=IEA, GO:0005795=IEA, GO:0030295=IEA, GO:0043162=NAS, GO:0005764=TAS, GO:0006886=IEA, GO:0010008=IEA, GO:0005768=IDA, GO:0005829=IDA} intracellular protein transport, ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway Golgi stack, cytosol, endosome, endosome membrane, intracellular, lysosome SH3 domain binding, protein binding, protein kinase activator activity, ubiquitin binding Human InterPro:IPR027428 TOM1L2 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0006886=GO_REF:0000002} Q6ZVM7 TOM1-like protein 2 protein 20130413 {GO:0005622=IEA, GO:0006886=IEA} intracellular protein transport intracellular Human InterPro:IPR002014|InterPro:IPR004152 TOMM20 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005515=PMID:14557246, GO:0015450=PMID:14557246, GO:0006626=Reactome:REACT_118595, GO:0005742=PMID:15644312, GO:0051082=PMID:14557246, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015} Q15388 Mitochondrial import receptor subunit TOM20 homolog protein 20080818 {GO:0005739=IDA, GO:0005515=IPI, GO:0015450=IDA, GO:0006626=TAS, GO:0005742=TAS, GO:0051082=IDA, GO:0016021=IEA, GO:0044267=TAS} cellular protein metabolic process, protein targeting to mitochondrion integral to membrane, mitochondrial outer membrane translocase complex, mitochondrion P-P-bond-hydrolysis-driven protein transmembrane transporter activity, protein binding, unfolded protein binding Human TOMM22 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005515=PMID:14557246, GO:0006626=Reactome:REACT_118595, GO:0005743=GO_REF:0000019, GO:0005742=PMID:15644312, GO:0008320=GO_REF:0000024, GO:0016021=PMID:15644312, GO:0045040=PMID:15644312, GO:0044267=Reactome:REACT_17015} Q9NS69 Mitochondrial import receptor subunit TOM22 homolog protein 20080205 {GO:0005739=IDA, GO:0005515=IPI, GO:0006626=TAS, GO:0005743=IEA, GO:0005742=IDA, GO:0008320=ISS, GO:0016021=IDA, GO:0045040=IDA, GO:0044267=TAS} cellular protein metabolic process, protein import into mitochondrial outer membrane, protein targeting to mitochondrion integral to membrane, mitochondrial inner membrane, mitochondrial outer membrane translocase complex, mitochondrion protein binding, protein transmembrane transporter activity Human TOMM34 PINC UniProtKB {GO:0031072=PMID:9660753, GO:0006626=PMID:9324309, GO:0005741=PMID:9324309, GO:0016021=PMID:9324309} Q15785 Mitochondrial import receptor subunit TOM34 protein 20030904 {GO:0031072=IPI, GO:0006626=IMP, GO:0005741=IDA, GO:0016021=TAS} protein targeting to mitochondrion integral to membrane, mitochondrial outer membrane heat shock protein binding Human TOMM40 BHF-UCL UniProtKB {GO:0005739=PMID:11745481, GO:0046930=GO_REF:0000037, GO:0006626=Reactome:REACT_118595, GO:0005742=PMID:12198123, GO:0015288=GO_REF:0000037, GO:0005741=GO_REF:0000002, GO:0008320=GO_REF:0000024, GO:0016021=PMID:15644312, GO:0031307=PMID:10980201, GO:0044267=Reactome:REACT_17015, GO:0055085=GO_REF:0000002, GO:0006811=GO_REF:0000037} O96008 Mitochondrial import receptor subunit TOM40 homolog protein 20081107 {GO:0005739=IMP, GO:0046930=IEA, GO:0006626=TAS, GO:0005742=IDA, GO:0015288=IEA, GO:0005741=IEA, GO:0008320=ISS, GO:0016021=IDA, GO:0031307=ISS, GO:0044267=TAS, GO:0055085=IEA, GO:0006811=IEA} cellular protein metabolic process, ion transport, protein targeting to mitochondrion, transmembrane transport integral to membrane, integral to mitochondrial outer membrane, mitochondrial outer membrane, mitochondrial outer membrane translocase complex, mitochondrion, pore complex porin activity, protein transmembrane transporter activity Human UniProtKB:Q75Q40 TOMM40L BHF-UCL UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0043234=GO_REF:0000054, GO:0046930=GO_REF:0000037, GO:0015288=GO_REF:0000037, GO:0005741=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0055085=GO_REF:0000002, GO:0006811=GO_REF:0000037} Q969M1 Mitochondrial import receptor subunit TOM40B protein 20110708 {GO:0003674=ND, GO:0008150=ND, GO:0043234=IDA, GO:0046930=IEA, GO:0015288=IEA, GO:0005741=IEA, GO:0015031=IEA, GO:0055085=IEA, GO:0006811=IEA} biological_process, ion transport, protein transport, transmembrane transport mitochondrial outer membrane, pore complex, protein complex molecular_function, porin activity Human TOMM5 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0008565=PMID:18331822, GO:0006626=Reactome:REACT_118595, GO:0005742=PMID:18331822, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015} Q8N4H5 Mitochondrial import receptor subunit TOM5 homolog protein 20120912 {GO:0005739=IDA, GO:0008565=IC, GO:0006626=TAS, GO:0005742=IDA, GO:0016021=IEA, GO:0044267=TAS} cellular protein metabolic process, protein targeting to mitochondrion integral to membrane, mitochondrial outer membrane translocase complex, mitochondrion protein transporter activity Human TOMM6 Reactome UniProtKB {GO:0006626=Reactome:REACT_118595, GO:0005741=GO_REF:0000039, GO:0044267=Reactome:REACT_17015} Q96B49 Mitochondrial import receptor subunit TOM6 homolog protein 20110427 {GO:0006626=TAS, GO:0005741=IEA, GO:0044267=TAS} cellular protein metabolic process, protein targeting to mitochondrion mitochondrial outer membrane Human TOMM7 BHF-UCL UniProtKB {GO:0005739=PMID:12198123, GO:0006626=PMID:15644312, GO:0005742=PMID:12198123, GO:0008320=PMID:15644312, GO:0016021=GO_REF:0000037, GO:0030150=GO_REF:0000002, GO:0044267=Reactome:REACT_17015} Q9P0U1 Mitochondrial import receptor subunit TOM7 homolog protein 20081105 {GO:0005739=IDA, GO:0006626=TAS, GO:0005742=IDA, GO:0008320=TAS, GO:0016021=IEA, GO:0030150=IEA, GO:0044267=TAS} cellular protein metabolic process, protein import into mitochondrial matrix, protein targeting to mitochondrion integral to membrane, mitochondrial outer membrane translocase complex, mitochondrion protein transmembrane transporter activity Human TOMM70A HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005515=PMID:12526792, GO:0006626=PMID:15644312, GO:0005742=PMID:15644312, GO:0008320=PMID:15644312, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015} O94826 Mitochondrial import receptor subunit TOM70 protein 20101115 {GO:0005739=IDA, GO:0005515=IPI, GO:0006626=TAS, GO:0005742=TAS, GO:0008320=TAS, GO:0016021=IEA, GO:0044267=TAS} cellular protein metabolic process, protein targeting to mitochondrion integral to membrane, mitochondrial outer membrane translocase complex, mitochondrion protein binding, protein transmembrane transporter activity Human TONSL HPA UniProtKB {GO:0005515=PMID:21055984, GO:0042555=PMID:21055984, GO:0035101=PMID:21055983, GO:0003714=PMID:7738005, GO:0005730=GO_REF:0000052, GO:0042994=PMID:7738005, GO:0005634=GO_REF:0000052, GO:0042393=PMID:21055984, GO:0005737=GO_REF:0000039, GO:0000724=PMID:21055984, GO:0031297=PMID:21055984, GO:0043596=PMID:21055984, GO:0005662=PMID:21055983} Q96HA7 Tonsoku-like protein protein 20111111 {GO:0005515=IPI, GO:0042555=IDA, GO:0035101=IDA, GO:0003714=TAS, GO:0005730=IDA, GO:0042994=TAS, GO:0005634=IDA, GO:0042393=IDA, GO:0005737=IEA, GO:0000724=IMP, GO:0031297=IMP, GO:0043596=IDA, GO:0005662=IDA} cytoplasmic sequestering of transcription factor, double-strand break repair via homologous recombination, replication fork processing DNA replication factor A complex, FACT complex, MCM complex, cytoplasm, nuclear replication fork, nucleolus, nucleus histone binding, protein binding, transcription corepressor activity NOT Human TOP1 HPA UniProtKB {GO:0005515=PMID:20195357, GO:0003917=PMID:14594810, GO:0003918=GO_REF:0000002, GO:0042493=PMID:16127745, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000228=PMID:9049244, GO:0012501=PMID:17172417, GO:0005524=GO_REF:0000037, GO:0003677=PMID:17355975, GO:0006260=GO_REF:0000033, GO:0016310=PMID:17481653, GO:0007059=GO_REF:0000033, GO:0000932=PMID:12878161, GO:0040016=GO_REF:0000019, GO:0003682=PMID:9049244, GO:0019048=GO_REF:0000037, GO:0043204=GO_REF:0000019, GO:0005654=PMID:9049244, GO:0006338=GO_REF:0000033, GO:0031298=GO_REF:0000033, GO:0006265=PMID:14594810} P11387 DNA topoisomerase 1 protein 20100326 {GO:0005515=IPI, GO:0003917=IDA, GO:0003918=IEA, GO:0042493=IEP, GO:0005730=IDA, GO:0005634=IDA, GO:0000228=IDA, GO:0012501=NAS, GO:0005524=IEA, GO:0003677=IDA, GO:0006260=IBA, GO:0016310=NAS, GO:0007059=IBA, GO:0000932=IDA, GO:0040016=IEA, GO:0003682=IDA, GO:0019048=IEA, GO:0043204=IEA, GO:0005654=IDA, GO:0006338=IBA, GO:0031298=IBA, GO:0006265=IDA} DNA replication, DNA topological change, chromatin remodeling, chromosome segregation, embryonic cleavage, phosphorylation, programmed cell death, response to drug, virus-host interaction cytoplasmic mRNA processing body, nuclear chromosome, nucleolus, nucleoplasm, nucleus, perikaryon, replication fork protection complex ATP binding, DNA binding, DNA topoisomerase type I activity, DNA topoisomerase type II (ATP-hydrolyzing) activity, chromatin binding, protein binding Human TOP1MT HPA UniProtKB {GO:0042645=PMID:18063578, GO:0006260=GO_REF:0000033, GO:0005739=GO_REF:0000052, GO:0003917=GO_REF:0000033, GO:0007059=GO_REF:0000033, GO:0003918=GO_REF:0000002, GO:0005694=GO_REF:0000002, GO:0005730=GO_REF:0000033, GO:0006338=GO_REF:0000033, GO:0031298=GO_REF:0000033, GO:0005524=GO_REF:0000037, GO:0006265=GO_REF:0000033} Q969P6 DNA topoisomerase I, mitochondrial protein 20080818 {GO:0042645=IDA, GO:0006260=IBA, GO:0005739=IDA, GO:0003917=IBA, GO:0007059=IBA, GO:0003918=IEA, GO:0005694=IEA, GO:0005730=IBA, GO:0006338=IBA, GO:0031298=IBA, GO:0005524=IEA, GO:0006265=IBA} DNA replication, DNA topological change, chromatin remodeling, chromosome segregation chromosome, mitochondrial nucleoid, mitochondrion, nucleolus, replication fork protection complex ATP binding, DNA topoisomerase type I activity, DNA topoisomerase type II (ATP-hydrolyzing) activity Human TOP2A HPA UniProtKB {GO:0005515=PMID:19390626, GO:0043130=PMID:15965487, GO:0000793=GO_REF:0000019, GO:0042826=PMID:11062478, GO:0000819=GO_REF:0000033, GO:0030261=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0042803=PMID:10473615, GO:0007059=PMID:15965487, GO:0040016=GO_REF:0000019, GO:0008144=PMID:16914642, GO:0019035=PMID:16712776, GO:0045944=GO_REF:0000019, GO:0005080=PMID:16611985, GO:0045070=PMID:16712776, GO:0008094=PMID:12079377, GO:0000287=PMID:22323612, GO:0043065=PMID:16611985, GO:0009330=PMID:10473615, GO:0000795=GO_REF:0000033, GO:0003918=PMID:16611985, GO:0046982=PMID:10473615, GO:0008301=PMID:22323612, GO:0005814=PMID:9049244, GO:0048015=PMID:15504738, GO:0005730=GO_REF:0000052, GO:0000228=PMID:9049244, GO:0006312=GO_REF:0000033, GO:0008022=PMID:10666337, GO:0005524=GO_REF:0000037, GO:0003677=PMID:10788521, GO:0006974=PMID:16611985, GO:0045870=PMID:16712776, GO:0006260=PMID:15504738, GO:0006261=GO_REF:0000033, GO:0043234=PMID:16611985, GO:0006281=PMID:15504738, GO:0000712=GO_REF:0000033, GO:0003682=PMID:9049244, GO:0030263=PMID:10959840, GO:0005654=Reactome:REACT_111167, GO:0000278=Reactome:REACT_152, GO:0019899=PMID:17567603, GO:0006265=PMID:22323612, GO:0006266=PMID:15491148, GO:0009295=GO_REF:0000033} P11388 DNA topoisomerase 2-alpha protein 20101115 {GO:0005515=IPI, GO:0043130=IMP, GO:0000793=IEA, GO:0042826=IPI, GO:0000819=IBA, GO:0030261=IEA, GO:0005634=IDA, GO:0042803=IPI, GO:0007059=IMP, GO:0040016=IEA, GO:0008144=IDA, GO:0019035=NAS, GO:0045944=IEA, GO:0005080=IPI, GO:0045070=IMP, GO:0008094=IDA, GO:0000287=IDA, GO:0043065=IDA, GO:0009330=IDA, GO:0000795=IBA, GO:0003918=IDA, GO:0046982=IPI, GO:0008301=IDA, GO:0005814=IDA, GO:0048015=NAS, GO:0005730=IDA, GO:0000228=IDA, GO:0006312=IBA, GO:0008022=IPI, GO:0005524=IEA, GO:0003677=IDA, GO:0006974=IDA, GO:0045870=IMP, GO:0006260=NAS, GO:0006261=IBA, GO:0043234=IPI, GO:0006281=NAS, GO:0000712=IBA, GO:0003682=IDA, GO:0030263=IDA, GO:0005654=TAS, GO:0000278=TAS, GO:0019899=IPI, GO:0006265=IDA, GO:0006266=IDA, GO:0009295=IBA} DNA ligation, DNA repair, DNA replication, DNA topological change, DNA-dependent DNA replication, apoptotic chromosome condensation, chromosome condensation, chromosome segregation, embryonic cleavage, mitotic cell cycle, mitotic recombination, phosphatidylinositol-mediated signaling, positive regulation of apoptotic process, positive regulation of retroviral genome replication, positive regulation of transcription from RNA polymerase II promoter, positive regulation of viral genome replication, resolution of meiotic recombination intermediates, response to DNA damage stimulus, sister chromatid segregation DNA topoisomerase complex (ATP-hydrolyzing), centriole, condensed chromosome, nuclear chromosome, nucleoid, nucleolus, nucleoplasm, nucleus, protein complex, synaptonemal complex, viral integration complex ATP binding, DNA binding, DNA binding, bending, DNA topoisomerase type II (ATP-hydrolyzing) activity, DNA-dependent ATPase activity, chromatin binding, drug binding, enzyme binding, histone deacetylase binding, magnesium ion binding, protein C-terminus binding, protein binding, protein heterodimerization activity, protein homodimerization activity, protein kinase C binding, ubiquitin binding Human TOP2B HPA UniProtKB {GO:0000792=PMID:9049244, GO:0042826=PMID:11062478, GO:0000819=GO_REF:0000033, GO:0005634=GO_REF:0000052, GO:0071778=PMID:12837248, GO:0007409=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=PMID:9049244, GO:0007059=GO_REF:0000033, GO:0005080=PMID:16611985, GO:0000795=GO_REF:0000033, GO:0003918=PMID:10684600, GO:0046982=PMID:10473615, GO:0005694=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0006312=GO_REF:0000033, GO:0008022=PMID:10666337, GO:0005524=GO_REF:0000037, GO:0006261=GO_REF:0000033, GO:0000712=GO_REF:0000033, GO:0003682=PMID:9049244, GO:0005654=PMID:9049244, GO:0030900=GO_REF:0000019, GO:0019899=PMID:17567603, GO:0001764=GO_REF:0000019, GO:0006265=PMID:10684600, GO:0009295=GO_REF:0000033} Q02880 DNA topoisomerase 2-beta protein 20101115 {GO:0000792=IDA, GO:0042826=IPI, GO:0000819=IBA, GO:0005634=IDA, GO:0071778=IDA, GO:0007409=IEA, GO:0046872=IEA, GO:0005829=IDA, GO:0007059=IBA, GO:0005080=IPI, GO:0000795=IBA, GO:0003918=IDA, GO:0046982=IPI, GO:0005694=IEA, GO:0005730=IDA, GO:0006312=IBA, GO:0008022=IPI, GO:0005524=IEA, GO:0006261=IBA, GO:0000712=IBA, GO:0003682=IDA, GO:0005654=IDA, GO:0030900=IEA, GO:0019899=IPI, GO:0001764=IEA, GO:0006265=IDA, GO:0009295=IBA} DNA topological change, DNA-dependent DNA replication, axonogenesis, chromosome segregation, forebrain development, mitotic recombination, neuron migration, resolution of meiotic recombination intermediates, sister chromatid segregation WINAC complex, chromosome, cytosol, heterochromatin, nucleoid, nucleolus, nucleoplasm, nucleus, synaptonemal complex ATP binding, DNA topoisomerase type II (ATP-hydrolyzing) activity, chromatin binding, enzyme binding, histone deacetylase binding, metal ion binding, protein C-terminus binding, protein heterodimerization activity, protein kinase C binding NOT Human TOP3A PINC UniProtKB {GO:0005515=PMID:10728666, GO:0003917=PMID:20445207, GO:0007126=PMID:8622991, GO:0005694=GO_REF:0000002, GO:0016605=PMID:10728666, GO:0005634=PMID:8622991, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=PMID:8622991, GO:0005524=GO_REF:0000037, GO:0006265=PMID:20445207} Q13472 DNA topoisomerase 3-alpha protein 20030904 {GO:0005515=IPI, GO:0003917=IDA, GO:0007126=TAS, GO:0005694=IEA, GO:0016605=IDA, GO:0005634=TAS, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=TAS, GO:0005524=IEA, GO:0006265=IDA} DNA topological change, meiosis PML body, chromosome, nucleus ATP binding, DNA binding, DNA topoisomerase type I activity, nucleic acid binding, protein binding, zinc ion binding Human TOP3B PINC UniProtKB {GO:0003916=PMID:9786843, GO:0000793=GO_REF:0000019, GO:0003917=GO_REF:0000003, GO:0007059=GO_REF:0000019, GO:0005694=GO_REF:0000002, GO:0005634=PMID:9786843, GO:0003677=PMID:9786843, GO:0005524=GO_REF:0000037, GO:0006265=GO_REF:0000002} O95985 DNA topoisomerase 3-beta-1 protein 20030904 {GO:0003916=TAS, GO:0000793=IEA, GO:0003917=IEA, GO:0007059=IEA, GO:0005694=IEA, GO:0005634=TAS, GO:0003677=TAS, GO:0005524=IEA, GO:0006265=IEA} DNA topological change, chromosome segregation chromosome, condensed chromosome, nucleus ATP binding, DNA binding, DNA topoisomerase activity, DNA topoisomerase type I activity Human TOPBP1 IntAct UniProtKB {GO:0005515=PMID:17887956, GO:0000794=GO_REF:0000019, GO:0005815=GO_REF:0000039, GO:0005694=PMID:21659603, GO:0005634=PMID:9461304, GO:0006259=PMID:9461304, GO:0008022=PMID:9461304, GO:0003677=GO_REF:0000037, GO:0006974=PMID:12773567, GO:0005737=GO_REF:0000037, GO:0000922=GO_REF:0000039, GO:0006281=PMID:12773567, GO:0010212=PMID:12773567, GO:0016605=PMID:12773567, GO:0001673=GO_REF:0000019} Q92547 DNA topoisomerase 2-binding protein 1 protein 20130415 {GO:0005515=IPI, GO:0000794=IEA, GO:0005815=IEA, GO:0005694=IDA, GO:0005634=TAS, GO:0006259=TAS, GO:0008022=TAS, GO:0003677=IEA, GO:0006974=IDA, GO:0005737=IEA, GO:0000922=IEA, GO:0006281=NAS, GO:0010212=IDA, GO:0016605=IDA, GO:0001673=IEA} DNA metabolic process, DNA repair, response to DNA damage stimulus, response to ionizing radiation PML body, chromosome, condensed nuclear chromosome, cytoplasm, male germ cell nucleus, microtubule organizing center, nucleus, spindle pole DNA binding, protein C-terminus binding, protein binding Human UniProtKB:O75419 TOPORS BHF-UCL UniProtKB {GO:0005515=PMID:20188669, GO:0006511=PMID:19473992, GO:0004842=PMID:15247280, GO:0034504=PMID:20188669, GO:0006513=PMID:15247280, GO:0005634=PMID:18077445, GO:0003823=PMID:10415337, GO:0036064=PMID:21159800, GO:0035845=PMID:21159800, GO:0042127=GO_REF:0000019, GO:0019789=PMID:19473992, GO:0051443=PMID:15247280, GO:0043066=PMID:21159800, GO:0046549=PMID:21159800, GO:0008630=PMID:20188669, GO:0016925=PMID:20188669, GO:0046548=PMID:21159800, GO:0010842=PMID:21159800, GO:0003677=PMID:11278651, GO:0006974=PMID:15735665, GO:0006351=PMID:10352183, GO:0044547=PMID:10352183, GO:0016607=PMID:14516784, GO:0051457=PMID:14516784, GO:0016605=PMID:20188669, GO:0032391=PMID:21159800, GO:0043161=PMID:18077445, GO:0008270=GO_REF:0000002, GO:0005868=PMID:21159800, GO:0045893=GO_REF:0000019, GO:0070936=PMID:15247280} Q9NS56 E3 ubiquitin-protein ligase Topors protein 20120530 {GO:0005515=IPI, GO:0006511=IMP, GO:0004842=IDA, GO:0034504=IMP, GO:0006513=IDA, GO:0005634=IDA, GO:0003823=IPI, GO:0036064=IDA, GO:0035845=ISS, GO:0042127=IEA, GO:0019789=IMP, GO:0051443=IDA, GO:0043066=ISS, GO:0046549=ISS, GO:0008630=IDA, GO:0016925=IMP, GO:0046548=ISS, GO:0010842=ISS, GO:0003677=IDA, GO:0006974=IDA, GO:0006351=NAS, GO:0044547=IPI, GO:0016607=IDA, GO:0051457=IDA, GO:0016605=IDA, GO:0032391=IDA, GO:0043161=IMP, GO:0008270=IEA, GO:0005868=TAS, GO:0045893=IEA, GO:0070936=IDA} intrinsic apoptotic signaling pathway in response to DNA damage, maintenance of protein location in nucleus, negative regulation of apoptotic process, photoreceptor cell outer segment organization, positive regulation of transcription, DNA-dependent, positive regulation of ubiquitin-protein ligase activity, proteasomal ubiquitin-dependent protein catabolic process, protein K48-linked ubiquitination, protein localization to nucleus, protein monoubiquitination, protein sumoylation, regulation of cell proliferation, response to DNA damage stimulus, retina layer formation, retinal cone cell development, retinal rod cell development, transcription, DNA-dependent, ubiquitin-dependent protein catabolic process PML body, cilium basal body, cytoplasmic dynein complex, nuclear speck, nucleus, photoreceptor connecting cilium DNA binding, DNA topoisomerase binding, SUMO ligase activity, antigen binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q5BLE0 TOR1A MGI UniProtKB {GO:0006986=PMID:9288096, GO:0005737=PMID:10814722, GO:0031965=GO_REF:0000039, GO:0004252=PMID:9288096, GO:0006457=PMID:9288096, GO:0005783=PMID:10814722, GO:0051085=GO_REF:0000002, GO:0005788=PMID:20015956, GO:0051260=PMID:20015956, GO:0051082=PMID:10814722, GO:0071763=GO_REF:0000019, GO:0005524=GO_REF:0000037} O14656 Torsin-1A protein 20120405 {GO:0006986=TAS, GO:0005737=TAS, GO:0031965=IEA, GO:0004252=TAS, GO:0006457=TAS, GO:0005783=TAS, GO:0051085=IEA, GO:0005788=IDA, GO:0051260=IDA, GO:0051082=TAS, GO:0071763=IEA, GO:0005524=IEA} chaperone mediated protein folding requiring cofactor, nuclear membrane organization, protein folding, protein homooligomerization, response to unfolded protein cytoplasm, endoplasmic reticulum, endoplasmic reticulum lumen, nuclear membrane ATP binding, serine-type endopeptidase activity, unfolded protein binding Human TOR1AIP1 UniProtKB UniProtKB {GO:0034504=GO_REF:0000019, GO:0005637=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0071763=GO_REF:0000019, GO:0005521=GO_REF:0000019} Q5JTV8 Torsin-1A-interacting protein 1 protein 20130413 {GO:0034504=IEA, GO:0005637=IEA, GO:0016021=IEA, GO:0071763=IEA, GO:0005521=IEA} nuclear membrane organization, protein localization to nucleus integral to membrane, nuclear inner membrane lamin binding Human UniProtKB-SubCell:SL-0179 TOR1AIP2 UniProtKB UniProtKB {GO:0031965=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q8NFQ8 Torsin-1A-interacting protein 2 protein 20130413 {GO:0031965=IEA, GO:0005789=IEA, GO:0016021=IEA} endoplasmic reticulum membrane, integral to membrane, nuclear membrane Human UniProtKB-SubCell:SL-0182 TOR1B MGI UniProtKB {GO:0006986=PMID:10644435, GO:0017111=GO_REF:0000002, GO:0051085=GO_REF:0000002, GO:0005788=PMID:20015956, GO:0051260=PMID:20015956, GO:0051082=PMID:9288096, GO:0005635=GO_REF:0000019, GO:0071763=GO_REF:0000019, GO:0005524=GO_REF:0000037} O14657 Torsin-1B protein 20120406 {GO:0006986=TAS, GO:0017111=IEA, GO:0051085=IEA, GO:0005788=IDA, GO:0051260=IDA, GO:0051082=TAS, GO:0005635=IEA, GO:0071763=IEA, GO:0005524=IEA} chaperone mediated protein folding requiring cofactor, nuclear membrane organization, protein homooligomerization, response to unfolded protein endoplasmic reticulum lumen, nuclear envelope ATP binding, nucleoside-triphosphatase activity, unfolded protein binding Human TOR3A MGI UniProtKB {GO:0051085=GO_REF:0000002, GO:0005788=PMID:20015956, GO:0005524=GO_REF:0000037} Q9H497 Torsin-3A protein 20120406 {GO:0051085=IEA, GO:0005788=IDA, GO:0005524=IEA} chaperone mediated protein folding requiring cofactor endoplasmic reticulum lumen ATP binding Human TOX2 UniProtKB UniProtKB {GO:0008585=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0045944=GO_REF:0000019, GO:0001085=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0034698=GO_REF:0000019} Q96NM4 TOX high mobility group box family member 2 protein 20130413 {GO:0008585=IEA, GO:0006355=IEA, GO:0045944=IEA, GO:0001085=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0034698=IEA} female gonad development, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, response to gonadotropin stimulus, transcription, DNA-dependent nucleus DNA binding, RNA polymerase II transcription factor binding Human UniProtKB-SubCell:SL-0191 TOX3 UniProtKB UniProtKB {GO:0034056=PMID:21172805, GO:0005515=PMID:21172805, GO:0051219=PMID:21172805, GO:0043524=PMID:21172805, GO:0003682=PMID:21172805, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0045893=PMID:21172805, GO:0042803=PMID:21172805, GO:0006351=GO_REF:0000037} O15405 TOX high mobility group box family member 3 protein 20110406 {GO:0034056=IDA, GO:0005515=IPI, GO:0051219=IPI, GO:0043524=IDA, GO:0003682=IDA, GO:0006915=IEA, GO:0005634=IEA, GO:0045893=IDA, GO:0042803=IDA, GO:0006351=IEA} apoptotic process, negative regulation of neuron apoptotic process, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus chromatin binding, estrogen response element binding, phosphoprotein binding, protein binding, protein homodimerization activity Human TOX4 HPA UniProtKB {GO:0005515=PMID:20516061, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0072357=PMID:20516061, GO:0000785=PMID:20516061, GO:0003677=GO_REF:0000037} O94842 TOX high mobility group box family member 4 protein 20101115 {GO:0005515=IPI, GO:0005730=IDA, GO:0005634=IDA, GO:0072357=IDA, GO:0000785=IDA, GO:0003677=IEA} PTW/PP1 phosphatase complex, chromatin, nucleolus, nucleus DNA binding, protein binding NOT Human TP53 BHF-UCL UniProtKB {GO:0005515=PMID:17805299, GO:0030308=PMID:8986812, GO:0009651=GO_REF:0000019, GO:0003700=PMID:18549481, GO:0044212=PMID:15710329, GO:0009303=GO_REF:0000019, GO:0050731=PMID:19749791, GO:0051402=GO_REF:0000019, GO:0030154=PMID:10065150, GO:0034644=GO_REF:0000033, GO:0002326=GO_REF:0000019, GO:0010332=PMID:7958916, GO:0046677=PMID:20810912, GO:0031625=PMID:9529249, GO:0000060=GO_REF:0000019, GO:0035035=PMID:10518217, GO:0035033=GO_REF:0000019, GO:0046982=PMID:10837489, GO:0005507=PMID:7824276, GO:0070245=GO_REF:0000024, GO:0007275=PMID:10065150, GO:0001701=GO_REF:0000019, GO:0071479=PMID:20160708, GO:0042771=PMID:14744935, GO:0000733=PMID:8183576, GO:0006284=PMID:15116721, GO:0000075=Reactome:REACT_1538, GO:0008270=PMID:10065153, GO:0006289=PMID:7663514, GO:0090399=PMID:19951988, GO:0008134=PMID:15705871, GO:0005783=GO_REF:0000039, GO:0048147=PMID:10962037, GO:0051087=PMID:18086682, GO:0001836=GO_REF:0000019, GO:0005634=PMID:18756595, GO:0090343=GO_REF:0000019, GO:0008340=GO_REF:0000024, GO:0046872=GO_REF:0000038, GO:0016363=PMID:11080164, GO:0005829=PMID:14963330, GO:0006302=GO_REF:0000019, GO:0002309=GO_REF:0000019, GO:0051721=PMID:17245430, GO:0030971=PMID:23027130, GO:0046902=PMID:15116721, GO:0042493=GO_REF:0000019, GO:0071456=PMID:20810912, GO:0042981=PMID:14744935, GO:0051097=PMID:7663514, GO:0035690=PMID:20810912, GO:0006974=PMID:15710329, GO:0071850=GO_REF:0000019, GO:0031065=GO_REF:0000033, GO:0007596=Reactome:REACT_604, GO:0031571=PMID:7958916, GO:0008156=GO_REF:0000019, GO:0000790=PMID:22521434, GO:0006983=PMID:14744935, GO:0005657=GO_REF:0000033, GO:0001756=GO_REF:0000019, GO:0002020=PMID:11923872, GO:0071158=PMID:21471221, GO:0007406=GO_REF:0000019, GO:0042802=PMID:21988832, GO:0043525=GO_REF:0000033, GO:0005759=GO_REF:0000039, GO:0002360=GO_REF:0000019, GO:0007179=GO_REF:0000019, GO:0006978=PMID:7958916, GO:0006979=GO_REF:0000019, GO:0000785=GO_REF:0000033, GO:0006977=Reactome:REACT_1625, GO:0033077=GO_REF:0000019, GO:0030330=PMID:20160708, GO:0019901=PMID:21317932, GO:0007569=PMID:12080348, GO:0000122=PMID:19749791, GO:0007417=GO_REF:0000019, GO:0043234=PMID:9529249, GO:0007049=GO_REF:0000038, GO:0072332=PMID:12172011, GO:0005654=Reactome:REACT_25186, GO:0019899=PMID:17805299, GO:0045893=PMID:18549481, GO:0045892=PMID:19749791, GO:2000379=PMID:20160708, GO:0051276=GO_REF:0000019, GO:0008285=GO_REF:0000024, GO:0007369=GO_REF:0000019, GO:0010165=GO_REF:0000033, GO:0008283=PMID:10065150, GO:0090403=PMID:19951988, GO:0007265=PMID:9054499, GO:0005739=PMID:12667443, GO:0002039=GO_REF:0000033, GO:0097371=GO_REF:0000019, GO:0005737=PMID:14744935, GO:0008104=PMID:16507995, GO:0035264=GO_REF:0000019, GO:0045944=PMID:11672523, GO:0001085=PMID:18549481, GO:0007050=PMID:7958916, GO:0042149=PMID:14744935, GO:0030512=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0006355=PMID:7587074, GO:0043065=PMID:20959462, GO:0005669=PMID:15053879, GO:0051262=PMID:15116721, GO:0005730=PMID:12080348, GO:0006915=PMID:16322561, GO:0006917=GO_REF:0000019, GO:0003677=PMID:2144364, GO:0005524=PMID:8183576, GO:0097193=PMID:16462759, GO:0006351=GO_REF:0000038, GO:0003684=GO_REF:0000033, GO:0016604=PMID:10360174, GO:0001077=GO_REF:0000019, GO:0047485=PMID:11861836, GO:0006461=PMID:12915590, GO:0003682=PMID:17599062, GO:0019048=GO_REF:0000037, GO:0016605=PMID:12006491} P04637 Cellular tumor antigen p53 protein 20101001 {GO:0005515=IPI, GO:0030308=IMP, GO:0009651=IEA, GO:0003700=IDA, GO:0044212=IDA, GO:0009303=IEA, GO:0050731=ISS, GO:0051402=IEA, GO:0030154=TAS, GO:0034644=IBA, GO:0002326=IEA, GO:0010332=IMP, GO:0046677=IEP, GO:0031625=IPI, GO:0000060=IEA, GO:0035035=IPI, GO:0035033=IEA, GO:0046982=IPI, GO:0005507=IDA, GO:0070245=ISS, GO:0007275=IMP, GO:0001701=IEA, GO:0071479=IMP, GO:0042771=IDA, GO:0000733=IDA, GO:0006284=TAS, GO:0000075=TAS, GO:0008270=TAS, GO:0006289=IMP, GO:0090399=IMP, GO:0008134=IPI, GO:0005783=IEA, GO:0048147=IMP, GO:0051087=IPI, GO:0001836=IEA, GO:0005634=IDA, GO:0090343=IEA, GO:0008340=ISS, GO:0046872=IEA, GO:0016363=IDA, GO:0005829=IDA, GO:0006302=IEA, GO:0002309=IEA, GO:0051721=IPI, GO:0030971=IPI, GO:0046902=TAS, GO:0042493=IEA, GO:0071456=IEP, GO:0042981=IDA, GO:0051097=TAS, GO:0035690=IEP, GO:0006974=IDA, GO:0071850=IEA, GO:0031065=IBA, GO:0007596=TAS, GO:0031571=IMP, GO:0008156=IEA, GO:0000790=IDA, GO:0006983=IDA, GO:0005657=IBA, GO:0001756=IEA, GO:0002020=IPI, GO:0071158=IMP, GO:0007406=IEA, GO:0042802=IPI, GO:0043525=IBA, GO:0005759=IEA, GO:0002360=IEA, GO:0007179=IEA, GO:0006978=IMP, GO:0006979=IEA, GO:0000785=IBA, GO:0006977=TAS, GO:0033077=IEA, GO:0030330=IMP, GO:0019901=IPI, GO:0007569=IMP, GO:0000122=ISS, GO:0007417=IEA, GO:0043234=IDA, GO:0007049=IEA, GO:0072332=IMP, GO:0005654=TAS, GO:0019899=IPI, GO:0045893=IDA, GO:0045892=ISS, GO:2000379=IMP, GO:0051276=IEA, GO:0008285=ISS, GO:0007369=IEA, GO:0010165=IBA, GO:0008283=TAS, GO:0090403=IMP, GO:0007265=IEP, GO:0005739=IDA, GO:0002039=IBA, GO:0097371=IEA, GO:0005737=IDA, GO:0008104=IDA, GO:0035264=IEA, GO:0045944=IDA, GO:0001085=IPI, GO:0007050=IMP, GO:0042149=IDA, GO:0030512=IEA, GO:0043066=IEA, GO:0006355=IDA, GO:0043065=IDA, GO:0005669=IDA, GO:0051262=TAS, GO:0005730=IDA, GO:0006915=IMP, GO:0006917=IEA, GO:0003677=IMP, GO:0005524=IDA, GO:0097193=TAS, GO:0006351=IEA, GO:0003684=IBA, GO:0016604=IDA, GO:0001077=IEA, GO:0047485=IPI, GO:0006461=IDA, GO:0003682=IDA, GO:0019048=IEA, GO:0016605=IDA} B cell lineage commitment, DNA damage response, signal transduction by p53 class mediator, DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, DNA strand renaturation, ER overload response, Ras protein signal transduction, T cell differentiation in thymus, T cell lineage commitment, T cell proliferation involved in immune response, apoptotic process, base-excision repair, blood coagulation, cell aging, cell cycle, cell cycle arrest, cell cycle checkpoint, cell differentiation, cell proliferation, cellular response to UV, cellular response to drug, cellular response to glucose starvation, cellular response to hypoxia, cellular response to ionizing radiation, central nervous system development, chromosome organization, determination of adult lifespan, double-strand break repair, gastrulation, in utero embryonic development, induction of apoptosis, intrinsic apoptotic signaling pathway, intrinsic apoptotic signaling pathway by p53 class mediator, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, mitotic G1 DNA damage checkpoint, mitotic cell cycle arrest, multicellular organism growth, multicellular organismal development, negative regulation of DNA replication, negative regulation of apoptotic process, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of fibroblast proliferation, negative regulation of helicase activity, negative regulation of neuroblast proliferation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, negative regulation of transforming growth factor beta receptor signaling pathway, neuron apoptotic process, nucleotide-excision repair, oxidative stress-induced premature senescence, positive regulation of apoptotic process, positive regulation of cell aging, positive regulation of cell cycle arrest, positive regulation of histone deacetylation, positive regulation of neuron apoptotic process, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of reactive oxygen species metabolic process, positive regulation of thymocyte apoptotic process, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, protein complex assembly, protein import into nucleus, translocation, protein localization, protein tetramerization, rRNA transcription, regulation of apoptotic process, regulation of mitochondrial membrane permeability, regulation of transcription, DNA-dependent, release of cytochrome c from mitochondria, replicative senescence, response to DNA damage stimulus, response to X-ray, response to antibiotic, response to drug, response to gamma radiation, response to oxidative stress, response to salt stress, somitogenesis, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, virus-host interaction PML body, chromatin, cytoplasm, cytosol, endoplasmic reticulum, mitochondrial matrix, mitochondrion, nuclear body, nuclear chromatin, nuclear matrix, nucleolus, nucleoplasm, nucleus, protein complex, replication fork, transcription factor TFIID complex ATP binding, DNA binding, MDM2/MDM4 family protein binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II transcription factor binding, chaperone binding, chromatin binding, copper ion binding, damaged DNA binding, enzyme binding, histone acetyltransferase binding, histone deacetylase regulator activity, identical protein binding, metal ion binding, p53 binding, protease binding, protein N-terminus binding, protein binding, protein heterodimerization activity, protein kinase binding, protein phosphatase 2A binding, receptor tyrosine kinase binding, sequence-specific DNA binding transcription factor activity, transcription factor binding, transcription regulatory region DNA binding, ubiquitin protein ligase binding, zinc ion binding Human UniProtKB:P02340 TP53AIP1 UniProtKB UniProtKB {GO:0005739=PMID:11030628, GO:0003674=GO_REF:0000015, GO:0006915=PMID:11030628} Q9HCN2 p53-regulated apoptosis-inducing protein 1 protein 20010807 {GO:0005739=TAS, GO:0003674=ND, GO:0006915=TAS} apoptotic process mitochondrion molecular_function Human TP53BP1 HPA UniProtKB {GO:0005515=PMID:22621922, GO:0001102=PMID:17805299, GO:0000781=PMID:15149599, GO:0001104=PMID:17805299, GO:0005657=GO_REF:0000019, GO:0042162=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0035064=PMID:22373579, GO:0006974=PMID:17500065, GO:0006302=Reactome:REACT_2054, GO:0003684=GO_REF:0000019, GO:0002039=PMID:17805299, GO:0051091=PMID:17805299, GO:0005737=PMID:9748285, GO:0006281=Reactome:REACT_216, GO:0000724=Reactome:REACT_1874, GO:0045944=PMID:17805299, GO:0000777=GO_REF:0000039, GO:0005654=Reactome:REACT_1508, GO:0045893=PMID:9748285} Q12888 Tumor suppressor p53-binding protein 1 protein 20101115 {GO:0005515=IPI, GO:0001102=IPI, GO:0000781=IDA, GO:0001104=IMP, GO:0005657=IEA, GO:0042162=IEA, GO:0005634=IDA, GO:0035064=IDA, GO:0006974=IDA, GO:0006302=TAS, GO:0003684=IEA, GO:0002039=IPI, GO:0051091=IC, GO:0005737=IDA, GO:0006281=TAS, GO:0000724=TAS, GO:0045944=IMP, GO:0000777=IEA, GO:0005654=TAS, GO:0045893=NAS} DNA repair, double-strand break repair, double-strand break repair via homologous recombination, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, response to DNA damage stimulus chromosome, telomeric region, condensed chromosome kinetochore, cytoplasm, nucleoplasm, nucleus, replication fork RNA polymerase II activating transcription factor binding, RNA polymerase II transcription cofactor activity, damaged DNA binding, methylated histone residue binding, p53 binding, protein binding, telomeric DNA binding Human TP53BP2 BHF-UCL UniProtKB {GO:0005515=PMID:10646860, GO:0048471=PMID:10646860, GO:0017124=GO_REF:0000037, GO:0051059=PMID:10498867, GO:0006915=GO_REF:0000037, GO:0005634=PMID:19377511, GO:0006917=PMID:11684014, GO:0007417=GO_REF:0000019, GO:0045786=PMID:14729977, GO:0009792=GO_REF:0000019, GO:0007507=GO_REF:0000019, GO:0007165=PMID:9748285, GO:0007049=GO_REF:0000037, GO:0005737=PMID:10646860, GO:0005070=PMID:8668206, GO:0010212=GO_REF:0000019} Q13625 Apoptosis-stimulating of p53 protein 2 protein 20101014 {GO:0005515=IPI, GO:0048471=IDA, GO:0017124=IEA, GO:0051059=IPI, GO:0006915=IEA, GO:0005634=IDA, GO:0006917=IDA, GO:0007417=IEA, GO:0045786=TAS, GO:0009792=IEA, GO:0007507=IEA, GO:0007165=TAS, GO:0007049=IEA, GO:0005737=IDA, GO:0005070=TAS, GO:0010212=IEA} apoptotic process, cell cycle, central nervous system development, embryo development ending in birth or egg hatching, heart development, induction of apoptosis, negative regulation of cell cycle, response to ionizing radiation, signal transduction cytoplasm, nucleus, perinuclear region of cytoplasm NF-kappaB binding, SH3 domain binding, SH3/SH2 adaptor activity, protein binding colocalizes_with Human TP53I11 PINC UniProtKB {GO:0008285=PMID:9305847, GO:0006950=PMID:9305847, GO:0016021=GO_REF:0000037} O14683 Tumor protein p53-inducible protein 11 protein 20030904 {GO:0008285=TAS, GO:0006950=TAS, GO:0016021=IEA} negative regulation of cell proliferation, response to stress integral to membrane Human TP53I3 UniProtKB UniProtKB {GO:0048038=PMID:19349281, GO:0008631=GO_REF:0000029, GO:0016491=GO_REF:0000002, GO:0006739=PMID:19349281, GO:0008270=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0003960=PMID:19349281, GO:0070402=PMID:19349281, GO:0042803=PMID:19349281} Q53FA7 Quinone oxidoreductase PIG3 protein 20090904 {GO:0048038=IDA, GO:0008631=NAS, GO:0016491=IEA, GO:0006739=IDA, GO:0008270=IEA, GO:0005575=ND, GO:0003960=IDA, GO:0070402=IDA, GO:0042803=IPI} NADP metabolic process, intrinsic apoptotic signaling pathway in response to oxidative stress cellular_component NADPH binding, NADPH:quinone reductase activity, oxidoreductase activity, protein homodimerization activity, quinone binding, zinc ion binding Human UniProtKB:Q53FA7 TP53INP1 UniProtKB UniProtKB {GO:0005515=PMID:22470510, GO:0048102=PMID:22421968, GO:0030336=GO_REF:0000024, GO:0008285=GO_REF:0000024, GO:0016209=GO_REF:0000024, GO:0005776=PMID:22470510, GO:0006950=PMID:22421968, GO:0006914=GO_REF:0000037, GO:0006915=GO_REF:0000019, GO:0005634=PMID:22470510, GO:0031410=GO_REF:0000037, GO:0006917=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0005829=PMID:22470510, GO:0016605=GO_REF:0000039, GO:0007050=PMID:22421968, GO:0045893=PMID:22470510, GO:0010508=PMID:22470510} Q96A56 Tumor protein p53-inducible nuclear protein 1 protein 20120424 {GO:0005515=IPI, GO:0048102=IMP, GO:0030336=ISS, GO:0008285=ISS, GO:0016209=ISS, GO:0005776=IDA, GO:0006950=TAS, GO:0006914=IEA, GO:0006915=IEA, GO:0005634=IDA, GO:0031410=IEA, GO:0006917=IEA, GO:0006351=IEA, GO:0005829=IDA, GO:0016605=IEA, GO:0007050=TAS, GO:0045893=IDA, GO:0010508=IMP} apoptotic process, autophagic cell death, autophagy, cell cycle arrest, induction of apoptosis, negative regulation of cell migration, negative regulation of cell proliferation, positive regulation of autophagy, positive regulation of transcription, DNA-dependent, response to stress, transcription, DNA-dependent PML body, autophagic vacuole, cytoplasmic vesicle, cytosol, nucleus antioxidant activity, protein binding Human UniProtKB:Q9BXW4 TP53RK IntAct UniProtKB {GO:0005515=PMID:23455922, GO:0002039=PMID:11546806, GO:0016020=GO_REF:0000002, GO:0004674=PMID:11546806, GO:0005634=PMID:11546806, GO:0006468=PMID:11546806, GO:0004713=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0009103=GO_REF:0000002} Q96S44 TP53-regulating kinase protein 20130415 {GO:0005515=IPI, GO:0002039=IDA, GO:0016020=IEA, GO:0004674=IDA, GO:0005634=IDA, GO:0006468=IDA, GO:0004713=IEA, GO:0005524=IEA, GO:0009103=IEA} lipopolysaccharide biosynthetic process, protein phosphorylation membrane, nucleus ATP binding, p53 binding, protein binding, protein serine/threonine kinase activity, protein tyrosine kinase activity Human UniProtKB:Q9Y3C4 TP53TG3 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039} Q9ULZ0 TP53-target gene 3 protein protein 20130413 {GO:0005737=IEA, GO:0005634=IEA} cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 TP53TG5 UniProtKB UniProtKB {GO:0035556=PMID:10719363, GO:0003674=GO_REF:0000015, GO:0030308=PMID:10719363, GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039} Q9Y2B4 TP53-target gene 5 protein protein 20061026 {GO:0035556=NAS, GO:0003674=ND, GO:0030308=NAS, GO:0005737=IEA, GO:0005634=IEA} intracellular signal transduction, negative regulation of cell growth cytoplasm, nucleus molecular_function Human TP63 HPA UniProtKB {GO:0005515=PMID:21988832, GO:0000790=PMID:22521434, GO:0003700=GO_REF:0000033, GO:0044212=GO_REF:0000002, GO:0051402=GO_REF:0000019, GO:0042802=PMID:12446779, GO:0031069=GO_REF:0000019, GO:0045617=GO_REF:0000019, GO:0043523=GO_REF:0000033, GO:0034644=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0007219=GO_REF:0000037, GO:0048745=GO_REF:0000019, GO:0002064=GO_REF:0000019, GO:0048807=GO_REF:0000019, GO:0006978=GO_REF:0000033, GO:0000785=GO_REF:0000033, GO:0010332=GO_REF:0000033, GO:0045747=PMID:11641404, GO:0005794=GO_REF:0000052, GO:0007569=GO_REF:0000019, GO:0000122=GO_REF:0000033, GO:0048485=GO_REF:0000019, GO:0042771=GO_REF:0000033, GO:0001501=GO_REF:0000019, GO:0043589=GO_REF:0000019, GO:0045893=PMID:16343436, GO:0045892=PMID:12446784, GO:0001736=GO_REF:0000019, GO:0060529=GO_REF:0000019, GO:0010165=GO_REF:0000033, GO:0010259=GO_REF:0000019, GO:0009954=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0030326=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0030425=GO_REF:0000033, GO:0005829=GO_REF:0000033, GO:0002039=GO_REF:0000033, GO:0005737=PMID:10657951, GO:0030859=GO_REF:0000019, GO:0051289=PMID:10373484, GO:0045944=PMID:22521434, GO:0042475=GO_REF:0000019, GO:0006338=GO_REF:0000019, GO:0005667=GO_REF:0000033, GO:0043066=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0006915=PMID:9774969, GO:0002053=GO_REF:0000019, GO:0006917=GO_REF:0000019, GO:0003677=PMID:9662346, GO:0043616=GO_REF:0000019, GO:0036342=GO_REF:0000019, GO:0045669=PMID:22521434, GO:0043565=GO_REF:0000033, GO:0003684=GO_REF:0000033, GO:0001077=GO_REF:0000019, GO:0030216=GO_REF:0000019, GO:0060197=GO_REF:0000019, GO:0003682=GO_REF:0000033, GO:0060157=GO_REF:0000019, GO:0060513=GO_REF:0000019, GO:0007499=GO_REF:0000019, GO:0031571=GO_REF:0000033} Q9H3D4 Tumor protein 63 protein 20101115 {GO:0005515=IPI, GO:0000790=IDA, GO:0003700=IBA, GO:0044212=IEA, GO:0051402=IEA, GO:0042802=IPI, GO:0031069=IEA, GO:0045617=IEA, GO:0043523=IBA, GO:0034644=IBA, GO:0003690=IBA, GO:0007219=IEA, GO:0048745=IEA, GO:0002064=IEA, GO:0048807=IEA, GO:0006978=IBA, GO:0000785=IBA, GO:0010332=IBA, GO:0045747=IDA, GO:0005794=IDA, GO:0007569=IEA, GO:0000122=IBA, GO:0048485=IEA, GO:0042771=IBA, GO:0001501=IEA, GO:0043589=IEA, GO:0045893=IDA, GO:0045892=IDA, GO:0001736=IEA, GO:0060529=IEA, GO:0010165=IBA, GO:0010259=IEA, GO:0009954=IEA, GO:0005634=IDA, GO:0030326=IEA, GO:0046872=IEA, GO:0030425=IBA, GO:0005829=IBA, GO:0002039=IBA, GO:0005737=IDA, GO:0030859=IEA, GO:0051289=IPI, GO:0045944=IDA, GO:0042475=IEA, GO:0006338=IEA, GO:0005667=IBA, GO:0043066=IEA, GO:0005730=IDA, GO:0006915=IDA, GO:0002053=IEA, GO:0006917=IEA, GO:0003677=NAS, GO:0043616=IEA, GO:0036342=IEA, GO:0045669=IMP, GO:0043565=IBA, GO:0003684=IBA, GO:0001077=IEA, GO:0030216=IEA, GO:0060197=IEA, GO:0003682=IBA, GO:0060157=IEA, GO:0060513=IEA, GO:0007499=IEA, GO:0031571=IBA} DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, Notch signaling pathway, apoptotic process, cell aging, cellular response to UV, chromatin remodeling, cloacal septation, ectoderm and mesoderm interaction, embryonic limb morphogenesis, epithelial cell development, establishment of planar polarity, female genitalia morphogenesis, hair follicle morphogenesis, induction of apoptosis, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, keratinocyte differentiation, keratinocyte proliferation, mitotic G1 DNA damage checkpoint, multicellular organismal aging, negative regulation of apoptotic process, negative regulation of keratinocyte differentiation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, neuron apoptotic process, odontogenesis of dentin-containing tooth, polarized epithelial cell differentiation, positive regulation of Notch signaling pathway, positive regulation of mesenchymal cell proliferation, positive regulation of osteoblast differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, post-anal tail morphogenesis, prostatic bud formation, protein homotetramerization, proximal/distal pattern formation, regulation of neuron apoptotic process, response to X-ray, response to gamma radiation, skeletal system development, skin morphogenesis, smooth muscle tissue development, squamous basal epithelial stem cell differentiation involved in prostate gland acinus development, sympathetic nervous system development, urinary bladder development Golgi apparatus, chromatin, cytoplasm, cytosol, dendrite, nuclear chromatin, nucleolus, nucleus, transcription factor complex DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, chromatin binding, damaged DNA binding, double-stranded DNA binding, identical protein binding, metal ion binding, p53 binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding Human TP73 IntAct UniProtKB {GO:0005515=PMID:22340593, GO:0003700=PMID:15678106, GO:0010165=GO_REF:0000033, GO:0044212=PMID:16343436, GO:0001836=GO_REF:0000019, GO:0005634=PMID:19490146, GO:0009791=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0042802=PMID:22340593, GO:0005829=GO_REF:0000033, GO:0002039=GO_REF:0000033, GO:0000187=GO_REF:0000019, GO:0043524=GO_REF:0000033, GO:0034644=GO_REF:0000033, GO:0003690=GO_REF:0000033, GO:0006954=GO_REF:0000019, GO:0048666=GO_REF:0000019, GO:0045944=PMID:18174154, GO:0007050=GO_REF:0000019, GO:0006298=PMID:10391249, GO:0043508=GO_REF:0000033, GO:0006978=GO_REF:0000033, GO:0010332=GO_REF:0000033, GO:0000785=GO_REF:0000033, GO:0005667=GO_REF:0000033, GO:0051262=GO_REF:0000002, GO:0043065=GO_REF:0000019, GO:0008630=PMID:10391251, GO:0019901=PMID:18174154, GO:0001822=GO_REF:0000019, GO:0006915=GO_REF:0000002, GO:0010243=GO_REF:0000019, GO:0000122=GO_REF:0000033, GO:0048546=GO_REF:0000019, GO:0006974=PMID:18174154, GO:0006351=GO_REF:0000037, GO:0003684=GO_REF:0000033, GO:0043565=GO_REF:0000019, GO:0042771=PMID:18174154, GO:0021766=GO_REF:0000019, GO:0045793=GO_REF:0000019, GO:0045665=GO_REF:0000019, GO:0003682=GO_REF:0000033, GO:0048714=GO_REF:0000019, GO:0033326=GO_REF:0000019, GO:0031571=GO_REF:0000033, GO:0045893=PMID:15678106} O15350 Tumor protein p73 protein 20130415 {GO:0005515=IPI, GO:0003700=IDA, GO:0010165=IBA, GO:0044212=IDA, GO:0001836=IEA, GO:0005634=IDA, GO:0009791=IEA, GO:0046872=IEA, GO:0042802=IPI, GO:0005829=IBA, GO:0002039=IBA, GO:0000187=IEA, GO:0043524=IBA, GO:0034644=IBA, GO:0003690=IBA, GO:0006954=IEA, GO:0048666=IEA, GO:0045944=IDA, GO:0007050=IEA, GO:0006298=TAS, GO:0043508=IBA, GO:0006978=IBA, GO:0010332=IBA, GO:0000785=IBA, GO:0005667=IBA, GO:0051262=IEA, GO:0043065=IEA, GO:0008630=TAS, GO:0019901=IPI, GO:0001822=IEA, GO:0006915=IEA, GO:0010243=IEA, GO:0000122=IBA, GO:0048546=IEA, GO:0006974=IDA, GO:0006351=IEA, GO:0003684=IBA, GO:0043565=IEA, GO:0042771=IDA, GO:0021766=IEA, GO:0045793=IEA, GO:0045665=IEA, GO:0003682=IBA, GO:0048714=IEA, GO:0033326=IEA, GO:0031571=IBA, GO:0045893=IDA} DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, activation of MAPK activity, apoptotic process, cell cycle arrest, cellular response to UV, cerebrospinal fluid secretion, digestive tract morphogenesis, hippocampus development, inflammatory response, intrinsic apoptotic signaling pathway in response to DNA damage, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, kidney development, mismatch repair, mitotic G1 DNA damage checkpoint, negative regulation of JUN kinase activity, negative regulation of neuron apoptotic process, negative regulation of neuron differentiation, negative regulation of transcription from RNA polymerase II promoter, neuron development, positive regulation of apoptotic process, positive regulation of cell size, positive regulation of oligodendrocyte differentiation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, post-embryonic development, protein tetramerization, release of cytochrome c from mitochondria, response to DNA damage stimulus, response to X-ray, response to gamma radiation, response to organic nitrogen, transcription, DNA-dependent chromatin, cytosol, nucleus, transcription factor complex chromatin binding, damaged DNA binding, double-stranded DNA binding, identical protein binding, metal ion binding, p53 binding, protein binding, protein kinase binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding Human UniProtKB:O15350 TPBG PINC UniProtKB {GO:0005887=PMID:10366710, GO:0005783=GO_REF:0000019, GO:0007155=PMID:10366710} Q13641 Trophoblast glycoprotein protein 20040811 {GO:0005887=TAS, GO:0005783=IEA, GO:0007155=NAS} cell adhesion endoplasmic reticulum, integral to plasma membrane Human TPD52 IntAct UniProtKB {GO:0005515=PMID:9484778, GO:0048471=PMID:16112108, GO:0005737=PMID:15576473, GO:0046982=PMID:9484778, GO:0005783=PMID:10942595, GO:0005509=PMID:15576473, GO:0030183=PMID:15576473, GO:0009653=PMID:8632896, GO:0046903=PMID:15576473, GO:0042803=PMID:9484778} P55327 Tumor protein D52 protein 20130415 {GO:0005515=IPI, GO:0048471=IDA, GO:0005737=IDA, GO:0046982=IDA, GO:0005783=IDA, GO:0005509=IDA, GO:0030183=IEP, GO:0009653=TAS, GO:0046903=TAS, GO:0042803=IDA} B cell differentiation, anatomical structure morphogenesis, secretion cytoplasm, endoplasmic reticulum, perinuclear region of cytoplasm calcium ion binding, protein binding, protein heterodimerization activity, protein homodimerization activity Human UniProtKB:Q62393 TPD52L1 GOC UniProtKB {GO:0005515=PMID:9484778, GO:0048471=PMID:12963375, GO:0046982=PMID:9484778, GO:0006919=PMID:14761963, GO:0046330=PMID:14761963, GO:0006917=PMID:14761963, GO:0008656=PMID:14761963, GO:0042803=PMID:9484778, GO:0042802=PMID:9484778, GO:0005737=PMID:12963375, GO:0006309=PMID:14761963, GO:0043406=PMID:14761963, GO:0000086=PMID:16112108} Q16890 Tumor protein D53 protein 20130413 {GO:0005515=IPI, GO:0048471=IDA, GO:0046982=IDA, GO:0006919=IDA, GO:0046330=IDA, GO:0006917=IDA, GO:0008656=IDA, GO:0042803=IDA, GO:0042802=IPI, GO:0005737=IDA, GO:0006309=IDA, GO:0043406=IDA, GO:0000086=IDA} G2/M transition of mitotic cell cycle, activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic DNA fragmentation, induction of apoptosis, positive regulation of JNK cascade, positive regulation of MAP kinase activity cytoplasm, perinuclear region of cytoplasm cysteine-type endopeptidase activator activity involved in apoptotic process, identical protein binding, protein binding, protein heterodimerization activity, protein homodimerization activity Human TPD52L2 null null {} null null null null {} null null null TPD52L3 null null {} null null null null {} null null null TPGS1 UniProtKB UniProtKB {GO:0030424=GO_REF:0000039, GO:0005813=PMID:21399614, GO:0007288=GO_REF:0000019, GO:0005874=GO_REF:0000037, GO:0030534=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0005932=GO_REF:0000039, GO:0035085=GO_REF:0000039, GO:0030425=GO_REF:0000039} Q6ZTW0 Tubulin polyglutamylase complex subunit 1 protein 20110517 {GO:0030424=IEA, GO:0005813=IDA, GO:0007288=IEA, GO:0005874=IEA, GO:0030534=IEA, GO:0007275=IEA, GO:0005932=IEA, GO:0035085=IEA, GO:0030425=IEA} adult behavior, multicellular organismal development, sperm axoneme assembly axon, centrosome, cilium axoneme, dendrite, microtubule, microtubule basal body Human TPGS2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0005874=GO_REF:0000037} Q68CL5 Tubulin polyglutamylase complex subunit 2 protein 20130413 {GO:0005737=IEA, GO:0005874=IEA} cytoplasm, microtubule Human UniProtKB-KW:KW-0493 TPH1 Reactome UniProtKB {GO:0035902=GO_REF:0000019, GO:0043005=GO_REF:0000019, GO:0005506=GO_REF:0000002, GO:0009072=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_15352, GO:0034641=Reactome:REACT_13, GO:0004510=GO_REF:0000003, GO:0030279=GO_REF:0000019, GO:0042427=GO_REF:0000041, GO:0046219=Reactome:REACT_15439, GO:0046849=GO_REF:0000019, GO:0007623=GO_REF:0000019, GO:0016714=GO_REF:0000002, GO:0016597=GO_REF:0000002, GO:0060749=GO_REF:0000019} P17752 Tryptophan 5-hydroxylase 1 protein 20130301 {GO:0035902=IEA, GO:0043005=IEA, GO:0005506=IEA, GO:0009072=IEA, GO:0044281=TAS, GO:0005829=TAS, GO:0034641=TAS, GO:0004510=IEA, GO:0030279=IEA, GO:0042427=IEA, GO:0046219=TAS, GO:0046849=IEA, GO:0007623=IEA, GO:0016714=IEA, GO:0016597=IEA, GO:0060749=IEA} aromatic amino acid family metabolic process, bone remodeling, cellular nitrogen compound metabolic process, circadian rhythm, indolalkylamine biosynthetic process, mammary gland alveolus development, negative regulation of ossification, response to immobilization stress, serotonin biosynthetic process, small molecule metabolic process cytosol, neuron projection amino acid binding, iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen, tryptophan 5-monooxygenase activity Human TPH2 Reactome UniProtKB {GO:0071285=GO_REF:0000019, GO:0014823=GO_REF:0000019, GO:0043005=GO_REF:0000019, GO:0043627=GO_REF:0000019, GO:0005506=GO_REF:0000002, GO:0009072=GO_REF:0000002, GO:0006950=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0005829=Reactome:REACT_15352, GO:0034641=Reactome:REACT_13, GO:0051592=GO_REF:0000019, GO:0042427=GO_REF:0000041, GO:0004510=GO_REF:0000003, GO:0046219=Reactome:REACT_15439, GO:0007623=GO_REF:0000019, GO:0031667=GO_REF:0000019, GO:0016714=GO_REF:0000002, GO:0016597=GO_REF:0000002} Q8IWU9 Tryptophan 5-hydroxylase 2 protein 20130301 {GO:0071285=IEA, GO:0014823=IEA, GO:0043005=IEA, GO:0043627=IEA, GO:0005506=IEA, GO:0009072=IEA, GO:0006950=IEA, GO:0051384=IEA, GO:0044281=TAS, GO:0005829=TAS, GO:0034641=TAS, GO:0051592=IEA, GO:0042427=IEA, GO:0004510=IEA, GO:0046219=TAS, GO:0007623=IEA, GO:0031667=IEA, GO:0016714=IEA, GO:0016597=IEA} aromatic amino acid family metabolic process, cellular nitrogen compound metabolic process, cellular response to lithium ion, circadian rhythm, indolalkylamine biosynthetic process, response to activity, response to calcium ion, response to estrogen stimulus, response to glucocorticoid stimulus, response to nutrient levels, response to stress, serotonin biosynthetic process, small molecule metabolic process cytosol, neuron projection amino acid binding, iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen, tryptophan 5-monooxygenase activity Human TPI1 Reactome UniProtKB {GO:0004807=Reactome:REACT_775, GO:0005975=Reactome:REACT_474, GO:0019682=GO_REF:0000019, GO:0006094=Reactome:REACT_1520, GO:0006006=Reactome:REACT_723, GO:0044281=Reactome:REACT_111217, GO:0009790=GO_REF:0000019, GO:0006098=GO_REF:0000037, GO:0006096=Reactome:REACT_1383, GO:0005829=Reactome:REACT_775} P60174 Triosephosphate isomerase protein 20130213 {GO:0004807=EXP, GO:0005975=TAS, GO:0019682=IEA, GO:0006094=TAS, GO:0006006=TAS, GO:0044281=TAS, GO:0009790=IEA, GO:0006098=IEA, GO:0006096=TAS, GO:0005829=TAS} carbohydrate metabolic process, embryo development, gluconeogenesis, glucose metabolic process, glyceraldehyde-3-phosphate metabolic process, glycolysis, pentose-phosphate shunt, small molecule metabolic process cytosol triose-phosphate isomerase activity Human TPK1 HPA UniProtKB {GO:0004788=Reactome:REACT_11233, GO:0006772=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0009229=GO_REF:0000041, GO:0006766=Reactome:REACT_11193, GO:0016301=GO_REF:0000037, GO:0006767=Reactome:REACT_11238, GO:0044281=Reactome:REACT_111217, GO:0042723=Reactome:REACT_11117, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_11233} Q9H3S4 Thiamin pyrophosphokinase 1 protein 20111111 {GO:0004788=TAS, GO:0006772=IEA, GO:0005737=IDA, GO:0009229=IEA, GO:0006766=TAS, GO:0016301=IEA, GO:0006767=TAS, GO:0044281=TAS, GO:0042723=TAS, GO:0005524=IEA, GO:0005829=TAS} small molecule metabolic process, thiamine diphosphate biosynthetic process, thiamine metabolic process, thiamine-containing compound metabolic process, vitamin metabolic process, water-soluble vitamin metabolic process cytoplasm, cytosol ATP binding, kinase activity, thiamine diphosphokinase activity Human TPM1 HPA UniProtKB {GO:0008092=PMID:17987659, GO:0005862=PMID:8205619, GO:0055010=PMID:11136687, GO:0008016=PMID:8205619, GO:0006928=PMID:16130169, GO:0030016=GO_REF:0000019, GO:0015629=GO_REF:0000052, GO:0030017=PMID:16754800, GO:0060048=PMID:11136687, GO:0031529=PMID:15897890, GO:0005829=Reactome:REACT_20663, GO:0003065=PMID:17556658, GO:0005737=GO_REF:0000052, GO:0006937=PMID:3336363, GO:0006936=Reactome:REACT_20558, GO:0007010=PMID:12686598, GO:0005856=PMID:16130169, GO:0008307=PMID:8205619, GO:0001725=PMID:12686598, GO:0030336=PMID:15897890, GO:0030049=PMID:11136687, GO:0045214=PMID:11273725, GO:0032587=PMID:12686598, GO:0003779=PMID:12686598, GO:0032781=PMID:11136687, GO:0001701=GO_REF:0000019, GO:0045785=PMID:17721995, GO:0032059=PMID:12686598, GO:0031941=GO_REF:0000019, GO:0051496=PMID:15897890, GO:0042060=PMID:17721995, GO:0034614=PMID:12686598, GO:0005200=PMID:12686598} Q6ZN40 cDNA FLJ16459 fis, clone BRCAN2002473, moderately similar to Tropomyosin, fibroblast isoform 2 protein 20080818 {GO:0008092=IPI, GO:0005862=TAS, GO:0055010=IMP, GO:0008016=TAS, GO:0006928=TAS, GO:0030016=IEA, GO:0015629=IDA, GO:0030017=TAS, GO:0060048=IMP, GO:0031529=ISS, GO:0005829=TAS, GO:0003065=ISS, GO:0005737=IDA, GO:0006937=TAS, GO:0006936=TAS, GO:0007010=TAS, GO:0005856=TAS, GO:0008307=TAS, GO:0001725=IDA, GO:0030336=ISS, GO:0030049=ISS, GO:0045214=IMP, GO:0032587=IDA, GO:0003779=TAS, GO:0032781=ISS, GO:0001701=IEA, GO:0045785=ISS, GO:0032059=IMP, GO:0031941=IEA, GO:0051496=ISS, GO:0042060=ISS, GO:0034614=IEP, GO:0005200=TAS} cardiac muscle contraction, cellular component movement, cellular response to reactive oxygen species, cytoskeleton organization, in utero embryonic development, muscle contraction, muscle filament sliding, negative regulation of cell migration, positive regulation of ATPase activity, positive regulation of cell adhesion, positive regulation of heart rate by epinephrine, positive regulation of stress fiber assembly, regulation of heart contraction, regulation of muscle contraction, ruffle organization, sarcomere organization, ventricular cardiac muscle tissue morphogenesis, wound healing actin cytoskeleton, bleb, cytoplasm, cytoskeleton, cytosol, filamentous actin, muscle thin filament tropomyosin, myofibril, ruffle membrane, sarcomere, stress fiber actin binding, cytoskeletal protein binding, structural constituent of cytoskeleton, structural constituent of muscle Human TPM2 Reactome UniProtKB {GO:0005862=PMID:7606936, GO:0030049=Reactome:REACT_16969, GO:0006936=Reactome:REACT_20558, GO:0043462=PMID:17194691, GO:0003779=PMID:17194691, GO:0008307=PMID:7606936, GO:0005829=Reactome:REACT_20663} P07951 Tropomyosin beta chain protein 20130228 {GO:0005862=TAS, GO:0030049=TAS, GO:0006936=TAS, GO:0043462=IDA, GO:0003779=IDA, GO:0008307=TAS, GO:0005829=TAS} muscle contraction, muscle filament sliding, regulation of ATPase activity cytosol, muscle thin filament tropomyosin actin binding, structural constituent of muscle Human TPM3 HPA UniProtKB {GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0001725=PMID:16236705, GO:0006937=GO_REF:0000029, GO:0005862=PMID:3018581, GO:0030049=Reactome:REACT_16969, GO:0006936=Reactome:REACT_20558, GO:0006928=PMID:16130169, GO:0003779=GO_REF:0000037, GO:0015629=GO_REF:0000052, GO:0005856=PMID:16130169, GO:0005829=Reactome:REACT_20663} Q5VU61 Tropomyosin alpha-3 chain protein 20080818 {GO:0003674=ND, GO:0005737=IDA, GO:0001725=IDA, GO:0006937=NAS, GO:0005862=TAS, GO:0030049=TAS, GO:0006936=TAS, GO:0006928=TAS, GO:0003779=IEA, GO:0015629=IDA, GO:0005856=TAS, GO:0005829=TAS} cellular component movement, muscle contraction, muscle filament sliding, regulation of muscle contraction actin cytoskeleton, cytoplasm, cytoskeleton, cytosol, muscle thin filament tropomyosin, stress fiber actin binding, molecular_function Human TPM4 BHF-UCL UniProtKB {GO:0005862=PMID:8641132, GO:0001725=PMID:16236705, GO:0030049=Reactome:REACT_16969, GO:0005509=PMID:1836432, GO:0002102=GO_REF:0000019, GO:0006928=PMID:16130169, GO:0003779=GO_REF:0000037, GO:0005829=Reactome:REACT_20663, GO:0031941=GO_REF:0000019, GO:0006936=Reactome:REACT_20558, GO:0030863=GO_REF:0000019, GO:0005856=PMID:16130169, GO:0008307=PMID:8641132, GO:0006979=PMID:16551573} P67936 Tropomyosin alpha-4 chain protein 20091104 {GO:0005862=TAS, GO:0001725=IDA, GO:0030049=TAS, GO:0005509=NAS, GO:0002102=IEA, GO:0006928=TAS, GO:0003779=IEA, GO:0005829=TAS, GO:0031941=IEA, GO:0006936=TAS, GO:0030863=IEA, GO:0005856=TAS, GO:0008307=TAS, GO:0006979=IEP} cellular component movement, muscle contraction, muscle filament sliding, response to oxidative stress cortical cytoskeleton, cytoskeleton, cytosol, filamentous actin, muscle thin filament tropomyosin, podosome, stress fiber actin binding, calcium ion binding, structural constituent of muscle Human TPMT Reactome UniProtKB {GO:0006139=PMID:8316220, GO:0006805=Reactome:REACT_13433, GO:0008119=GO_REF:0000003, GO:0044281=Reactome:REACT_111217, GO:0032259=Reactome:REACT_6946, GO:0005829=Reactome:REACT_6779} P51580 Thiopurine S-methyltransferase protein 20130301 {GO:0006139=TAS, GO:0006805=TAS, GO:0008119=IEA, GO:0044281=TAS, GO:0032259=TAS, GO:0005829=TAS} methylation, nucleobase-containing compound metabolic process, small molecule metabolic process, xenobiotic metabolic process cytosol thiopurine S-methyltransferase activity Human TPO Reactome UniProtKB {GO:0009986=GO_REF:0000039, GO:0005886=Reactome:REACT_15539, GO:0005509=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0005739=GO_REF:0000019, GO:0034641=Reactome:REACT_13, GO:0004601=PMID:3475693, GO:0005887=PMID:2548579, GO:0004447=GO_REF:0000003, GO:0042446=GO_REF:0000037, GO:0006590=Reactome:REACT_15292, GO:0042744=GO_REF:0000037, GO:0006979=GO_REF:0000002, GO:0035162=PMID:21149635, GO:0020037=GO_REF:0000002} P07202 Thyroid peroxidase protein 20130301 {GO:0009986=IEA, GO:0005886=TAS, GO:0005509=IEA, GO:0044281=TAS, GO:0005739=IEA, GO:0034641=TAS, GO:0004601=TAS, GO:0005887=TAS, GO:0004447=IEA, GO:0042446=IEA, GO:0006590=TAS, GO:0042744=IEA, GO:0006979=IEA, GO:0035162=IDA, GO:0020037=IEA} cellular nitrogen compound metabolic process, embryonic hemopoiesis, hormone biosynthetic process, hydrogen peroxide catabolic process, response to oxidative stress, small molecule metabolic process, thyroid hormone generation cell surface, integral to plasma membrane, mitochondrion, plasma membrane calcium ion binding, heme binding, iodide peroxidase activity, peroxidase activity Human TPP1 Reactome UniProtKB {GO:0006629=PMID:9295267, GO:0005515=PMID:12134079, GO:0042277=GO_REF:0000024, GO:0008219=GO_REF:0000037, GO:0042470=GO_REF:0000039, GO:0004252=GO_REF:0000002, GO:0045453=PMID:8215436, GO:0005764=PMID:15317752, GO:0046872=GO_REF:0000037, GO:0030968=Reactome:REACT_18356, GO:0007399=PMID:9295267, GO:0005739=GO_REF:0000019, GO:0030163=PMID:10740217, GO:0004175=PMID:10679303, GO:0050885=GO_REF:0000024, GO:0006508=PMID:10965052, GO:0008240=PMID:10965052, GO:0008236=PMID:11054422, GO:0008233=PMID:9295267, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0043171=PMID:15158442, GO:0007040=GO_REF:0000024, GO:0043202=Reactome:REACT_115883} O14773 Tripeptidyl-peptidase 1 protein 20130301 {GO:0006629=TAS, GO:0005515=IPI, GO:0042277=ISS, GO:0008219=IEA, GO:0042470=IEA, GO:0004252=IEA, GO:0045453=IMP, GO:0005764=IDA, GO:0046872=IEA, GO:0030968=TAS, GO:0007399=IMP, GO:0005739=IEA, GO:0030163=NAS, GO:0004175=IMP, GO:0050885=ISS, GO:0006508=IMP, GO:0008240=IDA, GO:0008236=IMP, GO:0008233=IMP, GO:0006987=TAS, GO:0044267=TAS, GO:0043171=IMP, GO:0007040=ISS, GO:0043202=TAS} activation of signaling protein activity involved in unfolded protein response, bone resorption, cell death, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, lipid metabolic process, lysosome organization, nervous system development, neuromuscular process controlling balance, peptide catabolic process, protein catabolic process, proteolysis lysosomal lumen, lysosome, melanosome, mitochondrion endopeptidase activity, metal ion binding, peptidase activity, peptide binding, protein binding, serine-type endopeptidase activity, serine-type peptidase activity, tripeptidyl-peptidase activity Human TPP2 InterPro UniProtKB {GO:0000209=Reactome:REACT_75842, GO:0002474=Reactome:REACT_75820, GO:0005737=PMID:9974389, GO:0004175=PMID:9974389, GO:0004252=GO_REF:0000002, GO:0004177=GO_REF:0000037, GO:0006508=GO_REF:0000002, GO:0008240=PMID:9974389, GO:0005634=GO_REF:0000039, GO:0005829=Reactome:REACT_75931} Q5VZU9 Tripeptidyl-peptidase 2 protein 20130413 {GO:0000209=TAS, GO:0002474=TAS, GO:0005737=TAS, GO:0004175=TAS, GO:0004252=IEA, GO:0004177=IEA, GO:0006508=IEA, GO:0008240=TAS, GO:0005634=IEA, GO:0005829=TAS} antigen processing and presentation of peptide antigen via MHC class I, protein polyubiquitination, proteolysis cytoplasm, cytosol, nucleus aminopeptidase activity, endopeptidase activity, serine-type endopeptidase activity, tripeptidyl-peptidase activity Human InterPro:IPR000209 TPPP HPA UniProtKB {GO:0005515=PMID:15590652, GO:0008017=GO_REF:0000024, GO:0048471=PMID:15590652, GO:0005886=GO_REF:0000052, GO:0001578=GO_REF:0000024, GO:0005874=PMID:18028908, GO:0005634=PMID:18028908, GO:0046785=GO_REF:0000024, GO:0005737=PMID:18028908, GO:0031334=GO_REF:0000024, GO:0015631=GO_REF:0000024, GO:0032273=PMID:15590652, GO:0005925=GO_REF:0000052} O94811 Tubulin polymerization-promoting protein protein 20110516 {GO:0005515=IPI, GO:0008017=ISS, GO:0048471=IDA, GO:0005886=IDA, GO:0001578=ISS, GO:0005874=IDA, GO:0005634=IDA, GO:0046785=ISS, GO:0005737=IDA, GO:0031334=ISS, GO:0015631=ISS, GO:0032273=IDA, GO:0005925=IDA} microtubule bundle formation, microtubule polymerization, positive regulation of protein complex assembly, positive regulation of protein polymerization cytoplasm, focal adhesion, microtubule, nucleus, perinuclear region of cytoplasm, plasma membrane microtubule binding, protein binding, tubulin binding Human TPPP3 UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0015631=PMID:17105200, GO:0001578=PMID:17105200, GO:0005874=GO_REF:0000037} Q9BW30 Tubulin polymerization-promoting protein family member 3 protein 20090918 {GO:0005737=IEA, GO:0015631=IDA, GO:0001578=IDA, GO:0005874=IEA} microtubule bundle formation cytoplasm, microtubule tubulin binding Human TPR HPA UniProtKB {GO:0005515=PMID:17897941, GO:0005215=PMID:11952838, GO:0072686=PMID:20133940, GO:0019221=Reactome:REACT_25229, GO:0090267=PMID:19273613, GO:0006606=PMID:11952838, GO:0042803=PMID:12802065, GO:0008645=Reactome:REACT_9441, GO:0006405=PMID:11952838, GO:0034605=PMID:17897941, GO:0006404=PMID:9864356, GO:0015758=Reactome:REACT_212, GO:0031072=PMID:17897941, GO:0006611=PMID:11952838, GO:0031453=PMID:20407419, GO:0051019=PMID:18794356, GO:0031965=GO_REF:0000052, GO:0005975=Reactome:REACT_474, GO:0000122=PMID:21613532, GO:0090316=PMID:19273613, GO:0070849=PMID:18794356, GO:0034399=PMID:22401879, GO:0070840=PMID:20133940, GO:0000776=PMID:20133940, GO:0042307=PMID:18794356, GO:0005654=Reactome:REACT_115827, GO:0042306=PMID:22253824, GO:0010793=PMID:22253824, GO:0046832=PMID:22253824, GO:0043495=PMID:12802065, GO:0051301=GO_REF:0000037, GO:0042405=PMID:11839768, GO:0019898=PMID:12802065, GO:1901673=PMID:19273613, GO:0022415=Reactome:REACT_6361, GO:0007094=PMID:20133940, GO:0035457=GO_REF:0000024, GO:0004828=GO_REF:0000002, GO:0005634=PMID:15654337, GO:0044281=Reactome:REACT_111217, GO:0005635=PMID:17098863, GO:0051292=PMID:12802065, GO:0031990=PMID:17897941, GO:0003729=PMID:17897941, GO:0046827=GO_REF:0000024, GO:0010965=PMID:20133940, GO:0006434=GO_REF:0000002, GO:0005737=PMID:11952838, GO:0031647=PMID:21613532, GO:0043578=PMID:11952838, GO:0015631=PMID:20133940, GO:0005643=PMID:12802065, GO:0016032=Reactome:REACT_6256, GO:0045947=PMID:21613532, GO:0006999=PMID:15229283, GO:0046825=PMID:22253824, GO:0044615=PMID:15229283, GO:0000189=PMID:18794356, GO:0055085=Reactome:REACT_19118, GO:0005524=GO_REF:0000002, GO:0010827=Reactome:REACT_6804, GO:0007067=GO_REF:0000037, GO:0005487=PMID:22253824, GO:0003682=PMID:17897941, GO:0005868=PMID:20133940} P12270 Nucleoprotein TPR protein 20100326 {GO:0005515=IPI, GO:0005215=IMP, GO:0072686=IDA, GO:0019221=TAS, GO:0090267=IMP, GO:0006606=IMP, GO:0042803=IDA, GO:0008645=TAS, GO:0006405=IMP, GO:0034605=IDA, GO:0006404=IDA, GO:0015758=TAS, GO:0031072=IDA, GO:0006611=IMP, GO:0031453=IMP, GO:0051019=IDA, GO:0031965=IDA, GO:0005975=TAS, GO:0000122=IMP, GO:0090316=IMP, GO:0070849=IDA, GO:0034399=IDA, GO:0070840=IDA, GO:0000776=IDA, GO:0042307=IMP, GO:0005654=TAS, GO:0042306=IMP, GO:0010793=IMP, GO:0046832=IDA, GO:0043495=IMP, GO:0051301=IEA, GO:0042405=IDA, GO:0019898=IDA, GO:1901673=IMP, GO:0022415=TAS, GO:0007094=IMP, GO:0035457=ISS, GO:0004828=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0005635=IDA, GO:0051292=IMP, GO:0031990=IDA, GO:0003729=IDA, GO:0046827=ISS, GO:0010965=IMP, GO:0006434=IEA, GO:0005737=IDA, GO:0031647=IMP, GO:0043578=IMP, GO:0015631=IDA, GO:0005643=IDA, GO:0016032=TAS, GO:0045947=IMP, GO:0006999=IMP, GO:0046825=IMP, GO:0044615=IDA, GO:0000189=IMP, GO:0055085=TAS, GO:0005524=IEA, GO:0010827=TAS, GO:0007067=IEA, GO:0005487=IDA, GO:0003682=IDA, GO:0005868=IDA} MAPK import into nucleus, RNA export from nucleus, RNA import into nucleus, carbohydrate metabolic process, cell division, cellular response to heat, cellular response to interferon-alpha, cytokine-mediated signaling pathway, glucose transport, hexose transport, mRNA export from nucleus in response to heat stress, mitosis, mitotic spindle assembly checkpoint, negative regulation of RNA export from nucleus, negative regulation of transcription from RNA polymerase II promoter, negative regulation of translational initiation, nuclear matrix organization, nuclear pore complex assembly, nuclear pore organization, positive regulation of heterochromatin assembly, positive regulation of intracellular protein transport, positive regulation of mitotic cell cycle spindle assembly checkpoint, positive regulation of protein export from nucleus, positive regulation of protein import into nucleus, protein export from nucleus, protein import into nucleus, regulation of glucose transport, regulation of mRNA export from nucleus, regulation of mitotic sister chromatid separation, regulation of protein export from nucleus, regulation of protein import into nucleus, regulation of protein stability, regulation of spindle assembly involved in mitosis, response to epidermal growth factor stimulus, seryl-tRNA aminoacylation, small molecule metabolic process, transmembrane transport, viral reproduction, viral reproductive process cytoplasm, cytoplasmic dynein complex, extrinsic to membrane, kinetochore, mitotic spindle, nuclear envelope, nuclear inclusion body, nuclear membrane, nuclear periphery, nuclear pore, nuclear pore nuclear basket, nucleoplasm, nucleus ATP binding, chromatin binding, dynein complex binding, heat shock protein binding, mRNA binding, mitogen-activated protein kinase binding, nucleocytoplasmic transporter activity, protein anchor, protein binding, protein homodimerization activity, serine-tRNA ligase activity, transporter activity, tubulin binding Human TPRA1 GOC UniProtKB {GO:0006629=PMID:10342878, GO:0007186=PMID:10342878, GO:0004930=PMID:10342878, GO:0007568=PMID:10342878, GO:0016021=GO_REF:0000037} Q86W33 Transmembrane protein adipocyte-associated 1 protein 20130413 {GO:0006629=TAS, GO:0007186=TAS, GO:0004930=TAS, GO:0007568=TAS, GO:0016021=IEA} G-protein coupled receptor signaling pathway, aging, lipid metabolic process integral to membrane G-protein coupled receptor activity Human TPRKB HPA UniProtKB {GO:0005515=PMID:23455922, GO:0030163=PMID:12659830, GO:0005737=GO_REF:0000052, GO:0019901=PMID:12659830, GO:0005634=PMID:12659830, GO:0005829=PMID:12659830} Q9Y3C4 TP53RK-binding protein protein 20110516 {GO:0005515=IPI, GO:0030163=NAS, GO:0005737=IDA, GO:0019901=IPI, GO:0005634=IDA, GO:0005829=IDA} protein catabolic process cytoplasm, cytosol, nucleus protein binding, protein kinase binding Human TPRN UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0019902=GO_REF:0000002, GO:0007605=PMID:20170898, GO:0032420=GO_REF:0000024} Q4KMQ1 Taperin protein 20100422 {GO:0003674=ND, GO:0019902=IEA, GO:0007605=IMP, GO:0032420=ISS} sensory perception of sound stereocilium molecular_function, phosphatase binding Human TPSAB1 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0022617=Reactome:REACT_118572, GO:0004252=PMID:2187193, GO:0030198=Reactome:REACT_118779, GO:0006508=GO_REF:0000037, GO:0008236=PMID:2677049, GO:0005576=Reactome:REACT_118608, GO:0006952=PMID:2677049} Q15661 Tryptase alpha/beta-1 protein 20130415 {GO:0005515=IPI, GO:0022617=TAS, GO:0004252=NAS, GO:0030198=TAS, GO:0006508=IEA, GO:0008236=TAS, GO:0005576=TAS, GO:0006952=TAS} defense response, extracellular matrix disassembly, extracellular matrix organization, proteolysis extracellular region protein binding, serine-type endopeptidase activity, serine-type peptidase activity Human UniProtKB:P27986 TPSB2 PINC UniProtKB {GO:0004252=PMID:9920877, GO:0006508=GO_REF:0000029, GO:0008236=PMID:2203827, GO:0005576=GO_REF:0000029} P20231 Tryptase beta-2 protein 20030904 {GO:0004252=NAS, GO:0006508=NAS, GO:0008236=TAS, GO:0005576=NAS} proteolysis extracellular region serine-type endopeptidase activity, serine-type peptidase activity Human TPST1 PINC UniProtKB {GO:0006954=PMID:9501187, GO:0016020=PMID:9501187, GO:0000139=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0008476=GO_REF:0000003, GO:0006478=GO_REF:0000002} O60507 Protein-tyrosine sulfotransferase 1 protein 20030904 {GO:0006954=TAS, GO:0016020=TAS, GO:0000139=IEA, GO:0016021=IEA, GO:0008476=IEA, GO:0006478=IEA} inflammatory response, peptidyl-tyrosine sulfation Golgi membrane, integral to membrane, membrane protein-tyrosine sulfotransferase activity Human TPST2 LIFEdb UniProtKB {GO:0016020=PMID:9736702, GO:0000139=GO_REF:0000039, GO:0005783=GO_REF:0000054, GO:0007342=GO_REF:0000019, GO:0060468=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0008476=GO_REF:0000003, GO:0006478=GO_REF:0000002} O60704 Protein-tyrosine sulfotransferase 2 protein 20100607 {GO:0016020=TAS, GO:0000139=IEA, GO:0005783=IDA, GO:0007342=IEA, GO:0060468=IEA, GO:0016021=IEA, GO:0008476=IEA, GO:0006478=IEA} fusion of sperm to egg plasma membrane, peptidyl-tyrosine sulfation, prevention of polyspermy Golgi membrane, endoplasmic reticulum, integral to membrane, membrane protein-tyrosine sulfotransferase activity Human TPT1 ENSEMBL UniProtKB {GO:0045298=PMID:15162379, GO:0043066=GO_REF:0000019, GO:0005771=PMID:15319436, GO:2000384=GO_REF:0000019, GO:0005509=PMID:15162379, GO:0006874=PMID:15958728, GO:0042981=PMID:15162379, GO:0009615=PMID:16548883, GO:0005615=PMID:15319436, GO:0005737=PMID:15162379, GO:0019827=GO_REF:0000019, GO:0005654=GO_REF:0000019, GO:0006816=PMID:15958728, GO:0008134=GO_REF:0000019} Q8TBK7 TPT1 protein protein 20130413 {GO:0045298=IDA, GO:0043066=IEA, GO:0005771=IDA, GO:2000384=IEA, GO:0005509=IDA, GO:0006874=IC, GO:0042981=NAS, GO:0009615=IEP, GO:0005615=IDA, GO:0005737=IDA, GO:0019827=IEA, GO:0005654=IEA, GO:0006816=IC, GO:0008134=IEA} calcium ion transport, cellular calcium ion homeostasis, negative regulation of apoptotic process, negative regulation of ectoderm development, regulation of apoptotic process, response to virus, stem cell maintenance cytoplasm, extracellular space, multivesicular body, nucleoplasm, tubulin complex calcium ion binding, transcription factor binding Human Ensembl:ENSMUSP00000106519 TPTE GOC UniProtKB {GO:0007165=PMID:10598804, GO:0006470=PMID:10598804, GO:0016021=GO_REF:0000037, GO:0008138=GO_REF:0000002, GO:0005216=GO_REF:0000002, GO:0035335=PMID:10598804, GO:0004725=GO_REF:0000003} P56180 Putative tyrosine-protein phosphatase TPTE protein 20130413 {GO:0007165=TAS, GO:0006470=TAS, GO:0016021=IEA, GO:0008138=IEA, GO:0005216=IEA, GO:0035335=TAS, GO:0004725=IEA} peptidyl-tyrosine dephosphorylation, protein dephosphorylation, signal transduction integral to membrane ion channel activity, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human TPTE2 Reactome UniProtKB {GO:0006661=Reactome:REACT_120836, GO:0000139=Reactome:REACT_121091, GO:0016314=GO_REF:0000003, GO:0005789=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0008138=GO_REF:0000002, GO:0006644=Reactome:REACT_121175, GO:0005216=GO_REF:0000002, GO:0004725=GO_REF:0000002} Q6XPS3 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 protein 20130301 {GO:0006661=TAS, GO:0000139=TAS, GO:0016314=IEA, GO:0005789=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0008138=IEA, GO:0006644=TAS, GO:0005216=IEA, GO:0004725=IEA} phosphatidylinositol biosynthetic process, phospholipid metabolic process, small molecule metabolic process Golgi membrane, endoplasmic reticulum membrane, integral to membrane ion channel activity, phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity Human TPX2 HPA UniProtKB {GO:0005515=PMID:17474147, GO:0019901=PMID:19801554, GO:0060236=PMID:18663142, GO:0008283=PMID:10512675, GO:0005874=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005819=PMID:18663142, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0005525=PMID:10512675, GO:0005524=PMID:10512675, GO:0032147=PMID:19801554, GO:0007067=GO_REF:0000037, GO:0000922=PMID:14718566, GO:0005737=GO_REF:0000037, GO:0015630=GO_REF:0000054, GO:0051301=GO_REF:0000037} Q9ULW0 Targeting protein for Xklp2 protein 20081203 {GO:0005515=IPI, GO:0019901=IPI, GO:0060236=ISS, GO:0008283=TAS, GO:0005874=IEA, GO:0005730=IDA, GO:0005819=ISS, GO:0006915=IEA, GO:0005634=IDA, GO:0005525=TAS, GO:0005524=TAS, GO:0032147=IDA, GO:0007067=IEA, GO:0000922=IDA, GO:0005737=IEA, GO:0015630=IDA, GO:0051301=IEA} activation of protein kinase activity, apoptotic process, cell division, cell proliferation, mitosis, regulation of mitotic spindle organization cytoplasm, microtubule, microtubule cytoskeleton, nucleolus, nucleus, spindle, spindle pole ATP binding, GTP binding, protein binding, protein kinase binding NOT Human TRA2A UniProtKB UniProtKB {GO:0000166=GO_REF:0000002, GO:0000398=PMID:9546399, GO:0003723=GO_REF:0000037, GO:0005634=PMID:9546399, GO:0003676=GO_REF:0000002} Q13595 Transformer-2 protein homolog alpha protein 20030908 {GO:0000166=IEA, GO:0000398=IDA, GO:0003723=IEA, GO:0005634=IDA, GO:0003676=IEA} mRNA splicing, via spliceosome nucleus RNA binding, nucleic acid binding, nucleotide binding Human TRA2B UniProtKB UniProtKB {GO:0048026=PMID:15009664, GO:0005515=PMID:12165565, GO:0000166=GO_REF:0000002, GO:0000381=PMID:12165565, GO:0000398=PMID:9546399, GO:0000375=PMID:9546399, GO:0005634=PMID:9546399, GO:0003729=PMID:12165565, GO:0003676=GO_REF:0000002} P62995 Transformer-2 protein homolog beta protein 20120708 {GO:0048026=IDA, GO:0005515=IPI, GO:0000166=IEA, GO:0000381=IDA, GO:0000398=IDA, GO:0000375=TAS, GO:0005634=IDA, GO:0003729=IDA, GO:0003676=IEA} RNA splicing, via transesterification reactions, mRNA splicing, via spliceosome, positive regulation of mRNA splicing, via spliceosome, regulation of alternative mRNA splicing, via spliceosome nucleus mRNA binding, nucleic acid binding, nucleotide binding, protein binding Human UniProtKB:P0DJD3 TRABD null null {} null null null null {} null null null TRADD BHF-UCL UniProtKB {GO:0005515=PMID:19781631, GO:0006919=Reactome:REACT_1503, GO:0006915=Reactome:REACT_578, GO:0005634=GO_REF:0000039, GO:0006917=PMID:8612133, GO:0097191=PMID:18309324, GO:0097190=Reactome:REACT_1619, GO:0033209=PMID:8612133, GO:0042802=PMID:11684708, GO:0005829=Reactome:REACT_2175, GO:0043235=PMID:8612133, GO:0070513=PMID:8612133, GO:0007165=PMID:7758105, GO:0005737=PMID:11684708, GO:0051798=GO_REF:0000019, GO:0060090=PMID:8612133, GO:0004871=GO_REF:0000002, GO:0019900=PMID:8612133, GO:0043123=PMID:12761501, GO:0005856=GO_REF:0000039} Q15628 Tumor necrosis factor receptor type 1-associated DEATH domain protein protein 20090424 {GO:0005515=IPI, GO:0006919=TAS, GO:0006915=TAS, GO:0005634=IEA, GO:0006917=IDA, GO:0097191=TAS, GO:0097190=TAS, GO:0033209=TAS, GO:0042802=IPI, GO:0005829=TAS, GO:0043235=IDA, GO:0070513=IPI, GO:0007165=TAS, GO:0005737=IDA, GO:0051798=IEA, GO:0060090=IPI, GO:0004871=IEA, GO:0019900=IPI, GO:0043123=IEP, GO:0005856=IEA} activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, apoptotic signaling pathway, extrinsic apoptotic signaling pathway, induction of apoptosis, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of hair follicle development, signal transduction, tumor necrosis factor-mediated signaling pathway cytoplasm, cytoskeleton, cytosol, nucleus, receptor complex binding, bridging, death domain binding, identical protein binding, kinase binding, protein binding, signal transducer activity Human UniProtKB:Q13546 TRAF1 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0007165=GO_REF:0000002, GO:0005737=PMID:8069916, GO:0006461=PMID:8069916, GO:0051092=PMID:10692572, GO:0006915=GO_REF:0000037, GO:0031996=PMID:11279055, GO:0042981=PMID:10692572, GO:0008270=GO_REF:0000002, GO:0043123=PMID:19641626, GO:0031625=PMID:11279055} Q13077 TNF receptor-associated factor 1 protein 20130415 {GO:0005515=IPI, GO:0007165=IEA, GO:0005737=TAS, GO:0006461=TAS, GO:0051092=IDA, GO:0006915=IEA, GO:0031996=IPI, GO:0042981=IDA, GO:0008270=IEA, GO:0043123=RCA, GO:0031625=IPI} apoptotic process, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB transcription factor activity, protein complex assembly, regulation of apoptotic process, signal transduction cytoplasm protein binding, thioesterase binding, ubiquitin protein ligase binding, zinc ion binding Human UniProtKB:Q14161 TRAF2 BHF-UCL UniProtKB {GO:0005515=PMID:21903422, GO:0035631=GO_REF:0000024, GO:0004842=PMID:15258597, GO:0031996=PMID:11279055, GO:0043623=GO_REF:0000024, GO:0042802=PMID:20562859, GO:0005829=Reactome:REACT_25327, GO:0046328=GO_REF:0000019, GO:0030163=GO_REF:0000019, GO:0070207=PMID:20447407, GO:0051091=PMID:12296995, GO:0005737=GO_REF:0000052, GO:0070534=PMID:15258597, GO:0051092=PMID:12296995, GO:0004871=PMID:8702708, GO:0043507=PMID:11907583, GO:0031625=PMID:11279055, GO:0005164=PMID:11279055, GO:0007250=PMID:15125833, GO:0046625=PMID:20577214, GO:0006919=Reactome:REACT_1503, GO:0032743=PMID:15125833, GO:0006915=Reactome:REACT_578, GO:0042981=PMID:11907583, GO:0002726=PMID:15125833, GO:0097190=Reactome:REACT_1619, GO:0033209=PMID:11907583, GO:0051865=PMID:16378096, GO:0051023=GO_REF:0000019, GO:0007165=PMID:8702708, GO:0006461=PMID:8702708, GO:0045087=Reactome:REACT_6802, GO:0050870=PMID:15125833, GO:0009898=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0019899=PMID:16636664, GO:0005174=GO_REF:0000024} Q12933 TNF receptor-associated factor 2 protein 20110308 {GO:0005515=IPI, GO:0035631=ISS, GO:0004842=IDA, GO:0031996=IPI, GO:0043623=ISS, GO:0042802=IPI, GO:0005829=TAS, GO:0046328=IEA, GO:0030163=IEA, GO:0070207=IPI, GO:0051091=IMP, GO:0005737=IDA, GO:0070534=IDA, GO:0051092=IMP, GO:0004871=NAS, GO:0043507=IDA, GO:0031625=IPI, GO:0005164=IPI, GO:0007250=IMP, GO:0046625=IDA, GO:0006919=TAS, GO:0032743=IMP, GO:0006915=TAS, GO:0042981=IDA, GO:0002726=IMP, GO:0097190=TAS, GO:0033209=IDA, GO:0051865=TAS, GO:0051023=IEA, GO:0007165=TAS, GO:0006461=TAS, GO:0045087=TAS, GO:0050870=IC, GO:0009898=ISS, GO:0008270=IEA, GO:0019899=IPI, GO:0005174=ISS} activation of NF-kappaB-inducing kinase activity, activation of cysteine-type endopeptidase activity involved in apoptotic process, apoptotic process, apoptotic signaling pathway, cellular protein complex assembly, innate immune response, positive regulation of JUN kinase activity, positive regulation of NF-kappaB transcription factor activity, positive regulation of T cell activation, positive regulation of T cell cytokine production, positive regulation of interleukin-2 production, positive regulation of sequence-specific DNA binding transcription factor activity, protein K63-linked ubiquitination, protein autoubiquitination, protein catabolic process, protein complex assembly, protein homotrimerization, regulation of JNK cascade, regulation of apoptotic process, regulation of immunoglobulin secretion, signal transduction, tumor necrosis factor-mediated signaling pathway CD40 receptor complex, cytoplasm, cytosol, internal side of plasma membrane CD40 receptor binding, enzyme binding, identical protein binding, protein binding, signal transducer activity, sphingolipid binding, thioesterase binding, tumor necrosis factor receptor binding, ubiquitin protein ligase binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:P09211 TRAF3 BHF-UCL UniProtKB {GO:0050688=GO_REF:0000024, GO:0005515=PMID:23153539, GO:0035631=GO_REF:0000024, GO:0004842=Reactome:REACT_120820, GO:0034142=Reactome:REACT_6894, GO:0031996=PMID:11279055, GO:0001817=GO_REF:0000024, GO:0005829=Reactome:REACT_121070, GO:0030162=PMID:20185819, GO:0005739=GO_REF:0000039, GO:0002756=Reactome:REACT_6809, GO:0032648=GO_REF:0000024, GO:0004871=PMID:7533327, GO:0034138=Reactome:REACT_6783, GO:0032480=Reactome:REACT_25271, GO:0031625=PMID:11279055, GO:0019901=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0042981=GO_REF:0000002, GO:0032088=PMID:20185819, GO:0006917=PMID:10799510, GO:0002224=Reactome:REACT_6966, GO:0033209=PMID:20185819, GO:0007165=PMID:7530216, GO:0008063=GO_REF:0000002, GO:0045087=Reactome:REACT_6802, GO:0009898=GO_REF:0000024, GO:0035666=Reactome:REACT_25281, GO:0008270=GO_REF:0000002, GO:0005768=GO_REF:0000039} Q13114 TNF receptor-associated factor 3 protein 20110110 {GO:0050688=ISS, GO:0005515=IPI, GO:0035631=ISS, GO:0004842=TAS, GO:0034142=TAS, GO:0031996=IPI, GO:0001817=ISS, GO:0005829=TAS, GO:0030162=IMP, GO:0005739=IEA, GO:0002756=TAS, GO:0032648=ISS, GO:0004871=TAS, GO:0034138=TAS, GO:0032480=TAS, GO:0031625=IPI, GO:0019901=IEA, GO:0006915=IEA, GO:0042981=IEA, GO:0032088=IMP, GO:0006917=TAS, GO:0002224=TAS, GO:0033209=IMP, GO:0007165=TAS, GO:0008063=IEA, GO:0045087=TAS, GO:0009898=ISS, GO:0035666=TAS, GO:0008270=IEA, GO:0005768=IEA} MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, Toll signaling pathway, apoptotic process, induction of apoptosis, innate immune response, negative regulation of NF-kappaB transcription factor activity, negative regulation of type I interferon production, regulation of apoptotic process, regulation of cytokine production, regulation of defense response to virus, regulation of interferon-beta production, regulation of proteolysis, signal transduction, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor signaling pathway, tumor necrosis factor-mediated signaling pathway CD40 receptor complex, cytosol, endosome, internal side of plasma membrane, mitochondrion protein binding, protein kinase binding, signal transducer activity, thioesterase binding, ubiquitin protein ligase binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q60803 TRAF3IP1 IntAct UniProtKB {GO:0005515=PMID:17043677, GO:0008017=GO_REF:0000002, GO:0005737=GO_REF:0000037, GO:0005856=GO_REF:0000039} Q8TDR0 TRAF3-interacting protein 1 protein 20130415 {GO:0005515=IPI, GO:0008017=IEA, GO:0005737=IEA, GO:0005856=IEA} cytoplasm, cytoskeleton microtubule binding, protein binding Human UniProtKB:Q9NRI5 TRAF3IP2 UniProtKB UniProtKB {GO:0005515=PMID:12459498, GO:0035556=PMID:10962033, GO:0001783=GO_REF:0000019, GO:0006959=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0043123=PMID:12761501, GO:0048305=GO_REF:0000019} O43734 Adapter protein CIKS protein 20110915 {GO:0005515=IPI, GO:0035556=NAS, GO:0001783=IEA, GO:0006959=IEA, GO:0005575=ND, GO:0043123=IEP, GO:0048305=IEA} B cell apoptotic process, humoral immune response, immunoglobulin secretion, intracellular signal transduction, positive regulation of I-kappaB kinase/NF-kappaB cascade cellular_component protein binding Human UniProtKB:Q9Y4K3 TRAF3IP3 IntAct UniProtKB {GO:0005515=PMID:18782753, GO:0016021=GO_REF:0000037} Q9Y228 TRAF3-interacting JNK-activating modulator protein 20130415 {GO:0005515=IPI, GO:0016021=IEA} integral to membrane protein binding Human UniProtKB:Q9Y6E0 TRAF4 IntAct UniProtKB {GO:0005515=PMID:10514511, GO:0004842=GO_REF:0000002, GO:0048471=GO_REF:0000039, GO:0090073=PMID:16157600, GO:0007250=GO_REF:0000002, GO:0007585=GO_REF:0000019, GO:0019901=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0050699=PMID:19937093, GO:0030323=GO_REF:0000019, GO:0046330=PMID:16157600, GO:0006915=GO_REF:0000037, GO:0031996=PMID:11279055, GO:0005634=PMID:18087216, GO:0042981=GO_REF:0000002, GO:0003677=PMID:7592751, GO:0007165=PMID:7592751, GO:0005737=PMID:16157600, GO:0045860=PMID:16157600, GO:0008270=GO_REF:0000002, GO:0005923=GO_REF:0000039, GO:0005856=GO_REF:0000039, GO:0031625=PMID:11279055} Q9BUZ4 TNF receptor-associated factor 4 protein 20130415 {GO:0005515=IPI, GO:0004842=IEA, GO:0048471=IEA, GO:0090073=IDA, GO:0007250=IEA, GO:0007585=IEA, GO:0019901=IEA, GO:0005886=IEA, GO:0050699=IPI, GO:0030323=IEA, GO:0046330=IDA, GO:0006915=IEA, GO:0031996=IPI, GO:0005634=IDA, GO:0042981=IEA, GO:0003677=TAS, GO:0007165=TAS, GO:0005737=IDA, GO:0045860=IDA, GO:0008270=IEA, GO:0005923=IEA, GO:0005856=IEA, GO:0031625=IPI} activation of NF-kappaB-inducing kinase activity, apoptotic process, positive regulation of JNK cascade, positive regulation of protein homodimerization activity, positive regulation of protein kinase activity, regulation of apoptotic process, respiratory gaseous exchange, respiratory tube development, signal transduction cytoplasm, cytoskeleton, nucleus, perinuclear region of cytoplasm, plasma membrane, tight junction DNA binding, WW domain binding, protein binding, protein kinase binding, thioesterase binding, ubiquitin protein ligase binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:P07174 TRAF5 BHF-UCL UniProtKB {GO:0005515=PMID:9162022, GO:0035631=GO_REF:0000024, GO:0004842=GO_REF:0000002, GO:0008284=GO_REF:0000019, GO:0005813=PMID:21399614, GO:0006915=GO_REF:0000037, GO:0042981=GO_REF:0000002, GO:0031996=PMID:11279055, GO:0007165=PMID:9511754, GO:0051091=PMID:12296995, GO:0005737=GO_REF:0000039, GO:0051092=PMID:12296995, GO:0009898=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0004871=GO_REF:0000019, GO:0043123=PMID:12761501, GO:0031625=PMID:11279055} O00463 TNF receptor-associated factor 5 protein 20100721 {GO:0005515=IPI, GO:0035631=ISS, GO:0004842=IEA, GO:0008284=IEA, GO:0005813=IDA, GO:0006915=IEA, GO:0042981=IEA, GO:0031996=IPI, GO:0007165=TAS, GO:0051091=IMP, GO:0005737=IEA, GO:0051092=IMP, GO:0009898=ISS, GO:0008270=IEA, GO:0004871=IEA, GO:0043123=IEP, GO:0031625=IPI} apoptotic process, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of cell proliferation, positive regulation of sequence-specific DNA binding transcription factor activity, regulation of apoptotic process, signal transduction CD40 receptor complex, centrosome, cytoplasm, internal side of plasma membrane protein binding, signal transducer activity, thioesterase binding, ubiquitin protein ligase binding, ubiquitin-protein ligase activity, zinc ion binding Human TRAF6 HPA UniProtKB {GO:0005515=PMID:21988832, GO:0035631=GO_REF:0000024, GO:0004842=Reactome:REACT_25022, GO:0045453=GO_REF:0000019, GO:0007249=Reactome:REACT_25351, GO:0051403=Reactome:REACT_21308, GO:0002756=Reactome:REACT_6809, GO:0070534=PMID:17135271, GO:0002755=Reactome:REACT_27215, GO:0031666=GO_REF:0000019, GO:0043123=Reactome:REACT_24918, GO:0005938=GO_REF:0000039, GO:0031625=PMID:11279055, GO:0000209=PMID:19675569, GO:0005811=GO_REF:0000024, GO:0045410=GO_REF:0000019, GO:0031965=GO_REF:0000052, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0019901=PMID:19713527, GO:0034134=Reactome:REACT_7980, GO:0001843=GO_REF:0000019, GO:0031435=PMID:10094049, GO:0002726=PMID:15125833, GO:0000122=PMID:18093978, GO:0002224=Reactome:REACT_9020, GO:0051865=PMID:17135271, GO:0045084=GO_REF:0000019, GO:0001503=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0050870=PMID:15125833, GO:0009898=GO_REF:0000024, GO:0035666=Reactome:REACT_25281, GO:0034166=Reactome:REACT_9027, GO:0008270=GO_REF:0000002, GO:0045892=PMID:18093978, GO:0034162=Reactome:REACT_9047, GO:0010008=Reactome:REACT_25322, GO:0050852=Reactome:REACT_12526, GO:0048471=PMID:11751921, GO:2000679=PMID:11751921, GO:0034142=Reactome:REACT_6894, GO:0005886=Reactome:REACT_121298, GO:0042826=PMID:18093978, GO:0031293=Reactome:REACT_13443, GO:0070423=Reactome:REACT_75776, GO:0005634=GO_REF:0000052, GO:0042088=GO_REF:0000019, GO:0031996=PMID:11279055, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_120733, GO:0032147=PMID:17135271, GO:0000187=Reactome:REACT_21399, GO:0019886=GO_REF:0000019, GO:0051091=PMID:12296995, GO:0005737=GO_REF:0000052, GO:0051092=PMID:12296995, GO:0045944=PMID:11751921, GO:0042102=GO_REF:0000019, GO:0042475=GO_REF:0000019, GO:0043507=PMID:11751921, GO:0043011=GO_REF:0000019, GO:0004871=GO_REF:0000002, GO:0048468=GO_REF:0000019, GO:0034138=Reactome:REACT_6783, GO:0070498=GO_REF:0000019, GO:0070555=PMID:17135271, GO:0048011=Reactome:REACT_13776, GO:0043066=Reactome:REACT_13537, GO:0007250=PMID:15125833, GO:0032743=PMID:15125833, GO:0005730=GO_REF:0000052, GO:0007254=Reactome:REACT_21368, GO:0030316=GO_REF:0000019, GO:0006915=Reactome:REACT_13643, GO:0045672=PMID:17135271, GO:0043422=PMID:19713527, GO:0097190=Reactome:REACT_13720, GO:0048661=GO_REF:0000019, GO:0051023=GO_REF:0000019, GO:0006461=GO_REF:0000019, GO:0047485=PMID:14530355, GO:0034146=Reactome:REACT_9061} Q9Y4K3 TNF receptor-associated factor 6 protein 20101115 {GO:0005515=IPI, GO:0035631=ISS, GO:0004842=TAS, GO:0045453=IEA, GO:0007249=TAS, GO:0051403=TAS, GO:0002756=TAS, GO:0070534=IGI, GO:0002755=TAS, GO:0031666=IEA, GO:0043123=TAS, GO:0005938=IEA, GO:0031625=IPI, GO:0000209=IDA, GO:0005811=ISS, GO:0045410=IEA, GO:0031965=IDA, GO:0038124=TAS, GO:0038123=TAS, GO:0019901=IPI, GO:0034134=TAS, GO:0001843=IEA, GO:0031435=IPI, GO:0002726=IMP, GO:0000122=IMP, GO:0002224=TAS, GO:0051865=IDA, GO:0045084=IEA, GO:0001503=IEA, GO:0045087=TAS, GO:0050870=IC, GO:0009898=ISS, GO:0035666=TAS, GO:0034166=TAS, GO:0008270=IEA, GO:0045892=IMP, GO:0034162=TAS, GO:0010008=TAS, GO:0050852=TAS, GO:0048471=IDA, GO:2000679=IDA, GO:0034142=TAS, GO:0005886=TAS, GO:0042826=IPI, GO:0031293=TAS, GO:0070423=TAS, GO:0005634=IDA, GO:0042088=IEA, GO:0031996=IPI, GO:0035872=TAS, GO:0005829=TAS, GO:0032147=IDA, GO:0000187=TAS, GO:0019886=IEA, GO:0051091=IMP, GO:0005737=IDA, GO:0051092=IMP, GO:0045944=IDA, GO:0042102=IEA, GO:0042475=IEA, GO:0043507=IDA, GO:0043011=IEA, GO:0004871=IEA, GO:0048468=IEA, GO:0034138=TAS, GO:0070498=IEA, GO:0070555=IDA, GO:0048011=TAS, GO:0043066=TAS, GO:0007250=IMP, GO:0032743=IMP, GO:0005730=IDA, GO:0007254=TAS, GO:0030316=IEA, GO:0006915=TAS, GO:0045672=IDA, GO:0043422=IPI, GO:0097190=TAS, GO:0048661=IEA, GO:0051023=IEA, GO:0006461=IEA, GO:0047485=IPI, GO:0034146=TAS} I-kappaB kinase/NF-kappaB cascade, JNK cascade, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, T cell receptor signaling pathway, T-helper 1 type immune response, TRIF-dependent toll-like receptor signaling pathway, activation of MAPK activity, activation of NF-kappaB-inducing kinase activity, activation of protein kinase activity, antigen processing and presentation of exogenous peptide antigen via MHC class II, apoptotic process, apoptotic signaling pathway, bone resorption, cell development, innate immune response, interleukin-1-mediated signaling pathway, membrane protein intracellular domain proteolysis, myeloid dendritic cell differentiation, negative regulation of apoptotic process, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, neural tube closure, neurotrophin TRK receptor signaling pathway, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, nucleotide-binding oligomerization domain containing signaling pathway, odontogenesis of dentin-containing tooth, ossification, osteoclast differentiation, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of JUN kinase activity, positive regulation of NF-kappaB transcription factor activity, positive regulation of T cell activation, positive regulation of T cell cytokine production, positive regulation of T cell proliferation, positive regulation of interleukin-12 biosynthetic process, positive regulation of interleukin-2 production, positive regulation of interleukin-6 biosynthetic process, positive regulation of lipopolysaccharide-mediated signaling pathway, positive regulation of osteoclast differentiation, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of smooth muscle cell proliferation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription regulatory region DNA binding, protein K63-linked ubiquitination, protein autoubiquitination, protein complex assembly, protein polyubiquitination, regulation of immunoglobulin secretion, response to interleukin-1, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway CD40 receptor complex, cell cortex, cytoplasm, cytosol, endosome membrane, internal side of plasma membrane, lipid particle, nuclear membrane, nucleolus, nucleus, perinuclear region of cytoplasm, plasma membrane histone deacetylase binding, mitogen-activated protein kinase kinase kinase binding, protein N-terminus binding, protein binding, protein kinase B binding, protein kinase binding, signal transducer activity, thioesterase binding, ubiquitin protein ligase binding, ubiquitin-protein ligase activity, zinc ion binding Human TRAF7 HPA UniProtKB {GO:0005515=PMID:21903422, GO:0006355=GO_REF:0000037, GO:0004842=PMID:14743216, GO:0016567=PMID:14743216, GO:0005886=GO_REF:0000052, GO:0000151=PMID:14743216, GO:0006915=PMID:15001576, GO:0042981=PMID:15001576, GO:0006351=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0000185=PMID:14743216, GO:0016023=GO_REF:0000039, GO:0008270=PMID:14743216, GO:0043410=PMID:15001576} Q6Q0C0 E3 ubiquitin-protein ligase TRAF7 protein 20111111 {GO:0005515=IPI, GO:0006355=IEA, GO:0004842=IDA, GO:0016567=IDA, GO:0005886=IDA, GO:0000151=IDA, GO:0006915=IDA, GO:0042981=IMP, GO:0006351=IEA, GO:0043231=IDA, GO:0000185=IDA, GO:0016023=IEA, GO:0008270=NAS, GO:0043410=IDA} activation of MAPKKK activity, apoptotic process, positive regulation of MAPK cascade, protein ubiquitination, regulation of apoptotic process, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasmic membrane-bounded vesicle, intracellular membrane-bounded organelle, plasma membrane, ubiquitin ligase complex protein binding, ubiquitin-protein ligase activity, zinc ion binding Human TRAFD1 UniProtKB UniProtKB {GO:0034097=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0045824=GO_REF:0000024} O14545 TRAF-type zinc finger domain-containing protein 1 protein 20100625 {GO:0034097=IEA, GO:0046872=IEA, GO:0045824=ISS} negative regulation of innate immune response, response to cytokine stimulus metal ion binding Human UniProtKB:Q3UDK1 TRAIP HPA UniProtKB {GO:0005515=PMID:17474147, GO:0007165=PMID:9104814, GO:0048471=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0008283=PMID:9104814, GO:0008270=GO_REF:0000002, GO:0006917=PMID:9104814, GO:0005057=GO_REF:0000019} Q9BWF2 TRAF-interacting protein protein 20110516 {GO:0005515=IPI, GO:0007165=TAS, GO:0048471=IEA, GO:0005737=IDA, GO:0005886=IDA, GO:0008283=TAS, GO:0008270=IEA, GO:0006917=TAS, GO:0005057=IEA} cell proliferation, induction of apoptosis, signal transduction cytoplasm, perinuclear region of cytoplasm, plasma membrane protein binding, receptor signaling protein activity, zinc ion binding Human TRAK1 IntAct UniProtKB {GO:0005515=PMID:19135897, GO:0005739=PMID:15644324, GO:0005737=PMID:19528298, GO:0006357=GO_REF:0000024, GO:0006493=GO_REF:0000024, GO:0008333=PMID:18675823, GO:0005634=GO_REF:0000024, GO:0006605=GO_REF:0000024, GO:0050811=GO_REF:0000019, GO:0005769=PMID:18675823} Q9UPV9 Trafficking kinesin-binding protein 1 protein 20130415 {GO:0005515=IPI, GO:0005739=IDA, GO:0005737=IDA, GO:0006357=ISS, GO:0006493=ISS, GO:0008333=IDA, GO:0005634=ISS, GO:0006605=ISS, GO:0050811=IEA, GO:0005769=IDA} endosome to lysosome transport, protein O-linked glycosylation, protein targeting, regulation of transcription from RNA polymerase II promoter cytoplasm, early endosome, mitochondrion, nucleus GABA receptor binding, protein binding Human UniProtKB:Q8IXI2 TRAK2 HGNC UniProtKB {GO:0005515=PMID:15644324, GO:0005739=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0005886=PMID:12034717, GO:0006493=GO_REF:0000019, GO:0006357=GO_REF:0000019, GO:0005102=PMID:12034717, GO:0005634=GO_REF:0000019, GO:0050811=PMID:15644324, GO:0006605=GO_REF:0000019, GO:0019899=GO_REF:0000019, GO:0005769=GO_REF:0000039} O60296 Trafficking kinesin-binding protein 2 protein 20060104 {GO:0005515=IPI, GO:0005739=ISS, GO:0005737=ISS, GO:0005886=ISS, GO:0006493=IEA, GO:0006357=IEA, GO:0005102=ISS, GO:0005634=IEA, GO:0050811=NAS, GO:0006605=IEA, GO:0019899=IEA, GO:0005769=IEA} protein O-linked glycosylation, protein targeting, regulation of transcription from RNA polymerase II promoter cytoplasm, early endosome, mitochondrion, nucleus, plasma membrane GABA receptor binding, enzyme binding, protein binding, receptor binding Human UniProtKB:O60282 TRAM1 Reactome UniProtKB {GO:0005515=PMID:18555783, GO:0010467=Reactome:REACT_71, GO:0005783=PMID:1315422, GO:0006614=Reactome:REACT_115902, GO:0019048=GO_REF:0000037, GO:0006613=PMID:1315422, GO:0005789=GO_REF:0000039, GO:0004872=PMID:1315422, GO:0016021=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0006412=Reactome:REACT_1014} Q15629 Translocating chain-associated membrane protein 1 protein 20130213 {GO:0005515=IPI, GO:0010467=TAS, GO:0005783=TAS, GO:0006614=TAS, GO:0019048=IEA, GO:0006613=TAS, GO:0005789=IEA, GO:0004872=TAS, GO:0016021=IEA, GO:0044267=TAS, GO:0006412=TAS} SRP-dependent cotranslational protein targeting to membrane, cellular protein metabolic process, cotranslational protein targeting to membrane, gene expression, translation, virus-host interaction endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane protein binding, receptor activity Human TRAM2 UniProtKB UniProtKB {GO:0005515=PMID:14749390, GO:0032964=PMID:14749390, GO:0016021=GO_REF:0000037, GO:0015031=GO_REF:0000037} Q15035 Translocating chain-associated membrane protein 2 protein 20090914 {GO:0005515=IPI, GO:0032964=IMP, GO:0016021=IEA, GO:0015031=IEA} collagen biosynthetic process, protein transport integral to membrane protein binding Human UniProtKB:P16615-1 TRANK1 InterPro UniProtKB {GO:0004003=GO_REF:0000002, GO:0016787=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0003677=GO_REF:0000002} O15050 TPR and ankyrin repeat-containing protein 1 protein 20130413 {GO:0004003=IEA, GO:0016787=IEA, GO:0005524=IEA, GO:0003677=IEA} ATP binding, ATP-dependent DNA helicase activity, DNA binding, hydrolase activity Human InterPro:IPR014017 TRAP1 BHF-UCL UniProtKB {GO:0005739=GO_REF:0000039, GO:0005164=PMID:7876093, GO:0006457=GO_REF:0000002, GO:0006950=GO_REF:0000002, GO:0034599=PMID:16551573, GO:0005575=GO_REF:0000015, GO:0051082=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q12931 Heat shock protein 75 kDa, mitochondrial protein 20091104 {GO:0005739=IEA, GO:0005164=NAS, GO:0006457=IEA, GO:0006950=IEA, GO:0034599=IDA, GO:0005575=ND, GO:0051082=IEA, GO:0005524=IEA} cellular response to oxidative stress, protein folding, response to stress cellular_component, mitochondrion ATP binding, tumor necrosis factor receptor binding, unfolded protein binding Human TRAPPC1 UniProtKB UniProtKB {GO:0006888=GO_REF:0000002, GO:0005801=GO_REF:0000002, GO:0005783=GO_REF:0000039, GO:0030008=GO_REF:0000019} Q9Y5R8 Trafficking protein particle complex subunit 1 protein 20130413 {GO:0006888=IEA, GO:0005801=IEA, GO:0005783=IEA, GO:0030008=IEA} ER to Golgi vesicle-mediated transport TRAPP complex, cis-Golgi network, endoplasmic reticulum Human UniProtKB-SubCell:SL-0095 TRAPPC10 GOC UniProtKB {GO:0005794=GO_REF:0000039, GO:0035725=PMID:7633421, GO:0016021=PMID:9196060, GO:0015081=PMID:7633421, GO:0006814=PMID:7633421, GO:0016192=GO_REF:0000037} P48553 Trafficking protein particle complex subunit 10 protein 20130413 {GO:0005794=IEA, GO:0035725=TAS, GO:0016021=TAS, GO:0015081=TAS, GO:0006814=TAS, GO:0016192=IEA} sodium ion transmembrane transport, sodium ion transport, vesicle-mediated transport Golgi apparatus, integral to membrane sodium ion transmembrane transporter activity Human TRAPPC2 BHF-UCL UniProtKB {GO:0005515=PMID:11134351, GO:0006888=PMID:10431248, GO:0005622=GO_REF:0000002, GO:0048471=PMID:12681486, GO:0001501=PMID:10431248, GO:0006355=PMID:11134351, GO:0005794=GO_REF:0000039, GO:0005783=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037, GO:0044325=PMID:12681486, GO:0008134=PMID:11134351} P0DI81 Trafficking protein particle complex subunit 2 protein 20130215 {GO:0005515=IPI, GO:0006888=NAS, GO:0005622=IEA, GO:0048471=IDA, GO:0001501=IMP, GO:0006355=IDA, GO:0005794=IEA, GO:0005783=IEA, GO:0005634=IEA, GO:0006351=IEA, GO:0044325=IPI, GO:0008134=IPI} ER to Golgi vesicle-mediated transport, regulation of transcription, DNA-dependent, skeletal system development, transcription, DNA-dependent Golgi apparatus, endoplasmic reticulum, intracellular, nucleus, perinuclear region of cytoplasm ion channel binding, protein binding, transcription factor binding Human TRAPPC2L HPA UniProtKB {GO:0006888=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0048471=GO_REF:0000039, GO:0005794=GO_REF:0000039, GO:0005783=GO_REF:0000039} Q9UL33 Trafficking protein particle complex subunit 2-like protein protein 20110516 {GO:0006888=IEA, GO:0005622=IEA, GO:0005737=IDA, GO:0048471=IEA, GO:0005794=IEA, GO:0005783=IEA} ER to Golgi vesicle-mediated transport Golgi apparatus, cytoplasm, endoplasmic reticulum, intracellular, perinuclear region of cytoplasm Human TRAPPC3 HPA UniProtKB {GO:0006888=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0000139=GO_REF:0000019, GO:0005783=GO_REF:0000039, GO:0030008=GO_REF:0000019, GO:0005829=GO_REF:0000019} O43617 Trafficking protein particle complex subunit 3 protein 20101115 {GO:0006888=IEA, GO:0005737=IDA, GO:0005794=IDA, GO:0000139=IEA, GO:0005783=IEA, GO:0030008=IEA, GO:0005829=IEA} ER to Golgi vesicle-mediated transport Golgi apparatus, Golgi membrane, TRAPP complex, cytoplasm, cytosol, endoplasmic reticulum Human TRAPPC4 UniProtKB UniProtKB {GO:0006888=GO_REF:0000002, GO:0005801=GO_REF:0000002, GO:0005795=PMID:11018053, GO:0005783=GO_REF:0000039, GO:0030008=GO_REF:0000019, GO:0045202=PMID:11018053, GO:0030425=PMID:11018053, GO:0016358=PMID:11018053, GO:0008021=PMID:11018053} Q9Y296 Trafficking protein particle complex subunit 4 protein 20041006 {GO:0006888=IEA, GO:0005801=IEA, GO:0005795=ISS, GO:0005783=IEA, GO:0030008=IEA, GO:0045202=ISS, GO:0030425=ISS, GO:0016358=ISS, GO:0008021=ISS} ER to Golgi vesicle-mediated transport, dendrite development Golgi stack, TRAPP complex, cis-Golgi network, dendrite, endoplasmic reticulum, synapse, synaptic vesicle Human UniProtKB:Q9ES56 TRAPPC5 UniProtKB UniProtKB {GO:0005783=GO_REF:0000039, GO:0030008=GO_REF:0000019, GO:0016192=GO_REF:0000037} Q8IUR0 Trafficking protein particle complex subunit 5 protein 20130413 {GO:0005783=IEA, GO:0030008=IEA, GO:0016192=IEA} vesicle-mediated transport TRAPP complex, endoplasmic reticulum Human UniProtKB-SubCell:SL-0095 TRAPPC6A IntAct UniProtKB {GO:0005515=PMID:23088713, GO:0005794=GO_REF:0000039, GO:0005783=GO_REF:0000039, GO:0016192=GO_REF:0000037} O75865 Trafficking protein particle complex subunit 6A protein 20130415 {GO:0005515=IPI, GO:0005794=IEA, GO:0005783=IEA, GO:0016192=IEA} vesicle-mediated transport Golgi apparatus, endoplasmic reticulum protein binding Human UniProtKB:P09022 TRAPPC6B UniProtKB UniProtKB {GO:0005794=GO_REF:0000039, GO:0005783=GO_REF:0000039, GO:0016192=GO_REF:0000037} Q86SZ2 Trafficking protein particle complex subunit 6B protein 20130413 {GO:0005794=IEA, GO:0005783=IEA, GO:0016192=IEA} vesicle-mediated transport Golgi apparatus, endoplasmic reticulum Human UniProtKB-SubCell:SL-0132 TRAPPC8 UniProtKB UniProtKB {GO:0006888=GO_REF:0000029, GO:0005801=GO_REF:0000029, GO:0005794=GO_REF:0000039} Q9Y2L5 Trafficking protein particle complex subunit 8 protein 20021106 {GO:0006888=NAS, GO:0005801=NAS, GO:0005794=IEA} ER to Golgi vesicle-mediated transport Golgi apparatus, cis-Golgi network Human TRAPPC9 UniProtKB UniProtKB {GO:0005794=GO_REF:0000039, GO:0005783=GO_REF:0000039, GO:0030154=GO_REF:0000037} Q96Q05 Trafficking protein particle complex subunit 9 protein 20130413 {GO:0005794=IEA, GO:0005783=IEA, GO:0030154=IEA} cell differentiation Golgi apparatus, endoplasmic reticulum Human UniProtKB-SubCell:SL-0132 TRAT1 Reactome UniProtKB {GO:0050852=Reactome:REACT_12526, GO:0048011=Reactome:REACT_11061, GO:0005886=Reactome:REACT_147854, GO:0048015=Reactome:REACT_12464, GO:0050862=PMID:11390434, GO:0050850=PMID:11390434, GO:0007165=PMID:9687533, GO:0006968=PMID:9687533, GO:0007173=Reactome:REACT_9417, GO:0005887=PMID:9687533, GO:0008543=Reactome:REACT_9470, GO:0042101=PMID:11390434, GO:0045087=Reactome:REACT_6802, GO:0005068=PMID:9687533, GO:0001920=PMID:11390434, GO:0051051=PMID:11390434} Q6PIZ9 T-cell receptor-associated transmembrane adapter 1 protein 20071029 {GO:0050852=TAS, GO:0048011=TAS, GO:0005886=TAS, GO:0048015=TAS, GO:0050862=IDA, GO:0050850=IDA, GO:0007165=TAS, GO:0006968=TAS, GO:0007173=TAS, GO:0005887=TAS, GO:0008543=TAS, GO:0042101=IDA, GO:0045087=TAS, GO:0005068=TAS, GO:0001920=IDA, GO:0051051=IDA} T cell receptor signaling pathway, cellular defense response, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, negative regulation of receptor recycling, negative regulation of transport, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of T cell receptor signaling pathway, positive regulation of calcium-mediated signaling, signal transduction T cell receptor complex, integral to plasma membrane, plasma membrane transmembrane receptor protein tyrosine kinase adaptor activity Human TRDMT1 GOC UniProtKB {GO:0006306=GO_REF:0000002, GO:0090116=PMID:9425235, GO:0001975=GO_REF:0000019, GO:0003886=PMID:9425235, GO:0003723=GO_REF:0000037, GO:0008168=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000002, GO:0008033=GO_REF:0000037} O14717 tRNA (cytosine(38)-C(5))-methyltransferase protein 20130413 {GO:0006306=IEA, GO:0090116=TAS, GO:0001975=IEA, GO:0003886=TAS, GO:0003723=IEA, GO:0008168=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0008033=IEA} C-5 methylation of cytosine, DNA methylation, response to amphetamine, tRNA processing nucleus DNA (cytosine-5-)-methyltransferase activity, DNA binding, RNA binding, methyltransferase activity Human TRDN InterPro UniProtKB {GO:0005515=PMID:17526652, GO:0060047=GO_REF:0000019, GO:0005886=PMID:11026130, GO:0051279=PMID:19567751, GO:0005102=GO_REF:0000002, GO:0033018=PMID:17569730, GO:0033017=PMID:11504710, GO:0014808=GO_REF:0000019, GO:0034704=PMID:19403607, GO:0055085=Reactome:REACT_15518, GO:0005891=GO_REF:0000024, GO:0044325=GO_REF:0000024, GO:0060316=PMID:19567751, GO:0014701=PMID:17569730, GO:0010649=PMID:19567751, GO:0005737=PMID:11026130, GO:0006936=PMID:7588753, GO:0034220=Reactome:REACT_25300, GO:0016529=GO_REF:0000002, GO:0060315=PMID:17569730, GO:0016021=GO_REF:0000002, GO:0030674=GO_REF:0000024} Q5SWK9 Triadin protein 20130413 {GO:0005515=IPI, GO:0060047=IEA, GO:0005886=IDA, GO:0051279=TAS, GO:0005102=IEA, GO:0033018=TAS, GO:0033017=TAS, GO:0014808=IEA, GO:0034704=TAS, GO:0055085=TAS, GO:0005891=ISS, GO:0044325=ISS, GO:0060316=TAS, GO:0014701=TAS, GO:0010649=TAS, GO:0005737=IDA, GO:0006936=TAS, GO:0034220=TAS, GO:0016529=IEA, GO:0060315=TAS, GO:0016021=IEA, GO:0030674=ISS} heart contraction, ion transmembrane transport, muscle contraction, negative regulation of ryanodine-sensitive calcium-release channel activity, positive regulation of ryanodine-sensitive calcium-release channel activity, regulation of cell communication by electrical coupling, regulation of release of sequestered calcium ion into cytosol, release of sequestered calcium ion into cytosol by sarcoplasmic reticulum, transmembrane transport calcium channel complex, cytoplasm, integral to membrane, junctional sarcoplasmic reticulum membrane, plasma membrane, sarcoplasmic reticulum, sarcoplasmic reticulum lumen, sarcoplasmic reticulum membrane, voltage-gated calcium channel complex ion channel binding, protein binding, protein binding, bridging, receptor binding Human InterPro:IPR010798 TREH Reactome UniProtKB {GO:0005886=PMID:9427547, GO:0005975=Reactome:REACT_474, GO:0005991=PMID:8773341, GO:0044245=Reactome:REACT_9472, GO:0044281=Reactome:REACT_111217, GO:0004555=PMID:8773341, GO:0046658=PMID:8773341, GO:0005993=PMID:9427547} O43280 Trehalase protein 20130301 {GO:0005886=TAS, GO:0005975=TAS, GO:0005991=NAS, GO:0044245=TAS, GO:0044281=TAS, GO:0004555=IDA, GO:0046658=TAS, GO:0005993=TAS} carbohydrate metabolic process, polysaccharide digestion, small molecule metabolic process, trehalose catabolic process, trehalose metabolic process anchored to plasma membrane, plasma membrane alpha,alpha-trehalase activity Human TREM1 Reactome UniProtKB {GO:0035556=PMID:10799849, GO:0005886=Reactome:REACT_147897, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0006959=PMID:10799849, GO:0004872=PMID:10799849, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0050900=Reactome:REACT_12051} Q9NP99 Triggering receptor expressed on myeloid cells 1 protein 20120221 {GO:0035556=TAS, GO:0005886=TAS, GO:0007596=TAS, GO:0045087=TAS, GO:0006959=TAS, GO:0004872=TAS, GO:0005576=IEA, GO:0016021=IEA, GO:0050900=TAS} blood coagulation, humoral immune response, innate immune response, intracellular signal transduction, leukocyte migration extracellular region, integral to membrane, plasma membrane receptor activity Human TREM2 Reactome UniProtKB {GO:0005886=Reactome:REACT_147879, GO:0007411=Reactome:REACT_18266, GO:0045087=Reactome:REACT_6802, GO:0006959=PMID:10799849, GO:0004872=PMID:10799849, GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q9NZC2 Triggering receptor expressed on myeloid cells 2 protein 20130301 {GO:0005886=TAS, GO:0007411=TAS, GO:0045087=TAS, GO:0006959=TAS, GO:0004872=TAS, GO:0005576=IEA, GO:0016021=IEA} axon guidance, humoral immune response, innate immune response extracellular region, integral to membrane, plasma membrane receptor activity Human TREML1 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0009986=GO_REF:0000019, GO:0045087=PMID:12645956, GO:0031091=GO_REF:0000019, GO:0030168=GO_REF:0000019, GO:0016021=PMID:12645956} Q86YW5 Trem-like transcript 1 protein protein 20080307 {GO:0005886=IEA, GO:0009986=IEA, GO:0045087=NAS, GO:0031091=IEA, GO:0030168=IEA, GO:0016021=NAS} innate immune response, platelet activation cell surface, integral to membrane, plasma membrane, platelet alpha granule Human TRERF1 UniProtKB UniProtKB {GO:0006694=PMID:11349124, GO:0006707=PMID:11349124, GO:0003700=PMID:11349124, GO:0001104=PMID:11349124, GO:0008301=PMID:11349124, GO:0005634=PMID:11349124, GO:0007275=PMID:11349124, GO:0042592=PMID:11349124, GO:0030374=PMID:11349124, GO:0046885=PMID:11349124, GO:0003682=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0045893=PMID:11349124, GO:0008134=PMID:11349124} Q96PN7 Transcriptional-regulating factor 1 protein 20031216 {GO:0006694=NAS, GO:0006707=NAS, GO:0003700=IDA, GO:0001104=NAS, GO:0008301=NAS, GO:0005634=IDA, GO:0007275=NAS, GO:0042592=NAS, GO:0030374=NAS, GO:0046885=NAS, GO:0003682=IEA, GO:0008270=IEA, GO:0045893=IDA, GO:0008134=IPI} cholesterol catabolic process, homeostatic process, multicellular organismal development, positive regulation of transcription, DNA-dependent, regulation of hormone biosynthetic process, steroid biosynthetic process nucleus DNA binding, bending, RNA polymerase II transcription cofactor activity, chromatin binding, ligand-dependent nuclear receptor transcription coactivator activity, sequence-specific DNA binding transcription factor activity, transcription factor binding, zinc ion binding Human TREX1 PINC UniProtKB {GO:0008296=PMID:10393201, GO:0032407=PMID:16713580, GO:0032558=GO_REF:0000019, GO:0008219=GO_REF:0000037, GO:0008408=PMID:11278605, GO:0032405=PMID:16713580, GO:0035458=GO_REF:0000019, GO:0006310=PMID:11278605, GO:0005635=PMID:10391904, GO:0042803=PMID:11278605, GO:0046872=PMID:11278605, GO:0006260=PMID:11278605, GO:0006281=PMID:10393201, GO:0003690=GO_REF:0000019, GO:0003697=PMID:10391904, GO:0008853=GO_REF:0000003, GO:0006298=PMID:11278605} Q9NSU2 Three prime repair exonuclease 1 protein 20050308 {GO:0008296=TAS, GO:0032407=IDA, GO:0032558=IEA, GO:0008219=IEA, GO:0008408=TAS, GO:0032405=IDA, GO:0035458=IEA, GO:0006310=NAS, GO:0005635=NAS, GO:0042803=TAS, GO:0046872=TAS, GO:0006260=NAS, GO:0006281=TAS, GO:0003690=IEA, GO:0003697=TAS, GO:0008853=IEA, GO:0006298=NAS} DNA recombination, DNA repair, DNA replication, cell death, cellular response to interferon-beta, mismatch repair nuclear envelope 3'-5' exonuclease activity, 3'-5'-exodeoxyribonuclease activity, MutLalpha complex binding, MutSalpha complex binding, adenyl deoxyribonucleotide binding, double-stranded DNA binding, exodeoxyribonuclease III activity, metal ion binding, protein homodimerization activity, single-stranded DNA binding Human TREX2 PINC UniProtKB {GO:0005622=GO_REF:0000002, GO:0008296=PMID:10391904, GO:0004527=GO_REF:0000038, GO:0006281=GO_REF:0000037, GO:0008853=GO_REF:0000003, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002} Q9BQ50 Three prime repair exonuclease 2 protein 20050308 {GO:0005622=IEA, GO:0008296=TAS, GO:0004527=IEA, GO:0006281=IEA, GO:0008853=IEA, GO:0005634=IEA, GO:0003676=IEA} DNA repair intracellular, nucleus 3'-5'-exodeoxyribonuclease activity, exodeoxyribonuclease III activity, exonuclease activity, nucleic acid binding Human TRH Reactome UniProtKB {GO:0051412=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0045471=GO_REF:0000019, GO:0009409=GO_REF:0000019, GO:0014050=GO_REF:0000019, GO:0007267=PMID:2126343, GO:0005576=Reactome:REACT_22436, GO:0005634=GO_REF:0000019, GO:0014054=GO_REF:0000019, GO:0009749=GO_REF:0000019, GO:0007165=PMID:2126343, GO:0009755=GO_REF:0000002, GO:0007628=GO_REF:0000019, GO:0042755=GO_REF:0000019, GO:0032024=GO_REF:0000019, GO:0008437=GO_REF:0000019, GO:0005184=GO_REF:0000002, GO:0030141=GO_REF:0000019} P20396 Prothyroliberin protein 20120210 {GO:0051412=IEA, GO:0001666=IEA, GO:0005886=IEA, GO:0045471=IEA, GO:0009409=IEA, GO:0014050=IEA, GO:0007267=TAS, GO:0005576=TAS, GO:0005634=IEA, GO:0014054=IEA, GO:0009749=IEA, GO:0007165=TAS, GO:0009755=IEA, GO:0007628=IEA, GO:0042755=IEA, GO:0032024=IEA, GO:0008437=IEA, GO:0005184=IEA, GO:0030141=IEA} adult walking behavior, cell-cell signaling, eating behavior, hormone-mediated signaling pathway, negative regulation of glutamate secretion, positive regulation of gamma-aminobutyric acid secretion, positive regulation of insulin secretion, response to cold, response to corticosterone stimulus, response to ethanol, response to glucose stimulus, response to hypoxia, signal transduction extracellular region, nucleus, plasma membrane, secretory granule neuropeptide hormone activity, thyrotropin-releasing hormone activity Human TRHDE PINC UniProtKB {GO:0007165=PMID:10491199, GO:0016020=GO_REF:0000002, GO:0005887=PMID:10491199, GO:0004177=GO_REF:0000037, GO:0007267=PMID:10491199, GO:0006508=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0008237=GO_REF:0000037} Q9UKU6 Thyrotropin-releasing hormone-degrading ectoenzyme protein 20030904 {GO:0007165=TAS, GO:0016020=IEA, GO:0005887=TAS, GO:0004177=IEA, GO:0007267=TAS, GO:0006508=IEA, GO:0008270=IEA, GO:0008237=IEA} cell-cell signaling, proteolysis, signal transduction integral to plasma membrane, membrane aminopeptidase activity, metallopeptidase activity, zinc ion binding Human TRHR Reactome UniProtKB {GO:0005886=Reactome:REACT_22436, GO:0007186=PMID:8395824, GO:0005887=PMID:8395824, GO:0004997=GO_REF:0000002} P34981 Thyrotropin-releasing hormone receptor protein 20120210 {GO:0005886=TAS, GO:0007186=TAS, GO:0005887=TAS, GO:0004997=IEA} G-protein coupled receptor signaling pathway integral to plasma membrane, plasma membrane thyrotropin-releasing hormone receptor activity Human TRIAP1 GOC UniProtKB {GO:0005739=PMID:15735003, GO:0005515=PMID:15735003, GO:0043066=PMID:15735003, GO:0048471=GO_REF:0000039, GO:0030330=PMID:15735003, GO:0043154=PMID:15735003, GO:0043027=PMID:15735003, GO:0006977=PMID:15735003} O43715 TP53-regulated inhibitor of apoptosis 1 protein 20130413 {GO:0005739=IDA, GO:0005515=IPI, GO:0043066=IMP, GO:0048471=IEA, GO:0030330=IEP, GO:0043154=IDA, GO:0043027=IDA, GO:0006977=TAS} DNA damage response, signal transduction by p53 class mediator, DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process mitochondrion, perinuclear region of cytoplasm cysteine-type endopeptidase inhibitor activity involved in apoptotic process, protein binding Human TRIB1 BHF-UCL UniProtKB {GO:0032436=PMID:20410507, GO:0007254=PMID:17452330, GO:0031434=PMID:15299019, GO:0005634=PMID:17452330, GO:0048662=PMID:17452330, GO:0005524=PMID:20410507, GO:0043433=PMID:17724128, GO:0014912=PMID:17452330, GO:0005737=PMID:17452330, GO:0004672=PMID:20410507, GO:0043405=PMID:15299019, GO:0032496=PMID:17724128, GO:0004860=PMID:15299019, GO:0006468=PMID:20410507, GO:0055106=PMID:20410507, GO:0031665=PMID:17452330, GO:0006469=PMID:15299019, GO:0031625=PMID:20410507, GO:0008134=PMID:17724128} Q96RU8 Tribbles homolog 1 protein 20100430 {GO:0032436=ISS, GO:0007254=IMP, GO:0031434=IDA, GO:0005634=IDA, GO:0048662=IMP, GO:0005524=TAS, GO:0043433=ISS, GO:0014912=IMP, GO:0005737=IDA, GO:0004672=TAS, GO:0043405=IDA, GO:0032496=ISS, GO:0004860=IMP, GO:0006468=TAS, GO:0055106=ISS, GO:0031665=IMP, GO:0006469=IMP, GO:0031625=ISS, GO:0008134=IPI} JNK cascade, negative regulation of lipopolysaccharide-mediated signaling pathway, negative regulation of protein kinase activity, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of smooth muscle cell migration, negative regulation of smooth muscle cell proliferation, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, protein phosphorylation, regulation of MAP kinase activity, response to lipopolysaccharide cytoplasm, nucleus ATP binding, mitogen-activated protein kinase kinase binding, protein kinase activity, protein kinase inhibitor activity, transcription factor binding, ubiquitin protein ligase binding, ubiquitin-protein ligase regulator activity Human UniProtKB:Q8K4K4 TRIB2 HPA UniProtKB {GO:0045599=PMID:17576771, GO:0005730=GO_REF:0000052, GO:0032436=PMID:20410507, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0004672=GO_REF:0000024, GO:0043405=GO_REF:0000024, GO:0000166=GO_REF:0000024, GO:0004860=GO_REF:0000037, GO:0006468=GO_REF:0000024, GO:0055106=PMID:20410507, GO:0006469=PMID:12791994, GO:0045081=PMID:18643775, GO:0005856=GO_REF:0000039, GO:0031625=PMID:20410507, GO:0008134=PMID:17576771} Q92519 Tribbles homolog 2 protein 20101115 {GO:0045599=ISS, GO:0005730=IDA, GO:0032436=ISS, GO:0005634=IDA, GO:0005524=IEA, GO:0005737=IDA, GO:0004672=ISS, GO:0043405=ISS, GO:0000166=ISS, GO:0004860=IEA, GO:0006468=ISS, GO:0055106=ISS, GO:0006469=NAS, GO:0045081=IMP, GO:0005856=IEA, GO:0031625=ISS, GO:0008134=ISS} negative regulation of fat cell differentiation, negative regulation of interleukin-10 biosynthetic process, negative regulation of protein kinase activity, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, protein phosphorylation, regulation of MAP kinase activity cytoplasm, cytoskeleton, nucleolus, nucleus ATP binding, nucleotide binding, protein kinase activity, protein kinase inhibitor activity, transcription factor binding, ubiquitin protein ligase binding, ubiquitin-protein ligase regulator activity Human TRIB3 HPA UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005515=PMID:12743605, GO:0034976=PMID:15775988, GO:0005886=Reactome:REACT_115815, GO:0045599=PMID:17576771, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0032092=PMID:16794074, GO:0005829=Reactome:REACT_1622, GO:0007173=Reactome:REACT_9417, GO:0043405=PMID:15299019, GO:0016301=PMID:12743605, GO:0055106=PMID:20410507, GO:0051443=PMID:16794074, GO:0044255=Reactome:REACT_22279, GO:0031625=PMID:16794074, GO:0048011=Reactome:REACT_11061, GO:0032869=PMID:12791994, GO:0019901=PMID:12791994, GO:0048015=Reactome:REACT_12464, GO:0003714=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0045717=PMID:16794074, GO:0005524=GO_REF:0000002, GO:0010827=PMID:12791994, GO:0006351=GO_REF:0000037, GO:0004672=GO_REF:0000002, GO:0008543=Reactome:REACT_9470, GO:0070059=PMID:15775988, GO:0045087=Reactome:REACT_6802, GO:0004860=GO_REF:0000037, GO:0006468=GO_REF:0000002, GO:0006469=PMID:12791994, GO:0045892=PMID:15775988} Q96RU7 Tribbles homolog 3 protein 20090616 {GO:0008286=TAS, GO:0005515=IPI, GO:0034976=IDA, GO:0005886=TAS, GO:0045599=ISS, GO:0005634=IDA, GO:0044281=TAS, GO:0032092=ISS, GO:0005829=TAS, GO:0007173=TAS, GO:0043405=IDA, GO:0016301=IDA, GO:0055106=ISS, GO:0051443=ISS, GO:0044255=TAS, GO:0031625=ISS, GO:0048011=TAS, GO:0032869=ISS, GO:0019901=IPI, GO:0048015=TAS, GO:0003714=ISS, GO:0005730=IDA, GO:0045717=ISS, GO:0005524=IEA, GO:0010827=ISS, GO:0006351=IEA, GO:0004672=IEA, GO:0008543=TAS, GO:0070059=IDA, GO:0045087=TAS, GO:0004860=IEA, GO:0006468=IEA, GO:0006469=IDA, GO:0045892=IMP} cellular lipid metabolic process, cellular response to insulin stimulus, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, insulin receptor signaling pathway, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, negative regulation of fat cell differentiation, negative regulation of fatty acid biosynthetic process, negative regulation of protein kinase activity, negative regulation of transcription, DNA-dependent, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, positive regulation of protein binding, positive regulation of ubiquitin-protein ligase activity, protein phosphorylation, regulation of MAP kinase activity, regulation of glucose transport, response to endoplasmic reticulum stress, small molecule metabolic process, transcription, DNA-dependent cytosol, nucleolus, nucleus, plasma membrane ATP binding, kinase activity, protein binding, protein kinase activity, protein kinase binding, protein kinase inhibitor activity, transcription corepressor activity, ubiquitin protein ligase binding, ubiquitin-protein ligase regulator activity NOT Human TRIM10 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000024, GO:0030218=GO_REF:0000019, GO:0008270=GO_REF:0000002} Q9UDY6 Tripartite motif-containing protein 10 protein 20090505 {GO:0008150=ND, GO:0003674=ND, GO:0005737=ISS, GO:0030218=IEA, GO:0008270=IEA} biological_process, erythrocyte differentiation cytoplasm molecular_function, zinc ion binding Human TRIM11 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0004842=GO_REF:0000019, GO:0051607=GO_REF:0000037, GO:0050768=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0045892=GO_REF:0000019, GO:0008134=GO_REF:0000019} Q96F44 E3 ubiquitin-protein ligase TRIM11 protein 20111111 {GO:0005737=IDA, GO:0004842=IEA, GO:0051607=IEA, GO:0050768=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0045892=IEA, GO:0008134=IEA} defense response to virus, negative regulation of neurogenesis, negative regulation of transcription, DNA-dependent cytoplasm, nucleus transcription factor binding, ubiquitin-protein ligase activity, zinc ion binding Human TRIM13 GOC UniProtKB {GO:0005515=PMID:22178386, GO:0004842=PMID:17314412, GO:0030433=PMID:17314412, GO:0009653=PMID:9599022, GO:0097038=PMID:22178386, GO:0051865=PMID:17314412, GO:0007165=PMID:12761501, GO:0005789=PMID:17314412, GO:0008270=GO_REF:0000002, GO:0043161=PMID:17314412, GO:0016021=GO_REF:0000037, GO:0004871=PMID:12761501, GO:0043123=PMID:12761501, GO:0010332=PMID:21333377, GO:0010942=PMID:21333377, GO:0016239=PMID:22178386} O60858 E3 ubiquitin-protein ligase TRIM13 protein 20130413 {GO:0005515=IPI, GO:0004842=IDA, GO:0030433=IDA, GO:0009653=TAS, GO:0097038=IDA, GO:0051865=IDA, GO:0007165=IMP, GO:0005789=IDA, GO:0008270=IEA, GO:0043161=IDA, GO:0016021=IEA, GO:0004871=IMP, GO:0043123=IMP, GO:0010332=IEP, GO:0010942=IDA, GO:0016239=IDA} ER-associated protein catabolic process, anatomical structure morphogenesis, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of cell death, positive regulation of macroautophagy, proteasomal ubiquitin-dependent protein catabolic process, protein autoubiquitination, response to gamma radiation, signal transduction endoplasmic reticulum membrane, integral to membrane, perinuclear endoplasmic reticulum protein binding, signal transducer activity, ubiquitin-protein ligase activity, zinc ion binding Human TRIM14 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0008270=GO_REF:0000002} Q14142 Tripartite motif-containing protein 14 protein 20090505 {GO:0005622=IEA, GO:0003674=ND, GO:0008150=ND, GO:0008270=IEA} biological_process intracellular molecular_function, zinc ion binding Human TRIM15 PINC UniProtKB {GO:0005622=GO_REF:0000002, GO:0007500=PMID:10207104, GO:0008270=GO_REF:0000002} Q9C019 Tripartite motif-containing protein 15 protein 20050308 {GO:0005622=IEA, GO:0007500=TAS, GO:0008270=IEA} mesodermal cell fate determination intracellular zinc ion binding Human TRIM16 HPA UniProtKB {GO:0046683=PMID:16079077, GO:0005515=PMID:16575408, GO:0060416=PMID:11919186, GO:0003677=PMID:16636064, GO:0019966=PMID:16575408, GO:0048386=PMID:16636064, GO:0005737=GO_REF:0000052, GO:0045618=PMID:11919186, GO:0043966=PMID:19147277, GO:0043967=PMID:16636064, GO:0050718=PMID:16575408, GO:0016605=PMID:16636064, GO:0032089=PMID:16575408, GO:0008270=GO_REF:0000002, GO:0032526=PMID:16636064, GO:0045893=PMID:16636064} O95361 Tripartite motif-containing protein 16 protein 20111111 {GO:0046683=IEP, GO:0005515=IPI, GO:0060416=IDA, GO:0003677=IDA, GO:0019966=IPI, GO:0048386=IDA, GO:0005737=IDA, GO:0045618=IDA, GO:0043966=IDA, GO:0043967=IDA, GO:0050718=IMP, GO:0016605=IDA, GO:0032089=IPI, GO:0008270=IEA, GO:0032526=IEP, GO:0045893=IDA} histone H3 acetylation, histone H4 acetylation, positive regulation of interleukin-1 beta secretion, positive regulation of keratinocyte differentiation, positive regulation of retinoic acid receptor signaling pathway, positive regulation of transcription, DNA-dependent, response to growth hormone stimulus, response to organophosphorus, response to retinoic acid PML body, cytoplasm DNA binding, NACHT domain binding, interleukin-1 binding, protein binding, zinc ion binding Human TRIM16L UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q309B1 Tripartite motif-containing protein 16-like protein protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 TRIM17 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0005622=GO_REF:0000002, GO:0004842=PMID:19358823, GO:0008270=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0051865=PMID:19358823} Q9Y577 E3 ubiquitin-protein ligase TRIM17 protein 20130415 {GO:0005515=IPI, GO:0005622=IEA, GO:0004842=IDA, GO:0008270=IEA, GO:0005575=ND, GO:0051865=IDA} protein autoubiquitination cellular_component, intracellular protein binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q9HCM9 TRIM2 UniProtKB UniProtKB {GO:0005515=PMID:21478148, GO:0005622=GO_REF:0000002, GO:0043523=GO_REF:0000024, GO:0005737=PMID:11331580, GO:0004842=GO_REF:0000024, GO:0008270=PMID:11331580} Q9C040 Tripartite motif-containing protein 2 protein 20110831 {GO:0005515=IPI, GO:0005622=IEA, GO:0043523=ISS, GO:0005737=IDA, GO:0004842=ISS, GO:0008270=NAS} regulation of neuron apoptotic process cytoplasm, intracellular protein binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:O88498 TRIM21 HPA UniProtKB {GO:0000209=PMID:16297862, GO:0005515=PMID:11461834, GO:0004842=PMID:16472766, GO:0006513=PMID:16297862, GO:0016567=PMID:16472766, GO:0003723=GO_REF:0000037, GO:0090086=PMID:16472766, GO:0005730=GO_REF:0000052, GO:0032088=PMID:19675099, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0045787=PMID:16880511, GO:0051865=PMID:16880511, GO:0031648=PMID:16880511, GO:0007049=GO_REF:0000037, GO:0070206=PMID:17156811, GO:0005737=GO_REF:0000052, GO:0000932=GO_REF:0000039, GO:0030529=PMID:7832745, GO:0008270=GO_REF:0000002, GO:0019005=PMID:16880511} P19474 E3 ubiquitin-protein ligase TRIM21 protein 20101115 {GO:0000209=IDA, GO:0005515=IPI, GO:0004842=IDA, GO:0006513=IDA, GO:0016567=IDA, GO:0003723=IEA, GO:0090086=IMP, GO:0005730=IDA, GO:0032088=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0045787=IMP, GO:0051865=IDA, GO:0031648=IMP, GO:0007049=IEA, GO:0070206=IDA, GO:0005737=IDA, GO:0000932=IEA, GO:0030529=TAS, GO:0008270=IEA, GO:0019005=IDA} cell cycle, negative regulation of NF-kappaB transcription factor activity, negative regulation of protein deubiquitination, positive regulation of cell cycle, protein autoubiquitination, protein destabilization, protein monoubiquitination, protein polyubiquitination, protein trimerization, protein ubiquitination SCF ubiquitin ligase complex, cytoplasm, cytoplasmic mRNA processing body, nucleolus, nucleus, ribonucleoprotein complex DNA binding, RNA binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human TRIM22 HPA UniProtKB {GO:0006355=PMID:7797467, GO:0005794=GO_REF:0000052, GO:0015030=GO_REF:0000039, GO:0016567=GO_REF:0000041, GO:0003700=PMID:7797467, GO:0003714=PMID:7797467, GO:0016874=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0009615=PMID:7797467, GO:0006351=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0005622=GO_REF:0000002, GO:0070206=PMID:17156811, GO:0005737=GO_REF:0000052, GO:0051607=GO_REF:0000037, GO:0006955=PMID:7797467, GO:0016607=GO_REF:0000039, GO:0019048=GO_REF:0000037, GO:0008270=GO_REF:0000002} Q8IYM9 E3 ubiquitin-protein ligase TRIM22 protein 20080818 {GO:0006355=TAS, GO:0005794=IDA, GO:0015030=IEA, GO:0016567=IEA, GO:0003700=TAS, GO:0003714=TAS, GO:0016874=IEA, GO:0005634=IDA, GO:0009615=TAS, GO:0006351=IEA, GO:0043231=IDA, GO:0005622=IEA, GO:0070206=IDA, GO:0005737=IDA, GO:0051607=IEA, GO:0006955=TAS, GO:0016607=IEA, GO:0019048=IEA, GO:0008270=IEA} defense response to virus, immune response, protein trimerization, protein ubiquitination, regulation of transcription, DNA-dependent, response to virus, transcription, DNA-dependent, virus-host interaction Cajal body, Golgi apparatus, cytoplasm, intracellular, intracellular membrane-bounded organelle, nuclear speck, nucleus ligase activity, sequence-specific DNA binding transcription factor activity, transcription corepressor activity, zinc ion binding Human TRIM23 GOC UniProtKB {GO:0005515=PMID:23088713, GO:0004842=PMID:15684077, GO:0016567=PMID:15684077, GO:0007264=GO_REF:0000002, GO:0003924=PMID:8700863, GO:0005634=GO_REF:0000019, GO:0043085=PMID:8473324, GO:0005765=PMID:9671726, GO:0005525=PMID:8700863, GO:0042802=PMID:22493164, GO:0006184=PMID:8700863, GO:0005737=GO_REF:0000019, GO:0000139=PMID:9671726, GO:0019048=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0019003=PMID:8700863, GO:0008047=PMID:8473324} P36406 E3 ubiquitin-protein ligase TRIM23 protein 20130413 {GO:0005515=IPI, GO:0004842=IDA, GO:0016567=IDA, GO:0007264=IEA, GO:0003924=IDA, GO:0005634=IEA, GO:0043085=TAS, GO:0005765=IDA, GO:0005525=IDA, GO:0042802=IPI, GO:0006184=IDA, GO:0005737=IEA, GO:0000139=IDA, GO:0019048=IEA, GO:0008270=IEA, GO:0019003=IDA, GO:0008047=TAS} GTP catabolic process, positive regulation of catalytic activity, protein ubiquitination, small GTPase mediated signal transduction, virus-host interaction Golgi membrane, cytoplasm, lysosomal membrane, nucleus GDP binding, GTP binding, GTPase activity, enzyme activator activity, identical protein binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human TRIM24 HPA UniProtKB {GO:0005515=PMID:19909775, GO:0004842=PMID:19556538, GO:0016567=PMID:19556538, GO:0008285=GO_REF:0000019, GO:0006366=PMID:9115274, GO:0005634=GO_REF:0000052, GO:0035064=PMID:21164480, GO:0005829=Reactome:REACT_121382, GO:0055074=GO_REF:0000019, GO:0005622=GO_REF:0000002, GO:0034056=PMID:21164480, GO:0002039=PMID:19556538, GO:0030163=PMID:19556538, GO:0046777=GO_REF:0000019, GO:0031647=PMID:19556538, GO:0070577=PMID:21164480, GO:0016922=GO_REF:0000019, GO:0005719=GO_REF:0000019, GO:0003713=PMID:21164480, GO:0005102=PMID:9115274, GO:0071391=PMID:21164480, GO:0042981=PMID:19556538, GO:0043565=GO_REF:0000019, GO:0070562=GO_REF:0000019, GO:0005726=GO_REF:0000019, GO:0004672=GO_REF:0000019, GO:0003682=PMID:21164480, GO:0008270=PMID:21164480, GO:0045893=GO_REF:0000019, GO:0045892=GO_REF:0000019} O15164 Transcription intermediary factor 1-alpha protein 20111111 {GO:0005515=IPI, GO:0004842=IDA, GO:0016567=IDA, GO:0008285=IEA, GO:0006366=TAS, GO:0005634=IDA, GO:0035064=IDA, GO:0005829=TAS, GO:0055074=IEA, GO:0005622=IEA, GO:0034056=IDA, GO:0002039=IPI, GO:0030163=IMP, GO:0046777=IEA, GO:0031647=IMP, GO:0070577=IDA, GO:0016922=IEA, GO:0005719=IEA, GO:0003713=IDA, GO:0005102=TAS, GO:0071391=IDA, GO:0042981=IMP, GO:0043565=IEA, GO:0070562=IEA, GO:0005726=IEA, GO:0004672=IEA, GO:0003682=IDA, GO:0008270=IDA, GO:0045893=IEA, GO:0045892=IEA} calcium ion homeostasis, cellular response to estrogen stimulus, negative regulation of cell proliferation, negative regulation of transcription, DNA-dependent, positive regulation of transcription, DNA-dependent, protein autophosphorylation, protein catabolic process, protein ubiquitination, regulation of apoptotic process, regulation of protein stability, regulation of vitamin D receptor signaling pathway, transcription from RNA polymerase II promoter cytosol, intracellular, nuclear euchromatin, nucleus, perichromatin fibrils chromatin binding, estrogen response element binding, histone acetyl-lysine binding, ligand-dependent nuclear receptor binding, methylated histone residue binding, p53 binding, protein binding, protein kinase activity, receptor binding, sequence-specific DNA binding, transcription coactivator activity, ubiquitin-protein ligase activity, zinc ion binding Human TRIM25 GOC UniProtKB {GO:0005515=PMID:19454348, GO:0006355=PMID:8248217, GO:0004842=GO_REF:0000003, GO:0003700=PMID:8248217, GO:0030054=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005829=Reactome:REACT_25398, GO:0051607=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0019048=GO_REF:0000037, GO:0045087=Reactome:REACT_6802, GO:0008270=GO_REF:0000002, GO:0032480=Reactome:REACT_25271} Q14258 E3 ubiquitin/ISG15 ligase TRIM25 protein 20130413 {GO:0005515=IPI, GO:0006355=TAS, GO:0004842=IEA, GO:0003700=TAS, GO:0030054=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0005829=TAS, GO:0051607=IEA, GO:0005737=IDA, GO:0019048=IEA, GO:0045087=TAS, GO:0008270=IEA, GO:0032480=TAS} defense response to virus, innate immune response, negative regulation of type I interferon production, regulation of transcription, DNA-dependent, virus-host interaction cell junction, cytoplasm, cytosol, nucleolus, nucleus protein binding, sequence-specific DNA binding transcription factor activity, ubiquitin-protein ligase activity, zinc ion binding Human TRIM26 ENSEMBL UniProtKB {GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0003677=PMID:8530076, GO:0046872=PMID:8530076} Q5SPU2 Tripartite motif-containing protein 26 protein 20130413 {GO:0008150=ND, GO:0005737=IEA, GO:0008270=IEA, GO:0005575=ND, GO:0003677=NAS, GO:0046872=NAS} biological_process cellular_component, cytoplasm DNA binding, metal ion binding, zinc ion binding Human Ensembl:ENSMUSP00000114896 TRIM27 GOC UniProtKB {GO:0005515=PMID:22128329, GO:0004842=PMID:22128329, GO:0016567=PMID:22128329, GO:0008283=PMID:2734021, GO:0005634=PMID:17156811, GO:0007283=PMID:3380101, GO:0090281=PMID:22128329, GO:0046872=PMID:3380101, GO:0070206=PMID:17156811, GO:0005737=PMID:17156811, GO:1900041=PMID:22128329, GO:0002820=PMID:22128329, GO:0031965=PMID:10976108, GO:0032720=PMID:22128329, GO:0000122=PMID:10976108, GO:0003676=PMID:3380101, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0072643=PMID:22128329, GO:0016020=PMID:3078962, GO:0005887=PMID:3078962, GO:0045814=PMID:10976108, GO:0016605=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0005654=PMID:10976108, GO:0006469=PMID:22128329, GO:0004714=PMID:3078962} P14373 Zinc finger protein RFP protein 20130413 {GO:0005515=IPI, GO:0004842=IDA, GO:0016567=IDA, GO:0008283=TAS, GO:0005634=IDA, GO:0007283=TAS, GO:0090281=IMP, GO:0046872=TAS, GO:0070206=IDA, GO:0005737=IDA, GO:1900041=IMP, GO:0002820=IMP, GO:0031965=IDA, GO:0032720=IMP, GO:0000122=IDA, GO:0003676=TAS, GO:0003677=IEA, GO:0006351=IEA, GO:0072643=IMP, GO:0016020=TAS, GO:0005887=TAS, GO:0045814=IDA, GO:0016605=IEA, GO:0008270=IEA, GO:0005654=IDA, GO:0006469=IDA, GO:0004714=TAS} cell proliferation, interferon-gamma secretion, negative regulation of adaptive immune response, negative regulation of calcium ion import, negative regulation of gene expression, epigenetic, negative regulation of interleukin-2 secretion, negative regulation of protein kinase activity, negative regulation of transcription from RNA polymerase II promoter, negative regulation of tumor necrosis factor production, protein trimerization, protein ubiquitination, spermatogenesis, transcription, DNA-dependent PML body, cytoplasm, integral to plasma membrane, membrane, nuclear membrane, nucleoplasm, nucleus DNA binding, metal ion binding, nucleic acid binding, protein binding, transmembrane receptor protein tyrosine kinase activity, ubiquitin-protein ligase activity, zinc ion binding Human TRIM28 GOC UniProtKB {GO:0005515=PMID:21888893, GO:0010467=Reactome:REACT_71, GO:0004842=PMID:18082607, GO:0016567=PMID:18082607, GO:0006367=Reactome:REACT_12627, GO:0003700=GO_REF:0000024, GO:0070087=PMID:15882967, GO:0005634=GO_REF:0000024, GO:0045739=PMID:17178852, GO:0001837=GO_REF:0000024, GO:0051259=PMID:17512541, GO:0005622=GO_REF:0000002, GO:0060669=GO_REF:0000019, GO:0060028=GO_REF:0000019, GO:0046777=GO_REF:0000019, GO:0031625=PMID:18082607, GO:0005719=GO_REF:0000019, GO:0003714=PMID:8769649, GO:0016925=PMID:18082607, GO:0003713=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0003677=PMID:9016654, GO:0043565=GO_REF:0000024, GO:0005720=GO_REF:0000019, GO:0004672=GO_REF:0000019, GO:0006281=PMID:17178852, GO:0005654=Reactome:REACT_27218, GO:0008270=PMID:11226167, GO:0045893=GO_REF:0000024, GO:0045892=PMID:9016654} Q13263 Transcription intermediary factor 1-beta protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0004842=IDA, GO:0016567=IDA, GO:0006367=TAS, GO:0003700=ISS, GO:0070087=IPI, GO:0005634=ISS, GO:0045739=IDA, GO:0001837=ISS, GO:0051259=IDA, GO:0005622=IEA, GO:0060669=IEA, GO:0060028=IEA, GO:0046777=IEA, GO:0031625=IDA, GO:0005719=IEA, GO:0003714=IDA, GO:0016925=IDA, GO:0003713=IEA, GO:0000122=IEA, GO:0003677=IDA, GO:0043565=ISS, GO:0005720=IEA, GO:0004672=IEA, GO:0006281=IDA, GO:0005654=TAS, GO:0008270=IDA, GO:0045893=ISS, GO:0045892=IDA} DNA repair, convergent extension involved in axis elongation, embryonic placenta morphogenesis, epithelial to mesenchymal transition, gene expression, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of DNA repair, positive regulation of transcription, DNA-dependent, protein autophosphorylation, protein oligomerization, protein sumoylation, protein ubiquitination, transcription initiation from RNA polymerase II promoter intracellular, nuclear euchromatin, nuclear heterochromatin, nucleoplasm, nucleus DNA binding, chromo shadow domain binding, protein binding, protein kinase activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, transcription corepressor activity, ubiquitin protein ligase binding, ubiquitin-protein ligase activity, zinc ion binding Human TRIM29 IntAct UniProtKB {GO:0005515=PMID:19249679, GO:0002039=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0003700=PMID:8188213, GO:0006366=PMID:8188213, GO:0008270=GO_REF:0000002, GO:0000122=GO_REF:0000019, GO:1900181=GO_REF:0000019} Q14134 Tripartite motif-containing protein 29 protein 20130415 {GO:0005515=IPI, GO:0002039=IEA, GO:0005737=IEA, GO:0003700=TAS, GO:0006366=TAS, GO:0008270=IEA, GO:0000122=IEA, GO:1900181=IEA} negative regulation of protein localization to nucleus, negative regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter cytoplasm p53 binding, protein binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB:P49841 TRIM3 PINC UniProtKB {GO:0005515=PMID:19460345, GO:0005622=GO_REF:0000002, GO:0005737=PMID:10391919, GO:0008270=GO_REF:0000002, GO:0008022=PMID:10391919, GO:0015031=GO_REF:0000037, GO:0005769=GO_REF:0000039, GO:0007399=PMID:10391919} O75382 Tripartite motif-containing protein 3 protein 20030904 {GO:0005515=IPI, GO:0005622=IEA, GO:0005737=TAS, GO:0008270=IEA, GO:0008022=TAS, GO:0015031=IEA, GO:0005769=IEA, GO:0007399=TAS} nervous system development, protein transport cytoplasm, early endosome, intracellular protein C-terminus binding, protein binding, zinc ion binding Human TRIM31 UniPathway UniProtKB {GO:0005739=GO_REF:0000039, GO:0005622=GO_REF:0000002, GO:0016567=GO_REF:0000041, GO:0016874=GO_REF:0000037, GO:0008270=GO_REF:0000002} Q9BZY9 E3 ubiquitin-protein ligase TRIM31 protein 20130413 {GO:0005739=IEA, GO:0005622=IEA, GO:0016567=IEA, GO:0016874=IEA, GO:0008270=IEA} protein ubiquitination intracellular, mitochondrion ligase activity, zinc ion binding Human UniPathway:UPA00143 TRIM32 ENSEMBL UniProtKB {GO:0005515=PMID:18632609, GO:0005863=GO_REF:0000019, GO:0043130=PMID:19349376, GO:0045732=GO_REF:0000019, GO:0004842=GO_REF:0000019, GO:0016567=PMID:16816390, GO:0030307=PMID:18632609, GO:0003723=GO_REF:0000019, GO:0048147=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0043621=PMID:19349376, GO:2000147=GO_REF:0000019, GO:0005737=PMID:19349376, GO:0051092=GO_REF:0000019, GO:0042787=PMID:19349376, GO:0050769=GO_REF:0000019, GO:0045444=GO_REF:0000019, GO:0009411=GO_REF:0000019, GO:0000209=PMID:18632609, GO:0043066=PMID:18632609, GO:0030335=PMID:18632609, GO:0003713=PMID:7778269, GO:0045787=PMID:18632609, GO:0030957=PMID:16175175, GO:0045862=PMID:18632609, GO:0045666=GO_REF:0000019, GO:0045087=PMID:16175175, GO:0017022=GO_REF:0000019, GO:0031369=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0034612=GO_REF:0000019} Q5JVY0 E3 ubiquitin-protein ligase TRIM32 protein 20130413 {GO:0005515=IPI, GO:0005863=IEA, GO:0043130=IDA, GO:0045732=IEA, GO:0004842=IEA, GO:0016567=IDA, GO:0030307=IDA, GO:0003723=IEA, GO:0048147=IEA, GO:0005634=IEA, GO:0043621=IDA, GO:2000147=IEA, GO:0005737=IDA, GO:0051092=IEA, GO:0042787=IMP, GO:0050769=IEA, GO:0045444=IEA, GO:0009411=IEA, GO:0000209=IDA, GO:0043066=IDA, GO:0030335=IDA, GO:0003713=TAS, GO:0045787=IDA, GO:0030957=TAS, GO:0045862=IDA, GO:0045666=IEA, GO:0045087=TAS, GO:0017022=IEA, GO:0031369=IEA, GO:0008270=IEA, GO:0034612=IEA} fat cell differentiation, innate immune response, negative regulation of apoptotic process, negative regulation of fibroblast proliferation, positive regulation of NF-kappaB transcription factor activity, positive regulation of cell cycle, positive regulation of cell growth, positive regulation of cell migration, positive regulation of cell motility, positive regulation of neurogenesis, positive regulation of neuron differentiation, positive regulation of protein catabolic process, positive regulation of proteolysis, protein polyubiquitination, protein ubiquitination, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, response to UV, response to tumor necrosis factor cytoplasm, nucleus, striated muscle myosin thick filament RNA binding, Tat protein binding, myosin binding, protein binding, protein self-association, transcription coactivator activity, translation initiation factor binding, ubiquitin binding, ubiquitin-protein ligase activity, zinc ion binding Human Ensembl:ENSMUSP00000062277 TRIM33 HPA UniProtKB {GO:0005515=PMID:20603019, GO:0010467=Reactome:REACT_71, GO:0004842=Reactome:REACT_120873, GO:0006367=Reactome:REACT_12627, GO:0016567=PMID:19135894, GO:0070410=PMID:19135894, GO:0005730=GO_REF:0000052, GO:0070412=PMID:19135894, GO:0005634=GO_REF:0000052, GO:0000122=Reactome:REACT_121111, GO:0003677=GO_REF:0000037, GO:0006351=Reactome:REACT_121061, GO:0043231=GO_REF:0000052, GO:0030514=PMID:19135894, GO:0008270=GO_REF:0000029, GO:0005654=Reactome:REACT_121012, GO:0007179=Reactome:REACT_6844, GO:0017015=PMID:19135894, GO:0045892=PMID:10022127} Q9UPN9 E3 ubiquitin-protein ligase TRIM33 protein 20101115 {GO:0005515=IPI, GO:0010467=TAS, GO:0004842=TAS, GO:0006367=TAS, GO:0016567=IDA, GO:0070410=IPI, GO:0005730=IDA, GO:0070412=IPI, GO:0005634=IDA, GO:0000122=TAS, GO:0003677=IEA, GO:0006351=TAS, GO:0043231=IDA, GO:0030514=IDA, GO:0008270=NAS, GO:0005654=TAS, GO:0007179=TAS, GO:0017015=IDA, GO:0045892=NAS} gene expression, negative regulation of BMP signaling pathway, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, protein ubiquitination, regulation of transforming growth factor beta receptor signaling pathway, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway intracellular membrane-bounded organelle, nucleolus, nucleoplasm, nucleus DNA binding, R-SMAD binding, co-SMAD binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human TRIM34 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0070206=PMID:17156811, GO:0005737=PMID:17156811, GO:0008270=GO_REF:0000002} Q9BYJ4 Tripartite motif-containing protein 34 protein 20090505 {GO:0003674=ND, GO:0070206=IDA, GO:0005737=IDA, GO:0008270=IEA} protein trimerization cytoplasm molecular_function, zinc ion binding Human TRIM35 HPA UniProtKB {GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0043065=PMID:14662771, GO:0008285=GO_REF:0000019, GO:0045930=PMID:14662771, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0006917=GO_REF:0000024} Q9UPQ4 Tripartite motif-containing protein 35 protein 20100326 {GO:0003674=ND, GO:0005737=IDA, GO:0043065=IDA, GO:0008285=IEA, GO:0045930=IDA, GO:0005730=IDA, GO:0006915=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0006917=ISS} apoptotic process, induction of apoptosis, negative regulation of cell proliferation, negative regulation of mitotic cell cycle, positive regulation of apoptotic process cytoplasm, nucleolus, nucleus molecular_function, zinc ion binding Human TRIM36 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0001669=GO_REF:0000039, GO:0016874=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0007340=GO_REF:0000019, GO:0005856=GO_REF:0000039} Q9NQ86 E3 ubiquitin-protein ligase TRIM36 protein 20130413 {GO:0005622=IEA, GO:0001669=IEA, GO:0016874=IEA, GO:0008270=IEA, GO:0007340=IEA, GO:0005856=IEA} acrosome reaction acrosomal vesicle, cytoskeleton, intracellular ligase activity, zinc ion binding Human UniProtKB-SubCell:SL-0090 TRIM37 IntAct UniProtKB {GO:0005515=PMID:19447967, GO:0005164=PMID:11279055, GO:0048471=GO_REF:0000039, GO:0004842=PMID:15885686, GO:0016235=PMID:15885686, GO:0032088=PMID:11279055, GO:0042803=PMID:11279055, GO:0005829=PMID:11279055, GO:0051865=PMID:15885686, GO:0005622=GO_REF:0000002, GO:0070842=PMID:15885686, GO:0008270=GO_REF:0000002, GO:0031625=PMID:11279055, GO:0005777=PMID:11938494} O94972 E3 ubiquitin-protein ligase TRIM37 protein 20130415 {GO:0005515=IPI, GO:0005164=IPI, GO:0048471=IEA, GO:0004842=IDA, GO:0016235=IDA, GO:0032088=IDA, GO:0042803=IDA, GO:0005829=IDA, GO:0051865=IDA, GO:0005622=IEA, GO:0070842=IDA, GO:0008270=IEA, GO:0031625=IPI, GO:0005777=IDA} aggresome assembly, negative regulation of NF-kappaB transcription factor activity, protein autoubiquitination aggresome, cytosol, intracellular, perinuclear region of cytoplasm, peroxisome protein binding, protein homodimerization activity, tumor necrosis factor receptor binding, ubiquitin protein ligase binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:O43663 TRIM38 GOC UniProtKB {GO:0005622=GO_REF:0000002, GO:0007165=PMID:12761501, GO:0008270=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0004871=PMID:12761501, GO:0043123=PMID:12761501} O00635 Tripartite motif-containing protein 38 protein 20130413 {GO:0005622=IEA, GO:0007165=IMP, GO:0008270=IEA, GO:0005575=ND, GO:0004871=IMP, GO:0043123=IMP} positive regulation of I-kappaB kinase/NF-kappaB cascade, signal transduction cellular_component, intracellular signal transducer activity, zinc ion binding Human TRIM39 IntAct UniProtKB {GO:0005515=PMID:22493164, GO:0005739=GO_REF:0000039, GO:0005622=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0016567=GO_REF:0000041, GO:0016874=GO_REF:0000037, GO:0006915=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0042802=PMID:22493164, GO:0005829=GO_REF:0000039} Q9HCM9 E3 ubiquitin-protein ligase TRIM39 protein 20130415 {GO:0005515=IPI, GO:0005739=IEA, GO:0005622=IEA, GO:0003674=ND, GO:0008150=ND, GO:0016567=IEA, GO:0016874=IEA, GO:0006915=IEA, GO:0008270=IEA, GO:0005575=ND, GO:0042802=IPI, GO:0005829=IEA} apoptotic process, biological_process, protein ubiquitination cellular_component, cytosol, intracellular, mitochondrion identical protein binding, ligase activity, molecular_function, protein binding, zinc ion binding Human UniProtKB:Q9HCM9 TRIM4 HPA UniProtKB {GO:0005622=GO_REF:0000002, GO:0070206=PMID:17156811, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0008270=GO_REF:0000002} Q9C037 Tripartite motif-containing protein 4 protein 20101115 {GO:0005622=IEA, GO:0070206=IDA, GO:0005737=IDA, GO:0005886=IDA, GO:0008270=IEA} protein trimerization cytoplasm, intracellular, plasma membrane zinc ion binding Human TRIM40 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q6P9F5 Tripartite motif-containing protein 40 protein 20130413 {GO:0005622=IEA, GO:0008270=IEA} intracellular zinc ion binding Human InterPro:IPR000315|InterPro:IPR001841 TRIM41 UniPathway UniProtKB {GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0016567=GO_REF:0000041, GO:0016874=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002} Q8WV44 E3 ubiquitin-protein ligase TRIM41 protein 20130413 {GO:0005622=IEA, GO:0005737=IEA, GO:0016567=IEA, GO:0016874=IEA, GO:0005634=IEA, GO:0008270=IEA} protein ubiquitination cytoplasm, intracellular, nucleus ligase activity, zinc ion binding Human UniPathway:UPA00143 TRIM42 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q8IWZ5 Tripartite motif-containing protein 42 protein 20130413 {GO:0005622=IEA, GO:0008270=IEA} intracellular zinc ion binding Human InterPro:IPR000315|InterPro:IPR001841 TRIM43 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q96BQ3 Tripartite motif-containing protein 43 protein 20130413 {GO:0005622=IEA, GO:0008270=IEA} intracellular zinc ion binding Human InterPro:IPR000315|InterPro:IPR001841 TRIM44 UniProtKB UniProtKB {GO:0005515=PMID:19358823, GO:0005622=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q96DX7 Tripartite motif-containing protein 44 protein 20120708 {GO:0005515=IPI, GO:0005622=IEA, GO:0008270=IEA} intracellular protein binding, zinc ion binding Human UniProtKB:Q9Y577 TRIM45 HPA UniProtKB {GO:0005737=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002} Q9H8W5 Tripartite motif-containing protein 45 protein 20111111 {GO:0005737=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA} cytoplasm, nucleolus, nucleus zinc ion binding NOT Human TRIM46 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q7Z4K8 Tripartite motif-containing protein 46 protein 20130413 {GO:0005622=IEA, GO:0008270=IEA} intracellular zinc ion binding Human InterPro:IPR000315|InterPro:IPR001841 TRIM47 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002} Q96LD4 Tripartite motif-containing protein 47 protein 20130413 {GO:0005737=IEA, GO:0005634=IEA, GO:0008270=IEA} cytoplasm, nucleus zinc ion binding Human UniProtKB-SubCell:SL-0086 TRIM48 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q8IWZ4 Tripartite motif-containing protein 48 protein 20130413 {GO:0005622=IEA, GO:0008270=IEA} intracellular zinc ion binding Human InterPro:IPR000315|InterPro:IPR001841 TRIM49 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0008270=GO_REF:0000002} P0CI25 Tripartite motif-containing protein 49 protein 20130413 {GO:0005622=IEA, GO:0008270=IEA} intracellular zinc ion binding Human InterPro:IPR000315|InterPro:IPR001841 TRIM5 GOC UniProtKB {GO:0005515=PMID:22493164, GO:0004842=PMID:21512573, GO:0005794=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0002218=PMID:21512573, GO:0042803=PMID:11331580, GO:0042802=PMID:22493164, GO:0005622=GO_REF:0000002, GO:0002221=PMID:21512573, GO:0070534=PMID:21512573, GO:0005737=GO_REF:0000052, GO:0051607=PMID:22291694, GO:0051092=PMID:21512573, GO:0000932=PMID:20357094, GO:0019048=GO_REF:0000037, GO:0045087=GO_REF:0000037, GO:0031664=PMID:21512573, GO:0008270=GO_REF:0000002, GO:0043410=PMID:21512573, GO:0043123=PMID:21512573, GO:0008329=PMID:21512573} Q9C035 Tripartite motif-containing protein 5 protein 20130413 {GO:0005515=IPI, GO:0004842=IDA, GO:0005794=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0002218=IDA, GO:0042803=IPI, GO:0042802=IPI, GO:0005622=IEA, GO:0002221=IDA, GO:0070534=IDA, GO:0005737=IDA, GO:0051607=TAS, GO:0051092=IMP, GO:0000932=IDA, GO:0019048=IEA, GO:0045087=IEA, GO:0031664=IMP, GO:0008270=IEA, GO:0043410=IMP, GO:0043123=IMP, GO:0008329=IDA} activation of innate immune response, defense response to virus, innate immune response, pattern recognition receptor signaling pathway, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of MAPK cascade, positive regulation of NF-kappaB transcription factor activity, protein K63-linked ubiquitination, regulation of lipopolysaccharide-mediated signaling pathway, virus-host interaction Golgi apparatus, cytoplasm, cytoplasmic mRNA processing body, intracellular, nucleolus, nucleus identical protein binding, pattern recognition receptor activity, protein binding, protein homodimerization activity, ubiquitin-protein ligase activity, zinc ion binding Human TRIM50 HPA UniProtKB {GO:0005737=GO_REF:0000039, GO:0016874=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0043231=GO_REF:0000052} Q86XT4 E3 ubiquitin-protein ligase TRIM50 protein 20100326 {GO:0005737=IEA, GO:0016874=IEA, GO:0008270=IEA, GO:0043231=IDA} cytoplasm, intracellular membrane-bounded organelle ligase activity, zinc ion binding Human TRIM52 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q96A61 Tripartite motif-containing protein 52 protein 20130413 {GO:0005622=IEA, GO:0008270=IEA} intracellular zinc ion binding Human InterPro:IPR000315|InterPro:IPR001841 TRIM54 UniProtKB UniProtKB {GO:0008017=GO_REF:0000019, GO:0007165=PMID:11243782, GO:0030018=GO_REF:0000039, GO:0005875=GO_REF:0000019, GO:0005874=PMID:11243782, GO:0007026=PMID:11243782, GO:0008270=PMID:11243782, GO:0007275=GO_REF:0000037, GO:0004871=PMID:11243782, GO:0007017=PMID:11243782, GO:0030154=GO_REF:0000037} Q9BYV2 Tripartite motif-containing protein 54 protein 20061106 {GO:0008017=IEA, GO:0007165=NAS, GO:0030018=IEA, GO:0005875=IEA, GO:0005874=NAS, GO:0007026=NAS, GO:0008270=NAS, GO:0007275=IEA, GO:0004871=NAS, GO:0007017=NAS, GO:0030154=IEA} cell differentiation, microtubule-based process, multicellular organismal development, negative regulation of microtubule depolymerization, signal transduction Z disc, microtubule, microtubule associated complex microtubule binding, signal transducer activity, zinc ion binding Human TRIM55 IntAct UniProtKB {GO:0007165=PMID:11243782, GO:0005737=GO_REF:0000039, GO:0005874=PMID:11243782, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0004871=PMID:11243782, GO:0042802=PMID:22493164} Q9BYV6 Tripartite motif-containing protein 55 protein 20130415 {GO:0007165=NAS, GO:0005737=IEA, GO:0005874=NAS, GO:0005634=IEA, GO:0008270=IEA, GO:0004871=NAS, GO:0042802=IPI} signal transduction cytoplasm, microtubule, nucleus identical protein binding, signal transducer activity, zinc ion binding Human UniProtKB:Q9BYV6 TRIM56 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0051607=GO_REF:0000024, GO:0070534=GO_REF:0000024, GO:0004842=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0034340=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0032608=GO_REF:0000024} Q9BRZ2 E3 ubiquitin-protein ligase TRIM56 protein 20101217 {GO:0005622=IEA, GO:0051607=ISS, GO:0070534=ISS, GO:0004842=ISS, GO:0005737=ISS, GO:0034340=ISS, GO:0008270=IEA, GO:0032608=ISS} defense response to virus, interferon-beta production, protein K63-linked ubiquitination, response to type I interferon cytoplasm, intracellular ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q80VI1 TRIM58 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q8NG06 Tripartite motif-containing protein 58 protein 20130413 {GO:0005622=IEA, GO:0008270=IEA} intracellular zinc ion binding Human InterPro:IPR000315|InterPro:IPR001841 TRIM59 MGI UniProtKB {GO:0005622=GO_REF:0000002, GO:0004842=GO_REF:0000019, GO:0005783=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0043124=PMID:22588174} Q8IWR1 Tripartite motif-containing protein 59 protein 20121001 {GO:0005622=IEA, GO:0004842=IEA, GO:0005783=IEA, GO:0008270=IEA, GO:0016021=IEA, GO:0043124=IMP} negative regulation of I-kappaB kinase/NF-kappaB cascade endoplasmic reticulum, integral to membrane, intracellular ubiquitin-protein ligase activity, zinc ion binding Human TRIM6 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0070206=PMID:17156811, GO:0005737=PMID:17156811, GO:0008270=GO_REF:0000002} Q9C030 Tripartite motif-containing protein 6 protein 20090505 {GO:0005622=IEA, GO:0003674=ND, GO:0070206=IDA, GO:0005737=IDA, GO:0008270=IEA} protein trimerization cytoplasm, intracellular molecular_function, zinc ion binding Human TRIM62 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q9BVG3 Tripartite motif-containing protein 62 protein 20130413 {GO:0005622=IEA, GO:0008270=IEA} intracellular zinc ion binding Human InterPro:IPR000315|InterPro:IPR001841 TRIM63 UniProtKB UniProtKB {GO:0004842=GO_REF:0000019, GO:0030018=GO_REF:0000039, GO:0005874=PMID:11243782, GO:0014732=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0031430=GO_REF:0000039, GO:0031432=PMID:11927605, GO:0007165=PMID:11243782, GO:0005737=PMID:11243782, GO:0006936=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0043161=GO_REF:0000019, GO:0004871=PMID:11243782, GO:0070555=GO_REF:0000019} Q969Q1 E3 ubiquitin-protein ligase TRIM63 protein 20021105 {GO:0004842=IEA, GO:0030018=IEA, GO:0005874=NAS, GO:0014732=IEA, GO:0051384=IEA, GO:0005634=IEA, GO:0031430=IEA, GO:0031432=IDA, GO:0007165=NAS, GO:0005737=NAS, GO:0006936=IEA, GO:0008270=IEA, GO:0043161=IEA, GO:0004871=NAS, GO:0070555=IEA} muscle contraction, proteasomal ubiquitin-dependent protein catabolic process, response to glucocorticoid stimulus, response to interleukin-1, signal transduction, skeletal muscle atrophy M band, Z disc, cytoplasm, microtubule, nucleus signal transducer activity, titin binding, ubiquitin-protein ligase activity, zinc ion binding Human TRIM64C InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0008270=GO_REF:0000002} E9PII4 Putative tripartite motif-containing protein 64C protein 20130413 {GO:0005622=IEA, GO:0008270=IEA} intracellular zinc ion binding Human InterPro:IPR000315|InterPro:IPR001841 TRIM65 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q6PJ69 Tripartite motif-containing protein 65 protein 20130413 {GO:0005622=IEA, GO:0008270=IEA} intracellular zinc ion binding Human InterPro:IPR000315|InterPro:IPR001841 TRIM68 HPA UniProtKB {GO:0035035=PMID:18451177, GO:0005622=GO_REF:0000002, GO:0004842=PMID:18451177, GO:0048471=GO_REF:0000039, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0060765=PMID:18451177, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0050681=PMID:18451177, GO:0051865=PMID:18451177} Q6AZZ1 E3 ubiquitin-protein ligase TRIM68 protein 20100326 {GO:0035035=IPI, GO:0005622=IEA, GO:0004842=IDA, GO:0048471=IEA, GO:0005737=IDA, GO:0005794=IDA, GO:0060765=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0050681=IPI, GO:0051865=IDA} protein autoubiquitination, regulation of androgen receptor signaling pathway Golgi apparatus, cytoplasm, intracellular, nucleolus, nucleus, perinuclear region of cytoplasm androgen receptor binding, histone acetyltransferase binding, ubiquitin-protein ligase activity, zinc ion binding Human TRIM69 UniProtKB UniProtKB {GO:0004842=PMID:23131556, GO:0005737=PMID:23131556, GO:0016607=PMID:23131556, GO:0006915=GO_REF:0000037, GO:0005634=PMID:23131556, GO:0008270=GO_REF:0000002} Q86WT6 E3 ubiquitin-protein ligase TRIM69 protein 20121211 {GO:0004842=IDA, GO:0005737=IDA, GO:0016607=IDA, GO:0006915=IEA, GO:0005634=IDA, GO:0008270=IEA} apoptotic process cytoplasm, nuclear speck, nucleus ubiquitin-protein ligase activity, zinc ion binding Human TRIM7 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0043231=GO_REF:0000052} Q9C029 Tripartite motif-containing protein 7 protein 20110516 {GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0043231=IDA} cytoplasm, intracellular membrane-bounded organelle, nucleolus, nucleus zinc ion binding Human TRIM72 UniProtKB UniProtKB {GO:0042383=GO_REF:0000024, GO:0007517=GO_REF:0000024, GO:0001786=GO_REF:0000024, GO:0001778=GO_REF:0000024, GO:0051260=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0006887=GO_REF:0000037, GO:0003012=GO_REF:0000024, GO:0030659=GO_REF:0000024} Q6ZMU5 Tripartite motif-containing protein 72 protein 20090723 {GO:0042383=ISS, GO:0007517=ISS, GO:0001786=ISS, GO:0001778=ISS, GO:0051260=ISS, GO:0008270=IEA, GO:0006887=IEA, GO:0003012=ISS, GO:0030659=ISS} exocytosis, muscle organ development, muscle system process, plasma membrane repair, protein homooligomerization cytoplasmic vesicle membrane, sarcolemma phosphatidylserine binding, zinc ion binding Human UniProtKB:Q1XH17 TRIM73 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q86UV7 Tripartite motif-containing protein 73 protein 20130413 {GO:0005622=IEA, GO:0008270=IEA} intracellular zinc ion binding Human InterPro:IPR000315|InterPro:IPR001841 TRIM74 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q86UV6 Tripartite motif-containing protein 74 protein 20130413 {GO:0005622=IEA, GO:0008270=IEA} intracellular zinc ion binding Human InterPro:IPR000315|InterPro:IPR001841 TRIM8 HPA UniProtKB {GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0016567=GO_REF:0000041, GO:0016605=PMID:11331580, GO:0016874=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=PMID:11118312, GO:0042803=PMID:11331580, GO:0042802=PMID:22493164, GO:0043231=GO_REF:0000052} Q9BZR9 Probable E3 ubiquitin-protein ligase TRIM8 protein 20101115 {GO:0008150=ND, GO:0005737=IDA, GO:0016567=IEA, GO:0016605=IDA, GO:0016874=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=NAS, GO:0042803=IPI, GO:0042802=IPI, GO:0043231=IDA} biological_process, protein ubiquitination PML body, cytoplasm, intracellular membrane-bounded organelle, nucleolus, nucleus identical protein binding, ligase activity, protein homodimerization activity, zinc ion binding Human TRIM9 UniProtKB UniProtKB {GO:0004842=PMID:20085810, GO:0030054=GO_REF:0000037, GO:0016079=GO_REF:0000019, GO:0042803=PMID:11331580, GO:0030425=PMID:20085810, GO:0008021=GO_REF:0000039, GO:0035544=GO_REF:0000019, GO:0005737=PMID:20085810, GO:0045955=GO_REF:0000019, GO:0000149=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0043161=PMID:20085810, GO:0005856=GO_REF:0000039} Q9C026 E3 ubiquitin-protein ligase TRIM9 protein 20100602 {GO:0004842=IDA, GO:0030054=IEA, GO:0016079=IEA, GO:0042803=IPI, GO:0030425=IDA, GO:0008021=IEA, GO:0035544=IEA, GO:0005737=IDA, GO:0045955=IEA, GO:0000149=IEA, GO:0008270=IEA, GO:0043161=IDA, GO:0005856=IEA} negative regulation of SNARE complex assembly, negative regulation of calcium ion-dependent exocytosis, proteasomal ubiquitin-dependent protein catabolic process, synaptic vesicle exocytosis cell junction, cytoplasm, cytoskeleton, dendrite, synaptic vesicle SNARE binding, protein homodimerization activity, ubiquitin-protein ligase activity, zinc ion binding Human TRIML1 UniPathway UniProtKB {GO:0016567=GO_REF:0000041, GO:0016874=GO_REF:0000037, GO:0007275=GO_REF:0000019, GO:0008270=GO_REF:0000002} Q8N9V2 Probable E3 ubiquitin-protein ligase TRIML1 protein 20130413 {GO:0016567=IEA, GO:0016874=IEA, GO:0007275=IEA, GO:0008270=IEA} multicellular organismal development, protein ubiquitination ligase activity, zinc ion binding Human UniPathway:UPA00143 TRIML2 UniPathway UniProtKB {GO:0005622=GO_REF:0000002, GO:0016567=GO_REF:0000041, GO:0016874=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0032526=GO_REF:0000019} Q8N7C3 Probable E3 ubiquitin-protein ligase TRIML2 protein 20130413 {GO:0005622=IEA, GO:0016567=IEA, GO:0016874=IEA, GO:0008270=IEA, GO:0032526=IEA} protein ubiquitination, response to retinoic acid intracellular ligase activity, zinc ion binding Human UniPathway:UPA00143 TRIO IntAct UniProtKB {GO:0005515=PMID:17043677, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0035023=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0006915=Reactome:REACT_13638, GO:0097190=Reactome:REACT_13720, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_22281, GO:0005622=GO_REF:0000002, GO:0005085=PMID:8643598, GO:0005543=GO_REF:0000002, GO:0004674=GO_REF:0000037, GO:0007411=Reactome:REACT_18266, GO:0007185=PMID:8643598, GO:0005089=GO_REF:0000002} O75962 Triple functional domain protein protein 20130415 {GO:0005515=IPI, GO:0051056=TAS, GO:0048011=TAS, GO:0035023=IEA, GO:0007264=TAS, GO:0006915=TAS, GO:0097190=TAS, GO:0005524=IEA, GO:0005829=TAS, GO:0005622=IEA, GO:0005085=TAS, GO:0005543=IEA, GO:0004674=IEA, GO:0007411=TAS, GO:0007185=TAS, GO:0005089=IEA} apoptotic process, apoptotic signaling pathway, axon guidance, neurotrophin TRK receptor signaling pathway, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, small GTPase mediated signal transduction, transmembrane receptor protein tyrosine phosphatase signaling pathway cytosol, intracellular ATP binding, Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, phospholipid binding, protein binding, protein serine/threonine kinase activity Human UniProtKB:Q9NRI5 TRIOBP HPA UniProtKB {GO:0030047=PMID:11148140, GO:0051016=PMID:11148140, GO:0005737=GO_REF:0000052, GO:0051015=PMID:11148140, GO:0005543=GO_REF:0000002, GO:1900026=PMID:11148140, GO:0005634=GO_REF:0000039, GO:0017049=PMID:11148140, GO:0015629=PMID:11148140, GO:0045159=PMID:11148140, GO:0031625=PMID:18194665} Q9H2D6 TRIO and F-actin-binding protein protein 20100326 {GO:0030047=NAS, GO:0051016=NAS, GO:0005737=IDA, GO:0051015=IDA, GO:0005543=IEA, GO:1900026=IDA, GO:0005634=IEA, GO:0017049=NAS, GO:0015629=IDA, GO:0045159=NAS, GO:0031625=IPI} actin modification, barbed-end actin filament capping, positive regulation of substrate adhesion-dependent cell spreading actin cytoskeleton, cytoplasm, nucleus GTP-Rho binding, actin filament binding, myosin II binding, phospholipid binding, ubiquitin protein ligase binding Human TRIP10 IntAct UniProtKB {GO:0051056=Reactome:REACT_11051, GO:0048471=GO_REF:0000039, GO:0005794=GO_REF:0000039, GO:0030036=PMID:9210375, GO:0007264=Reactome:REACT_11044, GO:0001891=GO_REF:0000039, GO:0042995=GO_REF:0000037, GO:0005764=GO_REF:0000039, GO:0042802=PMID:18329367, GO:0005829=Reactome:REACT_9982, GO:0006897=GO_REF:0000037, GO:0008289=GO_REF:0000037, GO:0007165=PMID:9210375, GO:0005737=PMID:9210375, GO:0007154=PMID:9210375, GO:0005856=GO_REF:0000039, GO:0005938=GO_REF:0000039} Q15642 Cdc42-interacting protein 4 protein 20130415 {GO:0051056=TAS, GO:0048471=IEA, GO:0005794=IEA, GO:0030036=NAS, GO:0007264=TAS, GO:0001891=IEA, GO:0042995=IEA, GO:0005764=IEA, GO:0042802=IPI, GO:0005829=TAS, GO:0006897=IEA, GO:0008289=IEA, GO:0007165=TAS, GO:0005737=NAS, GO:0007154=NAS, GO:0005856=IEA, GO:0005938=IEA} actin cytoskeleton organization, cell communication, endocytosis, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction Golgi apparatus, cell cortex, cell projection, cytoplasm, cytoskeleton, cytosol, lysosome, perinuclear region of cytoplasm, phagocytic cup identical protein binding, lipid binding Human UniProtKB:Q15642 TRIP11 HPA UniProtKB {GO:0005515=PMID:17438371, GO:0005794=GO_REF:0000052, GO:0006366=PMID:9256431, GO:0016020=GO_REF:0000037, GO:0003713=PMID:9256431, GO:0005634=GO_REF:0000052, GO:0005856=GO_REF:0000039, GO:0043231=GO_REF:0000052, GO:0000042=GO_REF:0000002} Q15643 Thyroid receptor-interacting protein 11 protein 20101115 {GO:0005515=IPI, GO:0005794=IDA, GO:0006366=TAS, GO:0016020=IEA, GO:0003713=TAS, GO:0005634=IDA, GO:0005856=IEA, GO:0043231=IDA, GO:0000042=IEA} protein targeting to Golgi, transcription from RNA polymerase II promoter Golgi apparatus, cytoskeleton, intracellular membrane-bounded organelle, membrane, nucleus protein binding, transcription coactivator activity Human TRIP12 UniProtKB UniProtKB {GO:0005515=PMID:18627766, GO:2000780=PMID:22884692, GO:0004842=PMID:18627766, GO:0016567=GO_REF:0000029, GO:0005634=GO_REF:0000033, GO:0009790=GO_REF:0000024, GO:0005575=GO_REF:0000015, GO:0006974=PMID:22884692, GO:0005622=GO_REF:0000002, GO:0046966=PMID:7776974, GO:0005737=GO_REF:0000033, GO:0006281=GO_REF:0000037, GO:1901315=PMID:22884692, GO:0042787=PMID:18627766, GO:0005654=PMID:20208519} Q14669 E3 ubiquitin-protein ligase TRIP12 protein 20120824 {GO:0005515=IPI, GO:2000780=IMP, GO:0004842=IDA, GO:0016567=NAS, GO:0005634=IBA, GO:0009790=ISS, GO:0005575=ND, GO:0006974=IMP, GO:0005622=IEA, GO:0046966=IDA, GO:0005737=IBA, GO:0006281=IEA, GO:1901315=IMP, GO:0042787=IDA, GO:0005654=IDA} DNA repair, embryo development, negative regulation of double-strand break repair, negative regulation of histone H2A K63-linked ubiquitination, protein ubiquitination, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, response to DNA damage stimulus cellular_component, cytoplasm, intracellular, nucleoplasm, nucleus protein binding, thyroid hormone receptor binding, ubiquitin-protein ligase activity Human UniProtKB:Q13564 TRIP13 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0003712=PMID:7776974, GO:0017111=GO_REF:0000002, GO:0006366=PMID:7776974, GO:0000239=GO_REF:0000019, GO:0048477=GO_REF:0000024, GO:0007286=GO_REF:0000019, GO:0005634=PMID:7776974, GO:0001556=GO_REF:0000019, GO:0007283=GO_REF:0000024, GO:0005524=PMID:9223484, GO:0042802=GO_REF:0000019, GO:0006302=GO_REF:0000024, GO:0007144=GO_REF:0000019, GO:0007130=GO_REF:0000024, GO:0001673=GO_REF:0000019, GO:0007141=GO_REF:0000019, GO:0007131=GO_REF:0000024} Q15645 Pachytene checkpoint protein 2 homolog protein 20130415 {GO:0005515=IPI, GO:0003712=TAS, GO:0017111=IEA, GO:0006366=TAS, GO:0000239=IEA, GO:0048477=ISS, GO:0007286=IEA, GO:0005634=TAS, GO:0001556=IEA, GO:0007283=ISS, GO:0005524=NAS, GO:0042802=IEA, GO:0006302=ISS, GO:0007144=IEA, GO:0007130=ISS, GO:0001673=IEA, GO:0007141=IEA, GO:0007131=ISS} double-strand break repair, female meiosis I, male meiosis I, oocyte maturation, oogenesis, pachytene, reciprocal meiotic recombination, spermatid development, spermatogenesis, synaptonemal complex assembly, transcription from RNA polymerase II promoter male germ cell nucleus, nucleus ATP binding, identical protein binding, nucleoside-triphosphatase activity, protein binding, transcription cofactor activity Human UniProtKB:Q9H0W9 TRIP4 HPA UniProtKB {GO:0016922=PMID:10454579, GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000002, GO:0006366=PMID:7776974, GO:0005815=GO_REF:0000039, GO:0003713=PMID:7776974, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0045893=PMID:10454579} Q15650 Activating signal cointegrator 1 protein 20090616 {GO:0016922=IDA, GO:0005737=IDA, GO:0006355=IEA, GO:0006366=TAS, GO:0005815=IEA, GO:0003713=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0045893=NAS} positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter cytoplasm, microtubule organizing center, nucleolus, nucleus ligand-dependent nuclear receptor binding, transcription coactivator activity, zinc ion binding Human TRIP6 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0006355=GO_REF:0000037, GO:0005149=PMID:15657077, GO:0030335=PMID:14688263, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037, GO:0046966=PMID:9598321, GO:0045323=PMID:15657077, GO:0005737=GO_REF:0000039, GO:0008588=PMID:15657077, GO:0048041=PMID:14688263, GO:0008270=GO_REF:0000002, GO:0005856=GO_REF:0000039, GO:0019900=PMID:15657077, GO:0005925=PMID:14688263} Q15654 Thyroid receptor-interacting protein 6 protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0005149=IDA, GO:0030335=IMP, GO:0005634=IEA, GO:0006351=IEA, GO:0046966=NAS, GO:0045323=IDA, GO:0005737=IEA, GO:0008588=IDA, GO:0048041=NAS, GO:0008270=IEA, GO:0005856=IEA, GO:0019900=IPI, GO:0005925=IDA} focal adhesion assembly, positive regulation of cell migration, regulation of transcription, DNA-dependent, release of cytoplasmic sequestered NF-kappaB, transcription, DNA-dependent cytoplasm, cytoskeleton, focal adhesion, interleukin-1 receptor complex, nucleus interleukin-1 receptor binding, kinase binding, protein binding, thyroid hormone receptor binding, zinc ion binding Human UniProtKB:Q96I34 TRIT1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0052381=PMID:11111046, GO:0005575=GO_REF:0000015, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0016740=GO_REF:0000038, GO:0008033=GO_REF:0000029} Q9H3H1 tRNA dimethylallyltransferase, mitochondrial protein 20021106 {GO:0005739=IEA, GO:0052381=TAS, GO:0005575=ND, GO:0005524=IEA, GO:0046872=IEA, GO:0016740=IEA, GO:0008033=NAS} tRNA processing cellular_component, mitochondrion ATP binding, metal ion binding, tRNA dimethylallyltransferase activity, transferase activity Human TRMT1 InterPro UniProtKB {GO:0004809=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q9NXH9 tRNA (guanine(26)-N(2))-dimethyltransferase protein 20130413 {GO:0004809=IEA, GO:0003723=IEA, GO:0008270=IEA} RNA binding, tRNA (guanine-N2-)-methyltransferase activity, zinc ion binding Human InterPro:IPR000571 TRMT11 UniProtKB UniProtKB {GO:0008168=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0008033=GO_REF:0000037} Q7Z4G4 tRNA (guanine(10)-N2)-methyltransferase homolog protein 20130413 {GO:0008168=IEA, GO:0003676=IEA, GO:0008033=IEA} tRNA processing methyltransferase activity, nucleic acid binding Human UniProtKB-KW:KW-0489 TRMT112 MGI UniProtKB {GO:0005515=PMID:18539146, GO:0043234=PMID:18539146, GO:0018364=PMID:18539146, GO:0008276=PMID:18539146} Q9UI30 tRNA methyltransferase 112 homolog protein 20090609 {GO:0005515=IPI, GO:0043234=IDA, GO:0018364=IDA, GO:0008276=IDA} peptidyl-glutamine methylation protein complex protein binding, protein methyltransferase activity Human TRMT1L ENSEMBL UniProtKB {GO:0004809=GO_REF:0000002, GO:0008344=GO_REF:0000019, GO:0003723=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q7Z2T5 TRMT1-like protein protein 20130413 {GO:0004809=IEA, GO:0008344=IEA, GO:0003723=IEA, GO:0008270=IEA} adult locomotory behavior RNA binding, tRNA (guanine-N2-)-methyltransferase activity, zinc ion binding Human Ensembl:ENSMUSP00000068309 TRMT2A UniProtKB UniProtKB {GO:0006396=GO_REF:0000002, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0008173=GO_REF:0000002} Q8IZ69 tRNA (uracil-5-)-methyltransferase homolog A protein 20130413 {GO:0006396=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0003676=IEA, GO:0008173=IEA} RNA processing RNA binding, RNA methyltransferase activity, nucleic acid binding, nucleotide binding Human UniProtKB-KW:KW-0694 TRMT2B ENSEMBL UniProtKB {GO:0005739=GO_REF:0000019, GO:0030697=GO_REF:0000003} Q96GJ1 tRNA (uracil(54)-C(5))-methyltransferase homolog protein 20130413 {GO:0005739=IEA, GO:0030697=IEA} mitochondrion S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity Human Ensembl:ENSMUSP00000108878 TRMT5 UniProtKB UniProtKB {GO:0005759=GO_REF:0000039, GO:0052906=GO_REF:0000003, GO:0005634=GO_REF:0000039} Q32P41 tRNA (guanine(37)-N1)-methyltransferase protein 20130413 {GO:0005759=IEA, GO:0052906=IEA, GO:0005634=IEA} mitochondrial matrix, nucleus tRNA (guanine(37)-N(1))-methyltransferase activity Human UniProtKB-SubCell:SL-0170 TRMT6 UniProtKB UniProtKB {GO:0006446=GO_REF:0000002, GO:0008168=GO_REF:0000038, GO:0003743=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0008033=GO_REF:0000037} Q9UJA5 tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 protein 20130413 {GO:0006446=IEA, GO:0008168=IEA, GO:0003743=IEA, GO:0005634=IEA, GO:0008033=IEA} regulation of translational initiation, tRNA processing nucleus methyltransferase activity, translation initiation factor activity Human UniProtKB-SubCell:SL-0191 TRMT61A UniProtKB UniProtKB {GO:0031515=GO_REF:0000002, GO:0016429=GO_REF:0000002, GO:0005634=GO_REF:0000039} Q96FX7 tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A protein 20130413 {GO:0031515=IEA, GO:0016429=IEA, GO:0005634=IEA} nucleus, tRNA (m1A) methyltransferase complex tRNA (adenine-N1-)-methyltransferase activity Human UniProtKB-SubCell:SL-0191 TRMT61B IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0005739=PMID:23097428, GO:0070901=PMID:23097428, GO:0031515=GO_REF:0000002, GO:0016429=PMID:23097428, GO:0051260=PMID:23097428} Q9BVS5 tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial protein 20130415 {GO:0005515=IPI, GO:0005739=IDA, GO:0070901=IDA, GO:0031515=IEA, GO:0016429=IDA, GO:0051260=IDA} mitochondrial tRNA methylation, protein homooligomerization mitochondrion, tRNA (m1A) methyltransferase complex protein binding, tRNA (adenine-N1-)-methyltransferase activity Human UniProtKB:Q92985 TRMU UniProtKB UniProtKB {GO:0005739=GO_REF:0000024, GO:0016783=GO_REF:0000002, GO:0004808=GO_REF:0000029, GO:0006399=GO_REF:0000029, GO:0005737=GO_REF:0000002, GO:0000049=GO_REF:0000037, GO:0008168=GO_REF:0000038, GO:0005524=GO_REF:0000037, GO:0008033=GO_REF:0000002} Q2PPL5 Mitochondrial tRNA-specific 2-thiouridylase 1 protein 20130413 {GO:0005739=ISS, GO:0016783=IEA, GO:0004808=NAS, GO:0006399=NAS, GO:0005737=IEA, GO:0000049=IEA, GO:0008168=IEA, GO:0005524=IEA, GO:0008033=IEA} tRNA metabolic process, tRNA processing cytoplasm, mitochondrion ATP binding, methyltransferase activity, sulfurtransferase activity, tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity, tRNA binding Human UniProtKB-KW:KW-0489 TRNAU1AP HGNC UniProtKB {GO:0005737=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0001514=GO_REF:0000024, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000024} Q9NX07 tRNA selenocysteine 1-associated protein 1 protein 20051212 {GO:0005737=IEA, GO:0000166=IEA, GO:0001514=ISS, GO:0003723=IEA, GO:0005634=ISS} selenocysteine incorporation cytoplasm, nucleus RNA binding, nucleotide binding Human UniProtKB:Q80VC6 TRNT1 HPA UniProtKB {GO:0009022=GO_REF:0000002, GO:0005813=GO_REF:0000052, GO:0052927=GO_REF:0000003, GO:0000049=PMID:11504732, GO:0006626=PMID:11504732, GO:0004810=PMID:11504732, GO:0005524=PMID:11504732, GO:0042780=PMID:11504732, GO:0005739=GO_REF:0000052, GO:0005622=GO_REF:0000054, GO:0001680=GO_REF:0000003, GO:0052929=GO_REF:0000003, GO:0052928=GO_REF:0000003} Q96Q11 CCA tRNA nucleotidyltransferase 1, mitochondrial protein 20110516 {GO:0009022=IEA, GO:0005813=IDA, GO:0052927=IEA, GO:0000049=IDA, GO:0006626=TAS, GO:0004810=IDA, GO:0005524=TAS, GO:0042780=IDA, GO:0005739=IDA, GO:0005622=IDA, GO:0001680=IEA, GO:0052929=IEA, GO:0052928=IEA} protein targeting to mitochondrion, tRNA 3'-end processing, tRNA 3'-terminal CCA addition centrosome, intracellular, mitochondrion ATP binding, ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity, CTP:3'-cytidine-tRNA cytidylyltransferase activity, CTP:tRNA cytidylyltransferase activity, tRNA adenylyltransferase activity, tRNA binding, tRNA nucleotidyltransferase activity Human TRO IntAct UniProtKB {GO:0005515=PMID:9560222, GO:0030308=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0005886=PMID:7758945, GO:0007566=PMID:7758945, GO:0005887=PMID:7758945, GO:0005634=GO_REF:0000019, GO:0007156=PMID:7758945} Q12816 Trophinin protein 20130415 {GO:0005515=IPI, GO:0030308=IEA, GO:0005737=IEA, GO:0005886=TAS, GO:0007566=TAS, GO:0005887=TAS, GO:0005634=IEA, GO:0007156=TAS} embryo implantation, homophilic cell adhesion, negative regulation of cell growth cytoplasm, integral to plasma membrane, nucleus, plasma membrane protein binding Human UniProtKB:Q13895 TROAP IntAct UniProtKB {GO:0005515=PMID:9560222, GO:0005737=GO_REF:0000039, GO:0007155=GO_REF:0000037} Q12815 Tastin protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0007155=IEA} cell adhesion cytoplasm protein binding Human UniProtKB:Q13895 TROVE2 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0030529=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0060271=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006383=PMID:3200833, GO:0046872=GO_REF:0000037} Q5LJA0 TROVE domain family, member 2, isoform CRA_e protein 20101115 {GO:0005737=IDA, GO:0030529=IEA, GO:0003723=IEA, GO:0060271=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006383=TAS, GO:0046872=IEA} cilium morphogenesis, transcription from RNA polymerase III promoter cytoplasm, nucleolus, nucleus, ribonucleoprotein complex RNA binding, metal ion binding Human TRPA1 PINC UniProtKB {GO:0042542=GO_REF:0000019, GO:0005262=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0009409=GO_REF:0000019, GO:0032421=GO_REF:0000019, GO:0005887=PMID:10066796, GO:0050955=GO_REF:0000019, GO:0050968=GO_REF:0000019, GO:0048265=GO_REF:0000019, GO:0050966=GO_REF:0000019, GO:0016021=GO_REF:0000038, GO:0005216=GO_REF:0000002, GO:0015267=PMID:10066796, GO:0006811=PMID:10066796} O75762 Transient receptor potential cation channel subfamily A member 1 protein 20030904 {GO:0042542=IEA, GO:0005262=IEA, GO:0042493=IEA, GO:0009409=IEA, GO:0032421=IEA, GO:0005887=TAS, GO:0050955=IEA, GO:0050968=IEA, GO:0048265=IEA, GO:0050966=IEA, GO:0016021=IEA, GO:0005216=IEA, GO:0015267=TAS, GO:0006811=TAS} detection of chemical stimulus involved in sensory perception of pain, detection of mechanical stimulus involved in sensory perception of pain, ion transport, response to cold, response to drug, response to hydrogen peroxide, response to pain, thermoception integral to membrane, integral to plasma membrane, stereocilium bundle calcium channel activity, channel activity, ion channel activity Human TRPC1 BHF-UCL UniProtKB {GO:0005515=PMID:14505576, GO:0005262=PMID:8646775, GO:0005261=Reactome:REACT_118688, GO:0005886=PMID:14505576, GO:0051480=PMID:19052258, GO:0030017=GO_REF:0000019, GO:0070679=PMID:14505576, GO:0051592=PMID:14505576, GO:0016323=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0005887=PMID:7568191, GO:0043034=GO_REF:0000019, GO:0015279=GO_REF:0000019, GO:0045121=GO_REF:0000019, GO:0006816=PMID:8646775, GO:0016021=GO_REF:0000002, GO:0051281=PMID:19052258, GO:0046541=GO_REF:0000019} P48995 Short transient receptor potential channel 1 protein 20111207 {GO:0005515=IPI, GO:0005262=TAS, GO:0005261=EXP, GO:0005886=IDA, GO:0051480=IDA, GO:0030017=IEA, GO:0070679=IDA, GO:0051592=IDA, GO:0016323=IEA, GO:0043234=IEA, GO:0007411=TAS, GO:0005887=TAS, GO:0043034=IEA, GO:0015279=IEA, GO:0045121=IEA, GO:0006816=TAS, GO:0016021=IEA, GO:0051281=IDA, GO:0046541=IEA} axon guidance, calcium ion transport, cytosolic calcium ion homeostasis, positive regulation of release of sequestered calcium ion into cytosol, response to calcium ion, saliva secretion basolateral plasma membrane, costamere, integral to membrane, integral to plasma membrane, membrane raft, plasma membrane, protein complex, sarcomere calcium channel activity, cation channel activity, inositol 1,4,5 trisphosphate binding, protein binding, store-operated calcium channel activity Human TRPC3 BHF-UCL UniProtKB {GO:0005515=PMID:15757897, GO:0005262=PMID:9930701, GO:0005886=Reactome:REACT_24007, GO:0010524=PMID:21062895, GO:0030168=Reactome:REACT_798, GO:0070679=PMID:14505576, GO:0051592=PMID:21062895, GO:0007596=Reactome:REACT_604, GO:0005887=PMID:9368034, GO:0007411=Reactome:REACT_18266, GO:0070588=PMID:21062895, GO:0033198=PMID:21062895, GO:0006816=PMID:9215637, GO:0015279=PMID:9215637, GO:0016021=GO_REF:0000038, GO:0007602=PMID:9215637} Q13507 Short transient receptor potential channel 3 protein 20111207 {GO:0005515=IPI, GO:0005262=TAS, GO:0005886=TAS, GO:0010524=IDA, GO:0030168=TAS, GO:0070679=IDA, GO:0051592=IDA, GO:0007596=TAS, GO:0005887=IDA, GO:0007411=TAS, GO:0070588=IDA, GO:0033198=IDA, GO:0006816=TAS, GO:0015279=TAS, GO:0016021=IEA, GO:0007602=TAS} axon guidance, blood coagulation, calcium ion transmembrane transport, calcium ion transport, phototransduction, platelet activation, positive regulation of calcium ion transport into cytosol, response to ATP, response to calcium ion integral to membrane, integral to plasma membrane, plasma membrane calcium channel activity, inositol 1,4,5 trisphosphate binding, protein binding, store-operated calcium channel activity Human TRPC4 BHF-UCL UniProtKB {GO:0005515=PMID:15757897, GO:0005262=GO_REF:0000002, GO:0045296=PMID:19996314, GO:0008013=PMID:19996314, GO:0005886=PMID:16254212, GO:0009986=PMID:19996314, GO:0014051=GO_REF:0000019, GO:0034704=PMID:20164195, GO:0016323=PMID:19996314, GO:0070679=GO_REF:0000019, GO:0070509=PMID:19996314, GO:0005911=PMID:19996314, GO:0007411=Reactome:REACT_18266, GO:0005901=GO_REF:0000019, GO:0015279=PMID:16254212, GO:0006816=PMID:8646775, GO:0030863=PMID:16254212, GO:0016021=GO_REF:0000002} Q9UBN4 Short transient receptor potential channel 4 protein 20100722 {GO:0005515=IPI, GO:0005262=IEA, GO:0045296=IPI, GO:0008013=IPI, GO:0005886=IDA, GO:0009986=IDA, GO:0014051=IEA, GO:0034704=IDA, GO:0016323=IDA, GO:0070679=IEA, GO:0070509=IDA, GO:0005911=IDA, GO:0007411=TAS, GO:0005901=IEA, GO:0015279=IMP, GO:0006816=TAS, GO:0030863=IDA, GO:0016021=IEA} axon guidance, calcium ion import, calcium ion transport, gamma-aminobutyric acid secretion basolateral plasma membrane, calcium channel complex, caveola, cell surface, cell-cell junction, cortical cytoskeleton, integral to membrane, plasma membrane beta-catenin binding, cadherin binding, calcium channel activity, inositol 1,4,5 trisphosphate binding, protein binding, store-operated calcium channel activity colocalizes_with Human TRPC4AP IntAct UniProtKB {GO:0005515=PMID:19389623, GO:0006511=PMID:20551172, GO:0016567=PMID:20551172, GO:0019902=PMID:19389623, GO:0031464=PMID:20551172} Q8TEL6 Short transient receptor potential channel 4-associated protein protein 20130415 {GO:0005515=IPI, GO:0006511=IDA, GO:0016567=IDA, GO:0019902=IDA, GO:0031464=IDA} protein ubiquitination, ubiquitin-dependent protein catabolic process Cul4A-RING ubiquitin ligase complex phosphatase binding, protein binding Human UniProtKB:P62136 TRPC5 Reactome UniProtKB {GO:0005515=PMID:20164195, GO:0070679=GO_REF:0000019, GO:0005262=PMID:20164195, GO:0007411=Reactome:REACT_18266, GO:0005887=PMID:10493832, GO:0015279=PMID:10493832, GO:0006816=PMID:10493832, GO:0034704=PMID:20164195, GO:0007399=PMID:10493832} Q9UL62 Short transient receptor potential channel 5 protein 20130301 {GO:0005515=IPI, GO:0070679=IEA, GO:0005262=IDA, GO:0007411=TAS, GO:0005887=TAS, GO:0015279=TAS, GO:0006816=TAS, GO:0034704=IDA, GO:0007399=TAS} axon guidance, calcium ion transport, nervous system development calcium channel complex, integral to plasma membrane calcium channel activity, inositol 1,4,5 trisphosphate binding, protein binding, store-operated calcium channel activity Human TRPC6 BHF-UCL UniProtKB {GO:0005515=PMID:15757897, GO:0005262=GO_REF:0000002, GO:0005886=Reactome:REACT_24007, GO:0051928=PMID:10998353, GO:0030168=Reactome:REACT_798, GO:0032414=PMID:10998353, GO:0007204=GO_REF:0000019, GO:0070679=PMID:14505576, GO:0007411=Reactome:REACT_18266, GO:0007596=Reactome:REACT_604, GO:0036057=GO_REF:0000019, GO:0015279=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0006812=PMID:9930701} Q9Y210 Short transient receptor potential channel 6 protein 20111207 {GO:0005515=IPI, GO:0005262=IEA, GO:0005886=TAS, GO:0051928=IDA, GO:0030168=TAS, GO:0032414=IDA, GO:0007204=IEA, GO:0070679=IDA, GO:0007411=TAS, GO:0007596=TAS, GO:0036057=IEA, GO:0015279=IEA, GO:0016021=IEA, GO:0006812=TAS} axon guidance, blood coagulation, cation transport, elevation of cytosolic calcium ion concentration, platelet activation, positive regulation of calcium ion transport, positive regulation of ion transmembrane transporter activity integral to membrane, plasma membrane, slit diaphragm calcium channel activity, inositol 1,4,5 trisphosphate binding, protein binding, store-operated calcium channel activity Human TRPC7 Reactome UniProtKB {GO:0005515=PMID:21402151, GO:0005262=GO_REF:0000019, GO:0005886=Reactome:REACT_24007, GO:0007596=Reactome:REACT_604, GO:0007411=Reactome:REACT_18266, GO:0030168=Reactome:REACT_798, GO:0005635=GO_REF:0000039, GO:0006828=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q9HCX4 Short transient receptor potential channel 7 protein 20130301 {GO:0005515=IPI, GO:0005262=IEA, GO:0005886=TAS, GO:0007596=TAS, GO:0007411=TAS, GO:0030168=TAS, GO:0005635=IEA, GO:0006828=IEA, GO:0016021=IEA} axon guidance, blood coagulation, manganese ion transport, platelet activation integral to membrane, nuclear envelope, plasma membrane calcium channel activity, protein binding Human TRPM1 GOC UniProtKB {GO:0007165=GO_REF:0000019, GO:0005262=PMID:9806836, GO:0005261=GO_REF:0000019, GO:0005887=PMID:9806836, GO:0035841=GO_REF:0000019, GO:0046548=GO_REF:0000019, GO:0070588=PMID:9806836, GO:0006810=PMID:9806836, GO:0071482=PMID:19896109, GO:0016021=GO_REF:0000038, GO:0007601=PMID:19878917, GO:0005216=GO_REF:0000002} Q7Z4N2 Transient receptor potential cation channel subfamily M member 1 protein 20130413 {GO:0007165=IEA, GO:0005262=TAS, GO:0005261=IEA, GO:0005887=TAS, GO:0035841=IEA, GO:0046548=IEA, GO:0070588=TAS, GO:0006810=TAS, GO:0071482=IMP, GO:0016021=IEA, GO:0007601=IMP, GO:0005216=IEA} calcium ion transmembrane transport, cellular response to light stimulus, retinal rod cell development, signal transduction, transport, visual perception integral to membrane, integral to plasma membrane, new growing cell tip calcium channel activity, cation channel activity, ion channel activity Human TRPM2 PINC UniProtKB {GO:0005262=GO_REF:0000037, GO:0047631=GO_REF:0000003, GO:0016787=GO_REF:0000002, GO:0005886=GO_REF:0000019, GO:0005887=PMID:9806837, GO:0005272=GO_REF:0000037, GO:0005384=GO_REF:0000019, GO:0006816=PMID:9806837, GO:0016021=GO_REF:0000038, GO:0005216=GO_REF:0000002, GO:0033194=GO_REF:0000019} O94759 Transient receptor potential cation channel subfamily M member 2 protein 20030904 {GO:0005262=IEA, GO:0047631=IEA, GO:0016787=IEA, GO:0005886=IEA, GO:0005887=TAS, GO:0005272=IEA, GO:0005384=IEA, GO:0006816=TAS, GO:0016021=IEA, GO:0005216=IEA, GO:0033194=IEA} calcium ion transport, response to hydroperoxide integral to membrane, integral to plasma membrane, plasma membrane ADP-ribose diphosphatase activity, calcium channel activity, hydrolase activity, ion channel activity, manganese ion transmembrane transporter activity, sodium channel activity Human TRPM4 UniProtKB UniProtKB {GO:0005516=GO_REF:0000037, GO:0005262=GO_REF:0000019, GO:0008284=PMID:20625999, GO:0005794=PMID:19945433, GO:0005886=PMID:19945433, GO:0005783=PMID:19945433, GO:0016925=PMID:19726882, GO:0090263=PMID:20625999, GO:0002407=GO_REF:0000024, GO:0002724=PMID:20656926, GO:0005524=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0005227=GO_REF:0000024, GO:0005216=GO_REF:0000002} Q8TD43 Transient receptor potential cation channel subfamily M member 4 protein 20100929 {GO:0005516=IEA, GO:0005262=IEA, GO:0008284=IDA, GO:0005794=IDA, GO:0005886=IDA, GO:0005783=IDA, GO:0016925=IDA, GO:0090263=IDA, GO:0002407=ISS, GO:0002724=IDA, GO:0005524=IEA, GO:0016021=IEA, GO:0005227=ISS, GO:0005216=IEA} dendritic cell chemotaxis, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of cell proliferation, protein sumoylation, regulation of T cell cytokine production Golgi apparatus, endoplasmic reticulum, integral to membrane, plasma membrane ATP binding, calcium activated cation channel activity, calcium channel activity, calmodulin binding, ion channel activity Human TRPM6 UniProtKB UniProtKB {GO:0005515=PMID:18258429, GO:0016324=GO_REF:0000019, GO:0005262=GO_REF:0000037, GO:0004674=GO_REF:0000037, GO:0009636=PMID:17575980, GO:0031526=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0005216=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q9BX84 Transient receptor potential cation channel subfamily M member 6 protein 20110414 {GO:0005515=IPI, GO:0016324=IEA, GO:0005262=IEA, GO:0004674=IEA, GO:0009636=IDA, GO:0031526=IEA, GO:0016021=IEA, GO:0005524=IEA, GO:0005216=IEA, GO:0046872=IEA} response to toxic substance apical plasma membrane, brush border membrane, integral to membrane ATP binding, calcium channel activity, ion channel activity, metal ion binding, protein binding, protein serine/threonine kinase activity Human UniProtKB:P68040 TRPM7 ENSEMBL UniProtKB {GO:0008219=GO_REF:0000037, GO:0005262=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0031032=GO_REF:0000019, GO:0003779=GO_REF:0000019, GO:0016340=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0001726=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0046777=GO_REF:0000019, GO:0004674=GO_REF:0000037, GO:0017022=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0005216=GO_REF:0000002} Q96QT4 Transient receptor potential cation channel subfamily M member 7 protein 20130413 {GO:0008219=IEA, GO:0005262=IEA, GO:0005886=IEA, GO:0031032=IEA, GO:0003779=IEA, GO:0016340=IEA, GO:0005524=IEA, GO:0001726=IEA, GO:0046872=IEA, GO:0046777=IEA, GO:0004674=IEA, GO:0017022=IEA, GO:0016021=IEA, GO:0005216=IEA} actomyosin structure organization, calcium-dependent cell-matrix adhesion, cell death, protein autophosphorylation integral to membrane, plasma membrane, ruffle ATP binding, actin binding, calcium channel activity, ion channel activity, metal ion binding, myosin binding, protein serine/threonine kinase activity Human Ensembl:ENSMUSP00000099513 TRPM8 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0009409=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0045121=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0005216=GO_REF:0000019} Q7Z2W7 Transient receptor potential cation channel subfamily M member 8 protein 20130413 {GO:0005886=IEA, GO:0009409=IEA, GO:0005789=IEA, GO:0045121=IEA, GO:0016021=IEA, GO:0005216=IEA} response to cold endoplasmic reticulum membrane, integral to membrane, membrane raft, plasma membrane ion channel activity Human UniProtKB-SubCell:SL-0370 TRPS1 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0043565=GO_REF:0000002, GO:0001501=PMID:10615131, GO:0003700=GO_REF:0000002, GO:0006366=PMID:10615131, GO:0032330=GO_REF:0000024, GO:0005634=PMID:12885770, GO:0008270=GO_REF:0000002, GO:0000122=PMID:12885770, GO:0006607=PMID:10615131, GO:0045892=GO_REF:0000019} Q9UHF7 Zinc finger transcription factor Trps1 protein 20130415 {GO:0005515=IPI, GO:0043565=IEA, GO:0001501=TAS, GO:0003700=IEA, GO:0006366=TAS, GO:0032330=ISS, GO:0005634=IDA, GO:0008270=IEA, GO:0000122=IDA, GO:0006607=TAS, GO:0045892=IEA} NLS-bearing substrate import into nucleus, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, regulation of chondrocyte differentiation, skeletal system development, transcription from RNA polymerase II promoter nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB:Q9Q2G4 TRPT1 UniProtKB UniProtKB {GO:0006388=GO_REF:0000002, GO:0000215=GO_REF:0000003, GO:0008665=GO_REF:0000019, GO:0016772=GO_REF:0000002} Q86TN4 tRNA 2'-phosphotransferase 1 protein 20130413 {GO:0006388=IEA, GO:0000215=IEA, GO:0008665=IEA, GO:0016772=IEA} tRNA splicing, via endonucleolytic cleavage and ligation 2'-phosphotransferase activity, tRNA 2'-phosphotransferase activity, transferase activity, transferring phosphorus-containing groups Human EC:2.7.1.160 TRPV1 PINC UniProtKB {GO:0005516=GO_REF:0000037, GO:0005262=GO_REF:0000037, GO:0030054=GO_REF:0000037, GO:0007635=PMID:9349813, GO:0005524=GO_REF:0000037, GO:0032591=GO_REF:0000039, GO:0005887=PMID:9349813, GO:0045211=GO_REF:0000024, GO:0006810=PMID:9349813, GO:0050955=PMID:123456, GO:0016021=PMID:123456, GO:0005216=GO_REF:0000002, GO:0007166=PMID:9349813} Q8NER1 Transient receptor potential cation channel subfamily V member 1 protein 20061106 {GO:0005516=IEA, GO:0005262=IEA, GO:0030054=IEA, GO:0007635=TAS, GO:0005524=IEA, GO:0032591=IEA, GO:0005887=TAS, GO:0045211=ISS, GO:0006810=TAS, GO:0050955=IDA, GO:0016021=IDA, GO:0005216=IEA, GO:0007166=TAS} cell surface receptor signaling pathway, chemosensory behavior, thermoception, transport cell junction, dendritic spine membrane, integral to membrane, integral to plasma membrane, postsynaptic membrane ATP binding, calcium channel activity, calmodulin binding, ion channel activity Human TRPV2 MGI UniProtKB {GO:0042470=GO_REF:0000039, GO:0005262=GO_REF:0000019, GO:0005261=PMID:10201375, GO:0005886=PMID:10201375, GO:0009408=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0015075=PMID:10201375, GO:0045773=GO_REF:0000019, GO:0032584=GO_REF:0000019, GO:0044295=GO_REF:0000019, GO:0090280=GO_REF:0000019, GO:0044297=GO_REF:0000019, GO:0012505=GO_REF:0000019, GO:0009266=PMID:10201375, GO:0005622=GO_REF:0000002, GO:0005887=PMID:10201375, GO:0006810=PMID:10201375, GO:0070588=GO_REF:0000002, GO:0016021=GO_REF:0000002, GO:0005216=PMID:10201375, GO:0007600=PMID:10201375} Q9Y5S1 Transient receptor potential cation channel subfamily V member 2 protein 20081007 {GO:0042470=IEA, GO:0005262=IEA, GO:0005261=IDA, GO:0005886=IDA, GO:0009408=IEA, GO:0009986=IEA, GO:0015075=TAS, GO:0045773=IEA, GO:0032584=IEA, GO:0044295=IEA, GO:0090280=IEA, GO:0044297=IEA, GO:0012505=IEA, GO:0009266=IDA, GO:0005622=IEA, GO:0005887=TAS, GO:0006810=TAS, GO:0070588=IEA, GO:0016021=IEA, GO:0005216=TAS, GO:0007600=TAS} calcium ion transmembrane transport, positive regulation of axon extension, positive regulation of calcium ion import, response to heat, response to temperature stimulus, sensory perception, transport axonal growth cone, cell body, cell surface, endomembrane system, growth cone membrane, integral to membrane, integral to plasma membrane, intracellular, melanosome, plasma membrane calcium channel activity, cation channel activity, ion channel activity, ion transmembrane transporter activity Human TRPV3 UniProtKB UniProtKB {GO:0009266=GO_REF:0000019, GO:0005262=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0042636=PMID:21593771, GO:0005216=GO_REF:0000002} Q8NET8 Transient receptor potential cation channel subfamily V member 3 protein 20120511 {GO:0009266=IEA, GO:0005262=IEA, GO:0016021=IEA, GO:0042636=IMP, GO:0005216=IEA} negative regulation of hair cycle, response to temperature stimulus integral to membrane calcium channel activity, ion channel activity Human TRPV4 BHF-UCL UniProtKB {GO:0008017=GO_REF:0000024, GO:0005516=PMID:12724311, GO:0008219=GO_REF:0000037, GO:0005881=GO_REF:0000024, GO:0005886=GO_REF:0000024, GO:0030175=GO_REF:0000024, GO:0007204=PMID:18458941, GO:0043622=GO_REF:0000024, GO:0006884=PMID:12724311, GO:0030426=GO_REF:0000024, GO:0030103=GO_REF:0000019, GO:0051015=GO_REF:0000024, GO:0005912=GO_REF:0000024, GO:0005080=GO_REF:0000024, GO:0006816=PMID:18458941, GO:0007015=GO_REF:0000024, GO:0042169=GO_REF:0000024, GO:0005262=PMID:18458941, GO:0005261=PMID:12724311, GO:0071476=GO_REF:0000024, GO:0007231=GO_REF:0000024, GO:0031117=GO_REF:0000024, GO:0019901=PMID:12538589, GO:0031532=GO_REF:0000024, GO:0043014=GO_REF:0000024, GO:0006874=PMID:12724311, GO:0048487=GO_REF:0000024, GO:0003779=GO_REF:0000024, GO:0032587=GO_REF:0000024, GO:0042538=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0030027=GO_REF:0000024, GO:0009612=PMID:15753126, GO:0005929=GO_REF:0000019, GO:0070509=GO_REF:0000024, GO:0046785=GO_REF:0000024, GO:0047484=GO_REF:0000019, GO:0010977=GO_REF:0000024, GO:0007043=GO_REF:0000024, GO:0016021=PMID:11025659, GO:0030864=GO_REF:0000024, GO:0005925=GO_REF:0000024, GO:0005034=GO_REF:0000019} Q9HBA0 Transient receptor potential cation channel subfamily V member 4 protein 20110214 {GO:0008017=ISS, GO:0005516=IMP, GO:0008219=IEA, GO:0005881=ISS, GO:0005886=ISS, GO:0030175=ISS, GO:0007204=IDA, GO:0043622=ISS, GO:0006884=TAS, GO:0030426=ISS, GO:0030103=IEA, GO:0051015=ISS, GO:0005912=ISS, GO:0005080=ISS, GO:0006816=IDA, GO:0007015=ISS, GO:0042169=ISS, GO:0005262=IDA, GO:0005261=IDA, GO:0071476=ISS, GO:0007231=ISS, GO:0031117=ISS, GO:0019901=IPI, GO:0031532=ISS, GO:0043014=ISS, GO:0006874=IDA, GO:0048487=ISS, GO:0003779=ISS, GO:0032587=ISS, GO:0042538=IEA, GO:0005524=IEA, GO:0030027=ISS, GO:0009612=TAS, GO:0005929=IEA, GO:0070509=ISS, GO:0046785=ISS, GO:0047484=IEA, GO:0010977=ISS, GO:0007043=ISS, GO:0016021=NAS, GO:0030864=ISS, GO:0005925=ISS, GO:0005034=IEA} actin cytoskeleton reorganization, actin filament organization, calcium ion import, calcium ion transport, cell death, cell volume homeostasis, cell-cell junction assembly, cellular calcium ion homeostasis, cellular hypotonic response, cortical microtubule organization, elevation of cytosolic calcium ion concentration, hyperosmotic salinity response, microtubule polymerization, negative regulation of neuron projection development, osmosensory signaling pathway, positive regulation of microtubule depolymerization, regulation of response to osmotic stress, response to mechanical stimulus, vasopressin secretion adherens junction, cilium, cortical actin cytoskeleton, cytoplasmic microtubule, filopodium, focal adhesion, growth cone, integral to membrane, lamellipodium, plasma membrane, ruffle membrane ATP binding, SH2 domain binding, actin binding, actin filament binding, alpha-tubulin binding, beta-tubulin binding, calcium channel activity, calmodulin binding, cation channel activity, microtubule binding, osmosensor activity, protein kinase C binding, protein kinase binding Human UniProtKB:Q9ERZ8 TRPV5 UniProtKB UniProtKB {GO:0005516=GO_REF:0000037, GO:0016324=GO_REF:0000039, GO:0005262=GO_REF:0000024, GO:0051262=GO_REF:0000024, GO:0005887=PMID:15489237, GO:0006816=GO_REF:0000024, GO:0016021=GO_REF:0000038} Q9NQA5 Transient receptor potential cation channel subfamily V member 5 protein 20050506 {GO:0005516=IEA, GO:0016324=IEA, GO:0005262=ISS, GO:0051262=ISS, GO:0005887=IDA, GO:0006816=ISS, GO:0016021=IEA} calcium ion transport, protein tetramerization apical plasma membrane, integral to membrane, integral to plasma membrane calcium channel activity, calmodulin binding Human UniProtKB:P69744 TRPV6 UniProtKB UniProtKB {GO:0017158=PMID:11278579, GO:0005516=PMID:11278579, GO:0005262=PMID:15184369, GO:0005887=PMID:11278579, GO:0006816=PMID:11278579, GO:0016021=GO_REF:0000002} Q9H1D0 Transient receptor potential cation channel subfamily V member 6 protein 20050504 {GO:0017158=NAS, GO:0005516=IDA, GO:0005262=IDA, GO:0005887=TAS, GO:0006816=NAS, GO:0016021=IEA} calcium ion transport, regulation of calcium ion-dependent exocytosis integral to membrane, integral to plasma membrane calcium channel activity, calmodulin binding Human TRRAP HPA UniProtKB {GO:0005515=PMID:21150319, GO:0003712=PMID:11418595, GO:0016578=PMID:18206972, GO:0005667=GO_REF:0000019, GO:0006355=GO_REF:0000019, GO:0007093=GO_REF:0000019, GO:0016573=PMID:10966108, GO:0030914=PMID:11564863, GO:0003713=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037, GO:0033276=PMID:10373431, GO:0000125=PMID:9885574, GO:0043967=PMID:14966270, GO:0043968=PMID:14966270, GO:0035267=PMID:14966270, GO:0016773=GO_REF:0000002} Q9Y4A5 Transformation/transcription domain-associated protein protein 20110516 {GO:0005515=IPI, GO:0003712=IDA, GO:0016578=IDA, GO:0005667=IEA, GO:0006355=IEA, GO:0007093=IEA, GO:0016573=NAS, GO:0030914=IDA, GO:0003713=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0006351=IEA, GO:0033276=IDA, GO:0000125=NAS, GO:0043967=IDA, GO:0043968=IDA, GO:0035267=IDA, GO:0016773=IEA} histone H2A acetylation, histone H4 acetylation, histone acetylation, histone deubiquitination, mitotic cell cycle checkpoint, regulation of transcription, DNA-dependent, transcription, DNA-dependent NuA4 histone acetyltransferase complex, PCAF complex, STAGA complex, nucleolus, nucleus, transcription factor TFTC complex, transcription factor complex phosphotransferase activity, alcohol group as acceptor, protein binding, transcription coactivator activity, transcription cofactor activity NOT Human TRUB1 UniProtKB UniProtKB {GO:0009982=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0001522=GO_REF:0000002, GO:0008033=GO_REF:0000037} Q8WWH5 Probable tRNA pseudouridine synthase 1 protein 20130413 {GO:0009982=IEA, GO:0003723=IEA, GO:0001522=IEA, GO:0008033=IEA} pseudouridine synthesis, tRNA processing RNA binding, pseudouridine synthase activity Human UniProtKB-KW:KW-0819 TRUB2 UniProtKB UniProtKB {GO:0009982=GO_REF:0000002, GO:0006396=GO_REF:0000002, GO:0003723=GO_REF:0000002, GO:0001522=GO_REF:0000002, GO:0008033=GO_REF:0000037} O95900 Probable tRNA pseudouridine synthase 2 protein 20130413 {GO:0009982=IEA, GO:0006396=IEA, GO:0003723=IEA, GO:0001522=IEA, GO:0008033=IEA} RNA processing, pseudouridine synthesis, tRNA processing RNA binding, pseudouridine synthase activity Human UniProtKB-KW:KW-0819 TSC1 IntAct UniProtKB {GO:0008286=Reactome:REACT_498, GO:0005515=PMID:20368287, GO:0017148=PMID:17308101, GO:0045859=GO_REF:0000019, GO:0032007=PMID:17308101, GO:0008285=PMID:10915759, GO:0021987=GO_REF:0000019, GO:0005884=PMID:10806479, GO:0051492=PMID:10806479, GO:0051087=PMID:10585443, GO:0051894=PMID:10806479, GO:0051291=GO_REF:0000019, GO:0005829=Reactome:REACT_21348, GO:0043231=GO_REF:0000019, GO:0030426=GO_REF:0000019, GO:0006407=PMID:17308101, GO:0005737=PMID:9580671, GO:0007050=Reactome:REACT_21387, GO:0006813=GO_REF:0000019, GO:0055007=GO_REF:0000019, GO:0005938=PMID:10806479, GO:0030695=GO_REF:0000019, GO:0032868=PMID:16996505, GO:0001822=GO_REF:0000019, GO:0042552=GO_REF:0000019, GO:0050821=PMID:11175345, GO:0001843=GO_REF:0000019, GO:0032862=PMID:10806479, GO:0006417=PMID:17308101, GO:0030027=PMID:10806479, GO:0032794=GO_REF:0000019, GO:0043234=PMID:10585443, GO:0021766=GO_REF:0000019, GO:0045792=GO_REF:0000019, GO:0033596=PMID:9580671, GO:0047485=PMID:10806479, GO:0007160=PMID:10806479, GO:0050808=GO_REF:0000019, GO:0016020=PMID:16636147, GO:0030030=GO_REF:0000019, GO:0001952=PMID:10806479, GO:0043666=PMID:17308101} Q92574 Hamartin protein 20130415 {GO:0008286=TAS, GO:0005515=IPI, GO:0017148=IMP, GO:0045859=IEA, GO:0032007=IMP, GO:0008285=IMP, GO:0021987=IEA, GO:0005884=IDA, GO:0051492=IDA, GO:0051087=IPI, GO:0051894=IDA, GO:0051291=IEA, GO:0005829=TAS, GO:0043231=IEA, GO:0030426=IEA, GO:0006407=IMP, GO:0005737=IDA, GO:0007050=TAS, GO:0006813=IEA, GO:0055007=IEA, GO:0005938=IDA, GO:0030695=IEA, GO:0032868=IDA, GO:0001822=IEA, GO:0042552=IEA, GO:0050821=IDA, GO:0001843=IEA, GO:0032862=IDA, GO:0006417=IDA, GO:0030027=IDA, GO:0032794=IEA, GO:0043234=IDA, GO:0021766=IEA, GO:0045792=IEA, GO:0033596=IDA, GO:0047485=IPI, GO:0007160=IMP, GO:0050808=IEA, GO:0016020=IDA, GO:0030030=IEA, GO:0001952=IMP, GO:0043666=IMP} activation of Rho GTPase activity, cardiac muscle cell differentiation, cell cycle arrest, cell projection organization, cell-matrix adhesion, cerebral cortex development, hippocampus development, insulin receptor signaling pathway, kidney development, myelination, negative regulation of TOR signaling cascade, negative regulation of cell proliferation, negative regulation of cell size, negative regulation of translation, neural tube closure, positive regulation of focal adhesion assembly, potassium ion transport, protein heterooligomerization, protein stabilization, rRNA export from nucleus, regulation of cell-matrix adhesion, regulation of phosphoprotein phosphatase activity, regulation of protein kinase activity, regulation of stress fiber assembly, regulation of translation, response to insulin stimulus, synapse organization TSC1-TSC2 complex, actin filament, cell cortex, cytoplasm, cytosol, growth cone, intracellular membrane-bounded organelle, lamellipodium, membrane, protein complex GTPase activating protein binding, GTPase regulator activity, chaperone binding, protein N-terminus binding, protein binding Human UniProtKB:Q16539 TSC2 HPA UniProtKB {GO:0005515=PMID:20169165, GO:0050680=GO_REF:0000019, GO:0006606=GO_REF:0000024, GO:0042803=PMID:10585443, GO:0007507=GO_REF:0000024, GO:0007173=Reactome:REACT_9417, GO:0030100=GO_REF:0000024, GO:0043025=GO_REF:0000019, GO:0051260=GO_REF:0000019, GO:0044430=GO_REF:0000019, GO:0005794=PMID:8806680, GO:0046982=GO_REF:0000019, GO:0019902=PMID:19389623, GO:0001843=GO_REF:0000024, GO:0006953=GO_REF:0000019, GO:0014067=GO_REF:0000024, GO:0014065=GO_REF:0000019, GO:0006897=PMID:9045618, GO:0045792=GO_REF:0000033, GO:0033596=PMID:9580671, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0030030=GO_REF:0000019, GO:0043491=GO_REF:0000024, GO:0051898=GO_REF:0000024, GO:0008286=Reactome:REACT_498, GO:0032007=GO_REF:0000033, GO:0048471=PMID:8806680, GO:0008285=GO_REF:0000024, GO:0030178=GO_REF:0000033, GO:0005634=PMID:17114346, GO:0051291=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0030426=GO_REF:0000019, GO:0005829=Reactome:REACT_147764, GO:0071889=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0008104=GO_REF:0000024, GO:0043407=GO_REF:0000019, GO:0051726=GO_REF:0000033, GO:0007050=Reactome:REACT_21387, GO:0016192=PMID:9045618, GO:0051056=GO_REF:0000002, GO:0001666=GO_REF:0000019, GO:0048011=Reactome:REACT_11061, GO:0048015=Reactome:REACT_12464, GO:0046626=GO_REF:0000024, GO:0050918=GO_REF:0000024, GO:0016020=PMID:16636147, GO:0005901=GO_REF:0000019, GO:0048009=GO_REF:0000024, GO:0006469=GO_REF:0000024, GO:0005096=PMID:9045618} P49815 Tuberin protein 20101115 {GO:0005515=IPI, GO:0050680=IEA, GO:0006606=ISS, GO:0042803=IPI, GO:0007507=ISS, GO:0007173=TAS, GO:0030100=ISS, GO:0043025=IEA, GO:0051260=IEA, GO:0044430=IEA, GO:0005794=IDA, GO:0046982=IEA, GO:0019902=IDA, GO:0001843=ISS, GO:0006953=IEA, GO:0014067=ISS, GO:0014065=IEA, GO:0006897=TAS, GO:0045792=IBA, GO:0033596=IDA, GO:0008543=TAS, GO:0045087=TAS, GO:0030030=IEA, GO:0043491=ISS, GO:0051898=ISS, GO:0008286=TAS, GO:0032007=IBA, GO:0048471=IDA, GO:0008285=ISS, GO:0030178=IBA, GO:0005634=IDA, GO:0051291=IEA, GO:0030425=IEA, GO:0030426=IEA, GO:0005829=TAS, GO:0071889=IEA, GO:0005737=IDA, GO:0008104=ISS, GO:0043407=IEA, GO:0051726=IBA, GO:0007050=TAS, GO:0016192=TAS, GO:0051056=IEA, GO:0001666=IEA, GO:0048011=TAS, GO:0048015=TAS, GO:0046626=ISS, GO:0050918=ISS, GO:0016020=IDA, GO:0005901=IEA, GO:0048009=ISS, GO:0006469=ISS, GO:0005096=IDA} acute-phase response, cell cycle arrest, cell projection organization, endocytosis, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, heart development, innate immune response, insulin receptor signaling pathway, insulin-like growth factor receptor signaling pathway, negative regulation of MAP kinase activity, negative regulation of TOR signaling cascade, negative regulation of Wnt receptor signaling pathway, negative regulation of cell proliferation, negative regulation of cell size, negative regulation of epithelial cell proliferation, negative regulation of phosphatidylinositol 3-kinase cascade, negative regulation of protein kinase B signaling cascade, negative regulation of protein kinase activity, neural tube closure, neurotrophin TRK receptor signaling pathway, phosphatidylinositol 3-kinase cascade, phosphatidylinositol-mediated signaling, positive chemotaxis, protein heterooligomerization, protein homooligomerization, protein import into nucleus, protein kinase B signaling cascade, protein localization, regulation of cell cycle, regulation of endocytosis, regulation of insulin receptor signaling pathway, regulation of small GTPase mediated signal transduction, response to hypoxia, vesicle-mediated transport Golgi apparatus, TSC1-TSC2 complex, caveola, cytoplasm, cytoskeletal part, cytosol, dendrite, growth cone, membrane, neuronal cell body, nucleus, perinuclear region of cytoplasm 14-3-3 protein binding, GTPase activator activity, phosphatase binding, protein binding, protein heterodimerization activity, protein homodimerization activity Human TSC22D1 PINC UniProtKB {GO:0043066=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0043065=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0006366=PMID:9022669, GO:0005634=GO_REF:0000039} Q15714 TSC22 domain family protein 1 protein 20030904 {GO:0043066=IEA, GO:0008284=IEA, GO:0005737=IEA, GO:0043065=IEA, GO:0003700=IEA, GO:0006366=TAS, GO:0005634=IEA} negative regulation of apoptotic process, positive regulation of apoptotic process, positive regulation of cell proliferation, transcription from RNA polymerase II promoter cytoplasm, nucleus sequence-specific DNA binding transcription factor activity Human TSC22D2 ENSEMBL UniProtKB {GO:0003700=GO_REF:0000002, GO:0006970=GO_REF:0000019} O75157 TSC22 domain family protein 2 protein 20130413 {GO:0003700=IEA, GO:0006970=IEA} response to osmotic stress sequence-specific DNA binding transcription factor activity Human Ensembl:ENSMUSP00000096688 TSC22D3 Reactome UniProtKB {GO:0007589=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0006355=PMID:8982256, GO:0003700=GO_REF:0000002, GO:0043426=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0006970=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0048642=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0005829=Reactome:REACT_160256, GO:0005737=GO_REF:0000019, GO:0034220=Reactome:REACT_25300} Q99576 TSC22 domain family protein 3 protein 20121129 {GO:0007589=IEA, GO:0043066=IEA, GO:0006355=TAS, GO:0003700=IEA, GO:0043426=IEA, GO:0005634=IEA, GO:0006970=IEA, GO:0000122=IEA, GO:0048642=IEA, GO:0055085=TAS, GO:0005829=TAS, GO:0005737=IEA, GO:0034220=TAS} body fluid secretion, ion transmembrane transport, negative regulation of apoptotic process, negative regulation of skeletal muscle tissue development, negative regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, response to osmotic stress, transmembrane transport cytoplasm, cytosol, nucleus MRF binding, sequence-specific DNA binding transcription factor activity Human TSC22D4 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0006355=GO_REF:0000029, GO:0005737=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0006970=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0045892=GO_REF:0000029, GO:0006351=GO_REF:0000037} Q9Y3Q8 TSC22 domain family protein 4 protein 20130415 {GO:0005515=IPI, GO:0006355=NAS, GO:0005737=IEA, GO:0003700=IEA, GO:0006970=IEA, GO:0005634=IEA, GO:0045892=NAS, GO:0006351=IEA} negative regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, response to osmotic stress, transcription, DNA-dependent cytoplasm, nucleus protein binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:Q14145 TSEN15 UniProtKB UniProtKB {GO:0006397=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0008033=GO_REF:0000037} Q8WW01 tRNA-splicing endonuclease subunit Sen15 protein 20130413 {GO:0006397=IEA, GO:0005730=IEA, GO:0008033=IEA} mRNA processing, tRNA processing nucleolus Human UniProtKB-SubCell:SL-0188 TSEN2 HPA UniProtKB {GO:0006397=GO_REF:0000037, GO:0006388=PMID:17495927, GO:0004518=GO_REF:0000002, GO:0005813=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0000214=GO_REF:0000002, GO:0000213=GO_REF:0000003} Q8NCE0 tRNA-splicing endonuclease subunit Sen2 protein 20111111 {GO:0006397=IEA, GO:0006388=IDA, GO:0004518=IEA, GO:0005813=IDA, GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0000214=IEA, GO:0000213=IEA} mRNA processing, tRNA splicing, via endonucleolytic cleavage and ligation centrosome, cytoplasm, nucleolus, nucleus, tRNA-intron endonuclease complex nuclease activity, nucleic acid binding, tRNA-intron endonuclease activity Human TSEN34 UniProtKB UniProtKB {GO:0006397=GO_REF:0000037, GO:0006388=GO_REF:0000002, GO:0005730=GO_REF:0000039, GO:0000214=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0000379=GO_REF:0000002, GO:0000213=GO_REF:0000003} Q9BSV6 tRNA-splicing endonuclease subunit Sen34 protein 20130413 {GO:0006397=IEA, GO:0006388=IEA, GO:0005730=IEA, GO:0000214=IEA, GO:0003676=IEA, GO:0000379=IEA, GO:0000213=IEA} mRNA processing, tRNA splicing, via endonucleolytic cleavage and ligation, tRNA-type intron splice site recognition and cleavage nucleolus, tRNA-intron endonuclease complex nucleic acid binding, tRNA-intron endonuclease activity Human UniProtKB-SubCell:SL-0188 TSEN54 UniProtKB UniProtKB {GO:0006388=PMID:17495927, GO:0006397=GO_REF:0000037, GO:0005730=GO_REF:0000039} Q7Z6J9 tRNA-splicing endonuclease subunit Sen54 protein 20090421 {GO:0006388=IDA, GO:0006397=IEA, GO:0005730=IEA} mRNA processing, tRNA splicing, via endonucleolytic cleavage and ligation nucleolus Human TSFM HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005622=GO_REF:0000002, GO:0032784=PMID:7615523, GO:0005634=GO_REF:0000052, GO:0003746=GO_REF:0000020, GO:0006414=PMID:7615523} P43897 Elongation factor Ts, mitochondrial protein 20080205 {GO:0005739=IDA, GO:0005622=IEA, GO:0032784=TAS, GO:0005634=IDA, GO:0003746=IEA, GO:0006414=TAS} regulation of DNA-dependent transcription, elongation, translational elongation intracellular, mitochondrion, nucleus translation elongation factor activity Human TSG101 HPA UniProtKB {GO:0005515=PMID:19060904, GO:0022415=Reactome:REACT_6361, GO:0043130=PMID:15611048, GO:0008285=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0046755=PMID:15126635, GO:0015031=GO_REF:0000037, GO:0001558=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0016197=Reactome:REACT_27258, GO:0016032=Reactome:REACT_6256, GO:0007050=GO_REF:0000019, GO:0031625=PMID:17229889, GO:0005770=PMID:15126635, GO:0003714=GO_REF:0000019, GO:0005771=PMID:15611048, GO:0019082=Reactome:REACT_115860, GO:0005730=GO_REF:0000052, GO:0019068=Reactome:REACT_6818, GO:0003677=PMID:10888872, GO:0046788=Reactome:REACT_115893, GO:0030216=GO_REF:0000019, GO:0031902=GO_REF:0000039, GO:0045892=GO_REF:0000019, GO:0043162=PMID:15611048, GO:0016044=Reactome:REACT_11123, GO:0010008=Reactome:REACT_115855, GO:0005769=PMID:17229889, GO:0006464=GO_REF:0000002, GO:0051301=GO_REF:0000037, GO:0048306=PMID:19520058} Q99816 Tumor susceptibility gene 101 protein protein 20080205 {GO:0005515=IPI, GO:0022415=TAS, GO:0043130=TAS, GO:0008285=IEA, GO:0005886=IDA, GO:0046755=IMP, GO:0015031=IEA, GO:0001558=IEA, GO:0005737=IDA, GO:0016197=TAS, GO:0016032=TAS, GO:0007050=IEA, GO:0031625=IPI, GO:0005770=IMP, GO:0003714=IEA, GO:0005771=TAS, GO:0019082=TAS, GO:0005730=IDA, GO:0019068=TAS, GO:0003677=TAS, GO:0046788=TAS, GO:0030216=IEA, GO:0031902=IEA, GO:0045892=IEA, GO:0043162=IDA, GO:0016044=TAS, GO:0010008=TAS, GO:0005769=IDA, GO:0006464=IEA, GO:0051301=IEA, GO:0048306=IPI} cell cycle arrest, cell division, cellular membrane organization, cellular protein modification process, egress of virus within host cell, endosomal transport, keratinocyte differentiation, negative regulation of cell proliferation, negative regulation of transcription, DNA-dependent, non-lytic virus budding, protein transport, regulation of cell growth, ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway, viral protein processing, viral reproduction, viral reproductive process, virion assembly cytoplasm, early endosome, endosome membrane, late endosome, late endosome membrane, multivesicular body, nucleolus, plasma membrane DNA binding, calcium-dependent protein binding, protein binding, transcription corepressor activity, ubiquitin binding, ubiquitin protein ligase binding Human TSGA10 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0043005=GO_REF:0000019, GO:0031965=GO_REF:0000039, GO:0005737=GO_REF:0000039, GO:0030031=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0007283=PMID:11179690} Q9BZW7 Testis-specific gene 10 protein protein 20061026 {GO:0003674=ND, GO:0043005=IEA, GO:0031965=IEA, GO:0005737=IEA, GO:0030031=IEA, GO:0005575=ND, GO:0007283=TAS} cell projection assembly, spermatogenesis cellular_component, cytoplasm, neuron projection, nuclear membrane molecular_function Human TSHB Reactome UniProtKB {GO:0051592=GO_REF:0000019, GO:0043627=GO_REF:0000019, GO:0016486=Reactome:REACT_15452, GO:0007186=PMID:2792087, GO:0005179=GO_REF:0000037, GO:0033189=GO_REF:0000019, GO:0007267=PMID:2792087, GO:0005576=Reactome:REACT_22268, GO:0044267=Reactome:REACT_17015, GO:0009653=PMID:2792087} P01222 Thyrotropin subunit beta protein 20130301 {GO:0051592=IEA, GO:0043627=IEA, GO:0016486=TAS, GO:0007186=TAS, GO:0005179=IEA, GO:0033189=IEA, GO:0007267=TAS, GO:0005576=TAS, GO:0044267=TAS, GO:0009653=TAS} G-protein coupled receptor signaling pathway, anatomical structure morphogenesis, cell-cell signaling, cellular protein metabolic process, peptide hormone processing, response to calcium ion, response to estrogen stimulus, response to vitamin A extracellular region hormone activity Human TSHR ENSEMBL UniProtKB {GO:0005515=PMID:15775968, GO:0008344=GO_REF:0000019, GO:0008284=PMID:7920658, GO:0005886=GO_REF:0000019, GO:0007267=PMID:7920658, GO:0016500=GO_REF:0000002, GO:0040012=GO_REF:0000019, GO:0007186=PMID:8552586, GO:0005887=PMID:8552586, GO:0007187=PMID:8552586, GO:0004996=GO_REF:0000019, GO:0030183=GO_REF:0000019, GO:0007189=GO_REF:0000019, GO:0040018=GO_REF:0000019, GO:0016021=GO_REF:0000002} Q0VAP8 TSHR protein protein 20130413 {GO:0005515=IPI, GO:0008344=IEA, GO:0008284=TAS, GO:0005886=IEA, GO:0007267=TAS, GO:0016500=IEA, GO:0040012=IEA, GO:0007186=TAS, GO:0005887=TAS, GO:0007187=TAS, GO:0004996=IEA, GO:0030183=IEA, GO:0007189=IEA, GO:0040018=IEA, GO:0016021=IEA} B cell differentiation, G-protein coupled receptor signaling pathway, G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, adenylate cyclase-activating G-protein coupled receptor signaling pathway, adult locomotory behavior, cell-cell signaling, positive regulation of cell proliferation, positive regulation of multicellular organism growth, regulation of locomotion integral to membrane, integral to plasma membrane, plasma membrane protein binding, protein-hormone receptor activity, thyroid-stimulating hormone receptor activity Human Ensembl:ENSMUSP00000021346 TSHZ1 HPA UniProtKB {GO:0043565=GO_REF:0000002, GO:0010468=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0042474=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0060023=GO_REF:0000019} Q6ZSZ6 Teashirt homolog 1 protein 20080205 {GO:0043565=IEA, GO:0010468=IEA, GO:0003700=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0042474=IEA, GO:0009952=IEA, GO:0006351=IEA, GO:0060023=IEA} anterior/posterior pattern specification, middle ear morphogenesis, regulation of gene expression, soft palate development, transcription, DNA-dependent nucleolus, nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding NOT Human TSHZ2 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q9NRE2 Teashirt homolog 2 protein 20130413 {GO:0043565=IEA, GO:0003700=IEA, GO:0005634=IEA, GO:0007275=IEA, GO:0008270=IEA, GO:0006351=IEA} multicellular organismal development, transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB-SubCell:SL-0191 TSHZ3 UniProtKB UniProtKB {GO:0005515=PMID:19343227, GO:0001656=GO_REF:0000019, GO:0001657=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0030324=GO_REF:0000019, GO:0005634=PMID:19343227, GO:0072105=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0030426=GO_REF:0000039, GO:0072193=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0005739=GO_REF:0000019, GO:0002087=GO_REF:0000024, GO:0050881=GO_REF:0000019, GO:0003682=PMID:19343227, GO:0072195=GO_REF:0000019, GO:0060993=GO_REF:0000019, GO:0051152=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0050975=GO_REF:0000019, GO:0045892=PMID:19343227} Q63HK5 Teashirt homolog 3 protein 20100817 {GO:0005515=IPI, GO:0001656=IEA, GO:0001657=IEA, GO:0003700=IEA, GO:0030324=IEA, GO:0005634=IDA, GO:0072105=IEA, GO:0001701=IEA, GO:0006351=IEA, GO:0030426=IEA, GO:0072193=IEA, GO:0043565=IEA, GO:0005739=IEA, GO:0002087=ISS, GO:0050881=IEA, GO:0003682=IDA, GO:0072195=IEA, GO:0060993=IEA, GO:0051152=IEA, GO:0008270=IEA, GO:0050975=IEA, GO:0045892=IDA} in utero embryonic development, kidney morphogenesis, kidney smooth muscle cell differentiation, lung development, metanephros development, musculoskeletal movement, negative regulation of transcription, DNA-dependent, positive regulation of smooth muscle cell differentiation, regulation of respiratory gaseous exchange by neurological system process, sensory perception of touch, transcription, DNA-dependent, ureter smooth muscle cell differentiation, ureteric bud development, ureteric peristalsis growth cone, mitochondrion, nucleus chromatin binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB:Q8CGV9 TSKS IntAct UniProtKB {GO:0005515=PMID:15044604, GO:0019901=PMID:18533145, GO:0005814=PMID:18495105, GO:0010923=PMID:19389623} Q9UJT2 Testis-specific serine kinase substrate protein 20130415 {GO:0005515=IPI, GO:0019901=IPI, GO:0005814=IDA, GO:0010923=IDA} negative regulation of phosphatase activity centriole protein binding, protein kinase binding Human UniProtKB:Q96PF2 TSKU UniProtKB UniProtKB {GO:0021960=GO_REF:0000019, GO:0021540=GO_REF:0000019, GO:0021670=GO_REF:0000019, GO:0005576=GO_REF:0000039} Q8WUA8 Tsukushin protein 20130413 {GO:0021960=IEA, GO:0021540=IEA, GO:0021670=IEA, GO:0005576=IEA} anterior commissure morphogenesis, corpus callosum morphogenesis, lateral ventricle development extracellular region Human UniProtKB-SubCell:SL-0243 TSLP ENSEMBL UniProtKB {GO:0005615=GO_REF:0000037, GO:0005125=GO_REF:0000019} Q969D9 Thymic stromal lymphopoietin protein 20130413 {GO:0005615=IEA, GO:0005125=IEA} extracellular space cytokine activity Human Ensembl:ENSMUSP00000025237 TSN IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0043565=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0004519=GO_REF:0000037, GO:0006310=PMID:7663511, GO:0005634=GO_REF:0000039, GO:0003729=GO_REF:0000019, GO:0003677=PMID:7663511} Q15631 Translin protein 20130415 {GO:0005515=IPI, GO:0043565=IEA, GO:0005737=IEA, GO:0004519=IEA, GO:0006310=TAS, GO:0005634=IEA, GO:0003729=IEA, GO:0003677=TAS} DNA recombination cytoplasm, nucleus DNA binding, endonuclease activity, mRNA binding, protein binding, sequence-specific DNA binding Human UniProtKB:Q14161 TSNAX GOC UniProtKB {GO:0048471=GO_REF:0000039, GO:0005794=GO_REF:0000039, GO:0031687=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0007283=GO_REF:0000037, GO:0015031=PMID:9013868, GO:0032403=GO_REF:0000019, GO:0003677=PMID:9013868, GO:0030154=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0008565=PMID:9013868} Q99598 Translin-associated protein X protein 20130413 {GO:0048471=IEA, GO:0005794=IEA, GO:0031687=IEA, GO:0007275=IEA, GO:0005634=IEA, GO:0007283=IEA, GO:0015031=TAS, GO:0032403=IEA, GO:0003677=TAS, GO:0030154=IEA, GO:0046872=IEA, GO:0043565=IEA, GO:0008565=TAS} cell differentiation, multicellular organismal development, protein transport, spermatogenesis Golgi apparatus, nucleus, perinuclear region of cytoplasm A2A adenosine receptor binding, DNA binding, metal ion binding, protein complex binding, protein transporter activity, sequence-specific DNA binding Human TSNAXIP1 UniProtKB UniProtKB {GO:0048471=GO_REF:0000039, GO:0005737=GO_REF:0000019, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q2TAA8 Translin-associated factor X-interacting protein 1 protein 20130413 {GO:0048471=IEA, GO:0005737=IEA, GO:0007275=IEA, GO:0007283=IEA, GO:0030154=IEA} cell differentiation, multicellular organismal development, spermatogenesis cytoplasm, perinuclear region of cytoplasm Human UniProtKB-SubCell:SL-0198 TSPAN1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0005765=GO_REF:0000039} O60635 Tetraspanin-1 protein 20130413 {GO:0016021=IEA, GO:0005765=IEA} integral to membrane, lysosomal membrane Human UniProtKB-SubCell:SL-0157 TSPAN10 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9H1Z9 Tetraspanin-10 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TSPAN12 PINC UniProtKB {GO:0042813=GO_REF:0000024, GO:0016020=PMID:10719184, GO:0005887=GO_REF:0000024, GO:0045765=GO_REF:0000024, GO:0010842=GO_REF:0000024, GO:0016021=PMID:10719184, GO:0001525=GO_REF:0000037, GO:0007166=GO_REF:0000024} O95859 Tetraspanin-12 protein 20030904 {GO:0042813=ISS, GO:0016020=TAS, GO:0005887=ISS, GO:0045765=ISS, GO:0010842=ISS, GO:0016021=TAS, GO:0001525=IEA, GO:0007166=ISS} angiogenesis, cell surface receptor signaling pathway, regulation of angiogenesis, retina layer formation integral to membrane, integral to plasma membrane, membrane Wnt-activated receptor activity Human TSPAN13 PINC UniProtKB {GO:0016020=PMID:10719184, GO:0005887=PMID:10719184} O95857 Tetraspanin-13 protein 20030904 {GO:0016020=TAS, GO:0005887=TAS} integral to plasma membrane, membrane Human TSPAN14 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8NG11 Tetraspanin-14 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TSPAN15 PINC UniProtKB {GO:0016020=PMID:10719184, GO:0005887=PMID:10719184, GO:0016021=GO_REF:0000038} O95858 Tetraspanin-15 protein 20030904 {GO:0016020=TAS, GO:0005887=TAS, GO:0016021=IEA} integral to membrane, integral to plasma membrane, membrane Human TSPAN17 UniProtKB UniProtKB {GO:0004842=PMID:10531035, GO:0016567=PMID:10531035, GO:0000151=PMID:10531035, GO:0016021=GO_REF:0000037} Q96FV3 Tetraspanin-17 protein 20050308 {GO:0004842=NAS, GO:0016567=NAS, GO:0000151=NAS, GO:0016021=IEA} protein ubiquitination integral to membrane, ubiquitin ligase complex ubiquitin-protein ligase activity Human TSPAN2 ENSEMBL UniProtKB {GO:0007420=GO_REF:0000019, GO:0043209=GO_REF:0000019, GO:0016021=GO_REF:0000037} O60636 Tetraspanin-2 protein 20130413 {GO:0007420=IEA, GO:0043209=IEA, GO:0016021=IEA} brain development integral to membrane, myelin sheath Human Ensembl:ENSRNOP00000033076 TSPAN3 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} O60637 Tetraspanin-3 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TSPAN31 PINC UniProtKB {GO:0008284=PMID:8134123, GO:0016020=PMID:8134123, GO:0005887=PMID:8134123, GO:0016021=GO_REF:0000002} Q12999 Tetraspanin-31 protein 20030904 {GO:0008284=TAS, GO:0016020=TAS, GO:0005887=TAS, GO:0016021=IEA} positive regulation of cell proliferation integral to membrane, integral to plasma membrane, membrane Human TSPAN4 PINC UniProtKB {GO:0006461=PMID:9360996, GO:0005886=PMID:9360996, GO:0005887=PMID:9360996, GO:0016021=GO_REF:0000038} O14817 Tetraspanin-4 protein 20030904 {GO:0006461=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0016021=IEA} protein complex assembly integral to membrane, integral to plasma membrane, plasma membrane Human TSPAN5 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} P62079 Tetraspanin-5 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 TSPAN6 GOC UniProtKB {GO:0007165=PMID:12761501, GO:0004871=PMID:12761501, GO:0016021=GO_REF:0000037, GO:0043123=PMID:12761501} O43657 Tetraspanin-6 protein 20130413 {GO:0007165=IMP, GO:0004871=IMP, GO:0016021=IEA, GO:0043123=IMP} positive regulation of I-kappaB kinase/NF-kappaB cascade, signal transduction integral to membrane signal transducer activity Human TSPAN7 PINC UniProtKB {GO:0005887=PMID:8420826, GO:0019048=GO_REF:0000037, GO:0016021=GO_REF:0000038} P41732 Tetraspanin-7 protein 20030904 {GO:0005887=TAS, GO:0019048=IEA, GO:0016021=IEA} virus-host interaction integral to membrane, integral to plasma membrane Human TSPAN9 PINC UniProtKB {GO:0016020=PMID:10719184, GO:0005887=PMID:10719184, GO:0016021=GO_REF:0000038} O75954 Tetraspanin-9 protein 20030904 {GO:0016020=TAS, GO:0005887=TAS, GO:0016021=IEA} integral to membrane, integral to plasma membrane, membrane Human TSPO HGNC UniProtKB {GO:0006820=PMID:16822554, GO:0071294=GO_REF:0000019, GO:0006694=GO_REF:0000019, GO:0030325=GO_REF:0000019, GO:0008347=GO_REF:0000019, GO:0008283=PMID:16822554, GO:0051928=GO_REF:0000019, GO:0006626=PMID:1326278, GO:0005741=GO_REF:0000019, GO:0050810=GO_REF:0000019, GO:0060242=GO_REF:0000019, GO:0010042=GO_REF:0000019, GO:0051901=GO_REF:0000019, GO:0015485=PMID:16822554, GO:0045019=GO_REF:0000019, GO:0014012=GO_REF:0000019, GO:0005497=GO_REF:0000019, GO:0008202=PMID:16822554, GO:0010940=GO_REF:0000019, GO:0032374=PMID:16822554, GO:0071476=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0006915=PMID:16822554, GO:0032720=GO_REF:0000019, GO:0060252=GO_REF:0000019, GO:0060253=GO_REF:0000019, GO:0010266=GO_REF:0000019, GO:0033574=GO_REF:0000019, GO:0006783=PMID:16822554, GO:0071222=GO_REF:0000019, GO:0032570=GO_REF:0000019, GO:0008503=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:2000379=GO_REF:0000019, GO:0048266=GO_REF:0000019} P30536 Translocator protein protein 20071018 {GO:0006820=TAS, GO:0071294=IEA, GO:0006694=IEA, GO:0030325=IEA, GO:0008347=IEA, GO:0008283=TAS, GO:0051928=IEA, GO:0006626=TAS, GO:0005741=IEA, GO:0050810=IEA, GO:0060242=IEA, GO:0010042=IEA, GO:0051901=IEA, GO:0015485=TAS, GO:0045019=IEA, GO:0014012=IEA, GO:0005497=IEA, GO:0008202=TAS, GO:0010940=IEA, GO:0032374=TAS, GO:0071476=IEA, GO:0043065=IEA, GO:0042493=IEA, GO:0007568=IEA, GO:0006915=TAS, GO:0032720=IEA, GO:0060252=IEA, GO:0060253=IEA, GO:0010266=IEA, GO:0033574=IEA, GO:0006783=TAS, GO:0071222=IEA, GO:0032570=IEA, GO:0008503=IEA, GO:0016021=IEA, GO:2000379=IEA, GO:0048266=IEA} adrenal gland development, aging, anion transport, apoptotic process, behavioral response to pain, cell proliferation, cellular hypotonic response, cellular response to lipopolysaccharide, cellular response to zinc ion, contact inhibition, glial cell migration, heme biosynthetic process, negative regulation of glial cell proliferation, negative regulation of nitric oxide biosynthetic process, negative regulation of tumor necrosis factor production, peripheral nervous system axon regeneration, positive regulation of apoptotic process, positive regulation of calcium ion transport, positive regulation of glial cell proliferation, positive regulation of mitochondrial depolarization, positive regulation of necrotic cell death, positive regulation of reactive oxygen species metabolic process, protein targeting to mitochondrion, regulation of cholesterol transport, regulation of steroid biosynthetic process, response to drug, response to manganese ion, response to progesterone stimulus, response to testosterone stimulus, response to vitamin B1, steroid biosynthetic process, steroid metabolic process integral to membrane, mitochondrial outer membrane androgen binding, benzodiazepine receptor activity, cholesterol binding Human TSPY1 PINC UniProtKB {GO:0003674=GO_REF:0000015, GO:0007506=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0008283=PMID:8923009, GO:0006334=GO_REF:0000002, GO:0007548=PMID:1284595, GO:0005634=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0007283=GO_REF:0000037, GO:0030154=GO_REF:0000037} Q01534 Testis-specific Y-encoded protein 1 protein 20030904 {GO:0003674=ND, GO:0007506=IEA, GO:0005737=IEA, GO:0008283=TAS, GO:0006334=IEA, GO:0007548=TAS, GO:0005634=IEA, GO:0005575=ND, GO:0007283=IEA, GO:0030154=IEA} cell differentiation, cell proliferation, gonadal mesoderm development, nucleosome assembly, sex differentiation, spermatogenesis cellular_component, cytoplasm, nucleus molecular_function Human TSPY10 UniProtKB UniProtKB {GO:0007506=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0006334=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0007283=GO_REF:0000037, GO:0030154=GO_REF:0000037} P0CW01 Testis-specific Y-encoded protein 10 protein 20130413 {GO:0007506=IEA, GO:0005737=IEA, GO:0006334=IEA, GO:0005634=IEA, GO:0007283=IEA, GO:0030154=IEA} cell differentiation, gonadal mesoderm development, nucleosome assembly, spermatogenesis cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 TSPY2 UniProtKB UniProtKB {GO:0007506=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0006334=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0007283=GO_REF:0000037, GO:0030154=GO_REF:0000037} A6NKD2 Testis-specific Y-encoded protein 2 protein 20130413 {GO:0007506=IEA, GO:0005737=IEA, GO:0006334=IEA, GO:0005634=IEA, GO:0007283=IEA, GO:0030154=IEA} cell differentiation, gonadal mesoderm development, nucleosome assembly, spermatogenesis cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 TSPY3 UniProtKB UniProtKB {GO:0007506=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0006334=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0007283=GO_REF:0000037, GO:0030154=GO_REF:0000037} P0CV98 Testis-specific Y-encoded protein 3 protein 20130413 {GO:0007506=IEA, GO:0005737=IEA, GO:0006334=IEA, GO:0005634=IEA, GO:0007283=IEA, GO:0030154=IEA} cell differentiation, gonadal mesoderm development, nucleosome assembly, spermatogenesis cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 TSPY4 UniProtKB UniProtKB {GO:0007506=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0006334=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0007283=GO_REF:0000037, GO:0030154=GO_REF:0000037} P0CV99 Testis-specific Y-encoded protein 4 protein 20130413 {GO:0007506=IEA, GO:0005737=IEA, GO:0006334=IEA, GO:0005634=IEA, GO:0007283=IEA, GO:0030154=IEA} cell differentiation, gonadal mesoderm development, nucleosome assembly, spermatogenesis cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 TSPY8 UniProtKB UniProtKB {GO:0007506=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0006334=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0007283=GO_REF:0000037, GO:0030154=GO_REF:0000037} P0CW00 Testis-specific Y-encoded protein 8 protein 20130413 {GO:0007506=IEA, GO:0005737=IEA, GO:0006334=IEA, GO:0005634=IEA, GO:0007283=IEA, GO:0030154=IEA} cell differentiation, gonadal mesoderm development, nucleosome assembly, spermatogenesis cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 TSPYL1 HPA UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0006334=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0005575=GO_REF:0000015} Q9H0U9 Testis-specific Y-encoded-like protein 1 protein 20110516 {GO:0003674=ND, GO:0008150=ND, GO:0005737=IDA, GO:0005730=IDA, GO:0006334=IEA, GO:0005634=IDA, GO:0005575=ND} biological_process, nucleosome assembly cellular_component, cytoplasm, nucleolus, nucleus molecular_function Human TSPYL2 HPA UniProtKB {GO:0045859=PMID:11395479, GO:0005813=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0030308=PMID:11395479, GO:0005886=GO_REF:0000052, GO:0006334=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0009966=PMID:11395479, GO:0045786=PMID:11395479, GO:0006351=GO_REF:0000037, GO:0030968=Reactome:REACT_18356, GO:0005737=GO_REF:0000052, GO:0007049=GO_REF:0000037, GO:0000182=PMID:11395479, GO:0005654=Reactome:REACT_116034, GO:0008156=PMID:11395479, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0016568=GO_REF:0000037} Q9H2G4 Testis-specific Y-encoded-like protein 2 protein 20111111 {GO:0045859=IDA, GO:0005813=IDA, GO:0006355=IEA, GO:0030308=IDA, GO:0005886=IDA, GO:0006334=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0009966=NAS, GO:0045786=NAS, GO:0006351=IEA, GO:0030968=TAS, GO:0005737=IDA, GO:0007049=IEA, GO:0000182=NAS, GO:0005654=TAS, GO:0008156=IDA, GO:0006987=TAS, GO:0044267=TAS, GO:0016568=IEA} activation of signaling protein activity involved in unfolded protein response, cell cycle, cellular protein metabolic process, chromatin modification, endoplasmic reticulum unfolded protein response, negative regulation of DNA replication, negative regulation of cell cycle, negative regulation of cell growth, nucleosome assembly, regulation of protein kinase activity, regulation of signal transduction, regulation of transcription, DNA-dependent, transcription, DNA-dependent centrosome, cytoplasm, nucleolus, nucleoplasm, nucleus, plasma membrane rDNA binding Human TSPYL4 InterPro UniProtKB {GO:0006334=GO_REF:0000002, GO:0005634=GO_REF:0000002} Q9UJ04 Testis-specific Y-encoded-like protein 4 protein 20130413 {GO:0006334=IEA, GO:0005634=IEA} nucleosome assembly nucleus Human InterPro:IPR002164 TSPYL5 IntAct UniProtKB {GO:0005515=PMID:21170034, GO:0051897=PMID:20079711, GO:0008284=PMID:21170034, GO:0031398=PMID:21170034, GO:0006334=GO_REF:0000002, GO:0005634=GO_REF:0000002, GO:0071480=PMID:20079711, GO:0040008=GO_REF:0000037} Q86VY4 Testis-specific Y-encoded-like protein 5 protein 20130415 {GO:0005515=IPI, GO:0051897=IMP, GO:0008284=IDA, GO:0031398=IDA, GO:0006334=IEA, GO:0005634=IEA, GO:0071480=IMP, GO:0040008=IEA} cellular response to gamma radiation, nucleosome assembly, positive regulation of cell proliferation, positive regulation of protein kinase B signaling cascade, positive regulation of protein ubiquitination, regulation of growth nucleus protein binding Human UniProtKB:Q93009 TSR1 UniProtKB UniProtKB {GO:0042255=GO_REF:0000024, GO:0005730=GO_REF:0000024} Q2NL82 Pre-rRNA-processing protein TSR1 homolog protein 20080201 {GO:0042255=ISS, GO:0005730=ISS} ribosome assembly nucleolus Human UniProtKB:Q08965 TSR2 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0006364=GO_REF:0000037} Q969E8 Pre-rRNA-processing protein TSR2 homolog protein 20130415 {GO:0005515=IPI, GO:0006364=IEA} rRNA processing protein binding Human UniProtKB:P62854 TSSC1 null null {} null null null null {} null null null TSSC4 null null {} null null null null {} null null null TSSK1B UniProtKB UniProtKB {GO:0000287=PMID:15733851, GO:0001669=GO_REF:0000039, GO:0031514=GO_REF:0000024, GO:0004674=PMID:19530700, GO:0007286=GO_REF:0000024, GO:0006468=PMID:15733851, GO:0007275=GO_REF:0000037, GO:0005524=PMID:15733851} Q9BXA7 Testis-specific serine/threonine-protein kinase 1 protein 20110706 {GO:0000287=IDA, GO:0001669=IEA, GO:0031514=ISS, GO:0004674=IDA, GO:0007286=ISS, GO:0006468=IDA, GO:0007275=IEA, GO:0005524=IDA} multicellular organismal development, protein phosphorylation, spermatid development acrosomal vesicle, motile cilium ATP binding, magnesium ion binding, protein serine/threonine kinase activity Human UniProtKB:Q61241 TSSK2 IntAct UniProtKB {GO:0005515=PMID:15044604, GO:0005737=GO_REF:0000024, GO:0000287=GO_REF:0000024, GO:0046777=PMID:20729278, GO:0001669=GO_REF:0000019, GO:0004674=PMID:18533145, GO:0005814=GO_REF:0000039, GO:0007286=GO_REF:0000024, GO:0006468=GO_REF:0000024, GO:0007275=GO_REF:0000037, GO:0005524=GO_REF:0000024, GO:0042802=PMID:15044604} Q96PF2 Testis-specific serine/threonine-protein kinase 2 protein 20130415 {GO:0005515=IPI, GO:0005737=ISS, GO:0000287=ISS, GO:0046777=IDA, GO:0001669=IEA, GO:0004674=IDA, GO:0005814=IEA, GO:0007286=ISS, GO:0006468=ISS, GO:0007275=IEA, GO:0005524=ISS, GO:0042802=IPI} multicellular organismal development, protein autophosphorylation, protein phosphorylation, spermatid development acrosomal vesicle, centriole, cytoplasm ATP binding, identical protein binding, magnesium ion binding, protein binding, protein serine/threonine kinase activity Human UniProtKB:Q96PF2 TSSK3 UniProtKB UniProtKB {GO:0000287=GO_REF:0000024, GO:0004674=GO_REF:0000024, GO:0006468=GO_REF:0000024, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000024, GO:0005524=GO_REF:0000024, GO:0030154=GO_REF:0000037} Q96PN8 Testis-specific serine/threonine-protein kinase 3 protein 20060223 {GO:0000287=ISS, GO:0004674=ISS, GO:0006468=ISS, GO:0007275=IEA, GO:0007283=ISS, GO:0005524=ISS, GO:0030154=IEA} cell differentiation, multicellular organismal development, protein phosphorylation, spermatogenesis ATP binding, magnesium ion binding, protein serine/threonine kinase activity Human UniProtKB:Q9BXA7 TSSK4 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0032793=PMID:15964553, GO:0000287=PMID:15964553, GO:0004672=GO_REF:0000002, GO:0004674=PMID:15964553, GO:0006468=PMID:15964553, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0005524=PMID:15964553, GO:0030154=GO_REF:0000037} Q6SA08 Testis-specific serine/threonine-protein kinase 4 protein 20130415 {GO:0005515=IPI, GO:0032793=IDA, GO:0000287=IDA, GO:0004672=IEA, GO:0004674=IDA, GO:0006468=IDA, GO:0007275=IEA, GO:0007283=IEA, GO:0005524=IDA, GO:0030154=IEA} cell differentiation, multicellular organismal development, positive regulation of CREB transcription factor activity, protein phosphorylation, spermatogenesis ATP binding, magnesium ion binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB:P16220 TSSK6 IntAct UniProtKB {GO:0005515=PMID:22939624, GO:0000287=PMID:15870294, GO:0004674=PMID:15870294, GO:0006468=PMID:15870294, GO:0007275=GO_REF:0000037, GO:0005524=PMID:15870294, GO:0035092=GO_REF:0000024} Q9BXA6 Testis-specific serine/threonine-protein kinase 6 protein 20130415 {GO:0005515=IPI, GO:0000287=IDA, GO:0004674=IDA, GO:0006468=IDA, GO:0007275=IEA, GO:0005524=IDA, GO:0035092=ISS} multicellular organismal development, protein phosphorylation, sperm chromatin condensation ATP binding, magnesium ion binding, protein binding, protein serine/threonine kinase activity Human UniProtKB:P08238 TST HPA UniProtKB {GO:0005886=GO_REF:0000052, GO:0005743=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0035928=PMID:20663881, GO:0005739=GO_REF:0000052, GO:0034641=Reactome:REACT_13, GO:0000096=Reactome:REACT_115639, GO:0000098=Reactome:REACT_115654, GO:0005759=Reactome:REACT_115702, GO:0009440=PMID:9070219, GO:0004792=GO_REF:0000003, GO:0008097=PMID:20663881, GO:0051029=PMID:21685364, GO:0070221=Reactome:REACT_116010} Q16762 Thiosulfate sulfurtransferase protein 20080205 {GO:0005886=IDA, GO:0005743=IEA, GO:0044281=TAS, GO:0035928=IMP, GO:0005739=IDA, GO:0034641=TAS, GO:0000096=TAS, GO:0000098=TAS, GO:0005759=TAS, GO:0009440=TAS, GO:0004792=IEA, GO:0008097=IDA, GO:0051029=IDA, GO:0070221=TAS} cellular nitrogen compound metabolic process, cyanate catabolic process, rRNA import into mitochondrion, rRNA transport, small molecule metabolic process, sulfide oxidation, using sulfide:quinone oxidoreductase, sulfur amino acid catabolic process, sulfur amino acid metabolic process mitochondrial inner membrane, mitochondrial matrix, mitochondrion, plasma membrane 5S rRNA binding, thiosulfate sulfurtransferase activity Human TSTA3 UniProtKB UniProtKB {GO:0050662=GO_REF:0000002, GO:0005737=PMID:11698403, GO:0042356=PMID:11698403, GO:0019835=GO_REF:0000019, GO:0007159=PMID:11698403, GO:0019673=PMID:9525924, GO:0009055=PMID:8910301, GO:0042351=PMID:9525924, GO:0016853=GO_REF:0000037, GO:0003824=GO_REF:0000002, GO:0044237=GO_REF:0000002, GO:0050577=PMID:9525924} Q13630 GDP-L-fucose synthase protein 20110815 {GO:0050662=IEA, GO:0005737=IC, GO:0042356=TAS, GO:0019835=IEA, GO:0007159=NAS, GO:0019673=IDA, GO:0009055=TAS, GO:0042351=IDA, GO:0016853=IEA, GO:0003824=IEA, GO:0044237=IEA, GO:0050577=IDA} 'de novo' GDP-L-fucose biosynthetic process, GDP-mannose metabolic process, cellular metabolic process, cytolysis, leukocyte cell-cell adhesion cytoplasm GDP-4-dehydro-D-rhamnose reductase activity, GDP-L-fucose synthase activity, catalytic activity, coenzyme binding, electron carrier activity, isomerase activity Human TSTD2 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q5T7W7 Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2 protein 20091130 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human TTBK1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0030054=GO_REF:0000052, GO:0004674=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037} Q5TCY1 Tau-tubulin kinase 1 protein 20101115 {GO:0005737=IDA, GO:0030054=IDA, GO:0004674=IEA, GO:0005634=IDA, GO:0005524=IEA} cell junction, cytoplasm, nucleus ATP binding, protein serine/threonine kinase activity Human TTBK2 IntAct UniProtKB {GO:0005515=PMID:22863007, GO:0042384=GO_REF:0000024, GO:0008219=GO_REF:0000037, GO:0018105=PMID:21548880, GO:0005814=GO_REF:0000039, GO:0004674=PMID:21548880, GO:0035869=GO_REF:0000024, GO:0005634=PMID:21548880, GO:0005524=GO_REF:0000037, GO:0036064=GO_REF:0000024, GO:0007224=GO_REF:0000024, GO:0005829=PMID:21548880} Q6IQ55 Tau-tubulin kinase 2 protein 20130415 {GO:0005515=IPI, GO:0042384=ISS, GO:0008219=IEA, GO:0018105=IDA, GO:0005814=IEA, GO:0004674=IDA, GO:0035869=ISS, GO:0005634=IDA, GO:0005524=IEA, GO:0036064=ISS, GO:0007224=ISS, GO:0005829=IDA} cell death, cilium assembly, peptidyl-serine phosphorylation, smoothened signaling pathway centriole, ciliary transition zone, cilium basal body, cytosol, nucleus ATP binding, protein binding, protein serine/threonine kinase activity Human UniProtKB:Q9UPV0 TTC1 HGNC UniProtKB {GO:0005515=PMID:14985359, GO:0006457=PMID:8836031, GO:0051082=PMID:8836031, GO:0005778=PMID:21525035} Q99614 Tetratricopeptide repeat protein 1 protein 20070412 {GO:0005515=IPI, GO:0006457=NAS, GO:0051082=NAS, GO:0005778=IDA} protein folding peroxisomal membrane protein binding, unfolded protein binding Human UniProtKB:O14576 TTC12 null null {} null null null null {} null null null TTC13 null null {} null null null null {} null null null TTC14 InterPro UniProtKB {GO:0003723=GO_REF:0000002} Q96N46 Tetratricopeptide repeat protein 14 protein 20130413 {GO:0003723=IEA} RNA binding Human InterPro:IPR003029 TTC17 null null {} null null null null {} null null null TTC19 UniProtKB UniProtKB {GO:0005515=PMID:20208530, GO:0000910=PMID:20208530, GO:0034551=PMID:21278747, GO:0005813=PMID:20208530, GO:0007049=GO_REF:0000037, GO:0005743=PMID:21278747, GO:0030496=PMID:20208530} Q6DKK2 Tetratricopeptide repeat protein 19, mitochondrial protein 20110317 {GO:0005515=IPI, GO:0000910=TAS, GO:0034551=IMP, GO:0005813=TAS, GO:0007049=IEA, GO:0005743=IDA, GO:0030496=TAS} cell cycle, cytokinesis, mitochondrial respiratory chain complex III assembly centrosome, midbody, mitochondrial inner membrane protein binding Human TTC21B UniProtKB UniProtKB {GO:0042073=GO_REF:0000019, GO:0060271=GO_REF:0000019, GO:0030991=PMID:20889716, GO:0035085=GO_REF:0000039, GO:0005856=GO_REF:0000037, GO:0007224=GO_REF:0000019} Q7Z4L5 Tetratricopeptide repeat protein 21B protein 20130222 {GO:0042073=IEA, GO:0060271=IEA, GO:0030991=IDA, GO:0035085=IEA, GO:0005856=IEA, GO:0007224=IEA} cilium morphogenesis, intraflagellar transport, smoothened signaling pathway cilium axoneme, cytoskeleton, intraflagellar transport particle A Human TTC23 null null {} null null null null {} null null null TTC25 LIFEdb UniProtKB {GO:0005737=GO_REF:0000054} Q96NG3 Tetratricopeptide repeat protein 25 protein 20100607 {GO:0005737=IDA} cytoplasm Human TTC26 UniProtKB UniProtKB {GO:0042384=GO_REF:0000024, GO:0072372=GO_REF:0000024} A0AVF1 Tetratricopeptide repeat protein 26 protein 20120730 {GO:0042384=ISS, GO:0072372=ISS} cilium assembly primary cilium Human UniProtKB:Q8BS45 TTC27 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q6P3X3 Tetratricopeptide repeat protein 27 protein 20080829 {GO:0008150=ND, GO:0003674=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human TTC28 UniProtKB UniProtKB {GO:0000922=GO_REF:0000039, GO:0007067=GO_REF:0000037, GO:0005737=GO_REF:0000037, GO:0005815=GO_REF:0000039, GO:0030496=GO_REF:0000039, GO:0051301=GO_REF:0000037} Q96AY4 Tetratricopeptide repeat protein 28 protein 20130413 {GO:0000922=IEA, GO:0007067=IEA, GO:0005737=IEA, GO:0005815=IEA, GO:0030496=IEA, GO:0051301=IEA} cell division, mitosis cytoplasm, microtubule organizing center, midbody, spindle pole Human UniProtKB-SubCell:SL-0469 TTC3 HPA UniProtKB {GO:0005515=PMID:20059950, GO:0005773=GO_REF:0000019, GO:0005739=GO_REF:0000052, GO:0006511=PMID:20059950, GO:0004842=PMID:20059950, GO:0045665=GO_REF:0000019, GO:0010771=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0070936=PMID:20059950} P53804 E3 ubiquitin-protein ligase TTC3 protein 20110516 {GO:0005515=IPI, GO:0005773=IEA, GO:0005739=IDA, GO:0006511=IDA, GO:0004842=IDA, GO:0045665=IEA, GO:0010771=IEA, GO:0005730=IDA, GO:0008270=IEA, GO:0005634=IDA, GO:0070936=IDA} negative regulation of cell morphogenesis involved in differentiation, negative regulation of neuron differentiation, protein K48-linked ubiquitination, ubiquitin-dependent protein catabolic process mitochondrion, nucleolus, nucleus, vacuole protein binding, ubiquitin-protein ligase activity, zinc ion binding Human TTC30A UniProtKB UniProtKB {GO:0005929=GO_REF:0000039, GO:0030030=GO_REF:0000037} Q86WT1 Tetratricopeptide repeat protein 30A protein 20130413 {GO:0005929=IEA, GO:0030030=IEA} cell projection organization cilium Human UniProtKB-SubCell:SL-0066 TTC32 InterPro UniProtKB {GO:0042802=GO_REF:0000002} Q5I0X7 Tetratricopeptide repeat protein 32 protein 20130413 {GO:0042802=IEA} identical protein binding Human InterPro:IPR011717 TTC33 null null {} null null null null {} null null null TTC34 null null {} null null null null {} null null null TTC36 null null {} null null null null {} null null null TTC37 IntAct UniProtKB {GO:0005515=PMID:16024656, GO:0005737=PMID:16024656, GO:0035327=PMID:16024656, GO:0005634=PMID:16024656, GO:0055087=PMID:16024656} Q6PGP7 Tetratricopeptide repeat protein 37 protein 20130415 {GO:0005515=IPI, GO:0005737=IDA, GO:0035327=IDA, GO:0005634=IDA, GO:0055087=IDA} Ski complex, cytoplasm, nucleus, transcriptionally active chromatin protein binding Human UniProtKB:Q8N7H5 TTC38 null null {} null null null null {} null null null TTC39B null null {} null null null null {} null null null TTC39C null null {} null null null null {} null null null TTC4 null null {} null null null null {} null null null TTC5 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0006281=GO_REF:0000037, GO:0045944=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000019} Q8N0Z6 Tetratricopeptide repeat protein 5 protein 20130413 {GO:0005737=IEA, GO:0006281=IEA, GO:0045944=IEA, GO:0003682=IEA, GO:0005634=IEA, GO:0003677=IEA} DNA repair, positive regulation of transcription from RNA polymerase II promoter cytoplasm, nucleus DNA binding, chromatin binding Human UniProtKB-SubCell:SL-0086 TTC7A ENSEMBL UniProtKB {GO:0030097=GO_REF:0000019, GO:0006879=GO_REF:0000019} Q9ULT0 Tetratricopeptide repeat protein 7A protein 20130413 {GO:0030097=IEA, GO:0006879=IEA} cellular iron ion homeostasis, hemopoiesis Human Ensembl:ENSMUSP00000040771 TTC7B null null {} null null null null {} null null null TTC8 BHF-UCL UniProtKB {GO:0005515=PMID:14520415, GO:0005929=PMID:14520415, GO:0042384=PMID:14520415, GO:0005813=PMID:14520415, GO:0060170=GO_REF:0000039, GO:0005737=GO_REF:0000039, GO:0034464=PMID:17574030, GO:0050893=PMID:14520415, GO:0045444=GO_REF:0000019, GO:0032391=GO_REF:0000019, GO:0005932=PMID:14520415, GO:0048560=PMID:14520415} Q8TAM2 Tetratricopeptide repeat protein 8 protein 20080604 {GO:0005515=IPI, GO:0005929=IDA, GO:0042384=TAS, GO:0005813=IDA, GO:0060170=IEA, GO:0005737=IEA, GO:0034464=IDA, GO:0050893=TAS, GO:0045444=IEA, GO:0032391=IEA, GO:0005932=IDA, GO:0048560=IMP} cilium assembly, establishment of anatomical structure orientation, fat cell differentiation, sensory processing BBSome, centrosome, cilium, cilium membrane, cytoplasm, microtubule basal body, photoreceptor connecting cilium protein binding Human TTC9C null null {} null null null null {} null null null TTF1 Reactome UniProtKB {GO:0006353=PMID:7597036, GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000037, GO:0006363=Reactome:REACT_1074, GO:0005730=GO_REF:0000039, GO:0006361=GO_REF:0000019, GO:0005634=PMID:7597036, GO:0006360=Reactome:REACT_1309, GO:0003677=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0006338=GO_REF:0000019, GO:0005654=Reactome:REACT_2228, GO:0008156=GO_REF:0000037} Q15361 Transcription termination factor 1 protein 20130213 {GO:0006353=NAS, GO:0010467=TAS, GO:0006355=IEA, GO:0006363=TAS, GO:0005730=IEA, GO:0006361=IEA, GO:0005634=NAS, GO:0006360=TAS, GO:0003677=IEA, GO:0003682=IEA, GO:0006338=IEA, GO:0005654=TAS, GO:0008156=IEA} DNA-dependent transcription, termination, chromatin remodeling, gene expression, negative regulation of DNA replication, regulation of transcription, DNA-dependent, termination of RNA polymerase I transcription, transcription from RNA polymerase I promoter, transcription initiation from RNA polymerase I promoter nucleolus, nucleoplasm, nucleus DNA binding, chromatin binding Human TTF2 HPA UniProtKB {GO:0008026=GO_REF:0000002, GO:0006397=GO_REF:0000037, GO:0008380=GO_REF:0000037, GO:0005515=PMID:17577209, GO:0006353=PMID:9748214, GO:0006369=PMID:9748214, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0008023=PMID:9748214, GO:0005737=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0005681=GO_REF:0000037, GO:0008094=PMID:9748214} Q9UNY4 Transcription termination factor 2 protein 20101115 {GO:0008026=IEA, GO:0006397=IEA, GO:0008380=IEA, GO:0005515=IPI, GO:0006353=TAS, GO:0006369=TAS, GO:0006355=IEA, GO:0005634=IDA, GO:0003677=IEA, GO:0005524=IEA, GO:0008023=TAS, GO:0005737=IDA, GO:0008270=IEA, GO:0005681=IEA, GO:0008094=TAS} DNA-dependent transcription, termination, RNA splicing, mRNA processing, regulation of transcription, DNA-dependent, termination of RNA polymerase II transcription cytoplasm, nucleus, spliceosomal complex, transcription elongation factor complex ATP binding, ATP-dependent helicase activity, DNA binding, DNA-dependent ATPase activity, protein binding, zinc ion binding Human TTI1 IntAct UniProtKB {GO:0005515=PMID:20810650, GO:0032006=PMID:23263282, GO:0005737=PMID:23263282, GO:0031931=PMID:23263282, GO:0031932=PMID:23263282} O43156 TELO2-interacting protein 1 homolog protein 20130415 {GO:0005515=IPI, GO:0032006=IMP, GO:0005737=IDA, GO:0031931=IDA, GO:0031932=IDA} regulation of TOR signaling cascade TORC1 complex, TORC2 complex, cytoplasm protein binding Human UniProtKB:Q9Y4R8 TTI2 null null {} null null null null {} null null null TTK BHF-UCL UniProtKB {GO:0005515=PMID:19273613, GO:0007094=PMID:10366450, GO:0008284=PMID:1639825, GO:0005819=PMID:10366450, GO:0010862=PMID:19018011, GO:0005524=GO_REF:0000037, GO:0042802=PMID:20360068, GO:0004672=GO_REF:0000002, GO:0004674=GO_REF:0000037, GO:0004712=GO_REF:0000003, GO:0004713=GO_REF:0000037, GO:0007051=PMID:10366450, GO:0007052=PMID:7737118} P33981 Dual specificity protein kinase TTK protein 20090205 {GO:0005515=IPI, GO:0007094=TAS, GO:0008284=TAS, GO:0005819=TAS, GO:0010862=TAS, GO:0005524=IEA, GO:0042802=IPI, GO:0004672=IEA, GO:0004674=IEA, GO:0004712=IEA, GO:0004713=IEA, GO:0007051=TAS, GO:0007052=TAS} mitotic spindle assembly checkpoint, mitotic spindle organization, positive regulation of cell proliferation, positive regulation of pathway-restricted SMAD protein phosphorylation, spindle organization spindle ATP binding, identical protein binding, protein binding, protein kinase activity, protein serine/threonine kinase activity, protein serine/threonine/tyrosine kinase activity, protein tyrosine kinase activity Human TTL ENSEMBL UniProtKB {GO:0030516=GO_REF:0000019, GO:0004835=GO_REF:0000003, GO:0000226=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0006464=GO_REF:0000002} Q8NG68 Tubulin--tyrosine ligase protein 20130413 {GO:0030516=IEA, GO:0004835=IEA, GO:0000226=IEA, GO:0005524=IEA, GO:0006464=IEA} cellular protein modification process, microtubule cytoskeleton organization, regulation of axon extension ATP binding, tubulin-tyrosine ligase activity Human Ensembl:ENSMUSP00000046883 TTLL10 HPA UniProtKB {GO:0018094=PMID:19524510, GO:0031965=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0004835=GO_REF:0000002, GO:0070735=PMID:19524510} Q6ZVT0 Inactive polyglycylase TTLL10 protein 20111111 {GO:0018094=IDA, GO:0031965=IDA, GO:0005737=IDA, GO:0005886=IDA, GO:0004835=IEA, GO:0070735=IDA} protein polyglycylation cytoplasm, nuclear membrane, plasma membrane protein-glycine ligase activity, tubulin-tyrosine ligase activity Human TTLL11 UniProtKB UniProtKB {GO:0005929=GO_REF:0000037, GO:0051013=GO_REF:0000019, GO:0018095=GO_REF:0000019, GO:0005737=GO_REF:0000037, GO:0004835=GO_REF:0000002, GO:0005932=GO_REF:0000039, GO:0006464=GO_REF:0000002} Q8NHH1 Tubulin polyglutamylase TTLL11 protein 20130413 {GO:0005929=IEA, GO:0051013=IEA, GO:0018095=IEA, GO:0005737=IEA, GO:0004835=IEA, GO:0005932=IEA, GO:0006464=IEA} cellular protein modification process, microtubule severing, protein polyglutamylation cilium, cytoplasm, microtubule basal body tubulin-tyrosine ligase activity Human UniProtKB-SubCell:SL-0087 TTLL12 InterPro UniProtKB {GO:0004835=GO_REF:0000002, GO:0006464=GO_REF:0000002} Q14166 Tubulin--tyrosine ligase-like protein 12 protein 20130413 {GO:0004835=IEA, GO:0006464=IEA} cellular protein modification process tubulin-tyrosine ligase activity Human InterPro:IPR004344 TTLL3 UniProtKB UniProtKB {GO:0018094=PMID:19524510, GO:0005929=GO_REF:0000024, GO:0042384=GO_REF:0000024, GO:0035082=GO_REF:0000024, GO:0004835=GO_REF:0000002, GO:0015630=GO_REF:0000024, GO:0005874=GO_REF:0000037, GO:0070735=PMID:19524510, GO:0035085=GO_REF:0000024, GO:0070736=GO_REF:0000024, GO:0006464=GO_REF:0000002} Q9Y4R7 Tubulin monoglycylase TTLL3 protein 20090625 {GO:0018094=IDA, GO:0005929=ISS, GO:0042384=ISS, GO:0035082=ISS, GO:0004835=IEA, GO:0015630=ISS, GO:0005874=IEA, GO:0070735=IDA, GO:0035085=ISS, GO:0070736=ISS, GO:0006464=IEA} axoneme assembly, cellular protein modification process, cilium assembly, protein polyglycylation cilium, cilium axoneme, microtubule, microtubule cytoskeleton protein-glycine ligase activity, protein-glycine ligase activity, initiating, tubulin-tyrosine ligase activity Human UniProtKB:A4Q9E5 TTLL4 UniProtKB UniProtKB {GO:0005929=GO_REF:0000039, GO:0018095=PMID:21074048, GO:0005737=GO_REF:0000037, GO:0004835=GO_REF:0000002, GO:0015631=PMID:21074048, GO:0005932=GO_REF:0000039, GO:0006464=GO_REF:0000002} Q14679 Tubulin polyglutamylase TTLL4 protein 20101123 {GO:0005929=IEA, GO:0018095=ISS, GO:0005737=IEA, GO:0004835=IEA, GO:0015631=ISS, GO:0005932=IEA, GO:0006464=IEA} cellular protein modification process, protein polyglutamylation cilium, cytoplasm, microtubule basal body tubulin binding, tubulin-tyrosine ligase activity Human UniProtKB:Q80UG8 TTLL5 UniProtKB UniProtKB {GO:0005929=GO_REF:0000039, GO:0005813=PMID:21399614, GO:0005737=GO_REF:0000039, GO:0004835=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0005932=GO_REF:0000039, GO:0006351=GO_REF:0000037, GO:0006464=GO_REF:0000002} Q6EMB2 Tubulin polyglutamylase TTLL5 protein 20110517 {GO:0005929=IEA, GO:0005813=IDA, GO:0005737=IEA, GO:0004835=IEA, GO:0005634=IEA, GO:0005932=IEA, GO:0006351=IEA, GO:0006464=IEA} cellular protein modification process, transcription, DNA-dependent centrosome, cilium, cytoplasm, microtubule basal body, nucleus tubulin-tyrosine ligase activity Human TTLL6 UniProtKB UniProtKB {GO:0005515=PMID:22246503, GO:0051013=GO_REF:0000019, GO:0018095=GO_REF:0000024, GO:0005737=GO_REF:0000037, GO:0004835=GO_REF:0000002, GO:0015631=GO_REF:0000024, GO:0001578=GO_REF:0000019, GO:0036064=PMID:22246503, GO:0006464=GO_REF:0000002} Q8N841 Tubulin polyglutamylase TTLL6 protein 20120127 {GO:0005515=IPI, GO:0051013=IEA, GO:0018095=ISS, GO:0005737=IEA, GO:0004835=IEA, GO:0015631=ISS, GO:0001578=IEA, GO:0036064=IDA, GO:0006464=IEA} cellular protein modification process, microtubule bundle formation, microtubule severing, protein polyglutamylation cilium basal body, cytoplasm protein binding, tubulin binding, tubulin-tyrosine ligase activity Human UniProtKB:A8CVX7 TTLL7 UniProtKB UniProtKB {GO:0005929=GO_REF:0000039, GO:0005737=GO_REF:0000037, GO:0004835=GO_REF:0000002, GO:0043204=GO_REF:0000039, GO:0005932=GO_REF:0000039, GO:0030425=GO_REF:0000039, GO:0030154=GO_REF:0000037, GO:0006464=GO_REF:0000002, GO:0007399=GO_REF:0000037} Q6ZT98 Tubulin polyglutamylase TTLL7 protein 20130413 {GO:0005929=IEA, GO:0005737=IEA, GO:0004835=IEA, GO:0043204=IEA, GO:0005932=IEA, GO:0030425=IEA, GO:0030154=IEA, GO:0006464=IEA, GO:0007399=IEA} cell differentiation, cellular protein modification process, nervous system development cilium, cytoplasm, dendrite, microtubule basal body, perikaryon tubulin-tyrosine ligase activity Human UniProtKB-SubCell:SL-0197 TTN HPA UniProtKB {GO:0005515=PMID:14583192, GO:0045859=PMID:9804419, GO:0005516=PMID:7607248, GO:0007076=PMID:9548712, GO:0030018=PMID:9817758, GO:0006941=PMID:7569978, GO:0042805=PMID:11846417, GO:0002020=PMID:9642272, GO:0043621=PMID:9804419, GO:0060048=PMID:11846417, GO:0007512=GO_REF:0000019, GO:0042802=PMID:9804419, GO:0006936=PMID:10481174, GO:0051015=PMID:9501083, GO:0055003=PMID:11846417, GO:0008307=PMID:9817758, GO:0055008=PMID:9817758, GO:0005794=GO_REF:0000052, GO:0005509=PMID:7607248, GO:0045214=PMID:11846417, GO:0031433=PMID:15582318, GO:0030168=Reactome:REACT_798, GO:0035995=PMID:12507422, GO:0001701=GO_REF:0000019, GO:0031430=GO_REF:0000019, GO:0051592=PMID:7607248, GO:0048739=PMID:9817758, GO:0019899=PMID:18310072, GO:0031674=PMID:9817758, GO:0030240=PMID:9817758, GO:0005634=GO_REF:0000052, GO:0005829=Reactome:REACT_21347, GO:0003300=PMID:11846417, GO:0005737=GO_REF:0000052, GO:0048769=PMID:9817758, GO:0000794=PMID:9548712, GO:0030049=Reactome:REACT_16969, GO:0005730=GO_REF:0000052, GO:0005576=Reactome:REACT_21347, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0051371=PMID:9501083, GO:0003007=GO_REF:0000019, GO:0050790=PMID:9804419, GO:0007596=Reactome:REACT_604, GO:0004674=PMID:9804419, GO:0002576=Reactome:REACT_318, GO:0004713=GO_REF:0000002, GO:0043056=GO_REF:0000019, GO:0030241=PMID:9817758} Q8WZ42 Titin protein 20120912 {GO:0005515=IPI, GO:0045859=IMP, GO:0005516=IPI, GO:0007076=IEP, GO:0030018=IDA, GO:0006941=TAS, GO:0042805=IPI, GO:0002020=IPI, GO:0043621=IDA, GO:0060048=IMP, GO:0007512=IEA, GO:0042802=IPI, GO:0006936=NAS, GO:0051015=IDA, GO:0055003=IMP, GO:0008307=IMP, GO:0055008=IMP, GO:0005794=IDA, GO:0005509=IDA, GO:0045214=IMP, GO:0031433=IPI, GO:0030168=TAS, GO:0035995=TAS, GO:0001701=IEA, GO:0031430=IEA, GO:0051592=IDA, GO:0048739=IMP, GO:0019899=IPI, GO:0031674=IDA, GO:0030240=IMP, GO:0005634=IDA, GO:0005829=TAS, GO:0003300=IMP, GO:0005737=IDA, GO:0048769=IMP, GO:0000794=IDA, GO:0030049=TAS, GO:0005730=IDA, GO:0005576=TAS, GO:0003676=IEA, GO:0005524=IEA, GO:0051371=IPI, GO:0003007=IEA, GO:0050790=IMP, GO:0007596=TAS, GO:0004674=IDA, GO:0002576=TAS, GO:0004713=IEA, GO:0043056=IEA, GO:0030241=IMP} adult heart development, blood coagulation, cardiac muscle contraction, cardiac muscle fiber development, cardiac muscle hypertrophy, cardiac muscle tissue morphogenesis, cardiac myofibril assembly, detection of muscle stretch, forward locomotion, heart morphogenesis, in utero embryonic development, mitotic chromosome condensation, muscle contraction, muscle filament sliding, platelet activation, platelet degranulation, regulation of catalytic activity, regulation of protein kinase activity, response to calcium ion, sarcomere organization, sarcomerogenesis, skeletal muscle myosin thick filament assembly, skeletal muscle thin filament assembly, striated muscle contraction Golgi apparatus, I band, M band, Z disc, condensed nuclear chromosome, cytoplasm, cytosol, extracellular region, nucleolus, nucleus ATP binding, actin filament binding, actinin binding, calcium ion binding, calmodulin binding, enzyme binding, identical protein binding, muscle alpha-actinin binding, nucleic acid binding, protease binding, protein binding, protein self-association, protein serine/threonine kinase activity, protein tyrosine kinase activity, structural constituent of muscle, telethonin binding Human TTPA PINC UniProtKB {GO:0006629=PMID:7887897, GO:0005215=GO_REF:0000002, GO:0090212=GO_REF:0000019, GO:0007584=GO_REF:0000019, GO:0005770=GO_REF:0000019, GO:0006810=PMID:7887897, GO:0009636=GO_REF:0000019, GO:0001892=GO_REF:0000019, GO:0008431=GO_REF:0000019, GO:0042360=GO_REF:0000019, GO:0009268=GO_REF:0000019, GO:0005829=GO_REF:0000019} P49638 Alpha-tocopherol transfer protein protein 20030904 {GO:0006629=TAS, GO:0005215=IEA, GO:0090212=IEA, GO:0007584=IEA, GO:0005770=IEA, GO:0006810=TAS, GO:0009636=IEA, GO:0001892=IEA, GO:0008431=IEA, GO:0042360=IEA, GO:0009268=IEA, GO:0005829=IEA} embryonic placenta development, lipid metabolic process, negative regulation of establishment of blood-brain barrier, response to nutrient, response to pH, response to toxic substance, transport, vitamin E metabolic process cytosol, late endosome transporter activity, vitamin E binding Human TTPAL InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0005215=GO_REF:0000002} Q9BTX7 Alpha-tocopherol transfer protein-like protein 20130413 {GO:0005622=IEA, GO:0005215=IEA} intracellular transporter activity Human InterPro:IPR001071 TTR Reactome UniProtKB {GO:0005515=PMID:986177, GO:0043234=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0007603=Reactome:REACT_160125, GO:0046982=GO_REF:0000019, GO:0005179=GO_REF:0000037, GO:0042572=GO_REF:0000019, GO:0042562=GO_REF:0000019, GO:0006810=GO_REF:0000037, GO:0005576=Reactome:REACT_160313, GO:0001523=Reactome:REACT_160156, GO:0005615=GO_REF:0000019} P02766 Transthyretin protein 20120917 {GO:0005515=IPI, GO:0043234=IEA, GO:0005737=IEA, GO:0007603=TAS, GO:0046982=IEA, GO:0005179=IEA, GO:0042572=IEA, GO:0042562=IEA, GO:0006810=IEA, GO:0005576=TAS, GO:0001523=TAS, GO:0005615=IEA} phototransduction, visible light, retinoid metabolic process, retinol metabolic process, transport cytoplasm, extracellular region, extracellular space, protein complex hormone activity, hormone binding, protein binding, protein heterodimerization activity Human TTYH1 GOC UniProtKB {GO:0005886=Reactome:REACT_160181, GO:0005509=GO_REF:0000019, GO:0031589=GO_REF:0000019, GO:0034707=GO_REF:0000037, GO:0031527=GO_REF:0000019, GO:0055085=Reactome:REACT_15518, GO:0005254=GO_REF:0000037, GO:0032433=GO_REF:0000019, GO:0007067=GO_REF:0000019, GO:0016337=GO_REF:0000019, GO:0034220=Reactome:REACT_25300, GO:0030868=GO_REF:0000019, GO:0005381=PMID:10950931, GO:0006826=PMID:10950931, GO:0046847=GO_REF:0000019, GO:0016021=PMID:10950931, GO:0034755=PMID:10950931} Q9H313 Protein tweety homolog 1 protein 20130413 {GO:0005886=TAS, GO:0005509=IEA, GO:0031589=IEA, GO:0034707=IEA, GO:0031527=IEA, GO:0055085=TAS, GO:0005254=IEA, GO:0032433=IEA, GO:0007067=IEA, GO:0016337=IEA, GO:0034220=TAS, GO:0030868=IEA, GO:0005381=NAS, GO:0006826=NAS, GO:0046847=IEA, GO:0016021=TAS, GO:0034755=NAS} cell-cell adhesion, cell-substrate adhesion, filopodium assembly, ion transmembrane transport, iron ion transmembrane transport, iron ion transport, mitosis, transmembrane transport chloride channel complex, filopodium membrane, filopodium tip, integral to membrane, plasma membrane, smooth endoplasmic reticulum membrane calcium ion binding, chloride channel activity, iron ion transmembrane transporter activity Human TTYH2 UniProtKB UniProtKB {GO:0005515=PMID:18577513, GO:0005886=GO_REF:0000039, GO:0034707=GO_REF:0000037, GO:0005254=GO_REF:0000037} Q9BSA4 Protein tweety homolog 2 protein 20081006 {GO:0005515=IPI, GO:0005886=IEA, GO:0034707=IEA, GO:0005254=IEA} chloride channel complex, plasma membrane chloride channel activity, protein binding Human UniProtKB:Q96PU5 TTYH3 Reactome UniProtKB {GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_160263, GO:0034707=GO_REF:0000037, GO:0055085=Reactome:REACT_15518, GO:0005254=PMID:15010458} Q9C0H2 Protein tweety homolog 3 protein 20130301 {GO:0034220=TAS, GO:0005886=TAS, GO:0034707=IEA, GO:0055085=TAS, GO:0005254=IMP} ion transmembrane transport, transmembrane transport chloride channel complex, plasma membrane chloride channel activity Human TUB HPA UniProtKB {GO:0006909=GO_REF:0000037, GO:0060041=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0007605=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0008020=GO_REF:0000019, GO:0043231=GO_REF:0000052, GO:0005829=GO_REF:0000019, GO:0005737=PMID:11000483, GO:0050766=PMID:19837063, GO:0044259=GO_REF:0000019, GO:0009725=GO_REF:0000019, GO:0007602=GO_REF:0000019} P50607 Tubby protein homolog protein 20100326 {GO:0006909=IEA, GO:0060041=IEA, GO:0005886=IEA, GO:0007605=IEA, GO:0005576=IEA, GO:0005634=IEA, GO:0008020=IEA, GO:0043231=IDA, GO:0005829=IEA, GO:0005737=TAS, GO:0050766=IDA, GO:0044259=IEA, GO:0009725=IEA, GO:0007602=IEA} multicellular organismal macromolecule metabolic process, phagocytosis, phototransduction, positive regulation of phagocytosis, response to hormone stimulus, retina development in camera-type eye, sensory perception of sound cytoplasm, cytosol, extracellular region, intracellular membrane-bounded organelle, nucleus, plasma membrane G-protein coupled photoreceptor activity Human TUBA1A HPA UniProtKB {GO:0005881=GO_REF:0000019, GO:0051258=GO_REF:0000002, GO:0005874=PMID:12090300, GO:0003924=GO_REF:0000002, GO:0000226=GO_REF:0000019, GO:0005525=GO_REF:0000037, GO:0005829=Reactome:REACT_15470, GO:0030705=PMID:12090300, GO:0005198=PMID:12090300, GO:0006457=Reactome:REACT_17004, GO:0000086=Reactome:REACT_2203, GO:0015630=GO_REF:0000052, GO:0005200=GO_REF:0000002, GO:0051084=Reactome:REACT_16952, GO:0007017=PMID:12090300, GO:0000278=Reactome:REACT_152, GO:0044267=Reactome:REACT_17015, GO:0051301=PMID:12090300} Q71U36 Tubulin alpha-1A chain protein 20111111 {GO:0005881=IEA, GO:0051258=IEA, GO:0005874=TAS, GO:0003924=IEA, GO:0000226=IEA, GO:0005525=IEA, GO:0005829=TAS, GO:0030705=TAS, GO:0005198=TAS, GO:0006457=TAS, GO:0000086=TAS, GO:0015630=IDA, GO:0005200=IEA, GO:0051084=TAS, GO:0007017=TAS, GO:0000278=TAS, GO:0044267=TAS, GO:0051301=TAS} 'de novo' posttranslational protein folding, G2/M transition of mitotic cell cycle, cell division, cellular protein metabolic process, cytoskeleton-dependent intracellular transport, microtubule cytoskeleton organization, microtubule-based process, mitotic cell cycle, protein folding, protein polymerization cytoplasmic microtubule, cytosol, microtubule, microtubule cytoskeleton GTP binding, GTPase activity, structural constituent of cytoskeleton, structural molecule activity Human TUBA1B HPA UniProtKB {GO:0005515=PMID:11698390, GO:0005881=GO_REF:0000019, GO:0051258=GO_REF:0000002, GO:0005874=PMID:12090300, GO:0003924=GO_REF:0000002, GO:0000226=GO_REF:0000019, GO:0005525=GO_REF:0000037, GO:0030705=PMID:12090300, GO:0005198=PMID:12090300, GO:0006457=Reactome:REACT_17004, GO:0015630=GO_REF:0000052, GO:0005200=GO_REF:0000019, GO:0051084=Reactome:REACT_16952, GO:0007017=PMID:12090300, GO:0044267=Reactome:REACT_17015, GO:0051301=PMID:12090300} P68363 Tubulin alpha-1B chain protein 20111111 {GO:0005515=IPI, GO:0005881=IEA, GO:0051258=IEA, GO:0005874=TAS, GO:0003924=IEA, GO:0000226=IEA, GO:0005525=IEA, GO:0030705=TAS, GO:0005198=TAS, GO:0006457=TAS, GO:0015630=IDA, GO:0005200=IEA, GO:0051084=TAS, GO:0007017=TAS, GO:0044267=TAS, GO:0051301=TAS} 'de novo' posttranslational protein folding, cell division, cellular protein metabolic process, cytoskeleton-dependent intracellular transport, microtubule cytoskeleton organization, microtubule-based process, protein folding, protein polymerization cytoplasmic microtubule, microtubule, microtubule cytoskeleton GTP binding, GTPase activity, protein binding, structural constituent of cytoskeleton, structural molecule activity Human TUBA1C HPA UniProtKB {GO:0005881=GO_REF:0000019, GO:0051258=GO_REF:0000002, GO:0005874=PMID:12090300, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0030705=PMID:12090300, GO:0005737=GO_REF:0000038, GO:0006457=Reactome:REACT_17004, GO:0005198=PMID:12090300, GO:0015630=GO_REF:0000052, GO:0005200=GO_REF:0000002, GO:0051084=Reactome:REACT_16952, GO:0007017=PMID:12090300, GO:0044267=Reactome:REACT_17015, GO:0051301=PMID:12090300} Q9BQE3 Tubulin alpha-1C chain protein 20111111 {GO:0005881=IEA, GO:0051258=IEA, GO:0005874=TAS, GO:0003924=IEA, GO:0005525=IEA, GO:0030705=TAS, GO:0005737=IEA, GO:0006457=TAS, GO:0005198=TAS, GO:0015630=IDA, GO:0005200=IEA, GO:0051084=TAS, GO:0007017=TAS, GO:0044267=TAS, GO:0051301=TAS} 'de novo' posttranslational protein folding, cell division, cellular protein metabolic process, cytoskeleton-dependent intracellular transport, microtubule-based process, protein folding, protein polymerization cytoplasm, cytoplasmic microtubule, microtubule, microtubule cytoskeleton GTP binding, GTPase activity, structural constituent of cytoskeleton, structural molecule activity Human TUBA3C HPA UniProtKB {GO:0005515=PMID:16189514, GO:0005737=GO_REF:0000037, GO:0051258=GO_REF:0000002, GO:0006457=Reactome:REACT_17004, GO:0015630=GO_REF:0000052, GO:0005874=GO_REF:0000029, GO:0005200=GO_REF:0000002, GO:0003924=GO_REF:0000002, GO:0051084=Reactome:REACT_16952, GO:0005525=GO_REF:0000029, GO:0007017=GO_REF:0000029, GO:0044267=Reactome:REACT_17015} Q13748 Tubulin alpha-3C/D chain protein 20111111 {GO:0005515=IPI, GO:0005737=IEA, GO:0051258=IEA, GO:0006457=TAS, GO:0015630=IDA, GO:0005874=NAS, GO:0005200=IEA, GO:0003924=IEA, GO:0051084=TAS, GO:0005525=NAS, GO:0007017=NAS, GO:0044267=TAS} 'de novo' posttranslational protein folding, cellular protein metabolic process, microtubule-based process, protein folding, protein polymerization cytoplasm, microtubule, microtubule cytoskeleton GTP binding, GTPase activity, protein binding, structural constituent of cytoskeleton Human TUBA3D null null {} null null null null {} null null null TUBA3E HPA UniProtKB {GO:0005737=GO_REF:0000037, GO:0051258=GO_REF:0000002, GO:0015630=GO_REF:0000052, GO:0005874=GO_REF:0000037, GO:0005200=GO_REF:0000002, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0007017=GO_REF:0000002} Q6PEY2 Tubulin alpha-3E chain protein 20111111 {GO:0005737=IEA, GO:0051258=IEA, GO:0015630=IDA, GO:0005874=IEA, GO:0005200=IEA, GO:0003924=IEA, GO:0005525=IEA, GO:0007017=IEA} microtubule-based process, protein polymerization cytoplasm, microtubule, microtubule cytoskeleton GTP binding, GTPase activity, structural constituent of cytoskeleton Human TUBA4A HPA UniProtKB {GO:0005881=GO_REF:0000019, GO:0051258=GO_REF:0000002, GO:0005874=PMID:21525035, GO:0003924=GO_REF:0000002, GO:0030168=Reactome:REACT_798, GO:0000226=GO_REF:0000019, GO:0005576=Reactome:REACT_21347, GO:0005525=GO_REF:0000037, GO:0005829=Reactome:REACT_21347, GO:0005737=GO_REF:0000038, GO:0007596=Reactome:REACT_604, GO:0006457=Reactome:REACT_17004, GO:0000086=Reactome:REACT_2203, GO:0015630=GO_REF:0000052, GO:0002576=Reactome:REACT_318, GO:0005200=GO_REF:0000002, GO:0051084=Reactome:REACT_16952, GO:0007017=GO_REF:0000002, GO:0000278=Reactome:REACT_152, GO:0044267=Reactome:REACT_17015} P68366 Tubulin alpha-4A chain protein 20111111 {GO:0005881=IEA, GO:0051258=IEA, GO:0005874=IDA, GO:0003924=IEA, GO:0030168=TAS, GO:0000226=IEA, GO:0005576=TAS, GO:0005525=IEA, GO:0005829=TAS, GO:0005737=IEA, GO:0007596=TAS, GO:0006457=TAS, GO:0000086=TAS, GO:0015630=IDA, GO:0002576=TAS, GO:0005200=IEA, GO:0051084=TAS, GO:0007017=IEA, GO:0000278=TAS, GO:0044267=TAS} 'de novo' posttranslational protein folding, G2/M transition of mitotic cell cycle, blood coagulation, cellular protein metabolic process, microtubule cytoskeleton organization, microtubule-based process, mitotic cell cycle, platelet activation, platelet degranulation, protein folding, protein polymerization cytoplasm, cytoplasmic microtubule, cytosol, extracellular region, microtubule, microtubule cytoskeleton GTP binding, GTPase activity, structural constituent of cytoskeleton Human TUBA8 UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0051258=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0005200=GO_REF:0000002, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0007017=GO_REF:0000002} Q9NY65 Tubulin alpha-8 chain protein 20130413 {GO:0005737=IEA, GO:0051258=IEA, GO:0005874=IEA, GO:0005200=IEA, GO:0003924=IEA, GO:0005525=IEA, GO:0007017=IEA} microtubule-based process, protein polymerization cytoplasm, microtubule GTP binding, GTPase activity, structural constituent of cytoskeleton Human UniProtKB-KW:KW-0493 TUBAL3 UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0051258=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0005200=GO_REF:0000002, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0007017=GO_REF:0000002} A6NHL2 Tubulin alpha chain-like 3 protein 20130413 {GO:0005737=IEA, GO:0051258=IEA, GO:0005874=IEA, GO:0005200=IEA, GO:0003924=IEA, GO:0005525=IEA, GO:0007017=IEA} microtubule-based process, protein polymerization cytoplasm, microtubule GTP binding, GTPase activity, structural constituent of cytoskeleton Human UniProtKB-KW:KW-0493 TUBB HPA UniProtKB {GO:0051258=GO_REF:0000002, GO:0042288=PMID:11120798, GO:0005886=GO_REF:0000052, GO:0042267=PMID:11120798, GO:0003924=GO_REF:0000002, GO:0006928=PMID:16130169, GO:0005634=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0005829=Reactome:REACT_15470, GO:0005737=GO_REF:0000052, GO:0000086=Reactome:REACT_2203, GO:0005641=PMID:19567321, GO:0015630=GO_REF:0000052, GO:0007017=GO_REF:0000002, GO:0005856=PMID:16130169, GO:0009987=PMID:19567321, GO:0005874=GO_REF:0000019, GO:0005525=GO_REF:0000038, GO:0051225=GO_REF:0000019, GO:0044297=PMID:19567321, GO:0030705=PMID:12090300, GO:0005198=PMID:12090300, GO:0005200=GO_REF:0000019, GO:0000278=Reactome:REACT_152, GO:0051301=PMID:12090300} Q5ST81 Tubulin beta chain protein 20120912 {GO:0051258=IEA, GO:0042288=IDA, GO:0005886=IDA, GO:0042267=NAS, GO:0003924=IEA, GO:0006928=TAS, GO:0005634=IEA, GO:0032403=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0000086=TAS, GO:0005641=IDA, GO:0015630=IDA, GO:0007017=IEA, GO:0005856=TAS, GO:0009987=IDA, GO:0005874=IEA, GO:0005525=IEA, GO:0051225=IEA, GO:0044297=IDA, GO:0030705=TAS, GO:0005198=TAS, GO:0005200=IEA, GO:0000278=TAS, GO:0051301=TAS} G2/M transition of mitotic cell cycle, cell division, cellular component movement, cellular process, cytoskeleton-dependent intracellular transport, microtubule-based process, mitotic cell cycle, natural killer cell mediated cytotoxicity, protein polymerization, spindle assembly cell body, cytoplasm, cytoskeleton, cytosol, microtubule, microtubule cytoskeleton, nuclear envelope lumen, nucleus, plasma membrane GTP binding, GTPase activity, MHC class I protein binding, protein complex binding, structural constituent of cytoskeleton, structural molecule activity Human TUBB1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0051258=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0006457=Reactome:REACT_17004, GO:0015630=GO_REF:0000052, GO:0005874=GO_REF:0000019, GO:0005200=GO_REF:0000019, GO:0003924=GO_REF:0000002, GO:0051084=Reactome:REACT_16952, GO:0005525=GO_REF:0000037, GO:0044267=Reactome:REACT_17015, GO:0051225=GO_REF:0000019} Q9H4B7 Tubulin beta-1 chain protein 20120912 {GO:0005737=IDA, GO:0051258=IEA, GO:0005886=IDA, GO:0006457=TAS, GO:0015630=IDA, GO:0005874=IEA, GO:0005200=IEA, GO:0003924=IEA, GO:0051084=TAS, GO:0005525=IEA, GO:0044267=TAS, GO:0051225=IEA} 'de novo' posttranslational protein folding, cellular protein metabolic process, protein folding, protein polymerization, spindle assembly cytoplasm, microtubule, microtubule cytoskeleton, plasma membrane GTP binding, GTPase activity, structural constituent of cytoskeleton Human TUBB2A HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0051258=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0006457=Reactome:REACT_17004, GO:0015630=GO_REF:0000052, GO:0005874=PMID:21525035, GO:0005200=GO_REF:0000002, GO:0003924=GO_REF:0000002, GO:0051084=Reactome:REACT_16952, GO:0005525=GO_REF:0000037, GO:0007017=GO_REF:0000002, GO:0044267=Reactome:REACT_17015} Q13885 Tubulin beta-2A chain protein 20120912 {GO:0005737=IDA, GO:0051258=IEA, GO:0005886=IDA, GO:0006457=TAS, GO:0015630=IDA, GO:0005874=IDA, GO:0005200=IEA, GO:0003924=IEA, GO:0051084=TAS, GO:0005525=IEA, GO:0007017=IEA, GO:0044267=TAS} 'de novo' posttranslational protein folding, cellular protein metabolic process, microtubule-based process, protein folding, protein polymerization cytoplasm, microtubule, microtubule cytoskeleton, plasma membrane GTP binding, GTPase activity, structural constituent of cytoskeleton Human TUBB2B HPA UniProtKB {GO:0005515=PMID:21078624, GO:0051258=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0005874=PMID:21525035, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0006457=Reactome:REACT_17004, GO:0015630=GO_REF:0000052, GO:0005200=GO_REF:0000002, GO:0051084=Reactome:REACT_16952, GO:0007017=GO_REF:0000002, GO:0001764=PMID:19465910, GO:0044267=Reactome:REACT_17015} Q9BVA1 Tubulin beta-2B chain protein 20120912 {GO:0005515=IPI, GO:0051258=IEA, GO:0005886=IDA, GO:0005874=IDA, GO:0003924=IEA, GO:0005525=IEA, GO:0005737=IDA, GO:0006457=TAS, GO:0015630=IDA, GO:0005200=IEA, GO:0051084=TAS, GO:0007017=IEA, GO:0001764=IMP, GO:0044267=TAS} 'de novo' posttranslational protein folding, cellular protein metabolic process, microtubule-based process, neuron migration, protein folding, protein polymerization cytoplasm, microtubule, microtubule cytoskeleton, plasma membrane GTP binding, GTPase activity, protein binding, structural constituent of cytoskeleton Human TUBB3 HPA UniProtKB {GO:0030424=GO_REF:0000019, GO:0042277=GO_REF:0000019, GO:0051258=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0005874=PMID:21525035, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0007067=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0006457=Reactome:REACT_17004, GO:0007411=PMID:20074521, GO:0015630=GO_REF:0000052, GO:0005200=GO_REF:0000002, GO:0051084=Reactome:REACT_16952, GO:0007017=GO_REF:0000002, GO:0044267=Reactome:REACT_17015} Q13509 Tubulin beta-3 chain protein 20120912 {GO:0030424=IEA, GO:0042277=IEA, GO:0051258=IEA, GO:0005886=IDA, GO:0005874=IDA, GO:0003924=IEA, GO:0005525=IEA, GO:0007067=IEA, GO:0005737=IDA, GO:0006457=TAS, GO:0007411=IMP, GO:0015630=IDA, GO:0005200=IEA, GO:0051084=TAS, GO:0007017=IEA, GO:0044267=TAS} 'de novo' posttranslational protein folding, axon guidance, cellular protein metabolic process, microtubule-based process, mitosis, protein folding, protein polymerization axon, cytoplasm, microtubule, microtubule cytoskeleton, plasma membrane GTP binding, GTPase activity, peptide binding, structural constituent of cytoskeleton Human TUBB4A HPA UniProtKB {GO:0005515=PMID:20195357, GO:0051258=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0005874=PMID:21525035, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0005829=Reactome:REACT_15470, GO:0051297=GO_REF:0000002, GO:0005929=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0033269=GO_REF:0000019, GO:0006457=Reactome:REACT_17004, GO:0043209=GO_REF:0000019, GO:0000086=Reactome:REACT_2203, GO:0015630=GO_REF:0000052, GO:0005200=GO_REF:0000002, GO:0043025=GO_REF:0000019, GO:0051084=Reactome:REACT_16952, GO:0000278=Reactome:REACT_152, GO:0007017=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0000242=GO_REF:0000002} P04350 Tubulin beta-4A chain protein 20120912 {GO:0005515=IPI, GO:0051258=IEA, GO:0005886=IDA, GO:0005874=IDA, GO:0003924=IEA, GO:0005525=IEA, GO:0005829=TAS, GO:0051297=IEA, GO:0005929=IEA, GO:0005737=IDA, GO:0033269=IEA, GO:0006457=TAS, GO:0043209=IEA, GO:0000086=TAS, GO:0015630=IDA, GO:0005200=IEA, GO:0043025=IEA, GO:0051084=TAS, GO:0000278=TAS, GO:0007017=IEA, GO:0044267=TAS, GO:0000242=IEA} 'de novo' posttranslational protein folding, G2/M transition of mitotic cell cycle, cellular protein metabolic process, centrosome organization, microtubule-based process, mitotic cell cycle, protein folding, protein polymerization cilium, cytoplasm, cytosol, internode region of axon, microtubule, microtubule cytoskeleton, myelin sheath, neuronal cell body, pericentriolar material, plasma membrane GTP binding, GTPase activity, protein binding, structural constituent of cytoskeleton Human TUBB4B HPA UniProtKB {GO:0051258=GO_REF:0000002, GO:0042288=PMID:11120798, GO:0005886=GO_REF:0000052, GO:0042267=PMID:11120798, GO:0005874=PMID:21525035, GO:0003924=GO_REF:0000002, GO:0006928=PMID:16130169, GO:0005525=GO_REF:0000037, GO:0005829=Reactome:REACT_15470, GO:0005737=GO_REF:0000052, GO:0006457=Reactome:REACT_17004, GO:0000086=Reactome:REACT_2203, GO:0015630=GO_REF:0000052, GO:0005200=GO_REF:0000002, GO:0051084=Reactome:REACT_16952, GO:0051082=PMID:11120798, GO:0007017=GO_REF:0000002, GO:0005856=PMID:16130169, GO:0000278=Reactome:REACT_152, GO:0044267=Reactome:REACT_17015} P68371 Tubulin beta-4B chain protein 20120912 {GO:0051258=IEA, GO:0042288=TAS, GO:0005886=IDA, GO:0042267=NAS, GO:0005874=IDA, GO:0003924=IEA, GO:0006928=TAS, GO:0005525=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0006457=TAS, GO:0000086=TAS, GO:0015630=IDA, GO:0005200=IEA, GO:0051084=TAS, GO:0051082=NAS, GO:0007017=IEA, GO:0005856=TAS, GO:0000278=TAS, GO:0044267=TAS} 'de novo' posttranslational protein folding, G2/M transition of mitotic cell cycle, cellular component movement, cellular protein metabolic process, microtubule-based process, mitotic cell cycle, natural killer cell mediated cytotoxicity, protein folding, protein polymerization cytoplasm, cytoskeleton, cytosol, microtubule, microtubule cytoskeleton, plasma membrane GTP binding, GTPase activity, MHC class I protein binding, structural constituent of cytoskeleton, unfolded protein binding Human TUBB6 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0051258=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0006457=Reactome:REACT_17004, GO:0015630=GO_REF:0000052, GO:0005874=PMID:21525035, GO:0003924=GO_REF:0000002, GO:0005200=GO_REF:0000002, GO:0051084=Reactome:REACT_16952, GO:0005525=GO_REF:0000037, GO:0007017=GO_REF:0000002, GO:0044267=Reactome:REACT_17015} Q9BUF5 Tubulin beta-6 chain protein 20120912 {GO:0005737=IDA, GO:0051258=IEA, GO:0005886=IDA, GO:0006457=TAS, GO:0015630=IDA, GO:0005874=IDA, GO:0003924=IEA, GO:0005200=IEA, GO:0051084=TAS, GO:0005525=IEA, GO:0007017=IEA, GO:0044267=TAS} 'de novo' posttranslational protein folding, cellular protein metabolic process, microtubule-based process, protein folding, protein polymerization cytoplasm, microtubule, microtubule cytoskeleton, plasma membrane GTP binding, GTPase activity, structural constituent of cytoskeleton Human TUBB8 HPA UniProtKB {GO:0043234=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0051258=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0015630=GO_REF:0000052, GO:0005874=PMID:21525035, GO:0005200=GO_REF:0000002, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000038, GO:0007017=GO_REF:0000002} Q5SQY0 Tubulin beta-8 chain protein 20120912 {GO:0043234=IEA, GO:0005737=IDA, GO:0051258=IEA, GO:0005886=IDA, GO:0015630=IDA, GO:0005874=IDA, GO:0005200=IEA, GO:0003924=IEA, GO:0005525=IEA, GO:0007017=IEA} microtubule-based process, protein polymerization cytoplasm, microtubule, microtubule cytoskeleton, plasma membrane, protein complex GTP binding, GTPase activity, structural constituent of cytoskeleton Human TUBD1 HPA UniProtKB {GO:0051258=GO_REF:0000002, GO:0005794=GO_REF:0000052, GO:0005814=GO_REF:0000039, GO:0005874=GO_REF:0000037, GO:0003924=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0007275=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0005525=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0051297=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0005200=GO_REF:0000002, GO:0007017=GO_REF:0000002, GO:0000242=GO_REF:0000002} Q9UJT1 Tubulin delta chain protein 20101115 {GO:0051258=IEA, GO:0005794=IDA, GO:0005814=IEA, GO:0005874=IEA, GO:0003924=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0007275=IEA, GO:0007283=IEA, GO:0005525=IEA, GO:0030154=IEA, GO:0051297=IEA, GO:0005737=IDA, GO:0005200=IEA, GO:0007017=IEA, GO:0000242=IEA} cell differentiation, centrosome organization, microtubule-based process, multicellular organismal development, protein polymerization, spermatogenesis Golgi apparatus, centriole, cytoplasm, microtubule, nucleolus, nucleus, pericentriolar material GTP binding, GTPase activity, structural constituent of cytoskeleton Human TUBE1 PINC UniProtKB {GO:0051297=GO_REF:0000002, GO:0051258=GO_REF:0000002, GO:0007098=PMID:10620804, GO:0005874=GO_REF:0000037, GO:0005200=PMID:10620804, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0000242=GO_REF:0000002} Q9UJT0 Tubulin epsilon chain protein 20030904 {GO:0051297=IEA, GO:0051258=IEA, GO:0007098=TAS, GO:0005874=IEA, GO:0005200=TAS, GO:0003924=IEA, GO:0005525=IEA, GO:0000242=IEA} centrosome cycle, centrosome organization, protein polymerization microtubule, pericentriolar material GTP binding, GTPase activity, structural constituent of cytoskeleton Human TUBG1 IntAct UniProtKB {GO:0005515=PMID:20360068, GO:0005827=PMID:9566969, GO:0051258=GO_REF:0000002, GO:0000794=GO_REF:0000024, GO:0005813=PMID:21399614, GO:0005874=GO_REF:0000038, GO:0003924=GO_REF:0000002, GO:0000226=PMID:1904010, GO:0005525=GO_REF:0000037, GO:0000212=GO_REF:0000024, GO:0005829=Reactome:REACT_15470, GO:0005737=PMID:9566969, GO:0000086=Reactome:REACT_2203, GO:0000930=PMID:9566969, GO:0005200=PMID:1904010, GO:0000278=Reactome:REACT_152, GO:0007017=GO_REF:0000002} P23258 Tubulin gamma-1 chain protein 20130415 {GO:0005515=IPI, GO:0005827=IDA, GO:0051258=IEA, GO:0000794=ISS, GO:0005813=IDA, GO:0005874=IEA, GO:0003924=IEA, GO:0000226=TAS, GO:0005525=IEA, GO:0000212=ISS, GO:0005829=TAS, GO:0005737=IDA, GO:0000086=TAS, GO:0000930=TAS, GO:0005200=TAS, GO:0000278=TAS, GO:0007017=IEA} G2/M transition of mitotic cell cycle, meiotic spindle organization, microtubule cytoskeleton organization, microtubule-based process, mitotic cell cycle, protein polymerization centrosome, condensed nuclear chromosome, cytoplasm, cytosol, gamma-tubulin complex, microtubule, polar microtubule GTP binding, GTPase activity, protein binding, structural constituent of cytoskeleton Human UniProtKB:Q6NZ67 TUBG2 Reactome UniProtKB {GO:0005881=GO_REF:0000019, GO:0051258=GO_REF:0000002, GO:0005874=PMID:21525035, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0005829=Reactome:REACT_15467, GO:0005198=PMID:10903841, GO:0000086=Reactome:REACT_2203, GO:0015630=PMID:10903841, GO:0005876=GO_REF:0000019, GO:0007017=GO_REF:0000002, GO:0000278=Reactome:REACT_152, GO:0000242=GO_REF:0000019} Q9NRH3 Tubulin gamma-2 chain protein 20130213 {GO:0005881=IEA, GO:0051258=IEA, GO:0005874=IDA, GO:0003924=IEA, GO:0005525=IEA, GO:0005829=TAS, GO:0005198=TAS, GO:0000086=TAS, GO:0015630=TAS, GO:0005876=IEA, GO:0007017=IEA, GO:0000278=TAS, GO:0000242=IEA} G2/M transition of mitotic cell cycle, microtubule-based process, mitotic cell cycle, protein polymerization cytoplasmic microtubule, cytosol, microtubule, microtubule cytoskeleton, pericentriolar material, spindle microtubule GTP binding, GTPase activity, structural molecule activity Human TUBGCP2 HPA UniProtKB {GO:0005515=PMID:16980960, GO:0005881=PMID:9566967, GO:0005813=GO_REF:0000052, GO:0005815=PMID:9566967, GO:0005730=GO_REF:0000052, GO:0000226=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0005829=Reactome:REACT_15467, GO:0000922=GO_REF:0000002, GO:0006461=PMID:9566967, GO:0007020=PMID:9566967, GO:0000086=Reactome:REACT_2203, GO:0000278=Reactome:REACT_152} Q9BSJ2 Gamma-tubulin complex component 2 protein 20120912 {GO:0005515=IPI, GO:0005881=TAS, GO:0005813=IDA, GO:0005815=TAS, GO:0005730=IDA, GO:0000226=IEA, GO:0005634=IDA, GO:0005829=TAS, GO:0000922=IEA, GO:0006461=TAS, GO:0007020=TAS, GO:0000086=TAS, GO:0000278=TAS} G2/M transition of mitotic cell cycle, microtubule cytoskeleton organization, microtubule nucleation, mitotic cell cycle, protein complex assembly centrosome, cytoplasmic microtubule, cytosol, microtubule organizing center, nucleolus, nucleus, spindle pole protein binding Human TUBGCP3 Reactome UniProtKB {GO:0005515=PMID:17959831, GO:0005827=PMID:9566969, GO:0005813=PMID:21399614, GO:0043015=PMID:9566969, GO:0005814=PMID:9566969, GO:0005819=PMID:7876350, GO:0005829=Reactome:REACT_15467, GO:0007338=PMID:9138452, GO:0005737=PMID:9566969, GO:0005198=PMID:9566967, GO:0007020=PMID:9566969, GO:0000086=Reactome:REACT_2203, GO:0005200=PMID:9566969, GO:0000278=Reactome:REACT_152} Q96CW5 Gamma-tubulin complex component 3 protein 20130213 {GO:0005515=IPI, GO:0005827=IDA, GO:0005813=IDA, GO:0043015=IDA, GO:0005814=IDA, GO:0005819=NAS, GO:0005829=TAS, GO:0007338=NAS, GO:0005737=IDA, GO:0005198=NAS, GO:0007020=NAS, GO:0000086=TAS, GO:0005200=NAS, GO:0000278=TAS} G2/M transition of mitotic cell cycle, microtubule nucleation, mitotic cell cycle, single fertilization centriole, centrosome, cytoplasm, cytosol, polar microtubule, spindle gamma-tubulin binding, protein binding, structural constituent of cytoskeleton, structural molecule activity Human TUBGCP4 HPA UniProtKB {GO:0005813=GO_REF:0000052, GO:0005815=GO_REF:0000002, GO:0005874=GO_REF:0000037, GO:0000226=GO_REF:0000002, GO:0005829=Reactome:REACT_15467, GO:0000922=GO_REF:0000002, GO:0006461=PMID:10562286, GO:0007020=PMID:10562286, GO:0000086=Reactome:REACT_2203, GO:0015630=PMID:10562286, GO:0005200=PMID:10562286, GO:0000278=Reactome:REACT_152, GO:0008274=PMID:10562286} Q9UGJ1 Gamma-tubulin complex component 4 protein 20110516 {GO:0005813=IDA, GO:0005815=IEA, GO:0005874=IEA, GO:0000226=IEA, GO:0005829=TAS, GO:0000922=IEA, GO:0006461=NAS, GO:0007020=NAS, GO:0000086=TAS, GO:0015630=TAS, GO:0005200=NAS, GO:0000278=TAS, GO:0008274=NAS} G2/M transition of mitotic cell cycle, microtubule cytoskeleton organization, microtubule nucleation, mitotic cell cycle, protein complex assembly centrosome, cytosol, gamma-tubulin ring complex, microtubule, microtubule cytoskeleton, microtubule organizing center, spindle pole structural constituent of cytoskeleton Human TUBGCP5 Reactome UniProtKB {GO:0008017=PMID:11694571, GO:0005813=PMID:21399614, GO:0000922=GO_REF:0000002, GO:0005815=GO_REF:0000002, GO:0000086=Reactome:REACT_2203, GO:0007020=PMID:11694571, GO:0005874=GO_REF:0000037, GO:0000226=GO_REF:0000002, GO:0000278=Reactome:REACT_152, GO:0008274=PMID:11694571, GO:0005829=Reactome:REACT_15467} Q96RT8 Gamma-tubulin complex component 5 protein 20130213 {GO:0008017=IDA, GO:0005813=IDA, GO:0000922=IEA, GO:0005815=IEA, GO:0000086=TAS, GO:0007020=IDA, GO:0005874=IEA, GO:0000226=IEA, GO:0000278=TAS, GO:0008274=IDA, GO:0005829=TAS} G2/M transition of mitotic cell cycle, microtubule cytoskeleton organization, microtubule nucleation, mitotic cell cycle centrosome, cytosol, gamma-tubulin ring complex, microtubule, microtubule organizing center, spindle pole microtubule binding Human TUBGCP6 Reactome UniProtKB {GO:0008017=PMID:11694571, GO:0005813=PMID:21399614, GO:0000922=GO_REF:0000002, GO:0005815=GO_REF:0000002, GO:0000086=Reactome:REACT_2203, GO:0007020=PMID:11694571, GO:0005874=GO_REF:0000037, GO:0000226=GO_REF:0000002, GO:0000278=Reactome:REACT_152, GO:0008274=PMID:11694571, GO:0005829=Reactome:REACT_15467} Q96RT7 Gamma-tubulin complex component 6 protein 20130213 {GO:0008017=IDA, GO:0005813=IDA, GO:0000922=IEA, GO:0005815=IEA, GO:0000086=TAS, GO:0007020=IDA, GO:0005874=IEA, GO:0000226=IEA, GO:0000278=TAS, GO:0008274=IDA, GO:0005829=TAS} G2/M transition of mitotic cell cycle, microtubule cytoskeleton organization, microtubule nucleation, mitotic cell cycle centrosome, cytosol, gamma-tubulin ring complex, microtubule, microtubule organizing center, spindle pole microtubule binding Human TUFM HPA UniProtKB {GO:0042645=PMID:18063578, GO:0005739=GO_REF:0000052, GO:0005622=GO_REF:0000002, GO:0003924=GO_REF:0000002, GO:0005525=GO_REF:0000037, GO:0003746=PMID:9332382, GO:0006414=PMID:9332382} P49411 Elongation factor Tu, mitochondrial protein 20100326 {GO:0042645=IDA, GO:0005739=IDA, GO:0005622=IEA, GO:0003924=IEA, GO:0005525=IEA, GO:0003746=IDA, GO:0006414=IDA} translational elongation intracellular, mitochondrial nucleoid, mitochondrion GTP binding, GTPase activity, translation elongation factor activity Human TUFT1 LIFEdb UniProtKB {GO:0005737=GO_REF:0000054, GO:0030345=PMID:12489194, GO:0042476=PMID:12489194, GO:0005576=PMID:12489194, GO:0030282=PMID:12489194} Q9NNX1 Tuftelin protein 20100607 {GO:0005737=IDA, GO:0030345=NAS, GO:0042476=NAS, GO:0005576=NAS, GO:0030282=NAS} bone mineralization, odontogenesis cytoplasm, extracellular region structural constituent of tooth enamel Human TULP1 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0006909=GO_REF:0000037, GO:0030054=GO_REF:0000037, GO:0005886=PMID:16303976, GO:0060041=GO_REF:0000019, GO:0045202=GO_REF:0000024, GO:0005546=PMID:16303976, GO:0005576=GO_REF:0000039, GO:0042995=PMID:16303976, GO:0045494=GO_REF:0000024, GO:0016358=GO_REF:0000024, GO:0008020=GO_REF:0000019, GO:0001917=GO_REF:0000024, GO:0005737=GO_REF:0000039, GO:0050766=PMID:19837063, GO:0051015=PMID:16303976, GO:0007602=GO_REF:0000019, GO:0007601=PMID:9462750, GO:0042462=GO_REF:0000024, GO:0001750=GO_REF:0000024} O00294 Tubby-related protein 1 protein 20130415 {GO:0005515=IPI, GO:0006909=IEA, GO:0030054=IEA, GO:0005886=IDA, GO:0060041=IEA, GO:0045202=ISS, GO:0005546=IDA, GO:0005576=IEA, GO:0042995=IDA, GO:0045494=ISS, GO:0016358=ISS, GO:0008020=IEA, GO:0001917=ISS, GO:0005737=IEA, GO:0050766=IDA, GO:0051015=IDA, GO:0007602=IEA, GO:0007601=TAS, GO:0042462=ISS, GO:0001750=ISS} dendrite development, eye photoreceptor cell development, phagocytosis, photoreceptor cell maintenance, phototransduction, positive regulation of phagocytosis, retina development in camera-type eye, visual perception cell junction, cell projection, cytoplasm, extracellular region, photoreceptor inner segment, photoreceptor outer segment, plasma membrane, synapse G-protein coupled photoreceptor activity, actin filament binding, phosphatidylinositol-4,5-bisphosphate binding, protein binding Human UniProtKB:P16333 TULP2 PINC UniProtKB {GO:0005737=GO_REF:0000039, GO:0005576=GO_REF:0000039, GO:0007601=PMID:9096357} O00295 Tubby-related protein 2 protein 20030904 {GO:0005737=IEA, GO:0005576=IEA, GO:0007601=TAS} visual perception cytoplasm, extracellular region Human TULP3 IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0005886=PMID:11375483, GO:0005634=PMID:20889716, GO:0045879=PMID:20889716, GO:0060831=GO_REF:0000019, GO:0048702=GO_REF:0000019, GO:0035085=GO_REF:0000019, GO:0031076=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0060434=GO_REF:0000019, GO:0006355=PMID:11375483, GO:0021953=GO_REF:0000019, GO:0001843=GO_REF:0000019, GO:0005546=PMID:11375483, GO:0005576=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0072372=PMID:20889716, GO:0001701=GO_REF:0000019, GO:0008277=PMID:20889716, GO:0007186=PMID:11375483, GO:0007420=GO_REF:0000019, GO:0030991=PMID:20889716, GO:0035091=PMID:20889716, GO:0042733=GO_REF:0000019, GO:0021914=GO_REF:0000019} O75386 Tubby-related protein 3 protein 20130415 {GO:0005515=IPI, GO:0005886=NAS, GO:0005634=IDA, GO:0045879=IDA, GO:0060831=IEA, GO:0048702=IEA, GO:0035085=IEA, GO:0031076=IEA, GO:0005737=IEA, GO:0060434=IEA, GO:0006355=NAS, GO:0021953=IEA, GO:0001843=IEA, GO:0005546=NAS, GO:0005576=IEA, GO:0007275=IEA, GO:0072372=IDA, GO:0001701=IEA, GO:0008277=IDA, GO:0007186=NAS, GO:0007420=IEA, GO:0030991=IDA, GO:0035091=IDA, GO:0042733=IEA, GO:0021914=IEA} G-protein coupled receptor signaling pathway, brain development, bronchus morphogenesis, central nervous system neuron differentiation, embryonic camera-type eye development, embryonic digit morphogenesis, embryonic neurocranium morphogenesis, in utero embryonic development, multicellular organismal development, negative regulation of smoothened signaling pathway, negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning, neural tube closure, regulation of G-protein coupled receptor protein signaling pathway, regulation of transcription, DNA-dependent, smoothened signaling pathway involved in dorsal/ventral neural tube patterning cilium axoneme, cytoplasm, extracellular region, intraflagellar transport particle A, nucleus, plasma membrane, primary cilium phosphatidylinositol binding, phosphatidylinositol-4,5-bisphosphate binding, protein binding Human UniProtKB:P12520 TULP4 MGI UniProtKB {GO:0035556=GO_REF:0000002, GO:0005737=PMID:11595174, GO:0006355=PMID:11595174, GO:0016567=GO_REF:0000041, GO:0003700=PMID:11595174, GO:0007584=PMID:8612280} Q9NRJ4 Tubby-related protein 4 protein 20040716 {GO:0035556=IEA, GO:0005737=IDA, GO:0006355=NAS, GO:0016567=IEA, GO:0003700=NAS, GO:0007584=TAS} intracellular signal transduction, protein ubiquitination, regulation of transcription, DNA-dependent, response to nutrient cytoplasm sequence-specific DNA binding transcription factor activity Human TUSC1 null null {} null null null null {} null null null TUSC2 PINC UniProtKB {GO:0005739=GO_REF:0000019, GO:0032618=GO_REF:0000019, GO:0007049=GO_REF:0000037, GO:0008283=PMID:8780057, GO:0007267=PMID:8780057, GO:0048469=GO_REF:0000019, GO:0001779=GO_REF:0000019} O75896 Tumor suppressor candidate 2 protein 20030904 {GO:0005739=IEA, GO:0032618=IEA, GO:0007049=IEA, GO:0008283=TAS, GO:0007267=TAS, GO:0048469=IEA, GO:0001779=IEA} cell cycle, cell maturation, cell proliferation, cell-cell signaling, interleukin-15 production, natural killer cell differentiation mitochondrion Human TUSC3 Reactome UniProtKB {GO:0015693=PMID:19717468, GO:0015095=PMID:19717468, GO:0005739=GO_REF:0000024, GO:0050890=PMID:18455129, GO:0005887=PMID:19717468, GO:0004579=GO_REF:0000024, GO:0005789=Reactome:REACT_22208, GO:0045454=GO_REF:0000002, GO:0006487=PMID:18455129, GO:0008250=PMID:15835887, GO:0044267=Reactome:REACT_17015, GO:0018279=Reactome:REACT_22426, GO:0043687=Reactome:REACT_22161} Q13454 Tumor suppressor candidate 3 protein 20100301 {GO:0015693=IMP, GO:0015095=IMP, GO:0005739=ISS, GO:0050890=IMP, GO:0005887=NAS, GO:0004579=ISS, GO:0005789=TAS, GO:0045454=IEA, GO:0006487=NAS, GO:0008250=IDA, GO:0044267=TAS, GO:0018279=TAS, GO:0043687=TAS} cell redox homeostasis, cellular protein metabolic process, cognition, magnesium ion transport, post-translational protein modification, protein N-linked glycosylation, protein N-linked glycosylation via asparagine endoplasmic reticulum membrane, integral to plasma membrane, mitochondrion, oligosaccharyltransferase complex dolichyl-diphosphooligosaccharide-protein glycotransferase activity, magnesium ion transmembrane transporter activity Human TUT1 UniProtKB UniProtKB {GO:0005515=PMID:18288197, GO:0006379=PMID:21102410, GO:0006378=PMID:18288197, GO:0003723=PMID:18288197, GO:0005730=PMID:16790842, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0050265=PMID:18288197, GO:0004652=PMID:18288197, GO:0016607=PMID:18288197, GO:0000166=GO_REF:0000002, GO:0071044=PMID:18172165, GO:0005847=PMID:18305108, GO:0003730=PMID:21102410, GO:0019899=PMID:18305108, GO:0016180=PMID:16790842} Q9H6E5 Speckle targeted PIP5K1A-regulated poly(A) polymerase protein 20101217 {GO:0005515=IPI, GO:0006379=IDA, GO:0006378=IMP, GO:0003723=IDA, GO:0005730=IDA, GO:0003676=IEA, GO:0005524=IEA, GO:0046872=IEA, GO:0050265=IDA, GO:0004652=IDA, GO:0016607=IDA, GO:0000166=IEA, GO:0071044=IMP, GO:0005847=IDA, GO:0003730=IDA, GO:0019899=IPI, GO:0016180=IMP} histone mRNA catabolic process, mRNA cleavage, mRNA polyadenylation, snRNA processing mRNA cleavage and polyadenylation specificity factor complex, nuclear speck, nucleolus ATP binding, RNA binding, RNA uridylyltransferase activity, enzyme binding, mRNA 3'-UTR binding, metal ion binding, nucleic acid binding, nucleotide binding, polynucleotide adenylyltransferase activity, protein binding Human UniProtKB:Q9UKF6 TWF1 HPA UniProtKB {GO:0042989=PMID:18837697, GO:0048471=PMID:12807912, GO:0005546=PMID:12807912, GO:0003779=GO_REF:0000002, GO:0032587=PMID:12807912, GO:0030175=PMID:12807912, GO:0030016=PMID:18837697, GO:0015629=GO_REF:0000024, GO:0005524=PMID:10406962, GO:0005622=GO_REF:0000002, GO:0003785=PMID:18837697, GO:0005737=GO_REF:0000052, GO:0051016=GO_REF:0000019, GO:0005911=PMID:12807912, GO:0030837=PMID:12807912, GO:0004713=PMID:10406962, GO:0043538=PMID:10406962} Q12792 Twinfilin-1 protein 20090616 {GO:0042989=ISS, GO:0048471=ISS, GO:0005546=ISS, GO:0003779=IEA, GO:0032587=ISS, GO:0030175=ISS, GO:0030016=ISS, GO:0015629=ISS, GO:0005524=IDA, GO:0005622=IEA, GO:0003785=ISS, GO:0005737=IDA, GO:0051016=IEA, GO:0005911=ISS, GO:0030837=ISS, GO:0004713=IDA, GO:0043538=IDA} barbed-end actin filament capping, negative regulation of actin filament polymerization, regulation of actin phosphorylation, sequestering of actin monomers actin cytoskeleton, cell-cell junction, cytoplasm, filopodium, intracellular, myofibril, perinuclear region of cytoplasm, ruffle membrane ATP binding, actin binding, actin monomer binding, phosphatidylinositol-4,5-bisphosphate binding, protein tyrosine kinase activity Human TWF2 BHF-UCL UniProtKB {GO:0032532=PMID:19955359, GO:0048471=PMID:12807912, GO:0071300=PMID:17910947, GO:0045773=PMID:17910947, GO:0030175=PMID:12807912, GO:0030016=PMID:18837697, GO:0030426=PMID:17910947, GO:0005622=GO_REF:0000002, GO:0010592=PMID:17910947, GO:0005737=PMID:10406962, GO:0051016=PMID:18837697, GO:0032956=PMID:17910947, GO:0030837=PMID:12807912, GO:0005080=PMID:10406962, GO:0005856=GO_REF:0000039, GO:0042989=PMID:18837697, GO:0005546=PMID:12807912, GO:0032420=PMID:19955359, GO:0003779=GO_REF:0000002, GO:0005524=PMID:10406962, GO:0030027=PMID:12807912, GO:0003785=PMID:18837697, GO:0071363=PMID:17910947, GO:0010976=PMID:17910947, GO:0030030=GO_REF:0000037} Q6IBS0 Twinfilin-2 protein 20110707 {GO:0032532=IC, GO:0048471=ISS, GO:0071300=IMP, GO:0045773=IMP, GO:0030175=ISS, GO:0030016=ISS, GO:0030426=IDA, GO:0005622=IEA, GO:0010592=IMP, GO:0005737=NAS, GO:0051016=ISS, GO:0032956=IMP, GO:0030837=ISS, GO:0005080=IPI, GO:0005856=IEA, GO:0042989=ISS, GO:0005546=ISS, GO:0032420=ISS, GO:0003779=IEA, GO:0005524=IDA, GO:0030027=ISS, GO:0003785=ISS, GO:0071363=IMP, GO:0010976=IMP, GO:0030030=IEA} barbed-end actin filament capping, cell projection organization, cellular response to growth factor stimulus, cellular response to retinoic acid, negative regulation of actin filament polymerization, positive regulation of axon extension, positive regulation of lamellipodium assembly, positive regulation of neuron projection development, regulation of actin cytoskeleton organization, regulation of microvillus length, sequestering of actin monomers cytoplasm, cytoskeleton, filopodium, growth cone, intracellular, lamellipodium, myofibril, perinuclear region of cytoplasm, stereocilium ATP binding, actin binding, actin monomer binding, phosphatidylinositol-4,5-bisphosphate binding, protein kinase C binding Human GO:0032420 TWIST1 GOC UniProtKB {GO:0005515=PMID:18598946, GO:0006366=PMID:17332325, GO:0003180=PMID:20804746, GO:0000981=PMID:17332325, GO:0003183=GO_REF:0000019, GO:0048701=PMID:8988167, GO:2000147=PMID:17332325, GO:0042803=GO_REF:0000019, GO:2000793=PMID:20804746, GO:0071639=PMID:20007935, GO:0046983=GO_REF:0000002, GO:0030500=PMID:19597909, GO:0046982=GO_REF:0000019, GO:0032760=PMID:20007935, GO:0019904=GO_REF:0000019, GO:0001843=GO_REF:0000019, GO:0032720=GO_REF:0000019, GO:0070888=PMID:17332325, GO:0000122=PMID:17690110, GO:0014067=PMID:17003487, GO:0048642=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0001649=GO_REF:0000019, GO:0007517=GO_REF:0000037, GO:0001503=PMID:11001584, GO:2000276=GO_REF:0000019, GO:0042733=PMID:11001584, GO:0008134=PMID:15545268, GO:2000780=PMID:17690110, GO:2000679=PMID:12270142, GO:0035359=GO_REF:0000019, GO:0010718=PMID:18297062, GO:0005634=PMID:10749989, GO:0035067=GO_REF:0000019, GO:0043433=GO_REF:0000019, GO:0061029=PMID:17070479, GO:2000778=PMID:20007935, GO:0045944=PMID:17332325, GO:0042473=PMID:11001584, GO:2000773=PMID:17690110, GO:0060900=PMID:17070479, GO:2000802=GO_REF:0000019, GO:0003203=GO_REF:0000019, GO:0071456=PMID:18297062, GO:0043425=PMID:10749989, GO:0006915=GO_REF:0000019, GO:0045766=PMID:17987801, GO:0010628=PMID:17003487, GO:0033128=PMID:17690110, GO:0045668=PMID:16888803, GO:0060363=PMID:11001584, GO:0035116=GO_REF:0000019, GO:0032000=PMID:20007935, GO:0043518=PMID:17690110, GO:0003253=GO_REF:0000019, GO:0035115=GO_REF:0000019, GO:0001764=GO_REF:0000019} Q15672 Twist-related protein 1 protein 20130413 {GO:0005515=IPI, GO:0006366=IDA, GO:0003180=IMP, GO:0000981=IDA, GO:0003183=IEA, GO:0048701=IMP, GO:2000147=IMP, GO:0042803=IEA, GO:2000793=IMP, GO:0071639=IMP, GO:0046983=IEA, GO:0030500=IMP, GO:0046982=IEA, GO:0032760=IMP, GO:0019904=IEA, GO:0001843=IEA, GO:0032720=IEA, GO:0070888=IDA, GO:0000122=IMP, GO:0014067=IMP, GO:0048642=IEA, GO:0001701=IEA, GO:0001649=IEA, GO:0007517=IEA, GO:0001503=TAS, GO:2000276=IEA, GO:0042733=TAS, GO:0008134=IPI, GO:2000780=IMP, GO:2000679=IMP, GO:0035359=IEA, GO:0010718=IMP, GO:0005634=IDA, GO:0035067=IEA, GO:0043433=IEA, GO:0061029=IMP, GO:2000778=IMP, GO:0045944=IDA, GO:0042473=TAS, GO:2000773=IMP, GO:0060900=IMP, GO:2000802=IEA, GO:0003203=IEA, GO:0071456=IMP, GO:0043425=IPI, GO:0006915=IEA, GO:0045766=NAS, GO:0010628=IMP, GO:0033128=IMP, GO:0045668=IMP, GO:0060363=TAS, GO:0035116=IEA, GO:0032000=IMP, GO:0043518=IMP, GO:0003253=IEA, GO:0035115=IEA, GO:0001764=IEA} aortic valve morphogenesis, apoptotic process, cardiac neural crest cell migration involved in outflow tract morphogenesis, cell proliferation involved in heart valve development, cellular response to hypoxia, cranial suture morphogenesis, embryonic camera-type eye formation, embryonic cranial skeleton morphogenesis, embryonic digit morphogenesis, embryonic forelimb morphogenesis, embryonic hindlimb morphogenesis, endocardial cushion morphogenesis, eyelid development in camera-type eye, in utero embryonic development, mitral valve morphogenesis, muscle organ development, negative regulation of DNA damage response, signal transduction by p53 class mediator, negative regulation of cellular senescence, negative regulation of double-strand break repair, negative regulation of histone acetylation, negative regulation of histone phosphorylation, negative regulation of osteoblast differentiation, negative regulation of oxidative phosphorylation uncoupler activity, negative regulation of peroxisome proliferator activated receptor signaling pathway, negative regulation of phosphatidylinositol 3-kinase cascade, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of skeletal muscle tissue development, negative regulation of transcription from RNA polymerase II promoter, negative regulation of tumor necrosis factor production, neural tube closure, neuron migration, ossification, osteoblast differentiation, outer ear morphogenesis, positive regulation of angiogenesis, positive regulation of cell motility, positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation, positive regulation of epithelial to mesenchymal transition, positive regulation of fatty acid beta-oxidation, positive regulation of gene expression, positive regulation of interleukin-6 secretion, positive regulation of monocyte chemotactic protein-1 production, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription regulatory region DNA binding, positive regulation of tumor necrosis factor production, regulation of bone mineralization, transcription from RNA polymerase II promoter nucleus E-box binding, bHLH transcription factor binding, protein binding, protein dimerization activity, protein domain specific binding, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding RNA polymerase II transcription factor activity, transcription factor binding Human TWIST2 IntAct UniProtKB {GO:0005515=PMID:18598946, GO:0005667=GO_REF:0000019, GO:0010838=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0003700=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0032720=GO_REF:0000019, GO:0005634=PMID:11062344, GO:0000122=GO_REF:0000019, GO:0048701=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0001649=GO_REF:0000019, GO:0043392=GO_REF:0000019, GO:0061303=GO_REF:0000019, GO:0005737=PMID:11062344, GO:0045668=PMID:11062344, GO:0001076=GO_REF:0000019, GO:0060325=GO_REF:0000019, GO:0045638=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0046983=GO_REF:0000002, GO:0045892=GO_REF:0000024} Q8WVJ9 Twist-related protein 2 protein 20130415 {GO:0005515=IPI, GO:0005667=IEA, GO:0010838=IEA, GO:0043066=IEA, GO:0003700=IEA, GO:0008285=IEA, GO:0019904=IEA, GO:0032720=IEA, GO:0005634=IDA, GO:0000122=IEA, GO:0048701=IEA, GO:0003677=IEA, GO:0001649=IEA, GO:0043392=IEA, GO:0061303=IEA, GO:0005737=IDA, GO:0045668=IDA, GO:0001076=IEA, GO:0060325=IEA, GO:0045638=IEA, GO:0003682=IEA, GO:0046983=IEA, GO:0045892=ISS} cornea development in camera-type eye, embryonic cranial skeleton morphogenesis, face morphogenesis, negative regulation of DNA binding, negative regulation of apoptotic process, negative regulation of cell proliferation, negative regulation of myeloid cell differentiation, negative regulation of osteoblast differentiation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, negative regulation of tumor necrosis factor production, osteoblast differentiation, positive regulation of keratinocyte proliferation cytoplasm, nucleus, transcription factor complex DNA binding, RNA polymerase II transcription factor binding transcription factor activity, chromatin binding, protein binding, protein dimerization activity, protein domain specific binding, sequence-specific DNA binding transcription factor activity Human UniProtKB:P15036 TWISTNB HPA UniProtKB {GO:0003899=GO_REF:0000037, GO:0015630=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000002} Q3B726 DNA-directed RNA polymerase I subunit RPA43 protein 20100326 {GO:0003899=IEA, GO:0015630=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0006351=IEA} transcription, DNA-dependent microtubule cytoskeleton, nucleolus, nucleus DNA-directed RNA polymerase activity Human TWSG1 ENSEMBL UniProtKB {GO:0030514=GO_REF:0000019, GO:0030097=GO_REF:0000019, GO:0030513=GO_REF:0000019, GO:0045668=GO_REF:0000019, GO:0001707=GO_REF:0000019, GO:0001503=GO_REF:0000019, GO:0043010=GO_REF:0000019, GO:0030900=GO_REF:0000019, GO:0030509=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0030154=GO_REF:0000019, GO:0007435=GO_REF:0000019} Q9GZX9 Twisted gastrulation protein homolog 1 protein 20130413 {GO:0030514=IEA, GO:0030097=IEA, GO:0030513=IEA, GO:0045668=IEA, GO:0001707=IEA, GO:0001503=IEA, GO:0043010=IEA, GO:0030900=IEA, GO:0030509=IEA, GO:0005615=IEA, GO:0030154=IEA, GO:0007435=IEA} BMP signaling pathway, camera-type eye development, cell differentiation, forebrain development, hemopoiesis, mesoderm formation, negative regulation of BMP signaling pathway, negative regulation of osteoblast differentiation, ossification, positive regulation of BMP signaling pathway, salivary gland morphogenesis extracellular space Human Ensembl:ENSMUSP00000024906 TXK PINC UniProtKB {GO:0032729=PMID:10523612, GO:0050852=GO_REF:0000024, GO:0005886=GO_REF:0000039, GO:0006357=PMID:11859127, GO:0005634=PMID:10523612, GO:0007202=GO_REF:0000024, GO:0001816=GO_REF:0000024, GO:0005524=GO_REF:0000037, GO:0001865=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0002250=GO_REF:0000024, GO:0060335=PMID:11859127, GO:0005737=PMID:10523612, GO:0046777=PMID:12081135, GO:0004672=GO_REF:0000002, GO:0006468=PMID:7951233, GO:0004713=GO_REF:0000002, GO:0032633=GO_REF:0000019, GO:0001012=PMID:11859127, GO:0032609=GO_REF:0000019, GO:0004715=GO_REF:0000003} P42681 Tyrosine-protein kinase TXK protein 20030904 {GO:0032729=IDA, GO:0050852=ISS, GO:0005886=IEA, GO:0006357=IDA, GO:0005634=IDA, GO:0007202=ISS, GO:0001816=ISS, GO:0005524=IEA, GO:0001865=IEA, GO:0006351=IEA, GO:0002250=ISS, GO:0060335=IDA, GO:0005737=IDA, GO:0046777=IDA, GO:0004672=IEA, GO:0006468=TAS, GO:0004713=IEA, GO:0032633=IEA, GO:0001012=IDA, GO:0032609=IEA, GO:0004715=IEA} NK T cell differentiation, T cell receptor signaling pathway, activation of phospholipase C activity, adaptive immune response, cytokine production, interferon-gamma production, interleukin-4 production, positive regulation of interferon-gamma production, positive regulation of interferon-gamma-mediated signaling pathway, protein autophosphorylation, protein phosphorylation, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, nucleus, plasma membrane ATP binding, RNA polymerase II regulatory region DNA binding, non-membrane spanning protein tyrosine kinase activity, protein kinase activity, protein tyrosine kinase activity Human TXLNA IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0019905=GO_REF:0000002, GO:0005737=GO_REF:0000054, GO:0008283=PMID:8327514, GO:0030372=PMID:8327514, GO:0005576=PMID:8327514, GO:0006887=GO_REF:0000037, GO:0005125=PMID:8327514} P40222 Alpha-taxilin protein 20130415 {GO:0005515=IPI, GO:0019905=IEA, GO:0005737=IDA, GO:0008283=NAS, GO:0030372=NAS, GO:0005576=NAS, GO:0006887=IEA, GO:0005125=NAS} cell proliferation, exocytosis cytoplasm, extracellular region cytokine activity, high molecular weight B cell growth factor receptor binding, protein binding, syntaxin binding Human UniProtKB:Q9UHD2 TXLNB IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0019905=GO_REF:0000002, GO:0005737=GO_REF:0000054} Q8N3L3 Beta-taxilin protein 20130415 {GO:0005515=IPI, GO:0019905=IEA, GO:0005737=IDA} cytoplasm protein binding, syntaxin binding Human UniProtKB:P40222 TXLNG UniProtKB UniProtKB {GO:0019905=GO_REF:0000002, GO:0030500=GO_REF:0000024, GO:0031965=PMID:15911876, GO:0007049=GO_REF:0000037, GO:0006355=GO_REF:0000037, GO:0046982=PMID:15911876, GO:0051726=GO_REF:0000024, GO:0010564=PMID:18068885, GO:0006351=GO_REF:0000037, GO:0005829=GO_REF:0000024} Q9NUQ3 Gamma-taxilin protein 20111206 {GO:0019905=IEA, GO:0030500=ISS, GO:0031965=IDA, GO:0007049=IEA, GO:0006355=IEA, GO:0046982=IDA, GO:0051726=ISS, GO:0010564=IMP, GO:0006351=IEA, GO:0005829=ISS} cell cycle, regulation of bone mineralization, regulation of cell cycle, regulation of cell cycle process, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytosol, nuclear membrane protein heterodimerization activity, syntaxin binding Human UniProtKB:Q8BHN1 TXN IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0097068=GO_REF:0000019, GO:0030424=GO_REF:0000019, GO:0008283=PMID:3170595, GO:0007267=PMID:10947064, GO:0015035=GO_REF:0000002, GO:0006928=PMID:10947064, GO:0015037=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0048678=GO_REF:0000019, GO:0035872=Reactome:REACT_75913, GO:0030425=GO_REF:0000019, GO:0005829=Reactome:REACT_75816, GO:0005739=GO_REF:0000019, GO:0046826=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0033158=PMID:11118054, GO:0071333=GO_REF:0000019, GO:0009314=PMID:11118054, GO:0014823=GO_REF:0000019, GO:0015949=Reactome:REACT_21330, GO:0006662=GO_REF:0000002, GO:0071455=GO_REF:0000019, GO:0009055=GO_REF:0000002, GO:0010269=GO_REF:0000019, GO:0055086=Reactome:REACT_1698, GO:0005576=GO_REF:0000039, GO:0000122=GO_REF:0000019, GO:0035690=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0007165=PMID:10947064, GO:0016999=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0043388=PMID:11118054, GO:0005654=Reactome:REACT_1678, GO:0045454=GO_REF:0000019, GO:0071548=GO_REF:0000019, GO:0019899=GO_REF:0000019, GO:0022900=GO_REF:0000037, GO:0055114=PMID:11118054} P10599 Thioredoxin protein 20130415 {GO:0005515=IPI, GO:0097068=IEA, GO:0030424=IEA, GO:0008283=TAS, GO:0007267=TAS, GO:0015035=IEA, GO:0006928=TAS, GO:0015037=IEA, GO:0044281=TAS, GO:0048678=IEA, GO:0035872=TAS, GO:0030425=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0046826=IEA, GO:0043025=IEA, GO:0033158=IDA, GO:0071333=IEA, GO:0009314=IDA, GO:0014823=IEA, GO:0015949=TAS, GO:0006662=IEA, GO:0071455=IEA, GO:0009055=IEA, GO:0010269=IEA, GO:0055086=TAS, GO:0005576=IEA, GO:0000122=IEA, GO:0035690=IEA, GO:0006351=IEA, GO:0007165=TAS, GO:0016999=IEA, GO:0045087=TAS, GO:0043388=IDA, GO:0005654=TAS, GO:0045454=IEA, GO:0071548=IEA, GO:0019899=IEA, GO:0022900=IEA, GO:0055114=IDA} antibiotic metabolic process, cell proliferation, cell redox homeostasis, cell-cell signaling, cellular component movement, cellular response to drug, cellular response to glucose stimulus, cellular response to hyperoxia, electron transport chain, glycerol ether metabolic process, innate immune response, negative regulation of protein export from nucleus, negative regulation of transcription from RNA polymerase II promoter, nucleobase-containing small molecule interconversion, nucleobase-containing small molecule metabolic process, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, oxidation-reduction process, positive regulation of DNA binding, regulation of protein import into nucleus, translocation, response to activity, response to axon injury, response to dexamethasone stimulus, response to radiation, response to selenium ion, response to thyroxine stimulus, signal transduction, small molecule metabolic process, transcription, DNA-dependent axon, cytosol, dendrite, extracellular region, mitochondrion, neuronal cell body, nucleoplasm electron carrier activity, enzyme binding, peptide disulfide oxidoreductase activity, protein binding, protein disulfide oxidoreductase activity Human UniProtKB:Q99836 TXN2 HPA UniProtKB {GO:0001666=GO_REF:0000019, GO:0014070=GO_REF:0000019, GO:0007584=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0006662=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0015035=GO_REF:0000002, GO:0009055=GO_REF:0000002, GO:0048678=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0009749=GO_REF:0000019, GO:0005739=GO_REF:0000052, GO:0031669=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0045454=GO_REF:0000002, GO:0009725=GO_REF:0000019, GO:0022900=GO_REF:0000037, GO:0006979=GO_REF:0000019} Q99757 Thioredoxin, mitochondrial protein 20100326 {GO:0001666=IEA, GO:0014070=IEA, GO:0007584=IEA, GO:0042493=IEA, GO:0006662=IEA, GO:0005730=IDA, GO:0015035=IEA, GO:0009055=IEA, GO:0048678=IEA, GO:0032403=IEA, GO:0030425=IEA, GO:0009749=IEA, GO:0005739=IDA, GO:0031669=IEA, GO:0043025=IEA, GO:0045454=IEA, GO:0009725=IEA, GO:0022900=IEA, GO:0006979=IEA} cell redox homeostasis, cellular response to nutrient levels, electron transport chain, glycerol ether metabolic process, response to axon injury, response to drug, response to glucose stimulus, response to hormone stimulus, response to hypoxia, response to nutrient, response to organic cyclic compound, response to oxidative stress dendrite, mitochondrion, neuronal cell body, nucleolus electron carrier activity, protein complex binding, protein disulfide oxidoreductase activity Human TXNDC11 UniProtKB UniProtKB {GO:0005789=GO_REF:0000039, GO:0045454=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q6PKC3 Thioredoxin domain-containing protein 11 protein 20130413 {GO:0005789=IEA, GO:0045454=IEA, GO:0016021=IEA} cell redox homeostasis endoplasmic reticulum membrane, integral to membrane Human UniProtKB-SubCell:SL-0097 TXNDC12 UniProtKB UniProtKB {GO:0019153=GO_REF:0000003, GO:0005788=GO_REF:0000039, GO:0045454=GO_REF:0000002} O95881 Thioredoxin domain-containing protein 12 protein 20130413 {GO:0019153=IEA, GO:0005788=IEA, GO:0045454=IEA} cell redox homeostasis endoplasmic reticulum lumen protein-disulfide reductase (glutathione) activity Human UniProtKB-SubCell:SL-0096 TXNDC15 UniProtKB UniProtKB {GO:0045454=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q96J42 Thioredoxin domain-containing protein 15 protein 20130413 {GO:0045454=IEA, GO:0016021=IEA} cell redox homeostasis integral to membrane Human UniProtKB-KW:KW-0812 TXNDC17 UniProtKB UniProtKB {GO:0005515=PMID:14607844, GO:0004601=PMID:14607844, GO:0009055=PMID:15355959, GO:0047134=PMID:14607844, GO:0033209=PMID:14607844, GO:0005829=PMID:14607844} Q9BRA2 Thioredoxin domain-containing protein 17 protein 20080625 {GO:0005515=IPI, GO:0004601=IDA, GO:0009055=IDA, GO:0047134=IDA, GO:0033209=IMP, GO:0005829=IDA} tumor necrosis factor-mediated signaling pathway cytosol electron carrier activity, peroxidase activity, protein binding, protein-disulfide reductase activity Human TXNDC2 HPA UniProtKB {GO:0006662=GO_REF:0000002, GO:0045735=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0015035=GO_REF:0000002, GO:0009055=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0007275=GO_REF:0000037, GO:0007283=PMID:11399755, GO:0001520=GO_REF:0000019, GO:0030154=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0004791=PMID:11399755, GO:0045454=PMID:11399755} Q86VQ3 Thioredoxin domain-containing protein 2 protein 20111111 {GO:0006662=IEA, GO:0045735=IEA, GO:0005730=IDA, GO:0015035=IEA, GO:0009055=IEA, GO:0005634=IDA, GO:0007275=IEA, GO:0007283=NAS, GO:0001520=IEA, GO:0030154=IEA, GO:0005737=IDA, GO:0004791=IDA, GO:0045454=NAS} cell differentiation, cell redox homeostasis, glycerol ether metabolic process, multicellular organismal development, spermatogenesis cytoplasm, nucleolus, nucleus, outer dense fiber electron carrier activity, nutrient reservoir activity, protein disulfide oxidoreductase activity, thioredoxin-disulfide reductase activity Human TXNDC5 Reactome UniProtKB {GO:0043066=PMID:16130169, GO:0005783=PMID:16130169, GO:0006662=GO_REF:0000002, GO:0006892=Reactome:REACT_11235, GO:0015035=GO_REF:0000002, GO:0005788=GO_REF:0000039, GO:0009055=GO_REF:0000002, GO:0045454=GO_REF:0000002, GO:0016853=GO_REF:0000002, GO:0016044=Reactome:REACT_11123, GO:0043202=Reactome:REACT_19390} Q8NBS9 Thioredoxin domain-containing protein 5 protein 20090819 {GO:0043066=TAS, GO:0005783=TAS, GO:0006662=IEA, GO:0006892=TAS, GO:0015035=IEA, GO:0005788=IEA, GO:0009055=IEA, GO:0045454=IEA, GO:0016853=IEA, GO:0016044=TAS, GO:0043202=TAS} cell redox homeostasis, cellular membrane organization, glycerol ether metabolic process, negative regulation of apoptotic process, post-Golgi vesicle-mediated transport endoplasmic reticulum, endoplasmic reticulum lumen, lysosomal lumen electron carrier activity, isomerase activity, protein disulfide oxidoreductase activity Human TXNDC9 InterPro UniProtKB {GO:0005515=PMID:16169070, GO:0008150=GO_REF:0000015, GO:0005813=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0030496=GO_REF:0000019, GO:0045454=GO_REF:0000002, GO:0005634=GO_REF:0000019, GO:0005575=GO_REF:0000015} Q8TB70 Thioredoxin domain containing 9, isoform CRA_c protein 20130413 {GO:0005515=IPI, GO:0008150=ND, GO:0005813=IEA, GO:0005737=IEA, GO:0030496=IEA, GO:0045454=IEA, GO:0005634=IEA, GO:0005575=ND} biological_process, cell redox homeostasis cellular_component, centrosome, cytoplasm, midbody, nucleus protein binding Human InterPro:IPR013766 TXNIP Reactome UniProtKB {GO:0005515=PMID:14632196, GO:0042542=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0006606=GO_REF:0000019, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_75760, GO:0005758=GO_REF:0000019, GO:0005737=PMID:14632196, GO:0042127=GO_REF:0000019, GO:0051782=PMID:18541147, GO:0032355=GO_REF:0000019, GO:0031625=PMID:20068034, GO:0004857=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0009749=GO_REF:0000019, GO:0009612=GO_REF:0000019, GO:0051592=GO_REF:0000019, GO:0007049=GO_REF:0000037, GO:0030216=PMID:14632196, GO:0045087=Reactome:REACT_6802, GO:0032570=GO_REF:0000019, GO:0071228=PMID:18541147, GO:0048008=GO_REF:0000019} Q9H3M7 Thioredoxin-interacting protein protein 20110415 {GO:0005515=IPI, GO:0042542=IEA, GO:0005634=IEA, GO:0006606=IEA, GO:0035872=TAS, GO:0005829=TAS, GO:0005758=IEA, GO:0005737=IDA, GO:0042127=IEA, GO:0051782=IDA, GO:0032355=IEA, GO:0031625=IPI, GO:0004857=IEA, GO:0043065=IEA, GO:0042493=IEA, GO:0000122=IEA, GO:0006351=IEA, GO:0009749=IEA, GO:0009612=IEA, GO:0051592=IEA, GO:0007049=IEA, GO:0030216=IDA, GO:0045087=TAS, GO:0032570=IEA, GO:0071228=IDA, GO:0048008=IEA} cell cycle, cellular response to tumor cell, innate immune response, keratinocyte differentiation, negative regulation of cell division, negative regulation of transcription from RNA polymerase II promoter, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, platelet-derived growth factor receptor signaling pathway, positive regulation of apoptotic process, protein import into nucleus, regulation of cell proliferation, response to calcium ion, response to drug, response to estradiol stimulus, response to glucose stimulus, response to hydrogen peroxide, response to mechanical stimulus, response to progesterone stimulus, transcription, DNA-dependent cytoplasm, cytosol, mitochondrial intermembrane space, nucleus enzyme inhibitor activity, protein binding, ubiquitin protein ligase binding Human TXNL1 HPA UniProtKB {GO:0000502=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0006662=GO_REF:0000002, GO:0015035=GO_REF:0000002, GO:0015036=PMID:9668102, GO:0009055=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0045454=GO_REF:0000002, GO:0022900=GO_REF:0000037} O43396 Thioredoxin-like protein 1 protein 20080205 {GO:0000502=IEA, GO:0005737=IDA, GO:0006662=IEA, GO:0015035=IEA, GO:0015036=IDA, GO:0009055=IEA, GO:0005634=IEA, GO:0045454=IEA, GO:0022900=IEA} cell redox homeostasis, electron transport chain, glycerol ether metabolic process cytoplasm, nucleus, proteasome complex disulfide oxidoreductase activity, electron carrier activity, protein disulfide oxidoreductase activity Human TXNL4A BHF-UCL UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:15840814, GO:0010467=Reactome:REACT_71, GO:0000245=PMID:10610776, GO:0005737=PMID:18559850, GO:0007067=GO_REF:0000029, GO:0000398=Reactome:REACT_1753, GO:0000375=PMID:10610776, GO:0005654=Reactome:REACT_2241, GO:0005634=PMID:18559850, GO:0005681=PMID:10610776, GO:0051301=GO_REF:0000037} P83876 Thioredoxin-like protein 4A protein 20091028 {GO:0008380=TAS, GO:0005515=IPI, GO:0010467=TAS, GO:0000245=TAS, GO:0005737=IDA, GO:0007067=NAS, GO:0000398=TAS, GO:0000375=TAS, GO:0005654=TAS, GO:0005634=IDA, GO:0005681=TAS, GO:0051301=IEA} RNA splicing, RNA splicing, via transesterification reactions, cell division, gene expression, mRNA splicing, via spliceosome, mitosis, spliceosomal complex assembly cytoplasm, nucleoplasm, nucleus, spliceosomal complex protein binding Human UniProtKB:O95400 TXNL4B UniProtKB UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0007067=GO_REF:0000002, GO:0005681=GO_REF:0000002} Q9NX01 Thioredoxin-like protein 4B protein 20130413 {GO:0008380=IEA, GO:0006397=IEA, GO:0007067=IEA, GO:0005681=IEA} RNA splicing, mRNA processing, mitosis spliceosomal complex Human UniProtKB-KW:KW-0508 TXNRD1 HPA UniProtKB {GO:0050661=GO_REF:0000002, GO:0071280=GO_REF:0000019, GO:0008283=GO_REF:0000019, GO:0050660=GO_REF:0000002, GO:0015035=GO_REF:0000002, GO:0006749=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0070276=GO_REF:0000019, GO:0048678=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0005829=Reactome:REACT_115677, GO:0005739=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0043025=GO_REF:0000019, GO:0016174=GO_REF:0000019, GO:0042744=GO_REF:0000019, GO:0010942=GO_REF:0000019, GO:0044255=Reactome:REACT_22279, GO:0042191=GO_REF:0000019, GO:0016259=GO_REF:0000019, GO:0015949=Reactome:REACT_21330, GO:0001707=GO_REF:0000019, GO:0051262=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0071455=GO_REF:0000019, GO:0010269=GO_REF:0000019, GO:0042537=GO_REF:0000019, GO:0009055=GO_REF:0000002, GO:0055086=Reactome:REACT_1698, GO:0001890=GO_REF:0000019, GO:0045340=GO_REF:0000019, GO:0070995=GO_REF:0000019, GO:0007165=PMID:8921404, GO:0004791=Reactome:REACT_1609, GO:0045454=GO_REF:0000002, GO:0033797=GO_REF:0000019, GO:0022900=GO_REF:0000037} Q16881 Thioredoxin reductase 1, cytoplasmic protein 20101115 {GO:0050661=IEA, GO:0071280=IEA, GO:0008283=IEA, GO:0050660=IEA, GO:0015035=IEA, GO:0006749=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0070276=IEA, GO:0048678=IEA, GO:0042803=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0005737=IDA, GO:0043025=IEA, GO:0016174=IEA, GO:0042744=IEA, GO:0010942=IEA, GO:0044255=TAS, GO:0042191=IEA, GO:0016259=IEA, GO:0015949=TAS, GO:0001707=IEA, GO:0051262=IEA, GO:0042493=IEA, GO:0005730=IDA, GO:0071455=IEA, GO:0010269=IEA, GO:0042537=IEA, GO:0009055=IEA, GO:0055086=TAS, GO:0001890=IEA, GO:0045340=IEA, GO:0070995=IEA, GO:0007165=NAS, GO:0004791=EXP, GO:0045454=IEA, GO:0033797=IEA, GO:0022900=IEA} NADPH oxidation, benzene-containing compound metabolic process, cell proliferation, cell redox homeostasis, cellular lipid metabolic process, cellular response to copper ion, cellular response to hyperoxia, electron transport chain, glutathione metabolic process, halogen metabolic process, hydrogen peroxide catabolic process, mesoderm formation, methylmercury metabolic process, nucleobase-containing small molecule interconversion, nucleobase-containing small molecule metabolic process, placenta development, positive regulation of cell death, protein tetramerization, response to axon injury, response to drug, response to selenium ion, selenocysteine metabolic process, signal transduction, small molecule metabolic process cytoplasm, cytosol, mitochondrion, neuronal cell body, nucleolus, nucleus NAD(P)H oxidase activity, NADP binding, electron carrier activity, flavin adenine dinucleotide binding, mercury ion binding, protein disulfide oxidoreductase activity, protein homodimerization activity, selenate reductase activity, thioredoxin-disulfide reductase activity Human TXNRD2 HPA UniProtKB {GO:0005515=PMID:20413580, GO:0030097=GO_REF:0000019, GO:0007507=GO_REF:0000019, GO:0005739=GO_REF:0000052, GO:0050661=GO_REF:0000002, GO:0050660=GO_REF:0000002, GO:0000305=PMID:10455115, GO:0004791=GO_REF:0000024, GO:0045454=GO_REF:0000002} Q9NNW7 Thioredoxin reductase 2, mitochondrial protein 20101115 {GO:0005515=IPI, GO:0030097=IEA, GO:0007507=IEA, GO:0005739=IDA, GO:0050661=IEA, GO:0050660=IEA, GO:0000305=TAS, GO:0004791=ISS, GO:0045454=IEA} cell redox homeostasis, heart development, hemopoiesis, response to oxygen radical mitochondrion NADP binding, flavin adenine dinucleotide binding, protein binding, thioredoxin-disulfide reductase activity Human TXNRD3 UniProtKB UniProtKB {GO:0050661=GO_REF:0000002, GO:0005783=GO_REF:0000039, GO:0050660=GO_REF:0000002, GO:0015035=GO_REF:0000002, GO:0009055=GO_REF:0000002, GO:0007275=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0007283=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0005737=GO_REF:0000002, GO:0004791=PMID:10455115, GO:0045454=PMID:10455115, GO:0022900=GO_REF:0000037} Q86VQ6 Thioredoxin reductase 3 protein 20080417 {GO:0050661=IEA, GO:0005783=IEA, GO:0050660=IEA, GO:0015035=IEA, GO:0009055=IEA, GO:0007275=IEA, GO:0005634=IEA, GO:0007283=IEA, GO:0030154=IEA, GO:0005737=IEA, GO:0004791=NAS, GO:0045454=NAS, GO:0022900=IEA} cell differentiation, cell redox homeostasis, electron transport chain, multicellular organismal development, spermatogenesis cytoplasm, endoplasmic reticulum, nucleus NADP binding, electron carrier activity, flavin adenine dinucleotide binding, protein disulfide oxidoreductase activity, thioredoxin-disulfide reductase activity Human TYK2 BHF-UCL UniProtKB {GO:0005515=PMID:22939624, GO:0005131=PMID:10502458, GO:0019221=Reactome:REACT_25229, GO:0005634=PMID:10502458, GO:0005524=GO_REF:0000037, GO:0007243=GO_REF:0000002, GO:0005829=Reactome:REACT_25401, GO:0005737=PMID:10502458, GO:0004672=GO_REF:0000002, GO:0060337=Reactome:REACT_25162, GO:0016020=GO_REF:0000002, GO:0060338=Reactome:REACT_25216, GO:0006468=PMID:2216457, GO:0004713=Reactome:REACT_25383, GO:0005856=GO_REF:0000002, GO:0004715=GO_REF:0000003} P29597 Non-receptor tyrosine-protein kinase TYK2 protein 20081212 {GO:0005515=IPI, GO:0005131=IPI, GO:0019221=TAS, GO:0005634=IDA, GO:0005524=IEA, GO:0007243=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0004672=IEA, GO:0060337=TAS, GO:0016020=IEA, GO:0060338=TAS, GO:0006468=TAS, GO:0004713=TAS, GO:0005856=IEA, GO:0004715=IEA} cytokine-mediated signaling pathway, intracellular protein kinase cascade, protein phosphorylation, regulation of type I interferon-mediated signaling pathway, type I interferon-mediated signaling pathway cytoplasm, cytoskeleton, cytosol, membrane, nucleus ATP binding, growth hormone receptor binding, non-membrane spanning protein tyrosine kinase activity, protein binding, protein kinase activity, protein tyrosine kinase activity Human UniProtKB:P10912 TYMP Reactome UniProtKB {GO:0006213=GO_REF:0000002, GO:0009032=GO_REF:0000003, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0043097=Reactome:REACT_655, GO:0001525=GO_REF:0000037, GO:0006220=PMID:9924029, GO:0004645=GO_REF:0000002, GO:0005161=PMID:2005900, GO:0030154=GO_REF:0000037, GO:0005829=Reactome:REACT_2153, GO:0006260=PMID:9924029, GO:0016154=GO_REF:0000002, GO:0046135=Reactome:REACT_1023, GO:0006935=GO_REF:0000037, GO:0016763=Reactome:REACT_2153, GO:0006206=Reactome:REACT_957, GO:0008083=GO_REF:0000037, GO:0000002=PMID:9924029} P19971 Thymidine phosphorylase protein 20130213 {GO:0006213=IEA, GO:0009032=IEA, GO:0055086=TAS, GO:0044281=TAS, GO:0043097=TAS, GO:0001525=IEA, GO:0006220=TAS, GO:0004645=IEA, GO:0005161=TAS, GO:0030154=IEA, GO:0005829=TAS, GO:0006260=TAS, GO:0016154=IEA, GO:0046135=TAS, GO:0006935=IEA, GO:0016763=EXP, GO:0006206=TAS, GO:0008083=IEA, GO:0000002=TAS} DNA replication, angiogenesis, cell differentiation, chemotaxis, mitochondrial genome maintenance, nucleobase-containing small molecule metabolic process, pyrimidine nucleobase metabolic process, pyrimidine nucleoside catabolic process, pyrimidine nucleoside metabolic process, pyrimidine nucleoside salvage, pyrimidine nucleotide metabolic process, small molecule metabolic process cytosol growth factor activity, phosphorylase activity, platelet-derived growth factor receptor binding, pyrimidine-nucleoside phosphorylase activity, thymidine phosphorylase activity, transferase activity, transferring pentosyl groups Human TYMS Reactome UniProtKB {GO:0046683=PMID:16079077, GO:0051216=GO_REF:0000019, GO:0033189=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0060574=GO_REF:0000019, GO:0019860=GO_REF:0000019, GO:0048589=GO_REF:0000019, GO:0046134=Reactome:REACT_21376, GO:0000166=GO_REF:0000019, GO:0005759=PMID:21876188, GO:0048037=GO_REF:0000019, GO:0005976=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0006231=GO_REF:0000019, GO:0009636=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0046078=GO_REF:0000019, GO:0006235=GO_REF:0000041, GO:0051593=GO_REF:0000019, GO:0006139=PMID:2987839, GO:0006281=PMID:15504738, GO:0032570=GO_REF:0000019, GO:0007623=GO_REF:0000019, GO:0005654=Reactome:REACT_22145, GO:0000278=Reactome:REACT_152, GO:0045471=GO_REF:0000019, GO:0031100=GO_REF:0000019, GO:0005743=PMID:21876188, GO:0005634=PMID:21876188, GO:0044281=Reactome:REACT_111217, GO:0003729=GO_REF:0000019, GO:0004799=Reactome:REACT_1679, GO:0005829=Reactome:REACT_1679, GO:0005739=PMID:21876188, GO:0005542=GO_REF:0000019, GO:0005737=PMID:21876188, GO:0000082=Reactome:REACT_1783, GO:0000083=Reactome:REACT_683, GO:0008144=GO_REF:0000019, GO:0046653=GO_REF:0000019, GO:0034097=GO_REF:0000019, GO:0019088=GO_REF:0000019, GO:0009157=PMID:2987839, GO:0042493=GO_REF:0000019, GO:0048015=PMID:15504738, GO:0005730=GO_REF:0000019, GO:0055086=Reactome:REACT_1698, GO:0006260=PMID:15504738, GO:0006206=Reactome:REACT_957} P04818 Thymidylate synthase protein 20130213 {GO:0046683=IEP, GO:0051216=IEA, GO:0033189=IEA, GO:0042803=IEA, GO:0060574=IEA, GO:0019860=IEA, GO:0048589=IEA, GO:0046134=TAS, GO:0000166=IEA, GO:0005759=IDA, GO:0048037=IEA, GO:0005976=IEA, GO:0007568=IEA, GO:0006231=IEA, GO:0009636=IEA, GO:0051384=IEA, GO:0046078=IEA, GO:0006235=IEA, GO:0051593=IEA, GO:0006139=TAS, GO:0006281=NAS, GO:0032570=IEA, GO:0007623=IEA, GO:0005654=TAS, GO:0000278=TAS, GO:0045471=IEA, GO:0031100=IEA, GO:0005743=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0003729=IEA, GO:0004799=TAS, GO:0005829=TAS, GO:0005739=IDA, GO:0005542=IEA, GO:0005737=IDA, GO:0000082=TAS, GO:0000083=TAS, GO:0008144=IEA, GO:0046653=IEA, GO:0034097=IEA, GO:0019088=IEA, GO:0009157=TAS, GO:0042493=IEA, GO:0048015=NAS, GO:0005730=IEA, GO:0055086=TAS, GO:0006260=NAS, GO:0006206=TAS} DNA repair, DNA replication, G1/S transition of mitotic cell cycle, aging, cartilage development, circadian rhythm, dTMP biosynthetic process, dTTP biosynthetic process, dUMP metabolic process, deoxyribonucleoside monophosphate biosynthetic process, developmental growth, immortalization of host cell by virus, intestinal epithelial cell maturation, mitotic cell cycle, nucleobase-containing compound metabolic process, nucleobase-containing small molecule metabolic process, organ regeneration, phosphatidylinositol-mediated signaling, polysaccharide metabolic process, pyrimidine nucleobase metabolic process, pyrimidine nucleoside biosynthetic process, regulation of transcription involved in G1/S phase of mitotic cell cycle, response to cytokine stimulus, response to drug, response to ethanol, response to folic acid, response to glucocorticoid stimulus, response to organophosphorus, response to progesterone stimulus, response to toxic substance, response to vitamin A, small molecule metabolic process, tetrahydrofolate metabolic process, uracil metabolic process cytoplasm, cytosol, mitochondrial inner membrane, mitochondrial matrix, mitochondrion, nucleolus, nucleoplasm, nucleus cofactor binding, drug binding, folic acid binding, mRNA binding, nucleotide binding, protein homodimerization activity, thymidylate synthase activity Human TYR PINC UniProtKB {GO:0005515=PMID:16162817, GO:0033162=GO_REF:0000039, GO:0042470=GO_REF:0000024, GO:0048471=PMID:11092760, GO:0006726=PMID:7704033, GO:0046982=GO_REF:0000024, GO:0008283=GO_REF:0000019, GO:0005507=PMID:11092760, GO:0005798=PMID:10823941, GO:0048538=GO_REF:0000019, GO:0005764=PMID:11092760, GO:0042803=GO_REF:0000024, GO:0004503=PMID:11092760, GO:0005737=PMID:11092760, GO:0006583=PMID:7704033, GO:0016021=GO_REF:0000037, GO:0007601=PMID:7704033} P14679 Tyrosinase protein 20030904 {GO:0005515=IPI, GO:0033162=IEA, GO:0042470=ISS, GO:0048471=IDA, GO:0006726=TAS, GO:0046982=ISS, GO:0008283=IEA, GO:0005507=IMP, GO:0005798=TAS, GO:0048538=IEA, GO:0005764=TAS, GO:0042803=ISS, GO:0004503=IDA, GO:0005737=IDA, GO:0006583=TAS, GO:0016021=IEA, GO:0007601=TAS} cell proliferation, eye pigment biosynthetic process, melanin biosynthetic process from tyrosine, thymus development, visual perception Golgi-associated vesicle, cytoplasm, integral to membrane, lysosome, melanosome, melanosome membrane, perinuclear region of cytoplasm copper ion binding, monophenol monooxygenase activity, protein binding, protein heterodimerization activity, protein homodimerization activity Human TYRO3 GOC UniProtKB {GO:0005515=PMID:7634325, GO:0034122=GO_REF:0000024, GO:0060068=GO_REF:0000019, GO:0005634=GO_REF:0000024, GO:0042698=GO_REF:0000024, GO:0005635=GO_REF:0000024, GO:0007283=GO_REF:0000024, GO:0043524=GO_REF:0000024, GO:0046777=PMID:7537495, GO:0034446=GO_REF:0000024, GO:0001779=GO_REF:0000019, GO:0007155=PMID:8108112, GO:0045824=GO_REF:0000024, GO:0023014=PMID:7511603, GO:0046982=GO_REF:0000019, GO:0030168=GO_REF:0000024, GO:0043277=GO_REF:0000024, GO:0014065=PMID:10627473, GO:0005524=GO_REF:0000037, GO:0070527=GO_REF:0000024, GO:0007165=PMID:7511603, GO:0005887=PMID:7511603, GO:0050728=GO_REF:0000024, GO:0005789=GO_REF:0000024, GO:0043491=GO_REF:0000024, GO:0051250=GO_REF:0000019, GO:0021885=GO_REF:0000024, GO:0016021=GO_REF:0000038, GO:0004713=PMID:7537495, GO:0070050=GO_REF:0000024, GO:0004714=PMID:7511603, GO:0032940=GO_REF:0000024, GO:0004716=PMID:7511603, GO:0043548=PMID:10627473} Q06418 Tyrosine-protein kinase receptor TYRO3 protein 20130413 {GO:0005515=IPI, GO:0034122=ISS, GO:0060068=IEA, GO:0005634=ISS, GO:0042698=ISS, GO:0005635=ISS, GO:0007283=ISS, GO:0043524=ISS, GO:0046777=IDA, GO:0034446=ISS, GO:0001779=IEA, GO:0007155=NAS, GO:0045824=ISS, GO:0023014=NAS, GO:0046982=IEA, GO:0030168=ISS, GO:0043277=ISS, GO:0014065=NAS, GO:0005524=IEA, GO:0070527=ISS, GO:0007165=NAS, GO:0005887=NAS, GO:0050728=ISS, GO:0005789=ISS, GO:0043491=ISS, GO:0051250=IEA, GO:0021885=ISS, GO:0016021=IEA, GO:0004713=IDA, GO:0070050=ISS, GO:0004714=NAS, GO:0032940=ISS, GO:0004716=NAS, GO:0043548=IPI} apoptotic cell clearance, cell adhesion, forebrain cell migration, natural killer cell differentiation, negative regulation of inflammatory response, negative regulation of innate immune response, negative regulation of lymphocyte activation, negative regulation of neuron apoptotic process, negative regulation of toll-like receptor signaling pathway, neuron homeostasis, ovulation cycle, phosphatidylinositol 3-kinase cascade, platelet activation, platelet aggregation, protein autophosphorylation, protein kinase B signaling cascade, secretion by cell, signal transduction, signal transduction by phosphorylation, spermatogenesis, substrate adhesion-dependent cell spreading, vagina development endoplasmic reticulum membrane, integral to membrane, integral to plasma membrane, nuclear envelope, nucleus ATP binding, phosphatidylinositol 3-kinase binding, protein binding, protein heterodimerization activity, protein tyrosine kinase activity, receptor signaling protein tyrosine kinase activity, transmembrane receptor protein tyrosine kinase activity Human TYROBP IntAct UniProtKB {GO:0005515=PMID:20890284, GO:0005886=Reactome:REACT_147897, GO:0042802=PMID:20890284, GO:0035556=PMID:9490415, GO:0007165=PMID:9490415, GO:0006968=PMID:9490415, GO:0002281=GO_REF:0000019, GO:0007229=GO_REF:0000019, GO:0005887=PMID:9490415, GO:0007411=Reactome:REACT_18266, GO:0045087=Reactome:REACT_6802, GO:0050776=Reactome:REACT_11152, GO:0002283=GO_REF:0000019, GO:0005057=PMID:9490415} O43914 TYRO protein tyrosine kinase-binding protein protein 20130415 {GO:0005515=IPI, GO:0005886=TAS, GO:0042802=IPI, GO:0035556=TAS, GO:0007165=TAS, GO:0006968=TAS, GO:0002281=IEA, GO:0007229=IEA, GO:0005887=TAS, GO:0007411=TAS, GO:0045087=TAS, GO:0050776=TAS, GO:0002283=IEA, GO:0005057=TAS} axon guidance, cellular defense response, innate immune response, integrin-mediated signaling pathway, intracellular signal transduction, macrophage activation involved in immune response, neutrophil activation involved in immune response, regulation of immune response, signal transduction integral to plasma membrane, plasma membrane identical protein binding, protein binding, receptor signaling protein activity Human UniProtKB:O43914 TYRP1 InterPro UniProtKB {GO:0005515=PMID:19841138, GO:0033162=GO_REF:0000002, GO:0042470=GO_REF:0000024, GO:0046982=GO_REF:0000024, GO:0005507=GO_REF:0000002, GO:0043438=GO_REF:0000019, GO:0032438=GO_REF:0000019, GO:0030318=GO_REF:0000019, GO:0042803=GO_REF:0000024, GO:0042438=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0016716=GO_REF:0000002, GO:0030669=PMID:19841138, GO:0010008=PMID:19841138} Q5W0M5 5,6-dihydroxyindole-2-carboxylic acid oxidase protein 20130413 {GO:0005515=IPI, GO:0033162=IEA, GO:0042470=ISS, GO:0046982=ISS, GO:0005507=IEA, GO:0043438=IEA, GO:0032438=IEA, GO:0030318=IEA, GO:0042803=ISS, GO:0042438=IEA, GO:0016021=IEA, GO:0016716=IEA, GO:0030669=IDA, GO:0010008=IDA} acetoacetic acid metabolic process, melanin biosynthetic process, melanocyte differentiation, melanosome organization clathrin-coated endocytic vesicle membrane, endosome membrane, integral to membrane, melanosome, melanosome membrane copper ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen, protein binding, protein heterodimerization activity, protein homodimerization activity Human InterPro:IPR015559 TYSND1 UniProtKB UniProtKB {GO:0004252=PMID:22002062, GO:0031998=PMID:22002062, GO:0016485=PMID:22002062, GO:0006508=PMID:22002062, GO:0051260=PMID:22002062, GO:0002020=PMID:22002062, GO:0005777=PMID:22002062} Q2T9J0 Peroxisomal leader peptide-processing protease protein 20111115 {GO:0004252=IMP, GO:0031998=IMP, GO:0016485=IMP, GO:0006508=IMP, GO:0051260=IDA, GO:0002020=IPI, GO:0005777=IDA} protein homooligomerization, protein processing, proteolysis, regulation of fatty acid beta-oxidation peroxisome protease binding, serine-type endopeptidase activity Human TYW1 UniProtKB UniProtKB {GO:0051539=GO_REF:0000037, GO:0005506=GO_REF:0000002, GO:0010181=GO_REF:0000002, GO:0016491=GO_REF:0000002, GO:0008033=GO_REF:0000037} Q9NV66 tRNA wybutosine-synthesizing protein 1 homolog protein 20130413 {GO:0051539=IEA, GO:0005506=IEA, GO:0010181=IEA, GO:0016491=IEA, GO:0008033=IEA} tRNA processing 4 iron, 4 sulfur cluster binding, FMN binding, iron ion binding, oxidoreductase activity Human UniProtKB-KW:KW-0004 TYW1B UniProtKB UniProtKB {GO:0051539=GO_REF:0000037, GO:0005506=GO_REF:0000002, GO:0010181=GO_REF:0000002, GO:0016491=GO_REF:0000002, GO:0008033=GO_REF:0000037} Q6NUM6 tRNA wybutosine-synthesizing protein 1 homolog B protein 20130413 {GO:0051539=IEA, GO:0005506=IEA, GO:0010181=IEA, GO:0016491=IEA, GO:0008033=IEA} tRNA processing 4 iron, 4 sulfur cluster binding, FMN binding, iron ion binding, oxidoreductase activity Human UniProtKB-KW:KW-0004 U2AF1 HPA UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:21988832, GO:0006397=PMID:1388271, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0015030=PMID:1388271, GO:0006366=Reactome:REACT_1366, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0031124=Reactome:REACT_1849, GO:0005634=GO_REF:0000052, GO:0050733=GO_REF:0000019, GO:0071013=PMID:11991638, GO:0006406=Reactome:REACT_1597, GO:0000166=GO_REF:0000002, GO:0016607=GO_REF:0000024, GO:0000398=Reactome:REACT_467, GO:0005654=Reactome:REACT_1935, GO:0008270=GO_REF:0000002, GO:0005681=PMID:9731529} Q01081 Splicing factor U2AF 35 kDa subunit protein 20111111 {GO:0008380=TAS, GO:0005515=IPI, GO:0006397=TAS, GO:0010467=TAS, GO:0006369=TAS, GO:0015030=TAS, GO:0006366=TAS, GO:0003723=IEA, GO:0005730=IDA, GO:0031124=TAS, GO:0005634=IDA, GO:0050733=IEA, GO:0071013=IDA, GO:0006406=TAS, GO:0000166=IEA, GO:0016607=ISS, GO:0000398=TAS, GO:0005654=TAS, GO:0008270=IEA, GO:0005681=IDA} RNA splicing, gene expression, mRNA 3'-end processing, mRNA export from nucleus, mRNA processing, mRNA splicing, via spliceosome, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter Cajal body, catalytic step 2 spliceosome, nuclear speck, nucleolus, nucleoplasm, nucleus, spliceosomal complex RNA binding, RS domain binding, nucleotide binding, protein binding, zinc ion binding NOT Human U2AF1L4 UniProtKB UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0016607=GO_REF:0000039, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005681=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000002} Q8WU68 Splicing factor U2AF 26 kDa subunit protein 20130413 {GO:0008380=IEA, GO:0006397=IEA, GO:0016607=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0005681=IEA, GO:0008270=IEA, GO:0005634=IEA} RNA splicing, mRNA processing nuclear speck, nucleus, spliceosomal complex RNA binding, nucleotide binding, zinc ion binding Human UniProtKB-SubCell:SL-0186 U2AF2 IntAct UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0006397=PMID:1538748, GO:0005515=PMID:21988832, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0048025=PMID:15009664, GO:0006366=Reactome:REACT_1366, GO:0003723=GO_REF:0000037, GO:0031124=Reactome:REACT_1849, GO:0005634=GO_REF:0000002, GO:0006406=Reactome:REACT_1597, GO:0000166=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0005681=PMID:9731529, GO:0005654=Reactome:REACT_1935, GO:0070742=GO_REF:0000019, GO:0019899=PMID:19574390} P26368 Splicing factor U2AF 65 kDa subunit protein 20130415 {GO:0008380=TAS, GO:0006397=TAS, GO:0005515=IPI, GO:0010467=TAS, GO:0006369=TAS, GO:0048025=IDA, GO:0006366=TAS, GO:0003723=IEA, GO:0031124=TAS, GO:0005634=IEA, GO:0006406=TAS, GO:0000166=IEA, GO:0000398=TAS, GO:0005681=IDA, GO:0005654=TAS, GO:0070742=IEA, GO:0019899=IPI} RNA splicing, gene expression, mRNA 3'-end processing, mRNA export from nucleus, mRNA processing, mRNA splicing, via spliceosome, negative regulation of mRNA splicing, via spliceosome, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter nucleoplasm, nucleus, spliceosomal complex C2H2 zinc finger domain binding, RNA binding, enzyme binding, nucleotide binding, protein binding Human UniProtKB:Q01081 U2SURP HPA UniProtKB {GO:0005515=PMID:20858735, GO:0006396=GO_REF:0000002, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002} O15042 U2 snRNP-associated SURP motif-containing protein protein 20110516 {GO:0005515=IPI, GO:0006396=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA} RNA processing nucleolus, nucleus RNA binding, nucleic acid binding, nucleotide binding, protein binding NOT Human UACA HPA UniProtKB {GO:0005515=PMID:17003112, GO:0048471=GO_REF:0000019, GO:0042347=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0008630=GO_REF:0000019, GO:0008631=GO_REF:0000019, GO:0005576=PMID:11162650, GO:0005634=GO_REF:0000052, GO:0005635=GO_REF:0000019, GO:0005739=GO_REF:0000052, GO:0043280=GO_REF:0000019, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0016020=GO_REF:0000019, GO:0043293=GO_REF:0000019, GO:0050728=GO_REF:0000019, GO:0042307=GO_REF:0000019, GO:0005856=GO_REF:0000039, GO:0009411=GO_REF:0000019} Q9BZF9 Uveal autoantigen with coiled-coil domains and ankyrin repeats protein 20111111 {GO:0005515=IPI, GO:0048471=IEA, GO:0042347=IEA, GO:0043065=IEA, GO:0008630=IEA, GO:0008631=IEA, GO:0005576=NAS, GO:0005634=IDA, GO:0005635=IEA, GO:0005739=IDA, GO:0043280=IEA, GO:0008150=ND, GO:0003674=ND, GO:0005737=IDA, GO:0016020=IEA, GO:0043293=IEA, GO:0050728=IEA, GO:0042307=IEA, GO:0005856=IEA, GO:0009411=IEA} biological_process, intrinsic apoptotic signaling pathway in response to DNA damage, intrinsic apoptotic signaling pathway in response to oxidative stress, negative regulation of NF-kappaB import into nucleus, negative regulation of inflammatory response, positive regulation of apoptotic process, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of protein import into nucleus, response to UV apoptosome, cytoplasm, cytoskeleton, extracellular region, membrane, mitochondrion, nuclear envelope, nucleus, perinuclear region of cytoplasm molecular_function, protein binding Human UAP1 HPA UniProtKB {GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006047=GO_REF:0000019, GO:0006048=Reactome:REACT_22394, GO:0005829=Reactome:REACT_22397, GO:0005737=GO_REF:0000052, GO:0003977=Reactome:REACT_22397, GO:0030246=GO_REF:0000019, GO:0006488=Reactome:REACT_22433, GO:0044267=Reactome:REACT_17015, GO:0018279=Reactome:REACT_22426, GO:0043687=Reactome:REACT_22161} Q16222 UDP-N-acetylhexosamine pyrophosphorylase protein 20101115 {GO:0005886=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0006047=IEA, GO:0006048=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0003977=TAS, GO:0030246=IEA, GO:0006488=TAS, GO:0044267=TAS, GO:0018279=TAS, GO:0043687=TAS} UDP-N-acetylglucosamine biosynthetic process, UDP-N-acetylglucosamine metabolic process, cellular protein metabolic process, dolichol-linked oligosaccharide biosynthetic process, post-translational protein modification, protein N-linked glycosylation via asparagine cytoplasm, cytosol, nucleolus, nucleus, plasma membrane UDP-N-acetylglucosamine diphosphorylase activity, carbohydrate binding Human UBA1 InterPro UniProtKB {GO:0005515=PMID:22190034, GO:0008219=GO_REF:0000037, GO:0016567=GO_REF:0000041, GO:0016874=GO_REF:0000037, GO:0008641=GO_REF:0000002, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0006464=GO_REF:0000002} Q5JRS3 Ubiquitin-like modifier-activating enzyme 1 protein 20130413 {GO:0005515=IPI, GO:0008219=IEA, GO:0016567=IEA, GO:0016874=IEA, GO:0008641=IEA, GO:0003824=IEA, GO:0005524=IEA, GO:0006464=IEA} cell death, cellular protein modification process, protein ubiquitination ATP binding, catalytic activity, ligase activity, protein binding, small protein activating enzyme activity Human InterPro:IPR000594 UBA2 GOC UniProtKB {GO:0005515=PMID:16189514, GO:0046982=PMID:20164921, GO:0016874=GO_REF:0000037, GO:0016925=PMID:20164921, GO:0005634=GO_REF:0000039, GO:0008641=GO_REF:0000002, GO:0043085=PMID:10187858, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0019948=PMID:20164921, GO:0008047=PMID:10187858, GO:0006464=GO_REF:0000002, GO:0008134=GO_REF:0000019} Q9UBT2 SUMO-activating enzyme subunit 2 protein 20130413 {GO:0005515=IPI, GO:0046982=IPI, GO:0016874=IEA, GO:0016925=IDA, GO:0005634=IEA, GO:0008641=IEA, GO:0043085=TAS, GO:0003824=IEA, GO:0005524=IEA, GO:0046872=IEA, GO:0019948=IDA, GO:0008047=TAS, GO:0006464=IEA, GO:0008134=IEA} cellular protein modification process, positive regulation of catalytic activity, protein sumoylation nucleus ATP binding, SUMO activating enzyme activity, catalytic activity, enzyme activator activity, ligase activity, metal ion binding, protein binding, protein heterodimerization activity, small protein activating enzyme activity, transcription factor binding Human UBA3 IntAct UniProtKB {GO:0005515=PMID:19549727, GO:0016922=GO_REF:0000019, GO:0016881=GO_REF:0000002, GO:0046982=PMID:12740388, GO:0045116=GO_REF:0000041, GO:0005634=GO_REF:0000054, GO:0008641=GO_REF:0000002, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0007113=GO_REF:0000019, GO:0006508=PMID:9694792, GO:0051726=GO_REF:0000019, GO:0045892=GO_REF:0000019, GO:0019781=GO_REF:0000019, GO:0006464=PMID:9694792} Q8TBC4 NEDD8-activating enzyme E1 catalytic subunit protein 20130415 {GO:0005515=IPI, GO:0016922=IEA, GO:0016881=IEA, GO:0046982=IPI, GO:0045116=IEA, GO:0005634=IDA, GO:0008641=IEA, GO:0003824=IEA, GO:0005524=IEA, GO:0007113=IEA, GO:0006508=TAS, GO:0051726=IEA, GO:0045892=IEA, GO:0019781=IEA, GO:0006464=TAS} cellular protein modification process, endomitotic cell cycle, negative regulation of transcription, DNA-dependent, protein neddylation, proteolysis, regulation of cell cycle nucleus ATP binding, NEDD8 activating enzyme activity, acid-amino acid ligase activity, catalytic activity, ligand-dependent nuclear receptor binding, protein binding, protein heterodimerization activity, small protein activating enzyme activity Human UniProtKB:P61081 UBA5 HPA UniProtKB {GO:0005515=PMID:20562859, GO:0005737=GO_REF:0000052, GO:0048037=GO_REF:0000002, GO:0071566=PMID:15071506, GO:0016235=GO_REF:0000052, GO:0071569=PMID:15071506, GO:0005634=GO_REF:0000039, GO:0003824=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0016616=GO_REF:0000002} Q9GZZ9 Ubiquitin-like modifier-activating enzyme 5 protein 20101115 {GO:0005515=IPI, GO:0005737=IDA, GO:0048037=IEA, GO:0071566=IDA, GO:0016235=IDA, GO:0071569=IDA, GO:0005634=IEA, GO:0003824=IEA, GO:0005524=IEA, GO:0046872=IEA, GO:0043231=IDA, GO:0016616=IEA} protein ufmylation aggresome, cytoplasm, intracellular membrane-bounded organelle, nucleus ATP binding, UFM1 activating enzyme activity, catalytic activity, cofactor binding, metal ion binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, protein binding Human UBA52 BHF-UCL UniProtKB {GO:0005515=PMID:15936278, GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0007220=Reactome:REACT_2001, GO:0006367=Reactome:REACT_12627, GO:0019221=Reactome:REACT_25229, GO:0007249=Reactome:REACT_25351, GO:0019058=Reactome:REACT_6167, GO:0051403=Reactome:REACT_21308, GO:0006412=Reactome:REACT_1014, GO:0006413=Reactome:REACT_2159, GO:0006414=Reactome:REACT_1477, GO:0002756=Reactome:REACT_6809, GO:0034220=Reactome:REACT_25300, GO:0007219=Reactome:REACT_118859, GO:0007173=Reactome:REACT_9417, GO:0002755=Reactome:REACT_27215, GO:0007179=Reactome:REACT_120850, GO:0043123=Reactome:REACT_24918, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0034134=Reactome:REACT_7980, GO:0042059=Reactome:REACT_12484, GO:0033554=Reactome:REACT_120956, GO:0000122=Reactome:REACT_121111, GO:0019068=Reactome:REACT_6818, GO:0002224=Reactome:REACT_9020, GO:0046788=Reactome:REACT_115893, GO:0006281=Reactome:REACT_216, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0000075=Reactome:REACT_1538, GO:0035666=Reactome:REACT_25281, GO:0034166=Reactome:REACT_9027, GO:0005654=Reactome:REACT_121374, GO:0000278=Reactome:REACT_152, GO:0044267=Reactome:REACT_17015, GO:0034162=Reactome:REACT_9047, GO:0010008=Reactome:REACT_115855, GO:0016044=Reactome:REACT_11123, GO:0050852=Reactome:REACT_12526, GO:0022415=Reactome:REACT_6361, GO:0034142=Reactome:REACT_6894, GO:0070423=Reactome:REACT_75776, GO:0061418=Reactome:REACT_120815, GO:0031145=Reactome:REACT_6871, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_160256, GO:0000084=Reactome:REACT_899, GO:0000187=Reactome:REACT_21399, GO:0000082=Reactome:REACT_1783, GO:0051092=Reactome:REACT_21281, GO:0000184=Reactome:REACT_75886, GO:0045944=Reactome:REACT_120734, GO:0000087=Reactome:REACT_910, GO:0016197=Reactome:REACT_27258, GO:0016032=Reactome:REACT_6256, GO:0032481=Reactome:REACT_147841, GO:0000080=Reactome:REACT_1590, GO:0032480=Reactome:REACT_25271, GO:0034138=Reactome:REACT_6783, GO:0030512=Reactome:REACT_120727, GO:0048011=Reactome:REACT_13776, GO:0043066=Reactome:REACT_13537, GO:0003735=GO_REF:0000002, GO:0006614=Reactome:REACT_115902, GO:0019083=Reactome:REACT_6152, GO:0019082=Reactome:REACT_115860, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0007254=Reactome:REACT_21368, GO:0071456=Reactome:REACT_121311, GO:0006915=Reactome:REACT_13643, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0006415=Reactome:REACT_1986, GO:0097190=Reactome:REACT_13720, GO:0055085=Reactome:REACT_15518, GO:0051439=Reactome:REACT_6837, GO:0006351=Reactome:REACT_121061, GO:0030666=Reactome:REACT_27184, GO:0005840=GO_REF:0000037, GO:0002479=Reactome:REACT_111178, GO:0034146=Reactome:REACT_9061, GO:0000090=Reactome:REACT_1275, GO:0006464=PMID:2581967} P62987 Ubiquitin-60S ribosomal protein L40 protein 20091209 {GO:0005515=IPI, GO:0002474=TAS, GO:0010467=TAS, GO:0007220=TAS, GO:0006367=TAS, GO:0019221=TAS, GO:0007249=TAS, GO:0019058=TAS, GO:0051403=TAS, GO:0006412=TAS, GO:0006413=TAS, GO:0006414=TAS, GO:0002756=TAS, GO:0034220=TAS, GO:0007219=TAS, GO:0007173=TAS, GO:0002755=TAS, GO:0007179=TAS, GO:0043123=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0038124=TAS, GO:0038123=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0034134=TAS, GO:0042059=TAS, GO:0033554=TAS, GO:0000122=TAS, GO:0019068=TAS, GO:0002224=TAS, GO:0046788=TAS, GO:0006281=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0000075=TAS, GO:0035666=TAS, GO:0034166=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0044267=TAS, GO:0034162=TAS, GO:0010008=TAS, GO:0016044=TAS, GO:0050852=TAS, GO:0022415=TAS, GO:0034142=TAS, GO:0070423=TAS, GO:0061418=TAS, GO:0031145=TAS, GO:0035872=TAS, GO:0005829=TAS, GO:0000084=TAS, GO:0000187=TAS, GO:0000082=TAS, GO:0051092=TAS, GO:0000184=TAS, GO:0045944=TAS, GO:0000087=TAS, GO:0016197=TAS, GO:0016032=TAS, GO:0032481=TAS, GO:0000080=TAS, GO:0032480=TAS, GO:0034138=TAS, GO:0030512=TAS, GO:0048011=TAS, GO:0043066=TAS, GO:0003735=IEA, GO:0006614=TAS, GO:0019083=TAS, GO:0019082=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0007254=TAS, GO:0071456=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0006415=TAS, GO:0097190=TAS, GO:0055085=TAS, GO:0051439=TAS, GO:0006351=TAS, GO:0030666=TAS, GO:0005840=IEA, GO:0002479=TAS, GO:0034146=TAS, GO:0000090=TAS, GO:0006464=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, DNA repair, G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, I-kappaB kinase/NF-kappaB cascade, JNK cascade, M phase of mitotic cell cycle, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, Notch receptor processing, Notch signaling pathway, RNA metabolic process, S phase of mitotic cell cycle, SRP-dependent cotranslational protein targeting to membrane, T cell receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, activation of MAPK activity, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, apoptotic signaling pathway, cell cycle checkpoint, cellular membrane organization, cellular protein metabolic process, cellular protein modification process, cellular response to hypoxia, cellular response to stress, cytokine-mediated signaling pathway, egress of virus within host cell, endosomal transport, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, gene expression, innate immune response, ion transmembrane transport, mRNA metabolic process, mitotic anaphase, mitotic cell cycle, negative regulation of apoptotic process, negative regulation of epidermal growth factor receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transforming growth factor beta receptor signaling pathway, negative regulation of type I interferon production, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, neurotrophin TRK receptor signaling pathway, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, nucleotide-binding oligomerization domain containing signaling pathway, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, positive regulation of type I interferon production, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, regulation of apoptotic process, regulation of transcription from RNA polymerase II promoter in response to hypoxia, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, translation, translational elongation, translational initiation, translational termination, transmembrane transport, viral infectious cycle, viral protein processing, viral reproduction, viral reproductive process, viral transcription, virion assembly cytosol, endocytic vesicle membrane, endosome membrane, nucleoplasm, ribosome protein binding, structural constituent of ribosome Human UniProtKB:P25686-3 UBA6 InterPro UniProtKB {GO:0005515=PMID:17889673, GO:0006511=PMID:17889673, GO:0005737=GO_REF:0000054, GO:0016567=PMID:17889673, GO:0016874=GO_REF:0000037, GO:0008641=GO_REF:0000002, GO:0019780=PMID:17889673, GO:0005524=GO_REF:0000002, GO:0006464=GO_REF:0000002} H0Y9U5 Ubiquitin-like modifier-activating enzyme 6 protein 20130413 {GO:0005515=IPI, GO:0006511=IMP, GO:0005737=IDA, GO:0016567=IMP, GO:0016874=IEA, GO:0008641=IEA, GO:0019780=IMP, GO:0005524=IEA, GO:0006464=IEA} cellular protein modification process, protein ubiquitination, ubiquitin-dependent protein catabolic process cytoplasm ATP binding, FAT10 activating enzyme activity, ligase activity, protein binding, small protein activating enzyme activity Human InterPro:IPR000127 UBA7 Reactome UniProtKB {GO:0016567=GO_REF:0000041, GO:0032020=PMID:16428300, GO:0045087=Reactome:REACT_6802, GO:0019941=GO_REF:0000019, GO:0016874=GO_REF:0000037, GO:0019221=Reactome:REACT_25229, GO:0032480=Reactome:REACT_25271, GO:0005524=GO_REF:0000037, GO:0006464=PMID:16428300, GO:0005829=Reactome:REACT_116132, GO:0019782=PMID:16428300} P41226 Ubiquitin-like modifier-activating enzyme 7 protein 20130301 {GO:0016567=IEA, GO:0032020=IDA, GO:0045087=TAS, GO:0019941=IEA, GO:0016874=IEA, GO:0019221=TAS, GO:0032480=TAS, GO:0005524=IEA, GO:0006464=IDA, GO:0005829=TAS, GO:0019782=IDA} ISG15-protein conjugation, cellular protein modification process, cytokine-mediated signaling pathway, innate immune response, modification-dependent protein catabolic process, negative regulation of type I interferon production, protein ubiquitination cytosol ATP binding, ISG15 activating enzyme activity, ligase activity Human UBAC1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0016567=GO_REF:0000041, GO:0005886=GO_REF:0000052} Q9BSL1 Ubiquitin-associated domain-containing protein 1 protein 20101115 {GO:0005737=IDA, GO:0005794=IDA, GO:0016567=IEA, GO:0005886=IDA} protein ubiquitination Golgi apparatus, cytoplasm, plasma membrane Human UBAC2 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8NBM4 Ubiquitin-associated domain-containing protein 2 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 UBAP1 LIFEdb UniProtKB {GO:0005737=GO_REF:0000054} Q9NZ09 Ubiquitin-associated protein 1 protein 20100607 {GO:0005737=IDA} cytoplasm Human UBAP2 null null {} null null null null {} null null null UBAP2L BHF-UCL UniProtKB {GO:0005515=PMID:19945174, GO:0005671=PMID:18838386, GO:0007339=PMID:19945174} Q14157 Ubiquitin-associated protein 2-like protein 20101105 {GO:0005515=IPI, GO:0005671=IDA, GO:0007339=IMP} binding of sperm to zona pellucida Ada2/Gcn5/Ada3 transcription activator complex protein binding colocalizes_with Human UBASH3A UniProtKB UniProtKB {GO:0016070=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003824=GO_REF:0000002, GO:0001817=GO_REF:0000019, GO:0050860=GO_REF:0000019, GO:0005829=PMID:16780588} P57075 Ubiquitin-associated and SH3 domain-containing protein A protein 20081007 {GO:0016070=IEA, GO:0005634=IEA, GO:0003824=IEA, GO:0001817=IEA, GO:0050860=IEA, GO:0005829=IDA} RNA metabolic process, negative regulation of T cell receptor signaling pathway, regulation of cytokine production cytosol, nucleus catalytic activity Human UBASH3B UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0004725=GO_REF:0000003} Q8TF42 Ubiquitin-associated and SH3 domain-containing protein B protein 20130413 {GO:0005737=IEA, GO:0005634=IEA, GO:0004725=IEA} cytoplasm, nucleus protein tyrosine phosphatase activity Human UniProtKB-SubCell:SL-0086 UBB IntAct UniProtKB {GO:0005515=PMID:18313049, GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0010992=GO_REF:0000019, GO:0006367=Reactome:REACT_12627, GO:0007220=Reactome:REACT_2001, GO:0019221=Reactome:REACT_25229, GO:0007249=Reactome:REACT_25351, GO:0051403=Reactome:REACT_21308, GO:0002756=Reactome:REACT_6809, GO:0034220=Reactome:REACT_25300, GO:0007173=Reactome:REACT_9417, GO:0007219=Reactome:REACT_118859, GO:0002755=Reactome:REACT_27215, GO:0007179=Reactome:REACT_120850, GO:0043123=Reactome:REACT_24918, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0034134=Reactome:REACT_7980, GO:0042059=Reactome:REACT_12484, GO:0033554=Reactome:REACT_120956, GO:0000122=Reactome:REACT_121111, GO:0019068=Reactome:REACT_6818, GO:0002224=Reactome:REACT_9020, GO:0046788=Reactome:REACT_115893, GO:0007144=GO_REF:0000019, GO:0006281=Reactome:REACT_216, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0021888=GO_REF:0000019, GO:0000075=Reactome:REACT_1538, GO:0035666=Reactome:REACT_25281, GO:0034166=Reactome:REACT_9027, GO:0005654=Reactome:REACT_121374, GO:0000278=Reactome:REACT_152, GO:0034162=Reactome:REACT_9047, GO:0007141=GO_REF:0000019, GO:0010008=Reactome:REACT_115855, GO:0016044=Reactome:REACT_11123, GO:0050852=Reactome:REACT_12526, GO:0022415=Reactome:REACT_6361, GO:0034142=Reactome:REACT_6894, GO:0070423=Reactome:REACT_75776, GO:0061418=Reactome:REACT_120815, GO:0031145=Reactome:REACT_6871, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_160256, GO:0000084=Reactome:REACT_899, GO:0000187=Reactome:REACT_21399, GO:0000082=Reactome:REACT_1783, GO:0051092=Reactome:REACT_21281, GO:0045944=Reactome:REACT_120734, GO:0000087=Reactome:REACT_910, GO:0016197=Reactome:REACT_27258, GO:0016032=Reactome:REACT_6256, GO:0032481=Reactome:REACT_147841, GO:0000080=Reactome:REACT_1590, GO:0034138=Reactome:REACT_6783, GO:0032480=Reactome:REACT_25271, GO:0030512=Reactome:REACT_120727, GO:0048011=Reactome:REACT_13776, GO:0043066=Reactome:REACT_13537, GO:0019082=Reactome:REACT_115860, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0007254=Reactome:REACT_21368, GO:0071456=Reactome:REACT_121311, GO:0006915=Reactome:REACT_13643, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0097190=Reactome:REACT_13720, GO:0055085=Reactome:REACT_15518, GO:0051439=Reactome:REACT_6837, GO:0006351=Reactome:REACT_121061, GO:0030666=Reactome:REACT_27184, GO:0097009=GO_REF:0000019, GO:0008585=GO_REF:0000019, GO:0072520=GO_REF:0000019, GO:0002479=Reactome:REACT_111178, GO:0060613=GO_REF:0000019, GO:0034146=Reactome:REACT_9061, GO:0000090=Reactome:REACT_1275} P0CG47 Polyubiquitin-B protein 20130415 {GO:0005515=IPI, GO:0002474=TAS, GO:0010467=TAS, GO:0010992=IEA, GO:0006367=TAS, GO:0007220=TAS, GO:0019221=TAS, GO:0007249=TAS, GO:0051403=TAS, GO:0002756=TAS, GO:0034220=TAS, GO:0007173=TAS, GO:0007219=TAS, GO:0002755=TAS, GO:0007179=TAS, GO:0043123=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0038124=TAS, GO:0038123=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0034134=TAS, GO:0042059=TAS, GO:0033554=TAS, GO:0000122=TAS, GO:0019068=TAS, GO:0002224=TAS, GO:0046788=TAS, GO:0007144=IEA, GO:0006281=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0021888=IEA, GO:0000075=TAS, GO:0035666=TAS, GO:0034166=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0034162=TAS, GO:0007141=IEA, GO:0010008=TAS, GO:0016044=TAS, GO:0050852=TAS, GO:0022415=TAS, GO:0034142=TAS, GO:0070423=TAS, GO:0061418=TAS, GO:0031145=TAS, GO:0035872=TAS, GO:0005829=TAS, GO:0000084=TAS, GO:0000187=TAS, GO:0000082=TAS, GO:0051092=TAS, GO:0045944=TAS, GO:0000087=TAS, GO:0016197=TAS, GO:0016032=TAS, GO:0032481=TAS, GO:0000080=TAS, GO:0034138=TAS, GO:0032480=TAS, GO:0030512=TAS, GO:0048011=TAS, GO:0043066=TAS, GO:0019082=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0007254=TAS, GO:0071456=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0097190=TAS, GO:0055085=TAS, GO:0051439=TAS, GO:0006351=TAS, GO:0030666=TAS, GO:0097009=IEA, GO:0008585=IEA, GO:0072520=IEA, GO:0002479=TAS, GO:0060613=IEA, GO:0034146=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, DNA repair, G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, I-kappaB kinase/NF-kappaB cascade, JNK cascade, M phase of mitotic cell cycle, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, Notch receptor processing, Notch signaling pathway, RNA metabolic process, S phase of mitotic cell cycle, T cell receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, activation of MAPK activity, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, apoptotic signaling pathway, cell cycle checkpoint, cellular membrane organization, cellular response to hypoxia, cellular response to stress, cytokine-mediated signaling pathway, egress of virus within host cell, endosomal transport, energy homeostasis, epidermal growth factor receptor signaling pathway, fat pad development, female gonad development, female meiosis I, fibroblast growth factor receptor signaling pathway, gene expression, hypothalamus gonadotrophin-releasing hormone neuron development, innate immune response, ion transmembrane transport, mRNA metabolic process, male meiosis I, mitotic anaphase, mitotic cell cycle, negative regulation of apoptotic process, negative regulation of epidermal growth factor receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transforming growth factor beta receptor signaling pathway, negative regulation of type I interferon production, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, neurotrophin TRK receptor signaling pathway, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, nucleotide-binding oligomerization domain containing signaling pathway, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, positive regulation of type I interferon production, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, regulation of apoptotic process, regulation of transcription from RNA polymerase II promoter in response to hypoxia, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, seminiferous tubule development, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, transmembrane transport, ubiquitin homeostasis, viral protein processing, viral reproduction, viral reproductive process, virion assembly cytosol, endocytic vesicle membrane, endosome membrane, nucleoplasm protein binding Human UniProtKB:Q68DV7 UBC ENSEMBL UniProtKB {GO:0005515=PMID:19285159, GO:0002474=Reactome:REACT_75820, GO:0010467=Reactome:REACT_71, GO:0010992=GO_REF:0000019, GO:0007220=Reactome:REACT_2001, GO:0006367=Reactome:REACT_12627, GO:0019221=Reactome:REACT_25229, GO:0007249=Reactome:REACT_25351, GO:0002020=PMID:21185309, GO:0051403=Reactome:REACT_21308, GO:0002756=Reactome:REACT_6809, GO:0034220=Reactome:REACT_25300, GO:0007219=Reactome:REACT_118859, GO:0007173=Reactome:REACT_9417, GO:0002755=Reactome:REACT_27215, GO:0007179=Reactome:REACT_120850, GO:0043123=Reactome:REACT_24918, GO:0006977=Reactome:REACT_1625, GO:0000209=Reactome:REACT_75842, GO:0038124=Reactome:REACT_8006, GO:0038123=Reactome:REACT_8005, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0034134=Reactome:REACT_7980, GO:0042059=Reactome:REACT_12484, GO:0033554=Reactome:REACT_120956, GO:0000122=Reactome:REACT_121111, GO:0019068=Reactome:REACT_6818, GO:0002224=Reactome:REACT_9020, GO:0046788=Reactome:REACT_115893, GO:0007144=GO_REF:0000019, GO:0006281=Reactome:REACT_216, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0021888=GO_REF:0000019, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_121374, GO:0034166=Reactome:REACT_9027, GO:0035666=Reactome:REACT_25281, GO:0000278=Reactome:REACT_152, GO:0010008=Reactome:REACT_115855, GO:0007141=GO_REF:0000019, GO:0016044=Reactome:REACT_11123, GO:0034162=Reactome:REACT_9047, GO:0050852=Reactome:REACT_12526, GO:0022415=Reactome:REACT_6361, GO:0034142=Reactome:REACT_6894, GO:0070423=Reactome:REACT_75776, GO:0061418=Reactome:REACT_120815, GO:0031145=Reactome:REACT_6871, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_75871, GO:0000084=Reactome:REACT_899, GO:0000187=Reactome:REACT_21399, GO:0000082=Reactome:REACT_1783, GO:0051092=Reactome:REACT_21281, GO:0045944=Reactome:REACT_120734, GO:0000087=Reactome:REACT_910, GO:0016197=Reactome:REACT_27258, GO:0016032=Reactome:REACT_6256, GO:0032481=Reactome:REACT_147841, GO:0000080=Reactome:REACT_1590, GO:0032480=Reactome:REACT_25271, GO:0034138=Reactome:REACT_6783, GO:0030512=Reactome:REACT_120727, GO:0048011=Reactome:REACT_13776, GO:0043066=Reactome:REACT_13537, GO:0019082=Reactome:REACT_115860, GO:0051437=Reactome:REACT_6821, GO:0042590=Reactome:REACT_111119, GO:0007254=Reactome:REACT_21368, GO:0071456=Reactome:REACT_121311, GO:0006915=Reactome:REACT_13643, GO:0042981=Reactome:REACT_13648, GO:0051436=Reactome:REACT_6785, GO:0097190=Reactome:REACT_13720, GO:0055085=Reactome:REACT_15518, GO:0051439=Reactome:REACT_6837, GO:0006351=Reactome:REACT_121061, GO:0097009=GO_REF:0000019, GO:0030666=Reactome:REACT_27184, GO:0008585=GO_REF:0000019, GO:0072520=GO_REF:0000019, GO:0002479=Reactome:REACT_111178, GO:0060613=GO_REF:0000019, GO:0034146=Reactome:REACT_9061, GO:0000090=Reactome:REACT_1275} Q96C32 Polyubiquitin-C protein 20130413 {GO:0005515=IPI, GO:0002474=TAS, GO:0010467=TAS, GO:0010992=IEA, GO:0007220=TAS, GO:0006367=TAS, GO:0019221=TAS, GO:0007249=TAS, GO:0002020=IPI, GO:0051403=TAS, GO:0002756=TAS, GO:0034220=TAS, GO:0007219=TAS, GO:0007173=TAS, GO:0002755=TAS, GO:0007179=TAS, GO:0043123=TAS, GO:0006977=TAS, GO:0000209=TAS, GO:0038124=TAS, GO:0038123=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0034134=TAS, GO:0042059=TAS, GO:0033554=TAS, GO:0000122=TAS, GO:0019068=TAS, GO:0002224=TAS, GO:0046788=TAS, GO:0007144=IEA, GO:0006281=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0021888=IEA, GO:0000075=TAS, GO:0005654=TAS, GO:0034166=TAS, GO:0035666=TAS, GO:0000278=TAS, GO:0010008=TAS, GO:0007141=IEA, GO:0016044=TAS, GO:0034162=TAS, GO:0050852=TAS, GO:0022415=TAS, GO:0034142=TAS, GO:0070423=TAS, GO:0061418=TAS, GO:0031145=TAS, GO:0035872=TAS, GO:0005829=TAS, GO:0000084=TAS, GO:0000187=TAS, GO:0000082=TAS, GO:0051092=TAS, GO:0045944=TAS, GO:0000087=TAS, GO:0016197=TAS, GO:0016032=TAS, GO:0032481=TAS, GO:0000080=TAS, GO:0032480=TAS, GO:0034138=TAS, GO:0030512=TAS, GO:0048011=TAS, GO:0043066=TAS, GO:0019082=TAS, GO:0051437=TAS, GO:0042590=TAS, GO:0007254=TAS, GO:0071456=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0051436=TAS, GO:0097190=TAS, GO:0055085=TAS, GO:0051439=TAS, GO:0006351=TAS, GO:0097009=IEA, GO:0030666=TAS, GO:0008585=IEA, GO:0072520=IEA, GO:0002479=TAS, GO:0060613=IEA, GO:0034146=TAS, GO:0000090=TAS} DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, DNA repair, G1 phase of mitotic cell cycle, G1/S transition of mitotic cell cycle, I-kappaB kinase/NF-kappaB cascade, JNK cascade, M phase of mitotic cell cycle, MyD88-dependent toll-like receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, Notch receptor processing, Notch signaling pathway, RNA metabolic process, S phase of mitotic cell cycle, T cell receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, activation of MAPK activity, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, apoptotic signaling pathway, cell cycle checkpoint, cellular membrane organization, cellular response to hypoxia, cellular response to stress, cytokine-mediated signaling pathway, egress of virus within host cell, endosomal transport, energy homeostasis, epidermal growth factor receptor signaling pathway, fat pad development, female gonad development, female meiosis I, fibroblast growth factor receptor signaling pathway, gene expression, hypothalamus gonadotrophin-releasing hormone neuron development, innate immune response, ion transmembrane transport, mRNA metabolic process, male meiosis I, mitotic anaphase, mitotic cell cycle, negative regulation of apoptotic process, negative regulation of epidermal growth factor receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transforming growth factor beta receptor signaling pathway, negative regulation of type I interferon production, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, neurotrophin TRK receptor signaling pathway, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, nucleotide-binding oligomerization domain containing signaling pathway, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, positive regulation of type I interferon production, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein polyubiquitination, regulation of apoptotic process, regulation of transcription from RNA polymerase II promoter in response to hypoxia, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, seminiferous tubule development, stress-activated MAPK cascade, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, transmembrane transport, ubiquitin homeostasis, viral protein processing, viral reproduction, viral reproductive process, virion assembly cytosol, endocytic vesicle membrane, endosome membrane, nucleoplasm protease binding, protein binding Human Ensembl:ENSMUSP00000114180 UBD UniProtKB UniProtKB {GO:0005515=PMID:19033385, GO:0006511=PMID:17889673, GO:0016567=PMID:17889673, GO:0043065=PMID:16495380, GO:0016235=PMID:19033385, GO:0035417=PMID:16495226, GO:0010243=GO_REF:0000019, GO:0032446=PMID:9368598, GO:0005634=PMID:12730673, GO:0005737=GO_REF:0000024, GO:0070842=PMID:19033385, GO:0006508=PMID:9368598, GO:0070628=PMID:16707496, GO:0034612=PMID:17889673, GO:0043011=PMID:19028597, GO:0034341=PMID:17889673, GO:0043123=PMID:19959714} O15205 Ubiquitin D protein 20100326 {GO:0005515=IPI, GO:0006511=IDA, GO:0016567=IDA, GO:0043065=IMP, GO:0016235=IDA, GO:0035417=IMP, GO:0010243=IEA, GO:0032446=NAS, GO:0005634=IDA, GO:0005737=ISS, GO:0070842=IDA, GO:0006508=NAS, GO:0070628=IDA, GO:0034612=IEP, GO:0043011=IMP, GO:0034341=IEP, GO:0043123=IMP} aggresome assembly, myeloid dendritic cell differentiation, negative regulation of mitotic prometaphase, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of apoptotic process, protein modification by small protein conjugation, protein ubiquitination, proteolysis, response to interferon-gamma, response to organic nitrogen, response to tumor necrosis factor, ubiquitin-dependent protein catabolic process aggresome, cytoplasm, nucleus proteasome binding, protein binding Human UniProtKB:P63072 UBE2A Reactome UniProtKB {GO:0000209=Reactome:REACT_75842, GO:0005515=PMID:21329877, GO:0001741=GO_REF:0000019, GO:0002474=Reactome:REACT_75820, GO:0006511=PMID:1559696, GO:0000790=GO_REF:0000019, GO:0004842=PMID:20061386, GO:0008284=PMID:11953320, GO:0033522=PMID:11953320, GO:0033503=PMID:19410543, GO:0060135=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0001701=GO_REF:0000019, GO:0006301=PMID:1559696, GO:0005829=Reactome:REACT_75901, GO:0051865=PMID:11953320, GO:0006281=PMID:1717990, GO:0070979=PMID:20061386, GO:0070936=PMID:20061386, GO:0009411=PMID:1717990, GO:0000785=GO_REF:0000024, GO:0031625=PMID:10908344} P49459 Ubiquitin-conjugating enzyme E2 A protein 20101011 {GO:0000209=TAS, GO:0005515=IPI, GO:0001741=IEA, GO:0002474=TAS, GO:0006511=NAS, GO:0000790=IEA, GO:0004842=IDA, GO:0008284=IDA, GO:0033522=IDA, GO:0033503=IDA, GO:0060135=IEA, GO:0005524=IEA, GO:0001701=IEA, GO:0006301=NAS, GO:0005829=TAS, GO:0051865=IDA, GO:0006281=IGI, GO:0070979=IDA, GO:0070936=IDA, GO:0009411=IGI, GO:0000785=ISS, GO:0031625=IPI} DNA repair, antigen processing and presentation of peptide antigen via MHC class I, histone H2A ubiquitination, in utero embryonic development, maternal process involved in female pregnancy, positive regulation of cell proliferation, postreplication repair, protein K11-linked ubiquitination, protein K48-linked ubiquitination, protein autoubiquitination, protein polyubiquitination, response to UV, ubiquitin-dependent protein catabolic process HULC complex, XY body, chromatin, cytosol, nuclear chromatin ATP binding, protein binding, ubiquitin protein ligase binding, ubiquitin-protein ligase activity Human UBE2B UniProtKB UniProtKB {GO:0005515=PMID:12776193, GO:0006344=GO_REF:0000019, GO:0006511=PMID:1559696, GO:0000790=GO_REF:0000019, GO:0004842=PMID:10373550, GO:0006513=PMID:18339854, GO:0016567=PMID:10373550, GO:0033522=PMID:18339854, GO:0005886=GO_REF:0000039, GO:0033503=PMID:19410543, GO:0007288=GO_REF:0000019, GO:0005657=PMID:18363965, GO:0005634=PMID:18339854, GO:0007283=PMID:18497339, GO:0006301=PMID:1559696, GO:0070534=PMID:20061386, GO:0005737=PMID:18339854, GO:0070193=GO_REF:0000019, GO:0060070=GO_REF:0000024, GO:0000785=GO_REF:0000024, GO:0009411=PMID:1717990, GO:0043951=PMID:10373550, GO:0031625=PMID:18363965, GO:0000209=PMID:18339854, GO:0001741=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0032869=GO_REF:0000019, GO:0016881=GO_REF:0000002, GO:0042493=PMID:14981545, GO:0010845=GO_REF:0000019, GO:0070076=GO_REF:0000019, GO:0050821=PMID:18339854, GO:0001701=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0006974=PMID:14981545, GO:0051865=PMID:19123975, GO:0033128=GO_REF:0000019, GO:0006281=PMID:1717990, GO:0070979=PMID:20061386, GO:0051026=GO_REF:0000019, GO:0043161=PMID:10373550, GO:0070936=PMID:20061386} P63146 Ubiquitin-conjugating enzyme E2 B protein 20120425 {GO:0005515=IPI, GO:0006344=IEA, GO:0006511=NAS, GO:0000790=IEA, GO:0004842=IDA, GO:0006513=IMP, GO:0016567=IDA, GO:0033522=IMP, GO:0005886=IEA, GO:0033503=IDA, GO:0007288=IEA, GO:0005657=IDA, GO:0005634=IDA, GO:0007283=TAS, GO:0006301=NAS, GO:0070534=IDA, GO:0005737=IDA, GO:0070193=IEA, GO:0060070=ISS, GO:0000785=ISS, GO:0009411=IGI, GO:0043951=IDA, GO:0031625=IPI, GO:0000209=IMP, GO:0001741=IEA, GO:0001666=IEA, GO:0043066=IEA, GO:0032869=IEA, GO:0016881=IEA, GO:0042493=IDA, GO:0010845=IEA, GO:0070076=IEA, GO:0050821=IMP, GO:0001701=IEA, GO:0005524=IEA, GO:0006974=IDA, GO:0051865=IDA, GO:0033128=IEA, GO:0006281=IGI, GO:0070979=IDA, GO:0051026=IEA, GO:0043161=IDA, GO:0070936=IDA} DNA repair, canonical Wnt receptor signaling pathway, cellular response to insulin stimulus, chiasma assembly, histone H2A ubiquitination, histone lysine demethylation, in utero embryonic development, maintenance of chromatin silencing, negative regulation of apoptotic process, negative regulation of cAMP-mediated signaling, negative regulation of histone phosphorylation, positive regulation of reciprocal meiotic recombination, postreplication repair, proteasomal ubiquitin-dependent protein catabolic process, protein K11-linked ubiquitination, protein K48-linked ubiquitination, protein K63-linked ubiquitination, protein autoubiquitination, protein monoubiquitination, protein polyubiquitination, protein stabilization, protein ubiquitination, response to DNA damage stimulus, response to UV, response to drug, response to hypoxia, sperm axoneme assembly, spermatogenesis, synaptonemal complex organization, ubiquitin-dependent protein catabolic process HULC complex, XY body, chromatin, cytoplasm, nuclear chromatin, nucleus, plasma membrane, replication fork ATP binding, acid-amino acid ligase activity, protein binding, ubiquitin protein ligase binding, ubiquitin-protein ligase activity Human UBE2C Reactome UniProtKB {GO:0010994=PMID:19822757, GO:0005515=PMID:19822757, GO:0006511=PMID:18485873, GO:0007094=Reactome:REACT_2137, GO:0004842=PMID:20061386, GO:0016567=PMID:9122200, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_9035, GO:0051488=PMID:17443180, GO:0008054=PMID:9122200, GO:0005680=PMID:19822757, GO:0000087=Reactome:REACT_910, GO:0007051=PMID:15504738, GO:0010458=PMID:19822757, GO:0048015=PMID:15504738, GO:0051437=Reactome:REACT_6904, GO:0031536=PMID:9122200, GO:0051436=Reactome:REACT_6785, GO:0005524=GO_REF:0000037, GO:0051439=Reactome:REACT_6867, GO:0007049=PMID:15504738, GO:0070979=PMID:20061386, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9051, GO:0070936=PMID:20061386, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} O00762 Ubiquitin-conjugating enzyme E2 C protein 20130301 {GO:0010994=IDA, GO:0005515=IPI, GO:0006511=IDA, GO:0007094=TAS, GO:0004842=IDA, GO:0016567=IDA, GO:0031145=TAS, GO:0005829=TAS, GO:0051488=TAS, GO:0008054=IDA, GO:0005680=IDA, GO:0000087=TAS, GO:0007051=NAS, GO:0010458=IMP, GO:0048015=NAS, GO:0051437=TAS, GO:0031536=IMP, GO:0051436=TAS, GO:0005524=IEA, GO:0051439=TAS, GO:0007049=NAS, GO:0070979=IDA, GO:0000075=TAS, GO:0005654=TAS, GO:0070936=IDA, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, activation of anaphase-promoting complex activity, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle, cell cycle checkpoint, cell division, cyclin catabolic process, exit from mitosis, free ubiquitin chain polymerization, mitotic anaphase, mitotic cell cycle, mitotic spindle assembly checkpoint, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, phosphatidylinositol-mediated signaling, positive regulation of exit from mitosis, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K11-linked ubiquitination, protein K48-linked ubiquitination, protein ubiquitination, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, spindle organization, ubiquitin-dependent protein catabolic process anaphase-promoting complex, cytosol, nucleoplasm ATP binding, protein binding, ubiquitin-protein ligase activity Human UBE2D1 IntAct UniProtKB {GO:0005515=PMID:19690564, GO:0006511=PMID:16275645, GO:0007094=Reactome:REACT_2137, GO:0010467=Reactome:REACT_71, GO:0004842=PMID:18359941, GO:0034142=Reactome:REACT_6894, GO:0006367=Reactome:REACT_12627, GO:0061418=Reactome:REACT_120815, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_120954, GO:0002756=Reactome:REACT_6809, GO:0005737=PMID:18845142, GO:0000087=Reactome:REACT_910, GO:0031398=PMID:16275645, GO:0007179=Reactome:REACT_6844, GO:0034138=Reactome:REACT_6783, GO:0000209=PMID:16275645, GO:0051437=Reactome:REACT_6904, GO:0071456=Reactome:REACT_121311, GO:0033554=Reactome:REACT_120956, GO:0051436=Reactome:REACT_6785, GO:0000122=Reactome:REACT_121111, GO:0030509=Reactome:REACT_12034, GO:0002224=Reactome:REACT_6966, GO:0005524=GO_REF:0000037, GO:0051439=Reactome:REACT_6867, GO:0006351=Reactome:REACT_121061, GO:0045087=Reactome:REACT_6802, GO:0000075=Reactome:REACT_1538, GO:0035666=Reactome:REACT_25281, GO:0005654=Reactome:REACT_121374, GO:0000278=Reactome:REACT_152, GO:0070936=PMID:20061386, GO:0000090=Reactome:REACT_1275} P51668 Ubiquitin-conjugating enzyme E2 D1 protein 20130415 {GO:0005515=IPI, GO:0006511=IDA, GO:0007094=TAS, GO:0010467=TAS, GO:0004842=IDA, GO:0034142=TAS, GO:0006367=TAS, GO:0061418=TAS, GO:0031145=TAS, GO:0005829=TAS, GO:0002756=TAS, GO:0005737=IDA, GO:0000087=TAS, GO:0031398=IDA, GO:0007179=TAS, GO:0034138=TAS, GO:0000209=IDA, GO:0051437=TAS, GO:0071456=TAS, GO:0033554=TAS, GO:0051436=TAS, GO:0000122=TAS, GO:0030509=TAS, GO:0002224=TAS, GO:0005524=IEA, GO:0051439=TAS, GO:0006351=TAS, GO:0045087=TAS, GO:0000075=TAS, GO:0035666=TAS, GO:0005654=TAS, GO:0000278=TAS, GO:0070936=IDA, GO:0000090=TAS} BMP signaling pathway, M phase of mitotic cell cycle, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle checkpoint, cellular response to hypoxia, cellular response to stress, gene expression, innate immune response, mitotic anaphase, mitotic cell cycle, mitotic spindle assembly checkpoint, negative regulation of transcription from RNA polymerase II promoter, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of protein ubiquitination, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K48-linked ubiquitination, protein polyubiquitination, regulation of transcription from RNA polymerase II promoter in response to hypoxia, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor signaling pathway, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, ubiquitin-dependent protein catabolic process cytoplasm, cytosol, nucleoplasm ATP binding, protein binding, ubiquitin-protein ligase activity Human UniProtKB:Q9Y3C5 UBE2D2 BHF-UCL UniProtKB {GO:0005515=PMID:20705607, GO:0006511=PMID:7724550, GO:0004842=PMID:18703417, GO:0016567=PMID:9990509, GO:0034142=Reactome:REACT_6894, GO:0016881=GO_REF:0000002, GO:0071456=Reactome:REACT_121311, GO:0061418=Reactome:REACT_120815, GO:0033554=Reactome:REACT_120956, GO:0002224=Reactome:REACT_6966, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_120954, GO:0002756=Reactome:REACT_6809, GO:0045087=Reactome:REACT_6802, GO:0035666=Reactome:REACT_25281, GO:0005654=Reactome:REACT_121374, GO:0070936=PMID:20061386, GO:0034138=Reactome:REACT_6783, GO:0006464=PMID:8090726} P62837 Ubiquitin-conjugating enzyme E2 D2 protein 20081003 {GO:0005515=IPI, GO:0006511=TAS, GO:0004842=IDA, GO:0016567=IDA, GO:0034142=TAS, GO:0016881=IEA, GO:0071456=TAS, GO:0061418=TAS, GO:0033554=TAS, GO:0002224=TAS, GO:0005524=IEA, GO:0005829=TAS, GO:0002756=TAS, GO:0045087=TAS, GO:0035666=TAS, GO:0005654=TAS, GO:0070936=IDA, GO:0034138=TAS, GO:0006464=TAS} MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, cellular protein modification process, cellular response to hypoxia, cellular response to stress, innate immune response, protein K48-linked ubiquitination, protein ubiquitination, regulation of transcription from RNA polymerase II promoter in response to hypoxia, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor signaling pathway, ubiquitin-dependent protein catabolic process cytosol, nucleoplasm ATP binding, acid-amino acid ligase activity, protein binding, ubiquitin-protein ligase activity Human UBE2D3 BHF-UCL UniProtKB {GO:0005515=PMID:19690564, GO:0006511=PMID:8530467, GO:0010467=Reactome:REACT_71, GO:0004842=PMID:20347421, GO:0034142=Reactome:REACT_6894, GO:0006513=PMID:20347421, GO:0016567=PMID:9990509, GO:0006367=Reactome:REACT_12627, GO:0005886=GO_REF:0000039, GO:0061418=Reactome:REACT_120815, GO:0005829=Reactome:REACT_120954, GO:0002756=Reactome:REACT_6809, GO:0007179=Reactome:REACT_6844, GO:0034138=Reactome:REACT_6783, GO:0032480=Reactome:REACT_25271, GO:0000209=PMID:14765125, GO:0016881=GO_REF:0000002, GO:0071456=Reactome:REACT_121311, GO:0006915=GO_REF:0000037, GO:0033554=Reactome:REACT_120956, GO:0000122=Reactome:REACT_121111, GO:0030509=Reactome:REACT_12034, GO:0002224=Reactome:REACT_6966, GO:0005524=GO_REF:0000037, GO:0006351=Reactome:REACT_121061, GO:0006281=GO_REF:0000037, GO:0070979=PMID:20061386, GO:0045087=Reactome:REACT_6802, GO:0035666=Reactome:REACT_25281, GO:0043161=PMID:20347421, GO:0005654=Reactome:REACT_121374, GO:0070936=PMID:20061386, GO:0010008=GO_REF:0000039, GO:0006464=PMID:8090726} P61077 Ubiquitin-conjugating enzyme E2 D3 protein 20081003 {GO:0005515=IPI, GO:0006511=TAS, GO:0010467=TAS, GO:0004842=IDA, GO:0034142=TAS, GO:0006513=IDA, GO:0016567=IDA, GO:0006367=TAS, GO:0005886=IEA, GO:0061418=TAS, GO:0005829=TAS, GO:0002756=TAS, GO:0007179=TAS, GO:0034138=TAS, GO:0032480=TAS, GO:0000209=IDA, GO:0016881=IEA, GO:0071456=TAS, GO:0006915=IEA, GO:0033554=TAS, GO:0000122=TAS, GO:0030509=TAS, GO:0002224=TAS, GO:0005524=IEA, GO:0006351=TAS, GO:0006281=IEA, GO:0070979=IDA, GO:0045087=TAS, GO:0035666=TAS, GO:0043161=IDA, GO:0005654=TAS, GO:0070936=IDA, GO:0010008=IEA, GO:0006464=TAS} BMP signaling pathway, DNA repair, MyD88-independent toll-like receptor signaling pathway, TRIF-dependent toll-like receptor signaling pathway, apoptotic process, cellular protein modification process, cellular response to hypoxia, cellular response to stress, gene expression, innate immune response, negative regulation of transcription from RNA polymerase II promoter, negative regulation of type I interferon production, proteasomal ubiquitin-dependent protein catabolic process, protein K11-linked ubiquitination, protein K48-linked ubiquitination, protein monoubiquitination, protein polyubiquitination, protein ubiquitination, regulation of transcription from RNA polymerase II promoter in response to hypoxia, toll-like receptor 3 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor signaling pathway, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, ubiquitin-dependent protein catabolic process cytosol, endosome membrane, nucleoplasm, plasma membrane ATP binding, acid-amino acid ligase activity, protein binding, ubiquitin-protein ligase activity Human UBE2D4 IntAct UniProtKB {GO:0005515=PMID:19690564, GO:0035519=PMID:20061386, GO:0085020=PMID:20061386, GO:0004842=PMID:20061386, GO:0070534=PMID:20061386, GO:0070979=PMID:20061386, GO:0016881=GO_REF:0000002, GO:0070936=PMID:20061386, GO:0044314=PMID:20061386, GO:0005524=GO_REF:0000037} Q9Y2X8 Ubiquitin-conjugating enzyme E2 D4 protein 20130415 {GO:0005515=IPI, GO:0035519=IDA, GO:0085020=IDA, GO:0004842=IDA, GO:0070534=IDA, GO:0070979=IDA, GO:0016881=IEA, GO:0070936=IDA, GO:0044314=IDA, GO:0005524=IEA} protein K11-linked ubiquitination, protein K27-linked ubiquitination, protein K29-linked ubiquitination, protein K48-linked ubiquitination, protein K6-linked ubiquitination, protein K63-linked ubiquitination ATP binding, acid-amino acid ligase activity, protein binding, ubiquitin-protein ligase activity Human UniProtKB:Q8ND25 UBE2E1 BHF-UCL UniProtKB {GO:0005515=PMID:19690564, GO:0006511=PMID:8576257, GO:0007094=Reactome:REACT_2137, GO:0004842=PMID:16522193, GO:0016567=PMID:9990509, GO:0033523=PMID:16307923, GO:0019221=Reactome:REACT_25229, GO:0000151=PMID:16307923, GO:0005634=PMID:18845142, GO:0031145=Reactome:REACT_6871, GO:0005829=Reactome:REACT_115890, GO:0000087=Reactome:REACT_910, GO:0042296=PMID:16428300, GO:0000209=PMID:16522193, GO:0016881=GO_REF:0000002, GO:0032020=PMID:16428300, GO:0051437=Reactome:REACT_6904, GO:0051436=Reactome:REACT_6785, GO:0005524=GO_REF:0000037, GO:0051439=Reactome:REACT_6867, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9051, GO:0070936=PMID:20061386, GO:0000278=Reactome:REACT_152, GO:0010390=PMID:16307923, GO:0000090=Reactome:REACT_1275} P51965 Ubiquitin-conjugating enzyme E2 E1 protein 20081003 {GO:0005515=IPI, GO:0006511=TAS, GO:0007094=TAS, GO:0004842=IDA, GO:0016567=IDA, GO:0033523=IDA, GO:0019221=TAS, GO:0000151=IDA, GO:0005634=IDA, GO:0031145=TAS, GO:0005829=TAS, GO:0000087=TAS, GO:0042296=IDA, GO:0000209=IDA, GO:0016881=IEA, GO:0032020=IDA, GO:0051437=TAS, GO:0051436=TAS, GO:0005524=IEA, GO:0051439=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0070936=IDA, GO:0000278=TAS, GO:0010390=IDA, GO:0000090=TAS} ISG15-protein conjugation, M phase of mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell cycle checkpoint, cytokine-mediated signaling pathway, histone H2B ubiquitination, histone monoubiquitination, mitotic anaphase, mitotic cell cycle, mitotic spindle assembly checkpoint, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, protein K48-linked ubiquitination, protein polyubiquitination, protein ubiquitination, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, ubiquitin-dependent protein catabolic process cytosol, nucleoplasm, nucleus, ubiquitin ligase complex ATP binding, ISG15 ligase activity, acid-amino acid ligase activity, protein binding, ubiquitin-protein ligase activity Human UBE2E2 HGNC UniProtKB {GO:0004842=PMID:20061386, GO:0070534=PMID:20061386, GO:0070979=PMID:20061386, GO:0016881=GO_REF:0000002, GO:0032020=PMID:16428300, GO:0070936=PMID:20061386, GO:0005524=GO_REF:0000037, GO:0042296=PMID:16428300} Q96LR5 Ubiquitin-conjugating enzyme E2 E2 protein 20070205 {GO:0004842=IDA, GO:0070534=IDA, GO:0070979=IDA, GO:0016881=IEA, GO:0032020=IDA, GO:0070936=IDA, GO:0005524=IEA, GO:0042296=IDA} ISG15-protein conjugation, protein K11-linked ubiquitination, protein K48-linked ubiquitination, protein K63-linked ubiquitination ATP binding, ISG15 ligase activity, acid-amino acid ligase activity, ubiquitin-protein ligase activity Human UBE2E3 UniProtKB UniProtKB {GO:0004842=PMID:20061386, GO:0070534=PMID:20061386, GO:0005737=GO_REF:0000039, GO:0070979=PMID:20061386, GO:0005634=GO_REF:0000039, GO:0070936=PMID:20061386, GO:0005524=GO_REF:0000037, GO:0040008=GO_REF:0000037} Q969T4 Ubiquitin-conjugating enzyme E2 E3 protein 20100719 {GO:0004842=IDA, GO:0070534=IDA, GO:0005737=IEA, GO:0070979=IDA, GO:0005634=IEA, GO:0070936=IDA, GO:0005524=IEA, GO:0040008=IEA} protein K11-linked ubiquitination, protein K48-linked ubiquitination, protein K63-linked ubiquitination, regulation of growth cytoplasm, nucleus ATP binding, ubiquitin-protein ligase activity Human UBE2F UniProtKB UniProtKB {GO:0005515=PMID:19250909, GO:0016881=GO_REF:0000002, GO:0019788=PMID:19250909, GO:0045116=PMID:19250909, GO:0005524=GO_REF:0000037} Q969M7 NEDD8-conjugating enzyme UBE2F protein 20090422 {GO:0005515=IPI, GO:0016881=IEA, GO:0019788=IDA, GO:0045116=IDA, GO:0005524=IEA} protein neddylation ATP binding, NEDD8 ligase activity, acid-amino acid ligase activity, protein binding Human UBE2G1 PINC UniProtKB {GO:0006511=PMID:8893823, GO:0004842=PMID:20061386, GO:0070534=PMID:20061386, GO:0016881=GO_REF:0000002, GO:0070936=PMID:20061386, GO:0005524=GO_REF:0000037, GO:0031625=PMID:15673284} P62253 Ubiquitin-conjugating enzyme E2 G1 protein 20061130 {GO:0006511=TAS, GO:0004842=IDA, GO:0070534=IDA, GO:0016881=IEA, GO:0070936=IDA, GO:0005524=IEA, GO:0031625=IPI} protein K48-linked ubiquitination, protein K63-linked ubiquitination, ubiquitin-dependent protein catabolic process ATP binding, acid-amino acid ligase activity, ubiquitin protein ligase binding, ubiquitin-protein ligase activity Human UBE2G2 PINC UniProtKB {GO:0005515=PMID:17681147, GO:0006511=PMID:9693041, GO:0004842=PMID:20061386, GO:0016881=GO_REF:0000002, GO:0005783=GO_REF:0000019, GO:0030433=PMID:22607976, GO:0070936=PMID:20061386, GO:0005524=GO_REF:0000037, GO:0018279=PMID:22607976, GO:0005829=PMID:16780588} P60604 Ubiquitin-conjugating enzyme E2 G2 protein 20061116 {GO:0005515=IPI, GO:0006511=TAS, GO:0004842=IDA, GO:0016881=IEA, GO:0005783=IEA, GO:0030433=IMP, GO:0070936=IDA, GO:0005524=IEA, GO:0018279=IMP, GO:0005829=IDA} ER-associated protein catabolic process, protein K48-linked ubiquitination, protein N-linked glycosylation via asparagine, ubiquitin-dependent protein catabolic process cytosol, endoplasmic reticulum ATP binding, acid-amino acid ligase activity, protein binding, ubiquitin-protein ligase activity Human UBE2H IntAct UniProtKB {GO:0005515=PMID:20864041, GO:0006511=PMID:8132613, GO:0004842=PMID:20061386, GO:0070979=PMID:20061386, GO:0016881=GO_REF:0000002, GO:0070936=PMID:20061386, GO:0005524=GO_REF:0000037} P62256 Ubiquitin-conjugating enzyme E2 H protein 20130415 {GO:0005515=IPI, GO:0006511=TAS, GO:0004842=IDA, GO:0070979=IDA, GO:0016881=IEA, GO:0070936=IDA, GO:0005524=IEA} protein K11-linked ubiquitination, protein K48-linked ubiquitination, ubiquitin-dependent protein catabolic process ATP binding, acid-amino acid ligase activity, protein binding, ubiquitin-protein ligase activity Human UniProtKB:Q9UBF1 UBE2I BHF-UCL UniProtKB {GO:0005515=PMID:19955185, GO:0006511=PMID:8565643, GO:0004842=PMID:19955185, GO:0010469=GO_REF:0000019, GO:0045202=GO_REF:0000019, GO:0005634=PMID:16631117, GO:0030425=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0051091=GO_REF:0000019, GO:0007059=GO_REF:0000037, GO:0043398=GO_REF:0000019, GO:0019789=PMID:19955185, GO:0071535=PMID:19407830, GO:0000795=PMID:8610150, GO:0016925=PMID:19955185, GO:0043425=GO_REF:0000019, GO:0000122=PMID:19955185, GO:0008022=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0016604=GO_REF:0000019, GO:0007067=GO_REF:0000037, GO:0019048=GO_REF:0000037, GO:0016605=PMID:9885291, GO:0033145=GO_REF:0000019, GO:0001650=GO_REF:0000019, GO:0043161=GO_REF:0000019, GO:0019899=PMID:17087506, GO:0045892=PMID:16631117, GO:0006464=PMID:8798754, GO:0051301=GO_REF:0000037, GO:0008134=PMID:19744555} P63279 SUMO-conjugating enzyme UBC9 protein 20120708 {GO:0005515=IPI, GO:0006511=TAS, GO:0004842=TAS, GO:0010469=IEA, GO:0045202=IEA, GO:0005634=IDA, GO:0030425=IEA, GO:0005737=IEA, GO:0051091=IEA, GO:0007059=IEA, GO:0043398=IEA, GO:0019789=IDA, GO:0071535=IPI, GO:0000795=TAS, GO:0016925=IDA, GO:0043425=IEA, GO:0000122=IMP, GO:0008022=IEA, GO:0005524=IEA, GO:0016604=IEA, GO:0007067=IEA, GO:0019048=IEA, GO:0016605=IDA, GO:0033145=IEA, GO:0001650=IEA, GO:0043161=IEA, GO:0019899=IPI, GO:0045892=IDA, GO:0006464=TAS, GO:0051301=IEA, GO:0008134=IPI} cell division, cellular protein modification process, chromosome segregation, mitosis, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of intracellular steroid hormone receptor signaling pathway, positive regulation of sequence-specific DNA binding transcription factor activity, proteasomal ubiquitin-dependent protein catabolic process, protein sumoylation, regulation of receptor activity, ubiquitin-dependent protein catabolic process, virus-host interaction PML body, cytoplasm, dendrite, fibrillar center, nuclear body, nucleus, synapse, synaptonemal complex ATP binding, HLH domain binding, RING-like zinc finger domain binding, SUMO ligase activity, bHLH transcription factor binding, enzyme binding, protein C-terminus binding, protein binding, transcription factor binding, ubiquitin-protein ligase activity Human UniProtKB:Q07869 UBE2J1 UniProtKB UniProtKB {GO:0004842=GO_REF:0000003, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0030433=PMID:22607976, GO:0005524=GO_REF:0000037, GO:0018279=PMID:22607976} Q9Y385 Ubiquitin-conjugating enzyme E2 J1 protein 20120920 {GO:0004842=IEA, GO:0005789=IEA, GO:0016021=IEA, GO:0030433=IMP, GO:0005524=IEA, GO:0018279=IMP} ER-associated protein catabolic process, protein N-linked glycosylation via asparagine endoplasmic reticulum membrane, integral to membrane ATP binding, ubiquitin-protein ligase activity Human UBE2J2 UniProtKB UniProtKB {GO:0006986=GO_REF:0000037, GO:0004842=GO_REF:0000003, GO:0016881=GO_REF:0000002, GO:0005783=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0005524=GO_REF:0000037} Q8N2K1 Ubiquitin-conjugating enzyme E2 J2 protein 20130413 {GO:0006986=IEA, GO:0004842=IEA, GO:0016881=IEA, GO:0005783=IEA, GO:0005789=IEA, GO:0016021=IEA, GO:0005524=IEA} response to unfolded protein endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane ATP binding, acid-amino acid ligase activity, ubiquitin-protein ligase activity Human UniProtKB-SubCell:SL-0097 UBE2K PINC UniProtKB {GO:0006511=PMID:8702625, GO:0004842=PMID:20061386, GO:0005737=GO_REF:0000039, GO:0016881=GO_REF:0000002, GO:0034450=PMID:17873885, GO:0070936=PMID:20061386, GO:0005524=GO_REF:0000037, GO:0031625=PMID:17873885} P61086 Ubiquitin-conjugating enzyme E2 K protein 20061115 {GO:0006511=TAS, GO:0004842=IDA, GO:0005737=IEA, GO:0016881=IEA, GO:0034450=IDA, GO:0070936=IDA, GO:0005524=IEA, GO:0031625=IPI} protein K48-linked ubiquitination, ubiquitin-dependent protein catabolic process cytoplasm ATP binding, acid-amino acid ligase activity, ubiquitin protein ligase binding, ubiquitin-protein ligase activity, ubiquitin-ubiquitin ligase activity Human UBE2L3 BHF-UCL UniProtKB {GO:0000209=PMID:10888878, GO:0005515=PMID:9990509, GO:0006511=PMID:8672131, GO:0004842=PMID:10888878, GO:0006355=PMID:15367689, GO:0016567=PMID:9990509, GO:0016881=GO_REF:0000002, GO:0008283=PMID:18946090, GO:0003713=PMID:15367689, GO:0000151=PMID:8563171, GO:0005634=PMID:11278816, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0071385=PMID:17003263, GO:0005737=PMID:9990509, GO:0070979=PMID:20061386, GO:0071383=PMID:15367689, GO:0019899=PMID:8563171, GO:0031625=PMID:21532592, GO:0006464=PMID:8576257} P68036 Ubiquitin-conjugating enzyme E2 L3 protein 20081003 {GO:0000209=IDA, GO:0005515=IPI, GO:0006511=TAS, GO:0004842=IMP, GO:0006355=IMP, GO:0016567=IDA, GO:0016881=IEA, GO:0008283=IMP, GO:0003713=IDA, GO:0000151=TAS, GO:0005634=IDA, GO:0005524=IEA, GO:0006351=IEA, GO:0071385=IDA, GO:0005737=IDA, GO:0070979=IDA, GO:0071383=IMP, GO:0019899=TAS, GO:0031625=IPI, GO:0006464=TAS} cell proliferation, cellular protein modification process, cellular response to glucocorticoid stimulus, cellular response to steroid hormone stimulus, protein K11-linked ubiquitination, protein polyubiquitination, protein ubiquitination, regulation of transcription, DNA-dependent, transcription, DNA-dependent, ubiquitin-dependent protein catabolic process cytoplasm, nucleus, ubiquitin ligase complex ATP binding, acid-amino acid ligase activity, enzyme binding, protein binding, transcription coactivator activity, ubiquitin protein ligase binding, ubiquitin-protein ligase activity Human UBE2L6 IntAct UniProtKB {GO:0005515=PMID:16709802, GO:0004842=GO_REF:0000003, GO:0016881=GO_REF:0000002, GO:0032020=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0019941=GO_REF:0000019, GO:0019221=Reactome:REACT_25229, GO:0032480=Reactome:REACT_25271, GO:0006464=PMID:9153201, GO:0005829=Reactome:REACT_116157, GO:0042296=GO_REF:0000019} O14933 Ubiquitin/ISG15-conjugating enzyme E2 L6 protein 20130415 {GO:0005515=IPI, GO:0004842=IEA, GO:0016881=IEA, GO:0032020=IEA, GO:0045087=TAS, GO:0019941=IEA, GO:0019221=TAS, GO:0032480=TAS, GO:0006464=TAS, GO:0005829=TAS, GO:0042296=IEA} ISG15-protein conjugation, cellular protein modification process, cytokine-mediated signaling pathway, innate immune response, modification-dependent protein catabolic process, negative regulation of type I interferon production cytosol ISG15 ligase activity, acid-amino acid ligase activity, protein binding, ubiquitin-protein ligase activity Human UniProtKB:Q6ZMZ0 UBE2M GOC UniProtKB {GO:0005515=PMID:19549727, GO:0004842=PMID:15694336, GO:0016567=PMID:9694792, GO:0043525=GO_REF:0000019, GO:0016881=GO_REF:0000002, GO:0019788=PMID:19250909, GO:0045116=PMID:19250909, GO:0018169=PMID:15361859, GO:0005575=GO_REF:0000015, GO:0005524=GO_REF:0000037, GO:0006464=PMID:15694336} P61081 NEDD8-conjugating enzyme Ubc12 protein 20130413 {GO:0005515=IPI, GO:0004842=IMP, GO:0016567=TAS, GO:0043525=IEA, GO:0016881=IEA, GO:0019788=IDA, GO:0045116=IDA, GO:0018169=IDA, GO:0005575=ND, GO:0005524=IEA, GO:0006464=IMP} cellular protein modification process, positive regulation of neuron apoptotic process, protein neddylation, protein ubiquitination cellular_component ATP binding, NEDD8 ligase activity, acid-amino acid ligase activity, protein binding, ribosomal S6-glutamic acid ligase activity, ubiquitin-protein ligase activity Human UBE2N IntAct UniProtKB {GO:0005515=PMID:19690564, GO:0050852=Reactome:REACT_12526, GO:0006511=GO_REF:0000019, GO:0043130=PMID:16122702, GO:0004842=PMID:20061386, GO:0034142=Reactome:REACT_6894, GO:0016567=PMID:17349954, GO:0019221=Reactome:REACT_25229, GO:0033182=PMID:17349954, GO:0070423=Reactome:REACT_75776, GO:0000151=PMID:16307917, GO:0005634=PMID:16129784, GO:0035370=PMID:16307917, GO:0045739=PMID:16129784, GO:0035872=Reactome:REACT_75913, GO:0006301=PMID:17349954, GO:0005829=Reactome:REACT_115543, GO:0070534=PMID:20061386, GO:0005737=PMID:16129784, GO:0051092=PMID:16129784, GO:0000724=PMID:17349954, GO:0002755=Reactome:REACT_27215, GO:0006508=PMID:8902611, GO:0051443=PMID:17349954, GO:0043123=Reactome:REACT_24918, GO:0000729=PMID:17349954, GO:0038124=Reactome:REACT_8006, GO:0031372=PMID:16129784, GO:0038123=Reactome:REACT_8005, GO:0016881=GO_REF:0000002, GO:0016574=PMID:17349954, GO:0034134=Reactome:REACT_7980, GO:0031058=PMID:17349954, GO:0002224=Reactome:REACT_9020, GO:0005524=GO_REF:0000037, GO:0006282=PMID:10089880, GO:0045087=Reactome:REACT_6802, GO:0034166=Reactome:REACT_9027, GO:0034146=Reactome:REACT_9061, GO:0034162=Reactome:REACT_9047, GO:0006464=PMID:8902611} P61088 Ubiquitin-conjugating enzyme E2 N protein 20130415 {GO:0005515=IPI, GO:0050852=TAS, GO:0006511=IEA, GO:0043130=IDA, GO:0004842=IDA, GO:0034142=TAS, GO:0016567=IMP, GO:0019221=TAS, GO:0033182=IMP, GO:0070423=TAS, GO:0000151=IDA, GO:0005634=IDA, GO:0035370=IDA, GO:0045739=IMP, GO:0035872=TAS, GO:0006301=IMP, GO:0005829=TAS, GO:0070534=IDA, GO:0005737=TAS, GO:0051092=IMP, GO:0000724=IMP, GO:0002755=TAS, GO:0006508=TAS, GO:0051443=IMP, GO:0043123=TAS, GO:0000729=IMP, GO:0038124=TAS, GO:0031372=IDA, GO:0038123=TAS, GO:0016881=IEA, GO:0016574=IMP, GO:0034134=TAS, GO:0031058=IMP, GO:0002224=TAS, GO:0005524=IEA, GO:0006282=TAS, GO:0045087=TAS, GO:0034166=TAS, GO:0034146=TAS, GO:0034162=TAS, GO:0006464=TAS} DNA double-strand break processing, MyD88-dependent toll-like receptor signaling pathway, T cell receptor signaling pathway, cellular protein modification process, cytokine-mediated signaling pathway, double-strand break repair via homologous recombination, histone ubiquitination, innate immune response, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, nucleotide-binding oligomerization domain containing signaling pathway, positive regulation of DNA repair, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of histone modification, positive regulation of ubiquitin-protein ligase activity, postreplication repair, protein K63-linked ubiquitination, protein ubiquitination, proteolysis, regulation of DNA repair, regulation of histone ubiquitination, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway, ubiquitin-dependent protein catabolic process UBC13-MMS2 complex, UBC13-UEV1A complex, cytoplasm, cytosol, nucleus, ubiquitin ligase complex ATP binding, acid-amino acid ligase activity, protein binding, ubiquitin binding, ubiquitin-protein ligase activity Human UniProtKB:Q9Y3C5 UBE2NL InterPro UniProtKB {GO:0016881=GO_REF:0000002} Q5JXB2 Putative ubiquitin-conjugating enzyme E2 N-like protein 20130413 {GO:0016881=IEA} acid-amino acid ligase activity Human InterPro:IPR000608 UBE2O UniProtKB UniProtKB {GO:0004842=GO_REF:0000003, GO:0016881=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q9C0C9 Ubiquitin-conjugating enzyme E2 O protein 20130413 {GO:0004842=IEA, GO:0016881=IEA, GO:0005524=IEA} ATP binding, acid-amino acid ligase activity, ubiquitin-protein ligase activity Human EC:6.3.2.19 UBE2Q1 IntAct UniProtKB {GO:0005515=PMID:16275660, GO:0004842=GO_REF:0000003, GO:0005524=GO_REF:0000037} Q7Z7E8 Ubiquitin-conjugating enzyme E2 Q1 protein 20130415 {GO:0005515=IPI, GO:0004842=IEA, GO:0005524=IEA} ATP binding, protein binding, ubiquitin-protein ligase activity Human UniProtKB:Q9UNE7 UBE2Q2 UniProtKB UniProtKB {GO:0004842=PMID:20061386, GO:0005737=GO_REF:0000039, GO:0016881=GO_REF:0000002, GO:0070936=PMID:20061386, GO:0005524=GO_REF:0000037} Q8WVN8 Ubiquitin-conjugating enzyme E2 Q2 protein 20100719 {GO:0004842=IDA, GO:0005737=IEA, GO:0016881=IEA, GO:0070936=IDA, GO:0005524=IEA} protein K48-linked ubiquitination cytoplasm ATP binding, acid-amino acid ligase activity, ubiquitin-protein ligase activity Human UBE2R2 UniProtKB UniProtKB {GO:0004842=PMID:20061386, GO:0006513=PMID:20061386, GO:0070936=PMID:20061386, GO:0005524=GO_REF:0000037} Q712K3 Ubiquitin-conjugating enzyme E2 R2 protein 20100719 {GO:0004842=IDA, GO:0006513=IDA, GO:0070936=IDA, GO:0005524=IEA} protein K48-linked ubiquitination, protein monoubiquitination ATP binding, ubiquitin-protein ligase activity Human UBE2S PINC UniProtKB {GO:0010994=PMID:19822757, GO:0035519=PMID:20061386, GO:0010458=PMID:19822757, GO:0085020=PMID:20061386, GO:0004842=PMID:20061386, GO:0016881=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0031145=PMID:19822757, GO:0044314=PMID:20061386, GO:0051488=PMID:19822757, GO:0070534=PMID:20061386, GO:0070979=PMID:20622874, GO:0005680=PMID:19822757, GO:0006464=PMID:1379239, GO:0051301=GO_REF:0000037} Q16763 Ubiquitin-conjugating enzyme E2 S protein 20030904 {GO:0010994=IDA, GO:0035519=IDA, GO:0010458=IMP, GO:0085020=IDA, GO:0004842=IDA, GO:0016881=IEA, GO:0005524=IEA, GO:0031145=IDA, GO:0044314=IDA, GO:0051488=IDA, GO:0070534=IDA, GO:0070979=IDA, GO:0005680=IDA, GO:0006464=TAS, GO:0051301=IEA} activation of anaphase-promoting complex activity, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, cell division, cellular protein modification process, exit from mitosis, free ubiquitin chain polymerization, protein K11-linked ubiquitination, protein K27-linked ubiquitination, protein K29-linked ubiquitination, protein K6-linked ubiquitination, protein K63-linked ubiquitination anaphase-promoting complex ATP binding, acid-amino acid ligase activity, ubiquitin-protein ligase activity Human UBE2T Reactome UniProtKB {GO:0035519=PMID:20061386, GO:0085020=PMID:20061386, GO:0004842=PMID:19111657, GO:0006513=PMID:19111657, GO:0005634=PMID:17938197, GO:0005524=GO_REF:0000037, GO:0044314=PMID:20061386, GO:0006974=PMID:16916645, GO:0051865=PMID:19111657, GO:0070534=PMID:20061386, GO:0006281=Reactome:REACT_216, GO:0070979=PMID:20061386, GO:0003682=PMID:17938197, GO:0005654=Reactome:REACT_18429, GO:0070936=PMID:20061386, GO:0031625=PMID:19111657} Q9NPD8 Ubiquitin-conjugating enzyme E2 T protein 20130301 {GO:0035519=IDA, GO:0085020=IDA, GO:0004842=IDA, GO:0006513=IDA, GO:0005634=TAS, GO:0005524=IEA, GO:0044314=IDA, GO:0006974=IMP, GO:0051865=IDA, GO:0070534=IDA, GO:0006281=TAS, GO:0070979=IDA, GO:0003682=IDA, GO:0005654=TAS, GO:0070936=IDA, GO:0031625=IPI} DNA repair, protein K11-linked ubiquitination, protein K27-linked ubiquitination, protein K29-linked ubiquitination, protein K48-linked ubiquitination, protein K6-linked ubiquitination, protein K63-linked ubiquitination, protein autoubiquitination, protein monoubiquitination, response to DNA damage stimulus nucleoplasm, nucleus ATP binding, chromatin binding, ubiquitin protein ligase binding, ubiquitin-protein ligase activity Human UBE2U UniProtKB UniProtKB {GO:0004842=GO_REF:0000003, GO:0005524=GO_REF:0000037} Q5VVX9 Ubiquitin-conjugating enzyme E2 U protein 20130413 {GO:0004842=IEA, GO:0005524=IEA} ATP binding, ubiquitin-protein ligase activity Human EC:6.3.2.19 UBE2V1 IntAct UniProtKB {GO:0005515=PMID:19549727, GO:0050852=Reactome:REACT_12526, GO:0034142=Reactome:REACT_6894, GO:0070423=Reactome:REACT_75776, GO:0000151=PMID:16307917, GO:0005634=PMID:9305758, GO:0035370=PMID:16307917, GO:0030154=PMID:9418904, GO:0035872=Reactome:REACT_75913, GO:0005829=Reactome:REACT_75924, GO:0005737=PMID:16129784, GO:0070534=PMID:16307917, GO:0051092=PMID:16129784, GO:0002755=Reactome:REACT_27215, GO:0043123=Reactome:REACT_24918, GO:0031371=PMID:16129784, GO:0000209=PMID:10089880, GO:0006355=PMID:9305758, GO:0038124=Reactome:REACT_8006, GO:0016881=GO_REF:0000002, GO:0038123=Reactome:REACT_8005, GO:0034134=Reactome:REACT_7980, GO:0002224=Reactome:REACT_9020, GO:0006282=PMID:10089880, GO:0045087=Reactome:REACT_6802, GO:0034166=Reactome:REACT_9027, GO:0045893=PMID:9305758, GO:0034146=Reactome:REACT_9061, GO:0034162=Reactome:REACT_9047} Q13404 Ubiquitin-conjugating enzyme E2 variant 1 protein 20130415 {GO:0005515=IPI, GO:0050852=TAS, GO:0034142=TAS, GO:0070423=TAS, GO:0000151=IDA, GO:0005634=TAS, GO:0035370=IDA, GO:0030154=NAS, GO:0035872=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0070534=IDA, GO:0051092=IMP, GO:0002755=TAS, GO:0043123=TAS, GO:0031371=IDA, GO:0000209=TAS, GO:0006355=TAS, GO:0038124=TAS, GO:0016881=IEA, GO:0038123=TAS, GO:0034134=TAS, GO:0002224=TAS, GO:0006282=TAS, GO:0045087=TAS, GO:0034166=TAS, GO:0045893=TAS, GO:0034146=TAS, GO:0034162=TAS} MyD88-dependent toll-like receptor signaling pathway, T cell receptor signaling pathway, cell differentiation, innate immune response, nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, nucleotide-binding oligomerization domain containing signaling pathway, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of transcription, DNA-dependent, protein K63-linked ubiquitination, protein polyubiquitination, regulation of DNA repair, regulation of transcription, DNA-dependent, toll-like receptor 10 signaling pathway, toll-like receptor 2 signaling pathway, toll-like receptor 4 signaling pathway, toll-like receptor 5 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor signaling pathway UBC13-UEV1A complex, cytoplasm, cytosol, nucleus, ubiquitin conjugating enzyme complex, ubiquitin ligase complex acid-amino acid ligase activity, protein binding Human UniProtKB:Q8ND25 UBE2V2 IntAct UniProtKB {GO:0051965=GO_REF:0000019, GO:0000209=PMID:10089880, GO:0005515=PMID:19549727, GO:0031372=PMID:16129784, GO:0016567=PMID:16129784, GO:0016881=GO_REF:0000002, GO:0008283=PMID:9418904, GO:0032436=GO_REF:0000019, GO:0005634=PMID:16129784, GO:0045739=GO_REF:0000019, GO:0043524=GO_REF:0000019, GO:0005737=PMID:16129784, GO:0006282=PMID:10089880, GO:0010976=GO_REF:0000019, GO:0000729=PMID:17349954} Q15819 Ubiquitin-conjugating enzyme E2 variant 2 protein 20130415 {GO:0051965=IEA, GO:0000209=TAS, GO:0005515=IPI, GO:0031372=IDA, GO:0016567=TAS, GO:0016881=IEA, GO:0008283=TAS, GO:0032436=IEA, GO:0005634=IDA, GO:0045739=IEA, GO:0043524=IEA, GO:0005737=TAS, GO:0006282=TAS, GO:0010976=IEA, GO:0000729=IMP} DNA double-strand break processing, cell proliferation, negative regulation of neuron apoptotic process, positive regulation of DNA repair, positive regulation of neuron projection development, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of synapse assembly, protein polyubiquitination, protein ubiquitination, regulation of DNA repair UBC13-MMS2 complex, cytoplasm, nucleus acid-amino acid ligase activity, protein binding Human UniProtKB:P61088 UBE2W UniProtKB UniProtKB {GO:0004842=PMID:21229326, GO:0006513=PMID:21229326, GO:0006281=GO_REF:0000037, GO:0070979=PMID:20061386, GO:0016881=GO_REF:0000002, GO:0043161=GO_REF:0000024, GO:0006515=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0005524=GO_REF:0000037, GO:0031625=PMID:19111657, GO:0071218=GO_REF:0000024} Q96B02 Ubiquitin-conjugating enzyme E2 W protein 20111104 {GO:0004842=IMP, GO:0006513=IMP, GO:0006281=IEA, GO:0070979=IDA, GO:0016881=IEA, GO:0043161=ISS, GO:0006515=ISS, GO:0005634=IEA, GO:0005524=IEA, GO:0031625=IPI, GO:0071218=ISS} DNA repair, cellular response to misfolded protein, misfolded or incompletely synthesized protein catabolic process, proteasomal ubiquitin-dependent protein catabolic process, protein K11-linked ubiquitination, protein monoubiquitination nucleus ATP binding, acid-amino acid ligase activity, ubiquitin protein ligase binding, ubiquitin-protein ligase activity Human UBE2Z HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0004842=GO_REF:0000003, GO:0016881=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037} Q9H832 Ubiquitin-conjugating enzyme E2 Z protein 20080818 {GO:0005737=IDA, GO:0004842=IEA, GO:0016881=IEA, GO:0005730=IDA, GO:0006915=IEA, GO:0005634=IDA, GO:0005524=IEA} apoptotic process cytoplasm, nucleolus, nucleus ATP binding, acid-amino acid ligase activity, ubiquitin-protein ligase activity Human UBE3A IntAct UniProtKB {GO:0005515=PMID:16493710, GO:0006511=PMID:8221889, GO:0004842=PMID:12890688, GO:0000502=GO_REF:0000037, GO:0060736=GO_REF:0000019, GO:0003713=GO_REF:0000019, GO:0014068=GO_REF:0000019, GO:0005634=GO_REF:0000033, GO:0005829=GO_REF:0000019, GO:0001541=GO_REF:0000019, GO:0005737=GO_REF:0000033, GO:0042787=GO_REF:0000033, GO:0007420=PMID:8988171, GO:0019048=GO_REF:0000037, GO:0045944=GO_REF:0000019, GO:0006508=PMID:8221889, GO:0070936=PMID:12890688, GO:0035037=GO_REF:0000019, GO:0030521=GO_REF:0000033} Q05086 Ubiquitin-protein ligase E3A protein 20130415 {GO:0005515=IPI, GO:0006511=TAS, GO:0004842=IDA, GO:0000502=IEA, GO:0060736=IEA, GO:0003713=IEA, GO:0014068=IEA, GO:0005634=IBA, GO:0005829=IEA, GO:0001541=IEA, GO:0005737=IBA, GO:0042787=IBA, GO:0007420=TAS, GO:0019048=IEA, GO:0045944=IEA, GO:0006508=TAS, GO:0070936=IDA, GO:0035037=IEA, GO:0030521=IBA} androgen receptor signaling pathway, brain development, ovarian follicle development, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of transcription from RNA polymerase II promoter, prostate gland growth, protein K48-linked ubiquitination, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, proteolysis, sperm entry, ubiquitin-dependent protein catabolic process, virus-host interaction cytoplasm, cytosol, nucleus, proteasome complex protein binding, transcription coactivator activity, ubiquitin-protein ligase activity Human UniProtKB:P06463 UBE3B RefGenome UniProtKB {GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000033, GO:0004842=GO_REF:0000033, GO:0042787=GO_REF:0000033, GO:0005634=GO_REF:0000033} Q7Z3V4 Ubiquitin-protein ligase E3B protein 20110204 {GO:0005622=IEA, GO:0005737=IBA, GO:0004842=IBA, GO:0042787=IBA, GO:0005634=IBA} protein ubiquitination involved in ubiquitin-dependent protein catabolic process cytoplasm, intracellular, nucleus ubiquitin-protein ligase activity Human PANTHER:PTN000134256 UBE3C UniProtKB UniProtKB {GO:0005622=PMID:11278995, GO:0000209=PMID:11278995, GO:0005515=PMID:12692129, GO:0004842=PMID:11278995, GO:0005737=GO_REF:0000033, GO:0000502=GO_REF:0000037, GO:0042787=GO_REF:0000033, GO:0005634=GO_REF:0000033} Q15386 Ubiquitin-protein ligase E3C protein 20040420 {GO:0005622=IC, GO:0000209=IDA, GO:0005515=IPI, GO:0004842=IDA, GO:0005737=IBA, GO:0000502=IEA, GO:0042787=IBA, GO:0005634=IBA} protein polyubiquitination, protein ubiquitination involved in ubiquitin-dependent protein catabolic process cytoplasm, intracellular, nucleus, proteasome complex protein binding, ubiquitin-protein ligase activity Human UBE4A IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0000209=GO_REF:0000019, GO:0006511=GO_REF:0000002, GO:0005737=GO_REF:0000019, GO:0034450=GO_REF:0000019, GO:0000151=GO_REF:0000002} Q14139 Ubiquitin conjugation factor E4 A protein 20130415 {GO:0005515=IPI, GO:0000209=IEA, GO:0006511=IEA, GO:0005737=IEA, GO:0034450=IEA, GO:0000151=IEA} protein polyubiquitination, ubiquitin-dependent protein catabolic process cytoplasm, ubiquitin ligase complex protein binding, ubiquitin-ubiquitin ligase activity Human UniProtKB:Q7Z434 UBE4B UniProtKB UniProtKB {GO:0000209=GO_REF:0000019, GO:0006511=GO_REF:0000002, GO:0034976=GO_REF:0000019, GO:0034450=GO_REF:0000019, GO:0000151=PMID:11802788, GO:0006915=PMID:11802788, GO:0005634=GO_REF:0000019, GO:0031175=GO_REF:0000019, GO:0005737=GO_REF:0000024, GO:0042787=PMID:11802788, GO:0003222=GO_REF:0000019, GO:0019899=GO_REF:0000024, GO:0009411=PMID:11802788} O95155 Ubiquitin conjugation factor E4 B protein 20030820 {GO:0000209=IEA, GO:0006511=IEA, GO:0034976=IEA, GO:0034450=IEA, GO:0000151=TAS, GO:0006915=IDA, GO:0005634=IEA, GO:0031175=IEA, GO:0005737=ISS, GO:0042787=TAS, GO:0003222=IEA, GO:0019899=ISS, GO:0009411=IDA} apoptotic process, neuron projection development, protein polyubiquitination, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, response to UV, response to endoplasmic reticulum stress, ubiquitin-dependent protein catabolic process, ventricular trabecula myocardium morphogenesis cytoplasm, nucleus, ubiquitin ligase complex enzyme binding, ubiquitin-ubiquitin ligase activity Human UBFD1 null null {} null null null null {} null null null UBIAD1 UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0005737=PMID:11314041, GO:0009234=GO_REF:0000041, GO:0016020=PMID:11314041, GO:0005783=PMID:20953171, GO:0005789=GO_REF:0000039, GO:0005634=PMID:11314041, GO:0016021=GO_REF:0000037, GO:0042371=PMID:20953171, GO:0004659=PMID:20953171} Q9Y5Z9 UbiA prenyltransferase domain-containing protein 1 protein 20101105 {GO:0005739=IEA, GO:0005737=IDA, GO:0009234=IEA, GO:0016020=IDA, GO:0005783=IDA, GO:0005789=IEA, GO:0005634=IDA, GO:0016021=IEA, GO:0042371=IDA, GO:0004659=IDA} menaquinone biosynthetic process, vitamin K biosynthetic process cytoplasm, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, membrane, mitochondrion, nucleus prenyltransferase activity Human UBL3 LIFEdb UniProtKB {GO:0005622=GO_REF:0000054, GO:0005886=GO_REF:0000039} O95164 Ubiquitin-like protein 3 protein 20100607 {GO:0005622=IDA, GO:0005886=IEA} intracellular, plasma membrane Human UBL4A IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0019787=PMID:2829204, GO:0006810=GO_REF:0000037, GO:0071816=PMID:20676083, GO:0006464=PMID:2829204, GO:0071818=PMID:20676083, GO:0005829=PMID:20676083} P11441 Ubiquitin-like protein 4A protein 20130415 {GO:0005515=IPI, GO:0019787=TAS, GO:0006810=IEA, GO:0071816=IMP, GO:0006464=TAS, GO:0071818=IDA, GO:0005829=IDA} cellular protein modification process, tail-anchored membrane protein insertion into ER membrane, transport BAT3 complex, cytosol protein binding, small conjugating protein ligase activity Human UniProtKB:P12504 UBL5 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005737=PMID:11161819} Q9BZL1 Ubiquitin-like protein 5 protein 20061026 {GO:0008150=ND, GO:0003674=ND, GO:0005737=IDA} biological_process cytoplasm molecular_function Human UBL7 null null {} null null null null {} null null null UBLCP1 HPA UniProtKB {GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0004721=GO_REF:0000003} Q8WVY7 Ubiquitin-like domain-containing CTD phosphatase 1 protein 20110516 {GO:0005730=IDA, GO:0005634=IDA, GO:0004721=IEA} nucleolus, nucleus phosphoprotein phosphatase activity Human UBN1 PINC UniProtKB {GO:0005515=PMID:18823282, GO:0003700=PMID:10725330, GO:0006357=PMID:10725330, GO:0010923=PMID:19389623, GO:0016605=GO_REF:0000039, GO:0019048=GO_REF:0000037, GO:0005634=PMID:10725330, GO:0005923=GO_REF:0000024, GO:0003677=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q9NPG3 Ubinuclein-1 protein 20061106 {GO:0005515=IPI, GO:0003700=TAS, GO:0006357=TAS, GO:0010923=IDA, GO:0016605=IEA, GO:0019048=IEA, GO:0005634=TAS, GO:0005923=ISS, GO:0003677=IEA, GO:0016568=IEA} chromatin modification, negative regulation of phosphatase activity, regulation of transcription from RNA polymerase II promoter, virus-host interaction PML body, nucleus, tight junction DNA binding, protein binding, sequence-specific DNA binding transcription factor activity Human UBN2 HPA UniProtKB {GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q6ZU65 Ubinuclein-2 protein 20100326 {GO:0005730=IDA, GO:0005634=IDA} nucleolus, nucleus NOT Human UBOX5 UniProtKB UniProtKB {GO:0000209=GO_REF:0000019, GO:0034450=GO_REF:0000019, GO:0000151=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000039} O94941 RING finger protein 37 protein 20130413 {GO:0000209=IEA, GO:0034450=IEA, GO:0000151=IEA, GO:0008270=IEA, GO:0005634=IEA} protein polyubiquitination nucleus, ubiquitin ligase complex ubiquitin-ubiquitin ligase activity, zinc ion binding Human UniProtKB-SubCell:SL-0191 UBP1 PINC UniProtKB {GO:0003700=PMID:8114710, GO:0006357=PMID:8114710, GO:0003714=PMID:8114710, GO:0005634=PMID:8114710, GO:0001525=GO_REF:0000019, GO:0019079=PMID:8114710, GO:0045892=PMID:8114710, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9NZI7 Upstream-binding protein 1 protein 20031119 {GO:0003700=TAS, GO:0006357=TAS, GO:0003714=TAS, GO:0005634=TAS, GO:0001525=IEA, GO:0019079=TAS, GO:0045892=TAS, GO:0003677=IEA, GO:0006351=IEA} angiogenesis, negative regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent, viral genome replication nucleus DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human UBQLN1 LIFEdb UniProtKB {GO:0005515=PMID:12095988, GO:0043234=GO_REF:0000054, GO:0001666=PMID:12095988, GO:0048471=PMID:12095988, GO:0005737=PMID:12634373, GO:0000502=GO_REF:0000037, GO:0005783=PMID:12095988, GO:0006915=PMID:12095988, GO:0031396=PMID:12634373, GO:0005634=GO_REF:0000039, GO:0019900=PMID:11853878} Q9UMX0 Ubiquilin-1 protein 20100607 {GO:0005515=IPI, GO:0043234=IDA, GO:0001666=IMP, GO:0048471=IDA, GO:0005737=IMP, GO:0000502=IEA, GO:0005783=IDA, GO:0006915=IMP, GO:0031396=IDA, GO:0005634=IEA, GO:0019900=IPI} apoptotic process, regulation of protein ubiquitination, response to hypoxia cytoplasm, endoplasmic reticulum, nucleus, perinuclear region of cytoplasm, proteasome complex, protein complex kinase binding, protein binding Human UBQLN2 HPA UniProtKB {GO:0005515=PMID:17098253, GO:0008219=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005634=GO_REF:0000039} Q9UHD9 Ubiquilin-2 protein 20080818 {GO:0005515=IPI, GO:0008219=IEA, GO:0005737=IDA, GO:0005886=IDA, GO:0005634=IEA} cell death cytoplasm, nucleus, plasma membrane protein binding Human UBQLN4 IntAct UniProtKB {GO:0031597=PMID:15280365, GO:0005515=PMID:16713569, GO:0031595=PMID:15280365, GO:0005737=PMID:11001934, GO:0048471=GO_REF:0000039, GO:0005789=GO_REF:0000024, GO:0032434=PMID:15280365, GO:0005634=PMID:11001934, GO:0031593=PMID:15280365, GO:0005829=GO_REF:0000024} Q9NRR5 Ubiquilin-4 protein 20130415 {GO:0031597=IDA, GO:0005515=IPI, GO:0031595=IDA, GO:0005737=IDA, GO:0048471=IEA, GO:0005789=ISS, GO:0032434=IMP, GO:0005634=IDA, GO:0031593=IDA, GO:0005829=ISS} regulation of proteasomal ubiquitin-dependent protein catabolic process cytoplasm, cytosol, cytosolic proteasome complex, endoplasmic reticulum membrane, nuclear proteasome complex, nucleus, perinuclear region of cytoplasm polyubiquitin binding, protein binding Human UniProtKB:Q9Y5P3 UBQLNL null null {} null null null null {} null null null UBR1 UniProtKB UniProtKB {GO:0071233=PMID:20298436, GO:0006511=GO_REF:0000019, GO:0032007=PMID:20298436, GO:0004842=GO_REF:0000019, GO:0000502=GO_REF:0000019, GO:0070728=PMID:20298436, GO:0000151=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005829=GO_REF:0000039} Q8IWV7 E3 ubiquitin-protein ligase UBR1 protein 20110622 {GO:0071233=IDA, GO:0006511=IEA, GO:0032007=IMP, GO:0004842=IEA, GO:0000502=IEA, GO:0070728=IDA, GO:0000151=IEA, GO:0008270=IEA, GO:0005829=IEA} cellular response to leucine, negative regulation of TOR signaling cascade, ubiquitin-dependent protein catabolic process cytosol, proteasome complex, ubiquitin ligase complex leucine binding, ubiquitin-protein ligase activity, zinc ion binding Human UBR2 HPA UniProtKB {GO:0005515=PMID:22190034, GO:0006511=GO_REF:0000019, GO:0004842=GO_REF:0000019, GO:0006342=GO_REF:0000024, GO:0032007=PMID:20298436, GO:0005886=GO_REF:0000052, GO:0033522=GO_REF:0000024, GO:0070728=PMID:20298436, GO:0005730=GO_REF:0000052, GO:0000151=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0007283=GO_REF:0000019, GO:0071233=PMID:20298436, GO:0008270=GO_REF:0000002, GO:0000785=GO_REF:0000019, GO:0007141=GO_REF:0000019} Q8IWV8 E3 ubiquitin-protein ligase UBR2 protein 20101115 {GO:0005515=IPI, GO:0006511=IEA, GO:0004842=IEA, GO:0006342=ISS, GO:0032007=IMP, GO:0005886=IDA, GO:0033522=ISS, GO:0070728=IDA, GO:0005730=IDA, GO:0000151=IEA, GO:0005634=IDA, GO:0007283=IEA, GO:0071233=IDA, GO:0008270=IEA, GO:0000785=IEA, GO:0007141=IEA} cellular response to leucine, chromatin silencing, histone H2A ubiquitination, male meiosis I, negative regulation of TOR signaling cascade, spermatogenesis, ubiquitin-dependent protein catabolic process chromatin, nucleolus, nucleus, plasma membrane, ubiquitin ligase complex leucine binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human UBR3 UniProtKB UniProtKB {GO:0007608=GO_REF:0000024, GO:0006511=GO_REF:0000024, GO:0004842=GO_REF:0000024, GO:0001967=GO_REF:0000024, GO:0042048=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0009790=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0001701=GO_REF:0000019} Q6ZT12 E3 ubiquitin-protein ligase UBR3 protein 20071204 {GO:0007608=ISS, GO:0006511=ISS, GO:0004842=ISS, GO:0001967=ISS, GO:0042048=IEA, GO:0008270=IEA, GO:0009790=ISS, GO:0016021=IEA, GO:0001701=IEA} embryo development, in utero embryonic development, olfactory behavior, sensory perception of smell, suckling behavior, ubiquitin-dependent protein catabolic process integral to membrane ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q5U430 UBR4 UniProtKB UniProtKB {GO:0005516=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0004842=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0016874=GO_REF:0000038, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0005856=GO_REF:0000039} Q5T4S7 E3 ubiquitin-protein ligase UBR4 protein 20130413 {GO:0005516=IEA, GO:0005737=IEA, GO:0004842=IEA, GO:0019048=IEA, GO:0016874=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0016021=IEA, GO:0005856=IEA} virus-host interaction cytoplasm, cytoskeleton, integral to membrane, nucleus calmodulin binding, ligase activity, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB-SubCell:SL-0090 UBR5 BHF-UCL UniProtKB {GO:0000209=PMID:21118991, GO:0005515=PMID:21118991, GO:2000780=PMID:22884692, GO:0050847=PMID:12011095, GO:0043130=GO_REF:0000002, GO:0006511=PMID:10030672, GO:0004842=PMID:10030672, GO:0033160=PMID:21118991, GO:0008283=PMID:10030672, GO:0003723=GO_REF:0000002, GO:0034450=PMID:21118991, GO:0090263=PMID:21118991, GO:0005634=PMID:21118991, GO:0035413=PMID:21118991, GO:0006974=PMID:12011095, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000033, GO:0006281=GO_REF:0000037, GO:1901315=PMID:22884692, GO:0042787=GO_REF:0000033, GO:0008270=GO_REF:0000002} O95071 E3 ubiquitin-protein ligase UBR5 protein 20101220 {GO:0000209=IDA, GO:0005515=IPI, GO:2000780=IMP, GO:0050847=IDA, GO:0043130=IEA, GO:0006511=TAS, GO:0004842=TAS, GO:0033160=IMP, GO:0008283=TAS, GO:0003723=IEA, GO:0034450=IDA, GO:0090263=IMP, GO:0005634=IDA, GO:0035413=IMP, GO:0006974=IDA, GO:0005622=IEA, GO:0005737=IBA, GO:0006281=IEA, GO:1901315=IMP, GO:0042787=IBA, GO:0008270=IEA} DNA repair, cell proliferation, negative regulation of double-strand break repair, negative regulation of histone H2A K63-linked ubiquitination, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of catenin import into nucleus, positive regulation of protein import into nucleus, translocation, progesterone receptor signaling pathway, protein polyubiquitination, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, response to DNA damage stimulus, ubiquitin-dependent protein catabolic process cytoplasm, intracellular, nucleus RNA binding, protein binding, ubiquitin binding, ubiquitin-protein ligase activity, ubiquitin-ubiquitin ligase activity, zinc ion binding Human UBR7 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0004842=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q8N806 Putative E3 ubiquitin-protein ligase UBR7 protein 20081106 {GO:0008150=ND, GO:0003674=ND, GO:0004842=IEA, GO:0008270=IEA} biological_process molecular_function, ubiquitin-protein ligase activity, zinc ion binding Human UBTD1 null null {} null null null null {} null null null UBTD2 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q8WUN7 Ubiquitin domain-containing protein 2 protein 20110516 {GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA} cytoplasm, nucleolus, nucleus Human UBTF HPA UniProtKB {GO:0010468=GO_REF:0000019, GO:0005515=PMID:21150319, GO:0010467=Reactome:REACT_71, GO:0007566=GO_REF:0000019, GO:0006356=PMID:2330041, GO:0001832=GO_REF:0000019, GO:0006363=Reactome:REACT_1074, GO:0006362=Reactome:REACT_2204, GO:0005730=GO_REF:0000052, GO:0006361=Reactome:REACT_2232, GO:0005634=GO_REF:0000019, GO:0006360=Reactome:REACT_1309, GO:0003677=GO_REF:0000037, GO:0005737=GO_REF:0000019, GO:0045943=GO_REF:0000024, GO:0005654=Reactome:REACT_2228} P17480 Nucleolar transcription factor 1 protein 20101115 {GO:0010468=IEA, GO:0005515=IPI, GO:0010467=TAS, GO:0007566=IEA, GO:0006356=TAS, GO:0001832=IEA, GO:0006363=TAS, GO:0006362=TAS, GO:0005730=IDA, GO:0006361=TAS, GO:0005634=IEA, GO:0006360=TAS, GO:0003677=IEA, GO:0005737=IEA, GO:0045943=ISS, GO:0005654=TAS} blastocyst growth, embryo implantation, gene expression, positive regulation of transcription from RNA polymerase I promoter, regulation of gene expression, regulation of transcription from RNA polymerase I promoter, termination of RNA polymerase I transcription, transcription elongation from RNA polymerase I promoter, transcription from RNA polymerase I promoter, transcription initiation from RNA polymerase I promoter cytoplasm, nucleolus, nucleoplasm, nucleus DNA binding, protein binding Human UBXN1 BHF-UCL UniProtKB {GO:0005515=PMID:20351172, GO:0043130=PMID:18775313, GO:0000502=PMID:15362974, GO:0005634=GO_REF:0000019, GO:0032435=PMID:20351172, GO:0071796=PMID:20351172, GO:0030425=GO_REF:0000019, GO:0005737=PMID:10942595, GO:0043025=GO_REF:0000019, GO:0051117=PMID:15362974, GO:0043161=PMID:15362974, GO:0034098=PMID:18775313, GO:0031397=PMID:20351172, GO:0031625=PMID:18775313, GO:0031593=PMID:15362974} Q04323 UBX domain-containing protein 1 protein 20110707 {GO:0005515=IPI, GO:0043130=IDA, GO:0000502=IDA, GO:0005634=IEA, GO:0032435=IDA, GO:0071796=IDA, GO:0030425=IEA, GO:0005737=IDA, GO:0043025=IEA, GO:0051117=IPI, GO:0043161=NAS, GO:0034098=IDA, GO:0031397=IDA, GO:0031625=IDA, GO:0031593=IDA} negative regulation of proteasomal ubiquitin-dependent protein catabolic process, negative regulation of protein ubiquitination, proteasomal ubiquitin-dependent protein catabolic process Cdc48p-Npl4p-Ufd1p AAA ATPase complex, cytoplasm, dendrite, neuronal cell body, nucleus, proteasome complex ATPase binding, K6-linked polyubiquitin binding, polyubiquitin binding, protein binding, ubiquitin binding, ubiquitin protein ligase binding Human UBXN10 null null {} null null null null {} null null null UBXN11 UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0005856=GO_REF:0000039} Q5T124 UBX domain-containing protein 11 protein 20130413 {GO:0005737=IEA, GO:0005856=IEA} cytoplasm, cytoskeleton Human UniProtKB-SubCell:SL-0090 UBXN2A ENSEMBL UniProtKB {GO:0010468=GO_REF:0000019, GO:0005801=GO_REF:0000019, GO:0042176=GO_REF:0000019, GO:0005783=GO_REF:0000019, GO:0033130=GO_REF:0000019, GO:0031396=GO_REF:0000019, GO:0005829=GO_REF:0000019} P68543 UBX domain-containing protein 2A protein 20130413 {GO:0010468=IEA, GO:0005801=IEA, GO:0042176=IEA, GO:0005783=IEA, GO:0033130=IEA, GO:0031396=IEA, GO:0005829=IEA} regulation of gene expression, regulation of protein catabolic process, regulation of protein ubiquitination cis-Golgi network, cytosol, endoplasmic reticulum acetylcholine receptor binding Human Ensembl:ENSMUSP00000020962 UBXN2B UniProtKB UniProtKB {GO:0005794=GO_REF:0000039, GO:0005783=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0005829=GO_REF:0000039} Q14CS0 UBX domain-containing protein 2B protein 20130413 {GO:0005794=IEA, GO:0005783=IEA, GO:0005634=IEA, GO:0005829=IEA} Golgi apparatus, cytosol, endoplasmic reticulum, nucleus Human UniProtKB-SubCell:SL-0091 UBXN4 HPA UniProtKB {GO:0005515=PMID:18775313, GO:0006986=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0005783=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005789=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0005635=GO_REF:0000039} Q92575 UBX domain-containing protein 4 protein 20110516 {GO:0005515=IPI, GO:0006986=IEA, GO:0005737=IDA, GO:0005783=IDA, GO:0005730=IDA, GO:0005789=IEA, GO:0005634=IDA, GO:0005635=IEA} response to unfolded protein cytoplasm, endoplasmic reticulum, endoplasmic reticulum membrane, nuclear envelope, nucleolus, nucleus protein binding Human UBXN6 HPA UniProtKB {GO:0005515=PMID:18775313, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000039, GO:0005815=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005575=GO_REF:0000015} Q9BZV1 UBX domain-containing protein 6 protein 20111111 {GO:0005515=IPI, GO:0008150=ND, GO:0003674=ND, GO:0005737=IEA, GO:0005815=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005575=ND} biological_process cellular_component, cytoplasm, microtubule organizing center, nucleolus, nucleus molecular_function, protein binding Human UBXN7 BHF-UCL UniProtKB {GO:0005515=PMID:18775313, GO:0043130=PMID:18775313, GO:0034098=PMID:18775313, GO:0031625=PMID:18775313, GO:0008134=PMID:18775313} O94888 UBX domain-containing protein 7 protein 20110707 {GO:0005515=IPI, GO:0043130=IDA, GO:0034098=IDA, GO:0031625=IDA, GO:0008134=IPI} Cdc48p-Npl4p-Ufd1p AAA ATPase complex protein binding, transcription factor binding, ubiquitin binding, ubiquitin protein ligase binding Human UBXN8 PINC UniProtKB {GO:0007338=PMID:9027507} O00124 UBX domain-containing protein 8 protein 20030904 {GO:0007338=TAS} single fertilization Human UCHL1 BHF-UCL UniProtKB {GO:0005515=PMID:20029029, GO:0006511=GO_REF:0000019, GO:0030424=GO_REF:0000019, GO:0008219=GO_REF:0000037, GO:0043130=PMID:9521656, GO:0016579=PMID:9521656, GO:0005886=PMID:19477270, GO:0008283=GO_REF:0000019, GO:0016874=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0031694=PMID:19477270, GO:0005829=GO_REF:0000019, GO:0048747=GO_REF:0000019, GO:0005622=GO_REF:0000002, GO:0050905=GO_REF:0000019, GO:0007412=GO_REF:0000019, GO:0005737=PMID:19477270, GO:0043407=PMID:19477270, GO:0007628=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0008242=PMID:9521656, GO:0006950=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0019233=GO_REF:0000019, GO:0004197=PMID:8639624, GO:0005789=GO_REF:0000039, GO:0019896=GO_REF:0000019, GO:0042755=GO_REF:0000019, GO:0004221=PMID:9521656} P09936 Ubiquitin carboxyl-terminal hydrolase isozyme L1 protein 20100624 {GO:0005515=IPI, GO:0006511=IEA, GO:0030424=IEA, GO:0008219=IEA, GO:0043130=IDA, GO:0016579=IDA, GO:0005886=IDA, GO:0008283=IEA, GO:0016874=IEA, GO:0005634=IDA, GO:0031694=IPI, GO:0005829=IEA, GO:0048747=IEA, GO:0005622=IEA, GO:0050905=IEA, GO:0007412=IEA, GO:0005737=IDA, GO:0043407=IDA, GO:0007628=IEA, GO:0043025=IEA, GO:0008242=IDA, GO:0006950=IEA, GO:0005730=IDA, GO:0019233=IEA, GO:0004197=IDA, GO:0005789=IEA, GO:0019896=IEA, GO:0042755=IEA, GO:0004221=TAS} adult walking behavior, axon target recognition, axon transport of mitochondrion, cell death, cell proliferation, eating behavior, muscle fiber development, negative regulation of MAP kinase activity, neuromuscular process, protein deubiquitination, response to stress, sensory perception of pain, ubiquitin-dependent protein catabolic process axon, cytoplasm, cytosol, endoplasmic reticulum membrane, intracellular, neuronal cell body, nucleolus, nucleus, plasma membrane alpha-2A adrenergic receptor binding, cysteine-type endopeptidase activity, ligase activity, omega peptidase activity, protein binding, ubiquitin binding, ubiquitin thiolesterase activity Human UCHL3 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0005739=GO_REF:0000052, GO:0030163=PMID:21762696, GO:0043130=PMID:19154770, GO:0006511=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008233=PMID:21762696, GO:0004221=GO_REF:0000002, GO:0008234=GO_REF:0000037} Q5TBK7 Ubiquitin carboxyl-terminal hydrolase isozyme L3 protein 20130413 {GO:0005622=IEA, GO:0005739=IDA, GO:0030163=IDA, GO:0043130=IDA, GO:0006511=IEA, GO:0005737=IDA, GO:0005634=IDA, GO:0008233=IDA, GO:0004221=IEA, GO:0008234=IEA} protein catabolic process, ubiquitin-dependent protein catabolic process cytoplasm, intracellular, mitochondrion, nucleus cysteine-type peptidase activity, peptidase activity, ubiquitin binding, ubiquitin thiolesterase activity Human InterPro:IPR001578 UCHL5 HPA UniProtKB {GO:0005515=PMID:18922472, GO:0006511=GO_REF:0000002, GO:0016579=PMID:18922472, GO:0004843=PMID:18922472, GO:0004866=PMID:18162577, GO:0005634=GO_REF:0000052, GO:0005829=PMID:18922472, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0007179=Reactome:REACT_120850, GO:0008242=GO_REF:0000002, GO:0030512=Reactome:REACT_120727, GO:0006355=GO_REF:0000037, GO:0000502=GO_REF:0000037, GO:0006310=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0048853=GO_REF:0000019, GO:0010951=PMID:18162577, GO:0031011=PMID:18922472, GO:0006281=GO_REF:0000037, GO:0021670=GO_REF:0000019, GO:0061136=PMID:18162577, GO:0070628=PMID:18162577, GO:0030901=GO_REF:0000019, GO:0004221=GO_REF:0000002} Q9Y5K5 Ubiquitin carboxyl-terminal hydrolase isozyme L5 protein 20080818 {GO:0005515=IPI, GO:0006511=IEA, GO:0016579=IDA, GO:0004843=IDA, GO:0004866=IMP, GO:0005634=IDA, GO:0005829=IDA, GO:0005622=IEA, GO:0005737=IDA, GO:0007179=TAS, GO:0008242=IEA, GO:0030512=TAS, GO:0006355=IEA, GO:0000502=IEA, GO:0006310=IEA, GO:0006351=IEA, GO:0048853=IEA, GO:0010951=IMP, GO:0031011=IDA, GO:0006281=IEA, GO:0021670=IEA, GO:0061136=IMP, GO:0070628=IDA, GO:0030901=IEA, GO:0004221=IEA} DNA recombination, DNA repair, forebrain morphogenesis, lateral ventricle development, midbrain development, negative regulation of endopeptidase activity, negative regulation of transforming growth factor beta receptor signaling pathway, protein deubiquitination, regulation of proteasomal protein catabolic process, regulation of transcription, DNA-dependent, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, ubiquitin-dependent protein catabolic process Ino80 complex, cytoplasm, cytosol, intracellular, nucleus, proteasome complex endopeptidase inhibitor activity, omega peptidase activity, proteasome binding, protein binding, ubiquitin thiolesterase activity, ubiquitin-specific protease activity Human UCK1 Reactome UniProtKB {GO:0044211=GO_REF:0000041, GO:0044206=GO_REF:0000041, GO:0004849=GO_REF:0000003, GO:0016301=GO_REF:0000038, GO:0016773=GO_REF:0000002, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0043097=Reactome:REACT_655, GO:0019206=Reactome:REACT_2062, GO:0006206=Reactome:REACT_957, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_2062} Q9HA47 Uridine-cytidine kinase 1 protein 20130213 {GO:0044211=IEA, GO:0044206=IEA, GO:0004849=IEA, GO:0016301=IEA, GO:0016773=IEA, GO:0055086=TAS, GO:0044281=TAS, GO:0043097=TAS, GO:0019206=EXP, GO:0006206=TAS, GO:0005524=IEA, GO:0005829=TAS} CTP salvage, UMP salvage, nucleobase-containing small molecule metabolic process, pyrimidine nucleobase metabolic process, pyrimidine nucleoside salvage, small molecule metabolic process cytosol ATP binding, kinase activity, nucleoside kinase activity, phosphotransferase activity, alcohol group as acceptor, uridine kinase activity Human UCK2 Reactome UniProtKB {GO:0007631=GO_REF:0000019, GO:0004849=GO_REF:0000003, GO:0044206=GO_REF:0000041, GO:0044211=GO_REF:0000041, GO:0071453=GO_REF:0000019, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0043097=Reactome:REACT_655, GO:0005575=GO_REF:0000015, GO:0019206=Reactome:REACT_2162, GO:0005524=GO_REF:0000037, GO:0048678=GO_REF:0000019, GO:0043231=GO_REF:0000019, GO:0005829=Reactome:REACT_2162, GO:0016773=GO_REF:0000002, GO:0006206=Reactome:REACT_957} Q9BZX2 Uridine-cytidine kinase 2 protein 20130213 {GO:0007631=IEA, GO:0004849=IEA, GO:0044206=IEA, GO:0044211=IEA, GO:0071453=IEA, GO:0055086=TAS, GO:0044281=TAS, GO:0043097=TAS, GO:0005575=ND, GO:0019206=EXP, GO:0005524=IEA, GO:0048678=IEA, GO:0043231=IEA, GO:0005829=TAS, GO:0016773=IEA, GO:0006206=TAS} CTP salvage, UMP salvage, cellular response to oxygen levels, feeding behavior, nucleobase-containing small molecule metabolic process, pyrimidine nucleobase metabolic process, pyrimidine nucleoside salvage, response to axon injury, small molecule metabolic process cellular_component, cytosol, intracellular membrane-bounded organelle ATP binding, nucleoside kinase activity, phosphotransferase activity, alcohol group as acceptor, uridine kinase activity Human UCKL1 HPA UniProtKB {GO:0005783=GO_REF:0000052, GO:0044211=GO_REF:0000041, GO:0044206=GO_REF:0000041, GO:0004849=GO_REF:0000003, GO:0019048=GO_REF:0000037, GO:0016773=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0005524=GO_REF:0000037} Q9NWZ5 Uridine-cytidine kinase-like 1 protein 20080205 {GO:0005783=IDA, GO:0044211=IEA, GO:0044206=IEA, GO:0004849=IEA, GO:0019048=IEA, GO:0016773=IEA, GO:0005634=IEA, GO:0005524=IEA} CTP salvage, UMP salvage, virus-host interaction endoplasmic reticulum, nucleus ATP binding, phosphotransferase activity, alcohol group as acceptor, uridine kinase activity Human UCN PINC UniProtKB {GO:0032755=GO_REF:0000019, GO:0005515=PMID:18234674, GO:0030307=GO_REF:0000019, GO:2000252=GO_REF:0000019, GO:0030157=GO_REF:0000019, GO:0031175=GO_REF:0000019, GO:0046888=GO_REF:0000019, GO:0007218=GO_REF:0000019, GO:0035483=GO_REF:0000019, GO:0005184=PMID:8612563, GO:0032355=GO_REF:0000019, GO:0006979=GO_REF:0000019, GO:0008306=GO_REF:0000019, GO:0051966=GO_REF:0000019, GO:0007565=GO_REF:0000019, GO:0045740=GO_REF:0000019, GO:1901215=GO_REF:0000019, GO:0051384=GO_REF:0000019, GO:0045792=GO_REF:0000019, GO:0032967=GO_REF:0000019, GO:0007186=PMID:8612563, GO:0030819=GO_REF:0000019, GO:0032099=GO_REF:0000019, GO:0045776=GO_REF:0000019, GO:0090280=GO_REF:0000019, GO:0030425=GO_REF:0000019, GO:0009060=GO_REF:0000019, GO:0033138=GO_REF:0000019, GO:0006954=GO_REF:0000019, GO:0060452=GO_REF:0000019, GO:0045909=GO_REF:0000019, GO:0043196=GO_REF:0000019, GO:0060455=GO_REF:0000019, GO:0043204=GO_REF:0000019, GO:0043679=GO_REF:0000019, GO:0051461=GO_REF:0000019, GO:0034199=GO_REF:0000019, GO:2000987=GO_REF:0000019, GO:0051430=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0051431=GO_REF:0000019, GO:0045727=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0010628=GO_REF:0000019, GO:0042756=GO_REF:0000019, GO:0010629=GO_REF:0000019, GO:0048265=GO_REF:0000019, GO:0043117=GO_REF:0000019, GO:0046811=GO_REF:0000019} P55089 Urocortin protein 20030904 {GO:0032755=IEA, GO:0005515=IPI, GO:0030307=IEA, GO:2000252=IEA, GO:0030157=IEA, GO:0031175=IEA, GO:0046888=IEA, GO:0007218=IEA, GO:0035483=IEA, GO:0005184=TAS, GO:0032355=IEA, GO:0006979=IEA, GO:0008306=IEA, GO:0051966=IEA, GO:0007565=IEA, GO:0045740=IEA, GO:1901215=IEA, GO:0051384=IEA, GO:0045792=IEA, GO:0032967=IEA, GO:0007186=TAS, GO:0030819=IEA, GO:0032099=IEA, GO:0045776=IEA, GO:0090280=IEA, GO:0030425=IEA, GO:0009060=IEA, GO:0033138=IEA, GO:0006954=IEA, GO:0060452=IEA, GO:0045909=IEA, GO:0043196=IEA, GO:0060455=IEA, GO:0043204=IEA, GO:0043679=IEA, GO:0051461=IEA, GO:0034199=IEA, GO:2000987=IEA, GO:0051430=IEA, GO:0043066=IEA, GO:0051431=IEA, GO:0045727=IEA, GO:0005576=IEA, GO:0010628=IEA, GO:0042756=IEA, GO:0010629=IEA, GO:0048265=IEA, GO:0043117=IEA, GO:0046811=IEA} G-protein coupled receptor signaling pathway, activation of protein kinase A activity, aerobic respiration, associative learning, drinking behavior, female pregnancy, gastric emptying, inflammatory response, negative regulation of apoptotic process, negative regulation of appetite, negative regulation of blood pressure, negative regulation of cell size, negative regulation of feeding behavior, negative regulation of gastric acid secretion, negative regulation of gene expression, negative regulation of hormone secretion, negative regulation of neuron death, neuron projection development, neuropeptide signaling pathway, pancreatic juice secretion, positive regulation of DNA replication, positive regulation of behavioral fear response, positive regulation of cAMP biosynthetic process, positive regulation of calcium ion import, positive regulation of cardiac muscle contraction, positive regulation of cell growth, positive regulation of collagen biosynthetic process, positive regulation of corticotropin secretion, positive regulation of gene expression, positive regulation of interleukin-6 production, positive regulation of peptidyl-serine phosphorylation, positive regulation of translation, positive regulation of vascular permeability, positive regulation of vasodilation, regulation of synaptic transmission, glutamatergic, response to estradiol stimulus, response to glucocorticoid stimulus, response to oxidative stress, response to pain axon terminus, dendrite, extracellular region, perikaryon, varicosity corticotropin-releasing hormone receptor 1 binding, corticotropin-releasing hormone receptor 2 binding, histone deacetylase inhibitor activity, neuropeptide hormone activity, protein binding Human UCN2 UniProtKB UniProtKB {GO:0008283=GO_REF:0000019, GO:0051431=GO_REF:0000019, GO:0042562=PMID:11329063, GO:0033685=GO_REF:0000019, GO:0007586=PMID:11329063, GO:0005102=PMID:11329063, GO:0006950=PMID:11329063, GO:0046882=GO_REF:0000019, GO:0071456=GO_REF:0000019, GO:0005576=PMID:11329063, GO:0005615=GO_REF:0000019, GO:0071385=GO_REF:0000019, GO:0005179=GO_REF:0000037, GO:0010629=GO_REF:0000019, GO:0006171=PMID:11329063} Q96RP3 Urocortin-2 protein 20090317 {GO:0008283=IEA, GO:0051431=IEA, GO:0042562=IPI, GO:0033685=IEA, GO:0007586=NAS, GO:0005102=IPI, GO:0006950=NAS, GO:0046882=IEA, GO:0071456=IEA, GO:0005576=NAS, GO:0005615=IEA, GO:0071385=IEA, GO:0005179=IEA, GO:0010629=IEA, GO:0006171=IEP} cAMP biosynthetic process, cell proliferation, cellular response to glucocorticoid stimulus, cellular response to hypoxia, digestion, negative regulation of follicle-stimulating hormone secretion, negative regulation of gene expression, negative regulation of luteinizing hormone secretion, response to stress extracellular region, extracellular space corticotropin-releasing hormone receptor 2 binding, hormone activity, hormone binding, receptor binding Human UniProtKB:Q13324 UCN3 ENSEMBL UniProtKB {GO:0035902=GO_REF:0000019, GO:0051412=GO_REF:0000019, GO:0051431=GO_REF:0000002, GO:0007586=GO_REF:0000002, GO:0071456=GO_REF:0000019, GO:0005615=GO_REF:0000002, GO:0009749=GO_REF:0000019, GO:0042594=GO_REF:0000019, GO:0005179=GO_REF:0000037, GO:0031669=GO_REF:0000019, GO:0043196=GO_REF:0000019, GO:0032024=GO_REF:0000019, GO:0043679=GO_REF:0000019, GO:0007189=GO_REF:0000019} Q969E3 Urocortin-3 protein 20130413 {GO:0035902=IEA, GO:0051412=IEA, GO:0051431=IEA, GO:0007586=IEA, GO:0071456=IEA, GO:0005615=IEA, GO:0009749=IEA, GO:0042594=IEA, GO:0005179=IEA, GO:0031669=IEA, GO:0043196=IEA, GO:0032024=IEA, GO:0043679=IEA, GO:0007189=IEA} adenylate cyclase-activating G-protein coupled receptor signaling pathway, cellular response to hypoxia, cellular response to nutrient levels, digestion, positive regulation of insulin secretion, response to corticosterone stimulus, response to glucose stimulus, response to immobilization stress, response to starvation axon terminus, extracellular space, varicosity corticotropin-releasing hormone receptor 2 binding, hormone activity Human Ensembl:ENSRNOP00000023887 UCP1 Reactome UniProtKB {GO:0022904=Reactome:REACT_6305, GO:0005739=PMID:9054939, GO:0006357=GO_REF:0000019, GO:0050873=GO_REF:0000024, GO:0017077=GO_REF:0000019, GO:0005743=Reactome:REACT_6312, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0006839=GO_REF:0000002, GO:0015992=Reactome:REACT_6341} P25874 Mitochondrial brown fat uncoupling protein 1 protein 20130301 {GO:0022904=TAS, GO:0005739=IDA, GO:0006357=IEA, GO:0050873=ISS, GO:0017077=IEA, GO:0005743=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0006839=IEA, GO:0015992=TAS} brown fat cell differentiation, mitochondrial transport, proton transport, regulation of transcription from RNA polymerase II promoter, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane, mitochondrion oxidative phosphorylation uncoupler activity Human UCP2 Reactome UniProtKB {GO:0001666=GO_REF:0000019, GO:0032869=GO_REF:0000019, GO:0031966=GO_REF:0000002, GO:0005743=Reactome:REACT_6312, GO:0044281=Reactome:REACT_111217, GO:0009749=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0022904=Reactome:REACT_6305, GO:0070542=GO_REF:0000019, GO:0006810=PMID:9196039, GO:0000303=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0006839=GO_REF:0000019, GO:0015992=Reactome:REACT_6341} P55851 Mitochondrial uncoupling protein 2 protein 20130301 {GO:0001666=IEA, GO:0032869=IEA, GO:0031966=IEA, GO:0005743=TAS, GO:0044281=TAS, GO:0009749=IEA, GO:0005739=IEA, GO:0022904=TAS, GO:0070542=IEA, GO:0006810=NAS, GO:0000303=IEA, GO:0016021=IEA, GO:0006839=IEA, GO:0015992=TAS} cellular response to insulin stimulus, mitochondrial transport, proton transport, respiratory electron transport chain, response to fatty acid, response to glucose stimulus, response to hypoxia, response to superoxide, small molecule metabolic process, transport integral to membrane, mitochondrial inner membrane, mitochondrial membrane, mitochondrion Human UCP3 Reactome UniProtKB {GO:0006629=PMID:10935638, GO:0005215=PMID:9196039, GO:0001666=GO_REF:0000019, GO:0014823=GO_REF:0000019, GO:0032868=GO_REF:0000019, GO:0031966=GO_REF:0000002, GO:0007585=PMID:9180264, GO:0007584=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0009409=GO_REF:0000019, GO:0005743=Reactome:REACT_6312, GO:0051384=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0032870=GO_REF:0000019, GO:0022904=Reactome:REACT_6305, GO:0005739=PMID:9180264, GO:0017077=GO_REF:0000019, GO:0006631=GO_REF:0000019, GO:0000303=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0006839=GO_REF:0000002, GO:0015992=Reactome:REACT_6341} P55916 Mitochondrial uncoupling protein 3 protein 20130301 {GO:0006629=TAS, GO:0005215=TAS, GO:0001666=IEA, GO:0014823=IEA, GO:0032868=IEA, GO:0031966=IEA, GO:0007585=TAS, GO:0007584=IEA, GO:0007568=IEA, GO:0009409=IEA, GO:0005743=TAS, GO:0051384=IEA, GO:0044281=TAS, GO:0032870=IEA, GO:0022904=TAS, GO:0005739=TAS, GO:0017077=IEA, GO:0006631=IEA, GO:0000303=IEA, GO:0016021=IEA, GO:0006839=IEA, GO:0015992=TAS} aging, cellular response to hormone stimulus, fatty acid metabolic process, lipid metabolic process, mitochondrial transport, proton transport, respiratory electron transport chain, respiratory gaseous exchange, response to activity, response to cold, response to glucocorticoid stimulus, response to hypoxia, response to insulin stimulus, response to nutrient, response to superoxide, small molecule metabolic process integral to membrane, mitochondrial inner membrane, mitochondrial membrane, mitochondrion oxidative phosphorylation uncoupler activity, transporter activity Human UEVLD InterPro UniProtKB {GO:0044262=GO_REF:0000002, GO:0015031=GO_REF:0000002, GO:0006464=GO_REF:0000002, GO:0016616=GO_REF:0000002} Q8IX04 Ubiquitin-conjugating enzyme E2 variant 3 protein 20130413 {GO:0044262=IEA, GO:0015031=IEA, GO:0006464=IEA, GO:0016616=IEA} cellular carbohydrate metabolic process, cellular protein modification process, protein transport oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Human InterPro:IPR001557 UFC1 UniProtKB UniProtKB {GO:0005515=PMID:20018847, GO:0071568=PMID:15071506, GO:0071569=PMID:15071506} Q9Y3C8 Ubiquitin-fold modifier-conjugating enzyme 1 protein 20100204 {GO:0005515=IPI, GO:0071568=IDA, GO:0071569=IDA} protein ufmylation UFM1 conjugating enzyme activity, protein binding Human UFD1L PINC UniProtKB {GO:0005515=PMID:17681147, GO:0006511=PMID:9063746, GO:0001501=PMID:10024240, GO:0005737=GO_REF:0000019, GO:0004843=PMID:9063746, GO:0005102=GO_REF:0000019, GO:0043161=GO_REF:0000041, GO:0005634=GO_REF:0000039, GO:0032403=GO_REF:0000019, GO:0005829=GO_REF:0000039} Q92890 Ubiquitin fusion degradation protein 1 homolog protein 20030904 {GO:0005515=IPI, GO:0006511=TAS, GO:0001501=TAS, GO:0005737=IEA, GO:0004843=TAS, GO:0005102=IEA, GO:0043161=IEA, GO:0005634=IEA, GO:0032403=IEA, GO:0005829=IEA} proteasomal ubiquitin-dependent protein catabolic process, skeletal system development, ubiquitin-dependent protein catabolic process cytoplasm, cytosol, nucleus protein binding, protein complex binding, receptor binding, ubiquitin-specific protease activity Human UFL1 HPA UniProtKB {GO:0005515=PMID:20018847, GO:0071568=PMID:20018847, GO:0005737=PMID:20164180, GO:0005783=GO_REF:0000052, GO:0071569=PMID:20018847, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0032088=PMID:20164180, GO:0031397=PMID:20164180} O94874 E3 UFM1-protein ligase 1 protein 20101115 {GO:0005515=IPI, GO:0071568=IDA, GO:0005737=IDA, GO:0005783=IDA, GO:0071569=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0032088=IMP, GO:0031397=IDA} negative regulation of NF-kappaB transcription factor activity, negative regulation of protein ubiquitination, protein ufmylation cytoplasm, endoplasmic reticulum, nucleolus, nucleus UFM1 conjugating enzyme activity, protein binding Human UFM1 UniProtKB UniProtKB {GO:0005737=PMID:15071506, GO:0071569=PMID:15071506, GO:0005634=PMID:15071506} P61960 Ubiquitin-fold modifier 1 protein 20100204 {GO:0005737=IDA, GO:0071569=IDA, GO:0005634=IDA} protein ufmylation cytoplasm, nucleus Human UFSP2 UniProtKB UniProtKB {GO:0019783=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0005783=GO_REF:0000024, GO:0006508=GO_REF:0000037, GO:0005634=GO_REF:0000024, GO:0016790=GO_REF:0000019} Q9NUQ7 Ufm1-specific protease 2 protein 20110214 {GO:0019783=ISS, GO:0005737=ISS, GO:0005783=ISS, GO:0006508=IEA, GO:0005634=ISS, GO:0016790=IEA} proteolysis cytoplasm, endoplasmic reticulum, nucleus small conjugating protein-specific protease activity, thiolester hydrolase activity Human UniProtKB:Q99K23 UGCG Reactome UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0008120=GO_REF:0000003, GO:0006687=Reactome:REACT_116105, GO:0000139=Reactome:REACT_115635, GO:0008544=PMID:9545298, GO:0016020=PMID:8643456, GO:0006688=PMID:8643456, GO:0006679=PMID:8643456, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037} Q16739 Ceramide glucosyltransferase protein 20130301 {GO:0006665=TAS, GO:0008120=IEA, GO:0006687=TAS, GO:0000139=TAS, GO:0008544=TAS, GO:0016020=TAS, GO:0006688=TAS, GO:0006679=TAS, GO:0044281=TAS, GO:0016021=IEA} epidermis development, glucosylceramide biosynthetic process, glycosphingolipid biosynthetic process, glycosphingolipid metabolic process, small molecule metabolic process, sphingolipid metabolic process Golgi membrane, integral to membrane, membrane ceramide glucosyltransferase activity Human UGDH Reactome UniProtKB {GO:0003979=Reactome:REACT_6876, GO:0006805=Reactome:REACT_13433, GO:0051287=GO_REF:0000002, GO:0009055=PMID:9737970, GO:0006065=Reactome:REACT_6737, GO:0044281=Reactome:REACT_111217, GO:0006011=PMID:9737970, GO:0006024=PMID:9737970, GO:0001702=GO_REF:0000019, GO:0005829=Reactome:REACT_6876, GO:0016616=GO_REF:0000002} O60701 UDP-glucose 6-dehydrogenase protein 20080429 {GO:0003979=TAS, GO:0006805=TAS, GO:0051287=IEA, GO:0009055=TAS, GO:0006065=TAS, GO:0044281=TAS, GO:0006011=TAS, GO:0006024=TAS, GO:0001702=IEA, GO:0005829=TAS, GO:0016616=IEA} UDP-glucose metabolic process, UDP-glucuronate biosynthetic process, gastrulation with mouth forming second, glycosaminoglycan biosynthetic process, small molecule metabolic process, xenobiotic metabolic process cytosol NAD binding, UDP-glucose 6-dehydrogenase activity, electron carrier activity, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Human UGGT1 Reactome UniProtKB {GO:0005793=GO_REF:0000024, GO:0006457=Reactome:REACT_23878, GO:0005783=PMID:10694380, GO:0005788=Reactome:REACT_25264, GO:0051084=PMID:10694380, GO:0006486=GO_REF:0000002, GO:0003980=PMID:10694380, GO:0051082=PMID:10694380, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q9NYU2 UDP-glucose:glycoprotein glucosyltransferase 1 protein 20130301 {GO:0005793=ISS, GO:0006457=TAS, GO:0005783=IDA, GO:0005788=TAS, GO:0051084=TAS, GO:0006486=IEA, GO:0003980=IDA, GO:0051082=IDA, GO:0044267=TAS, GO:0043687=TAS, GO:0018279=TAS} 'de novo' posttranslational protein folding, cellular protein metabolic process, post-translational protein modification, protein N-linked glycosylation via asparagine, protein folding, protein glycosylation endoplasmic reticulum, endoplasmic reticulum lumen, endoplasmic reticulum-Golgi intermediate compartment UDP-glucose:glycoprotein glucosyltransferase activity, unfolded protein binding Human UGGT2 GOC UniProtKB {GO:0005793=GO_REF:0000039, GO:0006457=Reactome:REACT_23878, GO:0005788=Reactome:REACT_25264, GO:0006486=GO_REF:0000002, GO:0003980=GO_REF:0000024, GO:0044267=Reactome:REACT_17015, GO:0097359=GO_REF:0000024, GO:0043687=Reactome:REACT_22161, GO:0018279=Reactome:REACT_22426} Q9NYU1 UDP-glucose:glycoprotein glucosyltransferase 2 protein 20130413 {GO:0005793=IEA, GO:0006457=TAS, GO:0005788=TAS, GO:0006486=IEA, GO:0003980=ISS, GO:0044267=TAS, GO:0097359=ISS, GO:0043687=TAS, GO:0018279=TAS} UDP-glucosylation, cellular protein metabolic process, post-translational protein modification, protein N-linked glycosylation via asparagine, protein folding, protein glycosylation endoplasmic reticulum lumen, endoplasmic reticulum-Golgi intermediate compartment UDP-glucose:glycoprotein glucosyltransferase activity Human UniProtKB:Q9JLA3 UGP2 IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0006805=Reactome:REACT_13433, GO:0005975=Reactome:REACT_474, GO:0005978=Reactome:REACT_1736, GO:0016779=GO_REF:0000002, GO:0003983=Reactome:REACT_86, GO:0006065=Reactome:REACT_6737, GO:0044281=Reactome:REACT_111217, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_86, GO:0016310=GO_REF:0000029, GO:0005737=GO_REF:0000029, GO:0006006=Reactome:REACT_723, GO:0006011=PMID:8631325} Q16851 UTP--glucose-1-phosphate uridylyltransferase protein 20130415 {GO:0005515=IPI, GO:0006805=TAS, GO:0005975=TAS, GO:0005978=TAS, GO:0016779=IEA, GO:0003983=EXP, GO:0006065=TAS, GO:0044281=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0016310=NAS, GO:0005737=NAS, GO:0006006=TAS, GO:0006011=TAS} UDP-glucose metabolic process, UDP-glucuronate biosynthetic process, carbohydrate metabolic process, glucose metabolic process, glycogen biosynthetic process, phosphorylation, small molecule metabolic process, xenobiotic metabolic process cytoplasm, cytosol UTP:glucose-1-phosphate uridylyltransferase activity, metal ion binding, nucleotidyltransferase activity, protein binding Human UniProtKB:P62993 UGT1A1 BioGRID UDP glucuronosyltransferase 1 family, polypeptide A1 protein UGT2B10 PINC UniProtKB {GO:0006629=PMID:8333863, GO:0016758=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0015020=GO_REF:0000003, GO:0016021=GO_REF:0000037} P36537 UDP-glucuronosyltransferase 2B10 protein 20030904 {GO:0006629=TAS, GO:0016758=IEA, GO:0005789=IEA, GO:0015020=IEA, GO:0016021=IEA} lipid metabolic process endoplasmic reticulum membrane, integral to membrane glucuronosyltransferase activity, transferase activity, transferring hexosyl groups Human UGT2B11 PINC UniProtKB {GO:0008210=PMID:8333863, GO:0006805=PMID:8333863, GO:0005789=GO_REF:0000039, GO:0015020=GO_REF:0000003, GO:0016021=GO_REF:0000037} O75310 UDP-glucuronosyltransferase 2B11 protein 20030904 {GO:0008210=TAS, GO:0006805=TAS, GO:0005789=IEA, GO:0015020=IEA, GO:0016021=IEA} estrogen metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane, integral to membrane glucuronosyltransferase activity Human UGT2B15 BHF-UCL UniProtKB {GO:0006805=PMID:7835232, GO:0052695=PMID:20056724, GO:0001972=PMID:20308471, GO:0005789=GO_REF:0000039, GO:0015020=PMID:20056724, GO:0016021=GO_REF:0000037, GO:0008202=PMID:7835232} P54855 UDP-glucuronosyltransferase 2B15 protein 20100726 {GO:0006805=TAS, GO:0052695=IDA, GO:0001972=IDA, GO:0005789=IEA, GO:0015020=IDA, GO:0016021=IEA, GO:0008202=TAS} cellular glucuronidation, steroid metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane, integral to membrane glucuronosyltransferase activity, retinoic acid binding NOT Human UGT2B17 BHF-UCL UniProtKB {GO:0016020=PMID:8798464, GO:0001972=PMID:20308471, GO:0005789=GO_REF:0000039, GO:0015020=GO_REF:0000003, GO:0016021=GO_REF:0000037, GO:0008202=PMID:8798464} O75795 UDP-glucuronosyltransferase 2B17 protein 20100726 {GO:0016020=TAS, GO:0001972=IDA, GO:0005789=IEA, GO:0015020=IEA, GO:0016021=IEA, GO:0008202=TAS} steroid metabolic process endoplasmic reticulum membrane, integral to membrane, membrane glucuronosyltransferase activity, retinoic acid binding NOT Human UGT2B28 UniProtKB UniProtKB {GO:0006805=PMID:11300766, GO:0005783=PMID:11300766, GO:0008152=PMID:11300766, GO:0005789=GO_REF:0000039, GO:0015020=GO_REF:0000003, GO:0016021=GO_REF:0000037} Q9BY64 UDP-glucuronosyltransferase 2B28 protein 20011004 {GO:0006805=IDA, GO:0005783=IDA, GO:0008152=IDA, GO:0005789=IEA, GO:0015020=IEA, GO:0016021=IEA} metabolic process, xenobiotic metabolic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane glucuronosyltransferase activity Human UGT2B4 BHF-UCL UniProtKB {GO:0006805=PMID:8333863, GO:0052695=PMID:20056724, GO:0016758=GO_REF:0000002, GO:0001972=PMID:20308471, GO:0008152=PMID:8333863, GO:0005789=GO_REF:0000039, GO:0015020=PMID:20056724, GO:0006711=PMID:8333863, GO:0016021=GO_REF:0000037, GO:0043231=GO_REF:0000029} P06133 UDP-glucuronosyltransferase 2B4 protein 20100726 {GO:0006805=IDA, GO:0052695=IDA, GO:0016758=IEA, GO:0001972=IDA, GO:0008152=IDA, GO:0005789=IEA, GO:0015020=IDA, GO:0006711=IDA, GO:0016021=IEA, GO:0043231=NAS} cellular glucuronidation, estrogen catabolic process, metabolic process, xenobiotic metabolic process endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle glucuronosyltransferase activity, retinoic acid binding, transferase activity, transferring hexosyl groups NOT Human UGT2B7 BHF-UCL UniProtKB {GO:0006629=PMID:2159463, GO:0016020=PMID:2159463, GO:0052695=PMID:20056724, GO:0016758=GO_REF:0000002, GO:0008209=PMID:17442341, GO:0001972=PMID:20308471, GO:0005789=GO_REF:0000039, GO:0015020=PMID:20056724, GO:0016021=GO_REF:0000037} P16662 UDP-glucuronosyltransferase 2B7 protein 20100726 {GO:0006629=TAS, GO:0016020=TAS, GO:0052695=IDA, GO:0016758=IEA, GO:0008209=IDA, GO:0001972=IDA, GO:0005789=IEA, GO:0015020=IDA, GO:0016021=IEA} androgen metabolic process, cellular glucuronidation, lipid metabolic process endoplasmic reticulum membrane, integral to membrane, membrane glucuronosyltransferase activity, retinoic acid binding, transferase activity, transferring hexosyl groups NOT Human UGT8 PINC UniProtKB {GO:0006682=GO_REF:0000041, GO:0003851=GO_REF:0000003, GO:0002175=GO_REF:0000019, GO:0030913=GO_REF:0000019, GO:0048812=GO_REF:0000019, GO:0008489=GO_REF:0000019, GO:0007422=PMID:8661025, GO:0007010=GO_REF:0000019, GO:0008088=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0007417=PMID:8661025} Q16880 2-hydroxyacylsphingosine 1-beta-galactosyltransferase protein 20030904 {GO:0006682=IEA, GO:0003851=IEA, GO:0002175=IEA, GO:0030913=IEA, GO:0048812=IEA, GO:0008489=IEA, GO:0007422=TAS, GO:0007010=IEA, GO:0008088=IEA, GO:0016021=IEA, GO:0007417=TAS} axon cargo transport, central nervous system development, cytoskeleton organization, galactosylceramide biosynthetic process, neuron projection morphogenesis, paranodal junction assembly, peripheral nervous system development, protein localization to paranode region of axon integral to membrane 2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity, UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity Human UHMK1 BHF-UCL UniProtKB {GO:0005515=PMID:12093740, GO:0030424=GO_REF:0000024, GO:0071598=GO_REF:0000024, GO:0003723=GO_REF:0000037, GO:0005634=PMID:12093740, GO:0032839=GO_REF:0000024, GO:0005524=PMID:12093740, GO:0031175=GO_REF:0000024, GO:0046777=PMID:12093740, GO:0018105=PMID:12093740, GO:0004674=PMID:12093740, GO:0043021=GO_REF:0000024, GO:0007050=PMID:12093740, GO:0045948=GO_REF:0000024, GO:0019899=GO_REF:0000019, GO:0046825=PMID:12093740, GO:0016740=PMID:12093740} Q8TAS1 Serine/threonine-protein kinase Kist protein 20100209 {GO:0005515=IPI, GO:0030424=ISS, GO:0071598=ISS, GO:0003723=IEA, GO:0005634=IDA, GO:0032839=ISS, GO:0005524=IC, GO:0031175=ISS, GO:0046777=IDA, GO:0018105=IDA, GO:0004674=IDA, GO:0043021=ISS, GO:0007050=IMP, GO:0045948=ISS, GO:0019899=IEA, GO:0046825=IDA, GO:0016740=IC} cell cycle arrest, neuron projection development, peptidyl-serine phosphorylation, positive regulation of translational initiation, protein autophosphorylation, regulation of protein export from nucleus axon, dendrite cytoplasm, neuronal ribonucleoprotein granule, nucleus ATP binding, RNA binding, enzyme binding, protein binding, protein serine/threonine kinase activity, ribonucleoprotein complex binding, transferase activity Human UniProtKB:P97343 UHRF1 HPA UniProtKB {GO:0000792=PMID:21777816, GO:0005515=PMID:15361834, GO:0000987=PMID:10646863, GO:2000373=PMID:10646863, GO:0004842=GO_REF:0000024, GO:0008327=PMID:15361834, GO:0000790=GO_REF:0000024, GO:0000791=PMID:21777816, GO:0003700=PMID:1868030, GO:0008283=PMID:15361834, GO:0005657=PMID:17673620, GO:0005634=GO_REF:0000052, GO:0035064=PMID:21489993, GO:0016363=GO_REF:0000024, GO:0042802=GO_REF:0000024, GO:0042393=PMID:21777816, GO:0010216=PMID:17673620, GO:0042787=PMID:22945642, GO:0045944=PMID:10646863, GO:0016574=PMID:17967883, GO:0031493=GO_REF:0000024, GO:0000122=PMID:21777816, GO:0006351=GO_REF:0000037, GO:0051865=PMID:17967883, GO:0032270=PMID:10646863, GO:0007049=GO_REF:0000037, GO:0006281=GO_REF:0000037, GO:0008270=PMID:21777816, GO:0010390=GO_REF:0000024, GO:0044729=PMID:17673620} Q96T88 E3 ubiquitin-protein ligase UHRF1 protein 20120912 {GO:0000792=IDA, GO:0005515=IPI, GO:0000987=IDA, GO:2000373=IC, GO:0004842=ISS, GO:0008327=IDA, GO:0000790=ISS, GO:0000791=IDA, GO:0003700=TAS, GO:0008283=IEP, GO:0005657=IDA, GO:0005634=IDA, GO:0035064=IDA, GO:0016363=ISS, GO:0042802=ISS, GO:0042393=IDA, GO:0010216=IMP, GO:0042787=IDA, GO:0045944=IC, GO:0016574=IDA, GO:0031493=ISS, GO:0000122=IDA, GO:0006351=IEA, GO:0051865=IDA, GO:0032270=IDA, GO:0007049=IEA, GO:0006281=IEA, GO:0008270=IDA, GO:0010390=ISS, GO:0044729=IDA} DNA repair, cell cycle, cell proliferation, histone monoubiquitination, histone ubiquitination, maintenance of DNA methylation, negative regulation of transcription from RNA polymerase II promoter, positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity, positive regulation of cellular protein metabolic process, positive regulation of transcription from RNA polymerase II promoter, protein autoubiquitination, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, transcription, DNA-dependent euchromatin, heterochromatin, nuclear chromatin, nuclear matrix, nucleus, replication fork core promoter proximal region sequence-specific DNA binding, hemi-methylated DNA-binding, histone binding, identical protein binding, methyl-CpG binding, methylated histone residue binding, nucleosomal histone binding, protein binding, sequence-specific DNA binding transcription factor activity, ubiquitin-protein ligase activity, zinc ion binding Human UHRF1BP1 BHF-UCL UniProtKB {GO:0005515=PMID:15361834, GO:0042826=PMID:15361834, GO:0042802=PMID:15361834} Q6BDS2 UHRF1-binding protein 1 protein 20110803 {GO:0005515=IPI, GO:0042826=IPI, GO:0042802=IPI} histone deacetylase binding, identical protein binding, protein binding Human UniProtKB:Q13547 UHRF1BP1L null null {} null null null null {} null null null UHRF2 HPA UniProtKB {GO:0005515=PMID:21952639, GO:0006511=PMID:14741369, GO:0004842=PMID:14741369, GO:0016567=PMID:14741369, GO:0008283=PMID:12176013, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0071158=PMID:15178429, GO:0030154=PMID:12176013, GO:0051865=PMID:14741369, GO:0042393=GO_REF:0000024, GO:0007049=GO_REF:0000037, GO:0005720=GO_REF:0000024, GO:0051726=PMID:14741369, GO:0008270=GO_REF:0000002} Q96PU4 E3 ubiquitin-protein ligase UHRF2 protein 20101115 {GO:0005515=IPI, GO:0006511=IDA, GO:0004842=IDA, GO:0016567=IDA, GO:0008283=IEP, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0071158=IDA, GO:0030154=IEP, GO:0051865=IDA, GO:0042393=ISS, GO:0007049=IEA, GO:0005720=ISS, GO:0051726=TAS, GO:0008270=IEA} cell cycle, cell differentiation, cell proliferation, positive regulation of cell cycle arrest, protein autoubiquitination, protein ubiquitination, regulation of cell cycle, ubiquitin-dependent protein catabolic process nuclear heterochromatin, nucleolus, nucleus DNA binding, histone binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding NOT Human UIMC1 HPA UniProtKB {GO:0005515=PMID:19615732, GO:0031572=PMID:17525340, GO:0005634=GO_REF:0000052, GO:0045739=PMID:17525342, GO:0006351=GO_REF:0000037, GO:0006302=PMID:19261748, GO:0046965=GO_REF:0000019, GO:0070531=PMID:17525341, GO:0042393=PMID:17525342, GO:0010212=PMID:17525342, GO:0070537=PMID:19202061, GO:0045892=PMID:12080054, GO:0070530=PMID:22742833} Q96RL1 BRCA1-A complex subunit RAP80 protein 20110516 {GO:0005515=IPI, GO:0031572=IMP, GO:0005634=IDA, GO:0045739=IMP, GO:0006351=IEA, GO:0006302=IMP, GO:0046965=IEA, GO:0070531=IDA, GO:0042393=IDA, GO:0010212=IMP, GO:0070537=IMP, GO:0045892=IDA, GO:0070530=IDA} G2 DNA damage checkpoint, double-strand break repair, histone H2A K63-linked deubiquitination, negative regulation of transcription, DNA-dependent, positive regulation of DNA repair, response to ionizing radiation, transcription, DNA-dependent BRCA1-A complex, nucleus K63-linked polyubiquitin binding, histone binding, protein binding, retinoid X receptor binding Human ULBP1 Reactome UniProtKB {GO:0005886=Reactome:REACT_11178, GO:0030101=PMID:11239445, GO:0005783=GO_REF:0000039, GO:0019882=GO_REF:0000002, GO:0042267=PMID:11239445, GO:0046703=PMID:11239445, GO:0042612=GO_REF:0000002, GO:0050776=Reactome:REACT_11152, GO:0046658=PMID:11239445} Q9BZM6 NKG2D ligand 1 protein 20130228 {GO:0005886=TAS, GO:0030101=IDA, GO:0005783=IEA, GO:0019882=IEA, GO:0042267=IDA, GO:0046703=IDA, GO:0042612=IEA, GO:0050776=TAS, GO:0046658=IDA} antigen processing and presentation, natural killer cell activation, natural killer cell mediated cytotoxicity, regulation of immune response MHC class I protein complex, anchored to plasma membrane, endoplasmic reticulum, plasma membrane natural killer cell lectin-like receptor binding Human ULBP2 BHF-UCL UniProtKB {GO:0009986=PMID:18676862, GO:0030101=PMID:11239445, GO:0019882=GO_REF:0000002, GO:0042267=PMID:11239445, GO:0046703=PMID:11239445, GO:0042612=GO_REF:0000002, GO:0005615=PMID:18676862, GO:0046658=PMID:11239445} Q9BZM5 NKG2D ligand 2 protein 20081119 {GO:0009986=IDA, GO:0030101=IDA, GO:0019882=IEA, GO:0042267=IDA, GO:0046703=IDA, GO:0042612=IEA, GO:0005615=IDA, GO:0046658=IDA} antigen processing and presentation, natural killer cell activation, natural killer cell mediated cytotoxicity MHC class I protein complex, anchored to plasma membrane, cell surface, extracellular space natural killer cell lectin-like receptor binding Human ULBP3 Reactome UniProtKB {GO:0005886=Reactome:REACT_11178, GO:0030101=PMID:11239445, GO:0019882=GO_REF:0000002, GO:0042267=PMID:11239445, GO:0046703=PMID:11239445, GO:0019048=GO_REF:0000037, GO:0042612=GO_REF:0000002, GO:0050776=Reactome:REACT_11152, GO:0046658=PMID:11239445} Q9BZM4 NKG2D ligand 3 protein 20130228 {GO:0005886=TAS, GO:0030101=IDA, GO:0019882=IEA, GO:0042267=IDA, GO:0046703=IDA, GO:0019048=IEA, GO:0042612=IEA, GO:0050776=TAS, GO:0046658=IDA} antigen processing and presentation, natural killer cell activation, natural killer cell mediated cytotoxicity, regulation of immune response, virus-host interaction MHC class I protein complex, anchored to plasma membrane, plasma membrane natural killer cell lectin-like receptor binding Human ULK1 BHF-UCL UniProtKB {GO:0005515=PMID:22354037, GO:0043005=GO_REF:0000019, GO:0031102=GO_REF:0000019, GO:0007265=GO_REF:0000019, GO:0048675=GO_REF:0000019, GO:0032403=PMID:19211835, GO:0031175=PMID:18007665, GO:0048671=GO_REF:0000019, GO:0005829=PMID:11146101, GO:0031623=GO_REF:0000019, GO:0021707=GO_REF:0000019, GO:0005737=PMID:9693035, GO:0042594=GO_REF:0000024, GO:0046777=PMID:18936157, GO:0070969=PMID:19211835, GO:0008104=PMID:16940348, GO:0031669=GO_REF:0000024, GO:0043025=GO_REF:0000019, GO:0000045=GO_REF:0000019, GO:0030659=GO_REF:0000019, GO:0016239=PMID:22354037, GO:0017137=PMID:22613832, GO:0021933=GO_REF:0000019, GO:0005776=PMID:17595159, GO:0019901=GO_REF:0000019, GO:0051386=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0034045=PMID:18936157, GO:0004674=PMID:18936157, GO:0010506=PMID:18936157, GO:0006468=PMID:9693035, GO:0010508=GO_REF:0000024} O75385 Serine/threonine-protein kinase ULK1 protein 20120531 {GO:0005515=IPI, GO:0043005=IEA, GO:0031102=IEA, GO:0007265=IEA, GO:0048675=IEA, GO:0032403=IPI, GO:0031175=IMP, GO:0048671=IEA, GO:0005829=IDA, GO:0031623=IEA, GO:0021707=IEA, GO:0005737=NAS, GO:0042594=ISS, GO:0046777=IDA, GO:0070969=IPI, GO:0008104=IMP, GO:0031669=ISS, GO:0043025=IEA, GO:0000045=IEA, GO:0030659=IEA, GO:0016239=IMP, GO:0017137=IPI, GO:0021933=IEA, GO:0005776=IDA, GO:0019901=IEA, GO:0051386=IEA, GO:0005524=IEA, GO:0034045=IDA, GO:0004674=IDA, GO:0010506=IDA, GO:0006468=NAS, GO:0010508=ISS} Ras protein signal transduction, autophagic vacuole assembly, axon extension, cellular response to nutrient levels, cerebellar granule cell differentiation, negative regulation of collateral sprouting, neuron projection development, neuron projection regeneration, positive regulation of autophagy, positive regulation of macroautophagy, protein autophosphorylation, protein localization, protein phosphorylation, radial glia guided migration of cerebellar granule cell, receptor internalization, regulation of autophagy, regulation of neurotrophin TRK receptor signaling pathway, response to starvation ULK1-ATG13-FIP200 complex, autophagic vacuole, cytoplasm, cytoplasmic vesicle membrane, cytosol, neuron projection, neuronal cell body, pre-autophagosomal structure membrane ATP binding, Rab GTPase binding, protein binding, protein complex binding, protein kinase binding, protein serine/threonine kinase activity Human UniProtKB:Q9Y250 ULK2 UniProtKB UniProtKB {GO:0005515=PMID:18936157, GO:0007165=GO_REF:0000002, GO:0034045=PMID:18936157, GO:0042594=GO_REF:0000024, GO:0046777=PMID:18936157, GO:0004674=PMID:18936157, GO:0006914=GO_REF:0000037, GO:0010506=PMID:18936157, GO:0048675=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0030659=GO_REF:0000039, GO:0048671=GO_REF:0000019} Q8IYT8 Serine/threonine-protein kinase ULK2 protein 20110818 {GO:0005515=IPI, GO:0007165=IEA, GO:0034045=IDA, GO:0042594=ISS, GO:0046777=IDA, GO:0004674=IDA, GO:0006914=IEA, GO:0010506=IDA, GO:0048675=IEA, GO:0005524=IEA, GO:0030659=IEA, GO:0048671=IEA} autophagy, axon extension, negative regulation of collateral sprouting, protein autophosphorylation, regulation of autophagy, response to starvation, signal transduction cytoplasmic vesicle membrane, pre-autophagosomal structure membrane ATP binding, protein binding, protein serine/threonine kinase activity Human UniProtKB:Q9QY01 ULK3 UniProtKB UniProtKB {GO:0005515=PMID:20643644, GO:0045880=PMID:19878745, GO:0005737=PMID:19878745, GO:0046777=PMID:20643644, GO:0004672=GO_REF:0000002, GO:0004674=PMID:19878745, GO:0006914=PMID:19279323, GO:0045879=PMID:20643644, GO:0000407=PMID:19279323, GO:0005524=GO_REF:0000037, GO:0090398=PMID:19279323} Q6PHR2 Serine/threonine-protein kinase ULK3 protein 20110818 {GO:0005515=IPI, GO:0045880=IDA, GO:0005737=IDA, GO:0046777=IDA, GO:0004672=IEA, GO:0004674=IDA, GO:0006914=TAS, GO:0045879=IDA, GO:0000407=TAS, GO:0005524=IEA, GO:0090398=TAS} autophagy, cellular senescence, negative regulation of smoothened signaling pathway, positive regulation of smoothened signaling pathway, protein autophosphorylation cytoplasm, pre-autophagosomal structure ATP binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human ULK4 ENSEMBL UniProtKB {GO:0004672=GO_REF:0000002, GO:0003351=GO_REF:0000019, GO:0004674=GO_REF:0000037, GO:0060271=GO_REF:0000019, GO:0021591=GO_REF:0000019, GO:0005524=GO_REF:0000037} Q96C45 Serine/threonine-protein kinase ULK4 protein 20130413 {GO:0004672=IEA, GO:0003351=IEA, GO:0004674=IEA, GO:0060271=IEA, GO:0021591=IEA, GO:0005524=IEA} cilium morphogenesis, epithelial cilium movement, ventricular system development ATP binding, protein kinase activity, protein serine/threonine kinase activity Human Ensembl:ENSMUSP00000131342 UMOD MGI UniProtKB {GO:0048878=GO_REF:0000019, GO:0007588=GO_REF:0000019, GO:0060170=GO_REF:0000039, GO:0008285=PMID:2409603, GO:0005794=GO_REF:0000019, GO:0010033=GO_REF:0000019, GO:0072218=GO_REF:0000019, GO:0005509=GO_REF:0000002, GO:0045177=GO_REF:0000019, GO:0072233=GO_REF:0000019, GO:0005576=GO_REF:0000038, GO:0072372=PMID:20172860, GO:0031225=PMID:91065873, GO:0031410=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0072221=GO_REF:0000019, GO:0016323=PMID:7028707, GO:0006968=PMID:2409603, GO:0000922=PMID:20172860, GO:0016324=PMID:18025791, GO:0045121=GO_REF:0000019, GO:2000021=GO_REF:0000019, GO:0019898=PMID:7873609} P07911 Uromodulin protein 20090324 {GO:0048878=IEA, GO:0007588=IEA, GO:0060170=IEA, GO:0008285=TAS, GO:0005794=IEA, GO:0010033=IEA, GO:0072218=IEA, GO:0005509=IEA, GO:0045177=IEA, GO:0072233=IEA, GO:0005576=IEA, GO:0072372=IDA, GO:0031225=IDA, GO:0031410=IEA, GO:0005615=IEA, GO:0072221=IEA, GO:0016323=IDA, GO:0006968=TAS, GO:0000922=IDA, GO:0016324=IDA, GO:0045121=IEA, GO:2000021=IEA, GO:0019898=TAS} cellular defense response, chemical homeostasis, excretion, metanephric ascending thin limb development, metanephric distal convoluted tubule development, metanephric thick ascending limb development, negative regulation of cell proliferation, regulation of ion homeostasis, response to organic substance Golgi apparatus, anchored to membrane, apical part of cell, apical plasma membrane, basolateral plasma membrane, cilium membrane, cytoplasmic vesicle, extracellular region, extracellular space, extrinsic to membrane, membrane raft, primary cilium, spindle pole calcium ion binding Human UMPS Reactome UniProtKB {GO:0007565=GO_REF:0000019, GO:0044205=GO_REF:0000041, GO:0004588=Reactome:REACT_33, GO:0006222=PMID:6893554, GO:0055086=Reactome:REACT_1698, GO:0006221=GO_REF:0000002, GO:0005634=PMID:15890648, GO:0044281=Reactome:REACT_111217, GO:0004590=Reactome:REACT_225, GO:0035690=GO_REF:0000019, GO:0005829=Reactome:REACT_225, GO:0005737=PMID:15890648, GO:0046134=Reactome:REACT_21376, GO:0007595=GO_REF:0000019, GO:0009116=GO_REF:0000002, GO:0006207=GO_REF:0000002, GO:0006206=Reactome:REACT_957, GO:0016740=GO_REF:0000038} P11172 Uridine 5'-monophosphate synthase protein 20130213 {GO:0007565=IEA, GO:0044205=IEA, GO:0004588=TAS, GO:0006222=IDA, GO:0055086=TAS, GO:0006221=IEA, GO:0005634=IDA, GO:0044281=TAS, GO:0004590=TAS, GO:0035690=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0046134=TAS, GO:0007595=IEA, GO:0009116=IEA, GO:0006207=IEA, GO:0006206=TAS, GO:0016740=IEA} 'de novo' UMP biosynthetic process, 'de novo' pyrimidine nucleobase biosynthetic process, UMP biosynthetic process, cellular response to drug, female pregnancy, lactation, nucleobase-containing small molecule metabolic process, nucleoside metabolic process, pyrimidine nucleobase metabolic process, pyrimidine nucleoside biosynthetic process, pyrimidine nucleotide biosynthetic process, small molecule metabolic process cytoplasm, cytosol, nucleus orotate phosphoribosyltransferase activity, orotidine-5'-phosphate decarboxylase activity, transferase activity Human UNC119 UniProtKB UniProtKB {GO:0005515=PMID:22085962, GO:0005813=PMID:22085962, GO:0042953=PMID:22085962, GO:0007268=PMID:9538874, GO:0007602=PMID:9538874, GO:0007601=GO_REF:0000037, GO:0005829=PMID:9538874, GO:0008289=PMID:22085962} Q13432 Protein unc-119 homolog A protein 20120113 {GO:0005515=IPI, GO:0005813=IDA, GO:0042953=IDA, GO:0007268=TAS, GO:0007602=TAS, GO:0007601=IEA, GO:0005829=TAS, GO:0008289=IDA} lipoprotein transport, phototransduction, synaptic transmission, visual perception centrosome, cytosol lipid binding, protein binding Human UniProtKB:Q717R9 UNC119B UniProtKB UniProtKB {GO:0005515=PMID:22085962, GO:0042953=PMID:22085962, GO:0035869=PMID:22085962, GO:0060271=PMID:22085962, GO:0008289=PMID:22085962} A6NIH7 Protein unc-119 homolog B protein 20120113 {GO:0005515=IPI, GO:0042953=IDA, GO:0035869=IDA, GO:0060271=IMP, GO:0008289=IDA} cilium morphogenesis, lipoprotein transport ciliary transition zone lipid binding, protein binding Human UniProtKB:Q717R9 UNC13A UniProtKB UniProtKB {GO:0016081=GO_REF:0000019, GO:0016082=GO_REF:0000002, GO:0030054=GO_REF:0000037, GO:0031594=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0035249=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0050435=GO_REF:0000019, GO:0019992=GO_REF:0000019, GO:0060384=GO_REF:0000019, GO:0035556=GO_REF:0000002, GO:0042734=GO_REF:0000039, GO:0005737=GO_REF:0000039, GO:0007528=GO_REF:0000019, GO:0016188=GO_REF:0000019, GO:0001956=GO_REF:0000019, GO:0048172=GO_REF:0000019} Q9UPW8 Protein unc-13 homolog A protein 20130413 {GO:0016081=IEA, GO:0016082=IEA, GO:0030054=IEA, GO:0031594=IEA, GO:0005886=IEA, GO:0035249=IEA, GO:0046872=IEA, GO:0050435=IEA, GO:0019992=IEA, GO:0060384=IEA, GO:0035556=IEA, GO:0042734=IEA, GO:0005737=IEA, GO:0007528=IEA, GO:0016188=IEA, GO:0001956=IEA, GO:0048172=IEA} beta-amyloid metabolic process, innervation, intracellular signal transduction, neuromuscular junction development, positive regulation of neurotransmitter secretion, regulation of short-term neuronal synaptic plasticity, synaptic transmission, glutamatergic, synaptic vesicle docking involved in exocytosis, synaptic vesicle maturation, synaptic vesicle priming cell junction, cytoplasm, neuromuscular junction, plasma membrane, presynaptic membrane diacylglycerol binding, metal ion binding Human UniProtKB-SubCell:SL-0222 UNC13B PINC UniProtKB {GO:0007588=PMID:9607201, GO:0016081=GO_REF:0000019, GO:0005794=PMID:9607201, GO:0030054=GO_REF:0000037, GO:0016082=GO_REF:0000019, GO:0031594=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0035249=GO_REF:0000019, GO:0007268=GO_REF:0000002, GO:0006917=PMID:10233166, GO:0046872=GO_REF:0000037, GO:0019992=GO_REF:0000002, GO:0035556=GO_REF:0000002, GO:0060384=GO_REF:0000019, GO:0007165=PMID:9607201, GO:0005737=PMID:10233166, GO:0007528=GO_REF:0000019, GO:0004872=PMID:9607201, GO:0004871=PMID:9607201, GO:0048172=GO_REF:0000019} O14795 Protein unc-13 homolog B protein 20030904 {GO:0007588=TAS, GO:0016081=IEA, GO:0005794=TAS, GO:0030054=IEA, GO:0016082=IEA, GO:0031594=IEA, GO:0005886=IEA, GO:0035249=IEA, GO:0007268=IEA, GO:0006917=TAS, GO:0046872=IEA, GO:0019992=IEA, GO:0035556=IEA, GO:0060384=IEA, GO:0007165=TAS, GO:0005737=TAS, GO:0007528=IEA, GO:0004872=TAS, GO:0004871=TAS, GO:0048172=IEA} excretion, induction of apoptosis, innervation, intracellular signal transduction, neuromuscular junction development, regulation of short-term neuronal synaptic plasticity, signal transduction, synaptic transmission, synaptic transmission, glutamatergic, synaptic vesicle docking involved in exocytosis, synaptic vesicle priming Golgi apparatus, cell junction, cytoplasm, neuromuscular junction, plasma membrane diacylglycerol binding, metal ion binding, receptor activity, signal transducer activity Human UNC13D UniProtKB UniProtKB {GO:0006909=GO_REF:0000019, GO:0005515=PMID:15548590, GO:0043304=PMID:15548590, GO:0043320=GO_REF:0000019, GO:0005770=GO_REF:0000039, GO:0005764=PMID:15548590, GO:0045921=PMID:19966785, GO:0051607=GO_REF:0000019, GO:0016020=GO_REF:0000039, GO:0002432=GO_REF:0000019, GO:0002467=GO_REF:0000019, GO:0055037=GO_REF:0000039, GO:0070382=PMID:17237785} Q70J99 Protein unc-13 homolog D protein 20110803 {GO:0006909=IEA, GO:0005515=IPI, GO:0043304=IMP, GO:0043320=IEA, GO:0005770=IEA, GO:0005764=IDA, GO:0045921=IMP, GO:0051607=IEA, GO:0016020=IEA, GO:0002432=IEA, GO:0002467=IEA, GO:0055037=IEA, GO:0070382=IDA} defense response to virus, germinal center formation, granuloma formation, natural killer cell degranulation, phagocytosis, positive regulation of exocytosis, regulation of mast cell degranulation exocytic vesicle, late endosome, lysosome, membrane, recycling endosome protein binding Human UNC45A UniProtKB UniProtKB {GO:0048471=GO_REF:0000039, GO:0007517=GO_REF:0000037, GO:0061077=GO_REF:0000019, GO:0051879=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0030154=GO_REF:0000037} Q9H3U1 Protein unc-45 homolog A protein 20130413 {GO:0048471=IEA, GO:0007517=IEA, GO:0061077=IEA, GO:0051879=IEA, GO:0005634=IEA, GO:0030154=IEA} cell differentiation, chaperone-mediated protein folding, muscle organ development nucleus, perinuclear region of cytoplasm Hsp90 protein binding Human UniProtKB-SubCell:SL-0198 UNC45B UniProtKB UniProtKB {GO:0007517=GO_REF:0000037, GO:0061077=GO_REF:0000019, GO:0051879=GO_REF:0000019, GO:0030154=GO_REF:0000037, GO:0005829=GO_REF:0000039} Q8IWX7 Protein unc-45 homolog B protein 20130413 {GO:0007517=IEA, GO:0061077=IEA, GO:0051879=IEA, GO:0030154=IEA, GO:0005829=IEA} cell differentiation, chaperone-mediated protein folding, muscle organ development cytosol Hsp90 protein binding Human UniProtKB-SubCell:SL-0091 UNC50 UniProtKB UniProtKB {GO:0000139=GO_REF:0000039, GO:0003723=GO_REF:0000019, GO:0005637=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0007166=GO_REF:0000019} Q53HI1 Protein unc-50 homolog protein 20130413 {GO:0000139=IEA, GO:0003723=IEA, GO:0005637=IEA, GO:0016021=IEA, GO:0015031=IEA, GO:0007166=IEA} cell surface receptor signaling pathway, protein transport Golgi membrane, integral to membrane, nuclear inner membrane RNA binding Human UniProtKB-SubCell:SL-0179 UNC5A Reactome UniProtKB {GO:0007165=GO_REF:0000002, GO:0005886=Reactome:REACT_22282, GO:0007411=Reactome:REACT_18266, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0016021=GO_REF:0000037} Q6ZN44 Netrin receptor UNC5A protein 20100520 {GO:0007165=IEA, GO:0005886=TAS, GO:0007411=TAS, GO:0006915=TAS, GO:0042981=TAS, GO:0016021=IEA} apoptotic process, axon guidance, regulation of apoptotic process, signal transduction integral to membrane, plasma membrane Human UNC5B IntAct UniProtKB {GO:0005515=PMID:18469807, GO:0007165=GO_REF:0000002, GO:0007411=Reactome:REACT_18266, GO:2001240=PMID:18469807, GO:0006915=Reactome:REACT_578, GO:0042981=Reactome:REACT_13648, GO:0016021=GO_REF:0000037} Q8IZJ1 Netrin receptor UNC5B protein 20130415 {GO:0005515=IPI, GO:0007165=IEA, GO:0007411=TAS, GO:2001240=IMP, GO:0006915=TAS, GO:0042981=TAS, GO:0016021=IEA} apoptotic process, axon guidance, negative regulation of extrinsic apoptotic signaling pathway in absence of ligand, regulation of apoptotic process, signal transduction integral to membrane protein binding Human UniProtKB:Q8CGU4 UNC5C Reactome UniProtKB {GO:0030334=GO_REF:0000019, GO:0005042=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0007411=Reactome:REACT_18266, GO:0007420=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0016021=GO_REF:0000037} O95185 Netrin receptor UNC5C protein 20070514 {GO:0030334=IEA, GO:0005042=IEA, GO:0043065=IEA, GO:0005886=IEA, GO:0007411=TAS, GO:0007420=IEA, GO:0006915=IEA, GO:0016021=IEA} apoptotic process, axon guidance, brain development, positive regulation of apoptotic process, regulation of cell migration integral to membrane, plasma membrane netrin receptor activity Human UNC5CL UniProtKB UniProtKB {GO:0007165=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q8IV45 UNC5C-like protein protein 20130413 {GO:0007165=IEA, GO:0005737=IEA, GO:0016021=IEA} signal transduction cytoplasm, integral to membrane Human UniProtKB-SubCell:SL-0086 UNC79 Reactome UniProtKB {GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_160155, GO:0035264=GO_REF:0000019, GO:0048149=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_15518} Q9P2D8 Protein unc-79 homolog protein 20121204 {GO:0034220=TAS, GO:0005886=TAS, GO:0035264=IEA, GO:0048149=IEA, GO:0016021=IEA, GO:0055085=TAS} behavioral response to ethanol, ion transmembrane transport, multicellular organism growth, transmembrane transport integral to membrane, plasma membrane Human UNC80 Reactome UniProtKB {GO:0034220=Reactome:REACT_25300, GO:0005886=Reactome:REACT_160155, GO:0016021=GO_REF:0000037, GO:0055085=Reactome:REACT_15518} Q8N2C7 Protein unc-80 homolog protein 20121204 {GO:0034220=TAS, GO:0005886=TAS, GO:0016021=IEA, GO:0055085=TAS} ion transmembrane transport, transmembrane transport integral to membrane, plasma membrane Human UNC93B1 Reactome UniProtKB {GO:0034154=PMID:19006693, GO:0005783=PMID:21642595, GO:0032009=GO_REF:0000024, GO:0002224=Reactome:REACT_6966, GO:0006886=GO_REF:0000024, GO:0005764=GO_REF:0000024, GO:0051607=GO_REF:0000037, GO:0000139=Reactome:REACT_118791, GO:0045087=Reactome:REACT_6802, GO:0005789=Reactome:REACT_118802, GO:0016021=GO_REF:0000037, GO:0034138=PMID:18082565, GO:0034162=PMID:19006693, GO:0005768=GO_REF:0000024} Q9H1C4 Protein unc-93 homolog B1 protein 20111019 {GO:0034154=IMP, GO:0005783=IDA, GO:0032009=ISS, GO:0002224=TAS, GO:0006886=ISS, GO:0005764=ISS, GO:0051607=IEA, GO:0000139=TAS, GO:0045087=TAS, GO:0005789=TAS, GO:0016021=IEA, GO:0034138=IMP, GO:0034162=IMP, GO:0005768=ISS} defense response to virus, innate immune response, intracellular protein transport, toll-like receptor 3 signaling pathway, toll-like receptor 7 signaling pathway, toll-like receptor 9 signaling pathway, toll-like receptor signaling pathway Golgi membrane, early phagosome, endoplasmic reticulum, endoplasmic reticulum membrane, endosome, integral to membrane, lysosome Human UNG UniProtKB UniProtKB {GO:0005739=GO_REF:0000039, GO:0004844=PMID:9016624, GO:0006281=GO_REF:0000029, GO:0019048=GO_REF:0000037, GO:0006284=GO_REF:0000002, GO:0016447=GO_REF:0000019, GO:0005634=PMID:9016624, GO:0016446=GO_REF:0000019} P13051 Uracil-DNA glycosylase protein 20050308 {GO:0005739=IEA, GO:0004844=NAS, GO:0006281=NAS, GO:0019048=IEA, GO:0006284=IEA, GO:0016447=IEA, GO:0005634=NAS, GO:0016446=IEA} DNA repair, base-excision repair, somatic hypermutation of immunoglobulin genes, somatic recombination of immunoglobulin gene segments, virus-host interaction mitochondrion, nucleus uracil DNA N-glycosylase activity Human UNK InterPro UniProtKB {GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q9C0B0 RING finger protein unkempt homolog protein 20130413 {GO:0008270=IEA, GO:0003676=IEA} nucleic acid binding, zinc ion binding Human InterPro:IPR000571|InterPro:IPR001841 UNKL UniPathway UniProtKB {GO:0005737=GO_REF:0000039, GO:0016567=GO_REF:0000041, GO:0016874=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q9H9P5 Putative E3 ubiquitin-protein ligase UNKL protein 20130413 {GO:0005737=IEA, GO:0016567=IEA, GO:0016874=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA} protein ubiquitination cytoplasm, nucleus ligase activity, nucleic acid binding, zinc ion binding Human UniPathway:UPA00143 UPB1 Reactome UniProtKB {GO:0019483=GO_REF:0000041, GO:0006807=GO_REF:0000002, GO:0046135=Reactome:REACT_1023, GO:0016810=GO_REF:0000002, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0003837=Reactome:REACT_2183, GO:0006206=Reactome:REACT_957, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_2183} Q9UBR1 Beta-ureidopropionase protein 20130213 {GO:0019483=IEA, GO:0006807=IEA, GO:0046135=TAS, GO:0016810=IEA, GO:0055086=TAS, GO:0044281=TAS, GO:0003837=EXP, GO:0006206=TAS, GO:0046872=IEA, GO:0005829=TAS} beta-alanine biosynthetic process, nitrogen compound metabolic process, nucleobase-containing small molecule metabolic process, pyrimidine nucleobase metabolic process, pyrimidine nucleoside catabolic process, small molecule metabolic process cytosol beta-ureidopropionase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, metal ion binding Human UPF1 IntAct UniProtKB {GO:0005515=PMID:19417104, GO:0010467=Reactome:REACT_71, GO:0003723=PMID:10999600, GO:0009048=GO_REF:0000019, GO:0005634=PMID:18362360, GO:0006449=PMID:9620853, GO:0005829=Reactome:REACT_75917, GO:0004004=PMID:12554878, GO:0005737=PMID:9064659, GO:0006406=PMID:16488880, GO:0000184=Reactome:REACT_75886, GO:0044530=PMID:18362360, GO:0000932=GO_REF:0000039, GO:0000785=PMID:16488880, GO:0035145=PMID:16601204, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0004386=PMID:9064659, GO:0005524=GO_REF:0000037, GO:0003677=GO_REF:0000002, GO:0006260=PMID:16488880, GO:0007049=PMID:16488880, GO:0006281=PMID:16488880, GO:0003682=PMID:16488880, GO:0071044=PMID:16086026, GO:0008270=GO_REF:0000002} Q92900 Regulator of nonsense transcripts 1 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0003723=NAS, GO:0009048=IEA, GO:0005634=IDA, GO:0006449=IMP, GO:0005829=TAS, GO:0004004=IDA, GO:0005737=NAS, GO:0006406=TAS, GO:0000184=TAS, GO:0044530=IDA, GO:0000932=IEA, GO:0000785=IDA, GO:0035145=IDA, GO:0016070=TAS, GO:0016071=TAS, GO:0004386=NAS, GO:0005524=IEA, GO:0003677=IEA, GO:0006260=IMP, GO:0007049=IMP, GO:0006281=IDA, GO:0003682=IDA, GO:0071044=IMP, GO:0008270=IEA} DNA repair, DNA replication, RNA metabolic process, cell cycle, dosage compensation by inactivation of X chromosome, gene expression, histone mRNA catabolic process, mRNA export from nucleus, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, regulation of translational termination chromatin, cytoplasm, cytoplasmic mRNA processing body, cytosol, exon-exon junction complex, nucleus, supraspliceosomal complex ATP binding, ATP-dependent RNA helicase activity, DNA binding, RNA binding, chromatin binding, helicase activity, protein binding, zinc ion binding Human UniProtKB:Q9HAU5 UPF2 IntAct UniProtKB {GO:0005515=PMID:19417104, GO:0010467=Reactome:REACT_71, GO:0048471=GO_REF:0000039, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=GO_REF:0000037, GO:0031100=GO_REF:0000019, GO:0005634=PMID:14636577, GO:0003677=GO_REF:0000002, GO:0005829=Reactome:REACT_75910, GO:0001889=GO_REF:0000019, GO:0005737=PMID:14636577, GO:0006406=PMID:16488880, GO:0000184=Reactome:REACT_75886, GO:0035145=PMID:16601204} Q9HAU5 Regulator of nonsense transcripts 2 protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0048471=IEA, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=IEA, GO:0031100=IEA, GO:0005634=IDA, GO:0003677=IEA, GO:0005829=TAS, GO:0001889=IEA, GO:0005737=IDA, GO:0006406=TAS, GO:0000184=TAS, GO:0035145=IDA} RNA metabolic process, gene expression, liver development, mRNA export from nucleus, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, organ regeneration cytoplasm, cytosol, exon-exon junction complex, nucleus, perinuclear region of cytoplasm DNA binding, RNA binding, protein binding Human UniProtKB:Q92900 UPF3A GOC UniProtKB {GO:0005515=PMID:12417715, GO:0010467=Reactome:REACT_71, GO:0005886=GO_REF:0000052, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0045727=PMID:16601204, GO:0006913=PMID:11163187, GO:0005829=Reactome:REACT_75910, GO:0005737=GO_REF:0000052, GO:0000184=Reactome:REACT_75886, GO:0005487=PMID:11163187, GO:0000166=GO_REF:0000002, GO:0051028=GO_REF:0000037, GO:0035145=PMID:16601204} Q9H1J1 Regulator of nonsense transcripts 3A protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0005886=IDA, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0045727=IDA, GO:0006913=NAS, GO:0005829=TAS, GO:0005737=IDA, GO:0000184=TAS, GO:0005487=NAS, GO:0000166=IEA, GO:0051028=IEA, GO:0035145=IDA} RNA metabolic process, gene expression, mRNA metabolic process, mRNA transport, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, nucleocytoplasmic transport, positive regulation of translation cytoplasm, cytosol, exon-exon junction complex, nucleolus, nucleus, plasma membrane RNA binding, nucleocytoplasmic transporter activity, nucleotide binding, protein binding Human UPF3B HPA UniProtKB {GO:0005515=PMID:23084401, GO:0008380=Reactome:REACT_1735, GO:0010467=Reactome:REACT_71, GO:0006369=Reactome:REACT_894, GO:0016070=Reactome:REACT_21257, GO:0006366=Reactome:REACT_1366, GO:0016071=Reactome:REACT_20605, GO:0031124=Reactome:REACT_1849, GO:0005634=PMID:11163187, GO:0045727=PMID:16601204, GO:0003729=PMID:11546873, GO:0005829=Reactome:REACT_75910, GO:0005737=GO_REF:0000052, GO:0006406=Reactome:REACT_1597, GO:0005487=PMID:11163187, GO:0000184=Reactome:REACT_75886, GO:0000166=GO_REF:0000002, GO:0000398=Reactome:REACT_467, GO:0005654=Reactome:REACT_2104, GO:0035145=PMID:12718880} Q9BZI7 Regulator of nonsense transcripts 3B protein 20101115 {GO:0005515=IPI, GO:0008380=TAS, GO:0010467=TAS, GO:0006369=TAS, GO:0016070=TAS, GO:0006366=TAS, GO:0016071=TAS, GO:0031124=TAS, GO:0005634=NAS, GO:0045727=IDA, GO:0003729=IDA, GO:0005829=TAS, GO:0005737=IDA, GO:0006406=TAS, GO:0005487=NAS, GO:0000184=TAS, GO:0000166=IEA, GO:0000398=TAS, GO:0005654=TAS, GO:0035145=IDA} RNA metabolic process, RNA splicing, gene expression, mRNA 3'-end processing, mRNA export from nucleus, mRNA metabolic process, mRNA splicing, via spliceosome, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, positive regulation of translation, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter cytoplasm, cytosol, exon-exon junction complex, nucleoplasm, nucleus mRNA binding, nucleocytoplasmic transporter activity, nucleotide binding, protein binding Human UPK1A UniProtKB UniProtKB {GO:0016324=GO_REF:0000019, GO:0005886=GO_REF:0000024, GO:0005783=GO_REF:0000024, GO:0030855=PMID:10514386, GO:0016021=GO_REF:0000024, GO:0048029=GO_REF:0000024, GO:0051259=GO_REF:0000024, GO:0042803=GO_REF:0000024} O00322 Uroplakin-1a protein 20060313 {GO:0016324=IEA, GO:0005886=ISS, GO:0005783=ISS, GO:0030855=IDA, GO:0016021=ISS, GO:0048029=ISS, GO:0051259=ISS, GO:0042803=ISS} epithelial cell differentiation, protein oligomerization apical plasma membrane, endoplasmic reticulum, integral to membrane, plasma membrane monosaccharide binding, protein homodimerization activity Human UPK1B UniProtKB UniProtKB {GO:0016324=GO_REF:0000019, GO:0005198=PMID:9935153, GO:0030855=PMID:10514386, GO:0016021=PMID:9818021} O75841 Uroplakin-1b protein 20060313 {GO:0016324=IEA, GO:0005198=NAS, GO:0030855=IDA, GO:0016021=NAS} epithelial cell differentiation apical plasma membrane, integral to membrane structural molecule activity Human UPK2 PINC UniProtKB {GO:0016324=GO_REF:0000019, GO:0005887=PMID:8175808, GO:0030855=PMID:10514386, GO:0007275=PMID:9515818, GO:0030176=GO_REF:0000002, GO:0016044=GO_REF:0000002} O00526 Uroplakin-2 protein 20030904 {GO:0016324=IEA, GO:0005887=TAS, GO:0030855=IDA, GO:0007275=TAS, GO:0030176=IEA, GO:0016044=IEA} cellular membrane organization, epithelial cell differentiation, multicellular organismal development apical plasma membrane, integral to endoplasmic reticulum membrane, integral to plasma membrane Human UPK3A UniProtKB UniProtKB {GO:0000902=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0001822=GO_REF:0000019, GO:0030855=PMID:10514386, GO:0005789=GO_REF:0000039, GO:0060157=GO_REF:0000019, GO:0055075=GO_REF:0000019, GO:0055078=GO_REF:0000019, GO:0006833=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0015840=GO_REF:0000019} O75631 Uroplakin-3a protein 20060313 {GO:0000902=IEA, GO:0016324=IEA, GO:0001822=IEA, GO:0030855=IDA, GO:0005789=IEA, GO:0060157=IEA, GO:0055075=IEA, GO:0055078=IEA, GO:0006833=IEA, GO:0016021=IEA, GO:0015840=IEA} cell morphogenesis, epithelial cell differentiation, kidney development, potassium ion homeostasis, sodium ion homeostasis, urea transport, urinary bladder development, water transport apical plasma membrane, endoplasmic reticulum membrane, integral to membrane Human UPK3B UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0010629=PMID:18776082, GO:0016021=GO_REF:0000037} Q9BT76 Uroplakin-3b protein 20090720 {GO:0005886=IEA, GO:0010629=IMP, GO:0016021=IEA} negative regulation of gene expression integral to membrane, plasma membrane Human UPK3BL UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} B0FP48 Uroplakin-3b-like protein protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 UPP1 InterPro UniProtKB {GO:0044206=GO_REF:0000041, GO:0055086=Reactome:REACT_1698, GO:0006220=GO_REF:0000019, GO:0043097=Reactome:REACT_655, GO:0044281=Reactome:REACT_111217, GO:0009166=GO_REF:0000002, GO:0046108=GO_REF:0000019, GO:0005829=Reactome:REACT_2200, GO:0046135=Reactome:REACT_1023, GO:0005737=GO_REF:0000002, GO:0006139=PMID:7488099, GO:0009116=GO_REF:0000002, GO:0042149=GO_REF:0000019, GO:0006206=Reactome:REACT_957, GO:0004850=GO_REF:0000002} Q86Y75 UPP1 protein protein 20130413 {GO:0044206=IEA, GO:0055086=TAS, GO:0006220=IEA, GO:0043097=TAS, GO:0044281=TAS, GO:0009166=IEA, GO:0046108=IEA, GO:0005829=TAS, GO:0046135=TAS, GO:0005737=IEA, GO:0006139=TAS, GO:0009116=IEA, GO:0042149=IEA, GO:0006206=TAS, GO:0004850=IEA} UMP salvage, cellular response to glucose starvation, nucleobase-containing compound metabolic process, nucleobase-containing small molecule metabolic process, nucleoside metabolic process, nucleotide catabolic process, pyrimidine nucleobase metabolic process, pyrimidine nucleoside catabolic process, pyrimidine nucleoside salvage, pyrimidine nucleotide metabolic process, small molecule metabolic process, uridine metabolic process cytoplasm, cytosol uridine phosphorylase activity Human InterPro:IPR010059 UPP2 Reactome UniProtKB {GO:0046135=Reactome:REACT_1023, GO:0044206=GO_REF:0000041, GO:0045098=PMID:11278417, GO:0009116=PMID:12849978, GO:0055086=Reactome:REACT_1698, GO:0044281=Reactome:REACT_111217, GO:0043097=Reactome:REACT_655, GO:0006206=Reactome:REACT_957, GO:0046108=PMID:11278417, GO:0009166=GO_REF:0000002, GO:0004850=PMID:12849978, GO:0005829=Reactome:REACT_2200} O95045 Uridine phosphorylase 2 protein 20130301 {GO:0046135=TAS, GO:0044206=IEA, GO:0045098=IDA, GO:0009116=NAS, GO:0055086=TAS, GO:0044281=TAS, GO:0043097=TAS, GO:0006206=TAS, GO:0046108=NAS, GO:0009166=IEA, GO:0004850=IDA, GO:0005829=TAS} UMP salvage, nucleobase-containing small molecule metabolic process, nucleoside metabolic process, nucleotide catabolic process, pyrimidine nucleobase metabolic process, pyrimidine nucleoside catabolic process, pyrimidine nucleoside salvage, small molecule metabolic process, uridine metabolic process cytosol, type III intermediate filament uridine phosphorylase activity Human UPRT UniProtKB UniProtKB {GO:0032868=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0007565=GO_REF:0000019, GO:0007595=GO_REF:0000019, GO:0006222=GO_REF:0000019, GO:0005634=GO_REF:0000039} Q96BW1 Uracil phosphoribosyltransferase homolog protein 20130413 {GO:0032868=IEA, GO:0005737=IEA, GO:0007565=IEA, GO:0007595=IEA, GO:0006222=IEA, GO:0005634=IEA} UMP biosynthetic process, female pregnancy, lactation, response to insulin stimulus cytoplasm, nucleus Human UniProtKB-SubCell:SL-0086 UQCC UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0016023=GO_REF:0000039} Q9NVA1 Ubiquinol-cytochrome c reductase complex chaperone CBP3 homolog protein 20130413 {GO:0005739=IEA, GO:0016023=IEA} cytoplasmic membrane-bounded vesicle, mitochondrion Human UniProtKB-SubCell:SL-0088 UQCR10 Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0008121=PMID:8592474, GO:0006122=PMID:8592474, GO:0005743=Reactome:REACT_6300, GO:0005750=GO_REF:0000002, GO:0044281=Reactome:REACT_111217} Q9UDW1 Cytochrome b-c1 complex subunit 9 protein 20130213 {GO:0022904=TAS, GO:0008121=NAS, GO:0006122=NAS, GO:0005743=TAS, GO:0005750=IEA, GO:0044281=TAS} mitochondrial electron transport, ubiquinol to cytochrome c, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial respiratory chain complex III ubiquinol-cytochrome-c reductase activity Human UQCR11 Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0008121=GO_REF:0000002, GO:0070469=GO_REF:0000037, GO:0005743=Reactome:REACT_6300, GO:0009055=PMID:9161705, GO:0044281=Reactome:REACT_111217, GO:0006091=PMID:9161705, GO:0016021=GO_REF:0000037} O14957 Cytochrome b-c1 complex subunit 10 protein 20130213 {GO:0022904=TAS, GO:0008121=IEA, GO:0070469=IEA, GO:0005743=TAS, GO:0009055=TAS, GO:0044281=TAS, GO:0006091=TAS, GO:0016021=IEA} generation of precursor metabolites and energy, respiratory electron transport chain, small molecule metabolic process integral to membrane, mitochondrial inner membrane, respiratory chain electron carrier activity, ubiquinol-cytochrome-c reductase activity Human UQCRB Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0009060=PMID:3056408, GO:0005746=PMID:3056408, GO:0006122=GO_REF:0000002, GO:0005743=Reactome:REACT_6300, GO:0005750=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0006119=PMID:3056408, GO:0055114=PMID:3056408} P14927 Cytochrome b-c1 complex subunit 7 protein 20130213 {GO:0022904=TAS, GO:0009060=TAS, GO:0005746=TAS, GO:0006122=IEA, GO:0005743=TAS, GO:0005750=IEA, GO:0044281=TAS, GO:0006119=TAS, GO:0055114=TAS} aerobic respiration, mitochondrial electron transport, ubiquinol to cytochrome c, oxidation-reduction process, oxidative phosphorylation, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial respiratory chain, mitochondrial respiratory chain complex III Human UQCRC1 HPA UniProtKB {GO:0014823=GO_REF:0000019, GO:0005743=Reactome:REACT_6300, GO:0005750=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0043279=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0046872=GO_REF:0000002, GO:0006119=PMID:8407948, GO:0005739=GO_REF:0000052, GO:0009060=PMID:8407948, GO:0022904=Reactome:REACT_22393, GO:0005746=PMID:8407948, GO:0008121=PMID:8407948, GO:0006122=GO_REF:0000019, GO:0055114=PMID:8407948} P31930 Cytochrome b-c1 complex subunit 1, mitochondrial protein 20101115 {GO:0014823=IEA, GO:0005743=TAS, GO:0005750=IEA, GO:0044281=TAS, GO:0043279=IEA, GO:0032403=IEA, GO:0046872=IEA, GO:0006119=TAS, GO:0005739=IDA, GO:0009060=TAS, GO:0022904=TAS, GO:0005746=TAS, GO:0008121=TAS, GO:0006122=IEA, GO:0055114=TAS} aerobic respiration, mitochondrial electron transport, ubiquinol to cytochrome c, oxidation-reduction process, oxidative phosphorylation, respiratory electron transport chain, response to activity, response to alkaloid, small molecule metabolic process mitochondrial inner membrane, mitochondrial respiratory chain, mitochondrial respiratory chain complex III, mitochondrion metal ion binding, protein complex binding, ubiquinol-cytochrome-c reductase activity Human UQCRC2 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0005515=PMID:21078624, GO:0022904=Reactome:REACT_22393, GO:0009060=PMID:8288258, GO:0005743=Reactome:REACT_6300, GO:0006508=GO_REF:0000002, GO:0005750=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0004222=GO_REF:0000002, GO:0032403=GO_REF:0000019, GO:0046872=GO_REF:0000002, GO:0006119=PMID:8288258} P22695 Cytochrome b-c1 complex subunit 2, mitochondrial protein 20081203 {GO:0005739=IDA, GO:0005515=IPI, GO:0022904=TAS, GO:0009060=TAS, GO:0005743=TAS, GO:0006508=IEA, GO:0005750=IEA, GO:0044281=TAS, GO:0004222=IEA, GO:0032403=IEA, GO:0046872=IEA, GO:0006119=TAS} aerobic respiration, oxidative phosphorylation, proteolysis, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial respiratory chain complex III, mitochondrion metal ion binding, metalloendopeptidase activity, protein binding, protein complex binding Human UQCRFS1 HPA UniProtKB {GO:0051537=GO_REF:0000037, GO:0042493=GO_REF:0000019, GO:0005743=Reactome:REACT_6300, GO:0005750=GO_REF:0000029, GO:0044281=Reactome:REACT_111217, GO:0032403=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005739=GO_REF:0000052, GO:0022904=Reactome:REACT_22393, GO:0008121=GO_REF:0000029, GO:0016021=GO_REF:0000037, GO:0009725=GO_REF:0000019, GO:0046677=GO_REF:0000019, GO:0055114=GO_REF:0000029} P47985 Cytochrome b-c1 complex subunit Rieske, mitochondrial protein 20111111 {GO:0051537=IEA, GO:0042493=IEA, GO:0005743=TAS, GO:0005750=NAS, GO:0044281=TAS, GO:0032403=IEA, GO:0046872=IEA, GO:0005739=IDA, GO:0022904=TAS, GO:0008121=NAS, GO:0016021=IEA, GO:0009725=IEA, GO:0046677=IEA, GO:0055114=NAS} oxidation-reduction process, respiratory electron transport chain, response to antibiotic, response to drug, response to hormone stimulus, small molecule metabolic process integral to membrane, mitochondrial inner membrane, mitochondrial respiratory chain complex III, mitochondrion 2 iron, 2 sulfur cluster binding, metal ion binding, protein complex binding, ubiquinol-cytochrome-c reductase activity Human UQCRH Reactome UniProtKB {GO:0022904=Reactome:REACT_22393, GO:0009060=PMID:2826252, GO:0005746=PMID:2826252, GO:0008121=GO_REF:0000002, GO:0006122=GO_REF:0000002, GO:0005743=Reactome:REACT_6300, GO:0005750=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0051291=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0006119=PMID:2826252, GO:0055114=PMID:2826252} P07919 Cytochrome b-c1 complex subunit 6, mitochondrial protein 20050517 {GO:0022904=TAS, GO:0009060=TAS, GO:0005746=TAS, GO:0008121=IEA, GO:0006122=IEA, GO:0005743=TAS, GO:0005750=IEA, GO:0044281=TAS, GO:0051291=IEA, GO:0032403=IEA, GO:0006119=TAS, GO:0055114=TAS} aerobic respiration, mitochondrial electron transport, ubiquinol to cytochrome c, oxidation-reduction process, oxidative phosphorylation, protein heterooligomerization, respiratory electron transport chain, small molecule metabolic process mitochondrial inner membrane, mitochondrial respiratory chain, mitochondrial respiratory chain complex III protein complex binding, ubiquinol-cytochrome-c reductase activity Human UQCRQ Reactome UniProtKB {GO:0070469=GO_REF:0000037, GO:0005743=Reactome:REACT_6300, GO:0021548=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0021854=GO_REF:0000019, GO:0021860=GO_REF:0000019, GO:0021539=GO_REF:0000019, GO:0021794=GO_REF:0000019, GO:0022904=Reactome:REACT_22393, GO:0021766=GO_REF:0000019, GO:0008121=GO_REF:0000002, GO:0021680=GO_REF:0000019, GO:0030901=GO_REF:0000019} O14949 Cytochrome b-c1 complex subunit 8 protein 20130213 {GO:0070469=IEA, GO:0005743=TAS, GO:0021548=IEA, GO:0044281=TAS, GO:0021854=IEA, GO:0021860=IEA, GO:0021539=IEA, GO:0021794=IEA, GO:0022904=TAS, GO:0021766=IEA, GO:0008121=IEA, GO:0021680=IEA, GO:0030901=IEA} cerebellar Purkinje cell layer development, hippocampus development, hypothalamus development, midbrain development, pons development, pyramidal neuron development, respiratory electron transport chain, small molecule metabolic process, subthalamus development, thalamus development mitochondrial inner membrane, respiratory chain ubiquinol-cytochrome-c reductase activity Human URB1 HPA UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005730=GO_REF:0000052} O60287 Nucleolar pre-ribosomal-associated protein 1 protein 20090616 {GO:0003674=ND, GO:0008150=ND, GO:0005730=IDA} biological_process nucleolus molecular_function Human URB2 HPA UniProtKB {GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q14146 Unhealthy ribosome biogenesis protein 2 homolog protein 20081203 {GO:0005730=IDA, GO:0005634=IDA} nucleolus, nucleus Human URGCP UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0007049=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0005525=GO_REF:0000002} Q8TCY9 Up-regulator of cell proliferation protein 20130413 {GO:0005737=IEA, GO:0007049=IEA, GO:0005634=IEA, GO:0005525=IEA} cell cycle cytoplasm, nucleus GTP binding Human UniProtKB-SubCell:SL-0086 URI1 IntAct UniProtKB {GO:0005515=PMID:21397856, GO:0006357=PMID:9819440, GO:0001106=PMID:21730289, GO:0016272=GO_REF:0000002, GO:0004864=GO_REF:0000037, GO:0042981=PMID:17936702, GO:0005634=PMID:21730289, GO:0000122=PMID:21730289, GO:0009615=PMID:9819440, GO:0001558=PMID:21730289, GO:0030425=GO_REF:0000039, GO:0005739=GO_REF:0000039, GO:0005737=PMID:21730289, GO:0071363=PMID:17936702, GO:0006457=GO_REF:0000002, GO:0003682=PMID:21730289, GO:0071383=PMID:21730289, GO:0010923=PMID:17936702, GO:0005665=PMID:9819440, GO:0051082=GO_REF:0000002} O94763 Unconventional prefoldin RPB5 interactor 1 protein 20130415 {GO:0005515=IPI, GO:0006357=IMP, GO:0001106=IDA, GO:0016272=IEA, GO:0004864=IEA, GO:0042981=IMP, GO:0005634=IDA, GO:0000122=IDA, GO:0009615=IMP, GO:0001558=IDA, GO:0030425=IEA, GO:0005739=IEA, GO:0005737=IDA, GO:0071363=IDA, GO:0006457=IEA, GO:0003682=IDA, GO:0071383=IDA, GO:0010923=IMP, GO:0005665=IDA, GO:0051082=IEA} cellular response to growth factor stimulus, cellular response to steroid hormone stimulus, negative regulation of phosphatase activity, negative regulation of transcription from RNA polymerase II promoter, protein folding, regulation of apoptotic process, regulation of cell growth, regulation of transcription from RNA polymerase II promoter, response to virus DNA-directed RNA polymerase II, core complex, cytoplasm, dendrite, mitochondrion, nucleus, prefoldin complex RNA polymerase II transcription corepressor activity, chromatin binding, protein binding, protein phosphatase inhibitor activity, unfolded protein binding Human UniProtKB:P36873 URM1 UniProtKB UniProtKB {GO:0002098=PMID:19017811, GO:0005515=PMID:19017811, GO:0016783=PMID:19017811, GO:0034227=PMID:19017811, GO:0005829=PMID:19017811} Q9BTM9 Ubiquitin-related modifier 1 homolog protein 20090323 {GO:0002098=IMP, GO:0005515=IPI, GO:0016783=IDA, GO:0034227=IMP, GO:0005829=IC} tRNA thio-modification, tRNA wobble uridine modification cytosol protein binding, sulfurtransferase activity Human UROC1 BHF-UCL UniProtKB {GO:0034641=Reactome:REACT_13, GO:0016153=PMID:19304569, GO:0019557=GO_REF:0000041, GO:0019556=GO_REF:0000041, GO:0006548=PMID:19304569, GO:0044281=Reactome:REACT_111217, GO:0005829=PMID:19304569} Q96N76 Urocanate hydratase protein 20110706 {GO:0034641=TAS, GO:0016153=IDA, GO:0019557=IEA, GO:0019556=IEA, GO:0006548=IMP, GO:0044281=TAS, GO:0005829=IDA} cellular nitrogen compound metabolic process, histidine catabolic process, histidine catabolic process to glutamate and formamide, histidine catabolic process to glutamate and formate, small molecule metabolic process cytosol urocanate hydratase activity Human UROD InterPro UniProtKB {GO:0005737=GO_REF:0000052, GO:0006778=Reactome:REACT_9431, GO:0004853=GO_REF:0000002, GO:0006779=GO_REF:0000002, GO:0015630=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0044281=Reactome:REACT_111217, GO:0006782=GO_REF:0000041, GO:0005829=Reactome:REACT_9436, GO:0006783=Reactome:REACT_9465} Q5T446 Uroporphyrinogen decarboxylase protein 20130413 {GO:0005737=IDA, GO:0006778=TAS, GO:0004853=IEA, GO:0006779=IEA, GO:0015630=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0044281=TAS, GO:0006782=IEA, GO:0005829=TAS, GO:0006783=TAS} heme biosynthetic process, porphyrin-containing compound biosynthetic process, porphyrin-containing compound metabolic process, protoporphyrinogen IX biosynthetic process, small molecule metabolic process cytoplasm, cytosol, microtubule cytoskeleton, nucleolus, nucleus uroporphyrinogen decarboxylase activity Human InterPro:IPR000257|InterPro:IPR006361 UROS InterPro UniProtKB {GO:0048037=GO_REF:0000019, GO:0006780=PMID:18004775, GO:0044281=Reactome:REACT_111217, GO:0006782=GO_REF:0000041, GO:0033014=GO_REF:0000002, GO:0006783=Reactome:REACT_9465, GO:0005829=Reactome:REACT_9526, GO:0071418=GO_REF:0000019, GO:0005739=GO_REF:0000024, GO:0006778=Reactome:REACT_9431, GO:0004852=GO_REF:0000002, GO:0071243=GO_REF:0000019, GO:0046677=GO_REF:0000019} Q5T3L9 Uroporphyrinogen-III synthase protein 20130413 {GO:0048037=IEA, GO:0006780=IDA, GO:0044281=TAS, GO:0006782=IEA, GO:0033014=IEA, GO:0006783=TAS, GO:0005829=TAS, GO:0071418=IEA, GO:0005739=ISS, GO:0006778=TAS, GO:0004852=IEA, GO:0071243=IEA, GO:0046677=IEA} cellular response to amine stimulus, cellular response to arsenic-containing substance, heme biosynthetic process, porphyrin-containing compound metabolic process, protoporphyrinogen IX biosynthetic process, response to antibiotic, small molecule metabolic process, tetrapyrrole biosynthetic process, uroporphyrinogen III biosynthetic process cytosol, mitochondrion cofactor binding, uroporphyrinogen-III synthase activity Human InterPro:IPR003754 USE1 HGNC UniProtKB {GO:0006888=PMID:16354670, GO:0005515=PMID:15272311, GO:0030163=PMID:16354670, GO:0005783=PMID:15029241, GO:0060628=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0071786=GO_REF:0000019, GO:0007041=PMID:16354670, GO:0016021=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0032940=PMID:16354670, GO:0005764=PMID:16354670} Q9NZ43 Vesicle transport protein USE1 protein 20060522 {GO:0006888=ISS, GO:0005515=IPI, GO:0030163=ISS, GO:0005783=IDA, GO:0060628=IEA, GO:0005789=IEA, GO:0071786=IEA, GO:0007041=ISS, GO:0016021=IEA, GO:0015031=IEA, GO:0032940=ISS, GO:0005764=ISS} ER to Golgi vesicle-mediated transport, endoplasmic reticulum tubular network organization, lysosomal transport, protein catabolic process, protein transport, regulation of ER to Golgi vesicle-mediated transport, secretion by cell endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, lysosome protein binding Human UniProtKB:Q12981 USF1 BHF-UCL UniProtKB {GO:0005515=PMID:19303849, GO:0003700=GO_REF:0000019, GO:0042826=PMID:19303849, GO:0006366=PMID:2249772, GO:0003705=PMID:18234320, GO:0005634=PMID:18234320, GO:0045990=PMID:19303849, GO:0042803=PMID:8576131, GO:0003690=GO_REF:0000019, GO:0045944=PMID:18234320, GO:0046983=GO_REF:0000002, GO:0006006=GO_REF:0000019, GO:0000432=PMID:7852331, GO:0009411=GO_REF:0000024, GO:0005667=PMID:19303849, GO:0001666=PMID:12917334, GO:0032869=PMID:19303849, GO:0019086=PMID:2249772, GO:0046982=PMID:8576131, GO:0019901=PMID:19303849, GO:0006357=PMID:2249772, GO:0055088=GO_REF:0000024, GO:0051918=PMID:18234320, GO:0043425=PMID:8576131, GO:0042593=PMID:15054483, GO:0043565=PMID:8576131, GO:0000430=PMID:8576131, GO:0019899=PMID:19303849} P22415 Upstream stimulatory factor 1 protein 20080624 {GO:0005515=IPI, GO:0003700=IEA, GO:0042826=IPI, GO:0006366=IDA, GO:0003705=IMP, GO:0005634=IDA, GO:0045990=TAS, GO:0042803=IPI, GO:0003690=IEA, GO:0045944=IMP, GO:0046983=IEA, GO:0006006=IEA, GO:0000432=IMP, GO:0009411=ISS, GO:0005667=IDA, GO:0001666=IMP, GO:0032869=IDA, GO:0019086=IDA, GO:0046982=IPI, GO:0019901=IPI, GO:0006357=TAS, GO:0055088=ISS, GO:0051918=IC, GO:0043425=IPI, GO:0042593=TAS, GO:0043565=IDA, GO:0000430=IC, GO:0019899=IPI} carbon catabolite regulation of transcription, cellular response to insulin stimulus, glucose homeostasis, glucose metabolic process, late viral mRNA transcription, lipid homeostasis, negative regulation of fibrinolysis, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter by glucose, regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter by glucose, response to UV, response to hypoxia, transcription from RNA polymerase II promoter nucleus, transcription factor complex RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, bHLH transcription factor binding, double-stranded DNA binding, enzyme binding, histone deacetylase binding, protein binding, protein dimerization activity, protein heterodimerization activity, protein homodimerization activity, protein kinase binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human USF2 InterPro UniProtKB {GO:0005515=PMID:19505873, GO:0003700=GO_REF:0000019, GO:0046982=PMID:8576131, GO:0055088=GO_REF:0000024, GO:0043425=PMID:8576131, GO:0005634=PMID:8576131, GO:0000978=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0042803=PMID:8576131, GO:0043565=PMID:8576131, GO:0003690=GO_REF:0000019, GO:0007595=GO_REF:0000019, GO:0000430=PMID:8576131, GO:0046983=GO_REF:0000002, GO:0000432=PMID:7852331} Q6YI47 Upstream stimulatory factor 2 protein 20130413 {GO:0005515=IPI, GO:0003700=IEA, GO:0046982=IPI, GO:0055088=ISS, GO:0043425=IPI, GO:0005634=IDA, GO:0000978=IEA, GO:0006351=IEA, GO:0042803=IPI, GO:0043565=IDA, GO:0003690=IEA, GO:0007595=IEA, GO:0000430=IC, GO:0046983=IEA, GO:0000432=IMP} lactation, lipid homeostasis, positive regulation of transcription from RNA polymerase II promoter by glucose, regulation of transcription from RNA polymerase II promoter by glucose, transcription, DNA-dependent nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding, bHLH transcription factor binding, double-stranded DNA binding, protein binding, protein dimerization activity, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human InterPro:IPR011598 USH1C HGNC UniProtKB {GO:0005515=PMID:11311560, GO:0042472=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0042491=GO_REF:0000019, GO:0007605=PMID:11398101, GO:0030046=GO_REF:0000019, GO:0032420=PMID:16464467, GO:0045202=GO_REF:0000019, GO:0045177=PMID:10209257, GO:0045494=PMID:11398101, GO:0005829=GO_REF:0000039, GO:0001917=GO_REF:0000019, GO:0005737=PMID:10209257, GO:0000086=PMID:15219944, GO:0050957=PMID:10973247, GO:0005856=GO_REF:0000039, GO:0050953=PMID:11398101, GO:0001750=GO_REF:0000019} Q9Y6N9 Harmonin protein 20071018 {GO:0005515=IPI, GO:0042472=IEA, GO:0005886=IEA, GO:0042491=IEA, GO:0007605=IMP, GO:0030046=IEA, GO:0032420=TAS, GO:0045202=IEA, GO:0045177=IDA, GO:0045494=IMP, GO:0005829=IEA, GO:0001917=IEA, GO:0005737=IDA, GO:0000086=IMP, GO:0050957=IMP, GO:0005856=IEA, GO:0050953=IMP, GO:0001750=IEA} G2/M transition of mitotic cell cycle, auditory receptor cell differentiation, equilibrioception, inner ear morphogenesis, parallel actin filament bundle assembly, photoreceptor cell maintenance, sensory perception of light stimulus, sensory perception of sound apical part of cell, cytoplasm, cytoskeleton, cytosol, photoreceptor inner segment, photoreceptor outer segment, plasma membrane, stereocilium, synapse protein binding Human USH1G HGNC UniProtKB {GO:0005515=PMID:19028668, GO:0060113=GO_REF:0000019, GO:0042472=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0007605=PMID:12588794, GO:0050957=PMID:12588794, GO:0045494=PMID:11398101, GO:0015629=PMID:12588794, GO:0050953=PMID:11398101, GO:0042803=GO_REF:0000019, GO:0005829=GO_REF:0000039} Q495M9 Usher syndrome type-1G protein protein 20071018 {GO:0005515=IPI, GO:0060113=IEA, GO:0042472=IEA, GO:0005886=IEA, GO:0007605=IMP, GO:0050957=IMP, GO:0045494=IMP, GO:0015629=ISS, GO:0050953=IMP, GO:0042803=IEA, GO:0005829=IEA} equilibrioception, inner ear morphogenesis, inner ear receptor cell differentiation, photoreceptor cell maintenance, sensory perception of light stimulus, sensory perception of sound actin cytoskeleton, cytosol, plasma membrane protein binding, protein homodimerization activity Human USH2A BHF-UCL UniProtKB {GO:0005515=PMID:20440071, GO:0035315=GO_REF:0000024, GO:0060171=GO_REF:0000024, GO:0060113=GO_REF:0000024, GO:0002142=GO_REF:0000024, GO:0007605=PMID:10090909, GO:0005518=PMID:14676276, GO:0032421=GO_REF:0000024, GO:0048496=PMID:15671307, GO:0045494=PMID:10090909, GO:0005604=PMID:12433396, GO:0016324=GO_REF:0000024, GO:0005737=PMID:16434480, GO:0017022=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0050896=GO_REF:0000037, GO:0050953=PMID:10090909} O75445 Usherin protein 20120621 {GO:0005515=IPI, GO:0035315=ISS, GO:0060171=ISS, GO:0060113=ISS, GO:0002142=ISS, GO:0007605=IMP, GO:0005518=IDA, GO:0032421=ISS, GO:0048496=IMP, GO:0045494=IMP, GO:0005604=IDA, GO:0016324=ISS, GO:0005737=IDA, GO:0017022=ISS, GO:0016021=IEA, GO:0050896=IEA, GO:0050953=IMP} hair cell differentiation, inner ear receptor cell differentiation, maintenance of organ identity, photoreceptor cell maintenance, response to stimulus, sensory perception of light stimulus, sensory perception of sound apical plasma membrane, basement membrane, cytoplasm, integral to membrane, stereocilia ankle link complex, stereocilium bundle, stereocilium membrane collagen binding, myosin binding, protein binding Human UniProtKB:Q2QI47 USHBP1 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0030165=PMID:11311560} Q8N6Y0 Usher syndrome type-1C protein-binding protein 1 protein 20130415 {GO:0005515=IPI, GO:0030165=IPI} PDZ domain binding, protein binding Human UniProtKB:Q9UJW9 USMG5 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037, GO:0005753=GO_REF:0000024} Q96IX5 Up-regulated during skeletal muscle growth protein 5 protein 20120227 {GO:0016021=IEA, GO:0005753=ISS} integral to membrane, mitochondrial proton-transporting ATP synthase complex Human UniProtKB:Q3ZBI7 USO1 Reactome UniProtKB {GO:0048471=GO_REF:0000019, GO:0045056=GO_REF:0000019, GO:0000088=Reactome:REACT_765, GO:0000139=GO_REF:0000039, GO:0000087=Reactome:REACT_910, GO:0008565=GO_REF:0000002, GO:0048280=GO_REF:0000002, GO:0000278=Reactome:REACT_152, GO:0006886=GO_REF:0000002, GO:0005829=GO_REF:0000039} O60763 General vesicular transport factor p115 protein 20120605 {GO:0048471=IEA, GO:0045056=IEA, GO:0000088=TAS, GO:0000139=IEA, GO:0000087=TAS, GO:0008565=IEA, GO:0048280=IEA, GO:0000278=TAS, GO:0006886=IEA, GO:0005829=IEA} M phase of mitotic cell cycle, intracellular protein transport, mitotic cell cycle, mitotic prophase, transcytosis, vesicle fusion with Golgi apparatus Golgi membrane, cytosol, perinuclear region of cytoplasm protein transporter activity Human USP1 LIFEdb UniProtKB {GO:0004197=PMID:9827704, GO:0005515=PMID:18082604, GO:0006511=GO_REF:0000002, GO:0016579=PMID:18082604, GO:0006281=Reactome:REACT_216, GO:0004843=PMID:20129063, GO:0006282=PMID:18082604, GO:0035520=PMID:20129063, GO:0005654=Reactome:REACT_18350, GO:0005634=GO_REF:0000054, GO:0004221=PMID:18082604, GO:0009411=PMID:18082604} O94782 Ubiquitin carboxyl-terminal hydrolase 1 protein 20100607 {GO:0004197=TAS, GO:0005515=IPI, GO:0006511=IEA, GO:0016579=IDA, GO:0006281=TAS, GO:0004843=IMP, GO:0006282=IDA, GO:0035520=IMP, GO:0005654=TAS, GO:0005634=IDA, GO:0004221=IDA, GO:0009411=IDA} DNA repair, monoubiquitinated protein deubiquitination, protein deubiquitination, regulation of DNA repair, response to UV, ubiquitin-dependent protein catabolic process nucleoplasm, nucleus cysteine-type endopeptidase activity, protein binding, ubiquitin thiolesterase activity, ubiquitin-specific protease activity Human USP10 HPA UniProtKB {GO:0005515=PMID:21962518, GO:0006511=GO_REF:0000002, GO:0016579=PMID:20096447, GO:0004843=PMID:21962518, GO:0030330=PMID:20096447, GO:0006914=GO_REF:0000037, GO:0005634=PMID:20096447, GO:0044325=PMID:19398555, GO:0004197=PMID:21962518, GO:0002039=PMID:20096447, GO:0005737=GO_REF:0000052, GO:0006281=GO_REF:0000037, GO:0010506=PMID:21962518, GO:0045111=GO_REF:0000052, GO:0004221=PMID:21962518, GO:0005769=PMID:19398555} Q14694 Ubiquitin carboxyl-terminal hydrolase 10 protein 20101115 {GO:0005515=IPI, GO:0006511=IEA, GO:0016579=IDA, GO:0004843=IDA, GO:0030330=IMP, GO:0006914=IEA, GO:0005634=IDA, GO:0044325=IDA, GO:0004197=IMP, GO:0002039=IPI, GO:0005737=IDA, GO:0006281=IEA, GO:0010506=IDA, GO:0045111=IDA, GO:0004221=IDA, GO:0005769=IDA} DNA damage response, signal transduction by p53 class mediator, DNA repair, autophagy, protein deubiquitination, regulation of autophagy, ubiquitin-dependent protein catabolic process cytoplasm, early endosome, intermediate filament cytoskeleton, nucleus cysteine-type endopeptidase activity, ion channel binding, p53 binding, protein binding, ubiquitin thiolesterase activity, ubiquitin-specific protease activity Human USP11 InterPro UniProtKB {GO:0004197=PMID:9827704, GO:0005515=PMID:22190034, GO:0006511=GO_REF:0000002, GO:0016579=PMID:15314155, GO:0005737=GO_REF:0000052, GO:0004843=PMID:15314155, GO:0005634=PMID:15314155, GO:0008234=GO_REF:0000038, GO:0004221=GO_REF:0000002} Q5JXD3 Ubiquitin carboxyl-terminal hydrolase 11 protein 20130413 {GO:0004197=TAS, GO:0005515=IPI, GO:0006511=IEA, GO:0016579=IDA, GO:0005737=IDA, GO:0004843=IDA, GO:0005634=IDA, GO:0008234=IEA, GO:0004221=IEA} protein deubiquitination, ubiquitin-dependent protein catabolic process cytoplasm, nucleus cysteine-type endopeptidase activity, cysteine-type peptidase activity, protein binding, ubiquitin thiolesterase activity, ubiquitin-specific protease activity Human InterPro:IPR001394|InterPro:IPR018200 USP12 UniProtKB UniProtKB {GO:0005515=PMID:19075014, GO:0004197=PMID:19075014, GO:0006511=GO_REF:0000002, GO:0016579=PMID:19075014, GO:0004843=PMID:19075014, GO:0005575=GO_REF:0000015, GO:0004221=PMID:19075014, GO:0006464=GO_REF:0000029} O75317 Ubiquitin carboxyl-terminal hydrolase 12 protein 20090529 {GO:0005515=IPI, GO:0004197=IMP, GO:0006511=IEA, GO:0016579=IDA, GO:0004843=IDA, GO:0005575=ND, GO:0004221=IDA, GO:0006464=NAS} cellular protein modification process, protein deubiquitination, ubiquitin-dependent protein catabolic process cellular_component cysteine-type endopeptidase activity, protein binding, ubiquitin thiolesterase activity, ubiquitin-specific protease activity Human UniProtKB:Q8TAF3 USP13 UniProtKB UniProtKB {GO:0005515=PMID:21962518, GO:0006511=GO_REF:0000002, GO:0043130=PMID:22216260, GO:0006355=PMID:21811243, GO:0004843=PMID:21962518, GO:0008283=PMID:21811243, GO:0006914=GO_REF:0000037, GO:0050821=PMID:21659512, GO:0030318=PMID:21811243, GO:0004197=PMID:21811243, GO:0070536=PMID:22216260, GO:0010506=PMID:21962518, GO:0008270=GO_REF:0000002, GO:0004221=PMID:21962518, GO:0008242=GO_REF:0000002, GO:0031625=PMID:21659512} Q92995 Ubiquitin carboxyl-terminal hydrolase 13 protein 20120430 {GO:0005515=IPI, GO:0006511=IEA, GO:0043130=IDA, GO:0006355=IMP, GO:0004843=IDA, GO:0008283=IMP, GO:0006914=IEA, GO:0050821=IDA, GO:0030318=TAS, GO:0004197=IMP, GO:0070536=IDA, GO:0010506=IDA, GO:0008270=IEA, GO:0004221=IDA, GO:0008242=IEA, GO:0031625=IPI} autophagy, cell proliferation, melanocyte differentiation, protein K63-linked deubiquitination, protein stabilization, regulation of autophagy, regulation of transcription, DNA-dependent, ubiquitin-dependent protein catabolic process cysteine-type endopeptidase activity, omega peptidase activity, protein binding, ubiquitin binding, ubiquitin protein ligase binding, ubiquitin thiolesterase activity, ubiquitin-specific protease activity, zinc ion binding Human UniProtKB:Q14457 USP14 GOC UniProtKB {GO:0005515=PMID:19106094, GO:0006511=GO_REF:0000002, GO:0000502=GO_REF:0000037, GO:0004843=PMID:8579355, GO:0005886=GO_REF:0000039, GO:0009986=PMID:19106094, GO:0004866=PMID:18162577, GO:0008193=PMID:8579355, GO:0007268=GO_REF:0000019, GO:0045202=GO_REF:0000019, GO:0010951=PMID:18162577, GO:0004197=PMID:9827704, GO:0005737=GO_REF:0000052, GO:0050920=PMID:19106094, GO:0061136=PMID:18162577, GO:0070628=PMID:18162577, GO:0016023=PMID:19106094, GO:0004221=PMID:19106094, GO:0008234=GO_REF:0000038} P54578 Ubiquitin carboxyl-terminal hydrolase 14 protein 20130413 {GO:0005515=IPI, GO:0006511=IEA, GO:0000502=IEA, GO:0004843=TAS, GO:0005886=IEA, GO:0009986=IDA, GO:0004866=IMP, GO:0008193=TAS, GO:0007268=IEA, GO:0045202=IEA, GO:0010951=IMP, GO:0004197=TAS, GO:0005737=IDA, GO:0050920=IMP, GO:0061136=IMP, GO:0070628=IDA, GO:0016023=IDA, GO:0004221=IDA, GO:0008234=IEA} negative regulation of endopeptidase activity, regulation of chemotaxis, regulation of proteasomal protein catabolic process, synaptic transmission, ubiquitin-dependent protein catabolic process cell surface, cytoplasm, cytoplasmic membrane-bounded vesicle, plasma membrane, proteasome complex, synapse cysteine-type endopeptidase activity, cysteine-type peptidase activity, endopeptidase inhibitor activity, proteasome binding, protein binding, tRNA guanylyltransferase activity, ubiquitin thiolesterase activity, ubiquitin-specific protease activity Human USP15 Reactome UniProtKB {GO:0006511=GO_REF:0000002, GO:0016579=PMID:22344298, GO:0004843=PMID:22344298, GO:0005634=PMID:21947082, GO:0046332=PMID:22344298, GO:0030509=PMID:21947082, GO:0005160=PMID:22344298, GO:0004197=PMID:22344298, GO:0005737=PMID:21947082, GO:0035520=PMID:21947082, GO:0007179=Reactome:REACT_120850, GO:0008234=GO_REF:0000038, GO:0060389=PMID:22344298, GO:0004221=PMID:22344298, GO:0030512=Reactome:REACT_120727} Q9Y4E8 Ubiquitin carboxyl-terminal hydrolase 15 protein 20130301 {GO:0006511=IEA, GO:0016579=IDA, GO:0004843=IDA, GO:0005634=IDA, GO:0046332=IPI, GO:0030509=IDA, GO:0005160=IPI, GO:0004197=IMP, GO:0005737=IDA, GO:0035520=IDA, GO:0007179=TAS, GO:0008234=IEA, GO:0060389=IMP, GO:0004221=IDA, GO:0030512=TAS} BMP signaling pathway, monoubiquitinated protein deubiquitination, negative regulation of transforming growth factor beta receptor signaling pathway, pathway-restricted SMAD protein phosphorylation, protein deubiquitination, transforming growth factor beta receptor signaling pathway, ubiquitin-dependent protein catabolic process cytoplasm, nucleus SMAD binding, cysteine-type endopeptidase activity, cysteine-type peptidase activity, transforming growth factor beta receptor binding, ubiquitin thiolesterase activity, ubiquitin-specific protease activity Human USP16 PINC UniProtKB {GO:0006511=GO_REF:0000002, GO:0043130=PMID:17512543, GO:0016578=PMID:17914355, GO:0004843=PMID:17914355, GO:0003713=PMID:17914355, GO:0005634=PMID:17914355, GO:0006974=PMID:20550933, GO:0006351=GO_REF:0000037, GO:0004197=PMID:17914355, GO:0042393=PMID:17914355, GO:0007049=PMID:10077596, GO:0005737=PMID:10077596, GO:0007067=PMID:17914355, GO:0051289=PMID:17914355, GO:0070537=PMID:20550933, GO:0008270=PMID:17512543, GO:0004221=PMID:17914355, GO:0045893=PMID:17914355, GO:0045901=PMID:20550933, GO:0051301=GO_REF:0000037} Q9Y5T5 Ubiquitin carboxyl-terminal hydrolase 16 protein 20030904 {GO:0006511=IEA, GO:0043130=IDA, GO:0016578=IDA, GO:0004843=IDA, GO:0003713=IDA, GO:0005634=IDA, GO:0006974=IDA, GO:0006351=IEA, GO:0004197=IMP, GO:0042393=IDA, GO:0007049=TAS, GO:0005737=TAS, GO:0007067=IDA, GO:0051289=IPI, GO:0070537=IMP, GO:0008270=IDA, GO:0004221=IDA, GO:0045893=IMP, GO:0045901=IMP, GO:0051301=IEA} cell cycle, cell division, histone H2A K63-linked deubiquitination, histone deubiquitination, mitosis, positive regulation of transcription, DNA-dependent, positive regulation of translational elongation, protein homotetramerization, response to DNA damage stimulus, transcription, DNA-dependent, ubiquitin-dependent protein catabolic process cytoplasm, nucleus cysteine-type endopeptidase activity, histone binding, transcription coactivator activity, ubiquitin binding, ubiquitin thiolesterase activity, ubiquitin-specific protease activity, zinc ion binding Human USP17L2 UniProtKB UniProtKB {GO:0005515=PMID:21239494, GO:0006511=GO_REF:0000002, GO:0016579=PMID:20228808, GO:0007093=PMID:20228808, GO:0004843=PMID:20368735, GO:0071586=PMID:19188362, GO:1900246=PMID:20368735, GO:0005634=PMID:21239494, GO:1900245=PMID:20368735, GO:0070536=PMID:20368735, GO:1900027=PMID:21448158, GO:0042127=PMID:19188362, GO:0034261=PMID:19188362, GO:0071108=PMID:20368735, GO:0030334=PMID:21448158, GO:0006915=GO_REF:0000037, GO:0090315=PMID:19188362, GO:0042981=PMID:21239494, GO:0050691=PMID:20368735, GO:0032321=PMID:21448158, GO:0031064=PMID:21239494, GO:0005789=PMID:19188362, GO:0000075=PMID:20228808, GO:0004221=PMID:20228808, GO:0010955=PMID:19188362} Q6R6M4 Ubiquitin carboxyl-terminal hydrolase 17 protein 20121116 {GO:0005515=IPI, GO:0006511=IEA, GO:0016579=IDA, GO:0007093=IMP, GO:0004843=IMP, GO:0071586=IMP, GO:1900246=IMP, GO:0005634=IDA, GO:1900245=IMP, GO:0070536=IMP, GO:1900027=IMP, GO:0042127=IMP, GO:0034261=IDA, GO:0071108=IMP, GO:0030334=IMP, GO:0006915=IEA, GO:0090315=IMP, GO:0042981=IMP, GO:0050691=IMP, GO:0032321=IMP, GO:0031064=IMP, GO:0005789=IDA, GO:0000075=IMP, GO:0004221=IMP, GO:0010955=IMP} CAAX-box protein processing, apoptotic process, cell cycle checkpoint, mitotic cell cycle checkpoint, negative regulation of Ras GTPase activity, negative regulation of histone deacetylation, negative regulation of protein processing, negative regulation of protein targeting to membrane, positive regulation of MDA-5 signaling pathway, positive regulation of RIG-I signaling pathway, positive regulation of Rho GTPase activity, protein K48-linked deubiquitination, protein K63-linked deubiquitination, protein deubiquitination, regulation of apoptotic process, regulation of cell migration, regulation of cell proliferation, regulation of defense response to virus by host, regulation of ruffle assembly, ubiquitin-dependent protein catabolic process endoplasmic reticulum membrane, nucleus protein binding, ubiquitin thiolesterase activity, ubiquitin-specific protease activity Human USP17L7 UniProtKB UniProtKB {GO:0006511=GO_REF:0000002, GO:0005783=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0004221=GO_REF:0000002} P0C7H9 Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7 protein 20130413 {GO:0006511=IEA, GO:0005783=IEA, GO:0005634=IEA, GO:0004221=IEA} ubiquitin-dependent protein catabolic process endoplasmic reticulum, nucleus ubiquitin thiolesterase activity Human UniProtKB-SubCell:SL-0095 USP18 LIFEdb UniProtKB {GO:0006511=GO_REF:0000002, GO:0060337=Reactome:REACT_25162, GO:0004843=PMID:10777664, GO:0060338=Reactome:REACT_25216, GO:0019221=Reactome:REACT_25229, GO:0005634=GO_REF:0000054, GO:0004221=GO_REF:0000002, GO:0005829=Reactome:REACT_115684} Q9UMW8 Ubl carboxyl-terminal hydrolase 18 protein 20100607 {GO:0006511=IEA, GO:0060337=TAS, GO:0004843=TAS, GO:0060338=TAS, GO:0019221=TAS, GO:0005634=IDA, GO:0004221=IEA, GO:0005829=TAS} cytokine-mediated signaling pathway, regulation of type I interferon-mediated signaling pathway, type I interferon-mediated signaling pathway, ubiquitin-dependent protein catabolic process cytosol, nucleus ubiquitin thiolesterase activity, ubiquitin-specific protease activity Human USP19 UniProtKB UniProtKB {GO:0005515=PMID:21849505, GO:0006511=GO_REF:0000002, GO:0016579=GO_REF:0000024, GO:0034976=PMID:19465887, GO:0004843=PMID:19465887, GO:0014732=GO_REF:0000024, GO:0030433=PMID:19465887, GO:0048642=GO_REF:0000024, GO:0090068=GO_REF:0000024, GO:1900037=PMID:22128162, GO:0031647=GO_REF:0000024, GO:0005789=PMID:19465887, GO:0008270=GO_REF:0000002, GO:0008234=GO_REF:0000038, GO:0016021=GO_REF:0000037, GO:0004221=GO_REF:0000002} O94966 Ubiquitin carboxyl-terminal hydrolase 19 protein 20120126 {GO:0005515=IPI, GO:0006511=IEA, GO:0016579=ISS, GO:0034976=IEP, GO:0004843=IDA, GO:0014732=ISS, GO:0030433=IDA, GO:0048642=ISS, GO:0090068=ISS, GO:1900037=IMP, GO:0031647=ISS, GO:0005789=IDA, GO:0008270=IEA, GO:0008234=IEA, GO:0016021=IEA, GO:0004221=IEA} ER-associated protein catabolic process, negative regulation of skeletal muscle tissue development, positive regulation of cell cycle process, protein deubiquitination, regulation of cellular response to hypoxia, regulation of protein stability, response to endoplasmic reticulum stress, skeletal muscle atrophy, ubiquitin-dependent protein catabolic process endoplasmic reticulum membrane, integral to membrane cysteine-type peptidase activity, protein binding, ubiquitin thiolesterase activity, ubiquitin-specific protease activity, zinc ion binding Human UniProtKB:Q13489 USP2 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0006511=GO_REF:0000002, GO:0016579=PMID:19917254, GO:0005813=GO_REF:0000019, GO:0048471=GO_REF:0000039, GO:0030332=PMID:19917254, GO:0050821=PMID:17290220, GO:0005634=GO_REF:0000039, GO:0000122=PMID:17290220, GO:0048642=GO_REF:0000019, GO:0048643=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0042802=GO_REF:0000019, GO:0004197=PMID:9827704, GO:0045931=PMID:17290220, GO:0007049=GO_REF:0000037, GO:0007517=GO_REF:0000037, GO:0004221=PMID:19917254, GO:0008234=GO_REF:0000038, GO:0005938=GO_REF:0000019, GO:0031625=PMID:17290220} O75604 Ubiquitin carboxyl-terminal hydrolase 2 protein 20130415 {GO:0005515=IPI, GO:0006511=IEA, GO:0016579=IDA, GO:0005813=IEA, GO:0048471=IEA, GO:0030332=IPI, GO:0050821=IDA, GO:0005634=IEA, GO:0000122=IMP, GO:0048642=IEA, GO:0048643=IEA, GO:0046872=IEA, GO:0042802=IEA, GO:0004197=TAS, GO:0045931=IMP, GO:0007049=IEA, GO:0007517=IEA, GO:0004221=IMP, GO:0008234=IEA, GO:0005938=IEA, GO:0031625=IPI} cell cycle, muscle organ development, negative regulation of skeletal muscle tissue development, negative regulation of transcription from RNA polymerase II promoter, positive regulation of mitotic cell cycle, positive regulation of skeletal muscle tissue development, protein deubiquitination, protein stabilization, ubiquitin-dependent protein catabolic process cell cortex, centrosome, nucleus, perinuclear region of cytoplasm cyclin binding, cysteine-type endopeptidase activity, cysteine-type peptidase activity, identical protein binding, metal ion binding, protein binding, ubiquitin protein ligase binding, ubiquitin thiolesterase activity Human UniProtKB:P19012 USP20 UniProtKB UniProtKB {GO:0071108=PMID:19424180, GO:0004197=PMID:19424180, GO:0006511=GO_REF:0000002, GO:0016579=PMID:19424180, GO:0048471=GO_REF:0000039, GO:0001664=PMID:19424180, GO:0008277=PMID:19424180, GO:0070536=PMID:19424180, GO:0008270=GO_REF:0000002, GO:0004221=PMID:19424180, GO:0005575=GO_REF:0000015, GO:0006897=GO_REF:0000037} Q9Y2K6 Ubiquitin carboxyl-terminal hydrolase 20 protein 20091115 {GO:0071108=IDA, GO:0004197=IMP, GO:0006511=IEA, GO:0016579=IDA, GO:0048471=IEA, GO:0001664=IPI, GO:0008277=IMP, GO:0070536=IDA, GO:0008270=IEA, GO:0004221=IDA, GO:0005575=ND, GO:0006897=IEA} endocytosis, protein K48-linked deubiquitination, protein K63-linked deubiquitination, protein deubiquitination, regulation of G-protein coupled receptor protein signaling pathway, ubiquitin-dependent protein catabolic process cellular_component, perinuclear region of cytoplasm G-protein coupled receptor binding, cysteine-type endopeptidase activity, ubiquitin thiolesterase activity, zinc ion binding Human USP21 UniProtKB UniProtKB {GO:0006511=GO_REF:0000002, GO:0016578=GO_REF:0000024, GO:0004843=PMID:10799498, GO:0003713=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0006351=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0019784=PMID:10799498, GO:0005737=GO_REF:0000039, GO:0004221=PMID:10799498, GO:0008234=PMID:10799498, GO:0045893=GO_REF:0000024, GO:0006464=GO_REF:0000029} Q9UK80 Ubiquitin carboxyl-terminal hydrolase 21 protein 20090326 {GO:0006511=IEA, GO:0016578=ISS, GO:0004843=IDA, GO:0003713=ISS, GO:0005634=IEA, GO:0005575=ND, GO:0006351=IEA, GO:0046872=IEA, GO:0019784=IDA, GO:0005737=IEA, GO:0004221=IDA, GO:0008234=IMP, GO:0045893=ISS, GO:0006464=NAS} cellular protein modification process, histone deubiquitination, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent, ubiquitin-dependent protein catabolic process cellular_component, cytoplasm, nucleus NEDD8-specific protease activity, cysteine-type peptidase activity, metal ion binding, transcription coactivator activity, ubiquitin thiolesterase activity, ubiquitin-specific protease activity Human USP22 GOC UniProtKB {GO:0005515=PMID:18206972, GO:0006511=GO_REF:0000002, GO:0016578=PMID:18206972, GO:0016579=PMID:16378762, GO:0004843=PMID:16378762, GO:0016574=PMID:18469533, GO:0003713=PMID:18206972, GO:0009790=PMID:16378762, GO:0006351=GO_REF:0000037, GO:0070461=PMID:18838386, GO:0007049=GO_REF:0000037, GO:0045931=PMID:18206973, GO:0030374=PMID:18206972, GO:0043967=PMID:18206973, GO:0000124=PMID:18206973, GO:0008270=GO_REF:0000002, GO:0010485=PMID:18206973, GO:0004221=GO_REF:0000002, GO:0045893=PMID:18206973} Q9UPT9 Ubiquitin carboxyl-terminal hydrolase 22 protein 20130413 {GO:0005515=IPI, GO:0006511=IEA, GO:0016578=IDA, GO:0016579=IDA, GO:0004843=IDA, GO:0016574=IDA, GO:0003713=IDA, GO:0009790=NAS, GO:0006351=IEA, GO:0070461=IDA, GO:0007049=IEA, GO:0045931=IMP, GO:0030374=IMP, GO:0043967=IDA, GO:0000124=IDA, GO:0008270=IEA, GO:0010485=IDA, GO:0004221=IEA, GO:0045893=IMP} cell cycle, embryo development, histone H4 acetylation, histone deubiquitination, histone ubiquitination, positive regulation of mitotic cell cycle, positive regulation of transcription, DNA-dependent, protein deubiquitination, transcription, DNA-dependent, ubiquitin-dependent protein catabolic process SAGA complex, SAGA-type complex H4 histone acetyltransferase activity, ligand-dependent nuclear receptor transcription coactivator activity, protein binding, transcription coactivator activity, ubiquitin thiolesterase activity, ubiquitin-specific protease activity, zinc ion binding Human USP24 UniProtKB UniProtKB {GO:0006511=GO_REF:0000002, GO:0008234=GO_REF:0000037, GO:0004221=GO_REF:0000002} Q9UPU5 Ubiquitin carboxyl-terminal hydrolase 24 protein 20130413 {GO:0006511=IEA, GO:0008234=IEA, GO:0004221=IEA} ubiquitin-dependent protein catabolic process cysteine-type peptidase activity, ubiquitin thiolesterase activity Human UniProtKB-KW:KW-0788 USP25 PINC UniProtKB {GO:0071108=PMID:18538659, GO:0005515=PMID:18538659, GO:0006511=GO_REF:0000002, GO:0032183=PMID:18538659, GO:0005737=GO_REF:0000039, GO:0004843=PMID:18538659, GO:0070536=PMID:18538659, GO:0006508=PMID:10644437, GO:0008233=PMID:10644437, GO:0005634=GO_REF:0000039, GO:0004221=GO_REF:0000002, GO:0006464=PMID:10644437} Q9UHP3 Ubiquitin carboxyl-terminal hydrolase 25 protein 20030904 {GO:0071108=IMP, GO:0005515=IPI, GO:0006511=IEA, GO:0032183=IDA, GO:0005737=IEA, GO:0004843=IMP, GO:0070536=IMP, GO:0006508=TAS, GO:0008233=TAS, GO:0005634=IEA, GO:0004221=IEA, GO:0006464=TAS} cellular protein modification process, protein K48-linked deubiquitination, protein K63-linked deubiquitination, proteolysis, ubiquitin-dependent protein catabolic process cytoplasm, nucleus SUMO binding, peptidase activity, protein binding, ubiquitin thiolesterase activity, ubiquitin-specific protease activity Human USP26 UniProtKB UniProtKB {GO:0005515=PMID:20501646, GO:0006511=GO_REF:0000002, GO:0016579=PMID:20501646, GO:0005634=PMID:20501646, GO:0008234=GO_REF:0000037, GO:0004221=GO_REF:0000002} Q9BXU7 Ubiquitin carboxyl-terminal hydrolase 26 protein 20100601 {GO:0005515=IPI, GO:0006511=IEA, GO:0016579=IDA, GO:0005634=IDA, GO:0008234=IEA, GO:0004221=IEA} protein deubiquitination, ubiquitin-dependent protein catabolic process nucleus cysteine-type peptidase activity, protein binding, ubiquitin thiolesterase activity Human UniProtKB:P10275 USP27X UniProtKB UniProtKB {GO:0006511=GO_REF:0000002, GO:0008234=GO_REF:0000037, GO:0004221=GO_REF:0000002} A6NNY8 Ubiquitin carboxyl-terminal hydrolase 27 protein 20130413 {GO:0006511=IEA, GO:0008234=IEA, GO:0004221=IEA} ubiquitin-dependent protein catabolic process cysteine-type peptidase activity, ubiquitin thiolesterase activity Human UniProtKB-KW:KW-0788 USP28 HPA UniProtKB {GO:0005515=PMID:17873522, GO:0006511=GO_REF:0000002, GO:0016579=PMID:17558397, GO:0004843=PMID:17558397, GO:0008283=PMID:17558397, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006974=PMID:17873522, GO:0043234=PMID:17873522, GO:0042771=PMID:16901786, GO:0034644=PMID:17873522, GO:0006281=GO_REF:0000037, GO:0010212=PMID:16901786, GO:0005654=PMID:17558397, GO:0000077=PMID:18662541, GO:0004221=PMID:17558397, GO:0008234=GO_REF:0000038} Q96RU2 Ubiquitin carboxyl-terminal hydrolase 28 protein 20080205 {GO:0005515=IPI, GO:0006511=IEA, GO:0016579=IDA, GO:0004843=IDA, GO:0008283=IMP, GO:0005730=IDA, GO:0005634=IDA, GO:0006974=IDA, GO:0043234=IDA, GO:0042771=IDA, GO:0034644=IDA, GO:0006281=IEA, GO:0010212=IDA, GO:0005654=IDA, GO:0000077=IMP, GO:0004221=IMP, GO:0008234=IEA} DNA damage checkpoint, DNA repair, cell proliferation, cellular response to UV, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, protein deubiquitination, response to DNA damage stimulus, response to ionizing radiation, ubiquitin-dependent protein catabolic process nucleolus, nucleoplasm, nucleus, protein complex cysteine-type peptidase activity, protein binding, ubiquitin thiolesterase activity, ubiquitin-specific protease activity NOT Human USP29 UniProtKB UniProtKB {GO:0006511=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0004221=PMID:10958632, GO:0008234=GO_REF:0000037, GO:0006464=GO_REF:0000029} Q9HBJ7 Ubiquitin carboxyl-terminal hydrolase 29 protein 20061026 {GO:0006511=IEA, GO:0005575=ND, GO:0004221=TAS, GO:0008234=IEA, GO:0006464=NAS} cellular protein modification process, ubiquitin-dependent protein catabolic process cellular_component cysteine-type peptidase activity, ubiquitin thiolesterase activity Human USP3 PINC UniProtKB {GO:0016578=PMID:17980597, GO:0042393=PMID:17980597, GO:0006511=GO_REF:0000002, GO:0000790=PMID:17980597, GO:0004843=PMID:10480896, GO:0006281=PMID:17980597, GO:0031647=PMID:17980597, GO:0016787=GO_REF:0000038, GO:0008270=GO_REF:0000002, GO:0008234=GO_REF:0000038, GO:0004221=PMID:17980597, GO:0000278=PMID:17980597} Q9Y6I4 Ubiquitin carboxyl-terminal hydrolase 3 protein 20030904 {GO:0016578=IDA, GO:0042393=IPI, GO:0006511=IEA, GO:0000790=IDA, GO:0004843=TAS, GO:0006281=IMP, GO:0031647=IDA, GO:0016787=IEA, GO:0008270=IEA, GO:0008234=IEA, GO:0004221=IMP, GO:0000278=IMP} DNA repair, histone deubiquitination, mitotic cell cycle, regulation of protein stability, ubiquitin-dependent protein catabolic process nuclear chromatin cysteine-type peptidase activity, histone binding, hydrolase activity, ubiquitin thiolesterase activity, ubiquitin-specific protease activity, zinc ion binding Human USP30 UniProtKB UniProtKB {GO:0006511=GO_REF:0000002, GO:0005741=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0008234=GO_REF:0000037, GO:0004221=GO_REF:0000002} Q70CQ3 Ubiquitin carboxyl-terminal hydrolase 30 protein 20130413 {GO:0006511=IEA, GO:0005741=IEA, GO:0016021=IEA, GO:0008234=IEA, GO:0004221=IEA} ubiquitin-dependent protein catabolic process integral to membrane, mitochondrial outer membrane cysteine-type peptidase activity, ubiquitin thiolesterase activity Human UniProtKB-SubCell:SL-0172 USP31 UniProtKB UniProtKB {GO:0006511=GO_REF:0000002, GO:0008234=GO_REF:0000037, GO:0004221=GO_REF:0000002} Q70CQ4 Ubiquitin carboxyl-terminal hydrolase 31 protein 20130413 {GO:0006511=IEA, GO:0008234=IEA, GO:0004221=IEA} ubiquitin-dependent protein catabolic process cysteine-type peptidase activity, ubiquitin thiolesterase activity Human UniProtKB-KW:KW-0788 USP32 UniProtKB UniProtKB {GO:0006511=GO_REF:0000002, GO:0016579=PMID:20549504, GO:0005794=PMID:20549504, GO:0016020=GO_REF:0000039, GO:0005509=GO_REF:0000002, GO:0008234=GO_REF:0000037, GO:0004221=PMID:20549504} Q8NFA0 Ubiquitin carboxyl-terminal hydrolase 32 protein 20100625 {GO:0006511=IEA, GO:0016579=TAS, GO:0005794=IDA, GO:0016020=IEA, GO:0005509=IEA, GO:0008234=IEA, GO:0004221=IDA} protein deubiquitination, ubiquitin-dependent protein catabolic process Golgi apparatus, membrane calcium ion binding, cysteine-type peptidase activity, ubiquitin thiolesterase activity Human USP33 UniProtKB UniProtKB {GO:0071108=PMID:19363159, GO:0005515=PMID:19363159, GO:0043130=PMID:17766394, GO:0006511=PMID:11739384, GO:0048471=GO_REF:0000039, GO:0016579=PMID:19363159, GO:0001664=PMID:19424180, GO:0004843=PMID:11739384, GO:0030891=PMID:11739384, GO:0044297=GO_REF:0000019, GO:0006897=GO_REF:0000037, GO:0004197=PMID:19424180, GO:0005737=PMID:11739384, GO:0008277=PMID:19363159, GO:0070536=PMID:19363159, GO:0016477=GO_REF:0000024, GO:0007411=GO_REF:0000024, GO:0008270=PMID:17766394, GO:0004221=PMID:19424180} Q8TEY7 Ubiquitin carboxyl-terminal hydrolase 33 protein 20091115 {GO:0071108=IDA, GO:0005515=IPI, GO:0043130=IDA, GO:0006511=TAS, GO:0048471=IEA, GO:0016579=IDA, GO:0001664=IPI, GO:0004843=TAS, GO:0030891=TAS, GO:0044297=IEA, GO:0006897=IEA, GO:0004197=IMP, GO:0005737=TAS, GO:0008277=IMP, GO:0070536=IDA, GO:0016477=ISS, GO:0007411=ISS, GO:0008270=IDA, GO:0004221=IDA} axon guidance, cell migration, endocytosis, protein K48-linked deubiquitination, protein K63-linked deubiquitination, protein deubiquitination, regulation of G-protein coupled receptor protein signaling pathway, ubiquitin-dependent protein catabolic process VCB complex, cell body, cytoplasm, perinuclear region of cytoplasm G-protein coupled receptor binding, cysteine-type endopeptidase activity, protein binding, ubiquitin binding, ubiquitin thiolesterase activity, ubiquitin-specific protease activity, zinc ion binding Human UniProtKB:Q8R5K2 USP34 UniProtKB UniProtKB {GO:0004197=PMID:21383061, GO:0071108=PMID:21383061, GO:0005515=PMID:21383061, GO:0006511=GO_REF:0000002, GO:0004843=PMID:21383061, GO:0090263=PMID:21383061, GO:0004221=PMID:21383061, GO:0016055=GO_REF:0000037} Q70CQ2 Ubiquitin carboxyl-terminal hydrolase 34 protein 20110420 {GO:0004197=IMP, GO:0071108=IDA, GO:0005515=IPI, GO:0006511=IEA, GO:0004843=IDA, GO:0090263=IDA, GO:0004221=IDA, GO:0016055=IEA} Wnt receptor signaling pathway, positive regulation of canonical Wnt receptor signaling pathway, protein K48-linked deubiquitination, ubiquitin-dependent protein catabolic process cysteine-type endopeptidase activity, protein binding, ubiquitin thiolesterase activity, ubiquitin-specific protease activity Human UniProtKB:Q9Y2T1 USP35 UniProtKB UniProtKB {GO:0006511=GO_REF:0000002, GO:0008234=GO_REF:0000037, GO:0004221=GO_REF:0000002} Q9P2H5 Ubiquitin carboxyl-terminal hydrolase 35 protein 20130413 {GO:0006511=IEA, GO:0008234=IEA, GO:0004221=IEA} ubiquitin-dependent protein catabolic process cysteine-type peptidase activity, ubiquitin thiolesterase activity Human UniProtKB-KW:KW-0788 USP36 HPA UniProtKB {GO:0006511=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0008234=GO_REF:0000037, GO:0004221=GO_REF:0000002} Q9P275 Ubiquitin carboxyl-terminal hydrolase 36 protein 20081203 {GO:0006511=IEA, GO:0005730=IDA, GO:0008234=IEA, GO:0004221=IEA} ubiquitin-dependent protein catabolic process nucleolus cysteine-type peptidase activity, ubiquitin thiolesterase activity Human USP37 LIFEdb UniProtKB {GO:0005515=PMID:21596315, GO:0004197=PMID:21596315, GO:0071108=PMID:21596315, GO:0006511=GO_REF:0000002, GO:0000082=PMID:21596315, GO:0007067=GO_REF:0000037, GO:0004843=PMID:21596315, GO:0019901=PMID:21596315, GO:0005634=GO_REF:0000054, GO:0004221=GO_REF:0000002, GO:0035871=PMID:21596315, GO:0051301=GO_REF:0000037} Q86T82 Ubiquitin carboxyl-terminal hydrolase 37 protein 20100607 {GO:0005515=IPI, GO:0004197=IDA, GO:0071108=IDA, GO:0006511=IEA, GO:0000082=IDA, GO:0007067=IEA, GO:0004843=IDA, GO:0019901=IPI, GO:0005634=IDA, GO:0004221=IEA, GO:0035871=IDA, GO:0051301=IEA} G1/S transition of mitotic cell cycle, cell division, mitosis, protein K11-linked deubiquitination, protein K48-linked deubiquitination, ubiquitin-dependent protein catabolic process nucleus cysteine-type endopeptidase activity, protein binding, protein kinase binding, ubiquitin thiolesterase activity, ubiquitin-specific protease activity Human USP38 UniProtKB UniProtKB {GO:0006511=GO_REF:0000002, GO:0008234=GO_REF:0000037, GO:0004221=GO_REF:0000002} Q8NB14 Ubiquitin carboxyl-terminal hydrolase 38 protein 20130413 {GO:0006511=IEA, GO:0008234=IEA, GO:0004221=IEA} ubiquitin-dependent protein catabolic process cysteine-type peptidase activity, ubiquitin thiolesterase activity Human UniProtKB-KW:KW-0788 USP39 PINC UniProtKB {GO:0006397=PMID:10022888, GO:0008380=PMID:10022888, GO:0000245=PMID:10022888, GO:0006511=GO_REF:0000002, GO:0007049=GO_REF:0000037, GO:0005681=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0004221=GO_REF:0000002, GO:0051301=GO_REF:0000037} Q53GS9 U4/U6.U5 tri-snRNP-associated protein 2 protein 20061107 {GO:0006397=TAS, GO:0008380=TAS, GO:0000245=TAS, GO:0006511=IEA, GO:0007049=IEA, GO:0005681=IEA, GO:0008270=IEA, GO:0004221=IEA, GO:0051301=IEA} RNA splicing, cell cycle, cell division, mRNA processing, spliceosomal complex assembly, ubiquitin-dependent protein catabolic process spliceosomal complex ubiquitin thiolesterase activity, zinc ion binding Human USP4 IntAct UniProtKB {GO:0005515=PMID:16339847, GO:0006511=GO_REF:0000002, GO:0016579=PMID:16316627, GO:0004843=PMID:16316627, GO:0005634=PMID:16339847, GO:0005764=PMID:9827704, GO:0046872=GO_REF:0000037, GO:0031685=PMID:16339847, GO:0005737=PMID:16316627, GO:0031647=PMID:16472766, GO:0034394=PMID:16339847, GO:0008234=GO_REF:0000038, GO:0031397=PMID:16472766, GO:0004221=PMID:16316627} Q13107 Ubiquitin carboxyl-terminal hydrolase 4 protein 20130415 {GO:0005515=IPI, GO:0006511=IEA, GO:0016579=IDA, GO:0004843=IDA, GO:0005634=IDA, GO:0005764=TAS, GO:0046872=IEA, GO:0031685=IPI, GO:0005737=IDA, GO:0031647=IDA, GO:0034394=IDA, GO:0008234=IEA, GO:0031397=IMP, GO:0004221=IMP} negative regulation of protein ubiquitination, protein deubiquitination, protein localization to cell surface, regulation of protein stability, ubiquitin-dependent protein catabolic process cytoplasm, lysosome, nucleus adenosine receptor binding, cysteine-type peptidase activity, metal ion binding, protein binding, ubiquitin thiolesterase activity, ubiquitin-specific protease activity Human UniProtKB:P29274 USP40 UniProtKB UniProtKB {GO:0006511=GO_REF:0000002, GO:0008234=GO_REF:0000037, GO:0004221=GO_REF:0000002} Q9NVE5 Ubiquitin carboxyl-terminal hydrolase 40 protein 20130413 {GO:0006511=IEA, GO:0008234=IEA, GO:0004221=IEA} ubiquitin-dependent protein catabolic process cysteine-type peptidase activity, ubiquitin thiolesterase activity Human UniProtKB-KW:KW-0788 USP41 UniProtKB UniProtKB {GO:0006511=GO_REF:0000002, GO:0008234=GO_REF:0000037, GO:0004221=GO_REF:0000002} Q3LFD5 Putative ubiquitin carboxyl-terminal hydrolase 41 protein 20130413 {GO:0006511=IEA, GO:0008234=IEA, GO:0004221=IEA} ubiquitin-dependent protein catabolic process cysteine-type peptidase activity, ubiquitin thiolesterase activity Human UniProtKB-KW:KW-0788 USP42 UniProtKB UniProtKB {GO:0006511=GO_REF:0000002, GO:0016579=GO_REF:0000024, GO:0008234=GO_REF:0000037, GO:0007283=GO_REF:0000037, GO:0004221=GO_REF:0000002, GO:0030154=GO_REF:0000037} Q9H9J4 Ubiquitin carboxyl-terminal hydrolase 42 protein 20101208 {GO:0006511=IEA, GO:0016579=ISS, GO:0008234=IEA, GO:0007283=IEA, GO:0004221=IEA, GO:0030154=IEA} cell differentiation, protein deubiquitination, spermatogenesis, ubiquitin-dependent protein catabolic process cysteine-type peptidase activity, ubiquitin thiolesterase activity Human UniProtKB:B2RQC2 USP43 UniProtKB UniProtKB {GO:0006511=GO_REF:0000002, GO:0008234=GO_REF:0000037, GO:0004221=GO_REF:0000002} Q70EL4 Ubiquitin carboxyl-terminal hydrolase 43 protein 20130413 {GO:0006511=IEA, GO:0008234=IEA, GO:0004221=IEA} ubiquitin-dependent protein catabolic process cysteine-type peptidase activity, ubiquitin thiolesterase activity Human UniProtKB-KW:KW-0788 USP44 LIFEdb UniProtKB {GO:0005515=PMID:17443180, GO:0090231=PMID:17443180, GO:0006511=GO_REF:0000002, GO:0016579=PMID:20402667, GO:0004843=PMID:20402667, GO:0051322=PMID:17443180, GO:0090266=GO_REF:0000024, GO:0060564=PMID:17443180, GO:0005634=GO_REF:0000054, GO:0007067=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0043161=GO_REF:0000024, GO:0004221=PMID:20402667, GO:0008234=GO_REF:0000038, GO:0051301=GO_REF:0000037} Q9H0E7 Ubiquitin carboxyl-terminal hydrolase 44 protein 20100607 {GO:0005515=IPI, GO:0090231=IMP, GO:0006511=IEA, GO:0016579=IDA, GO:0004843=IDA, GO:0051322=IMP, GO:0090266=ISS, GO:0060564=IMP, GO:0005634=IDA, GO:0007067=IEA, GO:0008270=IEA, GO:0043161=ISS, GO:0004221=IMP, GO:0008234=IEA, GO:0051301=IEA} anaphase, cell division, mitosis, negative regulation of mitotic anaphase-promoting complex activity, proteasomal ubiquitin-dependent protein catabolic process, protein deubiquitination, regulation of mitotic cell cycle spindle assembly checkpoint, regulation of spindle checkpoint, ubiquitin-dependent protein catabolic process nucleus cysteine-type peptidase activity, protein binding, ubiquitin thiolesterase activity, ubiquitin-specific protease activity, zinc ion binding Human USP45 UniProtKB UniProtKB {GO:0006511=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0008234=GO_REF:0000037, GO:0004221=GO_REF:0000002} Q70EL2 Ubiquitin carboxyl-terminal hydrolase 45 protein 20130413 {GO:0006511=IEA, GO:0008270=IEA, GO:0008234=IEA, GO:0004221=IEA} ubiquitin-dependent protein catabolic process cysteine-type peptidase activity, ubiquitin thiolesterase activity, zinc ion binding Human UniProtKB-KW:KW-0788 USP46 UniProtKB UniProtKB {GO:0005515=PMID:19075014, GO:0006511=GO_REF:0000002, GO:0016579=PMID:19075014, GO:0004843=PMID:19075014, GO:0032228=GO_REF:0000024, GO:0007610=GO_REF:0000024, GO:0004221=PMID:19075014} P62068 Ubiquitin carboxyl-terminal hydrolase 46 protein 20090529 {GO:0005515=IPI, GO:0006511=IEA, GO:0016579=IDA, GO:0004843=IDA, GO:0032228=ISS, GO:0007610=ISS, GO:0004221=IDA} behavior, protein deubiquitination, regulation of synaptic transmission, GABAergic, ubiquitin-dependent protein catabolic process protein binding, ubiquitin thiolesterase activity, ubiquitin-specific protease activity Human UniProtKB:P62069 USP47 UniProtKB UniProtKB {GO:0005515=PMID:21362556, GO:0006511=GO_REF:0000002, GO:0043066=PMID:19966869, GO:0004843=PMID:21362556, GO:0030307=PMID:19966869, GO:0042493=PMID:19966869, GO:0006974=PMID:21362556, GO:0005737=PMID:21362556, GO:0034644=PMID:19966869, GO:0010972=PMID:19966869, GO:0071987=PMID:19966869, GO:0006284=PMID:21362556, GO:0035520=PMID:21362556, GO:0004221=GO_REF:0000002, GO:0008234=GO_REF:0000038, GO:0043154=PMID:19966869, GO:0045892=PMID:19966869, GO:0019005=PMID:19966869} Q96K76 Ubiquitin carboxyl-terminal hydrolase 47 protein 20110316 {GO:0005515=IPI, GO:0006511=IEA, GO:0043066=IMP, GO:0004843=IDA, GO:0030307=IMP, GO:0042493=IMP, GO:0006974=IMP, GO:0005737=IDA, GO:0034644=ISS, GO:0010972=IMP, GO:0071987=IPI, GO:0006284=IMP, GO:0035520=IDA, GO:0004221=IEA, GO:0008234=IEA, GO:0043154=IMP, GO:0045892=IMP, GO:0019005=IDA} base-excision repair, cellular response to UV, monoubiquitinated protein deubiquitination, negative regulation of G2/M transition of mitotic cell cycle, negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of transcription, DNA-dependent, positive regulation of cell growth, response to DNA damage stimulus, response to drug, ubiquitin-dependent protein catabolic process SCF ubiquitin ligase complex, cytoplasm WD40-repeat domain binding, cysteine-type peptidase activity, protein binding, ubiquitin thiolesterase activity, ubiquitin-specific protease activity Human UniProtKB:P06746 USP48 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0006511=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008234=GO_REF:0000037, GO:0004221=GO_REF:0000002} Q86UV5 Ubiquitin carboxyl-terminal hydrolase 48 protein 20101115 {GO:0005739=IDA, GO:0006511=IEA, GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0008234=IEA, GO:0004221=IEA} ubiquitin-dependent protein catabolic process cytoplasm, mitochondrion, nucleolus, nucleus cysteine-type peptidase activity, ubiquitin thiolesterase activity Human USP49 HPA UniProtKB {GO:0006511=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0008234=GO_REF:0000037, GO:0004221=GO_REF:0000002} Q70CQ1 Ubiquitin carboxyl-terminal hydrolase 49 protein 20101115 {GO:0006511=IEA, GO:0005737=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0008234=IEA, GO:0004221=IEA} ubiquitin-dependent protein catabolic process cytoplasm, nucleus cysteine-type peptidase activity, ubiquitin thiolesterase activity, zinc ion binding Human USP5 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0004197=PMID:7578059, GO:0071108=PMID:19098288, GO:0006511=GO_REF:0000002, GO:0032436=PMID:19098288, GO:0008270=GO_REF:0000002, GO:0008242=GO_REF:0000002, GO:0004221=GO_REF:0000002, GO:0005764=PMID:9827704} P45974 Ubiquitin carboxyl-terminal hydrolase 5 protein 20130415 {GO:0005515=IPI, GO:0004197=TAS, GO:0071108=IMP, GO:0006511=IEA, GO:0032436=IMP, GO:0008270=IEA, GO:0008242=IEA, GO:0004221=IEA, GO:0005764=TAS} positive regulation of proteasomal ubiquitin-dependent protein catabolic process, protein K48-linked deubiquitination, ubiquitin-dependent protein catabolic process lysosome cysteine-type endopeptidase activity, omega peptidase activity, protein binding, ubiquitin thiolesterase activity, zinc ion binding Human UniProtKB:O75528 USP50 InterPro UniProtKB {GO:0006511=GO_REF:0000002, GO:0004221=GO_REF:0000002} Q70EL3 Inactive ubiquitin carboxyl-terminal hydrolase 50 protein 20130413 {GO:0006511=IEA, GO:0004221=IEA} ubiquitin-dependent protein catabolic process ubiquitin thiolesterase activity Human InterPro:IPR001394|InterPro:IPR018200 USP51 UniProtKB UniProtKB {GO:0006511=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0008234=GO_REF:0000037, GO:0004221=GO_REF:0000002} Q70EK9 Ubiquitin carboxyl-terminal hydrolase 51 protein 20130413 {GO:0006511=IEA, GO:0008270=IEA, GO:0008234=IEA, GO:0004221=IEA} ubiquitin-dependent protein catabolic process cysteine-type peptidase activity, ubiquitin thiolesterase activity, zinc ion binding Human UniProtKB-KW:KW-0788 USP53 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0006511=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0004221=PMID:14715245} Q70EK8 Inactive ubiquitin carboxyl-terminal hydrolase 53 protein 20061026 {GO:0008150=ND, GO:0006511=IEA, GO:0005575=ND, GO:0004221=IDA} biological_process, ubiquitin-dependent protein catabolic process cellular_component ubiquitin thiolesterase activity Human USP54 IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0006511=GO_REF:0000002, GO:0004221=GO_REF:0000002} Q70EL1 Inactive ubiquitin carboxyl-terminal hydrolase 54 protein 20130415 {GO:0005515=IPI, GO:0006511=IEA, GO:0004221=IEA} ubiquitin-dependent protein catabolic process protein binding, ubiquitin thiolesterase activity Human UniProtKB:P54253 USP6 PINC UniProtKB {GO:0005515=PMID:15509780, GO:0006511=GO_REF:0000002, GO:0005516=PMID:16127172, GO:0016579=PMID:16127172, GO:0004843=PMID:16127172, GO:0005886=PMID:12612085, GO:0003676=PMID:1565468, GO:0005764=PMID:9827704, GO:0004197=PMID:9827704, GO:0005737=PMID:12612085, GO:0004221=GO_REF:0000002, GO:0060627=PMID:15509780, GO:0055037=PMID:15509780, GO:0005097=GO_REF:0000002, GO:0006464=PMID:9827704} P35125 Ubiquitin carboxyl-terminal hydrolase 6 protein 20031119 {GO:0005515=IPI, GO:0006511=IEA, GO:0005516=IPI, GO:0016579=IDA, GO:0004843=IDA, GO:0005886=IDA, GO:0003676=TAS, GO:0005764=TAS, GO:0004197=TAS, GO:0005737=IDA, GO:0004221=IEA, GO:0060627=IDA, GO:0055037=IDA, GO:0005097=IEA, GO:0006464=NAS} cellular protein modification process, protein deubiquitination, regulation of vesicle-mediated transport, ubiquitin-dependent protein catabolic process cytoplasm, lysosome, plasma membrane, recycling endosome Rab GTPase activator activity, calmodulin binding, cysteine-type endopeptidase activity, nucleic acid binding, protein binding, ubiquitin thiolesterase activity, ubiquitin-specific protease activity Human USP6NL GOC UniProtKB {GO:0035526=PMID:17684057, GO:0005794=GO_REF:0000039, GO:0007030=PMID:17684057, GO:0032851=PMID:17684057, GO:0016023=GO_REF:0000039, GO:0031410=PMID:17684057, GO:0005097=PMID:17684057} Q92738 USP6 N-terminal-like protein protein 20130413 {GO:0035526=IMP, GO:0005794=IEA, GO:0007030=IMP, GO:0032851=IDA, GO:0016023=IEA, GO:0031410=IDA, GO:0005097=IDA} Golgi organization, positive regulation of Rab GTPase activity, retrograde transport, plasma membrane to Golgi Golgi apparatus, cytoplasmic membrane-bounded vesicle, cytoplasmic vesicle Rab GTPase activator activity Human USP7 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0006511=GO_REF:0000002, GO:0016579=PMID:21745816, GO:0004843=PMID:21745816, GO:0032088=PMID:11279055, GO:0005634=PMID:11279055, GO:0007275=GO_REF:0000037, GO:0008022=PMID:12093161, GO:0005829=PMID:11279055, GO:0004197=PMID:21745816, GO:0002039=PMID:20096447, GO:0051090=PMID:16964248, GO:0010216=PMID:21745816, GO:0005737=GO_REF:0000019, GO:0006283=PMID:22466612, GO:0019048=GO_REF:0000037, GO:0016605=GO_REF:0000039, GO:0004221=PMID:21745816, GO:0008234=GO_REF:0000038, GO:0031625=PMID:11279055, GO:0008134=PMID:16964248} Q93009 Ubiquitin carboxyl-terminal hydrolase 7 protein 20130415 {GO:0005515=IPI, GO:0006511=IEA, GO:0016579=IDA, GO:0004843=IDA, GO:0032088=IDA, GO:0005634=IDA, GO:0007275=IEA, GO:0008022=IPI, GO:0005829=IDA, GO:0004197=IMP, GO:0002039=IDA, GO:0051090=IDA, GO:0010216=IMP, GO:0005737=IEA, GO:0006283=IMP, GO:0019048=IEA, GO:0016605=IEA, GO:0004221=IDA, GO:0008234=IEA, GO:0031625=IPI, GO:0008134=IPI} maintenance of DNA methylation, multicellular organismal development, negative regulation of NF-kappaB transcription factor activity, protein deubiquitination, regulation of sequence-specific DNA binding transcription factor activity, transcription-coupled nucleotide-excision repair, ubiquitin-dependent protein catabolic process, virus-host interaction PML body, cytoplasm, cytosol, nucleus cysteine-type endopeptidase activity, cysteine-type peptidase activity, p53 binding, protein C-terminus binding, protein binding, transcription factor binding, ubiquitin protein ligase binding, ubiquitin thiolesterase activity, ubiquitin-specific protease activity Human UniProtKB:Q99836 USP8 IntAct UniProtKB {GO:0005515=PMID:17711858, GO:0071108=PMID:16520378, GO:0006511=GO_REF:0000002, GO:0016579=PMID:18388320, GO:0017124=GO_REF:0000037, GO:0004843=PMID:18388320, GO:0008283=PMID:9628861, GO:0000281=PMID:18388320, GO:0030496=PMID:18388320, GO:0007265=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0005829=Reactome:REACT_116151, GO:0004197=PMID:9827704, GO:0005622=GO_REF:0000019, GO:0005737=PMID:18388320, GO:0070536=PMID:16520378, GO:0007032=PMID:16520378, GO:0004221=GO_REF:0000002, GO:0008234=GO_REF:0000038, GO:0019897=PMID:16520378, GO:0010008=GO_REF:0000039, GO:0005769=PMID:16520378} P40818 Ubiquitin carboxyl-terminal hydrolase 8 protein 20130415 {GO:0005515=IPI, GO:0071108=IDA, GO:0006511=IEA, GO:0016579=IMP, GO:0017124=IEA, GO:0004843=IDA, GO:0008283=TAS, GO:0000281=IMP, GO:0030496=IDA, GO:0007265=IEA, GO:0005634=IEA, GO:0005829=TAS, GO:0004197=TAS, GO:0005622=IEA, GO:0005737=IDA, GO:0070536=IDA, GO:0007032=IMP, GO:0004221=IEA, GO:0008234=IEA, GO:0019897=IDA, GO:0010008=IEA, GO:0005769=IDA} Ras protein signal transduction, cell proliferation, cytokinesis after mitosis, endosome organization, protein K48-linked deubiquitination, protein K63-linked deubiquitination, protein deubiquitination, ubiquitin-dependent protein catabolic process cytoplasm, cytosol, early endosome, endosome membrane, extrinsic to plasma membrane, intracellular, midbody, nucleus SH3 domain binding, cysteine-type endopeptidase activity, cysteine-type peptidase activity, protein binding, ubiquitin thiolesterase activity, ubiquitin-specific protease activity Human UniProtKB:Q9HD42 USP9X BHF-UCL UniProtKB {GO:0005515=PMID:16322459, GO:0010467=Reactome:REACT_71, GO:0006511=GO_REF:0000002, GO:0016579=PMID:19135894, GO:0006367=Reactome:REACT_12627, GO:0070410=PMID:19135894, GO:0045177=GO_REF:0000019, GO:0000122=Reactome:REACT_121111, GO:0030509=PMID:19135894, GO:0007292=PMID:8922996, GO:0006351=Reactome:REACT_121061, GO:0005829=Reactome:REACT_121227, GO:0004197=PMID:9827704, GO:0007067=GO_REF:0000037, GO:0005737=PMID:19135894, GO:0007059=GO_REF:0000037, GO:0007179=Reactome:REACT_6844, GO:0004221=Reactome:REACT_120856, GO:0008234=PMID:8922996, GO:0051301=GO_REF:0000037} Q93008 Probable ubiquitin carboxyl-terminal hydrolase FAF-X protein 20090325 {GO:0005515=IPI, GO:0010467=TAS, GO:0006511=IEA, GO:0016579=IDA, GO:0006367=TAS, GO:0070410=IPI, GO:0045177=IEA, GO:0000122=TAS, GO:0030509=IDA, GO:0007292=TAS, GO:0006351=TAS, GO:0005829=TAS, GO:0004197=TAS, GO:0007067=IEA, GO:0005737=IDA, GO:0007059=IEA, GO:0007179=TAS, GO:0004221=TAS, GO:0008234=TAS, GO:0051301=IEA} BMP signaling pathway, cell division, chromosome segregation, female gamete generation, gene expression, mitosis, negative regulation of transcription from RNA polymerase II promoter, protein deubiquitination, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway, ubiquitin-dependent protein catabolic process apical part of cell, cytoplasm, cytosol co-SMAD binding, cysteine-type endopeptidase activity, cysteine-type peptidase activity, protein binding, ubiquitin thiolesterase activity Human UniProtKB:Q13485 USP9Y BHF-UCL UniProtKB {GO:0006511=GO_REF:0000002, GO:0016579=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0004843=PMID:9384609, GO:0070410=GO_REF:0000024, GO:0007179=GO_REF:0000024, GO:0008234=PMID:8922996, GO:0007283=PMID:9384609, GO:0030509=GO_REF:0000024, GO:0004221=GO_REF:0000002} O00507 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y protein 20090325 {GO:0006511=IEA, GO:0016579=ISS, GO:0005737=ISS, GO:0004843=TAS, GO:0070410=ISS, GO:0007179=ISS, GO:0008234=TAS, GO:0007283=TAS, GO:0030509=ISS, GO:0004221=IEA} BMP signaling pathway, protein deubiquitination, spermatogenesis, transforming growth factor beta receptor signaling pathway, ubiquitin-dependent protein catabolic process cytoplasm co-SMAD binding, cysteine-type peptidase activity, ubiquitin thiolesterase activity, ubiquitin-specific protease activity Human UniProtKB:Q93008 USPL1 UniProtKB UniProtKB {GO:0043130=PMID:22878415, GO:0030576=PMID:22878415, GO:0006511=GO_REF:0000002, GO:0032183=PMID:22878415, GO:0015030=PMID:22878415, GO:0008283=PMID:22878415, GO:0016926=PMID:22878415, GO:0004221=GO_REF:0000002, GO:0070140=PMID:22878415} Q5W0Q7 SUMO-specific isopeptidase USPL1 protein 20120821 {GO:0043130=IDA, GO:0030576=IMP, GO:0006511=IEA, GO:0032183=IDA, GO:0015030=IDA, GO:0008283=IMP, GO:0016926=IDA, GO:0004221=IEA, GO:0070140=IDA} Cajal body organization, cell proliferation, protein desumoylation, ubiquitin-dependent protein catabolic process Cajal body SUMO binding, SUMO-specific isopeptidase activity, ubiquitin binding, ubiquitin thiolesterase activity Human UST Reactome UniProtKB {GO:0030208=Reactome:REACT_120800, GO:0000139=Reactome:REACT_120932, GO:0005975=Reactome:REACT_474, GO:0008146=GO_REF:0000002, GO:0006477=PMID:10187838, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121315} Q9Y2C2 Uronyl 2-sulfotransferase protein 20130301 {GO:0030208=TAS, GO:0000139=TAS, GO:0005975=TAS, GO:0008146=IEA, GO:0006477=TAS, GO:0044281=TAS, GO:0016021=IEA, GO:0030204=TAS, GO:0030203=TAS} carbohydrate metabolic process, chondroitin sulfate metabolic process, dermatan sulfate biosynthetic process, glycosaminoglycan metabolic process, protein sulfation, small molecule metabolic process Golgi membrane, integral to membrane sulfotransferase activity Human UTF1 PINC UniProtKB {GO:0005515=PMID:9748258, GO:0006357=PMID:9748258, GO:0045944=PMID:9748258, GO:0003713=PMID:9748258, GO:0071837=GO_REF:0000019, GO:0005634=PMID:18281244, GO:0008584=PMID:18281244, GO:0006351=GO_REF:0000037} Q5T230 Undifferentiated embryonic cell transcription factor 1 protein 20070906 {GO:0005515=IPI, GO:0006357=TAS, GO:0045944=IDA, GO:0003713=IDA, GO:0071837=IEA, GO:0005634=IDA, GO:0008584=IEP, GO:0006351=IEA} male gonad development, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus HMG box domain binding, protein binding, transcription coactivator activity Human UTP11L HGNC UniProtKB {GO:0005515=PMID:12559088, GO:0005737=PMID:12559088, GO:0048011=PMID:12559088, GO:0006364=GO_REF:0000037, GO:0032040=GO_REF:0000002, GO:0005730=GO_REF:0000039, GO:0005634=PMID:12559088, GO:0006917=PMID:12559088, GO:0005615=PMID:12559088, GO:0007399=PMID:12559088} Q9Y3A2 Probable U3 small nucleolar RNA-associated protein 11 protein 20050610 {GO:0005515=IPI, GO:0005737=IDA, GO:0048011=IMP, GO:0006364=IEA, GO:0032040=IEA, GO:0005730=IEA, GO:0005634=IDA, GO:0006917=IMP, GO:0005615=IDA, GO:0007399=IMP} induction of apoptosis, nervous system development, neurotrophin TRK receptor signaling pathway, rRNA processing cytoplasm, extracellular space, nucleolus, nucleus, small-subunit processome protein binding Human UniProtKB:P35609 UTP14A IntAct UniProtKB {GO:0005515=PMID:15383276, GO:0006364=GO_REF:0000002, GO:0032040=GO_REF:0000002, GO:0005730=GO_REF:0000039} Q9BVJ6 U3 small nucleolar RNA-associated protein 14 homolog A protein 20130415 {GO:0005515=IPI, GO:0006364=IEA, GO:0032040=IEA, GO:0005730=IEA} rRNA processing nucleolus, small-subunit processome protein binding Human UniProtKB:O95257 UTP15 LIFEdb UniProtKB {GO:0005737=GO_REF:0000054, GO:0006364=GO_REF:0000037, GO:0005730=GO_REF:0000039} Q8TED0 U3 small nucleolar RNA-associated protein 15 homolog protein 20100607 {GO:0005737=IDA, GO:0006364=IEA, GO:0005730=IEA} rRNA processing cytoplasm, nucleolus Human UTP18 UniProtKB UniProtKB {GO:0006364=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0005634=PMID:15199122} Q9Y5J1 U3 small nucleolar RNA-associated protein 18 homolog protein 20050603 {GO:0006364=IEA, GO:0005730=IEA, GO:0005634=IDA} rRNA processing nucleolus, nucleus Human UTP20 PINC UniProtKB {GO:0005515=PMID:17498821, GO:0000472=PMID:17652137, GO:0005737=PMID:17652137, GO:0008285=PMID:9673349, GO:0006364=PMID:17498821, GO:0032040=PMID:15590835, GO:0005730=PMID:15590835, GO:0000480=PMID:17652137, GO:0005654=PMID:17652137, GO:0000447=PMID:15590835, GO:0030688=PMID:17652137, GO:0030686=PMID:12150911} O75691 Small subunit processome component 20 homolog protein 20030904 {GO:0005515=IPI, GO:0000472=ISS, GO:0005737=ISS, GO:0008285=TAS, GO:0006364=IMP, GO:0032040=ISS, GO:0005730=ISS, GO:0000480=ISS, GO:0005654=ISS, GO:0000447=ISS, GO:0030688=ISS, GO:0030686=ISS} endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA), negative regulation of cell proliferation, rRNA processing 90S preribosome, cytoplasm, nucleolus, nucleoplasm, preribosome, small subunit precursor, small-subunit processome protein binding Human UTP23 UniProtKB UniProtKB {GO:0006364=GO_REF:0000037, GO:0005730=GO_REF:0000039} Q9BRU9 rRNA-processing protein UTP23 homolog protein 20130413 {GO:0006364=IEA, GO:0005730=IEA} rRNA processing nucleolus Human UniProtKB-SubCell:SL-0188 UTP3 LIFEdb UniProtKB {GO:0003674=GO_REF:0000015, GO:0007420=GO_REF:0000024, GO:0005730=GO_REF:0000054, GO:0005634=GO_REF:0000024, GO:0016568=GO_REF:0000037} Q9NQZ2 Something about silencing protein 10 protein 20100607 {GO:0003674=ND, GO:0007420=ISS, GO:0005730=IDA, GO:0005634=ISS, GO:0016568=IEA} brain development, chromatin modification nucleolus, nucleus molecular_function Human UTP6 HPA UniProtKB {GO:0006364=GO_REF:0000037, GO:0005730=GO_REF:0000052} Q9NYH9 U3 small nucleolar RNA-associated protein 6 homolog protein 20111111 {GO:0006364=IEA, GO:0005730=IDA} rRNA processing nucleolus Human UTRN InterPro UniProtKB {GO:0005515=PMID:10767429, GO:0030054=GO_REF:0000037, GO:0031594=GO_REF:0000019, GO:0005886=GO_REF:0000052, GO:0005509=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0003779=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0043234=PMID:18468998, GO:0005737=PMID:19786618, GO:0007517=PMID:9288751, GO:0006936=PMID:9288751, GO:0016010=GO_REF:0000019, GO:0016020=PMID:1426262, GO:0045211=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0005856=GO_REF:0000039, GO:0001954=PMID:19786618} Q5T097 Utrophin protein 20130413 {GO:0005515=IPI, GO:0030054=IEA, GO:0031594=IEA, GO:0005886=IDA, GO:0005509=IEA, GO:0005730=IDA, GO:0003779=IEA, GO:0005634=IDA, GO:0043234=IDA, GO:0005737=IDA, GO:0007517=TAS, GO:0006936=TAS, GO:0016010=IEA, GO:0016020=TAS, GO:0045211=IEA, GO:0008270=IEA, GO:0005856=IEA, GO:0001954=IMP} muscle contraction, muscle organ development, positive regulation of cell-matrix adhesion cell junction, cytoplasm, cytoskeleton, dystrophin-associated glycoprotein complex, membrane, neuromuscular junction, nucleolus, nucleus, plasma membrane, postsynaptic membrane, protein complex actin binding, calcium ion binding, protein binding, zinc ion binding Human InterPro:IPR000433 UTS2 Reactome UniProtKB {GO:0046005=GO_REF:0000019, GO:0045597=GO_REF:0000019, GO:0007268=PMID:10499587, GO:0045776=GO_REF:0000019, GO:0048146=GO_REF:0000019, GO:0045777=GO_REF:0000019, GO:0007204=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:0010763=GO_REF:0000019, GO:0006936=PMID:10499587, GO:0045909=GO_REF:0000019, GO:0046676=GO_REF:0000019, GO:0010459=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0005102=PMID:10499587, GO:0005576=Reactome:REACT_22436, GO:0010841=GO_REF:0000019, GO:0033574=GO_REF:0000019, GO:0003105=GO_REF:0000019, GO:0045766=GO_REF:0000019, GO:0032224=GO_REF:0000019, GO:0032967=GO_REF:0000019, GO:0005179=GO_REF:0000037, GO:0008217=PMID:10499587, GO:0035814=GO_REF:0000019, GO:0035811=GO_REF:0000019, GO:0010460=GO_REF:0000019} O95399 Urotensin-2 protein 20091027 {GO:0046005=IEA, GO:0045597=IEA, GO:0007268=TAS, GO:0045776=IEA, GO:0048146=IEA, GO:0045777=IEA, GO:0007204=IEA, GO:0005615=IEA, GO:0010763=IEA, GO:0006936=TAS, GO:0045909=IEA, GO:0046676=IEA, GO:0010459=IEA, GO:0001666=IEA, GO:0042493=IEA, GO:0005102=TAS, GO:0005576=TAS, GO:0010841=IEA, GO:0033574=IEA, GO:0003105=IEA, GO:0045766=IEA, GO:0032224=IEA, GO:0032967=IEA, GO:0005179=IEA, GO:0008217=TAS, GO:0035814=IEA, GO:0035811=IEA, GO:0010460=IEA} elevation of cytosolic calcium ion concentration, muscle contraction, negative regulation of blood pressure, negative regulation of glomerular filtration, negative regulation of heart rate, negative regulation of insulin secretion, negative regulation of renal sodium excretion, negative regulation of urine volume, positive regulation of angiogenesis, positive regulation of blood pressure, positive regulation of cell differentiation, positive regulation of circadian sleep/wake cycle, REM sleep, positive regulation of circadian sleep/wake cycle, wakefulness, positive regulation of collagen biosynthetic process, positive regulation of fibroblast migration, positive regulation of fibroblast proliferation, positive regulation of heart rate, positive regulation of synaptic transmission, cholinergic, positive regulation of vasodilation, regulation of blood pressure, response to drug, response to hypoxia, response to testosterone stimulus, synaptic transmission extracellular region, extracellular space hormone activity, receptor binding Human UTS2R Reactome UniProtKB {GO:0005886=Reactome:REACT_22436, GO:0004930=PMID:10499587, GO:0046005=GO_REF:0000019, GO:0030307=GO_REF:0000019, GO:0008015=PMID:10499587, GO:0042493=GO_REF:0000019, GO:0048146=GO_REF:0000019, GO:0010841=GO_REF:0000019, GO:0045776=GO_REF:0000019, GO:0045777=GO_REF:0000019, GO:0003105=GO_REF:0000019, GO:0007204=GO_REF:0000019, GO:0045766=GO_REF:0000019, GO:0007165=PMID:10499587, GO:0042312=GO_REF:0000002, GO:0016020=PMID:8666380, GO:0045907=GO_REF:0000019, GO:0035814=GO_REF:0000019, GO:0001604=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0035811=GO_REF:0000019, GO:0055037=GO_REF:0000019, GO:0005769=GO_REF:0000019} Q9UKP6 Urotensin-2 receptor protein 20100217 {GO:0005886=TAS, GO:0004930=TAS, GO:0046005=IEA, GO:0030307=IEA, GO:0008015=TAS, GO:0042493=IEA, GO:0048146=IEA, GO:0010841=IEA, GO:0045776=IEA, GO:0045777=IEA, GO:0003105=IEA, GO:0007204=IEA, GO:0045766=IEA, GO:0007165=TAS, GO:0042312=IEA, GO:0016020=TAS, GO:0045907=IEA, GO:0035814=IEA, GO:0001604=IEA, GO:0016021=IEA, GO:0035811=IEA, GO:0055037=IEA, GO:0005769=IEA} blood circulation, elevation of cytosolic calcium ion concentration, negative regulation of blood pressure, negative regulation of glomerular filtration, negative regulation of renal sodium excretion, negative regulation of urine volume, positive regulation of angiogenesis, positive regulation of blood pressure, positive regulation of cell growth, positive regulation of circadian sleep/wake cycle, REM sleep, positive regulation of circadian sleep/wake cycle, wakefulness, positive regulation of fibroblast proliferation, positive regulation of vasoconstriction, regulation of vasodilation, response to drug, signal transduction early endosome, integral to membrane, membrane, plasma membrane, recycling endosome G-protein coupled receptor activity, urotensin II receptor activity Human UTY UniProtKB UniProtKB {GO:0007507=GO_REF:0000019, GO:0031935=GO_REF:0000019, GO:0086003=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0016702=GO_REF:0000037, GO:0001701=GO_REF:0000019, GO:0051864=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0045184=GO_REF:0000019} O14607 Histone demethylase UTY protein 20130413 {GO:0007507=IEA, GO:0031935=IEA, GO:0086003=IEA, GO:0005634=IEA, GO:0016702=IEA, GO:0001701=IEA, GO:0051864=IEA, GO:0046872=IEA, GO:0045184=IEA} cardiac muscle cell contraction, establishment of protein localization, heart development, in utero embryonic development, regulation of chromatin silencing nucleus histone demethylase activity (H3-K36 specific), metal ion binding, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Human UniProtKB-SubCell:SL-0191 UVRAG BHF-UCL UniProtKB {GO:0005515=PMID:22354037, GO:0043234=GO_REF:0000019, GO:0005737=PMID:9169138, GO:0017124=GO_REF:0000019, GO:0006281=PMID:9169138, GO:0005770=PMID:19270696, GO:0005764=PMID:19270696, GO:0005769=PMID:19270696, GO:0010508=GO_REF:0000002} Q9P2Y5 UV radiation resistance-associated gene protein protein 20120531 {GO:0005515=IPI, GO:0043234=IEA, GO:0005737=TAS, GO:0017124=IEA, GO:0006281=TAS, GO:0005770=IDA, GO:0005764=IDA, GO:0005769=IDA, GO:0010508=IEA} DNA repair, positive regulation of autophagy cytoplasm, early endosome, late endosome, lysosome, protein complex SH3 domain binding, protein binding Human UniProtKB:Q9Y250 UXS1 UniPathway UniProtKB {GO:0005739=GO_REF:0000019, GO:0050662=GO_REF:0000002, GO:0032580=GO_REF:0000039, GO:0033320=GO_REF:0000041, GO:0048040=GO_REF:0000003, GO:0016021=GO_REF:0000037, GO:0003824=GO_REF:0000002, GO:0044237=GO_REF:0000002} Q8NBZ7 UDP-glucuronic acid decarboxylase 1 protein 20130413 {GO:0005739=IEA, GO:0050662=IEA, GO:0032580=IEA, GO:0033320=IEA, GO:0048040=IEA, GO:0016021=IEA, GO:0003824=IEA, GO:0044237=IEA} UDP-D-xylose biosynthetic process, cellular metabolic process Golgi cisterna membrane, integral to membrane, mitochondrion UDP-glucuronate decarboxylase activity, catalytic activity, coenzyme binding Human UniPathway:UPA00796 UXT IntAct UniProtKB {GO:0008017=PMID:12762840, GO:0005515=PMID:17635584, GO:0005813=PMID:16221885, GO:0001106=PMID:21730289, GO:0016272=GO_REF:0000002, GO:0048487=PMID:12762840, GO:0000226=PMID:16221885, GO:0005634=PMID:12762840, GO:0000122=PMID:21730289, GO:0051297=PMID:16221885, GO:0005737=PMID:21730289, GO:0051015=PMID:12762840, GO:0047497=PMID:12762840, GO:0006457=GO_REF:0000002, GO:0003682=PMID:21730289, GO:0000930=PMID:16221885, GO:0051082=GO_REF:0000002, GO:0005856=PMID:12762840} Q9UBK9 Protein UXT protein 20130415 {GO:0008017=TAS, GO:0005515=IPI, GO:0005813=IDA, GO:0001106=IDA, GO:0016272=IEA, GO:0048487=IDA, GO:0000226=IMP, GO:0005634=IDA, GO:0000122=IDA, GO:0051297=IMP, GO:0005737=IDA, GO:0051015=IDA, GO:0047497=TAS, GO:0006457=IEA, GO:0003682=IDA, GO:0000930=IDA, GO:0051082=IEA, GO:0005856=IDA} centrosome organization, microtubule cytoskeleton organization, mitochondrion transport along microtubule, negative regulation of transcription from RNA polymerase II promoter, protein folding centrosome, cytoplasm, cytoskeleton, gamma-tubulin complex, nucleus, prefoldin complex RNA polymerase II transcription corepressor activity, actin filament binding, beta-tubulin binding, chromatin binding, microtubule binding, protein binding, unfolded protein binding Human UniProtKB:Q03112 VAC14 Reactome UniProtKB {GO:0007165=PMID:8611628, GO:0019209=GO_REF:0000002, GO:0006661=Reactome:REACT_120918, GO:0000139=Reactome:REACT_121149, GO:0005783=GO_REF:0000037, GO:0031901=Reactome:REACT_121095, GO:0019048=GO_REF:0000037, GO:0031902=Reactome:REACT_121351, GO:0004872=PMID:8611628, GO:0044281=Reactome:REACT_111217, GO:0006644=Reactome:REACT_121175, GO:0010008=PMID:17556371} Q08AM6 Protein VAC14 homolog protein 20111102 {GO:0007165=NAS, GO:0019209=IEA, GO:0006661=TAS, GO:0000139=TAS, GO:0005783=IEA, GO:0031901=TAS, GO:0019048=IEA, GO:0031902=TAS, GO:0004872=NAS, GO:0044281=TAS, GO:0006644=TAS, GO:0010008=IDA} phosphatidylinositol biosynthetic process, phospholipid metabolic process, signal transduction, small molecule metabolic process, virus-host interaction Golgi membrane, early endosome membrane, endoplasmic reticulum, endosome membrane, late endosome membrane kinase activator activity, receptor activity Human VAMP1 Reactome UniProtKB {GO:0030666=Reactome:REACT_11179, GO:0005515=PMID:9920726, GO:0043005=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0005887=PMID:1976629, GO:0007268=Reactome:REACT_13685, GO:0030672=GO_REF:0000039, GO:0005741=GO_REF:0000039, GO:0016021=GO_REF:0000002, GO:0016192=GO_REF:0000002, GO:0007269=Reactome:REACT_11184} P23763 Vesicle-associated membrane protein 1 protein 20130109 {GO:0030666=TAS, GO:0005515=IPI, GO:0043005=IEA, GO:0030054=IEA, GO:0005887=TAS, GO:0007268=TAS, GO:0030672=IEA, GO:0005741=IEA, GO:0016021=IEA, GO:0016192=IEA, GO:0007269=TAS} neurotransmitter secretion, synaptic transmission, vesicle-mediated transport cell junction, endocytic vesicle membrane, integral to membrane, integral to plasma membrane, mitochondrial outer membrane, neuron projection, synaptic vesicle membrane protein binding Human VAMP2 IntAct UniProtKB {GO:0005515=PMID:22118466, GO:0070083=Reactome:REACT_15533, GO:0043005=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_23813, GO:0030136=PMID:19478182, GO:0006892=Reactome:REACT_11235, GO:0031201=PMID:19546860, GO:0007268=Reactome:REACT_13685, GO:0044281=Reactome:REACT_111217, GO:0014047=Reactome:REACT_12591, GO:0060203=Reactome:REACT_15483, GO:0007269=Reactome:REACT_13723, GO:0030666=Reactome:REACT_11179, GO:0006112=Reactome:REACT_1505, GO:0050796=Reactome:REACT_18325, GO:0005887=PMID:1976629, GO:0030672=GO_REF:0000039, GO:0061202=Reactome:REACT_23973, GO:0016021=GO_REF:0000002, GO:0016192=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0016044=Reactome:REACT_11123, GO:0030667=Reactome:REACT_14822} P63027 Vesicle-associated membrane protein 2 protein 20130415 {GO:0005515=IPI, GO:0070083=TAS, GO:0043005=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0030136=IDA, GO:0006892=TAS, GO:0031201=IDA, GO:0007268=TAS, GO:0044281=TAS, GO:0014047=TAS, GO:0060203=TAS, GO:0007269=TAS, GO:0030666=TAS, GO:0006112=TAS, GO:0050796=TAS, GO:0005887=TAS, GO:0030672=IEA, GO:0061202=TAS, GO:0016021=IEA, GO:0016192=IEA, GO:0044267=TAS, GO:0016044=TAS, GO:0030667=TAS} cellular membrane organization, cellular protein metabolic process, energy reserve metabolic process, glutamate secretion, neurotransmitter secretion, post-Golgi vesicle-mediated transport, regulation of insulin secretion, small molecule metabolic process, synaptic transmission, vesicle-mediated transport SNARE complex, cell junction, clathrin-coated vesicle, clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane, clathrin-sculpted glutamate transport vesicle membrane, clathrin-sculpted monoamine transport vesicle membrane, endocytic vesicle membrane, integral to membrane, integral to plasma membrane, neuron projection, plasma membrane, secretory granule membrane, synaptic vesicle membrane protein binding Human UniProtKB:O55012 VAMP3 IntAct UniProtKB {GO:0005515=PMID:22118466, GO:0043005=GO_REF:0000039, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000024, GO:0043001=GO_REF:0000019, GO:0030136=PMID:19478182, GO:0045202=GO_REF:0000037, GO:0031201=GO_REF:0000019, GO:0006887=PMID:9885218, GO:0006904=PMID:9885218, GO:0030665=GO_REF:0000019, GO:0016324=GO_REF:0000019, GO:0006461=GO_REF:0000019, GO:0006944=PMID:9885218, GO:0017156=GO_REF:0000019, GO:0001921=GO_REF:0000024, GO:0034446=GO_REF:0000024, GO:0042147=PMID:18195106, GO:0016021=GO_REF:0000037, GO:0017075=GO_REF:0000019, GO:0055037=PMID:19061864, GO:0016192=GO_REF:0000024, GO:0030141=GO_REF:0000019} Q15836 Vesicle-associated membrane protein 3 protein 20130415 {GO:0005515=IPI, GO:0043005=IEA, GO:0030054=IEA, GO:0005886=ISS, GO:0043001=IEA, GO:0030136=IDA, GO:0045202=IEA, GO:0031201=IEA, GO:0006887=TAS, GO:0006904=TAS, GO:0030665=IEA, GO:0016324=IEA, GO:0006461=IEA, GO:0006944=TAS, GO:0017156=IEA, GO:0001921=ISS, GO:0034446=ISS, GO:0042147=IDA, GO:0016021=IEA, GO:0017075=IEA, GO:0055037=IDA, GO:0016192=ISS, GO:0030141=IEA} Golgi to plasma membrane protein transport, calcium ion-dependent exocytosis, cellular membrane fusion, exocytosis, positive regulation of receptor recycling, protein complex assembly, retrograde transport, endosome to Golgi, substrate adhesion-dependent cell spreading, vesicle docking involved in exocytosis, vesicle-mediated transport SNARE complex, apical plasma membrane, cell junction, clathrin-coated vesicle, clathrin-coated vesicle membrane, integral to membrane, neuron projection, plasma membrane, recycling endosome, secretory granule, synapse protein binding, syntaxin-1 binding Human UniProtKB:O55012 VAMP4 PINC UniProtKB {GO:0005802=GO_REF:0000019, GO:0000139=PMID:9553086, GO:0043001=GO_REF:0000019, GO:0042996=GO_REF:0000019, GO:0031201=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0005764=PMID:9553086, GO:0005768=PMID:9553086} O75379 Vesicle-associated membrane protein 4 protein 20030904 {GO:0005802=IEA, GO:0000139=TAS, GO:0043001=IEA, GO:0042996=IEA, GO:0031201=IEA, GO:0016021=IEA, GO:0005764=TAS, GO:0005768=TAS} Golgi to plasma membrane protein transport, regulation of Golgi to plasma membrane protein transport Golgi membrane, SNARE complex, endosome, integral to membrane, lysosome, trans-Golgi network Human VAMP5 PINC UniProtKB {GO:0005802=GO_REF:0000019, GO:0007517=PMID:9725904, GO:0005794=GO_REF:0000039, GO:0005886=PMID:9725904, GO:0043001=GO_REF:0000019, GO:0007519=GO_REF:0000019, GO:0005887=GO_REF:0000019, GO:0030154=GO_REF:0000037, GO:0012505=GO_REF:0000039} O95183 Vesicle-associated membrane protein 5 protein 20030904 {GO:0005802=IEA, GO:0007517=TAS, GO:0005794=IEA, GO:0005886=TAS, GO:0043001=IEA, GO:0007519=IEA, GO:0005887=IEA, GO:0030154=IEA, GO:0012505=IEA} Golgi to plasma membrane protein transport, cell differentiation, muscle organ development, skeletal muscle tissue development Golgi apparatus, endomembrane system, integral to plasma membrane, plasma membrane, trans-Golgi network Human VAMP7 HPA UniProtKB {GO:0005515=PMID:18775314, GO:0043005=GO_REF:0000024, GO:0048471=GO_REF:0000019, GO:0030054=GO_REF:0000037, GO:0005886=Reactome:REACT_14778, GO:0043001=GO_REF:0000019, GO:0043312=PMID:14993220, GO:0045202=GO_REF:0000037, GO:0031201=PMID:15133481, GO:0005765=Reactome:REACT_14778, GO:0006906=PMID:10888671, GO:0043231=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0017156=PMID:14993220, GO:0030670=GO_REF:0000039, GO:0016192=PMID:10888671, GO:0034197=GO_REF:0000019, GO:0030658=GO_REF:0000039, GO:0000046=PMID:23217709, GO:0019905=GO_REF:0000019, GO:0005794=GO_REF:0000052, GO:0008333=PMID:10888671, GO:0006892=Reactome:REACT_11235, GO:0045177=GO_REF:0000019, GO:0048280=GO_REF:0000019, GO:0006911=PMID:15133481, GO:0043308=PMID:14993220, GO:0045335=PMID:15470500, GO:0006888=PMID:16495485, GO:1900483=GO_REF:0000019, GO:0031902=PMID:10459012, GO:0005789=PMID:16495485, GO:0016021=GO_REF:0000037, GO:0016044=Reactome:REACT_11123} P51809 Vesicle-associated membrane protein 7 protein 20110516 {GO:0005515=IPI, GO:0043005=ISS, GO:0048471=IEA, GO:0030054=IEA, GO:0005886=TAS, GO:0043001=IEA, GO:0043312=ISS, GO:0045202=IEA, GO:0031201=ISS, GO:0005765=TAS, GO:0006906=IDA, GO:0043231=IDA, GO:0005737=IDA, GO:0017156=ISS, GO:0030670=IEA, GO:0016192=IDA, GO:0034197=IEA, GO:0030658=IEA, GO:0000046=IMP, GO:0019905=IEA, GO:0005794=IDA, GO:0008333=IDA, GO:0006892=TAS, GO:0045177=IEA, GO:0048280=IEA, GO:0006911=ISS, GO:0043308=ISS, GO:0045335=ISS, GO:0006888=ISS, GO:1900483=IEA, GO:0031902=ISS, GO:0005789=ISS, GO:0016021=IEA, GO:0016044=TAS} ER to Golgi vesicle-mediated transport, Golgi to plasma membrane protein transport, autophagic vacuole fusion, calcium ion-dependent exocytosis, cellular membrane organization, endosome to lysosome transport, eosinophil degranulation, neutrophil degranulation, phagocytosis, engulfment, post-Golgi vesicle-mediated transport, regulation of protein targeting to vacuolar membrane, triglyceride transport, vesicle fusion, vesicle fusion with Golgi apparatus, vesicle-mediated transport Golgi apparatus, SNARE complex, apical part of cell, cell junction, cytoplasm, endoplasmic reticulum membrane, integral to membrane, intracellular membrane-bounded organelle, late endosome membrane, lysosomal membrane, neuron projection, perinuclear region of cytoplasm, phagocytic vesicle, phagocytic vesicle membrane, plasma membrane, synapse, transport vesicle membrane protein binding, syntaxin binding Human VAMP8 Reactome UniProtKB {GO:0019905=GO_REF:0000019, GO:0000046=PMID:23217709, GO:0005886=Reactome:REACT_14821, GO:0006892=Reactome:REACT_11235, GO:0031201=PMID:23217709, GO:0005765=PMID:23217709, GO:0006906=GO_REF:0000019, GO:0005739=GO_REF:0000019, GO:0006461=GO_REF:0000019, GO:0016020=PMID:9614193, GO:0030100=GO_REF:0000019, GO:0031902=PMID:23217709, GO:0016021=GO_REF:0000037, GO:0055037=GO_REF:0000019, GO:0016192=GO_REF:0000002, GO:0030141=GO_REF:0000019, GO:0016044=Reactome:REACT_11123, GO:0005769=PMID:9614193, GO:0030667=Reactome:REACT_14821} Q9BV40 Vesicle-associated membrane protein 8 protein 20130220 {GO:0019905=IEA, GO:0000046=IMP, GO:0005886=TAS, GO:0006892=TAS, GO:0031201=IDA, GO:0005765=IDA, GO:0006906=IEA, GO:0005739=IEA, GO:0006461=IEA, GO:0016020=TAS, GO:0030100=IEA, GO:0031902=IDA, GO:0016021=IEA, GO:0055037=IEA, GO:0016192=IEA, GO:0030141=IEA, GO:0016044=TAS, GO:0005769=TAS, GO:0030667=TAS} autophagic vacuole fusion, cellular membrane organization, post-Golgi vesicle-mediated transport, protein complex assembly, regulation of endocytosis, vesicle fusion, vesicle-mediated transport SNARE complex, early endosome, integral to membrane, late endosome membrane, lysosomal membrane, membrane, mitochondrion, plasma membrane, recycling endosome, secretory granule, secretory granule membrane syntaxin binding Human VANGL1 IntAct UniProtKB {GO:0005515=PMID:15205336, GO:0007275=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q8TAA9 Vang-like protein 1 protein 20130415 {GO:0005515=IPI, GO:0007275=IEA, GO:0016021=IEA} multicellular organismal development integral to membrane protein binding Human UniProtKB:P27701 VANGL2 UniProtKB UniProtKB {GO:0001736=GO_REF:0000024, GO:0035787=GO_REF:0000024, GO:0048103=GO_REF:0000019, GO:0060122=GO_REF:0000019, GO:0007266=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0001947=GO_REF:0000024, GO:0060028=GO_REF:0000019, GO:0016323=GO_REF:0000019, GO:0016324=GO_REF:0000024, GO:0005911=GO_REF:0000024, GO:0032956=GO_REF:0000019, GO:0090103=GO_REF:0000019, GO:0043507=GO_REF:0000019, GO:0022007=GO_REF:0000019, GO:0035019=GO_REF:0000019, GO:0060187=GO_REF:0000019, GO:0001942=GO_REF:0000019, GO:0060490=GO_REF:0000019, GO:0003150=GO_REF:0000019, GO:0003402=GO_REF:0000019, GO:0090179=GO_REF:0000019, GO:0001843=GO_REF:0000024, GO:0045176=GO_REF:0000024, GO:0090177=GO_REF:0000019, GO:0035058=GO_REF:0000024, GO:0016328=GO_REF:0000024, GO:0048546=GO_REF:0000019, GO:0045197=GO_REF:0000019, GO:0060489=GO_REF:0000019, GO:0003149=GO_REF:0000019, GO:0060488=GO_REF:0000019, GO:0042060=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0048105=GO_REF:0000019} Q9ULK5 Vang-like protein 2 protein 20060707 {GO:0001736=ISS, GO:0035787=ISS, GO:0048103=IEA, GO:0060122=IEA, GO:0007266=IEA, GO:0009952=IEA, GO:0001947=ISS, GO:0060028=IEA, GO:0016323=IEA, GO:0016324=ISS, GO:0005911=ISS, GO:0032956=IEA, GO:0090103=IEA, GO:0043507=IEA, GO:0022007=IEA, GO:0035019=IEA, GO:0060187=IEA, GO:0001942=IEA, GO:0060490=IEA, GO:0003150=IEA, GO:0003402=IEA, GO:0090179=IEA, GO:0001843=ISS, GO:0045176=ISS, GO:0090177=IEA, GO:0035058=ISS, GO:0016328=ISS, GO:0048546=IEA, GO:0045197=IEA, GO:0060489=IEA, GO:0003149=IEA, GO:0060488=IEA, GO:0042060=IEA, GO:0016021=IEA, GO:0048105=IEA} Rho protein signal transduction, anterior/posterior pattern specification, apical protein localization, cell migration involved in kidney development, cochlea morphogenesis, convergent extension involved in axis elongation, convergent extension involved in neural plate elongation, digestive tract morphogenesis, establishment of body hair planar orientation, establishment of planar polarity, establishment of planar polarity involved in neural tube closure, establishment or maintenance of epithelial cell apical/basal polarity, hair follicle development, heart looping, inner ear receptor stereocilium organization, lateral sprouting involved in lung morphogenesis, membranous septum morphogenesis, muscular septum morphogenesis, neural tube closure, nonmotile primary cilium assembly, orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis, planar cell polarity pathway involved in axis elongation, planar cell polarity pathway involved in neural tube closure, planar dichotomous subdivision of terminal units involved in lung branching morphogenesis, positive regulation of JUN kinase activity, regulation of actin cytoskeleton organization, somatic stem cell division, somatic stem cell maintenance, wound healing apical plasma membrane, basolateral plasma membrane, cell pole, cell-cell junction, integral to membrane, lateral plasma membrane Human UniProtKB:Q91ZD4 VAPA GOC UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0005515=PMID:20029029, GO:0008219=PMID:19289470, GO:0048471=PMID:16895911, GO:0046982=PMID:9920726, GO:0005886=PMID:10523508, GO:0005783=PMID:19289470, GO:0030148=Reactome:REACT_115810, GO:0005874=GO_REF:0000019, GO:0044281=Reactome:REACT_111217, GO:0070972=PMID:19289470, GO:0031982=PMID:10523508, GO:0031175=PMID:19289470, GO:0007165=PMID:12761501, GO:0006944=PMID:9657962, GO:0005198=GO_REF:0000002, GO:0005789=Reactome:REACT_19306, GO:0004871=PMID:12761501, GO:0016021=GO_REF:0000037, GO:0005923=PMID:10523508, GO:0043123=PMID:12761501} Q9P0L0 Vesicle-associated membrane protein-associated protein A protein 20130413 {GO:0006665=TAS, GO:0005515=IPI, GO:0008219=IMP, GO:0048471=IDA, GO:0046982=IPI, GO:0005886=IDA, GO:0005783=IDA, GO:0030148=TAS, GO:0005874=IEA, GO:0044281=TAS, GO:0070972=IMP, GO:0031982=IDA, GO:0031175=IMP, GO:0007165=IMP, GO:0006944=TAS, GO:0005198=IEA, GO:0005789=TAS, GO:0004871=IMP, GO:0016021=IEA, GO:0005923=IDA, GO:0043123=IMP} cell death, cellular membrane fusion, neuron projection development, positive regulation of I-kappaB kinase/NF-kappaB cascade, protein localization to endoplasmic reticulum, signal transduction, small molecule metabolic process, sphingolipid biosynthetic process, sphingolipid metabolic process endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane, microtubule, perinuclear region of cytoplasm, plasma membrane, tight junction, vesicle protein binding, protein heterodimerization activity, signal transducer activity, structural molecule activity Human VAPB IntAct UniProtKB {GO:0006665=Reactome:REACT_19323, GO:0005515=PMID:19289470, GO:0008219=GO_REF:0000037, GO:0005794=PMID:16227268, GO:0046982=PMID:9920726, GO:0005783=PMID:15372378, GO:0030148=Reactome:REACT_115810, GO:0006874=PMID:22131369, GO:0048487=PMID:17540579, GO:0044281=Reactome:REACT_111217, GO:0042803=PMID:9920726, GO:0030968=PMID:16891305, GO:0005198=GO_REF:0000002, GO:0019048=PMID:16227268, GO:0005789=Reactome:REACT_19306, GO:0016021=GO_REF:0000037, GO:0006987=PMID:20940299, GO:0019899=PMID:17540579, GO:0045070=PMID:16227268} O95292 Vesicle-associated membrane protein-associated protein B/C protein 20130415 {GO:0006665=TAS, GO:0005515=IPI, GO:0008219=IEA, GO:0005794=IDA, GO:0046982=IPI, GO:0005783=IDA, GO:0030148=TAS, GO:0006874=IMP, GO:0048487=IDA, GO:0044281=TAS, GO:0042803=IPI, GO:0030968=IMP, GO:0005198=IEA, GO:0019048=IDA, GO:0005789=TAS, GO:0016021=IEA, GO:0006987=IDA, GO:0019899=IPI, GO:0045070=IMP} activation of signaling protein activity involved in unfolded protein response, cell death, cellular calcium ion homeostasis, endoplasmic reticulum unfolded protein response, positive regulation of viral genome replication, small molecule metabolic process, sphingolipid biosynthetic process, sphingolipid metabolic process, virus-host interaction Golgi apparatus, endoplasmic reticulum, endoplasmic reticulum membrane, integral to membrane beta-tubulin binding, enzyme binding, protein binding, protein heterodimerization activity, protein homodimerization activity, structural molecule activity Human UniProtKB:Q5T4F4 VARS ENSEMBL UniProtKB {GO:0005622=GO_REF:0000029, GO:0005739=GO_REF:0000019, GO:0010467=Reactome:REACT_71, GO:0004832=GO_REF:0000019, GO:0005737=GO_REF:0000002, GO:0002161=GO_REF:0000002, GO:0006438=GO_REF:0000002, GO:0005524=GO_REF:0000002, GO:0006418=Reactome:REACT_15482, GO:0005829=Reactome:REACT_15329, GO:0006414=GO_REF:0000029} Q5SP20 Valine--tRNA ligase protein 20130413 {GO:0005622=NAS, GO:0005739=IEA, GO:0010467=TAS, GO:0004832=IEA, GO:0005737=IEA, GO:0002161=IEA, GO:0006438=IEA, GO:0005524=IEA, GO:0006418=TAS, GO:0005829=TAS, GO:0006414=NAS} gene expression, tRNA aminoacylation for protein translation, translational elongation, valyl-tRNA aminoacylation cytoplasm, cytosol, intracellular, mitochondrion ATP binding, aminoacyl-tRNA editing activity, valine-tRNA ligase activity Human Ensembl:ENSMUSP00000084572 VARS2 Reactome UniProtKB {GO:0005739=GO_REF:0000039, GO:0010467=Reactome:REACT_71, GO:0004832=GO_REF:0000003, GO:0002161=GO_REF:0000002, GO:0006438=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0006418=Reactome:REACT_15482} Q5ST30 Valine--tRNA ligase, mitochondrial protein 20130301 {GO:0005739=IEA, GO:0010467=TAS, GO:0004832=IEA, GO:0002161=IEA, GO:0006438=IEA, GO:0005524=IEA, GO:0006418=TAS} gene expression, tRNA aminoacylation for protein translation, valyl-tRNA aminoacylation mitochondrion ATP binding, aminoacyl-tRNA editing activity, valine-tRNA ligase activity Human VASH1 MGI UniProtKB {GO:0005783=PMID:15467828, GO:0009611=PMID:23056314, GO:0045177=PMID:20736312, GO:0001525=PMID:15467828, GO:0005615=PMID:20736312, GO:0010596=PMID:20736312, GO:0005737=PMID:15467828, GO:0001937=PMID:19204325, GO:0016525=PMID:20133819, GO:0007050=GO_REF:0000037, GO:1901491=PMID:20133819, GO:2000772=PMID:23056314, GO:0043537=PMID:15467828} Q7L8A9 Vasohibin-1 protein 20130226 {GO:0005783=IDA, GO:0009611=IDA, GO:0045177=IDA, GO:0001525=IDA, GO:0005615=IDA, GO:0010596=IGI, GO:0005737=IDA, GO:0001937=IDA, GO:0016525=IGI, GO:0007050=IEA, GO:1901491=IGI, GO:2000772=IMP, GO:0043537=IDA} angiogenesis, cell cycle arrest, negative regulation of angiogenesis, negative regulation of blood vessel endothelial cell migration, negative regulation of endothelial cell migration, negative regulation of endothelial cell proliferation, negative regulation of lymphangiogenesis, regulation of cellular senescence, response to wounding apical part of cell, cytoplasm, endoplasmic reticulum, extracellular space Human VASH2 MGI UniProtKB {GO:0005737=PMID:19204325, GO:0001938=PMID:19204325, GO:0045766=PMID:19204325} Q86V25 Vasohibin-2 protein 20090706 {GO:0005737=IDA, GO:0001938=IDA, GO:0045766=IDA} positive regulation of angiogenesis, positive regulation of endothelial cell proliferation cytoplasm Human VASN UniProtKB UniProtKB {GO:0005576=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q6EMK4 Vasorin protein 20130413 {GO:0005576=IEA, GO:0016021=IEA} extracellular region, integral to membrane Human UniProtKB-SubCell:SL-0243 VASP HPA UniProtKB {GO:0005515=PMID:21423205, GO:0050852=Reactome:REACT_12526, GO:0017124=GO_REF:0000037, GO:0005886=GO_REF:0000052, GO:0031258=GO_REF:0000039, GO:0034329=Reactome:REACT_20676, GO:0031527=GO_REF:0000039, GO:0001843=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0015629=PMID:7828592, GO:0005829=Reactome:REACT_20572, GO:0005737=GO_REF:0000052, GO:0051289=GO_REF:0000002, GO:0007411=Reactome:REACT_18266, GO:0008154=GO_REF:0000002, GO:0005925=GO_REF:0000052, GO:0005522=PMID:17914456} P50552 Vasodilator-stimulated phosphoprotein protein 20101115 {GO:0005515=IPI, GO:0050852=TAS, GO:0017124=IEA, GO:0005886=IDA, GO:0031258=IEA, GO:0034329=TAS, GO:0031527=IEA, GO:0001843=IEA, GO:0003779=IEA, GO:0015629=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0051289=IEA, GO:0007411=TAS, GO:0008154=IEA, GO:0005925=IDA, GO:0005522=IPI} T cell receptor signaling pathway, actin polymerization or depolymerization, axon guidance, cell junction assembly, neural tube closure, protein homotetramerization actin cytoskeleton, cytoplasm, cytosol, filopodium membrane, focal adhesion, lamellipodium membrane, plasma membrane SH3 domain binding, actin binding, profilin binding, protein binding Human VAT1 PINC UniProtKB {GO:0010637=PMID:17105775, GO:0016491=GO_REF:0000037, GO:0005741=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0016021=PMID:8938427} Q99536 Synaptic vesicle membrane protein VAT-1 homolog protein 20030904 {GO:0010637=IMP, GO:0016491=IEA, GO:0005741=IEA, GO:0008270=IEA, GO:0016021=TAS} negative regulation of mitochondrial fusion integral to membrane, mitochondrial outer membrane oxidoreductase activity, zinc ion binding Human VAT1L UniProtKB UniProtKB {GO:0016491=GO_REF:0000037, GO:0008270=GO_REF:0000002} Q9HCJ6 Synaptic vesicle membrane protein VAT-1 homolog-like protein 20130413 {GO:0016491=IEA, GO:0008270=IEA} oxidoreductase activity, zinc ion binding Human UniProtKB-KW:KW-0560 VAV1 UniProtKB UniProtKB {GO:0005515=PMID:18692475, GO:0003700=PMID:2477241, GO:0005886=Reactome:REACT_147854, GO:0035023=GO_REF:0000002, GO:0007264=Reactome:REACT_11044, GO:0031295=Reactome:REACT_19344, GO:0046872=GO_REF:0000038, GO:0005829=Reactome:REACT_160260, GO:0035556=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0005085=Reactome:REACT_111195, GO:0005543=GO_REF:0000002, GO:0007173=Reactome:REACT_9417, GO:0005089=GO_REF:0000002, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0006355=PMID:2477241, GO:0048015=Reactome:REACT_12464, GO:0006915=Reactome:REACT_13638, GO:0030168=Reactome:REACT_798, GO:0097190=Reactome:REACT_13720, GO:0007596=Reactome:REACT_604, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0038096=Reactome:REACT_160123} Q96D37 Proto-oncogene vav protein 20130413 {GO:0005515=IPI, GO:0003700=TAS, GO:0005886=TAS, GO:0035023=IEA, GO:0007264=TAS, GO:0031295=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0035556=IEA, GO:0005622=IEA, GO:0005085=TAS, GO:0005543=IEA, GO:0007173=TAS, GO:0005089=IEA, GO:0051056=TAS, GO:0048011=TAS, GO:0006355=TAS, GO:0048015=TAS, GO:0006915=TAS, GO:0030168=TAS, GO:0097190=TAS, GO:0007596=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0038096=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, T cell costimulation, apoptotic process, apoptotic signaling pathway, blood coagulation, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, innate immune response, intracellular signal transduction, neurotrophin TRK receptor signaling pathway, phosphatidylinositol-mediated signaling, platelet activation, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, regulation of transcription, DNA-dependent, small GTPase mediated signal transduction cytosol, intracellular, plasma membrane Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, metal ion binding, phospholipid binding, protein binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-KW:KW-0479 VAV2 IntAct UniProtKB {GO:0005515=PMID:18654987, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0005154=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0007264=Reactome:REACT_11044, GO:0035023=GO_REF:0000002, GO:0030032=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0006915=Reactome:REACT_13638, GO:0001525=GO_REF:0000037, GO:0097190=Reactome:REACT_13720, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_160260, GO:0005085=Reactome:REACT_147838, GO:0007165=PMID:7762982, GO:0005543=GO_REF:0000002, GO:0016477=GO_REF:0000019, GO:0043552=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0007411=Reactome:REACT_18266, GO:0045087=Reactome:REACT_6802, GO:0005089=GO_REF:0000002, GO:0038096=Reactome:REACT_160123} P52735 Guanine nucleotide exchange factor VAV2 protein 20130415 {GO:0005515=IPI, GO:0051056=TAS, GO:0048011=TAS, GO:0005154=IEA, GO:0005886=IEA, GO:0007264=TAS, GO:0035023=IEA, GO:0030032=IEA, GO:0030168=TAS, GO:0006915=TAS, GO:0001525=IEA, GO:0097190=TAS, GO:0046872=IEA, GO:0005829=TAS, GO:0005085=TAS, GO:0007165=TAS, GO:0005543=IEA, GO:0016477=IEA, GO:0043552=IEA, GO:0007596=TAS, GO:0007411=TAS, GO:0045087=TAS, GO:0005089=IEA, GO:0038096=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, angiogenesis, apoptotic process, apoptotic signaling pathway, axon guidance, blood coagulation, cell migration, innate immune response, lamellipodium assembly, neurotrophin TRK receptor signaling pathway, platelet activation, positive regulation of phosphatidylinositol 3-kinase activity, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, signal transduction, small GTPase mediated signal transduction cytosol, plasma membrane Rho guanyl-nucleotide exchange factor activity, epidermal growth factor receptor binding, guanyl-nucleotide exchange factor activity, metal ion binding, phospholipid binding, protein binding Human UniProtKB:O75674 VAV3 GOC UniProtKB {GO:0005515=PMID:21706016, GO:0050853=PMID:17875758, GO:0005154=GO_REF:0000019, GO:0005886=GO_REF:0000019, GO:0007264=Reactome:REACT_11044, GO:0035023=GO_REF:0000002, GO:0030890=PMID:17875758, GO:0030032=GO_REF:0000019, GO:0006906=GO_REF:0000019, GO:0046872=GO_REF:0000037, GO:0005829=Reactome:REACT_160260, GO:0005085=Reactome:REACT_147838, GO:0035556=GO_REF:0000002, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000019, GO:0005543=GO_REF:0000002, GO:0043552=GO_REF:0000019, GO:0005089=GO_REF:0000002, GO:0030676=GO_REF:0000019, GO:0051056=Reactome:REACT_11051, GO:0048011=Reactome:REACT_13776, GO:0042493=PMID:17875758, GO:0030168=Reactome:REACT_798, GO:0006915=Reactome:REACT_13638, GO:0001525=GO_REF:0000037, GO:0097190=Reactome:REACT_13720, GO:0043087=GO_REF:0000019, GO:0006974=PMID:17875758, GO:0045785=GO_REF:0000019, GO:0043547=PMID:10523675, GO:0016477=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0007229=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0005070=PMID:10523675, GO:0038096=Reactome:REACT_160123, GO:0005096=PMID:10523675} Q9UKW4 Guanine nucleotide exchange factor VAV3 protein 20130413 {GO:0005515=IPI, GO:0050853=IMP, GO:0005154=IEA, GO:0005886=IEA, GO:0007264=TAS, GO:0035023=IEA, GO:0030890=IMP, GO:0030032=IEA, GO:0006906=IEA, GO:0046872=IEA, GO:0005829=TAS, GO:0005085=TAS, GO:0035556=IEA, GO:0005622=IEA, GO:0005737=IEA, GO:0005543=IEA, GO:0043552=IEA, GO:0005089=IEA, GO:0030676=IEA, GO:0051056=TAS, GO:0048011=TAS, GO:0042493=IMP, GO:0030168=TAS, GO:0006915=TAS, GO:0001525=IEA, GO:0097190=TAS, GO:0043087=IEA, GO:0006974=IMP, GO:0045785=IEA, GO:0043547=TAS, GO:0016477=IEA, GO:0007596=TAS, GO:0007229=IEA, GO:0045087=TAS, GO:0005070=TAS, GO:0038096=TAS, GO:0005096=TAS} B cell receptor signaling pathway, Fc-gamma receptor signaling pathway involved in phagocytosis, angiogenesis, apoptotic process, apoptotic signaling pathway, blood coagulation, cell migration, innate immune response, integrin-mediated signaling pathway, intracellular signal transduction, lamellipodium assembly, neurotrophin TRK receptor signaling pathway, platelet activation, positive regulation of B cell proliferation, positive regulation of GTPase activity, positive regulation of cell adhesion, positive regulation of phosphatidylinositol 3-kinase activity, regulation of GTPase activity, regulation of Rho protein signal transduction, regulation of small GTPase mediated signal transduction, response to DNA damage stimulus, response to drug, small GTPase mediated signal transduction, vesicle fusion cytoplasm, cytosol, intracellular, plasma membrane GTPase activator activity, Rac guanyl-nucleotide exchange factor activity, Rho guanyl-nucleotide exchange factor activity, SH3/SH2 adaptor activity, epidermal growth factor receptor binding, guanyl-nucleotide exchange factor activity, metal ion binding, phospholipid binding, protein binding Human VBP1 HPA UniProtKB {GO:0005515=PMID:22190034, GO:0005737=GO_REF:0000052, GO:0006457=Reactome:REACT_17004, GO:0016272=GO_REF:0000002, GO:0051084=Reactome:REACT_16952, GO:0005634=GO_REF:0000039, GO:0051082=GO_REF:0000002, GO:0044267=Reactome:REACT_17015, GO:0043231=GO_REF:0000052} P61758 Prefoldin subunit 3 protein 20101115 {GO:0005515=IPI, GO:0005737=IDA, GO:0006457=TAS, GO:0016272=IEA, GO:0051084=TAS, GO:0005634=IEA, GO:0051082=IEA, GO:0044267=TAS, GO:0043231=IDA} 'de novo' posttranslational protein folding, cellular protein metabolic process, protein folding cytoplasm, intracellular membrane-bounded organelle, nucleus, prefoldin complex protein binding, unfolded protein binding Human VCAM1 BHF-UCL UniProtKB {GO:0060710=GO_REF:0000019, GO:0005886=Reactome:REACT_25082, GO:0019221=Reactome:REACT_25229, GO:0002102=PMID:15220135, GO:0030175=PMID:12082081, GO:0005615=PMID:9290466, GO:0050901=PMID:2688898, GO:0007507=GO_REF:0000019, GO:0016337=GO_REF:0000002, GO:0010212=GO_REF:0000019, GO:0030183=PMID:1715889, GO:0042102=PMID:1381355, GO:0007159=PMID:1715889, GO:0022614=PMID:12082081, GO:0071333=GO_REF:0000019, GO:0007155=PMID:16809613, GO:0050839=PMID:12082081, GO:0007157=PMID:1715889, GO:0060333=Reactome:REACT_25078, GO:0001666=GO_REF:0000019, GO:0002526=GO_REF:0000019, GO:0009986=PMID:1715889, GO:0007584=GO_REF:0000019, GO:0007568=GO_REF:0000019, GO:0045177=PMID:12082081, GO:0002544=GO_REF:0000019, GO:0042383=GO_REF:0000019, GO:0005902=PMID:12082081, GO:0005178=PMID:15220135, GO:0071065=PMID:15220135, GO:0019048=GO_REF:0000037, GO:0050776=Reactome:REACT_11152, GO:0016021=GO_REF:0000037, GO:0009897=PMID:1377228} P19320 Vascular cell adhesion protein 1 protein 20110220 {GO:0060710=IEA, GO:0005886=TAS, GO:0019221=TAS, GO:0002102=IDA, GO:0030175=IDA, GO:0005615=IDA, GO:0050901=IEP, GO:0007507=IEA, GO:0016337=IEA, GO:0010212=IEA, GO:0030183=IC, GO:0042102=IDA, GO:0007159=IDA, GO:0022614=IEP, GO:0071333=IEA, GO:0007155=IDA, GO:0050839=IPI, GO:0007157=IDA, GO:0060333=TAS, GO:0001666=IEA, GO:0002526=IEA, GO:0009986=IDA, GO:0007584=IEA, GO:0007568=IEA, GO:0045177=IDA, GO:0002544=IEA, GO:0042383=IEA, GO:0005902=IDA, GO:0005178=IDA, GO:0071065=IDA, GO:0019048=IEA, GO:0050776=TAS, GO:0016021=IEA, GO:0009897=IDA} B cell differentiation, acute inflammatory response, aging, cell adhesion, cell-cell adhesion, cellular response to glucose stimulus, chorio-allantoic fusion, chronic inflammatory response, cytokine-mediated signaling pathway, heart development, heterophilic cell-cell adhesion, interferon-gamma-mediated signaling pathway, leukocyte cell-cell adhesion, leukocyte tethering or rolling, membrane to membrane docking, positive regulation of T cell proliferation, regulation of immune response, response to hypoxia, response to ionizing radiation, response to nutrient, virus-host interaction alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex, apical part of cell, cell surface, external side of plasma membrane, extracellular space, filopodium, integral to membrane, microvillus, plasma membrane, podosome, sarcolemma cell adhesion molecule binding, integrin binding Human VCAN InterPro UniProtKB {GO:0008037=PMID:2583089, GO:0005796=Reactome:REACT_120955, GO:0005975=Reactome:REACT_474, GO:0005509=GO_REF:0000002, GO:0005578=GO_REF:0000039, GO:0005576=Reactome:REACT_121341, GO:0007275=PMID:2583089, GO:0044281=Reactome:REACT_111217, GO:0005539=PMID:7528742, GO:0031012=PMID:22261194, GO:0030208=Reactome:REACT_120800, GO:0007507=GO_REF:0000019, GO:0030207=Reactome:REACT_120888, GO:0030206=Reactome:REACT_120989, GO:0005540=GO_REF:0000002, GO:0030246=GO_REF:0000002, GO:0007155=GO_REF:0000002, GO:0030204=Reactome:REACT_121206, GO:0030203=Reactome:REACT_121408, GO:0043202=Reactome:REACT_121272} Q86W61 VCAN protein protein 20130413 {GO:0008037=TAS, GO:0005796=TAS, GO:0005975=TAS, GO:0005509=IEA, GO:0005578=IEA, GO:0005576=TAS, GO:0007275=TAS, GO:0044281=TAS, GO:0005539=TAS, GO:0031012=ISS, GO:0030208=TAS, GO:0007507=IEA, GO:0030207=TAS, GO:0030206=TAS, GO:0005540=IEA, GO:0030246=IEA, GO:0007155=IEA, GO:0030204=TAS, GO:0030203=TAS, GO:0043202=TAS} carbohydrate metabolic process, cell adhesion, cell recognition, chondroitin sulfate biosynthetic process, chondroitin sulfate catabolic process, chondroitin sulfate metabolic process, dermatan sulfate biosynthetic process, glycosaminoglycan metabolic process, heart development, multicellular organismal development, small molecule metabolic process Golgi lumen, extracellular matrix, extracellular region, lysosomal lumen, proteinaceous extracellular matrix calcium ion binding, carbohydrate binding, glycosaminoglycan binding, hyaluronic acid binding Human InterPro:IPR000538 VCL ENSEMBL UniProtKB {GO:0005515=PMID:10320934, GO:0030055=PMID:2116004, GO:0030018=GO_REF:0000019, GO:0002162=PMID:18341635, GO:0008013=PMID:20086044, GO:0034333=PMID:20086044, GO:0030032=GO_REF:0000019, GO:0006928=PMID:16130169, GO:0015629=GO_REF:0000002, GO:0005829=Reactome:REACT_21347, GO:0043297=PMID:9700171, GO:0005916=GO_REF:0000019, GO:0005913=PMID:20086044, GO:0006936=Reactome:REACT_20558, GO:0005912=GO_REF:0000024, GO:0005911=GO_REF:0000024, GO:0005856=PMID:16130169, GO:0007155=GO_REF:0000019, GO:0030334=GO_REF:0000019, GO:0090136=PMID:20086044, GO:0030336=PMID:15494027, GO:0045296=PMID:20086044, GO:0045294=PMID:9700171, GO:0030168=Reactome:REACT_798, GO:0003779=PMID:7816144, GO:0005576=Reactome:REACT_21347, GO:0042383=GO_REF:0000019, GO:0043234=PMID:9700171, GO:0007160=PMID:20086044, GO:0007596=Reactome:REACT_604, GO:0005198=GO_REF:0000002, GO:0034394=PMID:20086044, GO:0002576=Reactome:REACT_318, GO:0043034=GO_REF:0000019, GO:0017048=GO_REF:0000019, GO:0002009=PMID:20086044, GO:0005925=GO_REF:0000019} Q5JQ13 Vinculin protein 20130413 {GO:0005515=IPI, GO:0030055=NAS, GO:0030018=IEA, GO:0002162=IPI, GO:0008013=ISS, GO:0034333=IMP, GO:0030032=IEA, GO:0006928=TAS, GO:0015629=IEA, GO:0005829=TAS, GO:0043297=IMP, GO:0005916=IEA, GO:0005913=IDA, GO:0006936=TAS, GO:0005912=ISS, GO:0005911=ISS, GO:0005856=TAS, GO:0007155=IEA, GO:0030334=IEA, GO:0090136=IMP, GO:0030336=TAS, GO:0045296=ISS, GO:0045294=IPI, GO:0030168=TAS, GO:0003779=IDA, GO:0005576=TAS, GO:0042383=IEA, GO:0043234=IDA, GO:0007160=TAS, GO:0007596=TAS, GO:0005198=IEA, GO:0034394=IMP, GO:0002576=TAS, GO:0043034=IEA, GO:0017048=IEA, GO:0002009=IMP, GO:0005925=IEA} adherens junction assembly, apical junction assembly, blood coagulation, cell adhesion, cell-matrix adhesion, cellular component movement, epithelial cell-cell adhesion, lamellipodium assembly, morphogenesis of an epithelium, muscle contraction, negative regulation of cell migration, platelet activation, platelet degranulation, protein localization to cell surface, regulation of cell migration Z disc, actin cytoskeleton, adherens junction, cell-cell adherens junction, cell-cell junction, cell-substrate junction, costamere, cytoskeleton, cytosol, extracellular region, fascia adherens, focal adhesion, protein complex, sarcolemma Rho GTPase binding, actin binding, alpha-catenin binding, beta-catenin binding, cadherin binding, dystroglycan binding, protein binding, structural molecule activity Human Ensembl:ENSMUSP00000022369 VCP BHF-UCL UniProtKB {GO:0005515=PMID:18775313, GO:0006511=GO_REF:0000019, GO:0045732=PMID:11483959, GO:0016567=PMID:22120668, GO:0005783=PMID:15215856, GO:0032436=PMID:9452483, GO:0005634=GO_REF:0000052, GO:0019985=PMID:23042605, GO:0032403=GO_REF:0000019, GO:0045184=PMID:15215856, GO:0030968=PMID:15215856, GO:0008289=GO_REF:0000037, GO:0043231=GO_REF:0000024, GO:0005829=PMID:15215856, GO:0006302=PMID:22120668, GO:0042802=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0031334=PMID:18775313, GO:0051260=GO_REF:0000019, GO:0016887=PMID:15215856, GO:0018279=PMID:22607976, GO:0000502=PMID:9452483, GO:0006919=GO_REF:0000024, GO:0019903=PMID:10364224, GO:0030970=PMID:15215856, GO:0019904=PMID:15362974, GO:0035861=PMID:22120668, GO:0005102=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0042981=PMID:16130169, GO:0030433=PMID:22607976, GO:0005524=GO_REF:0000019, GO:0006974=PMID:22120668, GO:0006888=GO_REF:0000019, GO:0043234=GO_REF:0000019, GO:0006281=PMID:16140914, GO:0070842=GO_REF:0000019, GO:0043161=PMID:15743842, GO:0031593=PMID:11483959} P55072 Transitional endoplasmic reticulum ATPase protein 20100120 {GO:0005515=IPI, GO:0006511=IEA, GO:0045732=IDA, GO:0016567=IDA, GO:0005783=IDA, GO:0032436=IDA, GO:0005634=IDA, GO:0019985=IMP, GO:0032403=IEA, GO:0045184=TAS, GO:0030968=TAS, GO:0008289=IEA, GO:0043231=ISS, GO:0005829=IDA, GO:0006302=IDA, GO:0042802=IEA, GO:0005737=IDA, GO:0031334=IDA, GO:0051260=IEA, GO:0016887=TAS, GO:0018279=IMP, GO:0000502=IDA, GO:0006919=ISS, GO:0019903=IPI, GO:0030970=IDA, GO:0019904=IPI, GO:0035861=IDA, GO:0005102=IEA, GO:0005730=IDA, GO:0042981=TAS, GO:0030433=IMP, GO:0005524=IEA, GO:0006974=IDA, GO:0006888=IEA, GO:0043234=IEA, GO:0006281=NAS, GO:0070842=IEA, GO:0043161=NAS, GO:0031593=IDA} DNA repair, ER to Golgi vesicle-mediated transport, ER-associated protein catabolic process, activation of cysteine-type endopeptidase activity involved in apoptotic process, aggresome assembly, double-strand break repair, endoplasmic reticulum unfolded protein response, establishment of protein localization, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of protein catabolic process, positive regulation of protein complex assembly, proteasomal ubiquitin-dependent protein catabolic process, protein N-linked glycosylation via asparagine, protein homooligomerization, protein ubiquitination, regulation of apoptotic process, response to DNA damage stimulus, retrograde protein transport, ER to cytosol, translesion synthesis, ubiquitin-dependent protein catabolic process cytoplasm, cytosol, endoplasmic reticulum, intracellular membrane-bounded organelle, nucleolus, nucleus, proteasome complex, protein complex, site of double-strand break ATP binding, ATPase activity, identical protein binding, lipid binding, polyubiquitin binding, protein binding, protein complex binding, protein domain specific binding, protein phosphatase binding, receptor binding Human VCPIP1 LIFEdb UniProtKB {GO:0005737=GO_REF:0000054, GO:0007067=GO_REF:0000019, GO:0016567=GO_REF:0000024, GO:0004843=GO_REF:0000024, GO:0005795=GO_REF:0000039, GO:0005783=GO_REF:0000039, GO:0016320=GO_REF:0000019, GO:0006508=GO_REF:0000037, GO:0090168=GO_REF:0000019} Q96JH7 Deubiquitinating protein VCIP135 protein 20100607 {GO:0005737=IDA, GO:0007067=IEA, GO:0016567=ISS, GO:0004843=ISS, GO:0005795=IEA, GO:0005783=IEA, GO:0016320=IEA, GO:0006508=IEA, GO:0090168=IEA} Golgi reassembly, endoplasmic reticulum membrane fusion, mitosis, protein ubiquitination, proteolysis Golgi stack, cytoplasm, endoplasmic reticulum ubiquitin-specific protease activity Human VCY1B null null {} null null null null {} null null null VDAC1 BHF-UCL UniProtKB {GO:0042645=PMID:18063578, GO:0006820=PMID:8420959, GO:0005515=PMID:22304920, GO:0005886=GO_REF:0000039, GO:0005743=GO_REF:0000019, GO:0006915=PMID:10365962, GO:0005741=GO_REF:0000039, GO:0007270=GO_REF:0000019, GO:0005739=PMID:8420959, GO:0046930=PMID:9843949, GO:0016020=GO_REF:0000024, GO:0019048=GO_REF:0000037, GO:0001662=GO_REF:0000019, GO:0015288=GO_REF:0000037, GO:0007612=GO_REF:0000019, GO:0008308=GO_REF:0000024} P21796 Voltage-dependent anion-selective channel protein 1 protein 20090218 {GO:0042645=IDA, GO:0006820=TAS, GO:0005515=IPI, GO:0005886=IEA, GO:0005743=IEA, GO:0006915=TAS, GO:0005741=IEA, GO:0007270=IEA, GO:0005739=TAS, GO:0046930=TAS, GO:0016020=ISS, GO:0019048=IEA, GO:0001662=IEA, GO:0015288=IEA, GO:0007612=IEA, GO:0008308=ISS} anion transport, apoptotic process, behavioral fear response, learning, neuron-neuron synaptic transmission, virus-host interaction membrane, mitochondrial inner membrane, mitochondrial nucleoid, mitochondrial outer membrane, mitochondrion, plasma membrane, pore complex porin activity, protein binding, voltage-gated anion channel activity Human VDAC2 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0042645=PMID:18063578, GO:0005515=PMID:15082785, GO:0006820=PMID:8420959, GO:0046930=GO_REF:0000037, GO:0000166=GO_REF:0000037, GO:0032272=GO_REF:0000019, GO:0005743=GO_REF:0000019, GO:0015288=GO_REF:0000037, GO:0005741=GO_REF:0000002, GO:2001243=GO_REF:0000019, GO:0008308=GO_REF:0000002} Q5JSD2 Voltage-dependent anion-selective channel protein 2 protein 20110516 {GO:0005739=IDA, GO:0042645=IDA, GO:0005515=IPI, GO:0006820=TAS, GO:0046930=IEA, GO:0000166=IEA, GO:0032272=IEA, GO:0005743=IEA, GO:0015288=IEA, GO:0005741=IEA, GO:2001243=IEA, GO:0008308=IEA} anion transport, negative regulation of intrinsic apoptotic signaling pathway, negative regulation of protein polymerization mitochondrial inner membrane, mitochondrial nucleoid, mitochondrial outer membrane, mitochondrion, pore complex nucleotide binding, porin activity, protein binding, voltage-gated anion channel activity Human VDAC3 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0046930=GO_REF:0000037, GO:0000166=GO_REF:0000037, GO:0015288=GO_REF:0000037, GO:0005741=GO_REF:0000039, GO:0015853=PMID:9781040, GO:0008308=PMID:9781040, GO:0055085=GO_REF:0000002} Q9Y277 Voltage-dependent anion-selective channel protein 3 protein 20101115 {GO:0005739=IDA, GO:0046930=IEA, GO:0000166=IEA, GO:0015288=IEA, GO:0005741=IEA, GO:0015853=TAS, GO:0008308=TAS, GO:0055085=IEA} adenine transport, transmembrane transport mitochondrial outer membrane, mitochondrion, pore complex nucleotide binding, porin activity, voltage-gated anion channel activity Human VDR BHF-UCL UniProtKB {GO:0060558=GO_REF:0000024, GO:0005515=PMID:17426122, GO:0010839=PMID:17223341, GO:0010467=Reactome:REACT_71, GO:0008285=PMID:16549446, GO:0003700=PMID:17426122, GO:0006367=Reactome:REACT_15525, GO:0003707=GO_REF:0000002, GO:0005634=PMID:15589699, GO:0046697=PMID:16720713, GO:0046965=PMID:17426122, GO:0010980=PMID:16549446, GO:0045618=PMID:17082781, GO:0009887=GO_REF:0000019, GO:0006816=GO_REF:0000019, GO:0004879=GO_REF:0000019, GO:0008434=PMID:16549446, GO:0060745=GO_REF:0000019, GO:0060058=GO_REF:0000019, GO:0006874=GO_REF:0000019, GO:0000122=PMID:17426122, GO:0003677=PMID:11891224, GO:0043565=GO_REF:0000002, GO:0007165=PMID:2849209, GO:0050892=GO_REF:0000019, GO:0001501=GO_REF:0000019, GO:0070561=PMID:16549446, GO:0007595=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_19207, GO:0070644=PMID:17426122, GO:0045892=PMID:11891224} P11473 Vitamin D3 receptor protein 20090624 {GO:0060558=ISS, GO:0005515=IPI, GO:0010839=IMP, GO:0010467=TAS, GO:0008285=IDA, GO:0003700=IDA, GO:0006367=TAS, GO:0003707=IEA, GO:0005634=IDA, GO:0046697=IEP, GO:0046965=IPI, GO:0010980=IDA, GO:0045618=IMP, GO:0009887=IEA, GO:0006816=IEA, GO:0004879=IEA, GO:0008434=IDA, GO:0060745=IEA, GO:0060058=IEA, GO:0006874=IEA, GO:0000122=IDA, GO:0003677=IDA, GO:0043565=IEA, GO:0007165=TAS, GO:0050892=IEA, GO:0001501=IEA, GO:0070561=IDA, GO:0007595=IEA, GO:0008270=IEA, GO:0005654=TAS, GO:0070644=IDA, GO:0045892=IDA} calcium ion transport, cellular calcium ion homeostasis, decidualization, gene expression, intestinal absorption, lactation, mammary gland branching involved in pregnancy, negative regulation of cell proliferation, negative regulation of keratinocyte proliferation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, organ morphogenesis, positive regulation of apoptotic process involved in mammary gland involution, positive regulation of keratinocyte differentiation, positive regulation of vitamin D 24-hydroxylase activity, regulation of calcidiol 1-monooxygenase activity, signal transduction, skeletal system development, transcription initiation from RNA polymerase II promoter, vitamin D receptor signaling pathway nucleoplasm, nucleus DNA binding, ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, protein binding, retinoid X receptor binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, steroid hormone receptor activity, vitamin D response element binding, vitamin D3 receptor activity, zinc ion binding Human VEGFA BHF-UCL UniProtKB {GO:0005515=PMID:10543948, GO:0050731=PMID:10022831, GO:0048844=GO_REF:0000024, GO:0048593=GO_REF:0000024, GO:0005615=PMID:9202027, GO:1900745=PMID:18386220, GO:1901492=GO_REF:0000019, GO:0048255=GO_REF:0000019, GO:0048018=PMID:20660291, GO:0046982=PMID:8702615, GO:0009986=PMID:17470632, GO:0050840=PMID:14570917, GO:0030168=Reactome:REACT_798, GO:0001701=GO_REF:0000024, GO:0042056=PMID:17082651, GO:0005125=GO_REF:0000024, GO:0031077=GO_REF:0000024, GO:0005604=GO_REF:0000019, GO:0050930=PMID:12744932, GO:0010595=PMID:21245381, GO:0043184=PMID:20660291, GO:0040007=GO_REF:0000024, GO:0042462=GO_REF:0000024, GO:0005172=PMID:10471394, GO:0043183=PMID:1312256, GO:0042088=GO_REF:0000019, GO:0050927=PMID:12744932, GO:0060319=GO_REF:0000024, GO:0030225=PMID:21149635, GO:0048469=GO_REF:0000024, GO:0030224=PMID:21149635, GO:0043154=PMID:18386220, GO:0001968=PMID:14570917, GO:0048010=Reactome:REACT_12529, GO:0001569=GO_REF:0000024, GO:0001822=GO_REF:0000024, GO:0005578=PMID:14570917, GO:0071456=Reactome:REACT_121311, GO:0005576=Reactome:REACT_121365, GO:0048661=GO_REF:0000019, GO:0007399=PMID:15351965, GO:0016020=GO_REF:0000002, GO:0007595=GO_REF:0000024, GO:0060948=GO_REF:0000024, GO:0001974=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0002687=PMID:1312256, GO:0007498=GO_REF:0000024, GO:0048754=GO_REF:0000024, GO:0001570=PMID:15015550, GO:0060749=GO_REF:0000024, GO:0043498=PMID:17470632, GO:0008360=PMID:10527820, GO:0009409=GO_REF:0000019, GO:0042803=GO_REF:0000024, GO:0007610=GO_REF:0000019, GO:0043129=GO_REF:0000024, GO:0051781=GO_REF:0000037, GO:1901727=PMID:20497126, GO:0050679=GO_REF:0000024, GO:0030335=PMID:17470632, GO:0048286=GO_REF:0000019, GO:0033554=Reactome:REACT_120956, GO:0005161=PMID:17470632, GO:0045785=PMID:19674970, GO:0048739=GO_REF:0000024, GO:0043536=PMID:9202027, GO:0008083=PMID:9202027, GO:0030949=PMID:7929439, GO:0008284=PMID:7929439, GO:0030324=GO_REF:0000024, GO:0008283=GO_REF:0000019, GO:0002042=PMID:20660291, GO:0061418=Reactome:REACT_120815, GO:0003169=GO_REF:0000024, GO:0051894=PMID:16489009, GO:0045779=GO_REF:0000019, GO:0001541=GO_REF:0000024, GO:0005737=GO_REF:0000019, GO:0031334=PMID:16489009, GO:0045944=PMID:18093989, GO:0030855=GO_REF:0000024, GO:0031093=Reactome:REACT_21351, GO:0008201=PMID:14570917, GO:0090190=GO_REF:0000024, GO:0001666=PMID:16490744, GO:0043066=PMID:10066377, GO:0035148=PMID:19033661, GO:0031988=GO_REF:0000019, GO:0002052=GO_REF:0000024, GO:0002053=GO_REF:0000024, GO:0009967=GO_REF:0000019, GO:0001525=PMID:11427521, GO:0045766=PMID:18577655, GO:0003151=GO_REF:0000024, GO:0036303=GO_REF:0000024, GO:0003007=GO_REF:0000024, GO:0016477=GO_REF:0000019, GO:0001938=PMID:10022831, GO:0071542=GO_REF:0000024, GO:0060982=GO_REF:0000024, GO:0001934=PMID:19033661, GO:0043117=GO_REF:0000019, GO:0051272=PMID:10527820} P15692 Vascular endothelial growth factor A protein 20120920 {GO:0005515=IPI, GO:0050731=IDA, GO:0048844=ISS, GO:0048593=ISS, GO:0005615=IDA, GO:1900745=IDA, GO:1901492=IEA, GO:0048255=IEA, GO:0048018=IPI, GO:0046982=IDA, GO:0009986=IDA, GO:0050840=IC, GO:0030168=TAS, GO:0001701=ISS, GO:0042056=IDA, GO:0005125=ISS, GO:0031077=ISS, GO:0005604=IEA, GO:0050930=NAS, GO:0010595=IDA, GO:0043184=IPI, GO:0040007=ISS, GO:0042462=ISS, GO:0005172=IPI, GO:0043183=IPI, GO:0042088=IEA, GO:0050927=IDA, GO:0060319=ISS, GO:0030225=IDA, GO:0048469=ISS, GO:0030224=IDA, GO:0043154=IDA, GO:0001968=IDA, GO:0048010=TAS, GO:0001569=ISS, GO:0001822=ISS, GO:0005578=NAS, GO:0071456=TAS, GO:0005576=TAS, GO:0048661=IEA, GO:0007399=TAS, GO:0016020=IEA, GO:0007595=ISS, GO:0060948=ISS, GO:0001974=IEA, GO:0007596=TAS, GO:0002576=TAS, GO:0002687=TAS, GO:0007498=ISS, GO:0048754=ISS, GO:0001570=TAS, GO:0060749=ISS, GO:0043498=IDA, GO:0008360=IDA, GO:0009409=IEA, GO:0042803=ISS, GO:0007610=IEA, GO:0043129=ISS, GO:0051781=IEA, GO:1901727=IDA, GO:0050679=ISS, GO:0030335=IDA, GO:0048286=IEA, GO:0033554=TAS, GO:0005161=IPI, GO:0045785=IDA, GO:0048739=ISS, GO:0043536=IDA, GO:0008083=IDA, GO:0030949=IDA, GO:0008284=IDA, GO:0030324=ISS, GO:0008283=IEA, GO:0002042=IDA, GO:0061418=TAS, GO:0003169=ISS, GO:0051894=IDA, GO:0045779=IEA, GO:0001541=ISS, GO:0005737=IEA, GO:0031334=IDA, GO:0045944=IMP, GO:0030855=ISS, GO:0031093=TAS, GO:0008201=IMP, GO:0090190=ISS, GO:0001666=IDA, GO:0043066=IMP, GO:0035148=IDA, GO:0031988=IEA, GO:0002052=ISS, GO:0002053=ISS, GO:0009967=IEA, GO:0001525=IDA, GO:0045766=IDA, GO:0003151=ISS, GO:0036303=ISS, GO:0003007=ISS, GO:0016477=IEA, GO:0001938=IDA, GO:0071542=ISS, GO:0060982=ISS, GO:0001934=IDA, GO:0043117=IEA, GO:0051272=IDA} T-helper 1 type immune response, angiogenesis, artery morphogenesis, behavior, blood coagulation, blood vessel remodeling, branching morphogenesis of an epithelial tube, camera-type eye morphogenesis, cardiac muscle fiber development, cardiac vascular smooth muscle cell development, cell maturation, cell migration, cell migration involved in sprouting angiogenesis, cell proliferation, cellular response to hypoxia, cellular response to stress, coronary artery morphogenesis, coronary vein morphogenesis, dopaminergic neuron differentiation, epithelial cell differentiation, eye photoreceptor cell development, growth, heart morphogenesis, in utero embryonic development, induction of positive chemotaxis, kidney development, lactation, lung alveolus development, lung development, lymph vessel morphogenesis, mRNA stabilization, macrophage differentiation, mammary gland alveolus development, mesoderm development, monocyte differentiation, negative regulation of apoptotic process, negative regulation of bone resorption, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, nervous system development, outflow tract morphogenesis, ovarian follicle development, patterning of blood vessels, platelet activation, platelet degranulation, positive regulation of angiogenesis, positive regulation of blood vessel endothelial cell migration, positive regulation of branching involved in ureteric bud morphogenesis, positive regulation of cell adhesion, positive regulation of cell division, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of cellular component movement, positive regulation of endothelial cell migration, positive regulation of endothelial cell proliferation, positive regulation of epithelial cell proliferation, positive regulation of focal adhesion assembly, positive regulation of histone deacetylase activity, positive regulation of leukocyte migration, positive regulation of lymphangiogenesis, positive regulation of mesenchymal cell proliferation, positive regulation of neuroblast proliferation, positive regulation of p38MAPK cascade, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of positive chemotaxis, positive regulation of protein complex assembly, positive regulation of protein phosphorylation, positive regulation of signal transduction, positive regulation of smooth muscle cell proliferation, positive regulation of transcription from RNA polymerase II promoter, positive regulation of vascular endothelial growth factor receptor signaling pathway, positive regulation of vascular permeability, post-embryonic camera-type eye development, primitive erythrocyte differentiation, regulation of cell shape, regulation of transcription from RNA polymerase II promoter in response to hypoxia, response to cold, response to hypoxia, surfactant homeostasis, tube formation, vascular endothelial growth factor receptor signaling pathway, vasculogenesis basement membrane, cell surface, cytoplasm, extracellular region, extracellular space, membrane, membrane-bounded vesicle, platelet alpha granule lumen, proteinaceous extracellular matrix cell surface binding, chemoattractant activity, cytokine activity, extracellular matrix binding, fibronectin binding, growth factor activity, heparin binding, platelet-derived growth factor receptor binding, protein binding, protein heterodimerization activity, protein homodimerization activity, receptor agonist activity, vascular endothelial growth factor receptor 1 binding, vascular endothelial growth factor receptor 2 binding, vascular endothelial growth factor receptor binding Human UniProtKB:Q00731 VEGFB Reactome UniProtKB {GO:0005515=PMID:19483306, GO:0048010=Reactome:REACT_12529, GO:0046982=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_21351, GO:0001525=GO_REF:0000019, GO:0060048=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0060976=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0006493=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0031093=Reactome:REACT_21351, GO:0051781=GO_REF:0000037, GO:0008083=GO_REF:0000037, GO:0008201=GO_REF:0000037} P49765 Vascular endothelial growth factor B protein 20130109 {GO:0005515=IPI, GO:0048010=TAS, GO:0046982=IEA, GO:0042493=IEA, GO:0030168=TAS, GO:0005576=TAS, GO:0001525=IEA, GO:0060048=IEA, GO:0042803=IEA, GO:0060976=IEA, GO:0016020=IEA, GO:0006493=IEA, GO:0007596=TAS, GO:0002576=TAS, GO:0031093=TAS, GO:0051781=IEA, GO:0008083=IEA, GO:0008201=IEA} angiogenesis, blood coagulation, cardiac muscle contraction, coronary vasculature development, platelet activation, platelet degranulation, positive regulation of cell division, protein O-linked glycosylation, response to drug, vascular endothelial growth factor receptor signaling pathway extracellular region, membrane, platelet alpha granule lumen growth factor activity, heparin binding, protein binding, protein heterodimerization activity, protein homodimerization activity Human VEGFC GOC UniProtKB {GO:0005515=PMID:21130043, GO:0008284=PMID:8617204, GO:0030947=GO_REF:0000019, GO:0006929=PMID:8617204, GO:0050714=GO_REF:0000019, GO:0060754=PMID:19275959, GO:0045776=GO_REF:0000019, GO:0005615=GO_REF:0000019, GO:1901492=GO_REF:0000019, GO:0009887=GO_REF:0000019, GO:0031093=Reactome:REACT_21351, GO:0051781=GO_REF:0000037, GO:0031954=GO_REF:0000019, GO:0050679=GO_REF:0000019, GO:0048010=Reactome:REACT_12529, GO:0042493=GO_REF:0000019, GO:0030168=Reactome:REACT_798, GO:0002052=GO_REF:0000019, GO:0005576=Reactome:REACT_21351, GO:0001525=GO_REF:0000019, GO:0042056=PMID:19275959, GO:0050918=PMID:19275959, GO:0050930=PMID:19275959, GO:0043536=GO_REF:0000019, GO:0007165=PMID:8617204, GO:0016331=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0007596=Reactome:REACT_604, GO:0002576=Reactome:REACT_318, GO:0043185=GO_REF:0000019, GO:0008083=GO_REF:0000037} P49767 Vascular endothelial growth factor C protein 20130413 {GO:0005515=IPI, GO:0008284=TAS, GO:0030947=IEA, GO:0006929=TAS, GO:0050714=IEA, GO:0060754=IDA, GO:0045776=IEA, GO:0005615=IEA, GO:1901492=IEA, GO:0009887=IEA, GO:0031093=TAS, GO:0051781=IEA, GO:0031954=IEA, GO:0050679=IEA, GO:0048010=TAS, GO:0042493=IEA, GO:0030168=TAS, GO:0002052=IEA, GO:0005576=TAS, GO:0001525=IEA, GO:0042056=IDA, GO:0050918=IDA, GO:0050930=IDA, GO:0043536=IEA, GO:0007165=TAS, GO:0016331=IEA, GO:0016020=IEA, GO:0007596=TAS, GO:0002576=TAS, GO:0043185=IEA, GO:0008083=IEA} angiogenesis, blood coagulation, induction of positive chemotaxis, morphogenesis of embryonic epithelium, negative regulation of blood pressure, organ morphogenesis, platelet activation, platelet degranulation, positive chemotaxis, positive regulation of blood vessel endothelial cell migration, positive regulation of cell division, positive regulation of cell proliferation, positive regulation of epithelial cell proliferation, positive regulation of lymphangiogenesis, positive regulation of mast cell chemotaxis, positive regulation of neuroblast proliferation, positive regulation of protein autophosphorylation, positive regulation of protein secretion, regulation of vascular endothelial growth factor receptor signaling pathway, response to drug, signal transduction, substrate-dependent cell migration, vascular endothelial growth factor receptor signaling pathway extracellular region, extracellular space, membrane, platelet alpha granule lumen chemoattractant activity, growth factor activity, protein binding, vascular endothelial growth factor receptor 3 binding Human VENTX UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037} O95231 Homeobox protein VENTX protein 20130413 {GO:0043565=IEA, GO:0003700=IEA, GO:0005634=IEA, GO:0007275=IEA} multicellular organismal development nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human UniProtKB-SubCell:SL-0191 VEPH1 UniProtKB UniProtKB {GO:0005543=GO_REF:0000002, GO:0005886=GO_REF:0000039} Q14D04 Ventricular zone-expressed PH domain-containing protein homolog 1 protein 20130413 {GO:0005543=IEA, GO:0005886=IEA} plasma membrane phospholipid binding Human UniProtKB-SubCell:SL-0039 VEZF1 HPA UniProtKB {GO:0006968=PMID:8035792, GO:0006366=PMID:8035792, GO:0006357=PMID:8035792, GO:0001885=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0001525=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037} Q14119 Vascular endothelial zinc finger 1 protein 20101115 {GO:0006968=TAS, GO:0006366=TAS, GO:0006357=TAS, GO:0001885=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0001525=IEA, GO:0003676=IEA, GO:0003677=IEA} angiogenesis, cellular defense response, endothelial cell development, regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter nucleolus, nucleus DNA binding, nucleic acid binding, zinc ion binding NOT Human VEZT UniProtKB UniProtKB {GO:0016337=GO_REF:0000019, GO:0005912=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0001669=GO_REF:0000039, GO:0002142=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0017022=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0043009=GO_REF:0000019} Q9HBM0 Vezatin protein 20130413 {GO:0016337=IEA, GO:0005912=IEA, GO:0005886=IEA, GO:0001669=IEA, GO:0002142=IEA, GO:0005634=IEA, GO:0017022=IEA, GO:0016021=IEA, GO:0043009=IEA} cell-cell adhesion, chordate embryonic development acrosomal vesicle, adherens junction, integral to membrane, nucleus, plasma membrane, stereocilia ankle link complex myosin binding Human UniProtKB-SubCell:SL-0009 VGF UniProtKB UniProtKB {GO:0030133=GO_REF:0000039, GO:0032868=GO_REF:0000019, GO:0009409=GO_REF:0000019, GO:0031410=PMID:17440014, GO:0006091=GO_REF:0000019, GO:0042593=GO_REF:0000019, GO:0005615=PMID:15706611, GO:0002021=GO_REF:0000019, GO:0051591=PMID:10381005, GO:0003674=GO_REF:0000015, GO:0019953=GO_REF:0000019, GO:0001541=GO_REF:0000019, GO:0005184=GO_REF:0000019, GO:0008083=GO_REF:0000037, GO:0030073=GO_REF:0000019, GO:0042742=GO_REF:0000037} O15240 Neurosecretory protein VGF protein 20080121 {GO:0030133=IEA, GO:0032868=IEA, GO:0009409=IEA, GO:0031410=IDA, GO:0006091=IEA, GO:0042593=IEA, GO:0005615=IDA, GO:0002021=IEA, GO:0051591=IEP, GO:0003674=ND, GO:0019953=IEA, GO:0001541=IEA, GO:0005184=IEA, GO:0008083=IEA, GO:0030073=IEA, GO:0042742=IEA} defense response to bacterium, generation of precursor metabolites and energy, glucose homeostasis, insulin secretion, ovarian follicle development, response to cAMP, response to cold, response to dietary excess, response to insulin stimulus, sexual reproduction cytoplasmic vesicle, extracellular space, transport vesicle growth factor activity, molecular_function, neuropeptide hormone activity Human VGLL1 UniProtKB UniProtKB {GO:0006355=PMID:10518497, GO:0003713=PMID:10518497, GO:0005634=PMID:10518497, GO:0006351=GO_REF:0000037} Q99990 Transcription cofactor vestigial-like protein 1 protein 20011005 {GO:0006355=NAS, GO:0003713=TAS, GO:0005634=NAS, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus transcription coactivator activity Human VGLL2 UniProtKB UniProtKB {GO:0005737=GO_REF:0000019, GO:0007519=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0003713=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q8N8G2 Transcription cofactor vestigial-like protein 2 protein 20130413 {GO:0005737=IEA, GO:0007519=IEA, GO:0045944=IEA, GO:0003713=IEA, GO:0005634=IEA, GO:0006351=IEA} positive regulation of transcription from RNA polymerase II promoter, skeletal muscle tissue development, transcription, DNA-dependent cytoplasm, nucleus transcription coactivator activity Human UniProtKB-SubCell:SL-0191 VGLL3 InterPro UniProtKB {GO:0006355=GO_REF:0000002, GO:0005634=GO_REF:0000002, GO:0006351=GO_REF:0000037} H7C571 Transcription cofactor vestigial-like protein 3 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus Human InterPro:IPR011520 VGLL4 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q14135 Transcription cofactor vestigial-like protein 4 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus Human UniProtKB-SubCell:SL-0191 VHL BHF-UCL UniProtKB {GO:0005515=PMID:21625219, GO:0004842=Reactome:REACT_121374, GO:0016567=PMID:12169691, GO:0008285=PMID:7660130, GO:0005783=PMID:12169691, GO:0045597=PMID:12169691, GO:0061418=Reactome:REACT_120815, GO:0005634=PMID:7604013, GO:0005829=Reactome:REACT_121002, GO:0005739=PMID:12169691, GO:0006508=PMID:10353251, GO:0043066=PMID:12169691, GO:0006355=PMID:15824735, GO:0006950=PMID:12169691, GO:0050821=PMID:12169691, GO:0071456=Reactome:REACT_121311, GO:0033554=Reactome:REACT_120956, GO:0000122=PMID:7660122, GO:0061428=PMID:11641274, GO:0000902=PMID:12169691, GO:0016020=GO_REF:0000039, GO:0005654=Reactome:REACT_121374, GO:0019899=PMID:11641274, GO:0045893=PMID:17973242, GO:0008134=PMID:11641274} P40337 Von Hippel-Lindau disease tumor suppressor protein 20080121 {GO:0005515=IPI, GO:0004842=TAS, GO:0016567=IMP, GO:0008285=TAS, GO:0005783=NAS, GO:0045597=NAS, GO:0061418=TAS, GO:0005634=TAS, GO:0005829=TAS, GO:0005739=NAS, GO:0006508=TAS, GO:0043066=NAS, GO:0006355=IMP, GO:0006950=NAS, GO:0050821=NAS, GO:0071456=TAS, GO:0033554=TAS, GO:0000122=TAS, GO:0061428=IDA, GO:0000902=NAS, GO:0016020=IEA, GO:0005654=TAS, GO:0019899=IPI, GO:0045893=IMP, GO:0008134=IPI} cell morphogenesis, cellular response to hypoxia, cellular response to stress, negative regulation of apoptotic process, negative regulation of cell proliferation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription from RNA polymerase II promoter in response to hypoxia, positive regulation of cell differentiation, positive regulation of transcription, DNA-dependent, protein stabilization, protein ubiquitination, proteolysis, regulation of transcription from RNA polymerase II promoter in response to hypoxia, regulation of transcription, DNA-dependent, response to stress cytosol, endoplasmic reticulum, membrane, mitochondrion, nucleoplasm, nucleus enzyme binding, protein binding, transcription factor binding, ubiquitin-protein ligase activity Human VHLL InterPro UniProtKB {GO:0016567=GO_REF:0000002, GO:0005634=GO_REF:0000002} Q6RSH7 Von Hippel-Lindau-like protein protein 20130413 {GO:0016567=IEA, GO:0005634=IEA} protein ubiquitination nucleus Human InterPro:IPR002714 VIL1 InterPro UniProtKB {GO:0005515=PMID:17229814, GO:0008360=PMID:16921170, GO:2000392=GO_REF:0000024, GO:0030175=PMID:15342783, GO:0032432=PMID:17182858, GO:0032433=GO_REF:0000024, GO:0042803=PMID:17606613, GO:0042802=PMID:17606613, GO:0051014=PMID:17182858, GO:0061041=GO_REF:0000024, GO:0009617=PMID:17182858, GO:0005737=GO_REF:0000037, GO:0051015=PMID:11500485, GO:0035727=PMID:19808673, GO:0007173=PMID:17229814, GO:0035729=GO_REF:0000019, GO:0032233=PMID:19808673, GO:0007010=GO_REF:0000002, GO:0030041=PMID:11500485, GO:0030042=PMID:11500485, GO:0043027=GO_REF:0000024, GO:0030335=PMID:16921170, GO:0005509=PMID:11500485, GO:0005546=PMID:14594952, GO:0003779=GO_REF:0000002, GO:0001726=PMID:17606613, GO:0030027=PMID:17606613, GO:0051693=PMID:17182858, GO:0005902=PMID:17182858, GO:0060327=PMID:15342783, GO:0006461=PMID:2846586, GO:0071364=PMID:17229814, GO:0051125=PMID:17182858, GO:0010634=PMID:17229814} Q96AC8 VIL1 protein protein 20130413 {GO:0005515=IPI, GO:0008360=IDA, GO:2000392=ISS, GO:0030175=IDA, GO:0032432=IDA, GO:0032433=ISS, GO:0042803=IDA, GO:0042802=IPI, GO:0051014=IDA, GO:0061041=ISS, GO:0009617=IDA, GO:0005737=IEA, GO:0051015=IDA, GO:0035727=IDA, GO:0007173=IDA, GO:0035729=IEA, GO:0032233=IDA, GO:0007010=IEA, GO:0030041=IDA, GO:0030042=IDA, GO:0043027=ISS, GO:0030335=IDA, GO:0005509=IDA, GO:0005546=IDA, GO:0003779=IEA, GO:0001726=IDA, GO:0030027=IDA, GO:0051693=IDA, GO:0005902=IDA, GO:0060327=IDA, GO:0006461=TAS, GO:0071364=IDA, GO:0051125=IDA, GO:0010634=IDA} actin filament capping, actin filament depolymerization, actin filament polymerization, actin filament severing, cellular response to epidermal growth factor stimulus, cellular response to hepatocyte growth factor stimulus, cytoplasmic actin-based contraction involved in cell motility, cytoskeleton organization, epidermal growth factor receptor signaling pathway, positive regulation of actin filament bundle assembly, positive regulation of cell migration, positive regulation of epithelial cell migration, protein complex assembly, regulation of actin nucleation, regulation of cell shape, regulation of lamellipodium morphogenesis, regulation of wound healing, response to bacterium actin filament bundle, cytoplasm, filopodium, filopodium tip, lamellipodium, microvillus, ruffle actin binding, actin filament binding, calcium ion binding, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, identical protein binding, lysophosphatidic acid binding, phosphatidylinositol-4,5-bisphosphate binding, protein binding, protein homodimerization activity Human InterPro:IPR007122 VIM UniProtKB UniProtKB {GO:0005882=GO_REF:0000038, GO:0005515=PMID:22300583, GO:0005212=GO_REF:0000019, GO:0045109=GO_REF:0000019, GO:0005886=PMID:19270731, GO:0070307=GO_REF:0000019, GO:0006928=PMID:16130169, GO:0042995=GO_REF:0000019, GO:0006921=Reactome:REACT_995, GO:0005829=Reactome:REACT_17057, GO:0042802=PMID:16169070, GO:0005737=PMID:9150946, GO:0097110=PMID:10852826, GO:0060020=GO_REF:0000019, GO:0045111=GO_REF:0000052, GO:0005856=PMID:16769727, GO:0031252=GO_REF:0000019, GO:0030049=Reactome:REACT_16969, GO:0006915=Reactome:REACT_578, GO:0008022=PMID:19270731, GO:0014002=GO_REF:0000019, GO:0005198=GO_REF:0000002, GO:0019048=GO_REF:0000037, GO:0005200=PMID:11889032, GO:0010977=GO_REF:0000019} Q5JVS8 Vimentin protein 20130413 {GO:0005882=IEA, GO:0005515=IPI, GO:0005212=IEA, GO:0045109=IEA, GO:0005886=IDA, GO:0070307=IEA, GO:0006928=TAS, GO:0042995=IEA, GO:0006921=TAS, GO:0005829=TAS, GO:0042802=IPI, GO:0005737=IDA, GO:0097110=IPI, GO:0060020=IEA, GO:0045111=IDA, GO:0005856=IDA, GO:0031252=IEA, GO:0030049=TAS, GO:0006915=TAS, GO:0008022=IPI, GO:0014002=IEA, GO:0005198=IEA, GO:0019048=IEA, GO:0005200=IDA, GO:0010977=IEA} Bergmann glial cell differentiation, apoptotic process, astrocyte development, cellular component disassembly involved in execution phase of apoptosis, cellular component movement, intermediate filament organization, lens fiber cell development, muscle filament sliding, negative regulation of neuron projection development, virus-host interaction cell leading edge, cell projection, cytoplasm, cytoskeleton, cytosol, intermediate filament, intermediate filament cytoskeleton, plasma membrane identical protein binding, protein C-terminus binding, protein binding, scaffold protein binding, structural constituent of cytoskeleton, structural constituent of eye lens, structural molecule activity Human UniProtKB-KW:KW-0403 VIP BHF-UCL UniProtKB {GO:0007589=PMID:4035357, GO:0045732=PMID:9603988, GO:0008284=PMID:8389448, GO:0043066=GO_REF:0000019, GO:0043267=GO_REF:0000019, GO:0010579=PMID:9603988, GO:0005576=Reactome:REACT_22268, GO:0048662=GO_REF:0000019, GO:0009966=GO_REF:0000019, GO:0032880=PMID:9603988, GO:0005179=PMID:9603988, GO:0001938=GO_REF:0000019, GO:0007186=PMID:10096039, GO:0045909=GO_REF:0000019, GO:0007611=GO_REF:0000019, GO:0043025=GO_REF:0000019, GO:0005184=PMID:10096039, GO:0051930=GO_REF:0000019} P01282 VIP peptides protein 20120323 {GO:0007589=TAS, GO:0045732=IDA, GO:0008284=TAS, GO:0043066=IEA, GO:0043267=IEA, GO:0010579=IDA, GO:0005576=TAS, GO:0048662=IEA, GO:0009966=IEA, GO:0032880=IDA, GO:0005179=IDA, GO:0001938=IEA, GO:0007186=TAS, GO:0045909=IEA, GO:0007611=IEA, GO:0043025=IEA, GO:0005184=TAS, GO:0051930=IEA} G-protein coupled receptor signaling pathway, body fluid secretion, learning or memory, negative regulation of apoptotic process, negative regulation of potassium ion transport, negative regulation of smooth muscle cell proliferation, positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway, positive regulation of cell proliferation, positive regulation of endothelial cell proliferation, positive regulation of protein catabolic process, positive regulation of vasodilation, regulation of protein localization, regulation of sensory perception of pain, regulation of signal transduction extracellular region, neuronal cell body hormone activity, neuropeptide hormone activity Human VIPR1 HPA UniProtKB {GO:0008284=PMID:8389448, GO:0005886=GO_REF:0000052, GO:0007586=PMID:8390245, GO:0005730=GO_REF:0000052, GO:0007268=PMID:8390245, GO:0005634=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0006955=PMID:8390245, GO:0006936=PMID:8390245, GO:0004999=GO_REF:0000002, GO:0007186=PMID:8179610, GO:0005887=PMID:8179610, GO:0007187=PMID:8390245, GO:0016021=GO_REF:0000038} P32241 Vasoactive intestinal polypeptide receptor 1 protein 20111111 {GO:0008284=TAS, GO:0005886=IDA, GO:0007586=TAS, GO:0005730=IDA, GO:0007268=TAS, GO:0005634=IDA, GO:0005737=IDA, GO:0006955=TAS, GO:0006936=TAS, GO:0004999=IEA, GO:0007186=TAS, GO:0005887=TAS, GO:0007187=TAS, GO:0016021=IEA} G-protein coupled receptor signaling pathway, G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, digestion, immune response, muscle contraction, positive regulation of cell proliferation, synaptic transmission cytoplasm, integral to membrane, integral to plasma membrane, nucleolus, nucleus, plasma membrane vasoactive intestinal polypeptide receptor activity Human VIPR2 UniProtKB UniProtKB {GO:0007165=PMID:7811244, GO:0007190=GO_REF:0000019, GO:0016020=GO_REF:0000002, GO:0005886=GO_REF:0000040, GO:0004999=GO_REF:0000002, GO:0005887=PMID:7811244, GO:0004930=PMID:7811244, GO:0007267=PMID:8757618, GO:0048662=GO_REF:0000019, GO:0016021=GO_REF:0000038} Q6ZN22 cDNA FLJ16511 fis, clone HEART2009680, highly similar to Vasoactive intestinal polypeptide receptor 2 protein 20130413 {GO:0007165=TAS, GO:0007190=IEA, GO:0016020=IEA, GO:0005886=IEA, GO:0004999=IEA, GO:0005887=TAS, GO:0004930=TAS, GO:0007267=TAS, GO:0048662=IEA, GO:0016021=IEA} activation of adenylate cyclase activity, cell-cell signaling, negative regulation of smooth muscle cell proliferation, signal transduction integral to membrane, integral to plasma membrane, membrane, plasma membrane G-protein coupled receptor activity, vasoactive intestinal polypeptide receptor activity Human UniProtKB-SubCell:SL-0039 VKORC1 Reactome UniProtKB {GO:0017187=Reactome:REACT_1132, GO:0005789=Reactome:REACT_950, GO:0016021=GO_REF:0000037, GO:0047057=GO_REF:0000003, GO:0044267=Reactome:REACT_17015, GO:0043687=Reactome:REACT_22161} Q9BQB6 Vitamin K epoxide reductase complex subunit 1 protein 20130301 {GO:0017187=TAS, GO:0005789=TAS, GO:0016021=IEA, GO:0047057=IEA, GO:0044267=TAS, GO:0043687=TAS} cellular protein metabolic process, peptidyl-glutamic acid carboxylation, post-translational protein modification endoplasmic reticulum membrane, integral to membrane vitamin-K-epoxide reductase (warfarin-sensitive) activity Human VKORC1L1 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8N0U8 Vitamin K epoxide reductase complex subunit 1-like protein 1 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 VLDLR UniProtKB UniProtKB {GO:0005515=PMID:8083232, GO:0005886=PMID:10380922, GO:0021517=GO_REF:0000019, GO:0005041=PMID:10380922, GO:0034361=GO_REF:0000037, GO:0001948=PMID:10571240, GO:0030229=PMID:8083232, GO:0045860=GO_REF:0000019, GO:0007613=PMID:7550352, GO:0034447=PMID:8083232, GO:1900006=GO_REF:0000024, GO:0008203=GO_REF:0000037, GO:0005509=GO_REF:0000002, GO:0000122=GO_REF:0000024, GO:0038026=GO_REF:0000024, GO:0006898=PMID:10571240, GO:0038025=GO_REF:0000024, GO:0007399=PMID:10380922, GO:0007165=PMID:10380922, GO:0005905=GO_REF:0000039, GO:0016020=PMID:15082773, GO:0006869=GO_REF:0000037, GO:0016021=GO_REF:0000038, GO:0034185=PMID:10571240, GO:0034436=PMID:10571240, GO:0034437=PMID:10571240, GO:0048306=PMID:10571240, GO:0034189=PMID:10571240} Q8NAN7 Very low-density lipoprotein receptor protein 20130413 {GO:0005515=IPI, GO:0005886=TAS, GO:0021517=IEA, GO:0005041=TAS, GO:0034361=IEA, GO:0001948=IPI, GO:0030229=IDA, GO:0045860=IEA, GO:0007613=TAS, GO:0034447=IDA, GO:1900006=ISS, GO:0008203=IEA, GO:0005509=IEA, GO:0000122=ISS, GO:0038026=ISS, GO:0006898=IDA, GO:0038025=ISS, GO:0007399=TAS, GO:0007165=TAS, GO:0005905=IEA, GO:0016020=IDA, GO:0006869=IEA, GO:0016021=IEA, GO:0034185=IDA, GO:0034436=IDA, GO:0034437=IDA, GO:0048306=IPI, GO:0034189=IDA} cholesterol metabolic process, glycoprotein transport, lipid transport, memory, negative regulation of transcription from RNA polymerase II promoter, nervous system development, positive regulation of dendrite development, positive regulation of protein kinase activity, receptor-mediated endocytosis, reelin-mediated signaling pathway, signal transduction, ventral spinal cord development, very-low-density lipoprotein particle clearance coated pit, integral to membrane, membrane, plasma membrane, very-low-density lipoprotein particle apolipoprotein binding, calcium ion binding, calcium-dependent protein binding, glycoprotein binding, glycoprotein transporter activity, low-density lipoprotein receptor activity, protein binding, reelin receptor activity, very-low-density lipoprotein particle binding, very-low-density lipoprotein particle receptor activity Human UniProtKB-KW:KW-0812 VMA21 LIFEdb UniProtKB {GO:0070072=PMID:19379691, GO:0030127=PMID:19379691, GO:0033116=GO_REF:0000039, GO:0005789=PMID:19379691, GO:0016021=GO_REF:0000037, GO:0005764=GO_REF:0000054} Q3ZAQ7 Vacuolar ATPase assembly integral membrane protein VMA21 protein 20100607 {GO:0070072=IDA, GO:0030127=IDA, GO:0033116=IEA, GO:0005789=IDA, GO:0016021=IEA, GO:0005764=IDA} vacuolar proton-transporting V-type ATPase complex assembly COPII vesicle coat, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment membrane, integral to membrane, lysosome Human VMP1 LIFEdb UniProtKB {GO:0005515=PMID:19056683, GO:0016337=PMID:17724469, GO:0005886=GO_REF:0000039, GO:0005783=GO_REF:0000054, GO:0007566=GO_REF:0000019, GO:0034329=PMID:17724469, GO:0033116=GO_REF:0000039, GO:0000421=GO_REF:0000024, GO:0006914=GO_REF:0000037, GO:0010506=GO_REF:0000024, GO:0000407=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q96GC9 Vacuole membrane protein 1 protein 20100607 {GO:0005515=IPI, GO:0016337=IMP, GO:0005886=IEA, GO:0005783=IDA, GO:0007566=IEA, GO:0034329=IMP, GO:0033116=IEA, GO:0000421=ISS, GO:0006914=IEA, GO:0010506=ISS, GO:0000407=IEA, GO:0016021=IEA} autophagy, cell junction assembly, cell-cell adhesion, embryo implantation, regulation of autophagy autophagic vacuole membrane, endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment membrane, integral to membrane, plasma membrane, pre-autophagosomal structure protein binding Human VNN2 BHF-UCL UniProtKB {GO:0017159=PMID:11491533, GO:0006807=GO_REF:0000002, GO:0015939=PMID:11491533, GO:0005886=GO_REF:0000039, GO:0016811=GO_REF:0000002, GO:0006928=PMID:9790769, GO:0031225=GO_REF:0000037} O95498 Vascular non-inflammatory molecule 2 protein 20080506 {GO:0017159=IDA, GO:0006807=IEA, GO:0015939=IDA, GO:0005886=IEA, GO:0016811=IEA, GO:0006928=TAS, GO:0031225=IEA} cellular component movement, nitrogen compound metabolic process, pantothenate metabolic process anchored to membrane, plasma membrane hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides, pantetheine hydrolase activity Human VOPP1 GOC UniProtKB {GO:0007165=PMID:12761501, GO:0006355=GO_REF:0000037, GO:0031301=PMID:20571887, GO:0004871=PMID:12761501, GO:0006351=GO_REF:0000037, GO:0030659=PMID:20571887, GO:0005768=GO_REF:0000054} Q96AW1 Vesicular, overexpressed in cancer, prosurvival protein 1 protein 20130413 {GO:0007165=IMP, GO:0006355=IEA, GO:0031301=IDA, GO:0004871=IMP, GO:0006351=IEA, GO:0030659=IDA, GO:0005768=IDA} regulation of transcription, DNA-dependent, signal transduction, transcription, DNA-dependent cytoplasmic vesicle membrane, endosome, integral to organelle membrane signal transducer activity Human VPRBP IntAct UniProtKB {GO:0005515=PMID:22190034, GO:0005737=GO_REF:0000039, GO:0016567=GO_REF:0000041, GO:0008180=PMID:18850735, GO:0019048=GO_REF:0000037, GO:0005634=PMID:20178741} Q9Y4B6 Protein VPRBP protein 20130415 {GO:0005515=IPI, GO:0005737=IEA, GO:0016567=IEA, GO:0008180=IDA, GO:0019048=IEA, GO:0005634=IDA} protein ubiquitination, virus-host interaction cytoplasm, nucleus, signalosome protein binding Human UniProtKB:P12520 VPREB1 UniProtKB UniProtKB {GO:0006955=GO_REF:0000029, GO:0005576=GO_REF:0000029, GO:0003823=GO_REF:0000029} P12018 Immunoglobulin iota chain protein 20021104 {GO:0006955=NAS, GO:0005576=NAS, GO:0003823=NAS} immune response extracellular region antigen binding Human VPREB3 PINC UniProtKB {GO:0005783=PMID:10702669} Q9UKI3 Pre-B lymphocyte protein 3 protein 20040811 {GO:0005783=NAS} endoplasmic reticulum Human VPS11 IntAct UniProtKB {GO:0005515=PMID:22493164, GO:0030897=PMID:19109425, GO:0000166=GO_REF:0000037, GO:0031902=GO_REF:0000039, GO:0030139=PMID:20682791, GO:0008270=GO_REF:0000002, GO:0005765=GO_REF:0000039, GO:0016192=GO_REF:0000002, GO:0006886=GO_REF:0000002, GO:0005768=PMID:20682791} Q9H270 Vacuolar protein sorting-associated protein 11 homolog protein 20130415 {GO:0005515=IPI, GO:0030897=IDA, GO:0000166=IEA, GO:0031902=IEA, GO:0030139=IDA, GO:0008270=IEA, GO:0005765=IEA, GO:0016192=IEA, GO:0006886=IEA, GO:0005768=IDA} intracellular protein transport, vesicle-mediated transport HOPS complex, endocytic vesicle, endosome, late endosome membrane, lysosomal membrane nucleotide binding, protein binding, zinc ion binding Human UniProtKB:P35226 VPS13A IntAct UniProtKB {GO:0005515=PMID:17474147, GO:0005622=PMID:11381254, GO:0008219=GO_REF:0000037, GO:0008104=PMID:11381254, GO:0035176=GO_REF:0000019, GO:0007626=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0006895=PMID:11381253, GO:0007399=GO_REF:0000019} Q96RL7 Vacuolar protein sorting-associated protein 13A protein 20130415 {GO:0005515=IPI, GO:0005622=NAS, GO:0008219=IEA, GO:0008104=NAS, GO:0035176=IEA, GO:0007626=IEA, GO:0015031=IEA, GO:0006895=NAS, GO:0007399=IEA} Golgi to endosome transport, cell death, locomotory behavior, nervous system development, protein localization, protein transport, social behavior intracellular protein binding Human UniProtKB:P16333 VPS13B UniProtKB UniProtKB {GO:0015031=GO_REF:0000037} Q7Z7G8 Vacuolar protein sorting-associated protein 13B protein 20130413 {GO:0015031=IEA} protein transport Human UniProtKB-KW:KW-0653 VPS13C null null {} null null null null {} null null null VPS13D null null {} null null null null {} null null null VPS16 UniProtKB UniProtKB {GO:0030424=GO_REF:0000019, GO:0030897=PMID:19109425, GO:0005737=GO_REF:0000002, GO:0051015=GO_REF:0000019, GO:0005770=PMID:19109425, GO:0005884=GO_REF:0000019, GO:0031902=GO_REF:0000039, GO:0043025=GO_REF:0000019, GO:0055037=PMID:19109425, GO:0005765=GO_REF:0000039, GO:0006886=GO_REF:0000002, GO:0005769=PMID:19109425} Q9H269 Vacuolar protein sorting-associated protein 16 homolog protein 20090827 {GO:0030424=IEA, GO:0030897=IDA, GO:0005737=IEA, GO:0051015=IEA, GO:0005770=IDA, GO:0005884=IEA, GO:0031902=IEA, GO:0043025=IEA, GO:0055037=IDA, GO:0005765=IEA, GO:0006886=IEA, GO:0005769=IDA} intracellular protein transport HOPS complex, actin filament, axon, cytoplasm, early endosome, late endosome, late endosome membrane, lysosomal membrane, neuronal cell body, recycling endosome actin filament binding Human VPS18 IntAct UniProtKB {GO:0005515=PMID:20434987, GO:0030897=PMID:19109425, GO:0005884=GO_REF:0000019, GO:0031902=GO_REF:0000039, GO:0007032=PMID:18799622, GO:0003779=GO_REF:0000019, GO:0005765=GO_REF:0000039, GO:0016192=GO_REF:0000002, GO:0007040=PMID:18799622, GO:0006886=GO_REF:0000002, GO:0005769=GO_REF:0000019, GO:0046872=GO_REF:0000037} Q9P253 Vacuolar protein sorting-associated protein 18 homolog protein 20130415 {GO:0005515=IPI, GO:0030897=IDA, GO:0005884=IEA, GO:0031902=IEA, GO:0007032=IDA, GO:0003779=IEA, GO:0005765=IEA, GO:0016192=IEA, GO:0007040=IDA, GO:0006886=IEA, GO:0005769=IEA, GO:0046872=IEA} endosome organization, intracellular protein transport, lysosome organization, vesicle-mediated transport HOPS complex, actin filament, early endosome, late endosome membrane, lysosomal membrane actin binding, metal ion binding, protein binding Human UniProtKB:Q7L1V2 VPS25 Reactome UniProtKB {GO:0005739=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0016197=Reactome:REACT_27258, GO:0005654=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0016044=Reactome:REACT_11123, GO:0010008=GO_REF:0000039, GO:0006351=GO_REF:0000037, GO:0005829=Reactome:REACT_27319} Q9BRG1 Vacuolar protein-sorting-associated protein 25 protein 20100729 {GO:0005739=IEA, GO:0006355=IEA, GO:0016197=TAS, GO:0005654=IEA, GO:0015031=IEA, GO:0016044=TAS, GO:0010008=IEA, GO:0006351=IEA, GO:0005829=TAS} cellular membrane organization, endosomal transport, protein transport, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytosol, endosome membrane, mitochondrion, nucleoplasm Human VPS26A UniProtKB UniProtKB {GO:0005515=PMID:11102511, GO:0007034=GO_REF:0000002, GO:0008565=PMID:11102511, GO:0042147=PMID:11102511, GO:0031982=PMID:20682791, GO:0010008=GO_REF:0000039, GO:0005829=PMID:11102511, GO:0005768=PMID:20682791, GO:0030904=GO_REF:0000002} O75436 Vacuolar protein sorting-associated protein 26A protein 20110629 {GO:0005515=IPI, GO:0007034=IEA, GO:0008565=NAS, GO:0042147=NAS, GO:0031982=IDA, GO:0010008=IEA, GO:0005829=IDA, GO:0005768=IDA, GO:0030904=IEA} retrograde transport, endosome to Golgi, vacuolar transport cytosol, endosome, endosome membrane, retromer complex, vesicle protein binding, protein transporter activity Human VPS26B UniProtKB UniProtKB {GO:0007034=GO_REF:0000002, GO:0015031=GO_REF:0000037, GO:0005829=PMID:11102511, GO:0030904=GO_REF:0000002} Q4G0F5 Vacuolar protein sorting-associated protein 26B protein 20061106 {GO:0007034=IEA, GO:0015031=IEA, GO:0005829=ISS, GO:0030904=IEA} protein transport, vacuolar transport cytosol, retromer complex Human UniProtKB:O75436 VPS28 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0022415=Reactome:REACT_6361, GO:0005886=GO_REF:0000039, GO:0019082=Reactome:REACT_115860, GO:0019068=Reactome:REACT_6818, GO:0015031=GO_REF:0000037, GO:0005829=PMID:11134028, GO:0046788=Reactome:REACT_115893, GO:0005737=PMID:18077552, GO:0031902=GO_REF:0000039, GO:0016197=Reactome:REACT_27258, GO:0016032=Reactome:REACT_6256, GO:0031397=PMID:18077552, GO:0010008=Reactome:REACT_115855, GO:0016044=Reactome:REACT_11123, GO:0005768=PMID:11134028} Q9UK41 Vacuolar protein sorting-associated protein 28 homolog protein 20130415 {GO:0005515=IPI, GO:0022415=TAS, GO:0005886=IEA, GO:0019082=TAS, GO:0019068=TAS, GO:0015031=IEA, GO:0005829=IDA, GO:0046788=TAS, GO:0005737=IDA, GO:0031902=IEA, GO:0016197=TAS, GO:0016032=TAS, GO:0031397=IDA, GO:0010008=TAS, GO:0016044=TAS, GO:0005768=IDA} cellular membrane organization, egress of virus within host cell, endosomal transport, negative regulation of protein ubiquitination, protein transport, viral protein processing, viral reproduction, viral reproductive process, virion assembly cytoplasm, cytosol, endosome, endosome membrane, late endosome membrane, plasma membrane protein binding Human UniProtKB:Q99816 VPS29 LIFEdb UniProtKB {GO:0016788=GO_REF:0000002, GO:0015031=GO_REF:0000037, GO:0010008=GO_REF:0000039, GO:0046872=GO_REF:0000037, GO:0004647=GO_REF:0000003, GO:0005768=GO_REF:0000054} Q9UBQ0 Vacuolar protein sorting-associated protein 29 protein 20100607 {GO:0016788=IEA, GO:0015031=IEA, GO:0010008=IEA, GO:0046872=IEA, GO:0004647=IEA, GO:0005768=IDA} protein transport endosome, endosome membrane hydrolase activity, acting on ester bonds, metal ion binding, phosphoserine phosphatase activity Human VPS33A MGI UniProtKB {GO:0005515=PMID:19109425, GO:0032418=PMID:15790593, GO:0048471=PMID:19109425, GO:0030897=PMID:19109425, GO:0005770=PMID:19109425, GO:0032400=PMID:15790593, GO:0015031=GO_REF:0000037, GO:0005765=GO_REF:0000039, GO:0006904=GO_REF:0000002, GO:0048070=GO_REF:0000024, GO:0031902=GO_REF:0000039, GO:0016192=PMID:15790593, GO:0005769=PMID:19109425, GO:0030220=GO_REF:0000024} Q96AX1 Vacuolar protein sorting-associated protein 33A protein 20091111 {GO:0005515=IPI, GO:0032418=IDA, GO:0048471=IDA, GO:0030897=IDA, GO:0005770=IDA, GO:0032400=IDA, GO:0015031=IEA, GO:0005765=IEA, GO:0006904=IEA, GO:0048070=ISS, GO:0031902=IEA, GO:0016192=IDA, GO:0005769=IDA, GO:0030220=ISS} lysosome localization, melanosome localization, platelet formation, protein transport, regulation of developmental pigmentation, vesicle docking involved in exocytosis, vesicle-mediated transport HOPS complex, early endosome, late endosome, late endosome membrane, lysosomal membrane, perinuclear region of cytoplasm protein binding Human VPS33B MGI UniProtKB {GO:0005515=PMID:19109425, GO:0032418=PMID:15790593, GO:0030897=PMID:19109425, GO:0048471=PMID:19109425, GO:0005770=PMID:15052268, GO:0032400=PMID:15790593, GO:0070889=PMID:16123220, GO:0005765=GO_REF:0000039, GO:0015031=PMID:15052268, GO:0005764=PMID:15052268, GO:0006904=GO_REF:0000002, GO:0005737=PMID:20190753, GO:0006944=PMID:15052268, GO:0031902=GO_REF:0000039, GO:0031091=PMID:16123220, GO:0016192=PMID:15790593} Q9H267 Vacuolar protein sorting-associated protein 33B protein 20060414 {GO:0005515=IPI, GO:0032418=IDA, GO:0030897=IDA, GO:0048471=IDA, GO:0005770=IDA, GO:0032400=IDA, GO:0070889=IMP, GO:0005765=IEA, GO:0015031=IMP, GO:0005764=IDA, GO:0006904=IEA, GO:0005737=IDA, GO:0006944=IMP, GO:0031902=IEA, GO:0031091=IDA, GO:0016192=IDA} cellular membrane fusion, lysosome localization, melanosome localization, platelet alpha granule organization, protein transport, vesicle docking involved in exocytosis, vesicle-mediated transport HOPS complex, cytoplasm, late endosome, late endosome membrane, lysosomal membrane, lysosome, perinuclear region of cytoplasm, platelet alpha granule protein binding Human VPS35 HPA UniProtKB {GO:0005515=PMID:19553991, GO:0008219=GO_REF:0000037, GO:0016020=GO_REF:0000039, GO:0042147=PMID:11102511, GO:0015031=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0005768=GO_REF:0000054, GO:0005829=PMID:11102511} Q96QK1 Vacuolar protein sorting-associated protein 35 protein 20120912 {GO:0005515=IPI, GO:0008219=IEA, GO:0016020=IEA, GO:0042147=NAS, GO:0015031=IEA, GO:0043231=IDA, GO:0005768=IDA, GO:0005829=IDA} cell death, protein transport, retrograde transport, endosome to Golgi cytosol, endosome, intracellular membrane-bounded organelle, membrane protein binding Human VPS36 Reactome UniProtKB {GO:0043130=GO_REF:0000019, GO:0006355=GO_REF:0000037, GO:0005770=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0032266=GO_REF:0000002, GO:0015031=GO_REF:0000037, GO:0005764=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0005829=Reactome:REACT_27319, GO:0016020=GO_REF:0000039, GO:0016197=Reactome:REACT_27258, GO:0016044=Reactome:REACT_11123, GO:0005768=PMID:20682791} Q86VN1 Vacuolar protein-sorting-associated protein 36 protein 20100729 {GO:0043130=IEA, GO:0006355=IEA, GO:0005770=IEA, GO:0005634=IEA, GO:0032266=IEA, GO:0015031=IEA, GO:0005764=IEA, GO:0006351=IEA, GO:0005829=TAS, GO:0016020=IEA, GO:0016197=TAS, GO:0016044=TAS, GO:0005768=IDA} cellular membrane organization, endosomal transport, protein transport, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytosol, endosome, late endosome, lysosome, membrane, nucleus phosphatidylinositol-3-phosphate binding, ubiquitin binding Human VPS37A HPA UniProtKB {GO:0022415=Reactome:REACT_6361, GO:0008219=GO_REF:0000037, GO:0005813=GO_REF:0000052, GO:0019082=Reactome:REACT_115860, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0019068=Reactome:REACT_6818, GO:0015031=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0046788=Reactome:REACT_115893, GO:0005737=GO_REF:0000052, GO:0031902=GO_REF:0000039, GO:0016197=Reactome:REACT_27258, GO:0016032=Reactome:REACT_6256, GO:0010008=Reactome:REACT_115855, GO:0016044=Reactome:REACT_11123} Q8NEZ2 Vacuolar protein sorting-associated protein 37A protein 20101115 {GO:0022415=TAS, GO:0008219=IEA, GO:0005813=IDA, GO:0019082=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0019068=TAS, GO:0015031=IEA, GO:0043231=IDA, GO:0046788=TAS, GO:0005737=IDA, GO:0031902=IEA, GO:0016197=TAS, GO:0016032=TAS, GO:0010008=TAS, GO:0016044=TAS} cell death, cellular membrane organization, egress of virus within host cell, endosomal transport, protein transport, viral protein processing, viral reproduction, viral reproductive process, virion assembly centrosome, cytoplasm, endosome membrane, intracellular membrane-bounded organelle, late endosome membrane, nucleolus, nucleus Human VPS37B Reactome UniProtKB {GO:0005515=PMID:19129479, GO:0046788=Reactome:REACT_115893, GO:0022415=Reactome:REACT_6361, GO:0019082=Reactome:REACT_115860, GO:0016197=Reactome:REACT_27258, GO:0031902=GO_REF:0000039, GO:0016032=Reactome:REACT_6256, GO:0030496=PMID:19129479, GO:0019068=Reactome:REACT_6818, GO:0015031=GO_REF:0000037, GO:0016044=Reactome:REACT_11123, GO:0010008=Reactome:REACT_115855} Q9H9H4 Vacuolar protein sorting-associated protein 37B protein 20130214 {GO:0005515=IPI, GO:0046788=TAS, GO:0022415=TAS, GO:0019082=TAS, GO:0016197=TAS, GO:0031902=IEA, GO:0016032=TAS, GO:0030496=IDA, GO:0019068=TAS, GO:0015031=IEA, GO:0016044=TAS, GO:0010008=TAS} cellular membrane organization, egress of virus within host cell, endosomal transport, protein transport, viral protein processing, viral reproduction, viral reproductive process, virion assembly endosome membrane, late endosome membrane, midbody protein binding Human VPS37C HPA UniProtKB {GO:0046788=Reactome:REACT_115893, GO:0022415=Reactome:REACT_6361, GO:0019082=Reactome:REACT_115860, GO:0016197=Reactome:REACT_27258, GO:0031902=GO_REF:0000039, GO:0016032=Reactome:REACT_6256, GO:0005634=GO_REF:0000052, GO:0019068=Reactome:REACT_6818, GO:0015031=GO_REF:0000037, GO:0016044=Reactome:REACT_11123, GO:0010008=Reactome:REACT_115855, GO:0043231=GO_REF:0000052} A5D8V6 Vacuolar protein sorting-associated protein 37C protein 20111111 {GO:0046788=TAS, GO:0022415=TAS, GO:0019082=TAS, GO:0016197=TAS, GO:0031902=IEA, GO:0016032=TAS, GO:0005634=IDA, GO:0019068=TAS, GO:0015031=IEA, GO:0016044=TAS, GO:0010008=TAS, GO:0043231=IDA} cellular membrane organization, egress of virus within host cell, endosomal transport, protein transport, viral protein processing, viral reproduction, viral reproductive process, virion assembly endosome membrane, intracellular membrane-bounded organelle, late endosome membrane, nucleus Human VPS37D Reactome UniProtKB {GO:0046788=Reactome:REACT_115893, GO:0022415=Reactome:REACT_6361, GO:0019082=Reactome:REACT_115860, GO:0016197=Reactome:REACT_27258, GO:0031902=GO_REF:0000039, GO:0016032=Reactome:REACT_6256, GO:0019068=Reactome:REACT_6818, GO:0015031=GO_REF:0000037, GO:0016044=Reactome:REACT_11123, GO:0010008=Reactome:REACT_115855} Q86XT2 Vacuolar protein sorting-associated protein 37D protein 20130214 {GO:0046788=TAS, GO:0022415=TAS, GO:0019082=TAS, GO:0016197=TAS, GO:0031902=IEA, GO:0016032=TAS, GO:0019068=TAS, GO:0015031=IEA, GO:0016044=TAS, GO:0010008=TAS} cellular membrane organization, egress of virus within host cell, endosomal transport, protein transport, viral protein processing, viral reproduction, viral reproductive process, virion assembly endosome membrane, late endosome membrane Human VPS39 UniProtKB UniProtKB {GO:0030897=PMID:19109425, GO:0005083=GO_REF:0000002, GO:0031902=GO_REF:0000039, GO:0005765=GO_REF:0000039, GO:0015031=GO_REF:0000037} Q96JC1 Vam6/Vps39-like protein protein 20090827 {GO:0030897=IDA, GO:0005083=IEA, GO:0031902=IEA, GO:0005765=IEA, GO:0015031=IEA} protein transport HOPS complex, late endosome membrane, lysosomal membrane small GTPase regulator activity Human VPS41 IntAct UniProtKB {GO:0005515=PMID:19109425, GO:0008017=GO_REF:0000019, GO:0030897=PMID:19109425, GO:0005770=GO_REF:0000019, GO:0005874=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0016192=GO_REF:0000002, GO:0006886=GO_REF:0000002, GO:0005769=GO_REF:0000019} P49754 Vacuolar protein sorting-associated protein 41 homolog protein 20130415 {GO:0005515=IPI, GO:0008017=IEA, GO:0030897=IDA, GO:0005770=IEA, GO:0005874=IEA, GO:0008270=IEA, GO:0016192=IEA, GO:0006886=IEA, GO:0005769=IEA} intracellular protein transport, vesicle-mediated transport HOPS complex, early endosome, late endosome, microtubule microtubule binding, protein binding, zinc ion binding Human UniProtKB:Q9H9C1 VPS45 BHF-UCL UniProtKB {GO:0003674=GO_REF:0000015, GO:0005794=GO_REF:0000024, GO:0000139=GO_REF:0000039, GO:0007596=Reactome:REACT_604, GO:0016021=GO_REF:0000024, GO:0005575=GO_REF:0000015, GO:0006886=PMID:10404641, GO:0010008=Reactome:REACT_24949, GO:0006904=GO_REF:0000002} Q9NRW7 Vacuolar protein sorting-associated protein 45 protein 20120828 {GO:0003674=ND, GO:0005794=ISS, GO:0000139=IEA, GO:0007596=TAS, GO:0016021=ISS, GO:0005575=ND, GO:0006886=NAS, GO:0010008=TAS, GO:0006904=IEA} blood coagulation, intracellular protein transport, vesicle docking involved in exocytosis Golgi apparatus, Golgi membrane, cellular_component, endosome membrane, integral to membrane molecular_function Human UniProtKB:O08700 VPS4A Reactome UniProtKB {GO:0005515=PMID:11559748, GO:0000815=PMID:18606141, GO:0048471=PMID:11563910, GO:0042623=PMID:16174732, GO:0019904=PMID:18606141, GO:0030496=PMID:19129479, GO:0015031=GO_REF:0000037, GO:0008022=PMID:17928862, GO:0005524=GO_REF:0000037, GO:0005829=Reactome:REACT_27184, GO:0000910=PMID:17853893, GO:0007049=GO_REF:0000037, GO:0005737=PMID:11563910, GO:0031902=GO_REF:0000039, GO:0016197=Reactome:REACT_27258, GO:0016192=PMID:11563910, GO:0016044=Reactome:REACT_11123} Q9UN37 Vacuolar protein sorting-associated protein 4A protein 20100729 {GO:0005515=IPI, GO:0000815=IDA, GO:0048471=IDA, GO:0042623=NAS, GO:0019904=IPI, GO:0030496=IDA, GO:0015031=IEA, GO:0008022=IPI, GO:0005524=IEA, GO:0005829=TAS, GO:0000910=IDA, GO:0007049=IEA, GO:0005737=IDA, GO:0031902=IEA, GO:0016197=TAS, GO:0016192=IDA, GO:0016044=TAS} cell cycle, cellular membrane organization, cytokinesis, endosomal transport, protein transport, vesicle-mediated transport ESCRT III complex, cytoplasm, cytosol, late endosome membrane, midbody, perinuclear region of cytoplasm ATP binding, ATPase activity, coupled, protein C-terminus binding, protein binding, protein domain specific binding Human VPS4B Reactome UniProtKB {GO:0005515=PMID:19129479, GO:0006200=PMID:10637304, GO:0042623=PMID:16174732, GO:0033993=PMID:16757520, GO:0005634=PMID:16757520, GO:0015031=GO_REF:0000037, GO:0005764=PMID:10637304, GO:0005829=Reactome:REACT_27184, GO:0005737=PMID:16757520, GO:0016197=Reactome:REACT_27258, GO:0007032=GO_REF:0000019, GO:0016887=PMID:11563910, GO:0006813=GO_REF:0000019, GO:0005774=PMID:10637304, GO:0005770=PMID:10637304, GO:0008022=PMID:17928862, GO:0005524=PMID:10637304, GO:0007049=GO_REF:0000037, GO:0032510=PMID:15024011, GO:0031902=GO_REF:0000039, GO:0016044=Reactome:REACT_11123, GO:0005769=PMID:10637304, GO:0032367=PMID:10637304, GO:0010008=PMID:16757520, GO:0051301=GO_REF:0000037, GO:0005768=PMID:11563910} O75351 Vacuolar protein sorting-associated protein 4B protein 20100729 {GO:0005515=IPI, GO:0006200=IMP, GO:0042623=NAS, GO:0033993=IDA, GO:0005634=IDA, GO:0015031=IEA, GO:0005764=IDA, GO:0005829=TAS, GO:0005737=IDA, GO:0016197=TAS, GO:0007032=IEA, GO:0016887=IDA, GO:0006813=IEA, GO:0005774=IDA, GO:0005770=IDA, GO:0008022=IPI, GO:0005524=IMP, GO:0007049=IEA, GO:0032510=IMP, GO:0031902=IEA, GO:0016044=TAS, GO:0005769=IDA, GO:0032367=IMP, GO:0010008=IDA, GO:0051301=IEA, GO:0005768=IDA} ATP catabolic process, cell cycle, cell division, cellular membrane organization, endosomal transport, endosome organization, endosome to lysosome transport via multivesicular body sorting pathway, intracellular cholesterol transport, potassium ion transport, protein transport, response to lipid cytoplasm, cytosol, early endosome, endosome, endosome membrane, late endosome, late endosome membrane, lysosome, nucleus, vacuolar membrane ATP binding, ATPase activity, ATPase activity, coupled, protein C-terminus binding, protein binding Human VPS52 UniProtKB UniProtKB {GO:0005515=PMID:20685960, GO:0005794=GO_REF:0000039, GO:0015031=GO_REF:0000037, GO:0010008=GO_REF:0000039} Q8N1B4 Vacuolar protein sorting-associated protein 52 homolog protein 20120803 {GO:0005515=IPI, GO:0005794=IEA, GO:0015031=IEA, GO:0010008=IEA} protein transport Golgi apparatus, endosome membrane protein binding Human UniProtKB:Q9UID3 VPS53 MGI UniProtKB {GO:0005515=PMID:20685960, GO:0015031=GO_REF:0000037, GO:0010008=GO_REF:0000039, GO:0000938=PMID:19620288} Q5VIR6 Vacuolar protein sorting-associated protein 53 homolog protein 20121002 {GO:0005515=IPI, GO:0015031=IEA, GO:0010008=IEA, GO:0000938=IDA} protein transport GARP complex, endosome membrane protein binding Human VPS54 MGI UniProtKB {GO:0005515=PMID:20685960, GO:0060052=GO_REF:0000019, GO:0048873=GO_REF:0000019, GO:0050881=GO_REF:0000019, GO:0042147=GO_REF:0000002, GO:0015031=GO_REF:0000037, GO:0040007=GO_REF:0000019, GO:0000938=PMID:19620288} Q9P1Q0 Vacuolar protein sorting-associated protein 54 protein 20121002 {GO:0005515=IPI, GO:0060052=IEA, GO:0048873=IEA, GO:0050881=IEA, GO:0042147=IEA, GO:0015031=IEA, GO:0040007=IEA, GO:0000938=IDA} growth, homeostasis of number of cells within a tissue, musculoskeletal movement, neurofilament cytoskeleton organization, protein transport, retrograde transport, endosome to Golgi GARP complex protein binding Human VPS72 IntAct UniProtKB {GO:0005515=PMID:16230350, GO:0043234=PMID:14966270, GO:0006355=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0000122=PMID:7702631, GO:0035019=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0016568=GO_REF:0000037} Q15906 Vacuolar protein sorting-associated protein 72 homolog protein 20130415 {GO:0005515=IPI, GO:0043234=IDA, GO:0006355=IEA, GO:0005634=IEA, GO:0000122=TAS, GO:0035019=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0016568=IEA} chromatin modification, negative regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, somatic stem cell maintenance, transcription, DNA-dependent nucleus, protein complex DNA binding, protein binding Human UniProtKB:Q9Y265 VPS8 InterPro UniProtKB {GO:0008270=GO_REF:0000002} Q8N3P4 Vacuolar protein sorting-associated protein 8 homolog protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR001841 VRK1 HPA UniProtKB {GO:0005515=PMID:22621922, GO:0007077=Reactome:REACT_160255, GO:0005795=PMID:19103756, GO:0007084=Reactome:REACT_160113, GO:0005730=GO_REF:0000052, GO:0005819=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0090166=PMID:19103756, GO:0005524=GO_REF:0000037, GO:0042802=PMID:22621922, GO:0005829=Reactome:REACT_160159, GO:0005737=GO_REF:0000052, GO:0046777=PMID:21543316, GO:0000088=Reactome:REACT_765, GO:0004674=PMID:21543316, GO:0000087=Reactome:REACT_910, GO:0005654=Reactome:REACT_160221, GO:0006468=PMID:9344656, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0016772=GO_REF:0000002, GO:0051301=GO_REF:0000037} Q99986 Serine/threonine-protein kinase VRK1 protein 20101115 {GO:0005515=IPI, GO:0007077=TAS, GO:0005795=IDA, GO:0007084=TAS, GO:0005730=IDA, GO:0005819=IEA, GO:0005634=IDA, GO:0090166=IDA, GO:0005524=IEA, GO:0042802=IPI, GO:0005829=TAS, GO:0005737=IDA, GO:0046777=IDA, GO:0000088=TAS, GO:0004674=IDA, GO:0000087=TAS, GO:0005654=TAS, GO:0006468=TAS, GO:0000278=TAS, GO:0000090=TAS, GO:0016772=IEA, GO:0051301=IEA} Golgi disassembly, M phase of mitotic cell cycle, cell division, mitotic anaphase, mitotic cell cycle, mitotic nuclear envelope disassembly, mitotic nuclear envelope reassembly, mitotic prophase, protein autophosphorylation, protein phosphorylation Golgi stack, cytoplasm, cytosol, nucleolus, nucleoplasm, nucleus, spindle ATP binding, identical protein binding, protein binding, protein serine/threonine kinase activity, transferase activity, transferring phosphorus-containing groups Human VRK2 IntAct UniProtKB {GO:0005515=PMID:20679487, GO:0031966=PMID:18286207, GO:0005634=PMID:16704422, GO:2000659=PMID:18286207, GO:0005524=GO_REF:0000037, GO:0005737=PMID:16704422, GO:0046777=PMID:14645249, GO:0004674=PMID:16495336, GO:0019048=GO_REF:0000037, GO:0043408=PMID:20679487, GO:0005789=PMID:18286207, GO:0006468=PMID:9344656, GO:0016021=GO_REF:0000037, GO:0034599=PMID:17709393} Q86Y07 Serine/threonine-protein kinase VRK2 protein 20130415 {GO:0005515=IPI, GO:0031966=IDA, GO:0005634=IDA, GO:2000659=IMP, GO:0005524=IEA, GO:0005737=IDA, GO:0046777=IDA, GO:0004674=IDA, GO:0019048=IEA, GO:0043408=IMP, GO:0005789=IDA, GO:0006468=TAS, GO:0016021=IEA, GO:0034599=IMP} cellular response to oxidative stress, protein autophosphorylation, protein phosphorylation, regulation of MAPK cascade, regulation of interleukin-1-mediated signaling pathway, virus-host interaction cytoplasm, endoplasmic reticulum membrane, integral to membrane, mitochondrial membrane, nucleus ATP binding, protein binding, protein serine/threonine kinase activity Human UniProtKB:Q02750 VRK3 UniProtKB UniProtKB {GO:0004672=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0005524=GO_REF:0000002} Q8IV63 Inactive serine/threonine-protein kinase VRK3 protein 20130413 {GO:0004672=IEA, GO:0005634=IEA, GO:0005524=IEA} nucleus ATP binding, protein kinase activity Human UniProtKB-SubCell:SL-0191 VSIG10 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8N0Z9 V-set and immunoglobulin domain-containing protein 10 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 VSIG4 ENSEMBL UniProtKB {GO:0032703=GO_REF:0000019, GO:0006957=GO_REF:0000037, GO:0016021=GO_REF:0000037, GO:0042130=GO_REF:0000019} Q9Y279 V-set and immunoglobulin domain-containing protein 4 protein 20130413 {GO:0032703=IEA, GO:0006957=IEA, GO:0016021=IEA, GO:0042130=IEA} complement activation, alternative pathway, negative regulation of T cell proliferation, negative regulation of interleukin-2 production integral to membrane Human Ensembl:ENSMUSP00000051521 VSIG8 ENSEMBL UniProtKB {GO:0005622=GO_REF:0000019, GO:0016021=GO_REF:0000037} Q5VU13 V-set and immunoglobulin domain-containing protein 8 protein 20130413 {GO:0005622=IEA, GO:0016021=IEA} integral to membrane, intracellular Human Ensembl:ENSMUSP00000058008 VSNL1 InterPro UniProtKB {GO:0005509=GO_REF:0000002} P62760 Visinin-like protein 1 protein 20130413 {GO:0005509=IEA} calcium ion binding Human InterPro:IPR001125|InterPro:IPR002048|InterPro:IPR011992 VSTM2L IntAct UniProtKB {GO:0005515=PMID:16713569} Q96N03 V-set and transmembrane domain-containing protein 2-like protein protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:P54253 VSTM4 UniProtKB UniProtKB {GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q8IW00 V-set and transmembrane domain-containing protein 4 protein 20130413 {GO:0005886=IEA, GO:0016021=IEA} integral to membrane, plasma membrane Human UniProtKB-SubCell:SL-0039 VSX2 HPA UniProtKB {GO:0043565=GO_REF:0000002, GO:0008284=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0045165=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0060040=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0007601=GO_REF:0000037, GO:0050896=GO_REF:0000037, GO:0006351=GO_REF:0000037} P58304 Visual system homeobox 2 protein 20080205 {GO:0043565=IEA, GO:0008284=IEA, GO:0005737=IEA, GO:0045165=IEA, GO:0008285=IEA, GO:0003700=IEA, GO:0060040=IEA, GO:0045944=IEA, GO:0005730=IDA, GO:0007601=IEA, GO:0050896=IEA, GO:0006351=IEA} cell fate commitment, negative regulation of cell proliferation, positive regulation of cell proliferation, positive regulation of transcription from RNA polymerase II promoter, response to stimulus, retinal bipolar neuron differentiation, transcription, DNA-dependent, visual perception cytoplasm, nucleolus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human VTA1 Reactome UniProtKB {GO:0005515=PMID:19129479, GO:0016197=Reactome:REACT_27258, GO:0015031=GO_REF:0000037, GO:0016044=Reactome:REACT_11123, GO:0010008=GO_REF:0000039, GO:0005829=Reactome:REACT_27184} Q9NP79 Vacuolar protein sorting-associated protein VTA1 homolog protein 20100729 {GO:0005515=IPI, GO:0016197=TAS, GO:0015031=IEA, GO:0016044=TAS, GO:0010008=IEA, GO:0005829=TAS} cellular membrane organization, endosomal transport, protein transport cytosol, endosome membrane protein binding Human VTCN1 ENSEMBL UniProtKB {GO:0072643=GO_REF:0000019, GO:0050868=GO_REF:0000019, GO:0001562=GO_REF:0000019, GO:0005102=GO_REF:0000019, GO:0072602=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0009897=GO_REF:0000019} Q7Z7D3 V-set domain-containing T-cell activation inhibitor 1 protein 20130413 {GO:0072643=IEA, GO:0050868=IEA, GO:0001562=IEA, GO:0005102=IEA, GO:0072602=IEA, GO:0016021=IEA, GO:0009897=IEA} interferon-gamma secretion, interleukin-4 secretion, negative regulation of T cell activation, response to protozoan external side of plasma membrane, integral to membrane receptor binding Human Ensembl:ENSMUSP00000057721 VTI1A HGNC UniProtKB {GO:0005484=PMID:15215310, GO:0005794=PMID:19224922, GO:0000139=GO_REF:0000039, GO:0031201=PMID:15215310, GO:0042147=PMID:15215310, GO:0016023=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0006886=GO_REF:0000002} Q96AJ9 Vesicle transport through interaction with t-SNAREs homolog 1A protein 20071018 {GO:0005484=IDA, GO:0005794=IDA, GO:0000139=IEA, GO:0031201=TAS, GO:0042147=IDA, GO:0016023=IEA, GO:0016021=IEA, GO:0006886=IEA} intracellular protein transport, retrograde transport, endosome to Golgi Golgi apparatus, Golgi membrane, SNARE complex, cytoplasmic membrane-bounded vesicle, integral to membrane SNAP receptor activity Human VTI1B PINC UniProtKB {GO:0000046=PMID:23217709, GO:0005794=PMID:19224922, GO:0006944=PMID:9446565, GO:0008283=PMID:9446565, GO:0031902=PMID:23217709, GO:0016021=GO_REF:0000037, GO:0016192=PMID:9446565, GO:0005765=PMID:23217709, GO:0006886=GO_REF:0000002, GO:0006904=PMID:9446565, GO:0012505=GO_REF:0000039} Q9UEU0 Vesicle transport through interaction with t-SNAREs homolog 1B protein 20030904 {GO:0000046=IMP, GO:0005794=IDA, GO:0006944=TAS, GO:0008283=TAS, GO:0031902=IDA, GO:0016021=IEA, GO:0016192=TAS, GO:0005765=IDA, GO:0006886=IEA, GO:0006904=TAS, GO:0012505=IEA} autophagic vacuole fusion, cell proliferation, cellular membrane fusion, intracellular protein transport, vesicle docking involved in exocytosis, vesicle-mediated transport Golgi apparatus, endomembrane system, integral to membrane, late endosome membrane, lysosomal membrane Human VTN BHF-UCL UniProtKB {GO:0005515=PMID:8900153, GO:0030949=PMID:19267251, GO:0033627=PMID:8837777, GO:0090303=PMID:8837777, GO:0050731=PMID:10022831, GO:0005576=Reactome:REACT_150335, GO:0005615=PMID:1695900, GO:0014911=PMID:8837777, GO:0032092=PMID:1695900, GO:0031012=PMID:22261194, GO:0010951=PMID:1695900, GO:0061302=PMID:8837777, GO:0006955=GO_REF:0000002, GO:0005178=PMID:8837777, GO:0007160=PMID:10022831, GO:0030198=Reactome:REACT_118779, GO:0030195=PMID:1695900, GO:0048260=PMID:8626514, GO:0071062=PMID:19267251, GO:0030247=GO_REF:0000002, GO:0007155=PMID:2418831, GO:0008201=GO_REF:0000037, GO:0005044=GO_REF:0000002} P04004 Vitronectin protein 20100319 {GO:0005515=IPI, GO:0030949=TAS, GO:0033627=IDA, GO:0090303=IC, GO:0050731=IDA, GO:0005576=TAS, GO:0005615=IDA, GO:0014911=IDA, GO:0032092=IDA, GO:0031012=ISS, GO:0010951=IDA, GO:0061302=IDA, GO:0006955=IEA, GO:0005178=IPI, GO:0007160=IDA, GO:0030198=TAS, GO:0030195=IC, GO:0048260=IDA, GO:0071062=TAS, GO:0030247=IEA, GO:0007155=TAS, GO:0008201=IEA, GO:0005044=IEA} cell adhesion, cell adhesion mediated by integrin, cell-matrix adhesion, extracellular matrix organization, immune response, negative regulation of blood coagulation, negative regulation of endopeptidase activity, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of protein binding, positive regulation of receptor-mediated endocytosis, positive regulation of smooth muscle cell migration, positive regulation of vascular endothelial growth factor receptor signaling pathway, positive regulation of wound healing, smooth muscle cell-matrix adhesion alphav-beta3 integrin-vitronectin complex, extracellular matrix, extracellular region, extracellular space heparin binding, integrin binding, polysaccharide binding, protein binding, scavenger receptor activity Human VWA1 UniProtKB UniProtKB {GO:0030198=GO_REF:0000019, GO:0005614=GO_REF:0000019, GO:0048266=GO_REF:0000019, GO:0042802=GO_REF:0000019, GO:0005604=GO_REF:0000039} Q6PCB0 von Willebrand factor A domain-containing protein 1 protein 20130413 {GO:0030198=IEA, GO:0005614=IEA, GO:0048266=IEA, GO:0042802=IEA, GO:0005604=IEA} behavioral response to pain, extracellular matrix organization basement membrane, interstitial matrix identical protein binding Human UniProtKB-SubCell:SL-0025 VWA2 ENSEMBL UniProtKB {GO:0007161=GO_REF:0000019, GO:0042802=GO_REF:0000019, GO:0005604=GO_REF:0000019} Q5GFL6 von Willebrand factor A domain-containing protein 2 protein 20130413 {GO:0007161=IEA, GO:0042802=IEA, GO:0005604=IEA} calcium-independent cell-matrix adhesion basement membrane identical protein binding Human Ensembl:ENSMUSP00000026068 VWA5A HPA UniProtKB {GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} O00534 von Willebrand factor A domain-containing protein 5A protein 20110516 {GO:0005730=IDA, GO:0005634=IDA} nucleolus, nucleus NOT Human VWA5B2 null null {} null null null null {} null null null VWF IntAct UniProtKB {GO:0005515=PMID:16221672, GO:0005783=PMID:6754744, GO:0005518=PMID:2056120, GO:0051087=PMID:10887119, GO:0002020=PMID:15824096, GO:0042803=PMID:10887119, GO:0001948=PMID:16409464, GO:0019865=PMID:3121636, GO:0031091=PMID:9759493, GO:0031093=Reactome:REACT_21351, GO:0051260=PMID:8874190, GO:0007155=PMID:10764791, GO:0033093=PMID:3087627, GO:0031589=PMID:9079671, GO:0005578=GO_REF:0000039, GO:0009611=PMID:15029268, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_24010, GO:0001890=GO_REF:0000019, GO:0007599=PMID:10887119, GO:0001889=GO_REF:0000019, GO:0031012=PMID:6754744, GO:0047485=PMID:7721887, GO:0005178=PMID:9079671, GO:0007596=Reactome:REACT_2051, GO:0007597=Reactome:REACT_326, GO:0002576=Reactome:REACT_318, GO:0009897=GO_REF:0000019} P04275 von Willebrand factor protein 20130415 {GO:0005515=IPI, GO:0005783=IDA, GO:0005518=IDA, GO:0051087=IDA, GO:0002020=IDA, GO:0042803=IDA, GO:0001948=IDA, GO:0019865=IDA, GO:0031091=NAS, GO:0031093=TAS, GO:0051260=IDA, GO:0007155=IDA, GO:0033093=IDA, GO:0031589=IDA, GO:0005578=IEA, GO:0009611=TAS, GO:0030168=TAS, GO:0005576=TAS, GO:0001890=IEA, GO:0007599=IMP, GO:0001889=IEA, GO:0031012=IDA, GO:0047485=IPI, GO:0005178=IPI, GO:0007596=TAS, GO:0007597=TAS, GO:0002576=TAS, GO:0009897=IEA} blood coagulation, blood coagulation, intrinsic pathway, cell adhesion, cell-substrate adhesion, hemostasis, liver development, placenta development, platelet activation, platelet degranulation, protein homooligomerization, response to wounding Weibel-Palade body, endoplasmic reticulum, external side of plasma membrane, extracellular matrix, extracellular region, platelet alpha granule, platelet alpha granule lumen, proteinaceous extracellular matrix chaperone binding, collagen binding, glycoprotein binding, immunoglobulin binding, integrin binding, protease binding, protein N-terminus binding, protein binding, protein homodimerization activity Human UniProtKB:Q76LX8 WAC BHF-UCL UniProtKB {GO:0005515=PMID:21329877, GO:0000993=PMID:21329877, GO:0005634=PMID:22354037, GO:0032435=PMID:22354037, GO:0006351=GO_REF:0000037, GO:0006974=PMID:21329877, GO:0016607=GO_REF:0000039, GO:0003682=PMID:21329877, GO:0000075=PMID:21329877, GO:0071894=PMID:21329877, GO:0005681=GO_REF:0000019, GO:0045893=PMID:21329877, GO:0010390=PMID:21329877, GO:0016239=PMID:22354037} Q9BTA9 WW domain-containing adapter protein with coiled-coil protein 20120531 {GO:0005515=IPI, GO:0000993=IDA, GO:0005634=TAS, GO:0032435=IMP, GO:0006351=IEA, GO:0006974=IMP, GO:0016607=IEA, GO:0003682=IDA, GO:0000075=IMP, GO:0071894=IMP, GO:0005681=IEA, GO:0045893=IMP, GO:0010390=IMP, GO:0016239=IMP} cell cycle checkpoint, histone H2B conserved C-terminal lysine ubiquitination, histone monoubiquitination, negative regulation of proteasomal ubiquitin-dependent protein catabolic process, positive regulation of macroautophagy, positive regulation of transcription, DNA-dependent, response to DNA damage stimulus, transcription, DNA-dependent nuclear speck, nucleus, spliceosomal complex RNA polymerase II core binding, chromatin binding, protein binding Human WAPAL HPA UniProtKB {GO:0005515=PMID:21111234, GO:0000236=Reactome:REACT_682, GO:0005634=GO_REF:0000052, GO:0071922=PMID:17113138, GO:0035562=PMID:17113138, GO:0045875=PMID:19696148, GO:0043231=GO_REF:0000052, GO:0005829=Reactome:REACT_150294, GO:0000084=Reactome:REACT_899, GO:0000910=Reactome:REACT_1932, GO:0005737=PMID:17113138, GO:0000087=Reactome:REACT_910, GO:0015630=GO_REF:0000052, GO:0000785=PMID:19696148, GO:0000795=GO_REF:0000019, GO:0005694=Reactome:REACT_150454, GO:0005730=GO_REF:0000052, GO:0009636=GO_REF:0000019, GO:0008278=PMID:19696148, GO:0019048=GO_REF:0000037, GO:0005654=Reactome:REACT_150456, GO:0008156=PMID:19907496, GO:0071168=PMID:21111234, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0000775=Reactome:REACT_150445} Q8WVX6 Wings apart-like protein homolog protein 20111111 {GO:0005515=IPI, GO:0000236=TAS, GO:0005634=IDA, GO:0071922=IMP, GO:0035562=IMP, GO:0045875=IMP, GO:0043231=IDA, GO:0005829=TAS, GO:0000084=TAS, GO:0000910=TAS, GO:0005737=IDA, GO:0000087=TAS, GO:0015630=IDA, GO:0000785=IDA, GO:0000795=IEA, GO:0005694=TAS, GO:0005730=IDA, GO:0009636=IEA, GO:0008278=IDA, GO:0019048=IEA, GO:0005654=TAS, GO:0008156=IMP, GO:0071168=IMP, GO:0000278=TAS, GO:0000090=TAS, GO:0000775=TAS} M phase of mitotic cell cycle, S phase of mitotic cell cycle, cytokinesis, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, negative regulation of DNA replication, negative regulation of chromatin binding, negative regulation of sister chromatid cohesion, protein localization to chromatin, regulation of cohesin localization to chromatin, response to toxic substance, virus-host interaction chromatin, chromosome, chromosome, centromeric region, cohesin complex, cytoplasm, cytosol, intracellular membrane-bounded organelle, microtubule cytoskeleton, nucleolus, nucleoplasm, nucleus, synaptonemal complex protein binding Human WARS UniProtKB UniProtKB {GO:0005515=PMID:15628863, GO:0010467=Reactome:REACT_71, GO:0008285=PMID:1761529, GO:0045765=PMID:11773626, GO:0001525=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0006412=PMID:1761529, GO:0004812=GO_REF:0000038, GO:0006418=Reactome:REACT_15482, GO:0005829=Reactome:REACT_15412, GO:0006436=PMID:8496617, GO:0004830=Reactome:REACT_15412, GO:0005737=PMID:16130169} P78534 Tryptophanyl-tRNA synthetase protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0008285=TAS, GO:0045765=IDA, GO:0001525=IEA, GO:0005524=IEA, GO:0006412=TAS, GO:0004812=IEA, GO:0006418=TAS, GO:0005829=TAS, GO:0006436=NAS, GO:0004830=TAS, GO:0005737=TAS} angiogenesis, gene expression, negative regulation of cell proliferation, regulation of angiogenesis, tRNA aminoacylation for protein translation, translation, tryptophanyl-tRNA aminoacylation cytoplasm, cytosol ATP binding, aminoacyl-tRNA ligase activity, protein binding, tryptophan-tRNA ligase activity Human UniProtKB-KW:KW-0030 WARS2 Reactome UniProtKB {GO:0005739=GO_REF:0000019, GO:0006436=GO_REF:0000002, GO:0010467=Reactome:REACT_71, GO:0004830=GO_REF:0000003, GO:0005759=Reactome:REACT_15343, GO:0001570=GO_REF:0000019, GO:0005524=GO_REF:0000037, GO:0006418=Reactome:REACT_15482} Q9UGM6 Tryptophan--tRNA ligase, mitochondrial protein 20130301 {GO:0005739=IEA, GO:0006436=IEA, GO:0010467=TAS, GO:0004830=IEA, GO:0005759=TAS, GO:0001570=IEA, GO:0005524=IEA, GO:0006418=TAS} gene expression, tRNA aminoacylation for protein translation, tryptophanyl-tRNA aminoacylation, vasculogenesis mitochondrial matrix, mitochondrion ATP binding, tryptophan-tRNA ligase activity Human WAS IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0012506=GO_REF:0000019, GO:0030048=GO_REF:0000019, GO:0050852=Reactome:REACT_12526, GO:0003779=GO_REF:0000002, GO:0006952=PMID:8069912, GO:0015629=GO_REF:0000002, GO:0005829=Reactome:REACT_160291, GO:0042802=PMID:12769847, GO:0042110=GO_REF:0000019, GO:0005083=GO_REF:0000002, GO:0006955=PMID:8069912, GO:0006461=PMID:8625410, GO:0008544=PMID:8069912, GO:0008154=PMID:8625410, GO:0007596=PMID:8069912, GO:0045087=Reactome:REACT_6802, GO:0016197=GO_REF:0000019, GO:0030041=GO_REF:0000019, GO:0038096=Reactome:REACT_160123} P42768 Wiskott-Aldrich syndrome protein protein 20130415 {GO:0005515=IPI, GO:0012506=IEA, GO:0030048=IEA, GO:0050852=TAS, GO:0003779=IEA, GO:0006952=TAS, GO:0015629=IEA, GO:0005829=TAS, GO:0042802=IPI, GO:0042110=IEA, GO:0005083=IEA, GO:0006955=IMP, GO:0006461=TAS, GO:0008544=TAS, GO:0008154=TAS, GO:0007596=TAS, GO:0045087=TAS, GO:0016197=IEA, GO:0030041=IEA, GO:0038096=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, T cell activation, T cell receptor signaling pathway, actin filament polymerization, actin filament-based movement, actin polymerization or depolymerization, blood coagulation, defense response, endosomal transport, epidermis development, immune response, innate immune response, protein complex assembly actin cytoskeleton, cytosol, vesicle membrane actin binding, identical protein binding, protein binding, small GTPase regulator activity Human UniProtKB:P42768 WASF1 IntAct UniProtKB {GO:0005515=PMID:9843499, GO:0006461=PMID:10381382, GO:0030041=PMID:9843499, GO:0006928=PMID:2775266, GO:0003779=GO_REF:0000037, GO:0005741=GO_REF:0000019, GO:0015629=PMID:9843499, GO:0005856=PMID:10970852, GO:0030027=GO_REF:0000019} Q92558 Wiskott-Aldrich syndrome protein family member 1 protein 20130415 {GO:0005515=IPI, GO:0006461=NAS, GO:0030041=TAS, GO:0006928=TAS, GO:0003779=IEA, GO:0005741=IEA, GO:0015629=TAS, GO:0005856=TAS, GO:0030027=IEA} actin filament polymerization, cellular component movement, protein complex assembly actin cytoskeleton, cytoskeleton, lamellipodium, mitochondrial outer membrane actin binding, protein binding Human UniProtKB:P07737 WASF2 IntAct UniProtKB {GO:0030048=GO_REF:0000019, GO:0005515=PMID:11130076, GO:0030036=GO_REF:0000019, GO:0001667=GO_REF:0000019, GO:0030032=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0001525=GO_REF:0000019, GO:0015629=PMID:10970852, GO:0001726=GO_REF:0000019, GO:0030027=PMID:17101133, GO:0005829=Reactome:REACT_160291, GO:0005622=PMID:17101133, GO:0016601=GO_REF:0000019, GO:0045087=Reactome:REACT_6802, GO:0007188=PMID:9732292, GO:0038096=Reactome:REACT_160123, GO:0005769=GO_REF:0000019} Q9Y6W5 Wiskott-Aldrich syndrome protein family member 2 protein 20130415 {GO:0030048=IEA, GO:0005515=IPI, GO:0030036=IEA, GO:0001667=IEA, GO:0030032=IEA, GO:0003779=IEA, GO:0001525=IEA, GO:0015629=TAS, GO:0001726=IEA, GO:0030027=IDA, GO:0005829=TAS, GO:0005622=IDA, GO:0016601=IEA, GO:0045087=TAS, GO:0007188=TAS, GO:0038096=TAS, GO:0005769=IEA} Fc-gamma receptor signaling pathway involved in phagocytosis, Rac protein signal transduction, actin cytoskeleton organization, actin filament-based movement, adenylate cyclase-modulating G-protein coupled receptor signaling pathway, ameboidal cell migration, angiogenesis, innate immune response, lamellipodium assembly actin cytoskeleton, cytosol, early endosome, intracellular, lamellipodium, ruffle actin binding, protein binding Human UniProtKB:Q9UQB8-4 WASF3 PINC UniProtKB {GO:0005737=GO_REF:0000037, GO:0006461=PMID:10381382, GO:0008360=PMID:21834987, GO:0014003=GO_REF:0000019, GO:0007010=PMID:21834987, GO:0030032=GO_REF:0000019, GO:0030041=PMID:10381382, GO:0003779=GO_REF:0000037, GO:0005856=GO_REF:0000039, GO:0030027=GO_REF:0000019, GO:0031643=GO_REF:0000019} Q9UPY6 Wiskott-Aldrich syndrome protein family member 3 protein 20040308 {GO:0005737=IEA, GO:0006461=TAS, GO:0008360=IMP, GO:0014003=IEA, GO:0007010=IMP, GO:0030032=IEA, GO:0030041=TAS, GO:0003779=IEA, GO:0005856=IEA, GO:0030027=IEA, GO:0031643=IEA} actin filament polymerization, cytoskeleton organization, lamellipodium assembly, oligodendrocyte development, positive regulation of myelination, protein complex assembly, regulation of cell shape cytoplasm, cytoskeleton, lamellipodium actin binding Human WASH1 UniProtKB UniProtKB {GO:0005515=PMID:19922874, GO:0034314=GO_REF:0000024, GO:0043014=PMID:19922874, GO:0031901=GO_REF:0000039, GO:0016197=GO_REF:0000024, GO:0071203=PMID:19922875, GO:0042147=PMID:19922874, GO:0003779=GO_REF:0000037, GO:0055037=GO_REF:0000024, GO:0055038=GO_REF:0000039, GO:0005769=PMID:19922874} A8K0Z3 WAS protein family homolog 1 protein 20091127 {GO:0005515=IPI, GO:0034314=ISS, GO:0043014=IDA, GO:0031901=IEA, GO:0016197=ISS, GO:0071203=IDA, GO:0042147=IMP, GO:0003779=IEA, GO:0055037=ISS, GO:0055038=IEA, GO:0005769=IDA} Arp2/3 complex-mediated actin nucleation, endosomal transport, retrograde transport, endosome to Golgi WASH complex, early endosome, early endosome membrane, recycling endosome, recycling endosome membrane actin binding, alpha-tubulin binding, protein binding Human UniProtKB:Q9Y4E1 WASL BHF-UCL UniProtKB {GO:0005515=PMID:21706016, GO:2000370=GO_REF:0000024, GO:0005886=Reactome:REACT_22183, GO:0050999=Reactome:REACT_12541, GO:0051491=GO_REF:0000024, GO:0006928=PMID:9422512, GO:0005634=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:0006900=GO_REF:0000024, GO:0015629=PMID:9422512, GO:0005829=Reactome:REACT_160291, GO:0016050=GO_REF:0000024, GO:0009617=GO_REF:0000019, GO:0005083=GO_REF:0000002, GO:0007411=Reactome:REACT_18266, GO:0034629=GO_REF:0000019, GO:0046209=Reactome:REACT_12508, GO:0006355=GO_REF:0000037, GO:0030478=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0030027=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0051653=GO_REF:0000019, GO:0030666=Reactome:REACT_12634, GO:0006461=GO_REF:0000002, GO:0008154=GO_REF:0000002, GO:0045087=Reactome:REACT_6802, GO:0030050=GO_REF:0000024, GO:0016023=GO_REF:0000024, GO:0038096=Reactome:REACT_160123} O00401 Neural Wiskott-Aldrich syndrome protein protein 20120517 {GO:0005515=IPI, GO:2000370=ISS, GO:0005886=TAS, GO:0050999=TAS, GO:0051491=ISS, GO:0006928=TAS, GO:0005634=IEA, GO:0044281=TAS, GO:0006900=ISS, GO:0015629=TAS, GO:0005829=TAS, GO:0016050=ISS, GO:0009617=IEA, GO:0005083=IEA, GO:0007411=TAS, GO:0034629=IEA, GO:0046209=TAS, GO:0006355=IEA, GO:0030478=IEA, GO:0003779=IEA, GO:0030027=IEA, GO:0006351=IEA, GO:0051653=IEA, GO:0030666=TAS, GO:0006461=IEA, GO:0008154=IEA, GO:0045087=TAS, GO:0030050=ISS, GO:0016023=ISS, GO:0038096=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, actin polymerization or depolymerization, axon guidance, cellular component movement, cellular protein complex localization, innate immune response, membrane budding, nitric oxide metabolic process, positive regulation of clathrin-mediated endocytosis, positive regulation of filopodium assembly, protein complex assembly, regulation of nitric-oxide synthase activity, regulation of transcription, DNA-dependent, response to bacterium, small molecule metabolic process, spindle localization, transcription, DNA-dependent, vesicle organization, vesicle transport along actin filament actin cap, actin cytoskeleton, cytoplasmic membrane-bounded vesicle, cytosol, endocytic vesicle membrane, lamellipodium, nucleus, plasma membrane actin binding, protein binding, small GTPase regulator activity Human UniProtKB:O08816 WBP1 IntAct UniProtKB {GO:0005515=PMID:15064722, GO:0008150=GO_REF:0000015, GO:0050699=PMID:15064722, GO:0005575=GO_REF:0000015} Q96G27 WW domain-binding protein 1 protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0050699=IPI, GO:0005575=ND} biological_process cellular_component WW domain binding, protein binding Human UniProtKB:Q9NZC7 WBP11 IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0006397=GO_REF:0000037, GO:0008599=GO_REF:0000019, GO:0008380=GO_REF:0000019, GO:0006396=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0003697=PMID:10593949, GO:0016607=GO_REF:0000019, GO:0050699=PMID:19592703, GO:0006364=GO_REF:0000037, GO:0005634=PMID:10593949} Q9Y2W2 WW domain-binding protein 11 protein 20130415 {GO:0005515=IPI, GO:0006397=IEA, GO:0008599=IEA, GO:0008380=IEA, GO:0006396=IEA, GO:0005737=IEA, GO:0003697=TAS, GO:0016607=IEA, GO:0050699=IPI, GO:0006364=IEA, GO:0005634=TAS} RNA processing, RNA splicing, mRNA processing, rRNA processing cytoplasm, nuclear speck, nucleus WW domain binding, protein binding, protein phosphatase type 1 regulator activity, single-stranded DNA binding Human UniProtKB:Q15365 WBP2 IntAct UniProtKB {GO:0005515=PMID:20972459, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q969T9 WW domain-binding protein 2 protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component protein binding Human UniProtKB:Q9GZV5 WBP4 HPA UniProtKB {GO:0005886=GO_REF:0000052, GO:0016607=PMID:19592703, GO:0045292=PMID:19592703, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005681=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0070064=PMID:19592703} O75554 WW domain-binding protein 4 protein 20110516 {GO:0005886=IDA, GO:0016607=IDA, GO:0045292=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0005681=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0070064=IPI} mRNA cis splicing, via spliceosome nuclear speck, nucleolus, nucleus, plasma membrane, spliceosomal complex nucleic acid binding, proline-rich region binding, zinc ion binding Human WBP5 ENSEMBL UniProtKB {GO:0050699=GO_REF:0000019} Q9UHQ7 WW domain-binding protein 5 protein 20130413 {GO:0050699=IEA} WW domain binding Human Ensembl:ENSMUSP00000047474 WBSCR16 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q96I51 Williams-Beuren syndrome chromosomal region 16 protein protein 20061026 {GO:0005739=IEA, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component, mitochondrion Human WBSCR22 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0008168=PMID:11124703, GO:0005634=GO_REF:0000039, GO:0005575=GO_REF:0000015} O43709 Uncharacterized methyltransferase WBSCR22 protein 20061026 {GO:0008150=ND, GO:0008168=NAS, GO:0005634=IEA, GO:0005575=ND} biological_process cellular_component, nucleus methyltransferase activity Human WBSCR27 null null {} null null null null {} null null null WDFY1 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0005545=PMID:11739631, GO:0005634=PMID:11739631, GO:0008270=PMID:11739631, GO:0005769=PMID:11739631, GO:0005829=PMID:11739631} Q8IWB7 WD repeat and FYVE domain-containing protein 1 protein 20061026 {GO:0008150=ND, GO:0005545=IDA, GO:0005634=IDA, GO:0008270=NAS, GO:0005769=IDA, GO:0005829=IDA} biological_process cytosol, early endosome, nucleus 1-phosphatidylinositol binding, zinc ion binding Human WDFY3 IntAct UniProtKB {GO:0005515=PMID:20417604, GO:0044444=PMID:15292400, GO:0005545=PMID:15292400, GO:0005737=GO_REF:0000019, GO:0005776=PMID:15292400, GO:0003831=GO_REF:0000019, GO:0005635=PMID:15292400, GO:0046872=GO_REF:0000037, GO:0019898=PMID:15292400} Q8IZQ1 WD repeat and FYVE domain-containing protein 3 protein 20130415 {GO:0005515=IPI, GO:0044444=IDA, GO:0005545=IDA, GO:0005737=IEA, GO:0005776=IDA, GO:0003831=IEA, GO:0005635=IDA, GO:0046872=IEA, GO:0019898=IDA} autophagic vacuole, cytoplasm, cytoplasmic part, extrinsic to membrane, nuclear envelope 1-phosphatidylinositol binding, beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity, metal ion binding, protein binding Human UniProtKB:Q9H1Y0 WDFY4 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q6ZS81 WD repeat- and FYVE domain-containing protein 4 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 WDHD1 HPA UniProtKB {GO:0005515=PMID:21725360, GO:0006396=GO_REF:0000019, GO:0070829=GO_REF:0000019, GO:0003723=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0005737=PMID:9175701, GO:0003682=GO_REF:0000019, GO:0005654=GO_REF:0000039, GO:0070063=GO_REF:0000019, GO:0000775=GO_REF:0000019, GO:0033044=GO_REF:0000019} O75717 WD repeat and HMG-box DNA-binding protein 1 protein 20080205 {GO:0005515=IPI, GO:0006396=IEA, GO:0070829=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0005737=TAS, GO:0003682=IEA, GO:0005654=IEA, GO:0070063=IEA, GO:0000775=IEA, GO:0033044=IEA} RNA processing, heterochromatin maintenance, regulation of chromosome organization chromosome, centromeric region, cytoplasm, nucleolus, nucleoplasm, nucleus DNA binding, RNA binding, RNA polymerase binding, chromatin binding, protein binding NOT Human WDR1 Reactome UniProtKB {GO:0007596=Reactome:REACT_604, GO:0007605=PMID:10036186, GO:0002576=Reactome:REACT_318, GO:0030168=Reactome:REACT_798, GO:0005576=Reactome:REACT_21347, GO:0003779=GO_REF:0000037, GO:0005856=GO_REF:0000039, GO:0005829=Reactome:REACT_21347} O75083 WD repeat-containing protein 1 protein 20130301 {GO:0007596=TAS, GO:0007605=TAS, GO:0002576=TAS, GO:0030168=TAS, GO:0005576=TAS, GO:0003779=IEA, GO:0005856=IEA, GO:0005829=TAS} blood coagulation, platelet activation, platelet degranulation, sensory perception of sound cytoskeleton, cytosol, extracellular region actin binding Human WDR11 MGI UniProtKB {GO:0005515=PMID:20887964, GO:0005929=GO_REF:0000019, GO:0005737=PMID:20887964, GO:0005634=GO_REF:0000039, GO:0016021=GO_REF:0000037} Q9BZH6 WD repeat-containing protein 11 protein 20120406 {GO:0005515=IPI, GO:0005929=IEA, GO:0005737=IDA, GO:0005634=IEA, GO:0016021=IEA} cilium, cytoplasm, integral to membrane, nucleus protein binding Human WDR12 IntAct UniProtKB {GO:0070545=PMID:16738141, GO:0005515=PMID:16043514, GO:0000463=PMID:17353269, GO:0007219=GO_REF:0000019, GO:0008283=PMID:16043514, GO:0005730=PMID:16043514, GO:0042273=PMID:17353269, GO:0005654=PMID:16043514, GO:0030687=PMID:17353269, GO:0000466=PMID:16043514} Q9GZL7 Ribosome biogenesis protein WDR12 protein 20130415 {GO:0070545=IDA, GO:0005515=IPI, GO:0000463=IMP, GO:0007219=IEA, GO:0008283=IMP, GO:0005730=IDA, GO:0042273=IC, GO:0005654=IDA, GO:0030687=IDA, GO:0000466=IMP} Notch signaling pathway, cell proliferation, maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), ribosomal large subunit biogenesis PeBoW complex, nucleolus, nucleoplasm, preribosome, large subunit precursor protein binding Human UniProtKB:Q14137 WDR13 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9H1Z4 WD repeat-containing protein 13 protein 20080818 {GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA} cytoplasm, nucleolus, nucleus Human WDR16 HPA UniProtKB {GO:0005515=PMID:15967112, GO:0005737=GO_REF:0000052, GO:0043231=GO_REF:0000052} Q8N1V2 WD repeat-containing protein 16 protein 20101115 {GO:0005515=IPI, GO:0005737=IDA, GO:0043231=IDA} cytoplasm, intracellular membrane-bounded organelle protein binding Human WDR17 null null {} null null null null {} null null null WDR18 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005654=GO_REF:0000039, GO:0007275=GO_REF:0000037} Q9BV38 WD repeat-containing protein 18 protein 20130413 {GO:0005737=IEA, GO:0005654=IEA, GO:0007275=IEA} multicellular organismal development cytoplasm, nucleoplasm Human UniProtKB-SubCell:SL-0086 WDR19 UniProtKB UniProtKB {GO:0055123=GO_REF:0000019, GO:0042471=GO_REF:0000019, GO:0031514=GO_REF:0000024, GO:0060830=GO_REF:0000019, GO:0031513=GO_REF:0000024, GO:0030326=GO_REF:0000019, GO:0060831=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0048701=GO_REF:0000019, GO:0061055=GO_REF:0000019, GO:0042384=GO_REF:0000019, GO:0005737=GO_REF:0000037, GO:0031076=GO_REF:0000019, GO:0030991=PMID:20889716, GO:0032391=GO_REF:0000024, GO:0050877=GO_REF:0000019, GO:0005932=GO_REF:0000039} Q8NEZ3 WD repeat-containing protein 19 protein 20130222 {GO:0055123=IEA, GO:0042471=IEA, GO:0031514=ISS, GO:0060830=IEA, GO:0031513=ISS, GO:0030326=IEA, GO:0060831=IEA, GO:0001701=IEA, GO:0048701=IEA, GO:0061055=IEA, GO:0042384=IEA, GO:0005737=IEA, GO:0031076=IEA, GO:0030991=IDA, GO:0032391=ISS, GO:0050877=IEA, GO:0005932=IEA} ciliary receptor clustering involved in smoothened signaling pathway, cilium assembly, digestive system development, ear morphogenesis, embryonic camera-type eye development, embryonic cranial skeleton morphogenesis, embryonic limb morphogenesis, in utero embryonic development, myotome development, neurological system process, smoothened signaling pathway involved in dorsal/ventral neural tube patterning cytoplasm, intraflagellar transport particle A, microtubule basal body, motile cilium, nonmotile primary cilium, photoreceptor connecting cilium Human WDR20 null null {} null null null null {} null null null WDR24 InterPro UniProtKB {GO:0005053=GO_REF:0000002, GO:0016558=GO_REF:0000002, GO:0005777=GO_REF:0000002} Q96S15 WD repeat-containing protein 24 protein 20130413 {GO:0005053=IEA, GO:0016558=IEA, GO:0005777=IEA} protein import into peroxisome matrix peroxisome peroxisome matrix targeting signal-2 binding Human InterPro:IPR025651 WDR25 null null {} null null null null {} null null null WDR26 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9H7D7 WD repeat-containing protein 26 protein 20101115 {GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA} cytoplasm, nucleolus, nucleus Human WDR3 HPA UniProtKB {GO:0031965=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q9UNX4 WD repeat-containing protein 3 protein 20101115 {GO:0031965=IDA, GO:0005730=IDA, GO:0005634=IDA} nuclear membrane, nucleolus, nucleus Human WDR33 HPA UniProtKB {GO:0006397=GO_REF:0000037, GO:0005581=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0007283=PMID:11162572, GO:0006301=PMID:11162572} Q9C0J8 pre-mRNA 3' end processing protein WDR33 protein 20111111 {GO:0006397=IEA, GO:0005581=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0007283=NAS, GO:0006301=NAS} mRNA processing, postreplication repair, spermatogenesis collagen, nucleolus, nucleus NOT Human WDR34 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039} Q96EX3 WD repeat-containing protein 34 protein 20130413 {GO:0005737=IEA} cytoplasm Human UniProtKB-SubCell:SL-0086 WDR35 UniProtKB UniProtKB {GO:0042384=PMID:21473986, GO:0005813=GO_REF:0000024, GO:0030991=PMID:20889716, GO:0005932=GO_REF:0000024, GO:0035085=GO_REF:0000024} Q9P2L0 WD repeat-containing protein 35 protein 20130222 {GO:0042384=IMP, GO:0005813=ISS, GO:0030991=IDA, GO:0005932=ISS, GO:0035085=ISS} cilium assembly centrosome, cilium axoneme, intraflagellar transport particle A, microtubule basal body Human WDR36 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0006364=GO_REF:0000002, GO:0032040=GO_REF:0000002, GO:0005730=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0007601=GO_REF:0000037, GO:0050896=GO_REF:0000037} Q8NI36 WD repeat-containing protein 36 protein 20071011 {GO:0003674=ND, GO:0008150=ND, GO:0006364=IEA, GO:0032040=IEA, GO:0005730=IEA, GO:0005575=ND, GO:0007601=IEA, GO:0050896=IEA} biological_process, rRNA processing, response to stimulus, visual perception cellular_component, nucleolus, small-subunit processome molecular_function Human WDR37 null null {} null null null null {} null null null WDR4 GOC UniProtKB {GO:0005515=PMID:15861136, GO:0005737=GO_REF:0000052, GO:0005654=PMID:16780588, GO:0008176=PMID:12403464, GO:0005634=GO_REF:0000052, GO:0006400=PMID:15861136, GO:0036265=PMID:12403464} P57081 tRNA (guanine-N(7)-)-methyltransferase subunit WDR4 protein 20130413 {GO:0005515=IPI, GO:0005737=IDA, GO:0005654=IDA, GO:0008176=IDA, GO:0005634=IDA, GO:0006400=IDA, GO:0036265=IDA} RNA (guanine-N7)-methylation, tRNA modification cytoplasm, nucleoplasm, nucleus protein binding, tRNA (guanine-N7-)-methyltransferase activity Human WDR41 null null {} null null null null {} null null null WDR43 UniProtKB UniProtKB {GO:0005730=GO_REF:0000039} Q15061 WD repeat-containing protein 43 protein 20130413 {GO:0005730=IEA} nucleolus Human UniProtKB-SubCell:SL-0188 WDR44 UniProtKB UniProtKB {GO:0048471=GO_REF:0000039, GO:0005794=GO_REF:0000039, GO:0010008=GO_REF:0000039, GO:0005829=GO_REF:0000039} Q5JSH3 WD repeat-containing protein 44 protein 20130413 {GO:0048471=IEA, GO:0005794=IEA, GO:0010008=IEA, GO:0005829=IEA} Golgi apparatus, cytosol, endosome membrane, perinuclear region of cytoplasm Human UniProtKB-SubCell:SL-0198 WDR45 RefGenome UniProtKB {GO:0005737=GO_REF:0000033, GO:0005083=GO_REF:0000002, GO:0080025=GO_REF:0000033, GO:0032266=GO_REF:0000033, GO:0000045=GO_REF:0000033} Q9Y484 WD repeat domain phosphoinositide-interacting protein 4 protein 20110221 {GO:0005737=IBA, GO:0005083=IEA, GO:0080025=IBA, GO:0032266=IBA, GO:0000045=IBA} autophagic vacuole assembly cytoplasm phosphatidylinositol-3,5-bisphosphate binding, phosphatidylinositol-3-phosphate binding, small GTPase regulator activity Human PANTHER:PTN000132136 WDR46 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} O15213 WD repeat-containing protein 46 protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human WDR47 UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0005874=GO_REF:0000037, GO:0007275=GO_REF:0000037} O94967 WD repeat-containing protein 47 protein 20130413 {GO:0005737=IEA, GO:0005874=IEA, GO:0007275=IEA} multicellular organismal development cytoplasm, microtubule Human UniProtKB-KW:KW-0217 WDR48 HPA UniProtKB {GO:0005515=PMID:19075014, GO:0016579=PMID:18082604, GO:0019048=GO_REF:0000037, GO:0005634=PMID:18082604, GO:0005764=GO_REF:0000039, GO:0043231=GO_REF:0000052} Q8TAF3 WD repeat-containing protein 48 protein 20110516 {GO:0005515=IPI, GO:0016579=IDA, GO:0019048=IEA, GO:0005634=IDA, GO:0005764=IEA, GO:0043231=IDA} protein deubiquitination, virus-host interaction intracellular membrane-bounded organelle, lysosome, nucleus protein binding Human WDR5 BHF-UCL UniProtKB {GO:0005515=PMID:20581860, GO:0006355=GO_REF:0000037, GO:0005634=PMID:17500065, GO:0042800=PMID:17355966, GO:0006351=GO_REF:0000037, GO:0043981=PMID:20018852, GO:0001501=GO_REF:0000019, GO:0035097=PMID:17500065, GO:0043982=PMID:20018852, GO:0043966=PMID:18838386, GO:0043984=PMID:20018852, GO:0048188=PMID:18838538, GO:0043996=PMID:20018852, GO:0071339=PMID:15960975, GO:0043995=PMID:20018852, GO:0000123=PMID:20018852, GO:0005671=PMID:18838386, GO:0046972=PMID:20018852, GO:0051568=PMID:17355966} P61964 WD repeat-containing protein 5 protein 20101105 {GO:0005515=IPI, GO:0006355=IEA, GO:0005634=IDA, GO:0042800=IDA, GO:0006351=IEA, GO:0043981=IDA, GO:0001501=IEA, GO:0035097=IDA, GO:0043982=IDA, GO:0043966=IDA, GO:0043984=IDA, GO:0048188=IDA, GO:0043996=IDA, GO:0071339=IDA, GO:0043995=IDA, GO:0000123=IDA, GO:0005671=IDA, GO:0046972=IDA, GO:0051568=IDA} histone H3 acetylation, histone H3-K4 methylation, histone H4-K16 acetylation, histone H4-K5 acetylation, histone H4-K8 acetylation, regulation of transcription, DNA-dependent, skeletal system development, transcription, DNA-dependent Ada2/Gcn5/Ada3 transcription activator complex, MLL1 complex, Set1C/COMPASS complex, histone acetyltransferase complex, histone methyltransferase complex, nucleus histone acetyltransferase activity (H4-K16 specific), histone acetyltransferase activity (H4-K5 specific), histone acetyltransferase activity (H4-K8 specific), histone methyltransferase activity (H3-K4 specific), protein binding Human WDR53 null null {} null null null null {} null null null WDR54 null null {} null null null null {} null null null WDR55 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000039, GO:0006364=GO_REF:0000024, GO:0005730=GO_REF:0000024, GO:0005575=GO_REF:0000015} Q9H6Y2 WD repeat-containing protein 55 protein 20090422 {GO:0008150=ND, GO:0003674=ND, GO:0005737=IEA, GO:0006364=ISS, GO:0005730=ISS, GO:0005575=ND} biological_process, rRNA processing cellular_component, cytoplasm, nucleolus molecular_function Human UniProtKB:Q9CX97 WDR59 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0005575=GO_REF:0000015} Q6PJI9 WD repeat-containing protein 59 protein 20090401 {GO:0003674=ND, GO:0008150=ND, GO:0005575=ND} biological_process cellular_component molecular_function Human WDR5B null null {} null null null null {} null null null WDR6 HPA UniProtKB {GO:0005515=PMID:17216128, GO:0043234=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0008285=PMID:17216128, GO:0008180=PMID:18850735, GO:0010507=PMID:22354037, GO:0007050=PMID:17216128, GO:0043560=GO_REF:0000019} Q9NNW5 WD repeat-containing protein 6 protein 20111111 {GO:0005515=IPI, GO:0043234=IEA, GO:0005737=IDA, GO:0008285=IDA, GO:0008180=IDA, GO:0010507=IMP, GO:0007050=IDA, GO:0043560=IEA} cell cycle arrest, negative regulation of autophagy, negative regulation of cell proliferation cytoplasm, protein complex, signalosome insulin receptor substrate binding, protein binding Human WDR60 ENSEMBL UniProtKB {GO:0005929=GO_REF:0000019} Q8WVS4 WD repeat-containing protein 60 protein 20130413 {GO:0005929=IEA} cilium Human Ensembl:ENSMUSP00000047334 WDR61 HPA UniProtKB {GO:0005515=PMID:20178742, GO:0080182=PMID:16024656, GO:0005730=GO_REF:0000052, GO:0035327=PMID:16024656, GO:0005634=GO_REF:0000052, GO:0055087=PMID:16024656, GO:0006351=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0051571=PMID:16024656, GO:0045638=PMID:20541477, GO:0045944=PMID:20178742, GO:0032968=PMID:20178742, GO:2001162=PMID:16024656, GO:0016593=PMID:20178742, GO:0016055=GO_REF:0000037} Q9GZS3 WD repeat-containing protein 61 protein 20110516 {GO:0005515=IPI, GO:0080182=IMP, GO:0005730=IDA, GO:0035327=IDA, GO:0005634=IDA, GO:0055087=IDA, GO:0006351=IEA, GO:0005737=IDA, GO:0051571=IMP, GO:0045638=IDA, GO:0045944=IDA, GO:0032968=IDA, GO:2001162=IMP, GO:0016593=IDA, GO:0016055=IEA} Wnt receptor signaling pathway, histone H3-K4 trimethylation, negative regulation of myeloid cell differentiation, positive regulation of histone H3-K4 methylation, positive regulation of histone H3-K79 methylation, positive regulation of transcription elongation from RNA polymerase II promoter, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent Cdc73/Paf1 complex, Ski complex, cytoplasm, nucleolus, nucleus, transcriptionally active chromatin protein binding Human WDR62 UniProtKB UniProtKB {GO:0000922=PMID:20890279, GO:0005737=GO_REF:0000037, GO:0021987=PMID:20729831, GO:0005634=PMID:20729831, GO:0022008=PMID:20890278} O43379 WD repeat-containing protein 62 protein 20110817 {GO:0000922=IDA, GO:0005737=IEA, GO:0021987=IMP, GO:0005634=IDA, GO:0022008=IMP} cerebral cortex development, neurogenesis cytoplasm, nucleus, spindle pole Human WDR65 null null {} null null null null {} null null null WDR66 InterPro UniProtKB {GO:0005509=GO_REF:0000002} Q8TBY9 WD repeat-containing protein 66 protein 20130413 {GO:0005509=IEA} calcium ion binding Human InterPro:IPR011992 WDR67 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0005813=PMID:21399614, GO:0005097=GO_REF:0000002} Q96DN5 WD repeat-containing protein 67 protein 20110517 {GO:0005622=IEA, GO:0005813=IDA, GO:0005097=IEA} centrosome, intracellular Rab GTPase activator activity Human WDR7 null null {} null null null null {} null null null WDR70 null null {} null null null null {} null null null WDR73 null null {} null null null null {} null null null WDR74 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0016070=GO_REF:0000019, GO:0005730=PMID:12429849, GO:0001825=GO_REF:0000019, GO:0005634=GO_REF:0000019} Q6RFH5 WD repeat-containing protein 74 protein 20081126 {GO:0008150=ND, GO:0003674=ND, GO:0016070=IEA, GO:0005730=IDA, GO:0001825=IEA, GO:0005634=IEA} RNA metabolic process, biological_process, blastocyst formation nucleolus, nucleus molecular_function Human WDR75 HPA UniProtKB {GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052} Q8IWA0 WD repeat-containing protein 75 protein 20110516 {GO:0005730=IDA, GO:0005634=IDA} nucleolus, nucleus NOT Human WDR76 null null {} null null null null {} null null null WDR77 HPA UniProtKB {GO:0060770=GO_REF:0000019, GO:0005515=PMID:16087681, GO:0010467=Reactome:REACT_71, GO:0008284=GO_REF:0000019, GO:0005794=GO_REF:0000052, GO:0016070=Reactome:REACT_21257, GO:0006357=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0034660=Reactome:REACT_11052, GO:0000387=Reactome:REACT_11066, GO:0005829=Reactome:REACT_10041, GO:0005737=GO_REF:0000052, GO:0030374=PMID:12972618, GO:0060528=GO_REF:0000019} Q9BQA1 Methylosome protein 50 protein 20111111 {GO:0060770=IEA, GO:0005515=IPI, GO:0010467=TAS, GO:0008284=IEA, GO:0005794=IDA, GO:0016070=TAS, GO:0006357=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0034660=TAS, GO:0000387=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0030374=IGI, GO:0060528=IEA} RNA metabolic process, gene expression, ncRNA metabolic process, negative regulation of epithelial cell proliferation involved in prostate gland development, positive regulation of cell proliferation, regulation of transcription from RNA polymerase II promoter, secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development, spliceosomal snRNP assembly Golgi apparatus, cytoplasm, cytosol, nucleolus, nucleus ligand-dependent nuclear receptor transcription coactivator activity, protein binding Human WDR81 UniProtKB UniProtKB {GO:0010923=PMID:19389623} Q562E7 WD repeat-containing protein 81 protein 20111103 {GO:0010923=IDA} negative regulation of phosphatase activity Human WDR82 UniProtKB UniProtKB {GO:0005515=PMID:20516061, GO:0035097=PMID:17355966, GO:0048188=PMID:17998332, GO:0003682=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0042800=PMID:17355966, GO:0072357=PMID:20516061, GO:0000785=PMID:20516061, GO:0051568=PMID:17355966} Q6UXN9 WD repeat-containing protein 82 protein 20091109 {GO:0005515=IPI, GO:0035097=IDA, GO:0048188=IDA, GO:0003682=IEA, GO:0005634=IEA, GO:0042800=IDA, GO:0072357=IDA, GO:0000785=IDA, GO:0051568=IDA} histone H3-K4 methylation PTW/PP1 phosphatase complex, Set1C/COMPASS complex, chromatin, histone methyltransferase complex, nucleus chromatin binding, histone methyltransferase activity (H3-K4 specific), protein binding contributes_to Human WDR83 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0000398=PMID:11991638, GO:0016301=GO_REF:0000038, GO:0000375=PMID:11991638, GO:0005681=PMID:11991638, GO:0071013=PMID:11991638} Q9BRX9 WD repeat domain-containing protein 83 protein 20110302 {GO:0005737=IEA, GO:0000398=IC, GO:0016301=IEA, GO:0000375=IDA, GO:0005681=IDA, GO:0071013=IDA} RNA splicing, via transesterification reactions, mRNA splicing, via spliceosome catalytic step 2 spliceosome, cytoplasm, spliceosomal complex kinase activity Human WDR83OS UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q9Y284 Protein Asterix protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 WDR85 UniProtKB UniProtKB {GO:0017183=PMID:19965467} Q9BTV6 WD repeat-containing protein 85 protein 20100907 {GO:0017183=IMP} peptidyl-diphthamide biosynthetic process from peptidyl-histidine Human WDR87 null null {} null null null null {} null null null WDR88 null null {} null null null null {} null null null WDR89 null null {} null null null null {} null null null WDR91 null null {} null null null null {} null null null WDR92 UniProtKB UniProtKB {GO:0034968=PMID:16600877, GO:0006915=GO_REF:0000037, GO:0035064=PMID:16600877} Q96MX6 WD repeat-containing protein 92 protein 20091124 {GO:0034968=IDA, GO:0006915=IEA, GO:0035064=IDA} apoptotic process, histone lysine methylation methylated histone residue binding Human WDR96 null null {} null null null null {} null null null WDTC1 HPA UniProtKB {GO:0005515=PMID:16964240, GO:0004857=GO_REF:0000019, GO:0008361=GO_REF:0000019, GO:0032869=GO_REF:0000019, GO:0042826=GO_REF:0000019, GO:0045717=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0055082=GO_REF:0000019, GO:0043231=GO_REF:0000052, GO:0005829=GO_REF:0000019, GO:0042393=GO_REF:0000019, GO:0035264=GO_REF:0000019, GO:0006006=GO_REF:0000019} Q8N5D0 WD and tetratricopeptide repeats protein 1 protein 20111111 {GO:0005515=IPI, GO:0004857=IEA, GO:0008361=IEA, GO:0032869=IEA, GO:0042826=IEA, GO:0045717=IEA, GO:0005634=IEA, GO:0000122=IEA, GO:0001701=IEA, GO:0055082=IEA, GO:0043231=IDA, GO:0005829=IEA, GO:0042393=IEA, GO:0035264=IEA, GO:0006006=IEA} cellular chemical homeostasis, cellular response to insulin stimulus, glucose metabolic process, in utero embryonic development, multicellular organism growth, negative regulation of fatty acid biosynthetic process, negative regulation of transcription from RNA polymerase II promoter, regulation of cell size cytosol, intracellular membrane-bounded organelle, nucleus enzyme inhibitor activity, histone binding, histone deacetylase binding, protein binding Human WDYHV1 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0070773=GO_REF:0000024, GO:0016811=GO_REF:0000002, GO:0005634=GO_REF:0000024, GO:0006464=GO_REF:0000024, GO:0005829=GO_REF:0000024} Q96HA8 Protein N-terminal glutamine amidohydrolase protein 20130415 {GO:0005515=IPI, GO:0070773=ISS, GO:0016811=IEA, GO:0005634=ISS, GO:0006464=ISS, GO:0005829=ISS} cellular protein modification process cytosol, nucleus hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides, protein binding, protein-N-terminal glutamine amidohydrolase activity Human UniProtKB:Q9UI14 WEE1 IntAct UniProtKB {GO:0005515=PMID:15070733, GO:0000287=GO_REF:0000002, GO:0000226=GO_REF:0000019, GO:0018108=GO_REF:0000019, GO:0030010=GO_REF:0000019, GO:0005634=PMID:8348613, GO:0005524=GO_REF:0000037, GO:0000084=Reactome:REACT_899, GO:0000082=Reactome:REACT_1783, GO:0005737=GO_REF:0000019, GO:0007067=GO_REF:0000037, GO:0007596=Reactome:REACT_604, GO:0004674=GO_REF:0000002, GO:0000086=Reactome:REACT_2203, GO:0048812=GO_REF:0000019, GO:0051726=Reactome:REACT_1006, GO:0000075=Reactome:REACT_1538, GO:0005654=Reactome:REACT_9057, GO:0004713=PMID:7774574, GO:0000278=Reactome:REACT_152, GO:0004715=GO_REF:0000003, GO:0051301=GO_REF:0000037} P30291 Wee1-like protein kinase protein 20130415 {GO:0005515=IPI, GO:0000287=IEA, GO:0000226=IEA, GO:0018108=IEA, GO:0030010=IEA, GO:0005634=TAS, GO:0005524=IEA, GO:0000084=TAS, GO:0000082=TAS, GO:0005737=IEA, GO:0007067=IEA, GO:0007596=TAS, GO:0004674=IEA, GO:0000086=TAS, GO:0048812=IEA, GO:0051726=TAS, GO:0000075=TAS, GO:0005654=TAS, GO:0004713=TAS, GO:0000278=TAS, GO:0004715=IEA, GO:0051301=IEA} G1/S transition of mitotic cell cycle, G2/M transition of mitotic cell cycle, S phase of mitotic cell cycle, blood coagulation, cell cycle checkpoint, cell division, establishment of cell polarity, microtubule cytoskeleton organization, mitosis, mitotic cell cycle, neuron projection morphogenesis, peptidyl-tyrosine phosphorylation, regulation of cell cycle cytoplasm, nucleoplasm, nucleus ATP binding, magnesium ion binding, non-membrane spanning protein tyrosine kinase activity, protein binding, protein serine/threonine kinase activity, protein tyrosine kinase activity Human UniProtKB:Q9Y297 WEE2 HPA UniProtKB {GO:0005813=GO_REF:0000052, GO:0000287=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:1900194=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037, GO:0007128=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0007067=GO_REF:0000002, GO:0060631=GO_REF:0000024, GO:0007343=GO_REF:0000019, GO:0060283=GO_REF:0000019, GO:0004674=GO_REF:0000002, GO:0007137=GO_REF:0000019, GO:0035038=GO_REF:0000024, GO:0007143=GO_REF:0000024, GO:0004715=GO_REF:0000003} P0C1S8 Wee1-like protein kinase 2 protein 20101115 {GO:0005813=IDA, GO:0000287=IEA, GO:0005730=IDA, GO:1900194=ISS, GO:0005634=IDA, GO:0005524=IEA, GO:0007128=IEA, GO:0005737=IDA, GO:0007067=IEA, GO:0060631=ISS, GO:0007343=IEA, GO:0060283=IEA, GO:0004674=IEA, GO:0007137=IEA, GO:0035038=ISS, GO:0007143=ISS, GO:0004715=IEA} egg activation, female meiosis, female pronucleus assembly, meiotic metaphase II, meiotic prophase I, mitosis, negative regulation of oocyte development, negative regulation of oocyte maturation, regulation of meiosis I centrosome, cytoplasm, nucleolus, nucleus ATP binding, magnesium ion binding, non-membrane spanning protein tyrosine kinase activity, protein serine/threonine kinase activity Human WFDC1 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0030308=PMID:10967136, GO:0004867=GO_REF:0000037, GO:0042493=GO_REF:0000019, GO:0050680=GO_REF:0000019, GO:0005615=PMID:10967136, GO:0032355=GO_REF:0000019} Q9HC57 WAP four-disulfide core domain protein 1 protein 20061026 {GO:0003674=ND, GO:0030308=NAS, GO:0004867=IEA, GO:0042493=IEA, GO:0050680=IEA, GO:0005615=NAS, GO:0032355=IEA} negative regulation of cell growth, negative regulation of epithelial cell proliferation, response to drug, response to estradiol stimulus extracellular space molecular_function, serine-type endopeptidase inhibitor activity Human WFDC11 UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q8NEX6 Protein WFDC11 protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 WFDC12 UniProtKB UniProtKB {GO:0004867=PMID:11779191, GO:0005576=GO_REF:0000039, GO:0042742=GO_REF:0000024} Q8WWY7 WAP four-disulfide core domain protein 12 protein 20021112 {GO:0004867=NAS, GO:0005576=IEA, GO:0042742=ISS} defense response to bacterium extracellular region serine-type endopeptidase inhibitor activity Human WFDC2 GOC UniProtKB {GO:0010951=PMID:1686187, GO:0004866=PMID:1686187, GO:0004867=GO_REF:0000037, GO:0006508=PMID:1686187, GO:0005576=GO_REF:0000002, GO:0007283=PMID:1686187, GO:0030414=GO_REF:0000002, GO:0005615=PMID:1686187} Q14508 WAP four-disulfide core domain protein 2 protein 20130413 {GO:0010951=TAS, GO:0004866=TAS, GO:0004867=IEA, GO:0006508=TAS, GO:0005576=IEA, GO:0007283=TAS, GO:0030414=IEA, GO:0005615=TAS} negative regulation of endopeptidase activity, proteolysis, spermatogenesis extracellular region, extracellular space endopeptidase inhibitor activity, peptidase inhibitor activity, serine-type endopeptidase inhibitor activity Human WFDC3 UniProtKB UniProtKB {GO:0004867=GO_REF:0000037, GO:0005576=GO_REF:0000039, GO:0030414=GO_REF:0000002} Q8IUB2 WAP four-disulfide core domain protein 3 protein 20130413 {GO:0004867=IEA, GO:0005576=IEA, GO:0030414=IEA} extracellular region peptidase inhibitor activity, serine-type endopeptidase inhibitor activity Human UniProtKB-SubCell:SL-0243 WFDC5 UniProtKB UniProtKB {GO:0004867=GO_REF:0000037, GO:0005576=GO_REF:0000039} Q8TCV5 WAP four-disulfide core domain protein 5 protein 20130413 {GO:0004867=IEA, GO:0005576=IEA} extracellular region serine-type endopeptidase inhibitor activity Human UniProtKB-SubCell:SL-0243 WFDC8 UniProtKB UniProtKB {GO:0004867=GO_REF:0000037, GO:0005576=GO_REF:0000039} Q8IUA0 WAP four-disulfide core domain protein 8 protein 20130413 {GO:0004867=IEA, GO:0005576=IEA} extracellular region serine-type endopeptidase inhibitor activity Human UniProtKB-SubCell:SL-0243 WFIKKN1 UniProtKB UniProtKB {GO:0004867=GO_REF:0000037, GO:0008191=GO_REF:0000037, GO:0005576=GO_REF:0000039} Q96NZ8 WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1 protein 20130413 {GO:0004867=IEA, GO:0008191=IEA, GO:0005576=IEA} extracellular region metalloendopeptidase inhibitor activity, serine-type endopeptidase inhibitor activity Human UniProtKB-SubCell:SL-0243 WFIKKN2 UniProtKB UniProtKB {GO:0004867=GO_REF:0000037, GO:0008191=GO_REF:0000037, GO:0007179=GO_REF:0000019, GO:0005576=GO_REF:0000039} Q8TEU8 WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 protein 20130413 {GO:0004867=IEA, GO:0008191=IEA, GO:0007179=IEA, GO:0005576=IEA} transforming growth factor beta receptor signaling pathway extracellular region metalloendopeptidase inhibitor activity, serine-type endopeptidase inhibitor activity Human UniProtKB-SubCell:SL-0243 WFS1 BHF-UCL UniProtKB {GO:0005215=GO_REF:0000024, GO:0034976=PMID:15994758, GO:0006983=PMID:16989814, GO:0051928=PMID:16989814, GO:0005783=GO_REF:0000024, GO:0007605=PMID:17492394, GO:0030176=PMID:11181571, GO:0043433=GO_REF:0000024, GO:0030425=PMID:11181571, GO:0022417=PMID:16989814, GO:0055074=PMID:14527944, GO:0030968=GO_REF:0000024, GO:2000675=GO_REF:0000019, GO:0043069=PMID:9771706, GO:0043524=PMID:9771706, GO:0031398=GO_REF:0000024, GO:0051117=PMID:17947299, GO:0033613=GO_REF:0000024, GO:0031625=GO_REF:0000024, GO:0045927=GO_REF:0000024, GO:0051247=PMID:17947299, GO:0043066=GO_REF:0000024, GO:0001822=PMID:9817917, GO:0032469=PMID:16989814, GO:0050821=GO_REF:0000024, GO:0042981=PMID:16087305, GO:0042593=PMID:9817917, GO:0030433=GO_REF:0000024, GO:0045862=GO_REF:0000024, GO:0003091=PMID:9817917, GO:0070845=GO_REF:0000024, GO:0005789=Reactome:REACT_115977, GO:0050877=PMID:9817917, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015, GO:0007601=PMID:9771706} O76024 Wolframin protein 20080507 {GO:0005215=ISS, GO:0034976=IDA, GO:0006983=IC, GO:0051928=IDA, GO:0005783=ISS, GO:0007605=IMP, GO:0030176=IDA, GO:0043433=ISS, GO:0030425=ISS, GO:0022417=IC, GO:0055074=IDA, GO:0030968=ISS, GO:2000675=IEA, GO:0043069=IMP, GO:0043524=IMP, GO:0031398=ISS, GO:0051117=IPI, GO:0033613=ISS, GO:0031625=ISS, GO:0045927=ISS, GO:0051247=IDA, GO:0043066=ISS, GO:0001822=IMP, GO:0032469=IDA, GO:0050821=ISS, GO:0042981=IDA, GO:0042593=IMP, GO:0030433=ISS, GO:0045862=ISS, GO:0003091=IMP, GO:0070845=ISS, GO:0005789=TAS, GO:0050877=IMP, GO:0006987=TAS, GO:0044267=TAS, GO:0007601=IMP} ER overload response, ER-associated protein catabolic process, activation of signaling protein activity involved in unfolded protein response, calcium ion homeostasis, cellular protein metabolic process, endoplasmic reticulum calcium ion homeostasis, endoplasmic reticulum unfolded protein response, glucose homeostasis, kidney development, negative regulation of apoptotic process, negative regulation of neuron apoptotic process, negative regulation of programmed cell death, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of type B pancreatic cell apoptotic process, neurological system process, polyubiquitinated misfolded protein transport, positive regulation of calcium ion transport, positive regulation of growth, positive regulation of protein metabolic process, positive regulation of protein ubiquitination, positive regulation of proteolysis, protein maturation by protein folding, protein stabilization, regulation of apoptotic process, renal water homeostasis, response to endoplasmic reticulum stress, sensory perception of sound, visual perception dendrite, endoplasmic reticulum, endoplasmic reticulum membrane, integral to endoplasmic reticulum membrane ATPase binding, activating transcription factor binding, transporter activity, ubiquitin protein ligase binding Human GO:0032469 WHSC1 HPA UniProtKB {GO:0003289=GO_REF:0000019, GO:0031965=GO_REF:0000052, GO:0005694=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000122=GO_REF:0000019, GO:0009653=PMID:9618163, GO:0003677=GO_REF:0000037, GO:0003290=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0018024=GO_REF:0000003, GO:0060348=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0003149=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0008270=GO_REF:0000002} O96028 Histone-lysine N-methyltransferase NSD2 protein 20090616 {GO:0003289=IEA, GO:0031965=IDA, GO:0005694=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0000122=IEA, GO:0009653=TAS, GO:0003677=IEA, GO:0003290=IEA, GO:0006351=IEA, GO:0018024=IEA, GO:0060348=IEA, GO:0005737=IEA, GO:0003149=IEA, GO:0003682=IEA, GO:0008270=IEA} anatomical structure morphogenesis, atrial septum primum morphogenesis, atrial septum secundum morphogenesis, bone development, membranous septum morphogenesis, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent chromosome, cytoplasm, nuclear membrane, nucleolus, nucleus DNA binding, chromatin binding, histone-lysine N-methyltransferase activity, zinc ion binding Human WHSC1L1 GOC UniProtKB {GO:0006355=GO_REF:0000037, GO:0005694=GO_REF:0000039, GO:0016571=PMID:16682010, GO:0034968=PMID:16682010, GO:0016049=GO_REF:0000029, GO:0005634=PMID:16682010, GO:0008270=GO_REF:0000002, GO:0030154=GO_REF:0000029, GO:0006351=GO_REF:0000037, GO:0018024=PMID:16682010} Q9BZ95 Histone-lysine N-methyltransferase NSD3 protein 20130413 {GO:0006355=IEA, GO:0005694=IEA, GO:0016571=IDA, GO:0034968=IDA, GO:0016049=NAS, GO:0005634=IC, GO:0008270=IEA, GO:0030154=NAS, GO:0006351=IEA, GO:0018024=IDA} cell differentiation, cell growth, histone lysine methylation, histone methylation, regulation of transcription, DNA-dependent, transcription, DNA-dependent chromosome, nucleus histone-lysine N-methyltransferase activity, zinc ion binding Human WIBG HPA UniProtKB {GO:0005515=PMID:19410547, GO:0005737=GO_REF:0000052, GO:0000184=PMID:19410547, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0043022=PMID:18026120, GO:0045727=PMID:18026120, GO:0005654=GO_REF:0000039, GO:0035145=PMID:18026120} Q9BRP8 Partner of Y14 and mago protein 20111111 {GO:0005515=IPI, GO:0005737=IDA, GO:0000184=IDA, GO:0003723=IEA, GO:0005730=IEA, GO:0043022=IDA, GO:0045727=IDA, GO:0005654=IEA, GO:0035145=IDA} nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, positive regulation of translation cytoplasm, exon-exon junction complex, nucleolus, nucleoplasm RNA binding, protein binding, ribosome binding Human WIF1 PINC UniProtKB {GO:0007165=PMID:10201374, GO:0045600=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0016055=GO_REF:0000037} Q9Y5W5 Wnt inhibitory factor 1 protein 20040811 {GO:0007165=NAS, GO:0045600=IEA, GO:0005576=IEA, GO:0007275=IEA, GO:0016055=IEA} Wnt receptor signaling pathway, multicellular organismal development, positive regulation of fat cell differentiation, signal transduction extracellular region Human WIPF1 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0030048=GO_REF:0000019, GO:0030036=GO_REF:0000019, GO:0005884=GO_REF:0000019, GO:0003779=GO_REF:0000037, GO:0015629=PMID:9405671, GO:0001726=GO_REF:0000039, GO:0005829=Reactome:REACT_160291, GO:0046827=GO_REF:0000019, GO:0006461=PMID:9405671, GO:0008154=PMID:9405671, GO:0045087=Reactome:REACT_6802, GO:0016023=GO_REF:0000039, GO:0005522=PMID:9405671, GO:0038096=Reactome:REACT_160123} O43516 WAS/WASL-interacting protein family member 1 protein 20130415 {GO:0005515=IPI, GO:0030048=IEA, GO:0030036=IEA, GO:0005884=IEA, GO:0003779=IEA, GO:0015629=TAS, GO:0001726=IEA, GO:0005829=TAS, GO:0046827=IEA, GO:0006461=TAS, GO:0008154=TAS, GO:0045087=TAS, GO:0016023=IEA, GO:0005522=TAS, GO:0038096=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, actin cytoskeleton organization, actin filament-based movement, actin polymerization or depolymerization, innate immune response, positive regulation of protein export from nucleus, protein complex assembly actin cytoskeleton, actin filament, cytoplasmic membrane-bounded vesicle, cytosol, ruffle actin binding, profilin binding, protein binding Human UniProtKB:P62993 WIPF2 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0045087=Reactome:REACT_6802, GO:0003779=GO_REF:0000037, GO:0005856=GO_REF:0000039, GO:0038096=Reactome:REACT_160123, GO:0005829=Reactome:REACT_160291} Q8TF74 WAS/WASL-interacting protein family member 2 protein 20130415 {GO:0005515=IPI, GO:0045087=TAS, GO:0003779=IEA, GO:0005856=IEA, GO:0038096=TAS, GO:0005829=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, innate immune response cytoskeleton, cytosol actin binding, protein binding Human UniProtKB:P62993 WIPF3 HPA UniProtKB {GO:0017124=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0045087=Reactome:REACT_6802, GO:0005730=GO_REF:0000052, GO:0007275=GO_REF:0000037, GO:0003779=GO_REF:0000002, GO:0007283=GO_REF:0000037, GO:0038096=Reactome:REACT_160123, GO:0030154=GO_REF:0000037, GO:0005829=Reactome:REACT_160291} B8ZZV2 WAS/WASL-interacting protein family member 3 protein 20110516 {GO:0017124=IEA, GO:0005737=IDA, GO:0045087=TAS, GO:0005730=IDA, GO:0007275=IEA, GO:0003779=IEA, GO:0007283=IEA, GO:0038096=TAS, GO:0030154=IEA, GO:0005829=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, cell differentiation, innate immune response, multicellular organismal development, spermatogenesis cytoplasm, cytosol, nucleolus SH3 domain binding, actin binding Human WIPI1 Reactome UniProtKB {GO:0005802=PMID:15020712, GO:0030136=GO_REF:0000039, GO:0030331=PMID:15602573, GO:0000421=PMID:17618624, GO:0005102=PMID:15602573, GO:0080025=PMID:20505359, GO:0006914=PMID:17618624, GO:0000407=PMID:15602573, GO:0032266=PMID:20505359, GO:0050681=PMID:15602573, GO:0030968=Reactome:REACT_18356, GO:0005829=GO_REF:0000033, GO:0005737=PMID:17618624, GO:0034045=PMID:17618624, GO:0048203=PMID:15020712, GO:0000139=Reactome:REACT_116014, GO:0006987=Reactome:REACT_18368, GO:0000045=GO_REF:0000033, GO:0044267=Reactome:REACT_17015, GO:0010008=PMID:15020712} Q5MNZ9 WD repeat domain phosphoinositide-interacting protein 1 protein 20130301 {GO:0005802=IDA, GO:0030136=IEA, GO:0030331=IDA, GO:0000421=IDA, GO:0005102=IDA, GO:0080025=IDA, GO:0006914=IEP, GO:0000407=IDA, GO:0032266=IDA, GO:0050681=IDA, GO:0030968=TAS, GO:0005829=IBA, GO:0005737=IDA, GO:0034045=IDA, GO:0048203=IDA, GO:0000139=TAS, GO:0006987=TAS, GO:0000045=IBA, GO:0044267=TAS, GO:0010008=IDA} activation of signaling protein activity involved in unfolded protein response, autophagic vacuole assembly, autophagy, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, vesicle targeting, trans-Golgi to endosome Golgi membrane, autophagic vacuole membrane, clathrin-coated vesicle, cytoplasm, cytosol, endosome membrane, pre-autophagosomal structure, pre-autophagosomal structure membrane, trans-Golgi network androgen receptor binding, estrogen receptor binding, phosphatidylinositol-3,5-bisphosphate binding, phosphatidylinositol-3-phosphate binding, receptor binding Human WIPI2 HPA UniProtKB {GO:0000046=PMID:20505359, GO:0005515=PMID:21575909, GO:0005776=PMID:20505359, GO:0000421=GO_REF:0000033, GO:0080025=PMID:20505359, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0032266=PMID:20505359, GO:0005829=PMID:20505359, GO:0043234=GO_REF:0000054, GO:0034045=PMID:20505359, GO:0005737=GO_REF:0000052, GO:0000045=PMID:20505359} Q9Y4P8 WD repeat domain phosphoinositide-interacting protein 2 protein 20100326 {GO:0000046=IMP, GO:0005515=IPI, GO:0005776=IDA, GO:0000421=IBA, GO:0080025=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0032266=IDA, GO:0005829=IDA, GO:0043234=IDA, GO:0034045=IDA, GO:0005737=IDA, GO:0000045=IMP} autophagic vacuole assembly, autophagic vacuole fusion autophagic vacuole, autophagic vacuole membrane, cytoplasm, cytosol, nucleolus, nucleus, pre-autophagosomal structure membrane, protein complex phosphatidylinositol-3,5-bisphosphate binding, phosphatidylinositol-3-phosphate binding, protein binding Human WISP1 UniProtKB UniProtKB {GO:0007165=PMID:9843955, GO:0005737=GO_REF:0000052, GO:0007267=PMID:9843955, GO:0005576=GO_REF:0000038, GO:0016055=GO_REF:0000037, GO:0007155=GO_REF:0000037, GO:0005615=PMID:9843955, GO:0001558=GO_REF:0000002, GO:0005520=GO_REF:0000002} Q5JBS7 WISP1tc protein 20130413 {GO:0007165=TAS, GO:0005737=IDA, GO:0007267=TAS, GO:0005576=IEA, GO:0016055=IEA, GO:0007155=IEA, GO:0005615=NAS, GO:0001558=IEA, GO:0005520=IEA} Wnt receptor signaling pathway, cell adhesion, cell-cell signaling, regulation of cell growth, signal transduction cytoplasm, extracellular region, extracellular space insulin-like growth factor binding Human UniProtKB-KW:KW-0964 WISP2 InterPro UniProtKB {GO:0007165=PMID:9843955, GO:0005886=GO_REF:0000019, GO:0007267=PMID:9843955, GO:0005576=GO_REF:0000002, GO:0007155=GO_REF:0000037, GO:0005615=PMID:10358067, GO:0001558=GO_REF:0000002, GO:0005520=GO_REF:0000002} Q6PEG3 WNT1-inducible-signaling pathway protein 2 protein 20130413 {GO:0007165=TAS, GO:0005886=IEA, GO:0007267=TAS, GO:0005576=IEA, GO:0007155=IEA, GO:0005615=IDA, GO:0001558=IEA, GO:0005520=IEA} cell adhesion, cell-cell signaling, regulation of cell growth, signal transduction extracellular region, extracellular space, plasma membrane insulin-like growth factor binding Human InterPro:IPR000867 WIZ UniProtKB UniProtKB {GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002} O95785 Protein Wiz protein 20130413 {GO:0005634=IEA, GO:0008270=IEA} nucleus zinc ion binding Human UniProtKB-SubCell:SL-0191 WLS InterPro UniProtKB {GO:0017147=GO_REF:0000002, GO:0005794=GO_REF:0000019, GO:0001707=GO_REF:0000019, GO:0000139=GO_REF:0000039, GO:0009948=GO_REF:0000019, GO:0090263=PMID:17804805, GO:0004871=GO_REF:0000024, GO:0016021=GO_REF:0000037, GO:0031410=GO_REF:0000019, GO:0043123=GO_REF:0000024, GO:0016055=GO_REF:0000002, GO:0030659=GO_REF:0000039} Q7Z430 Putative NFkB activating protein protein 20130413 {GO:0017147=IEA, GO:0005794=IEA, GO:0001707=IEA, GO:0000139=IEA, GO:0009948=IEA, GO:0090263=IMP, GO:0004871=ISS, GO:0016021=IEA, GO:0031410=IEA, GO:0043123=ISS, GO:0016055=IEA, GO:0030659=IEA} Wnt receptor signaling pathway, anterior/posterior axis specification, mesoderm formation, positive regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of canonical Wnt receptor signaling pathway Golgi apparatus, Golgi membrane, cytoplasmic vesicle, cytoplasmic vesicle membrane, integral to membrane Wnt-protein binding, signal transducer activity Human InterPro:IPR009551 WNK1 IntAct UniProtKB {GO:0005515=PMID:19389623, GO:0019902=PMID:19389623, GO:0090188=GO_REF:0000019, GO:0005524=PMID:10660600, GO:0007243=PMID:10660600, GO:0003084=GO_REF:0000019, GO:0005737=PMID:10660600, GO:0004674=PMID:10660600, GO:0048666=PMID:15060842, GO:0050794=GO_REF:0000024, GO:0010923=PMID:19389623, GO:0004860=GO_REF:0000037, GO:0006468=PMID:10660600, GO:0006811=GO_REF:0000024} Q9H4A3 Serine/threonine-protein kinase WNK1 protein 20130415 {GO:0005515=IPI, GO:0019902=IDA, GO:0090188=IEA, GO:0005524=IDA, GO:0007243=IDA, GO:0003084=IEA, GO:0005737=IDA, GO:0004674=IDA, GO:0048666=NAS, GO:0050794=ISS, GO:0010923=IDA, GO:0004860=IEA, GO:0006468=IDA, GO:0006811=ISS} intracellular protein kinase cascade, ion transport, negative regulation of pancreatic juice secretion, negative regulation of phosphatase activity, neuron development, positive regulation of systemic arterial blood pressure, protein phosphorylation, regulation of cellular process cytoplasm ATP binding, phosphatase binding, protein binding, protein kinase inhibitor activity, protein serine/threonine kinase activity Human UniProtKB:P62136 WNK2 UniProtKB UniProtKB {GO:0005737=PMID:17667937, GO:0008285=PMID:17667937, GO:0046777=PMID:17667937, GO:2000651=PMID:21733846, GO:0005886=GO_REF:0000039, GO:0004674=GO_REF:0000024, GO:0070373=PMID:17667937, GO:0006468=PMID:21733846, GO:0005524=GO_REF:0000024, GO:2000021=PMID:21733846, GO:0007243=GO_REF:0000024, GO:0016772=GO_REF:0000002} Q9Y3S1 Serine/threonine-protein kinase WNK2 protein 20110829 {GO:0005737=IDA, GO:0008285=IMP, GO:0046777=IDA, GO:2000651=IMP, GO:0005886=IEA, GO:0004674=ISS, GO:0070373=IMP, GO:0006468=IDA, GO:0005524=ISS, GO:2000021=IMP, GO:0007243=ISS, GO:0016772=IEA} intracellular protein kinase cascade, negative regulation of ERK1 and ERK2 cascade, negative regulation of cell proliferation, positive regulation of sodium ion transmembrane transporter activity, protein autophosphorylation, protein phosphorylation, regulation of ion homeostasis cytoplasm, plasma membrane ATP binding, protein serine/threonine kinase activity, transferase activity, transferring phosphorus-containing groups Human WNK3 BHF-UCL UniProtKB {GO:0005515=PMID:16501604, GO:0010800=PMID:16275913, GO:0043066=PMID:16501604, GO:2000651=PMID:21613606, GO:0051928=PMID:18768590, GO:2000682=PMID:16275913, GO:0032414=PMID:16275913, GO:0005524=GO_REF:0000024, GO:0007243=GO_REF:0000024, GO:2000688=PMID:16275913, GO:0005737=PMID:16501604, GO:0004672=PMID:16275913, GO:0046777=PMID:16275913, GO:0005912=GO_REF:0000024, GO:0010765=PMID:16275913, GO:0004674=PMID:17975670, GO:0006468=GO_REF:0000024, GO:0005923=GO_REF:0000024, GO:2000021=PMID:21613606, GO:0090004=PMID:16275913} Q9BYP7 Serine/threonine-protein kinase WNK3 protein 20110426 {GO:0005515=IPI, GO:0010800=IDA, GO:0043066=IMP, GO:2000651=IMP, GO:0051928=IMP, GO:2000682=IDA, GO:0032414=IDA, GO:0005524=ISS, GO:0007243=ISS, GO:2000688=IDA, GO:0005737=IDA, GO:0004672=IDA, GO:0046777=IDA, GO:0005912=ISS, GO:0010765=IDA, GO:0004674=IDA, GO:0006468=ISS, GO:0005923=ISS, GO:2000021=IMP, GO:0090004=IDA} intracellular protein kinase cascade, negative regulation of apoptotic process, positive regulation of calcium ion transport, positive regulation of establishment of protein localization to plasma membrane, positive regulation of ion transmembrane transporter activity, positive regulation of peptidyl-threonine phosphorylation, positive regulation of rubidium ion transmembrane transporter activity, positive regulation of rubidium ion transport, positive regulation of sodium ion transmembrane transporter activity, positive regulation of sodium ion transport, protein autophosphorylation, protein phosphorylation, regulation of ion homeostasis adherens junction, cytoplasm, tight junction ATP binding, protein binding, protein kinase activity, protein serine/threonine kinase activity Human UniProtKB:Q80XP9 WNK4 UniProtKB UniProtKB {GO:0006821=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0008104=GO_REF:0000019, GO:0004674=GO_REF:0000024, GO:0050794=GO_REF:0000024, GO:0090188=GO_REF:0000019, GO:0006468=GO_REF:0000024, GO:0005923=GO_REF:0000024, GO:0005524=GO_REF:0000024, GO:0007243=GO_REF:0000024, GO:0006811=GO_REF:0000024} Q96J92 Serine/threonine-protein kinase WNK4 protein 20041006 {GO:0006821=IEA, GO:0005737=IEA, GO:0008104=IEA, GO:0004674=ISS, GO:0050794=ISS, GO:0090188=IEA, GO:0006468=ISS, GO:0005923=ISS, GO:0005524=ISS, GO:0007243=ISS, GO:0006811=ISS} chloride transport, intracellular protein kinase cascade, ion transport, negative regulation of pancreatic juice secretion, protein localization, protein phosphorylation, regulation of cellular process cytoplasm, tight junction ATP binding, protein serine/threonine kinase activity Human UniProtKB:Q80UE6 WNT1 BHF-UCL UniProtKB {GO:0005515=PMID:10347172, GO:0021551=GO_REF:0000024, GO:0001658=GO_REF:0000019, GO:0009798=GO_REF:0000033, GO:2000002=PMID:16501043, GO:0044212=PMID:19847889, GO:0045599=GO_REF:0000024, GO:0005110=GO_REF:0000033, GO:0005615=GO_REF:0000033, GO:0007223=GO_REF:0000033, GO:0009880=GO_REF:0000033, GO:0005109=PMID:19756656, GO:0000578=GO_REF:0000024, GO:0021797=GO_REF:0000033, GO:0035284=GO_REF:0000033, GO:0016055=PMID:10644691, GO:0030579=GO_REF:0000019, GO:0061184=PMID:10654605, GO:0048018=PMID:19778454, GO:0045747=PMID:16501043, GO:0022408=PMID:17072303, GO:0033077=GO_REF:0000033, GO:0042472=GO_REF:0000033, GO:0009986=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0021587=GO_REF:0000033, GO:0007520=GO_REF:0000019, GO:0005125=GO_REF:0000024, GO:0021588=GO_REF:0000024, GO:0042770=PMID:16501043, GO:0071425=GO_REF:0000033, GO:0021592=GO_REF:0000033, GO:0045121=GO_REF:0000033, GO:0045893=PMID:10644691, GO:0021536=GO_REF:0000033, GO:0008284=PMID:16501043, GO:0005886=GO_REF:0000033, GO:0031100=GO_REF:0000019, GO:0007267=GO_REF:0000024, GO:0010812=PMID:16501043, GO:0090344=PMID:16501043, GO:0044336=PMID:12154096, GO:0048146=PMID:19734317, GO:0030514=PMID:16194878, GO:0010592=PMID:19756656, GO:0051091=GO_REF:0000024, GO:0005737=PMID:19756656, GO:0045944=GO_REF:0000019, GO:0071375=GO_REF:0000019, GO:0048332=GO_REF:0000033, GO:0022004=GO_REF:0000033, GO:0060070=PMID:19756656, GO:0030512=GO_REF:0000019, GO:0043066=PMID:19756656, GO:0005770=GO_REF:0000033, GO:0048664=GO_REF:0000033, GO:0009611=PMID:17982423, GO:0005578=GO_REF:0000039, GO:2000059=GO_REF:0000019, GO:0021527=GO_REF:0000019, GO:0043568=PMID:12154096, GO:0001934=GO_REF:0000019, GO:0030901=GO_REF:0000024, GO:0060061=GO_REF:0000024, GO:0005769=GO_REF:0000033, GO:0070365=GO_REF:0000033} P04628 Proto-oncogene Wnt-1 protein 20100708 {GO:0005515=IPI, GO:0021551=ISS, GO:0001658=IEA, GO:0009798=IBA, GO:2000002=IDA, GO:0044212=IDA, GO:0045599=ISS, GO:0005110=IBA, GO:0005615=IBA, GO:0007223=IBA, GO:0009880=IBA, GO:0005109=IC, GO:0000578=ISS, GO:0021797=IBA, GO:0035284=IBA, GO:0016055=IDA, GO:0030579=IEA, GO:0061184=IDA, GO:0048018=IC, GO:0045747=IDA, GO:0022408=IMP, GO:0033077=IBA, GO:0042472=IBA, GO:0009986=IEA, GO:0019904=IEA, GO:0021587=IBA, GO:0007520=IEA, GO:0005125=ISS, GO:0021588=ISS, GO:0042770=IDA, GO:0071425=IBA, GO:0021592=IBA, GO:0045121=IBA, GO:0045893=IDA, GO:0021536=IBA, GO:0008284=IDA, GO:0005886=IBA, GO:0031100=IEA, GO:0007267=ISS, GO:0010812=IDA, GO:0090344=IDA, GO:0044336=IMP, GO:0048146=IMP, GO:0030514=IMP, GO:0010592=IMP, GO:0051091=ISS, GO:0005737=IDA, GO:0045944=IEA, GO:0071375=IEA, GO:0048332=IBA, GO:0022004=IBA, GO:0060070=IMP, GO:0030512=IEA, GO:0043066=IMP, GO:0005770=IBA, GO:0048664=IBA, GO:0009611=IEP, GO:0005578=IEA, GO:2000059=IEA, GO:0021527=IEA, GO:0043568=IDA, GO:0001934=IEA, GO:0030901=ISS, GO:0060061=ISS, GO:0005769=IBA, GO:0070365=IBA} Spemann organizer formation, T cell differentiation in thymus, Wnt receptor signaling pathway, Wnt receptor signaling pathway, calcium modulating pathway, axis specification, brain segmentation, branching involved in ureteric bud morphogenesis, canonical Wnt receptor signaling pathway, canonical Wnt receptor signaling pathway involved in negative regulation of apoptotic process, cell-cell signaling, cellular response to peptide hormone stimulus, central nervous system morphogenesis, cerebellum formation, cerebellum morphogenesis, diencephalon development, embryonic axis specification, embryonic pattern specification, forebrain anterior/posterior pattern specification, fourth ventricle development, hematopoietic stem cell proliferation, hepatocyte differentiation, inner ear morphogenesis, mesoderm morphogenesis, midbrain development, midbrain-hindbrain boundary maturation during brain development, myoblast fusion, negative regulation of BMP signaling pathway, negative regulation of DNA damage checkpoint, negative regulation of apoptotic process, negative regulation of cell aging, negative regulation of cell-cell adhesion, negative regulation of cell-substrate adhesion, negative regulation of fat cell differentiation, negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process, negative regulation of transforming growth factor beta receptor signaling pathway, neuron fate determination, organ regeneration, positive regulation of Notch signaling pathway, positive regulation of cell proliferation, positive regulation of dermatome development, positive regulation of fibroblast proliferation, positive regulation of insulin-like growth factor receptor signaling pathway, positive regulation of lamellipodium assembly, positive regulation of protein phosphorylation, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, response to wounding, signal transduction in response to DNA damage, spinal cord association neuron differentiation, ubiquitin-dependent SMAD protein catabolic process cell surface, cytoplasm, early endosome, extracellular space, late endosome, membrane raft, plasma membrane, proteinaceous extracellular matrix cytokine activity, frizzled binding, frizzled-2 binding, protein binding, protein domain specific binding, receptor agonist activity, transcription regulatory region DNA binding Human WNT10B UniProtKB UniProtKB {GO:0006629=GO_REF:0000019, GO:0008284=GO_REF:0000033, GO:0009798=GO_REF:0000033, GO:0005886=GO_REF:0000033, GO:0071300=GO_REF:0000024, GO:0045599=PMID:10937998, GO:0045899=GO_REF:0000019, GO:0090263=GO_REF:0000019, GO:0050680=GO_REF:0000033, GO:0032434=GO_REF:0000019, GO:0005615=PMID:15135146, GO:0007224=GO_REF:0000033, GO:0051091=GO_REF:0000019, GO:0030858=GO_REF:0000033, GO:0050909=GO_REF:0000019, GO:0002062=PMID:15135146, GO:0030182=GO_REF:0000024, GO:0000086=GO_REF:0000019, GO:0071374=GO_REF:0000019, GO:0007050=GO_REF:0000019, GO:0016055=GO_REF:0000038, GO:0060070=PMID:17761539, GO:0014835=GO_REF:0000033, GO:0048018=PMID:17761539, GO:0043065=PMID:17761539, GO:0001664=GO_REF:0000033, GO:0030501=GO_REF:0000033, GO:0050821=PMID:10937998, GO:0005578=GO_REF:0000040, GO:0005102=GO_REF:0000002, GO:0048741=GO_REF:0000033, GO:0007275=GO_REF:0000038, GO:0000122=GO_REF:0000019, GO:0051885=GO_REF:0000033, GO:0048641=GO_REF:0000033, GO:0045669=GO_REF:0000033, GO:0008585=GO_REF:0000033, GO:0071425=PMID:9787155, GO:0010971=GO_REF:0000019, GO:0060346=GO_REF:0000033, GO:0030917=GO_REF:0000033, GO:0043586=GO_REF:0000033, GO:0071320=GO_REF:0000019, GO:0061196=GO_REF:0000019} Q4VAJ4 Protein Wnt protein 20130413 {GO:0006629=IEA, GO:0008284=IBA, GO:0009798=IBA, GO:0005886=IBA, GO:0071300=ISS, GO:0045599=IDA, GO:0045899=IEA, GO:0090263=IEA, GO:0050680=IBA, GO:0032434=IEA, GO:0005615=NAS, GO:0007224=IBA, GO:0051091=IEA, GO:0030858=IBA, GO:0050909=IEA, GO:0002062=IEP, GO:0030182=ISS, GO:0000086=IEA, GO:0071374=IEA, GO:0007050=IEA, GO:0016055=IEA, GO:0060070=IDA, GO:0014835=IBA, GO:0048018=IC, GO:0043065=IMP, GO:0001664=IBA, GO:0030501=IBA, GO:0050821=IDA, GO:0005578=IEA, GO:0005102=IEA, GO:0048741=IBA, GO:0007275=IEA, GO:0000122=IEA, GO:0051885=IBA, GO:0048641=IBA, GO:0045669=IBA, GO:0008585=IBA, GO:0071425=IDA, GO:0010971=IEA, GO:0060346=IBA, GO:0030917=IBA, GO:0043586=IBA, GO:0071320=IEA, GO:0061196=IEA} G2/M transition of mitotic cell cycle, Wnt receptor signaling pathway, axis specification, bone trabecula formation, canonical Wnt receptor signaling pathway, cell cycle arrest, cellular response to cAMP, cellular response to parathyroid hormone stimulus, cellular response to retinoic acid, chondrocyte differentiation, female gonad development, fungiform papilla development, hematopoietic stem cell proliferation, lipid metabolic process, midbrain-hindbrain boundary development, multicellular organismal development, myoblast differentiation involved in skeletal muscle regeneration, negative regulation of epithelial cell proliferation, negative regulation of fat cell differentiation, negative regulation of transcription from RNA polymerase II promoter, neuron differentiation, positive regulation of G2/M transition of mitotic cell cycle, positive regulation of RNA polymerase II transcriptional preinitiation complex assembly, positive regulation of anagen, positive regulation of apoptotic process, positive regulation of bone mineralization, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of cell proliferation, positive regulation of epithelial cell differentiation, positive regulation of osteoblast differentiation, positive regulation of sequence-specific DNA binding transcription factor activity, protein stabilization, regulation of proteasomal ubiquitin-dependent protein catabolic process, regulation of skeletal muscle tissue development, sensory perception of taste, skeletal muscle fiber development, smoothened signaling pathway, tongue development extracellular space, plasma membrane, proteinaceous extracellular matrix G-protein coupled receptor binding, receptor agonist activity, receptor binding Human UniProtKB-SubCell:SL-0111 WNT11 GOC UniProtKB {GO:0030308=PMID:20103596, GO:0009798=GO_REF:0000033, GO:0044212=PMID:19847889, GO:0071300=GO_REF:0000024, GO:0032915=GO_REF:0000033, GO:0048706=PMID:9757009, GO:0061101=PMID:20219091, GO:0048844=GO_REF:0000033, GO:0060675=PMID:9757009, GO:0005615=GO_REF:0000033, GO:0070830=GO_REF:0000033, GO:0072177=PMID:9757009, GO:0045860=PMID:20219091, GO:0060548=PMID:20219091, GO:0016055=GO_REF:0000038, GO:0072201=GO_REF:0000019, GO:0030336=PMID:20103596, GO:0030335=PMID:20219091, GO:0007275=GO_REF:0000038, GO:0001649=GO_REF:0000033, GO:0032320=PMID:20103596, GO:0051496=PMID:20103596, GO:0060484=PMID:9757009, GO:0045893=PMID:19847889, GO:0045892=PMID:20103596, GO:0035567=GO_REF:0000019, GO:0005886=GO_REF:0000033, GO:0030325=PMID:9757009, GO:0030282=GO_REF:0000033, GO:0009952=GO_REF:0000033, GO:0005737=PMID:20103596, GO:0090037=PMID:20103596, GO:0030182=GO_REF:0000024, GO:0060021=PMID:18413325, GO:0060070=GO_REF:0000019, GO:0090090=PMID:20103596, GO:0043066=PMID:20219091, GO:0043065=GO_REF:0000019, GO:0001664=GO_REF:0000033, GO:0060412=GO_REF:0000033, GO:0005102=GO_REF:0000002, GO:0005578=GO_REF:0000039, GO:0090272=GO_REF:0000019, GO:0030295=PMID:20103596, GO:0003151=GO_REF:0000033, GO:0010628=PMID:20219091, GO:0005099=PMID:20103596, GO:0007492=GO_REF:0000033, GO:0060197=PMID:9757009, GO:0034394=PMID:20103596, GO:0061037=PMID:9757009, GO:0006468=PMID:20103596} O96014 Protein Wnt-11 protein 20130413 {GO:0030308=IMP, GO:0009798=IBA, GO:0044212=IDA, GO:0071300=ISS, GO:0032915=IBA, GO:0048706=IEP, GO:0061101=IMP, GO:0048844=IBA, GO:0060675=IEP, GO:0005615=IBA, GO:0070830=IBA, GO:0072177=IEP, GO:0045860=IMP, GO:0060548=IMP, GO:0016055=IEA, GO:0072201=IEA, GO:0030336=IMP, GO:0030335=IMP, GO:0007275=IEA, GO:0001649=IBA, GO:0032320=IMP, GO:0051496=IMP, GO:0060484=IEP, GO:0045893=IMP, GO:0045892=IMP, GO:0035567=IEA, GO:0005886=IBA, GO:0030325=IEP, GO:0030282=IBA, GO:0009952=IBA, GO:0005737=IDA, GO:0090037=IMP, GO:0030182=ISS, GO:0060021=IMP, GO:0060070=IEA, GO:0090090=IMP, GO:0043066=IMP, GO:0043065=IEA, GO:0001664=IBA, GO:0060412=IBA, GO:0005102=IEA, GO:0005578=IEA, GO:0090272=IEA, GO:0030295=IMP, GO:0003151=IBA, GO:0010628=IMP, GO:0005099=IMP, GO:0007492=IBA, GO:0060197=IEP, GO:0034394=IMP, GO:0061037=NAS, GO:0006468=IMP} Wnt receptor signaling pathway, adrenal gland development, anterior/posterior pattern specification, artery morphogenesis, axis specification, bone mineralization, canonical Wnt receptor signaling pathway, cellular response to retinoic acid, cloacal septation, embryonic skeletal system development, endoderm development, lung-associated mesenchyme development, mesonephric duct development, multicellular organismal development, negative regulation of apoptotic process, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cartilage development, negative regulation of cell death, negative regulation of cell growth, negative regulation of cell migration, negative regulation of fibroblast growth factor production, negative regulation of mesenchymal cell proliferation, negative regulation of transcription, DNA-dependent, neuroendocrine cell differentiation, neuron differentiation, non-canonical Wnt receptor signaling pathway, osteoblast differentiation, outflow tract morphogenesis, palate development, positive regulation of Ras GTPase activity, positive regulation of apoptotic process, positive regulation of cell migration, positive regulation of gene expression, positive regulation of protein kinase C signaling cascade, positive regulation of protein kinase activity, positive regulation of stress fiber assembly, positive regulation of transcription, DNA-dependent, positive regulation of transforming growth factor beta2 production, protein localization to cell surface, protein phosphorylation, tight junction assembly, ureteric bud morphogenesis, ventricular septum morphogenesis cytoplasm, extracellular space, plasma membrane, proteinaceous extracellular matrix G-protein coupled receptor binding, Ras GTPase activator activity, protein kinase activator activity, receptor binding, transcription regulatory region DNA binding Human WNT16 BHF-UCL UniProtKB {GO:0003408=PMID:16258938, GO:0009798=GO_REF:0000033, GO:0005886=GO_REF:0000033, GO:0005102=GO_REF:0000002, GO:0005578=GO_REF:0000039, GO:0046330=PMID:17200136, GO:0090403=PMID:19951988, GO:0014068=PMID:19951988, GO:0007275=GO_REF:0000038, GO:0007409=GO_REF:0000033, GO:0009952=GO_REF:0000033, GO:0005615=PMID:10500199, GO:0043616=PMID:17200136, GO:0010628=PMID:16007226, GO:0005109=GO_REF:0000033, GO:0060317=GO_REF:0000019, GO:0005737=PMID:17200136, GO:0030216=PMID:17200136, GO:0060548=PMID:17200136, GO:0090399=PMID:19951988, GO:0016055=GO_REF:0000038, GO:0060070=GO_REF:0000033} Q9UBV4 Protein Wnt-16 protein 20100708 {GO:0003408=ISS, GO:0009798=IBA, GO:0005886=IBA, GO:0005102=IEA, GO:0005578=IEA, GO:0046330=IMP, GO:0090403=IMP, GO:0014068=IMP, GO:0007275=IEA, GO:0007409=IBA, GO:0009952=IBA, GO:0005615=IDA, GO:0043616=IMP, GO:0010628=IMP, GO:0005109=IBA, GO:0060317=IEA, GO:0005737=IDA, GO:0030216=IMP, GO:0060548=IMP, GO:0090399=IMP, GO:0016055=IEA, GO:0060070=IBA} Wnt receptor signaling pathway, anterior/posterior pattern specification, axis specification, axonogenesis, canonical Wnt receptor signaling pathway, cardiac epithelial to mesenchymal transition, keratinocyte differentiation, keratinocyte proliferation, multicellular organismal development, negative regulation of cell death, optic cup formation involved in camera-type eye development, oxidative stress-induced premature senescence, positive regulation of JNK cascade, positive regulation of gene expression, positive regulation of phosphatidylinositol 3-kinase cascade, replicative senescence cytoplasm, extracellular space, plasma membrane, proteinaceous extracellular matrix frizzled binding, receptor binding Human UniProtKB:Q3L248 WNT2 BHF-UCL UniProtKB {GO:0060045=GO_REF:0000033, GO:0008284=PMID:10347172, GO:0005886=PMID:19038973, GO:0071300=GO_REF:0000024, GO:0090263=PMID:17948129, GO:0007267=PMID:10557084, GO:0071560=PMID:15040835, GO:0061072=PMID:16258938, GO:0005110=GO_REF:0000033, GO:0048146=PMID:19734317, GO:0005615=GO_REF:0000033, GO:0009950=GO_REF:0000033, GO:0005109=PMID:19038973, GO:0060317=GO_REF:0000033, GO:0051091=PMID:10557084, GO:0005737=PMID:19239325, GO:0002088=PMID:16258938, GO:0045944=GO_REF:0000033, GO:0060501=GO_REF:0000033, GO:0030182=GO_REF:0000024, GO:0060492=GO_REF:0000033, GO:0060716=GO_REF:0000033, GO:0016055=PMID:10557084, GO:0060070=PMID:10347172, GO:0048018=PMID:17948129, GO:0055009=GO_REF:0000033, GO:0061180=PMID:8168088, GO:0005578=GO_REF:0000039, GO:0005102=GO_REF:0000002, GO:0007275=GO_REF:0000038, GO:0005576=PMID:2971536, GO:0002053=GO_REF:0000033, GO:0005125=PMID:10557084, GO:0031012=PMID:15507471} P09544 Protein Wnt-2 protein 20100708 {GO:0060045=IBA, GO:0008284=IDA, GO:0005886=IDA, GO:0071300=ISS, GO:0090263=IMP, GO:0007267=IDA, GO:0071560=IEP, GO:0061072=ISS, GO:0005110=IBA, GO:0048146=IMP, GO:0005615=IBA, GO:0009950=IBA, GO:0005109=IPI, GO:0060317=IBA, GO:0051091=IDA, GO:0005737=IDA, GO:0002088=ISS, GO:0045944=IBA, GO:0060501=IBA, GO:0030182=ISS, GO:0060492=IBA, GO:0060716=IBA, GO:0016055=IDA, GO:0060070=IDA, GO:0048018=IC, GO:0055009=IBA, GO:0061180=IEP, GO:0005578=IEA, GO:0005102=IEA, GO:0007275=IEA, GO:0005576=NAS, GO:0002053=IBA, GO:0005125=IDA, GO:0031012=IDA} Wnt receptor signaling pathway, atrial cardiac muscle tissue morphogenesis, canonical Wnt receptor signaling pathway, cardiac epithelial to mesenchymal transition, cell-cell signaling, cellular response to retinoic acid, cellular response to transforming growth factor beta stimulus, dorsal/ventral axis specification, iris morphogenesis, labyrinthine layer blood vessel development, lens development in camera-type eye, lung induction, mammary gland epithelium development, multicellular organismal development, neuron differentiation, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of cardiac muscle cell proliferation, positive regulation of cell proliferation, positive regulation of epithelial cell proliferation involved in lung morphogenesis, positive regulation of fibroblast proliferation, positive regulation of mesenchymal cell proliferation, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter cytoplasm, extracellular matrix, extracellular region, extracellular space, plasma membrane, proteinaceous extracellular matrix cytokine activity, frizzled binding, frizzled-2 binding, receptor agonist activity, receptor binding Human UniProtKB:Q3L257 WNT2B BHF-UCL UniProtKB {GO:0005886=GO_REF:0000033, GO:0090263=PMID:11741304, GO:0005102=GO_REF:0000002, GO:0005578=GO_REF:0000039, GO:0061072=PMID:16258938, GO:0005110=GO_REF:0000033, GO:0005615=PMID:15135146, GO:0007223=GO_REF:0000033, GO:0009950=GO_REF:0000033, GO:0021871=PMID:15164427, GO:0061303=PMID:16258938, GO:0071425=PMID:9787155, GO:0060638=GO_REF:0000019, GO:0002088=PMID:16258938, GO:0002062=PMID:15135146, GO:0030182=GO_REF:0000024, GO:0060492=GO_REF:0000033, GO:0016055=PMID:15135146, GO:0060070=GO_REF:0000019, GO:0008584=PMID:17848411, GO:0090190=GO_REF:0000033} Q93097 Protein Wnt-2b protein 20100708 {GO:0005886=IBA, GO:0090263=IDA, GO:0005102=IEA, GO:0005578=IEA, GO:0061072=ISS, GO:0005110=IBA, GO:0005615=NAS, GO:0007223=IBA, GO:0009950=IBA, GO:0021871=IEP, GO:0061303=ISS, GO:0071425=IDA, GO:0060638=IEA, GO:0002088=ISS, GO:0002062=IEP, GO:0030182=ISS, GO:0060492=IBA, GO:0016055=IMP, GO:0060070=IEA, GO:0008584=IEP, GO:0090190=IBA} Wnt receptor signaling pathway, Wnt receptor signaling pathway, calcium modulating pathway, canonical Wnt receptor signaling pathway, chondrocyte differentiation, cornea development in camera-type eye, dorsal/ventral axis specification, forebrain regionalization, hematopoietic stem cell proliferation, iris morphogenesis, lens development in camera-type eye, lung induction, male gonad development, mesenchymal-epithelial cell signaling, neuron differentiation, positive regulation of branching involved in ureteric bud morphogenesis, positive regulation of canonical Wnt receptor signaling pathway extracellular space, plasma membrane, proteinaceous extracellular matrix frizzled-2 binding, receptor binding Human UniProtKB:Q98SN7 WNT3 BHF-UCL UniProtKB {GO:0008284=GO_REF:0000033, GO:0060064=GO_REF:0000033, GO:0005886=GO_REF:0000033, GO:0071300=GO_REF:0000024, GO:0045599=GO_REF:0000033, GO:0048843=GO_REF:0000019, GO:0044339=PMID:20039315, GO:0044338=PMID:20039315, GO:0005110=GO_REF:0000033, GO:0005615=PMID:18313787, GO:0007223=GO_REF:0000033, GO:0009950=GO_REF:0000033, GO:0005109=PMID:18313787, GO:0009880=GO_REF:0000033, GO:0009948=GO_REF:0000019, GO:0007411=GO_REF:0000019, GO:0030182=GO_REF:0000024, GO:0060070=PMID:15588944, GO:0048018=PMID:18044981, GO:0001707=GO_REF:0000033, GO:0042472=GO_REF:0000033, GO:0005770=GO_REF:0000033, GO:0061180=PMID:8168088, GO:0019904=GO_REF:0000019, GO:0005578=GO_REF:0000039, GO:0010628=GO_REF:0000019, GO:0000902=PMID:15588944, GO:0048697=GO_REF:0000019, GO:0071425=GO_REF:0000033, GO:0060323=GO_REF:0000033, GO:0035116=GO_REF:0000033, GO:0060174=PMID:14872406, GO:0030917=GO_REF:0000033, GO:0045121=GO_REF:0000033, GO:0035115=GO_REF:0000033, GO:0005769=GO_REF:0000033} P56703 Proto-oncogene Wnt-3 protein 20100930 {GO:0008284=IBA, GO:0060064=IBA, GO:0005886=IBA, GO:0071300=ISS, GO:0045599=IBA, GO:0048843=IEA, GO:0044339=IMP, GO:0044338=IMP, GO:0005110=IBA, GO:0005615=TAS, GO:0007223=IBA, GO:0009950=IBA, GO:0005109=IPI, GO:0009880=IBA, GO:0009948=IEA, GO:0007411=IEA, GO:0030182=ISS, GO:0060070=IDA, GO:0048018=IC, GO:0001707=IBA, GO:0042472=IBA, GO:0005770=IBA, GO:0061180=IEP, GO:0019904=IEA, GO:0005578=IEA, GO:0010628=IEA, GO:0000902=IMP, GO:0048697=IEA, GO:0071425=IBA, GO:0060323=IBA, GO:0035116=IBA, GO:0060174=IMP, GO:0030917=IBA, GO:0045121=IBA, GO:0035115=IBA, GO:0005769=IBA} Spemann organizer formation at the anterior end of the primitive streak, Wnt receptor signaling pathway, calcium modulating pathway, anterior/posterior axis specification, axon guidance, canonical Wnt receptor signaling pathway, canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation, canonical Wnt receptor signaling pathway involved in osteoblast differentiation, cell morphogenesis, cellular response to retinoic acid, dorsal/ventral axis specification, embryonic forelimb morphogenesis, embryonic hindlimb morphogenesis, embryonic pattern specification, head morphogenesis, hematopoietic stem cell proliferation, inner ear morphogenesis, limb bud formation, mammary gland epithelium development, mesoderm formation, midbrain-hindbrain boundary development, negative regulation of axon extension involved in axon guidance, negative regulation of fat cell differentiation, neuron differentiation, positive regulation of cell proliferation, positive regulation of collateral sprouting in absence of injury, positive regulation of gene expression early endosome, extracellular space, late endosome, membrane raft, plasma membrane, proteinaceous extracellular matrix frizzled binding, frizzled-2 binding, protein domain specific binding, receptor agonist activity Human WNT3A UniProtKB UniProtKB {GO:0005515=PMID:22682250, GO:0009798=GO_REF:0000033, GO:0071300=GO_REF:0000024, GO:0045599=GO_REF:0000033, GO:0001756=GO_REF:0000033, GO:0090263=PMID:17976063, GO:0048843=GO_REF:0000019, GO:2000049=GO_REF:0000019, GO:0030879=GO_REF:0000033, GO:0005110=GO_REF:0000033, GO:0007409=GO_REF:0000033, GO:0005615=GO_REF:0000024, GO:0009653=GO_REF:0000029, GO:0007223=GO_REF:0000033, GO:0001947=GO_REF:0000019, GO:0009880=GO_REF:0000033, GO:0007411=GO_REF:0000019, GO:0030198=GO_REF:0000033, GO:0016055=GO_REF:0000038, GO:0061184=PMID:10654605, GO:0048018=PMID:20723538, GO:0048337=PMID:20559569, GO:0042472=GO_REF:0000033, GO:0009986=GO_REF:0000024, GO:0010387=GO_REF:0000024, GO:0003713=GO_REF:0000024, GO:0019904=GO_REF:0000019, GO:0007275=GO_REF:0000038, GO:0021874=GO_REF:0000033, GO:0001701=GO_REF:0000019, GO:0001649=GO_REF:0000019, GO:2000081=GO_REF:0000019, GO:2000727=PMID:20559569, GO:0070507=GO_REF:0000019, GO:0043280=GO_REF:0000019, GO:0048697=GO_REF:0000019, GO:0071425=GO_REF:0000033, GO:0003136=PMID:19736317, GO:0010977=GO_REF:0000024, GO:0030917=GO_REF:0000033, GO:0045121=GO_REF:0000033, GO:0045893=GO_REF:0000024, GO:0048343=GO_REF:0000033, GO:0021846=GO_REF:0000024, GO:0007368=GO_REF:0000033, GO:0008284=GO_REF:0000024, GO:0005886=GO_REF:0000033, GO:0030890=GO_REF:0000019, GO:0061098=GO_REF:0000019, GO:0007267=GO_REF:0000029, GO:0035413=PMID:20137080, GO:0035914=GO_REF:0000019, GO:0032092=PMID:16890161, GO:0090245=GO_REF:0000019, GO:0060026=GO_REF:0000033, GO:0033138=PMID:20723538, GO:0051091=GO_REF:0000019, GO:0050768=GO_REF:0000024, GO:0045944=PMID:20723538, GO:0030182=GO_REF:0000024, GO:0061317=PMID:20559569, GO:0060021=PMID:18413325, GO:0021904=GO_REF:0000033, GO:0060070=PMID:20137080, GO:0005770=GO_REF:0000033, GO:0005102=GO_REF:0000002, GO:0005578=GO_REF:0000040, GO:0005576=GO_REF:0000029, GO:0021527=GO_REF:0000019, GO:0036342=GO_REF:0000019, GO:0070527=GO_REF:0000019, GO:0021766=GO_REF:0000033, GO:0001934=PMID:20137080, GO:0034613=GO_REF:0000019, GO:0030903=GO_REF:0000033, GO:0002092=PMID:16890161, GO:0005769=GO_REF:0000033, GO:0005201=GO_REF:0000029} Q3SY79 Protein Wnt protein 20130413 {GO:0005515=IPI, GO:0009798=IBA, GO:0071300=ISS, GO:0045599=IBA, GO:0001756=IBA, GO:0090263=IDA, GO:0048843=IEA, GO:2000049=IEA, GO:0030879=IBA, GO:0005110=IBA, GO:0007409=IBA, GO:0005615=ISS, GO:0009653=NAS, GO:0007223=IBA, GO:0001947=IEA, GO:0009880=IBA, GO:0007411=IEA, GO:0030198=IBA, GO:0016055=IEA, GO:0061184=IDA, GO:0048018=IDA, GO:0048337=IDA, GO:0042472=IBA, GO:0009986=ISS, GO:0010387=ISS, GO:0003713=ISS, GO:0019904=IEA, GO:0007275=IEA, GO:0021874=IBA, GO:0001701=IEA, GO:0001649=IEA, GO:2000081=IEA, GO:2000727=IDA, GO:0070507=IEA, GO:0043280=IEA, GO:0048697=IEA, GO:0071425=IBA, GO:0003136=IDA, GO:0010977=ISS, GO:0030917=IBA, GO:0045121=IBA, GO:0045893=ISS, GO:0048343=IBA, GO:0021846=ISS, GO:0007368=IBA, GO:0008284=ISS, GO:0005886=IBA, GO:0030890=IEA, GO:0061098=IEA, GO:0007267=NAS, GO:0035413=IDA, GO:0035914=IEA, GO:0032092=IDA, GO:0090245=IEA, GO:0060026=IBA, GO:0033138=IDA, GO:0051091=IEA, GO:0050768=ISS, GO:0045944=IDA, GO:0030182=ISS, GO:0061317=IDA, GO:0060021=IMP, GO:0021904=IBA, GO:0060070=IDA, GO:0005770=IBA, GO:0005102=IEA, GO:0005578=IEA, GO:0005576=NAS, GO:0021527=IEA, GO:0036342=IEA, GO:0070527=IEA, GO:0021766=IBA, GO:0001934=IDA, GO:0034613=IEA, GO:0030903=IBA, GO:0002092=IDA, GO:0005769=IBA, GO:0005201=NAS} Wnt receptor signaling pathway, Wnt receptor signaling pathway involved in forebrain neuroblast division, Wnt receptor signaling pathway, calcium modulating pathway, anatomical structure morphogenesis, axis elongation involved in somitogenesis, axis specification, axon guidance, axonogenesis, canonical Wnt receptor signaling pathway, canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment, cell proliferation in forebrain, cell-cell signaling, cellular protein localization, cellular response to retinoic acid, convergent extension, determination of left/right symmetry, dorsal/ventral neural tube patterning, embryonic pattern specification, extracellular matrix organization, heart looping, hematopoietic stem cell proliferation, hippocampus development, in utero embryonic development, inner ear morphogenesis, mammary gland development, midbrain-hindbrain boundary development, multicellular organismal development, negative regulation of axon extension involved in axon guidance, negative regulation of fat cell differentiation, negative regulation of heart induction by canonical Wnt receptor signaling pathway, negative regulation of neurogenesis, negative regulation of neuron projection development, neuron differentiation, notochord development, osteoblast differentiation, palate development, paraxial mesodermal cell fate commitment, platelet aggregation, positive regulation of B cell proliferation, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation, positive regulation of cardiac muscle cell differentiation, positive regulation of catenin import into nucleus, positive regulation of cell proliferation, positive regulation of cell-cell adhesion mediated by cadherin, positive regulation of collateral sprouting in absence of injury, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of dermatome development, positive regulation of mesodermal cell fate specification, positive regulation of peptidyl-serine phosphorylation, positive regulation of protein binding, positive regulation of protein phosphorylation, positive regulation of protein tyrosine kinase activity, positive regulation of receptor internalization, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, post-anal tail morphogenesis, regulation of microtubule cytoskeleton organization, signalosome assembly, skeletal muscle cell differentiation, somitogenesis, spinal cord association neuron differentiation cell surface, early endosome, extracellular region, extracellular space, late endosome, membrane raft, plasma membrane, proteinaceous extracellular matrix extracellular matrix structural constituent, frizzled-2 binding, protein binding, protein domain specific binding, receptor agonist activity, receptor binding, transcription coactivator activity Human UniProtKB-SubCell:SL-0111 WNT4 BHF-UCL UniProtKB {GO:0001656=GO_REF:0000033, GO:0018345=PMID:15317892, GO:0001658=GO_REF:0000033, GO:0072034=GO_REF:0000019, GO:0009798=GO_REF:0000033, GO:0072033=GO_REF:0000033, GO:0006702=PMID:16959810, GO:0038030=PMID:17720811, GO:0090263=PMID:16959810, GO:0033080=GO_REF:0000019, GO:0071560=PMID:15040835, GO:0005615=PMID:16959810, GO:0010894=PMID:15317892, GO:0048599=GO_REF:0000033, GO:0005109=GO_REF:0000019, GO:0072273=GO_REF:0000019, GO:0016055=GO_REF:0000038, GO:0061184=PMID:10654605, GO:0048018=PMID:16959810, GO:0022407=GO_REF:0000019, GO:0033077=GO_REF:0000033, GO:0030501=PMID:17720811, GO:0005794=GO_REF:0000033, GO:0009986=GO_REF:0000024, GO:0003714=GO_REF:0000024, GO:0061369=PMID:12949260, GO:0060231=GO_REF:0000019, GO:0007275=GO_REF:0000038, GO:0001889=PMID:15312687, GO:2000225=PMID:12949260, GO:0045836=GO_REF:0000019, GO:0032967=PMID:17720811, GO:0042445=GO_REF:0000019, GO:0045596=GO_REF:0000019, GO:0045893=PMID:11283799, GO:0045892=GO_REF:0000024, GO:0051145=GO_REF:0000033, GO:0035567=GO_REF:0000019, GO:0005886=GO_REF:0000033, GO:0030325=PMID:12844346, GO:0001838=GO_REF:0000019, GO:0007267=GO_REF:0000029, GO:0060129=GO_REF:0000033, GO:0001837=PMID:12841867, GO:2000066=PMID:16981135, GO:0009952=GO_REF:0000033, GO:0060126=GO_REF:0000033, GO:0005737=PMID:16959810, GO:0030237=PMID:11283799, GO:0060070=PMID:15317892, GO:0090090=PMID:17976063, GO:0060748=GO_REF:0000033, GO:0043066=GO_REF:0000019, GO:0001664=GO_REF:0000033, GO:0001822=PMID:15312687, GO:0061180=PMID:8168088, GO:0005578=GO_REF:0000039, GO:0005102=GO_REF:0000002, GO:2000019=PMID:11283799, GO:0005576=GO_REF:0000002, GO:0045669=PMID:17720811, GO:0008585=GO_REF:0000024, GO:0007492=GO_REF:0000033, GO:0061205=PMID:18182450, GO:0010629=PMID:15317892, GO:0040037=GO_REF:0000033, GO:0072162=PMID:16368682, GO:0090002=PMID:17976063, GO:0032349=PMID:16981135, GO:0008584=PMID:11283799, GO:0072164=GO_REF:0000033, GO:0005201=GO_REF:0000029} P56705 Protein Wnt-4 protein 20100715 {GO:0001656=IBA, GO:0018345=IDA, GO:0001658=IBA, GO:0072034=IEA, GO:0009798=IBA, GO:0072033=IBA, GO:0006702=IDA, GO:0038030=IDA, GO:0090263=IDA, GO:0033080=IEA, GO:0071560=IEP, GO:0005615=IDA, GO:0010894=IDA, GO:0048599=IBA, GO:0005109=IEA, GO:0072273=IEA, GO:0016055=IEA, GO:0061184=IDA, GO:0048018=IC, GO:0022407=IEA, GO:0033077=IBA, GO:0030501=IDA, GO:0005794=IBA, GO:0009986=ISS, GO:0003714=ISS, GO:0061369=IMP, GO:0060231=IEA, GO:0007275=IEA, GO:0001889=IEP, GO:2000225=IMP, GO:0045836=IEA, GO:0032967=IDA, GO:0042445=IEA, GO:0045596=IEA, GO:0045893=ISS, GO:0045892=ISS, GO:0051145=IBA, GO:0035567=IEA, GO:0005886=IBA, GO:0030325=IEP, GO:0001838=IEA, GO:0007267=NAS, GO:0060129=IBA, GO:0001837=IEP, GO:2000066=IDA, GO:0009952=IBA, GO:0060126=IBA, GO:0005737=IDA, GO:0030237=IMP, GO:0060070=IDA, GO:0090090=IDA, GO:0060748=IBA, GO:0043066=IEA, GO:0001664=IBA, GO:0001822=IEP, GO:0061180=IEP, GO:0005578=IEA, GO:0005102=IEA, GO:2000019=IMP, GO:0005576=IEA, GO:0045669=IDA, GO:0008585=ISS, GO:0007492=IBA, GO:0061205=IMP, GO:0010629=IDA, GO:0040037=IBA, GO:0072162=NAS, GO:0090002=IDA, GO:0032349=IDA, GO:0008584=IMP, GO:0072164=IBA, GO:0005201=NAS} T cell differentiation in thymus, Wnt receptor signaling pathway, adrenal gland development, androgen biosynthetic process, anterior/posterior pattern specification, axis specification, branching involved in ureteric bud morphogenesis, canonical Wnt receptor signaling pathway, cell-cell signaling, cellular response to transforming growth factor beta stimulus, embryonic epithelial tube formation, endoderm development, epithelial to mesenchymal transition, establishment of protein localization to plasma membrane, female gonad development, female sex determination, hormone metabolic process, immature T cell proliferation in thymus, kidney development, liver development, male gonad development, mammary gland epithelium development, mesenchymal to epithelial transition, mesonephric tubule development, metanephric mesenchymal cell differentiation, metanephric nephron morphogenesis, metanephros development, multicellular organismal development, negative regulation of apoptotic process, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of cell differentiation, negative regulation of fibroblast growth factor receptor signaling pathway, negative regulation of gene expression, negative regulation of male gonad development, negative regulation of steroid biosynthetic process, negative regulation of testicular blood vessel morphogenesis, negative regulation of testosterone biosynthetic process, negative regulation of transcription, DNA-dependent, non-canonical Wnt receptor signaling pathway, non-canonical Wnt receptor signaling pathway via MAPK cascade, oocyte development, paramesonephric duct development, positive regulation of aldosterone biosynthetic process, positive regulation of bone mineralization, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of collagen biosynthetic process, positive regulation of cortisol biosynthetic process, positive regulation of dermatome development, positive regulation of meiosis, positive regulation of osteoblast differentiation, positive regulation of transcription, DNA-dependent, protein palmitoylation, regulation of cell-cell adhesion, renal vesicle formation, renal vesicle induction, smooth muscle cell differentiation, somatotropin secreting cell differentiation, tertiary branching involved in mammary gland duct morphogenesis, thyroid-stimulating hormone-secreting cell differentiation Golgi apparatus, cell surface, cytoplasm, extracellular region, extracellular space, plasma membrane, proteinaceous extracellular matrix G-protein coupled receptor binding, extracellular matrix structural constituent, frizzled binding, receptor agonist activity, receptor binding, transcription corepressor activity Human WNT5A BHF-UCL UniProtKB {GO:0032755=PMID:18174455, GO:0003700=PMID:19847889, GO:0044212=PMID:19847889, GO:0051216=GO_REF:0000037, GO:0071300=GO_REF:0000024, GO:0048706=PMID:19918918, GO:0046330=GO_REF:0000033, GO:0048843=GO_REF:0000019, GO:0071560=PMID:15040835, GO:0005110=GO_REF:0000033, GO:0005115=PMID:18287027, GO:0005615=PMID:20034610, GO:0005109=PMID:18174455, GO:0060541=GO_REF:0000033, GO:0048850=GO_REF:0000019, GO:0016055=PMID:20034610, GO:0048018=PMID:18174455, GO:0051964=GO_REF:0000019, GO:0009986=GO_REF:0000019, GO:0070245=GO_REF:0000033, GO:0003323=GO_REF:0000033, GO:0007275=GO_REF:0000038, GO:0005125=GO_REF:0000019, GO:0010595=PMID:17986384, GO:0060638=GO_REF:0000019, GO:0042060=PMID:19878652, GO:0060340=PMID:19399181, GO:0045080=PMID:19520808, GO:0045732=PMID:12952940, GO:0060065=GO_REF:0000033, GO:0060067=GO_REF:0000033, GO:0060068=GO_REF:0000033, GO:0001837=PMID:12841867, GO:0048146=PMID:19251946, GO:0060599=GO_REF:0000033, GO:0000187=PMID:20034610, GO:0033138=GO_REF:0000019, GO:0051092=PMID:18287027, GO:0090037=PMID:19099253, GO:0002088=PMID:16258938, GO:0050718=PMID:18174455, GO:0030182=GO_REF:0000024, GO:0071277=PMID:18703641, GO:0060070=GO_REF:0000019, GO:0060071=GO_REF:0000033, GO:0060744=GO_REF:0000033, GO:0050919=GO_REF:0000019, GO:0005578=GO_REF:0000039, GO:0005102=GO_REF:0000002, GO:0036342=GO_REF:0000019, GO:0003344=GO_REF:0000033, GO:0030216=PMID:19399181, GO:0007494=GO_REF:0000019, GO:0060324=PMID:19918918, GO:0050729=PMID:18174455, GO:0040037=GO_REF:0000033, GO:0007442=GO_REF:0000019, GO:0061036=GO_REF:0000033, GO:0030825=PMID:19946729, GO:0045599=PMID:20032469, GO:0043032=PMID:18174455, GO:0001756=GO_REF:0000033, GO:0038031=GO_REF:0000019, GO:0060750=GO_REF:0000033, GO:0050680=GO_REF:0000019, GO:2000049=GO_REF:0000019, GO:0007223=PMID:19946729, GO:0001947=GO_REF:0000033, GO:0007411=GO_REF:0000024, GO:0048806=PMID:19918918, GO:2000484=GO_REF:0000019, GO:0032729=GO_REF:0000019, GO:0021891=GO_REF:0000024, GO:0010800=GO_REF:0000019, GO:0072201=PMID:19878652, GO:0003408=PMID:16258938, GO:0060762=GO_REF:0000033, GO:0019904=GO_REF:0000019, GO:0060760=PMID:19399181, GO:0001843=GO_REF:0000033, GO:0048546=GO_REF:0000033, GO:0060686=GO_REF:0000019, GO:0071425=PMID:9787155, GO:0045836=GO_REF:0000019, GO:0071346=PMID:18174455, GO:0010976=GO_REF:0000024, GO:0045893=PMID:19847889, GO:0045892=PMID:19277043, GO:0042733=GO_REF:0000033, GO:0001736=GO_REF:0000019, GO:0005886=GO_REF:0000033, GO:0030324=GO_REF:0000019, GO:0045778=PMID:20032469, GO:0009950=GO_REF:0000033, GO:0030514=GO_REF:0000033, GO:0060029=GO_REF:0000033, GO:0061350=GO_REF:0000019, GO:0045944=PMID:18174455, GO:0032148=PMID:20034610, GO:0061354=GO_REF:0000019, GO:0060021=PMID:18413325, GO:0090103=GO_REF:0000033, GO:0008595=GO_REF:0000019, GO:0090090=PMID:12952940, GO:0043066=PMID:19251946, GO:0090009=GO_REF:0000033, GO:0001667=GO_REF:0000019, GO:0010820=PMID:19520808, GO:0090179=GO_REF:0000019, GO:0002053=GO_REF:0000033, GO:0007257=PMID:20034610, GO:0045766=PMID:17035633, GO:0071222=PMID:18174455, GO:0002741=PMID:18174455, GO:0001938=PMID:17986384, GO:0071542=GO_REF:0000033, GO:0060157=GO_REF:0000033, GO:0060907=PMID:18174455, GO:0061347=GO_REF:0000019, GO:0061348=GO_REF:0000019, GO:0061349=GO_REF:0000019, GO:0034613=PMID:19177143, GO:0008584=PMID:17848411} P41221 Protein Wnt-5a protein 20100714 {GO:0032755=IMP, GO:0003700=IMP, GO:0044212=IDA, GO:0051216=IEA, GO:0071300=ISS, GO:0048706=IMP, GO:0046330=IBA, GO:0048843=IEA, GO:0071560=IEP, GO:0005110=IBA, GO:0005115=IPI, GO:0005615=IDA, GO:0005109=IPI, GO:0060541=IBA, GO:0048850=IEA, GO:0016055=IDA, GO:0048018=IC, GO:0051964=IEA, GO:0009986=IEA, GO:0070245=IBA, GO:0003323=IBA, GO:0007275=IEA, GO:0005125=IEA, GO:0010595=IMP, GO:0060638=IEA, GO:0042060=IDA, GO:0060340=IDA, GO:0045080=IMP, GO:0045732=IGI, GO:0060065=IBA, GO:0060067=IBA, GO:0060068=IBA, GO:0001837=IEP, GO:0048146=IDA, GO:0060599=IBA, GO:0000187=IDA, GO:0033138=IEA, GO:0051092=IDA, GO:0090037=IMP, GO:0002088=ISS, GO:0050718=IMP, GO:0030182=ISS, GO:0071277=IEP, GO:0060070=IEA, GO:0060071=IBA, GO:0060744=IBA, GO:0050919=IEA, GO:0005578=IEA, GO:0005102=IEA, GO:0036342=IEA, GO:0003344=IBA, GO:0030216=IEP, GO:0007494=IEA, GO:0060324=IMP, GO:0050729=IMP, GO:0040037=IBA, GO:0007442=IEA, GO:0061036=IBA, GO:0030825=IDA, GO:0045599=IMP, GO:0043032=IMP, GO:0001756=IBA, GO:0038031=IEA, GO:0060750=IBA, GO:0050680=IEA, GO:2000049=IEA, GO:0007223=IDA, GO:0001947=IBA, GO:0007411=ISS, GO:0048806=IMP, GO:2000484=IEA, GO:0032729=IEA, GO:0021891=ISS, GO:0010800=IEA, GO:0072201=IDA, GO:0003408=ISS, GO:0060762=IBA, GO:0019904=IEA, GO:0060760=IDA, GO:0001843=IBA, GO:0048546=IBA, GO:0060686=IEA, GO:0071425=IDA, GO:0045836=IEA, GO:0071346=IEP, GO:0010976=ISS, GO:0045893=IMP, GO:0045892=IDA, GO:0042733=IBA, GO:0001736=IEA, GO:0005886=IBA, GO:0030324=IEA, GO:0045778=IMP, GO:0009950=IBA, GO:0030514=IBA, GO:0060029=IBA, GO:0061350=IEA, GO:0045944=IMP, GO:0032148=IDA, GO:0061354=IEA, GO:0060021=IMP, GO:0090103=IBA, GO:0008595=IEA, GO:0090090=IGI, GO:0043066=IDA, GO:0090009=IBA, GO:0001667=IEA, GO:0010820=IMP, GO:0090179=IEA, GO:0002053=IBA, GO:0007257=IDA, GO:0045766=IMP, GO:0071222=IEP, GO:0002741=IMP, GO:0001938=IMP, GO:0071542=IBA, GO:0060157=IBA, GO:0060907=IMP, GO:0061347=IEA, GO:0061348=IEA, GO:0061349=IEA, GO:0034613=IDA, GO:0008584=IEP} Wnt receptor signaling pathway, Wnt receptor signaling pathway, calcium modulating pathway, Wnt receptor signaling pathway, planar cell polarity pathway, activation of JUN kinase activity, activation of MAPK activity, activation of protein kinase B activity, ameboidal cell migration, anterior/posterior axis specification, embryo, axon guidance, canonical Wnt receptor signaling pathway, cartilage development, cellular protein localization, cellular response to calcium ion, cellular response to interferon-gamma, cellular response to lipopolysaccharide, cellular response to retinoic acid, cellular response to transforming growth factor beta stimulus, cervix development, cochlea morphogenesis, convergent extension involved in organogenesis, digestive tract morphogenesis, dopaminergic neuron differentiation, dorsal/ventral axis specification, embryonic digit morphogenesis, embryonic skeletal system development, epithelial cell proliferation involved in mammary gland duct elongation, epithelial to mesenchymal transition, establishment of planar polarity, face development, genitalia development, heart looping, hematopoietic stem cell proliferation, hindgut morphogenesis, hypophysis morphogenesis, keratinocyte differentiation, lateral sprouting involved in mammary gland duct morphogenesis, lens development in camera-type eye, lung development, male gonad development, mammary gland branching involved in thelarche, mesenchymal-epithelial cell signaling, midgut development, multicellular organismal development, negative chemotaxis, negative regulation of BMP signaling pathway, negative regulation of apoptotic process, negative regulation of axon extension involved in axon guidance, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of epithelial cell proliferation, negative regulation of fat cell differentiation, negative regulation of fibroblast growth factor receptor signaling pathway, negative regulation of mesenchymal cell proliferation, negative regulation of prostatic bud formation, negative regulation of synapse assembly, negative regulation of transcription, DNA-dependent, neural tube closure, neuron differentiation, non-canonical Wnt receptor signaling pathway via JNK cascade, olfactory bulb interneuron development, optic cup formation involved in camera-type eye development, palate development, pericardium morphogenesis, planar cell polarity pathway involved in cardiac muscle tissue morphogenesis, planar cell polarity pathway involved in cardiac right atrium morphogenesis, planar cell polarity pathway involved in neural tube closure, planar cell polarity pathway involved in outflow tract morphogenesis, planar cell polarity pathway involved in pericardium morphogenesis, planar cell polarity pathway involved in ventricular septum morphogenesis, positive regulation of JNK cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of T cell chemotaxis, positive regulation of angiogenesis, positive regulation of cGMP metabolic process, positive regulation of cartilage development, positive regulation of cell-cell adhesion mediated by cadherin, positive regulation of chemokine biosynthetic process, positive regulation of cytokine secretion involved in immune response, positive regulation of endothelial cell migration, positive regulation of endothelial cell proliferation, positive regulation of fibroblast proliferation, positive regulation of inflammatory response, positive regulation of interferon-gamma production, positive regulation of interleukin-1 beta secretion, positive regulation of interleukin-6 production, positive regulation of interleukin-8 secretion, positive regulation of macrophage activation, positive regulation of macrophage cytokine production, positive regulation of meiosis, positive regulation of mesenchymal cell proliferation, positive regulation of neuron projection development, positive regulation of ossification, positive regulation of peptidyl-serine phosphorylation, positive regulation of peptidyl-threonine phosphorylation, positive regulation of protein catabolic process, positive regulation of protein kinase C signaling cascade, positive regulation of response to cytokine stimulus, positive regulation of thymocyte apoptotic process, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, positive regulation of type I interferon-mediated signaling pathway, post-anal tail morphogenesis, primitive streak formation, regulation of branching involved in mammary gland duct morphogenesis, respiratory system development, somitogenesis, type B pancreatic cell development, urinary bladder development, uterus development, vagina development, wound healing cell surface, extracellular space, plasma membrane, proteinaceous extracellular matrix cytokine activity, frizzled binding, frizzled-2 binding, protein domain specific binding, receptor agonist activity, receptor binding, receptor tyrosine kinase-like orphan receptor binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding Human WNT5B BHF-UCL UniProtKB {GO:0005886=GO_REF:0000033, GO:0071300=GO_REF:0000024, GO:0070307=PMID:16258938, GO:0005110=GO_REF:0000033, GO:0009952=GO_REF:0000033, GO:0005615=PMID:15135146, GO:0009950=GO_REF:0000033, GO:0007223=GO_REF:0000033, GO:0060028=GO_REF:0000033, GO:0042074=GO_REF:0000033, GO:0060027=GO_REF:0000033, GO:0060541=GO_REF:0000033, GO:0002062=PMID:15135146, GO:0030182=GO_REF:0000024, GO:0045444=PMID:19577541, GO:0016055=PMID:15731909, GO:0090090=GO_REF:0000033, GO:0030335=PMID:19486338, GO:0009986=GO_REF:0000019, GO:0005578=GO_REF:0000039, GO:0005102=PMID:19486338, GO:0007275=GO_REF:0000038, GO:0001525=GO_REF:0000033, GO:0031018=GO_REF:0000033, GO:0045600=GO_REF:0000033} Q9H1J7 Protein Wnt-5b protein 20100708 {GO:0005886=IBA, GO:0071300=ISS, GO:0070307=ISS, GO:0005110=IBA, GO:0009952=IBA, GO:0005615=NAS, GO:0009950=IBA, GO:0007223=IBA, GO:0060028=IBA, GO:0042074=IBA, GO:0060027=IBA, GO:0060541=IBA, GO:0002062=IEP, GO:0030182=ISS, GO:0045444=NAS, GO:0016055=IDA, GO:0090090=IBA, GO:0030335=IDA, GO:0009986=IEA, GO:0005578=IEA, GO:0005102=IPI, GO:0007275=IEA, GO:0001525=IBA, GO:0031018=IBA, GO:0045600=IBA} Wnt receptor signaling pathway, Wnt receptor signaling pathway, calcium modulating pathway, angiogenesis, anterior/posterior pattern specification, cell migration involved in gastrulation, cellular response to retinoic acid, chondrocyte differentiation, convergent extension involved in axis elongation, convergent extension involved in gastrulation, dorsal/ventral axis specification, endocrine pancreas development, fat cell differentiation, lens fiber cell development, multicellular organismal development, negative regulation of canonical Wnt receptor signaling pathway, neuron differentiation, positive regulation of cell migration, positive regulation of fat cell differentiation, respiratory system development cell surface, extracellular space, plasma membrane, proteinaceous extracellular matrix frizzled-2 binding, receptor binding Human UniProtKB:Q3L255 WNT6 BHF-UCL UniProtKB {GO:0060684=GO_REF:0000019, GO:0001658=GO_REF:0000019, GO:0001664=GO_REF:0000033, GO:0009798=GO_REF:0000033, GO:0009986=GO_REF:0000019, GO:0005886=GO_REF:0000033, GO:0071300=GO_REF:0000024, GO:0070172=PMID:20113781, GO:0007267=GO_REF:0000029, GO:0005578=GO_REF:0000039, GO:0005576=GO_REF:0000029, GO:0072079=GO_REF:0000019, GO:0009952=GO_REF:0000033, GO:0005615=GO_REF:0000033, GO:0061303=PMID:16258938, GO:0010628=PMID:20113781, GO:0072080=GO_REF:0000033, GO:0030182=GO_REF:0000024, GO:0042475=PMID:20113781, GO:0048754=GO_REF:0000033, GO:0045893=GO_REF:0000019, GO:0060070=GO_REF:0000033} Q9Y6F9 Protein Wnt-6 protein 20100930 {GO:0060684=IEA, GO:0001658=IEA, GO:0001664=IBA, GO:0009798=IBA, GO:0009986=IEA, GO:0005886=IBA, GO:0071300=ISS, GO:0070172=IMP, GO:0007267=NAS, GO:0005578=IEA, GO:0005576=NAS, GO:0072079=IEA, GO:0009952=IBA, GO:0005615=IBA, GO:0061303=ISS, GO:0010628=IMP, GO:0072080=IBA, GO:0030182=ISS, GO:0042475=IMP, GO:0048754=IBA, GO:0045893=IEA, GO:0060070=IBA} anterior/posterior pattern specification, axis specification, branching involved in ureteric bud morphogenesis, branching morphogenesis of an epithelial tube, canonical Wnt receptor signaling pathway, cell-cell signaling, cellular response to retinoic acid, cornea development in camera-type eye, epithelial-mesenchymal cell signaling, nephron tubule development, nephron tubule formation, neuron differentiation, odontogenesis of dentin-containing tooth, positive regulation of gene expression, positive regulation of tooth mineralization, positive regulation of transcription, DNA-dependent cell surface, extracellular region, extracellular space, plasma membrane, proteinaceous extracellular matrix G-protein coupled receptor binding Human UniProtKB:Q3C2H6 WNT7A BHF-UCL UniProtKB {GO:0043627=GO_REF:0000019, GO:0070307=PMID:16258938, GO:0090263=GO_REF:0000033, GO:0046330=GO_REF:0000033, GO:0071560=PMID:15040835, GO:0030010=GO_REF:0000019, GO:0005615=GO_REF:0000033, GO:0005109=GO_REF:0000033, GO:0000578=PMID:16826533, GO:0002062=PMID:17202865, GO:0007548=PMID:9790192, GO:0014834=GO_REF:0000033, GO:0048018=PMID:18986540, GO:0051965=PMID:18986540, GO:0009986=GO_REF:0000019, GO:0014719=GO_REF:0000033, GO:0031133=GO_REF:0000033, GO:0005125=PMID:18986540, GO:0001501=GO_REF:0000033, GO:0050808=GO_REF:0000019, GO:0001502=PMID:17202865, GO:0045893=PMID:15802269, GO:0042733=PMID:16826533, GO:0035567=GO_REF:0000019, GO:0048103=GO_REF:0000019, GO:0021846=PMID:12843296, GO:0060065=GO_REF:0000033, GO:0005886=GO_REF:0000033, GO:0060066=GO_REF:0000019, GO:0009953=GO_REF:0000033, GO:0009952=GO_REF:0000033, GO:0048864=PMID:12843296, GO:0007269=GO_REF:0000019, GO:0021707=GO_REF:0000033, GO:0008105=GO_REF:0000019, GO:0050768=PMID:12843296, GO:0045944=PMID:12857724, GO:0035659=PMID:15802269, GO:0060021=PMID:18413325, GO:0060070=PMID:18986540, GO:0022009=GO_REF:0000033, GO:0060054=PMID:15802269, GO:0043066=GO_REF:0000019, GO:0005578=GO_REF:0000039, GO:0005102=PMID:12857724, GO:0007257=GO_REF:0000033, GO:0061038=GO_REF:0000019, GO:0035116=PMID:16826533, GO:0035115=PMID:16826533} O00755 Protein Wnt-7a protein 20100708 {GO:0043627=IEA, GO:0070307=ISS, GO:0090263=IBA, GO:0046330=IBA, GO:0071560=IEP, GO:0030010=IEA, GO:0005615=IBA, GO:0005109=IBA, GO:0000578=IMP, GO:0002062=IDA, GO:0007548=TAS, GO:0014834=IBA, GO:0048018=IDA, GO:0051965=IDA, GO:0009986=IEA, GO:0014719=IBA, GO:0031133=IBA, GO:0005125=IDA, GO:0001501=IBA, GO:0050808=IEA, GO:0001502=IDA, GO:0045893=IDA, GO:0042733=IMP, GO:0035567=IEA, GO:0048103=IEA, GO:0021846=IDA, GO:0060065=IBA, GO:0005886=IBA, GO:0060066=IEA, GO:0009953=IBA, GO:0009952=IBA, GO:0048864=IDA, GO:0007269=IEA, GO:0021707=IBA, GO:0008105=IEA, GO:0050768=IDA, GO:0045944=IDA, GO:0035659=IDA, GO:0060021=IMP, GO:0060070=IDA, GO:0022009=IBA, GO:0060054=IDA, GO:0043066=IEA, GO:0005578=IEA, GO:0005102=IPI, GO:0007257=IBA, GO:0061038=IEA, GO:0035116=IMP, GO:0035115=IMP} Wnt receptor signaling pathway involved in wound healing, spreading of epidermal cells, activation of JUN kinase activity, anterior/posterior pattern specification, asymmetric protein localization, canonical Wnt receptor signaling pathway, cartilage condensation, cell proliferation in forebrain, cellular response to transforming growth factor beta stimulus, central nervous system vasculogenesis, cerebellar granule cell differentiation, chondrocyte differentiation, dorsal/ventral pattern formation, embryonic axis specification, embryonic digit morphogenesis, embryonic forelimb morphogenesis, embryonic hindlimb morphogenesis, establishment of cell polarity, lens fiber cell development, negative regulation of apoptotic process, negative regulation of neurogenesis, neurotransmitter secretion, non-canonical Wnt receptor signaling pathway, oviduct development, palate development, positive regulation of JNK cascade, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of epithelial cell proliferation involved in wound healing, positive regulation of synapse assembly, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, regulation of axon diameter, response to estrogen stimulus, satellite cell activation, satellite cell maintenance involved in skeletal muscle regeneration, sex differentiation, skeletal system development, somatic stem cell division, stem cell development, synapse organization, uterus development, uterus morphogenesis cell surface, extracellular space, plasma membrane, proteinaceous extracellular matrix cytokine activity, frizzled binding, receptor agonist activity, receptor binding Human UniProtKB:Q9DEB8 WNT7B BHF-UCL UniProtKB {GO:0060710=GO_REF:0000024, GO:0009798=GO_REF:0000033, GO:0072236=GO_REF:0000024, GO:0070307=PMID:16258938, GO:0071300=PMID:12239632, GO:0046330=GO_REF:0000033, GO:0007409=GO_REF:0000033, GO:0005615=GO_REF:0000033, GO:0005109=GO_REF:0000033, GO:0016055=GO_REF:0000024, GO:0060033=GO_REF:0000019, GO:0072089=PMID:19734317, GO:0007275=GO_REF:0000029, GO:0072207=GO_REF:0000024, GO:0072205=GO_REF:0000024, GO:0001701=GO_REF:0000024, GO:0021871=PMID:15164427, GO:0050808=GO_REF:0000024, GO:0060484=GO_REF:0000033, GO:0060535=GO_REF:0000024, GO:0060482=GO_REF:0000024, GO:0032364=GO_REF:0000024, GO:0051145=GO_REF:0000019, GO:0008284=GO_REF:0000019, GO:0060428=GO_REF:0000024, GO:0005886=GO_REF:0000033, GO:0030324=GO_REF:0000024, GO:0060425=GO_REF:0000024, GO:0072054=GO_REF:0000024, GO:0007267=GO_REF:0000029, GO:0045879=GO_REF:0000033, GO:0072053=GO_REF:0000024, GO:0009952=GO_REF:0000033, GO:0048144=PMID:19734317, GO:0060669=GO_REF:0000024, GO:0072061=GO_REF:0000024, GO:0030182=PMID:12429992, GO:0072060=GO_REF:0000024, GO:0048568=GO_REF:0000024, GO:0042476=GO_REF:0000033, GO:0042475=GO_REF:0000019, GO:0060070=GO_REF:0000024, GO:0044237=GO_REF:0000024, GO:0022009=GO_REF:0000024, GO:0061180=PMID:8168088, GO:0005102=GO_REF:0000002, GO:0005578=GO_REF:0000039, GO:0005576=GO_REF:0000029, GO:0042592=GO_REF:0000024, GO:0006917=GO_REF:0000019, GO:0007257=GO_REF:0000033, GO:0060560=GO_REF:0000024, GO:0045669=GO_REF:0000024, GO:0010628=GO_REF:0000019, GO:0003338=GO_REF:0000024, GO:0016332=GO_REF:0000024, GO:0005201=GO_REF:0000029} P56706 Protein Wnt-7b protein 20100708 {GO:0060710=ISS, GO:0009798=IBA, GO:0072236=ISS, GO:0070307=ISS, GO:0071300=IEP, GO:0046330=IBA, GO:0007409=IBA, GO:0005615=IBA, GO:0005109=IBA, GO:0016055=ISS, GO:0060033=IEA, GO:0072089=IEP, GO:0007275=NAS, GO:0072207=ISS, GO:0072205=ISS, GO:0001701=ISS, GO:0021871=IEP, GO:0050808=ISS, GO:0060484=IBA, GO:0060535=ISS, GO:0060482=ISS, GO:0032364=ISS, GO:0051145=IEA, GO:0008284=IEA, GO:0060428=ISS, GO:0005886=IBA, GO:0030324=ISS, GO:0060425=ISS, GO:0072054=ISS, GO:0007267=NAS, GO:0045879=IBA, GO:0072053=ISS, GO:0009952=IBA, GO:0048144=IEP, GO:0060669=ISS, GO:0072061=ISS, GO:0030182=IEP, GO:0072060=ISS, GO:0048568=ISS, GO:0042476=IBA, GO:0042475=IEA, GO:0060070=ISS, GO:0044237=ISS, GO:0022009=ISS, GO:0061180=IEP, GO:0005102=IEA, GO:0005578=IEA, GO:0005576=NAS, GO:0042592=ISS, GO:0006917=IEA, GO:0007257=IBA, GO:0060560=ISS, GO:0045669=ISS, GO:0010628=IEA, GO:0003338=ISS, GO:0016332=ISS, GO:0005201=NAS} Wnt receptor signaling pathway, activation of JUN kinase activity, anatomical structure regression, anterior/posterior pattern specification, axis specification, axonogenesis, canonical Wnt receptor signaling pathway, cell-cell signaling, cellular metabolic process, cellular response to retinoic acid, central nervous system vasculogenesis, chorio-allantoic fusion, developmental growth involved in morphogenesis, embryonic organ development, embryonic placenta morphogenesis, establishment or maintenance of polarity of embryonic epithelium, fibroblast proliferation, forebrain regionalization, homeostatic process, in utero embryonic development, induction of apoptosis, inner medullary collecting duct development, lens fiber cell development, lobar bronchus development, lung development, lung epithelium development, lung morphogenesis, lung-associated mesenchyme development, mammary gland epithelium development, metanephric collecting duct development, metanephric epithelium development, metanephric loop of Henle development, metanephros morphogenesis, multicellular organismal development, negative regulation of smoothened signaling pathway, neuron differentiation, odontogenesis, odontogenesis of dentin-containing tooth, outer medullary collecting duct development, oxygen homeostasis, positive regulation of JNK cascade, positive regulation of cell proliferation, positive regulation of gene expression, positive regulation of osteoblast differentiation, renal inner medulla development, renal outer medulla development, smooth muscle cell differentiation, stem cell proliferation, synapse organization, trachea cartilage morphogenesis extracellular region, extracellular space, plasma membrane, proteinaceous extracellular matrix extracellular matrix structural constituent, frizzled binding, receptor binding Human UniProtKB:Q3L254 WNT8A BHF-UCL UniProtKB {GO:0021512=GO_REF:0000033, GO:0005886=GO_REF:0000033, GO:0060896=GO_REF:0000033, GO:0001756=GO_REF:0000033, GO:0001654=GO_REF:0000033, GO:0030178=GO_REF:0000033, GO:0001710=GO_REF:0000033, GO:0009953=GO_REF:0000033, GO:0005615=GO_REF:0000024, GO:0044335=GO_REF:0000024, GO:0005109=PMID:11408932, GO:0032880=GO_REF:0000019, GO:0014034=GO_REF:0000024, GO:0042074=GO_REF:0000033, GO:0009949=GO_REF:0000033, GO:0035284=GO_REF:0000033, GO:0061317=PMID:20559569, GO:0060021=PMID:18413325, GO:0032526=PMID:11956596, GO:0016055=GO_REF:0000038, GO:0060070=PMID:11408932, GO:0048018=PMID:11408932, GO:0001664=GO_REF:0000033, GO:0045743=GO_REF:0000033, GO:0005578=GO_REF:0000024, GO:0005102=GO_REF:0000002, GO:0044324=GO_REF:0000024, GO:0007275=GO_REF:0000038, GO:0007398=GO_REF:0000033, GO:0048561=GO_REF:0000019, GO:0010085=GO_REF:0000033, GO:0007492=GO_REF:0000033, GO:0030903=GO_REF:0000033, GO:0030902=GO_REF:0000033} Q9H1J5 Protein Wnt-8a protein 20100715 {GO:0021512=IBA, GO:0005886=IBA, GO:0060896=IBA, GO:0001756=IBA, GO:0001654=IBA, GO:0030178=IBA, GO:0001710=IBA, GO:0009953=IBA, GO:0005615=ISS, GO:0044335=ISS, GO:0005109=NAS, GO:0032880=IEA, GO:0014034=ISS, GO:0042074=IBA, GO:0009949=IBA, GO:0035284=IBA, GO:0061317=IEP, GO:0060021=IMP, GO:0032526=NAS, GO:0016055=IEA, GO:0060070=NAS, GO:0048018=NAS, GO:0001664=IBA, GO:0045743=IBA, GO:0005578=ISS, GO:0005102=IEA, GO:0044324=ISS, GO:0007275=IEA, GO:0007398=IBA, GO:0048561=IEA, GO:0010085=IBA, GO:0007492=IBA, GO:0030903=IBA, GO:0030902=IBA} Wnt receptor signaling pathway, brain segmentation, canonical Wnt receptor signaling pathway, canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment, canonical Wnt receptor signaling pathway involved in neural crest cell differentiation, cell migration involved in gastrulation, dorsal/ventral pattern formation, ectoderm development, endoderm development, establishment of organ orientation, eye development, hindbrain development, mesodermal cell fate commitment, multicellular organismal development, negative regulation of Wnt receptor signaling pathway, neural crest cell fate commitment, neural plate pattern specification, notochord development, palate development, polarity specification of anterior/posterior axis, polarity specification of proximal/distal axis, positive regulation of fibroblast growth factor receptor signaling pathway, regulation of protein localization, regulation of transcription involved in anterior/posterior axis specification, response to retinoic acid, somitogenesis, spinal cord anterior/posterior patterning extracellular space, plasma membrane, proteinaceous extracellular matrix G-protein coupled receptor binding, frizzled binding, receptor agonist activity, receptor binding Human WNT9B BHF-UCL UniProtKB {GO:0001658=GO_REF:0000033, GO:0009798=GO_REF:0000033, GO:0005886=GO_REF:0000033, GO:0071300=GO_REF:0000024, GO:0007267=PMID:9441749, GO:0048704=GO_REF:0000033, GO:0009952=GO_REF:0000033, GO:0005615=GO_REF:0000033, GO:0048701=GO_REF:0000019, GO:0072181=GO_REF:0000033, GO:0030539=GO_REF:0000033, GO:0030182=GO_REF:0000024, GO:0060021=GO_REF:0000033, GO:0032526=PMID:11604992, GO:0016055=GO_REF:0000038, GO:0060070=GO_REF:0000033, GO:0060071=GO_REF:0000033, GO:0072046=GO_REF:0000033, GO:0072170=GO_REF:0000033, GO:0001664=GO_REF:0000033, GO:0009786=GO_REF:0000019, GO:0072044=GO_REF:0000033, GO:0005578=GO_REF:0000039, GO:0005102=GO_REF:0000002, GO:0005576=PMID:9441749, GO:0007275=PMID:9441749, GO:0043085=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0061303=PMID:16258938, GO:0003339=GO_REF:0000033, GO:0007492=GO_REF:0000033, GO:0061038=GO_REF:0000033, GO:0072003=GO_REF:0000033, GO:0001932=GO_REF:0000019, GO:0035150=GO_REF:0000019} O14905 Protein Wnt-9b protein 20100930 {GO:0001658=IBA, GO:0009798=IBA, GO:0005886=IBA, GO:0071300=ISS, GO:0007267=NAS, GO:0048704=IBA, GO:0009952=IBA, GO:0005615=IBA, GO:0048701=IEA, GO:0072181=IBA, GO:0030539=IBA, GO:0030182=ISS, GO:0060021=IBA, GO:0032526=NAS, GO:0016055=IEA, GO:0060070=IBA, GO:0060071=IBA, GO:0072046=IBA, GO:0072170=IBA, GO:0001664=IBA, GO:0009786=IEA, GO:0072044=IBA, GO:0005578=IEA, GO:0005102=IEA, GO:0005576=NAS, GO:0007275=NAS, GO:0043085=IEA, GO:0001701=IEA, GO:0061303=ISS, GO:0003339=IBA, GO:0007492=IBA, GO:0061038=IBA, GO:0072003=IBA, GO:0001932=IEA, GO:0035150=IEA} Wnt receptor signaling pathway, Wnt receptor signaling pathway, planar cell polarity pathway, anterior/posterior pattern specification, axis specification, branching involved in ureteric bud morphogenesis, canonical Wnt receptor signaling pathway, cell-cell signaling, cellular response to retinoic acid, collecting duct development, cornea development in camera-type eye, embryonic cranial skeleton morphogenesis, embryonic skeletal system morphogenesis, endoderm development, establishment of planar polarity involved in nephron morphogenesis, in utero embryonic development, kidney rudiment formation, male genitalia development, mesonephric duct formation, metanephric tubule development, multicellular organismal development, neuron differentiation, palate development, positive regulation of catalytic activity, regulation of asymmetric cell division, regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis, regulation of protein phosphorylation, regulation of tube size, response to retinoic acid, uterus morphogenesis extracellular region, extracellular space, plasma membrane, proteinaceous extracellular matrix G-protein coupled receptor binding, receptor binding Human UniProtKB:Q3L250 WRAP53 HPA UniProtKB {GO:0005515=PMID:19179534, GO:0005697=PMID:19179534, GO:0005737=GO_REF:0000052, GO:0015030=PMID:19179534, GO:0003723=PMID:19179534, GO:0032203=PMID:19179534, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0051973=PMID:19179534} Q9BUR4 Telomerase Cajal body protein 1 protein 20110516 {GO:0005515=IPI, GO:0005697=IDA, GO:0005737=IDA, GO:0015030=IDA, GO:0003723=IDA, GO:0032203=IMP, GO:0005730=IDA, GO:0005634=IDA, GO:0051973=IDA} positive regulation of telomerase activity, telomere formation via telomerase Cajal body, cytoplasm, nucleolus, nucleus, telomerase holoenzyme complex RNA binding, protein binding Human WRAP73 UniProtKB UniProtKB {GO:0005813=PMID:21399614, GO:0005737=GO_REF:0000039} Q9P2S5 WD repeat-containing protein WRAP73 protein 20110517 {GO:0005813=IDA, GO:0005737=IEA} centrosome, cytoplasm Human WRB HPA UniProtKB {GO:0005789=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0016021=GO_REF:0000037} O00258 Tail-anchored protein insertion receptor WRB protein 20090616 {GO:0005789=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0016021=IEA} endoplasmic reticulum membrane, integral to membrane, nucleolus, nucleus Human WRN GOC UniProtKB {GO:0005515=PMID:16030011, GO:0008408=PMID:10871373, GO:0006200=PMID:10871376, GO:0005634=GO_REF:0000052, GO:0010259=PMID:16673358, GO:0071480=PMID:21639834, GO:0032403=PMID:10783163, GO:0042803=PMID:10783163, GO:0006302=PMID:21639834, GO:0004527=PMID:12944467, GO:0004003=PMID:9288107, GO:0000723=PMID:18212065, GO:0032508=PMID:12944467, GO:0006979=PMID:17611195, GO:0016887=PMID:10871376, GO:0009267=PMID:11420665, GO:0032389=PMID:17715146, GO:0005813=PMID:17498979, GO:0043140=GO_REF:0000002, GO:0030145=PMID:16622405, GO:0000287=PMID:16622405, GO:0051345=PMID:17611195, GO:0000405=PMID:11433031, GO:0007569=PMID:18212065, GO:0000403=PMID:17715146, GO:0007568=PMID:9288107, GO:0005730=GO_REF:0000052, GO:0004386=PMID:12181313, GO:0051880=PMID:11433031, GO:0042981=PMID:9681877, GO:0006310=GO_REF:0000002, GO:0006259=PMID:16622405, GO:0003677=PMID:9288107, GO:0005524=GO_REF:0000037, GO:0032066=PMID:11420665, GO:0006974=PMID:18203716, GO:0003678=PMID:12944467, GO:0006260=PMID:12882351, GO:0010225=PMID:17563354, GO:0009378=PMID:11433031, GO:0006284=PMID:17611195, GO:0000731=PMID:17563354, GO:0005654=PMID:12944467, GO:0043138=PMID:17715146, GO:0001302=GO_REF:0000019, GO:0031297=PMID:12882351, GO:0040009=GO_REF:0000019} Q14191 Werner syndrome ATP-dependent helicase protein 20130413 {GO:0005515=IPI, GO:0008408=IDA, GO:0006200=IDA, GO:0005634=IDA, GO:0010259=IMP, GO:0071480=IDA, GO:0032403=IDA, GO:0042803=IDA, GO:0006302=IMP, GO:0004527=IDA, GO:0004003=IDA, GO:0000723=IMP, GO:0032508=IDA, GO:0006979=IDA, GO:0016887=IDA, GO:0009267=IDA, GO:0032389=IDA, GO:0005813=IDA, GO:0043140=IEA, GO:0030145=IDA, GO:0000287=IDA, GO:0051345=IDA, GO:0000405=IDA, GO:0007569=IMP, GO:0000403=IDA, GO:0007568=NAS, GO:0005730=IDA, GO:0004386=IDA, GO:0051880=IDA, GO:0042981=IGI, GO:0006310=IEA, GO:0006259=IDA, GO:0003677=IDA, GO:0005524=IEA, GO:0032066=IDA, GO:0006974=IDA, GO:0003678=IDA, GO:0006260=IMP, GO:0010225=IDA, GO:0009378=IDA, GO:0006284=IDA, GO:0000731=IDA, GO:0005654=IDA, GO:0043138=IDA, GO:0001302=IEA, GO:0031297=IMP, GO:0040009=IEA} ATP catabolic process, DNA duplex unwinding, DNA metabolic process, DNA recombination, DNA replication, DNA synthesis involved in DNA repair, aging, base-excision repair, cell aging, cellular response to gamma radiation, cellular response to starvation, double-strand break repair, multicellular organismal aging, nucleolus to nucleoplasm transport, positive regulation of hydrolase activity, regulation of apoptotic process, regulation of growth rate, replication fork processing, replicative cell aging, response to DNA damage stimulus, response to UV-C, response to oxidative stress, telomere maintenance MutLalpha complex, centrosome, nucleolus, nucleoplasm, nucleus 3'-5' DNA helicase activity, 3'-5' exonuclease activity, ATP binding, ATP-dependent 3'-5' DNA helicase activity, ATP-dependent DNA helicase activity, ATPase activity, DNA binding, DNA helicase activity, G-quadruplex DNA binding, Y-form DNA binding, bubble DNA binding, exonuclease activity, four-way junction helicase activity, helicase activity, magnesium ion binding, manganese ion binding, protein binding, protein complex binding, protein homodimerization activity Human WRNIP1 HPA UniProtKB {GO:0005515=PMID:21903422, GO:0048471=PMID:17888034, GO:0006200=PMID:15670210, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0042802=PMID:15670210, GO:0005739=GO_REF:0000052, GO:0006260=GO_REF:0000037, GO:0030174=PMID:15670210, GO:0000731=PMID:15670210, GO:0016887=PMID:15670210} Q96S55 ATPase WRNIP1 protein 20101115 {GO:0005515=IPI, GO:0048471=IDA, GO:0006200=IMP, GO:0005730=IDA, GO:0005634=IDA, GO:0003677=IEA, GO:0005524=IEA, GO:0046872=IEA, GO:0042802=IPI, GO:0005739=IDA, GO:0006260=IEA, GO:0030174=IDA, GO:0000731=IDA, GO:0016887=IMP} ATP catabolic process, DNA replication, DNA synthesis involved in DNA repair, regulation of DNA-dependent DNA replication initiation mitochondrion, nucleolus, nucleus, perinuclear region of cytoplasm ATP binding, ATPase activity, DNA binding, identical protein binding, metal ion binding, protein binding Human WSB1 IntAct UniProtKB {GO:0005515=PMID:18093972, GO:0005622=GO_REF:0000054, GO:0035556=GO_REF:0000002, GO:0008150=GO_REF:0000015, GO:0016567=GO_REF:0000041} Q9Y6I7 WD repeat and SOCS box-containing protein 1 protein 20130415 {GO:0005515=IPI, GO:0005622=IDA, GO:0035556=IEA, GO:0008150=ND, GO:0016567=IEA} biological_process, intracellular signal transduction, protein ubiquitination intracellular protein binding Human UniProtKB:Q9QZR5 WSB2 UniPathway UniProtKB {GO:0035556=GO_REF:0000002, GO:0016567=GO_REF:0000041} Q9NYS7 WD repeat and SOCS box-containing protein 2 protein 20130413 {GO:0035556=IEA, GO:0016567=IEA} intracellular signal transduction, protein ubiquitination Human UniPathway:UPA00143 WT1 BHF-UCL UniProtKB {GO:0005515=PMID:7720589, GO:0001656=GO_REF:0000019, GO:0008406=GO_REF:0000024, GO:0001657=GO_REF:0000024, GO:0030308=PMID:9553041, GO:0001658=PMID:10101119, GO:0003700=GO_REF:0000024, GO:0044212=PMID:7588596, GO:0007281=GO_REF:0000024, GO:0072075=GO_REF:0000024, GO:0007507=PMID:10101119, GO:0030539=GO_REF:0000024, GO:0072302=GO_REF:0000024, GO:0003690=GO_REF:0000019, GO:0009888=GO_REF:0000024, GO:0035802=GO_REF:0000024, GO:2000195=GO_REF:0000024, GO:0060231=GO_REF:0000024, GO:0000122=PMID:7585606, GO:0072207=PMID:7856737, GO:0060923=GO_REF:0000024, GO:0072284=PMID:10101119, GO:0060539=GO_REF:0000024, GO:0008270=PMID:15518539, GO:0070742=PMID:8119964, GO:0045893=PMID:21390327, GO:0045892=PMID:1332065, GO:0008380=GO_REF:0000024, GO:0072112=GO_REF:0000024, GO:0008285=PMID:9765217, GO:0030325=PMID:10101119, GO:0003723=GO_REF:0000037, GO:0005634=PMID:16934801, GO:0060421=GO_REF:0000024, GO:0032836=PMID:19205749, GO:0032835=PMID:10101119, GO:0007530=PMID:9815658, GO:0005737=GO_REF:0000024, GO:0071371=PMID:15961562, GO:0045944=GO_REF:0000019, GO:0030855=GO_REF:0000024, GO:0043010=GO_REF:0000024, GO:0006355=GO_REF:0000024, GO:0043066=PMID:10101119, GO:0006357=GO_REF:0000024, GO:0001822=PMID:11912180, GO:0001823=GO_REF:0000019, GO:0007356=GO_REF:0000024, GO:0005730=GO_REF:0000039, GO:0003156=GO_REF:0000024, GO:0003676=GO_REF:0000002, GO:0043565=PMID:1662794, GO:0001077=GO_REF:0000024, GO:0016607=PMID:16934801, GO:0072166=GO_REF:0000024, GO:2001076=GO_REF:0000024, GO:0061032=PMID:10101119, GO:0071320=PMID:15961562, GO:0001570=GO_REF:0000024, GO:0008584=PMID:17848411, GO:2000020=GO_REF:0000024} P19544 Wilms tumor protein protein 20110618 {GO:0005515=IPI, GO:0001656=IEA, GO:0008406=ISS, GO:0001657=ISS, GO:0030308=IDA, GO:0001658=IGI, GO:0003700=ISS, GO:0044212=IDA, GO:0007281=ISS, GO:0072075=ISS, GO:0007507=IGI, GO:0030539=ISS, GO:0072302=ISS, GO:0003690=IEA, GO:0009888=ISS, GO:0035802=ISS, GO:2000195=ISS, GO:0060231=ISS, GO:0000122=IDA, GO:0072207=IEP, GO:0060923=ISS, GO:0072284=IGI, GO:0060539=ISS, GO:0008270=IDA, GO:0070742=IPI, GO:0045893=IDA, GO:0045892=IDA, GO:0008380=ISS, GO:0072112=ISS, GO:0008285=IDA, GO:0030325=IGI, GO:0003723=IEA, GO:0005634=IDA, GO:0060421=ISS, GO:0032836=IMP, GO:0032835=IGI, GO:0007530=IDA, GO:0005737=ISS, GO:0071371=IDA, GO:0045944=IEA, GO:0030855=ISS, GO:0043010=ISS, GO:0006355=ISS, GO:0043066=IGI, GO:0006357=ISS, GO:0001822=IGI, GO:0001823=IEA, GO:0007356=ISS, GO:0005730=IEA, GO:0003156=ISS, GO:0003676=IEA, GO:0043565=IDA, GO:0001077=ISS, GO:0016607=IDA, GO:0072166=ISS, GO:2001076=ISS, GO:0061032=IGI, GO:0071320=IEP, GO:0001570=ISS, GO:0008584=IEP, GO:2000020=ISS} RNA splicing, adrenal cortex formation, adrenal gland development, branching involved in ureteric bud morphogenesis, camera-type eye development, cardiac muscle cell fate commitment, cellular response to cAMP, cellular response to gonadotropin stimulus, diaphragm development, epithelial cell differentiation, germ cell development, glomerular basement membrane development, glomerular visceral epithelial cell differentiation, glomerulus development, gonad development, heart development, kidney development, male genitalia development, male gonad development, mesenchymal to epithelial transition, mesonephros development, metanephric S-shaped body morphogenesis, metanephric epithelium development, metanephric mesenchyme development, metanephros development, negative regulation of apoptotic process, negative regulation of cell growth, negative regulation of cell proliferation, negative regulation of female gonad development, negative regulation of metanephric glomerular mesangial cell proliferation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of heart growth, positive regulation of male gonad development, positive regulation of metanephric ureteric bud development, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, posterior mesonephric tubule development, regulation of organ formation, regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, sex determination, thorax and anterior abdomen determination, tissue development, ureteric bud development, vasculogenesis, visceral serous pericardium development cytoplasm, nuclear speck, nucleolus, nucleus C2H2 zinc finger domain binding, RNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, double-stranded DNA binding, nucleic acid binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding, zinc ion binding Human UniProtKB:P22561 WTAP HPA UniProtKB {GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0031965=PMID:10942595, GO:0007049=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0005654=GO_REF:0000019} Q15007 Pre-mRNA-splicing regulator WTAP protein 20101115 {GO:0008380=IEA, GO:0006397=IEA, GO:0031965=IDA, GO:0007049=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0005654=IEA} RNA splicing, cell cycle, mRNA processing nuclear membrane, nucleolus, nucleoplasm, nucleus NOT Human WTIP InterPro UniProtKB {GO:0005515=PMID:22286099, GO:0001666=PMID:22286099, GO:0006355=GO_REF:0000037, GO:0003714=GO_REF:0000019, GO:2000637=PMID:20616046, GO:0005634=GO_REF:0000039, GO:0006351=GO_REF:0000037, GO:0035331=PMID:20303269, GO:0005912=GO_REF:0000039, GO:0000932=PMID:20616046, GO:0035195=PMID:20616046, GO:0007010=PMID:21834987, GO:0022604=PMID:21834987, GO:0008270=GO_REF:0000002} K7ENH9 Wilms tumor protein 1-interacting protein protein 20130413 {GO:0005515=IPI, GO:0001666=IDA, GO:0006355=IEA, GO:0003714=IEA, GO:2000637=IMP, GO:0005634=IEA, GO:0006351=IEA, GO:0035331=IDA, GO:0005912=IEA, GO:0000932=IDA, GO:0035195=IMP, GO:0007010=IMP, GO:0022604=IMP, GO:0008270=IEA} cytoskeleton organization, gene silencing by miRNA, negative regulation of hippo signaling cascade, positive regulation of gene silencing by miRNA, regulation of cell morphogenesis, regulation of transcription, DNA-dependent, response to hypoxia, transcription, DNA-dependent adherens junction, cytoplasmic mRNA processing body, nucleus protein binding, transcription corepressor activity, zinc ion binding Human InterPro:IPR001781 WWC1 HPA UniProtKB {GO:0005515=PMID:16684779, GO:0006355=GO_REF:0000037, GO:0048471=PMID:18596123, GO:0005794=GO_REF:0000052, GO:0003713=PMID:16684779, GO:0005634=PMID:16684779, GO:0032587=PMID:18190796, GO:0035329=Reactome:REACT_118607, GO:0006351=GO_REF:0000037, GO:0005829=Reactome:REACT_118857, GO:0035330=PMID:20159598, GO:0043234=GO_REF:0000019, GO:0005737=PMID:16684779, GO:0016477=PMID:18596123, GO:0030674=GO_REF:0000019, GO:0043410=PMID:18190796} Q8IX03 Protein KIBRA protein 20110516 {GO:0005515=IPI, GO:0006355=IEA, GO:0048471=IDA, GO:0005794=IDA, GO:0003713=IDA, GO:0005634=IDA, GO:0032587=IDA, GO:0035329=TAS, GO:0006351=IEA, GO:0005829=TAS, GO:0035330=IMP, GO:0043234=IEA, GO:0005737=IDA, GO:0016477=IDA, GO:0030674=IEA, GO:0043410=IDA} cell migration, hippo signaling cascade, positive regulation of MAPK cascade, regulation of hippo signaling cascade, regulation of transcription, DNA-dependent, transcription, DNA-dependent Golgi apparatus, cytoplasm, cytosol, nucleus, perinuclear region of cytoplasm, protein complex, ruffle membrane protein binding, protein binding, bridging, transcription coactivator activity Human WWC2 null null {} null null null null {} null null null WWC3 null null {} null null null null {} null null null WWOX BHF-UCL UniProtKB {GO:0005515=PMID:15064722, GO:0050662=PMID:10786676, GO:0048037=PMID:10786676, GO:0043065=GO_REF:0000024, GO:0005794=PMID:15064722, GO:0005886=PMID:19366691, GO:0030178=PMID:19465938, GO:0071560=PMID:19366691, GO:0048705=GO_REF:0000024, GO:0006915=GO_REF:0000037, GO:0005634=PMID:19366691, GO:0006917=GO_REF:0000024, GO:0001649=GO_REF:0000019, GO:0005829=PMID:19366691, GO:0005739=GO_REF:0000024, GO:0005902=PMID:19366691, GO:0005737=PMID:19465938, GO:0045944=GO_REF:0000024, GO:0016491=PMID:10786676, GO:0046983=PMID:10786676, GO:0019899=PMID:19366691, GO:0016055=GO_REF:0000037, GO:0008202=PMID:10786676, GO:0055114=PMID:10786676} Q9NZC7 WW domain-containing oxidoreductase protein 20111214 {GO:0005515=IPI, GO:0050662=TAS, GO:0048037=TAS, GO:0043065=ISS, GO:0005794=IDA, GO:0005886=IDA, GO:0030178=IDA, GO:0071560=IDA, GO:0048705=ISS, GO:0006915=IEA, GO:0005634=IDA, GO:0006917=ISS, GO:0001649=IEA, GO:0005829=IDA, GO:0005739=ISS, GO:0005902=IDA, GO:0005737=IDA, GO:0045944=ISS, GO:0016491=TAS, GO:0046983=TAS, GO:0019899=IPI, GO:0016055=IEA, GO:0008202=TAS, GO:0055114=TAS} Wnt receptor signaling pathway, apoptotic process, cellular response to transforming growth factor beta stimulus, induction of apoptosis, negative regulation of Wnt receptor signaling pathway, osteoblast differentiation, oxidation-reduction process, positive regulation of apoptotic process, positive regulation of transcription from RNA polymerase II promoter, skeletal system morphogenesis, steroid metabolic process Golgi apparatus, cytoplasm, cytosol, microvillus, mitochondrion, nucleus, plasma membrane coenzyme binding, cofactor binding, enzyme binding, oxidoreductase activity, protein binding, protein dimerization activity Human WWP1 IntAct UniProtKB {GO:0005515=PMID:19447967, GO:0004842=Reactome:REACT_160256, GO:0016567=PMID:12535537, GO:0005886=GO_REF:0000039, GO:0000151=PMID:9169421, GO:0005634=GO_REF:0000033, GO:0007417=PMID:9647693, GO:0046718=PMID:12450395, GO:0055085=Reactome:REACT_15518, GO:0005829=Reactome:REACT_160256, GO:0005622=GO_REF:0000002, GO:0007165=PMID:9169421, GO:0005737=GO_REF:0000033, GO:0034220=Reactome:REACT_25300, GO:0042787=GO_REF:0000033, GO:0043161=GO_REF:0000019, GO:0045892=GO_REF:0000024} Q9H0M0 NEDD4-like E3 ubiquitin-protein ligase WWP1 protein 20130415 {GO:0005515=IPI, GO:0004842=TAS, GO:0016567=TAS, GO:0005886=IEA, GO:0000151=NAS, GO:0005634=IBA, GO:0007417=NAS, GO:0046718=TAS, GO:0055085=TAS, GO:0005829=TAS, GO:0005622=IEA, GO:0007165=NAS, GO:0005737=IBA, GO:0034220=TAS, GO:0042787=IBA, GO:0043161=IEA, GO:0045892=ISS} central nervous system development, ion transmembrane transport, negative regulation of transcription, DNA-dependent, proteasomal ubiquitin-dependent protein catabolic process, protein ubiquitination, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, signal transduction, transmembrane transport, viral entry into host cell cytoplasm, cytosol, intracellular, nucleus, plasma membrane, ubiquitin ligase complex protein binding, ubiquitin-protein ligase activity Human UniProtKB:Q16630 WWP2 BHF-UCL UniProtKB {GO:0005515=PMID:21258410, GO:0004842=PMID:19651900, GO:0016567=PMID:18776082, GO:0032410=PMID:18776082, GO:0000151=PMID:9647693, GO:0005634=PMID:19274063, GO:0000122=PMID:15047715, GO:0051224=PMID:18776082, GO:0046718=PMID:12450395, GO:0043433=PMID:15047715, GO:1901016=PMID:17289006, GO:0005737=PMID:15047715, GO:0070534=GO_REF:0000024, GO:0042787=GO_REF:0000033, GO:0042391=PMID:17289006, GO:0010629=PMID:18776082, GO:0001085=PMID:15047715, GO:0034765=PMID:17289006, GO:0043161=PMID:19274063, GO:0045892=PMID:15047715, GO:0006464=PMID:9169421, GO:0008134=PMID:19651900} O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 protein 20120801 {GO:0005515=IPI, GO:0004842=IDA, GO:0016567=IDA, GO:0032410=IDA, GO:0000151=TAS, GO:0005634=IDA, GO:0000122=ISS, GO:0051224=IMP, GO:0046718=TAS, GO:0043433=ISS, GO:1901016=IDA, GO:0005737=ISS, GO:0070534=ISS, GO:0042787=IBA, GO:0042391=IDA, GO:0010629=IMP, GO:0001085=ISS, GO:0034765=IDA, GO:0043161=IMP, GO:0045892=ISS, GO:0006464=TAS, GO:0008134=IPI} cellular protein modification process, negative regulation of gene expression, negative regulation of protein transport, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, negative regulation of transporter activity, proteasomal ubiquitin-dependent protein catabolic process, protein K63-linked ubiquitination, protein ubiquitination, protein ubiquitination involved in ubiquitin-dependent protein catabolic process, regulation of ion transmembrane transport, regulation of membrane potential, regulation of potassium ion transmembrane transporter activity, viral entry into host cell cytoplasm, nucleus, ubiquitin ligase complex RNA polymerase II transcription factor binding, protein binding, transcription factor binding, ubiquitin-protein ligase activity Human WWTR1 HPA UniProtKB {GO:0005515=PMID:20412773, GO:0010467=Reactome:REACT_71, GO:0008284=PMID:18227151, GO:0006367=Reactome:REACT_118713, GO:0045599=GO_REF:0000019, GO:0017145=PMID:18568018, GO:0010718=PMID:18227151, GO:0005634=GO_REF:0000052, GO:0035414=PMID:20412773, GO:0032835=GO_REF:0000019, GO:0042803=GO_REF:0000019, GO:0005829=Reactome:REACT_121368, GO:0005737=GO_REF:0000052, GO:0045944=Reactome:REACT_120734, GO:0007179=Reactome:REACT_6844, GO:0090090=PMID:20412773, GO:0005667=GO_REF:0000019, GO:0006355=PMID:11118213, GO:0003714=GO_REF:0000019, GO:0003713=PMID:19010321, GO:0005730=GO_REF:0000052, GO:0000122=GO_REF:0000019, GO:0035329=PMID:20412773, GO:0060390=PMID:18568018, GO:0001649=GO_REF:0000019, GO:0006351=Reactome:REACT_121061, GO:0060271=GO_REF:0000019, GO:0001933=PMID:20412773, GO:0005654=Reactome:REACT_121015, GO:0006469=PMID:20412773} Q9GZV5 WW domain-containing transcription regulator protein 1 protein 20080205 {GO:0005515=IPI, GO:0010467=TAS, GO:0008284=IDA, GO:0006367=TAS, GO:0045599=IEA, GO:0017145=IDA, GO:0010718=IDA, GO:0005634=IDA, GO:0035414=IMP, GO:0032835=IEA, GO:0042803=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0045944=TAS, GO:0007179=TAS, GO:0090090=IMP, GO:0005667=IEA, GO:0006355=NAS, GO:0003714=IEA, GO:0003713=IDA, GO:0005730=IDA, GO:0000122=IEA, GO:0035329=IDA, GO:0060390=IDA, GO:0001649=IEA, GO:0006351=TAS, GO:0060271=IEA, GO:0001933=IMP, GO:0005654=TAS, GO:0006469=IMP} cilium morphogenesis, gene expression, glomerulus development, hippo signaling cascade, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of catenin import into nucleus, negative regulation of fat cell differentiation, negative regulation of protein kinase activity, negative regulation of protein phosphorylation, negative regulation of transcription from RNA polymerase II promoter, osteoblast differentiation, positive regulation of cell proliferation, positive regulation of epithelial to mesenchymal transition, positive regulation of transcription from RNA polymerase II promoter, regulation of SMAD protein import into nucleus, regulation of transcription, DNA-dependent, stem cell division, transcription initiation from RNA polymerase II promoter, transcription, DNA-dependent, transforming growth factor beta receptor signaling pathway cytoplasm, cytosol, nucleolus, nucleoplasm, nucleus, transcription factor complex protein binding, protein homodimerization activity, transcription coactivator activity, transcription corepressor activity Human XAB2 IntAct UniProtKB {GO:0005515=PMID:10944529, GO:0005622=GO_REF:0000002, GO:0006396=GO_REF:0000002, GO:0006281=Reactome:REACT_216, GO:0000398=PMID:11991638, GO:0006283=Reactome:REACT_1628, GO:0001824=GO_REF:0000019, GO:0005654=Reactome:REACT_1584, GO:0005634=PMID:10944529, GO:0006289=Reactome:REACT_1826, GO:0071013=PMID:11991638, GO:0006351=PMID:10944529} Q9HCS7 Pre-mRNA-splicing factor SYF1 protein 20130415 {GO:0005515=IPI, GO:0005622=IEA, GO:0006396=IEA, GO:0006281=TAS, GO:0000398=IC, GO:0006283=TAS, GO:0001824=IEA, GO:0005654=TAS, GO:0005634=IC, GO:0006289=TAS, GO:0071013=IDA, GO:0006351=IDA} DNA repair, RNA processing, blastocyst development, mRNA splicing, via spliceosome, nucleotide-excision repair, transcription, DNA-dependent, transcription-coupled nucleotide-excision repair catalytic step 2 spliceosome, intracellular, nucleoplasm, nucleus protein binding Human UniProtKB:Q13216 XAF1 BHF-UCL UniProtKB {GO:0005739=GO_REF:0000039, GO:0060337=Reactome:REACT_25162, GO:0035456=PMID:18035482, GO:0019221=Reactome:REACT_25229, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0005829=Reactome:REACT_25192} Q6GPH4 XIAP-associated factor 1 protein 20121126 {GO:0005739=IEA, GO:0060337=TAS, GO:0035456=IDA, GO:0019221=TAS, GO:0006915=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0005829=TAS} apoptotic process, cytokine-mediated signaling pathway, response to interferon-beta, type I interferon-mediated signaling pathway cytosol, mitochondrion, nucleus zinc ion binding Human XAGE1A null null {} null null null null {} null null null XAGE1C null null {} null null null null {} null null null XAGE1D null null {} null null null null {} null null null XAGE2 null null {} null null null null {} null null null XAGE3 IntAct UniProtKB {GO:0005515=PMID:23275563} Q8WTP9 X antigen family member 3 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:P42858 XBP1 LIFEdb UniProtKB {GO:0060691=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0006366=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0005634=GO_REF:0000054, GO:0060096=GO_REF:0000019, GO:0003677=PMID:1718857, GO:0030968=Reactome:REACT_18356, GO:0043565=GO_REF:0000019, GO:0006955=PMID:1718857, GO:0031017=GO_REF:0000019, GO:0051602=GO_REF:0000019, GO:0005654=Reactome:REACT_115803, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015} P17861 X-box-binding protein 1 protein 20100607 {GO:0060691=IEA, GO:0003700=IEA, GO:0006366=IEA, GO:0042493=IEA, GO:0005634=IDA, GO:0060096=IEA, GO:0003677=TAS, GO:0030968=TAS, GO:0043565=IEA, GO:0006955=TAS, GO:0031017=IEA, GO:0051602=IEA, GO:0005654=TAS, GO:0006987=TAS, GO:0044267=TAS} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, epithelial cell maturation involved in salivary gland development, exocrine pancreas development, immune response, response to drug, response to electrical stimulus, serotonin secretion, neurotransmission, transcription from RNA polymerase II promoter nucleoplasm, nucleus DNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity Human XCL1 BHF-UCL UniProtKB {GO:2000553=GO_REF:0000024, GO:2000538=GO_REF:0000024, GO:0032733=PMID:18832695, GO:2000556=GO_REF:0000024, GO:2000518=PMID:10887101, GO:0007267=PMID:7602097, GO:0071560=GO_REF:0000024, GO:2000558=GO_REF:0000024, GO:2000412=GO_REF:0000024, GO:2000513=PMID:18832695, GO:0005615=GO_REF:0000024, GO:0043433=PMID:10887101, GO:0042803=PMID:11889129, GO:0071636=PMID:18832695, GO:0006955=GO_REF:0000002, GO:0002826=PMID:10887101, GO:0071353=GO_REF:0000024, GO:0032689=PMID:10887101, GO:0051281=PMID:7602097, GO:0032703=PMID:10887101, GO:2000562=PMID:10887101, GO:0008009=PMID:7602097, GO:0051209=GO_REF:0000024, GO:2000563=GO_REF:0000024, GO:2000566=PMID:10887101, GO:0030593=PMID:11889129, GO:0010820=PMID:7602097, GO:0050727=PMID:18832695, GO:0002725=PMID:10887101, GO:0005576=Reactome:REACT_22436, GO:0042379=PMID:9632725, GO:0002726=GO_REF:0000024, GO:0009615=PMID:14734774, GO:0071663=PMID:18832695, GO:0002690=GO_REF:0000024, GO:0007165=PMID:9632725, GO:0001916=PMID:18832695, GO:0090023=GO_REF:0000024, GO:0035782=PMID:9029087, GO:0045892=PMID:10887101, GO:2000503=PMID:9029087} P47992 Lymphotactin protein 20110314 {GO:2000553=ISS, GO:2000538=ISS, GO:0032733=IDA, GO:2000556=ISS, GO:2000518=IDA, GO:0007267=IDA, GO:0071560=ISS, GO:2000558=ISS, GO:2000412=ISS, GO:2000513=IDA, GO:0005615=ISS, GO:0043433=IDA, GO:0042803=IDA, GO:0071636=IDA, GO:0006955=IEA, GO:0002826=IC, GO:0071353=ISS, GO:0032689=IDA, GO:0051281=IDA, GO:0032703=IDA, GO:2000562=IDA, GO:0008009=IDA, GO:0051209=ISS, GO:2000563=ISS, GO:2000566=IDA, GO:0030593=TAS, GO:0010820=IDA, GO:0050727=IDA, GO:0002725=IDA, GO:0005576=TAS, GO:0042379=IDA, GO:0002726=ISS, GO:0009615=IDA, GO:0071663=IDA, GO:0002690=ISS, GO:0007165=IC, GO:0001916=IDA, GO:0090023=ISS, GO:0035782=IDA, GO:0045892=IDA, GO:2000503=IDA} cell-cell signaling, cellular response to interleukin-4, cellular response to transforming growth factor beta stimulus, immune response, mature natural killer cell chemotaxis, negative regulation of CD4-positive, alpha-beta T cell proliferation, negative regulation of T cell cytokine production, negative regulation of T-helper 1 cell activation, negative regulation of T-helper 1 type immune response, negative regulation of interferon-gamma production, negative regulation of interleukin-2 production, negative regulation of sequence-specific DNA binding transcription factor activity, negative regulation of transcription, DNA-dependent, neutrophil chemotaxis, positive regulation of B cell chemotaxis, positive regulation of CD4-positive, alpha-beta T cell proliferation, positive regulation of CD8-positive, alpha-beta T cell proliferation, positive regulation of T cell chemotaxis, positive regulation of T cell cytokine production, positive regulation of T cell mediated cytotoxicity, positive regulation of T-helper 1 cell cytokine production, positive regulation of T-helper 2 cell cytokine production, positive regulation of granzyme A production, positive regulation of granzyme B production, positive regulation of immunoglobulin production in mucosal tissue, positive regulation of interleukin-10 production, positive regulation of leukocyte chemotaxis, positive regulation of natural killer cell chemotaxis, positive regulation of neutrophil chemotaxis, positive regulation of release of sequestered calcium ion into cytosol, positive regulation of thymocyte migration, positive regulation of transforming growth factor beta production, regulation of inflammatory response, release of sequestered calcium ion into cytosol, response to virus, signal transduction extracellular region, extracellular space chemokine activity, chemokine receptor binding, protein homodimerization activity Human XCL2 Reactome UniProtKB {GO:0007165=PMID:7875320, GO:0008009=GO_REF:0000002, GO:0006955=GO_REF:0000002, GO:0006935=GO_REF:0000037, GO:0008015=PMID:7875320, GO:0005576=Reactome:REACT_22436, GO:0005615=GO_REF:0000037} Q9UBD3 Cytokine SCM-1 beta protein 20080717 {GO:0007165=TAS, GO:0008009=IEA, GO:0006955=IEA, GO:0006935=IEA, GO:0008015=TAS, GO:0005576=TAS, GO:0005615=IEA} blood circulation, chemotaxis, immune response, signal transduction extracellular region, extracellular space chemokine activity Human XCR1 ENSEMBL UniProtKB {GO:0070098=PMID:10679309, GO:0006954=PMID:9632725, GO:0051209=GO_REF:0000019, GO:0005886=Reactome:REACT_22436, GO:0007186=PMID:10679309, GO:0006935=GO_REF:0000019, GO:0007187=PMID:9632725, GO:0005887=PMID:9632725, GO:0004950=GO_REF:0000002, GO:0034097=GO_REF:0000019, GO:0007204=PMID:9632725} Q689E2 Chemokine C motif receptor 1 protein 20130413 {GO:0070098=TAS, GO:0006954=TAS, GO:0051209=IEA, GO:0005886=TAS, GO:0007186=TAS, GO:0006935=IEA, GO:0007187=TAS, GO:0005887=TAS, GO:0004950=IEA, GO:0034097=IEA, GO:0007204=TAS} G-protein coupled receptor signaling pathway, G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, chemokine-mediated signaling pathway, chemotaxis, elevation of cytosolic calcium ion concentration, inflammatory response, release of sequestered calcium ion into cytosol, response to cytokine stimulus integral to plasma membrane, plasma membrane chemokine receptor activity Human Ensembl:ENSMUSP00000077813 XDH Reactome UniProtKB {GO:0051898=PMID:18386220, GO:0008762=GO_REF:0000002, GO:2001213=PMID:18386220, GO:0005506=GO_REF:0000002, GO:0004854=PMID:8670112, GO:0051537=PMID:17301077, GO:0004855=Reactome:REACT_624, GO:0050660=PMID:17301077, GO:0009055=GO_REF:0000002, GO:0055086=Reactome:REACT_1698, GO:0005576=GO_REF:0000039, GO:0044281=Reactome:REACT_111217, GO:1900747=PMID:18386220, GO:0042803=PMID:17301077, GO:0005829=Reactome:REACT_624, GO:0043546=PMID:17301077, GO:0006195=Reactome:REACT_2086, GO:1900745=PMID:18386220, GO:0007595=GO_REF:0000019, GO:0006144=Reactome:REACT_522, GO:0001937=PMID:18386220, GO:0009115=PMID:8670112, GO:0045602=PMID:18386220, GO:0005777=GO_REF:0000039} P47989 Xanthine dehydrogenase/oxidase protein 20130213 {GO:0051898=IDA, GO:0008762=IEA, GO:2001213=IDA, GO:0005506=IEA, GO:0004854=IDA, GO:0051537=IDA, GO:0004855=EXP, GO:0050660=IDA, GO:0009055=IEA, GO:0055086=TAS, GO:0005576=IEA, GO:0044281=TAS, GO:1900747=IDA, GO:0042803=IPI, GO:0005829=TAS, GO:0043546=IDA, GO:0006195=TAS, GO:1900745=IDA, GO:0007595=IEA, GO:0006144=TAS, GO:0001937=IDA, GO:0009115=IDA, GO:0045602=IDA, GO:0005777=IEA} lactation, negative regulation of endothelial cell differentiation, negative regulation of endothelial cell proliferation, negative regulation of protein kinase B signaling cascade, negative regulation of vascular endothelial growth factor signaling pathway, negative regulation of vasculogenesis, nucleobase-containing small molecule metabolic process, positive regulation of p38MAPK cascade, purine nucleobase metabolic process, purine nucleotide catabolic process, small molecule metabolic process, xanthine catabolic process cytosol, extracellular region, peroxisome 2 iron, 2 sulfur cluster binding, UDP-N-acetylmuramate dehydrogenase activity, electron carrier activity, flavin adenine dinucleotide binding, iron ion binding, molybdopterin cofactor binding, protein homodimerization activity, xanthine dehydrogenase activity, xanthine oxidase activity Human XIAP IntAct UniProtKB {GO:0005515=PMID:21931591, GO:0043066=PMID:22173242, GO:0004842=PMID:22304967, GO:0055070=PMID:17382285, GO:0090263=PMID:22304967, GO:0050727=PMID:21447281, GO:0006915=Reactome:REACT_578, GO:0070424=PMID:20888210, GO:0005634=PMID:22304967, GO:0097193=Reactome:REACT_964, GO:0006974=PMID:18049476, GO:0005829=Reactome:REACT_2102, GO:0005737=PMID:22304967, GO:0042127=PMID:18414036, GO:0045088=PMID:21447281, GO:0008270=GO_REF:0000002, GO:0030510=PMID:18414036, GO:0016055=GO_REF:0000037, GO:0043027=PMID:9230442} P98170 E3 ubiquitin-protein ligase XIAP protein 20130415 {GO:0005515=IPI, GO:0043066=IMP, GO:0004842=IDA, GO:0055070=TAS, GO:0090263=IMP, GO:0050727=TAS, GO:0006915=TAS, GO:0070424=TAS, GO:0005634=IDA, GO:0097193=TAS, GO:0006974=IEP, GO:0005829=TAS, GO:0005737=IDA, GO:0042127=TAS, GO:0045088=TAS, GO:0008270=IEA, GO:0030510=TAS, GO:0016055=IEA, GO:0043027=IDA} Wnt receptor signaling pathway, apoptotic process, copper ion homeostasis, intrinsic apoptotic signaling pathway, negative regulation of apoptotic process, positive regulation of canonical Wnt receptor signaling pathway, regulation of BMP signaling pathway, regulation of cell proliferation, regulation of inflammatory response, regulation of innate immune response, regulation of nucleotide-binding oligomerization domain containing signaling pathway, response to DNA damage stimulus cytoplasm, cytosol, nucleus cysteine-type endopeptidase inhibitor activity involved in apoptotic process, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:P57078 XIRP1 ENSEMBL UniProtKB {GO:0005916=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0042391=GO_REF:0000019, GO:0045214=GO_REF:0000019, GO:0055013=GO_REF:0000019, GO:0003779=GO_REF:0000037} Q702N8 Xin actin-binding repeat-containing protein 1 protein 20130413 {GO:0005916=IEA, GO:0008285=IEA, GO:0042391=IEA, GO:0045214=IEA, GO:0055013=IEA, GO:0003779=IEA} cardiac muscle cell development, negative regulation of cell proliferation, regulation of membrane potential, sarcomere organization fascia adherens actin binding Human Ensembl:ENSMUSP00000107262 XIRP2 ENSEMBL UniProtKB {GO:0030018=GO_REF:0000019, GO:0030054=GO_REF:0000002, GO:0030036=GO_REF:0000002, GO:0051393=GO_REF:0000019, GO:0003281=GO_REF:0000019, GO:0003779=GO_REF:0000002, GO:0055008=GO_REF:0000019, GO:0045216=GO_REF:0000019} J3KNB1 Xin actin-binding repeat-containing protein 2 protein 20130413 {GO:0030018=IEA, GO:0030054=IEA, GO:0030036=IEA, GO:0051393=IEA, GO:0003281=IEA, GO:0003779=IEA, GO:0055008=IEA, GO:0045216=IEA} actin cytoskeleton organization, cardiac muscle tissue morphogenesis, cell-cell junction organization, ventricular septum development Z disc, cell junction actin binding, alpha-actinin binding Human Ensembl:ENSMUSP00000028410 XK PINC UniProtKB {GO:0005515=PMID:7737196, GO:0005215=PMID:8004674, GO:0006810=PMID:8004674, GO:0006865=GO_REF:0000037, GO:0016021=PMID:9647734} P51811 Membrane transport protein XK protein 20030904 {GO:0005515=IPI, GO:0005215=TAS, GO:0006810=TAS, GO:0006865=IEA, GO:0016021=TAS} amino acid transport, transport integral to membrane protein binding, transporter activity Human XKR6 UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q5GH73 XK-related protein 6 protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 XKRY PINC UniProtKB {GO:0007338=PMID:9381176, GO:0016021=GO_REF:0000037} O14609 Testis-specific XK-related protein, Y-linked protein 20030904 {GO:0007338=TAS, GO:0016021=IEA} single fertilization integral to membrane Human XPA IntAct UniProtKB {GO:0005515=PMID:20670893, GO:0008630=GO_REF:0000019, GO:0019904=PMID:17720715, GO:0009636=GO_REF:0000019, GO:0005634=PMID:1601884, GO:0046872=GO_REF:0000037, GO:0042803=PMID:8197175, GO:0003684=GO_REF:0000002, GO:0006281=Reactome:REACT_216, GO:0000166=GO_REF:0000002, GO:0005654=Reactome:REACT_2163, GO:0006289=Reactome:REACT_1826, GO:0000718=Reactome:REACT_311, GO:0006979=GO_REF:0000019, GO:0009411=GO_REF:0000019} P23025 DNA repair protein complementing XP-A cells protein 20130415 {GO:0005515=IPI, GO:0008630=IEA, GO:0019904=IPI, GO:0009636=IEA, GO:0005634=TAS, GO:0046872=IEA, GO:0042803=IPI, GO:0003684=IEA, GO:0006281=TAS, GO:0000166=IEA, GO:0005654=TAS, GO:0006289=TAS, GO:0000718=TAS, GO:0006979=IEA, GO:0009411=IEA} DNA repair, intrinsic apoptotic signaling pathway in response to DNA damage, nucleotide-excision repair, nucleotide-excision repair, DNA damage removal, response to UV, response to oxidative stress, response to toxic substance nucleoplasm, nucleus damaged DNA binding, metal ion binding, nucleotide binding, protein binding, protein domain specific binding, protein homodimerization activity Human UniProtKB:Q96EB6 XPC IntAct UniProtKB {GO:0005515=PMID:21962512, GO:0000404=PMID:19941824, GO:0000405=PMID:19941824, GO:0031573=GO_REF:0000019, GO:0042493=GO_REF:0000019, GO:0071942=PMID:11279143, GO:0005634=PMID:18682493, GO:0003684=PMID:12509299, GO:0005737=PMID:18682493, GO:0006281=Reactome:REACT_216, GO:0003697=PMID:12509299, GO:0010224=GO_REF:0000019, GO:0000075=PMID:17088560, GO:0000715=Reactome:REACT_476, GO:0005654=Reactome:REACT_2163, GO:0006289=Reactome:REACT_1826, GO:0000718=Reactome:REACT_311} Q01831 DNA repair protein complementing XP-C cells protein 20130415 {GO:0005515=IPI, GO:0000404=TAS, GO:0000405=TAS, GO:0031573=IEA, GO:0042493=IEA, GO:0071942=IDA, GO:0005634=IDA, GO:0003684=IDA, GO:0005737=IDA, GO:0006281=TAS, GO:0003697=IDA, GO:0010224=IEA, GO:0000075=IMP, GO:0000715=TAS, GO:0005654=TAS, GO:0006289=TAS, GO:0000718=TAS} DNA repair, cell cycle checkpoint, intra-S DNA damage checkpoint, nucleotide-excision repair, nucleotide-excision repair, DNA damage recognition, nucleotide-excision repair, DNA damage removal, response to UV-B, response to drug XPC complex, cytoplasm, nucleoplasm, nucleus bubble DNA binding, damaged DNA binding, loop DNA binding, protein binding, single-stranded DNA binding Human UniProtKB:P54727 XPNPEP1 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0030145=PMID:18515364, GO:0016787=GO_REF:0000002, GO:0009987=GO_REF:0000002, GO:0004177=PMID:11106490, GO:0070006=PMID:18515364, GO:0006508=PMID:11106490, GO:0010815=PMID:18515364, GO:0042803=PMID:18515364, GO:0046872=GO_REF:0000038, GO:0005829=GO_REF:0000019} Q9NQW7 Xaa-Pro aminopeptidase 1 protein 20111111 {GO:0005737=IDA, GO:0030145=IDA, GO:0016787=IEA, GO:0009987=IEA, GO:0004177=IDA, GO:0070006=IDA, GO:0006508=IDA, GO:0010815=IDA, GO:0042803=IPI, GO:0046872=IEA, GO:0005829=IEA} bradykinin catabolic process, cellular process, proteolysis cytoplasm, cytosol aminopeptidase activity, hydrolase activity, manganese ion binding, metal ion binding, metalloaminopeptidase activity, protein homodimerization activity Human XPNPEP3 MGI UniProtKB {GO:0005739=PMID:20179356, GO:0030145=GO_REF:0000002, GO:0016485=PMID:20179356, GO:0003094=PMID:20179356, GO:0009987=GO_REF:0000002, GO:0004177=PMID:20179356, GO:0006508=GO_REF:0000037, GO:0008237=GO_REF:0000037} Q9NQH7 Probable Xaa-Pro aminopeptidase 3 protein 20121022 {GO:0005739=IDA, GO:0030145=IEA, GO:0016485=IMP, GO:0003094=IMP, GO:0009987=IEA, GO:0004177=IMP, GO:0006508=IEA, GO:0008237=IEA} cellular process, glomerular filtration, protein processing, proteolysis mitochondrion aminopeptidase activity, manganese ion binding, metallopeptidase activity Human XPO1 IntAct UniProtKB {GO:0005515=PMID:16319068, GO:0022415=Reactome:REACT_6361, GO:0010467=Reactome:REACT_71, GO:0005215=Reactome:REACT_121294, GO:0000236=Reactome:REACT_682, GO:0034504=GO_REF:0000019, GO:0015030=GO_REF:0000039, GO:0003723=GO_REF:0000037, GO:0019058=Reactome:REACT_6167, GO:0005634=GO_REF:0000019, GO:0005635=PMID:9368044, GO:0006886=GO_REF:0000002, GO:0005829=Reactome:REACT_150414, GO:0005737=PMID:9368044, GO:0005643=GO_REF:0000002, GO:0005642=PMID:12210765, GO:0006611=GO_REF:0000019, GO:0000087=Reactome:REACT_910, GO:0016032=Reactome:REACT_6256, GO:0007179=Reactome:REACT_120850, GO:0030512=Reactome:REACT_120727, GO:0046825=GO_REF:0000019, GO:0016070=Reactome:REACT_21257, GO:0042176=GO_REF:0000019, GO:0016071=Reactome:REACT_20605, GO:0042493=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0005730=GO_REF:0000039, GO:0010824=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0030529=PMID:18809582, GO:0008565=GO_REF:0000019, GO:0000776=PMID:17363900, GO:0005654=Reactome:REACT_121294, GO:0051028=GO_REF:0000037, GO:0000278=Reactome:REACT_152, GO:0075733=Reactome:REACT_6296, GO:0000090=Reactome:REACT_1275} O14980 Exportin-1 protein 20130415 {GO:0005515=IPI, GO:0022415=TAS, GO:0010467=TAS, GO:0005215=TAS, GO:0000236=TAS, GO:0034504=IEA, GO:0015030=IEA, GO:0003723=IEA, GO:0019058=TAS, GO:0005634=IEA, GO:0005635=TAS, GO:0006886=IEA, GO:0005829=TAS, GO:0005737=TAS, GO:0005643=IEA, GO:0005642=IDA, GO:0006611=IEA, GO:0000087=TAS, GO:0016032=TAS, GO:0007179=TAS, GO:0030512=TAS, GO:0046825=IEA, GO:0016070=TAS, GO:0042176=IEA, GO:0016071=TAS, GO:0042493=IEA, GO:0019904=IEA, GO:0005730=IEA, GO:0010824=IEA, GO:0000122=IEA, GO:0030529=IDA, GO:0008565=IEA, GO:0000776=IDA, GO:0005654=TAS, GO:0051028=IEA, GO:0000278=TAS, GO:0075733=TAS, GO:0000090=TAS} M phase of mitotic cell cycle, RNA metabolic process, gene expression, intracellular protein transport, intracellular transport of viral material, mRNA metabolic process, mRNA transport, mitotic anaphase, mitotic cell cycle, mitotic prometaphase, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transforming growth factor beta receptor signaling pathway, protein export from nucleus, protein localization to nucleus, regulation of centrosome duplication, regulation of protein catabolic process, regulation of protein export from nucleus, response to drug, transforming growth factor beta receptor signaling pathway, viral infectious cycle, viral reproduction, viral reproductive process Cajal body, annulate lamellae, cytoplasm, cytosol, kinetochore, nuclear envelope, nuclear pore, nucleolus, nucleoplasm, nucleus, ribonucleoprotein complex RNA binding, protein binding, protein domain specific binding, protein transporter activity, transporter activity Human UniProtKB:P35232 XPO4 BHF-UCL UniProtKB {GO:0046827=PMID:16449645, GO:0005515=PMID:15282309, GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0015031=GO_REF:0000037} Q9C0E2 Exportin-4 protein 20111214 {GO:0046827=IMP, GO:0005515=IPI, GO:0005737=IEA, GO:0005634=IEA, GO:0015031=IEA} positive regulation of protein export from nucleus, protein transport cytoplasm, nucleus protein binding Human XPO5 HPA UniProtKB {GO:0005515=PMID:19124606, GO:0010467=Reactome:REACT_71, GO:0000049=GO_REF:0000019, GO:0003723=Reactome:REACT_12458, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0031047=GO_REF:0000037, GO:0005829=Reactome:REACT_12608, GO:0005737=GO_REF:0000052, GO:0005643=GO_REF:0000002, GO:0006611=GO_REF:0000019, GO:0008565=GO_REF:0000019, GO:0005654=Reactome:REACT_12608} Q9HAV4 Exportin-5 protein 20100326 {GO:0005515=IPI, GO:0010467=TAS, GO:0000049=IEA, GO:0003723=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0031047=IEA, GO:0005829=TAS, GO:0005737=IDA, GO:0005643=IEA, GO:0006611=IEA, GO:0008565=IEA, GO:0005654=TAS} gene expression, gene silencing by RNA, protein export from nucleus cytoplasm, cytosol, nuclear pore, nucleolus, nucleoplasm, nucleus RNA binding, protein binding, protein transporter activity, tRNA binding Human XPO6 HPA UniProtKB {GO:0005515=PMID:14592989, GO:0005737=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0005643=GO_REF:0000002, GO:0006611=PMID:14592989, GO:0008565=PMID:14592989, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006886=GO_REF:0000002} Q96QU8 Exportin-6 protein 20110516 {GO:0005515=IPI, GO:0005737=IDA, GO:0005886=IDA, GO:0005643=IEA, GO:0006611=IDA, GO:0008565=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0006886=IEA} intracellular protein transport, protein export from nucleus cytoplasm, nuclear pore, nucleolus, nucleus, plasma membrane protein binding, protein transporter activity Human XPO7 UniProtKB UniProtKB {GO:0005737=PMID:11071879, GO:0005643=PMID:11024021, GO:0006611=PMID:11024021, GO:0008565=GO_REF:0000002, GO:0005049=PMID:11024021, GO:0005634=PMID:11071879, GO:0051028=GO_REF:0000037, GO:0006886=GO_REF:0000002} Q9UIA9 Exportin-7 protein 20030317 {GO:0005737=IDA, GO:0005643=IDA, GO:0006611=IDA, GO:0008565=IEA, GO:0005049=IDA, GO:0005634=IDA, GO:0051028=IEA, GO:0006886=IEA} intracellular protein transport, mRNA transport, protein export from nucleus cytoplasm, nuclear pore, nucleus nuclear export signal receptor activity, protein transporter activity Human XPOT UniProtKB UniProtKB {GO:0005737=PMID:9660920, GO:0000049=PMID:9660920, GO:0006409=PMID:9660920, GO:0005643=PMID:9660920, GO:0008565=GO_REF:0000002, GO:0005654=PMID:9660920, GO:0006886=GO_REF:0000002} O43592 Exportin-T protein 20090309 {GO:0005737=IDA, GO:0000049=IDA, GO:0006409=IDA, GO:0005643=IDA, GO:0008565=IEA, GO:0005654=IDA, GO:0006886=IEA} intracellular protein transport, tRNA export from nucleus cytoplasm, nuclear pore, nucleoplasm protein transporter activity, tRNA binding Human XPR1 PINC UniProtKB {GO:0007186=PMID:9990033, GO:0005886=PMID:9927670, GO:0005887=PMID:9927670, GO:0004930=PMID:9990033, GO:0004872=PMID:9988277, GO:0009615=GO_REF:0000019, GO:0004888=PMID:9927670} Q9UBH6 Xenotropic and polytropic retrovirus receptor 1 protein 20030904 {GO:0007186=TAS, GO:0005886=TAS, GO:0005887=TAS, GO:0004930=TAS, GO:0004872=TAS, GO:0009615=IEA, GO:0004888=TAS} G-protein coupled receptor signaling pathway, response to virus integral to plasma membrane, plasma membrane G-protein coupled receptor activity, receptor activity, transmembrane signaling receptor activity Human XRCC1 HPA UniProtKB {GO:0005515=PMID:15044383, GO:0003684=GO_REF:0000002, GO:0021766=GO_REF:0000019, GO:0001666=GO_REF:0000019, GO:0000012=GO_REF:0000002, GO:0006281=Reactome:REACT_216, GO:0010033=GO_REF:0000019, GO:0006284=Reactome:REACT_1104, GO:0042493=GO_REF:0000019, GO:0005654=Reactome:REACT_1659, GO:0005634=GO_REF:0000052} P18887 DNA repair protein XRCC1 protein 20120912 {GO:0005515=IPI, GO:0003684=IEA, GO:0021766=IEA, GO:0001666=IEA, GO:0000012=IEA, GO:0006281=TAS, GO:0010033=IEA, GO:0006284=TAS, GO:0042493=IEA, GO:0005654=TAS, GO:0005634=IDA} DNA repair, base-excision repair, hippocampus development, response to drug, response to hypoxia, response to organic substance, single strand break repair nucleoplasm, nucleus damaged DNA binding, protein binding Human XRCC2 BHF-UCL UniProtKB {GO:0043524=GO_REF:0000019, GO:0006281=PMID:10422536, GO:0007126=PMID:9628903, GO:0010165=GO_REF:0000019, GO:0050769=GO_REF:0000019, GO:0000724=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0010332=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000002, GO:0008094=GO_REF:0000002} O43543 DNA repair protein XRCC2 protein 20100120 {GO:0043524=IEA, GO:0006281=IGI, GO:0007126=TAS, GO:0010165=IEA, GO:0050769=IEA, GO:0000724=IEA, GO:0005634=IEA, GO:0010332=IEA, GO:0001701=IEA, GO:0003677=IEA, GO:0005524=IEA, GO:0008094=IEA} DNA repair, double-strand break repair via homologous recombination, in utero embryonic development, meiosis, negative regulation of neuron apoptotic process, positive regulation of neurogenesis, response to X-ray, response to gamma radiation nucleus ATP binding, DNA binding, DNA-dependent ATPase activity Human XRCC3 BHF-UCL UniProtKB {GO:0005515=PMID:21965664, GO:0048471=PMID:16215984, GO:0010033=GO_REF:0000019, GO:0006310=GO_REF:0000037, GO:0005634=PMID:16215984, GO:0006259=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0005524=GO_REF:0000037, GO:0006974=PMID:7603995, GO:0005739=PMID:20413593, GO:0005737=PMID:16215984, GO:0006281=PMID:10422536, GO:0008094=GO_REF:0000002} O43542 DNA repair protein XRCC3 protein 20100120 {GO:0005515=IPI, GO:0048471=IDA, GO:0010033=IEA, GO:0006310=IEA, GO:0005634=IDA, GO:0006259=IEA, GO:0003677=IEA, GO:0005524=IEA, GO:0006974=TAS, GO:0005739=IDA, GO:0005737=IDA, GO:0006281=IGI, GO:0008094=IEA} DNA metabolic process, DNA recombination, DNA repair, response to DNA damage stimulus, response to organic substance cytoplasm, mitochondrion, nucleus, perinuclear region of cytoplasm ATP binding, DNA binding, DNA-dependent ATPase activity, protein binding Human XRCC4 HPA UniProtKB {GO:0005515=PMID:16439205, GO:0022415=Reactome:REACT_6266, GO:0000793=PMID:12589063, GO:0051351=PMID:9242410, GO:0010165=PMID:9242410, GO:0016874=PMID:9242410, GO:0005634=GO_REF:0000052, GO:0048146=GO_REF:0000019, GO:0006303=Reactome:REACT_1022, GO:0006302=Reactome:REACT_2054, GO:0005829=PMID:9259561, GO:0043524=GO_REF:0000019, GO:0050769=GO_REF:0000019, GO:0016032=Reactome:REACT_6256, GO:0002328=GO_REF:0000019, GO:0005958=PMID:15194694, GO:0010332=GO_REF:0000019, GO:0071285=GO_REF:0000019, GO:0033077=GO_REF:0000019, GO:0033152=GO_REF:0000019, GO:0045190=GO_REF:0000019, GO:0008022=PMID:9259651, GO:0007417=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0003677=PMID:9259561, GO:0032807=PMID:9242410, GO:0070419=PMID:20383123, GO:0006281=Reactome:REACT_216, GO:0051103=PMID:12517771, GO:0005654=Reactome:REACT_9073, GO:0075713=Reactome:REACT_6918} Q13426 DNA repair protein XRCC4 protein 20080205 {GO:0005515=IPI, GO:0022415=TAS, GO:0000793=IDA, GO:0051351=IDA, GO:0010165=IDA, GO:0016874=IDA, GO:0005634=IDA, GO:0048146=IEA, GO:0006303=TAS, GO:0006302=TAS, GO:0005829=IDA, GO:0043524=IEA, GO:0050769=IEA, GO:0016032=TAS, GO:0002328=IEA, GO:0005958=IDA, GO:0010332=IEA, GO:0071285=IEA, GO:0033077=IEA, GO:0033152=IEA, GO:0045190=IEA, GO:0008022=IPI, GO:0007417=IEA, GO:0001701=IEA, GO:0003677=IDA, GO:0032807=IDA, GO:0070419=IDA, GO:0006281=TAS, GO:0051103=IDA, GO:0005654=TAS, GO:0075713=TAS} DNA ligation involved in DNA repair, DNA repair, T cell differentiation in thymus, cellular response to lithium ion, central nervous system development, double-strand break repair, double-strand break repair via nonhomologous end joining, establishment of integrated proviral latency, immunoglobulin V(D)J recombination, in utero embryonic development, isotype switching, negative regulation of neuron apoptotic process, positive regulation of fibroblast proliferation, positive regulation of ligase activity, positive regulation of neurogenesis, pro-B cell differentiation, response to X-ray, response to gamma radiation, viral reproduction, viral reproductive process DNA ligase IV complex, DNA-dependent protein kinase-DNA ligase 4 complex, condensed chromosome, cytosol, nonhomologous end joining complex, nucleoplasm, nucleus DNA binding, ligase activity, protein C-terminus binding, protein binding Human XRCC5 HPA UniProtKB {GO:0005515=PMID:17308091, GO:0022415=Reactome:REACT_6266, GO:0044212=PMID:18809223, GO:0008283=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0006303=PMID:15824061, GO:0006302=Reactome:REACT_2054, GO:0003691=PMID:10409678, GO:0005737=GO_REF:0000019, GO:0004003=GO_REF:0000002, GO:0003690=PMID:7957065, GO:0000723=PMID:15824061, GO:0050769=GO_REF:0000019, GO:0016032=Reactome:REACT_6256, GO:0000784=PMID:10535943, GO:0031625=PMID:22266820, GO:0000783=PMID:15100233, GO:0043066=GO_REF:0000019, GO:0042162=PMID:10535943, GO:0005730=GO_REF:0000052, GO:0006310=GO_REF:0000037, GO:0060218=GO_REF:0000019, GO:0008022=PMID:10783163, GO:0005524=GO_REF:0000037, GO:0003677=PMID:1537839, GO:0006351=GO_REF:0000037, GO:0003684=GO_REF:0000002, GO:0070419=PMID:20383123, GO:0051575=PMID:20383123, GO:0043564=PMID:20383123, GO:0006281=Reactome:REACT_216, GO:0005654=Reactome:REACT_9073, GO:0045892=PMID:8621488, GO:0075713=Reactome:REACT_6918} P13010 X-ray repair cross-complementing protein 5 protein 20100326 {GO:0005515=IPI, GO:0022415=TAS, GO:0044212=IDA, GO:0008283=IEA, GO:0005634=IDA, GO:0006303=TAS, GO:0006302=TAS, GO:0003691=IDA, GO:0005737=IEA, GO:0004003=IEA, GO:0003690=TAS, GO:0000723=TAS, GO:0050769=IEA, GO:0016032=TAS, GO:0000784=IDA, GO:0031625=IPI, GO:0000783=TAS, GO:0043066=IEA, GO:0042162=IDA, GO:0005730=IDA, GO:0006310=IEA, GO:0060218=IEA, GO:0008022=IPI, GO:0005524=IEA, GO:0003677=NAS, GO:0006351=IEA, GO:0003684=IEA, GO:0070419=IDA, GO:0051575=IMP, GO:0043564=IDA, GO:0006281=TAS, GO:0005654=TAS, GO:0045892=IMP, GO:0075713=TAS} DNA recombination, DNA repair, cell proliferation, double-strand break repair, double-strand break repair via nonhomologous end joining, establishment of integrated proviral latency, hematopoietic stem cell differentiation, negative regulation of apoptotic process, negative regulation of transcription, DNA-dependent, positive regulation of neurogenesis, telomere maintenance, transcription, DNA-dependent, viral reproduction, viral reproductive process Ku70:Ku80 complex, cytoplasm, nonhomologous end joining complex, nuclear chromosome, telomeric region, nuclear telomere cap complex, nucleolus, nucleoplasm, nucleus 5'-deoxyribose-5-phosphate lyase activity, ATP binding, ATP-dependent DNA helicase activity, DNA binding, damaged DNA binding, double-stranded DNA binding, double-stranded telomeric DNA binding, protein C-terminus binding, protein binding, telomeric DNA binding, transcription regulatory region DNA binding, ubiquitin protein ligase binding NOT Human XRCC6 BHF-UCL UniProtKB {GO:0005515=PMID:10984620, GO:0022415=Reactome:REACT_6266, GO:0044212=PMID:18809223, GO:0005634=PMID:10508516, GO:0006303=PMID:15824061, GO:0006302=Reactome:REACT_2054, GO:0003691=PMID:10409678, GO:0005737=GO_REF:0000019, GO:0004003=GO_REF:0000002, GO:0003690=PMID:7957065, GO:0000723=PMID:15824061, GO:0050769=GO_REF:0000019, GO:0045944=PMID:18809223, GO:0010212=GO_REF:0000019, GO:0016032=Reactome:REACT_6256, GO:0000783=PMID:15100233, GO:0005667=PMID:12145306, GO:0033151=GO_REF:0000019, GO:0042162=GO_REF:0000002, GO:0008022=PMID:10783163, GO:0003677=PMID:1537839, GO:0005524=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0070419=PMID:20383123, GO:0051575=PMID:20383123, GO:0003684=GO_REF:0000002, GO:0043564=PMID:20383123, GO:0006281=Reactome:REACT_216, GO:0016020=PMID:2917966, GO:0005654=Reactome:REACT_9073, GO:0045893=PMID:18809223, GO:0045892=PMID:8621488, GO:0075713=Reactome:REACT_6918, GO:0006266=PMID:9826654} P12956 X-ray repair cross-complementing protein 6 protein 20081219 {GO:0005515=IPI, GO:0022415=TAS, GO:0044212=IDA, GO:0005634=TAS, GO:0006303=TAS, GO:0006302=TAS, GO:0003691=IDA, GO:0005737=IEA, GO:0004003=IEA, GO:0003690=TAS, GO:0000723=TAS, GO:0050769=IEA, GO:0045944=IMP, GO:0010212=IEA, GO:0016032=TAS, GO:0000783=TAS, GO:0005667=IDA, GO:0033151=IEA, GO:0042162=IEA, GO:0008022=IPI, GO:0003677=NAS, GO:0005524=IEA, GO:0006351=IEA, GO:0070419=IDA, GO:0051575=IMP, GO:0003684=IEA, GO:0043564=IDA, GO:0006281=TAS, GO:0016020=TAS, GO:0005654=TAS, GO:0045893=IMP, GO:0045892=IMP, GO:0075713=TAS, GO:0006266=TAS} DNA ligation, DNA repair, V(D)J recombination, double-strand break repair, double-strand break repair via nonhomologous end joining, establishment of integrated proviral latency, negative regulation of transcription, DNA-dependent, positive regulation of neurogenesis, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, response to ionizing radiation, telomere maintenance, transcription, DNA-dependent, viral reproduction, viral reproductive process Ku70:Ku80 complex, cytoplasm, membrane, nonhomologous end joining complex, nuclear telomere cap complex, nucleoplasm, nucleus, transcription factor complex 5'-deoxyribose-5-phosphate lyase activity, ATP binding, ATP-dependent DNA helicase activity, DNA binding, damaged DNA binding, double-stranded DNA binding, double-stranded telomeric DNA binding, protein C-terminus binding, protein binding, telomeric DNA binding, transcription regulatory region DNA binding Human XRCC6BP1 UniProtKB UniProtKB {GO:0004677=PMID:10219089, GO:0006508=GO_REF:0000037, GO:0005958=PMID:10219089, GO:0006303=PMID:10219089, GO:0004222=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q9Y6H3 Mitochondrial inner membrane protease ATP23 homolog protein 20010815 {GO:0004677=TAS, GO:0006508=IEA, GO:0005958=NAS, GO:0006303=TAS, GO:0004222=IEA, GO:0046872=IEA} double-strand break repair via nonhomologous end joining, proteolysis DNA-dependent protein kinase-DNA ligase 4 complex DNA-dependent protein kinase activity, metal ion binding, metalloendopeptidase activity Human XRN1 HPA UniProtKB {GO:0005515=PMID:21876179, GO:0010467=Reactome:REACT_71, GO:0016075=PMID:20368444, GO:0005794=GO_REF:0000052, GO:0008409=GO_REF:0000002, GO:0005886=GO_REF:0000052, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003723=GO_REF:0000037, GO:0071028=PMID:17545563, GO:0000956=PMID:17545563, GO:0043928=Reactome:REACT_20518, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0005829=Reactome:REACT_25297, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0004527=GO_REF:0000002, GO:0000932=GO_REF:0000019, GO:0071044=PMID:18172165, GO:0045111=GO_REF:0000052, GO:0000288=Reactome:REACT_20639} Q8IZH2 5'-3' exoribonuclease 1 protein 20101115 {GO:0005515=IPI, GO:0010467=TAS, GO:0016075=IMP, GO:0005794=IDA, GO:0008409=IEA, GO:0005886=IDA, GO:0016070=TAS, GO:0016071=TAS, GO:0003723=IEA, GO:0071028=IMP, GO:0000956=IMP, GO:0043928=TAS, GO:0003676=IEA, GO:0003677=IEA, GO:0005829=TAS, GO:0005622=IEA, GO:0005737=IDA, GO:0004527=IEA, GO:0000932=IEA, GO:0071044=IMP, GO:0045111=IDA, GO:0000288=TAS} RNA metabolic process, exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, gene expression, histone mRNA catabolic process, mRNA metabolic process, nuclear mRNA surveillance, nuclear-transcribed mRNA catabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, rRNA catabolic process Golgi apparatus, cytoplasm, cytoplasmic mRNA processing body, cytosol, intermediate filament cytoskeleton, intracellular, plasma membrane 5'-3' exonuclease activity, DNA binding, RNA binding, exonuclease activity, nucleic acid binding, protein binding Human XRN2 HPA UniProtKB {GO:0006353=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0006396=PMID:10409438, GO:0006355=GO_REF:0000037, GO:0008409=PMID:15565158, GO:0016070=GO_REF:0000024, GO:0016235=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0007283=PMID:10409438, GO:0003676=GO_REF:0000002, GO:0006401=PMID:10409438, GO:0004534=PMID:10409438, GO:0004518=PMID:10409438, GO:0016049=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0000738=PMID:15565158} Q9H0D6 5'-3' exoribonuclease 2 protein 20120912 {GO:0006353=IEA, GO:0006397=IEA, GO:0006396=TAS, GO:0006355=IEA, GO:0008409=IDA, GO:0016070=ISS, GO:0016235=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0007283=IEP, GO:0003676=IEA, GO:0006401=TAS, GO:0004534=TAS, GO:0004518=TAS, GO:0016049=ISS, GO:0008270=IEA, GO:0000738=IDA} DNA catabolic process, exonucleolytic, DNA-dependent transcription, termination, RNA catabolic process, RNA metabolic process, RNA processing, cell growth, mRNA processing, regulation of transcription, DNA-dependent, spermatogenesis aggresome, nucleolus, nucleus 5'-3' exonuclease activity, 5'-3' exoribonuclease activity, nuclease activity, nucleic acid binding, zinc ion binding Human XXYLT1 UniProtKB UniProtKB {GO:0005789=GO_REF:0000039, GO:0016763=GO_REF:0000003, GO:0016021=GO_REF:0000037} Q8NBI6 Xyloside xylosyltransferase 1 protein 20130413 {GO:0005789=IEA, GO:0016763=IEA, GO:0016021=IEA} endoplasmic reticulum membrane, integral to membrane transferase activity, transferring pentosyl groups Human UniProtKB-SubCell:SL-0097 XYLB BHF-UCL UniProtKB {GO:0005998=PMID:9763671, GO:0005997=PMID:23179721, GO:0016301=GO_REF:0000038, GO:0005975=PMID:9763671, GO:0004856=PMID:23179721, GO:0016773=GO_REF:0000002, GO:0006091=PMID:9763671, GO:0005524=GO_REF:0000037, GO:0042732=GO_REF:0000037} O75191 Xylulose kinase protein 20110401 {GO:0005998=TAS, GO:0005997=IDA, GO:0016301=IEA, GO:0005975=TAS, GO:0004856=IDA, GO:0016773=IEA, GO:0006091=TAS, GO:0005524=IEA, GO:0042732=IEA} D-xylose metabolic process, carbohydrate metabolic process, generation of precursor metabolites and energy, xylulose catabolic process, xylulose metabolic process ATP binding, kinase activity, phosphotransferase activity, alcohol group as acceptor, xylulokinase activity Human XYLT1 UniPathway UniProtKB {GO:0034605=GO_REF:0000019, GO:0008375=GO_REF:0000002, GO:0030206=GO_REF:0000041, GO:0000139=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0030158=PMID:11099377, GO:0005576=GO_REF:0000039, GO:0015012=GO_REF:0000041, GO:0016021=GO_REF:0000037, GO:0006024=PMID:11099377} Q86Y38 Xylosyltransferase 1 protein 20130413 {GO:0034605=IEA, GO:0008375=IEA, GO:0030206=IEA, GO:0000139=IEA, GO:0005789=IEA, GO:0030158=TAS, GO:0005576=IEA, GO:0015012=IEA, GO:0016021=IEA, GO:0006024=TAS} cellular response to heat, chondroitin sulfate biosynthetic process, glycosaminoglycan biosynthetic process, heparan sulfate proteoglycan biosynthetic process Golgi membrane, endoplasmic reticulum membrane, extracellular region, integral to membrane acetylglucosaminyltransferase activity, protein xylosyltransferase activity Human UniPathway:UPA00755 XYLT2 UniProtKB UniProtKB {GO:0008375=GO_REF:0000002, GO:0030206=GO_REF:0000041, GO:0000139=GO_REF:0000039, GO:0016020=GO_REF:0000002, GO:0005789=GO_REF:0000039, GO:0030158=PMID:11099377, GO:0005575=GO_REF:0000015, GO:0015012=GO_REF:0000041, GO:0016021=GO_REF:0000037, GO:0006024=PMID:11099377} Q9H1B5 Xylosyltransferase 2 protein 20061026 {GO:0008375=IEA, GO:0030206=IEA, GO:0000139=IEA, GO:0016020=IEA, GO:0005789=IEA, GO:0030158=NAS, GO:0005575=ND, GO:0015012=IEA, GO:0016021=IEA, GO:0006024=NAS} chondroitin sulfate biosynthetic process, glycosaminoglycan biosynthetic process, heparan sulfate proteoglycan biosynthetic process Golgi membrane, cellular_component, endoplasmic reticulum membrane, integral to membrane, membrane acetylglucosaminyltransferase activity, protein xylosyltransferase activity Human YAE1D1 null null {} null null null null {} null null null YAF2 HPA UniProtKB {GO:0005515=PMID:9016636, GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0003714=PMID:12706874, GO:0003713=PMID:11593398, GO:0005730=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0045893=PMID:11593398, GO:0045892=PMID:12706874, GO:0006351=GO_REF:0000037} Q8IY57 YY1-associated factor 2 protein 20101115 {GO:0005515=IPI, GO:0005622=IEA, GO:0005737=IDA, GO:0003714=IDA, GO:0003713=IDA, GO:0005730=IDA, GO:0008270=IEA, GO:0005634=IDA, GO:0045893=IDA, GO:0045892=IDA, GO:0006351=IEA} negative regulation of transcription, DNA-dependent, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, intracellular, nucleolus, nucleus protein binding, transcription coactivator activity, transcription corepressor activity, zinc ion binding Human YAP1 BHF-UCL UniProtKB {GO:0005515=PMID:9305852, GO:0010467=Reactome:REACT_71, GO:0008284=GO_REF:0000019, GO:0006367=Reactome:REACT_118713, GO:0044212=PMID:18280240, GO:0008283=PMID:17974916, GO:0010837=GO_REF:0000019, GO:0090263=GO_REF:0000019, GO:0060242=PMID:17974916, GO:0005634=PMID:18158288, GO:0071480=PMID:18280240, GO:0005829=Reactome:REACT_118829, GO:0003143=GO_REF:0000019, GO:0005737=PMID:18158288, GO:0030857=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0035019=GO_REF:0000019, GO:0070064=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0043066=GO_REF:0000019, GO:0048339=GO_REF:0000019, GO:0046622=GO_REF:0000019, GO:0003714=PMID:18158288, GO:0003713=PMID:18158288, GO:0035329=Reactome:REACT_118607, GO:0006974=PMID:18280240, GO:0048368=GO_REF:0000019, GO:0001076=GO_REF:0000019, GO:0030216=GO_REF:0000019, GO:0072091=GO_REF:0000019, GO:0003682=GO_REF:0000019, GO:0005654=Reactome:REACT_118835, GO:0030903=GO_REF:0000019, GO:0001570=GO_REF:0000019} P46937 Yorkie homolog protein 20081003 {GO:0005515=IPI, GO:0010467=TAS, GO:0008284=IEA, GO:0006367=TAS, GO:0044212=IDA, GO:0008283=IDA, GO:0010837=IEA, GO:0090263=IEA, GO:0060242=IDA, GO:0005634=IDA, GO:0071480=IDA, GO:0005829=TAS, GO:0003143=IEA, GO:0005737=IDA, GO:0030857=IEA, GO:0045944=IEA, GO:0035019=IEA, GO:0070064=IEA, GO:0005667=IEA, GO:0043066=IEA, GO:0048339=IEA, GO:0046622=IEA, GO:0003714=IDA, GO:0003713=IDA, GO:0035329=TAS, GO:0006974=IDA, GO:0048368=IEA, GO:0001076=IEA, GO:0030216=IEA, GO:0072091=IEA, GO:0003682=IEA, GO:0005654=TAS, GO:0030903=IEA, GO:0001570=IEA} cell proliferation, cellular response to gamma radiation, contact inhibition, embryonic heart tube morphogenesis, gene expression, hippo signaling cascade, keratinocyte differentiation, lateral mesoderm development, negative regulation of apoptotic process, negative regulation of epithelial cell differentiation, notochord development, paraxial mesoderm development, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of cell proliferation, positive regulation of organ growth, positive regulation of transcription from RNA polymerase II promoter, regulation of keratinocyte proliferation, regulation of stem cell proliferation, response to DNA damage stimulus, somatic stem cell maintenance, transcription initiation from RNA polymerase II promoter, vasculogenesis cytoplasm, cytosol, nucleoplasm, nucleus, transcription factor complex RNA polymerase II transcription factor binding transcription factor activity, chromatin binding, proline-rich region binding, protein binding, transcription coactivator activity, transcription corepressor activity, transcription regulatory region DNA binding Human UniProtKB:Q16621 YARS GOC UniProtKB {GO:0004831=Reactome:REACT_15492, GO:0010467=Reactome:REACT_71, GO:0000049=GO_REF:0000037, GO:0005153=PMID:10102815, GO:0006437=GO_REF:0000002, GO:0006915=PMID:10102815, GO:0005634=GO_REF:0000052, GO:0005524=GO_REF:0000037, GO:0005615=PMID:10102815, GO:0005829=Reactome:REACT_15492, GO:0006418=Reactome:REACT_15482, GO:0007165=PMID:10102815, GO:0005737=GO_REF:0000052, GO:0004871=PMID:10102815} P54577 Tyrosine--tRNA ligase, cytoplasmic protein 20130413 {GO:0004831=TAS, GO:0010467=TAS, GO:0000049=IEA, GO:0005153=TAS, GO:0006437=IEA, GO:0006915=TAS, GO:0005634=IDA, GO:0005524=IEA, GO:0005615=TAS, GO:0005829=TAS, GO:0006418=TAS, GO:0007165=NAS, GO:0005737=IDA, GO:0004871=NAS} apoptotic process, gene expression, signal transduction, tRNA aminoacylation for protein translation, tyrosyl-tRNA aminoacylation cytoplasm, cytosol, extracellular space, nucleus ATP binding, interleukin-8 receptor binding, signal transducer activity, tRNA binding, tyrosine-tRNA ligase activity Human YARS2 BHF-UCL UniProtKB {GO:0004831=PMID:15840810, GO:0010467=Reactome:REACT_71, GO:0072545=PMID:17997975, GO:0000049=PMID:20598274, GO:0070184=PMID:20598274, GO:0006437=GO_REF:0000002, GO:0005524=PMID:15779907, GO:0006412=PMID:10810093, GO:0042803=PMID:17997975, GO:0006418=Reactome:REACT_15482, GO:0005739=PMID:20598274, GO:0005737=GO_REF:0000002, GO:0005759=Reactome:REACT_15351, GO:0043039=PMID:15840810} Q9Y2Z4 Tyrosine--tRNA ligase, mitochondrial protein 20110718 {GO:0004831=IDA, GO:0010467=TAS, GO:0072545=IDA, GO:0000049=IDA, GO:0070184=IMP, GO:0006437=IEA, GO:0005524=TAS, GO:0006412=NAS, GO:0042803=IPI, GO:0006418=TAS, GO:0005739=IC, GO:0005737=IEA, GO:0005759=TAS, GO:0043039=IDA} gene expression, mitochondrial tyrosyl-tRNA aminoacylation, tRNA aminoacylation, tRNA aminoacylation for protein translation, translation, tyrosyl-tRNA aminoacylation cytoplasm, mitochondrial matrix, mitochondrion ATP binding, protein homodimerization activity, tRNA binding, tyrosine binding, tyrosine-tRNA ligase activity Human YBEY UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0006364=GO_REF:0000002, GO:0005634=PMID:22042635, GO:0004222=GO_REF:0000002, GO:0046872=GO_REF:0000037} P58557 Putative ribonuclease protein 20120618 {GO:0005739=IEA, GO:0006364=IEA, GO:0005634=IDA, GO:0004222=IEA, GO:0046872=IEA} rRNA processing mitochondrion, nucleus metal ion binding, metalloendopeptidase activity Human YBX1 HPA UniProtKB {GO:0008380=Reactome:REACT_1735, GO:0005515=PMID:19174163, GO:0010467=Reactome:REACT_71, GO:0003700=PMID:3174636, GO:0006366=PMID:3174636, GO:0010494=PMID:18335541, GO:0003723=PMID:19561594, GO:0005634=GO_REF:0000029, GO:0043231=GO_REF:0000052, GO:0005737=GO_REF:0000052, GO:0003690=PMID:1738588, GO:0003697=GO_REF:0000019, GO:0051781=GO_REF:0000037, GO:0051154=GO_REF:0000019, GO:0006355=PMID:18809583, GO:0070934=PMID:19029303, GO:0005576=GO_REF:0000039, GO:0000122=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0003677=PMID:18809583, GO:0000398=Reactome:REACT_467, GO:0030529=PMID:17289661, GO:0005654=Reactome:REACT_1935, GO:0071204=GO_REF:0000024, GO:0045892=GO_REF:0000029, GO:0005689=PMID:15146077, GO:0070937=PMID:19029303} P67809 Nuclease-sensitive element-binding protein 1 protein 20110516 {GO:0008380=TAS, GO:0005515=IPI, GO:0010467=TAS, GO:0003700=TAS, GO:0006366=TAS, GO:0010494=IDA, GO:0003723=IDA, GO:0005634=NAS, GO:0043231=IDA, GO:0005737=IDA, GO:0003690=TAS, GO:0003697=IEA, GO:0051781=IEA, GO:0051154=IEA, GO:0006355=IDA, GO:0070934=IMP, GO:0005576=IEA, GO:0000122=IEA, GO:0001701=IEA, GO:0003677=IDA, GO:0000398=TAS, GO:0030529=IDA, GO:0005654=TAS, GO:0071204=ISS, GO:0045892=NAS, GO:0005689=IDA, GO:0070937=IDA} CRD-mediated mRNA stabilization, RNA splicing, gene expression, in utero embryonic development, mRNA splicing, via spliceosome, negative regulation of striated muscle cell differentiation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of cell division, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter CRD-mediated mRNA stability complex, U12-type spliceosomal complex, cytoplasm, cytoplasmic stress granule, extracellular region, histone pre-mRNA 3'end processing complex, intracellular membrane-bounded organelle, nucleoplasm, nucleus, ribonucleoprotein complex DNA binding, RNA binding, double-stranded DNA binding, protein binding, sequence-specific DNA binding transcription factor activity, single-stranded DNA binding Human YBX2 PINC UniProtKB {GO:0017148=GO_REF:0000019, GO:0006355=GO_REF:0000002, GO:0006366=PMID:10100484, GO:0007286=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0007283=PMID:10100484, GO:0003677=GO_REF:0000037, GO:0045182=GO_REF:0000019, GO:0048599=GO_REF:0000019, GO:0008289=GO_REF:0000019, GO:0051100=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0003682=GO_REF:0000019, GO:0043021=GO_REF:0000019, GO:0009386=PMID:10100484, GO:0003730=GO_REF:0000019, GO:0048255=GO_REF:0000019, GO:0005844=GO_REF:0000019} Q9Y2T7 Y-box-binding protein 2 protein 20030904 {GO:0017148=IEA, GO:0006355=IEA, GO:0006366=TAS, GO:0007286=IEA, GO:0005634=IEA, GO:0007283=TAS, GO:0003677=IEA, GO:0045182=IEA, GO:0048599=IEA, GO:0008289=IEA, GO:0051100=IEA, GO:0005737=IEA, GO:0003682=IEA, GO:0043021=IEA, GO:0009386=TAS, GO:0003730=IEA, GO:0048255=IEA, GO:0005844=IEA} mRNA stabilization, negative regulation of binding, negative regulation of translation, oocyte development, regulation of transcription, DNA-dependent, spermatid development, spermatogenesis, transcription from RNA polymerase II promoter, translational attenuation cytoplasm, nucleus, polysome DNA binding, chromatin binding, lipid binding, mRNA 3'-UTR binding, ribonucleoprotein complex binding, translation regulator activity Human YDJC InterPro UniProtKB {GO:0016810=GO_REF:0000002, GO:0005975=GO_REF:0000002} A8MPS7 UPF0249 protein ydjC homolog protein 20130413 {GO:0016810=IEA, GO:0005975=IEA} carbohydrate metabolic process hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds Human InterPro:IPR002509 YEATS2 BHF-UCL UniProtKB {GO:0005515=PMID:18838386, GO:0072686=GO_REF:0000019, GO:0006355=GO_REF:0000002, GO:0043966=PMID:18838386, GO:0017025=PMID:18838386, GO:0005671=PMID:18838386, GO:0005634=GO_REF:0000002, GO:0000122=PMID:18838386, GO:0045892=PMID:18838386} Q9ULM3 YEATS domain-containing protein 2 protein 20101105 {GO:0005515=IPI, GO:0072686=IEA, GO:0006355=IEA, GO:0043966=IDA, GO:0017025=IPI, GO:0005671=IDA, GO:0005634=IEA, GO:0000122=IDA, GO:0045892=IDA} histone H3 acetylation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent Ada2/Gcn5/Ada3 transcription activator complex, mitotic spindle, nucleus TBP-class protein binding, protein binding Human YEATS4 HGNC UniProtKB {GO:0005515=PMID:11903063, GO:0006355=GO_REF:0000002, GO:0003700=PMID:9302258, GO:0005634=GO_REF:0000002, GO:0008022=PMID:10913114, GO:0003677=PMID:9302258, GO:0006351=GO_REF:0000037, GO:0016363=PMID:10913114, GO:0007067=PMID:10913114, GO:0043967=PMID:14966270, GO:0043968=PMID:14966270, GO:0035267=PMID:14966270, GO:0005200=PMID:10913114, GO:0005654=PMID:10913114, GO:0045893=PMID:10913114, GO:0040008=GO_REF:0000037} O95619 YEATS domain-containing protein 4 protein 20060920 {GO:0005515=IPI, GO:0006355=IEA, GO:0003700=TAS, GO:0005634=IEA, GO:0008022=IPI, GO:0003677=TAS, GO:0006351=IEA, GO:0016363=NAS, GO:0007067=NAS, GO:0043967=IDA, GO:0043968=IDA, GO:0035267=IDA, GO:0005200=NAS, GO:0005654=IDA, GO:0045893=NAS, GO:0040008=IEA} histone H2A acetylation, histone H4 acetylation, mitosis, positive regulation of transcription, DNA-dependent, regulation of growth, regulation of transcription, DNA-dependent, transcription, DNA-dependent NuA4 histone acetyltransferase complex, nuclear matrix, nucleoplasm, nucleus DNA binding, protein C-terminus binding, protein binding, sequence-specific DNA binding transcription factor activity, structural constituent of cytoskeleton Human UniProtKB:O75410 YES1 HPA UniProtKB {GO:0005154=GO_REF:0000019, GO:0005794=PMID:20605918, GO:0005815=GO_REF:0000039, GO:0005886=GO_REF:0000052, GO:0031295=Reactome:REACT_19344, GO:0050900=Reactome:REACT_12051, GO:0005524=GO_REF:0000037, GO:0044325=PMID:12538589, GO:0005829=Reactome:REACT_160304, GO:0005737=GO_REF:0000052, GO:0046777=GO_REF:0000019, GO:0015758=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0045087=Reactome:REACT_6802, GO:0043114=PMID:19267251, GO:0004713=Reactome:REACT_111112, GO:0019899=PMID:20605918, GO:0004715=PMID:19267251, GO:0038096=Reactome:REACT_160123, GO:0006464=PMID:2436037} P07947 Tyrosine-protein kinase Yes protein 20101115 {GO:0005154=IEA, GO:0005794=IDA, GO:0005815=IEA, GO:0005886=IDA, GO:0031295=TAS, GO:0050900=TAS, GO:0005524=IEA, GO:0044325=IPI, GO:0005829=TAS, GO:0005737=IDA, GO:0046777=IEA, GO:0015758=IEA, GO:0007596=TAS, GO:0045087=TAS, GO:0043114=TAS, GO:0004713=TAS, GO:0019899=IPI, GO:0004715=TAS, GO:0038096=TAS, GO:0006464=TAS} Fc-gamma receptor signaling pathway involved in phagocytosis, T cell costimulation, blood coagulation, cellular protein modification process, glucose transport, innate immune response, leukocyte migration, protein autophosphorylation, regulation of vascular permeability Golgi apparatus, cytoplasm, cytosol, microtubule organizing center, plasma membrane ATP binding, enzyme binding, epidermal growth factor receptor binding, ion channel binding, non-membrane spanning protein tyrosine kinase activity, protein tyrosine kinase activity Human YIF1A HPA UniProtKB {GO:0005515=PMID:22645275, GO:0005813=GO_REF:0000052, GO:0005793=PMID:15308636, GO:0005794=GO_REF:0000052, GO:0015031=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0030968=Reactome:REACT_18356, GO:0000139=GO_REF:0000039, GO:0005789=Reactome:REACT_115805, GO:0016021=GO_REF:0000037, GO:0016192=GO_REF:0000037, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015} O95070 Protein YIF1A protein 20101115 {GO:0005515=IPI, GO:0005813=IDA, GO:0005793=IDA, GO:0005794=IDA, GO:0015031=IEA, GO:0043231=IDA, GO:0030968=TAS, GO:0000139=IEA, GO:0005789=TAS, GO:0016021=IEA, GO:0016192=IEA, GO:0006987=TAS, GO:0044267=TAS} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, endoplasmic reticulum unfolded protein response, protein transport, vesicle-mediated transport Golgi apparatus, Golgi membrane, centrosome, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment, integral to membrane, intracellular membrane-bounded organelle protein binding Human YIF1B UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q5BJH7 Protein YIF1B protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 YIPF1 LIFEdb UniProtKB {GO:0030133=GO_REF:0000054, GO:0016020=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q9Y548 Protein YIPF1 protein 20100607 {GO:0030133=IDA, GO:0016020=IEA, GO:0016021=IEA} integral to membrane, membrane, transport vesicle Human YIPF2 LIFEdb UniProtKB {GO:0030133=GO_REF:0000054, GO:0016020=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q9BWQ6 Protein YIPF2 protein 20100607 {GO:0030133=IDA, GO:0016020=IEA, GO:0016021=IEA} integral to membrane, membrane, transport vesicle Human YIPF3 LIFEdb UniProtKB {GO:0030133=GO_REF:0000054, GO:0005794=GO_REF:0000039, GO:0005886=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0043231=GO_REF:0000052} Q9GZM5 Protein YIPF3 protein 20100607 {GO:0030133=IDA, GO:0005794=IEA, GO:0005886=IEA, GO:0016021=IEA, GO:0030154=IEA, GO:0043231=IDA} cell differentiation Golgi apparatus, integral to membrane, intracellular membrane-bounded organelle, plasma membrane, transport vesicle Human YIPF4 LIFEdb UniProtKB {GO:0005794=GO_REF:0000039, GO:0005783=GO_REF:0000054, GO:0016021=GO_REF:0000037} Q9BSR8 Protein YIPF4 protein 20100607 {GO:0005794=IEA, GO:0005783=IDA, GO:0016021=IEA} Golgi apparatus, endoplasmic reticulum, integral to membrane Human YIPF5 UniProtKB UniProtKB {GO:0030134=GO_REF:0000039, GO:0060628=GO_REF:0000019, GO:0032580=GO_REF:0000039, GO:0042175=GO_REF:0000019, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0016192=GO_REF:0000037, GO:0015031=GO_REF:0000037, GO:0070971=GO_REF:0000019} Q969M3 Protein YIPF5 protein 20130413 {GO:0030134=IEA, GO:0060628=IEA, GO:0032580=IEA, GO:0042175=IEA, GO:0005789=IEA, GO:0016021=IEA, GO:0016192=IEA, GO:0015031=IEA, GO:0070971=IEA} protein transport, regulation of ER to Golgi vesicle-mediated transport, vesicle-mediated transport ER to Golgi transport vesicle, Golgi cisterna membrane, endoplasmic reticulum exit site, endoplasmic reticulum membrane, integral to membrane, nuclear outer membrane-endoplasmic reticulum membrane network Human UniProtKB-SubCell:SL-0136 YIPF6 LIFEdb UniProtKB {GO:0016020=GO_REF:0000002, GO:0005783=GO_REF:0000054, GO:0016021=GO_REF:0000037} Q96EC8 Protein YIPF6 protein 20100607 {GO:0016020=IEA, GO:0005783=IDA, GO:0016021=IEA} endoplasmic reticulum, integral to membrane, membrane Human YKT6 HPA UniProtKB {GO:0005794=PMID:15215310, GO:0005783=PMID:9211930, GO:0031201=GO_REF:0000024, GO:0015031=GO_REF:0000037, GO:0006903=PMID:9211930, GO:0005829=GO_REF:0000039, GO:0006904=PMID:9211930, GO:0005739=GO_REF:0000052, GO:0006888=PMID:9211930, GO:0005484=PMID:15215310, GO:0005737=GO_REF:0000052, GO:0016020=GO_REF:0000038, GO:0000139=GO_REF:0000039, GO:0005887=PMID:9211930, GO:0006810=GO_REF:0000002, GO:0042147=PMID:15215310, GO:0030659=GO_REF:0000039, GO:0019706=PMID:15479160, GO:0005768=PMID:15215310} O15498 Synaptobrevin homolog YKT6 protein 20101115 {GO:0005794=IDA, GO:0005783=IDA, GO:0031201=ISS, GO:0015031=IEA, GO:0006903=IDA, GO:0005829=IEA, GO:0006904=IDA, GO:0005739=IDA, GO:0006888=IDA, GO:0005484=IDA, GO:0005737=IDA, GO:0016020=IEA, GO:0000139=IEA, GO:0005887=IDA, GO:0006810=IEA, GO:0042147=IDA, GO:0030659=IEA, GO:0019706=IDA, GO:0005768=IDA} ER to Golgi vesicle-mediated transport, protein transport, retrograde transport, endosome to Golgi, transport, vesicle docking involved in exocytosis, vesicle targeting Golgi apparatus, Golgi membrane, SNARE complex, cytoplasm, cytoplasmic vesicle membrane, cytosol, endoplasmic reticulum, endosome, integral to plasma membrane, membrane, mitochondrion SNAP receptor activity, protein-cysteine S-palmitoleyltransferase activity Human YLPM1 IntAct UniProtKB {GO:0005515=PMID:21078624, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0001078=GO_REF:0000019, GO:0016607=GO_REF:0000039, GO:0032204=GO_REF:0000019, GO:0005634=PMID:17890166} P49750 YLP motif-containing protein 1 protein 20130415 {GO:0005515=IPI, GO:0008150=ND, GO:0003674=ND, GO:0001078=IEA, GO:0016607=IEA, GO:0032204=IEA, GO:0005634=IDA} biological_process, regulation of telomere maintenance nuclear speck, nucleus RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, molecular_function, protein binding Human UniProtKB:O00555 YME1L1 UniProtKB UniProtKB {GO:0017111=GO_REF:0000002, GO:0008283=PMID:22262461, GO:0005743=PMID:22262461, GO:0006515=PMID:22262461, GO:0007005=PMID:22262461, GO:0016021=GO_REF:0000037, GO:0004222=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0046872=GO_REF:0000037} Q96TA2 ATP-dependent zinc metalloprotease YME1L1 protein 20120611 {GO:0017111=IEA, GO:0008283=IMP, GO:0005743=IDA, GO:0006515=IMP, GO:0007005=IMP, GO:0016021=IEA, GO:0004222=IEA, GO:0005524=IEA, GO:0046872=IEA} cell proliferation, misfolded or incompletely synthesized protein catabolic process, mitochondrion organization integral to membrane, mitochondrial inner membrane ATP binding, metal ion binding, metalloendopeptidase activity, nucleoside-triphosphatase activity Human YOD1 UniProtKB UniProtKB {GO:0005515=PMID:19818707, GO:0071108=PMID:19818707, GO:0006520=GO_REF:0000024, GO:0004843=PMID:19818707, GO:0070536=PMID:19818707, GO:0008270=GO_REF:0000002, GO:0030433=PMID:19818707, GO:0030968=PMID:19818707} Q5VVQ6 Ubiquitin thioesterase OTU1 protein 20091117 {GO:0005515=IPI, GO:0071108=IDA, GO:0006520=ISS, GO:0004843=IDA, GO:0070536=IDA, GO:0008270=IEA, GO:0030433=IMP, GO:0030968=IMP} ER-associated protein catabolic process, cellular amino acid metabolic process, endoplasmic reticulum unfolded protein response, protein K48-linked deubiquitination, protein K63-linked deubiquitination protein binding, ubiquitin-specific protease activity, zinc ion binding Human YPEL3 UniProtKB UniProtKB {GO:0005730=GO_REF:0000039} P61236 Protein yippee-like 3 protein 20130413 {GO:0005730=IEA} nucleolus Human UniProtKB-SubCell:SL-0188 YPEL5 null null {} null null null null {} null null null YRDC MGI UniProtKB {GO:0005739=GO_REF:0000039, GO:0003725=GO_REF:0000002, GO:0016020=GO_REF:0000039, GO:0051051=PMID:2675563} Q86U90 YrdC domain-containing protein, mitochondrial protein 20091109 {GO:0005739=IEA, GO:0003725=IEA, GO:0016020=IEA, GO:0051051=IDA} negative regulation of transport membrane, mitochondrion double-stranded RNA binding Human YTHDC1 UniProtKB UniProtKB {GO:0005515=PMID:19282290, GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0005634=GO_REF:0000039} Q96MU7 YTH domain-containing protein 1 protein 20110722 {GO:0005515=IPI, GO:0008380=IEA, GO:0006397=IEA, GO:0005634=IEA} RNA splicing, mRNA processing nucleus protein binding Human UniProtKB:P84586 YTHDC2 IntAct UniProtKB {GO:0005515=PMID:21903422, GO:0008026=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0005524=GO_REF:0000037} Q9H6S0 Probable ATP-dependent RNA helicase YTHDC2 protein 20130415 {GO:0005515=IPI, GO:0008026=IEA, GO:0003676=IEA, GO:0005524=IEA} ATP binding, ATP-dependent helicase activity, nucleic acid binding, protein binding Human UniProtKB:Q99J34 YTHDF1 null null {} null null null null {} null null null YTHDF2 PINC UniProtKB {GO:0006959=PMID:10508479} Q9Y5A9 YTH domain family protein 2 protein 20030904 {GO:0006959=TAS} humoral immune response Human YTHDF3 IntAct UniProtKB {GO:0005515=PMID:22190034} Q7Z739 YTH domain family protein 3 protein 20130415 {GO:0005515=IPI} protein binding Human UniProtKB:P04591:PRO_0000038596 YWHAB ENSEMBL UniProtKB {GO:0051219=PMID:10869435, GO:0005515=PMID:20025850, GO:0008286=Reactome:REACT_498, GO:0010467=Reactome:REACT_71, GO:0048471=PMID:12963375, GO:0042826=PMID:10869435, GO:0007264=Reactome:REACT_12077, GO:0007265=Reactome:REACT_12033, GO:0006605=GO_REF:0000019, GO:0051291=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0050815=PMID:10869435, GO:0005829=Reactome:REACT_147700, GO:0005737=GO_REF:0000019, GO:0000186=Reactome:REACT_12005, GO:1900740=Reactome:REACT_697, GO:0007173=Reactome:REACT_9417, GO:0000165=Reactome:REACT_634, GO:0007411=Reactome:REACT_18266, GO:0017053=GO_REF:0000019, GO:0030659=Reactome:REACT_147698, GO:0042470=GO_REF:0000039, GO:0048011=Reactome:REACT_11061, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0003714=GO_REF:0000019, GO:0035308=PMID:17255105, GO:0019904=GO_REF:0000019, GO:0051220=PMID:10869435, GO:0006915=Reactome:REACT_578, GO:0035329=Reactome:REACT_118607, GO:0043085=PMID:17255105, GO:0008022=GO_REF:0000019, GO:0097193=Reactome:REACT_964, GO:0008543=Reactome:REACT_9470, GO:0045087=Reactome:REACT_6802, GO:0019899=PMID:17255105, GO:0045892=GO_REF:0000019, GO:0016044=Reactome:REACT_11123} Q4VY20 14-3-3 protein beta/alpha protein 20130413 {GO:0051219=IPI, GO:0005515=IPI, GO:0008286=TAS, GO:0010467=TAS, GO:0048471=IDA, GO:0042826=IPI, GO:0007264=TAS, GO:0007265=TAS, GO:0006605=IEA, GO:0051291=IEA, GO:0032403=IEA, GO:0050815=IPI, GO:0005829=TAS, GO:0005737=IEA, GO:0000186=TAS, GO:1900740=TAS, GO:0007173=TAS, GO:0000165=TAS, GO:0007411=TAS, GO:0017053=IEA, GO:0030659=TAS, GO:0042470=IEA, GO:0048011=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0003714=IEA, GO:0035308=IDA, GO:0019904=IEA, GO:0051220=IDA, GO:0006915=TAS, GO:0035329=TAS, GO:0043085=IDA, GO:0008022=IEA, GO:0097193=TAS, GO:0008543=TAS, GO:0045087=TAS, GO:0019899=IPI, GO:0045892=IEA, GO:0016044=TAS} MAPK cascade, RNA metabolic process, Ras protein signal transduction, activation of MAPKK activity, apoptotic process, axon guidance, cellular membrane organization, cytoplasmic sequestering of protein, epidermal growth factor receptor signaling pathway, fibroblast growth factor receptor signaling pathway, gene expression, hippo signaling cascade, innate immune response, insulin receptor signaling pathway, intrinsic apoptotic signaling pathway, mRNA metabolic process, negative regulation of protein dephosphorylation, negative regulation of transcription, DNA-dependent, neurotrophin TRK receptor signaling pathway, positive regulation of catalytic activity, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, protein heterooligomerization, protein targeting, small GTPase mediated signal transduction cytoplasm, cytoplasmic vesicle membrane, cytosol, melanosome, perinuclear region of cytoplasm, transcriptional repressor complex enzyme binding, histone deacetylase binding, phosphoprotein binding, phosphoserine binding, protein C-terminus binding, protein binding, protein complex binding, protein domain specific binding, transcription corepressor activity Human Ensembl:ENSRNOP00000016981 YWHAE BHF-UCL UniProtKB {GO:0051219=PMID:10869435, GO:0005515=PMID:21988832, GO:0021987=GO_REF:0000019, GO:0042826=PMID:10869435, GO:0006605=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0050815=PMID:10869435, GO:0005829=Reactome:REACT_147700, GO:0035556=PMID:7644510, GO:0005739=GO_REF:0000019, GO:1900740=Reactome:REACT_697, GO:0000086=Reactome:REACT_2203, GO:0030659=Reactome:REACT_147698, GO:0042470=GO_REF:0000039, GO:0005871=GO_REF:0000019, GO:0048011=Reactome:REACT_13776, GO:0035308=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0006915=Reactome:REACT_13526, GO:0035329=Reactome:REACT_118607, GO:0097190=Reactome:REACT_13720, GO:0097193=Reactome:REACT_964, GO:0033267=GO_REF:0000019, GO:0021766=GO_REF:0000019, GO:0019048=GO_REF:0000037, GO:0000278=Reactome:REACT_152, GO:0001764=GO_REF:0000019, GO:0019899=PMID:10788521, GO:0016044=Reactome:REACT_11123} P62258 14-3-3 protein epsilon protein 20090803 {GO:0051219=IPI, GO:0005515=IPI, GO:0021987=IEA, GO:0042826=IPI, GO:0006605=IEA, GO:0032403=IEA, GO:0050815=IPI, GO:0005829=TAS, GO:0035556=TAS, GO:0005739=IEA, GO:1900740=TAS, GO:0000086=TAS, GO:0030659=TAS, GO:0042470=IEA, GO:0005871=IEA, GO:0048011=TAS, GO:0035308=IEA, GO:0019904=IEA, GO:0006915=TAS, GO:0035329=TAS, GO:0097190=TAS, GO:0097193=TAS, GO:0033267=IEA, GO:0021766=IEA, GO:0019048=IEA, GO:0000278=TAS, GO:0001764=IEA, GO:0019899=IPI, GO:0016044=TAS} G2/M transition of mitotic cell cycle, apoptotic process, apoptotic signaling pathway, cellular membrane organization, cerebral cortex development, hippo signaling cascade, hippocampus development, intracellular signal transduction, intrinsic apoptotic signaling pathway, mitotic cell cycle, negative regulation of protein dephosphorylation, neuron migration, neurotrophin TRK receptor signaling pathway, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, protein targeting, virus-host interaction axon part, cytoplasmic vesicle membrane, cytosol, kinesin complex, melanosome, mitochondrion enzyme binding, histone deacetylase binding, phosphoprotein binding, phosphoserine binding, protein binding, protein complex binding, protein domain specific binding Human UniProtKB:Q9UQL6 YWHAG IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0030971=GO_REF:0000019, GO:0005159=PMID:12482592, GO:0019904=GO_REF:0000019, GO:0006915=Reactome:REACT_578, GO:0006605=GO_REF:0000019, GO:0009966=PMID:10486217, GO:0097193=Reactome:REACT_964, GO:0005829=Reactome:REACT_147700, GO:1900740=Reactome:REACT_697, GO:0048167=PMID:11824616, GO:0000086=Reactome:REACT_2203, GO:0005080=PMID:10433554, GO:0045664=PMID:11824616, GO:0008426=PMID:10433554, GO:0006469=PMID:10433554, GO:0000278=Reactome:REACT_152, GO:0030659=Reactome:REACT_147698, GO:0016044=Reactome:REACT_11123} P61981 14-3-3 protein gamma protein 20130415 {GO:0005515=IPI, GO:0030971=IEA, GO:0005159=IPI, GO:0019904=IEA, GO:0006915=TAS, GO:0006605=IEA, GO:0009966=NAS, GO:0097193=TAS, GO:0005829=TAS, GO:1900740=TAS, GO:0048167=IMP, GO:0000086=TAS, GO:0005080=IPI, GO:0045664=IMP, GO:0008426=NAS, GO:0006469=NAS, GO:0000278=TAS, GO:0030659=TAS, GO:0016044=TAS} G2/M transition of mitotic cell cycle, apoptotic process, cellular membrane organization, intrinsic apoptotic signaling pathway, mitotic cell cycle, negative regulation of protein kinase activity, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, protein targeting, regulation of neuron differentiation, regulation of signal transduction, regulation of synaptic plasticity cytoplasmic vesicle membrane, cytosol insulin-like growth factor receptor binding, protein binding, protein domain specific binding, protein kinase C binding, protein kinase C inhibitor activity, receptor tyrosine kinase binding Human UniProtKB:P62258 YWHAH BHF-UCL UniProtKB {GO:0005515=PMID:20642453, GO:0006713=PMID:15790729, GO:0005159=GO_REF:0000024, GO:0019904=GO_REF:0000024, GO:0006915=Reactome:REACT_578, GO:0003779=GO_REF:0000019, GO:2000649=GO_REF:0000024, GO:0035259=PMID:9079630, GO:0006886=GO_REF:0000024, GO:0097193=Reactome:REACT_964, GO:0005829=Reactome:REACT_147700, GO:0005737=GO_REF:0000024, GO:1900740=Reactome:REACT_697, GO:0014704=PMID:16728661, GO:0048167=GO_REF:0000024, GO:0042921=PMID:15790729, GO:0002028=GO_REF:0000024, GO:0045664=GO_REF:0000024, GO:0050774=GO_REF:0000024, GO:0019899=PMID:17255105, GO:0045893=PMID:15790729, GO:0030659=Reactome:REACT_147698, GO:0016044=Reactome:REACT_11123} Q04917 14-3-3 protein eta protein 20120518 {GO:0005515=IPI, GO:0006713=IDA, GO:0005159=ISS, GO:0019904=ISS, GO:0006915=TAS, GO:0003779=IEA, GO:2000649=ISS, GO:0035259=IPI, GO:0006886=ISS, GO:0097193=TAS, GO:0005829=TAS, GO:0005737=ISS, GO:1900740=TAS, GO:0014704=IC, GO:0048167=ISS, GO:0042921=IDA, GO:0002028=ISS, GO:0045664=ISS, GO:0050774=ISS, GO:0019899=IPI, GO:0045893=IDA, GO:0030659=TAS, GO:0016044=TAS} apoptotic process, cellular membrane organization, glucocorticoid catabolic process, glucocorticoid receptor signaling pathway, intracellular protein transport, intrinsic apoptotic signaling pathway, negative regulation of dendrite morphogenesis, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, positive regulation of transcription, DNA-dependent, regulation of neuron differentiation, regulation of sodium ion transmembrane transporter activity, regulation of sodium ion transport, regulation of synaptic plasticity cytoplasm, cytoplasmic vesicle membrane, cytosol, intercalated disc actin binding, enzyme binding, glucocorticoid receptor binding, insulin-like growth factor receptor binding, protein binding, protein domain specific binding Human GO:0044325 YWHAQ BHF-UCL UniProtKB {GO:0005515=PMID:20642453, GO:0007264=GO_REF:0000019, GO:0019904=GO_REF:0000019, GO:0006915=Reactome:REACT_578, GO:0006605=GO_REF:0000019, GO:0097193=Reactome:REACT_964, GO:0005829=Reactome:REACT_147700, GO:0005737=PMID:15163635, GO:0047485=PMID:11984006, GO:1900740=Reactome:REACT_697, GO:0045892=PMID:15163635, GO:0016044=Reactome:REACT_11123, GO:0030659=Reactome:REACT_147698} P27348 14-3-3 protein theta protein 20080307 {GO:0005515=IPI, GO:0007264=IEA, GO:0019904=IEA, GO:0006915=TAS, GO:0006605=IEA, GO:0097193=TAS, GO:0005829=TAS, GO:0005737=IDA, GO:0047485=IPI, GO:1900740=TAS, GO:0045892=IDA, GO:0016044=TAS, GO:0030659=TAS} apoptotic process, cellular membrane organization, intrinsic apoptotic signaling pathway, negative regulation of transcription, DNA-dependent, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, protein targeting, small GTPase mediated signal transduction cytoplasm, cytoplasmic vesicle membrane, cytosol protein N-terminus binding, protein binding, protein domain specific binding Human YWHAZ IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0010467=Reactome:REACT_71, GO:0048471=GO_REF:0000019, GO:0006626=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0032403=GO_REF:0000019, GO:0005829=Reactome:REACT_147700, GO:0005739=GO_REF:0000019, GO:0005737=PMID:16130169, GO:1900740=Reactome:REACT_697, GO:0016301=GO_REF:0000038, GO:0031252=GO_REF:0000019, GO:0030659=Reactome:REACT_147698, GO:0010941=GO_REF:0000019, GO:0042470=GO_REF:0000039, GO:0043066=PMID:16130169, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0019904=GO_REF:0000002, GO:0030168=Reactome:REACT_798, GO:0014069=GO_REF:0000019, GO:0006915=Reactome:REACT_578, GO:0097193=Reactome:REACT_964, GO:0043234=GO_REF:0000019, GO:0007165=PMID:16130169, GO:0002553=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0005654=Reactome:REACT_25152, GO:0016044=Reactome:REACT_11123, GO:0008134=PMID:16114898} P63104 14-3-3 protein zeta/delta protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0048471=IEA, GO:0006626=IEA, GO:0005634=IEA, GO:0032403=IEA, GO:0005829=TAS, GO:0005739=IEA, GO:0005737=TAS, GO:1900740=TAS, GO:0016301=IEA, GO:0031252=IEA, GO:0030659=TAS, GO:0010941=IEA, GO:0042470=IEA, GO:0043066=TAS, GO:0016070=TAS, GO:0016071=TAS, GO:0019904=IEA, GO:0030168=TAS, GO:0014069=IEA, GO:0006915=TAS, GO:0097193=TAS, GO:0043234=IEA, GO:0007165=TAS, GO:0002553=IEA, GO:0007596=TAS, GO:0005654=TAS, GO:0016044=TAS, GO:0008134=IPI} RNA metabolic process, apoptotic process, blood coagulation, cellular membrane organization, gene expression, histamine secretion by mast cell, intrinsic apoptotic signaling pathway, mRNA metabolic process, negative regulation of apoptotic process, platelet activation, positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, protein targeting to mitochondrion, regulation of cell death, signal transduction cell leading edge, cytoplasm, cytoplasmic vesicle membrane, cytosol, melanosome, mitochondrion, nucleoplasm, nucleus, perinuclear region of cytoplasm, postsynaptic density, protein complex kinase activity, protein binding, protein complex binding, protein domain specific binding, transcription factor binding Human UniProtKB:Q9NYL2 YY1 HPA UniProtKB {GO:0005515=PMID:18026119, GO:0051276=GO_REF:0000019, GO:0003700=PMID:1946405, GO:0005886=GO_REF:0000052, GO:0044212=PMID:9857059, GO:0003723=PMID:21729784, GO:0005634=GO_REF:0000052, GO:0048593=GO_REF:0000019, GO:0007283=GO_REF:0000019, GO:0009952=GO_REF:0000019, GO:0030154=GO_REF:0000037, GO:0016363=GO_REF:0000039, GO:0034644=PMID:18026119, GO:0000724=PMID:18026119, GO:0031519=GO_REF:0000019, GO:0000400=PMID:18026119, GO:0005667=GO_REF:0000019, GO:0006357=PMID:1655281, GO:0003714=PMID:1655281, GO:0003713=PMID:1946405, GO:0000122=PMID:9857059, GO:0003676=GO_REF:0000002, GO:0034696=GO_REF:0000019, GO:0006403=GO_REF:0000019, GO:0003677=PMID:21729784, GO:0006974=PMID:18026119, GO:0001078=GO_REF:0000024, GO:0031011=PMID:21303910, GO:0010225=PMID:18026119, GO:0008270=GO_REF:0000002} P25490 Transcriptional repressor protein YY1 protein 20100326 {GO:0005515=IPI, GO:0051276=IEA, GO:0003700=TAS, GO:0005886=IDA, GO:0044212=IDA, GO:0003723=IDA, GO:0005634=IDA, GO:0048593=IEA, GO:0007283=IEA, GO:0009952=IEA, GO:0030154=IEA, GO:0016363=IEA, GO:0034644=IMP, GO:0000724=IMP, GO:0031519=IEA, GO:0000400=IDA, GO:0005667=IEA, GO:0006357=TAS, GO:0003714=TAS, GO:0003713=TAS, GO:0000122=IDA, GO:0003676=IEA, GO:0034696=IEA, GO:0006403=IEA, GO:0003677=IDA, GO:0006974=IMP, GO:0001078=ISS, GO:0031011=IDA, GO:0010225=IMP, GO:0008270=IEA} RNA localization, anterior/posterior pattern specification, camera-type eye morphogenesis, cell differentiation, cellular response to UV, chromosome organization, double-strand break repair via homologous recombination, negative regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, response to DNA damage stimulus, response to UV-C, response to prostaglandin F stimulus, spermatogenesis Ino80 complex, PcG protein complex, nuclear matrix, nucleus, plasma membrane, transcription factor complex DNA binding, RNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, four-way junction DNA binding, nucleic acid binding, protein binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, transcription corepressor activity, transcription regulatory region DNA binding, zinc ion binding Human YY1AP1 HPA UniProtKB {GO:0005515=PMID:16713569, GO:0005737=GO_REF:0000039, GO:0006355=GO_REF:0000037, GO:0051726=PMID:17541814, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0006351=GO_REF:0000037} Q9H869 YY1-associated protein 1 protein 20111111 {GO:0005515=IPI, GO:0005737=IEA, GO:0006355=IEA, GO:0051726=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0006351=IEA} regulation of cell cycle, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleolus, nucleus protein binding NOT Human YY2 HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0005886=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O15391 Transcription factor YY2 protein 20100326 {GO:0006355=IEA, GO:0005886=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus, plasma membrane DNA binding, zinc ion binding Human ZADH2 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0016491=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0005777=GO_REF:0000024} Q8N4Q0 Zinc-binding alcohol dehydrogenase domain-containing protein 2 protein 20120517 {GO:0005739=IEA, GO:0003674=ND, GO:0008150=ND, GO:0016491=IEA, GO:0008270=IEA, GO:0005777=ISS} biological_process mitochondrion, peroxisome molecular_function, oxidoreductase activity, zinc ion binding Human ZAP70 IntAct UniProtKB {GO:0005515=PMID:16461343, GO:0046638=GO_REF:0000019, GO:0050852=Reactome:REACT_12526, GO:0005886=PMID:20135127, GO:0007243=PMID:1423621, GO:0005829=Reactome:REACT_12642, GO:0050850=GO_REF:0000019, GO:0006955=PMID:1423621, GO:0005737=PMID:12359715, GO:0046777=GO_REF:0000019, GO:0042101=PMID:8176201, GO:0046641=GO_REF:0000019, GO:0045582=PMID:7630421, GO:0001772=GO_REF:0000019, GO:0043366=GO_REF:0000019, GO:0018108=PMID:22732588, GO:0005524=PMID:1423621, GO:0045059=PMID:7630421, GO:0072678=PMID:20135127, GO:0002250=PMID:20135127, GO:0042113=PMID:20135127, GO:0042110=PMID:20135127, GO:0030217=PMID:8613493, GO:0045060=GO_REF:0000019, GO:0001784=GO_REF:0000019, GO:0070489=PMID:20135127, GO:0006468=PMID:12447358, GO:0004713=Reactome:REACT_147834, GO:0004715=PMID:20135127} P43403 Tyrosine-protein kinase ZAP-70 protein 20130415 {GO:0005515=IPI, GO:0046638=IEA, GO:0050852=TAS, GO:0005886=TAS, GO:0007243=NAS, GO:0005829=TAS, GO:0050850=IEA, GO:0006955=IDA, GO:0005737=TAS, GO:0046777=IEA, GO:0042101=IDA, GO:0046641=IEA, GO:0045582=IDA, GO:0001772=IEA, GO:0043366=IEA, GO:0018108=IDA, GO:0005524=NAS, GO:0045059=IDA, GO:0072678=TAS, GO:0002250=TAS, GO:0042113=TAS, GO:0042110=TAS, GO:0030217=NAS, GO:0045060=IEA, GO:0001784=IEA, GO:0070489=TAS, GO:0006468=IDA, GO:0004713=TAS, GO:0004715=TAS} B cell activation, T cell activation, T cell aggregation, T cell differentiation, T cell migration, T cell receptor signaling pathway, adaptive immune response, beta selection, immune response, intracellular protein kinase cascade, negative thymic T cell selection, peptidyl-tyrosine phosphorylation, positive regulation of T cell differentiation, positive regulation of alpha-beta T cell differentiation, positive regulation of alpha-beta T cell proliferation, positive regulation of calcium-mediated signaling, positive thymic T cell selection, protein autophosphorylation, protein phosphorylation T cell receptor complex, cytoplasm, cytosol, immunological synapse, plasma membrane ATP binding, non-membrane spanning protein tyrosine kinase activity, phosphotyrosine binding, protein binding, protein tyrosine kinase activity Human UniProtKB:Q9Y2R2 ZBED1 PINC UniProtKB {GO:0046983=GO_REF:0000002, GO:0000228=PMID:9887332, GO:0003677=GO_REF:0000037, GO:0004803=PMID:9887332, GO:0046872=GO_REF:0000037} O96006 Zinc finger BED domain-containing protein 1 protein 20030904 {GO:0046983=IEA, GO:0000228=TAS, GO:0003677=IEA, GO:0004803=TAS, GO:0046872=IEA} nuclear chromosome DNA binding, metal ion binding, protein dimerization activity, transposase activity Human ZBED2 UniProtKB UniProtKB {GO:0003677=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q9BTP6 Zinc finger BED domain-containing protein 2 protein 20130413 {GO:0003677=IEA, GO:0046872=IEA} DNA binding, metal ion binding Human UniProtKB-KW:KW-0479 ZBED3 UniProtKB UniProtKB {GO:0016020=GO_REF:0000024, GO:0045944=GO_REF:0000024, GO:0090263=GO_REF:0000024, GO:0050821=GO_REF:0000024, GO:0001933=GO_REF:0000024, GO:0016055=GO_REF:0000037, GO:0003677=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0005829=GO_REF:0000024} Q96IU2 Zinc finger BED domain-containing protein 3 protein 20121217 {GO:0016020=ISS, GO:0045944=ISS, GO:0090263=ISS, GO:0050821=ISS, GO:0001933=ISS, GO:0016055=IEA, GO:0003677=IEA, GO:0046872=IEA, GO:0005829=ISS} Wnt receptor signaling pathway, negative regulation of protein phosphorylation, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of transcription from RNA polymerase II promoter, protein stabilization cytosol, membrane DNA binding, metal ion binding Human UniProtKB:Q9D0L1 ZBED4 HPA UniProtKB {GO:0005737=PMID:19369242, GO:0005730=GO_REF:0000052, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000002, GO:0046872=GO_REF:0000037} O75132 Zinc finger BED domain-containing protein 4 protein 20120912 {GO:0005737=IDA, GO:0005730=IDA, GO:0046983=IEA, GO:0005634=IDA, GO:0003677=IEA, GO:0046872=IEA} cytoplasm, nucleolus, nucleus DNA binding, metal ion binding, protein dimerization activity NOT Human ZBED5 UniProtKB UniProtKB {GO:0003677=GO_REF:0000002, GO:0046872=GO_REF:0000037} Q49AG3 Zinc finger BED domain-containing protein 5 protein 20130413 {GO:0003677=IEA, GO:0046872=IEA} DNA binding, metal ion binding Human UniProtKB-KW:KW-0479 ZBP1 Reactome UniProtKB {GO:0008150=GO_REF:0000015, GO:0003692=PMID:11842111, GO:0005737=PMID:19158679, GO:0003726=GO_REF:0000002, GO:0045087=Reactome:REACT_6802, GO:0003723=GO_REF:0000002, GO:0060340=GO_REF:0000019, GO:0032481=Reactome:REACT_118823, GO:0005634=PMID:19158679, GO:0003677=PMID:17618271, GO:0005829=Reactome:REACT_118851} Q9H171 Z-DNA-binding protein 1 protein 20110908 {GO:0008150=ND, GO:0003692=NAS, GO:0005737=IDA, GO:0003726=IEA, GO:0045087=TAS, GO:0003723=IEA, GO:0060340=IEA, GO:0032481=TAS, GO:0005634=IDA, GO:0003677=IDA, GO:0005829=TAS} biological_process, innate immune response, positive regulation of type I interferon production, positive regulation of type I interferon-mediated signaling pathway cytoplasm, cytosol, nucleus DNA binding, RNA binding, double-stranded RNA adenosine deaminase activity, left-handed Z-DNA binding Human ZBTB1 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9Y2K1 Zinc finger and BTB domain-containing protein 1 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZBTB10 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96DT7 Zinc finger and BTB domain-containing protein 10 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZBTB11 HPA UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O95625 Zinc finger and BTB domain-containing protein 11 protein 20090616 {GO:0008150=ND, GO:0003674=ND, GO:0006355=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} biological_process, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus, nucleus DNA binding, molecular_function, zinc ion binding NOT Human ZBTB12 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9Y330 Zinc finger and BTB domain-containing protein 12 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZBTB16 IntAct UniProtKB {GO:0005515=PMID:21988832, GO:0035136=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0016567=GO_REF:0000041, GO:0051216=PMID:21547890, GO:0005634=PMID:11929873, GO:0009952=GO_REF:0000019, GO:0045778=PMID:21547890, GO:0042803=PMID:8622986, GO:0042802=PMID:9294197, GO:0009880=GO_REF:0000019, GO:0045638=PMID:8541544, GO:0017053=PMID:12802276, GO:0030099=PMID:9294197, GO:0032332=PMID:21547890, GO:0030097=PMID:8541544, GO:0006355=GO_REF:0000019, GO:0043065=GO_REF:0000019, GO:0001823=PMID:8541544, GO:0006915=PMID:9294197, GO:0048133=GO_REF:0000019, GO:0007417=PMID:8541544, GO:0003677=PMID:12802276, GO:0006351=GO_REF:0000037, GO:0016604=PMID:19648967, GO:0001501=GO_REF:0000019, GO:0016607=PMID:8541544, GO:0016605=PMID:9294197, GO:0045600=PMID:21547890, GO:0061036=PMID:21547890, GO:0035116=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0045893=PMID:21547890, GO:0045892=PMID:12802276} Q05516 Zinc finger and BTB domain-containing protein 16 protein 20130415 {GO:0005515=IPI, GO:0035136=IEA, GO:0008285=IEA, GO:0016567=IEA, GO:0051216=IDA, GO:0005634=IDA, GO:0009952=IEA, GO:0045778=IDA, GO:0042803=IDA, GO:0042802=IPI, GO:0009880=IEA, GO:0045638=ISS, GO:0017053=IDA, GO:0030099=TAS, GO:0032332=IMP, GO:0030097=IDA, GO:0006355=IEA, GO:0043065=IEA, GO:0001823=ISS, GO:0006915=NAS, GO:0048133=IEA, GO:0007417=ISS, GO:0003677=IDA, GO:0006351=IEA, GO:0016604=IDA, GO:0001501=IEA, GO:0016607=IDA, GO:0016605=IDA, GO:0045600=IMP, GO:0061036=IDA, GO:0035116=IEA, GO:0008270=IEA, GO:0045893=IDA, GO:0045892=IDA} anterior/posterior pattern specification, apoptotic process, cartilage development, central nervous system development, embryonic hindlimb morphogenesis, embryonic pattern specification, forelimb morphogenesis, hemopoiesis, male germ-line stem cell division, mesonephros development, myeloid cell differentiation, negative regulation of cell proliferation, negative regulation of myeloid cell differentiation, negative regulation of transcription, DNA-dependent, positive regulation of apoptotic process, positive regulation of cartilage development, positive regulation of chondrocyte differentiation, positive regulation of fat cell differentiation, positive regulation of ossification, positive regulation of transcription, DNA-dependent, protein ubiquitination, regulation of transcription, DNA-dependent, skeletal system development, transcription, DNA-dependent PML body, nuclear body, nuclear speck, nucleus, transcriptional repressor complex DNA binding, identical protein binding, protein binding, protein homodimerization activity, zinc ion binding Human UniProtKB:Q05516 ZBTB17 IntAct UniProtKB {GO:0005515=PMID:16352593, GO:0003700=PMID:12244100, GO:0005634=GO_REF:0000038, GO:0003676=GO_REF:0000002, GO:0007398=GO_REF:0000019, GO:0045786=PMID:12244100, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0001702=GO_REF:0000019, GO:0030968=Reactome:REACT_18356, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_116103, GO:0045893=GO_REF:0000019, GO:0006987=Reactome:REACT_18368, GO:0044267=Reactome:REACT_17015} Q13105 Zinc finger and BTB domain-containing protein 17 protein 20130415 {GO:0005515=IPI, GO:0003700=IDA, GO:0005634=IEA, GO:0003676=IEA, GO:0007398=IEA, GO:0045786=TAS, GO:0003677=IEA, GO:0006351=IEA, GO:0001702=IEA, GO:0030968=TAS, GO:0008270=IEA, GO:0005654=TAS, GO:0045893=IEA, GO:0006987=TAS, GO:0044267=TAS} activation of signaling protein activity involved in unfolded protein response, cellular protein metabolic process, ectoderm development, endoplasmic reticulum unfolded protein response, gastrulation with mouth forming second, negative regulation of cell cycle, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleoplasm, nucleus DNA binding, nucleic acid binding, protein binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB:P01106 ZBTB2 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8N680 Zinc finger and BTB domain-containing protein 2 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZBTB20 HPA UniProtKB {GO:0001078=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000019} Q9HC78 Zinc finger and BTB domain-containing protein 20 protein 20090616 {GO:0001078=IEA, GO:0005730=IDA, GO:0008270=IEA, GO:0005634=IDA, GO:0003677=IEA} nucleolus, nucleus DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, zinc ion binding NOT Human ZBTB22 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O15209 Zinc finger and BTB domain-containing protein 22 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZBTB24 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O43167 Zinc finger and BTB domain-containing protein 24 protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, protein binding, zinc ion binding Human UniProtKB:Q99750 ZBTB25 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0010467=PMID:2027750, GO:0005737=PMID:2027750, GO:0003700=PMID:2027750, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=PMID:2027750, GO:0006351=GO_REF:0000037} P24278 Zinc finger and BTB domain-containing protein 25 protein 20130415 {GO:0005515=IPI, GO:0010467=IEP, GO:0005737=IDA, GO:0003700=TAS, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IDA, GO:0006351=IEA} gene expression, transcription, DNA-dependent cytoplasm, nucleus DNA binding, protein binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB:Q99750 ZBTB26 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9HCK0 Zinc finger and BTB domain-containing protein 26 protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0005575=ND, GO:0003677=IEA, GO:0006351=IEA} biological_process, regulation of transcription, DNA-dependent, transcription, DNA-dependent cellular_component, nucleus DNA binding, molecular_function, zinc ion binding Human ZBTB3 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9H5J0 Zinc finger and BTB domain-containing protein 3 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZBTB32 Reactome UniProtKB {GO:0030097=GO_REF:0000019, GO:0006366=PMID:10572087, GO:0003714=GO_REF:0000019, GO:0005634=PMID:10572087, GO:0000228=GO_REF:0000019, GO:0000122=PMID:10572087, GO:0003676=GO_REF:0000002, GO:0001817=GO_REF:0000019, GO:0003677=GO_REF:0000024, GO:0006281=Reactome:REACT_216, GO:0042098=GO_REF:0000019, GO:0008270=GO_REF:0000024, GO:0005654=Reactome:REACT_18350} Q9Y2Y4 Zinc finger and BTB domain-containing protein 32 protein 20130213 {GO:0030097=IEA, GO:0006366=TAS, GO:0003714=IEA, GO:0005634=TAS, GO:0000228=IEA, GO:0000122=TAS, GO:0003676=IEA, GO:0001817=IEA, GO:0003677=ISS, GO:0006281=TAS, GO:0042098=IEA, GO:0008270=ISS, GO:0005654=TAS} DNA repair, T cell proliferation, hemopoiesis, negative regulation of transcription from RNA polymerase II promoter, regulation of cytokine production, transcription from RNA polymerase II promoter nuclear chromosome, nucleoplasm, nucleus DNA binding, nucleic acid binding, transcription corepressor activity, zinc ion binding Human ZBTB33 HPA UniProtKB {GO:0035556=PMID:10207085, GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0016055=GO_REF:0000037, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q86T24 Transcriptional regulator Kaiso protein 20101115 {GO:0035556=TAS, GO:0005737=IDA, GO:0006355=IEA, GO:0005886=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0016055=IEA, GO:0003677=IEA, GO:0006351=IEA} Wnt receptor signaling pathway, intracellular signal transduction, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleolus, nucleus, plasma membrane DNA binding, zinc ion binding Human ZBTB37 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q5TC79 Zinc finger and BTB domain-containing protein 37 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZBTB38 HPA UniProtKB {GO:0003700=GO_REF:0000024, GO:0045944=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8NAP3 Zinc finger and BTB domain-containing protein 38 protein 20101115 {GO:0003700=ISS, GO:0045944=ISS, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleolus, nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding transcription factor activity, zinc ion binding NOT Human ZBTB39 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O15060 Zinc finger and BTB domain-containing protein 39 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZBTB4 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9P1Z0 Zinc finger and BTB domain-containing protein 4 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZBTB40 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0006355=GO_REF:0000037, GO:0005634=PMID:15302935, GO:0008270=GO_REF:0000002, GO:0030282=PMID:20554715, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006974=PMID:17525332, GO:0006351=GO_REF:0000037} Q9NUA8 Zinc finger and BTB domain-containing protein 40 protein 20110520 {GO:0003674=ND, GO:0006355=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0030282=NAS, GO:0003676=IEA, GO:0003677=IEA, GO:0006974=IDA, GO:0006351=IEA} bone mineralization, regulation of transcription, DNA-dependent, response to DNA damage stimulus, transcription, DNA-dependent nucleus DNA binding, molecular_function, nucleic acid binding, zinc ion binding Human ZBTB41 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q5SVQ8 Zinc finger and BTB domain-containing protein 41 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZBTB43 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O43298 Zinc finger and BTB domain-containing protein 43 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZBTB44 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8NCP5 Zinc finger and BTB domain-containing protein 44 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZBTB45 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96K62 Zinc finger and BTB domain-containing protein 45 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZBTB46 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q86UZ6 Zinc finger and BTB domain-containing protein 46 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZBTB47 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9UFB7 Zinc finger and BTB domain-containing protein 47 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZBTB48 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0003700=PMID:8661141, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q5SY21 Zinc finger and BTB domain-containing protein 48 protein 20101115 {GO:0005737=IDA, GO:0003700=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} transcription, DNA-dependent cytoplasm, nucleolus, nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZBTB49 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6ZSB9 Zinc finger and BTB domain-containing protein 49 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZBTB5 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O15062 Zinc finger and BTB domain-containing protein 5 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZBTB6 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q15916 Zinc finger and BTB domain-containing protein 6 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZBTB7A UniProtKB UniProtKB {GO:0035035=PMID:15337766, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0000122=GO_REF:0000019, GO:0003677=PMID:15337766, GO:0045892=PMID:15337766, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037} O95365 Zinc finger and BTB domain-containing protein 7A protein 20050609 {GO:0035035=ISS, GO:0005634=IEA, GO:0007275=IEA, GO:0008270=IEA, GO:0000122=IEA, GO:0003677=ISS, GO:0045892=ISS, GO:0030154=IEA, GO:0006351=IEA} cell differentiation, multicellular organismal development, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, histone acetyltransferase binding, zinc ion binding Human UniProtKB:O88939 ZBTB7B HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0006366=PMID:7937772, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0007275=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0007398=PMID:7937772, GO:0003677=GO_REF:0000037, GO:0030154=GO_REF:0000037} O15156 Zinc finger and BTB domain-containing protein 7B protein 20090616 {GO:0006355=IEA, GO:0006366=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0007275=IEA, GO:0008270=IEA, GO:0007398=TAS, GO:0003677=IEA, GO:0030154=IEA} cell differentiation, ectoderm development, multicellular organismal development, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter nucleolus, nucleus DNA binding, zinc ion binding NOT Human ZBTB7C InterPro UniProtKB {GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} A1YPR0 Zinc finger and BTB domain-containing protein 7C protein 20130413 {GO:0008270=IEA, GO:0003676=IEA} nucleic acid binding, zinc ion binding Human InterPro:IPR007087 ZBTB8A UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96BR9 Zinc finger and BTB domain-containing protein 8A protein 20090713 {GO:0003674=ND, GO:0008150=ND, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0005575=ND, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} biological_process, regulation of transcription, DNA-dependent, transcription, DNA-dependent cellular_component, nucleus DNA binding, molecular_function, nucleic acid binding, zinc ion binding Human ZBTB8B UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8NAP8 Zinc finger and BTB domain-containing protein 8B protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZBTB8OS null null {} null null null null {} null null null ZBTB9 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96C00 Zinc finger and BTB domain-containing protein 9 protein 20110516 {GO:0005739=IDA, GO:0006355=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent mitochondrion, nucleolus, nucleus DNA binding, zinc ion binding Human ZC3H10 IntAct UniProtKB {GO:0005515=PMID:23275563, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q96K80 Zinc finger CCCH domain-containing protein 10 protein 20130415 {GO:0005515=IPI, GO:0008270=IEA, GO:0003676=IEA} nucleic acid binding, protein binding, zinc ion binding Human UniProtKB:P54253 ZC3H11A IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} O75152 Zinc finger CCCH domain-containing protein 11A protein 20130415 {GO:0005515=IPI, GO:0008270=IEA, GO:0003676=IEA} nucleic acid binding, protein binding, zinc ion binding Human UniProtKB:P40692 ZC3H12A BHF-UCL UniProtKB {GO:0005515=PMID:21988832, GO:0005886=GO_REF:0000052, GO:0032715=PMID:18178554, GO:0043031=PMID:18178554, GO:0005730=GO_REF:0000052, GO:0006915=GO_REF:0000037, GO:0032720=PMID:18178554, GO:0010884=PMID:22739135, GO:0032088=PMID:18178554, GO:0005634=GO_REF:0000052, GO:0001525=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0005737=PMID:18178554, GO:0004519=GO_REF:0000037, GO:0071222=PMID:18178554, GO:0045019=PMID:18178554, GO:0010629=PMID:18178554, GO:0045600=PMID:22739135, GO:0010508=PMID:22739135} Q5D1E8 Ribonuclease ZC3H12A protein 20130118 {GO:0005515=IPI, GO:0005886=IDA, GO:0032715=IDA, GO:0043031=IC, GO:0005730=IDA, GO:0006915=IEA, GO:0032720=IDA, GO:0010884=IDA, GO:0032088=IDA, GO:0005634=IDA, GO:0001525=IEA, GO:0030154=IEA, GO:0046872=IEA, GO:0005737=IDA, GO:0004519=IEA, GO:0071222=IDA, GO:0045019=IDA, GO:0010629=IDA, GO:0045600=IDA, GO:0010508=IDA} angiogenesis, apoptotic process, cell differentiation, cellular response to lipopolysaccharide, negative regulation of NF-kappaB transcription factor activity, negative regulation of gene expression, negative regulation of interleukin-6 production, negative regulation of macrophage activation, negative regulation of nitric oxide biosynthetic process, negative regulation of tumor necrosis factor production, positive regulation of autophagy, positive regulation of fat cell differentiation, positive regulation of lipid storage cytoplasm, nucleolus, nucleus, plasma membrane endonuclease activity, metal ion binding, protein binding Human ZC3H12C BHF-UCL UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0004519=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0003676=GO_REF:0000002} Q9C0D7 Probable ribonuclease ZC3H12C protein 20130118 {GO:0003674=ND, GO:0008150=ND, GO:0004519=IEA, GO:0008270=IEA, GO:0005575=ND, GO:0003676=IEA} biological_process cellular_component endonuclease activity, molecular_function, nucleic acid binding, zinc ion binding Human ZC3H13 InterPro UniProtKB {GO:0005515=PMID:20195357, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q5T9K0 Zinc finger CCCH domain-containing protein 13 protein 20130413 {GO:0005515=IPI, GO:0008270=IEA, GO:0003676=IEA} nucleic acid binding, protein binding, zinc ion binding Human InterPro:IPR000571 ZC3H14 HPA UniProtKB {GO:0005515=PMID:19273536, GO:0005737=GO_REF:0000052, GO:0016607=GO_REF:0000039, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q6PJT7 Zinc finger CCCH domain-containing protein 14 protein 20120912 {GO:0005515=IPI, GO:0005737=IDA, GO:0016607=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003676=IEA} cytoplasm, nuclear speck, nucleolus, nucleus RNA binding, nucleic acid binding, protein binding, zinc ion binding Human ZC3H15 HPA UniProtKB {GO:0005515=PMID:19819225, GO:0005737=GO_REF:0000052, GO:0019221=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002} Q8WU90 Zinc finger CCCH domain-containing protein 15 protein 20110516 {GO:0005515=IPI, GO:0005737=IDA, GO:0019221=IEA, GO:0005730=IDA, GO:0008270=IEA, GO:0005634=IDA, GO:0003676=IEA} cytokine-mediated signaling pathway cytoplasm, nucleolus, nucleus nucleic acid binding, protein binding, zinc ion binding Human ZC3H18 HPA UniProtKB {GO:0005730=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002} Q86VM9 Zinc finger CCCH domain-containing protein 18 protein 20111111 {GO:0005730=IDA, GO:0008270=IEA, GO:0005634=IDA, GO:0003676=IEA} nucleolus, nucleus nucleic acid binding, zinc ion binding NOT Human ZC3H3 MGI UniProtKB {GO:0003674=GO_REF:0000015, GO:0006378=PMID:19364924, GO:0016973=PMID:19364924, GO:0005634=PMID:16115198, GO:0008270=GO_REF:0000002, GO:0010793=PMID:19364924, GO:0003676=GO_REF:0000002} Q8IXZ2 Zinc finger CCCH domain-containing protein 3 protein 20121024 {GO:0003674=ND, GO:0006378=IMP, GO:0016973=IMP, GO:0005634=IDA, GO:0008270=IEA, GO:0010793=IMP, GO:0003676=IEA} mRNA polyadenylation, poly(A)+ mRNA export from nucleus, regulation of mRNA export from nucleus nucleus molecular_function, nucleic acid binding, zinc ion binding Human ZC3H4 InterPro UniProtKB {GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q9UPT8 Zinc finger CCCH domain-containing protein 4 protein 20130413 {GO:0008270=IEA, GO:0003676=IEA} nucleic acid binding, zinc ion binding Human InterPro:IPR000571 ZC3H7A UniProtKB UniProtKB {GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q8IWR0 Zinc finger CCCH domain-containing protein 7A protein 20130413 {GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA} nucleus nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZC3H7B IntAct UniProtKB {GO:0005515=PMID:15047801, GO:0019048=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q9UGR2 Zinc finger CCCH domain-containing protein 7B protein 20130415 {GO:0005515=IPI, GO:0019048=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA} virus-host interaction nucleus nucleic acid binding, protein binding, zinc ion binding Human UniProtKB:Q00721 ZC3H8 UniProtKB UniProtKB {GO:0043565=GO_REF:0000024, GO:0003700=PMID:12153508, GO:0033085=PMID:12153508, GO:0003723=GO_REF:0000037, GO:0070245=PMID:12153508, GO:0006915=GO_REF:0000037, GO:0005634=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0043029=PMID:12153508, GO:0045892=GO_REF:0000024, GO:0046677=PMID:12153508, GO:0006351=GO_REF:0000037} Q8N5P1 Zinc finger CCCH domain-containing protein 8 protein 20090703 {GO:0043565=ISS, GO:0003700=IMP, GO:0033085=IMP, GO:0003723=IEA, GO:0070245=IMP, GO:0006915=IEA, GO:0005634=ISS, GO:0008270=IEA, GO:0043029=IMP, GO:0045892=ISS, GO:0046677=IDA, GO:0006351=IEA} T cell homeostasis, apoptotic process, negative regulation of T cell differentiation in thymus, negative regulation of transcription, DNA-dependent, positive regulation of thymocyte apoptotic process, response to antibiotic, transcription, DNA-dependent nucleus RNA binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZC3HAV1 HPA UniProtKB {GO:0005515=PMID:21102435, GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000052, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002, GO:0009615=PMID:21876179, GO:0003950=GO_REF:0000002, GO:0071360=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0051607=GO_REF:0000037, GO:0045087=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0032481=GO_REF:0000019, GO:0061014=PMID:21876179, GO:0045071=PMID:21876179} Q7Z2W4 Zinc finger CCCH-type antiviral protein 1 protein 20120912 {GO:0005515=IPI, GO:0005794=IDA, GO:0005886=IDA, GO:0003723=IEA, GO:0005634=IEA, GO:0003676=IEA, GO:0009615=IDA, GO:0003950=IEA, GO:0071360=IEA, GO:0005737=IDA, GO:0051607=IEA, GO:0045087=IEA, GO:0008270=IEA, GO:0032481=IEA, GO:0061014=IDA, GO:0045071=IDA} cellular response to exogenous dsRNA, defense response to virus, innate immune response, negative regulation of viral genome replication, positive regulation of mRNA catabolic process, positive regulation of type I interferon production, response to virus Golgi apparatus, cytoplasm, nucleus, plasma membrane NAD+ ADP-ribosyltransferase activity, RNA binding, nucleic acid binding, protein binding, zinc ion binding Human ZC3HAV1L null null {} null null null null {} null null null ZC3HC1 HPA UniProtKB {GO:0005515=PMID:16105984, GO:0031965=GO_REF:0000052, GO:0007067=GO_REF:0000037, GO:0043066=GO_REF:0000019, GO:0016567=GO_REF:0000041, GO:0019901=PMID:16105984, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000054, GO:0051301=GO_REF:0000037} Q86WB0 Nuclear-interacting partner of ALK protein 20111111 {GO:0005515=IPI, GO:0031965=IDA, GO:0007067=IEA, GO:0043066=IEA, GO:0016567=IEA, GO:0019901=IPI, GO:0008270=IEA, GO:0005634=IDA, GO:0051301=IEA} cell division, mitosis, negative regulation of apoptotic process, protein ubiquitination nuclear membrane, nucleus protein binding, protein kinase binding, zinc ion binding Human ZC4H2 UniProtKB UniProtKB {GO:0046872=GO_REF:0000037} Q9NQZ6 Zinc finger C4H2 domain-containing protein protein 20130413 {GO:0046872=IEA} metal ion binding Human UniProtKB-KW:KW-0479 ZCCHC10 InterPro UniProtKB {GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q8TBK6 Zinc finger CCHC domain-containing protein 10 protein 20130413 {GO:0008270=IEA, GO:0003676=IEA} nucleic acid binding, zinc ion binding Human InterPro:IPR001878 ZCCHC11 HPA UniProtKB {GO:0005515=PMID:19703396, GO:0032755=GO_REF:0000019, GO:0016779=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0031123=PMID:19703396, GO:0005634=GO_REF:0000019, GO:0032088=GO_REF:0000019, GO:0001816=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0010587=PMID:19703396, GO:0050265=PMID:19703396, GO:0010586=GO_REF:0000024, GO:0005737=GO_REF:0000052, GO:0019827=PMID:19703396, GO:0031054=PMID:19703396, GO:0071044=PMID:18172165, GO:0031664=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0070102=GO_REF:0000019} Q5TAX3 Terminal uridylyltransferase 4 protein 20110516 {GO:0005515=IPI, GO:0032755=IEA, GO:0016779=IEA, GO:0005730=IDA, GO:0031123=IDA, GO:0005634=IEA, GO:0032088=IEA, GO:0001816=IEA, GO:0003676=IEA, GO:0010587=IMP, GO:0050265=IDA, GO:0010586=ISS, GO:0005737=IDA, GO:0019827=IMP, GO:0031054=IMP, GO:0071044=IMP, GO:0031664=IEA, GO:0008270=IEA, GO:0070102=IEA} RNA 3'-end processing, cytokine production, histone mRNA catabolic process, interleukin-6-mediated signaling pathway, miRNA catabolic process, miRNA metabolic process, negative regulation of NF-kappaB transcription factor activity, positive regulation of interleukin-6 production, pre-miRNA processing, regulation of lipopolysaccharide-mediated signaling pathway, stem cell maintenance cytoplasm, nucleolus, nucleus RNA uridylyltransferase activity, nucleic acid binding, nucleotidyltransferase activity, protein binding, zinc ion binding Human ZCCHC12 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q6PEW1 Zinc finger CCHC domain-containing protein 12 protein 20130413 {GO:0006355=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleic acid binding, zinc ion binding Human UniProtKB-KW:KW-0805 ZCCHC13 InterPro UniProtKB {GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q8WW36 Zinc finger CCHC domain-containing protein 13 protein 20130413 {GO:0008270=IEA, GO:0003676=IEA} nucleic acid binding, zinc ion binding Human InterPro:IPR001878 ZCCHC14 InterPro UniProtKB {GO:0007154=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0035091=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q8WYQ9 Zinc finger CCHC domain-containing protein 14 protein 20130413 {GO:0007154=IEA, GO:0008270=IEA, GO:0035091=IEA, GO:0003676=IEA} cell communication nucleic acid binding, phosphatidylinositol binding, zinc ion binding Human InterPro:IPR001683 ZCCHC17 UniProtKB UniProtKB {GO:0003723=GO_REF:0000002, GO:0005730=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0022625=GO_REF:0000019} Q9NP64 Nucleolar protein of 40 kDa protein 20130413 {GO:0003723=IEA, GO:0005730=IEA, GO:0008270=IEA, GO:0022625=IEA} cytosolic large ribosomal subunit, nucleolus RNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0188 ZCCHC2 LIFEdb UniProtKB {GO:0005737=GO_REF:0000054, GO:0007154=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0035091=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q9C0B9 Zinc finger CCHC domain-containing protein 2 protein 20100607 {GO:0005737=IDA, GO:0007154=IEA, GO:0008270=IEA, GO:0035091=IEA, GO:0003676=IEA} cell communication cytoplasm nucleic acid binding, phosphatidylinositol binding, zinc ion binding Human ZCCHC24 InterPro UniProtKB {GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q8N2G6 Zinc finger CCHC domain-containing protein 24 protein 20130413 {GO:0008270=IEA, GO:0003676=IEA} nucleic acid binding, zinc ion binding Human InterPro:IPR001878 ZCCHC3 InterPro UniProtKB {GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q9NUD5 Zinc finger CCHC domain-containing protein 3 protein 20130413 {GO:0008270=IEA, GO:0003676=IEA} nucleic acid binding, zinc ion binding Human InterPro:IPR001878 ZCCHC6 UniProtKB UniProtKB {GO:0071044=PMID:18172165, GO:0031123=PMID:17353264, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0050265=PMID:17353264} Q5VYS8 Terminal uridylyltransferase 7 protein 20091202 {GO:0071044=IMP, GO:0031123=IDA, GO:0008270=IEA, GO:0003676=IEA, GO:0050265=IDA} RNA 3'-end processing, histone mRNA catabolic process RNA uridylyltransferase activity, nucleic acid binding, zinc ion binding NOT Human ZCCHC7 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q8N3Z6 Zinc finger CCHC domain-containing protein 7 protein 20100326 {GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003676=IEA} cytoplasm, nucleolus, nucleus nucleic acid binding, zinc ion binding Human ZCCHC8 HPA UniProtKB {GO:0005515=PMID:17525332, GO:0000398=PMID:11991638, GO:0005730=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0071013=PMID:11991638, GO:0003676=GO_REF:0000002} Q6NZY4 Zinc finger CCHC domain-containing protein 8 protein 20111111 {GO:0005515=IPI, GO:0000398=IC, GO:0005730=IDA, GO:0008270=IEA, GO:0005634=IDA, GO:0071013=IDA, GO:0003676=IEA} mRNA splicing, via spliceosome catalytic step 2 spliceosome, nucleolus, nucleus nucleic acid binding, protein binding, zinc ion binding NOT Human ZCCHC9 UniProtKB UniProtKB {GO:0010923=PMID:19389623, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q8N567 Zinc finger CCHC domain-containing protein 9 protein 20111103 {GO:0010923=IDA, GO:0008270=IEA, GO:0003676=IEA} negative regulation of phosphatase activity nucleic acid binding, zinc ion binding Human ZCRB1 HGNC UniProtKB {GO:0008380=PMID:15146077, GO:0006397=GO_REF:0000037, GO:0000166=GO_REF:0000002, GO:0003723=GO_REF:0000037, GO:0005654=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0005689=PMID:15146077} Q8TBF4 Zinc finger CCHC-type and RNA-binding motif-containing protein 1 protein 20060131 {GO:0008380=IC, GO:0006397=IEA, GO:0000166=IEA, GO:0003723=IEA, GO:0005654=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0005689=IDA} RNA splicing, mRNA processing U12-type spliceosomal complex, nucleoplasm RNA binding, nucleic acid binding, nucleotide binding, zinc ion binding Human GO:0005689 ZCWPW2 InterPro UniProtKB {GO:0008270=GO_REF:0000002} Q504Y3 Zinc finger CW-type PWWP domain protein 2 protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR011124 ZDBF2 InterPro UniProtKB {GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q9HCK1 DBF4-type zinc finger-containing protein 2 protein 20130413 {GO:0008270=IEA, GO:0003676=IEA} nucleic acid binding, zinc ion binding Human InterPro:IPR006572 ZDHHC1 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0018345=GO_REF:0000019, GO:0016409=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0016021=GO_REF:0000037, GO:0003677=PMID:10395086} Q8WTX9 Probable palmitoyltransferase ZDHHC1 protein 20061026 {GO:0008150=ND, GO:0018345=IEA, GO:0016409=IEA, GO:0008270=IEA, GO:0005575=ND, GO:0016021=IEA, GO:0003677=NAS} biological_process, protein palmitoylation cellular_component, integral to membrane DNA binding, palmitoyltransferase activity, zinc ion binding Human ZDHHC12 UniProtKB UniProtKB {GO:0016746=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q96GR4 Probable palmitoyltransferase ZDHHC12 protein 20130413 {GO:0016746=IEA, GO:0008270=IEA, GO:0016021=IEA} integral to membrane transferase activity, transferring acyl groups, zinc ion binding Human UniProtKB-KW:KW-0012 ZDHHC13 GOC UniProtKB {GO:0007165=PMID:12761501, GO:0005794=GO_REF:0000052, GO:0000139=GO_REF:0000024, GO:0030660=GO_REF:0000024, GO:0015095=GO_REF:0000024, GO:0016409=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0004871=PMID:12761501, GO:0016021=GO_REF:0000037, GO:0043123=PMID:12761501, GO:0043231=GO_REF:0000052} Q8IUH4 Palmitoyltransferase ZDHHC13 protein 20130413 {GO:0007165=IMP, GO:0005794=IDA, GO:0000139=ISS, GO:0030660=ISS, GO:0015095=ISS, GO:0016409=ISS, GO:0008270=IEA, GO:0004871=IMP, GO:0016021=IEA, GO:0043123=IMP, GO:0043231=IDA} positive regulation of I-kappaB kinase/NF-kappaB cascade, signal transduction Golgi apparatus, Golgi membrane, Golgi-associated vesicle membrane, integral to membrane, intracellular membrane-bounded organelle magnesium ion transmembrane transporter activity, palmitoyltransferase activity, signal transducer activity, zinc ion binding Human ZDHHC14 UniProtKB UniProtKB {GO:0016746=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q8IZN3 Probable palmitoyltransferase ZDHHC14 protein 20130413 {GO:0016746=IEA, GO:0008270=IEA, GO:0016021=IEA} integral to membrane transferase activity, transferring acyl groups, zinc ion binding Human UniProtKB-KW:KW-0012 ZDHHC15 ENSEMBL UniProtKB {GO:0018345=GO_REF:0000019, GO:0016188=GO_REF:0000019, GO:0016409=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0016740=GO_REF:0000038, GO:0045184=GO_REF:0000019} Q96MV8 Palmitoyltransferase ZDHHC15 protein 20130413 {GO:0018345=IEA, GO:0016188=IEA, GO:0016409=IEA, GO:0008270=IEA, GO:0016021=IEA, GO:0016740=IEA, GO:0045184=IEA} establishment of protein localization, protein palmitoylation, synaptic vesicle maturation integral to membrane palmitoyltransferase activity, transferase activity, zinc ion binding Human Ensembl:ENSMUSP00000047615 ZDHHC16 UniProtKB UniProtKB {GO:0016746=GO_REF:0000037, GO:0005789=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q969W1 Probable palmitoyltransferase ZDHHC16 protein 20130413 {GO:0016746=IEA, GO:0005789=IEA, GO:0006915=IEA, GO:0008270=IEA, GO:0016021=IEA} apoptotic process endoplasmic reticulum membrane, integral to membrane transferase activity, transferring acyl groups, zinc ion binding Human UniProtKB-SubCell:SL-0097 ZDHHC17 GOC UniProtKB {GO:0005515=PMID:23275563, GO:0015693=PMID:18794299, GO:0018345=GO_REF:0000019, GO:0005794=GO_REF:0000052, GO:0015095=PMID:18794299, GO:0043231=GO_REF:0000052, GO:0007165=PMID:12761501, GO:0005737=GO_REF:0000052, GO:0042953=PMID:15603740, GO:0000139=PMID:18794299, GO:0030660=PMID:18794299, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0004871=PMID:12761501, GO:0043123=PMID:12761501, GO:0019706=PMID:15603740} Q8IUH5 Palmitoyltransferase ZDHHC17 protein 20130413 {GO:0005515=IPI, GO:0015693=IDA, GO:0018345=IEA, GO:0005794=IDA, GO:0015095=IDA, GO:0043231=IDA, GO:0007165=IMP, GO:0005737=IDA, GO:0042953=IDA, GO:0000139=IDA, GO:0030660=IDA, GO:0008270=IEA, GO:0016021=IEA, GO:0004871=IMP, GO:0043123=IMP, GO:0019706=IDA} lipoprotein transport, magnesium ion transport, positive regulation of I-kappaB kinase/NF-kappaB cascade, protein palmitoylation, signal transduction Golgi apparatus, Golgi membrane, Golgi-associated vesicle membrane, cytoplasm, integral to membrane, intracellular membrane-bounded organelle magnesium ion transmembrane transporter activity, protein binding, protein-cysteine S-palmitoleyltransferase activity, signal transducer activity, zinc ion binding Human ZDHHC2 ENSEMBL UniProtKB {GO:0018345=GO_REF:0000019, GO:0016409=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q9UIJ5 Palmitoyltransferase ZDHHC2 protein 20130413 {GO:0018345=IEA, GO:0016409=IEA, GO:0008270=IEA, GO:0016021=IEA} protein palmitoylation integral to membrane palmitoyltransferase activity, zinc ion binding Human Ensembl:ENSMUSP00000041727 ZDHHC20 UniProtKB UniProtKB {GO:0016746=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0016740=GO_REF:0000038} Q5W0Z9 Probable palmitoyltransferase ZDHHC20 protein 20130413 {GO:0016746=IEA, GO:0008270=IEA, GO:0016021=IEA, GO:0016740=IEA} integral to membrane transferase activity, transferase activity, transferring acyl groups, zinc ion binding Human UniProtKB-KW:KW-0012 ZDHHC21 Reactome UniProtKB {GO:0005794=PMID:22031296, GO:0000139=Reactome:REACT_12530, GO:0018230=PMID:22031296, GO:0050999=Reactome:REACT_12477, GO:0048733=GO_REF:0000019, GO:0016409=GO_REF:0000019, GO:0046209=Reactome:REACT_12508, GO:0008270=GO_REF:0000002, GO:0044281=Reactome:REACT_111217, GO:0016021=GO_REF:0000037, GO:0001942=GO_REF:0000019} Q8IVQ6 Palmitoyltransferase ZDHHC21 protein 20130301 {GO:0005794=IDA, GO:0000139=TAS, GO:0018230=IMP, GO:0050999=TAS, GO:0048733=IEA, GO:0016409=IEA, GO:0046209=TAS, GO:0008270=IEA, GO:0044281=TAS, GO:0016021=IEA, GO:0001942=IEA} hair follicle development, nitric oxide metabolic process, peptidyl-L-cysteine S-palmitoylation, regulation of nitric-oxide synthase activity, sebaceous gland development, small molecule metabolic process Golgi apparatus, Golgi membrane, integral to membrane palmitoyltransferase activity, zinc ion binding Human ZDHHC23 UniProtKB UniProtKB {GO:0016746=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0016740=GO_REF:0000038} Q8IYP9 Probable palmitoyltransferase ZDHHC23 protein 20130413 {GO:0016746=IEA, GO:0008270=IEA, GO:0016021=IEA, GO:0016740=IEA} integral to membrane transferase activity, transferase activity, transferring acyl groups, zinc ion binding Human UniProtKB-KW:KW-0012 ZDHHC3 UniProtKB UniProtKB {GO:0018345=GO_REF:0000019, GO:0005794=GO_REF:0000019, GO:0000139=GO_REF:0000039, GO:0016409=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0006605=GO_REF:0000019} Q9NYG2 Palmitoyltransferase ZDHHC3 protein 20130413 {GO:0018345=IEA, GO:0005794=IEA, GO:0000139=IEA, GO:0016409=IEA, GO:0008270=IEA, GO:0016021=IEA, GO:0006605=IEA} protein palmitoylation, protein targeting Golgi apparatus, Golgi membrane, integral to membrane palmitoyltransferase activity, zinc ion binding Human UniProtKB-SubCell:SL-0134 ZDHHC4 UniProtKB UniProtKB {GO:0016746=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q9NPG8 Probable palmitoyltransferase ZDHHC4 protein 20130413 {GO:0016746=IEA, GO:0008270=IEA, GO:0016021=IEA} integral to membrane transferase activity, transferring acyl groups, zinc ion binding Human UniProtKB-KW:KW-0012 ZDHHC5 MGI UniProtKB {GO:0018345=PMID:22325201, GO:0005886=GO_REF:0000039, GO:0016409=PMID:22325201, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q9C0B5 Palmitoyltransferase ZDHHC5 protein 20121130 {GO:0018345=IDA, GO:0005886=IEA, GO:0016409=IDA, GO:0008270=IEA, GO:0016021=IEA} protein palmitoylation integral to membrane, plasma membrane palmitoyltransferase activity, zinc ion binding Human ZDHHC6 UniProtKB UniProtKB {GO:0016746=GO_REF:0000037, GO:0005789=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q9H6R6 Palmitoyltransferase ZDHHC6 protein 20130413 {GO:0016746=IEA, GO:0005789=IEA, GO:0008270=IEA, GO:0016021=IEA} endoplasmic reticulum membrane, integral to membrane transferase activity, transferring acyl groups, zinc ion binding Human UniProtKB-SubCell:SL-0097 ZDHHC7 UniProtKB UniProtKB {GO:0018345=GO_REF:0000019, GO:0005794=PMID:22031296, GO:0018230=PMID:22031296, GO:0016409=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q9NXF8 Palmitoyltransferase ZDHHC7 protein 20120507 {GO:0018345=IEA, GO:0005794=IDA, GO:0018230=IMP, GO:0016409=IEA, GO:0008270=IEA, GO:0016021=IEA} peptidyl-L-cysteine S-palmitoylation, protein palmitoylation Golgi apparatus, integral to membrane palmitoyltransferase activity, zinc ion binding Human ZDHHC8 UniProtKB UniProtKB {GO:0005739=GO_REF:0000019, GO:0016746=GO_REF:0000037, GO:0007610=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037, GO:0030659=GO_REF:0000039} Q9ULC8 Probable palmitoyltransferase ZDHHC8 protein 20130413 {GO:0005739=IEA, GO:0016746=IEA, GO:0007610=IEA, GO:0008270=IEA, GO:0016021=IEA, GO:0030659=IEA} behavior cytoplasmic vesicle membrane, integral to membrane, mitochondrion transferase activity, transferring acyl groups, zinc ion binding Human UniProtKB-SubCell:SL-0089 ZDHHC9 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0016746=GO_REF:0000037, GO:0000139=GO_REF:0000039, GO:0005789=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q9Y397 Palmitoyltransferase ZDHHC9 protein 20101115 {GO:0005737=IDA, GO:0005794=IDA, GO:0016746=IEA, GO:0000139=IEA, GO:0005789=IEA, GO:0008270=IEA, GO:0016021=IEA} Golgi apparatus, Golgi membrane, cytoplasm, endoplasmic reticulum membrane, integral to membrane transferase activity, transferring acyl groups, zinc ion binding Human ZEB1 HPA UniProtKB {GO:0005515=PMID:20418909, GO:0007389=GO_REF:0000019, GO:0008285=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0010464=GO_REF:0000019, GO:0008283=PMID:1840704, GO:0051216=GO_REF:0000019, GO:0071560=GO_REF:0000019, GO:0033081=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0048704=GO_REF:0000019, GO:0048596=GO_REF:0000019, GO:0006955=PMID:1840704, GO:0005737=GO_REF:0000052, GO:0003690=GO_REF:0000019, GO:0071230=GO_REF:0000019, GO:0030857=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0031667=GO_REF:0000019, GO:0017015=GO_REF:0000019, GO:0005667=GO_REF:0000019, GO:0014823=GO_REF:0000019, GO:0006357=PMID:8138542, GO:0051150=GO_REF:0000019, GO:0003714=PMID:8138542, GO:0003713=PMID:8138542, GO:0005730=GO_REF:0000052, GO:0070888=GO_REF:0000024, GO:0000122=PMID:1840704, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0043565=GO_REF:0000002, GO:0045666=GO_REF:0000024, GO:0003682=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0030900=GO_REF:0000019, GO:0045892=PMID:12937339, GO:0008134=GO_REF:0000019} Q5VZ84 Zinc finger E-box-binding homeobox 1 protein 20101115 {GO:0005515=IPI, GO:0007389=IEA, GO:0008285=IEA, GO:0003700=IEA, GO:0010464=IEA, GO:0008283=TAS, GO:0051216=IEA, GO:0071560=IEA, GO:0033081=IEA, GO:0005634=IDA, GO:0048704=IEA, GO:0048596=IEA, GO:0006955=TAS, GO:0005737=IDA, GO:0003690=IEA, GO:0071230=IEA, GO:0030857=IEA, GO:0045944=IEA, GO:0031667=IEA, GO:0017015=IEA, GO:0005667=IEA, GO:0014823=IEA, GO:0006357=TAS, GO:0051150=IEA, GO:0003714=TAS, GO:0003713=TAS, GO:0005730=IDA, GO:0070888=ISS, GO:0000122=TAS, GO:0003676=IEA, GO:0006351=IEA, GO:0043565=IEA, GO:0045666=ISS, GO:0003682=IEA, GO:0008270=IEA, GO:0030900=IEA, GO:0045892=IMP, GO:0008134=IEA} cartilage development, cell proliferation, cellular response to amino acid stimulus, cellular response to transforming growth factor beta stimulus, embryonic camera-type eye morphogenesis, embryonic skeletal system morphogenesis, forebrain development, immune response, negative regulation of cell proliferation, negative regulation of epithelial cell differentiation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, pattern specification process, positive regulation of neuron differentiation, positive regulation of transcription from RNA polymerase II promoter, regulation of T cell differentiation in thymus, regulation of mesenchymal cell proliferation, regulation of smooth muscle cell differentiation, regulation of transcription from RNA polymerase II promoter, regulation of transforming growth factor beta receptor signaling pathway, response to activity, response to nutrient levels, transcription, DNA-dependent cytoplasm, nucleolus, nucleus, transcription factor complex E-box binding, chromatin binding, double-stranded DNA binding, nucleic acid binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription coactivator activity, transcription corepressor activity, transcription factor binding, zinc ion binding Human ZEB2 HPA UniProtKB {GO:0021846=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0001756=GO_REF:0000019, GO:0001755=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0001843=GO_REF:0000019, GO:0030177=GO_REF:0000019, GO:0046332=GO_REF:0000029, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0007399=PMID:11279515, GO:0043565=GO_REF:0000002, GO:0021766=GO_REF:0000019, GO:0005737=GO_REF:0000052, GO:0019208=PMID:11477103, GO:0008270=GO_REF:0000002, GO:0043507=GO_REF:0000019} O60315 Zinc finger E-box-binding homeobox 2 protein 20101115 {GO:0021846=IEA, GO:0003700=IEA, GO:0001756=IEA, GO:0001755=IEA, GO:0005730=IDA, GO:0001843=IEA, GO:0030177=IEA, GO:0046332=NAS, GO:0005634=IDA, GO:0003676=IEA, GO:0006351=IEA, GO:0007399=NAS, GO:0043565=IEA, GO:0021766=IEA, GO:0005737=IDA, GO:0019208=NAS, GO:0008270=IEA, GO:0043507=IEA} cell proliferation in forebrain, hippocampus development, nervous system development, neural crest cell migration, neural tube closure, positive regulation of JUN kinase activity, positive regulation of Wnt receptor signaling pathway, somitogenesis, transcription, DNA-dependent cytoplasm, nucleolus, nucleus SMAD binding, nucleic acid binding, phosphatase regulator activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZER1 GOC UniProtKB {GO:0000221=GO_REF:0000002, GO:0004842=PMID:17304241, GO:0016567=PMID:17304241, GO:0046961=GO_REF:0000002, GO:0015991=GO_REF:0000002, GO:0031462=PMID:17304241, GO:0051438=PMID:17304241} Q7Z7L7 Protein zer-1 homolog protein 20130413 {GO:0000221=IEA, GO:0004842=IMP, GO:0016567=IMP, GO:0046961=IEA, GO:0015991=IEA, GO:0031462=IDA, GO:0051438=IMP} ATP hydrolysis coupled proton transport, protein ubiquitination, regulation of ubiquitin-protein ligase activity Cul2-RING ubiquitin ligase complex, vacuolar proton-transporting V-type ATPase, V1 domain proton-transporting ATPase activity, rotational mechanism, ubiquitin-protein ligase activity Human ZFAND1 InterPro UniProtKB {GO:0008270=GO_REF:0000002} Q8TCF1 AN1-type zinc finger protein 1 protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR000058 ZFAND2A UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002} Q8N6M9 AN1-type zinc finger protein 2A protein 20130413 {GO:0005737=IEA, GO:0005634=IEA, GO:0008270=IEA} cytoplasm, nucleus zinc ion binding Human UniProtKB-SubCell:SL-0086 ZFAND2B IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0005783=GO_REF:0000039, GO:0008270=GO_REF:0000002} Q8WV99 AN1-type zinc finger protein 2B protein 20130415 {GO:0005515=IPI, GO:0005783=IEA, GO:0008270=IEA} endoplasmic reticulum protein binding, zinc ion binding Human UniProtKB:Q15038 ZFAND3 InterPro UniProtKB {GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000002} Q9H8U3 AN1-type zinc finger protein 3 protein 20130413 {GO:0008270=IEA, GO:0003677=IEA} DNA binding, zinc ion binding Human InterPro:IPR000058|InterPro:IPR002653 ZFAND4 InterPro UniProtKB {GO:0008270=GO_REF:0000002} Q86XD8 AN1-type zinc finger protein 4 protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR000058 ZFAND5 InterPro UniProtKB {GO:0048705=GO_REF:0000019, GO:0005575=GO_REF:0000015, GO:0003677=GO_REF:0000002, GO:0001701=GO_REF:0000019, GO:0010761=GO_REF:0000019, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0003016=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0048745=GO_REF:0000019, GO:0060324=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0048008=GO_REF:0000019, GO:0001944=GO_REF:0000019} Q5QPB1 AN1-type zinc finger protein 5 protein 20130413 {GO:0048705=IEA, GO:0005575=ND, GO:0003677=IEA, GO:0001701=IEA, GO:0010761=IEA, GO:0008150=ND, GO:0003674=ND, GO:0003016=IEA, GO:0005737=IEA, GO:0048745=IEA, GO:0060324=IEA, GO:0008270=IEA, GO:0048008=IEA, GO:0001944=IEA} biological_process, face development, fibroblast migration, in utero embryonic development, platelet-derived growth factor receptor signaling pathway, respiratory system process, skeletal system morphogenesis, smooth muscle tissue development, vasculature development cellular_component, cytoplasm DNA binding, molecular_function, zinc ion binding Human InterPro:IPR002653 ZFAND6 IntAct UniProtKB {GO:0005515=PMID:21810480, GO:0006625=GO_REF:0000024, GO:0006915=GO_REF:0000037, GO:0042981=PMID:21810480, GO:0005575=GO_REF:0000015, GO:0003677=GO_REF:0000002, GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000039, GO:0071356=PMID:21810480, GO:0008270=GO_REF:0000002, GO:0043122=PMID:21810480, GO:0031593=GO_REF:0000024} Q6FIF0 AN1-type zinc finger protein 6 protein 20130415 {GO:0005515=IPI, GO:0006625=ISS, GO:0006915=IEA, GO:0042981=IMP, GO:0005575=ND, GO:0003677=IEA, GO:0008150=ND, GO:0003674=ND, GO:0005737=IEA, GO:0071356=IMP, GO:0008270=IEA, GO:0043122=IMP, GO:0031593=ISS} apoptotic process, biological_process, cellular response to tumor necrosis factor, protein targeting to peroxisome, regulation of I-kappaB kinase/NF-kappaB cascade, regulation of apoptotic process cellular_component, cytoplasm DNA binding, molecular_function, polyubiquitin binding, protein binding, zinc ion binding Human UniProtKB:Q12933 ZFAT UniProtKB UniProtKB {GO:0001077=GO_REF:0000019, GO:0060712=GO_REF:0000019, GO:0002244=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0005829=GO_REF:0000039} Q9P243 Zinc finger protein ZFAT protein 20130413 {GO:0001077=IEA, GO:0060712=IEA, GO:0002244=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0005829=IEA} hematopoietic progenitor cell differentiation, spongiotrophoblast layer development cytosol, nucleus DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0091 ZFC3H1 IntAct UniProtKB {GO:0005622=GO_REF:0000002, GO:0005515=PMID:20195357, GO:0006396=GO_REF:0000002, GO:0046872=GO_REF:0000037} O60293 Zinc finger C3H1 domain-containing protein protein 20130415 {GO:0005622=IEA, GO:0005515=IPI, GO:0006396=IEA, GO:0046872=IEA} RNA processing intracellular metal ion binding, protein binding Human UniProtKB:P10242 ZFHX2 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q9C0A1 Zinc finger homeobox protein 2 protein 20130413 {GO:0043565=IEA, GO:0003700=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0006351=IEA} transcription, DNA-dependent nucleus nucleic acid binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZFHX3 PINC UniProtKB {GO:0005739=GO_REF:0000019, GO:0043565=GO_REF:0000002, GO:0005667=PMID:10318867, GO:0006355=PMID:1719379, GO:0003700=PMID:1719379, GO:0007517=GO_REF:0000037, GO:0006366=PMID:1719379, GO:0003705=PMID:1719379, GO:0005634=PMID:1719379, GO:0008270=GO_REF:0000002, GO:0000122=PMID:10318867, GO:0019899=PMID:14715251} Q15911 Zinc finger homeobox protein 3 protein 20050308 {GO:0005739=IEA, GO:0043565=IEA, GO:0005667=IDA, GO:0006355=TAS, GO:0003700=NAS, GO:0007517=IEA, GO:0006366=TAS, GO:0003705=TAS, GO:0005634=TAS, GO:0008270=IEA, GO:0000122=IGI, GO:0019899=IPI} muscle organ development, negative regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter mitochondrion, nucleus, transcription factor complex RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, enzyme binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZFHX4 UniProtKB UniProtKB {GO:0043565=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q86UP3 Zinc finger homeobox protein 4 protein 20130413 {GO:0043565=IEA, GO:0003700=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0006351=IEA} transcription, DNA-dependent nucleus sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZFP1 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6P2D0 Zinc finger protein 1 homolog protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZFP14 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9HCL3 Zinc finger protein 14 homolog protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZFP2 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6ZN57 Zinc finger protein 2 homolog protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZFP28 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8NHY6 Zinc finger protein 28 homolog protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZFP36 IntAct UniProtKB {GO:0005515=PMID:16364915, GO:0010467=Reactome:REACT_71, GO:0003727=PMID:9703499, GO:0010494=PMID:15014438, GO:0005634=PMID:10330172, GO:0003729=PMID:11782475, GO:0035925=GO_REF:0000019, GO:0007243=GO_REF:0000019, GO:0019957=PMID:21784977, GO:0005829=Reactome:REACT_25366, GO:0071889=PMID:15014438, GO:0005737=PMID:21784977, GO:0045638=GO_REF:0000019, GO:0017091=PMID:15014438, GO:0000289=GO_REF:0000019, GO:0016070=Reactome:REACT_21257, GO:0019901=PMID:15014438, GO:0016071=Reactome:REACT_20605, GO:0032680=PMID:15014438, GO:0006950=PMID:15014438, GO:0060213=PMID:10330172, GO:0003676=GO_REF:0000002, GO:0006402=PMID:11782475, GO:0003677=GO_REF:0000037, GO:0035278=GO_REF:0000024, GO:0050779=GO_REF:0000019, GO:1900153=GO_REF:0000024, GO:0050728=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0070935=PMID:15014438} P26651 Tristetraprolin protein 20130415 {GO:0005515=IPI, GO:0010467=TAS, GO:0003727=TAS, GO:0010494=IDA, GO:0005634=IDA, GO:0003729=IDA, GO:0035925=IEA, GO:0007243=IEA, GO:0019957=IPI, GO:0005829=TAS, GO:0071889=IDA, GO:0005737=IDA, GO:0045638=IEA, GO:0017091=IDA, GO:0000289=IEA, GO:0016070=TAS, GO:0019901=IPI, GO:0016071=TAS, GO:0032680=IDA, GO:0006950=IDA, GO:0060213=IDA, GO:0003676=IEA, GO:0006402=IDA, GO:0003677=IEA, GO:0035278=ISS, GO:0050779=IEA, GO:1900153=ISS, GO:0050728=IEA, GO:0008270=IEA, GO:0070935=IDA} 3'-UTR-mediated mRNA stabilization, RNA destabilization, RNA metabolic process, gene expression, intracellular protein kinase cascade, mRNA catabolic process, mRNA metabolic process, negative regulation of inflammatory response, negative regulation of myeloid cell differentiation, negative regulation of translation involved in gene silencing by miRNA, nuclear-transcribed mRNA poly(A) tail shortening, positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, positive regulation of nuclear-transcribed mRNA poly(A) tail shortening, regulation of tumor necrosis factor production, response to stress cytoplasm, cytoplasmic stress granule, cytosol, nucleus 14-3-3 protein binding, AU-rich element binding, C-C chemokine binding, DNA binding, mRNA 3'-UTR AU-rich region binding, mRNA binding, nucleic acid binding, protein binding, protein kinase binding, single-stranded RNA binding, zinc ion binding Human UniProtKB:Q9NPI6 ZFP36L1 GOC UniProtKB {GO:0005515=PMID:16189514, GO:0010467=Reactome:REACT_71, GO:0043488=PMID:15467755, GO:0006355=PMID:8595910, GO:0033077=GO_REF:0000019, GO:0003700=PMID:8595910, GO:0016070=Reactome:REACT_21257, GO:0016071=Reactome:REACT_20605, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002, GO:0003729=PMID:15467755, GO:0003677=GO_REF:0000037, GO:0006417=GO_REF:0000019, GO:0005829=Reactome:REACT_25335, GO:0005737=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0001570=GO_REF:0000019, GO:0000288=GO_REF:0000019} Q07352 Zinc finger protein 36, C3H1 type-like 1 protein 20130413 {GO:0005515=IPI, GO:0010467=TAS, GO:0043488=IDA, GO:0006355=NAS, GO:0033077=IEA, GO:0003700=NAS, GO:0016070=TAS, GO:0016071=TAS, GO:0005634=IEA, GO:0003676=IEA, GO:0003729=IDA, GO:0003677=IEA, GO:0006417=IEA, GO:0005829=TAS, GO:0005737=IEA, GO:0008270=IEA, GO:0001570=IEA, GO:0000288=IEA} RNA metabolic process, T cell differentiation in thymus, gene expression, mRNA metabolic process, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, regulation of mRNA stability, regulation of transcription, DNA-dependent, regulation of translation, vasculogenesis cytoplasm, cytosol, nucleus DNA binding, mRNA binding, nucleic acid binding, protein binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZFP36L2 GOC UniProtKB {GO:0043488=GO_REF:0000019, GO:0006355=PMID:7835719, GO:0005737=GO_REF:0000019, GO:0003700=PMID:7835719, GO:0008283=PMID:7835719, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0000288=GO_REF:0000019} P47974 Zinc finger protein 36, C3H1 type-like 2 protein 20130413 {GO:0043488=IEA, GO:0006355=TAS, GO:0005737=IEA, GO:0003700=TAS, GO:0008283=TAS, GO:0003723=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0000288=IEA} cell proliferation, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, regulation of mRNA stability, regulation of transcription, DNA-dependent cytoplasm, nucleus DNA binding, RNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZFP37 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=PMID:9585434, GO:0003700=PMID:9585434, GO:0005634=GO_REF:0000029, GO:0008270=PMID:9585434, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9Y6Q3 Zinc finger protein 37 homolog protein 20010905 {GO:0005622=IEA, GO:0006355=NAS, GO:0003700=NAS, GO:0005634=NAS, GO:0008270=NAS, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZFP42 UniProtKB UniProtKB {GO:0008585=PMID:18281244, GO:0005737=PMID:18281244, GO:2000653=GO_REF:0000019, GO:0007126=PMID:18281244, GO:0003700=PMID:14688391, GO:0007286=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0001701=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0008584=PMID:18281244, GO:0006351=GO_REF:0000037} Q96MM3 Zinc finger protein 42 homolog protein 20080310 {GO:0008585=IEP, GO:0005737=IDA, GO:2000653=IEA, GO:0007126=NAS, GO:0003700=NAS, GO:0007286=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0001701=IEA, GO:0003677=IEA, GO:0008584=IEP, GO:0006351=IEA} female gonad development, in utero embryonic development, male gonad development, meiosis, regulation of genetic imprinting, spermatid development, transcription, DNA-dependent cytoplasm, nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZFP62 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q8NB50 Zinc finger protein 62 homolog protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZFP64 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9NTW7 Zinc finger protein 64 homolog, isoforms 3 and 4 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZFP82 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8N141 Zinc finger protein 82 homolog protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZFP91 HPA UniProtKB {GO:0004842=PMID:20682767, GO:0070534=PMID:20682767, GO:0007250=PMID:20682767, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0043231=GO_REF:0000052} Q96JP5 E3 ubiquitin-protein ligase ZFP91 protein 20101115 {GO:0004842=IDA, GO:0070534=IDA, GO:0007250=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003676=IEA, GO:0043231=IDA} activation of NF-kappaB-inducing kinase activity, protein K63-linked ubiquitination intracellular membrane-bounded organelle, nucleolus, nucleus nucleic acid binding, ubiquitin-protein ligase activity, zinc ion binding Human ZFPL1 HPA UniProtKB {GO:0006355=PMID:9653652, GO:0005794=GO_REF:0000052, GO:0005634=PMID:9653652, GO:0008270=PMID:9653652, GO:0016021=GO_REF:0000037, GO:0016192=GO_REF:0000037, GO:0003677=PMID:9653652} O95159 Zinc finger protein-like 1 protein 20090616 {GO:0006355=NAS, GO:0005794=IDA, GO:0005634=NAS, GO:0008270=NAS, GO:0016021=IEA, GO:0016192=IEA, GO:0003677=NAS} regulation of transcription, DNA-dependent, vesicle-mediated transport Golgi apparatus, integral to membrane, nucleus DNA binding, zinc ion binding Human ZFPM1 BHF-UCL UniProtKB {GO:0005515=PMID:21988832, GO:0032091=GO_REF:0000024, GO:0071733=GO_REF:0000024, GO:0003181=GO_REF:0000024, GO:0045599=GO_REF:0000024, GO:0045403=PMID:21646796, GO:0060318=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0060319=GO_REF:0000019, GO:0045078=PMID:21646796, GO:0017053=PMID:15920471, GO:0060377=GO_REF:0000024, GO:0001085=PMID:15920471, GO:0032642=GO_REF:0000019, GO:0030851=GO_REF:0000019, GO:0035162=GO_REF:0000024, GO:0030220=PMID:11675338, GO:0055008=GO_REF:0000024, GO:0005667=PMID:15920471, GO:0001102=GO_REF:0000019, GO:0060413=GO_REF:0000024, GO:0060412=GO_REF:0000024, GO:0003195=GO_REF:0000024, GO:0003192=GO_REF:0000024, GO:0003677=GO_REF:0000037, GO:0003151=GO_REF:0000024, GO:0010724=PMID:17207461, GO:0001078=PMID:15920471, GO:0035855=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0030219=GO_REF:0000024, GO:0030218=GO_REF:0000024, GO:0002295=PMID:21646796, GO:0005654=Reactome:REACT_25215, GO:0008270=GO_REF:0000002, GO:0008134=PMID:12483298} Q8IX07 Zinc finger protein ZFPM1 protein 20110811 {GO:0005515=IPI, GO:0032091=ISS, GO:0071733=ISS, GO:0003181=ISS, GO:0045599=ISS, GO:0045403=IDA, GO:0060318=IEA, GO:0005737=IEA, GO:0060319=IEA, GO:0045078=IDA, GO:0017053=IDA, GO:0060377=ISS, GO:0001085=IPI, GO:0032642=IEA, GO:0030851=IEA, GO:0035162=ISS, GO:0030220=IGI, GO:0055008=ISS, GO:0005667=IDA, GO:0001102=IEA, GO:0060413=ISS, GO:0060412=ISS, GO:0003195=ISS, GO:0003192=ISS, GO:0003677=IEA, GO:0003151=ISS, GO:0010724=IMP, GO:0001078=IDA, GO:0035855=IEA, GO:0007596=TAS, GO:0030219=ISS, GO:0030218=ISS, GO:0002295=IC, GO:0005654=TAS, GO:0008270=IEA, GO:0008134=IPI} T-helper cell lineage commitment, atrial septum morphogenesis, atrioventricular valve morphogenesis, blood coagulation, cardiac muscle tissue morphogenesis, definitive erythrocyte differentiation, embryonic hemopoiesis, erythrocyte differentiation, granulocyte differentiation, megakaryocyte development, megakaryocyte differentiation, mitral valve formation, negative regulation of fat cell differentiation, negative regulation of interleukin-4 biosynthetic process, negative regulation of mast cell differentiation, negative regulation of protein binding, outflow tract morphogenesis, platelet formation, positive regulation of interferon-gamma biosynthetic process, primitive erythrocyte differentiation, regulation of chemokine production, regulation of definitive erythrocyte differentiation, transcriptional activation by promoter-enhancer looping, tricuspid valve formation, ventricular septum morphogenesis cytoplasm, nucleoplasm, transcription factor complex, transcriptional repressor complex DNA binding, RNA polymerase II activating transcription factor binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, RNA polymerase II transcription factor binding, protein binding, transcription factor binding, zinc ion binding Human ZFPM2 BHF-UCL UniProtKB {GO:0005515=PMID:10438528, GO:0045599=PMID:20705609, GO:0030324=GO_REF:0000019, GO:0005634=GO_REF:0000019, GO:0005737=GO_REF:0000019, GO:0003221=PMID:20807224, GO:0048568=GO_REF:0000019, GO:0045944=PMID:10438528, GO:0060548=GO_REF:0000019, GO:2000195=GO_REF:0000019, GO:0001105=PMID:10438528, GO:0003714=PMID:10438528, GO:0060412=PMID:20807224, GO:0000122=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0001701=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0048738=GO_REF:0000019, GO:0007596=Reactome:REACT_604, GO:0003148=PMID:20807224, GO:0001071=GO_REF:0000019, GO:0008270=PMID:10438528, GO:0005654=Reactome:REACT_25215, GO:0001570=GO_REF:0000019, GO:0045892=PMID:20206639, GO:0008134=PMID:10438528, GO:2000020=GO_REF:0000019} Q8WW38 Zinc finger protein ZFPM2 protein 20110512 {GO:0005515=IPI, GO:0045599=IMP, GO:0030324=IEA, GO:0005634=IEA, GO:0005737=IEA, GO:0003221=IMP, GO:0048568=IEA, GO:0045944=IDA, GO:0060548=IEA, GO:2000195=IEA, GO:0001105=NAS, GO:0003714=IDA, GO:0060412=IMP, GO:0000122=IEA, GO:0003676=IEA, GO:0001701=IEA, GO:0003677=IEA, GO:0048738=IEA, GO:0007596=TAS, GO:0003148=IMP, GO:0001071=IEA, GO:0008270=NAS, GO:0005654=TAS, GO:0001570=IEA, GO:0045892=IDA, GO:0008134=IPI, GO:2000020=IEA} blood coagulation, cardiac muscle tissue development, embryonic organ development, in utero embryonic development, lung development, negative regulation of cell death, negative regulation of fat cell differentiation, negative regulation of female gonad development, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, outflow tract septum morphogenesis, positive regulation of male gonad development, positive regulation of transcription from RNA polymerase II promoter, right ventricular cardiac muscle tissue morphogenesis, vasculogenesis, ventricular septum morphogenesis cytoplasm, nucleoplasm, nucleus DNA binding, RNA polymerase II transcription coactivator activity, nucleic acid binding, nucleic acid binding transcription factor activity, protein binding, transcription corepressor activity, transcription factor binding, zinc ion binding Human ZFR HPA UniProtKB {GO:0005515=PMID:20195357, GO:0005737=GO_REF:0000039, GO:0005694=GO_REF:0000039, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0007275=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037} Q96KR1 Zinc finger RNA-binding protein protein 20090616 {GO:0005515=IPI, GO:0005737=IEA, GO:0005694=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0007275=IEA, GO:0008270=IEA, GO:0003677=IEA} multicellular organismal development chromosome, cytoplasm, nucleolus, nucleus DNA binding, RNA binding, protein binding, zinc ion binding NOT Human ZFX HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0003713=PMID:2105457, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0046872=GO_REF:0000002} P17010 Zinc finger X-chromosomal protein protein 20101115 {GO:0006355=IEA, GO:0003713=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0046872=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus, nucleus DNA binding, metal ion binding, transcription coactivator activity, zinc ion binding NOT Human ZFY UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P08048 Zinc finger Y-chromosomal protein protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZFYVE1 IntAct UniProtKB {GO:0005515=PMID:19389623, GO:0005545=PMID:11256955, GO:0048471=PMID:11739631, GO:0005795=PMID:11256955, GO:0005783=PMID:11739631, GO:0010923=PMID:19389623, GO:0043325=PMID:11804589, GO:0005547=PMID:11804589, GO:0008270=PMID:11739631, GO:0046872=GO_REF:0000038} Q9HBF4 Zinc finger FYVE domain-containing protein 1 protein 20130415 {GO:0005515=IPI, GO:0005545=IDA, GO:0048471=IDA, GO:0005795=IDA, GO:0005783=IDA, GO:0010923=IDA, GO:0043325=IDA, GO:0005547=IDA, GO:0008270=NAS, GO:0046872=IEA} negative regulation of phosphatase activity Golgi stack, endoplasmic reticulum, perinuclear region of cytoplasm 1-phosphatidylinositol binding, metal ion binding, phosphatidylinositol-3,4,5-trisphosphate binding, phosphatidylinositol-3,4-bisphosphate binding, protein binding, zinc ion binding Human UniProtKB:P62136 ZFYVE16 HPA UniProtKB {GO:0005515=PMID:14613930, GO:0005547=PMID:11433298, GO:0030509=Reactome:REACT_12034, GO:0046872=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0005545=PMID:11546807, GO:0007165=PMID:11546807, GO:0016050=PMID:11546807, GO:0005737=GO_REF:0000052, GO:0030100=PMID:11546807, GO:0031901=Reactome:REACT_12069, GO:0008565=PMID:11546807, GO:0016197=PMID:11546807, GO:0006622=PMID:11546807, GO:0005769=PMID:11546807} Q7Z3T8 Zinc finger FYVE domain-containing protein 16 protein 20110516 {GO:0005515=IPI, GO:0005547=IDA, GO:0030509=TAS, GO:0046872=IEA, GO:0043231=IDA, GO:0005545=IDA, GO:0007165=NAS, GO:0016050=NAS, GO:0005737=IDA, GO:0030100=TAS, GO:0031901=TAS, GO:0008565=IMP, GO:0016197=IMP, GO:0006622=IMP, GO:0005769=IDA} BMP signaling pathway, endosomal transport, protein targeting to lysosome, regulation of endocytosis, signal transduction, vesicle organization cytoplasm, early endosome, early endosome membrane, intracellular membrane-bounded organelle 1-phosphatidylinositol binding, metal ion binding, phosphatidylinositol-3,4,5-trisphosphate binding, protein binding, protein transporter activity Human ZFYVE19 InterPro UniProtKB {GO:0008270=GO_REF:0000002} Q96K21 Zinc finger FYVE domain-containing protein 19 protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR001841 ZFYVE20 HPA UniProtKB {GO:0005515=PMID:16034420, GO:0017137=GO_REF:0000019, GO:0005886=GO_REF:0000039, GO:0007596=Reactome:REACT_604, GO:0031901=GO_REF:0000039, GO:0016197=PMID:11062261, GO:0008270=PMID:11062261, GO:0015031=GO_REF:0000037, GO:0010008=Reactome:REACT_25249, GO:0043231=GO_REF:0000052, GO:0005768=PMID:11062261} Q9H1K0 Rabenosyn-5 protein 20111111 {GO:0005515=IPI, GO:0017137=IEA, GO:0005886=IEA, GO:0007596=TAS, GO:0031901=IEA, GO:0016197=NAS, GO:0008270=NAS, GO:0015031=IEA, GO:0010008=TAS, GO:0043231=IDA, GO:0005768=NAS} blood coagulation, endosomal transport, protein transport early endosome membrane, endosome, endosome membrane, intracellular membrane-bounded organelle, plasma membrane Rab GTPase binding, protein binding, zinc ion binding Human ZFYVE21 UniProtKB UniProtKB {GO:0016023=GO_REF:0000039, GO:0005925=GO_REF:0000039, GO:0046872=GO_REF:0000037} Q9BQ24 Zinc finger FYVE domain-containing protein 21 protein 20130413 {GO:0016023=IEA, GO:0005925=IEA, GO:0046872=IEA} cytoplasmic membrane-bounded vesicle, focal adhesion metal ion binding Human UniProtKB-SubCell:SL-0088 ZFYVE26 UniProtKB UniProtKB {GO:0005515=PMID:20208530, GO:0000910=PMID:20208530, GO:0008219=GO_REF:0000037, GO:0005813=PMID:20208530, GO:0007049=GO_REF:0000037, GO:0005737=GO_REF:0000037, GO:0000724=PMID:20613862, GO:0030496=PMID:20208530, GO:0032266=PMID:20208530, GO:0046872=GO_REF:0000037} Q68DK2 Zinc finger FYVE domain-containing protein 26 protein 20110317 {GO:0005515=IPI, GO:0000910=IMP, GO:0008219=IEA, GO:0005813=IDA, GO:0007049=IEA, GO:0005737=IEA, GO:0000724=IMP, GO:0030496=IDA, GO:0032266=IDA, GO:0046872=IEA} cell cycle, cell death, cytokinesis, double-strand break repair via homologous recombination centrosome, cytoplasm, midbody metal ion binding, phosphatidylinositol-3-phosphate binding, protein binding Human ZFYVE27 IntAct UniProtKB {GO:0005515=PMID:19289470, GO:0008219=GO_REF:0000037, GO:0030424=GO_REF:0000024, GO:0048011=GO_REF:0000024, GO:0005783=PMID:19289470, GO:0032584=GO_REF:0000024, GO:0072659=GO_REF:0000024, GO:0046872=GO_REF:0000037, GO:0031175=PMID:17082457, GO:0030425=GO_REF:0000024, GO:0005789=GO_REF:0000039, GO:0016021=GO_REF:0000037, GO:0055038=GO_REF:0000024} Q5T4F4 Protrudin protein 20130415 {GO:0005515=IPI, GO:0008219=IEA, GO:0030424=ISS, GO:0048011=ISS, GO:0005783=IDA, GO:0032584=ISS, GO:0072659=ISS, GO:0046872=IEA, GO:0031175=IDA, GO:0030425=ISS, GO:0005789=IEA, GO:0016021=IEA, GO:0055038=ISS} cell death, neuron projection development, neurotrophin TRK receptor signaling pathway, protein localization to plasma membrane axon, dendrite, endoplasmic reticulum, endoplasmic reticulum membrane, growth cone membrane, integral to membrane, recycling endosome membrane metal ion binding, protein binding Human UniProtKB:Q9P0L0 ZFYVE28 UniProtKB UniProtKB {GO:0005515=PMID:19460345, GO:0031901=PMID:19460345, GO:0007175=PMID:19460345, GO:0042059=PMID:19460345, GO:0032266=PMID:19460345, GO:0046872=GO_REF:0000037, GO:0005829=PMID:19460345} Q9HCC9 Lateral signaling target protein 2 homolog protein 20090524 {GO:0005515=IPI, GO:0031901=IDA, GO:0007175=IMP, GO:0042059=IMP, GO:0032266=IDA, GO:0046872=IEA, GO:0005829=IDA} negative regulation of epidermal growth factor receptor signaling pathway, negative regulation of epidermal growth factor-activated receptor activity cytosol, early endosome membrane metal ion binding, phosphatidylinositol-3-phosphate binding, protein binding Human ZFYVE9 IntAct UniProtKB {GO:0005515=PMID:17693260, GO:0005545=PMID:11877415, GO:0007183=PMID:9865696, GO:0005737=GO_REF:0000029, GO:0031901=Reactome:REACT_121180, GO:0007184=PMID:9865696, GO:0008236=PMID:9582421, GO:0007179=Reactome:REACT_120850, GO:0030512=Reactome:REACT_120727, GO:0005769=PMID:12809483, GO:0046872=GO_REF:0000037, GO:0006897=PMID:12809483} O95405 Zinc finger FYVE domain-containing protein 9 protein 20130415 {GO:0005515=IPI, GO:0005545=IDA, GO:0007183=IDA, GO:0005737=NAS, GO:0031901=TAS, GO:0007184=IMP, GO:0008236=NAS, GO:0007179=TAS, GO:0030512=TAS, GO:0005769=NAS, GO:0046872=IEA, GO:0006897=NAS} SMAD protein complex assembly, SMAD protein import into nucleus, endocytosis, negative regulation of transforming growth factor beta receptor signaling pathway, transforming growth factor beta receptor signaling pathway cytoplasm, early endosome, early endosome membrane 1-phosphatidylinositol binding, metal ion binding, protein binding, serine-type peptidase activity Human UniProtKB:P08100 ZG16 UniProtKB UniProtKB {GO:0031012=PMID:17307141, GO:0042589=GO_REF:0000019, GO:0005796=PMID:17307141, GO:0005578=GO_REF:0000039, GO:0015031=PMID:17307141, GO:0060205=GO_REF:0000039} O60844 Zymogen granule membrane protein 16 protein 20110202 {GO:0031012=IDA, GO:0042589=IEA, GO:0005796=IDA, GO:0005578=IEA, GO:0015031=TAS, GO:0060205=IEA} protein transport Golgi lumen, cytoplasmic membrane-bounded vesicle lumen, extracellular matrix, proteinaceous extracellular matrix, zymogen granule membrane Human ZG16B UniProtKB UniProtKB {GO:0005576=GO_REF:0000039} Q96DA0 Zymogen granule protein 16 homolog B protein 20130413 {GO:0005576=IEA} extracellular region Human UniProtKB-SubCell:SL-0243 ZGPAT UniProtKB UniProtKB {GO:0005515=PMID:19644445, GO:0043565=PMID:19644445, GO:0003700=PMID:19644445, GO:0007175=PMID:19644445, GO:0005634=PMID:19644445, GO:0008270=GO_REF:0000002, GO:0045892=PMID:19644445, GO:0006351=GO_REF:0000037} Q8N5A5 Zinc finger CCCH-type with G patch domain-containing protein protein 20090807 {GO:0005515=IPI, GO:0043565=IDA, GO:0003700=IDA, GO:0007175=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0045892=IDA, GO:0006351=IEA} negative regulation of epidermal growth factor-activated receptor activity, negative regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZHX1 IntAct UniProtKB {GO:0005515=PMID:16713569, GO:0043565=GO_REF:0000002, GO:0003700=PMID:12237128, GO:0046982=PMID:12659632, GO:0003714=PMID:17303076, GO:0008270=GO_REF:0000002, GO:0005634=PMID:17056598, GO:0000122=PMID:17303076, GO:0045892=PMID:12237128, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9UKY1 Zinc fingers and homeoboxes protein 1 protein 20130415 {GO:0005515=IPI, GO:0043565=IEA, GO:0003700=IDA, GO:0046982=IDA, GO:0003714=IDA, GO:0008270=IEA, GO:0005634=IDA, GO:0000122=IDA, GO:0045892=IDA, GO:0030154=IEA, GO:0006351=IEA} cell differentiation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus protein binding, protein heterodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity, zinc ion binding Human UniProtKB:P54253 ZHX2 HPA UniProtKB {GO:0005515=PMID:12741956, GO:0003700=PMID:12741956, GO:0005886=GO_REF:0000052, GO:0046982=PMID:12741956, GO:0003714=PMID:12741956, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000122=PMID:12741956, GO:0006402=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0042803=PMID:12741956, GO:0043565=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0045665=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0035019=GO_REF:0000019, GO:0045892=PMID:12741956} Q9Y6X8 Zinc fingers and homeoboxes protein 2 protein 20101115 {GO:0005515=IPI, GO:0003700=IDA, GO:0005886=IDA, GO:0046982=IDA, GO:0003714=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0000122=IDA, GO:0006402=IEA, GO:0006351=IEA, GO:0042803=IDA, GO:0043565=IEA, GO:0005737=IDA, GO:0045665=IEA, GO:0008270=IEA, GO:0035019=IEA, GO:0045892=IDA} mRNA catabolic process, negative regulation of neuron differentiation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, somatic stem cell maintenance, transcription, DNA-dependent cytoplasm, nucleolus, nucleus, plasma membrane protein binding, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity, zinc ion binding Human ZHX3 HPA UniProtKB {GO:0005515=PMID:12659632, GO:0003700=PMID:12659632, GO:0046982=PMID:12659632, GO:0003714=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000122=GO_REF:0000019, GO:0042803=PMID:12659632, GO:0006351=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0046872=GO_REF:0000037, GO:0045669=PMID:21174497, GO:0043565=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0045892=PMID:12659632} Q9H4I2 Zinc fingers and homeoboxes protein 3 protein 20101115 {GO:0005515=IPI, GO:0003700=IDA, GO:0046982=IDA, GO:0003714=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0000122=IEA, GO:0042803=IDA, GO:0006351=IEA, GO:0030154=IEA, GO:0046872=IEA, GO:0045669=IMP, GO:0043565=IEA, GO:0005737=IDA, GO:0045892=IDA} cell differentiation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of osteoblast differentiation, transcription, DNA-dependent cytoplasm, nucleolus, nucleus metal ion binding, protein binding, protein heterodimerization activity, protein homodimerization activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity Human ZIC1 HPA UniProtKB {GO:0007389=GO_REF:0000024, GO:0042472=GO_REF:0000024, GO:0003700=GO_REF:0000024, GO:0021510=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0005737=GO_REF:0000039, GO:0008589=GO_REF:0000024, GO:0007420=PMID:8542595, GO:0042307=GO_REF:0000024, GO:0007610=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0045893=GO_REF:0000024} Q15915 Zinc finger protein ZIC 1 protein 20101115 {GO:0007389=ISS, GO:0042472=ISS, GO:0003700=ISS, GO:0021510=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0030154=IEA, GO:0005737=IEA, GO:0008589=ISS, GO:0007420=IDA, GO:0042307=ISS, GO:0007610=ISS, GO:0008270=IEA, GO:0045893=ISS} behavior, brain development, cell differentiation, inner ear morphogenesis, pattern specification process, positive regulation of protein import into nucleus, positive regulation of transcription, DNA-dependent, regulation of smoothened signaling pathway, spinal cord development, transcription, DNA-dependent cytoplasm, nucleolus, nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding transcription factor activity, zinc ion binding NOT Human ZIC2 UniProtKB UniProtKB {GO:0031290=GO_REF:0000019, GO:0003700=GO_REF:0000024, GO:0001843=GO_REF:0000019, GO:0005634=GO_REF:0000024, GO:0003677=GO_REF:0000024, GO:0031490=GO_REF:0000024, GO:0006351=GO_REF:0000037, GO:0051091=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0007420=PMID:9771712, GO:0008270=GO_REF:0000002, GO:0045893=GO_REF:0000024, GO:0007601=GO_REF:0000024, GO:0045892=GO_REF:0000024, GO:0048066=GO_REF:0000019} O95409 Zinc finger protein ZIC 2 protein 20110203 {GO:0031290=IEA, GO:0003700=ISS, GO:0001843=IEA, GO:0005634=ISS, GO:0003677=ISS, GO:0031490=ISS, GO:0006351=IEA, GO:0051091=ISS, GO:0005737=ISS, GO:0007420=TAS, GO:0008270=IEA, GO:0045893=ISS, GO:0007601=ISS, GO:0045892=ISS, GO:0048066=IEA} brain development, developmental pigmentation, negative regulation of transcription, DNA-dependent, neural tube closure, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of transcription, DNA-dependent, retinal ganglion cell axon guidance, transcription, DNA-dependent, visual perception cytoplasm, nucleus DNA binding, chromatin DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB:Q62520 ZIC3 BHF-UCL UniProtKB {GO:0005515=PMID:17764085, GO:0007368=PMID:9354794, GO:0035469=PMID:9354794, GO:0003700=PMID:17764085, GO:0071910=PMID:9354794, GO:0030324=PMID:9354794, GO:0005634=GO_REF:0000024, GO:0009952=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0043565=PMID:17764085, GO:0001947=PMID:9354794, GO:0035545=GO_REF:0000019, GO:0005737=GO_REF:0000024, GO:0045944=PMID:17764085, GO:0008270=GO_REF:0000002, GO:0045893=GO_REF:0000024, GO:0071907=PMID:9354794} O60481 Zinc finger protein ZIC 3 protein 20120517 {GO:0005515=IPI, GO:0007368=IMP, GO:0035469=IMP, GO:0003700=IDA, GO:0071910=IMP, GO:0030324=IMP, GO:0005634=ISS, GO:0009952=IEA, GO:0006351=IEA, GO:0030154=IEA, GO:0043565=IDA, GO:0001947=IMP, GO:0035545=IEA, GO:0005737=ISS, GO:0045944=IDA, GO:0008270=IEA, GO:0045893=ISS, GO:0071907=IMP} anterior/posterior pattern specification, cell differentiation, determination of digestive tract left/right asymmetry, determination of left/right asymmetry in nervous system, determination of left/right symmetry, determination of liver left/right asymmetry, determination of pancreatic left/right asymmetry, heart looping, lung development, positive regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZIC4 UniProtKB UniProtKB {GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000024, GO:0003677=GO_REF:0000024} Q8N9L1 Zinc finger protein ZIC 4 protein 20110207 {GO:0008270=IEA, GO:0005634=ISS, GO:0003677=ISS} nucleus DNA binding, zinc ion binding Human UniProtKB:Q61467 ZIC5 UniProtKB UniProtKB {GO:0003700=GO_REF:0000019, GO:0001843=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0030900=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0030154=GO_REF:0000019} Q96T25 Zinc finger protein ZIC 5 protein 20130413 {GO:0003700=IEA, GO:0001843=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0030900=IEA, GO:0003677=IEA, GO:0030154=IEA} cell differentiation, forebrain development, neural tube closure nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZIK1 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q3SY52 Zinc finger protein interacting with ribonucleoprotein K protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZIM3 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96PE6 Zinc finger imprinted 3 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZKSCAN1 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0006355=PMID:7557990, GO:0003700=PMID:7557990, GO:0016032=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P17029 Zinc finger protein with KRAB and SCAN domains 1 protein 20101115 {GO:0005739=IDA, GO:0006355=NAS, GO:0003700=NAS, GO:0016032=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent, viral reproduction mitochondrion, nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZKSCAN4 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0016032=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q969J2 Zinc finger protein with KRAB and SCAN domains 4 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0003700=IEA, GO:0016032=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent, viral reproduction intracellular, nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZKSCAN5 UniProtKB UniProtKB {GO:0006355=PMID:10585779, GO:0003700=PMID:10585779, GO:0016032=GO_REF:0000002, GO:0008270=PMID:10585779, GO:0005634=PMID:10585779, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9Y2L8 Zinc finger protein with KRAB and SCAN domains 5 protein 20010912 {GO:0006355=NAS, GO:0003700=NAS, GO:0016032=IEA, GO:0008270=NAS, GO:0005634=NAS, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent, viral reproduction nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZMAT2 IntAct UniProtKB {GO:0005515=PMID:23275563, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037} Q96NC0 Zinc finger matrin-type protein 2 protein 20130415 {GO:0005515=IPI, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA} nucleus DNA binding, protein binding, zinc ion binding Human UniProtKB:P42858 ZMAT3 UniProtKB UniProtKB {GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0006915=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0006917=GO_REF:0000019, GO:0015031=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0040008=GO_REF:0000037, GO:0006974=GO_REF:0000037} Q9HA38 Zinc finger matrin-type protein 3 protein 20130413 {GO:0003723=IEA, GO:0005730=IEA, GO:0006915=IEA, GO:0008270=IEA, GO:0006917=IEA, GO:0015031=IEA, GO:0003676=IEA, GO:0040008=IEA, GO:0006974=IEA} apoptotic process, induction of apoptosis, protein transport, regulation of growth, response to DNA damage stimulus nucleolus RNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0188 ZMAT4 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037} Q9H898 Zinc finger matrin-type protein 4 protein 20130413 {GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA} nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZMAT5 HPA UniProtKB {GO:0008380=PMID:15146077, GO:0006397=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0005689=PMID:15146077} Q9UDW3 Zinc finger matrin-type protein 5 protein 20080818 {GO:0008380=IC, GO:0006397=IEA, GO:0005737=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003676=IEA, GO:0005689=IDA} RNA splicing, mRNA processing U12-type spliceosomal complex, cytoplasm, nucleolus, nucleus nucleic acid binding, zinc ion binding Human ZMIZ1 UniProtKB UniProtKB {GO:0007569=GO_REF:0000019, GO:0048844=GO_REF:0000019, GO:0048146=GO_REF:0000019, GO:0001701=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0007296=GO_REF:0000019, GO:0003007=GO_REF:0000019, GO:0005737=GO_REF:0000039, GO:0048589=GO_REF:0000019, GO:0016607=GO_REF:0000039, GO:0045944=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0001570=GO_REF:0000019} Q9ULJ6 Zinc finger MIZ domain-containing protein 1 protein 20130413 {GO:0007569=IEA, GO:0048844=IEA, GO:0048146=IEA, GO:0001701=IEA, GO:0006351=IEA, GO:0007296=IEA, GO:0003007=IEA, GO:0005737=IEA, GO:0048589=IEA, GO:0016607=IEA, GO:0045944=IEA, GO:0008270=IEA, GO:0001570=IEA} artery morphogenesis, cell aging, developmental growth, heart morphogenesis, in utero embryonic development, positive regulation of fibroblast proliferation, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent, vasculogenesis, vitellogenesis cytoplasm, nuclear speck zinc ion binding Human UniProtKB-SubCell:SL-0186 ZMIZ2 HPA UniProtKB {GO:0005515=PMID:16051670, GO:0005739=GO_REF:0000052, GO:0030374=PMID:16051670, GO:0045944=PMID:16051670, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0043596=PMID:16051670, GO:0006351=GO_REF:0000037} Q8NF64 Zinc finger MIZ domain-containing protein 2 protein 20110516 {GO:0005515=IPI, GO:0005739=IDA, GO:0030374=IDA, GO:0045944=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0043596=IDA, GO:0006351=IEA} positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent mitochondrion, nuclear replication fork, nucleolus, nucleus ligand-dependent nuclear receptor transcription coactivator activity, protein binding, zinc ion binding Human ZMPSTE24 PINC UniProtKB {GO:0000139=GO_REF:0000039, GO:0008235=PMID:10373325, GO:0006508=PMID:10373325, GO:0005789=GO_REF:0000039, GO:0071586=GO_REF:0000002, GO:0030327=GO_REF:0000019, GO:0006998=GO_REF:0000019, GO:0016021=GO_REF:0000037, GO:0004222=GO_REF:0000019, GO:0046872=GO_REF:0000037} O75844 CAAX prenyl protease 1 homolog protein 20030904 {GO:0000139=IEA, GO:0008235=TAS, GO:0006508=TAS, GO:0005789=IEA, GO:0071586=IEA, GO:0030327=IEA, GO:0006998=IEA, GO:0016021=IEA, GO:0004222=IEA, GO:0046872=IEA} CAAX-box protein processing, nuclear envelope organization, prenylated protein catabolic process, proteolysis Golgi membrane, endoplasmic reticulum membrane, integral to membrane metal ion binding, metalloendopeptidase activity, metalloexopeptidase activity Human ZMYM1 InterPro UniProtKB {GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q5SW02 Zinc finger MYM-type protein 1 protein 20130413 {GO:0046983=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA} nucleus nucleic acid binding, protein dimerization activity, zinc ion binding Human InterPro:IPR008906 ZMYM2 Reactome UniProtKB {GO:0008150=GO_REF:0000015, GO:0006355=GO_REF:0000037, GO:0016605=PMID:17027752, GO:0008270=PMID:9576949, GO:0006351=GO_REF:0000037, GO:0005829=Reactome:REACT_121382, GO:0031624=PMID:12776193} Q9UBW7 Zinc finger MYM-type protein 2 protein 20121108 {GO:0008150=ND, GO:0006355=IEA, GO:0016605=IDA, GO:0008270=NAS, GO:0006351=IEA, GO:0005829=TAS, GO:0031624=IPI} biological_process, regulation of transcription, DNA-dependent, transcription, DNA-dependent PML body, cytosol ubiquitin conjugating enzyme binding, zinc ion binding Human ZMYM3 PINC UniProtKB {GO:0022604=PMID:21834987, GO:0007010=PMID:21834987, GO:0007275=PMID:10486218, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=PMID:10486218} Q14202 Zinc finger MYM-type protein 3 protein 20030904 {GO:0022604=IMP, GO:0007010=IMP, GO:0007275=TAS, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=TAS} cytoskeleton organization, multicellular organismal development, regulation of cell morphogenesis nucleus DNA binding, zinc ion binding Human ZMYM4 PINC UniProtKB {GO:0022604=PMID:21834987, GO:0007010=PMID:21834987, GO:0007275=PMID:10486218, GO:0008270=GO_REF:0000002, GO:0003677=PMID:10486218} Q5VZL5 Zinc finger MYM-type protein 4 protein 20070906 {GO:0022604=IMP, GO:0007010=IMP, GO:0007275=TAS, GO:0008270=IEA, GO:0003677=TAS} cytoskeleton organization, multicellular organismal development, regulation of cell morphogenesis DNA binding, zinc ion binding Human ZMYM5 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002} Q9UJ78 Zinc finger MYM-type protein 5 protein 20130413 {GO:0005634=IEA, GO:0008270=IEA} nucleus zinc ion binding Human UniProtKB-SubCell:SL-0191 ZMYM6 PINC UniProtKB {GO:0022604=PMID:21834987, GO:0007010=PMID:21834987, GO:0007275=PMID:10486218, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=PMID:10486218} O95789 Zinc finger MYM-type protein 6 protein 20030904 {GO:0022604=IMP, GO:0007010=IMP, GO:0007275=TAS, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=TAS} cytoskeleton organization, multicellular organismal development, regulation of cell morphogenesis nucleus DNA binding, zinc ion binding Human ZMYM6NB UniProtKB UniProtKB {GO:0016021=GO_REF:0000037} Q8NCS4 Uncharacterized protein ZMYM6NB protein 20130413 {GO:0016021=IEA} integral to membrane Human UniProtKB-KW:KW-0812 ZMYND10 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0005737=GO_REF:0000054, GO:0008270=GO_REF:0000002} O75800 Zinc finger MYND domain-containing protein 10 protein 20130415 {GO:0005515=IPI, GO:0005737=IDA, GO:0008270=IEA} cytoplasm protein binding, zinc ion binding Human UniProtKB:Q9Y3Q8 ZMYND11 HPA UniProtKB {GO:0005515=PMID:20732415, GO:2001237=PMID:20732415, GO:0008283=PMID:7621829, GO:0005694=GO_REF:0000039, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000122=PMID:7621829, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0007049=GO_REF:0000037, GO:0046329=PMID:20732415, GO:0019048=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0016568=GO_REF:0000037, GO:0043124=PMID:20732415} Q5VUI0 Zinc finger MYND domain-containing protein 11 protein 20110516 {GO:0005515=IPI, GO:2001237=IMP, GO:0008283=TAS, GO:0005694=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0000122=TAS, GO:0003677=IEA, GO:0006351=IEA, GO:0005737=IDA, GO:0007049=IEA, GO:0046329=IMP, GO:0019048=IEA, GO:0008270=IEA, GO:0016568=IEA, GO:0043124=IMP} cell cycle, cell proliferation, chromatin modification, negative regulation of I-kappaB kinase/NF-kappaB cascade, negative regulation of JNK cascade, negative regulation of extrinsic apoptotic signaling pathway, negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent, virus-host interaction chromosome, cytoplasm, nucleolus, nucleus DNA binding, protein binding, zinc ion binding Human ZMYND19 HPA UniProtKB {GO:0005794=GO_REF:0000052, GO:0005886=GO_REF:0000039, GO:0045202=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0043231=GO_REF:0000052} Q96E35 Zinc finger MYND domain-containing protein 19 protein 20100326 {GO:0005794=IDA, GO:0005886=IEA, GO:0045202=IEA, GO:0008270=IEA, GO:0043231=IDA} Golgi apparatus, intracellular membrane-bounded organelle, plasma membrane, synapse zinc ion binding Human ZMYND8 GOC UniProtKB {GO:0005515=PMID:15095401, GO:0001106=GO_REF:0000024, GO:0016301=GO_REF:0000038, GO:0070491=GO_REF:0000024, GO:0005634=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0000122=GO_REF:0000024} Q9ULU4 Protein kinase C-binding protein 1 protein 20130413 {GO:0005515=IPI, GO:0001106=ISS, GO:0016301=IEA, GO:0070491=ISS, GO:0005634=ISS, GO:0008270=IEA, GO:0000122=ISS} negative regulation of transcription from RNA polymerase II promoter nucleus RNA polymerase II transcription corepressor activity, kinase activity, protein binding, repressing transcription factor binding, zinc ion binding Human UniProtKB:D5LMF5 ZNF10 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P21506 Zinc finger protein 10 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF100 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8IYN0 Zinc finger protein 100 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF101 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8IZC7 Zinc finger protein 101 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF107 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9UII5 Zinc finger protein 107 protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0005575=ND, GO:0003677=IEA, GO:0006351=IEA} biological_process, regulation of transcription, DNA-dependent, transcription, DNA-dependent cellular_component, nucleus DNA binding, molecular_function, zinc ion binding Human ZNF117 UniProtKB UniProtKB {GO:0006355=GO_REF:0000029, GO:0003700=PMID:2023909, GO:0008270=PMID:2505992, GO:0005634=GO_REF:0000029, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q03924 Zinc finger protein 117 protein 20021104 {GO:0006355=NAS, GO:0003700=NAS, GO:0008270=NAS, GO:0005634=NAS, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZNF12 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0005634=PMID:16806083, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0045892=PMID:16806083, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P17014 Zinc finger protein 12 protein 20101101 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0003676=IEA, GO:0045892=IDA, GO:0003677=IEA, GO:0006351=IEA} negative regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human ZNF121 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P58317 Zinc finger protein 121 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF124 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q15973 Zinc finger protein 124 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF131 GOC UniProtKB {GO:0006355=PMID:7557990, GO:0003700=PMID:7557990, GO:0006366=GO_REF:0000033, GO:0006357=GO_REF:0000033, GO:0000981=GO_REF:0000033, GO:0005634=PMID:7557990, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037} P52739 Zinc finger protein 131 protein 20130413 {GO:0006355=NAS, GO:0003700=NAS, GO:0006366=IBA, GO:0006357=IBA, GO:0000981=IBA, GO:0005634=NAS, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA} regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity, zinc ion binding Human PANTHER:PTN000003381 ZNF133 InterPro UniProtKB {GO:0005515=PMID:20195357, GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0003700=PMID:7557990, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q5JXW1 Zinc finger protein 133 protein 20130413 {GO:0005515=IPI, GO:0005622=IEA, GO:0006355=IEA, GO:0003700=TAS, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, protein binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human InterPro:IPR001909 ZNF135 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0003700=PMID:7557990, GO:0022604=PMID:21834987, GO:0007010=PMID:21834987, GO:0005634=PMID:7557990, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8N9M3 Zinc finger protein 135 (Clone pHZ-17), isoform CRA_a protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0003700=NAS, GO:0022604=IMP, GO:0007010=IMP, GO:0005634=NAS, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} cytoskeleton organization, regulation of cell morphogenesis, regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human InterPro:IPR007087 ZNF136 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0006366=PMID:7649249, GO:0003714=PMID:7649249, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0000122=PMID:7649249, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037} P52737 Zinc finger protein 136 protein 20130415 {GO:0005515=IPI, GO:0006366=TAS, GO:0003714=TAS, GO:0005634=IEA, GO:0008270=IEA, GO:0000122=TAS, GO:0003676=IEA, GO:0003677=IEA} negative regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter nucleus DNA binding, nucleic acid binding, protein binding, transcription corepressor activity, zinc ion binding Human UniProtKB:Q99750 ZNF138 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=PMID:7557990, GO:0003700=PMID:7557990, GO:0005634=PMID:7557990, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P52744 Zinc finger protein 138 protein 20010927 {GO:0005622=IEA, GO:0006355=NAS, GO:0003700=NAS, GO:0005634=NAS, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZNF14 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P17017 Zinc finger protein 14 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF140 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0003700=PMID:7557990, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q05CP6 cDNA FLJ58377, highly similar to Zinc finger protein 140 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0003700=TAS, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human InterPro:IPR007087 ZNF141 PINC UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0006366=PMID:8268908, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0009653=PMID:8268908, GO:0003677=GO_REF:0000037} Q15928 Zinc finger protein 141 protein 20031119 {GO:0005622=IEA, GO:0006355=IEA, GO:0006366=TAS, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0009653=TAS, GO:0003677=IEA} anatomical structure morphogenesis, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human ZNF142 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P52746 Zinc finger protein 142 protein 20101022 {GO:0008150=ND, GO:0003674=ND, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0005575=ND, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} biological_process, regulation of transcription, DNA-dependent, transcription, DNA-dependent cellular_component, nucleus DNA binding, molecular_function, nucleic acid binding, zinc ion binding Human ZNF143 Reactome UniProtKB {GO:0005515=PMID:17938208, GO:0010467=Reactome:REACT_71, GO:0006357=PMID:9566884, GO:0006366=PMID:9009278, GO:0006359=PMID:9566884, GO:0005654=Reactome:REACT_1607, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0006383=Reactome:REACT_1371, GO:0003677=GO_REF:0000019} P52747 Zinc finger protein 143 protein 20130213 {GO:0005515=IPI, GO:0010467=TAS, GO:0006357=TAS, GO:0006366=TAS, GO:0006359=TAS, GO:0005654=TAS, GO:0008270=IEA, GO:0003676=IEA, GO:0006383=TAS, GO:0003677=IEA} gene expression, regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase III promoter, transcription from RNA polymerase II promoter, transcription from RNA polymerase III promoter nucleoplasm DNA binding, nucleic acid binding, protein binding, zinc ion binding Human ZNF146 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0006355=PMID:8107129, GO:0005730=GO_REF:0000052, GO:0005634=PMID:8665923, GO:0008270=GO_REF:0000002, GO:0008201=PMID:8665923, GO:0003677=GO_REF:0000037} Q15072 Zinc finger protein OZF protein 20101115 {GO:0005737=IDA, GO:0006355=TAS, GO:0005730=IDA, GO:0005634=TAS, GO:0008270=IEA, GO:0008201=TAS, GO:0003677=IEA} regulation of transcription, DNA-dependent cytoplasm, nucleolus, nucleus DNA binding, heparin binding, zinc ion binding Human ZNF148 HPA UniProtKB {GO:0005515=PMID:12771217, GO:0000976=GO_REF:0000019, GO:0005794=GO_REF:0000052, GO:0003700=GO_REF:0000019, GO:0006366=PMID:9685330, GO:0007276=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000122=GO_REF:0000019, GO:0003676=GO_REF:0000002, GO:0043565=PMID:12771217, GO:0006968=PMID:8355710, GO:0003690=GO_REF:0000019, GO:0006461=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0010629=PMID:12771217, GO:0008270=GO_REF:0000002, GO:0045892=PMID:12771217} Q9UQR1 Zinc finger protein 148 protein 20101115 {GO:0005515=IPI, GO:0000976=IEA, GO:0005794=IDA, GO:0003700=IEA, GO:0006366=TAS, GO:0007276=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0000122=IEA, GO:0003676=IEA, GO:0043565=IDA, GO:0006968=TAS, GO:0003690=IEA, GO:0006461=IEA, GO:0045944=IEA, GO:0010629=IDA, GO:0008270=IEA, GO:0045892=IDA} cellular defense response, gamete generation, negative regulation of gene expression, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, positive regulation of transcription from RNA polymerase II promoter, protein complex assembly, transcription from RNA polymerase II promoter Golgi apparatus, nucleolus, nucleus double-stranded DNA binding, nucleic acid binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding, zinc ion binding Human ZNF155 PINC UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0003700=PMID:7557990, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q12901 Zinc finger protein 155 protein 20030904 {GO:0005622=IEA, GO:0006355=IEA, GO:0003700=TAS, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZNF16 IntAct UniProtKB {GO:0005515=PMID:21874239, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P17020 Zinc finger protein 16 protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, protein binding, zinc ion binding Human UniProtKB:Q0VD86 ZNF160 UniProtKB UniProtKB {GO:0030097=PMID:11410164, GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000029, GO:0005634=GO_REF:0000029, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9HCG1 Zinc finger protein 160 protein 20021104 {GO:0030097=NAS, GO:0005622=IEA, GO:0006355=NAS, GO:0005634=NAS, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} hemopoiesis, regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human ZNF165 IntAct UniProtKB {GO:0005515=PMID:16189514, GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000029, GO:0016032=GO_REF:0000002, GO:0005634=GO_REF:0000029, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P49910 Zinc finger protein 165 protein 20130415 {GO:0005515=IPI, GO:0006355=NAS, GO:0003700=NAS, GO:0016032=IEA, GO:0005634=NAS, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent, viral reproduction nucleus DNA binding, protein binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB:Q01844 ZNF17 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P17021 Zinc finger protein 17 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF174 GOC UniProtKB {GO:0003700=PMID:7673192, GO:0044212=PMID:7673192, GO:0006366=GO_REF:0000033, GO:0000981=GO_REF:0000033, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0000122=PMID:7673192, GO:0015629=GO_REF:0000052, GO:0042803=PMID:15629724, GO:0005737=GO_REF:0000052, GO:0016032=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0045892=PMID:7673192} Q15697 Zinc finger protein 174 protein 20130413 {GO:0003700=IDA, GO:0044212=IDA, GO:0006366=IBA, GO:0000981=IBA, GO:0005730=IDA, GO:0005634=IDA, GO:0000122=IDA, GO:0015629=IDA, GO:0042803=IPI, GO:0005737=IDA, GO:0016032=IEA, GO:0008270=IEA, GO:0045892=IDA} negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter, viral reproduction actin cytoskeleton, cytoplasm, nucleolus, nucleus protein homodimerization activity, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding, zinc ion binding Human PANTHER:PTN000003381 ZNF175 HPA UniProtKB {GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0051607=GO_REF:0000037, GO:0006355=GO_REF:0000002, GO:0003700=PMID:8838321, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0045111=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9Y473 Zinc finger protein 175 protein 20101115 {GO:0005622=IEA, GO:0005737=IDA, GO:0051607=IEA, GO:0006355=IEA, GO:0003700=TAS, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0045111=IDA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} defense response to virus, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, intermediate filament cytoskeleton, intracellular, nucleolus, nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZNF177 PINC UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0000122=PMID:8661005, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q13360 Zinc finger protein 177 protein 20030904 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0000122=TAS, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} negative regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human ZNF18 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0006366=GO_REF:0000033, GO:0006357=GO_REF:0000033, GO:0000981=GO_REF:0000033, GO:0016032=GO_REF:0000002, GO:0005634=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037} Q96LU8 cDNA FLJ25054 fis, clone CBL04360 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0003700=IEA, GO:0006366=IBA, GO:0006357=IBA, GO:0000981=IBA, GO:0016032=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA} regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter, viral reproduction intracellular, nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity, zinc ion binding Human InterPro:IPR008916 ZNF181 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q2M3W8 Zinc finger protein 181 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF184 UniProtKB UniProtKB {GO:0006355=GO_REF:0000029, GO:0005634=GO_REF:0000029, GO:0008270=PMID:9073517, GO:0003677=GO_REF:0000029, GO:0006351=GO_REF:0000037} Q99676 Zinc finger protein 184 protein 20021104 {GO:0006355=NAS, GO:0005634=NAS, GO:0008270=NAS, GO:0003677=NAS, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human ZNF185 UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0005856=GO_REF:0000039, GO:0005925=GO_REF:0000039} O15231 Zinc finger protein 185 protein 20130413 {GO:0005737=IEA, GO:0008270=IEA, GO:0005856=IEA, GO:0005925=IEA} cytoplasm, cytoskeleton, focal adhesion zinc ion binding Human UniProtKB-SubCell:SL-0118 ZNF189 PINC UniProtKB {GO:0003700=PMID:9653648, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0000122=PMID:9653648, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O75820 Zinc finger protein 189 protein 20030904 {GO:0003700=TAS, GO:0005634=IEA, GO:0008270=IEA, GO:0000122=TAS, GO:0003677=IEA, GO:0006351=IEA} negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZNF195 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000029, GO:0005634=GO_REF:0000029, GO:0008270=PMID:9344677, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000029, GO:0006351=GO_REF:0000037} O14628 Zinc finger protein 195 protein 20021104 {GO:0005622=IEA, GO:0006355=NAS, GO:0005634=NAS, GO:0008270=NAS, GO:0003676=IEA, GO:0003677=NAS, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human ZNF197 UniProtKB UniProtKB {GO:0003700=GO_REF:0000002, GO:0016032=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O14709 Zinc finger protein 197 protein 20130413 {GO:0003700=IEA, GO:0016032=IEA, GO:0008270=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} transcription, DNA-dependent, viral reproduction nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF2 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=PMID:1945843, GO:0005634=GO_REF:0000029, GO:0008270=PMID:1945843, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9BSG1 Zinc finger protein 2 protein 20070906 {GO:0005622=IEA, GO:0006355=NAS, GO:0005634=NAS, GO:0008270=NAS, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human ZNF20 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P17024 Zinc finger protein 20 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF200 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000029, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} P98182 Zinc finger protein 200 protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0006355=IEA, GO:0005634=NAS, GO:0008270=IEA, GO:0003676=IEA, GO:0006351=IEA} biological_process, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus molecular_function, nucleic acid binding, zinc ion binding Human ZNF202 PINC UniProtKB {GO:0006629=PMID:10748193, GO:0003700=PMID:9790754, GO:0006366=PMID:10748193, GO:0000981=GO_REF:0000033, GO:0016032=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000033, GO:0000122=PMID:10748193, GO:0003677=GO_REF:0000037} O95125 Zinc finger protein 202 protein 20030904 {GO:0006629=TAS, GO:0003700=TAS, GO:0006366=TAS, GO:0000981=IBA, GO:0016032=IEA, GO:0008270=IEA, GO:0005634=IBA, GO:0000122=TAS, GO:0003677=IEA} lipid metabolic process, negative regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter, viral reproduction nucleus DNA binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZNF205 BHF-UCL UniProtKB {GO:0005515=PMID:16713569, GO:0005622=GO_REF:0000002, GO:0006355=PMID:9787081, GO:1901030=PMID:22306510, GO:0010729=PMID:22306510, GO:0005634=GO_REF:0000029, GO:0008270=PMID:9787081, GO:0000122=PMID:22306510, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000029, GO:0006351=GO_REF:0000037} O95201 Zinc finger protein 205 protein 20121109 {GO:0005515=IPI, GO:0005622=IEA, GO:0006355=NAS, GO:1901030=IMP, GO:0010729=IMP, GO:0005634=NAS, GO:0008270=NAS, GO:0000122=IMP, GO:0003676=IEA, GO:0003677=NAS, GO:0006351=IEA} negative regulation of transcription from RNA polymerase II promoter, positive regulation of hydrogen peroxide biosynthetic process, positive regulation of mitochondrial outer membrane permeabilization, regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, protein binding, zinc ion binding Human ZNF207 HPA UniProtKB {GO:0006355=PMID:9799612, GO:0003700=PMID:9799612, GO:0005730=GO_REF:0000052, GO:0008270=PMID:9799612, GO:0005634=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0008201=GO_REF:0000019} O43670 Zinc finger protein 207 protein 20090616 {GO:0006355=NAS, GO:0003700=NAS, GO:0005730=IDA, GO:0008270=NAS, GO:0005634=IDA, GO:0003677=IEA, GO:0008201=IEA} regulation of transcription, DNA-dependent nucleolus, nucleus DNA binding, heparin binding, sequence-specific DNA binding transcription factor activity, zinc ion binding NOT Human ZNF208 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000029, GO:0008270=PMID:9724325, GO:0005634=GO_REF:0000029, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000029, GO:0006351=GO_REF:0000037} O43345 Zinc finger protein 208 protein 20010905 {GO:0005622=IEA, GO:0006355=NAS, GO:0008270=NAS, GO:0005634=NAS, GO:0003676=IEA, GO:0003677=NAS, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human ZNF211 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q13398 Zinc finger protein 211 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF212 IntAct UniProtKB {GO:0005515=PMID:18255255, GO:0005622=GO_REF:0000002, GO:0006355=PMID:7633419, GO:0008270=PMID:7633419, GO:0005634=GO_REF:0000029, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000029, GO:0006351=GO_REF:0000037, GO:0042802=PMID:18255255} Q9UDV6 Zinc finger protein 212 protein 20130415 {GO:0005515=IPI, GO:0005622=IEA, GO:0006355=NAS, GO:0008270=NAS, GO:0005634=NAS, GO:0003676=IEA, GO:0003677=NAS, GO:0006351=IEA, GO:0042802=IPI} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, identical protein binding, nucleic acid binding, protein binding, zinc ion binding Human UniProtKB:Q9UDV6 ZNF213 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0003700=GO_REF:0000002, GO:0016032=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O14771 Zinc finger protein 213 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0003700=IEA, GO:0016032=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent, viral reproduction intracellular, nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF215 GOC UniProtKB {GO:0006355=GO_REF:0000029, GO:0003700=PMID:10762538, GO:0006366=GO_REF:0000033, GO:0006357=GO_REF:0000033, GO:0000981=GO_REF:0000033, GO:0016032=GO_REF:0000002, GO:0008270=GO_REF:0000029, GO:0005634=GO_REF:0000029, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037} Q9UL58 Zinc finger protein 215 protein 20130413 {GO:0006355=NAS, GO:0003700=NAS, GO:0006366=IBA, GO:0006357=IBA, GO:0000981=IBA, GO:0016032=IEA, GO:0008270=NAS, GO:0005634=NAS, GO:0003676=IEA, GO:0003677=IEA} regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter, viral reproduction nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity, zinc ion binding Human PANTHER:PTN000003381 ZNF217 PINC UniProtKB {GO:0005515=PMID:16940172, GO:0006355=PMID:18625718, GO:0003700=PMID:9671742, GO:0000118=PMID:18625718, GO:0044212=PMID:18625718, GO:0005654=PMID:18625718, GO:0008270=GO_REF:0000002, GO:0045892=PMID:16940172, GO:0006351=GO_REF:0000037} O75362 Zinc finger protein 217 protein 20030904 {GO:0005515=IPI, GO:0006355=IDA, GO:0003700=TAS, GO:0000118=IDA, GO:0044212=IDA, GO:0005654=IDA, GO:0008270=IEA, GO:0045892=IDA, GO:0006351=IEA} negative regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent histone deacetylase complex, nucleoplasm protein binding, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding, zinc ion binding Human ZNF219 UniProtKB UniProtKB {GO:0005515=PMID:19549071, GO:0006355=PMID:19549071, GO:0003700=PMID:19549071, GO:0005634=PMID:14621294, GO:0003676=GO_REF:0000002, GO:0004969=GO_REF:0000002, GO:0007204=GO_REF:0000002, GO:0003677=PMID:14621294, GO:0006351=PMID:14621294, GO:0001505=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000002, GO:0030814=GO_REF:0000002, GO:0045892=PMID:14621294} Q9P2Y4 Zinc finger protein 219 protein 20090630 {GO:0005515=IPI, GO:0006355=IMP, GO:0003700=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0004969=IEA, GO:0007204=IEA, GO:0003677=IDA, GO:0006351=IDA, GO:0001505=IEA, GO:0008270=IEA, GO:0016021=IEA, GO:0030814=IEA, GO:0045892=IDA} elevation of cytosolic calcium ion concentration, negative regulation of transcription, DNA-dependent, regulation of cAMP metabolic process, regulation of neurotransmitter levels, regulation of transcription, DNA-dependent, transcription, DNA-dependent integral to membrane, nucleus DNA binding, histamine receptor activity, nucleic acid binding, protein binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZNF22 HPA UniProtKB {GO:0006355=PMID:14630903, GO:0005886=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0042476=PMID:14630903, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000024, GO:0006351=GO_REF:0000037} P17026 Zinc finger protein 22 protein 20101115 {GO:0006355=NAS, GO:0005886=IDA, GO:0005730=IDA, GO:0042476=NAS, GO:0005634=IDA, GO:0008270=IEA, GO:0003677=ISS, GO:0006351=IEA} odontogenesis, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus, nucleus, plasma membrane DNA binding, zinc ion binding Human ZNF221 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9UK13 Zinc finger protein 221 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF222 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9UK12 Zinc finger protein 222 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF223 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0008150=GO_REF:0000015, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000029, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=PMID:10449920, GO:0006351=GO_REF:0000037} Q9UK11 Zinc finger protein 223 protein 20061026 {GO:0005622=IEA, GO:0008150=ND, GO:0006355=IEA, GO:0005634=NAS, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=NAS, GO:0006351=IEA} biological_process, regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human ZNF224 UniProtKB UniProtKB {GO:0005515=PMID:20587513, GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0017053=PMID:20587513, GO:0005634=PMID:20587513, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0045892=PMID:20587513, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9NZL3 Zinc finger protein 224 protein 20101214 {GO:0005515=IPI, GO:0005622=IEA, GO:0006355=IEA, GO:0017053=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003676=IEA, GO:0045892=IDA, GO:0003677=IEA, GO:0006351=IEA} negative regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus, transcriptional repressor complex DNA binding, nucleic acid binding, protein binding, zinc ion binding Human ZNF226 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9NYT6 Zinc finger protein 226 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF227 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q86WZ6 Zinc finger protein 227 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF229 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9UJW7 Zinc finger protein 229 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF23 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P17027 Zinc finger protein 23 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF230 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9UIE0 Zinc finger protein 230 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF232 UniProtKB UniProtKB {GO:0003700=GO_REF:0000002, GO:0016032=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9UNY5 Zinc finger protein 232 protein 20130413 {GO:0003700=IEA, GO:0016032=IEA, GO:0008270=IEA, GO:0005634=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} transcription, DNA-dependent, viral reproduction nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF233 HPA UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9NS42 Hypothetical zinc finger-like protein protein 20100326 {GO:0005622=IEA, GO:0006355=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleolus, nucleus DNA binding, nucleic acid binding, zinc ion binding NOT Human ZNF234 HPA UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q14588 Zinc finger protein 234 protein 20080818 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human ZNF235 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q14590 Zinc finger protein 235 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF236 UniProtKB UniProtKB {GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000029, GO:0005634=GO_REF:0000029, GO:0008270=GO_REF:0000002, GO:0071333=PMID:9299475, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9UL36 Zinc finger protein 236 protein 20101022 {GO:0006355=NAS, GO:0003700=NAS, GO:0005634=NAS, GO:0008270=IEA, GO:0071333=IEP, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} cellular response to glucose stimulus, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZNF239 PINC UniProtKB {GO:0006355=GO_REF:0000037, GO:0003723=PMID:9121460, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q16600 Zinc finger protein 239 protein 20030904 {GO:0006355=IEA, GO:0003723=TAS, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, RNA binding, zinc ion binding Human ZNF24 HPA UniProtKB {GO:0005515=PMID:19060904, GO:0043565=GO_REF:0000024, GO:0003700=GO_REF:0000002, GO:0042552=GO_REF:0000024, GO:0016032=GO_REF:0000002, GO:0008270=PMID:10585455, GO:0005634=GO_REF:0000052, GO:0003677=PMID:2288909, GO:0045892=PMID:10585455, GO:0006351=GO_REF:0000037} P17028 Zinc finger protein 24 protein 20100326 {GO:0005515=IPI, GO:0043565=ISS, GO:0003700=IEA, GO:0042552=ISS, GO:0016032=IEA, GO:0008270=NAS, GO:0005634=IDA, GO:0003677=TAS, GO:0045892=IDA, GO:0006351=IEA} myelination, negative regulation of transcription, DNA-dependent, transcription, DNA-dependent, viral reproduction nucleus DNA binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZNF248 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8NDW4 Zinc finger protein 248 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF25 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P17030 Zinc finger protein 25 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF250 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q3B7J8 ZNF250 protein protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human InterPro:IPR001909 ZNF251 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9BRH9 Zinc finger protein 251 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF253 UniProtKB UniProtKB {GO:0006355=PMID:10585455, GO:0005634=GO_REF:0000029, GO:0008270=PMID:10585455, GO:0003676=GO_REF:0000002, GO:0045892=PMID:10585455, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O75346 Zinc finger protein 253 protein 20021104 {GO:0006355=NAS, GO:0005634=NAS, GO:0008270=NAS, GO:0003676=IEA, GO:0045892=NAS, GO:0003677=IEA, GO:0006351=IEA} negative regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human ZNF254 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0000122=PMID:10585455, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q7Z2R1 Zinc finger protein 254 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0000122=TAS, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} negative regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human InterPro:IPR001909 ZNF256 PINC UniProtKB {GO:0005515=PMID:18060868, GO:0003700=PMID:10585455, GO:0007275=PMID:10585455, GO:0005634=PMID:18060868, GO:0008270=GO_REF:0000002, GO:0045892=PMID:18060868, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9Y2P7 Zinc finger protein 256 protein 20030904 {GO:0005515=IPI, GO:0003700=TAS, GO:0007275=TAS, GO:0005634=IDA, GO:0008270=IEA, GO:0045892=IDA, GO:0003677=IEA, GO:0006351=IEA} multicellular organismal development, negative regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, protein binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZNF257 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=PMID:10585455, GO:0005634=GO_REF:0000029, GO:0008270=PMID:10585455, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000029, GO:0006351=GO_REF:0000037} Q9Y2Q1 Zinc finger protein 257 protein 20021104 {GO:0005622=IEA, GO:0006355=NAS, GO:0005634=NAS, GO:0008270=NAS, GO:0003676=IEA, GO:0003677=NAS, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human ZNF259 PINC UniProtKB {GO:0007165=PMID:8650580, GO:0005737=GO_REF:0000039, GO:0008283=PMID:9763455, GO:0005730=GO_REF:0000039, GO:0005634=PMID:8650580, GO:0008270=GO_REF:0000019} O75312 Zinc finger protein ZPR1 protein 20030904 {GO:0007165=TAS, GO:0005737=IEA, GO:0008283=TAS, GO:0005730=IEA, GO:0005634=TAS, GO:0008270=IEA} cell proliferation, signal transduction cytoplasm, nucleolus, nucleus zinc ion binding Human ZNF260 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0007275=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q3ZCT1 Zinc finger protein 260 protein 20111111 {GO:0005737=IDA, GO:0006355=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0007275=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} multicellular organismal development, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleolus, nucleus DNA binding, zinc ion binding Human ZNF263 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0006355=PMID:9256059, GO:0003700=GO_REF:0000002, GO:0015630=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0016032=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0045892=GO_REF:0000019, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037} O14978 Zinc finger protein 263 protein 20101115 {GO:0005737=IDA, GO:0006355=TAS, GO:0003700=IEA, GO:0015630=IDA, GO:0005730=IDA, GO:0016032=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0003676=IEA, GO:0045892=IEA, GO:0003677=IEA, GO:0006351=IEA} negative regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent, viral reproduction cytoplasm, microtubule cytoskeleton, nucleolus, nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZNF264 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O43296 Zinc finger protein 264 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF266 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q14584 Zinc finger protein 266 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF267 PINC UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0007275=PMID:7865130, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q14586 Zinc finger protein 267 protein 20030904 {GO:0005622=IEA, GO:0006355=IEA, GO:0007275=TAS, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} multicellular organismal development, regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human ZNF273 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q14593 Zinc finger protein 273 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF274 HPA UniProtKB {GO:0005515=PMID:21170338, GO:0005813=GO_REF:0000052, GO:0006355=PMID:10520746, GO:0003700=GO_REF:0000002, GO:0003714=PMID:10777669, GO:0005730=GO_REF:0000039, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0005622=GO_REF:0000002, GO:0043565=PMID:21170338, GO:0005737=GO_REF:0000039, GO:0016032=GO_REF:0000002, GO:0008270=GO_REF:0000002} Q96GC6 Neurotrophin receptor-interacting factor homolog protein 20101115 {GO:0005515=IPI, GO:0005813=IDA, GO:0006355=TAS, GO:0003700=IEA, GO:0003714=TAS, GO:0005730=IEA, GO:0005634=IDA, GO:0003676=IEA, GO:0006351=IEA, GO:0005622=IEA, GO:0043565=IDA, GO:0005737=IEA, GO:0016032=IEA, GO:0008270=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent, viral reproduction centrosome, cytoplasm, intracellular, nucleolus, nucleus nucleic acid binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity, zinc ion binding Human ZNF276 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8N554 Zinc finger protein 276 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF277 UniProtKB UniProtKB {GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000029, GO:0005634=GO_REF:0000029, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9NRM2 Zinc finger protein 277 protein 20021104 {GO:0006355=NAS, GO:0003700=NAS, GO:0005634=NAS, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZNF28 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P17035 Zinc finger protein 28 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF280B UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q86YH2 Zinc finger protein 280B protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF280C InterPro UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9UJJ2 Zinc finger protein 280C protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human InterPro:IPR007087 ZNF280D UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6N043 Zinc finger protein 280D protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF281 HPA UniProtKB {GO:0005515=PMID:17314511, GO:0010172=GO_REF:0000024, GO:0003700=PMID:10448078, GO:0044212=PMID:10448078, GO:0003714=GO_REF:0000024, GO:0005730=GO_REF:0000052, GO:0001047=GO_REF:0000024, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0048863=GO_REF:0000024, GO:0043565=PMID:12771217, GO:0010629=PMID:10448078, GO:0008270=GO_REF:0000002, GO:0045893=PMID:10405178, GO:0045892=PMID:12771217} Q9Y2X9 Zinc finger protein 281 protein 20120912 {GO:0005515=IPI, GO:0010172=ISS, GO:0003700=IDA, GO:0044212=IDA, GO:0003714=ISS, GO:0005730=IDA, GO:0001047=ISS, GO:0005634=IDA, GO:0003676=IEA, GO:0006351=IEA, GO:0048863=ISS, GO:0043565=IDA, GO:0010629=IMP, GO:0008270=IEA, GO:0045893=IDA, GO:0045892=IDA} embryonic body morphogenesis, negative regulation of gene expression, negative regulation of transcription, DNA-dependent, positive regulation of transcription, DNA-dependent, stem cell differentiation, transcription, DNA-dependent nucleolus, nucleus core promoter binding, nucleic acid binding, protein binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity, transcription regulatory region DNA binding, zinc ion binding NOT Human ZNF282 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=PMID:9396811, GO:0008270=PMID:9396811, GO:0005634=GO_REF:0000029, GO:0003676=GO_REF:0000002, GO:0045892=PMID:9396811, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9UDV7 Zinc finger protein 282 protein 20010905 {GO:0005622=IEA, GO:0006355=TAS, GO:0008270=NAS, GO:0005634=NAS, GO:0003676=IEA, GO:0045892=TAS, GO:0003677=IEA, GO:0006351=IEA} negative regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human ZNF284 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q2VY69 Zinc finger protein 284 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF286B UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P0CG31 Putative zinc finger protein 286B protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF287 UniProtKB UniProtKB {GO:0042035=GO_REF:0000019, GO:0003700=GO_REF:0000002, GO:0006366=GO_REF:0000033, GO:0006357=GO_REF:0000033, GO:0014003=GO_REF:0000033, GO:0000981=GO_REF:0000033, GO:0016032=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0045893=GO_REF:0000019, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9HBT7 Zinc finger protein 287 protein 20130413 {GO:0042035=IEA, GO:0003700=IEA, GO:0006366=IBA, GO:0006357=IBA, GO:0014003=IBA, GO:0000981=IBA, GO:0016032=IEA, GO:0008270=IEA, GO:0005634=IEA, GO:0045893=IEA, GO:0003677=IEA, GO:0006351=IEA} oligodendrocyte development, positive regulation of transcription, DNA-dependent, regulation of cytokine biosynthetic process, regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription, DNA-dependent, viral reproduction nucleus DNA binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF292 UniProtKB UniProtKB {GO:0001077=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000019} O60281 Zinc finger protein 292 protein 20130413 {GO:0001077=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA} nucleus DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF3 HPA UniProtKB {GO:0005515=PMID:18255255, GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000029, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0007275=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0003677=PMID:2288909, GO:0006351=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0042802=PMID:18255255, GO:0005622=GO_REF:0000002, GO:0045321=PMID:2288909, GO:0008270=PMID:2288909} P17036 Zinc finger protein 3 protein 20080205 {GO:0005515=IPI, GO:0006355=NAS, GO:0003700=NAS, GO:0005730=IDA, GO:0005634=IDA, GO:0007275=IEA, GO:0003676=IEA, GO:0003677=NAS, GO:0006351=IEA, GO:0030154=IEA, GO:0042802=IPI, GO:0005622=IEA, GO:0045321=NAS, GO:0008270=NAS} cell differentiation, leukocyte activation, multicellular organismal development, regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleolus, nucleus DNA binding, identical protein binding, nucleic acid binding, protein binding, sequence-specific DNA binding transcription factor activity, zinc ion binding NOT Human ZNF300 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96RE9 Zinc finger protein 300 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF302 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9NR11 Zinc finger protein 302 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF311 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q5JNZ3 Zinc finger protein 311 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF317 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96PQ6 Zinc finger protein 317 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF318 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0007126=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q5VUA4 Zinc finger protein 318 protein 20101115 {GO:0005737=IDA, GO:0006355=IEA, GO:0007126=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003676=IEA, GO:0006351=IEA} meiosis, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleolus, nucleus nucleic acid binding, zinc ion binding Human ZNF319 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9P2F9 Zinc finger protein 319 protein 20130413 {GO:0006355=IEA, GO:0008270=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF32 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P17041 Zinc finger protein 32 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF320 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} M0R2Z6 Zinc finger protein 320 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human InterPro:IPR001909 ZNF322 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6U7Q0 Zinc finger protein 322 protein 20130413 {GO:0005737=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0086 ZNF324 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O75467 Zinc finger protein 324A protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF324B UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6AW86 Zinc finger protein 324B protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF326 UniProtKB UniProtKB {GO:0006397=GO_REF:0000037, GO:0044609=PMID:22446626, GO:0008380=PMID:22446626, GO:0005515=PMID:22446626, GO:0000993=PMID:22446626, GO:0005634=GO_REF:0000002, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0016363=GO_REF:0000039, GO:0032784=PMID:22446626, GO:0008270=GO_REF:0000019, GO:0005681=PMID:22446626, GO:0045893=GO_REF:0000019} Q5BKZ1 DBIRD complex subunit ZNF326 protein 20120430 {GO:0006397=IEA, GO:0044609=IDA, GO:0008380=IMP, GO:0005515=IPI, GO:0000993=IDA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0016363=IEA, GO:0032784=IMP, GO:0008270=IEA, GO:0005681=IDA, GO:0045893=IEA} RNA splicing, mRNA processing, positive regulation of transcription, DNA-dependent, regulation of DNA-dependent transcription, elongation, transcription, DNA-dependent DBIRD complex, nuclear matrix, nucleus, spliceosomal complex DNA binding, RNA polymerase II core binding, protein binding, zinc ion binding Human UniProtKB:Q8N163 ZNF329 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q86UD4 Zinc finger protein 329 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF330 UniProtKB UniProtKB {GO:0008150=GO_REF:0000015, GO:0005730=PMID:10593942, GO:0030496=PMID:10593942, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000002, GO:0046872=PMID:10593942, GO:0000775=PMID:10593942} Q9Y3S2 Zinc finger protein 330 protein 20040823 {GO:0008150=ND, GO:0005730=IDA, GO:0030496=IDA, GO:0008270=IEA, GO:0005634=IEA, GO:0046872=NAS, GO:0000775=IDA} biological_process chromosome, centromeric region, midbody, nucleolus, nucleus metal ion binding, zinc ion binding Human ZNF331 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000029, GO:0005634=GO_REF:0000029, GO:0008270=PMID:10502321, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000029, GO:0006351=GO_REF:0000037} Q9NQX6 Zinc finger protein 331 protein 20021106 {GO:0005622=IEA, GO:0006355=NAS, GO:0005634=NAS, GO:0008270=NAS, GO:0003676=IEA, GO:0003677=NAS, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human ZNF334 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9HCZ1 Zinc finger protein 334 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF335 UniProtKB UniProtKB {GO:0005515=PMID:18180299, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9H4Z2 Zinc finger protein 335 protein 20120712 {GO:0005515=IPI, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, protein binding, zinc ion binding Human UniProtKB:Q9ULM6 ZNF337 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9Y3M9 Zinc finger protein 337 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF33A InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0003700=PMID:8464732, GO:0005634=PMID:8464732, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9H5I4 Zinc finger protein 33A protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0003700=NAS, GO:0005634=NAS, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human InterPro:IPR001909 ZNF33B UniProtKB UniProtKB {GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000029, GO:0005634=GO_REF:0000029, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q06732 Zinc finger protein 33B protein 20021104 {GO:0006355=NAS, GO:0003700=NAS, GO:0005634=NAS, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZNF34 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8IZ26 Zinc finger protein 34 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF341 HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9BYN7 Zinc finger protein 341 protein 20100326 {GO:0006355=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus, nucleus DNA binding, nucleic acid binding, zinc ion binding NOT Human ZNF343 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6P1L6 Zinc finger protein 343 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF346 HPA UniProtKB {GO:0005515=PMID:21903422, GO:0003725=PMID:10488071, GO:0005737=GO_REF:0000039, GO:0005730=GO_REF:0000054, GO:0006915=GO_REF:0000019, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q9UL40 Zinc finger protein 346 protein 20090616 {GO:0005515=IPI, GO:0003725=IDA, GO:0005737=IEA, GO:0005730=IDA, GO:0006915=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0003676=IEA} apoptotic process cytoplasm, nucleolus, nucleus double-stranded RNA binding, nucleic acid binding, protein binding, zinc ion binding Human ZNF347 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96SE7 Zinc finger protein 347 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF35 PINC UniProtKB {GO:0043565=PMID:8477855, GO:0006355=PMID:2108922, GO:0048471=PMID:20186958, GO:0003700=PMID:1572646, GO:0071300=PMID:20186958, GO:0005623=GO_REF:0000024, GO:0005634=PMID:20186958, GO:0008270=GO_REF:0000002, GO:0007283=PMID:20186958, GO:0003676=GO_REF:0000002, GO:0003677=PMID:2108922, GO:0006351=GO_REF:0000037} P13682 Zinc finger protein 35 protein 20030904 {GO:0043565=IDA, GO:0006355=TAS, GO:0048471=IDA, GO:0003700=IDA, GO:0071300=ISS, GO:0005623=ISS, GO:0005634=IDA, GO:0008270=IEA, GO:0007283=ISS, GO:0003676=IEA, GO:0003677=TAS, GO:0006351=IEA} cellular response to retinoic acid, regulation of transcription, DNA-dependent, spermatogenesis, transcription, DNA-dependent cell, nucleus, perinuclear region of cytoplasm DNA binding, nucleic acid binding, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZNF350 HPA UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=PMID:11090615, GO:0017053=PMID:11090615, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=PMID:11090615, GO:0045892=PMID:11090615, GO:0016363=GO_REF:0000039, GO:0006351=GO_REF:0000037} Q9GZX5 Zinc finger protein 350 protein 20101115 {GO:0005622=IEA, GO:0006355=IDA, GO:0017053=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IDA, GO:0045892=IDA, GO:0016363=IEA, GO:0006351=IEA} negative regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nuclear matrix, nucleolus, nucleus, transcriptional repressor complex DNA binding, nucleic acid binding, zinc ion binding NOT Human ZNF354A PINC UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0006357=PMID:9919311, GO:0007605=PMID:9919311, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O60765 Zinc finger protein 354A protein 20030904 {GO:0005622=IEA, GO:0006355=IEA, GO:0006357=TAS, GO:0007605=TAS, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, sensory perception of sound, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human ZNF354C UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q86Y25 Zinc finger protein 354C protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF358 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0019827=GO_REF:0000024, GO:0021915=GO_REF:0000024, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0035115=GO_REF:0000024, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9NW07 Zinc finger protein 358 protein 20090626 {GO:0006355=IEA, GO:0019827=ISS, GO:0021915=ISS, GO:0005634=IEA, GO:0008270=IEA, GO:0035115=ISS, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} embryonic forelimb morphogenesis, neural tube development, regulation of transcription, DNA-dependent, stem cell maintenance, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB:Q923T4 ZNF362 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q5T0B9 Zinc finger protein 362 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF365 UniProtKB UniProtKB {GO:0005737=GO_REF:0000037, GO:0005815=GO_REF:0000039} Q70YC5 Protein ZNF365 protein 20130413 {GO:0005737=IEA, GO:0005815=IEA} cytoplasm, microtubule organizing center Human UniProtKB-SubCell:SL-0048 ZNF367 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0003700=PMID:15344908, GO:0006357=PMID:15344908, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q7RTV3 Zinc finger protein 367 protein 20101115 {GO:0005737=IDA, GO:0003700=IDA, GO:0006357=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent cytoplasm, nucleolus, nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZNF382 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0045892=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q96SR6 Zinc finger protein 382 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0045892=IEA, GO:0006351=IEA} negative regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF383 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000039, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8NA42 Zinc finger protein 383 protein 20130413 {GO:0005622=IEA, GO:0005737=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0086 ZNF384 HPA UniProtKB {GO:0043565=GO_REF:0000019, GO:0017124=GO_REF:0000019, GO:0045944=GO_REF:0000019, GO:0050714=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0005925=GO_REF:0000019, GO:0006351=GO_REF:0000037, GO:0006913=GO_REF:0000019} Q8TF68 Zinc finger protein 384 protein 20080205 {GO:0043565=IEA, GO:0017124=IEA, GO:0045944=IEA, GO:0050714=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003676=IEA, GO:0005925=IEA, GO:0006351=IEA, GO:0006913=IEA} nucleocytoplasmic transport, positive regulation of protein secretion, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent focal adhesion, nucleolus, nucleus SH3 domain binding, nucleic acid binding, sequence-specific DNA binding, zinc ion binding NOT Human ZNF385A UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96PM9 Zinc finger protein 385A protein 20130413 {GO:0005737=IEA, GO:0006355=IEA, GO:0005730=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleolus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0086 ZNF394 UniProtKB UniProtKB {GO:0003700=GO_REF:0000002, GO:0016032=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q53GI3 Zinc finger protein 394 protein 20130413 {GO:0003700=IEA, GO:0016032=IEA, GO:0008270=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} transcription, DNA-dependent, viral reproduction nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF395 UniProtKB UniProtKB {GO:0006355=PMID:14625278, GO:0005737=PMID:14625278, GO:0005634=PMID:14625278, GO:0008270=GO_REF:0000002, GO:0003677=PMID:14625278, GO:0006351=GO_REF:0000037} Q9H8N7 Zinc finger protein 395 protein 20060209 {GO:0006355=IC, GO:0005737=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003677=IDA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleus DNA binding, zinc ion binding Human GO:0003677 ZNF396 UniProtKB UniProtKB {GO:0005737=GO_REF:0000039, GO:0003700=GO_REF:0000002, GO:0016032=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96N95 Zinc finger protein 396 protein 20130413 {GO:0005737=IEA, GO:0003700=IEA, GO:0016032=IEA, GO:0008270=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} transcription, DNA-dependent, viral reproduction cytoplasm, nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB-SubCell:SL-0086 ZNF397 InterPro UniProtKB {GO:0005737=GO_REF:0000039, GO:0003700=GO_REF:0000002, GO:0016032=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96K65 cDNA FLJ14478 fis, clone MAMMA1001633, moderately similar to ZINC FINGER PROTEIN 165 protein 20130413 {GO:0005737=IEA, GO:0003700=IEA, GO:0016032=IEA, GO:0008270=IEA, GO:0005634=IEA, GO:0003677=IEA, GO:0006351=IEA} transcription, DNA-dependent, viral reproduction cytoplasm, nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human InterPro:IPR008916 ZNF398 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=PMID:11779858, GO:0005634=PMID:11779858, GO:0008270=GO_REF:0000002, GO:0045893=PMID:11779858, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8TD17 Zinc finger protein 398 protein 20021017 {GO:0005622=IEA, GO:0006355=NAS, GO:0005634=NAS, GO:0008270=IEA, GO:0045893=NAS, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human ZNF407 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9C0G0 Zinc finger protein 407 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF408 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0042802=PMID:18255255} Q9H9D4 Zinc finger protein 408 protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0042802=IPI} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, identical protein binding, protein binding, zinc ion binding Human UniProtKB:Q9H9D4 ZNF41 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000029, GO:0005634=GO_REF:0000029, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000029, GO:0006351=GO_REF:0000037} P51814 Zinc finger protein 41 protein 20021106 {GO:0005622=IEA, GO:0006355=NAS, GO:0003700=NAS, GO:0005634=NAS, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=NAS, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZNF410 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q86VK4 Zinc finger protein 410 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF414 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96IQ9 Zinc finger protein 414 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF415 HPA UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005737=GO_REF:0000052, GO:0015630=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q09FC8 Zinc finger protein 415 protein 20090616 {GO:0005622=IEA, GO:0006355=IEA, GO:0005737=IDA, GO:0015630=IDA, GO:0005730=IDA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, intracellular, microtubule cytoskeleton, nucleolus DNA binding, nucleic acid binding, zinc ion binding Human ZNF417 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8TAU3 Zinc finger protein 417 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF418 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8TF45 Zinc finger protein 418 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF419 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96HQ0 Zinc finger protein 419 protein 20130413 {GO:0005622=IEA, GO:0005737=IDA, GO:0006355=IEA, GO:0005730=IDA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, intracellular, nucleolus, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF420 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96ML5 cDNA FLJ32191 fis, clone PLACE6002151, moderately similar to ZINC FINGER PROTEIN 84 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human InterPro:IPR007087 ZNF423 IntAct UniProtKB {GO:0005515=PMID:22863007, GO:0030513=GO_REF:0000024, GO:0007219=GO_REF:0000024, GO:0005634=PMID:10660046, GO:0008270=GO_REF:0000002, GO:0045893=PMID:10660046, GO:0003676=GO_REF:0000002, GO:0045892=PMID:10660046, GO:0003677=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0007399=GO_REF:0000037} Q2M1K9 Zinc finger protein 423 protein 20130415 {GO:0005515=IPI, GO:0030513=ISS, GO:0007219=ISS, GO:0005634=IDA, GO:0008270=IEA, GO:0045893=IDA, GO:0003676=IEA, GO:0045892=IDA, GO:0003677=IEA, GO:0030154=IEA, GO:0006351=IEA, GO:0007399=IEA} Notch signaling pathway, cell differentiation, negative regulation of transcription, DNA-dependent, nervous system development, positive regulation of BMP signaling pathway, positive regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, protein binding, zinc ion binding Human UniProtKB:P09874 ZNF426 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9BUY5 Zinc finger protein 426 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF428 InterPro UniProtKB {GO:0008270=GO_REF:0000002} Q96B54 Zinc finger protein 428 protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR007087 ZNF429 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q86V71 Zinc finger protein 429 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF43 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P17038 Zinc finger protein 43 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF430 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9H8G1 Zinc finger protein 430 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF431 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8TF32 Zinc finger protein 431 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF433 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8N7K0 Zinc finger protein 433 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF436 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9C0F3 Zinc finger protein 436 protein 20110516 {GO:0005737=IDA, GO:0006355=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleolus, nucleus DNA binding, nucleic acid binding, zinc ion binding Human ZNF439 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8NDP4 Zinc finger protein 439 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF44 HPA UniProtKB {GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0015630=GO_REF:0000052, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P15621 Zinc finger protein 44 protein 20101115 {GO:0005622=IEA, GO:0005737=IDA, GO:0006355=IEA, GO:0015630=IDA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, intracellular, microtubule cytoskeleton, nucleolus, nucleus DNA binding, nucleic acid binding, zinc ion binding Human ZNF440 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8IYI8 Zinc finger protein 440 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF441 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8N8Z8 Zinc finger protein 441 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF442 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9H7R0 Zinc finger protein 442 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF443 PINC UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0006950=PMID:9731181, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0006917=PMID:9731181, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9Y2A4 Zinc finger protein 443 protein 20030904 {GO:0005622=IEA, GO:0006355=IEA, GO:0006950=TAS, GO:0005634=IEA, GO:0008270=IEA, GO:0006917=TAS, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} induction of apoptosis, regulation of transcription, DNA-dependent, response to stress, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human ZNF445 UniProtKB UniProtKB {GO:0003700=GO_REF:0000002, GO:0016032=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P59923 Zinc finger protein 445 protein 20130413 {GO:0003700=IEA, GO:0016032=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} transcription, DNA-dependent, viral reproduction nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF446 GOC UniProtKB {GO:0003700=GO_REF:0000002, GO:0006366=GO_REF:0000033, GO:0006357=GO_REF:0000033, GO:0000981=GO_REF:0000033, GO:0016032=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000033, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037} Q9NWS9 Zinc finger protein 446 protein 20130413 {GO:0003700=IEA, GO:0006366=IBA, GO:0006357=IBA, GO:0000981=IBA, GO:0016032=IEA, GO:0008270=IEA, GO:0005634=IBA, GO:0003676=IEA, GO:0003677=IEA} regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter, viral reproduction nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity, zinc ion binding Human PANTHER:PTN000003381 ZNF449 UniProtKB UniProtKB {GO:0003700=GO_REF:0000002, GO:0016032=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6P9G9 Zinc finger protein 449 protein 20130413 {GO:0003700=IEA, GO:0016032=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} transcription, DNA-dependent, viral reproduction nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF45 Reactome UniProtKB {GO:0005622=GO_REF:0000002, GO:0010467=Reactome:REACT_71, GO:0006355=PMID:9570955, GO:0006367=Reactome:REACT_12627, GO:0003700=PMID:9570955, GO:0005654=Reactome:REACT_27218, GO:0007275=PMID:1559709, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037} Q02386 Zinc finger protein 45 protein 20130301 {GO:0005622=IEA, GO:0010467=TAS, GO:0006355=TAS, GO:0006367=TAS, GO:0003700=TAS, GO:0005654=TAS, GO:0007275=TAS, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA} gene expression, multicellular organismal development, regulation of transcription, DNA-dependent, transcription initiation from RNA polymerase II promoter intracellular, nucleoplasm DNA binding, nucleic acid binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZNF451 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9Y4E5 Zinc finger protein 451 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF454 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8N9F8 Zinc finger protein 454 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF460 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q14592 Zinc finger protein 460 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF461 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8TAF7 Zinc finger protein 461 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF462 UniProtKB UniProtKB {GO:0045944=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037, GO:0043392=GO_REF:0000019} Q96JM2 Zinc finger protein 462 protein 20130413 {GO:0045944=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA, GO:0043392=IEA} negative regulation of DNA binding, positive regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF467 UniProtKB UniProtKB {GO:0006355=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q7Z7K2 Zinc finger protein 467 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF468 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q5VIY5 Zinc finger protein 468 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF471 LIFEdb UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000054, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9BX82 Zinc finger protein 471 protein 20100607 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human ZNF473 Reactome UniProtKB {GO:0005515=PMID:16714279, GO:0006369=Reactome:REACT_894, GO:0010467=Reactome:REACT_71, GO:0006355=GO_REF:0000002, GO:0006398=PMID:16714279, GO:0015030=PMID:16714279, GO:0006366=Reactome:REACT_1366, GO:0008334=Reactome:REACT_1364, GO:0031124=Reactome:REACT_1768, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0005622=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0005654=Reactome:REACT_1591} Q8WTR7 Zinc finger protein 473 protein 20130109 {GO:0005515=IPI, GO:0006369=TAS, GO:0010467=TAS, GO:0006355=IEA, GO:0006398=IDA, GO:0015030=IDA, GO:0006366=TAS, GO:0008334=TAS, GO:0031124=TAS, GO:0003676=IEA, GO:0003677=IEA, GO:0005622=IEA, GO:0008270=IEA, GO:0005654=TAS} gene expression, histone mRNA 3'-end processing, histone mRNA metabolic process, mRNA 3'-end processing, regulation of transcription, DNA-dependent, termination of RNA polymerase II transcription, transcription from RNA polymerase II promoter Cajal body, intracellular, nucleoplasm DNA binding, nucleic acid binding, protein binding, zinc ion binding Human ZNF474 InterPro UniProtKB {GO:0008270=GO_REF:0000002} Q6S9Z5 Zinc finger protein 474 protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR007087 ZNF479 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96JC4 Zinc finger protein 479 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF480 HPA UniProtKB {GO:0005622=GO_REF:0000002, GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q8WV37 Zinc finger protein 480 protein 20111111 {GO:0005622=IEA, GO:0005737=IDA, GO:0006355=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003676=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, intracellular, nucleolus, nucleus nucleic acid binding, zinc ion binding Human ZNF483 UniProtKB UniProtKB {GO:0003700=GO_REF:0000002, GO:0016032=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8TF39 Zinc finger protein 483 protein 20130413 {GO:0003700=IEA, GO:0016032=IEA, GO:0008270=IEA, GO:0005634=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} transcription, DNA-dependent, viral reproduction nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF484 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q5JVG2 Zinc finger protein 484 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF485 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8NCK3 Zinc finger protein 485 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF486 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96H40 Zinc finger protein 486 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF488 GOC UniProtKB {GO:0005515=PMID:16713569, GO:0006366=GO_REF:0000033, GO:0006357=GO_REF:0000033, GO:0000981=GO_REF:0000033, GO:0048714=GO_REF:0000019, GO:0014003=GO_REF:0000033, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000033, GO:0003677=GO_REF:0000037, GO:0045892=GO_REF:0000019} Q96MN9 Zinc finger protein 488 protein 20130413 {GO:0005515=IPI, GO:0006366=IBA, GO:0006357=IBA, GO:0000981=IBA, GO:0048714=IEA, GO:0014003=IBA, GO:0008270=IEA, GO:0005634=IBA, GO:0003677=IEA, GO:0045892=IEA} negative regulation of transcription, DNA-dependent, oligodendrocyte development, positive regulation of oligodendrocyte differentiation, regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter nucleus DNA binding, protein binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, zinc ion binding Human PANTHER:PTN000003381 ZNF490 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9ULM2 Zinc finger protein 490 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF491 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8N8L2 Zinc finger protein 491 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF492 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9P255 Zinc finger protein 492 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF493 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6ZR52 Zinc finger protein 493 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF496 GOC UniProtKB {GO:0005515=PMID:16189514, GO:0016604=GO_REF:0000019, GO:0006366=GO_REF:0000033, GO:0000981=GO_REF:0000033, GO:0016032=GO_REF:0000002, GO:0005634=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0000122=GO_REF:0000019, GO:0045893=GO_REF:0000024, GO:0043621=GO_REF:0000019, GO:0003677=GO_REF:0000024} Q96IT1 Zinc finger protein 496 protein 20130413 {GO:0005515=IPI, GO:0016604=IEA, GO:0006366=IBA, GO:0000981=IBA, GO:0016032=IEA, GO:0005634=ISS, GO:0008270=IEA, GO:0000122=IEA, GO:0045893=ISS, GO:0043621=IEA, GO:0003677=ISS} negative regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter, viral reproduction nuclear body, nucleus DNA binding, protein binding, protein self-association, sequence-specific DNA binding RNA polymerase II transcription factor activity, zinc ion binding Human PANTHER:PTN000003381 ZNF501 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96CX3 Zinc finger protein 501 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF502 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8TBZ5 Zinc finger protein 502 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF503 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q96F45 Zinc finger protein 503 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF506 LIFEdb UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000054, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q5JVG8 Zinc finger protein 506 protein 20100607 {GO:0005622=IEA, GO:0006355=IEA, GO:0005730=IDA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleolus DNA binding, nucleic acid binding, zinc ion binding Human ZNF510 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9Y2H8 Zinc finger protein 510 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF512 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96ME7 Zinc finger protein 512 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF512B HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96KM6 Zinc finger protein 512B protein 20090616 {GO:0006355=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus, nucleus DNA binding, zinc ion binding NOT Human ZNF513 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0060041=PMID:20797688, GO:0044212=PMID:20797688, GO:0005634=PMID:20797688, GO:0008270=GO_REF:0000002, GO:0003677=PMID:20797688, GO:0007601=GO_REF:0000037, GO:0050896=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8N8E2 Zinc finger protein 513 protein 20101105 {GO:0006355=IEA, GO:0060041=IMP, GO:0044212=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003677=IDA, GO:0007601=IEA, GO:0050896=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, response to stimulus, retina development in camera-type eye, transcription, DNA-dependent, visual perception nucleus DNA binding, transcription regulatory region DNA binding, zinc ion binding Human ZNF516 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q92618 Zinc finger protein 516 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF518A UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6AHZ1 Zinc finger protein 518A protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF518B GOC UniProtKB {GO:0006366=GO_REF:0000033, GO:0006357=GO_REF:0000033, GO:0000981=GO_REF:0000033, GO:0005634=GO_REF:0000033, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037} Q9C0D4 Zinc finger protein 518B protein 20130413 {GO:0006366=IBA, GO:0006357=IBA, GO:0000981=IBA, GO:0005634=IBA, GO:0008270=IEA, GO:0003677=IEA} regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter nucleus DNA binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, zinc ion binding Human PANTHER:PTN000003381 ZNF519 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8TB69 Zinc finger protein 519 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF521 MGI UniProtKB {GO:0006355=GO_REF:0000037, GO:0019904=PMID:11984006, GO:0005634=PMID:12393497, GO:0007275=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96K83 Zinc finger protein 521 protein 20091021 {GO:0006355=IEA, GO:0019904=IPI, GO:0005634=IDA, GO:0007275=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0030154=IEA, GO:0006351=IEA} cell differentiation, multicellular organismal development, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, protein domain specific binding, zinc ion binding Human ZNF525 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8N782 Zinc finger protein 525 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF526 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8TF50 Zinc finger protein 526 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF528 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q3MIS6 Zinc finger protein 528 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF529 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6P280 Zinc finger protein 529 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF532 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9HCE3 Zinc finger protein 532 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF534 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q76KX8 Zinc finger protein 534 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF536 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0045665=GO_REF:0000019, GO:0048387=GO_REF:0000019, GO:0044323=GO_REF:0000019, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} O15090 Zinc finger protein 536 protein 20130413 {GO:0006355=IEA, GO:0045665=IEA, GO:0048387=IEA, GO:0044323=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0006351=IEA} negative regulation of neuron differentiation, negative regulation of retinoic acid receptor signaling pathway, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus nucleic acid binding, retinoic acid-responsive element binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF540 UniProtKB UniProtKB {GO:0005515=PMID:16815308, GO:0017148=PMID:16815308, GO:0005622=GO_REF:0000002, GO:0005737=PMID:16815308, GO:0006355=GO_REF:0000002, GO:0005634=PMID:16815308, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0045892=PMID:16815308, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8NDQ6 Zinc finger protein 540 protein 20130306 {GO:0005515=IPI, GO:0017148=IMP, GO:0005622=IEA, GO:0005737=IDA, GO:0006355=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0003676=IEA, GO:0045892=IDA, GO:0003677=IEA, GO:0006351=IEA} negative regulation of transcription, DNA-dependent, negative regulation of translation, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, intracellular, nucleus DNA binding, nucleic acid binding, protein binding, zinc ion binding Human UniProtKB:Q14764 ZNF541 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0003682=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0007275=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0007283=GO_REF:0000037, GO:0003677=GO_REF:0000002, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9H0D2 Zinc finger protein 541 protein 20130413 {GO:0006355=IEA, GO:0003682=IEA, GO:0005634=IEA, GO:0007275=IEA, GO:0008270=IEA, GO:0007283=IEA, GO:0003677=IEA, GO:0030154=IEA, GO:0006351=IEA} cell differentiation, multicellular organismal development, regulation of transcription, DNA-dependent, spermatogenesis, transcription, DNA-dependent nucleus DNA binding, chromatin binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF543 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q08ER8 Zinc finger protein 543 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF546 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q86UE3 Zinc finger protein 546 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF548 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8NEK5 Zinc finger protein 548 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF549 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6P9A3 Zinc finger protein 549 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF551 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q7Z340 Zinc finger protein 551 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF552 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9H707 Zinc finger protein 552 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF554 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q86TJ5 Zinc finger protein 554 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF555 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8NEP9 Zinc finger protein 555 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF556 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9HAH1 Zinc finger protein 556 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF557 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8N988 Zinc finger protein 557 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF558 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0008150=GO_REF:0000015, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96NG5 Zinc finger protein 558 protein 20101022 {GO:0005622=IEA, GO:0008150=ND, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0005575=ND, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} biological_process, regulation of transcription, DNA-dependent, transcription, DNA-dependent cellular_component, intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human ZNF559 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9BR84 Zinc finger protein 559 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF560 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96MR9 Zinc finger protein 560 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF561 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8N587 Zinc finger protein 561 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF562 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6V9R5 Zinc finger protein 562 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF563 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8TA94 Zinc finger protein 563 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF564 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8TBZ8 Zinc finger protein 564 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF566 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q969W8 Zinc finger protein 566 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF567 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8N184 Zinc finger protein 567 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF568 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q3ZCX4 Zinc finger protein 568 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF569 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q5MCW4 Zinc finger protein 569 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF57 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q68EA5 Zinc finger protein 57 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF570 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96NI8 Zinc finger protein 570 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF571 LIFEdb UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0019028=GO_REF:0000002, GO:0005198=GO_REF:0000002, GO:0019058=GO_REF:0000002, GO:0005634=GO_REF:0000054, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q7Z3V5 Zinc finger protein 571 protein 20100607 {GO:0005622=IEA, GO:0006355=IEA, GO:0019028=IEA, GO:0005198=IEA, GO:0019058=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent, viral infectious cycle intracellular, nucleus, viral capsid DNA binding, nucleic acid binding, structural molecule activity, zinc ion binding Human ZNF573 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q86YE8 Zinc finger protein 573 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF574 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6ZN55 Zinc finger protein 574 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF576 GOC UniProtKB {GO:0006366=GO_REF:0000033, GO:0006357=GO_REF:0000033, GO:0000981=GO_REF:0000033, GO:0005634=GO_REF:0000033, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037} Q9H609 Zinc finger protein 576 protein 20130413 {GO:0006366=IBA, GO:0006357=IBA, GO:0000981=IBA, GO:0005634=IBA, GO:0008270=IEA, GO:0003677=IEA} regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter nucleus DNA binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, zinc ion binding Human PANTHER:PTN000003381 ZNF578 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96N58 Zinc finger protein 578 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF579 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8NAF0 Zinc finger protein 579 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF580 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9UK33 Zinc finger protein 580 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF581 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9P0T4 Zinc finger protein 581 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF584 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8IVC4 Zinc finger protein 584 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF585A UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q6P3V2 Zinc finger protein 585A protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF585B UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q52M93 Zinc finger protein 585B protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF586 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9NXT0 Zinc finger protein 586 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF587 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96SQ5 Zinc finger protein 587 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF592 UniProtKB UniProtKB {GO:0008219=GO_REF:0000037, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q92610 Zinc finger protein 592 protein 20130413 {GO:0008219=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} cell death, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF593 PINC UniProtKB {GO:0003714=PMID:9115366, GO:0005730=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0000122=PMID:9115366, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O00488 Zinc finger protein 593 protein 20030904 {GO:0003714=TAS, GO:0005730=IEA, GO:0008270=IEA, GO:0000122=TAS, GO:0003677=IEA, GO:0006351=IEA} negative regulation of transcription from RNA polymerase II promoter, transcription, DNA-dependent nucleolus DNA binding, transcription corepressor activity, zinc ion binding Human ZNF594 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96JF6 Zinc finger protein 594 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF595 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8IYB9 Zinc finger protein 595 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF596 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8TC21 Zinc finger protein 596 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF597 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96LX8 Zinc finger protein 597 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF598 InterPro UniProtKB {GO:0008270=GO_REF:0000002} Q86UK7 Zinc finger protein 598 protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR001841|InterPro:IPR007087 ZNF599 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96NL3 Zinc finger protein 599 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF600 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6ZNG1 Zinc finger protein 600 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF605 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q86T29 Zinc finger protein 605 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF606 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8WXB4 Zinc finger protein 606 protein 20111111 {GO:0005737=IDA, GO:0006355=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleolus, nucleus DNA binding, nucleic acid binding, zinc ion binding Human ZNF607 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96SK3 Zinc finger protein 607 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF608 InterPro UniProtKB {GO:0008270=GO_REF:0000002} Q9ULD9 Zinc finger protein 608 protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR007087 ZNF609 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002} O15014 Zinc finger protein 609 protein 20130413 {GO:0005634=IEA, GO:0008270=IEA} nucleus zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF610 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8N9Z0 Zinc finger protein 610 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF611 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8N823 Zinc finger protein 611 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF615 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8N8J6 Zinc finger protein 615 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF616 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q08AN1 Zinc finger protein 616 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF620 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6ZNG0 Zinc finger protein 620 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF622 HPA UniProtKB {GO:0005515=PMID:21771788, GO:0033674=PMID:21771788, GO:0005737=GO_REF:0000052, GO:0005794=GO_REF:0000052, GO:0043065=PMID:21771788, GO:0008631=PMID:21771788, GO:0005730=GO_REF:0000052, GO:0046330=PMID:21771788, GO:0008270=GO_REF:0000002, GO:0043410=PMID:21771788, GO:0003676=GO_REF:0000002} Q969S3 Zinc finger protein 622 protein 20110516 {GO:0005515=IPI, GO:0033674=IDA, GO:0005737=IDA, GO:0005794=IDA, GO:0043065=IDA, GO:0008631=IDA, GO:0005730=IDA, GO:0046330=IMP, GO:0008270=IEA, GO:0043410=IDA, GO:0003676=IEA} intrinsic apoptotic signaling pathway in response to oxidative stress, positive regulation of JNK cascade, positive regulation of MAPK cascade, positive regulation of apoptotic process, positive regulation of kinase activity Golgi apparatus, cytoplasm, nucleolus nucleic acid binding, protein binding, zinc ion binding Human ZNF623 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O75123 Zinc finger protein 623 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF624 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9P2J8 Zinc finger protein 624 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF625 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96I27 Zinc finger protein 625 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF626 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q68DY1 Zinc finger protein 626 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF627 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q7L945 Zinc finger protein 627 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF629 HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9UEG4 Zinc finger protein 629 protein 20090616 {GO:0006355=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human ZNF638 HPA UniProtKB {GO:0008380=PMID:8647861, GO:0006355=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0043231=GO_REF:0000052, GO:0005737=PMID:8647861, GO:0003690=PMID:8647861, GO:0000166=GO_REF:0000002, GO:0016607=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0005654=PMID:8647861} Q14966 Zinc finger protein 638 protein 20110516 {GO:0008380=TAS, GO:0006355=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0003676=IEA, GO:0006351=IEA, GO:0043231=IDA, GO:0005737=TAS, GO:0003690=TAS, GO:0000166=IEA, GO:0016607=IEA, GO:0008270=IEA, GO:0005654=TAS} RNA splicing, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, intracellular membrane-bounded organelle, nuclear speck, nucleolus, nucleoplasm, nucleus RNA binding, double-stranded DNA binding, nucleic acid binding, nucleotide binding, zinc ion binding Human ZNF639 UniProtKB UniProtKB {GO:0005515=PMID:16182284, GO:0003700=PMID:16182284, GO:0044212=PMID:20484494, GO:0030307=PMID:14522885, GO:0005634=PMID:14522885, GO:0008270=GO_REF:0000002, GO:0046718=PMID:20484494, GO:0043621=PMID:20484494, GO:0045892=PMID:16182284, GO:0043923=PMID:20484494, GO:0006351=GO_REF:0000037, GO:0043922=PMID:20484494} Q9UID6 Zinc finger protein 639 protein 20120816 {GO:0005515=IPI, GO:0003700=IDA, GO:0044212=IDA, GO:0030307=IMP, GO:0005634=IDA, GO:0008270=IEA, GO:0046718=IDA, GO:0043621=IPI, GO:0045892=IDA, GO:0043923=IMP, GO:0006351=IEA, GO:0043922=IMP} negative regulation by host of viral transcription, negative regulation of transcription, DNA-dependent, positive regulation by host of viral transcription, positive regulation of cell growth, transcription, DNA-dependent, viral entry into host cell nucleus protein binding, protein self-association, sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding, zinc ion binding Human ZNF641 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000002, GO:0006366=GO_REF:0000033, GO:0006357=GO_REF:0000033, GO:0000981=GO_REF:0000033, GO:0005730=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037} Q96N77 Zinc finger protein 641 protein 20101115 {GO:0005737=IDA, GO:0006355=IEA, GO:0006366=IBA, GO:0006357=IBA, GO:0000981=IBA, GO:0005730=IDA, GO:0008270=IEA, GO:0005634=IDA, GO:0003676=IEA, GO:0003677=IEA} regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter cytoplasm, nucleolus, nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, zinc ion binding Human ZNF644 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9H582 Zinc finger protein 644 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF645 UniPathway UniProtKB {GO:0005737=GO_REF:0000039, GO:0016567=GO_REF:0000041, GO:0016874=GO_REF:0000037, GO:0008270=GO_REF:0000002} Q8N7E2 E3 ubiquitin-protein ligase ZNF645 protein 20130413 {GO:0005737=IEA, GO:0016567=IEA, GO:0016874=IEA, GO:0008270=IEA} protein ubiquitination cytoplasm ligase activity, zinc ion binding Human UniPathway:UPA00143 ZNF646 IntAct UniProtKB {GO:0005515=PMID:19060904, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O15015 Zinc finger protein 646 protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, protein binding, zinc ion binding Human UniProtKB:Q99750 ZNF649 LIFEdb UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000054, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9BS31 Zinc finger protein 649 protein 20100607 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human ZNF652 IntAct UniProtKB {GO:0005515=PMID:16966434, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9Y2D9 Zinc finger protein 652 protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, protein binding, zinc ion binding Human UniProtKB:O75081 ZNF653 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96CK0 Zinc finger protein 653 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF655 IntAct UniProtKB {GO:0005515=PMID:15558030, GO:0005622=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0005737=PMID:15558030, GO:0006355=GO_REF:0000037, GO:0005730=PMID:15558030, GO:2000134=PMID:15558030, GO:0005634=PMID:15558030, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8N720 Zinc finger protein 655 protein 20130415 {GO:0005515=IPI, GO:0005622=IEA, GO:0003674=ND, GO:0005737=IDA, GO:0006355=IEA, GO:0005730=IDA, GO:2000134=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} negative regulation of G1/S transition of mitotic cell cycle, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, intracellular, nucleolus, nucleus DNA binding, molecular_function, nucleic acid binding, protein binding, zinc ion binding Human UniProtKB:P15498 ZNF660 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6AZW8 Zinc finger protein 660 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF664 LIFEdb UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000054, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8N3J9 Zinc finger protein 664 protein 20100607 {GO:0008150=ND, GO:0003674=ND, GO:0006355=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} biological_process, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, molecular_function, zinc ion binding Human ZNF665 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9H7R5 Zinc finger protein 665 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF667 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q5HYK9 Zinc finger protein 667 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF668 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96K58 Zinc finger protein 668 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF669 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96BR6 Zinc finger protein 669 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF670 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9BS34 Zinc finger protein 670 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF671 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8TAW3 Zinc finger protein 671 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF674 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q2M3X9 Zinc finger protein 674 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF675 BHF-UCL UniProtKB {GO:0048471=PMID:11751921, GO:0006355=GO_REF:0000002, GO:2000660=PMID:11751921, GO:0045453=PMID:11751921, GO:0019221=PMID:11751921, GO:0007249=PMID:11751921, GO:0032088=PMID:11751921, GO:0045671=PMID:11751921, GO:0005634=PMID:11751921, GO:0000122=PMID:11751921, GO:2000678=PMID:11751921, GO:0003676=GO_REF:0000002, GO:0010804=PMID:11751921, GO:0003677=PMID:11751921, GO:0006351=GO_REF:0000037, GO:0005622=GO_REF:0000002, GO:0046329=PMID:11751921, GO:0008270=PMID:11751921, GO:0043508=PMID:11751921, GO:0031625=PMID:11751921} Q8TD23 Zinc finger protein 675 protein 20110704 {GO:0048471=IDA, GO:0006355=IEA, GO:2000660=IDA, GO:0045453=TAS, GO:0019221=IDA, GO:0007249=IDA, GO:0032088=IDA, GO:0045671=IDA, GO:0005634=IDA, GO:0000122=IDA, GO:2000678=IDA, GO:0003676=IEA, GO:0010804=IDA, GO:0003677=NAS, GO:0006351=IEA, GO:0005622=IEA, GO:0046329=IDA, GO:0008270=NAS, GO:0043508=IDA, GO:0031625=IPI} I-kappaB kinase/NF-kappaB cascade, bone resorption, cytokine-mediated signaling pathway, negative regulation of JNK cascade, negative regulation of JUN kinase activity, negative regulation of NF-kappaB transcription factor activity, negative regulation of interleukin-1-mediated signaling pathway, negative regulation of osteoclast differentiation, negative regulation of transcription from RNA polymerase II promoter, negative regulation of transcription regulatory region DNA binding, negative regulation of tumor necrosis factor-mediated signaling pathway, regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus, perinuclear region of cytoplasm DNA binding, nucleic acid binding, ubiquitin protein ligase binding, zinc ion binding Human ZNF676 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8N7Q3 Zinc finger protein 676 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF677 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q86XU0 Zinc finger protein 677 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF678 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q5SXM1 Zinc finger protein 678 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF679 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8IYX0 Zinc finger protein 679 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF680 HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8NEM1 Zinc finger protein 680 protein 20080818 {GO:0006355=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus, nucleus DNA binding, zinc ion binding NOT Human ZNF681 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96N22 Zinc finger protein 681 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF682 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O95780 Zinc finger protein 682 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF684 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q5T5D9 Zinc finger protein 684 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human InterPro:IPR001909 ZNF687 HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8N1G0 Zinc finger protein 687 protein 20101115 {GO:0006355=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus, nucleus DNA binding, zinc ion binding Human ZNF688 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P0C7X2 Zinc finger protein 688 protein 20101021 {GO:0005622=IEA, GO:0003674=ND, GO:0008150=ND, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0005575=ND, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} biological_process, regulation of transcription, DNA-dependent, transcription, DNA-dependent cellular_component, intracellular, nucleus DNA binding, molecular_function, nucleic acid binding, zinc ion binding Human ZNF689 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96CS4 Zinc finger protein 689 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF691 UniProtKB UniProtKB {GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037} Q5VV52 Zinc finger protein 691 protein 20130413 {GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA} nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF695 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q8IW36 Zinc finger protein 695 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA} regulation of transcription, DNA-dependent intracellular, nucleus nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF696 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9H7X3 Zinc finger protein 696 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF699 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q32M78 Zinc finger protein 699 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF7 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0007275=PMID:2106481, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8N8Y4 cDNA FLJ38706 fis, clone KIDNE2002795, moderately similar to ZINC FINGER PROTEIN 7 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0007275=TAS, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} multicellular organismal development, regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human InterPro:IPR001909 ZNF70 UniProtKB UniProtKB {GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000029, GO:0005634=GO_REF:0000029, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9UC06 Zinc finger protein 70 protein 20021106 {GO:0006355=NAS, GO:0003700=NAS, GO:0005634=NAS, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZNF700 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9H0M5 Zinc finger protein 700 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF701 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9NV72 Zinc finger protein 701 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF703 UniProtKB UniProtKB {GO:0005515=PMID:21328542, GO:0008284=PMID:21328542, GO:0006355=PMID:21328542, GO:0030335=GO_REF:0000024, GO:0034333=GO_REF:0000024, GO:0010718=GO_REF:0000024, GO:0034111=GO_REF:0000024, GO:0005634=PMID:21337521, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0060828=GO_REF:0000024, GO:0005737=GO_REF:0000024, GO:0060644=PMID:21337521, GO:0070491=GO_REF:0000019, GO:0051726=PMID:21328542, GO:0008270=GO_REF:0000002, GO:0017015=PMID:21337521, GO:0045892=PMID:21337521, GO:0033601=PMID:21337521} Q9H7S9 Zinc finger protein 703 protein 20110222 {GO:0005515=IPI, GO:0008284=IDA, GO:0006355=IDA, GO:0030335=ISS, GO:0034333=ISS, GO:0010718=ISS, GO:0034111=ISS, GO:0005634=IDA, GO:0003676=IEA, GO:0006351=IEA, GO:0060828=ISS, GO:0005737=ISS, GO:0060644=IDA, GO:0070491=IEA, GO:0051726=IDA, GO:0008270=IEA, GO:0017015=IDA, GO:0045892=IMP, GO:0033601=IDA} adherens junction assembly, mammary gland epithelial cell differentiation, negative regulation of homotypic cell-cell adhesion, negative regulation of transcription, DNA-dependent, positive regulation of cell migration, positive regulation of cell proliferation, positive regulation of epithelial to mesenchymal transition, positive regulation of mammary gland epithelial cell proliferation, regulation of canonical Wnt receptor signaling pathway, regulation of cell cycle, regulation of transcription, DNA-dependent, regulation of transforming growth factor beta receptor signaling pathway, transcription, DNA-dependent cytoplasm, nucleus nucleic acid binding, protein binding, repressing transcription factor binding, zinc ion binding Human ZNF705G UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} A8MUZ8 Putative zinc finger protein 705G protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF706 UniProtKB UniProtKB {GO:0046872=GO_REF:0000037} Q9Y5V0 Zinc finger protein 706 protein 20130413 {GO:0046872=IEA} metal ion binding Human UniProtKB-KW:KW-0479 ZNF707 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96C28 Zinc finger protein 707 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF708 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P17019 Zinc finger protein 708 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF709 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8N972 Zinc finger protein 709 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF71 UniProtKB UniProtKB {GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000029, GO:0005634=GO_REF:0000029, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9NQZ8 Endothelial zinc finger protein induced by tumor necrosis factor alpha protein 20050308 {GO:0006355=NAS, GO:0003700=NAS, GO:0005634=NAS, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZNF711 UniProtKB UniProtKB {GO:0005515=PMID:20346720, GO:0043565=PMID:20346720, GO:0006355=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0005634=PMID:20346720, GO:0045893=PMID:20346720, GO:0003677=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q9Y462 Zinc finger protein 711 protein 20100819 {GO:0005515=IPI, GO:0043565=IDA, GO:0006355=IEA, GO:0008270=IEA, GO:0005634=IDA, GO:0045893=IMP, GO:0003677=IEA, GO:0006351=IEA} positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, protein binding, sequence-specific DNA binding, zinc ion binding Human UniProtKB:Q9UPP1 ZNF713 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8N859 Zinc finger protein 713 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF714 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96N38 Zinc finger protein 714 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF716 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} A6NP11 Zinc finger protein 716 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF717 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9BY31 Zinc finger protein 717 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF718 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q3SXZ3 Zinc finger protein 718 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF720 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q7Z2F6 Putative protein ZNF720 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0008270=IEA, GO:0003676=IEA} regulation of transcription, DNA-dependent intracellular nucleic acid binding, zinc ion binding Human InterPro:IPR001909 ZNF721 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8TF20 Zinc finger protein 721 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF726 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} M0R0X8 Zinc finger protein 726 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human InterPro:IPR007087 ZNF727 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} A8MUV8 Putative zinc finger protein 727 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF728 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} P0DKX0 Zinc finger protein 728 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0008270=IEA, GO:0003676=IEA} regulation of transcription, DNA-dependent intracellular nucleic acid binding, zinc ion binding Human InterPro:IPR007087 ZNF730 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6ZMV8 Putative zinc finger protein 730 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF732 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} B4DXR9 Zinc finger protein 732 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF735 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P0CB33 Putative zinc finger protein 735 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF736 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} B4DX44 Zinc finger protein 736 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF737 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O75373 Zinc finger protein 737 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF74 HPA UniProtKB {GO:0006355=GO_REF:0000037, GO:0003723=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0007275=PMID:1639391, GO:0008270=GO_REF:0000002, GO:0015629=GO_REF:0000052, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q16587 Zinc finger protein 74 protein 20101115 {GO:0006355=IEA, GO:0003723=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0007275=TAS, GO:0008270=IEA, GO:0015629=IDA, GO:0003677=IEA, GO:0006351=IEA} multicellular organismal development, regulation of transcription, DNA-dependent, transcription, DNA-dependent actin cytoskeleton, nucleolus, nucleus DNA binding, RNA binding, zinc ion binding Human ZNF740 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q8NDX6 Zinc finger protein 740 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF746 IntAct UniProtKB {GO:0005515=PMID:21376232, GO:0006355=GO_REF:0000002, GO:0044212=PMID:21376232, GO:0005634=GO_REF:0000039, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037, GO:0005622=GO_REF:0000002, GO:0005737=PMID:21376232, GO:0070997=PMID:21376232, GO:0008270=GO_REF:0000002, GO:0045892=PMID:21376232, GO:0010941=PMID:21376232, GO:0031625=PMID:21376232} Q6NUN9 Zinc finger protein 746 protein 20130415 {GO:0005515=IPI, GO:0006355=IEA, GO:0044212=IDA, GO:0005634=IEA, GO:0003676=IEA, GO:0006351=IEA, GO:0005622=IEA, GO:0005737=IDA, GO:0070997=IDA, GO:0008270=IEA, GO:0045892=IDA, GO:0010941=IDA, GO:0031625=IPI} negative regulation of transcription, DNA-dependent, neuron death, regulation of cell death, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, intracellular, nucleus nucleic acid binding, protein binding, transcription regulatory region DNA binding, ubiquitin protein ligase binding, zinc ion binding Human UniProtKB:O60260 ZNF747 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q9BV97 KRAB domain-containing protein ZNF747 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0008270=IEA, GO:0003676=IEA} regulation of transcription, DNA-dependent intracellular nucleic acid binding, zinc ion binding Human InterPro:IPR001909 ZNF749 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O43361 Zinc finger protein 749 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF75A UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96N20 Zinc finger protein 75A protein 20061106 {GO:0005622=IEA, GO:0003674=ND, GO:0008150=ND, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} biological_process, regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, molecular_function, nucleic acid binding, zinc ion binding Human ZNF75D UniProtKB UniProtKB {GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000002, GO:0016032=GO_REF:0000002, GO:0005634=GO_REF:0000029, GO:0008270=PMID:8288223, GO:0003677=GO_REF:0000029, GO:0006351=GO_REF:0000037} P51815 Zinc finger protein 75D protein 20021104 {GO:0006355=NAS, GO:0003700=IEA, GO:0016032=IEA, GO:0005634=NAS, GO:0008270=NAS, GO:0003677=NAS, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent, viral reproduction nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZNF76 InterPro UniProtKB {GO:0006357=PMID:9705341, GO:0006359=PMID:9705341, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q5R3B9 Zinc finger protein 76 protein 20130413 {GO:0006357=TAS, GO:0006359=TAS, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase III promoter, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human InterPro:IPR007087 ZNF761 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q86XN6 Zinc finger protein 761 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF763 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q0D2J5 Zinc finger protein 763 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF764 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96H86 Zinc finger protein 764 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF765 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q7L2R6 Zinc finger protein 765 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF766 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q5HY98 Zinc finger protein 766 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF768 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0006366=GO_REF:0000002, GO:0005665=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037} Q9H5H4 Zinc finger protein 768 protein 20130413 {GO:0006355=IEA, GO:0006366=IEA, GO:0005665=IEA, GO:0008270=IEA, GO:0003677=IEA} regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter DNA-directed RNA polymerase II, core complex DNA binding, zinc ion binding Human UniProtKB-KW:KW-0805 ZNF77 HPA UniProtKB {GO:0008150=GO_REF:0000015, GO:0003674=GO_REF:0000015, GO:0005737=GO_REF:0000052, GO:0006355=GO_REF:0000037, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q15935 Zinc finger protein 77 protein 20101115 {GO:0008150=ND, GO:0003674=ND, GO:0005737=IDA, GO:0006355=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} biological_process, regulation of transcription, DNA-dependent, transcription, DNA-dependent cytoplasm, nucleolus, nucleus DNA binding, molecular_function, zinc ion binding Human ZNF770 GOC UniProtKB {GO:0006366=GO_REF:0000033, GO:0006357=GO_REF:0000033, GO:0000981=GO_REF:0000033, GO:0005634=GO_REF:0000033, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037} Q6IQ21 Zinc finger protein 770 protein 20130413 {GO:0006366=IBA, GO:0006357=IBA, GO:0000981=IBA, GO:0005634=IBA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA} regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, zinc ion binding Human PANTHER:PTN000003381 ZNF772 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q68DY9 Zinc finger protein 772 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF773 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6PK81 Zinc finger protein 773 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF775 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96BV0 Zinc finger protein 775 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF777 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9ULD5 Zinc finger protein 777 protein 20090630 {GO:0003674=ND, GO:0008150=ND, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0005575=ND, GO:0003677=IEA, GO:0006351=IEA} biological_process, regulation of transcription, DNA-dependent, transcription, DNA-dependent cellular_component, nucleus DNA binding, molecular_function, zinc ion binding Human ZNF778 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96MU6 Zinc finger protein 778 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF781 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8N8C0 Zinc finger protein 781 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF782 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6ZMW2 Zinc finger protein 782 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF784 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8NCA9 Zinc finger protein 784 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF785 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} I3L119 Zinc finger protein 785 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human InterPro:IPR001909 ZNF787 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6DD87 Zinc finger protein 787 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF789 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q5FWF6 Zinc finger protein 789 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF79 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000029, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q15937 Zinc finger protein 79 protein 20021106 {GO:0005622=IEA, GO:0003674=ND, GO:0008150=ND, GO:0006355=IEA, GO:0005634=NAS, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} biological_process, regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, molecular_function, nucleic acid binding, zinc ion binding Human ZNF790 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6PG37 Zinc finger protein 790 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF791 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q3KP31 Zinc finger protein 791 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF792 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q3KQV3 Zinc finger protein 792 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF799 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96GE5 Zinc finger protein 799 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF8 UniProtKB UniProtKB {GO:0006355=GO_REF:0000029, GO:0008270=PMID:2106481, GO:0005634=GO_REF:0000029, GO:0030509=GO_REF:0000019, GO:0000122=GO_REF:0000019, GO:0003677=PMID:2106481, GO:0006351=GO_REF:0000037} P17098 Zinc finger protein 8 protein 20010905 {GO:0006355=NAS, GO:0008270=NAS, GO:0005634=NAS, GO:0030509=IEA, GO:0000122=IEA, GO:0003677=NAS, GO:0006351=IEA} BMP signaling pathway, negative regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human ZNF80 UniProtKB UniProtKB {GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000029, GO:0005634=GO_REF:0000029, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P51504 Zinc finger protein 80 protein 20021104 {GO:0006355=NAS, GO:0003700=NAS, GO:0005634=NAS, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZNF800 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q2TB10 Zinc finger protein 800 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF804A InterPro UniProtKB {GO:0008270=GO_REF:0000002} Q7Z570 Zinc finger protein 804A protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR007087 ZNF808 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8N4W9 Zinc finger protein 808 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF813 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6ZN06 Zinc finger protein 813 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF816 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q0VGE8 Zinc finger protein 816 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF821 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O75541 Zinc finger protein 821 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF823 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P16415 Zinc finger protein 823 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF827 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q17R98 Zinc finger protein 827 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF829 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q3KNS6 Zinc finger protein 829 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF83 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000029, GO:0003700=GO_REF:0000029, GO:0005634=GO_REF:0000029, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P51522 Zinc finger protein 83 protein 20021104 {GO:0005622=IEA, GO:0006355=NAS, GO:0003700=NAS, GO:0005634=NAS, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZNF830 HPA UniProtKB {GO:0005737=GO_REF:0000052, GO:0007067=GO_REF:0000037, GO:0007049=GO_REF:0000019, GO:0001832=GO_REF:0000019, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0046872=GO_REF:0000037, GO:0051301=GO_REF:0000037} Q96NB3 Zinc finger protein 830 protein 20100326 {GO:0005737=IDA, GO:0007067=IEA, GO:0007049=IEA, GO:0001832=IEA, GO:0005730=IDA, GO:0005634=IDA, GO:0046872=IEA, GO:0051301=IEA} blastocyst growth, cell cycle, cell division, mitosis cytoplasm, nucleolus, nucleus metal ion binding Human ZNF836 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6ZNA1 Zinc finger protein 836 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF839 InterPro UniProtKB {GO:0008270=GO_REF:0000002} H0YM94 Zinc finger protein 839 protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR007087 ZNF84 HPA UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000029, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=PMID:2505992, GO:0003676=GO_REF:0000002, GO:0003677=PMID:2505992, GO:0006351=GO_REF:0000037} P51523 Zinc finger protein 84 protein 20101115 {GO:0005622=IEA, GO:0006355=NAS, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=NAS, GO:0003676=IEA, GO:0003677=NAS, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleolus, nucleus DNA binding, nucleic acid binding, zinc ion binding NOT Human ZNF841 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q6ZN19 Zinc finger protein 841 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF844 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q08AG5 Zinc finger protein 844 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF845 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96IR2 Zinc finger protein 845 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF846 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q147U1 Zinc finger protein 846 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF85 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0003700=PMID:9839802, GO:0003714=PMID:9839802, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q96HE0 Zinc finger protein 85 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0003700=TAS, GO:0003714=TAS, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding transcription factor activity, transcription corepressor activity, zinc ion binding Human InterPro:IPR001909 ZNF850 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} K7EJI8 Zinc finger protein 850 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human InterPro:IPR001909 ZNF852 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q6ZMS4 Putative zinc finger protein 852 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0008270=IEA, GO:0003676=IEA} regulation of transcription, DNA-dependent intracellular nucleic acid binding, zinc ion binding Human InterPro:IPR007087 ZNF860 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} A6NHJ4 Zinc finger protein 860 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF862 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0006355=GO_REF:0000037, GO:0046983=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0005575=GO_REF:0000015, GO:0003676=GO_REF:0000002, GO:0046872=GO_REF:0000037, GO:0006351=GO_REF:0000037} O60290 Zinc finger protein 862 protein 20090701 {GO:0003674=ND, GO:0008150=ND, GO:0006355=IEA, GO:0046983=IEA, GO:0005634=IEA, GO:0005575=ND, GO:0003676=IEA, GO:0046872=IEA, GO:0006351=IEA} biological_process, regulation of transcription, DNA-dependent, transcription, DNA-dependent cellular_component, nucleus metal ion binding, molecular_function, nucleic acid binding, protein dimerization activity Human ZNF865 UniProtKB UniProtKB {GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P0CJ78 Zinc finger protein 865 protein 20130413 {GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus DNA binding, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZNF878 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} M0R1P6 Zinc finger protein 878 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus nucleic acid binding, zinc ion binding Human InterPro:IPR007087 ZNF879 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} E5RJY9 Zinc finger protein 879 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human InterPro:IPR001909 ZNF880 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002} Q6PDB4 Zinc finger protein 880 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0008270=IEA, GO:0003676=IEA} regulation of transcription, DNA-dependent intracellular nucleic acid binding, zinc ion binding Human InterPro:IPR007087 ZNF90 HPA UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000029, GO:0005794=GO_REF:0000052, GO:0003700=PMID:2023909, GO:0005634=GO_REF:0000052, GO:0008270=PMID:2023909, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q03938 Zinc finger protein 90 protein 20081203 {GO:0005622=IEA, GO:0006355=NAS, GO:0005794=IDA, GO:0003700=NAS, GO:0005634=IDA, GO:0008270=NAS, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent Golgi apparatus, intracellular, nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZNF91 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000029, GO:0003700=PMID:2023909, GO:0005634=GO_REF:0000029, GO:0008270=PMID:8467795, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q05481 Zinc finger protein 91 protein 20010905 {GO:0005622=IEA, GO:0006355=NAS, GO:0003700=NAS, GO:0005634=NAS, GO:0008270=NAS, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZNF92 HPA UniProtKB {GO:0006355=GO_REF:0000029, GO:0003700=PMID:2023909, GO:0005730=GO_REF:0000052, GO:0005634=GO_REF:0000052, GO:0008270=PMID:2023909, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q03936 Zinc finger protein 92 protein 20080818 {GO:0006355=NAS, GO:0003700=NAS, GO:0005730=IDA, GO:0005634=IDA, GO:0008270=NAS, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleolus, nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding transcription factor activity, zinc ion binding NOT Human ZNF93 UniProtKB UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000029, GO:0003700=PMID:2023909, GO:0005634=GO_REF:0000029, GO:0008270=PMID:2023909, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P35789 Zinc finger protein 93 protein 20021104 {GO:0005622=IEA, GO:0006355=NAS, GO:0003700=NAS, GO:0005634=NAS, GO:0008270=NAS, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZNF98 InterPro UniProtKB {GO:0005622=GO_REF:0000002, GO:0006355=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} M0R243 Zinc finger protein 98 protein 20130413 {GO:0005622=IEA, GO:0006355=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent intracellular, nucleus DNA binding, nucleic acid binding, zinc ion binding Human InterPro:IPR001909 ZNFX1 UniProtKB UniProtKB {GO:0046872=GO_REF:0000037} Q9P2E3 NFX1-type zinc finger-containing protein 1 protein 20130413 {GO:0046872=IEA} metal ion binding Human UniProtKB-KW:KW-0479 ZNHIT1 UniProtKB UniProtKB {GO:0005515=PMID:17577209, GO:0046872=GO_REF:0000037} O43257 Zinc finger HIT domain-containing protein 1 protein 20090724 {GO:0005515=IPI, GO:0046872=IEA} metal ion binding, protein binding Human UniProtKB:Q9BQA5 ZNHIT2 UniProtKB UniProtKB {GO:0046872=GO_REF:0000037} Q9UHR6 Zinc finger HIT domain-containing protein 2 protein 20130413 {GO:0046872=IEA} metal ion binding Human UniProtKB-KW:KW-0479 ZNHIT3 UniProtKB UniProtKB {GO:0005622=PMID:7776974, GO:0046966=PMID:7776974, GO:0006355=PMID:7776974, GO:0046872=GO_REF:0000037} Q15649 Zinc finger HIT domain-containing protein 3 protein 20010903 {GO:0005622=NAS, GO:0046966=TAS, GO:0006355=TAS, GO:0046872=IEA} regulation of transcription, DNA-dependent intracellular metal ion binding, thyroid hormone receptor binding Human ZNHIT6 BHF-UCL UniProtKB {GO:0005515=PMID:17636026, GO:0042254=GO_REF:0000037, GO:0070761=PMID:17636026, GO:0000492=PMID:17636026, GO:0046872=GO_REF:0000037, GO:0042802=PMID:17636026} Q9NWK9 Box C/D snoRNA protein 1 protein 20090629 {GO:0005515=IPI, GO:0042254=IEA, GO:0070761=IDA, GO:0000492=IMP, GO:0046872=IEA, GO:0042802=IPI} box C/D snoRNP assembly, ribosome biogenesis pre-snoRNP complex identical protein binding, metal ion binding, protein binding Human ZNRD1 PINC UniProtKB {GO:0006139=PMID:10662553, GO:0003899=GO_REF:0000037, GO:0005730=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000002} Q9P1U0 DNA-directed RNA polymerase I subunit RPA12 protein 20030904 {GO:0006139=TAS, GO:0003899=IEA, GO:0005730=IEA, GO:0008270=IEA, GO:0003676=IEA, GO:0006351=IEA} nucleobase-containing compound metabolic process, transcription, DNA-dependent nucleolus DNA-directed RNA polymerase activity, nucleic acid binding, zinc ion binding Human ZNRF1 IntAct UniProtKB {GO:0005515=PMID:19690564, GO:0004842=GO_REF:0000024, GO:0030054=GO_REF:0000037, GO:0030672=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0043161=GO_REF:0000024, GO:0070936=GO_REF:0000024, GO:0005764=GO_REF:0000039, GO:0005768=GO_REF:0000054} Q8ND25 E3 ubiquitin-protein ligase ZNRF1 protein 20130415 {GO:0005515=IPI, GO:0004842=ISS, GO:0030054=IEA, GO:0030672=IEA, GO:0008270=IEA, GO:0043161=ISS, GO:0070936=ISS, GO:0005764=IEA, GO:0005768=IDA} proteasomal ubiquitin-dependent protein catabolic process, protein K48-linked ubiquitination cell junction, endosome, lysosome, synaptic vesicle membrane protein binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q9Y2X8 ZNRF2 UniPathway UniProtKB {GO:0042734=GO_REF:0000039, GO:0016567=GO_REF:0000041, GO:0030054=GO_REF:0000037, GO:0005886=GO_REF:0000037, GO:0016874=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0005765=GO_REF:0000039, GO:0010008=GO_REF:0000039} Q8NHG8 E3 ubiquitin-protein ligase ZNRF2 protein 20130413 {GO:0042734=IEA, GO:0016567=IEA, GO:0030054=IEA, GO:0005886=IEA, GO:0016874=IEA, GO:0008270=IEA, GO:0005765=IEA, GO:0010008=IEA} protein ubiquitination cell junction, endosome membrane, lysosomal membrane, plasma membrane, presynaptic membrane ligase activity, zinc ion binding Human UniPathway:UPA00143 ZNRF3 UniProtKB UniProtKB {GO:0005515=PMID:22575959, GO:0006511=PMID:22575959, GO:0004842=PMID:22575959, GO:0016567=PMID:22575959, GO:0072089=GO_REF:0000024, GO:0005109=PMID:22575959, GO:0038018=PMID:22575959, GO:2000051=PMID:22575959, GO:0005887=PMID:22575959, GO:0008270=GO_REF:0000002, GO:0060070=GO_REF:0000019, GO:0090090=PMID:22575959, GO:0060071=GO_REF:0000019} Q9ULT6 E3 ubiquitin-protein ligase ZNRF3 protein 20120629 {GO:0005515=IPI, GO:0006511=IMP, GO:0004842=IDA, GO:0016567=IDA, GO:0072089=ISS, GO:0005109=IPI, GO:0038018=IMP, GO:2000051=IMP, GO:0005887=IDA, GO:0008270=IEA, GO:0060070=IEA, GO:0090090=IMP, GO:0060071=IEA} Wnt receptor catabolic process, Wnt receptor signaling pathway, planar cell polarity pathway, canonical Wnt receptor signaling pathway, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of non-canonical Wnt receptor signaling pathway, protein ubiquitination, stem cell proliferation, ubiquitin-dependent protein catabolic process integral to plasma membrane frizzled binding, protein binding, ubiquitin-protein ligase activity, zinc ion binding Human UniProtKB:Q9H461 ZNRF4 ENSEMBL UniProtKB {GO:0005737=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0016021=GO_REF:0000037} Q8WWF5 Zinc/RING finger protein 4 protein 20130413 {GO:0005737=IEA, GO:0008270=IEA, GO:0016021=IEA} cytoplasm, integral to membrane zinc ion binding Human Ensembl:ENSMUSP00000059715 ZP2 UniProtKB UniProtKB {GO:0060046=PMID:11751269, GO:0005794=GO_REF:0000024, GO:0005886=GO_REF:0000024, GO:0005783=GO_REF:0000024, GO:0005771=GO_REF:0000024, GO:0005578=GO_REF:0000039, GO:0005576=GO_REF:0000038, GO:0015026=PMID:8385033, GO:0032190=PMID:15950651, GO:0007339=PMID:22472438, GO:0006886=GO_REF:0000024, GO:0031012=GO_REF:0000024, GO:0060468=PMID:22472438, GO:0016021=GO_REF:0000037, GO:0006828=GO_REF:0000024, GO:0030141=GO_REF:0000024} Q4VAP1 ZP2 protein protein 20130413 {GO:0060046=IDA, GO:0005794=ISS, GO:0005886=ISS, GO:0005783=ISS, GO:0005771=ISS, GO:0005578=IEA, GO:0005576=IEA, GO:0015026=TAS, GO:0032190=IPI, GO:0007339=ISS, GO:0006886=ISS, GO:0031012=ISS, GO:0060468=ISS, GO:0016021=IEA, GO:0006828=ISS, GO:0030141=ISS} binding of sperm to zona pellucida, intracellular protein transport, manganese ion transport, prevention of polyspermy, regulation of acrosome reaction Golgi apparatus, endoplasmic reticulum, extracellular matrix, extracellular region, integral to membrane, multivesicular body, plasma membrane, proteinaceous extracellular matrix, secretory granule acrosin binding, coreceptor activity Human UniProtKB-KW:KW-0964 ZP3 GOC UniProtKB {GO:0005515=PMID:19945174, GO:0032753=GO_REF:0000024, GO:0006886=GO_REF:0000024, GO:0048599=GO_REF:0000024, GO:0005615=PMID:19246320, GO:0045860=PMID:18667750, GO:2000388=GO_REF:0000024, GO:0015279=PMID:20394732, GO:0035803=GO_REF:0000024, GO:2000386=GO_REF:0000024, GO:0032729=GO_REF:0000024, GO:0005794=GO_REF:0000024, GO:0010513=GO_REF:0000024, GO:0001809=GO_REF:0000024, GO:0045893=GO_REF:0000024, GO:0045892=GO_REF:0000024, GO:0071421=GO_REF:0000024, GO:0002455=GO_REF:0000024, GO:0051897=GO_REF:0000024, GO:0048471=GO_REF:0000024, GO:0005886=GO_REF:0000024, GO:0005783=GO_REF:0000024, GO:0032190=PMID:15950651, GO:0090280=PMID:11751269, GO:0035556=PMID:18667750, GO:0005737=PMID:9609824, GO:0042102=GO_REF:0000024, GO:0004871=PMID:18667750, GO:2000368=PMID:19246320, GO:0002081=GO_REF:0000024, GO:0030141=GO_REF:0000024, GO:0002922=PMID:19004505, GO:2000360=PMID:18667750, GO:0001669=GO_REF:0000024, GO:0048015=GO_REF:0000024, GO:0005771=GO_REF:0000024, GO:0001825=GO_REF:0000024, GO:0005578=GO_REF:0000039, GO:0005576=GO_REF:0000038, GO:0007339=PMID:19246320, GO:2000344=PMID:18667750, GO:0070528=PMID:18667750, GO:0031012=PMID:19246320, GO:0005384=GO_REF:0000024, GO:0002687=GO_REF:0000024, GO:0050729=GO_REF:0000024, GO:0030246=PMID:19246320, GO:0016021=GO_REF:0000037, GO:0006828=GO_REF:0000024} P21754 Zona pellucida sperm-binding protein 3 protein 20130413 {GO:0005515=IPI, GO:0032753=ISS, GO:0006886=ISS, GO:0048599=ISS, GO:0005615=IMP, GO:0045860=IDA, GO:2000388=ISS, GO:0015279=IDA, GO:0035803=ISS, GO:2000386=ISS, GO:0032729=ISS, GO:0005794=ISS, GO:0010513=ISS, GO:0001809=ISS, GO:0045893=ISS, GO:0045892=ISS, GO:0071421=ISS, GO:0002455=ISS, GO:0051897=ISS, GO:0048471=ISS, GO:0005886=ISS, GO:0005783=ISS, GO:0032190=IPI, GO:0090280=IDA, GO:0035556=IMP, GO:0005737=IDA, GO:0042102=ISS, GO:0004871=IMP, GO:2000368=IDA, GO:0002081=ISS, GO:0030141=ISS, GO:0002922=IDA, GO:2000360=IDA, GO:0001669=ISS, GO:0048015=ISS, GO:0005771=ISS, GO:0001825=ISS, GO:0005578=IEA, GO:0005576=IEA, GO:0007339=IDA, GO:2000344=IDA, GO:0070528=IMP, GO:0031012=IDA, GO:0005384=ISS, GO:0002687=ISS, GO:0050729=ISS, GO:0030246=IDA, GO:0016021=IEA, GO:0006828=ISS} binding of sperm to zona pellucida, blastocyst formation, egg coat formation, humoral immune response mediated by circulating immunoglobulin, intracellular protein transport, intracellular signal transduction, manganese ion transmembrane transport, manganese ion transport, negative regulation of binding of sperm to zona pellucida, negative regulation of transcription, DNA-dependent, oocyte development, phosphatidylinositol-mediated signaling, positive regulation of T cell proliferation, positive regulation of acrosomal vesicle exocytosis, positive regulation of acrosome reaction, positive regulation of antral ovarian follicle growth, positive regulation of calcium ion import, positive regulation of humoral immune response, positive regulation of inflammatory response, positive regulation of interferon-gamma production, positive regulation of interleukin-4 production, positive regulation of leukocyte migration, positive regulation of ovarian follicle development, positive regulation of phosphatidylinositol biosynthetic process, positive regulation of protein kinase B signaling cascade, positive regulation of protein kinase activity, positive regulation of transcription, DNA-dependent, positive regulation of type IV hypersensitivity, protein kinase C signaling cascade Golgi apparatus, acrosomal vesicle, cytoplasm, endoplasmic reticulum, extracellular matrix, extracellular region, extracellular space, integral to membrane, multivesicular body, outer acrosomal membrane, perinuclear region of cytoplasm, plasma membrane, proteinaceous extracellular matrix, secretory granule acrosin binding, carbohydrate binding, manganese ion transmembrane transporter activity, protein binding, signal transducer activity, store-operated calcium channel activity Human UniProtKB:P10761 ZP4 UniProtKB UniProtKB {GO:2000360=PMID:18667750, GO:0005886=GO_REF:0000039, GO:0005578=GO_REF:0000039, GO:0010737=PMID:18667750, GO:0032190=PMID:15950651, GO:2000344=PMID:18667750, GO:0070528=PMID:18667750, GO:0035556=PMID:18667750, GO:0060478=PMID:19004505, GO:0042102=PMID:19004505, GO:0045860=PMID:18667750, GO:0016021=GO_REF:0000037, GO:0004871=PMID:18667750, GO:0002922=PMID:19004505} Q12836 Zona pellucida sperm-binding protein 4 protein 20110228 {GO:2000360=IDA, GO:0005886=IEA, GO:0005578=IEA, GO:0010737=IDA, GO:0032190=IPI, GO:2000344=IDA, GO:0070528=IMP, GO:0035556=IMP, GO:0060478=IMP, GO:0042102=IDA, GO:0045860=IDA, GO:0016021=IEA, GO:0004871=IMP, GO:0002922=IDA} acrosomal vesicle exocytosis, intracellular signal transduction, negative regulation of binding of sperm to zona pellucida, positive regulation of T cell proliferation, positive regulation of acrosome reaction, positive regulation of humoral immune response, positive regulation of protein kinase activity, protein kinase A signaling cascade, protein kinase C signaling cascade integral to membrane, plasma membrane, proteinaceous extracellular matrix acrosin binding, signal transducer activity Human ZPBP UniProtKB UniProtKB {GO:0001675=GO_REF:0000019, GO:0001669=GO_REF:0000019, GO:0005576=GO_REF:0000039, GO:0007339=GO_REF:0000002} Q9BS86 Zona pellucida-binding protein 1 protein 20130413 {GO:0001675=IEA, GO:0001669=IEA, GO:0005576=IEA, GO:0007339=IEA} acrosome assembly, binding of sperm to zona pellucida acrosomal vesicle, extracellular region Human UniProtKB-SubCell:SL-0243 ZRANB1 BHF-UCL UniProtKB {GO:0005515=PMID:11463333, GO:0004843=PMID:18281465, GO:0030177=PMID:18281465, GO:0005634=PMID:11463333, GO:0005737=PMID:11463333, GO:0071947=PMID:18281465, GO:0070536=PMID:18281465, GO:0016477=PMID:21834987, GO:0007010=PMID:21834987, GO:0022604=PMID:21834987, GO:0008270=GO_REF:0000002, GO:0004221=PMID:18281465, GO:0016055=GO_REF:0000037, GO:0070530=PMID:18281465} Q9UGI0 Ubiquitin thioesterase ZRANB1 protein 20110704 {GO:0005515=IPI, GO:0004843=IDA, GO:0030177=IMP, GO:0005634=IDA, GO:0005737=IDA, GO:0071947=IMP, GO:0070536=IMP, GO:0016477=IMP, GO:0007010=IMP, GO:0022604=IMP, GO:0008270=IEA, GO:0004221=IMP, GO:0016055=IEA, GO:0070530=IDA} Wnt receptor signaling pathway, cell migration, cytoskeleton organization, positive regulation of Wnt receptor signaling pathway, protein K63-linked deubiquitination, protein deubiquitination involved in ubiquitin-dependent protein catabolic process, regulation of cell morphogenesis cytoplasm, nucleus K63-linked polyubiquitin binding, protein binding, ubiquitin thiolesterase activity, ubiquitin-specific protease activity, zinc ion binding Human ZRANB2 GOC UniProtKB {GO:0005515=PMID:17620599, GO:0008380=GO_REF:0000037, GO:0006397=GO_REF:0000037, GO:0006355=PMID:9931435, GO:0003700=PMID:9931435, GO:0003723=GO_REF:0000037, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002} O95218 Zinc finger Ran-binding domain-containing protein 2 protein 20130413 {GO:0005515=IPI, GO:0008380=IEA, GO:0006397=IEA, GO:0006355=TAS, GO:0003700=TAS, GO:0003723=IEA, GO:0005634=IEA, GO:0008270=IEA} RNA splicing, mRNA processing, regulation of transcription, DNA-dependent nucleus RNA binding, protein binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZRANB3 GOC UniProtKB {GO:0005515=PMID:22705370, GO:0036292=PMID:22705370, GO:0048478=PMID:22705370, GO:0004386=GO_REF:0000002, GO:0004520=PMID:22759634, GO:0003677=GO_REF:0000002, GO:0005524=GO_REF:0000037, GO:0003678=PMID:21078962, GO:0006974=PMID:22705370, GO:0005622=GO_REF:0000002, GO:0000733=PMID:22705370, GO:0036310=PMID:22705370, GO:0006281=PMID:22759634, GO:0004519=GO_REF:0000002, GO:0031297=PMID:22705370, GO:0008270=GO_REF:0000002, GO:0009411=PMID:22704558, GO:0043596=PMID:22705370, GO:0045910=PMID:22704558, GO:0070530=PMID:22705370} Q5FWF4 DNA annealing helicase and endonuclease ZRANB3 protein 20130413 {GO:0005515=IPI, GO:0036292=IDA, GO:0048478=IDA, GO:0004386=IEA, GO:0004520=IDA, GO:0003677=IEA, GO:0005524=IEA, GO:0003678=IDA, GO:0006974=IDA, GO:0005622=IEA, GO:0000733=IDA, GO:0036310=IDA, GO:0006281=IDA, GO:0004519=IEA, GO:0031297=IDA, GO:0008270=IEA, GO:0009411=IDA, GO:0043596=IDA, GO:0045910=IDA, GO:0070530=IDA} DNA repair, DNA rewinding, DNA strand renaturation, negative regulation of DNA recombination, replication fork processing, replication fork protection, response to DNA damage stimulus, response to UV intracellular, nuclear replication fork ATP binding, DNA binding, DNA helicase activity, K63-linked polyubiquitin binding, annealing helicase activity, endodeoxyribonuclease activity, endonuclease activity, helicase activity, protein binding, zinc ion binding Human ZRSR2 HGNC UniProtKB {GO:0008380=PMID:15146077, GO:0005515=PMID:9237760, GO:0000245=PMID:21041408, GO:0030628=PMID:21041408, GO:0000166=GO_REF:0000002, GO:0000398=PMID:9237760, GO:0008270=GO_REF:0000002, GO:0005689=PMID:15146077} Q15696 U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 protein 20060131 {GO:0008380=IC, GO:0005515=IPI, GO:0000245=IMP, GO:0030628=IDA, GO:0000166=IEA, GO:0000398=IMP, GO:0008270=IEA, GO:0005689=IDA} RNA splicing, mRNA splicing, via spliceosome, spliceosomal complex assembly U12-type spliceosomal complex nucleotide binding, pre-mRNA 3'-splice site binding, protein binding, zinc ion binding Human GO:0005689 ZSCAN1 GOC UniProtKB {GO:0006366=GO_REF:0000033, GO:0006357=GO_REF:0000033, GO:0000981=GO_REF:0000033, GO:0003713=GO_REF:0000033, GO:0016032=GO_REF:0000002, GO:0005634=GO_REF:0000033, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037} Q8NBB4 Zinc finger and SCAN domain-containing protein 1 protein 20130413 {GO:0006366=IBA, GO:0006357=IBA, GO:0000981=IBA, GO:0003713=IBA, GO:0016032=IEA, GO:0005634=IBA, GO:0008270=IEA, GO:0003677=IEA} regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter, viral reproduction nucleus DNA binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, transcription coactivator activity, zinc ion binding Human PANTHER:PTN000003381 ZSCAN12 UniProtKB UniProtKB {GO:0003700=GO_REF:0000002, GO:0016032=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} O43309 Zinc finger and SCAN domain-containing protein 12 protein 20130413 {GO:0003700=IEA, GO:0016032=IEA, GO:0005634=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} transcription, DNA-dependent, viral reproduction nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZSCAN16 HPA UniProtKB {GO:0003700=GO_REF:0000002, GO:0016032=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q9H4T2 Zinc finger and SCAN domain-containing protein 16 protein 20080205 {GO:0003700=IEA, GO:0016032=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} transcription, DNA-dependent, viral reproduction nucleus DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZSCAN18 GOC UniProtKB {GO:0003700=GO_REF:0000002, GO:0006366=GO_REF:0000033, GO:0006357=GO_REF:0000033, GO:0000981=GO_REF:0000033, GO:0016032=GO_REF:0000002, GO:0005634=GO_REF:0000033, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037} Q8TBC5 Zinc finger and SCAN domain-containing protein 18 protein 20130413 {GO:0003700=IEA, GO:0006366=IBA, GO:0006357=IBA, GO:0000981=IBA, GO:0016032=IEA, GO:0005634=IBA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA} regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter, viral reproduction nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity, zinc ion binding Human PANTHER:PTN000003381 ZSCAN2 UniProtKB UniProtKB {GO:0003700=GO_REF:0000002, GO:0016032=GO_REF:0000002, GO:0007275=GO_REF:0000037, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000039, GO:0007283=GO_REF:0000037, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0030154=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q7Z7L9 Zinc finger and SCAN domain-containing protein 2 protein 20130413 {GO:0003700=IEA, GO:0016032=IEA, GO:0007275=IEA, GO:0008270=IEA, GO:0005634=IEA, GO:0007283=IEA, GO:0003676=IEA, GO:0003677=IEA, GO:0030154=IEA, GO:0006351=IEA} cell differentiation, multicellular organismal development, spermatogenesis, transcription, DNA-dependent, viral reproduction nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB-SubCell:SL-0191 ZSCAN20 HPA UniProtKB {GO:0005739=GO_REF:0000052, GO:0003700=GO_REF:0000002, GO:0003682=GO_REF:0000002, GO:0005730=GO_REF:0000052, GO:0016032=GO_REF:0000002, GO:0005634=GO_REF:0000052, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P17040 Zinc finger and SCAN domain-containing protein 20 protein 20090616 {GO:0005739=IDA, GO:0003700=IEA, GO:0003682=IEA, GO:0005730=IDA, GO:0016032=IEA, GO:0005634=IDA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} transcription, DNA-dependent, viral reproduction mitochondrion, nucleolus, nucleus DNA binding, chromatin binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZSCAN21 UniProtKB UniProtKB {GO:0005515=PMID:19549071, GO:0006355=PMID:19549071, GO:0003700=GO_REF:0000002, GO:0016032=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000029, GO:0045893=GO_REF:0000029, GO:0003677=GO_REF:0000019, GO:0006351=GO_REF:0000037} Q9Y5A6 Zinc finger and SCAN domain-containing protein 21 protein 20090630 {GO:0005515=IPI, GO:0006355=IMP, GO:0003700=IEA, GO:0016032=IEA, GO:0008270=IEA, GO:0005634=NAS, GO:0045893=NAS, GO:0003677=IEA, GO:0006351=IEA} positive regulation of transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription, DNA-dependent, viral reproduction nucleus DNA binding, protein binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZSCAN22 UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0003700=GO_REF:0000002, GO:0016032=GO_REF:0000002, GO:0005634=GO_REF:0000029, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} P10073 Zinc finger and SCAN domain-containing protein 22 protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0003700=IEA, GO:0016032=IEA, GO:0005634=NAS, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} biological_process, transcription, DNA-dependent, viral reproduction nucleus DNA binding, molecular_function, sequence-specific DNA binding transcription factor activity, zinc ion binding Human ZSCAN29 GOC UniProtKB {GO:0003700=GO_REF:0000002, GO:0006366=GO_REF:0000033, GO:0006357=GO_REF:0000033, GO:0000981=GO_REF:0000033, GO:0016032=GO_REF:0000002, GO:0008270=GO_REF:0000002, GO:0005634=GO_REF:0000033, GO:0003677=GO_REF:0000037} Q8IWY8 Zinc finger and SCAN domain-containing protein 29 protein 20130413 {GO:0003700=IEA, GO:0006366=IBA, GO:0006357=IBA, GO:0000981=IBA, GO:0016032=IEA, GO:0008270=IEA, GO:0005634=IBA, GO:0003677=IEA} regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter, viral reproduction nucleus DNA binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity, zinc ion binding Human PANTHER:PTN000003381 ZSCAN4 UniProtKB UniProtKB {GO:0003700=GO_REF:0000002, GO:0016032=GO_REF:0000002, GO:0010833=GO_REF:0000024, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0000784=GO_REF:0000024, GO:0006351=GO_REF:0000037} Q8NAM6 Zinc finger and SCAN domain-containing protein 4 protein 20100329 {GO:0003700=IEA, GO:0016032=IEA, GO:0010833=ISS, GO:0008270=IEA, GO:0003677=IEA, GO:0000784=ISS, GO:0006351=IEA} telomere maintenance via telomere lengthening, transcription, DNA-dependent, viral reproduction nuclear chromosome, telomeric region DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB:Q80VJ6 ZSCAN5A GOC UniProtKB {GO:0003700=GO_REF:0000002, GO:0006366=GO_REF:0000033, GO:0006357=GO_REF:0000033, GO:0000981=GO_REF:0000033, GO:0016032=GO_REF:0000002, GO:0005634=GO_REF:0000033, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0003677=GO_REF:0000037} Q9BUG6 Zinc finger and SCAN domain-containing protein 5A protein 20130413 {GO:0003700=IEA, GO:0006366=IBA, GO:0006357=IBA, GO:0000981=IBA, GO:0016032=IEA, GO:0005634=IBA, GO:0008270=IEA, GO:0003676=IEA, GO:0003677=IEA} regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter, viral reproduction nucleus DNA binding, nucleic acid binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity, zinc ion binding Human PANTHER:PTN000003381 ZSWIM1 ENSEMBL UniProtKB {GO:0005634=GO_REF:0000019, GO:0008270=GO_REF:0000002} Q9BR11 Zinc finger SWIM domain-containing protein 1 protein 20130413 {GO:0005634=IEA, GO:0008270=IEA} nucleus zinc ion binding Human Ensembl:ENSMUSP00000017908 ZSWIM2 ENSEMBL UniProtKB {GO:0000209=GO_REF:0000019, GO:0004842=GO_REF:0000019, GO:0006915=GO_REF:0000037, GO:0042981=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0043621=GO_REF:0000019} Q8NEG5 E3 ubiquitin-protein ligase ZSWIM2 protein 20130413 {GO:0000209=IEA, GO:0004842=IEA, GO:0006915=IEA, GO:0042981=IEA, GO:0008270=IEA, GO:0043621=IEA} apoptotic process, protein polyubiquitination, regulation of apoptotic process protein self-association, ubiquitin-protein ligase activity, zinc ion binding Human Ensembl:ENSMUSP00000044913 ZSWIM3 InterPro UniProtKB {GO:0008270=GO_REF:0000002} Q96MP5 Zinc finger SWIM domain-containing protein 3 protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR006564|InterPro:IPR007527 ZSWIM4 InterPro UniProtKB {GO:0008270=GO_REF:0000002} Q9H7M6 Zinc finger SWIM domain-containing protein 4 protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR007527 ZSWIM6 ENSEMBL UniProtKB {GO:0048812=GO_REF:0000019, GO:2001222=GO_REF:0000019, GO:0008270=GO_REF:0000002} Q9HCJ5 Zinc finger SWIM domain-containing protein 6 protein 20130413 {GO:0048812=IEA, GO:2001222=IEA, GO:0008270=IEA} neuron projection morphogenesis, regulation of neuron migration zinc ion binding Human Ensembl:ENSMUSP00000100724 ZSWIM7 IntAct UniProtKB {GO:0005515=PMID:21965664, GO:0000724=PMID:21965664, GO:0050821=PMID:21965664, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0097196=PMID:21965664} Q19AV6 Zinc finger SWIM domain-containing protein 7 protein 20130415 {GO:0005515=IPI, GO:0000724=IMP, GO:0050821=IMP, GO:0005634=IEA, GO:0008270=IEA, GO:0097196=IDA} double-strand break repair via homologous recombination, protein stabilization Shu complex, nucleus protein binding, zinc ion binding Human UniProtKB:Q6NVH7 ZUFSP InterPro UniProtKB {GO:0008270=GO_REF:0000002} Q96AP4 Zinc finger with UFM1-specific peptidase domain protein protein 20130413 {GO:0008270=IEA} zinc ion binding Human InterPro:IPR007087 ZW10 BHF-UCL UniProtKB {GO:0005515=PMID:16732327, GO:0005828=PMID:11146660, GO:0000236=Reactome:REACT_682, GO:0007093=PMID:11146660, GO:0005783=PMID:15029241, GO:0034501=PMID:19468067, GO:0007096=PMID:11146660, GO:0000132=PMID:19468067, GO:0005634=PMID:15485811, GO:0015031=GO_REF:0000037, GO:0005829=Reactome:REACT_150414, GO:0000087=Reactome:REACT_910, GO:0019237=PMID:9700164, GO:0006888=PMID:15029241, GO:0000922=PMID:11146660, GO:0007067=GO_REF:0000002, GO:0000070=PMID:11146660, GO:0007126=PMID:9298984, GO:0006461=PMID:11146660, GO:0005789=GO_REF:0000039, GO:0000777=GO_REF:0000039, GO:0000776=PMID:11682612, GO:0007080=PMID:19468067, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0000775=GO_REF:0000002, GO:0051301=GO_REF:0000037} O43264 Centromere/kinetochore protein zw10 homolog protein 20091216 {GO:0005515=IPI, GO:0005828=IDA, GO:0000236=TAS, GO:0007093=IDA, GO:0005783=IDA, GO:0034501=IMP, GO:0007096=IDA, GO:0000132=IMP, GO:0005634=IDA, GO:0015031=IEA, GO:0005829=TAS, GO:0000087=TAS, GO:0019237=TAS, GO:0006888=IMP, GO:0000922=IDA, GO:0007067=IEA, GO:0000070=IDA, GO:0007126=TAS, GO:0006461=IDA, GO:0005789=IEA, GO:0000777=IEA, GO:0000776=IDA, GO:0007080=IMP, GO:0000278=TAS, GO:0000090=TAS, GO:0000775=IEA, GO:0051301=IEA} ER to Golgi vesicle-mediated transport, M phase of mitotic cell cycle, cell division, establishment of mitotic spindle orientation, meiosis, mitosis, mitotic anaphase, mitotic cell cycle, mitotic cell cycle checkpoint, mitotic metaphase plate congression, mitotic prometaphase, mitotic sister chromatid segregation, protein complex assembly, protein localization to kinetochore, protein transport, regulation of exit from mitosis chromosome, centromeric region, condensed chromosome kinetochore, cytosol, endoplasmic reticulum, endoplasmic reticulum membrane, kinetochore, kinetochore microtubule, nucleus, spindle pole centromeric DNA binding, protein binding Human ZWILCH Reactome UniProtKB {GO:0005515=PMID:12686595, GO:0000236=Reactome:REACT_682, GO:0007093=PMID:15824131, GO:0000087=Reactome:REACT_910, GO:0000777=GO_REF:0000039, GO:0000776=PMID:12686595, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0005829=Reactome:REACT_150414, GO:0051301=GO_REF:0000037} Q9H900 Protein zwilch homolog protein 20130213 {GO:0005515=IPI, GO:0000236=TAS, GO:0007093=IMP, GO:0000087=TAS, GO:0000777=IEA, GO:0000776=IDA, GO:0000278=TAS, GO:0000090=TAS, GO:0005829=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, cell division, mitotic anaphase, mitotic cell cycle, mitotic cell cycle checkpoint, mitotic prometaphase condensed chromosome kinetochore, cytosol, kinetochore protein binding Human ZWINT BHF-UCL UniProtKB {GO:0005515=PMID:20360068, GO:0000236=Reactome:REACT_682, GO:0007093=PMID:15485811, GO:0048015=PMID:15504738, GO:0005634=GO_REF:0000039, GO:0030425=GO_REF:0000019, GO:0005829=Reactome:REACT_150414, GO:0000070=PMID:15485811, GO:0005737=PMID:11682612, GO:0007049=PMID:15504738, GO:0047485=PMID:15485811, GO:0000087=Reactome:REACT_910, GO:0000777=GO_REF:0000039, GO:0000776=PMID:11682612, GO:0051649=PMID:15485811, GO:0007051=PMID:15504738, GO:0000278=Reactome:REACT_152, GO:0000090=Reactome:REACT_1275, GO:0051301=GO_REF:0000037} O95229 ZW10 interactor protein 20091216 {GO:0005515=IPI, GO:0000236=TAS, GO:0007093=IDA, GO:0048015=NAS, GO:0005634=IEA, GO:0030425=IEA, GO:0005829=TAS, GO:0000070=IDA, GO:0005737=IDA, GO:0007049=NAS, GO:0047485=IPI, GO:0000087=TAS, GO:0000777=IEA, GO:0000776=IDA, GO:0051649=IDA, GO:0007051=NAS, GO:0000278=TAS, GO:0000090=TAS, GO:0051301=IEA} M phase of mitotic cell cycle, cell cycle, cell division, establishment of localization in cell, mitotic anaphase, mitotic cell cycle, mitotic cell cycle checkpoint, mitotic prometaphase, mitotic sister chromatid segregation, phosphatidylinositol-mediated signaling, spindle organization condensed chromosome kinetochore, cytoplasm, cytosol, dendrite, kinetochore, nucleus protein N-terminus binding, protein binding Human ZXDA IntAct UniProtKB {GO:0005515=PMID:17493635, GO:0003700=PMID:17493635, GO:0070742=PMID:17493635, GO:0005634=GO_REF:0000029, GO:0008270=GO_REF:0000002, GO:0045893=PMID:17493635, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} P98168 Zinc finger X-linked protein ZXDA protein 20130415 {GO:0005515=IPI, GO:0003700=IMP, GO:0070742=IPI, GO:0005634=NAS, GO:0008270=IEA, GO:0045893=IMP, GO:0003676=IEA, GO:0006351=IEA} positive regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus C2H2 zinc finger domain binding, nucleic acid binding, protein binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB:Q2QGD7 ZXDB UniProtKB UniProtKB {GO:0003674=GO_REF:0000015, GO:0008150=GO_REF:0000015, GO:0006355=GO_REF:0000037, GO:0005634=GO_REF:0000029, GO:0008270=GO_REF:0000002, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} P98169 Zinc finger X-linked protein ZXDB protein 20061026 {GO:0003674=ND, GO:0008150=ND, GO:0006355=IEA, GO:0005634=NAS, GO:0008270=IEA, GO:0003676=IEA, GO:0006351=IEA} biological_process, regulation of transcription, DNA-dependent, transcription, DNA-dependent nucleus molecular_function, nucleic acid binding, zinc ion binding Human ZXDC IntAct UniProtKB {GO:0005515=PMID:17493635, GO:0003700=PMID:17493635, GO:0030275=PMID:16600381, GO:0070742=PMID:17493635, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0005575=GO_REF:0000015, GO:0045893=PMID:16600381, GO:0003676=GO_REF:0000002, GO:0006351=GO_REF:0000037} Q2QGD7 Zinc finger protein ZXDC protein 20130415 {GO:0005515=IPI, GO:0003700=IMP, GO:0030275=IPI, GO:0070742=IPI, GO:0005634=IEA, GO:0008270=IEA, GO:0005575=ND, GO:0045893=IMP, GO:0003676=IEA, GO:0006351=IEA} positive regulation of transcription, DNA-dependent, transcription, DNA-dependent cellular_component, nucleus C2H2 zinc finger domain binding, LRR domain binding, nucleic acid binding, protein binding, sequence-specific DNA binding transcription factor activity, zinc ion binding Human UniProtKB:P98168 ZYG11A null null {} null null null null {} null null null ZYG11B null null {} null null null null {} null null null ZYX HPA UniProtKB {GO:0007165=PMID:8940160, GO:0001725=PMID:18297730, GO:0005737=GO_REF:0000052, GO:0005913=PMID:8940160, GO:0005886=PMID:8940160, GO:0005887=PMID:8940160, GO:0019048=GO_REF:0000037, GO:0007267=PMID:8940160, GO:0005634=GO_REF:0000039, GO:0008270=GO_REF:0000002, GO:0007155=GO_REF:0000037, GO:0005925=GO_REF:0000052} Q15942 Zyxin protein 20101115 {GO:0007165=TAS, GO:0001725=IDA, GO:0005737=IDA, GO:0005913=IDA, GO:0005886=TAS, GO:0005887=TAS, GO:0019048=IEA, GO:0007267=TAS, GO:0005634=IEA, GO:0008270=IEA, GO:0007155=IEA, GO:0005925=IDA} cell adhesion, cell-cell signaling, signal transduction, virus-host interaction cell-cell adherens junction, cytoplasm, focal adhesion, integral to plasma membrane, nucleus, plasma membrane, stress fiber zinc ion binding Human ZZEF1 InterPro UniProtKB {GO:0005509=GO_REF:0000002, GO:0008270=GO_REF:0000002} O43149 Zinc finger ZZ-type and EF-hand domain-containing protein 1 protein 20130413 {GO:0005509=IEA, GO:0008270=IEA} calcium ion binding, zinc ion binding Human InterPro:IPR000433 ZZZ3 ENSEMBL UniProtKB {GO:0006355=GO_REF:0000037, GO:0003682=GO_REF:0000002, GO:0005671=GO_REF:0000019, GO:0008270=GO_REF:0000002, GO:0003677=GO_REF:0000037, GO:0006351=GO_REF:0000037} Q8IYH5 ZZ-type zinc finger-containing protein 3 protein 20130413 {GO:0006355=IEA, GO:0003682=IEA, GO:0005671=IEA, GO:0008270=IEA, GO:0003677=IEA, GO:0006351=IEA} regulation of transcription, DNA-dependent, transcription, DNA-dependent Ada2/Gcn5/Ada3 transcription activator complex DNA binding, chromatin binding, zinc ion binding Human Ensembl:ENSMUSP00000101706